# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Retrotrans_gag PF03732.17 GBG41013.1 - 7.5e-05 22.9 0.1 7.5e-05 22.9 0.1 3.5 2 2 1 3 3 3 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG41013.1 - 0.00096 19.7 2.3 0.00096 19.7 2.3 3.2 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 GBG41013.1 - 0.0057 17.1 1.0 0.067 13.7 0.1 2.5 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GBG41013.1 - 0.0065 15.9 14.1 0.066 12.5 8.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) SPARC_Ca_bdg PF10591.9 GBG41013.1 - 1.5 9.2 4.5 0.74 10.2 1.4 2.2 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ADIP PF11559.8 GBG41013.1 - 4.5 7.3 17.8 0.15 12.1 1.7 3.5 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding GHMP_kinases_C PF08544.13 GBG41014.1 - 0.029 14.7 0.2 4.2 7.8 0.1 2.9 2 2 0 2 2 2 0 GHMP kinases C terminal Casc1_N PF15927.5 GBG41014.1 - 0.1 12.3 15.3 0.21 11.2 15.3 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF3138 PF11336.8 GBG41063.1 - 0.72 8.4 5.0 0.32 9.6 3.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) NOA36 PF06524.12 GBG41066.1 - 0.02 14.3 15.6 0.022 14.1 13.7 1.8 2 0 0 2 2 2 0 NOA36 protein PPP4R2 PF09184.11 GBG41066.1 - 0.2 11.2 13.5 0.28 10.7 13.5 1.1 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 GBG41066.1 - 0.29 10.5 13.9 0.36 10.2 13.9 1.1 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 GBG41066.1 - 0.45 10.2 6.6 0.79 9.4 6.6 1.4 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 GBG41066.1 - 1.1 7.4 14.7 1.4 7.1 14.7 1.1 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.12 GBG41066.1 - 3.4 6.5 12.0 4.4 6.1 12.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Prefoldin PF02996.17 GBG41083.1 - 1.3e-18 67.1 0.3 2.9e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 GBG41083.1 - 1.4e-06 28.2 0.1 1.4e-06 28.2 0.1 2.7 3 1 0 3 3 3 1 Prefoldin subunit TFIIF_alpha PF05793.12 GBG41083.1 - 1.9 7.0 58.5 2.9 6.4 58.5 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Retrotrans_gag PF03732.17 GBG41088.1 - 0.0019 18.5 0.1 0.0019 18.5 0.1 3.5 4 0 0 4 4 4 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG41088.1 - 0.013 15.3 1.5 0.049 13.4 1.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG41088.1 - 0.018 14.4 7.3 0.038 13.3 7.3 1.5 1 0 0 1 1 1 0 FAM76 protein eIF3_subunit PF08597.10 GBG41088.1 - 0.63 9.9 12.6 1.1 9.1 12.6 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Cep57_MT_bd PF06657.13 GBG41088.1 - 3.6 8.1 0.0 3.6 8.1 0.0 3.8 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 zf-CCHC PF00098.23 GBG41102.1 - 0.0018 18.2 2.0 0.0018 18.2 2.0 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG41102.1 - 0.018 14.8 1.0 0.038 13.7 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2681 PF10883.8 GBG41102.1 - 7 7.1 13.3 3.9 7.9 3.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF3987 PF13148.6 GBG41102.1 - 9.4 5.1 14.8 0.24 10.3 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3987) RVT_1 PF00078.27 GBG41103.1 - 1.9e-28 99.5 0.0 2.8e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG41103.1 - 2.3e-15 56.4 1.0 6.9e-15 54.9 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG41103.1 - 4.7e-10 39.2 0.0 9.9e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG41103.1 - 2.4e-08 34.2 0.0 7.5e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG41103.1 - 1.3e-05 25.3 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger EFF-AFF PF14884.6 GBG41115.1 - 0.04 12.1 0.0 0.057 11.5 0.0 1.1 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen RVT_1 PF00078.27 GBG41130.1 - 3.1e-29 102.1 0.2 5.5e-29 101.3 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG41130.1 - 1.5e-14 54.2 0.0 3.5e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG41130.1 - 0.00039 20.5 0.4 0.0094 16.0 0.0 2.7 2 0 0 2 2 2 1 Integrase zinc binding domain DUF2385 PF09539.10 GBG41130.1 - 0.15 12.6 0.2 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) HSP20 PF00011.21 GBG41132.1 - 1e-27 96.3 0.0 1.7e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG41132.1 - 3.1e-07 29.8 0.2 7.7e-07 28.6 0.2 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA PBP1_TM PF14812.6 GBG41144.1 - 0.044 14.2 2.3 0.13 12.7 2.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_Tnp_4 PF13359.6 GBG41146.1 - 5.6e-31 107.3 0.0 7.6e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG41146.1 - 2.3e-15 56.8 0.0 3.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG41146.1 - 9.7e-06 25.4 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain RT_RNaseH PF17917.1 GBG41161.1 - 1.9e-22 79.5 0.0 3.1e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG41161.1 - 2.1e-20 72.6 0.0 3.8e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG41161.1 - 6.8e-12 45.3 0.1 1.4e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG41161.1 - 1.7e-10 41.2 0.0 4.2e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Jnk-SapK_ap_N PF09744.9 GBG41163.1 - 0.0037 17.5 3.2 0.0082 16.4 3.2 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 OB_Dis3 PF17849.1 GBG41163.1 - 0.047 13.7 0.1 0.088 12.9 0.1 1.4 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) TPR_MLP1_2 PF07926.12 GBG41163.1 - 1.4 9.0 8.8 1.7 8.7 7.6 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein RT_RNaseH_2 PF17919.1 GBG41170.1 - 4.5e-24 84.4 0.0 8.1e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG41170.1 - 1.8e-21 76.4 0.0 3e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG41170.1 - 2.1e-10 40.8 0.0 4.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Glyco_transf_5 PF08323.11 GBG41191.1 - 1.6e-25 90.2 0.0 2.3e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Dimer_Tnp_Tn5 PF02281.16 GBG41191.1 - 0.11 12.2 0.0 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Transposase Tn5 dimerisation domain gag-asp_proteas PF13975.6 GBG41199.1 - 7.4e-09 36.1 0.1 2.1e-08 34.6 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG41199.1 - 9.6e-07 29.4 0.1 2.5e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG41199.1 - 1e-06 28.5 0.1 1.8e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG41199.1 - 0.0059 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease MFMR_assoc PF16596.5 GBG41199.1 - 0.066 13.7 2.4 0.14 12.6 2.4 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR Peptidase_A3 PF02160.15 GBG41199.1 - 0.12 11.8 0.0 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) RT_RNaseH PF17917.1 GBG41205.1 - 4.2e-14 52.7 0.0 7.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG41205.1 - 5.5e-11 42.4 0.0 9.8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG41205.1 - 7e-11 42.1 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG41216.1 - 5.5e-32 110.6 0.0 9.3e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG41216.1 - 9.3e-14 51.5 0.0 1.5e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG41216.1 - 0.0082 15.8 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG41216.1 - 0.13 12.7 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain S100PBPR PF15427.6 GBG41216.1 - 5.2 6.2 7.8 7.8 5.6 7.8 1.1 1 0 0 1 1 1 0 S100P-binding protein N6_N4_Mtase PF01555.18 GBG41259.1 - 4.4e-07 29.9 0.0 7.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 DNA methylase CLIP1_ZNF PF16641.5 GBG41277.1 - 0.00066 19.5 0.1 0.0016 18.3 0.1 1.7 1 0 0 1 1 1 1 CLIP1 zinc knuckle RRM_1 PF00076.22 GBG41278.1 - 6.5e-08 32.3 0.0 7.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG41278.1 - 0.042 14.0 0.0 0.049 13.7 0.0 1.3 1 1 0 1 1 1 0 RNA recognition motif RNA_pol_Rpb5_N PF03871.14 GBG41301.1 - 3.5e-24 85.2 0.6 1.1e-23 83.5 0.3 1.8 1 1 1 2 2 2 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 GBG41301.1 - 6.2e-21 74.0 0.2 1.4e-20 72.9 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.12 GBG41301.1 - 0.004 17.2 0.0 0.0066 16.5 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease BAT2_N PF07001.11 GBG41303.1 - 0.43 11.0 26.4 0.39 11.2 9.4 2.1 2 0 0 2 2 2 0 BAT2 N-terminus Mucin PF01456.17 GBG41303.1 - 3 7.8 8.5 0.9 9.5 5.4 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein RAB3GAP2_N PF14655.6 GBG41313.1 - 0.12 11.6 0.0 0.13 11.5 0.0 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CSRNP_N PF16019.5 GBG41316.1 - 0.0041 17.1 1.8 0.0048 16.8 1.8 1.0 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus FAM60A PF15396.6 GBG41316.1 - 0.0065 16.5 5.0 0.0071 16.4 5.0 1.0 1 0 0 1 1 1 1 Protein Family FAM60A RNA_pol_3_Rpc31 PF11705.8 GBG41316.1 - 0.028 14.7 13.9 0.039 14.2 13.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 VIR_N PF15912.5 GBG41316.1 - 1.4 8.5 9.0 1.6 8.2 9.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal RT_RNaseH_2 PF17919.1 GBG41324.1 - 5.7e-31 106.5 0.0 1.1e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG41324.1 - 1.9e-26 92.4 0.1 3.6e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG41324.1 - 8.8e-17 61.4 0.0 2.1e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG41324.1 - 2.8e-15 56.2 0.1 6.3e-14 51.8 0.1 2.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG41324.1 - 0.0039 17.4 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger eIF-1a PF01176.19 GBG41324.1 - 0.025 14.4 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Chromo PF00385.24 GBG41324.1 - 0.056 13.4 0.9 0.099 12.6 0.1 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Chorismate_synt PF01264.21 GBG41332.1 - 7.8e-12 44.5 0.3 8.2e-12 44.5 0.3 1.0 1 0 0 1 1 1 1 Chorismate synthase RT_RNaseH_2 PF17919.1 GBG41335.1 - 8.5e-33 112.4 0.0 1.6e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG41335.1 - 2.2e-29 101.8 0.0 4.3e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG41335.1 - 9.6e-11 41.6 0.1 1.6e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG41337.1 - 4.5e-27 94.0 0.0 9.5e-27 93.0 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG41337.1 - 1.9e-20 73.1 0.0 4.3e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG41337.1 - 6e-12 45.6 0.1 8.4e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) COX_ARM PF06481.14 GBG41337.1 - 0.061 13.2 0.6 9.5 6.2 0.0 2.5 2 0 0 2 2 2 0 COX Aromatic Rich Motif DUF659 PF04937.15 GBG41368.1 - 0.00067 19.5 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG41374.1 - 0.00095 18.7 0.5 0.1 12.1 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG41395.1 - 1.5e-12 47.2 0.0 2.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG41395.1 - 6.3e-11 42.5 0.1 1.6e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain OSCP PF00213.18 GBG41397.1 - 3.2e-42 144.6 1.4 3.6e-42 144.4 1.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit RT_RNaseH_2 PF17919.1 GBG41400.1 - 1.9e-32 111.3 0.0 4e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG41400.1 - 9.7e-30 103.0 0.0 1.9e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG41400.1 - 3.3e-29 102.0 0.0 5.4e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG41400.1 - 2.4e-14 53.2 0.3 4.6e-14 52.3 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG41400.1 - 4.7e-11 42.9 0.5 9.1e-10 38.8 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain SAM_2 PF07647.17 GBG41411.1 - 4.9e-13 49.0 0.2 5.6e-13 48.8 0.2 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GBG41411.1 - 2.1e-11 44.1 0.3 2.4e-11 43.9 0.3 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 GBG41411.1 - 1.8e-09 37.4 0.1 2.2e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 GBG41411.1 - 5.9e-08 32.4 0.1 8.8e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 GBG41411.1 - 0.032 14.2 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GAT PF03127.14 GBG41435.1 - 3.1e-13 49.8 1.2 4.4e-13 49.3 1.2 1.2 1 0 0 1 1 1 1 GAT domain WXG100 PF06013.12 GBG41435.1 - 0.0021 18.3 1.4 0.0059 16.8 1.4 1.7 1 0 0 1 1 1 1 Proteins of 100 residues with WXG TraG_N PF07916.11 GBG41435.1 - 1.6 7.5 7.0 0.082 11.8 1.9 1.4 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Mucin-like PF16058.5 GBG41468.1 - 1.4 9.0 8.4 3.8 7.7 1.6 2.3 2 0 0 2 2 2 0 Mucin-like gag-asp_proteas PF13975.6 GBG41471.1 - 0.00013 22.4 0.0 0.00025 21.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG41471.1 - 0.0011 19.2 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG41471.1 - 0.0086 16.7 0.0 0.022 15.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG41471.1 - 0.05 13.4 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Corona_NS2 PF04753.12 GBG41471.1 - 0.15 12.6 0.0 0.26 11.9 0.0 1.4 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 rve PF00665.26 GBG41472.1 - 0.0053 16.9 0.0 0.0071 16.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG41472.1 - 0.013 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain PUF PF00806.19 GBG41472.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat FAM60A PF15396.6 GBG41489.1 - 8.7 6.3 16.4 26 4.7 16.4 1.9 1 1 0 1 1 1 0 Protein Family FAM60A RT_RNaseH PF17917.1 GBG41494.1 - 8.2e-30 103.2 0.0 2.1e-29 101.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG41494.1 - 6.2e-29 100.0 0.0 1.9e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG41494.1 - 4.8e-14 52.4 0.1 9.6e-14 51.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG41494.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2959 PF11172.8 GBG41494.1 - 0.019 15.1 0.1 0.051 13.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Myb_DNA-bind_4 PF13837.6 GBG41498.1 - 1.4e-06 28.5 3.6 1.1e-05 25.7 0.8 2.6 2 2 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG41498.1 - 0.093 13.1 0.5 0.67 10.3 0.1 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spectrin PF00435.21 GBG41498.1 - 0.96 10.0 3.5 7.4 7.1 0.3 2.2 2 0 0 2 2 2 0 Spectrin repeat DDE_1 PF03184.19 GBG41500.1 - 2.1e-11 43.8 0.1 3e-11 43.3 0.1 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG41507.1 - 7.4e-21 74.7 0.3 8.9e-21 74.4 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Orf78 PF06024.12 GBG41512.1 - 0.0049 17.2 0.5 0.011 16.0 0.1 1.7 1 1 0 2 2 2 1 Orf78 (ac78) DNA_pol_phi PF04931.13 GBG41512.1 - 0.022 12.9 20.6 0.028 12.5 20.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2722 PF10846.8 GBG41512.1 - 0.13 11.2 3.5 0.13 11.2 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Arf PF00025.21 GBG41515.1 - 7.6e-64 214.3 0.0 8.8e-64 214.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GBG41515.1 - 4.4e-10 39.2 0.1 1.8e-06 27.4 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GBG41515.1 - 6.1e-10 38.8 0.0 8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GBG41515.1 - 1.6e-07 31.5 0.0 2.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GBG41515.1 - 5.2e-07 29.4 0.0 6.2e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GBG41515.1 - 2.2e-06 27.2 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PAN_4 PF14295.6 GBG41532.1 - 5.1e-06 26.3 4.3 8e-06 25.7 4.3 1.4 1 0 0 1 1 1 1 PAN domain RT_RNaseH_2 PF17919.1 GBG41536.1 - 2.1e-31 107.9 0.0 6.3e-31 106.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG41536.1 - 1.4e-19 70.3 0.0 3.1e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG41536.1 - 9.8e-11 41.6 0.3 1.7e-10 40.8 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG41536.1 - 9.7e-08 32.5 0.0 2.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG41536.1 - 7e-06 26.6 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG41536.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG41536.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG41536.1 - 0.021 14.6 0.2 0.061 13.1 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG41538.1 - 3e-16 59.3 0.1 3.9e-15 55.7 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG41538.1 - 4.1e-16 59.2 0.0 6.8e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG41538.1 - 0.0007 19.8 0.0 0.0021 18.2 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger eIF-1a PF01176.19 GBG41538.1 - 0.0012 18.6 0.1 0.0029 17.4 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 rve_3 PF13683.6 GBG41538.1 - 0.03 14.1 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Chromo PF00385.24 GBG41538.1 - 0.065 13.1 1.1 0.095 12.6 0.1 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Dehydratase_MU PF02288.15 GBG41556.1 - 0.009 15.9 0.1 7.5 6.5 0.1 2.7 3 0 0 3 3 3 2 Dehydratase medium subunit BSP_II PF05432.11 GBG41556.1 - 1.5 8.4 11.4 2.2 7.9 11.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) GRP PF07172.11 GBG41556.1 - 2.8 8.7 18.7 6 7.6 18.7 1.6 1 0 0 1 1 1 0 Glycine rich protein family DUF3443 PF11925.8 GBG41557.1 - 0.052 12.4 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) CDC45 PF02724.14 GBG41597.1 - 0.024 12.9 6.8 0.025 12.9 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG41597.1 - 0.036 12.3 14.8 0.037 12.3 14.8 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG41597.1 - 0.056 12.0 12.4 0.071 11.7 12.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zip PF02535.22 GBG41597.1 - 0.22 10.7 1.4 0.25 10.5 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 GBG41597.1 - 0.32 9.4 12.1 0.34 9.3 12.1 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG41597.1 - 0.97 8.8 17.8 1.1 8.6 17.8 1.0 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG41597.1 - 1.7 7.9 13.4 1.9 7.8 13.4 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GBG41597.1 - 3.1 6.5 5.5 3.8 6.2 5.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NOA36 PF06524.12 GBG41597.1 - 5 6.4 21.9 6.7 5.9 21.9 1.1 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.13 GBG41597.1 - 6.5 6.8 14.8 7.5 6.6 14.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein FragX_IP PF05994.11 GBG41602.1 - 1.7e-66 224.9 4.0 1.8e-66 224.8 4.0 1.0 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family GRP PF07172.11 GBG41613.1 - 6.8 7.5 36.0 7.3 7.4 36.0 1.1 1 0 0 1 1 1 0 Glycine rich protein family Ammonium_transp PF00909.21 GBG41633.1 - 1.9e-124 415.4 36.8 2.4e-124 415.1 36.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Chromo PF00385.24 GBG41651.1 - 0.00082 19.2 0.0 0.0039 17.1 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF5069 PF16798.5 GBG41651.1 - 0.017 15.3 0.3 0.21 11.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) DNA_pack_N PF02500.15 GBG41651.1 - 2.7 7.8 4.8 0.86 9.4 0.1 2.1 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus PEP-utilisers_N PF05524.13 GBG41651.1 - 9.2 6.5 18.4 0.16 12.2 6.6 3.1 3 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal LMBR1 PF04791.16 GBG41651.1 - 9.7 5.0 9.7 18 4.0 9.6 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Glyco_hydro_4 PF02056.16 GBG41658.1 - 0.013 15.1 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Myb_DNA-bind_4 PF13837.6 GBG41667.1 - 0.00026 21.3 0.6 0.00052 20.3 0.2 1.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG41686.1 - 1.1e-32 113.4 0.0 2.3e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG41686.1 - 6.3e-30 103.2 0.0 2.7e-29 101.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG41686.1 - 1.1e-27 96.4 0.0 3.1e-27 94.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG41686.1 - 1.7e-17 63.2 0.9 3.7e-17 62.2 0.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG41686.1 - 3.1e-16 59.6 0.0 8.9e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG41686.1 - 0.00092 19.4 1.3 0.0019 18.4 0.2 2.1 2 0 0 2 2 2 1 H2C2 zinc finger Exonuc_VII_L PF02601.15 GBG41686.1 - 0.29 10.7 10.6 0.69 9.4 10.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 GBG41691.1 - 1.1e-05 25.5 25.9 0.0032 17.5 5.8 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 GBG41691.1 - 0.00067 19.6 9.1 0.00067 19.6 9.1 3.5 1 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 GBG41691.1 - 0.002 18.2 21.4 0.047 13.8 9.6 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 GBG41691.1 - 0.0024 16.6 10.0 0.0029 16.3 10.0 1.1 1 0 0 1 1 1 1 AAA domain Bacillus_HBL PF05791.11 GBG41691.1 - 0.0026 17.6 4.4 0.75 9.6 0.1 2.3 1 1 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) Fez1 PF06818.15 GBG41691.1 - 0.0037 17.8 12.6 0.0037 17.8 12.6 2.1 1 1 1 2 2 2 1 Fez1 Spc7 PF08317.11 GBG41691.1 - 0.005 15.8 22.8 0.028 13.3 13.4 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein MAD PF05557.13 GBG41691.1 - 0.0069 14.8 20.4 0.86 7.9 2.4 1.9 1 1 0 1 1 1 1 Mitotic checkpoint protein DUF1664 PF07889.12 GBG41691.1 - 0.0099 15.9 9.6 0.27 11.3 3.3 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) LPP PF04728.13 GBG41691.1 - 0.015 15.7 9.4 3.2 8.2 1.6 4.6 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Laminin_II PF06009.12 GBG41691.1 - 0.03 14.3 11.8 0.23 11.5 4.3 2.3 1 1 1 2 2 2 0 Laminin Domain II Golgin_A5 PF09787.9 GBG41691.1 - 0.038 13.5 21.3 7.7 5.9 21.1 2.2 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF948 PF06103.11 GBG41691.1 - 0.044 14.0 4.5 0.78 10.0 1.3 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) CCDC144C PF14915.6 GBG41691.1 - 0.067 12.3 19.4 0.065 12.3 7.2 2.5 1 1 2 3 3 3 0 CCDC144C protein coiled-coil region ATG16 PF08614.11 GBG41691.1 - 0.15 12.3 24.0 0.15 12.3 9.7 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.19 GBG41691.1 - 0.15 11.9 23.7 1.2 8.9 13.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CALCOCO1 PF07888.11 GBG41691.1 - 0.16 10.8 21.9 0.82 8.5 21.8 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3450 PF11932.8 GBG41691.1 - 0.16 11.2 16.4 0.37 10.0 2.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 GBG41691.1 - 0.16 12.0 2.7 1.4 8.9 0.4 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 GBG41691.1 - 0.2 11.4 18.8 0.021 14.6 8.7 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal KASH_CCD PF14662.6 GBG41691.1 - 0.27 11.1 23.2 0.26 11.1 13.4 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HrpB7 PF09486.10 GBG41691.1 - 0.4 11.1 13.1 5.7 7.3 9.3 2.9 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Phage_GP20 PF06810.11 GBG41691.1 - 0.56 10.0 13.2 0.18 11.6 0.3 3.4 1 1 2 3 3 3 0 Phage minor structural protein GP20 COG5 PF10392.9 GBG41691.1 - 0.64 10.2 7.4 0.91 9.7 0.2 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF641 PF04859.12 GBG41691.1 - 0.71 10.2 17.5 2.4 8.5 0.9 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) TMF_TATA_bd PF12325.8 GBG41691.1 - 0.71 10.1 25.8 0.3 11.3 8.8 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 GBG41691.1 - 0.72 9.9 17.0 0.77 9.8 3.6 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PKcGMP_CC PF16808.5 GBG41691.1 - 0.82 9.6 0.1 0.82 9.6 0.1 4.4 5 0 0 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase XLF PF09302.11 GBG41691.1 - 0.91 9.7 8.8 0.27 11.4 1.1 2.9 1 1 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Rop-like PF05082.13 GBG41691.1 - 1.1 9.1 6.1 4.7 7.1 0.1 3.1 3 1 0 3 3 3 0 Rop-like HAUS-augmin3 PF14932.6 GBG41691.1 - 1.2 8.7 18.9 0.26 10.8 3.2 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FAM76 PF16046.5 GBG41691.1 - 1.2 8.4 13.9 17 4.7 0.5 2.1 1 1 1 2 2 2 0 FAM76 protein TMPIT PF07851.13 GBG41691.1 - 1.3 8.2 12.3 0.47 9.7 3.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF16 PF01519.16 GBG41691.1 - 1.9 9.0 13.8 17 6.0 4.7 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 Lebercilin PF15619.6 GBG41691.1 - 2.4 7.8 27.9 0.75 9.4 14.6 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HAP1_N PF04849.13 GBG41691.1 - 2.6 7.2 25.4 0.9 8.7 14.5 2.4 1 1 0 2 2 2 0 HAP1 N-terminal conserved region Syntaxin-6_N PF09177.11 GBG41691.1 - 3.1 8.4 11.0 5.5 7.6 4.6 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 GBG41691.1 - 3.4 7.8 11.9 1.2 9.3 2.4 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 GBG41691.1 - 4 7.7 18.7 38 4.6 8.6 3.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Csm1_N PF18504.1 GBG41691.1 - 4.2 7.8 20.7 8 6.9 1.5 4.2 1 1 2 4 4 4 0 Csm1 N-terminal domain SlyX PF04102.12 GBG41691.1 - 4.6 7.9 17.8 6.7 7.4 1.6 4.2 1 1 3 4 4 4 0 SlyX USP8_interact PF08941.10 GBG41691.1 - 4.9 6.9 10.1 1.1 9.1 2.0 2.7 1 1 2 3 3 3 0 USP8 interacting YtxH PF12732.7 GBG41691.1 - 4.9 7.8 7.6 6.5e+02 0.9 7.6 2.8 1 1 0 1 1 1 0 YtxH-like protein DUF724 PF05266.14 GBG41691.1 - 7.4 6.3 17.5 8.5 6.2 6.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 GBG41691.1 - 7.6 6.0 14.3 20 4.6 14.3 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit ATP-synt_E PF05680.12 GBG41691.1 - 8.2 6.8 8.4 0.54 10.6 0.3 2.4 2 1 0 2 2 2 0 ATP synthase E chain DUF3499 PF12005.8 GBG41707.1 - 0.61 10.7 7.2 2.2 8.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) DUF1242 PF06842.12 GBG41709.1 - 1 9.3 6.2 2.3 8.1 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) KN17_SH3 PF18131.1 GBG41720.1 - 0.029 14.5 0.3 17 5.6 0.0 3.2 1 1 2 3 3 3 0 KN17 SH3-like C-terminal domain RFX1_trans_act PF04589.13 GBG41720.1 - 0.059 13.5 8.5 0.18 12.0 4.5 2.6 1 1 1 2 2 2 0 RFX1 transcription activation region Thioredoxin_6 PF13848.6 GBG41723.1 - 7.8e-09 35.7 0.0 8.9e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Baculo_E56 PF04639.12 GBG41723.1 - 0.093 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope TOM20_plant PF06552.12 GBG41730.1 - 6e-57 192.4 0.0 7.5e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.6 GBG41730.1 - 1.4e-09 37.5 0.1 0.0014 18.3 0.0 3.3 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 GBG41730.1 - 4.2e-07 29.6 1.8 0.031 14.4 0.4 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG41730.1 - 1.2e-06 28.1 0.7 0.017 14.9 0.4 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG41730.1 - 0.00022 21.8 0.3 0.97 10.4 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG41730.1 - 0.00073 20.1 0.3 4.1 8.1 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG41730.1 - 0.004 17.2 1.8 5.2 7.5 0.2 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG41730.1 - 0.011 15.6 0.7 3.9 7.5 0.0 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG41730.1 - 0.013 16.0 0.1 5.1 7.7 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG41730.1 - 0.023 15.1 0.3 6.4 7.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG41730.1 - 0.042 14.0 0.3 2.1 8.5 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 GBG41730.1 - 0.075 12.5 2.1 0.32 10.4 0.6 2.0 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 GBG41730.1 - 0.13 12.4 7.6 17 5.7 0.2 4.7 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG41730.1 - 0.26 11.6 3.0 5.1 7.5 0.6 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG41730.1 - 3.9 8.3 6.1 7.5 7.4 0.2 3.6 4 1 0 4 4 2 0 Tetratricopeptide repeat HATPase_c PF02518.26 GBG41749.1 - 1.3e-15 57.9 0.4 4.3e-15 56.2 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GBG41749.1 - 4.6e-12 46.1 0.9 7.3e-05 22.9 0.1 3.9 3 1 0 3 3 3 3 Response regulator receiver domain CbiC PF02570.15 GBG41749.1 - 0.004 16.8 0.2 0.19 11.4 0.0 2.2 2 0 0 2 2 2 1 Precorrin-8X methylmutase Toprim_N PF08275.11 GBG41770.1 - 0.00067 19.7 5.8 13 5.8 0.0 6.2 2 2 4 6 6 6 1 DNA primase catalytic core, N-terminal domain RTA1 PF04479.13 GBG41770.1 - 0.0028 17.3 13.0 35 3.9 0.0 7.2 4 2 4 8 8 8 0 RTA1 like protein PapC_C PF13953.6 GBG41770.1 - 0.0041 16.9 25.6 0.49 10.3 0.1 6.9 1 1 6 7 7 7 4 PapC C-terminal domain Methyltransf_1N PF02870.15 GBG41770.1 - 0.0072 17.1 3.8 3.7 8.4 0.2 4.1 2 1 1 3 3 3 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain SH3_19 PF18597.1 GBG41770.1 - 0.028 14.3 21.1 7.3 6.5 0.1 6.7 7 0 0 7 7 7 0 Myosin X N-terminal SH3 domain DdrB PF12747.7 GBG41770.1 - 2.6 7.9 16.2 22 4.9 0.4 5.5 1 1 7 8 8 8 0 DdrB-like protein Topoisom_bac PF01131.20 GBG41772.1 - 1.7e-14 53.7 0.0 1.8e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase rve PF00665.26 GBG41801.1 - 4.4e-10 39.8 0.0 7.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG41801.1 - 0.00043 20.1 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LON_substr_bdg PF02190.16 GBG41814.1 - 0.36 10.7 0.8 0.5 10.2 0.8 1.2 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain FXa_inhibition PF14670.6 GBG41837.1 - 0.021 15.1 0.5 0.021 15.1 0.5 1.1 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site RT_RNaseH_2 PF17919.1 GBG41849.1 - 1.9e-27 95.2 0.0 5.1e-27 93.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG41849.1 - 6.8e-27 93.8 0.1 1.3e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG41849.1 - 2.2e-10 40.4 0.7 3.1e-06 26.9 0.0 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG41849.1 - 3.8e-07 29.9 0.0 8.7e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG41849.1 - 7.5e-06 26.5 0.0 1.8e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG41849.1 - 0.00067 20.2 0.0 0.0022 18.5 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG41849.1 - 0.00076 19.3 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG41849.1 - 0.0015 18.3 0.0 0.011 15.5 0.0 2.2 2 1 0 2 2 2 1 Aspartyl protease Phage_GPO PF05929.11 GBG41849.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Beta_helix PF13229.6 GBG41861.1 - 1.8e-06 27.9 1.5 1.6e-05 24.8 0.3 2.3 1 1 1 2 2 2 1 Right handed beta helix region NosD PF05048.13 GBG41861.1 - 0.0038 16.5 0.0 0.0071 15.6 0.0 1.5 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 GBG41861.1 - 0.058 13.9 1.2 0.058 13.9 1.2 6.8 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Sld5 PF05916.11 GBG41871.1 - 6.1e-23 81.4 0.4 8.3e-23 80.9 0.4 1.2 1 0 0 1 1 1 1 GINS complex protein DUF4169 PF13770.6 GBG41893.1 - 0.05 13.9 4.0 0.15 12.4 4.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4169) DDE_Tnp_1 PF01609.21 GBG41899.1 - 2.9e-10 40.2 0.0 4.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain RVT_1 PF00078.27 GBG41904.1 - 1e-28 100.4 0.0 1.4e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG41904.1 - 6.9e-11 42.1 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG41904.1 - 8.1e-08 32.8 0.0 1.6e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG41904.1 - 1.6e-06 28.6 0.0 3.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG41904.1 - 0.0043 16.8 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG41904.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DnaJ PF00226.31 GBG41923.1 - 1.5e-12 47.4 0.2 1.2e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 DnaJ domain TTRAP PF14203.6 GBG41923.1 - 0.042 13.8 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein DUF4576 PF15144.6 GBG41948.1 - 1 9.3 3.5 1.5 8.8 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4576) SDA1 PF05285.12 GBG41948.1 - 4.1 6.7 14.0 5.2 6.4 14.0 1.0 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG41953.1 - 3.8e-36 124.7 0.1 6.9e-36 123.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG41953.1 - 2.2e-30 104.6 0.0 5e-29 100.3 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG41953.1 - 1.8e-29 102.1 0.2 3.4e-28 98.0 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG41953.1 - 6.9e-20 70.9 0.3 1.6e-19 69.8 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG41953.1 - 7.1e-17 61.7 0.0 2.5e-16 60.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG41953.1 - 0.00071 19.7 0.1 0.002 18.3 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Arc_PepC_II PF06847.11 GBG41953.1 - 0.25 11.9 2.9 51 4.5 1.3 4.0 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II RT_RNaseH_2 PF17919.1 GBG41967.1 - 7e-27 93.4 0.0 1.2e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG41967.1 - 7.5e-26 90.5 0.0 1.9e-25 89.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG41967.1 - 0.00039 20.0 0.0 0.00068 19.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG41967.1 - 0.0031 16.7 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF3138 PF11336.8 GBG41984.1 - 0.023 13.3 0.9 0.034 12.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Herpes_UL25 PF01499.16 GBG41984.1 - 3.4 6.1 9.8 8 4.9 9.8 1.6 1 0 0 1 1 1 0 Herpesvirus UL25 family L_lactis_ph-MCP PF06673.11 GBG41990.1 - 0.18 10.8 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Glyoxalase_4 PF13669.6 GBG42010.1 - 5.6e-20 71.6 0.0 8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 GBG42010.1 - 5.8e-12 45.9 0.0 8.1e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 GBG42010.1 - 3.2e-06 27.4 4.5 4.1e-05 23.8 1.0 1.8 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 GBG42010.1 - 0.063 14.1 0.0 0.11 13.3 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Chromo PF00385.24 GBG42015.1 - 2.1e-12 46.8 0.0 4.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Macoilin PF09726.9 GBG42016.1 - 0.082 11.5 4.2 0.09 11.3 4.2 1.0 1 0 0 1 1 1 0 Macoilin family DUF5401 PF17380.2 GBG42016.1 - 0.19 9.7 8.7 0.23 9.5 8.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) UQ_con PF00179.26 GBG42033.1 - 7.4e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nuc_N PF14448.6 GBG42033.1 - 0.011 15.5 0.2 0.02 14.7 0.2 1.4 1 0 0 1 1 1 0 Nuclease N terminal Trypsin PF00089.26 GBG42041.1 - 0.11 12.2 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Trypsin DUF4763 PF15960.5 GBG42074.1 - 0.0056 16.0 0.0 0.0081 15.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) SlyX PF04102.12 GBG42074.1 - 0.054 14.1 0.1 0.62 10.7 0.2 2.2 2 0 0 2 2 2 0 SlyX DHR10 PF18595.1 GBG42074.1 - 0.14 12.2 0.5 0.29 11.2 0.5 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain SRP-alpha_N PF04086.13 GBG42074.1 - 2.6 7.9 5.2 3.7 7.4 5.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Chromo PF00385.24 GBG42103.1 - 5.3e-05 23.1 0.0 8.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG42107.1 - 1.3e-16 60.4 0.2 5.7e-16 58.4 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG42107.1 - 2.1e-11 44.0 0.0 5.6e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG42107.1 - 7e-05 23.0 0.2 0.00015 21.9 0.2 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG42130.1 - 6.6e-28 96.7 0.0 1e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG42130.1 - 1.9e-16 60.3 0.0 2.8e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG42130.1 - 3.1e-16 59.6 0.0 5.2e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GYF PF02213.16 GBG42143.1 - 0.0078 15.9 0.2 0.19 11.4 0.0 3.1 4 0 0 4 4 4 1 GYF domain DUF5549 PF17703.1 GBG42143.1 - 2.5 7.7 4.8 3.5 7.2 4.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5549) FoP_duplication PF13865.6 GBG42143.1 - 5.6 7.6 11.1 8.8 7.0 11.1 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 CPSF100_C PF13299.6 GBG42157.1 - 9.9 6.3 11.2 11 6.1 11.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal LEA_2 PF03168.13 GBG42162.1 - 1.7e-27 95.9 0.0 3.8e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Late embryogenesis abundant protein Sif PF06767.11 GBG42162.1 - 0.099 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Sif protein Retrotrans_gag PF03732.17 GBG42173.1 - 0.0099 16.1 3.5 0.021 15.1 0.0 2.9 3 1 0 3 3 3 1 Retrotransposon gag protein HAUS6_N PF14661.6 GBG42173.1 - 0.37 10.3 5.3 0.14 11.7 0.4 2.3 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Myb_DNA-bind_4 PF13837.6 GBG42186.1 - 1.9e-08 34.6 3.4 2.9e-08 34.0 3.4 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG42186.1 - 0.0034 17.4 3.3 0.007 16.4 3.3 1.5 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG42186.1 - 0.17 12.1 0.9 0.6 10.4 0.9 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain zf-CCHC PF00098.23 GBG42200.1 - 0.023 14.7 1.9 0.039 14.0 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Dehalogenase PF13486.6 GBG42208.1 - 0.0014 18.1 1.0 0.0016 17.9 1.0 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit OmpH PF03938.14 GBG42208.1 - 0.5 10.7 11.4 0.77 10.1 11.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Borrelia_P83 PF05262.11 GBG42208.1 - 1 7.8 8.0 1.3 7.4 8.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein EMC3_TMCO1 PF01956.16 GBG42208.1 - 5.2 6.8 5.1 7.2 6.3 5.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Topo_Zn_Ribbon PF08272.11 GBG42216.1 - 0.02 14.5 0.3 0.042 13.5 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG42216.1 - 0.055 13.6 0.6 0.098 12.8 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG42223.1 - 3.6e-06 26.6 0.0 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LMSTEN PF07988.12 GBG42223.1 - 0.089 12.3 0.8 11 5.6 0.7 2.3 2 0 0 2 2 2 0 LMSTEN motif RT_RNaseH PF17917.1 GBG42229.1 - 3.8e-30 104.3 0.0 6.6e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG42229.1 - 3.4e-28 97.6 0.0 6e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG42229.1 - 7.6e-17 61.6 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG42229.1 - 1.3e-16 60.4 0.8 2.6e-16 59.5 0.8 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG42229.1 - 0.0012 19.1 1.2 0.027 14.7 0.3 2.6 2 0 0 2 2 2 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG42229.1 - 0.06 13.0 0.1 0.095 12.3 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-CCHC PF00098.23 GBG42242.1 - 4.5e-07 29.7 2.3 6.9e-07 29.1 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG42242.1 - 0.15 11.8 0.5 0.24 11.1 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG42242.1 - 0.24 11.3 4.3 0.38 10.6 4.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Tachystatin_A PF11406.8 GBG42250.1 - 0.99 9.5 3.7 2.6 8.2 3.3 1.9 2 0 0 2 2 2 0 Antimicrobial peptide tachystatin A Sporozoite_P67 PF05642.11 GBG42250.1 - 2.3 6.2 5.7 3.1 5.8 5.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LMBR1 PF04791.16 GBG42253.1 - 0.36 9.7 2.1 0.48 9.3 2.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LOH1CR12 PF10158.9 GBG42253.1 - 1.6 8.7 8.5 1.1 9.2 0.3 2.3 2 0 0 2 2 2 0 Tumour suppressor protein RVT_1 PF00078.27 GBG42268.1 - 2.1e-27 96.1 0.0 3.9e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG42268.1 - 4e-20 71.7 0.0 8.4e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG42268.1 - 6.1e-07 29.7 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase UAE_UbL PF14732.6 GBG42268.1 - 0.058 14.0 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Glyco_transf_5 PF08323.11 GBG42277.1 - 9.9e-43 146.6 0.0 1.3e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain PCI PF01399.27 GBG42279.1 - 1.7e-15 57.4 0.1 6.6e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain SPOUT_MTase PF02590.17 GBG42279.1 - 0.026 14.5 0.2 0.058 13.4 0.0 1.6 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase TPR_1 PF00515.28 GBG42279.1 - 0.065 13.1 2.1 3.4 7.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG42279.1 - 0.31 11.3 0.8 2.7 8.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.6 GBG42291.1 - 3.1e-08 33.9 0.6 3.1e-08 33.9 0.6 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG42291.1 - 0.88 9.7 4.4 0.24 11.5 1.6 1.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RT_RNaseH PF17917.1 GBG42305.1 - 3.6e-23 81.8 0.0 9.3e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG42305.1 - 2.6e-15 56.3 0.7 6.2e-15 55.1 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG42305.1 - 1.2e-14 54.2 0.0 3e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG42305.1 - 7e-09 35.9 0.0 2.2e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain SbcD_C PF12320.8 GBG42305.1 - 0.03 14.6 0.0 7.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain zf-CCHC PF00098.23 GBG42307.1 - 0.012 15.7 1.8 0.029 14.5 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle RasGEF_N PF00618.20 GBG42307.1 - 0.18 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 RasGEF N-terminal motif gag-asp_proteas PF13975.6 GBG42320.1 - 2.5e-05 24.8 0.1 5.9e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG42320.1 - 0.0039 17.8 0.3 0.0088 16.7 0.1 1.7 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG42320.1 - 0.01 15.6 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG42320.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG42333.1 - 2.2e-25 89.5 0.0 4e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG42333.1 - 1.4e-16 60.3 0.2 1.1e-15 57.4 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG42333.1 - 6.3e-14 52.2 0.0 1.5e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF3417 PF11897.8 GBG42333.1 - 0.00024 21.5 0.5 0.001 19.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3417) zf-H2C2 PF09337.10 GBG42333.1 - 0.00051 20.2 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF5095 PF17016.5 GBG42333.1 - 0.1 12.3 1.4 0.91 9.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) MSP1_C PF07462.11 GBG42333.1 - 1.5 7.4 5.1 0.32 9.6 0.9 1.9 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Presenilin PF01080.17 GBG42338.1 - 2.8 6.6 17.2 3.7 6.2 17.2 1.1 1 0 0 1 1 1 0 Presenilin Prothymosin PF03247.14 GBG42338.1 - 4.7 7.7 62.7 3.3 8.2 12.9 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family SAPS PF04499.15 GBG42338.1 - 9 4.9 15.6 11 4.7 15.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-RVT PF13966.6 GBG42341.1 - 5.8e-07 30.1 7.5 2e-06 28.4 7.5 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVP_2 PF08284.11 GBG42347.1 - 0.0042 16.8 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG42347.1 - 0.075 13.7 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Lipin_mid PF16876.5 GBG42347.1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Retrotrans_gag PF03732.17 GBG42347.1 - 0.15 12.4 0.2 0.27 11.6 0.2 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Bap31_Bap29_C PF18035.1 GBG42350.1 - 0.013 15.4 3.6 0.055 13.5 3.6 2.1 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain NPV_P10 PF05531.12 GBG42350.1 - 0.06 13.8 0.9 0.18 12.3 0.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein adh_short PF00106.25 GBG42350.1 - 0.061 12.8 2.1 0.11 12.0 2.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 GBG42350.1 - 0.16 11.9 0.5 0.42 10.5 0.5 1.7 1 0 0 1 1 1 0 KR domain Sec8_exocyst PF04048.14 GBG42350.1 - 2 8.3 8.3 0.075 12.9 0.9 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain RabGAP-TBC PF00566.18 GBG42350.1 - 2.5 7.7 4.6 0.31 10.6 0.4 1.6 2 0 0 2 2 2 0 Rab-GTPase-TBC domain RVT_1 PF00078.27 GBG42357.1 - 1.1e-30 106.9 0.1 1.7e-30 106.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG42357.1 - 1.3e-24 86.1 0.0 3e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG42357.1 - 4.6e-23 81.5 0.0 7.9e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HSP70 PF00012.20 GBG42362.1 - 3.1e-97 326.2 0.0 4.8e-97 325.6 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein TIM PF00121.18 GBG42362.1 - 7.6e-21 74.6 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG42362.1 - 3.9e-06 25.9 0.0 5.4e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Myb_DNA-bind_5 PF13873.6 GBG42362.1 - 0.038 14.1 2.3 0.086 12.9 2.3 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG42362.1 - 0.073 13.5 0.9 0.19 12.1 0.9 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Trypan_PARP PF05887.11 GBG42375.1 - 5.1 7.1 12.1 6.2 6.8 6.7 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Dimer_Tnp_hAT PF05699.14 GBG42414.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region rve PF00665.26 GBG42432.1 - 7.4e-13 48.7 0.0 2.4e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG42432.1 - 2.6e-12 47.0 0.0 5.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG42432.1 - 3.1e-12 46.4 0.0 6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG42432.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.4 3 0 0 3 3 3 0 Integrase zinc binding domain Exo_endo_phos PF03372.23 GBG42439.1 - 6e-12 45.6 0.1 1.4e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG42439.1 - 2.5e-05 24.1 0.0 7.7e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG42445.1 - 0.00031 20.5 1.0 0.0005 19.8 1.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Glyco_transf_5 PF08323.11 GBG42457.1 - 3.9e-67 226.5 0.0 6.2e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG42457.1 - 5e-09 35.9 0.0 7.8e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG42457.1 - 9.6e-08 32.5 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG42457.1 - 0.056 13.4 0.1 11 6.0 0.2 2.4 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Carb_kinase PF01256.17 GBG42457.1 - 0.14 11.6 0.0 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate kinase Tom22 PF04281.13 GBG42464.1 - 0.17 11.7 3.8 1.1 9.1 1.7 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Vma12 PF11712.8 GBG42468.1 - 1.3e-09 38.3 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATPase_gene1 PF09527.10 GBG42468.1 - 0.012 15.8 2.1 0.019 15.1 2.1 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter THOC7 PF05615.13 GBG42468.1 - 0.038 14.3 0.4 0.065 13.5 0.4 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 HSP20 PF00011.21 GBG42469.1 - 1.2e-29 102.5 0.1 1.7e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG42469.1 - 1.9e-09 36.9 0.1 4.9e-09 35.6 0.1 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 GBG42469.1 - 0.15 12.2 0.0 1.6 8.9 0.0 2.1 2 0 0 2 2 2 0 FKBP26_C-terminal Usp PF00582.26 GBG42473.1 - 0.087 13.3 4.4 0.11 13.0 4.4 1.1 1 0 0 1 1 1 0 Universal stress protein family NOA36 PF06524.12 GBG42473.1 - 0.11 11.8 13.3 0.11 11.8 13.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4820 PF16091.5 GBG42473.1 - 0.12 11.7 2.1 0.12 11.8 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SDA1 PF05285.12 GBG42473.1 - 0.16 11.4 13.2 0.15 11.4 13.2 1.0 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 GBG42473.1 - 0.26 10.9 14.2 0.24 10.9 14.2 1.1 1 0 0 1 1 1 0 PPP4R2 Rad54_N PF08658.10 GBG42473.1 - 0.33 11.1 3.9 0.39 10.9 3.9 1.2 1 0 0 1 1 1 0 Rad54 N terminal FAM176 PF14851.6 GBG42473.1 - 0.39 10.4 10.1 0.56 9.9 10.1 1.3 1 0 0 1 1 1 0 FAM176 family SspB PF04386.13 GBG42473.1 - 0.73 9.7 6.7 0.9 9.4 6.7 1.1 1 0 0 1 1 1 0 Stringent starvation protein B Sporozoite_P67 PF05642.11 GBG42473.1 - 1.4 7.0 5.2 1.1 7.2 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 GBG42473.1 - 1.7 6.9 13.7 1.8 6.7 13.7 1.1 1 0 0 1 1 1 0 CDC45-like protein MukE PF04288.13 GBG42473.1 - 3.2 6.6 6.4 4.2 6.2 6.4 1.1 1 0 0 1 1 1 0 MukE-like family Phage_Gp23 PF10669.9 GBG42473.1 - 4.2 7.7 9.2 6 7.2 9.2 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Retrotrans_gag PF03732.17 GBG42475.1 - 0.0012 19.1 2.7 0.0029 17.9 0.2 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG42475.1 - 0.0066 16.2 1.0 0.017 14.9 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Lipin_mid PF16876.5 GBG42475.1 - 0.044 13.9 0.5 0.41 10.8 0.0 2.5 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain CENP-K PF11802.8 GBG42475.1 - 0.053 13.1 2.4 0.11 12.1 2.4 1.4 1 1 0 1 1 1 0 Centromere-associated protein K RVT_1 PF00078.27 GBG42487.1 - 1.7e-32 112.8 0.0 2.8e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG42487.1 - 1.7e-06 28.6 1.8 5e-06 27.1 1.8 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase NOA36 PF06524.12 GBG42489.1 - 0.97 8.7 8.0 1 8.6 8.0 1.1 1 0 0 1 1 1 0 NOA36 protein MCD PF05292.11 GBG42493.1 - 0.044 13.4 0.5 0.09 12.3 0.1 1.6 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain STG PF15809.5 GBG42493.1 - 0.21 11.6 0.3 0.24 11.4 0.3 1.1 1 0 0 1 1 1 0 Simian taste bud-specific gene product family DUF4164 PF13747.6 GBG42493.1 - 0.24 11.7 6.3 5.8 7.3 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Cep57_MT_bd PF06657.13 GBG42493.1 - 0.27 11.7 5.0 9 6.8 0.2 3.2 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 MciZ PF13072.6 GBG42493.1 - 5 7.0 5.9 10 6.0 0.0 2.9 2 1 1 3 3 3 0 Mother cell inhibitor of FtsZ DUF4407 PF14362.6 GBG42500.1 - 0.13 11.6 11.6 0.26 10.6 11.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNApol_Exo PF18136.1 GBG42500.1 - 0.73 8.9 8.0 0.32 10.1 4.9 1.7 1 1 1 2 2 2 0 DNA mitochondrial polymerase exonuclease domain FAM76 PF16046.5 GBG42500.1 - 2.5 7.4 11.9 4 6.7 11.9 1.3 1 0 0 1 1 1 0 FAM76 protein MDM10 PF12519.8 GBG42500.1 - 3.4 6.4 4.5 5 5.9 4.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 AAA_13 PF13166.6 GBG42500.1 - 6.3 5.3 13.6 8.9 4.8 13.6 1.1 1 0 0 1 1 1 0 AAA domain Glycos_transf_1 PF00534.20 GBG42505.1 - 1.2e-18 67.2 0.0 2.3e-18 66.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG42505.1 - 1.8e-14 54.3 0.0 2.8e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GBG42507.1 - 9e-19 67.6 0.0 1.8e-18 66.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG42507.1 - 1.4e-14 54.7 0.0 2.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 WD40 PF00400.32 GBG42525.1 - 0.026 15.4 0.1 0.072 14.0 0.1 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat Sigma70_ner PF04546.13 GBG42525.1 - 0.39 10.6 9.7 0.54 10.1 9.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 GBG42525.1 - 0.78 7.8 21.6 1.1 7.2 21.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG42525.1 - 0.97 8.8 19.9 1.3 8.3 19.9 1.1 1 0 0 1 1 1 0 SDA1 CNDH2_C PF16858.5 GBG42525.1 - 1.7 8.5 4.5 2.5 7.9 4.5 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Mpp10 PF04006.12 GBG42525.1 - 1.7 7.0 11.1 2.3 6.6 11.1 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 GBG42525.1 - 2.5 6.3 10.4 3.6 5.8 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG42525.1 - 4 6.7 23.4 6.1 6.1 23.4 1.3 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 GBG42525.1 - 9.6 5.1 11.0 12 4.8 11.0 1.1 1 0 0 1 1 1 0 Pes-10 gag-asp_proteas PF13975.6 GBG42546.1 - 4.2e-09 36.9 0.0 7.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG42546.1 - 1.4e-08 35.2 0.0 2.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG42546.1 - 1.1e-06 28.4 0.0 2.9e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG42546.1 - 3.1e-06 27.0 0.0 4.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG42547.1 - 6.9e-05 23.0 2.5 0.0002 21.6 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein FAT PF02259.23 GBG42547.1 - 0.016 14.4 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 FAT domain DUF4618 PF15397.6 GBG42547.1 - 0.11 11.9 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Med4 PF10018.9 GBG42547.1 - 0.37 10.4 2.8 0.86 9.2 0.1 2.4 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 HIP1_clath_bdg PF16515.5 GBG42547.1 - 0.83 10.3 4.3 1.6 9.4 1.5 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pkinase PF00069.25 GBG42555.1 - 8.3e-21 74.5 0.0 1.9e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG42555.1 - 1.3e-16 60.7 0.0 3.1e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG42555.1 - 6.3e-08 33.2 5.8 0.00023 21.9 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Kinase-like PF14531.6 GBG42555.1 - 0.23 10.7 3.9 0.8 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like GvpK PF05121.12 GBG42555.1 - 0.65 10.1 3.1 1.6 8.8 3.1 1.6 1 0 0 1 1 1 0 Gas vesicle protein K MbeB_N PF04837.12 GBG42555.1 - 9.5 6.6 9.6 2.7 8.4 1.9 2.5 2 0 0 2 2 2 0 MbeB-like, N-term conserved region UCH PF00443.29 GBG42572.1 - 7.6e-13 48.5 0.0 8.1e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG42572.1 - 2.3e-06 27.5 0.0 2.5e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3824 PF12868.7 GBG42585.1 - 1.9 9.1 4.3 1.6 9.4 2.1 1.9 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) DUF3824 PF12868.7 GBG42603.1 - 1.9 9.1 4.3 1.6 9.4 2.1 1.9 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) WD40_alt PF14077.6 GBG42619.1 - 0.11 12.4 0.0 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif FAM76 PF16046.5 GBG42619.1 - 0.22 10.8 7.1 0.26 10.6 7.1 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4131 PF13567.6 GBG42629.1 - 0.11 12.1 1.2 0.8 9.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RT_RNaseH_2 PF17919.1 GBG42638.1 - 1.3e-35 121.4 0.1 1.9e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG42638.1 - 8.5e-30 103.1 0.1 1.3e-29 102.6 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase B9-C2 PF07162.11 GBG42638.1 - 0.11 12.7 0.0 14 5.8 0.1 2.2 1 1 1 2 2 2 0 Ciliary basal body-associated, B9 protein PI3Ka PF00613.20 GBG42638.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Apidaecin PF00807.17 GBG42654.1 - 3.8 7.7 6.5 0.73 10.0 1.8 2.2 2 0 0 2 2 2 0 Apidaecin DUF4169 PF13770.6 GBG42662.1 - 0.05 13.9 4.0 0.15 12.4 4.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4169) RT_RNaseH_2 PF17919.1 GBG42670.1 - 1.2e-25 89.4 0.0 3.3e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG42670.1 - 1.2e-22 80.2 0.0 3.4e-22 78.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG42670.1 - 2.5e-19 69.7 0.1 4.8e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG42670.1 - 3.9e-19 68.5 0.4 1.7e-18 66.4 0.3 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG42670.1 - 5.2e-08 33.1 0.0 1.6e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG42670.1 - 4e-07 30.6 0.0 1.1e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG42670.1 - 4.6e-07 30.3 0.0 1.4e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG42670.1 - 2e-05 24.4 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG42670.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG42670.1 - 0.005 17.1 0.7 0.031 14.5 0.1 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG42670.1 - 0.046 13.9 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger SPOB_a PF14689.6 GBG42675.1 - 5.9 6.7 27.1 6 6.6 0.1 5.9 5 1 2 7 7 7 0 Sensor_kinase_SpoOB-type, alpha-helical domain RVT_1 PF00078.27 GBG42688.1 - 3.5e-30 105.2 0.0 5.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG42688.1 - 0.0025 17.4 0.2 0.0045 16.5 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG42688.1 - 0.027 14.3 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF4360 PF14273.6 GBG42699.1 - 1.1e-36 126.3 0.0 1.3e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG42717.1 - 1.5e-27 95.6 0.0 4.7e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG42717.1 - 3.5e-27 95.4 0.3 6.1e-27 94.6 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG42717.1 - 5.5e-22 78.1 0.0 1.5e-20 73.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG42717.1 - 8.2e-19 67.9 0.0 2.2e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG42717.1 - 5.1e-09 36.1 0.1 1.3e-08 34.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain USP8_dimer PF08969.11 GBG42717.1 - 0.02 15.1 0.1 0.02 15.1 0.1 2.2 3 0 0 3 3 3 0 USP8 dimerisation domain rve_3 PF13683.6 GBG42717.1 - 0.047 13.5 0.0 0.16 11.7 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Peptidase_C48 PF02902.19 GBG42722.1 - 4.8e-21 75.6 0.0 8.9e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SbmA_BacA PF05992.12 GBG42722.1 - 0.2 11.0 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 SbmA/BacA-like family Tetraspanin PF00335.20 GBG42729.1 - 1.9e-05 24.5 15.4 3.2e-05 23.8 7.6 2.1 1 1 0 2 2 2 2 Tetraspanin family Mem_trans PF03547.18 GBG42734.1 - 2.1e-30 105.4 2.0 3e-30 104.9 2.0 1.2 1 0 0 1 1 1 1 Membrane transport protein DUF4187 PF13821.6 GBG42760.1 - 0.0011 18.7 1.5 0.0032 17.2 1.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Lipin_mid PF16876.5 GBG42760.1 - 0.019 15.1 0.3 0.073 13.2 0.0 2.1 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Retrotrans_gag PF03732.17 GBG42760.1 - 0.075 13.3 3.2 0.16 12.3 0.1 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein Orai-1 PF07856.12 GBG42769.1 - 0.16 11.7 0.1 0.23 11.1 0.1 1.1 1 0 0 1 1 1 0 Mediator of CRAC channel activity zf-CCHC PF00098.23 GBG42775.1 - 9.6e-07 28.6 1.5 2e-06 27.6 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL25 PF01499.16 GBG42775.1 - 0.072 11.6 5.8 1.2 7.6 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family zf-CCHC_2 PF13696.6 GBG42775.1 - 0.086 12.7 1.7 0.2 11.5 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4294 PF14127.6 GBG42775.1 - 0.46 10.4 4.7 0.42 10.5 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) DUF659 PF04937.15 GBG42784.1 - 2.7e-39 134.5 0.0 4.6e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pkinase PF00069.25 GBG42796.1 - 6.4e-34 117.5 0.0 3.1e-33 115.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG42796.1 - 2e-30 106.0 0.0 8.6e-23 80.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GBG42796.1 - 0.0018 18.3 0.0 0.089 12.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG42796.1 - 0.092 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RVP_2 PF08284.11 GBG42803.1 - 2.7e-06 27.2 0.0 5.5e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG42803.1 - 3.8e-06 27.4 0.0 7.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG42803.1 - 1.1e-05 26.0 0.0 2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG42803.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG42803.1 - 0.00029 20.6 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG42814.1 - 0.00054 20.2 0.4 0.00054 20.2 0.4 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG42814.1 - 0.0061 16.3 0.7 0.021 14.6 0.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DivIC PF04977.15 GBG42814.1 - 2.2 8.1 8.8 2.2 8.1 7.5 1.7 1 1 0 1 1 1 0 Septum formation initiator TAF4 PF05236.14 GBG42814.1 - 4.2 7.0 13.1 0.35 10.6 8.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family DUF4337 PF14235.6 GBG42814.1 - 7.1 6.7 7.0 13 5.9 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RT_RNaseH_2 PF17919.1 GBG42821.1 - 1.9e-24 85.6 0.0 3.6e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG42821.1 - 1.1e-22 80.2 0.0 1.9e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG42821.1 - 1e-08 35.0 0.1 1.7e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PaaX_C PF08223.11 GBG42821.1 - 0.12 12.7 0.2 0.86 9.9 0.0 2.3 2 1 1 3 3 3 0 PaaX-like protein C-terminal domain GIY-YIG PF01541.24 GBG42825.1 - 7.9e-06 26.1 1.0 1.8e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 GIY-YIG catalytic domain HTH_28 PF13518.6 GBG42825.1 - 0.067 13.3 0.0 0.27 11.4 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain Borrelia_REV PF03978.13 GBG42829.1 - 0.01 15.8 0.4 0.028 14.4 0.1 1.8 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein Retrotrans_gag PF03732.17 GBG42829.1 - 1.5 9.1 8.1 0.75 10.1 1.4 3.2 2 1 1 3 3 3 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG42847.1 - 9.6e-07 28.6 1.5 2e-06 27.6 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL25 PF01499.16 GBG42847.1 - 0.072 11.6 5.8 1.2 7.6 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family zf-CCHC_2 PF13696.6 GBG42847.1 - 0.086 12.7 1.7 0.2 11.5 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4294 PF14127.6 GBG42847.1 - 0.46 10.4 4.7 0.42 10.5 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) TFIIA PF03153.13 GBG42852.1 - 0.52 10.2 10.9 0.7 9.8 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DnaJ PF00226.31 GBG42856.1 - 6.5e-11 42.2 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain RVP_2 PF08284.11 GBG42884.1 - 0.0016 18.2 0.0 0.0052 16.6 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG42884.1 - 0.0024 18.5 0.0 0.076 13.7 0.0 2.2 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG42884.1 - 0.0034 17.9 0.0 0.016 15.7 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG42884.1 - 0.0068 16.2 0.0 0.015 15.1 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease DUF5395 PF17373.2 GBG42884.1 - 0.084 13.5 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5395) BDV_P10 PF06515.11 GBG42888.1 - 7.4 6.7 10.1 7.5 6.7 2.9 2.5 1 1 2 3 3 3 0 Borna disease virus P10 protein Pkinase PF00069.25 GBG42895.1 - 1.7e-08 34.2 0.0 2e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG42895.1 - 7.2e-07 28.7 0.0 6.6e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase NAD_binding_1 PF00175.21 GBG42900.1 - 3.1e-12 47.1 0.0 1.6e-11 44.8 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Cortex-I_coil PF09304.10 GBG42931.1 - 0.015 15.5 4.6 0.026 14.7 4.0 1.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil rve PF00665.26 GBG42945.1 - 6.8e-11 42.4 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG42959.1 - 8.6e-14 51.6 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PEPCK_ATP PF01293.20 GBG42960.1 - 1.4e-24 86.6 0.0 1.6e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase RT_RNaseH_2 PF17919.1 GBG42982.1 - 2.1e-26 91.9 0.0 4.5e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG42982.1 - 1.2e-24 86.6 0.0 2.2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG42982.1 - 5.1e-13 48.9 0.1 1.5e-12 47.4 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG42982.1 - 0.041 14.1 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RNR_Alpha PF17975.1 GBG42982.1 - 0.58 10.7 5.1 2.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain CLZ PF16526.5 GBG42982.1 - 1.7 9.1 6.3 0.18 12.1 0.9 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels rve PF00665.26 GBG42986.1 - 2.6e-11 43.7 0.0 6.9e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG42986.1 - 9.8e-10 38.2 0.0 2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG42991.1 - 4.5e-09 36.5 0.0 9.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG42991.1 - 5.6e-06 26.4 2.6 9.4e-06 25.6 2.6 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Tudor-knot PF11717.8 GBG42991.1 - 0.052 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Yae1_N PF09811.9 GBG43019.1 - 2.3e-10 40.0 28.0 0.038 13.7 0.0 11.0 8 2 4 12 12 12 5 Essential protein Yae1, N terminal Yae1_N PF09811.9 GBG43021.1 - 5.2e-05 22.9 61.5 0.25 11.1 4.9 10.7 8 3 5 13 13 13 6 Essential protein Yae1, N terminal RT_RNaseH_2 PF17919.1 GBG43063.1 - 3.9e-33 113.5 0.0 8.8e-33 112.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG43063.1 - 4.6e-30 104.0 0.2 9.2e-30 103.0 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG43063.1 - 4.7e-18 65.1 0.1 9.3e-18 64.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG43063.1 - 2.8e-15 56.5 0.0 7.3e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG43072.1 - 6.5e-36 123.9 0.1 1.1e-35 123.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG43072.1 - 1.3e-29 102.2 0.0 2.9e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG43072.1 - 2.6e-29 101.6 0.0 5.3e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2959 PF11172.8 GBG43072.1 - 0.13 12.3 0.0 0.53 10.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Integrase_H2C2 PF17921.1 GBG43140.1 - 2.1e-16 59.7 2.7 3.2e-16 59.2 0.4 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG43140.1 - 1.2e-13 51.3 0.1 2.1e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG43140.1 - 6.4e-10 39.3 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG43140.1 - 2.7e-08 33.7 0.0 5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG43140.1 - 7.2e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG43140.1 - 0.011 16.0 0.2 0.03 14.6 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Jnk-SapK_ap_N PF09744.9 GBG43153.1 - 0.0037 17.5 3.2 0.0082 16.4 3.2 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 OB_Dis3 PF17849.1 GBG43153.1 - 0.047 13.7 0.1 0.088 12.9 0.1 1.4 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) TPR_MLP1_2 PF07926.12 GBG43153.1 - 1.4 9.0 8.8 1.7 8.7 7.6 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein RT_RNaseH PF17917.1 GBG43155.1 - 2.2e-22 79.3 0.0 3.6e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG43155.1 - 5.8e-21 74.4 0.0 1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG43155.1 - 6.7e-12 45.3 0.1 1.6e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG43155.1 - 1.8e-10 41.1 0.0 4.9e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Imm32 PF15566.6 GBG43182.1 - 0.036 13.9 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 32 USP8_interact PF08941.10 GBG43182.1 - 0.045 13.6 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 USP8 interacting DDE_Tnp_4 PF13359.6 GBG43195.1 - 2.6e-14 53.2 0.0 7.2e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG43195.1 - 8e-08 32.1 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG43195.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain zf-CCHC PF00098.23 GBG43200.1 - 0.0069 16.4 0.4 0.014 15.5 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG43200.1 - 0.17 11.6 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle GMC_oxred_C PF05199.13 GBG43200.1 - 6.3 7.3 5.9 2.3 8.8 0.2 2.1 2 0 0 2 2 2 0 GMC oxidoreductase RT_RNaseH PF17917.1 GBG43213.1 - 5.4e-22 78.1 0.0 8.6e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG43213.1 - 1.1e-21 76.8 0.0 1.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG43213.1 - 5.5e-21 74.4 0.3 1.2e-20 73.4 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG43213.1 - 1.5e-07 31.6 0.0 4.8e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG43213.1 - 0.056 13.7 2.3 0.063 13.5 0.1 2.2 1 1 1 2 2 2 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG43222.1 - 1.1e-24 86.3 0.0 2.3e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG43222.1 - 1.5e-20 73.4 0.0 2.7e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Leader_Trp PF08255.11 GBG43222.1 - 0.13 12.3 0.9 0.34 11.0 0.9 1.7 1 0 0 1 1 1 0 Trp-operon Leader Peptide Lipoxygenase PF00305.19 GBG43227.1 - 1.7e-121 406.9 0.2 9.4e-116 387.8 0.0 2.5 1 1 1 2 2 2 2 Lipoxygenase DUF4075 PF13294.6 GBG43227.1 - 0.14 12.3 0.1 0.49 10.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) RT_RNaseH_2 PF17919.1 GBG43234.1 - 1.9e-29 101.6 0.0 7.5e-29 99.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG43234.1 - 1.7e-28 98.9 1.2 5.5e-28 97.3 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF3138 PF11336.8 GBG43234.1 - 0.89 8.1 2.0 1.5 7.3 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) rve PF00665.26 GBG43246.1 - 8.4e-16 58.2 0.0 1.4e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain eIF-1a PF01176.19 GBG43246.1 - 0.012 15.5 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Chromo PF00385.24 GBG43246.1 - 0.086 12.8 0.1 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Microvir_J PF04726.13 GBG43248.1 - 0.023 14.6 13.8 3.5 7.7 0.1 4.8 4 1 1 5 5 5 0 Microvirus J protein ABC2_membrane PF01061.24 GBG43253.1 - 4.1e-40 137.5 18.6 4.9e-40 137.2 18.6 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 GBG43253.1 - 0.0014 17.8 21.6 0.0014 17.8 21.6 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein PDR_assoc PF08370.11 GBG43263.1 - 2 8.2 4.2 1 9.1 1.1 1.9 1 1 1 2 2 2 0 Plant PDR ABC transporter associated RVT_1 PF00078.27 GBG43270.1 - 2.8e-28 99.0 0.0 4.1e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG43270.1 - 7e-28 96.6 0.0 1.7e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG43270.1 - 4.3e-26 91.2 0.0 9.6e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG43275.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG43275.1 - 0.0019 18.4 0.2 0.005 17.0 0.1 1.8 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_4 PF13359.6 GBG43311.1 - 2.4e-22 79.3 0.0 3.4e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG43311.1 - 5.1e-15 55.6 0.0 1.3e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG43311.1 - 0.0054 16.4 0.3 4 7.0 0.0 2.5 2 1 0 2 2 2 2 Transposase DDE domain Lipoxygenase PF00305.19 GBG43316.1 - 1.4e-120 403.8 0.0 9.4e-114 381.2 0.0 2.5 1 1 1 2 2 2 2 Lipoxygenase RVT_1 PF00078.27 GBG43317.1 - 7.3e-31 107.4 0.0 1.2e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG43317.1 - 1.8e-23 82.4 0.0 5.7e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG43317.1 - 1.6e-19 70.1 0.0 3.4e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG43317.1 - 6.9e-08 32.3 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG43317.1 - 7.8e-08 32.9 0.0 1.7e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG43317.1 - 5.1e-05 23.8 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG43317.1 - 0.0034 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF4187 PF13821.6 GBG43319.1 - 0.00092 18.9 0.6 0.0023 17.6 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Tox-HNH-EHHH PF15657.6 GBG43319.1 - 0.045 14.1 0.4 2.3 8.6 0.2 2.3 1 1 1 2 2 2 0 HNH/Endo VII superfamily nuclease toxins Lipin_mid PF16876.5 GBG43319.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain CENP-K PF11802.8 GBG43320.1 - 0.027 14.1 3.0 0.053 13.1 3.0 1.5 1 1 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 GBG43320.1 - 0.09 12.8 12.0 0.1 12.6 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CREPT PF16566.5 GBG43320.1 - 2.1 8.5 8.0 11 6.2 0.3 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4407 PF14362.6 GBG43320.1 - 4 6.7 26.0 19 4.5 24.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spt20 PF12090.8 GBG43320.1 - 9.6 5.7 10.8 7.6 6.1 0.3 2.2 2 0 0 2 2 2 0 Spt20 family Methyltransf_32 PF13679.6 GBG43330.1 - 2.3e-07 31.0 0.7 6.4e-07 29.5 0.7 1.8 1 0 0 1 1 1 1 Methyltransferase domain RT_RNaseH_2 PF17919.1 GBG43351.1 - 1.2e-29 102.3 0.0 2.2e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG43351.1 - 1.1e-26 93.2 0.1 2e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG43351.1 - 1.5e-16 60.7 0.0 3.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG43351.1 - 9.7e-14 51.2 0.0 9.7e-14 51.2 0.0 3.0 4 0 0 4 4 4 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG43351.1 - 0.0028 17.8 0.0 0.0086 16.3 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG43351.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 GBG43404.1 - 0.052 12.3 8.8 0.072 11.8 8.8 1.2 1 0 0 1 1 1 0 Presenilin FYDLN_acid PF09538.10 GBG43404.1 - 0.54 11.0 16.3 0.46 11.2 6.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RNA_pol_Rpc4 PF05132.14 GBG43404.1 - 1.1 9.7 7.1 0.8 10.1 0.3 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 GBG43404.1 - 3.9 7.2 21.6 0.7 9.7 9.9 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 GBG43404.1 - 5.2 5.7 7.6 6.9 5.3 7.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM176 PF14851.6 GBG43407.1 - 6.8e-06 25.8 4.5 0.00069 19.3 0.4 2.1 2 0 0 2 2 2 2 FAM176 family BSP_II PF05432.11 GBG43407.1 - 0.00015 21.6 19.7 0.00019 21.3 19.7 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 GBG43407.1 - 0.00041 20.3 5.7 0.02 14.8 1.4 2.1 2 0 0 2 2 2 2 Myc amino-terminal region BUD22 PF09073.10 GBG43407.1 - 0.00067 19.1 7.3 0.00078 18.9 7.3 1.1 1 0 0 1 1 1 1 BUD22 RXT2_N PF08595.11 GBG43407.1 - 0.021 14.8 8.3 0.22 11.5 3.6 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Mpp10 PF04006.12 GBG43407.1 - 0.025 13.1 10.4 0.034 12.6 10.4 1.1 1 0 0 1 1 1 0 Mpp10 protein Plasmodium_Vir PF05795.11 GBG43407.1 - 0.038 13.4 2.0 0.047 13.1 2.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4481 PF14800.6 GBG43407.1 - 0.058 12.9 0.3 0.1 12.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) DNA_pol_phi PF04931.13 GBG43407.1 - 0.066 11.3 13.1 0.086 10.9 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 GBG43407.1 - 0.084 12.9 5.7 0.11 12.5 5.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1770 PF08589.10 GBG43407.1 - 0.092 13.7 2.2 3.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) MDM1 PF15501.6 GBG43407.1 - 0.11 11.6 11.5 0.14 11.3 11.5 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 DUF3899 PF13038.6 GBG43407.1 - 0.14 12.7 3.7 1.7 9.2 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Presenilin PF01080.17 GBG43407.1 - 0.15 10.8 3.2 0.19 10.5 3.2 1.1 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 GBG43407.1 - 0.37 10.7 9.6 0.27 11.1 4.4 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4611 PF15387.6 GBG43407.1 - 0.47 10.7 15.1 0.26 11.5 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TLP-20 PF06088.11 GBG43407.1 - 0.63 9.9 4.2 4.1 7.3 0.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PGA2 PF07543.12 GBG43407.1 - 0.66 10.0 16.0 2.5 8.1 1.1 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF2956 PF11169.8 GBG43407.1 - 0.77 10.0 7.4 1.2 9.4 4.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) AIM3 PF17096.5 GBG43407.1 - 0.97 10.4 7.6 9.6 7.2 0.1 2.5 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 PBP1_TM PF14812.6 GBG43407.1 - 1.5 9.3 13.4 5.4 7.5 0.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AP3D1 PF06375.11 GBG43407.1 - 1.9 8.7 12.3 1.2 9.4 7.0 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 CDV3 PF15359.6 GBG43407.1 - 2.4 8.7 11.0 35 4.9 9.1 2.3 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF4820 PF16091.5 GBG43407.1 - 3.5 6.9 7.8 0.49 9.7 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CENP-B_dimeris PF09026.10 GBG43407.1 - 3.9 7.9 13.7 1.4 9.3 0.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Prothymosin PF03247.14 GBG43407.1 - 5.6 7.5 32.3 1.3 9.5 14.9 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family FYDLN_acid PF09538.10 GBG43407.1 - 6.5 7.5 15.5 15 6.3 15.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GEMIN8 PF15348.6 GBG43407.1 - 7.6 6.8 14.9 0.39 11.0 5.0 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Nucleo_P87 PF07267.11 GBG43407.1 - 8 5.2 8.8 0.27 10.1 1.7 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Asp_protease_2 PF13650.6 GBG43420.1 - 0.00083 20.0 0.1 0.0029 18.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG43420.1 - 0.0036 17.8 0.2 0.015 15.9 0.0 2.1 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG43427.1 - 2.9e-32 110.7 0.0 4.7e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG43427.1 - 4.3e-27 94.4 0.0 7.4e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG43427.1 - 1.6e-19 69.7 0.1 3.3e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG43427.1 - 0.00018 21.6 0.0 0.0007 19.8 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG43427.1 - 0.17 11.4 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cwf_Cwc_15 PF04889.12 GBG43439.1 - 0.13 12.0 21.3 0.22 11.2 21.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG43439.1 - 0.29 10.5 20.0 0.47 9.8 20.0 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG43439.1 - 0.59 8.3 19.5 0.75 7.9 19.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG43439.1 - 1.6 7.9 20.9 2.5 7.3 20.9 1.2 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 GBG43439.1 - 1.9 8.0 15.0 2.8 7.4 15.0 1.3 1 0 0 1 1 1 0 PPP4R2 FYDLN_acid PF09538.10 GBG43457.1 - 0.013 16.2 3.7 0.015 15.9 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4611 PF15387.6 GBG43457.1 - 0.14 12.4 6.8 0.17 12.1 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SGT1 PF07093.11 GBG43457.1 - 0.2 10.1 4.2 0.23 9.9 4.2 1.1 1 0 0 1 1 1 0 SGT1 protein NOA36 PF06524.12 GBG43457.1 - 0.25 10.6 5.2 0.25 10.6 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GBG43457.1 - 0.59 9.8 6.3 0.72 9.5 6.3 1.2 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 GBG43457.1 - 0.59 10.5 6.7 0.77 10.2 6.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PA26 PF04636.13 GBG43457.1 - 0.69 8.8 3.2 0.72 8.7 3.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Utp14 PF04615.13 GBG43457.1 - 0.78 8.2 10.8 0.88 8.1 10.8 1.0 1 0 0 1 1 1 0 Utp14 protein Paf1 PF03985.13 GBG43457.1 - 0.79 8.7 9.0 0.9 8.5 9.0 1.0 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 GBG43457.1 - 0.96 7.7 6.9 1 7.6 6.9 1.0 1 0 0 1 1 1 0 CDC45-like protein GCIP PF13324.6 GBG43457.1 - 1 8.9 6.9 1.1 8.8 6.9 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PBP_sp32 PF07222.12 GBG43457.1 - 3.7 6.9 6.8 4.1 6.8 6.8 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CENP-B_dimeris PF09026.10 GBG43457.1 - 4.8 7.6 11.3 6.3 7.2 11.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 GBG43457.1 - 5 5.1 10.2 5.3 5.0 10.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi ABC_tran PF00005.27 GBG43471.1 - 1.4e-09 38.6 0.0 1.4e-09 38.6 0.0 1.0 1 0 0 1 1 1 1 ABC transporter Myb_DNA-bind_4 PF13837.6 GBG43494.1 - 1e-07 32.3 2.0 2.2e-07 31.1 2.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain GRIM-19 PF06212.12 GBG43501.1 - 6.3 6.8 11.1 0.093 12.7 2.4 2.2 2 1 1 3 3 3 0 GRIM-19 protein zf-CCHC PF00098.23 GBG43509.1 - 1.7e-05 24.7 0.8 2.9e-05 24.0 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG43509.1 - 0.18 11.7 1.7 0.53 10.1 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle BORG_CEP PF14957.6 GBG43529.1 - 1.5 10.0 10.8 1.8 9.7 10.8 1.3 1 0 0 1 1 1 0 Cdc42 effector CDC27 PF09507.10 GBG43529.1 - 1.7 7.9 29.1 1.8 7.9 29.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Membralin PF09746.9 GBG43529.1 - 2.1 7.3 3.4 2 7.4 3.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 GBG43529.1 - 3.6 6.2 20.9 3.5 6.3 20.9 1.1 1 0 0 1 1 1 0 Presenilin Nucleo_P87 PF07267.11 GBG43529.1 - 3.9 6.2 9.5 4.6 6.0 9.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MDM10 PF12519.8 GBG43529.1 - 4.4 6.1 12.2 4.5 6.0 12.2 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF5427 PF10310.9 GBG43529.1 - 4.5 6.1 21.4 4.8 6.0 21.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Peptidase_S64 PF08192.11 GBG43529.1 - 7.6 4.9 9.4 7.4 4.9 9.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.7 GBG43529.1 - 7.9 4.5 13.2 7 4.6 13.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 GBG43529.1 - 9 5.2 16.5 11 5.0 16.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Ripply PF14998.6 GBG43535.1 - 1.4 9.6 7.7 37 5.0 0.0 3.1 3 1 0 3 3 3 0 Transcription Regulator Presenilin PF01080.17 GBG43535.1 - 7.5 5.2 6.2 11 4.7 6.2 1.1 1 0 0 1 1 1 0 Presenilin MAP7 PF05672.11 GBG43551.1 - 0.0039 16.9 21.2 0.0039 16.9 21.2 2.1 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family DUF1664 PF07889.12 GBG43551.1 - 0.012 15.7 2.1 0.012 15.7 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 GBG43551.1 - 0.069 12.0 6.6 0.087 11.7 6.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Pinin_SDK_memA PF04696.13 GBG43551.1 - 6.5 6.8 37.6 3.3 7.8 18.6 2.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF4192 PF13830.6 GBG43551.1 - 7.9 6.4 15.0 0.22 11.5 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) rve PF00665.26 GBG43555.1 - 4.4e-20 72.0 0.0 8.8e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG43555.1 - 0.02 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Ribosomal_60s PF00428.19 GBG43557.1 - 0.075 13.6 8.4 0.075 13.6 8.4 3.1 2 1 1 3 3 3 0 60s Acidic ribosomal protein AP3D1 PF06375.11 GBG43557.1 - 5.7 7.2 13.7 6.4 7.0 2.0 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 RT_RNaseH PF17917.1 GBG43564.1 - 1.1e-20 73.9 0.0 1.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG43564.1 - 4.6e-18 65.1 0.0 7.4e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG43564.1 - 3e-14 52.9 0.1 7.1e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG43564.1 - 6.5e-06 26.3 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG43564.1 - 0.029 14.6 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG43630.1 - 1.2e-19 70.5 0.0 6.1e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG43630.1 - 6.6e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG43630.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 1 1 0 1 1 1 0 Transposase DDE domain Presenilin PF01080.17 GBG43637.1 - 0.092 11.5 7.2 0.13 11.0 7.2 1.2 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 GBG43637.1 - 6.1 6.1 25.3 7.6 5.8 25.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Retrotrans_gag PF03732.17 GBG43645.1 - 0.008 16.4 0.1 0.008 16.4 0.1 3.1 3 1 1 4 4 4 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG43655.1 - 9.7e-06 25.4 1.8 9.7e-06 25.4 1.8 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG43655.1 - 0.0065 16.3 0.5 0.015 15.1 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle PGA_cap PF09587.10 GBG43655.1 - 0.24 10.8 1.6 0.38 10.2 1.6 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap RR_TM4-6 PF06459.12 GBG43655.1 - 1.6 8.5 11.1 0.34 10.7 7.9 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 XRN_M PF17846.1 GBG43655.1 - 2.7 6.8 9.3 3.9 6.3 9.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF1013 PF06242.11 GBG43655.1 - 4.8 7.2 9.4 2.6 8.1 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) Tho2 PF11262.8 GBG43655.1 - 4.9 6.3 7.6 8.9 5.4 7.6 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3138 PF11336.8 GBG43690.1 - 0.59 8.7 3.4 1 7.9 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) REV PF00424.18 GBG43690.1 - 6.6 6.8 7.4 1.7 8.7 0.7 2.9 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) RT_RNaseH PF17917.1 GBG43702.1 - 2.3e-20 72.8 0.2 4.9e-20 71.8 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG43702.1 - 1.6e-12 47.3 0.0 3.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DegQ PF08181.11 GBG43702.1 - 6.7 6.9 5.9 32 4.7 0.1 2.6 2 0 0 2 2 2 0 DegQ (SacQ) family RT_RNaseH_2 PF17919.1 GBG43713.1 - 1.9e-32 111.3 0.0 4e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG43713.1 - 9.7e-30 103.0 0.0 1.9e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG43713.1 - 3.3e-29 102.0 0.0 5.4e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG43713.1 - 2.4e-14 53.2 0.3 4.6e-14 52.3 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG43713.1 - 4.7e-11 42.9 0.5 9.1e-10 38.8 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.27 GBG43732.1 - 3.4e-31 108.5 0.0 5.2e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG43732.1 - 1.9e-08 34.2 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG43732.1 - 4.4e-08 33.7 0.0 1e-07 32.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG43732.1 - 8.6e-06 26.2 0.0 2.2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG43732.1 - 0.00065 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG43732.1 - 0.081 12.0 0.1 0.23 10.5 0.1 1.6 1 1 0 1 1 1 0 Autophagy protein Apg17 Asp_protease_2 PF13650.6 GBG43743.1 - 0.061 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG43743.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 GBG43745.1 - 2.8 6.6 17.2 3.7 6.2 17.2 1.1 1 0 0 1 1 1 0 Presenilin Prothymosin PF03247.14 GBG43745.1 - 4.7 7.7 62.7 3.3 8.2 12.9 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family SAPS PF04499.15 GBG43745.1 - 9 4.9 15.6 11 4.7 15.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RVT_1 PF00078.27 GBG43817.1 - 9.6e-20 71.0 0.2 1.6e-19 70.3 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG43817.1 - 3.7e-16 59.0 1.3 1.3e-15 57.2 0.1 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG43817.1 - 1.4e-12 47.9 0.0 3.5e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG43817.1 - 7.7e-11 41.7 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG43817.1 - 3.8e-06 27.0 0.0 9.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Nop14 PF04147.12 GBG43861.1 - 0.018 13.3 29.9 0.023 13.0 29.9 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG43861.1 - 2.2 6.8 27.8 2.5 6.6 27.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Prok-TraM PF09228.10 GBG43864.1 - 2 8.8 5.6 6.3 7.2 0.8 2.1 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM Beta_helix PF13229.6 GBG43896.1 - 1e-07 32.0 1.5 4.3e-05 23.4 0.3 2.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 GBG43896.1 - 0.081 12.2 0.0 0.16 11.2 0.0 1.5 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 GBG43896.1 - 0.14 12.7 30.5 0.53 10.9 0.9 6.2 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Flagellin_IN PF07196.13 GBG43896.1 - 0.75 10.0 4.6 0.73 10.1 2.4 2.2 2 0 0 2 2 2 0 Flagellin hook IN motif DctP PF03480.13 GBG43910.1 - 5.9e-13 48.8 0.0 9.5e-13 48.1 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 CDC45 PF02724.14 GBG43922.1 - 0.00056 18.3 10.2 0.00062 18.2 10.2 1.0 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GBG43922.1 - 0.0047 16.4 16.9 0.0057 16.1 16.9 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG43922.1 - 0.0048 15.2 16.1 0.0056 15.0 16.1 1.0 1 0 0 1 1 1 1 Nop14-like family Sporozoite_P67 PF05642.11 GBG43922.1 - 0.01 14.0 5.4 0.012 13.8 5.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2052 PF09747.9 GBG43922.1 - 0.057 13.5 14.2 0.077 13.1 14.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNA_polI_A34 PF08208.11 GBG43922.1 - 0.19 11.8 8.6 0.25 11.4 8.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Zip PF02535.22 GBG43922.1 - 0.63 9.2 2.8 0.67 9.1 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter LAP1C PF05609.12 GBG43922.1 - 0.74 8.8 7.5 0.85 8.6 7.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 GBG43922.1 - 1 8.0 5.1 1.2 7.8 5.1 1.1 1 0 0 1 1 1 0 Presenilin DARPP-32 PF05395.12 GBG43922.1 - 1.1 9.5 13.8 1.7 8.8 13.8 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 TCP PF03634.13 GBG43922.1 - 1.7 9.2 9.4 2.5 8.6 9.4 1.2 1 0 0 1 1 1 0 TCP family transcription factor BSP_II PF05432.11 GBG43922.1 - 1.8 8.2 27.8 3 7.4 27.8 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Mpp10 PF04006.12 GBG43922.1 - 2.4 6.5 21.9 3.1 6.1 21.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop53 PF07767.11 GBG43922.1 - 3.3 7.0 20.5 4.3 6.6 20.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNA_pol_Rpc4 PF05132.14 GBG43922.1 - 4.4 7.7 6.7 6.7 7.1 6.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 GBG43922.1 - 4.9 6.9 14.3 6.7 6.5 14.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 GBG43922.1 - 5.2 6.8 5.7 6.9 6.4 5.7 1.1 1 0 0 1 1 1 0 Connexin eIF-3c_N PF05470.12 GBG43922.1 - 5.6 5.1 7.5 6.3 5.0 7.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Cytomega_UL84 PF06284.11 GBG43922.1 - 8.1 4.8 14.1 9.8 4.5 14.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein zf-CCHC PF00098.23 GBG43959.1 - 8.2e-07 28.8 1.3 8.2e-07 28.8 1.3 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG43959.1 - 0.0037 17.1 1.3 0.0077 16.0 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG43959.1 - 0.06 13.1 0.4 0.16 11.7 0.4 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger ERM PF00769.19 GBG43959.1 - 0.28 11.0 35.2 0.02 14.7 17.6 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CorA PF01544.18 GBG43959.1 - 0.52 9.6 4.6 1.9 7.7 4.6 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein RMI1_N PF08585.12 GBG43979.1 - 0.27 10.9 5.4 0.66 9.7 5.4 1.6 1 0 0 1 1 1 0 RecQ mediated genome instability protein Presenilin PF01080.17 GBG43979.1 - 2.1 7.0 2.9 2.9 6.6 2.9 1.3 1 0 0 1 1 1 0 Presenilin Gpr1_Fun34_YaaH PF01184.19 GBG44016.1 - 2.2e-39 135.2 22.2 2.8e-39 134.9 22.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 GBG44016.1 - 0.055 13.9 14.4 0.31 11.5 0.4 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 GBG44016.1 - 0.77 9.4 8.6 0.75 9.5 7.4 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF1287 PF06940.11 GBG44032.1 - 0.039 13.6 0.1 0.039 13.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1287) Isy1 PF06246.12 GBG44035.1 - 3.4e-91 305.3 15.1 5.1e-91 304.8 15.1 1.3 1 0 0 1 1 1 1 Isy1-like splicing family Troponin PF00992.20 GBG44035.1 - 0.0023 18.3 0.9 0.0023 18.3 0.9 3.3 4 0 0 4 4 4 1 Troponin CENP-B_dimeris PF09026.10 GBG44035.1 - 0.0084 16.5 6.2 0.017 15.5 6.2 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain TMEM119 PF15724.5 GBG44035.1 - 0.22 11.6 5.0 0.35 10.9 5.0 1.3 1 0 0 1 1 1 0 TMEM119 family ANAPC15 PF15243.6 GBG44035.1 - 0.5 10.8 12.7 1.7 9.1 12.7 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DNA_pol_phi PF04931.13 GBG44035.1 - 0.61 8.1 9.3 0.9 7.6 9.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG44035.1 - 0.62 8.3 10.7 0.93 7.7 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 GBG44035.1 - 1.5 8.6 5.1 2.6 7.8 5.1 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 GBG44035.1 - 1.6 8.0 11.6 2.4 7.4 11.6 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 GBG44035.1 - 2.4 8.4 18.3 0.11 12.8 12.1 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CPSF100_C PF13299.6 GBG44035.1 - 2.4 8.3 6.8 0.36 11.0 2.7 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal NOA36 PF06524.12 GBG44057.1 - 0.61 9.4 14.0 0.58 9.4 14.0 1.0 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GBG44057.1 - 1 9.8 17.6 1.2 9.6 17.6 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 GBG44057.1 - 2.7 7.6 7.5 3.5 7.3 7.5 1.3 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.13 GBG44057.1 - 3 6.7 10.7 2.7 6.9 10.7 1.0 1 0 0 1 1 1 0 Paf1 RXT2_N PF08595.11 GBG44057.1 - 3.5 7.6 8.2 3.3 7.7 8.2 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4637 PF15470.6 GBG44057.1 - 4.7 6.9 11.9 5 6.8 11.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CobT PF06213.12 GBG44057.1 - 7.4 5.9 13.2 7.2 5.9 13.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NAD_binding_10 PF13460.6 GBG44104.1 - 3.7e-21 75.8 0.0 1.1e-20 74.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 GBG44104.1 - 4.8e-12 45.9 0.0 1.1e-11 44.7 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GBG44104.1 - 4.1e-10 39.5 0.0 8.1e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GBG44104.1 - 8.3e-06 25.0 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GBG44104.1 - 9.4e-05 22.0 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 GBG44104.1 - 0.0015 19.0 0.1 0.0035 17.8 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 GBG44104.1 - 0.0017 17.5 0.0 0.0048 16.1 0.0 1.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 GBG44104.1 - 0.0018 17.8 0.1 0.003 17.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 GBG44104.1 - 0.0038 16.4 0.1 0.0091 15.1 0.1 1.6 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 GBG44104.1 - 0.031 14.2 0.2 0.1 12.5 0.2 1.9 1 0 0 1 1 1 0 KR domain OCRE PF17780.1 GBG44104.1 - 0.039 14.0 0.4 0.065 13.3 0.4 1.3 1 0 0 1 1 1 0 OCRE domain NAD_binding_4 PF07993.12 GBG44104.1 - 0.043 13.0 0.1 0.13 11.4 0.1 1.8 2 0 0 2 2 2 0 Male sterility protein DapB_N PF01113.20 GBG44104.1 - 0.15 12.2 0.4 0.27 11.3 0.4 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus tRNA-synt_1 PF00133.22 GBG44159.1 - 4.3e-24 84.7 0.0 4.4e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GBG44159.1 - 0.00012 21.0 0.0 0.00012 21.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GBG44159.1 - 0.00036 20.0 0.0 0.00038 19.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 GBG44159.1 - 0.0007 18.6 0.0 0.00079 18.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (K) Chromo PF00385.24 GBG44162.1 - 5.9e-12 45.3 0.0 9.5e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG44184.1 - 4.3e-27 94.1 0.0 7.6e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG44184.1 - 8e-26 90.4 0.0 1.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG44184.1 - 1.4e-18 66.7 0.3 3.7e-18 65.4 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain BKACE PF05853.12 GBG44238.1 - 2.8e-79 266.3 0.1 6.9e-79 265.0 0.1 1.6 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme adh_short_C2 PF13561.6 GBG44238.1 - 6.5e-46 156.8 2.5 1.3e-45 155.7 2.5 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GBG44238.1 - 3.3e-35 121.3 0.0 6.7e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Dioxygenase_C PF00775.21 GBG44238.1 - 4.7e-15 55.5 0.0 8.4e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase ABC_tran PF00005.27 GBG44238.1 - 4.9e-15 56.2 0.0 1.1e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter KR PF08659.10 GBG44238.1 - 4.4e-06 26.7 0.1 9.3e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 KR domain SMC_N PF02463.19 GBG44238.1 - 0.032 13.6 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain N_formyltrans_C PF18216.1 GBG44238.1 - 0.036 13.8 0.2 3.7 7.3 0.0 3.7 4 0 0 4 4 4 0 N-formyltransferase dimerization C-terminal domain AAA_21 PF13304.6 GBG44238.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 GBG44238.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Retrotrans_gag PF03732.17 GBG44243.1 - 0.00085 19.5 10.6 0.0012 19.0 0.1 4.3 4 1 0 4 4 4 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG44243.1 - 0.026 15.1 3.6 0.026 15.1 3.6 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SPARC_Ca_bdg PF10591.9 GBG44243.1 - 0.24 11.7 1.8 0.75 10.1 1.8 2.0 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4407 PF14362.6 GBG44243.1 - 1.7 7.9 16.8 0.9 8.8 7.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 GBG44243.1 - 8.7 6.7 9.5 3.3 8.1 1.2 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-CCHC PF00098.23 GBG44244.1 - 0.0069 16.4 0.4 0.014 15.5 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG44244.1 - 0.17 11.6 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle GMC_oxred_C PF05199.13 GBG44244.1 - 6.3 7.3 5.9 2.3 8.8 0.2 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Dimer_Tnp_hAT PF05699.14 GBG44306.1 - 1.6e-06 27.8 0.1 1.6e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Ribosomal_60s PF00428.19 GBG44306.1 - 0.2 12.3 19.1 0.21 12.2 8.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein LAP1C PF05609.12 GBG44306.1 - 1.8 7.5 28.7 2.4 7.2 28.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TonB_dep_Rec PF00593.24 GBG44311.1 - 2.7e-46 159.4 16.2 2.9e-46 159.3 16.2 1.0 1 0 0 1 1 1 1 TonB dependent receptor Integrase_H2C2 PF17921.1 GBG44321.1 - 2.8e-16 59.4 2.1 4.3e-16 58.8 0.6 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG44321.1 - 3.8e-09 36.8 0.0 7.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG44321.1 - 0.0025 18.0 0.1 0.0059 16.8 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG44351.1 - 0.00012 22.2 1.6 0.00044 20.5 0.1 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein FAT PF02259.23 GBG44351.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 FAT domain SNAPc19 PF15497.6 GBG44351.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 NPR3 PF03666.13 GBG44372.1 - 0.35 9.6 12.7 0.3 9.8 12.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 GBG44372.1 - 0.57 10.4 12.5 0.62 10.2 12.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NOA36 PF06524.12 GBG44372.1 - 0.59 9.4 16.8 0.64 9.3 16.8 1.2 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 GBG44372.1 - 0.59 8.8 10.7 0.51 9.0 10.7 1.0 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 GBG44372.1 - 0.6 9.0 8.1 0.53 9.2 8.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_polI_A34 PF08208.11 GBG44372.1 - 0.82 9.7 32.2 1.2 9.2 32.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PPP4R2 PF09184.11 GBG44372.1 - 1.2 8.7 20.7 1.1 8.8 20.7 1.1 1 0 0 1 1 1 0 PPP4R2 DDHD PF02862.17 GBG44372.1 - 2.6 8.1 6.2 2.5 8.2 6.2 1.1 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.12 GBG44372.1 - 4.3 5.4 30.4 4.4 5.4 30.4 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG44372.1 - 8.3 6.1 23.4 9.8 5.9 23.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 rve PF00665.26 GBG44377.1 - 6.3e-07 29.6 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG44377.1 - 0.046 13.4 0.1 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Clr5 PF14420.6 GBG44377.1 - 0.36 11.1 2.1 7.4 6.9 0.7 2.8 3 0 0 3 3 3 0 Clr5 domain NOG1_N PF17835.1 GBG44384.1 - 2.2e-54 183.8 0.5 5.2e-54 182.5 0.5 1.7 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 GBG44384.1 - 2.3e-28 97.9 1.0 8.4e-28 96.1 1.0 2.1 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 GBG44384.1 - 1.5e-25 88.7 0.9 3.5e-25 87.5 0.0 2.1 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 GBG44384.1 - 1.9e-18 66.6 0.0 4.1e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG44384.1 - 1.8e-09 37.3 0.0 3.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 GBG44384.1 - 0.00028 20.4 0.0 0.00059 19.3 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 GBG44384.1 - 0.00042 20.4 0.9 0.6 10.2 0.0 3.2 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 GBG44384.1 - 0.0029 17.0 0.0 0.0069 15.7 0.0 1.6 1 0 0 1 1 1 1 AIG1 family DDE_Tnp_ISL3 PF01610.17 GBG44384.1 - 0.017 14.8 2.0 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Transposase AAA_16 PF13191.6 GBG44384.1 - 0.099 13.0 0.6 0.68 10.3 0.0 2.7 4 0 0 4 4 4 0 AAA ATPase domain Roc PF08477.13 GBG44384.1 - 0.12 12.6 0.0 1.1 9.6 0.0 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GBG44384.1 - 0.12 12.2 0.0 0.94 9.4 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 GBG44384.1 - 0.13 12.8 0.4 1.6 9.3 0.0 3.0 3 1 1 4 4 4 0 AAA domain RNA_pol_Rpb2_6 PF00562.28 GBG44402.1 - 2.3e-124 415.4 0.2 3.1e-124 415.0 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 HlyD_D23 PF16576.5 GBG44402.1 - 0.062 12.5 0.8 2 7.6 0.2 2.6 3 0 0 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion EIF_2_alpha PF07541.12 GBG44402.1 - 0.15 12.2 0.4 2 8.5 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit Spc7 PF08317.11 GBG44402.1 - 0.38 9.6 6.2 0.7 8.7 6.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 GBG44402.1 - 0.76 10.2 3.7 1.5 9.3 0.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3138 PF11336.8 GBG44416.1 - 0.55 8.8 3.6 1 7.9 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Retrotrans_gag PF03732.17 GBG44443.1 - 0.0041 17.4 0.1 0.034 14.4 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein YusW PF14039.6 GBG44443.1 - 0.012 16.1 0.3 0.088 13.3 0.1 2.5 3 0 0 3 3 3 0 YusW-like protein TolA_bind_tri PF16331.5 GBG44443.1 - 0.018 15.1 1.8 0.018 15.1 1.8 2.4 3 0 0 3 3 3 0 TolA binding protein trimerisation CBM-like PF14683.6 GBG44462.1 - 1.8e-31 109.2 0.0 2.3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 GBG44462.1 - 1.4e-14 53.6 0.6 2.4e-14 52.9 0.6 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 GBG44462.1 - 0.0013 18.9 0.1 0.0033 17.7 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Y_Y_Y PF07495.13 GBG44462.1 - 0.036 14.0 0.5 0.13 12.2 0.0 2.2 3 0 0 3 3 3 0 Y_Y_Y domain zf-C3HC4_3 PF13920.6 GBG44466.1 - 0.073 12.9 11.1 0.13 12.1 11.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG44466.1 - 0.15 12.5 13.2 0.27 11.6 13.2 1.5 1 0 0 1 1 1 0 Ring finger domain DUF3563 PF12086.8 GBG44469.1 - 0.2 11.4 1.0 0.57 10.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) rve PF00665.26 GBG44492.1 - 1.6e-15 57.3 0.1 2.9e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG44492.1 - 0.034 13.8 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Clr5 PF14420.6 GBG44492.1 - 0.26 11.5 2.2 1.3 9.4 0.4 2.7 3 0 0 3 3 3 0 Clr5 domain RT_RNaseH_2 PF17919.1 GBG44518.1 - 6.7e-27 93.5 0.0 1.2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG44518.1 - 7.1e-26 90.5 0.0 1.9e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG44518.1 - 0.00038 20.0 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG44518.1 - 0.003 16.8 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 zf-CCHC_5 PF14787.6 GBG44531.1 - 0.019 14.6 0.3 0.049 13.3 0.3 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Angiomotin_C PF12240.8 GBG44531.1 - 0.063 12.8 0.1 0.063 12.8 0.1 2.0 2 0 0 2 2 2 0 Angiomotin C terminal RT_RNaseH_2 PF17919.1 GBG44591.1 - 3.5e-22 78.3 0.0 6.2e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG44591.1 - 4e-22 78.5 0.0 6.5e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG44591.1 - 8.8e-20 70.6 0.5 2.1e-19 69.4 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain ATG16 PF08614.11 GBG44597.1 - 0.18 12.0 1.4 0.24 11.6 1.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Peptidase_C14 PF00656.22 GBG44647.1 - 3.4e-08 33.7 0.0 4.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain rve PF00665.26 GBG44657.1 - 2.1e-09 37.6 0.0 3.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG44657.1 - 0.019 14.8 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Trypsin PF00089.26 GBG44660.1 - 1.5e-29 103.4 0.1 1.6e-29 103.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin MRP-L47 PF06984.13 GBG44667.1 - 0.12 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4360 PF14273.6 GBG44674.1 - 1.4e-51 174.9 0.0 1.6e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) adh_short_C2 PF13561.6 GBG44689.1 - 1.2e-37 129.8 0.1 3.6e-37 128.2 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GBG44689.1 - 9.9e-37 126.3 0.1 1.3e-36 125.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GBG44689.1 - 1.6e-08 34.7 0.1 6.8e-08 32.6 0.0 1.7 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GBG44689.1 - 0.052 12.7 0.1 0.19 10.8 0.1 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 GBG44689.1 - 0.067 13.2 0.7 1.2 9.2 0.3 2.7 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Epimerase PF01370.21 GBG44689.1 - 0.12 11.8 0.2 0.2 11.1 0.2 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family EspB PF05802.11 GBG44689.1 - 0.22 11.5 1.2 0.49 10.4 1.2 1.5 1 0 0 1 1 1 0 Enterobacterial EspB protein EphA2_TM PF14575.6 GBG44703.1 - 0.015 16.1 0.5 0.025 15.5 0.5 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4307 PF14155.6 GBG44703.1 - 0.036 13.9 0.5 0.053 13.3 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Rax2 PF12768.7 GBG44703.1 - 0.043 13.3 0.1 0.046 13.2 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4381 PF14316.6 GBG44703.1 - 0.05 13.8 0.0 0.057 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) GRA6 PF05084.13 GBG44703.1 - 0.064 13.2 0.3 0.1 12.5 0.2 1.4 1 1 0 1 1 1 0 Granule antigen protein (GRA6) TraL PF07178.11 GBG44703.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 TraL protein DAG1 PF05454.11 GBG44703.1 - 0.17 11.3 0.1 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Retrotrans_gag PF03732.17 GBG44717.1 - 0.00041 20.6 6.7 0.00074 19.7 0.1 3.3 2 1 0 2 2 2 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG44717.1 - 0.0096 16.5 3.2 0.0096 16.5 3.2 3.5 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Inhibitor_I29 PF08246.12 GBG44717.1 - 0.067 13.6 0.4 0.2 12.1 0.4 1.8 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) SPARC_Ca_bdg PF10591.9 GBG44717.1 - 0.1 13.0 3.1 0.18 12.1 0.7 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Fzo_mitofusin PF04799.13 GBG44717.1 - 3.2 7.3 6.3 17 5.0 1.7 2.4 2 0 0 2 2 2 0 fzo-like conserved region SUIM_assoc PF16619.5 GBG44717.1 - 8.9 6.5 8.3 2.7 8.1 0.2 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Fasciclin PF02469.22 GBG44729.1 - 1.7e-17 63.9 0.0 2.2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain FAD_syn PF06574.12 GBG44729.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD synthetase PQQ_2 PF13360.6 GBG44754.1 - 2.2e-15 56.9 0.3 3.5e-08 33.3 0.1 2.4 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 GBG44754.1 - 1.4e-14 53.2 2.0 0.0086 16.0 0.5 4.4 4 0 0 4 4 4 4 PQQ enzyme repeat PQQ_3 PF13570.6 GBG44754.1 - 2.7e-11 43.6 17.5 6.7e-05 23.2 0.9 6.8 6 1 0 6 6 6 4 PQQ-like domain zf-CCHC_5 PF14787.6 GBG44804.1 - 0.0017 18.0 2.2 0.0048 16.6 2.2 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 GBG44804.1 - 0.015 15.7 1.2 0.015 15.7 1.2 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Chromo PF00385.24 GBG44807.1 - 0.0012 18.8 0.1 0.0018 18.1 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG44807.1 - 0.01 16.0 0.1 0.025 14.8 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain zf-CCHC PF00098.23 GBG44814.1 - 8.4e-07 28.8 0.8 8.4e-07 28.8 0.8 3.1 4 0 0 4 4 4 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG44814.1 - 0.00022 20.8 0.8 0.00022 20.8 0.8 2.0 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger DUF572 PF04502.13 GBG44814.1 - 0.04 13.5 19.8 0.054 13.1 19.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-CCHC_2 PF13696.6 GBG44814.1 - 0.058 13.2 0.5 0.058 13.2 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG44843.1 - 0.0013 19.0 7.8 0.0057 16.9 0.0 3.7 3 1 0 3 3 3 1 Retrotransposon gag protein SPACA9 PF15120.6 GBG44843.1 - 0.0039 17.0 2.3 0.0071 16.1 1.2 2.0 2 0 0 2 2 2 1 Sperm acrosome-associated protein 9 DUF1664 PF07889.12 GBG44843.1 - 0.26 11.4 4.7 2.1 8.4 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) AIF-MLS PF14962.6 GBG44843.1 - 0.36 10.8 3.6 0.75 9.7 3.6 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence CCDC92 PF14916.6 GBG44843.1 - 1.4 8.8 9.5 7.9 6.3 0.0 3.3 3 0 0 3 3 3 0 Coiled-coil domain of unknown function BLOC1_2 PF10046.9 GBG44843.1 - 2.8 8.3 10.4 0.22 11.8 1.7 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 GBG44843.1 - 4 6.7 16.8 3.2 7.0 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Histone_HNS PF00816.21 GBG44843.1 - 5.8 7.8 11.4 19 6.2 5.9 3.0 3 0 0 3 3 3 0 H-NS histone family FUSC PF04632.12 GBG44843.1 - 6.3 5.2 18.7 0.042 12.4 4.5 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 GBG44843.1 - 7.8 7.0 9.3 2.1 8.8 0.4 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Integrase_H2C2 PF17921.1 GBG44859.1 - 1.7e-30 104.9 0.2 1.7e-13 50.4 0.0 3.5 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG44859.1 - 3.3e-30 105.3 0.0 5.1e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG44859.1 - 5.5e-27 93.4 0.1 4.6e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG44859.1 - 4.1e-25 88.3 0.1 6.4e-11 42.5 0.0 3.0 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG44859.1 - 1.7e-18 66.5 0.0 1.3e-13 50.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG44859.1 - 2.4e-08 34.1 0.2 0.013 15.7 0.0 2.7 2 0 0 2 2 2 2 H2C2 zinc finger RT_RNaseH PF17917.1 GBG44859.1 - 7.4e-08 32.6 0.0 1.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mtf2_C PF14061.6 GBG44859.1 - 0.0072 16.5 0.0 7 6.9 0.0 2.6 2 0 0 2 2 2 2 Polycomb-like MTF2 factor 2 zf-C6H2 PF15801.5 GBG44859.1 - 0.089 13.1 0.5 24 5.4 0.1 2.4 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding SOUL PF04832.12 GBG44860.1 - 7.1e-12 45.8 0.0 8.4e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein RVP_2 PF08284.11 GBG44875.1 - 6.7e-07 29.2 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG44875.1 - 1.9e-06 28.4 0.1 8.3e-06 26.4 0.0 2.1 3 0 0 3 3 3 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG44875.1 - 0.00011 22.4 0.1 0.00023 21.4 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG44875.1 - 0.00086 19.8 0.0 0.0019 18.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG44875.1 - 0.0032 17.3 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG44875.1 - 0.021 14.4 0.5 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG44965.1 - 1.2e-05 25.4 0.2 2.9e-05 24.2 0.2 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein Peptidase_S64 PF08192.11 GBG44973.1 - 0.021 13.4 1.6 0.031 12.8 1.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 Retrotrans_gag PF03732.17 GBG44973.1 - 0.047 14.0 1.7 0.29 11.4 0.0 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein MCU PF04678.13 GBG44973.1 - 0.34 11.0 4.7 0.26 11.4 1.6 2.2 2 1 0 2 2 2 0 Mitochondrial calcium uniporter SDA1 PF05285.12 GBG44990.1 - 0.027 13.9 21.0 0.037 13.5 21.0 1.1 1 0 0 1 1 1 0 SDA1 DUF4366 PF14283.6 GBG44990.1 - 0.31 11.1 2.8 0.55 10.3 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 GBG44990.1 - 2.8 6.6 13.4 3.7 6.2 13.4 1.0 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 GBG44990.1 - 2.9 8.3 5.4 4.7 7.6 5.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 GBG44990.1 - 6.1 5.5 6.7 7.8 5.2 6.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PS_Dcarbxylase PF02666.15 GBG45014.1 - 1.9e-10 40.6 0.7 2e-10 40.6 0.7 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Glyco_hydro_1 PF00232.18 GBG45034.1 - 4.4e-160 533.0 0.0 5.3e-160 532.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 RVT_1 PF00078.27 GBG45101.1 - 1.7e-35 122.6 0.0 2.8e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG45101.1 - 1.7e-31 108.2 0.0 6.6e-31 106.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG45101.1 - 5.5e-30 103.8 0.1 1.3e-29 102.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase THB PF18362.1 GBG45250.1 - 0.0041 16.7 0.0 0.0087 15.6 0.0 1.6 1 0 0 1 1 1 1 Tri-helix bundle domain XhlA PF10779.9 GBG45260.1 - 5.9 7.2 8.0 0.31 11.3 0.9 2.5 3 0 0 3 3 3 0 Haemolysin XhlA XhlA PF10779.9 GBG45266.1 - 5.9 7.2 8.0 0.31 11.3 0.9 2.5 3 0 0 3 3 3 0 Haemolysin XhlA CDC45 PF02724.14 GBG45287.1 - 3.2 5.9 6.5 2.8 6.1 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG45308.1 - 0.22 10.8 9.5 0.22 10.8 9.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 GBG45308.1 - 0.4 9.8 11.4 0.35 9.9 11.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GBG45308.1 - 0.49 8.4 7.1 0.48 8.5 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 GBG45308.1 - 1 9.0 9.6 1 9.1 9.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 GBG45308.1 - 1.2 9.6 14.2 1.6 9.2 14.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YL1 PF05764.13 GBG45308.1 - 2.2 8.3 7.5 2.4 8.2 7.5 1.0 1 0 0 1 1 1 0 YL1 nuclear protein CPSF100_C PF13299.6 GBG45351.1 - 0.32 11.2 11.0 0.35 11.0 4.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FAM76 PF16046.5 GBG45351.1 - 0.42 9.9 16.7 0.85 8.9 15.8 1.7 1 1 1 2 2 2 0 FAM76 protein FAM176 PF14851.6 GBG45351.1 - 0.45 10.2 15.0 0.61 9.7 6.6 2.5 2 0 0 2 2 2 0 FAM176 family RNA_polI_A34 PF08208.11 GBG45351.1 - 1.3 9.1 19.4 0.34 11.0 8.9 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4746 PF15928.5 GBG45351.1 - 1.6 8.1 14.8 0.42 10.0 6.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RAB3GAP2_C PF14656.6 GBG45351.1 - 1.9 6.6 6.5 1.3 7.2 5.1 1.3 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RPA43_OB PF17875.1 GBG45351.1 - 3.2 8.4 12.2 12 6.5 3.7 2.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Vfa1 PF08432.10 GBG45351.1 - 4.1 7.7 15.7 4 7.7 6.4 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.12 GBG45351.1 - 6 6.1 12.6 0.25 10.6 4.3 2.2 2 0 0 2 2 2 0 NOA36 protein DUF4611 PF15387.6 GBG45351.1 - 7.5 6.8 18.9 0.076 13.2 5.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 GBG45424.1 - 0.00015 21.2 13.4 0.00019 20.9 13.4 1.2 1 0 0 1 1 1 1 NOA36 protein Cwf_Cwc_15 PF04889.12 GBG45424.1 - 0.084 12.6 30.0 2.9 7.5 27.6 2.1 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 GBG45424.1 - 0.11 12.1 12.4 0.11 12.1 12.4 1.2 1 0 0 1 1 1 0 PPP4R2 CNDH2_C PF16858.5 GBG45424.1 - 0.13 12.1 5.9 0.12 12.2 5.9 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BUD22 PF09073.10 GBG45424.1 - 0.14 11.5 15.9 0.16 11.3 15.9 1.1 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.10 GBG45424.1 - 0.44 11.3 18.6 0.89 10.3 18.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TFB6 PF17110.5 GBG45424.1 - 0.47 10.2 7.4 0.64 9.7 7.4 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2457 PF10446.9 GBG45424.1 - 0.55 9.3 28.0 0.68 9.0 28.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 GBG45424.1 - 0.67 9.9 13.5 0.67 9.9 13.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 GBG45424.1 - 0.73 7.9 28.4 0.9 7.6 28.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG45424.1 - 0.87 9.0 19.6 0.8 9.1 19.6 1.2 1 0 0 1 1 1 0 SDA1 DUF2796 PF10986.8 GBG45424.1 - 2.4 8.1 8.5 7.2 6.5 8.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Vfa1 PF08432.10 GBG45424.1 - 2.6 8.3 6.6 3.6 7.9 6.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Astro_capsid_p PF12226.8 GBG45424.1 - 4.1 6.5 17.0 5.1 6.1 17.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 GBG45424.1 - 7.7 4.7 20.0 9.1 4.4 20.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 GBG45424.1 - 7.9 6.3 17.9 12 5.7 17.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NPR3 PF03666.13 GBG45424.1 - 9.3 4.9 7.4 11 4.7 7.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Retrotrans_gag PF03732.17 GBG45432.1 - 0.00016 21.9 3.0 0.00047 20.4 0.1 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein TMEM247 PF15444.6 GBG45432.1 - 0.29 11.1 0.1 0.29 11.1 0.1 1.6 2 0 0 2 2 2 0 Transmembrane protein 247 SlyX PF04102.12 GBG45453.1 - 0.13 12.9 0.1 4.7 7.9 0.1 2.4 2 0 0 2 2 2 0 SlyX Pkinase PF00069.25 GBG45461.1 - 7.3e-20 71.4 0.0 9.2e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG45461.1 - 2.3e-15 56.6 0.0 3e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4192 PF13830.6 GBG45480.1 - 0.15 12.1 7.3 0.2 11.7 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) RT_RNaseH_2 PF17919.1 GBG45518.1 - 2.5e-35 120.5 0.0 5.4e-35 119.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG45518.1 - 2.4e-29 102.4 0.0 3.8e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG45518.1 - 5.1e-29 100.6 0.0 1.9e-28 98.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG45518.1 - 2.6e-10 40.3 0.0 9.5e-10 38.4 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG45518.1 - 6.6e-05 22.7 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG45518.1 - 0.0044 17.6 0.0 0.0094 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG45518.1 - 0.018 15.6 0.0 0.043 14.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG45524.1 - 0.056 13.7 0.8 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein K1377 PF15352.6 GBG45524.1 - 0.057 11.7 2.9 0.078 11.2 2.9 1.1 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy DUF3682 PF12446.8 GBG45524.1 - 0.67 10.4 6.0 1.3 9.5 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Atrophin-1 PF03154.15 GBG45524.1 - 8.7 4.5 9.7 12 4.0 9.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family Presenilin PF01080.17 GBG45547.1 - 0.12 11.1 3.0 0.12 11.1 3.0 1.2 1 0 0 1 1 1 0 Presenilin CSRNP_N PF16019.5 GBG45547.1 - 0.88 9.4 8.0 0.073 13.0 3.2 1.5 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DDHD PF02862.17 GBG45547.1 - 1.4 9.1 3.6 1.7 8.7 3.6 1.2 1 0 0 1 1 1 0 DDHD domain PA26 PF04636.13 GBG45547.1 - 3.5 6.5 6.3 4 6.3 6.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) VIR_N PF15912.5 GBG45547.1 - 3.7 7.1 10.2 0.41 10.2 6.0 1.4 2 0 0 2 2 2 0 Virilizer, N-terminal DUF659 PF04937.15 GBG45559.1 - 2.6e-06 27.4 0.0 1.2e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) TAF4 PF05236.14 GBG45559.1 - 0.14 11.8 9.9 0.22 11.2 9.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4360 PF14273.6 GBG45582.1 - 7e-34 117.2 0.2 7.9e-34 117.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Chloroa_b-bind PF00504.21 GBG45596.1 - 8e-43 146.7 0.0 9.5e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein gag-asp_proteas PF13975.6 GBG45640.1 - 9.5e-08 32.5 0.1 2.4e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG45640.1 - 5e-06 27.1 0.1 1.3e-05 25.8 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG45640.1 - 0.0015 18.3 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG45640.1 - 0.0045 16.8 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG45640.1 - 0.035 14.2 1.9 0.065 13.3 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle cNMP_binding PF00027.29 GBG45640.1 - 0.16 12.0 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain zf-4CXXC_R1 PF10497.9 GBG45643.1 - 2.2e-26 92.0 12.5 1.2e-25 89.5 12.5 2.2 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zn-ribbon_14 PF16503.5 GBG45643.1 - 1.3 8.6 10.3 0.89 9.1 3.0 2.8 2 0 0 2 2 2 0 Zinc-ribbon gag-asp_proteas PF13975.6 GBG45668.1 - 6.9e-12 45.8 0.0 1.8e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG45668.1 - 4.2e-10 40.1 0.0 1.1e-09 38.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG45668.1 - 0.00048 20.4 0.0 0.0013 19.0 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG45668.1 - 0.001 18.9 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG45668.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_M41 PF01434.18 GBG45710.1 - 7.1e-20 71.7 0.1 8.3e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M41 YtpI PF14007.6 GBG45730.1 - 0.34 11.1 5.7 6 7.1 3.8 2.5 2 0 0 2 2 2 0 YtpI-like protein Tetraspanin PF00335.20 GBG45730.1 - 0.77 9.4 20.0 0.11 12.1 11.2 2.1 1 1 1 2 2 2 0 Tetraspanin family Trp_oprn_chp PF09534.10 GBG45730.1 - 0.79 9.5 6.6 46 3.7 6.4 2.2 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) rve PF00665.26 GBG45740.1 - 1.1e-13 51.5 0.0 1.8e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain TPT PF03151.16 GBG45767.1 - 1.5e-103 346.2 25.8 2e-76 257.1 13.8 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 GBG45767.1 - 1.1e-11 45.0 30.4 2.8e-10 40.5 13.6 3.2 2 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 GBG45767.1 - 0.00012 21.4 13.5 0.0098 15.1 3.7 2.3 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.15 GBG45767.1 - 0.0048 16.1 1.4 0.012 14.9 1.4 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter Flavodoxin_3 PF12641.7 GBG45767.1 - 0.13 11.9 0.0 18 5.0 0.1 2.2 2 0 0 2 2 2 0 Flavodoxin domain DUF485 PF04341.12 GBG45767.1 - 0.37 10.8 3.1 1.7 8.6 3.1 2.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 UNC119_bdg PF15435.6 GBG45776.1 - 0.065 12.8 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue Presenilin PF01080.17 GBG45785.1 - 1.3 7.7 7.5 1.5 7.5 7.5 1.3 1 0 0 1 1 1 0 Presenilin TadF PF16964.5 GBG45785.1 - 2 8.1 3.9 2.8 7.7 3.9 1.2 1 0 0 1 1 1 0 Putative tight adherence pilin protein F CSRNP_N PF16019.5 GBG45785.1 - 2.8 7.8 10.0 0.67 9.8 3.9 2.0 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus BTB PF00651.31 GBG45808.1 - 6.8e-15 55.3 0.0 1.6e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 GBG45808.1 - 0.036 14.2 0.0 0.095 12.8 0.0 1.7 2 0 0 2 2 2 0 SPRY domain DUF4360 PF14273.6 GBG45843.1 - 7.7e-39 133.4 0.5 9.4e-39 133.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Claudin_2 PF13903.6 GBG45843.1 - 0.071 12.9 0.7 0.11 12.3 0.7 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Retrotrans_gag PF03732.17 GBG45858.1 - 0.0071 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1631 PF07793.11 GBG45858.1 - 0.048 12.1 1.2 0.064 11.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) eIF3g PF12353.8 GBG45858.1 - 0.16 12.4 0.2 0.32 11.4 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G gag-asp_proteas PF13975.6 GBG45865.1 - 2.3e-06 28.1 0.0 6.3e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG45865.1 - 1e-05 26.1 0.0 2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG45865.1 - 2.1e-05 24.3 0.0 7.2e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG45865.1 - 4e-05 23.4 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease PTS_EIIA_2 PF00359.22 GBG45865.1 - 0.063 13.2 0.5 4 7.3 0.1 2.6 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Chlam_PMP PF02415.17 GBG45879.1 - 9.2e-08 32.1 17.7 0.68 10.5 0.4 5.7 5 0 0 5 5 5 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pectinesterase PF01095.19 GBG45923.1 - 1.1e-59 201.6 6.5 1.3e-58 198.1 6.5 2.0 1 1 0 1 1 1 1 Pectinesterase TALPID3 PF15324.6 GBG45923.1 - 1.2 6.7 1.9 1.6 6.3 1.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target RVP_2 PF08284.11 GBG45940.1 - 2e-09 37.3 0.0 4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG45940.1 - 4.5e-09 36.8 0.0 1.2e-08 35.5 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG45940.1 - 1.4e-06 28.7 0.0 3.3e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG45940.1 - 0.0025 17.6 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG45940.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RXT2_N PF08595.11 GBG45952.1 - 1.7 8.7 7.6 0.38 10.8 1.0 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal PspA_IM30 PF04012.12 GBG45997.1 - 4.7e-52 176.7 26.3 6.8e-52 176.2 26.3 1.2 1 0 0 1 1 1 1 PspA/IM30 family DUF4407 PF14362.6 GBG45997.1 - 0.13 11.6 14.5 0.18 11.1 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 GBG45997.1 - 0.55 9.3 12.4 0.74 8.8 12.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1759 PF03564.15 GBG45997.1 - 0.55 10.1 5.9 0.27 11.1 2.6 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) Csm1_N PF18504.1 GBG45997.1 - 0.74 10.2 11.6 0.12 12.8 3.8 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Tankyrase_bdg_C PF15327.6 GBG45997.1 - 1.2 9.5 9.6 1.7 9.1 0.5 2.5 1 1 1 3 3 3 0 Tankyrase binding protein C terminal domain DUF5340 PF17275.2 GBG45997.1 - 1.8 8.8 6.5 4.7 7.4 0.1 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5340) Myb_DNA-bind_4 PF13837.6 GBG46022.1 - 0.00069 19.9 0.7 0.0011 19.3 0.7 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DEK_C PF08766.11 GBG46050.1 - 9.9e-05 22.2 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 DEK C terminal domain VKOR PF07884.14 GBG46091.1 - 1.1e-26 93.5 2.7 2e-26 92.6 2.7 1.4 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Thioredoxin_4 PF13462.6 GBG46091.1 - 0.12 12.6 0.0 2 8.6 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin SDA1 PF05285.12 GBG46104.1 - 6.9e-05 22.4 16.1 7e-05 22.4 16.1 1.0 1 0 0 1 1 1 1 SDA1 Autophagy_N PF03986.13 GBG46104.1 - 0.01 15.8 3.4 0.013 15.5 2.8 1.4 1 1 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF3807 PF12720.7 GBG46104.1 - 0.097 12.9 11.9 0.13 12.5 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Nop14 PF04147.12 GBG46104.1 - 0.78 7.9 22.4 0.99 7.5 22.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG46104.1 - 2.4 6.4 17.8 3.4 5.9 17.8 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG46104.1 - 6.2 6.1 25.3 7.2 5.8 25.3 1.1 1 0 0 1 1 1 0 BUD22 Retrotrans_gag PF03732.17 GBG46169.1 - 0.1 12.9 3.0 0.26 11.6 0.0 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG46171.1 - 7.8e-18 64.8 0.1 1e-17 64.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG46191.1 - 7.3e-20 71.4 0.0 9.2e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG46191.1 - 2.3e-15 56.6 0.0 3e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 GBG46199.1 - 1.5e-10 41.0 0.1 2.9e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Snapin_Pallidin PF14712.6 GBG46199.1 - 0.0077 16.6 5.4 0.18 12.2 0.1 2.8 2 0 0 2 2 2 1 Snapin/Pallidin DUF5095 PF17016.5 GBG46199.1 - 0.55 9.9 1.7 0.52 10.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) Retrotrans_gag PF03732.17 GBG46199.1 - 0.6 10.4 0.0 0.6 10.4 0.0 2.7 2 1 0 2 2 2 0 Retrotransposon gag protein Exonuc_VII_L PF02601.15 GBG46199.1 - 2.4 7.7 8.6 1.5 8.4 6.7 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4140 PF13600.6 GBG46199.1 - 2.4 8.6 12.3 8.1 7.0 0.2 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) HrpB7 PF09486.10 GBG46199.1 - 2.5 8.5 16.6 0.56 10.6 12.6 1.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) CSRNP_N PF16019.5 GBG46200.1 - 2.2 8.1 8.8 0.27 11.1 1.7 2.0 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF659 PF04937.15 GBG46204.1 - 4e-40 137.1 0.0 7.1e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG46204.1 - 8.7e-08 31.9 0.6 8e-07 28.8 0.6 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG46204.1 - 0.029 14.2 3.9 0.096 12.6 3.9 2.0 1 0 0 1 1 1 0 AT hook motif Pox_A_type_inc PF04508.12 GBG46204.1 - 0.21 11.5 2.2 0.63 10.0 2.2 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat rve PF00665.26 GBG46254.1 - 1.7e-16 60.5 0.0 3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG46254.1 - 0.0091 15.8 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG46254.1 - 0.034 14.3 0.4 0.12 12.5 0.4 2.0 2 0 0 2 2 2 0 Integrase zinc binding domain WTX PF09422.10 GBG46279.1 - 0.0064 15.6 2.5 0.007 15.5 2.5 1.1 1 0 0 1 1 1 1 WTX protein CTNNB1_binding PF08347.11 GBG46279.1 - 0.041 14.1 0.1 0.061 13.5 0.0 1.4 1 1 0 1 1 1 0 N-terminal CTNNB1 binding Presenilin PF01080.17 GBG46279.1 - 0.61 8.8 2.1 0.73 8.5 2.1 1.1 1 0 0 1 1 1 0 Presenilin PH_11 PF15413.6 GBG46297.1 - 4.7e-08 33.4 3.0 2.4e-06 27.9 3.0 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GBG46297.1 - 1.8e-07 31.6 0.6 0.00097 19.6 0.1 2.6 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 GBG46297.1 - 0.0063 16.8 8.0 0.18 12.1 0.1 3.7 4 0 0 4 4 4 2 Pleckstrin homology domain PH_3 PF14593.6 GBG46297.1 - 0.027 14.6 0.1 0.085 13.0 0.1 1.8 2 0 0 2 2 2 0 PH domain Med13_C PF06333.12 GBG46297.1 - 0.052 12.8 0.0 0.052 12.8 0.0 1.8 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain PH_13 PF16652.5 GBG46297.1 - 0.2 11.5 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Pleckstrin homology domain Beta_helix PF13229.6 GBG46317.1 - 9.2e-05 22.3 6.4 0.0075 16.1 0.1 2.2 1 1 1 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG46317.1 - 0.0038 17.6 22.0 1.7 9.3 1.5 6.2 5 1 0 5 5 5 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Dynamin_N PF00350.23 GBG46359.1 - 5.8e-11 42.7 0.0 7.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Serglycin PF04360.12 GBG46359.1 - 3.8 7.4 7.5 0.16 11.9 1.0 1.9 1 1 1 2 2 2 0 Serglycin RT_RNaseH_2 PF17919.1 GBG46419.1 - 5.9e-24 84.0 0.0 1e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG46419.1 - 1.1e-14 54.6 0.0 1.9e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG46419.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG46424.1 - 2.5e-39 134.6 0.0 4.3e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2950 PF11453.8 GBG46438.1 - 0.025 13.8 7.3 0.028 13.6 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) PA26 PF04636.13 GBG46438.1 - 0.026 13.4 10.5 0.028 13.4 10.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3138 PF11336.8 GBG46438.1 - 0.45 9.1 2.5 0.54 8.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3629 PF12302.8 GBG46438.1 - 0.46 9.9 7.0 0.63 9.4 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Herpes_UL25 PF01499.16 GBG46438.1 - 2.4 6.6 6.8 2.4 6.6 6.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family RT_RNaseH PF17917.1 GBG46459.1 - 1e-28 99.6 0.0 1.1e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG46459.1 - 4.2e-22 78.1 0.0 6.2e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HTH_micro PF17007.5 GBG46459.1 - 0.015 14.1 0.0 0.015 14.1 0.0 1.0 1 0 0 1 1 1 0 HTH-like Phage_GPO PF05929.11 GBG46459.1 - 0.021 14.4 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Pho88 PF10032.9 GBG46459.1 - 0.16 11.2 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Phosphate transport (Pho88) Pneumo_att_G PF05539.11 GBG46462.1 - 0.043 13.4 2.6 0.052 13.2 2.6 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF4640 PF15480.6 GBG46462.1 - 0.24 11.1 9.5 0.3 10.8 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) Phage_1_1 PF08200.11 GBG46462.1 - 9.8 6.7 12.6 0.34 11.4 1.0 3.6 1 1 2 4 4 4 0 Bacteriophage 1.1 Protein CCD48 PF15799.5 GBG46488.1 - 0.0089 14.4 2.1 0.012 13.9 2.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 HALZ PF02183.18 GBG46488.1 - 0.034 14.4 0.7 0.089 13.0 0.7 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 GBG46488.1 - 0.18 11.6 0.9 0.52 10.1 0.9 1.7 1 0 0 1 1 1 0 Septum formation initiator GvpL_GvpF PF06386.11 GBG46488.1 - 1.7 8.6 4.3 3.7 7.4 4.3 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.15 GBG46488.1 - 2.4 8.3 9.0 0.067 13.3 2.1 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Peptidase_S64 PF08192.11 GBG46492.1 - 0.019 13.5 0.8 0.024 13.1 0.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 HAUS6_N PF14661.6 GBG46492.1 - 1.6 8.3 6.2 0.098 12.2 0.5 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Myb_DNA-bind_4 PF13837.6 GBG46497.1 - 8.4e-09 35.7 1.4 1.2e-08 35.2 1.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG46497.1 - 0.086 12.9 0.9 0.18 11.9 0.9 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RRM_1 PF00076.22 GBG46512.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fer4_21 PF14697.6 GBG46512.1 - 3.7 7.8 5.3 0.5 10.5 0.6 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain C1_4 PF07975.12 GBG46512.1 - 8 6.8 8.0 1.8 8.8 0.7 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain Beta_helix PF13229.6 GBG46523.1 - 9.2e-11 41.8 0.6 3.4e-10 40.0 0.5 1.9 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG46523.1 - 0.036 13.3 0.2 0.11 11.7 0.2 1.7 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Integrase_H2C2 PF17921.1 GBG46531.1 - 3.7e-14 52.6 0.0 9.2e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Pectinesterase PF01095.19 GBG46544.1 - 1.2e-75 254.0 0.2 1.5e-75 253.7 0.2 1.1 1 0 0 1 1 1 1 Pectinesterase Gln-synt_C PF00120.24 GBG46557.1 - 0.00021 20.4 0.0 0.19 10.7 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain GATase_4 PF13230.6 GBG46559.1 - 6.2e-11 41.7 0.1 9.3e-11 41.1 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 GBG46559.1 - 3.6e-09 36.9 0.0 6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain CDC50 PF03381.15 GBG46602.1 - 3.8e-62 210.3 0.0 4.8e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family BAF250_C PF12031.8 GBG46629.1 - 0.035 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa HAUS6_N PF14661.6 GBG46629.1 - 0.058 13.0 0.9 0.081 12.5 0.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MnmE_helical PF12631.7 GBG46629.1 - 0.13 12.4 1.4 0.64 10.2 0.1 2.1 1 1 1 2 2 2 0 MnmE helical domain HHH_9 PF17674.1 GBG46629.1 - 0.17 12.8 2.8 9.2 7.3 1.1 2.5 1 1 1 2 2 2 0 HHH domain Miga PF10265.9 GBG46629.1 - 4.8 6.0 7.2 0.61 9.0 3.6 1.3 2 0 0 2 2 2 0 Mitoguardin SelR PF01641.18 GBG46665.1 - 0.0029 17.7 0.1 0.0037 17.3 0.1 1.2 1 0 0 1 1 1 1 SelR domain RVP_2 PF08284.11 GBG46680.1 - 9.7e-06 25.4 0.0 2.8e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG46680.1 - 1.8e-05 25.3 0.0 5.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG46680.1 - 0.00023 21.0 0.0 0.00052 19.8 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG46680.1 - 0.0027 18.2 0.4 0.016 15.8 0.0 2.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF4392 PF14336.6 GBG46680.1 - 0.095 12.1 1.5 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) DUF2950 PF11453.8 GBG46680.1 - 4.2 6.5 9.9 7.4 5.7 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) PNMA PF14893.6 GBG46729.1 - 0.0015 18.0 0.1 0.002 17.6 0.1 1.1 1 0 0 1 1 1 1 PNMA RasGEF_N PF00618.20 GBG46729.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 RasGEF N-terminal motif Histone PF00125.24 GBG46733.1 - 0.014 15.8 0.8 0.03 14.7 0.8 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 gag_pre-integrs PF13976.6 GBG46733.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 GAG-pre-integrase domain PolyG_pol PF01518.16 GBG46733.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Sigma NS protein Retrotrans_gag PF03732.17 GBG46752.1 - 0.0015 18.8 1.5 0.0061 16.8 0.2 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG46752.1 - 0.003 17.3 0.6 0.0083 15.9 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) gag-asp_proteas PF13975.6 GBG46770.1 - 2e-06 28.3 0.0 7.4e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG46770.1 - 3.6e-05 24.3 0.1 0.00015 22.3 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG46770.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease cNMP_binding PF00027.29 GBG46770.1 - 0.15 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain RVP_2 PF08284.11 GBG46770.1 - 0.2 11.4 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4360 PF14273.6 GBG46778.1 - 1.9e-43 148.4 0.0 2.1e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Dehydrin PF00257.19 GBG46844.1 - 0.11 13.0 0.3 0.17 12.4 0.3 1.2 1 0 0 1 1 1 0 Dehydrin RNA_pol_3_Rpc31 PF11705.8 GBG46844.1 - 1.3 9.2 10.7 2 8.6 10.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 GBG46844.1 - 5.8 4.9 15.7 8.7 4.3 15.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG46844.1 - 7.1 4.7 8.2 8.5 4.4 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH PF17917.1 GBG46884.1 - 1.9e-28 98.8 0.0 2.9e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG46884.1 - 1.6e-27 95.4 0.0 2.8e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SusD-like PF12741.7 GBG46884.1 - 0.042 12.7 0.1 0.051 12.5 0.1 1.1 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein Phage_GPO PF05929.11 GBG46884.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Retrotrans_gag PF03732.17 GBG46891.1 - 2.9e-05 24.3 1.9 0.00014 22.1 0.3 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein CENP-Q PF13094.6 GBG46891.1 - 0.043 14.0 5.4 0.054 13.7 0.2 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MscS_TM PF12794.7 GBG46891.1 - 1.2 8.0 8.7 0.4 9.5 0.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Pkinase PF00069.25 GBG46930.1 - 2e-24 86.4 0.0 2.7e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG46930.1 - 2.1e-20 73.1 0.0 3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RT_RNaseH_2 PF17919.1 GBG46935.1 - 4e-15 55.7 0.1 6.1e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG46935.1 - 1.3e-05 25.4 0.0 0.1 12.9 0.0 2.4 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase UPF0139 PF03669.13 GBG46982.1 - 3.3e-27 94.2 0.0 3.9e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF2232 PF09991.9 GBG46982.1 - 0.0015 17.8 0.2 0.0019 17.4 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) DUF2142 PF09913.9 GBG46982.1 - 0.018 13.9 0.3 0.022 13.6 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) ATP_synth_reg PF14960.6 GBG46982.1 - 0.023 14.1 0.8 0.038 13.5 0.1 1.7 2 0 0 2 2 2 0 ATP synthase regulation zf-CCHC_3 PF13917.6 GBG46998.1 - 0.0097 15.8 2.8 0.027 14.4 2.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG46998.1 - 0.42 10.8 4.8 0.86 9.8 4.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Methyltr_RsmB-F PF01189.17 GBG47023.1 - 6.3e-11 42.3 0.1 3.2e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FoP_duplication PF13865.6 GBG47054.1 - 2.6 8.7 10.5 3.9 8.1 10.5 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RT_RNaseH PF17917.1 GBG47100.1 - 3e-22 78.9 0.0 5.2e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG47100.1 - 6.4e-20 71.1 0.0 1.1e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG47100.1 - 8.3e-17 61.1 2.9 2e-16 59.8 0.4 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG47100.1 - 7.7e-08 32.5 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG47100.1 - 0.00033 20.5 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG47100.1 - 0.0088 16.2 0.1 0.022 15.0 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger BolA PF01722.18 GBG47168.1 - 1.8e-15 57.0 0.0 1.9e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 BolA-like protein Actin PF00022.19 GBG47174.1 - 7.2e-45 153.3 0.0 8e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Actin Thioredoxin PF00085.20 GBG47183.1 - 0.00032 20.6 0.1 0.00098 19.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin DUF4887 PF16228.5 GBG47183.1 - 1 9.5 16.8 2.1 8.5 16.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) RVP_2 PF08284.11 GBG47192.1 - 0.00091 19.0 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG47192.1 - 0.049 13.4 0.1 0.087 12.6 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG47192.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Nop14 PF04147.12 GBG47280.1 - 0.57 8.3 27.4 0.67 8.1 27.4 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG47280.1 - 1.5 7.2 28.0 1.9 6.8 28.0 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 GBG47280.1 - 2.3 6.4 24.1 2.8 6.1 24.1 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG47280.1 - 5.3 6.3 25.4 5.7 6.2 25.4 1.0 1 0 0 1 1 1 0 BUD22 RVT_1 PF00078.27 GBG47295.1 - 1.9e-31 109.3 0.1 2.6e-31 108.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG47295.1 - 0.0056 16.7 0.0 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG47295.1 - 0.1 11.7 0.0 0.26 10.3 0.0 1.4 1 1 1 2 2 2 0 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG47339.1 - 5.9e-25 87.2 0.0 1.2e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG47339.1 - 5.8e-23 81.2 0.0 1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG47339.1 - 3.2e-09 37.0 0.0 9.1e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG47339.1 - 1.1e-07 31.9 2.3 2.2e-07 30.9 2.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Tudor-knot PF11717.8 GBG47339.1 - 0.085 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain RHS_repeat PF05593.14 GBG47348.1 - 4.8e-66 218.5 99.8 1.6e-08 34.9 0.5 17.2 15 4 2 17 17 17 14 RHS Repeat UPF0257 PF06788.13 GBG47348.1 - 1 9.1 5.8 13 5.5 0.3 3.9 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0257) BTB PF00651.31 GBG47387.1 - 2e-14 53.7 0.0 5e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 GBG47387.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 SPRY domain TFIIE-A_C PF11521.8 GBG47387.1 - 0.0054 17.0 5.2 0.0099 16.2 5.2 1.4 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha CENP-R PF06729.12 GBG47387.1 - 0.046 13.6 0.9 0.09 12.7 0.9 1.4 1 0 0 1 1 1 0 Kinetochore component, CENP-R RAB3GAP2_C PF14656.6 GBG47387.1 - 0.053 11.8 0.5 0.073 11.3 0.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Pox_Ag35 PF03286.14 GBG47387.1 - 0.1 12.4 3.4 0.19 11.5 3.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GNAT_acetyltr_2 PF13718.6 GBG47387.1 - 0.11 11.9 0.3 0.17 11.2 0.3 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 EIIBC-GUT_N PF03612.14 GBG47387.1 - 0.14 11.9 1.4 0.53 10.0 1.6 1.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Cytomega_UL84 PF06284.11 GBG47387.1 - 2.3 6.6 4.1 3.8 5.9 4.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Trypan_PARP PF05887.11 GBG47387.1 - 4 7.4 10.1 3.2 7.7 2.8 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Auts2 PF15336.6 GBG47387.1 - 8.3 6.5 6.5 19 5.3 6.5 1.5 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein L71 PF02448.15 GBG47409.1 - 0.052 14.0 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 L71 family UPF0242 PF06785.11 GBG47429.1 - 0.31 11.1 3.0 0.51 10.4 3.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4554 PF15091.6 GBG47429.1 - 6.5 5.5 8.0 8.7 5.1 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Aminotran_1_2 PF00155.21 GBG47430.1 - 2e-67 227.9 0.0 2.6e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GBG47430.1 - 0.00072 18.6 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GBG47430.1 - 0.0058 16.0 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 GBG47430.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 GBG47430.1 - 0.024 13.2 0.0 0.035 12.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 GBG47430.1 - 0.13 11.0 0.0 0.45 9.2 0.0 1.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain gag-asp_proteas PF13975.6 GBG47435.1 - 2.8e-09 37.4 0.0 5.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG47435.1 - 3e-06 27.8 0.0 5.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG47435.1 - 0.00083 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG47435.1 - 0.00094 19.0 0.1 0.0016 18.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.8 GBG47435.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon peptidase Nucleo_P87 PF07267.11 GBG47435.1 - 0.37 9.6 1.1 0.5 9.2 1.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 GBG47435.1 - 0.43 9.3 1.1 0.62 8.8 1.1 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_C14 PF00656.22 GBG47438.1 - 2.7e-27 96.3 0.0 4e-27 95.8 0.0 1.3 1 1 0 1 1 1 1 Caspase domain RVT_1 PF00078.27 GBG47443.1 - 2.7e-25 89.2 0.0 6.7e-25 87.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG47443.1 - 4.5e-23 81.2 0.0 7.9e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG47443.1 - 6.2e-23 81.1 0.0 1.1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG47443.1 - 2.5e-21 75.5 0.2 5.7e-21 74.4 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG47443.1 - 7.5e-06 26.1 0.0 2.9e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG47443.1 - 0.09 13.0 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG47447.1 - 0.026 14.8 10.2 0.047 14.0 0.0 3.7 3 1 0 3 3 3 0 Retrotransposon gag protein FUSC PF04632.12 GBG47447.1 - 0.92 8.0 18.0 1.3 7.5 18.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 GBG47447.1 - 1.3 9.4 9.6 0.22 11.9 1.8 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 GBG47447.1 - 3.1 7.6 18.4 0.44 10.4 2.6 3.7 3 1 0 3 3 3 0 Septum formation initiator FtsL PF04999.13 GBG47447.1 - 3.4 7.7 12.4 6.2 6.9 1.6 2.6 2 0 0 2 2 2 0 Cell division protein FtsL HIP1_clath_bdg PF16515.5 GBG47447.1 - 3.5 8.3 27.0 0.073 13.7 6.0 3.5 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc24 PF08286.11 GBG47447.1 - 3.7 7.9 14.8 0.57 10.4 1.5 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Retrotrans_gag PF03732.17 GBG47467.1 - 0.00032 20.9 0.2 0.00064 19.9 0.2 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG47467.1 - 0.013 15.3 0.9 0.013 15.3 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Sclerostin PF05463.11 GBG47467.1 - 0.041 13.6 1.0 0.64 9.7 0.1 2.1 1 1 1 2 2 2 0 Sclerostin (SOST) Nucleoside_tran PF01733.18 GBG47488.1 - 3.7e-50 171.1 17.0 1e-31 110.5 5.3 2.5 3 0 0 3 3 3 2 Nucleoside transporter RT_RNaseH_2 PF17919.1 GBG47503.1 - 3.8e-30 103.9 0.0 6.7e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG47503.1 - 9.2e-27 93.4 0.1 1.7e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG47503.1 - 2.3e-18 66.1 0.4 4.7e-18 65.1 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG47503.1 - 8.2e-15 55.0 0.0 1.9e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG47503.1 - 0.003 17.3 0.2 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG47503.1 - 0.0071 16.5 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG47503.1 - 0.11 12.4 0.3 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG47513.1 - 1.4e-31 109.7 0.1 2.2e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG47513.1 - 2.4e-25 88.5 0.0 5.6e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG47513.1 - 2.2e-23 82.5 0.0 5.6e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG47513.1 - 1.8e-16 60.0 0.1 4.3e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG47513.1 - 2.8e-09 37.2 0.0 1e-08 35.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain HIP1_clath_bdg PF16515.5 GBG47549.1 - 0.0031 18.1 3.4 0.0031 18.1 3.4 3.1 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 GBG47549.1 - 0.086 13.3 1.2 0.61 10.6 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GBG47549.1 - 0.16 11.3 13.2 0.61 9.4 7.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 GBG47549.1 - 2.7 8.1 16.6 0.21 11.7 1.7 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding SIMPL PF04402.14 GBG47551.1 - 0.034 14.6 0.2 0.039 14.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Retrotrans_gag PF03732.17 GBG47602.1 - 0.0011 19.2 1.5 0.0051 17.1 0.1 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein Sulfatase_C PF14707.6 GBG47602.1 - 0.048 14.4 0.5 0.12 13.1 0.5 1.7 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase FUSC PF04632.12 GBG47602.1 - 3.8 5.9 8.3 5.3 5.4 7.2 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family LPP PF04728.13 GBG47602.1 - 3.8 8.0 5.6 25 5.4 0.1 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF4404 PF14357.6 GBG47602.1 - 5.3 7.8 9.8 0.28 11.9 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF2228 PF10228.9 GBG47622.1 - 0.025 14.3 4.0 0.33 10.7 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) ADIP PF11559.8 GBG47622.1 - 1.5 8.9 14.4 1.2 9.2 11.8 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF444 PF04285.12 GBG47622.1 - 2.9 6.9 10.6 4 6.4 10.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF444) ARID PF01388.21 GBG47658.1 - 1.8e-08 34.9 0.0 2.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain GLTT PF01744.20 GBG47663.1 - 3.1e-09 36.3 0.5 0.00019 21.1 0.1 2.4 1 1 0 2 2 2 2 GLTT repeat (6 copies) FAM76 PF16046.5 GBG47667.1 - 0.063 12.6 9.8 0.086 12.2 9.8 1.1 1 0 0 1 1 1 0 FAM76 protein DUF3573 PF12097.8 GBG47667.1 - 0.25 10.1 0.3 0.39 9.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) CENP-F_leu_zip PF10473.9 GBG47667.1 - 0.45 10.5 0.1 0.45 10.5 0.1 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4666 PF15697.5 GBG47667.1 - 2.8 8.7 6.4 1.1 9.9 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) DUF5523 PF17661.1 GBG47667.1 - 5.8 6.5 11.6 1.4 8.5 8.4 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Retrotrans_gag PF03732.17 GBG47709.1 - 0.0042 17.3 3.5 0.017 15.4 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG47709.1 - 0.01 16.3 3.7 0.72 10.4 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YPEB PF14620.6 GBG47709.1 - 0.015 14.6 1.7 0.025 14.0 1.7 1.2 1 0 0 1 1 1 0 YpeB sporulation HIP1_clath_bdg PF16515.5 GBG47709.1 - 0.017 15.7 6.8 0.017 15.7 6.8 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Inhibitor_I29 PF08246.12 GBG47709.1 - 0.06 13.8 0.3 0.2 12.1 0.3 1.9 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Syntaxin-6_N PF09177.11 GBG47709.1 - 0.098 13.2 2.7 1.7 9.3 1.9 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal SPACA9 PF15120.6 GBG47709.1 - 0.12 12.1 1.4 0.28 10.9 1.4 1.6 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF1664 PF07889.12 GBG47709.1 - 0.17 12.0 2.1 6.8 6.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sec2p PF06428.11 GBG47709.1 - 0.22 11.5 5.6 5 7.2 3.7 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Spc24 PF08286.11 GBG47709.1 - 0.24 11.7 3.9 2.1 8.7 2.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.6 GBG47709.1 - 0.27 11.7 6.0 0.29 11.6 2.8 2.3 2 0 0 2 2 2 0 Snapin/Pallidin BLOC1_2 PF10046.9 GBG47709.1 - 0.53 10.6 6.6 0.22 11.9 2.5 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 GBG47709.1 - 0.79 10.4 7.6 1 10.0 4.8 2.5 2 0 0 2 2 2 0 SlyX ZapB PF06005.12 GBG47709.1 - 0.81 10.2 8.3 4.4 7.8 6.2 2.8 3 0 0 3 3 3 0 Cell division protein ZapB DUF4407 PF14362.6 GBG47709.1 - 3.2 7.0 6.2 8.7 5.6 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 GBG47709.1 - 5.9 6.7 8.2 1.3 8.9 3.8 2.2 2 0 0 2 2 2 0 Septum formation initiator CLZ PF16526.5 GBG47709.1 - 7.8 6.9 8.0 6.4 7.2 4.2 2.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FliD_N PF02465.18 GBG47709.1 - 8 7.2 6.7 5 7.9 1.6 2.7 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF1115 PF06544.12 GBG47714.1 - 0.42 10.7 12.9 0.43 10.7 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Prothymosin PF03247.14 GBG47714.1 - 0.89 10.0 31.3 0.98 9.9 31.3 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family FAM176 PF14851.6 GBG47714.1 - 1 9.0 13.4 1.2 8.8 13.4 1.2 1 0 0 1 1 1 0 FAM176 family DNApol_Exo PF18136.1 GBG47714.1 - 1.3 8.1 7.2 1.3 8.1 7.2 1.0 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain DUF2052 PF09747.9 GBG47714.1 - 1.6 8.8 20.3 1.5 8.9 20.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RPN2_C PF18004.1 GBG47714.1 - 2 8.3 17.1 2.2 8.2 17.1 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 GBG47714.1 - 3.2 7.0 17.3 3.3 6.9 17.3 1.0 1 0 0 1 1 1 0 NOA36 protein CPSF100_C PF13299.6 GBG47714.1 - 4.1 7.6 10.0 4.3 7.5 10.0 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 GBG47714.1 - 4.2 5.6 17.2 4.2 5.6 17.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 GBG47714.1 - 4.6 7.6 8.2 4.4 7.7 8.2 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 Paf1 PF03985.13 GBG47714.1 - 4.8 6.1 23.1 4.3 6.2 23.1 1.0 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 GBG47714.1 - 5.1 6.4 18.8 4.8 6.5 18.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT IDO PF01231.18 GBG47714.1 - 5.1 5.8 6.7 5.1 5.8 6.7 1.0 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase TFB6 PF17110.5 GBG47714.1 - 5.3 6.8 12.7 5.5 6.7 12.7 1.0 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 GBG47714.1 - 6.2 4.8 23.2 6.1 4.8 23.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 GBG47714.1 - 6.2 5.5 7.6 6 5.5 7.6 1.0 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 GBG47714.1 - 6.9 6.4 7.2 6.8 6.4 7.2 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pox_Ag35 PF03286.14 GBG47714.1 - 6.9 6.4 15.6 6.8 6.4 15.6 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Usp PF00582.26 GBG47714.1 - 8.4 6.9 9.8 8.3 6.9 9.8 1.0 1 0 0 1 1 1 0 Universal stress protein family Retrotrans_gag PF03732.17 GBG47726.1 - 2e-06 28.0 2.2 0.0046 17.2 0.0 3.4 3 0 0 3 3 3 2 Retrotransposon gag protein Baculo_PEP_C PF04513.12 GBG47726.1 - 0.11 12.6 0.9 0.26 11.3 0.9 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 GBG47726.1 - 0.2 12.3 2.2 15 6.3 0.3 2.8 2 0 0 2 2 2 0 SlyX zf-RVT PF13966.6 GBG47753.1 - 4.5e-06 27.3 3.9 4.5e-06 27.3 3.9 2.1 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase Chromo PF00385.24 GBG47760.1 - 2.1e-11 43.5 0.1 3.8e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG47766.1 - 1.3e-33 115.0 0.0 2.6e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG47766.1 - 1.5e-29 102.3 0.1 3.8e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG47766.1 - 5.4e-19 68.0 0.1 1.1e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG47766.1 - 8.5e-16 58.2 0.1 3.2e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG47766.1 - 0.034 14.3 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF2584 PF10763.9 GBG47766.1 - 0.078 13.2 0.1 9.4 6.5 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2584) VAPB_antitox PF02697.14 GBG47766.1 - 0.45 11.3 2.5 3.8 8.4 2.2 2.7 2 1 0 2 2 2 0 Putative antitoxin FAM72 PF14976.6 GBG47777.1 - 0.047 13.8 0.3 0.047 13.8 0.3 1.0 1 0 0 1 1 1 0 FAM72 protein Sgf11 PF08209.11 GBG47777.1 - 0.098 12.2 1.5 0.63 9.7 0.1 2.1 1 1 1 2 2 2 0 Sgf11 (transcriptional regulation protein) RasGEF_N PF00618.20 GBG47784.1 - 0.015 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 RasGEF N-terminal motif PNMA PF14893.6 GBG47784.1 - 0.017 14.5 0.8 0.022 14.2 0.0 1.5 2 0 0 2 2 2 0 PNMA SIMPL PF04402.14 GBG47794.1 - 0.011 16.2 0.1 0.012 16.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) SDA1 PF05285.12 GBG47800.1 - 0.67 9.3 76.9 0.91 8.9 76.9 1.2 1 0 0 1 1 1 0 SDA1 Mis12 PF05859.12 GBG47818.1 - 1.1 9.3 8.1 3.9 7.5 8.2 2.0 1 1 0 1 1 1 0 Mis12 protein LMBR1 PF04791.16 GBG47818.1 - 5.6 5.8 7.6 7.2 5.4 7.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RVT_1 PF00078.27 GBG47849.1 - 7.9e-25 87.7 0.1 1.1e-24 87.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG47849.1 - 1.3e-06 29.0 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG47849.1 - 8.3e-06 26.3 0.0 1.4e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG47849.1 - 1.8e-05 24.6 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG47849.1 - 0.0002 21.1 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG47849.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease ANAPC4_WD40 PF12894.7 GBG47857.1 - 0.14 12.5 0.0 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CobT PF06213.12 GBG47862.1 - 0.21 10.9 28.4 0.25 10.7 28.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4604 PF15377.6 GBG47862.1 - 6.9 7.1 33.9 10 6.5 33.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF4050 PF13259.6 GBG47862.1 - 8.1 6.7 15.3 12 6.2 15.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Sel1 PF08238.12 GBG47892.1 - 3.1e-30 103.9 14.4 2.9e-07 30.9 0.1 5.5 5 0 0 5 5 5 5 Sel1 repeat PDZ_6 PF17820.1 GBG47892.1 - 3.8e-12 45.8 0.3 1.1e-11 44.3 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 GBG47892.1 - 4.7e-10 39.7 0.1 1.8e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PP2C_2 PF13672.6 GBG47892.1 - 5.5e-10 39.2 0.1 1.1e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PDZ PF00595.24 GBG47892.1 - 6e-08 32.9 0.1 1.2e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 PDZ domain SpoIIE PF07228.12 GBG47892.1 - 1.8e-06 28.0 0.3 9.8e-06 25.6 0.3 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GBG47892.1 - 0.0044 16.7 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C MIT PF04212.18 GBG47892.1 - 0.017 15.2 3.9 0.54 10.4 0.1 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 GBG47892.1 - 0.035 14.7 6.8 5.5 7.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1376 PF07120.11 GBG47892.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) TPR_7 PF13176.6 GBG47892.1 - 0.19 11.8 4.1 12 6.2 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Angiomotin_C PF12240.8 GBG47896.1 - 0.02 14.5 0.2 0.02 14.5 0.2 1.8 3 0 0 3 3 3 0 Angiomotin C terminal BRE1 PF08647.11 GBG47896.1 - 0.042 13.9 0.5 0.092 12.8 0.5 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Rieske PF00355.26 GBG47937.1 - 6.3e-18 64.5 0.0 1.9e-17 63.0 0.0 1.8 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG47937.1 - 8.1e-10 38.7 0.1 2.1e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 Pheophorbide a oxygenase CDH-cyt PF16010.5 GBG47937.1 - 0.26 11.0 2.0 0.26 10.9 0.3 1.8 2 0 0 2 2 2 0 Cytochrome domain of cellobiose dehydrogenase RT_RNaseH_2 PF17919.1 GBG47974.1 - 1.9e-23 82.4 0.0 3.2e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG47974.1 - 7.9e-23 80.7 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG47974.1 - 3.4e-09 36.9 0.0 1.1e-08 35.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG47974.1 - 3e-07 30.4 2.2 5.7e-07 29.6 2.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Trypsin PF00089.26 GBG47976.1 - 5.2e-07 29.7 0.0 7.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin Retrotrans_gag PF03732.17 GBG47988.1 - 2e-06 28.0 2.2 0.0046 17.2 0.0 3.4 3 0 0 3 3 3 2 Retrotransposon gag protein Baculo_PEP_C PF04513.12 GBG47988.1 - 0.11 12.6 0.9 0.26 11.3 0.9 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 GBG47988.1 - 0.2 12.3 2.2 15 6.3 0.3 2.8 2 0 0 2 2 2 0 SlyX YL1 PF05764.13 GBG48025.1 - 0.0014 18.8 2.7 0.0024 18.0 2.7 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GBG48025.1 - 0.025 14.3 1.2 0.035 13.8 1.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PRIMA1 PF16101.5 GBG48025.1 - 0.43 10.6 2.6 4 7.5 0.3 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CDC45 PF02724.14 GBG48025.1 - 0.9 7.8 3.6 1.2 7.3 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG48025.1 - 1.4 7.0 3.2 1.7 6.8 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 GBG48089.1 - 4.4e-20 72.1 0.0 6.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG48089.1 - 5e-19 68.6 0.0 9.3e-19 67.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FAM184 PF15665.5 GBG48089.1 - 0.00093 19.0 18.6 0.0022 17.8 18.7 1.6 1 1 0 1 1 1 1 Family with sequence similarity 184, A and B Shugoshin_N PF07558.11 GBG48089.1 - 0.012 15.5 1.7 0.012 15.5 1.7 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Kinase-like PF14531.6 GBG48089.1 - 0.021 14.2 0.0 0.06 12.6 0.0 1.8 1 1 1 2 2 2 0 Kinase-like Phage_GP20 PF06810.11 GBG48089.1 - 0.28 11.0 3.3 0.21 11.4 1.3 1.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 GBG48089.1 - 3.3 8.2 6.7 79 3.8 0.1 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) GAS PF13851.6 GBG48089.1 - 5.4 6.3 14.4 0.92 8.8 7.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Pkinase_Tyr PF07714.17 GBG48095.1 - 2.2e-25 89.4 0.0 5e-25 88.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG48095.1 - 6.1e-24 84.8 0.0 1.1e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Shugoshin_N PF07558.11 GBG48095.1 - 0.0014 18.4 5.8 0.023 14.6 1.9 3.4 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region GAS PF13851.6 GBG48095.1 - 0.0026 17.1 19.7 0.0044 16.4 9.9 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding UreE_C PF05194.12 GBG48095.1 - 0.014 15.9 0.3 0.67 10.5 0.0 2.6 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain DMPK_coil PF08826.10 GBG48095.1 - 0.018 15.1 1.5 0.018 15.1 1.5 3.0 3 0 0 3 3 3 0 DMPK coiled coil domain like EzrA PF06160.12 GBG48095.1 - 0.02 13.1 3.9 0.032 12.4 3.9 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Kinase-like PF14531.6 GBG48095.1 - 0.037 13.4 0.0 0.1 11.9 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Phage_GP20 PF06810.11 GBG48095.1 - 0.12 12.2 2.3 0.16 11.8 1.2 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 GBG48095.1 - 0.12 12.4 21.6 0.49 10.4 8.6 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 GBG48095.1 - 0.16 12.4 6.6 45 4.5 0.0 4.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 GBG48095.1 - 0.94 9.5 19.9 0.15 12.1 3.8 3.8 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 GBG48095.1 - 1.3 9.2 16.7 0.47 10.6 4.0 3.3 3 0 0 3 3 3 0 bZIP transcription factor HOOK PF05622.12 GBG48095.1 - 1.6 6.8 14.9 2.4 6.2 14.9 1.2 1 0 0 1 1 1 0 HOOK protein ATG16 PF08614.11 GBG48095.1 - 2.7 8.2 19.6 3.8 7.7 8.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FAM184 PF15665.5 GBG48095.1 - 3.3 7.4 17.7 8.7 6.1 17.7 1.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B ADIP PF11559.8 GBG48095.1 - 4.8 7.3 16.5 6.4 6.9 9.3 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Gln-synt_C PF00120.24 GBG48109.1 - 1.7e-15 56.9 0.0 1.6e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG48109.1 - 4.2e-11 42.4 0.0 7.7e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain CSRNP_N PF16019.5 GBG48141.1 - 0.89 9.4 12.5 0.068 13.1 3.1 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus FAM60A PF15396.6 GBG48141.1 - 1.9 8.5 18.1 9.1 6.2 18.1 1.9 1 1 0 1 1 1 0 Protein Family FAM60A Nop14 PF04147.12 GBG48180.1 - 3.8 5.6 7.6 3.7 5.6 7.6 1.0 1 0 0 1 1 1 0 Nop14-like family zf-RVT PF13966.6 GBG48192.1 - 3.8e-06 27.5 6.9 0.00028 21.5 7.0 3.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 GBG48192.1 - 0.13 11.7 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 GBG48219.1 - 0.11 11.3 6.7 0.13 11.0 6.7 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG48219.1 - 4.2 5.5 14.3 5.7 5.1 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 GBG48219.1 - 4.9 6.1 10.2 6.6 5.6 10.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Retrotrans_gag PF03732.17 GBG48237.1 - 0.021 15.1 2.1 0.49 10.7 0.1 3.1 2 1 1 3 3 3 0 Retrotransposon gag protein Sporozoite_P67 PF05642.11 GBG48237.1 - 0.035 12.2 4.8 0.055 11.6 4.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tmemb_cc2 PF10267.9 GBG48237.1 - 0.083 12.0 3.9 0.025 13.7 1.0 1.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein PEARLI-4 PF05278.12 GBG48237.1 - 0.1 12.2 2.2 0.22 11.1 2.2 1.6 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) ApoO PF09769.9 GBG48237.1 - 0.11 12.5 0.9 19 5.3 0.4 2.6 2 0 0 2 2 2 0 Apolipoprotein O YlqD PF11068.8 GBG48237.1 - 0.8 10.1 4.8 0.69 10.3 1.5 2.2 2 0 0 2 2 2 0 YlqD protein Retrotrans_gag PF03732.17 GBG48244.1 - 0.00049 20.3 0.2 0.00049 20.3 0.2 2.9 4 0 0 4 4 4 1 Retrotransposon gag protein Pec_lyase_C PF00544.19 GBG48249.1 - 7.1e-32 110.7 0.3 3.2e-31 108.6 0.3 1.8 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG48249.1 - 1.8e-05 24.7 0.8 7.7e-05 22.6 0.7 2.0 1 1 1 2 2 2 2 Right handed beta helix region RVT_1 PF00078.27 GBG48250.1 - 4e-25 88.6 0.0 5.5e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG48250.1 - 1.3e-11 44.4 0.0 2.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG48250.1 - 0.00012 22.3 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GUCT PF08152.12 GBG48300.1 - 0.043 14.1 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 GUCT (NUC152) domain Filament PF00038.21 GBG48300.1 - 0.047 13.3 6.5 0.1 12.2 1.8 2.6 2 1 0 2 2 2 0 Intermediate filament protein DUF4600 PF15372.6 GBG48300.1 - 0.11 12.9 3.4 0.11 12.9 1.6 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) UPF0449 PF15136.6 GBG48300.1 - 0.12 12.8 1.2 0.62 10.6 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 GAS PF13851.6 GBG48300.1 - 0.29 10.4 1.8 0.74 9.1 0.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 GBG48300.1 - 0.36 10.9 6.1 3.4 7.7 0.8 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.6 GBG48300.1 - 2.6 8.5 11.1 1.2e+02 3.3 6.5 3.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 GBG48300.1 - 2.9 8.4 7.1 1.6 9.3 3.8 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Chromo PF00385.24 GBG48341.1 - 8.1e-13 48.1 0.0 1.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.14 GBG48373.1 - 0.00037 20.2 0.1 0.0008 19.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG48407.1 - 2.8e-09 37.4 0.0 5.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG48407.1 - 3e-06 27.8 0.0 5.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG48407.1 - 0.00083 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG48407.1 - 0.00094 19.0 0.1 0.0016 18.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.8 GBG48407.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon peptidase Nucleo_P87 PF07267.11 GBG48407.1 - 0.37 9.6 1.1 0.5 9.2 1.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 GBG48407.1 - 0.43 9.3 1.1 0.62 8.8 1.1 1.1 1 0 0 1 1 1 0 Presenilin SNARE PF05739.19 GBG48415.1 - 8.2e-08 32.1 2.1 2.3e-07 30.7 2.1 1.8 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 GBG48415.1 - 0.038 12.0 0.2 0.054 11.5 0.2 1.2 1 0 0 1 1 1 0 Prominin DUF745 PF05335.13 GBG48415.1 - 0.061 13.0 3.3 4.7 6.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) KxDL PF10241.9 GBG48415.1 - 0.17 12.2 5.0 0.32 11.3 1.9 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 GBG48415.1 - 0.22 12.1 2.0 2.1 8.9 0.0 2.6 2 2 0 2 2 2 0 Syntaxin 6, N-terminal DUF1612 PF07756.12 GBG48439.1 - 1.9e-21 76.6 5.2 4.9e-21 75.3 5.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1612) HTH_13 PF11972.8 GBG48439.1 - 1.2e-11 44.5 0.0 2.8e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 HTH DNA binding domain HTH_1 PF00126.27 GBG48439.1 - 0.00088 19.2 0.1 0.0076 16.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Fic_N PF13784.6 GBG48439.1 - 0.001 19.1 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family N-terminal Tnp_DNA_bind PF14706.6 GBG48439.1 - 0.0018 18.1 0.1 0.0062 16.4 0.1 1.9 1 0 0 1 1 1 1 Transposase DNA-binding TMEM191C PF15194.6 GBG48439.1 - 0.068 13.4 0.6 4 7.6 0.0 2.7 3 0 0 3 3 3 0 TMEM191C family Phage_integrase PF00589.22 GBG48440.1 - 2.6e-20 72.9 0.0 3.9e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 GBG48440.1 - 0.00024 21.3 0.3 0.001 19.3 0.1 2.2 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_2 PF12834.7 GBG48440.1 - 0.0069 17.0 0.4 0.033 14.9 0.0 2.2 2 1 1 3 3 3 1 Phage integrase, N-terminal EutC PF05985.11 GBG48440.1 - 0.062 12.6 0.1 0.098 11.9 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) RPN2_C PF18004.1 GBG48501.1 - 0.097 12.6 25.5 0.11 12.4 25.5 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FYDLN_acid PF09538.10 GBG48501.1 - 0.24 12.1 22.7 0.27 11.9 22.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) ATAD4 PF15321.6 GBG48501.1 - 0.39 12.1 8.3 0.46 11.9 8.3 1.1 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Pox_Ag35 PF03286.14 GBG48501.1 - 0.42 10.4 23.9 0.46 10.3 23.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3306 PF11748.8 GBG48501.1 - 0.79 10.6 19.2 0.88 10.5 19.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Eapp_C PF10238.9 GBG48501.1 - 1.2 9.2 12.7 1.4 9.0 12.7 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein Mpp10 PF04006.12 GBG48501.1 - 1.5 7.2 33.1 1.5 7.2 33.1 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG48501.1 - 1.5 7.0 34.0 1.5 6.9 34.0 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG48501.1 - 1.7 6.6 40.6 1.7 6.6 40.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Cellulose_synt PF03552.14 GBG48501.1 - 1.8 6.9 10.4 1.8 6.9 10.4 1.0 1 0 0 1 1 1 0 Cellulose synthase BUD22 PF09073.10 GBG48501.1 - 1.9 7.7 28.1 2 7.7 28.1 1.0 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.13 GBG48501.1 - 2.3 7.1 33.8 2.5 7.0 33.8 1.0 1 0 0 1 1 1 0 Paf1 Cwf_Cwc_15 PF04889.12 GBG48501.1 - 2.4 7.8 26.5 2.5 7.8 26.5 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_Rpc4 PF05132.14 GBG48501.1 - 3.2 8.2 13.7 3.4 8.1 13.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 TRAP_alpha PF03896.16 GBG48501.1 - 3.3 6.9 22.6 3.5 6.7 22.6 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SpoIIP PF07454.11 GBG48501.1 - 3.3 7.1 18.0 3.2 7.1 18.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 GBG48501.1 - 3.3 6.4 15.7 3.4 6.3 15.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 GBG48501.1 - 3.6 6.9 33.4 3.8 6.8 33.4 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CTU2 PF10288.9 GBG48501.1 - 4 7.7 11.9 4.8 7.5 11.9 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 RR_TM4-6 PF06459.12 GBG48501.1 - 4.1 7.1 23.7 4.2 7.1 23.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFB6 PF17110.5 GBG48501.1 - 4.9 6.9 18.8 6.1 6.6 18.8 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Afi1 PF07792.12 GBG48501.1 - 6.1 7.3 18.5 6.7 7.2 18.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 GBG48501.1 - 6.7 5.4 16.4 6.6 5.4 16.4 1.0 1 0 0 1 1 1 0 Presenilin MRNIP PF15749.5 GBG48501.1 - 6.7 7.5 16.0 9 7.1 16.0 1.3 1 0 0 1 1 1 0 MRN-interacting protein DDRGK PF09756.9 GBG48501.1 - 6.7 6.2 34.4 7.4 6.1 34.4 1.0 1 0 0 1 1 1 0 DDRGK domain Slu7 PF11708.8 GBG48501.1 - 7 6.3 22.8 7.3 6.3 22.8 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor V_ATPase_I PF01496.19 GBG48501.1 - 7.1 4.4 17.2 7.5 4.3 17.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 GBG48501.1 - 8.2 5.3 15.4 8.1 5.3 15.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 GBG48501.1 - 8.5 6.1 16.2 9.7 5.9 16.2 1.0 1 0 0 1 1 1 0 Connexin RNA_pol_3_Rpc31 PF11705.8 GBG48501.1 - 8.9 6.5 38.3 12 6.1 38.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM60A PF15396.6 GBG48501.1 - 9.4 6.2 9.6 9.5 6.2 9.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A MCM_bind PF09739.9 GBG48501.1 - 9.8 4.5 17.2 9.4 4.5 17.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Nop53 PF07767.11 GBG48501.1 - 9.9 5.4 34.2 9.3 5.5 34.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4360 PF14273.6 GBG48545.1 - 3.5e-42 144.3 0.0 4e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CENP-Q PF13094.6 GBG48565.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit MSA-2c PF12238.8 GBG48565.1 - 1.2 9.1 14.5 2.3 8.2 14.5 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF2457 PF10446.9 GBG48565.1 - 6.3 5.8 10.9 9.1 5.3 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Retrotrans_gag PF03732.17 GBG48593.1 - 0.0043 17.3 0.9 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein T6PP_N PF18572.1 GBG48593.1 - 0.08 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Seryl_tRNA_N PF02403.22 GBG48593.1 - 0.13 12.5 0.4 0.13 12.5 0.4 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-RanBP PF00641.18 GBG48609.1 - 5.7e-08 31.9 8.6 1.9e-07 30.2 3.1 2.1 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 GBG48609.1 - 0.22 11.6 0.3 0.22 11.6 0.3 3.0 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger PHD PF00628.29 GBG48609.1 - 0.25 11.3 5.2 0.75 9.7 4.6 2.1 1 1 1 2 2 2 0 PHD-finger Na_sulph_symp PF00939.19 GBG48681.1 - 0.023 13.7 3.7 0.023 13.8 3.7 1.0 1 0 0 1 1 1 0 Sodium:sulfate symporter transmembrane region DC_STAMP PF07782.13 GBG48700.1 - 0.095 12.5 0.1 0.099 12.5 0.1 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein HemY_N PF07219.13 GBG48700.1 - 8.8 6.6 6.8 23 5.3 6.8 1.6 1 1 0 1 1 1 0 HemY protein N-terminus zf-CCHC PF00098.23 GBG48710.1 - 3.6e-08 33.1 2.4 7.1e-08 32.2 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG48710.1 - 0.021 14.5 0.3 0.036 13.8 0.3 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 GBG48710.1 - 0.024 14.4 1.5 0.051 13.4 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle TALPID3 PF15324.6 GBG48710.1 - 0.062 11.0 0.9 0.073 10.7 0.9 1.1 1 0 0 1 1 1 0 Hedgehog signalling target RVT_1 PF00078.27 GBG48741.1 - 5.1e-27 94.8 0.1 1.6e-26 93.2 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG48741.1 - 3.1e-23 81.7 0.0 1e-22 80.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG48741.1 - 1e-22 80.4 0.0 4.1e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG48741.1 - 0.013 15.8 4.7 0.046 14.0 0.0 3.8 5 0 0 5 5 5 0 Retrotransposon gag protein RVP_2 PF08284.11 GBG48741.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease HIP1_clath_bdg PF16515.5 GBG48741.1 - 0.061 13.9 0.7 0.061 13.9 0.7 2.5 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4618 PF15397.6 GBG48741.1 - 0.26 10.7 1.5 0.28 10.6 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) LPP PF04728.13 GBG48741.1 - 0.77 10.2 2.7 3.6 8.1 0.1 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF3930 PF13067.6 GBG48752.1 - 0.15 12.3 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) RT_RNaseH_2 PF17919.1 GBG48754.1 - 2.1e-22 79.0 0.0 6.7e-22 77.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG48754.1 - 1.2e-10 41.6 0.0 3.3e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG48754.1 - 2e-08 34.0 0.1 3.2e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG48778.1 - 0.00058 20.1 1.3 0.0022 18.2 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG48778.1 - 0.022 15.4 1.6 0.046 14.3 0.7 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RVT_1 PF00078.27 GBG48803.1 - 3.4e-35 121.6 0.0 5.9e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG48803.1 - 1e-31 108.9 0.0 2e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG48803.1 - 3e-27 95.0 0.0 5.4e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG48803.1 - 1.1e-17 63.9 0.0 2.2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG48803.1 - 9.2e-09 35.5 0.0 1.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG48803.1 - 0.0043 17.2 0.0 0.0096 16.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Rhamno_transf PF11316.8 GBG48803.1 - 0.062 12.7 0.1 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative rhamnosyl transferase Chromo PF00385.24 GBG48902.1 - 0.079 12.9 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain HNH_3 PF13392.6 GBG48902.1 - 0.15 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease zf-CCHC_3 PF13917.6 GBG48935.1 - 0.00056 19.8 1.5 0.0012 18.8 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG48935.1 - 0.01 16.1 0.1 0.022 15.1 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein DUF3863 PF12979.7 GBG48935.1 - 0.023 13.5 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) zf-CCHC PF00098.23 GBG48935.1 - 1.5 9.0 3.7 2.8 8.2 3.7 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2730 PF10805.8 GBG48938.1 - 0.011 15.8 1.2 2.3 8.4 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) SlyX PF04102.12 GBG48938.1 - 0.033 14.8 0.8 0.033 14.8 0.8 3.3 2 2 1 3 3 3 0 SlyX TolA_bind_tri PF16331.5 GBG48938.1 - 0.26 11.4 8.9 0.046 13.8 3.3 2.6 2 1 1 3 3 3 0 TolA binding protein trimerisation PFEMP PF03011.15 GBG48938.1 - 1.6 9.4 6.5 0.52 11.0 3.8 1.5 2 0 0 2 2 2 0 PFEMP DBL domain CENP-X PF09415.10 GBG49008.1 - 0.17 12.2 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF3138 PF11336.8 GBG49012.1 - 0.027 13.1 1.5 0.032 12.8 1.3 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) Rotamase_2 PF13145.6 GBG49012.1 - 1 10.2 16.6 0.13 13.1 2.5 2.5 1 1 1 2 2 2 0 PPIC-type PPIASE domain REV PF00424.18 GBG49012.1 - 9.5 6.3 10.7 0.11 12.5 0.6 2.4 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Hep_59 PF07052.11 GBG49091.1 - 0.047 14.4 5.0 0.088 13.6 5.0 1.5 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 DUF2681 PF10883.8 GBG49091.1 - 0.052 13.9 4.9 0.11 12.9 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) V_ATPase_I PF01496.19 GBG49091.1 - 1.2 7.0 5.6 1.4 6.7 5.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.11 GBG49091.1 - 2.2 6.7 14.3 2.7 6.4 14.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Atrophin-1 PF03154.15 GBG49091.1 - 2.5 6.3 10.5 2.9 6.1 10.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF1682 PF07946.14 GBG49091.1 - 2.8 7.1 13.5 4.2 6.5 13.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Rrn6 PF10214.9 GBG49091.1 - 7.8 4.8 8.9 11 4.4 8.6 1.3 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RT_RNaseH PF17917.1 GBG49146.1 - 2e-17 63.4 0.0 3.3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG49146.1 - 5.3e-15 55.3 0.1 1.1e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG49146.1 - 1.7e-14 53.7 0.0 2.8e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG49146.1 - 2e-05 24.8 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG49146.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG49175.1 - 4.2e-07 30.5 0.6 1.1e-06 29.1 0.0 2.1 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG49175.1 - 0.00013 22.5 0.0 0.001 19.7 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG49175.1 - 0.0049 16.7 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG49175.1 - 0.013 15.8 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease FAM76 PF16046.5 GBG49175.1 - 6.6 6.0 7.3 10 5.3 7.3 1.2 1 0 0 1 1 1 0 FAM76 protein Borrelia_P83 PF05262.11 GBG49221.1 - 0.092 11.2 14.7 0.11 11.0 14.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2785 PF10978.8 GBG49221.1 - 1.1 9.0 7.3 0.11 12.3 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) RNA_pol_3_Rpc31 PF11705.8 GBG49221.1 - 6.1 7.0 17.6 0.093 13.0 7.8 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 HsdM_N PF12161.8 GBG49243.1 - 0.034 14.8 0.5 0.036 14.7 0.5 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain Swi6_N PF18530.1 GBG49243.1 - 0.1 12.7 0.2 0.14 12.3 0.2 1.2 1 0 0 1 1 1 0 Swi6 N-terminal domain HBS1_N PF08938.10 GBG49243.1 - 0.13 12.6 4.0 0.18 12.1 4.0 1.2 1 0 0 1 1 1 0 HBS1 N-terminus KTI12 PF08433.10 GBG49243.1 - 0.13 11.7 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF4618 PF15397.6 GBG49258.1 - 0.081 12.3 0.2 0.13 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 GBG49258.1 - 0.21 12.1 1.0 0.73 10.3 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 GBG49258.1 - 2.9 8.3 4.2 5.1 7.5 1.0 2.5 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ATG16 PF08614.11 GBG49258.1 - 9.8 6.3 11.8 16 5.7 0.5 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) NPR3 PF03666.13 GBG49331.1 - 4.4 6.0 21.5 4.8 5.8 21.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 GBG49331.1 - 4.6 7.2 16.1 5.7 6.9 16.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Rhabdo_ncap PF00945.18 GBG49331.1 - 6.9 5.4 6.6 3.1 6.6 4.7 1.3 1 1 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF4604 PF15377.6 GBG49331.1 - 8.1 6.8 24.5 11 6.4 24.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Prominin PF05478.11 GBG58600.1 - 0.13 10.2 3.4 0.2 9.6 3.4 1.2 1 0 0 1 1 1 0 Prominin ATG16 PF08614.11 GBG58600.1 - 0.27 11.4 25.4 0.025 14.8 18.7 2.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 GBG58600.1 - 0.31 11.1 10.4 0.25 11.4 7.3 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5100 PF17029.5 GBG58600.1 - 0.34 10.8 3.9 0.29 11.0 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5100) CREPT PF16566.5 GBG58600.1 - 2.5 8.3 13.7 0.41 10.8 6.6 2.8 1 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour BLOC1_2 PF10046.9 GBG58600.1 - 3 8.2 10.2 1.3 9.3 3.8 3.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LMBR1 PF04791.16 GBG58600.1 - 5.4 5.8 7.7 7.1 5.4 7.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Bacillus_HBL PF05791.11 GBG58600.1 - 6.1 6.6 9.3 0.7 9.7 2.6 2.5 2 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 GBG58600.1 - 10 6.3 11.0 4.5 7.4 6.3 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Calmodulin_bind PF07887.11 GBG58601.1 - 5.8e-77 258.9 0.0 7.9e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Calmodulin binding protein-like ParBc PF02195.18 GBG58602.1 - 8.5e-15 54.8 0.1 1.4e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 ParB-like nuclease domain ParBc PF02195.18 GBG58603.1 - 7.3e-15 55.0 0.1 1.3e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 ParB-like nuclease domain RVT_1 PF00078.27 GBG58604.1 - 3.7e-24 85.5 0.1 7e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58604.1 - 9.7e-23 80.1 0.0 1.9e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58604.1 - 1.8e-21 76.4 0.0 3.5e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58604.1 - 1.7e-13 50.4 0.1 5.3e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG58604.1 - 7.7e-05 23.3 0.0 0.00022 21.8 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58604.1 - 0.00011 22.7 0.0 0.0017 18.9 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG58604.1 - 0.00012 22.0 0.2 0.00043 20.2 0.2 2.1 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 GBG58604.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease LMBR1 PF04791.16 GBG58604.1 - 0.25 10.2 7.8 35 3.1 9.6 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Holin_BhlA PF10960.8 GBG58604.1 - 0.63 10.1 8.3 1.7 8.7 8.3 1.7 1 0 0 1 1 1 0 BhlA holin family Xpo1 PF08389.12 GBG58604.1 - 0.77 9.8 2.6 3 7.9 2.5 2.1 2 0 0 2 2 2 0 Exportin 1-like protein WD40_alt PF14077.6 GBG58604.1 - 2.1 8.3 5.2 3.2 7.7 0.2 3.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif RT_RNaseH PF17917.1 GBG58605.1 - 1.4e-23 83.2 0.0 2.2e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58605.1 - 8.9e-23 80.2 0.0 1.3e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58605.1 - 8.7e-21 73.8 0.1 1.7e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG58605.1 - 0.027 14.7 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Calmodulin_bind PF07887.11 GBG58606.1 - 2.4e-99 332.3 0.0 3.1e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 Calmodulin binding protein-like DUF655 PF04919.12 GBG58606.1 - 0.099 12.6 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Calmodulin_bind PF07887.11 GBG58607.1 - 2.3e-99 332.4 0.0 3e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 Calmodulin binding protein-like DUF659 PF04937.15 GBG58609.1 - 1.5e-32 112.5 0.0 2.3e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG58609.1 - 3.6e-05 23.5 0.3 7.2e-05 22.5 0.3 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nop14 PF04147.12 GBG58609.1 - 3.9 5.6 4.7 12 4.0 4.9 1.6 2 0 0 2 2 2 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG58611.1 - 7.2e-36 122.2 0.0 6.8e-35 119.1 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58611.1 - 3e-29 101.4 0.1 9.1e-29 99.8 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58611.1 - 3.2e-18 65.6 0.2 8.9e-18 64.2 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG58611.1 - 1.8e-17 63.6 0.0 3.5e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG58611.1 - 1.9e-16 60.3 0.1 7.2e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG58611.1 - 0.0043 17.0 0.9 0.011 15.6 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG58611.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG58611.1 - 0.054 13.7 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 GBG58611.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Cpta_toxin PF07254.12 GBG58612.1 - 0.37 10.8 3.5 8.1 6.4 1.0 2.3 2 0 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system Pox_F17 PF04767.12 GBG58612.1 - 1.3 9.6 0.0 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein TPPK_C PF12555.8 GBG58612.1 - 7.5 6.7 10.2 16 5.6 10.2 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DDE_Tnp_4 PF13359.6 GBG58613.1 - 7.1e-16 58.3 0.0 3e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG58613.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein RT_RNaseH PF17917.1 GBG58614.1 - 3.5e-21 75.5 0.0 7.6e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58614.1 - 6.8e-19 67.8 0.0 1.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG58614.1 - 2.1e-06 28.2 0.0 4.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG58614.1 - 8.4e-05 22.2 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG58614.1 - 0.00027 21.5 0.0 0.0007 20.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG58614.1 - 0.0067 16.2 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG58614.1 - 0.018 15.3 1.1 0.067 13.5 1.1 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein RVP PF00077.20 GBG58614.1 - 0.049 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1180 PF06679.12 GBG58614.1 - 0.8 10.1 3.3 33 4.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF659 PF04937.15 GBG58616.1 - 4.5e-34 117.5 0.0 8.2e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG58616.1 - 6.5e-05 22.6 0.1 0.00016 21.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG58616.1 - 0.032 14.8 0.0 0.065 13.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG58616.1 - 0.13 13.0 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease AbiH PF14253.6 GBG58617.1 - 0.17 11.8 6.1 0.42 10.4 6.1 1.8 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Integrase_H2C2 PF17921.1 GBG58618.1 - 2.5e-18 65.9 0.2 4.9e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG58618.1 - 7.8e-16 58.3 0.0 1.8e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG58618.1 - 0.0019 18.1 1.2 0.0052 16.7 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 GBG58618.1 - 0.007 16.6 0.0 0.024 14.8 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG58618.1 - 0.012 15.9 0.0 0.034 14.4 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG58618.1 - 0.47 10.6 4.8 1.3 9.2 4.8 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG58618.1 - 0.82 9.5 2.9 1 9.1 0.9 2.2 3 0 0 3 3 3 0 Zinc knuckle RT_RNaseH PF17917.1 GBG58619.1 - 6.3e-27 93.9 0.3 1.2e-26 93.0 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58619.1 - 8.1e-20 70.7 0.1 1.7e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58619.1 - 3.3e-18 65.5 0.0 7.3e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG58619.1 - 3.3e-17 62.8 0.0 8.8e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG58619.1 - 0.016 15.4 0.0 0.061 13.6 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger SANT_DAMP1_like PF16282.5 GBG58619.1 - 0.22 11.8 2.1 10 6.4 0.1 3.6 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 RVT_1 PF00078.27 GBG58620.1 - 8.3e-30 104.0 0.0 7.3e-14 51.8 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3223 PF11523.8 GBG58620.1 - 1.7e-05 25.5 0.0 1.7e-05 25.5 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3223) Retrotrans_gag PF03732.17 GBG58620.1 - 0.041 14.1 0.0 0.19 12.1 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein CHASE6_C PF17150.4 GBG58620.1 - 0.48 11.1 3.4 11 6.8 0.0 3.3 3 0 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain Asp_protease_2 PF13650.6 GBG58621.1 - 1.3e-06 29.0 0.1 2.8e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58621.1 - 0.00012 22.6 0.2 0.00021 21.8 0.2 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG58621.1 - 0.004 17.0 0.1 0.0061 16.3 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RNA_pol_Rpb1_2 PF00623.20 GBG58623.1 - 1.8e-36 125.9 0.1 2.5e-35 122.2 0.1 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 GBG58623.1 - 6.6e-22 78.2 0.0 9.2e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 GBG58623.1 - 2e-17 63.6 0.0 5.8e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GBG58623.1 - 1.9e-08 34.2 1.6 6.2e-08 32.6 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DUF5320 PF17253.2 GBG58623.1 - 0.3 12.2 3.8 0.93 10.6 0.7 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF883 PF05957.13 GBG58623.1 - 2.3 8.9 5.7 0.81 10.3 0.9 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Dimer_Tnp_hAT PF05699.14 GBG58624.1 - 0.00041 20.1 0.1 0.00084 19.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CDC27 PF09507.10 GBG58624.1 - 0.17 11.3 20.4 0.25 10.7 20.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4207 PF13904.6 GBG58624.1 - 0.56 9.9 12.1 0.081 12.6 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Nop14 PF04147.12 GBG58624.1 - 7.2 4.7 30.2 11 4.0 30.2 1.3 1 0 0 1 1 1 0 Nop14-like family DUF755 PF05501.11 GBG58624.1 - 9.3 6.6 12.7 17 5.7 12.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RVT_1 PF00078.27 GBG58625.1 - 1.9e-28 99.5 0.0 3.3e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpb1_1 PF04997.12 GBG58625.1 - 2.4e-11 43.5 0.0 4.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 DDE_Tnp_4 PF13359.6 GBG58625.1 - 0.0022 17.7 0.1 0.0078 15.9 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease MRP-S26 PF14943.6 GBG58626.1 - 0.017 15.1 2.9 0.017 15.1 2.9 2.8 2 1 0 2 2 2 0 Mitochondrial ribosome subunit S26 RVP_2 PF08284.11 GBG58627.1 - 9.3e-06 25.5 0.0 2.2e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG58627.1 - 0.0003 20.4 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG58627.1 - 0.00039 21.0 0.0 0.00081 20.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58627.1 - 0.019 15.5 0.1 0.36 11.4 0.0 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG58627.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) GDP_Man_Dehyd PF16363.5 GBG58627.1 - 2.1 7.6 4.0 1.6 8.1 2.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase UPF0242 PF06785.11 GBG58627.1 - 7.2 6.7 8.6 24 5.0 6.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF659 PF04937.15 GBG58628.1 - 3.2e-25 88.8 0.0 7.9e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2201_N PF13203.6 GBG58629.1 - 0.037 13.6 16.1 0.047 13.3 16.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain BUD22 PF09073.10 GBG58629.1 - 0.82 8.9 22.3 1 8.7 22.3 1.1 1 0 0 1 1 1 0 BUD22 RT_RNaseH_2 PF17919.1 GBG58631.1 - 3.1e-20 72.1 0.0 7.3e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58631.1 - 6.4e-16 58.6 0.0 1.5e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG58631.1 - 9.9e-05 22.8 0.0 0.00025 21.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG58631.1 - 0.01 16.4 0.0 0.023 15.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_4 PF14392.6 GBG58631.1 - 0.21 11.3 1.7 0.63 9.8 1.7 1.8 1 0 0 1 1 1 0 Zinc knuckle DpnD-PcfM PF14207.6 GBG58631.1 - 0.31 11.0 2.8 0.23 11.4 0.2 2.3 2 0 0 2 2 2 0 DpnD/PcfM-like protein RBM1CTR PF08081.11 GBG58631.1 - 4.9 7.3 10.3 14 5.8 0.8 3.9 3 0 0 3 3 3 0 RBM1CTR (NUC064) family CREPT PF16566.5 GBG58632.1 - 0.0057 16.8 4.0 0.0078 16.4 4.0 1.2 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour betaPIX_CC PF16523.5 GBG58632.1 - 0.11 12.3 4.6 0.19 11.6 4.6 1.4 1 0 0 1 1 1 0 betaPIX coiled coil adh_short PF00106.25 GBG58633.1 - 1.1e-39 135.9 0.1 1.6e-39 135.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG58633.1 - 9.9e-23 80.9 0.0 1.3e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GBG58633.1 - 0.00017 21.1 0.1 0.00025 20.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GBG58633.1 - 0.0013 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GBG58633.1 - 0.0014 18.6 0.1 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GBG58633.1 - 0.0029 16.8 0.1 0.0049 16.0 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 GBG58633.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 GBG58633.1 - 0.12 11.5 0.3 0.4 9.8 0.3 1.8 1 1 0 1 1 1 0 Male sterility protein Kinesin PF00225.23 GBG58634.1 - 5.1e-90 301.8 0.8 8.5e-77 258.3 0.7 2.2 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 GBG58634.1 - 9.5e-09 35.4 0.0 1.8e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 Microtubule binding Presenilin PF01080.17 GBG58635.1 - 0.52 9.0 13.4 0.56 8.9 13.4 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GBG58635.1 - 1.5 8.0 6.8 1.5 7.9 6.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF5427 PF10310.9 GBG58635.1 - 3.4 6.5 15.7 3.7 6.4 15.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FCP1_C PF09309.10 GBG58635.1 - 3.9 7.3 23.5 4.6 7.0 23.5 1.2 1 0 0 1 1 1 0 FCP1, C-terminal NPR3 PF03666.13 GBG58635.1 - 9.8 4.8 24.3 0.38 9.5 18.7 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 ANAPC9 PF12856.7 GBG58637.1 - 0.099 12.8 1.2 0.39 10.9 0.5 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 9 RVT_1 PF00078.27 GBG58638.1 - 3.1e-29 102.1 0.1 4e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58638.1 - 8e-17 61.1 0.0 1.9e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58638.1 - 4.1e-08 33.5 0.0 9.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58641.1 - 4.3e-33 114.7 0.0 8.7e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG58641.1 - 2.5e-07 30.5 0.0 4.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG58641.1 - 5.6e-06 26.9 0.0 1.3e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58641.1 - 0.00083 19.9 0.0 0.0028 18.2 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG58641.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) CcdA PF07362.12 GBG58642.1 - 2.2 8.8 5.2 31 5.1 0.3 3.8 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA RT_RNaseH PF17917.1 GBG58644.1 - 3.9e-25 88.2 0.0 1.2e-24 86.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58644.1 - 3.9e-22 78.2 0.0 7.8e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG58644.1 - 3.9e-14 52.9 0.0 2.3e-07 31.0 0.0 2.7 1 1 1 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG58644.1 - 1.9e-10 40.7 0.0 4.7e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG58644.1 - 6.9e-09 35.7 0.0 1.8e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain 2-oxoacid_dh PF00198.23 GBG58645.1 - 4.6e-63 212.8 0.1 6.5e-63 212.3 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GBG58645.1 - 7.2e-15 54.6 2.0 1.5e-14 53.6 2.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GBG58645.1 - 2.2e-13 50.3 0.2 7.4e-13 48.6 0.2 2.1 1 0 0 1 1 1 1 e3 binding domain GCV_H PF01597.19 GBG58645.1 - 0.14 12.1 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Peptidase_S9 PF00326.21 GBG58646.1 - 3e-37 128.2 0.0 5.5e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GBG58646.1 - 3.5e-11 43.3 0.5 1.9e-07 31.0 0.9 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG58646.1 - 4.3e-11 42.5 0.7 2.6e-07 30.2 0.2 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PD40 PF07676.12 GBG58646.1 - 3.1e-07 30.2 2.5 0.0019 18.1 0.1 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DLH PF01738.18 GBG58646.1 - 7.6e-07 28.9 0.0 6.7e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family COesterase PF00135.28 GBG58646.1 - 1.4e-05 24.2 0.0 2.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S15 PF02129.18 GBG58646.1 - 0.0015 18.2 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF2920 PF11144.8 GBG58646.1 - 0.0056 15.9 0.0 0.013 14.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) FSH1 PF03959.13 GBG58646.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 GBG58646.1 - 0.016 15.0 0.5 0.046 13.6 0.1 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 GBG58646.1 - 0.061 12.1 0.0 0.13 11.1 0.0 1.4 2 0 0 2 2 2 0 Serine carboxypeptidase S28 Esterase PF00756.20 GBG58646.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Hexapep PF00132.24 GBG58648.1 - 1.5e-12 46.7 7.7 0.00015 21.4 0.2 3.7 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GBG58648.1 - 1.5e-07 31.0 4.5 0.0051 16.5 0.0 3.6 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase RVT_1 PF00078.27 GBG58649.1 - 2.6e-29 102.3 1.1 4.7e-29 101.5 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG58649.1 - 2e-07 31.6 0.0 5.2e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58649.1 - 4e-06 27.3 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG58649.1 - 2.3e-05 24.2 0.0 4.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG58649.1 - 0.0025 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG58649.1 - 0.017 15.4 4.0 0.047 14.0 0.0 3.5 3 0 0 3 3 3 0 Retrotransposon gag protein SPARC_Ca_bdg PF10591.9 GBG58649.1 - 0.2 12.0 2.2 0.48 10.7 0.7 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region AIF-MLS PF14962.6 GBG58649.1 - 1.5 8.8 5.9 3.1 7.7 5.9 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Cellulase PF00150.18 GBG58652.1 - 6.7e-13 48.7 0.2 9.3e-13 48.2 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2095 PF09868.9 GBG58652.1 - 0.12 12.3 0.9 4.1 7.4 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2095) RT_RNaseH_2 PF17919.1 GBG58653.1 - 3.9e-29 100.6 0.0 8.1e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58653.1 - 3.3e-27 94.8 0.0 5.7e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58653.1 - 6.5e-14 52.0 0.1 9.3e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58655.1 - 3.3e-23 81.6 0.0 7.9e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58655.1 - 7.7e-21 74.4 0.0 1.7e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG58655.1 - 3.8e-11 43.2 0.0 1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG58655.1 - 2.2e-10 40.4 0.3 5.6e-10 39.1 0.3 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AC_N PF16214.5 GBG58655.1 - 0.71 8.9 2.5 1.4 8.0 2.5 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF659 PF04937.15 GBG58656.1 - 3.1e-32 111.6 0.5 7e-32 110.4 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DUF4484 PF14831.6 GBG58657.1 - 0.35 10.9 8.4 0.061 13.4 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) RVT_1 PF00078.27 GBG58658.1 - 1.2e-29 103.4 0.1 2.1e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58658.1 - 2.8e-24 85.1 0.0 7.4e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58658.1 - 1.7e-21 76.5 0.0 3.9e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG58658.1 - 2.3e-08 34.5 0.0 1.6e-07 31.8 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58658.1 - 2e-07 31.4 0.0 7.3e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG58658.1 - 1.4e-05 24.9 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG58658.1 - 0.00017 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG58658.1 - 0.0018 18.5 0.1 0.036 14.3 0.0 3.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG58659.1 - 2e-07 30.7 2.6 5.5e-07 29.4 2.6 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG58659.1 - 0.043 13.6 0.9 0.11 12.3 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Dynein_C PF18199.1 GBG58661.1 - 1.1e-105 353.3 0.0 1.9e-105 352.5 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 GBG58661.1 - 2.4e-91 304.8 0.6 2.4e-91 304.8 0.6 3.2 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 GBG58661.1 - 2.6e-60 202.9 0.0 4.6e-60 202.1 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GBG58661.1 - 7.4e-47 158.3 0.0 7.8e-44 148.6 0.0 2.6 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 GBG58661.1 - 2.5e-16 59.6 0.3 2.5e-16 59.6 0.3 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor MAGI_u5 PF16666.5 GBG58661.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI Baculo_PEP_C PF04513.12 GBG58661.1 - 0.82 9.7 7.5 0.24 11.4 0.7 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SDA1 PF05285.12 GBG58661.1 - 1.4 8.2 57.9 2.7 7.3 57.9 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG58661.1 - 4.7 5.3 57.8 8.1 4.5 57.8 1.3 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH PF17917.1 GBG58662.1 - 4.9e-15 55.7 1.5 1.1e-14 54.5 1.5 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58662.1 - 1.3e-09 38.0 0.3 4.5e-09 36.3 0.3 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG58662.1 - 1.4e-07 31.3 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG58662.1 - 0.00065 20.3 0.0 0.0035 18.0 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG58662.1 - 0.0031 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG58662.1 - 0.0034 17.9 0.1 0.015 15.8 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Spc29 PF17082.5 GBG58662.1 - 0.014 15.2 0.4 0.014 15.2 0.4 1.8 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF1664 PF07889.12 GBG58662.1 - 0.047 13.7 1.1 0.23 11.5 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Asp_protease PF09668.10 GBG58662.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF4806 PF16064.5 GBG58662.1 - 0.15 12.3 0.3 0.6 10.4 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4806) Adaptin_binding PF10199.9 GBG58662.1 - 1.6 9.4 8.3 3.4 8.3 1.9 2.8 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 AAA_6 PF12774.7 GBG58663.1 - 3.5e-119 397.6 0.6 1.3e-116 389.2 0.0 3.1 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 GBG58663.1 - 6e-105 350.3 0.0 1.1e-104 349.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 GBG58663.1 - 1.7e-77 259.0 0.2 7.3e-73 243.9 0.0 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region RVT_1 PF00078.27 GBG58663.1 - 4.2e-54 183.4 0.4 9.6e-30 103.7 0.1 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MT PF12777.7 GBG58663.1 - 8.6e-31 107.2 12.3 6.3e-28 97.8 4.4 2.4 2 0 0 2 2 2 2 Microtubule-binding stalk of dynein motor RT_RNaseH_2 PF17919.1 GBG58663.1 - 1.3e-28 99.0 0.0 7.2e-15 54.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Dynein_AAA_lid PF17852.1 GBG58663.1 - 2.2e-28 98.9 0.7 9e-28 96.9 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain RT_RNaseH PF17917.1 GBG58663.1 - 4e-28 97.8 0.0 1.2e-27 96.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AAA_lid_1 PF17857.1 GBG58663.1 - 1.3e-17 63.8 0.1 4.5e-17 62.1 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain Integrase_H2C2 PF17921.1 GBG58663.1 - 3.4e-13 49.5 0.0 3.4e-13 49.5 0.0 2.1 3 0 0 3 3 1 1 Integrase zinc binding domain AAA_5 PF07728.14 GBG58663.1 - 5.9e-12 45.8 0.0 2.4e-05 24.3 0.0 4.7 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA PF00004.29 GBG58663.1 - 6.4e-05 23.4 0.2 0.0042 17.5 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG58663.1 - 0.00019 21.8 1.7 0.26 11.7 0.0 4.7 4 0 0 4 4 4 1 AAA ATPase domain zf-H2C2 PF09337.10 GBG58663.1 - 0.00031 20.9 0.0 0.00097 19.3 0.0 1.9 2 0 0 2 2 1 1 H2C2 zinc finger AAA_22 PF13401.6 GBG58663.1 - 0.00081 19.7 2.9 2.7 8.3 0.0 5.0 5 0 0 5 5 5 1 AAA domain TsaE PF02367.17 GBG58663.1 - 0.014 15.4 0.4 0.75 9.8 0.1 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 GBG58663.1 - 0.045 13.6 0.1 0.18 11.7 0.1 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DHC_N2 PF08393.13 GBG58664.1 - 1.9e-69 234.7 3.5 3e-57 194.5 3.0 2.5 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 GBG58664.1 - 3.3e-19 69.0 0.1 3.3e-19 69.0 0.1 1.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region gag-asp_proteas PF13975.6 GBG58664.1 - 2.2e-08 34.6 0.0 5.8e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG58664.1 - 9.4e-08 32.6 0.0 3e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG58664.1 - 1.7e-05 24.6 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG58664.1 - 3e-05 23.8 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease AAA PF00004.29 GBG58664.1 - 0.024 15.1 0.1 0.058 13.8 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GBG58664.1 - 0.22 12.1 1.9 0.38 11.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain DHC_N2 PF08393.13 GBG58665.1 - 2.5e-19 69.7 2.3 2.5e-19 69.7 2.3 2.9 3 2 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 FlxA PF14282.6 GBG58665.1 - 0.023 14.7 0.2 0.023 14.7 0.2 4.0 4 1 0 4 4 4 0 FlxA-like protein Retrotrans_gag PF03732.17 GBG58665.1 - 0.055 13.7 14.4 0.14 12.5 0.7 5.0 5 0 0 5 5 5 0 Retrotransposon gag protein SNN_linker PF09050.10 GBG58666.1 - 0.72 9.7 0.1 0.72 9.7 0.1 2.9 3 0 0 3 3 3 0 Stannin unstructured linker RVT_1 PF00078.27 GBG58667.1 - 5.5e-30 104.5 0.0 9.2e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58667.1 - 1.6e-29 101.8 0.0 2.3e-16 59.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58667.1 - 2.9e-28 98.2 0.0 6.5e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG58667.1 - 3.3e-12 46.1 0.0 8.1e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG58667.1 - 2.2e-11 44.0 0.0 7.6e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG58668.1 - 4.3e-08 32.9 0.2 1.3e-07 31.4 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG58668.1 - 7.5e-07 29.7 0.0 2.4e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG58668.1 - 8.3e-07 28.9 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG58668.1 - 2.2e-06 28.1 0.0 7e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG58668.1 - 0.00011 21.9 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG58668.1 - 0.0023 17.9 0.0 0.0073 16.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PBP_GOBP PF01395.22 GBG58668.1 - 0.15 12.2 1.5 0.37 11.0 1.5 1.6 1 0 0 1 1 1 0 PBP/GOBP family RT_RNaseH_2 PF17919.1 GBG58669.1 - 1.9e-22 79.2 0.0 5.6e-22 77.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58669.1 - 6.4e-20 71.4 0.0 2.1e-19 69.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58669.1 - 1.1e-18 67.6 0.2 5e-18 65.4 0.2 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG58669.1 - 1.1e-15 57.4 1.5 3.3e-15 55.9 0.5 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain zf-C3HC4_3 PF13920.6 GBG58669.1 - 5.5e-08 32.6 8.3 5.5e-08 32.6 8.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG58669.1 - 3.6e-07 29.9 11.6 8.9e-07 28.6 11.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG58669.1 - 7e-06 25.8 11.6 1.7e-05 24.6 11.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG58669.1 - 7e-05 22.7 11.2 7e-05 22.7 11.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-H2C2 PF09337.10 GBG58669.1 - 0.00092 19.4 1.0 0.0046 17.2 0.1 2.6 2 0 0 2 2 2 1 H2C2 zinc finger zf-RING_2 PF13639.6 GBG58669.1 - 0.0025 18.1 10.6 0.0078 16.5 10.6 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GBG58669.1 - 0.0028 17.5 8.8 0.0028 17.5 8.8 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GBG58669.1 - 0.0059 16.6 9.8 0.017 15.2 9.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 GBG58669.1 - 0.0077 16.1 3.4 0.016 15.0 3.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein LepA_C PF06421.12 GBG58669.1 - 0.023 14.9 0.4 0.13 12.5 0.4 2.3 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus Chromo PF00385.24 GBG58669.1 - 0.03 14.2 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-rbx1 PF12678.7 GBG58669.1 - 0.057 13.7 6.1 0.18 12.1 6.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Glyco_hydro_15 PF00723.21 GBG58669.1 - 0.42 9.3 4.0 0.92 8.2 4.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 DZR PF12773.7 GBG58669.1 - 1 9.4 5.7 3.1 7.9 5.7 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.6 GBG58669.1 - 1.5 8.7 5.8 3.3 7.6 5.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GBG58669.1 - 3.7 7.8 8.9 8.9 6.6 8.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Retrotrans_gag PF03732.17 GBG58670.1 - 0.0048 17.1 0.1 0.023 14.9 0.1 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein Lipin_mid PF16876.5 GBG58670.1 - 0.049 13.8 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain RT_RNaseH PF17917.1 GBG58671.1 - 3.7e-25 88.2 0.0 6.6e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58671.1 - 7.8e-19 67.6 0.0 1.6e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58671.1 - 1.9e-17 63.1 0.1 3.3e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG58671.1 - 1.4e-15 57.5 0.0 2.5e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG58671.1 - 5.7e-05 23.2 0.0 0.00019 21.6 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG58671.1 - 0.098 12.4 0.0 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain STI1 PF17830.1 GBG58671.1 - 0.16 12.0 0.2 0.78 9.7 0.1 2.1 2 0 0 2 2 2 0 STI1 domain RT_RNaseH_2 PF17919.1 GBG58672.1 - 3.8e-32 110.3 0.1 1.7e-31 108.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58672.1 - 4.7e-32 111.3 0.1 8.4e-32 110.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG58672.1 - 2.8e-19 69.4 0.0 7.1e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58672.1 - 9.9e-18 64.0 0.1 2.5e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG58672.1 - 1.1e-14 54.7 0.0 3.7e-14 52.9 0.0 1.9 2 0 0 2 2 1 1 Integrase core domain zf-CCHC PF00098.23 GBG58672.1 - 4.8e-07 29.6 3.7 1.5e-06 28.0 3.7 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-GRF PF06839.12 GBG58672.1 - 2.1e-05 24.5 0.4 5e-05 23.3 0.4 1.6 1 0 0 1 1 1 1 GRF zinc finger gag-asp_proteas PF13975.6 GBG58672.1 - 0.00021 21.8 0.0 0.0011 19.5 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1564 PF07600.11 GBG58672.1 - 0.0014 18.4 0.1 0.012 15.3 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG58672.1 - 0.0069 16.6 0.0 0.025 14.8 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG58672.1 - 0.059 14.0 0.0 0.21 12.3 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG58672.1 - 0.078 12.8 4.3 0.034 14.0 1.7 1.8 2 0 0 2 2 2 0 Zinc knuckle HepII_C PF18675.1 GBG58672.1 - 0.13 12.4 0.0 29 4.9 0.0 2.7 2 0 0 2 2 2 0 Heparinase II C-terminal domain BAF250_C PF12031.8 GBG58672.1 - 0.15 11.3 0.1 0.36 10.1 0.1 1.6 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa zf-CCHC_5 PF14787.6 GBG58672.1 - 0.16 11.7 1.0 0.37 10.5 1.0 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 GBG58672.1 - 0.59 10.1 2.2 0.62 10.1 0.5 2.0 2 0 0 2 2 2 0 Zinc knuckle Topoisom_bac PF01131.20 GBG58673.1 - 1.5e-31 109.9 0.0 1.9e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-C4_Topoisom PF01396.19 GBG58673.1 - 1.3e-09 37.7 0.3 1.3e-09 37.7 0.3 2.0 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Topoisom_bac PF01131.20 GBG58674.1 - 2.5e-26 92.6 0.0 1.1e-18 67.5 0.0 2.7 2 0 0 2 2 2 2 DNA topoisomerase RT_RNaseH PF17917.1 GBG58674.1 - 2e-13 50.5 0.6 2.4e-12 47.1 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Toprim PF01751.22 GBG58674.1 - 2e-08 34.4 0.0 4.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Toprim domain RT_RNaseH_2 PF17919.1 GBG58674.1 - 2.5e-06 27.4 0.0 1.3e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG58674.1 - 1e-05 26.0 0.0 2.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG58674.1 - 1.2e-05 25.1 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG58674.1 - 9.3e-05 22.9 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG58674.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG58674.1 - 0.00084 19.1 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG58675.1 - 8.6e-21 74.5 0.3 1.3e-20 73.9 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58675.1 - 2.1e-20 72.6 0.0 4.2e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58675.1 - 1.3e-09 38.2 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDH1_2_SANT_HL1 PF18375.1 GBG58675.1 - 0.11 13.2 0.0 0.45 11.2 0.0 1.9 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 CHASE6_C PF17150.4 GBG58675.1 - 0.15 12.7 0.1 2 9.1 0.1 2.2 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain RVT_1 PF00078.27 GBG58677.1 - 9.6e-19 67.8 0.0 1.6e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG58677.1 - 2.2e-11 43.7 1.6 3.7e-11 43.0 1.6 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG58677.1 - 0.0009 19.1 0.0 0.0038 17.1 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Ubiquitin_4 PF18036.1 GBG58677.1 - 0.027 14.5 0.2 0.059 13.4 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Glyco_transf_34 PF05637.12 GBG58678.1 - 7.6e-28 97.8 0.0 3.4e-26 92.4 0.0 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 GBG58678.1 - 3.6e-07 30.0 0.0 7.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Glycos_transf_2 PF00535.26 GBG58678.1 - 0.043 13.6 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Nucleotid_trans PF03407.16 GBG58678.1 - 0.077 13.0 0.2 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_tranf_2_4 PF13704.6 GBG58678.1 - 0.11 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF4946 PF16304.5 GBG58681.1 - 0.062 13.0 0.6 0.14 11.9 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4946) Ferlin_C PF16165.5 GBG58681.1 - 6.4 6.7 7.8 12 5.8 7.8 1.5 1 0 0 1 1 1 0 Ferlin C-terminus CCDC66 PF15236.6 GBG58681.1 - 8.1 6.3 23.8 1.3 8.9 16.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 CRAL_TRIO PF00650.20 GBG58683.1 - 1.8e-30 105.8 0.0 2.4e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GBG58683.1 - 0.0062 16.7 0.0 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GBG58683.1 - 0.013 15.6 0.4 0.03 14.5 0.1 1.8 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain Peptidase_M23 PF01551.22 GBG58683.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 FPP PF05911.11 GBG58684.1 - 0.01 14.1 8.2 0.013 13.7 8.2 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TMF_TATA_bd PF12325.8 GBG58684.1 - 0.09 13.0 19.7 1.4 9.1 3.0 3.1 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 GBG58684.1 - 0.12 11.2 15.2 0.46 9.3 5.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein FlxA PF14282.6 GBG58684.1 - 0.2 11.7 6.5 1.4 8.9 1.3 2.5 2 1 0 2 2 2 0 FlxA-like protein DASH_Dad2 PF08654.10 GBG58684.1 - 0.5 10.8 5.7 5.7 7.4 0.1 3.3 1 1 1 2 2 2 0 DASH complex subunit Dad2 DUF4407 PF14362.6 GBG58684.1 - 0.58 9.5 10.7 0.27 10.5 8.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YabA PF06156.13 GBG58684.1 - 2 9.1 10.1 10 6.8 1.4 2.8 2 1 0 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 GBG58684.1 - 3 7.9 18.1 0.8 9.8 7.1 2.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 GBG58684.1 - 3.1 7.6 18.6 0.099 12.4 1.5 3.9 2 2 2 4 4 4 0 Septum formation initiator DUF4140 PF13600.6 GBG58684.1 - 6.5 7.3 14.7 5.5 7.5 4.9 3.1 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1690 PF07956.11 GBG58684.1 - 9.2 6.7 13.3 0.17 12.3 2.0 2.3 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) SOCS_box PF07525.16 GBG58685.1 - 0.018 15.4 0.3 0.059 13.7 0.3 1.9 1 0 0 1 1 1 0 SOCS box Integrase_H2C2 PF17921.1 GBG58686.1 - 3.6e-18 65.4 0.0 7.3e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG58686.1 - 2.3e-15 56.8 0.1 5.1e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG58686.1 - 0.00017 21.8 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG58686.1 - 0.00063 19.5 0.0 0.0019 17.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Chromo PF00385.24 GBG58686.1 - 0.0086 16.0 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG58687.1 - 4e-53 177.6 0.0 4.3e-25 87.7 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58687.1 - 7.8e-45 151.5 0.0 7.2e-21 74.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58687.1 - 1.3e-08 34.7 0.0 2.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YL1 PF05764.13 GBG58687.1 - 0.61 10.2 11.2 3.7 7.6 0.9 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Glyco_hydro_64 PF16483.5 GBG58688.1 - 2.4e-90 303.5 0.0 3.2e-90 303.1 0.0 1.2 1 0 0 1 1 1 1 Beta-1,3-glucanase CBM_6 PF03422.15 GBG58688.1 - 2.3e-28 99.0 0.0 4.8e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GBG58688.1 - 2.5e-07 30.8 0.0 5.9e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 DUF5010 C-terminal domain DUF261 PF03196.13 GBG58688.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF261 DUF913 PF06025.12 GBG58690.1 - 2.8 6.8 29.2 0.12 11.3 7.2 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Exo_endo_phos_2 PF14529.6 GBG58691.1 - 0.00021 21.1 0.0 0.00066 19.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GBG58691.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 GBG58691.1 - 0.04 14.0 1.5 0.073 13.2 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG58692.1 - 0.00061 19.4 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_1 PF00036.32 GBG58692.1 - 0.0024 17.3 0.2 0.0076 15.7 0.2 1.8 1 0 0 1 1 1 1 EF hand zf-CCHC_3 PF13917.6 GBG58692.1 - 0.014 15.4 1.0 0.027 14.4 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle CC2-LZ PF16516.5 GBG58692.1 - 0.035 14.5 3.9 0.11 12.9 3.9 1.8 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1666 PF07891.12 GBG58692.1 - 0.045 13.4 0.6 0.13 11.9 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) EF-hand_7 PF13499.6 GBG58692.1 - 0.054 14.0 0.4 0.23 12.0 0.0 2.3 2 0 0 2 2 1 0 EF-hand domain pair GrpE PF01025.19 GBG58692.1 - 0.11 12.2 3.8 0.25 11.0 3.8 1.7 1 0 0 1 1 1 0 GrpE zf-CCHC_4 PF14392.6 GBG58692.1 - 0.17 11.7 0.8 0.33 10.7 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2570 PF10828.8 GBG58692.1 - 0.49 10.2 3.3 1.5 8.6 3.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) zf-CCHC PF00098.23 GBG58692.1 - 1.4 9.1 4.9 2.2 8.5 4.9 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4407 PF14362.6 GBG58692.1 - 1.8 7.9 6.8 0.19 11.0 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 GBG58692.1 - 9 6.1 12.9 1.7 8.5 8.6 2.0 2 0 0 2 2 1 0 Septum formation initiator Phage_fiber PF03335.13 GBG58693.1 - 0.065 13.4 1.2 0.21 11.8 1.2 1.9 1 0 0 1 1 1 0 Phage tail fibre repeat Myb_DNA-bind_4 PF13837.6 GBG58694.1 - 1.8e-06 28.2 1.0 3.3e-06 27.4 1.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG58696.1 - 9.2e-60 198.9 0.0 1e-30 105.7 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58696.1 - 1.9e-56 188.8 0.1 2.5e-28 98.4 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58696.1 - 3.9e-50 170.4 0.3 8.5e-30 103.9 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG58696.1 - 0.00057 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG58696.1 - 0.00064 20.2 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG58696.1 - 0.0024 18.4 0.0 0.0056 17.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG58696.1 - 0.0053 16.5 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_3 PF13917.6 GBG58696.1 - 0.12 12.4 11.0 0.02 14.9 1.1 3.1 4 0 0 4 4 4 0 Zinc knuckle RCC1 PF00415.18 GBG58697.1 - 3.2e-64 213.4 33.2 7.4e-15 55.3 0.1 8.5 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.22 GBG58697.1 - 4.9e-39 132.0 0.0 1.1e-09 38.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RCC1_2 PF13540.6 GBG58697.1 - 8.3e-35 117.9 37.0 4e-08 32.8 1.3 6.8 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Sec23_trunk PF04811.15 GBG58697.1 - 1.1e-25 90.6 0.0 1.7e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GBG58697.1 - 9.6e-19 67.1 0.0 2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain DUF563 PF04577.14 GBG58697.1 - 4e-14 53.3 0.1 1.1e-13 51.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) zf-Sec23_Sec24 PF04810.15 GBG58697.1 - 5e-05 23.3 5.6 0.00013 22.0 5.6 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 GBG58697.1 - 0.0049 17.6 0.9 0.024 15.4 0.0 2.5 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Limkain-b1 PF11608.8 GBG58697.1 - 0.042 13.9 2.7 11 6.2 0.1 4.1 4 0 0 4 4 4 0 Limkain b1 Nup35_RRM_2 PF14605.6 GBG58697.1 - 0.055 13.5 0.1 1.7 8.7 0.0 3.1 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif DUF2053 PF09767.9 GBG58698.1 - 3.1e-55 186.7 1.8 3.1e-55 186.7 1.8 1.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2053) Na_trans_assoc PF06512.13 GBG58699.1 - 0.0027 18.0 4.6 0.004 17.5 4.6 1.5 1 1 0 1 1 1 1 Sodium ion transport-associated Nop14 PF04147.12 GBG58699.1 - 0.57 8.3 20.9 0.66 8.1 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG58699.1 - 1.8 8.2 19.6 2.6 7.7 19.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG58699.1 - 2.5 6.3 16.2 3.2 5.9 16.2 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG58699.1 - 3.5 7.0 21.7 3.9 6.8 21.7 1.1 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 GBG58699.1 - 5.2 7.0 39.9 7.6 6.5 39.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) UPF0113_N PF17833.1 GBG58700.1 - 3.4e-26 91.6 0.0 4.9e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 GBG58700.1 - 2.7e-24 85.2 0.0 5.2e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain TPR_1 PF00515.28 GBG58701.1 - 5.1e-36 121.0 12.8 2.2e-08 33.6 1.1 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 GBG58701.1 - 1.6e-26 90.2 30.2 4.2e-06 26.5 1.7 11.3 11 0 0 11 11 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG58701.1 - 6.7e-23 80.7 32.0 2.1e-17 63.1 2.6 5.8 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GBG58701.1 - 5.9e-20 71.6 26.4 1.5e-08 35.2 0.1 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 GBG58701.1 - 7.1e-19 67.2 18.2 3.6e-06 26.6 0.3 8.6 4 2 5 9 9 9 5 TPR repeat TPR_8 PF13181.6 GBG58701.1 - 1.6e-17 62.2 14.0 0.097 12.9 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 GBG58701.1 - 8e-16 58.1 29.4 0.00025 21.3 2.2 8.2 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 GBG58701.1 - 2.1e-14 53.8 19.8 5e-06 26.9 0.8 7.7 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 GBG58701.1 - 6.9e-11 41.7 17.3 0.00088 19.5 0.4 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG58701.1 - 3.8e-08 33.5 26.4 0.18 12.7 0.3 8.6 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 GBG58701.1 - 1.5e-07 31.5 12.8 0.0051 16.9 0.1 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 GBG58701.1 - 3.4e-07 29.8 12.6 0.029 13.6 1.1 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GBG58701.1 - 4.3e-06 26.4 10.9 0.084 12.9 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG58701.1 - 0.0012 19.3 10.2 1.4 9.7 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 GBG58701.1 - 0.0036 17.0 3.5 0.006 16.3 0.6 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain ChAPs PF09295.10 GBG58701.1 - 0.06 12.3 0.1 6.6 5.6 0.0 2.9 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 GBG58701.1 - 0.095 13.0 0.6 0.41 11.0 0.4 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat Glyco_hydro_43 PF04616.14 GBG58702.1 - 9.5e-23 80.9 0.9 9.5e-23 80.9 0.9 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 BUD22 PF09073.10 GBG58702.1 - 0.002 17.5 47.5 0.0035 16.7 47.5 1.3 1 0 0 1 1 1 1 BUD22 TRP PF06011.12 GBG58702.1 - 0.46 9.2 0.0 0.46 9.2 0.0 1.4 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Membralin PF09746.9 GBG58702.1 - 0.62 9.0 12.8 1.1 8.2 12.8 1.3 1 0 0 1 1 1 0 Tumour-associated protein CENP-B_dimeris PF09026.10 GBG58702.1 - 1.1 9.6 24.4 0.43 11.0 12.0 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 GBG58702.1 - 2.3 7.5 33.3 4.6 6.5 12.9 2.5 2 0 0 2 2 2 0 NOA36 protein BSP_II PF05432.11 GBG58702.1 - 3.6 7.2 41.4 1.1 8.8 2.5 2.8 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) DUF3169 PF11368.8 GBG58702.1 - 3.6 7.0 6.8 29 4.1 7.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF4148 PF13663.6 GBG58703.1 - 1.6 8.9 3.6 0.45 10.7 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Integrase_H2C2 PF17921.1 GBG58704.1 - 6.3e-12 45.4 0.1 1.2e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG58704.1 - 4.7e-07 30.3 0.0 9.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG58704.1 - 4.5e-06 26.9 0.0 8.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG58704.1 - 4.1e-05 24.1 0.0 0.00011 22.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG58704.1 - 0.0084 15.9 0.2 0.048 13.5 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG58704.1 - 0.0099 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG58704.1 - 0.099 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger CEP209_CC5 PF16574.5 GBG58705.1 - 0.0029 17.8 5.8 0.0029 17.8 5.8 3.9 3 1 1 4 4 4 1 Coiled-coil region of centrosome protein CE290 Pilus_CpaD PF09476.10 GBG58705.1 - 0.0087 15.8 1.3 0.92 9.2 0.0 2.5 2 1 0 2 2 2 2 Pilus biogenesis CpaD protein (pilus_cpaD) YvrJ PF12841.7 GBG58705.1 - 0.17 11.4 0.2 0.79 9.3 0.0 2.3 2 0 0 2 2 2 0 YvrJ protein family Steroid_dh PF02544.16 GBG58706.1 - 2.7e-26 92.3 1.7 5.1e-26 91.5 1.7 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Retrotrans_gag PF03732.17 GBG58707.1 - 0.034 14.4 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG58708.1 - 2.1e-34 119.0 0.1 3.5e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58708.1 - 6.7e-31 106.3 0.0 2e-30 104.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58708.1 - 5.1e-29 100.6 0.0 1.1e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58708.1 - 0.00056 20.0 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG58708.1 - 0.056 13.1 0.0 0.056 13.1 0.0 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase CLU PF13236.6 GBG58709.1 - 3.3e-83 278.9 0.0 2.7e-82 275.9 0.0 2.2 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GBG58709.1 - 1.5e-47 161.9 0.0 4.4e-47 160.4 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 GBG58709.1 - 2.2e-26 92.0 7.0 9.1e-11 41.9 0.4 4.2 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GBG58709.1 - 1.2e-19 69.5 8.9 0.00017 21.4 0.2 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.6 GBG58709.1 - 1.6e-15 57.2 0.0 3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.17 GBG58709.1 - 0.00041 20.2 8.0 2.3 8.5 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG58709.1 - 0.008 16.0 5.5 0.8 9.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.12 GBG58709.1 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_8 PF13181.6 GBG58709.1 - 0.15 12.3 1.7 30 5.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Chrome_Resist PF09828.9 GBG58709.1 - 0.9 10.0 3.3 0.52 10.8 0.2 2.1 2 0 0 2 2 2 0 Chromate resistance exported protein LCE6A PF15858.5 GBG58709.1 - 8.3 7.2 17.0 2.9 8.7 6.2 3.4 2 0 0 2 2 2 0 Late cornified envelope protein 6A family RPA43_OB PF17875.1 GBG58710.1 - 9.1 6.9 8.8 1 10.0 3.7 2.0 1 1 1 2 2 2 0 RPA43 OB domain in RNA Pol I zf-CCHC PF00098.23 GBG58713.1 - 2.4e-07 30.5 2.6 6.3e-07 29.2 2.6 1.7 1 0 0 1 1 1 1 Zinc knuckle NARP1 PF12569.8 GBG58713.1 - 4 6.2 8.9 5.2 5.8 8.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF659 PF04937.15 GBG58714.1 - 9.6e-35 119.7 0.1 1.5e-34 119.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG58716.1 - 8.4e-08 32.7 0.0 2.4e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG58716.1 - 2.4e-06 28.1 0.0 1.5e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG58716.1 - 0.0017 18.6 0.0 0.0053 17.0 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG58716.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease BBL5 PF07289.11 GBG58716.1 - 0.088 11.8 0.0 14 4.6 0.0 2.3 2 0 0 2 2 2 0 Bardet-Biedl syndrome 5 protein DDE_Tnp_4 PF13359.6 GBG58717.1 - 3.5e-16 59.3 0.3 2.1e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG58717.1 - 1.1e-08 35.0 0.1 2.5e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein DUF5420 PF17457.2 GBG58718.1 - 0.017 15.0 0.3 0.029 14.3 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5420) Myb_DNA-bind_4 PF13837.6 GBG58718.1 - 0.27 11.6 3.0 1.9 8.9 1.2 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain CENP-B_dimeris PF09026.10 GBG58719.1 - 0.017 15.5 6.1 0.021 15.2 4.9 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Radial_spoke PF04712.12 GBG58719.1 - 0.38 9.6 7.7 0.54 9.1 7.7 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4637 PF15470.6 GBG58719.1 - 0.47 10.2 4.4 1.1 8.9 4.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RT_RNaseH_2 PF17919.1 GBG58720.1 - 4.9e-25 87.5 0.0 8.3e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58720.1 - 1.6e-22 79.7 0.0 3.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58720.1 - 2.7e-09 36.9 0.0 4.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CRT10 PF08728.10 GBG58720.1 - 0.19 9.9 0.1 0.25 9.4 0.1 1.1 1 0 0 1 1 1 0 CRT10 CDC45 PF02724.14 GBG58720.1 - 1.5 7.0 10.8 2.1 6.5 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG58721.1 - 1.3e-11 44.5 0.1 2e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Apc13p PF05839.11 GBG58721.1 - 0.35 11.1 9.2 1.1 9.5 9.2 1.8 1 0 0 1 1 1 0 Apc13p protein Na_trans_assoc PF06512.13 GBG58721.1 - 0.43 10.8 10.5 0.6 10.4 10.5 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated VIR_N PF15912.5 GBG58721.1 - 1.2 8.7 8.2 66 3.0 11.3 2.0 2 0 0 2 2 2 0 Virilizer, N-terminal UBX PF00789.20 GBG58722.1 - 8.2e-15 54.8 0.0 1.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain FSA_C PF10479.9 GBG58722.1 - 0.43 8.7 2.6 0.68 8.0 2.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF659 PF04937.15 GBG58723.1 - 1.2e-32 112.9 0.0 1.8e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG58723.1 - 3.1e-09 36.5 0.1 6.6e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG58723.1 - 0.064 13.1 4.4 0.22 11.5 4.4 2.0 1 0 0 1 1 1 0 AT hook motif Ribosomal_60s PF00428.19 GBG58724.1 - 0.0015 19.1 8.4 0.0015 19.1 8.4 2.4 3 0 0 3 3 2 2 60s Acidic ribosomal protein DNA_pol_phi PF04931.13 GBG58724.1 - 0.015 13.4 16.8 0.021 13.0 16.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 GBG58724.1 - 0.046 12.2 14.2 0.053 12.0 14.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Calcipressin PF04847.12 GBG58724.1 - 0.11 12.2 0.6 0.19 11.5 0.6 1.5 1 1 0 1 1 1 0 Calcipressin SDA1 PF05285.12 GBG58724.1 - 0.15 11.5 21.2 0.16 11.4 21.2 1.1 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 GBG58724.1 - 0.17 10.9 17.4 0.21 10.6 17.4 1.2 1 0 0 1 1 1 0 Paf1 CDC27 PF09507.10 GBG58724.1 - 0.2 11.0 9.6 0.2 11.0 9.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BUD22 PF09073.10 GBG58724.1 - 0.26 10.6 14.6 0.29 10.4 14.6 1.2 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 GBG58724.1 - 2.7 7.7 7.0 3.8 7.3 7.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SspB PF04386.13 GBG58724.1 - 3.4 7.5 5.2 4.9 7.0 5.2 1.3 1 0 0 1 1 1 0 Stringent starvation protein B Merozoite_SPAM PF07133.11 GBG58724.1 - 4.1 7.3 26.3 1.6 8.7 11.0 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) LRR_6 PF13516.6 GBG58725.1 - 1.6e-08 33.9 6.2 0.3 11.2 0.0 8.2 9 0 0 9 9 9 2 Leucine Rich repeat F-box-like PF12937.7 GBG58725.1 - 2e-07 30.8 0.3 2e-07 30.8 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GBG58725.1 - 0.00016 21.4 1.5 0.00078 19.3 0.2 2.6 2 0 0 2 2 2 1 F-box domain PRD PF00874.20 GBG58726.1 - 0.2 12.0 0.1 0.36 11.1 0.1 1.3 1 0 0 1 1 1 0 PRD domain BUD22 PF09073.10 GBG58728.1 - 0.1 11.9 10.8 0.092 12.1 10.8 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG58728.1 - 0.31 9.8 0.5 0.24 10.1 0.5 1.0 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 GBG58728.1 - 0.59 9.6 5.0 0.61 9.5 5.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4604 PF15377.6 GBG58728.1 - 1.6 9.1 18.0 2.1 8.8 18.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) CDC27 PF09507.10 GBG58728.1 - 3.6 6.9 12.4 4 6.7 12.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 GBG58728.1 - 7 6.0 22.1 7.8 5.8 22.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG58728.1 - 7.8 4.7 16.7 8.4 4.5 16.7 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 GBG58728.1 - 8.4 6.8 11.0 18 5.8 11.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RT_RNaseH_2 PF17919.1 GBG58729.1 - 3.4e-61 203.5 0.0 2.6e-29 101.2 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58729.1 - 1e-59 199.3 0.0 4.6e-29 100.8 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58729.1 - 4.7e-32 111.3 0.1 1.1e-31 110.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG58729.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DRY_EERY PF09750.9 GBG58729.1 - 0.57 10.5 0.0 0.57 10.5 0.0 3.3 4 0 0 4 4 4 0 Alternative splicing regulator zf-RING_2 PF13639.6 GBG58730.1 - 3.4e-09 36.9 8.1 6.6e-09 36.0 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG58730.1 - 1.2e-06 28.3 6.7 2e-06 27.5 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG58730.1 - 5.2e-06 26.2 7.0 8.9e-06 25.5 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG58730.1 - 1.5e-05 24.8 5.4 2.7e-05 24.0 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG58730.1 - 0.00033 20.6 7.0 0.00079 19.4 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GBG58730.1 - 0.0018 18.1 6.1 0.0032 17.3 6.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GBG58730.1 - 0.0019 18.3 5.7 0.0046 17.1 5.7 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 GBG58730.1 - 0.002 17.8 5.4 0.0051 16.5 5.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_6 PF14835.6 GBG58730.1 - 0.13 12.1 5.4 0.056 13.3 2.3 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GBG58730.1 - 0.14 12.5 9.2 0.58 10.5 9.2 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Baculo_RING PF05883.11 GBG58730.1 - 0.21 11.6 0.4 0.42 10.6 0.4 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-ANAPC11 PF12861.7 GBG58730.1 - 1 9.5 7.5 2.3 8.3 6.2 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GBG58730.1 - 1.3 8.7 6.2 2.6 7.8 6.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 GBG58730.1 - 1.5 9.0 4.5 2.9 8.0 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 GBG58730.1 - 4.4 7.2 8.3 11 6.0 8.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 GBG58731.1 - 3.4e-09 36.9 8.1 6.6e-09 36.0 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG58731.1 - 1.2e-06 28.3 6.7 2e-06 27.5 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG58731.1 - 5.2e-06 26.2 7.0 8.9e-06 25.5 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG58731.1 - 1.5e-05 24.8 5.4 2.7e-05 24.0 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG58731.1 - 0.00033 20.6 7.0 0.00079 19.4 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GBG58731.1 - 0.0018 18.1 6.1 0.0031 17.3 6.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GBG58731.1 - 0.0019 18.3 5.7 0.0046 17.1 5.7 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 GBG58731.1 - 0.002 17.8 5.4 0.005 16.5 5.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_6 PF14835.6 GBG58731.1 - 0.13 12.1 5.4 0.056 13.3 2.3 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GBG58731.1 - 0.14 12.5 9.2 0.58 10.5 9.2 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Baculo_RING PF05883.11 GBG58731.1 - 0.21 11.6 0.4 0.42 10.6 0.4 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-ANAPC11 PF12861.7 GBG58731.1 - 1 9.5 7.5 2.3 8.3 6.2 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GBG58731.1 - 1.3 8.7 6.2 2.6 7.8 6.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 GBG58731.1 - 1.5 9.0 4.5 2.9 8.0 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 GBG58731.1 - 4.3 7.2 8.3 10 6.0 8.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RVT_1 PF00078.27 GBG58732.1 - 1.8e-23 83.2 0.0 3e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG58732.1 - 1.7e-19 69.7 0.4 4.9e-19 68.2 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG58732.1 - 1.6e-08 34.7 0.5 1e-07 32.1 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain Asp_protease_2 PF13650.6 GBG58732.1 - 1.7e-07 31.8 0.0 3.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58732.1 - 8.9e-07 29.4 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG58732.1 - 4.7e-06 26.4 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG58732.1 - 0.0002 21.4 0.0 0.00084 19.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG58732.1 - 0.0005 19.8 0.0 0.00087 19.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG58732.1 - 0.0067 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MFS_2 PF13347.6 GBG58733.1 - 2.3e-05 23.2 0.8 4.2e-05 22.3 0.8 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 GBG58733.1 - 0.00013 21.1 2.8 0.006 15.5 2.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily E7 PF00527.18 GBG58733.1 - 0.067 13.4 0.2 0.21 11.8 0.2 1.8 1 0 0 1 1 1 0 E7 protein, Early protein DUF659 PF04937.15 GBG58734.1 - 3.6e-17 62.6 0.0 6.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) YbgT_YccB PF08173.11 GBG58735.1 - 0.29 11.3 2.8 0.46 10.7 0.0 2.6 3 0 0 3 3 3 0 Membrane bound YbgT-like protein DUF3138 PF11336.8 GBG58736.1 - 0.19 10.3 0.9 0.3 9.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RT_RNaseH PF17917.1 GBG58737.1 - 2e-23 82.7 0.0 4e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58737.1 - 2.5e-22 78.8 0.0 4.8e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase UPF0547 PF10571.9 GBG58737.1 - 1.3e-05 25.1 0.9 3e-05 24.0 0.9 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 GBG58737.1 - 0.00063 19.1 0.8 0.00063 19.1 0.8 1.8 2 0 0 2 2 2 1 zinc-ribbon domain Topo_Zn_Ribbon PF08272.11 GBG58737.1 - 0.038 13.6 0.3 0.093 12.4 0.3 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DZR PF12773.7 GBG58737.1 - 0.57 10.2 2.6 0.61 10.2 0.4 1.7 1 1 1 2 2 2 0 Double zinc ribbon DUF659 PF04937.15 GBG58738.1 - 4.8e-31 107.7 0.1 7.7e-31 107.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG58738.1 - 1.1e-08 34.7 0.1 2.6e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region VASt PF16016.5 GBG58738.1 - 0.061 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain PHD PF00628.29 GBG58739.1 - 9.5e-08 31.8 5.9 9.5e-08 31.8 5.9 3.1 3 0 0 3 3 3 1 PHD-finger UPF0547 PF10571.9 GBG58739.1 - 0.00031 20.7 2.3 0.00031 20.7 2.3 2.9 3 0 0 3 3 3 1 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 GBG58739.1 - 0.0006 19.1 1.2 0.0006 19.1 1.2 2.9 3 0 0 3 3 3 1 zinc-ribbon domain PHD_2 PF13831.6 GBG58739.1 - 0.0015 18.0 2.7 0.0015 18.0 2.7 2.6 3 0 0 3 3 3 1 PHD-finger zinc_ribbon_15 PF17032.5 GBG58739.1 - 1.3 9.8 6.3 0.15 12.8 0.8 2.2 2 0 0 2 2 2 0 zinc-ribbon family Asp_protease_2 PF13650.6 GBG58740.1 - 0.0082 16.8 0.1 0.017 15.7 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG58740.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase_Tyr PF07714.17 GBG58741.1 - 7.9e-41 140.0 0.0 1.4e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG58741.1 - 1e-34 120.1 0.0 3.8e-24 85.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Cyt-b5 PF00173.28 GBG58741.1 - 5.4e-18 64.9 0.1 1e-17 64.0 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC1 PF03109.16 GBG58741.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 GBG58741.1 - 0.14 10.9 0.3 0.26 10.0 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase RVT_1 PF00078.27 GBG58742.1 - 1.3e-12 47.7 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58742.1 - 1.9e-06 27.9 0.1 3.9e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PIF1 PF05970.14 GBG58743.1 - 3.4e-86 289.7 0.0 5.4e-86 289.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 GBG58743.1 - 2.7e-10 40.3 0.0 7.3e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG58743.1 - 0.0019 18.5 0.0 0.0087 16.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG58743.1 - 0.009 16.4 0.2 0.084 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG58743.1 - 0.064 13.5 0.0 0.31 11.3 0.0 2.3 1 0 0 1 1 1 0 AAA domain Herpes_BLRF2 PF05812.12 GBG58743.1 - 0.13 12.4 1.8 0.48 10.6 0.2 2.7 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein CENP-Q PF13094.6 GBG58743.1 - 1 9.5 8.0 0.31 11.2 2.8 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RVT_1 PF00078.27 GBG58744.1 - 1.9e-32 112.6 0.1 2.8e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG58744.1 - 1.2e-06 29.1 0.0 2.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58744.1 - 3e-06 27.7 0.0 6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG58744.1 - 3.4e-05 23.6 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG58744.1 - 0.00068 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease S6PP_C PF08472.10 GBG58744.1 - 0.013 15.4 0.0 0.83 9.5 0.0 2.3 1 1 1 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal RT_RNaseH_2 PF17919.1 GBG58744.1 - 0.092 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58745.1 - 6.8e-34 115.9 0.1 2.2e-33 114.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58745.1 - 1.2e-29 102.6 0.0 3.4e-29 101.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58745.1 - 2.3e-18 66.6 0.0 4.2e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG58745.1 - 6.2e-17 61.4 0.1 2.2e-16 59.7 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG58745.1 - 1.9e-06 27.7 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG58745.1 - 0.011 16.3 0.0 0.027 15.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG58745.1 - 0.012 16.2 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG58745.1 - 0.041 14.0 1.5 0.13 12.3 1.5 2.0 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG58745.1 - 0.067 13.5 0.0 0.28 11.5 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein Methyltransf_11 PF08241.12 GBG58747.1 - 6.4e-20 71.6 0.0 1.9e-19 70.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG58747.1 - 2.2e-16 60.3 0.0 7.6e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG58747.1 - 9.5e-12 45.0 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG58747.1 - 5.2e-11 43.2 0.0 1.2e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG58747.1 - 4.1e-10 39.4 0.0 6.9e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GBG58747.1 - 7.5e-09 35.6 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 GBG58747.1 - 0.0001 21.0 0.0 0.00015 20.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.11 GBG58747.1 - 0.001 18.1 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Nop PF01798.18 GBG58749.1 - 2.6e-88 295.4 0.0 2.6e-88 295.4 0.0 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GBG58749.1 - 3.6e-17 62.5 0.1 3.6e-17 62.5 0.1 3.1 4 0 0 4 4 4 1 NOP5NT (NUC127) domain HOOK PF05622.12 GBG58750.1 - 0.0035 15.6 7.2 0.0035 15.6 7.2 2.1 2 0 0 2 2 2 1 HOOK protein Lzipper-MIP1 PF14389.6 GBG58750.1 - 0.074 13.4 15.6 5.7 7.3 0.2 4.7 3 1 2 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 MbeD_MobD PF04899.12 GBG58750.1 - 0.13 12.4 8.1 0.21 11.7 1.2 3.2 2 1 0 3 3 3 0 MbeD/MobD like DUF5088 PF17008.5 GBG58750.1 - 0.14 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5088) APC_N_CC PF16689.5 GBG58750.1 - 0.7 10.0 9.3 15 5.8 0.2 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Phage_GPO PF05929.11 GBG58750.1 - 2.4 7.7 7.0 5.1 6.6 1.2 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase XhlA PF10779.9 GBG58750.1 - 3.4 7.9 7.3 0.34 11.2 1.1 2.4 2 1 0 2 2 2 0 Haemolysin XhlA APG6_N PF17675.1 GBG58750.1 - 3.7 8.1 27.4 0.11 13.0 5.5 2.7 1 1 0 2 2 2 0 Apg6 coiled-coil region Laminin_G_3 PF13385.6 GBG58751.1 - 6.3e-77 256.9 14.3 2.7e-19 69.8 0.4 12.4 12 2 0 12 12 12 7 Concanavalin A-like lectin/glucanases superfamily Filamin PF00630.19 GBG58751.1 - 1.7e-22 80.2 0.0 3.2e-11 43.9 0.0 4.8 4 0 0 4 4 4 3 Filamin/ABP280 repeat Kelch_6 PF13964.6 GBG58751.1 - 5.1e-22 77.4 7.5 3.9e-05 23.8 0.0 6.1 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 GBG58751.1 - 1.1e-20 73.1 17.1 0.00012 21.9 0.1 7.6 7 0 0 7 7 7 5 Kelch motif Kelch_1 PF01344.25 GBG58751.1 - 6.1e-19 67.3 3.4 1.6e-06 27.6 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GBG58751.1 - 1.1e-18 67.0 16.6 2.6e-06 27.4 0.1 7.1 5 1 1 6 6 6 5 Galactose oxidase, central domain TIG PF01833.24 GBG58751.1 - 1.5e-16 60.2 5.9 1.3e-07 31.6 0.0 5.5 5 0 0 5 5 4 2 IPT/TIG domain Gal_Lectin PF02140.18 GBG58751.1 - 2.9e-15 56.5 6.0 8.8e-12 45.3 0.0 3.1 3 0 0 3 3 3 2 Galactose binding lectin domain Kelch_3 PF13415.6 GBG58751.1 - 6.1e-15 55.1 9.9 0.0016 18.7 0.0 7.6 6 0 0 6 6 6 3 Galactose oxidase, central domain PA14 PF07691.12 GBG58751.1 - 3.4e-14 52.9 0.0 2.8e-13 49.9 0.0 2.4 2 0 0 2 2 2 1 PA14 domain Laminin_G_2 PF02210.24 GBG58751.1 - 2e-13 51.0 0.0 3.6 8.2 0.0 7.7 9 0 0 9 9 6 3 Laminin G domain Kelch_2 PF07646.15 GBG58751.1 - 1.6e-12 46.8 14.8 0.002 18.0 0.3 6.4 6 0 0 6 6 5 4 Kelch motif DUF2341 PF10102.9 GBG58751.1 - 1.9e-09 38.0 0.7 5.8e-09 36.4 0.1 2.2 2 0 0 2 2 1 1 Domain of unknown function (DUF2341) GLEYA PF10528.9 GBG58751.1 - 6.9e-05 23.2 0.0 0.00038 20.8 0.0 2.4 1 0 0 1 1 1 1 GLEYA domain Sialidase PF02973.16 GBG58751.1 - 0.00017 21.1 0.0 0.007 15.9 0.0 3.0 4 0 0 4 4 4 1 Sialidase, N-terminal domain Invasin_D3 PF09134.10 GBG58751.1 - 0.00031 21.0 0.3 0.81 10.0 0.0 4.1 4 0 0 4 4 4 1 Invasin, domain 3 Toxin_R_bind_N PF07953.12 GBG58751.1 - 0.0014 18.4 0.2 13 5.4 0.1 4.6 5 0 0 5 5 5 0 Clostridium neurotoxin, N-terminal receptor binding Nop14 PF04147.12 GBG58751.1 - 1.7 6.8 5.3 2.5 6.2 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 GBG58751.1 - 1.7 8.1 6.1 2.8 7.5 6.1 1.2 1 0 0 1 1 1 0 PPP4R2 RT_RNaseH_2 PF17919.1 GBG58752.1 - 2.5e-27 94.8 0.0 4.1e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58752.1 - 1.6e-24 86.2 0.0 2.9e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58752.1 - 1.2e-09 38.0 0.1 2.1e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG58752.1 - 0.53 8.4 7.9 0.65 8.1 7.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG58752.1 - 0.65 8.2 9.1 0.9 7.7 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG58752.1 - 3.2 7.1 10.6 4.2 6.7 10.6 1.1 1 0 0 1 1 1 0 SDA1 zf-RING_2 PF13639.6 GBG58753.1 - 1.6e-12 47.6 4.5 1.6e-12 47.6 4.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG58753.1 - 2.8e-10 39.9 5.2 2.8e-10 39.9 5.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 GBG58753.1 - 1.4e-09 38.0 3.5 1.4e-09 38.0 3.5 2.4 2 1 0 2 2 2 1 zinc-ribbon zf-RING_11 PF17123.5 GBG58753.1 - 4.1e-09 36.0 1.4 4.1e-09 36.0 1.4 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 GBG58753.1 - 2.4e-06 27.3 3.8 2.4e-06 27.3 3.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG58753.1 - 4e-06 27.0 7.2 4e-06 27.0 7.2 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GBG58753.1 - 2.7e-05 24.1 0.6 2.7e-05 24.1 0.6 2.5 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GBG58753.1 - 0.00041 20.1 3.6 0.00041 20.1 3.6 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GBG58753.1 - 0.00052 19.8 2.0 0.00052 19.8 2.0 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG58753.1 - 0.0011 18.9 3.5 0.0011 18.9 3.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GBG58753.1 - 0.0011 18.9 3.7 0.002 18.1 2.5 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GBG58753.1 - 0.019 14.6 3.8 0.019 14.6 3.8 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 GBG58753.1 - 0.27 11.1 2.2 0.36 10.7 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_16 PF17034.5 GBG58753.1 - 0.73 10.1 3.0 1 9.6 2.2 1.7 1 1 0 1 1 1 0 Zinc-ribbon like family zf-Nse PF11789.8 GBG58753.1 - 0.75 9.7 2.1 1.5 8.7 2.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-FPG_IleRS PF06827.14 GBG58753.1 - 1.1 9.2 8.5 0.45 10.4 4.2 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DZR PF12773.7 GBG58753.1 - 3.6 7.7 6.2 13 5.9 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 GBG58753.1 - 7.6 6.5 10.2 5.9 6.9 4.2 2.9 3 0 0 3 3 3 0 PHD-finger Met_10 PF02475.16 GBG58754.1 - 2.4e-60 203.7 0.0 9.6e-57 191.9 0.0 2.2 2 0 0 2 2 2 2 Met-10+ like-protein GRP PF07172.11 GBG58754.1 - 0.019 15.6 6.1 0.019 15.6 6.1 4.6 4 1 0 4 4 4 0 Glycine rich protein family Methyltransf_15 PF09445.10 GBG58754.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DNA_pol_phi PF04931.13 GBG58756.1 - 3.6 5.6 31.7 4.1 5.4 31.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 GBG58756.1 - 5.2 6.2 12.0 5.4 6.1 12.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 GBG58756.1 - 5.4 5.1 22.4 5.9 5.0 22.4 1.0 1 0 0 1 1 1 0 Nop14-like family ALMT PF11744.8 GBG58758.1 - 4.3 6.1 7.0 4.8 5.9 7.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 GBG58758.1 - 6.2 6.6 19.0 7.2 6.3 19.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG58758.1 - 9.2 4.9 12.4 10 4.8 12.4 1.0 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG58759.1 - 1.5e-33 114.8 0.0 2.6e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58759.1 - 1.7e-20 73.3 0.0 3.9e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG58759.1 - 1.3e-06 28.2 0.5 2.2e-06 27.5 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG58759.1 - 0.0095 15.7 0.6 0.019 14.8 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF3801 PF12687.7 GBG58759.1 - 0.27 11.3 9.8 0.39 10.8 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) PPP4R2 PF09184.11 GBG58759.1 - 0.43 10.1 18.0 0.63 9.6 18.0 1.1 1 0 0 1 1 1 0 PPP4R2 DUF4746 PF15928.5 GBG58759.1 - 0.73 9.2 18.4 1.2 8.5 18.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Na_trans_assoc PF06512.13 GBG58759.1 - 1.1 9.5 15.4 1.6 8.9 15.4 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated RNA_pol_Rpc4 PF05132.14 GBG58759.1 - 2.3 8.6 5.6 5.3 7.5 5.6 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 GBG58759.1 - 6.7 5.4 9.1 9.3 4.9 9.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Myb_DNA-bind_4 PF13837.6 GBG58760.1 - 7.4e-07 29.5 4.0 3.6e-06 27.3 1.0 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG58760.1 - 0.34 11.2 1.5 0.42 10.9 0.2 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG58760.1 - 0.71 10.0 2.2 1.8 8.7 2.2 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Lactamase_B PF00753.27 GBG58762.1 - 2.7e-11 43.9 2.5 3.8e-11 43.3 2.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GBG58762.1 - 6.7e-05 22.5 0.4 0.00014 21.4 0.3 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 GBG58762.1 - 0.00035 20.5 0.1 0.00078 19.4 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_3 PF13483.6 GBG58762.1 - 0.0035 17.3 0.1 0.013 15.4 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Zip PF02535.22 GBG58764.1 - 5.1e-11 42.4 4.3 5.1e-11 42.4 4.3 4.0 4 0 0 4 4 4 2 ZIP Zinc transporter Abhydro_lipase PF04083.16 GBG58765.1 - 7.3e-17 60.7 0.0 2.9e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GBG58765.1 - 9.9e-06 25.4 0.1 0.094 12.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG58765.1 - 1e-05 24.9 0.1 0.004 16.5 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG58765.1 - 0.00031 21.4 0.0 0.00079 20.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 GBG58765.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase RVT_1 PF00078.27 GBG58767.1 - 5.6e-37 127.4 0.0 7.6e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cys_Met_Meta_PP PF01053.20 GBG58768.1 - 8.9e-130 432.6 0.0 1e-129 432.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GBG58768.1 - 9.3e-08 31.4 0.1 1.4e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GBG58768.1 - 9.7e-07 28.4 0.2 1.4e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GBG58768.1 - 3.5e-06 26.5 0.1 6.5e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 GBG58768.1 - 0.0009 17.9 0.0 0.0017 16.9 0.0 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GBG58768.1 - 0.0026 16.7 0.1 0.0036 16.2 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.20 GBG58769.1 - 3.5e-126 420.8 0.0 4.3e-126 420.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GBG58769.1 - 6.4e-07 28.7 0.1 1.1e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GBG58769.1 - 7e-06 25.6 0.4 1.3e-05 24.7 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GBG58769.1 - 8.2e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 GBG58769.1 - 0.0077 14.8 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GBG58769.1 - 0.041 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein RVT_1 PF00078.27 GBG58770.1 - 0.0097 15.4 0.0 0.56 9.7 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG58771.1 - 0.009 16.3 0.0 0.019 15.2 0.0 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG58772.1 - 2.1e-25 89.6 0.1 3e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58772.1 - 2.7e-14 53.0 0.0 5.4e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58772.1 - 0.0012 19.0 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3381 PF11861.8 GBG58772.1 - 1.2 8.9 9.7 2 8.2 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.14 GBG58772.1 - 1.3 7.2 11.3 2 6.6 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG58772.1 - 2.5 7.9 8.3 4 7.2 8.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_C48 PF02902.19 GBG58773.1 - 2e-21 76.8 0.0 4.2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-RING_13 PF17977.1 GBG58773.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SDA1 PF05285.12 GBG58774.1 - 0.11 11.8 24.1 0.14 11.5 24.1 1.1 1 0 0 1 1 1 0 SDA1 DUF3807 PF12720.7 GBG58774.1 - 0.12 12.6 14.1 0.18 12.1 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2201_N PF13203.6 GBG58774.1 - 3.2 7.3 8.1 4.4 6.8 8.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain BUD22 PF09073.10 GBG58774.1 - 3.6 6.8 25.2 4.7 6.4 25.2 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG58774.1 - 3.8 7.0 11.8 6.1 6.3 11.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG58774.1 - 3.8 5.6 25.7 5 5.2 25.7 1.1 1 0 0 1 1 1 0 Nop14-like family Cys_Met_Meta_PP PF01053.20 GBG58775.1 - 1.4e-130 435.3 0.0 1.6e-130 435.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GBG58775.1 - 1.7e-08 33.8 0.1 2.7e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GBG58775.1 - 1e-06 28.3 1.4 1.8e-06 27.6 1.0 1.5 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GBG58775.1 - 4.2e-06 26.3 0.1 9.1e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GBG58775.1 - 2.4e-05 23.7 0.0 3.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 GBG58775.1 - 0.00075 18.1 0.0 0.0013 17.3 0.0 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GBG58775.1 - 0.0023 16.8 0.1 0.0033 16.3 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Stm1_N PF09598.10 GBG58776.1 - 0.77 10.6 4.8 4.5 8.2 4.8 2.4 1 0 0 1 1 1 0 Stm1 DDE_Tnp_4 PF13359.6 GBG58777.1 - 3.4e-21 75.6 0.0 1e-20 74.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG58777.1 - 1.7e-08 34.3 0.0 3.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG58777.1 - 0.053 13.2 0.0 0.9 9.1 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Pox_F11 PF04943.12 GBG58777.1 - 0.093 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Barwin PF00967.17 GBG58777.1 - 0.61 10.0 4.8 4.4 7.2 0.0 3.3 3 0 0 3 3 3 0 Barwin family Cys_Met_Meta_PP PF01053.20 GBG58778.1 - 6.7e-129 429.7 0.0 7.7e-129 429.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GBG58778.1 - 4.6e-08 32.4 0.1 6.9e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GBG58778.1 - 3.7e-06 26.5 0.2 5.8e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GBG58778.1 - 2.4e-05 23.8 0.1 5.4e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GBG58778.1 - 8.1e-05 21.9 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 GBG58778.1 - 0.0017 17.0 0.0 0.0029 16.2 0.0 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GBG58778.1 - 0.0031 16.4 0.1 0.0043 15.9 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.20 GBG58779.1 - 6.7e-129 429.7 0.0 7.7e-129 429.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GBG58779.1 - 4.6e-08 32.4 0.1 6.9e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GBG58779.1 - 3.7e-06 26.5 0.2 5.8e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GBG58779.1 - 2.4e-05 23.8 0.1 5.4e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GBG58779.1 - 9e-05 21.8 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 GBG58779.1 - 0.0017 17.0 0.0 0.0029 16.2 0.0 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GBG58779.1 - 0.0031 16.4 0.1 0.0043 15.9 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Rad9 PF04139.13 GBG58780.1 - 5.4e-64 216.0 0.0 6.8e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 GAGA_bind PF06217.12 GBG58781.1 - 4.7 7.4 24.2 6 7.1 24.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Apt1 PF10351.9 GBG58781.1 - 5.4 5.8 16.9 6.2 5.5 16.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spem1 PF15670.5 GBG58781.1 - 6.1 6.3 6.8 7.7 6.0 6.8 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 SLC12 PF03522.15 GBG58781.1 - 6.6 5.6 20.0 9.1 5.2 20.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 RT_RNaseH PF17917.1 GBG58783.1 - 1.9e-27 95.6 0.3 4.4e-27 94.4 0.3 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58783.1 - 1.5e-20 73.1 0.1 3.6e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58783.1 - 1.3e-18 66.9 0.0 2.6e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG58783.1 - 4.5e-14 52.6 0.0 1.1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG58783.1 - 0.0061 16.8 0.0 0.027 14.7 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG58783.1 - 0.0088 16.0 0.4 0.022 14.7 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 GBG58783.1 - 0.058 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC_4 PF14392.6 GBG58783.1 - 1.1 9.1 4.6 0.52 10.1 0.8 2.5 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC PF00098.23 GBG58783.1 - 1.4 9.1 4.9 3.5 7.9 4.9 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG58784.1 - 2e-29 102.7 0.1 3.1e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58784.1 - 3.3e-24 84.8 0.0 8.6e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58784.1 - 5.5e-23 81.3 0.0 1.4e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58784.1 - 8.8e-18 64.2 1.4 2.4e-17 62.8 1.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG58784.1 - 4.6e-08 33.3 0.0 1.6e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG58784.1 - 8.9e-06 26.3 0.0 1.8e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58784.1 - 3.7e-05 24.2 0.0 7.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG58784.1 - 0.0002 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG58784.1 - 0.0027 17.5 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG58784.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG58785.1 - 1.1e-24 87.3 0.0 2.2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) P4Ha_N PF08336.11 GBG58785.1 - 0.0092 16.0 0.5 1.4 8.9 0.1 2.4 2 0 0 2 2 2 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2730 PF10805.8 GBG58785.1 - 0.0094 16.0 0.3 0.2 11.7 0.3 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2730) Cast PF10174.9 GBG58785.1 - 0.048 11.9 1.2 0.081 11.1 1.2 1.3 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ADIP PF11559.8 GBG58785.1 - 0.055 13.6 2.8 0.13 12.3 2.8 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FUSC PF04632.12 GBG58785.1 - 0.45 9.0 1.9 0.74 8.3 1.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FliJ PF02050.16 GBG58785.1 - 1.1 9.5 6.1 0.27 11.5 0.4 2.5 3 0 0 3 3 3 0 Flagellar FliJ protein RT_RNaseH_2 PF17919.1 GBG58786.1 - 3.1e-28 97.7 0.0 5.2e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58786.1 - 6.3e-26 90.7 0.0 1.1e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58786.1 - 2.4e-17 63.2 0.0 3.7e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG58786.1 - 0.018 14.9 0.0 0.76 9.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) GIY-YIG PF01541.24 GBG58787.1 - 4e-06 27.0 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain CDC48_N PF02359.18 GBG58787.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Ribosomal_S3_C PF00189.20 GBG58787.1 - 0.054 14.0 0.5 0.19 12.3 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S3, C-terminal domain Presenilin PF01080.17 GBG58788.1 - 6 5.5 29.0 3 6.5 15.7 2.1 2 0 0 2 2 2 0 Presenilin Apt1 PF10351.9 GBG58790.1 - 0.48 9.2 8.3 0.73 8.6 8.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PolyG_pol PF01518.16 GBG58793.1 - 0.064 11.9 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 Sigma NS protein DUF3242 PF11586.8 GBG58793.1 - 0.094 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) RVT_1 PF00078.27 GBG58794.1 - 6.8e-21 74.8 0.1 1.4e-20 73.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG58794.1 - 1.2e-05 25.1 2.9 2.3e-05 24.3 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG58794.1 - 0.00025 20.8 0.0 0.0024 17.6 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG58794.1 - 0.0035 18.0 0.0 0.011 16.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58794.1 - 0.0038 17.7 0.0 0.0091 16.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG58794.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG58794.1 - 0.041 13.7 3.5 0.081 12.8 3.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Sporozoite_P67 PF05642.11 GBG58794.1 - 1.8 6.6 9.0 2.9 5.9 9.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FRQ PF09421.10 GBG58794.1 - 4.3 5.2 8.0 6.5 4.6 8.0 1.1 1 0 0 1 1 1 0 Frequency clock protein zf-CCHC PF00098.23 GBG58795.1 - 0.0003 20.7 1.1 0.0003 20.7 1.1 2.1 2 0 0 2 2 2 1 Zinc knuckle Ubiq_cyt_C_chap PF03981.12 GBG58795.1 - 0.0041 17.2 1.3 0.007 16.4 1.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HemY_N PF07219.13 GBG58795.1 - 0.044 14.0 2.4 0.099 12.9 2.4 1.5 1 0 0 1 1 1 0 HemY protein N-terminus zf-CCHC_2 PF13696.6 GBG58795.1 - 0.054 13.3 1.7 0.094 12.6 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle MbeD_MobD PF04899.12 GBG58795.1 - 0.32 11.1 3.9 0.83 9.8 3.9 1.7 1 0 0 1 1 1 0 MbeD/MobD like Integrase_H2C2 PF17921.1 GBG58796.1 - 1.6e-19 69.8 1.1 3.2e-19 68.8 1.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain O-FucT PF10250.9 GBG58796.1 - 1.1e-09 38.5 0.0 4.4e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase rve PF00665.26 GBG58796.1 - 4.9e-09 36.4 0.0 2.3e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain SR-25 PF10500.9 GBG58796.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-H2C2 PF09337.10 GBG58796.1 - 0.14 12.4 0.3 0.39 11.0 0.3 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Dehydrin PF00257.19 GBG58796.1 - 0.23 12.0 0.2 0.37 11.3 0.2 1.2 1 0 0 1 1 1 0 Dehydrin PRIMA1 PF16101.5 GBG58796.1 - 0.24 11.4 7.4 0.59 10.2 7.4 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG58796.1 - 0.27 10.7 2.8 0.43 10.0 2.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1216 PF06746.11 GBG58796.1 - 0.52 10.3 2.2 0.95 9.5 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) ArfGap PF01412.18 GBG58797.1 - 1.8e-38 131.2 0.0 3e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf C2 PF00168.30 GBG58797.1 - 4.6e-26 91.1 0.0 9.1e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain zf-B_box PF00643.24 GBG58797.1 - 0.24 11.6 0.9 23 5.2 0.1 2.2 2 0 0 2 2 2 0 B-box zinc finger zf-dskA_traR PF01258.17 GBG58797.1 - 0.27 11.2 1.9 0.52 10.3 0.3 2.0 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Chromo PF00385.24 GBG58798.1 - 5.6e-11 42.2 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PRA1 PF03208.19 GBG58800.1 - 6.9e-41 139.2 0.5 8.9e-41 138.9 0.5 1.1 1 0 0 1 1 1 1 PRA1 family protein ATP-synt_I PF03899.15 GBG58800.1 - 0.00036 20.9 5.2 0.081 13.3 0.1 2.2 2 0 0 2 2 2 2 ATP synthase I chain Nop14 PF04147.12 GBG58801.1 - 2.7 6.1 4.4 3.1 5.9 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_4 PF13837.6 GBG58802.1 - 0.00067 20.0 0.2 0.0023 18.3 0.2 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG58803.1 - 5.8e-30 104.0 0.0 8.8e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG58803.1 - 3.3e-15 56.2 0.0 5.8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG58803.1 - 0.003 17.2 0.1 2.3 7.8 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain Trimer_CC PF08954.11 GBG58804.1 - 0.015 14.8 2.6 0.015 14.8 2.6 2.9 2 0 0 2 2 2 0 Trimerisation motif Pox_A_type_inc PF04508.12 GBG58804.1 - 0.21 11.5 9.4 2.9 7.9 0.1 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF484 PF04340.12 GBG58804.1 - 0.25 11.0 3.5 0.11 12.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF484 CCDC92 PF14916.6 GBG58804.1 - 0.85 9.4 4.2 16 5.3 0.4 3.8 2 1 1 3 3 3 0 Coiled-coil domain of unknown function BRE1 PF08647.11 GBG58804.1 - 3.9 7.6 14.6 2.9 8.0 2.4 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 GBG58804.1 - 8.9 7.0 12.6 1.6e+02 3.0 2.4 3.9 1 1 2 3 3 3 0 Initiation control protein YabA Methyltransf_12 PF08242.12 GBG58805.1 - 0.015 16.0 4.8 3.1 8.6 0.9 2.7 2 0 0 2 2 2 0 Methyltransferase domain Orf78 PF06024.12 GBG58805.1 - 0.088 13.1 7.5 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) DUF2076 PF09849.9 GBG58805.1 - 1.6 8.7 27.9 0.69 9.9 11.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) BUD22 PF09073.10 GBG58805.1 - 3.2 7.0 12.6 4.5 6.5 12.6 1.2 1 0 0 1 1 1 0 BUD22 Xan_ur_permease PF00860.20 GBG58806.1 - 5.3e-63 213.0 27.8 2.6e-35 121.9 9.2 2.1 2 0 0 2 2 2 2 Permease family MFS_MOT1 PF16983.5 GBG58806.1 - 7.9 6.9 23.9 8.5 6.8 4.8 3.9 2 1 1 3 3 3 0 Molybdate transporter of MFS superfamily Myb_DNA-bind_4 PF13837.6 GBG58808.1 - 3e-07 30.7 1.2 6.8e-07 29.6 1.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG58808.1 - 0.0091 16.3 1.4 0.043 14.1 0.6 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG58808.1 - 0.21 11.7 0.7 0.47 10.6 0.7 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-CCHC_3 PF13917.6 GBG58810.1 - 0.018 15.0 1.8 0.033 14.2 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG58810.1 - 0.14 12.4 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG58811.1 - 4.8e-22 77.9 0.0 8.2e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58811.1 - 9.4e-22 77.3 0.0 1.8e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58811.1 - 6.2e-17 61.5 0.3 1.2e-16 60.5 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain UvrD-helicase PF00580.21 GBG58811.1 - 1.3e-07 31.5 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain RVT_1 PF00078.27 GBG58811.1 - 0.0001 21.9 0.2 0.0004 20.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_19 PF13245.6 GBG58811.1 - 0.009 16.4 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain rve PF00665.26 GBG58811.1 - 0.011 15.9 0.0 0.035 14.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain ResIII PF04851.15 GBG58811.1 - 0.019 15.0 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Autophagy_N PF03986.13 GBG58812.1 - 0.04 13.9 3.3 0.057 13.4 3.3 1.2 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Na_trans_assoc PF06512.13 GBG58812.1 - 0.72 10.1 12.1 0.79 10.0 12.1 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG58812.1 - 1.7 6.7 20.8 1.9 6.6 20.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG58812.1 - 1.8 7.9 11.5 2.2 7.6 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 GBG58812.1 - 8.3 5.7 22.3 9.1 5.6 22.3 1.1 1 0 0 1 1 1 0 SDA1 IspD PF01128.19 GBG58813.1 - 8.4e-38 130.3 0.0 1.1e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 GBG58813.1 - 1.3e-09 38.6 0.0 2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 GBG58813.1 - 0.025 14.1 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase Myb_DNA-bind_4 PF13837.6 GBG58814.1 - 4.5e-06 27.0 1.4 8.7e-06 26.0 0.4 1.9 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG58814.1 - 0.0067 16.5 0.5 0.04 14.0 0.1 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Epimerase PF01370.21 GBG58815.1 - 1.9e-16 60.3 0.0 1.8e-15 57.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GBG58815.1 - 4.5e-10 39.7 0.0 7.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GBG58815.1 - 6.9e-10 38.8 0.0 0.0005 19.6 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GBG58815.1 - 0.002 17.3 0.0 0.47 9.5 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Glyco_trans_4_4 PF13579.6 GBG58815.1 - 0.054 13.9 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain adh_short PF00106.25 GBG58815.1 - 0.06 12.8 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox PF00070.27 GBG58815.1 - 0.068 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GBG58815.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 GBG58815.1 - 0.18 11.3 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Pyr_redox_2 PF07992.14 GBG58815.1 - 0.19 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF659 PF04937.15 GBG58817.1 - 2.7e-10 40.3 0.0 4.1e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG58817.1 - 6.1e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_Tnp_4 PF13359.6 GBG58818.1 - 8.3e-33 113.3 0.0 6.1e-32 110.5 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG58818.1 - 2.2e-13 50.3 0.0 3.8e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG58818.1 - 0.0014 18.3 0.4 0.72 9.4 0.0 2.8 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG58818.1 - 0.071 13.5 0.1 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Abhydrolase_6 PF12697.7 GBG58820.1 - 2e-17 64.6 10.0 1.4e-16 61.8 6.4 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG58820.1 - 4.8e-15 55.9 0.0 2.3e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG58820.1 - 8.3e-11 41.6 3.0 0.00025 20.4 0.0 2.9 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GBG58820.1 - 5.6e-05 22.7 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 GBG58820.1 - 0.00013 21.9 0.2 0.016 15.1 0.3 2.4 2 0 0 2 2 2 1 Serine hydrolase DUF1180 PF06679.12 GBG58820.1 - 0.026 15.0 0.4 0.076 13.4 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Abhydrolase_4 PF08386.10 GBG58820.1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.14 GBG58820.1 - 0.079 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family FSH1 PF03959.13 GBG58820.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) SH2 PF00017.24 GBG58820.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 SH2 domain Tocopherol_cycl PF14249.6 GBG58821.1 - 6.3e-142 472.6 4.7 9.2e-142 472.1 4.7 1.2 1 0 0 1 1 1 1 Tocopherol cyclase His_Phos_1 PF00300.22 GBG58822.1 - 1.6e-68 230.3 0.0 8.6e-42 143.0 0.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AWS PF17907.1 GBG58822.1 - 0.0016 18.4 1.0 0.0049 16.9 1.0 1.8 1 0 0 1 1 1 1 AWS domain zf-RanBP PF00641.18 GBG58823.1 - 7.7e-12 44.3 17.8 1.8e-06 27.2 2.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 GBG58823.1 - 8e-09 35.2 0.0 2.9e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RecR PF02132.15 GBG58823.1 - 0.97 9.1 8.2 0.063 12.8 1.3 2.3 2 0 0 2 2 2 0 RecR protein Trypsin PF00089.26 GBG58824.1 - 2.9e-24 86.1 0.0 4.6e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin MA3 PF02847.17 GBG58825.1 - 2.7e-108 355.9 4.3 2.7e-26 91.7 0.1 4.1 4 0 0 4 4 4 4 MA3 domain Arm_3 PF16186.5 GBG58825.1 - 0.014 14.9 4.3 0.35 10.5 0.1 3.3 3 0 0 3 3 3 0 Atypical Arm repeat DUF3837 PF12939.7 GBG58825.1 - 0.019 15.3 0.1 57 4.2 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3837) Brix PF04427.18 GBG58826.1 - 4.7e-42 144.3 0.3 6.5e-42 143.8 0.3 1.2 1 0 0 1 1 1 1 Brix domain PPL5 PF18168.1 GBG58826.1 - 0.058 12.7 1.0 0.084 12.2 1.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 tRNA-synt_1c PF00749.21 GBG58826.1 - 1.7 7.5 4.9 2.6 6.8 4.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain NARP1 PF12569.8 GBG58826.1 - 3.5 6.4 8.3 4.8 6.0 8.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PIEZO PF15917.5 GBG58826.1 - 6.3 6.2 6.8 10 5.5 6.8 1.2 1 0 0 1 1 1 0 Piezo RVT_1 PF00078.27 GBG58827.1 - 9.1e-33 113.6 0.1 1.8e-32 112.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58827.1 - 8.5e-32 109.2 0.1 1.7e-31 108.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58827.1 - 7e-28 97.0 0.5 2.6e-27 95.1 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58827.1 - 2.1e-18 66.2 0.1 4.7e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG58827.1 - 1.2e-05 25.5 0.1 5.3e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger RRM_1 PF00076.22 GBG58828.1 - 4.6e-06 26.4 0.0 0.00018 21.2 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GBG58829.1 - 4.7e-06 26.3 0.0 0.00018 21.2 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 GBG58830.1 - 2.9e-177 591.5 0.0 3.9e-153 511.7 0.0 3.1 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 GBG58830.1 - 0.00012 22.4 0.8 0.67 10.3 0.1 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Tubulin PF00091.25 GBG58831.1 - 3e-64 216.8 0.0 4.2e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG58831.1 - 1.8e-20 73.4 0.4 2.5e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GBG58831.1 - 0.006 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 GBG58831.1 - 0.029 13.6 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 GBG58831.1 - 0.031 14.0 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain ADK PF00406.22 GBG58832.1 - 1.1e-89 298.3 0.0 1.9e-44 151.4 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 GBG58832.1 - 1.2e-60 203.8 0.0 6.4e-31 107.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GBG58832.1 - 2.2e-10 41.2 0.0 0.00048 20.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GBG58832.1 - 4.9e-08 33.2 0.0 0.00061 20.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 GBG58832.1 - 4.1e-07 29.8 0.7 1.4 8.6 0.1 4.2 3 1 1 4 4 4 3 Thymidylate kinase AAA_19 PF13245.6 GBG58832.1 - 0.00083 19.7 0.0 1.1 9.6 0.1 2.5 2 0 0 2 2 2 2 AAA domain GvpK PF05121.12 GBG58832.1 - 0.0077 16.2 0.0 0.27 11.3 0.0 3.1 4 0 0 4 4 4 1 Gas vesicle protein K Zeta_toxin PF06414.12 GBG58832.1 - 0.012 14.9 0.0 0.95 8.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 GBG58832.1 - 0.037 14.4 0.2 6.1 7.3 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 GBG58833.1 - 2.5e-57 193.0 0.0 2.9e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG58833.1 - 3.7e-33 114.3 0.0 5.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG58833.1 - 1.2e-17 63.9 0.0 1.6e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GBG58833.1 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG58833.1 - 0.00012 22.1 0.1 0.037 13.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GBG58833.1 - 0.00022 20.7 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GBG58833.1 - 0.0018 17.7 0.0 0.0033 16.9 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GBG58833.1 - 0.0029 17.2 0.0 0.012 15.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GBG58833.1 - 0.0092 16.4 0.0 0.033 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 GBG58833.1 - 0.015 15.0 0.2 0.046 13.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG58833.1 - 0.017 14.9 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG58833.1 - 0.04 14.2 0.1 0.15 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 GBG58833.1 - 0.11 11.8 0.1 0.27 10.4 0.1 1.6 1 1 0 1 1 1 0 Septin DUF815 PF05673.13 GBG58833.1 - 0.11 11.6 0.0 0.57 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 GBG58833.1 - 0.13 12.8 0.1 0.15 12.6 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 GBG58833.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Acid_phosphat_B PF03767.14 GBG58834.1 - 3.8e-53 180.4 0.0 4.5e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase PF00702.26 GBG58834.1 - 0.02 15.2 0.2 7.5 6.8 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 GBG58834.1 - 0.038 13.5 0.6 1.4 8.3 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) HAD_2 PF13419.6 GBG58834.1 - 0.19 11.8 0.0 12 5.9 0.0 2.2 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HOOK PF05622.12 GBG58835.1 - 0.0012 17.1 17.9 0.0012 17.1 17.9 3.9 3 1 0 3 3 3 2 HOOK protein ERM PF00769.19 GBG58835.1 - 0.0037 17.1 29.0 0.0037 17.1 29.0 7.0 3 2 2 5 5 5 1 Ezrin/radixin/moesin family DUF4988 PF16378.5 GBG58835.1 - 4.8 6.8 5.8 34 4.0 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function BCDHK_Adom3 PF10436.9 GBG58838.1 - 1.2e-55 187.7 0.0 1.7e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GBG58838.1 - 4e-14 53.1 0.0 6.8e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GBG58838.1 - 0.0007 19.4 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase COPI_C PF06957.11 GBG58839.1 - 0.0023 16.7 0.0 0.0051 15.6 0.0 1.5 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Fis1_TPR_C PF14853.6 GBG58839.1 - 0.014 15.4 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Coatomer_WDAD PF04053.14 GBG58839.1 - 0.018 14.1 0.0 0.082 11.9 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region TPR_2 PF07719.17 GBG58839.1 - 0.048 13.8 0.3 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat VPS9 PF02204.18 GBG58841.1 - 2e-30 105.1 0.0 3.4e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GBG58841.1 - 8.5e-10 38.8 0.0 3.7e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) VPS9 PF02204.18 GBG58842.1 - 2.2e-30 104.9 0.0 3.7e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GBG58842.1 - 9.5e-10 38.7 0.0 4e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) RT_RNaseH PF17917.1 GBG58843.1 - 2e-25 89.1 0.0 4.5e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58843.1 - 4.1e-17 62.0 0.0 7.5e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG58843.1 - 0.0017 18.2 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG58843.1 - 0.0019 18.8 0.0 0.0052 17.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG58843.1 - 0.029 14.2 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG58843.1 - 0.029 14.9 0.0 0.1 13.2 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HTH_32 PF13565.6 GBG58843.1 - 0.67 10.6 10.9 0.19 12.4 0.3 3.9 3 1 1 4 4 4 0 Homeodomain-like domain TFIIF_alpha PF05793.12 GBG58843.1 - 0.87 8.1 15.3 0.071 11.7 10.6 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) O-FucT PF10250.9 GBG58844.1 - 3.4e-12 46.7 0.0 3.1e-06 27.1 0.0 3.1 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase SPX PF03105.19 GBG58844.1 - 7e-05 22.9 0.9 7e-05 22.9 0.9 1.1 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 GBG58844.1 - 0.025 13.4 3.1 0.032 13.1 3.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 GBG58844.1 - 0.048 12.2 3.2 0.056 12.0 3.2 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_transf_11 PF01531.16 GBG58844.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 11 Pacs-1 PF10254.9 GBG58844.1 - 1.1 8.1 3.6 1.6 7.6 3.6 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein CDC27 PF09507.10 GBG58844.1 - 2.4 7.5 6.9 3.4 7.0 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1180 PF06679.12 GBG58844.1 - 2.4 8.6 7.5 4.9 7.6 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SDA1 PF05285.12 GBG58845.1 - 5 6.4 18.3 7 6.0 18.3 1.2 1 0 0 1 1 1 0 SDA1 Apt1 PF10351.9 GBG58845.1 - 9.6 4.9 6.3 13 4.5 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Homeodomain PF00046.29 GBG58849.1 - 7.5e-17 60.9 4.8 1.3e-16 60.2 4.8 1.4 1 0 0 1 1 1 1 Homeodomain HALZ PF02183.18 GBG58849.1 - 1.7e-06 28.1 2.8 4.1e-06 26.9 2.8 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper KASH_CCD PF14662.6 GBG58849.1 - 0.0019 18.0 5.0 0.0038 17.1 5.0 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Homeobox_KN PF05920.11 GBG58849.1 - 0.0036 17.2 0.2 0.0067 16.3 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain DivIC PF04977.15 GBG58849.1 - 0.0038 17.0 0.5 0.009 15.8 0.5 1.6 1 0 0 1 1 1 1 Septum formation initiator JIP_LZII PF16471.5 GBG58849.1 - 0.061 13.5 0.3 0.15 12.2 0.3 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF465 PF04325.13 GBG58849.1 - 0.092 12.8 1.2 0.21 11.7 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) YabA PF06156.13 GBG58849.1 - 0.092 13.4 0.1 0.35 11.5 0.1 1.9 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_2 PF07716.15 GBG58849.1 - 0.17 12.0 2.2 0.52 10.4 2.2 1.8 1 0 0 1 1 1 0 Basic region leucine zipper BUD22 PF09073.10 GBG58851.1 - 0.47 9.7 16.2 0.62 9.4 16.2 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG58851.1 - 1.5 7.0 18.1 2 6.6 18.1 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 GBG58851.1 - 3.4 8.0 8.0 6 7.2 8.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 GBG58851.1 - 3.6 6.9 18.3 4.7 6.5 18.3 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 GBG58851.1 - 8.3 4.8 9.1 12 4.3 9.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RVT_1 PF00078.27 GBG58855.1 - 1.3e-21 77.1 0.3 2.3e-21 76.4 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG58856.1 - 1.9e-26 92.9 0.0 4.5e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG58856.1 - 8e-11 42.2 0.1 2.2e-10 40.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG58856.1 - 7.6e-09 35.8 0.0 2.6e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG58856.1 - 8.6e-07 29.5 0.0 3.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG58856.1 - 9.3e-07 28.7 0.0 2.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG58856.1 - 1.4e-05 25.0 0.3 0.0024 17.9 0.0 2.9 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG58856.1 - 0.0001 22.8 0.4 0.00057 20.4 0.0 2.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG58856.1 - 0.036 13.9 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG58856.1 - 0.12 12.7 0.0 1.4 9.3 0.0 2.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Integrase_H2C2 PF17921.1 GBG58857.1 - 4.6e-17 61.9 0.0 8.7e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG58857.1 - 1.5e-11 44.5 4.3 1.6e-11 44.4 1.1 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58857.1 - 0.0012 18.8 2.1 0.0022 18.0 0.3 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase UvrA_inter PF17760.1 GBG58857.1 - 0.0039 17.2 0.0 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 UvrA interaction domain DUF1126 PF06565.12 GBG58858.1 - 2e-77 255.8 0.2 3.7e-33 113.5 0.0 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 GBG58858.1 - 0.00046 20.6 0.0 0.00091 19.6 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair Asp_protease_2 PF13650.6 GBG58859.1 - 5.6e-07 30.1 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58859.1 - 1.6e-05 25.4 0.0 6.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG58859.1 - 2e-05 24.3 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG58859.1 - 0.0028 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease FlxA PF14282.6 GBG58859.1 - 0.0087 16.0 0.6 0.043 13.8 0.6 2.2 1 0 0 1 1 1 1 FlxA-like protein Retrotrans_gag PF03732.17 GBG58859.1 - 0.11 12.8 4.6 0.12 12.6 0.4 2.9 2 1 1 3 3 3 0 Retrotransposon gag protein PsbP PF01789.16 GBG58860.1 - 1.8e-28 99.6 0.3 2.6e-28 99.1 0.3 1.2 1 0 0 1 1 1 1 PsbP PsbQ PF05757.11 GBG58860.1 - 0.0028 17.4 2.9 0.005 16.6 2.9 1.4 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) RVT_1 PF00078.27 GBG58861.1 - 1.3e-20 73.9 0.2 3.5e-20 72.5 0.2 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ARS2 PF04959.13 GBG58862.1 - 6.7e-28 98.4 0.1 6.7e-28 98.4 0.1 3.0 3 0 0 3 3 3 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 GBG58862.1 - 5.3e-23 81.3 0.4 1.1e-22 80.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) PAP_assoc PF03828.19 GBG58863.1 - 4.3e-12 46.1 0.0 1.1e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GBG58863.1 - 4e-10 39.9 0.0 4e-10 39.9 0.0 2.8 2 1 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 GBG58863.1 - 0.00046 20.2 1.8 0.00081 19.4 0.0 2.1 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase DDHD PF02862.17 GBG58863.1 - 1.5 9.0 3.9 8 6.5 2.7 2.3 2 0 0 2 2 2 0 DDHD domain CIAPIN1 PF05093.13 GBG58864.1 - 2.8e-20 72.7 13.2 3.2e-15 56.5 2.8 2.8 2 1 1 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_8 PF05148.15 GBG58864.1 - 0.0021 18.0 0.0 0.0028 17.5 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 GBG58864.1 - 0.057 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GBG58864.1 - 0.12 13.2 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Trypan_PARP PF05887.11 GBG58866.1 - 0.0058 16.6 24.6 0.0058 16.6 24.6 1.9 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) Atrophin-1 PF03154.15 GBG58866.1 - 2.7 6.2 8.6 2.6 6.2 8.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family LAP1C PF05609.12 GBG58866.1 - 6.6 5.7 21.4 7.6 5.5 21.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF1062 PF06353.12 GBG58866.1 - 9.9 7.0 7.9 1.6e+02 3.1 7.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1062) MAPEG PF01124.18 GBG58867.1 - 1.9e-24 86.0 1.1 2.2e-24 85.8 1.1 1.0 1 0 0 1 1 1 1 MAPEG family DUF3080 PF11279.8 GBG58867.1 - 0.067 12.4 0.1 0.087 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Dehydratase_MU PF02288.15 GBG58868.1 - 0.15 11.9 0.3 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Dehydratase medium subunit Dynactin_p22 PF07426.11 GBG58869.1 - 4.2e-07 30.0 0.8 5.5e-07 29.6 0.1 1.5 2 0 0 2 2 2 1 Dynactin subunit p22 DUF484 PF04340.12 GBG58869.1 - 0.045 13.4 0.6 0.065 12.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF484 RVT_1 PF00078.27 GBG58871.1 - 2.4e-30 105.7 0.1 4.3e-30 104.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58871.1 - 5.4e-28 97.0 0.0 8.3e-15 54.6 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58871.1 - 8.9e-27 93.4 0.0 2.2e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58871.1 - 5.8e-15 55.1 0.5 2.2e-14 53.3 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG58871.1 - 2.8e-10 40.4 0.0 9e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG58871.1 - 7e-05 23.0 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger TIM PF00121.18 GBG58872.1 - 8.2e-58 195.6 0.1 1.3e-46 159.0 0.0 2.0 1 1 1 2 2 2 2 Triosephosphate isomerase CENP-Q PF13094.6 GBG58873.1 - 0.00094 19.4 3.6 0.002 18.4 3.6 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF16 PF01519.16 GBG58873.1 - 0.025 15.1 2.0 1.1 9.8 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 GBG58873.1 - 0.028 14.9 0.4 0.66 10.5 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SWI2_SNF2 PF18766.1 GBG58873.1 - 0.035 13.8 0.9 0.056 13.1 0.9 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AP1AR PF15745.5 GBG58873.1 - 0.041 13.5 1.3 0.067 12.8 1.3 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF4407 PF14362.6 GBG58873.1 - 1.5 8.1 5.5 0.88 8.9 2.9 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 GBG58873.1 - 2.7 8.5 6.3 8.3 6.9 1.6 2.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) RVT_1 PF00078.27 GBG58874.1 - 7.3e-29 100.9 0.0 1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58874.1 - 2e-07 31.0 0.0 4.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LRAT PF04970.13 GBG58877.1 - 2.2e-16 60.3 0.1 7.6e-10 39.2 0.0 3.0 2 1 1 3 3 3 2 Lecithin retinol acyltransferase TPKR_C2 PF16920.5 GBG58879.1 - 0.061 13.5 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain GOLD_2 PF13897.6 GBG58880.1 - 0.0025 18.3 11.3 0.097 13.2 0.1 3.2 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking MukE PF04288.13 GBG58880.1 - 0.024 13.6 0.4 0.038 12.9 0.4 1.2 1 0 0 1 1 1 0 MukE-like family T2SSL PF05134.13 GBG58881.1 - 0.089 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L TPR_12 PF13424.6 GBG58882.1 - 7.7e-16 58.1 12.7 1.6e-07 31.5 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 GBG58882.1 - 5.8e-11 41.6 11.0 0.0055 16.6 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG58882.1 - 5.3e-08 32.4 21.3 0.0095 16.0 1.4 5.5 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 GBG58882.1 - 9.4e-08 31.6 22.9 0.0057 16.4 1.8 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG58882.1 - 3.4e-06 26.8 8.2 0.46 10.8 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG58882.1 - 0.0014 18.8 10.1 0.088 13.0 0.1 4.3 2 1 2 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 GBG58882.1 - 0.0019 18.3 0.7 0.0076 16.3 0.7 2.0 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 GBG58882.1 - 0.13 13.0 9.4 3.6 8.4 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG58882.1 - 0.13 12.1 18.2 1.8 8.6 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 GBG58882.1 - 0.18 11.9 1.4 10 6.3 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 ComR_TPR PF18710.1 GBG58882.1 - 0.22 11.0 0.0 4.8 6.7 0.0 2.1 2 0 0 2 2 2 0 ComR tetratricopeptide TPR_16 PF13432.6 GBG58882.1 - 0.26 12.0 21.9 0.077 13.7 1.0 4.6 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG58882.1 - 0.51 11.3 17.9 0.34 11.9 0.2 6.1 5 2 2 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG58882.1 - 1.5 9.4 5.1 75 4.0 0.1 4.4 4 1 0 4 4 3 0 Tetratricopeptide repeat SDA1 PF05285.12 GBG58883.1 - 0.25 10.7 8.2 0.22 10.9 8.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG58883.1 - 0.25 9.5 9.1 0.26 9.4 9.1 1.0 1 0 0 1 1 1 0 Nop14-like family Pes-10 PF07149.11 GBG58883.1 - 2.8 6.9 6.4 2.6 7.0 6.4 1.1 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 GBG58883.1 - 6.3 5.0 8.5 7.1 4.8 8.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Endostatin PF06482.11 GBG58884.1 - 0.24 10.9 4.9 0.38 10.2 4.9 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Macoilin PF09726.9 GBG58884.1 - 0.32 9.5 5.8 0.61 8.6 5.8 1.4 1 0 0 1 1 1 0 Macoilin family PP2C PF00481.21 GBG58885.1 - 1.3e-32 113.4 0.0 3.7e-32 112.0 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GBG58885.1 - 7.5e-06 26.0 0.0 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GBG58885.1 - 0.0026 17.4 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C PIN_10 PF18478.1 GBG58885.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 PIN like domain zinc_ribbon_9 PF14369.6 GBG58885.1 - 0.36 11.1 2.1 1.7 9.0 2.1 2.2 1 1 0 1 1 1 0 zinc-ribbon TFIIE-A_C PF11521.8 GBG58885.1 - 6.7 7.1 13.8 0.053 13.8 2.7 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha MFS_5 PF05631.14 GBG58886.1 - 1.2e-48 165.8 9.2 2.4e-34 118.8 1.1 3.1 3 0 0 3 3 3 3 Sugar-tranasporters, 12 TM rve PF00665.26 GBG58886.1 - 3.1e-08 33.8 0.2 1.7e-07 31.4 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain MFS_1 PF07690.16 GBG58886.1 - 0.2 10.6 11.2 0.026 13.4 1.0 2.2 2 0 0 2 2 2 0 Major Facilitator Superfamily DUF659 PF04937.15 GBG58887.1 - 3.2e-07 30.3 0.0 0.00058 19.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) peroxidase PF00141.23 GBG58888.1 - 1.2e-40 139.6 0.0 1.8e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase IMUP PF15761.5 GBG58888.1 - 4.3 8.1 7.1 8.8 7.1 7.1 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Mu-like_Pro PF10123.9 GBG58889.1 - 0.0052 16.4 2.4 0.0075 15.9 2.4 1.4 1 0 0 1 1 1 1 Mu-like prophage I protein Tom22 PF04281.13 GBG58889.1 - 0.0067 16.2 0.2 0.016 15.0 0.1 1.7 1 1 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 YabA PF06156.13 GBG58889.1 - 0.018 15.7 0.3 0.052 14.2 0.0 1.9 2 0 0 2 2 2 0 Initiation control protein YabA Sporozoite_P67 PF05642.11 GBG58889.1 - 0.035 12.2 3.9 0.045 11.8 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AcylCoA_dehyd_C PF12186.8 GBG58889.1 - 0.039 14.1 0.5 0.11 12.6 0.5 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal GCN5L1 PF06320.13 GBG58889.1 - 0.044 13.9 4.0 0.11 12.6 4.0 1.7 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) V_ATPase_I PF01496.19 GBG58889.1 - 0.066 11.1 0.2 0.082 10.8 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.11 GBG58889.1 - 0.071 12.7 1.8 0.12 12.0 1.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2987 PF11205.8 GBG58889.1 - 0.11 12.5 0.5 0.59 10.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) SOAR PF16533.5 GBG58889.1 - 2.3 8.2 9.5 21 5.2 0.5 3.0 2 1 0 2 2 2 0 STIM1 Orai1-activating region ATG16 PF08614.11 GBG58889.1 - 2.5 8.3 9.0 1 9.5 4.5 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Pkinase PF00069.25 GBG58890.1 - 5.9e-67 225.8 0.0 7.3e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG58890.1 - 6.1e-30 104.4 0.0 8.6e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GBG58890.1 - 0.00015 21.2 0.3 0.00029 20.2 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GBG58890.1 - 0.00023 20.2 0.1 0.0004 19.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GBG58890.1 - 0.0017 17.8 0.0 0.04 13.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like RNA_pol_3_Rpc31 PF11705.8 GBG58891.1 - 0.032 14.5 8.4 0.031 14.5 8.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 GBG58891.1 - 0.041 13.2 14.2 0.049 12.9 14.2 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GBG58891.1 - 0.067 12.9 14.1 0.077 12.7 14.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG58891.1 - 0.078 11.2 3.5 0.068 11.4 3.5 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 GBG58891.1 - 0.16 12.0 3.6 0.27 11.3 3.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 GBG58891.1 - 0.19 9.8 15.2 0.23 9.5 15.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 GBG58891.1 - 0.23 10.6 18.2 0.25 10.4 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27_N PF17748.1 GBG58891.1 - 0.26 11.1 1.9 0.38 10.6 1.9 1.2 1 0 0 1 1 1 0 VID27 N-terminal region PPP4R2 PF09184.11 GBG58891.1 - 0.7 9.4 5.6 0.77 9.3 5.6 1.1 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 GBG58891.1 - 0.79 9.6 11.3 0.74 9.7 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 GBG58891.1 - 0.97 8.8 7.1 1 8.7 7.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG58891.1 - 2.2 6.4 6.5 2.6 6.2 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 GBG58891.1 - 6.6 6.6 8.7 7.6 6.4 8.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RT_RNaseH_2 PF17919.1 GBG58892.1 - 3e-32 110.6 0.0 6.2e-32 109.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58892.1 - 3.5e-30 104.4 0.1 6.8e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG58892.1 - 7.3e-18 64.9 0.0 2.6e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG58892.1 - 1.3e-11 44.4 0.1 2.7e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG58892.1 - 0.042 13.5 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Helo_like_N PF17111.5 GBG58893.1 - 0.028 13.8 0.2 0.063 12.6 0.2 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF4611 PF15387.6 GBG58893.1 - 9.2 6.6 19.6 1.6 9.0 5.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4611) PPR_long PF17177.4 GBG58894.1 - 3.6e-68 229.1 0.0 3.5e-54 183.4 0.0 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PRORP PF16953.5 GBG58894.1 - 1.9e-55 188.0 0.0 2.6e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Protein-only RNase P PPR_2 PF13041.6 GBG58894.1 - 5e-12 45.8 0.4 0.00047 20.3 0.0 4.1 2 1 2 4 4 4 2 PPR repeat family PPR_3 PF13812.6 GBG58894.1 - 4.3e-09 36.3 0.0 0.00012 22.1 0.0 3.9 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 GBG58894.1 - 2.5e-05 24.2 6.6 0.61 10.5 0.0 5.4 6 0 0 6 6 6 2 PPR repeat RNase_Zc3h12a PF11977.8 GBG58894.1 - 0.0092 15.8 0.0 0.025 14.4 0.0 1.6 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_1 PF12854.7 GBG58894.1 - 0.16 11.7 0.0 7.7 6.3 0.0 2.6 2 0 0 2 2 2 0 PPR repeat SAPS PF04499.15 GBG58895.1 - 0.025 13.4 11.9 0.026 13.3 11.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF974 PF06159.13 GBG58896.1 - 2.3e-50 171.7 0.0 3.1e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 GBG58896.1 - 0.034 13.6 0.1 0.19 11.1 0.1 2.2 3 0 0 3 3 3 0 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 GBG58896.1 - 0.056 13.6 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Pkinase_Tyr PF07714.17 GBG58899.1 - 1.6e-57 194.7 0.0 2.2e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG58899.1 - 4.5e-56 190.1 0.0 5.9e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG58899.1 - 0.00011 22.2 1.7 0.0077 16.2 0.3 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF433 PF04255.14 GBG58899.1 - 0.13 12.1 0.0 0.83 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Pkinase_Tyr PF07714.17 GBG58900.1 - 1.4e-57 195.0 0.0 1.8e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG58900.1 - 3.8e-56 190.4 0.0 5e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG58900.1 - 9.1e-05 22.5 1.7 0.0072 16.3 0.3 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF433 PF04255.14 GBG58900.1 - 0.12 12.3 0.0 0.78 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Ank_4 PF13637.6 GBG58901.1 - 8.4e-13 48.6 0.5 6.2e-07 29.8 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG58901.1 - 1.2e-09 38.2 0.2 2.8e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 GBG58901.1 - 5.9e-09 36.0 0.1 3.6e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 GBG58901.1 - 2.9e-08 34.2 0.1 5.6e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GBG58901.1 - 1.7e-07 31.0 0.1 1.8e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat gag-asp_proteas PF13975.6 GBG58902.1 - 9.2e-06 26.1 0.0 2.8e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG58902.1 - 0.00091 19.0 0.1 0.0018 18.1 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG58902.1 - 0.0014 19.3 0.0 0.0037 17.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG58902.1 - 0.021 14.5 0.3 0.039 13.6 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG58902.1 - 0.024 14.7 1.1 0.051 13.7 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 GBG58902.1 - 0.058 13.2 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Plavaka PF18759.1 GBG58903.1 - 4.4e-28 98.5 0.3 7.7e-28 97.7 0.3 1.3 1 0 0 1 1 1 1 Plavaka transposase Peptidase_C48 PF02902.19 GBG58903.1 - 1.3e-05 25.2 0.3 2.9e-05 24.0 0.3 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain rve PF00665.26 GBG58904.1 - 8.7e-09 35.6 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG58904.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain RVT_1 PF00078.27 GBG58906.1 - 3.9e-29 101.8 0.1 7.3e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58907.1 - 3.7e-10 39.7 0.0 6.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58907.1 - 4.4e-05 23.7 0.0 7.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2953 PF11167.8 GBG58907.1 - 0.029 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) SDA1 PF05285.12 GBG58907.1 - 0.2 11.0 16.0 0.24 10.8 16.0 1.1 1 0 0 1 1 1 0 SDA1 CPSF100_C PF13299.6 GBG58907.1 - 0.3 11.3 3.1 0.44 10.7 3.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BUD22 PF09073.10 GBG58907.1 - 0.48 9.7 21.1 0.64 9.3 21.1 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG58907.1 - 0.59 8.4 11.9 0.79 7.9 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG58907.1 - 0.63 8.2 17.1 0.77 7.9 17.1 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG58907.1 - 4.3 5.3 23.4 5.9 4.9 23.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Merozoite_SPAM PF07133.11 GBG58907.1 - 5 7.1 24.2 7.4 6.5 24.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Cwf_Cwc_15 PF04889.12 GBG58907.1 - 6.4 6.4 16.5 9.7 5.8 16.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Lin-8 PF03353.15 GBG58907.1 - 9.3 5.7 10.2 13 5.3 10.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RPA43_OB PF17875.1 GBG58908.1 - 0.25 12.0 6.0 0.44 11.2 6.0 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RVT_1 PF00078.27 GBG58909.1 - 0.00054 19.5 0.0 0.21 11.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_photolyase PF00875.18 GBG58909.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA photolyase MutS_V PF00488.21 GBG58910.1 - 2.3e-48 164.7 0.1 1.2e-47 162.4 0.1 2.0 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GBG58910.1 - 3.6e-26 92.6 0.0 8.2e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain III Myb_DNA-bind_4 PF13837.6 GBG58912.1 - 7.4e-07 29.5 2.1 7.4e-07 29.5 2.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG58913.1 - 2.7e-28 99.0 0.0 4.3e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG58913.1 - 1e-15 57.6 0.1 2.7e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG58913.1 - 3.8e-12 46.5 0.0 9.9e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG58913.1 - 1.8e-10 41.0 0.2 5.4e-10 39.5 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG58913.1 - 0.00041 20.5 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG58914.1 - 7.3e-29 100.9 0.4 3.8e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG58914.1 - 8.3e-05 22.8 0.0 0.00048 20.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG58914.1 - 0.005 17.4 0.1 0.011 16.3 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG58914.1 - 0.05 14.3 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG58914.1 - 0.38 11.0 5.0 0.43 10.9 0.1 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein DUF4187 PF13821.6 GBG58914.1 - 0.81 9.5 7.0 0.093 12.5 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) SDA1 PF05285.12 GBG58916.1 - 0.0022 17.5 37.4 0.0026 17.3 37.4 1.1 1 0 0 1 1 1 1 SDA1 SpoIIIAH PF12685.7 GBG58916.1 - 0.029 14.2 14.2 0.049 13.4 14.2 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein SID-1_RNA_chan PF13965.6 GBG58916.1 - 0.13 10.6 3.5 0.15 10.4 3.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Nop14 PF04147.12 GBG58916.1 - 0.23 9.6 39.5 0.3 9.3 39.5 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG58916.1 - 0.7 9.7 28.0 1.1 9.1 28.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4045 PF13254.6 GBG58916.1 - 0.92 9.1 19.8 1.3 8.6 19.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.16 GBG58916.1 - 1 9.4 5.0 1.3 9.1 5.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 GBG58916.1 - 1.3 7.7 19.0 1.6 7.4 19.0 1.1 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 GBG58916.1 - 2.2 7.1 17.8 2.9 6.7 17.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SAPS PF04499.15 GBG58916.1 - 3.4 6.4 16.5 4.1 6.1 16.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PA26 PF04636.13 GBG58916.1 - 4 6.2 10.2 5.3 5.9 10.2 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM60A PF15396.6 GBG58916.1 - 4.6 7.2 7.5 6.3 6.7 7.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF2828 PF11443.8 GBG58916.1 - 7.3 4.5 10.0 9.4 4.2 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Zip PF02535.22 GBG58916.1 - 7.8 5.6 13.5 9.7 5.3 13.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 GBG58916.1 - 8.6 5.0 16.3 11 4.7 16.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HLH PF00010.26 GBG58917.1 - 3.1e-10 39.8 0.1 5.9e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DNApol_Exo PF18136.1 GBG58917.1 - 0.053 12.7 0.7 0.087 12.0 0.7 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain RT_RNaseH_2 PF17919.1 GBG58918.1 - 7.4e-18 64.4 0.0 2.2e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58918.1 - 2.8e-17 62.9 0.0 5.1e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58919.1 - 5.4e-24 84.1 0.0 9.2e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58919.1 - 1.2e-20 73.7 0.0 2.9e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG58919.1 - 0.0035 17.9 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG58919.1 - 0.054 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease TAXi_N PF14543.6 GBG58921.1 - 2.4e-38 132.2 2.2 3.8e-38 131.5 2.2 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GBG58921.1 - 4.2e-18 65.8 0.7 9.6e-18 64.7 0.7 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GBG58922.1 - 9.4e-22 77.5 0.0 3.9e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp PF00026.23 GBG58922.1 - 2.4e-05 23.9 0.0 0.0027 17.2 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Pyridoxal_deC PF00282.19 GBG58923.1 - 2.7e-20 72.4 0.0 1.1e-19 70.4 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GBG58923.1 - 0.045 12.7 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V DUF4942 PF13708.6 GBG58923.1 - 0.19 11.7 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4942) Methyltransf_25 PF13649.6 GBG58924.1 - 6.6e-09 36.4 0.0 2.6e-06 28.1 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain DDE_Tnp_4 PF13359.6 GBG58924.1 - 8.6e-08 32.0 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_12 PF08242.12 GBG58924.1 - 1.6e-06 28.7 0.0 0.00014 22.5 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG58924.1 - 4.1e-06 26.7 0.0 0.02 14.7 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 GBG58924.1 - 0.00012 21.9 0.0 0.00047 20.0 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG58924.1 - 0.00023 21.8 0.0 0.0045 17.6 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GBG58924.1 - 0.00086 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TMEM51 PF15345.6 GBG58924.1 - 0.068 13.0 4.6 0.16 11.7 4.6 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 Plant_tran PF04827.14 GBG58924.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein MIase PF02426.16 GBG58924.1 - 0.16 12.1 0.1 0.96 9.6 0.0 2.3 2 0 0 2 2 2 0 Muconolactone delta-isomerase Dicty_REP PF05086.12 GBG58924.1 - 0.94 7.4 2.1 1.5 6.7 2.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.9 GBG58924.1 - 4.1 5.9 24.7 0.39 9.2 18.5 2.0 2 0 0 2 2 2 0 Macoilin family Mucin PF01456.17 GBG58924.1 - 4.7 7.2 19.3 14 5.7 19.3 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Myb_DNA-bind_4 PF13837.6 GBG58925.1 - 0.00012 22.4 0.9 0.0005 20.4 0.1 2.4 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain CLP_protease PF00574.23 GBG58926.1 - 2.6e-67 226.3 0.0 3.5e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Clp protease RVT_1 PF00078.27 GBG58926.1 - 4.5e-07 29.6 0.0 6.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG58928.1 - 6.5e-31 106.7 0.0 1.6e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58928.1 - 3.3e-28 97.7 0.0 6.8e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG58928.1 - 3e-15 56.4 0.0 7.9e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG58928.1 - 5.9e-07 29.2 0.0 9.6e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG58928.1 - 2e-06 27.8 0.1 4.6e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG58928.1 - 0.0005 20.2 0.1 0.0011 19.1 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Pkinase PF00069.25 GBG58929.1 - 2.2e-74 250.2 0.0 3e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG58929.1 - 5.8e-34 117.5 0.0 9e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG58929.1 - 1.2e-11 44.4 0.0 1.1e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like EF-hand_1 PF00036.32 GBG58929.1 - 1.1e-10 40.3 5.0 0.00013 21.2 0.5 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 GBG58929.1 - 2.6e-09 37.4 3.7 1.2e-06 28.9 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GBG58929.1 - 2.5e-08 33.6 2.7 6.5e-07 29.1 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG58929.1 - 2.9e-06 26.7 2.0 0.025 14.5 0.4 4.4 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 GBG58929.1 - 3.9e-05 22.9 2.8 0.0011 18.3 0.4 3.4 3 0 0 3 3 3 1 EF hand Kdo PF06293.14 GBG58929.1 - 8.5e-05 22.0 0.1 0.00021 20.7 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family S10_plectin PF03501.15 GBG58931.1 - 3.2e-47 158.5 0.8 2.7e-30 104.3 0.2 2.1 1 1 1 2 2 2 2 Plectin/S10 domain Cwf_Cwc_15 PF04889.12 GBG58931.1 - 0.0032 17.3 7.0 0.0039 17.0 7.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 GBG58931.1 - 0.0057 16.9 2.9 0.0089 16.3 2.9 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 GBG58931.1 - 0.0069 15.8 9.2 0.0098 15.3 9.2 1.2 1 0 0 1 1 1 1 NOA36 protein PBP1_TM PF14812.6 GBG58931.1 - 3 8.3 15.9 4.6 7.7 13.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF688 PF05097.12 GBG58931.1 - 4.8 6.3 5.7 6.2 5.9 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) AAA_18 PF13238.6 GBG58933.1 - 5.4e-27 94.9 0.0 9e-27 94.2 0.0 1.3 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 GBG58933.1 - 5.3e-07 30.1 0.0 3e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GBG58933.1 - 2e-05 24.9 0.1 0.00018 21.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 GBG58933.1 - 0.00012 22.2 0.0 0.0053 16.9 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA PF00004.29 GBG58933.1 - 0.00034 21.0 0.0 0.00098 19.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GBG58933.1 - 0.00067 19.8 0.0 0.29 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GBG58933.1 - 0.0013 19.1 0.0 0.0022 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 GBG58933.1 - 0.0016 18.4 0.2 0.6 9.9 0.1 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase Zeta_toxin PF06414.12 GBG58933.1 - 0.0045 16.3 0.1 0.029 13.7 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin SKI PF01202.22 GBG58933.1 - 0.0051 16.9 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase ATPase PF06745.13 GBG58933.1 - 0.018 14.4 0.3 0.045 13.1 0.1 1.7 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 GBG58933.1 - 0.033 14.6 0.1 0.085 13.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 GBG58933.1 - 0.043 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 GBG58933.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 GBG58933.1 - 0.082 12.6 0.4 0.15 11.7 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GBG58933.1 - 0.093 12.7 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GBG58933.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GBG58933.1 - 0.15 12.4 0.2 0.31 11.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 GBG58933.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NIF PF03031.18 GBG58934.1 - 2e-12 47.1 0.1 3.1e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.32 GBG58937.1 - 0.00013 22.6 11.8 0.062 14.2 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat RT_RNaseH_2 PF17919.1 GBG58938.1 - 1.2e-22 79.8 0.0 2.4e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58938.1 - 1.2e-19 70.5 0.0 2.2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG58938.1 - 1.9e-06 28.4 0.0 4.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58938.1 - 1e-05 26.0 0.0 1.9e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG58938.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG58938.1 - 0.001 19.2 0.0 0.0036 17.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG58938.1 - 0.0074 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease ST7 PF04184.12 GBG58938.1 - 0.23 9.9 0.0 0.35 9.3 0.0 1.2 1 0 0 1 1 1 0 ST7 protein B12D PF06522.11 GBG58939.1 - 4.8e-16 58.3 0.0 6.1e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RT_RNaseH_2 PF17919.1 GBG58940.1 - 2.8e-31 107.5 0.0 8.9e-17 61.0 0.0 2.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58940.1 - 2.9e-30 104.7 0.0 5e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58940.1 - 1.2e-12 47.8 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58941.1 - 2.1e-23 82.3 0.0 4.4e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58941.1 - 5.1e-22 78.2 0.0 9.1e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58941.1 - 4.8e-07 29.5 0.2 1.2e-06 28.2 0.2 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG58941.1 - 0.00034 20.8 0.0 0.0015 18.8 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG58941.1 - 0.00058 20.4 0.1 0.0027 18.2 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG58941.1 - 0.00059 20.4 0.0 0.0022 18.6 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG58941.1 - 0.25 11.2 0.1 0.63 9.8 0.0 1.6 2 0 0 2 2 2 0 Aspartyl protease DUF659 PF04937.15 GBG58942.1 - 9.5e-22 77.5 0.0 1.7e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG58942.1 - 0.0001 22.0 0.4 0.0001 22.0 0.4 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region TFIIA PF03153.13 GBG58942.1 - 0.0015 18.6 39.6 0.0015 18.6 39.6 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PPR_2 PF13041.6 GBG58943.1 - 8.3e-62 205.2 7.9 3.8e-12 46.2 0.0 15.0 11 3 6 17 17 17 10 PPR repeat family PPR PF01535.20 GBG58943.1 - 5.5e-55 179.9 19.6 2.2e-06 27.5 0.1 15.4 16 1 0 16 16 15 9 PPR repeat PPR_3 PF13812.6 GBG58943.1 - 6.4e-48 160.7 0.0 1.6e-11 44.1 0.0 9.0 7 2 1 9 9 9 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG58943.1 - 2e-41 139.4 10.0 3.9e-08 32.9 0.0 10.1 11 0 0 11 11 11 6 PPR repeat PPR_long PF17177.4 GBG58943.1 - 2.3e-36 125.2 0.0 8.5e-17 61.2 0.0 4.9 4 1 1 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GBG58943.1 - 2.1e-08 34.3 11.5 2.6 9.1 0.0 8.8 7 1 3 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 GBG58943.1 - 5.1e-06 26.9 1.1 2.8 8.5 0.1 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_5 PF12688.7 GBG58943.1 - 0.033 14.4 0.1 0.2 11.9 0.1 2.4 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_7 PF13176.6 GBG58943.1 - 0.034 14.2 0.0 9.6 6.5 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat ECSIT PF06239.11 GBG58943.1 - 0.047 12.8 0.0 26 3.8 0.0 4.1 2 1 2 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway MRP-S27 PF10037.9 GBG58943.1 - 0.051 12.4 0.0 19 4.0 0.0 3.1 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S27 CCDC53 PF10152.9 GBG58946.1 - 0.45 10.9 2.0 0.52 10.7 2.0 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PAP2 PF01569.21 GBG58947.1 - 0.00051 19.8 0.4 0.0013 18.5 0.4 1.7 1 0 0 1 1 1 1 PAP2 superfamily RVT_1 PF00078.27 GBG58948.1 - 6.5e-32 110.8 0.1 1.2e-31 110.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58948.1 - 9e-28 96.3 0.0 4.1e-27 94.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58948.1 - 2.6e-26 91.9 0.1 1.1e-25 90.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG58948.1 - 4.3e-05 23.3 0.0 9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG58948.1 - 0.00075 20.1 0.0 0.0018 18.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58948.1 - 0.012 16.2 0.0 0.1 13.2 0.0 2.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG58948.1 - 0.039 13.7 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF4392 PF14336.6 GBG58948.1 - 0.13 11.6 1.1 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Asp_protease PF09668.10 GBG58948.1 - 0.19 11.5 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-NF-X1 PF01422.17 GBG58949.1 - 5.1e-15 55.2 184.8 2.2e-05 24.4 17.6 10.9 10 0 0 10 10 10 6 NF-X1 type zinc finger R3H PF01424.22 GBG58949.1 - 7.1e-08 32.3 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain MAJIN PF15077.6 GBG58949.1 - 1.8 8.3 11.9 4.5 7.0 11.9 1.6 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF1980 PF09323.10 GBG58950.1 - 0.00013 21.9 0.8 0.00024 21.1 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) NB-ARC PF00931.22 GBG58950.1 - 0.0017 17.6 0.0 0.0017 17.6 0.0 2.1 2 0 0 2 2 1 1 NB-ARC domain TraT PF05818.12 GBG58950.1 - 0.002 17.9 5.3 0.002 17.9 5.3 1.9 2 0 0 2 2 2 1 Enterobacterial TraT complement resistance protein Presenilin PF01080.17 GBG58950.1 - 0.0041 15.9 6.4 0.0058 15.5 6.4 1.2 1 0 0 1 1 1 1 Presenilin ABC_tran PF00005.27 GBG58950.1 - 0.0071 16.9 0.2 0.0071 16.9 0.2 2.6 2 0 0 2 2 2 1 ABC transporter RskA PF10099.9 GBG58950.1 - 0.017 15.4 2.9 0.017 15.4 2.9 1.7 2 0 0 2 2 1 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 GBG58950.1 - 0.023 14.8 2.3 0.042 13.9 2.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dynamin_N PF00350.23 GBG58950.1 - 0.04 14.0 5.0 4.1 7.4 2.9 2.3 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.23 GBG58950.1 - 0.054 13.6 0.2 0.14 12.3 0.2 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase EOS1 PF12326.8 GBG58950.1 - 0.068 13.1 0.5 0.1 12.6 0.5 1.3 1 0 0 1 1 1 0 N-glycosylation protein TERB2 PF15101.6 GBG58950.1 - 0.091 12.8 16.8 0.68 9.9 18.5 1.5 2 0 0 2 2 1 0 Telomere-associated protein TERB2 FeoB_N PF02421.18 GBG58950.1 - 0.095 12.2 0.2 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Orf78 PF06024.12 GBG58950.1 - 0.11 12.8 6.6 0.25 11.7 6.6 1.5 1 0 0 1 1 1 0 Orf78 (ac78) GNAT_acetyltr_2 PF13718.6 GBG58950.1 - 0.11 11.9 4.8 1.2 8.5 6.0 1.9 2 0 0 2 2 2 0 GNAT acetyltransferase 2 SpoIIP PF07454.11 GBG58950.1 - 0.12 11.8 11.1 0.18 11.2 11.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 GBG58950.1 - 0.16 10.2 20.4 0.22 9.7 20.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 GBG58950.1 - 0.18 11.4 41.8 0.34 10.5 41.8 1.3 1 0 0 1 1 1 0 Spt20 family SID-1_RNA_chan PF13965.6 GBG58950.1 - 0.22 9.9 0.3 0.29 9.5 0.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ctr PF04145.15 GBG58950.1 - 0.23 12.1 4.1 0.46 11.1 4.1 1.5 1 0 0 1 1 1 0 Ctr copper transporter family RR_TM4-6 PF06459.12 GBG58950.1 - 0.35 10.7 9.2 0.6 9.9 9.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 GBG58950.1 - 0.45 10.7 9.5 0.072 13.3 5.5 1.6 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal eIF-3_zeta PF05091.12 GBG58950.1 - 0.53 9.2 17.8 0.8 8.6 17.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EPL1 PF10513.9 GBG58950.1 - 0.55 10.6 11.8 1 9.8 11.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Gti1_Pac2 PF09729.9 GBG58950.1 - 0.6 10.2 9.0 1.1 9.3 9.0 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family OATP PF03137.20 GBG58950.1 - 0.98 7.6 6.0 1.5 7.0 6.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Suf PF05843.14 GBG58950.1 - 0.98 9.3 16.3 1.8 8.5 16.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 GBG58950.1 - 1.1 9.2 36.4 0.29 11.1 33.2 1.5 2 0 0 2 2 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 GBG58950.1 - 1.2 9.8 24.4 0.2 12.3 18.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EIIBC-GUT_N PF03612.14 GBG58950.1 - 1.2 8.8 10.3 2 8.1 10.3 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Membralin PF09746.9 GBG58950.1 - 1.4 7.9 5.5 2.1 7.3 5.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein FAM60A PF15396.6 GBG58950.1 - 1.4 8.9 6.8 2.4 8.1 6.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 GBG58950.1 - 1.9 7.5 9.4 3.1 6.8 9.4 1.2 1 0 0 1 1 1 0 CLN3 protein TMEM51 PF15345.6 GBG58950.1 - 1.9 8.3 15.2 3.3 7.5 15.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 AAA_23 PF13476.6 GBG58950.1 - 2.1 8.8 18.9 3 8.3 11.8 2.3 2 0 0 2 2 2 0 AAA domain Band_3_cyto PF07565.13 GBG58950.1 - 2.3 8.0 11.6 4.1 7.1 11.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4175 PF13779.6 GBG58950.1 - 2.4 6.0 33.0 3.5 5.4 33.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF702 PF05142.12 GBG58950.1 - 2.6 8.5 13.5 5 7.6 13.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Connexin PF00029.19 GBG58950.1 - 3.3 7.4 9.9 5.8 6.6 9.9 1.3 1 0 0 1 1 1 0 Connexin DUF2722 PF10846.8 GBG58950.1 - 4.7 6.0 35.4 8.2 5.2 35.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Plasmodium_Vir PF05795.11 GBG58950.1 - 6.1 6.2 5.7 9.5 5.5 5.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PepSY_TM PF03929.16 GBG58950.1 - 6.3 6.4 7.0 13 5.3 7.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM region AIF_C PF14721.6 GBG58950.1 - 6.5 7.1 9.4 13 6.2 9.4 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM176 PF14851.6 GBG58950.1 - 6.6 6.4 9.2 12 5.6 9.2 1.3 1 0 0 1 1 1 0 FAM176 family FHIPEP PF00771.20 GBG58950.1 - 6.9 5.0 9.5 4 5.8 7.5 1.5 2 0 0 2 2 2 0 FHIPEP family MeaB PF03308.16 GBG58950.1 - 7.4 5.5 10.0 0.14 11.1 0.2 2.3 2 0 0 2 2 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 GBG58950.1 - 9.6 6.1 7.8 1.5 8.7 0.0 2.3 2 0 0 2 2 1 0 RsgA GTPase KH_1 PF00013.29 GBG58951.1 - 2.4e-34 117.0 5.6 4.1e-17 61.8 0.5 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 GBG58951.1 - 2.6e-07 30.4 3.6 0.0021 17.8 0.2 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 GBG58951.1 - 5.9e-07 29.3 2.7 0.024 14.5 0.1 2.5 2 0 0 2 2 2 2 KH domain KH_1 PF00013.29 GBG58952.1 - 2.4e-34 117.0 5.6 4e-17 61.8 0.5 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 GBG58952.1 - 2.7e-07 30.3 3.7 0.0021 17.8 0.2 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 GBG58952.1 - 3.9e-07 29.9 3.0 0.015 15.2 0.4 2.5 2 0 0 2 2 2 2 KH domain DDE_Tnp_4 PF13359.6 GBG58953.1 - 6e-26 91.0 0.0 1.3e-25 89.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG58953.1 - 3.3e-13 49.7 0.0 4.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG58953.1 - 1.1e-05 25.2 0.2 0.00023 20.9 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG58953.1 - 0.029 14.7 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG58955.1 - 6.7e-10 39.2 4.7 2.5e-08 34.2 2.2 2.4 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG58955.1 - 0.003 17.9 4.2 0.011 16.1 1.8 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Hep_59 PF07052.11 GBG58956.1 - 0.021 15.5 10.6 0.038 14.8 9.9 1.8 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Transglut_core3 PF13471.6 GBG58956.1 - 0.27 11.1 0.1 0.27 11.1 0.1 2.9 2 1 2 4 4 4 0 Transglutaminase-like superfamily Histone PF00125.24 GBG58957.1 - 4.6e-19 69.1 0.4 1.4e-18 67.5 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 RT_RNaseH_2 PF17919.1 GBG58959.1 - 2.9e-33 113.9 0.0 6.6e-33 112.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58959.1 - 7.4e-30 103.3 0.1 1.8e-29 102.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58959.1 - 2.5e-12 46.8 0.2 5.7e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG58959.1 - 2.5e-08 33.6 3.6 2.5e-08 33.6 3.6 2.2 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG58959.1 - 0.021 14.6 0.7 0.07 13.0 0.7 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG58959.1 - 0.21 11.4 6.1 0.037 13.8 2.2 1.7 2 0 0 2 2 2 0 Zinc knuckle hDGE_amylase PF14701.6 GBG58959.1 - 5.5 6.0 8.8 12 4.8 8.8 1.5 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Fer2 PF00111.27 GBG58960.1 - 5.4e-12 45.5 0.1 1.2e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RVT_1 PF00078.27 GBG58961.1 - 3.1e-34 118.4 0.1 5.4e-34 117.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Putative_PNPOx PF01243.20 GBG58961.1 - 3.1e-25 88.2 0.0 7.8e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 GBG58961.1 - 1.3e-11 44.3 0.4 5e-11 42.5 0.4 2.0 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 GBG58961.1 - 5e-08 33.5 0.2 2.3e-06 28.1 0.0 2.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 GBG58961.1 - 0.0055 16.3 0.1 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase like CENP-F_leu_zip PF10473.9 GBG58962.1 - 0.0092 16.0 0.4 0.0092 16.0 0.4 2.4 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 GBG58962.1 - 0.17 12.3 14.1 0.62 10.5 5.8 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Endonuc-dimeris PF09124.10 GBG58962.1 - 0.17 12.0 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation Golgin_A5 PF09787.9 GBG58962.1 - 0.37 10.2 8.8 0.2 11.1 4.0 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 PRKG1_interact PF15898.5 GBG58962.1 - 1.9 9.4 10.9 4 8.4 5.7 2.6 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 GBG58962.1 - 3.3 8.1 10.0 0.93 9.9 2.1 2.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) APG6_N PF17675.1 GBG58962.1 - 4.7 7.8 16.0 1.8 9.1 0.7 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 GBG58962.1 - 4.8 6.5 11.8 0.62 9.4 3.6 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding YjeF_N PF03853.15 GBG58963.1 - 1.2e-29 103.4 0.0 1.5e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus adh_short PF00106.25 GBG58964.1 - 3.8e-25 88.5 0.0 3.7e-22 78.7 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GBG58964.1 - 1.5e-13 50.9 0.0 4.3e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG58964.1 - 8.8e-05 22.5 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GBG58964.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GBG58964.1 - 0.29 11.0 0.8 0.42 10.5 0.2 1.5 2 0 0 2 2 2 0 NAD(P)H-binding Pox_A_type_inc PF04508.12 GBG58965.1 - 0.096 12.6 6.0 2.6 8.0 0.0 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF4515 PF14988.6 GBG58965.1 - 9 6.1 18.0 3.7 7.3 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4515) PAXIP1_C PF15364.6 GBG58966.1 - 0.048 14.0 7.8 0.065 13.6 7.8 1.1 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Nop14 PF04147.12 GBG58966.1 - 0.43 8.7 14.9 0.42 8.8 14.9 1.0 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.12 GBG58966.1 - 0.51 9.2 10.0 0.6 9.0 10.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Merozoite_SPAM PF07133.11 GBG58966.1 - 1.5 8.8 25.2 1.8 8.5 25.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DNA_pol_phi PF04931.13 GBG58966.1 - 3.6 5.6 16.1 4.1 5.4 16.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi MIS13 PF08202.11 GBG58966.1 - 4.9 6.4 11.7 5.9 6.1 11.7 1.0 1 0 0 1 1 1 0 Mis12-Mtw1 protein family TRAP_alpha PF03896.16 GBG58966.1 - 5.2 6.2 9.7 6.2 5.9 9.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4637 PF15470.6 GBG58966.1 - 6.9 6.4 12.9 9.4 5.9 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) zf-CCHC PF00098.23 GBG58967.1 - 0.0035 17.3 1.0 0.0035 17.3 1.0 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG58967.1 - 0.069 13.0 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle TMEM171 PF15471.6 GBG58967.1 - 1.1 8.2 2.8 0.44 9.5 0.4 1.5 2 0 0 2 2 2 0 Transmembrane protein family 171 FPN1 PF06963.12 GBG58968.1 - 1.3e-13 50.4 0.1 1.9e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) rve PF00665.26 GBG58968.1 - 0.13 12.5 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain FPN1 PF06963.12 GBG58969.1 - 4.9e-07 28.7 0.1 7.1e-07 28.1 0.1 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) rve PF00665.26 GBG58969.1 - 0.067 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG58970.1 - 0.00061 20.0 1.9 0.00086 19.5 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG58970.1 - 0.013 16.1 0.3 0.046 14.3 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG58970.1 - 0.048 14.3 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.12 GBG58970.1 - 2 9.1 7.1 0.6 10.8 0.5 2.8 3 0 0 3 3 3 0 SlyX RT_RNaseH PF17917.1 GBG58972.1 - 5.4e-31 107.0 0.1 2e-30 105.2 0.1 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58972.1 - 2.9e-30 104.2 0.0 1.3e-29 102.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG58972.1 - 5.9e-16 58.7 0.1 4.4e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG58972.1 - 1.4e-08 34.5 0.0 2.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG58972.1 - 1.7e-06 28.6 0.0 4.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG58972.1 - 0.00015 22.2 0.0 0.00071 20.1 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG58972.1 - 0.0025 17.6 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG58972.1 - 0.0039 17.0 0.0 0.32 10.8 0.0 2.5 2 1 0 2 2 2 1 Aspartyl protease Phage_GPO PF05929.11 GBG58972.1 - 0.17 11.5 0.1 0.17 11.5 0.1 3.2 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase FPN1 PF06963.12 GBG58973.1 - 2.9e-54 184.3 7.9 3.3e-54 184.1 7.9 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Flavi_NS4A PF01350.17 GBG58973.1 - 1.8 8.5 4.9 0.76 9.7 0.6 2.1 1 1 1 2 2 2 0 Flavivirus non-structural protein NS4A Phage_integrase PF00589.22 GBG58974.1 - 2.5e-08 33.9 0.0 4.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Mpp10 PF04006.12 GBG58974.1 - 0.2 10.1 11.6 0.29 9.5 11.6 1.2 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG58974.1 - 0.28 10.6 12.9 0.41 10.0 12.9 1.2 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG58974.1 - 0.3 11.3 12.6 0.46 10.7 12.6 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG58974.1 - 1.1 7.4 15.2 1.4 7.0 15.2 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG58974.1 - 1.8 7.8 12.5 3.2 7.0 12.5 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG58974.1 - 2.4 6.4 8.7 3.3 5.9 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 GBG58974.1 - 5.4 6.1 17.0 9.5 5.2 17.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 GBG58974.1 - 9.4 4.6 5.0 14 4.1 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4411 PF14367.6 GBG58975.1 - 0.22 11.4 3.2 0.28 11.1 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) COX16 PF14138.6 GBG58975.1 - 0.35 11.4 7.3 0.52 10.9 7.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Pkinase_Tyr PF07714.17 GBG58977.1 - 5e-28 98.1 0.0 7.8e-28 97.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG58977.1 - 2.5e-26 92.6 0.0 3.3e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pro_CA PF00484.19 GBG58978.1 - 2.3e-44 151.5 0.0 4.2e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Carbonic anhydrase HA2 PF04408.23 GBG58980.1 - 4.8e-22 78.3 0.0 4.8e-22 78.3 0.0 3.7 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GBG58980.1 - 1.9e-19 69.8 0.1 3.8e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GBG58980.1 - 4.9e-13 49.4 0.0 1.1e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 GBG58980.1 - 4.3e-05 23.3 0.0 0.00013 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GBG58980.1 - 6.1e-05 23.3 0.0 0.00019 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 GBG58980.1 - 0.00037 20.3 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 GBG58980.1 - 0.0011 18.2 0.0 0.0067 15.5 0.0 2.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_19 PF13245.6 GBG58980.1 - 0.0012 19.2 0.0 0.0031 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 GBG58980.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 GBG58980.1 - 0.081 13.4 0.0 0.35 11.4 0.0 2.1 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 GBG58980.1 - 0.14 11.7 0.1 0.39 10.3 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 GBG58980.1 - 0.24 11.9 0.0 0.24 11.9 0.0 3.5 2 2 0 2 2 1 0 AAA domain RVT_1 PF00078.27 GBG58981.1 - 2.2e-33 115.7 0.1 4.6e-33 114.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG58981.1 - 1.4e-30 105.2 0.0 3.3e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG58981.1 - 4.6e-26 91.2 0.0 8.4e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG58981.1 - 1.6e-13 50.5 0.1 3.9e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG58981.1 - 0.0089 16.2 0.0 0.081 13.2 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG58982.1 - 3.3e-06 27.4 0.5 6.9e-06 26.4 0.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG58982.1 - 0.016 15.4 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG58982.1 - 0.038 14.2 0.1 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG58982.1 - 0.045 14.1 0.4 0.091 13.1 0.4 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Dimer_Tnp_hAT PF05699.14 GBG58983.1 - 0.00077 19.2 0.3 0.0013 18.4 0.3 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DEK_C PF08766.11 GBG58985.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 DEK C terminal domain Peptidase_C14 PF00656.22 GBG58987.1 - 7e-28 98.2 0.2 1.9e-27 96.8 0.0 1.8 2 0 0 2 2 2 1 Caspase domain Myb_DNA-bind_4 PF13837.6 GBG58988.1 - 7.8e-09 35.8 1.3 1.8e-08 34.6 1.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG58988.1 - 0.13 12.6 0.6 0.27 11.6 0.6 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG58989.1 - 2.4e-23 82.5 0.0 6.7e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG58989.1 - 3e-06 27.0 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein KASH_CCD PF14662.6 GBG58990.1 - 0.0089 15.9 7.0 0.016 15.1 6.1 1.8 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH YscK PF06578.12 GBG58990.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 YOP proteins translocation protein K (YscK) TSC22 PF01166.18 GBG58990.1 - 0.24 11.8 5.9 3.6 8.0 0.2 3.9 2 1 2 4 4 4 0 TSC-22/dip/bun family Cnn_1N PF07989.11 GBG58990.1 - 0.33 11.1 7.1 1.1 9.4 2.1 3.0 2 2 0 2 2 2 0 Centrosomin N-terminal motif 1 Cep57_CLD_2 PF14197.6 GBG58990.1 - 0.94 9.6 6.9 0.75 9.9 1.3 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Peptidase_M24 PF00557.24 GBG58992.1 - 2.2e-26 92.9 0.2 3e-26 92.4 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.24 GBG58993.1 - 2.2e-26 92.9 0.2 2.9e-26 92.4 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_hydro_28 PF00295.17 GBG58994.1 - 1.4e-64 218.2 0.1 2.1e-64 217.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 GBG58994.1 - 0.00058 19.7 7.1 0.001 18.9 7.1 1.5 1 0 0 1 1 1 1 Right handed beta helix region RT_RNaseH PF17917.1 GBG58995.1 - 2.2e-21 76.1 0.0 3.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG58995.1 - 2.4e-19 69.2 0.0 5.2e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SICA_C PF12879.7 GBG58995.1 - 0.14 12.2 1.8 0.38 10.8 1.8 1.7 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain gag-asp_proteas PF13975.6 GBG58996.1 - 5.2e-10 39.8 0.0 1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG58996.1 - 1.1e-06 29.1 0.0 2.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG58996.1 - 2.3e-05 24.2 0.4 3.9e-05 23.4 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG58996.1 - 0.0014 18.9 0.0 0.0044 17.3 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease RXLR PF16810.5 GBG58996.1 - 0.17 12.3 4.7 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Nop14 PF04147.12 GBG58997.1 - 0.016 13.5 6.2 0.023 12.9 6.2 1.3 1 0 0 1 1 1 0 Nop14-like family DUF755 PF05501.11 GBG58998.1 - 2.1 8.6 6.9 4.4 7.6 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF659 PF04937.15 GBG58999.1 - 2.3e-32 111.9 0.1 4.5e-32 111.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) EccE PF11203.8 GBG58999.1 - 0.63 10.4 3.2 1.2 9.5 0.0 2.9 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE GCV_T PF01571.21 GBG59000.1 - 8.5e-26 90.9 0.1 1.1e-25 90.5 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 GBG59000.1 - 8.2e-20 70.5 0.0 1.4e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain RT_RNaseH_2 PF17919.1 GBG59001.1 - 4.4e-27 94.0 0.0 1e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59001.1 - 5.8e-24 84.4 0.0 1.1e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59001.1 - 3.2e-07 30.1 0.0 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG59001.1 - 0.024 14.5 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) DUF3807 PF12720.7 GBG59001.1 - 0.35 11.1 14.5 0.57 10.4 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SDA1 PF05285.12 GBG59001.1 - 0.91 8.9 24.6 1.3 8.3 24.6 1.1 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG59002.1 - 2.5e-29 102.4 0.1 4.3e-29 101.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59002.1 - 3.3e-09 36.7 0.0 5.3e-08 32.8 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59002.1 - 0.00053 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59002.1 - 0.019 15.6 0.0 0.04 14.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG59002.1 - 0.073 13.6 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease APG17 PF04108.12 GBG59002.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH PF17917.1 GBG59002.1 - 0.18 12.1 0.0 0.62 10.4 0.0 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Cellulase PF00150.18 GBG59003.1 - 1.8e-09 37.4 0.6 2.5e-09 37.0 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pentapeptide_2 PF01469.18 GBG59004.1 - 0.055 13.4 2.4 0.12 12.3 2.4 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Nop14 PF04147.12 GBG59004.1 - 0.62 8.2 18.6 0.84 7.8 18.6 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG59004.1 - 4.8 6.4 19.4 5.6 6.2 19.4 1.0 1 0 0 1 1 1 0 BUD22 DUF659 PF04937.15 GBG59005.1 - 9.2e-12 45.1 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Drf_FH1 PF06346.12 GBG59008.1 - 2.8 7.7 53.3 6.4 6.5 32.4 2.2 1 1 1 2 2 2 0 Formin Homology Region 1 RVT_1 PF00078.27 GBG59009.1 - 1.9e-31 109.3 0.0 2.9e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG59009.1 - 0.0083 16.7 0.0 0.036 14.7 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG59010.1 - 2.6e-05 24.5 2.0 4.3e-05 23.8 2.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG59010.1 - 0.0012 18.9 0.3 0.0031 17.6 0.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 GBG59011.1 - 0.00073 19.8 0.7 0.012 15.9 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein SAPS PF04499.15 GBG59011.1 - 0.071 11.9 5.8 0.085 11.6 5.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein VIR_N PF15912.5 GBG59011.1 - 0.2 11.3 15.6 0.4 10.2 15.6 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 GBG59011.1 - 0.71 9.9 3.1 1.1 9.3 3.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop14 PF04147.12 GBG59011.1 - 4 5.5 36.0 5.2 5.1 36.0 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG59012.1 - 5.9e-29 101.2 0.0 9.9e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59012.1 - 2.6e-16 59.5 0.0 1.5e-11 44.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG59012.1 - 7.7e-12 44.9 0.1 5.1e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.14 GBG59012.1 - 2.1e-09 37.0 0.1 5.2e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH PF17917.1 GBG59012.1 - 2.6e-05 24.4 0.0 9.3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG59013.1 - 9.6e-32 109.9 0.1 1.4e-31 109.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4187 PF13821.6 GBG59014.1 - 0.0011 18.7 0.6 0.0031 17.3 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG59014.1 - 0.0019 18.5 2.6 0.0023 18.2 0.2 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG59014.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_C14 PF00656.22 GBG59015.1 - 2e-54 185.2 0.0 3.2e-54 184.5 0.0 1.3 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 GBG59015.1 - 0.005 16.8 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain HsdM_N PF12161.8 GBG59016.1 - 0.038 14.6 0.2 0.045 14.4 0.2 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain HBS1_N PF08938.10 GBG59016.1 - 0.28 11.5 4.6 0.45 10.8 4.6 1.4 1 0 0 1 1 1 0 HBS1 N-terminus TFCD_C PF12612.8 GBG59017.1 - 2e-37 128.9 0.0 5.8e-37 127.4 0.0 1.8 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.6 GBG59017.1 - 1.2e-05 25.6 5.3 0.14 12.7 0.1 4.7 5 0 0 5 5 5 2 HEAT-like repeat HEAT_PBS PF03130.16 GBG59017.1 - 0.00077 19.9 2.5 2.5 9.0 0.0 5.0 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT_2 PF13646.6 GBG59017.1 - 0.0051 17.2 1.8 4.9 7.6 0.2 4.1 4 0 0 4 4 4 2 HEAT repeats eRF1_1 PF03463.15 GBG59018.1 - 4.1e-51 172.3 0.0 6.5e-51 171.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 GBG59018.1 - 1.7e-28 99.5 0.0 2.8e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GBG59018.1 - 7e-26 90.9 0.2 2.1e-25 89.4 0.1 1.9 2 0 0 2 2 2 1 eRF1 domain 3 EF_TS PF00889.19 GBG59019.1 - 1.6e-56 191.2 0.4 2.3e-56 190.7 0.4 1.2 1 0 0 1 1 1 1 Elongation factor TS DUF1907 PF08925.11 GBG59019.1 - 0.092 12.2 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1907) Csm2_III-A PF03750.13 GBG59019.1 - 0.16 12.9 0.2 0.32 11.9 0.2 1.5 1 0 0 1 1 1 0 Csm2 Type III-A DUF3450 PF11932.8 GBG59020.1 - 0.69 9.2 10.3 1.1 8.4 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4355 PF14265.6 GBG59020.1 - 3.5 7.9 22.1 7.9 6.7 22.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF2828 PF11443.8 GBG59020.1 - 5.6 4.9 10.3 8.7 4.3 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) YolD PF08863.10 GBG59020.1 - 8.8 6.5 13.4 0.77 9.9 4.4 2.5 1 1 1 2 2 2 0 YolD-like protein Myb_DNA-bind_4 PF13837.6 GBG59021.1 - 9.6e-10 38.7 1.8 2.5e-09 37.4 1.8 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG59021.1 - 0.00042 20.3 0.3 0.00086 19.3 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG59021.1 - 0.0031 17.8 2.1 0.009 16.3 0.9 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG59021.1 - 0.019 15.2 0.4 0.039 14.1 0.4 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG59022.1 - 6e-20 71.5 0.0 2.7e-19 69.4 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG59022.1 - 9.8e-12 44.9 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG59022.1 - 0.0031 17.2 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain PIP49_C PF12260.8 GBG59022.1 - 0.0046 16.6 0.1 0.53 9.9 0.0 2.4 2 0 0 2 2 2 2 Protein-kinase domain of FAM69 RVT_1 PF00078.27 GBG59023.1 - 4.8e-19 68.8 0.1 8.6e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dynamin_N PF00350.23 GBG59024.1 - 2.4e-13 50.5 0.0 5.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_N PF00350.23 GBG59025.1 - 2.3e-13 50.5 0.0 5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family CBS PF00571.28 GBG59027.1 - 1.2e-18 67.2 4.3 5.2e-07 30.0 0.2 5.4 5 2 0 5 5 5 4 CBS domain zf-CCHC PF00098.23 GBG59028.1 - 0.00047 20.1 1.1 0.00047 20.1 1.1 1.9 2 0 0 2 2 2 1 Zinc knuckle DUF572 PF04502.13 GBG59028.1 - 0.026 14.2 15.6 0.032 13.9 15.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-CCHC_5 PF14787.6 GBG59028.1 - 0.044 13.5 0.5 0.1 12.4 0.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG59028.1 - 0.066 13.1 0.5 0.11 12.3 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Spem1 PF15670.5 GBG59029.1 - 0.07 12.7 2.7 0.1 12.2 2.7 1.4 1 1 0 1 1 1 0 Spermatid maturation protein 1 Snf7 PF03357.21 GBG59029.1 - 1.5 8.4 27.2 0.3 10.7 1.3 2.7 3 0 0 3 3 3 0 Snf7 Alb1 PF09135.11 GBG59029.1 - 9.1 7.2 18.3 1.7 9.6 11.2 2.4 2 0 0 2 2 2 0 Alb1 Beta_helix PF13229.6 GBG59030.1 - 1.2e-05 25.2 6.0 0.0024 17.7 6.0 3.0 1 1 0 1 1 1 1 Right handed beta helix region DUF1283 PF06932.11 GBG59030.1 - 0.55 10.5 5.8 1.3 9.3 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) rve PF00665.26 GBG59031.1 - 1.8e-11 44.2 0.0 7.2e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG59031.1 - 0.00017 22.1 0.2 0.00059 20.3 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG59031.1 - 0.015 15.6 1.0 0.015 15.6 1.0 2.9 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Asp_protease_2 PF13650.6 GBG59031.1 - 0.033 14.8 0.0 0.11 13.1 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG59031.1 - 0.086 12.6 0.9 0.17 11.7 0.9 1.4 1 0 0 1 1 1 0 Aspartyl protease CAS_CSE1 PF03378.15 GBG59032.1 - 0.21 10.0 0.0 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Hamartin PF04388.12 GBG59032.1 - 9.6 4.7 13.2 19 3.8 13.2 1.4 1 0 0 1 1 1 0 Hamartin protein Bac_rhodopsin PF01036.18 GBG59033.1 - 0.023 14.3 8.8 1.1 8.8 0.1 2.2 1 1 1 2 2 2 0 Bacteriorhodopsin-like protein EI24 PF07264.11 GBG59033.1 - 0.24 11.6 10.0 7 6.9 10.0 2.1 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Trep_Strep PF09605.10 GBG59034.1 - 0.0018 18.3 8.5 0.0026 17.8 8.5 1.3 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) Bac_rhodopsin PF01036.18 GBG59034.1 - 0.026 14.1 8.0 1.2 8.6 0.1 2.2 1 1 1 2 2 2 0 Bacteriorhodopsin-like protein EI24 PF07264.11 GBG59034.1 - 0.34 11.1 9.1 6.9 6.9 9.1 2.2 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) SRTM1 PF15872.5 GBG59034.1 - 2.1 8.5 4.0 1 9.5 0.4 2.0 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 RVT_1 PF00078.27 GBG59035.1 - 5.8e-27 94.6 0.5 1e-26 93.8 0.5 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CoA_binding_3 PF13727.6 GBG59036.1 - 0.014 15.4 0.6 0.037 14.0 0.6 1.6 1 0 0 1 1 1 0 CoA-binding domain WDCP PF15390.6 GBG59036.1 - 0.83 8.0 4.0 1.4 7.2 4.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SNF2_N PF00176.23 GBG59037.1 - 4.6e-62 209.8 0.2 8.2e-62 208.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 GBG59037.1 - 6.1e-45 152.9 16.5 6.1e-45 152.9 16.5 2.1 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 GBG59037.1 - 4.3e-17 62.5 0.0 9.2e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG59037.1 - 2.1e-05 24.6 0.0 6.5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG59037.1 - 0.001 18.9 0.0 0.0047 16.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase MlaE PF02405.16 GBG59038.1 - 2e-69 233.5 17.5 2.9e-69 233.0 17.5 1.2 1 0 0 1 1 1 1 Permease MlaE GRP PF07172.11 GBG59039.1 - 0.48 11.2 23.7 2.3 9.0 23.7 2.2 1 0 0 1 1 1 0 Glycine rich protein family HsbA PF12296.8 GBG59039.1 - 5.7 7.4 10.4 2.4 8.6 2.4 3.7 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Fib_alpha PF08702.10 GBG59040.1 - 0.16 12.2 3.5 0.57 10.4 0.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 GBG59040.1 - 5.7 6.7 6.1 8.5 6.1 5.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4611 PF15387.6 GBG59041.1 - 2.7 8.3 8.8 0.14 12.4 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF4504 PF14953.6 GBG59042.1 - 1.5e-07 31.1 0.0 1.1e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4504) Methyltransf_11 PF08241.12 GBG59043.1 - 1.2e-15 57.9 0.1 6.1e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG59043.1 - 1.6e-11 44.7 0.0 1.3e-07 32.2 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 GBG59043.1 - 1.1e-05 24.9 0.1 0.0007 19.0 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GBG59043.1 - 2.4e-05 24.1 0.0 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG59043.1 - 0.00018 21.4 0.0 0.00039 20.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 GBG59043.1 - 0.00048 18.8 1.4 0.035 12.7 0.1 2.6 2 1 1 3 3 3 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 GBG59043.1 - 0.00073 20.2 0.0 0.0073 17.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 GBG59043.1 - 0.02 14.7 0.1 0.66 9.8 0.0 2.5 2 1 0 2 2 2 0 Hypothetical methyltransferase UPF0020 PF01170.18 GBG59043.1 - 0.13 12.0 0.0 0.45 10.2 0.0 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 AviRa PF11599.8 GBG59043.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.4 1 1 0 1 1 1 0 RRNA methyltransferase AviRa CrgA PF06781.12 GBG59043.1 - 4.3 7.5 6.0 9.2 6.4 6.0 1.6 1 0 0 1 1 1 0 Cell division protein CrgA Glyco_tran_28_C PF04101.16 GBG59044.1 - 3.9e-23 82.3 0.0 1.2e-21 77.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Ribosomal_60s PF00428.19 GBG59044.1 - 0.0031 18.1 0.0 0.0065 17.0 0.0 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein CKAP2_C PF15297.6 GBG59044.1 - 0.0033 16.6 0.1 0.0042 16.2 0.1 1.1 1 0 0 1 1 1 1 Cytoskeleton-associated protein 2 C-terminus RPA43_OB PF17875.1 GBG59044.1 - 0.017 15.7 0.4 0.026 15.2 0.4 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I AF2331-like PF14556.6 GBG59044.1 - 0.03 14.9 0.1 0.08 13.5 0.0 1.7 2 0 0 2 2 2 0 AF2331-like FAM163 PF15069.6 GBG59044.1 - 0.075 13.5 0.5 0.17 12.3 0.5 1.6 1 0 0 1 1 1 0 FAM163 family Presenilin PF01080.17 GBG59044.1 - 0.34 9.6 0.6 0.37 9.5 0.6 1.1 1 0 0 1 1 1 0 Presenilin Sporozoite_P67 PF05642.11 GBG59044.1 - 0.61 8.1 7.8 0.84 7.6 7.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4637 PF15470.6 GBG59044.1 - 0.87 9.3 10.1 1.4 8.7 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PI3K_1B_p101 PF10486.9 GBG59044.1 - 0.88 7.3 6.2 0.98 7.1 6.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ferlin_C PF16165.5 GBG59044.1 - 1.6 8.6 3.1 2.9 7.8 3.1 1.3 1 0 0 1 1 1 0 Ferlin C-terminus SR-25 PF10500.9 GBG59044.1 - 2 7.9 13.4 3 7.4 13.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.23 GBG59045.1 - 1.3e-05 25.0 5.2 1.3e-05 25.0 5.2 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG59045.1 - 0.0048 16.8 2.3 0.016 15.2 2.3 1.8 1 0 0 1 1 1 1 Zinc knuckle ASCH PF04266.14 GBG59045.1 - 0.0087 16.6 0.7 0.023 15.2 0.1 2.0 2 0 0 2 2 2 1 ASCH domain zf-CCHC_2 PF13696.6 GBG59045.1 - 0.57 10.0 7.4 0.11 12.3 3.8 1.7 2 0 0 2 2 2 0 Zinc knuckle DUF3405 PF11885.8 GBG59045.1 - 2 6.9 8.5 2.9 6.4 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) ESM4 PF15952.5 GBG59045.1 - 4.5 7.7 9.9 0.88 10.0 0.3 2.3 1 1 1 2 2 2 0 Enhancer of split M4 family Pyridoxal_deC PF00282.19 GBG59047.1 - 7.3e-12 44.7 0.0 3.4e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain RT_RNaseH_2 PF17919.1 GBG59048.1 - 1.2e-24 86.3 0.0 3.1e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59048.1 - 3.6e-19 69.0 0.0 8.6e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59048.1 - 1.5e-17 63.5 0.5 5.8e-17 61.5 0.5 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59048.1 - 0.00059 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG59048.1 - 0.0085 16.3 0.3 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Baculo_PEP_C PF04513.12 GBG59048.1 - 0.26 11.3 0.6 41 4.2 0.1 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Retrotrans_gag PF03732.17 GBG59048.1 - 0.35 11.2 11.4 2.3 8.5 0.0 4.6 5 0 0 5 5 5 0 Retrotransposon gag protein DUF1465 PF07323.12 GBG59048.1 - 0.4 10.5 12.6 0.36 10.7 0.2 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1465) CLZ PF16526.5 GBG59048.1 - 0.47 10.8 7.9 6.2 7.2 0.5 4.1 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PIEZO PF15917.5 GBG59048.1 - 1.6 8.2 9.5 5.9 6.3 6.5 2.3 2 0 0 2 2 2 0 Piezo CAP160 PF07918.11 GBG59048.1 - 5 7.0 5.4 12 5.7 0.4 2.6 2 0 0 2 2 2 0 CAP160 repeat RT_RNaseH_2 PF17919.1 GBG59049.1 - 8.1e-21 73.9 0.0 2.2e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59049.1 - 4.8e-16 58.9 0.0 6.7e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59049.1 - 1.4e-10 41.4 0.0 3.4e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59050.1 - 0.0004 20.6 0.2 0.0011 19.2 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Syndecan PF01034.20 GBG59050.1 - 0.15 12.0 1.7 0.26 11.3 1.7 1.4 1 0 0 1 1 1 0 Syndecan domain CcmD PF04995.14 GBG59050.1 - 0.3 11.2 1.4 0.64 10.1 1.4 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Peptidase_M14 PF00246.24 GBG59051.1 - 7.1e-29 101.5 0.0 2.3e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 Zinc carboxypeptidase RNA_Me_trans PF04252.13 GBG59051.1 - 0.0002 21.0 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DUF2817 PF10994.8 GBG59051.1 - 0.037 13.4 0.0 0.087 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) APG9 PF04109.16 GBG59052.1 - 1.8e-175 584.6 5.9 2.4e-175 584.2 5.9 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 HoxA13_N PF12284.8 GBG59052.1 - 0.074 13.7 0.7 0.25 12.0 0.7 1.8 1 0 0 1 1 1 0 Hox protein A13 N terminal RSN1_7TM PF02714.15 GBG59052.1 - 0.091 12.1 3.4 0.046 13.0 0.7 1.8 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate MMS1_N PF10433.9 GBG59053.1 - 2.5e-06 26.4 0.0 5.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF2052 PF09747.9 GBG59053.1 - 8.3 6.5 26.6 1.7 8.7 6.5 2.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PHD PF00628.29 GBG59054.1 - 6.4e-11 42.0 4.2 6.4e-11 42.0 4.2 4.5 5 0 0 5 5 5 1 PHD-finger Nop14 PF04147.12 GBG59054.1 - 3e-05 22.5 32.3 4.6e-05 21.9 32.3 1.2 1 0 0 1 1 1 1 Nop14-like family zf-C2H2_4 PF13894.6 GBG59054.1 - 0.00019 22.0 38.2 0.12 13.3 1.3 6.7 7 0 0 7 7 6 3 C2H2-type zinc finger BUD22 PF09073.10 GBG59054.1 - 0.0013 18.2 25.1 0.0027 17.1 25.1 1.5 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 GBG59054.1 - 0.027 12.8 25.5 0.04 12.2 25.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 GBG59054.1 - 0.035 14.3 35.6 0.086 13.1 35.6 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Drc1-Sld2 PF11719.8 GBG59054.1 - 0.076 12.5 16.2 0.13 11.8 16.2 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Mpp10 PF04006.12 GBG59054.1 - 0.15 10.4 33.3 0.27 9.7 33.3 1.3 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 GBG59054.1 - 0.16 10.5 31.8 0.25 9.9 31.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zf_RING PF16744.5 GBG59054.1 - 0.2 11.8 18.7 0.36 11.0 1.1 4.9 6 0 0 6 6 5 0 KIAA1045 RING finger His_Me_b4a2 PF18275.1 GBG59054.1 - 0.22 11.6 2.8 15 5.7 0.0 4.5 4 0 0 4 4 4 0 His-Me finger endonuclease beta4-alpha2 domain SNURF PF07192.11 GBG59054.1 - 0.25 11.2 2.4 26 4.7 0.1 3.3 2 1 1 3 3 3 0 SNURF/RPN4 protein Pox_Ag35 PF03286.14 GBG59054.1 - 0.29 10.9 20.4 0.77 9.5 20.4 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.13 GBG59054.1 - 0.37 9.7 28.5 0.61 9.0 28.5 1.3 1 0 0 1 1 1 0 Paf1 DUF5523 PF17661.1 GBG59054.1 - 0.39 10.4 24.1 0.67 9.6 24.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) zf-C2H2 PF00096.26 GBG59054.1 - 0.62 10.6 26.9 3.5 8.3 0.3 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type SDA1 PF05285.12 GBG59054.1 - 1.1 8.7 41.6 0.35 10.3 36.4 2.1 2 0 0 2 2 2 0 SDA1 C1_1 PF00130.22 GBG59054.1 - 1.3 9.0 9.4 0.19 11.6 0.4 3.2 4 0 0 4 4 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nop53 PF07767.11 GBG59054.1 - 1.3 8.3 32.3 2.4 7.5 32.3 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 GBG59054.1 - 1.6 8.5 20.7 3.4 7.4 20.7 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 GBG59054.1 - 1.7 7.8 7.2 2.9 7.0 7.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Cwf_Cwc_15 PF04889.12 GBG59054.1 - 2.1 8.0 40.3 1.1 9.0 35.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-HC5HC2H PF13771.6 GBG59054.1 - 2.4 8.4 5.7 1.5 9.2 0.1 3.2 3 0 0 3 3 2 0 PHD-like zinc-binding domain SpoIIIAH PF12685.7 GBG59054.1 - 2.6 7.8 18.4 4.2 7.1 18.4 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SpoIIP PF07454.11 GBG59054.1 - 2.6 7.4 13.3 4.1 6.8 13.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) zf-C2H2_9 PF16293.5 GBG59054.1 - 3.3 7.6 6.1 11 6.0 0.1 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DDHD PF02862.17 GBG59054.1 - 3.7 7.7 4.8 8.2 6.5 4.8 1.6 1 0 0 1 1 1 0 DDHD domain Vps36-NZF-N PF16988.5 GBG59054.1 - 4.4 6.8 6.9 1.3 8.4 0.3 3.4 4 0 0 4 4 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF913 PF06025.12 GBG59054.1 - 4.9 6.0 10.1 7.7 5.4 10.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 GBG59054.1 - 5.5 6.1 21.0 9.2 5.4 21.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NPR3 PF03666.13 GBG59054.1 - 5.9 5.6 13.9 8.7 5.0 13.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Glyco_hydro_31 PF01055.26 GBG59055.1 - 2.9e-156 521.1 0.2 3.9e-156 520.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GBG59055.1 - 3.7e-27 94.8 0.0 3.6e-13 49.7 0.0 2.8 2 0 0 2 2 2 2 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 GBG59055.1 - 1.4e-06 28.5 0.1 3.3e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like Choline_kin_N PF04428.14 GBG59057.1 - 0.082 12.6 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Choline kinase N terminus CAP PF00188.26 GBG59058.1 - 1.5e-21 77.5 4.3 2.4e-21 76.9 4.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Xpo1 PF08389.12 GBG59060.1 - 2.9e-17 63.1 0.0 1.6e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 GBG59060.1 - 1.1e-05 25.2 0.1 3.4e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain UME PF08064.13 GBG59060.1 - 0.026 14.4 0.7 2.4 8.1 0.0 4.2 4 1 2 6 6 6 0 UME (NUC010) domain Xpo1 PF08389.12 GBG59061.1 - 4.3e-16 59.3 0.0 2.5e-15 56.8 0.0 2.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 GBG59061.1 - 1.2e-05 25.1 0.1 3.5e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain UME PF08064.13 GBG59061.1 - 0.15 12.0 1.3 2.4 8.1 0.0 3.8 5 1 1 6 6 6 0 UME (NUC010) domain Xpo1 PF08389.12 GBG59062.1 - 2.7e-17 63.2 0.0 1.6e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 GBG59062.1 - 1.2e-05 25.2 0.1 3.3e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain UME PF08064.13 GBG59062.1 - 0.027 14.4 0.4 2.3 8.2 0.0 4.0 4 1 1 5 5 5 0 UME (NUC010) domain RT_RNaseH_2 PF17919.1 GBG59063.1 - 3.9e-33 113.5 0.0 7.3e-33 112.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59063.1 - 4.9e-33 114.5 0.1 9.2e-33 113.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59063.1 - 4.5e-29 100.8 0.0 8.1e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59063.1 - 4.1e-06 27.3 0.0 1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59063.1 - 0.00063 19.5 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59063.1 - 0.0029 18.2 0.0 0.0067 17.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG59063.1 - 0.004 17.0 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Proteasome PF00227.26 GBG59064.1 - 2e-24 86.1 0.5 4.3e-24 85.0 0.5 1.5 1 1 0 1 1 1 1 Proteasome subunit GHMP_kinases_N PF00288.26 GBG59064.1 - 0.078 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain FmiP_Thoc5 PF09766.9 GBG59065.1 - 9.6e-56 189.6 0.0 1.7e-55 188.8 0.0 1.4 1 1 0 1 1 1 1 Fms-interacting protein/Thoc5 Sec2p PF06428.11 GBG59065.1 - 0.047 13.7 1.3 0.19 11.7 1.3 2.0 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p HNH_4 PF13395.6 GBG59067.1 - 3.7e-05 23.5 0.0 0.0001 22.1 0.0 1.7 2 0 0 2 2 2 1 HNH endonuclease HNH_5 PF14279.6 GBG59067.1 - 4.5e-05 23.2 0.3 0.00011 22.0 0.3 1.6 1 1 0 1 1 1 1 HNH endonuclease HNH PF01844.23 GBG59067.1 - 4.9e-05 23.4 0.1 0.00011 22.3 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease CHRD PF07452.12 GBG59069.1 - 9.8e-06 26.5 0.0 0.18 12.7 0.0 2.8 3 0 0 3 3 3 2 CHRD domain Lebercilin PF15619.6 GBG59070.1 - 1e-08 35.1 37.9 3.9e-08 33.2 37.9 2.0 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease His_Phos_2 PF00328.22 GBG59071.1 - 3.9e-118 395.1 0.3 3.9e-118 395.1 0.3 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 GBG59071.1 - 2.8e-18 65.9 0.1 2.8e-18 65.9 0.1 2.0 2 0 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 GBG59071.1 - 0.049 13.2 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 RimK-like ATP-grasp domain RT_RNaseH PF17917.1 GBG59072.1 - 1.2e-19 70.6 0.0 2.8e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59072.1 - 1.3e-18 66.9 0.0 3.3e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59072.1 - 1.2e-16 60.5 0.2 2.7e-16 59.4 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59072.1 - 6.2e-13 48.8 0.2 4.5e-08 32.9 0.1 2.7 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG59072.1 - 8.4e-08 32.4 0.0 3.2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG59072.1 - 0.00064 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Retrotrans_gag PF03732.17 GBG59072.1 - 0.00092 19.4 0.1 0.0036 17.5 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG59072.1 - 0.0021 17.8 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease PPIP5K2_N PF18086.1 GBG59073.1 - 1.3e-05 25.3 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain CCDC85 PF10226.9 GBG59073.1 - 0.0007 19.3 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 CCDC85 family DUF2385 PF09539.10 GBG59073.1 - 0.018 15.5 0.1 0.53 10.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) YscO PF07321.12 GBG59073.1 - 0.18 11.7 12.0 0.058 13.4 8.9 1.8 2 0 0 2 2 2 0 Type III secretion protein YscO bZIP_1 PF00170.21 GBG59073.1 - 7.8 6.7 8.2 0.62 10.2 1.4 2.4 2 0 0 2 2 2 0 bZIP transcription factor LMBR1 PF04791.16 GBG59074.1 - 2.7e-91 307.0 3.3 5.2e-91 306.1 3.3 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein CDC45 PF02724.14 GBG59076.1 - 0.15 10.4 16.7 0.21 9.8 16.7 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG59076.1 - 0.25 11.4 21.4 0.35 10.9 21.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GBG59076.1 - 0.3 10.5 21.0 0.39 10.1 21.0 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG59076.1 - 0.65 9.3 23.0 0.95 8.7 23.0 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GBG59076.1 - 0.84 8.3 2.9 0.96 8.2 2.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG59076.1 - 1.8 6.7 22.0 2.4 6.3 22.0 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG59076.1 - 2.8 7.4 11.0 4 6.9 11.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 GBG59076.1 - 4.5 5.9 8.8 5.8 5.6 8.8 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GBG59076.1 - 4.6 7.0 13.8 7.1 6.4 13.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YL1 PF05764.13 GBG59077.1 - 0.082 13.0 20.9 0.11 12.6 20.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG59077.1 - 0.15 11.4 22.2 0.22 10.8 22.2 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG59077.1 - 0.15 11.4 21.0 0.18 11.2 21.0 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG59077.1 - 0.94 8.2 3.9 1.1 8.0 3.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG59077.1 - 1.1 7.4 22.2 1.4 7.1 22.2 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG59077.1 - 1.3 8.6 11.0 1.6 8.2 11.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.12 GBG59077.1 - 1.4 8.7 13.2 2.2 8.0 13.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG59077.1 - 4.4 5.9 9.7 5.2 5.7 9.7 1.2 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG59078.1 - 1.6e-17 63.8 0.0 3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG59078.1 - 2.9e-09 36.8 1.1 5.3e-09 35.9 1.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 GBG59078.1 - 0.0002 22.0 8.3 0.0002 22.0 8.3 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 GBG59078.1 - 0.00077 19.3 0.1 0.013 15.3 0.0 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Peptidase_C14 PF00656.22 GBG59079.1 - 2.1e-26 93.4 0.0 4.4e-26 92.3 0.0 1.5 2 0 0 2 2 2 1 Caspase domain Aminotran_4 PF01063.19 GBG59081.1 - 8e-31 107.6 0.0 1.2e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV rve PF00665.26 GBG59081.1 - 8.9e-07 29.1 0.0 2.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain PPO1_KFDV PF12143.8 GBG59082.1 - 0.13 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) His_Phos_1 PF00300.22 GBG59082.1 - 0.19 11.4 0.1 0.24 11.1 0.1 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Chitin_bind_1 PF00187.19 GBG59083.1 - 6.5e-12 45.7 18.4 6.5e-12 45.7 18.4 2.5 2 0 0 2 2 2 1 Chitin recognition protein DUF659 PF04937.15 GBG59084.1 - 2.4e-25 89.2 0.0 4.6e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG59085.1 - 0.0042 17.3 0.1 0.0042 17.3 0.1 2.9 3 1 1 4 4 4 1 Retrotransposon gag protein TAF4 PF05236.14 GBG59085.1 - 0.0088 15.8 8.5 0.018 14.8 8.3 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Casc1_N PF15927.5 GBG59085.1 - 0.21 11.3 13.0 0.56 9.9 13.0 1.8 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF4666 PF15697.5 GBG59085.1 - 0.48 11.1 3.6 1.2 9.8 3.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) DUF5401 PF17380.2 GBG59085.1 - 2.5 6.1 12.5 3.4 5.6 12.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) eIF3_subunit PF08597.10 GBG59085.1 - 2.8 7.8 14.0 4.4 7.1 14.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ENT PF03735.14 GBG59086.1 - 7.6e-12 45.1 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 ENT domain CDC45 PF02724.14 GBG59086.1 - 1.7 6.8 8.3 2.4 6.4 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein ETRAMP PF09716.10 GBG59087.1 - 6.8e-05 22.8 19.0 0.0022 18.0 0.0 3.7 4 0 0 4 4 4 2 Malarial early transcribed membrane protein (ETRAMP) DUF4366 PF14283.6 GBG59087.1 - 0.00028 21.0 6.3 0.00028 21.0 6.3 4.3 3 1 2 5 5 5 1 Domain of unknown function (DUF4366) DUF1676 PF07898.13 GBG59087.1 - 0.00046 20.3 14.0 0.00046 20.3 14.0 7.9 4 2 3 7 7 7 1 Protein of unknown function (DUF1676) Orf78 PF06024.12 GBG59087.1 - 0.018 15.3 0.3 0.018 15.3 0.3 4.8 3 1 0 3 3 3 0 Orf78 (ac78) DUF3810 PF12725.7 GBG59087.1 - 0.025 13.9 0.3 0.047 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Otopetrin PF03189.13 GBG59087.1 - 0.091 11.6 0.0 0.091 11.6 0.0 3.0 2 1 0 2 2 2 0 Otopetrin GWT1 PF06423.12 GBG59087.1 - 1.5 8.9 0.0 1.5 8.9 0.0 2.6 2 1 0 2 2 2 0 GWT1 RVT_1 PF00078.27 GBG59088.1 - 1.3e-33 116.4 0.0 2.2e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gpUL132 PF11359.8 GBG59088.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 DUF16 PF01519.16 GBG59088.1 - 0.21 12.1 20.8 0.15 12.5 3.3 3.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF659 PF04937.15 GBG59089.1 - 2.6e-06 27.4 0.0 4.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59090.1 - 0.0016 18.2 0.1 0.0031 17.3 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2277 PF10041.9 GBG59090.1 - 0.13 12.6 1.5 0.73 10.2 1.5 2.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) Cwf_Cwc_15 PF04889.12 GBG59090.1 - 0.35 10.6 5.9 0.13 11.9 0.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RT_RNaseH_2 PF17919.1 GBG59091.1 - 1.8e-31 108.1 0.1 3e-31 107.4 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59091.1 - 8.5e-29 99.9 0.2 1.6e-28 99.1 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59091.1 - 1.1e-12 48.0 0.2 1.7e-12 47.4 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Codanin-1_C PF15296.6 GBG59092.1 - 4.8e-13 49.2 0.0 1.3e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Codanin-1 C-terminus Plavaka PF18759.1 GBG59093.1 - 9.6e-26 90.8 0.2 1.6e-25 90.0 0.2 1.3 1 0 0 1 1 1 1 Plavaka transposase Picorna_P3A PF06363.11 GBG59093.1 - 0.00083 19.2 0.0 1.8 8.5 0.0 3.3 3 0 0 3 3 3 2 Picornaviridae P3A protein ICAT PF06384.11 GBG59093.1 - 0.039 14.2 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Cpn60_TCP1 PF00118.24 GBG59094.1 - 1.5e-164 548.2 1.1 1.8e-164 548.0 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GEN1_C PF18380.1 GBG59095.1 - 0.056 14.3 3.4 0.53 11.2 1.5 2.7 2 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain RVT_1 PF00078.27 GBG59096.1 - 2.4e-27 95.9 0.3 4.4e-27 95.0 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59096.1 - 2.9e-13 49.7 0.1 7.3e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG59096.1 - 0.0078 16.4 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger PI-PLC-Y PF00387.19 GBG59097.1 - 5.6e-20 71.8 0.0 1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.19 GBG59097.1 - 3.1e-18 65.7 0.0 5.1e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Iso_dh PF00180.20 GBG59098.1 - 1.1e-138 462.1 0.0 1.3e-138 461.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fibrillarin PF01269.17 GBG59098.1 - 0.033 13.3 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin WD40 PF00400.32 GBG59099.1 - 3.2e-19 68.9 0.8 0.0009 20.0 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG59099.1 - 0.0016 18.7 0.0 4.9 7.5 0.0 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Pex14_N PF04695.13 GBG59099.1 - 0.95 10.1 37.9 1.9 9.2 23.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region APO_RNA-bind PF05634.11 GBG59100.1 - 0.00065 19.1 1.5 0.0014 18.1 1.5 1.6 1 1 0 1 1 1 1 APO RNA-binding DUF3255 PF11631.8 GBG59101.1 - 2.4 8.0 8.0 0.99 9.3 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3255) PUL PF08324.11 GBG59102.1 - 1.3e-48 165.7 0.5 1.6e-48 165.3 0.5 1.1 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 GBG59102.1 - 5.5e-40 134.6 20.2 2.8e-06 28.0 0.7 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat PFU PF09070.11 GBG59102.1 - 5.7e-37 126.4 0.0 9.9e-37 125.7 0.0 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.6 GBG59102.1 - 0.00035 20.6 0.0 0.29 11.2 0.0 2.8 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF3987 PF13148.6 GBG59103.1 - 8.4 5.3 11.7 16 4.4 11.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) zf-CCHC PF00098.23 GBG59104.1 - 0.00034 20.6 1.5 0.00074 19.5 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG59104.1 - 0.028 14.4 1.2 0.081 12.9 1.2 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG59104.1 - 0.045 13.6 2.1 0.062 13.1 0.8 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF3492 PF11997.8 GBG59104.1 - 0.35 10.6 2.1 0.66 9.7 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Peptidase_S49_N PF08496.10 GBG59104.1 - 1.3 9.1 12.5 0.26 11.4 8.6 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 GBG59104.1 - 2.7 7.7 13.2 5.9 6.6 13.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gam PF06064.11 GBG59104.1 - 6.5 7.1 10.6 0.12 12.6 1.3 2.8 2 1 1 3 3 3 0 Host-nuclease inhibitor protein Gam Pkinase PF00069.25 GBG59106.1 - 2.9e-55 187.5 0.0 4.6e-55 186.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG59106.1 - 6.2e-33 114.2 0.0 8.8e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GBG59106.1 - 4e-07 29.6 0.0 8.2e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_6 PF13405.6 GBG59106.1 - 1.1e-05 24.9 0.1 0.0012 18.6 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GBG59106.1 - 0.00039 19.7 0.1 0.0044 16.5 0.0 2.7 2 0 0 2 2 2 1 EF hand APH PF01636.23 GBG59106.1 - 0.0011 19.0 0.2 0.0046 16.9 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_7 PF13499.6 GBG59106.1 - 0.008 16.6 0.5 0.12 12.8 0.4 2.5 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG59106.1 - 0.012 15.1 1.4 0.027 14.0 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 GBG59106.1 - 0.024 14.9 0.1 1.5 9.2 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain Kinase-like PF14531.6 GBG59106.1 - 0.05 12.9 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.9 GBG59106.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 GBG59106.1 - 0.078 12.6 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family DUF659 PF04937.15 GBG59107.1 - 4.7e-29 101.2 0.3 7.4e-29 100.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59107.1 - 4.5e-05 23.2 1.2 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Syja_N PF02383.18 GBG59110.1 - 2.6e-88 296.4 0.0 3.3e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain RVT_1 PF00078.27 GBG59111.1 - 1.5e-28 99.8 0.2 5.8e-28 97.9 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59111.1 - 6e-23 80.8 0.0 1.9e-22 79.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59111.1 - 5e-22 78.2 0.0 1.6e-21 76.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59111.1 - 0.0042 17.3 0.0 0.021 15.1 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Allexi_40kDa PF05549.11 GBG59111.1 - 0.054 13.0 0.2 0.13 11.7 0.2 1.6 1 0 0 1 1 1 0 Allexivirus 40kDa protein TolA_bind_tri PF16331.5 GBG59111.1 - 0.26 11.4 7.5 0.75 9.9 7.5 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation RT_RNaseH_2 PF17919.1 GBG59112.1 - 8.6e-57 189.4 0.0 2.2e-28 98.2 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59112.1 - 2.1e-56 190.9 0.2 7e-30 104.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59112.1 - 8.5e-52 173.8 0.0 2.1e-27 95.4 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59112.1 - 4.2e-05 23.7 0.1 0.00035 20.8 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain RVP_2 PF08284.11 GBG59112.1 - 0.0037 17.0 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG59113.1 - 1.7e-28 99.7 0.0 2.7e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG59114.1 - 0.00069 20.1 0.0 0.0015 19.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59114.1 - 0.026 15.1 0.1 0.055 14.1 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG59114.1 - 0.035 13.9 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG59114.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG59114.1 - 0.15 11.8 1.2 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like DUF659 PF04937.15 GBG59119.1 - 1.6e-27 96.2 0.0 3.1e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DDE_Tnp_4 PF13359.6 GBG59121.1 - 2.5e-19 69.5 0.2 2.4e-18 66.3 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG59121.1 - 1.3e-10 41.2 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG59121.1 - 0.031 14.6 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG59122.1 - 4.6e-09 36.5 9.7 1e-08 35.4 4.2 3.1 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG59122.1 - 0.0066 16.7 2.9 0.015 15.6 1.7 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG59122.1 - 0.14 12.3 3.8 0.39 10.8 2.8 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MRI PF15325.6 GBG59126.1 - 0.2 12.7 3.9 4.6 8.4 0.3 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection RVT_1 PF00078.27 GBG59127.1 - 1.8e-28 99.6 0.1 2.9e-28 98.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59127.1 - 2.9e-24 85.0 0.0 6.1e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59127.1 - 1.5e-11 44.5 0.0 3.4e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59127.1 - 0.019 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_C48 PF02902.19 GBG59128.1 - 2e-05 24.5 0.3 3.3e-05 23.9 0.3 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain gag-asp_proteas PF13975.6 GBG59129.1 - 1.6e-06 28.6 0.1 4.9e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59129.1 - 0.00013 22.5 0.1 0.00045 20.8 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59129.1 - 0.0039 17.0 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59129.1 - 0.0082 15.9 0.2 0.019 14.7 0.1 1.7 2 0 0 2 2 2 1 Aspartyl protease Peptidase_A3 PF02160.15 GBG59129.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Topo_Zn_Ribbon PF08272.11 GBG59129.1 - 0.49 10.1 2.0 0.94 9.2 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Histone PF00125.24 GBG59130.1 - 5.3e-17 62.4 1.7 5.3e-17 62.4 1.7 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Retrotrans_gag PF03732.17 GBG59131.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG59131.1 - 0.13 12.4 1.7 0.24 11.5 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Glyco_transf_29 PF00777.18 GBG59133.1 - 4.3e-25 88.6 0.0 2.6e-20 72.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 29 (sialyltransferase) Apt1 PF10351.9 GBG59133.1 - 0.087 11.7 5.3 0.95 8.2 2.3 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF2052 PF09747.9 GBG59133.1 - 0.61 10.2 16.0 0.23 11.5 10.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RXT2_N PF08595.11 GBG59133.1 - 2.9 7.9 7.1 0.81 9.7 1.7 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Astro_capsid_p PF12226.8 GBG59133.1 - 4.6 6.3 8.2 8.3 5.5 8.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 GBG59133.1 - 8.7 4.5 16.9 0.2 9.9 9.5 1.8 2 0 0 2 2 2 0 CDC45-like protein RVT_1 PF00078.27 GBG59134.1 - 1.3e-27 96.8 0.0 2.4e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG59134.1 - 0.0028 18.3 5.0 0.0028 18.3 5.0 2.7 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase Ribophorin_II PF05817.14 GBG59135.1 - 4.5e-108 362.5 0.0 5e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II WD40 PF00400.32 GBG59136.1 - 0.00011 22.9 4.7 2.6 9.1 0.4 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG59136.1 - 0.00013 22.2 0.0 0.0081 16.4 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nuc_sug_transp PF04142.15 GBG59137.1 - 4.2e-46 157.6 7.8 6.3e-46 157.0 7.8 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GBG59137.1 - 3.7e-05 23.9 3.1 3.7e-05 23.9 3.1 2.5 2 1 0 2 2 2 1 EamA-like transporter family DUF975 PF06161.11 GBG59137.1 - 3.9 7.2 10.5 0.89 9.3 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF975) Presenilin PF01080.17 GBG59138.1 - 0.13 11.0 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 GBG59138.1 - 0.19 11.6 10.6 0.28 11.1 10.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Suf PF05843.14 GBG59138.1 - 1.1 9.1 4.3 1.6 8.6 4.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MIP-T3 PF10243.9 GBG59139.1 - 1.1e-38 131.7 0.0 1.9e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 GBG59139.1 - 2.4e-26 92.5 9.8 2.4e-26 92.5 9.8 2.7 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region TPX2 PF06886.11 GBG59139.1 - 0.13 12.5 5.8 0.44 10.8 5.8 1.9 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Podoplanin PF05808.11 GBG59139.1 - 1.2 9.3 4.2 4.2 7.4 4.2 1.9 1 0 0 1 1 1 0 Podoplanin DUF4200 PF13863.6 GBG59139.1 - 2 8.9 13.4 23 5.4 13.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) RVT_1 PF00078.27 GBG59140.1 - 2.1e-43 148.4 0.0 3.3e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG59141.1 - 1.5e-34 119.5 0.0 2.4e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59141.1 - 1.7e-19 69.7 0.0 3.6e-17 62.3 0.0 2.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59141.1 - 2.9e-08 34.0 0.0 9.1e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59141.1 - 8.8e-06 25.5 0.0 0.018 14.8 0.0 2.3 1 1 1 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59141.1 - 0.00097 19.7 0.1 0.0036 17.9 0.0 2.0 1 1 1 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59141.1 - 0.0042 17.6 0.0 0.014 16.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG59141.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG59141.1 - 0.11 12.3 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease SAPS PF04499.15 GBG59143.1 - 0.0056 15.5 0.4 0.0056 15.5 0.4 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein CobT PF06213.12 GBG59144.1 - 1.4 8.2 19.4 0.077 12.4 13.9 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT TatD_DNase PF01026.21 GBG59145.1 - 3.6e-63 213.3 0.0 6.2e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase Dynamin_M PF01031.20 GBG59145.1 - 7.2e-38 130.4 0.0 1.3e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 GBG59145.1 - 3.1e-35 121.7 0.1 5.4e-35 120.9 0.1 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GBG59145.1 - 7.6e-08 32.4 0.1 2.4e-07 30.8 0.1 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GBG59145.1 - 0.0087 16.1 0.2 0.71 10.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF3631 PF12307.8 GBG59145.1 - 0.013 15.7 0.7 1 9.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3631) FeoB_N PF02421.18 GBG59145.1 - 0.03 13.9 0.1 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 GBG59145.1 - 0.085 13.2 2.7 0.19 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 GBG59145.1 - 0.28 10.8 0.0 0.49 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RT_RNaseH_2 PF17919.1 GBG59146.1 - 1e-34 118.5 0.0 2.8e-34 117.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59146.1 - 1.2e-29 102.7 0.0 3.8e-29 101.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59146.1 - 2.2e-24 86.2 0.1 4.4e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59146.1 - 7.4e-16 58.0 0.3 1.6e-15 57.0 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain ABC_tran PF00005.27 GBG59146.1 - 2e-12 47.8 0.0 1.5e-11 45.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter rve PF00665.26 GBG59146.1 - 8.9e-12 45.3 0.0 1.3e-10 41.5 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain eIF3_subunit PF08597.10 GBG59146.1 - 2.1 8.2 5.8 3.7 7.4 5.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Flagellin_C PF00700.21 GBG59146.1 - 2.3 8.6 4.7 0.46 10.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region RVT_1 PF00078.27 GBG59147.1 - 4e-24 85.4 0.0 7.6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59147.1 - 5.8e-18 64.7 0.1 1.1e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG59147.1 - 4.2e-16 58.8 0.0 3.7e-14 52.6 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59147.1 - 5.1e-08 33.1 0.0 1.7e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG59147.1 - 9.1e-07 29.1 0.0 8e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59147.1 - 0.00014 22.4 0.0 0.00036 21.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59147.1 - 0.0003 21.3 0.0 0.00085 19.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Tudor-knot PF11717.8 GBG59147.1 - 0.00073 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF16 PF01519.16 GBG59147.1 - 0.015 15.8 2.1 0.02 15.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-H2C2 PF09337.10 GBG59147.1 - 0.029 14.6 0.0 0.073 13.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG59147.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG59147.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease AMP-binding_C_2 PF14535.6 GBG59147.1 - 0.14 12.5 0.0 0.53 10.6 0.0 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PTS_IIA PF02255.16 GBG59147.1 - 7.3 6.7 7.9 3.4 7.8 2.2 3.0 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit RT_RNaseH_2 PF17919.1 GBG59148.1 - 4.2e-32 110.2 0.0 6.3e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59148.1 - 4.2e-19 68.8 0.0 8.9e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2475 PF10629.9 GBG59148.1 - 2.5e-07 30.8 1.1 0.023 14.9 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2475) DUF2475 PF10629.9 GBG59149.1 - 0.26 11.5 1.6 0.49 10.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) DEAD PF00270.29 GBG59150.1 - 4.1e-40 137.4 0.0 7.3e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG59150.1 - 1.1e-30 106.2 0.1 4.7e-29 101.0 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG59150.1 - 5.7e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG59150.1 - 0.021 14.2 0.3 0.074 12.4 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 GBG59150.1 - 0.053 13.9 0.1 0.089 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 GBG59150.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.6 GBG59150.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain FUSC-like PF12805.7 GBG59150.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DEAD PF00270.29 GBG59151.1 - 3.9e-40 137.5 0.0 7e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG59151.1 - 1.1e-30 106.3 0.1 4.6e-29 101.0 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG59151.1 - 5.4e-05 23.3 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG59151.1 - 0.021 14.2 0.3 0.073 12.4 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 GBG59151.1 - 0.053 13.9 0.1 0.088 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 GBG59151.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.6 GBG59151.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain FUSC-like PF12805.7 GBG59151.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS RVT_1 PF00078.27 GBG59153.1 - 2.1e-28 99.4 0.1 2.9e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59153.1 - 7.9e-27 93.2 0.0 2e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59153.1 - 1.8e-22 79.6 0.0 3.7e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Yae1_N PF09811.9 GBG59154.1 - 4.7e-22 77.4 16.7 0.019 14.7 0.0 10.3 6 3 3 9 9 9 6 Essential protein Yae1, N terminal PC-Esterase PF13839.6 GBG59156.1 - 3.5e-57 194.3 0.0 2.6e-44 152.1 0.0 2.2 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 GBG59156.1 - 1.9e-09 37.7 4.0 1.9e-09 37.7 4.0 2.0 2 0 0 2 2 2 1 PMR5 N terminal Domain RCDG1 PF15725.5 GBG59156.1 - 0.039 14.4 2.5 0.092 13.2 2.5 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein PC-Esterase PF13839.6 GBG59157.1 - 1.1e-55 189.4 0.0 9.4e-44 150.2 0.0 2.2 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 GBG59157.1 - 6.3e-09 36.0 5.5 6.3e-09 36.0 5.5 2.0 2 0 0 2 2 2 1 PMR5 N terminal Domain SDA1 PF05285.12 GBG59158.1 - 0.076 12.4 15.0 0.13 11.7 15.0 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG59158.1 - 0.7 8.0 15.8 0.99 7.5 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 GBG59158.1 - 1.7 8.9 8.3 3.5 7.9 8.3 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PC-Esterase PF13839.6 GBG59159.1 - 1.3e-57 195.8 0.0 8.7e-46 156.9 0.1 2.2 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 GBG59159.1 - 1.3e-08 35.0 5.7 3.1e-08 33.8 5.7 1.7 1 0 0 1 1 1 1 PMR5 N terminal Domain Mito_carr PF00153.27 GBG59161.1 - 7.3e-54 179.7 10.0 3.9e-20 71.6 0.2 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein Gly-zipper_YMGG PF13441.6 GBG59161.1 - 3.9e-05 23.3 3.9 0.0012 18.5 0.0 3.9 4 1 0 4 4 4 2 YMGG-like Gly-zipper Myb_DNA-bind_4 PF13837.6 GBG59162.1 - 3.1e-06 27.5 0.6 3.1e-06 27.5 0.6 3.0 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Tubulin PF00091.25 GBG59162.1 - 0.011 16.0 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain MADF_DNA_bdg PF10545.9 GBG59162.1 - 0.022 15.0 0.2 0.075 13.4 0.2 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PEPCK_ATP PF01293.20 GBG59163.1 - 3.2e-212 705.3 0.0 3.8e-212 705.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 GBG59163.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 GBG59166.1 - 2.9e-37 128.0 0.1 4.2e-21 75.3 0.2 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GBG59166.1 - 1.1e-19 71.0 0.2 1.8e-11 44.1 0.7 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG59166.1 - 5.7e-07 29.6 0.2 5.6e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 GBG59166.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 GBG59166.1 - 0.0046 16.3 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 GBG59166.1 - 0.059 13.2 0.2 0.12 12.1 0.2 1.7 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.8 GBG59166.1 - 0.08 12.7 0.3 0.2 11.4 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RR_TM4-6 PF06459.12 GBG59167.1 - 0.49 10.2 15.5 0.53 10.1 15.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.10 GBG59167.1 - 0.77 9.1 26.3 0.92 8.8 26.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 GBG59167.1 - 4 5.5 22.8 4.6 5.3 22.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2828 PF11443.8 GBG59168.1 - 0.015 13.4 1.0 0.02 13.0 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Zip PF02535.22 GBG59168.1 - 7.4 5.7 9.6 10 5.2 9.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ras PF00071.22 GBG59170.1 - 9.1e-64 213.9 0.2 1.1e-63 213.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG59170.1 - 2.2e-33 115.0 0.1 5.1e-33 113.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG59170.1 - 3.8e-13 49.3 0.0 4.9e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GBG59170.1 - 1.7e-05 24.9 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GBG59170.1 - 0.00016 21.3 0.1 0.00074 19.1 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GBG59170.1 - 0.00016 21.6 0.1 0.18 11.7 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 GBG59170.1 - 0.0012 18.3 0.0 0.0025 17.2 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 GBG59170.1 - 0.016 15.5 0.1 0.18 12.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 GBG59170.1 - 0.09 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 GBG59170.1 - 0.091 12.5 0.4 0.53 10.0 0.0 1.9 1 1 0 2 2 2 0 AAA domain RT_RNaseH PF17917.1 GBG59171.1 - 1.6e-22 79.8 0.0 3.3e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59171.1 - 1.2e-21 76.6 0.0 2.4e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59171.1 - 2.3e-12 46.8 0.6 6.5e-12 45.4 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59171.1 - 1.4e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG59171.1 - 4.5e-07 30.3 0.3 1.5e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59171.1 - 7.3e-05 23.3 0.0 0.00023 21.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG59171.1 - 0.0095 15.7 0.2 0.019 14.7 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease Myb_DNA-binding PF00249.31 GBG59172.1 - 0.0066 16.6 0.0 0.55 10.5 0.0 3.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain CDK5_activator PF03261.15 GBG59172.1 - 4.4 6.8 13.1 12 5.3 13.1 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein RVT_1 PF00078.27 GBG59173.1 - 8.4e-22 77.8 0.1 1.9e-21 76.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59173.1 - 7.4e-16 58.0 0.0 1.7e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG59173.1 - 5.1e-12 45.7 0.0 5.5e-09 36.0 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59173.1 - 8.2e-11 42.1 0.1 2.5e-06 27.7 0.0 2.7 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59173.1 - 6.5e-09 36.0 0.0 2.2e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG59173.1 - 2e-05 24.4 0.0 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59173.1 - 0.00019 22.0 0.0 0.00045 20.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59173.1 - 0.00087 19.8 0.0 0.0024 18.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Trimer_CC PF08954.11 GBG59173.1 - 0.0045 16.5 0.6 0.022 14.3 0.6 2.3 1 0 0 1 1 1 1 Trimerisation motif Retrotrans_gag PF03732.17 GBG59173.1 - 0.016 15.4 0.0 0.17 12.2 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG59173.1 - 0.045 13.6 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Fib_alpha PF08702.10 GBG59173.1 - 4.3 7.5 5.0 1.3e+02 2.8 0.1 3.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family BBS2_Mid PF14783.6 GBG59174.1 - 0.11 12.5 0.2 0.57 10.2 0.1 1.8 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region RVT_1 PF00078.27 GBG59175.1 - 1.5e-38 132.5 0.2 6.4e-27 94.5 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59175.1 - 2.3e-28 98.1 0.0 6.4e-28 96.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59175.1 - 1.3e-26 92.9 0.0 3.3e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG59177.1 - 8.9e-35 119.8 0.0 1.3e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG59178.1 - 7.1e-14 51.7 0.1 1.9e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59178.1 - 2e-09 37.3 0.0 3.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG59178.1 - 4.2e-06 27.2 0.0 8.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59178.1 - 0.00018 22.1 0.0 0.00046 20.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG59178.1 - 0.021 14.6 0.6 0.037 13.8 0.6 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG59178.1 - 0.046 13.9 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger zf-met PF12874.7 GBG59179.1 - 7.2e-05 23.0 0.9 0.00015 22.1 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GBG59179.1 - 0.0006 20.0 0.3 0.00096 19.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.8 GBG59179.1 - 0.27 11.0 0.0 0.27 11.0 0.0 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF3449) PPR PF01535.20 GBG59180.1 - 9e-91 292.0 57.2 1.3e-05 25.1 0.0 24.1 24 1 0 24 24 24 17 PPR repeat PPR_2 PF13041.6 GBG59180.1 - 1e-85 281.7 22.8 2e-10 40.7 0.0 19.6 9 5 13 22 22 20 16 PPR repeat family PPR_1 PF12854.7 GBG59180.1 - 8.7e-67 220.5 2.7 1.4e-06 27.9 0.0 16.1 18 0 0 18 18 18 9 PPR repeat PPR_3 PF13812.6 GBG59180.1 - 2.1e-53 178.2 0.8 0.0004 20.4 0.1 14.0 8 4 5 16 16 15 10 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG59180.1 - 2.8e-35 121.6 0.0 2.6e-10 40.0 0.0 7.5 4 3 3 7 7 7 7 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG59180.1 - 1.1e-10 41.8 0.1 1.9 9.1 0.0 9.0 7 2 3 10 10 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG59180.1 - 2.8e-08 33.9 20.5 3.2 8.8 0.1 13.0 11 4 5 16 16 13 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG59180.1 - 7.5e-07 28.8 5.9 0.021 14.8 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 GBG59180.1 - 3.1e-06 27.0 2.4 1 9.8 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 GBG59180.1 - 9.8e-06 25.0 0.1 0.49 9.6 0.0 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG59180.1 - 0.00015 22.3 10.2 3.7 8.3 0.0 7.6 8 2 0 8 8 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG59180.1 - 0.00048 20.4 4.3 0.044 14.1 0.1 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat Clathrin PF00637.20 GBG59180.1 - 0.0006 19.7 0.0 9.2 6.1 0.0 4.9 5 0 0 5 5 5 0 Region in Clathrin and VPS ATP13 PF12921.7 GBG59180.1 - 0.00088 19.1 0.0 6.3 6.7 0.0 4.8 4 1 0 4 4 4 1 Mitochondrial ATPase expression TPR_1 PF00515.28 GBG59180.1 - 0.0016 18.2 3.4 0.13 12.1 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat Exog_C PF18026.1 GBG59180.1 - 0.0094 16.0 0.2 2.7 8.1 0.0 4.3 3 1 0 3 3 3 1 Endo/exonuclease (EXOG) C-terminal domain ECSIT PF06239.11 GBG59180.1 - 0.021 14.0 3.3 5.6 6.0 0.0 4.3 4 1 0 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_6 PF13174.6 GBG59180.1 - 0.026 15.1 5.0 62 4.5 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 GBG59180.1 - 0.072 13.2 5.2 0.16 12.1 5.2 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TPR_2 PF07719.17 GBG59180.1 - 0.081 13.1 12.5 2.5 8.4 0.0 7.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 GBG59180.1 - 0.1 13.3 17.5 0.81 10.5 0.7 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG59180.1 - 1.2 9.1 13.5 6.7 6.7 0.0 7.2 10 0 0 10 10 9 0 Tetratricopeptide repeat Mt_ATP-synt_B PF05405.14 GBG59180.1 - 1.4 8.5 5.9 3.4 7.3 5.9 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Retrotrans_gag PF03732.17 GBG59181.1 - 0.024 14.9 15.3 0.051 13.8 0.1 4.8 3 2 2 5 5 5 0 Retrotransposon gag protein LPP PF04728.13 GBG59181.1 - 0.42 11.0 13.0 4.2 7.8 0.1 4.7 4 0 0 4 4 4 0 Lipoprotein leucine-zipper CLZ PF16526.5 GBG59181.1 - 1.1 9.7 12.5 0.36 11.2 0.9 4.6 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snapin_Pallidin PF14712.6 GBG59181.1 - 9.5 6.7 10.2 1.5 9.3 0.0 3.9 4 0 0 4 4 4 0 Snapin/Pallidin RT_RNaseH_2 PF17919.1 GBG59182.1 - 2e-31 108.0 0.0 4.1e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59182.1 - 1.5e-30 106.4 0.0 2.7e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59182.1 - 8.1e-28 96.8 0.0 1.6e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59182.1 - 2.4e-16 59.6 0.0 5.1e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59182.1 - 9.5e-15 54.8 0.0 1.9e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain LRR_8 PF13855.6 GBG59182.1 - 2.7e-12 46.3 5.0 7.1e-08 32.1 0.2 2.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 GBG59182.1 - 0.0002 21.7 6.9 0.0047 17.3 0.2 3.7 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) zf-H2C2 PF09337.10 GBG59182.1 - 0.0035 17.5 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG59182.1 - 0.051 13.3 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RT_RNaseH PF17917.1 GBG59183.1 - 1.1e-22 80.3 0.0 3.4e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59183.1 - 2.5e-21 75.6 0.0 5.1e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59183.1 - 5.7e-14 52.0 0.3 1.7e-13 50.4 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59183.1 - 7.7e-12 45.5 0.0 1.8e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG59183.1 - 4.6e-07 29.6 0.0 8.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG59183.1 - 1.2e-06 28.9 0.0 3.5e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59183.1 - 5.6e-05 23.7 0.0 0.00014 22.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease SQHop_cyclase_N PF13249.6 GBG59183.1 - 0.00021 20.5 0.0 0.0005 19.2 0.0 1.6 1 0 0 1 1 1 1 Squalene-hopene cyclase N-terminal domain RVP PF00077.20 GBG59183.1 - 0.0024 18.1 0.0 0.0061 16.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59183.1 - 0.15 11.8 0.6 0.3 10.9 0.6 1.4 1 0 0 1 1 1 0 Aspartyl protease LRR_4 PF12799.7 GBG59184.1 - 5.2e-05 23.5 1.8 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG59184.1 - 0.00027 20.6 4.2 0.2 11.5 1.3 2.3 2 0 0 2 2 2 2 Leucine rich repeat RRN3 PF05327.11 GBG59184.1 - 0.065 11.8 6.8 0.073 11.6 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TraG_N PF07916.11 GBG59184.1 - 0.14 10.9 21.6 0.19 10.5 21.6 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Anoctamin PF04547.12 GBG59184.1 - 0.22 10.3 4.7 0.27 10.0 4.7 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel LRR_1 PF00560.33 GBG59184.1 - 0.27 11.9 2.8 12 6.9 1.7 3.0 2 1 1 3 3 3 0 Leucine Rich Repeat Pex24p PF06398.11 GBG59184.1 - 0.44 9.5 4.8 0.57 9.1 4.8 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DNA_pol_phi PF04931.13 GBG59184.1 - 0.87 7.6 13.8 1.2 7.2 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG59184.1 - 2.4 6.3 6.0 3.1 6.0 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Osteopontin PF00865.18 GBG59184.1 - 7.7 5.9 20.4 9.9 5.6 20.4 1.1 1 0 0 1 1 1 0 Osteopontin RRN3 PF05327.11 GBG59185.1 - 0.03 12.9 6.2 0.031 12.9 6.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Anoctamin PF04547.12 GBG59185.1 - 0.096 11.5 4.0 0.12 11.2 4.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel TraG_N PF07916.11 GBG59185.1 - 0.11 11.4 21.6 0.14 11.0 21.6 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region SUR7 PF06687.12 GBG59185.1 - 0.14 11.8 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 SUR7/PalI family Pex24p PF06398.11 GBG59185.1 - 0.25 10.3 4.5 0.31 10.0 4.5 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DNA_pol_phi PF04931.13 GBG59185.1 - 0.52 8.4 13.5 0.67 8.0 13.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Osteopontin PF00865.18 GBG59185.1 - 5.9 6.3 20.4 7.5 6.0 20.4 1.1 1 0 0 1 1 1 0 Osteopontin RVT_1 PF00078.27 GBG59186.1 - 7.3e-30 104.1 0.1 3.3e-29 102.0 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59186.1 - 3.5e-10 40.1 1.3 8.3e-10 38.9 0.4 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59186.1 - 2.3e-08 33.9 0.0 5.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59186.1 - 2.7e-08 34.3 0.0 8.6e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59186.1 - 2.3e-05 24.9 0.0 9.9e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG59186.1 - 0.00015 21.7 0.0 0.021 14.9 0.1 3.0 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG59186.1 - 0.0061 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease TolA_bind_tri PF16331.5 GBG59186.1 - 0.067 13.3 6.4 0.19 11.8 6.4 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation rve PF00665.26 GBG59187.1 - 9e-17 61.4 0.0 2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG59187.1 - 0.02 15.0 0.6 0.039 14.1 0.6 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain Rap_GAP PF02145.15 GBG59187.1 - 0.04 13.4 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Rap/ran-GAP Chromo PF00385.24 GBG59187.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG59187.1 - 0.17 11.6 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) CNOT1_HEAT_N PF16419.5 GBG59187.1 - 0.18 11.4 0.1 0.28 10.8 0.1 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat zf-CCHC_3 PF13917.6 GBG59188.1 - 0.0019 18.1 1.0 0.0052 16.7 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG59188.1 - 0.6 10.3 4.9 1.1 9.4 4.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG59189.1 - 4.6e-33 114.1 0.0 7.8e-31 106.9 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG59189.1 - 5.3e-14 52.3 0.0 1.2e-13 51.1 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG59189.1 - 0.014 15.0 1.5 4.9 6.7 0.2 2.8 3 0 0 3 3 3 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG59190.1 - 6.2e-06 26.5 0.2 1.8e-05 25.0 0.2 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF3119 PF11317.8 GBG59191.1 - 0.0087 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) Nop52 PF05997.12 GBG59192.1 - 3.7e-57 193.6 0.7 3.7e-57 193.6 0.7 1.5 2 0 0 2 2 1 1 Nucleolar protein,Nop52 SDA1 PF05285.12 GBG59192.1 - 3.3e-06 26.8 34.7 5.3e-06 26.1 34.7 1.3 1 0 0 1 1 1 1 SDA1 TAN PF11640.8 GBG59192.1 - 0.00036 20.7 0.0 0.00091 19.4 0.0 1.6 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Mpp10 PF04006.12 GBG59192.1 - 0.0016 17.0 29.0 0.0022 16.5 29.0 1.2 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 GBG59192.1 - 0.0018 16.6 39.5 0.0025 16.1 39.5 1.1 1 0 0 1 1 1 1 Nop14-like family Hid1 PF12722.7 GBG59192.1 - 0.0034 15.6 0.1 0.0044 15.2 0.1 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Na_trans_assoc PF06512.13 GBG59192.1 - 0.0047 17.2 14.8 0.0047 17.2 14.8 1.6 2 0 0 2 2 2 1 Sodium ion transport-associated SAPS PF04499.15 GBG59192.1 - 0.006 15.4 10.6 0.0085 14.9 10.6 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein CNDH2_C PF16858.5 GBG59192.1 - 0.31 10.9 15.8 0.54 10.1 15.8 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF913 PF06025.12 GBG59192.1 - 1.4 7.8 8.4 2.7 6.9 8.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SURF2 PF05477.11 GBG59192.1 - 2.9 7.5 19.9 4.7 6.8 19.9 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Zip PF02535.22 GBG59192.1 - 7.6 5.7 8.9 11 5.1 8.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1442 PF07279.11 GBG59193.1 - 0.09 12.1 0.0 0.49 9.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1442) RT_RNaseH PF17917.1 GBG59194.1 - 2.4e-23 82.4 0.0 6e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59194.1 - 2.6e-22 78.7 0.0 5.3e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59194.1 - 1.7e-18 66.5 0.7 3.3e-18 65.5 0.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59194.1 - 6.6e-09 35.6 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG59194.1 - 0.008 16.4 0.2 0.015 15.5 0.2 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DEPP PF15343.6 GBG59195.1 - 0.052 13.6 0.9 0.052 13.6 0.9 2.5 1 1 2 3 3 3 0 Decidual protein induced by progesterone family DUF507 PF04368.13 GBG59196.1 - 0.027 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF507) gag-asp_proteas PF13975.6 GBG59197.1 - 4.1e-07 30.5 0.1 1.4e-06 28.8 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59197.1 - 2e-05 25.2 0.5 5.6e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG59197.1 - 0.00049 19.9 0.1 0.00085 19.1 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG59197.1 - 0.03 14.0 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Myb_DNA-bind_4 PF13837.6 GBG59198.1 - 1.2e-09 38.4 3.4 2.6e-09 37.3 3.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG59198.1 - 0.64 10.4 6.3 0.083 13.2 1.7 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF229 PF02995.17 GBG59199.1 - 7.1e-39 133.8 0.1 3.8e-38 131.4 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF229) RT_RNaseH PF17917.1 GBG59199.1 - 1.9e-19 69.9 0.1 5.5e-19 68.4 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59199.1 - 4.3e-16 58.8 0.5 1.2e-15 57.3 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG59199.1 - 4.8e-13 49.0 0.0 1.3e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sulfatase PF00884.23 GBG59199.1 - 3.8e-06 26.5 0.3 1.8e-05 24.3 0.3 1.9 1 1 0 1 1 1 1 Sulfatase Retrotrans_gag PF03732.17 GBG59199.1 - 0.00021 21.5 0.4 1.5 9.1 0.0 3.7 3 0 0 3 3 3 2 Retrotransposon gag protein Phosphodiest PF01663.22 GBG59199.1 - 0.0012 18.5 0.2 0.0056 16.3 0.0 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase BAR PF03114.18 GBG59199.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 BAR domain DUF2070 PF09843.9 GBG59199.1 - 5.1 5.3 9.2 7.8 4.7 9.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RVT_1 PF00078.27 GBG59200.1 - 1.3e-37 129.5 0.0 2.2e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pectinesterase PF01095.19 GBG59201.1 - 1.3e-06 27.4 0.1 1.9e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Pectinesterase PPR_2 PF13041.6 GBG59202.1 - 5.3e-67 221.8 4.7 2.5e-12 46.8 0.6 10.9 7 2 4 11 11 11 10 PPR repeat family PPR_1 PF12854.7 GBG59202.1 - 2.1e-63 209.7 5.4 8.8e-07 28.5 0.0 10.4 10 0 0 10 10 10 9 PPR repeat PPR PF01535.20 GBG59202.1 - 4.6e-60 195.8 23.1 2.8e-07 30.3 0.1 13.2 14 0 0 14 14 14 11 PPR repeat PPR_3 PF13812.6 GBG59202.1 - 1.4e-40 137.2 0.0 2.2e-06 27.6 0.0 10.0 7 2 4 11 11 11 9 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG59202.1 - 2.6e-19 69.4 9.2 5.1e-05 22.7 0.3 6.4 5 2 1 6 6 6 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG59202.1 - 4.3e-06 27.1 4.8 3.2 8.3 0.0 7.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG59202.1 - 9.3e-05 22.9 6.1 52 5.0 0.1 8.3 8 1 0 9 9 9 0 Tetratricopeptide repeat BUD22 PF09073.10 GBG59203.1 - 0.3 10.4 18.3 0.36 10.1 18.3 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG59203.1 - 1.5 7.1 12.4 1.8 6.8 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG59203.1 - 2 6.5 17.1 2 6.5 17.1 1.0 1 0 0 1 1 1 0 Nop14-like family eIF3_N PF09440.10 GBG59203.1 - 6.9 7.1 5.7 2.1 8.8 2.5 1.7 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain SDA1 PF05285.12 GBG59203.1 - 7 6.0 18.8 7.8 5.8 18.8 1.1 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG59204.1 - 8.2e-32 110.5 0.1 5.1e-26 91.6 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59204.1 - 1.1e-16 60.6 0.0 2.8e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59204.1 - 2.1e-11 44.1 0.0 6e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG59204.1 - 0.00018 21.7 0.0 0.00041 20.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PilN PF05137.13 GBG59204.1 - 0.18 12.0 0.0 2.8 8.1 0.0 2.3 1 1 1 2 2 2 0 Fimbrial assembly protein (PilN) Pyr_redox_2 PF07992.14 GBG59205.1 - 3.8e-72 243.0 6.3 5.8e-72 242.4 6.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GBG59205.1 - 1.4e-40 138.0 0.6 3.1e-40 136.9 0.6 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GBG59205.1 - 1.9e-25 89.2 4.5 2.5e-20 72.8 0.3 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG59205.1 - 1.8e-13 50.4 2.7 1.5e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GBG59205.1 - 2.6e-10 40.3 3.8 2.6e-10 40.3 3.8 2.6 2 2 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GBG59205.1 - 7.7e-10 38.4 4.1 1.5e-08 34.1 2.8 2.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GBG59205.1 - 3.6e-07 29.6 2.4 3.6e-07 29.6 2.4 3.9 3 1 2 5 5 5 1 FAD binding domain NAD_binding_8 PF13450.6 GBG59205.1 - 4.5e-07 30.0 2.8 5.1e-06 26.6 0.5 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 GBG59205.1 - 4.6e-05 23.1 3.7 0.0026 17.3 0.0 3.2 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 GBG59205.1 - 4.9e-05 22.7 7.9 0.039 13.3 0.2 3.2 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 GBG59205.1 - 6.2e-05 22.4 11.9 0.0011 18.3 1.3 3.2 2 1 1 3 3 3 2 FAD binding domain Thi4 PF01946.17 GBG59205.1 - 7.1e-05 22.1 2.0 0.00011 21.5 0.1 2.2 3 0 0 3 3 3 1 Thi4 family K_oxygenase PF13434.6 GBG59205.1 - 8.7e-05 21.8 1.1 0.08 12.1 0.1 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 GBG59205.1 - 0.00019 20.3 11.6 0.00025 19.9 1.0 3.4 3 1 1 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.12 GBG59205.1 - 0.0022 17.1 4.7 0.098 11.7 0.1 3.2 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 GBG59205.1 - 0.0045 17.4 2.7 2 8.9 0.1 3.3 3 0 0 3 3 3 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 GBG59205.1 - 0.018 15.0 0.1 0.018 15.0 0.1 3.5 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 GBG59205.1 - 0.042 13.4 17.2 0.26 10.8 3.1 4.1 3 1 0 4 4 4 0 FAD dependent oxidoreductase XdhC_C PF13478.6 GBG59205.1 - 0.044 14.3 0.2 10 6.7 0.0 2.8 3 0 0 3 3 3 0 XdhC Rossmann domain Amino_oxidase PF01593.24 GBG59205.1 - 0.14 11.5 3.5 0.15 11.3 0.1 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 GBG59205.1 - 0.32 9.8 2.6 0.28 10.0 0.8 1.8 2 0 0 2 2 2 0 Tryptophan halogenase RVT_1 PF00078.27 GBG59206.1 - 2e-12 47.1 0.0 3.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mur_ligase_M PF08245.12 GBG59208.1 - 3.4e-54 183.8 0.0 5.7e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 GBG59208.1 - 4.2e-19 68.6 0.0 5.7e-18 65.0 0.0 2.7 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 GBG59208.1 - 9.2e-12 45.1 0.2 5e-11 42.8 0.1 2.3 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Myc_N PF01056.18 GBG59208.1 - 0.05 13.5 2.0 0.081 12.8 2.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4820 PF16091.5 GBG59208.1 - 0.076 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NOA36 PF06524.12 GBG59208.1 - 0.16 11.2 3.6 0.28 10.5 3.6 1.3 1 0 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.10 GBG59208.1 - 2 9.1 10.7 4.8 7.9 10.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pox_Ag35 PF03286.14 GBG59208.1 - 4.7 7.0 6.1 8.1 6.2 6.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_60s PF00428.19 GBG59208.1 - 7.3 7.3 22.9 0.61 10.7 16.5 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein Cellulase PF00150.18 GBG59209.1 - 1.1e-10 41.5 0.7 1.5e-10 41.0 0.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) gag-asp_proteas PF13975.6 GBG59210.1 - 8e-08 32.7 0.0 2.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59210.1 - 6.1e-07 30.0 0.0 1.8e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease DUF1664 PF07889.12 GBG59210.1 - 0.045 13.8 3.4 0.16 12.0 3.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HSD3 PF15244.6 GBG59210.1 - 0.49 9.8 7.7 0.076 12.5 0.5 2.5 2 0 0 2 2 2 0 Spermatogenesis-associated protein 7, or HSD3 Anti-adapt_IraP PF10796.9 GBG59210.1 - 0.77 10.4 3.8 31 5.2 0.1 2.7 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein NosD PF05048.13 GBG59211.1 - 0.81 8.9 8.0 1.2 8.3 8.0 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 GBG59212.1 - 5.8e-06 26.1 0.4 1.3e-05 24.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG59212.1 - 6.2e-06 26.0 0.3 1.5e-05 24.7 0.3 1.7 1 0 0 1 1 1 1 F-box domain CENP-B_dimeris PF09026.10 GBG59212.1 - 0.0062 16.9 17.6 0.0062 16.9 17.6 2.2 2 0 0 2 2 2 1 Centromere protein B dimerisation domain LRR_6 PF13516.6 GBG59212.1 - 0.0068 16.4 0.5 30 5.0 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 GBG59212.1 - 0.022 15.2 0.0 1.6 9.3 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LEA_3 PF03242.13 GBG59212.1 - 0.27 12.0 4.2 0.47 11.2 2.3 2.2 3 0 0 3 3 3 0 Late embryogenesis abundant protein RXT2_N PF08595.11 GBG59212.1 - 0.72 9.9 6.0 1.6 8.7 6.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 GBG59212.1 - 0.73 9.7 5.6 1.2 8.9 5.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.8 GBG59212.1 - 0.74 10.0 12.6 1.4 9.1 12.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.11 GBG59212.1 - 1 7.8 2.7 3.9 5.9 3.7 1.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GBG59212.1 - 1.1 7.3 10.1 1.8 6.6 10.1 1.3 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 GBG59212.1 - 1.4 8.6 4.4 0.65 9.6 1.7 1.8 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 GBG59212.1 - 7.4 4.5 15.9 9.9 4.1 15.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG59212.1 - 8.3 4.6 8.7 14 3.8 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 GBG59212.1 - 8.7 6.2 10.1 4.8 7.1 6.7 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 GBG59214.1 - 1.3e-19 70.8 1.0 1.3e-19 70.8 1.0 3.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG59214.1 - 1.5e-05 25.2 0.2 4.4e-05 23.7 0.2 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GBG59214.1 - 0.006 17.1 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TAF PF02969.17 GBG59214.1 - 0.014 15.6 0.3 0.014 15.6 0.3 1.9 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 GBG59214.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 CENP-S protein V_ATPase_I PF01496.19 GBG59214.1 - 3.2 5.6 4.1 5.1 4.9 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Trypsin PF00089.26 GBG59215.1 - 7.4e-09 35.7 0.4 0.0023 17.8 0.2 2.4 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 GBG59215.1 - 8.5e-09 36.5 0.1 7.5e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 Trypsin-like peptidase domain EGF_2 PF07974.13 GBG59215.1 - 0.00022 21.5 27.3 0.0014 19.0 10.3 4.6 3 1 1 4 4 4 2 EGF-like domain YchF-GTPase_C PF06071.13 GBG59216.1 - 4.2e-39 132.6 0.5 1.2e-38 131.2 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GBG59216.1 - 3.1e-21 75.6 0.0 1.9e-20 73.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG59216.1 - 4.9e-08 32.7 0.0 1.3e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 GBG59216.1 - 0.0062 17.1 0.1 0.07 13.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter MeaB PF03308.16 GBG59216.1 - 0.023 13.7 0.2 0.22 10.4 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB 6PF2K PF01591.18 GBG59216.1 - 0.023 14.0 0.3 4.6 6.5 0.1 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Roc PF08477.13 GBG59216.1 - 0.04 14.1 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 GBG59216.1 - 0.057 14.0 0.1 0.57 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain TGS PF02824.21 GBG59216.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 TGS domain L_lactis_ph-MCP PF06673.11 GBG59216.1 - 0.55 9.2 3.5 0.78 8.7 2.6 1.6 2 0 0 2 2 2 0 Lactococcus lactis bacteriophage major capsid protein Myb_DNA-bind_5 PF13873.6 GBG59217.1 - 0.0041 17.2 0.4 0.0062 16.6 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Spt5_N PF11942.8 GBG59218.1 - 0.19 12.7 5.5 8.1 7.5 0.5 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF587 PF04532.12 GBG59219.1 - 0.0028 17.0 0.1 0.37 10.0 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF587) F-box-like PF12937.7 GBG59223.1 - 0.0031 17.4 1.6 0.018 14.9 0.1 2.6 3 0 0 3 3 3 1 F-box-like Retrotrans_gag PF03732.17 GBG59224.1 - 0.0024 18.1 0.2 0.0096 16.2 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG59224.1 - 0.15 12.1 1.2 0.33 11.0 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4192 PF13830.6 GBG59224.1 - 0.51 10.4 5.1 0.64 10.0 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4192) Hydrolase_4 PF12146.8 GBG59225.1 - 9.6e-62 208.4 0.0 1.4e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG59225.1 - 4e-11 43.1 0.0 1.3e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GBG59225.1 - 3.7e-09 36.4 0.0 2.5e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GBG59225.1 - 4.7e-07 30.6 0.0 7.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GBG59225.1 - 2.5e-05 24.2 0.0 0.00044 20.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 GBG59225.1 - 0.00017 21.3 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 GBG59225.1 - 0.0022 17.6 0.0 0.024 14.2 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 GBG59225.1 - 0.0053 16.3 0.0 0.67 9.5 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 GBG59225.1 - 0.0075 15.0 0.0 0.84 8.2 0.0 2.8 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 GBG59225.1 - 0.011 15.6 0.0 2.5 7.8 0.0 3.0 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 GBG59225.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein EF-hand_7 PF13499.6 GBG59226.1 - 6.5e-26 90.6 0.5 9.7e-14 51.6 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG59226.1 - 1.4e-18 65.0 2.8 2.8e-05 23.3 0.0 4.6 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GBG59226.1 - 5.5e-18 63.3 2.4 1.3e-05 24.8 0.0 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 GBG59226.1 - 3.4e-17 62.0 3.3 3.3e-07 30.0 0.0 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GBG59226.1 - 1.4e-14 52.8 0.9 0.00022 20.6 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 GBG59226.1 - 0.00068 19.9 0.1 0.76 10.1 0.0 3.0 2 2 1 3 3 3 2 EF-hand domain EF-hand_11 PF08976.11 GBG59226.1 - 0.0092 16.8 0.0 0.094 13.6 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 GBG59226.1 - 0.015 15.5 0.0 0.53 10.5 0.0 2.6 2 1 0 2 2 2 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 GBG59226.1 - 0.06 13.7 0.1 0.19 12.1 0.0 1.9 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CHAT PF12770.7 GBG59226.1 - 0.074 12.4 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 CHAT domain FDX-ACB PF03147.14 GBG59226.1 - 0.097 13.1 0.0 0.2 12.1 0.0 1.6 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain Chloroa_b-bind PF00504.21 GBG59227.1 - 0.00053 20.5 0.1 0.0017 18.9 0.0 1.7 1 1 1 2 2 2 1 Chlorophyll A-B binding protein zf-UBP PF02148.19 GBG59228.1 - 2.3e-15 56.7 13.8 3.7e-15 56.0 13.8 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein ADK_lid PF05191.14 GBG59228.1 - 4.7 7.3 6.9 26 4.9 1.7 2.9 2 1 0 2 2 2 0 Adenylate kinase, active site lid POT1 PF02765.17 GBG59229.1 - 3.5e-24 85.3 0.0 6.3e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 GBG59229.1 - 1.1e-07 31.9 0.0 6.6e-06 26.1 0.0 2.8 2 1 0 2 2 2 1 ssDNA-binding domain of telomere protection protein KTI12 PF08433.10 GBG59230.1 - 3.4e-74 249.7 0.0 3.9e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 GBG59230.1 - 6.5e-09 36.1 0.0 1.8e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GBG59230.1 - 0.00022 21.8 0.0 0.00039 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GBG59230.1 - 0.023 14.0 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 GBG59230.1 - 0.067 13.5 0.0 0.17 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 GBG59230.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 GBG59230.1 - 0.1 13.1 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GBG59230.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 GBG59231.1 - 7.6e-36 123.8 0.0 9.3e-35 120.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG59231.1 - 8.8e-36 123.5 0.0 1.5e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SGL PF08450.12 GBG59231.1 - 5.1e-09 36.1 0.1 0.021 14.4 0.0 3.5 2 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GBG59231.1 - 1.9e-07 30.7 0.8 0.22 11.6 0.0 5.3 5 0 0 5 5 5 2 NHL repeat Arylesterase PF01731.20 GBG59231.1 - 5.8e-06 26.4 0.0 0.042 14.0 0.1 3.6 3 1 1 4 4 4 2 Arylesterase Str_synth PF03088.16 GBG59231.1 - 0.0046 17.0 0.0 58 3.9 0.0 4.8 4 1 1 5 5 5 0 Strictosidine synthase PQQ PF01011.21 GBG59231.1 - 0.15 12.0 0.0 0.53 10.3 0.0 2.0 1 0 0 1 1 1 0 PQQ enzyme repeat Peptidase_M16_C PF05193.21 GBG59232.1 - 3.8e-52 177.0 0.0 1.7e-26 93.3 0.0 3.4 2 2 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GBG59232.1 - 6.6e-18 65.1 0.0 1.8e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) MAP70 PF07058.11 GBG59232.1 - 4.7 5.8 6.2 10 4.8 6.2 1.4 1 0 0 1 1 1 0 Microtubule-associated protein 70 C_Hendra PF16821.5 GBG59234.1 - 0.29 11.0 4.6 0.48 10.3 4.6 1.3 1 0 0 1 1 1 0 C protein from hendra and measles viruses AAA_17 PF13207.6 GBG59234.1 - 2.5 8.5 5.3 18 5.7 0.5 2.8 1 1 3 4 4 4 0 AAA domain RVT_1 PF00078.27 GBG59235.1 - 4.2e-26 91.8 0.1 7.3e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59235.1 - 9.6e-16 57.7 0.0 2.5e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59235.1 - 5.4e-06 26.6 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ORF6C PF10552.9 GBG59235.1 - 0.054 13.6 0.1 0.35 11.0 0.0 2.4 3 0 0 3 3 3 0 ORF6C domain SRP-alpha_N PF04086.13 GBG59235.1 - 0.073 13.0 9.4 0.13 12.1 9.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Kelch_3 PF13415.6 GBG59235.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain RVT_1 PF00078.27 GBG59236.1 - 1.3e-26 93.5 0.1 2.3e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59236.1 - 3.7e-10 40.0 0.1 8.9e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59236.1 - 2.6e-05 24.2 0.0 6.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59237.1 - 1.1e-24 86.7 0.0 2.4e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59237.1 - 6.3e-23 80.7 0.0 1.4e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59237.1 - 1e-10 41.5 0.0 3.3e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-TRAF PF02176.18 GBG59239.1 - 1.6e-08 35.1 20.0 3.6e-06 27.6 0.1 3.7 2 1 1 3 3 3 2 TRAF-type zinc finger Sina PF03145.16 GBG59239.1 - 1e-07 32.2 6.6 0.00022 21.3 1.7 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-C3HC4_2 PF13923.6 GBG59239.1 - 2.1e-05 24.2 7.8 2.1e-05 24.2 7.8 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG59239.1 - 2.4e-05 24.2 7.2 2.4e-05 24.2 7.2 3.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG59239.1 - 8.4e-05 22.4 5.9 8.4e-05 22.4 5.9 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG59239.1 - 0.0002 21.3 4.9 0.0002 21.3 4.9 2.9 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GBG59239.1 - 0.0007 19.4 10.0 0.0007 19.4 10.0 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GBG59239.1 - 0.0042 17.4 7.9 0.0042 17.4 7.9 3.5 2 1 1 3 3 3 1 Ring finger domain zf-TRAF_2 PF15965.5 GBG59239.1 - 1.3 9.5 20.6 0.3 11.6 1.7 3.3 2 1 1 3 3 3 0 TRAF-like zinc-finger VIR_N PF15912.5 GBG59239.1 - 10 5.7 7.1 16 5.0 7.1 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Myb_DNA-bind_4 PF13837.6 GBG59240.1 - 3.7e-09 36.8 1.6 7.4e-09 35.9 1.6 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG59242.1 - 1e-26 92.8 0.0 1.8e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59242.1 - 3.6e-21 75.4 0.0 6.3e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59242.1 - 3.4e-11 43.1 0.1 5.6e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59243.1 - 4e-35 119.8 0.0 6.6e-35 119.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59243.1 - 5.2e-32 110.3 0.0 8.8e-32 109.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59243.1 - 9.8e-06 25.2 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_His PF13393.6 GBG59243.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase zf-C3HC4_2 PF13923.6 GBG59244.1 - 1.4e-08 34.4 4.6 1.4e-08 34.4 4.6 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 GBG59244.1 - 2.3e-08 34.2 6.5 0.0011 19.0 2.6 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-C3HC4 PF00097.25 GBG59244.1 - 3.6e-07 29.9 2.7 3.6e-07 29.9 2.7 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG59244.1 - 2e-05 24.5 5.8 8.8e-05 22.4 5.8 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-TRAF PF02176.18 GBG59244.1 - 3.5e-05 24.4 8.7 0.0004 21.0 1.3 3.8 4 1 1 5 5 5 2 TRAF-type zinc finger zf-RING_2 PF13639.6 GBG59244.1 - 0.0017 18.6 6.5 0.0017 18.6 6.5 3.7 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 GBG59244.1 - 0.0078 16.4 3.4 0.0078 16.4 3.4 3.0 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GBG59244.1 - 1.6 8.7 22.2 0.16 11.9 5.2 4.1 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-TRAF_2 PF15965.5 GBG59244.1 - 3.3 8.2 20.3 0.24 11.9 2.1 3.7 3 1 1 4 4 4 0 TRAF-like zinc-finger zf-TRAF PF02176.18 GBG59245.1 - 1e-11 45.3 33.4 1e-06 29.3 1.3 5.8 2 1 3 5 5 5 3 TRAF-type zinc finger Sina PF03145.16 GBG59245.1 - 9.7e-07 28.9 22.1 0.002 18.1 0.9 4.0 1 1 3 4 4 4 3 Seven in absentia protein family zf-C3HC4_2 PF13923.6 GBG59245.1 - 0.00034 20.4 1.2 0.00034 20.4 1.2 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG59245.1 - 0.0013 18.6 1.6 0.0013 18.6 1.6 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG59245.1 - 0.0056 16.5 4.1 0.0056 16.5 4.1 3.9 5 0 0 5 5 5 1 Prokaryotic RING finger family 4 zf-U11-48K PF05253.12 GBG59245.1 - 3.2 7.8 10.5 46 4.1 0.8 5.7 6 0 0 6 6 6 0 U11-48K-like CHHC zinc finger RVT_1 PF00078.27 GBG59246.1 - 1.7e-29 103.0 0.1 2.5e-29 102.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG59246.1 - 0.0045 17.6 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-TRAF PF02176.18 GBG59247.1 - 3.8e-08 33.9 17.1 3.2e-05 24.5 1.2 3.9 3 2 1 4 4 4 2 TRAF-type zinc finger Sina PF03145.16 GBG59247.1 - 4.7e-06 26.7 5.8 0.0073 16.3 1.6 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-TRAF_2 PF15965.5 GBG59247.1 - 0.19 12.2 13.1 2.2 8.8 1.2 3.3 2 1 1 3 3 3 0 TRAF-like zinc-finger zf-CCHC PF00098.23 GBG59247.1 - 0.36 11.0 1.9 1.1 9.5 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG59248.1 - 1.1e-10 41.7 4.3 1.7e-10 41.1 1.1 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG59248.1 - 0.0017 18.6 2.9 0.14 12.5 0.1 2.7 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG59248.1 - 0.038 14.2 0.2 0.11 12.7 0.2 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain mTERF PF02536.14 GBG59249.1 - 0.095 11.6 2.6 0.23 10.3 2.6 1.6 1 1 0 1 1 1 0 mTERF LRS4 PF10422.9 GBG59249.1 - 0.3 10.6 13.3 2.3 7.7 0.9 2.6 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 LMBR1 PF04791.16 GBG59249.1 - 1.3 7.8 4.0 1.9 7.3 4.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C3HC4_2 PF13923.6 GBG59250.1 - 2.8e-07 30.3 7.7 1e-06 28.4 7.7 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 GBG59250.1 - 5e-07 29.9 9.3 0.0013 18.7 0.1 2.9 3 0 0 3 3 2 2 Seven in absentia protein family zf-C3HC4 PF00097.25 GBG59250.1 - 1.3e-06 28.1 6.9 9e-06 25.5 6.9 2.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG59250.1 - 1.4e-05 24.9 7.2 1.4e-05 24.9 7.2 2.8 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GBG59250.1 - 1.7e-05 24.5 11.0 1.7e-05 24.5 11.0 3.0 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG59250.1 - 4.8e-05 23.3 4.1 0.00023 21.1 4.1 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GBG59250.1 - 9.5e-05 22.7 7.5 9.5e-05 22.7 7.5 3.5 3 1 0 3 3 2 1 Ring finger domain zf-TRAF PF02176.18 GBG59250.1 - 0.0002 21.9 25.3 0.0019 18.8 0.2 4.8 2 2 2 4 4 4 2 TRAF-type zinc finger Prok-RING_4 PF14447.6 GBG59250.1 - 0.00043 20.1 10.0 0.00043 20.1 10.0 3.1 4 0 0 4 4 2 1 Prokaryotic RING finger family 4 PPP4R2 PF09184.11 GBG59250.1 - 0.0046 16.6 6.3 0.15 11.6 8.2 2.0 2 0 0 2 2 2 1 PPP4R2 DUF4617 PF15395.6 GBG59250.1 - 0.0078 14.6 7.3 0.011 14.1 7.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4617) zf-C3HC4_4 PF15227.6 GBG59250.1 - 0.028 14.6 5.8 0.16 12.1 5.8 2.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DDHD PF02862.17 GBG59250.1 - 0.048 13.8 0.5 0.067 13.4 0.5 1.2 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.6 GBG59250.1 - 0.29 11.0 12.8 0.47 10.4 12.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 GBG59250.1 - 0.42 9.3 9.8 0.56 8.9 9.8 1.1 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 GBG59250.1 - 0.76 9.1 15.5 1.1 8.7 15.5 1.1 1 0 0 1 1 1 0 SDA1 SprA-related PF12118.8 GBG59250.1 - 0.78 8.8 17.7 1.1 8.3 17.7 1.1 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.12 GBG59250.1 - 1.3 8.8 10.1 1.9 8.3 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 GBG59250.1 - 1.4 8.1 8.7 1.9 7.6 8.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CCSAP PF15748.5 GBG59250.1 - 2.4 8.3 15.7 4.1 7.5 15.7 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 GBG59250.1 - 2.7 6.2 12.3 3.5 5.8 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MCU PF04678.13 GBG59250.1 - 3.2 7.8 6.1 4.7 7.3 6.1 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter zf-TRAF_2 PF15965.5 GBG59250.1 - 5.7 7.5 19.9 0.46 11.0 2.5 3.5 2 2 2 4 4 2 0 TRAF-like zinc-finger TCP PF03634.13 GBG59250.1 - 7.1 7.2 14.1 11 6.5 14.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor XPA_N PF01286.18 GBG59250.1 - 7.9 6.6 10.2 0.6 10.2 1.0 3.0 2 0 0 2 2 2 0 XPA protein N-terminal RT_RNaseH_2 PF17919.1 GBG59251.1 - 8.6e-18 64.2 0.0 1.7e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59251.1 - 2.5e-08 34.1 0.0 5.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59251.1 - 3.9e-07 29.8 0.2 5.6e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG59251.1 - 1.6 6.9 23.9 2.3 6.3 23.9 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG59251.1 - 1.6 8.1 26.6 2.3 7.6 26.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG59251.1 - 2.1 6.5 16.8 3.6 5.7 16.8 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG59251.1 - 2.6 7.3 25.4 3.7 6.8 25.4 1.1 1 0 0 1 1 1 0 BUD22 RVT_1 PF00078.27 GBG59253.1 - 1.2e-56 191.7 2.0 2.8e-27 95.7 0.1 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG59253.1 - 9.3e-07 28.3 3.0 0.16 11.0 0.0 3.3 3 0 0 3 3 3 3 Autophagy protein Apg17 LOH1CR12 PF10158.9 GBG59253.1 - 0.0022 18.0 0.6 5.2 7.1 0.0 3.4 4 0 0 4 4 4 2 Tumour suppressor protein FlxA PF14282.6 GBG59253.1 - 0.024 14.6 0.3 0.024 14.6 0.3 2.8 2 1 0 2 2 2 0 FlxA-like protein PXT1 PF15214.6 GBG59253.1 - 0.13 12.6 0.9 29 5.1 0.1 2.7 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 Peptidase_M29 PF02073.15 GBG59253.1 - 0.13 11.0 6.3 0.24 10.1 6.3 1.3 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Trans_reg_C PF00486.28 GBG59253.1 - 0.28 11.3 2.0 28 4.9 0.1 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal FAM76 PF16046.5 GBG59253.1 - 0.51 9.6 2.9 0.85 8.9 2.9 1.3 1 0 0 1 1 1 0 FAM76 protein Se-cys_synth_N PF12390.8 GBG59253.1 - 2.2 8.6 9.1 1.4e+02 2.8 0.0 5.1 4 0 0 4 4 4 0 Selenocysteine synthase N terminal Nop14 PF04147.12 GBG59254.1 - 0.63 8.2 25.5 0.75 7.9 25.5 1.0 1 0 0 1 1 1 0 Nop14-like family AAA_11 PF13086.6 GBG59254.1 - 0.73 9.6 8.5 1.2 8.9 8.5 1.3 1 0 0 1 1 1 0 AAA domain SDA1 PF05285.12 GBG59254.1 - 1.6 8.1 22.9 2.3 7.6 22.9 1.3 1 0 0 1 1 1 0 SDA1 LRR_9 PF14580.6 GBG59255.1 - 7.4e-16 58.1 8.5 1.2e-15 57.4 8.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 GBG59255.1 - 2.2e-13 50.2 52.1 1.6e-05 25.2 6.6 3.7 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG59255.1 - 4.3e-07 29.6 26.3 0.00096 18.9 3.7 3.2 2 1 0 3 3 3 2 Leucine rich repeat Latarcin PF10279.9 GBG59255.1 - 0.061 13.7 0.5 0.25 11.8 0.5 2.1 1 1 0 1 1 1 0 Latarcin precursor LRR_1 PF00560.33 GBG59255.1 - 0.34 11.6 8.8 56 4.9 0.3 4.3 3 1 0 3 3 3 0 Leucine Rich Repeat DUF1682 PF07946.14 GBG59255.1 - 1.2 8.3 4.0 3.3 6.8 4.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) rRNA_methylase PF06962.12 GBG59256.1 - 1.3e-40 138.6 0.0 1.9e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Putative rRNA methylase Methyltransf_31 PF13847.6 GBG59256.1 - 0.16 11.7 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Macoilin PF09726.9 GBG59256.1 - 2.5 6.6 6.1 3.5 6.1 6.1 1.2 1 0 0 1 1 1 0 Macoilin family LRR_4 PF12799.7 GBG59257.1 - 4.6e-18 65.0 51.0 3.2e-06 27.4 6.7 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG59257.1 - 1e-08 34.8 25.3 0.00021 21.0 3.7 2.8 1 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 GBG59257.1 - 7.5e-08 32.1 9.1 1.3e-07 31.3 9.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 GBG59257.1 - 0.05 14.2 14.6 5.9 7.9 0.1 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 GBG59257.1 - 0.35 11.0 14.7 3.9 7.8 0.2 4.5 4 0 0 4 4 4 0 Leucine Rich repeat PDCD2_C PF04194.13 GBG59258.1 - 0.04 14.0 3.2 0.042 13.9 3.2 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Radial_spoke_3 PF06098.11 GBG59258.1 - 0.18 11.1 15.5 0.035 13.4 11.9 1.6 2 0 0 2 2 2 0 Radial spoke protein 3 Casc1_N PF15927.5 GBG59258.1 - 0.25 11.0 16.1 0.45 10.2 16.1 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus RPN2_C PF18004.1 GBG59258.1 - 7.5 6.5 17.4 7.1 6.5 0.1 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ribosomal_L28e PF01778.17 GBG59259.1 - 6.6e-39 133.2 2.3 6.6e-39 133.2 2.3 2.3 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 GBG59259.1 - 2.2e-28 98.8 24.3 2.2e-28 98.8 24.3 3.0 1 1 2 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 GBG59259.1 - 5.4e-05 22.7 28.1 7e-05 22.4 28.1 1.2 1 0 0 1 1 1 1 BUD22 SAPS PF04499.15 GBG59259.1 - 3.1 6.5 15.7 3.9 6.1 15.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 GBG59260.1 - 7.6 4.5 43.2 8 4.4 43.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG59260.1 - 10 5.5 27.3 12 5.3 27.3 1.1 1 0 0 1 1 1 0 SDA1 Glyco_hydro_20 PF00728.22 GBG59261.1 - 1.4e-78 264.8 0.1 3.1e-78 263.7 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GBG59261.1 - 4.4e-19 69.5 0.1 1.2e-18 68.1 0.0 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_97 PF10566.9 GBG59261.1 - 0.038 13.3 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 GHL6 PF14871.6 GBG59261.1 - 0.084 13.0 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Glyco_hydro_20 PF00728.22 GBG59262.1 - 6.5e-81 272.5 1.0 1.9e-80 270.9 1.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GBG59262.1 - 1.6e-19 70.9 0.2 5.4e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_97 PF10566.9 GBG59262.1 - 0.049 12.9 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 DUF3991 PF13154.6 GBG59262.1 - 0.096 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) ATP-synt_B PF00430.18 GBG59263.1 - 3.5 7.7 18.7 3.2 7.9 17.3 1.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) LYRIC PF15686.5 GBG59263.1 - 6.3 6.2 16.4 8.7 5.8 16.3 1.3 1 1 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Lenti_VIF_2 PF07401.12 GBG59264.1 - 0.56 9.5 2.6 0.33 10.3 0.5 1.6 2 0 0 2 2 2 0 Bovine Lentivirus VIF protein zf-CCHC PF00098.23 GBG59265.1 - 5.3e-07 29.4 4.0 9.5e-07 28.6 4.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG59265.1 - 0.012 15.5 2.2 0.03 14.3 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG59265.1 - 0.27 11.0 0.8 0.52 10.1 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle MMADHC PF10229.9 GBG59265.1 - 2.3 7.9 6.6 3.2 7.4 6.6 1.1 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein MbeB_N PF04837.12 GBG59266.1 - 0.14 12.5 0.5 0.36 11.2 0.5 1.7 1 0 0 1 1 1 0 MbeB-like, N-term conserved region SUIM_assoc PF16619.5 GBG59266.1 - 0.22 11.6 5.6 0.055 13.5 1.7 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPR_12 PF13424.6 GBG59266.1 - 0.3 11.4 2.0 3.9 7.8 0.1 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG59266.1 - 8.2 6.4 6.3 8.4 6.4 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fer2 PF00111.27 GBG59267.1 - 2.8e-12 46.4 0.2 5.6e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CTD PF12815.7 GBG59267.1 - 0.06 13.9 8.0 0.093 13.3 8.0 1.3 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 SIL1 PF16782.5 GBG59267.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 DUF4614 PF15391.6 GBG59268.1 - 0.045 13.8 1.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) PaREP1 PF05942.11 GBG59268.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.8 2 1 0 2 2 2 0 Archaeal PaREP1/PaREP8 family LCD1 PF09798.9 GBG59268.1 - 0.51 8.8 3.2 0.5 8.8 3.2 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein ATP-synt_B PF00430.18 GBG59268.1 - 7.5 6.7 18.5 1.9 8.6 5.7 3.2 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) DUF3742 PF12553.8 GBG59269.1 - 6 7.0 14.7 0.47 10.6 9.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) DUF460 PF04312.13 GBG59270.1 - 0.015 15.0 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) LepA_C PF06421.12 GBG59271.1 - 7.3e-48 161.2 1.4 1.3e-47 160.4 1.4 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 GBG59271.1 - 2.7e-45 154.3 0.0 1e-25 90.4 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GBG59271.1 - 7.2e-23 80.4 0.0 1.5e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GBG59271.1 - 2.2e-06 27.9 0.3 5e-06 26.8 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GBG59271.1 - 8.4e-05 22.6 0.0 0.00025 21.1 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 GBG59271.1 - 0.0093 15.8 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Dehydrin PF00257.19 GBG59271.1 - 0.034 14.7 0.7 0.034 14.7 0.7 1.9 2 0 0 2 2 2 0 Dehydrin CIAPIN1 PF05093.13 GBG59271.1 - 0.096 13.2 0.1 0.61 10.6 0.0 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Tfb4 PF03850.14 GBG59272.1 - 1.1 8.7 3.0 1.8 8.0 3.0 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 RR_TM4-6 PF06459.12 GBG59272.1 - 2.5 7.9 11.3 4.2 7.1 11.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 GBG59272.1 - 8.4 5.1 10.0 13 4.4 10.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIE PF07228.12 GBG59274.1 - 1.5e-10 41.4 0.0 2.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GBG59274.1 - 3e-07 30.3 0.0 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GBG59274.1 - 7.3e-06 25.8 0.0 2.2e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Chromo PF00385.24 GBG59275.1 - 5.2e-12 45.5 0.0 9.2e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain cEGF PF12662.7 GBG59275.1 - 0.13 12.2 0.3 0.29 11.1 0.3 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like WD40 PF00400.32 GBG59276.1 - 5.3e-36 122.0 15.4 4.7e-07 30.4 0.3 8.2 7 1 0 7 7 7 6 WD domain, G-beta repeat Bromodomain PF00439.25 GBG59276.1 - 6.5e-07 29.3 0.1 1.2e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain ANAPC4_WD40 PF12894.7 GBG59276.1 - 0.0011 19.2 0.1 22 5.5 0.0 4.4 2 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Agenet PF05641.12 GBG59276.1 - 0.034 14.6 0.7 0.12 12.8 0.7 2.0 1 0 0 1 1 1 0 Agenet domain Auxin_resp PF06507.13 GBG59276.1 - 0.069 13.4 0.2 0.18 12.1 0.2 1.6 1 0 0 1 1 1 0 Auxin response factor DUF5352 PF17303.2 GBG59277.1 - 0.15 11.9 0.7 0.31 10.9 0.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5352) PPL5 PF18168.1 GBG59277.1 - 1.4 8.1 7.8 2.8 7.2 7.8 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Rxt3 PF08642.10 GBG59277.1 - 1.5 9.6 4.5 0.83 10.4 1.3 2.1 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 RP-C_C PF11800.8 GBG59277.1 - 1.7 8.7 10.0 0.16 12.0 5.3 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region RT_RNaseH_2 PF17919.1 GBG59278.1 - 1.9e-34 117.6 0.0 4.9e-34 116.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59278.1 - 3.9e-27 94.6 0.6 1.8e-26 92.5 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59278.1 - 1.2e-25 90.4 0.0 2e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG59278.1 - 5.3e-06 26.2 0.0 9.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59278.1 - 0.032 14.9 0.0 0.072 13.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Tho1_MOS11_C PF18592.1 GBG59278.1 - 0.11 12.3 1.3 0.78 9.6 1.0 2.5 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain gag-asp_proteas PF13975.6 GBG59278.1 - 0.2 12.2 0.0 0.46 11.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CENP-Q PF13094.6 GBG59278.1 - 0.45 10.7 5.8 1.3 9.2 5.8 1.8 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Kinesin PF00225.23 GBG59279.1 - 8.5e-97 324.0 0.2 1.4e-96 323.4 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG59279.1 - 3.8e-25 88.6 0.0 8.3e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Asp_protease_2 PF13650.6 GBG59279.1 - 0.002 18.7 0.0 0.011 16.4 0.0 2.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG59279.1 - 0.0021 18.3 0.3 0.0082 16.4 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG59279.1 - 0.0034 17.9 0.0 0.018 15.6 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease BrnA_antitoxin PF14384.6 GBG59279.1 - 0.022 15.2 0.0 0.078 13.5 0.0 2.0 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system DUF1319 PF07028.11 GBG59279.1 - 1.6 9.0 6.0 0.45 10.8 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) Asp_protease_2 PF13650.6 GBG59280.1 - 0.0012 19.5 0.0 0.0074 16.9 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG59280.1 - 0.0018 18.5 0.4 0.0055 17.0 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG59280.1 - 0.0021 18.6 0.0 0.012 16.2 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease BrnA_antitoxin PF14384.6 GBG59280.1 - 0.016 15.7 0.0 0.052 14.0 0.0 1.9 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system BUD22 PF09073.10 GBG59281.1 - 0.53 9.6 37.6 0.7 9.2 37.6 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 GBG59281.1 - 1.3 8.3 15.4 2 7.7 15.4 1.4 1 0 0 1 1 1 0 NOA36 protein SepSecS PF05889.13 GBG59281.1 - 1.9 7.1 4.9 3.2 6.3 4.9 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Kinesin PF00225.23 GBG59282.1 - 8.8e-98 327.3 0.2 1.2e-97 326.9 0.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG59282.1 - 5.5e-26 91.3 0.0 1.3e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF1319 PF07028.11 GBG59282.1 - 0.04 14.1 0.3 0.089 13.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) RVT_1 PF00078.27 GBG59283.1 - 1.7e-30 106.2 0.1 3.3e-30 105.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59283.1 - 5.5e-30 103.4 0.0 1.2e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59283.1 - 9.2e-26 90.2 0.0 1.8e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG59284.1 - 2.2e-27 95.8 0.2 4.1e-27 94.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59284.1 - 1.8e-08 34.0 0.1 4.2e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 GBG59285.1 - 3.1e-58 197.2 0.0 3.9e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG59285.1 - 3.2e-42 144.6 0.0 4.2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG59285.1 - 1.9e-05 23.7 0.0 3.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GBG59285.1 - 9.3e-05 21.9 0.0 0.0003 20.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GBG59285.1 - 0.0027 16.7 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GBG59285.1 - 0.0048 16.8 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GBG59285.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 GBG59285.1 - 0.041 13.2 0.0 0.096 12.0 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAP206 PF12018.8 GBG59286.1 - 2.7e-37 128.8 0.4 2.7e-37 128.8 0.4 2.1 2 1 0 2 2 2 1 Domain of unknown function YHS PF04945.13 GBG59286.1 - 0.005 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 YHS domain Mei5_like PF17021.5 GBG59286.1 - 0.058 13.4 0.8 0.15 12.1 0.8 1.6 1 0 0 1 1 1 0 Putative double-strand recombination repair-like SF3A3 PF16837.5 GBG59286.1 - 0.12 12.9 0.1 5.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 TBCC_N PF16752.5 GBG59286.1 - 1.8 9.0 8.5 0.2 12.1 3.5 2.0 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DDRGK PF09756.9 GBG59287.1 - 0.17 11.5 14.1 0.3 10.6 14.1 1.4 1 0 0 1 1 1 0 DDRGK domain Med2 PF11214.8 GBG59287.1 - 0.38 10.9 4.6 1.3 9.2 4.6 1.9 1 1 0 1 1 1 0 Mediator complex subunit 2 RVT_1 PF00078.27 GBG59288.1 - 1.2e-20 74.0 0.1 2.2e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAPS PF04499.15 GBG59288.1 - 0.17 10.6 2.8 0.21 10.3 2.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 GBG59288.1 - 0.49 9.7 23.7 0.66 9.2 23.7 1.1 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 GBG59288.1 - 0.76 8.9 14.6 1.1 8.4 14.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cwf_Cwc_15 PF04889.12 GBG59288.1 - 1.4 8.6 19.3 2.1 8.0 19.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG59288.1 - 1.9 7.8 25.2 2.5 7.5 25.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG59288.1 - 2.1 6.4 24.2 2.8 6.0 24.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG59288.1 - 2.6 6.2 16.3 3.5 5.8 16.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 GBG59288.1 - 2.8 8.1 6.7 5.6 7.1 6.7 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal zf-CCHC PF00098.23 GBG59289.1 - 0.00095 19.1 9.1 0.0016 18.4 9.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG59289.1 - 0.96 9.3 4.2 2.7 7.9 4.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG59289.1 - 1.1 9.1 3.4 2.2 8.1 3.4 1.5 1 0 0 1 1 1 0 Zinc knuckle MAP7 PF05672.11 GBG59289.1 - 2.8 7.6 35.8 0.063 13.0 27.3 2.0 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Pectinesterase PF01095.19 GBG59290.1 - 2.2e-66 223.6 5.5 3.3e-66 223.0 5.5 1.2 1 0 0 1 1 1 1 Pectinesterase PsbP PF01789.16 GBG59291.1 - 3.9e-26 92.0 0.0 2.5e-23 82.9 0.0 2.3 2 0 0 2 2 2 2 PsbP Pectinesterase PF01095.19 GBG59293.1 - 1.7e-61 207.5 2.3 2.1e-61 207.3 2.3 1.0 1 0 0 1 1 1 1 Pectinesterase 60KD_IMP PF02096.20 GBG59295.1 - 6.2 6.7 5.7 10 6.0 5.7 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein SAD_SRA PF02182.17 GBG59297.1 - 2.3e-41 141.1 0.0 7.9e-41 139.4 0.0 1.9 2 0 0 2 2 2 1 SAD/SRA domain SET PF00856.28 GBG59297.1 - 4.7e-20 72.6 0.0 1.2e-19 71.3 0.0 1.8 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 GBG59297.1 - 2e-17 63.8 0.9 2e-17 63.8 0.9 1.9 2 0 0 2 2 2 1 Pre-SET motif Oleosin PF01277.17 GBG59298.1 - 8.2e-11 41.7 29.1 1.6e-09 37.5 13.5 3.1 2 1 0 2 2 2 2 Oleosin DUF3318 PF11780.8 GBG59298.1 - 0.32 11.0 3.7 0.25 11.3 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3318) TPR_8 PF13181.6 GBG59299.1 - 5.5e-08 32.4 0.7 0.00015 21.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG59299.1 - 5.6e-08 32.3 3.5 3e-05 23.7 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG59299.1 - 2.2e-06 27.3 3.2 0.00054 19.9 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG59299.1 - 3.5e-05 23.5 0.5 0.087 12.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG59299.1 - 4.9e-05 23.5 0.2 9.1e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG59299.1 - 0.0041 17.0 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 GBG59299.1 - 0.0065 16.6 0.1 3.2 8.0 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG59299.1 - 0.032 14.8 0.2 5 8.0 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG59300.1 - 2.7e-14 53.2 0.0 4.4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59300.1 - 3e-10 40.0 0.1 6.2e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG59300.1 - 1.8e-05 24.6 3.2 3.1e-05 23.8 3.2 1.4 1 0 0 1 1 1 1 Zinc knuckle YL1 PF05764.13 GBG59300.1 - 0.013 15.6 65.4 0.25 11.4 27.5 2.5 2 0 0 2 2 2 0 YL1 nuclear protein zf-CCHC_2 PF13696.6 GBG59300.1 - 0.035 13.9 4.1 0.061 13.2 4.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG59301.1 - 3.1e-06 27.0 1.0 6.6e-06 26.0 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG59301.1 - 6.4e-05 23.4 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG59301.1 - 0.001 18.8 3.1 0.0024 17.7 2.5 1.9 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG59301.1 - 0.0013 19.0 0.3 0.0048 17.1 0.3 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG59301.1 - 0.0078 16.8 0.0 0.018 15.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Gag_p24 PF00607.20 GBG59301.1 - 0.03 14.2 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) RVP_2 PF08284.11 GBG59301.1 - 0.05 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease COX6B PF02297.17 GBG59302.1 - 1.9e-17 63.2 7.5 3.2e-17 62.5 7.5 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 GBG59302.1 - 0.00094 19.3 0.2 0.0019 18.3 0.2 1.5 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 GBG59302.1 - 0.062 13.3 2.6 0.11 12.5 2.6 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TRAP_alpha PF03896.16 GBG59302.1 - 0.094 11.9 3.6 0.11 11.7 3.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HOCHOB PF17943.1 GBG59302.1 - 0.13 13.0 0.5 0.24 12.1 0.5 1.4 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox Nop53 PF07767.11 GBG59302.1 - 4.8 6.5 8.3 6 6.1 8.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TPR_12 PF13424.6 GBG59303.1 - 0.00037 20.7 0.9 0.00063 20.0 0.9 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG59303.1 - 0.00055 19.8 0.2 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG59303.1 - 0.003 17.7 0.2 0.16 12.3 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG59303.1 - 0.0049 16.6 0.3 0.88 9.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat AdoHcyase PF05221.17 GBG59304.1 - 6.6e-144 478.6 0.0 7.5e-144 478.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GBG59304.1 - 2.3e-82 274.8 1.8 3.6e-82 274.2 1.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GBG59304.1 - 2.1e-06 27.2 0.3 3.9e-06 26.4 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GBG59304.1 - 0.00054 19.6 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 GBG59304.1 - 0.0014 18.8 0.1 0.0037 17.5 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 GBG59304.1 - 0.035 14.2 0.3 0.1 12.6 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 GBG59304.1 - 0.12 12.3 0.4 0.3 10.9 0.2 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RVT_1 PF00078.27 GBG59306.1 - 1.4e-19 70.6 0.0 2.7e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG59306.1 - 1.1e-12 48.1 0.1 3.5e-12 46.6 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG59307.1 - 5.1e-30 104.6 0.0 7.7e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG59307.1 - 2.1e-08 34.0 0.0 3.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG59307.1 - 6.8e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG59307.1 - 0.00096 19.8 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59307.1 - 0.02 15.5 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG59308.1 - 2.2e-27 96.0 0.1 3.4e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG59308.1 - 1.7e-07 31.8 0.0 6.2e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG59308.1 - 8.5e-07 28.8 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG59308.1 - 1.7e-06 28.5 0.0 5.4e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG59308.1 - 0.00035 20.4 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF1904 PF08921.11 GBG59308.1 - 0.027 14.8 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) DDE_Tnp_4 PF13359.6 GBG59310.1 - 5e-25 88.0 0.0 1.9e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG59310.1 - 9.1e-13 48.3 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG59310.1 - 1.4e-05 24.8 1.0 0.032 13.9 0.0 3.1 3 0 0 3 3 3 2 Transposase DDE domain DUF4376 PF14301.6 GBG59310.1 - 0.047 14.0 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) RVT_1 PF00078.27 GBG59311.1 - 2.6e-55 187.3 2.1 2.1e-27 96.1 0.3 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59311.1 - 6.5e-37 126.0 0.5 5.9e-26 90.8 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59311.1 - 7.4e-35 119.0 0.3 1.7e-30 105.0 0.0 3.6 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59311.1 - 4.8e-31 106.7 4.0 1.7e-15 56.8 1.3 3.4 3 0 0 3 3 3 2 Integrase zinc binding domain rve PF00665.26 GBG59311.1 - 1.9e-21 76.5 0.0 3.2e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain Asp_protease_2 PF13650.6 GBG59311.1 - 5.3e-07 30.2 0.0 1.4e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59311.1 - 1.8e-06 28.4 0.0 4.6e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59311.1 - 9.2e-06 25.5 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG59311.1 - 7.2e-05 22.9 0.9 0.087 13.1 1.7 2.9 2 0 0 2 2 2 2 H2C2 zinc finger Asp_protease PF09668.10 GBG59311.1 - 0.00029 20.6 0.0 0.0008 19.2 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG59311.1 - 0.037 14.3 2.2 0.13 12.5 0.2 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein ZapB PF06005.12 GBG59311.1 - 0.21 12.0 0.1 0.21 12.0 0.1 3.9 5 0 0 5 5 4 0 Cell division protein ZapB DUF1634 PF07843.11 GBG59313.1 - 0.057 13.5 0.2 0.14 12.3 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1634) TRIQK PF15168.6 GBG59313.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.7 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family DUF3782 PF12644.7 GBG59314.1 - 0.23 11.7 5.4 0.5 10.6 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) HSP70 PF00012.20 GBG59314.1 - 0.28 9.3 5.1 0.37 8.9 5.1 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF3782 PF12644.7 GBG59315.1 - 0.079 13.1 5.8 0.23 11.6 5.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) GBP_C PF02841.14 GBG59315.1 - 0.18 11.2 8.3 0.23 10.8 8.3 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain SOBP PF15279.6 GBG59316.1 - 0.23 12.1 11.5 0.3 11.6 11.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RT_RNaseH PF17917.1 GBG59317.1 - 7.9e-13 48.6 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59317.1 - 4.8e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59317.1 - 0.043 14.1 3.1 0.6 10.4 0.3 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein 2OG-FeII_Oxy_2 PF13532.6 GBG59318.1 - 8.5e-37 127.2 0.0 6.9e-35 121.0 0.0 2.9 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily DUF659 PF04937.15 GBG59319.1 - 0.0006 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59319.1 - 0.0029 17.3 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nop14 PF04147.12 GBG59319.1 - 0.28 9.4 35.9 0.44 8.7 35.9 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG59319.1 - 2.1 7.6 37.9 3.6 6.8 37.9 1.3 1 0 0 1 1 1 0 BUD22 GPCR_chapero_1 PF11904.8 GBG59319.1 - 8.7 5.7 12.0 14 5.0 12.0 1.3 1 0 0 1 1 1 0 GPCR-chaperone Ribonuc_L-PSP PF01042.21 GBG59320.1 - 4.2e-38 130.1 0.0 6.3e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP RPN13_C PF16550.5 GBG59320.1 - 0.055 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 UCH-binding domain RVT_1 PF00078.27 GBG59321.1 - 6.1e-10 39.0 0.0 9.6e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG59321.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Cwf_Cwc_15 PF04889.12 GBG59321.1 - 1.9 8.2 13.9 10 5.8 0.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TRAM_LAG1_CLN8 PF03798.16 GBG59323.1 - 1.8e-20 73.5 0.1 1.8e-20 73.5 0.1 1.8 2 0 0 2 2 2 1 TLC domain DUF2700 PF10912.8 GBG59323.1 - 0.078 13.0 1.9 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2700) Presenilin PF01080.17 GBG59324.1 - 1.5 7.5 9.1 2.2 7.0 9.1 1.3 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 GBG59324.1 - 1.9 7.4 8.6 2.5 7.0 8.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.12 GBG59324.1 - 3.3 6.7 8.8 4.7 6.2 8.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Sel1 PF08238.12 GBG59325.1 - 1.1e-14 54.6 16.5 9e-06 26.2 0.4 6.4 6 0 0 6 6 6 3 Sel1 repeat Tai4 PF16695.5 GBG59325.1 - 0.084 13.4 0.2 0.36 11.4 0.2 2.1 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein TPR_8 PF13181.6 GBG59325.1 - 0.56 10.6 3.4 24 5.5 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Integrase_H2C2 PF17921.1 GBG59326.1 - 0.0036 17.4 0.1 0.0067 16.5 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain CDC45 PF02724.14 GBG59326.1 - 1.3 7.2 17.3 2 6.6 17.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG59326.1 - 1.4 7.0 22.3 1.9 6.6 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG59326.1 - 1.4 8.2 22.3 1.9 7.9 22.3 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG59326.1 - 2.4 7.6 14.8 3.5 7.1 14.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 GBG59326.1 - 6 6.1 26.0 9.9 5.4 26.0 1.3 1 0 0 1 1 1 0 BUD22 COX16 PF14138.6 GBG59327.1 - 0.033 14.7 0.2 0.091 13.3 0.2 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 CDC45 PF02724.14 GBG59327.1 - 0.065 11.5 3.3 0.095 11.0 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Trp_oprn_chp PF09534.10 GBG59327.1 - 0.1 12.4 1.5 0.13 12.1 0.3 1.7 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Kazal_2 PF07648.15 GBG59327.1 - 1.6 8.9 5.8 0.21 11.8 0.7 2.0 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Nop14 PF04147.12 GBG59327.1 - 7.6 4.6 9.8 11 4.0 9.8 1.2 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 GBG59329.1 - 0.0017 18.2 10.2 0.0021 18.0 10.2 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein Presenilin PF01080.17 GBG59329.1 - 0.0021 16.9 7.5 0.0026 16.6 7.5 1.2 1 0 0 1 1 1 1 Presenilin RR_TM4-6 PF06459.12 GBG59329.1 - 0.014 15.3 15.6 0.017 14.9 15.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG59329.1 - 0.014 14.8 37.8 0.016 14.6 37.8 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 GBG59329.1 - 0.02 13.9 7.1 0.024 13.6 7.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PPL5 PF18168.1 GBG59329.1 - 0.032 13.5 9.3 0.041 13.2 9.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 SAPS PF04499.15 GBG59329.1 - 0.032 13.0 10.4 0.032 13.0 10.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UPF0242 PF06785.11 GBG59329.1 - 0.036 14.2 8.3 0.044 13.9 8.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2828 PF11443.8 GBG59329.1 - 0.047 11.8 1.9 0.059 11.5 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SID-1_RNA_chan PF13965.6 GBG59329.1 - 0.048 12.1 0.9 0.056 11.9 0.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 GBG59329.1 - 0.13 11.2 4.1 0.13 11.2 4.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Nop14 PF04147.12 GBG59329.1 - 0.2 9.8 44.1 0.25 9.5 44.1 1.0 1 0 0 1 1 1 0 Nop14-like family O-antigen_lig PF13425.6 GBG59329.1 - 0.37 9.5 2.0 0.51 9.1 2.0 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PIP5K PF01504.18 GBG59329.1 - 0.49 9.6 3.0 0.55 9.4 3.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase FGF-BP1 PF06473.12 GBG59329.1 - 0.59 9.9 9.8 0.79 9.5 9.8 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Mpp10 PF04006.12 GBG59329.1 - 0.65 8.4 40.1 0.79 8.1 40.1 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF5427 PF10310.9 GBG59329.1 - 0.7 8.8 17.5 0.83 8.5 17.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF2201_N PF13203.6 GBG59329.1 - 1.2 8.6 8.6 1.5 8.3 8.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Tub_N PF16322.5 GBG59329.1 - 1.6 9.1 25.6 2.5 8.5 25.6 1.3 1 0 0 1 1 1 0 Tubby N-terminal Na_trans_assoc PF06512.13 GBG59329.1 - 2.2 8.5 26.0 3.2 8.0 26.0 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2151 PF10221.9 GBG59329.1 - 2.5 6.6 10.7 2.6 6.5 10.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Coilin_N PF15862.5 GBG59329.1 - 2.5 7.9 12.0 3.4 7.5 12.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus PA26 PF04636.13 GBG59329.1 - 3.1 6.6 6.3 3.4 6.5 6.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) AAA_11 PF13086.6 GBG59329.1 - 3.2 7.5 7.3 3.6 7.3 7.3 1.1 1 0 0 1 1 1 0 AAA domain CobT PF06213.12 GBG59329.1 - 3.4 7.0 42.6 4.8 6.5 42.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Caldesmon PF02029.15 GBG59329.1 - 5.9 5.5 35.1 7.1 5.3 35.1 1.0 1 0 0 1 1 1 0 Caldesmon BUD22 PF09073.10 GBG59329.1 - 6.8 5.9 38.2 8.2 5.6 38.2 1.0 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 GBG59329.1 - 7.8 6.8 22.1 12 6.2 22.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4045 PF13254.6 GBG59329.1 - 9.9 5.7 13.4 12 5.4 13.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RT_RNaseH PF17917.1 GBG59330.1 - 8.3e-26 90.3 0.0 1.7e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59330.1 - 2.5e-25 89.3 0.1 4.1e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59330.1 - 3.4e-24 84.8 0.0 6.9e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59330.1 - 6.3e-16 58.6 0.0 1.7e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG59330.1 - 8.5e-08 32.2 0.1 2e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG59330.1 - 0.0011 19.1 0.0 0.0031 17.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG59331.1 - 1.1e-62 211.5 0.2 1.6e-35 122.7 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59331.1 - 5.1e-31 106.7 0.0 1.5e-30 105.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59331.1 - 2.7e-30 104.7 0.0 5.9e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Lipase_3 PF01764.25 GBG59331.1 - 5e-28 97.7 0.1 1.6e-27 96.1 0.1 1.9 1 0 0 1 1 1 1 Lipase (class 3) Integrase_H2C2 PF17921.1 GBG59331.1 - 2.9e-16 59.3 1.1 7.3e-16 58.0 1.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG59331.1 - 1.3e-05 25.0 0.0 0.0001 22.1 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59331.1 - 4.3e-05 24.1 0.0 0.0018 18.9 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59331.1 - 0.00019 21.9 0.0 0.088 13.4 0.0 2.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Esterase PF00756.20 GBG59331.1 - 0.0071 16.0 0.0 0.03 14.0 0.0 2.0 2 0 0 2 2 2 1 Putative esterase rve PF00665.26 GBG59331.1 - 0.013 15.7 0.0 0.041 14.1 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Hydrolase_4 PF12146.8 GBG59331.1 - 0.016 14.5 0.0 0.058 12.7 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 zf-CCHC_4 PF14392.6 GBG59331.1 - 0.027 14.2 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG59331.1 - 0.24 11.7 8.3 4.4 7.6 0.0 3.8 4 0 0 4 4 2 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG59331.1 - 0.73 10.0 3.2 2.2 8.5 3.2 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG59331.1 - 1.3 8.9 5.7 0.95 9.4 3.2 2.2 2 0 0 2 2 2 0 Zinc knuckle HGTP_anticodon2 PF12745.7 GBG59333.1 - 0.73 9.3 7.9 2.9 7.3 7.9 2.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs HC2 PF07382.11 GBG59334.1 - 1.6 8.7 19.5 2.4 8.2 19.5 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 RVT_1 PF00078.27 GBG59335.1 - 1e-60 205.0 0.2 2.9e-30 105.4 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TIMELESS PF04821.14 GBG59335.1 - 3.2e-51 174.2 16.3 6.7e-51 173.2 0.2 5.0 5 0 0 5 5 5 2 Timeless protein TIMELESS_C PF05029.13 GBG59335.1 - 1e-07 31.5 0.2 1e-07 31.5 0.2 6.1 5 1 1 6 6 6 1 Timeless protein C terminal region RT_RNaseH_2 PF17919.1 GBG59335.1 - 0.0032 17.5 0.3 1.8 8.6 0.1 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase DUF373 PF04123.13 GBG59336.1 - 0.24 10.8 6.5 0.33 10.3 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) LMF1 PF06762.14 GBG59336.1 - 1.3 8.1 10.4 1.6 7.8 10.4 1.1 1 0 0 1 1 1 0 Lipase maturation factor DUF2663 PF10864.8 GBG59336.1 - 1.4 9.3 13.2 1.1 9.7 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Tetraspanin PF00335.20 GBG59337.1 - 0.0018 18.1 1.0 0.0025 17.6 1.0 1.2 1 0 0 1 1 1 1 Tetraspanin family tRNA_anti-like PF12869.7 GBG59337.1 - 0.23 11.1 0.2 0.35 10.5 0.2 1.3 1 0 0 1 1 1 0 tRNA_anti-like Abhydrolase_1 PF00561.20 GBG59338.1 - 5.1e-16 59.1 0.5 8.1e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG59338.1 - 4.6e-11 42.4 0.1 1.1e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG59338.1 - 1.2e-09 39.1 12.8 3.4e-07 31.1 12.8 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 GBG59338.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.10 GBG59338.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein zf-CCHC PF00098.23 GBG59339.1 - 0.1 12.7 4.4 0.21 11.8 4.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG59339.1 - 0.68 9.8 3.6 2 8.3 3.6 1.8 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG59339.1 - 7.6 6.9 8.5 14 6.0 0.2 3.9 4 0 0 4 4 4 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG59340.1 - 5.6e-35 119.4 0.0 1.3e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59340.1 - 1.4e-30 105.6 0.1 3.4e-30 104.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG59340.1 - 0.0013 18.4 1.2 0.0036 17.0 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) DUF1904 PF08921.11 GBG59340.1 - 0.054 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) Response_reg PF00072.24 GBG59341.1 - 1.4e-20 73.5 2.4 2.4e-20 72.8 0.1 2.7 3 0 0 3 3 3 1 Response regulator receiver domain HATPase_c PF02518.26 GBG59341.1 - 2.2e-19 70.0 1.8 3e-14 53.5 0.0 3.4 4 0 0 4 4 4 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pribosyltran PF00156.27 GBG59341.1 - 8.9e-05 22.1 3.0 0.47 9.9 0.0 3.9 4 0 0 4 4 4 3 Phosphoribosyl transferase domain Leg1 PF05612.12 GBG59341.1 - 0.18 10.9 0.1 18 4.3 0.0 2.2 2 0 0 2 2 2 0 Leg1 RVT_1 PF00078.27 GBG59343.1 - 5.6e-34 117.6 0.1 9.1e-34 116.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59343.1 - 2.6e-30 104.4 0.0 7.4e-30 102.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59343.1 - 4e-30 104.2 0.0 1.1e-29 102.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59343.1 - 1.7e-06 27.9 0.0 3.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59343.1 - 3.4e-05 24.4 0.0 9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59343.1 - 0.00063 20.2 0.1 0.002 18.6 0.1 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG59343.1 - 0.00065 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG59343.1 - 0.076 12.8 0.0 1.2 9.0 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease DRY_EERY PF09750.9 GBG59343.1 - 1.2 9.4 7.5 15 5.9 0.0 2.7 2 0 0 2 2 2 0 Alternative splicing regulator DDE_Tnp_4 PF13359.6 GBG59344.1 - 3.9e-24 85.1 0.0 1.1e-23 83.7 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG59344.1 - 4.4e-12 46.0 0.0 8.2e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG59344.1 - 0.00014 21.6 1.9 0.0023 17.6 0.0 2.9 3 0 0 3 3 3 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG59344.1 - 0.047 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG59345.1 - 0.00013 22.3 3.8 0.00024 21.4 3.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG59345.1 - 0.16 12.3 1.6 0.39 11.1 1.6 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SR-25 PF10500.9 GBG59346.1 - 0.04 13.5 4.7 0.045 13.4 4.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pec_lyase_C PF00544.19 GBG59347.1 - 1.1e-20 74.2 0.1 1.4e-20 73.8 0.1 1.1 1 0 0 1 1 1 1 Pectate lyase EKR PF10371.9 GBG59347.1 - 0.014 15.2 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function REV PF00424.18 GBG59348.1 - 1.9 8.5 4.3 0.67 10.0 0.5 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Actin PF00022.19 GBG59349.1 - 6.6e-105 351.0 0.0 5.7e-64 216.2 0.0 2.7 1 1 1 2 2 2 2 Actin RVT_1 PF00078.27 GBG59350.1 - 1.2e-31 110.0 0.1 2e-31 109.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG59350.1 - 8e-07 29.5 0.0 2.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59350.1 - 0.00013 22.5 0.0 0.00053 20.6 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG59350.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG59350.1 - 0.031 14.1 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease HepII_C PF18675.1 GBG59350.1 - 0.072 13.2 0.0 7.8 6.7 0.0 2.7 2 0 0 2 2 2 0 Heparinase II C-terminal domain Peptidase_S64 PF08192.11 GBG59350.1 - 0.16 10.5 1.2 0.24 9.9 1.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DivIC PF04977.15 GBG59350.1 - 1.1 9.1 3.8 0.47 10.2 0.8 1.9 2 0 0 2 2 2 0 Septum formation initiator RAP1 PF07218.11 GBG59350.1 - 4.9 5.3 5.5 7 4.8 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM199X PF15814.5 GBG59350.1 - 5.7 5.9 9.2 11 5.0 9.2 1.4 1 0 0 1 1 1 0 Protein family FAM199X DEAD PF00270.29 GBG59351.1 - 1.2e-45 155.5 0.0 2e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG59351.1 - 1.3e-23 83.5 0.0 5.3e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GBG59351.1 - 3.5e-16 59.2 0.0 5.9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GBG59351.1 - 2.3e-05 24.4 0.5 0.00015 21.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 GBG59351.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain CBM53 PF16760.5 GBG59352.1 - 0.0015 19.1 0.0 0.0042 17.6 0.0 1.8 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) AP2 PF00847.20 GBG59354.1 - 1.9e-08 34.4 4.1 0.0014 18.8 0.1 3.4 3 0 0 3 3 3 2 AP2 domain FR47 PF08445.10 GBG59354.1 - 0.0095 15.9 0.0 1.9 8.5 0.0 3.1 3 0 0 3 3 3 1 FR47-like protein IL10 PF00726.17 GBG59354.1 - 0.19 11.2 0.1 0.38 10.2 0.1 1.4 1 0 0 1 1 1 0 Interleukin 10 AP2 PF00847.20 GBG59355.1 - 1.8e-08 34.5 4.1 0.0014 18.8 0.1 3.4 3 0 0 3 3 3 2 AP2 domain FR47 PF08445.10 GBG59355.1 - 0.0097 15.9 0.0 1.9 8.5 0.0 3.1 3 0 0 3 3 3 1 FR47-like protein IL10 PF00726.17 GBG59355.1 - 0.19 11.2 0.1 0.38 10.2 0.1 1.4 1 0 0 1 1 1 0 Interleukin 10 Ras PF00071.22 GBG59356.1 - 9.3e-58 194.4 0.2 1.2e-57 194.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG59356.1 - 1e-36 125.8 0.1 1.4e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG59356.1 - 1e-14 54.3 0.1 1.3e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GBG59356.1 - 3e-06 26.8 0.0 4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GBG59356.1 - 2.3e-05 24.0 0.1 9e-05 22.1 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GBG59356.1 - 6.8e-05 22.3 0.1 8.8e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GBG59356.1 - 0.00017 21.6 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GBG59356.1 - 0.00021 21.4 0.0 0.00035 20.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG59356.1 - 0.0016 18.0 0.1 0.027 14.0 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 GBG59356.1 - 0.031 13.8 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 GBG59356.1 - 0.063 12.7 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein DUF4407 PF14362.6 GBG59357.1 - 0.48 9.7 8.0 0.56 9.5 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 GBG59357.1 - 0.76 10.4 3.5 6 7.6 0.3 2.2 2 0 0 2 2 2 0 Initiation control protein YabA DUF4228 PF14009.6 GBG59357.1 - 1.4 9.3 9.4 2.1 8.7 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) RVT_1 PF00078.27 GBG59358.1 - 4.1e-31 108.2 0.0 6.3e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59358.1 - 9.1e-28 96.2 0.0 1.2e-13 50.9 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59358.1 - 7.2e-18 64.8 0.0 2e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59359.1 - 2.7e-10 40.6 0.1 7.1e-10 39.3 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59359.1 - 2e-08 34.8 0.1 4.6e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG59359.1 - 0.00045 20.0 0.1 0.00077 19.3 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Pep_deformylase PF01327.21 GBG59359.1 - 0.0048 16.5 2.4 0.011 15.3 2.4 1.5 1 0 0 1 1 1 1 Polypeptide deformylase Retrotrans_gag PF03732.17 GBG59359.1 - 0.0088 16.3 0.1 0.046 14.0 0.0 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein RVP PF00077.20 GBG59359.1 - 0.021 15.1 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-FCS PF06467.14 GBG59359.1 - 0.092 12.7 1.4 0.21 11.6 1.4 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CCHC PF00098.23 GBG59359.1 - 0.34 11.1 2.5 0.83 9.8 2.5 1.7 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG59360.1 - 7e-08 32.9 0.0 1.7e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59360.1 - 1.3e-05 25.7 0.1 3.8e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG59360.1 - 0.0027 18.0 0.0 0.007 16.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG59360.1 - 0.022 15.0 0.7 0.056 13.7 0.3 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein BORG_CEP PF14957.6 GBG59360.1 - 3.5 8.8 9.0 5 8.3 0.3 2.6 2 0 0 2 2 2 0 Cdc42 effector TRAP_alpha PF03896.16 GBG59360.1 - 4.7 6.3 8.2 3.1 6.9 0.1 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 GBG59360.1 - 5.8 5.6 10.8 6.7 5.4 0.8 2.1 2 0 0 2 2 2 0 Presenilin TPR_19 PF14559.6 GBG59361.1 - 0.00031 21.2 0.0 0.00054 20.4 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG59361.1 - 0.03 14.4 1.9 3.5 8.0 0.1 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG59361.1 - 0.15 12.0 1.5 1.2 9.1 0.1 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat Integrase_H2C2 PF17921.1 GBG59363.1 - 5e-14 52.2 0.3 1.3e-13 50.9 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG59363.1 - 4.7e-05 23.9 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG59363.1 - 0.0012 19.0 0.0 0.0041 17.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG59363.1 - 0.0019 18.8 0.0 0.0041 17.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG59363.1 - 0.17 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG59363.1 - 1 9.6 4.9 0.18 12.0 0.7 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 eIF-5_eIF-2B PF01873.17 GBG59365.1 - 7.5e-34 116.1 0.1 1.3e-33 115.3 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 CLASP_N PF12348.8 GBG59366.1 - 2.2e-06 27.4 0.2 3.1e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.6 GBG59366.1 - 0.013 15.9 3.1 1.5 9.2 0.1 2.8 2 1 1 3 3 3 0 HEAT repeats Adaptin_N PF01602.20 GBG59366.1 - 0.059 11.9 3.7 0.71 8.3 0.6 2.8 1 1 2 3 3 3 0 Adaptin N terminal region V-ATPase_H_N PF03224.14 GBG59366.1 - 0.059 12.6 0.1 0.08 12.2 0.1 1.1 1 0 0 1 1 1 0 V-ATPase subunit H HEAT PF02985.22 GBG59366.1 - 0.18 12.2 1.6 25 5.5 0.1 3.3 3 0 0 3 3 3 0 HEAT repeat RTP1_C1 PF10363.9 GBG59366.1 - 0.18 12.0 0.2 43 4.3 0.2 2.8 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Myb_DNA-bind_4 PF13837.6 GBG59367.1 - 1.6e-07 31.6 0.6 1e-06 29.0 0.3 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain ABC_trans_aux PF03886.13 GBG59367.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component Myb_DNA-bind_4 PF13837.6 GBG59368.1 - 3.4e-12 46.6 3.0 6.2e-12 45.7 3.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG59368.1 - 0.24 11.5 3.3 0.45 10.6 3.3 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Sin_N PF04801.13 GBG59368.1 - 0.46 9.6 3.7 0.67 9.1 3.7 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region zf-TRAF PF02176.18 GBG59369.1 - 1.9e-11 44.5 14.5 0.00025 21.7 8.8 3.6 2 1 1 3 3 3 3 TRAF-type zinc finger zf-TRAF_2 PF15965.5 GBG59369.1 - 1.1e-06 29.0 21.1 0.00029 21.2 5.5 2.8 2 1 1 3 3 3 2 TRAF-like zinc-finger ubiquitin PF00240.23 GBG59369.1 - 0.00016 21.3 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Sina PF03145.16 GBG59369.1 - 0.0028 17.6 0.6 0.0028 17.6 0.6 3.1 1 1 2 3 3 3 2 Seven in absentia protein family zf_UBZ PF18439.1 GBG59369.1 - 0.0031 17.1 0.1 0.84 9.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger TMF_DNA_bd PF12329.8 GBG59369.1 - 0.051 13.6 0.3 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DM PF00751.18 GBG59369.1 - 1.2 9.1 11.8 1.2 9.1 2.4 3.4 2 1 1 3 3 3 0 DM DNA binding domain Ribosomal_60s PF00428.19 GBG59369.1 - 3.1 8.4 8.2 6 7.5 8.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Folate_rec PF03024.14 GBG59370.1 - 0.00019 21.4 8.8 0.0005 20.0 8.8 1.6 1 1 0 1 1 1 1 Folate receptor family DEAD PF00270.29 GBG59371.1 - 5.7e-11 42.5 0.0 8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG59371.1 - 0.00019 21.7 0.0 0.0007 19.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PAS_11 PF14598.6 GBG59371.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 PAS domain AAA_22 PF13401.6 GBG59371.1 - 0.17 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TRIC PF05197.13 GBG59373.1 - 1.8e-14 53.8 0.6 2.4e-14 53.4 0.6 1.1 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 GBG59373.1 - 5.6e-05 22.9 0.6 0.0041 17.0 0.0 2.5 2 0 0 2 2 2 2 UPF0126 domain TRIC PF05197.13 GBG59374.1 - 1.2e-14 54.4 0.6 1.6e-14 54.0 0.6 1.2 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 GBG59374.1 - 3.3e-05 23.7 0.5 0.003 17.4 0.0 2.5 2 0 0 2 2 2 2 UPF0126 domain TPR_2 PF07719.17 GBG59375.1 - 5.9e-15 54.1 8.1 3.2e-06 26.8 0.7 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GBG59375.1 - 2.5e-12 46.9 3.2 2.6e-06 27.6 1.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG59375.1 - 3.4e-12 45.6 7.7 8.5e-06 25.4 0.6 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG59375.1 - 5e-12 45.0 6.3 9.7e-06 25.4 0.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG59375.1 - 3.1e-09 36.3 10.1 1.1e-08 34.6 1.5 3.9 3 1 2 5 5 5 1 TPR repeat TPR_16 PF13432.6 GBG59375.1 - 2.4e-08 34.5 6.0 6.5e-05 23.5 1.2 3.2 2 1 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG59375.1 - 1.1e-07 31.4 0.6 0.0048 16.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG59375.1 - 1.1e-07 31.8 2.0 6.8e-05 23.0 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG59375.1 - 4.9e-07 30.0 6.8 0.12 13.2 0.1 4.7 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG59375.1 - 3.3e-06 27.5 2.2 1.6e-05 25.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG59375.1 - 2e-05 24.3 4.2 0.12 12.3 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG59375.1 - 0.00053 20.5 7.8 0.71 10.6 0.2 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 GBG59375.1 - 0.0098 15.1 2.3 0.018 14.3 2.3 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat SNAP PF14938.6 GBG59375.1 - 0.036 13.5 2.4 0.082 12.3 2.4 1.5 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.9 GBG59375.1 - 0.083 12.4 0.1 0.26 10.8 0.1 1.9 1 0 0 1 1 1 0 SHNi-TPR kleA_kleC PF17383.2 GBG59375.1 - 0.1 12.9 0.4 6.1 7.3 0.5 2.9 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A ANAPC3 PF12895.7 GBG59375.1 - 0.21 11.9 3.7 0.38 11.0 1.9 2.5 2 1 1 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 IMUP PF15761.5 GBG59375.1 - 0.6 10.8 3.7 0.82 10.4 0.4 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein RVT_1 PF00078.27 GBG59376.1 - 2e-19 70.0 0.0 5.1e-19 68.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG59376.1 - 8.3e-06 25.6 3.2 2.2e-05 24.3 3.2 1.8 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG59376.1 - 0.00074 20.0 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59376.1 - 0.00091 19.8 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59376.1 - 0.0022 17.7 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GBG59376.1 - 0.02 14.7 4.1 0.043 13.6 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 GBG59376.1 - 0.043 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Lin-8 PF03353.15 GBG59376.1 - 1.6 8.2 19.6 3.2 7.2 19.6 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pox_Ag35 PF03286.14 GBG59376.1 - 3.4 7.4 16.4 10 5.8 16.4 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.12 GBG59376.1 - 6.5 6.1 32.4 14 5.0 32.4 1.4 1 0 0 1 1 1 0 SDA1 DUF4683 PF15735.5 GBG59376.1 - 7.7 6.0 9.3 13 5.3 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) RVT_1 PF00078.27 GBG59377.1 - 1e-31 110.2 0.1 1.8e-31 109.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59377.1 - 1.7e-15 56.9 0.2 3.6e-15 55.8 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG59377.1 - 0.00092 19.4 0.2 0.0042 17.3 0.4 2.1 2 0 0 2 2 2 1 H2C2 zinc finger S1-P1_nuclease PF02265.16 GBG59378.1 - 1.2e-07 31.8 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease Glucos_trans_II PF14264.6 GBG59378.1 - 0.007 15.8 0.0 0.0084 15.5 0.0 1.0 1 0 0 1 1 1 1 Glucosyl transferase GtrII S1-P1_nuclease PF02265.16 GBG59379.1 - 1.2e-07 31.8 0.0 1.7e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease Glucos_trans_II PF14264.6 GBG59379.1 - 0.014 14.8 0.0 0.017 14.5 0.0 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII S1-P1_nuclease PF02265.16 GBG59380.1 - 7.3e-23 81.7 0.4 8.6e-23 81.4 0.4 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease FERM_f0 PF16511.5 GBG59382.1 - 0.19 12.1 11.6 11 6.4 0.5 4.2 1 1 4 5 5 5 0 N-terminal or F0 domain of Talin-head FERM PMSR PF01625.21 GBG59382.1 - 0.8 9.9 5.7 1.9 8.6 0.3 2.7 1 1 1 2 2 2 0 Peptide methionine sulfoxide reductase Clathrin_propel PF01394.20 GBG59382.1 - 6.9 7.2 7.7 2.1 8.8 0.9 2.6 3 0 0 3 3 3 0 Clathrin propeller repeat IMUP PF15761.5 GBG59383.1 - 0.012 16.3 2.8 0.13 13.0 0.7 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein Herpes_pp85 PF04637.12 GBG59383.1 - 0.89 7.9 4.6 1.2 7.4 4.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) UbiA PF01040.18 GBG59384.1 - 2.9e-30 105.4 5.0 2.4e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 UbiA prenyltransferase family FAM176 PF14851.6 GBG59384.1 - 6.6e-05 22.6 0.2 0.00011 21.9 0.2 1.3 1 0 0 1 1 1 1 FAM176 family Plasmodium_Vir PF05795.11 GBG59384.1 - 0.00068 19.2 2.7 0.00093 18.7 2.7 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein SpoIIP PF07454.11 GBG59384.1 - 0.0017 17.9 0.2 0.002 17.7 0.2 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 GBG59384.1 - 0.0035 17.1 0.1 0.0051 16.6 0.1 1.2 1 0 0 1 1 1 1 Connexin BSP_II PF05432.11 GBG59384.1 - 0.0056 16.4 17.7 0.0079 15.9 17.7 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Eapp_C PF10238.9 GBG59384.1 - 0.0059 16.7 0.4 0.0078 16.3 0.4 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein BUD22 PF09073.10 GBG59384.1 - 0.0065 15.9 10.7 0.0083 15.5 10.7 1.0 1 0 0 1 1 1 1 BUD22 DUF2828 PF11443.8 GBG59384.1 - 0.0081 14.3 0.4 0.011 13.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF1754 PF08555.10 GBG59384.1 - 0.0083 16.9 20.9 0.012 16.4 20.9 1.1 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) RPA43_OB PF17875.1 GBG59384.1 - 0.011 16.4 0.2 0.015 15.9 0.2 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I OAD_gamma PF04277.13 GBG59384.1 - 0.021 15.4 3.1 0.021 15.4 3.1 2.2 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Presenilin PF01080.17 GBG59384.1 - 0.045 12.5 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Presenilin DUF4337 PF14235.6 GBG59384.1 - 0.068 13.3 0.4 0.068 13.3 0.4 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4337) CENP-B_dimeris PF09026.10 GBG59384.1 - 0.071 13.5 1.0 0.12 12.8 1.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain G0-G1_switch_2 PF15103.6 GBG59384.1 - 0.076 13.4 1.8 0.15 12.5 1.8 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 S1FA PF04689.13 GBG59384.1 - 0.078 13.1 6.8 0.19 11.9 6.8 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA OATP PF03137.20 GBG59384.1 - 0.081 11.2 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family V_ATPase_I PF01496.19 GBG59384.1 - 0.1 10.5 0.6 0.15 10.0 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMC3_TMCO1 PF01956.16 GBG59384.1 - 0.13 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RXT2_N PF08595.11 GBG59384.1 - 0.15 12.0 6.9 0.23 11.5 6.9 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal FancD2 PF14631.6 GBG59384.1 - 0.17 9.3 2.1 0.2 9.0 2.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease AgrB PF04647.15 GBG59384.1 - 0.18 11.1 0.1 0.18 11.1 0.1 1.9 2 0 0 2 2 2 0 Accessory gene regulator B MscS_TM PF12794.7 GBG59384.1 - 0.2 10.5 1.3 0.33 9.8 1.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 AIF_C PF14721.6 GBG59384.1 - 0.21 12.0 1.3 0.33 11.3 1.3 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pox_Ag35 PF03286.14 GBG59384.1 - 0.45 10.3 17.8 0.65 9.7 17.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.12 GBG59384.1 - 0.57 9.5 6.7 0.77 9.1 6.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT LapA_dom PF06305.11 GBG59384.1 - 0.6 10.0 0.1 0.6 10.0 0.1 2.3 2 0 0 2 2 1 0 Lipopolysaccharide assembly protein A domain RR_TM4-6 PF06459.12 GBG59384.1 - 1.4 8.7 10.4 1.9 8.3 10.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AP3D1 PF06375.11 GBG59384.1 - 1.6 9.0 23.2 2.5 8.3 23.2 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Mlh1_C PF16413.5 GBG59384.1 - 1.6 8.1 3.8 2.3 7.5 3.8 1.2 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus ATPase_gene1 PF09527.10 GBG59384.1 - 2.2 8.5 13.5 0.14 12.4 3.8 2.8 3 0 0 3 3 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Rtf2 PF04641.12 GBG59384.1 - 3.2 7.0 14.3 4.5 6.6 14.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger ORC_WH_C PF18137.1 GBG59384.1 - 4.6 7.3 8.9 7.1 6.7 8.9 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal RPN2_C PF18004.1 GBG59384.1 - 4.6 7.1 18.3 7 6.6 18.3 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Afi1 PF07792.12 GBG59384.1 - 5.3 7.5 8.7 9.4 6.7 8.7 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking eIF3_subunit PF08597.10 GBG59384.1 - 5.5 6.8 22.6 7.8 6.3 22.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SR-25 PF10500.9 GBG59384.1 - 7 6.2 19.2 9.9 5.7 19.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1387 PF07139.11 GBG59384.1 - 8.3 6.0 18.6 12 5.6 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PPL5 PF18168.1 GBG59384.1 - 9.1 5.5 7.3 13 5.0 7.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Radial_spoke PF04712.12 GBG59384.1 - 9.3 5.1 11.7 12 4.6 11.7 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein ABC2_membrane PF01061.24 GBG59386.1 - 8.9e-31 107.0 18.3 1.7e-30 106.1 18.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GBG59386.1 - 3.7e-25 89.0 0.0 6.3e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG59386.1 - 8.1e-09 35.7 2.1 0.00035 20.5 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GBG59386.1 - 4.2e-06 27.3 0.2 1e-05 26.0 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GBG59386.1 - 9.4e-05 22.1 0.1 0.00024 20.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 GBG59386.1 - 0.00037 19.7 14.9 0.00037 19.7 14.9 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GBG59386.1 - 0.00078 19.4 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GBG59386.1 - 0.0025 18.1 0.0 0.046 14.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 GBG59386.1 - 0.0049 16.3 0.1 0.022 14.2 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GBG59386.1 - 0.021 15.3 0.1 0.021 15.3 0.1 2.9 1 1 2 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 GBG59386.1 - 0.03 14.4 0.1 0.06 13.4 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 GBG59386.1 - 0.041 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GBG59386.1 - 0.07 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GBG59386.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Rubis-subs-bind PF09273.11 GBG59387.1 - 7.9e-06 26.6 0.0 0.00015 22.4 0.0 2.4 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 GBG59387.1 - 3.4e-05 24.3 0.2 0.00024 21.5 0.0 2.5 2 1 0 2 2 2 1 SET domain CALCOCO1 PF07888.11 GBG59388.1 - 0.0028 16.6 21.0 0.0028 16.6 21.0 1.8 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like BRE1 PF08647.11 GBG59388.1 - 0.82 9.8 26.0 0.059 13.4 1.5 4.1 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 GBG59388.1 - 1.1 9.3 32.3 7.9 6.5 18.0 4.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC-167 PF15188.6 GBG59388.1 - 3.1 8.2 14.8 0.082 13.3 2.5 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 APG6_N PF17675.1 GBG59388.1 - 7.2 7.2 37.8 0.12 12.8 17.6 3.7 3 1 1 4 4 4 0 Apg6 coiled-coil region RT_RNaseH_2 PF17919.1 GBG59389.1 - 2.2e-33 114.3 0.0 3.8e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59389.1 - 3.3e-31 107.7 0.0 7.3e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59389.1 - 7e-08 32.3 0.1 1.2e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG59390.1 - 0.0055 17.0 0.3 2.2 8.6 0.1 2.5 2 0 0 2 2 2 2 Retrotransposon gag protein WD40 PF00400.32 GBG59391.1 - 1.9e-22 79.1 16.0 2e-05 25.2 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG59391.1 - 0.00022 21.5 0.2 1.6 9.1 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Exo_endo_phos_2 PF14529.6 GBG59392.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase FHA PF00498.26 GBG59393.1 - 5.3e-18 65.1 0.0 9.9e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GBG59393.1 - 0.015 15.6 0.0 0.092 13.1 0.0 2.1 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain SelP_N PF04592.14 GBG59393.1 - 3.9 6.8 14.1 7.2 5.9 14.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region GATase_2 PF00310.21 GBG59394.1 - 9.4e-173 574.7 0.0 1.2e-172 574.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GBG59394.1 - 2.8e-158 526.9 0.9 5.2e-157 522.7 0.1 2.9 3 0 0 3 3 3 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GBG59394.1 - 3.2e-106 354.9 0.0 6.5e-106 353.9 0.0 1.5 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GBG59394.1 - 6.4e-60 202.0 8.5 6.4e-60 202.0 8.5 1.7 2 0 0 2 2 2 1 GXGXG motif FMN_dh PF01070.18 GBG59394.1 - 0.44 9.5 12.8 0.11 11.5 5.6 2.6 3 0 0 3 3 3 0 FMN-dependent dehydrogenase KAAG1 PF15354.6 GBG59394.1 - 2.6 8.7 4.3 1.1 9.8 0.6 2.4 2 0 0 2 2 2 0 Kidney-associated antigen 1 RT_RNaseH PF17917.1 GBG59396.1 - 3e-23 82.1 0.0 6e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59396.1 - 1.5e-21 76.3 0.0 3e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59396.1 - 7.1e-14 51.7 0.4 1.7e-13 50.4 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG59396.1 - 2e-05 25.1 0.1 6.2e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG59396.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59396.1 - 0.023 15.3 0.0 0.058 14.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG59396.1 - 0.15 11.9 1.1 0.27 11.0 1.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Nucleo_P87 PF07267.11 GBG59396.1 - 2.6 6.8 7.8 4.8 5.9 7.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Enolase_C PF00113.22 GBG59397.1 - 5.9e-142 472.2 0.0 8.6e-142 471.7 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GBG59397.1 - 2e-58 196.2 0.2 3.6e-58 195.4 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GBG59397.1 - 5.1e-09 36.0 0.0 8.8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GBG59397.1 - 0.00027 20.2 0.1 0.00064 19.0 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.16 GBG59397.1 - 0.055 13.7 1.0 0.098 12.9 0.2 1.8 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SpoIID PF08486.10 GBG59397.1 - 0.17 12.5 1.3 0.55 10.8 0.1 2.5 3 1 0 3 3 3 0 Stage II sporulation protein LRR_6 PF13516.6 GBG59399.1 - 5.2e-10 38.6 1.4 1.9e-05 24.3 0.2 3.7 3 0 0 3 3 3 2 Leucine Rich repeat SAPS PF04499.15 GBG59399.1 - 0.042 12.6 1.6 0.73 8.6 0.0 2.8 2 1 1 3 3 3 0 SIT4 phosphatase-associated protein LRR_4 PF12799.7 GBG59399.1 - 0.048 14.1 0.2 19 5.8 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG59399.1 - 0.049 13.4 0.3 1.3 8.8 0.2 2.4 1 1 1 2 2 2 0 Leucine rich repeat RRM_1 PF00076.22 GBG59400.1 - 8e-17 60.8 0.0 1.3e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GBG59400.1 - 2.4e-07 30.5 1.9 3.7e-07 29.9 1.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG59400.1 - 0.13 12.2 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RRM_7 PF16367.5 GBG59400.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif PPR_2 PF13041.6 GBG59402.1 - 1.9e-66 220.1 7.1 1.8e-13 50.4 0.4 10.9 5 3 6 11 11 11 11 PPR repeat family PPR PF01535.20 GBG59402.1 - 3.9e-63 205.4 17.3 1.6e-08 34.2 0.1 10.8 11 0 0 11 11 11 9 PPR repeat PPR_1 PF12854.7 GBG59402.1 - 9e-60 198.1 0.7 9.8e-07 28.4 0.0 11.0 11 0 0 11 11 11 8 PPR repeat PPR_3 PF13812.6 GBG59402.1 - 2e-51 171.9 0.0 1.1e-14 54.2 0.1 7.5 5 3 5 10 10 10 10 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG59402.1 - 4.7e-24 84.9 0.1 1.3e-10 41.0 0.0 4.4 4 0 0 4 4 4 4 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 GBG59402.1 - 0.015 14.4 0.1 0.21 10.7 0.0 2.8 2 1 1 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_16 PF13432.6 GBG59402.1 - 0.29 11.8 5.6 2.1 9.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Integrase_H2C2 PF17921.1 GBG59403.1 - 8.1e-15 54.7 0.1 1.9e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG59403.1 - 7.4e-11 42.3 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG59403.1 - 2.2e-06 27.3 0.0 3.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG59403.1 - 1.4e-05 25.2 0.0 3.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger CAP PF00188.26 GBG59404.1 - 0.18 12.6 2.3 0.59 11.0 2.3 1.9 1 1 0 1 1 1 0 Cysteine-rich secretory protein family Tad PF13400.6 GBG59404.1 - 2.7 8.4 8.3 0.83 10.0 0.9 2.4 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Dimer_Tnp_hAT PF05699.14 GBG59406.1 - 5.6e-07 29.3 0.1 4.7e-06 26.3 0.0 2.5 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region GBV-C_env PF12786.7 GBG59407.1 - 0.034 12.8 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 GB virus C genotype envelope CAP PF00188.26 GBG59407.1 - 0.13 13.1 0.2 0.23 12.3 0.2 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family RVT_1 PF00078.27 GBG59410.1 - 3.6e-25 88.8 0.0 5.4e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP PF00188.26 GBG59411.1 - 7.9e-05 23.5 0.8 0.00014 22.7 0.8 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family INCENP_ARK-bind PF03941.15 GBG59411.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region PGA_cap PF09587.10 GBG59412.1 - 3 7.2 6.6 1.6 8.1 4.5 1.5 1 1 1 2 2 2 0 Bacterial capsule synthesis protein PGA_cap RVT_1 PF00078.27 GBG59413.1 - 9.7e-29 100.5 0.0 1.5e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_jaz PF12171.8 GBG59414.1 - 9.8e-06 25.7 0.5 1.8e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GBG59414.1 - 3.2e-05 24.2 0.5 3.2e-05 24.2 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 GBG59414.1 - 0.0076 16.3 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Pkinase_Tyr PF07714.17 GBG59415.1 - 8.3e-20 71.1 0.0 1.9e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG59415.1 - 3.6e-18 65.9 1.3 1.3e-17 64.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain zf-CCHC PF00098.23 GBG59415.1 - 0.00076 19.4 2.8 0.0025 17.8 2.8 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG59415.1 - 0.05 13.3 1.1 0.15 11.8 1.1 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Pkinase PF00069.25 GBG59417.1 - 1.7e-11 44.0 0.1 1.2e-09 37.9 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG59417.1 - 5.6e-11 42.2 0.1 4.8e-08 32.6 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GBG59417.1 - 0.25 11.2 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 GBG59418.1 - 5.9e-13 48.7 0.0 1.6e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59418.1 - 8.2e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG59418.1 - 1e-06 29.2 0.0 2.8e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59418.1 - 2e-06 28.4 0.0 5.4e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59418.1 - 1.8e-05 24.5 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59418.1 - 5.9e-05 22.9 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG59418.1 - 0.00057 20.1 0.0 0.0018 18.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59418.1 - 0.0058 16.9 2.6 0.018 15.3 0.1 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein Use1 PF09753.9 GBG59418.1 - 8.7 6.0 16.4 3.6 7.2 8.5 2.9 3 0 0 3 3 3 0 Membrane fusion protein Use1 zf-DNL PF05180.12 GBG59419.1 - 2.1e-25 88.4 0.0 4.5e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 DNL zinc finger RCC1 PF00415.18 GBG59420.1 - 1.3e-78 259.4 33.9 6.4e-15 55.5 0.2 8.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG59420.1 - 7.2e-29 99.0 47.4 1.7e-08 34.0 2.8 9.2 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat BRX PF08381.11 GBG59420.1 - 1.5e-27 94.7 0.8 2.9e-27 93.8 0.8 1.5 1 0 0 1 1 1 1 Transcription factor regulating root and shoot growth via Pin3 FYVE PF01363.21 GBG59420.1 - 1.1e-14 54.3 13.3 2e-14 53.5 13.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH_12 PF16457.5 GBG59420.1 - 4.7e-09 36.9 0.0 1.1e-08 35.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 GBG59420.1 - 0.0083 16.2 0.0 0.022 14.9 0.0 1.7 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology FYVE_2 PF02318.16 GBG59420.1 - 0.06 13.6 8.3 0.12 12.5 8.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Mcl1_mid PF12341.8 GBG59420.1 - 0.14 11.5 0.2 3.5 6.9 0.3 2.7 2 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region zf-ribbon_3 PF13248.6 GBG59420.1 - 3.4 7.2 6.9 0.55 9.7 0.9 2.9 2 0 0 2 2 2 0 zinc-ribbon domain RCC1 PF00415.18 GBG59421.1 - 1e-78 259.7 33.9 6.2e-15 55.5 0.2 8.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG59421.1 - 5.8e-29 99.3 47.5 1.7e-08 34.0 2.8 9.2 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat BRX PF08381.11 GBG59421.1 - 1.5e-27 94.7 0.8 2.8e-27 93.8 0.8 1.5 1 0 0 1 1 1 1 Transcription factor regulating root and shoot growth via Pin3 FYVE PF01363.21 GBG59421.1 - 1.1e-14 54.4 13.3 1.9e-14 53.5 13.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH_12 PF16457.5 GBG59421.1 - 4.5e-09 36.9 0.0 1.1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 GBG59421.1 - 0.008 16.3 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology FYVE_2 PF02318.16 GBG59421.1 - 0.058 13.6 8.3 0.12 12.6 8.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Mcl1_mid PF12341.8 GBG59421.1 - 0.13 11.6 0.2 4.3 6.6 0.2 2.8 2 1 1 3 3 3 0 Minichromosome loss protein, Mcl1, middle region zf-ribbon_3 PF13248.6 GBG59421.1 - 3.2 7.3 6.9 0.53 9.8 0.9 2.9 2 0 0 2 2 2 0 zinc-ribbon domain TPR_4 PF07721.14 GBG59422.1 - 0.042 14.5 1.8 39 5.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3537 PF12056.8 GBG59422.1 - 0.15 10.9 1.3 0.19 10.5 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3537) Secretin_N_2 PF07655.13 GBG59422.1 - 2 9.0 51.8 0.3 11.7 13.1 3.5 2 1 1 3 3 3 0 Secretin N-terminal domain Apis_Csd PF11671.8 GBG59422.1 - 8 6.5 37.2 1.5 8.8 6.5 3.2 3 0 0 3 3 3 0 Complementary sex determiner protein CDC45 PF02724.14 GBG59423.1 - 0.0011 17.4 9.3 0.0014 17.1 9.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop53 PF07767.11 GBG59423.1 - 0.56 9.5 16.7 0.74 9.1 16.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RRN3 PF05327.11 GBG59423.1 - 1.2 7.5 6.1 1.6 7.1 6.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 GBG59423.1 - 5.7 6.0 6.0 8.1 5.5 6.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 GBG59423.1 - 5.8 5.0 14.7 7 4.7 14.7 1.1 1 0 0 1 1 1 0 Nop14-like family PUF PF00806.19 GBG59424.1 - 1.3e-67 219.8 11.1 3.8e-09 35.7 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat NABP PF07990.12 GBG59424.1 - 4.6e-09 36.3 57.6 0.0022 17.6 4.2 4.7 3 1 1 4 4 4 3 Nucleic acid binding protein NABP Macoilin PF09726.9 GBG59424.1 - 0.52 8.8 29.7 0.99 7.9 29.7 1.4 1 0 0 1 1 1 0 Macoilin family Folate_carrier PF01770.18 GBG59424.1 - 0.77 8.4 9.9 1.6 7.4 9.9 1.6 1 0 0 1 1 1 0 Reduced folate carrier CDC45 PF02724.14 GBG59424.1 - 1.5 7.0 25.0 2.4 6.3 25.0 1.2 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 GBG59424.1 - 2 5.4 31.3 3.1 4.8 31.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LMBR1 PF04791.16 GBG59424.1 - 3 6.6 10.6 4.7 6.0 10.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.9 GBG59424.1 - 9.5 4.3 56.0 29 2.7 55.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.32 GBG59426.1 - 3e-18 65.8 15.7 4.1e-05 24.3 0.2 10.5 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG59426.1 - 4.2e-12 46.2 0.1 0.26 11.6 0.0 6.4 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 GBG59426.1 - 8.1e-05 22.2 0.5 0.00014 21.4 0.5 1.4 1 0 0 1 1 1 1 LisH-like dimerisation domain Frtz PF11768.8 GBG59426.1 - 0.007 14.7 0.0 0.46 8.7 0.0 2.8 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz MutS_I PF01624.20 GBG59427.1 - 3.4e-28 98.2 0.0 5.1e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 GBG59427.1 - 2.7e-05 24.4 0.1 5.3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain II DUF659 PF04937.15 GBG59428.1 - 7.9e-17 61.5 0.0 1.8e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59428.1 - 0.013 15.3 0.2 0.14 12.0 0.2 2.3 1 1 0 1 1 1 0 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG59429.1 - 9.9e-58 195.3 4.2 4.8e-29 101.5 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59429.1 - 3.8e-38 130.0 0.0 3.7e-22 78.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59429.1 - 1.6e-32 111.5 0.0 5.4e-23 80.9 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59429.1 - 2.9e-15 56.1 1.8 3.8e-15 55.7 0.5 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG59429.1 - 2.3e-06 28.2 0.0 7.2e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59429.1 - 1.8e-05 25.2 0.0 4.8e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59429.1 - 0.00013 21.8 0.0 0.00033 20.4 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59429.1 - 0.0029 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG59429.1 - 0.086 13.1 0.2 0.24 11.6 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger DUF659 PF04937.15 GBG59431.1 - 1.5e-12 47.6 0.0 2.6e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59431.1 - 4.1e-08 32.9 0.5 8.7e-08 31.9 0.5 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UCMA PF17085.5 GBG59431.1 - 0.29 11.1 5.3 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Unique cartilage matrix associated protein Asp_protease_2 PF13650.6 GBG59432.1 - 0.00013 22.6 0.0 0.00024 21.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59432.1 - 0.00037 21.0 0.0 0.00071 20.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG59432.1 - 0.0009 19.5 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG59432.1 - 0.0045 16.8 0.1 0.014 15.2 0.1 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59432.1 - 0.0087 15.8 0.0 0.018 14.8 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease MutS_V PF00488.21 GBG59433.1 - 9.2e-69 231.3 2.1 2.9e-67 226.3 1.3 3.0 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 GBG59433.1 - 2.8e-33 115.7 0.0 9.4e-33 114.0 0.0 2.0 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 GBG59433.1 - 1.7e-05 25.1 0.0 6.4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 MutS family domain IV RsmJ PF04378.13 GBG59433.1 - 0.12 11.5 0.0 17 4.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomal RNA large subunit methyltransferase D, RlmJ eIF3_subunit PF08597.10 GBG59434.1 - 0.54 10.1 13.5 0.065 13.1 8.9 1.7 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Sel1 PF08238.12 GBG59435.1 - 2e-73 241.2 43.1 3.6e-09 37.0 0.6 10.4 11 0 0 11 11 11 9 Sel1 repeat TPR_6 PF13174.6 GBG59435.1 - 0.0063 17.1 15.3 0.015 15.9 0.2 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG59435.1 - 0.62 10.0 10.0 19 5.3 0.4 6.6 7 1 0 7 7 7 0 Tetratricopeptide repeat DUF659 PF04937.15 GBG59436.1 - 1.5e-41 141.8 0.1 6.6e-22 78.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) zf-CCHC_6 PF15288.6 GBG59438.1 - 0.059 13.2 1.0 0.2 11.5 1.0 1.9 1 0 0 1 1 1 0 Zinc knuckle O-FucT PF10250.9 GBG59439.1 - 3.6e-14 53.2 0.0 3.8e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase UCH PF00443.29 GBG59440.1 - 1.4e-39 136.2 0.0 6e-39 134.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GBG59440.1 - 3.2e-11 43.4 0.1 3.2e-11 43.4 0.1 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GBG59440.1 - 3.5e-10 40.0 0.0 0.0084 15.7 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase SpoIIP PF07454.11 GBG59440.1 - 4.1 6.8 9.1 1.9 7.9 3.9 2.5 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) U79_P34 PF03064.16 GBG59441.1 - 1.6 8.0 41.2 1.9 7.8 41.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FAM60A PF15396.6 GBG59441.1 - 1.7 8.6 24.3 1.8 8.5 24.3 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF3807 PF12720.7 GBG59441.1 - 5.3 7.3 36.2 6.2 7.1 36.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 GBG59441.1 - 6.4 5.4 25.9 6.9 5.3 25.9 1.0 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 GBG59441.1 - 7.5 6.6 16.9 10 6.2 16.9 1.3 1 0 0 1 1 1 0 DDHD domain FGF-BP1 PF06473.12 GBG59441.1 - 8.1 6.2 28.7 9.4 6.0 28.7 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) NPR3 PF03666.13 GBG59441.1 - 8.5 5.0 31.9 10 4.8 31.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MAT1 PF06391.13 GBG59442.1 - 0.62 9.9 15.8 1.2 9.0 15.8 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 YtxH PF12732.7 GBG59442.1 - 3 8.4 8.1 10 6.8 0.0 2.8 1 1 1 2 2 2 0 YtxH-like protein Ribosomal_L7Ae PF01248.26 GBG59443.1 - 3.3e-26 90.9 0.6 4.4e-26 90.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 GBG59443.1 - 0.0011 19.1 0.0 0.0012 18.9 0.0 1.2 1 1 0 1 1 1 1 RNase P subunit Pop3 FlpD PF02662.16 GBG59443.1 - 0.21 11.6 1.5 1.5 8.8 0.1 2.3 2 1 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit CAP_N PF01213.19 GBG59444.1 - 2.4 7.6 11.6 0.054 13.0 4.5 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal zf-CCHC PF00098.23 GBG59445.1 - 1.4e-05 24.9 1.2 2.8e-05 24.0 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG59445.1 - 0.014 15.4 0.7 0.014 15.4 0.7 2.3 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG59445.1 - 0.035 13.9 0.4 0.064 13.1 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle CnrY PF17524.2 GBG59445.1 - 0.26 11.5 0.8 0.6 10.4 0.8 1.5 1 0 0 1 1 1 0 Anti-sigma factor CnrY Curto_V2 PF07325.11 GBG59445.1 - 0.41 10.5 6.2 0.27 11.1 4.3 1.6 1 1 0 1 1 1 0 Curtovirus V2 protein Sec10 PF07393.11 GBG59446.1 - 4.1e-123 412.3 0.0 4.3e-59 200.7 0.0 3.2 2 1 0 3 3 3 3 Exocyst complex component Sec10 COG7 PF10191.9 GBG59446.1 - 5e-05 21.8 0.0 0.00017 20.0 0.0 1.7 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) COG4 PF08318.12 GBG59446.1 - 0.0027 16.9 0.0 0.017 14.2 0.1 2.0 2 0 0 2 2 2 1 COG4 transport protein DUF1712 PF08217.11 GBG59446.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Thioredoxin PF00085.20 GBG59447.1 - 3e-06 27.2 0.1 5.1e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 GBG59447.1 - 0.0026 17.9 0.2 0.0063 16.7 0.2 1.6 1 0 0 1 1 1 1 Thioredoxin-like RTT107_BRCT_6 PF16771.5 GBG59447.1 - 0.1 12.8 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain RVT_1 PF00078.27 GBG59448.1 - 4.1e-23 82.1 0.9 3.6e-22 79.0 0.9 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG59448.1 - 1.1e-05 26.0 0.0 2.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59448.1 - 5.6e-05 23.6 0.0 0.00022 21.7 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59448.1 - 0.0002 21.1 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59448.1 - 0.0084 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CLZ PF16526.5 GBG59448.1 - 0.18 12.2 2.7 1.6 9.2 0.5 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 GBG59448.1 - 0.51 9.6 12.6 1.2 8.4 6.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PIEZO PF15917.5 GBG59448.1 - 1.1 8.7 4.9 2.9 7.3 4.9 1.6 1 0 0 1 1 1 0 Piezo Gal_Lectin PF02140.18 GBG59448.1 - 1.4 9.4 5.3 3.7 8.0 5.3 1.7 1 0 0 1 1 1 0 Galactose binding lectin domain Ribosomal_L32e PF01655.18 GBG59449.1 - 3.6e-27 94.9 0.1 5.4e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L32 Thioredoxin PF00085.20 GBG59449.1 - 2.5e-05 24.2 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin QueC PF06508.13 GBG59449.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Complex1_LYR PF05347.15 GBG59450.1 - 3.9e-16 58.8 0.5 5.2e-16 58.5 0.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GBG59450.1 - 0.00033 21.3 0.3 0.00065 20.4 0.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 GBG59450.1 - 0.011 16.3 0.3 0.015 15.9 0.3 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Integrase_H2C2 PF17921.1 GBG59451.1 - 4.8e-14 52.2 0.3 9.8e-14 51.2 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59451.1 - 9.1e-05 22.6 0.0 0.00053 20.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG59451.1 - 0.00051 20.6 0.0 0.0022 18.6 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59451.1 - 0.11 13.1 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG59451.1 - 2.5 8.3 7.7 0.29 11.3 2.6 2.1 2 0 0 2 2 2 0 Zinc knuckle Sec6 PF06046.13 GBG59451.1 - 3.6 5.8 8.2 6.9 4.9 8.2 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec6 ARGLU PF15346.6 GBG59452.1 - 3.3e-37 127.7 56.2 3.3e-37 127.7 56.2 2.2 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 DUF445 PF04286.12 GBG59452.1 - 0.75 9.5 22.5 0.89 9.3 22.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) WD40 PF00400.32 GBG59453.1 - 0.048 14.5 5.5 9.3 7.3 0.0 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat NOA36 PF06524.12 GBG59453.1 - 0.096 12.0 12.0 0.034 13.5 1.4 2.2 2 0 0 2 2 2 0 NOA36 protein Radial_spoke PF04712.12 GBG59453.1 - 3.7 6.4 8.7 0.32 9.9 0.3 2.4 2 0 0 2 2 2 0 Radial spokehead-like protein PAXIP1_C PF15364.6 GBG59453.1 - 7.3 6.9 10.0 2.7 8.3 0.6 2.4 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein WD40 PF00400.32 GBG59455.1 - 1.3e-08 35.4 1.4 0.00034 21.4 0.6 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG59455.1 - 4e-08 33.4 0.0 1.7 9.0 0.0 5.4 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 GBG59455.1 - 0.034 14.1 0.0 0.087 12.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) AAA PF00004.29 GBG59456.1 - 2.3e-38 131.6 0.0 8.5e-38 129.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG59456.1 - 9e-14 51.0 0.2 2.3e-12 46.5 0.4 2.9 2 1 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 GBG59456.1 - 2e-09 37.3 0.0 4.6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 GBG59456.1 - 7.6e-05 22.9 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GBG59456.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GBG59456.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GBG59456.1 - 0.0023 18.5 0.1 0.0081 16.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GBG59456.1 - 0.0027 17.7 0.0 0.01 15.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GBG59456.1 - 0.0034 17.7 0.1 0.088 13.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GBG59456.1 - 0.007 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GBG59456.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 GBG59456.1 - 0.017 14.4 0.0 0.039 13.2 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_16 PF13191.6 GBG59456.1 - 0.027 14.9 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 GBG59456.1 - 0.029 13.9 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GBG59456.1 - 0.046 14.1 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 GBG59456.1 - 0.047 13.1 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 GBG59456.1 - 0.053 13.5 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GBG59456.1 - 0.07 12.8 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GBG59456.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GBG59456.1 - 0.21 10.9 0.0 1.9 7.8 0.1 2.0 1 1 1 2 2 2 0 KaiC APG17 PF04108.12 GBG59457.1 - 1.7e-06 27.4 23.5 0.0014 17.8 6.0 3.7 2 1 0 3 3 3 2 Autophagy protein Apg17 ATG11 PF10377.9 GBG59457.1 - 2.4e-05 24.4 0.0 0.00011 22.3 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein 11 IKKbetaNEMObind PF12179.8 GBG59457.1 - 0.02 14.9 0.8 0.077 13.0 0.8 2.1 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DUF1319 PF07028.11 GBG59457.1 - 0.024 14.8 1.9 0.6 10.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) BRX_N PF13713.6 GBG59457.1 - 0.26 11.1 1.4 0.77 9.6 1.4 1.8 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain ATG16 PF08614.11 GBG59457.1 - 0.72 10.1 27.0 0.14 12.4 6.3 4.5 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 GBG59457.1 - 3 8.4 12.5 38 4.9 0.0 4.7 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein AP_endonuc_2_N PF07582.12 GBG59458.1 - 0.031 14.0 1.1 0.06 13.1 1.1 1.5 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus RRM_1 PF00076.22 GBG59459.1 - 5.3e-59 196.0 0.7 9.2e-20 70.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GBG59459.1 - 8.7e-10 38.3 0.0 0.039 13.6 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 GBG59459.1 - 9.5e-10 38.4 3.8 1.8e-09 37.5 3.8 1.4 1 0 0 1 1 1 1 WW domain RRM_7 PF16367.5 GBG59459.1 - 8.2e-09 35.5 0.1 0.051 13.7 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif RRM_occluded PF16842.5 GBG59459.1 - 0.00039 20.2 0.0 0.35 10.7 0.0 3.2 3 1 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 GBG59459.1 - 0.0018 18.3 0.4 1.9 8.6 0.0 3.0 3 0 0 3 3 3 2 Limkain b1 RRM_1 PF00076.22 GBG59460.1 - 4.8e-59 196.1 0.7 8.9e-20 70.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GBG59460.1 - 8.5e-10 38.3 0.0 0.037 13.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 GBG59460.1 - 9.3e-10 38.4 3.8 1.7e-09 37.6 3.8 1.4 1 0 0 1 1 1 1 WW domain RRM_7 PF16367.5 GBG59460.1 - 8e-09 35.5 0.1 0.049 13.7 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif RRM_occluded PF16842.5 GBG59460.1 - 0.00036 20.4 0.0 0.34 10.8 0.0 3.2 3 1 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 GBG59460.1 - 0.0016 18.4 0.4 1.8 8.7 0.0 3.0 3 0 0 3 3 3 2 Limkain b1 JAB PF01398.21 GBG59461.1 - 4.2e-25 88.0 0.0 7.2e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GBG59461.1 - 3.6e-23 82.1 0.1 5.6e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Ribosomal_S5_C PF03719.15 GBG59462.1 - 0.12 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Ribosomal_S6 PF01250.17 GBG59463.1 - 8.1e-23 80.5 0.4 1.8e-22 79.4 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S6 GP38 PF05268.11 GBG59463.1 - 0.061 13.0 4.5 0.099 12.3 4.5 1.3 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 SDA1 PF05285.12 GBG59463.1 - 5.7 6.3 12.3 7.4 5.9 12.3 1.2 1 0 0 1 1 1 0 SDA1 DUF4604 PF15377.6 GBG59463.1 - 5.7 7.3 10.1 9.3 6.6 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Fasciclin PF02469.22 GBG59465.1 - 5e-14 52.6 0.0 6.8e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF4370 PF14290.6 GBG59466.1 - 9.6e-44 150.0 0.0 1.2e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4370) DHHC PF01529.20 GBG59467.1 - 5.6e-33 113.9 2.9 5.6e-33 113.9 2.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Caps_synth_CapC PF14102.6 GBG59467.1 - 0.1 13.0 3.2 0.2 12.1 3.2 1.4 1 0 0 1 1 1 0 Capsule biosynthesis CapC EST1_DNA_bind PF10373.9 GBG59469.1 - 5.7e-54 183.5 0.0 9.5e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 GBG59469.1 - 1.7e-19 70.8 0.0 6.5e-19 68.9 0.0 2.1 1 0 0 1 1 1 1 Telomerase activating protein Est1 Med15 PF09606.10 GBG59470.1 - 0.31 9.7 6.8 0.34 9.5 6.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF659 PF04937.15 GBG59471.1 - 9.8e-18 64.5 0.0 1.6e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59471.1 - 0.00029 20.6 0.1 0.00055 19.7 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG59472.1 - 5.4e-18 65.3 0.0 9.6e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59472.1 - 4e-16 58.9 0.3 1.2e-15 57.3 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG59472.1 - 8.9e-16 57.8 0.0 2.5e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG59472.1 - 3.8e-11 42.7 0.1 9.7e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG59472.1 - 4.8e-11 42.9 0.3 4.2e-10 39.9 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG59472.1 - 8.3e-05 22.8 0.1 0.00031 21.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG59472.1 - 0.00022 21.4 0.1 0.00048 20.3 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG59473.1 - 6.7e-23 81.4 0.1 1e-22 80.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG59473.1 - 0.015 15.0 0.0 0.062 13.1 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease EF-hand_1 PF00036.32 GBG59474.1 - 2.7e-35 117.3 18.7 1.2e-09 37.0 1.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GBG59474.1 - 8.4e-32 109.4 11.1 1.6e-16 60.5 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG59474.1 - 4.6e-28 94.7 10.3 1.3e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GBG59474.1 - 2.1e-26 91.5 18.9 6.5e-13 48.3 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GBG59474.1 - 6.6e-21 72.8 15.9 4.8e-06 25.8 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GBG59474.1 - 2.2e-15 56.7 0.5 8.1e-07 29.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GBG59474.1 - 1.6e-07 31.2 7.7 0.11 12.4 0.3 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GBG59474.1 - 6.2e-05 23.3 0.3 0.37 11.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 GBG59474.1 - 0.00041 20.6 1.3 0.18 12.2 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain SurA_N_3 PF13624.6 GBG59474.1 - 0.00042 20.2 1.4 0.37 10.6 0.1 2.1 1 1 1 2 2 2 2 SurA N-terminal domain Dockerin_1 PF00404.18 GBG59474.1 - 0.0011 19.1 0.2 1 9.6 0.0 2.4 2 0 0 2 2 2 2 Dockerin type I domain SUB1_ProdP9 PF18213.1 GBG59474.1 - 0.0063 16.3 2.1 0.0087 15.9 0.3 2.0 1 1 1 2 2 2 1 SUB1 protease Prodomain ProdP9 SurA_N_2 PF13623.6 GBG59474.1 - 0.0075 16.1 2.8 1.3 8.8 0.5 2.8 1 1 1 2 2 2 2 SurA N-terminal domain Sigma54_CBD PF04963.13 GBG59474.1 - 0.011 15.6 0.2 0.015 15.2 0.2 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain HTH_32 PF13565.6 GBG59474.1 - 0.011 16.3 0.0 5.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain UPF0154 PF03672.13 GBG59474.1 - 0.02 14.9 0.9 3.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 GBG59474.1 - 0.03 14.3 1.3 8 6.3 0.0 3.5 1 1 3 4 4 4 0 Caleosin related protein DUF853 PF05872.12 GBG59474.1 - 0.032 12.8 0.2 0.89 8.1 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF3008 PF11450.8 GBG59474.1 - 0.085 13.0 0.2 0.085 13.0 0.2 2.4 3 0 0 3 3 3 0 Protein of unknwon function (DUF3008) MgtE_N PF03448.17 GBG59474.1 - 0.33 11.6 3.0 0.26 11.9 0.5 2.1 3 0 0 3 3 2 0 MgtE intracellular N domain Styelin PF17562.2 GBG59474.1 - 3.3 8.1 8.3 0.59 10.5 1.8 2.8 2 2 1 3 3 3 0 Styelin E1-E2_ATPase PF00122.20 GBG59475.1 - 4.3e-50 169.7 0.1 8.3e-50 168.8 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase RVT_1 PF00078.27 GBG59475.1 - 2.7e-28 99.0 0.1 4.3e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HMA PF00403.26 GBG59475.1 - 1.2e-22 80.1 0.3 3.7e-11 43.3 0.0 3.7 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase PF00702.26 GBG59475.1 - 5e-20 72.7 0.2 1.3e-11 45.2 0.1 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Tox-PL-2 PF15643.6 GBG59475.1 - 0.15 12.2 0.1 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 Papain fold toxin 2 E7 PF00527.18 GBG59475.1 - 1.9 8.7 9.0 4.8 7.5 1.0 3.3 3 0 0 3 3 3 0 E7 protein, Early protein zf-CCHC PF00098.23 GBG59476.1 - 9.2e-05 22.4 4.3 0.00016 21.6 4.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG59476.1 - 9.5e-05 22.3 0.9 0.00026 20.9 0.9 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG59476.1 - 0.018 14.7 1.1 0.036 13.8 1.1 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger FapA PF03961.13 GBG59476.1 - 0.11 11.1 7.1 0.18 10.4 7.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Peptidase_M16 PF00675.20 GBG59476.1 - 0.21 11.5 3.9 0.44 10.5 3.9 1.5 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) Usp PF00582.26 GBG59476.1 - 0.36 11.3 4.8 5.8 7.4 0.0 2.6 2 1 0 2 2 2 0 Universal stress protein family zf-CCHC_2 PF13696.6 GBG59476.1 - 0.58 10.0 1.8 1 9.3 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle PRKG1_interact PF15898.5 GBG59476.1 - 1.1 10.2 20.0 0.42 11.5 16.0 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Tho2 PF11262.8 GBG59476.1 - 1.8 7.7 8.7 3 7.0 8.7 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ALMT PF11744.8 GBG59476.1 - 7.4 5.3 7.0 12 4.6 7.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4246 PF14033.6 GBG59477.1 - 0.017 14.3 0.0 0.048 12.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4246) BUD22 PF09073.10 GBG59477.1 - 0.21 10.9 21.4 0.27 10.5 21.4 1.1 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 GBG59477.1 - 0.44 10.3 9.3 0.73 9.6 9.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG59477.1 - 0.59 8.8 8.6 0.81 8.4 8.6 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG59477.1 - 3.6 5.7 19.3 4.6 5.3 19.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG59477.1 - 5.1 6.4 12.9 8.2 5.8 12.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4551 PF15087.6 GBG59477.1 - 6.5 5.5 7.2 8.9 5.0 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Zip PF02535.22 GBG59477.1 - 7 5.8 8.2 9.9 5.3 8.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.12 GBG59477.1 - 9.5 5.5 21.7 13 5.1 21.7 1.1 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 GBG59478.1 - 1.7e-42 145.7 0.0 1.7e-42 145.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG59478.1 - 9.2e-32 109.1 0.0 2.5e-31 107.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59478.1 - 1.3e-29 102.5 0.0 2.7e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase_Tyr PF07714.17 GBG59478.1 - 2.5e-18 66.3 0.0 2.5e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Integrase_H2C2 PF17921.1 GBG59478.1 - 2.3e-14 53.2 0.1 5.7e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59478.1 - 0.011 15.3 0.2 1.2 8.6 0.0 2.5 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_ser-thr_kin PF05445.11 GBG59478.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 GBG59479.1 - 1e-70 238.2 0.0 1.4e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG59479.1 - 6e-46 156.8 0.0 8.7e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG59479.1 - 5.8e-06 25.3 0.0 1.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GBG59479.1 - 0.0025 17.2 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GBG59479.1 - 0.016 15.2 0.0 0.21 11.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2383 PF09537.10 GBG59480.1 - 0.1 13.0 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DUF4778 PF16008.5 GBG59483.1 - 0.037 14.1 1.4 0.051 13.6 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Presenilin PF01080.17 GBG59483.1 - 3.9 6.1 5.4 5.2 5.7 5.4 1.1 1 0 0 1 1 1 0 Presenilin Rota_NS53 PF00981.17 GBG59484.1 - 0.12 11.2 2.4 0.21 10.4 1.9 1.6 1 1 1 2 2 2 0 Rotavirus RNA-binding Protein 53 (NS53) RPW8 PF05659.11 GBG59484.1 - 0.24 11.1 4.9 3.1 7.5 0.4 2.6 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1664 PF07889.12 GBG59484.1 - 2.2 8.3 11.5 0.036 14.1 2.8 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) USP8_interact PF08941.10 GBG59484.1 - 3.7 7.3 8.2 0.2 11.5 2.4 1.9 2 0 0 2 2 2 0 USP8 interacting Mpp10 PF04006.12 GBG59485.1 - 0.054 12.0 17.6 0.07 11.6 17.6 1.2 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.12 GBG59485.1 - 0.11 11.8 17.0 0.15 11.4 17.0 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 GBG59485.1 - 1.2 8.2 26.1 1.4 8.0 26.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) KBP_C PF12309.8 GBG59485.1 - 1.5 8.2 6.3 1.6 8.2 6.3 1.0 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Vfa1 PF08432.10 GBG59485.1 - 1.8 8.9 7.9 2.1 8.6 7.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.10 GBG59485.1 - 2.1 7.6 21.2 2.6 7.3 21.2 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG59485.1 - 3.1 6.5 5.3 3 6.5 5.3 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 GBG59485.1 - 3.6 5.4 4.7 3.9 5.3 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nop14 PF04147.12 GBG59485.1 - 4.1 5.5 24.7 4.9 5.2 24.7 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 GBG59485.1 - 5.7 6.4 16.2 8 6.0 16.2 1.3 1 0 0 1 1 1 0 PPP4R2 DUF913 PF06025.12 GBG59485.1 - 6.3 5.7 5.0 7.2 5.5 5.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 GBG59485.1 - 8 5.8 27.1 9.6 5.5 27.1 1.1 1 0 0 1 1 1 0 SDA1 RT_RNaseH_2 PF17919.1 GBG59486.1 - 1.6e-32 111.5 0.0 3.3e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59486.1 - 3.5e-28 98.0 0.0 6.8e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59486.1 - 8.5e-17 61.0 0.4 1.6e-16 60.1 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59486.1 - 5.9e-11 42.3 0.1 3.2e-08 33.4 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG59486.1 - 0.69 8.1 5.4 1.3 7.2 5.4 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF3810 PF12725.7 GBG59487.1 - 3.3 7.0 7.3 1.8 7.8 4.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Myb_DNA-bind_4 PF13837.6 GBG59489.1 - 4.1e-09 36.7 0.6 3.7e-08 33.7 0.2 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG59489.1 - 0.0075 16.3 1.8 0.016 15.3 1.0 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain TMIE PF16038.5 GBG59489.1 - 0.014 15.3 1.0 0.029 14.2 1.0 1.4 1 0 0 1 1 1 0 TMIE protein CD34_antigen PF06365.12 GBG59489.1 - 0.034 13.7 0.2 0.073 12.6 0.2 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family Shisa PF13908.6 GBG59489.1 - 0.09 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator HemY_N PF07219.13 GBG59489.1 - 0.1 12.8 0.8 0.26 11.5 0.8 1.6 1 0 0 1 1 1 0 HemY protein N-terminus SIT PF15330.6 GBG59489.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM100 PF16311.5 GBG59489.1 - 0.16 11.5 1.7 0.32 10.6 1.7 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 DDE_Tnp_4 PF13359.6 GBG59490.1 - 6e-08 32.5 0.1 1.6e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG59490.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Peptidase_C14 PF00656.22 GBG59491.1 - 7.7e-10 39.1 0.0 2.5e-09 37.5 0.0 1.7 1 1 1 2 2 2 1 Caspase domain RT_RNaseH_2 PF17919.1 GBG59492.1 - 2e-32 111.2 0.0 3.7e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59492.1 - 4.1e-28 98.4 0.3 6.3e-28 97.8 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59492.1 - 2.3e-27 95.4 0.1 4e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NUDIX_4 PF14815.6 GBG59493.1 - 7e-05 22.8 0.0 0.00023 21.1 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Retrotrans_gag PF03732.17 GBG59493.1 - 0.0015 18.8 0.1 0.0034 17.6 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein EndIII_4Fe-2S PF10576.9 GBG59493.1 - 0.021 15.1 5.5 0.043 14.2 5.5 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Integrase_H2C2 PF17921.1 GBG59494.1 - 9.9e-20 70.4 0.1 1.8e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59494.1 - 1.2e-15 57.7 0.0 3.1e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG59494.1 - 0.02 14.6 0.0 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG59494.1 - 0.022 14.9 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger HhH-GPD PF00730.25 GBG59495.1 - 2.4e-10 40.8 0.0 9.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Retrotrans_gag PF03732.17 GBG59495.1 - 0.00048 20.3 0.5 0.0069 16.6 0.2 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein Retrotrans_gag PF03732.17 GBG59496.1 - 0.0004 20.6 3.1 0.0021 18.3 0.2 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein TFIIA PF03153.13 GBG59496.1 - 0.095 12.7 10.5 0.13 12.2 10.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 GBG59496.1 - 3 8.1 18.3 0.18 12.1 6.3 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA RT_RNaseH_2 PF17919.1 GBG59497.1 - 3.9e-13 49.3 0.0 9e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59497.1 - 3.1e-12 46.7 0.0 1.5e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59497.1 - 2.3e-09 37.1 0.0 3.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vma12 PF11712.8 GBG59497.1 - 0.13 12.3 0.1 0.43 10.7 0.1 1.9 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Csm1_N PF18504.1 GBG59497.1 - 0.56 10.6 3.1 3.3 8.1 3.1 2.4 1 0 0 1 1 1 0 Csm1 N-terminal domain Jnk-SapK_ap_N PF09744.9 GBG59497.1 - 1.3 9.2 13.3 0.027 14.7 5.3 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4637 PF15470.6 GBG59498.1 - 0.25 11.1 7.4 0.31 10.7 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SDA1 PF05285.12 GBG59498.1 - 0.3 10.5 8.0 0.32 10.4 8.0 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG59498.1 - 0.41 9.9 5.9 0.36 10.1 5.9 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG59498.1 - 0.64 8.2 9.7 0.68 8.1 9.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG59498.1 - 0.7 8.1 8.5 0.78 8.0 8.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 GBG59498.1 - 0.89 8.9 7.6 1 8.7 7.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CENP-B_dimeris PF09026.10 GBG59498.1 - 6.4 7.2 16.4 12 6.3 16.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 GBG59498.1 - 9.5 5.2 15.8 11 5.1 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LRR_6 PF13516.6 GBG59499.1 - 3.2e-12 45.4 2.8 0.023 14.7 0.1 6.4 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 GBG59499.1 - 0.00055 20.3 0.0 4.1 8.0 0.0 4.0 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) RT_RNaseH_2 PF17919.1 GBG59500.1 - 1.6e-31 108.3 0.0 3.4e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59500.1 - 7.5e-30 103.3 0.0 1.4e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59500.1 - 8.6e-14 51.6 0.2 1.9e-13 50.4 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG59500.1 - 0.015 14.9 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2990 PF11693.8 GBG59500.1 - 0.13 12.4 0.0 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) RVT_1 PF00078.27 GBG59501.1 - 4e-17 62.5 0.1 6.3e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG59501.1 - 2.1e-08 34.0 0.0 4.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59501.1 - 0.00096 19.8 0.0 0.0022 18.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59501.1 - 0.0074 16.8 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF3827 PF12877.7 GBG59501.1 - 0.034 12.6 0.5 0.066 11.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Snapin_Pallidin PF14712.6 GBG59501.1 - 0.23 11.9 0.1 0.23 11.9 0.1 2.9 3 0 0 3 3 3 0 Snapin/Pallidin NPV_P10 PF05531.12 GBG59501.1 - 3.2 8.3 6.0 1.1 9.8 0.4 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2398 PF09661.10 GBG59502.1 - 0.0015 17.9 0.1 0.0015 17.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2398) Tudor_3 PF18115.1 GBG59502.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Osmo_CC PF08946.10 GBG59502.1 - 0.24 11.7 2.0 0.39 11.0 0.2 2.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF1192 PF06698.11 GBG59502.1 - 1.8 8.7 5.1 4 7.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) F-box PF00646.33 GBG59503.1 - 7.6e-06 25.7 0.2 2.3e-05 24.1 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG59503.1 - 1.4e-05 24.8 0.3 1.4e-05 24.8 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box_5 PF18511.1 GBG59503.1 - 0.0013 18.2 0.1 0.0013 18.2 0.1 1.8 2 0 0 2 2 2 1 F-box LRR_6 PF13516.6 GBG59503.1 - 0.0028 17.6 0.1 5.6 7.3 0.2 4.7 5 0 0 5 5 5 1 Leucine Rich repeat RVT_1 PF00078.27 GBG59504.1 - 1.7e-26 93.2 0.0 2.7e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG59504.1 - 1e-08 35.7 0.0 2.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59504.1 - 1.3e-08 34.7 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG59504.1 - 6.3e-08 32.8 0.0 1.9e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG59504.1 - 1.3e-06 28.9 0.0 2.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG59504.1 - 0.0073 16.2 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG59504.1 - 0.0083 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease SNARE_assoc PF09335.11 GBG59505.1 - 3.7e-07 30.6 0.0 1.4e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF1772 PF08592.11 GBG59505.1 - 0.019 15.3 0.1 0.2 12.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) EphA2_TM PF14575.6 GBG59505.1 - 0.039 14.8 0.0 23 6.0 0.0 3.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4288 PF14119.6 GBG59506.1 - 0.41 11.1 3.5 1.6 9.2 3.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) LAT PF15234.6 GBG59506.1 - 2.6 7.7 5.6 6.4 6.4 5.6 1.6 1 0 0 1 1 1 0 Linker for activation of T-cells RVT_1 PF00078.27 GBG59507.1 - 6.1e-21 75.0 0.0 1.4e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59507.1 - 1.4e-17 63.6 0.1 4e-17 62.1 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG59507.1 - 9.6e-16 58.0 0.4 2.7e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59507.1 - 1.3e-10 41.5 0.0 4.1e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG59507.1 - 3.5e-10 39.8 0.0 1e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59507.1 - 0.0024 18.1 0.0 0.0024 18.1 0.0 3.7 5 0 0 5 5 5 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG59507.1 - 0.62 10.6 2.0 1.5 9.4 0.1 2.4 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 GBG59507.1 - 2 8.9 4.7 4.4 7.8 0.1 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper CLZ PF16526.5 GBG59507.1 - 6.2 7.3 8.1 6.2 7.3 1.9 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CAP160 PF07918.11 GBG59507.1 - 7.5 6.4 8.2 25 4.7 1.1 2.8 2 0 0 2 2 2 0 CAP160 repeat HIP1_clath_bdg PF16515.5 GBG59507.1 - 8.7 7.0 15.3 0.055 14.1 3.4 3.1 4 0 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KRTAP PF11759.8 GBG59509.1 - 0.0094 16.5 5.8 0.0094 16.5 5.8 3.0 2 1 0 2 2 2 1 Keratin-associated matrix PHD PF00628.29 GBG59510.1 - 0.00039 20.3 4.8 0.0012 18.7 4.8 1.9 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 GBG59510.1 - 0.058 13.3 1.0 0.22 11.4 1.0 1.9 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 GBG59510.1 - 0.23 11.1 3.9 0.66 9.6 3.9 1.8 1 0 0 1 1 1 0 PHD-finger GPS2_interact PF15784.5 GBG59510.1 - 0.7 10.4 5.8 0.75 10.3 1.9 2.9 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain GPS2_interact PF15784.5 GBG59511.1 - 0.68 10.4 5.8 0.73 10.3 1.9 2.9 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain PP2C_C PF07830.13 GBG59511.1 - 1.3 9.5 3.2 1 9.9 0.4 2.3 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF3153 PF11353.8 GBG59512.1 - 0.02 14.5 0.8 0.02 14.5 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3153) UPF0242 PF06785.11 GBG59512.1 - 0.12 12.5 20.5 0.18 11.9 20.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF739 PF05339.11 GBG59512.1 - 0.19 11.9 2.2 1.2 9.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF739) Sas6_CC PF18594.1 GBG59512.1 - 0.23 11.3 0.4 0.23 11.3 0.4 3.4 4 1 0 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain FRG PF08867.11 GBG59512.1 - 0.26 12.3 4.5 0.29 12.1 0.3 2.2 2 0 0 2 2 2 0 FRG domain ALMT PF11744.8 GBG59512.1 - 0.33 9.7 12.5 0.42 9.4 12.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CheZ PF04344.13 GBG59512.1 - 0.58 10.0 13.1 3.4 7.5 13.1 1.8 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ CspB_prodomain PF18425.1 GBG59512.1 - 0.73 9.9 6.9 4.2 7.4 0.8 2.3 1 1 1 2 2 2 0 Csp protease B prodomain YtxH PF12732.7 GBG59512.1 - 1.3 9.6 6.6 14 6.3 6.6 2.3 1 1 0 1 1 1 0 YtxH-like protein BRE1 PF08647.11 GBG59512.1 - 2.8 8.1 23.7 2 8.6 13.7 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF5595 PF18077.1 GBG59512.1 - 4.9 7.3 12.9 1.8 8.7 3.9 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF5595) DUF1664 PF07889.12 GBG59512.1 - 7.1 6.7 13.5 2.2 8.3 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1283 PF06932.11 GBG59512.1 - 8.5 6.7 10.3 0.52 10.5 3.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1283) RVT_1 PF00078.27 GBG59513.1 - 1.2e-29 103.4 0.0 2.4e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59513.1 - 1.3e-25 89.7 0.0 2.6e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59513.1 - 3.1e-25 88.1 0.0 6.2e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59513.1 - 1.2e-20 73.4 0.2 2.5e-20 72.3 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59513.1 - 4e-10 39.9 0.2 1.4e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG59513.1 - 0.0045 17.2 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG59513.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 GBG59513.1 - 0.017 15.0 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF3560 PF12083.8 GBG59513.1 - 0.09 12.9 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) CASP_C PF08172.12 GBG59515.1 - 2.2e-60 204.1 0.0 2.2e-60 204.1 0.0 4.7 4 2 1 5 5 5 2 CASP C terminal BRE1 PF08647.11 GBG59515.1 - 0.049 13.7 0.6 0.049 13.7 0.6 6.6 6 1 1 7 7 7 0 BRE1 E3 ubiquitin ligase PPR PF01535.20 GBG59516.1 - 1.1e-114 366.9 42.7 1.9e-09 37.1 0.1 17.4 17 0 0 17 17 17 17 PPR repeat PPR_2 PF13041.6 GBG59516.1 - 3.2e-110 360.2 22.5 1.5e-14 53.9 0.1 16.8 5 4 13 18 18 18 16 PPR repeat family PPR_1 PF12854.7 GBG59516.1 - 1.9e-106 347.4 2.0 6.6e-09 35.3 0.0 16.9 17 0 0 17 17 17 14 PPR repeat PPR_3 PF13812.6 GBG59516.1 - 1.5e-82 271.6 2.7 4.9e-11 42.5 0.0 13.5 9 3 5 15 15 15 11 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG59516.1 - 7.4e-41 139.9 10.4 2e-09 37.1 0.7 7.7 3 3 5 8 8 8 7 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG59516.1 - 1.5e-09 38.2 26.5 0.08 13.5 0.0 8.5 7 3 3 10 10 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 GBG59516.1 - 1.2e-08 35.0 21.7 1.6 9.8 0.0 9.8 8 2 2 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG59516.1 - 0.0017 18.3 14.5 7.8 6.8 0.6 8.5 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_4 PF07721.14 GBG59516.1 - 0.0019 18.6 10.3 19 6.3 0.2 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat Clathrin PF00637.20 GBG59516.1 - 0.0056 16.6 2.3 9.7 6.1 1.1 5.9 6 3 1 7 7 7 0 Region in Clathrin and VPS TPR_16 PF13432.6 GBG59516.1 - 0.0058 17.2 15.3 13 6.6 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG59516.1 - 0.006 16.7 20.6 3.1 8.2 0.0 7.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG59516.1 - 0.0098 16.2 13.5 8.5 6.8 0.1 7.7 9 1 0 9 9 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GBG59516.1 - 0.01 15.8 10.8 3 7.7 0.1 6.4 7 0 0 7 7 7 0 Virulence factor membrane-bound polymerase, C-terminal SPOB_a PF14689.6 GBG59516.1 - 0.065 13.0 9.0 31 4.4 0.0 6.4 7 1 1 8 8 7 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_10 PF13374.6 GBG59516.1 - 0.3 11.0 13.1 8.4 6.4 0.2 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Nop53 PF07767.11 GBG59516.1 - 0.39 10.1 10.8 0.81 9.0 10.8 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Exog_C PF18026.1 GBG59516.1 - 0.47 10.6 9.2 7.9 6.6 0.0 6.4 9 0 0 9 9 8 0 Endo/exonuclease (EXOG) C-terminal domain DUF4473 PF14747.6 GBG59516.1 - 0.58 10.7 3.1 46 4.7 0.1 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF4473) TPR_17 PF13431.6 GBG59516.1 - 1.6 9.3 5.0 14 6.4 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG59516.1 - 1.6 8.6 19.5 5.3 7.0 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat FAM176 PF14851.6 GBG59516.1 - 2 8.1 12.8 18 5.0 6.2 3.7 4 0 0 4 4 4 0 FAM176 family Proteasome PF00227.26 GBG59517.1 - 6.4e-29 100.8 0.0 8.4e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Plavaka PF18759.1 GBG59518.1 - 1.3e-27 96.9 1.5 1.9e-27 96.4 0.3 1.9 2 0 0 2 2 2 1 Plavaka transposase Histone PF00125.24 GBG59518.1 - 3.6e-20 72.7 1.7 3.6e-20 72.7 1.7 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF2284 PF10050.9 GBG59518.1 - 0.091 12.5 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) zf-CRD PF17979.1 GBG59519.1 - 3.6e-32 111.7 1.5 3.6e-32 111.7 1.5 2.0 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 GBG59519.1 - 2.9e-12 46.8 0.0 6.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 GBG59519.1 - 1.8e-06 28.1 0.0 4.8e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-CCHH PF10283.9 GBG59519.1 - 1.9e-05 24.5 1.7 4.7e-05 23.3 1.7 1.7 1 0 0 1 1 1 1 PBZ domain zf-CRD PF17979.1 GBG59520.1 - 3.6e-32 111.7 1.5 3.6e-32 111.7 1.5 2.0 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 GBG59520.1 - 2.8e-12 46.8 0.0 6.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 GBG59520.1 - 1.8e-06 28.1 0.0 4.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-CCHH PF10283.9 GBG59520.1 - 1.9e-05 24.5 1.7 4.7e-05 23.3 1.7 1.7 1 0 0 1 1 1 1 PBZ domain DUF1232 PF06803.12 GBG59521.1 - 3.5e-08 33.1 9.6 5.4e-08 32.5 9.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) zf-RING_UBOX PF13445.6 GBG59521.1 - 8.7e-08 32.1 5.8 2.2e-07 30.8 3.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GBG59521.1 - 1.1e-07 31.9 9.3 2.1e-07 31.0 9.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GBG59521.1 - 3.8e-07 29.9 8.8 7e-07 29.0 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG59521.1 - 1.3e-06 28.2 8.0 1.9e-06 27.6 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG59521.1 - 3.3e-06 26.8 9.2 1e-05 25.3 9.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG59521.1 - 7.7e-05 22.9 12.5 0.00013 22.2 12.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG59521.1 - 0.0018 18.2 7.7 0.0039 17.1 7.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG59521.1 - 0.008 16.0 9.7 0.016 15.0 9.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_13 PF17977.1 GBG59521.1 - 0.025 14.7 3.4 0.045 13.9 3.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tmemb_55A PF09788.9 GBG59521.1 - 0.13 11.3 2.8 0.21 10.6 2.8 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A Baculo_IE-1 PF05290.11 GBG59521.1 - 0.91 9.5 5.4 1.5 8.8 5.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 GBG59521.1 - 1.5 8.9 7.5 64 3.7 7.5 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 GBG59521.1 - 5 7.3 7.7 6.3 7.0 5.8 2.0 1 1 1 2 2 2 0 zinc RING finger of MSL2 Trehalose_PPase PF02358.16 GBG59522.1 - 1.1e-46 158.9 0.0 1.1e-40 139.3 0.0 2.3 1 1 1 2 2 2 2 Trehalose-phosphatase SMC_N PF02463.19 GBG59523.1 - 6e-35 120.7 0.0 7.8e-35 120.3 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GBG59523.1 - 1.8e-27 95.9 0.0 7.4e-27 94.0 0.0 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 GBG59523.1 - 2.9e-15 57.3 24.0 1.5e-12 48.4 24.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 GBG59523.1 - 1.3e-12 48.2 10.8 2.5e-12 47.2 10.8 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GBG59523.1 - 1.8e-09 37.2 0.0 4.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GBG59523.1 - 1e-08 35.3 0.7 1.7e-08 34.6 0.1 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF2347 PF09804.9 GBG59523.1 - 0.0055 16.3 1.3 0.01 15.5 1.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) ABC_tran PF00005.27 GBG59523.1 - 0.012 16.2 0.0 0.012 16.2 0.0 3.3 3 1 0 3 3 2 0 ABC transporter AAA_27 PF13514.6 GBG59523.1 - 0.14 11.7 9.7 0.24 11.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain G10 PF01125.17 GBG59523.1 - 0.43 10.3 8.2 1 9.1 0.8 2.5 2 0 0 2 2 2 0 G10 protein Vfa1 PF08432.10 GBG59523.1 - 9.6 6.5 18.3 4.5 7.6 6.4 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF659 PF04937.15 GBG59524.1 - 2.5e-20 72.9 0.0 3.1e-15 56.4 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59524.1 - 3.2e-06 26.8 0.1 8.2e-06 25.5 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SMC_N PF02463.19 GBG59525.1 - 0.0014 18.1 13.3 0.0034 16.9 13.3 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain BSP_II PF05432.11 GBG59525.1 - 0.0063 16.2 41.0 0.0063 16.2 41.0 2.5 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Laminin_II PF06009.12 GBG59525.1 - 0.39 10.7 31.7 0.042 13.9 5.7 4.2 2 1 2 4 4 4 0 Laminin Domain II DUF948 PF06103.11 GBG59525.1 - 0.87 9.9 9.4 13 6.1 1.6 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 GBG59525.1 - 1.3 9.5 18.2 16 6.0 2.5 6.2 4 2 1 6 6 6 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 GBG59525.1 - 6.8 6.8 34.5 1.4 9.0 2.3 4.9 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GBG59525.1 - 7.1 6.7 13.6 3 7.9 3.2 3.5 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Clathrin_lg_ch PF01086.17 GBG59526.1 - 7.3e-17 62.2 0.6 1.3e-12 48.3 0.1 2.2 2 0 0 2 2 2 2 Clathrin light chain DUF659 PF04937.15 GBG59527.1 - 0.00023 21.0 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-FCS PF06467.14 GBG59527.1 - 0.048 13.6 3.1 0.098 12.6 3.1 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Clathrin_lg_ch PF01086.17 GBG59528.1 - 1.6e-10 41.4 7.3 1e-06 29.0 4.7 2.1 2 0 0 2 2 2 2 Clathrin light chain Clathrin_lg_ch PF01086.17 GBG59529.1 - 1.2e-16 61.5 0.6 2e-12 47.6 0.1 2.2 2 0 0 2 2 2 2 Clathrin light chain VDE PF07137.11 GBG59530.1 - 1.2e-96 322.9 1.2 1.6e-96 322.5 1.2 1.2 1 0 0 1 1 1 1 VDE lipocalin domain DUF4247 PF14042.6 GBG59530.1 - 0.18 12.5 0.1 0.33 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) Shugoshin_C PF07557.11 GBG59531.1 - 0.00049 19.8 9.8 0.00049 19.8 9.8 3.8 4 0 0 4 4 4 1 Shugoshin C terminus APG6_N PF17675.1 GBG59531.1 - 0.058 13.9 12.8 0.081 13.5 9.6 2.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 GBG59531.1 - 4.7 6.2 14.6 16 4.5 14.6 1.8 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 GBG59531.1 - 5 7.8 8.8 4.2 8.1 3.4 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Herpes_BLRF2 PF05812.12 GBG59532.1 - 0.014 15.5 1.5 0.024 14.8 0.3 2.0 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein BRCT_2 PF16589.5 GBG59533.1 - 2e-07 31.3 0.0 9.4e-05 22.7 0.0 3.4 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 GBG59533.1 - 2.4e-05 24.3 0.0 0.00063 19.8 0.0 2.9 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 GBG59533.1 - 7.1e-05 23.1 0.0 0.14 12.5 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 GBG59533.1 - 0.014 15.2 0.0 0.068 13.1 0.0 2.2 1 1 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain HCMV_UL139 PF12507.8 GBG59533.1 - 8.6 6.8 7.8 3.6 8.0 0.1 3.4 3 0 0 3 3 3 0 Human Cytomegalovirus UL139 protein RT_RNaseH_2 PF17919.1 GBG59534.1 - 1.9e-34 117.7 0.0 3.6e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59534.1 - 8.6e-30 103.1 0.0 1.9e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59534.1 - 8.5e-29 100.6 0.0 1.5e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59534.1 - 2.1e-17 63.0 0.5 4.4e-17 61.9 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG59534.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG59535.1 - 4.2e-33 113.3 0.0 1.2e-32 111.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59535.1 - 9.2e-29 99.8 0.0 2.8e-28 98.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59535.1 - 3.3e-21 75.8 0.1 6.4e-10 38.9 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59535.1 - 6e-18 64.7 0.3 1.5e-17 63.4 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG59535.1 - 0.033 14.5 0.7 0.13 12.6 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Snapin_Pallidin PF14712.6 GBG59535.1 - 0.32 11.4 2.1 0.47 10.9 0.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin RVT_1 PF00078.27 GBG59536.1 - 4.2e-32 111.5 0.0 6.3e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59536.1 - 5.8e-23 80.8 0.0 1.5e-16 60.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59536.1 - 1.2e-12 47.7 0.0 2.2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59536.1 - 5e-12 46.1 0.0 1.7e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG59536.1 - 1.4e-10 41.4 0.0 3.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG59536.1 - 0.00097 19.3 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Toxin_23 PF08093.11 GBG59537.1 - 0.12 12.5 9.3 0.12 12.6 7.5 2.0 2 1 0 2 2 2 0 Magi 5 toxic peptide family RVP_2 PF08284.11 GBG59539.1 - 1.9e-08 34.2 0.0 4.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59539.1 - 5.3e-07 30.2 0.0 1.7e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59539.1 - 3.7e-06 27.4 0.0 8.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG59539.1 - 0.011 16.0 0.2 0.059 13.6 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG59539.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Trimer_CC PF08954.11 GBG59539.1 - 0.21 11.1 2.4 3.3 7.3 0.9 3.2 2 1 1 3 3 3 0 Trimerisation motif TolA_bind_tri PF16331.5 GBG59539.1 - 0.8 9.8 4.5 0.43 10.7 1.2 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation RVT_1 PF00078.27 GBG59540.1 - 2.5e-32 112.2 0.1 4.9e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59540.1 - 7.2e-30 103.0 0.0 2.4e-29 101.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59540.1 - 4.5e-29 100.8 0.4 1.7e-28 98.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG59540.1 - 0.039 13.6 0.1 0.039 13.6 0.1 3.2 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase PIF1 PF05970.14 GBG59541.1 - 6.7e-15 55.1 0.0 1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Plasmodium_Vir PF05795.11 GBG59542.1 - 0.0039 16.7 4.1 0.51 9.7 0.0 2.3 2 0 0 2 2 2 1 Plasmodium vivax Vir protein BUD22 PF09073.10 GBG59542.1 - 0.0049 16.3 6.4 0.0049 16.3 6.4 2.8 2 1 0 2 2 2 1 BUD22 CLN3 PF02487.17 GBG59542.1 - 0.031 13.3 1.2 3.6 6.5 0.5 2.3 2 0 0 2 2 2 0 CLN3 protein Zip PF02535.22 GBG59542.1 - 0.44 9.7 5.5 12 5.0 2.9 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter DUF913 PF06025.12 GBG59542.1 - 0.87 8.5 10.6 2.8 6.8 5.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TLP-20 PF06088.11 GBG59542.1 - 0.87 9.5 15.5 1.3 8.9 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SpoIIP PF07454.11 GBG59542.1 - 1.7 8.1 17.6 3 7.2 8.6 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF3506 PF12014.8 GBG59542.1 - 3.6 7.6 5.5 2.8 7.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) SDA1 PF05285.12 GBG59542.1 - 5.3 6.4 54.4 0.037 13.5 22.7 3.4 4 0 0 4 4 4 0 SDA1 Folate_carrier PF01770.18 GBG59542.1 - 5.8 5.5 5.2 3.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Reduced folate carrier Myc_N PF01056.18 GBG59542.1 - 6.1 6.6 19.9 4.8 7.0 2.7 2.5 2 0 0 2 2 2 0 Myc amino-terminal region DUF4834 PF16118.5 GBG59542.1 - 7.5 7.6 12.0 21 6.2 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CENP-K PF11802.8 GBG59543.1 - 0.0037 16.9 2.9 0.0068 16.0 2.9 1.4 1 1 0 1 1 1 1 Centromere-associated protein K Troponin PF00992.20 GBG59543.1 - 0.011 16.0 5.1 0.3 11.4 0.6 2.4 2 0 0 2 2 2 0 Troponin DUF3499 PF12005.8 GBG59543.1 - 0.27 11.9 12.7 0.49 11.0 2.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3499) CREPT PF16566.5 GBG59543.1 - 0.96 9.6 8.6 1.3 9.1 2.3 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1635 PF07795.11 GBG59543.1 - 1.2 8.9 10.1 0.073 12.9 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) RVT_1 PF00078.27 GBG59544.1 - 1.4e-70 237.3 1.6 4.2e-26 91.8 0.2 3.5 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59544.1 - 4.6e-63 209.5 0.0 4.9e-30 103.5 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59544.1 - 2.7e-56 188.3 0.1 7.2e-27 93.7 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59544.1 - 5.7e-17 61.6 0.1 1.4e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59544.1 - 9.7e-13 48.4 0.0 3.8e-12 46.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG59544.1 - 8.3e-06 26.3 0.2 4.9e-05 23.8 0.0 2.6 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease BUD22 PF09073.10 GBG59544.1 - 3.1e-05 23.5 17.3 3.1e-05 23.5 17.3 4.3 3 1 1 4 4 3 1 BUD22 RVP_2 PF08284.11 GBG59544.1 - 0.00011 22.0 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease AP3D1 PF06375.11 GBG59544.1 - 0.00043 20.5 20.2 0.00043 20.5 20.2 5.4 5 1 1 7 7 2 1 AP-3 complex subunit delta-1 BSP_II PF05432.11 GBG59544.1 - 0.0027 17.4 22.1 0.0027 17.4 22.1 3.5 2 1 0 3 3 1 1 Bone sialoprotein II (BSP-II) zf-CCHC_3 PF13917.6 GBG59544.1 - 0.0031 17.4 1.5 0.0084 16.1 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG59544.1 - 0.0059 17.2 0.0 0.034 14.8 0.0 2.5 2 0 0 2 2 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG59544.1 - 0.0085 16.3 10.4 1.6 9.0 0.4 5.1 5 0 0 5 5 5 2 Retrotransposon gag protein DUF1758 PF05585.12 GBG59544.1 - 0.098 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 GBG59545.1 - 7e-19 67.7 0.2 1.4e-18 66.7 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG59545.1 - 1.3e-11 44.7 0.1 3.2e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59545.1 - 3.5e-10 40.1 0.0 1.1e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG59545.1 - 0.0041 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59545.1 - 0.027 14.7 0.1 0.078 13.3 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG59545.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG59546.1 - 4.3e-16 58.8 0.5 8.2e-15 54.7 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG59546.1 - 0.0011 19.2 1.3 0.0088 16.2 0.2 2.7 2 0 0 2 2 2 1 H2C2 zinc finger zf-CCHC_2 PF13696.6 GBG59546.1 - 0.5 10.2 6.6 0.075 12.9 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG59546.1 - 6.1 7.1 5.2 0.79 9.9 0.6 2.0 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG59547.1 - 1.3e-31 108.6 0.0 4.8e-16 58.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59547.1 - 1.1e-29 102.8 0.0 2.1e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59547.1 - 3.4e-28 98.7 0.0 5.6e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59547.1 - 0.0021 18.1 0.1 0.0045 17.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59549.1 - 2.8e-28 98.9 0.1 4.5e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59549.1 - 5.5e-24 84.5 0.0 1.5e-23 83.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59549.1 - 4.8e-23 81.1 0.0 1.8e-22 79.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59549.1 - 2.1e-07 31.4 0.0 3.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG59549.1 - 4.4e-06 26.5 0.0 7.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG59549.1 - 5.1e-06 27.0 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59549.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DsrH PF04077.12 GBG59550.1 - 0.00016 21.8 21.1 49 4.1 0.1 12.5 8 5 9 17 17 17 2 DsrH like protein CstA PF02554.14 GBG59550.1 - 0.61 8.9 8.4 40 2.9 0.1 6.3 6 1 0 7 7 7 0 Carbon starvation protein CstA RVT_1 PF00078.27 GBG59552.1 - 4.6e-16 59.0 0.0 1.6e-15 57.2 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59552.1 - 1.5e-15 57.3 0.0 3.1e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59552.1 - 6.7e-14 51.7 0.0 1.5e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59552.1 - 0.0014 18.7 0.8 0.0092 16.1 0.8 2.3 1 1 0 1 1 1 1 Integrase zinc binding domain APG17 PF04108.12 GBG59552.1 - 0.003 16.8 0.1 0.0064 15.6 0.1 1.5 1 0 0 1 1 1 1 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG59553.1 - 1.4e-32 111.7 0.0 3.6e-32 110.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59553.1 - 2.3e-29 101.8 0.3 7.8e-29 100.1 0.3 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59553.1 - 2.4e-14 53.5 0.0 6.2e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG59553.1 - 8.3e-10 38.6 0.3 1.8e-09 37.5 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain TBCA PF02970.16 GBG59553.1 - 1.1 9.7 4.3 0.43 11.0 0.5 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A zf-CCHC_3 PF13917.6 GBG59554.1 - 0.00037 20.4 1.0 0.00078 19.4 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG59554.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein DUF3863 PF12979.7 GBG59554.1 - 0.014 14.3 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) zf-CCHC PF00098.23 GBG59554.1 - 1.5 9.0 3.7 2.5 8.3 3.7 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG59555.1 - 2.2e-22 78.9 0.0 4.6e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59555.1 - 5.3e-22 78.1 0.0 8.2e-21 74.3 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59555.1 - 2e-14 53.4 0.0 5.1e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59555.1 - 2.7e-06 27.1 0.0 5.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG59555.1 - 0.0014 19.1 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG59555.1 - 0.0016 18.8 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59555.1 - 0.0016 18.2 0.5 0.0052 16.6 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease rve PF00665.26 GBG59555.1 - 0.0046 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG59555.1 - 0.0075 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG59555.1 - 0.027 14.7 0.1 0.077 13.3 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG59556.1 - 1.5e-14 53.8 0.1 2.4e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain XendoU PF09412.10 GBG59556.1 - 1.2 8.3 8.0 15 4.7 0.0 4.3 3 1 3 6 6 6 0 Endoribonuclease XendoU SeleniumBinding PF11524.8 GBG59556.1 - 1.6 9.3 17.2 29 5.2 0.2 6.3 1 1 6 7 7 7 0 Selenium binding protein RT_RNaseH_2 PF17919.1 GBG59557.1 - 8.1e-28 96.4 0.0 1.5e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59557.1 - 4.4e-26 91.2 0.1 2.9e-25 88.6 0.0 2.4 4 0 0 4 4 4 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG59557.1 - 7.8e-06 25.7 3.2 1.5e-05 24.8 3.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG59557.1 - 5.8e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59557.1 - 0.00017 22.0 0.0 0.00034 21.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59557.1 - 0.00029 20.6 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59557.1 - 0.0051 16.6 0.1 0.0089 15.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG59557.1 - 0.018 14.8 4.1 0.03 14.1 4.1 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG59558.1 - 1.7e-23 82.6 0.0 3.5e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59558.1 - 7.1e-20 71.3 0.1 4.2e-19 68.8 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59558.1 - 1.4e-08 35.0 0.0 3.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG59558.1 - 0.0028 17.2 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59558.1 - 0.0082 16.2 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG59558.1 - 0.0094 16.5 0.0 0.025 15.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59558.1 - 0.013 16.2 0.0 0.037 14.7 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG59558.1 - 0.071 13.4 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG59559.1 - 5.7e-48 163.4 0.0 9.2e-31 107.1 0.0 3.6 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59559.1 - 1.1e-25 89.5 0.0 3.2e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59559.1 - 2.5e-16 59.9 0.0 6.7e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59559.1 - 2.1e-07 31.4 0.1 4.6e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG59559.1 - 5.4e-07 29.8 0.0 1.4e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG59559.1 - 2.3e-05 25.0 0.1 0.00083 20.0 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG59559.1 - 0.0016 18.2 1.6 0.03 14.1 0.9 2.8 3 0 0 3 3 3 1 Aspartyl protease RVP PF00077.20 GBG59559.1 - 0.0058 16.9 0.1 0.78 10.1 0.0 2.6 2 0 0 2 2 2 1 Retroviral aspartyl protease rve_3 PF13683.6 GBG59559.1 - 0.017 14.9 0.0 0.054 13.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG59560.1 - 2e-23 83.1 0.1 4.4e-23 81.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59560.1 - 2.2e-17 62.9 0.1 4.4e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59560.1 - 8.6e-08 32.4 0.3 4.4e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG59560.1 - 1.8e-05 24.5 0.0 4.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59560.1 - 2.1e-05 25.1 0.0 6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59560.1 - 6.6e-05 23.4 0.1 0.00019 21.9 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG59560.1 - 0.012 15.9 0.1 0.12 12.7 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG59560.1 - 0.15 12.1 0.8 0.38 10.9 0.8 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation zf-RVT PF13966.6 GBG59561.1 - 9.3e-05 23.1 0.6 0.00036 21.2 0.6 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DNA_pol_B PF00136.21 GBG59561.1 - 0.32 9.6 5.0 0.85 8.3 5.0 1.7 1 0 0 1 1 1 0 DNA polymerase family B Mito_fiss_reg PF05308.11 GBG59562.1 - 0.0049 17.0 1.7 0.0088 16.1 1.7 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator DivIC PF04977.15 GBG59562.1 - 0.11 12.3 0.3 0.11 12.3 0.3 3.6 3 1 1 4 4 4 0 Septum formation initiator ADIP PF11559.8 GBG59562.1 - 0.16 12.0 10.1 0.22 11.6 6.7 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 GBG59562.1 - 0.35 10.9 3.4 5.9 6.9 0.6 2.4 2 0 0 2 2 2 0 FlxA-like protein KELK PF15796.5 GBG59562.1 - 2.9 8.4 15.1 0.58 10.7 6.7 2.7 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Seryl_tRNA_N PF02403.22 GBG59562.1 - 4.1 7.7 12.0 0.82 9.9 4.2 2.8 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.8 GBG59562.1 - 7.8 6.8 13.4 23 5.3 7.9 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding RT_RNaseH PF17917.1 GBG59565.1 - 1.1e-27 96.3 0.0 2.3e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59565.1 - 1.8e-25 88.9 0.0 4.2e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG59565.1 - 0.054 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG59565.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG59566.1 - 8.9e-35 120.2 0.1 1.5e-34 119.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59566.1 - 7.7e-29 99.7 0.0 2.5e-28 98.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59566.1 - 1.7e-17 63.6 0.0 5.2e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59567.1 - 0.00091 19.5 0.9 0.017 15.3 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG59567.1 - 0.011 15.7 2.7 0.027 14.4 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Trypan_PARP PF05887.11 GBG59569.1 - 0.00078 19.4 6.9 0.00078 19.4 6.9 1.6 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 GBG59569.1 - 2.3 7.8 9.9 8.5 5.9 9.9 1.8 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Retrotrans_gag PF03732.17 GBG59570.1 - 0.0027 18.0 0.1 0.0059 16.9 0.1 1.5 1 1 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG59571.1 - 5.8e-28 97.9 0.1 1.1e-27 97.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG59571.1 - 3e-20 72.5 0.0 5.8e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 GBG59571.1 - 3.5e-18 65.5 0.0 8e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Plant_tran PF04827.14 GBG59571.1 - 2.3e-11 43.7 0.0 4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein RT_RNaseH PF17917.1 GBG59571.1 - 3.8e-10 40.0 0.0 8.9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_1 PF01609.21 GBG59571.1 - 0.052 13.2 0.8 0.26 10.9 0.5 2.3 3 0 0 3 3 3 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG59572.1 - 6.3e-10 39.3 0.9 6.3e-10 39.3 0.9 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain gag-asp_proteas PF13975.6 GBG59572.1 - 0.0008 19.9 0.0 0.0026 18.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG59572.1 - 0.0027 18.0 0.0 0.0079 16.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59572.1 - 0.0069 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG59572.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MADF_DNA_bdg PF10545.9 GBG59572.1 - 0.014 15.7 0.1 0.014 15.7 0.1 2.8 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Asp_protease_2 PF13650.6 GBG59572.1 - 0.042 14.5 0.0 0.14 12.8 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Myb_DNA-bind_6 PF13921.6 GBG59572.1 - 1.1 9.6 3.1 3.2 8.1 0.1 2.9 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG59572.1 - 1.7 8.8 5.5 0.42 10.7 1.0 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RT_RNaseH PF17917.1 GBG59573.1 - 2.5e-19 69.5 0.4 8.2e-19 67.8 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59573.1 - 6e-17 61.5 0.0 7.9e-16 57.9 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG59573.1 - 0.014 15.4 1.2 0.028 14.5 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DDHD PF02862.17 GBG59573.1 - 5.9 7.0 10.2 0.25 11.5 3.3 2.1 1 1 1 2 2 2 0 DDHD domain CENP-Q PF13094.6 GBG59574.1 - 0.00025 21.3 2.3 0.00025 21.3 2.3 1.8 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit WDCP PF15390.6 GBG59574.1 - 0.068 11.6 0.5 0.11 10.9 0.5 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF5584 PF17822.1 GBG59575.1 - 0.33 10.4 0.1 0.48 9.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5584) TYW3 PF02676.14 GBG59576.1 - 6.3e-61 205.4 0.0 1.3e-60 204.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase TYW3 Apolipoprotein PF01442.18 GBG59576.1 - 0.0087 16.0 1.4 0.0087 16.0 1.4 1.5 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF2207 PF09972.9 GBG59576.1 - 0.063 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPX PF03105.19 GBG59576.1 - 0.12 12.3 8.1 0.6 10.0 0.1 2.3 2 0 0 2 2 2 0 SPX domain LapA_dom PF06305.11 GBG59576.1 - 0.27 11.1 1.8 0.86 9.5 1.8 1.9 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain REV PF00424.18 GBG59576.1 - 0.96 9.5 6.0 0.25 11.4 0.1 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Antifungal_prot PF11402.8 GBG59577.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Antifungal protein TAF4 PF05236.14 GBG59578.1 - 1.1e-50 173.0 9.3 1.1e-50 173.0 9.3 8.6 9 2 1 10 10 10 1 Transcription initiation factor TFIID component TAF4 family RVT_1 PF00078.27 GBG59578.1 - 4.6e-27 95.0 0.0 1.3e-26 93.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59578.1 - 5.4e-20 71.6 0.0 2.2e-19 69.7 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59578.1 - 8.8e-15 54.6 0.0 1.8e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG59578.1 - 2.5e-13 49.9 0.0 1.1e-12 47.8 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59578.1 - 3.2e-10 39.9 0.0 5.2e-07 29.5 0.0 2.8 3 0 0 3 3 3 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59578.1 - 1.3e-08 35.4 0.0 8e-08 32.8 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59578.1 - 5.8e-06 26.8 0.0 3e-05 24.5 0.0 2.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG59578.1 - 0.03 14.1 0.0 0.086 12.6 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease TAF PF02969.17 GBG59578.1 - 0.072 13.3 0.2 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) RVT_1 PF00078.27 GBG59580.1 - 1.2e-31 110.0 0.1 1.9e-31 109.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59580.1 - 3.8e-16 59.0 0.0 8.2e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59580.1 - 8.3e-12 45.0 1.0 1.9e-11 43.9 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG59580.1 - 1.5e-08 34.9 0.0 8.5e-08 32.4 0.0 2.1 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59580.1 - 2.3e-07 31.0 0.0 7.2e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG59580.1 - 3.2e-07 30.8 0.0 6.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59580.1 - 5.1e-07 30.3 0.0 1.1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59580.1 - 8.7e-07 28.8 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59580.1 - 5.9e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease YcgR PF07317.12 GBG59581.1 - 0.015 15.2 0.9 0.032 14.1 0.9 1.5 1 0 0 1 1 1 0 Flagellar regulator YcgR RT_RNaseH_2 PF17919.1 GBG59582.1 - 4.2e-23 81.3 0.0 9.8e-23 80.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59582.1 - 1.6e-19 70.1 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59582.1 - 3.6e-17 62.6 0.1 5e-11 42.5 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG59582.1 - 1.1e-07 32.4 0.0 2.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59582.1 - 5.2e-07 30.2 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59582.1 - 3.8e-05 23.5 0.0 8.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59582.1 - 0.00076 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease SAPS PF04499.15 GBG59582.1 - 0.11 11.3 10.7 0.14 10.9 10.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SID-1_RNA_chan PF13965.6 GBG59582.1 - 0.92 7.8 1.7 1.2 7.4 1.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_polI_A34 PF08208.11 GBG59582.1 - 1.7 8.7 49.7 0.021 14.9 30.8 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 RT_RNaseH_2 PF17919.1 GBG59583.1 - 3.2e-31 107.3 0.0 8.1e-31 106.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59583.1 - 4.1e-29 100.9 0.1 9.8e-29 99.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59583.1 - 3.8e-21 74.9 0.4 1.2e-20 73.3 0.4 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59583.1 - 1e-16 61.2 0.1 2.2e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pyr_redox_2 PF07992.14 GBG59583.1 - 2.7e-14 53.1 0.1 7.6e-14 51.6 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase zf-H2C2 PF09337.10 GBG59583.1 - 0.0017 18.6 0.0 0.0067 16.6 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Thioredoxin PF00085.20 GBG59583.1 - 0.0026 17.7 0.0 0.012 15.6 0.0 2.1 1 0 0 1 1 1 1 Thioredoxin rve PF00665.26 GBG59583.1 - 0.0033 17.6 0.0 0.0033 17.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG59583.1 - 0.015 15.5 2.7 4.1 7.8 0.0 3.7 3 0 0 3 3 3 0 Retrotransposon gag protein CLZ PF16526.5 GBG59583.1 - 0.19 12.1 6.6 0.61 10.5 0.6 4.2 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Retrotrans_gag PF03732.17 GBG59584.1 - 0.011 16.1 0.3 0.11 12.8 0.0 2.6 2 1 1 3 3 3 0 Retrotransposon gag protein DUF2781 PF10914.8 GBG59584.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF659 PF04937.15 GBG59585.1 - 4.9e-05 23.2 0.0 9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pyr_redox_2 PF07992.14 GBG59587.1 - 5.7e-30 104.6 0.2 1.4e-29 103.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG59587.1 - 2.8e-16 59.7 0.1 1.2e-11 44.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG59587.1 - 2.3e-11 44.1 2.0 1.2e-08 35.4 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GBG59587.1 - 2.4e-07 30.5 0.3 2.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GBG59587.1 - 1.8e-05 24.0 0.1 0.0076 15.4 0.2 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 GBG59587.1 - 5.9e-05 21.9 0.1 0.005 15.6 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 GBG59587.1 - 9.6e-05 21.7 0.0 0.00033 20.0 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 GBG59587.1 - 0.00013 21.2 0.8 0.00044 19.4 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GBG59587.1 - 0.00016 21.9 0.2 0.0032 17.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG59587.1 - 0.00016 21.4 1.8 0.49 9.9 0.7 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 GBG59587.1 - 0.00021 21.7 0.8 0.24 11.9 0.0 3.7 3 0 0 3 3 3 1 Putative NAD(P)-binding K_oxygenase PF13434.6 GBG59587.1 - 0.013 14.7 0.0 0.089 11.9 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 GBG59587.1 - 0.05 12.4 0.2 0.27 10.1 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase RVP_2 PF08284.11 GBG59588.1 - 1.5e-08 34.5 0.0 3.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG59588.1 - 5.8e-08 32.5 0.1 1.7e-07 31.0 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG59588.1 - 6.6e-07 29.9 0.0 8e-06 26.4 0.0 2.7 3 0 0 3 3 3 1 Aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG59588.1 - 1.6e-05 25.2 0.9 1.6e-05 25.2 0.9 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain gag-asp_proteas PF13975.6 GBG59588.1 - 3.2e-05 24.4 0.0 0.0014 19.1 0.0 3.3 4 0 0 4 4 4 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG59588.1 - 0.044 14.1 1.0 0.23 11.7 0.0 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG59588.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG59588.1 - 0.17 12.2 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RVT_1 PF00078.27 GBG59590.1 - 3e-30 105.4 0.1 5.2e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59590.1 - 1.5e-18 67.0 0.1 3.2e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59590.1 - 1.6e-13 50.5 0.5 4.5e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG59590.1 - 5.4e-11 42.2 0.0 1.3e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG59590.1 - 4.5e-09 36.5 0.0 1.7e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG59590.1 - 1.6e-08 34.4 0.0 3.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG59590.1 - 0.0013 18.9 0.0 0.0033 17.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Dppa2_A PF14049.6 GBG59590.1 - 0.69 10.1 2.9 0.79 9.9 0.4 2.3 3 0 0 3 3 3 0 Dppa2/4 conserved region in higher vertebrates RT_RNaseH_2 PF17919.1 GBG59593.1 - 1.4e-28 98.9 0.0 5e-16 58.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59593.1 - 1.3e-26 92.9 0.0 2.6e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59593.1 - 1e-22 80.8 0.1 1.8e-22 79.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59593.1 - 0.00016 21.7 0.3 0.00036 20.6 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF3824 PF12868.7 GBG59593.1 - 3.7 8.2 11.4 7.7 7.2 11.4 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Retrotrans_gag PF03732.17 GBG59594.1 - 4.8e-05 23.5 0.3 0.00014 22.0 0.3 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein LPP PF04728.13 GBG59594.1 - 0.026 14.9 0.3 0.071 13.5 0.1 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper RT_RNaseH_2 PF17919.1 GBG59595.1 - 2.5e-33 114.1 0.0 5e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59595.1 - 5.8e-30 103.7 0.0 1.1e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59595.1 - 2.5e-26 92.5 0.1 4.9e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59595.1 - 1.3e-19 70.0 0.1 2.8e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59595.1 - 1.7e-14 54.0 0.0 9.6e-14 51.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG59595.1 - 0.035 14.3 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger PRK PF00485.18 GBG59596.1 - 5.7e-05 22.9 0.0 0.001 18.8 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 GBG59596.1 - 0.00015 20.9 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GBG59596.1 - 0.027 14.9 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 GBG59596.1 - 0.082 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 GBG59596.1 - 0.17 12.4 0.0 0.66 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RT_RNaseH_2 PF17919.1 GBG59597.1 - 5.6e-21 74.5 0.0 2.4e-20 72.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59597.1 - 3.4e-11 43.1 0.0 6.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59597.1 - 2e-10 40.9 0.0 1e-09 38.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4175 PF13779.6 GBG59597.1 - 0.28 9.1 2.2 0.41 8.5 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) gag-asp_proteas PF13975.6 GBG59598.1 - 0.0002 21.9 0.0 0.00048 20.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59598.1 - 0.0036 17.9 0.0 0.0085 16.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG59598.1 - 0.0039 17.5 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59598.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG59599.1 - 1.6e-14 54.0 0.1 2.6e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cwf_Cwc_15 PF04889.12 GBG59599.1 - 0.00046 20.0 8.8 0.00046 20.0 8.8 2.9 3 0 0 3 3 3 2 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 GBG59599.1 - 1.9 7.0 18.0 0.29 9.7 9.3 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAP PF02037.27 GBG59601.1 - 0.04 13.7 0.5 0.094 12.5 0.1 1.9 2 0 0 2 2 2 0 SAP domain N6-adenineMlase PF10237.9 GBG59603.1 - 4.5e-39 133.8 1.0 1.4e-38 132.2 0.3 1.9 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 GBG59603.1 - 0.013 15.1 0.2 0.9 9.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical protein 95 DUF4392 PF14336.6 GBG59603.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Aquarius_N PF16399.5 GBG59605.1 - 2.1e-283 942.2 6.5 3.2e-283 941.7 0.0 3.0 2 1 0 2 2 2 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 GBG59605.1 - 8e-27 94.7 0.0 8e-27 94.7 0.0 4.0 3 2 1 4 4 4 1 AAA domain AAA_12 PF13087.6 GBG59605.1 - 7.5e-24 84.5 0.0 7.5e-24 84.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GBG59605.1 - 1.1e-08 35.6 0.9 1.1e-07 32.3 0.4 3.0 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 GBG59605.1 - 0.00055 19.7 0.0 0.0047 16.7 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 GBG59605.1 - 0.0053 17.2 0.0 0.018 15.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 GBG59605.1 - 0.012 15.4 0.3 0.034 14.0 0.3 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 GBG59605.1 - 0.34 11.3 0.0 0.34 11.3 0.0 4.0 4 1 0 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 GBG59605.1 - 0.4 11.0 0.0 0.4 11.0 0.0 3.6 4 0 0 4 4 4 0 AAA domain Borrelia_P83 PF05262.11 GBG59605.1 - 0.67 8.4 24.4 1.3 7.4 24.4 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein MCM PF00493.23 GBG59606.1 - 4.4e-100 333.4 0.0 6.3e-100 332.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GBG59606.1 - 2.5e-31 108.2 0.1 4.2e-31 107.4 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GBG59606.1 - 1.4e-22 79.9 4.2 6e-22 77.9 2.2 2.6 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 GBG59606.1 - 4.7e-19 68.9 0.0 1.5e-18 67.3 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GBG59606.1 - 8e-07 28.6 0.1 6.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GBG59606.1 - 7.8e-06 25.9 0.1 0.00012 22.1 0.0 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GBG59606.1 - 0.0014 18.5 0.1 0.0062 16.4 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-UDP PF14569.6 GBG59606.1 - 0.019 15.1 0.2 0.051 13.7 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Mg_chelatase_C PF13335.6 GBG59606.1 - 0.06 14.0 1.3 0.27 11.9 0.3 2.6 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal NTPase_1 PF03266.15 GBG59606.1 - 0.24 11.3 0.7 21 5.0 0.1 2.4 2 0 0 2 2 2 0 NTPase CDC45 PF02724.14 GBG59607.1 - 0.16 10.2 4.7 0.16 10.2 3.3 1.6 2 0 0 2 2 2 0 CDC45-like protein Integrase_H2C2 PF17921.1 GBG59608.1 - 1.2e-38 131.0 1.3 1.5e-18 66.6 0.2 2.5 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG59608.1 - 2.9e-26 92.0 0.6 2.4e-14 53.6 0.0 3.1 2 1 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG59608.1 - 3.5e-08 33.5 0.0 0.00015 21.9 0.0 2.7 2 0 0 2 2 2 2 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG59608.1 - 3.9e-05 24.1 0.0 0.00013 22.4 0.0 2.0 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease DUF1564 PF07600.11 GBG59608.1 - 0.00056 19.6 0.0 0.0038 16.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) PUF PF00806.19 GBG59608.1 - 0.0016 18.1 0.1 3.9 7.4 0.0 3.3 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat Asp_protease_2 PF13650.6 GBG59608.1 - 0.0019 18.8 0.0 0.0049 17.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 GBG59608.1 - 0.002 17.9 0.2 2 8.2 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain DUF2862 PF11061.8 GBG59608.1 - 0.015 15.1 1.7 0.51 10.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2862) DUF1758 PF05585.12 GBG59608.1 - 0.036 13.9 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG59608.1 - 0.04 13.7 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease S_100 PF01023.19 GBG59608.1 - 0.073 12.8 0.3 12 5.7 0.1 2.8 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain FdsD PF11390.8 GBG59608.1 - 0.11 12.9 1.1 24 5.3 0.0 3.0 3 0 0 3 3 3 0 NADH-dependant formate dehydrogenase delta subunit FdsD RVP_2 PF08284.11 GBG59608.1 - 0.14 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF659 PF04937.15 GBG59610.1 - 3.4e-29 101.7 0.0 7.5e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG59610.1 - 6e-23 81.5 0.1 1.2e-22 80.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59610.1 - 2.9e-18 66.1 0.1 7.5e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59610.1 - 5.1e-10 39.3 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG59610.1 - 1.1e-05 25.1 0.1 3.1e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG59611.1 - 7.1e-32 109.4 0.1 1.7e-31 108.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59611.1 - 3.9e-29 101.8 0.1 7.1e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59611.1 - 1.1e-26 93.1 0.0 2.3e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59611.1 - 6.4e-07 29.9 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59611.1 - 2.5e-05 24.8 0.0 4.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59611.1 - 0.0094 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59611.1 - 0.021 14.6 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG59611.1 - 0.039 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) SeleniumBinding PF11524.8 GBG59612.1 - 0.0067 16.8 7.2 12 6.5 0.1 5.2 1 1 5 6 6 6 1 Selenium binding protein DsrH PF04077.12 GBG59612.1 - 0.0091 16.1 0.0 13 6.0 0.0 4.2 2 2 2 5 5 5 1 DsrH like protein CstA PF02554.14 GBG59612.1 - 0.066 12.1 1.0 4.3 6.1 0.1 2.7 2 1 0 2 2 2 0 Carbon starvation protein CstA Ribosomal_L27A PF00828.19 GBG59612.1 - 0.81 10.4 3.9 46 4.7 0.5 3.4 1 1 1 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Elong-fact-P_C PF09285.11 GBG59612.1 - 9.2 6.1 8.5 1.1e+02 2.7 0.2 4.1 2 2 0 2 2 2 0 Elongation factor P, C-terminal DUF1593 PF07632.11 GBG59613.1 - 0.093 12.2 3.7 0.12 11.7 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) RVP_2 PF08284.11 GBG59614.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease TolA_bind_tri PF16331.5 GBG59614.1 - 0.01 15.9 2.0 0.042 13.9 2.0 2.1 1 0 0 1 1 1 0 TolA binding protein trimerisation SlyX PF04102.12 GBG59614.1 - 0.016 15.8 0.4 0.016 15.8 0.4 3.7 2 1 1 3 3 3 0 SlyX Trimer_CC PF08954.11 GBG59614.1 - 0.024 14.2 0.7 0.07 12.7 0.4 2.0 1 1 0 1 1 1 0 Trimerisation motif CTNNB1_binding PF08347.11 GBG59614.1 - 0.04 14.1 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding TRPM_tetra PF16519.5 GBG59614.1 - 0.21 11.7 1.9 0.78 9.9 0.1 2.6 2 1 1 3 3 3 0 Tetramerisation domain of TRPM MIF4G_like_2 PF09090.11 GBG59614.1 - 3.2 7.1 10.2 2.6 7.4 0.0 2.1 1 1 1 2 2 2 0 MIF4G like Integrase_H2C2 PF17921.1 GBG59615.1 - 1.1e-14 54.3 0.0 2.1e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59615.1 - 0.0063 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG59615.1 - 0.0092 16.2 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Histone PF00125.24 GBG59616.1 - 3.2e-13 50.2 0.2 5.9e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GBG59616.1 - 0.038 14.1 0.3 0.098 12.7 0.1 1.8 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF1547 PF07577.11 GBG59616.1 - 0.047 14.1 0.1 0.55 10.6 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) CENP-S PF15630.6 GBG59616.1 - 0.07 13.5 0.3 0.07 13.5 0.3 2.0 2 0 0 2 2 2 0 CENP-S protein UPF0014 PF03649.13 GBG59617.1 - 1.9e-66 223.9 19.0 2.9e-66 223.3 19.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) RVT_1 PF00078.27 GBG59617.1 - 4.7e-29 101.5 0.2 2.6e-28 99.1 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59617.1 - 4e-23 81.4 0.0 1.6e-22 79.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59617.1 - 1.3e-21 76.9 0.0 6.1e-21 74.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59617.1 - 2.6e-06 27.9 0.0 1.6e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59617.1 - 3.7e-06 27.5 0.0 1.2e-05 25.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59617.1 - 1.7e-05 24.6 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59617.1 - 0.00099 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF4618 PF15397.6 GBG59617.1 - 0.0057 16.1 0.4 0.012 15.0 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Chromo PF00385.24 GBG59618.1 - 0.021 14.7 0.0 0.021 14.7 0.0 3.3 4 0 0 4 4 4 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG59618.1 - 0.074 12.7 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DAO PF01266.24 GBG59619.1 - 1.6e-42 146.4 1.7 1.1e-27 97.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO_C PF16901.5 GBG59619.1 - 2e-34 118.2 0.0 2e-34 118.2 0.0 2.1 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase RVT_1 PF00078.27 GBG59619.1 - 4.7e-23 81.9 0.0 8.3e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59619.1 - 2e-15 56.6 0.0 5.9e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAD_binding_2 PF00890.24 GBG59619.1 - 1.7e-07 30.7 3.0 6.2e-05 22.3 1.1 2.3 2 0 0 2 2 2 2 FAD binding domain RT_RNaseH PF17917.1 GBG59619.1 - 6.1e-07 29.7 0.0 1.8e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59619.1 - 1.1e-06 28.8 0.0 3.8e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain FAD_binding_3 PF01494.19 GBG59619.1 - 3.4e-05 23.3 5.9 0.16 11.2 5.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GBG59619.1 - 6.8e-05 22.2 0.1 0.00013 21.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Tudor-knot PF11717.8 GBG59619.1 - 0.00052 19.8 0.1 0.018 15.0 0.0 2.6 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain GIDA PF01134.22 GBG59619.1 - 0.0023 17.1 0.7 0.033 13.3 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Chromo PF00385.24 GBG59619.1 - 0.013 15.4 0.0 0.045 13.7 0.0 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain HI0933_like PF03486.14 GBG59619.1 - 0.028 13.2 0.2 0.044 12.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 GBG59619.1 - 0.082 13.5 1.2 0.34 11.5 1.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GBG59619.1 - 0.11 11.8 16.6 0.011 15.1 7.8 2.8 3 1 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GBG59619.1 - 0.16 11.1 0.2 0.53 9.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF5523 PF17661.1 GBG59619.1 - 0.99 9.0 7.3 1.8 8.2 7.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF1118 PF06549.12 GBG59620.1 - 7.6e-16 58.5 0.4 1.5e-15 57.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1118) JmjC PF02373.22 GBG59621.1 - 2.3e-17 63.5 0.1 5.4e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 GBG59621.1 - 8.4e-16 58.4 4.3 3.7e-11 43.2 0.2 2.6 3 0 0 3 3 3 2 Cupin-like domain DUF659 PF04937.15 GBG59622.1 - 1.7e-19 70.2 0.0 2.5e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59622.1 - 1.4e-05 24.7 0.1 2.8e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NAC PF01849.18 GBG59624.1 - 5.2e-25 87.2 0.5 1.1e-24 86.1 0.5 1.6 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 GBG59624.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF3110 PF11360.8 GBG59624.1 - 0.28 11.4 3.6 0.79 10.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) DUF4763 PF15960.5 GBG59624.1 - 0.72 9.1 3.2 6.1 6.1 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) PBP1_TM PF14812.6 GBG59624.1 - 4.7 7.6 9.3 2.1 8.8 6.8 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pes-10 PF07149.11 GBG59624.1 - 8.2 5.4 11.4 3.3 6.7 5.0 2.0 2 0 0 2 2 2 0 Pes-10 NAC PF01849.18 GBG59625.1 - 5.1e-25 87.2 0.5 1.1e-24 86.2 0.5 1.6 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 GBG59625.1 - 0.066 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF4763 PF15960.5 GBG59625.1 - 0.2 10.9 2.4 2.1 7.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF3110 PF11360.8 GBG59625.1 - 0.25 11.5 3.6 0.75 10.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) PBP1_TM PF14812.6 GBG59625.1 - 0.96 9.9 10.1 0.32 11.4 7.4 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 GBG59625.1 - 3.6 7.3 12.1 0.22 11.3 5.8 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Mo25 PF08569.11 GBG59626.1 - 1.8e-98 330.0 0.3 2e-98 329.8 0.3 1.0 1 0 0 1 1 1 1 Mo25-like RVT_1 PF00078.27 GBG59627.1 - 1.4e-19 70.5 0.2 1.9e-19 70.1 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG59627.1 - 0.025 14.0 34.2 0.035 13.5 34.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG59627.1 - 1.5 6.9 35.0 2.1 6.4 35.0 1.2 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 GBG59627.1 - 2 6.1 13.2 2.7 5.7 13.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Mpp10 PF04006.12 GBG59627.1 - 3.7 5.9 36.7 5.4 5.3 36.7 1.2 1 0 0 1 1 1 0 Mpp10 protein Lin-8 PF03353.15 GBG59627.1 - 5.9 6.4 19.3 11 5.5 19.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AhpC-TSA_2 PF13911.6 GBG59628.1 - 0.021 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme NIR_SIR PF01077.22 GBG59629.1 - 7.3e-48 162.1 0.0 6.5e-36 123.2 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 GBG59629.1 - 3.1e-35 119.8 0.0 3.8e-16 58.7 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain BUD22 PF09073.10 GBG59630.1 - 0.63 9.3 30.1 1.2 8.4 30.1 1.4 1 0 0 1 1 1 0 BUD22 DUF4683 PF15735.5 GBG59630.1 - 2.6 7.6 9.9 4 7.0 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) CDC45 PF02724.14 GBG59630.1 - 2.7 6.2 20.4 4 5.6 20.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF966 PF06136.13 GBG59630.1 - 4.3 7.0 12.5 7 6.3 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Cwf_Cwc_15 PF04889.12 GBG59630.1 - 9.4 5.9 29.0 2.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 GBG59631.1 - 1.9e-29 101.3 11.9 3.8e-07 30.7 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG59631.1 - 3.3e-08 33.7 1.9 0.0083 16.4 0.1 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG59631.1 - 4.8e-06 25.5 1.4 1.1 7.9 0.1 3.7 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GBG59631.1 - 6.8e-05 22.0 0.7 0.11 11.4 0.2 3.4 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GBG59631.1 - 0.00062 18.6 0.0 0.032 13.0 0.0 2.8 1 1 3 4 4 4 2 Nup133 N terminal like eIF2A PF08662.11 GBG59631.1 - 0.0079 16.1 0.2 1.5 8.7 0.2 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 GBG59631.1 - 0.0087 15.8 0.5 9.7 5.8 0.1 3.7 2 1 1 3 3 3 2 TUP1-like enhancer of split PALB2_WD40 PF16756.5 GBG59631.1 - 0.015 14.2 0.8 0.19 10.6 0.2 2.6 2 2 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 GBG59631.1 - 0.033 12.7 0.2 4.5 5.7 0.0 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain RVT_1 PF00078.27 GBG59633.1 - 7.1e-31 107.4 0.0 1.2e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59633.1 - 5.1e-30 103.5 0.0 2.2e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59633.1 - 7.7e-28 96.9 0.0 1.6e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59633.1 - 2.7e-15 56.2 0.7 9.7e-15 54.4 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG59633.1 - 5.7e-10 39.4 0.2 3.4e-09 36.9 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG59633.1 - 4.8e-05 23.5 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG59634.1 - 0.17 12.0 0.2 0.39 10.9 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle BTB PF00651.31 GBG59635.1 - 1.4e-17 63.9 0.0 3.1e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 GBG59635.1 - 9e-07 29.0 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 SPRY domain RT_RNaseH_2 PF17919.1 GBG59636.1 - 1.1e-30 105.6 0.0 4.1e-15 55.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59636.1 - 1.3e-29 102.5 0.0 2.8e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59636.1 - 1.1e-15 57.5 4.5 1.4e-15 57.1 0.0 3.4 5 0 0 5 5 5 1 Integrase zinc binding domain rve PF00665.26 GBG59636.1 - 1.3e-07 31.8 0.0 9.3e-07 29.1 0.1 2.4 1 1 1 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG59636.1 - 2.4e-07 30.5 0.0 5.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG59636.1 - 3.2e-05 24.1 0.0 7.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG59636.1 - 0.0072 17.0 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease IncFII_repA PF02387.15 GBG59638.1 - 2.6 7.2 9.2 3.7 6.7 9.2 1.1 1 0 0 1 1 1 0 IncFII RepA protein family RT_RNaseH_2 PF17919.1 GBG59639.1 - 2.3e-24 85.3 0.0 5.6e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59639.1 - 6.1e-23 81.1 0.1 2.5e-22 79.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59639.1 - 1.4e-19 70.5 0.1 3e-19 69.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59639.1 - 2.6e-16 59.5 1.1 8.6e-16 57.8 0.3 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG59639.1 - 1.6e-11 44.4 0.0 6.2e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG59639.1 - 0.0011 19.1 0.2 0.003 17.7 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG59639.1 - 0.0023 18.2 3.5 0.0031 17.7 0.6 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein CENP-K PF11802.8 GBG59639.1 - 0.031 13.9 4.1 0.065 12.8 4.1 1.4 1 0 0 1 1 1 0 Centromere-associated protein K GvpG PF05120.12 GBG59639.1 - 0.057 13.4 0.6 0.15 12.1 0.6 1.7 1 0 0 1 1 1 0 Gas vesicle protein G AIP3 PF03915.13 GBG59639.1 - 0.36 9.9 4.5 0.64 9.0 4.5 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 DUF3499 PF12005.8 GBG59639.1 - 0.79 10.3 9.9 0.6 10.7 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Integrase_H2C2 PF17921.1 GBG59640.1 - 1e-16 60.7 0.0 2.2e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59640.1 - 3.7e-15 56.2 0.0 8.7e-14 51.7 0.0 3.1 3 0 0 3 3 3 1 Integrase core domain Dynactin_p22 PF07426.11 GBG59640.1 - 0.22 11.4 1.7 4.5 7.1 0.1 3.0 3 0 0 3 3 3 0 Dynactin subunit p22 SlyX PF04102.12 GBG59640.1 - 0.25 12.0 1.3 1.6 9.4 0.0 2.8 3 0 0 3 3 3 0 SlyX Exo_endo_phos PF03372.23 GBG59641.1 - 1.3e-07 31.4 0.2 2.3e-07 30.6 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG59641.1 - 0.0027 17.5 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase CobW_C PF07683.14 GBG59641.1 - 0.026 14.4 0.9 1.7 8.6 0.1 3.0 3 0 0 3 3 3 0 Cobalamin synthesis protein cobW C-terminal domain Ion_trans_N PF08412.10 GBG59641.1 - 0.086 12.5 0.2 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Ion transport protein N-terminal Band_7 PF01145.25 GBG59642.1 - 2.1e-23 83.2 0.0 2.9e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Myb_DNA-bind_4 PF13837.6 GBG59643.1 - 6.5e-06 26.4 0.3 1.1e-05 25.8 0.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG59643.1 - 0.0011 18.9 0.5 0.002 18.2 0.5 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG59643.1 - 0.016 15.5 0.1 0.028 14.7 0.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RT_RNaseH_2 PF17919.1 GBG59644.1 - 6.1e-34 116.0 0.0 1.3e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59644.1 - 4.4e-30 104.1 0.1 9.4e-30 103.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59644.1 - 2.4e-28 98.7 0.1 1.5e-13 50.9 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG59644.1 - 2.9e-19 69.5 0.3 7.6e-19 68.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59644.1 - 2.5e-15 56.3 0.1 6.8e-15 54.9 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG59644.1 - 0.0079 16.0 0.3 3 7.7 0.0 3.2 2 0 0 2 2 2 1 Integrase core domain DUF1564 PF07600.11 GBG59644.1 - 0.019 14.6 0.0 0.077 12.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG59644.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG59645.1 - 3.1e-60 200.4 0.0 1e-28 99.3 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59645.1 - 2.5e-54 182.0 0.4 2.2e-28 98.6 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59645.1 - 8.2e-47 159.6 0.8 4.2e-27 95.1 0.5 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG59645.1 - 7.3e-09 35.8 8.2 3.6e-05 24.0 0.3 5.2 4 0 0 4 4 4 2 Retrotransposon gag protein NPV_P10 PF05531.12 GBG59645.1 - 3.6 8.1 8.4 20 5.7 0.1 4.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 GBG59646.1 - 0.17 12.5 3.3 1.2 9.8 0.1 2.9 2 1 0 2 2 2 0 SlyX MscS_porin PF12795.7 GBG59646.1 - 3.2 7.2 8.1 1.2 8.7 4.8 1.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain SlyX PF04102.12 GBG59647.1 - 0.027 15.1 2.5 0.2 12.3 0.2 3.2 2 0 0 2 2 2 0 SlyX PTS_IIA PF02255.16 GBG59647.1 - 0.43 10.7 6.2 1.5 8.9 6.2 1.9 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit FoP_duplication PF13865.6 GBG59649.1 - 1.4e-12 48.0 12.0 1.4e-12 48.0 12.0 6.3 4 2 3 7 7 7 1 C-terminal duplication domain of Friend of PRMT1 RT_RNaseH_2 PF17919.1 GBG59650.1 - 5.7e-31 106.5 0.1 1.1e-30 105.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59650.1 - 1.9e-28 98.8 0.3 4.6e-28 97.6 0.3 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59650.1 - 1.4e-12 47.6 0.0 4.5e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MSP1a PF11670.8 GBG59650.1 - 0.3 10.3 0.1 0.3 10.3 0.1 1.5 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) Noelin-1 PF12308.8 GBG59650.1 - 0.51 10.4 3.2 0.5 10.4 0.9 2.2 2 0 0 2 2 2 0 Neurogenesis glycoprotein Aminotran_3 PF00202.21 GBG59651.1 - 1.7e-57 195.0 0.1 2.4e-57 194.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GBG59651.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II RVT_1 PF00078.27 GBG59652.1 - 2.7e-28 99.0 0.1 4.6e-28 98.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59652.1 - 7.5e-19 67.6 0.0 3e-14 52.8 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59652.1 - 1.6e-08 34.8 0.0 4.4e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59654.1 - 1.5e-06 27.9 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-B_dimeris PF09026.10 GBG59654.1 - 2 8.9 4.5 11 6.5 4.5 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RE_BstXI PF09552.10 GBG59657.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 BstXI restriction endonuclease Ins134_P3_kin_N PF17927.1 GBG59657.1 - 0.022 15.2 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain ChW PF07538.11 GBG59658.1 - 0.42 10.6 0.1 0.42 10.6 0.1 2.1 2 0 0 2 2 2 0 Clostridial hydrophobic W DUF4191 PF13829.6 GBG59659.1 - 0.00072 19.0 10.6 0.0011 18.4 10.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) FA_desaturase PF00487.24 GBG59659.1 - 0.093 12.5 0.5 0.12 12.2 0.5 1.2 1 0 0 1 1 1 0 Fatty acid desaturase TraG_N PF07916.11 GBG59659.1 - 0.13 11.1 14.7 0.18 10.6 14.7 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF3043 PF11241.8 GBG59659.1 - 0.28 11.2 17.5 0.47 10.5 17.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Pex24p PF06398.11 GBG59659.1 - 3.5 6.5 6.1 4.8 6.1 6.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF2207 PF09972.9 GBG59659.1 - 6.7 5.3 7.1 8.8 5.0 7.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PRIMA1 PF16101.5 GBG59660.1 - 2 8.5 4.0 3.9 7.5 4.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RVT_1 PF00078.27 GBG59661.1 - 3.3e-36 124.9 0.1 5.3e-36 124.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59661.1 - 9.6e-30 103.0 0.0 2.5e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59661.1 - 1.7e-28 98.5 0.0 6.1e-28 96.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59661.1 - 1.1e-06 28.4 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59661.1 - 2.1e-06 28.3 0.0 4.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59661.1 - 0.00055 20.4 0.1 0.0028 18.2 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG59661.1 - 0.0079 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG59661.1 - 0.008 16.0 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease SDA1 PF05285.12 GBG59661.1 - 0.4 10.1 46.5 0.71 9.2 46.5 1.3 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG59662.1 - 1.1e-20 74.1 0.0 1.9e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59662.1 - 7e-18 64.5 0.0 1.1e-13 51.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59662.1 - 1.3e-08 35.0 0.0 4.2e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG59662.1 - 3.3e-07 30.5 0.0 8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG59662.1 - 0.018 15.7 0.0 0.035 14.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG59664.1 - 0.00049 20.6 0.1 0.0011 19.5 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG59664.1 - 0.018 14.8 0.1 0.034 13.9 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG59664.1 - 0.03 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59664.1 - 0.1 13.3 0.1 0.22 12.2 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG59665.1 - 3.7e-28 98.3 0.1 8e-28 97.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59665.1 - 4.1e-05 23.3 0.6 0.00012 21.8 0.3 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Fasciclin PF02469.22 GBG59666.1 - 1.7e-22 80.0 0.0 2.1e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 GBG59667.1 - 5.7e-17 62.1 0.1 7.4e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain RVT_1 PF00078.27 GBG59668.1 - 3.1e-29 102.1 0.0 4.2e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG59668.1 - 0.08 12.9 0.1 4.9 7.2 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L34 Fasciclin PF02469.22 GBG59669.1 - 2.9e-19 69.5 0.0 3.5e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain RT_RNaseH_2 PF17919.1 GBG59670.1 - 2.3e-24 85.3 0.0 4.8e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59670.1 - 5.1e-22 78.1 0.0 1.3e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59670.1 - 1.4e-16 60.4 0.1 4.1e-16 58.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain CcmE PF03100.15 GBG59670.1 - 6e-15 55.4 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 CcmE RVT_1 PF00078.27 GBG59670.1 - 1.5e-11 44.2 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG59670.1 - 3.6e-06 27.2 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG59670.1 - 0.00095 18.9 0.0 0.1 12.4 0.0 2.4 1 1 1 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59670.1 - 0.02 15.5 0.0 0.071 13.8 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG59670.1 - 0.025 15.1 0.0 0.11 13.1 0.0 2.1 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Seryl_tRNA_N PF02403.22 GBG59670.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.12 GBG59670.1 - 0.095 12.7 6.0 0.26 11.3 6.0 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Asp_protease PF09668.10 GBG59670.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG59672.1 - 7.4e-58 193.3 1.2 1.1e-28 99.6 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59672.1 - 4.9e-56 186.9 0.1 9.7e-33 112.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59672.1 - 1.3e-16 60.4 0.1 3.9e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain CcmE PF03100.15 GBG59672.1 - 3.2e-13 49.8 0.0 6.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 CcmE RVT_1 PF00078.27 GBG59672.1 - 3.4e-10 39.8 0.0 7.7e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG59672.1 - 0.00096 19.3 0.0 0.003 17.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DUF2862 PF11061.8 GBG59672.1 - 0.0017 18.2 0.6 0.54 10.1 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2862) NAAA-beta PF15508.6 GBG59672.1 - 0.021 15.1 0.1 7.9 6.9 0.0 2.7 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Mcp5_PH PF12814.7 GBG59672.1 - 1.1 9.4 4.7 2.2 8.4 0.3 2.5 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Fasciclin PF02469.22 GBG59673.1 - 7.4e-15 55.3 0.0 9.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain DUF2964 PF11177.8 GBG59673.1 - 0.074 13.3 1.9 0.25 11.6 1.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) DEC-1_N PF04625.13 GBG59673.1 - 0.099 11.6 2.4 0.11 11.4 2.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CAP_N PF01213.19 GBG59673.1 - 1.7 8.1 5.3 2.3 7.6 5.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG59673.1 - 2 8.5 7.8 0.17 11.9 2.7 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SRP-alpha_N PF04086.13 GBG59674.1 - 7.4 6.4 9.2 10 5.9 9.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Fasciclin PF02469.22 GBG59676.1 - 2.2e-12 47.3 0.0 2.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain DUF1290 PF06947.12 GBG59676.1 - 0.028 14.5 0.1 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) Csa1 PF06023.12 GBG59676.1 - 0.18 11.1 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Histone PF00125.24 GBG59677.1 - 3.3e-11 43.6 0.1 7.5e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Fasciclin PF02469.22 GBG59680.1 - 7.1e-16 58.6 0.0 8.8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain DEC-1_N PF04625.13 GBG59680.1 - 0.11 11.5 2.1 0.11 11.5 2.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF2964 PF11177.8 GBG59680.1 - 0.13 12.5 2.4 0.39 11.0 2.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) CAP_N PF01213.19 GBG59680.1 - 0.95 8.9 4.6 1.3 8.5 4.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG59680.1 - 7.6 6.6 8.9 1.1 9.3 4.8 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RT_RNaseH_2 PF17919.1 GBG59681.1 - 5.4e-30 103.4 0.0 4.7e-15 55.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59681.1 - 7.7e-29 100.1 0.0 1.9e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59681.1 - 6.7e-27 94.5 0.1 1.4e-26 93.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59681.1 - 7.3e-14 51.6 1.0 2.1e-13 50.1 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG59681.1 - 6e-12 45.8 0.2 4.9e-11 42.9 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG59681.1 - 2e-05 24.7 0.0 5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG59682.1 - 3.7e-05 24.2 0.0 0.0001 22.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59682.1 - 0.00039 21.0 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG59682.1 - 0.00095 19.0 0.1 0.0026 17.6 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG59682.1 - 0.00097 18.7 0.0 0.0031 17.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 GBG59682.1 - 0.0024 18.1 0.0 0.0061 16.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Rx_N PF18052.1 GBG59682.1 - 0.11 12.8 0.1 16 5.9 0.0 3.1 3 0 0 3 3 3 0 Rx N-terminal domain zf-CCHC PF00098.23 GBG59682.1 - 0.22 11.7 1.6 0.38 10.9 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG59682.1 - 0.52 10.2 6.2 0.06 13.2 2.0 1.6 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG59684.1 - 3.2e-54 183.8 0.4 2e-26 92.9 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59684.1 - 8.5e-53 176.6 0.2 5.7e-31 106.5 0.1 3.6 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59684.1 - 4.1e-31 107.4 0.0 5e-20 71.7 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59684.1 - 3.1e-14 52.8 0.1 6.7e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG59684.1 - 8.7e-05 22.7 0.0 0.0003 20.9 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG59684.1 - 0.025 15.2 0.0 0.071 13.8 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Epimerase PF01370.21 GBG59685.1 - 5.2e-46 157.1 0.0 6.1e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GBG59685.1 - 2.6e-43 148.7 0.0 3.7e-41 141.6 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GBG59685.1 - 1.4e-12 47.4 0.0 2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 GBG59685.1 - 7.4e-11 41.6 0.0 9.9e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GBG59685.1 - 8.5e-08 31.7 0.1 9.4e-07 28.3 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GBG59685.1 - 3.6e-05 23.1 0.1 0.00044 19.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 GBG59685.1 - 0.00037 20.0 0.7 0.0016 17.9 0.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 GBG59685.1 - 0.00062 19.4 0.1 0.001 18.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 GBG59685.1 - 0.0044 17.0 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 KR domain Drf_FH1 PF06346.12 GBG59686.1 - 0.008 15.9 5.0 0.013 15.2 4.9 1.5 1 1 0 1 1 1 1 Formin Homology Region 1 Sugarporin_N PF11471.8 GBG59687.1 - 4.5 7.3 6.1 1.4 9.0 1.5 2.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension RT_RNaseH PF17917.1 GBG59688.1 - 8.5e-22 77.4 0.0 1.7e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59688.1 - 1e-21 76.8 0.0 2.4e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59688.1 - 1.4e-07 32.0 0.1 5.3e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59688.1 - 0.00058 20.5 0.0 0.0017 19.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG59688.1 - 0.069 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG59688.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease RBM1CTR PF08081.11 GBG59688.1 - 5.6 7.1 7.5 9.5 6.4 2.9 2.7 1 1 1 2 2 2 0 RBM1CTR (NUC064) family AAA PF00004.29 GBG59689.1 - 1.1e-36 126.2 0.0 1.7e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG59689.1 - 5.3e-11 42.2 0.0 1.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GBG59689.1 - 1.2e-05 25.1 0.0 2.4e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GBG59689.1 - 2e-05 24.6 0.3 0.00034 20.6 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 GBG59689.1 - 5e-05 23.3 0.0 8.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_16 PF13191.6 GBG59689.1 - 0.00012 22.5 0.5 0.00092 19.6 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 GBG59689.1 - 0.00012 21.3 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) MCM PF00493.23 GBG59689.1 - 0.00014 21.0 0.0 0.00066 18.8 0.0 1.9 1 1 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 GBG59689.1 - 0.0004 20.7 0.1 0.012 15.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GBG59689.1 - 0.00041 20.1 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 GBG59689.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GBG59689.1 - 0.0019 18.8 0.0 0.0036 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GBG59689.1 - 0.0024 18.0 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GBG59689.1 - 0.0036 17.0 0.0 0.015 15.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 GBG59689.1 - 0.006 16.1 0.0 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 GBG59689.1 - 0.0063 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 GBG59689.1 - 0.0075 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 GBG59689.1 - 0.0083 15.7 0.3 0.25 10.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GBG59689.1 - 0.0085 15.5 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GBG59689.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GBG59689.1 - 0.016 14.9 0.2 0.032 14.0 0.2 1.4 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 GBG59689.1 - 0.036 13.5 0.0 7.2 6.0 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 GBG59689.1 - 0.038 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein CPT PF07931.12 GBG59689.1 - 0.047 13.5 0.4 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 GBG59689.1 - 0.047 13.6 0.1 0.44 10.4 0.0 2.3 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 GBG59689.1 - 0.066 12.6 0.1 0.22 10.8 0.1 1.9 1 1 0 1 1 1 0 KaiC AAA_2 PF07724.14 GBG59689.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 GBG59689.1 - 0.087 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 GBG59689.1 - 0.09 12.6 0.0 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 GBG59689.1 - 0.091 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GBG59689.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 GBG59689.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 GBG59689.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GBG59689.1 - 0.16 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SelK_SelG PF10961.8 GBG59689.1 - 5.7 7.6 12.2 15 6.3 12.2 1.7 1 0 0 1 1 1 0 Selenoprotein SelK_SelG ubiquitin PF00240.23 GBG59691.1 - 1.3e-21 76.1 0.1 2.5e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GBG59691.1 - 3.5e-12 46.0 0.1 5.8e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 GBG59691.1 - 5.6e-07 29.4 39.4 0.04 13.9 6.3 4.9 2 2 3 5 5 5 5 STI1 domain Ubiquitin_4 PF18036.1 GBG59691.1 - 0.0046 17.0 0.1 0.45 10.6 0.0 2.2 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 GBG59691.1 - 0.0074 16.7 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GBG59691.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 GBG59691.1 - 0.11 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GBG59691.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RPN13_C PF16550.5 GBG59691.1 - 0.18 12.0 14.1 0.91 9.7 6.8 2.9 2 2 0 2 2 2 0 UCH-binding domain Elf4 PF07011.11 GBG59691.1 - 0.2 11.6 0.5 0.41 10.6 0.5 1.5 1 0 0 1 1 1 0 Early Flowering 4 domain L27 PF02828.16 GBG59691.1 - 0.29 10.9 1.6 13 5.7 0.1 4.1 5 1 1 6 6 6 0 L27 domain MLTR_LBD PF17765.1 GBG59691.1 - 0.31 11.2 3.0 5.9 7.0 0.2 2.7 2 1 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain GerD PF17898.1 GBG59691.1 - 0.77 9.7 20.0 0.66 9.9 6.3 3.9 2 2 0 2 2 2 0 Spore germination GerD central core domain ubiquitin PF00240.23 GBG59692.1 - 1.4e-21 76.1 0.1 2.4e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GBG59692.1 - 3.4e-12 46.0 0.1 5.7e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 GBG59692.1 - 5.7e-07 29.4 37.9 0.12 12.3 8.1 4.9 2 2 3 5 5 5 5 STI1 domain Ubiquitin_4 PF18036.1 GBG59692.1 - 0.0046 17.0 0.1 0.45 10.6 0.0 2.2 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 GBG59692.1 - 0.0072 16.8 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain RPN13_C PF16550.5 GBG59692.1 - 0.035 14.3 13.2 0.13 12.4 5.7 2.9 2 2 0 2 2 2 0 UCH-binding domain TBK1_ULD PF18396.1 GBG59692.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 GBG59692.1 - 0.11 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GBG59692.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Elf4 PF07011.11 GBG59692.1 - 0.2 11.6 0.5 0.41 10.6 0.5 1.4 1 0 0 1 1 1 0 Early Flowering 4 domain MLTR_LBD PF17765.1 GBG59692.1 - 0.27 11.4 2.9 5.6 7.0 0.2 2.7 2 1 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain GerD PF17898.1 GBG59692.1 - 0.37 10.7 18.3 0.23 11.4 4.6 3.7 2 1 0 2 2 2 0 Spore germination GerD central core domain L27 PF02828.16 GBG59692.1 - 0.5 10.2 2.4 12 5.7 0.1 4.1 5 1 1 6 6 6 0 L27 domain XPC-binding PF09280.11 GBG59692.1 - 2.1 8.1 35.7 0.15 11.8 0.3 5.6 3 3 2 5 5 5 0 XPC-binding domain RT_RNaseH_2 PF17919.1 GBG59694.1 - 1.6e-47 159.6 0.0 5.7e-25 87.3 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59694.1 - 1.7e-36 124.7 0.0 1.7e-18 66.8 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG59694.1 - 6.4e-07 29.9 0.0 1.4e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59694.1 - 8.5e-07 29.5 0.0 3.2e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59694.1 - 7.7e-06 25.7 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59694.1 - 0.0031 17.3 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG59694.1 - 0.0046 16.8 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Rz1 PF06085.11 GBG59694.1 - 0.046 13.5 2.2 0.1 12.3 2.2 1.6 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor FAM76 PF16046.5 GBG59695.1 - 0.28 10.5 3.6 0.44 9.9 3.6 1.2 1 0 0 1 1 1 0 FAM76 protein GAS PF13851.6 GBG59695.1 - 0.54 9.6 8.9 0.91 8.8 6.0 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4168 PF13767.6 GBG59695.1 - 1.3 10.2 5.0 5 8.4 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4168) Alb1 PF09135.11 GBG59695.1 - 8.6 7.3 12.1 29 5.6 10.2 2.5 2 1 0 2 2 2 0 Alb1 RT_RNaseH_2 PF17919.1 GBG59696.1 - 1.2e-29 102.2 0.0 2.5e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59696.1 - 3e-27 95.0 0.0 7e-27 93.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59696.1 - 4.7e-16 58.6 0.0 1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59696.1 - 2e-13 50.6 0.0 4.1e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG59696.1 - 0.0047 17.1 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Rhamno_transf PF11316.8 GBG59696.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase gag-asp_proteas PF13975.6 GBG59696.1 - 0.035 14.7 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59696.1 - 0.078 13.6 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease GSHPx PF00255.19 GBG59696.1 - 0.084 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase rve_3 PF13683.6 GBG59696.1 - 0.12 12.2 0.0 0.4 10.5 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain gag_pre-integrs PF13976.6 GBG59696.1 - 0.14 12.0 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 GAG-pre-integrase domain NUDE_C PF04880.13 GBG59697.1 - 0.049 14.1 1.2 0.049 14.1 1.2 2.4 3 0 0 3 3 3 0 NUDE protein, C-terminal conserved region DUF148 PF02520.17 GBG59697.1 - 0.23 11.6 2.4 0.72 10.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 MSP1_C PF07462.11 GBG59697.1 - 0.6 8.8 6.7 0.044 12.5 1.1 1.8 1 1 1 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus GCN5L1 PF06320.13 GBG59697.1 - 0.64 10.2 6.8 0.56 10.4 5.0 1.7 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF659 PF04937.15 GBG59698.1 - 1e-28 100.1 0.0 2.2e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SDA1 PF05285.12 GBG59698.1 - 0.82 9.0 23.6 1.1 8.6 23.6 1.2 1 0 0 1 1 1 0 SDA1 RNA_pol_3_Rpc31 PF11705.8 GBG59699.1 - 1.4 9.1 14.5 2.1 8.6 14.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 HABP4_PAI-RBP1 PF04774.15 GBG59699.1 - 1.5 9.7 18.8 3 8.7 18.8 1.5 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family rve PF00665.26 GBG59700.1 - 2.9e-08 33.9 0.4 7.7e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG59700.1 - 0.091 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain RVT_1 PF00078.27 GBG59701.1 - 1.5e-32 113.0 0.0 2.6e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59701.1 - 2.5e-31 107.6 0.0 6.9e-31 106.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59701.1 - 8.8e-30 103.1 0.1 1.8e-29 102.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Metal_CEHH PF14455.6 GBG59701.1 - 0.09 12.4 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Predicted metal binding domain Phage_GPO PF05929.11 GBG59701.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF659 PF04937.15 GBG59702.1 - 5.3e-17 62.1 0.4 9.8e-17 61.2 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59702.1 - 1.6e-07 31.0 0.2 3.5e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG59703.1 - 2.6e-56 190.6 0.4 3.1e-28 98.8 0.1 2.9 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) SWIB PF02201.18 GBG59703.1 - 1.7e-20 72.7 0.3 3.8e-20 71.5 0.3 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain RT_RNaseH PF17917.1 GBG59703.1 - 3.6e-14 52.9 0.7 3e-13 49.9 0.2 2.8 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59703.1 - 9.3e-11 41.7 0.0 9.5e-06 25.6 0.0 3.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Plus-3 PF03126.18 GBG59703.1 - 7.2e-07 29.7 0.0 2.5e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Plus-3 domain C5HCH PF17982.1 GBG59703.1 - 6.7e-06 26.2 5.2 1.6e-05 25.0 5.2 1.6 1 0 0 1 1 1 1 NSD Cys-His rich domain Chromo PF00385.24 GBG59703.1 - 0.0025 17.7 0.0 0.0059 16.5 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG59703.1 - 0.015 15.6 2.6 0.81 10.0 0.0 3.9 3 0 0 3 3 3 0 Retrotransposon gag protein zf-HIT PF04438.16 GBG59703.1 - 0.05 13.5 8.7 0.11 12.3 8.7 1.6 1 0 0 1 1 1 0 HIT zinc finger TMEM247 PF15444.6 GBG59703.1 - 2.1 8.3 6.4 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 Transmembrane protein 247 FokI_N PF02981.15 GBG59705.1 - 0.14 12.3 1.5 0.94 9.6 0.7 2.4 2 1 0 2 2 2 0 Restriction endonuclease FokI, recognition domain RVT_1 PF00078.27 GBG59707.1 - 7e-58 195.7 0.8 4.5e-26 91.7 0.0 3.9 4 0 0 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59707.1 - 1.4e-57 191.9 0.0 2.4e-22 78.8 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59707.1 - 1.2e-53 179.8 0.0 1.2e-21 77.0 0.1 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59707.1 - 2.4e-48 162.1 6.4 2e-18 66.2 0.2 3.6 3 0 0 3 3 3 3 Integrase zinc binding domain RVP_2 PF08284.11 GBG59707.1 - 2e-07 30.9 0.0 4.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Plus-3 PF03126.18 GBG59707.1 - 2.8e-07 31.0 0.1 1.2e-06 29.0 0.1 2.1 2 0 0 2 2 2 1 Plus-3 domain BLOC1_2 PF10046.9 GBG59707.1 - 0.00064 20.0 4.8 0.23 11.8 3.6 4.9 4 0 0 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Retrotrans_gag PF03732.17 GBG59707.1 - 0.0059 16.9 0.2 0.0059 16.9 0.2 5.2 5 0 0 5 5 5 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG59707.1 - 0.0094 16.2 0.0 0.74 10.1 0.0 3.2 3 0 0 3 3 3 1 H2C2 zinc finger DUF4399 PF14347.6 GBG59707.1 - 0.074 13.4 0.0 13 6.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4399) PUF PF00806.19 GBG59707.1 - 0.19 11.5 0.5 17 5.3 0.0 2.8 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat DUF659 PF04937.15 GBG59708.1 - 9.1e-28 97.0 0.0 2.3e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GYF PF02213.16 GBG59709.1 - 3.3e-11 42.7 0.2 3.3e-11 42.7 0.2 1.8 2 0 0 2 2 1 1 GYF domain zf_CCCH_4 PF18345.1 GBG59709.1 - 1.7e-05 24.7 1.3 3.8e-05 23.6 1.3 1.7 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 GBG59709.1 - 0.00026 21.7 0.0 0.0008 20.1 0.0 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 GBG59709.1 - 0.0004 20.1 1.2 0.00072 19.3 1.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger GYF_2 PF14237.6 GBG59709.1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 2.2 3 0 0 3 3 1 1 GYF domain 2 Mpp10 PF04006.12 GBG59709.1 - 0.03 12.8 32.6 0.048 12.1 32.6 1.2 1 0 0 1 1 1 0 Mpp10 protein zf-CCCH PF00642.24 GBG59709.1 - 0.048 13.6 0.8 0.092 12.7 0.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GET2 PF08690.10 GBG59709.1 - 0.057 13.1 11.3 0.088 12.5 11.3 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 zf-CCCH_2 PF14608.6 GBG59709.1 - 0.085 13.4 2.5 0.21 12.1 2.5 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Nop14 PF04147.12 GBG59709.1 - 0.097 10.9 35.9 0.14 10.3 35.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG59709.1 - 0.24 9.6 28.3 0.45 8.8 28.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 GBG59709.1 - 0.27 10.0 20.6 0.4 9.4 20.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIIAH PF12685.7 GBG59709.1 - 0.31 10.8 14.1 0.49 10.2 14.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein PI3K_1B_p101 PF10486.9 GBG59709.1 - 0.36 8.6 10.3 0.52 8.0 10.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RNA_pol_Rpc4 PF05132.14 GBG59709.1 - 0.38 11.2 11.6 0.86 10.0 11.6 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sec62 PF03839.16 GBG59709.1 - 0.56 9.7 7.8 0.92 9.0 7.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 SpoIIP PF07454.11 GBG59709.1 - 0.65 9.4 14.9 0.97 8.8 14.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RRN3 PF05327.11 GBG59709.1 - 0.7 8.4 26.4 1 7.8 26.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDHD PF02862.17 GBG59709.1 - 0.82 9.8 2.9 1.3 9.1 2.9 1.2 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 GBG59709.1 - 0.83 8.6 11.3 1.2 8.0 11.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 GBG59709.1 - 1.2 8.9 23.6 2.1 8.1 23.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 GBG59709.1 - 1.3 8.5 30.1 2.5 7.6 30.1 1.4 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 GBG59709.1 - 1.5 7.5 13.7 2.1 7.0 13.7 1.1 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 GBG59709.1 - 1.7 7.1 10.3 2.3 6.7 10.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DNA_pol_phi PF04931.13 GBG59709.1 - 2.3 6.2 47.2 3.2 5.7 47.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.10 GBG59709.1 - 2.6 8.4 20.5 4.6 7.5 20.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SID-1_RNA_chan PF13965.6 GBG59709.1 - 2.8 6.3 2.8 3.8 5.8 2.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Connexin PF00029.19 GBG59709.1 - 5.2 6.7 12.8 8.5 6.1 12.8 1.2 1 0 0 1 1 1 0 Connexin TRAP_alpha PF03896.16 GBG59709.1 - 6.8 5.8 20.0 13 4.9 20.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Neur_chan_memb PF02932.16 GBG59709.1 - 7 6.6 4.9 10 6.1 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp_protease PF09668.10 GBG59711.1 - 0.011 15.6 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG59711.1 - 0.012 16.2 0.1 0.027 15.1 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG59711.1 - 0.02 14.7 0.0 0.052 13.3 0.0 1.6 2 0 0 2 2 2 0 Retroviral aspartyl protease Noelin-1 PF12308.8 GBG59712.1 - 3.7 7.6 8.9 0.29 11.1 0.7 2.8 2 1 0 2 2 2 0 Neurogenesis glycoprotein Cob_adeno_trans PF01923.18 GBG59712.1 - 7.1 6.7 13.6 42 4.2 0.0 2.6 1 1 0 2 2 2 0 Cobalamin adenosyltransferase WG_beta_rep PF14903.6 GBG59713.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 WG containing repeat Presenilin PF01080.17 GBG59714.1 - 0.11 11.3 4.6 0.11 11.2 4.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4366 PF14283.6 GBG59714.1 - 0.2 11.7 1.3 0.31 11.1 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Peptidase_S49_N PF08496.10 GBG59714.1 - 3.8 7.6 11.4 9.6 6.2 11.4 1.7 1 1 0 1 1 1 0 Peptidase family S49 N-terminal YqhG PF11079.8 GBG59714.1 - 3.9 6.4 6.1 5.1 6.0 6.1 1.1 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function zf-C3HC4_3 PF13920.6 GBG59715.1 - 2.8e-09 36.7 7.2 4.4e-09 36.1 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG59715.1 - 3e-08 33.4 7.9 5e-08 32.7 7.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GBG59715.1 - 1.1e-07 32.0 10.0 1.1e-07 32.0 10.0 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG59715.1 - 1.7e-05 24.6 9.0 3e-05 23.8 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG59715.1 - 4.3e-05 23.3 9.1 9e-05 22.2 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG59715.1 - 0.00019 21.3 8.1 0.00041 20.3 8.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GBG59715.1 - 0.0012 19.1 7.7 0.0014 18.9 6.3 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GBG59715.1 - 0.0022 18.0 4.8 0.0022 18.0 4.8 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 GBG59715.1 - 0.03 14.4 3.9 0.059 13.5 3.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 GBG59715.1 - 0.064 13.1 7.0 0.13 12.1 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 GBG59715.1 - 0.064 13.5 4.3 0.13 12.5 4.3 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain LmjF365940-deam PF14421.6 GBG59715.1 - 0.097 12.3 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases DUF4533 PF15047.6 GBG59715.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) zf-RING_14 PF17978.1 GBG59715.1 - 0.13 12.7 2.3 0.3 11.5 2.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GBG59715.1 - 0.86 9.8 6.6 1.8 8.8 6.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 GBG59715.1 - 1.2 8.8 8.0 0.97 9.1 6.3 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GBG59715.1 - 2.2 8.4 7.5 5 7.2 6.3 2.1 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Integrase_H2C2 PF17921.1 GBG59716.1 - 2.9e-15 56.1 0.1 5.8e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59716.1 - 3.9e-11 43.2 0.3 4.9e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG59716.1 - 0.0001 22.4 0.1 0.00025 21.2 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF659 PF04937.15 GBG59717.1 - 9.3e-31 106.7 0.1 2.6e-30 105.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG59717.1 - 1.1e-10 41.4 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG59717.1 - 1.3e-06 28.9 0.0 6e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59717.1 - 3.6e-05 24.2 0.0 0.00011 22.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG59718.1 - 0.04 14.0 1.9 0.083 13.0 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle CENP_C_N PF15622.6 GBG59718.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal TPX2 PF06886.11 GBG59719.1 - 7.2e-13 48.6 12.2 2.8e-12 46.7 12.2 2.1 1 0 0 1 1 1 1 Targeting protein for Xklp2 (TPX2) TPX2 PF06886.11 GBG59720.1 - 7e-13 48.6 12.2 2.7e-12 46.7 12.2 2.1 1 0 0 1 1 1 1 Targeting protein for Xklp2 (TPX2) TPX2 PF06886.11 GBG59721.1 - 6.9e-13 48.6 12.2 2.7e-12 46.7 12.2 2.1 1 0 0 1 1 1 1 Targeting protein for Xklp2 (TPX2) DUF659 PF04937.15 GBG59722.1 - 4e-28 98.2 0.0 9.1e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) DUF1664 PF07889.12 GBG59723.1 - 0.0043 17.1 1.9 0.0043 17.1 1.9 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) zf-CCHC_5 PF14787.6 GBG59723.1 - 0.019 14.7 3.5 0.047 13.4 3.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger USP8_interact PF08941.10 GBG59723.1 - 0.036 13.9 1.1 0.1 12.4 1.1 1.7 1 0 0 1 1 1 0 USP8 interacting TPR_MLP1_2 PF07926.12 GBG59724.1 - 0.00012 22.2 36.9 0.0096 16.0 18.4 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 GBG59724.1 - 0.0021 18.6 29.2 0.0064 17.0 16.3 2.0 1 1 1 2 2 2 2 Fez1 PCRF PF03462.18 GBG59724.1 - 0.013 15.4 5.5 0.013 15.4 5.5 2.2 1 1 1 2 2 2 0 PCRF domain TMF_TATA_bd PF12325.8 GBG59724.1 - 0.014 15.6 7.4 0.014 15.6 7.4 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 GBG59724.1 - 0.015 15.6 7.9 0.015 15.6 7.9 3.1 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 GBG59724.1 - 0.021 13.7 31.6 0.22 10.4 14.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein NUDE_C PF04880.13 GBG59724.1 - 0.022 15.3 2.6 0.022 15.3 2.6 3.2 1 1 2 3 3 3 0 NUDE protein, C-terminal conserved region HIP1_clath_bdg PF16515.5 GBG59724.1 - 0.042 14.4 37.2 0.52 11.0 4.1 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MAD PF05557.13 GBG59724.1 - 0.085 11.2 25.9 0.13 10.6 25.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein BAR_2 PF10455.9 GBG59724.1 - 0.13 11.4 13.2 0.29 10.2 3.4 2.2 1 1 1 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking THOC7 PF05615.13 GBG59724.1 - 0.2 12.0 32.7 0.049 13.9 7.1 3.3 1 1 2 3 3 3 0 Tho complex subunit 7 GAS PF13851.6 GBG59724.1 - 0.25 10.6 35.1 2.9 7.2 7.4 3.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.9 GBG59724.1 - 0.26 10.2 23.1 0.16 10.9 4.9 2.1 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 YscO PF07321.12 GBG59724.1 - 0.27 11.2 38.0 0.58 10.1 24.5 2.4 1 1 1 2 2 2 0 Type III secretion protein YscO betaPIX_CC PF16523.5 GBG59724.1 - 0.27 11.1 15.8 0.52 10.2 0.7 3.2 1 1 2 3 3 3 0 betaPIX coiled coil PRKG1_interact PF15898.5 GBG59724.1 - 0.28 12.1 28.9 0.24 12.3 10.4 3.5 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DPM3 PF08285.11 GBG59724.1 - 0.43 10.8 1.9 3.9 7.7 0.2 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ATG16 PF08614.11 GBG59724.1 - 0.5 10.6 39.9 0.087 13.0 16.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 GBG59724.1 - 0.83 9.7 33.7 7.5 6.6 8.5 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Leu_zip PF15294.6 GBG59724.1 - 0.93 8.9 24.8 3.6 7.0 4.2 2.1 1 1 1 2 2 2 0 Leucine zipper FliJ PF02050.16 GBG59724.1 - 0.98 9.7 37.8 2.3 8.5 19.2 2.9 1 1 1 2 2 2 0 Flagellar FliJ protein TFIIA PF03153.13 GBG59724.1 - 1.3 9.0 18.1 1.7 8.6 18.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IL2 PF00715.17 GBG59724.1 - 1.3 9.0 5.3 1.2 9.1 3.1 2.0 1 1 1 2 2 2 0 Interleukin 2 SHE3 PF17078.5 GBG59724.1 - 1.3 8.7 16.2 2.6 7.7 16.0 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 YabA PF06156.13 GBG59724.1 - 1.9 9.1 25.4 6.1 7.5 3.9 3.7 1 1 3 4 4 4 0 Initiation control protein YabA DUF4201 PF13870.6 GBG59724.1 - 2 8.1 27.5 0.3 10.8 5.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) EzrA PF06160.12 GBG59724.1 - 2.1 6.4 23.5 3.3 5.8 11.6 2.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA APC_N_CC PF16689.5 GBG59724.1 - 2.3 8.4 8.6 6 7.0 3.0 3.6 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain DUF2408 PF10303.9 GBG59724.1 - 2.6 8.6 16.8 1e+03 0.2 16.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Golgin_A5 PF09787.9 GBG59724.1 - 3.3 7.1 33.8 5.9 6.3 16.4 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 UPF0242 PF06785.11 GBG59724.1 - 3.3 7.8 32.5 0.37 10.9 18.8 3.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 GBG59724.1 - 3.4 8.1 12.7 37 4.8 1.0 5.1 2 2 2 5 5 5 0 Flagella accessory protein C (FlaC) MHB PF16525.5 GBG59724.1 - 4.9 7.5 11.6 2.1 8.7 1.0 3.7 1 1 1 3 3 3 0 Haemophore, haem-binding DUF4407 PF14362.6 GBG59724.1 - 5.2 6.3 28.2 47 3.2 26.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc29 PF17082.5 GBG59724.1 - 5.5 6.8 15.2 8.7 6.1 15.2 1.3 1 1 0 1 1 1 0 Spindle Pole Component 29 Surfac_D-trimer PF09006.11 GBG59724.1 - 5.6 6.9 14.1 0.13 12.2 1.3 3.2 2 1 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Seryl_tRNA_N PF02403.22 GBG59724.1 - 5.8 7.2 21.1 0.99 9.7 5.8 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.9 GBG59724.1 - 6.5 7.5 22.6 2 9.2 5.6 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 GBG59724.1 - 7.6 7.1 37.1 2.3 8.8 9.3 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region Fungal_TACC PF12709.7 GBG59724.1 - 8.2 7.0 20.3 2.6 8.6 0.3 5.1 1 1 3 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins Radical_SAM PF04055.21 GBG59725.1 - 0.0035 17.8 0.2 0.0058 17.0 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily RVT_1 PF00078.27 GBG59726.1 - 1.3e-28 100.0 0.0 2.4e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59726.1 - 1.1e-18 67.0 0.1 1.2e-14 54.2 0.0 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG59726.1 - 6.6e-12 45.7 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG59726.1 - 0.0023 18.1 0.0 0.007 16.6 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Herpes_US12 PF05363.12 GBG59726.1 - 0.058 14.1 0.5 0.16 12.7 0.5 1.7 1 0 0 1 1 1 0 Herpesvirus US12 family CCD48 PF15799.5 GBG59726.1 - 0.065 11.6 2.5 0.1 10.9 2.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF2385 PF09539.10 GBG59726.1 - 0.14 12.7 0.2 1.6 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) PIG-L PF02585.17 GBG59726.1 - 0.28 11.8 2.9 16 6.1 0.5 3.8 4 0 0 4 4 4 0 GlcNAc-PI de-N-acetylase zf-CCHC_2 PF13696.6 GBG59726.1 - 0.9 9.4 3.2 1.8 8.4 3.2 1.5 1 0 0 1 1 1 0 Zinc knuckle bZIP_2 PF07716.15 GBG59726.1 - 3.7 7.7 9.6 0.42 10.7 2.9 2.6 2 0 0 2 2 2 0 Basic region leucine zipper RVT_1 PF00078.27 GBG59727.1 - 1.5e-24 86.7 0.0 3.2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59727.1 - 2.2e-19 69.3 0.2 5.5e-19 68.0 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG59727.1 - 3.1e-19 68.8 0.0 1e-18 67.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59727.1 - 1.2e-08 35.2 0.0 6e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59727.1 - 4.2e-05 23.7 0.1 0.00023 21.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG59727.1 - 0.00098 19.4 1.6 0.024 14.9 0.1 3.7 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG59727.1 - 0.038 14.2 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG59727.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain P_C PF06640.11 GBG59727.1 - 0.91 9.6 6.9 0.93 9.6 1.3 2.6 2 0 0 2 2 2 0 P protein C-terminus AIF-MLS PF14962.6 GBG59727.1 - 3 7.7 6.4 2.9 7.8 4.6 1.8 1 1 0 1 1 1 0 Mitochondria Localisation Sequence RT_RNaseH_2 PF17919.1 GBG59728.1 - 6.3e-26 90.3 0.0 1.3e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59728.1 - 1e-20 73.9 0.0 2.1e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59729.1 - 6.1e-19 68.4 0.0 9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG59729.1 - 3e-08 34.2 0.0 6.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59729.1 - 2.4e-06 27.3 0.0 5.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG59729.1 - 7.2e-06 26.5 0.0 1.3e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG59729.1 - 0.0023 17.7 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG59730.1 - 0.00015 22.0 0.1 0.0017 18.6 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein RNR_Alpha PF17975.1 GBG59730.1 - 0.15 12.6 0.4 1.6 9.3 0.0 2.3 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain TMF_TATA_bd PF12325.8 GBG59730.1 - 0.17 12.1 0.8 0.96 9.7 0.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Senescence_reg PF04520.13 GBG59730.1 - 0.29 12.0 6.2 0.13 13.1 1.7 2.4 3 0 0 3 3 3 0 Senescence regulator Radical_SAM PF04055.21 GBG59731.1 - 3.8e-06 27.4 0.0 5.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily RT_RNaseH_2 PF17919.1 GBG59732.1 - 2.6e-31 107.6 0.0 8e-31 106.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59732.1 - 6.6e-31 106.7 0.0 1.8e-30 105.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RasGEF_N PF00618.20 GBG59732.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 RasGEF N-terminal motif DRY_EERY PF09750.9 GBG59732.1 - 1 9.6 8.1 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Alternative splicing regulator BATS PF06968.13 GBG59733.1 - 2.8e-16 59.4 0.1 1.2e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain HALZ PF02183.18 GBG59733.1 - 0.055 13.7 2.3 0.13 12.5 2.3 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper CENP-H PF05837.12 GBG59733.1 - 0.5 10.8 0.0 0.5 10.8 0.0 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 GBG59733.1 - 1.2 8.4 7.6 3.4 6.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SF3A2 PF16835.5 GBG59734.1 - 3.4e-35 120.3 0.2 4.7e-35 119.8 0.2 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 GBG59734.1 - 2.8e-06 27.5 1.3 4.4e-06 26.9 1.3 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 GBG59734.1 - 0.0016 18.4 0.7 0.0026 17.7 0.7 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Exog_C PF18026.1 GBG59735.1 - 0.14 12.3 2.2 4.4 7.4 0.1 3.3 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain RT_RNaseH_2 PF17919.1 GBG59736.1 - 6.1e-33 112.8 0.1 1.2e-32 111.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59736.1 - 3.1e-29 101.3 0.1 7e-29 100.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59736.1 - 3.4e-15 56.2 0.0 5.8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syja_N PF02383.18 GBG59737.1 - 3.3e-57 194.2 0.3 4.6e-57 193.7 0.3 1.2 1 0 0 1 1 1 1 SacI homology domain RVP_2 PF08284.11 GBG59737.1 - 8.3e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59737.1 - 0.0021 18.7 0.0 0.0047 17.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A3 PF02160.15 GBG59737.1 - 0.0049 16.4 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 Cauliflower mosaic virus peptidase (A3) gag-asp_proteas PF13975.6 GBG59737.1 - 0.013 16.0 0.0 0.034 14.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG59738.1 - 4.3e-14 52.7 0.0 9.7e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59738.1 - 7.8e-11 41.9 0.1 2.4e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59738.1 - 6.6e-07 29.2 0.0 2.4e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59738.1 - 1.6e-05 25.5 0.1 5.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59738.1 - 0.00041 20.8 0.5 0.0024 18.4 0.1 2.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG59738.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Sirohm_synth_M PF14824.6 GBG59738.1 - 0.075 12.5 0.2 0.27 10.7 0.1 2.1 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central DUF4392 PF14336.6 GBG59738.1 - 0.1 12.0 0.4 0.6 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Phage_GPO PF05929.11 GBG59738.1 - 0.75 9.4 4.9 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3629 PF12302.8 GBG59738.1 - 8.3 5.8 7.6 17 4.8 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Syja_N PF02383.18 GBG59739.1 - 6.9e-14 51.9 0.1 1.1e-13 51.2 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain PT PF04886.12 GBG59739.1 - 0.097 12.2 15.6 0.17 11.4 15.6 1.4 1 0 0 1 1 1 0 PT repeat DUF659 PF04937.15 GBG59740.1 - 1.1e-21 77.3 0.0 2.3e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59740.1 - 2.9e-12 46.2 0.1 7.2e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Integrase_H2C2 PF17921.1 GBG59741.1 - 2e-17 63.0 0.3 4e-17 62.1 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59741.1 - 0.0019 18.3 0.0 0.0052 17.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain FtsK_4TM PF13491.6 GBG59741.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE Retrotrans_gag PF03732.17 GBG59741.1 - 0.029 14.6 0.0 0.094 13.0 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein DUF3863 PF12979.7 GBG59741.1 - 0.05 12.5 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) zf-CCHC_3 PF13917.6 GBG59741.1 - 0.074 13.0 3.7 0.2 11.7 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF2391 PF09622.10 GBG59741.1 - 0.23 10.8 2.4 0.36 10.1 2.4 1.2 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) GCV_H PF01597.19 GBG59745.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein gag-asp_proteas PF13975.6 GBG59746.1 - 1e-06 29.2 0.0 3.1e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59746.1 - 1.8e-06 27.8 0.0 4.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59746.1 - 2.2e-06 28.2 0.0 5.4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG59746.1 - 5.4e-05 23.0 0.0 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease CENP-K PF11802.8 GBG59746.1 - 0.094 12.3 3.5 0.17 11.4 3.5 1.3 1 0 0 1 1 1 0 Centromere-associated protein K TMEM247 PF15444.6 GBG59746.1 - 0.31 11.1 0.1 0.31 11.1 0.1 1.6 2 0 0 2 2 2 0 Transmembrane protein 247 Cupin_8 PF13621.6 GBG59747.1 - 1.1 8.9 6.9 1.3 8.6 6.9 1.3 1 0 0 1 1 1 0 Cupin-like domain TMF_TATA_bd PF12325.8 GBG59748.1 - 3.4 7.9 13.5 3.7 7.8 0.3 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3006 PF11213.8 GBG59748.1 - 5 7.4 5.6 9.7 6.5 3.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) RVT_1 PF00078.27 GBG59749.1 - 7e-30 104.2 0.1 1.6e-29 103.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59749.1 - 8.2e-25 86.8 0.0 2e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59749.1 - 5.6e-22 78.0 0.0 1.4e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59749.1 - 0.0013 18.8 0.2 0.0032 17.5 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain AAA_13 PF13166.6 GBG59750.1 - 0.035 12.8 0.4 0.059 12.0 0.4 1.3 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.22 GBG59750.1 - 0.11 12.8 4.2 0.33 11.2 4.2 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4674 PF15719.5 GBG59750.1 - 0.2 11.7 10.7 0.42 10.6 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Mitofilin PF09731.9 GBG59750.1 - 0.23 10.2 5.8 0.33 9.7 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Complex1_49kDa PF00346.19 GBG59750.1 - 0.29 10.2 1.9 3 6.9 0.0 2.2 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Osteoregulin PF07175.11 GBG59750.1 - 0.45 10.7 7.7 0.86 9.8 7.7 1.4 1 0 0 1 1 1 0 Osteoregulin DDE_Tnp_4 PF13359.6 GBG59751.1 - 4.7e-27 94.6 0.0 7.8e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG59751.1 - 2.2e-18 66.6 0.0 3.1e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG59751.1 - 2.8e-05 23.9 3.0 0.0003 20.5 0.9 2.7 2 1 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG59752.1 - 1.8e-05 25.0 1.6 2.7e-05 24.5 1.6 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG59752.1 - 0.00039 20.4 0.4 0.00056 19.9 0.4 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG59753.1 - 8.1e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG59754.1 - 0.006 16.8 0.5 0.039 14.2 0.2 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein DUF1664 PF07889.12 GBG59754.1 - 0.087 12.9 1.3 2 8.5 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Mer2 PF09074.10 GBG59754.1 - 0.21 11.4 3.9 0.19 11.5 0.9 2.1 2 0 0 2 2 2 0 Mer2 RT_RNaseH PF17917.1 GBG59755.1 - 1.2e-22 80.2 0.0 1.2e-21 77.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59755.1 - 1.5e-19 69.9 0.0 3.7e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59756.1 - 3.3e-24 85.7 0.0 5.2e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59756.1 - 5.9e-16 58.3 0.0 1.8e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG59756.1 - 2.3e-06 28.2 2.4 0.11 13.5 0.0 4.8 5 1 0 5 5 5 2 WD domain, G-beta repeat RT_RNaseH PF17917.1 GBG59756.1 - 1.6e-05 25.1 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SlyX PF04102.12 GBG59756.1 - 0.041 14.5 0.3 0.73 10.5 0.0 2.9 3 0 0 3 3 3 0 SlyX PNMA PF14893.6 GBG59756.1 - 0.063 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 PNMA RT_RNaseH_2 PF17919.1 GBG59757.1 - 1.7e-22 79.3 0.0 6.1e-22 77.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59757.1 - 1.9e-18 66.7 0.0 8.5e-18 64.6 0.0 2.1 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59757.1 - 9.9e-16 57.6 0.7 2.8e-14 52.9 0.3 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59757.1 - 6e-07 29.2 0.1 1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG59757.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Presenilin PF01080.17 GBG59758.1 - 0.2 10.4 1.1 0.22 10.2 1.1 1.2 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 GBG59758.1 - 1.4 9.0 15.5 1.7 8.7 15.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RT_RNaseH_2 PF17919.1 GBG59760.1 - 4.8e-30 103.6 0.1 1.7e-29 101.8 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59760.1 - 7.9e-21 74.3 0.0 6.6e-20 71.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59760.1 - 0.05 13.9 0.1 0.3 11.4 0.0 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein RTA1 PF04479.13 GBG59761.1 - 0.14 11.7 19.5 32 4.0 0.0 9.4 4 3 8 12 12 12 0 RTA1 like protein FBA_3 PF08268.12 GBG59761.1 - 0.53 10.2 16.3 11 6.0 0.4 4.9 2 1 4 6 6 6 0 F-box associated domain PapC_C PF13953.6 GBG59761.1 - 0.92 9.4 46.8 2.8 7.8 0.5 10.4 2 1 10 13 13 13 0 PapC C-terminal domain zf-Paramyx-P PF13008.7 GBG59762.1 - 0.2 11.2 0.2 0.45 10.0 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein Asp_protease_2 PF13650.6 GBG59763.1 - 0.00033 21.2 0.0 0.0023 18.5 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59763.1 - 0.00053 20.5 0.1 0.0018 18.8 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG59763.1 - 0.032 14.5 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG59763.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease HEAT PF02985.22 GBG59764.1 - 7.4e-08 32.0 0.1 1.9e-05 24.5 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 GBG59764.1 - 1.8e-06 28.2 4.0 0.00016 22.0 0.3 3.1 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 GBG59764.1 - 3.1e-06 27.5 0.2 2.1e-05 24.9 0.0 2.5 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 GBG59764.1 - 0.085 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.6 GBG59764.1 - 0.13 11.9 0.0 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) Raptor_N PF14538.6 GBG59765.1 - 9.1e-41 139.2 0.0 2.5e-40 137.8 0.0 1.8 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain RVT_1 PF00078.27 GBG59765.1 - 4.1e-25 88.6 0.1 7.1e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59765.1 - 9.4e-25 86.6 0.0 2.5e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59765.1 - 2.7e-21 75.8 0.0 8e-21 74.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG59765.1 - 4.1e-06 27.4 0.0 2.5e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG59765.1 - 0.00017 21.3 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG59765.1 - 0.0011 19.5 0.0 0.0024 18.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG59765.1 - 0.0092 16.2 0.0 0.069 13.4 0.0 2.5 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG59765.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Chromo PF00385.24 GBG59765.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG59767.1 - 4.8e-31 108.0 0.0 7.3e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59767.1 - 8.9e-30 102.7 0.0 1.9e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59767.1 - 2.6e-22 79.1 0.0 6.5e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59767.1 - 2.4e-05 24.1 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59767.1 - 9.6e-05 23.0 0.0 0.00031 21.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59767.1 - 9.8e-05 22.8 0.0 0.00026 21.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG59767.1 - 0.00023 20.9 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease CCD48 PF15799.5 GBG59767.1 - 0.0042 15.5 1.4 0.0074 14.6 1.4 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 HALZ PF02183.18 GBG59767.1 - 0.013 15.7 2.4 0.032 14.5 2.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper CCDC85 PF10226.9 GBG59767.1 - 0.094 12.4 1.6 0.1 12.2 0.2 1.8 2 0 0 2 2 2 0 CCDC85 family bZIP_2 PF07716.15 GBG59767.1 - 0.17 12.0 10.1 0.18 11.9 3.6 2.7 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 GBG59767.1 - 0.36 10.6 2.2 1.3 8.9 2.2 1.9 1 0 0 1 1 1 0 Septum formation initiator ABC_tran_CTD PF16326.5 GBG59767.1 - 3.3 8.0 5.6 1.7 9.0 1.9 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain NAPRTase_C PF17956.1 GBG59768.1 - 1.6e-14 54.2 0.7 2.6e-14 53.6 0.7 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain rve PF00665.26 GBG59768.1 - 0.0072 16.5 0.0 0.019 15.1 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 GBG59770.1 - 3.5e-11 43.3 0.0 7.3e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain PapC_C PF13953.6 GBG59771.1 - 0.0073 16.1 29.1 7.4 6.5 0.3 8.1 3 2 5 9 9 9 7 PapC C-terminal domain SH3_19 PF18597.1 GBG59771.1 - 0.016 15.0 34.5 15 5.5 0.1 9.2 9 0 0 9 9 9 0 Myosin X N-terminal SH3 domain RTA1 PF04479.13 GBG59771.1 - 0.047 13.3 14.7 18 4.8 0.1 7.1 4 3 4 8 8 8 0 RTA1 like protein rve PF00665.26 GBG59772.1 - 2.5e-12 47.0 0.0 1.8e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain NAPRTase_C PF17956.1 GBG59773.1 - 1.3e-16 61.0 0.2 3.2e-16 59.7 0.2 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 GBG59773.1 - 0.0021 17.7 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family partial_CstF PF15861.5 GBG59773.1 - 0.11 12.3 1.6 0.22 11.3 1.6 1.4 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain YlqD PF11068.8 GBG59773.1 - 2.7 8.4 16.7 1.1 9.7 9.5 2.2 1 1 1 2 2 2 0 YlqD protein DUF4061 PF13270.6 GBG59773.1 - 3 8.2 6.4 1.5 9.1 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) RVT_1 PF00078.27 GBG59774.1 - 1.4e-25 90.1 0.1 2.1e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59774.1 - 4.6e-23 81.2 0.0 1.1e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59774.1 - 1.5e-20 73.4 0.0 2.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59774.1 - 1.3e-17 63.6 2.6 2.8e-17 62.6 0.7 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG59774.1 - 1e-07 32.1 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG59775.1 - 3.2e-33 113.8 0.0 6.9e-33 112.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59775.1 - 4.8e-29 100.7 0.0 9.7e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59775.1 - 2.1e-25 89.6 0.0 3.8e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAPRTase_N PF17767.1 GBG59775.1 - 3.2e-19 69.5 0.2 4.4e-17 62.6 0.1 3.0 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Chromo PF00385.24 GBG59775.1 - 0.00023 21.0 0.0 0.057 13.3 0.1 3.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain NAPRTase PF04095.16 GBG59775.1 - 0.017 14.8 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Retrotrans_gag PF03732.17 GBG59775.1 - 0.025 14.8 0.1 2.4 8.5 0.0 3.9 3 0 0 3 3 3 0 Retrotransposon gag protein DASH_Dad3 PF08656.10 GBG59775.1 - 0.16 12.0 0.6 0.61 10.2 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 RT_RNaseH_2 PF17919.1 GBG59776.1 - 1.5e-12 47.4 0.0 3.9e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59776.1 - 2.3e-12 47.1 0.0 6.4e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59776.1 - 0.00057 20.4 0.0 0.0049 17.4 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59776.1 - 0.017 15.7 0.0 0.13 12.9 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Ntox14 PF15522.6 GBG59777.1 - 0.069 12.6 0.2 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Novel toxin 14 ERM PF00769.19 GBG59777.1 - 0.99 9.2 15.2 0.76 9.5 11.8 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Chlorophyllase PF07224.11 GBG59778.1 - 0.00013 21.1 0.0 0.42 9.6 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase PAF-AH_p_II PF03403.13 GBG59778.1 - 0.00014 20.5 0.3 0.0031 16.1 0.1 2.2 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 GBG59778.1 - 0.00028 19.9 0.0 0.11 11.4 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme RVT_1 PF00078.27 GBG59779.1 - 1.1e-27 97.0 0.0 2e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59779.1 - 3.9e-18 65.3 0.0 1.1e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG59779.1 - 2.9e-17 62.5 0.3 4.8e-13 49.0 0.3 2.5 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59779.1 - 1.6e-16 60.5 0.1 3.3e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59779.1 - 4.6e-11 43.0 0.0 1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG59779.1 - 0.03 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG59780.1 - 1.5e-30 105.2 0.0 3.9e-30 103.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59780.1 - 6.2e-30 103.6 0.0 1.4e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG59780.1 - 0.077 12.6 2.4 0.26 10.9 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG59781.1 - 3.5e-35 120.0 0.1 5.8e-35 119.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59781.1 - 1.2e-31 109.1 0.2 1.9e-31 108.4 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4619 PF15398.6 GBG59782.1 - 0.031 13.8 16.3 0.028 14.0 15.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4619) Spore_YhcN_YlaJ PF09580.10 GBG59782.1 - 0.034 14.2 3.1 0.034 14.2 3.1 2.0 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Proteasome PF00227.26 GBG59785.1 - 1.2e-60 204.2 0.0 1.5e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GBG59785.1 - 7e-14 51.2 0.0 1.7e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TSP_1 PF00090.19 GBG59786.1 - 0.098 12.9 0.5 0.22 11.8 0.5 1.5 1 0 0 1 1 1 0 Thrombospondin type 1 domain RT_RNaseH_2 PF17919.1 GBG59787.1 - 3.5e-30 104.0 0.0 1.1e-29 102.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59787.1 - 4.7e-30 104.0 0.1 1.1e-29 102.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59787.1 - 4.5e-07 29.7 0.0 9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59787.1 - 1.1e-05 26.0 0.0 2.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59787.1 - 0.00022 21.7 0.0 0.0011 19.5 0.0 2.2 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG59787.1 - 0.0034 17.2 0.0 0.0092 15.8 0.0 1.7 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Phage_lysozyme PF00959.19 GBG59787.1 - 0.11 13.0 0.5 2.2 8.8 0.0 3.2 3 0 0 3 3 3 0 Phage lysozyme Asp_protease PF09668.10 GBG59787.1 - 0.13 12.0 0.0 1.1 9.1 0.0 2.3 2 1 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG59788.1 - 1.9e-14 53.5 0.0 5e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG59788.1 - 4.1e-05 24.2 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59788.1 - 8.3e-05 23.1 0.0 0.00026 21.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG59788.1 - 0.00025 21.3 0.0 0.00053 20.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59788.1 - 0.012 15.9 0.0 0.044 14.0 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG59788.1 - 0.015 15.1 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF4187 PF13821.6 GBG59789.1 - 0.012 15.4 0.4 0.038 13.8 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG59789.1 - 0.038 14.3 1.6 0.55 10.5 0.1 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG59790.1 - 2.3e-30 105.0 0.1 5.1e-30 103.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59790.1 - 1.7e-28 98.6 0.0 3.8e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG59790.1 - 0.021 14.5 0.1 0.021 14.5 0.1 3.0 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase BAF1_ABF1 PF04684.13 GBG59790.1 - 5.8 5.9 14.0 8.3 5.3 14.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RT_RNaseH PF17917.1 GBG59791.1 - 5.5e-48 161.6 3.2 2.7e-29 101.5 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59791.1 - 2.5e-38 130.1 0.0 2.1e-28 98.3 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59791.1 - 7.5e-34 117.2 0.1 1.3e-33 116.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59791.1 - 6.2e-22 77.5 0.1 5.1e-10 39.3 0.0 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain GHMP_kinases_N PF00288.26 GBG59791.1 - 7.1e-12 45.4 12.2 2.1e-06 27.9 0.2 3.2 3 0 0 3 3 3 2 GHMP kinases N terminal domain zf-H2C2 PF09337.10 GBG59791.1 - 0.0021 18.2 0.1 0.59 10.4 0.0 2.8 2 0 0 2 2 2 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG59794.1 - 3.9e-33 113.5 0.0 9.5e-33 112.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59794.1 - 1.4e-28 100.0 0.1 2.8e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59794.1 - 9.8e-28 96.5 0.1 2.2e-27 95.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59794.1 - 7.2e-19 67.6 0.1 1.7e-18 66.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG59794.1 - 2.3e-05 24.9 0.0 0.00022 21.7 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59794.1 - 0.00036 21.1 0.0 0.0078 16.8 0.0 2.9 3 0 0 3 3 3 1 Aspartyl protease rve PF00665.26 GBG59794.1 - 0.03 14.5 0.0 0.08 13.1 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG59795.1 - 2.7e-33 114.0 0.0 7.2e-33 112.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59795.1 - 1e-28 100.4 0.1 2e-28 99.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59795.1 - 7.2e-28 97.0 0.1 1.7e-27 95.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59795.1 - 1.7e-05 25.3 0.0 0.00017 22.1 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59795.1 - 0.0003 21.4 0.0 0.0059 17.2 0.0 2.7 2 0 0 2 2 2 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG59796.1 - 2.9e-13 49.7 0.0 6.4e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59796.1 - 1.4e-12 47.9 0.0 2.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG59796.1 - 0.0097 15.7 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG59796.1 - 0.088 13.4 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG59797.1 - 1e-13 51.1 0.0 2.5e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59797.1 - 4.6e-13 49.4 0.0 8.2e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG59797.1 - 0.0033 17.2 0.0 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG59798.1 - 0.00016 21.9 0.2 0.00027 21.2 0.2 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein VWA_N PF08399.11 GBG59798.1 - 0.034 14.6 0.0 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 VWA N-terminal rve PF00665.26 GBG59800.1 - 1.2e-08 35.1 0.1 4.6e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG59800.1 - 0.0015 18.8 0.1 0.054 13.8 0.1 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein Tudor-knot PF11717.8 GBG59800.1 - 0.0023 17.8 0.0 0.0066 16.3 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RVT_1 PF00078.27 GBG59800.1 - 0.026 14.0 0.0 0.08 12.4 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG59800.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Zip PF02535.22 GBG59800.1 - 3.5 6.8 7.4 1.2 8.3 2.4 2.3 2 1 0 2 2 2 0 ZIP Zinc transporter AAA PF00004.29 GBG59801.1 - 5.4e-40 136.9 0.1 2.9e-39 134.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RT_RNaseH_2 PF17919.1 GBG59801.1 - 6.6e-18 64.6 0.0 2.2e-17 62.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AAA_lid_3 PF17862.1 GBG59801.1 - 2.2e-12 46.6 2.8 8.1e-12 44.7 2.8 2.0 1 0 0 1 1 1 1 AAA+ lid domain RT_RNaseH PF17917.1 GBG59801.1 - 1.7e-07 31.5 0.0 4.8e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59801.1 - 1.7e-07 31.1 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease AAA_16 PF13191.6 GBG59801.1 - 9.3e-05 22.9 4.4 0.0024 18.3 0.1 3.9 3 1 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.14 GBG59801.1 - 0.00013 22.2 0.0 0.00043 20.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Asp_protease_2 PF13650.6 GBG59801.1 - 0.00013 22.6 2.4 0.00022 21.8 0.0 2.7 3 0 0 3 3 1 1 Aspartyl protease RuvB_N PF05496.12 GBG59801.1 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GBG59801.1 - 0.0017 18.3 0.0 0.0064 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GBG59801.1 - 0.0021 18.4 0.1 0.22 11.8 0.1 2.9 1 1 0 1 1 1 1 AAA domain gag-asp_proteas PF13975.6 GBG59801.1 - 0.0023 18.4 1.6 0.01 16.4 0.0 3.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease AAA_33 PF13671.6 GBG59801.1 - 0.0024 18.0 2.8 0.025 14.8 0.0 3.5 3 1 0 3 3 3 1 AAA domain DUF1758 PF05585.12 GBG59801.1 - 0.0047 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Putative peptidase (DUF1758) TIP49 PF06068.13 GBG59801.1 - 0.0053 16.0 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_11 PF13086.6 GBG59801.1 - 0.034 13.9 9.9 0.04 13.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 GBG59801.1 - 0.049 14.1 0.0 0.049 14.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 GBG59801.1 - 0.049 14.0 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 GBG59801.1 - 0.11 12.4 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GBG59801.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF1344 PF07076.11 GBG59801.1 - 0.18 11.7 0.1 30 4.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) AAA_19 PF13245.6 GBG59801.1 - 0.23 11.8 1.2 0.53 10.6 0.0 2.2 2 0 0 2 2 1 0 AAA domain ANAPC_CDC26 PF10471.9 GBG59801.1 - 6.7 7.6 10.8 0.76 10.6 4.2 3.0 2 0 0 2 2 1 0 Anaphase-promoting complex APC subunit CDC26 RT_RNaseH_2 PF17919.1 GBG59802.1 - 2.2e-25 88.6 0.0 7.3e-25 86.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59802.1 - 2.1e-24 85.8 0.0 5.1e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59802.1 - 0.00026 21.2 6.9 0.0008 19.6 0.1 3.6 3 1 0 3 3 3 1 Retrotransposon gag protein Med14 PF08638.11 GBG59802.1 - 0.059 12.8 0.1 0.25 10.7 0.1 2.0 2 0 0 2 2 2 0 Mediator complex subunit MED14 FUSC PF04632.12 GBG59802.1 - 0.15 10.6 4.4 0.26 9.8 4.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4404 PF14357.6 GBG59802.1 - 0.2 12.3 3.7 0.16 12.6 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) M PF02370.16 GBG59802.1 - 5.4 7.9 5.4 68 4.5 3.2 2.7 2 0 0 2 2 2 0 M protein repeat RT_RNaseH_2 PF17919.1 GBG59803.1 - 1.1e-55 185.8 0.0 1.1e-31 108.8 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59803.1 - 1.3e-55 186.1 0.2 2.3e-28 98.5 0.1 3.1 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59803.1 - 5.3e-38 130.7 0.3 1.7e-26 93.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59803.1 - 1.9e-34 117.5 1.2 2.6e-18 65.9 0.3 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain AAA PF00004.29 GBG59803.1 - 2.6e-26 92.6 0.0 1.3e-14 54.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG59803.1 - 1.7e-13 50.1 0.5 4.9e-13 48.7 0.5 1.9 1 0 0 1 1 1 1 AAA+ lid domain gag-asp_proteas PF13975.6 GBG59803.1 - 4.9e-08 33.4 0.0 1.7e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG59803.1 - 7.1e-08 32.7 0.0 3.4e-07 30.5 0.0 2.3 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG59803.1 - 1.5e-07 31.9 0.0 3.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59803.1 - 3.4e-06 26.9 0.0 7.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59803.1 - 1.5e-05 24.8 0.0 4.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG59803.1 - 2.2 8.6 6.8 0.41 10.9 0.1 3.3 4 0 0 4 4 4 0 Retrotransposon gag protein Nop53 PF07767.11 GBG59803.1 - 9.8 5.4 7.9 20 4.4 7.9 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF188 PF02639.14 GBG59804.1 - 0.00024 20.7 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 RVT_1 PF00078.27 GBG59805.1 - 3.7e-28 98.5 0.1 5.6e-28 98.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59805.1 - 1.9e-11 43.9 0.0 5.3e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59805.1 - 0.0055 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59806.1 - 9.3e-20 70.5 0.3 1.9e-19 69.5 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG59806.1 - 3.4e-16 59.5 0.0 8.2e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG59806.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 GBG59806.1 - 0.022 14.5 0.0 0.077 12.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain LMBR1 PF04791.16 GBG59807.1 - 1.2 8.0 4.7 1.5 7.6 4.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Leo1 PF04004.13 GBG59808.1 - 2.1e-42 144.8 0.9 2.1e-42 144.8 0.9 3.2 2 1 0 2 2 2 1 Leo1-like protein RVT_1 PF00078.27 GBG59808.1 - 1.4e-26 93.4 0.1 2.5e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2154 PF09922.9 GBG59808.1 - 0.034 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Cell wall-active antibiotics response 4TMS YvqF RVT_1 PF00078.27 GBG59809.1 - 1.6e-06 27.8 0.0 3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4373 PF14297.6 GBG59809.1 - 0.076 13.8 1.4 0.34 11.7 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4373) DUF4852 PF16144.5 GBG59809.1 - 0.079 13.1 0.3 0.26 11.4 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) Suf PF05843.14 GBG59809.1 - 0.18 11.8 1.6 0.29 11.1 1.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Retrotrans_gag PF03732.17 GBG59809.1 - 0.58 10.5 3.1 0.55 10.5 0.9 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Presenilin PF01080.17 GBG59809.1 - 8.4 5.0 5.4 12 4.5 5.4 1.1 1 0 0 1 1 1 0 Presenilin rve PF00665.26 GBG59810.1 - 5.8e-11 42.6 0.0 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG59810.1 - 0.021 14.6 0.0 0.092 12.5 0.0 2.2 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 GBG59810.1 - 0.023 15.3 0.0 0.053 14.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG59810.1 - 0.037 14.3 0.1 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG59810.1 - 0.052 13.8 0.7 0.24 11.7 0.3 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein DUF659 PF04937.15 GBG59811.1 - 1.1e-32 113.0 0.2 2.6e-32 111.8 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG59811.1 - 5.4e-14 52.0 0.0 1.5e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59811.1 - 1.8e-11 44.3 0.0 5.6e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG59811.1 - 0.00067 19.4 0.7 0.0016 18.2 0.2 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.17 GBG59811.1 - 0.014 15.7 0.0 0.051 13.9 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein rve_3 PF13683.6 GBG59811.1 - 0.13 12.1 0.0 0.45 10.3 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Pkinase_Tyr PF07714.17 GBG59812.1 - 5.8e-21 74.9 0.1 1.4e-20 73.7 0.0 1.6 2 0 0 2 2 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG59812.1 - 8.1e-16 58.2 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Filament PF00038.21 GBG59812.1 - 0.0015 18.2 14.9 0.0024 17.5 14.9 1.3 1 0 0 1 1 1 1 Intermediate filament protein TPH PF13868.6 GBG59812.1 - 0.019 13.5 25.8 0.025 13.1 25.8 1.1 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain TSKS PF15358.6 GBG59812.1 - 0.03 12.7 7.4 0.04 12.3 7.4 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Spc7 PF08317.11 GBG59812.1 - 0.035 13.0 19.3 0.054 12.4 19.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 GBG59812.1 - 0.038 11.5 14.7 0.053 11.1 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 GBG59812.1 - 0.065 13.3 0.3 0.14 12.2 0.2 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 GBG59812.1 - 0.069 13.4 11.4 0.17 12.2 11.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) FUSC PF04632.12 GBG59812.1 - 0.074 11.6 2.3 0.099 11.2 2.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 GBG59812.1 - 0.12 11.9 7.1 0.18 11.4 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 GBG59812.1 - 0.12 12.4 24.5 0.037 14.1 9.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 GBG59812.1 - 0.14 12.2 13.4 1.2 9.2 8.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 GBG59812.1 - 0.16 11.0 14.1 0.26 10.3 14.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HMMR_N PF15905.5 GBG59812.1 - 0.18 11.3 20.0 0.29 10.6 20.0 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DHR10 PF18595.1 GBG59812.1 - 0.18 11.8 22.1 0.18 11.9 20.5 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain AAA_11 PF13086.6 GBG59812.1 - 0.22 11.3 7.0 0.33 10.7 7.0 1.2 1 0 0 1 1 1 0 AAA domain MCPsignal PF00015.21 GBG59812.1 - 0.24 11.2 5.9 0.36 10.6 5.2 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 GBG59812.1 - 0.48 10.7 2.1 1.2 9.4 2.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.19 GBG59812.1 - 0.53 8.1 8.7 0.7 7.7 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.6 GBG59812.1 - 0.73 8.4 10.4 1.1 7.8 10.4 1.2 1 0 0 1 1 1 0 AAA domain ING PF12998.7 GBG59812.1 - 0.87 10.2 13.1 0.27 11.8 7.7 2.4 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ADIP PF11559.8 GBG59812.1 - 1.7 8.7 18.0 0.84 9.7 3.6 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 GBG59812.1 - 1.8 7.7 16.2 1.4 8.1 5.7 2.7 2 1 1 3 3 3 0 TMPIT-like protein BRE1 PF08647.11 GBG59812.1 - 2.6 8.2 18.3 0.29 11.2 2.9 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Vfa1 PF08432.10 GBG59812.1 - 3.3 8.0 10.7 5.5 7.3 10.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spc24 PF08286.11 GBG59812.1 - 3.9 7.8 15.8 1.3 9.3 2.5 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 LMBR1 PF04791.16 GBG59812.1 - 4 6.2 4.5 5 5.9 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-F_leu_zip PF10473.9 GBG59812.1 - 4 7.4 26.9 11 6.0 27.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 GBG59812.1 - 4.6 7.4 12.0 5.5 7.2 4.8 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF501 PF04417.12 GBG59812.1 - 4.9 7.0 9.6 3.1 7.6 6.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF501) YabA PF06156.13 GBG59812.1 - 6.4 7.5 16.6 7.5 7.2 1.4 2.7 1 1 1 2 2 2 0 Initiation control protein YabA HAUS6_N PF14661.6 GBG59812.1 - 6.6 6.2 11.1 11 5.5 11.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ATG16 PF08614.11 GBG59812.1 - 7.2 6.8 21.1 4.6 7.4 5.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.11 GBG59812.1 - 7.2 6.4 7.6 13 5.5 4.1 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Swi5 PF07061.11 GBG59812.1 - 8.1 6.6 12.2 24 5.1 5.3 2.9 2 1 1 3 3 3 0 Swi5 COG2 PF06148.11 GBG59812.1 - 9.6 6.3 14.1 28 4.8 0.2 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RT_RNaseH_2 PF17919.1 GBG59813.1 - 3.5e-20 71.9 0.0 7e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59813.1 - 4.6e-12 45.9 0.0 8.2e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59813.1 - 5.3e-09 36.3 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG59813.1 - 0.005 16.9 0.8 0.013 15.5 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG59813.1 - 0.0057 17.3 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59813.1 - 0.0083 16.7 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SDA1 PF05285.12 GBG59813.1 - 0.1 12.0 19.8 0.21 11.0 19.8 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG59813.1 - 0.77 7.9 21.1 1.4 7.1 21.1 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG59813.1 - 1.6 7.0 15.2 2.3 6.4 15.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-bind_4 PF13837.6 GBG59814.1 - 3.8e-07 30.4 4.4 3.8e-07 30.4 4.4 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG59814.1 - 0.0062 16.8 1.0 0.0062 16.8 1.0 2.7 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Prominin PF05478.11 GBG59814.1 - 0.1 10.6 0.0 0.16 9.9 0.0 1.3 1 0 0 1 1 1 0 Prominin T2SSM PF04612.12 GBG59814.1 - 0.1 12.6 3.4 0.16 12.0 0.2 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M TMPIT PF07851.13 GBG59814.1 - 0.89 8.7 2.0 1.7 7.8 2.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 GBG59814.1 - 9 6.4 11.0 22 5.1 11.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DDE_Tnp_4 PF13359.6 GBG59815.1 - 7.9e-23 80.9 0.1 3.3e-22 78.9 0.1 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG59815.1 - 9.5e-12 45.0 0.1 3.9e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG59815.1 - 0.0033 17.1 1.0 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG59815.1 - 0.01 16.2 0.0 0.031 14.7 0.0 1.8 1 0 0 1 1 1 0 Transposase DDE domain zf-CCHC PF00098.23 GBG59816.1 - 5.3e-07 29.4 1.7 1.2e-06 28.3 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG59816.1 - 0.021 14.5 0.8 0.051 13.3 0.8 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 GBG59816.1 - 0.022 14.6 1.4 0.05 13.5 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG59816.1 - 0.026 14.3 1.5 0.026 14.3 1.5 1.7 2 0 0 2 2 2 0 Zinc knuckle DUF2229 PF09989.9 GBG59816.1 - 0.11 12.2 0.4 0.15 11.7 0.4 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) RVT_1 PF00078.27 GBG59817.1 - 1.1e-27 97.1 0.0 1.9e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG59817.1 - 1.3e-21 77.1 0.0 3.2e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG59817.1 - 7.2e-16 58.3 0.0 2e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG59817.1 - 6.6e-09 36.3 0.1 0.07 14.0 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Tetraspanin PF00335.20 GBG59817.1 - 1.6e-08 34.6 3.8 3.5e-08 33.5 3.8 1.5 1 0 0 1 1 1 1 Tetraspanin family FPP PF05911.11 GBG59817.1 - 0.081 11.1 17.5 0.24 9.5 13.9 2.1 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF2207 PF09972.9 GBG59817.1 - 0.19 10.5 4.3 0.028 13.2 0.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FliD_C PF07195.12 GBG59817.1 - 0.4 10.0 5.3 0.15 11.4 2.1 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Spc7 PF08317.11 GBG59817.1 - 0.45 9.3 22.8 0.32 9.8 14.4 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4795 PF16043.5 GBG59817.1 - 0.64 9.6 16.8 3.1 7.4 10.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) AAA_11 PF13086.6 GBG59817.1 - 0.73 9.6 14.0 0.069 12.9 5.7 2.6 3 0 0 3 3 3 0 AAA domain UPF0242 PF06785.11 GBG59817.1 - 0.82 9.7 20.7 1.7 8.7 1.5 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HD_2 PF12917.7 GBG59817.1 - 0.99 9.1 4.9 2.3 7.9 4.9 1.6 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme GAS PF13851.6 GBG59817.1 - 2.1 7.7 23.8 2.2 7.6 13.2 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 GBG59817.1 - 2.7 6.8 18.3 6.5 5.5 13.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) tRNA-synt_His PF13393.6 GBG59817.1 - 2.7 7.2 6.8 3.2 7.0 4.6 2.1 2 0 0 2 2 2 0 Histidyl-tRNA synthetase DUF724 PF05266.14 GBG59817.1 - 3.8 7.3 18.7 1.4 8.7 12.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) LegC3_N PF18654.1 GBG59817.1 - 4 6.6 19.3 0.29 10.3 11.5 2.3 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain FUSC PF04632.12 GBG59817.1 - 5.6 5.4 8.2 1.1 7.7 2.2 2.5 3 0 0 3 3 3 0 Fusaric acid resistance protein family COG2 PF06148.11 GBG59817.1 - 5.7 7.0 19.0 0.57 10.3 4.3 3.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.6 GBG59817.1 - 6.8 5.2 12.5 0.63 8.6 5.2 2.2 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 GBG59817.1 - 7.1 6.1 13.1 9.8 5.6 6.5 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 GBG59817.1 - 7.3 7.1 10.3 8 6.9 0.7 3.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 GBG59817.1 - 8.3 5.6 17.7 33 3.6 10.3 3.2 3 0 0 3 3 3 0 TMPIT-like protein DUF1664 PF07889.12 GBG59817.1 - 9.3 6.3 18.9 0.077 13.0 6.1 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) DUF659 PF04937.15 GBG59819.1 - 8.6e-11 41.9 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pkinase_Tyr PF07714.17 GBG59820.1 - 2.7e-24 85.9 0.0 4.7e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG59820.1 - 3.1e-24 85.8 0.0 6.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG59820.1 - 6.1e-09 36.4 0.2 0.043 14.7 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Prefoldin PF02996.17 GBG59820.1 - 0.052 13.5 1.2 0.15 11.9 0.8 1.8 1 1 0 1 1 1 0 Prefoldin subunit DUF4164 PF13747.6 GBG59820.1 - 0.062 13.6 5.2 0.18 12.1 5.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 GBG59820.1 - 0.071 13.2 6.2 0.17 12.0 6.2 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3829 PF12889.7 GBG59820.1 - 0.083 12.4 0.9 0.17 11.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) KxDL PF10241.9 GBG59820.1 - 0.088 13.1 3.6 0.088 13.1 1.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 GBG59820.1 - 0.15 12.1 3.4 0.32 11.0 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CLZ PF16526.5 GBG59820.1 - 0.3 11.5 7.2 0.42 11.0 3.6 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc24 PF08286.11 GBG59820.1 - 0.33 11.2 2.5 0.86 9.9 1.6 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 GBG59820.1 - 0.34 10.2 1.5 0.47 9.8 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 GBG59820.1 - 0.41 10.0 10.2 0.15 11.4 5.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ABC_tran_CTD PF16326.5 GBG59820.1 - 0.81 10.0 4.0 1.7 8.9 3.0 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 GBG59820.1 - 1.7 8.6 15.3 0.027 14.5 8.0 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 GBG59820.1 - 2 8.8 8.0 0.19 12.0 2.8 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC2_membrane PF01061.24 GBG59821.1 - 1.3e-31 109.7 27.1 2.2e-31 108.9 27.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GBG59821.1 - 5.4e-22 78.8 0.0 9.5e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG59821.1 - 1.8e-08 34.6 0.3 0.00037 20.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 GBG59821.1 - 9.4e-06 25.0 23.8 1.4e-05 24.4 23.1 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 GBG59821.1 - 0.0023 17.4 0.1 0.01 15.3 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 GBG59821.1 - 0.025 14.5 0.0 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 GBG59821.1 - 0.038 13.7 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GBG59821.1 - 0.072 13.0 0.7 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_13 PF13166.6 GBG59821.1 - 0.11 11.1 1.1 0.32 9.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GBG59821.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 GBG59821.1 - 0.11 12.9 0.1 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG59821.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 GBG59821.1 - 0.15 11.7 0.1 16 5.1 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase T2SSE PF00437.20 GBG59821.1 - 0.2 10.7 0.1 0.42 9.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-CCHC PF00098.23 GBG59822.1 - 4e-06 26.7 4.3 8.3e-06 25.6 4.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG59822.1 - 0.016 14.9 2.1 0.038 13.7 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG59822.1 - 0.06 13.2 0.7 0.14 12.0 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle GRP PF07172.11 GBG59822.1 - 0.17 12.6 0.3 0.17 12.6 0.3 2.6 3 1 0 3 3 3 0 Glycine rich protein family DUF4419 PF14388.6 GBG59822.1 - 0.29 10.5 3.5 0.42 10.0 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) D5_N PF08706.11 GBG59822.1 - 0.85 9.9 7.4 1.4 9.2 7.4 1.4 1 1 0 1 1 1 0 D5 N terminal like DUF4407 PF14362.6 GBG59822.1 - 4.3 6.6 9.9 5 6.4 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CCHC PF00098.23 GBG59823.1 - 4e-06 26.7 4.3 8.3e-06 25.6 4.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG59823.1 - 0.016 14.9 2.1 0.038 13.7 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG59823.1 - 0.06 13.2 0.7 0.14 12.0 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle GRP PF07172.11 GBG59823.1 - 0.17 12.6 0.3 0.17 12.6 0.3 2.6 3 1 0 3 3 3 0 Glycine rich protein family DUF4419 PF14388.6 GBG59823.1 - 0.29 10.5 3.5 0.42 10.0 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) D5_N PF08706.11 GBG59823.1 - 0.85 9.9 7.4 1.4 9.2 7.4 1.4 1 1 0 1 1 1 0 D5 N terminal like DUF4407 PF14362.6 GBG59823.1 - 4.3 6.6 9.9 5 6.4 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 GBG59825.1 - 0.00012 20.7 13.6 0.00013 20.6 13.6 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein DUF572 PF04502.13 GBG59825.1 - 6.1 6.4 34.4 8.9 5.8 34.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) F-box-like PF12937.7 GBG59830.1 - 4.3e-06 26.5 0.2 1.2e-05 25.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like Polyketide_cyc PF03364.20 GBG59832.1 - 8.3e-25 87.5 1.0 1.6e-24 86.6 1.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GBG59833.1 - 2e-22 79.8 1.1 3.7e-22 78.9 1.1 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport S_4TM PF18159.1 GBG59834.1 - 5.4 6.2 7.5 6.6 5.9 7.5 1.2 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF3584 PF12128.8 GBG59835.1 - 5.7e-05 20.9 20.9 7.4e-05 20.5 20.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 GBG59835.1 - 0.24 11.4 3.3 0.7 9.9 0.9 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_15 PF13175.6 GBG59835.1 - 0.25 11.0 10.4 0.36 10.5 10.4 1.3 1 0 0 1 1 1 0 AAA ATPase domain RecG_N PF17190.4 GBG59835.1 - 0.67 10.7 16.9 0.06 14.1 10.4 2.5 2 1 1 3 3 3 0 RecG N-terminal helical domain MDMPI_N PF11716.8 GBG59835.1 - 0.78 10.4 2.8 2.6 8.7 0.6 2.4 1 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain FliS PF02561.14 GBG59835.1 - 1.2 9.5 10.8 3.1 8.1 10.7 1.8 1 1 0 1 1 1 0 Flagellar protein FliS Mga PF05043.13 GBG59835.1 - 1.3 9.7 7.6 0.23 12.1 1.5 2.6 1 1 2 3 3 3 0 Mga helix-turn-helix domain Prominin PF05478.11 GBG59835.1 - 1.9 6.4 17.4 3.6 5.4 17.4 1.5 1 1 0 1 1 1 0 Prominin SLATT_fungal PF18142.1 GBG59835.1 - 4.4 7.3 8.5 1.1 9.2 4.6 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain AAA_13 PF13166.6 GBG59835.1 - 4.9 5.7 20.3 6.6 5.2 20.3 1.1 1 0 0 1 1 1 0 AAA domain PTS_IIA PF02255.16 GBG59835.1 - 4.9 7.3 13.1 1 9.4 4.3 3.3 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit RRF PF01765.19 GBG59835.1 - 5.6 6.9 21.8 0.53 10.2 15.0 2.5 2 1 1 3 3 3 0 Ribosome recycling factor NBD_C PF17042.5 GBG59835.1 - 8.1 6.9 11.0 1.7 9.2 4.7 2.5 1 1 1 2 2 2 0 Nucleotide-binding C-terminal domain Fib_alpha PF08702.10 GBG59835.1 - 9.2 6.4 21.9 8.2 6.6 1.1 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family zf-CCHC PF00098.23 GBG59836.1 - 1.6e-05 24.7 3.8 4e-05 23.5 3.8 1.7 1 0 0 1 1 1 1 Zinc knuckle COP23 PF14218.6 GBG59836.1 - 0.019 14.7 0.2 0.038 13.7 0.2 1.5 1 0 0 1 1 1 0 Circadian oscillating protein COP23 Menin PF05053.13 GBG59836.1 - 0.1 10.9 9.8 0.13 10.6 9.8 1.2 1 0 0 1 1 1 0 Menin zf-CCHC_2 PF13696.6 GBG59836.1 - 0.21 11.5 2.7 0.4 10.6 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle XRN_M PF17846.1 GBG59836.1 - 0.92 8.4 8.6 1.5 7.7 8.6 1.4 1 0 0 1 1 1 0 Xrn1 helical domain SOBP PF15279.6 GBG59836.1 - 1.1 9.8 13.2 1.8 9.1 13.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Folliculin PF11704.8 GBG59836.1 - 3.7 7.4 6.9 13 5.6 6.9 1.9 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport GTP-bdg_M PF16360.5 GBG59837.1 - 0.0091 16.6 6.5 0.04 14.5 6.0 2.5 2 0 0 2 2 2 1 GTP-binding GTPase Middle Region Tropomyosin PF00261.20 GBG59837.1 - 0.017 14.5 36.1 0.068 12.5 36.1 1.9 1 1 0 1 1 1 0 Tropomyosin Snapin_Pallidin PF14712.6 GBG59837.1 - 0.29 11.6 16.6 0.04 14.3 2.6 2.9 2 1 1 3 3 3 0 Snapin/Pallidin Takusan PF04822.13 GBG59837.1 - 3.6 7.5 16.2 8.5 6.3 4.6 2.9 2 1 1 3 3 3 0 Takusan Macoilin PF09726.9 GBG59837.1 - 6.6 5.2 17.4 10 4.6 17.4 1.2 1 0 0 1 1 1 0 Macoilin family RVT_1 PF00078.27 GBG59838.1 - 5.8e-33 114.3 0.0 1e-32 113.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59838.1 - 2.9e-11 43.3 0.1 1.2e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59838.1 - 8e-06 25.7 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59838.1 - 1.9e-05 25.2 0.0 4.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59838.1 - 0.00089 19.8 0.0 0.0031 18.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG59838.1 - 0.04 13.7 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) ADP_ribosyl_GH PF03747.14 GBG59838.1 - 0.15 11.7 0.1 8.4 6.0 0.1 3.0 3 0 0 3 3 3 0 ADP-ribosylglycohydrolase Asp_protease PF09668.10 GBG59838.1 - 0.17 11.7 0.0 5 6.9 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease APC_u15 PF16636.5 GBG59838.1 - 8.8 6.8 6.9 28 5.2 6.9 1.9 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 RT_RNaseH PF17917.1 GBG59839.1 - 3.9e-19 68.9 0.0 8.1e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59839.1 - 1.7e-16 60.1 0.0 3.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromate_transp PF02417.15 GBG59841.1 - 1.2e-49 168.5 28.4 1.2e-25 90.4 7.3 2.3 2 0 0 2 2 2 2 Chromate transporter RT_RNaseH_2 PF17919.1 GBG59842.1 - 3.4e-28 97.6 0.0 6.5e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59842.1 - 5e-24 84.6 0.0 9.2e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59842.1 - 4.2e-14 52.4 0.1 4.2e-14 52.4 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG59842.1 - 0.063 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger BAF1_ABF1 PF04684.13 GBG59843.1 - 0.024 13.7 9.0 0.029 13.5 9.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RT_RNaseH PF17917.1 GBG59847.1 - 9.4e-21 74.1 0.0 2.5e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59847.1 - 2.2e-19 69.3 0.0 4.5e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59847.1 - 4.6e-16 58.7 1.5 1.3e-15 57.3 1.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59847.1 - 1.7e-15 57.3 0.0 4.7e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG59847.1 - 7.4e-07 29.6 0.1 1.6e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59847.1 - 6e-05 23.6 0.1 0.00013 22.6 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG59847.1 - 0.00043 20.1 0.1 0.00076 19.3 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG59847.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG59849.1 - 0.021 14.6 0.0 0.067 13.0 0.0 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG59850.1 - 6.7e-23 81.2 0.1 1.1e-22 80.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG59850.1 - 5.4e-10 39.5 0.2 1.4e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain DUF2573 PF10835.8 GBG59850.1 - 0.15 12.4 0.3 0.78 10.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2573) Ammonium_transp PF00909.21 GBG59851.1 - 5.6e-99 331.5 22.9 7.5e-99 331.1 22.9 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family PP2C PF00481.21 GBG59851.1 - 6.2e-40 137.5 0.0 9.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C CutC PF03932.14 GBG59851.1 - 0.18 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 CutC family DHR10 PF18595.1 GBG59852.1 - 0.21 11.7 0.6 0.39 10.8 0.6 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ALMT PF11744.8 GBG59853.1 - 0.042 12.7 11.6 0.057 12.3 11.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Speriolin_N PF15058.6 GBG59853.1 - 0.082 13.0 7.2 0.26 11.3 6.9 1.9 1 1 0 1 1 1 0 Speriolin N terminus Leu_zip PF15294.6 GBG59853.1 - 0.095 12.2 0.2 0.095 12.2 0.2 2.2 2 0 0 2 2 2 0 Leucine zipper TFIIA PF03153.13 GBG59853.1 - 0.23 11.4 23.6 0.28 11.1 23.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 GBG59853.1 - 0.25 9.6 14.6 0.25 9.6 14.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ZapB PF06005.12 GBG59853.1 - 1.7 9.2 13.5 6.5 7.3 1.9 3.3 3 0 0 3 3 3 0 Cell division protein ZapB Hid1 PF12722.7 GBG59853.1 - 2 6.5 5.8 2.7 6.0 5.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mob_synth_C PF06463.13 GBG59853.1 - 2.5 8.0 7.5 3.9 7.4 0.6 2.6 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C SUIM_assoc PF16619.5 GBG59853.1 - 6.6 6.9 17.3 0.27 11.3 8.7 3.1 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3306 PF11748.8 GBG59853.1 - 6.9 7.6 9.0 1.5 9.7 5.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) COX7C PF02935.16 GBG59853.1 - 7.7 6.9 10.1 0.36 11.1 0.3 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Suf PF05843.14 GBG59853.1 - 7.8 6.4 10.9 13 5.6 10.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ATG16 PF08614.11 GBG59854.1 - 0.013 15.8 2.6 0.013 15.8 2.6 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Speriolin_N PF15058.6 GBG59854.1 - 0.015 15.4 2.9 0.023 14.8 2.9 1.4 1 1 0 1 1 1 0 Speriolin N terminus Leu_zip PF15294.6 GBG59854.1 - 0.05 13.1 5.3 0.052 13.1 0.1 2.1 2 0 0 2 2 2 0 Leucine zipper Endostatin PF06482.11 GBG59854.1 - 0.32 10.4 10.1 0.36 10.2 10.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ALMT PF11744.8 GBG59854.1 - 0.76 8.5 8.5 0.93 8.2 8.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 GBG59854.1 - 1.4 6.9 5.7 1.7 6.7 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 GBG59854.1 - 1.7 8.6 27.5 2 8.3 27.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Striatin PF08232.12 GBG59854.1 - 2.1 8.9 16.1 12 6.5 16.1 1.9 1 1 0 1 1 1 0 Striatin family YABBY PF04690.13 GBG59854.1 - 2.7 8.5 0.0 2.7 8.5 0.0 2.3 2 1 0 2 2 2 0 YABBY protein PAT1 PF09770.9 GBG59854.1 - 4.2 5.5 19.9 4.7 5.3 19.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIF4E-T PF10477.9 GBG59854.1 - 5.5 5.7 17.8 6.9 5.4 17.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF3306 PF11748.8 GBG59854.1 - 6 7.8 9.4 1.2 10.1 5.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF928 PF06051.12 GBG59855.1 - 0.012 15.5 0.3 0.03 14.2 0.3 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF928) COesterase PF00135.28 GBG59855.1 - 0.042 12.7 0.2 0.053 12.4 0.2 1.3 1 0 0 1 1 1 0 Carboxylesterase family CRT10 PF08728.10 GBG59855.1 - 0.24 9.6 2.4 0.28 9.3 2.4 1.2 1 0 0 1 1 1 0 CRT10 DUF1501 PF07394.12 GBG59855.1 - 0.37 9.8 3.4 0.23 10.5 1.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1501) EHN PF06441.12 GBG59855.1 - 0.64 10.4 2.8 0.64 10.4 0.7 2.1 1 1 0 2 2 2 0 Epoxide hydrolase N terminus RVT_1 PF00078.27 GBG59856.1 - 3.3e-08 33.3 0.0 5.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59856.1 - 0.00029 20.8 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59856.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG59856.1 - 0.22 11.6 1.7 0.53 10.5 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG59857.1 - 5.9e-26 91.4 0.1 7.7e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG59858.1 - 3.6e-44 150.9 0.7 9.1e-28 97.3 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG59858.1 - 1.3e-09 38.3 0.0 4.3e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG59858.1 - 3.1e-07 30.3 0.0 1.2e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG59858.1 - 0.00025 20.8 0.0 0.00059 19.6 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG59858.1 - 0.0013 19.3 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59858.1 - 0.0017 18.9 0.0 0.0038 17.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG59858.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease ATG13 PF10033.9 GBG59860.1 - 1.1e-34 120.2 0.0 2.1e-34 119.3 0.0 1.4 1 1 0 1 1 1 1 Autophagy-related protein 13 Lung_7-TM_R PF06814.13 GBG59861.1 - 6.7e-92 307.9 17.7 9e-92 307.4 17.7 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Spo7 PF03907.13 GBG59861.1 - 0.02 14.3 0.7 0.02 14.3 0.7 1.6 2 0 0 2 2 2 0 Spo7-like protein GpcrRhopsn4 PF10192.9 GBG59861.1 - 0.039 13.3 11.7 0.061 12.7 11.7 1.3 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain CENP-F_leu_zip PF10473.9 GBG59862.1 - 0.011 15.7 4.3 0.011 15.7 4.3 2.8 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rab5-bind PF09311.11 GBG59862.1 - 0.012 15.0 2.3 0.012 15.0 2.3 2.2 2 1 0 2 2 2 0 Rabaptin-like protein TAA-Trp-ring PF15401.6 GBG59862.1 - 0.087 13.3 1.3 0.14 12.7 0.1 2.1 2 0 0 2 2 2 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin SYCE1 PF15233.6 GBG59862.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.9 2 2 1 3 3 3 0 Synaptonemal complex central element protein 1 TMF_TATA_bd PF12325.8 GBG59862.1 - 0.23 11.7 0.1 0.23 11.7 0.1 3.8 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding MbeD_MobD PF04899.12 GBG59862.1 - 0.24 11.5 4.4 0.43 10.7 0.4 3.0 3 1 0 3 3 3 0 MbeD/MobD like DUF1192 PF06698.11 GBG59862.1 - 0.37 10.9 6.4 0.4 10.8 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) FlaC_arch PF05377.11 GBG59862.1 - 0.39 11.1 5.2 6.5 7.2 0.0 3.7 3 1 0 4 4 3 0 Flagella accessory protein C (FlaC) LMBR1 PF04791.16 GBG59862.1 - 2.6 6.8 5.0 3.7 6.4 4.3 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 GBG59862.1 - 6.5 5.2 7.9 11 4.4 0.1 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family YabA PF06156.13 GBG59862.1 - 8.5 7.1 14.6 2.9 8.6 0.0 3.8 1 1 3 4 4 4 0 Initiation control protein YabA HAUS6_N PF14661.6 GBG59863.1 - 7.9e-36 123.8 0.1 1.6e-35 122.8 0.0 1.5 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus HAMP PF00672.25 GBG59863.1 - 0.02 15.2 0.1 0.056 13.8 0.1 1.8 1 0 0 1 1 1 0 HAMP domain IFT57 PF10498.9 GBG59863.1 - 0.44 9.5 1.5 21 4.0 0.0 2.4 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 DUF659 PF04937.15 GBG59867.1 - 1e-07 32.0 0.0 2.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59867.1 - 0.00051 19.8 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4173 PF13777.6 GBG59868.1 - 0.53 9.7 1.5 0.86 9.0 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Mu-like_Pro PF10123.9 GBG59868.1 - 3 7.3 9.1 5.5 6.4 9.1 1.4 1 0 0 1 1 1 0 Mu-like prophage I protein RTA1 PF04479.13 GBG59870.1 - 0.13 11.9 3.6 90 2.6 0.0 4.8 1 1 4 6 6 6 0 RTA1 like protein SH3_19 PF18597.1 GBG59870.1 - 0.19 11.6 16.9 32 4.4 0.1 6.1 6 0 0 6 6 6 0 Myosin X N-terminal SH3 domain FBA_3 PF08268.12 GBG59870.1 - 0.2 11.6 7.0 1.9 8.5 0.1 3.2 1 1 1 2 2 2 0 F-box associated domain RVT_1 PF00078.27 GBG59871.1 - 1e-34 120.0 0.0 1.8e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59871.1 - 1.1e-20 73.9 0.2 2.9e-20 72.5 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59871.1 - 1.1e-18 67.1 1.2 1.8e-18 66.4 0.5 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG59871.1 - 1.9e-12 47.1 0.0 4.8e-11 42.6 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG59871.1 - 0.002 18.3 0.0 0.0051 17.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG59871.1 - 0.0054 16.9 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG59873.1 - 5.3e-26 91.5 0.0 8.9e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59873.1 - 5.5e-11 42.4 0.0 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG59873.1 - 0.0009 19.2 0.0 0.0026 17.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59873.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG59873.1 - 0.019 15.1 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG59875.1 - 2.7e-13 49.8 0.0 6e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59875.1 - 8.4e-11 42.1 0.5 4.7e-10 39.7 0.1 2.5 2 0 0 2 2 2 1 Integrase core domain DUF1904 PF08921.11 GBG59875.1 - 0.095 13.0 0.2 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) DUF2862 PF11061.8 GBG59875.1 - 0.24 11.3 0.9 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) Fib_alpha PF08702.10 GBG59875.1 - 3.4 7.8 5.1 6.2 7.0 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.22 GBG59877.1 - 4.3e-50 167.4 0.1 5.3e-19 67.8 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG59877.1 - 5.9e-09 35.7 0.0 0.0028 17.5 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GBG59877.1 - 0.00012 21.9 0.1 0.97 9.5 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 GBG59877.1 - 0.00016 21.2 0.0 0.19 11.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GBG59877.1 - 0.00052 20.0 0.1 0.01 15.9 0.0 2.7 2 1 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 GBG59877.1 - 0.00084 19.4 0.3 0.77 9.9 0.1 3.6 2 1 1 3 3 3 1 RNA recognition motif PHM7_cyt PF14703.6 GBG59877.1 - 0.009 16.3 1.0 1.3 9.2 0.0 3.6 2 2 2 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter Spo7_2_N PF15407.6 GBG59877.1 - 0.013 15.1 0.1 0.044 13.4 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein family 7 DbpA PF03880.15 GBG59877.1 - 0.036 14.1 0.4 0.16 12.0 0.1 2.3 3 0 0 3 3 3 0 DbpA RNA binding domain Limkain-b1 PF11608.8 GBG59877.1 - 0.062 13.4 0.0 3.1 7.9 0.0 2.8 2 0 0 2 2 2 0 Limkain b1 Peptidase_M17_N PF02789.17 GBG59877.1 - 0.18 11.7 4.3 1.3 8.9 2.4 2.5 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain CDC45 PF02724.14 GBG59877.1 - 2 6.6 6.0 2.4 6.3 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG59877.1 - 2.1 7.7 12.4 3.1 7.2 12.4 1.3 1 0 0 1 1 1 0 SDA1 Myb_DNA-bind_4 PF13837.6 GBG59878.1 - 1.5e-08 34.9 2.0 7.4e-08 32.7 1.1 2.6 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG59878.1 - 0.0092 16.2 0.1 2.5 8.4 0.4 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain zinc_ribbon_11 PF11682.8 GBG59878.1 - 0.075 13.1 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon MADF_DNA_bdg PF10545.9 GBG59878.1 - 0.076 13.3 2.4 0.11 12.8 1.4 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG59878.1 - 0.095 12.8 6.5 0.12 12.4 5.0 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG59879.1 - 4.8e-27 94.6 0.0 8.3e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG59879.1 - 9.6e-14 51.5 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG59879.1 - 4.6e-06 26.4 0.0 0.0032 17.1 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain F-box-like PF12937.7 GBG59881.1 - 1.7e-05 24.6 0.2 4e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG59881.1 - 0.093 12.6 0.3 0.23 11.4 0.3 1.7 1 0 0 1 1 1 0 F-box domain T4SS PF07996.11 GBG59882.1 - 1.7 9.0 9.8 3.5 8.0 9.8 1.5 1 1 0 1 1 1 0 Type IV secretion system proteins Nucleoporin_FG PF13634.6 GBG59883.1 - 0.006 17.4 52.7 0.0097 16.7 18.0 3.9 2 1 1 3 3 3 2 Nucleoporin FG repeat region SDA1 PF05285.12 GBG59883.1 - 0.028 13.9 21.5 0.055 12.9 21.5 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG59883.1 - 0.15 10.3 16.5 0.21 9.8 16.5 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG59883.1 - 0.41 9.4 7.6 0.7 8.6 7.6 1.3 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 GBG59883.1 - 1.3 8.3 16.6 2.6 7.4 16.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC27 PF09507.10 GBG59883.1 - 1.6 8.1 14.3 3.3 7.0 14.3 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NPR3 PF03666.13 GBG59883.1 - 1.8 7.2 7.7 2.7 6.7 7.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 GBG59883.1 - 6.9 4.8 15.0 10 4.2 15.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 GBG59883.1 - 8.2 6.2 13.8 17 5.2 13.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.12 GBG59884.1 - 0.0026 17.3 13.9 0.0032 17.0 13.9 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GBG59884.1 - 0.0035 16.8 14.0 0.0042 16.5 14.0 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 GBG59884.1 - 0.0037 15.6 12.1 0.0044 15.3 12.1 1.2 1 0 0 1 1 1 1 Nop14-like family CobT PF06213.12 GBG59884.1 - 0.0071 15.8 14.4 0.0071 15.8 14.4 1.6 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 GBG59884.1 - 0.047 12.4 3.4 0.048 12.4 3.4 1.2 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 GBG59884.1 - 0.067 12.1 0.1 0.087 11.7 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4746 PF15928.5 GBG59884.1 - 0.13 11.6 14.7 0.19 11.1 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 GBG59884.1 - 0.22 10.3 2.7 0.24 10.1 2.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 GBG59884.1 - 0.25 9.6 11.6 0.28 9.4 11.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 GBG59884.1 - 0.26 10.2 0.9 0.24 10.4 0.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 GBG59884.1 - 0.3 10.3 1.4 0.33 10.1 1.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 GBG59884.1 - 0.31 10.5 1.0 0.42 10.1 1.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 CPSF100_C PF13299.6 GBG59884.1 - 0.66 10.1 9.7 0.13 12.5 5.8 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PPL5 PF18168.1 GBG59884.1 - 0.82 8.9 3.2 1.3 8.3 3.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF2151 PF10221.9 GBG59884.1 - 0.96 8.0 3.3 1.3 7.6 3.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RNA_pol_Rpc4 PF05132.14 GBG59884.1 - 2.5 8.5 6.9 0.47 10.9 3.0 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 V_ATPase_I PF01496.19 GBG59884.1 - 2.7 5.8 6.0 3.4 5.5 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 GBG59884.1 - 4.8 6.9 16.2 0.38 10.5 10.3 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Nucleoporin_FG PF13634.6 GBG59885.1 - 0.018 15.9 66.9 0.098 13.5 24.0 3.7 2 1 1 3 3 3 0 Nucleoporin FG repeat region Tmemb_cc2 PF10267.9 GBG59885.1 - 0.069 12.3 1.2 3.5 6.7 0.2 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein CCDC-167 PF15188.6 GBG59885.1 - 1.1 9.7 4.2 4.8 7.6 0.3 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 APG6 PF04111.12 GBG59887.1 - 1.3e-67 227.2 0.0 2.3e-67 226.4 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 GBG59887.1 - 2e-24 86.6 19.6 3e-24 86.1 19.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region ThylakoidFormat PF11264.8 GBG59887.1 - 0.11 12.2 1.2 0.18 11.5 1.2 1.2 1 0 0 1 1 1 0 Thylakoid formation protein DUF4407 PF14362.6 GBG59887.1 - 0.11 11.8 4.0 0.17 11.2 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 GBG59887.1 - 0.12 13.0 3.2 0.11 13.1 1.7 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 GBG59887.1 - 0.15 12.1 4.9 6.8 6.9 4.9 2.6 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.8 GBG59887.1 - 1.8 8.7 8.2 13 5.8 3.7 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding BRD4_CDT PF17105.5 GBG59887.1 - 2 8.1 6.2 0.55 9.9 2.6 1.9 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 RT_RNaseH_2 PF17919.1 GBG59888.1 - 1.3e-46 156.8 0.0 2.2e-25 88.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59888.1 - 6.6e-35 119.6 0.0 7.1e-22 77.7 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59888.1 - 8.6e-22 77.7 0.0 2.4e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59888.1 - 1.8e-13 50.3 0.3 6.2e-13 48.6 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59888.1 - 5.4e-09 36.3 0.0 2e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG59888.1 - 6.1e-06 26.8 0.0 2.3e-05 24.9 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG59888.1 - 1.3e-05 25.4 15.1 0.052 13.8 1.6 5.9 4 1 1 5 5 5 2 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG59888.1 - 1.5e-05 25.4 0.1 9.2e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59888.1 - 0.00015 21.5 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59888.1 - 0.0037 17.0 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Baculo_PEP_C PF04513.12 GBG59888.1 - 1.9 8.5 6.5 0.93 9.5 1.8 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RT_RNaseH_2 PF17919.1 GBG59889.1 - 2.3e-19 69.3 0.0 4.7e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59889.1 - 5.9e-11 42.6 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG59889.1 - 0.00022 21.4 0.6 0.0072 16.6 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG59890.1 - 2.5e-55 184.7 0.5 7.7e-29 99.7 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59890.1 - 8e-40 135.4 0.3 3.7e-25 88.3 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59890.1 - 3.6e-37 128.0 1.0 3.5e-24 85.5 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG59890.1 - 1.1e-15 57.5 0.0 3.5e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59890.1 - 7.3e-12 45.5 0.2 1.8e-11 44.3 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain DUF5095 PF17016.5 GBG59890.1 - 0.006 16.3 2.8 1.3 8.7 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5095) TOBE_2 PF08402.10 GBG59890.1 - 0.035 14.3 0.3 26 5.0 0.0 3.5 3 0 0 3 3 3 0 TOBE domain zf-H2C2 PF09337.10 GBG59890.1 - 0.061 13.5 0.0 0.21 11.8 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger DUF2862 PF11061.8 GBG59890.1 - 0.098 12.5 0.1 0.3 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) AKAP2_C PF15304.6 GBG59890.1 - 3.2 7.0 6.6 18 4.5 3.8 2.6 3 0 0 3 3 3 0 A-kinase anchor protein 2 C-terminus Nucleoporin_FG PF13634.6 GBG59891.1 - 0.14 13.0 24.7 1.8 9.5 24.1 2.3 1 1 1 2 2 2 0 Nucleoporin FG repeat region RXLR PF16810.5 GBG59892.1 - 0.043 14.3 1.7 0.071 13.5 1.7 1.6 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity FANCM-MHF_bd PF16783.5 GBG59892.1 - 0.31 11.1 5.1 0.093 12.8 1.3 1.9 1 1 1 2 2 2 0 FANCM to MHF binding domain PAS PF00989.25 GBG59892.1 - 0.49 10.4 2.4 0.7 9.9 0.5 2.0 1 1 1 2 2 2 0 PAS fold GNAT_acetyltr_2 PF13718.6 GBG59892.1 - 2.4 7.5 5.9 13 5.1 0.1 2.2 1 1 0 2 2 2 0 GNAT acetyltransferase 2 TFIIA PF03153.13 GBG59892.1 - 2.9 7.8 14.0 3.6 7.5 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 GBG59894.1 - 3.1e-17 62.0 31.0 0.0015 18.8 0.2 5.9 6 0 0 6 6 6 5 Zinc finger, C2H2 type RT_RNaseH PF17917.1 GBG59894.1 - 2.4e-16 59.9 0.2 5.2e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2_2 PF13465.6 GBG59894.1 - 6.7e-14 51.6 26.7 0.00028 21.2 1.4 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GBG59894.1 - 7.8e-11 41.9 25.0 0.01 16.6 1.5 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger RT_RNaseH_2 PF17919.1 GBG59894.1 - 8.6e-11 41.8 0.1 3e-10 40.0 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-C2H2_8 PF15909.5 GBG59894.1 - 0.00023 21.4 6.1 0.0018 18.5 3.1 2.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 GBG59894.1 - 0.0024 17.8 19.0 1.4 9.0 1.7 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GBG59894.1 - 0.033 14.1 7.6 1.9 8.5 0.1 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 GBG59894.1 - 1.8 9.3 11.8 35 5.1 0.0 4.8 2 2 3 5 5 5 0 FOXP coiled-coil domain zf-TRAF PF02176.18 GBG59894.1 - 4.3 8.1 12.3 1.7 9.4 0.5 3.3 1 1 3 4 4 4 0 TRAF-type zinc finger zf-C2H2 PF00096.26 GBG59896.1 - 1.7e-17 62.8 31.0 0.0014 19.0 0.2 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type RT_RNaseH PF17917.1 GBG59896.1 - 2e-16 60.1 0.2 4.6e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2_2 PF13465.6 GBG59896.1 - 3.7e-14 52.4 26.7 0.00025 21.3 1.4 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GBG59896.1 - 4.3e-11 42.7 25.0 0.009 16.8 1.5 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger RT_RNaseH_2 PF17919.1 GBG59896.1 - 7.1e-11 42.0 0.1 2.6e-10 40.2 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-C2H2_8 PF15909.5 GBG59896.1 - 0.00017 21.8 6.1 0.0017 18.6 3.2 2.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 GBG59896.1 - 0.0015 18.5 19.0 1.2 9.2 1.7 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GBG59896.1 - 0.022 14.7 7.6 1.7 8.6 0.1 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 GBG59896.1 - 1.1 9.9 11.5 31 5.3 0.0 4.7 2 2 3 5 5 5 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 GBG59896.1 - 1.4 9.2 6.0 8.4 6.8 0.1 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.18 GBG59896.1 - 2.9 8.6 12.2 1.5 9.6 0.5 3.3 1 1 3 4 4 4 0 TRAF-type zinc finger LIM_bind PF01803.16 GBG59898.1 - 0.0003 20.4 0.0 0.0003 20.4 0.0 6.0 2 1 1 3 3 3 1 LIM-domain binding protein RVP_2 PF08284.11 GBG59898.1 - 0.0035 17.1 0.0 0.065 13.0 0.0 2.3 1 1 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG59899.1 - 0.00073 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59900.1 - 2.6e-31 107.6 0.1 7.1e-31 106.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59900.1 - 1.4e-23 83.2 0.0 3.6e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59900.1 - 2.8e-22 79.3 0.1 1.7e-18 66.9 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG59900.1 - 0.075 13.6 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59900.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease FAM199X PF15814.5 GBG59900.1 - 5.7 5.9 6.0 9.8 5.1 6.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X LIM_bind PF01803.16 GBG59901.1 - 1.6e-10 41.0 0.0 1.6e-10 41.0 0.0 3.3 3 0 0 3 3 2 1 LIM-domain binding protein Neur_chan_memb PF02932.16 GBG59901.1 - 0.00011 22.4 22.2 0.0039 17.3 5.3 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Endostatin PF06482.11 GBG59901.1 - 0.00028 20.5 31.6 0.028 13.9 7.7 2.1 2 0 0 2 2 2 2 Collagenase NC10 and Endostatin Exonuc_VII_L PF02601.15 GBG59901.1 - 0.00039 20.1 22.3 0.012 15.2 5.8 2.2 2 0 0 2 2 2 2 Exonuclease VII, large subunit Velvet PF11754.8 GBG59901.1 - 0.0018 18.3 34.1 0.0024 17.8 12.9 2.2 2 0 0 2 2 2 1 Velvet factor BAF1_ABF1 PF04684.13 GBG59901.1 - 0.0023 17.1 18.9 0.042 12.9 4.7 2.1 2 0 0 2 2 2 2 BAF1 / ABF1 chromatin reorganising factor TCP PF03634.13 GBG59901.1 - 0.0043 17.6 25.4 0.064 13.8 8.5 2.4 2 0 0 2 2 2 2 TCP family transcription factor Pex14_N PF04695.13 GBG59901.1 - 0.0043 17.7 16.5 0.0043 17.7 16.5 2.7 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region EIF4E-T PF10477.9 GBG59901.1 - 0.0044 15.9 13.6 0.0044 15.9 13.6 2.1 2 0 0 2 2 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PAT1 PF09770.9 GBG59901.1 - 0.0069 14.7 51.8 0.02 13.2 18.9 2.1 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 TT_ORF1 PF02956.14 GBG59901.1 - 0.0085 14.8 12.0 0.029 13.0 2.6 2.1 2 0 0 2 2 2 2 TT viral orf 1 SID-1_RNA_chan PF13965.6 GBG59901.1 - 0.013 14.0 9.1 0.053 11.9 0.4 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 MecA PF05389.12 GBG59901.1 - 0.013 15.1 14.0 0.095 12.3 2.5 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF719 PF05334.13 GBG59901.1 - 0.015 15.5 20.7 0.14 12.4 7.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Draxin PF15550.6 GBG59901.1 - 0.018 15.0 19.4 0.098 12.5 5.3 2.2 2 0 0 2 2 2 0 Draxin Presenilin PF01080.17 GBG59901.1 - 0.021 13.6 34.6 0.081 11.7 13.8 2.2 2 0 0 2 2 2 0 Presenilin EOS1 PF12326.8 GBG59901.1 - 0.025 14.5 11.4 0.74 9.7 1.2 2.4 2 0 0 2 2 2 0 N-glycosylation protein CCDC53 PF10152.9 GBG59901.1 - 0.026 15.0 25.3 0.4 11.1 10.7 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CPSF100_C PF13299.6 GBG59901.1 - 0.04 14.1 22.9 0.52 10.5 8.7 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 GBG59901.1 - 0.055 12.7 25.6 0.12 11.5 7.9 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter FAM60A PF15396.6 GBG59901.1 - 0.057 13.4 21.8 0.84 9.6 6.4 2.2 2 0 0 2 2 2 0 Protein Family FAM60A RR_TM4-6 PF06459.12 GBG59901.1 - 0.059 13.2 28.2 0.38 10.5 11.0 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BORG_CEP PF14957.6 GBG59901.1 - 0.067 14.4 22.3 0.47 11.6 7.9 2.5 2 0 0 2 2 2 0 Cdc42 effector DUF4407 PF14362.6 GBG59901.1 - 0.096 12.0 24.9 0.026 13.9 7.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 GBG59901.1 - 0.11 11.5 36.9 0.06 12.3 14.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.6 GBG59901.1 - 0.11 10.4 65.6 0.024 12.6 29.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) SAPS PF04499.15 GBG59901.1 - 0.15 10.9 17.7 0.16 10.8 4.9 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CCSAP PF15748.5 GBG59901.1 - 0.15 12.2 32.4 0.21 11.7 11.5 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SLC12 PF03522.15 GBG59901.1 - 0.17 10.9 30.4 0.053 12.5 9.0 2.1 2 0 0 2 2 2 0 Solute carrier family 12 FAM76 PF16046.5 GBG59901.1 - 0.2 11.0 35.2 0.2 11.0 13.5 2.1 2 0 0 2 2 2 0 FAM76 protein DUF3295 PF11702.8 GBG59901.1 - 0.24 10.7 29.7 0.063 12.6 9.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) DUF572 PF04502.13 GBG59901.1 - 0.32 10.6 22.2 0.14 11.7 5.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) SMYLE_N PF18615.1 GBG59901.1 - 0.32 10.5 19.6 0.37 10.3 3.0 2.3 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF4045 PF13254.6 GBG59901.1 - 0.4 10.3 23.7 0.36 10.4 6.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) MMR1 PF08505.10 GBG59901.1 - 0.57 10.4 41.2 1.1 9.5 15.2 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF4050 PF13259.6 GBG59901.1 - 0.59 10.4 23.9 0.12 12.7 5.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) SpoIIP PF07454.11 GBG59901.1 - 0.72 9.3 31.1 0.13 11.7 11.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SpoVR PF04293.13 GBG59901.1 - 0.88 8.2 21.5 0.68 8.6 3.5 2.1 2 0 0 2 2 2 0 SpoVR like protein PTPRCAP PF15713.5 GBG59901.1 - 1 9.7 31.1 2.8 8.2 7.2 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PPP4R2 PF09184.11 GBG59901.1 - 1.1 8.8 11.2 1.5 8.3 2.6 2.2 2 0 0 2 2 2 0 PPP4R2 DUF4228 PF14009.6 GBG59901.1 - 1.1 9.6 15.2 4.3 7.7 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) LAP1C PF05609.12 GBG59901.1 - 1.2 8.2 31.4 2.2 7.3 11.6 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) RNA_pol_Rpc4 PF05132.14 GBG59901.1 - 1.3 9.4 25.7 1.5 9.3 3.1 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 CDK5_activator PF03261.15 GBG59901.1 - 1.5 8.3 25.1 0.36 10.3 5.2 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein DUF4471 PF14740.6 GBG59901.1 - 2 7.6 21.0 0.98 8.6 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DAG_kinase_N PF14513.6 GBG59901.1 - 2.1 8.5 28.7 0.52 10.5 8.9 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Plasmodium_Vir PF05795.11 GBG59901.1 - 2.2 7.6 15.5 0.53 9.6 5.1 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein AUX_IAA PF02309.16 GBG59901.1 - 2.4 8.0 16.9 0.19 11.6 1.4 2.2 2 0 0 2 2 2 0 AUX/IAA family GREB1 PF15782.5 GBG59901.1 - 2.4 5.2 34.9 0.051 10.7 10.4 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Phage_GPO PF05929.11 GBG59901.1 - 2.5 7.7 29.3 0.37 10.4 8.7 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Dynactin_p62 PF05502.13 GBG59901.1 - 2.7 6.7 23.7 0.73 8.5 4.2 2.1 2 0 0 2 2 2 0 Dynactin p62 family DUF966 PF06136.13 GBG59901.1 - 3.2 7.4 23.7 0.76 9.4 7.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Phage_GPD PF05954.11 GBG59901.1 - 4 6.6 31.6 2.4 7.3 15.1 2.1 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) Raftlin PF15250.6 GBG59901.1 - 4.7 5.8 28.5 3.9 6.1 12.4 2.1 2 0 0 2 2 2 0 Raftlin Baculo_PP31 PF05311.11 GBG59901.1 - 5.2 6.5 27.9 0.32 10.5 7.6 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) CobT PF06213.12 GBG59901.1 - 5.4 6.3 41.1 0.093 12.1 16.7 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Serinc PF03348.15 GBG59901.1 - 6 5.7 23.3 2.2 7.1 7.3 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF3464 PF11947.8 GBG59901.1 - 6.2 6.6 31.3 0.47 10.2 4.8 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 STAC2_u1 PF16664.5 GBG59901.1 - 9 6.8 28.1 0.062 13.8 7.3 2.8 2 1 0 2 2 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 EPL1 PF10513.9 GBG59901.1 - 9.3 6.6 38.0 1.2 9.5 13.5 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Kinesin PF00225.23 GBG59903.1 - 8.5e-107 356.9 0.0 1.2e-106 356.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG59903.1 - 1.6e-57 193.6 0.0 2.9e-57 192.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Autotransporter PF03797.19 GBG59903.1 - 0.045 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Autotransporter beta-domain SPATA1_C PF15743.5 GBG59903.1 - 0.049 13.7 8.2 0.082 13.0 8.2 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus EFTUD2 PF16004.5 GBG59903.1 - 3.5 8.2 6.0 1.6 9.3 0.1 2.4 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus RT_RNaseH_2 PF17919.1 GBG59904.1 - 5e-22 77.8 0.0 8.5e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59904.1 - 7.2e-22 77.7 0.0 1.3e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59904.1 - 2.9e-17 62.5 0.4 7e-17 61.3 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG59904.1 - 5.5e-10 39.1 0.0 1.9e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG59904.1 - 0.019 14.1 0.0 0.038 13.1 0.0 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 CRISPR_Cse2 PF09485.10 GBG59904.1 - 4.3 7.9 5.8 14 6.2 0.1 2.8 3 0 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) YL1 PF05764.13 GBG59905.1 - 0.0013 18.9 7.6 0.0016 18.6 7.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 GBG59905.1 - 0.021 13.1 7.8 0.023 13.0 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein SARAF PF06682.12 GBG59905.1 - 0.08 12.6 4.0 0.087 12.5 4.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DNA_pol_phi PF04931.13 GBG59905.1 - 0.13 10.3 11.4 0.14 10.2 11.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG59905.1 - 0.2 9.8 9.4 0.21 9.8 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 GBG59905.1 - 0.5 10.2 4.7 0.51 10.2 4.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region IFT57 PF10498.9 GBG59905.1 - 0.87 8.5 3.2 0.95 8.4 3.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SDA1 PF05285.12 GBG59905.1 - 0.93 8.9 9.5 1 8.7 9.5 1.1 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 GBG59905.1 - 1.2 8.2 3.4 1.3 8.2 3.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3402 PF11882.8 GBG59905.1 - 3.8 6.5 4.4 4.4 6.3 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) RRN3 PF05327.11 GBG59905.1 - 7.7 4.9 7.3 8.5 4.8 7.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 GBG59905.1 - 9.3 5.5 9.4 12 5.2 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein RT_RNaseH PF17917.1 GBG59906.1 - 2.4e-30 104.9 0.1 3.9e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59906.1 - 8.2e-29 99.6 0.0 1.6e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59906.1 - 4.1e-14 52.4 0.2 8.7e-14 51.4 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG59906.1 - 1.2e-11 44.9 0.0 3.5e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG59908.1 - 9.3e-31 105.8 0.0 2.1e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59908.1 - 7.5e-30 104.1 0.1 1.3e-29 103.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59908.1 - 2.1e-17 63.3 0.0 4.4e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59908.1 - 8e-14 51.9 0.0 1.8e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG59908.1 - 1.3e-05 25.7 0.0 3.9e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG59908.1 - 0.0011 19.1 0.2 0.0025 17.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG59908.1 - 0.0017 18.1 0.2 0.0062 16.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Asp_protease_2 PF13650.6 GBG59908.1 - 0.0044 17.6 0.0 0.0091 16.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG59908.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG59908.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG59909.1 - 3.5e-27 95.4 0.0 6.3e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59909.1 - 6.4e-27 93.5 0.0 1.3e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59909.1 - 1e-19 70.7 0.0 2.5e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59909.1 - 2.6e-14 53.4 0.0 5.3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG59910.1 - 3.6e-51 173.8 0.4 2e-26 92.9 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59910.1 - 1.9e-44 150.2 4.3 4.3e-28 97.7 0.2 3.6 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59910.1 - 3.9e-39 132.7 1.3 9.2e-30 102.6 0.0 3.5 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59910.1 - 1.5e-15 57.0 0.0 3.4e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG59910.1 - 2.7e-09 36.9 0.0 1.2e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59910.1 - 1.1e-08 35.6 0.0 3.3e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59910.1 - 7.1e-08 32.9 0.0 4.4e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG59910.1 - 0.00016 21.4 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease CDH1_2_SANT_HL1 PF18375.1 GBG59910.1 - 0.065 13.9 0.9 4 8.2 0.0 3.8 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 Retrotrans_gag PF03732.17 GBG59910.1 - 0.087 13.1 0.0 0.087 13.1 0.0 5.2 5 0 0 5 5 5 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG59911.1 - 2.4e-29 102.4 0.1 5.3e-29 101.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG59911.1 - 0.00034 20.8 4.7 0.015 15.6 0.0 4.0 4 0 0 4 4 4 2 Retrotransposon gag protein CLZ PF16526.5 GBG59911.1 - 0.2 12.0 4.2 23 5.4 0.3 4.0 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GPS2_interact PF15784.5 GBG59911.1 - 0.34 11.4 2.4 5 7.6 0.3 3.5 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain RVT_1 PF00078.27 GBG59915.1 - 3.2e-32 111.8 0.1 7.5e-32 110.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59915.1 - 2.1e-22 79.4 0.0 4.9e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59915.1 - 2.7e-16 59.4 0.6 7.4e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG59915.1 - 1.1e-12 47.9 0.0 3.5e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG59915.1 - 2.7e-05 24.3 0.0 6.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Transgly PF00912.22 GBG59916.1 - 3.4e-55 186.3 0.0 5.9e-55 185.5 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 GBG59916.1 - 8.6e-38 130.3 0.0 1.5e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain Csa1 PF06023.12 GBG59916.1 - 0.17 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 HEAT_2 PF13646.6 GBG59918.1 - 2.3e-09 37.5 0.4 0.0017 18.7 0.0 3.1 1 1 2 3 3 3 3 HEAT repeats Fes1 PF08609.10 GBG59918.1 - 1.5e-08 35.4 1.0 1.5e-08 35.4 1.0 2.3 3 0 0 3 3 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 GBG59918.1 - 2.4e-08 33.5 0.2 0.028 14.7 0.1 4.4 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.23 GBG59918.1 - 1.4e-05 24.9 0.2 1.4 9.0 0.0 4.3 5 0 0 5 5 4 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 GBG59918.1 - 0.00011 22.3 0.2 0.055 13.5 0.0 3.2 1 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 GBG59918.1 - 0.00016 21.8 0.0 0.15 12.2 0.0 2.9 2 1 1 3 3 3 2 V-ATPase subunit H SIL1 PF16782.5 GBG59918.1 - 0.00075 18.8 0.0 0.0015 17.8 0.0 1.4 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 DUF913 PF06025.12 GBG59918.1 - 0.0016 17.5 0.1 0.0045 16.0 0.0 1.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) Atx10homo_assoc PF09759.9 GBG59918.1 - 0.0023 17.9 0.3 0.031 14.3 0.0 2.5 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 GBG59918.1 - 0.0029 18.1 3.2 0.98 10.0 0.0 3.5 3 2 1 4 4 4 2 HEAT-like repeat Adaptin_N PF01602.20 GBG59918.1 - 0.0043 15.7 0.0 0.05 12.2 0.0 2.1 1 1 2 3 3 3 2 Adaptin N terminal region MMS19_N PF14500.6 GBG59918.1 - 0.0062 16.2 0.1 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II GP67 PF17634.2 GBG59918.1 - 0.01 16.3 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 1 Gene product 67 RICTOR_N PF14664.6 GBG59918.1 - 0.026 13.5 0.0 0.12 11.3 0.0 1.8 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term CLASP_N PF12348.8 GBG59918.1 - 0.095 12.2 0.1 12 5.3 0.0 2.6 1 1 0 2 2 2 0 CLASP N terminal Gcn1_N PF12074.8 GBG59918.1 - 0.15 11.3 1.3 1.9 7.7 0.0 2.8 2 1 1 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal RT_RNaseH_2 PF17919.1 GBG59921.1 - 2.4e-23 82.0 0.0 7.8e-23 80.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59921.1 - 2e-21 76.3 0.0 4.9e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59921.1 - 1.4e-18 66.7 0.2 3.7e-18 65.4 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG59921.1 - 7.9e-16 58.5 0.1 2e-07 31.6 0.0 2.9 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG59921.1 - 5.6e-15 55.7 0.0 2.9e-06 27.7 0.0 2.9 3 0 0 3 3 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59921.1 - 5.1e-12 45.7 0.0 1.5e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease rve PF00665.26 GBG59921.1 - 5.3e-09 36.3 0.0 2.8e-08 34.0 0.0 2.3 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG59921.1 - 2.1e-07 30.8 0.0 0.008 16.0 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease DUF1758 PF05585.12 GBG59921.1 - 0.0012 18.6 0.1 0.081 12.7 0.0 2.4 2 0 0 2 2 2 1 Putative peptidase (DUF1758) DUF4187 PF13821.6 GBG59921.1 - 0.047 13.5 0.2 0.15 11.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG59921.1 - 0.067 13.5 0.8 0.28 11.5 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG59921.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger WRC PF08879.10 GBG59922.1 - 1e-17 63.5 11.0 1e-17 63.5 11.0 1.8 2 0 0 2 2 2 1 WRC Dimer_Tnp_hAT PF05699.14 GBG59923.1 - 0.039 13.7 0.2 0.091 12.6 0.2 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region NHase_alpha PF02979.16 GBG59923.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain Mobilization_B PF17511.2 GBG59924.1 - 0.48 10.8 1.5 0.83 10.0 1.5 1.3 1 0 0 1 1 1 0 Mobilization protein B DsrH PF04077.12 GBG59925.1 - 3.9e-09 36.5 19.4 10 6.3 0.1 13.2 5 3 9 16 16 16 4 DsrH like protein DUF4027 PF13219.6 GBG59925.1 - 0.027 14.3 1.9 4.5 7.2 0.0 5.4 6 0 0 6 6 6 0 Protein of unknown function (DUF4027) MinC_N PF05209.13 GBG59925.1 - 0.53 10.3 3.7 2.5e+02 1.7 0.0 5.6 5 2 3 8 8 8 0 Septum formation inhibitor MinC, N-terminal domain DUF659 PF04937.15 GBG59926.1 - 1.9e-33 115.5 0.1 3e-33 114.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG59926.1 - 4.9e-11 42.3 0.1 1.2e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ribosomal_S28e PF01200.18 GBG59926.1 - 0.088 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S28e RVP_2 PF08284.11 GBG59927.1 - 4.4e-08 33.0 0.0 9.6e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG59927.1 - 0.00013 22.5 0.0 0.00028 21.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59927.1 - 0.00096 19.7 0.0 0.0028 18.2 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG59927.1 - 0.0067 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) HCO3_cotransp PF00955.21 GBG59928.1 - 6.4e-62 210.0 4.4 4.4e-34 118.2 0.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family zf-CCHC_6 PF15288.6 GBG59928.1 - 0.24 11.3 2.0 0.6 10.0 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG59928.1 - 0.33 11.1 4.1 0.75 10.0 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG59930.1 - 5.4e-23 81.3 0.0 1.2e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59930.1 - 7.4e-23 80.5 0.0 1.7e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59930.1 - 9.5e-23 80.9 0.0 2.5e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG59930.1 - 3.1e-07 30.3 0.0 6.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG59930.1 - 5e-07 29.9 0.0 1.5e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG59930.1 - 9.7e-06 26.1 0.0 2.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59930.1 - 0.0017 18.8 0.0 0.0048 17.4 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG59930.1 - 0.072 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG59930.1 - 0.12 12.7 0.0 0.45 10.8 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein AMP-binding_C_2 PF14535.6 GBG59930.1 - 0.2 12.0 0.0 0.6 10.4 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Chromo PF00385.24 GBG59931.1 - 0.017 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG59932.1 - 4.9e-26 90.7 0.0 1.1e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59932.1 - 9.3e-26 90.7 0.1 1.6e-25 89.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59932.1 - 3.4e-24 85.2 0.0 2.1e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG59932.1 - 0.043 14.0 0.1 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain RVT_1 PF00078.27 GBG59934.1 - 7.2e-08 32.2 0.9 1.2e-07 31.5 0.9 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59935.1 - 1.3e-23 83.2 0.0 2.9e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59935.1 - 8.1e-23 80.4 0.0 1.9e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59935.1 - 1.8e-19 69.6 1.5 4.8e-19 68.2 1.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG59935.1 - 3.9e-07 30.5 0.0 7.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59935.1 - 8.8e-06 26.3 0.1 1.7e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG59935.1 - 0.0009 19.0 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG59935.1 - 0.038 14.2 0.2 0.099 12.9 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 GBG59935.1 - 0.04 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG59938.1 - 2.7e-06 27.9 0.0 5.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG59938.1 - 3.9e-06 27.0 0.0 7.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG59938.1 - 0.00077 20.1 0.0 0.0021 18.7 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG59938.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59938.1 - 0.082 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DIL PF01843.19 GBG59939.1 - 2.1e-24 85.8 0.1 2.1e-24 85.8 0.1 2.2 2 0 0 2 2 2 1 DIL domain Retrotrans_gag PF03732.17 GBG59939.1 - 0.00099 19.3 1.3 0.0078 16.5 0.3 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG59939.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain CENP-K PF11802.8 GBG59939.1 - 0.44 10.1 3.5 0.77 9.3 3.5 1.4 1 0 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 GBG59939.1 - 0.97 9.4 11.1 1.6 8.7 11.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CREPT PF16566.5 GBG59939.1 - 2 8.6 7.2 6.5 6.9 2.1 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CobT PF06213.12 GBG59940.1 - 5.9 6.2 20.9 7 5.9 20.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4337 PF14235.6 GBG59940.1 - 7.7 6.6 11.5 8.1 6.5 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3487 PF11990.8 GBG59942.1 - 7.5 6.5 6.9 12 5.8 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) NAPRTase_C PF17956.1 GBG59945.1 - 0.0089 16.4 5.7 12 6.4 1.3 3.2 3 0 0 3 3 3 2 Nicotinate phosphoribosyltransferase C-terminal domain Use1 PF09753.9 GBG59945.1 - 0.53 10.0 11.4 0.63 9.7 10.1 1.6 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF4192 PF13830.6 GBG59945.1 - 0.74 9.8 13.8 0.98 9.4 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) RNR_Alpha PF17975.1 GBG59945.1 - 2.6 8.6 4.6 19 5.8 0.1 2.4 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain RVT_1 PF00078.27 GBG59946.1 - 6.4e-30 104.3 0.0 9.7e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59946.1 - 1.7e-25 89.0 0.0 4.1e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59946.1 - 1.9e-20 73.1 0.0 4.2e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG59946.1 - 5.5e-06 26.9 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59946.1 - 4.1e-05 24.1 0.0 7.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59946.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59946.1 - 0.00098 18.9 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease HNH_3 PF13392.6 GBG59946.1 - 0.0088 15.8 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Chromo PF00385.24 GBG59946.1 - 0.031 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain APG17 PF04108.12 GBG59946.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 RVT_1 PF00078.27 GBG59948.1 - 2.5e-54 184.1 0.9 1.3e-26 93.5 0.1 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59948.1 - 1.7e-32 111.4 0.0 2.6e-24 85.2 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Myosin_head PF00063.21 GBG59948.1 - 4.5e-28 97.9 0.1 4.5e-28 97.9 0.1 1.5 2 0 0 2 2 1 1 Myosin head (motor domain) RT_RNaseH PF17917.1 GBG59948.1 - 2.8e-23 82.2 0.0 1.7e-22 79.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG59948.1 - 1.1e-07 32.4 0.0 5.4e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59948.1 - 2.3e-07 31.3 0.0 6.9e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59948.1 - 3.5e-06 26.8 0.0 7.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG59948.1 - 1.3e-05 25.4 0.0 4.2e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG59948.1 - 3.5e-05 23.6 0.0 7.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease IQ PF00612.27 GBG59948.1 - 0.00037 20.0 4.8 0.094 12.6 0.1 4.8 4 0 0 4 4 4 1 IQ calmodulin-binding motif Retrotrans_gag PF03732.17 GBG59948.1 - 0.0039 17.4 0.0 0.0039 17.4 0.0 3.9 4 0 0 4 4 2 1 Retrotransposon gag protein ZapB PF06005.12 GBG59948.1 - 0.07 13.6 0.1 0.07 13.6 0.1 8.3 7 2 0 7 7 5 0 Cell division protein ZapB RT_RNaseH_2 PF17919.1 GBG59949.1 - 3.6e-23 81.5 0.0 7.3e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59949.1 - 9.2e-20 70.9 0.0 4.8e-19 68.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG59949.1 - 0.0012 19.3 0.0 0.003 18.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG59949.1 - 0.0028 18.3 0.0 0.0066 17.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG59949.1 - 0.0075 16.5 0.5 0.024 14.9 0.2 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein RVP PF00077.20 GBG59949.1 - 0.013 15.8 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG59949.1 - 0.032 14.0 0.1 0.084 12.7 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG59949.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG59950.1 - 1.7e-18 66.8 0.0 3e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG59950.1 - 2e-10 40.6 0.0 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG59950.1 - 0.15 10.3 9.2 0.19 9.9 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG59950.1 - 0.23 11.7 11.2 0.53 10.6 11.2 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG59950.1 - 0.53 8.5 9.1 0.72 8.1 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG59950.1 - 0.57 9.6 11.1 0.87 9.0 11.1 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG59950.1 - 1.2 8.8 10.0 2 8.1 10.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RT_RNaseH_2 PF17919.1 GBG59953.1 - 2.4e-31 107.7 0.0 5.9e-16 58.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59953.1 - 4.8e-28 97.5 0.0 9.1e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59953.1 - 8.7e-26 90.8 0.0 1.5e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG59954.1 - 1.1e-31 110.1 0.1 1.8e-31 109.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG59954.1 - 2.8e-13 50.1 0.0 5.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG59954.1 - 2e-12 47.0 0.1 2.6e-11 43.4 0.1 2.7 2 0 0 2 2 2 1 Integrase zinc binding domain eIF-1a PF01176.19 GBG59954.1 - 0.068 13.0 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 ADIP PF11559.8 GBG59955.1 - 0.0038 17.3 10.4 0.0038 17.3 10.4 2.8 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding LMBR1 PF04791.16 GBG59955.1 - 0.36 9.7 6.6 0.56 9.1 6.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Protocadherin PF08374.11 GBG59955.1 - 0.67 9.9 2.7 1.5 8.7 2.7 1.6 1 0 0 1 1 1 0 Protocadherin DUF5069 PF16798.5 GBG59955.1 - 1.5 9.1 8.9 0.15 12.3 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) DUF702 PF05142.12 GBG59955.1 - 4.7 7.7 6.9 0.71 10.4 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) HEAT_2 PF13646.6 GBG59957.1 - 0.024 15.0 0.4 0.75 10.2 0.0 3.3 2 1 0 3 3 3 0 HEAT repeats HEAT_2 PF13646.6 GBG59958.1 - 0.042 14.2 0.2 0.39 11.1 0.0 2.5 1 1 1 2 2 2 0 HEAT repeats Retrotrans_gag PF03732.17 GBG59960.1 - 0.0099 16.1 1.1 1.8 8.9 0.3 2.3 1 1 1 2 2 2 2 Retrotransposon gag protein DUF3437 PF11919.8 GBG59960.1 - 0.027 14.4 0.7 0.1 12.5 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) Glyco_hydro_42C PF08533.10 GBG59960.1 - 0.045 13.5 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain FAT PF02259.23 GBG59961.1 - 6.5e-15 55.2 0.7 6.1e-14 52.0 0.7 2.4 1 1 0 1 1 1 1 FAT domain FAT PF02259.23 GBG59962.1 - 3.9e-15 55.9 1.0 4.4e-14 52.5 1.0 2.4 1 1 0 1 1 1 1 FAT domain DUF659 PF04937.15 GBG59963.1 - 2.9e-33 114.9 0.1 9.2e-33 113.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dapper PF15268.6 GBG59963.1 - 0.48 9.2 42.0 0.75 8.6 42.0 1.2 1 0 0 1 1 1 0 Dapper PA28_beta PF02252.18 GBG59964.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit PI3_PI4_kinase PF00454.27 GBG59967.1 - 2.4e-16 60.3 0.0 2.6e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase THUMP PF02926.17 GBG59969.1 - 1.3e-08 35.1 0.6 5e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 THUMP domain PPP4R2 PF09184.11 GBG59969.1 - 1.1 8.8 13.5 1.8 8.1 13.5 1.4 1 0 0 1 1 1 0 PPP4R2 SspB PF04386.13 GBG59969.1 - 3 7.7 5.5 6 6.7 5.5 1.4 1 0 0 1 1 1 0 Stringent starvation protein B DUF2722 PF10846.8 GBG59969.1 - 4.5 6.1 10.0 6.4 5.6 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIE-A_C PF11521.8 GBG59969.1 - 5.2 7.4 16.0 18 5.7 16.0 1.9 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Nop14 PF04147.12 GBG59972.1 - 0.1 10.8 8.1 0.11 10.6 8.1 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG59972.1 - 0.15 11.4 8.4 0.17 11.2 8.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG59972.1 - 0.16 10.2 6.1 0.19 10.0 6.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Svf1 PF08622.10 GBG59973.1 - 0.022 14.8 0.2 0.039 14.0 0.2 1.3 1 0 0 1 1 1 0 Svf1-like N-terminal lipocalin domain HSP70 PF00012.20 GBG59973.1 - 1.8 6.6 14.1 2.3 6.3 14.1 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4482 PF14818.6 GBG59973.1 - 10 7.0 16.3 0.49 11.3 7.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) GRP PF07172.11 GBG59975.1 - 0.46 11.2 12.3 0.72 10.6 0.0 2.9 2 1 1 3 3 3 0 Glycine rich protein family SUIM_assoc PF16619.5 GBG59977.1 - 6 7.0 8.5 10 6.2 1.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 XRN_M PF17846.1 GBG59980.1 - 1.5e-168 561.4 0.4 4.7e-123 411.4 0.0 2.1 2 0 0 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 GBG59980.1 - 1.2e-47 162.4 0.0 2.1e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 GBG59980.1 - 0.00051 20.0 0.5 0.001 19.1 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle XRN_M PF17846.1 GBG59981.1 - 1.5e-168 561.3 0.4 4.9e-123 411.4 0.0 2.1 2 0 0 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 GBG59981.1 - 1.6e-74 250.4 0.0 5.9e-45 153.6 0.0 2.3 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 GBG59981.1 - 0.00053 19.9 0.5 0.001 19.1 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Peptidase_S64 PF08192.11 GBG59985.1 - 5.4 5.4 8.1 6.4 5.1 8.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Tox-ODYAM1 PF15642.6 GBG59985.1 - 5.9 5.8 9.2 8.8 5.2 9.2 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF1664 PF07889.12 GBG59987.1 - 0.069 13.2 2.5 0.14 12.2 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ADIP PF11559.8 GBG59987.1 - 1.2 9.2 9.1 2.2 8.4 9.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Nsp1_C PF05064.13 GBG59987.1 - 1.2 9.0 5.6 0.41 10.4 1.6 2.3 3 0 0 3 3 3 0 Nsp1-like C-terminal region Macoilin PF09726.9 GBG59990.1 - 0.16 10.5 3.2 0.19 10.3 3.2 1.0 1 0 0 1 1 1 0 Macoilin family COMP PF11598.8 GBG59990.1 - 0.17 12.4 0.9 0.32 11.5 0.9 1.4 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Adaptin_binding PF10199.9 GBG59990.1 - 0.19 12.3 2.9 0.62 10.7 3.1 1.7 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF572 PF04502.13 GBG59990.1 - 0.32 10.6 3.4 0.42 10.2 3.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RPN6_N PF18055.1 GBG59990.1 - 0.42 11.0 4.9 1.2 9.5 4.1 1.9 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain HC2 PF07382.11 GBG59991.1 - 0.2 11.7 6.8 0.3 11.2 6.8 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 TFIIA PF03153.13 GBG59992.1 - 0.028 14.5 8.0 0.031 14.3 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Na_trans_assoc PF06512.13 GBG59992.1 - 0.045 14.0 8.3 0.054 13.8 8.3 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated CPSF100_C PF13299.6 GBG59992.1 - 0.53 10.4 7.2 0.77 9.9 7.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 GBG59992.1 - 2.2 6.4 21.0 2.5 6.2 21.0 1.0 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 GBG59992.1 - 2.5 6.1 5.5 2.9 5.9 5.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_polI_A34 PF08208.11 GBG59992.1 - 3.1 7.8 13.9 4.2 7.4 13.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 GBG59992.1 - 3.7 5.7 16.6 4.3 5.5 16.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG59992.1 - 5 6.9 14.0 6.4 6.5 14.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG59992.1 - 7.6 5.2 6.0 9.1 4.9 6.0 1.1 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG59993.1 - 1.3e-36 124.6 0.0 2.1e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59993.1 - 4.5e-33 113.7 0.0 1.3e-32 112.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59993.1 - 3.7e-07 29.9 0.0 7.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C48 PF02902.19 GBG59994.1 - 1.1e-31 110.3 0.0 2.1e-19 70.2 0.0 2.7 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain RVT_1 PF00078.27 GBG59995.1 - 8.3e-30 104.0 0.1 1.9e-29 102.8 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59995.1 - 4.2e-25 87.7 0.0 1.2e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59995.1 - 1.8e-23 82.8 0.1 5.7e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG59995.1 - 3e-17 62.5 1.5 3.4e-17 62.3 0.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG59995.1 - 9.9e-09 35.7 0.0 4.1e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG59995.1 - 1.1e-07 32.3 0.0 4.4e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG59995.1 - 4.5e-06 26.5 0.0 9.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG59995.1 - 0.00014 22.1 5.5 0.0051 17.1 0.1 4.2 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG59995.1 - 0.00023 21.0 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG59995.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger ABC_membrane_2 PF06472.15 GBG59996.1 - 6.8e-61 206.0 0.2 1e-60 205.5 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GBG59996.1 - 1.2e-21 77.6 0.0 2.7e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GBG59996.1 - 0.0011 19.4 1.3 0.035 14.5 0.2 2.9 3 1 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 GBG59996.1 - 0.0015 18.0 0.0 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GBG59996.1 - 0.0027 17.4 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GBG59996.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GBG59996.1 - 0.019 15.5 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 GBG59996.1 - 0.041 13.5 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GBG59996.1 - 0.045 13.5 0.0 0.27 10.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GBG59996.1 - 0.064 13.2 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 GBG59996.1 - 0.077 13.5 0.0 0.64 10.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain SecY PF00344.20 GBG59996.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 SecY translocase NACHT PF05729.12 GBG59996.1 - 0.15 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain SbmA_BacA PF05992.12 GBG59996.1 - 0.19 11.1 0.6 0.51 9.7 0.3 1.8 2 0 0 2 2 2 0 SbmA/BacA-like family DDE_Tnp_4 PF13359.6 GBG59997.1 - 4.8e-13 49.1 0.8 3.3e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG59997.1 - 1.7e-07 31.1 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein RVT_1 PF00078.27 GBG59998.1 - 9.7e-30 103.7 0.1 1.5e-29 103.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG59999.1 - 1.4e-27 95.7 0.0 2.4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG59999.1 - 2e-25 89.1 0.0 3.8e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG59999.1 - 4.2e-11 42.8 0.1 7.5e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG59999.1 - 0.54 8.4 6.9 0.66 8.1 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG59999.1 - 7.8 4.6 7.5 11 4.2 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DDE_Tnp_4 PF13359.6 GBG60000.1 - 4.3e-06 26.5 0.1 1e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60000.1 - 0.031 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG60001.1 - 1.4e-06 28.6 2.9 1.4e-06 28.6 2.9 2.0 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG60001.1 - 0.00082 19.4 1.3 0.00082 19.4 1.3 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG60001.1 - 0.00084 19.5 0.4 0.0017 18.6 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG60001.1 - 0.0033 17.6 0.1 0.0075 16.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG60001.1 - 0.01 16.1 0.4 0.027 14.8 0.4 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3472 PF11958.8 GBG60001.1 - 0.049 14.1 1.0 0.08 13.4 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) GRP PF07172.11 GBG60001.1 - 0.28 11.9 12.8 1.7 9.4 5.5 2.4 2 0 0 2 2 2 0 Glycine rich protein family DUF5427 PF10310.9 GBG60002.1 - 0.72 8.7 21.7 0.84 8.5 21.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SpoIIP PF07454.11 GBG60002.1 - 7.6 5.9 24.4 8.7 5.7 24.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Neur_chan_memb PF02932.16 GBG60002.1 - 7.6 6.5 8.3 7.8 6.5 8.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_Rpc4 PF05132.14 GBG60002.1 - 8.6 6.8 21.7 12 6.3 21.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC27 PF09507.10 GBG60006.1 - 0.0045 16.4 0.9 0.0045 16.4 0.9 2.3 3 0 0 3 3 3 1 DNA polymerase subunit Cdc27 RuvA_C PF07499.13 GBG60006.1 - 0.031 14.7 0.2 0.083 13.4 0.2 1.8 1 0 0 1 1 1 0 RuvA, C-terminal domain DUF4820 PF16091.5 GBG60006.1 - 0.069 12.5 0.4 0.15 11.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Gluconate_2-dh3 PF13618.6 GBG60006.1 - 0.13 12.5 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 CDC45 PF02724.14 GBG60006.1 - 0.31 9.3 8.2 0.55 8.4 8.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG60008.1 - 1.3e-15 57.6 0.0 1.9e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) WVELL PF14043.6 GBG60008.1 - 0.062 13.1 0.0 0.24 11.2 0.0 2.0 2 1 0 2 2 2 0 WVELL protein IFT57 PF10498.9 GBG60009.1 - 1.7 7.6 2.9 3.6 6.4 2.9 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DnaJ PF00226.31 GBG60010.1 - 3.2e-17 62.4 0.0 6.4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain RhlB PF12300.8 GBG60010.1 - 0.0069 16.5 4.2 0.011 15.8 4.2 1.3 1 0 0 1 1 1 1 ATP-dependent RNA helicase RhlB Cys_rich_KTR PF14205.6 GBG60010.1 - 0.008 16.0 1.9 0.017 14.9 1.9 1.4 1 0 0 1 1 1 1 Cysteine-rich KTR TrmO_C PF18389.1 GBG60010.1 - 0.094 12.8 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 TrmO C-terminal domain SRP-alpha_N PF04086.13 GBG60015.1 - 0.92 9.4 15.3 0.071 13.0 8.3 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Myb_DNA-bind_4 PF13837.6 GBG60016.1 - 0.2 12.1 1.0 0.32 11.4 1.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MAP17 PF15807.5 GBG60016.1 - 0.21 11.8 0.2 0.41 10.9 0.2 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LapA_dom PF06305.11 GBG60016.1 - 0.27 11.1 0.5 0.47 10.3 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DDE_Tnp_4 PF13359.6 GBG60018.1 - 7.7e-28 97.2 0.2 2.8e-27 95.3 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60018.1 - 9.1e-15 54.8 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG60018.1 - 0.00027 20.6 0.5 0.0014 18.3 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG60018.1 - 0.073 13.4 0.0 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain RVT_1 PF00078.27 GBG60019.1 - 9.6e-28 97.2 0.1 1.4e-27 96.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60019.1 - 2.3e-18 66.0 0.0 2.6e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG60019.1 - 1.4e-12 47.3 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG60019.1 - 1.9e-07 31.3 0.0 4.7e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60020.1 - 3.7e-29 100.7 0.0 2e-15 56.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60020.1 - 3.7e-28 97.9 0.0 8.4e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60020.1 - 2e-26 92.9 0.1 3.4e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60020.1 - 9.9e-13 48.0 0.1 9.9e-13 48.0 0.1 2.6 4 0 0 4 4 4 1 Integrase zinc binding domain Chromo PF00385.24 GBG60020.1 - 6.2e-10 38.8 0.0 1.5e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG60020.1 - 0.00025 21.2 0.0 0.0006 20.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG60020.1 - 0.035 14.7 0.0 0.089 13.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG60021.1 - 0.00074 19.3 3.4 0.0013 18.5 3.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG60021.1 - 0.013 15.6 1.1 0.013 15.6 1.1 1.7 2 0 0 2 2 2 0 Zinc knuckle FlaC_arch PF05377.11 GBG60021.1 - 1.2 9.6 5.9 1.8 9.0 0.6 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 GBG60021.1 - 2.2 9.0 25.4 0.36 11.5 0.6 3.9 2 1 2 4 4 4 0 Initiation control protein YabA DAGAT PF03982.13 GBG60023.1 - 5.6e-18 64.9 0.2 2.5e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Diacylglycerol acyltransferase DUF4187 PF13821.6 GBG60023.1 - 0.0038 17.0 0.8 0.012 15.4 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG60023.1 - 0.0077 16.5 0.6 0.0077 16.5 0.6 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DAGAT PF03982.13 GBG60024.1 - 5.9e-18 64.8 0.2 2.5e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Merozoite_SPAM PF07133.11 GBG60024.1 - 0.00014 22.0 27.3 0.00014 22.0 27.3 1.7 2 0 0 2 2 1 1 Merozoite surface protein (SPAM) SDA1 PF05285.12 GBG60024.1 - 0.00036 20.1 14.3 0.0008 18.9 14.3 1.5 1 0 0 1 1 1 1 SDA1 TFIIF_alpha PF05793.12 GBG60024.1 - 0.00046 18.9 10.9 0.00081 18.1 10.9 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BSP_II PF05432.11 GBG60024.1 - 0.0016 18.2 22.1 0.0037 17.0 22.1 1.5 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Retrotrans_gag PF03732.17 GBG60024.1 - 0.0077 16.5 0.6 0.0077 16.5 0.6 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG60024.1 - 0.012 15.4 0.8 0.012 15.4 0.8 2.8 2 1 0 2 2 1 0 Domain of unknown function (DUF4187) DNA_pol_phi PF04931.13 GBG60024.1 - 0.03 12.4 22.1 0.048 11.8 22.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 GBG60024.1 - 0.063 13.2 15.0 0.18 11.7 15.0 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region CSG2 PF16965.5 GBG60024.1 - 0.067 12.1 0.9 0.12 11.2 0.9 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Nop14 PF04147.12 GBG60024.1 - 0.083 11.1 21.7 0.13 10.5 21.7 1.2 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 GBG60024.1 - 0.12 11.6 11.1 0.23 10.6 11.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FHIPEP PF00771.20 GBG60024.1 - 0.13 10.7 0.3 0.25 9.8 0.3 1.4 1 0 0 1 1 1 0 FHIPEP family BUD22 PF09073.10 GBG60024.1 - 0.13 11.5 12.8 0.35 10.1 12.8 1.7 1 0 0 1 1 1 0 BUD22 Connexin PF00029.19 GBG60024.1 - 0.18 11.5 4.5 0.47 10.2 4.5 1.6 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 GBG60024.1 - 0.22 9.8 18.0 0.43 8.8 18.0 1.4 1 0 0 1 1 1 0 CDC45-like protein CLN3 PF02487.17 GBG60024.1 - 0.48 9.4 3.4 1.1 8.3 3.4 1.5 1 0 0 1 1 1 0 CLN3 protein DUF966 PF06136.13 GBG60024.1 - 0.55 9.9 16.8 0.15 11.7 13.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF966) DUF2052 PF09747.9 GBG60024.1 - 0.65 10.1 24.8 0.044 13.9 17.5 2.5 3 0 0 3 3 2 0 Coiled-coil domain containing protein (DUF2052) Mpp10 PF04006.12 GBG60024.1 - 0.82 8.0 24.7 1.5 7.1 24.7 1.3 1 0 0 1 1 1 0 Mpp10 protein RNA_pol_Rpc4 PF05132.14 GBG60024.1 - 0.91 9.9 6.5 3.7 8.0 6.5 2.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 FSIP1 PF15554.6 GBG60024.1 - 0.97 8.5 19.6 1.8 7.5 19.6 1.3 1 0 0 1 1 1 0 FSIP1 family Lipin_mid PF16876.5 GBG60024.1 - 0.99 9.6 0.0 0.99 9.6 0.0 2.8 3 0 0 3 3 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain PPP4R2 PF09184.11 GBG60024.1 - 1.2 8.7 20.5 0.1 12.2 15.3 1.9 2 0 0 2 2 2 0 PPP4R2 Tim54 PF11711.8 GBG60024.1 - 3.1 6.5 12.6 6.5 5.4 12.6 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ATHILA PF03078.15 GBG60024.1 - 3.1 6.5 12.7 6.1 5.5 12.7 1.4 1 0 0 1 1 1 0 ATHILA ORF-1 family DUF4820 PF16091.5 GBG60024.1 - 3.9 6.8 11.3 12 5.1 11.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 GBG60024.1 - 4 7.1 15.6 16 5.1 15.6 2.1 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.12 GBG60024.1 - 4 7.2 18.4 1.8 8.3 15.6 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3391 PF11871.8 GBG60024.1 - 5.1 7.6 10.2 18 5.8 10.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) CCSAP PF15748.5 GBG60024.1 - 5.4 7.1 24.0 0.75 9.9 17.2 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SOBP PF15279.6 GBG60024.1 - 5.6 7.5 11.3 17 5.9 11.3 1.7 1 0 0 1 1 1 0 Sine oculis-binding protein Nop53 PF07767.11 GBG60024.1 - 5.8 6.2 23.0 12 5.2 23.0 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DDHD PF02862.17 GBG60024.1 - 7.7 6.6 7.7 1.7 8.7 3.7 2.0 2 0 0 2 2 1 0 DDHD domain RPA43_OB PF17875.1 GBG60024.1 - 10 6.8 8.7 36 5.0 8.7 1.9 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Plavaka PF18759.1 GBG60025.1 - 6.1e-21 75.0 0.7 1.2e-20 74.0 0.7 1.4 1 0 0 1 1 1 1 Plavaka transposase bMG10 PF17973.1 GBG60027.1 - 0.044 14.0 0.2 17 5.6 0.0 3.7 2 1 1 3 3 3 0 Bacterial Alpha-2-macroglobulin MG10 domain Sua5_yciO_yrdC PF01300.18 GBG60028.1 - 1.6e-40 138.5 0.0 2.4e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination Sod_Fe_C PF02777.18 GBG60029.1 - 2.7e-36 123.8 0.4 5.8e-36 122.8 0.4 1.6 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GBG60029.1 - 4.8e-26 91.0 0.5 2e-25 89.1 0.1 2.1 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Histone PF00125.24 GBG60030.1 - 1.2e-22 80.6 0.1 1.2e-22 80.6 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 GP24_25 PF17388.2 GBG60030.1 - 0.032 14.2 0.0 5 7.1 0.1 2.8 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 Ribosomal_L3 PF00297.22 GBG60031.1 - 8.5e-46 156.6 0.5 9.3e-46 156.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF19 PF01579.18 GBG60032.1 - 0.04 13.7 2.4 0.095 12.5 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF19) SprT-like PF10263.9 GBG60033.1 - 1e-25 89.8 0.0 2.1e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 SprT-like family zf-WRNIP1_ubi PF18279.1 GBG60033.1 - 0.02 15.5 2.5 0.024 15.3 0.4 2.3 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain UBZ_FAAP20 PF15750.5 GBG60033.1 - 0.028 14.4 0.4 0.079 12.9 0.4 1.8 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger Efg1 PF10153.9 GBG60033.1 - 0.22 11.9 3.7 0.68 10.3 3.7 1.8 1 0 0 1 1 1 0 rRNA-processing protein Efg1 Tox-MPTase5 PF15641.6 GBG60034.1 - 0.0041 17.1 0.1 0.0052 16.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase toxin 5 Rad54_N PF08658.10 GBG60035.1 - 0.063 13.4 6.3 0.098 12.8 6.3 1.2 1 0 0 1 1 1 0 Rad54 N terminal Hid1 PF12722.7 GBG60035.1 - 0.31 9.1 5.0 0.34 9.0 5.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM176 PF14851.6 GBG60035.1 - 0.76 9.4 10.0 1.8 8.2 10.0 1.7 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 GBG60035.1 - 1.5 8.5 12.8 2.5 7.9 12.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Rubis-subs-bind PF09273.11 GBG60037.1 - 3.1e-15 57.0 0.7 6.4e-15 56.0 0.7 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Hexapep PF00132.24 GBG60039.1 - 5.4e-17 60.8 4.9 3.2e-05 23.5 0.4 3.7 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GBG60039.1 - 2.8e-06 27.0 6.3 0.00027 20.6 0.4 3.4 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 GBG60039.1 - 0.0018 17.3 0.9 0.0032 16.5 0.9 1.3 1 1 0 1 1 1 1 L-fucokinase MMR_HSR1 PF01926.23 GBG60040.1 - 4.5e-23 81.5 0.0 9.7e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG60040.1 - 2.2e-07 30.9 0.0 0.00012 22.0 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GBG60040.1 - 6.3e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GBG60040.1 - 1.2e-05 24.9 0.0 0.0017 17.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GBG60040.1 - 0.0025 17.3 0.0 0.0053 16.2 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 GBG60040.1 - 0.0056 16.7 0.1 0.15 12.1 0.1 2.3 1 1 1 2 2 2 1 Dynamin family TniB PF05621.11 GBG60040.1 - 0.033 13.6 0.0 0.077 12.4 0.0 1.6 1 1 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 GBG60040.1 - 0.039 13.7 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 GBG60040.1 - 0.055 13.7 0.1 0.94 9.7 0.0 2.6 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GBG60040.1 - 0.12 12.0 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Ras family Ribosomal_60s PF00428.19 GBG60040.1 - 3.4 8.3 10.8 28 5.4 0.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein RINGv PF12906.7 GBG60042.1 - 4.7e-09 36.2 7.4 1.5e-08 34.6 7.4 2.0 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 GBG60042.1 - 0.071 13.5 7.5 0.1 13.0 4.8 2.8 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.8 GBG60042.1 - 0.37 11.0 2.5 0.97 9.7 2.5 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 GBG60042.1 - 0.77 10.1 5.5 3.3 8.1 5.5 2.2 1 0 0 1 1 1 0 RING-like domain DUF659 PF04937.15 GBG60043.1 - 2.1e-26 92.6 0.0 4.1e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60043.1 - 2.5e-07 30.4 0.2 5.8e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2207 PF09972.9 GBG60044.1 - 0.00082 18.3 2.8 0.0012 17.8 2.8 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) MDM10 PF12519.8 GBG60044.1 - 0.11 11.4 3.5 0.15 10.9 3.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3807 PF12720.7 GBG60044.1 - 0.19 12.0 9.2 0.29 11.4 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Connexin PF00029.19 GBG60044.1 - 0.49 10.1 5.9 0.93 9.2 5.9 1.5 1 0 0 1 1 1 0 Connexin Eapp_C PF10238.9 GBG60044.1 - 0.58 10.2 8.8 34 4.5 10.0 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4770 PF15994.5 GBG60044.1 - 1.8 8.8 9.6 2.9 8.1 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Vfa1 PF08432.10 GBG60044.1 - 2.4 8.5 20.5 0.68 10.2 16.8 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PPL5 PF18168.1 GBG60044.1 - 3.7 6.8 5.9 6 6.1 5.9 1.3 1 0 0 1 1 1 0 Prim-pol family 5 YL1 PF05764.13 GBG60044.1 - 7.6 6.6 22.1 11 6.1 22.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Rtf2 PF04641.12 GBG60044.1 - 7.6 5.8 18.8 12 5.1 18.8 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger TAF4 PF05236.14 GBG60044.1 - 8.1 6.1 16.1 53 3.4 17.6 1.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family FUN14 PF04930.15 GBG60044.1 - 8.7 6.8 8.2 11 6.5 0.1 2.8 2 1 0 2 2 2 0 FUN14 family zf-CCHC PF00098.23 GBG60047.1 - 1e-06 28.5 3.7 3.1e-06 27.0 3.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG60047.1 - 0.052 13.3 3.7 0.12 12.1 3.7 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Dimer_Tnp_hAT PF05699.14 GBG60048.1 - 0.00019 21.1 0.1 0.00037 20.2 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG60049.1 - 1.7e-19 70.2 0.0 3.2e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60049.1 - 2.8e-10 40.1 0.0 8.2e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60049.1 - 3.5e-08 33.7 0.2 1.2e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DNA_pol_phi PF04931.13 GBG60050.1 - 0.38 8.8 20.9 0.45 8.6 20.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG60050.1 - 0.84 7.8 13.6 1.2 7.3 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG60050.1 - 0.88 7.7 23.9 1.1 7.4 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 GBG60050.1 - 0.92 9.3 10.3 1.5 8.6 10.3 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.12 GBG60050.1 - 3.3 7.1 20.8 4.1 6.7 20.8 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG60050.1 - 3.5 7.3 20.8 5.9 6.5 20.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NPR3 PF03666.13 GBG60050.1 - 5.3 5.7 5.3 6 5.5 5.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RVT_1 PF00078.27 GBG60051.1 - 3.1e-13 49.8 0.1 4.8e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60051.1 - 4.6e-12 45.9 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60051.1 - 0.027 14.7 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase eIF3_N PF09440.10 GBG60052.1 - 0.24 11.8 0.2 0.43 11.0 0.2 1.3 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain SDA1 PF05285.12 GBG60058.1 - 0.34 10.3 37.8 0.44 9.9 37.8 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG60058.1 - 0.44 9.8 33.3 0.55 9.5 33.3 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG60058.1 - 0.49 8.5 34.8 0.64 8.2 34.8 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG60058.1 - 0.63 8.6 30.5 0.79 8.2 30.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 GBG60058.1 - 2.4 7.8 27.5 3.4 7.3 27.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SID-1_RNA_chan PF13965.6 GBG60058.1 - 2.7 6.3 3.4 3.2 6.1 3.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LAP1C PF05609.12 GBG60058.1 - 6.5 5.7 18.9 8 5.4 18.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DASH_Dad4 PF08650.10 GBG60061.1 - 0.038 14.0 0.3 0.13 12.2 0.2 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad4 Prominin PF05478.11 GBG60061.1 - 0.044 11.7 0.4 0.061 11.3 0.4 1.2 1 0 0 1 1 1 0 Prominin Spore_III_AB PF09548.10 GBG60061.1 - 0.23 11.6 6.8 2.3 8.3 0.5 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) 40S_SA_C PF16122.5 GBG60061.1 - 0.24 12.8 3.6 8 7.9 0.1 2.7 2 0 0 2 2 2 0 40S ribosomal protein SA C-terminus MCU PF04678.13 GBG60061.1 - 0.25 11.4 6.5 5 7.2 0.6 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Phlebovirus_NSM PF07246.11 GBG60061.1 - 0.99 8.7 13.7 0.098 12.0 4.1 2.1 1 1 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DDE_Tnp_4 PF13359.6 GBG60062.1 - 4.4e-31 107.7 0.0 6.4e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60062.1 - 1.2e-12 47.9 0.0 1.9e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG60062.1 - 0.003 17.2 0.3 1.7 8.2 0.2 2.4 1 1 1 2 2 2 2 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG60063.1 - 4.4e-25 87.6 0.0 8.8e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60063.1 - 1.8e-24 86.0 0.0 3.7e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60063.1 - 6.9e-19 67.7 0.2 1.5e-18 66.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60063.1 - 9.4e-08 32.3 0.1 3.5e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG60063.1 - 0.081 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger UCH PF00443.29 GBG60064.1 - 1e-14 54.7 0.1 1.5e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG60064.1 - 0.00063 19.4 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RVT_1 PF00078.27 GBG60065.1 - 2.8e-29 102.2 0.1 3.7e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60065.1 - 0.00014 21.9 0.0 0.0004 20.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase UCH PF00443.29 GBG60066.1 - 9.3e-14 51.5 0.5 1.4e-13 51.0 0.5 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG60066.1 - 2.8e-08 33.7 0.3 3.8e-08 33.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Phasin PF05597.11 GBG60066.1 - 0.0045 17.0 6.3 0.22 11.5 1.0 2.7 3 0 0 3 3 3 2 Poly(hydroxyalcanoate) granule associated protein (phasin) PMC2NT PF08066.12 GBG60066.1 - 0.02 15.6 0.1 0.069 13.8 0.1 1.9 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Baculo_F PF12259.8 GBG60066.1 - 0.15 10.6 0.6 0.24 9.9 0.3 1.2 1 1 0 1 1 1 0 Baculovirus F protein DivIVA PF05103.13 GBG60066.1 - 4 7.5 12.5 0.061 13.4 2.4 2.2 1 1 0 2 2 2 0 DivIVA protein RVT_1 PF00078.27 GBG60067.1 - 2.4e-26 92.7 0.0 4.1e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60067.1 - 6.6e-11 42.1 0.0 1.5e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60068.1 - 7.9e-07 29.6 0.2 2.4e-06 28.0 0.2 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60068.1 - 3.2e-06 27.7 0.2 1.2e-05 25.8 0.2 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60068.1 - 0.026 14.3 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG60068.1 - 0.071 12.8 0.3 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG60068.1 - 0.16 12.1 2.2 0.29 11.3 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle LRR_4 PF12799.7 GBG60069.1 - 1.6e-05 25.2 2.9 4.2 7.9 0.1 6.8 6 2 2 8 8 8 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG60069.1 - 0.07 13.2 1.6 1e+02 3.4 0.0 5.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_2 PF07723.13 GBG60069.1 - 0.68 10.7 0.1 0.68 10.7 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat RVT_1 PF00078.27 GBG60070.1 - 0.003 17.1 0.1 0.0053 16.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG60070.1 - 0.027 14.0 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family baeRF_family10 PF18854.1 GBG60070.1 - 0.044 14.0 0.6 0.11 12.8 0.6 1.7 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 CCDC-167 PF15188.6 GBG60070.1 - 0.062 13.6 3.2 0.12 12.7 3.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 LRR_4 PF12799.7 GBG60071.1 - 1.5e-06 28.4 3.1 0.59 10.6 0.7 5.4 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) Myc_N PF01056.18 GBG60071.1 - 0.019 14.9 2.9 0.031 14.2 2.9 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Transp_inhibit PF18791.1 GBG60071.1 - 0.08 12.5 0.0 16 5.1 0.0 2.9 3 0 0 3 3 3 0 Transport inhibitor response 1 protein domain Pox_Ag35 PF03286.14 GBG60071.1 - 4.6 7.0 12.8 9.8 5.9 12.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein LRR_8 PF13855.6 GBG60071.1 - 6.6 6.6 6.2 2.8 7.8 0.4 3.2 4 0 0 4 4 4 0 Leucine rich repeat RVT_1 PF00078.27 GBG60072.1 - 2.3e-31 109.0 0.0 4.4e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60072.1 - 6.9e-17 61.3 0.1 2.6e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60072.1 - 2.9e-05 24.3 0.2 7.4e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Swi6_N PF18530.1 GBG60073.1 - 0.035 14.2 0.1 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Swi6 N-terminal domain Vif PF00559.17 GBG60073.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral Vif (Viral infectivity) protein CENP-Q PF13094.6 GBG60074.1 - 0.005 17.1 4.1 0.01 16.0 4.1 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit RVP_2 PF08284.11 GBG60076.1 - 1.3e-06 28.2 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60076.1 - 0.00013 21.7 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG60076.1 - 0.00033 21.2 0.0 0.00057 20.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60076.1 - 0.00056 20.4 0.0 0.00092 19.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG60076.1 - 0.094 12.2 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_tran_CTD PF16326.5 GBG60077.1 - 0.0097 16.1 0.8 0.13 12.5 0.3 2.5 1 1 0 2 2 2 1 ABC transporter C-terminal domain LegC3_N PF18654.1 GBG60077.1 - 0.016 14.4 1.2 0.021 14.1 1.2 1.3 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain ATF7IP_BD PF16788.5 GBG60077.1 - 0.028 14.5 0.4 0.046 13.8 0.4 1.5 1 1 0 1 1 1 0 ATF-interacting protein binding domain BRE1 PF08647.11 GBG60077.1 - 0.029 14.4 0.8 0.089 12.9 0.6 2.0 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 GBG60077.1 - 0.05 13.6 2.5 1.2 9.1 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 GBG60077.1 - 0.098 13.1 0.3 14 6.2 0.0 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 GBG60077.1 - 0.11 12.9 0.2 0.11 12.9 0.2 3.1 3 1 0 3 3 3 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 GBG60077.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 GBG60077.1 - 0.28 11.7 3.1 8 7.0 3.0 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 GBG60077.1 - 0.83 9.5 4.2 1.3 8.9 1.4 2.6 2 1 0 2 2 2 0 Septum formation initiator FlxA PF14282.6 GBG60077.1 - 1.3 9.0 11.0 4.4 7.3 0.1 2.7 2 1 1 3 3 3 0 FlxA-like protein SlyX PF04102.12 GBG60077.1 - 2.8 8.6 6.9 3.2 8.4 0.9 3.2 1 1 0 2 2 2 0 SlyX CLIP1_ZNF PF16641.5 GBG60078.1 - 0.018 14.9 0.6 0.034 14.0 0.6 1.5 1 0 0 1 1 1 0 CLIP1 zinc knuckle CDC45 PF02724.14 GBG60078.1 - 1.5 7.1 33.4 0.077 11.3 21.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Aldo_ket_red PF00248.21 GBG60079.1 - 1.7e-63 214.6 0.0 1.7e-41 142.4 0.0 2.3 2 1 0 2 2 2 2 Aldo/keto reductase family DUF3246 PF11596.8 GBG60079.1 - 0.0044 16.5 6.5 0.0044 16.5 6.5 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3246) GHMP_kinases_N PF00288.26 GBG60079.1 - 0.56 10.5 19.3 0.33 11.2 5.5 3.3 3 0 0 3 3 3 0 GHMP kinases N terminal domain NOA36 PF06524.12 GBG60079.1 - 0.57 9.5 8.7 1.1 8.6 8.7 1.3 1 0 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.10 GBG60079.1 - 8.9 7.1 14.8 0.48 11.1 7.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Cwf_Cwc_15 PF04889.12 GBG60079.1 - 9.9 5.8 15.0 20 4.8 15.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein REV PF00424.18 GBG60080.1 - 0.02 14.9 0.5 0.037 14.1 0.3 1.6 1 1 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Hairpins PF04877.12 GBG60080.1 - 0.086 12.5 0.2 0.13 11.9 0.2 1.4 1 1 0 1 1 1 0 HrpZ WDCP PF15390.6 GBG60080.1 - 4.8 5.5 10.1 5 5.4 10.1 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family ANXA2R PF15721.5 GBG60080.1 - 5.3 7.5 10.2 4.9 7.6 4.9 2.0 1 1 1 2 2 2 0 Annexin-2 receptor RE_AlwI PF09491.10 GBG60080.1 - 6.2 5.5 14.8 1.5 7.6 11.4 1.6 1 1 1 2 2 2 0 AlwI restriction endonuclease FAM60A PF15396.6 GBG60080.1 - 8.4 6.3 11.3 9.9 6.1 11.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PA26 PF04636.13 GBG60080.1 - 9.6 5.0 13.7 11 4.8 13.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RT_RNaseH_2 PF17919.1 GBG60081.1 - 1.5e-34 118.0 0.0 6.6e-34 115.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60081.1 - 2.6e-32 112.1 0.1 4.7e-32 111.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60081.1 - 7.9e-31 106.5 0.1 1.9e-30 105.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG60081.1 - 5.9e-07 30.1 1.1 1.8e-06 28.5 0.2 2.3 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-CCHC_3 PF13917.6 GBG60081.1 - 0.00096 19.1 1.5 0.0024 17.8 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG60081.1 - 0.003 17.8 0.2 0.027 14.8 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein ANAPC4_WD40 PF12894.7 GBG60081.1 - 0.026 14.8 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3863 PF12979.7 GBG60081.1 - 0.079 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) RVT_1 PF00078.27 GBG60082.1 - 5.4e-28 98.0 0.1 1.4e-27 96.7 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60082.1 - 2.2e-21 76.1 0.0 5e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60082.1 - 3.2e-20 72.0 0.0 9.2e-20 70.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG60082.1 - 5.1e-09 36.6 0.1 2.3e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG60082.1 - 1.3e-08 34.7 0.0 3.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60082.1 - 1.6e-06 28.6 0.0 4.9e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60082.1 - 0.00061 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG60082.1 - 0.0039 17.4 0.2 0.044 14.1 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG60083.1 - 2.3e-30 105.8 0.9 1.3e-29 103.3 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60083.1 - 1.9e-22 79.5 0.0 6.1e-22 77.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60083.1 - 3.8e-22 78.2 0.0 1.1e-21 76.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60083.1 - 8.3e-12 45.0 1.0 1.4e-11 44.4 0.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG60083.1 - 0.00084 19.6 2.2 0.0079 16.4 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein CAMP_factor PF07373.11 GBG60083.1 - 0.016 14.8 1.3 0.046 13.3 1.2 1.7 1 1 0 1 1 1 0 CAMP factor (Cfa) DUF16 PF01519.16 GBG60083.1 - 0.15 12.6 0.9 0.51 10.9 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 GBG60083.1 - 0.24 11.6 2.8 0.57 10.4 1.6 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 GBG60083.1 - 2.7 8.3 9.1 0.22 11.8 0.4 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Csm1_N PF18504.1 GBG60083.1 - 9.7 6.6 10.9 0.13 12.6 1.5 2.8 2 1 1 3 3 3 0 Csm1 N-terminal domain Rap1-DNA-bind PF09197.10 GBG60084.1 - 0.016 15.8 0.4 0.027 15.1 0.4 1.3 1 0 0 1 1 1 0 Rap1, DNA-binding DUF3464 PF11947.8 GBG60084.1 - 0.068 12.9 0.7 0.12 12.1 0.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3738 PF12543.8 GBG60084.1 - 0.11 12.7 0.2 0.16 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) rve PF00665.26 GBG60085.1 - 1.2e-07 31.9 0.0 2.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG60085.1 - 0.04 13.7 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain 5-FTHF_cyc-lig PF01812.20 GBG60086.1 - 0.015 15.2 0.7 0.081 12.8 0.0 2.0 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family GvpG PF05120.12 GBG60086.1 - 0.02 14.9 5.6 0.046 13.7 5.6 1.7 1 0 0 1 1 1 0 Gas vesicle protein G PI3_PI4_kinase PF00454.27 GBG60086.1 - 0.044 13.6 0.6 0.044 13.6 0.6 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase HAUS6_N PF14661.6 GBG60086.1 - 0.39 10.3 9.5 0.61 9.6 9.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PA26 PF04636.13 GBG60086.1 - 0.61 8.9 6.7 0.66 8.8 6.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC27 PF09507.10 GBG60086.1 - 0.66 9.3 20.2 0.81 9.0 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 4HB_MCP_1 PF12729.7 GBG60086.1 - 2.7 7.5 12.9 0.28 10.7 7.9 1.7 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction CAF1 PF04857.20 GBG60086.1 - 2.9 7.0 5.7 3 6.9 5.7 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease FmdE PF02663.14 GBG60086.1 - 7.9 6.5 8.7 4.4 7.3 5.5 1.9 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Glyco_tranf_2_3 PF13641.6 GBG60089.1 - 1.2e-28 100.6 0.0 1.6e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG60089.1 - 2.8e-23 82.9 1.4 2.8e-23 82.9 1.4 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG60089.1 - 1.1e-21 77.4 0.0 1.7e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 GBG60089.1 - 5.1e-21 74.9 1.0 4.9e-10 38.6 0.5 2.9 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 GBG60089.1 - 7.4e-12 45.1 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF2569 PF10754.9 GBG60089.1 - 1 9.8 8.0 0.17 12.3 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) gag-asp_proteas PF13975.6 GBG60090.1 - 2.3e-06 28.1 0.4 1.3e-05 25.7 0.0 2.3 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60090.1 - 0.00013 22.5 0.1 0.00059 20.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG60090.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Ribosomal_S24e PF01282.19 GBG60091.1 - 1e-36 124.7 0.0 2.2e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e Integrase_H2C2 PF17921.1 GBG60093.1 - 2.6e-09 37.0 0.1 2.6e-09 37.0 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG60093.1 - 1.4e-07 31.3 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG60093.1 - 1.7e-07 31.3 0.0 5.4e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG60093.1 - 0.0003 20.9 0.0 0.0011 19.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG60093.1 - 0.00083 19.4 0.1 0.0021 18.0 0.1 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_Zn PF02022.19 GBG60093.1 - 0.24 11.4 1.5 1 9.4 0.4 2.4 2 0 0 2 2 2 0 Integrase Zinc binding domain DDE_Tnp_4 PF13359.6 GBG60094.1 - 1.2e-11 44.5 0.0 5e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60094.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG60095.1 - 0.0049 17.2 0.4 0.17 12.3 0.0 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Inositol_P PF00459.25 GBG60096.1 - 2.2e-50 171.7 0.9 1.4e-49 169.0 0.9 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family DUF4269 PF14091.6 GBG60097.1 - 0.059 13.6 0.0 0.071 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) DUF1564 PF07600.11 GBG60098.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RT_RNaseH PF17917.1 GBG60099.1 - 4.6e-18 65.4 1.0 1.1e-17 64.2 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60099.1 - 7.8e-09 35.5 0.0 2.8e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FWWh PF14922.6 GBG60099.1 - 0.027 14.4 0.1 0.068 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function Phage_GPO PF05929.11 GBG60099.1 - 0.22 11.1 0.0 0.22 11.1 0.0 3.2 2 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase CutA1 PF03091.15 GBG60099.1 - 0.24 11.3 0.1 0.24 11.3 0.1 2.5 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein CDC27 PF09507.10 GBG60099.1 - 0.96 8.8 26.2 1.5 8.1 26.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4407 PF14362.6 GBG60101.1 - 0.001 18.5 13.8 0.013 14.8 6.9 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 GBG60101.1 - 0.0013 19.3 2.1 0.0013 19.3 2.1 3.3 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 GBG60101.1 - 0.025 15.0 0.8 0.49 10.9 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SPARC_Ca_bdg PF10591.9 GBG60101.1 - 0.17 12.2 2.1 0.48 10.8 2.1 1.9 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Retrotrans_gag PF03732.17 GBG60102.1 - 8.2e-06 26.0 0.4 0.0002 21.6 0.3 3.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG60102.1 - 0.055 13.3 0.2 0.2 11.5 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG60102.1 - 0.066 12.6 5.9 0.17 11.2 5.9 1.6 1 0 0 1 1 1 0 FAM76 protein DHR10 PF18595.1 GBG60103.1 - 0.06 13.4 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain SlyX PF04102.12 GBG60103.1 - 0.12 13.0 0.1 0.29 11.8 0.1 1.7 1 0 0 1 1 1 0 SlyX RT_RNaseH_2 PF17919.1 GBG60105.1 - 1.3e-85 281.9 3.9 1.6e-32 111.5 0.0 3.5 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60105.1 - 1.1e-68 228.1 1.7 2.3e-27 95.3 0.5 3.6 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60105.1 - 1.6e-27 96.4 0.1 3.9e-27 95.2 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60105.1 - 6.5e-19 67.8 0.2 1.3e-18 66.9 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60105.1 - 2.3e-10 40.7 0.2 4.7e-07 30.0 0.1 2.9 2 0 0 2 2 2 2 Integrase core domain Chromo PF00385.24 GBG60105.1 - 0.02 14.8 0.3 0.29 11.1 0.0 2.5 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1344 PF07076.11 GBG60105.1 - 0.029 14.3 0.2 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) zf-H2C2 PF09337.10 GBG60105.1 - 0.073 13.3 0.0 0.26 11.6 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger IceA2 PF05862.11 GBG60105.1 - 0.11 12.4 8.1 3.8 7.5 0.3 3.5 3 0 0 3 3 3 0 Helicobacter pylori IceA2 protein Syntaxin-18_N PF10496.9 GBG60105.1 - 0.13 12.6 0.1 11 6.4 0.0 3.3 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus RT_RNaseH_2 PF17919.1 GBG60106.1 - 7.4e-34 115.8 0.0 1.3e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60106.1 - 8.2e-31 107.2 0.1 1.3e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60106.1 - 1.6e-29 102.2 0.1 2.9e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60106.1 - 3.5e-19 68.7 0.1 7.4e-19 67.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG60106.1 - 0.094 13.0 0.0 0.094 13.0 0.0 2.3 3 0 0 3 3 3 0 H2C2 zinc finger REV PF00424.18 GBG60107.1 - 0.076 13.0 0.0 0.076 13.0 0.0 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) RVP_2 PF08284.11 GBG60108.1 - 8.1e-08 32.1 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60108.1 - 9.8e-07 29.3 0.1 2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60108.1 - 0.00021 21.8 0.1 0.00066 20.2 0.1 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG60108.1 - 0.00067 19.6 0.0 0.003 17.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG60108.1 - 0.004 17.0 0.0 0.034 13.9 0.1 2.3 2 1 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG60108.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG60108.1 - 0.022 14.3 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG60109.1 - 9.9e-30 103.7 0.2 2.8e-29 102.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60109.1 - 9.5e-26 89.8 0.0 2e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60109.1 - 2.9e-25 88.6 0.0 5e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG60109.1 - 0.044 12.9 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Integrin_b_cyt PF08725.11 GBG60109.1 - 0.045 13.4 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain zf-CCHC PF00098.23 GBG60111.1 - 0.0001 22.2 1.8 0.00016 21.6 1.8 1.3 1 0 0 1 1 1 1 Zinc knuckle PNISR PF15996.5 GBG60111.1 - 1.7 8.9 29.3 4 7.7 29.3 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Apc13p PF05839.11 GBG60111.1 - 3.4 7.9 7.8 0.81 9.9 4.4 1.7 1 1 1 2 2 2 0 Apc13p protein Paramyxo_C PF01692.18 GBG60112.1 - 0.96 8.8 6.9 0.085 12.2 1.7 1.9 2 1 0 2 2 2 0 Paramyxovirus non-structural protein C DUF3089 PF11288.8 GBG60113.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Asp_protease_2 PF13650.6 GBG60115.1 - 0.0003 21.4 0.0 0.00073 20.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60115.1 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60115.1 - 0.011 16.3 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60115.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG60116.1 - 0.018 15.3 3.5 1.8 8.9 0.0 3.5 3 1 0 3 3 3 0 Retrotransposon gag protein CCDC92 PF14916.6 GBG60116.1 - 0.029 14.1 7.2 0.031 14.0 1.8 2.8 3 0 0 3 3 3 0 Coiled-coil domain of unknown function AP1AR PF15745.5 GBG60116.1 - 1.2 8.8 7.8 2.2 7.8 7.8 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein ADIP PF11559.8 GBG60116.1 - 1.6 8.8 14.8 2.8 8.0 0.1 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding FUSC PF04632.12 GBG60116.1 - 2.1 6.8 14.4 1.1 7.8 12.5 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Apolipoprotein PF01442.18 GBG60116.1 - 6.8 6.5 20.5 8.8 6.1 19.2 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain RT_RNaseH_2 PF17919.1 GBG60117.1 - 1.6e-28 98.7 0.0 2.8e-13 49.7 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60117.1 - 2.1e-28 98.2 3.7 1.9e-15 56.7 0.1 3.0 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG60117.1 - 7.9e-28 97.5 0.0 1.8e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60117.1 - 1.4e-27 96.0 0.0 3.8e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG60117.1 - 3e-10 39.8 0.0 7.1e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG60117.1 - 3.5e-08 33.7 0.0 2.6e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG60117.1 - 0.0012 19.0 0.7 0.38 11.0 0.0 3.0 2 0 0 2 2 2 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG60117.1 - 0.27 11.5 2.0 1.6 9.0 0.0 3.0 2 0 0 2 2 2 0 Retrotransposon gag protein DUF4407 PF14362.6 GBG60117.1 - 0.36 10.2 10.8 0.49 9.7 6.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Toprim_N PF08275.11 GBG60118.1 - 1.2e-07 31.8 7.5 26 4.9 0.0 8.9 1 1 7 9 9 9 0 DNA primase catalytic core, N-terminal domain SH3_19 PF18597.1 GBG60118.1 - 3.9e-06 26.6 49.9 12 5.8 0.1 12.5 13 0 0 13 13 13 3 Myosin X N-terminal SH3 domain RTA1 PF04479.13 GBG60118.1 - 8.1e-05 22.3 19.9 41 3.7 0.1 10.4 1 1 12 13 13 13 0 RTA1 like protein PapC_C PF13953.6 GBG60118.1 - 0.00021 21.0 33.4 6.7 6.6 0.6 9.2 1 1 10 11 11 11 6 PapC C-terminal domain ImpE PF07024.13 GBG60118.1 - 0.00054 20.0 21.7 5.2 7.2 0.1 8.6 1 1 7 10 10 10 1 ImpE protein DCR PF14047.6 GBG60118.1 - 0.00079 19.6 7.8 26 5.1 0.0 6.6 3 3 6 9 9 9 0 Dppa2/4 conserved region Methyltransf_1N PF02870.15 GBG60118.1 - 0.003 18.3 10.3 72 4.3 0.1 6.8 2 2 3 6 6 6 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain ATP_transf PF09830.9 GBG60118.1 - 0.65 10.2 14.4 1.1e+02 3.1 0.6 7.6 3 3 4 7 7 7 0 ATP adenylyltransferase DdrB PF12747.7 GBG60118.1 - 8 6.3 21.8 18 5.2 0.6 6.3 1 1 10 11 11 11 0 DdrB-like protein RVT_1 PF00078.27 GBG60119.1 - 1.1e-21 77.4 0.1 2.7e-21 76.1 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG60119.1 - 1.7e-06 27.8 0.0 3.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60119.1 - 1.3e-05 25.8 0.0 4.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60119.1 - 2.6e-05 24.7 0.0 8.8e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG60119.1 - 0.00044 20.5 4.0 0.00064 20.0 0.0 3.1 2 1 0 2 2 2 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG60119.1 - 0.0014 19.2 1.6 0.0014 19.2 1.6 2.6 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Asp_protease PF09668.10 GBG60119.1 - 0.0027 17.5 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease NPV_P10 PF05531.12 GBG60119.1 - 0.32 11.5 1.1 2.6 8.6 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SPARC_Ca_bdg PF10591.9 GBG60119.1 - 0.58 10.5 3.1 0.71 10.2 1.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region LRR_9 PF14580.6 GBG60121.1 - 4.5e-10 39.3 0.4 6.7e-10 38.7 0.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 GBG60121.1 - 2.2e-08 34.2 0.1 0.001 19.4 0.0 3.1 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG60121.1 - 8.1e-07 28.7 0.1 1.8e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat Bromodomain PF00439.25 GBG60121.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Bromodomain RVT_1 PF00078.27 GBG60122.1 - 5.3e-76 255.0 9.1 7.1e-30 104.2 0.1 4.9 5 0 0 5 5 5 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60122.1 - 2.2e-75 249.0 0.0 1.9e-27 95.2 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60122.1 - 5.2e-65 216.3 0.9 4.1e-27 94.5 0.0 4.8 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60122.1 - 3.5e-31 107.1 4.3 4.6e-18 65.1 0.4 3.0 2 0 0 2 2 2 2 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG60122.1 - 3.2e-22 78.9 0.0 3.2e-07 30.8 0.0 5.3 4 1 0 4 4 4 3 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60122.1 - 6.8e-19 68.3 0.0 3.1e-05 24.5 0.0 5.2 4 1 0 4 4 4 3 Aspartyl protease Pkinase_Tyr PF07714.17 GBG60122.1 - 5.6e-18 65.2 0.0 5.1e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 GBG60122.1 - 9.9e-16 57.3 33.2 1.4e-06 27.9 2.3 4.6 3 1 1 4 4 4 4 Leucine rich repeat RVP_2 PF08284.11 GBG60122.1 - 1.4e-14 54.0 0.0 5.5e-05 23.0 0.0 4.7 4 1 0 4 4 4 3 Retroviral aspartyl protease Pkinase PF00069.25 GBG60122.1 - 1.3e-11 44.4 0.1 8.2e-08 31.9 0.1 3.2 2 1 0 2 2 2 2 Protein kinase domain DUF1758 PF05585.12 GBG60122.1 - 5.3e-11 42.6 0.1 0.0073 16.1 0.0 3.6 3 0 0 3 3 3 3 Putative peptidase (DUF1758) LRR_4 PF12799.7 GBG60122.1 - 8.1e-10 38.8 33.1 0.00039 20.7 2.4 6.2 2 2 4 7 7 7 5 Leucine Rich repeats (2 copies) Asp_protease PF09668.10 GBG60122.1 - 2.6e-09 36.9 0.6 0.12 12.2 0.0 5.1 5 1 0 5 5 5 3 Aspartyl protease Retrotrans_gag PF03732.17 GBG60122.1 - 1e-06 28.9 15.3 0.055 13.7 0.1 6.0 6 0 0 6 6 4 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG60122.1 - 0.004 17.3 0.3 0.11 12.7 0.1 3.0 2 0 0 2 2 2 1 H2C2 zinc finger Chromo PF00385.24 GBG60122.1 - 0.078 12.9 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain HIP1_clath_bdg PF16515.5 GBG60122.1 - 3.3 8.4 20.5 1.6 9.4 8.5 3.8 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 IDO PF01231.18 GBG60123.1 - 0.091 11.5 0.4 0.13 11.1 0.4 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase SseC PF04888.12 GBG60123.1 - 0.1 12.1 0.7 0.16 11.6 0.7 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF2828 PF11443.8 GBG60123.1 - 0.12 10.4 0.1 0.17 10.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 GBG60123.1 - 0.4 9.4 0.4 0.38 9.5 0.4 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 GBG60123.1 - 1 9.1 2.0 1.6 8.5 2.0 1.2 1 0 0 1 1 1 0 Connexin Nop14 PF04147.12 GBG60125.1 - 1.1 7.4 19.6 1.7 6.8 19.6 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG60125.1 - 6 5.5 7.9 7.6 5.2 7.9 1.2 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GBG60125.1 - 9.5 5.4 25.8 0.14 11.5 18.4 1.5 2 0 0 2 2 2 0 BUD22 ATE_N PF04376.13 GBG60127.1 - 0.017 15.5 0.4 0.16 12.4 0.0 2.5 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus zf-CCHC PF00098.23 GBG60127.1 - 0.49 10.6 1.8 1.1 9.5 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG60128.1 - 1.4e-35 121.7 0.2 2.4e-22 79.2 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60128.1 - 5.2e-34 116.3 0.0 1.6e-25 89.1 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60128.1 - 1.7e-32 112.1 0.0 2.4e-16 60.0 0.0 3.2 3 0 0 3 3 3 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG60128.1 - 4.6e-31 106.7 3.0 1.3e-14 54.0 0.7 3.8 3 0 0 3 3 3 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG60128.1 - 1.5e-19 70.4 0.0 3.1e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG60128.1 - 1.6e-06 28.2 0.0 0.024 14.9 0.1 2.8 2 0 0 2 2 2 2 H2C2 zinc finger Chromo PF00385.24 GBG60128.1 - 3e-05 23.8 0.1 0.018 14.9 0.0 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 GBG60128.1 - 0.0027 17.4 0.0 2.6 7.9 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain Retrotrans_gag PF03732.17 GBG60128.1 - 0.022 15.1 0.1 0.09 13.1 0.1 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein Filament PF00038.21 GBG60128.1 - 0.6 9.6 8.2 4.9 6.6 0.0 3.7 4 0 0 4 4 4 0 Intermediate filament protein RT_RNaseH_2 PF17919.1 GBG60129.1 - 1.1e-52 176.2 0.0 3.3e-31 107.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60129.1 - 9.8e-39 131.9 0.1 4.2e-27 94.5 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60129.1 - 1.9e-17 63.5 0.2 1.2e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60129.1 - 1.1e-10 41.4 0.0 2.8e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG60129.1 - 1.1e-06 28.5 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60129.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease CCDC85 PF10226.9 GBG60129.1 - 0.031 13.9 0.4 0.079 12.6 0.4 1.7 1 0 0 1 1 1 0 CCDC85 family Asp_protease_2 PF13650.6 GBG60129.1 - 0.036 14.7 0.0 0.098 13.3 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease eIF-1a PF01176.19 GBG60129.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 bZIP_2 PF07716.15 GBG60129.1 - 4.8 7.3 10.0 2.8 8.1 3.8 2.6 2 0 0 2 2 2 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 GBG60129.1 - 5.4 7.3 7.7 0.34 11.2 0.8 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain RVP_2 PF08284.11 GBG60130.1 - 5.4e-07 29.4 0.0 9.1e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60130.1 - 7.7e-07 29.6 0.0 1.4e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60130.1 - 1.2e-06 29.1 0.0 2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60130.1 - 0.0001 22.1 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG60131.1 - 1.2e-17 63.7 0.0 3.9e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60131.1 - 1.8e-09 37.8 0.0 1e-08 35.4 0.0 2.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60131.1 - 0.0088 15.6 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG60131.1 - 0.052 13.8 0.1 0.052 13.8 0.1 3.3 4 1 1 5 5 5 0 Retrotransposon gag protein NPV_P10 PF05531.12 GBG60131.1 - 0.76 10.3 4.2 9.2 6.8 4.2 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein H_PPase PF03030.16 GBG60132.1 - 2.6e-202 674.0 23.6 3.1e-202 673.7 23.6 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase H_PPase PF03030.16 GBG60133.1 - 1.8e-77 261.5 9.0 2e-77 261.4 9.0 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Hol_Tox PF16935.5 GBG60133.1 - 0.23 11.6 2.3 0.26 11.4 0.3 2.2 1 1 1 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) Tetraspanin PF00335.20 GBG60133.1 - 0.6 9.8 3.3 1.1 8.9 3.3 1.5 1 0 0 1 1 1 0 Tetraspanin family DUF5518 PF17647.1 GBG60133.1 - 6.3 7.0 20.3 1 9.5 4.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5518) RT_RNaseH_2 PF17919.1 GBG60135.1 - 6.8e-33 112.7 0.0 1.5e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60135.1 - 2.6e-28 98.4 0.1 5e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60135.1 - 3.5e-28 98.6 0.1 6.9e-28 97.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60136.1 - 6.2e-29 100.0 0.0 1.3e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60136.1 - 1.7e-28 98.9 0.1 4e-28 97.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG60136.1 - 0.067 12.8 0.1 0.067 12.8 0.1 2.7 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG60136.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TadF PF16964.5 GBG60136.1 - 1.3 8.8 3.6 2.1 8.1 3.6 1.3 1 0 0 1 1 1 0 Putative tight adherence pilin protein F Nop14 PF04147.12 GBG60136.1 - 7.2 4.7 25.2 10 4.2 25.2 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 GBG60137.1 - 0.015 15.4 6.8 0.015 15.4 6.8 1.9 2 0 0 2 2 2 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GBG60137.1 - 0.11 12.2 3.5 0.24 11.1 3.5 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 GBG60137.1 - 0.53 10.3 2.4 1.1 9.3 2.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 GBG60137.1 - 2.3 6.4 4.3 3.5 5.8 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein H_PPase PF03030.16 GBG60138.1 - 7.9e-42 143.7 2.0 1.1e-41 143.2 2.0 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Integrase_H2C2 PF17921.1 GBG60138.1 - 2.3e-37 126.9 2.5 1e-17 64.0 0.4 4.0 4 0 0 4 4 4 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG60138.1 - 8.2e-37 126.9 0.4 1.7e-23 83.3 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60138.1 - 8.3e-25 86.7 0.0 2.8e-24 85.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60138.1 - 8.1e-24 83.9 0.0 2.1e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60138.1 - 1e-23 83.8 0.0 8e-14 51.9 0.0 3.1 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG60138.1 - 8.2e-09 35.5 0.0 0.00013 22.1 0.0 2.8 2 0 0 2 2 2 2 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG60138.1 - 2.3e-07 31.4 0.0 0.00031 21.3 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG60138.1 - 4.3e-07 30.4 0.0 0.0074 16.8 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG60138.1 - 9.7e-06 25.4 0.0 0.00024 20.9 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60138.1 - 0.00022 21.0 0.0 0.97 9.2 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease Retrotrans_gag PF03732.17 GBG60138.1 - 0.00077 19.7 0.0 0.0051 17.0 0.0 2.5 1 0 0 1 1 1 1 Retrotransposon gag protein rve_3 PF13683.6 GBG60138.1 - 0.14 12.0 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Integrase core domain LPP PF04728.13 GBG60138.1 - 2.3 8.7 3.9 6.1 7.3 0.2 3.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF659 PF04937.15 GBG60139.1 - 7.1e-26 90.9 0.8 2.2e-25 89.3 0.8 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Rgp1 PF08737.10 GBG60139.1 - 0.66 9.1 8.0 0.95 8.6 8.0 1.2 1 0 0 1 1 1 0 Rgp1 NHase_alpha PF02979.16 GBG60139.1 - 1.2 8.4 0.0 1.2 8.4 0.0 3.0 4 0 0 4 4 4 0 Nitrile hydratase, alpha chain RR_TM4-6 PF06459.12 GBG60139.1 - 2.6 7.8 27.4 0.9 9.3 24.9 1.5 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 GBG60139.1 - 4.3 7.4 6.4 8.6 6.4 6.4 1.5 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 GBG60139.1 - 6.2 5.7 7.5 13 4.6 7.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) VIR_N PF15912.5 GBG60139.1 - 7.1 6.1 14.0 12 5.4 14.0 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal V_ATPase_I PF01496.19 GBG60139.1 - 7.3 4.4 12.1 12 3.6 12.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myb_DNA-bind_4 PF13837.6 GBG60140.1 - 4e-07 30.3 2.7 4e-07 30.3 2.7 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG60140.1 - 0.00074 19.7 0.5 0.0018 18.5 0.5 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG60140.1 - 0.0013 19.0 0.9 0.0013 19.0 0.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG60140.1 - 0.003 17.6 1.1 0.003 17.6 1.1 2.7 4 0 0 4 4 4 1 Myb/SANT-like DNA-binding domain Nop53 PF07767.11 GBG60140.1 - 0.14 11.5 3.1 0.3 10.5 3.1 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Myb_DNA-binding PF00249.31 GBG60140.1 - 0.21 11.8 0.2 0.21 11.8 0.2 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG60141.1 - 1.8e-28 99.2 0.0 2.5e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60141.1 - 2.7e-15 56.5 0.0 4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG60141.1 - 0.00028 20.6 0.1 0.77 9.4 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain DUF659 PF04937.15 GBG60142.1 - 1.1e-29 103.3 0.1 1.6e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Peptidase_C48 PF02902.19 GBG60143.1 - 0.00036 20.4 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF659 PF04937.15 GBG60144.1 - 2.4e-23 82.7 0.0 4.1e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG60145.1 - 0.00051 20.0 1.5 0.0012 18.8 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF659 PF04937.15 GBG60146.1 - 1e-09 38.5 0.0 2.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60146.1 - 2.8e-07 30.2 0.1 6.1e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nop14 PF04147.12 GBG60147.1 - 0.2 9.9 20.5 0.25 9.5 20.5 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG60147.1 - 0.39 9.1 23.4 0.53 8.7 23.4 1.2 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG60147.1 - 4.1 6.7 31.1 0.028 13.9 22.6 1.7 2 0 0 2 2 2 0 SDA1 Cnd2 PF05786.14 GBG60147.1 - 4.3 5.9 19.0 7.1 5.1 19.0 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 BUD22 PF09073.10 GBG60150.1 - 1.4 8.2 10.0 1.8 7.8 10.0 1.2 1 0 0 1 1 1 0 BUD22 RT_RNaseH_2 PF17919.1 GBG60152.1 - 1e-34 118.5 0.0 2.6e-33 114.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60152.1 - 2.7e-29 101.5 0.1 9.4e-29 99.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60152.1 - 1.1e-16 60.7 0.9 1.6e-16 60.1 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG60152.1 - 0.025 14.8 0.0 0.078 13.2 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG60152.1 - 7.2 6.7 13.2 0.042 13.8 4.4 1.8 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH PF17917.1 GBG60153.1 - 2.7e-23 82.3 0.0 6.2e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60153.1 - 8.3e-23 80.3 0.0 2.1e-22 79.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60153.1 - 3.8e-12 46.1 0.0 8.6e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG60153.1 - 5.3e-08 32.7 0.0 1.9e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60153.1 - 2.6e-06 28.0 0.0 7.2e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease NCBP3 PF10309.9 GBG60153.1 - 0.015 15.1 0.2 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Nuclear cap-binding protein subunit 3 gag-asp_proteas PF13975.6 GBG60153.1 - 0.016 15.7 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Integrin_b_cyt PF08725.11 GBG60153.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain BTB_2 PF02214.22 GBG60154.1 - 1.2e-05 25.5 0.1 2.2e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Tir_receptor_N PF07490.11 GBG60154.1 - 0.045 13.6 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus ArfGap PF01412.18 GBG60154.1 - 2.9 8.0 10.9 2.4 8.2 4.3 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Sporozoite_P67 PF05642.11 GBG60155.1 - 0.59 8.2 2.5 0.86 7.6 2.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RT_RNaseH PF17917.1 GBG60157.1 - 1.3e-30 105.8 0.1 6e-30 103.6 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60157.1 - 6e-29 100.0 0.0 2.3e-28 98.2 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60157.1 - 6.6e-29 101.0 0.1 1.1e-28 100.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60157.1 - 1e-15 57.6 1.0 4.9e-15 55.4 0.5 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG60157.1 - 1.6e-11 44.5 0.1 1.5e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG60157.1 - 6.8e-07 29.0 0.2 1.9e-06 27.6 0.2 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG60158.1 - 3.6e-23 81.5 0.0 9.3e-23 80.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60158.1 - 1.1e-21 77.1 0.0 2.7e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60158.1 - 1.3e-18 67.4 0.1 3e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60158.1 - 6.9e-17 61.3 0.4 1.9e-16 59.9 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG60158.1 - 0.0024 18.1 0.3 0.013 15.7 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG60159.1 - 2.8e-18 65.8 0.1 5e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60159.1 - 1.3e-15 57.6 0.0 2.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG60161.1 - 3e-30 104.2 0.0 7.1e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60161.1 - 2.2e-28 98.6 0.0 7e-28 97.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60161.1 - 2.1e-13 50.2 0.1 5.1e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG60161.1 - 1.8e-07 31.0 0.0 3.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60161.1 - 0.00028 21.4 0.0 0.00073 20.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60161.1 - 0.00052 20.5 0.2 0.0022 18.5 0.0 2.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG60161.1 - 0.0026 17.6 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG60161.1 - 0.022 14.3 0.2 0.39 10.2 0.1 2.3 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) ADP_ribosyl_GH PF03747.14 GBG60161.1 - 0.022 14.5 6.5 9.5 5.8 6.9 3.7 3 1 0 3 3 3 0 ADP-ribosylglycohydrolase DUF1152 PF06626.12 GBG60161.1 - 0.045 13.0 0.3 0.24 10.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1152) Phage_GPO PF05929.11 GBG60161.1 - 0.16 11.6 0.0 0.16 11.6 0.0 3.2 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG60162.1 - 1.8e-23 82.5 0.0 3.6e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60162.1 - 6.5e-20 71.4 0.0 1.8e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60162.1 - 1.9e-09 37.7 0.1 1.3e-08 35.1 0.0 2.5 3 1 1 4 4 4 1 Integrase core domain rve_3 PF13683.6 GBG60162.1 - 0.014 15.1 0.0 0.08 12.7 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG60163.1 - 1.7e-15 56.9 0.0 3.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60163.1 - 2.1e-15 57.0 0.0 4.2e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG60163.1 - 5.1e-14 52.4 0.0 2.4e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60163.1 - 9.2e-13 48.1 0.0 2.2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG60163.1 - 0.00031 20.3 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG60163.1 - 0.0029 17.4 0.0 0.013 15.3 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG60164.1 - 1.3e-06 28.1 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG60164.1 - 0.0011 19.5 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG60164.1 - 0.026 14.9 0.0 0.076 13.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 GBG60165.1 - 6.5e-11 42.5 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG60165.1 - 0.008 15.9 0.0 0.032 14.0 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG60165.1 - 0.043 14.1 0.1 0.18 12.1 0.1 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein rve PF00665.26 GBG60166.1 - 3.5e-15 56.2 0.0 9.3e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG60166.1 - 7.3e-06 26.2 0.1 3.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60166.1 - 5.5e-05 23.1 0.1 0.00012 22.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Thioredoxin_13 PF18401.1 GBG60166.1 - 0.16 11.9 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain RVT_1 PF00078.27 GBG60167.1 - 2.8e-29 102.2 0.0 4.7e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60167.1 - 1e-27 96.1 0.0 6.5e-14 51.8 0.0 3.3 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60167.1 - 3.2e-18 65.9 0.0 2e-17 63.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60167.1 - 5.1e-10 39.6 0.1 1.8e-09 37.8 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG60167.1 - 5.7e-08 32.8 0.3 2.4e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG60167.1 - 0.036 14.7 0.0 0.072 13.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG60168.1 - 3.9e-24 85.1 0.0 6.4e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Chromo PF00385.24 GBG60168.1 - 1e-11 44.6 0.0 2.2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Plant_tran PF04827.14 GBG60168.1 - 1.8e-10 40.8 0.0 3.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG60168.1 - 0.00038 20.2 0.1 0.0023 17.6 0.0 2.3 3 0 0 3 3 3 1 Transposase DDE domain Asp_protease_2 PF13650.6 GBG60168.1 - 0.027 15.1 0.1 0.098 13.3 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease RVP_2 PF08284.11 GBG60169.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60169.1 - 0.16 12.6 0.1 0.33 11.6 0.1 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60169.1 - 0.19 11.5 0.1 0.33 10.7 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Nop14 PF04147.12 GBG60169.1 - 6.9 4.8 31.2 11 4.1 31.2 1.2 1 0 0 1 1 1 0 Nop14-like family Retrotrans_gag PF03732.17 GBG60170.1 - 0.0045 17.2 0.7 0.0094 16.2 0.7 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG60170.1 - 0.047 13.5 0.8 0.072 12.9 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG60171.1 - 2.8e-10 40.5 0.6 5e-10 39.6 0.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG60171.1 - 0.0033 17.7 0.1 0.0064 16.8 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF5000 PF16391.5 GBG60171.1 - 0.075 13.2 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function Myb_DNA-bind_5 PF13873.6 GBG60171.1 - 0.51 10.4 2.6 0.92 9.6 2.6 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MSA-2c PF12238.8 GBG60171.1 - 6.2 6.8 6.3 10 6.1 6.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c RT_RNaseH_2 PF17919.1 GBG60172.1 - 5.1e-23 81.0 0.0 9.8e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60172.1 - 2.8e-21 75.8 0.0 5.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG60176.1 - 2.9e-12 47.1 0.0 2.9e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG60176.1 - 5.7e-12 46.0 0.0 6.6e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG60176.1 - 1.8e-09 37.8 0.0 3.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG60176.1 - 1e-08 35.0 0.0 1.7e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60176.1 - 2.9e-08 33.5 0.4 0.0031 17.3 0.1 3.3 3 1 0 3 3 3 2 Aspartyl protease RVP PF00077.20 GBG60176.1 - 1.3e-05 25.4 0.0 0.0061 16.8 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease DUF1758 PF05585.12 GBG60176.1 - 0.004 17.0 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) rve_3 PF13683.6 GBG60176.1 - 0.014 15.2 0.2 0.055 13.2 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain Integrase_H2C2 PF17921.1 GBG60177.1 - 1.9e-16 59.9 1.4 2.6e-16 59.5 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG60177.1 - 8.5e-16 58.1 0.0 1.8e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60177.1 - 1.3e-11 44.4 0.0 5.1e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60177.1 - 0.026 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Cytotoxic PF09000.10 GBG60177.1 - 0.11 12.9 1.0 0.24 11.8 0.3 1.9 2 0 0 2 2 2 0 Cytotoxic OTCace PF00185.24 GBG60177.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Retrotrans_gag PF03732.17 GBG60177.1 - 0.14 12.4 0.1 0.38 11.0 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG60177.1 - 0.15 12.3 0.4 0.32 11.3 0.4 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Pkinase PF00069.25 GBG60178.1 - 3.9e-58 196.9 0.0 8.5e-58 195.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG60178.1 - 5.2e-44 150.5 0.0 7.9e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG60178.1 - 8.8e-06 24.7 0.1 2.3e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 GBG60178.1 - 0.00025 20.1 0.1 0.0019 17.2 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 GBG60178.1 - 0.0023 17.3 0.0 0.0061 15.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 GBG60178.1 - 0.0094 15.0 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 DUF2205 PF10224.9 GBG60178.1 - 0.076 13.0 2.9 0.96 9.5 0.5 2.5 2 0 0 2 2 2 0 Short coiled-coil protein APH PF01636.23 GBG60178.1 - 0.08 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GBG60178.1 - 0.14 11.5 0.1 0.49 9.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RT_RNaseH PF17917.1 GBG60179.1 - 5.8e-20 71.5 0.0 1.4e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60179.1 - 4.9e-19 68.2 0.0 8.5e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG60179.1 - 0.01 16.1 0.2 0.021 15.1 0.2 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG60179.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Drc1-Sld2 PF11719.8 GBG60181.1 - 0.0064 16.1 16.0 0.0064 16.1 16.0 4.1 4 0 0 4 4 4 1 DNA replication and checkpoint protein CRT-like PF08627.10 GBG60182.1 - 7e-45 153.4 10.2 9.7e-45 153.0 10.2 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like RVT_1 PF00078.27 GBG60182.1 - 3.6e-39 134.6 0.0 9.6e-35 120.1 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60182.1 - 1.2e-28 99.5 0.3 1.4e-27 96.0 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60182.1 - 9e-27 93.0 0.1 6.7e-26 90.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60182.1 - 3.8e-17 62.1 0.3 9.5e-17 60.9 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60182.1 - 6.1e-14 52.2 0.0 1.5e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG60182.1 - 0.00029 21.0 0.3 0.0017 18.5 0.1 2.5 2 0 0 2 2 2 1 H2C2 zinc finger Chromo PF00385.24 GBG60182.1 - 0.091 12.7 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain SpoIIIAC PF06686.11 GBG60182.1 - 0.37 11.0 3.1 1.6 9.0 3.1 2.1 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family SLC35F PF06027.12 GBG60182.1 - 2.4 7.6 7.1 0.16 11.4 2.0 1.5 2 0 0 2 2 2 0 Solute carrier family 35 RVT_1 PF00078.27 GBG60183.1 - 2.5e-36 125.3 0.0 4.7e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60183.1 - 2.2e-30 104.6 0.0 5.6e-30 103.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60183.1 - 2.8e-30 104.7 0.0 7.1e-30 103.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG60183.1 - 1.8e-06 27.8 0.0 4.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60183.1 - 6.7e-06 26.7 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60183.1 - 0.0002 21.8 0.0 0.00063 20.2 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG60183.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF919 PF06034.11 GBG60183.1 - 0.036 13.9 4.0 0.043 13.7 0.9 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) THUMP PF02926.17 GBG60183.1 - 0.33 11.0 4.0 1.1 9.3 3.5 2.1 2 0 0 2 2 2 0 THUMP domain Phage_GPO PF05929.11 GBG60183.1 - 5.2 6.6 9.0 0.27 10.8 0.1 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Integrase_H2C2 PF17921.1 GBG60184.1 - 1.5e-17 63.4 0.1 3.2e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG60184.1 - 0.0015 18.3 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG60184.1 - 0.0039 17.4 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG60184.1 - 0.018 15.2 0.1 0.073 13.3 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain Retrotrans_gag PF03732.17 GBG60184.1 - 0.062 13.6 0.2 0.062 13.6 0.2 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG60185.1 - 5.6e-26 90.5 0.0 2.1e-25 88.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60185.1 - 1.1e-25 90.5 0.2 3.1e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60185.1 - 1e-24 86.8 0.0 2.8e-24 85.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60185.1 - 1.2e-06 29.0 0.0 4e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60185.1 - 1.7e-06 28.6 0.0 4.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60185.1 - 2e-05 24.4 0.0 4.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG60185.1 - 0.00014 22.1 0.3 0.062 13.6 0.0 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG60185.1 - 0.00044 20.0 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG60186.1 - 2.4e-26 92.6 0.2 4.7e-26 91.7 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60186.1 - 2.2e-18 66.1 0.0 2.8e-14 53.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60186.1 - 7.1e-08 32.7 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60186.1 - 2.7e-06 27.4 0.0 5.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60186.1 - 0.00053 20.2 0.1 0.0015 18.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG60188.1 - 1.5e-17 63.4 0.4 3.5e-17 62.3 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60188.1 - 4.6e-13 49.4 0.0 1.4e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG60188.1 - 0.0002 21.5 0.0 0.00047 20.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Apc13p PF05839.11 GBG60188.1 - 0.15 12.3 1.0 0.49 10.6 1.0 1.9 1 0 0 1 1 1 0 Apc13p protein RVT_1 PF00078.27 GBG60189.1 - 8.5e-49 166.0 0.3 6e-35 120.8 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60189.1 - 6.1e-42 141.7 0.0 1.5e-24 85.9 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60189.1 - 1.4e-37 128.2 0.0 2.6e-27 95.2 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG60189.1 - 3.5e-09 36.5 0.0 4.3e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60189.1 - 6e-06 26.8 0.0 6.6e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60189.1 - 0.00013 22.5 0.1 0.00087 19.8 0.0 2.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF4392 PF14336.6 GBG60189.1 - 0.0086 15.6 0.0 3.3 7.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4392) DUF1758 PF05585.12 GBG60189.1 - 0.018 14.8 0.0 0.064 13.0 0.0 1.9 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG60189.1 - 0.059 13.2 0.0 0.29 10.9 0.0 2.1 2 1 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG60190.1 - 2.8e-30 104.3 0.0 6.2e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60190.1 - 2.2e-24 85.7 0.0 6.2e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60190.1 - 0.00018 22.0 0.0 0.00074 20.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG60190.1 - 0.0022 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60190.1 - 0.012 16.3 0.0 0.027 15.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG60190.1 - 0.024 14.1 0.2 0.045 13.3 0.2 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG60190.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG60190.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG60190.1 - 0.42 10.2 0.0 0.42 10.2 0.0 2.8 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF913 PF06025.12 GBG60191.1 - 0.016 14.2 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 GBG60191.1 - 0.022 14.2 12.0 0.029 13.8 12.0 1.1 1 0 0 1 1 1 0 SDA1 Tim54 PF11711.8 GBG60191.1 - 0.042 12.6 0.5 0.056 12.2 0.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.16 GBG60191.1 - 0.13 11.5 2.5 0.18 11.0 2.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Trypan_PARP PF05887.11 GBG60191.1 - 0.18 11.8 15.0 0.27 11.2 15.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RPN2_C PF18004.1 GBG60191.1 - 0.5 10.3 4.5 0.76 9.7 4.5 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 GBG60191.1 - 1.1 7.4 16.0 1.5 6.9 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 GBG60191.1 - 3.1 7.1 4.7 13 5.0 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4746 PF15928.5 GBG60191.1 - 4.7 6.5 12.8 8.9 5.6 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RT_RNaseH_2 PF17919.1 GBG60192.1 - 1.9e-31 108.1 0.0 3.3e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60192.1 - 1.5e-28 99.1 0.0 2.7e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60192.1 - 1.9e-21 76.6 0.0 4e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG60192.1 - 0.053 13.1 0.1 0.087 12.4 0.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG60193.1 - 5e-58 193.3 0.0 7.7e-30 102.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60193.1 - 1e-50 172.3 0.7 3.3e-33 115.1 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60193.1 - 3.7e-41 139.7 0.1 2e-24 85.9 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60193.1 - 3.8e-17 62.1 0.0 3.8e-17 62.1 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG60193.1 - 1.4e-09 38.2 0.0 3.4e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG60193.1 - 0.021 15.1 0.0 0.085 13.1 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger DUF5095 PF17016.5 GBG60193.1 - 0.2 11.3 1.3 4.6 6.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) gag-asp_proteas PF13975.6 GBG60194.1 - 1.1e-07 32.3 0.0 2.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60194.1 - 1.5e-05 25.5 0.0 2.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60194.1 - 0.0043 16.8 0.1 0.0073 16.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG60194.1 - 0.057 13.7 0.0 0.19 12.1 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease CPSF100_C PF13299.6 GBG60194.1 - 0.24 11.6 2.6 0.44 10.7 2.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal VIR_N PF15912.5 GBG60194.1 - 0.52 9.9 5.2 0.89 9.1 5.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal RXLR PF16810.5 GBG60194.1 - 1.3 9.5 3.7 23 5.4 0.8 2.2 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity CDC45 PF02724.14 GBG60194.1 - 1.5 7.0 5.8 2 6.6 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 GBG60194.1 - 2.1 8.0 6.4 5.7 6.6 6.4 1.7 1 0 0 1 1 1 0 FAM176 family PTPRCAP PF15713.5 GBG60194.1 - 3.7 7.8 12.0 0.91 9.8 8.1 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RT_RNaseH PF17917.1 GBG60195.1 - 4.6e-24 84.7 0.0 8.5e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60195.1 - 4.6e-19 68.3 0.0 1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60195.1 - 1.3e-15 57.3 0.1 3.6e-15 55.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60195.1 - 3.7e-14 52.9 0.0 7.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG60195.1 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG60195.1 - 0.076 12.8 0.0 0.34 10.7 0.0 2.2 3 0 0 3 3 3 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG60196.1 - 4.6e-24 84.4 0.0 1.3e-23 82.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60196.1 - 5.1e-22 78.2 0.0 1.1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60196.1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60196.1 - 0.00095 19.2 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60196.1 - 0.0069 16.6 0.1 0.018 15.2 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG60196.1 - 0.044 13.7 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG60198.1 - 1.6e-28 99.8 0.1 2.6e-28 99.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG60198.1 - 0.003 17.8 0.1 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF659 PF04937.15 GBG60199.1 - 1.6e-36 125.4 0.0 4.4e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60199.1 - 9.7e-05 22.1 0.1 0.00023 20.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2HE PF16278.5 GBG60199.1 - 0.035 14.5 1.0 0.13 12.7 1.0 2.0 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Zw10 PF06248.13 GBG60200.1 - 1.8e-19 69.7 0.0 3.9e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 RVP_2 PF08284.11 GBG60200.1 - 4e-06 26.6 0.0 9.6e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60200.1 - 0.00025 21.6 0.0 0.00057 20.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60200.1 - 0.028 15.0 0.3 0.11 13.1 0.0 2.2 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60200.1 - 0.094 12.5 0.0 0.89 9.4 0.0 2.4 2 1 0 2 2 2 0 Aspartyl protease DUF1758 PF05585.12 GBG60200.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG60201.1 - 3.1e-32 111.9 0.0 5.5e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60201.1 - 1.2e-30 105.4 0.0 3.2e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60201.1 - 1.3e-29 102.5 0.0 2.5e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Zw10 PF06248.13 GBG60202.1 - 3.6e-22 78.7 2.0 1.1e-06 27.5 0.1 4.0 3 1 1 4 4 4 4 Centromere/kinetochore Zw10 TraT PF05818.12 GBG60202.1 - 0.073 12.7 1.5 8.1 6.1 0.1 2.3 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein JUPITER PF17054.5 GBG60202.1 - 1.2 8.5 5.3 9.3 5.6 0.8 2.1 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter RVT_1 PF00078.27 GBG60203.1 - 9.4e-32 110.3 0.1 1.6e-31 109.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60203.1 - 2.8e-23 81.8 0.0 5e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60203.1 - 6.6e-11 42.4 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60204.1 - 8e-20 71.3 0.2 1.5e-19 70.4 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG60204.1 - 1.7e-05 25.0 6.3 0.0058 16.9 0.2 4.2 3 1 0 3 3 3 2 Retrotransposon gag protein rve PF00665.26 GBG60204.1 - 0.0068 16.6 0.2 0.021 15.0 0.2 1.8 1 0 0 1 1 1 1 Integrase core domain FlxA PF14282.6 GBG60204.1 - 0.024 14.6 0.1 0.024 14.6 0.1 3.6 3 1 0 3 3 3 0 FlxA-like protein CLZ PF16526.5 GBG60204.1 - 7.8 6.9 8.3 1.9 8.9 1.0 3.3 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RVT_1 PF00078.27 GBG60205.1 - 6.1e-34 117.5 0.1 1.2e-33 116.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60205.1 - 5.5e-27 93.7 0.0 1.5e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60205.1 - 1.1e-26 93.1 0.0 2.5e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60205.1 - 5.5e-13 48.8 0.1 1.7e-12 47.2 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG60205.1 - 0.0081 16.4 0.1 0.048 13.9 0.1 2.5 1 0 0 1 1 1 1 H2C2 zinc finger DUF4392 PF14336.6 GBG60205.1 - 0.019 14.5 1.0 0.042 13.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Sirohm_synth_M PF14824.6 GBG60205.1 - 0.22 11.0 0.4 0.77 9.3 0.1 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central PA26 PF04636.13 GBG60205.1 - 1.2 8.0 11.4 2 7.3 11.4 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zw10 PF06248.13 GBG60206.1 - 0.00011 20.9 0.1 0.46 9.0 0.0 3.0 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 FSA_C PF10479.9 GBG60206.1 - 0.092 10.9 2.7 0.13 10.4 2.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1840 PF08895.11 GBG60206.1 - 7.1 7.0 10.1 2.8 8.3 0.8 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF1840) RT_RNaseH PF17917.1 GBG60207.1 - 2.4e-21 76.0 0.0 5.2e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60207.1 - 5.1e-20 71.4 0.0 1.3e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60207.1 - 4.7e-11 42.9 0.0 1.6e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG60207.1 - 2.3e-06 27.3 0.1 1.4e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sec8_exocyst PF04048.14 GBG60207.1 - 0.041 13.8 0.7 0.17 11.8 0.7 2.0 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain TerB_N PF13208.6 GBG60207.1 - 0.082 12.6 1.6 0.59 9.8 0.1 2.6 2 0 0 2 2 2 0 TerB N-terminal domain NAD_binding_10 PF13460.6 GBG60208.1 - 1.2e-29 103.5 0.0 2.8e-29 102.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GBG60208.1 - 2.7e-10 40.2 0.0 5.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GBG60208.1 - 2e-06 27.4 0.0 3.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GBG60208.1 - 0.00034 20.1 0.0 0.00058 19.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 GBG60208.1 - 0.002 18.4 0.0 0.0051 17.1 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 GBG60208.1 - 0.0021 17.2 0.0 0.0029 16.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 GBG60208.1 - 0.0074 16.7 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 GBG60208.1 - 0.013 14.7 0.1 0.2 10.8 0.1 2.2 2 0 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 GBG60208.1 - 0.035 13.5 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GBG60208.1 - 0.11 11.6 0.0 0.67 9.0 0.0 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.16 GBG60208.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAM91_C PF14648.6 GBG60210.1 - 0.84 8.4 3.0 1.4 7.6 3.0 1.3 1 0 0 1 1 1 0 FAM91 C-terminus Myb_DNA-bind_4 PF13837.6 GBG60212.1 - 2e-07 31.3 1.6 2.7e-07 30.8 1.6 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG60212.1 - 0.00035 20.8 2.6 0.00062 20.0 1.4 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG60212.1 - 0.0009 19.4 0.6 0.0012 19.0 0.6 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain FoP_duplication PF13865.6 GBG60212.1 - 0.031 14.8 7.0 0.031 14.8 7.0 1.9 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 RT_RNaseH PF17917.1 GBG60213.1 - 1e-21 77.2 0.1 2.7e-21 75.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase START PF01852.19 GBG60213.1 - 2.7e-15 56.3 0.0 5.8e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 START domain RT_RNaseH_2 PF17919.1 GBG60213.1 - 1.1e-12 47.8 0.0 2.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60213.1 - 9.4e-12 44.9 0.5 1.9e-11 43.9 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG60213.1 - 8.3e-09 35.6 0.0 2.4e-05 24.5 0.0 2.8 2 0 0 2 2 2 2 Retrotransposon gag protein rve PF00665.26 GBG60213.1 - 1.9e-06 28.1 0.0 5.1e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain VASt PF16016.5 GBG60215.1 - 9.1e-36 123.6 0.0 1.8e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain RT_RNaseH_2 PF17919.1 GBG60215.1 - 9.3e-31 105.8 0.0 2.2e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60215.1 - 2.9e-19 69.3 0.0 9.8e-19 67.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GRAM PF02893.20 GBG60215.1 - 2.9e-16 59.4 0.2 1e-12 48.0 0.0 2.5 2 0 0 2 2 2 2 GRAM domain TadF PF16964.5 GBG60215.1 - 0.13 12.0 0.4 0.78 9.5 1.4 1.8 2 0 0 2 2 2 0 Putative tight adherence pilin protein F DKCLD PF08068.12 GBG60216.1 - 2.1e-33 114.2 0.5 1.3e-31 108.5 0.6 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 GBG60216.1 - 1.5e-23 83.8 0.7 5.3e-20 72.3 0.6 4.3 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GBG60216.1 - 6.7e-22 77.4 0.3 1.6e-21 76.2 0.3 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 GBG60216.1 - 5.6e-21 74.3 2.9 5.6e-21 74.3 2.9 2.2 2 0 0 2 2 2 1 PUA domain UPF0113 PF03657.13 GBG60216.1 - 0.0083 16.4 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 UPF0113 PUA domain SWIM PF04434.17 GBG60217.1 - 1.2 8.9 3.1 4.1 7.2 3.1 1.9 1 1 0 1 1 1 0 SWIM zinc finger Hep_59 PF07052.11 GBG60218.1 - 2.9e-25 89.1 5.4 6.5e-25 87.9 5.4 1.6 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 FtsX_ECD PF18075.1 GBG60218.1 - 1.4 9.6 4.0 6.5 7.4 1.3 2.6 2 1 0 2 2 2 0 FtsX extracellular domain Helicase_C_2 PF13307.6 GBG60219.1 - 3.7e-37 128.1 0.1 9.7e-37 126.7 0.1 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain zf-CCHC_3 PF13917.6 GBG60219.1 - 0.077 13.0 0.3 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG60219.1 - 1 9.6 3.3 2 8.6 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Helicase_C_2 PF13307.6 GBG60220.1 - 6e-06 26.5 0.0 8.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 GBG60220.1 - 0.061 13.0 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Helical and beta-bridge domain Helicase_C_2 PF13307.6 GBG60221.1 - 7e-06 26.3 0.0 1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 GBG60221.1 - 0.049 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Helical and beta-bridge domain PIF1 PF05970.14 GBG60222.1 - 3e-99 332.6 0.0 7.6e-99 331.3 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase DEAD_2 PF06733.15 GBG60222.1 - 1e-39 136.0 11.7 1e-20 74.1 0.0 3.2 3 0 0 3 3 3 2 DEAD_2 Helitron_like_N PF14214.6 GBG60222.1 - 4.5e-30 105.3 0.0 8.9e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 GBG60222.1 - 3.4e-10 39.9 0.0 4.6e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 GBG60222.1 - 4.5e-06 26.8 0.0 0.0096 15.9 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG60222.1 - 0.00034 20.4 0.0 0.0062 16.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 GBG60222.1 - 0.00065 20.1 0.0 0.53 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain RT_RNaseH_2 PF17919.1 GBG60223.1 - 4.7e-25 87.5 0.0 7.9e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60223.1 - 7e-24 84.1 0.0 1.3e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60223.1 - 4.8e-11 42.6 0.1 8.1e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG60223.1 - 0.5 8.5 7.8 0.63 8.2 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG60223.1 - 1.2 8.5 10.4 1.8 7.9 10.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG60223.1 - 1.6 6.9 9.5 2.3 6.4 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein WRC PF08879.10 GBG60224.1 - 1.3e-54 181.7 53.4 4.2e-16 58.4 4.6 4.8 5 0 0 5 5 5 4 WRC zf-C3Hc3H PF13891.6 GBG60224.1 - 0.0012 19.2 23.9 0.77 10.2 0.9 4.6 4 0 0 4 4 4 4 Potential DNA-binding domain Gti1_Pac2 PF09729.9 GBG60224.1 - 3.7 7.6 10.5 0.68 10.0 2.9 3.1 3 0 0 3 3 3 0 Gti1/Pac2 family zf-BED PF02892.15 GBG60224.1 - 5.2 7.2 7.3 0.44 10.6 0.2 2.9 3 0 0 3 3 3 0 BED zinc finger GREB1 PF15782.5 GBG60225.1 - 2.9 4.9 10.3 3.5 4.6 10.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2981 PF11200.8 GBG60225.1 - 3.9 7.1 7.8 4.4 6.9 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Utp14 PF04615.13 GBG60225.1 - 4.8 5.6 12.9 6 5.3 12.9 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 GBG60225.1 - 6.5 5.2 21.5 8.6 4.8 21.5 1.1 1 0 0 1 1 1 0 Macoilin family RRN3 PF05327.11 GBG60226.1 - 2.6 6.5 12.7 0.13 10.8 4.5 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 zf-CCHC PF00098.23 GBG60226.1 - 9.3 6.5 6.1 0.66 10.2 0.6 2.0 2 0 0 2 2 2 0 Zinc knuckle Alg6_Alg8 PF03155.15 GBG60228.1 - 5.7e-139 464.2 6.9 8.5e-139 463.6 6.9 1.2 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DDE_Tnp_4 PF13359.6 GBG60228.1 - 0.00029 20.5 0.0 0.00069 19.3 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Chromo PF00385.24 GBG60229.1 - 1.1e-12 47.7 0.0 2.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG60229.1 - 3.4e-12 46.6 0.0 7.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF3523 PF12037.8 GBG60230.1 - 3.4e-106 354.5 33.1 4.8e-106 354.0 33.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 GBG60230.1 - 3.3e-24 85.8 0.2 1.3e-23 83.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GBG60230.1 - 1.3e-05 25.0 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG60230.1 - 0.00093 19.5 9.7 0.085 13.1 0.0 3.6 2 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 GBG60230.1 - 0.001 18.5 0.0 0.0026 17.2 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GBG60230.1 - 0.0027 17.7 3.2 0.025 14.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG60230.1 - 0.0027 18.1 11.7 0.0042 17.5 0.0 3.5 2 2 1 3 3 2 2 AAA ATPase domain Borrelia_P83 PF05262.11 GBG60230.1 - 0.0095 14.5 17.5 0.013 14.0 17.5 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein AAA_24 PF13479.6 GBG60230.1 - 0.012 15.3 1.2 0.032 13.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GBG60230.1 - 0.028 14.8 0.0 0.077 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 GBG60230.1 - 0.072 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 GBG60230.1 - 0.083 13.1 0.1 0.083 13.1 0.1 3.9 2 1 2 4 4 3 0 AAA domain AAA_33 PF13671.6 GBG60230.1 - 0.11 12.6 0.2 0.11 12.6 0.2 3.5 2 2 0 2 2 1 0 AAA domain AAA_18 PF13238.6 GBG60230.1 - 0.15 12.6 0.0 0.15 12.6 0.0 2.7 2 1 0 2 2 1 0 AAA domain Abhydrolase_8 PF06259.12 GBG60230.1 - 0.44 10.2 2.8 0.45 10.1 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase TFIIA PF03153.13 GBG60230.1 - 1.8 8.4 18.3 3.2 7.6 18.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4207 PF13904.6 GBG60230.1 - 2.3 7.8 31.6 4.5 6.9 31.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF5401 PF17380.2 GBG60230.1 - 3.6 5.5 44.4 5.4 5.0 44.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) PUB PF09409.10 GBG60231.1 - 3.5e-15 55.7 0.0 6.2e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 GBG60231.1 - 4.5e-07 30.0 0.0 9.2e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain MAP65_ASE1 PF03999.12 GBG60231.1 - 1.9 7.1 7.9 3 6.4 7.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) FAM104 PF15434.6 GBG60231.1 - 8.9 6.9 9.8 6.7 7.3 4.2 2.5 2 0 0 2 2 2 0 Family 104 adh_short PF00106.25 GBG60233.1 - 1.5e-25 89.8 0.0 2.4e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GBG60233.1 - 5.4e-22 78.5 0.0 3.1e-17 62.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GBG60233.1 - 0.0011 18.5 0.0 0.0039 16.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GBG60233.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 KR domain Pkinase_Tyr PF07714.17 GBG60234.1 - 1e-40 139.7 0.0 1.5e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG60234.1 - 4.9e-40 137.6 0.0 7.8e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 GBG60234.1 - 1.5e-10 40.7 0.1 8e-05 22.3 0.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GBG60234.1 - 3.7e-09 36.7 0.3 0.0035 17.7 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Malectin_like PF12819.7 GBG60234.1 - 0.0015 17.8 0.2 5.3 6.1 0.0 3.9 4 0 0 4 4 4 1 Malectin-like domain Malectin PF11721.8 GBG60234.1 - 0.0018 18.4 0.2 0.0069 16.5 0.0 2.1 3 0 0 3 3 3 1 Malectin domain LRR_6 PF13516.6 GBG60234.1 - 0.0035 17.3 0.5 47 4.4 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 GBG60234.1 - 0.018 15.5 4.4 21 6.1 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat TMIE PF16038.5 GBG60234.1 - 0.063 13.1 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 TMIE protein BNR PF02012.20 GBG60235.1 - 0.22 11.6 1.0 0.96 9.7 0.2 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat Phosphodiest PF01663.22 GBG60236.1 - 4.5e-39 135.1 0.0 7.3e-30 104.7 0.0 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GBG60236.1 - 0.0004 19.9 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 GBG60236.1 - 0.0063 15.2 0.0 0.0088 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF5010 PF16402.5 GBG60236.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) Metalloenzyme PF01676.18 GBG60236.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DNA_pol_B_palm PF14792.6 GBG60238.1 - 3.2e-26 91.8 0.0 5.7e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 GBG60238.1 - 6.4e-18 64.3 0.0 1.4e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 GBG60238.1 - 3.5e-13 49.7 0.0 4.4e-12 46.2 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.6 GBG60238.1 - 2.3e-11 43.7 0.4 1.1e-10 41.5 0.0 2.5 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_5 PF14520.6 GBG60238.1 - 0.00013 22.5 0.0 0.00058 20.4 0.0 2.0 1 1 1 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 GBG60238.1 - 0.00017 21.8 0.0 0.00047 20.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain BRCT_2 PF16589.5 GBG60238.1 - 0.0023 18.3 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Cdd1 PF11731.8 GBG60238.1 - 0.0092 16.2 0.0 0.67 10.2 0.0 2.6 2 0 0 2 2 2 1 Pathogenicity locus IMS_HHH PF11798.8 GBG60238.1 - 0.014 15.6 0.1 0.42 11.0 0.0 2.9 2 0 0 2 2 2 0 IMS family HHH motif Herpes_U5 PF05999.11 GBG60238.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family CDC45 PF02724.14 GBG60238.1 - 2.9 6.1 7.0 8.4 4.5 7.0 1.8 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.19 GBG60239.1 - 5.5e-05 23.7 22.1 9.6e-05 22.9 22.1 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein BAF1_ABF1 PF04684.13 GBG60239.1 - 0.06 12.4 25.1 0.053 12.6 5.8 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor BUD22 PF09073.10 GBG60239.1 - 0.28 10.5 15.4 1.6 8.0 10.9 2.0 2 0 0 2 2 2 0 BUD22 FAM60A PF15396.6 GBG60239.1 - 8.2 6.4 9.0 2.6 8.0 1.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A NPH3 PF03000.14 GBG60241.1 - 7.3e-05 22.5 0.1 0.0002 21.1 0.0 1.7 2 1 0 2 2 2 1 NPH3 family BTB PF00651.31 GBG60241.1 - 0.002 18.3 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MIP-T3_C PF17749.1 GBG60241.1 - 0.011 15.7 1.3 0.017 15.1 1.3 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4715 PF15835.5 GBG60241.1 - 0.013 15.5 1.6 0.03 14.4 1.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) Fib_alpha PF08702.10 GBG60241.1 - 0.022 14.9 0.6 0.035 14.3 0.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 GBG60241.1 - 0.04 14.0 10.9 0.065 13.3 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Not3 PF04065.15 GBG60241.1 - 0.047 13.1 3.9 0.071 12.5 3.9 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component TSC22 PF01166.18 GBG60241.1 - 0.054 13.8 2.2 0.32 11.3 1.6 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Syntaxin-6_N PF09177.11 GBG60241.1 - 0.062 13.9 2.5 0.13 12.9 2.5 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Shugoshin_N PF07558.11 GBG60241.1 - 0.091 12.6 0.8 0.21 11.5 0.8 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF4618 PF15397.6 GBG60241.1 - 0.11 12.0 4.9 0.18 11.2 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) PspA_IM30 PF04012.12 GBG60241.1 - 0.13 11.8 6.0 0.25 10.9 6.0 1.4 1 1 0 1 1 1 0 PspA/IM30 family YabA PF06156.13 GBG60241.1 - 0.22 12.2 9.4 0.35 11.5 3.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 GBG60241.1 - 0.39 10.8 7.6 0.41 10.7 0.9 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IFT20 PF14931.6 GBG60241.1 - 0.49 10.6 8.3 1.5 9.0 8.3 1.7 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 V_ATPase_I PF01496.19 GBG60241.1 - 0.52 8.2 3.0 0.69 7.8 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.9 GBG60241.1 - 0.56 10.4 8.2 0.91 9.7 8.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF724 PF05266.14 GBG60241.1 - 0.62 9.9 7.5 0.44 10.3 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 GBG60241.1 - 0.78 8.6 8.4 1.1 8.1 8.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tektin PF03148.14 GBG60241.1 - 0.81 8.4 9.1 1.7 7.3 9.1 1.5 1 1 0 1 1 1 0 Tektin family Prefoldin_2 PF01920.20 GBG60241.1 - 0.93 9.5 5.4 0.53 10.3 1.7 2.0 2 0 0 2 2 2 0 Prefoldin subunit Spc24 PF08286.11 GBG60241.1 - 0.96 9.7 4.6 0.29 11.4 1.5 1.6 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 CLZ PF16526.5 GBG60241.1 - 1 9.8 10.3 0.16 12.4 5.0 2.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 GBG60241.1 - 1.1 8.6 5.7 4.2 6.6 5.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) COG2 PF06148.11 GBG60241.1 - 1.3 9.1 4.5 24 5.0 4.5 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.12 GBG60241.1 - 1.3 9.6 5.8 0.85 10.3 2.0 2.2 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 GBG60241.1 - 1.4 8.7 4.4 1.2 9.0 0.8 2.2 1 1 1 2 2 2 0 Septum formation initiator Dzip-like_N PF13815.6 GBG60241.1 - 2.5 8.1 5.1 3.2 7.8 1.4 2.1 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal THOC7 PF05615.13 GBG60241.1 - 2.9 8.2 9.8 6.7 7.0 9.8 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 APG6_N PF17675.1 GBG60241.1 - 8.2 7.0 10.5 15 6.1 10.5 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region NPH3 PF03000.14 GBG60243.1 - 7e-29 101.2 0.0 1.6e-20 73.9 0.0 2.3 2 0 0 2 2 2 2 NPH3 family BTB PF00651.31 GBG60243.1 - 2e-05 24.8 0.0 5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain APG17 PF04108.12 GBG60243.1 - 0.054 12.6 0.6 0.088 11.9 0.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 THOC7 PF05615.13 GBG60243.1 - 0.3 11.3 6.1 0.75 10.1 6.1 1.6 1 0 0 1 1 1 0 Tho complex subunit 7 YabA PF06156.13 GBG60243.1 - 0.64 10.7 7.4 1.5 9.5 2.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA CCDC-167 PF15188.6 GBG60243.1 - 2 8.8 5.5 6.6 7.2 5.4 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF659 PF04937.15 GBG60244.1 - 6.7e-24 84.5 0.0 1.1e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60244.1 - 0.0035 17.1 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG60245.1 - 1.5e-18 67.1 0.0 5.3e-16 58.8 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Beta_helix PF13229.6 GBG60245.1 - 6.4e-10 39.1 21.4 0.00012 22.0 17.9 2.6 1 1 2 3 3 3 3 Right handed beta helix region RVT_1 PF00078.27 GBG60246.1 - 6.2e-09 35.7 0.0 9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG60247.1 - 7.5e-10 38.7 0.0 3.1e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60247.1 - 1.5e-06 28.8 0.0 3.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60247.1 - 0.00042 20.8 0.0 0.00096 19.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Glucan_synthase PF02364.15 GBG60247.1 - 0.091 10.9 0.0 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 1,3-beta-glucan synthase component FAM184 PF15665.5 GBG60248.1 - 0.014 15.2 15.5 0.018 14.8 14.4 1.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B PIN_8 PF18476.1 GBG60248.1 - 0.53 10.1 11.0 0.095 12.5 4.8 2.1 2 0 0 2 2 2 0 PIN like domain YscO PF07321.12 GBG60248.1 - 3.7 7.5 31.7 0.99 9.4 7.0 3.3 3 0 0 3 3 3 0 Type III secretion protein YscO SPOUT_MTase PF02590.17 GBG60248.1 - 5.9 6.9 8.9 1.8 8.5 3.3 2.6 2 1 1 3 3 3 0 Predicted SPOUT methyltransferase DUF2935 PF11155.8 GBG60249.1 - 0.021 15.2 3.1 0.029 14.7 2.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.10 GBG60249.1 - 1.3 9.2 7.5 3.5 7.8 7.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ECH_2 PF16113.5 GBG60249.1 - 2.6 7.4 7.7 3.5 7.0 7.7 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF4055 PF13264.6 GBG60249.1 - 2.9 8.0 8.1 12 6.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) PIN_8 PF18476.1 GBG60249.1 - 7.7 6.3 12.3 3.9 7.3 8.2 1.9 1 1 1 2 2 2 0 PIN like domain NPH3 PF03000.14 GBG60250.1 - 1.6e-29 103.3 0.0 8.5e-22 78.0 0.0 2.8 3 0 0 3 3 3 2 NPH3 family BTB PF00651.31 GBG60250.1 - 4.8e-07 30.0 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain CLZ PF16526.5 GBG60250.1 - 0.00044 20.5 2.3 0.0012 19.1 2.3 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Uso1_p115_C PF04871.13 GBG60250.1 - 0.062 13.7 3.3 0.11 12.8 3.3 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Flagellar_rod PF05149.12 GBG60250.1 - 0.068 12.6 7.0 0.13 11.7 7.0 1.5 1 0 0 1 1 1 0 Paraflagellar rod protein K-box PF01486.17 GBG60250.1 - 0.069 13.3 6.2 5.1 7.3 1.0 3.2 3 0 0 3 3 3 0 K-box region GIT_CC PF16559.5 GBG60250.1 - 0.079 12.8 1.6 0.22 11.4 0.9 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5082 PF16888.5 GBG60250.1 - 0.079 13.2 0.7 0.16 12.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF3342 PF11822.8 GBG60250.1 - 0.094 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Jnk-SapK_ap_N PF09744.9 GBG60250.1 - 0.12 12.6 6.7 0.22 11.7 6.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Syntaxin-6_N PF09177.11 GBG60250.1 - 0.14 12.8 0.7 0.44 11.1 0.7 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal KASH_CCD PF14662.6 GBG60250.1 - 0.19 11.5 7.9 0.32 10.8 7.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TolA_bind_tri PF16331.5 GBG60250.1 - 0.2 11.8 4.8 0.49 10.5 4.8 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Fib_alpha PF08702.10 GBG60250.1 - 0.48 10.6 1.6 0.85 9.8 1.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 GBG60250.1 - 0.78 8.6 7.6 1.6 7.6 7.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 GBG60250.1 - 0.85 10.3 9.4 0.76 10.4 3.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 GBG60250.1 - 0.98 10.4 8.0 2.4 9.1 8.0 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain THOC7 PF05615.13 GBG60250.1 - 1.1 9.6 6.9 2.8 8.2 6.9 1.6 1 0 0 1 1 1 0 Tho complex subunit 7 STAT_alpha PF01017.20 GBG60250.1 - 1.9 8.3 5.3 0.67 9.8 1.1 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain BRE1 PF08647.11 GBG60250.1 - 4.2 7.5 7.0 12 6.1 1.5 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 GBG60250.1 - 8.3 4.8 8.3 13 4.1 8.3 1.2 1 0 0 1 1 1 0 Macoilin family Metallophos PF00149.28 GBG60251.1 - 1.9e-36 126.5 0.1 2.3e-36 126.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GBG60251.1 - 0.21 11.8 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RT_RNaseH_2 PF17919.1 GBG60252.1 - 1.3e-31 108.6 0.0 2.6e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60252.1 - 4.8e-28 98.2 0.3 8.5e-28 97.4 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60252.1 - 8.2e-28 96.8 0.1 1.6e-27 95.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60252.1 - 0.026 15.1 0.0 0.08 13.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG60252.1 - 0.042 14.0 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain DUF1758 PF05585.12 GBG60252.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG60252.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60252.1 - 0.12 13.0 0.0 0.34 11.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease HIT PF01230.23 GBG60253.1 - 7.5e-21 74.7 0.6 1.5e-20 73.8 0.6 1.5 1 0 0 1 1 1 1 HIT domain MMR_HSR1 PF01926.23 GBG60253.1 - 1.1e-16 60.9 0.0 2.7e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG60253.1 - 5.2e-09 35.8 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B KH_2 PF07650.17 GBG60253.1 - 5.6e-09 35.7 0.7 1.2e-08 34.7 0.7 1.4 1 0 0 1 1 1 1 KH domain RsgA_GTPase PF03193.16 GBG60253.1 - 2e-06 27.8 0.1 0.033 14.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GBG60253.1 - 6.8e-06 25.8 0.3 0.016 14.7 0.0 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GBG60253.1 - 0.0015 18.6 0.9 0.22 11.6 0.2 3.0 2 1 1 3 3 3 1 Dynamin family PduV-EutP PF10662.9 GBG60253.1 - 0.0052 16.5 0.0 0.077 12.7 0.0 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 GBG60253.1 - 0.02 15.1 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GBG60253.1 - 0.024 14.3 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Ras family AIG1 PF04548.16 GBG60253.1 - 0.035 13.4 0.1 0.059 12.7 0.1 1.4 1 0 0 1 1 1 0 AIG1 family RT_RNaseH_2 PF17919.1 GBG60256.1 - 4.2e-23 81.3 0.0 9.3e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60256.1 - 2e-22 79.4 0.0 4.6e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG60256.1 - 0.00049 20.4 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60256.1 - 0.0075 16.8 0.0 0.021 15.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG60256.1 - 0.089 12.6 0.6 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG60257.1 - 7.3e-61 202.4 0.1 8.1e-31 106.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60257.1 - 4.8e-57 190.7 0.6 6.7e-28 97.1 0.1 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60257.1 - 3.6e-34 116.7 6.3 2.2e-17 62.9 0.2 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG60257.1 - 1e-32 113.5 0.3 4.4e-28 98.3 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60257.1 - 2.4e-09 37.4 0.0 8.1e-06 26.0 0.0 3.1 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG60257.1 - 0.00054 20.1 1.6 0.034 14.4 0.4 2.9 2 0 0 2 2 2 1 H2C2 zinc finger UbiA PF01040.18 GBG60258.1 - 2e-22 79.7 2.0 2.7e-22 79.3 2.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Hydrophobin_2 PF06766.11 GBG60259.1 - 0.01 15.8 1.4 0.014 15.3 1.4 1.2 1 0 0 1 1 1 0 Fungal hydrophobin CCD48 PF15799.5 GBG60260.1 - 0.00014 20.3 1.4 0.00023 19.7 1.4 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 DivIC PF04977.15 GBG60260.1 - 0.011 15.5 0.8 0.034 13.9 0.8 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF848 PF05852.11 GBG60260.1 - 0.034 14.3 0.4 0.034 14.3 0.4 1.7 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) bZIP_2 PF07716.15 GBG60260.1 - 0.066 13.3 1.3 0.2 11.8 1.3 1.8 1 0 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.18 GBG60260.1 - 0.077 13.2 1.2 0.077 13.2 1.2 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper ABC_tran_CTD PF16326.5 GBG60260.1 - 0.31 11.3 5.7 0.88 9.9 0.5 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain RVT_1 PF00078.27 GBG60261.1 - 3.2e-19 69.3 0.0 3.8e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60261.1 - 1.4e-17 63.5 0.2 5.7e-17 61.6 0.3 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG60261.1 - 1.1e-11 45.0 0.2 3.9e-11 43.2 0.2 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG60261.1 - 0.00036 20.8 9.6 0.2 12.0 0.1 5.1 4 0 0 4 4 4 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG60261.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG60261.1 - 0.0016 18.4 0.1 0.0051 16.8 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG60261.1 - 0.011 16.3 0.0 0.027 15.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease FlxA PF14282.6 GBG60261.1 - 0.029 14.4 0.1 0.029 14.4 0.1 4.1 4 0 0 4 4 3 0 FlxA-like protein gag-asp_proteas PF13975.6 GBG60261.1 - 0.035 14.7 0.0 0.096 13.3 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease ABC_tran_Xtn PF12848.7 GBG60261.1 - 0.28 11.2 7.8 1.5 8.9 7.8 2.3 1 0 0 1 1 1 0 ABC transporter HalX PF08663.10 GBG60261.1 - 0.34 11.3 4.9 29 5.1 0.1 4.8 4 0 0 4 4 4 0 HalX domain Snapin_Pallidin PF14712.6 GBG60261.1 - 2.4 8.6 8.8 0.84 10.1 0.1 4.0 4 0 0 4 4 4 0 Snapin/Pallidin RVT_1 PF00078.27 GBG60262.1 - 2.8e-28 99.0 0.5 6.4e-28 97.8 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60262.1 - 1.6e-11 44.4 1.6 2.9e-11 43.6 0.1 2.2 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG60262.1 - 9e-06 25.5 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60262.1 - 1.2e-05 25.8 0.0 3.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60262.1 - 3.1e-05 24.5 0.0 7.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60262.1 - 0.00091 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease FlxA PF14282.6 GBG60262.1 - 0.032 14.2 0.1 0.032 14.2 0.1 3.8 4 1 1 5 5 5 0 FlxA-like protein Retrotrans_gag PF03732.17 GBG60262.1 - 0.085 13.1 1.3 2.1 8.6 0.3 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein SlyX PF04102.12 GBG60262.1 - 0.37 11.4 10.3 0.59 10.8 0.0 4.7 4 0 0 4 4 4 0 SlyX Gpi1 PF05024.15 GBG60263.1 - 2.2e-48 164.8 1.6 4.3e-48 163.9 1.6 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) RT_RNaseH_2 PF17919.1 GBG60263.1 - 9.2e-29 99.4 0.0 1.3e-26 92.5 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60263.1 - 2.4e-25 89.4 0.0 3.4e-20 72.5 0.0 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60263.1 - 1.3e-22 80.1 0.1 3.6e-22 78.6 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60263.1 - 1.6e-09 37.9 0.0 5e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG60263.1 - 5.8e-07 30.1 0.0 2e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60263.1 - 2.5e-06 27.9 0.0 1.3e-05 25.7 0.0 2.3 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG60263.1 - 3.2e-05 24.2 1.0 3.2e-05 24.2 1.0 2.3 2 0 0 2 2 1 1 Myb/SANT-like DNA-binding domain RVP_2 PF08284.11 GBG60263.1 - 5.6e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60263.1 - 0.00084 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease SPACA9 PF15120.6 GBG60263.1 - 0.25 11.1 1.3 0.82 9.4 1.3 1.9 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 CorA PF01544.18 GBG60263.1 - 0.33 10.2 2.9 1.3 8.3 2.9 2.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AKNA PF12443.8 GBG60263.1 - 2.4 8.8 6.6 0.53 11.0 0.2 3.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor Sec2p PF06428.11 GBG60263.1 - 6.5 6.8 13.1 3 7.9 0.1 3.4 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p NPV_P10 PF05531.12 GBG60263.1 - 9 6.8 8.9 3.2 8.3 0.4 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein RT_RNaseH_2 PF17919.1 GBG60264.1 - 1.9e-22 79.2 0.0 3.7e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60264.1 - 3.7e-21 75.4 0.0 7.4e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60264.1 - 4.8e-19 68.2 0.6 1.1e-18 67.0 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG60264.1 - 2.1e-13 50.3 0.0 3.8e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG60264.1 - 0.007 16.3 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG60264.1 - 0.018 15.3 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger HSR PF03172.13 GBG60264.1 - 0.082 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 HSR domain Asp_protease_2 PF13650.6 GBG60265.1 - 0.00012 22.6 0.0 0.00034 21.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60265.1 - 0.00026 20.8 0.0 0.00065 19.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG60265.1 - 0.0006 20.0 0.2 0.0006 20.0 0.2 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG60265.1 - 0.0014 19.2 0.0 0.0044 17.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease AIP3 PF03915.13 GBG60265.1 - 0.0082 15.3 1.3 0.013 14.6 1.3 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 DUF4187 PF13821.6 GBG60265.1 - 0.015 15.1 0.6 0.033 14.0 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Asp_protease PF09668.10 GBG60265.1 - 0.085 12.7 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Aspartyl protease DUF4407 PF14362.6 GBG60265.1 - 0.84 8.9 12.6 2.4 7.4 12.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Integrase_H2C2 PF17921.1 GBG60266.1 - 4.5e-16 58.7 0.0 1.1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG60266.1 - 3.8e-12 46.2 0.0 6.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60266.1 - 1.2e-10 41.6 0.0 3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG60266.1 - 2.7e-05 24.3 0.0 5.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG60266.1 - 0.017 15.8 0.0 0.036 14.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG60268.1 - 2.9e-16 59.7 0.2 2.8e-15 56.5 0.1 2.7 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60268.1 - 5e-14 52.1 0.2 3.8e-13 49.3 0.0 2.6 3 1 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG60268.1 - 0.0061 16.8 0.0 0.023 14.9 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein Acid_PPase PF12689.7 GBG60268.1 - 0.18 11.6 0.7 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Acid Phosphatase Cwf_Cwc_15 PF04889.12 GBG60270.1 - 0.0041 16.9 25.5 0.15 11.8 16.1 2.2 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein TAF1D PF15333.6 GBG60270.1 - 0.16 11.6 18.1 0.023 14.5 3.6 2.4 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D DUF3819 PF12842.7 GBG60270.1 - 0.23 11.4 5.1 0.38 10.7 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) CENP-X PF09415.10 GBG60270.1 - 0.64 10.4 8.5 0.53 10.6 1.5 3.2 3 0 0 3 3 3 0 CENP-S associating Centromere protein X SR-25 PF10500.9 GBG60270.1 - 1.2 8.7 29.2 0.034 13.7 4.3 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein CENP-I PF07778.11 GBG60270.1 - 9.1 4.9 9.2 0.4 9.3 0.7 2.2 2 0 0 2 2 2 0 Mis6 Toxin_17 PF08086.11 GBG60271.1 - 0.11 12.8 10.2 0.21 11.9 10.2 1.6 1 1 0 1 1 1 0 Ergtoxin family RT_RNaseH_2 PF17919.1 GBG60272.1 - 1.4e-32 111.7 0.0 3e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60272.1 - 1.5e-29 102.4 0.1 3.2e-29 101.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60272.1 - 1.3e-21 77.1 0.0 2.3e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60272.1 - 2.5e-15 56.3 0.0 5.8e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60272.1 - 2.4e-09 37.4 0.1 7.2e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain CNOT1_HEAT_N PF16419.5 GBG60272.1 - 0.068 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat RVT_1 PF00078.27 GBG60273.1 - 7.7e-37 127.0 0.0 1.4e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60273.1 - 1.6e-31 108.2 0.0 4.4e-31 106.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60273.1 - 8.8e-31 106.3 0.0 2.3e-30 105.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG60273.1 - 2.1e-06 27.5 0.0 4.9e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60273.1 - 8.2e-06 26.4 0.0 2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60273.1 - 0.0003 21.3 0.1 0.0012 19.4 0.1 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG60273.1 - 0.0024 17.6 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) PB1 PF00564.24 GBG60274.1 - 0.21 11.5 0.6 31 4.6 0.3 2.7 2 0 0 2 2 2 0 PB1 domain RVT_1 PF00078.27 GBG60275.1 - 3.4e-31 108.5 0.1 5e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60275.1 - 4.6e-18 65.1 0.0 1.1e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60275.1 - 2.1e-09 37.6 0.0 3.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG60275.1 - 0.11 12.6 3.5 0.24 11.6 3.5 1.6 1 0 0 1 1 1 0 Zinc knuckle APG17 PF04108.12 GBG60275.1 - 0.12 11.4 0.0 1.7 7.7 0.0 1.9 1 1 1 2 2 2 0 Autophagy protein Apg17 zf-CCHC_3 PF13917.6 GBG60275.1 - 0.21 11.6 0.2 0.21 11.6 0.2 1.9 2 0 0 2 2 2 0 Zinc knuckle KNOX2 PF03791.13 GBG60276.1 - 0.17 11.4 2.2 1.3 8.5 0.1 4.0 2 0 0 2 2 2 0 KNOX2 domain gag-asp_proteas PF13975.6 GBG60277.1 - 0.00059 20.3 0.0 0.0016 18.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60277.1 - 0.0013 18.6 0.2 0.0065 16.3 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG60277.1 - 0.0021 18.7 0.0 0.0048 17.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG60277.1 - 0.0092 15.8 1.0 0.015 15.1 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 GBG60277.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG60277.1 - 0.12 12.7 0.5 0.26 11.6 0.5 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_6 PF15288.6 GBG60277.1 - 0.17 11.8 0.3 0.41 10.5 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG60277.1 - 0.31 11.2 1.5 0.51 10.5 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG60278.1 - 7.6e-26 91.0 0.1 1.2e-25 90.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60278.1 - 1e-14 54.4 0.3 2.7e-14 53.0 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG60278.1 - 2.9e-08 33.9 0.1 6.8e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60278.1 - 9.6e-08 32.5 0.0 2.7e-07 31.1 0.0 1.8 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60278.1 - 1.3e-07 32.1 0.0 3.2e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60278.1 - 6.9e-07 29.1 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG60278.1 - 5.2e-06 26.4 0.1 0.021 14.8 0.0 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60278.1 - 1.8e-05 24.9 0.0 5.1e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG60278.1 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG60278.1 - 0.00019 21.6 0.2 0.001 19.3 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG60278.1 - 0.00039 20.3 0.2 0.0041 17.0 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG60279.1 - 3e-15 56.4 0.0 3.8e-14 52.9 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60279.1 - 7.1e-13 48.5 0.0 2.2e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG60279.1 - 1.4e-12 47.5 0.0 3.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60279.1 - 8.9e-05 22.1 0.0 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG60279.1 - 0.016 15.5 0.2 0.12 12.7 0.1 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein Choline_kin_N PF04428.14 GBG60279.1 - 0.16 11.7 0.0 0.48 10.1 0.0 1.8 1 0 0 1 1 1 0 Choline kinase N terminus RVT_1 PF00078.27 GBG60280.1 - 2.5e-36 125.3 0.0 3.6e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG60280.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG60282.1 - 0.00077 19.7 0.3 0.004 17.4 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein PapC_C PF13953.6 GBG60282.1 - 0.0023 17.7 18.7 2.1 8.2 0.4 6.1 2 2 5 7 7 7 6 PapC C-terminal domain Integrase_H2C2 PF17921.1 GBG60283.1 - 7.5e-13 48.4 0.0 1.8e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG60283.1 - 4.6e-05 23.0 0.0 9.4e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60284.1 - 1.6e-33 114.7 0.0 3.8e-33 113.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60284.1 - 5e-29 100.7 0.1 1.2e-28 99.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60284.1 - 9.5e-18 64.1 0.1 2.1e-17 62.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60284.1 - 2.9e-15 56.5 0.0 7.7e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG60284.1 - 1.9e-13 50.4 1.3 1.2e-11 44.6 0.2 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG60284.1 - 0.00032 20.6 2.6 0.00081 19.4 2.6 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF1564 PF07600.11 GBG60284.1 - 0.013 15.2 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG60284.1 - 0.032 14.4 0.2 0.21 11.8 0.0 2.6 3 0 0 3 3 2 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG60284.1 - 0.071 13.4 0.7 0.23 11.7 0.0 2.3 2 0 0 2 2 1 0 Retrotransposon gag protein CotJB PF12652.7 GBG60284.1 - 0.15 12.3 1.0 35 4.7 0.0 3.5 3 0 0 3 3 3 0 CotJB protein DIL PF01843.19 GBG60284.1 - 0.6 10.4 2.0 3.1 8.1 0.0 3.1 4 0 0 4 4 4 0 DIL domain Acetate_kinase PF00871.17 GBG60284.1 - 0.65 8.6 2.4 1.7 7.3 2.4 1.6 1 0 0 1 1 1 0 Acetokinase family DDHD PF02862.17 GBG60284.1 - 1.2 9.2 5.5 5.2 7.2 5.5 2.0 1 1 0 1 1 1 0 DDHD domain XRN_M PF17846.1 GBG60284.1 - 2.2 7.1 6.5 3.9 6.3 6.5 1.3 1 0 0 1 1 1 0 Xrn1 helical domain RR_TM4-6 PF06459.12 GBG60284.1 - 7.2 6.4 12.2 18 5.1 12.2 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GBG60284.1 - 8.8 4.5 12.6 15 3.8 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG60286.1 - 1.2e-22 79.8 0.0 2.7e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60286.1 - 1.3e-20 73.6 0.0 3.8e-20 72.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60286.1 - 1.6e-07 31.5 0.0 3.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG60286.1 - 0.036 14.6 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG60286.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60286.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG60286.1 - 0.051 14.2 0.0 0.17 12.5 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.6 GBG60286.1 - 0.054 13.3 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG60287.1 - 2.4e-51 171.9 0.0 1.9e-24 85.6 0.0 3.4 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60287.1 - 9.4e-47 157.6 0.0 2.3e-21 76.0 0.0 4.3 5 0 0 5 5 4 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60287.1 - 3.3e-13 49.5 0.2 1.1e-12 47.9 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG60287.1 - 5.6e-09 36.2 3.3 0.18 12.1 0.0 5.1 4 1 1 5 5 5 3 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG60287.1 - 0.0003 21.3 0.0 1.1 9.8 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG60287.1 - 0.00095 19.4 0.2 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease rve PF00665.26 GBG60287.1 - 0.0011 19.1 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain TMF_TATA_bd PF12325.8 GBG60287.1 - 0.0014 18.9 4.7 0.016 15.4 4.7 3.0 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding RVT_1 PF00078.27 GBG60287.1 - 0.011 15.2 0.0 0.03 13.8 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Choline_kin_N PF04428.14 GBG60287.1 - 0.045 13.4 0.0 21 4.9 0.0 3.0 3 0 0 3 3 3 0 Choline kinase N terminus YabA PF06156.13 GBG60287.1 - 0.069 13.8 3.0 0.56 10.9 3.0 2.7 1 0 0 1 1 1 0 Initiation control protein YabA Bap31_Bap29_C PF18035.1 GBG60287.1 - 0.086 12.9 3.0 0.32 11.0 3.0 2.0 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Sec8_exocyst PF04048.14 GBG60287.1 - 0.095 12.6 1.0 0.31 10.9 1.0 1.9 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Strep_SA_rep PF06696.11 GBG60287.1 - 0.13 12.3 4.3 8.2 6.6 0.2 2.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF1664 PF07889.12 GBG60287.1 - 0.18 11.8 5.8 0.36 10.9 2.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 GBG60287.1 - 0.24 9.3 3.0 0.42 8.5 3.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4763 PF15960.5 GBG60287.1 - 0.5 9.6 0.0 0.5 9.6 0.0 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4763) ImpA_N PF06812.12 GBG60287.1 - 0.54 10.4 3.1 21 5.3 3.6 3.0 2 1 1 3 3 3 0 ImpA, N-terminal, type VI secretion system GAS PF13851.6 GBG60287.1 - 2.3 7.5 9.6 1.5 8.1 5.6 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 GBG60287.1 - 6.5 6.6 7.8 2.2 8.1 2.8 3.0 2 0 0 2 2 1 0 Septum formation initiator Retrotrans_gag PF03732.17 GBG60288.1 - 0.017 15.4 0.0 0.059 13.7 0.0 1.9 1 1 1 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 GBG60288.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG60289.1 - 2.8e-26 92.4 0.0 5.5e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG60289.1 - 0.38 11.0 0.1 0.38 11.0 0.1 4.7 4 0 0 4 4 4 0 Retrotransposon gag protein Rotamase_2 PF13145.6 GBG60289.1 - 7.5 7.4 11.7 1 10.2 6.1 2.5 3 0 0 3 3 3 0 PPIC-type PPIASE domain RVT_1 PF00078.27 GBG60290.1 - 5.3e-21 75.2 0.1 1.1e-20 74.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60290.1 - 2e-17 63.0 0.1 5.5e-17 61.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG60290.1 - 7.6e-11 42.2 0.2 1.6e-10 41.2 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60290.1 - 2.5e-10 40.6 0.0 7.6e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG60290.1 - 0.0065 16.5 0.0 0.019 15.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Nif11 PF07862.11 GBG60290.1 - 0.13 12.5 0.1 0.78 10.1 0.0 2.3 3 0 0 3 3 3 0 Nif11 domain gag-asp_proteas PF13975.6 GBG60293.1 - 0.0042 17.6 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60293.1 - 0.012 16.3 0.0 0.027 15.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG60293.1 - 0.1 12.5 0.6 0.16 11.9 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG60294.1 - 6.9e-06 26.5 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60294.1 - 0.00058 20.5 0.0 0.0017 19.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60294.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG60294.1 - 0.022 14.6 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF1904 PF08921.11 GBG60294.1 - 0.1 12.9 0.1 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) Asp_protease PF09668.10 GBG60294.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF4674 PF15719.5 GBG60294.1 - 0.21 11.6 5.3 0.39 10.7 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) RT_RNaseH PF17917.1 GBG60295.1 - 3.2e-32 110.9 0.1 5.9e-31 106.9 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60295.1 - 2.4e-31 107.7 0.0 4.3e-30 103.7 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60295.1 - 4e-19 68.5 0.6 1e-18 67.2 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60295.1 - 1.5e-15 57.4 0.1 6.8e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG60295.1 - 9.7e-12 44.9 0.0 2.1e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG60295.1 - 0.0011 19.2 0.1 0.0026 17.9 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger CHD5 PF04420.14 GBG60295.1 - 0.058 13.3 1.8 0.16 11.8 1.8 1.7 1 0 0 1 1 1 0 CHD5-like protein Casc1_N PF15927.5 GBG60295.1 - 3.3 7.3 35.5 0.22 11.2 14.5 2.6 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Dimer_Tnp_hAT PF05699.14 GBG60296.1 - 0.002 17.9 0.1 0.0036 17.1 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCHC PF00098.23 GBG60298.1 - 5.6e-06 26.2 1.5 1.3e-05 25.1 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG60298.1 - 0.039 13.7 2.1 0.089 12.5 2.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF5615 PF18480.1 GBG60298.1 - 0.043 13.6 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) Terminase_2 PF03592.16 GBG60299.1 - 0.024 15.1 0.1 0.059 13.8 0.1 1.6 1 0 0 1 1 1 0 Terminase small subunit Methyltransf_9 PF08003.11 GBG60300.1 - 0.054 12.4 0.4 0.08 11.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CDC45 PF02724.14 GBG60301.1 - 7 4.8 19.8 11 4.2 19.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Retrotrans_gag PF03732.17 GBG60302.1 - 0.014 15.7 0.0 0.014 15.7 0.0 3.7 4 2 1 5 5 5 0 Retrotransposon gag protein CLZ PF16526.5 GBG60302.1 - 0.047 14.0 0.9 0.047 14.0 0.9 3.5 3 2 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 GBG60302.1 - 0.057 13.5 0.6 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 GBG60302.1 - 0.064 13.5 0.2 0.064 13.5 0.2 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 GBG60302.1 - 0.38 10.1 11.8 0.46 9.8 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RNR_Alpha PF17975.1 GBG60302.1 - 0.64 10.5 2.7 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain PRKG1_interact PF15898.5 GBG60302.1 - 0.74 10.8 10.1 0.15 12.9 0.7 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain RT_RNaseH_2 PF17919.1 GBG60304.1 - 1.1e-26 92.8 0.0 3.3e-26 91.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60304.1 - 3.6e-25 88.3 0.0 7.4e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60304.1 - 2.9e-18 65.7 0.3 6.7e-18 64.6 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG60304.1 - 5.7e-08 32.5 0.1 0.0018 17.9 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60304.1 - 1.9e-06 28.0 0.0 4.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG60304.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG60305.1 - 2.1e-14 53.4 0.0 9.3e-14 51.3 0.0 2.2 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG60306.1 - 4e-32 110.2 0.0 1.2e-31 108.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60306.1 - 2.1e-28 98.7 0.1 4.9e-28 97.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60306.1 - 2.9e-12 46.6 0.1 5.3e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG60306.1 - 2.1e-11 43.5 0.4 2.6e-10 40.0 0.0 2.6 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 GBG60306.1 - 3.8e-06 27.4 0.0 8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60306.1 - 0.00012 22.6 0.0 0.00029 21.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG60306.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.26 GBG60306.1 - 0.018 15.2 0.1 0.045 13.9 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain Asp_protease PF09668.10 GBG60306.1 - 0.095 12.5 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG60306.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) HepII_C PF18675.1 GBG60306.1 - 0.12 12.5 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Heparinase II C-terminal domain gag-asp_proteas PF13975.6 GBG60308.1 - 4.2e-08 33.6 0.1 4.1e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60308.1 - 2.7e-06 27.9 0.0 7.6e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60308.1 - 0.00054 19.8 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ATG16 PF08614.11 GBG60308.1 - 0.001 19.3 21.1 0.001 19.3 21.1 3.1 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 GBG60308.1 - 0.0055 17.1 5.7 0.0055 17.1 5.7 4.4 5 0 0 5 5 5 2 Flagella accessory protein C (FlaC) RVP PF00077.20 GBG60308.1 - 0.075 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease CK2S PF15011.6 GBG60308.1 - 0.2 11.6 6.2 0.52 10.2 6.2 1.7 1 0 0 1 1 1 0 Casein Kinase 2 substrate Prominin PF05478.11 GBG60308.1 - 0.45 8.4 6.4 0.74 7.7 6.4 1.2 1 0 0 1 1 1 0 Prominin VPS11_C PF12451.8 GBG60308.1 - 1.2 9.4 4.3 7.4 6.9 1.3 2.9 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Spc7 PF08317.11 GBG60308.1 - 5.7 5.7 26.8 0.51 9.2 20.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF659 PF04937.15 GBG60309.1 - 2.8e-18 66.2 0.0 5.1e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVP PF00077.20 GBG60310.1 - 0.00011 22.5 0.0 0.0003 21.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60310.1 - 0.0003 21.3 0.0 0.00068 20.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60310.1 - 0.00099 19.7 0.0 0.0023 18.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG60310.1 - 0.032 14.5 0.2 0.27 11.6 0.0 2.5 2 1 1 3 3 3 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG60310.1 - 0.14 11.9 0.2 0.42 10.4 0.1 1.8 2 0 0 2 2 2 0 Aspartyl protease DUF659 PF04937.15 GBG60311.1 - 4.4e-19 68.8 0.0 7.4e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG60311.1 - 2.3e-14 53.2 0.1 5.5e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60311.1 - 2.3e-12 47.1 0.0 1.4e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG60311.1 - 0.0004 20.6 0.0 0.0024 18.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60311.1 - 0.011 15.7 0.1 0.031 14.3 0.1 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG60311.1 - 0.012 15.9 0.0 0.054 13.8 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG60311.1 - 0.06 13.6 0.3 0.15 12.3 0.3 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG60312.1 - 2.1e-47 159.7 1.7 6.6e-29 100.3 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60312.1 - 5.1e-44 148.4 0.3 2.8e-32 110.7 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60312.1 - 1.8e-28 99.1 0.8 6.1e-14 52.2 0.1 3.3 3 0 0 3 3 3 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG60312.1 - 7.2e-18 64.5 0.0 1.5e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Mcp5_PH PF12814.7 GBG60312.1 - 0.032 14.4 4.5 2.5 8.2 0.4 2.5 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology zf-H2C2 PF09337.10 GBG60312.1 - 0.096 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Ribosomal_L25p PF01386.19 GBG60313.1 - 6.5e-06 26.6 0.0 1.2e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L25p family DUF3959 PF13105.6 GBG60313.1 - 3.5 7.1 6.4 7.1 6.1 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Hyccin PF09790.9 GBG60314.1 - 1.5e-45 155.7 0.0 2.2e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Hyccin RVT_1 PF00078.27 GBG60315.1 - 6.4e-30 104.3 0.0 1.1e-29 103.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60315.1 - 7.3e-18 64.9 0.0 1.5e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG60315.1 - 0.01 15.7 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Rdx PF10262.9 GBG60315.1 - 0.048 13.8 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Rdx family rve PF00665.26 GBG60316.1 - 7.8e-07 29.3 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG60317.1 - 1.4e-28 99.9 0.1 5.3e-28 98.0 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG60317.1 - 0.00038 20.7 5.8 0.00057 20.1 0.1 4.1 4 1 0 4 4 4 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG60317.1 - 0.0058 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease HIP1_clath_bdg PF16515.5 GBG60317.1 - 0.021 15.4 2.8 0.021 15.4 2.8 3.1 4 0 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SR-25 PF10500.9 GBG60318.1 - 0.0061 16.2 23.3 0.0081 15.8 23.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Med19 PF10278.9 GBG60318.1 - 0.048 13.6 27.4 0.057 13.3 27.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Vfa1 PF08432.10 GBG60318.1 - 0.5 10.7 20.1 0.63 10.3 20.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hydin_ADK PF17213.3 GBG60318.1 - 0.53 10.5 6.7 0.6 10.4 6.7 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF3807 PF12720.7 GBG60318.1 - 0.64 10.3 20.3 0.8 9.9 20.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) XRN_M PF17846.1 GBG60318.1 - 1.4 7.8 11.5 1.5 7.7 11.5 1.0 1 0 0 1 1 1 0 Xrn1 helical domain RR_TM4-6 PF06459.12 GBG60318.1 - 1.9 8.3 24.5 2.2 8.1 24.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 GBG60318.1 - 2.1 8.5 13.9 2.5 8.3 13.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.17 GBG60318.1 - 2.2 8.4 6.5 2.6 8.2 6.5 1.2 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 GBG60318.1 - 2.5 7.8 9.4 2.7 7.7 9.4 1.1 1 0 0 1 1 1 0 AAA domain SRP-alpha_N PF04086.13 GBG60318.1 - 3 7.7 24.3 3.8 7.4 24.3 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Spore_coat_CotO PF14153.6 GBG60318.1 - 3.1 7.7 16.7 3.7 7.4 16.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Neur_chan_memb PF02932.16 GBG60318.1 - 5.5 7.0 7.2 5.8 6.9 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 GBG60318.1 - 6.1 5.7 11.7 6.4 5.7 11.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NARP1 PF12569.8 GBG60318.1 - 6.2 5.6 21.5 6.9 5.5 21.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CCDC106 PF15794.5 GBG60318.1 - 7 6.3 20.2 9 5.9 20.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 eIF-3_zeta PF05091.12 GBG60318.1 - 9.5 5.1 13.3 10 5.0 13.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RT_RNaseH_2 PF17919.1 GBG60321.1 - 5.7e-23 80.9 0.0 1.3e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60321.1 - 2.3e-22 79.3 0.0 5.3e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_4 PF14392.6 GBG60321.1 - 0.024 14.3 0.7 0.059 13.1 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG60321.1 - 0.12 12.7 0.1 0.37 11.1 0.1 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein UPF0561 PF10573.9 GBG60321.1 - 9 6.4 6.9 0.52 10.5 0.8 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 gag-asp_proteas PF13975.6 GBG60322.1 - 2.9e-06 27.7 0.1 1.5e-05 25.5 0.1 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60322.1 - 6.6e-06 26.7 0.0 1.8e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG60322.1 - 0.015 15.6 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60322.1 - 0.024 14.4 0.2 0.048 13.5 0.2 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_4 PF14392.6 GBG60322.1 - 0.79 9.5 5.3 1.7 8.4 5.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Collagen PF01391.18 GBG60324.1 - 0.078 12.7 4.9 1.2 9.0 4.9 2.1 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) SDA1 PF05285.12 GBG60324.1 - 2.6 7.4 15.3 3.1 7.1 15.3 1.4 1 0 0 1 1 1 0 SDA1 Myb_DNA-bind_4 PF13837.6 GBG60325.1 - 2e-06 28.1 0.7 4.7e-06 26.9 0.7 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG60325.1 - 0.005 16.9 1.6 0.0071 16.4 0.5 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain OTCace_N PF02729.21 GBG60326.1 - 5.2e-44 149.8 0.0 9.2e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 GBG60326.1 - 1.2e-32 113.1 0.0 1.9e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain EIF_2_alpha PF07541.12 GBG60328.1 - 3e-38 130.5 0.1 7e-38 129.3 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 GBG60328.1 - 2.6e-16 59.7 0.5 2.6e-16 59.7 0.5 2.3 2 0 0 2 2 2 1 S1 RNA binding domain GMC_oxred_N PF00732.19 GBG60328.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.6 1 1 1 2 2 2 0 GMC oxidoreductase EXOSC1 PF10447.9 GBG60328.1 - 0.24 12.0 3.0 0.24 12.0 0.5 2.3 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 rve PF00665.26 GBG60330.1 - 6.3e-15 55.4 0.1 1.7e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG60330.1 - 0.0033 17.7 1.4 0.032 14.5 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein PEARLI-4 PF05278.12 GBG60330.1 - 2.2 7.8 8.4 0.3 10.7 4.3 1.6 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF3729 PF12526.8 GBG60330.1 - 2.2 9.9 8.3 8.8 7.9 8.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) DUF659 PF04937.15 GBG60331.1 - 1.2e-12 48.0 0.6 1.9e-12 47.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG60333.1 - 2.5e-26 92.6 0.1 4e-26 91.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG60334.1 - 4.5e-29 101.6 0.0 7.1e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60334.1 - 8.1e-20 70.7 0.0 1.9e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60334.1 - 2.3e-08 34.3 0.0 1.6e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase PEX-2N PF09263.10 GBG60334.1 - 0.0075 16.6 1.5 0.46 10.8 0.5 2.5 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal Retrotrans_gag PF03732.17 GBG60334.1 - 0.067 13.5 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG60335.1 - 1.1e-28 99.2 0.0 3.7e-28 97.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60335.1 - 3e-28 98.2 1.4 5.1e-28 97.4 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60335.1 - 2.4e-13 50.1 0.0 4.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60335.1 - 7.4e-06 26.2 0.1 2.8e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG60335.1 - 0.077 12.9 0.1 0.46 10.4 0.0 2.4 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Phage_GPO PF05929.11 GBG60335.1 - 9.4 5.8 20.0 0.33 10.5 0.0 2.6 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG60338.1 - 2.3e-26 91.7 0.0 3.9e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60338.1 - 1.6e-23 82.9 0.1 3.3e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60338.1 - 7.5e-19 67.6 0.1 1.8e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60338.1 - 1.6e-15 57.3 0.1 6.2e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG60338.1 - 0.001 19.2 1.4 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 H2C2 zinc finger Mcp5_PH PF12814.7 GBG60338.1 - 0.065 13.4 0.1 0.96 9.6 0.1 2.3 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Cas_DxTHG PF09455.10 GBG60338.1 - 0.076 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family RVT_1 PF00078.27 GBG60339.1 - 5.3e-28 98.1 0.4 9e-28 97.3 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60339.1 - 5.2e-12 45.7 0.0 1.2e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60339.1 - 4.4e-10 39.8 0.4 3e-09 37.1 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG60339.1 - 2e-06 27.7 0.0 4.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG60339.1 - 8.4e-06 25.6 0.0 2.3e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60339.1 - 3.4e-05 24.3 0.0 6.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60339.1 - 4.3e-05 24.1 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60339.1 - 0.00068 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG60339.1 - 0.22 10.6 0.0 0.85 8.7 0.0 1.7 1 1 0 1 1 1 0 Autophagy protein Apg17 Lactamase_B_2 PF12706.7 GBG60340.1 - 0.0063 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Integrase_H2C2 PF17921.1 GBG60341.1 - 1.9e-19 69.5 0.9 4.9e-19 68.2 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG60341.1 - 2.7e-15 56.2 0.0 7e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60341.1 - 3.8e-13 49.6 0.0 1.5e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60341.1 - 4.9e-09 36.0 0.0 8.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG60341.1 - 0.061 13.5 0.2 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF4075 PF13294.6 GBG60343.1 - 0.02 15.0 1.0 0.048 13.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4075) DUF1664 PF07889.12 GBG60343.1 - 0.079 13.0 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SepF PF04472.12 GBG60343.1 - 0.15 12.3 0.2 0.65 10.3 0.0 2.1 2 0 0 2 2 2 0 Cell division protein SepF RT_RNaseH_2 PF17919.1 GBG60344.1 - 6.2e-25 87.1 0.0 1.5e-24 86.0 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60344.1 - 2.4e-19 69.6 0.0 6.1e-19 68.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60344.1 - 0.008 15.7 0.0 0.018 14.6 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60345.1 - 7.1e-15 55.3 0.0 4.7e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG60345.1 - 0.00097 18.9 0.0 0.0041 16.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain MRP-63 PF14978.6 GBG60345.1 - 0.25 12.0 1.5 1.2 9.8 0.1 2.6 3 0 0 3 3 3 0 Mitochondrial ribosome protein 63 K1377 PF15352.6 GBG60346.1 - 4.1 5.5 6.0 5.9 5.0 6.0 1.1 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy Retrotrans_gag PF03732.17 GBG60347.1 - 0.074 13.3 0.0 0.5 10.7 0.0 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG60348.1 - 1.7e-17 63.3 0.0 6e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60348.1 - 2e-07 31.2 0.0 7.1e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG60348.1 - 2.7e-07 30.4 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60348.1 - 0.0011 19.5 0.1 0.0054 17.3 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60348.1 - 0.0031 18.0 0.0 0.018 15.6 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG60348.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF4392 PF14336.6 GBG60348.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) GATase_4 PF13230.6 GBG60348.1 - 0.11 11.4 0.0 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 Glutamine amidotransferases class-II RVT_1 PF00078.27 GBG60349.1 - 3.6e-28 98.6 0.3 8e-28 97.5 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG60349.1 - 9.7e-05 22.6 0.1 0.0026 18.0 0.0 2.8 2 1 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG60350.1 - 2e-14 53.8 0.0 7.7e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60350.1 - 2.7e-12 46.6 0.0 6.7e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60350.1 - 0.00011 22.7 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG60350.1 - 0.0013 19.0 0.1 0.0039 17.5 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60350.1 - 0.0018 18.9 0.0 0.0042 17.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60350.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG60351.1 - 4.2e-24 84.5 0.0 7.7e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60351.1 - 3.7e-22 78.6 0.0 6.8e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60351.1 - 4.9e-12 46.1 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG60351.1 - 0.0062 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain ACT_3 PF10000.9 GBG60351.1 - 0.11 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 ACT domain Retrotrans_gag PF03732.17 GBG60352.1 - 0.0064 16.7 1.2 0.019 15.2 0.1 2.2 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG60353.1 - 9.2e-12 44.9 0.0 5.3e-11 42.4 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60353.1 - 2.3e-07 31.3 0.0 5.7e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG60353.1 - 1.5e-06 27.9 0.6 0.003 17.1 0.1 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG60353.1 - 2e-06 28.4 0.0 4.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60353.1 - 0.00049 19.9 0.0 0.00094 19.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG60353.1 - 0.0028 17.9 0.0 0.0077 16.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG60353.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Cytochrom_B562 PF07361.11 GBG60353.1 - 0.079 13.6 0.4 0.16 12.6 0.4 1.4 1 0 0 1 1 1 0 Cytochrome b562 RT_RNaseH_2 PF17919.1 GBG60354.1 - 2.5e-22 78.8 0.0 5.2e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60354.1 - 8.6e-19 67.8 0.0 3.5e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60354.1 - 9.9e-13 48.3 0.0 2.2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG60357.1 - 0.0028 17.7 2.1 0.0028 17.7 2.1 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG60357.1 - 0.016 15.1 3.2 0.016 15.1 3.2 2.4 3 0 0 3 3 3 0 Zinc knuckle DUF262 PF03235.14 GBG60357.1 - 0.54 10.4 2.8 1 9.5 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF262 ESM4 PF15952.5 GBG60357.1 - 3.3 8.1 7.5 5 7.5 6.4 1.9 2 0 0 2 2 2 0 Enhancer of split M4 family DAG_kinase_N PF14513.6 GBG60357.1 - 4.3 7.5 5.4 17 5.6 0.1 2.5 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus RVT_1 PF00078.27 GBG60360.1 - 2e-28 99.5 0.1 4.4e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60360.1 - 1.2e-22 79.8 0.0 4.7e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60360.1 - 2.3e-21 76.0 0.0 8e-21 74.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG60360.1 - 6.4e-06 26.7 0.0 6.8e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG60360.1 - 2e-05 24.4 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG60360.1 - 0.00012 22.2 5.1 0.023 15.0 0.0 4.1 4 0 0 4 4 4 2 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG60360.1 - 0.00045 20.7 0.0 0.0013 19.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60360.1 - 0.0034 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CLZ PF16526.5 GBG60360.1 - 0.34 11.3 6.6 0.23 11.8 0.8 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Use1 PF09753.9 GBG60360.1 - 2.6 7.7 12.3 8.6 6.0 10.6 2.3 2 0 0 2 2 2 0 Membrane fusion protein Use1 RVT_1 PF00078.27 GBG60361.1 - 1.9e-28 99.5 0.1 3e-28 98.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG60361.1 - 5.1e-08 33.5 0.0 1.3e-07 32.1 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG60361.1 - 5.9e-07 29.3 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60361.1 - 2.1e-06 28.2 0.0 4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60361.1 - 0.00049 19.9 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease F-box-like PF12937.7 GBG60362.1 - 2.2e-11 43.5 0.1 5.7e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG60362.1 - 7.2e-05 22.6 0.1 0.00018 21.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain DUF1729 PF08354.10 GBG60364.1 - 0.078 11.9 2.0 0.092 11.6 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) DeoRC PF00455.22 GBG60364.1 - 0.086 12.8 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 DeoR C terminal sensor domain Peptidase_C48 PF02902.19 GBG60365.1 - 2.4e-10 40.6 0.1 6.9e-10 39.1 0.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4637 PF15470.6 GBG60365.1 - 0.34 10.6 13.3 0.7 9.6 13.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nop14 PF04147.12 GBG60365.1 - 1.1 7.4 31.7 1.5 7.0 31.7 1.1 1 0 0 1 1 1 0 Nop14-like family Prothymosin PF03247.14 GBG60365.1 - 1.7 9.1 37.0 3.2 8.3 37.0 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family RNA_pol_Rpc4 PF05132.14 GBG60365.1 - 3.5 8.0 6.3 3.4 8.1 3.9 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 MscS_TM PF12794.7 GBG60365.1 - 5.4 5.8 7.5 24 3.6 4.8 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Vfa1 PF08432.10 GBG60365.1 - 6.7 7.0 10.5 11 6.3 10.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.10 GBG60365.1 - 9.1 5.5 29.5 13 5.0 29.5 1.1 1 0 0 1 1 1 0 BUD22 AF-4 PF05110.13 GBG60366.1 - 0.57 8.2 25.3 0.79 7.7 25.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DDHD PF02862.17 GBG60366.1 - 2.6 8.2 7.3 5.1 7.2 7.3 1.5 1 0 0 1 1 1 0 DDHD domain zf-CCHC PF00098.23 GBG60367.1 - 0.0059 16.6 1.9 0.0059 16.6 1.9 2.2 2 0 0 2 2 2 1 Zinc knuckle NINJA_B PF16136.5 GBG60367.1 - 0.4 11.1 13.3 0.86 10.0 13.3 1.7 1 1 0 1 1 1 0 Putative nuclear localisation signal Spore_III_AF PF09581.10 GBG60367.1 - 2.5 8.1 7.5 1.6 8.7 4.2 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DBINO PF13892.6 GBG60367.1 - 3 8.2 19.2 2.4 8.5 0.1 2.8 3 0 0 3 3 3 0 DNA-binding domain DUF4887 PF16228.5 GBG60368.1 - 0.11 12.6 7.5 0.16 12.2 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) P3A PF08727.11 GBG60368.1 - 0.12 11.8 0.1 0.27 10.6 0.1 1.6 1 0 0 1 1 1 0 Poliovirus 3A protein like PH_BEACH PF14844.6 GBG60368.1 - 0.14 12.2 0.9 0.31 11.2 0.9 1.5 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH DUF243 PF03103.17 GBG60368.1 - 0.98 9.8 4.4 0.96 9.8 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF243) DDRGK PF09756.9 GBG60368.1 - 1 8.9 16.0 0.17 11.5 11.8 1.7 1 1 1 2 2 2 0 DDRGK domain AAA_13 PF13166.6 GBG60368.1 - 1.1 7.8 8.5 1.4 7.5 8.5 1.1 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 GBG60369.1 - 5e-05 23.2 3.2 0.00012 22.0 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG60369.1 - 0.0038 16.8 0.0 1 8.8 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Transglut_core3 PF13471.6 GBG60369.1 - 0.024 14.6 0.2 2.2 8.2 0.0 3.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily zf-CCHC_2 PF13696.6 GBG60369.1 - 0.28 11.0 3.8 0.61 10.0 3.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Histone PF00125.24 GBG60370.1 - 2.5e-14 53.8 0.5 5.5e-14 52.6 0.5 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Kelch_4 PF13418.6 GBG60371.1 - 1.2e-35 121.3 7.5 1.3e-06 28.3 0.0 7.0 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG60371.1 - 3.6e-26 90.6 0.0 0.00019 21.4 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GBG60371.1 - 1.5e-21 76.1 22.5 2e-06 27.9 0.0 9.0 9 2 0 9 9 9 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GBG60371.1 - 3.8e-17 61.9 5.6 0.052 13.8 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_1 PF01344.25 GBG60371.1 - 7.1e-14 51.1 3.8 0.0032 17.0 0.1 7.0 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 GBG60371.1 - 6.5e-12 44.9 15.0 0.00061 19.7 0.0 6.8 7 0 0 7 7 7 3 Kelch motif F-box-like PF12937.7 GBG60371.1 - 0.00014 21.7 0.3 0.00014 21.7 0.3 2.9 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 GBG60371.1 - 0.00018 21.3 0.1 0.00067 19.5 0.1 2.0 1 0 0 1 1 1 1 F-box domain RVT_1 PF00078.27 GBG60372.1 - 4.6e-26 91.7 0.1 9e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60372.1 - 4.1e-22 78.1 0.0 1e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60372.1 - 3.6e-21 75.4 0.2 1.4e-20 73.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60372.1 - 1e-17 64.0 0.1 2.1e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60372.1 - 6.5e-08 32.8 0.0 2.8e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG60372.1 - 3.2e-07 30.2 0.0 8.3e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60372.1 - 2.4e-06 28.1 0.0 5.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60372.1 - 0.00026 21.5 0.0 0.0006 20.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG60372.1 - 0.00046 20.4 1.3 0.0033 17.7 0.1 3.2 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG60372.1 - 0.00072 19.7 0.0 0.011 16.0 0.0 2.8 3 0 0 3 3 3 1 H2C2 zinc finger Asp_protease PF09668.10 GBG60372.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease FAM76 PF16046.5 GBG60372.1 - 0.67 9.2 7.8 1.7 7.9 7.8 1.6 1 0 0 1 1 1 0 FAM76 protein DUF4391 PF14335.6 GBG60373.1 - 0.046 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) RVT_1 PF00078.27 GBG60374.1 - 4.8e-30 104.7 0.1 5.2e-29 101.3 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60374.1 - 2.1e-25 88.7 0.0 5.1e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60374.1 - 3e-24 85.3 0.0 9.7e-24 83.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG60374.1 - 1.5e-05 25.2 10.1 0.02 15.2 0.0 5.1 4 0 0 4 4 4 2 Retrotransposon gag protein Chromo PF00385.24 GBG60374.1 - 0.0068 16.3 0.1 0.019 14.8 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG60374.1 - 0.09 13.4 0.0 1.4 9.6 0.0 2.6 1 1 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG60374.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60374.1 - 0.17 11.7 0.0 0.91 9.3 0.0 2.0 1 1 0 1 1 1 0 Aspartyl protease NPV_P10 PF05531.12 GBG60374.1 - 2.4 8.7 8.4 14 6.2 0.3 3.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.13 GBG60374.1 - 5.9 6.4 7.8 84 2.7 2.4 3.6 3 0 0 3 3 3 0 fzo-like conserved region Myb_DNA-bind_4 PF13837.6 GBG60375.1 - 3.1e-06 27.5 2.0 5e-06 26.8 2.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Gmx_para_CXXCG PF09535.10 GBG60375.1 - 0.037 13.3 0.1 0.084 12.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Myb_DNA-bind_5 PF13873.6 GBG60375.1 - 0.68 10.1 4.0 1.9 8.6 4.0 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain SPRY PF00622.28 GBG60376.1 - 4.2e-28 97.9 0.0 1.3e-27 96.3 0.0 1.9 1 0 0 1 1 1 1 SPRY domain Ufd2P_core PF10408.9 GBG60376.1 - 8.4e-09 34.6 10.4 2.7e-07 29.6 1.3 2.9 2 1 0 2 2 2 2 Ubiquitin elongating factor core zf-C3HC4_3 PF13920.6 GBG60376.1 - 3e-06 27.0 11.0 6.7e-06 25.9 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG60376.1 - 0.0077 16.5 15.6 0.025 14.9 15.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG60376.1 - 0.011 15.6 14.7 0.029 14.3 14.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG60376.1 - 0.032 14.1 13.9 0.095 12.6 13.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG60376.1 - 0.089 12.7 10.8 0.23 11.4 10.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GBG60376.1 - 5 7.2 12.3 17 5.5 12.3 2.0 1 0 0 1 1 1 0 zinc-RING finger domain RT_RNaseH_2 PF17919.1 GBG60377.1 - 2.7e-20 72.3 0.0 5.4e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60377.1 - 4.8e-18 65.4 0.0 1.6e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60377.1 - 2.3e-10 40.7 0.0 5.2e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG60377.1 - 0.0032 18.1 0.0 0.009 16.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 GBG60377.1 - 0.013 15.3 0.0 0.038 13.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 GBG60377.1 - 0.014 15.9 0.1 0.036 14.6 0.1 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG60377.1 - 0.015 15.6 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Rx_N PF18052.1 GBG60377.1 - 0.067 13.5 0.9 14 6.0 0.1 3.4 3 0 0 3 3 3 0 Rx N-terminal domain DDE_1 PF03184.19 GBG60378.1 - 3.3e-23 82.2 1.0 1.4e-10 41.1 0.0 2.8 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 GBG60378.1 - 4.7e-09 36.2 0.9 8.8e-09 35.3 0.1 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 GBG60378.1 - 8.3e-06 26.0 2.3 2.1e-05 24.8 0.2 2.4 2 0 0 2 2 2 1 Transposase CENP-B_N PF04218.13 GBG60378.1 - 0.0043 16.7 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain E3_UbLigase_RBR PF18091.1 GBG60378.1 - 0.0092 16.1 0.0 3.3 7.9 0.0 2.5 2 0 0 2 2 2 2 E3 Ubiquitin Ligase RBR C-terminal domain DUF4207 PF13904.6 GBG60378.1 - 0.039 13.6 1.5 0.064 12.9 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Thioredoxin_6 PF13848.6 GBG60378.1 - 0.044 13.7 0.2 7.5 6.4 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin-like domain WhiA_N PF10298.9 GBG60378.1 - 0.078 13.0 0.0 19 5.4 0.0 2.7 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain DUF3027 PF11228.8 GBG60379.1 - 0.67 9.9 5.8 0.86 9.6 4.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3027) RVT_1 PF00078.27 GBG60380.1 - 9.2e-28 97.3 0.1 1.6e-27 96.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyl-CoA_dh_N PF02771.16 GBG60380.1 - 3.4e-19 69.6 0.1 2.3e-15 57.3 0.0 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, N-terminal domain Integrase_H2C2 PF17921.1 GBG60380.1 - 5.8e-15 55.1 0.1 1.7e-14 53.6 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Acyl-CoA_dh_M PF02770.19 GBG60380.1 - 7.7e-14 51.7 0.0 4e-13 49.4 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain rve PF00665.26 GBG60380.1 - 6.4e-08 32.8 0.0 2e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG60380.1 - 0.096 12.6 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG60380.1 - 0.097 13.0 0.3 0.54 10.6 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Rz1 PF06085.11 GBG60380.1 - 0.23 11.2 1.3 0.58 10.0 1.3 1.7 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor RT_RNaseH_2 PF17919.1 GBG60382.1 - 3.1e-31 107.3 0.0 5.1e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60382.1 - 1.1e-29 102.8 0.0 2e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Acyl-CoA_dh_1 PF00441.24 GBG60382.1 - 4.3e-25 88.7 0.1 8.4e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GBG60382.1 - 0.0012 19.0 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GBG60382.1 - 0.028 14.7 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Phage_GPO PF05929.11 GBG60382.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH PF17917.1 GBG60383.1 - 2.1e-22 79.4 0.0 4.7e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60383.1 - 8.2e-21 73.9 0.0 1.9e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60383.1 - 5.6e-19 68.0 0.1 1.3e-18 66.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60383.1 - 1e-09 38.6 0.0 3.7e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG60383.1 - 4e-08 33.1 0.7 5.7e-07 29.3 0.0 2.5 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG60383.1 - 7.2e-07 29.8 0.0 1.7e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60383.1 - 1e-06 28.6 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60383.1 - 6e-06 26.7 0.0 1.7e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG60383.1 - 0.0073 16.6 0.3 0.051 13.9 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein SlyX PF04102.12 GBG60383.1 - 0.026 15.1 0.3 0.026 15.1 0.3 4.2 4 0 0 4 4 3 0 SlyX Asp_protease PF09668.10 GBG60383.1 - 0.027 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Rab_bind PF16704.5 GBG60383.1 - 1.1 9.4 4.0 0.54 10.3 0.1 2.5 2 0 0 2 2 2 0 Rab binding domain RVT_1 PF00078.27 GBG60384.1 - 2.1e-30 105.9 0.1 3.2e-30 105.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60384.1 - 4.1e-27 94.1 0.0 1.2e-26 92.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60384.1 - 3e-24 85.3 0.0 7.4e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG60384.1 - 0.0002 21.9 0.0 0.00045 20.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60384.1 - 0.00049 20.6 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG60384.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60384.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG60385.1 - 2.5e-25 88.4 0.0 4.6e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60385.1 - 1.5e-22 79.9 0.0 3.2e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG60385.1 - 1.5e-05 24.8 0.3 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60385.1 - 0.00049 20.6 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60385.1 - 0.002 18.7 0.0 0.0094 16.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG60385.1 - 0.011 16.1 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Ku_N PF03731.15 GBG60385.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain RT_RNaseH_2 PF17919.1 GBG60387.1 - 4e-22 78.1 0.0 7e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60387.1 - 2.7e-20 72.6 0.0 5.6e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60389.1 - 2.3e-33 114.2 0.0 4.8e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60389.1 - 1.7e-30 106.2 0.0 2.9e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60389.1 - 2.8e-30 104.7 0.2 8.1e-30 103.2 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60389.1 - 3.5e-18 65.5 0.1 8.9e-18 64.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain MLTR_LBD PF17765.1 GBG60390.1 - 0.18 11.9 0.1 0.26 11.4 0.1 1.2 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain gag-asp_proteas PF13975.6 GBG60391.1 - 8.5e-07 29.4 0.0 2.1e-05 25.0 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60391.1 - 1.8e-06 28.5 0.0 5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60391.1 - 6.8e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60391.1 - 0.00072 19.3 0.0 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG60392.1 - 4.5e-28 98.3 0.1 9.6e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60392.1 - 2.6e-16 59.8 0.0 6.5e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60392.1 - 8.2e-10 38.6 0.0 2.2e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60392.1 - 2.2e-07 31.4 0.0 6.3e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60392.1 - 2.4e-07 31.3 0.0 6.1e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG60392.1 - 7.5e-05 22.9 0.1 0.00027 21.1 0.1 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG60392.1 - 0.00018 21.3 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60392.1 - 0.00021 21.1 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease TSC22 PF01166.18 GBG60392.1 - 1.7 9.0 5.3 0.58 10.5 0.1 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family RT_RNaseH_2 PF17919.1 GBG60393.1 - 7.7e-25 86.8 0.0 2e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60393.1 - 4.2e-23 81.6 0.1 1.3e-22 80.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60393.1 - 3.8e-18 65.3 1.0 8.7e-18 64.2 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG60393.1 - 1.1e-11 44.7 1.2 4.5e-06 26.3 0.2 3.4 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60393.1 - 6.6e-07 29.5 0.0 1.9e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG60393.1 - 0.00058 20.1 12.3 0.0036 17.5 0.0 4.6 4 0 0 4 4 4 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG60393.1 - 0.0012 19.4 0.0 0.003 18.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60393.1 - 0.0019 18.8 0.0 0.005 17.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG60393.1 - 0.03 14.5 0.1 0.34 11.2 0.0 2.8 3 0 0 3 3 3 0 H2C2 zinc finger DUF4407 PF14362.6 GBG60393.1 - 3.7 6.8 13.5 5.6 6.2 6.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 GBG60393.1 - 4 8.1 5.4 6.4 7.4 0.7 3.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Mlo PF03094.15 GBG60395.1 - 8.6e-97 324.5 0.7 8.6e-97 324.5 0.7 1.6 2 0 0 2 2 1 1 Mlo family RT_RNaseH PF17917.1 GBG60395.1 - 5.2e-24 84.5 0.0 1.3e-23 83.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60395.1 - 5.7e-23 80.8 0.0 1.3e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60395.1 - 7.1e-19 67.7 0.1 1.7e-18 66.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG60395.1 - 1.4e-06 28.1 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG60395.1 - 0.00029 21.1 0.1 0.0089 16.3 0.0 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG60395.1 - 0.00063 20.3 0.0 0.002 18.7 0.0 1.9 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60395.1 - 0.0079 16.7 0.0 0.02 15.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60395.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease LMBR1 PF04791.16 GBG60395.1 - 2.2 7.1 8.0 4.7 6.0 8.0 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Zip PF02535.22 GBG60395.1 - 4 6.6 7.3 29 3.7 5.6 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter PAF PF15715.5 GBG60395.1 - 6.6 7.3 14.6 20 5.8 14.6 1.7 1 0 0 1 1 1 0 PCNA-associated factor histone like domain RVT_1 PF00078.27 GBG60396.1 - 3e-48 164.3 0.1 7.8e-27 94.2 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60396.1 - 1.8e-15 56.8 0.2 1.6e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase DUF5095 PF17016.5 GBG60396.1 - 0.014 15.1 0.6 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) RT_RNaseH PF17917.1 GBG60396.1 - 0.025 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF3863 PF12979.7 GBG60396.1 - 0.088 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) zf-CCHC PF00098.23 GBG60397.1 - 4.8e-07 29.5 2.2 1.7e-06 27.8 2.2 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-Mss51 PF13824.6 GBG60397.1 - 0.039 14.1 2.4 3.4 7.8 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Prok-RING_1 PF14446.6 GBG60397.1 - 0.21 11.6 2.7 0.14 12.1 0.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-CCHC_2 PF13696.6 GBG60397.1 - 1.7 8.5 8.9 0.22 11.4 2.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCCH PF00642.24 GBG60398.1 - 6.5e-41 137.5 47.7 2.8e-10 39.9 2.7 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG60398.1 - 9.6e-19 66.8 65.7 0.0002 21.3 7.3 5.6 6 0 0 6 6 6 5 Zinc finger domain zf-CCCH_4 PF18044.1 GBG60398.1 - 9.4e-18 63.6 53.0 0.00018 21.2 6.7 5.4 5 0 0 5 5 5 5 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GBG60398.1 - 0.0001 22.7 47.2 0.062 13.8 2.0 5.7 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GBG60398.1 - 0.00016 22.3 29.7 1 10.1 0.3 5.4 4 1 0 5 5 5 4 Torus domain CENP-B_dimeris PF09026.10 GBG60398.1 - 5.5 7.5 9.8 9.7 6.7 9.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF659 PF04937.15 GBG60399.1 - 1.4e-30 106.2 0.0 2.1e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60399.1 - 0.0022 17.7 0.3 0.0072 16.1 0.2 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RR_TM4-6 PF06459.12 GBG60399.1 - 0.98 9.2 5.7 12 5.7 5.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4207 PF13904.6 GBG60399.1 - 4.1 7.0 13.2 0.21 11.2 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Integrase_H2C2 PF17921.1 GBG60403.1 - 3.4e-11 43.1 0.1 1.2e-10 41.3 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60403.1 - 1.9e-10 40.9 0.0 4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Bap31_Bap29_C PF18035.1 GBG60403.1 - 0.04 13.9 1.9 0.1 12.6 1.9 1.7 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1664 PF07889.12 GBG60404.1 - 0.013 15.5 4.1 0.013 15.5 4.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) APOBEC_C PF05240.14 GBG60404.1 - 0.058 13.3 2.1 0.073 13.0 0.3 2.1 2 0 0 2 2 2 0 APOBEC-like C-terminal domain LMBR1 PF04791.16 GBG60404.1 - 0.12 11.3 15.3 0.33 9.8 15.3 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein DNA_pack_N PF02500.15 GBG60404.1 - 2.9 7.7 7.6 0.83 9.4 0.1 2.2 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus DUF5069 PF16798.5 GBG60404.1 - 7.1 6.8 11.6 0.36 11.0 1.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) Tab2_like PF06485.11 GBG60405.1 - 3.7e-41 141.4 0.0 4.1e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 RNA-binding protein Tab2/Atab2 Peptidase_M2 PF01401.18 GBG60405.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme RVP_2 PF08284.11 GBG60406.1 - 1.3e-07 31.4 0.0 2.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60406.1 - 3.6e-06 27.5 0.0 9.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60406.1 - 0.00047 20.7 0.0 0.0019 18.7 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG60406.1 - 0.069 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG60406.1 - 0.17 11.7 0.0 5.1 6.9 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.27 GBG60407.1 - 1.2e-27 96.9 0.0 3.1e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60407.1 - 8.2e-24 83.6 0.0 2.5e-23 82.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60407.1 - 3.3e-18 65.9 0.0 9e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG60407.1 - 2.9e-06 27.9 0.0 7.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60407.1 - 8.4e-06 26.3 0.0 2.5e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60407.1 - 0.00034 20.4 0.0 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG60407.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG60407.1 - 0.015 15.6 1.6 0.28 11.5 0.0 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein RVP_2 PF08284.11 GBG60409.1 - 5.2e-10 39.2 0.0 1.6e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60409.1 - 5.8e-06 26.9 0.0 2.3e-05 25.0 0.0 2.0 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60409.1 - 2.9e-05 24.5 0.0 9.1e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG60409.1 - 0.00013 22.1 0.5 0.0016 18.7 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG60409.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TolA_bind_tri PF16331.5 GBG60409.1 - 0.02 15.0 3.5 0.02 15.0 3.5 1.9 1 1 1 2 2 2 0 TolA binding protein trimerisation Cast PF10174.9 GBG60409.1 - 0.027 12.7 1.5 0.04 12.2 1.5 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ADIP PF11559.8 GBG60409.1 - 0.041 14.0 1.5 0.073 13.2 1.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 GBG60409.1 - 0.07 13.6 1.0 0.13 12.7 1.0 1.4 1 0 0 1 1 1 0 Fez1 DUF16 PF01519.16 GBG60409.1 - 0.095 13.2 4.5 0.11 13.0 1.4 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 COPR5 PF15340.6 GBG60409.1 - 0.15 12.7 1.9 0.2 12.3 0.7 1.8 2 0 0 2 2 2 0 Cooperator of PRMT5 family TMF_DNA_bd PF12329.8 GBG60409.1 - 0.18 11.8 0.3 0.56 10.2 0.1 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.12 GBG60409.1 - 0.2 11.7 3.5 0.49 10.4 3.5 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 GBG60409.1 - 5.4 7.7 10.8 0.58 10.8 2.3 2.9 2 1 1 3 3 3 0 SlyX rve PF00665.26 GBG60410.1 - 3.3e-11 43.4 0.0 8.3e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG60410.1 - 0.00016 21.5 0.2 0.00034 20.5 0.0 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG60410.1 - 0.0028 17.9 0.2 0.0028 17.9 0.2 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein TFIIA PF03153.13 GBG60410.1 - 0.3 11.0 6.8 0.72 9.8 6.8 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 GBG60410.1 - 1.9 7.8 17.2 3.7 6.8 16.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 GBG60410.1 - 5.8 4.3 11.4 7.6 3.9 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) Tab2_like PF06485.11 GBG60412.1 - 5.3e-33 114.7 0.2 7.1e-33 114.3 0.2 1.1 1 0 0 1 1 1 1 RNA-binding protein Tab2/Atab2 PTS_IIB PF02302.17 GBG60412.1 - 0.26 12.0 0.9 1.6 9.5 0.6 2.3 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit RT_RNaseH_2 PF17919.1 GBG60413.1 - 9.6e-29 99.4 0.0 3.2e-15 56.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60413.1 - 1.2e-27 96.3 0.0 2.3e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60413.1 - 4.4e-26 91.8 0.0 7.6e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG60413.1 - 4e-11 42.7 0.1 1.1e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG60413.1 - 0.013 16.1 0.0 0.033 14.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG60414.1 - 1.2e-19 70.6 0.0 3e-19 69.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG60415.1 - 1.4e-19 70.0 0.0 2.7e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60415.1 - 4.5e-18 65.5 0.0 1.2e-17 64.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG60415.1 - 0.00044 20.5 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60415.1 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60415.1 - 0.0017 18.9 0.0 0.005 17.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60415.1 - 0.0053 17.4 0.0 0.018 15.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG60415.1 - 0.0089 16.3 0.1 0.047 14.0 0.1 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG60416.1 - 5.2e-17 62.1 0.2 1.7e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60416.1 - 7.5e-17 61.2 0.7 2.3e-16 59.6 0.7 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG60416.1 - 5.1e-14 52.1 0.0 1.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60416.1 - 9.4e-07 29.3 0.0 2.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60416.1 - 1.8e-05 25.3 0.0 4.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60416.1 - 7.6e-05 22.5 0.1 0.00014 21.6 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG60416.1 - 0.042 13.5 0.1 0.097 12.4 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like rve PF00665.26 GBG60416.1 - 0.083 13.1 0.0 0.32 11.2 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain RVP_2 PF08284.11 GBG60416.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG60416.1 - 0.2 11.9 1.2 0.45 10.8 0.3 2.1 2 0 0 2 2 2 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG60417.1 - 0.071 13.4 0.0 0.3 11.4 0.0 2.2 1 1 0 1 1 1 0 Retrotransposon gag protein DUF4604 PF15377.6 GBG60417.1 - 0.33 11.4 22.2 1.1 9.7 4.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Presenilin PF01080.17 GBG60417.1 - 6.9 5.3 11.1 0.45 9.2 2.0 2.1 2 0 0 2 2 2 0 Presenilin DUF659 PF04937.15 GBG60418.1 - 2e-25 89.4 0.1 6.1e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60419.1 - 5e-08 32.6 0.4 8.9e-08 31.8 0.4 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nop14 PF04147.12 GBG60419.1 - 0.054 11.7 18.4 0.065 11.5 18.4 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG60419.1 - 0.2 11.5 14.7 0.29 10.9 14.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 GBG60419.1 - 0.24 9.5 8.2 0.29 9.2 8.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 GBG60419.1 - 0.49 10.4 3.4 0.66 10.0 3.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PPP4R2 PF09184.11 GBG60419.1 - 0.6 9.6 13.4 0.83 9.2 13.4 1.3 1 0 0 1 1 1 0 PPP4R2 DUF1387 PF07139.11 GBG60419.1 - 0.63 9.7 14.0 0.9 9.2 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SDA1 PF05285.12 GBG60419.1 - 0.85 9.0 23.7 1.2 8.5 23.7 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG60419.1 - 1.2 7.8 9.9 1.5 7.5 9.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.13 GBG60419.1 - 1.6 7.7 20.6 2.4 7.1 20.6 1.3 1 0 0 1 1 1 0 Paf1 Lin-8 PF03353.15 GBG60419.1 - 1.6 8.2 17.5 2.2 7.8 17.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NPR3 PF03666.13 GBG60419.1 - 2 7.1 14.6 2.8 6.6 14.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GBG60419.1 - 4.9 5.8 19.3 7.6 5.2 19.3 1.2 1 0 0 1 1 1 0 Presenilin TAXi_N PF14543.6 GBG60420.1 - 5.6e-35 121.2 1.1 9.6e-35 120.4 1.1 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GBG60420.1 - 5.4e-32 111.5 0.0 2.3e-31 109.4 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GBG60420.1 - 2.3e-24 86.0 0.0 4.6e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal RVT_1 PF00078.27 GBG60420.1 - 4e-10 39.6 0.0 9.4e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4187 PF13821.6 GBG60421.1 - 0.0021 17.8 0.5 0.0071 16.1 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG60421.1 - 0.0025 18.1 0.2 0.0025 18.1 0.2 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein DUF3584 PF12128.8 GBG60421.1 - 0.0076 13.8 1.1 0.011 13.3 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Lipin_mid PF16876.5 GBG60421.1 - 0.022 14.9 1.3 0.14 12.3 0.0 2.5 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain NAD_binding_8 PF13450.6 GBG60423.1 - 8.7e-13 48.3 0.3 3.2e-12 46.5 0.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GBG60423.1 - 1.9e-09 37.4 0.0 2.2e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 GBG60423.1 - 3.6e-09 36.7 1.0 2.6e-08 33.8 1.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG60423.1 - 2.4e-07 30.2 2.3 2.4e-07 30.2 2.3 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GBG60423.1 - 1.4e-05 24.6 0.9 1.4e-05 24.6 0.9 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GBG60423.1 - 2.7e-05 23.4 3.3 0.0046 16.1 1.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GBG60423.1 - 3.5e-05 23.2 0.6 3.5e-05 23.2 0.6 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GBG60423.1 - 0.00022 20.6 0.9 0.00048 19.4 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GBG60423.1 - 0.00023 20.5 2.1 0.00025 20.4 0.2 1.8 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 GBG60423.1 - 0.00072 18.9 0.2 0.0014 18.0 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GDI PF00996.18 GBG60423.1 - 0.0033 16.0 0.0 0.28 9.6 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor Pyr_redox_3 PF13738.6 GBG60423.1 - 0.01 15.1 0.0 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 GBG60423.1 - 0.011 15.2 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 GMC oxidoreductase UDPG_MGDP_dh_N PF03721.14 GBG60423.1 - 0.035 13.7 0.2 0.075 12.6 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 GBG60423.1 - 0.038 12.7 5.4 0.019 13.7 1.0 2.3 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 GBG60423.1 - 0.052 14.1 2.3 0.052 14.1 0.7 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GBG60423.1 - 3.4 6.6 4.6 1.6 7.7 2.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein RT_RNaseH_2 PF17919.1 GBG60424.1 - 7.9e-21 74.0 0.0 1.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60424.1 - 3.2e-19 69.1 0.0 9e-19 67.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60424.1 - 6.7e-12 45.6 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG60424.1 - 1.5e-08 34.6 0.1 4.5e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG60424.1 - 0.0052 16.5 0.0 0.018 14.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Fur_reg_FbpB PF13040.6 GBG60424.1 - 0.16 11.6 0.8 0.44 10.1 0.8 1.7 1 0 0 1 1 1 0 Fur-regulated basic protein B Integrase_H2C2 PF17921.1 GBG60425.1 - 2.9e-11 43.3 0.2 5.3e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60425.1 - 1.1e-08 35.2 0.0 3.5e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HIP1_clath_bdg PF16515.5 GBG60425.1 - 1.6 9.4 6.0 0.45 11.2 1.9 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF659 PF04937.15 GBG60426.1 - 4e-25 88.5 0.5 7.2e-25 87.6 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60426.1 - 0.00043 20.0 0.2 0.0012 18.5 0.2 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCHC_4 PF14392.6 GBG60427.1 - 0.095 12.5 2.0 0.19 11.5 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Nucleo_P87 PF07267.11 GBG60427.1 - 0.68 8.7 3.5 1.3 7.8 3.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RVT_1 PF00078.27 GBG60428.1 - 1.7e-05 24.4 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) cobW PF02492.19 GBG60429.1 - 3.9e-42 143.8 1.1 6.3e-42 143.2 1.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GBG60429.1 - 1.1e-13 50.9 0.0 2.4e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 GBG60429.1 - 0.00036 21.0 0.0 0.00094 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 GBG60429.1 - 0.0049 16.9 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 GBG60429.1 - 0.0058 16.6 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 GBG60429.1 - 0.01 16.0 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 GBG60429.1 - 0.011 14.8 0.3 0.03 13.3 0.3 1.7 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 GBG60429.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GBG60429.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG60429.1 - 0.053 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 GBG60429.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG60429.1 - 0.17 11.8 0.1 0.89 9.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain TerC PF03741.16 GBG60430.1 - 2.7e-33 115.2 5.4 4.6e-33 114.4 5.4 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family RVT_1 PF00078.27 GBG60430.1 - 2.1e-31 109.2 0.0 5.3e-31 107.9 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60430.1 - 1.1e-30 105.7 0.0 6.2e-30 103.2 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60430.1 - 1.4e-30 105.7 0.1 9.3e-30 103.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60430.1 - 1.3e-18 66.8 0.7 3.1e-18 65.6 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60430.1 - 2.4e-15 56.8 0.0 6.1e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG60430.1 - 0.0068 16.6 0.3 0.019 15.2 0.1 1.9 2 0 0 2 2 2 1 H2C2 zinc finger PHTB1_C PF14728.6 GBG60431.1 - 3.1e-33 115.4 0.5 4e-33 115.0 0.5 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus Trimer_CC PF08954.11 GBG60431.1 - 0.012 15.2 0.9 0.024 14.2 0.9 1.5 1 0 0 1 1 1 0 Trimerisation motif PspA_IM30 PF04012.12 GBG60431.1 - 0.049 13.2 3.2 0.1 12.2 0.8 2.1 1 1 1 2 2 2 0 PspA/IM30 family Spatacsin_C PF14649.6 GBG60432.1 - 1.6e-72 244.2 0.1 2.4e-72 243.6 0.1 1.3 1 0 0 1 1 1 1 Spatacsin C-terminus DUF3138 PF11336.8 GBG60433.1 - 0.19 10.3 2.9 0.2 10.2 2.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF2950 PF11453.8 GBG60433.1 - 0.29 10.3 9.1 0.41 9.8 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) BAF1_ABF1 PF04684.13 GBG60433.1 - 2.5 7.1 15.1 3.2 6.7 15.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RabGAP-TBC PF00566.18 GBG60435.1 - 1.7e-50 171.6 6.5 2.2e-50 171.3 6.5 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 GBG60435.1 - 5.3e-11 42.3 0.0 9.5e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Rab-binding domain (RBD) Yae1_N PF09811.9 GBG60435.1 - 0.032 13.9 23.6 12 5.7 0.0 7.6 6 2 3 9 9 9 0 Essential protein Yae1, N terminal Yae1_N PF09811.9 GBG60436.1 - 0.056 13.1 2.5 16 5.3 1.1 4.4 1 1 2 3 3 3 0 Essential protein Yae1, N terminal Fucose_iso_N1 PF07881.12 GBG60437.1 - 0.034 14.0 0.1 0.059 13.2 0.1 1.3 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain RT_RNaseH_2 PF17919.1 GBG60438.1 - 5.5e-27 93.7 0.1 1.4e-26 92.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60438.1 - 1.3e-25 89.6 0.1 3e-25 88.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Herpes_BLRF2 PF05812.12 GBG60438.1 - 0.011 15.9 0.2 0.026 14.6 0.2 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Prp19 PF08606.11 GBG60438.1 - 0.12 12.4 1.0 0.46 10.5 1.0 2.0 1 0 0 1 1 1 0 Prp19/Pso4-like PEP-utilisers_N PF05524.13 GBG60438.1 - 0.57 10.4 3.9 8.7 6.5 0.1 3.6 2 1 2 4 4 4 0 PEP-utilising enzyme, N-terminal PH_RBD PF12068.8 GBG60439.1 - 3.9e-12 46.0 0.0 2.2e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Rab-binding domain (RBD) PH_RBD PF12068.8 GBG60440.1 - 4.4e-12 45.8 0.0 3.4e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Rab-binding domain (RBD) PI3Ka PF00613.20 GBG60441.1 - 7e-63 211.4 2.1 1.7e-62 210.1 0.6 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GBG60441.1 - 2.7e-21 76.5 0.0 4.9e-13 49.5 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 GBG60441.1 - 1.5e-20 73.6 0.0 2.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4070 PF13282.6 GBG60441.1 - 0.053 13.7 0.1 0.9 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) RVT_1 PF00078.27 GBG60442.1 - 9.7e-31 107.0 0.0 1.5e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60442.1 - 2.3e-30 104.9 0.0 5.4e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60442.1 - 1.8e-29 101.7 0.0 5.9e-14 51.9 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60442.1 - 1.3e-15 57.2 0.1 5.4e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG60442.1 - 2.8e-13 50.1 0.0 1.2e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG60442.1 - 2.8e-05 24.2 0.0 6.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Apt1 PF10351.9 GBG60443.1 - 2.3 7.0 5.1 2.4 6.9 5.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RT_RNaseH_2 PF17919.1 GBG60444.1 - 7.3e-15 54.8 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60444.1 - 1.2e-12 48.0 0.0 3.1e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60444.1 - 6.1e-07 29.2 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG60444.1 - 5.8e-06 26.8 0.4 1.7e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60444.1 - 0.00018 22.1 0.0 0.00055 20.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60444.1 - 0.15 11.9 4.2 0.048 13.4 1.0 1.8 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 GBG60444.1 - 0.17 12.2 0.0 0.54 10.6 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2753 PF10952.8 GBG60445.1 - 0.16 12.1 1.0 0.45 10.6 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2753) FYVE PF01363.21 GBG60446.1 - 0.16 12.1 4.2 0.31 11.2 4.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_2 PF13639.6 GBG60446.1 - 1 9.8 10.7 2.1 8.8 10.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 GBG60446.1 - 2.7 7.9 9.2 5.4 7.0 9.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 GBG60447.1 - 3.1e-07 30.1 2.5 7.7e-07 28.9 2.5 1.7 1 0 0 1 1 1 1 Zinc knuckle HAUS-augmin3 PF14932.6 GBG60447.1 - 0.044 13.3 9.5 0.071 12.7 9.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 zf-CCHC_4 PF14392.6 GBG60447.1 - 0.14 11.9 0.6 0.29 10.9 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle SpoVR PF04293.13 GBG60447.1 - 0.17 10.5 7.0 0.24 10.1 7.0 1.1 1 0 0 1 1 1 0 SpoVR like protein SprA-related PF12118.8 GBG60447.1 - 0.21 10.7 8.1 0.29 10.3 8.1 1.2 1 0 0 1 1 1 0 SprA-related family Peptidase_S64 PF08192.11 GBG60447.1 - 0.69 8.3 5.7 0.93 7.9 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 SmAKAP PF15127.6 GBG60447.1 - 1.3 10.3 9.5 5.7 8.2 9.5 2.1 1 0 0 1 1 1 0 Small membrane A-kinase anchor protein RP-C_C PF11800.8 GBG60447.1 - 1.9 8.5 10.3 1.7 8.7 7.0 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Borrelia_P83 PF05262.11 GBG60447.1 - 2.3 6.6 19.1 3.4 6.1 19.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1682 PF07946.14 GBG60447.1 - 2.3 7.3 24.4 3.6 6.7 24.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Folliculin PF11704.8 GBG60447.1 - 2.8 7.8 7.3 7.6 6.4 7.3 1.7 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Hid1 PF12722.7 GBG60447.1 - 3.3 5.7 7.4 4.5 5.3 7.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GST_C_2 PF13410.6 GBG60448.1 - 3.4e-10 39.8 0.0 5.2e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GBG60448.1 - 1.3e-07 31.8 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GBG60448.1 - 9.8e-06 25.7 0.1 1.5e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRN3 PF05327.11 GBG60449.1 - 0.054 12.0 6.5 0.057 12.0 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GBG60449.1 - 0.2 9.8 22.2 0.24 9.6 22.2 1.1 1 0 0 1 1 1 0 Nop14-like family UPF0167 PF03691.14 GBG60449.1 - 0.28 11.0 2.6 0.19 11.5 0.2 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) Merozoite_SPAM PF07133.11 GBG60449.1 - 4.8 7.2 39.0 7.2 6.6 39.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.12 GBG60450.1 - 0.088 11.0 22.2 0.092 11.0 22.2 1.1 1 0 0 1 1 1 0 Nop14-like family UPF0167 PF03691.14 GBG60450.1 - 0.089 12.6 0.2 0.089 12.6 0.2 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) RRN3 PF05327.11 GBG60450.1 - 1.8 7.0 12.5 2.1 6.8 12.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Merozoite_SPAM PF07133.11 GBG60450.1 - 5.2 7.0 40.1 6.9 6.6 40.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RRP7 PF12923.7 GBG60451.1 - 8.4e-05 22.7 6.8 0.00014 22.0 6.8 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain FAM176 PF14851.6 GBG60451.1 - 0.0095 15.6 1.3 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 FAM176 family WRNPLPNID PF15017.6 GBG60451.1 - 0.011 16.6 4.7 0.011 16.6 4.7 2.2 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box OAD_gamma PF04277.13 GBG60451.1 - 0.019 15.5 0.8 0.62 10.7 0.5 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PsaL PF02605.15 GBG60451.1 - 0.033 13.8 0.0 0.97 9.1 0.0 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI SLAIN PF15301.6 GBG60451.1 - 0.033 13.4 1.7 0.051 12.8 1.7 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family SspB PF04386.13 GBG60451.1 - 0.071 13.0 0.7 0.1 12.5 0.7 1.3 1 0 0 1 1 1 0 Stringent starvation protein B Chorein_N PF12624.7 GBG60451.1 - 0.19 11.8 6.1 3.3 7.8 0.6 2.2 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 EphA2_TM PF14575.6 GBG60451.1 - 0.21 12.5 0.3 15 6.6 0.4 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DASH_Spc19 PF08287.11 GBG60451.1 - 0.28 11.1 6.2 0.56 10.1 0.3 2.1 2 0 0 2 2 2 0 Spc19 Rsc14 PF08586.10 GBG60451.1 - 0.29 12.0 3.2 13 6.7 0.5 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit E7 PF00527.18 GBG60451.1 - 0.44 10.8 3.9 3 8.1 3.1 2.2 2 0 0 2 2 2 0 E7 protein, Early protein RNA_pol_3_Rpc31 PF11705.8 GBG60451.1 - 1.5 9.0 16.6 1.6 9.0 4.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 AP3D1 PF06375.11 GBG60451.1 - 4.6 7.5 17.4 5.7 7.2 12.3 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 TFB6 PF17110.5 GBG60451.1 - 6.9 6.4 6.8 17 5.1 6.8 1.6 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Peptidase_S49_N PF08496.10 GBG60451.1 - 10 6.2 9.9 19 5.3 8.0 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PC-Esterase PF13839.6 GBG60452.1 - 1.3e-25 90.7 0.0 6.3e-23 81.9 0.0 2.3 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 GBG60452.1 - 8.7e-08 32.4 2.9 2.1e-07 31.1 2.9 1.7 1 0 0 1 1 1 1 PMR5 N terminal Domain RVT_1 PF00078.27 GBG60453.1 - 4.9e-30 104.7 0.0 8e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG60453.1 - 1.2e-09 38.0 0.0 3.2e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG60453.1 - 0.014 16.0 0.0 0.032 14.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease PAC3 PF10178.9 GBG60454.1 - 3.6e-19 68.7 0.0 5.1e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 HD PF01966.22 GBG60455.1 - 3.1e-07 30.6 0.1 3.5e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 GBG60455.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 HDOD domain MWFE PF15879.5 GBG60456.1 - 2.9e-10 40.1 0.0 3.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Integrase_H2C2 PF17921.1 GBG60458.1 - 4.6e-20 71.5 0.1 9e-20 70.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG60458.1 - 4.7e-17 62.2 0.0 8.9e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60458.1 - 2e-14 53.8 0.0 4.2e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG60458.1 - 4.4e-08 33.1 0.2 9e-08 32.1 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG60458.1 - 0.00093 19.4 0.0 0.0029 17.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RAP1 PF07218.11 GBG60458.1 - 0.8 7.9 2.5 1.2 7.4 2.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF659 PF04937.15 GBG60461.1 - 4.6e-14 52.6 0.0 6.9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG60462.1 - 2.8e-28 98.9 0.1 4.6e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG60462.1 - 1.9e-05 24.5 2.1 4.9e-05 23.2 2.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG60462.1 - 1.1 9.2 4.5 0.68 9.8 1.9 2.1 2 0 0 2 2 2 0 Zinc knuckle HalX PF08663.10 GBG60462.1 - 3.1 8.2 14.9 1.8 8.9 0.2 4.3 4 0 0 4 4 4 0 HalX domain RCDG1 PF15725.5 GBG60462.1 - 9.4 6.7 10.8 34 5.0 10.8 1.9 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein DUF659 PF04937.15 GBG60463.1 - 6.9e-21 74.7 0.0 9.7e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG60464.1 - 8e-13 48.6 0.0 1.9e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG60464.1 - 0.0027 17.4 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) HAUS6_N PF14661.6 GBG60464.1 - 0.32 10.5 2.2 0.78 9.3 0.8 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4140 PF13600.6 GBG60464.1 - 10 6.7 6.8 1.3 9.5 2.4 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) gag-asp_proteas PF13975.6 GBG60465.1 - 7e-07 29.7 0.0 1.6e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60465.1 - 5.4e-05 23.8 0.1 0.00013 22.5 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60465.1 - 0.006 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60465.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG60465.1 - 0.063 13.4 1.9 0.15 12.2 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG60465.1 - 0.08 12.6 1.9 0.091 12.4 0.3 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like GTP_cyclohydroI PF01227.22 GBG60466.1 - 5.3e-51 172.6 6.1 3.7e-27 94.9 0.0 3.3 3 0 0 3 3 3 3 GTP cyclohydrolase I DUF5610 PF18433.1 GBG60466.1 - 0.00034 21.1 4.9 1.8 9.1 0.0 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF5610) VWA PF00092.28 GBG60466.1 - 0.0022 18.3 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4148 PF13663.6 GBG60466.1 - 3.7 7.8 4.7 74 3.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) VWA PF00092.28 GBG60467.1 - 0.00024 21.4 0.0 0.00035 20.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain CAT PF00302.18 GBG60468.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase DUF659 PF04937.15 GBG60469.1 - 1e-29 103.4 0.1 1.6e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60469.1 - 0.00017 21.3 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RRM_1 PF00076.22 GBG60470.1 - 0.00026 20.7 0.2 0.8 9.6 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_4 PF13837.6 GBG60471.1 - 4.7e-09 36.5 0.3 9.9e-09 35.5 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG60471.1 - 0.024 14.7 2.2 0.059 13.5 2.2 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RR_TM4-6 PF06459.12 GBG60472.1 - 4.8 6.9 7.2 5.7 6.7 7.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nup188 PF10487.9 GBG60473.1 - 4.7e-38 130.8 0.0 4.4e-29 101.1 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Nup192 PF11894.8 GBG60473.1 - 8.6e-13 46.4 7.4 1.9e-09 35.4 0.1 3.3 2 1 1 3 3 3 3 Nuclear pore complex scaffold, nucleoporins 186/192/205 gag-asp_proteas PF13975.6 GBG60474.1 - 1.8e-06 28.4 0.0 6.5e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60474.1 - 0.00036 21.1 0.3 0.0017 19.0 0.0 2.3 3 0 0 3 3 3 1 Aspartyl protease RVP PF00077.20 GBG60474.1 - 0.023 15.0 0.0 0.055 13.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60474.1 - 0.046 13.5 0.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease DUF913 PF06025.12 GBG60474.1 - 0.22 10.5 3.0 5.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) ICA69 PF04629.14 GBG60474.1 - 0.87 9.8 7.2 1.5 9.1 7.2 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain Semialdhyde_dh PF01118.24 GBG60475.1 - 2.4e-28 99.0 0.0 4.8e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 GBG60475.1 - 3e-17 63.3 0.0 7e-17 62.1 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Sacchrp_dh_NADP PF03435.18 GBG60475.1 - 0.15 12.3 0.4 0.61 10.4 0.0 2.3 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain CRAL_TRIO_2 PF13716.6 GBG60479.1 - 2.2e-17 63.5 0.2 3.4e-17 62.9 0.2 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GBG60479.1 - 6.5e-05 22.7 0.5 0.00019 21.2 0.4 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain Leu_zip PF15294.6 GBG60480.1 - 0.018 14.6 29.1 0.023 14.2 29.1 1.1 1 0 0 1 1 1 0 Leucine zipper SlyX PF04102.12 GBG60480.1 - 0.79 10.4 18.0 0.24 12.1 4.6 3.2 2 1 1 3 3 3 0 SlyX Exonuc_VII_L PF02601.15 GBG60480.1 - 0.88 9.1 14.6 1.2 8.7 14.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PRKG1_interact PF15898.5 GBG60480.1 - 1.2 10.1 27.6 1.6 9.7 9.2 2.5 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1515 PF07439.11 GBG60480.1 - 2 8.5 9.6 0.19 11.8 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Pox_A_type_inc PF04508.12 GBG60480.1 - 3.7 7.6 10.2 7 6.7 0.0 3.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat COOH-NH2_lig PF14395.6 GBG60480.1 - 4 6.6 7.9 0.59 9.3 1.0 2.0 1 1 1 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 DUF2968 PF11180.8 GBG60480.1 - 4.1 7.0 21.6 0.35 10.5 15.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) AAA_12 PF13087.6 GBG60481.1 - 7.4e-43 146.5 0.0 1.3e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG60481.1 - 1.9e-37 129.5 0.2 2.4e-31 109.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain R3H PF01424.22 GBG60481.1 - 5.6e-10 39.1 0.3 2.5e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 R3H domain AAA_19 PF13245.6 GBG60481.1 - 1.3e-07 32.1 0.0 7.2e-07 29.6 0.0 2.2 3 1 0 3 3 1 1 AAA domain AAA_30 PF13604.6 GBG60481.1 - 1.5e-07 31.4 1.2 5.6e-05 23.0 0.8 3.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG60481.1 - 7.9e-05 23.1 0.4 7.9e-05 23.1 0.4 2.3 2 1 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 GBG60481.1 - 0.00027 20.7 0.0 0.0021 17.9 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 GBG60481.1 - 0.00044 20.5 0.5 0.015 15.6 0.0 3.1 2 1 1 3 3 3 1 AAA domain Helicase_RecD PF05127.14 GBG60481.1 - 0.0063 16.4 0.0 0.87 9.4 0.1 3.2 3 0 0 3 3 3 1 Helicase Viral_helicase1 PF01443.18 GBG60481.1 - 0.011 15.5 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 GBG60481.1 - 0.038 13.2 0.0 0.38 9.9 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase ResIII PF04851.15 GBG60481.1 - 0.087 12.8 0.0 0.28 11.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GBG60481.1 - 0.089 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain cobW PF02492.19 GBG60481.1 - 0.13 11.9 0.0 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 GBG60481.1 - 0.13 12.0 0.0 1.2 8.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 GBG60481.1 - 0.19 11.5 0.0 4.2 7.1 0.0 2.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF2075 PF09848.9 GBG60481.1 - 0.21 10.8 0.1 8.7 5.5 0.0 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 GBG60481.1 - 0.26 11.7 0.8 4 7.9 0.4 2.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Leu_zip PF15294.6 GBG60482.1 - 7.9e-23 81.4 8.1 1e-22 81.0 8.1 1.1 1 0 0 1 1 1 1 Leucine zipper Ribosomal_S3_C PF00189.20 GBG60483.1 - 4.1e-25 88.1 0.3 1.7e-24 86.1 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GBG60483.1 - 8.7e-14 51.1 0.1 1.4e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 GBG60483.1 - 0.027 15.0 0.0 0.055 14.0 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 GBG60483.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus TCP PF03634.13 GBG60484.1 - 7.4e-31 107.8 7.8 3.3e-25 89.5 0.0 3.3 3 0 0 3 3 3 2 TCP family transcription factor DDHD PF02862.17 GBG60484.1 - 0.034 14.3 7.2 0.084 13.0 7.2 1.6 1 0 0 1 1 1 0 DDHD domain EOS1 PF12326.8 GBG60484.1 - 0.04 13.8 0.1 0.069 13.1 0.1 1.4 1 0 0 1 1 1 0 N-glycosylation protein DUF1980 PF09323.10 GBG60484.1 - 0.14 12.1 3.4 0.23 11.4 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SID-1_RNA_chan PF13965.6 GBG60484.1 - 0.22 9.9 0.7 0.29 9.5 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 GBG60484.1 - 0.79 9.7 9.4 1.5 8.8 9.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 GBG60484.1 - 2.2 7.1 5.3 4.3 6.2 5.3 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4770 PF15994.5 GBG60484.1 - 2.9 8.1 23.7 4.8 7.4 23.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SpoIIP PF07454.11 GBG60484.1 - 2.9 7.3 17.1 4.4 6.7 17.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4834 PF16118.5 GBG60484.1 - 3.3 8.7 19.7 12 7.0 19.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Tim54 PF11711.8 GBG60484.1 - 3.8 6.2 16.1 5.5 5.7 16.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BolA PF01722.18 GBG60485.1 - 3.1e-05 24.2 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein Trypan_PARP PF05887.11 GBG60485.1 - 0.0012 18.8 1.4 0.0015 18.5 0.6 1.7 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF3553 PF12073.8 GBG60485.1 - 0.11 12.2 0.4 0.24 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) zf-C3HC4_3 PF13920.6 GBG60487.1 - 1.5e-12 47.1 12.4 3e-12 46.2 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 GBG60487.1 - 3.5e-11 42.3 4.5 0.0011 18.9 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG60487.1 - 4.9e-09 35.6 3.0 0.001 18.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Prok-RING_4 PF14447.6 GBG60487.1 - 1e-06 28.5 9.2 1e-06 28.5 9.2 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 SR-25 PF10500.9 GBG60487.1 - 0.00012 21.8 4.1 0.00012 21.8 4.1 6.7 5 2 2 7 7 5 2 Nuclear RNA-splicing-associated protein zf-C3HC4 PF00097.25 GBG60487.1 - 0.00054 19.8 10.5 0.0011 18.7 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.6 GBG60487.1 - 0.00071 19.8 2.1 0.029 14.7 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG60487.1 - 0.0013 18.4 0.4 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 GBG60487.1 - 0.0038 17.3 1.4 0.068 13.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GBG60487.1 - 0.011 15.9 0.1 0.027 14.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_5 PF14634.6 GBG60487.1 - 0.015 15.3 13.0 0.039 13.9 13.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG60487.1 - 0.72 9.9 6.9 0.85 9.7 5.4 2.0 1 1 0 1 1 1 0 RING-type zinc-finger TPR_7 PF13176.6 GBG60487.1 - 0.91 9.7 2.9 5 7.4 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Nop14 PF04147.12 GBG60489.1 - 4 5.5 37.7 5.9 5.0 37.7 1.3 1 0 0 1 1 1 0 Nop14-like family GLTP PF08718.11 GBG60490.1 - 1.1e-41 142.5 0.0 1.5e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Phage_30_3 PF08010.11 GBG60490.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Dynamitin PF04912.14 GBG60491.1 - 3.7e-38 131.9 13.9 5.6e-38 131.3 11.2 2.0 2 0 0 2 2 2 1 Dynamitin RVT_1 PF00078.27 GBG60491.1 - 1.5e-16 60.6 0.1 2.4e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG60491.1 - 1.9e-07 31.6 0.0 5e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60491.1 - 1.4e-06 28.8 0.0 4.1e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG60491.1 - 6.7e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60491.1 - 0.0009 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease TolA_bind_tri PF16331.5 GBG60491.1 - 0.016 15.3 6.0 6.4 6.9 0.0 4.6 4 1 0 4 4 4 0 TolA binding protein trimerisation NPV_P10 PF05531.12 GBG60491.1 - 0.078 13.5 4.4 6.9 7.2 0.2 3.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CK2S PF15011.6 GBG60491.1 - 0.36 10.7 4.4 0.47 10.3 1.4 2.8 3 0 0 3 3 3 0 Casein Kinase 2 substrate DASH_Dad3 PF08656.10 GBG60491.1 - 7.5 6.7 6.5 28 4.9 0.0 3.9 4 0 0 4 4 4 0 DASH complex subunit Dad3 Glyco_transf_92 PF01697.27 GBG60492.1 - 5.9e-19 68.7 2.4 1.7e-18 67.2 0.1 2.4 2 1 1 3 3 3 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 GBG60492.1 - 7.2e-07 29.6 0.1 1.8e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 CDC45 PF02724.14 GBG60492.1 - 0.096 11.0 2.0 0.15 10.3 2.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Mito_fiss_reg PF05308.11 GBG60492.1 - 2.3 8.2 5.5 0.59 10.2 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator MIP-T3_C PF17749.1 GBG60492.1 - 6.3 6.8 9.4 2.4 8.1 0.1 2.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF2457 PF10446.9 GBG60493.1 - 0.00011 21.5 24.4 0.00011 21.5 24.4 7.3 5 1 2 8 8 8 1 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 GBG60493.1 - 0.0018 18.0 31.1 0.0018 18.0 31.1 6.7 4 1 1 5 5 5 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG60493.1 - 0.0023 17.4 15.8 0.0023 17.4 15.8 4.3 4 1 1 5 5 5 1 SDA1 Csm1_N PF18504.1 GBG60493.1 - 0.68 10.3 9.0 1.8 9.0 1.3 3.7 3 0 0 3 3 3 0 Csm1 N-terminal domain Cnd1 PF12717.7 GBG60494.1 - 1.4e-05 25.2 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GBG60494.1 - 2.3e-05 24.7 0.4 4.7e-05 23.7 0.3 1.6 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.22 GBG60494.1 - 6.6e-05 22.8 0.1 0.63 10.4 0.0 2.9 2 1 0 2 2 2 2 HEAT repeat Adaptin_N PF01602.20 GBG60494.1 - 0.00044 18.9 0.0 0.00053 18.7 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region RTP1_C2 PF10304.9 GBG60494.1 - 0.03 14.0 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_EZ PF13513.6 GBG60494.1 - 0.032 14.8 0.3 0.81 10.3 0.1 2.4 1 1 1 2 2 2 0 HEAT-like repeat UbiA PF01040.18 GBG60495.1 - 4.4e-38 131.0 10.3 6.4e-38 130.5 10.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family FA_desaturase PF00487.24 GBG60495.1 - 0.97 9.2 5.4 0.34 10.7 2.0 1.8 1 1 1 2 2 2 0 Fatty acid desaturase SSF PF00474.17 GBG60497.1 - 2.1e-89 300.2 19.2 2.1e-89 300.2 19.2 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family Dimer_Tnp_hAT PF05699.14 GBG60499.1 - 3.3e-06 26.8 0.0 6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Metalloenzyme PF01676.18 GBG60500.1 - 3.6e-83 278.8 0.0 4.1e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 GBG60500.1 - 5e-59 199.4 0.1 9.6e-59 198.4 0.0 1.5 2 0 0 2 2 2 1 BPG-independent PGAM N-terminus (iPGM_N) PglZ PF08665.12 GBG60500.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 PglZ domain AAA_23 PF13476.6 GBG60501.1 - 0.00097 19.7 7.4 0.0014 19.1 7.4 1.3 1 0 0 1 1 1 1 AAA domain zf-CCHC PF00098.23 GBG60501.1 - 0.04 14.0 0.5 0.074 13.2 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle SOBP PF15279.6 GBG60501.1 - 0.62 10.6 11.0 0.92 10.1 11.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein U79_P34 PF03064.16 GBG60501.1 - 0.86 8.9 16.6 0.26 10.6 13.4 1.9 2 0 0 2 2 2 0 HSV U79 / HCMV P34 ArAE_2_N PF10337.9 GBG60501.1 - 1.6 7.7 5.8 3 6.8 5.8 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 GBG60501.1 - 5.9 5.6 12.7 8.7 5.0 12.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Peroxin-13_N PF04088.13 GBG60501.1 - 9.1 6.5 5.9 18 5.6 5.9 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FapA PF03961.13 GBG60501.1 - 10 4.6 14.6 19 3.7 14.6 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Metalloenzyme PF01676.18 GBG60502.1 - 1.4e-82 276.8 0.0 1.6e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 GBG60502.1 - 7.5e-59 198.8 0.1 1.4e-58 197.9 0.0 1.5 2 0 0 2 2 2 1 BPG-independent PGAM N-terminus (iPGM_N) PglZ PF08665.12 GBG60502.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 PglZ domain CK_II_beta PF01214.18 GBG60503.1 - 2.1e-80 268.8 0.1 2.6e-80 268.5 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RPN2_C PF18004.1 GBG60505.1 - 0.028 14.3 9.4 0.041 13.8 9.4 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 GBG60505.1 - 0.052 13.4 12.5 0.058 13.2 12.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 GBG60505.1 - 0.22 11.9 8.9 0.27 11.7 8.9 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 GBG60505.1 - 0.33 10.1 7.4 0.35 10.0 7.4 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 GBG60505.1 - 0.41 9.0 25.5 0.46 8.9 25.5 1.0 1 0 0 1 1 1 0 Mpp10 protein SpoIIP PF07454.11 GBG60505.1 - 0.45 9.9 9.5 0.49 9.8 9.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CDC27 PF09507.10 GBG60505.1 - 0.63 9.4 17.1 0.75 9.1 17.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CNDH2_C PF16858.5 GBG60505.1 - 0.64 9.8 11.5 0.73 9.7 11.5 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF913 PF06025.12 GBG60505.1 - 0.65 8.9 6.3 0.77 8.7 6.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PSK PF06404.12 GBG60505.1 - 0.69 11.0 13.3 1.1 10.3 13.3 1.4 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) Connexin PF00029.19 GBG60505.1 - 0.71 9.6 4.7 0.85 9.3 4.7 1.2 1 0 0 1 1 1 0 Connexin FGF-BP1 PF06473.12 GBG60505.1 - 0.8 9.5 7.7 0.9 9.3 7.7 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) V_ATPase_I PF01496.19 GBG60505.1 - 0.97 7.3 10.5 1.2 7.0 10.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 GBG60505.1 - 0.98 9.5 3.2 1.1 9.4 3.2 1.1 1 0 0 1 1 1 0 DDHD domain STAC2_u1 PF16664.5 GBG60505.1 - 1 9.8 12.4 1.5 9.3 12.4 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 CCSAP PF15748.5 GBG60505.1 - 1 9.5 13.1 1.2 9.2 13.1 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Vfa1 PF08432.10 GBG60505.1 - 1.5 9.1 13.4 1.9 8.8 13.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4746 PF15928.5 GBG60505.1 - 1.8 7.9 20.1 2.1 7.7 20.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 GBG60505.1 - 1.9 8.2 17.3 2.8 7.7 17.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Trypan_PARP PF05887.11 GBG60505.1 - 2 8.4 21.9 2.4 8.2 21.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Raftlin PF15250.6 GBG60505.1 - 2.1 7.0 9.8 2.3 6.9 9.8 1.0 1 0 0 1 1 1 0 Raftlin RRN3 PF05327.11 GBG60505.1 - 2.3 6.7 15.0 2.5 6.5 15.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pes-10 PF07149.11 GBG60505.1 - 3.1 6.8 26.1 3.9 6.4 26.1 1.0 1 0 0 1 1 1 0 Pes-10 Sec62 PF03839.16 GBG60505.1 - 3.2 7.2 5.0 3.8 6.9 5.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 GBG60505.1 - 3.6 6.3 10.5 3.9 6.2 10.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 GBG60505.1 - 3.9 5.6 30.3 4.3 5.4 30.3 1.0 1 0 0 1 1 1 0 Nop14-like family Usp PF00582.26 GBG60505.1 - 4.2 7.9 8.5 5.6 7.5 8.5 1.2 1 0 0 1 1 1 0 Universal stress protein family SLC12 PF03522.15 GBG60505.1 - 4.3 6.3 6.0 4.8 6.1 6.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIIAH PF12685.7 GBG60505.1 - 4.6 7.0 15.6 5.5 6.8 15.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein CobT PF06213.12 GBG60505.1 - 5.1 6.4 30.5 6 6.2 30.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2722 PF10846.8 GBG60505.1 - 5.2 5.9 10.7 6.5 5.6 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GET2 PF08690.10 GBG60505.1 - 7.1 6.2 9.0 8.3 6.0 9.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 CDC45 PF02724.14 GBG60505.1 - 7.5 4.7 23.3 8.7 4.5 23.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 GBG60505.1 - 8.7 5.2 27.6 9.5 5.1 27.6 1.1 1 0 0 1 1 1 0 Paf1 DUF5523 PF17661.1 GBG60505.1 - 9.2 5.9 22.0 12 5.5 22.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) zf-CCHC_3 PF13917.6 GBG60506.1 - 0.0017 18.3 1.0 0.0038 17.2 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle 2OG-FeII_Oxy_3 PF13640.6 GBG60506.1 - 0.066 14.1 0.0 0.26 12.2 0.0 2.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-CCHC PF00098.23 GBG60506.1 - 2 8.6 4.9 4.2 7.6 4.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Glyco_transf_92 PF01697.27 GBG60507.1 - 5.8e-18 65.5 0.1 1.5e-16 60.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 GBG60507.1 - 2.3e-09 37.7 0.1 4.3e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Dimer_Tnp_hAT PF05699.14 GBG60508.1 - 0.00014 21.6 0.9 0.0003 20.5 0.2 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Arf PF00025.21 GBG60510.1 - 8.3e-22 77.5 0.1 9.2e-22 77.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Nop14 PF04147.12 GBG60511.1 - 0.053 11.7 21.4 0.06 11.6 21.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG60511.1 - 0.065 11.5 19.1 0.083 11.2 19.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG60511.1 - 0.1 12.0 21.1 0.11 11.8 21.1 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG60511.1 - 0.12 11.0 20.7 0.15 10.6 20.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GEMIN8 PF15348.6 GBG60511.1 - 0.13 12.6 13.3 0.15 12.3 13.3 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Cwf_Cwc_15 PF04889.12 GBG60511.1 - 0.34 10.6 18.9 0.47 10.2 18.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Lin-8 PF03353.15 GBG60511.1 - 1.3 8.5 15.8 1.8 8.0 15.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist YL1 PF05764.13 GBG60511.1 - 2.7 8.0 28.2 3.8 7.6 28.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Merozoite_SPAM PF07133.11 GBG60511.1 - 5.9 6.9 31.4 8.6 6.3 31.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) LAP1C PF05609.12 GBG60511.1 - 7 5.6 13.7 9 5.3 13.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 GBG60511.1 - 7.1 5.4 7.7 8 5.2 7.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AIF-MLS PF14962.6 GBG60512.1 - 0.091 12.7 5.7 0.17 11.8 5.7 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF4288 PF14119.6 GBG60512.1 - 0.27 11.7 4.4 0.75 10.2 4.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) DUF572 PF04502.13 GBG60512.1 - 0.44 10.1 10.1 0.54 9.8 10.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) YabA PF06156.13 GBG60512.1 - 4.9 7.8 8.1 10 6.8 0.3 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Vir_act_alpha_C PF10400.9 GBG60512.1 - 6.5 7.5 17.0 1.4e+02 3.2 0.2 3.2 1 1 1 2 2 2 0 Virulence activator alpha C-term ThiS PF02597.20 GBG60514.1 - 3.8e-14 53.1 0.0 4.3e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 ThiS family Herpes_V23 PF01802.17 GBG60514.1 - 0.071 12.5 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 Herpesvirus VP23 like capsid protein CDC45 PF02724.14 GBG60515.1 - 0.061 11.6 18.8 0.073 11.4 18.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG60515.1 - 0.13 11.6 28.3 0.17 11.2 28.3 1.1 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 GBG60515.1 - 0.28 10.2 11.0 0.35 9.9 11.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PPP4R2 PF09184.11 GBG60515.1 - 0.99 8.9 20.4 1.6 8.2 20.4 1.4 1 0 0 1 1 1 0 PPP4R2 SURF2 PF05477.11 GBG60515.1 - 1.1 8.9 18.2 1.6 8.4 18.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 GBG60515.1 - 4.2 5.5 29.4 5 5.2 29.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG60515.1 - 4.4 6.5 28.7 5.7 6.2 28.7 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 GBG60515.1 - 9.5 5.4 21.3 18 4.6 21.3 1.5 1 0 0 1 1 1 0 NOA36 protein rve PF00665.26 GBG60516.1 - 0.0001 22.5 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain AAA_33 PF13671.6 GBG60517.1 - 0.00034 20.8 0.0 0.00085 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 GBG60517.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 GBG60517.1 - 0.17 12.4 0.2 0.74 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GBG60518.1 - 0.0003 21.0 0.0 0.00077 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 GBG60518.1 - 0.056 12.9 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 GBG60518.1 - 0.14 12.7 0.2 0.68 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 GBG60519.1 - 2.5e-61 207.4 0.0 2.5e-61 207.4 0.0 2.0 2 0 0 2 2 1 1 Protein kinase domain RVT_1 PF00078.27 GBG60519.1 - 3.3e-34 118.3 0.1 6.4e-34 117.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG60519.1 - 1.2e-31 110.0 0.0 2.7e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RT_RNaseH_2 PF17919.1 GBG60519.1 - 1e-29 102.5 0.0 3.2e-29 100.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60519.1 - 1e-28 99.7 0.0 3.1e-28 98.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Kinase-like PF14531.6 GBG60519.1 - 0.00033 20.1 0.0 0.00097 18.5 0.0 1.8 1 0 0 1 1 1 1 Kinase-like RVP_2 PF08284.11 GBG60519.1 - 0.0004 20.2 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60519.1 - 0.016 15.9 0.0 0.04 14.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease APH PF01636.23 GBG60519.1 - 0.017 15.0 0.2 0.11 12.4 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GBG60519.1 - 0.15 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 TadF PF16964.5 GBG60519.1 - 0.18 11.5 3.0 0.47 10.2 3.0 1.7 1 0 0 1 1 1 0 Putative tight adherence pilin protein F PAP2 PF01569.21 GBG60520.1 - 7.7e-30 103.4 2.9 7.7e-30 103.4 2.9 1.9 2 0 0 2 2 2 1 PAP2 superfamily Virul_fac_BrkB PF03631.15 GBG60520.1 - 0.00059 19.5 0.5 0.00059 19.5 0.5 2.1 2 0 0 2 2 2 1 Virulence factor BrkB PAP2_3 PF14378.6 GBG60520.1 - 0.0018 18.0 12.5 0.0019 17.9 9.3 2.5 1 1 1 2 2 2 1 PAP2 superfamily DUF3087 PF11286.8 GBG60520.1 - 0.14 11.7 0.9 0.29 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) RNA_pol_3_Rpc31 PF11705.8 GBG60522.1 - 4.9 7.3 12.7 12 6.1 12.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sugar_tr PF00083.24 GBG60523.1 - 3.9e-98 329.3 16.0 5.8e-98 328.7 16.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GBG60523.1 - 4.3e-29 101.5 25.5 4.3e-29 101.5 25.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily RVT_1 PF00078.27 GBG60523.1 - 3.4e-26 92.1 0.0 5.9e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRI12 PF06609.13 GBG60523.1 - 9.3e-08 30.9 2.6 9.3e-08 30.9 2.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Asp_protease_2 PF13650.6 GBG60523.1 - 1.2e-05 25.9 0.0 2.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60523.1 - 2.8e-05 24.6 0.0 8.4e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60523.1 - 0.00029 20.6 0.0 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG60523.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Use1 PF09753.9 GBG60523.1 - 0.79 9.4 14.3 0.87 9.3 11.9 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 FAM91_N PF14647.6 GBG60524.1 - 2.2e-94 316.2 0.4 3.1e-94 315.8 0.4 1.1 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.6 GBG60524.1 - 2e-73 247.7 0.0 4.9e-44 150.8 0.0 3.3 2 1 0 2 2 2 2 FAM91 C-terminus HTH_9 PF08221.11 GBG60525.1 - 2.4e-20 72.4 1.3 5.1e-15 55.3 0.1 2.5 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 GBG60525.1 - 8.1e-05 22.4 0.1 0.0054 16.6 0.0 2.1 2 0 0 2 2 2 2 TFIIE alpha subunit HTH_AsnC-type PF13404.6 GBG60525.1 - 0.038 13.8 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 GBG60526.1 - 2.2e-15 57.1 0.2 5.6e-15 55.8 0.2 1.6 1 1 0 1 1 1 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 GBG60526.1 - 0.007 16.2 2.5 0.032 14.1 0.4 2.5 2 1 1 3 3 3 1 TFIIE alpha subunit TrmB PF01978.19 GBG60526.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_9 PF08221.11 GBG60526.1 - 0.037 14.1 0.5 1.5 9.0 0.1 2.6 2 1 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF1564 PF07600.11 GBG60526.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG60527.1 - 1.4e-06 28.0 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60528.1 - 8.4e-26 89.9 0.0 2.5e-25 88.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60528.1 - 2.6e-21 75.9 0.0 9.2e-21 74.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60528.1 - 2.4e-18 66.0 0.3 9.5e-18 64.1 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG60528.1 - 8.7e-06 26.2 0.0 2.7e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60528.1 - 2.1e-05 25.1 0.0 6.5e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60528.1 - 2.5e-05 24.1 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG60528.1 - 0.0032 17.7 3.2 0.014 15.7 0.0 3.4 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG60528.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Chromo PF00385.24 GBG60528.1 - 0.095 12.6 0.1 0.27 11.2 0.1 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG60528.1 - 0.096 12.9 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger TMF_TATA_bd PF12325.8 GBG60529.1 - 0.019 15.2 3.0 0.019 15.2 3.0 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 GBG60529.1 - 0.032 13.5 0.9 0.032 13.5 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 GBG60529.1 - 0.047 14.2 2.7 6.9 7.2 0.2 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 GBG60529.1 - 0.11 12.5 2.0 11 6.1 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2781 PF10914.8 GBG60529.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) FAM76 PF16046.5 GBG60529.1 - 0.66 9.3 7.1 0.84 8.9 6.5 1.4 1 1 0 1 1 1 0 FAM76 protein AIF-MLS PF14962.6 GBG60529.1 - 3.7 7.5 9.3 0.91 9.5 5.1 1.8 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Fib_alpha PF08702.10 GBG60529.1 - 4.4 7.5 7.1 2.6 8.2 1.8 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 GBG60529.1 - 4.6 6.5 21.1 3.1 7.1 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Use1 PF09753.9 GBG60529.1 - 8.1 6.1 11.5 8.5 6.0 10.6 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 RVT_1 PF00078.27 GBG60530.1 - 3.3e-30 105.3 0.1 1.1e-19 70.8 0.0 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60530.1 - 6.2e-14 52.2 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG60530.1 - 2.7e-09 37.0 0.5 5.5e-09 36.0 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG60531.1 - 5.9e-16 58.3 0.0 1.4e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60531.1 - 2e-14 53.7 0.0 9.2e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60531.1 - 4.7e-07 30.3 0.3 1.4e-06 28.8 0.1 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60531.1 - 1.2e-05 25.9 0.4 2.9e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG60531.1 - 0.00067 19.4 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60531.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Ferlin_C PF16165.5 GBG60532.1 - 0.3 11.0 0.8 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Ferlin C-terminus Nop14 PF04147.12 GBG60532.1 - 2.7 6.1 16.3 3.4 5.8 16.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF659 PF04937.15 GBG60533.1 - 2e-12 47.3 0.0 3.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG60534.1 - 2.5e-26 91.6 0.0 1e-25 89.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60534.1 - 1e-23 83.6 0.0 3.4e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60534.1 - 7.3e-21 74.7 0.1 1.6e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ZapB PF06005.12 GBG60534.1 - 0.0044 17.4 1.0 0.018 15.5 0.1 2.6 2 0 0 2 2 2 1 Cell division protein ZapB RVP_2 PF08284.11 GBG60534.1 - 0.0099 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG60534.1 - 0.028 14.7 4.7 0.047 14.0 2.4 2.6 2 1 0 2 2 2 0 Retrotransposon gag protein rve PF00665.26 GBG60534.1 - 0.095 12.9 0.1 0.37 11.0 0.1 2.0 1 0 0 1 1 1 0 Integrase core domain Integrase_H2C2 PF17921.1 GBG60535.1 - 1.4e-17 63.5 1.9 1.4e-16 60.3 1.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG60535.1 - 3.5e-08 33.7 0.0 6.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG60535.1 - 0.051 13.8 0.8 0.1 12.9 0.8 1.5 1 0 0 1 1 1 0 H2C2 zinc finger LRR_8 PF13855.6 GBG60536.1 - 7.2e-11 41.7 11.5 2.6e-08 33.5 2.8 2.7 2 0 0 2 2 2 2 Leucine rich repeat Asp_protease_2 PF13650.6 GBG60536.1 - 1.1e-07 32.4 0.0 9.5e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60536.1 - 1.9e-07 31.6 0.0 1.9e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG60536.1 - 3.9e-07 29.9 0.0 7.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease LRR_4 PF12799.7 GBG60536.1 - 4.5e-07 30.1 10.3 2.6e-05 24.5 4.2 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Asp_protease PF09668.10 GBG60536.1 - 2.6e-05 24.0 0.0 4.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease LRR_1 PF00560.33 GBG60536.1 - 0.00088 19.5 4.8 0.32 11.7 0.7 4.3 3 0 0 3 3 3 1 Leucine Rich Repeat RXLR PF16810.5 GBG60536.1 - 0.066 13.7 3.5 0.15 12.5 3.5 1.7 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity TFIIA PF03153.13 GBG60536.1 - 1 9.3 12.3 1.7 8.5 12.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMF_DNA_bd PF12329.8 GBG60536.1 - 5.4 7.1 11.8 0.46 10.5 0.3 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RT_RNaseH PF17917.1 GBG60537.1 - 1.3e-20 73.6 0.0 2.4e-19 69.6 0.0 3.0 4 0 0 4 4 4 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60537.1 - 5.4e-20 71.3 0.0 2.7e-19 69.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG60537.1 - 0.011 16.0 0.9 0.047 14.0 0.1 2.5 2 1 1 3 3 3 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG60538.1 - 5.1e-26 91.6 0.0 8.3e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60538.1 - 1.8e-09 37.8 0.0 8.5e-09 35.6 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain DUF4399 PF14347.6 GBG60538.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Abhydrolase_1 PF00561.20 GBG60540.1 - 1.1e-33 117.0 0.0 1.4e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG60540.1 - 1.2e-12 47.6 0.0 1.8e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG60540.1 - 6.5e-10 40.0 0.1 9.9e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 GBG60540.1 - 0.0021 17.7 0.2 0.0062 16.2 0.2 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.14 GBG60540.1 - 0.0082 14.9 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 GBG60540.1 - 0.0089 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S10 PF00450.22 GBG60540.1 - 0.04 13.3 0.6 2.1 7.7 0.6 2.3 2 0 0 2 2 2 0 Serine carboxypeptidase Esterase PF00756.20 GBG60540.1 - 0.062 12.9 0.1 0.98 9.0 0.0 2.1 1 1 1 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 GBG60540.1 - 0.086 12.3 0.0 0.52 9.8 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 GBG60540.1 - 0.13 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 RT_RNaseH_2 PF17919.1 GBG60541.1 - 3.7e-17 62.2 0.0 7.7e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60541.1 - 7.2e-10 38.8 0.1 1.6e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG60541.1 - 4.1e-06 27.0 0.0 1.2e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG60541.1 - 0.00029 21.4 0.0 0.00064 20.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60541.1 - 0.001 19.6 0.0 0.0022 18.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG60541.1 - 0.022 14.8 1.9 0.041 14.0 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 GBG60542.1 - 2.3e-38 132.1 0.0 6.7e-38 130.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG60542.1 - 5.2e-36 124.3 0.0 9.6e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 GBG60542.1 - 9e-09 35.2 0.2 2.4e-08 33.8 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.23 GBG60542.1 - 2.6e-05 24.3 0.0 2.6e-05 24.3 0.0 3.4 2 2 2 4 4 4 1 Phosphotransferase enzyme family Retrotrans_gag PF03732.17 GBG60542.1 - 0.00042 20.5 1.1 0.0071 16.6 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein PRIMA1 PF16101.5 GBG60542.1 - 0.0044 17.1 2.0 0.011 15.8 2.0 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Pkinase_fungal PF17667.1 GBG60542.1 - 0.058 12.2 0.0 0.16 10.7 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase Baculo_PEP_C PF04513.12 GBG60542.1 - 0.29 11.2 1.2 0.64 10.1 1.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NHL PF01436.21 GBG60542.1 - 0.31 11.2 4.3 3.8 7.7 0.4 3.5 3 0 0 3 3 3 0 NHL repeat DUF659 PF04937.15 GBG60543.1 - 7.5e-19 68.1 0.0 1.7e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ExsD PF16806.5 GBG60543.1 - 0.042 13.8 6.4 0.084 12.8 6.4 1.4 1 0 0 1 1 1 0 Antiactivator protein ExsD DUF2722 PF10846.8 GBG60543.1 - 0.13 11.2 5.0 0.18 10.7 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 GBG60543.1 - 0.54 8.5 15.6 0.74 8.0 15.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 GBG60543.1 - 5.3 6.3 21.3 7.4 5.8 21.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pkinase PF00069.25 GBG60544.1 - 7.4e-38 130.4 0.0 1.2e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG60544.1 - 5.6e-35 120.9 0.0 1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG60544.1 - 3.9e-06 27.0 0.0 8.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GBG60544.1 - 0.014 14.8 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rax2 PF12768.7 GBG60544.1 - 0.025 14.0 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Pkinase_fungal PF17667.1 GBG60544.1 - 0.026 13.3 0.0 0.069 11.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase NHL PF01436.21 GBG60544.1 - 0.05 13.7 1.5 6.3 7.0 0.1 3.7 4 0 0 4 4 4 0 NHL repeat NB PF04159.13 GBG60544.1 - 0.071 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 NB glycoprotein tRNA_int_endo PF01974.17 GBG60544.1 - 0.16 12.1 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain RNase_PH PF01138.21 GBG60545.1 - 2.6e-18 66.8 0.0 5.1e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GBG60545.1 - 1.2e-13 50.8 0.0 2.8e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SDA1 PF05285.12 GBG60545.1 - 0.013 15.0 17.3 0.023 14.2 17.3 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG60545.1 - 0.013 13.8 10.7 0.019 13.3 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GBG60545.1 - 0.022 13.3 14.5 0.031 12.7 14.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG60545.1 - 0.038 12.2 17.7 0.056 11.7 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG60545.1 - 0.058 12.2 0.1 0.075 11.8 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 GBG60545.1 - 0.16 11.1 0.2 0.23 10.6 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SGT1 PF07093.11 GBG60545.1 - 1.2 7.5 9.2 1.7 7.0 9.2 1.1 1 0 0 1 1 1 0 SGT1 protein RNA_pol_Rpc4 PF05132.14 GBG60545.1 - 1.4 9.3 7.5 0.99 9.8 5.2 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 BUD22 PF09073.10 GBG60545.1 - 1.8 7.9 16.6 0.33 10.3 13.1 1.5 2 0 0 2 2 2 0 BUD22 RR_TM4-6 PF06459.12 GBG60545.1 - 1.8 8.3 11.0 3.6 7.3 11.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SURF2 PF05477.11 GBG60545.1 - 3.5 7.2 12.2 6.6 6.4 12.2 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Paf1 PF03985.13 GBG60545.1 - 4.5 6.2 18.0 7.7 5.4 18.0 1.3 1 0 0 1 1 1 0 Paf1 DUF2722 PF10846.8 GBG60545.1 - 7.1 5.4 7.3 11 4.8 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Integrase_H2C2 PF17921.1 GBG60546.1 - 4.4e-15 55.5 0.3 1.2e-14 54.1 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG60546.1 - 2.4e-06 27.7 0.0 5.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG60546.1 - 3.5e-05 24.3 0.0 9.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60546.1 - 0.0068 17.0 0.0 0.021 15.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG60546.1 - 0.011 15.9 0.8 0.048 13.9 0.8 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG60546.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF4045 PF13254.6 GBG60546.1 - 0.47 10.1 15.3 0.82 9.2 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 GBG60546.1 - 6.1 5.5 11.1 11 4.6 11.1 1.4 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 GBG60547.1 - 5.2e-17 61.9 10.5 0.0012 19.7 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG60547.1 - 1e-05 25.8 1.4 0.0061 16.8 0.3 4.2 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG60547.1 - 0.00033 19.4 2.3 0.056 12.1 0.6 2.4 1 1 0 2 2 2 2 Nucleoporin Nup120/160 DDE_Tnp_4 PF13359.6 GBG60548.1 - 1e-16 61.0 0.0 2.1e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60548.1 - 3.4e-05 23.6 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Protoglobin PF11563.8 GBG60549.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Protoglobin MAJIN PF15077.6 GBG60550.1 - 2.7 7.7 7.1 3.7 7.3 7.1 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein RR_TM4-6 PF06459.12 GBG60550.1 - 8.6 6.1 7.6 9.7 5.9 7.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GDP_Man_Dehyd PF16363.5 GBG60551.1 - 2.6e-43 148.7 0.0 1.1e-42 146.6 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG60551.1 - 1.8e-34 119.3 0.0 2.3e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GBG60551.1 - 2.3e-07 30.3 0.0 0.002 17.3 0.0 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GBG60551.1 - 2.5e-07 30.1 0.0 3.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 GBG60551.1 - 5.1e-05 22.5 0.0 6.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 GBG60551.1 - 0.00068 18.7 0.0 0.0009 18.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Myb_DNA-binding PF00249.31 GBG60552.1 - 3.5e-24 84.7 0.6 1.1e-10 41.5 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG60552.1 - 4.7e-16 58.8 1.2 1.1e-08 35.2 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain AAA_23 PF13476.6 GBG60552.1 - 0.13 12.7 5.5 0.15 12.5 0.7 2.3 2 0 0 2 2 2 0 AAA domain BSP_II PF05432.11 GBG60552.1 - 0.2 11.3 5.9 0.12 12.1 1.2 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF2828 PF11443.8 GBG60552.1 - 0.65 8.0 6.5 1.3 7.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 GBG60552.1 - 1.4 7.6 15.2 2.5 6.8 3.1 2.2 2 0 0 2 2 2 0 Presenilin Spt5_N PF11942.8 GBG60552.1 - 5.1 8.1 26.4 0.36 11.8 12.7 2.9 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Pet20 PF08692.10 GBG60552.1 - 7 7.4 5.8 12 6.6 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial protein Pet20 DUF659 PF04937.15 GBG60553.1 - 0.23 11.3 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Oxysterol_BP PF01237.18 GBG60555.1 - 5.1e-101 338.2 0.0 6.8e-101 337.8 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Sas10_Utp3 PF04000.15 GBG60556.1 - 4.2e-05 24.1 0.6 9e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF773 PF05600.12 GBG60556.1 - 0.021 13.6 0.3 0.033 12.9 0.3 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Metal_resist PF13801.6 GBG60556.1 - 0.024 14.9 0.9 0.024 14.9 0.9 2.1 2 0 0 2 2 2 0 Heavy-metal resistance AAA_11 PF13086.6 GBG60556.1 - 0.23 11.2 2.7 0.3 10.8 2.7 1.2 1 0 0 1 1 1 0 AAA domain DDRGK PF09756.9 GBG60556.1 - 1.7 8.2 10.5 3.5 7.2 10.5 1.5 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 GBG60556.1 - 2.4 7.9 6.9 3.3 7.5 6.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PRA1 PF03208.19 GBG60557.1 - 1e-35 122.5 6.7 1.3e-35 122.1 6.7 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF4191 PF13829.6 GBG60557.1 - 0.083 12.2 2.7 1.2 8.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF4870 PF09685.10 GBG60557.1 - 0.16 12.1 6.2 4.2 7.5 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) ABC2_membrane_3 PF12698.7 GBG60557.1 - 0.35 9.9 10.3 0.51 9.4 10.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1189 PF06691.11 GBG60557.1 - 0.73 9.4 4.1 4 6.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) CPBP PF02517.16 GBG60557.1 - 0.78 10.1 6.0 0.29 11.5 0.8 2.1 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease Histone PF00125.24 GBG60558.1 - 4.4e-21 75.6 0.9 4.4e-21 75.6 0.9 2.4 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 DUF1179 PF06678.11 GBG60558.1 - 0.76 9.8 2.2 1.6 8.8 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) FeS_assembly_P PF01883.19 GBG60559.1 - 1.7e-10 40.9 0.0 3.5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein FeS_assembly_P PF01883.19 GBG60560.1 - 5.4e-11 42.5 0.1 9.8e-11 41.7 0.0 1.5 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein DUF3341 PF11821.8 GBG60560.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Retrotrans_gag PF03732.17 GBG60561.1 - 0.0015 18.7 0.2 0.0015 18.7 0.2 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein Proteasome PF00227.26 GBG60562.1 - 1.4e-44 151.9 0.0 1.6e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Clat_adaptor_s PF01217.20 GBG60563.1 - 3.8e-12 46.3 0.1 4.4e-12 46.1 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CRM1_C PF08767.11 GBG60564.1 - 0.00014 21.2 0.0 0.00027 20.2 0.0 1.4 1 0 0 1 1 1 1 CRM1 C terminal IBN_N PF03810.19 GBG60564.1 - 0.00081 19.3 1.0 0.0025 17.7 1.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF917 PF06032.12 GBG60564.1 - 0.034 13.0 0.6 1 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF917) DUF2063 PF09836.9 GBG60564.1 - 0.044 14.0 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 Putative DNA-binding domain DOMON PF03351.17 GBG60565.1 - 3e-10 40.4 0.0 7.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 DOMON domain DBINO PF13892.6 GBG60565.1 - 6.3e-05 23.3 7.3 0.00011 22.6 7.3 1.3 1 0 0 1 1 1 1 DNA-binding domain Cytochrom_B561 PF03188.16 GBG60565.1 - 0.081 13.1 6.8 0.061 13.4 4.2 1.9 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 ATP-synt_ab PF00006.25 GBG60567.1 - 6.2e-105 349.5 0.0 9.2e-105 349.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 GBG60567.1 - 1.5e-44 150.7 0.0 2.7e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 GBG60567.1 - 9e-14 51.8 0.9 2.5e-13 50.3 0.9 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain GFO_IDH_MocA PF01408.22 GBG60568.1 - 3.3e-15 57.0 0.4 6.7e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GBG60568.1 - 1.6e-05 24.9 0.0 0.00052 20.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain K_channel_TID PF07941.11 GBG60568.1 - 0.012 16.0 8.4 0.03 14.8 8.4 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Cellulose_synt PF03552.14 GBG60569.1 - 3e-53 181.4 1.2 4e-53 181.0 1.2 1.0 1 0 0 1 1 1 1 Cellulose synthase DUF3413 PF11893.8 GBG60569.1 - 0.0053 16.0 0.0 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3413) DUF368 PF04018.13 GBG60569.1 - 0.011 15.3 0.2 0.013 15.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF368) RDD PF06271.12 GBG60569.1 - 0.046 13.9 0.6 1.3 9.3 0.6 2.1 1 1 0 1 1 1 0 RDD family CDC45 PF02724.14 GBG60569.1 - 4.4 5.5 5.6 5.7 5.1 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Cellulose_synt PF03552.14 GBG60570.1 - 2.6e-190 634.5 6.7 1e-99 335.0 0.1 2.8 1 1 1 2 2 2 2 Cellulose synthase zf-UDP PF14569.6 GBG60570.1 - 8.6e-20 70.6 7.6 8.6e-20 70.6 7.6 2.3 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 GBG60570.1 - 1.5e-10 40.7 11.9 4.8e-10 39.1 11.9 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Glyco_trans_2_3 PF13632.6 GBG60570.1 - 1.6e-06 28.2 0.7 3.2e-06 27.2 0.7 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 CDC45 PF02724.14 GBG60570.1 - 1 7.6 2.9 1.5 7.0 2.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SGT1 PF07093.11 GBG60570.1 - 3 6.2 5.8 4.7 5.5 5.8 1.2 1 0 0 1 1 1 0 SGT1 protein CobT PF06213.12 GBG60570.1 - 7.3 5.9 10.2 0.099 12.0 3.0 1.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Pep_deformylase PF01327.21 GBG60572.1 - 1e-48 165.0 0.0 1.2e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Prefoldin_2 PF01920.20 GBG60573.1 - 1.4e-16 60.4 8.6 1.5e-16 60.2 8.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit PCRF PF03462.18 GBG60573.1 - 0.0025 17.7 1.7 0.0033 17.3 1.7 1.2 1 0 0 1 1 1 1 PCRF domain Sod_Ni PF09055.11 GBG60573.1 - 0.0027 18.2 0.7 1 9.9 0.2 2.1 1 1 1 2 2 2 2 Nickel-containing superoxide dismutase V_ATPase_I PF01496.19 GBG60573.1 - 0.12 10.3 1.5 0.13 10.1 1.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAGH_C PF16123.5 GBG60573.1 - 0.14 12.7 1.7 4.7 7.8 0.1 2.2 1 1 1 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus DUF2617 PF10936.8 GBG60573.1 - 0.15 12.1 0.5 0.52 10.4 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function DUF2617 FIN1 PF17300.2 GBG60573.1 - 0.61 9.5 5.4 0.73 9.3 5.4 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 YabA PF06156.13 GBG60573.1 - 0.74 10.5 7.4 1.6 9.4 4.7 2.0 1 1 1 2 2 2 0 Initiation control protein YabA YojJ PF10372.9 GBG60573.1 - 5.5 7.2 8.1 4.5 7.4 2.7 2.3 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF2252 PF10009.9 GBG60574.1 - 8.3e-68 229.2 0.0 1.7e-66 224.9 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) Myb_DNA-bind_4 PF13837.6 GBG60576.1 - 0.0014 18.9 0.3 0.0078 16.6 0.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG60577.1 - 2.6e-31 108.5 0.0 8e-31 106.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60577.1 - 1.6e-16 60.5 0.0 2.3e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG60577.1 - 0.04 13.5 0.2 3.2 7.3 0.0 2.3 2 1 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG60577.1 - 0.062 13.7 1.0 0.082 13.3 0.0 1.7 2 0 0 2 2 2 0 Transposase DDE domain Ribosomal_L34 PF00468.17 GBG60578.1 - 4.6e-21 74.5 8.2 1e-20 73.4 8.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L34 GCP_C_terminal PF04130.13 GBG60579.1 - 7.9e-31 107.7 9.4 9.1e-31 107.5 9.4 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal HEPN-like_int PF18867.1 GBG60579.1 - 0.021 14.7 0.2 0.036 13.9 0.2 1.3 1 0 0 1 1 1 0 HEPN-like integron domain GCP_N_terminal PF17681.1 GBG60581.1 - 1.2e-43 149.9 0.0 5.5e-43 147.7 0.0 1.9 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GBG60581.1 - 9e-05 22.1 0.1 0.00015 21.4 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Presenilin PF01080.17 GBG60581.1 - 3.2 6.4 4.1 4.4 6.0 4.1 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GBG60581.1 - 4 7.2 7.4 6.2 6.6 7.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVT_1 PF00078.27 GBG60582.1 - 7.2e-35 120.5 0.0 1.2e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG60582.1 - 0.0045 17.7 8.5 0.0045 17.7 8.5 3.0 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase P53_TAD PF08563.11 GBG60582.1 - 0.66 9.5 5.0 0.093 12.2 0.4 2.1 2 0 0 2 2 2 0 P53 transactivation motif HTH_Tnp_Mu_1 PF02316.16 GBG60582.1 - 2.5 8.3 4.9 2.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Mu DNA-binding domain ADIP PF11559.8 GBG60583.1 - 0.00014 22.0 5.9 0.00018 21.6 5.9 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ZapB PF06005.12 GBG60583.1 - 0.00056 20.3 17.0 0.00072 19.9 8.3 2.2 1 1 1 2 2 2 1 Cell division protein ZapB PSY3 PF16836.5 GBG60583.1 - 0.018 14.5 0.3 0.021 14.4 0.3 1.0 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description DUF4527 PF15030.6 GBG60583.1 - 0.04 13.4 1.7 0.044 13.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) DUF2443 PF10398.9 GBG60583.1 - 0.052 13.6 1.4 0.052 13.6 1.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2443) PRKG1_interact PF15898.5 GBG60583.1 - 0.11 13.4 12.2 0.75 10.7 12.2 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 GBG60583.1 - 0.12 13.0 12.2 0.45 11.0 12.2 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Cas6b_C PF17262.2 GBG60583.1 - 0.13 12.4 3.9 0.16 12.1 3.9 1.2 1 0 0 1 1 1 0 Cas6b C-terminal domain DUF787 PF05619.11 GBG60583.1 - 0.17 11.0 4.4 0.24 10.5 4.4 1.3 1 1 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) TMF_TATA_bd PF12325.8 GBG60583.1 - 0.2 11.9 11.2 0.35 11.1 3.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 GBG60583.1 - 0.21 11.4 14.6 1.3 8.8 6.4 2.5 1 1 1 2 2 2 0 Septum formation initiator CtIP_N PF10482.9 GBG60583.1 - 0.21 11.7 10.6 0.044 13.8 4.2 2.0 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TMF_DNA_bd PF12329.8 GBG60583.1 - 0.33 11.0 16.8 0.94 9.5 1.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.18 GBG60583.1 - 0.52 10.6 12.1 0.15 12.3 2.7 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper BST2 PF16716.5 GBG60583.1 - 0.72 10.5 12.5 1.4 9.5 5.6 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 FAM76 PF16046.5 GBG60583.1 - 0.8 9.0 6.7 0.92 8.8 6.7 1.1 1 0 0 1 1 1 0 FAM76 protein TSC22 PF01166.18 GBG60583.1 - 1.3 9.4 10.9 2.5 8.5 4.3 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.15 GBG60583.1 - 1.4 9.1 13.4 4 7.6 0.8 3.1 2 1 0 2 2 2 0 Basic region leucine zipper YabA PF06156.13 GBG60583.1 - 2.5 8.8 9.3 19 6.0 9.3 2.0 1 1 0 1 1 1 0 Initiation control protein YabA Histone PF00125.24 GBG60584.1 - 2.4e-13 50.6 0.1 4.6e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG60584.1 - 0.093 13.0 0.2 0.093 13.0 0.2 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Period_C PF12114.8 GBG60584.1 - 0.74 9.4 2.9 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Histone PF00125.24 GBG60585.1 - 2.3e-13 50.7 0.1 4.3e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG60585.1 - 0.09 13.1 0.2 0.09 13.1 0.2 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Period_C PF12114.8 GBG60585.1 - 0.7 9.5 2.9 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Phage_integrase PF00589.22 GBG60586.1 - 3.2e-05 23.8 0.0 4.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.27 GBG60587.1 - 1.2e-26 93.7 0.0 1.7e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60587.1 - 8.5e-26 89.9 0.0 1.4e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60587.1 - 1.3e-24 86.5 0.0 2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60588.1 - 2.7e-08 33.8 0.1 4.2e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG60588.1 - 0.0011 19.1 0.1 0.0019 18.3 0.1 1.4 1 0 0 1 1 1 1 H2C2 zinc finger 2-Hacid_dh_C PF02826.19 GBG60589.1 - 1.3e-60 203.8 0.0 2.2e-60 203.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GBG60589.1 - 4.4e-35 120.3 0.4 7.9e-35 119.4 0.4 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 GBG60589.1 - 8e-06 25.5 0.0 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 GBG60589.1 - 3.9e-05 23.8 0.1 9.1e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 GBG60589.1 - 0.005 17.0 2.2 0.0077 16.4 0.2 2.3 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 GBG60589.1 - 0.037 14.5 0.1 0.12 12.9 0.1 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain RRM_1 PF00076.22 GBG60590.1 - 2.1e-09 37.1 0.0 2e-06 27.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG60590.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Retrotrans_gag PF03732.17 GBG60591.1 - 0.034 14.4 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4746 PF15928.5 GBG60591.1 - 0.22 10.9 8.6 0.35 10.3 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Lin-8 PF03353.15 GBG60591.1 - 1.8 8.1 8.5 2.7 7.5 8.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 GBG60591.1 - 3 6.0 11.3 3.9 5.7 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG60591.1 - 3 5.9 18.7 3.9 5.6 18.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG60591.1 - 3.7 6.9 20.7 5.1 6.4 20.7 1.1 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 GBG60591.1 - 6.2 5.8 8.9 7.9 5.4 8.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 GBG60591.1 - 6.4 6.0 17.9 8.6 5.6 17.9 1.1 1 0 0 1 1 1 0 BUD22 Methyltransf_29 PF03141.16 GBG60592.1 - 5.6e-191 635.5 0.0 8.3e-191 634.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 GBG60592.1 - 6e-11 42.9 0.0 1.8e-07 31.7 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 GBG60592.1 - 1.4e-07 32.2 0.0 9.1e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GBG60592.1 - 4.5e-05 23.3 0.0 0.21 11.4 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GBG60592.1 - 0.00011 22.9 0.0 0.1 13.4 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GBG60592.1 - 0.00026 20.9 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MULE PF10551.9 GBG60593.1 - 1.5e-20 73.4 0.0 5.3e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG60593.1 - 1.5e-13 50.5 0.1 3.6e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.18 GBG60593.1 - 2.2e-09 36.6 0.0 3.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family DUF5600 PF18150.1 GBG60595.1 - 3.8e-36 123.9 0.7 9.1e-36 122.7 0.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 GBG60595.1 - 1.4e-14 54.5 0.0 1.1e-12 48.3 0.0 2.5 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 GBG60595.1 - 4.8e-14 51.9 0.1 1.1e-13 50.8 0.1 1.7 1 0 0 1 1 1 1 N-terminal EH-domain containing protein EF-hand_4 PF12763.7 GBG60595.1 - 1.2e-08 34.8 0.0 4e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.23 GBG60595.1 - 8.1e-08 32.4 0.0 2.3e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_7 PF13499.6 GBG60595.1 - 0.0013 19.1 0.0 0.0047 17.4 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair GTP_EFTU PF00009.27 GBG60595.1 - 0.0093 15.5 0.0 0.027 14.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 GBG60595.1 - 0.025 14.8 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Med21 PF11221.8 GBG60595.1 - 0.12 12.7 0.1 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 Subunit 21 of Mediator complex ABC_tran_CTD PF16326.5 GBG60595.1 - 0.13 12.5 0.8 2.4 8.5 0.1 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain EF-hand_1 PF00036.32 GBG60595.1 - 0.14 11.7 0.1 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 EF hand AAA_28 PF13521.6 GBG60595.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Casc1_N PF15927.5 GBG60596.1 - 0.0004 20.2 12.8 0.00077 19.2 12.8 1.5 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus CHD5 PF04420.14 GBG60596.1 - 0.16 11.8 1.9 0.27 11.1 1.9 1.4 1 0 0 1 1 1 0 CHD5-like protein DUF1997 PF09366.10 GBG60597.1 - 4.5e-35 121.1 0.0 5.7e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) Pkinase_Tyr PF07714.17 GBG60598.1 - 8.9e-43 146.4 0.1 2.6e-39 135.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG60598.1 - 5.6e-32 111.1 0.0 4.8e-31 108.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain LysM PF01476.20 GBG60598.1 - 7.2e-11 42.0 0.0 0.0008 19.4 0.0 3.7 3 0 0 3 3 3 3 LysM domain Amnionless PF14828.6 GBG60598.1 - 0.021 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 GBG60598.1 - 1.2 9.0 7.2 2.2 8.1 7.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 gpW PF02831.15 GBG60600.1 - 0.048 13.6 0.0 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 gpW MNNL PF07657.13 GBG60600.1 - 0.29 11.2 2.4 0.81 9.8 2.4 1.7 1 0 0 1 1 1 0 N terminus of Notch ligand RT_RNaseH_2 PF17919.1 GBG60603.1 - 4e-25 87.8 0.0 6.9e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60603.1 - 2.2e-21 76.1 0.0 3.8e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60603.1 - 7.5e-12 45.2 0.1 1.2e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LEA_2 PF03168.13 GBG60604.1 - 2e-12 47.5 0.6 4.2e-12 46.5 0.2 1.8 2 0 0 2 2 2 1 Late embryogenesis abundant protein Glyco_hydro_65C PF03633.15 GBG60604.1 - 0.18 11.7 0.2 0.42 10.5 0.2 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain Glutaredoxin PF00462.24 GBG60607.1 - 1.6e-18 66.7 0.0 2.9e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 GBG60607.1 - 0.00078 19.8 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SMP PF04927.12 GBG60607.1 - 0.0024 18.3 0.0 0.0061 17.0 0.0 1.7 1 0 0 1 1 1 1 Seed maturation protein DUF836 PF05768.14 GBG60607.1 - 0.0049 17.3 0.1 0.009 16.4 0.1 1.6 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 GBG60607.1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF659 PF04937.15 GBG60608.1 - 1.2e-30 106.4 0.0 1.6e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) NOA36 PF06524.12 GBG60608.1 - 1 8.6 3.3 1.5 8.0 3.3 1.3 1 0 0 1 1 1 0 NOA36 protein QWRF PF04484.12 GBG60609.1 - 5.3e-48 164.3 12.7 5.3e-48 164.3 12.7 5.9 5 2 1 6 6 6 2 QWRF family QWRF PF04484.12 GBG60611.1 - 3.6e-56 191.1 17.3 3.6e-56 191.1 17.3 5.1 3 2 1 4 4 4 1 QWRF family Mito_carr PF00153.27 GBG60612.1 - 7.3e-40 134.8 0.6 3.1e-15 55.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SSF PF00474.17 GBG60612.1 - 0.047 12.5 0.3 0.062 12.2 0.3 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family RRXRR PF14239.6 GBG60612.1 - 0.059 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 RRXRR protein DUF1242 PF06842.12 GBG60613.1 - 1.1 9.1 6.2 2.8 7.8 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) HSP90 PF00183.18 GBG60614.1 - 3.5e-236 785.1 27.0 4.7e-236 784.7 27.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GBG60614.1 - 4.1e-14 53.0 0.1 7.5e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GBG60614.1 - 9.5e-10 38.4 0.1 2.4e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Met_synt_B12 PF02965.17 GBG60614.1 - 0.014 14.9 0.1 0.044 13.2 0.1 1.8 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain LOH1CR12 PF10158.9 GBG60614.1 - 0.044 13.8 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Tumour suppressor protein RVT_1 PF00078.27 GBG60615.1 - 1.3e-68 230.8 1.9 6.3e-38 130.5 0.4 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) FA_desaturase PF00487.24 GBG60615.1 - 0.19 11.5 4.7 0.33 10.8 4.7 1.4 1 0 0 1 1 1 0 Fatty acid desaturase DUF659 PF04937.15 GBG60616.1 - 3.8e-33 114.5 0.0 5.7e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG60617.1 - 2.3e-16 60.1 0.0 3.9e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain FA_desaturase PF00487.24 GBG60617.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Integrase_H2C2 PF17921.1 GBG60617.1 - 0.0013 18.8 0.9 0.0031 17.6 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain APC_basic PF05956.11 GBG60618.1 - 0.023 14.2 0.5 0.023 14.2 0.5 2.0 1 1 1 2 2 2 0 APC basic domain Rad51 PF08423.11 GBG60618.1 - 0.032 13.5 0.0 0.083 12.1 0.0 1.6 1 1 1 2 2 2 0 Rad51 CALCOCO1 PF07888.11 GBG60619.1 - 0.02 13.8 30.9 0.042 12.7 30.9 1.5 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like RAP1 PF07218.11 GBG60619.1 - 0.043 12.1 7.8 0.063 11.6 7.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AAA_13 PF13166.6 GBG60619.1 - 4.2 5.9 12.0 6.2 5.3 12.0 1.2 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 GBG60619.1 - 7.4 6.0 10.0 15 5.1 10.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ICA69 PF04629.14 GBG60619.1 - 8.2 6.7 16.3 0.73 10.1 10.8 1.8 1 1 1 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain Sec2p PF06428.11 GBG60620.1 - 0.12 12.4 0.3 0.17 11.9 0.3 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p gag-asp_proteas PF13975.6 GBG60621.1 - 1.5e-08 35.1 0.0 3.7e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60621.1 - 7.1e-05 23.4 0.0 0.00017 22.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60621.1 - 0.00067 19.4 0.5 0.0012 18.7 0.5 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG60621.1 - 0.0027 18.0 0.0 0.0088 16.3 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60622.1 - 1.1e-08 35.5 0.0 2.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60622.1 - 5.1e-05 23.8 0.0 0.0001 22.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60622.1 - 0.0004 20.2 0.5 0.00068 19.4 0.5 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG60622.1 - 0.0014 18.9 0.0 0.0052 17.1 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease PTPRCAP PF15713.5 GBG60623.1 - 7 6.9 39.6 0.062 13.6 22.2 2.2 1 1 1 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated His_Phos_1 PF00300.22 GBG60624.1 - 7.7e-20 71.4 0.0 1.2e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 GBG60624.1 - 0.09 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) GST_N_2 PF13409.6 GBG60626.1 - 7.3e-09 35.8 0.2 2.4e-08 34.2 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain Stevor PF17410.2 GBG60626.1 - 4.7 6.7 4.9 10 5.6 4.9 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Ge1_WD40 PF16529.5 GBG60627.1 - 8.2e-21 74.3 0.0 2.8e-20 72.6 0.0 1.8 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 GBG60627.1 - 2.8e-08 34.3 0.1 0.0022 18.8 0.3 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF445 PF04286.12 GBG60627.1 - 0.011 15.6 12.7 0.019 14.8 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2267 PF10025.9 GBG60627.1 - 0.15 12.3 3.1 0.51 10.6 3.1 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) GerPC PF10737.9 GBG60627.1 - 0.98 9.5 13.8 0.067 13.3 3.5 3.1 2 1 2 4 4 4 0 Spore germination protein GerPC zf-RRPl_C4 PF17026.5 GBG60628.1 - 0.048 13.8 0.2 5.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Kinesin PF00225.23 GBG60629.1 - 7.4e-237 784.5 0.0 3.1e-117 391.2 0.0 2.9 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 GBG60629.1 - 2.6e-56 189.7 0.0 1.5e-26 93.1 0.0 3.3 2 0 0 2 2 2 2 Microtubule binding PIF1 PF05970.14 GBG60629.1 - 0.00012 21.4 0.5 0.53 9.4 0.1 2.8 2 0 0 2 2 2 2 PIF1-like helicase JHD PF17811.1 GBG60629.1 - 0.029 14.9 2.5 15 6.1 0.1 4.2 3 0 0 3 3 3 0 Jumonji helical domain 2-Hacid_dh PF00389.30 GBG60629.1 - 0.052 13.2 1.6 14 5.3 0.2 4.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MSL1_dimer PF16801.5 GBG60629.1 - 0.11 12.3 7.5 4.3 7.2 0.9 3.2 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 DUF4150 PF13665.6 GBG60629.1 - 0.12 12.5 0.0 22 5.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) 3H PF02829.14 GBG60629.1 - 0.13 12.6 4.6 9.6 6.6 0.3 3.9 3 0 0 3 3 2 0 3H domain DUF2439 PF10382.9 GBG60629.1 - 0.33 11.3 2.5 33 4.9 0.2 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Halogen_Hydrol PF10112.9 GBG60629.1 - 0.51 10.3 10.7 3.2 7.7 1.5 3.7 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein NCD3G PF07562.14 GBG60629.1 - 0.86 9.6 3.5 35 4.5 0.3 3.0 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DUF2087 PF09860.9 GBG60629.1 - 1.1 9.4 6.3 8.4 6.6 0.9 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF5403 PF17395.2 GBG60629.1 - 1.7 9.0 4.9 63 4.0 0.3 4.0 2 0 0 2 2 2 0 Family of unknown function (DUF5403) AAA_24 PF13479.6 GBG60629.1 - 5.6 6.6 7.5 36 4.0 0.0 4.1 3 0 0 3 3 3 0 AAA domain zf-RING_2 PF13639.6 GBG60630.1 - 6.3e-10 39.2 8.4 1e-09 38.5 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG60630.1 - 1.6e-07 31.1 7.8 2.6e-07 30.4 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG60630.1 - 6.2e-07 29.2 4.2 1e-06 28.5 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG60630.1 - 1.1e-06 28.8 9.3 3.9e-06 27.0 9.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GBG60630.1 - 2.3e-06 27.3 8.3 4.3e-06 26.5 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG60630.1 - 4.8e-06 26.5 4.4 8.3e-06 25.7 4.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GBG60630.1 - 0.0013 18.5 6.3 0.0023 17.8 6.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GBG60630.1 - 0.0039 16.9 4.0 0.0075 16.0 4.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 GBG60630.1 - 0.0075 16.2 5.7 0.013 15.4 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GBG60630.1 - 0.25 11.0 4.4 0.46 10.1 4.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GBG60630.1 - 0.48 10.5 4.6 1.6 8.9 4.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 GBG60630.1 - 1.1 9.4 5.8 1.9 8.7 5.8 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 GBG60630.1 - 1.2 9.0 2.8 2.6 7.9 2.9 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 GBG60630.1 - 1.6 9.0 4.7 5.8 7.2 4.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RT_RNaseH_2 PF17919.1 GBG60631.1 - 5.9e-33 112.9 0.0 1.2e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60631.1 - 7.3e-28 96.9 0.0 1.4e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60631.1 - 1.2e-08 34.7 0.3 2.3e-08 33.8 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG60631.1 - 6.4e-06 26.7 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60631.1 - 4.1e-05 24.1 0.0 8.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60631.1 - 0.039 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60631.1 - 0.05 13.4 0.4 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG60631.1 - 0.091 13.1 0.0 0.41 11.0 0.0 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein DUF1758 PF05585.12 GBG60631.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF454 PF04304.13 GBG60631.1 - 0.22 11.5 0.1 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF454) VHS PF00790.19 GBG60632.1 - 1.4e-30 106.0 0.0 2.5e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 GBG60632.1 - 1.6e-09 38.0 0.3 5.2e-09 36.3 0.3 1.9 1 0 0 1 1 1 1 GAT domain F-box-like PF12937.7 GBG60632.1 - 6.2e-06 26.0 2.2 8.6e-06 25.6 0.0 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 GBG60632.1 - 0.077 12.9 0.0 0.077 12.9 0.0 2.3 2 0 0 2 2 2 0 F-box domain Myb_DNA-bind_4 PF13837.6 GBG60633.1 - 2.6e-10 40.5 0.8 4.2e-10 39.9 0.8 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG60633.1 - 0.0064 16.8 0.1 0.011 16.0 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Epimerase PF01370.21 GBG60634.1 - 6.6e-77 258.2 0.0 8.3e-77 257.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GBG60634.1 - 2e-22 80.0 0.0 5.4e-21 75.3 0.0 2.4 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GBG60634.1 - 1.9e-09 37.0 0.0 4.1e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GBG60634.1 - 0.00022 20.5 0.8 0.00087 18.5 0.1 2.0 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GBG60634.1 - 0.001 19.0 0.0 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GBG60634.1 - 0.013 14.5 0.2 0.079 11.9 0.1 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RT_RNaseH PF17917.1 GBG60635.1 - 3.7e-23 81.8 0.0 7.1e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60635.1 - 1.4e-13 50.8 0.7 3.9e-13 49.3 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG60635.1 - 4e-13 49.2 0.0 8.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG60635.1 - 2.7e-12 46.4 0.0 2.4e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG60635.1 - 1.1e-10 41.7 0.0 3.9e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG60635.1 - 0.0049 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG60635.1 - 0.029 14.2 0.2 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like Hus1 PF04005.12 GBG60636.1 - 5.4e-55 186.6 0.0 5.9e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein DUF4746 PF15928.5 GBG60637.1 - 6.9 6.0 12.4 10 5.5 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Na_trans_assoc PF06512.13 GBG60637.1 - 9.4 6.5 15.6 0.44 10.8 10.3 1.5 2 0 0 2 2 2 0 Sodium ion transport-associated Peptidase_M41 PF01434.18 GBG60638.1 - 1.4e-49 168.5 9.8 1.2e-35 123.1 0.2 3.3 3 0 0 3 3 2 2 Peptidase family M41 AAA PF00004.29 GBG60638.1 - 1.6e-42 145.0 0.0 7.1e-42 143.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RVT_1 PF00078.27 GBG60638.1 - 1.1e-35 123.2 0.1 2.1e-35 122.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60638.1 - 3.7e-22 78.2 0.3 1.7e-21 76.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60638.1 - 1.7e-14 53.6 0.1 4.9e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain AAA_lid_3 PF17862.1 GBG60638.1 - 5.2e-12 45.4 0.1 1.8e-11 43.6 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain RT_RNaseH PF17917.1 GBG60638.1 - 7.1e-11 42.3 0.0 2.9e-10 40.4 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AAA_5 PF07728.14 GBG60638.1 - 1.3e-05 25.2 0.0 3.6e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG60638.1 - 0.0011 18.7 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GBG60638.1 - 0.0011 18.2 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GBG60638.1 - 0.0092 16.1 1.1 0.023 14.9 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 GBG60638.1 - 0.0098 16.3 0.1 0.0098 16.3 0.1 4.1 4 1 0 5 5 4 1 AAA ATPase domain IstB_IS21 PF01695.17 GBG60638.1 - 0.011 15.5 0.1 0.043 13.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 GBG60638.1 - 0.015 15.6 0.7 0.36 11.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 GBG60638.1 - 0.05 13.0 1.6 0.13 11.7 0.3 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GBG60638.1 - 0.12 11.9 0.0 0.64 9.5 0.0 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 GBG60638.1 - 0.12 12.9 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 1 0 AAA domain TadF PF16964.5 GBG60638.1 - 3.1 7.5 6.0 0.73 9.6 2.1 1.9 2 0 0 2 2 2 0 Putative tight adherence pilin protein F Chromosome_seg PF13889.6 GBG60639.1 - 2.5e-18 66.0 0.0 5.6e-18 64.9 0.0 1.6 1 1 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 GBG60639.1 - 4.6e-08 33.5 0.0 1.4e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) DNA_pol_phi PF04931.13 GBG60639.1 - 0.0027 15.9 25.5 0.0036 15.5 25.5 1.1 1 0 0 1 1 1 1 DNA polymerase phi CobT PF06213.12 GBG60639.1 - 7 6.0 16.3 11 5.4 16.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DSS1_SEM1 PF05160.13 GBG60640.1 - 5.5e-19 68.0 25.4 6.5e-19 67.8 25.4 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 GBG60640.1 - 0.0028 17.5 5.8 0.0028 17.5 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) Cwf_Cwc_15 PF04889.12 GBG60640.1 - 0.35 10.6 10.2 0.36 10.5 10.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein UCMA PF17085.5 GBG60640.1 - 3.1 7.8 11.0 3.3 7.7 10.6 1.3 1 1 0 1 1 1 0 Unique cartilage matrix associated protein DUF3527 PF12043.8 GBG60641.1 - 0.0053 16.4 2.8 0.0053 16.4 2.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) DUF2475 PF10629.9 GBG60641.1 - 0.054 13.7 4.2 2.9 8.2 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2475) WD40 PF00400.32 GBG60642.1 - 1.4e-31 108.0 10.8 2.2e-05 25.1 0.0 7.5 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG60642.1 - 5.3e-10 39.5 0.7 0.11 12.8 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG60642.1 - 0.00016 20.8 1.1 0.00046 19.2 1.1 1.8 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GBG60642.1 - 0.00022 21.2 0.1 0.0025 17.7 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 GBG60642.1 - 0.0057 16.4 0.0 2.3 7.9 0.0 3.0 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain GH97_C PF14509.6 GBG60644.1 - 0.21 11.8 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation HEAT PF02985.22 GBG60645.1 - 0.0066 16.6 0.0 0.022 15.0 0.0 1.9 1 0 0 1 1 1 1 HEAT repeat ParcG PF10274.9 GBG60645.1 - 0.028 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Parkin co-regulated protein HEAT_2 PF13646.6 GBG60645.1 - 0.035 14.5 0.2 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 HEAT repeats Ecm29 PF13001.7 GBG60645.1 - 0.038 12.7 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Proteasome stabiliser zf-CCHC_2 PF13696.6 GBG60646.1 - 0.0037 17.1 0.5 0.0067 16.2 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG60646.1 - 0.011 15.3 0.0 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG60646.1 - 0.038 14.2 0.1 0.25 11.6 0.1 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein DUF1664 PF07889.12 GBG60646.1 - 0.067 13.2 0.4 4.3 7.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rx_N PF18052.1 GBG60646.1 - 0.084 13.2 1.4 22 5.4 0.0 3.5 3 0 0 3 3 3 0 Rx N-terminal domain gag-asp_proteas PF13975.6 GBG60646.1 - 0.084 13.4 0.0 0.75 10.4 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG60646.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease ZapA PF05164.13 GBG60648.1 - 0.083 13.3 1.4 0.25 11.8 0.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapA Viral_P18 PF04521.13 GBG60649.1 - 0.059 13.2 0.2 3.9 7.3 0.0 3.0 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2014 PF09427.10 GBG60649.1 - 0.1 11.9 0.1 2 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2014) betaPIX_CC PF16523.5 GBG60650.1 - 0.029 14.2 0.3 0.047 13.5 0.3 1.3 1 0 0 1 1 1 0 betaPIX coiled coil TMF_DNA_bd PF12329.8 GBG60650.1 - 0.12 12.4 2.6 0.19 11.8 2.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 GBG60650.1 - 0.19 11.5 0.8 0.27 11.0 0.8 1.2 1 0 0 1 1 1 0 Septum formation initiator RVT_1 PF00078.27 GBG60651.1 - 2.1e-26 92.8 0.3 2.8e-26 92.4 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTRD1 PF17660.1 GBG60651.1 - 0.083 12.7 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 RT_RNaseH_2 PF17919.1 GBG60652.1 - 3.9e-67 222.6 0.7 5.9e-32 109.7 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60652.1 - 6e-57 190.4 0.5 8.9e-28 96.7 0.1 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG60652.1 - 1.8e-23 83.1 0.1 4.3e-23 81.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG60652.1 - 4.3e-22 78.5 0.2 2.6e-14 53.4 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG60652.1 - 6e-16 58.3 0.0 1.6e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG60652.1 - 0.0018 18.5 0.0 0.0058 16.8 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger ATP-grasp_6 PF18419.1 GBG60652.1 - 0.036 13.7 0.0 1.2 8.8 0.0 2.7 2 0 0 2 2 2 0 ATP-grasp-like domain DUF4168 PF13767.6 GBG60652.1 - 0.093 13.9 2.7 0.31 12.2 2.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) S_100 PF01023.19 GBG60652.1 - 0.18 11.5 0.5 15 5.4 0.1 2.9 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain DUF1690 PF07956.11 GBG60652.1 - 0.42 11.0 8.6 1.3 9.4 5.3 2.7 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF659 PF04937.15 GBG60653.1 - 8.6e-10 38.7 0.2 1.4e-09 38.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SDA1 PF05285.12 GBG60653.1 - 0.12 11.7 10.2 0.16 11.4 10.2 1.1 1 0 0 1 1 1 0 SDA1 Dimer_Tnp_hAT PF05699.14 GBG60654.1 - 0.16 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RT_RNaseH PF17917.1 GBG60656.1 - 7.8e-25 87.2 0.0 1.4e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60656.1 - 4.5e-24 84.4 0.0 8e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60656.1 - 0.004 16.7 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DsrH PF04077.12 GBG60657.1 - 0.0075 16.4 2.7 20 5.4 0.0 6.6 7 1 4 11 11 11 1 DsrH like protein DUF1870 PF08965.10 GBG60658.1 - 0.83 9.7 6.0 0.46 10.5 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1870) DUF4798 PF16055.5 GBG60658.1 - 1.3 9.3 19.0 0.048 13.9 5.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4798) MMPL PF03176.15 GBG60658.1 - 1.9 7.4 5.2 0.52 9.2 0.3 2.0 1 1 1 2 2 2 0 MMPL family DUF1043 PF06295.12 GBG60658.1 - 3.7 7.6 18.9 0.97 9.5 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) RVT_1 PF00078.27 GBG60659.1 - 3.1e-30 105.3 0.1 7.1e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60659.1 - 3.5e-30 104.0 0.0 6.6e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60659.1 - 1.7e-27 95.8 0.3 3.7e-27 94.7 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG60661.1 - 4.3e-22 78.5 0.0 1.8e-18 66.7 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60661.1 - 9.7e-09 35.1 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein CDC45 PF02724.14 GBG60661.1 - 0.04 12.2 21.0 0.066 11.5 21.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DDE_Tnp_1_2 PF13586.6 GBG60661.1 - 0.12 12.8 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Transposase DDE domain Nop25 PF09805.9 GBG60661.1 - 2.2 8.8 11.3 3.1 8.2 11.3 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SDA1 PF05285.12 GBG60661.1 - 3.1 7.1 35.0 4.1 6.7 35.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG60661.1 - 4.8 5.3 33.0 6.3 4.9 33.0 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG60661.1 - 5.9 5.2 23.8 7.9 4.8 23.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Glyco_hydro_63 PF03200.16 GBG60662.1 - 5.8e-203 675.1 0.1 6.9e-203 674.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 GBG60662.1 - 5.1e-39 134.7 0.9 5.1e-39 134.7 0.9 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 GBG60662.1 - 0.0013 17.7 0.2 0.0022 17.0 0.2 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 GBG60662.1 - 0.099 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Trehalase FimH_man-bind PF09160.10 GBG60663.1 - 0.16 11.6 0.1 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 FimH, mannose binding GTP_EFTU PF00009.27 GBG60664.1 - 1.5e-53 181.2 0.0 2.2e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GBG60664.1 - 4.4e-39 133.3 0.1 1e-38 132.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GBG60664.1 - 8.8e-14 51.7 0.2 8.8e-14 51.7 0.2 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG60664.1 - 0.00017 21.6 0.3 0.00078 19.5 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GBG60664.1 - 0.00022 20.7 0.1 0.0042 16.5 0.1 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 GBG60664.1 - 0.026 14.4 2.7 0.043 13.7 0.2 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Mt_ATP-synt_D PF05873.12 GBG60664.1 - 0.071 13.0 0.2 4.7 7.0 0.0 3.0 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Dynamin_N PF00350.23 GBG60664.1 - 0.12 12.4 0.3 17 5.4 0.2 2.4 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 GBG60664.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 GBG60665.1 - 1e-45 156.2 0.0 1.3e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG60665.1 - 3e-28 98.6 0.0 4.1e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 GBG60665.1 - 0.0073 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein Kinesin PF00225.23 GBG60666.1 - 2.2e-47 161.6 0.0 3.2e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF659 PF04937.15 GBG60666.1 - 1.1e-28 100.1 0.7 3.2e-28 98.5 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Kinesin PF00225.23 GBG60667.1 - 3.6e-38 131.3 0.0 5.5e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF659 PF04937.15 GBG60667.1 - 1.1e-28 100.0 0.7 2.9e-28 98.6 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG60668.1 - 3.3e-31 107.3 0.0 6e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60668.1 - 2.2e-27 95.4 0.1 4.4e-27 94.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60668.1 - 4.2e-19 68.4 0.2 1.7e-18 66.5 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG60668.1 - 6.9e-15 55.3 0.2 3.7e-14 52.9 0.1 2.2 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG60668.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.7 3 0 0 3 3 3 0 H2C2 zinc finger Phage_spike_2 PF18781.1 GBG60669.1 - 9.3e-06 25.6 0.0 0.95 9.5 0.0 3.3 3 0 0 3 3 3 3 Phage spike trimer UCH PF00443.29 GBG60669.1 - 0.014 14.9 2.6 0.18 11.2 0.1 3.3 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Kinesin PF00225.23 GBG60669.1 - 0.12 11.3 0.1 0.12 11.3 0.1 3.0 3 0 0 3 3 3 0 Kinesin motor domain IQ PF00612.27 GBG60671.1 - 3.2e-58 188.1 164.5 7.7e-05 22.1 0.3 27.0 27 0 0 27 27 27 23 IQ calmodulin-binding motif RT_RNaseH PF17917.1 GBG60671.1 - 1.6e-13 50.8 1.3 5.5e-13 49.1 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase CH PF00307.31 GBG60671.1 - 7.5e-12 45.4 0.3 0.00013 22.1 0.0 4.2 4 0 0 4 4 4 2 Calponin homology (CH) domain RVP_2 PF08284.11 GBG60671.1 - 1e-07 31.8 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease ASH PF15780.5 GBG60671.1 - 1.2e-07 31.9 0.1 0.007 16.5 0.0 2.6 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Asp_protease_2 PF13650.6 GBG60671.1 - 2.6e-06 28.0 0.0 6.9e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG60671.1 - 2.8e-06 27.3 0.0 8.3e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CAMSAP_CH PF11971.8 GBG60671.1 - 6e-06 26.0 0.0 0.0016 18.2 0.0 2.8 2 0 0 2 2 2 1 CAMSAP CH domain rve PF00665.26 GBG60671.1 - 6.5e-06 26.3 0.0 3.4e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG60671.1 - 7.1e-05 23.3 0.0 0.00022 21.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease CH_2 PF06294.11 GBG60671.1 - 0.14 12.3 0.0 6.8 6.9 0.0 3.0 2 0 0 2 2 2 0 CH-like domain in sperm protein IQ PF00612.27 GBG60672.1 - 1.6e-58 189.0 164.5 7.5e-05 22.2 0.3 27.0 27 0 0 27 27 27 23 IQ calmodulin-binding motif RT_RNaseH PF17917.1 GBG60672.1 - 1.6e-13 50.9 1.3 5.3e-13 49.2 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase CH PF00307.31 GBG60672.1 - 9.5e-11 41.8 0.1 0.00013 22.2 0.0 3.3 3 0 0 3 3 3 2 Calponin homology (CH) domain RVP_2 PF08284.11 GBG60672.1 - 9.7e-08 31.9 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease ASH PF15780.5 GBG60672.1 - 1.1e-07 32.0 0.1 0.0068 16.6 0.0 2.6 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Asp_protease_2 PF13650.6 GBG60672.1 - 2.5e-06 28.0 0.0 6.8e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG60672.1 - 2.7e-06 27.3 0.0 8.1e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CAMSAP_CH PF11971.8 GBG60672.1 - 6.1e-06 26.0 0.0 0.0015 18.3 0.0 2.7 2 0 0 2 2 2 1 CAMSAP CH domain rve PF00665.26 GBG60672.1 - 1.1e-05 25.6 0.0 3.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG60672.1 - 6.8e-05 23.4 0.0 0.00021 21.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease CH_2 PF06294.11 GBG60672.1 - 0.1 12.7 0.0 4.1 7.6 0.0 2.9 2 0 0 2 2 2 0 CH-like domain in sperm protein Myb_DNA-bind_4 PF13837.6 GBG60673.1 - 3.6e-06 27.3 3.1 7.7e-06 26.2 3.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG60673.1 - 0.005 16.9 1.4 0.01 15.9 0.7 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG60673.1 - 0.021 15.0 0.2 0.067 13.4 0.2 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain SP_C-Propep PF08999.10 GBG60673.1 - 0.022 14.5 7.7 0.044 13.6 7.7 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide NUC153 PF08159.12 GBG60674.1 - 4.2e-11 42.4 3.2 9.8e-11 41.3 3.2 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 GBG60674.1 - 0.12 13.2 0.4 4.5 8.3 0.1 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG60674.1 - 0.2 11.9 0.0 0.66 10.3 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 GBG60675.1 - 9e-26 90.8 0.1 1.4e-25 90.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60675.1 - 3.4e-22 78.3 0.0 1.2e-21 76.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60675.1 - 6.7e-18 64.9 0.0 2.2e-17 63.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG60675.1 - 3.4e-07 30.8 0.0 1.2e-06 29.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60675.1 - 1.8e-06 28.4 0.0 7.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG60675.1 - 0.00013 21.8 0.0 0.00038 20.2 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60675.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG60675.1 - 0.022 15.1 7.6 0.14 12.4 0.2 4.2 4 0 0 4 4 4 0 Retrotransposon gag protein p450 PF00067.22 GBG60676.1 - 1.7e-85 287.6 0.0 2.3e-63 214.6 0.0 4.2 3 1 0 3 3 3 2 Cytochrome P450 Retrotrans_gag PF03732.17 GBG60676.1 - 3.1e-05 24.1 5.4 0.62 10.4 0.0 4.5 4 0 0 4 4 4 2 Retrotransposon gag protein RVT_1 PF00078.27 GBG60677.1 - 7.8e-23 81.2 0.1 1.2e-22 80.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.22 GBG60678.1 - 4.8e-87 292.6 0.0 1.2e-65 222.1 0.0 3.4 3 1 0 3 3 3 3 Cytochrome P450 p450 PF00067.22 GBG60679.1 - 8.1e-84 282.0 0.0 2.4e-64 217.8 0.0 3.0 3 0 0 3 3 3 2 Cytochrome P450 RT_RNaseH_2 PF17919.1 GBG60679.1 - 5.4e-32 109.8 0.0 1.3e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60679.1 - 3.4e-29 101.2 0.0 7e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG60679.1 - 1.9 6.6 23.9 2.8 6.1 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 GBG60679.1 - 6.1 5.8 11.2 11 5.0 11.2 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 GBG60679.1 - 6.3 5.0 19.8 9.8 4.3 19.8 1.2 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.22 GBG60680.1 - 1.3e-85 287.9 0.0 1e-63 215.8 0.0 3.2 3 1 0 3 3 3 2 Cytochrome P450 Menin PF05053.13 GBG60682.1 - 8 4.7 9.3 9.6 4.4 9.3 1.1 1 0 0 1 1 1 0 Menin Zein-binding PF04576.15 GBG60683.1 - 1e-22 80.2 18.0 4e-22 78.3 18.0 2.1 1 0 0 1 1 1 1 Zein-binding PPDK_N PF01326.19 GBG60684.1 - 1.8e-17 63.6 0.0 7.5e-11 41.9 0.0 4.0 2 2 2 4 4 4 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM53 PF16760.5 GBG60684.1 - 0.01 16.4 0.3 0.033 14.8 0.3 1.8 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Abhydrolase_3 PF07859.13 GBG60686.1 - 4.1e-13 49.7 0.0 1.2e-12 48.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GBG60686.1 - 5.3e-09 35.5 0.6 1.2e-08 34.4 0.6 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 GBG60686.1 - 6.5e-05 22.5 0.1 0.00031 20.3 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GBG60686.1 - 0.00012 22.7 1.2 0.00026 21.7 1.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG60686.1 - 0.0003 20.1 0.1 0.26 10.5 0.0 2.7 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG60686.1 - 0.0012 18.5 0.9 0.0027 17.4 0.7 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GBG60686.1 - 0.11 12.2 0.1 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DNA_pol_phi PF04931.13 GBG60687.1 - 0.36 8.9 27.9 0.42 8.7 27.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi RVT_1 PF00078.27 GBG60688.1 - 5.1e-22 78.5 0.0 9.2e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG60688.1 - 1.5e-09 37.8 0.0 2.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60688.1 - 5.6e-07 30.1 0.0 1.1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60688.1 - 1.6e-06 28.6 0.0 3.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60688.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Mannitol_dh_C PF08125.13 GBG60689.1 - 0.066 12.7 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain FERM_f0 PF16511.5 GBG60689.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM APOBEC_C PF05240.14 GBG60689.1 - 0.14 12.1 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 APOBEC-like C-terminal domain DUF659 PF04937.15 GBG60691.1 - 2.5e-14 53.4 0.0 3.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) p450 PF00067.22 GBG60692.1 - 2.6e-71 240.8 0.1 2.1e-50 171.8 0.1 3.2 3 1 1 4 4 4 3 Cytochrome P450 RT_RNaseH PF17917.1 GBG60693.1 - 2.8e-29 101.5 1.0 4.7e-29 100.7 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60693.1 - 8.1e-21 73.9 0.0 1.8e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60693.1 - 1.6e-12 47.4 1.2 5.8e-12 45.5 1.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG60693.1 - 0.098 12.3 0.1 0.098 12.3 0.1 3.1 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DDE_Tnp_4 PF13359.6 GBG60694.1 - 1.3e-13 50.9 1.4 2.8e-13 49.8 0.0 2.2 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60694.1 - 1.3e-06 28.1 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG60694.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain DUF4499 PF14934.6 GBG60695.1 - 0.051 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Shisa PF13908.6 GBG60695.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RT_RNaseH_2 PF17919.1 GBG60696.1 - 1.8e-25 88.9 0.0 5.1e-25 87.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60696.1 - 3.3e-24 85.2 0.0 7.5e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60696.1 - 3.9e-16 58.9 0.1 8.2e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG60696.1 - 2.3e-13 50.2 0.0 6e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG60696.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 zf-C2H2 PF00096.26 GBG60698.1 - 0.14 12.7 3.9 0.34 11.5 3.9 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GBG60698.1 - 0.74 10.8 5.1 1.1 10.3 3.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Prefoldin PF02996.17 GBG60700.1 - 1.7e-22 79.5 0.1 2.1e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Exo84_C PF16528.5 GBG60700.1 - 0.031 14.1 0.3 0.043 13.6 0.3 1.2 1 0 0 1 1 1 0 Exocyst component 84 C-terminal End3 PF12761.7 GBG60700.1 - 0.086 13.0 0.1 0.094 12.9 0.1 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 RCDG1 PF15725.5 GBG60701.1 - 0.0094 16.3 2.4 0.013 15.9 2.4 1.2 1 0 0 1 1 1 1 Renal cancer differentiation gene 1 protein Amidase PF01425.21 GBG60702.1 - 5.9e-150 500.2 0.0 7.5e-150 499.8 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF3326 PF11805.8 GBG60703.1 - 1.8e-90 303.2 6.2 1.3e-56 191.9 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3326) ABC_tran PF00005.27 GBG60704.1 - 4.6e-24 85.5 0.2 1.9e-23 83.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG60704.1 - 4.2e-19 68.9 11.9 7.1e-19 68.1 11.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG60704.1 - 4.7e-09 36.5 0.0 3.8e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 GBG60704.1 - 0.0066 17.1 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) Herpes_capsid PF06112.11 GBG60704.1 - 0.015 15.3 0.8 0.034 14.2 0.0 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein SMC_N PF02463.19 GBG60704.1 - 0.13 11.7 0.0 3.1 7.2 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Myb_DNA-bind_4 PF13837.6 GBG60707.1 - 0.00018 21.8 4.8 0.0002 21.7 3.4 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain GldM_N PF12081.8 GBG60707.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 GldM N-terminal domain DDE_Tnp_4 PF13359.6 GBG60708.1 - 4.8e-07 29.6 0.0 1.4e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60708.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Plant transposon protein AAA_21 PF13304.6 GBG60709.1 - 9.5e-08 32.2 0.0 1.5e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 GBG60709.1 - 0.0007 20.1 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF4162 PF13732.6 GBG60709.1 - 0.0026 18.5 0.0 0.005 17.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) DUF3537 PF12056.8 GBG60710.1 - 4.3e-73 246.4 7.8 5.3e-73 246.1 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3537) Host_attach PF10116.9 GBG60712.1 - 1.9 9.1 12.1 0.037 14.6 2.2 2.8 2 0 0 2 2 2 0 Protein required for attachment to host cells RVT_1 PF00078.27 GBG60713.1 - 5e-06 26.2 0.0 8.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG60713.1 - 0.017 15.7 0.0 0.041 14.4 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1639 PF07797.14 GBG60713.1 - 1.4 9.0 3.2 11 6.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) DUF3537 PF12056.8 GBG60714.1 - 2e-72 244.2 2.9 2.7e-72 243.8 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3537) 7tm_7 PF08395.12 GBG60714.1 - 0.00035 19.9 12.5 0.00062 19.1 12.5 1.3 1 0 0 1 1 1 1 7tm Chemosensory receptor GPDPase_memb PF10110.9 GBG60714.1 - 0.47 9.2 10.7 0.019 13.7 4.7 1.6 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase PEX11 PF05648.14 GBG60715.1 - 7.5e-30 104.1 0.0 9.5e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RVT_1 PF00078.27 GBG60716.1 - 1.7e-11 44.1 0.0 1.3e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lant_dehydr_N PF04738.13 GBG60716.1 - 0.018 13.2 0.1 0.025 12.7 0.1 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus DUF1775 PF07987.11 GBG60717.1 - 0.012 15.9 3.6 0.02 15.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unkown function (DUF1775) SNF2_N PF00176.23 GBG60719.1 - 7.8e-65 218.9 0.0 7.8e-65 218.9 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG60719.1 - 2.6e-16 59.9 0.2 1.8e-15 57.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Velvet PF11754.8 GBG60719.1 - 0.00027 21.0 4.3 0.00027 21.0 4.3 4.0 3 1 0 3 3 3 1 Velvet factor TFIIA PF03153.13 GBG60719.1 - 0.0015 18.6 44.1 0.0015 18.6 44.1 8.2 5 1 3 8 8 8 1 Transcription factor IIA, alpha/beta subunit zf-CCHC PF00098.23 GBG60721.1 - 0.00013 21.8 5.6 0.00013 21.8 5.6 2.0 2 0 0 2 2 2 1 Zinc knuckle DUF4363 PF14276.6 GBG60721.1 - 0.057 13.5 1.2 0.057 13.5 1.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) zf_ZIC PF18366.1 GBG60721.1 - 0.22 11.6 1.6 14 5.9 0.6 3.1 3 0 0 3 3 3 0 Zic proteins zinc finger domain Hid1 PF12722.7 GBG60721.1 - 0.9 7.6 7.0 1.3 7.1 7.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U1snRNP70_N PF12220.8 GBG60721.1 - 1.4 9.6 16.7 5.2 7.8 7.9 3.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ALMT PF11744.8 GBG60721.1 - 5.1 5.8 7.7 6.3 5.5 7.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Mlo PF03094.15 GBG60723.1 - 2.3e-118 395.6 5.8 5.9e-97 325.0 4.5 2.0 2 0 0 2 2 2 2 Mlo family RVT_1 PF00078.27 GBG60724.1 - 5.7e-28 97.9 0.1 1.8e-27 96.3 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60724.1 - 1.1e-23 83.1 0.0 3.7e-23 81.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60724.1 - 4.5e-23 81.5 0.0 1.3e-22 80.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG60724.1 - 1.1e-07 32.4 0.0 2.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60724.1 - 2.5e-06 27.9 0.0 6.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG60724.1 - 1.1e-05 25.2 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG60724.1 - 1.8e-05 24.7 0.1 4.3e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG60724.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Hemerythrin PF01814.23 GBG60724.1 - 0.41 11.3 0.1 0.41 11.3 0.1 3.4 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain RVT_1 PF00078.27 GBG60726.1 - 1.4e-25 90.2 0.0 2.9e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60726.1 - 2e-08 34.1 0.0 5.6e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG60726.1 - 0.0062 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4407 PF14362.6 GBG60726.1 - 0.47 9.8 12.2 1.5 8.1 9.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) BAF1_ABF1 PF04684.13 GBG60727.1 - 0.57 9.2 28.3 0.89 8.5 28.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cwf_Cwc_15 PF04889.12 GBG60727.1 - 1.8 8.3 25.8 2.1 8.0 10.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GBG60727.1 - 9.4 5.5 16.7 12 5.1 16.7 1.1 1 0 0 1 1 1 0 BUD22 RVT_1 PF00078.27 GBG60728.1 - 0.00027 20.5 0.0 0.45 10.0 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TTL PF03133.15 GBG60729.1 - 1.9e-67 227.5 0.0 2.3e-35 122.2 0.0 3.3 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GBG60729.1 - 2.5e-07 30.2 0.1 4.1e-05 23.0 0.0 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 GBG60729.1 - 0.00043 19.6 0.0 0.01 15.1 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp FUSC PF04632.12 GBG60731.1 - 1.2e-24 86.9 13.2 1.1e-23 83.7 6.4 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein family FUSC_2 PF13515.6 GBG60731.1 - 1e-11 45.1 18.9 1.6e-11 44.4 10.7 2.9 2 1 1 3 3 3 2 Fusaric acid resistance protein-like ALMT PF11744.8 GBG60731.1 - 4.3e-06 25.8 5.4 0.00025 20.0 2.6 2.5 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_1 PF06081.11 GBG60731.1 - 0.0012 19.0 7.4 0.0012 19.0 7.4 2.5 2 0 0 2 2 2 1 Aromatic acid exporter family member 1 AdoHcyase_NAD PF00670.21 GBG60731.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RVT_1 PF00078.27 GBG60732.1 - 3.2e-24 85.7 0.1 4.6e-24 85.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60732.1 - 0.00066 19.7 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3632 PF12311.8 GBG60732.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) Cactin_mid PF10312.9 GBG60733.1 - 0.096 12.4 0.2 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Conserved mid region of cactin zf-CCHC_2 PF13696.6 GBG60736.1 - 1.2 9.0 3.2 2.3 8.1 3.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Dimer_Tnp_hAT PF05699.14 GBG60738.1 - 0.054 13.3 0.1 0.094 12.5 0.1 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region PBP1_TM PF14812.6 GBG60738.1 - 0.58 10.6 5.6 1.7 9.1 5.6 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 GBG60738.1 - 0.63 9.7 6.9 1 9.0 6.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 GBG60738.1 - 2.9 8.0 11.3 0.051 13.7 3.9 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.12 GBG60738.1 - 4.1 5.5 6.0 5 5.2 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH PF17917.1 GBG60739.1 - 7.9e-28 96.8 0.3 1.5e-27 95.9 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60739.1 - 1.8e-21 76.0 0.1 3.7e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60739.1 - 6.1e-19 67.9 1.1 1.2e-18 66.9 1.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60739.1 - 1.1e-15 57.8 0.0 3.2e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG60739.1 - 1.2e-06 28.9 0.0 4.3e-06 27.2 0.0 2.0 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG60739.1 - 3.2e-06 27.3 0.1 7.5e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG60739.1 - 2.8e-05 24.7 0.0 6.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG60739.1 - 0.0036 17.2 0.3 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG60739.1 - 0.02 14.6 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.12 GBG60739.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF1564 PF07600.11 GBG60739.1 - 0.026 14.2 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Asp_protease PF09668.10 GBG60739.1 - 0.045 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease ApbE PF02424.15 GBG60740.1 - 3.4e-48 164.4 0.0 4.5e-35 121.4 0.0 2.1 2 0 0 2 2 2 2 ApbE family DUF659 PF04937.15 GBG60742.1 - 2.2e-16 60.1 0.0 3.6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60742.1 - 1.1e-05 25.1 0.0 2.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Astro_capsid_p PF12226.8 GBG60743.1 - 1.6 7.8 8.2 2.1 7.4 8.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop53 PF07767.11 GBG60743.1 - 4.2 6.6 16.7 5.4 6.3 16.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) zf-CCHC PF00098.23 GBG60744.1 - 5.2e-06 26.3 1.7 8.8e-06 25.6 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG60744.1 - 0.00057 19.6 5.3 0.00092 19.0 5.3 1.3 1 0 0 1 1 1 1 Zinc knuckle NPR3 PF03666.13 GBG60745.1 - 0.64 8.7 4.3 0.73 8.5 4.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3742 PF12553.8 GBG60747.1 - 2.4 8.3 4.4 8.3 6.6 4.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Aldo_ket_red PF00248.21 GBG60748.1 - 2.7e-16 59.6 0.0 4.1e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Integrase_H2C2 PF17921.1 GBG60748.1 - 3e-16 59.3 0.1 5.7e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60748.1 - 6.6e-07 29.5 0.1 1.5e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG60749.1 - 4.3e-27 95.1 0.1 7.4e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60749.1 - 4.7e-09 36.2 0.0 1.4e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG60749.1 - 1.5e-07 31.9 0.0 4e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60749.1 - 1.9e-07 31.6 0.0 5.2e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60749.1 - 8e-06 25.7 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60749.1 - 7.1e-05 22.6 0.0 0.00021 21.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG60749.1 - 0.0065 16.7 4.6 0.033 14.4 2.4 3.3 2 1 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG60749.1 - 0.069 13.4 0.0 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Aldo_ket_red PF00248.21 GBG60750.1 - 6.3e-45 153.6 0.0 1e-44 152.9 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family RT_RNaseH_2 PF17919.1 GBG60750.1 - 8.8e-35 118.8 0.0 2.1e-34 117.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60750.1 - 1.3e-28 99.4 0.0 3.1e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG60750.1 - 2.5e-15 56.7 0.2 2.6e-14 53.4 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG60750.1 - 4.5e-15 55.5 0.0 9e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DUF668 PF05003.12 GBG60751.1 - 1.3e-25 89.7 0.4 3.6e-25 88.2 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF668) DUF3475 PF11961.8 GBG60751.1 - 2e-14 53.4 0.4 5e-14 52.1 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3475) Vinculin PF01044.19 GBG60751.1 - 0.53 8.4 3.4 0.93 7.6 3.4 1.3 1 0 0 1 1 1 0 Vinculin family Myc_N PF01056.18 GBG60751.1 - 4.3 7.2 14.2 17 5.1 11.6 2.6 2 0 0 2 2 2 0 Myc amino-terminal region RVT_1 PF00078.27 GBG60752.1 - 1.4e-30 106.5 0.0 2.4e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG60752.1 - 1.3e-22 80.4 0.0 1.8e-21 76.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG60752.1 - 4.9e-21 75.3 0.0 5e-20 72.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain SRP-alpha_N PF04086.13 GBG60752.1 - 0.11 12.4 1.6 0.18 11.7 1.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 GBG60752.1 - 0.59 8.3 2.0 0.87 7.8 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein GATase_7 PF13537.6 GBG60753.1 - 5.4e-13 48.9 0.0 4.1e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase domain DUF3700 PF12481.8 GBG60753.1 - 1.1e-10 41.3 0.0 6.6e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Aluminium induced protein GATase_6 PF13522.6 GBG60753.1 - 3.4e-07 30.5 0.0 7.7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF4187 PF13821.6 GBG60754.1 - 0.00075 19.2 0.7 0.0022 17.7 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG60754.1 - 0.005 17.1 0.2 0.02 15.2 0.2 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein DDE_Tnp_4 PF13359.6 GBG60758.1 - 8.6e-17 61.3 0.0 1.7e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60758.1 - 4.2e-05 23.2 0.0 6.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein BNR PF02012.20 GBG60760.1 - 0.59 10.3 1.9 1.1 9.5 0.2 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat Hamartin PF04388.12 GBG60760.1 - 1.2 7.7 2.1 1.7 7.2 2.1 1.1 1 0 0 1 1 1 0 Hamartin protein Glyco_transf_64 PF09258.10 GBG60761.1 - 3.9e-70 235.9 0.0 4.7e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Apt1 PF10351.9 GBG60761.1 - 0.12 11.2 2.0 0.15 10.9 2.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CSG2 PF16965.5 GBG60761.1 - 0.16 10.9 0.1 0.24 10.3 0.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Secretin_N_2 PF07655.13 GBG60761.1 - 0.2 12.2 13.1 0.34 11.5 13.1 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain SR-25 PF10500.9 GBG60761.1 - 0.55 9.8 24.3 0.99 9.0 24.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 GBG60761.1 - 8 4.9 8.9 10 4.5 8.9 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_transf_64 PF09258.10 GBG60762.1 - 1.4e-68 230.8 0.0 1.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain SPX PF03105.19 GBG60762.1 - 0.0022 18.0 1.3 0.0024 17.9 1.3 1.1 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 GBG60762.1 - 0.032 13.1 6.6 0.041 12.7 6.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CSG2 PF16965.5 GBG60762.1 - 0.071 12.1 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Secretin_N_2 PF07655.13 GBG60762.1 - 0.079 13.5 17.2 0.14 12.7 17.2 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Glyco_tranf_2_3 PF13641.6 GBG60762.1 - 0.11 12.4 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF1180 PF06679.12 GBG60762.1 - 0.62 10.5 4.0 1 9.7 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 GBG60762.1 - 1.4 7.4 13.0 1.8 7.0 13.0 1.1 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 GBG60762.1 - 1.7 8.3 10.2 2.6 7.7 10.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4614 PF15391.6 GBG60762.1 - 6.1 6.8 18.8 11 6.0 18.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CDK2AP PF09806.9 GBG60762.1 - 8.8 6.3 14.4 14 5.7 14.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein StbA PF06406.11 GBG60763.1 - 0.74 9.0 2.0 1.1 8.4 2.0 1.2 1 0 0 1 1 1 0 StbA protein DUF4193 PF13834.6 GBG60763.1 - 2.5 8.6 6.1 1.9 9.0 3.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4193) DASH_Dad2 PF08654.10 GBG60765.1 - 0.84 10.1 5.6 0.25 11.8 0.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 Retrotrans_gag PF03732.17 GBG60766.1 - 0.047 14.0 0.0 0.2 12.0 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein CBM_6 PF03422.15 GBG60770.1 - 1.3e-69 232.3 0.0 1.6e-22 80.1 0.0 3.1 3 0 0 3 3 3 3 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GBG60770.1 - 7.6e-15 55.0 0.0 0.0015 18.6 0.0 3.3 3 0 0 3 3 3 3 DUF5010 C-terminal domain FimA PF16970.5 GBG60770.1 - 0.015 15.5 0.0 0.87 9.8 0.0 2.4 2 0 0 2 2 2 0 Type-1 fimbrial protein, A CUE PF02845.16 GBG60771.1 - 0.12 12.1 0.1 12 5.7 0.0 3.1 3 0 0 3 3 3 0 CUE domain F-box-like PF12937.7 GBG60772.1 - 4.2e-08 32.9 0.6 1e-07 31.7 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG60772.1 - 8e-06 25.6 0.4 1.8e-05 24.5 0.4 1.6 1 0 0 1 1 1 1 F-box domain DUF2781 PF10914.8 GBG60774.1 - 0.029 14.8 0.1 0.043 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) 7tm_6 PF02949.20 GBG60774.1 - 0.03 13.4 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 7tm Odorant receptor CHAT PF12770.7 GBG60775.1 - 1.4e-08 34.5 0.1 3.9e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 CHAT domain CHAT PF12770.7 GBG60776.1 - 1.3e-41 142.9 0.0 1.2e-23 84.0 0.0 2.4 2 0 0 2 2 2 2 CHAT domain Asp_protease_2 PF13650.6 GBG60777.1 - 0.017 15.7 0.2 0.039 14.6 0.2 1.7 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG60777.1 - 0.095 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG60777.1 - 0.37 10.5 1.6 0.47 10.2 0.2 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like A_deamin PF02137.18 GBG60780.1 - 5.8e-78 262.6 0.0 8e-36 124.1 0.0 3.3 3 0 0 3 3 3 3 Adenosine-deaminase (editase) domain SSF PF00474.17 GBG60780.1 - 1.4e-23 83.5 24.1 2.2e-23 82.8 24.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family LPP PF04728.13 GBG60782.1 - 4e-05 23.9 5.9 0.66 10.4 0.1 4.9 3 1 0 3 3 3 1 Lipoprotein leucine-zipper zf-CCHC PF00098.23 GBG60782.1 - 8.5e-05 22.5 2.0 0.00014 21.7 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Fzo_mitofusin PF04799.13 GBG60782.1 - 0.04 13.5 2.9 0.82 9.2 0.1 2.5 1 1 1 2 2 2 0 fzo-like conserved region SWI-SNF_Ssr4 PF08549.10 GBG60782.1 - 0.056 12.1 8.1 0.069 11.8 8.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Spc7 PF08317.11 GBG60782.1 - 0.092 11.6 22.4 0.64 8.8 15.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_Gp23 PF10669.9 GBG60782.1 - 0.14 12.5 10.1 0.26 11.6 10.1 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) zf-CCHC_4 PF14392.6 GBG60782.1 - 0.16 11.7 0.5 0.33 10.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Pinin_SDK_memA PF04696.13 GBG60782.1 - 0.64 10.1 20.6 2.6 8.1 13.9 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF4407 PF14362.6 GBG60782.1 - 0.73 9.1 18.4 2.1 7.7 18.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 GBG60782.1 - 0.76 9.1 11.2 1.2 8.5 11.2 1.2 1 0 0 1 1 1 0 FAM76 protein RT_RNaseH_2 PF17919.1 GBG60783.1 - 1.2e-26 92.7 0.0 2e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60783.1 - 2.3e-23 82.5 0.0 3.8e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60783.1 - 1.6e-11 44.1 0.2 2.4e-11 43.6 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG60783.1 - 0.38 10.1 12.0 0.52 9.7 12.0 1.1 1 0 0 1 1 1 0 SDA1 DUF4691 PF15762.5 GBG60783.1 - 0.6 10.2 10.2 1.1 9.4 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) CDC45 PF02724.14 GBG60783.1 - 1.4 7.2 9.4 1.9 6.7 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG60783.1 - 2.8 6.0 12.8 3.6 5.7 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family Rhomboid PF01694.22 GBG60784.1 - 6.2e-24 84.7 16.2 1.2e-23 83.8 16.2 1.5 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 GBG60784.1 - 0.00027 20.9 8.6 0.00062 19.7 8.6 1.6 1 1 0 1 1 1 1 Der1-like family LpxC PF03331.13 GBG60786.1 - 1.4e-74 251.0 0.0 1.1e-65 221.9 0.0 2.4 2 1 0 2 2 2 2 UDP-3-O-acyl N-acetylglycosamine deacetylase AAA_18 PF13238.6 GBG60787.1 - 1.2e-06 29.1 0.0 4.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GBG60787.1 - 0.00036 20.7 0.1 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 GBG60787.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 GBG60787.1 - 0.037 14.3 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 GBG60787.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 GBG60787.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_16 PF13191.6 GBG60787.1 - 0.077 13.4 0.0 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Na_trans_assoc PF06512.13 GBG60788.1 - 5.7e-06 26.8 11.6 5.7e-06 26.8 11.6 2.9 2 1 1 3 3 3 1 Sodium ion transport-associated zf-CCHC PF00098.23 GBG60788.1 - 0.00013 21.9 3.3 0.00035 20.5 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle AAA_23 PF13476.6 GBG60788.1 - 0.01 16.4 15.6 0.01 16.4 15.6 3.2 3 1 0 3 3 3 1 AAA domain zf-CCHC_3 PF13917.6 GBG60788.1 - 0.12 12.4 1.7 0.36 10.8 1.7 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG60788.1 - 0.14 11.9 0.7 0.31 10.8 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle AAA_16 PF13191.6 GBG60789.1 - 5e-08 33.5 0.2 3.7e-07 30.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 GBG60789.1 - 3e-06 27.3 0.0 2.5e-05 24.3 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.13 GBG60789.1 - 0.00021 20.5 0.0 0.00047 19.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 GBG60789.1 - 0.00064 19.7 0.0 0.0021 18.0 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase TniB PF05621.11 GBG60789.1 - 0.00085 18.8 0.0 0.0078 15.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_29 PF13555.6 GBG60789.1 - 0.0023 17.6 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 GBG60789.1 - 0.0033 16.8 0.0 0.0085 15.4 0.0 1.6 1 1 0 1 1 1 1 Septin AIG1 PF04548.16 GBG60789.1 - 0.0067 15.8 0.0 2.3 7.5 0.0 2.5 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.6 GBG60789.1 - 0.014 15.7 0.1 0.14 12.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GBG60789.1 - 0.015 15.8 0.7 5.2 7.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain GTP_EFTU PF00009.27 GBG60789.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 GBG60789.1 - 0.023 15.2 0.0 0.087 13.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 GBG60789.1 - 0.03 13.5 0.0 0.29 10.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 GBG60789.1 - 0.04 13.6 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pox_A3L PF05288.11 GBG60789.1 - 0.042 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Poxvirus A3L Protein NACHT PF05729.12 GBG60789.1 - 0.063 13.2 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 GBG60789.1 - 0.066 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 GBG60789.1 - 0.083 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 GBG60789.1 - 0.092 12.8 0.1 18 5.4 0.0 3.0 2 0 0 2 2 2 0 Dynamin family Sigma54_activat PF00158.26 GBG60789.1 - 0.093 12.4 0.0 0.44 10.2 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain TsaE PF02367.17 GBG60789.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IIGP PF05049.13 GBG60789.1 - 0.13 11.3 0.0 0.43 9.6 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 GBG60789.1 - 0.14 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase VioE PF18234.1 GBG60790.1 - 0.23 11.6 1.3 0.37 10.9 1.3 1.3 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE DUF5476 PF17570.2 GBG60792.1 - 2.3 8.7 5.1 1 9.8 1.4 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5476) Lyase_catalyt PF09093.11 GBG60793.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Lyase, catalytic VirB3 PF05101.13 GBG60794.1 - 0.0052 17.0 2.3 3.4 8.0 0.1 3.5 2 2 4 6 6 6 4 Type IV secretory pathway, VirB3-like protein Na_H_Exchanger PF00999.21 GBG60795.1 - 1.8e-48 165.3 35.0 2.6e-48 164.7 35.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 GBG60795.1 - 2.9e-07 31.1 3.0 0.00011 22.7 0.0 3.2 3 2 1 4 4 4 2 Universal stress protein family Pyridoxal_deC PF00282.19 GBG60797.1 - 2e-94 316.4 0.0 2.5e-94 316.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GBG60797.1 - 0.0045 16.0 0.0 0.012 14.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V SDA1 PF05285.12 GBG60798.1 - 0.071 12.5 10.8 0.086 12.3 10.8 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG60798.1 - 0.16 10.1 12.4 0.18 10.0 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG60798.1 - 1 7.6 12.9 1.3 7.2 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG60798.1 - 2.7 7.2 19.0 4.1 6.6 19.0 1.2 1 0 0 1 1 1 0 BUD22 Aldedh PF00171.22 GBG60799.1 - 1.2e-45 155.9 0.0 1.5e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SR-25 PF10500.9 GBG60802.1 - 0.025 14.2 27.5 0.046 13.3 27.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LCE PF14672.6 GBG60802.1 - 0.056 14.1 4.2 0.093 13.3 4.1 1.5 1 1 0 1 1 1 0 Late cornified envelope Aldedh PF00171.22 GBG60803.1 - 8.7e-97 324.5 5.8 9.1e-68 228.8 0.5 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family NST1 PF13945.6 GBG60803.1 - 0.18 11.9 0.2 0.26 11.4 0.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator rve PF00665.26 GBG60804.1 - 2.8e-07 30.7 0.0 4.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG60804.1 - 0.0052 16.5 0.2 0.0099 15.6 0.2 1.5 1 0 0 1 1 1 1 Integrase core domain CDC45 PF02724.14 GBG60804.1 - 0.19 10.0 16.1 0.22 9.8 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG60804.1 - 0.22 9.7 22.5 0.27 9.4 22.5 1.0 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 GBG60804.1 - 0.24 11.5 13.9 0.32 11.1 13.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TFIIF_alpha PF05793.12 GBG60804.1 - 0.34 9.5 21.8 0.41 9.2 21.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop53 PF07767.11 GBG60804.1 - 0.5 9.7 26.3 0.73 9.2 26.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BUD22 PF09073.10 GBG60804.1 - 0.64 9.3 24.8 0.81 9.0 24.8 1.0 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 GBG60804.1 - 0.75 9.3 17.5 1 8.9 17.5 1.2 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 GBG60804.1 - 0.77 8.5 9.3 0.85 8.3 9.3 1.1 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.12 GBG60804.1 - 3.4 7.3 19.1 4.5 6.9 19.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG60804.1 - 3.7 6.9 24.5 4.8 6.5 24.5 1.1 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.7 GBG60804.1 - 5.8 4.9 12.1 6.9 4.7 12.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 GBG60804.1 - 6.6 5.4 10.8 7.7 5.2 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2151 PF10221.9 GBG60804.1 - 6.8 5.2 8.1 8.2 4.9 8.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator LAP1C PF05609.12 GBG60804.1 - 8.4 5.4 12.4 9.5 5.2 12.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3381 PF11861.8 GBG60805.1 - 0.032 14.0 8.3 0.062 13.1 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RR_TM4-6 PF06459.12 GBG60805.1 - 0.53 10.1 5.8 0.69 9.7 5.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTPRCAP PF15713.5 GBG60805.1 - 1.9 8.8 8.8 3.3 8.0 8.8 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CENP-N PF05238.13 GBG60805.1 - 2.4 7.4 6.9 4.3 6.5 6.9 1.3 1 1 0 1 1 1 0 Kinetochore protein CHL4 like RT_RNaseH_2 PF17919.1 GBG60806.1 - 1.3e-27 95.7 0.0 3e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60806.1 - 4.9e-23 81.4 0.0 9.4e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60806.1 - 4.6e-14 52.5 0.1 7.7e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG60806.1 - 0.004 16.9 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DDHD PF02862.17 GBG60806.1 - 0.74 9.9 5.0 7.3 6.7 4.0 2.3 2 0 0 2 2 2 0 DDHD domain BUD22 PF09073.10 GBG60806.1 - 1.5 8.1 40.1 0.37 10.1 29.6 2.7 3 0 0 3 3 3 0 BUD22 SpoIIIAH PF12685.7 GBG60806.1 - 4.4 7.1 15.9 14 5.4 11.4 2.8 3 0 0 3 3 3 0 SpoIIIAH-like protein CPSF100_C PF13299.6 GBG60806.1 - 6.4 6.9 16.7 13 6.0 11.0 2.8 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 GBG60806.1 - 9.2 5.6 11.5 18 4.6 9.1 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Imm32 PF15566.6 GBG60807.1 - 0.23 11.3 2.9 3.2 7.6 0.0 2.8 3 0 0 3 3 3 0 Immunity protein 32 DUF659 PF04937.15 GBG60809.1 - 3.8e-26 91.8 0.3 3.8e-26 91.8 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Paf1 PF03985.13 GBG60809.1 - 2 7.3 7.2 3.1 6.7 7.2 1.2 1 0 0 1 1 1 0 Paf1 TFIIA PF03153.13 GBG60809.1 - 2.6 8.0 7.7 3.4 7.5 7.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF948 PF06103.11 GBG60810.1 - 0.36 11.1 16.4 31 4.9 0.2 7.0 6 2 2 8 8 8 0 Bacterial protein of unknown function (DUF948) Matrilin_ccoil PF10393.9 GBG60811.1 - 0.006 16.4 0.3 0.93 9.4 0.0 3.0 3 0 0 3 3 3 2 Trimeric coiled-coil oligomerisation domain of matrilin zf-CCHC PF00098.23 GBG60811.1 - 0.029 14.5 1.2 0.029 14.5 1.2 1.8 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG60812.1 - 4.6e-30 104.8 0.0 8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60812.1 - 8e-17 61.1 0.0 1.7e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60812.1 - 4.5e-15 55.5 0.0 2.6e-14 53.0 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG60812.1 - 0.00013 22.2 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG60812.1 - 0.00031 20.9 0.0 0.00071 19.7 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG60812.1 - 0.0011 19.1 0.0 0.0038 17.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain OapA_N PF08525.11 GBG60813.1 - 0.43 10.6 1.4 0.67 10.0 1.4 1.3 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif CENP-Q PF13094.6 GBG60814.1 - 1.8 8.8 11.0 0.36 11.0 7.1 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RT_RNaseH_2 PF17919.1 GBG60815.1 - 7.8e-33 112.5 0.2 6.5e-32 109.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60815.1 - 1.9e-28 98.8 0.2 3.9e-28 97.8 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60815.1 - 1.5e-23 83.5 0.0 2.9e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60815.1 - 1.5e-18 66.6 0.3 4.7e-18 65.1 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG60815.1 - 0.00015 21.9 0.0 0.00054 20.1 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG60815.1 - 0.00039 20.9 0.0 0.00077 20.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60815.1 - 0.045 14.4 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease HepII_C PF18675.1 GBG60815.1 - 0.16 12.1 0.0 14 5.8 0.0 2.9 2 0 0 2 2 2 0 Heparinase II C-terminal domain RVT_1 PF00078.27 GBG60816.1 - 1.1e-34 119.9 0.7 1.2e-19 70.7 0.1 3.3 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60816.1 - 3.8e-24 84.6 0.0 9.2e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60816.1 - 1.6e-23 83.0 0.1 5.7e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60816.1 - 1.6e-18 66.6 0.2 4.3e-18 65.2 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain SlyX PF04102.12 GBG60816.1 - 0.0085 16.7 0.3 0.0085 16.7 0.3 2.5 3 0 0 3 3 3 1 SlyX zf-H2C2 PF09337.10 GBG60816.1 - 0.069 13.4 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 H2C2 zinc finger RVT_1 PF00078.27 GBG60817.1 - 8.1e-27 94.2 0.1 1.7e-26 93.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60817.1 - 1.2e-25 89.4 0.0 3.4e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60817.1 - 9e-24 83.8 0.0 2.6e-23 82.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60817.1 - 9.7e-10 38.4 0.0 2.6e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60817.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG60817.1 - 0.058 13.7 0.2 0.51 10.7 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein HXXSHH PF07586.11 GBG60817.1 - 0.15 11.6 1.8 7.1 6.1 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1552) ATG16 PF08614.11 GBG60817.1 - 5.1 7.3 7.8 3.1 8.0 0.0 3.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) CarboxypepD_reg PF13620.6 GBG60818.1 - 3.3e-46 155.5 21.3 3.3e-09 36.9 0.2 9.9 8 2 1 9 9 9 6 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 GBG60818.1 - 7.3e-23 80.9 3.4 0.0019 18.4 0.0 9.0 7 2 3 10 10 10 4 SdrD B-like domain DUF2012 PF09430.10 GBG60818.1 - 5.3e-17 62.1 0.0 0.024 14.8 0.0 7.5 7 1 0 7 7 7 3 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 GBG60818.1 - 1e-11 44.7 6.9 0.0014 18.6 0.1 7.9 8 0 0 8 8 8 3 CarboxypepD_reg-like domain SpaA PF17802.1 GBG60818.1 - 5.3e-11 42.7 0.5 0.093 13.1 0.0 6.8 7 1 0 7 7 6 2 Prealbumin-like fold domain fn3_3 PF14686.6 GBG60818.1 - 3.2e-06 26.8 6.0 0.17 11.7 0.0 6.1 7 0 0 7 7 7 2 Polysaccharide lyase family 4, domain II bMG3 PF11974.8 GBG60818.1 - 0.00013 22.0 0.0 0.028 14.4 0.0 3.3 3 0 0 3 3 3 1 Bacterial alpha-2-macroglobulin MG3 domain MetallophosN PF16371.5 GBG60818.1 - 0.0011 19.2 7.5 0.093 13.0 0.2 4.9 5 1 1 6 6 6 1 N terminal of Calcineurin-like phosphoesterase Dioxygenase_C PF00775.21 GBG60818.1 - 0.01 15.3 0.7 4.9 6.6 0.0 4.4 5 1 0 5 5 5 0 Dioxygenase phage_tail_N PF08400.10 GBG60818.1 - 0.015 15.3 1.4 9.2 6.3 0.2 3.5 2 1 1 3 3 3 0 Prophage tail fibre N-terminal DUF4198 PF10670.9 GBG60818.1 - 0.027 14.8 0.0 32 4.8 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4198) fn3 PF00041.21 GBG60818.1 - 0.075 13.4 0.0 2.2 8.7 0.0 3.4 4 0 0 4 4 4 0 Fibronectin type III domain CarboxypepD_reg PF13620.6 GBG60819.1 - 2.5e-46 155.9 21.7 3.3e-09 36.9 0.2 9.9 8 2 1 9 9 9 7 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 GBG60819.1 - 1.3e-23 83.4 0.6 0.0019 18.4 0.0 8.9 8 1 2 10 10 10 4 SdrD B-like domain DUF2012 PF09430.10 GBG60819.1 - 5.8e-17 61.9 0.0 0.024 14.8 0.0 7.5 7 1 0 7 7 7 3 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 GBG60819.1 - 1.1e-11 44.6 6.9 0.0014 18.6 0.1 7.9 8 0 0 8 8 8 3 CarboxypepD_reg-like domain SpaA PF17802.1 GBG60819.1 - 5.2e-11 42.7 0.5 0.093 13.1 0.0 6.8 7 1 0 7 7 6 2 Prealbumin-like fold domain fn3_3 PF14686.6 GBG60819.1 - 3.2e-06 26.8 6.0 0.17 11.7 0.0 6.1 7 0 0 7 7 7 2 Polysaccharide lyase family 4, domain II bMG3 PF11974.8 GBG60819.1 - 0.00013 22.0 0.0 0.028 14.4 0.0 3.3 3 0 0 3 3 3 1 Bacterial alpha-2-macroglobulin MG3 domain MetallophosN PF16371.5 GBG60819.1 - 0.00098 19.3 7.3 0.093 13.0 0.2 4.9 5 1 1 6 6 6 1 N terminal of Calcineurin-like phosphoesterase phage_tail_N PF08400.10 GBG60819.1 - 0.01 15.8 1.2 9.2 6.3 0.2 3.5 2 1 1 3 3 3 0 Prophage tail fibre N-terminal Dioxygenase_C PF00775.21 GBG60819.1 - 0.015 14.7 1.1 4.9 6.6 0.0 4.3 5 1 0 5 5 5 0 Dioxygenase DUF4198 PF10670.9 GBG60819.1 - 0.028 14.8 0.0 32 4.8 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4198) fn3 PF00041.21 GBG60819.1 - 0.074 13.4 0.0 2.2 8.7 0.0 3.4 4 0 0 4 4 4 0 Fibronectin type III domain Retrotrans_gag PF03732.17 GBG60820.1 - 0.011 16.0 0.2 0.071 13.4 0.1 2.3 2 1 0 2 2 2 0 Retrotransposon gag protein NusB PF01029.18 GBG60820.1 - 0.12 12.6 0.5 0.43 10.8 0.1 2.1 3 0 0 3 3 3 0 NusB family gag-asp_proteas PF13975.6 GBG60821.1 - 5.1e-07 30.2 0.1 1.3e-06 28.8 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60821.1 - 5.8e-05 23.7 0.1 0.00014 22.4 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60821.1 - 0.00074 19.3 0.1 0.0013 18.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60821.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG60821.1 - 0.033 14.3 1.2 0.073 13.2 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle ATE_N PF04376.13 GBG60821.1 - 0.17 12.3 0.2 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus Herpes_LMP1 PF05297.11 GBG60822.1 - 0.94 8.6 5.1 2 7.5 5.1 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RVT_1 PF00078.27 GBG60823.1 - 2.4e-52 177.6 0.2 1.8e-29 102.9 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-binding PF00249.31 GBG60823.1 - 4.7e-33 113.1 8.6 3.3e-16 59.2 0.9 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG60823.1 - 1.7e-23 82.6 1.4 7.1e-18 64.6 0.3 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GBG60823.1 - 0.00069 19.5 0.1 0.012 15.5 0.0 2.6 1 1 1 2 2 2 1 Myb DNA-binding like Lipin_mid PF16876.5 GBG60823.1 - 0.0014 18.7 0.1 0.88 9.8 0.0 2.8 2 0 0 2 2 2 2 Lipin/Ned1/Smp2 multi-domain protein middle domain RVP_2 PF08284.11 GBG60823.1 - 0.0043 16.8 0.1 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG60823.1 - 0.013 15.7 17.4 0.02 15.2 0.2 4.6 4 0 0 4 4 4 0 Retrotransposon gag protein DUF4916 PF16262.5 GBG60823.1 - 0.015 14.8 0.1 3.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4916) DUF659 PF04937.15 GBG60824.1 - 3.2e-23 82.3 0.0 5.5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Presenilin PF01080.17 GBG60825.1 - 0.42 9.3 17.7 0.52 9.0 17.7 1.3 1 0 0 1 1 1 0 Presenilin Dapper PF15268.6 GBG60825.1 - 0.42 9.4 13.5 0.47 9.3 13.5 1.1 1 0 0 1 1 1 0 Dapper Suf PF05843.14 GBG60825.1 - 4.4 7.2 11.2 5.7 6.8 11.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Utp14 PF04615.13 GBG60825.1 - 4.7 5.7 23.3 5.2 5.5 23.3 1.1 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 GBG60825.1 - 6.3 5.7 20.3 8.7 5.2 20.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 GBG60825.1 - 9.9 4.6 28.1 10 4.5 28.1 1.1 1 0 0 1 1 1 0 Macoilin family RT_RNaseH_2 PF17919.1 GBG60827.1 - 1.1e-24 86.3 0.0 2.1e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60827.1 - 7.4e-23 80.8 0.0 1.4e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60827.1 - 8.2e-16 58.2 0.0 1.4e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG60827.1 - 0.001 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG60827.1 - 0.0056 16.7 2.8 0.011 15.7 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle ADIP PF11559.8 GBG60827.1 - 0.033 14.3 1.5 0.051 13.7 0.1 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 GBG60827.1 - 0.047 12.6 0.2 0.1 11.5 0.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein gag-asp_proteas PF13975.6 GBG60827.1 - 0.18 12.4 0.0 0.44 11.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF805 PF05656.14 GBG60828.1 - 0.63 10.5 4.6 14 6.1 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF805) NinD PF17466.2 GBG60828.1 - 2.2 8.5 5.2 28 4.9 0.4 2.7 2 0 0 2 2 2 0 Family of unknown function RE_ApaLI PF09499.10 GBG60829.1 - 0.052 13.3 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease zf-CCCH_4 PF18044.1 GBG60832.1 - 3.2e-08 33.2 4.2 6.2e-08 32.3 4.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GBG60832.1 - 9.7e-07 28.7 7.8 1.9e-06 27.8 7.8 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 GBG60832.1 - 1.1e-06 29.3 0.1 2.3e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 GBG60832.1 - 1.2e-06 28.2 2.1 2.2e-06 27.4 2.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GBG60832.1 - 0.021 15.3 2.9 0.044 14.3 2.9 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Tmemb_14 PF03647.13 GBG60834.1 - 5.7e-16 59.0 5.0 1.1e-15 58.2 5.0 1.5 1 0 0 1 1 1 1 Transmembrane proteins 14C Retrotrans_gag PF03732.17 GBG60834.1 - 0.00094 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF3863 PF12979.7 GBG60834.1 - 0.0028 16.5 0.0 0.0042 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3863) zf-CCHC_3 PF13917.6 GBG60834.1 - 0.012 15.5 1.3 0.028 14.4 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4106 PF13388.6 GBG60834.1 - 0.064 12.5 3.1 0.094 11.9 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RCC1 PF00415.18 GBG60835.1 - 2.4e-54 181.7 21.6 1.1e-16 61.2 0.3 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG60835.1 - 1.1e-12 47.4 32.9 0.00015 21.4 0.7 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Mg_chelatase PF01078.21 GBG60835.1 - 0.1 12.0 0.4 6.3 6.1 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TSC21 PF15217.6 GBG60835.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 TSC21 family vATP-synt_E PF01991.18 GBG60837.1 - 1.9e-61 207.0 0.0 2.6e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FoP_duplication PF13865.6 GBG60837.1 - 0.0014 19.1 1.5 1.7 9.3 0.7 2.6 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 THOC7 PF05615.13 GBG60837.1 - 0.067 13.5 11.8 0.11 12.8 11.8 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 HSP70 PF00012.20 GBG60837.1 - 0.27 9.4 7.4 12 3.9 9.2 1.9 2 0 0 2 2 2 0 Hsp70 protein APG6_N PF17675.1 GBG60837.1 - 1 9.9 13.1 1.8 9.1 13.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1283 PF06932.11 GBG60837.1 - 2.6 8.3 5.2 1.6 9.0 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) Cation_ATPase_C PF00689.21 GBG60839.1 - 1.5e-38 132.3 10.7 1.5e-38 132.3 10.7 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GBG60839.1 - 7.6e-34 116.8 0.8 7.6e-34 116.8 0.8 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GBG60839.1 - 1.4e-18 68.0 0.1 1.8e-14 54.5 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GBG60839.1 - 3.2e-11 43.1 0.0 6.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GBG60839.1 - 9.8e-09 35.3 0.0 3.8e-07 30.1 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GBG60839.1 - 1.5e-06 27.7 0.0 3.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 GBG60839.1 - 0.025 15.0 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PRIMA1 PF16101.5 GBG60839.1 - 4.3 7.4 5.1 1.2 9.2 0.8 2.3 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 RVT_1 PF00078.27 GBG60841.1 - 1.4e-21 77.1 0.1 2.3e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60841.1 - 1.2e-09 38.4 0.0 3.3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG60841.1 - 1.1e-06 29.1 0.0 2.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60841.1 - 1.5e-06 28.7 0.0 2.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60841.1 - 3.7e-06 26.7 0.0 7.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60841.1 - 0.00057 19.7 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG60841.1 - 0.0031 17.4 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CRT10 PF08728.10 GBG60842.1 - 0.011 14.0 4.4 0.014 13.6 4.4 1.1 1 0 0 1 1 1 0 CRT10 NPV_P10 PF05531.12 GBG60842.1 - 0.34 11.4 5.1 7.9 7.0 2.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 GBG60842.1 - 2.7 8.2 24.2 0.73 10.1 6.3 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Tweety PF04906.13 GBG60842.1 - 4.3 5.9 7.8 0.1 11.3 1.4 1.5 2 0 0 2 2 2 0 Tweety ZapB PF06005.12 GBG60843.1 - 0.017 15.5 7.6 0.17 12.4 7.6 2.3 1 1 0 1 1 1 0 Cell division protein ZapB LUC7 PF03194.15 GBG60843.1 - 0.02 14.6 1.1 0.024 14.3 1.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Tweety PF04906.13 GBG60843.1 - 0.022 13.4 1.5 0.033 12.8 1.5 1.2 1 0 0 1 1 1 0 Tweety TMF_TATA_bd PF12325.8 GBG60843.1 - 0.036 14.3 4.2 0.14 12.3 3.8 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 GBG60843.1 - 0.038 14.6 3.7 0.61 10.7 1.9 2.2 2 0 0 2 2 2 0 Initiation control protein YabA NPV_P10 PF05531.12 GBG60843.1 - 0.065 13.7 5.1 3.2 8.3 2.6 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 GBG60843.1 - 0.21 11.8 3.1 3.2 8.0 3.1 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 GBG60843.1 - 0.39 11.0 4.3 1.5 9.1 0.8 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain XhlA PF10779.9 GBG60843.1 - 0.56 10.5 3.4 2.3 8.5 0.8 2.9 3 0 0 3 3 3 0 Haemolysin XhlA Fzo_mitofusin PF04799.13 GBG60843.1 - 1.8 8.1 7.0 0.97 9.0 3.3 2.2 2 1 1 3 3 3 0 fzo-like conserved region ATG16 PF08614.11 GBG60843.1 - 2.4 8.3 14.4 0.98 9.6 9.8 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 GBG60845.1 - 3.2 8.5 9.5 0.24 12.1 3.5 2.4 2 0 0 2 2 2 0 SlyX WSD PF15613.6 GBG60848.1 - 2.5e-18 66.4 1.9 2.5e-18 66.4 1.9 3.8 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 GBG60848.1 - 1.4e-15 57.3 0.3 3.2e-15 56.2 0.3 1.6 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 GBG60848.1 - 0.00078 18.9 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WAC_Acf1_DNA_bd PF10537.9 GBG60848.1 - 0.0054 17.2 0.1 0.0054 17.2 0.1 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 GBG60849.1 - 1.9e-18 66.8 1.9 1.9e-18 66.8 1.9 3.5 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 GBG60849.1 - 1e-15 57.8 0.3 2.5e-15 56.5 0.3 1.7 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 GBG60849.1 - 0.00063 19.2 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WAC_Acf1_DNA_bd PF10537.9 GBG60849.1 - 0.0019 18.7 0.7 0.0043 17.5 0.1 2.0 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DAD PF02109.16 GBG60850.1 - 1.2e-30 106.0 0.6 1.5e-30 105.7 0.6 1.2 1 0 0 1 1 1 1 DAD family Response_reg PF00072.24 GBG60851.1 - 3.8e-29 101.1 0.0 4.8e-21 75.0 0.0 2.7 2 1 0 2 2 2 2 Response regulator receiver domain RVT_1 PF00078.27 GBG60851.1 - 5.2e-28 98.1 0.0 1e-27 97.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HisKA PF00512.25 GBG60851.1 - 5.9e-16 58.3 0.0 1.8e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 GBG60851.1 - 3.2e-13 50.2 0.0 6.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RT_RNaseH PF17917.1 GBG60851.1 - 6.3e-11 42.5 0.0 1.2e-09 38.4 0.0 2.4 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60851.1 - 2.3e-10 40.4 0.0 1.1e-07 31.8 0.0 2.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CHASE PF03924.13 GBG60851.1 - 2.9e-09 37.1 0.0 5.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 CHASE domain Asp_protease_2 PF13650.6 GBG60851.1 - 1.4e-08 35.3 0.0 6.1e-08 33.2 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60851.1 - 1.5e-08 34.5 0.0 3.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60851.1 - 1e-06 29.2 0.0 8.7e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60851.1 - 0.00045 20.0 0.0 0.0052 16.6 0.0 2.5 3 0 0 3 3 2 1 Aspartyl protease ADH_zinc_N PF00107.26 GBG60851.1 - 0.027 14.5 0.1 5.1 7.1 0.0 2.8 3 0 0 3 3 2 0 Zinc-binding dehydrogenase Rab_bind PF16704.5 GBG60851.1 - 0.3 11.1 1.7 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Rab binding domain LapA_dom PF06305.11 GBG60851.1 - 5.9 6.8 6.8 42 4.1 1.8 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Myb_DNA-bind_4 PF13837.6 GBG60852.1 - 6.8e-07 29.6 3.0 1.2e-06 28.8 3.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Merozoite_SPAM PF07133.11 GBG60853.1 - 0.0046 17.0 14.9 0.0066 16.5 14.9 1.1 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) CDC45 PF02724.14 GBG60853.1 - 0.012 14.0 9.3 0.013 13.8 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GBG60853.1 - 0.84 8.0 14.1 1.1 7.6 14.1 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG60853.1 - 1.6 8.1 14.8 1.9 7.8 14.8 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG60853.1 - 1.9 7.2 5.6 2.4 6.8 5.6 1.1 1 0 0 1 1 1 0 Presenilin HGTP_anticodon2 PF12745.7 GBG60853.1 - 2 7.9 6.4 2.8 7.4 6.4 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Nop14 PF04147.12 GBG60853.1 - 2.5 6.2 14.9 3.3 5.8 14.9 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 GBG60853.1 - 3.2 6.2 5.4 4.1 5.8 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RR_TM4-6 PF06459.12 GBG60853.1 - 4.7 6.9 8.1 7.3 6.3 8.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 GBG60853.1 - 6.4 5.2 18.3 8.2 4.9 18.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Paf1 PF03985.13 GBG60853.1 - 7.4 5.4 15.4 10 5.0 15.4 1.1 1 0 0 1 1 1 0 Paf1 DUF659 PF04937.15 GBG60854.1 - 3.7e-17 62.6 0.0 5.5e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG60856.1 - 1.5e-23 83.0 0.0 3.1e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60856.1 - 3.4e-23 81.6 0.0 6.6e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60856.1 - 6.7e-16 58.5 0.1 5e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG60857.1 - 8.7e-25 87.5 0.1 1.6e-24 86.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG60857.1 - 2.1e-08 34.4 0.0 5.9e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain EP400_N PF15790.5 GBG60857.1 - 0.18 10.6 5.1 0.26 10.1 5.1 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Rrn6 PF10214.9 GBG60857.1 - 3.4 6.1 9.0 4.7 5.6 9.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Nse4_C PF08743.10 GBG60858.1 - 1.5e-22 79.7 0.0 4e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal DUF659 PF04937.15 GBG60859.1 - 2.2e-33 115.3 0.2 3.5e-33 114.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60859.1 - 3.8e-08 33.0 0.1 8.9e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Plexin_cytopl PF08337.12 GBG60859.1 - 1.9 7.1 4.9 2.4 6.7 3.9 1.5 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Methyltransf_11 PF08241.12 GBG60860.1 - 1.3e-11 45.0 0.0 3.2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG60860.1 - 1.1e-08 35.6 0.0 3e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG60860.1 - 0.00086 20.0 0.0 0.0025 18.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG60860.1 - 0.0025 17.7 0.0 0.0074 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG60860.1 - 0.0047 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Chromo PF00385.24 GBG60861.1 - 8.5e-05 22.4 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG60861.1 - 0.003 17.8 2.1 0.0032 17.7 0.2 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein PAN_4 PF14295.6 GBG60862.1 - 0.00049 19.9 1.7 0.00084 19.2 1.7 1.3 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 GBG60862.1 - 0.029 14.3 2.0 0.035 14.1 2.0 1.3 1 0 0 1 1 1 0 PAN domain DDE_Tnp_4 PF13359.6 GBG60864.1 - 2.2e-07 30.7 0.1 4.8e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60864.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG60864.1 - 0.039 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Transposase DDE domain RSN1_7TM PF02714.15 GBG60865.1 - 1.1e-58 198.8 18.4 1.8e-58 198.1 18.4 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GBG60865.1 - 7.3e-25 88.2 0.0 1e-17 64.9 0.0 2.9 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GBG60865.1 - 4.2e-16 59.1 4.8 1.1e-15 57.8 4.8 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport Sigma70_ner PF04546.13 GBG60865.1 - 0.016 15.1 0.1 0.016 15.1 0.1 3.5 5 0 0 5 5 5 0 Sigma-70, non-essential region RVT_1 PF00078.27 GBG60866.1 - 1.5e-27 96.6 0.0 2.1e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG60866.1 - 0.00015 22.2 0.0 0.00028 21.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60866.1 - 0.00016 22.3 0.0 0.0003 21.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG60866.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60866.1 - 0.0054 16.5 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RRM_1 PF00076.22 GBG60867.1 - 0.0015 18.3 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHIPEP PF00771.20 GBG60867.1 - 0.002 16.7 1.4 0.0025 16.4 1.4 1.1 1 0 0 1 1 1 1 FHIPEP family TFIIA PF03153.13 GBG60867.1 - 0.013 15.5 11.3 0.014 15.4 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 GBG60867.1 - 0.055 13.9 5.7 0.065 13.7 5.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 GBG60867.1 - 0.094 12.3 10.3 0.13 11.8 10.3 1.3 1 0 0 1 1 1 0 Spt20 family AAA_11 PF13086.6 GBG60867.1 - 3.3 7.4 10.9 4.6 6.9 10.9 1.2 1 0 0 1 1 1 0 AAA domain EIIBC-GUT_N PF03612.14 GBG60867.1 - 6.3 6.5 8.4 3.7 7.3 1.7 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus KBP_C PF12309.8 GBG60868.1 - 2.4e-58 198.4 3.7 7.8e-58 196.7 1.2 2.7 2 1 0 2 2 2 1 KIF-1 binding protein C terminal TPR_7 PF13176.6 GBG60868.1 - 8.9e-05 22.3 6.3 0.062 13.3 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG60868.1 - 0.0025 17.6 7.2 0.011 15.5 0.3 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 GBG60868.1 - 0.0028 17.4 1.6 2.3 7.9 0.2 2.6 2 0 0 2 2 2 2 26S proteasome subunit RPN7 TPR_2 PF07719.17 GBG60868.1 - 0.016 15.3 8.8 1.1 9.6 0.4 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG60868.1 - 0.035 14.0 9.3 1.2 9.1 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ENTH PF01417.20 GBG60868.1 - 0.072 13.1 0.0 0.26 11.3 0.0 2.0 1 0 0 1 1 1 0 ENTH domain TPR_17 PF13431.6 GBG60868.1 - 0.073 13.5 0.6 4.7 7.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG60868.1 - 0.12 12.7 6.5 5.2 7.5 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG60868.1 - 0.12 12.7 17.6 3.3 8.1 3.2 5.9 4 2 2 6 6 6 0 Tetratricopeptide repeat Taxilin PF09728.9 GBG60869.1 - 1.3e-80 270.9 61.1 1.3e-80 270.9 61.1 2.3 1 1 1 2 2 2 1 Myosin-like coiled-coil protein Adenylsucc_synt PF00709.21 GBG60870.1 - 8.7e-174 578.3 0.0 1.2e-173 577.9 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase RVT_1 PF00078.27 GBG60871.1 - 5.1e-31 107.9 0.0 8.2e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG60871.1 - 1.1e-12 47.6 0.0 2.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain GSH_synth_ATP PF03917.17 GBG60872.1 - 3.4e-110 368.4 0.0 2e-54 184.8 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain RT_RNaseH_2 PF17919.1 GBG60873.1 - 1.6e-26 92.3 0.0 2.6e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60873.1 - 1.8e-22 79.6 0.0 3.2e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60873.1 - 2.6e-07 30.4 0.1 4.3e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PEPcase PF00311.17 GBG60875.1 - 1.3e-279 929.7 0.0 1.6e-279 929.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 GBG60875.1 - 1.7e-06 26.8 0.0 3.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Med9 PF07544.13 GBG60875.1 - 0.67 10.1 2.7 23 5.2 0.0 3.6 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Pkinase_Tyr PF07714.17 GBG60876.1 - 1.5e-20 73.6 0.0 1.4e-16 60.6 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 GBG60876.1 - 1.1e-17 64.3 0.0 2.3e-07 30.4 0.0 3.9 4 0 0 4 4 4 3 Protein kinase domain SGL PF08450.12 GBG60876.1 - 7.8e-06 25.7 0.0 0.00021 21.0 0.0 3.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region APH PF01636.23 GBG60876.1 - 0.088 12.7 0.4 1.1 9.2 0.4 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3523 PF12037.8 GBG60877.1 - 2.6e-26 92.6 5.5 3.4e-26 92.2 5.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) Cytochrom_C1 PF02167.15 GBG60877.1 - 0.013 15.2 0.2 0.016 14.9 0.2 1.2 1 0 0 1 1 1 0 Cytochrome C1 family Trp_repressor PF01371.19 GBG60877.1 - 0.041 14.0 2.0 0.059 13.5 2.0 1.2 1 0 0 1 1 1 0 Trp repressor protein Peptidase_M91 PF14891.6 GBG60877.1 - 0.057 13.7 3.2 0.056 13.8 2.1 1.4 1 1 0 1 1 1 0 Effector protein RT_RNaseH_2 PF17919.1 GBG60878.1 - 4.2e-33 113.4 0.0 1.1e-32 112.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60878.1 - 4e-31 107.4 0.1 6.2e-30 103.6 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60878.1 - 4.1e-05 23.6 0.2 0.00019 21.5 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Pkinase_Tyr PF07714.17 GBG60880.1 - 4.6e-44 150.6 0.0 6e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG60880.1 - 7.2e-31 107.5 0.0 9.9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GBG60880.1 - 1.2e-06 28.1 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Sporozoite_P67 PF05642.11 GBG60880.1 - 9.6 4.1 5.4 13 3.8 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RVT_1 PF00078.27 GBG60881.1 - 3.5e-16 59.4 0.1 5.2e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG60881.1 - 9.8e-08 32.5 0.0 2.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60881.1 - 6.2e-07 29.9 0.0 1.3e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG60881.1 - 7.3e-06 25.8 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG60881.1 - 0.0003 20.6 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Abhydrolase_6 PF12697.7 GBG60881.1 - 0.00047 20.8 0.2 0.00095 19.8 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG60881.1 - 0.0019 17.9 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG60881.1 - 0.015 14.6 0.0 0.038 13.2 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GBG60881.1 - 0.036 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.20 GBG60882.1 - 1.3e-07 31.5 0.1 2.6e-07 30.5 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG60882.1 - 4.4e-05 24.2 0.1 0.00012 22.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG60882.1 - 0.0045 16.3 0.0 0.0096 15.2 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF4168 PF13767.6 GBG60882.1 - 0.18 13.0 1.2 0.28 12.4 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) Noelin-1 PF12308.8 GBG60882.1 - 2 8.4 4.9 4.9 7.2 0.8 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein RVT_1 PF00078.27 GBG60883.1 - 1.3e-27 96.7 0.0 2.4e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60883.1 - 6.9e-27 93.4 0.0 1.9e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60883.1 - 6.1e-25 87.5 0.0 1.7e-24 86.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG60883.1 - 0.00071 19.8 2.3 0.0029 17.8 0.1 3.2 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG60883.1 - 0.0026 17.5 0.0 0.044 13.6 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60883.1 - 0.047 14.3 0.0 3.4 8.4 0.0 2.8 1 1 1 2 2 2 0 Aspartyl protease Asp_protease PF09668.10 GBG60883.1 - 0.093 12.5 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG60883.1 - 0.16 12.6 0.0 4.4 7.9 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease NPV_P10 PF05531.12 GBG60883.1 - 0.62 10.6 3.0 0.97 9.9 0.2 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Retrotrans_gag PF03732.17 GBG60884.1 - 0.0007 19.8 0.2 0.0007 19.8 0.2 3.4 3 2 0 3 3 3 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG60884.1 - 0.0076 16.7 0.3 0.26 11.8 0.1 3.0 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF3006 PF11213.8 GBG60884.1 - 0.23 11.7 1.5 0.74 10.1 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) PIEZO PF15917.5 GBG60884.1 - 9.5 5.6 9.4 5 6.5 7.0 1.7 2 0 0 2 2 2 0 Piezo RVT_1 PF00078.27 GBG60885.1 - 1.4e-42 145.7 0.2 8.5e-32 110.5 0.1 2.8 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60885.1 - 7.1e-30 103.0 0.0 3.4e-29 100.8 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60885.1 - 9.1e-28 96.6 0.0 2.4e-27 95.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60885.1 - 3.9e-15 55.7 0.1 9.2e-15 54.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF4392 PF14336.6 GBG60885.1 - 2.4e-05 23.9 0.2 0.27 10.6 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4392) RVP_2 PF08284.11 GBG60885.1 - 0.0045 16.8 0.0 4 7.2 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG60885.1 - 0.052 13.8 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger SpoOE-like PF09388.10 GBG60885.1 - 0.25 11.3 2.4 15 5.6 0.1 2.8 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Sirohm_synth_M PF14824.6 GBG60885.1 - 0.3 10.6 1.1 19 4.8 0.1 2.9 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central PA26 PF04636.13 GBG60885.1 - 2.6 6.9 7.7 4.9 6.0 7.7 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Cas_DxTHG PF09455.10 GBG60885.1 - 2.8 7.5 10.4 20 4.7 0.0 3.8 4 0 0 4 4 4 0 CRISPR-associated (Cas) DxTHG family Membralin PF09746.9 GBG60885.1 - 3.7 6.5 9.8 2 7.3 7.1 1.8 2 0 0 2 2 2 0 Tumour-associated protein P5CR_dimer PF14748.6 GBG60886.1 - 7.5e-43 145.0 1.5 1.8e-42 143.8 1.5 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GBG60886.1 - 3.1e-13 50.1 0.1 7.7e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 GBG60886.1 - 0.00047 20.0 0.1 0.001 18.9 0.1 1.5 1 0 0 1 1 1 1 Rossmann-like domain SOG2 PF10428.9 GBG60888.1 - 5.8 6.0 11.2 8.4 5.5 11.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SpoIIIAH PF12685.7 GBG60889.1 - 0.93 9.3 14.9 0.98 9.2 14.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 GBG60889.1 - 1.7 6.8 42.7 2.4 6.3 42.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 GBG60889.1 - 2 7.8 53.2 3.3 7.0 53.2 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Apt1 PF10351.9 GBG60889.1 - 2.8 6.7 13.0 3.1 6.6 13.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain HD_4 PF13328.6 GBG60892.1 - 2.4e-46 157.3 0.6 3.9e-46 156.6 0.6 1.3 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 GBG60892.1 - 1.1e-33 116.0 0.0 1.6e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD PF01966.22 GBG60892.1 - 0.00084 19.6 0.1 0.0043 17.3 0.2 2.1 2 0 0 2 2 2 1 HD domain DNA_pol3_gamma3 PF12169.8 GBG60892.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III CBS PF00571.28 GBG60893.1 - 4.2e-26 91.1 3.8 2e-13 50.5 0.1 2.3 2 0 0 2 2 2 2 CBS domain Macoilin PF09726.9 GBG60893.1 - 0.14 10.6 6.9 0.17 10.4 6.9 1.0 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 GBG60893.1 - 0.15 11.5 8.6 0.24 10.8 8.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Corona_nucleoca PF00937.18 GBG60893.1 - 0.43 9.6 9.1 0.72 8.8 9.1 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Myb_DNA-bind_4 PF13837.6 GBG60894.1 - 1.7e-05 25.1 0.2 0.0004 20.7 0.1 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG60896.1 - 9.6e-32 109.8 0.0 1.1e-30 106.5 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG60896.1 - 1.4e-12 47.6 0.0 2.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG60896.1 - 0.00013 21.7 0.6 2 8.0 0.1 3.4 3 1 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG60896.1 - 0.058 13.8 0.1 0.57 10.6 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain AOX PF01786.17 GBG60897.1 - 6.7e-36 123.9 1.5 9.6e-36 123.4 1.5 1.2 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 GBG60897.1 - 0.00044 20.1 0.1 0.0012 18.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 HAD_SAK_1 PF10307.9 GBG60897.1 - 0.0045 16.8 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins NUDIX PF00293.28 GBG60898.1 - 2.1e-12 47.2 0.0 5.8e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain MKRN1_C PF15815.5 GBG60898.1 - 0.099 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal Ax_dynein_light PF10211.9 GBG60898.1 - 0.62 10.0 12.3 7.3 6.5 11.5 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Topo_Zn_Ribbon PF08272.11 GBG60899.1 - 0.089 12.5 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like MCR_alpha_N PF02745.15 GBG60900.1 - 0.11 11.9 2.0 1.6 8.0 0.7 2.2 1 1 1 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain gag-asp_proteas PF13975.6 GBG60901.1 - 1.2e-06 28.9 0.0 3.3e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60901.1 - 0.00015 22.3 0.0 0.00042 20.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG60901.1 - 0.00023 20.9 0.1 0.00035 20.3 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG60901.1 - 0.018 14.7 0.3 0.033 13.8 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVP_2 PF08284.11 GBG60901.1 - 0.05 13.4 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG60902.1 - 0.0002 21.6 1.4 0.00029 21.2 1.4 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG60904.1 - 2.6e-22 78.7 0.0 4.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60904.1 - 8.7e-22 77.4 0.0 1.5e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60904.1 - 4.5e-19 68.3 0.1 1.2e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG60904.1 - 1.5e-16 60.6 0.1 8.1e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG60904.1 - 0.00065 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger APG17 PF04108.12 GBG60904.1 - 0.032 13.4 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 RVT_1 PF00078.27 GBG60905.1 - 1.2e-28 100.1 0.0 1.9e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60905.1 - 1.2e-15 57.4 0.1 2.3e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG60905.1 - 0.00015 21.9 0.1 0.00045 20.4 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RabGAP-TBC PF00566.18 GBG60906.1 - 3.1e-48 164.3 0.3 5e-48 163.6 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SLAIN PF15301.6 GBG60906.1 - 0.026 13.8 3.0 0.043 13.1 3.0 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family DUF3246 PF11596.8 GBG60906.1 - 0.19 11.1 3.9 0.34 10.3 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) FAM176 PF14851.6 GBG60906.1 - 0.32 10.6 1.5 0.62 9.7 1.5 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 GBG60906.1 - 2.9 7.1 5.9 5.4 6.3 5.9 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GBG60906.1 - 7.4 6.2 12.2 13 5.5 12.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAD_binding_3 PF01494.19 GBG60907.1 - 0.042 13.1 0.5 0.062 12.5 0.2 1.4 1 1 1 2 2 2 0 FAD binding domain TrkA_C PF02080.21 GBG60912.1 - 0.0065 16.3 0.0 0.7 9.8 0.0 2.5 2 0 0 2 2 2 2 TrkA-C domain Nop14 PF04147.12 GBG60912.1 - 1.2 7.3 33.3 1.8 6.7 33.3 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.23 GBG60913.1 - 7.3e-06 25.8 2.1 1.4e-05 24.9 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG60913.1 - 0.00045 20.0 1.8 0.00092 19.0 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle SH3_15 PF18346.1 GBG60914.1 - 1.5e-104 342.3 47.7 1.5e-15 57.2 0.7 13.1 7 5 3 10 10 10 10 Mind bomb SH3 repeat domain Ank_2 PF12796.7 GBG60914.1 - 5.1e-45 152.0 1.2 9.3e-15 55.0 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG60914.1 - 1.8e-40 136.8 0.1 7.1e-09 36.0 0.0 7.1 4 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 GBG60914.1 - 8.8e-33 111.3 2.0 5.4e-05 23.5 0.0 9.4 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 GBG60914.1 - 4.4e-31 106.5 4.1 3.4e-07 30.4 0.1 7.0 5 2 2 7 7 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG60914.1 - 3.4e-28 94.6 0.7 0.00031 21.0 0.0 9.7 11 0 0 11 11 9 4 Ankyrin repeat Pkinase PF00069.25 GBG60914.1 - 8.9e-25 87.5 0.0 1.5e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG60914.1 - 8.8e-23 80.9 0.0 2.1e-21 76.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase zf-RING_UBOX PF13445.6 GBG60914.1 - 6.1e-09 35.8 5.5 1.5e-08 34.5 5.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GBG60914.1 - 6.5e-08 32.8 8.9 6.5e-08 32.8 8.9 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG60914.1 - 4e-07 29.9 8.4 1.2e-06 28.4 8.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG60914.1 - 2.5e-06 27.3 8.8 7.1e-06 25.8 8.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG60914.1 - 3.3e-06 27.2 7.9 8.5e-06 25.8 7.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING BPL_C PF02237.17 GBG60914.1 - 1.2e-05 25.1 0.5 0.0019 18.0 0.0 4.6 3 0 0 3 3 2 1 Biotin protein ligase C terminal domain zf-C3HC4_3 PF13920.6 GBG60914.1 - 5.3e-05 23.0 7.1 0.00014 21.6 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) tRNA_anti-codon PF01336.25 GBG60914.1 - 0.00076 19.4 0.6 2.3 8.2 0.0 4.4 3 1 1 4 4 3 1 OB-fold nucleic acid binding domain zf-C3HC4_2 PF13923.6 GBG60914.1 - 0.0062 16.4 9.8 0.02 14.8 9.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 GBG60914.1 - 0.0084 15.9 7.3 0.02 14.7 7.3 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Tmemb_55A PF09788.9 GBG60914.1 - 0.011 14.9 1.6 0.019 14.0 1.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A Prok-RING_4 PF14447.6 GBG60914.1 - 0.014 15.3 6.9 0.037 13.9 6.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF3126 PF11324.8 GBG60914.1 - 0.025 14.4 0.2 4.1 7.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3126) Baculo_IE-1 PF05290.11 GBG60914.1 - 0.025 14.5 1.9 0.052 13.5 1.9 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_11 PF17123.5 GBG60914.1 - 0.066 13.0 3.7 0.15 11.9 2.4 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 GBG60914.1 - 0.087 12.9 5.3 0.28 11.3 3.8 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Kinase-like PF14531.6 GBG60914.1 - 0.11 11.8 0.0 0.86 8.9 0.0 2.1 1 1 0 1 1 1 0 Kinase-like NPCBM_assoc PF10633.9 GBG60914.1 - 0.37 11.1 8.1 33 4.8 0.1 5.3 5 0 0 5 5 5 0 NPCBM-associated, NEW3 domain of alpha-galactosidase zf-RING_10 PF16685.5 GBG60914.1 - 1.6 8.9 4.8 4.1 7.6 4.8 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 GBG60914.1 - 1.8 8.7 5.9 5.3 7.2 5.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 GBG60914.1 - 2 8.8 8.5 1.9 8.8 6.4 2.2 2 0 0 2 2 1 0 RING-H2 zinc finger domain Tmemb_14 PF03647.13 GBG60915.1 - 1.2e-18 67.6 16.0 3.2e-18 66.2 16.0 1.7 1 0 0 1 1 1 1 Transmembrane proteins 14C RT_RNaseH_2 PF17919.1 GBG60916.1 - 8.8e-28 96.3 0.0 1.3e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60916.1 - 4.8e-26 91.1 0.0 7e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FRQ PF09421.10 GBG60916.1 - 1.5 6.7 6.4 2 6.4 6.4 1.1 1 0 0 1 1 1 0 Frequency clock protein DUF4746 PF15928.5 GBG60916.1 - 1.7 8.0 11.2 2.6 7.4 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Fucokinase PF07959.12 GBG60917.1 - 0.075 12.0 0.0 0.08 11.9 0.0 1.0 1 0 0 1 1 1 0 L-fucokinase DUF2838 PF10998.8 GBG60918.1 - 7.4e-40 135.7 10.9 1.7e-39 134.5 10.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) RT_RNaseH PF17917.1 GBG60919.1 - 1e-28 99.6 0.0 2.7e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60919.1 - 1.4e-25 89.2 0.0 4.6e-25 87.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60919.1 - 8.7e-19 67.4 0.4 2.1e-18 66.2 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG60919.1 - 0.023 15.0 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Ribosomal_S17_N PF16205.5 GBG60920.1 - 2e-33 114.5 0.5 4.2e-33 113.5 0.5 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 GBG60920.1 - 1.2e-26 92.6 0.7 1.7e-26 92.1 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 RVT_1 PF00078.27 GBG60921.1 - 1.1e-34 119.9 0.1 2.1e-34 119.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60921.1 - 6.7e-30 103.1 0.0 1.8e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60921.1 - 3.8e-28 97.9 0.1 7.5e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG60921.1 - 0.16 11.5 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CTK3 PF12243.8 GBG60922.1 - 1.9e-10 40.8 0.0 3.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 GBG60922.1 - 1.3e-07 32.4 0.0 4.1e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. ATP_bind_1 PF03029.17 GBG60923.1 - 6.1e-93 311.0 0.1 6.9e-93 310.9 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 GBG60923.1 - 0.00015 21.7 0.0 0.00022 21.1 0.0 1.4 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 GBG60923.1 - 0.0032 18.0 0.0 0.0084 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 GBG60923.1 - 0.011 15.8 0.0 0.014 15.4 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 GBG60923.1 - 0.011 16.1 0.0 0.015 15.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GBG60923.1 - 0.018 15.3 0.0 0.041 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GBG60923.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GBG60923.1 - 0.025 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 GBG60923.1 - 0.048 13.6 0.1 14 5.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 GBG60923.1 - 0.052 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 GBG60923.1 - 0.069 12.7 0.0 0.19 11.3 0.0 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 GBG60923.1 - 0.081 13.4 0.1 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GBG60923.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG60923.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 GBG60923.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.27 GBG60923.1 - 0.16 11.5 0.0 7.3 6.1 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CSN8_PSD8_EIF3K PF10075.9 GBG60924.1 - 2.4e-15 56.7 0.0 4.6e-15 55.9 0.0 1.4 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Prefoldin_2 PF01920.20 GBG60925.1 - 7.1e-05 22.7 0.2 8.9e-05 22.4 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4994 PF16385.5 GBG60925.1 - 0.054 13.4 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF572 PF04502.13 GBG60926.1 - 5.7e-60 203.7 0.0 7.2e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) HEAT_2 PF13646.6 GBG60927.1 - 0.0011 19.4 6.1 0.46 10.9 2.3 3.5 2 1 1 3 3 3 2 HEAT repeats DIOX_N PF14226.6 GBG60928.1 - 6.1e-32 110.8 0.0 8.9e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GBG60928.1 - 4.4e-27 94.5 0.0 1e-26 93.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TMF_TATA_bd PF12325.8 GBG60929.1 - 4e-30 104.4 6.6 4e-30 104.4 6.6 6.2 2 1 2 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 GBG60929.1 - 2.3e-14 53.1 9.4 2.3e-14 53.1 9.4 7.9 4 3 4 8 8 8 2 TATA element modulatory factor 1 DNA binding HMMR_N PF15905.5 GBG60929.1 - 0.0036 16.8 36.7 0.0058 16.2 22.1 5.0 3 2 2 5 5 5 2 Hyaluronan mediated motility receptor N-terminal SUIM_assoc PF16619.5 GBG60929.1 - 1 9.5 14.8 0.57 10.3 10.0 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF812 PF05667.11 GBG60929.1 - 2.7 6.7 72.4 0.077 11.9 22.6 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF812) tRNA_bind PF01588.20 GBG60930.1 - 2.6e-30 104.4 0.0 4.4e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Thioredoxin PF00085.20 GBG60932.1 - 1.2e-30 105.6 0.0 1.4e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG60932.1 - 6.1e-05 23.4 0.1 0.00042 20.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG60932.1 - 0.00031 21.0 0.0 0.00076 19.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GBG60932.1 - 0.07 13.3 0.1 0.13 12.5 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like DUF5508 PF17621.2 GBG60932.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5508) Thioredoxin_9 PF14595.6 GBG60932.1 - 0.16 11.7 0.1 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin Kinesin PF00225.23 GBG60933.1 - 2.7e-95 319.1 0.4 4.7e-95 318.3 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG60933.1 - 1.1e-21 77.3 0.0 3e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Atg14 PF10186.9 GBG60933.1 - 0.0074 15.4 5.1 0.016 14.3 5.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Sox_N PF12444.8 GBG60933.1 - 0.03 15.4 1.1 0.16 13.1 0.0 2.7 2 0 0 2 2 2 0 Sox developmental protein N terminal Zot PF05707.12 GBG60933.1 - 0.082 12.5 0.0 9.1 5.9 0.0 3.0 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) zf-C4H2 PF10146.9 GBG60933.1 - 0.35 11.2 4.7 1.2 9.4 4.7 1.9 1 0 0 1 1 1 0 Zinc finger-containing protein Acetyltransf_11 PF13720.6 GBG60933.1 - 0.68 10.4 3.3 15 6.1 0.0 3.5 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Fib_alpha PF08702.10 GBG60933.1 - 6.1 7.0 8.8 4.5 7.5 4.4 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family PRKG1_interact PF15898.5 GBG60933.1 - 7.3 7.6 11.8 19 6.2 9.4 3.0 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 GBG60933.1 - 7.5 7.3 7.5 20 5.9 4.9 2.9 2 1 1 3 3 3 0 Initiation control protein YabA Thioredoxin PF00085.20 GBG60934.1 - 7.1e-31 106.3 0.0 8.5e-31 106.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG60934.1 - 0.00023 21.6 0.1 0.0012 19.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG60934.1 - 0.00062 20.1 0.0 0.0015 18.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 GBG60934.1 - 0.019 14.9 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 GBG60934.1 - 0.023 14.5 0.1 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 GBG60934.1 - 0.045 13.8 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain OST3_OST6 PF04756.13 GBG60934.1 - 0.093 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Asp_protease_2 PF13650.6 GBG60935.1 - 0.0024 18.5 0.0 0.0064 17.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60935.1 - 0.017 15.7 0.0 0.045 14.3 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SOG2 PF10428.9 GBG60935.1 - 0.64 9.2 8.6 0.25 10.5 0.6 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein Pep_deformylase PF01327.21 GBG60935.1 - 0.76 9.4 4.5 0.45 10.1 2.0 1.8 2 0 0 2 2 2 0 Polypeptide deformylase Presenilin PF01080.17 GBG60935.1 - 8.1 5.1 11.5 1.4 7.6 1.8 2.4 2 0 0 2 2 2 0 Presenilin cNMP_binding PF00027.29 GBG60937.1 - 0.17 11.9 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Anth_synt_I_N PF04715.13 GBG60938.1 - 0.016 15.5 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RT_RNaseH_2 PF17919.1 GBG60939.1 - 1.7e-29 101.8 0.0 3.7e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60939.1 - 2.1e-27 95.4 0.0 4.9e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PHD PF00628.29 GBG60939.1 - 0.0058 16.5 4.2 0.0058 16.5 4.2 4.8 4 1 1 5 5 5 3 PHD-finger zf-RING_2 PF13639.6 GBG60939.1 - 0.02 15.2 4.7 0.02 15.2 4.7 4.3 3 1 1 4 4 4 0 Ring finger domain RVT_1 PF00078.27 GBG60939.1 - 0.051 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-HC5HC2H PF13771.6 GBG60939.1 - 0.099 12.9 15.6 2.1 8.6 0.7 3.8 1 1 2 3 3 3 0 PHD-like zinc-binding domain zf-rbx1 PF12678.7 GBG60939.1 - 0.47 10.8 9.5 0.56 10.5 0.2 3.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain FANCL_C PF11793.8 GBG60939.1 - 0.99 9.6 17.2 0.038 14.2 5.0 3.4 2 1 1 3 3 3 0 FANCL C-terminal domain DUF1936 PF09151.10 GBG60939.1 - 1.5 8.8 5.8 0.18 11.7 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) SDA1 PF05285.12 GBG60941.1 - 4.5 6.6 21.4 5.8 6.2 21.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG60941.1 - 5.3 5.1 19.2 9 4.4 19.2 1.3 1 0 0 1 1 1 0 Nop14-like family SID-1_RNA_chan PF13965.6 GBG60942.1 - 0.12 10.7 0.8 0.15 10.4 0.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SNN_linker PF09050.10 GBG60942.1 - 1.7 8.5 5.7 2.4 8.0 0.7 2.3 2 0 0 2 2 2 0 Stannin unstructured linker RNAse_A_bac PF18431.1 GBG60943.1 - 3.6 8.6 5.5 30 5.6 1.5 3.2 3 0 0 3 3 3 0 Bacterial CdiA-CT RNAse A domain Alpha_L_fucos PF01120.17 GBG60946.1 - 2.6e-18 66.6 0.0 4.4e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 GBG60946.1 - 2.3e-08 34.2 0.3 7.4e-08 32.6 0.0 2.0 2 1 0 2 2 2 1 F5/8 type C domain SUIM_assoc PF16619.5 GBG60947.1 - 0.034 14.2 0.2 0.088 12.9 0.2 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SF1-HH PF16275.5 GBG60949.1 - 6.2e-20 71.6 0.1 1.7e-19 70.2 0.1 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 GBG60949.1 - 7.8e-05 22.4 0.2 0.00018 21.2 0.2 1.5 1 0 0 1 1 1 1 KH domain SF1-HH PF16275.5 GBG60950.1 - 6.2e-20 71.6 0.1 1.7e-19 70.2 0.1 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 GBG60950.1 - 1.6e-05 24.7 0.2 3.4e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 KH domain SDA1 PF05285.12 GBG60951.1 - 0.018 14.4 25.6 0.019 14.4 25.6 1.2 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.13 GBG60951.1 - 0.38 9.5 5.1 0.4 9.4 5.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BUD22 PF09073.10 GBG60951.1 - 0.39 10.0 19.1 0.37 10.1 19.1 1.2 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 GBG60951.1 - 0.43 9.5 3.9 0.4 9.6 3.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 GBG60951.1 - 0.99 8.1 7.8 0.93 8.2 7.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Drc1-Sld2 PF11719.8 GBG60951.1 - 1.3 8.5 13.4 1.5 8.3 13.4 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein HABP4_PAI-RBP1 PF04774.15 GBG60951.1 - 2.9 8.7 30.5 0.47 11.3 26.6 1.7 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Gly-rich_Ago1 PF12764.7 GBG60951.1 - 3 8.7 4.6 4.1 8.3 4.6 1.3 1 0 0 1 1 1 0 Glycine-rich region of argonaut RT_RNaseH PF17917.1 GBG60952.1 - 5.8e-22 78.0 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60952.1 - 2.5e-21 75.6 0.0 5.7e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60952.1 - 1.4e-09 37.8 0.0 2.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-rbx1 PF12678.7 GBG60953.1 - 1.5e-25 89.3 12.7 2e-25 88.8 12.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GBG60953.1 - 2e-18 66.2 10.0 2.5e-18 65.9 10.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 GBG60953.1 - 9.1e-07 29.1 8.2 9.1e-07 29.1 8.2 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 GBG60953.1 - 0.00096 19.0 12.1 0.02 14.8 12.1 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG60953.1 - 0.0017 18.1 14.4 0.0032 17.3 9.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG60953.1 - 0.12 12.2 14.9 11 5.9 14.9 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 GBG60953.1 - 0.17 11.8 10.7 0.57 10.1 4.4 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GBG60953.1 - 0.32 10.7 15.1 0.058 13.0 5.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 GBG60953.1 - 0.38 10.8 7.9 1.4 9.0 7.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 GBG60953.1 - 0.5 10.6 9.5 2.7 8.2 9.7 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 GBG60953.1 - 6.4 6.8 12.5 58 3.8 12.5 2.5 1 1 0 1 1 1 0 zinc-RING finger domain CPSase_L_D2 PF02786.17 GBG60954.1 - 4.1e-112 372.8 0.0 7.7e-72 241.2 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 GBG60954.1 - 6.7e-39 133.0 0.0 1.3e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 GBG60954.1 - 1.3e-18 66.9 0.0 3.8e-18 65.4 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 GBG60954.1 - 3.1e-11 43.1 0.0 2.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GBG60954.1 - 2.5e-10 40.2 0.0 0.00036 20.1 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 GBG60954.1 - 5.3e-08 32.6 0.0 0.0024 17.5 0.0 3.3 4 1 0 4 4 4 2 ATP-grasp domain ATP-grasp_3 PF02655.14 GBG60954.1 - 0.00021 21.4 0.0 0.47 10.5 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 GBG60954.1 - 0.00022 20.8 0.0 0.0049 16.3 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 GBG60954.1 - 0.0035 17.0 0.0 0.5 9.9 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 GBG60954.1 - 0.0041 16.7 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain DUF4176 PF13780.6 GBG60954.1 - 0.1 12.6 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) DUF4360 PF14273.6 GBG60956.1 - 3.7e-39 134.4 1.0 4.3e-39 134.2 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF659 PF04937.15 GBG60957.1 - 5.1e-31 107.6 0.0 8.7e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60957.1 - 8.9e-09 35.0 0.3 1.4e-07 31.2 0.1 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Zn-ribbon_8 PF09723.10 GBG60957.1 - 0.038 14.1 2.2 9.1 6.5 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.21 GBG60957.1 - 0.062 13.4 0.3 19 5.5 0.0 2.6 2 0 0 2 2 2 0 FYVE zinc finger zinc_ribbon_4 PF13717.6 GBG60957.1 - 0.12 12.3 0.0 19 5.3 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 GBG60957.1 - 0.19 12.6 0.8 52 5.1 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 GBG60957.1 - 0.45 11.1 1.9 38 4.9 0.1 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain RNA_polI_A34 PF08208.11 GBG60957.1 - 0.61 10.1 6.2 1.4 8.9 6.2 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 MSC PF09402.10 GBG60958.1 - 3.7e-09 36.5 4.4 2.9e-08 33.6 4.4 2.3 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain Thymopoietin PF08198.11 GBG60958.1 - 0.0019 17.7 0.2 0.0039 16.7 0.2 1.5 1 0 0 1 1 1 1 Thymopoietin protein Pkinase PF00069.25 GBG60961.1 - 1.8e-70 237.3 0.0 2e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG60961.1 - 1.2e-27 96.9 0.0 1.5e-27 96.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG60961.1 - 3.8e-06 27.0 0.1 0.037 13.9 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG60961.1 - 7.9e-05 21.8 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GBG60961.1 - 0.0001 21.8 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GBG60961.1 - 0.0085 15.4 0.8 0.12 11.7 0.2 2.7 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 GBG60961.1 - 0.17 10.9 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RCC1 PF00415.18 GBG60962.1 - 7.5e-46 154.5 22.0 5.7e-13 49.3 0.5 7.3 6 1 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG60962.1 - 1.2e-11 44.1 35.4 0.00017 21.3 0.2 6.9 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat ANAPC4_WD40 PF12894.7 GBG60962.1 - 1.9e-06 28.1 0.1 0.038 14.3 0.0 3.3 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GBG60962.1 - 2.9e-06 27.9 1.0 1.5 9.8 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat RT_RNaseH_2 PF17919.1 GBG60963.1 - 7.1e-32 109.4 0.0 1.8e-15 56.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60963.1 - 2.5e-30 104.8 0.0 5.4e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60963.1 - 4.3e-28 98.4 0.0 7.1e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG60963.1 - 3.7e-09 36.6 0.1 8e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Integrase_H2C2 PF17921.1 GBG60964.1 - 8.3e-14 51.4 0.3 1.7e-13 50.5 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60964.1 - 4.1e-13 49.5 0.0 1.2e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG60964.1 - 0.016 15.4 0.6 0.036 14.3 0.6 1.7 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG60965.1 - 2.8e-09 37.4 0.1 3.6e-08 33.8 0.0 2.6 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60965.1 - 9.4e-08 32.6 0.0 4.1e-06 27.3 0.0 3.0 3 1 1 4 4 4 1 Aspartyl protease Asp_protease PF09668.10 GBG60965.1 - 0.0037 17.0 0.2 0.0075 16.1 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG60965.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 GBG60966.1 - 5.7e-12 45.9 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG60966.1 - 1.3e-06 28.9 0.1 3.7e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60966.1 - 4.6e-06 27.1 0.1 1.1e-05 25.9 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG60966.1 - 0.16 11.8 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease RRM_1 PF00076.22 GBG60967.1 - 3.8e-23 81.1 0.2 3.3e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GBG60967.1 - 7.1e-09 35.3 0.0 0.00038 20.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 GBG60967.1 - 0.011 14.0 63.0 0.11 10.7 41.1 2.1 2 0 0 2 2 2 0 Nop14-like family DDHD PF02862.17 GBG60967.1 - 0.061 13.5 3.8 0.59 10.2 0.4 2.4 2 0 0 2 2 2 0 DDHD domain BUD22 PF09073.10 GBG60967.1 - 0.58 9.4 61.2 0.81 9.0 38.6 2.1 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 GBG60967.1 - 1.4 8.3 73.4 1 8.7 46.4 2.1 2 0 0 2 2 2 0 SDA1 DA1-like PF12315.8 GBG60971.1 - 1.5e-31 109.4 0.1 1.9e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 Protein DA1 rve PF00665.26 GBG60972.1 - 1.8e-05 24.9 0.0 3.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG60973.1 - 3.2e-30 105.3 0.1 6.5e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60973.1 - 4.7e-08 33.0 0.0 1.3e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LIM PF00412.22 GBG60973.1 - 3.9e-07 30.2 2.3 8.4e-07 29.1 2.3 1.5 1 0 0 1 1 1 1 LIM domain RVP_2 PF08284.11 GBG60973.1 - 1e-06 28.5 0.0 3.5e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60973.1 - 0.00011 22.8 0.0 0.00032 21.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60973.1 - 0.00011 22.6 0.0 0.00032 21.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG60973.1 - 0.0078 16.5 0.0 0.035 14.4 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG60973.1 - 0.033 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF1664 PF07889.12 GBG60973.1 - 0.13 12.3 1.0 0.27 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RVT_1 PF00078.27 GBG60974.1 - 3e-30 105.4 0.1 6.2e-30 104.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG60974.1 - 4.5e-08 33.0 0.0 1.3e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LIM PF00412.22 GBG60974.1 - 3.7e-07 30.3 2.3 8.2e-07 29.2 2.3 1.5 1 0 0 1 1 1 1 LIM domain RVP_2 PF08284.11 GBG60974.1 - 9.8e-07 28.6 0.0 3.4e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG60974.1 - 0.00011 22.8 0.0 0.00031 21.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG60974.1 - 0.00011 22.7 0.0 0.00031 21.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG60974.1 - 0.0073 16.6 0.0 0.034 14.4 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG60974.1 - 0.031 14.1 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF1664 PF07889.12 GBG60974.1 - 0.12 12.4 1.0 0.27 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Copper-bind PF00127.20 GBG60975.1 - 4.5e-24 84.8 0.0 8.2e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 GBG60975.1 - 3.5e-08 33.5 0.0 8.1e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Cupredoxin-like domain Myb_DNA-binding PF00249.31 GBG60976.1 - 0.06 13.6 1.4 0.15 12.3 0.6 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pkinase_Tyr PF07714.17 GBG60977.1 - 1.9e-41 142.1 0.0 6.6e-41 140.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG60977.1 - 3.2e-40 138.2 0.0 4.4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG60977.1 - 0.00076 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG60977.1 - 0.0013 18.7 0.6 0.041 13.8 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family PIP49_C PF12260.8 GBG60977.1 - 0.065 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF659 PF04937.15 GBG60979.1 - 3.9e-30 104.7 0.0 6.5e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG60979.1 - 0.00042 20.0 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LysM PF01476.20 GBG60980.1 - 1.8e-08 34.3 0.1 7.6e-06 25.9 0.1 2.8 3 0 0 3 3 3 2 LysM domain LysM PF01476.20 GBG60981.1 - 1.7e-08 34.4 0.1 7.4e-06 25.9 0.1 2.8 3 0 0 3 3 3 2 LysM domain TEBP_beta PF07404.11 GBG60982.1 - 0.027 13.8 0.3 0.28 10.5 0.1 2.0 1 1 1 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) Cyclase_polyket PF04673.12 GBG60982.1 - 0.05 13.9 0.6 0.39 11.0 0.0 2.6 3 0 0 3 3 3 0 Polyketide synthesis cyclase RVP PF00077.20 GBG60984.1 - 0.029 14.7 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG60984.1 - 0.063 13.9 0.1 0.18 12.4 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG60984.1 - 0.15 12.7 0.1 0.35 11.5 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease Ebp2 PF05890.12 GBG60985.1 - 1.3e-68 231.5 11.6 1.3e-68 231.5 11.6 4.0 4 0 0 4 4 4 1 Eukaryotic rRNA processing protein EBP2 E1_UFD PF09358.10 GBG60985.1 - 4.5 8.0 5.1 9.1 7.1 1.6 2.6 2 0 0 2 2 2 0 Ubiquitin fold domain RT_RNaseH PF17917.1 GBG60986.1 - 6.8e-22 77.8 0.0 1.7e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60986.1 - 2.7e-20 72.3 0.0 5e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG60986.1 - 1.3e-17 63.6 0.4 2.5e-17 62.7 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG60986.1 - 3.6e-10 40.1 0.1 1.6e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Abhydrolase_1 PF00561.20 GBG60987.1 - 9.7e-22 77.8 0.0 3.5e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG60987.1 - 1.3e-17 65.2 0.1 2.2e-17 64.4 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG60987.1 - 0.00015 21.1 0.0 0.0018 17.6 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GBG60987.1 - 0.0031 17.7 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 GBG60987.1 - 0.0032 17.0 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 GBG60987.1 - 0.0051 16.8 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 GBG60987.1 - 0.026 14.6 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.14 GBG60987.1 - 0.035 12.8 0.0 1.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Ndr family DUF1100 PF06500.11 GBG60987.1 - 0.2 10.4 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) RT_RNaseH_2 PF17919.1 GBG60988.1 - 2.1e-30 104.7 0.0 5.9e-30 103.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60988.1 - 4.8e-29 100.7 0.0 1e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60988.1 - 2.1e-12 47.1 0.0 3.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PCMT PF01135.19 GBG60989.1 - 5.7e-79 264.7 0.0 7.8e-79 264.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GBG60989.1 - 2.5e-07 30.6 0.0 9.5e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GBG60989.1 - 5.2e-05 22.8 0.0 7.9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GBG60989.1 - 0.00054 20.6 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG60989.1 - 0.00084 19.2 0.0 0.0019 18.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG60989.1 - 0.0042 17.7 0.0 0.021 15.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GBG60989.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 GBG60989.1 - 0.04 13.6 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Fibrillarin PF01269.17 GBG60989.1 - 0.058 12.5 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin CMAS PF02353.20 GBG60989.1 - 0.23 10.7 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CDC45 PF02724.14 GBG60991.1 - 4.1 5.6 9.5 5.7 5.1 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG60991.1 - 10 4.2 9.0 13 3.8 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG60992.1 - 2.1e-26 91.9 0.0 3.5e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG60992.1 - 2.1e-23 82.6 0.0 3.8e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60992.1 - 2.8e-11 43.4 0.1 4.1e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG60992.1 - 0.73 8.0 6.6 0.91 7.7 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG60992.1 - 1.9 7.9 9.4 2.6 7.4 9.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG60992.1 - 6.5 4.9 7.8 8.3 4.6 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG60994.1 - 3.7e-22 78.8 0.1 1.1e-20 74.1 0.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3537 PF12056.8 GBG60994.1 - 0.22 10.3 0.0 0.22 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) zf-BED PF02892.15 GBG60994.1 - 0.31 11.1 2.0 0.85 9.7 2.0 1.7 1 0 0 1 1 1 0 BED zinc finger SDA1 PF05285.12 GBG60994.1 - 4.2 6.7 35.4 6.8 6.0 35.4 1.3 1 0 0 1 1 1 0 SDA1 RT_RNaseH PF17917.1 GBG60995.1 - 3.7e-18 65.8 0.1 9.3e-18 64.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG60995.1 - 5.3e-11 42.4 0.0 9.9e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG60995.1 - 6.3e-05 22.6 0.1 0.00013 21.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fzo_mitofusin PF04799.13 GBG60996.1 - 0.0025 17.4 1.0 0.0033 17.0 0.2 1.6 1 1 1 2 2 2 1 fzo-like conserved region DUF3450 PF11932.8 GBG60996.1 - 5.6 6.2 14.2 0.59 9.4 6.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MAP7 PF05672.11 GBG60996.1 - 6.7 6.4 35.3 1.3 8.7 7.8 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family CG-1 PF03859.16 GBG60997.1 - 2.2e-43 146.8 2.0 3.5e-43 146.1 2.0 1.3 1 0 0 1 1 1 1 CG-1 domain RNA_pol_3_Rpc31 PF11705.8 GBG60997.1 - 0.0033 17.7 8.7 0.0033 17.7 8.7 3.0 3 0 0 3 3 2 1 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 GBG60997.1 - 0.0036 16.8 6.3 0.0036 16.8 6.3 2.1 2 1 0 2 2 2 1 SDA1 Radial_spoke PF04712.12 GBG60997.1 - 0.014 14.3 7.7 0.024 13.6 7.7 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein Ribosomal_60s PF00428.19 GBG60997.1 - 0.041 14.5 18.7 0.13 12.9 18.7 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Acyl-ACP_TE PF01643.17 GBG60997.1 - 0.054 12.8 0.5 0.085 12.1 0.5 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase DUF4746 PF15928.5 GBG60997.1 - 0.11 11.9 9.3 0.2 11.1 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MMM1 PF10296.9 GBG60997.1 - 0.24 10.4 2.9 2.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Pox_Ag35 PF03286.14 GBG60997.1 - 0.31 10.8 10.6 0.98 9.2 10.6 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4820 PF16091.5 GBG60997.1 - 0.82 9.0 5.0 2 7.7 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FYDLN_acid PF09538.10 GBG60997.1 - 0.86 10.3 16.0 0.055 14.2 5.7 3.1 4 0 0 4 4 3 0 Protein of unknown function (FYDLN_acid) TLP-20 PF06088.11 GBG60997.1 - 1.5 8.7 4.5 4.6 7.1 4.5 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CPSF100_C PF13299.6 GBG60997.1 - 2.2 8.5 6.3 0.25 11.5 1.4 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 GBG60997.1 - 2.3 7.4 7.7 4.1 6.5 7.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2052 PF09747.9 GBG60997.1 - 2.3 8.3 19.7 5.3 7.1 19.2 1.9 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NOA36 PF06524.12 GBG60997.1 - 3.2 7.0 26.7 0.82 8.9 13.6 3.0 3 0 0 3 3 3 0 NOA36 protein RPN2_C PF18004.1 GBG60997.1 - 3.3 7.6 9.6 9.3 6.1 9.6 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Myc_N PF01056.18 GBG60997.1 - 5.1 6.9 20.0 0.056 13.3 7.8 2.7 2 1 0 2 2 2 0 Myc amino-terminal region Nop14 PF04147.12 GBG60997.1 - 5.3 5.1 18.7 0.0069 14.7 7.8 1.6 2 0 0 2 2 2 0 Nop14-like family SpoIIIAH PF12685.7 GBG60997.1 - 7.3 6.4 10.5 13 5.5 10.5 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein PPP4R2 PF09184.11 GBG60997.1 - 9.8 5.7 20.3 0.93 9.0 10.5 2.2 2 0 0 2 2 2 0 PPP4R2 CDC45 PF02724.14 GBG60998.1 - 0.25 9.6 1.0 0.24 9.7 1.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 GBG60998.1 - 1.1 9.2 5.4 1.4 8.7 5.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CG-1 PF03859.16 GBG60999.1 - 7.4e-43 145.0 2.4 1.5e-42 144.0 2.4 1.6 1 0 0 1 1 1 1 CG-1 domain SAPS PF04499.15 GBG60999.1 - 0.0036 16.2 8.8 0.0051 15.7 8.8 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SpoIIP PF07454.11 GBG60999.1 - 0.071 12.6 5.3 0.63 9.5 4.9 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Na_trans_assoc PF06512.13 GBG60999.1 - 0.089 13.1 14.3 0.18 12.1 14.3 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated PPP4R2 PF09184.11 GBG60999.1 - 0.13 11.8 17.8 0.25 10.9 17.8 1.4 1 0 0 1 1 1 0 PPP4R2 Cellulose_synt PF03552.14 GBG60999.1 - 0.21 10.1 0.9 0.33 9.4 0.9 1.2 1 0 0 1 1 1 0 Cellulose synthase TRAP_alpha PF03896.16 GBG60999.1 - 0.82 8.8 5.5 1.9 7.6 5.5 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Hid1 PF12722.7 GBG60999.1 - 2.2 6.3 4.3 2.9 5.9 4.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CRA PF06589.11 GBG60999.1 - 4.4 7.4 5.0 2.5e+02 1.7 7.0 2.4 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) V_ATPase_I PF01496.19 GBG60999.1 - 9.9 3.9 8.6 15 3.4 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4148 PF13663.6 GBG61000.1 - 0.36 11.1 2.1 0.65 10.2 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) RT_RNaseH_2 PF17919.1 GBG61001.1 - 3e-31 107.4 0.1 5.6e-31 106.5 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61001.1 - 2.6e-29 101.6 0.3 5.1e-29 100.6 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61001.1 - 1.3e-19 70.1 0.1 3.1e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61001.1 - 1.3e-11 44.7 0.0 3.7e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG61002.1 - 6e-28 97.9 0.1 3.9e-27 95.2 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG61002.1 - 0.063 13.5 11.3 0.38 11.1 0.0 4.7 6 0 0 6 6 6 0 Retrotransposon gag protein AIP3 PF03915.13 GBG61002.1 - 0.26 10.4 9.1 0.31 10.1 7.4 2.1 1 1 0 1 1 1 0 Actin interacting protein 3 ERM PF00769.19 GBG61002.1 - 0.35 10.6 24.3 0.13 12.1 20.9 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 GBG61002.1 - 0.35 10.9 3.5 8 6.5 0.3 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Sulfatase_C PF14707.6 GBG61002.1 - 6.7 7.5 6.8 1 10.1 0.9 2.7 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase Integrase_H2C2 PF17921.1 GBG61003.1 - 8.1e-16 57.9 0.5 1.6e-15 56.9 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61003.1 - 6.1e-15 55.5 0.0 4.6e-14 52.6 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG61003.1 - 0.0046 17.2 0.1 0.015 15.5 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Transposase_31 PF04754.12 GBG61003.1 - 0.053 13.1 0.2 0.098 12.2 0.2 1.4 1 0 0 1 1 1 0 Putative transposase, YhgA-like RT_RNaseH_2 PF17919.1 GBG61004.1 - 1.1e-32 112.1 0.0 1.8e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61004.1 - 2.5e-30 105.6 0.1 3.5e-30 105.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61004.1 - 1.2e-29 102.7 0.1 2.1e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5095 PF17016.5 GBG61004.1 - 0.067 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Beta_helix PF13229.6 GBG61005.1 - 5.7e-07 29.5 1.2 7.1e-06 25.9 2.6 1.9 1 1 1 2 2 2 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG61005.1 - 3.8e-05 23.9 14.8 0.094 13.2 0.1 5.5 5 0 0 5 5 5 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NosD PF05048.13 GBG61005.1 - 0.049 12.9 0.1 0.065 12.5 0.1 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) zf-C2H2_jaz PF12171.8 GBG61006.1 - 0.12 12.7 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Med2 PF11214.8 GBG61007.1 - 0.067 13.4 0.7 0.067 13.4 0.7 2.4 2 1 1 3 3 3 0 Mediator complex subunit 2 Integrase_H2C2 PF17921.1 GBG61008.1 - 9.2e-20 70.5 0.2 3.9e-19 68.5 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG61008.1 - 2.8e-17 62.9 0.1 7.3e-17 61.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61008.1 - 1.1e-10 41.4 0.0 2.8e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG61008.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG61008.1 - 0.075 13.3 0.7 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger YjbH PF06082.11 GBG61008.1 - 0.31 9.8 6.1 0.46 9.2 6.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH CLZ PF16526.5 GBG61008.1 - 3.8 7.9 5.3 3.1 8.2 2.8 2.2 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 GBG61010.1 - 0.37 10.1 7.1 0.67 9.3 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 GBG61010.1 - 7.4 5.1 5.7 11 4.5 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) VPS13 PF16908.5 GBG61011.1 - 6.1e-06 26.2 0.0 7.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal rve PF00665.26 GBG61012.1 - 3.8e-15 56.1 0.0 6.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG61012.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DUF3169 PF11368.8 GBG61018.1 - 0.15 11.5 0.1 0.15 11.5 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3169) SHR-BD PF06650.12 GBG61019.1 - 7.8e-46 156.6 0.0 2.4e-44 151.8 0.0 3.0 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 C2 PF00168.30 GBG61019.1 - 2.8e-38 130.3 0.4 8.1e-19 67.8 0.1 2.6 2 0 0 2 2 2 2 C2 domain Apt1 PF10351.9 GBG61019.1 - 4.5e-06 25.8 0.0 4.5e-06 25.8 0.0 3.4 4 0 0 4 4 4 1 Golgi-body localisation protein domain RT_RNaseH_2 PF17919.1 GBG61020.1 - 4.1e-30 103.8 0.0 7.7e-30 102.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61020.1 - 5.1e-28 97.4 0.0 1e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG61020.1 - 0.02 15.2 0.0 0.051 13.9 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein VPS13_C PF16909.5 GBG61021.1 - 1.4e-10 41.2 0.2 7.7e-07 29.0 0.0 2.9 2 1 1 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal GCIP PF13324.6 GBG61021.1 - 0.44 10.1 4.4 1.1 8.8 4.4 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RNA_pol_Rpc4 PF05132.14 GBG61023.1 - 0.014 15.8 4.3 0.026 15.0 4.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2828 PF11443.8 GBG61023.1 - 0.063 11.4 1.7 0.087 10.9 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4746 PF15928.5 GBG61023.1 - 0.1 12.0 17.6 0.17 11.3 17.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Na_trans_assoc PF06512.13 GBG61023.1 - 0.14 12.4 15.4 0.2 11.9 15.4 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated PPP4R2 PF09184.11 GBG61023.1 - 0.15 11.6 18.1 0.2 11.2 18.1 1.1 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 GBG61023.1 - 2.1 7.1 8.4 2.8 6.6 8.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ABC2_membrane PF01061.24 GBG61024.1 - 1.3e-28 99.9 23.9 1.3e-28 99.9 23.9 2.3 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 GBG61024.1 - 7.9e-25 88.0 0.0 1.3e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG61024.1 - 0.00033 19.9 21.8 0.00066 18.9 21.8 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG61024.1 - 0.0014 18.5 0.7 1.3 8.8 0.4 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GBG61024.1 - 0.0016 19.0 0.1 0.0028 18.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GBG61024.1 - 0.0042 16.2 0.3 0.0082 15.2 0.3 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 GBG61024.1 - 0.011 15.6 0.2 0.022 14.7 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 GBG61024.1 - 0.012 15.3 0.2 0.038 13.7 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG61024.1 - 0.076 13.3 0.2 0.24 11.7 0.2 1.8 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 GBG61024.1 - 0.22 10.7 23.3 0.028 13.7 13.7 3.0 3 0 0 3 3 3 0 ABC-2 family transporter protein COPIIcoated_ERV PF07970.12 GBG61025.1 - 3.9e-91 304.8 0.4 5.5e-91 304.3 0.4 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GBG61025.1 - 5.8e-31 106.7 1.3 7.8e-31 106.3 0.1 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RVT_1 PF00078.27 GBG61026.1 - 1.1e-26 93.7 0.1 1.7e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG61027.1 - 8.5e-28 97.4 0.1 1.9e-27 96.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG61027.1 - 0.0043 17.3 6.8 0.0078 16.5 2.3 3.5 2 1 1 3 3 3 1 Retrotransposon gag protein ZapB PF06005.12 GBG61027.1 - 0.011 16.2 0.4 0.011 16.2 0.4 3.6 5 0 0 5 5 5 0 Cell division protein ZapB DUF2884 PF11101.8 GBG61027.1 - 0.03 13.8 1.0 0.075 12.5 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) TSC22 PF01166.18 GBG61027.1 - 2.1 8.7 5.6 1.5 9.2 0.9 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family Glyco_tranf_2_2 PF10111.9 GBG61028.1 - 0.00048 19.7 0.0 0.0007 19.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 GBG61028.1 - 0.00069 19.2 0.0 0.0022 17.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 GBG61028.1 - 0.045 13.6 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG61028.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Myb_DNA-bind_4 PF13837.6 GBG61031.1 - 2.8e-12 46.9 0.6 2.8e-12 46.9 0.6 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG61031.1 - 0.028 14.6 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG61031.1 - 1.5 9.2 5.9 0.26 11.6 0.3 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Astro_capsid_p PF12226.8 GBG61032.1 - 0.34 10.0 4.1 0.44 9.6 4.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 GBG61032.1 - 3.1 7.0 5.3 3.8 6.7 5.3 1.1 1 0 0 1 1 1 0 NOA36 protein AlaDh_PNT_C PF01262.21 GBG61032.1 - 3.3 6.9 7.5 0.89 8.8 2.7 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CENP-B_dimeris PF09026.10 GBG61032.1 - 5.1 7.5 10.9 9.4 6.7 10.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PT-VENN PF04829.13 GBG61032.1 - 5.9 7.1 6.1 12 6.1 0.8 2.8 1 1 1 2 2 2 0 Pre-toxin domain with VENN motif DDE_Tnp_4 PF13359.6 GBG61033.1 - 2.7e-22 79.1 0.0 3.6e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61033.1 - 4.6e-14 52.5 0.0 1.1e-13 51.3 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein Rhomboid PF01694.22 GBG61034.1 - 1.7e-27 96.3 12.3 3.3e-27 95.3 12.3 1.5 1 0 0 1 1 1 1 Rhomboid family DUF588 PF04535.12 GBG61034.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF588) CopD PF05425.13 GBG61034.1 - 1.7 9.1 0.0 1.7 9.1 0.0 3.3 3 1 1 4 4 4 0 Copper resistance protein D DUF4884 PF16225.5 GBG61036.1 - 0.54 10.4 3.0 18 5.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4884) RT_RNaseH_2 PF17919.1 GBG61037.1 - 1e-32 112.1 0.1 3.4e-15 55.9 0.0 3.5 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61037.1 - 2.6e-30 105.6 0.0 6.6e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61037.1 - 2.8e-30 104.7 0.2 2.5e-18 66.3 0.9 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61037.1 - 4.9e-17 61.8 0.3 1.3e-16 60.4 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG61037.1 - 9.6e-05 22.5 0.0 0.00024 21.2 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG61037.1 - 0.00049 20.0 1.0 0.0012 18.8 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle rve PF00665.26 GBG61037.1 - 0.029 14.5 0.0 0.094 12.9 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain HTH_20 PF12840.7 GBG61037.1 - 0.14 12.3 3.1 12 6.0 0.0 4.2 4 0 0 4 4 4 0 Helix-turn-helix domain zf-CCHC PF00098.23 GBG61037.1 - 0.15 12.2 4.7 0.38 10.9 4.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Peptidase_S64 PF08192.11 GBG61037.1 - 0.2 10.1 2.1 0.39 9.1 2.1 1.4 1 0 0 1 1 1 0 Peptidase family S64 FAM199X PF15814.5 GBG61037.1 - 7.9 5.4 10.3 14 4.6 10.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X zf-CCHC PF00098.23 GBG61038.1 - 4.9e-05 23.2 3.3 4.9e-05 23.2 3.3 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG61038.1 - 0.09 12.5 1.1 0.17 11.6 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Vta1 PF04652.16 GBG61038.1 - 0.13 12.3 3.6 0.21 11.6 3.5 1.5 1 1 0 1 1 1 0 Vta1 like zf-CCHC_2 PF13696.6 GBG61038.1 - 0.23 11.3 3.7 0.59 10.0 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Cwf_Cwc_15 PF04889.12 GBG61038.1 - 0.68 9.6 10.4 1.4 8.6 10.4 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RVT_1 PF00078.27 GBG61039.1 - 1.3e-26 93.5 0.1 5.2e-25 88.3 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4187 PF13821.6 GBG61039.1 - 0.016 15.0 1.1 0.048 13.4 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG61039.1 - 0.021 15.1 0.2 0.021 15.1 0.2 3.6 4 0 0 4 4 4 0 Retrotransposon gag protein AC_N PF16214.5 GBG61039.1 - 0.094 11.8 1.7 0.21 10.7 1.7 1.5 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region CENP-K PF11802.8 GBG61039.1 - 0.12 11.9 1.7 0.29 10.7 1.7 1.6 1 0 0 1 1 1 0 Centromere-associated protein K Lipin_mid PF16876.5 GBG61039.1 - 0.14 12.4 0.6 0.5 10.6 0.0 2.2 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF659 PF04937.15 GBG61040.1 - 1.5e-30 106.1 0.0 2.5e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF678 PF05077.12 GBG61040.1 - 0.059 13.5 2.6 0.16 12.1 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF678) RVT_1 PF00078.27 GBG61042.1 - 1.4e-22 80.3 0.1 2.3e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG61042.1 - 7.8e-12 45.1 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.14 GBG61042.1 - 5.9e-08 32.4 0.2 1.5e-07 31.1 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Plant_tran PF04827.14 GBG61042.1 - 7.4e-06 25.7 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61042.1 - 0.045 13.4 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Transposase DDE domain LAP1C PF05609.12 GBG61042.1 - 3.2 6.8 18.5 5.5 6.0 18.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_C50 PF03568.17 GBG61043.1 - 4.9e-91 305.8 0.0 1.5e-71 241.6 0.0 2.9 2 0 0 2 2 2 2 Peptidase family C50 CHAT PF12770.7 GBG61043.1 - 1.9e-05 24.2 0.1 9.3e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 CHAT domain TPR_1 PF00515.28 GBG61043.1 - 0.58 10.1 3.2 2.5 8.1 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG61043.1 - 1 9.7 4.1 7.1 7.0 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG61044.1 - 0.19 11.6 3.1 1.7 8.6 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C50 PF03568.17 GBG61045.1 - 1.8e-92 310.5 0.0 2.8e-72 244.0 0.0 2.8 2 2 0 2 2 2 2 Peptidase family C50 CHAT PF12770.7 GBG61045.1 - 2e-06 27.5 0.1 2.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 CHAT domain DUF778 PF05608.12 GBG61046.1 - 1.4e-39 136.4 1.9 1.6e-20 74.3 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF3446 PF11928.8 GBG61046.1 - 0.2 12.0 4.8 0.32 11.3 4.8 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain WD40 PF00400.32 GBG61049.1 - 3.3e-28 97.4 19.1 7.3e-06 26.6 0.2 6.6 5 1 1 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 GBG61049.1 - 3.3e-21 75.6 0.1 5.1e-21 75.0 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 GBG61049.1 - 0.0047 17.2 2.9 0.056 13.7 0.3 3.2 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_8 PF06259.12 GBG61049.1 - 0.0082 15.8 0.5 0.015 15.0 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Nup160 PF11715.8 GBG61049.1 - 0.41 9.2 11.0 0.67 8.5 0.5 3.8 1 1 3 4 4 4 0 Nucleoporin Nup120/160 zf-RING_2 PF13639.6 GBG61050.1 - 2e-08 34.4 1.3 3.5e-08 33.6 1.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GBG61050.1 - 8.7e-08 31.8 2.1 1.8e-07 30.8 2.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GBG61050.1 - 8e-06 26.0 1.4 1.7e-05 25.0 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GBG61050.1 - 1.7e-05 24.5 0.6 3.2e-05 23.7 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GBG61050.1 - 0.00019 21.0 2.3 0.00039 20.0 2.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 GBG61050.1 - 0.00029 20.8 0.4 0.00055 19.9 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG61050.1 - 0.0011 18.9 0.8 0.0021 18.0 0.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG61050.1 - 0.0013 18.5 0.5 0.0025 17.6 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GBG61050.1 - 0.0042 17.1 2.1 0.023 14.7 2.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 GBG61050.1 - 0.012 15.5 1.2 0.025 14.5 1.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 GBG61050.1 - 0.038 14.1 1.2 0.075 13.2 1.2 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger Vps39_2 PF10367.9 GBG61050.1 - 0.1 13.1 0.1 0.17 12.4 0.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 PHD PF00628.29 GBG61050.1 - 0.16 11.9 1.0 0.35 10.8 1.0 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 GBG61050.1 - 0.21 11.8 1.7 0.39 10.9 1.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 GBG61050.1 - 2.1 8.4 4.1 0.56 10.3 0.3 1.9 2 0 0 2 2 2 0 Zinc-finger DUF659 PF04937.15 GBG61051.1 - 1.6e-13 50.8 0.0 2.4e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DDE_Tnp_4 PF13359.6 GBG61051.1 - 1.5e-08 34.5 0.0 4.1e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol3_beta_3 PF02768.15 GBG61051.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain Plant_tran PF04827.14 GBG61051.1 - 0.22 11.1 0.0 0.4 10.3 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG61053.1 - 7.2e-05 23.1 0.8 0.00014 22.1 0.8 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG61053.1 - 0.0063 16.6 0.5 0.0063 16.6 0.5 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain CHD5 PF04420.14 GBG61054.1 - 5.9e-05 23.0 0.1 7.8e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 CHD5-like protein CHD5 PF04420.14 GBG61055.1 - 1.1e-05 25.4 0.2 1.4e-05 25.0 0.2 1.1 1 0 0 1 1 1 1 CHD5-like protein EMC3_TMCO1 PF01956.16 GBG61055.1 - 0.026 14.3 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RPAP3_C PF13877.6 GBG61056.1 - 2e-23 82.7 0.0 4.3e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 GBG61056.1 - 1.3e-21 75.4 7.3 1.7e-07 30.8 0.9 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG61056.1 - 1.3e-17 62.4 7.8 3.2e-05 23.7 1.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG61056.1 - 2e-10 40.0 3.9 0.00095 19.2 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG61056.1 - 7.5e-07 29.3 0.6 4.5e-05 23.7 0.4 4.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GBG61056.1 - 3e-06 27.8 0.0 3e-06 27.8 0.0 4.6 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG61056.1 - 6.9e-06 25.6 9.9 0.0023 17.6 0.0 3.6 2 1 2 4 4 3 3 TPR repeat TPR_7 PF13176.6 GBG61056.1 - 0.0032 17.4 4.1 3.5 7.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG61056.1 - 0.0045 17.7 14.2 0.091 13.6 0.0 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 GBG61056.1 - 0.0098 15.3 0.7 5.9 6.4 0.2 3.3 3 0 0 3 3 3 1 SHNi-TPR TPR_9 PF13371.6 GBG61056.1 - 0.022 14.9 0.4 0.022 14.9 0.4 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG61056.1 - 0.056 13.3 0.2 0.056 13.3 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG61056.1 - 0.066 13.4 1.1 2.8 8.2 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 GBG61056.1 - 0.18 11.9 2.9 2.7 8.1 0.5 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 GBG61056.1 - 0.2 12.1 1.1 11 6.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG61056.1 - 0.94 10.0 17.9 0.35 11.4 0.2 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat Cornichon PF03311.14 GBG61058.1 - 3.9e-40 137.0 8.0 4.8e-40 136.7 8.0 1.0 1 0 0 1 1 1 1 Cornichon protein ECF_trnsprt PF12822.7 GBG61058.1 - 0.022 14.8 0.3 0.041 14.0 0.3 1.4 1 1 0 1 1 1 0 ECF transporter, substrate-specific component BatA PF07584.11 GBG61058.1 - 5.1 7.5 11.6 0.12 12.7 0.8 2.2 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal SNARE PF05739.19 GBG61058.1 - 8.3 6.5 6.7 12 6.0 0.3 2.7 2 0 0 2 2 2 0 SNARE domain SYF2 PF08231.12 GBG61059.1 - 4e-34 118.3 0.7 7.3e-34 117.5 0.7 1.5 1 0 0 1 1 1 1 SYF2 splicing factor SRP9-21 PF05486.12 GBG61060.1 - 2.2e-10 40.8 0.5 7.4e-09 35.9 0.5 2.3 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) MRNIP PF15749.5 GBG61061.1 - 2.2 9.0 11.0 6.7 7.5 11.0 2.0 1 1 0 1 1 1 0 MRN-interacting protein NARP1 PF12569.8 GBG61061.1 - 3.2 6.6 15.3 5.7 5.7 15.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNB PF00773.19 GBG61062.1 - 7.2e-20 71.6 0.0 1.9e-19 70.2 0.0 1.6 2 0 0 2 2 2 1 RNB domain Rrp44_S1 PF17215.3 GBG61062.1 - 0.0067 16.4 0.0 0.021 14.8 0.0 1.9 1 1 0 1 1 1 1 S1 domain PRR18 PF15671.5 GBG61062.1 - 0.02 14.8 0.6 0.066 13.1 0.6 1.8 1 0 0 1 1 1 0 Proline-rich protein family 18 Anophelin PF10731.9 GBG61064.1 - 6 6.8 9.2 24 4.9 9.2 2.1 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito RNB PF00773.19 GBG61065.1 - 2.1e-22 79.9 0.0 3e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 RNB domain RVT_1 PF00078.27 GBG61066.1 - 1.4e-13 50.9 0.1 2.5e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61066.1 - 1.2e-05 25.0 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG61066.1 - 0.00047 20.0 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61066.1 - 0.00054 20.5 0.0 0.0026 18.3 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61066.1 - 0.00061 20.4 0.0 0.0019 18.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease AT_hook PF02178.19 GBG61066.1 - 0.11 12.4 5.8 0.38 10.8 5.8 2.0 1 0 0 1 1 1 0 AT hook motif DUF2730 PF10805.8 GBG61066.1 - 0.71 10.0 2.6 3.2 7.9 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) RNB PF00773.19 GBG61067.1 - 2.5e-25 89.5 0.0 5e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GBG61067.1 - 1.2e-21 76.5 0.0 4e-21 74.8 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 GBG61067.1 - 5.6e-06 26.4 0.1 9.1e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Cold shock domain WYL PF13280.6 GBG61067.1 - 0.021 14.9 1.6 0.086 12.9 1.2 2.3 1 1 0 1 1 1 0 WYL domain RT_RNaseH_2 PF17919.1 GBG61070.1 - 6e-47 157.8 0.2 4.4e-22 78.0 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61070.1 - 5.5e-40 135.9 0.0 2.3e-20 72.8 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61070.1 - 3.4e-38 131.4 0.7 1.7e-26 93.1 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61070.1 - 2.3e-07 30.6 0.0 5.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61070.1 - 2e-05 25.2 0.0 0.00015 22.4 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61070.1 - 2.5e-05 24.8 0.0 6.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG61070.1 - 0.065 13.5 0.1 0.065 13.5 0.1 3.2 4 0 0 4 4 4 0 Retrotransposon gag protein CDH1_2_SANT_HL1 PF18375.1 GBG61070.1 - 0.12 13.0 0.0 8.9 7.1 0.0 3.0 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Retrotrans_gag PF03732.17 GBG61071.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG61072.1 - 5.8e-32 109.7 0.0 1.2e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61072.1 - 1.2e-28 99.4 0.0 2.8e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61072.1 - 2.9e-19 68.9 0.1 6.2e-19 67.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG61072.1 - 4.3e-12 46.0 0.2 7.4e-12 45.2 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61072.1 - 1.4e-06 28.5 0.0 4.9e-05 23.5 0.0 2.9 2 1 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG61074.1 - 2e-23 82.3 0.0 5.3e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61074.1 - 1.4e-22 80.0 0.0 3.9e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61074.1 - 3e-21 76.0 0.0 5.6e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG61074.1 - 8.1e-12 45.1 0.6 8.1e-12 45.1 0.6 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG61074.1 - 3.5e-08 33.7 0.0 9.5e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain F-box-like PF12937.7 GBG61074.1 - 1.6e-06 27.9 0.2 6.7e-06 25.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GBG61074.1 - 0.00021 21.1 0.7 0.00021 21.1 0.7 2.3 2 0 0 2 2 2 1 F-box domain Retrotrans_gag PF03732.17 GBG61074.1 - 0.017 15.4 1.0 0.066 13.5 0.2 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein TFIIA PF03153.13 GBG61074.1 - 0.88 9.5 11.8 2 8.3 11.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mei5_like PF17021.5 GBG61075.1 - 0.23 11.5 6.9 0.73 9.9 1.6 2.2 2 0 0 2 2 2 0 Putative double-strand recombination repair-like DUF4139 PF13598.6 GBG61075.1 - 0.6 9.8 3.0 0.2 11.4 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4139) DUF4392 PF14336.6 GBG61075.1 - 7.9 5.8 6.7 0.34 10.3 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Rx_N PF18052.1 GBG61075.1 - 8 6.8 15.1 0.17 12.1 7.7 2.0 2 1 0 2 2 2 0 Rx N-terminal domain RVT_1 PF00078.27 GBG61076.1 - 2e-35 122.3 0.0 2.6e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Beta_helix PF13229.6 GBG61077.1 - 6e-07 29.4 5.8 0.014 15.2 4.1 2.4 1 1 1 2 2 2 2 Right handed beta helix region OPA3 PF07047.12 GBG61077.1 - 0.58 9.9 0.0 0.58 9.9 0.0 3.3 3 0 0 3 3 3 0 Optic atrophy 3 protein (OPA3) RVT_1 PF00078.27 GBG61078.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Acyltransferase PF01553.21 GBG61079.1 - 3.7e-08 33.1 0.0 5.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Intimin_C PF07979.11 GBG61079.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Intimin C-type lectin domain Lipocalin_2 PF08212.12 GBG61082.1 - 7.4e-06 26.0 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain Myb_DNA-bind_4 PF13837.6 GBG61087.1 - 5.9e-09 36.2 0.2 1e-07 32.3 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG61087.1 - 0.0044 17.1 0.4 0.012 15.6 0.4 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG61088.1 - 2.6e-30 105.2 0.0 4.8e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61088.1 - 1.5e-15 57.4 0.0 2.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61088.1 - 0.00077 19.2 1.2 0.63 9.6 0.0 2.8 3 0 0 3 3 3 2 Transposase DDE domain ALMT PF11744.8 GBG61089.1 - 0.082 11.7 7.2 0.043 12.7 4.2 1.8 2 0 0 2 2 2 0 Aluminium activated malate transporter DctA-YdbH PF11739.8 GBG61089.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Dicarboxylate transport VSG_B PF13206.6 GBG61089.1 - 0.17 11.1 15.6 0.23 10.7 15.4 1.5 1 1 0 1 1 1 0 Trypanosomal VSG domain LPP PF04728.13 GBG61089.1 - 0.25 11.7 2.7 0.73 10.3 2.7 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper TMPIT PF07851.13 GBG61089.1 - 0.51 9.5 7.5 0.92 8.7 7.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein Mitofilin PF09731.9 GBG61089.1 - 1.5 7.5 17.4 2.8 6.7 17.4 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tho2 PF11262.8 GBG61089.1 - 1.6 7.8 8.0 2.9 7.0 8.0 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 MDM10 PF12519.8 GBG61089.1 - 5.6 5.7 6.0 9.1 5.0 6.0 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RT_RNaseH PF17917.1 GBG61090.1 - 1.6e-19 70.1 0.0 4.6e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61090.1 - 4.4e-18 65.2 0.0 1.1e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61090.1 - 1e-06 28.5 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG61090.1 - 0.00023 21.7 0.0 0.00057 20.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG61090.1 - 0.0088 16.3 0.0 0.026 14.9 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61090.1 - 0.011 16.3 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG61090.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG61092.1 - 2.6e-22 79.3 0.0 4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG61095.1 - 2.4e-19 69.7 0.0 3.9e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pentapeptide_4 PF13599.6 GBG61095.1 - 0.005 17.0 0.2 1.2 9.3 0.2 3.1 2 1 1 3 3 3 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 GBG61095.1 - 0.064 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) MCR PF18509.1 GBG61095.1 - 0.33 10.6 2.4 2.6 7.7 0.4 2.4 2 0 0 2 2 2 0 Magnetochrome domain Vps53_N PF04100.12 GBG61096.1 - 0.36 9.8 11.0 0.35 9.8 8.0 1.9 1 1 1 2 2 2 0 Vps53-like, N-terminal 60KD_IMP PF02096.20 GBG61096.1 - 0.96 9.3 2.6 1.6 8.6 2.6 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein DUF4140 PF13600.6 GBG61096.1 - 1 9.8 4.4 0.71 10.3 1.9 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 GBG61096.1 - 2.1 7.6 10.0 3.2 7.0 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CSN5_C PF18323.1 GBG61096.1 - 2.7 9.0 8.6 13 6.8 8.6 2.2 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain LCD1 PF09798.9 GBG61096.1 - 2.9 6.3 8.6 3.8 5.9 8.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein UPF0515 PF15135.6 GBG61096.1 - 5.2 6.3 7.7 0.9 8.8 4.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 DUF659 PF04937.15 GBG61097.1 - 1.5e-14 54.1 0.0 2.6e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61097.1 - 0.075 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region HTH_32 PF13565.6 GBG61097.1 - 0.16 12.6 1.5 0.99 10.1 0.1 2.9 2 0 0 2 2 2 0 Homeodomain-like domain DUF4045 PF13254.6 GBG61100.1 - 3.5 7.2 31.7 4.3 6.9 31.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF659 PF04937.15 GBG61103.1 - 6.9e-29 100.7 0.1 1.2e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2574 PF10836.8 GBG61104.1 - 2 8.3 9.0 22 5.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2574) DUF659 PF04937.15 GBG61106.1 - 6.8e-15 55.2 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) AP2 PF00847.20 GBG61107.1 - 3.1e-07 30.5 0.2 3.1e-07 30.5 0.2 3.0 3 0 0 3 3 2 1 AP2 domain MDM10 PF12519.8 GBG61107.1 - 0.074 11.9 3.2 0.15 10.9 3.2 1.5 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RR_TM4-6 PF06459.12 GBG61107.1 - 0.23 11.3 8.3 0.44 10.3 8.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Velvet PF11754.8 GBG61107.1 - 0.34 10.8 11.8 0.25 11.3 8.7 2.1 2 0 0 2 2 2 0 Velvet factor Tim54 PF11711.8 GBG61107.1 - 1.4 7.7 7.9 2.3 6.9 7.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 GBG61107.1 - 1.5 8.8 9.6 0.12 12.4 4.7 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FAM76 PF16046.5 GBG61107.1 - 1.5 8.1 17.3 0.15 11.4 11.7 1.9 2 0 0 2 2 2 0 FAM76 protein Endostatin PF06482.11 GBG61107.1 - 3.2 7.1 17.8 0.17 11.3 11.8 1.8 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin CPSF100_C PF13299.6 GBG61107.1 - 3.4 7.8 11.3 0.9 9.7 5.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.15 GBG61107.1 - 3.7 6.4 4.2 5.8 5.7 4.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) EOS1 PF12326.8 GBG61107.1 - 6.1 6.7 7.1 0.81 9.6 3.0 1.6 2 0 0 2 2 2 0 N-glycosylation protein TCP PF03634.13 GBG61107.1 - 7.1 7.2 19.3 1.1 9.8 11.0 2.6 2 0 0 2 2 2 0 TCP family transcription factor BORG_CEP PF14957.6 GBG61107.1 - 7.3 7.8 10.4 2.9 9.1 5.1 2.4 2 0 0 2 2 2 0 Cdc42 effector Hydin_ADK PF17213.3 GBG61107.1 - 8.3 6.6 18.7 1.8 8.8 10.7 2.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain EPL1 PF10513.9 GBG61107.1 - 9.5 6.6 18.3 0.71 10.2 12.0 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like BP28CT PF08146.12 GBG61109.1 - 4.8e-42 143.5 0.7 2.7e-40 137.8 0.0 4.2 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 GBG61109.1 - 2.5e-17 63.3 1.3 2.5e-17 63.3 1.3 4.7 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 GBG61109.1 - 0.00034 21.0 12.7 0.072 13.5 0.1 5.5 6 0 0 6 6 6 2 HEAT repeats RTP1_C1 PF10363.9 GBG61109.1 - 0.00042 20.5 5.2 0.31 11.2 0.0 5.0 5 0 0 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 DUF4042 PF13251.6 GBG61109.1 - 0.058 13.1 2.1 1.6 8.4 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) Vac14_Fab1_bd PF12755.7 GBG61109.1 - 0.076 13.6 0.4 11 6.6 0.0 4.1 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Ribosomal_60s PF00428.19 GBG61109.1 - 0.21 12.2 18.0 0.015 15.9 5.5 4.7 4 0 0 4 4 4 0 60s Acidic ribosomal protein HEAT PF02985.22 GBG61109.1 - 0.22 11.9 9.8 24 5.6 0.5 6.8 8 0 0 8 8 8 0 HEAT repeat DUF659 PF04937.15 GBG61114.1 - 4.8e-19 68.7 0.2 7.2e-19 68.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF5568 PF17724.1 GBG61114.1 - 0.11 12.3 0.6 0.26 11.1 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5568) HCV_NS5a PF01506.19 GBG61114.1 - 0.22 11.4 1.4 0.53 10.2 0.2 2.4 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor SDA1 PF05285.12 GBG61115.1 - 0.77 9.1 17.6 1.1 8.6 17.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG61115.1 - 1.8 6.7 21.2 2.4 6.3 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG61115.1 - 2.3 6.4 15.4 3 6.0 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 GBG61115.1 - 8.6 6.0 12.6 16 5.1 12.6 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RT_RNaseH PF17917.1 GBG61118.1 - 4.6e-23 81.5 0.1 7.4e-23 80.8 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61118.1 - 5e-22 77.8 0.1 9e-22 77.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61118.1 - 9.3e-14 51.5 0.1 1.5e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Orf78 PF06024.12 GBG61118.1 - 0.013 15.8 1.9 0.022 15.1 0.2 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Cwf_Cwc_15 PF04889.12 GBG61118.1 - 0.016 15.0 6.6 0.025 14.3 6.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1676 PF07898.13 GBG61118.1 - 0.058 13.4 5.6 0.23 11.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) DUF2615 PF11027.8 GBG61118.1 - 0.24 11.6 6.1 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF2457 PF10446.9 GBG61118.1 - 1.4 8.0 12.7 2 7.5 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 GBG61118.1 - 2.7 7.3 10.9 4 6.7 10.9 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_46 PF01374.18 GBG61119.1 - 1.2e-41 142.7 0.0 1.4e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Glyco_hydro_46 PF01374.18 GBG61120.1 - 2.3e-41 141.7 0.0 2.7e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Glyco_hydro_46 PF01374.18 GBG61121.1 - 1.7e-41 142.2 0.0 1.9e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Nop14 PF04147.12 GBG61122.1 - 1.2 7.2 51.4 1.3 7.1 51.4 1.0 1 0 0 1 1 1 0 Nop14-like family V_ATPase_I PF01496.19 GBG61122.1 - 1.2 6.9 17.2 1.3 6.9 17.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DcuC PF03606.15 GBG61122.1 - 1.3 7.4 3.5 1.9 6.8 3.5 1.5 1 1 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Mpp10 PF04006.12 GBG61122.1 - 1.9 6.8 47.5 2.1 6.7 47.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Presenilin PF01080.17 GBG61122.1 - 2.9 6.5 20.8 3.1 6.5 20.8 1.0 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 GBG61122.1 - 5.3 5.8 14.9 6.1 5.6 14.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CNDH2_C PF16858.5 GBG61122.1 - 7.7 6.3 27.9 8.5 6.2 27.9 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term NPR3 PF03666.13 GBG61122.1 - 8.2 5.1 22.5 9 5.0 22.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CLN3 PF02487.17 GBG61122.1 - 8.3 5.3 8.5 10 5.0 8.5 1.2 1 0 0 1 1 1 0 CLN3 protein CDC45 PF02724.14 GBG61122.1 - 9.7 4.3 41.8 12 4.0 41.8 1.2 1 0 0 1 1 1 0 CDC45-like protein PC4 PF02229.16 GBG61125.1 - 3.6e-25 87.3 0.4 7.9e-25 86.3 0.4 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DEK_C PF08766.11 GBG61125.1 - 4.6e-12 45.7 1.4 9.3e-12 44.7 1.4 1.5 1 0 0 1 1 1 1 DEK C terminal domain eIF-3c_N PF05470.12 GBG61125.1 - 0.076 11.3 4.0 0.088 11.1 4.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NPH3 PF03000.14 GBG61125.1 - 0.15 11.7 4.0 0.2 11.3 4.0 1.4 1 1 0 1 1 1 0 NPH3 family CDC45 PF02724.14 GBG61125.1 - 0.25 9.6 7.8 0.26 9.5 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 GBG61125.1 - 0.27 9.8 3.9 0.28 9.7 3.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF2252 PF10009.9 GBG61125.1 - 0.27 10.2 1.4 0.37 9.8 1.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Zip PF02535.22 GBG61125.1 - 0.29 10.3 1.7 0.3 10.3 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2052 PF09747.9 GBG61125.1 - 0.56 10.3 15.7 0.81 9.8 15.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNA_polI_A34 PF08208.11 GBG61125.1 - 0.77 9.8 17.7 1.2 9.1 17.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 GBG61125.1 - 1.3 7.7 3.4 1.2 7.8 3.4 1.1 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 GBG61125.1 - 2.6 6.5 6.7 3.2 6.2 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3405 PF11885.8 GBG61125.1 - 3.2 6.2 6.5 4.2 5.9 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) RR_TM4-6 PF06459.12 GBG61125.1 - 3.9 7.2 14.1 5.1 6.8 14.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 GBG61125.1 - 5 6.0 15.9 6.9 5.6 15.9 1.1 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 GBG61125.1 - 6.7 5.6 5.9 8.1 5.3 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) U3_snoRNA_assoc PF08297.11 GBG61125.1 - 8.9 7.1 14.9 5.4 7.8 12.1 2.0 2 0 0 2 2 2 0 U3 snoRNA associated zf-CCHC PF00098.23 GBG61129.1 - 0.00022 21.1 0.7 0.00022 21.1 0.7 1.7 2 0 0 2 2 2 1 Zinc knuckle Mo-co_dimer PF03404.16 GBG61129.1 - 0.019 15.0 1.1 0.027 14.5 0.1 1.8 2 0 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain DUF5082 PF16888.5 GBG61129.1 - 0.026 14.8 15.5 0.72 10.1 4.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) RT_RNaseH PF17917.1 GBG61131.1 - 1.5e-21 76.6 0.0 4.2e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61131.1 - 3e-12 46.4 0.0 9e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61131.1 - 1.5e-11 44.2 3.1 2.3e-11 43.6 0.1 2.9 4 0 0 4 4 4 1 Integrase zinc binding domain Chromo PF00385.24 GBG61131.1 - 2e-07 30.8 0.0 5e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG61131.1 - 8.3e-06 25.9 0.1 1.9e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG61131.1 - 0.099 12.5 0.3 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like Ammonium_transp PF00909.21 GBG61132.1 - 1.4e-77 261.1 23.3 4e-50 170.7 11.9 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family Ammonium_transp PF00909.21 GBG61133.1 - 6.7e-104 347.7 36.2 1.4e-59 201.8 13.3 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family Integrase_H2C2 PF17921.1 GBG61134.1 - 6.4e-17 61.4 0.6 1.4e-16 60.4 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG61134.1 - 2.9e-10 40.4 0.1 8e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61134.1 - 8.5e-10 38.5 0.0 1.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG61134.1 - 1.1e-07 32.3 0.0 2.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG61134.1 - 2.9e-07 30.3 0.0 7.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG61134.1 - 8.4e-06 26.3 0.0 3.1e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG61134.1 - 1.7e-05 24.8 0.4 0.0025 17.8 0.0 2.8 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG61134.1 - 0.0087 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG61134.1 - 0.052 13.8 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Dapper PF15268.6 GBG61134.1 - 0.67 8.7 42.9 1.8 7.3 42.9 1.7 1 0 0 1 1 1 0 Dapper Lipase_3 PF01764.25 GBG61135.1 - 3e-24 85.5 0.0 6.6e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) RT_RNaseH PF17917.1 GBG61135.1 - 1.8e-23 82.9 0.0 4.6e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61135.1 - 8.2e-23 80.3 0.0 1.7e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61135.1 - 5.3e-15 55.3 0.1 1.2e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG61135.1 - 9.2e-10 38.4 0.0 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG61135.1 - 0.017 15.4 0.1 0.034 14.4 0.1 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Abhydrolase_6 PF12697.7 GBG61135.1 - 0.075 13.6 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family IMUP PF15761.5 GBG61135.1 - 0.16 12.7 5.1 0.32 11.7 5.1 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein HECW_N PF16562.5 GBG61138.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 AAA PF00004.29 GBG61139.1 - 1.2e-38 132.6 0.0 5.5e-38 130.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG61139.1 - 3.8e-10 39.4 0.1 1.7e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 GBG61139.1 - 5.9e-05 23.1 0.1 0.0003 20.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GBG61139.1 - 0.0001 22.4 0.0 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GBG61139.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG61139.1 - 0.0002 21.6 0.2 0.0083 16.4 0.0 3.1 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 GBG61139.1 - 0.00063 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 GBG61139.1 - 0.00074 19.9 1.8 0.0081 16.6 0.3 3.5 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 GBG61139.1 - 0.0011 18.3 0.5 0.0072 15.6 0.1 2.4 2 1 1 3 3 3 1 TIP49 P-loop domain AAA_2 PF07724.14 GBG61139.1 - 0.0019 18.3 0.0 0.02 15.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Bac_DnaA PF00308.18 GBG61139.1 - 0.0035 17.2 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein Mg_chelatase PF01078.21 GBG61139.1 - 0.0041 16.5 0.1 0.0099 15.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GBG61139.1 - 0.0071 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 GBG61139.1 - 0.016 14.6 0.0 7.6 5.9 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 GBG61139.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 GBG61139.1 - 0.021 14.6 0.0 0.085 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GBG61139.1 - 0.036 14.6 0.0 0.17 12.4 0.0 2.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GBG61139.1 - 0.047 12.9 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Vps4_C PF09336.10 GBG61139.1 - 0.072 13.1 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain PhoH PF02562.16 GBG61139.1 - 0.081 12.4 0.6 0.43 10.0 0.0 2.2 3 0 0 3 3 2 0 PhoH-like protein Sigma54_activ_2 PF14532.6 GBG61139.1 - 0.089 12.9 0.0 13 5.9 0.0 3.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 GBG61139.1 - 0.1 12.2 0.6 1.6 8.3 0.2 2.8 1 1 0 2 2 2 0 AAA domain SH3_12 PF18129.1 GBG61139.1 - 0.12 12.5 0.1 0.73 10.0 0.1 2.4 2 0 0 2 2 1 0 Xrn1 SH3-like domain AFG1_ATPase PF03969.16 GBG61139.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase NACHT PF05729.12 GBG61139.1 - 0.14 12.1 0.0 0.42 10.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 GBG61139.1 - 0.19 12.1 0.0 0.51 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 GBG61140.1 - 1.2e-38 132.6 0.0 5.4e-38 130.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG61140.1 - 3.6e-10 39.5 0.1 1.7e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 GBG61140.1 - 6.1e-05 23.0 0.0 0.00029 20.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG61140.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG61140.1 - 0.00019 21.7 0.2 0.0058 16.9 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GBG61140.1 - 0.00051 20.1 0.0 0.013 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GBG61140.1 - 0.00062 19.6 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 GBG61140.1 - 0.00063 20.2 1.7 0.0077 16.6 0.3 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 GBG61140.1 - 0.0019 18.3 0.0 0.02 15.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 GBG61140.1 - 0.002 17.4 1.9 0.007 15.6 0.1 2.4 2 1 1 3 3 3 1 TIP49 P-loop domain Bac_DnaA PF00308.18 GBG61140.1 - 0.0034 17.3 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein Mg_chelatase PF01078.21 GBG61140.1 - 0.004 16.6 0.1 0.0097 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GBG61140.1 - 0.007 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 GBG61140.1 - 0.016 14.7 0.0 7.4 5.9 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 GBG61140.1 - 0.017 14.6 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 GBG61140.1 - 0.033 14.7 0.0 0.17 12.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 GBG61140.1 - 0.037 14.2 0.0 12 6.0 0.0 3.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 GBG61140.1 - 0.037 13.8 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GBG61140.1 - 0.047 12.8 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 GBG61140.1 - 0.07 12.6 0.1 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Vps4_C PF09336.10 GBG61140.1 - 0.07 13.1 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 GBG61140.1 - 0.11 12.1 0.6 1.5 8.3 0.2 2.7 1 1 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 GBG61140.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase SH3_12 PF18129.1 GBG61140.1 - 0.13 12.4 0.1 0.71 10.0 0.1 2.3 2 0 0 2 2 2 0 Xrn1 SH3-like domain NACHT PF05729.12 GBG61140.1 - 0.13 12.1 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 GBG61140.1 - 0.19 12.1 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Integrase_H2C2 PF17921.1 GBG61141.1 - 4.9e-14 52.2 0.8 1.7e-13 50.5 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG61141.1 - 1.6e-11 44.5 0.0 4.9e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG61141.1 - 4.2e-11 42.6 0.0 8.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG61141.1 - 0.0035 17.3 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG61141.1 - 0.018 15.6 0.0 0.036 14.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG61141.1 - 0.052 13.8 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG61141.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF2890 PF11081.8 GBG61141.1 - 2.5 8.2 7.3 0.3 11.2 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Mito_carr PF00153.27 GBG61142.1 - 9.4e-62 205.0 0.4 1.1e-19 70.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein FTR PF01913.18 GBG61142.1 - 0.092 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase TatC PF00902.18 GBG61143.1 - 2.9e-59 200.4 11.3 3.4e-59 200.1 11.3 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF2919 PF11143.8 GBG61143.1 - 0.0088 16.4 3.2 0.01 16.2 2.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2919) NdhL PF10716.9 GBG61143.1 - 6.6 6.8 8.2 0.86 9.6 3.4 1.9 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit NdhL PF10716.9 GBG61144.1 - 1.2e-08 34.8 2.2 1.9e-08 34.2 2.2 1.2 1 0 0 1 1 1 1 NADH dehydrogenase transmembrane subunit Cyt-b5 PF00173.28 GBG61145.1 - 8.5e-10 38.7 0.3 1.4e-09 37.9 0.3 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PfkB PF00294.24 GBG61146.1 - 2.7e-41 141.9 1.7 5.2e-26 91.7 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MoCF_biosynth PF00994.24 GBG61146.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.6 1 1 0 1 1 1 0 Probable molybdopterin binding domain Plavaka PF18759.1 GBG61147.1 - 2.2e-11 43.6 0.1 3e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-ANAPC11 PF12861.7 GBG61147.1 - 0.038 14.0 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3395 PF11875.8 GBG61147.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Pkinase PF00069.25 GBG61148.1 - 2.2e-78 263.3 0.0 3.4e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61148.1 - 1.7e-41 142.3 0.0 2.4e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 GBG61148.1 - 2.9e-07 31.0 0.7 0.00037 20.9 0.0 3.5 2 1 1 3 3 3 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 GBG61148.1 - 3.7e-07 29.8 0.0 6.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 GBG61148.1 - 7e-07 28.9 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 UBA PF00627.31 GBG61148.1 - 1.2e-05 25.0 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_2 PF08587.11 GBG61148.1 - 1.4e-05 25.1 0.3 2.7e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.22 GBG61148.1 - 0.0014 18.3 0.2 0.0028 17.3 0.2 1.4 1 0 0 1 1 1 1 RIO1 family UBA_3 PF09288.10 GBG61148.1 - 0.0016 18.2 0.1 0.0016 18.2 0.1 2.1 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain DUF1421 PF07223.11 GBG61148.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Haspin_kinase PF12330.8 GBG61148.1 - 0.24 10.3 0.1 0.35 9.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 GBG61149.1 - 2.2e-78 263.2 0.0 3.2e-78 262.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61149.1 - 1.6e-41 142.3 0.0 2.3e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 GBG61149.1 - 2.7e-10 40.7 0.6 3.7e-07 30.6 0.0 3.4 2 1 1 3 3 3 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 GBG61149.1 - 3.6e-07 29.8 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 GBG61149.1 - 6.8e-07 29.0 0.0 1.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 UBA PF00627.31 GBG61149.1 - 1.2e-05 25.1 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_2 PF08587.11 GBG61149.1 - 1.3e-05 25.2 0.3 2.7e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.22 GBG61149.1 - 0.0014 18.3 0.2 0.0027 17.3 0.2 1.4 1 0 0 1 1 1 1 RIO1 family UBA_3 PF09288.10 GBG61149.1 - 0.0015 18.3 0.1 0.0015 18.3 0.1 2.1 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain DUF1421 PF07223.11 GBG61149.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Haspin_kinase PF12330.8 GBG61149.1 - 0.24 10.3 0.1 0.34 9.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain BAF1_ABF1 PF04684.13 GBG61150.1 - 1.2 8.1 8.8 1.5 7.8 8.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-CCHC PF00098.23 GBG61151.1 - 1.3e-06 28.2 3.5 2.6e-06 27.3 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG61151.1 - 0.094 12.7 0.7 0.23 11.5 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 GBG61151.1 - 4.6 5.9 4.9 6.1 5.5 4.9 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 GBG61152.1 - 0.02 13.4 1.7 0.021 13.4 1.7 1.1 1 0 0 1 1 1 0 Macoilin family Ashwin PF15323.6 GBG61152.1 - 4.6 7.2 7.8 6.8 6.6 7.8 1.2 1 0 0 1 1 1 0 Developmental protein Rrn6 PF10214.9 GBG61153.1 - 0.19 10.2 17.7 0.22 10.0 17.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CCDC106 PF15794.5 GBG61153.1 - 0.55 9.9 16.4 0.74 9.5 16.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 BUD22 PF09073.10 GBG61153.1 - 4.5 6.5 44.6 4.9 6.4 44.6 1.1 1 0 0 1 1 1 0 BUD22 DUF3136 PF11334.8 GBG61154.1 - 0.11 12.3 0.4 25 4.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3136) TcdA_TcdB PF12919.7 GBG61154.1 - 0.17 11.1 0.1 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain RT_RNaseH_2 PF17919.1 GBG61155.1 - 1.8e-33 114.5 0.0 3.2e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61155.1 - 1.2e-29 102.7 0.0 2.5e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_C26 PF07722.13 GBG61155.1 - 2.6e-15 56.8 0.0 9.4e-15 54.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 Integrase_H2C2 PF17921.1 GBG61155.1 - 7.6e-12 45.2 0.0 1.5e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain GATase PF00117.28 GBG61155.1 - 0.00082 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DUF659 PF04937.15 GBG61157.1 - 2e-14 53.7 0.0 4.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61157.1 - 3.6e-07 29.9 0.0 7.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CBP_BcsG PF11658.8 GBG61158.1 - 0.0058 15.1 0.2 0.0058 15.1 0.2 1.4 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsG Sigma70_ner PF04546.13 GBG61158.1 - 0.0063 16.4 2.1 0.0063 16.4 2.1 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region GP67 PF17634.2 GBG61158.1 - 0.022 15.1 20.5 0.03 14.7 20.5 1.2 1 0 0 1 1 1 0 Gene product 67 PPP4R2 PF09184.11 GBG61158.1 - 0.023 14.3 2.5 0.022 14.3 2.5 1.1 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.11 GBG61158.1 - 0.4 10.7 7.0 0.51 10.3 7.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 GBG61158.1 - 1.3 7.5 12.5 1.3 7.4 12.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CytochromB561_N PF09786.9 GBG61158.1 - 3 6.7 4.4 3.4 6.6 4.4 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal NOA36 PF06524.12 GBG61158.1 - 3.9 6.7 23.5 4.5 6.5 23.5 1.1 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 GBG61158.1 - 5.1 6.2 9.3 5.5 6.0 9.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAM176 PF14851.6 GBG61158.1 - 5.2 6.7 14.6 0.081 12.6 5.9 2.2 1 1 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 GBG61158.1 - 7.2 7.1 31.8 13 6.3 31.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MIP PF00230.20 GBG61160.1 - 2.5e-65 220.4 15.9 3.6e-65 219.9 15.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF659 PF04937.15 GBG61160.1 - 1.8e-14 53.8 0.0 3.2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF908 PF06012.12 GBG61160.1 - 0.26 10.6 0.5 0.4 10.0 0.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PRIMA1 PF16101.5 GBG61160.1 - 5 7.2 5.6 52 3.9 5.6 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Na_trans_assoc PF06512.13 GBG61161.1 - 0.0071 16.6 12.2 0.0093 16.3 12.2 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated BUD22 PF09073.10 GBG61161.1 - 0.73 9.1 19.4 0.89 8.8 19.4 1.1 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.10 GBG61161.1 - 0.78 9.1 13.6 1 8.6 13.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 GBG61161.1 - 2.6 7.4 26.5 3.4 7.0 26.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG61161.1 - 2.9 6.1 17.9 4 5.6 17.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GBG61161.1 - 6.3 5.1 25.2 8.3 4.7 25.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG61161.1 - 6.9 4.7 23.8 9.1 4.3 23.8 1.1 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 GBG61161.1 - 9.3 5.2 11.4 12 4.8 11.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MIP PF00230.20 GBG61162.1 - 7.6e-68 228.6 15.6 8.8e-68 228.4 15.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF659 PF04937.15 GBG61163.1 - 1.7e-38 131.8 0.0 5.8e-38 130.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG61163.1 - 0.34 10.9 9.6 0.074 13.0 5.3 2.3 2 0 0 2 2 2 0 AT hook motif MIP PF00230.20 GBG61164.1 - 4e-67 226.2 15.1 4.7e-67 226.0 15.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 GBG61166.1 - 1.6e-64 217.7 17.5 2e-64 217.4 17.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein zf-CCHC PF00098.23 GBG61167.1 - 1.4e-08 34.5 1.1 1.4e-08 34.5 1.1 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG61167.1 - 0.029 14.1 0.2 0.059 13.1 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle FTA4 PF13093.6 GBG61167.1 - 0.075 12.9 8.5 0.099 12.5 8.5 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Atrophin-1 PF03154.15 GBG61167.1 - 0.11 10.7 3.7 0.14 10.5 3.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF3584 PF12128.8 GBG61167.1 - 0.33 8.4 16.8 0.41 8.1 16.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1943 PF09172.11 GBG61167.1 - 0.78 8.9 6.4 1.1 8.4 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) CTNNB1_binding PF08347.11 GBG61167.1 - 1.1 9.4 5.6 1.7 8.8 5.6 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding CENP-Q PF13094.6 GBG61167.1 - 1.8 8.7 16.6 0.57 10.4 4.7 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CAF-1_p150 PF11600.8 GBG61167.1 - 1.9 8.1 32.8 0.24 11.1 23.4 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4407 PF14362.6 GBG61167.1 - 4.1 6.7 12.0 5.7 6.2 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG61168.1 - 3.4e-28 98.7 0.1 7.8e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61168.1 - 1e-13 51.2 0.0 2.7e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61168.1 - 4.3e-05 23.8 0.0 0.00013 22.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG61168.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease FAM76 PF16046.5 GBG61168.1 - 0.089 12.1 6.4 0.15 11.4 6.4 1.3 1 0 0 1 1 1 0 FAM76 protein Filo_VP35 PF02097.15 GBG61168.1 - 0.14 11.2 0.5 0.28 10.2 0.5 1.4 1 0 0 1 1 1 0 Filoviridae VP35 Zip PF02535.22 GBG61169.1 - 8.3e-30 104.1 12.5 2.9e-29 102.3 12.5 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3413 PF11893.8 GBG61169.1 - 0.76 8.9 6.2 0.21 10.7 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) YjeF_N PF03853.15 GBG61170.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus DDE_Tnp_4 PF13359.6 GBG61171.1 - 1.6e-25 89.6 0.0 2.2e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61171.1 - 1.2e-16 60.9 0.0 2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61171.1 - 0.02 14.5 0.5 3.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain CENP-N PF05238.13 GBG61172.1 - 0.15 11.3 8.2 0.16 11.2 8.2 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like RNA_polI_A34 PF08208.11 GBG61172.1 - 0.2 11.7 16.9 0.27 11.3 16.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SET PF00856.28 GBG61172.1 - 0.22 11.9 4.8 0.41 11.0 4.8 1.4 1 1 0 1 1 1 0 SET domain Tim54 PF11711.8 GBG61172.1 - 0.33 9.7 14.6 0.45 9.2 14.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S64 PF08192.11 GBG61172.1 - 0.51 8.8 8.9 0.6 8.5 8.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 GBG61172.1 - 0.59 8.8 18.1 0.69 8.6 18.1 1.0 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG61172.1 - 0.67 8.1 26.9 0.81 7.8 26.9 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG61172.1 - 0.85 9.4 24.0 1.1 9.0 24.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 GBG61172.1 - 0.94 8.6 9.3 1.1 8.4 9.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter POP1 PF06978.11 GBG61172.1 - 1.1 9.2 10.0 1.4 8.9 10.0 1.1 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 SAPS PF04499.15 GBG61172.1 - 1.2 7.8 16.0 1.5 7.5 16.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 GBG61172.1 - 3.5 6.3 18.8 4.7 5.9 18.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FemAB PF02388.16 GBG61172.1 - 3.9 6.2 12.4 4.9 5.9 12.4 1.1 1 0 0 1 1 1 0 FemAB family FAM60A PF15396.6 GBG61172.1 - 3.9 7.4 11.8 5 7.1 11.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.14 GBG61172.1 - 7 4.8 24.7 8.4 4.6 24.7 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG61172.1 - 8.4 5.7 30.1 11 5.4 30.1 1.1 1 0 0 1 1 1 0 SDA1 DUF2151 PF10221.9 GBG61172.1 - 9.5 4.7 14.5 11 4.4 14.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator LRR_6 PF13516.6 GBG61173.1 - 0.011 15.7 0.5 20 5.6 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat SDA1 PF05285.12 GBG61174.1 - 0.24 10.8 18.2 0.33 10.3 18.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG61174.1 - 0.33 9.2 13.3 0.44 8.8 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.8 GBG61174.1 - 0.85 8.5 7.2 1.4 7.8 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BUD22 PF09073.10 GBG61174.1 - 0.86 8.9 15.8 1.1 8.5 15.8 1.1 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 GBG61174.1 - 0.91 8.5 6.4 1.2 8.1 6.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG61174.1 - 2 6.5 21.9 2.8 6.0 21.9 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG61174.1 - 2 6.9 20.1 2.8 6.4 20.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) APG6_N PF17675.1 GBG61176.1 - 0.005 17.4 0.8 0.005 17.4 0.8 4.2 3 1 1 4 4 4 1 Apg6 coiled-coil region RVP_2 PF08284.11 GBG61176.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease TadF PF16964.5 GBG61176.1 - 1.1 9.0 3.4 2.5 7.8 3.4 1.6 1 0 0 1 1 1 0 Putative tight adherence pilin protein F Drc1-Sld2 PF11719.8 GBG61177.1 - 2.5e-06 27.3 3.9 1.7e-05 24.6 3.6 2.0 1 1 0 1 1 1 1 DNA replication and checkpoint protein Bromodomain PF00439.25 GBG61179.1 - 2.6e-10 40.3 0.0 5.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain ARID PF01388.21 GBG61179.1 - 0.00072 20.2 0.2 0.0029 18.2 0.2 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Clathrin PF00637.20 GBG61180.1 - 1.5e-05 24.9 0.7 0.0066 16.3 0.0 3.1 2 2 1 3 3 3 2 Region in Clathrin and VPS TPR_14 PF13428.6 GBG61180.1 - 9.6e-05 22.9 0.5 1.7 9.6 0.0 5.1 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG61180.1 - 0.00017 21.4 1.7 2.2 8.5 0.2 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 GBG61180.1 - 0.00072 18.7 0.3 0.0013 17.9 0.3 1.3 1 0 0 1 1 1 1 Coatomer WD associated region DZR PF12773.7 GBG61180.1 - 0.017 15.1 7.0 0.55 10.3 7.0 2.6 1 1 0 1 1 1 0 Double zinc ribbon TPR_8 PF13181.6 GBG61180.1 - 0.019 15.1 2.7 1.5 9.2 0.5 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG61180.1 - 0.16 12.6 0.4 48 4.7 0.2 3.5 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG61180.1 - 0.53 10.8 2.7 3 8.4 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG61180.1 - 0.7 10.2 4.7 16 5.9 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG61180.1 - 1.2 9.1 6.0 8.3 6.4 0.4 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG61180.1 - 1.6 9.0 9.0 5.5 7.3 0.3 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat zf-C2HC5 PF06221.13 GBG61180.1 - 3.9 7.5 10.7 22 5.2 1.8 3.7 1 1 2 3 3 3 0 Putative zinc finger motif, C2HC5-type PGA_cap PF09587.10 GBG61181.1 - 3.1e-73 246.4 0.0 5e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap rve PF00665.26 GBG61182.1 - 2.8e-11 43.7 0.1 6.1e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG61182.1 - 0.014 15.6 0.4 0.1 12.9 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG61182.1 - 0.02 14.8 1.3 0.041 13.8 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1564 PF07600.11 GBG61182.1 - 0.065 12.9 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Ecl1 PF12855.7 GBG61182.1 - 7 7.8 13.6 1.5 10.0 3.5 3.1 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins Methyltransf_PK PF05891.12 GBG61183.1 - 4.4e-81 271.6 0.0 7.2e-81 270.9 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 GBG61183.1 - 2.8e-22 79.3 0.0 4.9e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 GBG61183.1 - 1.6e-11 44.8 0.1 3.3e-09 37.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG61183.1 - 4.2e-07 30.5 0.0 6.1e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG61183.1 - 1.2e-05 25.9 0.0 0.00027 21.6 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG61183.1 - 1.8e-05 24.6 0.0 0.00051 19.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GBG61183.1 - 0.021 14.2 1.3 0.027 13.9 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) RVT_1 PF00078.27 GBG61184.1 - 3.1e-55 187.1 0.0 7.1e-34 117.3 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61184.1 - 4.6e-28 97.2 0.0 9.2e-15 54.5 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase WD40_3 PF15911.5 GBG61184.1 - 6e-16 58.2 0.1 4.8e-14 52.1 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat RT_RNaseH PF17917.1 GBG61184.1 - 8.3e-12 45.3 0.0 3.5e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG61184.1 - 2.4e-11 43.6 0.0 5.5e-08 32.7 0.0 3.0 3 0 0 3 3 3 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61184.1 - 2.2e-08 34.6 0.0 2.3e-07 31.4 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61184.1 - 7.2e-06 26.5 0.0 3.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG61184.1 - 4.7e-05 23.6 0.2 0.78 10.1 0.1 3.1 2 0 0 2 2 2 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG61184.1 - 0.0029 17.4 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease SlyX PF04102.12 GBG61184.1 - 0.071 13.7 0.2 0.071 13.7 0.2 4.1 7 0 0 7 7 7 0 SlyX RT_RNaseH_2 PF17919.1 GBG61185.1 - 4.4e-35 119.7 0.0 1e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61185.1 - 4.8e-31 107.2 0.0 8.9e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61185.1 - 2e-23 83.1 0.0 3.4e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61185.1 - 1.7e-15 57.3 0.1 9.5e-15 54.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG61185.1 - 5.2e-08 32.9 0.1 1.1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG61185.1 - 6.6e-05 23.0 0.2 0.0002 21.5 0.2 1.8 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 GBG61185.1 - 0.1 12.4 0.0 0.32 10.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG61186.1 - 2.4e-33 115.5 0.1 3.6e-33 115.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG61186.1 - 0.00031 20.4 0.1 0.00063 19.5 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61186.1 - 0.0085 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein ANAPC4_WD40 PF12894.7 GBG61186.1 - 0.047 14.0 0.1 0.39 11.0 0.0 2.2 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DEC-1_N PF04625.13 GBG61190.1 - 3.2 6.7 8.2 7.4 5.5 8.2 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Tom22 PF04281.13 GBG61191.1 - 0.04 13.7 0.3 0.04 13.7 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Presenilin PF01080.17 GBG61191.1 - 0.46 9.2 3.0 0.63 8.7 3.0 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 GBG61191.1 - 1.4 8.6 4.2 2.1 8.0 1.2 2.1 2 0 0 2 2 2 0 Connexin RPN2_C PF18004.1 GBG61191.1 - 6.7 6.6 9.2 9.4 6.1 5.1 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain MMS1_N PF10433.9 GBG61192.1 - 4e-110 368.8 0.0 5.7e-110 368.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GBG61192.1 - 1.3e-79 267.8 0.0 2.5e-79 266.9 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region CN_hydrolase PF00795.22 GBG61195.1 - 3e-35 121.8 0.0 4e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 GBG61195.1 - 1.4e-25 89.9 0.0 2.4e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.21 GBG61195.1 - 0.045 13.4 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase WAPL PF07814.13 GBG61196.1 - 8.7e-62 209.0 5.4 1.8e-40 138.9 0.0 4.4 3 1 0 3 3 3 3 Wings apart-like protein regulation of heterochromatin Atypical_Card PF18461.1 GBG61196.1 - 0.051 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Atypical caspase recruitment domain Adap_comp_sub PF00928.21 GBG61197.1 - 2.9e-16 59.6 0.0 3.9e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family CDC45 PF02724.14 GBG61197.1 - 2.6 6.2 4.8 4.5 5.4 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG61197.1 - 5.5 6.2 10.5 0.34 10.2 2.6 2.0 2 0 0 2 2 2 0 NOA36 protein F-box-like PF12937.7 GBG61198.1 - 6.5e-05 22.8 0.2 0.00011 22.0 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG61198.1 - 0.0026 17.6 0.9 0.0065 16.3 0.9 1.7 1 1 0 1 1 1 1 F-box domain SH3_9 PF14604.6 GBG61198.1 - 0.023 14.5 0.1 0.29 11.0 0.1 2.8 3 0 0 3 3 3 0 Variant SH3 domain TMEM51 PF15345.6 GBG61198.1 - 0.029 14.2 0.9 0.067 13.0 0.7 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 Eapp_C PF10238.9 GBG61198.1 - 0.14 12.3 2.2 0.29 11.2 0.1 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF3104 PF11302.8 GBG61198.1 - 0.14 11.9 0.6 0.93 9.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3104) BUD22 PF09073.10 GBG61198.1 - 1.3 8.3 22.1 2.7 7.2 22.1 1.6 1 0 0 1 1 1 0 BUD22 Drc1-Sld2 PF11719.8 GBG61198.1 - 1.5 8.3 11.0 2.5 7.6 11.0 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Presenilin PF01080.17 GBG61198.1 - 2 7.1 9.7 3.2 6.4 9.7 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG61198.1 - 3.8 6.2 8.4 5.1 5.8 8.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF3_subunit PF08597.10 GBG61198.1 - 4.1 7.2 22.9 8.3 6.2 22.9 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit V_ATPase_I PF01496.19 GBG61198.1 - 7.6 4.3 7.4 11 3.8 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC73 PF15818.5 GBG61199.1 - 0.85 7.4 6.1 0.97 7.2 6.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family Pentapeptide PF00805.22 GBG61201.1 - 9e-20 70.0 14.3 2.5e-08 33.4 0.2 3.3 2 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 GBG61201.1 - 1.8e-10 40.8 6.7 1e-05 25.6 4.3 3.0 1 1 0 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 GBG61201.1 - 7.3e-08 32.5 1.8 2.2e-06 27.8 0.2 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) DUF5052 PF16475.5 GBG61203.1 - 0.14 11.8 2.9 0.21 11.2 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) Myb_DNA-bind_4 PF13837.6 GBG61204.1 - 9.3e-07 29.1 3.8 9.3e-07 29.1 3.8 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG61204.1 - 0.00032 20.7 2.7 0.0011 19.0 2.2 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG61204.1 - 0.0034 17.6 1.5 0.0059 16.8 1.5 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG61204.1 - 0.026 14.8 1.4 0.026 14.8 1.4 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Drc1-Sld2 PF11719.8 GBG61204.1 - 0.036 13.6 0.5 0.054 13.0 0.5 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Myb_DNA-binding PF00249.31 GBG61204.1 - 0.037 14.2 0.6 0.081 13.1 0.6 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG61205.1 - 4.1e-31 107.8 0.0 1.2e-30 106.3 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61205.1 - 7.4e-15 55.1 0.0 1.2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61205.1 - 6e-06 26.0 0.3 0.088 12.4 0.2 2.8 3 0 0 3 3 3 2 Transposase DDE domain PLAC8 PF04749.17 GBG61206.1 - 2.5e-24 86.1 18.3 3.5e-24 85.7 18.3 1.2 1 0 0 1 1 1 1 PLAC8 family YGGT PF02325.17 GBG61208.1 - 8.1e-17 61.4 3.0 1.9e-16 60.3 3.0 1.5 1 0 0 1 1 1 1 YGGT family DUF3945 PF13101.6 GBG61208.1 - 0.03 14.1 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) TPR_14 PF13428.6 GBG61209.1 - 2.2e-05 24.9 7.7 0.0065 17.2 1.7 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG61209.1 - 4.2e-05 23.4 3.0 0.025 14.7 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG61209.1 - 0.0002 21.0 2.7 0.14 12.0 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG61209.1 - 0.00077 19.9 2.9 0.0017 18.8 2.9 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GBG61209.1 - 0.00096 19.2 2.5 0.94 9.9 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG61209.1 - 0.0012 19.1 2.2 0.0064 16.8 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG61209.1 - 0.021 15.5 4.1 0.043 14.5 3.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG61209.1 - 2.6 8.4 5.7 9.2 6.6 2.7 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.29 GBG61210.1 - 1.9e-46 158.0 0.0 1.2e-45 155.4 0.0 2.1 1 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG61210.1 - 1.8e-32 112.0 0.1 6.2e-32 110.2 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG61210.1 - 2.2e-05 24.6 1.0 0.00042 20.4 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GBG61210.1 - 0.0024 18.2 0.0 3.4 8.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain TFIIA PF03153.13 GBG61211.1 - 0.96 9.4 12.7 1.3 8.9 12.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Y_phosphatase2 PF03162.13 GBG61212.1 - 1.2e-29 103.0 0.0 3.2e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family Thioredoxin PF00085.20 GBG61212.1 - 8.4e-05 22.5 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Y_phosphatase PF00102.27 GBG61212.1 - 0.051 13.1 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GBG61212.1 - 0.075 13.0 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF3403 PF11883.8 GBG61212.1 - 0.23 11.6 0.9 0.38 10.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) HAUS4 PF14735.6 GBG61213.1 - 3.6e-59 200.3 2.4 5.5e-59 199.7 2.4 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 ANAPC4_WD40 PF12894.7 GBG61213.1 - 2.5e-07 30.9 0.0 0.0071 16.6 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GBG61213.1 - 0.00036 21.3 2.0 41 5.3 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Syntaxin-6_N PF09177.11 GBG61213.1 - 0.21 12.2 0.9 0.53 10.9 0.1 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RVT_1 PF00078.27 GBG61214.1 - 6.7e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Carb_kinase PF01256.17 GBG61214.1 - 0.031 13.7 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate kinase RT_RNaseH PF17917.1 GBG61215.1 - 7.5e-19 68.0 0.0 1.8e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61215.1 - 6.3e-18 64.7 0.0 1.9e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG61215.1 - 3.2e-07 30.8 0.0 8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61215.1 - 0.00022 21.8 0.0 0.00056 20.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG61215.1 - 0.018 14.8 0.2 0.033 14.0 0.2 1.4 1 0 0 1 1 1 0 Aspartyl protease GAD-like PF08887.11 GBG61215.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 GAD-like domain RVP PF00077.20 GBG61215.1 - 0.19 12.1 0.0 0.61 10.4 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease TMPIT PF07851.13 GBG61216.1 - 1.3e-38 133.1 0.0 1.8e-33 116.2 0.0 2.1 2 0 0 2 2 2 2 TMPIT-like protein DUF2514 PF10721.9 GBG61216.1 - 0.034 14.2 5.2 0.066 13.2 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) THOC7 PF05615.13 GBG61216.1 - 0.084 13.2 0.5 0.18 12.1 0.5 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 DivIC PF04977.15 GBG61216.1 - 0.13 12.1 0.5 0.43 10.4 0.5 1.9 1 0 0 1 1 1 0 Septum formation initiator DUF1771 PF08590.10 GBG61216.1 - 0.15 12.5 3.0 0.41 11.1 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) HALZ PF02183.18 GBG61216.1 - 0.21 11.9 0.3 0.42 10.9 0.3 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Plavaka PF18759.1 GBG61217.1 - 1.6e-26 93.3 0.1 2.9e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Plavaka transposase RRM_1 PF00076.22 GBG61218.1 - 7.3e-47 157.1 0.3 7.8e-16 57.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 GBG61218.1 - 6e-18 65.2 0.1 4.4e-17 62.4 0.0 2.6 2 0 0 2 2 2 1 SPOC domain RRM_occluded PF16842.5 GBG61218.1 - 7.9e-10 38.5 0.0 0.00039 20.2 0.0 3.5 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_7 PF16367.5 GBG61218.1 - 0.00012 22.2 0.0 0.65 10.2 0.0 4.1 3 0 0 3 3 3 2 RNA recognition motif Red1 PF07964.11 GBG61219.1 - 0.076 11.3 22.3 0.073 11.3 22.3 1.2 1 0 0 1 1 1 0 Rec10 / Red1 DUF936 PF06075.12 GBG61219.1 - 0.79 8.6 18.6 0.77 8.6 18.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SLC12 PF03522.15 GBG61219.1 - 1.4 7.9 19.2 1.5 7.8 19.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF2151 PF10221.9 GBG61219.1 - 1.6 7.2 22.9 1.8 7.1 22.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SID-1_RNA_chan PF13965.6 GBG61219.1 - 1.7 7.0 10.9 1.6 7.1 10.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MCM_bind PF09739.9 GBG61219.1 - 3.4 6.0 18.9 3.7 5.9 18.9 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA_11 PF13086.6 GBG61219.1 - 3.9 7.2 17.9 4.7 6.9 17.9 1.2 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 GBG61219.1 - 4.1 7.4 11.1 4.7 7.2 11.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop53 PF07767.11 GBG61219.1 - 4.7 6.5 56.2 11 5.3 56.2 1.6 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Hid1 PF12722.7 GBG61219.1 - 4.8 5.2 18.1 5.3 5.0 18.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mpp10 PF04006.12 GBG61219.1 - 7.1 4.9 55.5 9.8 4.5 55.5 1.2 1 0 0 1 1 1 0 Mpp10 protein tRNA-synt_2d PF01409.20 GBG61220.1 - 4.8e-49 167.0 0.2 8.8e-49 166.2 0.2 1.4 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 GBG61220.1 - 8.3e-24 83.8 0.0 2.2e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF4407 PF14362.6 GBG61221.1 - 0.081 12.3 15.5 0.56 9.5 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1515 PF07439.11 GBG61221.1 - 0.098 12.7 7.1 0.13 12.2 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) DivIC PF04977.15 GBG61221.1 - 1.5 8.6 0.0 1.5 8.6 0.0 5.5 3 1 2 5 5 5 0 Septum formation initiator CdiI_2 PF18593.1 GBG61221.1 - 3.6 8.3 7.0 12 6.6 1.0 3.1 3 1 0 3 3 3 0 CdiI immunity protein TPR_MLP1_2 PF07926.12 GBG61221.1 - 3.9 7.5 31.4 3.7 7.6 3.2 4.3 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein DUF4746 PF15928.5 GBG61222.1 - 2.4 7.5 8.8 3.3 7.1 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 GBG61222.1 - 7 4.8 7.6 8.5 4.5 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG61222.1 - 9.3 5.5 12.7 12 5.2 12.7 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG61222.1 - 9.3 4.3 13.9 12 3.9 13.9 1.0 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG61223.1 - 2.4e-26 92.6 0.0 4e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61223.1 - 6.4e-22 77.5 0.0 5.9e-16 58.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61223.1 - 1.7e-16 60.0 1.0 7.2e-16 58.0 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG61223.1 - 3.6e-12 46.5 0.4 2.2e-11 44.0 0.1 2.5 3 0 0 3 3 3 1 Integrase core domain RT_RNaseH PF17917.1 GBG61223.1 - 2.6e-09 37.3 0.0 6.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG61223.1 - 3.3e-05 24.0 0.0 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG61225.1 - 1.5e-29 102.0 0.0 1.4e-15 57.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61225.1 - 5.6e-27 94.1 0.0 1.4e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61225.1 - 4.7e-14 52.2 0.0 1.1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61225.1 - 5.8e-13 49.1 0.1 3.9e-12 46.4 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.27 GBG61225.1 - 1.8e-12 47.2 0.2 2.8e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG61225.1 - 0.00074 19.7 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger NTPase_1 PF03266.15 GBG61226.1 - 5.5e-32 111.0 0.0 6.5e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 GBG61226.1 - 1.9e-06 28.3 0.0 3.5e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GBG61226.1 - 4e-05 23.9 0.1 0.00012 22.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 GBG61226.1 - 0.00034 21.1 0.1 0.00048 20.6 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GBG61226.1 - 0.00044 20.0 0.0 0.00056 19.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GBG61226.1 - 0.0041 17.1 0.1 0.0076 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 GBG61226.1 - 0.008 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DUF2075 PF09848.9 GBG61226.1 - 0.0088 15.3 0.2 0.011 15.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 GBG61226.1 - 0.012 16.2 0.1 0.017 15.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GBG61226.1 - 0.013 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 GBG61226.1 - 0.014 14.9 0.1 0.027 14.0 0.1 1.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_32 PF13654.6 GBG61226.1 - 0.014 14.2 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG61226.1 - 0.016 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 GBG61226.1 - 0.024 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 GBG61226.1 - 0.036 14.1 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 GBG61226.1 - 0.037 13.6 0.1 0.056 13.0 0.1 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 GBG61226.1 - 0.038 13.7 0.1 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 GBG61226.1 - 0.042 13.1 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 GBG61226.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GBG61226.1 - 0.062 13.5 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GBG61226.1 - 0.069 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 GBG61226.1 - 0.078 13.4 0.0 0.22 11.9 0.0 1.7 2 1 1 3 3 2 0 RNA helicase TniB PF05621.11 GBG61226.1 - 0.079 12.4 0.0 9.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein RuvB_N PF05496.12 GBG61226.1 - 0.13 12.0 0.1 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain KAP_NTPase PF07693.14 GBG61226.1 - 0.14 11.4 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.6 GBG61226.1 - 0.14 12.5 0.2 0.17 12.2 0.2 1.5 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 GBG61226.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Viral_helicase1 PF01443.18 GBG61226.1 - 0.19 11.4 0.1 0.32 10.7 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Myb_DNA-binding PF00249.31 GBG61229.1 - 0.002 18.3 0.1 0.0043 17.2 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG61230.1 - 0.0018 18.4 0.1 0.0041 17.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF659 PF04937.15 GBG61231.1 - 5.7e-22 78.2 0.2 8.5e-22 77.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG61232.1 - 2e-34 117.6 0.0 5.3e-34 116.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61232.1 - 1.3e-29 102.6 0.0 3e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61232.1 - 1.5e-27 96.5 0.0 2.7e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG61232.1 - 1.3e-17 63.7 0.2 2.7e-17 62.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61232.1 - 3e-11 43.5 0.0 7.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Nuc_deoxyrib_tr PF05014.15 GBG61233.1 - 7.4e-23 81.0 35.3 0.74 9.8 0.0 21.1 13 6 4 20 20 20 10 Nucleoside 2-deoxyribosyltransferase BRCA2 PF00634.18 GBG61233.1 - 2.9e-17 62.0 33.9 13 5.6 0.0 23.5 30 0 0 30 30 30 4 BRCA2 repeat Acetyltransf_18 PF18014.1 GBG61233.1 - 2.1e-08 34.1 8.9 6.8 6.6 0.0 12.3 11 5 4 15 15 15 1 Acetyltransferase (GNAT) domain Con-6 PF10346.9 GBG61233.1 - 7.8 6.6 8.1 7 6.8 0.0 4.5 4 0 0 4 4 4 0 Conidiation protein 6 BRCA-2_OB1 PF09103.10 GBG61234.1 - 1.7e-35 121.7 0.0 4e-35 120.4 0.0 1.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 GBG61234.1 - 5.2e-18 65.4 0.2 5.2e-18 65.4 0.2 2.1 2 0 0 2 2 2 1 BRCA2, helical rve PF00665.26 GBG61234.1 - 1.9e-06 28.0 0.1 7.7e-06 26.1 0.1 2.0 1 0 0 1 1 1 1 Integrase core domain FANCM-MHF_bd PF16783.5 GBG61234.1 - 0.17 12.0 2.0 0.55 10.3 2.0 1.9 1 0 0 1 1 1 0 FANCM to MHF binding domain RVT_1 PF00078.27 GBG61235.1 - 6.1e-37 127.3 0.1 9.6e-37 126.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61235.1 - 1.5e-29 101.9 0.0 3.8e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61235.1 - 6.7e-29 100.3 0.0 1.4e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG61235.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4392 PF14336.6 GBG61235.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) SpoOE-like PF09388.10 GBG61235.1 - 0.16 11.9 0.3 0.73 9.8 0.3 2.1 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Phage_lysozyme PF00959.19 GBG61236.1 - 0.1 13.0 3.2 0.54 10.7 0.0 2.8 3 0 0 3 3 3 0 Phage lysozyme MSP PF01716.18 GBG61238.1 - 1.6e-95 318.9 0.3 2.5e-95 318.3 0.3 1.3 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide Peptidase_S21 PF00716.17 GBG61238.1 - 0.053 13.2 1.7 0.082 12.6 1.7 1.2 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Mago_nashi PF02792.14 GBG61239.1 - 2e-40 138.2 0.0 2.5e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Mago nashi protein Helitron_like_N PF14214.6 GBG61240.1 - 2.7e-21 76.7 0.0 4.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 GBG61240.1 - 9.4e-12 44.8 0.0 3e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 GBG61240.1 - 0.0001 22.1 0.0 0.00031 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AMP_N PF05195.16 GBG61241.1 - 1.5e-27 95.8 0.0 2.1e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Hph PF13694.6 GBG61241.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Sec63/Sec62 complex-interacting family DCP1 PF06058.13 GBG61242.1 - 4.8e-43 145.8 0.4 7.7e-43 145.1 0.4 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Myb_DNA-bind_4 PF13837.6 GBG61242.1 - 2.3e-05 24.7 0.6 5.4e-05 23.5 0.6 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 GBG61242.1 - 0.094 12.9 0.1 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Peptidase_M24 PF00557.24 GBG61243.1 - 7.7e-24 84.5 0.2 1.4e-23 83.7 0.2 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Integrase_H2C2 PF17921.1 GBG61243.1 - 2.8e-21 75.4 0.2 8e-21 73.9 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61243.1 - 2.4e-14 53.6 0.0 5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61243.1 - 0.00024 21.2 0.0 0.00066 19.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger SUR7 PF06687.12 GBG61244.1 - 0.34 10.5 1.2 0.39 10.3 1.2 1.2 1 0 0 1 1 1 0 SUR7/PalI family Menin PF05053.13 GBG61244.1 - 9.9 4.4 11.6 15 3.8 11.6 1.2 1 0 0 1 1 1 0 Menin Retrotrans_gag PF03732.17 GBG61245.1 - 0.011 16.0 0.0 0.22 11.8 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG61246.1 - 1.9e-18 66.6 0.0 4.4e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61246.1 - 2.4e-15 56.4 0.0 5.2e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61246.1 - 3e-11 43.3 0.9 3e-11 43.3 0.9 3.4 4 0 0 4 4 4 1 Integrase zinc binding domain Macoilin PF09726.9 GBG61246.1 - 1.2 7.6 10.4 0.29 9.6 7.2 1.5 1 1 0 1 1 1 0 Macoilin family Abhydrolase_5 PF12695.7 GBG61247.1 - 4.7e-23 81.7 0.0 2.3e-16 60.0 0.0 2.9 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GBG61247.1 - 8.7e-07 29.0 0.0 4.4e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GBG61247.1 - 1.7e-05 24.2 0.1 0.025 13.9 0.0 2.7 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG61247.1 - 0.00053 19.7 0.1 0.043 13.5 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG61247.1 - 0.013 16.1 14.1 0.53 10.8 2.6 2.6 1 1 1 3 3 3 0 Alpha/beta hydrolase family Thioesterase PF00975.20 GBG61247.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.7 GBG61247.1 - 0.18 10.7 0.3 1.4 7.8 0.3 2.1 1 1 0 1 1 1 0 Chlorophyllase enzyme RT_RNaseH_2 PF17919.1 GBG61249.1 - 6.2e-31 106.4 0.0 1.1e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61249.1 - 2.4e-22 79.2 0.0 4.7e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61249.1 - 3e-12 46.5 0.1 5.6e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rdx PF10262.9 GBG61249.1 - 0.07 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Rdx family Acyltransferase PF01553.21 GBG61250.1 - 1.5e-21 76.4 0.0 3.4e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase MatE PF01554.18 GBG61251.1 - 3.4e-43 147.1 25.2 3.4e-23 82.1 10.7 2.3 2 0 0 2 2 2 2 MatE N6_N4_Mtase PF01555.18 GBG61253.1 - 1e-07 31.9 0.0 1e-07 31.9 0.0 1.2 1 1 0 1 1 1 1 DNA methylase Acyl-ACP_TE PF01643.17 GBG61255.1 - 1.7e-70 237.2 0.0 2.3e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase SR-25 PF10500.9 GBG61255.1 - 1.4 8.5 5.8 2.6 7.6 5.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HAUS-augmin3 PF14932.6 GBG61256.1 - 0.003 17.2 6.9 0.004 16.8 6.9 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 AP1AR PF15745.5 GBG61256.1 - 0.0032 17.1 10.6 0.0041 16.8 10.6 1.3 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein SOBP PF15279.6 GBG61256.1 - 0.33 11.5 3.3 0.36 11.4 3.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SmAKAP PF15127.6 GBG61256.1 - 0.47 11.7 7.4 0.98 10.7 7.4 1.5 1 0 0 1 1 1 0 Small membrane A-kinase anchor protein Pro_CA PF00484.19 GBG61256.1 - 0.55 10.5 5.0 0.84 9.9 5.0 1.3 1 0 0 1 1 1 0 Carbonic anhydrase dsRBD2 PF17842.1 GBG61256.1 - 0.67 10.2 6.1 1.2 9.4 6.1 1.4 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 NPAT_C PF15712.5 GBG61256.1 - 2.2 6.8 11.4 2.8 6.5 11.4 1.1 1 0 0 1 1 1 0 NPAT C terminus TMPIT PF07851.13 GBG61256.1 - 3.1 7.0 7.2 4 6.6 7.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein U1snRNP70_N PF12220.8 GBG61256.1 - 3.9 8.2 18.2 0.15 12.7 11.4 2.0 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Sec62 PF03839.16 GBG61256.1 - 9.5 5.7 10.4 12 5.3 10.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 MFS_1 PF07690.16 GBG61257.1 - 2.3e-47 161.6 37.8 2.3e-47 161.6 29.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily KCH PF16944.5 GBG61257.1 - 0.21 11.3 2.5 0.61 9.8 0.0 2.6 3 0 0 3 3 3 0 Fungal potassium channel RVT_1 PF00078.27 GBG61258.1 - 6.2e-32 110.9 0.1 2.1e-31 109.2 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61258.1 - 2.4e-30 104.5 0.0 4.3e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61258.1 - 1.6e-26 92.6 0.0 3.2e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61258.1 - 9.1e-19 67.3 0.1 2.3e-18 66.0 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61258.1 - 6.3e-15 55.4 0.0 1.4e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61258.1 - 0.00014 22.0 0.0 0.00065 19.9 0.0 2.3 1 0 0 1 1 1 1 H2C2 zinc finger NTP_transferase PF00483.23 GBG61259.1 - 1.9e-24 86.6 0.0 2.8e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 GBG61259.1 - 8.8e-06 25.3 13.1 2.3e-05 23.9 0.6 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GBG61259.1 - 0.00086 19.7 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 GBG61259.1 - 0.032 14.2 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DUF4954 PF16314.5 GBG61259.1 - 0.044 11.9 0.3 0.068 11.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) DUF4376 PF14301.6 GBG61262.1 - 0.012 15.9 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) RVT_1 PF00078.27 GBG61263.1 - 1.4e-28 99.9 0.1 2.3e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61263.1 - 3.1e-24 84.9 0.0 6.7e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61263.1 - 4.7e-23 81.5 0.0 1e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG61263.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain CENP-K PF11802.8 GBG61263.1 - 1.3 8.5 4.7 3 7.3 4.7 1.5 1 0 0 1 1 1 0 Centromere-associated protein K RVT_1 PF00078.27 GBG61264.1 - 1e-25 90.6 0.1 1.9e-25 89.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61264.1 - 5.3e-23 81.3 0.0 1e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61264.1 - 4.7e-22 77.9 0.0 1.3e-21 76.5 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61264.1 - 9.8e-17 60.8 1.4 2.6e-16 59.5 1.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG61264.1 - 3e-09 37.1 0.0 8.7e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61264.1 - 0.052 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Pkinase PF00069.25 GBG61265.1 - 1.4e-47 162.3 0.0 1.7e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61265.1 - 1.9e-45 155.2 0.0 2.4e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG61265.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GBG61265.1 - 0.022 13.7 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 GBG61265.1 - 0.048 13.6 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG61265.1 - 0.14 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 GBG61268.1 - 5.6e-47 160.3 0.0 6.5e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61268.1 - 1.6e-45 155.5 0.0 2.1e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG61268.1 - 0.00075 18.9 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GBG61268.1 - 0.0048 15.9 0.0 0.1 11.5 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GBG61268.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG61268.1 - 0.048 12.4 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Suf PF05843.14 GBG61269.1 - 3e-71 240.8 7.1 9.5e-69 232.6 0.0 4.6 5 1 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 GBG61269.1 - 6.6e-10 39.0 11.6 0.00025 21.6 0.5 5.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 GBG61269.1 - 4.2e-06 27.2 3.5 0.00014 22.3 0.7 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 GBG61269.1 - 8.7e-06 25.1 0.6 0.016 14.4 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG61269.1 - 0.00067 19.9 0.1 4.2 8.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GBG61269.1 - 0.0078 16.8 1.2 1.8 9.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG61269.1 - 0.0079 16.2 0.2 0.25 11.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG61269.1 - 0.2 12.3 11.8 3.6 8.3 2.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GBG61269.1 - 0.91 9.5 3.2 23 5.0 0.4 3.8 2 2 1 3 3 3 0 Mad3/BUB1 homology region 1 Pkinase_Tyr PF07714.17 GBG61270.1 - 1.9e-43 148.6 0.0 3.1e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG61270.1 - 4.2e-42 144.3 0.0 5.8e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Myb_DNA-bind_4 PF13837.6 GBG61271.1 - 6.7e-07 29.6 3.6 1.2e-06 28.8 3.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG61271.1 - 0.00096 19.2 3.0 0.0017 18.4 2.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG61271.1 - 0.0033 17.6 1.5 0.0059 16.8 1.5 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG61271.1 - 0.012 15.9 1.4 0.026 14.8 1.4 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG61271.1 - 0.048 13.9 0.5 0.089 13.0 0.5 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-CCHC PF00098.23 GBG61272.1 - 0.00015 21.7 0.7 0.0003 20.7 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG61272.1 - 0.02 14.7 0.9 0.038 13.8 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF5576 PF17739.1 GBG61272.1 - 0.037 14.1 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5576) CDC45 PF02724.14 GBG61272.1 - 0.11 10.8 8.9 0.16 10.3 7.1 1.8 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 GBG61272.1 - 3.6 5.7 11.9 5.6 5.0 11.9 1.2 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG61273.1 - 4.3e-29 101.6 0.0 6.4e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG61275.1 - 7.6e-46 156.6 0.0 9.9e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61275.1 - 3e-45 154.5 0.0 4.3e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG61275.1 - 0.0006 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family U83 PF17465.2 GBG61275.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Chemokine-like protein, HHV-6 U83 gene product Pkinase_fungal PF17667.1 GBG61275.1 - 0.088 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Prismane PF03063.20 GBG61276.1 - 1.3e-102 344.1 1.8 1.4e-59 202.1 0.6 2.0 1 1 1 2 2 2 2 Prismane/CO dehydrogenase family RT_RNaseH_2 PF17919.1 GBG61277.1 - 8.5e-25 86.7 0.0 1.8e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61277.1 - 5.7e-21 74.8 0.0 2.7e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61277.1 - 9.2e-13 48.4 0.0 1.6e-11 44.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG61277.1 - 0.0022 17.7 0.0 0.0067 16.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG61277.1 - 0.012 16.2 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61277.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG61277.1 - 0.13 12.6 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG61278.1 - 1.1e-05 25.3 0.8 3.2e-05 23.8 0.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG61278.1 - 1.2 8.9 5.9 0.24 11.1 1.5 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_1 PF00078.27 GBG61279.1 - 1.8e-27 96.3 0.1 5e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61279.1 - 7.7e-25 86.8 0.0 2.1e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61279.1 - 3.9e-24 84.9 0.0 1e-23 83.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61279.1 - 9.2e-20 70.5 0.2 2e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG61279.1 - 5.4e-08 33.4 0.0 1.3e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG61279.1 - 1.7e-07 31.1 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG61279.1 - 2e-05 25.0 0.0 6e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG61279.1 - 0.0022 18.2 0.1 0.0022 18.2 0.1 3.5 5 0 0 5 5 5 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG61279.1 - 0.017 15.3 0.0 0.05 13.8 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG61279.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TAF4 PF05236.14 GBG61279.1 - 0.066 13.0 6.7 0.14 11.9 6.7 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family P4Ha_N PF08336.11 GBG61279.1 - 0.6 10.1 5.7 1.5 8.8 0.1 3.0 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region IBR PF01485.21 GBG61279.1 - 2.9 8.2 7.7 16 5.8 0.4 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DUF4187 PF13821.6 GBG61279.1 - 4.3 7.2 9.1 0.27 11.1 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Casc1_N PF15927.5 GBG61279.1 - 6.1 6.5 13.7 19 4.9 13.7 1.8 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus MatE PF01554.18 GBG61282.1 - 3.9e-48 163.2 26.2 3.4e-25 88.6 14.4 2.6 2 1 0 2 2 2 2 MatE RT_RNaseH PF17917.1 GBG61283.1 - 1.6e-22 79.8 0.0 3.5e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61283.1 - 5.5e-21 74.5 0.0 1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61283.1 - 2.8e-14 53.0 0.1 8.8e-14 51.4 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61283.1 - 1.7e-07 31.4 0.0 5.8e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61283.1 - 0.0058 16.8 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Macoilin PF09726.9 GBG61284.1 - 5.4 5.5 8.6 6.9 5.1 8.6 1.0 1 0 0 1 1 1 0 Macoilin family MatE PF01554.18 GBG61285.1 - 3.9e-50 169.6 22.7 7.4e-27 94.0 12.7 2.4 2 0 0 2 2 2 2 MatE BUD22 PF09073.10 GBG61286.1 - 2.6 7.3 33.9 2.8 7.2 33.9 1.0 1 0 0 1 1 1 0 BUD22 SCAB_CC PF16712.5 GBG61287.1 - 2.6e-28 98.9 15.3 5.7e-28 97.8 15.3 1.5 1 0 0 1 1 1 1 Coiled-coil regions of plant-specific actin-binding protein SCAB-PH PF17684.1 GBG61287.1 - 2.7e-27 95.2 0.0 6.5e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 PH domain of plant-specific actin-binding protein SCAB-Ig PF16709.5 GBG61287.1 - 2.6e-20 72.3 0.0 5.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Ig domain of plant-specific actin-binding protein SCAB-ABD PF16711.5 GBG61287.1 - 0.0017 18.2 0.1 0.0017 18.2 0.1 2.3 3 0 0 3 3 3 1 Actin-binding domain of plant-specific actin-binding protein DUF883 PF05957.13 GBG61287.1 - 0.053 14.1 2.5 0.32 11.6 2.5 2.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) CDC45 PF02724.14 GBG61287.1 - 0.33 9.2 11.3 0.7 8.1 11.3 1.5 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 GBG61287.1 - 5.1 5.1 6.2 11 4.0 6.2 1.5 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Na_trans_assoc PF06512.13 GBG61287.1 - 9.9 6.4 18.4 0.81 9.9 13.2 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated gag-asp_proteas PF13975.6 GBG61288.1 - 5.2e-07 30.1 0.2 1.8e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61288.1 - 4.3e-05 24.1 0.4 0.00013 22.5 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG61288.1 - 0.0027 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG61288.1 - 0.013 15.2 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG61288.1 - 0.014 15.0 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like cNMP_binding PF00027.29 GBG61288.1 - 0.06 13.4 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain Pro_isomerase PF00160.21 GBG61289.1 - 1.3e-16 61.3 0.0 2.4e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GCP_N_terminal PF17681.1 GBG61290.1 - 4.3e-12 46.3 0.0 7.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal IFT81_CH PF18383.1 GBG61291.1 - 0.054 13.7 0.1 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 Intraflagellar transport 81 calponin homology domain RVT_1 PF00078.27 GBG61292.1 - 4.8e-32 111.3 0.0 8.3e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PUD1_2 PF18457.1 GBG61293.1 - 2.3e-28 99.3 0.0 2.5e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Up-Regulated in long-lived daf-2 RVT_1 PF00078.27 GBG61294.1 - 4.7e-35 121.1 0.1 8e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61294.1 - 3.5e-29 101.2 0.0 9.8e-29 99.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61294.1 - 4.4e-29 100.5 0.0 3.9e-28 97.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG61294.1 - 5.4e-05 23.0 0.0 0.00014 21.7 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61294.1 - 0.0005 20.7 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Ssu72 PF04722.13 GBG61294.1 - 0.1 12.2 0.1 0.42 10.1 0.0 2.0 2 0 0 2 2 2 0 Ssu72-like protein gag-asp_proteas PF13975.6 GBG61294.1 - 0.14 12.7 0.0 0.42 11.2 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61294.1 - 0.16 11.8 0.0 1 9.2 0.0 2.2 2 1 0 2 2 2 0 Aspartyl protease NOA36 PF06524.12 GBG61295.1 - 0.37 10.1 11.3 0.45 9.8 11.3 1.1 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 GBG61295.1 - 0.5 9.7 14.3 0.61 9.5 14.3 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG61295.1 - 0.67 9.2 10.8 0.72 9.1 10.8 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG61295.1 - 0.77 8.0 9.9 0.82 7.9 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG61295.1 - 0.82 7.8 17.0 0.97 7.6 17.0 1.0 1 0 0 1 1 1 0 Nop14-like family Prothymosin PF03247.14 GBG61295.1 - 2.2 8.8 34.1 3.9 8.0 34.1 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Mpp10 PF04006.12 GBG61295.1 - 5.1 5.4 17.8 6.1 5.2 17.8 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG61296.1 - 0.5 9.7 47.3 0.64 9.4 47.3 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG61297.1 - 0.22 9.7 12.4 0.29 9.3 12.4 1.2 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 GBG61297.1 - 1 8.9 14.6 1.3 8.6 14.6 1.1 1 0 0 1 1 1 0 PPP4R2 RPN2_C PF18004.1 GBG61297.1 - 1.1 9.1 14.6 1.7 8.5 14.6 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RXT2_N PF08595.11 GBG61297.1 - 5.5 7.0 11.3 8.5 6.4 11.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Serglycin PF04360.12 GBG61298.1 - 1.9 8.4 5.3 3.3 7.6 5.3 1.3 1 0 0 1 1 1 0 Serglycin DUF659 PF04937.15 GBG61299.1 - 0.0002 21.2 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG61300.1 - 4.2e-29 101.7 0.1 9.5e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61300.1 - 8.5e-25 86.7 0.0 2.2e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61300.1 - 3.2e-22 78.8 0.0 8e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG61300.1 - 1.9e-06 28.3 0.1 1.3e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG61300.1 - 9.2e-06 25.5 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61300.1 - 1.5e-05 25.5 0.0 5.4e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG61300.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease SLT_L PF14718.6 GBG61300.1 - 1.3 9.2 9.9 2.1 8.5 8.3 2.2 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain Retrotrans_gag PF03732.17 GBG61301.1 - 0.0014 18.9 11.8 0.0039 17.4 0.0 4.2 4 1 0 4 4 4 1 Retrotransposon gag protein SlyX PF04102.12 GBG61301.1 - 0.006 17.2 0.8 0.006 17.2 0.8 3.5 3 1 0 3 3 3 1 SlyX HIP1_clath_bdg PF16515.5 GBG61301.1 - 0.012 16.2 7.0 0.012 16.2 7.0 3.4 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BLOC1_2 PF10046.9 GBG61301.1 - 0.025 14.9 2.6 0.025 14.9 2.6 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GBG61301.1 - 0.038 14.5 3.3 0.96 10.0 0.1 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Gp58 PF07902.11 GBG61301.1 - 0.061 11.6 1.2 0.094 11.0 1.2 1.2 1 0 0 1 1 1 0 gp58-like protein DUF1664 PF07889.12 GBG61301.1 - 0.29 11.2 3.7 5.7 7.0 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Borrelia_P83 PF05262.11 GBG61301.1 - 0.4 9.1 9.6 0.54 8.7 9.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein FliD_N PF02465.18 GBG61301.1 - 1.2 9.9 7.0 1.1 10.0 0.1 3.2 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF4972 PF16342.5 GBG61301.1 - 1.7 8.3 4.7 7.8 6.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4972) SPACA9 PF15120.6 GBG61301.1 - 1.8 8.3 7.1 0.3 10.8 0.4 2.9 3 2 1 4 4 4 0 Sperm acrosome-associated protein 9 LMBR1 PF04791.16 GBG61301.1 - 2.5 6.9 4.2 3.5 6.4 4.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 GBG61301.1 - 2.8 7.8 18.1 0.13 12.1 3.3 3.4 3 1 0 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 GBG61301.1 - 7 5.9 15.4 6.1 6.1 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG61302.1 - 4.8e-29 101.5 0.3 1e-28 100.4 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61302.1 - 1.2e-23 83.1 0.0 2.1e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61302.1 - 9.2e-22 77.3 0.0 1.8e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61302.1 - 4e-19 68.5 0.1 9.8e-19 67.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG61302.1 - 0.0033 17.6 0.0 0.0078 16.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger PARP_reg PF02877.14 GBG61303.1 - 0.023 14.8 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain PARP PF00644.20 GBG61303.1 - 0.23 11.0 0.0 2.5 7.7 0.0 2.0 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase catalytic domain RT_RNaseH PF17917.1 GBG61304.1 - 2.7e-16 59.7 0.0 4.5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61304.1 - 6.6e-14 51.8 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61304.1 - 0.00049 19.7 0.0 0.00084 18.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG61306.1 - 2.8e-26 92.1 0.0 5.1e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61306.1 - 1.4e-17 64.0 0.0 1.9e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein FXR_C1 PF16096.5 GBG61306.1 - 0.22 11.7 5.0 0.28 11.4 4.2 1.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DDE_Tnp_1 PF01609.21 GBG61306.1 - 1.1 8.9 7.8 2.1 7.9 3.3 2.7 2 1 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG61307.1 - 6.9e-06 26.4 1.8 1.2e-05 25.6 1.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG61307.1 - 0.0036 17.4 1.2 0.0059 16.6 1.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TFIIA PF03153.13 GBG61307.1 - 0.018 15.1 7.3 0.024 14.6 7.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GCIP PF13324.6 GBG61307.1 - 0.26 10.9 5.3 0.44 10.1 5.3 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC45 PF02724.14 GBG61307.1 - 0.3 9.3 8.1 0.49 8.6 8.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 GBG61307.1 - 0.67 9.8 10.3 1.4 8.8 10.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 GBG61307.1 - 1.4 8.5 6.0 3.7 7.2 6.0 1.6 1 0 0 1 1 1 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 GBG61307.1 - 3 8.0 22.0 0.48 10.6 18.0 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 GBG61307.1 - 5.9 6.1 25.0 12 5.1 25.0 1.4 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 GBG61307.1 - 8.7 5.8 13.6 1.7 8.2 10.2 1.4 2 0 0 2 2 2 0 PPP4R2 TIM PF00121.18 GBG61308.1 - 1.7e-90 302.7 0.1 1.9e-90 302.5 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 GBG61308.1 - 0.092 12.2 0.0 0.28 10.6 0.0 1.8 1 1 1 2 2 2 0 CutC family DDE_Tnp_4 PF13359.6 GBG61309.1 - 5e-27 94.5 0.1 2e-26 92.6 0.0 1.9 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61309.1 - 1.4e-13 50.9 0.0 2.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61309.1 - 0.00027 20.7 0.1 0.0026 17.4 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG61309.1 - 0.029 14.7 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain LRR_4 PF12799.7 GBG61310.1 - 7.5e-11 42.1 5.4 0.22 12.0 0.9 8.7 5 4 5 10 10 10 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG61310.1 - 7.1e-09 35.0 20.6 5.5 7.3 0.0 12.8 15 0 0 15 15 15 2 Leucine Rich repeat F-box-like PF12937.7 GBG61310.1 - 3.4e-08 33.3 0.2 1.6e-06 27.9 0.1 3.0 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.6 GBG61310.1 - 0.011 15.4 3.2 31 4.4 0.2 5.8 6 2 2 8 8 8 0 Leucine rich repeat LRR_1 PF00560.33 GBG61310.1 - 0.032 14.8 17.6 90 4.2 0.1 9.7 11 2 1 12 12 12 0 Leucine Rich Repeat F-box_5 PF18511.1 GBG61310.1 - 0.095 12.3 0.1 0.27 10.8 0.1 1.8 1 0 0 1 1 1 0 F-box F-box PF00646.33 GBG61310.1 - 0.095 12.6 0.2 0.095 12.6 0.2 3.8 4 0 0 4 4 4 0 F-box domain Abhydrolase_5 PF12695.7 GBG61312.1 - 6e-21 74.9 0.1 3.3e-20 72.5 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 GBG61312.1 - 8.4e-05 22.8 0.1 0.00012 22.2 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 GBG61312.1 - 0.00021 21.0 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GBG61312.1 - 0.00094 19.0 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GBG61312.1 - 0.0052 16.1 0.1 0.012 14.8 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 GBG61312.1 - 0.017 14.1 0.3 0.12 11.4 0.3 2.0 1 1 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 GBG61312.1 - 0.022 13.7 0.1 0.088 11.7 0.1 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 GBG61312.1 - 0.11 13.0 1.9 0.18 12.4 1.6 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-CCHC PF00098.23 GBG61313.1 - 2.6e-07 30.4 3.0 6.2e-07 29.2 3.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG61313.1 - 0.013 15.3 2.2 0.023 14.5 2.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Serpin PF00079.20 GBG61314.1 - 1.4e-90 304.3 0.0 1.6e-90 304.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Angiomotin_C PF12240.8 GBG61315.1 - 0.002 17.7 0.1 0.002 17.7 0.1 2.0 2 0 0 2 2 2 1 Angiomotin C terminal Retrotrans_gag PF03732.17 GBG61315.1 - 0.026 14.8 0.0 0.072 13.4 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Serpin PF00079.20 GBG61317.1 - 8e-47 160.3 0.0 9.9e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 GBG61320.1 - 1.3e-90 304.5 0.0 1.5e-90 304.2 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pyridoxal_deC PF00282.19 GBG61321.1 - 6.7e-96 321.2 0.0 8.7e-96 320.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GBG61321.1 - 0.0002 20.4 0.0 0.0078 15.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Dimer_Tnp_hAT PF05699.14 GBG61322.1 - 0.0008 19.1 0.2 0.0015 18.3 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG61323.1 - 1.1e-30 105.6 0.0 7.2e-15 54.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61323.1 - 1.7e-30 105.4 0.0 3.4e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61323.1 - 3.2e-13 49.6 0.1 1.1e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG61323.1 - 4.4e-12 46.2 0.0 1.6e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG61323.1 - 2.3e-06 27.3 0.0 4.4e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG61323.1 - 0.002 18.3 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger PGM_PMM_II PF02879.16 GBG61325.1 - 2.7e-12 47.2 0.0 7.6e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.16 GBG61325.1 - 2.2e-10 40.4 0.1 6.6e-09 35.6 0.0 2.2 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GBG61325.1 - 4.2e-09 36.6 0.0 2.3e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 GBG61325.1 - 4.6e-07 29.9 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF3631 PF12307.8 GBG61325.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) Mpp10 PF04006.12 GBG61326.1 - 0.59 8.5 28.9 0.7 8.3 28.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG61326.1 - 0.96 7.6 42.2 1.1 7.4 42.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG61326.1 - 5 5.3 35.8 6 5.0 35.8 1.1 1 0 0 1 1 1 0 CDC45-like protein UBA PF00627.31 GBG61327.1 - 1.2e-26 92.2 6.4 3.2e-15 55.7 0.9 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 GBG61327.1 - 6.3e-23 80.3 11.0 1.1e-22 79.5 11.0 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 GBG61327.1 - 8.5e-21 73.5 1.7 1.3e-20 72.9 1.7 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GBG61327.1 - 1.4e-05 24.8 2.0 2.3e-05 24.1 2.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 GBG61327.1 - 0.0024 17.7 0.0 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain CUE PF02845.16 GBG61327.1 - 0.017 14.8 0.0 6.1 6.6 0.0 2.6 2 0 0 2 2 2 0 CUE domain Rad60-SLD_2 PF13881.6 GBG61327.1 - 0.094 12.8 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ELYS PF13934.6 GBG61328.1 - 6.3e-31 108.1 0.0 1.2e-30 107.2 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore complex assembly zf-C3HC4_3 PF13920.6 GBG61328.1 - 5.1e-06 26.2 9.5 1.4e-05 24.9 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG61328.1 - 0.026 14.5 9.5 0.06 13.3 9.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain SpoU_methylase PF00588.19 GBG61329.1 - 4.2e-26 91.8 0.0 7.7e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GBG61329.1 - 9.9e-13 48.2 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF296 PF03479.15 GBG61329.1 - 0.49 10.8 2.2 0.67 10.4 0.6 2.0 2 0 0 2 2 2 0 Plants and Prokaryotes Conserved (PCC) domain Integrase_H2C2 PF17921.1 GBG61330.1 - 1e-15 57.5 0.0 2.2e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61330.1 - 1.7e-12 47.5 0.0 3.7e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG61330.1 - 9e-09 35.8 0.0 2.1e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61330.1 - 3.5e-07 30.8 0.0 7.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG61330.1 - 2.3e-05 24.2 0.1 5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG61330.1 - 0.036 14.3 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 GBG61330.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG61330.1 - 0.18 12.0 2.1 0.53 10.5 2.1 1.9 1 0 0 1 1 1 0 Zinc knuckle PTPRCAP PF15713.5 GBG61330.1 - 2.1 8.6 10.0 13 6.0 10.0 2.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Sin3_corepress PF08295.12 GBG61331.1 - 3.1e-34 116.9 1.1 7.3e-34 115.8 1.1 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 GBG61331.1 - 1.9e-32 111.2 5.1 1.7e-15 56.8 0.2 4.0 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3a_C PF16879.5 GBG61331.1 - 6.3e-26 91.8 0.0 3.9e-24 85.9 0.0 3.1 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein SUIM_assoc PF16619.5 GBG61331.1 - 0.0014 18.6 6.9 0.032 14.3 3.4 4.1 4 1 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GBG61331.1 - 3.1 7.3 15.8 0.48 10.0 9.2 2.2 2 0 0 2 2 2 0 Spt20 family RRM_1 PF00076.22 GBG61332.1 - 5.3e-37 125.5 0.0 1.8e-19 69.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG61332.1 - 1.2e-14 54.2 0.1 1.6e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GBG61332.1 - 0.00039 20.4 0.1 0.75 9.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 GBG61332.1 - 0.0015 18.5 0.0 0.95 9.5 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 GBG61332.1 - 0.023 14.4 0.1 9.2 6.0 0.0 2.9 2 0 0 2 2 2 0 Ribonuclease B OB domain RL PF17797.1 GBG61332.1 - 0.097 12.6 0.1 0.23 11.4 0.1 1.6 2 0 0 2 2 2 0 RL domain PHM7_cyt PF14703.6 GBG61332.1 - 0.2 11.8 0.0 7.7 6.7 0.0 2.4 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Spem1 PF15670.5 GBG61334.1 - 0.1 12.2 0.1 0.11 12.1 0.1 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 PRKCSH-like PF12999.7 GBG61335.1 - 8.8e-18 64.7 4.7 8.8e-18 64.7 4.7 3.9 4 1 1 5 5 5 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 GBG61335.1 - 9.8e-16 57.8 0.2 4.5e-15 55.6 0.1 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 GBG61335.1 - 0.00058 20.8 1.8 0.00058 20.8 1.8 3.6 4 0 0 4 4 4 1 Glucosidase II beta subunit-like protein REV PF00424.18 GBG61335.1 - 1.4 9.0 4.9 0.82 9.7 0.9 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) PRKCSH-like PF12999.7 GBG61336.1 - 8.9e-18 64.7 4.8 8.9e-18 64.7 4.8 4.3 4 1 1 5 5 5 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 GBG61336.1 - 9.1e-16 57.9 0.2 4.3e-15 55.7 0.1 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 GBG61336.1 - 0.00056 20.9 1.8 0.00056 20.9 1.8 3.6 4 0 0 4 4 4 1 Glucosidase II beta subunit-like protein REV PF00424.18 GBG61336.1 - 1.3 9.1 4.8 0.79 9.8 0.9 2.5 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) RVP_2 PF08284.11 GBG61337.1 - 2.8e-05 23.9 0.0 6.7e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61337.1 - 4.7e-05 24.0 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG61337.1 - 0.00019 21.7 0.6 0.0097 16.2 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG61337.1 - 0.0012 19.4 0.3 0.0039 17.7 0.1 2.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG61337.1 - 0.02 14.7 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG61337.1 - 0.13 12.1 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease SufE PF02657.15 GBG61338.1 - 2.1e-34 118.0 0.0 5.8e-34 116.6 0.0 1.8 2 0 0 2 2 2 1 Fe-S metabolism associated domain NadA PF02445.16 GBG61338.1 - 8e-32 110.6 0.9 1.3e-30 106.6 0.3 2.1 2 0 0 2 2 2 2 Quinolinate synthetase A protein TadF PF16964.5 GBG61339.1 - 2.8 7.7 6.1 0.58 9.9 2.9 1.6 2 0 0 2 2 2 0 Putative tight adherence pilin protein F RINT1_TIP1 PF04437.13 GBG61340.1 - 3.2e-47 161.6 0.0 4.7e-25 88.4 0.0 2.8 2 1 0 2 2 2 2 RINT-1 / TIP-1 family CAP_N PF01213.19 GBG61340.1 - 5 6.5 5.6 2.6 7.5 2.0 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal vATP-synt_AC39 PF01992.16 GBG61341.1 - 8.2e-111 370.7 0.9 9.3e-111 370.6 0.9 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SDA1 PF05285.12 GBG61343.1 - 7 6.0 15.9 7 6.0 15.9 1.0 1 0 0 1 1 1 0 SDA1 C2 PF00168.30 GBG61344.1 - 2.7e-36 124.0 0.0 1.4e-16 60.7 0.0 3.3 2 1 1 3 3 3 3 C2 domain SMP_LBD PF17047.5 GBG61344.1 - 5.6e-19 68.3 0.3 8.2e-19 67.8 0.3 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 GBG61345.1 - 3.3e-35 120.5 0.0 6.5e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 GBG61345.1 - 5.3e-19 68.4 0.3 7.6e-19 67.9 0.3 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Bestrophin PF01062.21 GBG61348.1 - 8e-20 71.4 1.8 1.1e-19 70.9 1.8 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Myb_DNA-bind_4 PF13837.6 GBG61349.1 - 5.2e-10 39.6 9.0 5.2e-10 39.6 9.0 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG61351.1 - 3.4e-23 81.6 0.1 7.6e-23 80.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61351.1 - 9.1e-13 48.2 0.1 1.4e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61351.1 - 6.8e-11 42.4 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG61352.1 - 7.1e-29 100.5 0.0 1.1e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61352.1 - 2.1e-14 53.6 0.0 3.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61352.1 - 0.0039 16.8 0.1 0.74 9.4 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG61352.1 - 0.021 15.2 0.4 0.073 13.5 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain GatB_N PF02934.15 GBG61353.1 - 5.3e-112 373.7 0.0 6.8e-112 373.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 GBG61353.1 - 5.6e-50 169.1 0.2 9.2e-50 168.4 0.2 1.4 1 0 0 1 1 1 1 GatB domain DUF2052 PF09747.9 GBG61354.1 - 0.3 11.2 20.2 1.1 9.3 1.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Usp PF00582.26 GBG61354.1 - 6.7 7.2 9.6 5.1 7.6 2.1 2.3 2 0 0 2 2 2 0 Universal stress protein family Eapp_C PF10238.9 GBG61354.1 - 7.1 6.7 11.5 6.6 6.8 5.1 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein Bestrophin PF01062.21 GBG61357.1 - 1e-19 71.0 0.5 1.6e-19 70.4 0.5 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Stealth_CR3 PF17102.5 GBG61357.1 - 3.2 7.7 6.5 1.6 8.7 1.0 3.2 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 Sec34 PF04136.15 GBG61358.1 - 3e-43 147.2 0.6 3e-43 147.2 0.6 2.1 3 0 0 3 3 3 1 Sec34-like family DHHA1 PF02272.19 GBG61358.1 - 0.0058 17.1 0.0 0.0058 17.1 0.0 4.0 4 1 1 5 5 5 1 DHHA1 domain Secretin_N PF03958.17 GBG61358.1 - 0.2 12.1 0.1 0.2 12.1 0.1 3.2 3 1 0 3 3 3 0 Bacterial type II/III secretion system short domain E1-E2_ATPase PF00122.20 GBG61359.1 - 5.3e-43 146.6 0.1 1.4e-42 145.2 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GBG61359.1 - 6.4e-32 111.5 2.9 1.1e-31 110.7 2.9 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GBG61359.1 - 5.4e-11 42.8 1.2 7.4e-11 42.3 0.1 1.9 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GBG61359.1 - 0.004 16.9 0.5 0.04 13.7 0.6 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase UreF PF01730.16 GBG61359.1 - 0.11 13.0 3.7 5.8 7.5 0.1 3.5 3 0 0 3 3 3 0 UreF MMR_HSR1 PF01926.23 GBG61361.1 - 1e-24 86.8 0.0 2.6e-24 85.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG61361.1 - 4.2e-16 58.8 0.0 6.9e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B KH_2 PF07650.17 GBG61361.1 - 1.2e-14 53.9 0.4 2.7e-14 52.7 0.4 1.7 1 0 0 1 1 1 1 KH domain RsgA_GTPase PF03193.16 GBG61361.1 - 5.3e-08 32.9 0.0 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 GBG61361.1 - 7.5e-07 29.3 2.1 0.0013 18.8 0.0 2.6 2 1 1 3 3 2 2 Dynamin family AIG1 PF04548.16 GBG61361.1 - 7.1e-05 22.2 0.0 0.00017 21.0 0.0 1.6 2 0 0 2 2 2 1 AIG1 family PduV-EutP PF10662.9 GBG61361.1 - 0.00036 20.3 0.0 0.00098 18.9 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 GBG61361.1 - 0.00092 18.8 0.1 0.15 11.6 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 GBG61361.1 - 0.0043 16.7 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG61361.1 - 0.0048 17.1 0.0 0.021 15.1 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 GBG61361.1 - 0.0099 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 GBG61361.1 - 0.023 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 GBG61361.1 - 0.038 13.8 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 GBG61361.1 - 0.039 14.5 0.8 0.35 11.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 GBG61361.1 - 0.064 13.2 0.2 12 5.8 0.0 2.3 2 0 0 2 2 2 0 NTPase Arf PF00025.21 GBG61361.1 - 0.1 12.0 0.0 0.27 10.7 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_29 PF13555.6 GBG61361.1 - 0.34 10.7 1.8 0.55 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain HisKA PF00512.25 GBG61362.1 - 2.2e-16 59.6 1.7 2.2e-16 59.6 1.7 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF659 PF04937.15 GBG61362.1 - 3.8e-16 59.3 0.0 6.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61362.1 - 0.00047 19.9 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HATPase_c PF02518.26 GBG61362.1 - 0.0017 18.8 0.0 0.0035 17.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 GBG61362.1 - 0.0034 18.0 0.0 0.013 16.1 0.0 2.1 1 0 0 1 1 1 1 GAF domain Lin-8 PF03353.15 GBG61362.1 - 1.8 8.1 16.0 3.1 7.3 16.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4614 PF15391.6 GBG61362.1 - 3.4 7.6 8.5 10 6.0 8.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Response_reg PF00072.24 GBG61364.1 - 6.6e-22 77.8 0.0 8.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Nop14 PF04147.12 GBG61365.1 - 0.39 8.9 11.1 0.5 8.5 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG61365.1 - 0.87 7.8 8.9 1.2 7.4 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG61365.1 - 2.3 7.5 11.4 3 7.2 11.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG61365.1 - 4.4 6.5 15.3 6.2 6.1 15.3 1.1 1 0 0 1 1 1 0 BUD22 Mei4 PF13971.6 GBG61366.1 - 0.072 12.6 5.5 0.08 12.4 5.5 1.2 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Myc_N PF01056.18 GBG61366.1 - 0.25 11.2 16.3 0.29 11.0 16.3 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Nucleo_P87 PF07267.11 GBG61366.1 - 1.6 7.5 11.6 2.1 7.1 11.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 UPF0524 PF15823.5 GBG61366.1 - 1.9 7.8 6.6 2.4 7.5 6.6 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 DDHD PF02862.17 GBG61366.1 - 2.2 8.4 6.9 2.9 8.0 6.9 1.2 1 0 0 1 1 1 0 DDHD domain BUD22 PF09073.10 GBG61366.1 - 2.4 7.4 25.7 2.8 7.2 25.7 1.0 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GBG61366.1 - 2.8 7.6 24.8 3.4 7.3 24.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GAGA_bind PF06217.12 GBG61366.1 - 3.6 7.8 9.7 4 7.6 9.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CENP-B_dimeris PF09026.10 GBG61366.1 - 4.5 7.7 14.8 11 6.5 14.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TPR_2 PF07719.17 GBG61367.1 - 3.6e-08 32.9 12.6 0.081 13.1 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG61367.1 - 6.5e-08 33.1 10.8 0.00069 20.2 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG61367.1 - 3.3e-07 29.8 1.9 1.3 9.2 0.1 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG61367.1 - 2e-06 28.2 11.3 0.00026 21.4 0.5 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG61367.1 - 5e-05 23.8 12.3 0.57 11.1 0.5 6.3 4 1 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG61367.1 - 0.00088 19.5 7.6 0.93 9.8 0.0 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 GBG61367.1 - 0.0012 18.9 2.4 5.6 7.1 0.0 4.2 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 GBG61367.1 - 0.0058 15.9 1.0 0.81 8.8 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 GBG61367.1 - 0.0062 17.0 0.3 0.0062 17.0 0.3 2.7 4 0 0 4 4 3 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 GBG61367.1 - 0.0067 16.7 7.8 1.1 9.6 0.3 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG61367.1 - 0.013 15.3 10.8 0.066 13.1 0.3 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG61367.1 - 0.26 11.5 1.2 7.7 6.8 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GBG61367.1 - 0.34 10.6 5.4 14 5.4 0.1 4.4 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 GBG61368.1 - 2.2e-08 33.6 12.6 0.075 13.2 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG61368.1 - 4.4e-08 33.6 10.8 0.00063 20.3 0.0 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG61368.1 - 2.2e-07 30.4 1.9 1.2 9.3 0.1 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG61368.1 - 1.8e-06 28.3 11.7 0.00024 21.6 0.5 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG61368.1 - 2.9e-05 24.5 12.3 0.52 11.3 0.5 6.4 4 1 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG61368.1 - 0.00065 19.9 7.7 0.86 9.9 0.0 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 GBG61368.1 - 0.00087 19.3 2.4 5.2 7.2 0.0 4.2 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 GBG61368.1 - 0.0046 16.2 0.9 0.74 9.0 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG61368.1 - 0.0049 17.1 7.8 1 9.7 0.3 4.3 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG61368.1 - 0.0056 16.5 10.2 0.061 13.2 0.3 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 GBG61368.1 - 0.0057 17.1 0.3 0.0057 17.1 0.3 2.8 4 0 0 4 4 3 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 GBG61368.1 - 0.2 11.8 1.2 7 6.9 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GBG61368.1 - 0.23 11.2 5.4 13 5.6 0.1 4.5 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 GBG61369.1 - 1.8e-06 27.6 2.7 0.084 13.0 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG61369.1 - 7.8e-06 26.3 0.7 7.7e-05 23.1 0.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG61369.1 - 2e-05 25.1 4.9 0.00019 22.0 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG61369.1 - 2.7e-05 23.9 1.0 0.42 10.8 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG61369.1 - 3.7e-05 24.2 2.5 0.14 13.0 0.5 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 GBG61369.1 - 0.0004 20.9 0.2 0.0013 19.2 0.1 1.9 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_1 PF00515.28 GBG61369.1 - 0.00059 19.5 2.9 0.021 14.6 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG61369.1 - 0.0006 20.1 3.0 0.31 11.3 0.2 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 GBG61369.1 - 0.0059 16.7 0.2 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 GBG61369.1 - 0.025 15.2 1.5 20 6.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG61369.1 - 0.055 13.6 0.4 2.1 8.5 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG61369.1 - 0.34 11.2 1.5 7.1 6.9 0.4 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SRAP PF02586.14 GBG61370.1 - 5.7e-58 196.0 0.2 1.2e-57 195.0 0.1 1.6 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) RVT_1 PF00078.27 GBG61371.1 - 2e-28 99.4 0.1 3.3e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61371.1 - 3.1e-28 97.7 0.0 4.7e-13 49.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61371.1 - 1.3e-27 96.1 0.0 3.1e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61371.1 - 1.9e-14 53.5 0.1 4e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61371.1 - 1.8e-09 37.8 1.2 2.7e-08 34.0 0.0 3.3 3 0 0 3 3 3 1 Integrase core domain DUF2457 PF10446.9 GBG61371.1 - 0.042 13.0 2.9 0.099 11.8 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-H2C2 PF09337.10 GBG61371.1 - 0.13 12.5 0.2 0.34 11.2 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger DUF1758 PF05585.12 GBG61371.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Dimer_Tnp_hAT PF05699.14 GBG61372.1 - 7.8e-07 28.8 0.4 3.8e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG61372.1 - 0.00035 21.1 0.0 0.0011 19.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG61372.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61372.1 - 0.0016 19.0 0.0 0.004 17.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG61372.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG61373.1 - 1.7e-28 99.7 0.1 3.5e-28 98.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61373.1 - 5.5e-27 93.7 0.0 1.2e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61373.1 - 9.2e-24 83.8 0.0 1.8e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61373.1 - 6.8e-18 65.0 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG61373.1 - 3.1e-16 59.2 0.0 1.1e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG61373.1 - 0.00014 22.0 0.0 0.0008 19.6 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 GBG61374.1 - 1.1e-18 67.6 0.0 1.8e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C2-C2_1 PF11618.8 GBG61375.1 - 7.5e-14 52.0 0.0 1.2e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 C2 PF00168.30 GBG61375.1 - 4.2e-07 30.2 0.0 7.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF4497 PF14924.6 GBG61375.1 - 0.008 16.6 0.0 0.026 15.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4497) PPR_3 PF13812.6 GBG61376.1 - 3.2e-32 110.4 0.8 8.4e-11 41.8 0.0 5.6 3 3 2 6 6 6 6 Pentatricopeptide repeat domain PPR_2 PF13041.6 GBG61376.1 - 3.8e-31 107.0 7.3 2.3e-07 30.9 0.0 7.3 2 2 5 7 7 7 6 PPR repeat family PPR_long PF17177.4 GBG61376.1 - 1.3e-19 70.4 1.6 2.1e-15 56.7 0.6 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GBG61376.1 - 1e-17 63.1 18.6 0.013 15.7 0.0 7.7 8 0 0 8 8 8 5 PPR repeat PPR_1 PF12854.7 GBG61376.1 - 6.6e-17 60.9 0.6 0.0019 17.8 0.0 5.5 5 0 0 5 5 5 3 PPR repeat MRP-S27 PF10037.9 GBG61376.1 - 0.041 12.7 0.7 0.82 8.5 0.1 2.5 2 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 RPM2 PF08579.11 GBG61376.1 - 0.047 14.1 0.0 1.3 9.4 0.0 2.8 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) Exog_C PF18026.1 GBG61376.1 - 0.071 13.2 0.0 15 5.8 0.0 3.1 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain TPR_19 PF14559.6 GBG61376.1 - 0.12 12.9 0.0 1.4 9.5 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DEK_C PF08766.11 GBG61377.1 - 0.18 11.7 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain zf-CCHC PF00098.23 GBG61378.1 - 3.2e-06 27.0 3.2 3.2e-06 27.0 3.2 1.9 2 0 0 2 2 2 1 Zinc knuckle PTPRCAP PF15713.5 GBG61378.1 - 0.0019 18.5 17.6 0.0033 17.7 17.6 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated zf-CCHC_2 PF13696.6 GBG61378.1 - 0.034 14.0 2.2 0.065 13.1 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Zip PF02535.22 GBG61378.1 - 0.051 12.8 1.6 0.078 12.2 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2457 PF10446.9 GBG61378.1 - 0.055 12.6 16.3 0.098 11.8 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SAPS PF04499.15 GBG61378.1 - 0.95 8.2 4.3 1.4 7.6 4.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sigma70_ner PF04546.13 GBG61378.1 - 1.6 8.6 11.6 4.4 7.1 11.6 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region Na_trans_assoc PF06512.13 GBG61378.1 - 3.8 7.8 12.1 6.9 6.9 12.1 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated RR_TM4-6 PF06459.12 GBG61378.1 - 3.9 7.2 10.4 6.3 6.5 10.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Afi1 PF07792.12 GBG61378.1 - 5 7.6 8.2 8.7 6.8 8.2 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PPR_3 PF13812.6 GBG61379.1 - 5.1e-31 106.5 0.4 3.3e-10 39.9 0.0 5.8 3 3 2 6 6 6 6 Pentatricopeptide repeat domain PPR_2 PF13041.6 GBG61379.1 - 6.5e-31 106.3 4.1 4.5e-07 30.0 0.0 7.4 2 2 5 7 7 7 6 PPR repeat family PPR_long PF17177.4 GBG61379.1 - 1.3e-18 67.1 0.2 3.6e-14 52.6 0.0 2.4 1 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GBG61379.1 - 3.9e-18 64.9 0.2 0.0015 18.2 0.0 5.8 5 0 0 5 5 5 3 PPR repeat PPR PF01535.20 GBG61379.1 - 6.6e-18 63.6 15.3 0.0032 17.6 0.0 7.9 8 0 0 8 8 8 5 PPR repeat Exog_C PF18026.1 GBG61379.1 - 0.075 13.1 0.0 17 5.5 0.0 3.4 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain TPR_19 PF14559.6 GBG61379.1 - 0.097 13.2 0.0 0.47 11.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP13 PF12921.7 GBG61379.1 - 0.12 12.2 0.0 4.7 7.1 0.0 2.9 2 1 0 2 2 2 0 Mitochondrial ATPase expression HABP4_PAI-RBP1 PF04774.15 GBG61380.1 - 1.4e-20 74.2 17.0 1.4e-20 74.2 17.0 3.0 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 GBG61380.1 - 0.00024 21.9 6.0 0.00024 21.9 6.0 5.4 3 2 0 3 3 3 1 Stm1 Phage_TAC_8 PF10666.9 GBG61380.1 - 0.18 12.1 2.4 0.27 11.5 2.4 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 RT_RNaseH_2 PF17919.1 GBG61381.1 - 2.6e-16 59.5 0.0 7.2e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61381.1 - 1.5e-13 51.0 0.0 3.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61381.1 - 3.1e-11 43.2 0.0 5.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NOP19 PF10863.8 GBG61381.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Nucleolar protein 19 RVT_1 PF00078.27 GBG61382.1 - 0.05 13.1 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RPGR1_C PF18111.1 GBG61383.1 - 3.9e-08 33.4 0.0 5.6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Retinitis pigmentosa G-protein regulator interacting C-terminal Myb_DNA-bind_4 PF13837.6 GBG61384.1 - 3e-05 24.3 2.2 3e-05 24.3 2.2 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG61384.1 - 0.012 15.7 1.3 0.017 15.2 0.2 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain NAM-associated PF14303.6 GBG61384.1 - 0.055 14.2 0.1 0.1 13.3 0.1 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain MADF_DNA_bdg PF10545.9 GBG61384.1 - 3.8 7.9 6.1 1.1 9.6 0.5 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like IQ PF00612.27 GBG61385.1 - 6.5e-05 22.4 7.5 0.0095 15.7 3.6 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif HAD_2 PF13419.6 GBG61386.1 - 7.8e-20 71.7 0.0 1.4e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.32 GBG61386.1 - 1.8e-19 69.7 1.0 0.00016 22.4 0.0 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Hydrolase PF00702.26 GBG61386.1 - 9e-13 49.0 0.0 1.4e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ANAPC4_WD40 PF12894.7 GBG61386.1 - 5.1e-07 29.9 0.0 0.12 12.6 0.0 3.6 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hydrolase_like PF13242.6 GBG61386.1 - 2e-06 27.8 0.0 4.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GBG61386.1 - 0.00058 20.3 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Lactonase PF10282.9 GBG61386.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller PRELI PF04707.14 GBG61387.1 - 9.7e-46 155.4 0.0 1.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family DUF5446 PF17522.2 GBG61387.1 - 0.0064 16.6 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5446) Hs1pro-1_C PF07014.12 GBG61387.1 - 0.16 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus HSP70 PF00012.20 GBG61388.1 - 5.8e-66 222.9 0.2 6.3e-66 222.8 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG61388.1 - 4e-05 22.6 0.4 4.6e-05 22.4 0.4 1.1 1 0 0 1 1 1 1 MreB/Mbl protein DUF3220 PF11516.8 GBG61388.1 - 0.073 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Thioredox_DsbH PF03190.15 GBG61388.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Sel1 PF08238.12 GBG61389.1 - 1.2e-07 32.1 0.0 3.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Sel1 repeat Thioredoxin PF00085.20 GBG61390.1 - 2.4e-07 30.7 0.0 4.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Pep1_7 PF17232.2 GBG61390.1 - 0.19 12.2 9.4 0.13 12.7 4.7 2.7 2 0 0 2 2 2 0 Elicitor peptide 1-7 E7 PF00527.18 GBG61390.1 - 2 8.7 9.4 2.7 8.3 3.7 2.9 2 0 0 2 2 2 0 E7 protein, Early protein Lir1 PF07207.11 GBG61391.1 - 5.5e-27 94.6 1.9 4.5e-15 56.1 0.1 2.5 2 1 0 2 2 2 2 Light regulated protein Lir1 DUF2749 PF10907.8 GBG61391.1 - 3.7 7.8 5.4 2.3 8.4 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) Histone PF00125.24 GBG61392.1 - 6.1e-38 130.1 0.2 2.5e-37 128.2 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 ADK_lid PF05191.14 GBG61392.1 - 0.097 12.7 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid CBFD_NFYB_HMF PF00808.23 GBG61392.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_pol_phi PF04931.13 GBG61392.1 - 5.1 5.1 6.9 6.7 4.7 6.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_11 PF08241.12 GBG61394.1 - 2.2e-18 66.7 0.0 4.2e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG61394.1 - 6.1e-17 62.1 0.0 1.3e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG61394.1 - 1.7e-12 47.9 0.0 3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG61394.1 - 8.6e-11 41.9 0.0 2.6e-10 40.3 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG61394.1 - 3.6e-09 36.7 0.0 7.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG61394.1 - 5.5e-09 35.7 0.0 1.2e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GBG61394.1 - 1.8e-06 27.6 0.0 3.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 GBG61394.1 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DUF938 PF06080.12 GBG61394.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_11 PF08241.12 GBG61395.1 - 3.4e-16 59.6 0.0 8.9e-07 29.5 0.0 2.8 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GBG61395.1 - 1.6e-15 57.5 0.0 2.1e-07 31.5 0.1 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GBG61395.1 - 7e-13 49.2 0.0 1.9e-06 28.5 0.0 2.7 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GBG61395.1 - 1.3e-12 47.9 0.0 2.6e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG61395.1 - 1.9e-08 34.3 0.0 0.00054 19.8 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Ubie_methyltran PF01209.18 GBG61395.1 - 3.4e-07 29.8 0.0 2e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family zf-CCHC PF00098.23 GBG61395.1 - 0.00012 21.9 3.7 0.00025 21.0 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle MTS PF05175.14 GBG61395.1 - 0.00074 19.1 0.1 0.016 14.8 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase small domain Myc_N PF01056.18 GBG61395.1 - 0.0025 17.8 5.0 0.0025 17.8 5.0 2.4 2 0 0 2 2 2 1 Myc amino-terminal region Methyltransf_24 PF13578.6 GBG61395.1 - 0.018 16.0 0.1 0.093 13.8 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF4667 PF15700.5 GBG61395.1 - 0.029 14.5 1.0 0.029 14.5 1.0 2.8 2 1 0 2 2 1 0 Domain of unknown function (DUF4667) zf-CCHC_2 PF13696.6 GBG61395.1 - 0.091 12.6 1.7 0.16 11.8 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle PV-1 PF06637.11 GBG61395.1 - 0.16 10.7 12.7 0.27 10.0 12.7 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Shadoo PF14999.6 GBG61395.1 - 1 9.5 12.4 0.19 11.8 7.8 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DDHD PF02862.17 GBG61395.1 - 1.2 9.3 8.5 2.7 8.1 0.2 2.5 2 0 0 2 2 2 0 DDHD domain AAA_23 PF13476.6 GBG61395.1 - 2.5 8.6 12.7 0.76 10.2 7.9 2.1 2 0 0 2 2 2 0 AAA domain Androgen_recep PF02166.16 GBG61395.1 - 4.7 6.0 15.4 7.8 5.2 15.4 1.2 1 0 0 1 1 1 0 Androgen receptor DUF3446 PF11928.8 GBG61395.1 - 4.7 7.6 24.3 0.11 12.8 7.9 3.5 3 0 0 3 3 3 0 Early growth response N-terminal domain FAM76 PF16046.5 GBG61396.1 - 0.011 15.1 8.0 0.014 14.7 8.0 1.1 1 0 0 1 1 1 0 FAM76 protein SlyX PF04102.12 GBG61396.1 - 0.062 13.9 0.9 0.062 13.9 0.9 3.6 3 2 0 3 3 3 0 SlyX TAF4 PF05236.14 GBG61396.1 - 1.3 8.7 15.6 0.71 9.6 13.5 1.6 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family APG6_N PF17675.1 GBG61396.1 - 1.5 9.4 25.0 0.56 10.7 1.4 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4666 PF15697.5 GBG61396.1 - 1.7 9.4 6.0 0.97 10.2 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) MRP-S26 PF14943.6 GBG61396.1 - 4.1 7.3 14.6 39 4.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 UPF0242 PF06785.11 GBG61396.1 - 8.1 6.5 20.2 7.7e+02 0.0 20.2 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Chalcone_2 PF16035.5 GBG61397.1 - 1.2e-09 38.2 0.1 6.2e-08 32.7 0.1 2.0 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 GBG61397.1 - 5.2e-09 36.4 0.0 4e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Chalcone isomerase-like Chalcone PF02431.15 GBG61397.1 - 7.2e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 1 0 1 1 1 1 Chalcone-flavanone isomerase Cobl PF09469.10 GBG61397.1 - 0.031 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain WD40 PF00400.32 GBG61398.1 - 9.5e-10 38.9 20.6 0.088 13.7 0.0 8.5 9 0 0 9 9 9 4 WD domain, G-beta repeat Nup160 PF11715.8 GBG61398.1 - 0.00016 20.5 0.1 0.32 9.6 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GBG61398.1 - 0.00044 20.5 0.0 27 5.1 0.0 5.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Chromo PF00385.24 GBG61399.1 - 3.7e-07 30.0 0.2 1.5e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain V-SNARE_C PF12352.8 GBG61400.1 - 2e-12 47.2 1.9 2e-12 47.2 1.9 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GBG61400.1 - 0.00034 20.5 3.7 0.0056 16.6 0.3 2.3 2 0 0 2 2 2 1 Sec20 GCP_N_terminal PF17681.1 GBG61400.1 - 0.013 15.2 2.1 0.021 14.5 1.5 1.5 1 1 1 2 2 2 0 Gamma tubulin complex component N-terminal Syntaxin-6_N PF09177.11 GBG61400.1 - 0.024 15.2 2.9 0.84 10.2 0.4 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Laminin_I PF06008.14 GBG61400.1 - 0.033 13.9 0.9 0.16 11.6 0.0 2.1 1 1 1 2 2 2 0 Laminin Domain I Laminin_II PF06009.12 GBG61400.1 - 0.034 14.1 3.9 2.6 8.1 0.1 3.2 1 1 2 3 3 3 0 Laminin Domain II NleF_casp_inhib PF16809.5 GBG61400.1 - 0.036 14.0 0.2 0.11 12.5 0.1 1.7 1 1 0 2 2 2 0 NleF caspase inhibitor ABC_tran_CTD PF16326.5 GBG61400.1 - 0.038 14.2 2.3 0.34 11.2 0.1 2.7 3 0 0 3 3 3 0 ABC transporter C-terminal domain DHR10 PF18595.1 GBG61400.1 - 0.086 12.9 2.9 0.83 9.7 0.2 2.8 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Allexi_40kDa PF05549.11 GBG61400.1 - 0.089 12.3 2.0 0.65 9.5 0.1 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Pdase_C33_assoc PF14756.6 GBG61400.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 1 1 1 2 2 2 0 Peptidase_C33-associated domain Snf7 PF03357.21 GBG61400.1 - 0.17 11.5 2.4 12 5.5 0.5 2.4 2 0 0 2 2 2 0 Snf7 SYCE1 PF15233.6 GBG61400.1 - 0.19 11.8 4.7 2.6 8.1 0.1 2.8 2 1 0 3 3 3 0 Synaptonemal complex central element protein 1 Sec34 PF04136.15 GBG61400.1 - 0.34 10.8 4.0 4.1 7.3 0.4 2.4 1 1 0 2 2 2 0 Sec34-like family Hrs_helical PF12210.8 GBG61400.1 - 0.8 10.3 4.2 1.7 9.2 1.2 2.3 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate MATH PF00917.26 GBG61401.1 - 8e-30 103.3 3.6 7.4e-10 39.0 0.0 4.4 4 0 0 4 4 4 4 MATH domain FancD2 PF14631.6 GBG61401.1 - 1.4e-12 45.9 0.1 0.00048 17.7 0.0 4.0 4 0 0 4 4 4 3 Fanconi anaemia protein FancD2 nuclease CALCOCO1 PF07888.11 GBG61401.1 - 0.00032 19.7 33.6 0.00053 19.0 33.6 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.12 GBG61401.1 - 0.017 15.7 24.0 0.17 12.5 1.1 6.0 3 1 3 6 6 6 0 SlyX AAA_13 PF13166.6 GBG61401.1 - 0.82 8.2 15.9 1.6 7.3 15.9 1.4 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 GBG61401.1 - 0.96 6.9 27.9 1.6 6.2 27.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lectin_N PF03954.14 GBG61401.1 - 1.2 8.9 4.3 0.72 9.6 1.1 2.3 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Spc7 PF08317.11 GBG61401.1 - 3.8 6.3 33.4 3.8 6.3 13.9 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF5082 PF16888.5 GBG61401.1 - 4.9 7.5 16.0 30 4.9 11.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) ING PF12998.7 GBG61401.1 - 8.4 7.0 10.4 11 6.7 9.1 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.12 GBG61401.1 - 8.7 6.4 12.8 42 4.2 4.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_4 PF07721.14 GBG61402.1 - 0.19 12.4 9.1 7.1 7.6 0.6 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Ctr PF04145.15 GBG61402.1 - 7.6 7.1 7.2 7.7 7.1 0.4 2.3 2 0 0 2 2 2 0 Ctr copper transporter family TCP PF03634.13 GBG61402.1 - 9 6.8 17.8 3.4 8.2 3.8 2.3 2 0 0 2 2 2 0 TCP family transcription factor Dimer_Tnp_hAT PF05699.14 GBG61403.1 - 0.00046 19.9 0.3 0.00098 18.9 0.3 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nop53 PF07767.11 GBG61405.1 - 0.038 13.4 6.5 0.05 13.0 6.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SPT6_acidic PF14632.6 GBG61405.1 - 0.15 12.7 13.5 0.24 12.0 13.5 1.4 1 1 0 1 1 1 0 Acidic N-terminal SPT6 RRN3 PF05327.11 GBG61405.1 - 0.47 8.9 4.0 0.58 8.6 4.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pectinesterase PF01095.19 GBG61406.1 - 3.2e-62 209.9 1.7 4.1e-62 209.6 1.7 1.1 1 0 0 1 1 1 1 Pectinesterase SDA1 PF05285.12 GBG61407.1 - 1 8.7 12.5 1.2 8.4 12.5 1.1 1 0 0 1 1 1 0 SDA1 Menin PF05053.13 GBG61407.1 - 1.6 7.0 10.4 2.1 6.6 10.4 1.1 1 0 0 1 1 1 0 Menin Vps5 PF09325.10 GBG61408.1 - 2.4e-30 105.8 10.3 3.2e-30 105.4 10.3 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 GBG61408.1 - 1.3e-28 99.3 1.9 4.1e-28 97.6 0.1 2.5 2 1 0 2 2 2 1 PX domain Tektin PF03148.14 GBG61408.1 - 0.0066 15.2 0.5 0.0066 15.2 0.5 2.6 2 1 0 2 2 2 1 Tektin family BAR_3_WASP_bdg PF10456.9 GBG61408.1 - 0.071 12.6 6.2 0.88 9.0 6.2 2.3 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DUF4140 PF13600.6 GBG61408.1 - 0.093 13.2 8.4 0.78 10.2 0.8 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LMBR1 PF04791.16 GBG61408.1 - 0.11 11.3 2.9 0.16 10.9 2.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FlgM PF04316.13 GBG61408.1 - 0.66 10.4 4.0 0.3 11.5 0.6 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF4337 PF14235.6 GBG61408.1 - 0.7 10.0 11.0 1.5 8.9 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) UPF0242 PF06785.11 GBG61408.1 - 1.8 8.6 15.9 3.5 7.7 6.5 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FAA_hydro_N_2 PF18288.1 GBG61408.1 - 2 8.9 8.3 4.9 7.7 0.2 3.5 2 1 2 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 WD40 PF00400.32 GBG61409.1 - 3.8e-17 62.3 14.0 0.0012 19.6 0.5 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG61409.1 - 8.1e-12 45.3 0.0 0.0017 18.6 0.0 5.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GBG61409.1 - 0.25 11.3 3.1 21 5.2 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Beta-Casp PF10996.8 GBG61410.1 - 4.1e-23 81.8 0.0 1.1e-22 80.4 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 GBG61410.1 - 1.1e-18 67.4 0.0 2.2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 GBG61410.1 - 3e-13 49.5 0.6 5.9e-13 48.5 0.6 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 GBG61410.1 - 5.8e-10 39.5 0.0 1.6e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GBG61410.1 - 5.9e-09 35.7 0.3 3.3e-08 33.3 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GBG61410.1 - 0.021 14.7 0.2 0.12 12.2 0.2 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 GBG61410.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative beta-lactamase-like family GYF PF02213.16 GBG61411.1 - 7.5e-11 41.5 0.0 1.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 GYF domain Aldolase_II PF00596.21 GBG61413.1 - 2.9e-26 92.5 0.1 3.7e-13 49.8 0.1 2.3 2 0 0 2 2 2 2 Class II Aldolase and Adducin N-terminal domain RVT_1 PF00078.27 GBG61413.1 - 4.7e-22 78.6 0.0 1.8e-16 60.4 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Focadhesin PF11229.8 GBG61413.1 - 0.0057 14.9 0.0 1.3 7.1 0.0 2.1 1 1 1 2 2 2 2 Focadhesin Pkinase PF00069.25 GBG61414.1 - 2.6e-72 243.4 0.0 3.6e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61414.1 - 2.4e-36 125.3 1.0 2.7e-36 125.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 GBG61414.1 - 8.6e-24 81.3 3.6 1e-05 24.7 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 GBG61414.1 - 1.2e-21 74.8 1.7 3.6e-05 23.3 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GBG61414.1 - 2.9e-19 67.6 5.7 1.5e-05 24.2 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 GBG61414.1 - 5.5e-19 68.4 0.3 1.7e-08 34.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GBG61414.1 - 9.5e-11 41.4 3.3 0.00025 20.8 0.1 3.5 2 1 1 3 3 3 3 EF-hand domain pair Kinase-like PF14531.6 GBG61414.1 - 1.9e-08 34.0 0.1 2.2e-06 27.2 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 GBG61414.1 - 2.1e-07 30.5 0.1 4.2e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG61414.1 - 0.00049 20.1 0.0 0.74 9.7 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.9 GBG61414.1 - 0.00079 19.7 0.0 0.074 13.4 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GBG61414.1 - 0.026 14.7 4.6 7 6.9 1.1 4.4 3 1 2 5 5 5 0 Dockerin type I domain EF-hand_4 PF12763.7 GBG61414.1 - 0.027 14.4 1.3 3.3 7.7 0.1 3.4 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 GBG61414.1 - 0.32 11.4 1.1 4.4 7.7 0.0 3.1 3 1 0 3 3 3 0 EF-hand domain Presenilin PF01080.17 GBG61416.1 - 0.0061 15.4 0.9 0.0067 15.2 0.9 1.1 1 0 0 1 1 1 1 Presenilin V_ATPase_I PF01496.19 GBG61416.1 - 1.8 6.4 4.9 2.2 6.1 4.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SpoIIP PF07454.11 GBG61416.1 - 4.2 6.7 8.4 5.9 6.3 8.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nop14 PF04147.12 GBG61416.1 - 5.9 5.0 14.1 7.3 4.7 14.1 1.0 1 0 0 1 1 1 0 Nop14-like family Connexin PF00029.19 GBG61416.1 - 8.8 6.0 9.5 14 5.4 9.5 1.2 1 0 0 1 1 1 0 Connexin Cpn60_TCP1 PF00118.24 GBG61417.1 - 4.1e-147 490.8 8.2 4.6e-147 490.6 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SHQ1 PF04925.15 GBG61418.1 - 2.4e-06 27.2 0.0 5.7e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 SHQ1 protein ADH_N PF08240.12 GBG61419.1 - 1.5e-24 86.0 1.4 2.9e-24 85.1 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GBG61419.1 - 2.9e-18 66.1 0.1 6e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 GBG61419.1 - 0.0015 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 GBG61419.1 - 0.0036 17.6 0.0 0.0059 16.9 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 GBG61419.1 - 0.0049 16.2 0.1 0.0081 15.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GBG61419.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Reo_sigma1 PF01664.16 GBG61419.1 - 0.046 13.0 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Reovirus viral attachment protein sigma 1 Mpv17_PMP22 PF04117.12 GBG61420.1 - 1.5e-17 63.6 0.1 2.9e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family SGL PF08450.12 GBG61421.1 - 0.0062 16.1 0.0 3.9 7.0 0.0 3.7 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 GBG61421.1 - 0.12 11.6 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller AAA PF00004.29 GBG61423.1 - 5.3e-05 23.7 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 GBG61423.1 - 7.6e-05 22.7 0.2 0.33 10.8 0.0 2.4 2 0 0 2 2 2 2 NTPase AAA_30 PF13604.6 GBG61423.1 - 0.00026 20.7 0.1 0.00058 19.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GBG61423.1 - 0.0021 18.0 0.0 0.006 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG61423.1 - 0.0024 18.3 0.0 0.0079 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 GBG61423.1 - 0.0038 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 GBG61423.1 - 0.0076 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GBG61423.1 - 0.015 15.9 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GBG61423.1 - 0.027 14.7 0.1 0.092 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GBG61423.1 - 0.028 14.6 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 GBG61423.1 - 0.038 13.6 0.1 0.077 12.6 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiA PF01656.23 GBG61423.1 - 0.049 13.7 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TIP49 PF06068.13 GBG61423.1 - 0.052 12.7 0.1 0.081 12.1 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 GBG61423.1 - 0.058 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 GBG61423.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GBG61423.1 - 0.074 13.4 0.2 0.19 12.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 GBG61423.1 - 0.075 13.5 0.0 0.33 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 GBG61423.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG61423.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase KTI12 PF08433.10 GBG61423.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_31 PF13614.6 GBG61423.1 - 0.19 11.6 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 GBG61423.1 - 0.2 11.4 0.0 0.44 10.2 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 GBG61423.1 - 0.21 12.0 0.0 0.63 10.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ArsA_ATPase PF02374.15 GBG61423.1 - 0.22 10.7 0.1 0.33 10.1 0.1 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase DUF4659 PF15558.6 GBG61426.1 - 0.038 12.9 4.6 0.045 12.6 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) RT_RNaseH_2 PF17919.1 GBG61427.1 - 1.2e-139 455.3 0.0 2.8e-33 113.9 0.0 6.0 5 0 0 5 5 5 5 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61427.1 - 1.2e-136 446.6 4.5 1.5e-29 102.4 0.1 6.4 6 0 0 6 6 6 5 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61427.1 - 3.7e-48 164.0 0.9 4.7e-33 114.6 0.1 4.5 4 0 0 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61427.1 - 7.6e-44 148.7 0.2 6.3e-15 55.4 0.0 4.3 3 0 0 3 3 3 3 Integrase core domain Integrase_H2C2 PF17921.1 GBG61427.1 - 1.6e-37 127.4 3.3 2.2e-17 62.9 0.5 3.7 3 0 0 3 3 3 3 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG61427.1 - 6.8e-10 39.5 0.8 0.00035 21.1 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease RVP_2 PF08284.11 GBG61427.1 - 8.9e-08 32.0 0.0 1.5e-05 24.8 0.0 2.8 3 0 0 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG61427.1 - 1.2e-07 32.1 2.7 0.0027 18.2 0.0 3.5 4 0 0 4 4 3 2 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG61427.1 - 2.9e-05 24.2 0.2 0.085 13.1 0.1 2.8 2 0 0 2 2 2 2 H2C2 zinc finger DUF1758 PF05585.12 GBG61427.1 - 0.033 14.0 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG61427.1 - 0.11 12.3 0.0 2.2 8.1 0.0 3.0 3 0 0 3 3 3 0 Aspartyl protease DUF659 PF04937.15 GBG61428.1 - 4.7e-33 114.2 0.1 7e-33 113.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61428.1 - 0.00034 20.3 0.2 0.00069 19.4 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Sec16_C PF12931.7 GBG61429.1 - 5.9e-56 190.3 0.0 7.8e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 GBG61429.1 - 6.8e-16 58.9 0.0 1.3e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region RT_RNaseH_2 PF17919.1 GBG61430.1 - 2.9e-20 72.2 0.0 7.6e-20 70.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61430.1 - 2.5e-18 66.3 0.0 8.9e-18 64.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61430.1 - 7.2e-09 35.5 0.0 2.5e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG61430.1 - 0.0002 21.9 0.0 0.0005 20.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61430.1 - 0.00053 20.5 0.0 0.0018 18.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_5 PF14787.6 GBG61430.1 - 0.016 14.9 1.8 0.038 13.7 1.8 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG61430.1 - 0.47 10.6 4.0 1.2 9.3 4.0 1.7 1 0 0 1 1 1 0 Zinc knuckle BAR_3 PF16746.5 GBG61431.1 - 1.1e-11 45.0 6.1 1.6e-11 44.4 6.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 GBG61431.1 - 1.8e-11 44.2 2.9 2.5e-11 43.7 2.9 1.2 1 0 0 1 1 1 1 BAR domain SH3BP5 PF05276.14 GBG61431.1 - 0.031 14.1 0.4 0.058 13.2 0.4 1.3 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Arfaptin PF06456.13 GBG61431.1 - 0.053 13.1 3.4 0.41 10.2 3.4 2.0 1 1 0 1 1 1 0 Arfaptin-like domain Bac_DnaA_C PF08299.11 GBG61432.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix TFA2_Winged_2 PF18121.1 GBG61434.1 - 5.4e-14 51.6 0.1 1.8e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 GBG61434.1 - 1.1e-11 44.8 0.1 3.3e-11 43.3 0.1 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain TraV PF09676.10 GBG61434.1 - 0.33 11.9 1.6 0.78 10.7 1.6 1.6 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Pkinase PF00069.25 GBG61435.1 - 7.5e-39 133.7 0.0 2.1e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61435.1 - 4.6e-16 58.9 0.0 1.6e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Retrotrans_gag PF03732.17 GBG61436.1 - 0.0027 18.0 0.4 0.016 15.4 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG61439.1 - 4.6e-23 81.1 0.0 9e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61439.1 - 1.6e-19 70.3 0.0 2.5e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61439.1 - 1.9e-14 53.8 0.0 4.3e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG61439.1 - 8.8e-07 28.8 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61439.1 - 1e-06 29.2 0.0 2.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61439.1 - 4.5e-06 27.1 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61439.1 - 0.00026 20.8 0.0 0.00062 19.5 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG61440.1 - 1.6e-28 99.7 0.2 2.2e-28 99.3 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61440.1 - 4e-26 91.0 0.0 7.5e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61440.1 - 1.5e-16 60.5 0.0 2.9e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDH1_2_SANT_HL1 PF18375.1 GBG61440.1 - 0.097 13.4 0.0 0.28 11.9 0.0 1.7 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 APG17 PF04108.12 GBG61440.1 - 0.19 10.8 0.0 3.1 6.8 0.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF659 PF04937.15 GBG61441.1 - 2e-34 118.7 0.1 2e-34 118.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61441.1 - 5.1e-08 32.6 0.5 1.4e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF5462 PF17547.2 GBG61441.1 - 0.13 11.6 0.3 0.31 10.4 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5462) Vps36-NZF-N PF16988.5 GBG61443.1 - 0.024 14.0 0.6 0.086 12.2 0.6 2.0 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-tcix PF14952.6 GBG61443.1 - 0.04 13.5 3.7 0.087 12.5 3.7 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Glyco_hydro_2_N PF02837.18 GBG61443.1 - 0.074 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain zf-ribbon_3 PF13248.6 GBG61443.1 - 0.24 10.9 3.0 5.7 6.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-MYND PF01753.18 GBG61443.1 - 0.61 10.2 6.0 1.9 8.7 6.0 1.9 1 0 0 1 1 1 0 MYND finger AC_N PF16214.5 GBG61443.1 - 1.2 8.1 10.9 0.02 14.1 1.8 2.1 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF3499 PF12005.8 GBG61443.1 - 2.9 8.5 10.3 1 10.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) CTU2 PF10288.9 GBG61443.1 - 3.6 7.9 12.4 0.13 12.5 2.8 3.0 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF3801 PF12687.7 GBG61443.1 - 3.8 7.5 9.5 6.3 6.8 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Glyco_hydro_31 PF01055.26 GBG61444.1 - 1.3e-52 179.5 0.2 5.1e-52 177.5 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 DUF2282 PF10048.9 GBG61445.1 - 0.15 12.1 0.1 5.7 7.0 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2282) NTP_transferase PF00483.23 GBG61446.1 - 9.5e-68 228.4 0.0 1.3e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 GBG61446.1 - 2.6e-05 24.6 0.0 5.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain RVT_1 PF00078.27 GBG61448.1 - 2.3e-27 95.9 0.1 4e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61448.1 - 1.4e-15 57.1 0.0 6.8e-14 51.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61448.1 - 0.00014 22.1 0.0 0.00034 20.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CENP-Q PF13094.6 GBG61449.1 - 0.032 14.4 10.1 0.047 13.9 10.1 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Herpes_UL25 PF01499.16 GBG61449.1 - 0.1 11.1 1.8 0.15 10.5 1.2 1.4 1 1 1 2 2 2 0 Herpesvirus UL25 family Syntaxin-6_N PF09177.11 GBG61449.1 - 0.27 11.8 8.1 0.41 11.2 3.4 2.3 1 1 0 2 2 2 0 Syntaxin 6, N-terminal NTS_2 PF15448.6 GBG61449.1 - 2 8.9 0.0 2 8.9 0.0 3.2 4 0 0 4 4 4 0 N-terminal segments of P. falciparum erythrocyte membrane protein gag-asp_proteas PF13975.6 GBG61450.1 - 3.5e-07 30.7 0.2 7.1e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61450.1 - 1.3e-05 25.8 0.2 3e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG61450.1 - 0.00015 21.5 0.1 0.00023 20.9 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG61450.1 - 0.0058 16.4 0.1 0.0098 15.7 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease BetaGal_dom4_5 PF13364.6 GBG61452.1 - 5.7e-05 23.7 0.0 0.0006 20.4 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain DNA_pack_N PF02500.15 GBG61452.1 - 0.24 11.2 1.8 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus O-antigen_lig PF13425.6 GBG61452.1 - 1 8.0 1.9 2 7.1 1.9 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Integrase_H2C2 PF17921.1 GBG61453.1 - 3.3e-17 62.3 0.3 8.6e-17 61.0 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG61453.1 - 2e-13 50.5 0.2 8.3e-13 48.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61453.1 - 3.5e-09 36.9 0.0 8.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG61453.1 - 4.6e-07 29.8 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG61453.1 - 0.00057 20.0 0.1 0.0014 18.8 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG61453.1 - 0.00083 18.9 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4187 PF13821.6 GBG61453.1 - 0.0034 17.1 1.0 0.011 15.5 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Chromo PF00385.24 GBG61453.1 - 0.0038 17.1 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CENP-K PF11802.8 GBG61453.1 - 0.027 14.1 2.0 0.046 13.3 2.0 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Retrotrans_gag PF03732.17 GBG61453.1 - 1 9.6 3.8 2.2 8.6 0.3 3.2 3 0 0 3 3 3 0 Retrotransposon gag protein DUF4407 PF14362.6 GBG61453.1 - 8 5.7 19.4 10 5.4 18.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RT_RNaseH_2 PF17919.1 GBG61456.1 - 4.2e-24 84.5 0.1 3.9e-23 81.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61456.1 - 1.8e-23 82.8 0.1 1e-22 80.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG61456.1 - 3.7e-07 30.7 0.0 8.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG61456.1 - 3.8e-07 30.0 0.0 7.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG61456.1 - 2.5e-05 24.8 0.0 6.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG61456.1 - 0.00017 21.6 0.0 0.00039 20.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG61456.1 - 0.0077 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease TolA_bind_tri PF16331.5 GBG61456.1 - 0.034 14.2 4.5 0.1 12.7 4.5 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation CAP PF00188.26 GBG61456.1 - 0.21 12.4 1.4 0.5 11.2 1.4 1.6 1 0 0 1 1 1 0 Cysteine-rich secretory protein family JIP_LZII PF16471.5 GBG61456.1 - 1.4 9.2 4.7 21 5.4 1.4 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 GBG61456.1 - 7.6 7.2 15.2 0.047 14.3 1.7 3.0 2 1 1 3 3 3 0 SlyX Glyco_hydro_35 PF01301.19 GBG61457.1 - 1.1e-105 353.7 0.0 1.5e-105 353.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 GBG61457.1 - 5.4e-06 26.0 0.0 4.3e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Beta-galactosidase DUF588 PF04535.12 GBG61458.1 - 4.1e-23 81.8 9.1 5e-23 81.6 9.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF588) MARVEL PF01284.23 GBG61458.1 - 3e-11 43.5 19.6 4.4e-11 43.0 19.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.12 GBG61458.1 - 0.036 13.7 1.4 0.036 13.7 1.4 2.5 1 1 1 2 2 2 0 SUR7/PalI family DUF373 PF04123.13 GBG61458.1 - 0.15 11.5 2.6 0.17 11.3 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) GntR PF00392.21 GBG61462.1 - 0.28 10.8 1.0 4.7 6.9 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family RVT_1 PF00078.27 GBG61463.1 - 7.1e-31 107.5 0.1 1.3e-30 106.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61463.1 - 1e-25 89.7 0.1 6.1e-25 87.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61463.1 - 1.3e-23 83.2 0.7 5.4e-23 81.3 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61463.1 - 2.7e-15 56.2 2.4 1.2e-14 54.2 1.0 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG61463.1 - 0.0027 17.9 0.3 0.0073 16.5 0.3 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF3450 PF11932.8 GBG61463.1 - 0.0074 15.6 2.9 0.015 14.6 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ACC_epsilon PF13822.6 GBG61463.1 - 0.11 13.2 1.8 0.37 11.5 1.8 1.9 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit FmiP_Thoc5 PF09766.9 GBG61463.1 - 1.1 8.4 5.0 2 7.6 5.0 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 gag-asp_proteas PF13975.6 GBG61465.1 - 0.00034 21.1 0.0 0.0012 19.3 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61465.1 - 0.00093 19.8 0.0 0.006 17.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG61465.1 - 0.014 15.6 0.4 0.056 13.7 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Roughex PF06020.11 GBG61465.1 - 2.9 6.9 9.5 0.16 11.1 4.3 1.4 2 0 0 2 2 2 0 Drosophila roughex protein EF-1_beta_acid PF10587.9 GBG61465.1 - 3.2 8.3 11.4 16 6.1 11.4 2.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Dev_Cell_Death PF10539.9 GBG61466.1 - 4.6e-45 152.6 0.2 6.9e-45 152.0 0.2 1.3 1 0 0 1 1 1 1 Development and cell death domain G-patch PF01585.23 GBG61467.1 - 1.9e-10 40.5 3.5 1.9e-10 40.5 3.5 2.5 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 GBG61467.1 - 1.2e-05 25.3 4.2 1.2e-05 25.3 4.2 3.8 4 0 0 4 4 4 1 G-patch domain ALMT PF11744.8 GBG61467.1 - 3.3 6.4 4.1 6.7 5.4 4.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter RRN3 PF05327.11 GBG61467.1 - 5.6 5.4 16.4 11 4.4 16.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RVT_1 PF00078.27 GBG61468.1 - 6.1e-27 94.6 0.1 1e-26 93.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61468.1 - 2.4e-07 30.6 0.0 5.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61468.1 - 2.6e-06 28.0 0.0 1.2e-05 25.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61468.1 - 0.0002 21.8 0.0 0.00071 20.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG61468.1 - 0.013 15.7 0.2 0.1 12.9 0.0 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG61468.1 - 0.022 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DSPc PF00782.20 GBG61469.1 - 1.8e-26 92.5 0.0 2.7e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 GBG61469.1 - 0.04 14.2 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 GBG61469.1 - 0.064 13.4 0.0 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Pkinase PF00069.25 GBG61470.1 - 1.3e-69 234.6 0.0 1.4e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61470.1 - 1.2e-28 100.2 0.0 1.5e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG61470.1 - 0.031 14.2 0.0 0.2 11.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 GBG61470.1 - 0.036 13.4 0.0 0.082 12.2 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 GBG61470.1 - 0.044 12.7 0.0 0.074 12.0 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain DUF1682 PF07946.14 GBG61471.1 - 4.4 6.4 14.4 8.5 5.5 14.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LCD1 PF09798.9 GBG61471.1 - 9 4.7 11.2 13 4.2 11.2 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein ArfGap PF01412.18 GBG61472.1 - 3.6e-05 23.8 3.0 9.1e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf TFIIA PF03153.13 GBG61472.1 - 8.4e-05 22.7 34.6 0.00016 21.8 34.6 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 GBG61472.1 - 7.7 3.5 22.7 10 3.1 22.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 GBG61473.1 - 0.00082 18.7 3.7 0.00082 18.7 3.7 2.5 3 0 0 3 3 3 1 ZIP Zinc transporter Connexin PF00029.19 GBG61473.1 - 0.0033 17.2 10.2 0.0033 17.2 10.2 1.7 2 0 0 2 2 2 1 Connexin Otopetrin PF03189.13 GBG61473.1 - 0.12 11.2 2.0 0.2 10.4 2.0 1.3 1 0 0 1 1 1 0 Otopetrin DUF2207 PF09972.9 GBG61473.1 - 0.2 10.4 4.0 0.36 9.5 4.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Vfa1 PF08432.10 GBG61473.1 - 0.42 10.9 37.8 0.055 13.8 29.7 2.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TMPIT PF07851.13 GBG61473.1 - 2.1 7.5 10.7 3.6 6.8 10.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Neur_chan_memb PF02932.16 GBG61473.1 - 5.6 6.9 16.8 0.15 12.1 9.0 2.3 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region EMC3_TMCO1 PF01956.16 GBG61473.1 - 8.1 6.2 12.0 16 5.2 12.0 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like BSMAP PF12280.8 GBG61473.1 - 8.7 6.5 10.8 0.85 9.8 3.6 2.7 3 0 0 3 3 3 0 Brain specific membrane anchored protein Fer2 PF00111.27 GBG61474.1 - 3.6e-15 55.7 0.3 6.9e-15 54.8 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RVT_1 PF00078.27 GBG61476.1 - 4.3e-26 91.8 0.6 9.5e-26 90.7 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61476.1 - 0.0079 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG61476.1 - 0.086 13.1 0.5 0.23 11.7 0.1 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein SCAMP PF04144.13 GBG61477.1 - 9.7e-41 140.0 17.8 1.2e-40 139.7 17.8 1.1 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.8 GBG61477.1 - 0.047 13.1 4.5 0.076 12.4 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF3974 PF13120.6 GBG61477.1 - 0.46 10.6 3.0 0.56 10.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) BRD4_CDT PF17105.5 GBG61477.1 - 0.74 9.5 2.9 1.8 8.2 2.9 1.6 1 1 0 1 1 1 0 C-terminal domain of bromodomain protein 4 YqzM PF14141.6 GBG61477.1 - 0.98 9.5 6.1 20 5.3 0.1 2.8 2 0 0 2 2 2 0 YqzM-like protein MerC PF03203.14 GBG61477.1 - 2 8.9 11.5 3.2 8.2 11.5 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein His_biosynth PF00977.21 GBG61478.1 - 8.8e-23 81.0 0.4 6.2e-13 48.7 0.1 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein His_biosynth PF00977.21 GBG61479.1 - 9.6e-23 80.8 0.4 6.5e-13 48.7 0.1 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein zf-TAZ PF02135.16 GBG61481.1 - 0.11 13.0 2.3 0.17 12.4 2.3 1.3 1 1 0 1 1 1 0 TAZ zinc finger TPR_2 PF07719.17 GBG61482.1 - 2.1e-27 93.0 15.6 8.8e-05 22.3 0.1 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 GBG61482.1 - 3.6e-26 89.9 9.3 0.00014 21.5 0.0 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 GBG61482.1 - 6.4e-22 75.9 8.8 0.0021 18.1 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 GBG61482.1 - 1.5e-20 72.6 0.2 2.1e-06 27.3 0.0 5.8 3 2 3 6 6 5 5 TPR repeat TPR_14 PF13428.6 GBG61482.1 - 1.2e-19 69.3 4.9 0.00016 22.2 0.1 6.9 3 2 3 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 GBG61482.1 - 8.8e-19 66.5 6.1 0.0006 20.0 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 GBG61482.1 - 1.3e-16 60.8 8.4 1.7e-06 28.4 0.4 4.8 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 GBG61482.1 - 1.4e-16 60.8 6.1 0.00011 22.7 0.1 5.4 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 GBG61482.1 - 2.4e-15 56.6 13.3 3e-06 27.4 1.1 5.1 2 2 3 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG61482.1 - 3.4e-08 33.6 7.1 0.011 16.0 0.5 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GBG61482.1 - 4.8e-08 32.5 2.6 0.27 11.4 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG61482.1 - 2.4e-07 30.8 0.4 0.092 12.9 0.1 3.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 GBG61482.1 - 1.7e-06 27.7 17.4 0.05 13.5 0.3 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG61482.1 - 9.6e-06 25.9 7.4 0.19 12.4 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat EF-hand_1 PF00036.32 GBG61482.1 - 1.3e-05 24.4 2.8 0.00017 20.9 0.6 3.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GBG61482.1 - 0.00013 21.7 0.4 0.0019 17.9 0.2 3.1 3 0 0 3 3 2 1 EF-hand domain EF-hand_7 PF13499.6 GBG61482.1 - 0.0026 18.2 0.1 0.014 15.8 0.0 2.3 2 0 0 2 2 1 1 EF-hand domain pair BTAD PF03704.17 GBG61482.1 - 0.0028 18.1 1.1 0.51 10.8 0.3 3.1 2 1 0 2 2 2 1 Bacterial transcriptional activator domain EF-hand_5 PF13202.6 GBG61482.1 - 0.0041 16.6 0.6 0.018 14.5 0.6 2.2 1 0 0 1 1 1 1 EF hand TPR_21 PF09976.9 GBG61482.1 - 0.0061 16.3 3.8 0.53 10.0 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 GBG61482.1 - 0.0078 16.3 1.2 1.7 8.8 0.0 3.6 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 GBG61482.1 - 0.016 14.6 0.4 5.8 6.2 0.3 3.2 1 1 2 3 3 3 0 MalT-like TPR region SRP_TPR_like PF17004.5 GBG61482.1 - 0.021 14.9 1.2 2.9 7.9 0.1 2.7 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_4 PF07721.14 GBG61482.1 - 0.14 12.8 4.9 23 6.0 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF4810 PF16068.5 GBG61482.1 - 0.36 11.4 3.4 1.2 9.8 0.1 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4810) DUF630 PF04783.12 GBG61482.1 - 0.71 10.1 3.1 1.3 9.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF630) Myb_DNA-binding PF00249.31 GBG61483.1 - 9.7e-06 25.7 0.0 9.7e-06 25.7 0.0 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain LSM PF01423.22 GBG61484.1 - 4.9e-21 74.2 0.0 6.2e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GBG61484.1 - 0.0059 16.7 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Ribosomal_S19e PF01090.19 GBG61485.1 - 3.4e-58 195.2 0.0 4.3e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RVT_1 PF00078.27 GBG61486.1 - 5.8e-37 127.4 0.1 1e-36 126.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61486.1 - 8e-31 106.0 0.0 8e-30 102.8 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61486.1 - 1.4e-30 105.7 0.1 1.9e-29 102.0 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61486.1 - 7.4e-19 67.6 0.3 1.8e-18 66.4 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61486.1 - 1.2e-17 64.2 0.0 3.4e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61486.1 - 0.0021 18.3 0.0 0.0059 16.8 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger VIR_N PF15912.5 GBG61486.1 - 5.4 6.5 7.2 14 5.2 7.2 1.7 1 0 0 1 1 1 0 Virilizer, N-terminal Rotamase PF00639.21 GBG61486.1 - 7.9 7.5 10.9 53 4.9 0.0 3.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain NOA36 PF06524.12 GBG61487.1 - 3.5 6.9 8.6 3.8 6.8 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.32 GBG61488.1 - 3.6e-05 24.4 0.0 0.00011 22.9 0.0 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG61488.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain RR_TM4-6 PF06459.12 GBG61490.1 - 4.8 6.9 43.2 7.1 6.4 43.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PrmA PF06325.13 GBG61491.1 - 1.5e-13 50.8 0.0 2.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GBG61491.1 - 7.5e-13 49.0 0.0 3.5e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG61491.1 - 4.6e-11 43.2 0.0 4.8e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG61491.1 - 7.1e-11 42.1 0.0 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG61491.1 - 1.5e-07 31.1 0.2 2.5e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 GBG61491.1 - 1.7e-06 28.0 0.1 2.9e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG61491.1 - 2.1e-06 27.7 0.0 7.7e-06 25.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG61491.1 - 3.5e-05 24.5 1.6 4.6e-05 24.1 0.0 2.1 3 0 0 3 3 1 1 Methyltransferase domain TehB PF03848.14 GBG61491.1 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Met_10 PF02475.16 GBG61491.1 - 0.00028 20.7 0.1 0.0005 19.9 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.16 GBG61491.1 - 0.00044 20.1 0.0 0.00078 19.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 GBG61491.1 - 0.00047 21.2 0.0 0.0026 18.7 0.0 2.3 3 0 0 3 3 1 1 Methyltransferase domain CMAS PF02353.20 GBG61491.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GidB PF02527.15 GBG61491.1 - 0.0018 17.7 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_9 PF08003.11 GBG61491.1 - 0.0038 16.2 0.1 0.006 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 GBG61491.1 - 0.0058 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GBG61491.1 - 0.0096 15.7 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 GBG61491.1 - 0.054 13.1 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.9 GBG61491.1 - 0.087 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 GBG61491.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 HpaB PF03241.13 GBG61491.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Ribosomal_60s PF00428.19 GBG61492.1 - 8.8e-24 83.9 3.0 1.3e-23 83.4 3.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Exo_endo_phos PF03372.23 GBG61493.1 - 8.1e-11 41.9 1.0 1.7e-10 40.8 1.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG61493.1 - 0.0053 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase MAM33 PF02330.16 GBG61494.1 - 7.3e-38 130.6 0.0 9.4e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Exo_endo_phos PF03372.23 GBG61495.1 - 8.6e-06 25.4 0.5 1.7e-05 24.4 0.5 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RT_RNaseH PF17917.1 GBG61496.1 - 3.5e-18 65.8 0.0 7.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61496.1 - 4.7e-11 42.6 0.1 8.2e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61496.1 - 1.4e-10 41.1 0.0 2.6e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase W2 PF02020.18 GBG61497.1 - 4.8e-36 122.8 9.0 9.4e-22 77.0 2.3 3.6 3 0 0 3 3 3 2 eIF4-gamma/eIF5/eIF2-epsilon DUF4990 PF16380.5 GBG61497.1 - 8.3e-06 26.0 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function FliG_C PF01706.16 GBG61497.1 - 0.002 18.3 3.1 0.43 10.8 0.5 4.3 2 2 2 4 4 4 1 FliG C-terminal domain RHSP PF07999.11 GBG61497.1 - 0.0098 14.7 2.5 2.4 6.9 0.1 2.7 3 0 0 3 3 3 2 Retrotransposon hot spot protein DUF2239 PF09998.9 GBG61497.1 - 0.019 14.8 0.4 0.06 13.1 0.4 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) PP_kinase PF02503.17 GBG61497.1 - 0.026 14.1 0.1 9.6 5.7 0.0 2.5 2 0 0 2 2 2 0 Polyphosphate kinase middle domain Vps39_1 PF10366.9 GBG61497.1 - 0.11 12.8 1.5 24 5.3 0.1 3.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 T3SSipB PF16535.5 GBG61497.1 - 0.23 11.9 0.4 40 4.6 0.0 2.5 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF1678 PF07913.11 GBG61497.1 - 1.3 8.7 4.0 1.6 8.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1678) EcoEI_R_C PF08463.10 GBG61497.1 - 2.5 8.2 7.4 18 5.4 0.0 3.7 5 0 0 5 5 5 0 EcoEI R protein C-terminal SF3b1 PF08920.10 GBG61498.1 - 7.4e-45 152.3 29.4 1.1e-43 148.5 6.3 4.0 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.22 GBG61498.1 - 7.3e-11 41.4 2.9 0.027 14.7 0.0 8.2 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 GBG61498.1 - 3.8e-10 40.0 8.7 0.11 12.8 0.0 7.3 4 2 2 7 7 7 4 HEAT repeats HEAT_EZ PF13513.6 GBG61498.1 - 9.3e-08 32.4 1.3 0.27 11.8 0.0 5.9 6 1 1 7 7 7 2 HEAT-like repeat Cnd1 PF12717.7 GBG61498.1 - 2e-06 27.9 5.3 0.0047 17.0 0.0 5.1 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 GBG61498.1 - 0.00057 20.0 0.6 0.049 13.8 0.0 3.4 1 1 3 4 4 4 1 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 GBG61498.1 - 0.011 16.3 0.2 1.1 9.9 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 GBG61498.1 - 0.084 12.0 1.4 18 4.3 0.0 3.2 3 0 0 3 3 3 0 Dopey, N-terminal WD40 PF00400.32 GBG61499.1 - 8.7e-13 48.5 0.2 0.057 14.3 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG61499.1 - 1.2e-07 31.9 0.0 7.8 6.9 0.0 5.5 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain DUF1091 PF06477.13 GBG61500.1 - 0.015 15.8 0.2 0.043 14.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) BDV_P10 PF06515.11 GBG61501.1 - 0.003 17.6 8.7 0.0039 17.2 5.2 2.4 1 1 1 2 2 2 1 Borna disease virus P10 protein RT_RNaseH PF17917.1 GBG61502.1 - 2.3e-18 66.4 0.0 5.4e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61502.1 - 4.3e-16 58.8 0.0 9.2e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SOG2 PF10428.9 GBG61502.1 - 7.8 5.6 5.8 17 4.5 5.8 1.5 1 1 0 1 1 1 0 RAM signalling pathway protein p450 PF00067.22 GBG61503.1 - 1.6e-89 300.8 0.0 2.2e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.26 GBG61504.1 - 3.5e-36 124.5 0.9 6.6e-36 123.6 0.9 1.4 1 1 0 1 1 1 1 Proteasome subunit DUF1071 PF06378.11 GBG61504.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Ribosomal_S9 PF00380.19 GBG61505.1 - 9.8e-47 158.4 0.3 9.8e-47 158.4 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Autoind_bind PF03472.15 GBG61505.1 - 0.11 12.0 0.5 0.22 11.0 0.5 1.4 1 0 0 1 1 1 0 Autoinducer binding domain HD_3 PF13023.6 GBG61506.1 - 6.5e-47 159.5 0.1 9.3e-47 159.0 0.1 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 GBG61506.1 - 4.8e-13 49.3 0.0 7.7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 GBG61506.1 - 8.1e-06 26.1 0.3 1.9e-05 24.9 0.3 1.7 1 1 0 1 1 1 1 HD domain Trigger_N PF05697.13 GBG61507.1 - 2.3e-20 73.3 0.1 2.3e-20 73.3 0.1 2.3 2 1 0 2 2 2 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 GBG61507.1 - 3.5e-15 56.4 12.2 5.7e-15 55.7 12.2 1.4 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 GBG61507.1 - 0.0064 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Phage_holin_6_1 PF09682.10 GBG61507.1 - 0.048 14.1 1.9 0.13 12.7 1.9 1.8 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) dsDNA_bind PF01984.20 GBG61507.1 - 0.11 12.7 3.9 0.25 11.6 3.9 1.5 1 0 0 1 1 1 0 Double-stranded DNA-binding domain DUF445 PF04286.12 GBG61507.1 - 0.17 11.6 3.7 0.32 10.7 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Phage_int_SAM_6 PF18644.1 GBG61507.1 - 0.18 11.9 0.1 2.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Phage integrase SAM-like domain SurA_N_3 PF13624.6 GBG61507.1 - 0.5 10.1 4.9 14 5.4 4.6 2.6 1 1 0 1 1 1 0 SurA N-terminal domain FYDLN_acid PF09538.10 GBG61508.1 - 0.014 16.0 19.0 0.014 16.0 19.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Cellulose_synt PF03552.14 GBG61508.1 - 0.4 9.1 7.8 0.63 8.5 7.8 1.2 1 0 0 1 1 1 0 Cellulose synthase Hid1 PF12722.7 GBG61508.1 - 6.3 4.8 13.9 7.4 4.6 13.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Polo_box_3 PF18544.1 GBG61511.1 - 0.12 13.0 0.1 0.28 11.8 0.1 1.7 1 0 0 1 1 1 0 Polo box domain AP1AR PF15745.5 GBG61512.1 - 0.74 9.4 13.2 0.39 10.3 9.1 2.1 2 0 0 2 2 2 0 AP-1 complex-associated regulatory protein Oxidored_molyb PF00174.19 GBG61513.1 - 3.5e-59 199.3 0.0 5.7e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GBG61513.1 - 3.8e-38 130.6 0.2 6.5e-38 129.9 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain zf-CCHC PF00098.23 GBG61516.1 - 8.9e-05 22.4 3.2 8.9e-05 22.4 3.2 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG61516.1 - 0.0014 18.4 4.6 0.0014 18.4 4.6 2.1 2 0 0 2 2 2 1 Zinc knuckle Polo_box_3 PF18544.1 GBG61518.1 - 0.12 13.0 0.1 0.28 11.8 0.1 1.7 1 0 0 1 1 1 0 Polo box domain EMG1 PF03587.14 GBG61519.1 - 3.6e-15 56.1 0.0 4.6e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase polyprenyl_synt PF00348.17 GBG61520.1 - 1.5e-72 243.8 0.0 1.9e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ribosomal_S8 PF00410.19 GBG61521.1 - 1.2e-21 76.9 0.0 1.8e-21 76.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 RT_RNaseH PF17917.1 GBG61522.1 - 1.4e-21 76.7 0.0 3.5e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61522.1 - 2.6e-19 69.1 0.0 7.4e-19 67.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61522.1 - 1.2e-17 64.1 0.1 4.4e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61522.1 - 2.6e-07 30.5 0.0 6.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61522.1 - 4.4e-05 24.0 0.0 0.00012 22.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61522.1 - 0.00062 20.3 0.0 0.0016 19.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG61522.1 - 0.0042 17.3 0.5 0.063 13.5 0.0 3.0 3 0 0 3 3 2 1 Retrotransposon gag protein SlyX PF04102.12 GBG61522.1 - 0.0078 16.8 2.0 0.0078 16.8 2.0 3.7 4 0 0 4 4 3 1 SlyX NPV_P10 PF05531.12 GBG61522.1 - 0.044 14.2 3.8 11 6.5 0.0 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 GBG61522.1 - 0.063 13.4 2.3 6.1 7.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) BLOC1_2 PF10046.9 GBG61522.1 - 0.12 12.7 4.4 0.33 11.3 0.5 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DDRGK PF09756.9 GBG61522.1 - 0.35 10.4 6.6 0.69 9.5 6.6 1.4 1 0 0 1 1 1 0 DDRGK domain Pkinase PF00069.25 GBG61523.1 - 9.8e-50 169.4 0.0 1.4e-49 168.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61523.1 - 3.8e-16 59.2 0.0 5.8e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RT_RNaseH_2 PF17919.1 GBG61524.1 - 9.3e-23 80.2 0.0 1.7e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61524.1 - 2.2e-10 40.7 0.0 4.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61524.1 - 3.4e-08 33.3 0.1 5e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UvrD-helicase PF00580.21 GBG61525.1 - 4e-56 190.8 9.8 5.8e-55 187.0 9.8 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain RT_RNaseH_2 PF17919.1 GBG61525.1 - 5.8e-53 177.1 0.0 9.4e-30 102.6 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61525.1 - 4.4e-48 163.7 2.8 1.9e-36 125.6 0.0 3.3 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61525.1 - 7.8e-45 151.5 0.0 3.8e-29 101.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase UvrD_C PF13361.6 GBG61525.1 - 3.2e-32 112.3 9.1 1.7e-21 77.0 0.0 3.4 4 0 0 4 4 4 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 GBG61525.1 - 8.1e-27 94.3 0.0 7e-26 91.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain Integrase_H2C2 PF17921.1 GBG61525.1 - 9.8e-19 67.2 0.5 9.8e-19 67.2 0.5 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain AAA_30 PF13604.6 GBG61525.1 - 4.1e-06 26.6 7.9 0.00043 20.1 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_11 PF13086.6 GBG61525.1 - 0.00052 19.9 1.0 0.00052 19.9 1.0 3.9 4 0 0 4 4 4 1 AAA domain rve PF00665.26 GBG61525.1 - 0.00057 20.1 0.0 0.0018 18.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61525.1 - 0.0017 18.5 0.1 0.0062 16.7 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG61525.1 - 0.0019 18.1 0.1 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain UvrD_C_2 PF13538.6 GBG61525.1 - 0.0073 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Phage_integrase PF00589.22 GBG61526.1 - 0.002 17.9 0.0 0.0029 17.4 0.0 1.4 1 1 0 1 1 1 1 Phage integrase family DUF563 PF04577.14 GBG61527.1 - 1e-19 71.5 0.0 1.6e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) APC1_C PF18122.1 GBG61528.1 - 0.021 14.8 0.2 0.028 14.4 0.2 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain IBN_N PF03810.19 GBG61529.1 - 3.5e-12 46.1 0.0 1.4e-11 44.1 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 GBG61529.1 - 1.2e-05 25.7 3.1 5.5 7.6 0.2 5.9 4 0 0 4 4 4 3 HEAT-like repeat Xpo1 PF08389.12 GBG61529.1 - 0.00017 21.7 0.5 0.068 13.2 0.0 3.1 3 0 0 3 3 3 2 Exportin 1-like protein HEAT PF02985.22 GBG61529.1 - 0.11 12.8 6.7 5.5 7.5 0.1 5.9 7 0 0 7 7 7 0 HEAT repeat DUF659 PF04937.15 GBG61530.1 - 6e-08 32.7 0.0 9.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) LCM PF04072.14 GBG61531.1 - 2.1e-35 122.4 2.5 1.5e-28 100.0 0.1 2.4 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase DDE_Tnp_IS1595 PF12762.7 GBG61531.1 - 0.031 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 ISXO2-like transposase domain Chorion_S16 PF05836.12 GBG61531.1 - 0.097 12.9 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Chorion protein S16 Phycoerythr_ab PF02972.14 GBG61531.1 - 0.25 11.2 1.3 0.83 9.5 1.3 1.9 1 0 0 1 1 1 0 Phycoerythrin, alpha/beta chain DB PF01682.19 GBG61532.1 - 0.18 12.2 8.4 0.72 10.2 0.3 2.2 2 0 0 2 2 2 0 DB module GCK PF07802.11 GBG61532.1 - 0.86 10.1 7.1 4.5 7.8 0.3 2.2 2 0 0 2 2 2 0 GCK domain Cmc1 PF08583.10 GBG61532.1 - 1.9 8.5 9.0 3.8 7.6 0.6 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_4 PF14295.6 GBG61532.1 - 5.8 6.9 9.6 15 5.6 2.4 2.7 2 1 0 2 2 2 0 PAN domain CDC27 PF09507.10 GBG61533.1 - 2.1 7.7 40.8 2.9 7.2 40.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Myb_DNA-bind_4 PF13837.6 GBG61535.1 - 3.9e-06 27.1 0.4 5.4e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG61535.1 - 0.01 15.9 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG61536.1 - 1.5e-29 102.7 0.0 3e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61536.1 - 1.3e-10 41.3 0.0 3.4e-10 39.9 0.0 1.7 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61536.1 - 0.016 14.9 0.0 1.9 8.1 0.2 2.4 2 0 0 2 2 2 0 Transposase DDE domain zf-CCHC PF00098.23 GBG61538.1 - 4.1e-06 26.6 3.4 8e-06 25.7 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF295 PF03478.18 GBG61538.1 - 0.041 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF295) Sec6 PF06046.13 GBG61538.1 - 1.5 7.1 8.4 2.3 6.5 8.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec6 Patatin PF01734.22 GBG61539.1 - 1.5e-07 31.8 0.3 5.7e-07 29.9 0.3 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Peptidase_S8 PF00082.22 GBG61539.1 - 0.053 12.8 1.8 0.093 12.0 1.8 1.3 1 0 0 1 1 1 0 Subtilase family EF-hand_13 PF17958.1 GBG61541.1 - 1.6e-38 130.4 0.1 7.3e-37 125.1 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 GBG61541.1 - 1e-23 83.6 12.2 1.8e-18 66.8 1.6 4.9 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 GBG61541.1 - 4.1e-11 41.6 3.4 0.01 15.3 0.0 6.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 GBG61541.1 - 5.3e-10 38.4 4.9 0.005 16.7 0.0 5.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 GBG61541.1 - 7.3e-08 32.1 5.2 0.058 13.2 0.1 4.7 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG61541.1 - 2.5e-06 26.7 1.9 0.0046 16.4 0.0 4.5 5 0 0 5 5 5 1 EF hand Sulfotransfer_3 PF13469.6 GBG61541.1 - 0.043 14.2 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family DUF4187 PF13821.6 GBG61541.1 - 0.096 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RT_RNaseH_2 PF17919.1 GBG61542.1 - 2.4e-27 94.9 0.0 8.3e-27 93.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61542.1 - 1.5e-26 93.3 0.1 2.2e-26 92.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61542.1 - 3.7e-25 88.2 0.0 1.1e-24 86.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase YL1 PF05764.13 GBG61542.1 - 0.047 13.8 5.7 0.077 13.1 5.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 GBG61542.1 - 7.6 4.7 7.8 11 4.2 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG61543.1 - 1.8e-09 37.6 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61543.1 - 0.0036 17.1 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RR_TM4-6 PF06459.12 GBG61544.1 - 2.6 7.8 4.9 4.8 6.9 4.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec63 PF02889.16 GBG61545.1 - 4.5e-19 68.6 0.0 6.9e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 GBG61545.1 - 2e-17 63.1 3.7 4.9e-17 61.8 3.7 1.7 1 0 0 1 1 1 1 DnaJ domain HHH_5 PF14520.6 GBG61545.1 - 0.025 15.2 0.0 0.061 13.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain BUD22 PF09073.10 GBG61545.1 - 0.19 11.0 16.7 0.31 10.3 16.7 1.3 1 0 0 1 1 1 0 BUD22 WD40 PF00400.32 GBG61546.1 - 2.4e-10 40.8 8.5 0.24 12.3 0.2 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF2457 PF10446.9 GBG61546.1 - 0.00015 21.0 4.9 0.00015 21.0 4.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) DUF3391 PF11871.8 GBG61546.1 - 0.057 14.0 3.8 0.12 12.9 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) CDC45 PF02724.14 GBG61546.1 - 0.99 7.6 18.1 0.0048 15.3 5.5 2.1 2 0 0 2 2 2 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG61546.1 - 5.7 5.4 31.5 0.017 13.7 9.3 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FYDLN_acid PF09538.10 GBG61546.1 - 6.7 7.4 23.8 8.9 7.0 4.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 GBG61546.1 - 8.2 4.5 26.3 0.16 10.2 12.7 2.0 2 0 0 2 2 2 0 Nop14-like family DUF4484 PF14831.6 GBG61546.1 - 8.5 6.4 12.0 19 5.2 6.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) CPSF100_C PF13299.6 GBG61546.1 - 8.9 6.5 11.9 1.1 9.5 6.7 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIIAH PF12685.7 GBG61548.1 - 0.065 13.1 9.4 0.088 12.6 9.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein PPP4R2 PF09184.11 GBG61548.1 - 0.079 12.5 15.8 0.12 12.0 15.8 1.3 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 GBG61548.1 - 0.14 11.5 24.7 0.18 11.2 24.7 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG61548.1 - 0.15 11.4 24.0 0.21 10.9 24.0 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GBG61548.1 - 0.34 10.6 19.8 0.48 10.1 19.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG61548.1 - 0.62 8.2 25.7 0.77 7.9 25.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG61548.1 - 0.78 9.1 17.9 1.1 8.6 17.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 GBG61548.1 - 0.84 7.9 16.2 1.1 7.5 16.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GBG61548.1 - 2.4 6.8 6.2 2.4 6.9 6.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Astro_capsid_p PF12226.8 GBG61548.1 - 2.4 7.2 15.9 3.3 6.8 15.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF913 PF06025.12 GBG61548.1 - 3.4 6.5 5.1 4.5 6.1 5.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LAP1C PF05609.12 GBG61548.1 - 4.8 6.2 12.0 6.2 5.8 12.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DHHC PF01529.20 GBG61551.1 - 0.0014 18.8 0.1 0.0024 18.0 0.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase SH3_15 PF18346.1 GBG61552.1 - 2.2e-36 124.0 10.4 6.4e-09 36.0 0.0 6.0 4 2 0 4 4 4 4 Mind bomb SH3 repeat domain Pkinase PF00069.25 GBG61552.1 - 9.9e-25 87.4 0.0 1.7e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61552.1 - 1.7e-20 73.4 0.0 3.2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2457 PF10446.9 GBG61552.1 - 6.1 5.9 8.0 13 4.8 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-RING_UBOX PF13445.6 GBG61553.1 - 2.1e-08 34.1 7.9 3.1e-08 33.5 7.9 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG61553.1 - 1e-07 31.8 6.1 1.5e-07 31.3 6.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GBG61553.1 - 2.7e-06 27.6 5.8 3.9e-06 27.1 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG61553.1 - 1.9e-05 24.4 6.7 3.2e-05 23.7 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG61553.1 - 0.00019 21.2 7.8 0.00023 20.9 0.8 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GBG61553.1 - 0.00038 20.3 7.2 0.0011 18.8 7.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Pkinase_Tyr PF07714.17 GBG61553.1 - 0.00042 19.7 0.0 0.00057 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C3HC4_2 PF13923.6 GBG61553.1 - 0.00075 19.3 10.1 0.0028 17.5 9.8 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG61553.1 - 0.0014 18.9 4.5 0.0024 18.1 4.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 GBG61553.1 - 0.0081 16.0 5.0 0.016 15.1 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 GBG61553.1 - 0.012 15.7 0.9 0.02 15.0 0.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.6 GBG61553.1 - 0.033 14.0 9.6 0.24 11.2 9.6 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 GBG61553.1 - 0.035 13.9 1.3 0.073 12.8 1.4 1.6 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 GBG61553.1 - 0.043 13.7 1.2 0.076 12.9 1.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Pkinase PF00069.25 GBG61553.1 - 0.048 13.0 0.1 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 Protein kinase domain zf-C3HC4_4 PF15227.6 GBG61553.1 - 0.069 13.3 6.9 0.24 11.6 6.9 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FYDLN_acid PF09538.10 GBG61553.1 - 0.11 13.2 0.9 0.15 12.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-ANAPC11 PF12861.7 GBG61553.1 - 0.16 12.1 2.2 0.27 11.3 2.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 GBG61553.1 - 0.18 11.9 3.3 0.31 11.2 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) IBR PF01485.21 GBG61553.1 - 0.3 11.3 5.6 0.51 10.6 5.5 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Pkinase_Tyr PF07714.17 GBG61554.1 - 4.6e-29 101.5 0.0 9.1e-24 84.1 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG61554.1 - 3.5e-28 98.7 0.0 1e-25 90.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain SH3_15 PF18346.1 GBG61554.1 - 4.7e-21 74.9 1.1 8.6e-08 32.4 0.0 4.2 2 2 0 2 2 2 2 Mind bomb SH3 repeat domain tRNA_anti-codon PF01336.25 GBG61554.1 - 0.019 15.0 0.0 0.34 10.9 0.0 2.3 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain Kinase-like PF14531.6 GBG61554.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RT_RNaseH_2 PF17919.1 GBG61556.1 - 3.6e-32 110.3 0.0 8.4e-32 109.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61556.1 - 4.8e-29 100.7 0.1 1.1e-28 99.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG61556.1 - 0.0069 16.1 0.3 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) rve PF00665.26 GBG61556.1 - 0.024 14.8 0.1 0.069 13.3 0.1 1.8 1 0 0 1 1 1 0 Integrase core domain DUF659 PF04937.15 GBG61558.1 - 1.7e-27 96.2 0.1 2.4e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61558.1 - 0.00022 20.9 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ZapB PF06005.12 GBG61560.1 - 0.023 15.1 4.9 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 Cell division protein ZapB KIND PF16474.5 GBG61560.1 - 5.1 6.9 12.6 0.21 11.5 2.3 2.5 2 1 0 2 2 2 0 Kinase non-catalytic C-lobe domain Helicase_C PF00271.31 GBG61561.1 - 1.6e-32 112.2 0.0 3.3e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GBG61561.1 - 3.8e-32 111.5 0.1 9.9e-18 64.5 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 GBG61561.1 - 0.0086 16.1 0.0 0.023 14.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 GBG61561.1 - 0.19 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Dimer_Tnp_hAT PF05699.14 GBG61562.1 - 0.012 15.4 0.1 0.023 14.5 0.1 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Rod-binding PF10135.9 GBG61562.1 - 0.19 12.3 0.6 6.1 7.5 0.6 2.8 2 0 0 2 2 2 0 Rod binding protein zf-FCS PF06467.14 GBG61562.1 - 0.58 10.1 1.9 1.2 9.1 1.9 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Ist1 PF03398.14 GBG61563.1 - 5e-22 78.6 0.2 5.8e-22 78.4 0.2 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Nucleotid_trans PF03407.16 GBG61565.1 - 1.7e-31 109.9 0.0 2.6e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase BIRC6 PF12356.8 GBG61565.1 - 0.27 10.7 0.9 0.53 9.7 0.0 1.8 3 0 0 3 3 3 0 Baculoviral IAP repeat-containing protein 6 RVT_1 PF00078.27 GBG61566.1 - 1.6e-28 99.7 0.1 2.8e-28 99.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG61566.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG61569.1 - 8.7e-24 84.3 0.1 1.1e-23 83.9 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L1 PF00687.21 GBG61570.1 - 5.1e-51 173.3 0.3 5.1e-51 173.3 0.3 1.4 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family ALMT PF11744.8 GBG61571.1 - 1.2 7.8 6.4 2.1 7.1 5.6 1.7 1 1 0 1 1 1 0 Aluminium activated malate transporter CBS PF00571.28 GBG61572.1 - 1.8e-25 89.1 4.8 4.9e-14 52.5 0.5 2.2 2 0 0 2 2 2 2 CBS domain CP12 PF02672.15 GBG61574.1 - 1.2e-23 83.7 5.4 1.6e-23 83.2 5.4 1.2 1 0 0 1 1 1 1 CP12 domain LUC7 PF03194.15 GBG61574.1 - 0.028 14.1 0.1 0.032 13.9 0.1 1.1 1 0 0 1 1 1 0 LUC7 N_terminus GlutR_N PF05201.15 GBG61575.1 - 1.8e-42 144.5 0.0 3.4e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 GBG61575.1 - 4.4e-40 136.9 0.0 8.7e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 GBG61575.1 - 8.5e-27 93.4 0.1 1.7e-26 92.5 0.1 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 GBG61575.1 - 8.4e-06 26.3 1.7 7e-05 23.3 0.0 3.0 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 GBG61575.1 - 0.0016 18.7 0.0 0.0037 17.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 GBG61575.1 - 0.0038 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RNaseH_like PF04308.12 GBG61575.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease H-like NAD_binding_7 PF13241.6 GBG61575.1 - 0.14 12.6 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding AhpC-TSA_2 PF13911.6 GBG61577.1 - 3.1e-16 59.5 0.0 4.9e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 GBG61577.1 - 0.00041 20.3 0.0 0.00078 19.4 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Phage_GPA PF05840.13 GBG61578.1 - 0.038 13.1 2.2 0.057 12.5 2.2 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) HBB PF06777.11 GBG61578.1 - 0.22 11.2 2.0 0.34 10.6 2.0 1.2 1 0 0 1 1 1 0 Helical and beta-bridge domain MIF4G_like_2 PF09090.11 GBG61578.1 - 0.22 11.0 6.3 0.32 10.4 6.3 1.1 1 0 0 1 1 1 0 MIF4G like DUF5094 PF17015.5 GBG61578.1 - 0.31 11.1 2.3 0.47 10.5 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) AAA_13 PF13166.6 GBG61578.1 - 2.7 6.5 5.3 3.5 6.1 5.3 1.1 1 0 0 1 1 1 0 AAA domain Cyclin_N PF00134.23 GBG61580.1 - 1e-25 89.9 0.0 3.3e-25 88.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GBG61580.1 - 4.2e-25 88.2 0.1 7.4e-25 87.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pkinase PF00069.25 GBG61581.1 - 5.9e-19 68.4 0.0 1.4e-18 67.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG61581.1 - 5.6e-09 35.7 0.0 2.1e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase RT_RNaseH_2 PF17919.1 GBG61582.1 - 5.8e-26 90.4 0.0 9.5e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61582.1 - 6.6e-24 84.2 0.0 1.2e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61582.1 - 5.3e-10 39.2 0.0 8.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG61582.1 - 1.9e-07 30.8 1.1 4.2e-07 29.8 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG61582.1 - 0.0037 17.0 1.3 0.006 16.4 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle SDA1 PF05285.12 GBG61582.1 - 0.14 11.6 8.4 0.19 11.1 8.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG61582.1 - 0.79 7.9 9.8 1 7.5 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG61582.1 - 1 9.6 13.3 1.9 8.8 13.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG61582.1 - 2.1 6.5 10.1 2.9 6.1 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TAFII55_N PF04658.13 GBG61583.1 - 4.2e-30 104.6 0.0 1.3e-28 99.7 0.0 2.2 1 1 0 1 1 1 1 TAFII55 protein conserved region S1 PF00575.23 GBG61584.1 - 1.5e-76 252.8 49.5 4.8e-13 49.3 1.2 15.3 15 1 0 15 15 15 13 S1 RNA binding domain Suf PF05843.14 GBG61584.1 - 2.7e-12 47.3 7.9 6.1e-07 29.7 0.0 4.0 1 1 3 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 GBG61584.1 - 0.00015 22.2 0.0 0.91 10.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 GBG61584.1 - 0.0081 15.3 3.0 0.89 8.6 0.0 3.4 1 1 1 4 4 4 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 GBG61584.1 - 0.016 16.0 0.0 4.9 8.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat S1_2 PF13509.6 GBG61584.1 - 3.3 7.8 4.7 23 5.1 0.0 4.8 5 0 0 5 5 5 0 S1 domain RT_RNaseH_2 PF17919.1 GBG61585.1 - 4.7e-26 90.7 0.0 1e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61585.1 - 2.3e-24 85.7 0.0 4.2e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61585.1 - 2.2e-18 66.1 0.7 2.7e-17 62.6 0.4 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG61585.1 - 8.4e-10 38.5 0.1 1.4e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PX PF00787.24 GBG61586.1 - 8.9e-15 54.7 0.0 2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 PX domain GAS PF13851.6 GBG61586.1 - 1.4 8.2 37.7 0.05 13.0 20.0 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2470 PF10615.9 GBG61587.1 - 0.0011 19.5 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF5461 PF17545.2 GBG61587.1 - 0.17 12.2 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5461) Ribo_biogen_C PF04034.13 GBG61588.1 - 3.5e-51 172.2 0.0 6.2e-51 171.4 0.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal POPLD PF08170.12 GBG61588.1 - 5.7e-17 61.8 0.1 5.7e-17 61.8 0.1 2.7 2 0 0 2 2 2 1 POPLD (NUC188) domain RLI PF04068.15 GBG61588.1 - 1.3e-14 53.7 0.1 1.2e-13 50.6 0.1 2.5 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI POP1 PF06978.11 GBG61588.1 - 3.5e-14 53.3 13.0 1.8e-13 50.9 13.0 2.2 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 EamA PF00892.20 GBG61589.1 - 1.1e-46 158.4 29.6 2.7e-23 82.7 9.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family MOSC_N PF03476.16 GBG61589.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain MCU PF04678.13 GBG61590.1 - 0.14 12.2 1.0 0.18 11.9 1.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter eRF1_2 PF03464.15 GBG61592.1 - 5.8e-42 143.1 0.0 9.9e-42 142.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GBG61592.1 - 4.6e-37 127.0 0.2 8.4e-37 126.1 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 GBG61592.1 - 5.5e-19 68.4 0.0 8.9e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 GBG61592.1 - 2.4e-07 31.1 0.0 3.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 GBG61592.1 - 5.3e-07 30.0 0.0 1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ribosomal_L7Ae PF01248.26 GBG61592.1 - 0.17 11.6 0.0 0.48 10.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UPF0160 PF03690.13 GBG61593.1 - 1e-130 436.1 0.0 1.3e-130 435.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Cullin_binding PF03556.15 GBG61594.1 - 3.4e-38 130.8 0.9 5.5e-38 130.1 0.9 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 GBG61594.1 - 5.3e-11 42.2 0.0 2.8e-10 39.8 0.0 2.3 2 0 0 2 2 2 1 UBA-like domain UBA PF00627.31 GBG61594.1 - 0.0065 16.4 1.3 0.013 15.4 1.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain B3 PF02362.21 GBG61594.1 - 0.035 14.0 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 B3 DNA binding domain CRAL_TRIO_N PF03765.15 GBG61594.1 - 0.081 13.1 0.9 2.8 8.2 0.1 3.2 2 1 0 2 2 2 0 CRAL/TRIO, N-terminal domain GAD PF02938.14 GBG61594.1 - 0.16 12.2 0.0 0.47 10.7 0.0 1.8 2 0 0 2 2 2 0 GAD domain RVT_1 PF00078.27 GBG61595.1 - 1.1e-14 54.5 0.0 2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG61595.1 - 0.0025 18.1 0.1 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein SDA1 PF05285.12 GBG61595.1 - 1.8 7.9 21.4 2.5 7.4 21.4 1.1 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 GBG61595.1 - 2.3 7.5 16.9 3.3 7.0 16.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 GBG61595.1 - 7.9 4.5 18.9 11 4.1 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family SBF PF01758.16 GBG61596.1 - 1.8e-34 119.1 14.5 2.7e-34 118.5 14.5 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family RT_RNaseH_2 PF17919.1 GBG61596.1 - 1.4e-31 108.4 0.0 2.7e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61596.1 - 4.2e-28 97.7 0.2 8e-28 96.8 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61596.1 - 1e-19 71.0 0.0 2.1e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG61596.1 - 4.9e-19 68.2 0.1 1.3e-18 66.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61596.1 - 3.6e-09 36.8 0.0 7.3e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain SBF_like PF13593.6 GBG61596.1 - 3.6e-07 29.8 14.5 5.6e-07 29.2 14.5 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) zf-H2C2 PF09337.10 GBG61596.1 - 0.0018 18.4 0.1 0.0075 16.5 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG61596.1 - 0.016 15.2 1.4 0.041 13.8 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle FAM183 PF14886.6 GBG61597.1 - 0.0078 16.9 0.0 0.016 15.9 0.0 1.5 1 0 0 1 1 1 1 FAM183A and FAM183B related DEK_C PF08766.11 GBG61598.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain BUD22 PF09073.10 GBG61598.1 - 0.0041 16.5 14.1 0.007 15.8 14.1 1.3 1 0 0 1 1 1 1 BUD22 RPN2_C PF18004.1 GBG61598.1 - 0.043 13.7 13.4 0.44 10.5 12.5 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 GBG61598.1 - 0.047 12.0 14.2 0.069 11.4 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Usp PF00582.26 GBG61598.1 - 0.088 13.3 5.2 0.17 12.4 5.2 1.5 1 0 0 1 1 1 0 Universal stress protein family NPR3 PF03666.13 GBG61598.1 - 0.15 10.9 5.1 1.1 7.9 6.5 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 MADF_DNA_bdg PF10545.9 GBG61598.1 - 0.16 12.3 0.5 0.57 10.5 0.1 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SpoIIIAH PF12685.7 GBG61598.1 - 0.24 11.2 7.8 0.39 10.5 7.8 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein RNA_pol_3_Rpc31 PF11705.8 GBG61598.1 - 1 9.5 28.8 2.5 8.3 28.8 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 GBG61598.1 - 1.3 7.2 25.4 1.9 6.6 25.4 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG61598.1 - 1.8 8.9 21.8 3.7 7.8 21.8 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Mpp10 PF04006.12 GBG61598.1 - 6.4 5.1 24.0 9.1 4.6 24.0 1.1 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 GBG61598.1 - 8.5 6.1 13.7 15 5.3 13.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 GBG61598.1 - 8.7 5.8 24.6 14 5.2 24.6 1.3 1 0 0 1 1 1 0 PPP4R2 Zip PF02535.22 GBG61598.1 - 9.5 5.3 6.7 15 4.7 6.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-CCHC PF00098.23 GBG61600.1 - 1.5e-05 24.9 3.4 3e-05 23.9 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle LAP1C PF05609.12 GBG61600.1 - 0.0051 16.0 5.4 0.0082 15.3 5.4 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) zf-CCHC_2 PF13696.6 GBG61600.1 - 0.032 14.1 5.0 0.061 13.2 5.0 1.5 1 0 0 1 1 1 0 Zinc knuckle TMEM154 PF15102.6 GBG61600.1 - 0.29 11.0 13.9 0.4 10.6 0.0 2.8 2 1 1 3 3 3 0 TMEM154 protein family DUF1908 PF08926.11 GBG61600.1 - 0.31 10.1 1.6 1.3 8.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) DUF2615 PF11027.8 GBG61600.1 - 4.2 7.5 12.2 0.77 9.9 2.9 3.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2615) RVT_1 PF00078.27 GBG61601.1 - 2e-29 102.7 0.1 3.5e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61601.1 - 3.3e-16 59.1 0.0 1e-15 57.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG61601.1 - 5.6e-09 35.9 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61601.1 - 6.2e-08 33.2 0.0 1.6e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG61601.1 - 3.3e-07 30.6 0.0 1e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG61601.1 - 3.8e-06 27.4 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61601.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG61601.1 - 0.0031 18.1 0.3 0.0031 18.1 0.3 3.3 4 0 0 4 4 4 1 SlyX Retrotrans_gag PF03732.17 GBG61601.1 - 0.05 13.9 0.0 0.3 11.4 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein PTS_IIA PF02255.16 GBG61601.1 - 0.81 9.8 5.9 4.3 7.5 4.0 2.8 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit RT_RNaseH_2 PF17919.1 GBG61602.1 - 1.7e-26 92.2 0.0 4.5e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61602.1 - 7.5e-23 80.8 0.0 1.8e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61602.1 - 1.1e-18 67.6 0.1 2.1e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG61602.1 - 0.32 9.2 20.8 0.51 8.6 20.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 GBG61602.1 - 1.6 7.8 18.6 3.7 6.6 18.6 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 GBG61602.1 - 2.9 6.0 30.9 4.8 5.3 30.9 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG61602.1 - 3.7 6.0 32.8 0.02 13.5 23.8 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PI3K_1B_p101 PF10486.9 GBG61602.1 - 7 4.3 7.0 11 3.6 7.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TAFII28 PF04719.14 GBG61603.1 - 6.6e-32 109.4 0.0 1e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region NPL PF17800.1 GBG61604.1 - 1.3e-07 32.2 0.0 1.3e-07 32.2 0.0 5.5 5 3 0 5 5 5 1 Nucleoplasmin-like domain Peptidase_S10 PF00450.22 GBG61605.1 - 4.3e-133 444.8 0.0 2.2e-91 307.4 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase Plasmodium_Vir PF05795.11 GBG61605.1 - 0.14 11.5 0.5 0.25 10.7 0.5 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RT_RNaseH_2 PF17919.1 GBG61606.1 - 1.8e-27 95.3 0.0 3.3e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61606.1 - 7.8e-25 87.2 0.0 1.4e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61606.1 - 2.7e-05 23.8 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG61607.1 - 1.7e-26 93.1 0.1 2.6e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAD_porph PF04371.15 GBG61608.1 - 1.4e-121 405.7 0.0 1.6e-121 405.5 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 GBG61608.1 - 0.23 10.5 0.1 0.64 9.1 0.0 1.7 2 0 0 2 2 2 0 Amidinotransferase zf-RanBP PF00641.18 GBG61609.1 - 9.4e-13 47.2 15.3 3.2e-07 29.6 4.7 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 GBG61609.1 - 2.3 8.3 10.4 5.7 7.0 1.4 2.2 2 0 0 2 2 2 0 Double zinc ribbon zf-RanBP PF00641.18 GBG61610.1 - 1.8e-13 49.5 14.4 6.4e-08 31.8 3.8 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 GBG61610.1 - 0.24 11.5 10.7 1.2 9.2 2.3 2.2 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 GBG61610.1 - 0.25 11.4 6.5 0.31 11.0 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbons zinc-ribbon_6 PF10005.9 GBG61610.1 - 0.55 10.9 6.4 1.7 9.4 0.8 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Retrotrans_gag PF03732.17 GBG61611.1 - 0.008 16.4 0.1 0.022 15.0 0.1 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG61611.1 - 0.26 11.1 0.9 0.39 10.6 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4708 PF15813.5 GBG61612.1 - 0.07 12.3 0.2 0.1 11.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) gag-asp_proteas PF13975.6 GBG61614.1 - 1.6e-09 38.2 0.0 3.2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61614.1 - 5.1e-07 30.2 0.0 9.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG61614.1 - 5.7e-05 23.4 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG61614.1 - 8.8e-05 22.3 0.4 0.00017 21.4 0.4 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG61615.1 - 7.2e-33 112.6 0.1 1.5e-32 111.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61615.1 - 1.8e-29 102.1 0.2 5.1e-29 100.6 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61615.1 - 6.9e-05 23.0 0.0 0.00026 21.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG61615.1 - 0.036 13.7 1.0 0.079 12.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) FAM199X PF15814.5 GBG61615.1 - 5.2 6.0 6.9 9.4 5.2 6.9 1.3 1 0 0 1 1 1 0 Protein family FAM199X RT_RNaseH_2 PF17919.1 GBG61616.1 - 1.1e-24 86.4 0.0 2.5e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61616.1 - 2.4e-23 82.4 0.0 2.4e-22 79.2 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61616.1 - 2.7e-16 59.9 0.0 6.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG61616.1 - 2.6e-13 49.8 0.0 7.9e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG61616.1 - 0.00016 21.2 0.0 0.00056 19.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG61616.1 - 0.014 15.1 0.0 0.046 13.5 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Chromo PF00385.24 GBG61617.1 - 0.009 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 GBG61618.1 - 3e-05 23.9 3.4 3e-05 23.9 3.4 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG61618.1 - 0.0038 16.9 1.4 0.0092 15.7 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Trehalase PF01204.18 GBG61618.1 - 0.052 12.4 0.5 0.097 11.5 0.5 1.4 1 0 0 1 1 1 0 Trehalase zf-CCHC_2 PF13696.6 GBG61618.1 - 0.2 11.5 0.6 0.45 10.4 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF5320 PF17253.2 GBG61618.1 - 0.26 12.4 0.2 0.26 12.4 0.2 3.7 4 1 1 5 5 5 0 Family of unknown function (DUF5320) RVT_1 PF00078.27 GBG61620.1 - 6.4e-34 117.4 0.6 2.7e-33 115.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61620.1 - 9.4e-11 41.9 0.0 2.8e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG61620.1 - 9e-07 29.4 0.0 2.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61620.1 - 1.7e-05 25.3 0.0 4.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG61620.1 - 0.0019 17.9 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG61620.1 - 0.002 17.9 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG61620.1 - 0.0025 17.7 0.6 0.012 15.5 0.1 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG61620.1 - 0.021 15.1 0.5 4.8 7.5 0.0 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein CBS PF00571.28 GBG61621.1 - 4.2e-25 87.9 5.1 2.5e-08 34.2 0.2 4.9 4 1 1 5 5 5 4 CBS domain DUF2018 PF09442.10 GBG61621.1 - 0.032 15.2 0.0 0.24 12.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Ins134_P3_kin PF05770.11 GBG61621.1 - 0.13 11.8 0.3 7.7 6.0 0.1 2.4 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Mucin PF01456.17 GBG61622.1 - 0.0025 17.8 31.8 0.018 15.0 30.8 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF2076 PF09849.9 GBG61622.1 - 3.7 7.5 7.6 6.2 6.8 7.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex19 PF04614.12 GBG61623.1 - 2.6e-40 138.8 1.1 7.2e-40 137.3 0.1 1.8 2 0 0 2 2 2 1 Pex19 protein family PriC PF07445.12 GBG61623.1 - 0.002 18.1 1.7 0.0028 17.6 1.7 1.1 1 0 0 1 1 1 1 Primosomal replication protein priC YppG PF14179.6 GBG61623.1 - 0.021 15.5 1.8 0.97 10.2 0.5 2.3 1 1 1 2 2 2 0 YppG-like protein DUF3288 PF11691.8 GBG61623.1 - 0.062 13.3 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) Spore_IV_A PF09547.10 GBG61623.1 - 0.12 11.3 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) SH3_18 PF18354.1 GBG61626.1 - 0.22 11.6 2.6 1.1 9.3 0.3 2.3 2 0 0 2 2 2 0 CarS bacterial SH3 domain SH3_12 PF18129.1 GBG61626.1 - 0.23 11.6 8.1 0.35 11.0 1.4 2.6 2 0 0 2 2 2 0 Xrn1 SH3-like domain DPBB_1 PF03330.18 GBG61628.1 - 1.7e-11 44.2 1.6 1.8e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG61628.1 - 1.7e-10 40.8 0.0 2.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen Myb_DNA-bind_4 PF13837.6 GBG61629.1 - 7.9e-08 32.6 3.0 1.1e-07 32.1 1.6 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG61629.1 - 0.00035 20.7 0.1 0.021 15.0 0.2 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG61629.1 - 0.0021 18.3 2.1 0.012 15.9 0.7 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like LapA_dom PF06305.11 GBG61629.1 - 0.0062 16.3 0.3 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Myb_DNA-bind_5 PF13873.6 GBG61629.1 - 0.0081 16.2 0.1 0.02 14.9 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG61630.1 - 6.1e-27 94.2 0.0 8.1e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61630.1 - 5.8e-12 45.6 0.0 8.1e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61630.1 - 1.7e-05 24.6 0.1 0.0003 20.5 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain RVT_1 PF00078.27 GBG61631.1 - 6.1e-31 107.7 0.0 9.2e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61631.1 - 2.6e-30 104.4 0.0 1.4e-15 57.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61631.1 - 1.4e-19 70.3 0.0 2.9e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1995 PF09353.10 GBG61632.1 - 6.3e-21 75.3 0.0 1e-20 74.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DDE_Tnp_4 PF13359.6 GBG61634.1 - 4.1e-31 107.8 0.0 7e-30 103.8 0.0 2.5 2 1 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61634.1 - 1.9e-16 60.3 0.0 3.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61634.1 - 0.0002 21.1 0.0 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG61634.1 - 0.082 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG61635.1 - 6.3e-35 119.2 0.0 1.5e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61635.1 - 2e-32 111.6 0.0 4.5e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG61636.1 - 1.4e-07 32.1 7.5 0.00019 22.2 0.7 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG61636.1 - 0.00077 19.7 0.5 0.52 10.6 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain C2 PF00168.30 GBG61637.1 - 1.8e-33 114.9 0.0 9.9e-16 57.9 0.0 2.3 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 GBG61637.1 - 7.1e-20 71.2 0.1 1.1e-19 70.6 0.1 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Na_Ca_ex PF01699.24 GBG61639.1 - 1.8e-28 99.4 34.9 1.3e-17 64.1 11.5 3.1 3 1 0 3 3 3 2 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 GBG61640.1 - 5.2e-40 136.9 38.2 1.9e-24 86.3 10.5 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Nop14 PF04147.12 GBG61641.1 - 0.086 11.0 13.9 0.091 11.0 13.9 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG61641.1 - 0.14 11.5 17.8 0.17 11.2 17.8 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG61641.1 - 0.27 10.6 16.6 0.31 10.4 16.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG61641.1 - 0.52 8.5 13.8 0.63 8.3 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG61641.1 - 1 9.0 14.7 1.4 8.6 14.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RT_RNaseH_2 PF17919.1 GBG61642.1 - 1.4e-34 118.1 0.5 2.8e-34 117.1 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61642.1 - 1.2e-30 105.9 0.1 2.8e-30 104.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61642.1 - 3.6e-18 65.9 1.0 9.3e-17 61.3 0.4 2.3 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TOBE_2 PF08402.10 GBG61642.1 - 0.15 12.3 0.0 0.7 10.1 0.0 2.2 2 0 0 2 2 2 0 TOBE domain RVT_1 PF00078.27 GBG61643.1 - 4.7e-66 222.5 0.1 1.4e-32 113.0 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61643.1 - 3.5e-64 213.1 0.1 4.3e-31 106.9 0.0 3.4 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61643.1 - 1.3e-62 208.7 0.6 3.8e-30 104.3 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61643.1 - 2.4e-24 85.8 0.1 2.6e-15 56.7 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG61643.1 - 1.7e-17 63.2 0.6 4.6e-17 61.9 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG61643.1 - 9.6e-12 44.8 0.0 2.3e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61643.1 - 8.7e-08 32.7 0.0 4.2e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61643.1 - 4.2e-06 27.2 0.1 1.4e-05 25.6 0.0 1.9 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG61643.1 - 4.7e-05 23.2 0.5 0.0015 18.3 0.1 2.6 3 0 0 3 3 3 1 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG61643.1 - 0.012 15.3 0.1 0.32 10.6 0.1 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase rve_3 PF13683.6 GBG61643.1 - 0.014 15.1 0.4 7.6 6.4 0.0 3.3 3 0 0 3 3 2 0 Integrase core domain zf-H2C2 PF09337.10 GBG61643.1 - 0.1 12.9 0.1 0.28 11.4 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger SH3_16 PF18348.1 GBG61643.1 - 0.11 12.3 0.0 26 4.7 0.0 2.7 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain RVT_1 PF00078.27 GBG61644.1 - 8.1e-27 94.2 0.1 1.4e-26 93.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61644.1 - 1.4e-23 82.8 0.0 3.8e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61644.1 - 2.1e-19 69.8 0.0 5.9e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG61644.1 - 1.8e-06 28.1 1.2 0.0036 17.6 0.0 3.9 3 0 0 3 3 3 2 Retrotransposon gag protein RVT_1 PF00078.27 GBG61645.1 - 1.7e-26 93.1 0.0 2.9e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61645.1 - 8.7e-06 25.5 0.1 2.5e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61645.1 - 1.7e-05 25.3 0.0 4.9e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61645.1 - 2.4e-05 24.8 0.0 8.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61645.1 - 0.0076 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG61645.1 - 0.023 14.9 0.5 0.1 12.9 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Senescence_reg PF04520.13 GBG61645.1 - 0.14 13.0 1.0 0.47 11.3 1.2 1.8 2 0 0 2 2 2 0 Senescence regulator RVT_1 PF00078.27 GBG61646.1 - 8.4e-28 97.4 0.1 1.4e-27 96.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61646.1 - 2e-26 92.0 0.7 8.7e-25 86.7 0.7 2.4 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61646.1 - 1.3e-21 76.8 2.8 7.7e-20 71.1 2.8 2.4 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61646.1 - 1.3e-17 63.6 0.1 3e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF5095 PF17016.5 GBG61646.1 - 0.46 10.1 1.9 0.4 10.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) DBD_Tnp_Hermes PF10683.9 GBG61647.1 - 1.9e-07 30.7 0.0 3.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain MCR PF18509.1 GBG61647.1 - 0.14 11.7 0.2 0.14 11.7 0.2 1.7 2 0 0 2 2 2 0 Magnetochrome domain Morc6_S5 PF17942.1 GBG61648.1 - 4.4e-57 192.0 0.1 7.4e-57 191.3 0.1 1.4 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like HATPase_c_3 PF13589.6 GBG61648.1 - 9.5e-14 51.4 0.2 3.5e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GBG61648.1 - 4.6e-05 23.9 0.1 0.00018 22.0 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tubulin PF00091.25 GBG61649.1 - 2.2e-42 145.5 0.2 2.2e-42 145.5 0.2 2.3 3 0 0 3 3 3 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 GBG61649.1 - 2.2e-30 104.8 1.7 7e-30 103.2 1.7 1.9 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 GBG61649.1 - 0.019 14.2 0.1 0.019 14.2 0.1 2.1 1 1 0 2 2 2 0 Tubulin like Tubulin PF00091.25 GBG61650.1 - 2e-42 145.7 0.2 2e-42 145.7 0.2 2.2 3 0 0 3 3 3 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 GBG61650.1 - 2.1e-30 104.9 1.7 6.4e-30 103.3 1.7 1.9 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 GBG61650.1 - 0.021 14.0 0.1 0.021 14.0 0.1 2.1 1 1 0 2 2 2 0 Tubulin like Methyltransf_21 PF05050.12 GBG61651.1 - 6.5e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain MFS_1 PF07690.16 GBG61652.1 - 3.5e-28 98.5 48.4 3.5e-28 98.5 48.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CNOT11 PF10155.9 GBG61653.1 - 2.1e-53 179.8 7.8 3.1e-53 179.2 7.8 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Creb_binding PF09030.10 GBG61653.1 - 0.047 14.4 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Creb binding Glyco_hydro_38N PF01074.22 GBG61654.1 - 3.6e-88 295.7 5.5 4.9e-88 295.2 5.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GBG61654.1 - 6.7e-50 170.1 0.0 1e-49 169.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GBG61654.1 - 1.1e-18 67.1 0.2 2.8e-18 65.9 0.2 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GBG61654.1 - 9e-08 32.1 0.0 2.1e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain TetR_C_11 PF16859.5 GBG61654.1 - 0.073 13.4 0.1 0.95 9.8 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RT_RNaseH_2 PF17919.1 GBG61655.1 - 4.3e-25 87.7 0.0 1.1e-24 86.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61655.1 - 3.1e-21 75.6 0.0 6.7e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61655.1 - 1.5e-11 44.2 0.1 3.5e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61655.1 - 0.0002 21.6 0.1 0.00062 19.9 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG61655.1 - 0.024 14.5 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG61656.1 - 0.00064 19.9 0.2 0.0047 17.2 0.0 2.5 2 1 0 2 2 2 1 Retrotransposon gag protein CLZ PF16526.5 GBG61656.1 - 0.22 11.9 1.9 0.79 10.1 0.8 2.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BTB_2 PF02214.22 GBG61657.1 - 2e-16 60.1 0.1 9.8e-16 57.9 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain DUF3138 PF11336.8 GBG61658.1 - 0.06 11.9 2.5 0.12 10.9 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Herpes_UL25 PF01499.16 GBG61658.1 - 4.4 5.7 6.2 8.1 4.8 6.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family REV PF00424.18 GBG61658.1 - 7.4 6.7 8.1 0.71 9.9 0.7 2.8 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Presenilin PF01080.17 GBG61659.1 - 0.18 10.6 1.9 9 4.9 1.2 2.0 2 0 0 2 2 2 0 Presenilin DUF2052 PF09747.9 GBG61659.1 - 5.4 7.1 24.8 0.81 9.8 0.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) pP_pnuc_2 PF18166.1 GBG61660.1 - 0.065 13.3 0.3 0.17 11.9 0.3 1.7 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease C2 PF00168.30 GBG61661.1 - 2.7e-10 40.4 0.0 5.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain RVT_1 PF00078.27 GBG61662.1 - 1.2e-31 110.0 0.3 2.9e-28 98.9 0.1 3.1 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) PI-PLC-Y PF00387.19 GBG61662.1 - 9.5e-22 77.5 0.4 3.3e-21 75.8 0.4 2.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain RT_RNaseH PF17917.1 GBG61662.1 - 9.3e-14 51.6 0.1 1.1e-12 48.1 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61662.1 - 6.6e-07 29.3 0.0 1.8e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG61662.1 - 0.0001 22.2 2.4 0.0001 22.2 2.4 2.7 2 0 0 2 2 2 1 Zinc knuckle DUF4187 PF13821.6 GBG61662.1 - 0.012 15.4 0.7 0.012 15.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG61662.1 - 0.015 15.5 2.5 0.016 15.4 0.2 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein TMEM247 PF15444.6 GBG61662.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.7 2 1 1 3 3 3 0 Transmembrane protein 247 RVT_1 PF00078.27 GBG61663.1 - 3.5e-58 196.8 0.4 1.3e-28 100.1 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PI-PLC-X PF00388.19 GBG61663.1 - 1.3e-46 157.8 0.0 2.6e-46 156.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain RT_RNaseH_2 PF17919.1 GBG61663.1 - 8.2e-24 83.5 0.0 2.6e-22 78.8 0.0 2.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61663.1 - 9.1e-24 83.8 0.0 2.5e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61663.1 - 2.7e-20 72.2 0.2 6e-20 71.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG61663.1 - 4e-12 46.1 0.0 1.9e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease rve PF00665.26 GBG61663.1 - 7.6e-09 35.8 0.0 3.3e-08 33.7 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG61663.1 - 5.7e-06 26.9 0.0 0.00025 21.6 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease Tudor-knot PF11717.8 GBG61663.1 - 0.00033 20.5 0.0 0.0009 19.1 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain gag-asp_proteas PF13975.6 GBG61663.1 - 0.00086 19.8 0.0 0.0026 18.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61663.1 - 0.0066 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG61663.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG61664.1 - 7.7e-26 90.1 0.0 1.3e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61664.1 - 2.4e-25 88.8 0.0 4.5e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61664.1 - 3.9e-11 42.9 0.4 2.2e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61665.1 - 3.9e-18 65.3 0.0 1.5e-17 63.4 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61665.1 - 1.5e-13 50.8 2.2 3.7e-07 29.9 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61665.1 - 5.8e-07 29.8 0.0 2.1e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61666.1 - 6e-17 61.8 0.0 1.5e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61666.1 - 7.7e-13 48.3 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase WTX PF09422.10 GBG61666.1 - 0.00067 18.9 3.5 0.0013 17.9 3.5 1.4 1 0 0 1 1 1 1 WTX protein RVP_2 PF08284.11 GBG61666.1 - 0.00074 19.3 0.1 0.0026 17.6 0.1 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease CHDCT2 PF08074.11 GBG61666.1 - 0.3 11.3 3.2 0.76 9.9 3.2 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF5130 PF17174.4 GBG61666.1 - 1 9.5 3.3 28 4.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5130) AAA_16 PF13191.6 GBG61666.1 - 1.1 9.6 5.1 1.4 9.2 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain RT_RNaseH_2 PF17919.1 GBG61668.1 - 1.7e-34 117.8 0.0 3.9e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61668.1 - 2.6e-29 101.6 0.1 7e-29 100.2 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61668.1 - 1.6e-26 93.2 0.0 3.1e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61668.1 - 9e-07 28.7 0.0 2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61668.1 - 0.011 16.4 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG61668.1 - 0.051 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG61669.1 - 1.1e-24 87.2 0.0 2.2e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NDUFA12 PF05071.16 GBG61669.1 - 3e-24 85.7 5.9 7.3e-24 84.4 5.9 1.7 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 RT_RNaseH_2 PF17919.1 GBG61669.1 - 3.4e-16 59.1 0.0 7.2e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61669.1 - 3.6e-05 24.0 0.0 9.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HAUS-augmin3 PF14932.6 GBG61670.1 - 3.8e-05 23.4 6.1 6.3e-05 22.7 6.1 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 ATG16 PF08614.11 GBG61670.1 - 9.4e-05 22.7 3.8 9.4e-05 22.7 3.8 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Filament PF00038.21 GBG61670.1 - 0.00056 19.6 8.5 0.0009 18.9 8.5 1.4 1 0 0 1 1 1 1 Intermediate filament protein FliD_C PF07195.12 GBG61670.1 - 0.0011 18.5 1.0 0.0018 17.8 1.0 1.3 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus DUF812 PF05667.11 GBG61670.1 - 0.0026 16.7 7.5 0.0029 16.6 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3450 PF11932.8 GBG61670.1 - 0.0035 16.7 3.2 0.0065 15.8 3.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 GBG61670.1 - 0.0036 17.3 12.4 0.0036 17.3 12.4 2.7 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.9 GBG61670.1 - 0.0048 17.1 9.4 0.0048 17.1 9.4 1.9 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 GBG61670.1 - 0.0061 16.6 16.0 0.0061 16.6 16.0 1.8 2 1 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 GBG61670.1 - 0.012 14.7 2.0 0.016 14.3 2.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 kleA_kleC PF17383.2 GBG61670.1 - 0.015 15.6 2.6 0.55 10.6 0.8 2.8 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A ABC_tran_CTD PF16326.5 GBG61670.1 - 0.02 15.1 7.9 0.02 15.1 7.9 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain FlxA PF14282.6 GBG61670.1 - 0.024 14.6 4.9 0.052 13.5 4.9 1.5 1 0 0 1 1 1 0 FlxA-like protein ZapB PF06005.12 GBG61670.1 - 0.037 14.5 10.7 0.037 14.5 10.7 2.6 2 1 1 3 3 2 0 Cell division protein ZapB zf-CpG_bind_C PF12269.8 GBG61670.1 - 0.04 13.7 3.8 0.065 13.0 3.8 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Nup54 PF13874.6 GBG61670.1 - 0.041 14.0 3.8 0.24 11.5 2.6 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 COG2 PF06148.11 GBG61670.1 - 0.078 13.1 8.2 0.036 14.1 5.7 1.8 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 KASH_CCD PF14662.6 GBG61670.1 - 0.097 12.5 17.2 0.3 10.9 17.2 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TFA2_Winged_2 PF18121.1 GBG61670.1 - 0.11 12.2 2.2 0.28 10.9 2.2 1.7 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 DUF4349 PF14257.6 GBG61670.1 - 0.11 11.9 3.4 0.19 11.1 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF4407 PF14362.6 GBG61670.1 - 0.11 11.8 0.8 0.17 11.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 GBG61670.1 - 0.13 12.4 10.3 0.083 13.1 7.8 1.9 2 1 1 3 3 1 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 GBG61670.1 - 0.15 12.4 12.7 0.25 11.7 8.1 2.8 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Gp-FAR-1 PF05823.12 GBG61670.1 - 0.15 12.4 7.6 0.074 13.4 3.3 2.2 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SKA2 PF16740.5 GBG61670.1 - 0.15 11.8 6.6 1.3 8.8 3.0 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 GBG61670.1 - 0.17 10.8 18.1 1.5 7.6 17.2 2.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 GBG61670.1 - 0.18 11.9 0.2 0.36 10.9 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 GBG61670.1 - 0.24 11.4 8.2 0.38 10.8 4.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 GBG61670.1 - 0.34 11.0 14.6 0.21 11.7 12.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 GBG61670.1 - 0.43 10.9 13.1 0.93 9.8 11.7 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 GBG61670.1 - 0.72 9.0 4.9 1.2 8.3 4.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein TMEM215 PF15746.5 GBG61670.1 - 0.78 9.2 4.0 1.4 8.3 4.0 1.3 1 0 0 1 1 1 0 TMEM215 family APG6_N PF17675.1 GBG61670.1 - 1.2 9.6 18.0 0.026 15.0 10.3 2.2 3 0 0 3 3 1 0 Apg6 coiled-coil region Med21 PF11221.8 GBG61670.1 - 2.3 8.5 18.2 2.8 8.2 7.1 3.0 2 1 1 3 3 3 0 Subunit 21 of Mediator complex FlaC_arch PF05377.11 GBG61670.1 - 2.5 8.6 11.1 2.1 8.8 3.7 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) AAA_23 PF13476.6 GBG61670.1 - 8 6.9 14.4 10 6.6 14.4 1.3 1 1 0 1 1 1 0 AAA domain DivIC PF04977.15 GBG61670.1 - 8.1 6.3 12.5 1.6 8.5 4.8 2.8 1 1 1 2 2 2 0 Septum formation initiator FAM76 PF16046.5 GBG61670.1 - 8.9 5.6 11.6 11 5.3 10.6 1.5 1 1 0 1 1 1 0 FAM76 protein YabA PF06156.13 GBG61670.1 - 9.1 7.0 10.7 3.2 8.4 7.0 2.1 2 1 0 2 2 2 0 Initiation control protein YabA Med4 PF10018.9 GBG61670.1 - 9.5 5.8 11.1 47 3.6 11.1 2.1 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 SCAPER_N PF16501.5 GBG61671.1 - 2.2e-14 53.2 1.8 2.2e-14 53.2 1.8 2.5 3 0 0 3 3 3 1 S phase cyclin A-associated protein in the endoplasmic reticulum PA26 PF04636.13 GBG61671.1 - 2.8 6.8 4.8 6 5.7 4.8 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RT_RNaseH PF17917.1 GBG61672.1 - 3.4e-24 85.1 0.0 8.8e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61672.1 - 1.2e-22 79.8 0.0 2.8e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61672.1 - 1.5e-09 38.0 0.0 6.3e-09 36.1 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG61672.1 - 3.2e-06 26.8 0.0 1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) WTX PF09422.10 GBG61672.1 - 0.31 10.1 7.8 0.14 11.2 4.6 1.9 1 1 1 2 2 2 0 WTX protein RVT_1 PF00078.27 GBG61673.1 - 0.00035 20.2 0.0 0.00067 19.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG61673.1 - 0.0053 16.5 0.3 0.3 10.9 0.1 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61673.1 - 0.027 15.0 0.0 0.07 13.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG61673.1 - 0.06 13.6 0.6 0.22 11.8 0.3 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Ku_N PF03731.15 GBG61673.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain RT_RNaseH_2 PF17919.1 GBG61674.1 - 1.1e-31 108.8 0.0 2.1e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61674.1 - 1e-28 99.6 0.1 2.1e-28 98.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61674.1 - 2.4e-17 62.8 0.1 4.7e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61674.1 - 1.9e-16 60.3 0.0 4.2e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61674.1 - 2.3e-05 24.5 0.0 6.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG61674.1 - 0.029 14.1 0.6 0.091 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) TetR_C_15 PF17918.1 GBG61674.1 - 0.046 14.5 0.0 0.14 12.9 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RT_RNaseH PF17917.1 GBG61675.1 - 2.3e-24 85.7 0.0 1.2e-23 83.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61675.1 - 8.7e-23 80.3 0.0 3.8e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG61675.1 - 1.8e-07 31.3 0.5 0.041 14.2 0.0 3.7 4 0 0 4 4 4 2 Retrotransposon gag protein RVT_1 PF00078.27 GBG61675.1 - 3.5e-06 26.7 0.0 1.2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61675.1 - 0.0034 17.2 0.0 0.0085 15.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Fanconi_A PF03511.14 GBG61675.1 - 0.13 12.2 0.1 0.36 10.8 0.1 1.7 1 0 0 1 1 1 0 Fanconi anaemia group A protein DUF1664 PF07889.12 GBG61675.1 - 3 7.9 9.9 0.85 9.7 0.5 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GBG61675.1 - 4.9 7.3 8.3 4.7 7.4 0.6 3.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family rve PF00665.26 GBG61676.1 - 7.3e-25 87.5 0.0 3.6e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG61676.1 - 8.1e-15 54.7 0.1 2.3e-14 53.2 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG61676.1 - 9.6e-08 31.8 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG61676.1 - 7.2e-05 22.5 0.1 0.055 13.2 0.0 3.0 3 0 0 3 3 3 2 Integrase core domain gag-asp_proteas PF13975.6 GBG61676.1 - 0.00091 19.7 0.0 0.0022 18.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG61676.1 - 0.0068 16.4 1.7 0.021 14.9 1.7 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 GBG61676.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG61676.1 - 0.056 14.1 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG61677.1 - 1.1e-35 123.1 0.0 1.2e-26 93.6 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG61678.1 - 6.8e-05 22.8 2.1 0.00019 21.4 2.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG61678.1 - 0.39 10.6 5.3 0.67 9.8 2.9 2.2 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 GBG61678.1 - 5.7 7.4 22.0 0.76 10.2 0.2 3.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G DUF4187 PF13821.6 GBG61679.1 - 0.021 14.6 0.8 0.056 13.2 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG61679.1 - 0.047 14.0 2.8 0.057 13.7 0.2 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 GBG61680.1 - 0.0074 16.5 3.6 0.048 13.9 0.1 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG61680.1 - 0.013 15.4 0.0 0.041 13.8 0.0 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain BLOC1_2 PF10046.9 GBG61680.1 - 0.92 9.9 7.4 0.43 10.9 2.9 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 GBG61680.1 - 3.7 7.1 7.2 22 4.6 0.1 2.4 2 0 0 2 2 2 0 fzo-like conserved region Baculo_PEP_C PF04513.12 GBG61680.1 - 8.9 6.3 9.0 24 5.0 8.7 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF659 PF04937.15 GBG61681.1 - 2.1e-37 128.3 0.0 4.2e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61681.1 - 1.7e-05 24.5 0.0 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region BSP_II PF05432.11 GBG61681.1 - 0.35 10.5 24.4 0.6 9.8 24.4 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Borrelia_P83 PF05262.11 GBG61681.1 - 2.5 6.5 15.7 3.8 5.9 15.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF966 PF06136.13 GBG61681.1 - 6.8 6.3 14.4 10 5.7 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RT_RNaseH_2 PF17919.1 GBG61682.1 - 1.4e-20 73.2 0.0 2.9e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61682.1 - 1.5e-18 67.0 0.0 3.3e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3338 PF11819.8 GBG61682.1 - 0.0019 18.2 3.3 0.13 12.2 0.1 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3338) Retrotrans_gag PF03732.17 GBG61682.1 - 0.013 15.8 0.3 0.013 15.8 0.3 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein rve PF00665.26 GBG61683.1 - 4.2e-12 46.3 0.0 6.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG61683.1 - 0.0042 17.1 1.1 0.0069 16.5 1.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG61684.1 - 2.3e-28 98.2 0.0 1.2e-27 95.8 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61684.1 - 2.1e-27 95.5 0.0 2.1e-27 95.5 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase BcsB PF03170.13 GBG61685.1 - 0.18 10.1 0.1 0.24 9.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit RVT_1 PF00078.27 GBG61686.1 - 3.2e-28 98.7 0.0 7.2e-28 97.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CTNNB1_binding PF08347.11 GBG61686.1 - 5.2e-05 23.5 2.1 0.079 13.1 0.2 2.6 2 0 0 2 2 2 2 N-terminal CTNNB1 binding Retrotrans_gag PF03732.17 GBG61686.1 - 0.0028 17.9 0.0 0.018 15.3 0.0 2.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF2730 PF10805.8 GBG61686.1 - 0.0093 16.0 4.0 1.3 9.1 0.2 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF2730) DUF4510 PF14971.6 GBG61686.1 - 0.054 13.8 21.8 1.3 9.4 6.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) Swi6_N PF18530.1 GBG61686.1 - 0.057 13.6 0.1 27 4.9 0.0 3.3 3 0 0 3 3 3 0 Swi6 N-terminal domain Trimer_CC PF08954.11 GBG61686.1 - 0.067 12.8 6.8 2.9 7.5 0.7 3.2 2 0 0 2 2 2 0 Trimerisation motif DUF3464 PF11947.8 GBG61686.1 - 1.4 8.6 4.7 13 5.5 0.4 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 TolA_bind_tri PF16331.5 GBG61686.1 - 6.4 6.9 21.8 0.72 10.0 2.1 3.9 4 0 0 4 4 4 0 TolA binding protein trimerisation PFEMP PF03011.15 GBG61686.1 - 9.9 6.8 14.1 14 6.3 3.4 2.5 2 0 0 2 2 2 0 PFEMP DBL domain Integrase_H2C2 PF17921.1 GBG61687.1 - 1.8e-18 66.4 0.3 3.9e-18 65.3 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG61687.1 - 3.5e-14 53.0 0.1 1.1e-13 51.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG61687.1 - 0.0097 15.8 0.0 0.45 10.5 0.0 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG61687.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DUF1564 PF07600.11 GBG61687.1 - 0.13 11.9 0.0 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG61688.1 - 1.3e-41 142.5 1.3 9.1e-28 97.3 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61688.1 - 6.8e-07 29.5 0.0 2e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain CENP-B_dimeris PF09026.10 GBG61688.1 - 0.036 14.4 8.2 0.1 13.0 3.4 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 GBG61688.1 - 3.3 7.4 11.1 6 6.5 11.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_60s PF00428.19 GBG61688.1 - 5.9 7.5 9.7 6.1 7.5 0.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein DNA_pol_phi PF04931.13 GBG61688.1 - 9.1 4.2 7.3 16 3.4 7.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Retrotrans_gag PF03732.17 GBG61689.1 - 0.00011 22.4 8.3 0.023 14.9 0.0 3.9 4 0 0 4 4 4 2 Retrotransposon gag protein CLZ PF16526.5 GBG61689.1 - 0.14 12.5 3.4 0.22 11.9 0.9 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 GBG61689.1 - 8.4 4.8 17.0 16 3.9 17.0 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family RVT_1 PF00078.27 GBG61690.1 - 3.9e-10 39.6 0.0 8.2e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61690.1 - 8.8e-10 38.5 0.0 2.2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61690.1 - 1.1e-07 32.4 0.0 3.6e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG61690.1 - 4.2e-07 29.9 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG61690.1 - 3.4e-06 27.5 0.0 9.3e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG61690.1 - 0.00024 21.4 0.0 0.00061 20.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG61690.1 - 0.0005 20.3 3.2 0.46 10.8 0.0 3.8 4 0 0 4 4 4 2 Retrotransposon gag protein Spc29 PF17082.5 GBG61690.1 - 0.013 15.4 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Spindle Pole Component 29 Asp_protease PF09668.10 GBG61690.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TolA_bind_tri PF16331.5 GBG61690.1 - 0.031 14.4 10.8 0.019 15.0 4.0 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF1664 PF07889.12 GBG61690.1 - 0.085 12.9 3.0 0.67 10.0 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-FCS PF06467.14 GBG61690.1 - 0.19 11.7 0.4 0.56 10.2 0.4 1.7 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif CorA PF01544.18 GBG61690.1 - 0.19 11.0 1.5 8.2 5.6 0.1 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SlyX PF04102.12 GBG61690.1 - 3.4 8.3 22.8 0.076 13.6 0.4 4.9 3 2 1 4 4 4 0 SlyX RVP_2 PF08284.11 GBG61691.1 - 1.7e-10 40.8 0.0 5.2e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61691.1 - 3.8e-08 33.9 0.0 9.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61691.1 - 1e-06 29.2 0.0 2.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61691.1 - 0.0041 16.9 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG61691.1 - 0.02 15.5 0.5 0.02 15.5 0.5 2.9 2 1 1 3 3 3 0 SlyX RVT_1 PF00078.27 GBG61692.1 - 7.4e-31 107.4 0.0 1.3e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61692.1 - 7.8e-19 67.6 0.0 1.2e-13 50.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61692.1 - 4.6e-12 45.9 0.0 1.8e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG61692.1 - 1.5e-08 34.9 0.0 2.3e-07 31.0 0.0 2.5 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61692.1 - 2.6e-08 34.0 0.0 5.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61692.1 - 0.0041 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG61693.1 - 1e-23 84.0 0.1 2e-23 83.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG61693.1 - 0.0047 17.2 1.1 0.023 15.0 0.3 2.6 3 1 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG61694.1 - 2.5e-22 78.8 0.1 1.7e-21 76.1 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61694.1 - 4.6e-22 78.3 0.1 1.6e-21 76.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61694.1 - 4.8e-16 58.6 0.2 1.1e-15 57.4 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61694.1 - 2.8e-08 34.0 0.0 8.9e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG61694.1 - 3.5e-07 30.1 0.0 7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61694.1 - 7.3e-07 29.8 0.0 1.6e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61694.1 - 5.2e-05 23.7 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG61694.1 - 6.2e-05 22.6 0.0 0.00016 21.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tudor-knot PF11717.8 GBG61694.1 - 0.0012 18.6 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG61694.1 - 0.018 14.9 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG61694.1 - 0.044 14.1 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG61697.1 - 3.1e-23 81.7 0.0 6.2e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61697.1 - 1.3e-21 76.8 0.0 1.5e-20 73.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61697.1 - 1e-05 25.1 0.0 2.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG61698.1 - 9.5e-27 93.9 0.1 1.9e-26 93.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61698.1 - 3.8e-21 75.0 0.0 8.3e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61698.1 - 2.9e-17 62.9 0.0 6.4e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG61698.1 - 1.1e-06 28.5 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61698.1 - 2.4e-06 28.1 0.0 1e-05 26.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61698.1 - 3.1e-05 24.4 0.0 7.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61698.1 - 0.0028 17.4 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG61698.1 - 0.094 13.0 0.1 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein CLZ PF16526.5 GBG61698.1 - 1.5 9.2 5.2 2.8 8.4 0.7 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RVT_1 PF00078.27 GBG61699.1 - 4.1e-27 95.2 0.1 2.3e-26 92.7 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61699.1 - 5.3e-26 90.6 0.0 1.6e-25 89.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61699.1 - 2.9e-25 88.6 0.0 6.6e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG61699.1 - 0.0012 19.0 12.4 0.0099 16.1 0.1 4.3 4 0 0 4 4 4 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG61699.1 - 0.013 16.1 7.5 0.013 16.1 7.5 3.5 4 0 0 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BLOC1_2 PF10046.9 GBG61699.1 - 0.05 13.9 7.1 0.057 13.7 2.9 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SPACA9 PF15120.6 GBG61699.1 - 0.066 13.0 1.5 0.23 11.2 1.3 2.0 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 DUF4211 PF13926.6 GBG61699.1 - 0.36 10.9 4.4 1.8 8.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4211) NPV_P10 PF05531.12 GBG61699.1 - 1.5 9.3 5.7 26 5.3 0.2 3.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.16 GBG61699.1 - 3.2 6.5 5.1 25 3.6 6.3 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein LCD1 PF09798.9 GBG61699.1 - 3.4 6.1 5.7 0.84 8.1 2.3 1.7 2 0 0 2 2 2 0 DNA damage checkpoint protein DUF659 PF04937.15 GBG61700.1 - 9.3e-24 84.0 0.0 1.8e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61700.1 - 3.3e-10 39.6 0.2 3.3e-10 39.6 0.2 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF5617 PF18493.1 GBG61700.1 - 0.083 13.0 0.7 0.84 9.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) SPOUT_MTase PF02590.17 GBG61701.1 - 0.46 10.4 8.1 0.041 13.9 2.1 1.9 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Sde2_N_Ubi PF13019.6 GBG61701.1 - 4.8 7.0 9.6 0.32 10.8 1.1 2.5 2 1 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain DUF659 PF04937.15 GBG61702.1 - 3.4e-34 117.9 0.3 3.4e-34 117.9 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61702.1 - 7.8e-09 35.2 0.1 2.1e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG61704.1 - 1.4e-32 111.7 0.0 2.6e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61704.1 - 2.6e-28 98.4 0.0 5e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61704.1 - 4.2e-18 65.2 0.1 1.3e-17 63.6 0.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG61704.1 - 4e-12 46.1 0.0 7.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61704.1 - 3e-09 37.1 0.0 6.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Phage_GPO PF05929.11 GBG61704.1 - 0.069 12.8 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG61705.1 - 1e-32 113.5 0.4 7.7e-12 45.2 0.2 4.5 3 1 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61705.1 - 1.6e-07 31.5 0.8 1.3e-06 28.6 0.2 2.7 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG61705.1 - 0.00082 19.2 3.5 0.024 14.5 0.1 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HCV_NS5a_C PF12941.7 GBG61705.1 - 0.018 14.9 0.9 0.064 13.1 0.5 2.0 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region E1-E2_ATPase PF00122.20 GBG61705.1 - 0.079 12.5 0.2 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 E1-E2 ATPase RVT_1 PF00078.27 GBG61706.1 - 4e-23 82.1 0.1 6.4e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-Q PF13094.6 GBG61707.1 - 0.019 15.2 5.4 0.03 14.5 5.4 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit AC_N PF16214.5 GBG61707.1 - 0.77 8.8 3.9 1 8.4 3.9 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region RVT_1 PF00078.27 GBG61708.1 - 2.4e-06 27.2 0.0 4.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG61708.1 - 0.0026 18.0 2.4 0.0068 16.7 0.5 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG61708.1 - 0.0087 15.8 0.2 0.031 14.1 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) NCKAP5 PF15246.6 GBG61708.1 - 0.017 14.8 1.2 0.026 14.1 1.2 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DUF2894 PF11445.8 GBG61708.1 - 1.2 9.5 12.8 0.19 12.2 6.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2894) Retrotrans_gag PF03732.17 GBG61709.1 - 0.13 12.5 1.7 26 5.2 0.0 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein DUF4288 PF14119.6 GBG61709.1 - 0.58 10.6 3.8 1.4 9.4 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) RVT_1 PF00078.27 GBG61710.1 - 5.3e-16 58.8 0.6 4.6e-07 29.6 0.1 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61710.1 - 7e-07 29.5 0.2 3e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG61710.1 - 1e-05 25.5 0.0 3.7e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG61710.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CENP-K PF11802.8 GBG61710.1 - 0.014 15.0 2.4 0.028 14.0 2.4 1.4 1 0 0 1 1 1 0 Centromere-associated protein K TMEM247 PF15444.6 GBG61710.1 - 0.019 15.0 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 247 Retrotrans_gag PF03732.17 GBG61710.1 - 0.023 15.0 0.5 0.15 12.4 0.5 2.4 1 0 0 1 1 1 0 Retrotransposon gag protein AC_N PF16214.5 GBG61710.1 - 0.58 9.2 3.5 1.4 8.0 3.5 1.5 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region CENP-K PF11802.8 GBG61711.1 - 0.0028 17.3 2.2 0.0051 16.4 2.2 1.4 1 0 0 1 1 1 1 Centromere-associated protein K TMEM247 PF15444.6 GBG61711.1 - 0.018 15.1 0.1 0.018 15.1 0.1 1.8 2 0 0 2 2 2 0 Transmembrane protein 247 Retrotrans_gag PF03732.17 GBG61711.1 - 0.046 14.0 0.6 0.046 14.0 0.6 2.4 3 0 0 3 3 3 0 Retrotransposon gag protein TFIIA PF03153.13 GBG61711.1 - 0.26 11.3 19.0 0.12 12.4 16.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3499 PF12005.8 GBG61711.1 - 1.6 9.3 11.7 0.56 10.8 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Caudo_TAP PF02413.17 GBG61711.1 - 2 8.6 11.8 0.28 11.3 1.5 2.8 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK ATP-synt_E PF05680.12 GBG61711.1 - 2.6 8.4 11.4 0.21 11.9 0.3 2.6 2 0 0 2 2 2 0 ATP synthase E chain Cation_ATPase PF13246.6 GBG61712.1 - 3.1e-13 49.6 0.0 6.2e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) zf-CCHC PF00098.23 GBG61712.1 - 0.012 15.7 4.3 0.023 14.8 4.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG61712.1 - 0.059 13.2 0.6 0.13 12.1 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG61712.1 - 0.098 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-RVT PF13966.6 GBG61713.1 - 1.7e-05 25.5 0.5 6.4e-05 23.6 0.5 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 GBG61713.1 - 0.077 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG61714.1 - 6.8e-16 58.5 0.0 2.3e-15 56.8 0.0 1.8 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61714.1 - 3.6e-07 30.4 0.0 9.8e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Hydrolase PF00702.26 GBG61715.1 - 7e-11 42.8 7.3 4.8e-10 40.1 5.1 3.1 4 1 0 4 4 4 1 haloacid dehalogenase-like hydrolase DUF659 PF04937.15 GBG61715.1 - 7.1e-11 42.2 0.1 2.3e-10 40.5 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) Hydrolase_3 PF08282.12 GBG61715.1 - 0.0012 18.6 1.5 0.0022 17.8 0.5 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNA_GG_bind PF10258.9 GBG61715.1 - 0.024 14.7 0.1 0.059 13.4 0.1 1.6 1 0 0 1 1 1 0 PHAX RNA-binding domain RVT_1 PF00078.27 GBG61715.1 - 0.052 13.1 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG61716.1 - 1.1e-27 97.0 0.0 1.8e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cation_ATPase_C PF00689.21 GBG61716.1 - 2.5e-19 69.7 0.2 4.2e-19 69.0 0.2 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus RVP_2 PF08284.11 GBG61716.1 - 2.4e-07 30.6 0.0 4.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61716.1 - 0.00035 21.2 0.1 0.0014 19.2 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61716.1 - 0.022 15.3 0.0 0.15 12.6 0.0 2.2 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease Protocadherin PF08374.11 GBG61717.1 - 0.13 12.2 3.3 0.3 11.0 3.3 1.5 1 0 0 1 1 1 0 Protocadherin GerPC PF10737.9 GBG61717.1 - 0.22 11.6 12.0 0.18 11.9 2.1 2.4 2 0 0 2 2 2 0 Spore germination protein GerPC DNA_pack_N PF02500.15 GBG61717.1 - 0.63 9.8 5.6 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Zip PF02535.22 GBG61717.1 - 2.2 7.4 6.1 3.1 6.9 6.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RVT_1 PF00078.27 GBG61718.1 - 4.6e-27 95.0 0.0 9e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61718.1 - 1.3e-24 86.1 0.0 3.3e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61718.1 - 2.9e-21 75.7 0.0 7e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61718.1 - 9e-09 35.6 0.0 2.8e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Cation_ATPase_C PF00689.21 GBG61718.1 - 6.1e-08 32.6 0.2 1e-07 31.8 0.2 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Asp_protease_2 PF13650.6 GBG61718.1 - 8.1e-08 32.8 0.0 3.2e-07 30.9 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61718.1 - 6.5e-06 26.6 0.0 2.6e-05 24.7 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG61718.1 - 2.4e-05 24.1 0.2 0.27 11.2 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG61718.1 - 6.4e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG61718.1 - 0.0084 16.4 0.1 0.22 11.8 0.0 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG61718.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF3222 PF11519.8 GBG61722.1 - 6.3 7.1 6.3 45 4.4 0.2 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3222) DUF3222 PF11519.8 GBG61723.1 - 1.5 9.1 5.5 5.8 7.2 0.2 3.0 2 2 2 4 4 4 0 Protein of unknown function (DUF3222) DUF659 PF04937.15 GBG61724.1 - 3e-28 98.6 0.1 7.1e-28 97.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG61724.1 - 7.8e-17 61.5 0.8 1.8e-16 60.3 0.8 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61724.1 - 5.9e-16 58.7 0.1 1.1e-15 57.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61724.1 - 1.3e-09 38.0 0.1 3.1e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61725.1 - 3.5e-10 40.1 0.2 7.8e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SURF2 PF05477.11 GBG61725.1 - 0.033 13.9 4.2 0.054 13.2 4.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Retrotrans_gag PF03732.17 GBG61725.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Na_trans_assoc PF06512.13 GBG61725.1 - 0.76 10.0 13.9 1.4 9.2 13.9 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Lin-8 PF03353.15 GBG61725.1 - 1.2 8.7 10.2 2.2 7.8 10.2 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG61725.1 - 1.9 6.6 22.4 2.6 6.2 22.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG61725.1 - 2.2 7.6 23.7 3.1 7.1 23.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG61725.1 - 4.7 5.4 16.2 6.5 4.9 16.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG61726.1 - 4.4e-33 114.7 0.0 7.3e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MurB_C PF02873.16 GBG61727.1 - 1e-23 83.6 0.0 2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 GBG61727.1 - 1.2e-22 80.2 0.3 2.1e-22 79.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain RT_RNaseH_2 PF17919.1 GBG61728.1 - 1e-24 86.4 0.0 2.3e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61728.1 - 1.7e-24 86.6 0.0 2.9e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61728.1 - 1.6e-23 82.9 0.1 2e-22 79.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase P4Ha_N PF08336.11 GBG61728.1 - 0.24 11.4 1.5 2.4 8.2 0.1 2.7 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region ATG16 PF08614.11 GBG61728.1 - 2.3 8.4 6.9 2.3 8.4 4.9 2.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Retrotrans_gag PF03732.17 GBG61729.1 - 0.00032 20.9 2.8 0.0012 19.1 0.1 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG61729.1 - 0.012 15.4 0.7 0.036 13.8 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) SlyX PF04102.12 GBG61729.1 - 0.82 10.3 7.0 0.22 12.2 0.8 2.9 3 0 0 3 3 3 0 SlyX GRIM-19 PF06212.12 GBG61731.1 - 7.9 6.4 6.7 13 5.7 6.7 1.4 1 0 0 1 1 1 0 GRIM-19 protein RT_RNaseH PF17917.1 GBG61732.1 - 2e-44 150.1 0.0 4.6e-25 87.9 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61732.1 - 6.3e-38 128.8 0.0 1.5e-27 95.6 0.0 3.6 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG61732.1 - 2.1e-30 105.5 0.0 4.3e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG61732.1 - 5.4e-28 98.0 0.1 1.1e-27 97.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plant_tran PF04827.14 GBG61732.1 - 5.5e-10 39.2 0.5 1.1e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 Plant transposon protein Asp_protease_2 PF13650.6 GBG61732.1 - 6.2e-06 26.8 0.0 1.4e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61732.1 - 1.2e-05 25.7 0.0 3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61732.1 - 8e-05 22.4 0.0 0.0005 19.9 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG61732.1 - 8.8e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DBD_Tnp_Hermes PF10683.9 GBG61732.1 - 0.00019 21.0 0.0 0.00052 19.6 0.0 1.8 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain Retrotrans_gag PF03732.17 GBG61732.1 - 0.024 14.9 0.1 0.095 13.0 0.1 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein DDE_Tnp_1 PF01609.21 GBG61732.1 - 0.047 13.3 0.0 0.047 13.3 0.0 3.4 4 0 0 4 4 4 0 Transposase DDE domain RVT_1 PF00078.27 GBG61733.1 - 6.1e-31 107.7 0.1 9.1e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG61733.1 - 6.1e-08 33.1 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61733.1 - 1e-07 32.4 0.0 2.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG61733.1 - 1.3e-06 28.2 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG61733.1 - 7.4e-06 25.9 0.0 1.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG61733.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG61733.1 - 0.00016 21.7 0.1 0.00032 20.7 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain CDH1_2_SANT_HL1 PF18375.1 GBG61733.1 - 0.22 12.2 0.0 0.47 11.2 0.0 1.4 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 RVT_1 PF00078.27 GBG61734.1 - 5e-58 196.2 0.6 5.3e-32 111.1 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61734.1 - 7.8e-31 106.5 0.2 6.7e-30 103.5 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61734.1 - 1.1e-30 105.6 0.0 4.9e-30 103.5 0.0 2.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61734.1 - 4.6e-18 65.1 1.1 1.1e-17 63.9 1.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61734.1 - 3.2e-14 53.1 0.0 1e-13 51.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Calpain_III PF01067.22 GBG61734.1 - 9.1e-05 22.7 0.2 9.1e-05 22.7 0.2 2.8 3 0 0 3 3 3 1 Calpain large subunit, domain III zf-H2C2 PF09337.10 GBG61734.1 - 0.025 14.8 0.6 0.07 13.4 0.1 2.1 2 0 0 2 2 2 0 H2C2 zinc finger COMM_domain PF07258.14 GBG61734.1 - 0.042 14.0 0.0 1.1 9.4 0.0 2.9 2 0 0 2 2 2 0 COMM domain Integrase_H2C2 PF17921.1 GBG61735.1 - 5.3e-14 52.1 1.4 5.3e-14 52.1 1.4 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG61735.1 - 3.6e-09 36.8 0.0 1.4e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61735.1 - 0.027 14.7 0.1 0.063 13.5 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG61735.1 - 0.044 14.1 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Peptidase_C2 PF00648.21 GBG61736.1 - 1.2e-06 27.8 5.9 1.5e-06 27.4 5.9 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Integrase_H2C2 PF17921.1 GBG61737.1 - 2.1e-34 117.4 0.4 2.3e-18 66.1 0.1 2.9 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG61737.1 - 6.9e-24 84.1 0.0 1.2e-21 77.0 0.0 3.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61737.1 - 3.4e-18 65.5 0.0 8.1e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG61737.1 - 8.6e-06 25.9 0.1 0.052 13.8 0.0 2.9 2 0 0 2 2 2 2 H2C2 zinc finger Tudor-knot PF11717.8 GBG61737.1 - 0.00044 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RVT_1 PF00078.27 GBG61737.1 - 0.0007 19.2 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG61737.1 - 0.0063 16.8 0.1 0.047 14.0 0.0 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG61737.1 - 0.0074 16.2 0.0 0.062 13.2 0.0 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC_2 PF13696.6 GBG61737.1 - 0.2 11.5 8.8 0.035 13.9 1.0 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG61737.1 - 0.44 10.7 6.3 1.2 9.3 1.5 3.2 2 0 0 2 2 2 0 Zinc knuckle Peptidase_C2 PF00648.21 GBG61738.1 - 8.5e-52 176.0 0.0 1.2e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease RVT_1 PF00078.27 GBG61739.1 - 4.9e-32 111.2 0.0 1.1e-31 110.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61739.1 - 3.1e-31 107.4 0.0 8.5e-31 106.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61739.1 - 2.4e-30 104.9 0.0 6.2e-30 103.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1840 PF08895.11 GBG61739.1 - 0.024 15.0 12.7 0.04 14.2 3.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) ABC_membrane PF00664.23 GBG61740.1 - 5.5e-58 196.8 3.8 7.2e-58 196.4 3.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GBG61740.1 - 8e-32 110.6 0.0 1.6e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GBG61740.1 - 0.0009 18.7 0.0 0.0062 16.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GBG61740.1 - 0.008 16.5 0.0 0.053 13.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GBG61740.1 - 0.021 14.4 0.1 0.09 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GBG61740.1 - 0.027 14.9 0.6 0.075 13.4 0.0 2.1 3 1 0 3 3 3 0 AAA ATPase domain AAA_PrkA PF08298.11 GBG61740.1 - 0.029 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain RsgA_GTPase PF03193.16 GBG61740.1 - 0.093 12.6 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 GBG61740.1 - 0.11 12.5 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF1564 PF07600.11 GBG61742.1 - 0.0076 15.9 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) RT_RNaseH_2 PF17919.1 GBG61743.1 - 2.3e-13 50.0 0.0 1.1e-12 47.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61743.1 - 2.2e-06 27.3 0.3 7.4e-06 25.6 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61743.1 - 2.9e-06 27.4 0.3 1.5e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG61743.1 - 0.00067 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61743.1 - 0.00088 19.9 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG61743.1 - 0.0033 17.7 0.0 0.013 15.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG61743.1 - 0.012 16.1 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG61743.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG61743.1 - 0.099 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG61744.1 - 9.2e-29 100.5 0.1 8.9e-28 97.3 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61744.1 - 1.7e-23 82.5 0.0 6.3e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61744.1 - 1.2e-21 77.0 0.0 3.2e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61744.1 - 5.5e-17 61.6 0.1 1.2e-16 60.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain SlyX PF04102.12 GBG61744.1 - 0.009 16.6 0.2 0.009 16.6 0.2 4.0 5 0 0 5 5 5 1 SlyX Retrotrans_gag PF03732.17 GBG61744.1 - 0.01 16.1 0.0 0.063 13.6 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG61745.1 - 9.1e-29 100.5 0.1 8.8e-28 97.3 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61745.1 - 1.7e-23 82.5 0.0 6.3e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61745.1 - 1.2e-21 77.0 0.0 3.1e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61745.1 - 5.9e-17 61.5 0.1 1.2e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain SlyX PF04102.12 GBG61745.1 - 0.009 16.6 0.2 0.009 16.6 0.2 4.0 5 0 0 5 5 5 1 SlyX Retrotrans_gag PF03732.17 GBG61745.1 - 0.01 16.1 0.0 0.063 13.6 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG61746.1 - 2.8e-15 56.2 0.3 5.5e-15 55.2 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61746.1 - 2.7e-13 50.2 0.0 5.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain NYD-SP28_assoc PF14775.6 GBG61746.1 - 7.7 6.7 9.0 2.8 8.1 5.0 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain DHR10 PF18595.1 GBG61747.1 - 0.083 12.9 0.2 0.083 12.9 0.2 2.4 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain ATG16 PF08614.11 GBG61747.1 - 3.3 7.9 6.4 0.37 11.0 1.3 1.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) RT_RNaseH_2 PF17919.1 GBG61748.1 - 1.1e-31 108.8 0.0 2.3e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61748.1 - 6.8e-29 100.2 0.1 1.3e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61748.1 - 1.9e-14 53.7 0.2 1.7e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61748.1 - 1.1e-12 48.2 0.0 3.1e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG61748.1 - 9e-06 26.2 0.0 4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61748.1 - 8.5e-05 23.1 0.0 0.00065 20.3 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG61748.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG61748.1 - 0.097 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG61749.1 - 1.7e-27 96.4 0.1 3.3e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61749.1 - 1.3e-12 47.9 0.1 4.4e-12 46.2 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61749.1 - 4.7e-06 26.6 0.0 2e-05 24.6 0.0 2.1 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG61749.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DBD_Tnp_Hermes PF10683.9 GBG61750.1 - 1.2e-05 24.9 0.0 3.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain RVT_1 PF00078.27 GBG61751.1 - 2.2e-28 99.3 0.1 3.4e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG61751.1 - 2.1e-19 69.4 0.3 8.6e-19 67.4 0.3 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG61751.1 - 1.3e-18 67.2 0.0 3.1e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61751.1 - 1.1e-16 60.7 0.0 3.2e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61751.1 - 3.4e-09 36.9 0.0 1.2e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG61751.1 - 2e-07 31.6 0.0 4.9e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61751.1 - 6.3e-07 29.9 0.0 1.4e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG61751.1 - 6.9e-07 29.1 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG61751.1 - 0.00026 20.8 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG61751.1 - 0.066 13.4 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger DUF3006 PF11213.8 GBG61751.1 - 0.43 10.8 1.5 1.5 9.1 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Rep_fac-A_C PF08646.10 GBG61752.1 - 2.9e-34 117.9 1.8 1.3e-32 112.6 0.8 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 GBG61752.1 - 1.9e-24 85.4 2.6 1.3e-22 79.6 0.2 3.3 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 GBG61752.1 - 1.4e-20 73.2 1.5 3.5e-18 65.5 0.1 3.2 3 0 0 3 3 3 2 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 GBG61752.1 - 1.5e-10 40.9 0.8 1.2e-08 34.8 0.0 2.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 GBG61752.1 - 0.00046 20.0 0.1 0.17 11.6 0.0 2.9 3 1 0 3 3 3 2 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 GBG61752.1 - 0.00074 19.8 0.0 0.0022 18.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF223 zinc-ribbons_6 PF07191.12 GBG61752.1 - 0.15 12.1 1.2 0.32 11.0 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbons RRN3 PF05327.11 GBG61753.1 - 2.5e-46 158.4 2.5 2.5e-46 158.4 2.5 2.5 3 0 0 3 3 3 1 RNA polymerase I specific transcription initiation factor RRN3 RVT_1 PF00078.27 GBG61753.1 - 7.4e-14 51.8 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61753.1 - 2.5e-09 37.4 0.0 7.7e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG61753.1 - 3.2e-08 33.4 0.0 1.5e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61753.1 - 2.2e-07 31.4 0.0 7.6e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61753.1 - 2e-05 25.0 0.0 7.9e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG61753.1 - 0.00041 20.2 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG61753.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Chromo PF00385.24 GBG61753.1 - 0.075 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG61754.1 - 6.7e-10 39.2 0.0 1.8e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG61754.1 - 1.5e-07 31.1 0.0 2.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61754.1 - 0.00026 20.7 0.0 0.00066 19.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Vac_Fusion PF02346.16 GBG61754.1 - 0.056 13.1 0.7 9.6 5.9 0.0 2.9 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF2730 PF10805.8 GBG61755.1 - 0.021 14.9 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) PTS_IIA PF02255.16 GBG61755.1 - 0.089 12.8 0.4 0.089 12.8 0.4 2.3 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DDRGK PF09756.9 GBG61755.1 - 0.16 11.5 6.0 0.27 10.8 6.0 1.3 1 0 0 1 1 1 0 DDRGK domain DUF775 PF05603.12 GBG61755.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF775) RVT_1 PF00078.27 GBG61756.1 - 3.1e-26 92.3 0.0 4.4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61756.1 - 2e-09 37.4 0.0 6.3e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61756.1 - 0.00053 20.3 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG61756.1 - 0.0054 16.5 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease APG17 PF04108.12 GBG61756.1 - 0.033 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 RRN3 PF05327.11 GBG61757.1 - 1.9e-46 158.8 0.1 2.7e-46 158.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Integrase_H2C2 PF17921.1 GBG61758.1 - 3.1e-13 49.6 1.7 4.5e-13 49.1 0.4 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG61758.1 - 1.4e-12 47.8 0.0 6.2e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG61758.1 - 6.8e-05 23.4 0.1 0.00023 21.8 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61758.1 - 0.00086 19.8 0.2 0.0035 17.9 0.2 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1749 PF08538.10 GBG61759.1 - 2.1e-16 59.9 0.1 2.2e-16 59.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF1749 PF08538.10 GBG61760.1 - 1.3e-28 100.0 0.0 1.5e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) RVT_1 PF00078.27 GBG61761.1 - 1.7e-25 89.9 0.3 2.6e-24 86.0 0.0 2.6 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG61761.1 - 1.6e-14 53.7 0.7 4.2e-14 52.4 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG61761.1 - 1.3e-13 51.1 0.2 3.2e-13 49.9 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61761.1 - 6e-09 36.1 0.0 1.9e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG61761.1 - 7e-07 29.2 0.0 1.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG61761.1 - 0.0035 17.1 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG61761.1 - 0.019 15.2 0.0 0.062 13.6 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG61762.1 - 1.1e-25 89.6 0.0 2.2e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61762.1 - 3.3e-23 82.0 0.0 6.2e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61762.1 - 6.4e-16 58.6 0.0 1.3e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG61762.1 - 2.5e-15 56.6 0.1 4.3e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG61762.1 - 6.5e-13 48.6 0.0 1.7e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG61762.1 - 0.028 14.2 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Rhamno_transf PF11316.8 GBG61762.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF2070 PF09843.9 GBG61763.1 - 6.8 4.8 20.9 12 4.0 20.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) rve PF00665.26 GBG61764.1 - 1.5e-13 51.0 0.0 1.3e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG61764.1 - 8.7e-13 48.0 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG61764.1 - 2.9e-10 40.1 1.2 1.1e-09 38.2 0.1 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG61764.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Dppa2_A PF14049.6 GBG61764.1 - 0.15 12.2 0.2 0.35 11.0 0.2 1.5 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates Cpn10 PF00166.21 GBG61765.1 - 6.5e-45 151.1 3.5 1.2e-30 105.4 0.2 2.2 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit TPR_1 PF00515.28 GBG61766.1 - 5.3e-23 79.8 0.7 3.9e-08 32.8 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG61766.1 - 8.7e-20 70.1 2.2 1.4e-07 31.1 0.1 4.3 1 1 3 4 4 4 4 TPR repeat TPR_2 PF07719.17 GBG61766.1 - 3.6e-19 67.3 6.1 2.2e-05 24.2 0.1 4.8 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 GBG61766.1 - 4.2e-15 56.1 8.6 1.8e-05 25.3 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 GBG61766.1 - 6.4e-14 51.2 1.0 0.00089 19.5 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG61766.1 - 5.8e-12 44.8 0.1 0.0038 17.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG61766.1 - 2.7e-11 43.6 3.0 2.8e-05 24.3 0.2 4.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 GBG61766.1 - 1.3e-09 38.0 6.4 5.8e-07 29.6 0.6 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG61766.1 - 1.2e-08 35.0 8.4 0.006 17.3 0.1 4.4 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG61766.1 - 2e-08 34.6 11.3 0.00069 20.1 0.2 4.3 3 1 3 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 GBG61766.1 - 3.3e-08 33.0 0.4 0.39 10.8 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 GBG61766.1 - 4.6e-06 26.9 2.8 0.021 15.4 0.7 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG61766.1 - 6.6e-06 25.8 13.2 0.045 13.6 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat BTAD PF03704.17 GBG61766.1 - 0.00059 20.3 1.7 0.4 11.1 0.1 3.3 1 1 2 4 4 4 3 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 GBG61766.1 - 0.029 13.8 0.0 11 5.5 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR TPR_15 PF13429.6 GBG61766.1 - 0.07 12.3 1.2 0.46 9.6 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 GBG61766.1 - 0.077 13.1 0.2 3.9 7.5 0.0 3.2 2 2 2 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 GBG61766.1 - 0.25 12.1 10.2 96 4.1 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat zf-CCHC PF00098.23 GBG61767.1 - 1.9e-05 24.5 4.6 4.3e-05 23.4 4.6 1.7 1 0 0 1 1 1 1 Zinc knuckle SDA1 PF05285.12 GBG61767.1 - 0.00041 19.9 14.2 0.00041 19.9 14.2 4.8 3 2 1 4 4 4 1 SDA1 zf-CCHC_2 PF13696.6 GBG61767.1 - 0.027 14.3 3.5 0.068 13.0 3.5 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG61768.1 - 1.3e-05 25.1 2.2 2.4e-05 24.2 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG61768.1 - 0.0011 18.7 0.3 0.0011 18.7 0.3 1.7 2 0 0 2 2 2 1 Zinc knuckle SAP PF02037.27 GBG61768.1 - 0.0055 16.4 0.7 0.016 15.0 0.1 2.1 2 0 0 2 2 2 1 SAP domain AAA_13 PF13166.6 GBG61768.1 - 0.12 11.0 9.7 0.2 10.3 9.7 1.2 1 0 0 1 1 1 0 AAA domain zf-CCHC_3 PF13917.6 GBG61768.1 - 0.5 10.4 5.9 0.2 11.7 1.2 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF2570 PF10828.8 GBG61768.1 - 0.54 10.1 8.0 1.3 8.9 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) FUSC PF04632.12 GBG61768.1 - 1.3 7.5 10.3 1.8 7.0 10.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ALMT PF11744.8 GBG61768.1 - 2 7.1 7.9 2.8 6.7 7.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1682 PF07946.14 GBG61768.1 - 2.8 7.1 23.8 4.1 6.5 23.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Bul1_C PF04426.12 GBG61768.1 - 3.5 6.9 6.8 7.2 5.9 6.8 1.4 1 0 0 1 1 1 0 Bul1 C terminus Myb_DNA-bind_4 PF13837.6 GBG61769.1 - 1e-11 45.0 1.6 3.8e-11 43.2 0.4 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG61769.1 - 0.0014 18.9 0.1 0.0054 17.0 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG61769.1 - 1.7 8.8 5.4 0.36 10.9 1.4 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ribosomal_L7Ae PF01248.26 GBG61770.1 - 9.1e-11 41.3 0.1 1.8e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PdxJ PF03740.13 GBG61770.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ RVP_2 PF08284.11 GBG61771.1 - 5e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61771.1 - 1.4e-06 28.9 0.0 3.5e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61771.1 - 3.6e-05 24.2 0.1 0.00015 22.3 0.0 2.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG61771.1 - 0.0039 17.0 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG61771.1 - 0.023 14.5 0.0 0.18 11.6 0.0 2.3 2 1 0 2 2 2 0 Aspartyl protease DUF5401 PF17380.2 GBG61771.1 - 8.7 4.3 37.4 13 3.7 37.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) zf-C2H2_4 PF13894.6 GBG61772.1 - 0.003 18.3 0.8 0.012 16.4 0.8 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GBG61772.1 - 0.014 15.2 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 GBG61772.1 - 0.029 14.8 0.7 0.074 13.5 0.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 GBG61772.1 - 0.05 13.4 1.1 0.12 12.1 1.1 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type F-box-like PF12937.7 GBG61773.1 - 0.007 16.2 1.1 0.51 10.3 0.1 2.6 2 0 0 2 2 2 2 F-box-like FBD PF08387.10 GBG61773.1 - 0.0071 16.2 0.3 44 4.1 0.0 3.8 4 0 0 4 4 4 3 FBD F-box PF00646.33 GBG61773.1 - 0.089 12.7 0.9 4.1 7.4 0.0 3.1 2 1 0 2 2 2 0 F-box domain eIF3g PF12353.8 GBG61774.1 - 2.5e-35 121.6 0.6 3.4e-35 121.2 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 GBG61774.1 - 4.8e-20 71.2 0.3 3.7e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_2 PF13696.6 GBG61774.1 - 0.00011 21.9 3.3 0.00018 21.2 3.3 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4710 PF15828.5 GBG61774.1 - 0.03 14.5 1.9 0.053 13.7 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) RRM_occluded PF16842.5 GBG61774.1 - 0.06 13.2 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Lar_restr_allev PF14354.6 GBG61775.1 - 0.034 14.5 0.3 0.075 13.4 0.3 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar TFIIS_C PF01096.18 GBG61775.1 - 0.15 11.9 1.1 0.6 10.0 1.1 1.9 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) EF-hand_8 PF13833.6 GBG61776.1 - 5.1e-09 35.8 1.0 0.0026 17.6 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG61776.1 - 3.2e-06 26.3 2.2 0.00043 19.6 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GBG61776.1 - 8.7e-06 26.1 4.4 5.4e-05 23.6 4.7 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG61776.1 - 0.00072 19.3 2.3 0.069 13.1 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain Macoilin PF09726.9 GBG61777.1 - 0.032 12.8 2.8 0.044 12.3 2.8 1.1 1 0 0 1 1 1 0 Macoilin family XRCC1_N PF01834.16 GBG61779.1 - 5.5e-26 91.4 0.0 7.5e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 XRCC1 N terminal domain BRCT PF00533.26 GBG61779.1 - 4.4e-10 39.8 0.0 7.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GBG61779.1 - 1.3e-07 31.4 0.0 2.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 GBG61779.1 - 0.00028 21.2 0.2 0.0022 18.4 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DLH PF01738.18 GBG61780.1 - 1.3e-54 185.0 0.1 1.7e-54 184.7 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 GBG61780.1 - 1.1e-06 28.8 1.4 0.036 14.0 0.1 2.4 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 GBG61780.1 - 3.5e-05 23.4 0.2 0.16 11.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GBG61780.1 - 0.0035 17.2 0.3 1.6 8.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GBG61780.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 GBG61780.1 - 0.014 14.1 0.1 0.022 13.4 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF4813 PF16072.5 GBG61780.1 - 1 9.0 10.2 2.8 7.5 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) K_channel_TID PF07941.11 GBG61780.1 - 7.1 7.2 16.3 18 5.8 6.5 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF659 PF04937.15 GBG61781.1 - 1.8e-09 37.7 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61781.1 - 0.00046 19.9 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG61782.1 - 4.6e-10 39.5 0.0 7.8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61782.1 - 9.2e-06 25.4 0.1 3.1e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DTW PF03942.15 GBG61783.1 - 9.1e-17 61.4 0.1 1.6e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 DTW domain Eapp_C PF10238.9 GBG61783.1 - 0.064 13.3 4.6 1.1 9.3 0.3 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein 4HBT PF03061.22 GBG61783.1 - 0.092 13.1 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Thioesterase superfamily O-FucT PF10250.9 GBG61784.1 - 1.2e-11 44.9 0.0 1.3e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.9 GBG61785.1 - 1.5e-20 74.2 0.0 1.9e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PIG-X PF08320.12 GBG61786.1 - 9.6e-10 38.7 0.0 6.8e-05 22.9 0.0 3.2 2 1 0 2 2 2 2 PIG-X / PBN1 Radial_spoke PF04712.12 GBG61786.1 - 0.0026 16.8 1.4 0.0026 16.8 1.4 2.6 3 0 0 3 3 3 2 Radial spokehead-like protein Myc_N PF01056.18 GBG61786.1 - 2.6 7.8 12.5 0.63 9.9 0.0 3.2 3 0 0 3 3 3 0 Myc amino-terminal region Not1 PF04054.15 GBG61788.1 - 0.2 10.6 0.1 0.28 10.1 0.1 1.1 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 DUF2514 PF10721.9 GBG61788.1 - 0.4 10.7 7.5 1.2 9.2 7.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) BUD22 PF09073.10 GBG61788.1 - 0.89 8.8 5.6 1.3 8.3 5.6 1.2 1 0 0 1 1 1 0 BUD22 E1_dh PF00676.20 GBG61789.1 - 7.2e-114 379.8 0.0 8.5e-114 379.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 GBG61789.1 - 9.4e-05 22.2 0.3 0.00019 21.3 0.3 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 GBG61789.1 - 0.0021 17.4 0.2 0.0043 16.3 0.2 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.32 GBG61790.1 - 4.5e-12 46.3 6.3 0.0076 17.1 0.0 8.2 9 0 0 9 9 9 2 WD domain, G-beta repeat CENP-F_leu_zip PF10473.9 GBG61790.1 - 0.00041 20.4 11.2 0.00041 20.4 11.2 6.4 4 2 1 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PQQ_3 PF13570.6 GBG61790.1 - 0.0023 18.3 8.5 0.065 13.7 0.0 4.1 4 0 0 4 4 4 2 PQQ-like domain Laminin_II PF06009.12 GBG61790.1 - 0.0037 17.3 8.9 0.0037 17.3 8.9 5.1 2 2 2 5 5 5 1 Laminin Domain II ADIP PF11559.8 GBG61790.1 - 0.01 15.9 7.4 0.01 15.9 7.4 6.5 3 1 2 6 6 6 0 Afadin- and alpha -actinin-Binding Fungal_trans_2 PF11951.8 GBG61790.1 - 9.4 4.9 7.8 0.44 9.3 0.5 2.4 2 1 0 2 2 2 0 Fungal specific transcription factor domain SAPS PF04499.15 GBG61791.1 - 0.071 11.9 16.3 0.097 11.4 16.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CAF1 PF04857.20 GBG61791.1 - 0.13 11.4 9.3 0.2 10.8 9.3 1.5 1 0 0 1 1 1 0 CAF1 family ribonuclease Ribosomal_L13e PF01294.18 GBG61791.1 - 0.17 11.8 0.1 0.17 11.8 0.1 4.1 2 2 1 3 3 2 0 Ribosomal protein L13e PA26 PF04636.13 GBG61791.1 - 0.18 10.7 14.8 0.33 9.8 14.8 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GAGA_bind PF06217.12 GBG61791.1 - 1.7 8.9 19.6 4.1 7.6 19.6 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family PTPRCAP PF15713.5 GBG61791.1 - 2 8.7 35.1 3.7 7.8 35.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated LAP1C PF05609.12 GBG61791.1 - 3.8 6.5 25.5 6.4 5.8 25.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AUX_IAA PF02309.16 GBG61791.1 - 3.9 7.2 17.7 7.9 6.3 17.7 1.6 1 0 0 1 1 1 0 AUX/IAA family DUF913 PF06025.12 GBG61791.1 - 6.5 5.6 18.1 8 5.3 16.6 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GBG61791.1 - 8.5 5.0 35.7 12 4.5 35.7 1.2 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 GBG61791.1 - 9.2 4.5 10.8 12 4.1 10.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DPBB_1 PF03330.18 GBG61793.1 - 3.2e-12 46.6 0.2 1e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG61793.1 - 2.4e-10 40.3 0.0 4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen DUF5348 PF17295.2 GBG61793.1 - 0.094 12.6 0.1 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) DPBB_1 PF03330.18 GBG61794.1 - 4e-12 46.3 0.4 1e-11 45.0 0.0 1.9 3 0 0 3 3 3 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG61794.1 - 8.3e-10 38.6 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen DUF5348 PF17295.2 GBG61794.1 - 0.095 12.6 0.1 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) DPBB_1 PF03330.18 GBG61795.1 - 1.8e-12 47.4 0.0 5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG61795.1 - 1.1e-09 38.2 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen Glyco_hydro_9 PF00759.19 GBG61797.1 - 1e-113 380.9 0.1 1.4e-113 380.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 PEPCK_ATP PF01293.20 GBG61798.1 - 0 2017.6 0.0 1.1e-210 700.2 0.0 3.0 3 0 0 3 3 3 3 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 GBG61798.1 - 2.4e-07 30.7 0.2 0.19 11.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 GBG61798.1 - 1.1e-06 28.9 0.0 0.97 9.6 0.0 4.0 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 GBG61798.1 - 2.3e-05 24.1 0.0 1.8 8.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain DUF2840 PF11000.8 GBG61798.1 - 2.8e-05 24.0 0.0 6.5 6.5 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF2840) RC-P840_PscD PF10657.9 GBG61798.1 - 5.6e-05 23.3 0.0 0.41 10.7 0.0 2.7 2 0 0 2 2 2 2 Photosystem P840 reaction centre protein PscD Herpes_HEPA PF03324.14 GBG61798.1 - 0.00038 20.9 0.2 24 5.5 0.0 3.6 3 0 0 3 3 3 0 Herpesvirus DNA helicase/primase complex associated protein AAA_16 PF13191.6 GBG61798.1 - 0.00089 19.7 0.0 2.6 8.4 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 GBG61798.1 - 0.0014 18.6 6.1 3 7.7 0.1 3.4 3 0 0 3 3 3 2 RsgA GTPase DUF2961 PF11175.8 GBG61798.1 - 0.0044 16.7 0.2 28 4.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2961) PALP PF00291.25 GBG61798.1 - 0.0044 16.5 0.2 14 5.0 0.0 3.2 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme ABC_tran PF00005.27 GBG61798.1 - 0.0066 17.0 2.5 13 6.2 0.2 3.5 3 0 0 3 3 3 0 ABC transporter DUF4225 PF13988.6 GBG61798.1 - 0.017 14.7 0.3 45 3.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4225) AAA_30 PF13604.6 GBG61798.1 - 0.02 14.6 1.0 24 4.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain APT PF03440.14 GBG61798.1 - 0.023 14.6 0.1 85 3.2 0.0 3.6 3 0 0 3 3 3 0 Aerolysin/Pertussis toxin (APT) domain SRP54 PF00448.22 GBG61798.1 - 0.057 13.0 3.7 23 4.6 0.1 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Glyco_hydro_43 PF04616.14 GBG61798.1 - 0.11 11.8 0.0 76 2.5 0.0 3.1 3 0 0 3 3 3 0 Glycosyl hydrolases family 43 AAA_18 PF13238.6 GBG61798.1 - 0.36 11.4 1.1 70 4.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.6 GBG61798.1 - 0.39 9.3 2.2 17 3.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 GBG61798.1 - 0.61 10.4 8.7 21 5.4 0.0 4.3 6 0 0 6 6 3 0 AAA domain Hfq PF17209.3 GBG61798.1 - 0.95 9.2 3.3 1e+02 2.7 0.1 3.3 3 0 0 3 3 3 0 Hfq protein TetR_C_33 PF13305.6 GBG61798.1 - 1.2 9.9 3.1 2e+02 2.8 0.1 3.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain AAA_29 PF13555.6 GBG61798.1 - 2.5 7.9 8.7 30 4.5 0.2 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain ATP-synt_A PF00119.20 GBG61798.1 - 4.1 7.3 13.6 11 5.9 0.0 4.0 6 0 0 6 6 3 0 ATP synthase A chain PEPCK_ATP PF01293.20 GBG61801.1 - 4.8e-212 704.7 0.0 5.5e-212 704.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 GBG61801.1 - 0.14 12.3 0.0 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GBG61801.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DPBB_1 PF03330.18 GBG61802.1 - 1.8e-13 50.6 0.2 4e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG61802.1 - 1.2e-09 38.0 0.0 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen EF-hand_7 PF13499.6 GBG61803.1 - 1.2e-08 35.3 0.1 1.4e-05 25.4 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 GBG61803.1 - 9.8e-06 25.3 0.0 0.00021 21.1 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG61803.1 - 9.8e-05 22.0 0.0 0.0027 17.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GBG61803.1 - 0.00045 19.6 0.0 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.13 GBG61803.1 - 0.014 15.4 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 GBG61803.1 - 0.11 12.6 3.0 0.2 11.8 0.1 2.6 3 0 0 3 3 3 0 Ca2+ insensitive EF hand G-patch_2 PF12656.7 GBG61803.1 - 2.2 8.4 4.4 18 5.5 0.0 3.2 3 1 1 4 4 4 0 G-patch domain EF-hand_7 PF13499.6 GBG61804.1 - 3.3e-06 27.4 0.1 0.0073 16.7 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 GBG61804.1 - 2.2e-05 24.2 0.0 0.00016 21.5 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG61804.1 - 0.032 14.1 0.0 1.2 9.3 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 GBG61804.1 - 0.068 12.8 0.1 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 EF hand UPF0154 PF03672.13 GBG61804.1 - 0.076 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) 3D PF06725.11 GBG61805.1 - 6.2e-13 48.8 0.0 9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 3D domain 3D PF06725.11 GBG61806.1 - 6.2e-13 48.8 0.0 9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 3D domain Apolipoprotein PF01442.18 GBG61807.1 - 0.068 13.0 1.3 0.99 9.2 0.2 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Asp_protease_2 PF13650.6 GBG61808.1 - 0.00069 20.2 0.1 0.0026 18.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease ZapB PF06005.12 GBG61808.1 - 0.0033 17.8 6.4 0.0033 17.8 6.4 3.8 4 1 0 4 4 4 1 Cell division protein ZapB gag-asp_proteas PF13975.6 GBG61808.1 - 0.016 15.8 0.4 0.12 12.9 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease WASH-7_N PF14745.6 GBG61808.1 - 0.053 12.0 0.7 4.3 5.7 0.5 2.1 2 0 0 2 2 2 0 WASH complex subunit 7, N-terminal Prominin PF05478.11 GBG61808.1 - 0.08 10.9 1.4 0.12 10.3 1.4 1.2 1 0 0 1 1 1 0 Prominin DUF948 PF06103.11 GBG61808.1 - 0.29 11.4 0.9 0.75 10.1 0.9 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.7 GBG61810.1 - 1.4e-41 140.9 0.2 1.1e-13 51.6 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG61810.1 - 1.2e-38 131.0 1.0 1.5e-10 41.4 0.1 5.8 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG61810.1 - 1.2e-36 124.2 5.1 6.3e-10 39.1 0.1 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GBG61810.1 - 1.2e-35 120.3 0.7 1.1e-06 28.8 0.1 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 GBG61810.1 - 1.4e-31 105.0 0.0 6e-05 23.2 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Chromo PF00385.24 GBG61811.1 - 0.045 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain MLVIN_C PF18697.1 GBG61811.1 - 0.078 13.1 0.1 21 5.3 0.0 2.7 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF1564 PF07600.11 GBG61811.1 - 0.14 11.8 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) TEX12 PF15219.6 GBG61812.1 - 2.7 8.4 7.2 5.4 7.4 0.2 3.6 3 0 0 3 3 3 0 Testis-expressed 12 LRR_9 PF14580.6 GBG61813.1 - 1.3e-19 70.4 0.6 8.2e-16 58.0 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 GBG61813.1 - 3.3e-16 59.1 3.9 1.1e-06 28.8 0.4 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG61813.1 - 3.1e-12 46.1 14.2 7.7e-08 32.0 6.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat YabA PF06156.13 GBG61813.1 - 0.0061 17.2 7.8 0.0076 16.9 6.0 2.1 2 0 0 2 2 2 1 Initiation control protein YabA Retrotrans_gag PF03732.17 GBG61813.1 - 0.052 13.8 0.5 0.16 12.3 0.5 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Spc7 PF08317.11 GBG61813.1 - 0.1 11.5 9.6 0.22 10.4 9.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Calici_MSP PF05752.11 GBG61813.1 - 0.11 12.3 0.2 0.23 11.3 0.2 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein ADIP PF11559.8 GBG61813.1 - 0.42 10.7 12.6 0.92 9.6 12.6 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 GBG61813.1 - 2 7.2 10.2 3.4 6.4 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KELK PF15796.5 GBG61813.1 - 2.5 8.6 10.3 1.3 9.6 6.9 2.2 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase WEMBL PF05701.11 GBG61813.1 - 2.6 6.6 14.1 7 5.2 14.1 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light PCRF PF03462.18 GBG61813.1 - 4.8 7.0 6.5 7.3 6.4 4.6 2.2 2 0 0 2 2 2 0 PCRF domain LRR_6 PF13516.6 GBG61813.1 - 10 6.5 11.9 82 3.7 0.1 5.1 6 0 0 6 6 5 0 Leucine Rich repeat Pox_F11 PF04943.12 GBG61814.1 - 0.048 12.7 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein RVT_1 PF00078.27 GBG61816.1 - 1.3e-10 41.2 0.1 2.1e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61816.1 - 0.00034 20.6 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase YL1 PF05764.13 GBG61816.1 - 0.11 12.7 7.5 0.15 12.1 7.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GBG61816.1 - 0.57 8.3 5.2 0.69 8.1 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG61816.1 - 1.3 7.3 6.9 1.8 6.8 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PCRF PF03462.18 GBG61817.1 - 3.2e-74 249.0 3.5 5.7e-74 248.2 3.5 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 GBG61817.1 - 7.8e-37 125.8 1.6 7.8e-37 125.8 1.6 2.4 2 0 0 2 2 2 1 RF-1 domain DDE_Tnp_4 PF13359.6 GBG61817.1 - 5.1e-17 62.0 0.0 1e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61817.1 - 4.5e-09 36.2 0.0 2.6e-08 33.7 0.0 2.1 2 1 0 2 2 2 1 Plant transposon protein ABC_tran_CTD PF16326.5 GBG61817.1 - 0.0041 17.3 15.7 0.008 16.4 0.9 2.8 1 1 1 2 2 2 1 ABC transporter C-terminal domain DnaJ PF00226.31 GBG61817.1 - 0.033 14.3 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain ATG19_autophagy PF12744.7 GBG61817.1 - 0.32 10.2 1.9 0.55 9.4 1.9 1.3 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding Seryl_tRNA_N PF02403.22 GBG61817.1 - 0.69 10.2 5.1 0.97 9.7 3.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2514 PF10721.9 GBG61817.1 - 0.76 9.8 4.3 0.14 12.2 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) AAA_23 PF13476.6 GBG61817.1 - 1.4 9.4 3.7 1.1 9.7 0.5 2.1 2 0 0 2 2 2 0 AAA domain DnaJ_C PF01556.18 GBG61818.1 - 2.1e-35 122.0 0.0 2.9e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GBG61818.1 - 6.7e-26 90.2 4.2 1e-25 89.6 2.0 2.3 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GBG61818.1 - 1e-11 45.0 18.2 1.1e-11 44.9 16.7 1.9 1 1 1 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 GBG61818.1 - 0.081 12.9 12.0 1.1 9.3 3.4 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ_C PF01556.18 GBG61819.1 - 2.6e-35 121.7 0.0 3.5e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GBG61819.1 - 1.1e-25 89.5 4.6 1.2e-25 89.4 2.0 2.2 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GBG61819.1 - 1.2e-11 44.8 18.2 1.3e-11 44.7 16.7 1.8 1 1 1 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 GBG61819.1 - 0.1 12.6 12.0 1.2 9.1 3.4 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ_C PF01556.18 GBG61820.1 - 2.4e-35 121.8 0.0 3.3e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GBG61820.1 - 7.7e-26 90.0 4.2 1.1e-25 89.5 2.0 2.3 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GBG61820.1 - 1.2e-11 44.8 18.2 1.2e-11 44.8 16.7 1.9 1 1 1 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 GBG61820.1 - 0.092 12.7 12.0 1.2 9.2 3.4 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Coprogen_oxidas PF01218.18 GBG61822.1 - 4.6e-106 353.9 0.0 9.1e-106 352.9 0.0 1.5 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase DDE_Tnp_4 PF13359.6 GBG61823.1 - 2e-28 99.0 0.0 5.8e-27 94.3 0.0 2.4 2 1 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61823.1 - 6.1e-14 52.1 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61823.1 - 0.00011 21.9 0.1 0.21 11.2 0.0 2.4 2 1 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG61824.1 - 2.7e-08 34.1 3.0 5.8e-08 33.0 0.9 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG61824.1 - 0.02 15.2 0.2 0.057 13.7 0.2 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG61824.1 - 1.2 9.3 3.8 2.4 8.3 2.4 2.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain PPR_1 PF12854.7 GBG61825.1 - 9.9e-85 277.9 0.5 2e-08 33.8 0.0 14.1 14 0 0 14 14 14 11 PPR repeat PPR_2 PF13041.6 GBG61825.1 - 4.8e-84 276.4 24.0 4.7e-12 45.9 0.0 12.7 3 3 11 14 14 14 13 PPR repeat family PPR PF01535.20 GBG61825.1 - 2.3e-83 268.8 21.9 4.7e-08 32.8 0.3 14.6 14 0 0 14 14 14 13 PPR repeat PPR_3 PF13812.6 GBG61825.1 - 7.8e-64 211.7 1.2 4.3e-12 45.9 0.0 9.0 8 1 1 9 9 9 9 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG61825.1 - 8.3e-30 103.7 5.7 2.4e-08 33.6 0.0 5.3 2 2 3 5 5 5 5 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 GBG61825.1 - 5.6e-07 29.1 1.7 1.6 8.9 0.0 6.4 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG61825.1 - 1.5e-06 28.5 5.4 9.7 7.3 0.1 7.9 8 1 2 10 10 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG61825.1 - 2.1e-06 28.1 5.8 0.55 10.8 0.0 6.1 6 3 1 7 7 6 2 Tetratricopeptide repeat Clathrin PF00637.20 GBG61825.1 - 1.8e-05 24.6 0.0 12 5.8 0.0 5.3 4 1 2 6 6 6 0 Region in Clathrin and VPS ECSIT PF06239.11 GBG61825.1 - 0.0013 17.9 10.9 2.2 7.4 0.0 5.8 5 1 1 6 6 6 1 Evolutionarily conserved signalling intermediate in Toll pathway BKACE PF05853.12 GBG61825.1 - 0.0022 17.3 1.2 4.4 6.5 0.1 4.2 2 2 2 4 4 4 1 beta-keto acid cleavage enzyme RPM2 PF08579.11 GBG61825.1 - 0.0035 17.7 0.0 30 5.0 0.0 4.1 2 1 2 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) PI3K_1B_p101 PF10486.9 GBG61825.1 - 0.044 11.6 7.3 0.081 10.7 7.3 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TPR_12 PF13424.6 GBG61825.1 - 0.094 13.0 3.4 14 6.0 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GBG61825.1 - 0.11 12.5 1.4 99 2.8 0.0 4.7 4 2 2 6 6 5 0 Virulence factor membrane-bound polymerase, C-terminal TPR_10 PF13374.6 GBG61825.1 - 0.34 10.8 5.4 1.8 8.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MRP-S27 PF10037.9 GBG61825.1 - 1.1 8.0 9.2 8 5.2 0.0 4.2 4 0 0 4 4 4 0 Mitochondrial 28S ribosomal protein S27 Sigma70_ner PF04546.13 GBG61825.1 - 6.1 6.7 20.2 5.6 6.8 11.7 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region BSP_II PF05432.11 GBG61825.1 - 7.9 6.1 29.5 2.6 7.7 17.9 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Peptidase_M48_N PF16491.5 GBG61826.1 - 2.8e-67 226.2 5.8 6.2e-67 225.0 5.8 1.6 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 GBG61826.1 - 5.8e-48 163.3 0.0 9.1e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 GBG61826.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 GBG61826.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 SprT-like family WD40 PF00400.32 GBG61828.1 - 4.7e-18 65.2 11.2 0.0052 17.6 0.1 8.0 7 0 0 7 7 7 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 GBG61828.1 - 6.4e-11 41.9 10.9 1.6e-10 40.7 10.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG61828.1 - 3.9e-10 39.4 11.5 9.5e-10 38.2 11.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG61828.1 - 1.8e-09 37.3 7.7 4.4e-09 36.1 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG61828.1 - 2.5e-08 34.1 9.6 6.2e-08 32.9 9.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG61828.1 - 4.1e-07 29.9 9.2 1.1e-06 28.5 9.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG61828.1 - 1.3e-06 28.2 10.3 1.3e-06 28.2 10.3 2.0 2 0 0 2 2 1 1 zinc-RING finger domain U-box PF04564.15 GBG61828.1 - 1.5e-06 28.2 0.0 3.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.6 GBG61828.1 - 2.1e-06 27.8 5.8 1.6e-05 24.9 5.9 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING ANAPC4_WD40 PF12894.7 GBG61828.1 - 2.3e-06 27.8 0.6 8 6.8 0.1 5.5 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG61828.1 - 1.4e-05 24.6 0.4 5.1e-05 22.8 0.1 1.9 1 1 1 2 2 2 2 WD40-like domain zf-rbx1 PF12678.7 GBG61828.1 - 0.0004 20.6 6.2 0.0004 20.6 6.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GBG61828.1 - 0.0014 18.5 7.4 0.0014 18.5 7.4 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GBG61828.1 - 0.12 12.2 6.3 0.37 10.6 6.3 1.9 1 0 0 1 1 1 0 RING-like zinc finger DUF4349 PF14257.6 GBG61828.1 - 0.12 11.8 2.7 0.21 11.0 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) zf-RING_4 PF14570.6 GBG61828.1 - 0.14 11.9 8.6 0.35 10.7 8.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 GBG61828.1 - 0.17 11.7 5.8 0.77 9.6 5.7 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 GBG61828.1 - 0.98 9.6 8.8 0.2 11.8 4.6 2.1 2 0 0 2 2 1 0 zinc RING finger of MSL2 DZR PF12773.7 GBG61828.1 - 2.1 8.4 6.1 4.9 7.3 6.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 GBG61828.1 - 3.4 7.8 7.6 3.5 7.8 4.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HSP70 PF00012.20 GBG61829.1 - 5.6e-250 830.6 2.5 6.4e-250 830.5 2.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG61829.1 - 7.5e-16 57.9 1.0 8.8e-15 54.3 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 GBG61829.1 - 0.004 16.7 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 GBG61829.1 - 0.0082 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HDV_ag PF01517.18 GBG61829.1 - 0.53 10.1 4.0 34 4.2 0.0 2.6 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen Macro PF01661.21 GBG61831.1 - 9.8e-37 125.6 0.0 1.9e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Macro domain Mitofilin PF09731.9 GBG61831.1 - 0.98 8.2 6.9 1.3 7.8 6.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein rve PF00665.26 GBG61832.1 - 1.6e-12 47.6 0.0 5.9e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG61832.1 - 3.6e-11 43.0 0.8 9.7e-11 41.6 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG61832.1 - 0.0037 17.5 0.0 0.03 14.6 0.1 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein Pep_deformylase PF01327.21 GBG61832.1 - 0.074 12.6 1.9 0.16 11.6 1.9 1.4 1 0 0 1 1 1 0 Polypeptide deformylase Epimerase PF01370.21 GBG61833.1 - 2.9e-21 76.0 0.0 5.1e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GBG61833.1 - 4.2e-18 65.8 0.0 1.2e-17 64.3 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GBG61833.1 - 7.4e-05 22.0 0.0 0.0039 16.4 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_8 PF13450.6 GBG61833.1 - 0.014 15.6 2.9 4.8 7.5 0.1 3.7 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DAGK_cat PF00781.24 GBG61833.1 - 0.043 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pyr_redox_2 PF07992.14 GBG61833.1 - 0.053 12.7 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 GBG61833.1 - 0.34 10.5 1.2 0.58 9.7 0.0 2.0 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HECT PF00632.25 GBG61834.1 - 3e-93 312.7 0.0 4e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 GBG61834.1 - 0.0075 16.0 0.5 0.02 14.7 0.5 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Glyco_transf_22 PF03901.17 GBG61834.1 - 0.026 13.8 0.2 0.055 12.7 0.0 1.5 2 0 0 2 2 2 0 Alg9-like mannosyltransferase family DUF659 PF04937.15 GBG61835.1 - 3.7e-56 189.2 0.0 1.1e-33 116.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Myb_DNA-binding PF00249.31 GBG61835.1 - 2.1e-24 85.5 0.2 1.2e-10 41.4 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG61835.1 - 1.7e-16 60.2 0.2 3.7e-10 39.9 0.0 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain TFIIA PF03153.13 GBG61835.1 - 0.0043 17.1 18.0 0.0043 17.1 18.0 3.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Dimer_Tnp_hAT PF05699.14 GBG61835.1 - 0.0079 16.0 0.2 0.022 14.5 0.2 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2HE PF16278.5 GBG61835.1 - 0.11 13.0 1.4 0.37 11.3 0.3 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Suf PF05843.14 GBG61835.1 - 1 9.3 13.9 2.5 8.0 13.9 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 GBG61835.1 - 3.5 7.9 42.1 0.26 11.6 18.9 3.6 3 0 0 3 3 3 0 Anti-sigma-K factor rskA THF_DHG_CYH_C PF02882.19 GBG61836.1 - 2.2e-67 225.3 4.2 8.5e-67 223.4 1.1 2.1 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GBG61836.1 - 3.9e-43 146.4 1.0 6.1e-43 145.8 1.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 GBG61836.1 - 0.00019 20.5 0.3 0.0003 19.8 0.3 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Integrase_H2C2 PF17921.1 GBG61837.1 - 8.7e-29 99.4 2.8 3.6e-13 49.4 0.2 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG61837.1 - 1.3e-11 44.7 0.0 0.00029 21.0 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG61837.1 - 4.7e-05 23.5 0.6 0.53 10.6 0.1 2.6 2 0 0 2 2 2 2 H2C2 zinc finger Angiomotin_C PF12240.8 GBG61837.1 - 0.00062 19.4 2.4 0.51 9.9 0.2 2.6 2 0 0 2 2 2 2 Angiomotin C terminal TSSC4 PF15264.6 GBG61837.1 - 0.74 10.1 2.7 33 4.8 0.4 2.9 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 SICA_C PF12879.7 GBG61837.1 - 2.4 8.2 8.5 3.7 7.6 2.0 2.8 2 0 0 2 2 2 0 SICA C-terminal inner membrane domain A_deaminase PF00962.22 GBG61838.1 - 6.2e-121 403.7 0.0 8.5e-121 403.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase TFIIA PF03153.13 GBG61838.1 - 0.61 10.0 13.3 1 9.3 13.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4328 PF14219.6 GBG61838.1 - 5.8 6.4 6.8 4.1 6.9 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4328) zf-CCHC PF00098.23 GBG61839.1 - 3.1e-05 23.9 0.5 5.5e-05 23.0 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle HTH_37 PF13744.6 GBG61839.1 - 0.015 15.2 1.1 0.16 12.0 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain SpoIIIAH PF12685.7 GBG61839.1 - 0.4 10.5 5.0 0.58 10.0 5.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4337 PF14235.6 GBG61839.1 - 3.9 7.6 7.6 21 5.2 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Mpv17_PMP22 PF04117.12 GBG61840.1 - 1.1e-17 64.0 2.4 1.1e-17 64.0 2.4 2.4 3 0 0 3 3 3 1 Mpv17 / PMP22 family MRP-S28 PF10213.9 GBG61842.1 - 1.7e-17 64.0 0.0 2.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein NifQ PF04891.12 GBG61842.1 - 0.2 12.0 0.3 1.1 9.6 0.1 1.9 2 0 0 2 2 2 0 NifQ DBD_Tnp_Mut PF03108.15 GBG61843.1 - 0.076 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 MuDR family transposase RT_RNaseH PF17917.1 GBG61845.1 - 8.7e-23 80.6 0.0 1.6e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61845.1 - 5.6e-20 71.2 0.0 1.2e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase KRE1 PF17056.5 GBG61846.1 - 0.02 14.6 0.1 0.06 13.1 0.1 1.8 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 DUF659 PF04937.15 GBG61848.1 - 4.9e-15 55.7 0.0 7.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61848.1 - 0.021 14.6 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG61849.1 - 1.1e-17 64.3 0.0 2.5e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61849.1 - 3e-05 23.7 0.0 7.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Gp_dh_C PF02800.20 GBG61851.1 - 1.3e-70 236.1 0.0 1.9e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG61851.1 - 6.8e-40 135.5 0.1 1.9e-39 134.1 0.1 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GBG61851.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 GBG61852.1 - 1e-38 131.7 0.1 2.1e-38 130.7 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 GBG61852.1 - 3e-13 49.7 0.0 4.9e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 GBG61852.1 - 0.044 13.2 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RVT_1 PF00078.27 GBG61855.1 - 7.9e-33 113.8 0.0 2e-32 112.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) LTV PF04180.14 GBG61856.1 - 3.3e-19 69.9 17.4 1.2e-16 61.5 5.1 4.5 3 1 0 3 3 3 2 Low temperature viability protein Glyoxalase PF00903.25 GBG61857.1 - 3.2e-14 53.2 0.0 8.7e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 GBG61857.1 - 1.7e-07 31.2 0.1 3.8e-07 30.0 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 GBG61857.1 - 4e-06 27.6 0.0 6.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 GBG61857.1 - 0.00085 19.6 0.0 0.002 18.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 GBG61857.1 - 0.22 11.6 0.0 9.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain RVT_1 PF00078.27 GBG61858.1 - 9.6e-26 90.7 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG61858.1 - 0.00076 19.7 0.1 0.0057 16.9 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein FAT PF02259.23 GBG61858.1 - 0.14 11.3 0.0 0.32 10.1 0.0 1.5 2 0 0 2 2 2 0 FAT domain zf-C2H2_2 PF12756.7 GBG61858.1 - 0.15 12.5 0.0 3.6 8.0 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) E1_dh PF00676.20 GBG61860.1 - 3.9e-48 163.9 0.0 6.5e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 GBG61860.1 - 2.7e-41 141.2 0.2 5e-40 137.1 0.0 2.7 2 1 0 2 2 2 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 GBG61860.1 - 1.6e-19 70.1 0.0 3.7e-13 49.4 0.1 2.5 1 1 1 2 2 2 2 2-oxoglutarate dehydrogenase C-terminal EF-hand_7 PF13499.6 GBG61860.1 - 0.00052 20.4 0.1 0.0011 19.4 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GBG61860.1 - 0.0015 18.0 0.1 0.043 13.4 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GBG61860.1 - 0.069 13.1 0.1 0.35 10.9 0.1 2.2 3 0 0 3 3 3 0 EF-hand domain R2K_2 PF18299.1 GBG61860.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 tRNA-synt_2b PF00587.25 GBG61861.1 - 2.1e-38 132.1 0.0 2.6e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Nucleocap_ssRNA PF11128.8 GBG61861.1 - 0.018 14.8 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Plant viral coat protein nucleocapsid UCR_14kD PF02271.16 GBG61862.1 - 0.074 13.0 0.2 5 7.2 0.0 3.0 4 0 0 4 4 4 0 Ubiquinol-cytochrome C reductase complex 14kD subunit CENP-I PF07778.11 GBG61862.1 - 0.082 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Mis6 zf-CCHC PF00098.23 GBG61864.1 - 0.052 13.7 1.3 0.11 12.7 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF5621 PF18532.1 GBG61864.1 - 0.19 11.6 1.5 0.98 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5621) RT_RNaseH_2 PF17919.1 GBG61866.1 - 1.8e-30 104.9 0.0 3.7e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61866.1 - 8.6e-27 93.5 0.2 2e-26 92.3 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61866.1 - 4.8e-12 45.9 0.2 1e-11 44.8 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG61866.1 - 0.046 13.7 2.1 0.1 12.6 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.11 GBG61866.1 - 0.86 7.8 3.5 1.8 6.8 3.5 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-CCHC PF00098.23 GBG61866.1 - 3.5 7.9 4.9 6.6 7.0 4.9 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG61867.1 - 1.8e-30 104.9 0.0 3.6e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61867.1 - 8.4e-27 93.5 0.2 1.9e-26 92.3 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61867.1 - 4.8e-12 45.9 0.2 1e-11 44.8 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG61867.1 - 0.045 13.7 2.1 0.1 12.6 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.11 GBG61867.1 - 0.84 7.8 3.5 1.7 6.8 3.5 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-CCHC PF00098.23 GBG61867.1 - 3.4 7.9 4.9 6.5 7.0 4.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_6 PF12697.7 GBG61868.1 - 8.5e-21 75.6 0.7 5.4e-20 72.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG61868.1 - 1.3e-12 47.5 0.0 4.2e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG61868.1 - 8.7e-12 45.2 0.3 1.1e-08 35.1 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Yip1 PF04893.17 GBG61870.1 - 5.7e-14 52.2 13.8 8.4e-14 51.7 13.8 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1624 PF07786.12 GBG61870.1 - 0.094 12.3 6.0 0.13 11.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Trp_oprn_chp PF09534.10 GBG61870.1 - 1.1 9.1 6.7 2.3 8.0 0.6 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SDA1 PF05285.12 GBG61872.1 - 6.7e-61 206.6 93.2 2.3e-58 198.3 88.3 3.2 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 GBG61872.1 - 4.2e-20 71.8 0.5 1e-19 70.5 0.5 1.7 1 0 0 1 1 1 1 NUC130/3NT domain Ank_2 PF12796.7 GBG61873.1 - 4.8e-37 126.4 0.0 4.6e-14 52.8 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GBG61873.1 - 2.1e-35 120.3 1.1 3.9e-10 39.8 0.6 7.0 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 GBG61873.1 - 1.9e-34 117.5 0.0 1.1e-09 38.6 0.0 6.8 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG61873.1 - 2.6e-25 85.7 0.1 0.00019 21.6 0.0 8.8 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 GBG61873.1 - 1.9e-23 81.8 0.0 7e-06 26.3 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat DUF659 PF04937.15 GBG61873.1 - 8.1e-20 71.2 0.0 1.4e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61873.1 - 5.9e-07 29.2 0.1 1.2e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG61874.1 - 2.7e-26 91.5 0.0 4.6e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61874.1 - 4.3e-23 81.6 0.0 7.1e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61874.1 - 1.7e-12 47.3 0.1 2.3e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG61874.1 - 1.5 6.9 22.1 1.9 6.6 22.1 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 GBG61874.1 - 1.9 8.7 13.8 3.4 7.9 13.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG61874.1 - 2.2 7.6 23.5 3.1 7.1 23.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG61874.1 - 2.4 6.3 14.7 3.7 5.7 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG61874.1 - 6 6.1 22.5 8.5 5.6 22.5 1.2 1 0 0 1 1 1 0 BUD22 bZIP_1 PF00170.21 GBG61875.1 - 1.5e-09 37.8 13.5 1.5e-09 37.8 13.5 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GBG61875.1 - 4.9e-07 29.7 21.8 1.1e-06 28.6 13.2 2.4 1 1 1 2 2 2 1 Basic region leucine zipper Rootletin PF15035.6 GBG61875.1 - 0.0017 18.4 3.8 0.0038 17.3 3.8 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion bZIP_Maf PF03131.17 GBG61875.1 - 0.0022 18.5 13.4 0.003 18.0 12.1 1.9 1 1 0 1 1 1 1 bZIP Maf transcription factor YabA PF06156.13 GBG61875.1 - 0.11 13.2 4.4 0.34 11.6 4.4 1.9 1 1 0 1 1 1 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 GBG61875.1 - 0.11 12.6 13.0 0.24 11.5 13.0 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 GBG61875.1 - 0.41 9.5 5.4 0.63 8.9 5.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Leu_zip PF15294.6 GBG61875.1 - 0.43 10.0 6.6 0.67 9.4 6.6 1.2 1 0 0 1 1 1 0 Leucine zipper ZapB PF06005.12 GBG61875.1 - 0.62 10.5 8.2 1.2 9.6 7.7 1.8 1 1 0 1 1 1 0 Cell division protein ZapB UPF0242 PF06785.11 GBG61875.1 - 0.9 9.6 5.7 1.6 8.8 5.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 GBG61875.1 - 1.7 8.9 4.5 2.3 8.5 1.0 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper Dimer_Tnp_hAT PF05699.14 GBG61877.1 - 8.9e-07 28.6 0.1 1.6e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TRP PF06011.12 GBG61878.1 - 2.5e-09 36.4 9.0 2.8e-08 32.9 0.3 2.3 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel AP3D1 PF06375.11 GBG61878.1 - 0.0033 17.7 6.1 0.0075 16.5 6.1 1.5 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 DUF2207 PF09972.9 GBG61878.1 - 0.0048 15.7 0.0 0.079 11.7 0.0 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) Ferric_reduct PF01794.19 GBG61878.1 - 0.024 14.7 2.4 0.059 13.5 2.4 1.6 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Rib_recp_KP_reg PF05104.12 GBG61878.1 - 0.074 14.1 10.1 0.31 12.1 10.1 2.0 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region RNA_polI_A34 PF08208.11 GBG61878.1 - 0.17 11.9 12.5 2.2 8.3 12.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 NARP1 PF12569.8 GBG61878.1 - 0.26 10.1 3.8 1.6 7.5 5.0 1.6 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 OAD_gamma PF04277.13 GBG61878.1 - 0.59 10.8 4.0 2.9 8.6 4.0 2.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain FAM176 PF14851.6 GBG61878.1 - 2.2 8.0 3.9 0.99 9.1 0.3 2.2 2 0 0 2 2 2 0 FAM176 family Rabaptin PF03528.15 GBG61878.1 - 2.2 6.9 6.7 3.4 6.3 6.7 1.2 1 0 0 1 1 1 0 Rabaptin STAG PF08514.11 GBG61878.1 - 8.5 6.3 6.5 23 4.9 5.0 2.2 2 0 0 2 2 2 0 STAG domain TRP PF06011.12 GBG61879.1 - 6.6e-08 31.7 7.7 1.9e-06 26.9 0.1 2.2 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel Ferric_reduct PF01794.19 GBG61879.1 - 0.017 15.3 2.4 0.041 14.0 2.4 1.6 1 0 0 1 1 1 0 Ferric reductase like transmembrane component DUF2207 PF09972.9 GBG61879.1 - 0.024 13.4 0.0 0.052 12.3 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-CCHC PF00098.23 GBG61883.1 - 4.1e-08 32.9 7.2 9.3e-08 31.8 7.2 1.7 1 0 0 1 1 1 1 Zinc knuckle JmjC PF02373.22 GBG61883.1 - 0.15 12.5 1.2 0.32 11.4 0.0 2.1 2 1 1 3 3 3 0 JmjC domain, hydroxylase zf-CCHC_6 PF15288.6 GBG61883.1 - 0.15 11.9 2.4 0.51 10.2 2.4 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG61883.1 - 0.26 11.0 1.7 0.65 9.8 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle ARD PF03079.14 GBG61883.1 - 7.8 6.7 7.7 22 5.2 7.7 1.8 1 0 0 1 1 1 0 ARD/ARD' family RRM_2 PF04059.12 GBG61886.1 - 2.1e-54 181.7 0.6 3.4e-54 181.0 0.6 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 GBG61886.1 - 1.8e-27 94.9 0.7 5.1e-12 45.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG61886.1 - 8.2e-08 32.0 0.0 0.01 15.7 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GBG61886.1 - 8.4e-08 31.9 0.0 0.00016 21.2 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 GBG61886.1 - 0.038 14.0 0.1 0.038 14.0 0.1 1.7 2 0 0 2 2 2 0 Smg-4/UPF3 family DUF533 PF04391.12 GBG61886.1 - 0.43 10.1 3.3 0.16 11.5 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF533) RRM_2 PF04059.12 GBG61887.1 - 2.1e-54 181.7 0.6 3.4e-54 181.0 0.6 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 GBG61887.1 - 1.8e-27 94.9 0.7 5.1e-12 45.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG61887.1 - 8.2e-08 32.0 0.0 0.01 15.7 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GBG61887.1 - 8.4e-08 31.9 0.0 0.00016 21.2 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 GBG61887.1 - 0.038 14.0 0.1 0.038 14.0 0.1 1.7 2 0 0 2 2 2 0 Smg-4/UPF3 family DUF533 PF04391.12 GBG61887.1 - 0.42 10.1 3.3 0.16 11.5 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF533) rve PF00665.26 GBG61889.1 - 2.8e-11 43.7 0.0 5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain NPR3 PF03666.13 GBG61892.1 - 0.00091 18.1 9.4 0.00091 18.1 9.4 2.2 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Utp14 PF04615.13 GBG61892.1 - 0.78 8.2 27.8 1 7.9 27.8 1.0 1 0 0 1 1 1 0 Utp14 protein Presenilin PF01080.17 GBG61892.1 - 3.2 6.4 26.3 0.067 12.0 15.3 2.0 2 0 0 2 2 2 0 Presenilin FAM60A PF15396.6 GBG61892.1 - 7 6.6 15.6 3.6 7.5 10.0 2.1 2 0 0 2 2 2 0 Protein Family FAM60A CHCH PF06747.13 GBG61893.1 - 1.5e-08 34.6 3.2 1.9e-08 34.2 3.2 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 GBG61893.1 - 0.00017 21.5 1.1 0.00023 21.1 1.1 1.1 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 GBG61893.1 - 0.0002 21.5 1.4 0.00027 21.1 1.4 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 GBG61893.1 - 0.031 14.6 0.9 0.044 14.1 0.9 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 GBG61893.1 - 0.14 12.1 0.9 2.5 8.2 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2076 PF09849.9 GBG61893.1 - 0.72 9.8 3.4 0.85 9.6 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RVT_1 PF00078.27 GBG61895.1 - 5.6e-30 104.5 0.1 9.5e-30 103.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61895.1 - 8.8e-27 93.1 0.0 1.4e-12 47.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61895.1 - 2.4e-26 92.0 0.0 5.1e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 GBG61895.1 - 0.2 11.5 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.27 GBG61896.1 - 6.4e-30 104.3 0.1 1.1e-29 103.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61896.1 - 1.2e-29 102.3 0.0 1.6e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61896.1 - 5.7e-28 97.3 0.0 1.2e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61896.1 - 9.4e-05 22.4 0.2 9.4e-05 22.4 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain DUF3824 PF12868.7 GBG61896.1 - 1.2 9.7 11.9 2.5 8.8 11.9 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) RVT_1 PF00078.27 GBG61897.1 - 1e-101 339.1 7.2 6.2e-29 101.1 0.1 4.5 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61897.1 - 5.3e-50 167.6 0.0 5.6e-28 96.9 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61897.1 - 1.6e-35 121.6 0.0 7.2e-24 84.1 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61897.1 - 2.5e-24 85.7 0.0 3.8e-12 46.5 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain gag-asp_proteas PF13975.6 GBG61897.1 - 5.4e-11 42.9 0.0 0.00038 21.0 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61897.1 - 2.1e-08 34.7 0.0 0.00071 20.2 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG61897.1 - 2.7e-07 30.4 0.0 0.0004 20.2 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 GBG61897.1 - 0.00013 21.7 0.0 0.41 10.4 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease EF-hand_6 PF13405.6 GBG61897.1 - 0.0043 16.9 0.1 0.018 14.9 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain rve_3 PF13683.6 GBG61897.1 - 0.016 14.9 0.0 2.2 8.1 0.0 3.2 2 0 0 2 2 2 0 Integrase core domain EF-hand_1 PF00036.32 GBG61897.1 - 0.043 13.4 0.1 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 EF hand RT_RNaseH_2 PF17919.1 GBG61898.1 - 1.5e-32 111.5 0.3 4.7e-32 110.0 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61898.1 - 1.7e-28 98.9 0.2 4.8e-28 97.5 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61898.1 - 1.4e-10 41.1 0.0 2.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG61898.1 - 4.5e-07 30.4 0.2 4.8e-06 27.0 0.0 2.7 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG61898.1 - 0.00021 21.0 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61898.1 - 0.0019 18.8 0.0 0.0086 16.7 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG61898.1 - 0.0023 17.7 0.1 0.0064 16.3 0.0 1.8 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 GBG61898.1 - 0.023 14.8 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain Apc13p PF05839.11 GBG61898.1 - 0.19 11.9 1.1 0.58 10.4 1.1 1.8 1 0 0 1 1 1 0 Apc13p protein Miga PF10265.9 GBG61898.1 - 1.3 7.9 9.1 2.2 7.2 9.1 1.3 1 0 0 1 1 1 0 Mitoguardin Antimicrobial_9 PF08104.11 GBG61899.1 - 0.1 12.6 0.1 18 5.5 0.1 2.5 2 0 0 2 2 2 0 Ponericin L family Presenilin PF01080.17 GBG61899.1 - 5.1 5.8 4.9 5.9 5.5 4.2 1.4 2 0 0 2 2 2 0 Presenilin RVT_1 PF00078.27 GBG61900.1 - 1.2e-21 77.2 0.1 1.9e-21 76.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG61900.1 - 6.5e-11 42.0 0.0 1.2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG61901.1 - 9e-63 211.8 3.1 4.5e-30 104.8 0.1 4.4 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61901.1 - 3.8e-26 91.4 0.0 1e-25 90.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61901.1 - 3e-25 88.2 0.0 7.9e-25 86.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61901.1 - 3.3e-08 33.5 0.0 9.1e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG61901.1 - 1.3e-07 32.2 0.0 0.00035 21.2 0.0 3.6 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61901.1 - 2.3e-06 28.0 0.0 0.085 13.4 0.0 3.6 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG61901.1 - 0.00014 21.6 0.0 0.00055 19.7 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG61901.1 - 0.027 14.3 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG61901.1 - 0.12 12.2 0.0 3.1 7.6 0.0 2.6 2 1 0 2 2 2 0 Aspartyl protease FapA PF03961.13 GBG61901.1 - 0.81 8.2 2.5 1.8 7.0 2.5 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 GBG61901.1 - 2.3 8.2 4.2 7.7 6.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PGBA_C PF15437.6 GBG61901.1 - 4 7.9 17.4 14 6.1 17.4 1.9 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal RVT_1 PF00078.27 GBG61902.1 - 1.2e-33 116.5 0.5 2.4e-33 115.5 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2203 PF09969.9 GBG61902.1 - 0.12 13.1 2.1 0.44 11.3 2.1 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1690 PF07956.11 GBG61903.1 - 5.4 7.4 19.6 0.44 11.0 3.2 2.6 2 2 0 2 2 2 0 Protein of Unknown function (DUF1690) RVT_1 PF00078.27 GBG61904.1 - 4.1e-26 91.9 0.1 6.1e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG61904.1 - 5.3e-07 30.2 0.0 1.2e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61904.1 - 5.3e-07 30.1 0.0 9.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG61904.1 - 3.2e-06 26.9 0.0 5.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG61904.1 - 0.00014 21.6 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG61905.1 - 2.4e-30 105.7 0.0 4.2e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61905.1 - 1.5e-11 44.5 0.0 4e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG61907.1 - 0.0034 17.6 0.2 0.086 13.1 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Peptidase_S64 PF08192.11 GBG61907.1 - 0.1 11.1 1.8 0.15 10.5 1.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Miga PF10265.9 GBG61907.1 - 0.89 8.5 4.6 1.3 7.9 4.6 1.2 1 0 0 1 1 1 0 Mitoguardin RAP1 PF07218.11 GBG61907.1 - 3.1 5.9 5.9 4.7 5.4 5.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Integrase_H2C2 PF17921.1 GBG61908.1 - 4.2e-19 68.4 3.4 1.6e-18 66.6 0.6 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG61908.1 - 3.8e-12 46.4 2.2 1e-11 45.1 0.2 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61908.1 - 0.00018 21.5 0.0 0.00053 20.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HIP1_clath_bdg PF16515.5 GBG61908.1 - 0.012 16.2 1.6 0.012 16.2 1.6 3.0 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-C2H2_2 PF12756.7 GBG61908.1 - 0.094 13.1 0.1 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) BLOC1_2 PF10046.9 GBG61908.1 - 0.12 12.7 2.9 0.5 10.7 1.7 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GBG61908.1 - 0.21 12.1 0.8 2 8.9 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CBP4 PF07960.11 GBG61908.1 - 0.37 10.7 2.4 0.52 10.2 1.5 1.7 1 1 0 1 1 1 0 CBP4 DUF4407 PF14362.6 GBG61908.1 - 1.1 8.6 13.4 2.7 7.3 9.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Adaptin_binding PF10199.9 GBG61908.1 - 1.6 9.3 9.0 3.9 8.1 8.2 1.9 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RT_RNaseH PF17917.1 GBG61909.1 - 1.9e-39 134.1 2.7 4.4e-24 84.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61909.1 - 3e-35 120.2 0.1 9.3e-28 96.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61909.1 - 7.6e-28 97.5 0.1 1.5e-27 96.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG61909.1 - 1.6e-09 37.7 0.1 4.7e-09 36.2 0.1 1.9 2 0 0 2 2 1 1 Integrase zinc binding domain rve PF00665.26 GBG61909.1 - 3.2e-09 37.0 0.0 1.1e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain LRR_6 PF13516.6 GBG61909.1 - 6.8e-06 25.7 0.3 0.12 12.5 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeat STI1 PF17830.1 GBG61909.1 - 0.00042 20.2 0.9 0.77 9.7 0.1 2.7 2 0 0 2 2 2 2 STI1 domain Rhamno_transf PF11316.8 GBG61909.1 - 0.0039 16.6 0.3 0.29 10.5 0.1 2.6 2 0 0 2 2 2 1 Putative rhamnosyl transferase Chromo PF00385.24 GBG61909.1 - 0.043 13.7 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain SH3_16 PF18348.1 GBG61909.1 - 0.076 12.8 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain EIAV_Rev PF11129.8 GBG61909.1 - 0.31 11.2 1.9 0.85 9.8 1.9 1.7 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus Ribosomal_S27 PF01599.19 GBG61910.1 - 0.018 15.2 0.1 1.6 9.0 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein S27a ParD_antitoxin PF03693.14 GBG61910.1 - 0.11 12.9 0.6 0.4 11.1 0.6 2.0 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH MCC-bdg_PDZ PF10506.9 GBG61910.1 - 0.16 12.0 1.9 0.33 11.0 0.1 2.5 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ADK_lid PF05191.14 GBG61910.1 - 0.41 10.7 3.0 0.53 10.3 1.5 2.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid 14-3-3 PF00244.20 GBG61911.1 - 1.9e-59 200.8 1.7 3.3e-54 183.7 0.1 2.2 1 1 1 2 2 2 2 14-3-3 protein LRR_6 PF13516.6 GBG61911.1 - 5.9e-13 47.7 5.6 0.0025 17.7 0.0 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 GBG61911.1 - 0.021 14.6 0.3 1.1 9.0 0.0 2.8 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 GBG61911.1 - 0.026 15.0 2.0 73 4.5 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 GBG61911.1 - 0.085 13.3 0.9 2.1 8.9 0.0 3.1 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) PPP4R2 PF09184.11 GBG61911.1 - 4.4 6.8 6.2 8.4 5.9 6.2 1.5 1 0 0 1 1 1 0 PPP4R2 rve PF00665.26 GBG61912.1 - 4.7e-14 52.6 0.0 8.4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG61913.1 - 5.4e-34 116.2 0.0 1.1e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61913.1 - 9.4e-32 110.3 0.1 1.7e-31 109.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61913.1 - 6.5e-31 106.7 0.0 1.4e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61913.1 - 2e-19 69.4 0.1 4.5e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61913.1 - 1.9e-05 24.9 0.1 0.18 12.0 0.0 2.9 1 1 1 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG61913.1 - 0.034 14.4 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger DUF1564 PF07600.11 GBG61913.1 - 0.078 12.7 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DUF659 PF04937.15 GBG61914.1 - 1.3e-38 132.3 0.0 3.2e-38 131.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61914.1 - 0.0011 18.7 0.0 0.004 16.9 0.0 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG61915.1 - 4.6e-05 23.3 0.0 6.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Atrophin-1 PF03154.15 GBG61915.1 - 0.12 10.7 1.3 0.17 10.1 1.3 1.2 1 0 0 1 1 1 0 Atrophin-1 family RT_RNaseH_2 PF17919.1 GBG61916.1 - 2.9e-23 81.8 0.0 6e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61916.1 - 6.3e-22 77.9 0.0 4.8e-21 75.0 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61916.1 - 6e-13 49.0 0.0 2.7e-12 46.9 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG61916.1 - 2.3e-11 43.6 0.1 8.5e-11 41.8 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG61916.1 - 0.0026 18.3 0.0 0.016 15.8 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61916.1 - 0.003 18.2 0.1 0.022 15.4 0.0 2.5 3 0 0 3 3 3 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG61916.1 - 0.012 15.4 0.6 0.031 14.1 0.6 1.8 1 0 0 1 1 1 0 Zinc knuckle HTH_29 PF13551.6 GBG61916.1 - 0.044 13.8 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn helix RVP PF00077.20 GBG61916.1 - 0.068 13.5 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG61917.1 - 1e-34 118.6 0.1 7.6e-34 115.7 0.1 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61917.1 - 2.8e-32 111.1 0.2 1.7e-30 105.4 0.1 3.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61917.1 - 5e-19 68.2 0.2 1.4e-18 66.8 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG61917.1 - 3.5e-17 62.7 0.0 7.7e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG61917.1 - 6.9e-08 32.7 0.0 2.4e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61917.1 - 0.019 15.2 0.5 0.12 12.6 0.0 2.7 3 0 0 3 3 3 0 H2C2 zinc finger PhoU PF01895.19 GBG61917.1 - 0.75 10.3 4.9 0.34 11.4 1.0 2.3 2 0 0 2 2 2 0 PhoU domain Caldesmon PF02029.15 GBG61917.1 - 1.3 7.7 13.5 2.1 7.0 13.5 1.3 1 0 0 1 1 1 0 Caldesmon Asp_protease_2 PF13650.6 GBG61918.1 - 6.7e-09 36.3 0.1 2.2e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61918.1 - 2.4e-08 34.4 0.0 6.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG61918.1 - 4.3e-06 26.5 0.0 7.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG61918.1 - 2.1e-05 24.3 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DUF4681 PF15732.5 GBG61918.1 - 1.8 8.8 4.2 3 8.1 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) RVT_1 PF00078.27 GBG61919.1 - 4.8e-23 81.8 0.1 6.8e-21 74.8 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 GBG61919.1 - 0.0002 21.5 0.0 0.0002 21.5 0.0 2.4 2 0 0 2 2 2 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG61919.1 - 0.00061 19.7 1.2 0.0016 18.4 1.2 1.8 1 0 0 1 1 1 1 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG61921.1 - 3.8e-28 98.2 0.0 4.4e-27 94.7 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease rve PF00665.26 GBG61921.1 - 4.4e-16 59.1 0.0 1.5e-15 57.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Plant_tran PF04827.14 GBG61921.1 - 5.1e-13 49.1 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG61921.1 - 1.9e-07 30.9 0.8 0.00081 19.1 0.0 3.7 3 0 0 3 3 3 2 Transposase DDE domain RVP_2 PF08284.11 GBG61921.1 - 1.1e-06 28.4 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG61921.1 - 0.00011 22.7 0.0 0.00026 21.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG61921.1 - 0.00019 21.2 0.0 0.00047 19.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61921.1 - 0.00065 20.2 0.0 0.0018 18.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease CCD48 PF15799.5 GBG61921.1 - 0.016 13.6 1.1 0.027 12.8 1.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 eIF-1a PF01176.19 GBG61921.1 - 0.057 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 bZIP_2 PF07716.15 GBG61921.1 - 0.14 12.3 2.2 0.46 10.6 2.2 1.9 1 0 0 1 1 1 0 Basic region leucine zipper Retrotrans_gag PF03732.17 GBG61922.1 - 0.025 14.9 0.2 0.025 14.9 0.2 3.6 4 0 0 4 4 4 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 GBG61923.1 - 0.01 16.1 0.2 0.01 16.1 0.2 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein YL1 PF05764.13 GBG61924.1 - 0.013 15.6 4.5 0.024 14.8 4.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GBG61924.1 - 0.035 13.8 1.2 0.053 13.2 1.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG61924.1 - 1.7 6.7 5.9 2.2 6.4 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG61924.1 - 1.9 6.7 5.5 2.6 6.2 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG61925.1 - 4.3e-16 59.1 0.0 6.8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG61926.1 - 3.2e-06 27.4 3.2 6.4e-06 26.5 3.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain UBA_5 PF16577.5 GBG61928.1 - 3.3 7.9 4.5 31 4.8 4.5 2.4 1 1 0 1 1 1 0 UBA domain Bac_surface_Ag PF01103.23 GBG61930.1 - 5.4e-12 45.9 0.2 8.2e-12 45.3 0.2 1.2 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 GBG61930.1 - 3.8e-11 43.4 2.0 0.012 16.2 0.0 4.0 4 0 0 4 4 4 3 Surface antigen variable number repeat POTRA_2 PF08479.11 GBG61930.1 - 0.0052 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 POTRA domain, ShlB-type Sigma70_ner PF04546.13 GBG61930.1 - 0.16 11.9 0.7 0.3 11.0 0.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PA26 PF04636.13 GBG61931.1 - 0.12 11.3 4.1 0.16 10.8 4.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Connexin PF00029.19 GBG61931.1 - 0.22 11.3 1.8 0.35 10.6 1.8 1.3 1 0 0 1 1 1 0 Connexin DUF3138 PF11336.8 GBG61931.1 - 0.54 8.8 3.1 0.73 8.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2950 PF11453.8 GBG61931.1 - 0.57 9.3 8.1 0.81 8.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) DUF2681 PF10883.8 GBG61931.1 - 2.1 8.8 8.5 4.6 7.7 8.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CDC45 PF02724.14 GBG61932.1 - 4 5.6 37.1 4.6 5.4 37.1 1.0 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.7 GBG61934.1 - 1.2e-05 25.1 1.0 0.00046 20.0 0.5 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 GBG61934.1 - 0.00021 21.0 1.4 0.018 14.9 1.2 2.8 2 0 0 2 2 2 1 F-box domain PNMA PF14893.6 GBG61934.1 - 0.015 14.7 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 PNMA DDE_Tnp_4 PF13359.6 GBG61936.1 - 1e-18 67.5 0.0 1.8e-17 63.5 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG61936.1 - 1.2e-08 34.8 0.0 2.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein AdoMet_MTase PF07757.13 GBG61936.1 - 0.012 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase UcrQ PF02939.16 GBG61936.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 UcrQ family RT_RNaseH_2 PF17919.1 GBG61937.1 - 1.1e-25 89.5 0.0 2.9e-25 88.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61937.1 - 2.1e-22 79.4 0.3 6.8e-22 77.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61937.1 - 1.3e-17 64.0 0.1 5.8e-17 62.0 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG61937.1 - 0.0016 18.7 4.5 0.0048 17.2 0.1 3.9 4 0 0 4 4 4 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG61937.1 - 0.025 14.3 1.9 0.096 12.5 1.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG61937.1 - 0.32 10.3 9.3 0.74 9.1 9.3 1.6 1 0 0 1 1 1 0 FAM76 protein Vfa1 PF08432.10 GBG61937.1 - 2.1 8.6 8.6 5.1 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 P4Ha_N PF08336.11 GBG61937.1 - 8.2 6.4 7.7 5.3 7.1 0.0 3.4 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PspB PF06667.12 GBG61937.1 - 9.2 6.4 7.9 40 4.4 0.2 2.8 2 0 0 2 2 2 0 Phage shock protein B DUF659 PF04937.15 GBG61939.1 - 3.1e-26 92.1 0.0 5.4e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cwf_Cwc_15 PF04889.12 GBG61940.1 - 0.00082 19.2 19.0 0.0018 18.1 19.0 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG61940.1 - 0.0013 17.1 7.8 0.0015 17.0 7.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG61940.1 - 0.47 8.6 25.5 0.066 11.4 21.4 1.5 2 0 0 2 2 2 0 Nop14-like family PPP4R2 PF09184.11 GBG61940.1 - 0.54 9.8 18.6 0.88 9.1 18.6 1.4 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 GBG61940.1 - 0.61 9.5 25.2 0.92 8.9 25.2 1.2 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.8 GBG61940.1 - 1.3 7.9 14.1 2.1 7.2 14.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CNDH2_C PF16858.5 GBG61940.1 - 1.6 8.5 11.5 0.26 11.1 7.4 1.7 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_pol_phi PF04931.13 GBG61940.1 - 8.4 4.3 36.9 12 3.9 36.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_M41 PF01434.18 GBG61942.1 - 4.6e-34 117.9 0.0 6.8e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GBG61942.1 - 2.5e-25 89.4 0.1 7.9e-25 87.8 0.1 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG61942.1 - 2.1e-11 43.4 0.1 5e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Exo_endo_phos_2 PF14529.6 GBG61944.1 - 0.0085 15.9 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase FtsH_ext PF06480.15 GBG61944.1 - 0.023 15.0 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsH Extracellular Retrotrans_gag PF03732.17 GBG61946.1 - 0.00091 19.5 1.2 0.0023 18.2 0.2 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG61947.1 - 4.7e-25 88.4 0.0 7.1e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG61948.1 - 1.5e-88 296.0 3.3 2.5e-34 118.7 0.1 3.4 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) DUF639 PF04842.12 GBG61948.1 - 4.2e-51 173.6 3.7 7.7e-51 172.7 3.7 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) RT_RNaseH_2 PF17919.1 GBG61948.1 - 2.9e-33 113.9 0.0 1.1e-19 70.3 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG61948.1 - 1.7e-18 66.7 0.0 3.5e-06 26.8 0.0 3.6 3 0 0 3 3 3 3 Retroviral aspartyl protease rve PF00665.26 GBG61948.1 - 1.8e-14 53.9 0.0 5.2e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG61948.1 - 4.8e-13 49.6 0.1 0.00088 19.9 0.0 5.0 4 0 0 4 4 4 3 Aspartyl protease gag-asp_proteas PF13975.6 GBG61948.1 - 2.6e-12 47.1 0.0 0.0064 17.0 0.0 4.2 3 0 0 3 3 3 3 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG61948.1 - 1.5e-10 41.2 0.0 1.2e-06 28.7 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG61948.1 - 3.9e-08 33.1 0.0 0.0045 16.8 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease DUF1758 PF05585.12 GBG61948.1 - 7.3e-06 25.8 0.0 0.16 11.7 0.0 2.6 2 0 0 2 2 2 2 Putative peptidase (DUF1758) CCDC85 PF10226.9 GBG61948.1 - 0.1 12.3 0.5 0.35 10.5 0.5 1.9 1 0 0 1 1 1 0 CCDC85 family Biotin_carb_C PF02785.19 GBG61948.1 - 0.1 12.7 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 Biotin carboxylase C-terminal domain Phage_holin_3_6 PF07332.11 GBG61948.1 - 0.13 12.3 1.4 13 5.8 0.1 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III bZIP_2 PF07716.15 GBG61948.1 - 1.2 9.2 3.5 4.7 7.4 3.5 2.1 1 0 0 1 1 1 0 Basic region leucine zipper SelK_SelG PF10961.8 GBG61949.1 - 0.0013 19.3 0.0 0.0014 19.2 0.0 1.1 1 0 0 1 1 1 1 Selenoprotein SelK_SelG DUF287 PF03384.14 GBG61950.1 - 0.054 13.9 1.0 0.13 12.7 1.0 1.7 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 Retrotrans_gag PF03732.17 GBG61951.1 - 0.01 16.1 0.8 0.052 13.8 0.0 2.5 3 0 0 3 3 3 0 Retrotransposon gag protein DUF3729 PF12526.8 GBG61951.1 - 0.61 11.7 8.5 1.6 10.3 7.9 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3729) HAUS6_N PF14661.6 GBG61951.1 - 1.9 8.0 5.6 0.65 9.5 2.5 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus B3 PF02362.21 GBG61952.1 - 6.6e-15 54.8 0.8 1.5e-07 31.2 0.1 3.1 2 0 0 2 2 2 2 B3 DNA binding domain RVT_1 PF00078.27 GBG61953.1 - 2.2e-15 56.8 0.0 3.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_NinH PF06322.11 GBG61953.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage NinH protein Integrase_H2C2 PF17921.1 GBG61954.1 - 4.7e-12 45.8 0.4 1.1e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain Alpha_Helical PF18489.1 GBG61954.1 - 0.13 12.4 0.0 0.74 10.0 0.0 2.2 2 0 0 2 2 2 0 Alpha helical domain Rrn6 PF10214.9 GBG61954.1 - 0.16 10.4 11.8 0.063 11.8 9.2 1.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor ABC_tran_CTD PF16326.5 GBG61955.1 - 0.0021 18.3 3.6 0.51 10.6 0.9 2.6 2 0 0 2 2 2 2 ABC transporter C-terminal domain CCD48 PF15799.5 GBG61955.1 - 0.0041 15.5 1.9 0.0066 14.8 1.9 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 ZapB PF06005.12 GBG61955.1 - 0.028 14.8 7.4 0.48 10.9 2.4 2.4 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 GBG61955.1 - 0.042 14.5 0.0 0.84 10.3 0.0 2.4 2 0 0 2 2 2 0 Initiation control protein YabA CCDC85 PF10226.9 GBG61955.1 - 0.044 13.5 0.5 0.088 12.5 0.0 1.7 2 0 0 2 2 2 0 CCDC85 family HALZ PF02183.18 GBG61955.1 - 0.048 13.9 1.1 0.17 12.2 1.1 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper Swi5 PF07061.11 GBG61955.1 - 0.13 12.3 1.4 7.3 6.7 0.1 2.5 2 0 0 2 2 2 0 Swi5 bZIP_2 PF07716.15 GBG61955.1 - 0.25 11.5 5.9 0.14 12.2 2.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 GBG61955.1 - 0.57 10.0 5.4 0.25 11.1 1.3 2.2 2 0 0 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 GBG61955.1 - 1.4 9.1 7.6 4.3 7.5 0.1 2.7 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 GBG61955.1 - 2.3 8.3 6.7 0.69 10.0 1.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 GBG61955.1 - 5.1 7.3 7.5 0.17 12.0 0.7 2.1 3 0 0 3 3 3 0 bZIP transcription factor RT_RNaseH_2 PF17919.1 GBG61956.1 - 2e-27 95.1 0.0 1.1e-26 92.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61956.1 - 2.6e-25 88.7 0.0 8.7e-25 87.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61956.1 - 2.5e-21 76.2 0.0 4.1e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG61956.1 - 5.4e-07 30.2 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG61956.1 - 1.6e-05 24.7 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG61956.1 - 1.9e-05 25.1 0.0 3.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61956.1 - 0.00048 19.9 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG61957.1 - 3e-29 102.1 0.0 4.6e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61957.1 - 2.2e-24 85.4 0.0 4.6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61957.1 - 1.7e-23 82.9 0.0 3.2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61957.1 - 4.2e-16 58.8 0.2 1.1e-15 57.5 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61957.1 - 4.1e-08 33.4 0.1 1.2e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG61957.1 - 0.00017 21.4 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG61957.1 - 0.12 12.6 0.1 0.86 9.9 0.1 2.6 2 1 0 2 2 2 0 H2C2 zinc finger HD_4 PF13328.6 GBG61958.1 - 4.3e-35 120.8 0.4 1.5e-34 119.0 0.1 2.0 2 0 0 2 2 2 1 HD domain RVT_1 PF00078.27 GBG61958.1 - 1.5e-06 27.9 0.2 0.089 12.3 0.0 3.3 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) HD PF01966.22 GBG61958.1 - 1e-05 25.7 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 HD domain RT_RNaseH_2 PF17919.1 GBG61959.1 - 2.6e-31 107.6 0.1 6.4e-31 106.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61959.1 - 1.5e-27 95.9 0.2 3.7e-27 94.7 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61959.1 - 2.5e-26 92.6 0.1 4.7e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG61959.1 - 0.016 15.4 0.0 0.065 13.5 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein NIR_SIR PF01077.22 GBG61959.1 - 0.11 12.0 0.2 0.24 10.9 0.2 1.6 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain RTA1 PF04479.13 GBG61960.1 - 1.5e-05 24.7 15.1 11 5.5 0.0 8.3 2 1 7 9 9 9 1 RTA1 like protein Toprim_N PF08275.11 GBG61960.1 - 2.7e-05 24.2 9.6 15 5.6 0.0 7.9 1 1 7 9 9 9 1 DNA primase catalytic core, N-terminal domain PapC_C PF13953.6 GBG61960.1 - 0.00013 21.8 28.7 1.8 8.4 1.4 7.8 1 1 8 9 9 9 7 PapC C-terminal domain SH3_19 PF18597.1 GBG61960.1 - 0.00031 20.5 37.8 15 5.5 0.2 9.8 10 0 0 10 10 10 6 Myosin X N-terminal SH3 domain Pirin_C PF05726.13 GBG61960.1 - 0.019 15.3 1.7 5.7 7.3 0.1 3.4 1 1 2 3 3 3 0 Pirin C-terminal cupin domain DdrB PF12747.7 GBG61960.1 - 0.49 10.2 16.4 17 5.2 0.3 5.2 1 1 4 6 6 6 0 DdrB-like protein ATP_transf PF09830.9 GBG61960.1 - 0.69 10.1 16.2 46 4.3 0.0 7.3 1 1 8 9 9 9 0 ATP adenylyltransferase Ala_racemase_C PF00842.21 GBG61960.1 - 6.3 6.6 10.4 27 4.6 0.1 4.3 1 1 6 7 7 7 0 Alanine racemase, C-terminal domain rve PF00665.26 GBG61961.1 - 1.1e-14 54.6 0.0 2.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG61961.1 - 7.4e-12 45.2 0.0 2.1e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG61961.1 - 3e-06 27.4 0.4 0.093 13.0 0.1 3.1 3 0 0 3 3 3 2 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG61961.1 - 0.0063 17.0 0.0 0.026 15.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG61961.1 - 0.055 13.3 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG61962.1 - 9.2e-31 105.8 0.0 2.3e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61962.1 - 6.7e-26 90.6 0.1 1.5e-25 89.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61962.1 - 1e-12 48.1 0.3 1.9e-12 47.2 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SIMPL PF04402.14 GBG61962.1 - 0.013 16.0 4.4 1.1 9.7 3.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF541) DUF1564 PF07600.11 GBG61962.1 - 0.014 15.1 0.4 0.037 13.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG61962.1 - 0.03 14.6 0.0 0.03 14.6 0.0 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG61963.1 - 0.0039 17.1 0.5 0.0087 16.0 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG61963.1 - 0.0042 17.3 0.5 0.014 15.7 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein NIR_SIR PF01077.22 GBG61963.1 - 0.15 11.5 0.2 0.29 10.6 0.2 1.4 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain rve PF00665.26 GBG61964.1 - 5.3e-33 113.7 0.0 5.9e-16 58.7 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG61964.1 - 1.9e-31 107.9 1.6 1.9e-14 53.5 0.1 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG61964.1 - 8.7e-14 51.6 0.0 7e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG61964.1 - 0.0026 17.9 3.0 0.011 15.9 0.2 2.6 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 GBG61964.1 - 0.025 14.3 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 Integrase core domain DUF4187 PF13821.6 GBG61965.1 - 0.0057 16.4 1.3 0.0057 16.4 1.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG61965.1 - 0.045 14.0 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein DUF3043 PF11241.8 GBG61965.1 - 2.2 8.3 5.4 3.8 7.5 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) RT_RNaseH_2 PF17919.1 GBG61966.1 - 1.5e-33 114.8 0.1 2.8e-33 113.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61966.1 - 1.1e-30 106.0 0.2 2.2e-30 105.1 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61966.1 - 2.3e-26 92.7 0.1 3.9e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RelA_SpoT PF04607.17 GBG61966.1 - 1.7e-24 86.3 0.0 4.6e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 GBG61966.1 - 0.00032 20.7 0.0 0.00079 19.4 0.0 1.7 1 0 0 1 1 1 1 TGS domain ThiS PF02597.20 GBG61966.1 - 0.034 14.8 0.0 0.54 10.9 0.0 2.5 2 0 0 2 2 2 0 ThiS family ThiS-like PF14453.6 GBG61966.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 ThiS-like ubiquitin Integrase_H2C2 PF17921.1 GBG61967.1 - 3.2e-14 52.8 0.0 9.2e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG61967.1 - 1.5e-13 50.9 0.0 3.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG61967.1 - 0.0034 17.1 0.0 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG61967.1 - 0.015 15.5 0.1 0.033 14.4 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger NPV_P10 PF05531.12 GBG61968.1 - 0.022 15.2 0.9 8.3 7.0 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CHDCT2 PF08074.11 GBG61968.1 - 0.028 14.6 2.1 0.041 14.1 2.1 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain FlaC_arch PF05377.11 GBG61968.1 - 0.066 13.6 2.7 8.1 6.9 0.4 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Mrpl_C PF18502.1 GBG61968.1 - 0.085 13.2 1.3 0.17 12.2 1.1 1.6 1 1 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain DASH_Dam1 PF08653.10 GBG61968.1 - 0.11 12.3 0.2 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 HHH_4 PF14490.6 GBG61968.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain TMF_TATA_bd PF12325.8 GBG61968.1 - 0.12 12.5 4.1 0.56 10.4 2.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 GBG61968.1 - 0.13 12.2 3.4 0.57 10.2 1.8 2.1 1 1 1 2 2 2 0 Laminin Domain II DMPK_coil PF08826.10 GBG61968.1 - 0.27 11.4 3.4 0.47 10.6 1.1 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like Malate_synthase PF01274.22 GBG61969.1 - 2e-216 719.3 0.0 2.3e-216 719.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 GBG61969.1 - 0.01 15.0 0.0 0.036 13.2 0.0 2.0 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family RVT_1 PF00078.27 GBG61970.1 - 3.5e-12 46.3 0.0 6.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG61970.1 - 0.003 17.3 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG61970.1 - 0.039 14.2 0.7 0.039 14.2 0.7 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein DsrH PF04077.12 GBG61971.1 - 0.00057 20.0 0.2 28 4.9 0.0 4.9 1 1 3 5 5 5 1 DsrH like protein SeleniumBinding PF11524.8 GBG61971.1 - 0.16 12.4 8.9 26 5.3 0.2 4.8 1 1 4 5 5 5 0 Selenium binding protein FlgH PF02107.16 GBG61971.1 - 1.3 8.6 5.4 35 4.0 0.1 3.1 2 1 0 3 3 3 0 Flagellar L-ring protein DUF3318 PF11780.8 GBG61971.1 - 4.3 7.3 5.8 25 4.8 0.5 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3318) Aminotran_4 PF01063.19 GBG61972.1 - 2e-34 119.4 0.0 2.5e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV RT_RNaseH_2 PF17919.1 GBG61973.1 - 1.3e-23 82.9 0.0 2.8e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG61973.1 - 9.8e-23 80.8 0.0 1.6e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG61973.1 - 2.8e-19 69.4 0.0 6e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG61973.1 - 0.00037 20.7 0.0 0.0016 18.6 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein SDA1 PF05285.12 GBG61974.1 - 1.1e-06 28.4 17.2 1.6e-06 27.8 17.2 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG61974.1 - 0.0052 15.2 14.5 0.0075 14.6 14.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 GBG61974.1 - 0.13 11.0 2.7 0.18 10.5 2.7 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG61974.1 - 0.19 9.9 34.0 0.31 9.2 34.0 1.2 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 GBG61974.1 - 0.26 10.4 1.3 0.35 10.0 1.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RVT_1 PF00078.27 GBG61975.1 - 5.7e-27 94.7 0.0 8.7e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG61975.1 - 0.012 15.9 0.0 0.042 14.1 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein GreA_GreB_N PF03449.15 GBG61975.1 - 1.7 8.9 7.4 4.8 7.4 4.3 2.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DUF3391 PF11871.8 GBG61975.1 - 7.8 7.0 9.4 1.9 9.1 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Neur_chan_memb PF02932.16 GBG61976.1 - 0.86 9.6 5.8 0.99 9.4 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FTO_NTD PF12933.7 GBG61976.1 - 0.99 8.6 4.8 1.1 8.4 4.8 1.1 1 0 0 1 1 1 0 FTO catalytic domain Fe-ADH_2 PF13685.6 GBG61976.1 - 1 9.0 3.7 1.2 8.8 3.7 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase FapA PF03961.13 GBG61976.1 - 2.4 6.6 13.1 2.6 6.5 13.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A RNA_pol_3_Rpc31 PF11705.8 GBG61976.1 - 3.4 7.9 16.7 4.5 7.4 16.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GAGA_bind PF06217.12 GBG61976.1 - 4.8 7.4 9.4 4.9 7.3 9.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.11 GBG61976.1 - 4.9 7.2 19.5 6 6.9 19.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Vfa1 PF08432.10 GBG61976.1 - 6.8 7.0 15.3 8.4 6.7 15.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RT_RNaseH PF17917.1 GBG61977.1 - 5.1e-24 84.6 0.2 1.4e-23 83.2 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61977.1 - 7.2e-15 54.9 0.0 1.7e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61977.1 - 2.7e-12 46.6 0.3 5.9e-12 45.5 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain FtsK_4TM PF13491.6 GBG61977.1 - 0.047 13.4 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE Apc13p PF05839.11 GBG61977.1 - 0.08 13.1 0.5 0.23 11.7 0.5 1.8 1 0 0 1 1 1 0 Apc13p protein DUF1140 PF06600.11 GBG61977.1 - 4.3 7.9 4.4 24 5.5 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1140) FAM199X PF15814.5 GBG61977.1 - 9.1 5.2 6.8 14 4.6 6.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X RVT_1 PF00078.27 GBG61978.1 - 4.6e-52 176.7 0.4 4.6e-26 91.7 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG61978.1 - 8.8e-46 154.0 0.0 1.3e-25 89.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61978.1 - 3.8e-36 123.5 0.0 1.1e-22 80.3 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG61978.1 - 1.4e-06 28.8 0.0 2.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG61978.1 - 1.8e-05 25.2 0.0 4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG61978.1 - 0.00028 20.7 0.0 0.0016 18.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG61978.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease APG17 PF04108.12 GBG61978.1 - 0.027 13.6 0.0 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Autophagy protein Apg17 DUF4399 PF14347.6 GBG61978.1 - 0.14 12.5 0.2 31 5.0 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) RT_RNaseH_2 PF17919.1 GBG61981.1 - 1.6e-33 114.7 0.2 4.7e-33 113.2 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG61981.1 - 3.8e-31 107.5 0.0 1.1e-30 106.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG61981.1 - 3.1e-15 56.4 0.5 2.3e-14 53.6 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG61981.1 - 3e-07 30.5 0.1 6.7e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG61981.1 - 3e-06 26.9 0.0 5.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG61981.1 - 4.7e-05 23.5 0.1 0.00011 22.3 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger SATase_N PF06426.14 GBG61983.1 - 1.6e-36 124.8 0.2 3.1e-36 123.9 0.2 1.5 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 GBG61983.1 - 3.9e-08 32.7 6.0 1.3e-05 24.7 0.5 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GBG61983.1 - 0.084 12.6 4.6 0.081 12.7 1.4 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Methyltransf_31 PF13847.6 GBG61984.1 - 1.1e-21 77.3 0.0 1.7e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG61984.1 - 1.8e-14 54.2 0.1 3.8e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG61984.1 - 6.9e-13 49.1 0.1 1.5e-12 48.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG61984.1 - 5.3e-11 43.1 0.1 1.1e-10 42.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG61984.1 - 1.1e-09 38.3 0.0 2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG61984.1 - 1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 GBG61984.1 - 6.1e-06 25.8 0.0 9.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 GBG61984.1 - 0.00087 18.8 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 GBG61984.1 - 0.00091 18.9 0.0 0.0019 17.9 0.0 1.5 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 GBG61984.1 - 0.002 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 GBG61984.1 - 0.0049 16.2 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 GBG61984.1 - 0.005 16.4 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 GBG61984.1 - 0.037 13.5 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Pox_MCEL PF03291.16 GBG61984.1 - 0.14 11.2 0.0 0.44 9.6 0.0 1.6 2 0 0 2 2 2 0 mRNA capping enzyme AdoMet_MTase PF07757.13 GBG61984.1 - 0.2 12.0 0.0 0.42 11.0 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Ribosomal_60s PF00428.19 GBG61984.1 - 1.2 9.8 11.3 2.1 9.0 4.8 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Surp PF01805.20 GBG61985.1 - 6.4e-17 61.3 0.0 1.7e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 GBG61985.1 - 1.7e-13 50.2 0.0 3.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 GBG61985.1 - 0.00017 22.3 0.0 0.00048 20.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 GBG61985.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif CTK3 PF12243.8 GBG61985.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF659 PF04937.15 GBG61987.1 - 6.7e-29 100.7 0.3 1.2e-28 99.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG61987.1 - 0.00013 21.7 0.1 0.00035 20.3 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG61987.1 - 0.00032 21.2 0.0 0.00086 19.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61987.1 - 0.03 14.9 0.0 0.091 13.4 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Lipase_3 PF01764.25 GBG61988.1 - 5.6e-15 55.4 0.0 9.3e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase_3 PF01764.25 GBG61989.1 - 5.5e-15 55.5 0.0 9.1e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) LAT PF15234.6 GBG61989.1 - 1.5 8.5 4.8 3.1 7.5 4.8 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells DUF3138 PF11336.8 GBG61990.1 - 0.61 8.6 3.7 0.4 9.2 2.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) gag-asp_proteas PF13975.6 GBG61992.1 - 6.1e-07 29.9 0.1 1.6e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG61992.1 - 4.8e-05 23.9 0.1 0.00012 22.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG61992.1 - 0.00029 20.6 0.1 0.00051 19.8 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG61992.1 - 0.02 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Fasciclin PF02469.22 GBG61993.1 - 2.1e-19 70.0 0.0 2.7e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain DUF659 PF04937.15 GBG61995.1 - 1.2e-29 103.1 0.0 2.2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG61995.1 - 3.5e-23 81.9 0.0 1e-22 80.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG61995.1 - 7.2e-23 80.5 0.0 2.2e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG61995.1 - 1.5e-15 57.0 0.1 4.8e-15 55.4 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG61995.1 - 0.0062 16.8 0.0 0.027 14.7 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein WTX PF09422.10 GBG61995.1 - 0.025 13.7 3.0 0.039 13.0 3.0 1.2 1 0 0 1 1 1 0 WTX protein TolA_bind_tri PF16331.5 GBG61995.1 - 0.063 13.4 5.1 0.18 11.9 5.1 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3492 PF11997.8 GBG61995.1 - 0.36 10.5 2.8 0.85 9.3 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) muHD PF10291.9 GBG61996.1 - 3.8e-15 56.1 0.0 6.6e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.21 GBG61996.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Integrase_H2C2 PF17921.1 GBG61996.1 - 0.0033 17.5 0.5 0.0054 16.8 0.5 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain PI3K_P85_iSH2 PF16454.5 GBG61998.1 - 0.0037 16.9 11.1 0.0037 16.9 11.1 9.2 5 3 4 9 9 9 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BTB PF00651.31 GBG61999.1 - 7.8e-15 55.1 0.0 2.1e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 GBG61999.1 - 0.00065 19.8 0.0 0.014 15.6 0.0 2.4 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain EF-hand_1 PF00036.32 GBG62000.1 - 2.6e-30 101.7 0.2 2.1e-07 30.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GBG62000.1 - 6.8e-29 100.1 0.7 1.8e-13 50.7 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG62000.1 - 2.1e-27 92.7 1.1 7.8e-08 31.7 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GBG62000.1 - 2.8e-21 74.0 4.9 2.4e-05 23.6 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 GBG62000.1 - 9.1e-20 70.3 1.0 1.4e-09 37.6 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 GBG62000.1 - 1e-08 35.3 0.0 1.2e-05 25.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GBG62000.1 - 2.8e-06 27.2 0.7 0.00061 19.7 0.0 2.6 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 GBG62000.1 - 4.9e-06 27.4 0.0 0.13 13.1 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GBG62000.1 - 2.8e-05 24.4 0.0 0.015 15.6 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GBG62000.1 - 0.00092 19.4 0.1 0.025 14.8 0.1 2.7 2 1 1 3 3 3 1 Dockerin type I domain UPF0154 PF03672.13 GBG62000.1 - 0.0022 18.0 0.0 0.15 12.1 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_10 PF14788.6 GBG62000.1 - 0.004 17.0 1.9 0.61 10.0 0.1 3.2 3 0 0 3 3 3 1 EF hand FANCI_S1-cap PF14674.6 GBG62000.1 - 0.0067 16.5 4.8 4.9 7.3 0.1 3.6 3 0 0 3 3 3 1 FANCI solenoid 1 cap DUF1456 PF07308.13 GBG62000.1 - 0.0091 16.3 0.7 0.23 11.8 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1456) SurA_N_3 PF13624.6 GBG62000.1 - 0.045 13.5 0.2 0.11 12.3 0.1 1.6 1 1 1 2 2 2 0 SurA N-terminal domain DUF5109 PF17134.4 GBG62000.1 - 0.059 13.3 0.3 14 5.6 0.1 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF5109) VCBS PF13517.6 GBG62000.1 - 0.061 13.9 0.2 0.11 13.1 0.2 1.6 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Caleosin PF05042.13 GBG62000.1 - 0.11 12.4 0.1 9.8 6.1 0.0 2.4 1 1 0 2 2 2 0 Caleosin related protein Nop14 PF04147.12 GBG62001.1 - 1.5 7.0 25.5 1.8 6.7 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG62001.1 - 2.1 7.7 25.7 2.7 7.4 25.7 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 GBG62001.1 - 3.1 7.4 13.2 4 7.1 13.2 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) EF-hand_1 PF00036.32 GBG62002.1 - 9.2e-30 100.0 0.3 2.4e-07 29.8 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GBG62002.1 - 3.3e-29 101.2 1.8 1.3e-13 51.2 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG62002.1 - 1.5e-26 90.0 1.4 1.3e-07 31.0 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GBG62002.1 - 2.6e-21 74.1 1.9 1.1e-05 24.7 0.0 4.5 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.6 GBG62002.1 - 1.1e-19 70.0 1.2 5e-09 35.9 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 GBG62002.1 - 1.7e-09 37.8 0.1 7e-06 26.3 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 GBG62002.1 - 8.2e-07 29.9 0.0 0.044 14.7 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GBG62002.1 - 1.6e-06 28.0 1.3 0.00021 21.2 0.1 2.6 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GBG62002.1 - 6.7e-06 26.4 0.0 0.0055 17.0 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GBG62002.1 - 0.00068 19.8 0.2 0.073 13.3 0.1 3.1 2 1 1 3 3 3 1 Dockerin type I domain UPF0154 PF03672.13 GBG62002.1 - 0.0012 18.9 0.0 0.15 12.1 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) DUF1456 PF07308.13 GBG62002.1 - 0.0094 16.3 0.9 0.23 11.8 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1456) EF-hand_10 PF14788.6 GBG62002.1 - 0.015 15.2 2.8 2 8.4 0.1 3.2 3 0 0 3 3 3 0 EF hand SurA_N_3 PF13624.6 GBG62002.1 - 0.028 14.2 0.6 0.055 13.3 0.3 1.6 1 1 1 2 2 2 0 SurA N-terminal domain Caleosin PF05042.13 GBG62002.1 - 0.029 14.3 0.1 2.7 7.9 0.0 2.5 2 2 0 2 2 2 0 Caleosin related protein Beta-lactamase2 PF13354.6 GBG62002.1 - 0.03 13.9 0.0 0.12 12.0 0.0 1.9 1 1 1 2 2 2 0 Beta-lactamase enzyme family PMBR PF09373.10 GBG62002.1 - 0.063 13.5 0.0 56 4.1 0.0 3.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat EF-hand_14 PF17959.1 GBG62002.1 - 0.097 13.0 0.1 18 5.8 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain PHB_acc_N PF07879.11 GBG62002.1 - 0.098 12.8 0.0 5.5 7.1 0.0 2.5 2 1 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain Fe_hyd_lg_C PF02906.14 GBG62002.1 - 0.11 12.1 0.3 9.5 5.8 0.1 2.0 1 1 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain DUF1840 PF08895.11 GBG62002.1 - 0.12 12.7 0.7 7.4 7.0 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1840) FANCI_S1-cap PF14674.6 GBG62002.1 - 0.15 12.2 5.7 13 6.0 0.2 3.5 3 0 0 3 3 3 0 FANCI solenoid 1 cap DUF1007 PF06226.13 GBG62002.1 - 0.18 11.8 0.7 0.71 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1007) Toprim PF01751.22 GBG62002.1 - 0.18 12.0 0.8 3.1 8.1 0.0 2.5 1 1 1 2 2 2 0 Toprim domain SET PF00856.28 GBG62003.1 - 1.4e-11 45.1 0.1 5.3e-11 43.2 0.1 2.1 1 0 0 1 1 1 1 SET domain SET PF00856.28 GBG62004.1 - 1.3e-11 45.2 0.1 5.1e-11 43.2 0.1 2.1 1 0 0 1 1 1 1 SET domain Ribosomal_S21e PF01249.18 GBG62006.1 - 3.1e-38 129.7 0.0 3.6e-38 129.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Drc1-Sld2 PF11719.8 GBG62007.1 - 1.1 8.7 28.7 1.1 8.7 28.7 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein SDA1 PF05285.12 GBG62007.1 - 4.7 6.5 43.5 5.7 6.3 43.5 1.1 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG62008.1 - 0.016 15.5 23.6 0.023 15.0 23.6 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated HAP1_N PF04849.13 GBG62009.1 - 0.011 15.0 0.1 5.2 6.2 0.0 3.3 2 1 1 3 3 3 0 HAP1 N-terminal conserved region RT_RNaseH PF17917.1 GBG62010.1 - 5.8e-28 97.3 0.0 1.3e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62010.1 - 6.4e-28 97.8 0.0 1.4e-27 96.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62010.1 - 5.3e-27 93.8 0.0 8.1e-13 48.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62010.1 - 4.8e-16 58.6 0.0 1.1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62010.1 - 1.1e-09 38.4 0.3 4.1e-09 36.7 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG62010.1 - 1.8e-05 24.9 0.0 5.9e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG62011.1 - 0.0042 17.6 0.6 0.029 14.9 0.0 2.5 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62011.1 - 0.015 15.9 0.1 0.089 13.4 0.0 2.3 2 1 1 3 3 3 0 Aspartyl protease RVP PF00077.20 GBG62011.1 - 0.087 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Spore_coat_CotO PF14153.6 GBG62013.1 - 0.31 10.9 13.8 0.38 10.6 13.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Retrotrans_gag PF03732.17 GBG62015.1 - 0.014 15.6 0.3 0.11 12.8 0.1 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein DUF1664 PF07889.12 GBG62015.1 - 0.04 13.9 0.3 3.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RVT_1 PF00078.27 GBG62017.1 - 4.9e-33 114.5 0.1 8.4e-33 113.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62017.1 - 4e-32 110.2 0.0 7.8e-32 109.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62017.1 - 1.4e-28 99.3 0.1 3e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mcp5_PH PF12814.7 GBG62017.1 - 0.12 12.4 0.4 0.76 9.9 0.4 2.1 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology DUF5095 PF17016.5 GBG62017.1 - 0.16 11.6 0.2 0.29 10.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Retrotrans_gag PF03732.17 GBG62018.1 - 0.012 15.8 1.7 0.26 11.6 0.1 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG62019.1 - 1.3e-36 126.2 0.1 2.2e-36 125.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62019.1 - 1.8e-24 85.7 0.0 4.1e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62019.1 - 4.4e-22 78.3 0.0 9e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Toxin_4 PF00706.17 GBG62021.1 - 0.084 13.3 0.6 0.16 12.4 0.6 1.4 1 0 0 1 1 1 0 Anenome neurotoxin SDA1 PF05285.12 GBG62021.1 - 3.9 6.8 18.4 4.9 6.5 18.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG62021.1 - 5.5 5.2 13.6 7.2 4.8 13.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SUIM_assoc PF16619.5 GBG62022.1 - 0.46 10.6 38.6 0.12 12.4 8.7 6.5 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 DUF1421 PF07223.11 GBG62022.1 - 1.9 8.4 3.6 0.87 9.5 0.1 2.1 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Laminin_G_3 PF13385.6 GBG62023.1 - 2e-07 31.3 0.1 7.2e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Presenilin PF01080.17 GBG62023.1 - 0.27 10.0 11.7 0.32 9.7 11.7 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 GBG62023.1 - 0.29 11.1 31.6 0.36 10.8 31.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF413 PF04219.12 GBG62023.1 - 0.51 10.4 5.5 0.92 9.6 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF PAP2 PF01569.21 GBG62023.1 - 2.1 8.1 6.4 1.4 8.7 2.1 2.3 2 1 0 2 2 2 0 PAP2 superfamily Lin-8 PF03353.15 GBG62023.1 - 2.3 7.7 16.4 4.3 6.8 16.4 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 GBG62023.1 - 8.9 4.4 24.1 10 4.2 24.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Na_trans_assoc PF06512.13 GBG62025.1 - 0.00076 19.8 7.5 0.00089 19.6 7.5 1.4 1 0 0 1 1 1 1 Sodium ion transport-associated DUF2201_N PF13203.6 GBG62025.1 - 0.53 9.8 5.6 0.74 9.4 5.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain SDA1 PF05285.12 GBG62025.1 - 2.3 7.5 33.9 3 7.2 33.9 1.1 1 0 0 1 1 1 0 SDA1 VIR_N PF15912.5 GBG62025.1 - 5 6.6 20.1 7.1 6.1 20.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal zf-CCHC PF00098.23 GBG62026.1 - 4.2e-05 23.4 1.6 4.2e-05 23.4 1.6 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG62026.1 - 0.015 15.1 0.5 0.015 15.1 0.5 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG62026.1 - 0.064 13.1 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle CLN3 PF02487.17 GBG62026.1 - 0.085 11.9 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 CLN3 protein RPN2_C PF18004.1 GBG62026.1 - 0.2 11.6 12.8 0.27 11.2 12.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1943 PF09172.11 GBG62026.1 - 1.7 7.8 4.8 2.2 7.4 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF4337 PF14235.6 GBG62026.1 - 5.3 7.1 7.9 7.4 6.7 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Connexin PF00029.19 GBG62026.1 - 6.7 6.4 5.0 8.8 6.0 5.0 1.1 1 0 0 1 1 1 0 Connexin gag-asp_proteas PF13975.6 GBG62027.1 - 1.3e-08 35.2 0.0 2.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62027.1 - 2.6e-06 28.0 0.0 6.4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62027.1 - 0.00014 21.6 0.2 0.00026 20.7 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG62027.1 - 0.00085 19.6 0.0 0.0026 18.0 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG62027.1 - 0.0037 16.8 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG62029.1 - 1.5e-29 103.1 0.1 2.9e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62029.1 - 2.8e-17 62.9 0.1 6.9e-17 61.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62029.1 - 1.8e-15 56.8 0.1 4e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62029.1 - 7.1e-15 55.2 0.0 2.2e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG62029.1 - 8.1e-10 38.6 0.0 2.8e-09 36.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BAF250_C PF12031.8 GBG62029.1 - 0.075 12.3 0.1 0.2 10.9 0.1 1.7 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa DUF1564 PF07600.11 GBG62029.1 - 0.31 10.7 2.0 0.43 10.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) RT_RNaseH_2 PF17919.1 GBG62030.1 - 1e-31 108.9 0.3 2.4e-31 107.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62030.1 - 2.6e-29 101.6 0.1 6.6e-29 100.3 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62030.1 - 6.5e-24 84.7 1.0 4.3e-11 42.7 0.1 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG62031.1 - 2.9e-08 33.5 0.1 4.9e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG62031.1 - 0.00011 22.1 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG62031.1 - 0.00033 20.9 1.0 0.00069 19.8 0.2 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG62031.1 - 0.0078 16.0 0.8 0.019 14.8 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RVP_2 PF08284.11 GBG62031.1 - 0.016 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62031.1 - 0.15 12.8 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Lectin_C PF00059.21 GBG62032.1 - 1e-09 39.1 0.9 0.00055 20.6 0.0 3.5 3 0 0 3 3 3 2 Lectin C-type domain Xlink PF00193.17 GBG62032.1 - 0.02 15.3 5.2 2.1 8.8 0.0 4.0 3 1 1 4 4 4 0 Extracellular link domain Snapin_Pallidin PF14712.6 GBG62032.1 - 0.046 14.2 0.0 0.046 14.2 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Jnk-SapK_ap_N PF09744.9 GBG62032.1 - 8.6 6.6 9.8 19 5.5 9.8 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 RVT_1 PF00078.27 GBG62033.1 - 7.3e-30 104.1 0.0 1.4e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62033.1 - 4.9e-19 68.2 0.0 5.4e-16 58.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62033.1 - 3.1e-07 30.6 0.0 7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Histone PF00125.24 GBG62034.1 - 9e-21 74.6 0.1 9e-21 74.6 0.1 2.4 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 BCAS2 PF05700.11 GBG62034.1 - 0.0052 16.5 5.7 0.011 15.4 5.7 1.5 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Exonuc_VII_L PF02601.15 GBG62034.1 - 0.029 13.9 1.6 0.052 13.1 1.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 GBG62034.1 - 0.068 12.0 10.9 0.06 12.2 6.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein HMMR_N PF15905.5 GBG62034.1 - 0.11 12.0 7.8 0.25 10.7 7.8 1.6 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 GBG62034.1 - 0.12 11.8 10.4 0.24 10.9 10.4 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 GBG62034.1 - 0.55 10.3 10.0 0.11 12.5 5.4 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4485 PF14846.6 GBG62034.1 - 0.73 9.9 2.9 3.6 7.7 2.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4485) PspB PF06667.12 GBG62034.1 - 2.7 8.1 5.2 1.3 9.1 0.3 2.3 1 1 1 2 2 2 0 Phage shock protein B DHR10 PF18595.1 GBG62034.1 - 2.8 8.0 17.9 0.025 14.6 4.5 3.0 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain ArsA_ATPase PF02374.15 GBG62035.1 - 2.4e-62 210.9 1.3 2.9e-62 210.6 1.3 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase DUF4515 PF14988.6 GBG62035.1 - 9.1e-05 22.4 4.5 0.00016 21.6 0.6 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4515) WD40_alt PF14077.6 GBG62035.1 - 0.00094 19.0 1.8 0.0041 16.9 0.1 2.6 3 0 0 3 3 3 1 Alternative WD40 repeat motif Cytochrom_C_2 PF01322.20 GBG62035.1 - 0.0047 17.8 0.3 0.13 13.1 0.0 2.3 2 1 0 2 2 2 1 Cytochrome C' Tim44 PF04280.15 GBG62035.1 - 0.022 14.9 0.7 0.037 14.1 0.7 1.3 1 0 0 1 1 1 0 Tim44-like domain FlaC_arch PF05377.11 GBG62035.1 - 0.037 14.4 0.7 1.7 9.1 0.0 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Band_7_1 PF13421.6 GBG62035.1 - 0.093 12.4 0.6 0.13 11.9 0.6 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family DivIVA PF05103.13 GBG62035.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.2 2 1 1 3 3 3 0 DivIVA protein Trimer_CC PF08954.11 GBG62035.1 - 2 8.0 7.8 26 4.5 0.5 3.6 3 1 0 3 3 3 0 Trimerisation motif Rad51 PF08423.11 GBG62036.1 - 1.6e-40 139.0 0.0 2.4e-21 76.2 0.0 2.1 2 0 0 2 2 2 2 Rad51 ATPase PF06745.13 GBG62036.1 - 5.6e-05 22.6 0.0 0.00069 19.0 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 GBG62036.1 - 0.0003 20.4 0.0 0.073 12.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain RecA PF00154.21 GBG62036.1 - 0.0038 16.7 0.1 0.44 10.0 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.15 GBG62036.1 - 0.0045 16.3 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain CAP_N PF01213.19 GBG62036.1 - 3.6 7.0 4.4 5.9 6.3 4.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Hist_deacetyl PF00850.19 GBG62038.1 - 6.2e-83 278.8 0.2 9.7e-83 278.2 0.2 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Nop14 PF04147.12 GBG62038.1 - 0.072 11.3 16.4 0.1 10.8 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 GBG62038.1 - 1.7 8.1 10.5 3 7.4 10.5 1.4 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 GBG62038.1 - 4.9 6.4 12.4 9.5 5.4 12.4 1.5 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 GBG62038.1 - 5.1 6.1 7.6 8.6 5.3 7.6 1.3 1 0 0 1 1 1 0 Pes-10 RVT_1 PF00078.27 GBG62039.1 - 2e-29 102.7 0.0 4.5e-29 101.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62039.1 - 1.6e-24 85.9 0.0 4.9e-24 84.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62039.1 - 3.1e-19 68.8 0.4 8.9e-19 67.4 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG62039.1 - 9.4e-16 58.0 0.0 3.4e-15 56.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62039.1 - 5.5e-09 36.3 0.0 2e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG62039.1 - 5.4e-08 33.4 0.0 2e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62039.1 - 1e-06 29.2 0.0 3.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62039.1 - 6.2e-06 26.0 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62039.1 - 0.00085 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG62039.1 - 0.014 15.6 4.3 2.2 8.6 0.0 4.1 3 0 0 3 3 3 0 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG62039.1 - 0.018 15.6 1.9 0.018 15.6 1.9 4.1 5 0 0 5 5 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-H2C2 PF09337.10 GBG62039.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger CENP-F_leu_zip PF10473.9 GBG62041.1 - 0.69 9.9 16.2 3.5 7.7 16.2 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Copine PF07002.16 GBG62042.1 - 4e-56 189.9 0.0 6.3e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 GBG62042.1 - 1.7e-13 50.8 0.0 2.1e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GBG62042.1 - 0.058 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus zf-CCHC PF00098.23 GBG62043.1 - 1.2e-07 31.4 2.2 1.9e-07 30.8 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG62043.1 - 0.0045 16.9 0.7 0.011 15.7 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 GBG62043.1 - 0.012 16.0 0.3 0.012 16.0 0.3 2.6 3 0 0 3 3 2 0 Eukaryotic translation initiation factor 3 subunit G DUF4355 PF14265.6 GBG62043.1 - 0.013 15.7 16.4 0.024 14.9 16.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) NPAT_C PF15712.5 GBG62043.1 - 0.036 12.7 7.4 0.046 12.4 7.4 1.1 1 0 0 1 1 1 0 NPAT C terminus eIF3_subunit PF08597.10 GBG62043.1 - 0.039 13.9 18.4 0.056 13.3 18.4 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit zf-CCHC_2 PF13696.6 GBG62043.1 - 0.063 13.1 1.2 0.1 12.5 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle RR_TM4-6 PF06459.12 GBG62043.1 - 0.082 12.7 10.4 0.12 12.2 10.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP70 PF00012.20 GBG62043.1 - 0.15 10.2 7.2 0.18 9.9 7.2 1.1 1 0 0 1 1 1 0 Hsp70 protein Vfa1 PF08432.10 GBG62043.1 - 0.16 12.3 13.1 0.29 11.4 13.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hid1 PF12722.7 GBG62043.1 - 0.2 9.8 4.8 0.22 9.6 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Atg14 PF10186.9 GBG62043.1 - 0.3 10.1 6.9 0.35 9.9 6.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2514 PF10721.9 GBG62043.1 - 0.3 11.1 15.4 0.63 10.1 15.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Endonuc_Holl PF10107.9 GBG62043.1 - 0.43 10.4 12.9 0.59 10.0 12.9 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Macoilin PF09726.9 GBG62043.1 - 0.44 9.1 12.6 0.52 8.8 12.6 1.1 1 0 0 1 1 1 0 Macoilin family Radial_spoke_3 PF06098.11 GBG62043.1 - 0.48 9.6 19.1 0.069 12.4 14.6 1.8 2 0 0 2 2 2 0 Radial spoke protein 3 DDRGK PF09756.9 GBG62043.1 - 0.88 9.1 24.6 0.056 13.0 19.2 1.7 2 0 0 2 2 2 0 DDRGK domain AP1AR PF15745.5 GBG62043.1 - 1 8.9 20.1 0.088 12.4 15.4 1.6 2 0 0 2 2 2 0 AP-1 complex-associated regulatory protein DUF1682 PF07946.14 GBG62043.1 - 1.2 8.3 21.0 1.6 7.8 21.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AAA_11 PF13086.6 GBG62043.1 - 1.7 8.3 8.9 2.3 7.9 8.9 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 GBG62043.1 - 2.2 6.1 4.2 2.2 6.1 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc4 PF05132.14 GBG62043.1 - 2.5 8.5 6.2 4.2 7.8 6.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.8 GBG62043.1 - 2.9 6.7 15.1 3.7 6.4 15.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BT1 PF03092.16 GBG62043.1 - 2.9 6.0 4.4 3.7 5.7 4.4 1.1 1 0 0 1 1 1 0 BT1 family Borrelia_P83 PF05262.11 GBG62043.1 - 4.1 5.8 15.9 5.1 5.5 15.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ribosomal_S15 PF00312.22 GBG62044.1 - 6e-30 103.3 0.7 9.2e-30 102.7 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 RRM_1 PF00076.22 GBG62045.1 - 3.6e-15 55.5 0.0 6.1e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 GBG62045.1 - 2.3e-08 34.4 13.3 2.3e-08 34.4 13.3 3.6 3 2 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 DUF4957 PF16318.5 GBG62045.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4957) Adaptin_N PF01602.20 GBG62046.1 - 9.6e-94 314.8 10.1 1.4e-93 314.2 10.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 GBG62046.1 - 7.6e-60 200.9 0.3 1.4e-59 200.0 0.3 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 GBG62046.1 - 1.4e-59 199.7 0.0 4e-59 198.2 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 GBG62046.1 - 7e-07 29.5 1.7 0.0065 16.8 0.0 4.9 2 1 2 5 5 5 1 HEAT repeats HEAT PF02985.22 GBG62046.1 - 1e-06 28.4 0.6 0.008 16.4 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Coatomer_g_Cpla PF16381.5 GBG62046.1 - 0.0014 18.7 0.1 0.0051 16.9 0.0 2.1 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Cnd1 PF12717.7 GBG62046.1 - 0.0017 18.4 9.1 0.0069 16.5 0.5 4.2 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Alpha_adaptinC2 PF02883.20 GBG62046.1 - 0.076 13.3 0.0 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 Adaptin C-terminal domain RVT_1 PF00078.27 GBG62047.1 - 5.3e-35 120.9 0.1 8.8e-35 120.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BSD PF03909.17 GBG62047.1 - 1.3e-17 63.5 0.0 9e-13 48.0 0.1 2.8 2 0 0 2 2 2 2 BSD domain RT_RNaseH_2 PF17919.1 GBG62047.1 - 4.1e-15 55.6 0.0 1.2e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PH_TFIIH PF08567.11 GBG62047.1 - 1.5e-08 34.8 0.3 4.3e-08 33.4 0.3 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain RVP_2 PF08284.11 GBG62047.1 - 5e-07 29.6 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62047.1 - 9.9e-06 26.1 0.0 2.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG62047.1 - 1.2e-05 25.5 0.0 4.5e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG62047.1 - 0.0002 21.9 0.1 0.0014 19.2 0.0 2.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG62047.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG62047.1 - 0.0033 17.2 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF4392 PF14336.6 GBG62047.1 - 0.011 15.2 0.2 0.037 13.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) RVT_1 PF00078.27 GBG62048.1 - 2.4e-29 102.5 0.1 4.5e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62048.1 - 2.9e-28 97.8 0.0 6.5e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62048.1 - 3e-25 88.5 0.0 6.9e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62048.1 - 1.7e-19 70.2 0.0 3.9e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG62048.1 - 3.5e-16 59.1 0.1 9.4e-16 57.7 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG62048.1 - 2.2e-05 24.5 0.0 8.1e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG62048.1 - 0.0041 16.8 2.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 2 Phage capsid scaffolding protein (GPO) serine peptidase tRNA_lig_CPD PF08302.11 GBG62048.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain rve_3 PF13683.6 GBG62048.1 - 0.15 11.8 0.0 0.63 9.9 0.0 2.2 1 0 0 1 1 1 0 Integrase core domain FUSC PF04632.12 GBG62048.1 - 0.3 9.6 4.7 0.33 9.4 0.0 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family Med3 PF11593.8 GBG62048.1 - 0.47 9.6 3.0 0.76 8.9 3.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YabA PF06156.13 GBG62048.1 - 0.63 10.7 4.2 0.83 10.3 0.0 3.1 4 0 0 4 4 3 0 Initiation control protein YabA GCN5L1 PF06320.13 GBG62048.1 - 9.7 6.4 9.5 1.5 9.0 4.4 2.3 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Mrr_N PF14338.6 GBG62049.1 - 0.044 13.9 0.0 0.45 10.7 0.0 2.0 1 1 1 2 2 2 0 Mrr N-terminal domain FRD2 PF03197.13 GBG62049.1 - 0.054 13.8 0.4 0.095 13.0 0.4 1.4 1 0 0 1 1 1 0 Bacteriophage FRD2 protein DDE_Tnp_4 PF13359.6 GBG62050.1 - 1.4e-21 76.9 0.0 2.1e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62050.1 - 2.9e-14 53.2 0.0 5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG62050.1 - 0.1 12.2 0.1 14 5.3 0.0 2.7 1 1 1 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG62051.1 - 2.3e-08 34.3 4.8 2.3e-08 34.3 4.8 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG62051.1 - 0.11 12.7 1.2 0.27 11.5 1.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain rve PF00665.26 GBG62052.1 - 1.5e-14 54.2 0.0 3.5e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain NIF PF03031.18 GBG62052.1 - 0.0041 16.9 0.1 0.0087 15.8 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Tmemb_cc2 PF10267.9 GBG62052.1 - 0.036 13.2 6.8 0.13 11.4 6.8 1.9 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.9 GBG62052.1 - 0.42 9.1 13.1 1.1 7.7 13.1 1.7 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 GBG62052.1 - 1.1 7.7 9.4 2.1 6.7 9.4 1.4 1 0 0 1 1 1 0 Peptidase family S64 FAM76 PF16046.5 GBG62052.1 - 2.4 7.4 5.6 5.6 6.2 5.6 1.5 1 0 0 1 1 1 0 FAM76 protein NIF PF03031.18 GBG62053.1 - 4.9e-52 175.8 0.1 7.7e-52 175.2 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RVT_1 PF00078.27 GBG62054.1 - 1.7e-08 34.2 0.0 2.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG62054.1 - 1.5e-05 25.4 0.2 4.3e-05 24.0 0.2 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62054.1 - 0.0013 19.3 0.2 0.0036 17.9 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62054.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG62054.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG62054.1 - 8.7 6.6 6.4 1.3 9.2 1.9 2.1 2 0 0 2 2 2 0 Zinc knuckle ChaC PF04752.12 GBG62055.1 - 2.8e-15 56.8 0.0 4.7e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein RT_RNaseH PF17917.1 GBG62056.1 - 9.8e-31 106.2 0.0 2.7e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62056.1 - 1.4e-24 86.0 0.0 3.7e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG62056.1 - 0.0014 18.8 0.2 0.022 15.0 0.0 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein gpUL132 PF11359.8 GBG62056.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Cmc1 PF08583.10 GBG62057.1 - 0.32 11.0 4.2 2 8.5 0.3 2.3 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 GBG62057.1 - 0.37 11.1 6.4 0.37 11.1 2.6 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 ABC_tran PF00005.27 GBG62058.1 - 3.4e-14 53.5 0.0 1.2e-13 51.7 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG62058.1 - 7.1e-11 42.5 0.7 1.1e-05 25.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GBG62058.1 - 0.00093 18.8 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GBG62058.1 - 0.0091 15.7 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 GBG62058.1 - 0.095 12.9 0.1 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GBG62058.1 - 0.098 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 GBG62058.1 - 0.11 13.0 0.2 0.22 12.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 GBG62058.1 - 0.15 11.5 0.2 0.45 9.9 0.1 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_24 PF13479.6 GBG62058.1 - 0.21 11.3 0.0 0.52 10.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 GBG62058.1 - 0.21 9.0 2.2 0.11 10.0 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF659 PF04937.15 GBG62059.1 - 2.9e-31 108.4 0.2 8.6e-31 106.8 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) EF-hand_1 PF00036.32 GBG62061.1 - 2.9e-35 117.2 15.5 3.1e-09 35.7 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GBG62061.1 - 1.9e-31 108.3 6.9 5e-16 58.9 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG62061.1 - 3.8e-27 91.8 8.9 1.8e-08 33.7 0.1 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GBG62061.1 - 3.6e-26 89.5 10.8 1.3e-07 30.7 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GBG62061.1 - 7.1e-23 80.2 14.4 1.1e-10 41.2 1.2 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 GBG62061.1 - 1.3e-14 54.2 0.4 7.5e-07 29.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GBG62061.1 - 2.5e-09 37.4 0.8 0.001 19.3 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GBG62061.1 - 9.7e-08 31.9 7.8 0.00011 22.1 0.4 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 GBG62061.1 - 2.3e-06 27.7 2.2 0.00045 20.4 0.3 3.0 2 2 1 3 3 3 1 Dockerin type I domain EF-hand_11 PF08976.11 GBG62061.1 - 4.5e-05 24.3 0.1 0.027 15.3 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 GBG62061.1 - 8.3e-05 22.6 0.0 0.18 11.7 0.0 2.8 2 2 1 3 3 3 2 Caleosin related protein TerB PF05099.13 GBG62061.1 - 0.0004 20.4 3.0 0.061 13.3 0.7 2.3 2 0 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_14 PF17959.1 GBG62061.1 - 0.00054 20.3 1.1 0.91 9.9 0.1 2.4 1 1 0 2 2 2 2 EF-hand domain SurA_N_3 PF13624.6 GBG62061.1 - 0.0021 17.8 1.3 0.038 13.8 0.2 2.1 1 1 1 2 2 2 1 SurA N-terminal domain Sen15 PF09631.10 GBG62061.1 - 0.0071 16.6 0.2 3.5 8.0 0.1 2.1 2 0 0 2 2 2 1 Sen15 protein UBA_6 PF18039.1 GBG62061.1 - 0.011 15.6 0.8 2 8.4 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain SurA_N_2 PF13623.6 GBG62061.1 - 0.014 15.3 4.2 0.14 12.0 0.2 2.6 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 GBG62061.1 - 0.014 14.0 0.1 0.086 11.4 0.1 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5580) Rota_NSP3 PF01665.16 GBG62061.1 - 0.029 13.5 1.6 0.05 12.7 0.1 1.8 2 0 0 2 2 2 0 Rotavirus non-structural protein NSP3 DUF2666 PF10869.8 GBG62061.1 - 0.044 14.0 5.5 1.9 8.7 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) MotA_activ PF09114.10 GBG62061.1 - 0.051 13.7 0.7 3.5 7.8 0.1 2.1 1 1 0 2 2 2 0 Transcription factor MotA, activation domain RTX_C PF08339.10 GBG62061.1 - 0.054 13.6 1.4 3.4 7.7 0.1 2.2 1 1 0 2 2 2 0 RTX C-terminal domain Stirrup PF09061.6 GBG62061.1 - 0.061 13.5 0.3 8.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Stirrup HU-DNA_bdg PF14848.6 GBG62061.1 - 0.064 13.3 3.0 0.76 9.8 0.4 2.7 1 1 2 3 3 3 0 DNA-binding domain Toprim_2 PF13155.6 GBG62061.1 - 0.067 13.6 2.4 2.2 8.8 0.1 3.0 1 1 2 3 3 3 0 Toprim-like HipA_C PF07804.12 GBG62061.1 - 0.097 12.4 0.2 2.4 7.8 0.1 2.0 2 0 0 2 2 2 0 HipA-like C-terminal domain DUF1636 PF07845.11 GBG62061.1 - 0.14 12.6 0.0 19 5.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1636) DUF3016 PF11454.8 GBG62061.1 - 0.14 11.9 1.5 8.6 6.1 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3016) DUF1456 PF07308.13 GBG62061.1 - 0.16 12.4 5.9 0.69 10.3 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) RNA_pol_Rpb4 PF03874.16 GBG62061.1 - 0.17 12.2 3.2 1.5 9.2 0.5 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 MecA_N PF05223.11 GBG62061.1 - 0.18 12.1 3.8 0.32 11.3 0.6 2.0 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain DUF1007 PF06226.13 GBG62061.1 - 0.34 10.9 2.0 15 5.4 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1007) FDX-ACB PF03147.14 GBG62061.1 - 0.36 11.3 2.9 20 5.7 0.1 3.1 1 1 1 3 3 3 0 Ferredoxin-fold anticodon binding domain Fe_hyd_lg_C PF02906.14 GBG62061.1 - 0.48 10.1 4.5 2.5 7.7 4.5 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MgtE_N PF03448.17 GBG62061.1 - 2.5 8.7 6.9 9.7 6.9 2.8 2.1 1 1 1 2 2 2 0 MgtE intracellular N domain Mst1_SARAH PF11629.8 GBG62061.1 - 4 7.6 7.6 1.5 9.0 0.5 3.0 4 0 0 4 4 2 0 C terminal SARAH domain of Mst1 Retrotrans_gag PF03732.17 GBG62062.1 - 0.0012 19.0 0.1 0.0012 19.0 0.1 3.0 2 1 0 2 2 2 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG62062.1 - 0.18 12.3 2.5 1.5 9.4 0.1 3.5 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Sel1 PF08238.12 GBG62063.1 - 9e-15 54.8 8.5 2.4e-09 37.6 0.1 3.8 3 0 0 3 3 3 2 Sel1 repeat F-box PF00646.33 GBG62063.1 - 4.1e-09 36.1 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG62063.1 - 6.4e-07 29.2 0.2 1.4e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like NGP1NT PF08153.12 GBG62064.1 - 1.1e-18 67.7 6.2 9.2e-10 38.8 0.0 2.9 2 1 1 3 3 3 2 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 GBG62064.1 - 2.9e-16 59.6 0.0 1.1e-13 51.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG62064.1 - 1.5e-05 24.6 0.1 0.0001 21.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GBG62064.1 - 0.00057 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 GBG62064.1 - 0.016 14.7 0.1 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 GBG62064.1 - 0.094 12.9 0.0 18 5.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 GBG62064.1 - 0.11 12.3 0.9 9.1 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GBG62064.1 - 0.15 12.4 0.5 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain CDP-OH_P_transf PF01066.21 GBG62065.1 - 1.7e-18 67.1 0.0 1.7e-18 67.1 0.0 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GPCR_chapero_1 PF11904.8 GBG62066.1 - 0.065 12.7 8.6 0.12 11.7 8.6 1.4 1 0 0 1 1 1 0 GPCR-chaperone Presenilin PF01080.17 GBG62066.1 - 8.3 5.1 14.8 12 4.5 14.8 1.3 1 0 0 1 1 1 0 Presenilin DUF829 PF05705.14 GBG62067.1 - 4.5e-56 190.4 0.0 8.3e-56 189.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) IlvC PF01450.19 GBG62069.1 - 7e-50 169.1 5.0 5.7e-26 91.5 0.1 3.7 3 1 1 4 4 4 3 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 GBG62069.1 - 3.8e-31 107.9 0.0 7.9e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 GBG62069.1 - 0.061 13.9 0.4 0.48 11.0 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent G0-G1_switch_2 PF15103.6 GBG62069.1 - 0.088 13.2 0.1 14 6.1 0.0 2.6 1 1 1 2 2 2 0 G0/G1 switch protein 2 NiFe_hyd_3_EhaA PF17367.2 GBG62069.1 - 0.088 13.0 0.0 6.2 7.0 0.0 2.6 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A Pestivirus_E2 PF16329.5 GBG62069.1 - 0.19 10.5 0.0 0.38 9.5 0.0 1.4 1 0 0 1 1 1 0 Pestivirus envelope glycoprotein E2 IlvC PF01450.19 GBG62070.1 - 1.5e-43 148.6 2.9 3.8e-33 114.8 0.3 2.8 3 0 0 3 3 3 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 GBG62070.1 - 3.3e-31 108.1 0.0 7e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 GBG62070.1 - 0.054 14.1 0.3 0.42 11.2 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pestivirus_E2 PF16329.5 GBG62070.1 - 0.18 10.6 0.0 0.35 9.7 0.0 1.4 1 0 0 1 1 1 0 Pestivirus envelope glycoprotein E2 RT_RNaseH PF17917.1 GBG62071.1 - 2.2e-23 82.5 0.0 3e-22 78.9 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62071.1 - 1.4e-22 79.6 0.0 2.6e-21 75.5 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62071.1 - 3.3e-08 33.3 0.0 5.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62071.1 - 9.8e-08 32.0 0.7 1.9e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain GST_N_3 PF13417.6 GBG62072.1 - 9.9e-14 51.5 0.0 2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GBG62072.1 - 2.4e-11 43.6 0.4 5e-11 42.7 0.4 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 GBG62072.1 - 1.1e-08 35.7 0.0 2.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 GBG62072.1 - 2.1e-08 34.4 0.0 4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GBG62072.1 - 0.00057 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GBG62072.1 - 0.00084 19.3 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GBG62072.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GBG62072.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pex26 PF07163.12 GBG62072.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Pex26 protein DUF836 PF05768.14 GBG62072.1 - 0.18 12.2 0.1 0.32 11.4 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Prefoldin_2 PF01920.20 GBG62073.1 - 0.029 14.3 10.1 0.17 11.9 0.3 3.4 3 0 0 3 3 3 0 Prefoldin subunit MCU PF04678.13 GBG62073.1 - 0.26 11.4 3.2 0.2 11.8 0.5 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter LMBR1 PF04791.16 GBG62073.1 - 4.3 6.1 4.1 1.9 7.3 0.8 1.8 1 1 1 2 2 2 0 LMBR1-like membrane protein Actin PF00022.19 GBG62074.1 - 4.8e-77 259.3 0.0 1.4e-41 142.5 0.0 2.2 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 GBG62074.1 - 6.7e-05 21.9 0.0 0.17 10.6 0.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein GRP PF07172.11 GBG62074.1 - 9.9 6.9 26.4 0.88 10.3 9.2 2.4 2 0 0 2 2 2 0 Glycine rich protein family Kinesin PF00225.23 GBG62076.1 - 3.6e-109 364.7 0.0 9e-109 363.4 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG62076.1 - 1e-46 158.6 0.0 2e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF4358 PF14270.6 GBG62076.1 - 0.046 14.0 5.3 0.068 13.5 2.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Exonuc_VII_L PF02601.15 GBG62076.1 - 2.1 7.8 23.5 0.054 13.1 6.4 2.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit CTV_P6 PF06706.11 GBG62077.1 - 0.083 12.6 0.2 0.5 10.1 0.1 2.1 1 1 1 2 2 2 0 Citrus tristeza virus 6-kDa protein DUF543 PF04418.12 GBG62078.1 - 9.2e-23 80.0 0.0 1.3e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF4392 PF14336.6 GBG62079.1 - 0.023 14.1 1.2 0.062 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Alanine_zipper PF11839.8 GBG62079.1 - 0.27 11.6 28.0 0.031 14.6 22.5 2.3 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Per1 PF04080.13 GBG62080.1 - 3.8e-80 269.3 7.6 4.6e-80 269.1 7.6 1.1 1 0 0 1 1 1 1 Per1-like family Vanabin-2 PF11437.8 GBG62080.1 - 0.23 11.6 5.3 1.8 8.8 1.2 2.2 2 0 0 2 2 2 0 Vanadium-binding protein 2 TIL PF01826.17 GBG62080.1 - 0.26 11.6 6.5 0.12 12.6 1.0 2.2 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain zf-CCCH PF00642.24 GBG62082.1 - 9.2e-41 137.0 53.4 1e-09 38.1 5.3 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG62082.1 - 1.1e-17 63.4 64.7 9.8e-05 22.3 7.5 5.5 5 0 0 5 5 5 5 Zinc finger domain zf-CCCH_4 PF18044.1 GBG62082.1 - 3.9e-11 42.5 54.8 0.00023 20.9 5.0 5.4 5 0 0 5 5 5 5 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GBG62082.1 - 1.7e-05 25.1 48.9 0.34 11.5 3.1 5.7 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GBG62082.1 - 0.0019 18.9 29.2 1 10.1 0.1 5.3 4 1 1 5 5 5 3 Torus domain Integrase_H2C2 PF17921.1 GBG62083.1 - 6.4e-20 71.0 0.1 1.1e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG62083.1 - 4e-19 68.8 0.2 1.1e-18 67.4 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62083.1 - 5.7e-11 42.3 0.0 1.4e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG62083.1 - 0.00059 20.0 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG62083.1 - 0.02 15.1 0.5 0.087 13.1 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein rve PF00665.26 GBG62083.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Glyco_hydro_42C PF08533.10 GBG62085.1 - 0.007 16.1 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Beta-galactosidase C-terminal domain DUF3152 PF11350.8 GBG62085.1 - 0.078 12.7 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) DUF4187 PF13821.6 GBG62086.1 - 0.0086 15.8 0.7 0.031 14.1 0.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG62086.1 - 0.01 16.1 3.2 0.031 14.6 0.0 3.1 3 1 0 3 3 3 0 Retrotransposon gag protein FAM76 PF16046.5 GBG62086.1 - 0.54 9.6 11.2 1.1 8.5 11.2 1.7 1 0 0 1 1 1 0 FAM76 protein RVT_1 PF00078.27 GBG62088.1 - 1.7e-55 188.0 0.6 7.9e-29 100.8 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62088.1 - 4e-20 71.7 0.0 1.5e-18 66.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62088.1 - 1.6e-07 31.6 0.0 4.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ATG16 PF08614.11 GBG62088.1 - 0.081 13.1 1.3 0.18 12.0 1.3 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Wyosine_form PF08608.12 GBG62088.1 - 0.14 12.6 0.0 27 5.2 0.0 2.8 2 0 0 2 2 2 0 Wyosine base formation HSNSD PF12062.8 GBG62088.1 - 0.35 9.6 1.2 15 4.1 0.1 2.1 2 0 0 2 2 2 0 heparan sulfate-N-deacetylase YabA PF06156.13 GBG62088.1 - 2.2 9.0 5.3 0.38 11.4 0.1 2.4 3 0 0 3 3 3 0 Initiation control protein YabA APG17 PF04108.12 GBG62088.1 - 2.7 7.0 5.2 33 3.4 0.2 3.0 3 0 0 3 3 3 0 Autophagy protein Apg17 PHC2_SAM_assoc PF16616.5 GBG62089.1 - 0.7 10.7 18.9 0.22 12.3 13.7 2.7 2 1 1 3 3 3 0 Unstructured region on Polyhomeotic-like protein 1 and 2 EGF PF00008.27 GBG62090.1 - 0.00081 19.6 23.0 0.049 13.9 8.2 2.4 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 GBG62090.1 - 0.0014 19.0 24.9 0.045 14.1 7.7 2.7 2 2 0 2 2 2 2 EGF-like domain stn_TNFRSF12A PF12191.8 GBG62090.1 - 0.037 14.3 0.1 0.094 12.9 0.0 1.6 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain hEGF PF12661.7 GBG62090.1 - 0.044 14.4 15.8 0.26 12.0 4.0 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF NTF2 PF02136.20 GBG62091.1 - 1.4e-35 122.5 0.2 1.6e-35 122.3 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 GBG62091.1 - 0.0015 17.8 0.8 0.0042 16.3 0.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) SnoaL_2 PF12680.7 GBG62091.1 - 0.028 15.1 0.0 0.034 14.8 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 GBG62091.1 - 0.096 13.1 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) CPSF_A PF03178.15 GBG62092.1 - 3e-82 276.5 0.0 4.7e-82 275.9 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 GBG62092.1 - 4.5e-34 117.9 0.0 7.7e-33 113.9 0.0 2.3 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Adeno_shaft PF00608.17 GBG62092.1 - 0.12 12.2 0.4 0.29 11.0 0.4 1.6 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) eIF-5_eIF-2B PF01873.17 GBG62093.1 - 1.6e-36 124.7 0.0 3.2e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 GBG62093.1 - 4.9e-18 65.1 1.6 2.3e-17 62.9 0.3 2.7 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon YABBY PF04690.13 GBG62093.1 - 0.064 13.8 0.2 0.064 13.8 0.2 2.2 2 0 0 2 2 2 0 YABBY protein SSTK-IP PF15836.5 GBG62093.1 - 0.099 12.8 0.9 0.2 11.8 0.9 1.5 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein YxiJ PF14176.6 GBG62094.1 - 0.19 12.2 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 YxiJ-like protein DUF4407 PF14362.6 GBG62094.1 - 0.31 10.4 7.4 0.49 9.7 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Viral_P18 PF04521.13 GBG62094.1 - 0.82 9.5 3.5 0.26 11.1 0.8 1.6 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein RRM_1 PF00076.22 GBG62095.1 - 2.3e-35 120.2 0.0 9.8e-17 60.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG62095.1 - 5.6e-07 29.3 0.0 0.016 15.0 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 GBG62095.1 - 8.6e-07 29.0 0.0 0.0019 18.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Plavaka PF18759.1 GBG62096.1 - 4.9e-20 72.0 0.3 9.6e-20 71.0 0.3 1.4 1 0 0 1 1 1 1 Plavaka transposase Histone PF00125.24 GBG62096.1 - 2.8e-18 66.6 0.0 2.8e-18 66.6 0.0 3.0 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 RRM_1 PF00076.22 GBG62099.1 - 4.9e-33 112.8 0.1 3.9e-16 58.6 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) gag-asp_proteas PF13975.6 GBG62099.1 - 2.7e-06 27.9 0.0 7.8e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RRM_7 PF16367.5 GBG62099.1 - 9.3e-06 25.7 0.0 0.0077 16.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 GBG62099.1 - 1.3e-05 25.0 0.0 0.1 12.5 0.0 3.6 4 0 0 4 4 4 2 Occluded RNA-recognition motif Asp_protease_2 PF13650.6 GBG62099.1 - 0.00025 21.6 0.0 0.00073 20.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62099.1 - 0.0055 16.5 0.8 0.011 15.5 0.8 1.4 1 0 0 1 1 1 1 Aspartyl protease RRM_1 PF00076.22 GBG62100.1 - 4.9e-33 112.8 0.1 3.9e-16 58.6 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) gag-asp_proteas PF13975.6 GBG62100.1 - 2.7e-06 27.8 0.0 7.8e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RRM_7 PF16367.5 GBG62100.1 - 9.3e-06 25.7 0.0 0.0077 16.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 GBG62100.1 - 1.3e-05 25.0 0.0 0.1 12.5 0.0 3.6 4 0 0 4 4 4 2 Occluded RNA-recognition motif Asp_protease_2 PF13650.6 GBG62100.1 - 0.00025 21.6 0.0 0.00073 20.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62100.1 - 0.0054 16.5 0.8 0.011 15.5 0.8 1.4 1 0 0 1 1 1 1 Aspartyl protease RRM_1 PF00076.22 GBG62101.1 - 1.5e-33 114.4 0.0 9.2e-17 60.6 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG62101.1 - 7e-07 29.3 0.0 0.00081 19.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 GBG62101.1 - 0.00018 21.3 0.0 0.032 14.1 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF1866 PF08952.11 GBG62101.1 - 0.2 11.5 0.0 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_1 PF00076.22 GBG62102.1 - 1.6e-33 114.4 0.0 9.2e-17 60.6 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG62102.1 - 7e-07 29.3 0.0 0.00081 19.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 GBG62102.1 - 0.00018 21.3 0.0 0.032 14.1 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF1866 PF08952.11 GBG62102.1 - 0.2 11.5 0.0 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_1 PF00076.22 GBG62103.1 - 1.7e-33 114.3 0.0 9.4e-17 60.6 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG62103.1 - 7.3e-07 29.2 0.0 0.00083 19.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 GBG62103.1 - 0.00019 21.3 0.0 0.033 14.1 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF1866 PF08952.11 GBG62103.1 - 0.2 11.5 0.0 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Apt1 PF10351.9 GBG62103.1 - 0.87 8.4 6.4 1.3 7.8 6.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRM_1 PF00076.22 GBG62104.1 - 1.6e-33 114.4 0.0 9.2e-17 60.6 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG62104.1 - 7e-07 29.3 0.0 0.00082 19.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 GBG62104.1 - 0.00018 21.3 0.0 0.032 14.1 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF1866 PF08952.11 GBG62104.1 - 0.2 11.5 0.0 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) AMP-binding PF00501.28 GBG62105.1 - 4.5e-39 134.2 0.0 6.6e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GBG62105.1 - 2.4e-06 28.4 0.1 2.4e-06 28.4 0.1 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Ifi-6-16 PF06140.13 GBG62105.1 - 2.6 8.0 6.7 0.16 11.9 0.7 2.1 2 0 0 2 2 2 0 Interferon-induced 6-16 family tRNA-synt_1_2 PF13603.6 GBG62106.1 - 0.11 12.0 2.1 0.13 11.8 0.8 1.7 1 1 1 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 BAF1_ABF1 PF04684.13 GBG62106.1 - 0.62 9.1 16.8 0.8 8.7 16.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RVT_1 PF00078.27 GBG62107.1 - 1.7e-27 96.4 0.0 2.8e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62107.1 - 3.9e-22 78.5 0.1 9.2e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62107.1 - 3.8e-16 59.0 1.2 1.1e-15 57.5 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG62107.1 - 1.9e-12 47.1 0.0 4.6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62107.1 - 3.5e-12 46.6 0.1 1.6e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG62107.1 - 2.4e-11 43.4 0.0 5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG62107.1 - 2.6e-05 24.3 0.0 5.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG62107.1 - 0.15 11.8 0.1 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like Ist1 PF03398.14 GBG62108.1 - 3.8e-51 173.3 1.5 2.4e-47 160.9 3.0 2.7 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway Retrotrans_gag PF03732.17 GBG62108.1 - 1.9e-06 28.1 2.7 0.031 14.5 0.1 3.5 4 0 0 4 4 4 2 Retrotransposon gag protein CENP-K PF11802.8 GBG62108.1 - 0.012 15.2 5.4 0.016 14.8 4.1 1.7 2 0 0 2 2 2 0 Centromere-associated protein K TMEM247 PF15444.6 GBG62108.1 - 0.37 10.8 5.2 0.17 11.9 0.1 2.6 2 0 0 2 2 2 0 Transmembrane protein 247 Agenet PF05641.12 GBG62109.1 - 5.4e-18 65.2 7.2 6.7e-14 52.1 0.6 3.1 2 0 0 2 2 2 2 Agenet domain AT_hook PF02178.19 GBG62109.1 - 0.028 14.2 3.9 0.27 11.2 3.9 2.9 1 0 0 1 1 1 0 AT hook motif SpoVR PF04293.13 GBG62111.1 - 0.61 8.7 10.0 1.2 7.8 10.0 1.4 1 0 0 1 1 1 0 SpoVR like protein Plasmodium_Vir PF05795.11 GBG62111.1 - 0.79 9.1 6.4 1.3 8.4 6.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NEMP PF10225.9 GBG62111.1 - 2.3 7.8 4.6 4.1 7.0 4.6 1.4 1 0 0 1 1 1 0 NEMP family Pkinase PF00069.25 GBG62112.1 - 4.2e-65 219.7 0.1 5.2e-65 219.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG62112.1 - 6.8e-17 61.6 0.0 9.3e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG62112.1 - 2.7e-07 30.8 0.0 6.7e-06 26.2 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG62112.1 - 0.0081 15.0 0.0 0.015 14.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GBG62112.1 - 0.023 14.1 0.5 0.048 13.0 0.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GBG62112.1 - 0.034 13.7 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 GBG62113.1 - 4.2e-65 219.7 0.1 5.3e-65 219.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG62113.1 - 6.8e-17 61.6 0.0 9.4e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG62113.1 - 2.6e-07 30.8 0.0 6.7e-06 26.2 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG62113.1 - 0.0081 15.0 0.0 0.015 14.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GBG62113.1 - 0.023 14.1 0.5 0.049 13.0 0.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GBG62113.1 - 0.034 13.7 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Raf1_N PF18578.1 GBG62114.1 - 7.7e-33 113.2 2.5 1.2e-32 112.5 2.5 1.3 1 0 0 1 1 1 1 Rubisco accumulation factor 1 alpha helical domain Raf1_HTH PF18579.1 GBG62114.1 - 5.8e-21 74.0 0.0 1.2e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain RuBisCo_chap_C PF18087.1 GBG62114.1 - 8.6e-17 61.1 0.4 1.2e-16 60.6 0.4 1.2 1 0 0 1 1 1 1 Rubisco Assembly chaperone C-terminal domain RPS31 PF17067.5 GBG62114.1 - 0.052 13.7 7.2 0.16 12.2 7.2 1.9 1 0 0 1 1 1 0 Ribosomal protein S31e Fer2 PF00111.27 GBG62117.1 - 3.4e-14 52.5 0.2 6.4e-14 51.7 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAM176 PF14851.6 GBG62118.1 - 0.00015 21.4 1.1 0.00015 21.4 1.1 3.0 1 1 1 2 2 1 1 FAM176 family Orf78 PF06024.12 GBG62118.1 - 0.0027 18.0 0.6 0.0027 18.0 0.6 2.6 2 1 0 2 2 2 1 Orf78 (ac78) DUF898 PF05987.13 GBG62118.1 - 0.017 14.2 0.1 0.027 13.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) BUD22 PF09073.10 GBG62118.1 - 0.021 14.2 24.5 0.029 13.7 24.5 1.2 1 0 0 1 1 1 0 BUD22 V_ATPase_I PF01496.19 GBG62118.1 - 0.022 12.7 0.1 0.022 12.7 0.1 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Afaf PF15339.6 GBG62118.1 - 0.027 14.2 0.2 0.037 13.7 0.2 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF2417 PF10329.9 GBG62118.1 - 0.029 13.8 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) SID-1_RNA_chan PF13965.6 GBG62118.1 - 0.043 12.2 0.1 0.043 12.2 0.1 1.6 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 DUF2615 PF11027.8 GBG62118.1 - 0.046 13.8 1.0 0.046 13.8 1.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2615) Pex24p PF06398.11 GBG62118.1 - 0.052 12.5 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF4448 PF14610.6 GBG62118.1 - 0.053 13.3 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4834 PF16118.5 GBG62118.1 - 0.056 14.4 0.0 0.41 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Connexin PF00029.19 GBG62118.1 - 0.15 11.8 1.0 0.99 9.1 0.2 2.0 1 1 1 2 2 2 0 Connexin DUF3402 PF11882.8 GBG62118.1 - 0.21 10.7 3.7 0.26 10.4 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Trypan_PARP PF05887.11 GBG62118.1 - 0.23 11.4 2.7 4.4 7.3 1.7 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Myc_N PF01056.18 GBG62118.1 - 0.3 11.0 9.2 3.9 7.3 0.1 2.2 2 0 0 2 2 2 0 Myc amino-terminal region DUF2457 PF10446.9 GBG62118.1 - 1.2 8.2 59.3 0.066 12.3 27.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) GEN1_C PF18380.1 GBG62118.1 - 1.7 9.6 12.6 0.37 11.7 2.1 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Zip PF02535.22 GBG62118.1 - 2.7 7.1 8.8 1.3 8.2 0.2 2.0 1 1 1 2 2 2 0 ZIP Zinc transporter Ac81 PF05820.11 GBG62118.1 - 3.8 7.0 6.3 6.1 6.4 6.3 1.3 1 0 0 1 1 1 0 Baculoviridae AC81 Cyt-b5 PF00173.28 GBG62120.1 - 1.5e-10 41.1 0.0 3.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.26 GBG62121.1 - 3.4e-08 33.7 0.0 6.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain PTCB-BRCT PF12738.7 GBG62121.1 - 0.00021 21.2 0.1 0.00034 20.5 0.1 1.4 1 0 0 1 1 1 1 twin BRCT domain Yop-YscD_cpl PF16697.5 GBG62121.1 - 0.02 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RT_RNaseH_2 PF17919.1 GBG62122.1 - 1.3e-31 108.6 0.2 5e-31 106.7 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62122.1 - 6.4e-27 93.9 0.2 1.7e-26 92.6 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mcp5_PH PF12814.7 GBG62122.1 - 0.04 14.0 0.6 0.096 12.8 0.6 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Nbs1_C PF08599.10 GBG62122.1 - 0.044 13.9 3.6 2.4 8.3 1.3 2.6 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Myb_DNA-bind_4 PF13837.6 GBG62124.1 - 0.0047 17.3 0.1 0.18 12.2 0.1 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MAD PF05557.13 GBG62124.1 - 0.57 8.5 1.4 0.8 8.0 1.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein RVT_1 PF00078.27 GBG62125.1 - 1.2e-31 110.0 0.0 2e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62126.1 - 6.4e-30 103.1 0.0 1.5e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62126.1 - 1.5e-26 93.3 0.1 2.3e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62126.1 - 3.9e-26 91.4 0.0 7.4e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG62126.1 - 3.6e-05 24.1 0.3 0.00011 22.5 0.3 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG62126.1 - 0.0054 16.8 0.2 0.013 15.5 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG62126.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Shisa PF13908.6 GBG62127.1 - 0.0056 16.9 1.6 1.4 9.1 0.0 2.9 2 1 0 2 2 2 2 Wnt and FGF inhibitory regulator Tweety PF04906.13 GBG62127.1 - 0.027 13.1 25.8 0.0053 15.5 18.7 2.5 2 1 0 2 2 2 0 Tweety Myc_target_1 PF15179.6 GBG62127.1 - 0.064 13.2 0.6 0.15 11.9 0.6 1.6 1 0 0 1 1 1 0 Myc target protein 1 Adeno_E3_CR2 PF02439.15 GBG62127.1 - 0.08 12.7 17.4 0.085 12.6 1.4 2.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Phage_holin_3_6 PF07332.11 GBG62127.1 - 0.23 11.5 12.0 2.1 8.4 3.4 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 GBG62127.1 - 0.69 8.6 12.6 0.036 12.8 1.4 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) EI24 PF07264.11 GBG62127.1 - 1.4 9.2 12.0 2 8.6 4.4 2.4 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) RVT_1 PF00078.27 GBG62129.1 - 4.5e-21 75.4 0.0 3.5e-19 69.2 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG62129.1 - 0.0091 15.5 9.6 0.021 14.3 9.6 1.6 1 0 0 1 1 1 1 SDA1 NOA36 PF06524.12 GBG62129.1 - 1 8.6 13.3 2.5 7.4 13.3 1.6 1 0 0 1 1 1 0 NOA36 protein TPR_14 PF13428.6 GBG62129.1 - 1.2 10.2 4.3 30 5.8 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop14 PF04147.12 GBG62129.1 - 1.2 7.3 13.7 1.9 6.6 13.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG62129.1 - 1.3 7.2 8.8 2.8 6.1 8.8 1.5 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 GBG62129.1 - 1.6 8.6 7.4 2.8 7.8 7.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sigma70_ner PF04546.13 GBG62129.1 - 2.2 8.1 13.4 3.7 7.4 12.1 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region XAP5 PF04921.14 GBG62129.1 - 2.4 7.9 8.0 4.3 7.1 8.0 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator RNA_polI_A34 PF08208.11 GBG62129.1 - 3 7.9 8.4 5.9 6.9 8.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DNA_pol_phi PF04931.13 GBG62129.1 - 3.5 5.6 15.2 6.4 4.7 15.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 GBG62129.1 - 4.5 6.4 8.8 8.1 5.6 8.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HSP90 PF00183.18 GBG62129.1 - 9.5 5.0 9.5 15 4.3 9.5 1.2 1 0 0 1 1 1 0 Hsp90 protein F-box-like PF12937.7 GBG62130.1 - 8.7e-08 31.9 0.8 8.7e-08 31.9 0.8 2.8 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GBG62130.1 - 2e-07 31.2 3.4 15 6.2 0.0 6.1 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG62130.1 - 1.6e-06 27.8 0.1 1.6e-06 27.8 0.1 3.3 5 0 0 5 5 5 1 F-box domain LRR_6 PF13516.6 GBG62130.1 - 5.7e-05 22.8 7.7 0.51 10.5 0.1 7.3 9 0 0 9 9 9 1 Leucine Rich repeat Spt5_N PF11942.8 GBG62130.1 - 0.044 14.8 4.3 1.5 9.8 0.2 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Zn_ribbon_SprT PF17283.2 GBG62130.1 - 0.1 12.5 2.7 0.37 10.7 2.7 2.0 1 0 0 1 1 1 0 SprT-like zinc ribbon domain LRR_1 PF00560.33 GBG62130.1 - 8.7 7.3 16.7 1e+02 4.1 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat ORF6C PF10552.9 GBG62131.1 - 8.1e-05 22.7 1.0 0.82 9.8 0.0 3.3 4 0 0 4 4 4 2 ORF6C domain Cyt-b5 PF00173.28 GBG62131.1 - 0.0056 16.8 0.0 5.9 7.1 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain ComC PF03047.14 GBG62131.1 - 0.097 12.5 0.2 39 4.2 0.0 3.4 2 0 0 2 2 2 0 COMC family SRP-alpha_N PF04086.13 GBG62131.1 - 0.29 11.0 20.2 0.38 10.6 8.9 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal zf-BED PF02892.15 GBG62131.1 - 0.43 10.6 2.9 21 5.2 0.2 2.4 2 0 0 2 2 2 0 BED zinc finger Gag_p17 PF00540.18 GBG62131.1 - 0.75 9.8 8.4 8.5 6.4 1.1 2.9 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) Zn_ribbon_SprT PF17283.2 GBG62131.1 - 1.2 9.1 3.9 24 4.9 0.3 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DNA_pol_phi PF04931.13 GBG62131.1 - 2.9 5.9 0.0 2.9 5.9 0.0 2.5 3 0 0 3 3 3 0 DNA polymerase phi RRM_1 PF00076.22 GBG62133.1 - 2.8e-19 68.7 0.0 5.5e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 GBG62133.1 - 7.3e-06 25.8 3.7 1.6e-05 24.7 3.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GBG62133.1 - 4e-05 24.3 0.4 4e-05 24.3 0.4 3.4 4 1 0 4 4 4 1 Torus domain RRM_7 PF16367.5 GBG62133.1 - 4.6e-05 23.5 0.0 0.00015 21.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif zf_CCCH_4 PF18345.1 GBG62133.1 - 0.0041 17.1 7.0 0.01 15.9 7.0 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 GBG62133.1 - 0.021 14.6 4.3 0.049 13.5 4.3 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger ABC_tran PF00005.27 GBG62134.1 - 2.3e-54 183.6 0.0 6.8e-30 104.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GBG62134.1 - 8.6e-45 153.5 20.5 3.9e-32 112.0 7.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GBG62134.1 - 5.5e-11 42.3 2.6 0.0006 19.3 0.8 4.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GBG62134.1 - 3.4e-07 29.9 0.8 0.036 13.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GBG62134.1 - 4.4e-06 26.7 0.6 0.014 15.3 0.3 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GBG62134.1 - 6.2e-06 26.3 4.9 0.023 14.7 0.0 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase SDA1 PF05285.12 GBG62134.1 - 1e-05 25.2 8.0 1e-05 25.2 8.0 1.6 2 0 0 2 2 2 1 SDA1 AAA_21 PF13304.6 GBG62134.1 - 6.5e-05 22.9 0.0 1.4 8.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system CDC45 PF02724.14 GBG62134.1 - 0.00015 20.3 3.1 0.00015 20.3 3.1 1.8 2 0 0 2 2 2 1 CDC45-like protein AAA_22 PF13401.6 GBG62134.1 - 0.00034 20.9 0.5 0.99 9.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 GBG62134.1 - 0.00041 19.4 0.6 0.071 12.1 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 GBG62134.1 - 0.00067 19.8 2.9 0.075 13.1 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain Tim54 PF11711.8 GBG62134.1 - 0.00084 18.2 3.8 0.0017 17.2 3.8 1.5 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 AAA_30 PF13604.6 GBG62134.1 - 0.0029 17.3 3.1 0.38 10.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GBG62134.1 - 0.0034 17.8 5.6 2 8.8 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain Presenilin PF01080.17 GBG62134.1 - 0.0062 15.4 0.6 0.013 14.3 0.6 1.5 1 0 0 1 1 1 1 Presenilin NB-ARC PF00931.22 GBG62134.1 - 0.0063 15.7 2.5 0.94 8.6 0.4 2.7 3 0 0 3 3 2 1 NB-ARC domain DUF4337 PF14235.6 GBG62134.1 - 0.017 15.3 3.6 0.042 14.0 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) cobW PF02492.19 GBG62134.1 - 0.019 14.6 0.5 3.3 7.3 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 GBG62134.1 - 0.02 13.9 0.1 0.31 10.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 GBG62134.1 - 0.066 12.5 0.2 3.2 7.0 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 GBG62134.1 - 0.067 13.3 8.0 1.6 8.7 0.2 3.5 3 0 0 3 3 3 0 Dynamin family AAA PF00004.29 GBG62134.1 - 0.075 13.5 1.2 15 6.0 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.12 GBG62134.1 - 0.09 12.1 1.0 0.49 9.7 0.0 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region NTPase_1 PF03266.15 GBG62134.1 - 0.096 12.6 1.3 5.7 6.8 0.1 3.1 3 0 0 3 3 2 0 NTPase DUF815 PF05673.13 GBG62134.1 - 0.11 11.7 0.2 11 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 GBG62134.1 - 0.12 12.3 1.9 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 GBG62134.1 - 0.13 11.9 0.0 6.8 6.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 GBG62134.1 - 0.15 11.7 2.5 4.7 6.9 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein MobB PF03205.14 GBG62134.1 - 0.18 11.7 0.7 15 5.5 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2151 PF10221.9 GBG62134.1 - 0.19 10.3 2.0 0.28 9.8 2.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator ATP_bind_1 PF03029.17 GBG62134.1 - 0.2 11.4 0.9 14 5.4 0.4 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Plasmodium_Vir PF05795.11 GBG62134.1 - 0.9 8.9 3.0 0.45 9.9 0.6 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein NACHT PF05729.12 GBG62134.1 - 1.4 8.8 3.3 23 4.8 0.6 2.6 2 0 0 2 2 2 0 NACHT domain eIF-3c_N PF05470.12 GBG62134.1 - 1.6 6.9 14.8 2.7 6.2 14.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NPR3 PF03666.13 GBG62134.1 - 4.5 5.9 7.7 7.9 5.1 7.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 OAD_gamma PF04277.13 GBG62134.1 - 6.8 7.4 12.7 26 5.5 9.2 3.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Connexin PF00029.19 GBG62134.1 - 7.6 6.2 11.0 0.31 10.8 4.8 1.8 2 0 0 2 2 1 0 Connexin DNA_pol_phi PF04931.13 GBG62134.1 - 8.2 4.4 33.1 13 3.8 33.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi SpoIIP PF07454.11 GBG62134.1 - 10 5.5 12.1 0.38 10.2 6.0 1.6 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SNN_linker PF09050.10 GBG62135.1 - 0.031 14.1 4.1 1.2 9.0 0.1 3.7 3 0 0 3 3 3 0 Stannin unstructured linker Spt20 PF12090.8 GBG62136.1 - 0.037 13.7 4.7 0.064 12.9 4.7 1.3 1 0 0 1 1 1 0 Spt20 family AIF_C PF14721.6 GBG62136.1 - 0.095 13.1 1.1 0.8 10.1 0.7 2.5 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ABC_membrane PF00664.23 GBG62136.1 - 0.73 9.4 6.7 0.12 12.0 3.1 1.5 2 0 0 2 2 2 0 ABC transporter transmembrane region GRIP PF01465.20 GBG62136.1 - 0.9 9.5 2.9 26 4.8 0.1 2.5 2 0 0 2 2 2 0 GRIP domain DUF1761 PF08570.10 GBG62136.1 - 1.2 9.4 3.9 4.7 7.5 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) YppG PF14179.6 GBG62136.1 - 4.8 7.9 7.9 13 6.6 7.9 1.6 1 0 0 1 1 1 0 YppG-like protein ABC_membrane PF00664.23 GBG62137.1 - 0.061 13.0 3.1 0.094 12.4 3.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region Na_trans_assoc PF06512.13 GBG62139.1 - 0.86 9.8 13.2 1.1 9.4 13.2 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG62139.1 - 5.9 5.0 21.6 7.2 4.7 21.6 1.0 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG62139.1 - 9.2 5.7 10.1 13 5.2 10.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DivIC PF04977.15 GBG62140.1 - 2.8 7.8 7.9 0.12 12.2 1.4 2.1 2 0 0 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 GBG62140.1 - 5.2 7.4 9.4 0.56 10.5 0.6 2.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SQS_PSY PF00494.19 GBG62141.1 - 4.5e-71 239.4 1.1 7.3e-71 238.7 1.1 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase RVT_1 PF00078.27 GBG62143.1 - 1.3e-46 158.9 0.4 3.9e-28 98.5 0.1 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62143.1 - 1.3e-23 83.3 0.0 3.5e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62143.1 - 1.4e-23 82.8 0.0 2.6e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG62143.1 - 1.2e-15 57.7 0.0 2.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG62143.1 - 0.00021 21.0 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVP_2 PF08284.11 GBG62143.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Trypan_glycop_C PF10659.9 GBG62144.1 - 7.8 6.9 10.7 7.6 7.0 8.6 1.9 1 1 1 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain DUF659 PF04937.15 GBG62146.1 - 5.8e-13 49.0 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG62147.1 - 2.4e-06 28.0 0.1 5.7e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62147.1 - 0.00021 21.9 0.0 0.00062 20.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62147.1 - 0.00038 20.3 0.1 0.00061 19.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG62147.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Spem1 PF15670.5 GBG62148.1 - 8.4 5.9 26.8 16 5.0 24.5 2.4 2 0 0 2 2 2 0 Spermatid maturation protein 1 bZIP_1 PF00170.21 GBG62149.1 - 2e-12 47.0 15.7 1.2e-11 44.5 10.6 2.4 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GBG62149.1 - 4.5e-07 29.9 22.0 2.4e-06 27.5 13.8 2.8 2 1 1 3 3 3 2 Basic region leucine zipper Cep57_CLD_2 PF14197.6 GBG62149.1 - 0.011 15.8 6.5 0.011 15.8 6.5 2.3 2 1 2 4 4 3 0 Centrosome localisation domain of PPC89 Mito_fiss_reg PF05308.11 GBG62149.1 - 0.015 15.4 16.6 0.019 15.0 1.9 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Atg14 PF10186.9 GBG62149.1 - 0.039 13.0 6.1 0.057 12.5 6.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 GBG62149.1 - 0.075 13.1 8.0 0.14 12.3 8.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMCO5 PF14992.6 GBG62149.1 - 0.08 12.5 6.1 0.13 11.9 6.1 1.2 1 0 0 1 1 1 0 TMCO5 family ApoO PF09769.9 GBG62149.1 - 0.61 10.0 3.9 3.3 7.7 0.3 2.4 1 1 1 2 2 2 0 Apolipoprotein O ADIP PF11559.8 GBG62149.1 - 0.87 9.7 13.1 1.8 8.6 13.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 GBG62149.1 - 1.5 6.6 6.1 2.3 6.1 6.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.17 GBG62149.1 - 2.3 8.8 21.8 0.046 14.2 14.8 1.8 2 1 0 2 2 1 0 bZIP Maf transcription factor YabA PF06156.13 GBG62149.1 - 2.5 8.8 11.8 0.79 10.4 2.1 2.4 1 1 1 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 GBG62149.1 - 6.2 7.8 18.2 5 8.1 8.0 2.7 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Pacifastin_I PF05375.13 GBG62150.1 - 0.00057 19.6 5.3 0.00057 19.6 5.3 3.5 2 1 1 3 3 3 1 Pacifastin inhibitor (LCMII) Hydrolase_4 PF12146.8 GBG62151.1 - 1.4e-58 198.0 0.0 2e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG62151.1 - 4.6e-10 39.6 0.0 4.3e-07 29.8 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG62151.1 - 1.2e-08 35.9 8.5 1.3e-08 35.7 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GBG62151.1 - 1.3e-07 31.3 0.0 0.00094 18.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 GBG62151.1 - 7.3e-06 24.9 0.0 0.0027 16.4 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 GBG62151.1 - 4.8e-05 23.3 0.0 0.053 13.3 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Esterase PF00756.20 GBG62151.1 - 0.00073 19.2 0.0 0.0019 17.9 0.0 1.8 2 0 0 2 2 2 1 Putative esterase DLH PF01738.18 GBG62151.1 - 0.0058 16.2 0.0 0.92 9.0 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 GBG62151.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 GBG62151.1 - 0.021 14.4 0.0 0.14 11.7 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1644 PF07800.12 GBG62151.1 - 0.036 14.1 0.0 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Abhydrolase_3 PF07859.13 GBG62151.1 - 0.065 13.1 0.0 0.38 10.6 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 GBG62151.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DP PF08781.10 GBG62151.1 - 0.22 11.4 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Transcription factor DP DUF2920 PF11144.8 GBG62151.1 - 0.3 10.2 0.0 1 8.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Hydrolase_4 PF12146.8 GBG62152.1 - 1.9e-58 197.6 0.0 2.2e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG62152.1 - 1.9e-09 38.4 0.0 2.4e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG62152.1 - 7.9e-09 35.5 0.0 5.1e-06 26.3 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GBG62152.1 - 2.2e-08 33.8 0.0 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GBG62152.1 - 6.2e-06 26.2 0.0 0.005 16.7 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 GBG62152.1 - 3.5e-05 22.6 0.0 0.023 13.4 0.0 2.3 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase PF00756.20 GBG62152.1 - 0.00032 20.4 0.0 0.00041 20.1 0.0 1.4 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 GBG62152.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 GBG62152.1 - 0.003 17.2 0.0 0.029 14.0 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 GBG62152.1 - 0.0092 15.9 0.0 0.17 11.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 GBG62152.1 - 0.011 15.4 0.1 0.067 12.7 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family Clc-like PF07062.12 GBG62152.1 - 0.25 10.8 0.1 0.39 10.2 0.1 1.2 1 0 0 1 1 1 0 Clc-like FTHFS PF01268.19 GBG62154.1 - 4.8e-255 847.0 0.0 5.5e-255 846.8 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase RT_RNaseH_2 PF17919.1 GBG62156.1 - 2.5e-20 72.4 0.0 5.7e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62156.1 - 8.5e-18 64.2 0.1 2.1e-17 62.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG62156.1 - 4.3e-12 46.3 0.0 9.4e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62156.1 - 1e-09 38.3 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG62156.1 - 1.3e-09 38.2 0.0 3.7e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG62157.1 - 8.8e-34 117.0 0.1 1.5e-33 116.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62157.1 - 2.4e-06 27.6 0.0 7.3e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG62157.1 - 3.3e-06 26.9 0.0 7.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62157.1 - 3e-05 24.6 0.0 0.00045 20.8 0.0 2.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62157.1 - 0.00072 20.1 0.0 0.0025 18.3 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG62157.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease eIF-1a PF01176.19 GBG62157.1 - 0.049 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 zf-CCHC PF00098.23 GBG62157.1 - 0.17 12.0 0.8 0.31 11.2 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG62157.1 - 1.2 9.0 4.2 2.2 8.2 4.2 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG62158.1 - 3.4e-09 36.5 0.0 1.7e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) KIAA1430 PF13879.6 GBG62158.1 - 0.0085 16.8 0.0 0.0085 16.8 0.0 3.3 2 0 0 2 2 2 1 KIAA1430 homologue DUF4834 PF16118.5 GBG62161.1 - 0.11 13.4 0.3 0.41 11.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CFTR_R PF14396.6 GBG62161.1 - 0.25 10.9 0.1 0.25 10.9 0.1 1.8 2 0 0 2 2 2 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain CAF1 PF04857.20 GBG62162.1 - 6.2e-22 78.2 0.4 1.2e-10 41.1 0.0 2.8 2 1 0 2 2 2 2 CAF1 family ribonuclease RT_RNaseH_2 PF17919.1 GBG62163.1 - 4.4e-25 87.6 0.0 7.5e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62163.1 - 4.9e-19 68.5 0.0 9.7e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62163.1 - 2.6e-10 40.2 0.0 4.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG62163.1 - 1.4 8.3 10.0 2 7.8 10.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG62163.1 - 1.7 6.9 8.0 2.4 6.4 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG62163.1 - 1.9 6.6 9.4 2.6 6.1 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family peroxidase PF00141.23 GBG62164.1 - 1.7e-46 158.8 0.0 2.8e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF1206 PF06724.11 GBG62164.1 - 0.28 11.3 5.8 0.55 10.3 5.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) RVT_1 PF00078.27 GBG62165.1 - 1.3e-25 90.3 0.1 2.6e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG62165.1 - 4.6e-07 30.1 0.0 1.4e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG62165.1 - 0.00014 22.0 0.9 0.0058 16.9 0.1 3.6 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG62165.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Trypan_glycop_C PF10659.9 GBG62166.1 - 0.0062 16.9 0.3 0.0062 16.9 0.3 2.0 1 1 1 2 2 2 1 Trypanosome variant surface glycoprotein C-terminal domain DUF2058 PF09831.9 GBG62166.1 - 7.5 6.7 17.4 0.16 12.1 10.5 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) AAA PF00004.29 GBG62167.1 - 1.8e-41 141.7 0.1 3.7e-41 140.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG62167.1 - 1.1e-13 50.7 0.4 2.7e-13 49.5 0.4 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GBG62167.1 - 1.8e-10 40.6 0.3 4.9e-10 39.2 0.3 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 GBG62167.1 - 1.4e-07 31.6 0.4 1.2e-06 28.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG62167.1 - 5.8e-06 26.8 0.1 0.0015 19.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 GBG62167.1 - 3.4e-05 24.0 0.0 0.00012 22.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GBG62167.1 - 3.6e-05 23.5 0.0 0.0001 22.1 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG62167.1 - 0.00021 21.6 0.2 0.048 13.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 GBG62167.1 - 0.0039 16.4 0.0 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase PF06745.13 GBG62167.1 - 0.011 15.1 0.2 0.049 13.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 GBG62167.1 - 0.012 15.1 0.0 0.033 13.7 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 GBG62167.1 - 0.017 14.6 0.1 0.058 12.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 GBG62167.1 - 0.018 14.4 0.0 0.054 12.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GBG62167.1 - 0.031 14.0 0.1 0.1 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GBG62167.1 - 0.039 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 GBG62167.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG62167.1 - 0.075 13.6 0.0 0.31 11.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GBG62167.1 - 0.092 12.5 0.3 0.58 9.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GBG62167.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.9 2 1 0 2 2 1 0 Sigma-54 interaction domain CPT PF07931.12 GBG62167.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.6 GBG62167.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain JIP_LZII PF16471.5 GBG62167.1 - 0.14 12.3 3.8 0.36 11.0 3.8 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II RNA_helicase PF00910.22 GBG62167.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase PSI_8 PF00796.18 GBG62167.1 - 0.16 11.8 1.8 0.28 11.1 1.8 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII CCDC73 PF15818.5 GBG62167.1 - 0.83 7.4 6.2 1.1 7.0 6.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family RVT_1 PF00078.27 GBG62169.1 - 3e-38 131.6 0.0 5.3e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG62169.1 - 5.6e-06 27.0 4.4 1.9e-05 25.3 4.4 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase KH_7 PF17214.3 GBG62169.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 KH domain DUF4355 PF14265.6 GBG62169.1 - 1.1 9.6 4.4 2.3 8.5 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Glycos_transf_1 PF00534.20 GBG62170.1 - 2e-16 60.0 0.0 2.2e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG62170.1 - 2.8e-13 50.5 0.0 5.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG62170.1 - 6.2e-06 26.5 0.0 1.9e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycogen_syn PF05693.13 GBG62170.1 - 0.088 11.3 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase TPP_enzyme_N PF02776.18 GBG62171.1 - 6.8e-36 123.5 0.3 1.4e-35 122.4 0.3 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GBG62171.1 - 6.7e-22 77.7 0.0 1.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GBG62171.1 - 1.7e-19 70.1 0.0 3.4e-18 65.9 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 GBG62171.1 - 0.0018 18.1 0.1 0.0035 17.1 0.1 1.4 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit E1_dh PF00676.20 GBG62171.1 - 0.34 9.8 2.0 0.37 9.7 0.1 1.9 2 0 0 2 2 2 0 Dehydrogenase E1 component Rad51 PF08423.11 GBG62172.1 - 3.4e-49 167.4 1.1 7.9e-49 166.2 1.1 1.5 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GBG62172.1 - 7.3e-11 42.0 0.1 1.1e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GBG62172.1 - 1.6e-08 34.2 3.4 9.4e-08 31.7 3.4 1.9 1 1 0 1 1 1 1 KaiC RecA PF00154.21 GBG62172.1 - 0.0078 15.7 2.6 1.3 8.5 0.4 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_24 PF13479.6 GBG62172.1 - 0.01 15.5 0.0 0.046 13.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GBG62172.1 - 0.018 15.3 0.2 0.054 13.8 0.1 1.9 2 1 0 2 2 2 0 AAA domain Cdd1 PF11731.8 GBG62172.1 - 0.034 14.4 0.0 0.9 9.8 0.0 2.7 2 1 1 3 3 3 0 Pathogenicity locus Mob_synth_C PF06463.13 GBG62172.1 - 0.05 13.5 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C AAA_33 PF13671.6 GBG62172.1 - 0.063 13.4 0.5 0.39 10.9 0.5 2.3 1 1 0 1 1 1 0 AAA domain TPP_enzyme_M PF00205.22 GBG62174.1 - 1.8e-21 76.3 0.1 2.9e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 GBG62174.1 - 7.3e-14 51.7 0.3 1.5e-13 50.7 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Asparaginase PF00710.20 GBG62174.1 - 0.041 13.4 0.1 0.098 12.2 0.1 1.6 1 0 0 1 1 1 0 Asparaginase, N-terminal Y_phosphatase2 PF03162.13 GBG62175.1 - 6.8e-42 142.8 0.0 9.7e-42 142.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GBG62175.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Roughex PF06020.11 GBG62175.1 - 1.1 8.3 5.5 1.6 7.7 5.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF3987 PF13148.6 GBG62176.1 - 0.003 16.6 2.2 0.0053 15.8 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) zf-PHD-like PF15446.6 GBG62176.1 - 0.0071 16.0 0.7 0.012 15.3 0.7 1.3 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PIN_8 PF18476.1 GBG62176.1 - 0.21 11.4 4.4 0.27 11.1 3.4 1.5 1 1 1 2 2 2 0 PIN like domain FUSC PF04632.12 GBG62176.1 - 1.1 7.7 11.7 2.3 6.7 8.7 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family RT_RNaseH PF17917.1 GBG62177.1 - 3.6e-13 49.7 0.0 1.2e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62177.1 - 3.9e-12 46.1 0.0 1.4e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG62177.1 - 0.01 16.4 0.0 0.03 15.0 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease RVP_2 PF08284.11 GBG62177.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG62177.1 - 0.027 15.1 0.0 0.051 14.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG62177.1 - 0.048 13.4 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG62178.1 - 1e-19 70.4 0.0 2.3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62178.1 - 2.6e-19 69.4 0.0 5.5e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62178.1 - 1.8e-10 40.7 1.3 3.2e-10 39.9 0.3 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG62178.1 - 0.00011 22.5 0.6 0.00028 21.2 0.6 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG62181.1 - 5.4e-31 106.6 0.0 2.5e-16 59.5 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62181.1 - 2.5e-29 101.7 0.0 6e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62181.1 - 1.4e-28 99.9 0.1 2.4e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG62181.1 - 3.9e-12 45.9 0.0 9e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG62181.1 - 3e-08 33.6 0.5 9e-08 32.1 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG62181.1 - 3.6e-08 33.6 0.0 1.3e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG62181.1 - 0.094 13.4 0.0 0.32 11.7 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease DUF1192 PF06698.11 GBG62184.1 - 0.00092 19.2 9.5 0.0013 18.8 1.3 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1192) CENP-F_leu_zip PF10473.9 GBG62184.1 - 0.032 14.2 0.8 0.032 14.2 0.8 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2937 PF11157.8 GBG62184.1 - 0.065 12.9 0.4 0.16 11.6 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) kleA_kleC PF17383.2 GBG62184.1 - 0.38 11.1 0.2 0.38 11.1 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Golgin_A5 PF09787.9 GBG62184.1 - 1.9 7.9 16.1 0.44 10.0 2.2 2.7 2 1 0 2 2 2 0 Golgin subfamily A member 5 SHE3 PF17078.5 GBG62184.1 - 3 7.5 10.3 9 5.9 0.1 2.8 1 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 BST2 PF16716.5 GBG62184.1 - 5.7 7.6 14.3 37 5.0 4.3 3.2 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Myb_DNA-bind_4 PF13837.6 GBG62185.1 - 4.3e-11 43.0 2.9 9.3e-10 38.8 1.1 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG62185.1 - 0.00023 21.2 2.1 0.00057 19.9 2.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Transcrip_act PF04949.13 GBG62185.1 - 0.0069 16.3 0.4 0.1 12.5 0.3 2.4 2 0 0 2 2 2 1 Transcriptional activator MADF_DNA_bdg PF10545.9 GBG62185.1 - 0.055 13.8 0.2 0.21 11.9 0.2 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG62186.1 - 1e-14 54.5 0.1 9.5e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62186.1 - 4.4e-07 29.7 0.0 7.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG62186.1 - 0.028 14.1 0.1 0.71 9.5 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG62187.1 - 3.4e-31 107.3 0.0 6.5e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62187.1 - 2.2e-30 105.0 0.0 4.6e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62187.1 - 5.3e-14 52.3 0.0 8.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62187.1 - 5.8e-08 32.7 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG62187.1 - 2.4e-05 24.5 0.1 6.1e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG62188.1 - 0.00088 19.6 1.5 0.0022 18.4 1.5 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG62188.1 - 0.015 15.5 0.1 0.046 13.9 0.1 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG62188.1 - 0.017 15.4 0.4 0.037 14.3 0.4 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Com_YlbF PF06133.11 GBG62188.1 - 2.6 8.7 8.1 15 6.2 2.9 2.8 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA RVT_1 PF00078.27 GBG62189.1 - 1.1e-22 80.7 0.0 2.9e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG62189.1 - 0.011 16.0 0.1 0.011 16.0 0.1 4.0 5 0 0 5 5 5 0 Retrotransposon gag protein Chromo PF00385.24 GBG62189.1 - 0.037 14.0 0.2 0.2 11.6 0.0 2.4 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain TMF_TATA_bd PF12325.8 GBG62190.1 - 0.061 13.6 0.6 0.061 13.6 0.6 3.2 3 2 1 4 4 4 0 TATA element modulatory factor 1 TATA binding MCR_C PF04609.12 GBG62190.1 - 0.15 11.2 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C PRKG1_interact PF15898.5 GBG62190.1 - 1.8 9.5 13.3 0.23 12.4 0.8 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Mucin PF01456.17 GBG62191.1 - 0.0026 17.7 24.5 0.0041 17.1 12.5 2.3 2 0 0 2 2 2 2 Mucin-like glycoprotein Adeno_E1B_55K_N PF04623.12 GBG62191.1 - 0.4 11.4 9.3 2.5 8.9 3.0 2.7 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus TPR_6 PF13174.6 GBG62193.1 - 0.096 13.4 0.5 1.3 9.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat VIT1 PF01988.19 GBG62194.1 - 2.3e-55 187.8 4.8 2.8e-55 187.5 4.8 1.1 1 0 0 1 1 1 1 VIT family FHIPEP PF00771.20 GBG62194.1 - 0.016 13.7 0.0 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family Pkinase_Tyr PF07714.17 GBG62195.1 - 1.3e-35 122.9 0.0 3.3e-34 118.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG62195.1 - 7.1e-34 117.4 0.0 8.4e-31 107.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG62195.1 - 1e-06 27.8 0.0 1.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG62195.1 - 7e-06 26.1 0.0 1.6e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GBG62195.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 GBG62196.1 - 2e-12 47.0 0.0 2.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 GBG62196.1 - 0.023 14.6 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 UEV domain AIRS_C PF02769.22 GBG62200.1 - 7.7e-30 104.1 0.1 1e-29 103.7 0.1 1.1 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain RT_RNaseH_2 PF17919.1 GBG62201.1 - 5.6e-29 100.1 0.0 1.1e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62201.1 - 1e-26 93.2 0.0 1.7e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AIRS PF00586.24 GBG62201.1 - 6.3e-13 49.2 0.1 1.4e-12 48.1 0.1 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain RVT_1 PF00078.27 GBG62201.1 - 5.3e-12 45.7 0.1 8.9e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Radial_spoke PF04712.12 GBG62201.1 - 0.2 10.6 7.4 0.28 10.1 7.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein PAC1 PF16094.5 GBG62201.1 - 0.31 10.2 3.5 3.1 6.9 5.5 1.6 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 RNA_pol_3_Rpc31 PF11705.8 GBG62201.1 - 0.61 10.3 7.6 0.97 9.6 7.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Paf1 PF03985.13 GBG62201.1 - 3.6 6.5 9.4 5.3 5.9 9.4 1.1 1 0 0 1 1 1 0 Paf1 RVT_1 PF00078.27 GBG62202.1 - 4.2e-17 62.4 0.1 6.4e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG62202.1 - 0.043 14.5 0.0 0.1 13.3 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF4483 PF14825.6 GBG62203.1 - 3.5e-24 85.4 0.0 1e-23 83.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Retrotrans_gag PF03732.17 GBG62203.1 - 0.036 14.3 6.9 1.2 9.4 0.0 3.7 3 1 0 3 3 3 0 Retrotransposon gag protein DUF4407 PF14362.6 GBG62203.1 - 0.29 10.4 12.6 0.23 10.8 5.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 GBG62203.1 - 0.96 10.1 19.3 0.059 14.0 2.3 3.2 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 GBG62203.1 - 3.1 7.7 12.8 1.4 8.7 0.2 3.0 3 0 0 3 3 3 0 Septum formation initiator ADIP PF11559.8 GBG62203.1 - 4.4 7.4 17.5 0.44 10.6 0.6 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Chromo PF00385.24 GBG62204.1 - 0.0017 18.3 0.1 0.0029 17.5 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Keratin_2_head PF16208.5 GBG62204.1 - 0.93 9.6 22.1 1.6 8.8 22.1 1.3 1 0 0 1 1 1 0 Keratin type II head zf-CCHC PF00098.23 GBG62205.1 - 8.7e-06 25.6 4.0 1.7e-05 24.6 4.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG62205.1 - 0.14 11.9 0.7 0.3 10.8 0.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG62205.1 - 0.19 11.6 4.4 0.33 10.8 4.4 1.3 1 0 0 1 1 1 0 Zinc knuckle BT1 PF03092.16 GBG62205.1 - 6.1 4.9 5.3 8.5 4.5 5.3 1.2 1 0 0 1 1 1 0 BT1 family PsaD PF02531.16 GBG62206.1 - 8.7e-69 229.3 0.1 1.1e-68 228.9 0.1 1.1 1 0 0 1 1 1 1 PsaD DDE_Tnp_4 PF13359.6 GBG62207.1 - 1.4e-22 80.0 0.0 4.6e-22 78.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62207.1 - 1.4e-11 44.4 0.0 2.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG62207.1 - 0.0044 16.7 0.6 0.04 13.6 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG62207.1 - 0.07 13.5 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Transposase DDE domain DSHCT PF08148.12 GBG62207.1 - 0.081 12.6 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain zf-C3HC4_3 PF13920.6 GBG62211.1 - 2.8e-10 39.9 8.7 4.3e-10 39.3 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG62211.1 - 4.2e-10 39.8 13.2 7.7e-10 39.0 13.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG62211.1 - 1.1e-08 34.7 12.1 1.8e-08 34.1 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG62211.1 - 2.5e-08 33.8 8.1 5e-08 32.8 8.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG62211.1 - 3.5e-08 33.2 11.8 5.5e-08 32.5 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG62211.1 - 1.6e-06 27.9 9.0 2.6e-06 27.2 9.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GBG62211.1 - 5.1e-06 26.7 12.0 1.5e-05 25.2 12.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GBG62211.1 - 5.2e-06 26.3 10.3 8.7e-06 25.6 10.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GBG62211.1 - 5.4e-06 26.5 10.1 9.9e-06 25.6 10.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GBG62211.1 - 0.0039 17.0 4.6 0.0078 16.1 4.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 GBG62211.1 - 0.0053 16.4 8.4 0.01 15.5 8.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 GBG62211.1 - 0.016 15.5 1.3 0.033 14.4 1.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family zf-ANAPC11 PF12861.7 GBG62211.1 - 0.046 13.8 5.2 0.16 12.1 5.2 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GAGA PF09237.11 GBG62211.1 - 0.099 12.5 1.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 GAGA factor zf-Nse PF11789.8 GBG62211.1 - 0.14 12.0 4.7 0.25 11.2 4.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 GBG62211.1 - 0.23 11.6 5.9 0.43 10.7 5.9 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 GBG62211.1 - 3.7 7.4 8.7 10 6.0 8.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 GBG62211.1 - 5 7.2 6.9 12 6.0 6.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C3H2C3 PF17122.5 GBG62211.1 - 6.8 6.8 8.0 12 6.1 8.0 1.4 1 0 0 1 1 1 0 Zinc-finger Polyketide_cyc PF03364.20 GBG62213.1 - 7.9e-12 45.5 0.1 1.4e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GBG62213.1 - 0.00086 19.6 0.2 0.0027 18.0 0.1 1.8 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport TIC20 PF16166.5 GBG62215.1 - 2.5e-24 86.0 3.2 3.5e-24 85.6 3.2 1.2 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like Myc_N PF01056.18 GBG62215.1 - 0.0038 17.2 0.2 0.0057 16.6 0.2 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Borrelia_P83 PF05262.11 GBG62216.1 - 0.0046 15.5 21.8 0.0052 15.3 21.8 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein TIC20 PF16166.5 GBG62217.1 - 5.2e-34 117.6 3.0 6.9e-34 117.2 3.0 1.1 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like RVP_2 PF08284.11 GBG62218.1 - 1.5e-09 37.7 0.0 3.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62218.1 - 8e-08 32.8 0.0 3.5e-07 30.8 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62218.1 - 1.1e-06 29.1 0.0 4.6e-06 27.1 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rab5-bind PF09311.11 GBG62218.1 - 0.16 11.4 4.9 0.22 10.9 4.9 1.2 1 0 0 1 1 1 0 Rabaptin-like protein SlyX PF04102.12 GBG62218.1 - 3.5 8.3 7.6 0.29 11.8 0.7 2.7 3 0 0 3 3 3 0 SlyX FSA_C PF10479.9 GBG62220.1 - 0.05 11.7 6.9 0.071 11.2 6.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF4604 PF15377.6 GBG62220.1 - 0.076 13.4 3.7 0.14 12.6 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Mucin PF01456.17 GBG62220.1 - 0.19 11.7 23.1 0.34 10.9 23.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 GBG62220.1 - 4.9 7.6 11.4 9.8 6.6 11.4 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Med3 PF11593.8 GBG62220.1 - 9.2 5.3 17.3 16 4.5 17.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RT_RNaseH_2 PF17919.1 GBG62221.1 - 2e-26 92.0 0.0 3.1e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62221.1 - 1.9e-22 79.5 0.0 2.9e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62222.1 - 3.8e-28 97.5 0.0 6.5e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62222.1 - 9.1e-26 90.2 0.0 1.5e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62222.1 - 1.3e-14 54.3 0.0 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG62222.1 - 0.23 9.6 19.3 0.32 9.1 19.3 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG62222.1 - 1.8 8.3 15.1 2.8 7.6 15.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RCC1 PF00415.18 GBG62223.1 - 1.2e-55 185.9 33.3 1.9e-11 44.4 0.4 10.7 11 0 0 11 11 11 9 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG62223.1 - 8.3e-25 86.0 50.0 3.9e-09 36.1 1.0 9.2 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat Nop14 PF04147.12 GBG62224.1 - 0.058 11.6 5.6 0.076 11.2 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG62224.1 - 0.61 8.3 6.4 0.84 7.9 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG62224.1 - 1 8.7 10.5 2 7.7 10.5 1.4 1 0 0 1 1 1 0 SDA1 LANC_like PF05147.13 GBG62225.1 - 1.4e-82 277.1 0.0 1.6e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_127 PF07944.12 GBG62225.1 - 0.068 11.7 0.0 0.17 10.4 0.0 1.5 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 NPL PF17800.1 GBG62226.1 - 4.9e-13 49.6 0.0 4.9e-13 49.6 0.0 2.9 2 1 0 2 2 2 1 Nucleoplasmin-like domain zf-C2H2_6 PF13912.6 GBG62226.1 - 6.2e-05 22.9 1.3 0.00011 22.1 1.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 GBG62226.1 - 8.4e-05 22.8 0.8 0.00014 22.1 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GBG62226.1 - 0.00016 21.8 0.2 0.00031 20.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GBG62226.1 - 0.0019 18.9 0.5 0.0035 18.1 0.5 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 GBG62226.1 - 0.0048 17.3 0.4 0.008 16.6 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type MCM_bind PF09739.9 GBG62228.1 - 1.2e-137 459.9 0.0 5.8e-135 451.0 0.0 2.0 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor gag-asp_proteas PF13975.6 GBG62229.1 - 8e-08 32.7 0.1 3e-07 30.9 0.1 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62229.1 - 1.6e-06 28.7 0.1 8.1e-06 26.4 0.1 2.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62229.1 - 1.5e-05 24.8 0.1 3.1e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG62229.1 - 0.0038 17.0 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG62229.1 - 0.17 11.6 0.2 0.34 10.6 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG62229.1 - 0.47 10.6 1.9 0.89 9.7 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle UQ_con PF00179.26 GBG62231.1 - 3.3e-52 175.9 0.0 3.7e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GBG62231.1 - 0.016 15.5 0.0 0.017 15.4 0.0 1.4 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 GBG62231.1 - 0.025 14.3 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B Flagellin_C PF00700.21 GBG62232.1 - 0.13 12.6 0.1 0.57 10.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Auxin_canalis PF05703.11 GBG62233.1 - 6.3e-55 186.9 22.9 6.3e-55 186.9 22.9 2.2 2 1 0 2 2 2 1 Auxin canalisation PH_2 PF08458.10 GBG62233.1 - 3.5e-26 91.6 0.0 6.1e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Plant pleckstrin homology-like region Auxin_canalis PF05703.11 GBG62234.1 - 1.8e-60 205.0 7.9 1.8e-60 205.0 7.9 1.7 2 0 0 2 2 2 1 Auxin canalisation PH_2 PF08458.10 GBG62234.1 - 3.2e-26 91.7 0.0 5.7e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PP2C PF00481.21 GBG62235.1 - 3.6e-52 177.5 0.0 4.7e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GBG62235.1 - 7.8e-05 22.4 0.1 0.00025 20.8 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PLD_C PF12357.8 GBG62236.1 - 1e-25 89.4 0.1 2.2e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.22 GBG62236.1 - 2.2e-16 59.3 5.3 1.2e-07 31.7 0.6 3.3 3 0 0 3 3 3 2 Phospholipase D Active site motif C2 PF00168.30 GBG62236.1 - 3.4e-11 43.4 0.0 1.4e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 C2 domain PLDc_2 PF13091.6 GBG62236.1 - 1.1e-10 41.5 0.1 1.9e-06 27.8 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain N6_N4_Mtase PF01555.18 GBG62237.1 - 3.7e-14 53.0 0.0 1.7e-05 24.7 0.0 3.6 3 1 0 3 3 3 2 DNA methylase CDC45 PF02724.14 GBG62237.1 - 5.7e-05 21.6 15.7 5.7e-05 21.6 15.7 2.9 3 0 0 3 3 3 1 CDC45-like protein SDA1 PF05285.12 GBG62237.1 - 0.00021 20.8 28.3 0.00021 20.8 28.3 3.3 3 0 0 3 3 3 1 SDA1 Nop14 PF04147.12 GBG62237.1 - 0.00089 17.6 30.2 0.00089 17.6 30.2 2.8 3 0 0 3 3 3 1 Nop14-like family RVP PF00077.20 GBG62238.1 - 0.00067 19.9 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG62238.1 - 0.0011 19.5 0.0 0.0027 18.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62238.1 - 0.0049 17.5 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62238.1 - 0.039 13.7 0.1 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG62238.1 - 0.053 13.8 0.1 0.35 11.2 0.0 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein Nop14 PF04147.12 GBG62239.1 - 0.23 9.6 17.4 0.29 9.3 17.4 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG62239.1 - 0.27 11.0 15.8 0.36 10.5 15.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG62239.1 - 0.3 10.5 16.6 0.36 10.2 16.6 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG62239.1 - 0.63 9.3 16.1 0.77 9.0 16.1 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG62239.1 - 1.4 7.1 14.2 1.7 6.8 14.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG62240.1 - 5.1e-22 78.4 0.0 7.3e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PLD_C PF12357.8 GBG62241.1 - 9.2e-25 86.4 0.1 1.7e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.22 GBG62241.1 - 1.2e-16 60.1 4.0 1.5e-07 31.3 0.6 3.2 3 0 0 3 3 3 2 Phospholipase D Active site motif C2 PF00168.30 GBG62241.1 - 4.7e-12 46.1 0.0 3.9e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 C2 domain PLDc_2 PF13091.6 GBG62241.1 - 2.7e-10 40.2 0.5 1.2e-06 28.4 0.2 3.2 2 1 0 2 2 2 2 PLD-like domain BUD22 PF09073.10 GBG62242.1 - 0.0062 15.9 13.6 0.0087 15.4 13.6 1.2 1 0 0 1 1 1 1 BUD22 GCIP PF13324.6 GBG62242.1 - 0.7 9.4 4.7 1 8.9 4.7 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting 2OG-FeII_Oxy_2 PF13532.6 GBG62244.1 - 2.1e-11 44.4 0.0 5.8e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PEN-2 PF10251.9 GBG62245.1 - 2e-17 63.4 0.5 2.7e-17 62.9 0.5 1.2 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase M16C_assoc PF08367.11 GBG62246.1 - 3.8e-59 199.9 0.0 5.3e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 GBG62246.1 - 2.2e-20 73.5 0.2 1.6e-19 70.7 0.0 2.5 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GBG62246.1 - 7.6e-07 29.2 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PAP_PilO PF06864.12 GBG62247.1 - 0.061 12.1 0.1 0.08 11.8 0.1 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) zf-CCCH_2 PF14608.6 GBG62249.1 - 5.5e-11 42.5 44.5 0.013 15.9 0.5 6.4 6 0 0 6 6 6 6 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 GBG62249.1 - 4.8e-09 35.9 41.9 0.0038 17.1 0.5 7.0 6 1 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 GBG62249.1 - 3.3e-08 33.7 20.6 0.00027 21.1 2.2 3.6 3 1 0 3 3 3 3 Zinc-finger containing family zf-CCCH_4 PF18044.1 GBG62249.1 - 4.4e-07 29.5 61.2 9.7e-05 22.1 1.0 7.8 6 3 0 6 6 6 3 CCCH-type zinc finger Torus PF16131.5 GBG62249.1 - 1.7e-05 25.5 36.2 0.11 13.2 0.3 6.1 3 3 3 6 6 6 4 Torus domain zf_CCCH_4 PF18345.1 GBG62249.1 - 7.3e-05 22.7 1.1 7.3e-05 22.7 1.1 8.0 7 3 0 7 7 7 3 Zinc finger domain Gliadin PF13016.6 GBG62249.1 - 0.057 13.8 4.5 57 4.2 0.0 4.6 3 2 2 5 5 5 0 Cys-rich Gliadin N-terminal CDC45 PF02724.14 GBG62249.1 - 0.11 10.7 14.5 0.16 10.2 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG62249.1 - 0.19 9.9 12.9 0.25 9.5 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family Prothymosin PF03247.14 GBG62249.1 - 0.45 11.0 25.2 0.74 10.3 25.2 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family MDM1 PF15501.6 GBG62249.1 - 1.1 8.3 14.0 1.5 7.9 14.0 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 SDA1 PF05285.12 GBG62249.1 - 3.2 7.1 17.2 4.5 6.6 17.2 1.1 1 0 0 1 1 1 0 SDA1 eIF3_subunit PF08597.10 GBG62249.1 - 5.7 6.8 16.6 9.4 6.1 16.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Apt1 PF10351.9 GBG62249.1 - 6.1 5.6 6.2 8.5 5.1 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Paf1 PF03985.13 GBG62249.1 - 6.6 5.6 17.7 9.3 5.1 17.7 1.1 1 0 0 1 1 1 0 Paf1 SBP_bac_5 PF00496.22 GBG62250.1 - 0.043 12.8 0.0 0.043 12.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle SspO PF08175.12 GBG62250.1 - 0.098 13.1 1.9 0.15 12.6 0.7 1.8 1 1 1 2 2 2 0 Small acid-soluble spore protein O family DUF659 PF04937.15 GBG62252.1 - 7.7e-30 103.8 0.0 1.5e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG62253.1 - 1.3e-25 89.3 0.0 3.1e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62253.1 - 4.4e-22 78.4 0.0 9.4e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62253.1 - 0.0063 16.0 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyl-CoA_dh_C PF12806.7 GBG62253.1 - 0.077 13.2 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like DIE2_ALG10 PF04922.12 GBG62254.1 - 1.3e-72 245.3 1.1 3.2e-68 230.8 0.2 2.5 2 0 0 2 2 2 2 DIE2/ALG10 family RVT_1 PF00078.27 GBG62254.1 - 2e-24 86.4 0.1 3.5e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chorion_2 PF03964.15 GBG62254.1 - 3.3 8.6 9.5 7.7 7.4 8.9 1.9 1 1 0 1 1 1 0 Chorion family 2 DUF1666 PF07891.12 GBG62255.1 - 0.12 12.0 5.3 0.16 11.6 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) DUF45 PF01863.17 GBG62255.1 - 0.26 11.3 2.4 0.39 10.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF5446 PF17522.2 GBG62255.1 - 9.6 6.5 9.6 0.44 10.7 2.7 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5446) PTEN_C2 PF10409.9 GBG62257.1 - 3.5e-10 39.7 0.0 6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase3 PF13350.6 GBG62257.1 - 7.9e-07 29.3 0.0 9.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GBG62257.1 - 3.1e-06 27.1 0.0 6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GBG62257.1 - 0.00099 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GBG62257.1 - 0.0035 17.5 0.0 0.0069 16.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DDE_Tnp_4 PF13359.6 GBG62258.1 - 1.8e-29 102.5 0.0 3.2e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62258.1 - 3.6e-13 49.6 0.0 7.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG62258.1 - 0.014 15.1 0.1 1.6 8.3 0.3 2.5 2 0 0 2 2 2 0 Transposase DDE domain RT_RNaseH PF17917.1 GBG62260.1 - 4.8e-24 84.7 0.0 7.4e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62260.1 - 2.5e-23 82.0 0.0 3.7e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62260.1 - 1.4e-18 66.7 0.0 2.9e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG62260.1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Dimer_Tnp_hAT PF05699.14 GBG62261.1 - 5.4e-07 29.3 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pro_Al_protease PF02983.14 GBG62261.1 - 0.1 12.6 0.1 0.33 11.0 0.1 1.8 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Myb_DNA-bind_4 PF13837.6 GBG62262.1 - 7.1e-09 35.9 0.6 1.7e-08 34.8 0.6 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG62262.1 - 0.059 13.7 0.2 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG62263.1 - 1.3e-31 109.4 0.0 3.8e-31 107.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62263.1 - 1.5e-11 44.3 0.0 2.5e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG62263.1 - 0.043 13.5 0.2 9.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain Beach PF02138.18 GBG62263.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Beige/BEACH domain Histone PF00125.24 GBG62264.1 - 2.5e-23 82.9 0.3 5.3e-23 81.8 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 UQ_con PF00179.26 GBG62265.1 - 1.2e-38 131.9 0.0 1.3e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GBG62265.1 - 0.0029 17.9 0.0 0.0029 17.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 GBG62265.1 - 0.046 13.4 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 GBG62265.1 - 0.12 12.2 0.3 0.21 11.5 0.1 1.5 2 0 0 2 2 2 0 UEV domain NOGCT PF08155.11 GBG62266.1 - 0.012 15.5 1.8 4.2 7.4 0.0 2.8 2 0 0 2 2 2 0 NOGCT (NUC087) domain PspA_IM30 PF04012.12 GBG62267.1 - 6.2e-26 91.4 12.2 6.2e-26 91.4 12.2 3.0 4 0 0 4 4 4 1 PspA/IM30 family RIX1 PF08167.12 GBG62267.1 - 1.5e-25 90.1 0.1 2.7e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis HEAT PF02985.22 GBG62267.1 - 0.062 13.6 0.3 0.22 11.9 0.3 2.1 1 0 0 1 1 1 0 HEAT repeat MS_channel PF00924.18 GBG62268.1 - 1.3e-30 106.5 0.5 1.7e-30 106.1 0.5 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel LRR_4 PF12799.7 GBG62269.1 - 6.6e-09 35.9 4.7 9e-05 22.8 0.1 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG62269.1 - 1.6e-07 31.0 6.0 0.00021 21.0 0.9 2.7 2 1 1 3 3 3 2 Leucine rich repeat Chloroa_b-bind PF00504.21 GBG62269.1 - 0.0002 22.0 0.1 0.00057 20.5 0.0 1.8 2 0 0 2 2 2 1 Chlorophyll A-B binding protein LRR_6 PF13516.6 GBG62269.1 - 0.077 13.1 11.4 9.1 6.6 0.2 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 GBG62269.1 - 0.19 12.4 5.7 6.2 7.8 0.3 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat CDC45 PF02724.14 GBG62269.1 - 0.46 8.7 20.8 0.6 8.3 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein LRR_8 PF13855.6 GBG62270.1 - 1.4e-40 136.8 29.1 1.7e-11 43.7 7.4 6.2 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GBG62270.1 - 6.4e-32 109.1 27.3 4.1e-05 23.8 2.5 7.9 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 GBG62270.1 - 1.3e-09 38.1 0.0 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 GBG62270.1 - 3.1e-08 33.3 5.3 0.0069 15.9 0.3 4.0 2 2 1 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 GBG62270.1 - 8.2e-08 31.8 31.6 5.9 7.8 0.3 12.4 12 2 0 12 12 12 3 Leucine Rich Repeat LRR_6 PF13516.6 GBG62270.1 - 0.00055 19.8 35.2 4.5 7.6 0.2 11.1 12 0 0 12 12 12 2 Leucine Rich repeat LRR_3 PF07725.12 GBG62270.1 - 0.028 14.3 0.9 4.8 7.2 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat HemN_C PF06969.16 GBG62270.1 - 0.033 14.3 0.9 50 4.1 0.0 4.0 3 1 1 4 4 4 0 HemN C-terminal domain CENP-H PF05837.12 GBG62271.1 - 0.019 15.3 0.5 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) RVT_1 PF00078.27 GBG62272.1 - 1.3e-34 119.7 0.1 2e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG62272.1 - 4.5e-10 39.8 0.0 1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain eIF-1a PF01176.19 GBG62272.1 - 0.002 17.9 0.1 0.0045 16.8 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CCD48 PF15799.5 GBG62272.1 - 0.0022 16.4 3.1 0.0035 15.7 3.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 rve_3 PF13683.6 GBG62272.1 - 0.022 14.5 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain DUF2385 PF09539.10 GBG62272.1 - 0.16 12.5 0.1 2.8 8.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) HALZ PF02183.18 GBG62272.1 - 0.4 10.9 4.5 0.18 12.1 1.2 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 GBG62272.1 - 4.1 7.6 8.8 3.3 7.9 2.5 2.7 2 0 0 2 2 2 0 Basic region leucine zipper zf-CCHC PF00098.23 GBG62273.1 - 0.11 12.6 3.9 0.19 11.9 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle CTNNB1_binding PF08347.11 GBG62273.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.8 3 0 0 3 3 3 0 N-terminal CTNNB1 binding Phage_holin_7_1 PF16081.5 GBG62273.1 - 0.19 11.9 0.9 0.61 10.3 0.1 2.1 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Shugoshin_N PF07558.11 GBG62273.1 - 0.22 11.4 5.3 1.1 9.2 0.1 3.6 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region UPF0767 PF15990.5 GBG62273.1 - 6.8 6.9 7.6 5 7.3 0.1 3.0 2 0 0 2 2 2 0 UPF0767 family TIM21 PF08294.11 GBG62274.1 - 1.9e-05 24.6 0.0 7.3e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 TIM21 Coa1 PF08695.10 GBG62274.1 - 0.0004 20.1 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 GOLD_2 PF13897.6 GBG62274.1 - 0.25 11.8 0.6 0.44 11.0 0.6 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Integrase_H2C2 PF17921.1 GBG62275.1 - 4.5e-13 49.1 0.0 8.6e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62275.1 - 1.1e-12 48.2 0.0 2.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG62275.1 - 1.8e-06 28.4 0.0 4.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62275.1 - 3e-05 24.6 0.0 8.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG62275.1 - 0.0066 16.7 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 GBG62275.1 - 0.025 14.3 0.3 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 GBG62275.1 - 0.15 12.3 0.3 0.34 11.2 0.3 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Glyco_hydro_17 PF00332.18 GBG62277.1 - 1e-50 173.1 0.1 1.4e-50 172.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Methyltransf_29 PF03141.16 GBG62278.1 - 1e-207 690.7 0.0 1.2e-207 690.5 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 GBG62278.1 - 4.7e-08 33.6 0.0 2.9e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GBG62278.1 - 1.4e-06 28.9 0.0 0.00028 21.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG62278.1 - 0.0001 22.1 0.0 0.19 11.5 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain DUF3306 PF11748.8 GBG62279.1 - 5 8.0 11.4 7.4 7.5 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Methyltransf_29 PF03141.16 GBG62280.1 - 2.1e-152 508.2 0.0 2.7e-152 507.9 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 GBG62280.1 - 2.2e-07 31.4 0.0 0.00024 21.7 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GBG62280.1 - 2.4e-05 24.2 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GBG62280.1 - 8.6e-05 23.2 0.0 0.029 15.1 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG62280.1 - 0.00018 21.4 0.0 0.19 11.6 0.1 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_29 PF03141.16 GBG62282.1 - 1.5e-208 693.5 0.0 1.7e-208 693.3 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 GBG62282.1 - 3.8e-08 33.9 0.0 2.6e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GBG62282.1 - 1.2e-06 29.1 0.0 0.00025 21.7 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG62282.1 - 2.9e-05 23.9 0.0 0.14 11.9 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain RVT_1 PF00078.27 GBG62283.1 - 8.3e-25 87.6 0.1 1.3e-24 87.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62283.1 - 1.5e-17 63.4 0.1 3.9e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62283.1 - 7.3e-06 26.2 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG62283.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG62283.1 - 0.15 12.3 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase HECT PF00632.25 GBG62284.1 - 6.3e-91 305.1 0.0 1e-90 304.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AA_kinase PF00696.28 GBG62285.1 - 3.8e-42 144.5 0.5 5.2e-42 144.1 0.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PhaC_N PF07167.13 GBG62285.1 - 0.26 10.9 0.0 0.63 9.7 0.0 1.6 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Myb_DNA-bind_4 PF13837.6 GBG62286.1 - 3.8e-10 40.0 0.4 7.6e-10 39.0 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain UPF0240 PF06784.11 GBG62286.1 - 0.027 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) DUF2207 PF09972.9 GBG62287.1 - 1.4 7.6 12.5 1.7 7.3 12.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4637 PF15470.6 GBG62287.1 - 4.1 7.1 6.9 6.1 6.5 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Utp13 PF08625.11 GBG62288.1 - 1.4e-40 138.5 0.0 3.3e-40 137.3 0.0 1.7 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain WD40 PF00400.32 GBG62288.1 - 4.3e-33 112.8 33.7 3.4e-07 30.8 0.2 10.6 11 1 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG62288.1 - 1.9e-11 44.1 4.8 0.011 16.0 0.0 6.2 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG62288.1 - 6.5e-08 31.7 9.1 0.0034 16.1 0.1 6.1 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GBG62288.1 - 0.00092 18.3 5.4 1.4 7.8 0.1 5.0 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GBG62288.1 - 0.0014 17.5 0.1 0.098 11.4 0.0 3.0 3 0 0 3 3 3 1 Nup133 N terminal like SWI-SNF_Ssr4 PF08549.10 GBG62288.1 - 1.3 7.6 10.1 2 6.9 10.1 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Ferlin_C PF16165.5 GBG62288.1 - 2.3 8.1 4.7 2.8 7.9 1.4 2.4 2 0 0 2 2 2 0 Ferlin C-terminus SEEEED PF14797.6 GBG62288.1 - 2.5 8.3 11.8 8.1 6.6 11.8 1.8 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex RR_TM4-6 PF06459.12 GBG62288.1 - 5.1 6.8 9.9 12 5.7 9.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Myb_DNA-bind_4 PF13837.6 GBG62291.1 - 1.4e-34 118.3 10.7 5.6e-20 71.5 1.0 2.8 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG62291.1 - 1.7e-08 34.7 15.9 8.4e-05 22.8 0.2 3.3 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG62291.1 - 3e-05 24.1 2.6 0.096 12.9 0.2 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG62291.1 - 3.1e-05 24.1 4.7 0.036 14.3 0.5 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG62291.1 - 4.3e-05 23.5 6.6 0.041 14.0 0.3 3.1 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain LegC3_N PF18654.1 GBG62291.1 - 0.049 12.9 21.4 0.12 11.6 7.6 2.3 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain Vps39_2 PF10367.9 GBG62291.1 - 2.8 8.4 9.7 0.37 11.2 1.3 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 AAA_23 PF13476.6 GBG62291.1 - 5.1 7.5 11.7 14 6.1 0.3 2.5 2 0 0 2 2 2 0 AAA domain DNA_ligase_A_M PF01068.21 GBG62293.1 - 3.7e-41 141.0 0.0 9.9e-22 77.6 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GBG62293.1 - 2.9e-38 131.9 0.0 5.1e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DRMBL PF07522.14 GBG62293.1 - 1.6e-19 70.1 0.0 3.3e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase DNA_ligase_A_C PF04679.15 GBG62293.1 - 5.7e-19 68.6 0.0 1.6e-18 67.1 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RMMBL PF07521.12 GBG62293.1 - 0.0013 18.6 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain UPF0029 PF01205.19 GBG62294.1 - 4.8e-35 120.1 0.0 3.1e-34 117.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 GBG62294.1 - 7e-16 58.5 0.0 1.4e-15 57.6 0.0 1.5 1 1 0 1 1 1 1 RWD domain Gon7 PF08738.10 GBG62296.1 - 0.16 12.0 6.3 2.5 8.2 5.2 2.7 2 0 0 2 2 2 0 Gon7 family RVT_1 PF00078.27 GBG62297.1 - 1.7e-30 106.2 0.1 2.3e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG62298.1 - 0.41 10.8 3.0 0.8 9.9 3.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Hen1_Lam_C PF18441.1 GBG62300.1 - 1.9e-24 86.1 0.0 5.6e-15 55.4 0.0 2.7 2 1 0 2 2 2 2 Hen1 La-motif C-terminal domain dsRBD2 PF17842.1 GBG62300.1 - 4.3e-14 52.9 14.6 3.1e-13 50.1 0.1 4.0 4 0 0 4 4 4 2 Double-stranded RNA binding domain 2 Methyltransf_31 PF13847.6 GBG62300.1 - 5.5e-05 23.0 0.0 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FKBP_C PF00254.28 GBG62300.1 - 6.7e-05 23.1 0.0 0.0019 18.5 0.0 2.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Methyltransf_12 PF08242.12 GBG62300.1 - 0.0001 23.0 0.0 0.00029 21.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG62300.1 - 0.00025 21.7 0.0 0.0008 20.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG62300.1 - 0.003 18.2 0.0 0.0088 16.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Dicer_dimer PF03368.14 GBG62300.1 - 0.0051 16.9 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain MTS PF05175.14 GBG62300.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RabGAP-TBC PF00566.18 GBG62301.1 - 7.4e-55 185.9 0.1 2e-54 184.5 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain BRCT_2 PF16589.5 GBG62302.1 - 0.02 15.3 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GBG62302.1 - 0.023 15.1 0.0 0.057 13.8 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF3499 PF12005.8 GBG62302.1 - 2.7 8.6 7.8 8 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) BRCT_2 PF16589.5 GBG62303.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GBG62303.1 - 0.015 15.7 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain zf-CCHC PF00098.23 GBG62304.1 - 0.024 14.7 1.5 0.042 13.9 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle BRCT_2 PF16589.5 GBG62305.1 - 0.00016 22.0 0.0 0.00029 21.2 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 GBG62307.1 - 8.2e-18 65.2 0.0 2.6e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 GBG62307.1 - 1.2e-12 48.1 0.0 6.1e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family IMS_HHH PF11798.8 GBG62307.1 - 4.6e-06 26.6 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Retrotrans_gag PF03732.17 GBG62307.1 - 0.0059 16.8 0.1 0.0059 16.8 0.1 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG62307.1 - 0.19 11.5 3.8 0.14 11.9 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG62307.1 - 0.21 10.9 8.6 0.72 9.2 8.6 1.9 1 0 0 1 1 1 0 FAM76 protein Pheromone PF08015.11 GBG62307.1 - 0.93 10.6 3.1 14 6.8 0.0 3.5 3 0 0 3 3 3 0 Fungal mating-type pheromone IMS_C PF11799.8 GBG62309.1 - 7e-18 65.4 0.0 1.6e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Integrase_H2C2 PF17921.1 GBG62310.1 - 1.3e-19 70.0 0.4 2.8e-19 69.0 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG62310.1 - 0.00033 20.8 0.1 0.00068 19.8 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger ADP_ribosyl_GH PF03747.14 GBG62310.1 - 6.6 6.4 7.5 0.5 10.0 0.7 2.4 2 1 0 2 2 2 0 ADP-ribosylglycohydrolase Nsp1_C PF05064.13 GBG62311.1 - 0.032 14.0 0.1 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region DivIC PF04977.15 GBG62311.1 - 0.76 9.6 5.6 0.16 11.8 1.2 2.0 2 0 0 2 2 2 0 Septum formation initiator UBM PF14377.6 GBG62312.1 - 0.005 16.3 0.2 12 5.5 0.3 4.3 4 0 0 4 4 4 1 Ubiquitin binding region DUF3926 PF13080.6 GBG62312.1 - 0.0089 15.9 0.4 21 5.1 0.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3926) FliG_M PF14841.6 GBG62312.1 - 0.19 12.0 0.1 1.3e+02 2.9 0.0 3.5 4 0 0 4 4 4 0 FliG middle domain zf-CCHC PF00098.23 GBG62312.1 - 0.19 11.9 0.4 0.38 10.9 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Acetate_kinase PF00871.17 GBG62315.1 - 1.1e-135 452.3 0.0 1.3e-135 452.1 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Response_reg PF00072.24 GBG62316.1 - 5.9e-26 90.8 0.1 3.7e-22 78.6 0.2 3.2 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 GBG62317.1 - 2e-17 63.0 0.0 5.6e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ARL6IP6 PF15062.6 GBG62317.1 - 0.27 11.4 0.0 0.27 11.4 0.0 2.4 3 0 0 3 3 3 0 Haemopoietic lineage transmembrane helix RCDG1 PF15725.5 GBG62317.1 - 0.45 11.0 4.5 1.3 9.5 4.5 1.7 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Trypan_PARP PF05887.11 GBG62317.1 - 2.2 8.3 11.4 1.2 9.1 0.3 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Retrotrans_gag PF03732.17 GBG62319.1 - 0.0017 18.6 0.1 0.0017 18.6 0.1 2.8 3 1 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG62319.1 - 0.0076 16.0 0.8 0.021 14.6 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Sigma54_AID PF00309.20 GBG62319.1 - 2.3 8.2 5.3 4.9 7.1 5.3 1.6 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) TFIIA PF03153.13 GBG62319.1 - 4.2 7.3 13.4 1.2 9.1 9.1 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TetR_C_2 PF08361.11 GBG62320.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Fasciclin PF02469.22 GBG62320.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Fasciclin domain RT_RNaseH_2 PF17919.1 GBG62321.1 - 2.8e-27 94.7 0.0 4.9e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62321.1 - 1.8e-25 89.2 0.0 3.5e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62321.1 - 1.6e-09 37.6 0.1 2.5e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG62321.1 - 0.36 9.0 6.3 0.45 8.7 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG62321.1 - 7.6 4.7 8.9 10 4.3 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG62323.1 - 2e-27 95.2 0.0 6.7e-27 93.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62323.1 - 1.1e-24 86.8 0.0 3.3e-24 85.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62323.1 - 1.2e-17 64.2 0.0 3.3e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG62323.1 - 0.00087 19.5 0.0 0.0034 17.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG62323.1 - 0.0044 17.6 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62323.1 - 0.011 16.3 0.0 0.037 14.6 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease TRPM_tetra PF16519.5 GBG62323.1 - 0.036 14.2 1.8 1.6 8.9 0.4 4.0 4 0 0 4 4 4 0 Tetramerisation domain of TRPM DUF2730 PF10805.8 GBG62323.1 - 0.037 14.1 2.5 0.29 11.2 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 GBG62323.1 - 0.043 13.8 2.1 15 5.7 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Chromo PF00385.24 GBG62323.1 - 0.082 12.8 0.0 0.27 11.2 0.0 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG62323.1 - 0.18 11.6 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Baculo_PEP_C PF04513.12 GBG62323.1 - 2.4 8.2 13.0 2.9 7.9 1.8 2.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DLH PF01738.18 GBG62324.1 - 2.1e-21 76.5 0.0 2.7e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GBG62324.1 - 8.9e-07 28.4 0.0 0.002 17.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 GBG62324.1 - 0.061 13.2 0.1 0.46 10.4 0.0 2.0 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 GBG62324.1 - 0.12 10.9 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II FSH1 PF03959.13 GBG62324.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) F420H2_quin_red PF04075.14 GBG62325.1 - 0.092 12.9 0.2 16 5.6 0.0 2.4 2 0 0 2 2 2 0 F420H(2)-dependent quinone reductase F420H2_quin_red PF04075.14 GBG62326.1 - 0.059 13.5 0.2 13 5.9 0.0 2.4 2 0 0 2 2 2 0 F420H(2)-dependent quinone reductase UQ_con PF00179.26 GBG62328.1 - 2.1e-16 59.8 0.1 3.4e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GBG62328.1 - 0.088 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.26 GBG62329.1 - 2.9e-16 59.4 0.1 4.6e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme APC_basic PF05956.11 GBG62329.1 - 0.013 14.9 1.8 0.017 14.6 1.8 1.2 1 0 0 1 1 1 0 APC basic domain RWD PF05773.22 GBG62329.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain Ribosomal_L15e PF00827.17 GBG62330.1 - 1.8e-73 246.3 1.6 4.3e-73 245.1 1.6 1.5 1 1 0 1 1 1 1 Ribosomal L15 UBA_6 PF18039.1 GBG62330.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain Ribosomal_L16 PF00252.18 GBG62331.1 - 8.3e-42 142.3 0.1 1.1e-41 141.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DFRP_C PF16543.5 GBG62331.1 - 0.0023 18.4 1.0 0.027 14.9 0.4 2.2 2 0 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 Integrase_H2C2 PF17921.1 GBG62332.1 - 8.9e-14 51.4 0.1 2.5e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62332.1 - 1.4e-06 28.5 0.0 2.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG62332.1 - 3.9e-06 27.3 0.0 8.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62332.1 - 9.5e-05 23.0 0.0 0.00024 21.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62332.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG62332.1 - 0.084 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG62333.1 - 0.00025 21.2 0.3 0.00049 20.3 0.1 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG62333.1 - 0.0014 18.3 0.6 0.0037 17.0 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RVT_1 PF00078.27 GBG62334.1 - 9.8e-07 28.5 0.0 3.8e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG62335.1 - 9.3e-15 54.7 0.1 1.2e-14 54.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG62335.1 - 3 7.1 23.4 4.1 6.7 23.4 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG62335.1 - 3.4 7.0 20.7 4.1 6.7 20.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG62335.1 - 4.2 5.5 15.5 5.4 5.2 15.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG62335.1 - 6.6 6.2 14.8 9.1 5.7 14.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-CCHC PF00098.23 GBG62336.1 - 0.00035 20.5 3.4 0.00064 19.7 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle T2SS-T3SS_pil_N PF13629.6 GBG62337.1 - 0.17 11.7 0.4 26 4.6 0.0 2.8 2 1 0 2 2 2 0 Pilus formation protein N terminal region Folliculin PF11704.8 GBG62337.1 - 2.3 8.1 8.5 6.7 6.5 8.5 1.8 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport CDC45 PF02724.14 GBG62337.1 - 4.2 5.5 14.3 6.7 4.9 14.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1682 PF07946.14 GBG62337.1 - 5.8 6.0 18.9 12 5.0 18.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PBP_sp32 PF07222.12 GBG62337.1 - 7.7 5.9 11.1 16 4.9 11.1 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RT_RNaseH_2 PF17919.1 GBG62338.1 - 7e-26 90.2 0.0 1.2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62338.1 - 7.1e-25 87.3 0.0 1.2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62338.1 - 1.1e-13 51.2 0.1 1.6e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG62338.1 - 0.0047 16.8 0.0 0.21 11.5 0.1 2.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2249) Mpp10 PF04006.12 GBG62338.1 - 0.28 9.6 24.9 0.38 9.1 24.9 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF659 PF04937.15 GBG62340.1 - 6.1e-18 65.1 0.0 1.4e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG62340.1 - 1.3e-05 24.9 0.6 8e-05 22.4 0.6 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG62340.1 - 0.0011 18.5 14.5 0.086 12.8 3.9 2.7 2 0 0 2 2 2 2 AT hook motif RVT_1 PF00078.27 GBG62341.1 - 4.3e-35 121.2 0.0 6.4e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62341.1 - 1.8e-19 69.6 0.0 6.4e-19 67.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62341.1 - 2.1e-08 34.4 0.0 4.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG62341.1 - 1.8e-06 27.8 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62341.1 - 1.1e-05 26.0 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62341.1 - 0.0013 19.2 0.1 0.0047 17.5 0.1 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4392 PF14336.6 GBG62341.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF1758 PF05585.12 GBG62341.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG62341.1 - 0.041 13.7 0.1 0.18 11.6 0.1 2.0 1 1 0 1 1 1 0 Aspartyl protease rve PF00665.26 GBG62342.1 - 2.9e-06 27.5 0.0 7.9e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HSP20 PF00011.21 GBG62342.1 - 1.5e-05 25.1 0.0 0.076 13.2 0.0 3.0 2 0 0 2 2 2 2 Hsp20/alpha crystallin family RVT_1 PF00078.27 GBG62342.1 - 0.0022 17.6 0.1 0.0041 16.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG62342.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Myc_N PF01056.18 GBG62342.1 - 2 8.3 8.9 1.2 9.0 0.7 3.0 3 0 0 3 3 3 0 Myc amino-terminal region SUIM_assoc PF16619.5 GBG62342.1 - 3.6 7.7 13.5 0.62 10.2 0.8 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 HSP20 PF00011.21 GBG62343.1 - 2.5e-12 46.8 0.0 1.7e-11 44.1 0.0 2.4 1 1 1 2 2 2 1 Hsp20/alpha crystallin family ORC_WH_C PF18137.1 GBG62343.1 - 0.082 13.0 0.5 0.17 12.0 0.5 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal ArsA_HSP20 PF17886.1 GBG62343.1 - 0.092 12.3 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 HSP20-like domain found in ArsA DUF4407 PF14362.6 GBG62344.1 - 0.0022 17.4 10.9 0.0028 17.0 10.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Thymidylate_kin PF02223.17 GBG62345.1 - 1.3e-46 158.6 0.0 1.6e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 GBG62345.1 - 0.056 13.7 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GBG62345.1 - 0.13 12.5 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain HSP20 PF00011.21 GBG62346.1 - 7.9e-16 58.1 0.0 1.6e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family VMA21 PF09446.10 GBG62347.1 - 1.2e-12 47.7 5.3 1.6e-12 47.3 5.3 1.2 1 0 0 1 1 1 1 VMA21-like domain Trypan_PARP PF05887.11 GBG62347.1 - 0.12 12.3 10.2 0.23 11.4 10.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 GBG62347.1 - 2.5 7.6 17.3 5.7 6.5 17.3 1.6 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Fur_reg_FbpB PF13040.6 GBG62347.1 - 6.7 6.4 7.2 9.9e+02 -0.6 7.2 3.0 1 1 0 1 1 1 0 Fur-regulated basic protein B DUF4089 PF13318.6 GBG62348.1 - 0.023 15.1 2.8 0.042 14.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4089) DUF4484 PF14831.6 GBG62348.1 - 0.033 14.2 8.6 0.043 13.9 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Cyt_bd_oxida_II PF02322.15 GBG62349.1 - 0.043 13.2 13.9 0.058 12.7 13.9 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II SLC12 PF03522.15 GBG62349.1 - 0.56 9.2 3.7 0.72 8.8 3.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 GBG62349.1 - 2.6 6.7 10.1 3.5 6.3 10.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Menin PF05053.13 GBG62349.1 - 3.8 5.8 12.2 5.5 5.2 12.2 1.3 1 0 0 1 1 1 0 Menin Pkinase PF00069.25 GBG62350.1 - 1.9e-57 194.7 1.7 1.2e-41 142.8 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG62350.1 - 2.7e-28 99.0 0.1 5.2e-22 78.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GBG62350.1 - 0.00042 20.3 0.2 0.15 12.0 0.4 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 GBG62350.1 - 0.0044 16.4 0.0 0.11 11.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GBG62350.1 - 0.0078 15.2 0.1 0.014 14.3 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 GBG62350.1 - 0.017 14.2 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 CRA PF06589.11 GBG62350.1 - 0.12 12.5 0.6 0.21 11.7 0.6 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Pkinase_C PF00433.24 GBG62351.1 - 8.5e-08 32.8 0.0 2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain RPN1_C PF18051.1 GBG62352.1 - 2.9e-31 107.3 0.0 6.2e-31 106.2 0.0 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 GBG62352.1 - 5.3e-24 83.4 16.3 0.0001 22.6 0.5 7.7 8 0 0 8 8 8 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GBG62352.1 - 4.2e-08 33.5 0.2 0.047 14.1 0.0 3.8 1 1 3 4 4 4 3 HEAT repeats RPN1_RPN2_N PF17781.1 GBG62353.1 - 5.7e-124 413.5 2.6 7e-124 413.2 2.6 1.1 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain Ribosomal_S8 PF00410.19 GBG62353.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S8 zf-CCHC PF00098.23 GBG62356.1 - 4.6e-05 23.3 3.7 9.3e-05 22.3 3.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG62356.1 - 0.031 14.1 1.7 0.06 13.2 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Fez1 PF06818.15 GBG62356.1 - 0.19 12.2 15.7 0.35 11.3 15.7 1.4 1 0 0 1 1 1 0 Fez1 UPF0270 PF06794.12 GBG62356.1 - 0.25 11.4 3.9 2 8.5 0.2 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0270) FlxA PF14282.6 GBG62356.1 - 1.1 9.3 11.7 0.4 10.7 8.5 1.9 2 0 0 2 2 2 0 FlxA-like protein ALMT PF11744.8 GBG62356.1 - 2.5 6.8 5.8 3.2 6.5 5.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 GBG62356.1 - 3.3 5.5 6.2 3.8 5.3 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.6 GBG62357.1 - 0.00058 19.8 0.4 0.00058 19.8 0.4 2.9 1 1 0 2 2 2 1 FlxA-like protein MCD PF05292.11 GBG62357.1 - 0.16 11.5 4.4 0.21 11.1 3.8 1.4 1 1 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain PSCyt3 PF07627.11 GBG62357.1 - 0.53 10.6 2.9 0.85 9.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) HORMA PF02301.18 GBG62357.1 - 2.7 7.5 5.8 8.8 5.9 5.8 1.9 1 1 0 1 1 1 0 HORMA domain gag-asp_proteas PF13975.6 GBG62359.1 - 0.00057 20.4 0.2 0.0012 19.4 0.2 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62359.1 - 0.00074 20.1 0.1 0.0016 19.0 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG62359.1 - 0.053 13.2 1.2 0.085 12.5 0.1 2.0 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG62359.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease DEK_C PF08766.11 GBG62361.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain CobT PF06213.12 GBG62362.1 - 0.047 13.1 9.1 0.045 13.2 9.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 GBG62362.1 - 0.051 11.7 17.0 0.046 11.8 17.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG62362.1 - 0.062 12.7 10.7 0.058 12.8 10.7 1.1 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 GBG62362.1 - 0.45 10.2 7.8 0.62 9.7 7.8 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 GBG62362.1 - 0.69 8.1 13.2 0.74 8.0 13.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG62362.1 - 0.8 7.8 15.5 0.82 7.8 15.5 1.0 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 GBG62362.1 - 1.1 7.3 10.5 1.2 7.2 10.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Utp14 PF04615.13 GBG62362.1 - 1.4 7.4 10.0 1.5 7.3 10.0 1.0 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 GBG62362.1 - 1.8 7.8 10.0 1.7 7.9 10.0 1.0 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 GBG62362.1 - 3.1 6.8 25.6 3.4 6.7 25.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Myc_N PF01056.18 GBG62362.1 - 3.6 7.4 7.2 4 7.2 7.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PI3K_1B_p101 PF10486.9 GBG62362.1 - 4.1 5.0 4.9 3.8 5.2 4.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFB6 PF17110.5 GBG62362.1 - 5.3 6.8 9.1 6 6.6 9.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4637 PF15470.6 GBG62362.1 - 8.4 6.1 11.1 10 5.8 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RRN3 PF05327.11 GBG62362.1 - 9.1 4.7 12.7 9.5 4.6 12.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Xpo1 PF08389.12 GBG62363.1 - 1.3e-15 57.7 0.0 1.2e-14 54.7 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 GBG62363.1 - 0.00058 19.7 1.1 0.006 16.5 0.4 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain ATP-synt_DE PF00401.20 GBG62363.1 - 0.18 12.1 3.3 0.68 10.2 3.3 2.0 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain TPT PF03151.16 GBG62364.1 - 5.1e-73 245.9 25.6 1.2e-41 143.0 6.8 3.1 1 1 2 3 3 3 3 Triose-phosphate Transporter family EamA PF00892.20 GBG62364.1 - 2.4e-13 50.5 23.9 1.2e-07 32.0 8.5 2.1 1 1 1 2 2 2 2 EamA-like transporter family UAA PF08449.11 GBG62364.1 - 0.0079 15.4 7.2 0.0079 15.4 7.2 1.9 1 1 1 2 2 2 1 UAA transporter family Abhydrolase_9_N PF15420.6 GBG62364.1 - 0.016 15.3 1.5 0.069 13.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF2104 PF09877.9 GBG62364.1 - 0.13 12.6 0.4 0.13 12.6 0.4 2.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2104) DUF4677 PF15726.5 GBG62364.1 - 0.14 12.3 0.4 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) DUF676 PF05057.14 GBG62364.1 - 0.63 9.5 2.1 18 4.8 0.2 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Retrotrans_gag PF03732.17 GBG62365.1 - 0.1 12.9 3.5 0.12 12.7 0.1 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein DUF5032 PF16435.5 GBG62366.1 - 0.057 12.9 0.1 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5032) DUF1833 PF08875.11 GBG62366.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) DUF4211 PF13926.6 GBG62368.1 - 7.5e-11 42.3 0.0 7.5e-11 42.3 0.0 4.2 3 2 0 3 3 3 1 Domain of unknown function (DUF4211) CAP_N PF01213.19 GBG62369.1 - 0.33 10.4 1.1 0.44 10.0 1.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG62369.1 - 1.5 8.9 4.5 2.8 8.0 4.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RVT_1 PF00078.27 GBG62370.1 - 7.4e-30 104.1 0.0 1.2e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62370.1 - 2.1e-24 85.5 0.0 5.6e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62370.1 - 3.4e-22 78.7 0.0 7.8e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62370.1 - 1.9e-17 63.1 0.4 4.3e-17 62.0 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62370.1 - 3.2e-08 33.8 0.0 1e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG62370.1 - 1e-06 29.3 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62370.1 - 1.7e-06 28.5 0.0 3.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62370.1 - 2.3e-05 24.2 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62370.1 - 0.00026 20.8 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Thioredoxin PF00085.20 GBG62372.1 - 1.1e-19 70.4 0.0 1.6e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GBG62372.1 - 0.00099 19.4 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 GBG62372.1 - 0.0035 16.3 0.0 0.0049 15.9 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 GBG62372.1 - 0.053 14.0 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain OST3_OST6 PF04756.13 GBG62372.1 - 0.062 12.6 0.1 0.088 12.1 0.1 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 GBG62372.1 - 0.067 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin T4_deiodinase PF00837.17 GBG62372.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Iodothyronine deiodinase TraF PF13728.6 GBG62372.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 GBG62372.1 - 0.13 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 GBG62372.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like SseB_C PF14581.6 GBG62372.1 - 0.23 11.6 0.0 0.38 10.9 0.0 1.3 1 0 0 1 1 1 0 SseB protein C-terminal domain RVT_1 PF00078.27 GBG62374.1 - 1.6e-33 116.1 0.0 2.9e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62374.1 - 2.6e-19 69.1 0.0 1.6e-18 66.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase GidB PF02527.15 GBG62374.1 - 1.9e-15 56.6 0.0 1.3e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G RT_RNaseH PF17917.1 GBG62374.1 - 3e-08 33.9 0.1 1.9e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG62374.1 - 0.0013 19.0 2.6 0.0019 18.5 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein LsmAD PF06741.13 GBG62375.1 - 0.38 11.3 2.5 0.59 10.7 1.7 1.7 1 1 0 1 1 1 0 LsmAD domain Pkinase PF00069.25 GBG62376.1 - 5.9e-07 29.1 0.0 5.6e-06 25.9 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Leptin PF02024.15 GBG62376.1 - 0.16 11.7 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Leptin eIF-4B PF06273.11 GBG62376.1 - 0.91 8.5 8.4 3 6.8 2.3 2.4 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B Peptidase_M18 PF02127.15 GBG62377.1 - 4.3e-102 342.1 0.1 4.9e-102 341.9 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GBG62377.1 - 2.5e-07 30.0 0.1 4.7e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase DNA_pol3_delta PF06144.13 GBG62378.1 - 3.6e-16 59.4 0.0 7.1e-16 58.5 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 GBG62378.1 - 0.2 12.0 0.1 1.8 9.0 0.0 2.5 2 1 1 3 3 3 0 AAA C-terminal domain CBFD_NFYB_HMF PF00808.23 GBG62379.1 - 1.9e-13 50.5 0.0 3.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GBG62379.1 - 9.1e-05 22.8 1.7 0.00012 22.5 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Aldolase PF01081.19 GBG62380.1 - 2.2e-41 141.4 2.1 3.2e-41 140.9 2.1 1.2 1 0 0 1 1 1 1 KDPG and KHG aldolase adh_short PF00106.25 GBG62383.1 - 2.4e-45 154.4 0.0 7.3e-45 152.8 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG62383.1 - 1e-30 107.0 0.0 1.5e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG62383.1 - 1.4e-07 31.6 0.0 3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GBG62383.1 - 0.098 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding RPAP2_Rtr1 PF04181.13 GBG62383.1 - 0.26 11.7 2.3 0.68 10.3 0.0 2.7 3 0 0 3 3 3 0 Rtr1/RPAP2 family RVT_1 PF00078.27 GBG62384.1 - 6.9e-32 110.7 0.0 1e-27 97.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62384.1 - 5.7e-28 96.9 0.0 6e-27 93.6 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62384.1 - 1.9e-25 89.1 0.0 5e-25 87.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4746 PF15928.5 GBG62384.1 - 5.4 6.4 8.7 9.1 5.6 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) U-box PF04564.15 GBG62385.1 - 9.8e-14 51.3 0.0 2.9e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GBG62385.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 GBG62385.1 - 0.059 13.5 0.1 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein ACPS PF01648.20 GBG62386.1 - 8.2e-12 45.3 0.2 2.9e-11 43.5 0.1 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily DAZAP2 PF11029.8 GBG62386.1 - 0.073 14.0 0.4 0.16 12.9 0.4 1.7 1 1 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Inositol_P PF00459.25 GBG62387.1 - 1.3e-44 152.8 0.0 4.3e-31 108.4 0.0 2.2 1 1 1 2 2 2 2 Inositol monophosphatase family ACCA PF03255.14 GBG62388.1 - 1.2e-53 180.8 0.0 2.5e-53 179.8 0.0 1.5 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 GBG62388.1 - 2.1e-07 30.0 0.0 4.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Carboxyl transferase domain PTS_EIIC_2 PF13303.6 GBG62388.1 - 8.1e-05 21.8 1.9 0.00013 21.1 1.9 1.3 1 0 0 1 1 1 1 Phosphotransferase system, EIIC MdcE PF06833.11 GBG62388.1 - 0.047 13.2 0.1 0.086 12.3 0.1 1.3 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) EzrA PF06160.12 GBG62388.1 - 0.17 10.1 0.4 0.26 9.4 0.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ECH_1 PF00378.20 GBG62388.1 - 0.36 10.1 1.3 1.3 8.2 1.3 1.9 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ACCA PF03255.14 GBG62389.1 - 1.1e-53 180.9 0.0 2.3e-53 180.0 0.0 1.5 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 GBG62389.1 - 2.1e-09 36.6 0.0 2.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 GBG62389.1 - 0.022 14.2 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 GBG62389.1 - 0.065 12.5 0.5 0.12 11.6 0.5 1.5 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase EzrA PF06160.12 GBG62389.1 - 0.16 10.1 0.4 0.24 9.5 0.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA PIH1 PF08190.12 GBG62390.1 - 5.5e-28 97.5 0.0 1e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 GBG62390.1 - 0.0056 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 PIH1 CS-like domain RT_RNaseH_2 PF17919.1 GBG62393.1 - 2.7e-25 88.3 0.0 1.9e-24 85.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62393.1 - 7.9e-25 87.2 0.0 2.3e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62393.1 - 2e-17 63.0 0.2 5e-17 61.8 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62393.1 - 1.6e-08 34.8 0.0 6.1e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG62393.1 - 5.7e-08 32.6 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62393.1 - 3.3e-07 30.9 0.0 7.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62393.1 - 1.2e-05 25.7 0.0 3.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG62393.1 - 4.9e-05 23.0 0.0 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lant_dehydr_N PF04738.13 GBG62393.1 - 0.0016 16.6 0.2 0.0031 15.7 0.2 1.4 1 0 0 1 1 1 1 Lantibiotic dehydratase, N terminus Asp_protease PF09668.10 GBG62393.1 - 0.0031 17.3 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG62394.1 - 1.4e-40 139.1 0.7 9.2e-29 100.5 0.2 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Paf1 PF03985.13 GBG62395.1 - 2.3 7.1 51.1 3 6.8 51.1 1.1 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.12 GBG62395.1 - 8.4 5.7 52.9 11 5.4 52.9 1.0 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG62397.1 - 5.1e-95 317.2 6.1 2.8e-31 108.7 0.1 4.5 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62397.1 - 2.4e-64 213.6 0.0 6.5e-25 87.1 0.0 4.7 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62397.1 - 5.4e-53 177.7 0.0 1.5e-22 79.9 0.0 4.8 4 0 0 4 4 4 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62397.1 - 9.9e-35 118.5 2.1 4.6e-17 61.9 0.8 3.2 2 0 0 2 2 2 2 Integrase zinc binding domain REJ PF02010.15 GBG62397.1 - 2.3e-16 59.6 0.0 1.7e-07 30.4 0.0 3.4 3 0 0 3 3 3 3 REJ domain rve PF00665.26 GBG62397.1 - 9.7e-12 45.1 0.0 7.7e-11 42.2 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG62397.1 - 1.3e-11 44.6 11.6 0.0029 17.9 0.4 6.5 5 0 0 5 5 5 3 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG62397.1 - 0.00021 21.5 0.0 0.74 10.1 0.0 3.0 2 0 0 2 2 2 2 H2C2 zinc finger RVP_2 PF08284.11 GBG62397.1 - 0.00033 20.4 0.0 0.035 13.9 0.0 2.6 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62397.1 - 0.00047 20.8 0.0 0.59 10.8 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease Lipin_mid PF16876.5 GBG62397.1 - 0.068 13.3 0.0 7.6 6.7 0.0 2.9 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain gag-asp_proteas PF13975.6 GBG62397.1 - 0.1 13.2 0.0 1 10.0 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF659 PF04937.15 GBG62398.1 - 4.1e-33 114.4 0.0 6.9e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG62398.1 - 0.19 11.7 3.5 0.51 10.4 0.7 2.8 2 0 0 2 2 2 0 AT hook motif DUF4683 PF15735.5 GBG62398.1 - 1.9 8.1 7.4 0.096 12.3 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4683) TFIIF_beta_N PF17683.1 GBG62398.1 - 7.5 7.2 7.5 3.3 8.4 0.5 3.0 3 1 0 3 3 3 0 TFIIF, beta subunit N-terminus LigB PF02900.18 GBG62399.1 - 7.7e-52 176.0 0.0 8.7e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase TauD PF02668.16 GBG62400.1 - 0.027 14.3 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Paramecium_SA PF01508.16 GBG62404.1 - 0.0046 17.4 7.3 0.0046 17.4 7.3 4.4 3 2 0 3 3 3 2 Paramecium surface antigen domain Paramecium_SA PF01508.16 GBG62405.1 - 0.0046 17.4 7.3 0.0046 17.4 7.3 4.4 3 2 0 3 3 3 2 Paramecium surface antigen domain zf-C2H2_2 PF12756.7 GBG62406.1 - 6.2e-30 103.5 15.1 1.7e-26 92.5 3.4 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GBG62406.1 - 1.2e-06 28.7 2.6 1.2e-06 28.7 2.6 4.1 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GBG62406.1 - 3.3e-06 27.3 9.7 6.9e-05 23.1 4.6 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GBG62406.1 - 0.054 14.3 0.4 0.054 14.3 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GBG62406.1 - 0.4 10.7 7.7 0.22 11.6 2.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.12 GBG62406.1 - 5.8 5.3 21.2 0.76 8.2 0.6 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF629) RT_RNaseH_2 PF17919.1 GBG62408.1 - 3e-30 104.2 0.0 1.8e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62408.1 - 1.5e-29 103.2 0.0 2.5e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62408.1 - 2.4e-28 98.5 0.0 4.9e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LOB PF03195.14 GBG62410.1 - 2.4e-43 146.7 0.5 3.9e-43 146.0 0.5 1.3 1 0 0 1 1 1 1 Lateral organ boundaries (LOB) domain RVT_1 PF00078.27 GBG62411.1 - 1.8e-28 99.6 0.0 2.6e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG62411.1 - 7.8e-12 44.9 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1990 PF09348.10 GBG62412.1 - 2.6e-12 47.1 0.3 5.5e-12 46.0 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1990) TMEM191C PF15194.6 GBG62413.1 - 0.052 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 TMEM191C family gag-asp_proteas PF13975.6 GBG62414.1 - 1.6e-07 31.8 0.1 6.2e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62414.1 - 4.3e-05 24.1 0.1 0.00014 22.5 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62414.1 - 0.00023 20.9 0.1 0.00038 20.3 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG62414.1 - 0.066 12.9 0.3 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG62414.1 - 0.26 11.4 5.2 0.058 13.5 1.9 1.7 2 0 0 2 2 2 0 Zinc knuckle Asp_protease_2 PF13650.6 GBG62415.1 - 6.4e-05 23.5 0.1 0.01 16.4 0.0 3.2 3 0 0 3 3 3 1 Aspartyl protease RVP_2 PF08284.11 GBG62415.1 - 0.0021 17.8 0.0 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG62415.1 - 0.0093 16.5 0.0 0.052 14.1 0.0 2.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2385 PF09539.10 GBG62415.1 - 0.033 14.7 0.1 0.86 10.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) HALZ PF02183.18 GBG62415.1 - 0.089 13.0 1.2 0.24 11.7 1.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 GBG62415.1 - 1.2 9.6 6.1 0.36 11.3 1.8 2.3 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 GBG62415.1 - 1.7 8.8 7.8 0.089 12.9 2.1 1.9 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 GBG62415.1 - 1.7 8.5 5.7 0.39 10.5 1.9 1.9 2 0 0 2 2 2 0 Septum formation initiator RT_RNaseH_2 PF17919.1 GBG62416.1 - 3.8e-32 110.3 0.0 9.8e-32 109.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62416.1 - 6.7e-29 100.3 0.1 1.5e-28 99.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62416.1 - 8.2e-21 74.5 0.1 1.7e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG62416.1 - 4.4e-07 30.4 0.0 1.5e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62416.1 - 1.5e-05 25.6 0.0 4.4e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG62416.1 - 0.0016 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG62416.1 - 0.064 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62416.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease LMBR1 PF04791.16 GBG62417.1 - 0.37 9.6 11.0 3.7 6.3 9.9 2.1 1 1 1 2 2 2 0 LMBR1-like membrane protein RT_RNaseH_2 PF17919.1 GBG62418.1 - 1.3e-63 211.3 0.4 3.6e-30 103.9 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62418.1 - 5.7e-60 200.1 2.5 3.2e-29 101.3 0.0 3.5 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62418.1 - 1.9e-16 60.3 0.1 1.2e-15 57.8 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG62418.1 - 6e-15 55.1 0.1 1.3e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG62419.1 - 4.5e-31 106.8 0.0 2.8e-30 104.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62419.1 - 2.2e-30 105.0 0.3 2.4e-29 101.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62419.1 - 3.5e-16 59.5 0.0 8.9e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG62419.1 - 4.7e-15 55.4 0.1 1e-14 54.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Presenilin PF01080.17 GBG62420.1 - 0.017 13.9 2.7 0.87 8.3 0.0 2.3 2 0 0 2 2 2 0 Presenilin AAA_11 PF13086.6 GBG62420.1 - 3.8 7.2 10.9 0.96 9.2 0.9 2.1 2 0 0 2 2 2 0 AAA domain SDA1 PF05285.12 GBG62420.1 - 4.5 6.6 27.2 1.7 8.0 7.5 2.3 2 0 0 2 2 2 0 SDA1 Presenilin PF01080.17 GBG62421.1 - 0.41 9.4 1.7 0.51 9.1 1.7 1.2 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG62422.1 - 2.2e-05 24.4 0.0 4.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62422.1 - 0.00025 21.3 0.0 0.00051 20.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62423.1 - 1.2e-22 79.8 0.0 6.4e-22 77.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62423.1 - 5.9e-21 74.7 0.0 1.2e-19 70.5 0.0 3.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62423.1 - 1.1e-13 51.4 0.0 2.6e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG62423.1 - 2.7e-13 49.8 0.0 6.3e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG62423.1 - 0.00023 20.7 0.0 0.00051 19.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG62423.1 - 0.063 13.6 0.1 0.063 13.6 0.1 2.5 2 1 1 3 3 3 0 Retrotransposon gag protein Strep_SA_rep PF06696.11 GBG62423.1 - 0.1 12.6 0.4 0.43 10.6 0.4 2.1 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DUF659 PF04937.15 GBG62424.1 - 5.5e-06 26.3 0.0 9.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Poty_PP PF08440.10 GBG62426.1 - 0.0099 15.0 3.5 1.2 8.2 0.3 2.2 2 0 0 2 2 2 2 Potyviridae polyprotein RVT_1 PF00078.27 GBG62427.1 - 2e-30 106.0 0.6 3.8e-30 105.1 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62427.1 - 3.6e-24 85.1 0.0 1.1e-23 83.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62427.1 - 2.7e-23 81.9 0.0 7.1e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62427.1 - 5.5e-19 68.0 0.2 1.2e-18 67.0 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG62427.1 - 3.6e-08 33.3 0.0 7.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62427.1 - 4.5e-08 33.6 0.0 9.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62427.1 - 7.2e-06 26.5 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG62427.1 - 0.0013 18.5 0.0 0.0042 16.9 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG62427.1 - 0.0026 17.6 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG62429.1 - 1.1e-31 109.7 0.0 1.9e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62429.1 - 1.5e-12 47.5 0.0 3.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG62429.1 - 1.5e-05 24.8 0.0 0.51 9.9 0.0 3.3 3 0 0 3 3 3 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG62430.1 - 1.3e-05 25.5 0.6 0.00032 21.0 0.3 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG62430.1 - 0.032 14.3 0.6 0.032 14.3 0.6 1.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain rve PF00665.26 GBG62431.1 - 5.6e-13 49.1 0.1 2.1e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG62431.1 - 1.1e-10 41.4 0.0 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG62431.1 - 0.017 14.8 0.0 0.069 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) ComX PF05952.12 GBG62433.1 - 0.14 12.2 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Bacillus competence pheromone ComX CDC45 PF02724.14 GBG62433.1 - 0.33 9.2 9.2 0.3 9.3 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG62433.1 - 0.86 7.7 15.3 0.86 7.7 15.3 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 GBG62433.1 - 1.6 7.8 25.2 2.2 7.3 25.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid_p PF12226.8 GBG62433.1 - 5.2 6.1 13.9 5.4 6.1 13.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein WRNPLPNID PF15017.6 GBG62433.1 - 9.7 7.2 18.3 1.5 9.7 13.6 2.0 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box RT_RNaseH_2 PF17919.1 GBG62434.1 - 5.5e-13 48.8 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62434.1 - 2.2e-11 43.7 0.1 3.6e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG62434.1 - 0.97 7.6 6.8 1.3 7.2 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG62434.1 - 6.1 4.9 8.7 7.5 4.6 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 GBG62435.1 - 0.7 8.7 5.3 0.62 8.9 5.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 GBG62435.1 - 2.1 8.3 9.4 2.6 8.0 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Secretin_N_2 PF07655.13 GBG62435.1 - 6.7 7.3 19.7 9.4 6.9 19.7 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.9 GBG62435.1 - 7.8 4.9 12.1 7.9 4.9 12.1 1.0 1 0 0 1 1 1 0 Macoilin family RVT_1 PF00078.27 GBG62436.1 - 9.8e-24 84.1 0.1 1.5e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62436.1 - 3.4e-12 46.3 0.1 1.1e-11 44.7 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG62436.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease TB2_DP1_HVA22 PF03134.19 GBG62437.1 - 0.06 13.3 0.1 0.085 12.8 0.1 1.2 1 0 0 1 1 1 0 TB2/DP1, HVA22 family RVT_1 PF00078.27 GBG62438.1 - 7e-36 123.8 0.0 1.2e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62438.1 - 3.2e-29 100.9 0.0 9.7e-29 99.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62438.1 - 2.8e-28 98.3 0.0 7.3e-28 96.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG62438.1 - 0.00013 21.8 0.0 0.00036 20.3 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG62439.1 - 6.9e-36 123.8 0.0 1.2e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62439.1 - 3.1e-29 101.0 0.0 9.3e-29 99.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62439.1 - 2.6e-28 98.4 0.0 7e-28 97.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG62439.1 - 0.00012 21.8 0.0 0.00034 20.4 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG62440.1 - 6.5e-28 96.7 0.0 1.4e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62440.1 - 2.8e-22 79.0 0.0 6.1e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG62440.1 - 3.9e-05 23.9 0.4 0.0015 18.8 0.0 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein APG17 PF04108.12 GBG62440.1 - 0.057 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 RVT_1 PF00078.27 GBG62441.1 - 1.7e-32 112.7 0.0 2.3e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1633 PF07794.11 GBG62442.1 - 0.004 15.4 0.8 0.007 14.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1633) TcpS PF17456.2 GBG62442.1 - 0.097 12.7 0.4 0.18 11.9 0.4 1.3 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S Tropomyosin_1 PF12718.7 GBG62442.1 - 2.9 8.1 8.0 0.2 11.8 0.9 2.3 2 1 1 3 3 3 0 Tropomyosin like adh_short PF00106.25 GBG62443.1 - 8e-22 77.6 0.2 1.1e-21 77.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG62443.1 - 6.8e-19 68.3 0.4 8.8e-19 68.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 GBG62443.1 - 0.0063 17.1 0.0 0.012 16.2 0.0 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GBG62443.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase rve PF00665.26 GBG62444.1 - 8.4e-12 45.3 0.0 2.5e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG62444.1 - 3e-11 43.1 0.0 5.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG62444.1 - 0.0055 17.3 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease NIF PF03031.18 GBG62445.1 - 8.4e-51 171.8 0.1 1.6e-50 170.9 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RT_RNaseH_2 PF17919.1 GBG62445.1 - 7.4e-23 80.5 0.7 1.7e-22 79.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62445.1 - 1.2e-18 67.3 0.0 3.1e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62445.1 - 2.3e-16 59.6 0.4 4.9e-16 58.6 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG62445.1 - 9.9e-10 38.3 0.0 3e-07 30.2 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MscS_TM PF12794.7 GBG62445.1 - 5.2 5.8 5.0 75 2.0 5.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 CLTH PF10607.9 GBG62446.1 - 1.3e-34 119.2 0.0 2.7e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 GBG62446.1 - 1.1e-21 77.1 0.0 1.8e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 GBG62446.1 - 2.8e-08 33.4 0.1 6.4e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 LisH Retrotrans_gag PF03732.17 GBG62446.1 - 0.046 14.0 0.2 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein NPV_P10 PF05531.12 GBG62446.1 - 0.12 12.8 0.7 0.94 10.0 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Complex1_51K PF01512.17 GBG62447.1 - 8e-48 162.2 0.0 1.3e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 GBG62447.1 - 2.1e-28 98.2 0.3 4.8e-28 97.1 0.3 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 GBG62447.1 - 8.7e-08 31.9 0.0 2.3e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 SLBB domain Histone PF00125.24 GBG62451.1 - 1.6e-13 51.1 0.7 1.6e-13 51.1 0.7 2.7 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG62451.1 - 0.096 13.1 0.2 0.37 11.2 0.2 2.0 1 0 0 1 1 1 0 CENP-S protein DUF4332 PF14229.6 GBG62452.1 - 2.7e-29 101.9 0.1 3e-29 101.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) HHH_5 PF14520.6 GBG62452.1 - 7e-06 26.6 0.1 0.024 15.2 0.1 2.2 1 1 1 2 2 2 2 Helix-hairpin-helix domain Cdd1 PF11731.8 GBG62452.1 - 0.00013 22.2 0.0 0.0027 17.9 0.0 2.1 2 0 0 2 2 2 1 Pathogenicity locus DUF1018 PF06252.12 GBG62452.1 - 0.036 15.0 0.0 0.064 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) TfoX_C PF04994.13 GBG62452.1 - 0.12 12.5 0.1 0.95 9.6 0.0 2.2 2 1 0 2 2 2 0 TfoX C-terminal domain Na_trans_assoc PF06512.13 GBG62453.1 - 0.0078 16.5 10.8 0.015 15.6 10.8 1.6 1 0 0 1 1 1 1 Sodium ion transport-associated SAPS PF04499.15 GBG62453.1 - 0.96 8.2 8.7 1.5 7.5 8.3 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PXPV PF12778.7 GBG62453.1 - 1.3 9.0 11.4 3.1 7.7 11.4 1.6 1 0 0 1 1 1 0 PXPV repeat (3 copies) Nop14 PF04147.12 GBG62453.1 - 2.9 6.0 32.9 5.6 5.0 32.9 1.4 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG62453.1 - 5.9 6.2 33.4 9.6 5.5 33.4 1.2 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 GBG62453.1 - 7.7 5.5 14.2 14 4.6 14.2 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4332 PF14229.6 GBG62456.1 - 8.7e-29 100.2 0.1 9.7e-29 100.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) HHH_5 PF14520.6 GBG62456.1 - 3.7e-06 27.4 0.1 0.012 16.2 0.1 2.2 1 1 1 2 2 2 2 Helix-hairpin-helix domain Cdd1 PF11731.8 GBG62456.1 - 0.00018 21.6 0.0 0.0028 17.8 0.0 2.1 2 0 0 2 2 2 1 Pathogenicity locus DUF1018 PF06252.12 GBG62456.1 - 0.035 15.1 0.0 0.067 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) TPR_2 PF07719.17 GBG62457.1 - 5e-10 38.7 12.3 4e-05 23.4 2.4 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG62457.1 - 2e-09 36.9 10.8 5.6e-06 25.9 1.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 GBG62457.1 - 7.9e-07 29.1 1.3 4.9e-06 26.6 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG62457.1 - 2.5e-06 28.0 1.6 2.5e-06 28.0 1.6 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG62457.1 - 6e-06 25.8 17.0 0.019 14.6 0.2 4.1 3 1 1 4 4 4 3 TPR repeat TPR_8 PF13181.6 GBG62457.1 - 0.00089 19.3 10.8 0.0013 18.8 0.7 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG62457.1 - 0.005 17.1 0.4 0.12 12.9 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG62457.1 - 0.0051 17.3 4.4 0.0051 17.3 4.4 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat Sigma54_CBD PF04963.13 GBG62457.1 - 0.0066 16.3 1.1 2.2 8.1 0.0 3.2 3 1 0 3 3 3 1 Sigma-54 factor, core binding domain DUF2624 PF11116.8 GBG62457.1 - 0.031 15.2 0.4 0.83 10.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) TPR_6 PF13174.6 GBG62457.1 - 0.077 13.7 9.6 0.18 12.5 1.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 GBG62457.1 - 0.15 11.7 17.7 0.35 10.6 13.4 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain DUF4919 PF16266.5 GBG62457.1 - 0.43 10.5 0.0 0.43 10.5 0.0 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4919) DUF4423 PF14394.6 GBG62457.1 - 0.99 9.1 13.9 1.7 8.4 1.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4423) TPR_12 PF13424.6 GBG62457.1 - 2.3 8.6 12.5 8.6 6.7 2.8 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat PIN_4 PF13638.6 GBG62458.1 - 1.6e-13 51.1 0.1 1.3e-10 41.7 0.0 2.9 2 1 0 2 2 2 1 PIN domain PIN_9 PF18477.1 GBG62458.1 - 0.017 15.4 0.0 0.065 13.5 0.0 2.0 1 0 0 1 1 1 0 PIN like domain NYN_YacP PF05991.11 GBG62458.1 - 0.036 14.0 1.3 0.47 10.4 0.0 2.8 2 1 1 3 3 3 0 YacP-like NYN domain Sigma70_ner PF04546.13 GBG62458.1 - 1.7 8.5 16.9 0.37 10.6 11.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Voldacs PF03517.13 GBG62458.1 - 3.2 7.9 13.3 0.63 10.2 6.7 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling RRN3 PF05327.11 GBG62458.1 - 3.2 6.2 11.7 4.8 5.6 11.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RCC1 PF00415.18 GBG62459.1 - 8.6e-80 263.2 29.4 1.1e-16 61.2 0.1 8.5 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG62459.1 - 1.8e-48 161.4 35.5 3e-08 33.3 0.2 8.3 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Acetyltransf_14 PF03421.16 GBG62459.1 - 0.049 13.7 0.0 59 3.7 0.0 3.6 4 0 0 4 4 4 0 YopJ Serine/Threonine acetyltransferase N6_N4_Mtase PF01555.18 GBG62460.1 - 8.1e-05 22.4 0.0 8.1e-05 22.4 0.0 3.0 3 0 0 3 3 3 1 DNA methylase Nop14 PF04147.12 GBG62460.1 - 0.00011 20.6 9.3 0.00011 20.6 9.3 3.3 4 0 0 4 4 4 2 Nop14-like family Ribosomal_L50 PF10501.9 GBG62460.1 - 0.005 17.0 0.2 2.4 8.3 0.0 3.8 3 0 0 3 3 3 1 Ribosomal subunit 39S YL1 PF05764.13 GBG62460.1 - 0.0058 16.8 10.7 0.0058 16.8 10.7 5.6 4 2 0 4 4 4 1 YL1 nuclear protein Toxin_37 PF11415.8 GBG62460.1 - 2.8 7.8 7.9 2.5 8.0 0.4 3.1 3 0 0 3 3 3 0 Antifungal peptide termicin ADC PF06314.11 GBG62461.1 - 0.15 11.6 1.1 0.2 11.2 1.1 1.1 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) DDE_Tnp_4 PF13359.6 GBG62463.1 - 2.3e-25 89.1 0.0 3.6e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62463.1 - 7.2e-12 45.3 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG62463.1 - 0.048 13.3 0.2 0.17 11.5 0.0 2.0 3 0 0 3 3 3 0 Transposase DDE domain RVT_1 PF00078.27 GBG62464.1 - 2.9e-25 89.1 0.1 5e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62464.1 - 3e-18 65.7 0.0 7e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62464.1 - 4.3e-10 39.8 0.0 1.6e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG62464.1 - 1.3e-06 28.7 0.1 1.2e-05 25.6 0.3 2.5 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain TolA_bind_tri PF16331.5 GBG62464.1 - 0.011 15.8 5.3 0.037 14.1 5.3 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation MADF_DNA_bdg PF10545.9 GBG62464.1 - 0.16 12.3 1.4 0.32 11.3 0.1 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Phage_GPO PF05929.11 GBG62464.1 - 0.18 11.4 4.4 2.7 7.6 3.1 2.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG62465.1 - 2.9e-30 104.3 0.0 6.1e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62465.1 - 3e-27 95.6 0.0 1e-26 93.8 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62465.1 - 8.1e-27 93.6 0.0 1.9e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PAXNEB PF05625.11 GBG62465.1 - 1.3e-22 80.5 0.0 2.3e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 PAXNEB protein Integrase_H2C2 PF17921.1 GBG62465.1 - 3.3e-18 65.6 0.2 9.4e-18 64.1 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62465.1 - 9.1e-10 38.8 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG62465.1 - 8.8e-08 32.0 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62465.1 - 0.0048 17.5 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62465.1 - 0.0048 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG62465.1 - 0.02 15.2 0.1 0.083 13.2 0.1 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein DUF659 PF04937.15 GBG62466.1 - 1.7e-27 96.2 0.0 3e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG62466.1 - 1.3e-06 28.1 0.3 2.7e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG62467.1 - 3.1e-26 91.3 0.0 8.4e-26 89.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62467.1 - 1.1e-22 80.2 0.0 3.7e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62467.1 - 3.9e-11 42.9 0.2 5.6e-11 42.4 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sporozoite_P67 PF05642.11 GBG62468.1 - 2.2 6.3 12.2 2.9 5.9 12.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.17 GBG62468.1 - 5 5.8 8.5 7.2 5.3 8.5 1.3 1 0 0 1 1 1 0 Presenilin Histone PF00125.24 GBG62469.1 - 2.1e-15 57.2 0.0 5.4e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Nuc_N PF14448.6 GBG62470.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Nuclease N terminal Auto_anti-p27 PF06677.12 GBG62471.1 - 2.8e-15 56.2 1.7 5.4e-15 55.3 1.7 1.5 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) FKBP_C PF00254.28 GBG62473.1 - 9.3e-24 83.6 0.0 1.6e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Oleosin PF01277.17 GBG62474.1 - 3.1e-10 39.8 10.5 3.1e-10 39.8 10.5 2.3 2 1 0 2 2 2 1 Oleosin DUF4605 PF15378.6 GBG62474.1 - 0.014 15.3 4.1 0.014 15.3 4.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) ABC2_membrane_3 PF12698.7 GBG62474.1 - 0.019 14.1 6.5 0.026 13.7 6.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein FtsX PF02687.21 GBG62474.1 - 0.24 11.9 11.9 0.38 11.2 11.9 1.2 1 0 0 1 1 1 0 FtsX-like permease family DUF2207 PF09972.9 GBG62474.1 - 0.27 10.0 3.5 0.64 8.7 3.5 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.8 GBG62474.1 - 0.36 10.7 5.8 0.075 12.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Ribonuc_red_lgC PF02867.15 GBG62475.1 - 2.9e-11 42.6 4.8 0.0015 17.2 1.3 3.6 2 2 1 4 4 4 3 Ribonucleotide reductase, barrel domain RNR_Alpha PF17975.1 GBG62475.1 - 0.00044 20.7 3.3 0.0012 19.4 0.3 2.9 3 0 0 3 3 3 1 Ribonucleotide reductase alpha domain Cyt-b5 PF00173.28 GBG62476.1 - 3.3e-10 40.0 0.0 5.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AD PF09793.9 GBG62477.1 - 2.8e-24 85.1 0.0 3.7e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 GBG62477.1 - 0.0039 16.8 0.0 0.053 13.1 0.0 2.1 1 1 0 1 1 1 1 Gemin6 protein SGS PF05002.15 GBG62479.1 - 2.8e-34 117.1 2.8 5.4e-34 116.2 2.8 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 GBG62479.1 - 2.8e-14 53.9 0.0 5.8e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 GBG62479.1 - 9.5e-10 37.9 3.6 0.0015 18.2 0.1 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG62479.1 - 1.7e-08 34.0 3.0 0.002 18.1 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG62479.1 - 6.6e-08 32.1 2.2 9.9e-05 21.9 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 GBG62479.1 - 2.6e-07 31.0 0.2 0.0034 17.8 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG62479.1 - 1.7e-06 27.8 2.3 0.0057 16.8 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG62479.1 - 3.4e-06 27.6 2.5 0.0069 17.0 1.6 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG62479.1 - 7.1e-06 26.4 0.4 0.42 11.5 0.1 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG62479.1 - 3.7e-05 23.8 0.2 0.3 11.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG62479.1 - 0.0012 19.4 2.1 1.7 9.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GBG62479.1 - 0.0029 17.7 0.1 0.95 9.7 0.0 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG62479.1 - 0.0049 16.8 0.6 5.2 7.3 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3507 PF12015.8 GBG62479.1 - 0.0083 15.8 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3507) Cas_Cas02710 PF09670.10 GBG62479.1 - 0.11 11.3 1.0 0.62 8.8 0.3 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas02710) Bac_rhamnosid6H PF17389.2 GBG62479.1 - 0.11 11.8 0.2 0.38 9.9 0.1 1.8 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain MRP-S35 PF10246.9 GBG62479.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 Fis1_TPR_C PF14853.6 GBG62479.1 - 0.15 12.1 0.4 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat WD40 PF00400.32 GBG62480.1 - 3.7e-05 24.4 11.0 0.095 13.6 0.1 4.1 4 0 0 4 4 3 2 WD domain, G-beta repeat DUF2722 PF10846.8 GBG62480.1 - 3.7e-05 22.9 7.1 4.2e-05 22.7 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 GBG62480.1 - 0.028 14.4 15.1 0.04 13.9 15.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 GBG62480.1 - 0.11 10.4 13.8 0.14 10.0 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) eIF-3_zeta PF05091.12 GBG62480.1 - 0.36 9.7 8.0 0.51 9.3 8.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 GBG62480.1 - 0.37 9.5 4.1 0.5 9.1 4.1 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 GBG62480.1 - 0.7 9.5 26.1 1.1 8.8 26.1 1.2 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 GBG62480.1 - 1.1 9.9 12.5 1.8 9.2 12.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4770 PF15994.5 GBG62480.1 - 1.6 8.9 8.9 2.5 8.3 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4834 PF16118.5 GBG62480.1 - 3.3 8.7 11.1 5.9 7.9 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 GBG62480.1 - 4.8 6.0 25.5 6.9 5.5 25.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ribosomal_S20p PF01649.18 GBG62481.1 - 1.7e-20 73.4 3.4 3.3e-20 72.5 3.4 1.4 1 1 0 1 1 1 1 Ribosomal protein S20 RPW8 PF05659.11 GBG62481.1 - 0.029 14.1 0.1 0.051 13.3 0.1 1.5 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Ribosomal_S20p PF01649.18 GBG62482.1 - 3.3e-20 72.5 8.0 4.6e-20 72.0 8.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S20 RPW8 PF05659.11 GBG62482.1 - 0.0066 16.1 0.7 0.0094 15.6 0.7 1.2 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 CpeT PF06206.11 GBG62483.1 - 1.8e-41 142.1 0.0 2.4e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) Y_phosphatase2 PF03162.13 GBG62484.1 - 1.2e-43 148.6 0.0 1.4e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GBG62484.1 - 0.015 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Thi4 PF01946.17 GBG62485.1 - 3.3e-113 376.7 1.5 4.4e-113 376.3 1.5 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 GBG62485.1 - 2.2e-09 37.4 2.1 3.2e-08 33.6 0.7 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GBG62485.1 - 2.5e-08 34.0 0.2 8.2e-08 32.4 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GBG62485.1 - 4.5e-07 29.3 10.2 6.4e-07 28.8 0.4 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 GBG62485.1 - 5.1e-06 25.9 0.1 6.9e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GBG62485.1 - 3.7e-05 22.9 0.1 5.1e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 GBG62485.1 - 7.2e-05 22.3 0.2 0.00014 21.3 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 GBG62485.1 - 0.00021 20.8 0.1 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_9 PF13454.6 GBG62485.1 - 0.00032 20.7 0.1 0.0014 18.6 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 GBG62485.1 - 0.00042 19.2 0.2 0.00065 18.5 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 GBG62485.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GBG62485.1 - 0.0025 17.1 0.1 0.0044 16.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GBG62485.1 - 0.0039 16.3 0.1 0.061 12.4 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A RNA_pol_Rpb1_3 PF04983.18 GBG62485.1 - 0.0044 17.0 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 B12D PF06522.11 GBG62485.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Amino_oxidase PF01593.24 GBG62485.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase AD PF09793.9 GBG62486.1 - 1.6e-25 89.0 0.0 2.1e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 GBG62486.1 - 0.0045 16.5 0.0 0.063 12.8 0.0 2.1 1 1 0 1 1 1 1 Gemin6 protein DNA_pol_B PF00136.21 GBG62487.1 - 3.8e-86 289.6 0.7 1.5e-85 287.6 0.0 2.2 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GBG62487.1 - 2.3e-30 105.9 0.0 7.5e-29 100.9 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain RVT_1 PF00078.27 GBG62487.1 - 2.6e-30 105.6 0.3 1e-28 100.4 0.0 2.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_alpha_N PF12254.8 GBG62487.1 - 4.1e-15 55.6 4.0 4.1e-15 55.6 4.0 3.3 2 1 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Asp_protease_2 PF13650.6 GBG62487.1 - 1.1e-05 26.0 0.0 3.4e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62487.1 - 3.7e-05 24.2 0.0 0.00012 22.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62487.1 - 5.2e-05 23.0 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG62487.1 - 0.0012 19.0 0.5 0.0069 16.6 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG62487.1 - 0.0032 17.3 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DNA_pol_B_2 PF03175.13 GBG62487.1 - 0.018 13.9 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral NPV_P10 PF05531.12 GBG62487.1 - 0.32 11.5 2.8 1.2 9.7 0.5 3.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF659 PF04937.15 GBG62488.1 - 6.3e-31 107.3 0.0 1.1e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pox_Ag35 PF03286.14 GBG62488.1 - 6.1 6.6 17.8 16 5.2 17.8 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein gag-asp_proteas PF13975.6 GBG62489.1 - 2.4e-06 28.0 0.0 3.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62489.1 - 4.9e-05 23.9 0.0 8.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62489.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG62489.1 - 0.042 13.6 0.1 0.082 12.7 0.0 1.4 2 0 0 2 2 2 0 Putative peptidase (DUF1758) zf-DNA_Pol PF08996.10 GBG62490.1 - 4.2e-37 127.7 0.0 7.6e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger RT_RNaseH_2 PF17919.1 GBG62490.1 - 1.9e-33 114.4 0.1 4.7e-33 113.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62490.1 - 1e-30 106.1 0.1 2.7e-30 104.8 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DNA_pol_B PF00136.21 GBG62490.1 - 2e-19 69.6 0.0 3.1e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B Integrase_H2C2 PF17921.1 GBG62490.1 - 3.5e-17 62.2 0.1 7.6e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62490.1 - 1.6e-14 54.1 0.0 5.5e-14 52.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Allene_ox_cyc PF06351.11 GBG62490.1 - 0.03 14.1 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Allene oxide cyclase zf-H2C2 PF09337.10 GBG62490.1 - 0.1 12.8 0.0 0.39 11.0 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger REV PF00424.18 GBG62491.1 - 0.066 13.2 0.6 0.066 13.2 0.6 2.7 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF3138 PF11336.8 GBG62491.1 - 0.25 9.9 2.3 0.3 9.7 1.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2950 PF11453.8 GBG62491.1 - 0.32 10.2 11.3 0.43 9.7 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Herpes_UL25 PF01499.16 GBG62491.1 - 1.8 7.0 8.1 3.1 6.2 8.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Uso1_p115_C PF04871.13 GBG62491.1 - 3.1 8.2 34.9 1.3 9.4 7.6 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Peptidase_S46 PF10459.9 GBG62491.1 - 3.1 6.3 22.8 4.6 5.8 22.8 1.2 1 0 0 1 1 1 0 Peptidase S46 Pkinase PF00069.25 GBG62492.1 - 8.6e-19 67.9 0.0 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG62492.1 - 2.9e-06 26.8 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG62492.1 - 0.0051 15.7 0.0 0.0086 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase hnRNP_Q_AcD PF18360.1 GBG62492.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF5634_N PF18672.1 GBG62492.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5634) Pkinase PF00069.25 GBG62493.1 - 8.6e-19 67.9 0.0 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG62493.1 - 2.9e-06 26.8 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG62493.1 - 0.0051 15.6 0.0 0.0086 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase hnRNP_Q_AcD PF18360.1 GBG62493.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF5634_N PF18672.1 GBG62493.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5634) DpnD-PcfM PF14207.6 GBG62494.1 - 0.15 12.0 2.2 0.39 10.6 2.2 1.7 1 0 0 1 1 1 0 DpnD/PcfM-like protein NOC3p PF07540.11 GBG62495.1 - 1.7e-29 102.1 0.0 5e-29 100.6 0.0 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 GBG62495.1 - 2.2e-20 73.4 0.0 2.2e-20 73.4 0.0 2.9 4 0 0 4 4 4 1 CBF/Mak21 family DDE_Tnp_4 PF13359.6 GBG62496.1 - 4.3e-22 78.5 0.0 7.1e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62496.1 - 1.4e-10 41.1 0.0 2.6e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein PHC2_SAM_assoc PF16616.5 GBG62496.1 - 0.029 15.2 1.4 0.029 15.2 1.4 2.0 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DDE_Tnp_1 PF01609.21 GBG62496.1 - 0.45 10.1 1.6 2.3 7.8 0.0 2.7 3 0 0 3 3 3 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG62497.1 - 9.5e-08 32.3 6.2 1.7e-07 31.5 3.1 2.7 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain bPH_6 PF10756.9 GBG62497.1 - 0.0076 16.3 0.5 0.22 11.7 0.0 3.0 2 0 0 2 2 2 1 Bacterial PH domain Cwf_Cwc_15 PF04889.12 GBG62497.1 - 0.07 12.9 10.5 0.14 11.8 10.5 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MADF_DNA_bdg PF10545.9 GBG62497.1 - 0.079 13.3 2.6 0.092 13.1 0.4 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG62497.1 - 0.21 11.8 0.9 0.76 10.0 0.9 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sigma70_ner PF04546.13 GBG62497.1 - 0.27 11.1 4.7 1.2 8.9 3.5 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region GCIP PF13324.6 GBG62497.1 - 0.68 9.5 4.4 1.7 8.2 4.4 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 GBG62497.1 - 0.83 8.9 14.9 1.6 8.0 14.9 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GBG62497.1 - 2.9 6.1 6.0 5.5 5.2 6.0 1.4 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG62497.1 - 3.2 7.8 10.6 2.2 8.3 7.9 1.9 2 0 0 2 2 2 0 YL1 nuclear protein PPP4R2 PF09184.11 GBG62497.1 - 5.2 6.6 6.3 9.1 5.8 6.3 1.3 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 GBG62497.1 - 5.2 5.5 8.1 7.5 5.0 6.9 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GBG62497.1 - 8 4.4 19.6 12 3.9 19.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RVT_3 PF13456.6 GBG62499.1 - 1.5e-19 70.0 0.0 2.6e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 GBG62499.1 - 1.7e-06 28.3 0.0 2.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNase H Glyco_transf_29 PF00777.18 GBG62500.1 - 8e-31 107.4 0.0 1.2e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) EGF_2 PF07974.13 GBG62500.1 - 4e-10 39.9 63.5 0.026 14.9 11.6 5.5 3 1 2 5 5 5 5 EGF-like domain RT_RNaseH_2 PF17919.1 GBG62501.1 - 1e-26 92.9 0.0 1.7e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62501.1 - 2.2e-19 69.7 0.0 4.1e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62501.1 - 1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG62501.1 - 0.95 7.6 8.0 1.3 7.2 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG62501.1 - 1.8 7.9 8.1 2.5 7.4 8.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG62501.1 - 3.4 5.8 6.2 4.5 5.4 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH PF17917.1 GBG62502.1 - 2.1e-07 31.2 0.0 3.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62502.1 - 0.015 15.3 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG62502.1 - 0.71 8.0 8.6 0.89 7.7 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG62502.1 - 0.92 8.9 8.2 1.2 8.5 8.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG62502.1 - 1.2 7.3 5.7 1.5 7.0 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 GBG62503.1 - 1.6 7.8 9.7 2.6 7.1 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paf1 PF03985.13 GBG62503.1 - 3.9 6.4 9.9 5.5 5.9 9.9 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 GBG62503.1 - 4.1 5.6 6.4 5.6 5.1 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG62503.1 - 5.5 5.1 8.9 7.6 4.6 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family Retrotrans_gag PF03732.17 GBG62504.1 - 0.00032 20.9 3.6 0.00042 20.5 0.1 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG62505.1 - 1.3e-29 103.3 0.1 2e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62505.1 - 1.5e-14 53.9 0.1 5.1e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62505.1 - 2.2e-14 53.3 0.8 7.9e-14 51.5 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG62505.1 - 7e-12 45.1 0.0 1.6e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG62505.1 - 1.3e-11 44.7 0.0 3.3e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG62505.1 - 0.00092 19.4 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG62505.1 - 0.0033 17.7 0.0 0.0091 16.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PRIMA1 PF16101.5 GBG62505.1 - 0.016 15.3 7.1 0.67 10.0 0.2 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Dimer_Tnp_hAT PF05699.14 GBG62506.1 - 4.1e-05 23.3 0.2 9.3e-05 22.2 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG62506.1 - 4.9 7.4 10.7 0.074 13.0 2.7 2.5 2 0 0 2 2 2 0 AT hook motif bZIP_1 PF00170.21 GBG62507.1 - 2.5e-18 65.9 15.8 4e-18 65.3 15.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor MFMR PF07777.11 GBG62507.1 - 2.2e-14 53.7 12.3 6e-14 52.3 12.3 1.8 1 0 0 1 1 1 1 G-box binding protein MFMR bZIP_2 PF07716.15 GBG62507.1 - 1.1e-08 35.0 11.5 1.1e-08 35.0 11.5 2.2 1 1 1 2 2 2 1 Basic region leucine zipper KASH_CCD PF14662.6 GBG62507.1 - 0.0002 21.2 6.4 0.0003 20.7 6.4 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 GBG62507.1 - 0.013 14.7 3.9 0.019 14.2 3.9 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_Maf PF03131.17 GBG62507.1 - 0.33 11.5 12.9 0.6 10.7 12.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4407 PF14362.6 GBG62507.1 - 0.97 8.7 4.5 1.4 8.2 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 GBG62507.1 - 1.3 9.5 9.0 0.083 13.3 3.1 1.9 1 1 1 2 2 2 0 Cell division protein ZapB ADIP PF11559.8 GBG62507.1 - 2.2 8.4 12.0 3.6 7.7 12.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RVT_1 PF00078.27 GBG62508.1 - 7.4e-27 94.3 0.2 1.2e-26 93.7 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62508.1 - 2.1e-25 88.6 0.0 5.1e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62508.1 - 1.4e-24 86.4 0.0 3.2e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62508.1 - 2.5e-19 69.1 1.1 5.7e-19 68.0 0.6 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG62508.1 - 1.5e-08 34.8 0.0 4.7e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG62508.1 - 5.8e-07 30.0 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62508.1 - 6.6e-07 29.9 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG62508.1 - 2.3e-05 24.2 0.0 4.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62508.1 - 3.8e-05 23.5 0.0 6.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG62508.1 - 0.07 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG62509.1 - 4.9e-05 23.5 0.2 0.00014 22.0 0.1 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein Senescence_reg PF04520.13 GBG62509.1 - 0.0079 17.1 1.5 0.016 16.1 1.0 1.8 2 0 0 2 2 2 1 Senescence regulator SGIII PF15467.6 GBG62510.1 - 0.078 12.2 3.2 0.12 11.6 3.2 1.3 1 0 0 1 1 1 0 Secretogranin-3 UPF0220 PF05255.11 GBG62511.1 - 2.7e-25 88.8 0.4 3.2e-25 88.6 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1218 PF06749.12 GBG62511.1 - 0.0022 18.5 0.1 0.0034 17.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1218) ABC2_membrane_3 PF12698.7 GBG62511.1 - 0.12 11.5 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein TFIIA PF03153.13 GBG62513.1 - 0.062 13.3 16.8 0.11 12.5 16.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 GBG62513.1 - 3.1 5.9 26.6 4.9 5.2 26.6 1.2 1 0 0 1 1 1 0 Nop14-like family DUF659 PF04937.15 GBG62514.1 - 4.4e-20 72.1 0.0 6.2e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Nop14 PF04147.12 GBG62515.1 - 0.22 9.7 39.5 0.0065 14.8 33.3 1.5 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 GBG62515.1 - 0.23 10.8 33.3 0.65 9.4 33.3 1.7 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG62515.1 - 3 6.5 11.3 5.3 5.7 11.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MDM1 PF15501.6 GBG62516.1 - 0.091 11.9 24.1 0.095 11.8 24.1 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Spore_coat_CotO PF14153.6 GBG62516.1 - 0.66 9.9 29.8 0.81 9.6 29.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Zip PF02535.22 GBG62516.1 - 1 8.5 17.8 1.2 8.3 17.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 GBG62516.1 - 1 7.7 7.5 1.3 7.3 7.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BORG_CEP PF14957.6 GBG62516.1 - 1.3 10.1 12.3 1.9 9.6 12.3 1.4 1 0 0 1 1 1 0 Cdc42 effector DUF4045 PF13254.6 GBG62516.1 - 1.6 8.3 22.7 1.8 8.1 22.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 GBG62516.1 - 1.7 7.6 21.1 1.9 7.4 21.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 GBG62516.1 - 4.1 6.1 17.0 4.5 6.0 17.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIF_alpha PF05793.12 GBG62516.1 - 4.5 5.7 43.2 6.4 5.2 43.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Neur_chan_memb PF02932.16 GBG62516.1 - 5.2 7.1 12.4 5.8 6.9 12.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 GBG62516.1 - 5.4 5.7 22.0 5.7 5.6 22.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5427 PF10310.9 GBG62516.1 - 8.8 5.2 26.9 10 5.0 26.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SelP_N PF04592.14 GBG62516.1 - 9 5.6 17.4 12 5.3 17.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Endostatin PF06482.11 GBG62516.1 - 9 5.7 11.0 9.7 5.6 11.0 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Cpn60_TCP1 PF00118.24 GBG62517.1 - 8.7e-92 308.3 14.3 1.4e-91 307.6 14.3 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RVT_1 PF00078.27 GBG62517.1 - 3.5e-33 115.0 0.0 7e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3023 PF11224.8 GBG62517.1 - 0.08 12.8 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) Synaptobrevin PF00957.21 GBG62518.1 - 1.5e-28 98.4 0.1 2.3e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GBG62518.1 - 4e-25 87.7 0.0 5.6e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain TRIQK PF15168.6 GBG62518.1 - 0.038 13.9 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family GCV_T PF01571.21 GBG62519.1 - 3.9e-34 118.2 0.0 6.2e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain RT_RNaseH_2 PF17919.1 GBG62519.1 - 6.6e-25 87.1 0.0 2.3e-24 85.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62519.1 - 1e-15 57.9 0.0 2.9e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62519.1 - 2e-08 34.0 0.2 0.0017 17.9 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG62519.1 - 5.8e-06 26.9 0.0 1.7e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62519.1 - 1.7e-05 25.3 0.0 5.4e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62519.1 - 2.1e-05 24.3 0.0 9.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62519.1 - 0.00094 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Vps16_N PF04841.13 GBG62519.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region HIP1_clath_bdg PF16515.5 GBG62520.1 - 0.0074 16.9 7.6 0.0074 16.9 7.6 3.4 3 1 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 BLOC1_2 PF10046.9 GBG62520.1 - 0.013 15.8 2.4 0.013 15.8 2.4 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3006 PF11213.8 GBG62520.1 - 0.11 12.7 1.7 0.36 11.1 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) FliD_N PF02465.18 GBG62520.1 - 0.12 13.0 6.2 0.12 13.1 2.3 2.7 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FKS1_dom1 PF14288.6 GBG62520.1 - 0.17 12.2 2.3 1.4 9.3 2.0 2.5 1 1 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 ERM PF00769.19 GBG62520.1 - 0.25 11.1 25.2 0.41 10.4 24.9 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family NPV_P10 PF05531.12 GBG62520.1 - 2.2 8.8 7.4 3.6 8.1 0.1 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GBG62520.1 - 4 6.7 16.3 4.9 6.4 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Histone_HNS PF00816.21 GBG62520.1 - 4.2 8.3 11.6 11 7.0 0.7 2.4 2 0 0 2 2 2 0 H-NS histone family SPOUT_MTase PF02590.17 GBG62520.1 - 4.8 7.1 10.4 10 6.0 2.4 2.6 2 1 0 2 2 2 0 Predicted SPOUT methyltransferase DUF1664 PF07889.12 GBG62520.1 - 6.9 6.7 7.8 6.4 6.8 1.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Ax_dynein_light PF10211.9 GBG62520.1 - 9.8 6.1 17.8 3.7 7.5 4.6 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain PAP_fibrillin PF04755.12 GBG62521.1 - 8.5e-29 100.9 0.0 1.2e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin TFIIB PF00382.19 GBG62522.1 - 6e-28 96.7 3.8 3.4e-15 55.8 0.0 3.0 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 GBG62522.1 - 2.6e-24 85.5 2.6 2.6e-24 85.5 2.6 4.5 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 GBG62522.1 - 4.4e-06 26.1 2.2 1.9e-05 24.1 2.2 2.2 1 0 0 1 1 1 1 TFIIB zinc-binding DUF4589 PF15252.6 GBG62522.1 - 0.028 14.5 0.8 0.028 14.5 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) CENP-F_C_Rb_bdg PF10490.9 GBG62522.1 - 0.036 13.5 2.5 0.12 11.8 2.5 1.9 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Cyclin_N PF00134.23 GBG62522.1 - 0.039 13.7 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Cyclin, N-terminal domain RVT_1 PF00078.27 GBG62524.1 - 1.1e-27 97.0 0.1 1.8e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62524.1 - 1.4e-26 92.4 0.0 4.3e-26 90.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62524.1 - 7.8e-22 77.6 0.0 2.2e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG62524.1 - 6.7e-05 23.4 0.0 0.00015 22.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62524.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62524.1 - 0.00029 21.4 0.0 0.00061 20.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62524.1 - 0.00087 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG62524.1 - 0.032 14.1 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG62525.1 - 6.5e-28 97.7 0.1 1e-27 97.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62525.1 - 1.1e-26 92.8 0.0 2.7e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62525.1 - 6.5e-22 77.8 0.0 1.4e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG62525.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Band_7 PF01145.25 GBG62526.1 - 1.1e-17 64.6 0.0 1.1e-17 64.6 0.0 2.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family Draxin PF15550.6 GBG62526.1 - 3.6 7.4 7.4 5.3 6.8 7.4 1.2 1 0 0 1 1 1 0 Draxin RNA_polI_A34 PF08208.11 GBG62527.1 - 0.0034 17.5 14.5 0.0044 17.1 14.5 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.9 GBG62527.1 - 0.017 14.8 23.5 0.028 14.0 23.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Eapp_C PF10238.9 GBG62527.1 - 0.018 15.1 3.9 0.025 14.7 3.9 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein RR_TM4-6 PF06459.12 GBG62527.1 - 0.037 13.8 3.4 0.042 13.7 3.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 GBG62527.1 - 0.072 13.5 3.0 0.09 13.2 3.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RSB_motif PF16294.5 GBG62527.1 - 0.12 12.6 20.4 0.17 12.2 20.4 1.2 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif FAM199X PF15814.5 GBG62527.1 - 0.31 10.0 9.2 0.37 9.8 9.2 1.1 1 0 0 1 1 1 0 Protein family FAM199X Atg14 PF10186.9 GBG62527.1 - 0.32 10.1 8.9 0.35 9.9 8.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ureide_permease PF07168.11 GBG62527.1 - 0.32 9.7 0.6 0.41 9.3 0.6 1.1 1 0 0 1 1 1 0 Ureide permease Connexin PF00029.19 GBG62527.1 - 0.44 10.3 7.3 0.57 9.9 7.3 1.1 1 0 0 1 1 1 0 Connexin DUF2828 PF11443.8 GBG62527.1 - 0.66 8.0 10.1 0.82 7.7 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EOS1 PF12326.8 GBG62527.1 - 0.96 9.4 3.4 1.2 9.0 3.4 1.2 1 0 0 1 1 1 0 N-glycosylation protein Presenilin PF01080.17 GBG62527.1 - 1.2 7.9 3.6 1.3 7.7 3.6 1.1 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.19 GBG62527.1 - 1.2 7.9 4.2 1.6 7.6 4.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein IHO1 PF15771.5 GBG62527.1 - 1.8 7.2 15.0 2.3 6.9 15.0 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 DUF1943 PF09172.11 GBG62527.1 - 3.3 6.8 5.7 4 6.6 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) YqfQ PF14181.6 GBG62527.1 - 5.2 7.2 9.0 8.4 6.6 9.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein AF-4 PF05110.13 GBG62527.1 - 7 4.6 16.1 8.6 4.3 16.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_60s PF00428.19 GBG62528.1 - 3.3e-10 40.4 1.2 3.6e-10 40.3 0.4 1.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein Band_7 PF01145.25 GBG62530.1 - 1.7e-06 28.2 0.9 1.7e-06 28.2 0.9 2.3 2 1 0 2 2 2 1 SPFH domain / Band 7 family Peptidase_M14 PF00246.24 GBG62531.1 - 7.3e-50 170.4 0.3 1.7e-31 110.1 0.0 2.1 1 1 1 2 2 2 2 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 GBG62531.1 - 7.1e-09 35.8 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain PEGA PF08308.11 GBG62531.1 - 3.4e-07 30.1 0.0 6.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 PEGA domain CarbopepD_reg_2 PF13715.6 GBG62531.1 - 7.9e-07 29.0 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 GBG62531.1 - 0.0001 21.5 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 GBG62531.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) DUF2457 PF10446.9 GBG62532.1 - 0.0037 16.5 25.4 0.0044 16.2 25.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.12 GBG62532.1 - 0.017 13.3 23.1 0.018 13.3 23.1 1.0 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.11 GBG62532.1 - 0.048 13.4 24.3 0.06 13.0 24.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SDA1 PF05285.12 GBG62532.1 - 0.096 12.1 26.4 0.11 11.8 26.4 1.0 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 GBG62532.1 - 0.16 12.1 19.2 0.19 11.8 19.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG62532.1 - 0.22 10.9 21.7 0.24 10.7 21.7 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 GBG62532.1 - 0.27 9.7 19.5 0.29 9.5 19.5 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 GBG62532.1 - 0.49 8.9 22.5 0.48 9.0 22.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GBG62532.1 - 2.3 6.4 19.1 2.6 6.2 19.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 GBG62532.1 - 2.5 7.1 18.4 2.7 7.0 18.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PTPRCAP PF15713.5 GBG62532.1 - 6 7.1 23.0 7.7 6.8 23.0 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4746 PF15928.5 GBG62532.1 - 6.7 6.0 13.6 8.3 5.7 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ThiF PF00899.21 GBG62533.1 - 8.5e-68 228.3 0.0 1.3e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 GBG62533.1 - 5.7e-24 84.1 0.1 8.9e-24 83.5 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain LAP1C PF05609.12 GBG62533.1 - 5.6 6.0 13.4 7.8 5.5 13.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4770 PF15994.5 GBG62533.1 - 8.3 6.6 10.4 24 5.1 10.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Retrotrans_gag PF03732.17 GBG62535.1 - 0.0093 16.2 0.4 0.045 14.0 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein ADP_ribosyl_GH PF03747.14 GBG62535.1 - 0.2 11.4 0.4 0.47 10.1 0.2 1.8 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase Peptidase_C12 PF01088.21 GBG62536.1 - 5.2e-59 199.5 0.0 6e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HpaB PF03241.13 GBG62536.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal GST_N_3 PF13417.6 GBG62537.1 - 8.3e-18 64.6 0.0 1.7e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG62537.1 - 2e-14 53.6 0.0 4.2e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GBG62537.1 - 3.6e-14 52.9 0.0 5.9e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GBG62537.1 - 2.7e-05 24.3 0.0 7.5e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 GBG62537.1 - 6.4e-05 22.9 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GBG62537.1 - 0.0001 22.4 0.0 0.00026 21.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GBG62537.1 - 0.0071 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CaATP_NAI PF12515.8 GBG62537.1 - 0.048 13.3 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain GIY-YIG PF01541.24 GBG62539.1 - 1.6e-12 47.5 0.0 3.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain SNO PF01174.19 GBG62540.1 - 5.4e-49 166.6 0.0 3.7e-42 144.3 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 GBG62540.1 - 1.2e-09 38.1 0.1 2.2e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 GBG62540.1 - 7e-05 22.7 0.0 0.031 14.0 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 GBG62540.1 - 0.00029 20.5 0.1 0.00051 19.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 GBG62540.1 - 0.0011 18.8 0.1 0.0028 17.5 0.1 1.6 2 0 0 2 2 2 1 DJ-1/PfpI family gag-asp_proteas PF13975.6 GBG62542.1 - 5.6e-06 26.8 0.1 1.2e-05 25.8 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62542.1 - 0.00054 20.6 0.1 0.0013 19.3 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG62542.1 - 0.0022 17.7 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62542.1 - 0.016 15.0 0.2 0.024 14.4 0.2 1.2 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG62542.1 - 0.059 13.0 0.3 0.13 12.0 0.3 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG62542.1 - 0.071 13.2 1.9 0.13 12.4 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle cNMP_binding PF00027.29 GBG62542.1 - 0.1 12.7 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain gag-asp_proteas PF13975.6 GBG62544.1 - 0.011 16.3 1.1 0.024 15.2 0.2 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62544.1 - 0.011 16.3 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Paf1 PF03985.13 GBG62544.1 - 0.015 14.3 1.8 0.021 13.9 1.8 1.1 1 0 0 1 1 1 0 Paf1 Asp_protease PF09668.10 GBG62544.1 - 0.047 13.5 0.2 0.11 12.3 0.2 1.6 2 0 0 2 2 2 0 Aspartyl protease CMAS PF02353.20 GBG62545.1 - 3.5e-81 272.5 0.0 6.9e-81 271.5 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Amino_oxidase PF01593.24 GBG62545.1 - 7.7e-19 68.3 0.2 3.2e-18 66.3 0.0 1.9 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG62545.1 - 1.7e-17 63.4 0.1 5.1e-17 61.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_25 PF13649.6 GBG62545.1 - 2.2e-13 50.7 0.0 5.5e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG62545.1 - 1.9e-11 44.4 0.0 5.3e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG62545.1 - 1.5e-08 35.3 0.0 3.4e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG62545.1 - 1.7e-08 34.5 0.0 4.6e-08 33.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG62545.1 - 3.1e-07 30.3 0.0 5.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.24 GBG62545.1 - 8.5e-07 28.9 0.1 2.6e-06 27.3 0.0 1.8 3 0 0 3 3 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG62545.1 - 1.4e-05 24.4 0.3 2e-05 23.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GBG62545.1 - 9.7e-05 21.9 0.3 0.00015 21.3 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GBG62545.1 - 0.00021 20.6 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GBG62545.1 - 0.00063 19.1 0.5 0.0017 17.7 0.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG62545.1 - 0.0016 17.3 0.3 0.0032 16.2 0.3 1.5 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 GBG62545.1 - 0.0019 17.3 1.1 0.0028 16.8 1.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FMO-like PF00743.19 GBG62545.1 - 0.013 14.0 0.1 0.022 13.2 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 GBG62545.1 - 0.019 15.5 0.8 0.34 11.5 0.4 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MTS PF05175.14 GBG62545.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain FAD_binding_3 PF01494.19 GBG62545.1 - 0.026 13.8 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 GBG62545.1 - 0.028 14.4 0.2 0.067 13.2 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 GBG62545.1 - 0.03 13.6 0.3 0.06 12.6 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GBG62545.1 - 0.033 14.1 0.4 0.15 11.9 0.3 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCMT PF01135.19 GBG62545.1 - 0.052 13.3 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 GBG62545.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pyr_redox_3 PF13738.6 GBG62545.1 - 0.12 11.6 0.1 0.26 10.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_3 PF01596.17 GBG62545.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase NB-ARC PF00931.22 GBG62546.1 - 6e-38 130.5 0.0 9.7e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain LRR_8 PF13855.6 GBG62546.1 - 1.6e-23 82.2 22.5 0.00011 21.9 1.3 9.1 4 3 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 GBG62546.1 - 2.2e-21 75.6 22.5 0.0013 19.1 0.5 10.2 5 2 5 11 11 11 9 Leucine Rich repeats (2 copies) AAA_16 PF13191.6 GBG62546.1 - 7.6e-05 23.2 0.0 0.0004 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GBG62546.1 - 0.05 13.5 0.2 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 GBG62546.1 - 0.061 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GBG62546.1 - 0.076 13.4 0.0 0.32 11.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG62546.1 - 0.079 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF1319 PF07028.11 GBG62546.1 - 0.14 12.4 0.5 1.8 8.8 0.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) DUF1664 PF07889.12 GBG62546.1 - 0.36 10.9 2.5 15 5.6 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DisA-linker PF10635.9 GBG62546.1 - 3.9 7.2 5.3 9.1 6.0 0.1 2.8 3 0 0 3 3 3 0 DisA bacterial checkpoint controller linker region LRR_1 PF00560.33 GBG62546.1 - 6.1 7.8 20.3 1.1e+02 3.9 0.0 9.6 11 0 0 11 11 10 0 Leucine Rich Repeat RVT_1 PF00078.27 GBG62547.1 - 1.6e-26 93.2 0.0 2.8e-25 89.2 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S49 PF01343.18 GBG62551.1 - 1.4e-18 67.4 0.6 2.1e-18 66.8 0.6 1.2 1 0 0 1 1 1 1 Peptidase family S49 ECH_1 PF00378.20 GBG62551.1 - 0.0094 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PapD-like PF14874.6 GBG62552.1 - 0.089 13.0 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Flagellar-associated PapD-like UcrQ PF02939.16 GBG62552.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.2 3 0 0 3 3 3 0 UcrQ family SR-25 PF10500.9 GBG62553.1 - 2.8 7.5 19.3 0.81 9.2 14.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HEAT_2 PF13646.6 GBG62554.1 - 9.2e-05 22.8 16.6 2.4 8.6 0.4 5.8 5 1 0 5 5 5 3 HEAT repeats Adaptin_N PF01602.20 GBG62554.1 - 0.0011 17.6 1.2 0.1 11.1 0.1 2.6 2 0 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 GBG62554.1 - 0.0032 17.6 21.6 3.2 8.2 0.2 8.2 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 GBG62554.1 - 0.0035 17.4 0.1 0.95 9.5 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GBG62554.1 - 0.76 9.9 6.2 1 9.5 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GBG62554.1 - 3.1 8.4 19.5 8.2 7.0 0.1 7.0 5 2 2 7 7 7 0 HEAT-like repeat HEAT_2 PF13646.6 GBG62555.1 - 8.8e-05 22.8 16.6 2.4 8.6 0.4 5.8 5 1 0 5 5 5 3 HEAT repeats Adaptin_N PF01602.20 GBG62555.1 - 0.0011 17.7 1.2 0.1 11.1 0.1 2.6 2 0 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 GBG62555.1 - 0.0031 17.6 21.6 3.2 8.3 0.2 8.2 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 GBG62555.1 - 0.0034 17.4 0.1 0.94 9.5 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GBG62555.1 - 0.73 10.0 6.2 1 9.5 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GBG62555.1 - 2.9 8.5 19.5 8.1 7.1 0.1 7.0 5 2 2 7 7 7 0 HEAT-like repeat HEAT_2 PF13646.6 GBG62556.1 - 8.3e-05 22.9 16.6 2.3 8.6 0.4 5.8 5 1 0 5 5 5 3 HEAT repeats Adaptin_N PF01602.20 GBG62556.1 - 0.001 17.7 1.2 0.1 11.1 0.1 2.6 2 0 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 GBG62556.1 - 0.003 17.7 21.6 3.2 8.3 0.2 8.2 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 GBG62556.1 - 0.0033 17.5 0.1 0.93 9.5 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GBG62556.1 - 0.72 10.0 6.2 1 9.5 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GBG62556.1 - 3.1 8.4 19.6 8.1 7.1 0.1 7.0 5 2 2 7 7 7 0 HEAT-like repeat DUF3824 PF12868.7 GBG62557.1 - 0.37 11.4 6.5 0.59 10.8 6.5 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Gly_rich PF12810.7 GBG62557.1 - 0.78 9.6 26.5 0.87 9.5 26.5 1.1 1 0 0 1 1 1 0 Glycine rich protein DUF3915 PF13054.6 GBG62557.1 - 1.9 8.5 8.6 2.7 8.0 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Fer2 PF00111.27 GBG62558.1 - 3.8e-20 71.6 0.8 5.4e-20 71.1 0.8 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Synaptobrevin PF00957.21 GBG62559.1 - 1.7e-23 82.2 5.7 2.4e-23 81.7 5.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GBG62559.1 - 2.2e-17 62.9 0.0 3.3e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain T2SSF PF00482.23 GBG62559.1 - 0.3 11.1 1.2 1.1 9.2 1.2 1.9 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Uteroglobin PF01099.17 GBG62559.1 - 0.54 10.6 0.0 0.54 10.6 0.0 2.4 3 1 1 4 4 4 0 Uteroglobin family Sigma_reg_N PF13800.6 GBG62559.1 - 1.2 9.5 5.9 2.5 8.5 5.9 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF659 PF04937.15 GBG62560.1 - 2.6e-18 66.3 0.0 4e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zinc_ribbon_4 PF13717.6 GBG62560.1 - 0.0024 17.8 0.3 3.5 7.6 0.0 2.5 2 0 0 2 2 2 2 zinc-ribbon domain DUF3449 PF11931.8 GBG62560.1 - 0.007 16.2 0.1 4.6 7.0 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) zf-Sec23_Sec24 PF04810.15 GBG62560.1 - 0.14 12.2 0.3 28 4.9 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger RETICULATA-like PF11891.8 GBG62563.1 - 3.1e-56 190.0 0.0 5.5e-56 189.2 0.0 1.4 1 0 0 1 1 1 1 Protein RETICULATA-related COX6B PF02297.17 GBG62564.1 - 0.05 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb D5_N PF08706.11 GBG62564.1 - 0.14 12.4 1.6 0.26 11.5 0.2 2.0 2 0 0 2 2 2 0 D5 N terminal like RVT_1 PF00078.27 GBG62565.1 - 3.6e-29 101.9 0.1 5.7e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62565.1 - 1.2e-26 92.7 0.0 2.6e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62565.1 - 1.4e-25 89.6 0.0 3e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62565.1 - 8.1e-19 67.5 0.8 1.7e-18 66.5 0.8 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG62565.1 - 0.017 15.3 0.1 0.047 13.9 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG62566.1 - 6.2e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62566.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG62568.1 - 3.9e-31 107.9 0.0 5.9e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62568.1 - 8.4e-13 48.4 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG62568.1 - 9.4e-05 22.1 3.6 0.0092 15.6 0.0 2.8 3 1 0 3 3 3 2 Transposase DDE domain DUF2694 PF10904.8 GBG62568.1 - 0.12 12.4 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) Myb_DNA-binding PF00249.31 GBG62569.1 - 6e-33 112.8 2.3 2e-15 56.7 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG62569.1 - 4.2e-20 71.7 1.3 2.4e-14 53.3 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GBG62569.1 - 0.0086 16.0 0.0 0.037 13.9 0.0 2.0 1 1 1 2 2 2 1 Myb DNA-binding like DUF3194 PF11419.8 GBG62570.1 - 0.13 12.7 4.5 0.57 10.6 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3194) zf-CCHC PF00098.23 GBG62571.1 - 0.00073 19.5 4.9 0.0013 18.7 4.9 1.4 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH PF17917.1 GBG62572.1 - 9.9e-26 90.1 0.0 2.8e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62572.1 - 8e-25 86.8 0.0 1.9e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62572.1 - 4.3e-22 78.7 0.1 3.3e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62572.1 - 5.6e-17 61.6 0.5 1.1e-16 60.6 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG62572.1 - 0.0039 17.4 1.4 0.017 15.4 0.4 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG62572.1 - 0.0052 17.0 0.1 0.028 14.6 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain PPR PF01535.20 GBG62573.1 - 1.3e-55 181.8 22.2 1.9e-06 27.7 0.0 10.7 11 0 0 11 11 10 9 PPR repeat PPR_2 PF13041.6 GBG62573.1 - 1.2e-54 182.2 3.9 4.8e-11 42.7 0.0 7.3 3 3 3 7 7 7 7 PPR repeat family PPR_1 PF12854.7 GBG62573.1 - 4.7e-53 176.6 9.7 4.5e-07 29.4 0.0 10.4 10 0 0 10 10 10 9 PPR repeat PPR_3 PF13812.6 GBG62573.1 - 1.1e-38 131.1 0.0 2.2e-08 34.1 0.0 5.4 4 1 0 5 5 5 5 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG62573.1 - 3.9e-18 65.6 0.0 9.3e-05 21.9 0.0 3.3 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP DUF1884 PF08967.10 GBG62573.1 - 4.1e-05 23.7 0.0 2.9 8.2 0.0 4.4 3 1 1 4 4 4 1 Domain of unknown function (DUF1884) Smr PF01713.21 GBG62573.1 - 5.8e-05 23.4 0.0 0.0002 21.7 0.0 2.0 1 0 0 1 1 1 1 Smr domain TPR_14 PF13428.6 GBG62573.1 - 8.5e-05 23.1 4.2 0.86 10.6 0.1 5.6 5 2 2 7 7 4 1 Tetratricopeptide repeat Clathrin PF00637.20 GBG62573.1 - 0.00049 20.0 0.0 0.21 11.5 0.0 3.9 3 2 2 5 5 5 1 Region in Clathrin and VPS Exog_C PF18026.1 GBG62573.1 - 0.00064 19.7 0.0 33 4.7 0.0 4.1 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain TPR_7 PF13176.6 GBG62573.1 - 0.0038 17.2 0.1 9 6.6 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG62573.1 - 0.023 15.2 2.5 2.6 8.6 0.5 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat SPOB_a PF14689.6 GBG62573.1 - 0.045 13.4 0.1 23 4.8 0.0 4.4 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF3368 PF11848.8 GBG62573.1 - 0.11 12.3 0.0 2e+02 1.8 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF3368) Mad3_BUB1_I PF08311.12 GBG62573.1 - 0.19 11.7 0.1 0.58 10.2 0.1 1.8 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 GBG62573.1 - 0.78 10.1 3.3 54 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 GBG62574.1 - 5.9e-12 45.5 0.0 1.7e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62574.1 - 2.6e-06 27.1 0.1 0.045 13.3 0.1 3.0 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG62574.1 - 4.9e-06 27.1 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62574.1 - 1.6e-05 25.4 0.0 4.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62574.1 - 0.00034 20.4 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG62574.1 - 0.00039 20.7 0.4 0.0027 18.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG62574.1 - 0.00092 19.4 11.1 0.023 14.9 0.0 4.7 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG62574.1 - 0.0013 18.5 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease NikR_C PF08753.11 GBG62574.1 - 0.22 11.7 1.9 0.76 10.0 1.9 2.0 1 0 0 1 1 1 0 NikR C terminal nickel binding domain Syntaxin-6_N PF09177.11 GBG62574.1 - 6.7 7.3 6.6 9.8 6.8 1.9 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal rve PF00665.26 GBG62575.1 - 5.5e-10 39.5 0.0 1.7e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG62575.1 - 0.049 13.5 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2497 PF10691.9 GBG62575.1 - 0.17 12.3 0.4 5 7.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) EMP24_GP25L PF01105.24 GBG62576.1 - 1.4e-30 106.6 0.1 2e-30 106.1 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PPR PF01535.20 GBG62576.1 - 3.7e-09 36.2 0.1 1.2e-06 28.4 0.0 3.0 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 GBG62576.1 - 7.6e-09 35.6 0.1 2.4e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family PPR_1 PF12854.7 GBG62576.1 - 1.2e-06 28.1 0.3 0.00015 21.3 0.1 3.2 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 GBG62576.1 - 0.0008 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.20 GBG62577.1 - 1.8e-09 37.2 0.0 8.1e-07 28.9 0.0 3.0 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 GBG62577.1 - 4.3e-09 36.4 0.1 1.7e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family PPR_1 PF12854.7 GBG62577.1 - 5.1e-07 29.3 0.3 0.00011 21.8 0.1 3.2 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 GBG62577.1 - 0.00057 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG62577.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Bap31 PF05529.12 GBG62578.1 - 6.5e-07 29.3 3.1 2.4e-06 27.4 3.1 1.9 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region OmpH PF03938.14 GBG62578.1 - 0.0024 18.2 5.0 0.0036 17.7 5.0 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) BRE1 PF08647.11 GBG62578.1 - 0.0052 16.8 9.2 0.012 15.7 9.0 1.6 1 1 0 1 1 1 1 BRE1 E3 ubiquitin ligase AAA_13 PF13166.6 GBG62578.1 - 0.016 13.9 1.4 0.021 13.5 1.4 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.7 GBG62578.1 - 0.067 13.3 8.9 0.12 12.5 8.9 1.4 1 0 0 1 1 1 0 Tropomyosin like Spc7 PF08317.11 GBG62578.1 - 0.1 11.4 7.0 0.14 11.0 7.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DHR10 PF18595.1 GBG62578.1 - 0.13 12.4 10.7 0.21 11.7 10.7 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF724 PF05266.14 GBG62578.1 - 0.16 11.8 4.8 0.25 11.1 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) EF_assoc_1 PF08355.12 GBG62578.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 EF hand associated APG6_N PF17675.1 GBG62578.1 - 0.22 12.1 9.0 0.38 11.3 9.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 GBG62578.1 - 0.26 10.3 4.1 0.42 9.7 4.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin-6_N PF09177.11 GBG62578.1 - 0.31 11.6 3.0 0.51 10.9 3.0 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TMPIT PF07851.13 GBG62578.1 - 0.81 8.9 3.4 1.2 8.3 3.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Ly49 PF08391.10 GBG62578.1 - 0.93 9.9 8.4 0.054 13.8 2.1 2.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region FAM76 PF16046.5 GBG62578.1 - 1.5 8.1 6.2 1.8 7.9 6.2 1.3 1 1 0 1 1 1 0 FAM76 protein Prefoldin_2 PF01920.20 GBG62578.1 - 1.7 8.7 10.9 0.13 12.2 3.0 2.1 1 1 1 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.21 GBG62578.1 - 2.3 8.4 12.0 0.39 10.8 1.9 2.5 1 1 1 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.11 GBG62578.1 - 6.5 7.2 7.5 2.9 8.3 1.7 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF659 PF04937.15 GBG62579.1 - 1.2e-23 83.6 0.0 2.4e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG62580.1 - 2.3e-30 105.8 0.0 3.4e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG62580.1 - 2.6e-10 40.0 0.0 6.5e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG62581.1 - 1.5e-25 90.0 0.0 3e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG62581.1 - 2.8e-05 24.7 0.0 7.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62581.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62581.1 - 0.00032 21.2 0.0 0.00087 19.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62581.1 - 0.00092 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG62581.1 - 0.18 12.1 10.2 0.19 12.0 0.0 5.1 5 0 0 5 5 5 0 Retrotransposon gag protein Syntaxin-6_N PF09177.11 GBG62581.1 - 4.1 8.0 6.5 4.5 7.9 1.7 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Reticulon PF02453.17 GBG62584.1 - 1.5e-10 41.3 0.3 1.9e-10 41.0 0.3 1.2 1 0 0 1 1 1 1 Reticulon Babuvirus_MP PF07234.11 GBG62584.1 - 0.078 13.1 0.1 0.079 13.1 0.1 1.2 1 0 0 1 1 1 0 Movement and RNA silencing protein TMEM131_like PF12371.8 GBG62586.1 - 2.1e-22 79.2 0.2 6.4e-18 64.8 0.0 4.2 5 0 0 5 5 5 2 Transmembrane protein 131-like ASH PF15780.5 GBG62586.1 - 3.1e-09 36.9 0.0 0.026 14.7 0.0 4.6 5 0 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 GBG62586.1 - 0.00018 21.4 0.0 0.024 14.7 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1573) Myb_DNA-bind_4 PF13837.6 GBG62588.1 - 0.00015 22.1 1.8 0.00027 21.2 1.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF5102 PF17104.5 GBG62590.1 - 0.98 9.4 8.7 0.36 10.8 5.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5102) RVT_1 PF00078.27 GBG62591.1 - 1.1e-25 90.4 0.0 1.7e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG62591.1 - 0.0095 14.3 15.1 0.014 13.7 15.1 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GBG62591.1 - 0.016 14.7 20.8 0.028 13.9 20.8 1.3 1 0 0 1 1 1 0 SDA1 DUF2052 PF09747.9 GBG62591.1 - 0.024 14.8 16.8 0.056 13.6 16.8 1.7 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RVP_2 PF08284.11 GBG62591.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease SAPS PF04499.15 GBG62591.1 - 0.19 10.5 4.6 0.29 9.9 4.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 GBG62591.1 - 0.22 11.1 10.8 0.43 10.1 10.8 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NPR3 PF03666.13 GBG62591.1 - 0.8 8.4 3.0 1.1 7.9 3.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GBG62591.1 - 1.8 7.3 10.8 2.8 6.6 10.8 1.2 1 0 0 1 1 1 0 Presenilin YL1 PF05764.13 GBG62591.1 - 3.4 7.7 30.0 0.44 10.6 25.7 1.6 2 0 0 2 2 2 0 YL1 nuclear protein BUD22 PF09073.10 GBG62591.1 - 5.2 6.3 24.6 9.3 5.5 24.6 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG62591.1 - 5.8 5.0 26.4 9 4.4 26.4 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG62591.1 - 5.9 6.6 16.6 13 5.5 16.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FliE PF02049.18 GBG62592.1 - 0.082 13.1 0.1 6.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE SDA1 PF05285.12 GBG62595.1 - 0.0091 15.5 21.5 0.011 15.2 21.5 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG62595.1 - 0.041 12.1 20.1 0.048 11.9 20.1 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG62595.1 - 0.11 11.3 3.5 0.12 11.2 3.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 GBG62595.1 - 0.14 10.4 14.8 0.18 10.1 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG62595.1 - 0.16 11.3 22.8 0.23 10.7 22.8 1.2 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG62595.1 - 0.29 10.6 11.1 0.39 10.2 11.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist YL1 PF05764.13 GBG62595.1 - 0.34 11.0 23.5 0.49 10.5 23.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Isy1 PF06246.12 GBG62595.1 - 1 8.8 12.8 1.5 8.3 12.8 1.1 1 0 0 1 1 1 0 Isy1-like splicing family Presenilin PF01080.17 GBG62595.1 - 1.3 7.7 10.6 2 7.1 10.6 1.2 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 GBG62595.1 - 7.7 5.5 11.7 10 5.1 11.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DDE_Tnp_4 PF13359.6 GBG62596.1 - 1.8e-25 89.4 0.0 4.8e-25 88.1 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62596.1 - 6.7e-14 52.0 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG62596.1 - 0.0047 16.6 0.2 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG62597.1 - 1.3e-28 98.9 0.0 1.7e-27 95.4 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62597.1 - 9.8e-28 97.2 0.1 1.8e-27 96.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62597.1 - 1e-25 90.0 0.0 4.5e-25 88.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62597.1 - 1.2e-17 63.7 0.1 3.2e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG62597.1 - 1.1e-07 32.4 0.0 2.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62597.1 - 1.5e-06 28.6 0.0 4e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62597.1 - 6e-05 22.8 0.0 0.00016 21.5 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62597.1 - 0.00053 19.8 0.0 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG62597.1 - 0.00083 19.6 0.7 0.0064 16.7 0.0 2.9 3 1 0 3 3 3 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG62597.1 - 9.5 5.5 9.0 16 4.7 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RT_RNaseH PF17917.1 GBG62598.1 - 1.1e-22 80.3 0.0 1.8e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62598.1 - 3.8e-22 78.2 0.0 6.6e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62598.1 - 1.8e-16 60.0 1.7 2.2e-16 59.7 0.5 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG62598.1 - 8.3e-06 26.0 0.0 2.6e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-TRAF_2 PF15965.5 GBG62599.1 - 6.1e-11 42.6 13.8 1.8e-07 31.5 2.1 3.1 2 1 1 3 3 3 2 TRAF-like zinc-finger zf-TRAF PF02176.18 GBG62599.1 - 1.3e-07 32.2 12.3 0.0004 21.0 2.5 3.4 3 1 0 3 3 2 2 TRAF-type zinc finger zf_UBZ PF18439.1 GBG62599.1 - 0.00031 20.3 1.4 0.06 12.9 0.1 2.6 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Sina PF03145.16 GBG62599.1 - 0.00033 20.7 1.2 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Seven in absentia protein family zf-C3HC4_2 PF13923.6 GBG62599.1 - 0.00039 20.2 9.1 0.00039 20.2 9.1 3.1 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG62599.1 - 0.00054 19.8 8.7 0.00054 19.8 8.7 2.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 GBG62599.1 - 0.00063 19.6 4.5 0.0031 17.4 4.5 2.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein YabA PF06156.13 GBG62599.1 - 0.00063 20.3 0.5 0.0013 19.4 0.5 1.4 1 0 0 1 1 1 1 Initiation control protein YabA ZapB PF06005.12 GBG62599.1 - 0.00081 19.8 3.6 0.0016 18.9 3.6 1.4 1 0 0 1 1 1 1 Cell division protein ZapB zf-RING_UBOX PF13445.6 GBG62599.1 - 0.0017 18.3 6.3 0.012 15.6 6.0 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 GBG62599.1 - 0.0023 18.1 5.6 0.0023 18.1 5.6 2.1 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-FPG_IleRS PF06827.14 GBG62599.1 - 0.0086 15.9 4.3 1.3 9.0 0.8 3.0 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS zf-RING_5 PF14634.6 GBG62599.1 - 0.032 14.2 7.9 0.032 14.2 7.9 2.6 2 1 1 3 3 2 0 zinc-RING finger domain zf-U11-48K PF05253.12 GBG62599.1 - 0.053 13.5 2.2 9.3 6.3 0.0 3.3 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger JIP_LZII PF16471.5 GBG62599.1 - 0.066 13.4 0.8 0.12 12.5 0.8 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II TSC22 PF01166.18 GBG62599.1 - 0.11 12.8 0.3 0.27 11.6 0.3 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 GBG62599.1 - 0.18 11.6 0.4 0.33 10.7 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Shugoshin_N PF07558.11 GBG62599.1 - 0.47 10.4 6.1 2.1 8.3 1.2 2.5 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region NRBF2 PF08961.10 GBG62599.1 - 0.79 9.3 2.4 1.2 8.7 2.4 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator zf_C2H2_10 PF18414.1 GBG62599.1 - 2.7 7.6 6.9 22 4.7 0.1 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger TerY_C PF15616.6 GBG62599.1 - 7.7 6.6 10.3 1.2 9.2 0.9 2.4 2 0 0 2 2 2 0 TerY-C metal binding domain 30K_MP_C_Ter PF11330.8 GBG62600.1 - 0.81 9.0 4.5 2.1 7.6 4.5 1.7 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins RVT_1 PF00078.27 GBG62602.1 - 1.3e-30 106.5 0.0 2.6e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62602.1 - 3.4e-26 91.2 0.0 7.7e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62602.1 - 1.9e-23 82.7 0.0 3.5e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62602.1 - 1.3e-19 70.0 0.2 2.5e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62602.1 - 3.3e-09 37.0 0.0 1.4e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG62602.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger APG17 PF04108.12 GBG62602.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Tudor-knot PF11717.8 GBG62602.1 - 0.17 11.8 0.0 0.49 10.3 0.0 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Methyltransf_29 PF03141.16 GBG62603.1 - 3.8e-202 672.4 0.0 4.4e-202 672.1 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 GBG62603.1 - 6e-12 46.1 0.0 1e-07 32.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GBG62603.1 - 3.6e-09 37.2 0.0 2.4e-05 25.0 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GBG62603.1 - 4.9e-07 29.7 0.0 0.02 14.7 0.0 3.0 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 GBG62603.1 - 3.3e-06 27.0 0.0 0.12 12.2 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GBG62603.1 - 0.0004 21.1 0.0 1.4 9.7 0.0 3.1 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_PK PF05891.12 GBG62603.1 - 0.051 13.1 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase DDE_Tnp_4 PF13359.6 GBG62604.1 - 6.7e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 GBG62604.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain RVT_1 PF00078.27 GBG62606.1 - 1.7e-30 106.2 0.0 2.8e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62606.1 - 2.5e-17 63.1 0.1 5.1e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62606.1 - 6.4e-14 51.8 0.1 1.5e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG62606.1 - 4.1e-10 39.6 0.0 1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG62606.1 - 1e-05 25.6 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG62607.1 - 4.6e-89 292.9 1.2 6e-33 112.9 0.0 4.1 4 0 0 4 4 4 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62607.1 - 3.1e-76 252.4 1.2 7.3e-30 103.4 0.1 3.5 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62607.1 - 2.5e-56 190.7 0.7 4.1e-28 98.4 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62607.1 - 7e-15 54.9 0.0 1.9e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG62607.1 - 6.5e-05 23.4 0.0 0.00019 21.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 GBG62607.1 - 0.0015 18.5 1.5 0.0045 16.9 1.5 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF2584 PF10763.9 GBG62607.1 - 0.018 15.2 0.1 49 4.2 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2584) DUF5095 PF17016.5 GBG62607.1 - 0.032 13.9 2.4 5.1 6.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) RVP_2 PF08284.11 GBG62607.1 - 0.045 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62607.1 - 0.1 13.3 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG62607.1 - 0.14 12.5 0.2 0.61 10.4 0.1 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein DUF1758 PF05585.12 GBG62607.1 - 0.18 11.5 0.1 0.41 10.4 0.1 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 GBG62608.1 - 3.7e-19 68.6 0.1 8.3e-19 67.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG62608.1 - 3.4e-17 62.6 0.1 7.6e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62608.1 - 3.9e-13 49.7 0.1 9.2e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG62608.1 - 1.2e-10 41.3 0.0 2.5e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG62608.1 - 0.0028 17.8 0.0 0.0085 16.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG62608.1 - 0.047 13.4 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG62610.1 - 1.2e-29 103.4 0.0 2.3e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62610.1 - 1.7e-16 60.1 0.1 3.9e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG62610.1 - 6.7e-10 39.2 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62610.1 - 7.9e-10 39.0 0.0 2.2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG62610.1 - 1.7e-06 27.8 0.0 3.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62610.1 - 7.7e-06 26.5 0.0 2.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62610.1 - 7.9e-05 23.1 0.0 0.00029 21.3 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG62610.1 - 0.00018 21.5 0.1 0.0004 20.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG62610.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RNA_pol_L_2 PF13656.6 GBG62612.1 - 0.058 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain CH PF00307.31 GBG62613.1 - 1.4e-74 247.2 0.7 1.7e-18 66.8 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GBG62613.1 - 5e-14 51.9 0.0 5.8e-05 22.8 0.0 4.0 4 0 0 4 4 4 3 CAMSAP CH domain CH_2 PF06294.11 GBG62613.1 - 3e-05 24.1 0.0 1.5 9.0 0.0 4.3 4 0 0 4 4 4 2 CH-like domain in sperm protein EF-hand_8 PF13833.6 GBG62613.1 - 0.089 12.7 0.3 0.2 11.5 0.3 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 GBG62613.1 - 0.26 11.8 0.7 0.6 10.6 0.7 1.6 1 0 0 1 1 1 0 EF-hand domain pair MPLKIP PF15502.6 GBG62614.1 - 2.2e-08 34.2 0.0 4.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 M-phase-specific PLK1-interacting protein Ribosomal_S26e PF01283.19 GBG62615.1 - 5.9e-52 174.7 7.6 6.9e-52 174.4 7.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 GBG62615.1 - 0.11 13.1 3.7 0.34 11.5 3.6 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Ribosomal_L37e PF01907.19 GBG62617.1 - 1.3e-27 95.7 9.9 2.4e-27 94.8 9.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DUF1258 PF06869.12 GBG62617.1 - 0.076 12.5 0.7 0.084 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) zf-RING_10 PF16685.5 GBG62617.1 - 0.078 13.1 1.7 0.1 12.7 1.7 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 Ribosomal_S14 PF00253.21 GBG62617.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e HypA PF01155.19 GBG62617.1 - 0.11 12.5 0.8 0.16 12.0 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 GBG62617.1 - 0.29 11.3 2.5 0.56 10.4 2.4 1.5 1 1 0 1 1 1 0 Zinc ribbon domain LRR_4 PF12799.7 GBG62618.1 - 1.1e-16 60.7 7.9 9.2e-06 25.9 1.3 3.5 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG62618.1 - 2e-12 46.7 13.2 2.2e-07 30.6 5.8 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 GBG62618.1 - 2e-08 33.9 0.1 2e-08 33.9 0.1 2.5 2 1 1 3 3 3 2 Leucine-rich repeat TPR_MLP1_2 PF07926.12 GBG62618.1 - 6e-05 23.1 9.8 6e-05 23.1 9.8 10.1 3 1 7 10 10 10 3 TPR/MLP1/MLP2-like protein LRR_6 PF13516.6 GBG62618.1 - 0.0099 15.9 16.0 6.7 7.0 0.1 5.1 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 GBG62618.1 - 0.22 12.2 9.8 62 4.7 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat RACo_C_ter PF14574.6 GBG62619.1 - 0.03 13.4 0.1 0.071 12.1 0.1 1.6 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain RVT_1 PF00078.27 GBG62620.1 - 1.3e-33 116.4 0.1 1.9e-33 115.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG62621.1 - 2.3e-07 30.6 0.2 5.1e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG62621.1 - 7.3e-06 25.8 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG62621.1 - 4.1e-05 24.0 0.0 0.00018 22.0 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62621.1 - 4.4e-05 24.0 0.0 0.00012 22.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG62621.1 - 0.0051 16.7 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HIP1_clath_bdg PF16515.5 GBG62621.1 - 0.013 16.1 3.8 0.013 16.1 3.8 4.0 5 1 0 5 5 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Retrotrans_gag PF03732.17 GBG62621.1 - 0.013 15.8 0.0 0.013 15.8 0.0 3.6 4 0 0 4 4 3 0 Retrotransposon gag protein SPARC_Ca_bdg PF10591.9 GBG62621.1 - 0.21 11.9 4.1 0.99 9.7 2.9 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3006 PF11213.8 GBG62621.1 - 0.53 10.6 1.7 1.6 9.0 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) AIF-MLS PF14962.6 GBG62621.1 - 2.9 7.8 6.0 6.1 6.8 6.0 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence LMBR1 PF04791.16 GBG62621.1 - 3.3 6.5 3.6 5 5.9 3.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_L29 PF00831.23 GBG62622.1 - 0.05 13.6 0.9 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein BCAS3 PF12490.8 GBG62623.1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 HTH_23 PF13384.6 GBG62623.1 - 0.22 11.4 2.3 13 5.7 0.2 3.0 3 0 0 3 3 3 0 Homeodomain-like domain AcylCoA_DH_N PF12418.8 GBG62623.1 - 0.51 10.4 3.1 9.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase N terminal zf-CCHC PF00098.23 GBG62625.1 - 0.0012 18.8 4.3 0.0028 17.7 4.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG62625.1 - 0.021 14.6 0.7 0.062 13.0 0.7 1.9 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RNA_pol_Rpc4 PF05132.14 GBG62626.1 - 0.025 15.0 0.7 0.025 15.0 0.7 2.8 2 1 1 3 3 3 0 RNA polymerase III RPC4 RT_RNaseH PF17917.1 GBG62630.1 - 5.5e-26 90.9 0.0 2.4e-25 88.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62630.1 - 3.5e-24 85.6 0.0 5.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62630.1 - 2.3e-18 66.1 0.0 1e-17 64.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4746 PF15928.5 GBG62630.1 - 2 7.8 10.0 3.2 7.1 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC27 PF09507.10 GBG62631.1 - 0.00051 19.6 7.9 0.00072 19.1 7.9 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 TERB2 PF15101.6 GBG62631.1 - 7.4 6.6 8.3 6.9 6.7 6.4 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF561 PF04481.12 GBG62632.1 - 5.8e-56 189.4 0.1 3.4e-46 157.4 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF561) YGGT PF02325.17 GBG62632.1 - 1.1e-10 41.8 1.5 3.7e-10 40.1 1.5 2.0 1 0 0 1 1 1 1 YGGT family DUF561 PF04481.12 GBG62633.1 - 4.2e-62 209.5 0.0 4.8e-59 199.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF561) RT_RNaseH PF17917.1 GBG62634.1 - 2.4e-18 66.4 0.0 4.1e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62634.1 - 1.1e-16 60.7 0.0 2.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62634.1 - 8.3e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG62634.1 - 0.011 16.3 0.2 0.041 14.5 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62634.1 - 0.06 14.0 0.2 0.18 12.5 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease Asp_protease PF09668.10 GBG62634.1 - 0.074 12.8 0.7 0.13 12.0 0.7 1.3 1 0 0 1 1 1 0 Aspartyl protease SICA_C PF12879.7 GBG62634.1 - 0.6 10.1 3.0 1.4 9.0 2.3 1.9 2 0 0 2 2 2 0 SICA C-terminal inner membrane domain gag-asp_proteas PF13975.6 GBG62635.1 - 0.00029 21.3 0.1 0.0026 18.3 0.0 2.5 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62635.1 - 0.0018 18.8 0.0 0.0059 17.2 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 GBG62635.1 - 0.0022 18.0 2.4 0.0022 18.0 2.4 2.6 2 0 0 2 2 2 1 Zinc knuckle API5 PF05918.11 GBG62635.1 - 0.1 11.4 0.0 0.36 9.6 0.0 1.9 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Asp_protease PF09668.10 GBG62635.1 - 0.24 11.2 0.3 0.47 10.3 0.3 1.3 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG62636.1 - 6.9e-35 119.1 0.0 1.3e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62636.1 - 3.3e-29 101.3 0.0 7.6e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62636.1 - 2.4e-27 95.9 0.0 4.8e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG62636.1 - 3.2e-06 26.9 0.0 5.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG62636.1 - 4.9e-05 23.4 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG62636.1 - 0.00053 20.6 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62636.1 - 0.011 16.2 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Peptidase_A3 PF02160.15 GBG62636.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Ribonuc_P_40 PF08584.11 GBG62636.1 - 0.061 12.6 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit RT_RNaseH_2 PF17919.1 GBG62637.1 - 3.3e-27 94.4 0.0 5.7e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62637.1 - 1.1e-23 83.5 0.0 2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62637.1 - 1.4e-19 70.5 0.0 2.4e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG62637.1 - 0.64 10.3 12.2 1 9.6 12.2 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated IHABP4_N PF16174.5 GBG62638.1 - 1.7 9.2 11.0 0.31 11.6 5.6 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal ADK PF00406.22 GBG62639.1 - 1.7e-36 125.6 0.0 2.3e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GBG62639.1 - 1.8e-20 73.7 0.5 3e-20 73.0 0.1 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GBG62639.1 - 0.00031 21.3 0.0 0.00052 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GBG62639.1 - 0.0021 18.3 0.1 0.0056 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GBG62639.1 - 0.14 12.6 0.0 0.52 10.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Homez PF11569.8 GBG62639.1 - 0.19 11.2 0.0 0.42 10.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez UTP15_C PF09384.10 GBG62640.1 - 0.063 13.0 0.9 0.12 12.0 0.9 1.4 1 0 0 1 1 1 0 UTP15 C terminal Transformer PF06495.11 GBG62640.1 - 0.11 12.6 7.9 0.18 11.9 7.9 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein RAI1 PF08652.11 GBG62643.1 - 0.24 11.6 0.1 0.36 11.0 0.1 1.2 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease FHA PF00498.26 GBG62646.1 - 1.6e-08 34.8 0.0 2.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Sec1 PF00995.23 GBG62647.1 - 7.5e-115 385.3 0.0 8.5e-115 385.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TPALS PF18178.1 GBG62647.1 - 0.41 10.0 1.7 7.1 6.0 0.0 3.0 4 0 0 4 4 4 0 TIR- and PNP-associating SLOG family Myb_DNA-bind_7 PF15963.5 GBG62648.1 - 1e-24 86.2 0.8 1e-24 86.2 0.8 2.3 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 GBG62648.1 - 2e-07 31.1 0.0 1.2e-06 28.6 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG62648.1 - 0.019 15.2 0.1 0.058 13.7 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain BUD22 PF09073.10 GBG62648.1 - 0.12 11.7 22.1 0.16 11.2 22.1 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG62648.1 - 1.8 7.9 27.2 2.7 7.3 27.2 1.3 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG62649.1 - 1.7e-27 96.4 0.0 2.6e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62649.1 - 1.4e-16 60.3 0.0 2.8e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62649.1 - 0.00027 21.2 0.0 0.00054 20.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62650.1 - 7.8e-28 97.5 0.1 1.2e-27 96.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5539 PF17693.1 GBG62650.1 - 0.098 12.3 2.5 0.17 11.5 2.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5539) RVT_1 PF00078.27 GBG62652.1 - 3.5e-32 111.7 0.0 5.1e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PEP_mutase PF13714.6 GBG62653.1 - 3.7e-49 167.3 0.5 4.5e-49 167.1 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GBG62653.1 - 1e-13 50.7 0.6 1.3e-13 50.3 0.6 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Glycos_transf_1 PF00534.20 GBG62654.1 - 3.9e-06 26.5 0.1 1.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG62654.1 - 7.5e-05 22.8 0.0 0.5 10.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase Family 4 CDC45 PF02724.14 GBG62654.1 - 0.023 13.0 4.8 0.039 12.2 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_trans_4_4 PF13579.6 GBG62654.1 - 0.032 14.7 0.1 0.15 12.5 0.0 4.4 4 0 0 4 4 4 0 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 GBG62654.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Formyl_trans_N PF00551.19 GBG62654.1 - 0.15 11.8 0.0 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 Formyl transferase Paf1 PF03985.13 GBG62654.1 - 4.7 6.1 10.4 8.6 5.2 10.4 1.3 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 GBG62654.1 - 8.8 5.6 6.8 16 4.7 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein Mpv17_PMP22 PF04117.12 GBG62655.1 - 2.4e-14 53.3 0.1 5.5e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Oleosin PF01277.17 GBG62656.1 - 1.1e-09 38.0 10.1 1.1e-09 38.0 10.1 2.5 2 1 0 2 2 2 1 Oleosin ABC2_membrane_3 PF12698.7 GBG62656.1 - 0.24 10.5 8.7 0.35 9.9 8.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein FtsX PF02687.21 GBG62656.1 - 5.8 7.5 12.0 11 6.5 12.0 1.5 1 1 0 1 1 1 0 FtsX-like permease family DUF2207 PF09972.9 GBG62656.1 - 6.1 5.5 5.6 13 4.4 5.6 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FAD_binding_2 PF00890.24 GBG62659.1 - 1.4e-121 406.5 4.4 1.7e-121 406.2 4.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GBG62659.1 - 3.7e-43 146.6 0.4 5.5e-43 146.0 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 GBG62659.1 - 0.00018 20.9 0.1 0.00056 19.2 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GBG62659.1 - 0.00056 19.1 0.9 0.045 12.8 1.8 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GBG62659.1 - 0.0021 17.4 0.2 0.0032 16.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GBG62659.1 - 0.0084 15.7 0.7 0.032 13.8 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GBG62659.1 - 0.015 14.6 0.8 0.29 10.3 0.1 2.3 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 GBG62659.1 - 0.066 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 GBG62659.1 - 0.13 11.0 1.2 0.23 10.1 0.4 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 GBG62659.1 - 0.38 10.0 1.6 1.6 7.9 0.8 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase cNMP_binding PF00027.29 GBG62661.1 - 6.6e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 GBG62661.1 - 0.091 12.0 1.3 0.13 11.5 1.3 1.2 1 0 0 1 1 1 0 Ion transport protein Ion_trans PF00520.31 GBG62662.1 - 2.9e-32 111.9 23.1 1.1e-19 70.6 10.4 2.2 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 GBG62662.1 - 2.2e-06 27.6 0.0 4.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Atx10homo_assoc PF09759.9 GBG62663.1 - 2.7e-32 110.7 0.2 7.9e-31 106.0 0.0 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain RNA_pol_Rbc25 PF08292.12 GBG62664.1 - 1.2e-08 35.3 0.1 0.00031 21.0 0.2 2.7 2 1 0 2 2 2 2 RNA polymerase III subunit Rpc25 DnaJ PF00226.31 GBG62665.1 - 4.6e-23 81.1 0.5 1.3e-22 79.7 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain Nefa_Nip30_N PF10187.9 GBG62665.1 - 0.0082 16.5 1.7 0.0082 16.5 1.7 3.3 3 0 0 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 gag-asp_proteas PF13975.6 GBG62667.1 - 5.8e-07 30.0 0.0 1.6e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62667.1 - 3.3e-06 27.7 0.0 1.2e-05 25.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 GBG62667.1 - 0.0063 16.5 2.5 0.014 15.4 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG62667.1 - 0.041 13.6 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62667.1 - 0.062 13.1 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease ZapB PF06005.12 GBG62668.1 - 0.009 16.4 7.9 0.009 16.4 7.9 3.7 4 2 0 4 4 4 1 Cell division protein ZapB Prominin PF05478.11 GBG62668.1 - 0.035 12.1 3.8 0.056 11.4 3.8 1.2 1 0 0 1 1 1 0 Prominin Snapin_Pallidin PF14712.6 GBG62668.1 - 0.062 13.7 6.7 1.9 9.0 3.1 2.5 2 0 0 2 2 2 0 Snapin/Pallidin kleA_kleC PF17383.2 GBG62668.1 - 0.067 13.5 1.9 0.28 11.5 1.9 2.1 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Bacillus_HBL PF05791.11 GBG62668.1 - 0.5 10.2 4.0 0.29 11.0 2.0 1.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Cep57_MT_bd PF06657.13 GBG62668.1 - 0.66 10.5 11.0 0.036 14.5 4.5 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF948 PF06103.11 GBG62668.1 - 1.9 8.8 3.5 2.2 8.6 1.6 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-CCHC PF00098.23 GBG62668.1 - 9.1 6.6 7.2 17 5.7 7.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Spt20 PF12090.8 GBG62669.1 - 2.9e-15 56.5 0.0 2.9e-15 56.5 0.0 7.0 6 2 0 6 6 6 2 Spt20 family TFIIF_beta PF02270.15 GBG62670.1 - 3.5e-24 84.7 0.3 7e-24 83.7 0.3 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 GBG62670.1 - 2.5e-10 41.2 0.0 5.8e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus U-box PF04564.15 GBG62671.1 - 5.7e-18 64.9 0.0 1.3e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GBG62671.1 - 0.0068 16.2 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nop14 PF04147.12 GBG62671.1 - 0.26 9.5 43.5 0.11 10.7 20.5 2.2 2 0 0 2 2 2 0 Nop14-like family RR_TM4-6 PF06459.12 GBG62671.1 - 3.7 7.3 23.2 3.7 7.3 2.7 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_3_Rpc31 PF11705.8 GBG62671.1 - 7.6 6.7 46.4 16 5.7 24.1 3.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF913 PF06025.12 GBG62671.1 - 9.7 5.1 11.7 5.9 5.7 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FAT PF02259.23 GBG62672.1 - 1.2e-31 110.2 14.8 1.4e-26 93.6 0.1 3.0 3 0 0 3 3 3 2 FAT domain PI3_PI4_kinase PF00454.27 GBG62672.1 - 2.1e-05 24.5 0.1 6.4e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GBG62672.1 - 2.9e-05 23.8 1.1 7.1e-05 22.5 0.1 2.3 2 0 0 2 2 2 1 FATC domain Urb2 PF10441.9 GBG62672.1 - 1.2 9.1 4.6 9.3 6.1 0.0 4.0 3 1 0 3 3 3 0 Urb2/Npa2 family FAT PF02259.23 GBG62673.1 - 1.2e-31 110.2 14.8 1.4e-26 93.5 0.1 3.0 3 0 0 3 3 3 2 FAT domain PI3_PI4_kinase PF00454.27 GBG62673.1 - 2.1e-05 24.5 0.1 6.4e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GBG62673.1 - 2.9e-05 23.8 1.1 7.1e-05 22.5 0.1 2.3 2 0 0 2 2 2 1 FATC domain Urb2 PF10441.9 GBG62673.1 - 1.2 9.1 4.6 9.3 6.1 0.0 4.0 3 1 0 3 3 3 0 Urb2/Npa2 family FAT PF02259.23 GBG62674.1 - 1.1e-31 110.3 14.8 1.4e-26 93.6 0.1 3.0 3 0 0 3 3 3 2 FAT domain PI3_PI4_kinase PF00454.27 GBG62674.1 - 2.1e-05 24.5 0.1 6.3e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GBG62674.1 - 2.9e-05 23.8 1.1 7e-05 22.6 0.1 2.3 2 0 0 2 2 2 1 FATC domain Urb2 PF10441.9 GBG62674.1 - 0.15 12.0 3.6 2.3 8.1 0.0 4.0 3 1 0 3 3 3 0 Urb2/Npa2 family Peptidase_C48 PF02902.19 GBG62675.1 - 2.1e-23 83.3 0.1 4.2e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Nodulin_late PF07127.11 GBG62675.1 - 0.82 10.1 3.1 6.3 7.2 3.1 2.7 1 0 0 1 1 1 0 Late nodulin protein DUF659 PF04937.15 GBG62676.1 - 1.6e-13 50.8 0.0 2.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PolyA_pol_arg_C PF12626.7 GBG62676.1 - 0.033 14.2 1.8 2 8.5 0.4 2.5 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus zinc_ribbon_4 PF13717.6 GBG62676.1 - 0.13 12.2 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain RVT_1 PF00078.27 GBG62677.1 - 3.1e-20 72.6 0.0 5.7e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62677.1 - 7.2e-19 67.6 0.1 2.2e-18 66.1 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62677.1 - 9.1e-07 29.1 0.0 4e-06 27.0 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG62677.1 - 2.8e-05 24.6 0.0 0.00013 22.6 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62677.1 - 3.3e-05 24.3 0.0 0.00011 22.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62677.1 - 3.5e-05 23.6 0.0 7.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG62677.1 - 0.13 12.6 0.1 0.86 9.9 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Chromo PF00385.24 GBG62677.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_4 PF13837.6 GBG62678.1 - 2e-11 44.1 0.5 2e-11 44.1 0.5 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG62678.1 - 0.023 14.9 0.2 0.06 13.5 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG62678.1 - 0.038 14.3 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Na_H_Exchanger PF00999.21 GBG62679.1 - 1.5e-62 211.6 32.8 1.8e-62 211.3 32.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MNHE PF01899.16 GBG62679.1 - 6.4 6.5 9.5 0.21 11.3 1.3 2.7 2 2 0 2 2 2 0 Na+/H+ ion antiporter subunit GRAM PF02893.20 GBG62680.1 - 0.0089 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 GRAM domain PH_2 PF08458.10 GBG62680.1 - 0.029 14.7 0.2 0.068 13.5 0.2 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Dimer_Tnp_hAT PF05699.14 GBG62682.1 - 2.3e-07 30.5 1.2 4e-07 29.7 0.2 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DeoC PF01791.9 GBG62682.1 - 0.011 15.3 0.2 0.027 14.1 0.2 1.5 1 0 0 1 1 1 0 DeoC/LacD family aldolase NYD-SP12_N PF15015.6 GBG62682.1 - 0.33 9.3 0.0 0.33 9.3 0.0 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated, N-terminal HC2 PF07382.11 GBG62683.1 - 0.017 15.2 3.9 0.034 14.2 3.9 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 FKBP_C PF00254.28 GBG62684.1 - 1.1e-09 38.5 0.0 3.6e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_transf_8 PF01501.20 GBG62685.1 - 8.1e-22 78.0 0.0 1.2e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nop14 PF04147.12 GBG62685.1 - 5 5.2 12.1 8.3 4.5 12.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG62685.1 - 5.2 5.2 7.3 8.5 4.5 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Snf7 PF03357.21 GBG62687.1 - 1.6e-40 138.5 14.8 2.1e-40 138.2 14.8 1.1 1 0 0 1 1 1 1 Snf7 DnaJ-X PF14308.6 GBG62687.1 - 0.0091 15.5 2.8 0.0091 15.5 2.8 1.8 1 1 1 2 2 2 1 X-domain of DnaJ-containing Hemagglutinin PF00509.18 GBG62687.1 - 0.052 12.0 0.4 0.075 11.4 0.4 1.1 1 0 0 1 1 1 0 Haemagglutinin PspA_IM30 PF04012.12 GBG62687.1 - 0.095 12.3 13.0 0.14 11.7 4.5 2.1 1 1 1 2 2 2 0 PspA/IM30 family YlqD PF11068.8 GBG62687.1 - 2.4 8.6 12.3 0.3 11.5 2.2 2.2 1 1 1 2 2 2 0 YlqD protein Snf7 PF03357.21 GBG62688.1 - 1.3e-40 138.8 13.3 1.6e-40 138.6 13.3 1.1 1 0 0 1 1 1 1 Snf7 DnaJ-X PF14308.6 GBG62688.1 - 0.0033 16.9 2.6 0.0033 16.9 2.6 1.4 2 0 0 2 2 2 1 X-domain of DnaJ-containing Hemagglutinin PF00509.18 GBG62688.1 - 0.025 13.0 0.3 0.033 12.6 0.3 1.1 1 0 0 1 1 1 0 Haemagglutinin Mce4_CUP1 PF11887.8 GBG62688.1 - 0.088 12.2 0.5 0.12 11.8 0.5 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative PspA_IM30 PF04012.12 GBG62688.1 - 0.21 11.1 11.7 0.053 13.1 4.2 2.1 1 1 0 2 2 2 0 PspA/IM30 family YlqD PF11068.8 GBG62688.1 - 0.99 9.8 10.8 77 3.7 10.8 2.2 1 1 0 1 1 1 0 YlqD protein Cytochrom_B562 PF07361.11 GBG62688.1 - 7.9 7.2 11.2 15 6.3 0.3 2.5 2 1 0 2 2 2 0 Cytochrome b562 Seryl_tRNA_N PF02403.22 GBG62688.1 - 8.7 6.6 10.5 11 6.3 1.2 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Cellulose_synt PF03552.14 GBG62690.1 - 0 1166.9 0.1 0 1166.6 0.1 1.1 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.6 GBG62690.1 - 2.9e-12 46.5 9.5 2.9e-12 46.5 9.5 2.8 3 0 0 3 3 3 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 GBG62690.1 - 9.6e-12 44.5 12.3 2.2e-11 43.3 12.3 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Glycos_transf_2 PF00535.26 GBG62690.1 - 0.00024 20.9 0.1 0.00055 19.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG62690.1 - 0.016 15.1 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Saf-Nte_pilin PF09460.10 GBG62692.1 - 0.0044 17.1 0.2 0.0085 16.1 0.2 1.4 1 0 0 1 1 1 1 Saf-pilin pilus formation protein Chlam_PMP PF02415.17 GBG62692.1 - 0.25 11.9 0.2 0.25 11.9 0.2 5.3 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat CCDC53 PF10152.9 GBG62693.1 - 0.027 14.9 6.9 1.9 8.9 3.0 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CDC45 PF02724.14 GBG62693.1 - 0.3 9.3 8.7 0.45 8.7 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein MID_MedPIWI PF18296.1 GBG62693.1 - 0.43 10.3 5.4 7.5 6.3 0.1 2.2 2 0 0 2 2 2 0 MID domain of medPIWI CobT PF06213.12 GBG62693.1 - 0.48 9.8 12.3 0.85 9.0 12.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIB PF00382.19 GBG62695.1 - 6e-28 96.7 3.7 1.5e-15 57.0 0.1 3.3 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 GBG62695.1 - 5e-25 87.8 2.1 5e-25 87.8 2.1 3.5 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 GBG62695.1 - 4.4e-06 26.1 1.9 4.4e-06 26.1 1.9 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 GBG62695.1 - 0.057 13.2 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 0 Cyclin, N-terminal domain GFO_IDH_MocA PF01408.22 GBG62697.1 - 1.4e-13 51.7 0.1 4.2e-13 50.2 0.1 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF1995 PF09353.10 GBG62697.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) GFO_IDH_MocA_C PF02894.17 GBG62697.1 - 0.017 15.1 0.1 0.036 14.1 0.1 1.7 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Myb_DNA-bind_4 PF13837.6 GBG62698.1 - 9.5e-10 38.7 0.4 6.5e-08 32.8 0.1 2.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain HemY_N PF07219.13 GBG62698.1 - 0.098 12.9 0.2 0.65 10.2 0.0 2.3 2 0 0 2 2 2 0 HemY protein N-terminus DDE_Tnp_4 PF13359.6 GBG62699.1 - 7.6e-30 103.7 0.0 1.1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62699.1 - 3.3e-16 59.5 0.0 5.2e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG62699.1 - 8e-06 25.6 0.1 0.0089 15.7 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG62699.1 - 0.15 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Sel1 PF08238.12 GBG62701.1 - 7.8e-08 32.8 0.2 0.00056 20.5 0.0 2.9 2 0 0 2 2 2 2 Sel1 repeat Chromo PF00385.24 GBG62701.1 - 0.0015 18.4 0.0 0.0058 16.5 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG62702.1 - 8.5e-08 32.7 0.0 2.2e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62702.1 - 6.1e-07 29.9 0.0 1.7e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62702.1 - 1.3e-06 28.2 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG62702.1 - 0.0018 17.8 0.1 0.0051 16.3 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG62702.1 - 0.002 18.4 2.0 0.0031 17.8 0.1 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG62702.1 - 0.01 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Chromo PF00385.24 GBG62702.1 - 0.11 12.4 2.1 0.089 12.7 0.3 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Sel1 PF08238.12 GBG62703.1 - 1.7e-94 308.1 47.3 8.6e-11 42.2 0.8 10.3 10 0 0 10 10 10 10 Sel1 repeat TPR_6 PF13174.6 GBG62703.1 - 8.8e-08 32.3 19.2 0.36 11.5 0.2 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat NEMP PF10225.9 GBG62703.1 - 0.011 15.4 0.3 4.6 6.8 0.0 4.2 3 2 2 5 5 5 0 NEMP family TPR_16 PF13432.6 GBG62703.1 - 1.2 9.9 34.6 9 7.0 3.9 6.4 3 2 4 7 7 7 0 Tetratricopeptide repeat Sel1 PF08238.12 GBG62704.1 - 2.1e-34 117.2 32.7 7e-09 36.1 3.9 7.4 8 0 0 8 8 8 6 Sel1 repeat TPR_6 PF13174.6 GBG62704.1 - 0.00013 22.4 13.6 0.053 14.2 0.1 6.3 3 1 3 6 6 6 2 Tetratricopeptide repeat Nop14 PF04147.12 GBG62705.1 - 5.8 5.0 8.7 7.4 4.6 8.7 1.0 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG62706.1 - 4.3e-25 88.6 0.1 6.9e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62706.1 - 1.4e-15 57.1 0.3 5.5e-15 55.2 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG62706.1 - 1.8e-08 34.6 0.0 6.3e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG62706.1 - 3.4e-05 23.6 0.0 8.7e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG62706.1 - 0.00011 22.4 0.1 0.00024 21.3 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger BUD22 PF09073.10 GBG62707.1 - 0.4 10.0 16.7 0.62 9.4 16.7 1.2 1 0 0 1 1 1 0 BUD22 Unstab_antitox PF09720.10 GBG62707.1 - 0.55 10.3 9.2 4.1 7.5 3.3 2.7 2 0 0 2 2 2 0 Putative addiction module component LAP1C PF05609.12 GBG62707.1 - 0.55 9.3 6.8 0.85 8.6 6.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MSA-2c PF12238.8 GBG62707.1 - 5.6 6.9 6.0 8 6.4 6.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c CDC45 PF02724.14 GBG62707.1 - 8.7 4.5 12.1 12 4.1 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG62708.1 - 7.5e-12 45.4 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF737 PF05300.11 GBG62708.1 - 0.19 12.1 0.9 0.36 11.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CAP PF00188.26 GBG62709.1 - 5.7e-23 82.1 10.1 1.1e-22 81.2 10.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pinin_SDK_N PF04697.13 GBG62709.1 - 8.4 7.0 6.1 6.9 7.3 2.6 2.0 1 1 1 2 2 2 0 pinin/SDK conserved region RVT_1 PF00078.27 GBG62710.1 - 1.4e-30 106.5 0.1 2.3e-30 105.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62710.1 - 7.3e-17 61.3 0.0 1.1e-11 44.7 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62710.1 - 5.9e-16 58.3 1.3 1.3e-15 57.3 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG62710.1 - 4.4e-12 45.7 0.0 1.1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG62710.1 - 2.2e-10 40.8 0.0 1.3e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG62710.1 - 2.6e-07 30.9 0.0 7.7e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG62710.1 - 5.1e-05 23.4 0.0 0.00019 21.6 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger CAP PF00188.26 GBG62714.1 - 4.3e-21 76.1 11.1 6.8e-21 75.4 11.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pinin_SDK_N PF04697.13 GBG62714.1 - 6.7 7.4 5.6 1.7 9.3 1.7 1.8 1 1 1 2 2 2 0 pinin/SDK conserved region Peptidase_C48 PF02902.19 GBG62717.1 - 8.2e-07 29.1 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Spt20 PF12090.8 GBG62719.1 - 0.061 12.9 0.5 0.084 12.5 0.5 1.3 1 0 0 1 1 1 0 Spt20 family zf-CCHC PF00098.23 GBG62719.1 - 1.5 9.1 8.8 0.49 10.6 6.0 1.7 2 0 0 2 2 2 0 Zinc knuckle Mei5 PF10376.9 GBG62721.1 - 0.0059 16.5 0.2 0.0059 16.5 0.2 2.0 1 1 0 2 2 2 1 Double-strand recombination repair protein Hrs_helical PF12210.8 GBG62721.1 - 0.013 16.0 1.6 0.094 13.3 0.0 2.4 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate IL5 PF02025.15 GBG62721.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Interleukin 5 TolA_bind_tri PF16331.5 GBG62721.1 - 0.4 10.8 6.3 2.5 8.3 0.3 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation CENP-Q PF13094.6 GBG62721.1 - 2.6 8.2 13.3 15 5.8 13.3 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RT_RNaseH_2 PF17919.1 GBG62723.1 - 7.6e-12 45.1 0.0 1.8e-11 44.0 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62723.1 - 7e-10 38.8 0.1 9.1e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62723.1 - 0.00054 20.2 0.0 0.0015 18.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG62723.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 CAP PF00188.26 GBG62724.1 - 2.8e-20 73.4 7.6 4.4e-20 72.8 7.6 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 GBG62725.1 - 2e-22 80.4 2.5 2.6e-22 80.0 2.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TolA_bind_tri PF16331.5 GBG62726.1 - 0.011 15.8 1.8 1.2 9.2 0.5 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation Mto2_bdg PF12808.7 GBG62726.1 - 0.082 13.2 1.5 0.082 13.2 1.5 3.4 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CCDC92 PF14916.6 GBG62726.1 - 0.42 10.4 3.7 1.7 8.4 0.6 3.1 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Ycf1 PF05758.12 GBG62726.1 - 0.52 8.1 8.4 0.75 7.6 8.4 1.1 1 0 0 1 1 1 0 Ycf1 Atrophin-1 PF03154.15 GBG62726.1 - 1.3 7.2 4.6 1.7 6.8 4.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family Pox_A_type_inc PF04508.12 GBG62726.1 - 4.1 7.4 9.0 5.5 7.0 1.5 3.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DivIC PF04977.15 GBG62726.1 - 4.7 7.1 16.2 0.43 10.4 0.4 3.6 2 1 2 4 4 4 0 Septum formation initiator NYD-SP28_assoc PF14775.6 GBG62726.1 - 5.6 7.1 7.8 1.2 9.3 0.3 3.1 4 0 0 4 4 4 0 Sperm tail C-terminal domain DUF1835 PF08874.10 GBG62726.1 - 7 6.9 9.2 43 4.4 9.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1835) Peptidase_S8 PF00082.22 GBG62728.1 - 3e-38 131.8 0.1 5.8e-38 130.8 0.1 1.5 1 0 0 1 1 1 1 Subtilase family Gp_dh_C PF02800.20 GBG62729.1 - 2.8e-69 231.7 0.0 4.4e-69 231.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG62729.1 - 2e-30 105.1 0.0 4.3e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 GBG62729.1 - 0.031 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PseudoU_synth_1 PF01416.20 GBG62731.1 - 1.5e-29 102.7 0.0 2.9e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridine synthase rve PF00665.26 GBG62732.1 - 3.4e-15 56.3 0.1 1e-14 54.7 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG62732.1 - 0.0031 17.8 0.3 0.035 14.4 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Myb_DNA-bind_4 PF13837.6 GBG62733.1 - 3.1e-09 37.1 0.7 5.6e-09 36.3 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RsgA_GTPase PF03193.16 GBG62736.1 - 1.6e-06 28.1 0.0 4.8e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 GBG62736.1 - 2.3e-06 27.6 0.0 1.5e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GBG62736.1 - 6.9e-05 23.3 6.5 0.00016 22.1 0.0 3.7 5 0 0 5 5 3 1 AAA ATPase domain AIG1 PF04548.16 GBG62736.1 - 0.00027 20.3 0.0 0.4 10.0 0.0 2.5 2 0 0 2 2 2 2 AIG1 family AAA_29 PF13555.6 GBG62736.1 - 0.0016 18.2 0.0 0.0061 16.3 0.0 2.0 2 0 0 2 2 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 GBG62736.1 - 0.0041 16.3 0.1 0.04 13.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 GBG62736.1 - 0.0041 16.6 0.0 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region Septin PF00735.18 GBG62736.1 - 0.0061 15.9 0.1 0.029 13.7 0.1 2.0 1 1 0 1 1 1 1 Septin G-alpha PF00503.20 GBG62736.1 - 0.0064 15.7 0.0 0.019 14.1 0.0 1.7 1 0 0 1 1 1 1 G-protein alpha subunit TniB PF05621.11 GBG62736.1 - 0.015 14.7 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 GBG62736.1 - 0.02 15.4 0.0 0.095 13.2 0.0 2.2 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 GBG62736.1 - 0.02 14.0 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 GBG62736.1 - 0.029 14.6 0.0 0.14 12.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GBG62736.1 - 0.035 13.8 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 GBG62736.1 - 0.037 13.4 0.1 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 GBG62736.1 - 0.056 13.5 0.8 5.5 7.0 0.1 3.0 2 1 0 2 2 1 0 Dynamin family Sigma54_activ_2 PF14532.6 GBG62736.1 - 0.073 13.2 0.0 0.34 11.0 0.0 2.2 1 0 0 1 1 1 0 Sigma-54 interaction domain IIGP PF05049.13 GBG62736.1 - 0.085 11.9 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 GBG62736.1 - 0.096 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 GBG62736.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GBG62736.1 - 0.13 12.6 0.1 0.88 10.0 0.0 2.4 3 0 0 3 3 2 0 RNA helicase GTP_EFTU PF00009.27 GBG62736.1 - 0.17 11.4 0.1 0.66 9.5 0.0 2.1 2 0 0 2 2 1 0 Elongation factor Tu GTP binding domain DASH_Dam1 PF08653.10 GBG62736.1 - 0.33 10.8 5.2 0.38 10.6 0.1 3.0 3 0 0 3 3 2 0 DASH complex subunit Dam1 TSC22 PF01166.18 GBG62736.1 - 0.43 10.9 3.3 0.36 11.2 0.6 2.4 2 0 0 2 2 1 0 TSC-22/dip/bun family AAA_23 PF13476.6 GBG62736.1 - 0.48 10.9 0.0 0.48 10.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain GrpE PF01025.19 GBG62736.1 - 2.8 7.6 11.9 0.1 12.2 4.6 2.2 2 0 0 2 2 2 0 GrpE MMR_HSR1 PF01926.23 GBG62737.1 - 5.3e-06 26.5 0.0 3.9e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GBG62737.1 - 6.5e-06 25.6 0.8 0.015 14.6 0.0 2.9 3 0 0 3 3 2 2 AIG1 family RsgA_GTPase PF03193.16 GBG62737.1 - 7e-06 26.0 1.0 1.7e-05 24.8 0.0 2.1 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 GBG62737.1 - 0.00023 21.6 0.1 0.0011 19.4 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA_23 PF13476.6 GBG62737.1 - 0.00024 21.6 2.9 0.032 14.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 GBG62737.1 - 0.00029 20.1 0.5 0.0013 18.0 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Septin PF00735.18 GBG62737.1 - 0.0003 20.2 0.1 0.0012 18.2 0.1 2.0 1 1 0 1 1 1 1 Septin IIGP PF05049.13 GBG62737.1 - 0.00077 18.6 1.0 0.0025 16.9 0.0 2.3 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 GBG62737.1 - 0.0026 17.4 0.0 0.0026 17.4 0.0 2.1 2 0 0 2 2 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 GBG62737.1 - 0.0029 16.7 0.6 0.0055 15.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF815 PF05673.13 GBG62737.1 - 0.0044 16.2 0.0 0.083 12.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) EMP24_GP25L PF01105.24 GBG62737.1 - 0.0078 16.2 0.7 0.021 14.8 0.7 1.7 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AAA_7 PF12775.7 GBG62737.1 - 0.0085 15.6 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 GBG62737.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 GBG62737.1 - 0.023 15.2 0.2 0.21 12.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 GBG62737.1 - 0.027 14.7 0.0 0.093 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GBG62737.1 - 0.033 14.3 2.5 4.7 7.2 0.1 3.3 2 1 0 2 2 2 0 Dynamin family Roc PF08477.13 GBG62737.1 - 0.04 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 GBG62737.1 - 0.041 13.6 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain MCM PF00493.23 GBG62737.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain TSC22 PF01166.18 GBG62737.1 - 0.08 13.3 2.4 0.092 13.1 0.3 2.3 2 0 0 2 2 1 0 TSC-22/dip/bun family RNA_helicase PF00910.22 GBG62737.1 - 0.081 13.3 0.0 0.29 11.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.27 GBG62737.1 - 0.091 12.3 1.2 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 GBG62737.1 - 0.092 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 GBG62737.1 - 0.097 12.0 0.1 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family DASH_Dad2 PF08654.10 GBG62737.1 - 0.1 13.0 4.4 3.4 8.1 1.4 3.7 4 0 0 4 4 4 0 DASH complex subunit Dad2 DUF87 PF01935.17 GBG62737.1 - 0.11 12.5 3.5 3 7.9 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain V_ATPase_I PF01496.19 GBG62737.1 - 0.13 10.1 2.0 0.25 9.2 2.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family L31 PF09784.9 GBG62737.1 - 0.15 12.5 2.0 0.23 11.9 0.4 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 GrpE PF01025.19 GBG62737.1 - 0.22 11.2 6.7 0.55 9.9 6.7 1.6 1 0 0 1 1 1 0 GrpE DivIC PF04977.15 GBG62737.1 - 2.5 7.9 9.6 0.3 10.9 4.4 2.1 2 0 0 2 2 2 0 Septum formation initiator CENP-K PF11802.8 GBG62737.1 - 4.3 6.8 8.6 1.2 8.6 4.3 2.2 3 0 0 3 3 2 0 Centromere-associated protein K KxDL PF10241.9 GBG62737.1 - 5.3 7.4 8.0 3.2 8.1 0.4 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein Csm1_N PF18504.1 GBG62737.1 - 5.4 7.4 7.9 1.8 9.0 4.1 2.1 2 0 0 2 2 1 0 Csm1 N-terminal domain DDE_Tnp_4 PF13359.6 GBG62738.1 - 0.05 13.3 0.1 0.096 12.3 0.1 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF659 PF04937.15 GBG62739.1 - 3.5e-30 104.9 0.3 6.5e-30 104.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG62741.1 - 1.3e-06 28.2 2.9 2.4e-06 27.3 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG62742.1 - 3.3e-14 52.9 0.1 6.2e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG62742.1 - 4.6e-14 52.6 0.0 1.2e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG62742.1 - 1.3e-07 31.6 0.0 3.3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG62742.1 - 2.3e-05 24.5 0.0 6.3e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG62742.1 - 0.00063 19.7 0.3 0.0048 16.9 0.1 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG62742.1 - 0.028 14.2 0.0 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain FHA PF00498.26 GBG62743.1 - 1.1e-05 25.7 0.1 3.2e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GBG62743.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Gln-synt_C PF00120.24 GBG62747.1 - 3.5e-12 46.0 0.0 4.4e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG62747.1 - 1.6e-10 40.6 0.0 2.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RVT_1 PF00078.27 GBG62747.1 - 4.3e-06 26.4 0.0 7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glycolytic PF00274.19 GBG62748.1 - 3e-63 213.7 0.0 3.7e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Peptidase_M61 PF05299.12 GBG62748.1 - 0.043 14.2 0.0 0.086 13.2 0.0 1.5 2 0 0 2 2 2 0 M61 glycyl aminopeptidase Gln-synt_C PF00120.24 GBG62749.1 - 9e-14 51.2 0.0 2.5e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG62749.1 - 1.3e-10 40.8 0.0 3.9e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF5103 PF17116.5 GBG62751.1 - 0.26 10.5 0.2 3.6 6.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5103) Glycolytic PF00274.19 GBG62752.1 - 4.6e-169 561.7 0.0 5.2e-169 561.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Myb_DNA-bind_4 PF13837.6 GBG62753.1 - 4.3e-07 30.2 0.6 8.9e-07 29.2 0.6 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG62753.1 - 0.0053 16.8 0.8 0.0079 16.3 0.1 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Glycolytic PF00274.19 GBG62754.1 - 5.1e-127 423.4 0.2 3.8e-85 285.7 0.1 2.0 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-I DUF659 PF04937.15 GBG62755.1 - 1.4e-16 60.7 0.0 2.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Gln-synt_C PF00120.24 GBG62756.1 - 1.1e-14 54.2 0.0 6.9e-12 45.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG62756.1 - 3.4e-11 42.7 0.0 5.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain VIT1 PF01988.19 GBG62757.1 - 8.3e-56 189.2 4.9 1e-55 189.0 4.9 1.1 1 0 0 1 1 1 1 VIT family DUF659 PF04937.15 GBG62758.1 - 6.9e-15 55.2 0.0 1.7e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CitMHS PF03600.16 GBG62758.1 - 0.00044 19.6 6.8 0.00057 19.2 6.8 1.2 1 0 0 1 1 1 1 Citrate transporter OmpH PF03938.14 GBG62758.1 - 1.3 9.3 0.0 1.3 9.3 0.0 3.9 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) AT_hook PF02178.19 GBG62758.1 - 1.4 9.0 25.5 0.1 12.5 3.9 3.2 3 0 0 3 3 3 0 AT hook motif Glycolytic PF00274.19 GBG62759.1 - 2.6e-170 565.7 0.0 3.1e-170 565.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Gln-synt_C PF00120.24 GBG62760.1 - 7.9e-15 54.7 0.0 5.1e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG62760.1 - 4.7e-11 42.3 0.0 8.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RT_RNaseH_2 PF17919.1 GBG62761.1 - 6.6e-27 93.5 0.0 1.4e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62761.1 - 3.4e-20 72.5 0.0 7.5e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62761.1 - 8.1e-17 61.4 0.2 3.6e-13 49.7 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62762.1 - 2.4e-26 92.6 0.2 4.7e-26 91.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 GBG62762.1 - 9.9e-16 57.3 5.4 4.7e-09 35.9 2.8 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GBG62762.1 - 8.4e-11 41.9 9.6 3.2e-06 27.4 0.5 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Spindle_Spc25 PF08234.12 GBG62762.1 - 1.3e-08 34.9 0.0 7.3e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 LRR_1 PF00560.33 GBG62762.1 - 0.11 13.1 7.7 42 5.2 0.0 5.5 4 1 0 4 4 4 0 Leucine Rich Repeat YabA PF06156.13 GBG62762.1 - 0.26 11.9 6.8 14 6.4 0.0 3.5 3 0 0 3 3 3 0 Initiation control protein YabA CENP-H PF05837.12 GBG62762.1 - 0.32 11.4 11.6 38 4.7 10.9 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Nup54 PF13874.6 GBG62762.1 - 0.52 10.4 5.4 0.33 11.1 2.5 2.2 2 0 0 2 2 1 0 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.12 GBG62762.1 - 0.61 10.1 7.8 0.42 10.6 2.2 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 GBG62762.1 - 0.71 9.4 14.1 0.087 12.4 7.6 2.2 2 0 0 2 2 2 0 Intermediate filament protein DHR10 PF18595.1 GBG62762.1 - 0.81 9.8 22.9 0.014 15.4 13.9 2.6 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain FliD_N PF02465.18 GBG62762.1 - 0.85 10.4 5.3 14 6.5 1.2 2.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ApoLp-III PF07464.11 GBG62762.1 - 1.1 9.3 9.5 0.32 11.1 5.7 2.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Spc7 PF08317.11 GBG62762.1 - 1.7 7.5 15.2 0.064 12.1 8.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 GBG62762.1 - 2 8.9 11.8 0.28 11.6 6.9 2.0 2 0 0 2 2 2 0 Fez1 KLRAQ PF10205.9 GBG62762.1 - 3.4 8.0 8.9 1.4 9.2 5.8 1.9 2 0 0 2 2 1 0 Predicted coiled-coil domain-containing protein MCPsignal PF00015.21 GBG62762.1 - 5.5 6.8 8.3 1.5 8.6 3.8 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SesA PF17107.5 GBG62762.1 - 6.3 7.0 8.6 11 6.2 3.5 3.2 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 GBG62762.1 - 7.8 7.0 7.9 21 5.7 0.8 3.7 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein RT_RNaseH PF17917.1 GBG62763.1 - 9.1e-23 80.6 0.0 1.8e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62763.1 - 4.5e-22 78.0 0.0 1.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG62763.1 - 0.089 13.1 0.1 0.26 11.6 0.1 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein Drf_GBD PF06371.13 GBG62763.1 - 0.093 12.3 0.3 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Myb_DNA-binding PF00249.31 GBG62764.1 - 3e-25 88.1 7.2 7.2e-13 48.5 0.6 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG62764.1 - 4.8e-20 71.6 1.6 1.6e-09 37.8 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 GBG62764.1 - 0.00044 20.3 0.0 0.051 13.7 0.0 2.9 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 GBG62764.1 - 0.0019 18.0 5.8 0.0028 17.5 0.2 3.0 3 0 0 3 3 3 1 Myb DNA-binding like Sigma70_r4_2 PF08281.12 GBG62764.1 - 0.069 12.8 0.5 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 SLIDE PF09111.10 GBG62764.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.3 3 1 1 4 4 4 0 SLIDE NST1 PF13945.6 GBG62764.1 - 6.8 6.8 23.3 0.81 9.8 12.9 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF3807 PF12720.7 GBG62765.1 - 0.0035 17.6 17.3 0.0058 16.9 17.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) SLC12 PF03522.15 GBG62765.1 - 0.078 12.0 9.3 0.11 11.5 9.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DDHD PF02862.17 GBG62765.1 - 0.27 11.4 3.2 0.42 10.7 3.2 1.2 1 0 0 1 1 1 0 DDHD domain DAG_kinase_N PF14513.6 GBG62765.1 - 0.29 11.3 5.8 0.47 10.6 5.8 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus TAF4 PF05236.14 GBG62765.1 - 0.56 9.9 27.3 1.1 8.9 27.3 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RNA_polI_A34 PF08208.11 GBG62765.1 - 0.66 10.0 37.6 1.2 9.2 37.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNA_pol_Rpc4 PF05132.14 GBG62765.1 - 1.2 9.5 14.6 2.9 8.3 14.6 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 SRP-alpha_N PF04086.13 GBG62765.1 - 1.3 8.9 28.7 2.5 8.0 28.7 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4776 PF16003.5 GBG62765.1 - 1.7 7.5 18.5 2.6 7.0 18.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Sec62 PF03839.16 GBG62765.1 - 2 7.9 17.8 4.8 6.6 17.8 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 CPSF100_C PF13299.6 GBG62765.1 - 2.3 8.4 14.7 6.3 6.9 14.7 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AAA_11 PF13086.6 GBG62765.1 - 3.2 7.5 12.7 5.2 6.8 12.7 1.3 1 0 0 1 1 1 0 AAA domain DUF1764 PF08576.10 GBG62765.1 - 3.2 8.7 24.9 8.3 7.4 24.9 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Membralin PF09746.9 GBG62765.1 - 7.5 5.5 5.4 12 4.8 5.4 1.2 1 0 0 1 1 1 0 Tumour-associated protein Ribosomal_S8e PF01201.22 GBG62767.1 - 3.5e-54 182.7 1.4 4.2e-54 182.4 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e gag-asp_proteas PF13975.6 GBG62768.1 - 1.1e-07 32.3 0.0 2.8e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62768.1 - 1.7e-05 25.4 0.0 4.6e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG62768.1 - 0.0015 18.8 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG62769.1 - 4.3e-23 81.6 0.0 8.1e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62769.1 - 5.3e-20 71.3 0.0 1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG62769.1 - 2e-07 31.4 0.0 4.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62769.1 - 3.2e-05 24.5 0.0 7.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG62769.1 - 0.0027 18.0 0.0 0.0063 16.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Herpes_LMP1 PF05297.11 GBG62770.1 - 0.072 12.3 0.7 0.14 11.3 0.7 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ATG16 PF08614.11 GBG62770.1 - 0.11 12.7 2.2 0.18 12.0 2.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF659 PF04937.15 GBG62772.1 - 7.1e-08 32.4 0.0 2e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) WD40 PF00400.32 GBG62773.1 - 9.7e-38 127.5 13.5 1.2e-08 35.4 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG62773.1 - 2.3e-23 82.3 1.0 1.4e-05 25.3 0.0 5.2 4 1 1 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 GBG62773.1 - 8.5e-08 31.9 0.2 1.6e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 GBG62773.1 - 7.1e-05 22.8 3.3 0.55 10.1 0.2 3.2 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 GBG62773.1 - 0.0049 14.9 0.2 0.015 13.3 0.2 1.9 1 1 0 1 1 1 1 IKI3 family WD40_like PF17005.5 GBG62773.1 - 0.02 14.2 0.0 0.065 12.5 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain DSPc PF00782.20 GBG62774.1 - 5.9e-09 35.8 0.0 9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GBG62774.1 - 0.09 12.3 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Peptidase_C14 PF00656.22 GBG62774.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Caspase domain AnfG_VnfG PF03139.15 GBG62775.1 - 0.12 12.5 0.2 0.29 11.2 0.1 1.7 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit zf-BED PF02892.15 GBG62775.1 - 0.23 11.5 1.6 0.66 10.0 1.6 1.7 1 1 0 1 1 1 0 BED zinc finger DUF659 PF04937.15 GBG62776.1 - 2.1e-14 53.6 0.0 3.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG62777.1 - 6.2e-13 48.9 0.0 1.5e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG62777.1 - 9.4e-05 22.1 0.4 0.00021 21.0 0.4 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG62779.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG62779.1 - 0.00013 22.5 0.1 0.0003 21.3 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62779.1 - 0.004 17.8 0.1 0.01 16.5 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease ATE_N PF04376.13 GBG62779.1 - 0.013 15.9 0.1 0.03 14.7 0.1 1.6 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus Asp_protease PF09668.10 GBG62779.1 - 0.046 13.5 0.2 0.077 12.8 0.2 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG62779.1 - 0.048 13.4 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG62779.1 - 0.1 12.3 2.4 0.096 12.4 0.3 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG62780.1 - 1.8e-05 24.6 5.1 1.8e-05 24.6 5.1 2.1 2 0 0 2 2 2 1 Zinc knuckle Thioredoxin PF00085.20 GBG62782.1 - 2.4e-41 139.9 0.4 6.5e-27 93.5 0.1 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 GBG62782.1 - 2.2e-26 92.9 2.9 2.5e-18 66.6 2.4 3.3 2 2 2 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 GBG62782.1 - 1e-07 31.6 0.1 0.00033 20.1 0.0 3.4 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GBG62782.1 - 1.4e-07 31.9 0.1 9.2e-05 22.9 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG62782.1 - 1.9e-07 31.3 0.3 0.14 12.5 0.0 3.7 3 1 0 3 3 3 3 Thioredoxin-like Thioredoxin_7 PF13899.6 GBG62782.1 - 6.6e-06 26.2 0.1 0.0009 19.4 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like ERp29_N PF07912.13 GBG62782.1 - 0.00073 19.7 0.3 0.66 10.1 0.0 3.3 3 0 0 3 3 3 1 ERp29, N-terminal domain AhpC-TSA PF00578.21 GBG62782.1 - 0.0015 18.5 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 GBG62782.1 - 0.032 14.1 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 F plasmid transfer operon protein DUF659 PF04937.15 GBG62783.1 - 8.1e-11 42.0 0.0 1.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG62783.1 - 5e-05 23.0 0.0 9.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG62785.1 - 1.3e-22 79.7 0.0 2.7e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62785.1 - 1.7e-22 79.7 0.0 3.1e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG62785.1 - 0.0027 18.2 0.3 0.0093 16.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62785.1 - 0.003 18.2 0.0 0.0082 16.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Methyltransf_1N PF02870.15 GBG62786.1 - 0.00024 21.8 12.2 28 5.6 0.1 8.4 5 3 4 10 10 10 2 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain PapC_C PF13953.6 GBG62786.1 - 0.00069 19.4 59.3 1 9.2 0.6 12.6 1 1 13 15 15 15 10 PapC C-terminal domain DCR PF14047.6 GBG62786.1 - 1.6 9.0 15.9 47 4.3 0.1 7.9 4 2 9 13 13 13 0 Dppa2/4 conserved region ImpE PF07024.13 GBG62786.1 - 2.4 8.3 30.2 1 9.5 0.2 8.6 3 2 6 11 11 11 0 ImpE protein Methyltransf_1N PF02870.15 GBG62787.1 - 0.00032 21.4 13.2 50 4.8 0.0 8.3 4 4 4 8 8 8 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain PapC_C PF13953.6 GBG62787.1 - 0.00045 20.0 53.7 3.2 7.7 0.2 12.0 3 3 12 15 15 15 9 PapC C-terminal domain DCR PF14047.6 GBG62787.1 - 0.026 14.7 13.2 14 6.0 0.1 7.7 4 4 7 11 11 11 0 Dppa2/4 conserved region Toprim_N PF08275.11 GBG62787.1 - 0.09 12.8 12.3 2.4e+02 1.8 0.1 8.6 4 4 7 11 11 11 0 DNA primase catalytic core, N-terminal domain Histone PF00125.24 GBG62789.1 - 2e-24 86.4 2.2 3.6e-24 85.6 0.2 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Wtap PF17098.5 GBG62790.1 - 0.29 11.1 2.8 0.21 11.5 0.7 1.8 2 0 0 2 2 2 0 WTAP/Mum2p family Dishevelled PF02377.15 GBG62792.1 - 0.0054 17.2 0.8 0.0054 17.2 0.8 1.6 2 0 0 2 2 2 1 Dishevelled specific domain Asp_protease_2 PF13650.6 GBG62793.1 - 5.2e-08 33.4 0.0 9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62793.1 - 8.3e-08 32.7 0.0 1.6e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62793.1 - 1.9e-06 27.7 0.0 3.8e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62793.1 - 5.4e-06 26.2 0.0 8.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG62795.1 - 2.9e-06 27.0 0.3 4.8e-06 26.3 0.3 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MULE PF10551.9 GBG62797.1 - 1.9e-17 63.4 0.1 3.4e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG62797.1 - 1.1e-13 50.9 0.0 3.7e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 MuDR family transposase Transposase_mut PF00872.18 GBG62797.1 - 9.4e-06 24.7 0.1 1.6e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Transposase, Mutator family eIF2A PF08662.11 GBG62798.1 - 6.2e-68 228.5 0.4 5.1e-63 212.5 0.2 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 GBG62798.1 - 6.3e-10 38.7 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 GBG62798.1 - 4.5e-07 30.1 0.6 0.39 11.1 0.0 5.6 4 2 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Proteasom_Rpn13 PF04683.13 GBG62798.1 - 0.0051 17.3 0.3 0.46 11.1 0.0 3.7 3 1 0 3 3 3 1 Proteasome complex subunit Rpn13 ubiquitin receptor START PF01852.19 GBG62799.1 - 6.5e-09 35.5 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 START domain SepZ PF06066.11 GBG62799.1 - 0.14 12.3 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 SepZ TP2 PF01254.18 GBG62799.1 - 1.8 9.1 6.3 4.1 8.0 6.3 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 NOT2_3_5 PF04153.18 GBG62800.1 - 6.1e-32 110.4 3.4 6.1e-32 110.4 3.4 3.3 3 0 0 3 3 1 1 NOT2 / NOT3 / NOT5 family Spt20 PF12090.8 GBG62800.1 - 0.00043 20.0 81.6 0.0058 16.3 42.1 2.6 2 0 0 2 2 2 2 Spt20 family RNA_pol_Rpc4 PF05132.14 GBG62800.1 - 0.066 13.6 25.8 1.2 9.6 11.1 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Exonuc_VII_L PF02601.15 GBG62800.1 - 0.11 12.1 29.3 0.18 11.3 14.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit PNISR PF15996.5 GBG62800.1 - 0.13 12.6 32.1 0.22 11.8 13.1 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR RR_TM4-6 PF06459.12 GBG62800.1 - 0.15 11.9 30.4 0.62 9.8 13.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 GBG62800.1 - 0.22 11.7 34.4 1.2 9.2 18.2 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Suf PF05843.14 GBG62800.1 - 0.32 10.9 38.2 1.8 8.5 12.8 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Raftlin PF15250.6 GBG62800.1 - 0.35 9.6 21.1 0.27 9.9 5.9 2.1 2 0 0 2 2 2 0 Raftlin NPR3 PF03666.13 GBG62800.1 - 0.57 8.9 26.3 0.16 10.7 9.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 GBG62800.1 - 0.58 9.9 26.3 1.8 8.3 11.9 2.1 2 0 0 2 2 2 0 AAA domain Tim54 PF11711.8 GBG62800.1 - 1.2 7.9 26.5 1.1 8.0 11.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF719 PF05334.13 GBG62800.1 - 1.5 9.0 26.9 4.7 7.4 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) CPSF100_C PF13299.6 GBG62800.1 - 1.7 8.8 29.7 0.75 10.0 6.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SprA-related PF12118.8 GBG62800.1 - 2.1 7.4 60.0 0.074 12.2 17.7 2.5 2 0 0 2 2 2 0 SprA-related family CSRNP_N PF16019.5 GBG62800.1 - 2.5 8.0 33.0 2 8.3 14.2 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus AAR2 PF05282.11 GBG62800.1 - 2.6 7.4 17.2 1.3 8.3 4.3 2.2 2 0 0 2 2 2 0 AAR2 protein Piezo_RRas_bdg PF12166.8 GBG62800.1 - 2.6 7.2 15.1 4.3 6.5 15.1 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain DUF5523 PF17661.1 GBG62800.1 - 3.4 7.3 34.2 5.7 6.5 16.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) EIIBC-GUT_N PF03612.14 GBG62800.1 - 3.4 7.4 27.9 0.64 9.7 4.9 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Pkinase_fungal PF17667.1 GBG62800.1 - 3.5 6.3 16.2 1.1 8.0 5.5 2.1 2 0 0 2 2 2 0 Fungal protein kinase EOS1 PF12326.8 GBG62800.1 - 3.9 7.4 19.6 2.3 8.1 5.8 2.2 2 0 0 2 2 2 0 N-glycosylation protein DUF4366 PF14283.6 GBG62800.1 - 5.2 7.1 13.7 2.5 8.2 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) GREB1 PF15782.5 GBG62800.1 - 6.5 3.7 31.8 10 3.1 31.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCDC53 PF10152.9 GBG62800.1 - 6.7 7.1 37.0 6.1 7.2 10.0 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TCP PF03634.13 GBG62800.1 - 8.8 6.9 33.9 8.4 6.9 9.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor NOT2_3_5 PF04153.18 GBG62801.1 - 6.1e-32 110.4 3.4 6.1e-32 110.4 3.4 3.3 3 0 0 3 3 1 1 NOT2 / NOT3 / NOT5 family Spt20 PF12090.8 GBG62801.1 - 0.00022 20.9 80.7 0.0058 16.3 42.1 2.6 2 0 0 2 2 2 2 Spt20 family RNA_pol_Rpc4 PF05132.14 GBG62801.1 - 0.066 13.6 25.8 1.2 9.6 11.1 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 PNISR PF15996.5 GBG62801.1 - 0.11 12.8 31.9 0.22 11.8 13.1 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Exonuc_VII_L PF02601.15 GBG62801.1 - 0.12 11.9 29.5 0.18 11.3 14.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit CCSAP PF15748.5 GBG62801.1 - 0.22 11.7 34.4 1.2 9.2 18.2 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 GBG62801.1 - 0.32 10.8 31.5 0.62 9.8 13.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 GBG62801.1 - 0.32 10.9 38.3 1.8 8.5 13.0 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) NPR3 PF03666.13 GBG62801.1 - 0.56 8.9 26.3 0.16 10.7 9.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 GBG62801.1 - 0.58 9.9 26.3 1.8 8.3 11.9 2.1 2 0 0 2 2 2 0 AAA domain Tim54 PF11711.8 GBG62801.1 - 1.2 7.9 26.5 1.1 8.0 11.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 GBG62801.1 - 1.7 8.8 29.7 0.75 10.0 6.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Rxt3 PF08642.10 GBG62801.1 - 1.8 9.3 18.0 4 8.2 2.6 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF719 PF05334.13 GBG62801.1 - 1.8 8.7 27.2 5.7 7.1 13.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Piezo_RRas_bdg PF12166.8 GBG62801.1 - 2.2 7.5 14.8 3.6 6.8 14.8 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain AAR2 PF05282.11 GBG62801.1 - 2.4 7.5 17.1 1.3 8.3 4.3 2.2 2 0 0 2 2 2 0 AAR2 protein CSRNP_N PF16019.5 GBG62801.1 - 2.5 8.0 33.0 2 8.3 14.2 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Pkinase_fungal PF17667.1 GBG62801.1 - 3.4 6.3 16.2 1.1 8.0 5.5 2.1 2 0 0 2 2 2 0 Fungal protein kinase DUF5523 PF17661.1 GBG62801.1 - 3.7 7.2 34.4 5.7 6.5 16.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) EOS1 PF12326.8 GBG62801.1 - 3.7 7.4 19.6 2.3 8.1 5.8 2.2 2 0 0 2 2 2 0 N-glycosylation protein SprA-related PF12118.8 GBG62801.1 - 3.7 6.6 60.5 0.13 11.4 18.3 2.5 2 0 0 2 2 2 0 SprA-related family CCDC53 PF10152.9 GBG62801.1 - 4.4 7.7 36.5 4 7.8 9.4 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex EIIBC-GUT_N PF03612.14 GBG62801.1 - 5.1 6.8 28.5 0.93 9.2 5.5 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4366 PF14283.6 GBG62801.1 - 5.2 7.1 13.7 2.5 8.2 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) GREB1 PF15782.5 GBG62801.1 - 8.4 3.4 32.2 13 2.7 32.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TCP PF03634.13 GBG62801.1 - 8.5 6.9 33.8 8.1 7.0 9.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor NOT2_3_5 PF04153.18 GBG62802.1 - 6.1e-32 110.5 3.4 6.1e-32 110.5 3.4 3.3 3 0 0 3 3 1 1 NOT2 / NOT3 / NOT5 family Spt20 PF12090.8 GBG62802.1 - 0.00043 20.0 81.6 0.0058 16.3 42.1 2.6 2 0 0 2 2 2 2 Spt20 family RNA_pol_Rpc4 PF05132.14 GBG62802.1 - 0.066 13.7 25.8 1.2 9.6 11.1 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Exonuc_VII_L PF02601.15 GBG62802.1 - 0.11 12.1 29.3 0.18 11.3 14.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit PNISR PF15996.5 GBG62802.1 - 0.13 12.6 32.1 0.22 11.8 13.1 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR RR_TM4-6 PF06459.12 GBG62802.1 - 0.15 11.9 30.4 0.62 9.8 13.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 GBG62802.1 - 0.22 11.7 34.4 1.2 9.2 18.2 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Suf PF05843.14 GBG62802.1 - 0.32 10.9 38.2 1.8 8.5 12.8 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Raftlin PF15250.6 GBG62802.1 - 0.35 9.6 21.1 0.27 9.9 5.9 2.1 2 0 0 2 2 2 0 Raftlin NPR3 PF03666.13 GBG62802.1 - 0.56 8.9 26.3 0.16 10.7 9.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 GBG62802.1 - 0.58 9.9 26.3 1.8 8.3 11.9 2.1 2 0 0 2 2 2 0 AAA domain Tim54 PF11711.8 GBG62802.1 - 1.2 7.9 26.5 1.1 8.0 11.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF719 PF05334.13 GBG62802.1 - 1.5 9.0 26.9 4.7 7.4 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) CPSF100_C PF13299.6 GBG62802.1 - 1.7 8.8 29.7 0.75 10.0 6.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SprA-related PF12118.8 GBG62802.1 - 2.1 7.4 60.0 0.074 12.2 17.7 2.5 2 0 0 2 2 2 0 SprA-related family CSRNP_N PF16019.5 GBG62802.1 - 2.5 8.0 33.0 2 8.3 14.2 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus AAR2 PF05282.11 GBG62802.1 - 2.6 7.4 17.2 1.3 8.3 4.3 2.2 2 0 0 2 2 2 0 AAR2 protein Piezo_RRas_bdg PF12166.8 GBG62802.1 - 2.6 7.2 15.1 4.3 6.5 15.1 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain DUF5523 PF17661.1 GBG62802.1 - 3.4 7.3 34.2 5.7 6.5 16.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) EIIBC-GUT_N PF03612.14 GBG62802.1 - 3.4 7.4 27.9 0.64 9.7 4.9 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Pkinase_fungal PF17667.1 GBG62802.1 - 3.5 6.3 16.2 1.1 8.0 5.5 2.1 2 0 0 2 2 2 0 Fungal protein kinase EOS1 PF12326.8 GBG62802.1 - 3.9 7.4 19.6 2.3 8.1 5.8 2.2 2 0 0 2 2 2 0 N-glycosylation protein DUF4366 PF14283.6 GBG62802.1 - 5.2 7.1 13.7 2.5 8.2 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) GREB1 PF15782.5 GBG62802.1 - 6.5 3.7 31.8 10 3.1 31.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCDC53 PF10152.9 GBG62802.1 - 6.7 7.1 37.0 6.1 7.3 10.0 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TCP PF03634.13 GBG62802.1 - 8.8 6.9 33.9 8.4 6.9 9.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor NOT2_3_5 PF04153.18 GBG62803.1 - 6.2e-32 110.4 3.4 6.2e-32 110.4 3.4 3.3 3 0 0 3 3 1 1 NOT2 / NOT3 / NOT5 family Spt20 PF12090.8 GBG62803.1 - 0.00023 20.9 80.7 0.0058 16.3 42.1 2.6 2 0 0 2 2 2 2 Spt20 family RNA_pol_Rpc4 PF05132.14 GBG62803.1 - 0.069 13.6 25.8 1.2 9.6 11.1 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Exonuc_VII_L PF02601.15 GBG62803.1 - 0.11 12.1 29.3 0.19 11.3 14.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit PNISR PF15996.5 GBG62803.1 - 0.13 12.5 32.1 0.22 11.7 13.1 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR RR_TM4-6 PF06459.12 GBG62803.1 - 0.15 11.9 30.4 0.63 9.8 13.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 GBG62803.1 - 0.22 11.6 34.4 1.2 9.2 18.2 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Suf PF05843.14 GBG62803.1 - 0.32 10.9 38.2 1.8 8.5 12.8 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) NPR3 PF03666.13 GBG62803.1 - 0.57 8.9 26.3 0.16 10.7 9.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 GBG62803.1 - 0.59 9.9 26.3 1.8 8.3 11.9 2.1 2 0 0 2 2 2 0 AAA domain Tim54 PF11711.8 GBG62803.1 - 0.99 8.1 26.5 1.1 7.9 11.1 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF719 PF05334.13 GBG62803.1 - 1.5 9.0 26.9 4.8 7.3 5.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) CPSF100_C PF13299.6 GBG62803.1 - 1.7 8.8 29.7 0.76 9.9 6.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SprA-related PF12118.8 GBG62803.1 - 2.1 7.4 60.0 0.074 12.2 17.7 2.5 2 0 0 2 2 2 0 SprA-related family CSRNP_N PF16019.5 GBG62803.1 - 2.5 7.9 33.0 2 8.3 14.2 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus AAR2 PF05282.11 GBG62803.1 - 2.6 7.3 17.2 1.3 8.3 4.3 2.2 2 0 0 2 2 2 0 AAR2 protein DUF5523 PF17661.1 GBG62803.1 - 3.4 7.3 34.2 5.7 6.5 16.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) EIIBC-GUT_N PF03612.14 GBG62803.1 - 3.5 7.3 27.9 0.64 9.7 4.9 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Pkinase_fungal PF17667.1 GBG62803.1 - 3.5 6.3 16.2 1.1 8.0 5.5 2.1 2 0 0 2 2 2 0 Fungal protein kinase Piezo_RRas_bdg PF12166.8 GBG62803.1 - 3.6 6.8 15.6 6.1 6.0 15.6 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain EOS1 PF12326.8 GBG62803.1 - 4 7.3 19.6 2.3 8.1 5.8 2.2 2 0 0 2 2 2 0 N-glycosylation protein DUF4366 PF14283.6 GBG62803.1 - 5.3 7.1 13.7 2.5 8.1 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) GREB1 PF15782.5 GBG62803.1 - 6.5 3.7 31.8 10 3.0 31.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCDC53 PF10152.9 GBG62803.1 - 6.9 7.1 37.0 6.1 7.2 10.0 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TCP PF03634.13 GBG62803.1 - 8.9 6.9 33.9 8.4 6.9 9.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor Rab3-GTPase_cat PF13890.6 GBG62804.1 - 2e-51 173.8 3.1 2.2e-35 121.7 0.1 2.4 2 0 0 2 2 2 2 Rab3 GTPase-activating protein catalytic subunit Rab3-GTPase_cat PF13890.6 GBG62806.1 - 2e-51 173.8 3.1 2.2e-35 121.7 0.1 2.4 2 0 0 2 2 2 2 Rab3 GTPase-activating protein catalytic subunit Rab3-GTPase_cat PF13890.6 GBG62807.1 - 2.1e-51 173.8 3.1 2.2e-35 121.7 0.1 2.4 2 0 0 2 2 2 2 Rab3 GTPase-activating protein catalytic subunit Arg_repressor PF01316.21 GBG62808.1 - 0.064 13.0 0.7 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain Myb_DNA-bind_4 PF13837.6 GBG62809.1 - 2.5e-07 31.0 0.7 4.7e-07 30.1 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG62809.1 - 0.028 14.6 0.3 0.06 13.5 0.3 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG62809.1 - 0.036 14.4 0.7 0.071 13.4 0.7 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG62809.1 - 0.14 12.2 0.8 0.34 11.0 0.8 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG62809.1 - 0.26 11.6 1.5 0.59 10.4 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain PIF1 PF05970.14 GBG62810.1 - 8.3e-95 318.0 0.0 1e-94 317.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 GBG62810.1 - 1.6e-07 31.2 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 GBG62810.1 - 0.0011 17.0 0.0 0.002 16.2 0.0 1.3 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.6 GBG62810.1 - 0.006 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 GBG62810.1 - 0.08 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RT_RNaseH_2 PF17919.1 GBG62811.1 - 2.9e-33 113.9 0.1 4.9e-33 113.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62811.1 - 1.1e-30 106.0 0.1 2.1e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62811.1 - 2.1e-21 76.5 0.6 4.2e-20 72.2 0.6 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG62812.1 - 1.6e-41 141.7 0.0 3.7e-41 140.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG62812.1 - 0.026 14.4 3.3 0.026 14.4 3.3 3.5 3 0 0 3 3 3 0 AT hook motif XRCC4 PF06632.12 GBG62813.1 - 0.041 12.7 10.3 0.046 12.6 10.3 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 REV PF00424.18 GBG62813.1 - 0.044 13.8 0.6 0.062 13.3 0.5 1.4 1 1 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Nop53 PF07767.11 GBG62813.1 - 0.12 11.8 18.0 0.12 11.7 18.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM76 PF16046.5 GBG62813.1 - 0.31 10.4 9.4 0.38 10.1 9.4 1.2 1 0 0 1 1 1 0 FAM76 protein PA26 PF04636.13 GBG62813.1 - 0.69 8.8 10.6 0.71 8.7 10.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF5595 PF18077.1 GBG62813.1 - 0.95 9.6 8.6 1.9 8.6 7.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) Herpes_UL25 PF01499.16 GBG62813.1 - 1.9 6.9 7.9 2 6.9 7.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF1943 PF09172.11 GBG62813.1 - 2.7 7.1 5.6 3.3 6.9 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF4407 PF14362.6 GBG62813.1 - 3.3 7.0 9.7 3.5 6.9 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Radial_spoke_3 PF06098.11 GBG62813.1 - 6.3 6.0 20.4 7.9 5.7 20.4 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 TMPIT PF07851.13 GBG62813.1 - 9.2 5.4 10.1 11 5.2 10.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF2271 PF10029.9 GBG62814.1 - 0.012 15.3 0.1 0.031 13.9 0.1 1.8 1 1 0 1 1 1 0 Predicted periplasmic protein (DUF2271) SDA1 PF05285.12 GBG62814.1 - 0.077 12.4 3.7 0.091 12.2 3.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2981 PF11200.8 GBG62814.1 - 1.9 8.2 8.9 2.3 7.9 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Mucin PF01456.17 GBG62814.1 - 2.8 7.9 21.6 4.6 7.2 21.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Menin PF05053.13 GBG62814.1 - 6.8 4.9 10.8 9.7 4.4 10.8 1.3 1 0 0 1 1 1 0 Menin BSP_II PF05432.11 GBG62814.1 - 8.1 6.1 24.3 12 5.5 24.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MFS_1 PF07690.16 GBG62817.1 - 6.4e-32 110.8 26.9 9.9e-32 110.2 25.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GBG62817.1 - 6.5e-05 22.0 6.8 0.065 12.1 5.1 2.4 2 1 0 2 2 2 2 MFS_1 like family OATP PF03137.20 GBG62817.1 - 0.011 14.1 8.0 0.19 10.0 3.4 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EMP70 PF02990.16 GBG62817.1 - 0.56 8.8 3.8 0.2 10.3 0.3 2.0 2 0 0 2 2 2 0 Endomembrane protein 70 MMS1_N PF10433.9 GBG62818.1 - 9e-153 509.4 0.0 4.2e-121 405.0 0.0 2.4 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GBG62818.1 - 1.4e-95 320.3 0.0 4.9e-94 315.3 0.0 2.5 2 0 0 2 2 2 1 CPSF A subunit region RVT_1 PF00078.27 GBG62818.1 - 1.5e-25 90.1 0.2 3.1e-25 89.0 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62818.1 - 2.1e-19 69.7 0.1 7.8e-19 67.9 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62818.1 - 2.1e-12 46.9 0.0 5.4e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG62818.1 - 0.033 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG62819.1 - 2.3e-29 101.8 0.1 5.3e-29 100.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62819.1 - 4.6e-29 100.4 0.0 1.2e-28 99.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BK_channel_a PF03493.18 GBG62819.1 - 1.1e-19 70.4 0.0 3.5e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 GBG62819.1 - 4.5e-09 36.1 0.0 8.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Ion channel RVT_1 PF00078.27 GBG62819.1 - 3.7e-07 29.9 0.1 6.5e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_lysozyme PF00959.19 GBG62820.1 - 0.17 12.3 1.4 0.66 10.4 0.0 2.6 3 0 0 3 3 3 0 Phage lysozyme RVT_1 PF00078.27 GBG62821.1 - 6.2e-33 114.2 0.0 9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_3 PF12776.7 GBG62822.1 - 0.022 15.7 0.6 0.03 15.3 0.6 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain APOC4 PF15119.6 GBG62822.1 - 0.074 13.3 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein C4 DUF659 PF04937.15 GBG62824.1 - 9.5e-11 41.8 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG62825.1 - 1.2e-15 57.7 0.0 2.2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG62825.1 - 1e-07 31.9 0.2 2.2e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG62825.1 - 0.00043 20.4 0.1 0.00085 19.5 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger TFIIF_alpha PF05793.12 GBG62825.1 - 0.67 8.5 39.4 1.2 7.6 39.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mpp10 PF04006.12 GBG62825.1 - 0.98 7.8 41.3 1.7 7.0 41.3 1.4 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 GBG62825.1 - 3.9 6.7 47.6 6.6 6.0 47.6 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG62825.1 - 4.3 5.4 48.4 7.1 4.7 48.4 1.2 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG62825.1 - 5.8 6.4 23.0 11 5.5 23.0 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Plasmodium_Vir PF05795.11 GBG62825.1 - 6 6.2 13.2 9.5 5.5 13.2 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RVT_1 PF00078.27 GBG62826.1 - 1.4e-56 191.5 1.3 1.5e-27 96.6 0.2 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62826.1 - 6.3e-15 55.0 0.2 1.6e-14 53.7 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG62826.1 - 3.6e-05 23.9 0.1 0.00014 22.0 0.1 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG62826.1 - 0.00013 22.2 1.9 0.023 15.0 0.0 3.9 3 0 0 3 3 3 1 Retrotransposon gag protein rve PF00665.26 GBG62826.1 - 0.00055 20.1 0.0 0.0037 17.4 0.0 2.6 1 0 0 1 1 1 1 Integrase core domain Lys-AminoMut_A PF09043.11 GBG62826.1 - 0.051 12.0 0.3 0.12 10.8 0.3 1.5 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Trans_reg_C PF00486.28 GBG62826.1 - 0.18 11.9 1.8 8.8 6.5 0.2 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal CLZ PF16526.5 GBG62826.1 - 0.85 10.0 6.0 0.47 10.8 0.5 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pox_Rap94 PF03294.14 GBG62827.1 - 0.22 9.6 0.0 0.29 9.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 RVT_1 PF00078.27 GBG62828.1 - 1.8e-35 122.5 0.0 3.4e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62828.1 - 7.1e-30 103.0 0.0 2.1e-29 101.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62828.1 - 8.1e-30 103.2 0.1 2.5e-29 101.6 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62828.1 - 1.1e-17 63.8 0.4 2.7e-17 62.6 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62828.1 - 0.0003 21.0 0.1 0.00086 19.5 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG62828.1 - 0.0039 17.4 0.1 0.011 15.9 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger OSTbeta PF15048.6 GBG62828.1 - 0.014 15.6 3.4 0.039 14.1 3.4 1.7 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Phage_GPO PF05929.11 GBG62828.1 - 0.17 11.5 0.1 0.17 11.5 0.1 3.3 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase ADP_ribosyl_GH PF03747.14 GBG62828.1 - 0.37 10.5 1.0 21 4.7 0.0 3.6 4 0 0 4 4 4 0 ADP-ribosylglycohydrolase DUF4446 PF14584.6 GBG62828.1 - 8.1 6.4 8.1 1.5 8.8 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) BK_channel_a PF03493.18 GBG62829.1 - 2e-20 72.8 0.0 6.3e-20 71.2 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 GBG62829.1 - 9.2e-12 44.7 16.5 1.6e-11 43.9 16.5 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 GBG62829.1 - 2.7e-07 30.5 9.0 2.7e-07 30.5 9.0 2.5 2 1 1 3 3 3 1 Ion channel Lig_chan PF00060.26 GBG62829.1 - 0.0012 18.7 1.5 0.0026 17.6 1.5 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel RVT_1 PF00078.27 GBG62830.1 - 8e-34 117.1 0.0 1.4e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62830.1 - 3.7e-30 103.9 0.0 1.2e-29 102.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62830.1 - 2.2e-29 101.8 0.0 5.9e-29 100.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG62830.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4392 PF14336.6 GBG62830.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Peripla_BP_2 PF01497.18 GBG62831.1 - 1.5e-16 60.7 0.0 1.7e-15 57.3 0.0 2.9 1 1 0 1 1 1 1 Periplasmic binding protein zf-CCHC PF00098.23 GBG62832.1 - 0.054 13.6 0.5 0.1 12.7 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle tRNA-Thr_ED PF08915.11 GBG62832.1 - 4.4 7.4 6.3 0.32 11.1 0.3 2.1 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase GATase_3 PF07685.14 GBG62833.1 - 2.6e-32 112.0 0.0 4.4e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AAA_26 PF13500.6 GBG62833.1 - 7e-07 29.3 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2163 PF09931.9 GBG62833.1 - 6.6e-06 26.4 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2163) CbiA PF01656.23 GBG62833.1 - 2.8e-05 24.2 0.0 4.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DJ-1_PfpI PF01965.24 GBG62833.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family SelP_N PF04592.14 GBG62833.1 - 8.4 5.7 23.8 15 4.9 23.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FeoA PF04023.14 GBG62834.1 - 0.0083 16.4 0.1 0.019 15.2 0.1 1.6 1 0 0 1 1 1 1 FeoA domain SAM_KSR1 PF13543.6 GBG62834.1 - 0.023 14.8 0.7 0.73 10.0 0.0 2.5 2 1 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 DUF3287 PF11690.8 GBG62834.1 - 0.055 13.2 1.3 0.19 11.5 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Cob_adeno_trans PF01923.18 GBG62834.1 - 1.9 8.6 5.7 16 5.6 0.1 3.0 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Nodulin-like PF06813.13 GBG62835.1 - 1.7e-44 152.2 13.5 1.7e-44 152.2 13.5 1.9 3 0 0 3 3 3 1 Nodulin-like MFS_1 PF07690.16 GBG62835.1 - 1.2e-10 40.9 33.6 3.1e-08 32.9 2.6 3.9 2 2 2 4 4 4 3 Major Facilitator Superfamily CAP_N PF01213.19 GBG62835.1 - 0.17 11.3 2.3 0.3 10.5 2.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RT_RNaseH PF17917.1 GBG62836.1 - 1.1e-28 99.6 0.2 2.2e-28 98.6 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62836.1 - 5.6e-27 93.7 0.0 1.2e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG62836.1 - 1.5e-26 93.1 0.3 4.9e-26 91.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG62836.1 - 3.6e-16 59.0 0.1 8.4e-16 57.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62836.1 - 6.8e-15 55.3 0.0 3.7e-14 52.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain DUF1564 PF07600.11 GBG62836.1 - 0.0025 17.5 0.2 0.0065 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Pirin PF02678.16 GBG62837.1 - 2.4e-32 111.1 0.2 3.9e-32 110.5 0.2 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 GBG62837.1 - 7.3e-32 109.8 0.0 4.1e-29 101.0 0.0 2.9 3 0 0 3 3 3 2 Pirin C-terminal cupin domain Cupin_2 PF07883.11 GBG62837.1 - 5.6e-05 22.8 1.4 0.041 13.6 0.7 2.5 2 0 0 2 2 2 2 Cupin domain AAA PF00004.29 GBG62840.1 - 7.6e-41 139.6 0.0 1.6e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 GBG62840.1 - 2.2e-15 57.0 0.0 8.2e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 GBG62840.1 - 1.3e-09 37.7 0.0 4.5e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GBG62840.1 - 4.5e-06 26.7 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG62840.1 - 0.00035 20.4 0.0 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 GBG62840.1 - 0.0013 18.2 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 GBG62840.1 - 0.0017 17.6 0.1 0.0032 16.7 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 GBG62840.1 - 0.004 17.4 0.0 1.4 9.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG62840.1 - 0.016 15.6 0.1 0.016 15.6 0.1 3.6 2 2 0 2 2 1 0 AAA ATPase domain AAA_17 PF13207.6 GBG62840.1 - 0.041 14.3 0.0 0.041 14.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 GBG62840.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 GBG62840.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsH_ext PF06480.15 GBG62840.1 - 0.18 12.2 0.0 0.88 10.0 0.0 2.1 2 0 0 2 2 2 0 FtsH Extracellular AAA_18 PF13238.6 GBG62840.1 - 0.24 11.9 0.0 0.24 11.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain RT_RNaseH_2 PF17919.1 GBG62841.1 - 9.9e-28 96.1 0.0 1.8e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62841.1 - 2.5e-25 88.8 0.0 4.5e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62841.1 - 1.8e-15 57.1 0.1 3.3e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG62841.1 - 1.2e-05 25.1 3.2 2.6e-05 24.1 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG62841.1 - 0.0042 16.9 0.1 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GBG62841.1 - 0.027 14.3 4.1 0.051 13.4 4.1 1.5 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.14 GBG62841.1 - 1.2 7.4 23.4 1.9 6.7 23.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG62842.1 - 5.8e-35 119.3 0.0 1.1e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62842.1 - 7.6e-31 106.5 0.2 1.9e-30 105.3 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62842.1 - 3.9e-11 42.9 0.0 1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62842.1 - 0.0019 18.4 0.1 0.032 14.4 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG62843.1 - 0.0073 16.3 0.7 0.014 15.3 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle MID_MedPIWI PF18296.1 GBG62843.1 - 0.09 12.6 0.6 0.19 11.5 0.3 1.4 1 1 0 1 1 1 0 MID domain of medPIWI Mannitol_dh_C PF08125.13 GBG62843.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain zf-CCHC PF00098.23 GBG62843.1 - 0.24 11.6 3.8 0.36 11.0 3.8 1.3 1 0 0 1 1 1 0 Zinc knuckle tRNA-synt_2c PF01411.19 GBG62844.1 - 1.3e-106 357.4 0.0 2.1e-66 224.6 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (A) RVT_1 PF00078.27 GBG62844.1 - 1.3e-29 103.3 0.1 3e-29 102.1 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62844.1 - 2.4e-23 82.1 0.0 6.1e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DHHA1 PF02272.19 GBG62844.1 - 1.1e-22 80.9 0.4 8.1e-22 78.1 1.2 2.1 2 0 0 2 2 2 1 DHHA1 domain RT_RNaseH PF17917.1 GBG62844.1 - 1.4e-21 76.7 0.0 3.3e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62844.1 - 2.4e-20 72.4 0.1 5.2e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain tRNA_SAD PF07973.14 GBG62844.1 - 2.5e-16 59.5 0.8 5e-16 58.5 0.8 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RVP_2 PF08284.11 GBG62844.1 - 1.2e-08 34.8 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62844.1 - 1.7e-08 35.0 0.0 4.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG62844.1 - 9.8e-06 25.8 0.0 2.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG62844.1 - 1e-05 26.0 0.0 2.8e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG62844.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG62844.1 - 0.016 15.5 0.0 0.062 13.6 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein tRNA-synt_2c PF01411.19 GBG62845.1 - 1e-153 512.8 0.0 2.2e-66 224.5 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetases class II (A) RVT_1 PF00078.27 GBG62845.1 - 1.3e-29 103.3 0.1 3.2e-29 102.1 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62845.1 - 2.5e-23 82.0 0.0 6.3e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DHHA1 PF02272.19 GBG62845.1 - 1.2e-22 80.8 0.4 8.5e-22 78.1 1.2 2.1 2 0 0 2 2 2 1 DHHA1 domain RT_RNaseH PF17917.1 GBG62845.1 - 1.4e-21 76.7 0.0 3.4e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62845.1 - 2.6e-20 72.3 0.1 5.4e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain tRNA_SAD PF07973.14 GBG62845.1 - 2.6e-16 59.4 0.8 5.2e-16 58.5 0.8 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RVP_2 PF08284.11 GBG62845.1 - 1.3e-08 34.7 0.0 2.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62845.1 - 1.8e-08 34.9 0.0 4.8e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG62845.1 - 1e-05 25.7 0.0 2.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG62845.1 - 1.1e-05 25.9 0.0 2.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG62845.1 - 0.0024 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG62845.1 - 0.017 15.4 0.0 0.065 13.5 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein tRNA-synt_2c PF01411.19 GBG62846.1 - 4.1e-161 537.2 0.0 5.5e-93 312.4 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (A) RVT_1 PF00078.27 GBG62846.1 - 1.2e-29 103.4 0.1 2.9e-29 102.2 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62846.1 - 2.3e-23 82.1 0.0 5.9e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DHHA1 PF02272.19 GBG62846.1 - 1e-22 81.1 0.3 7.9e-22 78.2 1.2 2.1 2 0 0 2 2 2 1 DHHA1 domain RT_RNaseH PF17917.1 GBG62846.1 - 1.3e-21 76.8 0.0 3.2e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62846.1 - 2.5e-20 72.3 0.1 5.1e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain tRNA_SAD PF07973.14 GBG62846.1 - 2.5e-16 59.5 0.8 4.9e-16 58.6 0.8 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RVP_2 PF08284.11 GBG62846.1 - 1.2e-08 34.9 0.0 2.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62846.1 - 1.6e-08 35.0 0.0 4.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG62846.1 - 9.8e-06 25.8 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG62846.1 - 1e-05 26.0 0.0 2.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG62846.1 - 0.0022 17.8 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG62846.1 - 0.015 15.5 0.0 0.06 13.6 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein DUF659 PF04937.15 GBG62849.1 - 2e-32 112.2 0.2 3.2e-32 111.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Histone_H2A_C PF16211.5 GBG62850.1 - 8.7e-19 67.0 1.0 1.4e-18 66.3 1.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GBG62850.1 - 9.2e-15 55.2 0.0 1.3e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG62850.1 - 0.00017 21.8 0.0 0.00025 21.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribul_P_3_epim PF00834.19 GBG62851.1 - 2e-25 89.3 0.1 2.4e-25 89.1 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family rve PF00665.26 GBG62853.1 - 8.5e-05 22.7 0.1 0.00024 21.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG62853.1 - 0.0014 18.5 0.6 0.0033 17.3 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF2390 PF09523.10 GBG62853.1 - 7.9 6.9 9.5 0.17 12.3 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) PIN_5 PF08745.11 GBG62854.1 - 0.05 13.0 0.3 0.073 12.5 0.3 1.2 1 0 0 1 1 1 0 PINc domain ribonuclease RVT_1 PF00078.27 GBG62855.1 - 1.2e-29 103.5 0.1 9.4e-29 100.5 0.1 2.4 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62855.1 - 2.7e-25 88.3 0.0 7.9e-25 86.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62855.1 - 2e-24 85.9 0.0 7.2e-24 84.1 0.0 2.1 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62855.1 - 8e-19 67.5 0.2 2e-18 66.2 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG62855.1 - 9.6e-07 29.4 0.0 2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG62855.1 - 1.9e-06 28.1 0.0 9.1e-05 22.6 0.0 2.8 1 1 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG62855.1 - 0.00018 21.3 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG62855.1 - 0.00018 22.0 0.0 0.00041 20.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG62855.1 - 0.0016 18.7 6.3 0.01 16.1 0.1 4.2 3 0 0 3 3 3 1 Retrotransposon gag protein SPACA9 PF15120.6 GBG62855.1 - 0.0062 16.3 0.8 0.015 15.0 0.8 1.7 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 Asp_protease PF09668.10 GBG62855.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Spc24 PF08286.11 GBG62855.1 - 0.56 10.5 3.0 5.3 7.3 1.2 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 BLOC1_2 PF10046.9 GBG62855.1 - 2.7 8.4 8.1 0.62 10.4 2.4 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 GBG62855.1 - 3.8 8.2 9.6 3.1 8.5 4.1 3.6 3 0 0 3 3 3 0 SlyX RVT_1 PF00078.27 GBG62856.1 - 1e-34 120.0 0.1 1.8e-34 119.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62856.1 - 1.3e-27 96.2 0.1 3.5e-27 94.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62856.1 - 3e-19 68.9 0.0 1.2e-18 66.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG62856.1 - 0.11 12.2 0.1 0.11 12.2 0.1 3.1 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase LAP1C PF05609.12 GBG62856.1 - 6.3 5.8 18.0 9.7 5.2 18.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RVT_1 PF00078.27 GBG62857.1 - 7.8e-24 84.4 0.1 1.3e-23 83.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62857.1 - 2.1e-16 59.7 0.1 5.3e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62857.1 - 1.2e-10 41.7 0.0 3.5e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG62857.1 - 1.5e-09 37.7 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG62857.1 - 0.00049 20.3 0.0 0.00049 20.3 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG62857.1 - 0.0028 17.9 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62858.1 - 7e-19 67.7 0.1 1.6e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62858.1 - 1.7e-17 63.7 0.0 4.3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG62858.1 - 0.00056 20.1 0.0 0.002 18.3 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG62858.1 - 0.022 15.0 0.0 0.085 13.1 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein NIR_SIR PF01077.22 GBG62858.1 - 0.12 11.9 0.2 0.23 10.9 0.2 1.5 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain G8 PF10162.9 GBG62859.1 - 2.7e-26 92.0 0.0 9.3e-22 77.4 0.0 2.8 2 0 0 2 2 2 2 G8 domain Rho_N PF07498.12 GBG62859.1 - 0.0054 16.6 0.2 0.012 15.5 0.2 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 GBG62859.1 - 0.023 14.4 1.2 0.032 14.0 0.0 1.9 2 0 0 2 2 2 0 SAP domain Integrase_H2C2 PF17921.1 GBG62860.1 - 2.8e-17 62.6 0.1 5e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62860.1 - 2.8e-12 46.9 0.3 8.5e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG62860.1 - 0.044 14.0 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG62860.1 - 0.08 12.9 0.0 0.8 9.7 0.0 2.4 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG62860.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) K_channel_TID PF07941.11 GBG62860.1 - 8.9 6.8 11.5 22 5.6 11.5 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DASH_Dad4 PF08650.10 GBG62861.1 - 0.055 13.4 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad4 Filament PF00038.21 GBG62861.1 - 0.095 12.3 13.1 0.078 12.5 6.0 2.2 2 0 0 2 2 2 0 Intermediate filament protein SpoOE-like PF09388.10 GBG62861.1 - 0.29 11.0 6.9 4.2 7.3 0.9 3.7 4 0 0 4 4 4 0 Spo0E like sporulation regulatory protein LPP PF04728.13 GBG62861.1 - 0.37 11.2 3.6 7.6 7.0 0.2 3.6 4 0 0 4 4 3 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 GBG62861.1 - 1.2 8.4 14.3 1.1 8.5 4.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 GBG62861.1 - 1.2 7.9 16.0 0.34 9.7 1.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein FlxA PF14282.6 GBG62861.1 - 1.8 8.6 5.2 7.3 6.7 0.4 3.0 2 1 0 3 3 3 0 FlxA-like protein bZIP_1 PF00170.21 GBG62861.1 - 2 8.6 12.5 2.4 8.3 1.3 3.8 2 1 1 3 3 3 0 bZIP transcription factor CENP-H PF05837.12 GBG62861.1 - 5.4 7.5 12.1 25 5.3 6.2 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Phage_GP20 PF06810.11 GBG62861.1 - 5.8 6.7 7.0 0.97 9.2 2.7 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF1690 PF07956.11 GBG62861.1 - 6.4 7.2 11.4 1.6 9.2 5.8 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF2353 PF09789.9 GBG62861.1 - 7.1 5.9 12.0 6.4 6.0 10.0 1.8 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DivIC PF04977.15 GBG62861.1 - 7.9 6.3 19.1 0.034 13.9 1.7 4.1 2 2 0 3 3 3 0 Septum formation initiator RVT_1 PF00078.27 GBG62862.1 - 1.1e-35 123.1 0.1 2e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62862.1 - 7.7e-06 25.9 0.0 5.5e-05 23.1 0.0 2.4 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase PCEMA1 PF07418.11 GBG62862.1 - 1.4 8.4 13.6 2.8 7.4 13.6 1.4 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 RT_RNaseH_2 PF17919.1 GBG62863.1 - 4.6e-27 94.0 0.0 9.7e-27 92.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62863.1 - 7.5e-24 84.0 0.0 1.4e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62863.1 - 5.6e-21 75.1 0.1 9.2e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62863.1 - 1.6e-15 56.9 0.9 3.1e-15 56.0 0.9 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG62863.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG62864.1 - 2.1e-20 73.0 0.0 4.2e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62864.1 - 2.6e-17 62.7 0.0 4.9e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62864.1 - 4.8e-15 55.8 0.0 1.1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG62864.1 - 1.6e-14 53.7 0.2 1.6e-14 53.7 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG62864.1 - 1.3e-09 38.0 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG62864.1 - 0.015 15.5 0.1 0.036 14.3 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG62865.1 - 0.0014 18.9 0.8 0.0028 17.9 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2097 PF09870.9 GBG62865.1 - 0.0087 16.2 0.4 5 7.4 0.0 3.1 2 1 1 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2097) Bromodomain PF00439.25 GBG62865.1 - 0.093 12.8 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Bromodomain RVT_1 PF00078.27 GBG62866.1 - 9.2e-08 31.9 0.0 3.1e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62866.1 - 0.0098 16.0 0.4 0.0098 16.0 0.4 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Adeno_hexon PF01065.19 GBG62866.1 - 2.2 7.0 4.3 3.6 6.3 4.3 1.2 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain RVT_1 PF00078.27 GBG62867.1 - 2e-92 308.7 4.1 3.7e-30 105.1 0.1 3.8 4 0 0 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62867.1 - 7.8e-44 147.8 2.8 2.9e-23 81.8 0.0 4.0 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62867.1 - 2.3e-29 101.8 1.4 3e-10 40.3 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62867.1 - 4.9e-18 65.0 1.8 1.5e-13 50.6 0.4 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG62867.1 - 1.7e-16 60.5 0.0 0.00099 19.6 0.0 5.3 5 0 0 5 5 5 3 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62867.1 - 6.6e-16 58.7 0.1 0.0016 19.1 0.0 5.2 5 0 0 5 5 5 3 Aspartyl protease RVP_2 PF08284.11 GBG62867.1 - 2.4e-08 33.8 0.0 0.00071 19.4 0.0 4.3 4 0 0 4 4 4 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62867.1 - 4.9e-06 26.3 0.0 0.11 12.3 0.0 3.8 3 0 0 3 3 3 2 Aspartyl protease rve PF00665.26 GBG62867.1 - 1e-05 25.7 0.0 2.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG62867.1 - 0.0003 21.0 1.7 0.0086 16.3 0.1 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein DUF1758 PF05585.12 GBG62867.1 - 0.15 11.8 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Putative peptidase (DUF1758) zf-CCHC_3 PF13917.6 GBG62867.1 - 0.4 10.7 1.5 15 5.6 0.2 2.7 2 0 0 2 2 2 0 Zinc knuckle Nop14 PF04147.12 GBG62868.1 - 2 6.5 4.6 2.6 6.2 4.6 1.2 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 GBG62868.1 - 5.9 6.8 15.5 8.8 6.3 15.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) AAA PF00004.29 GBG62871.1 - 2e-44 151.2 2.1 3.8e-44 150.3 0.0 2.4 3 1 1 4 4 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GBG62871.1 - 1.8e-09 37.4 0.1 9.6e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 GBG62871.1 - 6.7e-09 35.9 0.4 3.5e-08 33.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GBG62871.1 - 2.4e-07 31.1 0.5 7.5e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 GBG62871.1 - 3.1e-07 30.1 0.0 8.3e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GBG62871.1 - 3.7e-07 30.7 0.8 6.1e-05 23.5 0.0 2.8 2 2 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 GBG62871.1 - 3.3e-05 23.2 0.1 8.3e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GBG62871.1 - 3.9e-05 23.4 0.0 0.00015 21.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GBG62871.1 - 0.00016 22.2 0.1 0.00079 20.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GBG62871.1 - 0.00028 21.2 3.7 0.0084 16.4 0.1 2.8 2 1 1 3 3 2 1 AAA domain Sigma54_activat PF00158.26 GBG62871.1 - 0.00035 20.3 1.4 0.16 11.6 0.0 3.8 4 0 0 4 4 4 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 GBG62871.1 - 0.00045 20.0 0.3 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 GBG62871.1 - 0.00046 20.5 0.5 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GBG62871.1 - 0.0007 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 GBG62871.1 - 0.0013 18.9 0.2 0.008 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GBG62871.1 - 0.0016 17.8 0.1 0.0036 16.7 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GBG62871.1 - 0.0026 17.8 0.1 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 GBG62871.1 - 0.003 16.8 0.0 0.0064 15.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 GBG62871.1 - 0.0031 17.5 0.0 0.0079 16.2 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GBG62871.1 - 0.0084 15.6 0.1 0.061 12.8 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 GBG62871.1 - 0.0089 15.4 0.3 1.3 8.4 0.0 2.7 3 0 0 3 3 2 1 Bacterial TniB protein AAA_11 PF13086.6 GBG62871.1 - 0.01 15.7 1.4 0.31 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GBG62871.1 - 0.01 15.5 3.2 0.013 15.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GBG62871.1 - 0.011 15.6 0.0 0.075 12.9 0.0 2.4 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.6 GBG62871.1 - 0.014 15.1 0.1 0.014 15.1 0.1 1.9 2 1 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 GBG62871.1 - 0.016 14.3 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 GBG62871.1 - 0.02 14.7 0.0 0.067 13.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GBG62871.1 - 0.023 14.6 1.8 0.086 12.8 0.1 2.7 4 0 0 4 4 3 0 NACHT domain AAA_25 PF13481.6 GBG62871.1 - 0.027 14.1 0.2 0.027 14.1 0.2 2.7 2 1 1 3 3 3 0 AAA domain ATPase PF06745.13 GBG62871.1 - 0.035 13.4 3.3 0.44 9.9 0.0 3.0 3 0 0 3 3 3 0 KaiC DUF3450 PF11932.8 GBG62871.1 - 0.04 13.2 9.9 0.057 12.7 8.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ATPase_2 PF01637.18 GBG62871.1 - 0.067 13.1 0.8 1.8 8.4 0.0 2.8 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 GBG62871.1 - 0.088 12.0 2.0 0.5 9.5 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain Sigma54_activ_2 PF14532.6 GBG62871.1 - 0.089 12.9 0.2 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 GBG62871.1 - 0.15 12.6 0.5 1.1 9.8 0.0 2.6 2 1 0 2 2 2 0 ABC transporter APG6_N PF17675.1 GBG62871.1 - 0.19 12.3 9.6 0.35 11.4 9.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4972 PF16342.5 GBG62871.1 - 0.19 11.4 3.1 1.5 8.5 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) TMPIT PF07851.13 GBG62871.1 - 0.25 10.5 2.1 0.37 10.0 2.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein AAA_23 PF13476.6 GBG62871.1 - 0.31 11.5 7.5 18 5.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GBG62871.1 - 0.47 10.8 2.5 0.59 10.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain GvpG PF05120.12 GBG62871.1 - 2.7 8.1 9.0 2 8.5 6.9 1.9 2 0 0 2 2 1 0 Gas vesicle protein G HIP1_clath_bdg PF16515.5 GBG62871.1 - 5.7 7.6 12.8 7.8 7.2 10.4 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RVT_1 PF00078.27 GBG62872.1 - 2e-29 102.7 0.1 3.2e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG62872.1 - 1.2e-07 31.9 0.0 3.8e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG62872.1 - 0.042 14.5 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG62874.1 - 1.6e-33 114.7 0.0 3.7e-33 113.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62874.1 - 7.4e-30 103.3 0.1 1.6e-29 102.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62874.1 - 1.4e-28 100.0 0.1 2.4e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG62874.1 - 2.9e-16 59.3 0.1 6.6e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG62874.1 - 0.0027 18.3 0.0 0.0062 17.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62874.1 - 0.0049 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TolA_bind_tri PF16331.5 GBG62876.1 - 0.0074 16.3 4.1 0.0074 16.3 4.1 2.1 1 1 1 2 2 2 1 TolA binding protein trimerisation Spc29 PF17082.5 GBG62876.1 - 0.03 14.2 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF1664 PF07889.12 GBG62876.1 - 0.14 12.2 1.6 0.45 10.6 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 GBG62876.1 - 0.18 12.3 1.4 0.22 12.0 0.4 1.7 2 0 0 2 2 2 0 Fez1 DUF4187 PF13821.6 GBG62876.1 - 0.28 11.0 2.6 0.78 9.6 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Trimer_CC PF08954.11 GBG62876.1 - 0.54 9.9 4.6 9.2 5.9 2.8 3.0 1 1 1 2 2 2 0 Trimerisation motif ADIP PF11559.8 GBG62876.1 - 0.62 10.1 5.6 1.1 9.3 5.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 GBG62876.1 - 0.91 8.8 4.6 1.4 8.2 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.12 GBG62876.1 - 2.4 8.8 8.4 1.9 9.2 1.6 2.6 1 1 1 2 2 2 0 SlyX zf-CCHC PF00098.23 GBG62879.1 - 4.8e-06 26.4 1.1 1e-05 25.3 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG62879.1 - 0.026 14.5 1.6 0.08 12.9 1.6 1.8 1 0 0 1 1 1 0 Zinc knuckle VIT1 PF01988.19 GBG62879.1 - 1.4 8.7 3.3 3.4 7.5 3.3 1.6 1 0 0 1 1 1 0 VIT family zf-CCHC_4 PF14392.6 GBG62879.1 - 2.5 7.9 4.3 1.2 8.9 1.6 1.9 2 0 0 2 2 2 0 Zinc knuckle Ran_BP1 PF00638.18 GBG62880.1 - 1.1e-47 161.3 0.8 2e-47 160.5 0.8 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 GBG62880.1 - 4.1e-05 23.5 0.5 0.00011 22.1 0.5 1.7 1 1 0 1 1 1 1 WH1 domain Pep1_7 PF17232.2 GBG62880.1 - 0.73 10.3 6.6 0.31 11.5 0.7 2.4 2 0 0 2 2 2 0 Elicitor peptide 1-7 Dimer_Tnp_hAT PF05699.14 GBG62881.1 - 1.5e-06 27.9 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Cwf_Cwc_15 PF04889.12 GBG62881.1 - 0.023 14.4 5.1 0.047 13.4 5.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein gag-asp_proteas PF13975.6 GBG62882.1 - 0.00043 20.8 0.0 0.00089 19.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG62882.1 - 0.002 18.7 0.0 0.0037 17.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG62882.1 - 0.017 15.5 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease TRAP_alpha PF03896.16 GBG62882.1 - 0.33 10.1 1.8 0.44 9.7 1.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PTPRCAP PF15713.5 GBG62882.1 - 0.66 10.3 8.8 0.99 9.7 8.8 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG62882.1 - 2.9 6.1 6.9 3.1 6.0 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG62882.1 - 5.8 5.6 5.6 3.5 6.3 3.8 1.5 2 0 0 2 2 2 0 Presenilin CPSF100_C PF13299.6 GBG62882.1 - 7.9 6.6 8.3 14 5.8 8.3 1.4 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 GBG62882.1 - 9.6 5.9 8.7 12 5.6 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-A20 PF01754.16 GBG62883.1 - 3.5e-12 46.0 11.3 1.1e-11 44.5 11.3 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 GBG62883.1 - 5e-09 36.2 8.0 5e-09 36.2 8.0 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger zf-CCHC PF00098.23 GBG62885.1 - 6.9e-05 22.7 6.0 0.0002 21.3 6.0 1.9 1 0 0 1 1 1 1 Zinc knuckle DUF3046 PF11248.8 GBG62887.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) Dimer_Tnp_hAT PF05699.14 GBG62887.1 - 0.015 15.0 1.9 0.032 14.0 1.9 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG62887.1 - 3 8.0 22.5 0.045 13.6 3.9 3.8 3 0 0 3 3 3 0 AT hook motif zf-BED PF02892.15 GBG62888.1 - 0.027 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 BED zinc finger PyrI_C PF02748.15 GBG62888.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Nup54 PF13874.6 GBG62889.1 - 1.6e-05 25.0 8.2 0.027 14.6 3.1 2.1 2 0 0 2 2 2 2 Nucleoporin complex subunit 54 Laminin_II PF06009.12 GBG62889.1 - 0.0028 17.7 4.8 0.0048 16.9 4.1 1.7 1 1 1 2 2 2 1 Laminin Domain II Phage_GP20 PF06810.11 GBG62889.1 - 0.0081 16.0 5.6 0.0081 16.0 5.6 1.9 1 1 1 2 2 2 1 Phage minor structural protein GP20 PspA_IM30 PF04012.12 GBG62889.1 - 0.0086 15.7 6.3 0.017 14.7 6.3 1.6 1 1 0 1 1 1 1 PspA/IM30 family Bacillus_HBL PF05791.11 GBG62889.1 - 0.011 15.5 1.8 0.039 13.8 1.1 1.8 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.11 GBG62889.1 - 0.012 15.9 10.8 0.034 14.4 10.8 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ApoLp-III PF07464.11 GBG62889.1 - 0.023 14.8 3.6 0.037 14.1 3.6 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ADIP PF11559.8 GBG62889.1 - 0.024 14.7 10.8 0.026 14.6 8.3 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LUC7 PF03194.15 GBG62889.1 - 0.025 14.2 7.7 0.1 12.2 7.7 1.8 1 1 0 1 1 1 0 LUC7 N_terminus TMF_DNA_bd PF12329.8 GBG62889.1 - 0.029 14.4 9.7 0.029 14.4 9.7 3.3 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Cytochrom_B562 PF07361.11 GBG62889.1 - 0.029 15.0 4.6 3.3 8.4 1.2 2.3 1 1 1 2 2 2 0 Cytochrome b562 TPR_MLP1_2 PF07926.12 GBG62889.1 - 0.033 14.2 13.0 0.056 13.5 11.3 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 GBG62889.1 - 0.044 14.2 4.9 0.044 14.2 4.9 3.2 1 1 2 3 3 3 0 Cell division protein ZapB DUF1664 PF07889.12 GBG62889.1 - 0.073 13.1 5.3 0.45 10.6 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Herpes_UL6 PF01763.16 GBG62889.1 - 0.083 11.4 4.5 0.069 11.7 2.3 1.8 1 1 1 2 2 2 0 Herpesvirus UL6 like HK97-gp10_like PF04883.12 GBG62889.1 - 0.089 13.8 0.7 0.24 12.4 0.7 2.0 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component DUF848 PF05852.11 GBG62889.1 - 0.093 12.8 8.7 0.23 11.5 5.9 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3450 PF11932.8 GBG62889.1 - 0.1 11.9 5.7 0.43 9.8 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 GBG62889.1 - 0.17 12.2 6.7 0.44 10.9 2.9 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GBG62889.1 - 0.2 12.2 1.2 4.4 7.8 1.2 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HAUS-augmin3 PF14932.6 GBG62889.1 - 0.21 11.1 14.4 0.14 11.7 10.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 GBG62889.1 - 0.23 11.8 11.5 1.1 9.6 5.3 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin_2 PF14523.6 GBG62889.1 - 0.23 11.8 7.0 1 9.8 2.7 2.6 1 1 2 3 3 3 0 Syntaxin-like protein Spc7 PF08317.11 GBG62889.1 - 0.24 10.2 14.0 0.35 9.7 14.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 GBG62889.1 - 0.26 11.4 8.9 0.13 12.4 3.1 2.5 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 GBG62889.1 - 0.32 11.3 2.8 0.99 9.7 0.9 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 GBG62889.1 - 0.34 8.8 3.9 0.56 8.1 3.9 1.4 1 1 0 1 1 1 0 Prominin Mod_r PF07200.13 GBG62889.1 - 0.38 10.9 13.2 0.09 12.9 7.0 2.2 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CENP-H PF05837.12 GBG62889.1 - 0.42 11.0 13.2 3 8.3 7.7 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Atg14 PF10186.9 GBG62889.1 - 0.49 9.4 6.1 0.56 9.2 6.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med4 PF10018.9 GBG62889.1 - 0.51 10.0 9.3 1.9 8.2 8.4 2.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4446 PF14584.6 GBG62889.1 - 0.75 9.8 6.4 1.2 9.1 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) MIF4G_like_2 PF09090.11 GBG62889.1 - 0.91 8.9 7.9 7.2 6.0 7.9 2.0 1 1 0 1 1 1 0 MIF4G like DUF4407 PF14362.6 GBG62889.1 - 1.1 8.6 4.8 2.3 7.5 4.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMCO5 PF14992.6 GBG62889.1 - 1.2 8.6 14.4 0.87 9.1 12.8 1.6 1 1 0 1 1 1 0 TMCO5 family ALMT PF11744.8 GBG62889.1 - 1.9 7.2 6.0 2.2 7.0 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DivIVA PF05103.13 GBG62889.1 - 2.6 8.1 9.6 2.5 8.2 1.5 3.0 1 1 2 3 3 3 0 DivIVA protein YabA PF06156.13 GBG62889.1 - 3.2 8.4 12.3 1.3 9.7 6.1 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DASH_Dam1 PF08653.10 GBG62889.1 - 3.2 7.6 4.8 11 5.9 0.1 3.5 4 1 0 4 4 4 0 DASH complex subunit Dam1 CLZ PF16526.5 GBG62889.1 - 4.1 7.8 15.1 5.7 7.4 7.6 3.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YtxH PF12732.7 GBG62889.1 - 4.6 7.8 6.7 72 4.0 5.1 2.6 1 1 1 2 2 2 0 YtxH-like protein Seryl_tRNA_N PF02403.22 GBG62889.1 - 5.4 7.3 14.9 2.9 8.2 7.8 2.3 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DHR10 PF18595.1 GBG62889.1 - 5.8 7.0 18.8 9 6.4 16.3 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Cep57_MT_bd PF06657.13 GBG62889.1 - 7 7.2 11.9 1.2 9.7 4.5 2.7 2 2 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 UPF0242 PF06785.11 GBG62889.1 - 7.9 6.5 15.9 1e+02 2.9 15.9 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 GBG62889.1 - 9 6.8 9.5 8.4 6.9 4.3 3.4 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 GBG62889.1 - 9.4 6.4 18.6 0.19 11.9 6.0 3.4 2 2 1 3 3 3 0 bZIP transcription factor Histone PF00125.24 GBG62890.1 - 4.3e-21 75.7 0.8 4.3e-21 75.7 0.8 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG62890.1 - 0.07 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 CENP-S protein TFIID-31kDa PF02291.15 GBG62890.1 - 0.15 12.1 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RVT_1 PF00078.27 GBG62891.1 - 3e-10 40.0 0.1 3.8e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_ligase_A_M PF01068.21 GBG62891.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase domain Kinesin PF00225.23 GBG62893.1 - 8.9e-57 192.5 0.0 1.1e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain NUDIX PF00293.28 GBG62893.1 - 0.064 13.3 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain DUF3138 PF11336.8 GBG62895.1 - 0.74 8.4 2.6 1.2 7.6 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) REV PF00424.18 GBG62895.1 - 3.5 7.7 5.8 1.2 9.2 1.3 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) BAF1_ABF1 PF04684.13 GBG62895.1 - 5.1 6.0 14.7 7.2 5.5 14.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3629 PF12302.8 GBG62895.1 - 8.2 5.8 9.8 19 4.6 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) RVT_1 PF00078.27 GBG62896.1 - 1.5e-13 50.8 1.2 1.6e-11 44.2 0.3 2.9 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG62896.1 - 1.4e-08 34.6 0.0 3.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62896.1 - 8.6e-06 26.3 0.0 2.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62896.1 - 8.7e-06 25.5 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62896.1 - 1.9e-05 25.1 0.0 6.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG62896.1 - 0.033 14.0 0.2 0.067 13.0 0.2 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF2730 PF10805.8 GBG62896.1 - 0.045 13.9 0.2 0.35 11.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Nuc_N PF14448.6 GBG62896.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Nuclease N terminal Fur_reg_FbpA PF13076.6 GBG62896.1 - 0.13 12.0 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 Fur-regulated basic protein A CorA PF01544.18 GBG62896.1 - 0.91 8.8 2.9 0.54 9.5 0.1 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF3719 PF12516.8 GBG62897.1 - 0.17 11.6 0.2 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) Dynein_light PF01221.18 GBG62897.1 - 1 9.7 2.4 2.4 8.5 2.4 1.6 1 0 0 1 1 1 0 Dynein light chain type 1 RVT_1 PF00078.27 GBG62898.1 - 5.2e-29 101.3 0.0 1.3e-28 100.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62898.1 - 1.2e-19 70.1 0.0 3.4e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62898.1 - 1.3e-19 70.0 0.4 2.6e-19 69.1 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG62898.1 - 2.9e-17 62.9 0.0 1.1e-16 61.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62898.1 - 4.2e-07 30.2 0.1 1.4e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG62898.1 - 0.00098 19.3 0.1 0.0024 18.0 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 GBG62898.1 - 0.0018 18.0 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG62898.1 - 0.082 13.2 0.1 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG62898.1 - 0.33 11.0 2.7 0.92 9.6 2.7 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation Topoisom_I_N PF02919.15 GBG62899.1 - 0.31 10.5 10.0 0.029 13.9 4.4 1.9 1 1 1 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RT_RNaseH PF17917.1 GBG62900.1 - 1.1e-22 80.3 2.4 3.2e-22 78.8 0.0 2.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62900.1 - 5.4e-22 77.7 1.2 2e-21 75.9 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG62900.1 - 0.0017 18.1 0.6 0.0052 16.5 0.6 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Integrase_H2C2 PF17921.1 GBG62900.1 - 0.003 17.6 0.3 0.024 14.7 0.0 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain TMV_coat PF00721.21 GBG62900.1 - 0.023 14.6 0.2 4.3 7.2 0.0 2.7 2 1 0 2 2 2 0 Virus coat protein (TMV like) Nif11 PF07862.11 GBG62900.1 - 0.083 13.2 1.2 8 6.9 0.0 3.5 2 1 1 3 3 3 0 Nif11 domain MCH PF02289.16 GBG62900.1 - 0.34 10.2 1.0 0.58 9.4 1.0 1.3 1 0 0 1 1 1 0 Cyclohydrolase (MCH) MAD PF05557.13 GBG62900.1 - 0.53 8.6 37.5 0.69 8.2 37.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF2383 PF09537.10 GBG62900.1 - 1.5 9.2 17.2 1.7 9.0 6.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) Golgin_A5 PF09787.9 GBG62900.1 - 3.1 7.2 36.4 5 6.5 36.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 RVP_2 PF08284.11 GBG62901.1 - 2e-07 30.8 0.0 4.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG62901.1 - 6.6e-07 29.9 0.0 2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62901.1 - 6.6e-06 26.6 0.0 3.6e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG62901.1 - 0.0027 17.5 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG62901.1 - 0.048 13.9 6.3 0.069 13.4 0.0 3.2 3 0 0 3 3 3 0 Retrotransposon gag protein Peptidase_C14 PF00656.22 GBG62901.1 - 0.075 13.0 0.6 0.19 11.7 0.6 1.7 1 0 0 1 1 1 0 Caspase domain RT_RNaseH_2 PF17919.1 GBG62902.1 - 6.9e-31 106.2 0.0 1.9e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62902.1 - 1.9e-29 102.0 0.0 3.6e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62902.1 - 2.6e-28 99.1 0.0 4.2e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AhpC-TSA PF00578.21 GBG62903.1 - 5.5e-42 142.6 0.0 7.4e-42 142.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GBG62903.1 - 6.9e-15 55.0 0.0 9.7e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GBG62903.1 - 7.1e-11 41.8 0.3 1.4e-10 40.9 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF5426 PF17473.2 GBG62903.1 - 0.1 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5426) S1 PF00575.23 GBG62904.1 - 2.7e-44 149.4 4.8 1.2e-20 73.6 0.6 3.2 3 0 0 3 3 3 3 S1 RNA binding domain DUF2110 PF09883.9 GBG62904.1 - 0.0012 18.5 0.2 0.18 11.3 0.0 2.8 2 1 1 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2110) SGS PF05002.15 GBG62904.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 SGS domain WD40 PF00400.32 GBG62907.1 - 1.1e-10 41.8 2.8 6.4e-08 33.1 0.2 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG62907.1 - 8.1e-07 29.3 0.0 0.068 13.5 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 GBG62907.1 - 0.064 12.3 0.0 0.077 12.0 0.0 1.0 1 0 0 1 1 1 0 Coatomer WD associated region Prenyltransf PF01255.19 GBG62909.1 - 2.3e-71 239.9 0.1 1.2e-46 159.1 0.1 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase RNA_pol_3_Rpc31 PF11705.8 GBG62909.1 - 0.0039 17.5 25.8 0.058 13.6 15.1 2.3 2 0 0 2 2 2 2 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.12 GBG62909.1 - 0.0049 16.3 23.8 0.017 14.5 13.7 2.3 2 0 0 2 2 2 2 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 GBG62909.1 - 0.0068 15.2 7.0 0.011 14.6 7.0 1.2 1 0 0 1 1 1 1 Presenilin Mpp10 PF04006.12 GBG62909.1 - 0.007 14.9 24.6 0.026 13.0 14.6 2.1 2 0 0 2 2 2 2 Mpp10 protein BSP_II PF05432.11 GBG62909.1 - 0.015 15.0 5.8 0.015 15.0 5.8 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) RXT2_N PF08595.11 GBG62909.1 - 0.017 15.2 14.1 0.24 11.4 5.7 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal CPSF100_C PF13299.6 GBG62909.1 - 0.097 12.9 9.8 0.51 10.5 3.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MRNIP PF15749.5 GBG62909.1 - 0.11 13.2 12.8 1.3 9.8 1.1 2.3 2 0 0 2 2 2 0 MRN-interacting protein DUF4820 PF16091.5 GBG62909.1 - 0.11 11.8 12.9 0.5 9.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RPN2_C PF18004.1 GBG62909.1 - 0.12 12.3 17.0 0.82 9.6 9.2 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain TFIIA PF03153.13 GBG62909.1 - 0.48 10.4 11.8 0.68 9.9 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIF_C PF14721.6 GBG62909.1 - 0.49 10.7 6.7 0.82 10.0 1.5 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Folliculin PF11704.8 GBG62909.1 - 0.57 10.0 5.4 8.1 6.3 0.1 3.0 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3391 PF11871.8 GBG62909.1 - 0.67 10.5 10.7 1.2 9.6 4.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) SAPS PF04499.15 GBG62909.1 - 0.73 8.6 6.0 0.99 8.1 6.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EIIBC-GUT_N PF03612.14 GBG62909.1 - 1 9.1 9.3 5.9 6.6 2.3 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus SpoIIP PF07454.11 GBG62909.1 - 1.2 8.5 11.8 1.1 8.7 4.7 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 GBG62909.1 - 1.2 8.9 18.4 4.7 6.9 0.6 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NOA36 PF06524.12 GBG62909.1 - 1.3 8.3 25.8 0.69 9.2 14.7 2.2 2 0 0 2 2 2 0 NOA36 protein Tim54 PF11711.8 GBG62909.1 - 1.4 7.6 12.9 2.5 6.8 6.6 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SAP18 PF06487.12 GBG62909.1 - 2.5 8.3 4.9 0.84 9.8 0.0 2.2 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) RNA_pol_Rpc4 PF05132.14 GBG62909.1 - 2.7 8.4 9.9 2.2 8.7 3.7 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 TFB6 PF17110.5 GBG62909.1 - 2.7 7.7 15.7 3.8 7.2 7.0 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF719 PF05334.13 GBG62909.1 - 3.5 7.8 13.6 7 6.8 6.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Prothymosin PF03247.14 GBG62909.1 - 3.7 8.0 55.7 3.9 8.0 35.8 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF4637 PF15470.6 GBG62909.1 - 4.6 7.0 33.5 2.3 7.9 19.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Sigma70_ner PF04546.13 GBG62909.1 - 4.6 7.1 27.5 5.9 6.7 14.9 2.5 2 1 0 2 2 2 0 Sigma-70, non-essential region Vfa1 PF08432.10 GBG62909.1 - 4.8 7.5 15.5 5.8 7.2 0.3 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CDC27 PF09507.10 GBG62909.1 - 5.5 6.3 16.9 9.1 5.5 0.7 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 RPA43_OB PF17875.1 GBG62909.1 - 5.9 7.5 14.2 14 6.3 0.6 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF4628 PF15429.6 GBG62909.1 - 7.5 6.1 9.5 4.7 6.8 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) G0-G1_switch_2 PF15103.6 GBG62909.1 - 8.1 6.9 11.2 19 5.7 0.5 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF3408 PF11888.8 GBG62909.1 - 8.9 6.5 19.4 14 5.8 10.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF3306 PF11748.8 GBG62909.1 - 9.4 7.1 13.2 7 7.5 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) XAP5 PF04921.14 GBG62909.1 - 9.9 5.9 15.4 3.7 7.3 7.4 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator OB_NTP_bind PF07717.16 GBG62910.1 - 4e-21 75.2 0.0 8.2e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GBG62910.1 - 7.9e-19 67.9 0.0 1.6e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) 23ISL PF16620.5 GBG62910.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Unstructured linker between I-set domains 2 and 3 on MYLCK Helicase_C PF00271.31 GBG62911.1 - 3.4e-11 43.5 0.0 8.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GBG62911.1 - 1.4e-09 38.0 0.0 2.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DND1_DSRM PF14709.7 GBG62911.1 - 0.00043 20.5 1.3 0.0015 18.7 0.1 2.6 2 1 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_19 PF13245.6 GBG62911.1 - 0.00051 20.4 0.0 0.0016 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GBG62911.1 - 0.0008 18.5 0.1 0.0029 16.7 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase PF06745.13 GBG62911.1 - 0.022 14.1 0.6 0.099 12.0 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF503 PF04456.12 GBG62911.1 - 0.07 13.0 0.1 0.19 11.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF503) AAA_22 PF13401.6 GBG62911.1 - 0.12 12.6 0.3 0.66 10.2 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GBG62911.1 - 0.14 12.6 0.1 0.93 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 GBG62911.1 - 0.33 11.4 0.0 0.33 11.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain SH3_13 PF18335.1 GBG62912.1 - 5.5e-21 74.2 0.3 1.2e-20 73.1 0.3 1.6 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_30 PF13604.6 GBG62912.1 - 4.2e-17 62.5 0.0 9.7e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG62912.1 - 8.7e-17 61.8 0.0 1.7e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain HHH_4 PF14490.6 GBG62912.1 - 9e-16 57.6 0.0 1.2e-13 50.8 0.0 2.7 1 1 1 2 2 2 1 Helix-hairpin-helix containing domain UvrD_C_2 PF13538.6 GBG62912.1 - 3.3e-15 55.6 0.0 7e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HHH_5 PF14520.6 GBG62912.1 - 6.2e-08 33.1 0.8 2.5e-07 31.2 0.1 2.4 3 0 0 3 3 3 1 Helix-hairpin-helix domain Viral_helicase1 PF01443.18 GBG62912.1 - 2e-06 27.7 0.0 0.0004 20.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase HHH PF00633.23 GBG62912.1 - 0.00025 20.8 0.3 0.017 15.0 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif AAA_11 PF13086.6 GBG62912.1 - 0.0045 16.8 0.0 0.0098 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG62912.1 - 0.029 14.8 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C PF13361.6 GBG62912.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 GBG62912.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Helicase PIF1 PF05970.14 GBG62912.1 - 0.088 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Mg_chelatase PF01078.21 GBG62912.1 - 0.12 11.8 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HHH_2 PF12826.7 GBG62912.1 - 0.14 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif RT_RNaseH_2 PF17919.1 GBG62915.1 - 9.8e-26 89.7 0.0 2.5e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62915.1 - 2.7e-25 88.7 0.1 8.1e-25 87.1 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62915.1 - 0.035 13.6 0.1 0.077 12.5 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ATC_hydrolase PF14196.6 GBG62915.1 - 0.35 11.6 3.7 2.6 8.8 0.0 2.7 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Phage_GPO PF05929.11 GBG62915.1 - 0.51 9.9 0.0 0.51 9.9 0.0 2.9 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Pkinase_Tyr PF07714.17 GBG62916.1 - 8.1e-38 130.2 0.1 2.3e-37 128.7 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG62916.1 - 4.8e-31 108.1 0.0 2e-30 106.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG62916.1 - 0.015 14.1 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GBG62916.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4106 PF13388.6 GBG62918.1 - 0.036 13.3 1.0 0.052 12.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RT_RNaseH_2 PF17919.1 GBG62919.1 - 2.2e-23 82.2 0.0 3.1e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62919.1 - 6.8e-21 74.5 0.0 1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62920.1 - 7.8e-30 104.0 0.0 1.3e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62920.1 - 3.1e-18 66.0 0.0 6.4e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62920.1 - 6.1e-16 58.3 0.0 1.3e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62920.1 - 2.6e-13 50.2 0.1 6.9e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG62920.1 - 9.6e-09 35.2 0.0 2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG62920.1 - 2.4e-05 24.4 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG62921.1 - 7.8e-21 74.0 0.0 1.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62921.1 - 4.7e-16 59.0 0.0 9e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62921.1 - 3e-11 43.3 0.1 4.6e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG62921.1 - 0.53 8.4 10.2 0.68 8.1 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG62921.1 - 0.97 8.8 10.1 1.4 8.3 10.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG62921.1 - 4.3 5.5 9.6 6 5.0 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP70 PF00012.20 GBG62922.1 - 1.6e-266 885.3 12.6 1.8e-266 885.1 12.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG62922.1 - 6.5e-19 67.9 0.3 1.6e-17 63.4 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GBG62922.1 - 0.00026 21.3 4.8 0.38 11.2 0.3 3.8 3 2 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 GBG62922.1 - 0.015 14.3 0.3 0.28 10.1 0.2 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 GBG62922.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 GBG62922.1 - 0.2 10.9 6.8 0.19 11.0 0.2 3.1 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase RVT_1 PF00078.27 GBG62923.1 - 2.9e-26 92.4 0.1 2.9e-26 92.4 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG62923.1 - 0.013 16.1 0.0 0.089 13.5 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease PPR PF01535.20 GBG62924.1 - 7.4e-12 44.7 8.4 0.0086 16.3 0.9 5.0 4 0 0 4 4 4 4 PPR repeat PPR_2 PF13041.6 GBG62924.1 - 7.6e-11 42.0 1.4 0.044 14.0 0.2 5.4 5 1 1 6 6 6 3 PPR repeat family PPR_1 PF12854.7 GBG62924.1 - 1.9e-07 30.7 0.3 0.00033 20.3 0.0 3.8 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.6 GBG62924.1 - 0.005 17.6 0.0 6.8 7.8 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG62924.1 - 0.008 16.7 0.0 0.14 12.7 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat FAM199X PF15814.5 GBG62924.1 - 0.13 11.3 14.0 0.24 10.4 14.0 1.4 1 0 0 1 1 1 0 Protein family FAM199X Apt1 PF10351.9 GBG62924.1 - 0.18 10.7 4.9 0.27 10.1 4.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Asp_protease_2 PF13650.6 GBG62925.1 - 3.5e-05 24.4 0.0 6.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG62925.1 - 0.00011 22.6 0.0 0.00025 21.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG62925.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG62925.1 - 0.0097 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease OsmC PF02566.19 GBG62925.1 - 0.37 11.3 3.8 0.42 11.1 2.0 1.9 2 0 0 2 2 2 0 OsmC-like protein AMP-binding PF00501.28 GBG62926.1 - 4.5e-104 348.4 0.0 9.4e-104 347.3 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 GBG62926.1 - 0.00013 22.9 0.1 0.00039 21.3 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_11 PF08241.12 GBG62927.1 - 4.9e-15 56.0 0.0 1.5e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG62927.1 - 1.3e-13 51.4 0.0 3.8e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG62927.1 - 4.6e-09 36.9 0.0 9.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG62927.1 - 6.5e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GBG62927.1 - 9.2e-06 25.6 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG62927.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 GBG62927.1 - 0.0014 17.3 0.0 0.0021 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 GBG62927.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF3422 PF11902.8 GBG62930.1 - 0.12 11.4 1.7 3 6.9 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3422) CENP-H PF05837.12 GBG62930.1 - 0.45 10.9 9.0 0.14 12.5 5.7 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Folliculin PF11704.8 GBG62930.1 - 5.6 6.8 7.9 3.9 7.3 3.0 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DDE_Tnp_4 PF13359.6 GBG62931.1 - 8.6e-11 41.7 0.0 3.1e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG62931.1 - 0.0031 17.2 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG62932.1 - 3.5e-07 30.5 1.3 1.5e-06 28.5 0.4 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain CDC73_N PF16050.5 GBG62932.1 - 0.63 9.3 2.6 1.1 8.5 2.6 1.2 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal PLAC8 PF04749.17 GBG62933.1 - 1.1e-14 55.2 24.0 1.5e-13 51.5 24.0 2.1 1 1 0 1 1 1 1 PLAC8 family DMSP_lyase PF16867.5 GBG62933.1 - 0.09 12.4 0.8 0.15 11.7 0.8 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase ERCC3_RAD25_C PF16203.5 GBG62934.1 - 1.3e-116 388.1 0.2 1.8e-116 387.7 0.2 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 GBG62934.1 - 4.2e-12 46.3 0.0 7.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 GBG62934.1 - 6.5e-12 45.8 0.2 1.8e-11 44.4 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG62934.1 - 2.5e-05 24.3 0.0 7.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RT_RNaseH PF17917.1 GBG62935.1 - 5.8e-19 68.3 0.5 1.4e-18 67.1 0.5 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62935.1 - 1.4e-12 47.5 0.1 3.6e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mannitol_dh_C PF08125.13 GBG62935.1 - 0.064 12.7 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain Voltage_CLC PF00654.20 GBG62936.1 - 3.8e-96 322.4 11.1 3.8e-96 322.4 11.1 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 GBG62936.1 - 1.2e-07 32.0 0.0 5.6e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 CBS domain DUF4834 PF16118.5 GBG62936.1 - 0.29 12.1 1.9 1 10.3 1.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 GBG62936.1 - 1.3 7.8 7.7 1.9 7.3 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 GBG62936.1 - 1.5 8.4 8.8 2.5 7.6 8.8 1.3 1 0 0 1 1 1 0 Spt20 family PEHE PF15275.6 GBG62936.1 - 2 9.0 8.1 3.6 8.2 8.1 1.3 1 0 0 1 1 1 0 PEHE domain SLD5_C PF16922.5 GBG62937.1 - 3e-13 49.7 0.0 6.9e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 GBG62937.1 - 3.3e-07 30.7 1.7 5.6e-07 30.0 1.7 1.4 1 0 0 1 1 1 1 GINS complex protein SMP PF04927.12 GBG62938.1 - 2.8e-20 72.5 13.4 1.6e-10 41.3 2.3 2.5 2 0 0 2 2 2 2 Seed maturation protein DLEU7 PF15760.5 GBG62938.1 - 7 6.1 11.6 0.56 9.7 6.0 1.8 2 0 0 2 2 2 0 Leukemia-associated protein 7 RT_RNaseH PF17917.1 GBG62939.1 - 1.1e-19 70.7 0.0 1.4e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62939.1 - 4.3e-12 45.9 0.0 6.9e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SMP PF04927.12 GBG62940.1 - 5.3e-17 62.0 9.3 2.9e-09 37.3 2.3 2.4 2 0 0 2 2 2 2 Seed maturation protein Pribosyltran PF00156.27 GBG62941.1 - 1.3e-21 76.8 0.1 1.8e-21 76.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GBG62941.1 - 0.0071 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF659 PF04937.15 GBG62942.1 - 2.7e-13 50.1 0.0 4.7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG62942.1 - 0.00041 20.1 0.3 0.00081 19.1 0.3 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region IF-2B PF01008.17 GBG62944.1 - 9.1e-65 218.7 0.0 1.1e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family RsbU_N PF08673.10 GBG62947.1 - 0.043 13.9 0.1 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF2389 PF09493.10 GBG62947.1 - 0.22 12.2 0.4 13 6.6 0.0 2.4 2 0 0 2 2 2 0 Tryptophan-rich protein (DUF2389) Dimer_Tnp_hAT PF05699.14 GBG62948.1 - 4.2e-05 23.3 0.3 8.9e-05 22.2 0.3 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG62949.1 - 7.8e-33 112.5 0.0 1.4e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62949.1 - 1.3e-31 109.8 0.1 2.1e-31 109.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62949.1 - 5.2e-29 100.6 0.1 8.9e-29 99.9 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Oxysterol_BP PF01237.18 GBG62950.1 - 4.1e-125 417.5 0.0 5.4e-125 417.1 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Gpr1_Fun34_YaaH PF01184.19 GBG62951.1 - 2.1e-41 141.8 20.0 2.7e-41 141.5 20.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 GBG62951.1 - 0.0065 16.9 12.3 0.29 11.6 0.3 3.4 1 1 2 3 3 3 2 Domain of unknown function (DUF202) Tetraspanin PF00335.20 GBG62951.1 - 0.44 10.2 8.2 0.47 10.1 7.3 1.5 1 1 0 1 1 1 0 Tetraspanin family RT_RNaseH PF17917.1 GBG62952.1 - 2.1e-18 66.5 0.1 4.8e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62952.1 - 9.2e-16 57.7 0.1 2.4e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62952.1 - 5.3e-15 55.7 0.0 1.8e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG62952.1 - 2.6e-10 40.2 0.1 6.2e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG62952.1 - 0.011 15.6 1.7 0.032 14.2 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle LegC3_N PF18654.1 GBG62952.1 - 0.12 11.6 4.7 0.22 10.8 4.7 1.3 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain Rotamase PF00639.21 GBG62952.1 - 0.2 12.6 1.4 0.68 10.9 1.4 2.0 1 0 0 1 1 1 0 PPIC-type PPIASE domain Rrn6 PF10214.9 GBG62952.1 - 2.1 6.7 7.2 3.2 6.1 7.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM199X PF15814.5 GBG62952.1 - 6.1 5.8 6.4 11 5.0 6.4 1.3 1 0 0 1 1 1 0 Protein family FAM199X ExsD PF16806.5 GBG62953.1 - 0.085 12.8 0.0 8.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Antiactivator protein ExsD HemY_N PF07219.13 GBG62953.1 - 0.49 10.6 2.0 1.1 9.5 0.5 2.0 2 0 0 2 2 2 0 HemY protein N-terminus DHHC PF01529.20 GBG62954.1 - 5e-39 133.5 14.1 5e-39 133.5 14.1 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase PAP_PilO PF06864.12 GBG62954.1 - 0.012 14.5 3.9 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Pilin accessory protein (PilO) DUF3682 PF12446.8 GBG62954.1 - 0.014 15.9 9.4 0.034 14.6 9.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) TFIIA PF03153.13 GBG62954.1 - 0.048 13.6 9.6 0.066 13.2 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OppC_N PF12911.7 GBG62954.1 - 0.26 11.3 1.2 14 5.7 0.1 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C 7tm_7 PF08395.12 GBG62954.1 - 3.4 6.8 12.6 0.025 13.8 2.4 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor Spt20 PF12090.8 GBG62954.1 - 7.5 6.1 18.0 7.4 6.1 15.9 1.8 2 0 0 2 2 2 0 Spt20 family Integrase_H2C2 PF17921.1 GBG62955.1 - 3.1e-13 49.6 0.1 9.8e-13 48.0 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62955.1 - 2.2e-12 47.2 0.0 5.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG62955.1 - 0.0093 15.7 0.0 0.035 13.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_2 PF13696.6 GBG62955.1 - 0.013 15.3 1.0 0.03 14.1 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG62955.1 - 0.33 11.1 1.5 1 9.5 1.5 1.9 1 0 0 1 1 1 0 Zinc knuckle ACC_epsilon PF13822.6 GBG62956.1 - 2.6 8.8 6.9 0.53 11.0 1.6 2.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit ANXA2R PF15721.5 GBG62956.1 - 3.1 8.3 7.0 2.1 8.9 4.5 1.9 1 1 1 2 2 2 0 Annexin-2 receptor Uds1 PF15456.6 GBG62957.1 - 0.065 13.4 0.9 0.17 12.1 0.9 1.6 1 0 0 1 1 1 0 Up-regulated During Septation FlaC_arch PF05377.11 GBG62958.1 - 0.047 14.1 0.3 2.2 8.7 0.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 GBG62958.1 - 0.1 13.2 0.6 0.1 13.2 0.6 4.6 3 2 1 4 4 4 0 SlyX NPV_P10 PF05531.12 GBG62958.1 - 0.16 12.4 5.4 2.6 8.5 5.4 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FANCM-MHF_bd PF16783.5 GBG62958.1 - 0.4 10.8 6.6 0.066 13.3 1.9 2.2 2 0 0 2 2 2 0 FANCM to MHF binding domain DUF2500 PF10694.9 GBG62958.1 - 0.5 10.9 3.0 1 9.9 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Presenilin PF01080.17 GBG62958.1 - 8.3 5.1 10.6 12 4.6 10.6 1.4 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG62959.1 - 9.8e-28 97.2 0.0 1.7e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62959.1 - 7.6e-27 93.3 0.1 1.6e-26 92.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62959.1 - 7.2e-22 77.7 0.3 1.3e-21 76.9 0.3 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG62959.1 - 5.1e-06 26.7 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG62959.1 - 0.13 11.9 2.8 0.16 11.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) RT_RNaseH_2 PF17919.1 GBG62960.1 - 1.8e-33 114.6 0.0 3.5e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62960.1 - 1.8e-29 102.1 0.1 3.4e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG62960.1 - 2e-21 75.9 24.6 0.00014 22.5 0.5 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG62960.1 - 3.9e-08 33.5 0.5 8.8e-05 22.7 0.0 3.9 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zf-CCHC PF00098.23 GBG62961.1 - 0.017 15.2 1.8 0.036 14.2 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG62962.1 - 1.4e-26 92.4 0.0 3.7e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG62962.1 - 1.4e-25 90.1 0.1 2.8e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG62962.1 - 3.7e-24 85.0 0.0 8.9e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG62962.1 - 0.00054 20.2 6.1 0.02 15.1 0.0 4.0 4 0 0 4 4 4 2 Retrotransposon gag protein zf-CCHC_4 PF14392.6 GBG62962.1 - 0.19 11.5 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG62962.1 - 0.23 11.6 0.5 0.54 10.4 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle HALZ PF02183.18 GBG62963.1 - 0.11 12.8 0.7 4.9 7.5 0.3 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 GBG62963.1 - 0.11 12.9 1.9 0.43 11.0 0.2 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) LPP PF04728.13 GBG62963.1 - 0.4 11.1 2.9 12 6.4 1.3 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper UbiA PF01040.18 GBG62965.1 - 2.2e-34 118.9 27.9 3.1e-34 118.4 27.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family RT_RNaseH_2 PF17919.1 GBG62966.1 - 3.2e-28 97.7 0.0 1.1e-27 95.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62966.1 - 1.7e-26 92.5 0.0 4.5e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62966.1 - 1.2e-05 25.4 4.2 0.00028 21.0 4.2 2.6 1 1 0 1 1 1 1 Integrase zinc binding domain Ras PF00071.22 GBG62967.1 - 5.3e-66 221.2 0.5 6.1e-66 221.0 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG62967.1 - 5.1e-35 120.3 0.1 8.5e-35 119.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG62967.1 - 2.3e-15 56.5 0.2 2.9e-15 56.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GBG62967.1 - 1.4e-05 24.6 0.1 1.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GBG62967.1 - 2.5e-05 23.9 0.3 6.9e-05 22.5 0.2 1.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GBG62967.1 - 2.7e-05 24.2 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG62967.1 - 7.9e-05 22.6 0.2 0.25 11.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 GBG62967.1 - 0.016 15.0 0.4 0.17 11.6 0.4 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GBG62967.1 - 0.016 14.7 0.1 0.025 14.0 0.1 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GBG62967.1 - 0.027 14.0 0.0 0.36 10.3 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 GBG62967.1 - 0.046 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG62967.1 - 0.048 14.0 0.0 0.072 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 GBG62967.1 - 0.088 11.9 0.0 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain AAA PF00004.29 GBG62967.1 - 0.1 13.0 0.0 3.4 8.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG62967.1 - 0.14 12.5 0.1 0.46 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GBG62967.1 - 0.15 12.0 0.1 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Coatomer_E PF04733.14 GBG62968.1 - 6.3e-90 301.5 1.6 2.4e-72 243.8 0.2 2.0 1 1 1 2 2 2 2 Coatomer epsilon subunit TPR_19 PF14559.6 GBG62968.1 - 1.2e-05 25.7 0.9 0.061 13.8 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GBG62968.1 - 0.0011 19.2 0.0 0.23 11.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG62968.1 - 0.0025 17.8 4.3 1.8 8.9 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG62968.1 - 0.0097 16.7 0.1 1.3 10.0 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG62968.1 - 0.065 13.6 0.0 1.3 9.6 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG62968.1 - 0.15 11.9 5.3 35 4.4 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Histone PF00125.24 GBG62969.1 - 6.2e-24 84.8 1.3 1.4e-23 83.7 1.3 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF659 PF04937.15 GBG62969.1 - 7.7e-08 32.3 0.0 1.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CENP-S PF15630.6 GBG62969.1 - 0.036 14.5 0.5 0.092 13.1 0.1 1.9 2 0 0 2 2 2 0 CENP-S protein DUF1296 PF06972.11 GBG62970.1 - 2.3e-27 94.9 0.6 3.7e-27 94.2 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) Robl_LC7 PF03259.17 GBG62971.1 - 7.6e-24 83.3 0.0 8e-16 57.6 0.0 2.0 1 1 1 2 2 2 2 Roadblock/LC7 domain LAMTOR5 PF16672.5 GBG62971.1 - 0.0025 17.7 0.0 0.0036 17.2 0.0 1.5 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 Fucose_iso_C PF02952.17 GBG62971.1 - 0.087 12.5 0.1 0.67 9.7 0.0 1.9 1 1 1 2 2 2 0 L-fucose isomerase, C-terminal domain DUF659 PF04937.15 GBG62972.1 - 1.2e-13 51.2 0.0 3.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Presenilin PF01080.17 GBG62972.1 - 1 8.0 25.4 1.9 7.1 25.4 1.5 1 0 0 1 1 1 0 Presenilin DUF3537 PF12056.8 GBG62972.1 - 2.8 6.7 0.0 2.8 6.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3537) Myc_N PF01056.18 GBG62973.1 - 0.079 12.8 7.0 0.1 12.5 7.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Pox_Ag35 PF03286.14 GBG62973.1 - 0.35 10.6 7.5 0.46 10.2 7.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 GBG62973.1 - 7.5 5.8 13.9 8.8 5.5 13.9 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 GBG62973.1 - 8 6.6 19.8 9.7 6.4 19.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nup96 PF12110.8 GBG62974.1 - 5.5e-64 216.1 0.1 1.1e-63 215.1 0.1 1.5 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 GBG62974.1 - 1.9e-39 135.2 0.0 3.1e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Fer4 PF00037.27 GBG62976.1 - 6.6e-15 54.2 16.3 2e-08 33.7 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 GBG62976.1 - 1.8e-13 50.9 10.9 3.4e-13 49.9 10.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 GBG62976.1 - 4e-11 43.7 5.5 5.6e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 GBG62976.1 - 2.4e-10 40.4 4.0 6.2e-05 23.0 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 GBG62976.1 - 2.5e-09 37.4 1.4 0.0005 20.5 0.1 2.6 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GBG62976.1 - 5.1e-09 36.1 21.4 6.7e-07 29.3 12.4 2.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 GBG62976.1 - 7.6e-09 35.6 10.6 1.3e-08 34.9 10.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 GBG62976.1 - 2e-07 30.8 17.7 0.00024 21.0 5.3 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 GBG62976.1 - 3.2e-07 30.1 12.9 0.0028 17.6 3.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 GBG62976.1 - 2.3e-05 24.5 11.6 0.00092 19.5 2.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 GBG62976.1 - 0.00035 21.0 12.6 0.037 14.6 13.4 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 GBG62976.1 - 0.021 15.3 14.4 0.79 10.3 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 GBG62976.1 - 0.022 15.0 9.2 0.55 10.5 1.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 GBG62976.1 - 0.049 13.9 6.1 1.2 9.4 0.4 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain EPF PF17181.4 GBG62976.1 - 0.088 12.8 5.5 0.26 11.3 0.6 3.0 3 0 0 3 3 3 0 Epidermal patterning factor proteins ETF_QO PF05187.13 GBG62976.1 - 0.089 12.9 5.1 0.53 10.4 0.4 2.4 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 GBG62976.1 - 0.092 13.7 17.4 0.39 11.8 4.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 GBG62976.1 - 0.4 11.6 11.8 2.7 8.9 2.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain TrkH PF02386.16 GBG62979.1 - 0.18 10.2 0.6 0.23 9.8 0.6 1.1 1 0 0 1 1 1 0 Cation transport protein AT_hook PF02178.19 GBG62980.1 - 0.07 13.0 5.8 0.26 11.3 5.8 2.1 1 0 0 1 1 1 0 AT hook motif Mito_carr PF00153.27 GBG62983.1 - 1.1e-27 95.8 0.9 1.3e-16 60.3 0.2 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein RT_RNaseH PF17917.1 GBG62983.1 - 4.4e-24 84.8 0.0 1e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG62983.1 - 5.2e-22 77.8 0.0 1.2e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG62983.1 - 0.043 14.1 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Chromo PF00385.24 GBG62983.1 - 0.093 12.7 1.3 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG62984.1 - 2.8e-29 101.1 0.0 6.4e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG62984.1 - 5.4e-19 68.4 0.2 2.1e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62984.1 - 1.5e-12 47.4 0.8 3.8e-12 46.1 0.8 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Mito_carr PF00153.27 GBG62985.1 - 1.2e-14 53.9 4.8 8.3e-12 44.9 1.1 2.5 2 1 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 GBG62986.1 - 3.1e-12 46.2 1.2 6.7e-12 45.2 1.2 1.6 1 1 0 1 1 1 1 Mitochondrial carrier protein RVT_1 PF00078.27 GBG62987.1 - 8e-31 107.3 0.0 1.7e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG62987.1 - 6.3e-23 80.7 0.0 6.5e-22 77.5 0.0 2.3 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG62987.1 - 1.6e-19 69.7 0.5 3.6e-19 68.6 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62987.1 - 7.7e-15 55.1 0.0 2.2e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG62987.1 - 1.1e-10 41.7 0.0 3e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG62987.1 - 8.3e-08 32.7 0.0 2.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG62987.1 - 3.6e-05 23.9 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG62987.1 - 3.7e-05 24.3 0.0 9.1e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG62987.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG62987.1 - 0.018 14.9 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF1564 PF07600.11 GBG62987.1 - 0.018 14.7 0.0 0.079 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) HepII_C PF18675.1 GBG62987.1 - 0.082 13.0 0.0 24 5.1 0.0 2.7 2 0 0 2 2 2 0 Heparinase II C-terminal domain RVP_2 PF08284.11 GBG62987.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG62988.1 - 3.9e-24 85.4 0.0 7.4e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG62988.1 - 0.00022 21.4 0.2 0.0098 16.2 0.0 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG62988.1 - 0.012 15.5 0.1 0.037 13.9 0.1 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1943 PF09172.11 GBG62989.1 - 0.96 8.6 5.3 1.8 7.7 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) TFIIA PF03153.13 GBG62991.1 - 0.31 11.0 18.3 0.49 10.3 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vps8 PF12816.7 GBG62992.1 - 2.6e-54 183.7 0.0 1.1e-52 178.4 0.0 3.1 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 GBG62992.1 - 2.4e-09 37.2 0.0 3.6e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS WD40 PF00400.32 GBG62992.1 - 0.027 15.3 4.8 0.084 13.8 0.1 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Phage-MuB_C PF09077.11 GBG62992.1 - 0.072 13.0 1.1 0.55 10.2 0.7 2.5 2 0 0 2 2 2 0 Mu B transposition protein, C terminal DUF4914 PF16260.5 GBG62992.1 - 0.12 10.4 0.1 0.18 9.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) YqgF PF14639.6 GBG62992.1 - 0.17 11.6 0.6 0.44 10.3 0.6 1.6 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Integrase_H2C2 PF17921.1 GBG62993.1 - 3.1e-19 68.8 0.1 6.7e-19 67.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG62993.1 - 1.6e-13 50.9 0.0 3.8e-13 49.7 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain IGPD PF00475.18 GBG62993.1 - 0.1 12.9 0.1 5.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase DUF4219 PF13961.6 GBG62994.1 - 0.13 12.0 0.4 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) DsrH PF04077.12 GBG62995.1 - 3.8e-06 26.9 3.1 8.7 6.6 0.0 8.0 2 2 8 10 10 10 4 DsrH like protein Retrotrans_gag PF03732.17 GBG62997.1 - 0.0052 17.0 3.2 0.021 15.1 0.0 3.3 4 1 0 4 4 4 1 Retrotransposon gag protein DUF4373 PF14297.6 GBG62997.1 - 0.0092 16.7 0.1 0.024 15.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4373) Aldo_ket_red PF00248.21 GBG62997.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family DUF4061 PF13270.6 GBG62997.1 - 0.021 15.1 0.6 0.07 13.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) DegS PF05384.11 GBG62997.1 - 0.022 14.2 0.9 0.049 13.1 0.2 1.9 2 0 0 2 2 2 0 Sensor protein DegS DUF3969 PF13108.6 GBG62997.1 - 0.06 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) MazG PF03819.17 GBG62997.1 - 0.078 13.2 0.4 0.4 10.9 0.0 2.4 3 0 0 3 3 3 0 MazG nucleotide pyrophosphohydrolase domain DUF1764 PF08576.10 GBG62997.1 - 0.16 12.9 0.6 0.53 11.2 0.6 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) NOGCT PF08155.11 GBG62997.1 - 0.34 10.9 2.5 3.8 7.6 0.6 2.5 2 0 0 2 2 2 0 NOGCT (NUC087) domain zf-CCHC_4 PF14392.6 GBG62998.1 - 3.4 7.5 7.3 6.3 6.6 7.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Fib_alpha PF08702.10 GBG62999.1 - 0.077 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FliD_C PF07195.12 GBG62999.1 - 0.11 11.9 0.1 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus CdvA PF18822.1 GBG62999.1 - 0.24 11.3 2.6 0.29 11.0 1.2 1.8 2 0 0 2 2 2 0 CdvA-like coiled-coil domain PB1 PF00564.24 GBG63000.1 - 1.6e-15 56.7 0.0 4e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.28 GBG63000.1 - 1.9e-07 30.6 15.8 0.023 14.5 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG63000.1 - 0.00017 21.2 8.0 0.32 10.7 0.5 4.7 6 0 0 6 6 6 2 TPR repeat TPR_2 PF07719.17 GBG63000.1 - 0.00017 21.5 24.6 0.17 12.1 0.1 6.6 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG63000.1 - 0.019 15.2 4.1 13 6.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG63000.1 - 0.089 13.0 3.5 0.28 11.4 2.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG63000.1 - 0.2 12.2 9.1 3.5 8.2 0.2 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG63000.1 - 0.62 10.2 4.1 16 5.8 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG63000.1 - 1.8 9.6 16.0 4.1 8.5 0.9 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG63000.1 - 3.1 8.5 19.6 0.17 12.6 0.6 5.5 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG63000.1 - 6.4 7.1 12.7 9.7 6.6 0.5 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat PB1 PF00564.24 GBG63001.1 - 1.8e-15 56.6 0.0 4e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.28 GBG63001.1 - 1.9e-07 30.6 15.8 0.024 14.5 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG63001.1 - 0.00017 21.4 24.6 0.17 12.0 0.1 6.6 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG63001.1 - 0.00018 21.1 8.0 0.32 10.7 0.5 4.6 6 0 0 6 6 6 2 TPR repeat TPR_8 PF13181.6 GBG63001.1 - 0.019 15.1 4.1 13 6.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG63001.1 - 0.09 12.9 3.5 0.28 11.4 2.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG63001.1 - 0.21 12.1 9.1 3.5 8.2 0.2 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG63001.1 - 0.63 10.2 4.1 16 5.8 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG63001.1 - 1.2 10.1 15.3 4.1 8.5 0.9 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG63001.1 - 2 9.2 18.9 0.17 12.6 0.6 5.4 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG63001.1 - 4.9 7.5 12.3 9.8 6.6 0.5 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Integrase_H2C2 PF17921.1 GBG63002.1 - 9.2e-13 48.1 0.2 2.7e-12 46.6 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63002.1 - 3.9e-11 42.9 0.0 6.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63002.1 - 1e-06 29.0 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG63002.1 - 0.00067 20.2 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63002.1 - 0.0014 19.2 0.0 0.0035 18.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG63002.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG63002.1 - 0.11 12.3 0.7 0.21 11.4 0.7 1.4 1 0 0 1 1 1 0 Aspartyl protease SICA_C PF12879.7 GBG63002.1 - 0.76 9.8 5.1 0.55 10.3 2.0 2.2 2 0 0 2 2 2 0 SICA C-terminal inner membrane domain HMG_box PF00505.19 GBG63003.1 - 7.3e-52 173.7 25.9 3.5e-18 65.8 1.0 4.3 4 0 0 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.10 GBG63003.1 - 1.8e-35 121.4 19.2 6.1e-16 58.8 2.4 5.4 5 1 0 5 5 5 3 HMG-box domain CHDNT PF08073.12 GBG63003.1 - 3.5e-05 23.7 0.4 0.0079 16.1 0.0 3.8 4 0 0 4 4 4 1 CHDNT (NUC034) domain SET PF00856.28 GBG63004.1 - 9.4e-17 61.9 0.8 8.9e-16 58.7 0.1 2.9 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 GBG63004.1 - 1.3e-15 58.0 9.1 1.3e-15 58.0 9.1 2.1 2 0 0 2 2 2 1 Pre-SET motif WIYLD PF10440.9 GBG63004.1 - 0.0002 21.1 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-binding WIYLD domain Nodulin_late PF07127.11 GBG63004.1 - 0.39 11.1 2.0 0.81 10.1 2.0 1.5 1 0 0 1 1 1 0 Late nodulin protein RT_RNaseH_2 PF17919.1 GBG63007.1 - 1.7e-33 114.6 0.0 3.3e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63007.1 - 2.3e-29 101.7 0.1 4.9e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63007.1 - 1.1e-15 57.4 0.1 2.3e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63007.1 - 1.4e-15 57.6 0.0 3.6e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG63007.1 - 0.009 15.7 0.1 0.055 13.2 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) Mcp5_PH PF12814.7 GBG63007.1 - 0.15 12.2 0.5 0.35 11.0 0.5 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology CotJB PF12652.7 GBG63007.1 - 0.16 12.2 0.9 28 5.0 0.1 3.5 3 0 0 3 3 3 0 CotJB protein Rdx PF10262.9 GBG63008.1 - 5.4e-07 29.7 0.0 5.6e-07 29.7 0.0 1.2 1 1 0 1 1 1 1 Rdx family Integrase_H2C2 PF17921.1 GBG63009.1 - 6.2e-13 48.6 0.1 1.5e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63009.1 - 5.4e-11 42.7 0.0 1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG63010.1 - 0.056 13.5 6.4 0.056 13.5 6.4 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG63010.1 - 0.067 13.2 1.0 0.12 12.4 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG63010.1 - 0.81 9.5 3.6 1.6 8.5 3.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1639 PF07797.14 GBG63011.1 - 0.00017 21.5 5.1 0.0014 18.5 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1639) Gon7 PF08738.10 GBG63011.1 - 0.19 11.8 4.9 0.22 11.6 2.4 2.3 1 1 1 2 2 2 0 Gon7 family Pkinase PF00069.25 GBG63012.1 - 1.3e-32 113.2 0.0 7.3e-32 110.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63012.1 - 7.9e-23 81.1 0.0 9.3e-11 41.5 0.0 4.4 4 1 0 4 4 4 2 Protein tyrosine kinase EDR1 PF14381.6 GBG63012.1 - 3.5e-20 72.6 0.0 4.2e-12 46.2 0.0 2.5 2 1 0 2 2 2 2 Ethylene-responsive protein kinase Le-CTR1 LRR_8 PF13855.6 GBG63012.1 - 1.6e-16 59.8 4.6 3.7e-10 39.4 1.8 3.7 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 GBG63012.1 - 2.5e-10 40.4 8.0 4.5e-06 26.9 1.1 4.0 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GBG63012.1 - 0.00018 21.1 0.8 0.00043 19.8 0.3 1.7 2 0 0 2 2 2 1 Leucine-rich repeat Kdo PF06293.14 GBG63012.1 - 0.0021 17.5 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 GBG63012.1 - 0.0035 17.3 3.1 3.2 8.0 0.1 3.8 3 0 0 3 3 3 2 Leucine Rich repeat APH PF01636.23 GBG63012.1 - 0.0097 15.9 0.5 0.84 9.5 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG63012.1 - 0.057 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase LRR_1 PF00560.33 GBG63012.1 - 0.71 10.7 3.7 12 6.9 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat SE PF08491.10 GBG63013.1 - 3.4e-112 374.0 0.0 4.9e-112 373.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 GBG63013.1 - 1.1e-15 57.8 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GBG63013.1 - 1.3e-07 31.6 0.1 0.00014 21.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GBG63013.1 - 3.4e-05 24.0 1.3 9.7e-05 22.5 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GBG63013.1 - 3.8e-05 23.0 1.9 0.00026 20.2 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 GBG63013.1 - 7.7e-05 21.9 0.1 0.00058 19.1 0.1 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GBG63013.1 - 0.00059 19.2 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GBG63013.1 - 0.0014 18.1 0.7 0.0035 16.8 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GBG63013.1 - 0.0019 17.5 0.1 0.0038 16.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 GBG63013.1 - 0.0021 16.8 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 GBG63013.1 - 0.016 14.2 0.1 0.032 13.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 GBG63013.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 GBG63013.1 - 0.15 11.7 0.1 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 GBG63013.1 - 0.26 10.1 0.0 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Voltage_CLC PF00654.20 GBG63014.1 - 7.5e-70 235.9 31.9 2.4e-69 234.3 27.2 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 GBG63014.1 - 2.2e-13 50.4 0.0 1.1e-05 25.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain RPN2_C PF18004.1 GBG63014.1 - 0.016 15.1 5.0 0.029 14.3 5.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 GBG63014.1 - 0.17 11.3 5.2 0.26 10.7 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1673 PF07895.11 GBG63014.1 - 0.23 11.1 0.3 2.3 7.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) NPR3 PF03666.13 GBG63014.1 - 1.9 7.2 3.9 3.2 6.4 3.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 GBG63014.1 - 7.1 4.8 6.1 11 4.2 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 GBG63014.1 - 7.4 6.2 5.1 13 5.4 5.1 1.3 1 0 0 1 1 1 0 Connexin RT_RNaseH PF17917.1 GBG63015.1 - 6.3e-18 65.0 0.0 1.1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63015.1 - 1.6e-17 63.3 0.0 3.2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG63015.1 - 0.0011 19.4 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63015.1 - 0.098 13.3 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG63016.1 - 6.7e-25 87.9 0.0 1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63016.1 - 2.5e-09 37.3 0.0 5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG63016.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Mito_carr PF00153.27 GBG63019.1 - 2.8e-54 181.0 4.5 1.1e-21 76.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HTH_21 PF13276.6 GBG63019.1 - 0.028 14.6 0.2 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 HTH-like domain RT_RNaseH_2 PF17919.1 GBG63020.1 - 4.8e-20 71.4 0.0 1.6e-19 69.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63020.1 - 5.7e-15 55.5 0.9 1.4e-14 54.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG63020.1 - 6.9e-05 23.0 4.4 0.0054 17.0 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_4 PF14392.6 GBG63020.1 - 0.06 13.1 0.2 0.19 11.5 0.2 1.9 1 0 0 1 1 1 0 Zinc knuckle HU-CCDC81_bac_2 PF18175.1 GBG63020.1 - 0.12 12.3 0.4 0.29 11.0 0.4 1.6 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 zf-CCHC_3 PF13917.6 GBG63020.1 - 0.73 9.8 3.6 1.2 9.2 1.6 2.3 2 0 0 2 2 2 0 Zinc knuckle HEAT PF02985.22 GBG63021.1 - 3.2e-14 51.8 4.5 0.0064 16.6 0.3 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 GBG63021.1 - 1e-06 29.0 0.7 0.1 13.0 0.1 3.6 2 1 0 2 2 2 2 HEAT repeats LisH PF08513.11 GBG63021.1 - 1.4e-05 24.8 0.7 0.002 18.0 0.0 2.7 2 0 0 2 2 2 2 LisH HEAT_EZ PF13513.6 GBG63021.1 - 1.5e-05 25.4 1.8 0.0068 16.9 0.1 4.1 2 1 1 3 3 3 1 HEAT-like repeat KN17_SH3 PF18131.1 GBG63022.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 KN17 SH3-like C-terminal domain Syntaxin PF00804.25 GBG63023.1 - 8.3e-52 175.8 11.4 1e-51 175.5 11.4 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 GBG63023.1 - 9e-14 51.2 0.4 9e-14 51.2 0.4 1.8 2 0 0 2 2 2 1 SNARE domain DUF3543 PF12063.8 GBG63023.1 - 0.016 14.6 0.6 0.016 14.6 0.6 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3543) Snf7 PF03357.21 GBG63023.1 - 0.018 14.6 8.2 0.032 13.8 8.2 1.3 1 0 0 1 1 1 0 Snf7 TRPM_tetra PF16519.5 GBG63023.1 - 0.029 14.5 0.4 0.029 14.5 0.4 2.3 3 0 0 3 3 3 0 Tetramerisation domain of TRPM PSCyt2 PF07583.11 GBG63023.1 - 0.03 14.3 0.1 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) Syntaxin_2 PF14523.6 GBG63023.1 - 0.063 13.6 3.1 0.12 12.8 0.7 2.4 2 2 0 2 2 2 0 Syntaxin-like protein SesA PF17107.5 GBG63023.1 - 0.068 13.4 2.2 0.14 12.4 0.4 2.3 1 1 2 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sulfatase_C PF14707.6 GBG63023.1 - 0.087 13.6 0.4 0.26 12.0 0.0 1.9 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Baculo_PEP_C PF04513.12 GBG63023.1 - 0.18 11.8 1.5 0.3 11.1 0.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 GBG63023.1 - 0.44 11.1 6.8 0.26 11.8 1.6 2.9 2 2 0 2 2 2 0 Spectrin repeat UPF0154 PF03672.13 GBG63023.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.9 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0154) EMP24_GP25L PF01105.24 GBG63023.1 - 2 8.3 11.2 1.7 8.5 3.1 2.9 2 2 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2203 PF09969.9 GBG63023.1 - 5.3 7.8 7.2 12 6.6 0.7 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) RRM_1 PF00076.22 GBG63024.1 - 5.2e-10 39.0 0.0 7.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG63024.1 - 0.026 14.6 0.0 0.039 14.1 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif Myb_DNA-bind_4 PF13837.6 GBG63025.1 - 5.3e-09 36.3 0.9 1.1e-08 35.4 0.9 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG63025.1 - 0.0026 17.8 1.6 0.0026 17.8 1.6 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG63026.1 - 2.8e-09 37.2 0.9 5.7e-09 36.2 0.9 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG63026.1 - 0.0015 18.5 1.6 0.0015 18.5 1.6 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Aldo_ket_red PF00248.21 GBG63027.1 - 1.1e-44 152.8 0.0 1.5e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BUD22 PF09073.10 GBG63028.1 - 0.0057 16.0 16.1 0.0087 15.5 16.1 1.2 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 GBG63028.1 - 0.036 12.4 10.7 0.056 11.7 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 GBG63028.1 - 0.33 10.5 11.0 11 5.6 12.0 2.1 2 0 0 2 2 2 0 PPP4R2 Presenilin PF01080.17 GBG63028.1 - 9.1 4.9 6.5 12 4.5 6.5 1.2 1 0 0 1 1 1 0 Presenilin MitMem_reg PF13012.6 GBG63030.1 - 3.6e-38 130.4 0.8 5.5e-38 129.8 0.8 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GBG63030.1 - 1.6e-29 102.3 0.0 2.8e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RQC PF09382.10 GBG63031.1 - 3.4e-24 84.8 0.8 6.9e-24 83.8 0.8 1.5 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 GBG63031.1 - 9.4e-18 64.6 0.0 4e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GBG63031.1 - 2.4e-17 63.4 2.9 6.9e-17 61.9 2.9 1.9 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 GBG63031.1 - 6.4e-17 61.9 0.0 1.4e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HRDC PF00570.23 GBG63031.1 - 7.7e-14 51.4 0.0 2.6e-13 49.7 0.0 2.0 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 GBG63031.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SopD PF11047.8 GBG63032.1 - 0.039 13.1 0.5 0.077 12.2 0.5 1.4 1 0 0 1 1 1 0 Salmonella outer protein D TPK_catalytic PF04263.16 GBG63033.1 - 1.8e-05 24.7 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain rve PF00665.26 GBG63034.1 - 2.5e-27 95.4 0.1 7.2e-16 58.4 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG63034.1 - 4.2e-26 90.9 0.0 3.1e-25 88.1 0.0 2.6 3 0 0 3 3 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63034.1 - 6.4e-25 88.0 0.0 1.3e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63034.1 - 1.6e-23 83.0 0.0 5.1e-23 81.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63034.1 - 7.6e-19 67.6 0.3 2.1e-18 66.2 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG63034.1 - 1.5e-07 31.8 0.0 3.8e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63034.1 - 2e-07 31.5 0.0 4.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG63034.1 - 3.5e-06 26.8 0.1 0.054 13.4 0.0 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG63034.1 - 5.9e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63034.1 - 7e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DNA_pack_N PF02500.15 GBG63034.1 - 0.016 15.1 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 1 0 Probable DNA packing protein, N-terminus rve_3 PF13683.6 GBG63034.1 - 0.076 12.8 0.1 3.3 7.5 0.0 3.0 2 0 0 2 2 2 0 Integrase core domain Retrotrans_gag PF03732.17 GBG63034.1 - 7.5 6.9 7.1 2.8 8.3 0.0 3.9 4 0 0 4 4 3 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG63035.1 - 2.4e-26 91.7 0.0 1.9e-25 88.8 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63035.1 - 4.4e-25 88.5 0.0 7.9e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63035.1 - 9.5e-24 83.7 0.0 3.1e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63035.1 - 4.7e-19 68.3 0.3 1.3e-18 66.8 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63035.1 - 4.6e-09 36.5 0.0 1.7e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG63035.1 - 9.3e-08 32.5 0.0 2.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63035.1 - 1.2e-07 32.2 0.0 2.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63035.1 - 3.5e-06 26.8 0.0 7.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63035.1 - 4.6e-05 23.2 0.0 8.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG63035.1 - 0.011 15.6 0.0 0.034 14.1 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG63035.1 - 0.064 13.5 0.1 1.8 8.9 0.0 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein TPK_catalytic PF04263.16 GBG63036.1 - 1.1e-29 102.8 0.0 2.1e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 GBG63036.1 - 1.2e-14 53.7 0.1 2.7e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF1564 PF07600.11 GBG63036.1 - 0.022 14.4 0.0 0.08 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) rve PF00665.26 GBG63036.1 - 0.097 12.9 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain rve_3 PF13683.6 GBG63036.1 - 0.14 11.9 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain BUD22 PF09073.10 GBG63037.1 - 0.31 10.4 24.2 0.37 10.1 24.2 1.1 1 0 0 1 1 1 0 BUD22 Sec62 PF03839.16 GBG63037.1 - 1.1 8.7 11.5 1.5 8.3 11.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 GBG63037.1 - 1.1 7.9 13.1 1.1 7.9 13.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 GBG63037.1 - 1.6 7.8 7.6 1.8 7.7 7.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RabGAP-TBC PF00566.18 GBG63037.1 - 1.8 8.2 7.0 2.5 7.7 7.0 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Peptidase_S64 PF08192.11 GBG63037.1 - 2.7 6.4 7.5 2.9 6.3 7.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 FAM60A PF15396.6 GBG63037.1 - 3 7.8 8.5 3.4 7.6 8.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Sporozoite_P67 PF05642.11 GBG63037.1 - 3 5.8 11.0 3.4 5.6 11.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HSP70 PF00012.20 GBG63037.1 - 4 5.5 15.8 4.3 5.4 15.8 1.1 1 0 0 1 1 1 0 Hsp70 protein MDM10 PF12519.8 GBG63037.1 - 5.1 5.8 7.1 5.3 5.8 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PA26 PF04636.13 GBG63037.1 - 7.1 5.4 8.3 7 5.4 8.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RT_RNaseH_2 PF17919.1 GBG63038.1 - 5.6e-29 100.1 0.0 8.9e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63038.1 - 9.4e-28 96.6 0.0 1.4e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG63038.1 - 0.0037 17.2 2.3 0.0077 16.2 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle TetR_C_20 PF17925.1 GBG63038.1 - 0.036 14.4 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain BUD22 PF09073.10 GBG63039.1 - 0.028 13.8 19.9 0.038 13.3 19.9 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG63039.1 - 0.24 10.8 24.7 0.31 10.4 24.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG63039.1 - 2.1 6.5 27.4 2.7 6.1 27.4 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG63039.1 - 2.6 7.8 12.0 4.4 7.0 12.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 GBG63039.1 - 3.1 6.3 26.0 4.1 5.9 26.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LAP1C PF05609.12 GBG63039.1 - 3.3 6.7 9.6 4.1 6.4 9.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG63040.1 - 0.045 12.0 12.5 0.089 11.0 12.5 1.4 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.23 GBG63041.1 - 0.0045 17.0 1.9 0.0076 16.3 1.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG63041.1 - 0.11 12.3 0.9 0.27 11.0 0.9 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG63041.1 - 0.16 11.7 1.2 0.46 10.3 1.2 1.8 1 0 0 1 1 1 0 Zinc knuckle FinO_N PF12602.8 GBG63041.1 - 0.75 10.2 6.3 6.8 7.1 0.0 3.2 3 0 0 3 3 3 0 Fertility inhibition protein N terminal OmpH PF03938.14 GBG63041.1 - 5.3 7.4 19.0 0.25 11.7 5.5 3.2 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Syntaxin_2 PF14523.6 GBG63041.1 - 6.9 7.1 10.9 11 6.4 0.1 3.9 3 1 0 3 3 3 0 Syntaxin-like protein RT_RNaseH_2 PF17919.1 GBG63042.1 - 1.1e-31 108.9 0.0 2.4e-16 59.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63042.1 - 6.8e-30 103.5 0.0 1.3e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63042.1 - 3.5e-29 101.9 0.1 6.6e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Annexin PF00191.20 GBG63043.1 - 4.1e-46 154.9 2.2 5.1e-13 48.9 0.1 4.6 5 0 0 5 5 5 4 Annexin DUF4611 PF15387.6 GBG63043.1 - 0.074 13.3 2.1 0.23 11.7 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RT_RNaseH_2 PF17919.1 GBG63045.1 - 5.4e-31 106.6 0.1 1.1e-30 105.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63045.1 - 1e-27 96.5 0.4 2.2e-27 95.4 0.4 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63045.1 - 1.7e-14 53.9 0.9 2.1e-12 47.0 0.3 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) SHR-BD PF06650.12 GBG63045.1 - 1.4e-13 50.9 0.0 7.9e-13 48.4 0.0 2.3 1 1 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 gag-asp_proteas PF13975.6 GBG63045.1 - 1.4e-06 28.8 0.0 3.9e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63045.1 - 0.0003 21.3 0.0 0.0008 20.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease SDA1 PF05285.12 GBG63045.1 - 0.0011 18.5 62.7 0.11 11.8 36.5 2.7 2 0 0 2 2 2 2 SDA1 RVP_2 PF08284.11 GBG63045.1 - 0.032 14.0 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.12 GBG63045.1 - 0.035 13.9 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) rve PF00665.26 GBG63046.1 - 8.8e-11 42.0 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain XRN_M PF17846.1 GBG63046.1 - 0.29 10.0 3.2 0.5 9.3 3.2 1.4 1 0 0 1 1 1 0 Xrn1 helical domain SAPS PF04499.15 GBG63046.1 - 1.8 7.3 10.1 2.7 6.7 10.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GBG63046.1 - 4.2 6.0 16.8 0.19 10.4 10.9 1.7 2 0 0 2 2 2 0 Presenilin Chromo PF00385.24 GBG63047.1 - 0.006 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CPP1-like PF11833.8 GBG63047.1 - 0.094 12.4 0.7 0.18 11.5 0.7 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3640 PF12342.8 GBG63047.1 - 0.14 11.9 0.4 11 5.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3640) RVT_1 PF00078.27 GBG63048.1 - 1.7e-24 86.6 0.0 2.4e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63049.1 - 2.4e-22 78.8 0.0 4.2e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63049.1 - 1.4e-18 67.1 0.0 2.4e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG63049.1 - 0.0024 17.7 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NYD-SP28_assoc PF14775.6 GBG63050.1 - 0.37 10.9 4.9 16 5.7 0.6 3.5 3 0 0 3 3 3 0 Sperm tail C-terminal domain RT_RNaseH_2 PF17919.1 GBG63051.1 - 2.4e-25 88.4 0.0 5.9e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63051.1 - 4.7e-20 72.1 0.0 8.9e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63051.1 - 4.7e-19 68.6 0.0 1.4e-18 67.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Trypan_PARP PF05887.11 GBG63051.1 - 0.00015 21.7 15.4 0.00031 20.7 15.4 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) RVP_2 PF08284.11 GBG63051.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG63051.1 - 0.021 15.1 0.3 0.18 12.1 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Caudo_TAP PF02413.17 GBG63051.1 - 1.6 8.9 10.4 0.42 10.7 1.7 2.7 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK CDH1_2_SANT_HL1 PF18375.1 GBG63051.1 - 3 8.6 4.3 7.7 7.3 0.0 2.9 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 RT_RNaseH_2 PF17919.1 GBG63052.1 - 3.7e-66 219.4 0.0 5.7e-25 87.3 0.0 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63052.1 - 2.6e-58 197.2 1.1 5.2e-27 94.8 0.0 3.4 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63052.1 - 4.2e-44 149.1 0.0 1.7e-21 76.5 0.0 3.9 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG63052.1 - 1.2e-06 28.3 0.0 0.29 10.9 0.0 3.4 3 0 0 3 3 3 2 Retroviral aspartyl protease TMEM247 PF15444.6 GBG63052.1 - 0.01 15.9 0.1 0.034 14.2 0.1 1.9 1 0 0 1 1 1 0 Transmembrane protein 247 Retrotrans_gag PF03732.17 GBG63052.1 - 0.025 14.8 0.1 0.16 12.3 0.1 2.5 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG63053.1 - 1.3e-09 37.9 0.0 2.7e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CRT10 PF08728.10 GBG63054.1 - 0.61 8.2 6.6 0.87 7.7 6.6 1.2 1 0 0 1 1 1 0 CRT10 DUF4167 PF13763.6 GBG63055.1 - 0.0038 17.3 1.8 0.0038 17.3 1.8 7.1 4 1 0 4 4 4 1 Domain of unknown function (DUF4167) Hamartin PF04388.12 GBG63055.1 - 5.2 5.6 14.5 7 5.2 14.5 1.2 1 0 0 1 1 1 0 Hamartin protein RVT_1 PF00078.27 GBG63058.1 - 8.9e-09 35.2 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG63058.1 - 2.2e-06 28.2 0.0 5.4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63058.1 - 0.00013 22.5 0.0 0.00041 20.9 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63058.1 - 0.00075 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG63058.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Kinesin PF00225.23 GBG63059.1 - 9.7e-108 360.0 0.0 1.7e-107 359.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG63059.1 - 3.4e-44 150.4 0.0 6.4e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding CH PF00307.31 GBG63059.1 - 2.1e-12 47.2 0.0 1.3e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain SpoIIE PF07228.12 GBG63059.1 - 2.5 8.0 5.1 2 8.3 0.1 2.9 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Kinesin PF00225.23 GBG63060.1 - 9.6e-108 360.0 0.0 1.7e-107 359.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG63060.1 - 3.3e-44 150.4 0.0 6.3e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding CH PF00307.31 GBG63060.1 - 2e-12 47.2 0.0 1.2e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain SpoIIE PF07228.12 GBG63060.1 - 2.8 7.8 5.3 2 8.3 0.1 2.9 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Kinesin PF00225.23 GBG63061.1 - 9.6e-108 360.0 0.0 1.7e-107 359.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG63061.1 - 3.3e-44 150.4 0.0 6.3e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding CH PF00307.31 GBG63061.1 - 2e-12 47.2 0.0 1.2e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain SpoIIE PF07228.12 GBG63061.1 - 2.8 7.8 5.3 2 8.3 0.1 2.9 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) E1_DerP2_DerF2 PF02221.15 GBG63063.1 - 1.2e-10 41.9 0.0 1.4e-10 41.8 0.0 1.0 1 0 0 1 1 1 1 ML domain Integrase_H2C2 PF17921.1 GBG63065.1 - 6.1e-15 55.1 0.1 1.2e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG63065.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63065.1 - 0.17 12.2 0.0 0.43 10.9 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase NPR3 PF03666.13 GBG63065.1 - 0.63 8.8 2.4 1 8.1 2.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PRTP PF01366.18 GBG63065.1 - 0.88 7.5 2.9 1.5 6.8 2.9 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Integrase_H2C2 PF17921.1 GBG63066.1 - 5.5e-15 55.2 0.1 1.1e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG63066.1 - 0.0011 19.0 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63066.1 - 0.16 12.3 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase NPR3 PF03666.13 GBG63066.1 - 0.64 8.7 2.5 0.98 8.1 2.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PRTP PF01366.18 GBG63066.1 - 0.81 7.7 2.9 1.4 6.9 2.9 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein FGF-BP1 PF06473.12 GBG63066.1 - 2.5 7.9 6.9 5.6 6.7 6.9 1.5 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) BUD22 PF09073.10 GBG63067.1 - 0.14 11.5 10.3 0.15 11.4 10.3 1.0 1 0 0 1 1 1 0 BUD22 U1snRNP70_N PF12220.8 GBG63067.1 - 1.6 9.5 6.3 2.2 9.0 6.3 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Aminotran_1_2 PF00155.21 GBG63068.1 - 1.8e-60 205.0 0.0 2.1e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GBG63068.1 - 0.00015 20.9 0.0 0.00029 19.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GBG63068.1 - 0.004 16.5 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GBG63068.1 - 0.013 14.0 0.0 0.023 13.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 GBG63068.1 - 0.073 11.6 0.0 0.19 10.2 0.0 1.6 2 0 0 2 2 2 0 Methionine gamma-lyase Beta_elim_lyase PF01212.21 GBG63068.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase TRAF6_Z2 PF18048.1 GBG63069.1 - 0.14 12.3 2.0 0.3 11.2 0.2 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 RT_RNaseH_2 PF17919.1 GBG63070.1 - 1e-33 115.3 0.0 2.5e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63070.1 - 6.6e-31 107.5 0.1 1.3e-30 106.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63070.1 - 6.1e-28 97.2 0.1 1.2e-27 96.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63070.1 - 7.4e-19 67.6 0.3 1.7e-18 66.5 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63070.1 - 2.8e-05 24.3 0.0 7.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63070.1 - 0.00052 20.2 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG63071.1 - 1.1e-29 103.6 0.0 1.7e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63071.1 - 8.7e-27 93.1 0.0 2.6e-26 91.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63071.1 - 3.6e-16 59.4 0.0 1.1e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG63071.1 - 5.6e-07 30.1 0.0 1.3e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63071.1 - 6.8e-07 29.8 0.0 1.6e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63071.1 - 2.7e-06 27.2 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG63071.1 - 2e-05 24.8 0.0 7.8e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG63071.1 - 0.00026 20.8 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG63071.1 - 0.0041 17.0 0.1 0.0089 15.9 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG63071.1 - 0.046 14.0 0.5 0.22 11.8 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein SelP_N PF04592.14 GBG63072.1 - 0.4 10.0 5.4 0.74 9.2 5.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pyr_redox_2 PF07992.14 GBG63073.1 - 1.4e-54 185.4 0.1 1.8e-54 185.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG63073.1 - 1.4e-21 76.8 1.0 1e-19 70.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG63073.1 - 1.3e-10 41.0 0.0 4.8e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG63073.1 - 0.0001 21.2 0.5 0.0039 15.9 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.6 GBG63073.1 - 0.00044 19.5 0.0 0.0025 17.0 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 GBG63073.1 - 0.0019 17.5 0.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GBG63073.1 - 0.011 15.1 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 GBG63073.1 - 0.06 12.6 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 GBG63073.1 - 0.56 9.2 3.4 2.2 7.3 3.1 2.1 3 0 0 3 3 3 0 FAD binding domain RVT_1 PF00078.27 GBG63074.1 - 2.2e-37 128.7 0.1 3.5e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4392 PF14336.6 GBG63074.1 - 0.038 13.4 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Sirohm_synth_M PF14824.6 GBG63074.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Pyr_redox_dim PF02852.22 GBG63075.1 - 4.7e-21 75.1 0.4 5.3e-21 74.9 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain YbjN PF10722.9 GBG63075.1 - 0.0069 16.4 0.0 0.0086 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator zf-CCHC PF00098.23 GBG63076.1 - 1.1e-07 31.6 16.6 0.00015 21.6 3.3 3.0 3 0 0 3 3 3 2 Zinc knuckle Cwf_Cwc_15 PF04889.12 GBG63076.1 - 0.027 14.2 2.6 0.047 13.4 2.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-CCHC_3 PF13917.6 GBG63076.1 - 0.34 10.9 10.5 1.2 9.1 3.2 2.5 1 1 1 2 2 2 0 Zinc knuckle Zn_Tnp_IS91 PF14319.6 GBG63076.1 - 5.2 7.2 10.6 12 6.0 10.6 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC PF00098.23 GBG63078.1 - 4.3e-07 29.7 3.6 1.5e-06 28.0 3.6 2.0 1 0 0 1 1 1 1 Zinc knuckle GIY-YIG PF01541.24 GBG63078.1 - 6.6e-07 29.5 0.0 3.1e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 GIY-YIG catalytic domain zf-CCHC_5 PF14787.6 GBG63078.1 - 0.024 14.3 0.9 0.07 12.9 0.9 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF1772 PF08592.11 GBG63079.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DDE_Tnp_4 PF13359.6 GBG63080.1 - 1.2e-18 67.2 0.0 2.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63080.1 - 8.2e-08 32.1 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG63080.1 - 0.032 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Nop14 PF04147.12 GBG63081.1 - 1.7 6.8 16.1 3 6.0 16.1 1.3 1 0 0 1 1 1 0 Nop14-like family Nop14 PF04147.12 GBG63082.1 - 0.062 11.5 15.4 0.09 11.0 15.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG63082.1 - 0.19 9.9 10.7 0.28 9.4 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG63082.1 - 0.26 9.3 21.8 0.36 8.9 21.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG63082.1 - 0.37 10.2 15.1 0.55 9.6 15.1 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG63082.1 - 1.2 8.4 13.2 1.9 7.8 13.2 1.3 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 GBG63082.1 - 1.9 8.2 8.2 6.1 6.5 8.2 1.9 1 0 0 1 1 1 0 FAM176 family RVT_1 PF00078.27 GBG63083.1 - 4.9e-35 121.1 0.0 9.6e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63083.1 - 1.2e-30 105.4 0.0 4.5e-30 103.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63083.1 - 1.8e-29 102.1 0.0 3.5e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG63083.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG63084.1 - 1.8e-27 95.3 0.0 3e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63084.1 - 7.8e-21 74.3 0.0 1.3e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63084.1 - 6e-10 39.0 0.1 9.7e-10 38.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG63085.1 - 6.5e-29 100.6 0.0 1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63085.1 - 3.3e-12 46.4 0.0 4.8e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG63085.1 - 0.00074 19.2 0.2 0.062 12.9 0.0 2.4 2 1 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG63086.1 - 0.0003 21.1 5.0 0.00031 21.0 2.9 2.1 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 GBG63087.1 - 0.034 14.4 0.4 0.56 10.5 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein CorA PF01544.18 GBG63087.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2730 PF10805.8 GBG63087.1 - 0.11 12.6 0.2 0.54 10.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Cast PF10174.9 GBG63087.1 - 0.18 10.0 3.3 0.27 9.4 3.3 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone SlyX PF04102.12 GBG63087.1 - 0.37 11.4 8.1 0.16 12.6 1.3 2.9 1 1 1 2 2 2 0 SlyX TPX2 PF06886.11 GBG63089.1 - 5e-05 23.5 1.4 5e-05 23.5 1.4 2.6 2 0 0 2 2 2 2 Targeting protein for Xklp2 (TPX2) RT_RNaseH_2 PF17919.1 GBG63092.1 - 5.6e-14 52.0 0.0 2.3e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63092.1 - 5.5e-13 49.1 0.0 7.4e-12 45.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63092.1 - 9.2e-13 48.4 0.0 3.6e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG63092.1 - 9.7e-07 29.3 0.0 2.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG63092.1 - 2.8e-05 23.7 0.0 5.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG63092.1 - 0.00035 21.2 0.0 0.00083 19.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG63092.1 - 0.0082 15.9 0.5 0.016 15.0 0.5 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG63092.1 - 0.039 14.3 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Casc1_N PF15927.5 GBG63093.1 - 5.6e-37 127.4 16.0 5.6e-37 127.4 16.0 2.6 2 1 1 3 3 3 1 Cancer susceptibility candidate 1 N-terminus Trypsin PF00089.26 GBG63093.1 - 6.4e-06 26.1 0.1 1.5e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Trypsin Spore_coat_CotO PF14153.6 GBG63093.1 - 3.3 7.6 12.3 8.7 6.2 12.3 1.6 1 0 0 1 1 1 0 Spore coat protein CotO RT_RNaseH_2 PF17919.1 GBG63094.1 - 2.5e-31 107.7 0.1 4.8e-31 106.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63094.1 - 3.6e-28 97.9 0.1 7.4e-28 96.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63094.1 - 8.4e-20 70.6 0.1 2.2e-19 69.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG63094.1 - 0.018 15.2 0.0 0.098 12.9 0.0 2.3 2 0 0 2 2 2 0 H2C2 zinc finger Sporozoite_P67 PF05642.11 GBG63094.1 - 0.16 10.0 1.3 0.24 9.4 1.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC1 PF03109.16 GBG63095.1 - 1.2e-22 80.3 0.0 2.5e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GBG63095.1 - 0.00013 21.9 0.6 0.0016 18.4 0.3 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 GBG63095.1 - 0.0029 17.0 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ICL PF00463.21 GBG63096.1 - 0.15 10.6 4.3 0.54 8.7 0.5 2.1 1 1 1 2 2 2 0 Isocitrate lyase family SeleniumBinding PF11524.8 GBG63096.1 - 0.77 10.2 8.0 4.9 7.7 0.5 4.1 1 1 2 3 3 3 0 Selenium binding protein Elong-fact-P_C PF09285.11 GBG63096.1 - 0.92 9.3 5.6 20 5.0 0.2 3.5 3 2 0 3 3 3 0 Elongation factor P, C-terminal PBSX_XtrA PF17356.2 GBG63096.1 - 1.3 9.0 12.1 2.4 8.1 0.2 4.2 2 1 2 4 4 4 0 Phage-like element PBSX protein XtrA DUF659 PF04937.15 GBG63097.1 - 2.7e-12 46.8 0.0 4.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63097.1 - 0.0039 17.0 0.0 0.0086 15.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Mito_fiss_reg PF05308.11 GBG63097.1 - 7.5 6.6 8.0 5.8 6.9 3.5 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase PF00069.25 GBG63098.1 - 1.1e-71 241.3 0.1 2.4e-71 240.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63098.1 - 6.4e-47 160.0 0.0 1.2e-46 159.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GBG63098.1 - 0.0021 17.5 0.0 0.0021 17.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG63098.1 - 0.009 15.9 0.1 0.009 15.9 0.1 2.7 1 1 2 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GBG63098.1 - 0.017 14.6 3.8 0.35 10.4 0.0 2.2 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 GBG63098.1 - 0.063 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TFIIA PF03153.13 GBG63098.1 - 5.5 6.9 17.4 0.092 12.7 9.8 1.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit TPR_10 PF13374.6 GBG63100.1 - 0.18 11.7 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3543 PF12063.8 GBG63103.1 - 2.6e-05 23.7 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) NPR3 PF03666.13 GBG63103.1 - 0.044 12.6 4.9 0.048 12.4 4.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GBG63103.1 - 0.19 10.5 3.3 0.22 10.2 3.3 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GBG63103.1 - 0.19 10.9 0.4 0.19 10.9 0.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RVT_1 PF00078.27 GBG63105.1 - 1.7e-26 93.1 0.0 3.1e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63105.1 - 7.2e-24 83.7 0.0 2.4e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63105.1 - 1.4e-23 83.1 0.0 3.1e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pyr_redox_2 PF07992.14 GBG63105.1 - 1.2e-19 70.6 0.1 2.1e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Arm PF00514.23 GBG63105.1 - 1.8e-15 56.4 2.0 0.00019 21.4 0.0 5.8 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Pyr_redox PF00070.27 GBG63105.1 - 1.1e-12 48.4 0.0 2.7e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase U-box PF04564.15 GBG63105.1 - 1.9e-09 37.5 0.0 5e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GBG63105.1 - 7.4e-05 22.5 0.1 0.00017 21.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Retrotrans_gag PF03732.17 GBG63105.1 - 0.00044 20.5 0.0 0.0022 18.3 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Arm_2 PF04826.13 GBG63105.1 - 0.0014 18.2 0.0 0.0056 16.2 0.0 2.0 2 0 0 2 2 2 1 Armadillo-like DUF1543 PF07566.12 GBG63105.1 - 0.15 11.8 0.4 4.9 7.0 0.0 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1543) HEAT PF02985.22 GBG63105.1 - 4.1 7.9 5.7 53 4.5 0.0 4.1 4 0 0 4 4 3 0 HEAT repeat DUF3138 PF11336.8 GBG63106.1 - 0.07 11.7 3.1 0.085 11.5 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3500 PF12006.8 GBG63106.1 - 1.3 8.4 4.9 1.4 8.3 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3500) DUF3629 PF12302.8 GBG63106.1 - 2.2 7.6 7.9 3.6 7.0 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Herpes_UL25 PF01499.16 GBG63106.1 - 3.5 6.0 7.5 4.8 5.6 7.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family TMPIT PF07851.13 GBG63106.1 - 9.8 5.3 7.6 11 5.2 7.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Taxilin PF09728.9 GBG63107.1 - 0.028 13.6 35.3 0.042 13.0 35.3 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein RVT_1 PF00078.27 GBG63108.1 - 5.5e-11 42.4 0.0 9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_carr PF00153.27 GBG63109.1 - 9.4e-75 246.6 0.1 2.6e-25 88.2 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GBG63109.1 - 0.065 12.4 0.1 14 4.8 0.0 3.3 2 1 1 3 3 3 0 Gammaproteobacterial serine protease rve PF00665.26 GBG63112.1 - 5.3e-07 29.9 0.0 2e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Herpes_BLRF2 PF05812.12 GBG63117.1 - 5.8e-05 23.2 0.5 5.8e-05 23.2 0.5 2.5 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein Atg14 PF10186.9 GBG63117.1 - 0.012 14.7 0.6 0.012 14.7 0.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CorA PF01544.18 GBG63117.1 - 0.022 14.1 0.4 0.022 14.1 0.4 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein D123 PF07065.14 GBG63117.1 - 0.36 9.9 3.7 0.59 9.2 3.7 1.3 1 0 0 1 1 1 0 D123 DUF612 PF04747.12 GBG63117.1 - 0.4 9.7 14.0 0.48 9.5 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Presenilin PF01080.17 GBG63118.1 - 0.013 14.3 14.7 0.51 9.1 0.3 2.3 2 0 0 2 2 2 0 Presenilin Gti1_Pac2 PF09729.9 GBG63118.1 - 5.4 7.1 13.9 9.8 6.2 0.0 2.6 2 1 0 2 2 2 0 Gti1/Pac2 family RT_RNaseH_2 PF17919.1 GBG63121.1 - 4.1e-26 90.9 0.0 6.7e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63121.1 - 1.7e-23 82.9 0.0 2.9e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63121.1 - 0.016 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG63121.1 - 0.019 15.0 0.2 0.043 13.9 0.2 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain Trans_reg_C PF00486.28 GBG63123.1 - 0.073 13.2 0.4 0.19 11.8 0.4 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal UPF0184 PF03670.13 GBG63123.1 - 0.4 11.1 3.5 2 8.8 0.1 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) NOG1_N PF17835.1 GBG63123.1 - 0.66 9.9 5.3 0.92 9.5 4.0 1.9 2 0 0 2 2 2 0 NOG1 N-terminal helical domain DUF4559 PF15112.6 GBG63123.1 - 1.7 8.3 8.0 1.3 8.6 5.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) NifQ PF04891.12 GBG63123.1 - 4.2 7.7 5.5 1.6 9.1 0.9 2.5 2 1 1 3 3 3 0 NifQ MscS_porin PF12795.7 GBG63123.1 - 6.5 6.2 16.0 0.51 9.8 11.3 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Nexin_C PF08628.12 GBG63123.1 - 6.5 7.4 7.4 8.1 7.1 1.9 2.9 1 1 1 2 2 2 0 Sorting nexin C terminal SAPS PF04499.15 GBG63124.1 - 4.1 6.1 6.8 4.4 6.0 6.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RVT_1 PF00078.27 GBG63126.1 - 1.9e-33 115.8 0.0 3e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3023 PF11224.8 GBG63126.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) zf-CCHC PF00098.23 GBG63127.1 - 2.6e-07 30.4 3.8 4.9e-07 29.5 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle TAF4 PF05236.14 GBG63127.1 - 0.019 14.8 7.2 0.03 14.1 7.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family MAJIN PF15077.6 GBG63127.1 - 0.38 10.5 3.3 0.52 10.1 3.3 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein DNA_pol3_a_NII PF11490.8 GBG63127.1 - 0.82 9.6 9.6 1.3 8.9 9.6 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II RVT_1 PF00078.27 GBG63128.1 - 2.4e-11 43.6 0.1 0.0022 17.5 0.0 4.1 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) MlaD PF02470.20 GBG63128.1 - 0.11 12.8 0.1 30 5.0 0.0 2.5 2 0 0 2 2 2 0 MlaD protein RVT_1 PF00078.27 GBG63129.1 - 1.3e-17 64.1 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG63130.1 - 5.7e-20 71.8 0.0 8.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63130.1 - 2e-14 53.5 0.0 3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG63130.1 - 0.096 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 GBG63131.1 - 5.7e-20 71.8 0.0 8.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63131.1 - 2e-14 53.5 0.0 3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG63131.1 - 0.096 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Asp_protease PF09668.10 GBG63132.1 - 6.4e-58 193.9 0.0 8.6e-58 193.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63132.1 - 4.2e-18 65.7 0.0 9.2e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.31 GBG63132.1 - 6.3e-08 32.4 0.1 1.3e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Asp_protease_2 PF13650.6 GBG63132.1 - 9.6e-07 29.4 0.0 2.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG63132.1 - 0.029 14.7 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 GBG63132.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease KleE PF17394.2 GBG63132.1 - 0.14 12.3 0.4 0.29 11.4 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein TEBP_beta PF07404.11 GBG63132.1 - 0.22 10.8 3.4 0.33 10.3 3.4 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) DUF737 PF05300.11 GBG63132.1 - 3.2 8.1 5.3 0.73 10.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF737) TRAPPC9-Trs120 PF08626.11 GBG63133.1 - 1.3e-53 181.8 0.0 8e-19 66.6 0.0 3.3 2 1 1 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC9-Trs120 PF08626.11 GBG63134.1 - 1.3e-53 181.8 0.0 8e-19 66.6 0.0 3.3 2 1 1 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ribosomal_L18 PF17135.4 GBG63136.1 - 4.4e-70 234.9 0.2 4.9e-70 234.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 GBG63136.1 - 0.025 15.3 0.0 0.13 12.9 0.0 2.1 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF3419 PF11899.8 GBG63137.1 - 1.8e-103 346.7 0.0 1.3e-59 202.4 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3419) PPS_PS PF02006.16 GBG63137.1 - 0.088 12.4 0.1 4.4 6.8 0.1 2.2 2 0 0 2 2 2 0 Phosphopantothenate/pantothenate synthetase GLYCAM-1 PF05242.11 GBG63139.1 - 0.031 14.4 0.8 0.062 13.4 0.8 1.4 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) RT_RNaseH_2 PF17919.1 GBG63140.1 - 3.4e-24 84.8 0.0 6.5e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63140.1 - 6.2e-23 81.1 0.0 1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63140.1 - 3.3e-07 30.0 0.1 5.2e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3807 PF12720.7 GBG63140.1 - 0.11 12.7 13.6 0.16 12.2 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Nop14 PF04147.12 GBG63140.1 - 2 6.6 23.6 2.7 6.1 23.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.6 GBG63140.1 - 4.7 6.7 7.8 8.6 5.9 7.8 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain BUD22 PF09073.10 GBG63140.1 - 5.2 6.3 24.3 7.1 5.9 24.3 1.1 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 GBG63140.1 - 5.4 6.3 13.5 8.6 5.7 13.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 GBG63140.1 - 7.4 5.9 27.3 11 5.4 27.3 1.1 1 0 0 1 1 1 0 SDA1 PEPCK_ATP PF01293.20 GBG63141.1 - 1.7e-210 699.6 0.0 1.9e-210 699.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase RC-P840_PscD PF10657.9 GBG63141.1 - 0.06 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD AAA_24 PF13479.6 GBG63141.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Integrase_H2C2 PF17921.1 GBG63142.1 - 2.2e-15 56.5 2.7 6.3e-15 55.0 0.3 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG63142.1 - 2.1e-13 50.2 0.0 4.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63142.1 - 6.8e-12 45.6 0.0 1.5e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63142.1 - 1.4e-07 31.7 0.0 3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain FGGY_C PF02782.16 GBG63143.1 - 1.9e-64 217.0 0.2 5.2e-64 215.6 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GBG63143.1 - 1.2e-53 182.2 0.4 1.6e-35 122.9 0.1 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain SelK_SelG PF10961.8 GBG63143.1 - 0.48 11.1 5.3 3.9 8.1 2.5 2.6 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Ribosomal_60s PF00428.19 GBG63143.1 - 4.2 8.0 7.2 12 6.6 7.2 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Serinc PF03348.15 GBG63144.1 - 0.00015 20.9 5.2 0.00015 20.9 5.2 1.8 2 0 0 2 2 2 1 Serine incorporator (Serinc) LAP1C PF05609.12 GBG63144.1 - 0.00077 18.7 4.4 0.00077 18.7 4.4 2.0 2 0 0 2 2 2 1 Lamina-associated polypeptide 1C (LAP1C) DUF2207 PF09972.9 GBG63144.1 - 0.001 17.9 8.8 0.0013 17.6 8.8 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Apt1 PF10351.9 GBG63144.1 - 0.002 17.1 7.0 0.002 17.1 7.0 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain SARAF PF06682.12 GBG63144.1 - 0.0023 17.6 2.6 0.0023 17.6 2.6 2.3 1 1 1 2 2 1 1 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 GBG63144.1 - 0.0033 16.3 15.8 0.0043 15.9 15.8 1.3 1 0 0 1 1 1 1 Presenilin MFS_1 PF07690.16 GBG63144.1 - 0.0046 15.9 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily LTV PF04180.14 GBG63144.1 - 0.0047 16.7 22.7 0.0054 16.5 22.7 1.2 1 0 0 1 1 1 1 Low temperature viability protein Atg14 PF10186.9 GBG63144.1 - 0.0073 15.4 9.6 0.0074 15.4 9.6 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Connexin PF00029.19 GBG63144.1 - 0.0082 15.9 17.2 0.0082 15.9 17.2 2.2 2 0 0 2 2 2 1 Connexin Neur_chan_memb PF02932.16 GBG63144.1 - 0.0097 16.0 6.2 0.018 15.1 6.2 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region HCO3_cotransp PF00955.21 GBG63144.1 - 0.011 14.6 1.2 0.016 14.1 1.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family AA_permease_2 PF13520.6 GBG63144.1 - 0.012 14.5 0.7 0.016 14.0 0.7 1.1 1 0 0 1 1 1 0 Amino acid permease SLC12 PF03522.15 GBG63144.1 - 0.038 13.0 18.8 0.052 12.6 18.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DcuA_DcuB PF03605.14 GBG63144.1 - 0.043 12.7 8.6 0.013 14.4 5.8 1.5 1 1 1 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Pkinase_fungal PF17667.1 GBG63144.1 - 0.068 11.9 5.5 0.091 11.5 5.5 1.1 1 0 0 1 1 1 0 Fungal protein kinase Otopetrin PF03189.13 GBG63144.1 - 0.099 11.4 2.9 0.14 10.9 2.9 1.3 1 0 0 1 1 1 0 Otopetrin SID-1_RNA_chan PF13965.6 GBG63144.1 - 0.1 11.0 4.6 0.14 10.5 4.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 GBG63144.1 - 0.13 11.2 4.4 0.19 10.6 4.4 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2370 PF10176.9 GBG63144.1 - 0.18 11.5 2.9 0.32 10.6 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) ASC PF00858.24 GBG63144.1 - 0.18 10.7 6.9 0.27 10.2 6.9 1.3 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel SDA1 PF05285.12 GBG63144.1 - 0.22 10.9 51.7 0.32 10.4 51.7 1.2 1 0 0 1 1 1 0 SDA1 EMC3_TMCO1 PF01956.16 GBG63144.1 - 0.37 10.5 15.7 0.61 9.8 15.7 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PTR2 PF00854.21 GBG63144.1 - 0.61 8.8 8.3 0.83 8.4 8.3 1.1 1 0 0 1 1 1 0 POT family Glypican PF01153.19 GBG63144.1 - 0.7 8.7 15.0 0.77 8.5 14.6 1.3 1 1 0 1 1 1 0 Glypican CPP1-like PF11833.8 GBG63144.1 - 0.71 9.5 3.7 1.1 8.9 3.7 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like CCSAP PF15748.5 GBG63144.1 - 0.85 9.7 34.8 1.3 9.1 34.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4471 PF14740.6 GBG63144.1 - 1.4 8.0 15.3 0.031 13.5 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Kei1 PF08552.11 GBG63144.1 - 1.8 8.4 7.6 0.043 13.7 1.4 1.4 2 0 0 2 2 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4366 PF14283.6 GBG63144.1 - 9.6 6.2 22.7 0.12 12.4 9.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) RT_RNaseH_2 PF17919.1 GBG63145.1 - 1.6e-25 89.0 0.0 4.8e-25 87.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63145.1 - 2.3e-25 88.9 0.3 1.5e-24 86.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63145.1 - 1.2e-14 54.4 0.1 2.4e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNN_linker PF09050.10 GBG63146.1 - 0.99 9.2 2.8 23 4.9 0.8 2.6 2 0 0 2 2 2 0 Stannin unstructured linker Utp14 PF04615.13 GBG63146.1 - 3.2 6.2 23.5 3.7 6.0 23.5 1.0 1 0 0 1 1 1 0 Utp14 protein RVT_1 PF00078.27 GBG63148.1 - 4.4e-25 88.5 0.1 7.9e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1896 PF08989.10 GBG63149.1 - 0.035 14.2 0.1 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) RT_RNaseH_2 PF17919.1 GBG63150.1 - 3.5e-19 68.7 0.0 6.8e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63150.1 - 8e-19 67.9 0.0 1.5e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63150.1 - 9.5e-14 51.3 0.1 2.8e-13 49.7 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG63150.1 - 5.3e-05 23.7 0.0 0.00013 22.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63150.1 - 0.002 18.7 0.0 0.005 17.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG63150.1 - 0.073 13.4 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG63150.1 - 0.08 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger zf-RING_2 PF13639.6 GBG63151.1 - 1.1e-09 38.4 6.8 1.1e-09 38.4 6.8 1.8 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 GBG63151.1 - 3.6e-08 33.6 6.8 7e-08 32.6 6.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GBG63151.1 - 1.2e-07 31.4 1.1 2.9e-07 30.1 1.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 GBG63151.1 - 2.9e-07 30.3 4.3 2.9e-07 30.3 4.3 2.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GBG63151.1 - 3.7e-07 29.9 8.5 3.7e-07 29.9 8.5 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG63151.1 - 8.4e-06 25.6 5.7 1.5e-05 24.8 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG63151.1 - 2.1e-05 24.3 6.0 4.6e-05 23.2 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG63151.1 - 0.00012 21.9 5.0 0.00023 21.0 5.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GBG63151.1 - 0.00015 21.7 1.5 0.00015 21.7 1.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GBG63151.1 - 0.0006 19.8 2.5 0.0015 18.6 2.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 GBG63151.1 - 0.0014 16.6 1.7 0.039 11.8 1.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2921) FANCL_C PF11793.8 GBG63151.1 - 0.022 14.9 4.5 0.072 13.3 4.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.14 GBG63151.1 - 0.024 14.3 1.2 0.024 14.3 1.2 2.8 4 0 0 4 4 4 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 GBG63151.1 - 0.074 12.7 10.2 0.034 13.8 7.1 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GBG63151.1 - 0.3 10.9 5.0 0.55 10.1 5.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 GBG63151.1 - 0.66 10.2 6.3 1.5 9.0 6.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 GBG63151.1 - 2.7 8.4 5.1 6.7 7.1 5.1 1.7 1 0 0 1 1 1 0 RING-like domain SecY PF00344.20 GBG63152.1 - 1.8e-75 254.1 11.8 2.3e-75 253.7 11.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 GBG63152.1 - 5.1e-19 67.8 0.2 1.8e-18 66.1 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p G6PD_C PF02781.16 GBG63153.1 - 1.6e-111 372.1 0.0 2.1e-111 371.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GBG63153.1 - 6e-58 196.4 0.0 9.3e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Pkinase PF00069.25 GBG63154.1 - 2e-44 152.0 0.0 2.6e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63154.1 - 1e-19 70.8 0.0 1.5e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF962 PF06127.11 GBG63155.1 - 8.3e-30 102.7 0.0 1.9e-29 101.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Amidase PF01425.21 GBG63157.1 - 2.8e-56 191.4 1.1 1.9e-48 165.5 0.8 2.2 2 0 0 2 2 2 2 Amidase TPR_1 PF00515.28 GBG63157.1 - 2e-16 59.0 6.6 1.4e-06 27.8 1.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG63157.1 - 7.3e-15 53.8 6.8 2.6e-06 27.1 1.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG63157.1 - 1.8e-08 33.9 4.7 7.7e-07 28.7 2.1 3.1 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.6 GBG63157.1 - 2.5e-08 33.9 0.1 0.00043 20.4 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG63157.1 - 3.5e-08 33.0 2.9 0.0011 19.0 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG63157.1 - 7e-07 29.2 3.0 0.0003 20.9 1.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG63157.1 - 9.3e-07 29.4 4.4 0.00024 21.7 0.3 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG63157.1 - 1.9e-05 24.3 0.1 0.042 13.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG63157.1 - 2.8e-05 24.6 1.5 0.013 16.2 0.1 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG63157.1 - 0.0019 18.6 2.5 0.006 17.1 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG63157.1 - 0.014 15.7 4.8 0.038 14.3 1.7 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG63157.1 - 0.15 12.7 1.9 8 7.3 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 GBG63158.1 - 6.2e-27 93.6 0.0 1.1e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63158.1 - 1.2e-23 83.3 0.0 2.3e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG63158.1 - 0.23 9.7 6.8 0.3 9.3 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG63158.1 - 0.96 7.6 7.3 1.1 7.4 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_4 PF13837.6 GBG63159.1 - 4.1e-06 27.1 0.1 4.1e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG63159.1 - 1.7e-05 24.7 3.4 6e-05 22.9 3.4 2.0 1 0 0 1 1 1 1 Zinc knuckle Myb_DNA-bind_5 PF13873.6 GBG63159.1 - 0.0042 17.1 0.3 0.014 15.5 0.3 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CN_hydrolase PF00795.22 GBG63160.1 - 8.7e-23 81.0 0.0 2.1e-21 76.4 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase RT_RNaseH PF17917.1 GBG63161.1 - 7.2e-25 87.3 0.0 2e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63161.1 - 8.7e-15 55.0 0.1 3.6e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG63161.1 - 1e-14 54.4 0.0 2.8e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63161.1 - 7.6e-08 32.3 0.0 1.9e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG63161.1 - 1.8e-07 31.3 0.3 5.1e-07 29.9 0.3 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG63161.1 - 2.4e-05 24.4 0.1 5.6e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG63161.1 - 0.0001 22.2 0.1 0.00034 20.6 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle DUF3446 PF11928.8 GBG63161.1 - 6.8 7.1 9.0 4.8 7.5 5.6 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain DDE_Tnp_4 PF13359.6 GBG63163.1 - 5.2e-20 71.7 0.0 7.4e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63163.1 - 4.6e-07 29.6 0.0 7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG63163.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Apolipoprotein PF01442.18 GBG63164.1 - 5.3e-10 39.5 29.5 5e-07 29.8 15.1 2.3 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 GBG63164.1 - 0.0011 18.9 5.0 0.0011 18.9 5.0 6.1 4 2 2 6 6 6 3 Late embryogenesis abundant protein DUF883 PF05957.13 GBG63164.1 - 0.024 15.2 26.1 0.18 12.4 0.8 5.3 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GBG63164.1 - 0.033 14.7 47.0 0.17 12.4 3.4 5.3 2 2 2 4 4 4 0 YtxH-like protein WBS_methylT PF12589.8 GBG63164.1 - 0.28 12.0 0.2 0.28 12.0 0.2 3.9 3 1 0 3 3 3 0 Methyltransferase involved in Williams-Beuren syndrome Phasin PF05597.11 GBG63164.1 - 0.4 10.7 27.0 0.24 11.4 5.2 4.2 2 2 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoLp-III PF07464.11 GBG63164.1 - 1.1 9.3 29.6 0.18 11.9 13.5 3.6 2 2 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Gp-FAR-1 PF05823.12 GBG63164.1 - 4 7.8 18.6 3 8.2 7.1 3.8 2 2 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Myb_DNA-bind_4 PF13837.6 GBG63165.1 - 8.9e-05 22.8 3.1 0.00015 22.0 3.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG63166.1 - 1e-23 83.2 0.0 1.8e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63166.1 - 6.9e-22 77.7 0.0 1.3e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63166.1 - 4.5e-15 55.5 0.3 9.7e-15 54.4 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63166.1 - 1.7e-11 44.1 0.1 3e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Longin PF13774.6 GBG63166.1 - 0.02 14.9 0.2 0.55 10.3 0.1 2.4 2 0 0 2 2 2 0 Regulated-SNARE-like domain zf-H2C2 PF09337.10 GBG63166.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Hexapep PF00132.24 GBG63167.1 - 1.6e-18 65.7 17.7 7.6e-07 28.6 1.3 6.0 5 1 1 6 6 6 3 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.6 GBG63167.1 - 4.3e-17 62.3 0.0 7.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep_2 PF14602.6 GBG63167.1 - 0.018 14.8 6.6 0.81 9.5 0.1 3.9 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Myb_DNA-bind_4 PF13837.6 GBG63169.1 - 1.7e-07 31.5 2.2 1.7e-07 31.5 2.2 2.5 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Tubulin PF00091.25 GBG63169.1 - 0.0082 16.4 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain MADF_DNA_bdg PF10545.9 GBG63169.1 - 0.1 12.9 0.4 0.29 11.5 0.4 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Coatomer_g_Cpla PF16381.5 GBG63170.1 - 0.047 13.8 0.3 0.097 12.8 0.3 1.5 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform Activator-TraM PF11657.8 GBG63170.1 - 0.34 10.7 2.7 0.49 10.2 2.7 1.2 1 0 0 1 1 1 0 Transcriptional activator TraM Amidohydro_1 PF01979.20 GBG63172.1 - 0.016 14.5 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Amidohydrolase family RVT_1 PF00078.27 GBG63173.1 - 1.7e-32 112.8 0.0 3e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Amidohydro_1 PF01979.20 GBG63173.1 - 9.8e-21 74.4 9.4 7.9e-13 48.4 0.0 3.4 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_3 PF07969.11 GBG63173.1 - 2.5e-10 40.4 0.0 7.4e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family RT_RNaseH_2 PF17919.1 GBG63173.1 - 0.013 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Haemagg_act PF05860.13 GBG63173.1 - 0.044 13.7 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 haemagglutination activity domain tRNA-synt_1_2 PF13603.6 GBG63173.1 - 0.058 12.9 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 DUF659 PF04937.15 GBG63174.1 - 1.8e-29 102.5 0.2 2.8e-29 101.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) FUSC PF04632.12 GBG63174.1 - 1.2 7.6 5.3 2.3 6.6 5.3 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family WRKY PF03106.15 GBG63176.1 - 2.1e-45 152.8 20.8 8.4e-25 86.8 6.1 2.3 2 0 0 2 2 2 2 WRKY DNA -binding domain zf_CopZ PF18423.1 GBG63176.1 - 0.21 11.6 2.2 4.7 7.2 0.2 2.5 2 0 0 2 2 2 0 Zinc binding domain zf-GRF PF06839.12 GBG63176.1 - 1.1 9.4 7.2 5.6 7.1 0.7 2.6 2 0 0 2 2 2 0 GRF zinc finger RVT_1 PF00078.27 GBG63178.1 - 1e-27 97.1 0.1 1.5e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63178.1 - 5.8e-24 84.0 0.0 1.2e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63178.1 - 3.5e-15 56.2 0.0 6.7e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG63178.1 - 2e-09 37.9 0.0 4.6e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63178.1 - 4.7e-09 36.8 0.0 1.4e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG63178.1 - 3e-07 30.2 0.0 5.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63178.1 - 6e-07 29.3 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG63179.1 - 0.05 13.9 3.4 0.11 12.8 0.1 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein Lactamase_B_2 PF12706.7 GBG63180.1 - 1.2e-18 67.3 0.1 1.7e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GBG63180.1 - 1.3e-08 35.1 0.2 1.7e-08 34.7 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 GBG63180.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Glyco_hydro_31 PF01055.26 GBG63182.1 - 6.5e-48 164.0 0.0 3.8e-47 161.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.18 GBG63182.1 - 0.021 13.8 0.2 0.062 12.2 0.2 1.6 1 1 0 1 1 1 0 Melibiase TPR_2 PF07719.17 GBG63184.1 - 0.00023 21.0 3.8 0.092 12.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG63184.1 - 0.00097 18.9 4.4 0.12 12.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG63184.1 - 0.0017 18.6 2.4 2.8 8.5 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG63184.1 - 0.0087 16.8 0.2 4.5 8.3 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG63184.1 - 0.009 16.5 3.3 0.35 11.4 0.7 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG63184.1 - 1.3 8.8 3.9 27 4.5 0.9 2.9 2 1 0 2 2 2 0 TPR repeat Protocadherin PF08374.11 GBG63184.1 - 2 8.3 5.9 3.8 7.4 5.9 1.4 1 0 0 1 1 1 0 Protocadherin BRF1 PF07741.13 GBG63184.1 - 4 7.8 16.1 10 6.5 0.9 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain TPR_16 PF13432.6 GBG63184.1 - 5.2 7.8 12.1 2 9.1 1.9 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG63185.1 - 0.00039 20.3 3.8 0.11 12.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG63185.1 - 0.0016 18.2 4.4 0.15 12.0 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG63185.1 - 0.0027 17.9 2.4 3.3 8.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG63185.1 - 0.013 16.0 3.3 0.42 11.2 0.7 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG63185.1 - 0.014 16.1 0.2 5.4 8.1 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GBG63185.1 - 1.6 8.5 3.7 31 4.3 0.8 2.8 2 1 0 2 2 2 0 TPR repeat Protocadherin PF08374.11 GBG63185.1 - 3.3 7.7 6.2 6 6.8 6.2 1.4 1 0 0 1 1 1 0 Protocadherin BRF1 PF07741.13 GBG63185.1 - 4.9 7.5 15.8 12 6.3 0.8 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain TPR_16 PF13432.6 GBG63185.1 - 6.8 7.4 11.9 2.1 9.0 1.8 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF659 PF04937.15 GBG63186.1 - 5.8e-34 117.1 0.0 9.9e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63186.1 - 9.7e-06 25.3 0.1 2.1e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Defensin_beta_2 PF13841.6 GBG63186.1 - 0.29 11.7 2.9 0.78 10.3 2.9 1.7 1 0 0 1 1 1 0 Beta defensin RVT_1 PF00078.27 GBG63187.1 - 1.2e-27 96.9 0.0 1.9e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63187.1 - 1.7e-17 63.6 0.0 5.1e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63187.1 - 3.3e-11 43.1 0.0 2.7e-10 40.2 0.0 2.5 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG63187.1 - 2.3e-07 31.3 0.0 4.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63187.1 - 2.5e-06 28.0 0.0 5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63187.1 - 7.9e-06 25.7 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63187.1 - 0.00031 20.5 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Connexin PF00029.19 GBG63190.1 - 0.0015 18.3 0.2 0.0022 17.8 0.2 1.3 1 0 0 1 1 1 1 Connexin Presenilin PF01080.17 GBG63190.1 - 0.03 13.1 2.5 0.032 13.0 2.5 1.2 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 GBG63190.1 - 0.047 13.6 8.5 0.066 13.1 8.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain V_ATPase_I PF01496.19 GBG63190.1 - 0.053 11.4 1.2 0.055 11.4 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 GBG63190.1 - 0.12 12.2 9.9 0.13 12.0 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SARAF PF06682.12 GBG63190.1 - 0.13 11.9 8.3 0.26 10.9 8.1 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Zip PF02535.22 GBG63190.1 - 0.14 11.4 1.0 0.14 11.3 1.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_polI_A34 PF08208.11 GBG63190.1 - 0.28 11.3 20.0 0.41 10.7 20.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 eIF-3_zeta PF05091.12 GBG63190.1 - 0.5 9.3 5.5 0.51 9.2 5.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sec62 PF03839.16 GBG63190.1 - 0.67 9.4 9.9 16 4.9 0.0 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 NPR3 PF03666.13 GBG63190.1 - 4.1 6.1 8.0 4.3 6.0 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2967 PF11179.8 GBG63190.1 - 7.8 4.5 12.5 8.8 4.3 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF2201_N PF13203.6 GBG63191.1 - 2.4 7.7 5.8 1.5 8.4 3.4 1.8 1 1 1 2 2 2 0 Putative metallopeptidase domain ZF-HD_dimer PF04770.12 GBG63194.1 - 5e-14 52.4 5.5 2.1e-13 50.4 2.1 3.4 3 0 0 3 3 3 1 ZF-HD protein dimerisation region DUF4379 PF14311.6 GBG63194.1 - 1.4e-06 28.6 17.1 0.037 14.4 0.6 3.9 3 0 0 3 3 3 3 Probable Zinc-ribbon domain zf-ribbon_3 PF13248.6 GBG63194.1 - 0.00018 20.8 7.6 1.6 8.3 0.1 4.2 3 0 0 3 3 3 3 zinc-ribbon domain MAP70 PF07058.11 GBG63194.1 - 0.12 11.1 4.4 0.17 10.6 4.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 RR_TM4-6 PF06459.12 GBG63194.1 - 0.45 10.3 13.2 0.77 9.5 13.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 GBG63194.1 - 1.6 8.6 3.8 3 7.7 3.8 1.5 1 0 0 1 1 1 0 N-glycosylation protein ALMT PF11744.8 GBG63194.1 - 1.7 7.4 14.1 2.6 6.8 14.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter AUX_IAA PF02309.16 GBG63194.1 - 2.9 7.7 7.1 4.8 7.0 7.1 1.3 1 0 0 1 1 1 0 AUX/IAA family VIR_N PF15912.5 GBG63194.1 - 3.3 7.3 12.1 5.9 6.4 12.1 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal TFIIA PF03153.13 GBG63194.1 - 3.3 7.6 39.0 0.85 9.5 33.6 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 GBG63194.1 - 3.3 7.7 14.5 1.6 8.7 11.7 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Endostatin PF06482.11 GBG63194.1 - 5.9 6.3 24.5 0.4 10.1 19.0 1.7 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin CPSF100_C PF13299.6 GBG63194.1 - 7.6 6.7 8.4 15 5.7 8.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zn-ribbon_8 PF09723.10 GBG63194.1 - 8.3 6.6 22.5 7.8 6.7 0.2 5.5 4 2 0 4 4 4 0 Zinc ribbon domain HCO3_cotransp PF00955.21 GBG63194.1 - 9.2 5.0 6.8 13 4.4 6.8 1.1 1 0 0 1 1 1 0 HCO3- transporter family RT_RNaseH_2 PF17919.1 GBG63196.1 - 2.1e-23 82.2 0.0 4.4e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MatE PF01554.18 GBG63196.1 - 5.6e-18 65.1 34.1 2.7e-12 46.6 0.0 5.1 5 0 0 5 5 5 4 MatE RT_RNaseH PF17917.1 GBG63196.1 - 3.6e-14 52.9 0.0 8.3e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Polysacc_synt_C PF14667.6 GBG63196.1 - 2.8e-06 27.4 10.5 2.8e-06 27.4 10.5 2.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain Retrotrans_gag PF03732.17 GBG63196.1 - 0.0018 18.5 0.3 0.031 14.5 0.1 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein Ribonuc_2-5A PF06479.12 GBG63196.1 - 0.12 12.5 0.2 0.26 11.5 0.2 1.5 1 0 0 1 1 1 0 Ribonuclease 2-5A LRR_4 PF12799.7 GBG63197.1 - 2.8e-35 119.8 30.5 9.5e-08 32.2 2.1 7.4 6 1 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG63197.1 - 6.1e-23 80.3 36.4 9.8e-07 28.4 1.2 6.9 3 2 6 9 9 9 7 Leucine rich repeat LRR_9 PF14580.6 GBG63197.1 - 7.4e-17 61.4 11.8 1.8e-06 27.5 0.1 3.9 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 GBG63197.1 - 5.5e-05 23.2 27.2 15 6.6 0.0 9.8 9 3 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 GBG63197.1 - 0.0015 18.4 30.9 0.72 10.1 0.2 8.9 10 0 0 10 10 10 3 Leucine Rich repeat CENP-R PF06729.12 GBG63197.1 - 2.1 8.3 4.4 2.2 8.2 0.4 2.7 2 1 1 3 3 3 0 Kinetochore component, CENP-R SLBP_RNA_bind PF15247.6 GBG63198.1 - 6.1 7.0 16.1 5.9 7.1 3.2 3.1 3 0 0 3 3 3 0 Histone RNA hairpin-binding protein RNA-binding domain Rrn6 PF10214.9 GBG63198.1 - 8.1 4.8 11.2 6.1 5.2 4.7 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor RVT_1 PF00078.27 GBG63199.1 - 3.6e-10 39.8 0.0 6.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG63199.1 - 1.7e-08 34.9 0.0 4.5e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63199.1 - 8.9e-06 26.3 0.4 3.6e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG63199.1 - 0.0026 17.6 0.2 0.0047 16.7 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG63199.1 - 0.018 15.4 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG63199.1 - 0.03 14.4 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain SICA_C PF12879.7 GBG63199.1 - 0.073 13.1 0.5 0.2 11.7 0.5 1.8 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain SlyX PF04102.12 GBG63200.1 - 1.1 9.9 8.3 0.16 12.6 1.5 2.6 2 0 0 2 2 2 0 SlyX RT_RNaseH_2 PF17919.1 GBG63203.1 - 9.2e-32 109.1 0.0 1.6e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63203.1 - 9.5e-31 106.2 0.1 3.1e-30 104.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63203.1 - 1.5e-06 27.9 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG63206.1 - 9e-21 74.4 0.1 1.3e-20 73.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG63207.1 - 1.7e-14 53.9 0.0 3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG63208.1 - 2.1e-31 109.2 0.1 3.7e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63208.1 - 1.8e-12 47.5 0.0 5.1e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Peptidase_C36 PF05415.11 GBG63208.1 - 0.025 14.8 0.0 0.078 13.2 0.0 1.8 2 0 0 2 2 2 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase ThiD2 PF17792.1 GBG63208.1 - 0.071 13.6 0.5 0.9 10.0 0.0 2.8 3 0 0 3 3 3 0 ThiD2 family rve_3 PF13683.6 GBG63208.1 - 0.11 12.3 0.0 0.41 10.4 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain HHH_3 PF12836.7 GBG63208.1 - 0.17 12.2 0.0 1.2 9.5 0.1 2.4 3 0 0 3 3 3 0 Helix-hairpin-helix motif DUF1474 PF07342.11 GBG63208.1 - 0.18 12.4 0.1 0.46 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) EAP30 PF04157.16 GBG63208.1 - 0.2 10.9 1.0 0.41 9.9 1.0 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family Suv3_C_1 PF18147.1 GBG63209.1 - 3.9e-13 49.0 0.0 7.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 GBG63209.1 - 1.4e-12 48.0 0.0 2.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Kinesin PF00225.23 GBG63209.1 - 0.072 12.0 0.0 0.096 11.6 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain RT_RNaseH PF17917.1 GBG63210.1 - 1.4e-21 76.7 0.0 3.1e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63210.1 - 2.5e-21 75.6 0.0 5.5e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63210.1 - 5.8e-20 71.1 0.1 1.3e-19 70.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63210.1 - 8e-20 71.3 0.0 2.2e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63210.1 - 4.4e-09 36.5 0.0 1.8e-08 34.6 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG63210.1 - 4.6e-08 33.6 0.0 1.5e-07 32.0 0.0 1.9 2 0 0 2 2 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63210.1 - 6e-08 32.5 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG63210.1 - 5.3e-06 26.9 0.0 2.1e-05 25.0 0.0 2.0 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG63210.1 - 0.0081 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG63210.1 - 0.024 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG63210.1 - 0.031 14.5 0.1 0.12 12.6 0.1 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG63210.1 - 0.096 12.9 0.0 0.32 11.3 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger AT_hook PF02178.19 GBG63211.1 - 0.13 12.2 6.3 0.6 10.2 6.3 2.3 1 0 0 1 1 1 0 AT hook motif Spermine_synth PF01564.17 GBG63212.1 - 1.6e-65 220.1 0.0 3.8e-65 218.8 0.0 1.6 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 GBG63212.1 - 1.6e-24 85.5 0.1 2.5e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GBG63212.1 - 6.5e-06 26.8 0.2 1.9e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG63212.1 - 0.025 15.2 0.0 0.13 12.9 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GBG63212.1 - 0.098 13.4 0.1 1.1 10.1 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Spermine_synth PF01564.17 GBG63215.1 - 4.5e-14 52.3 0.0 6.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Peptidase_M22 PF00814.25 GBG63216.1 - 2e-86 290.1 0.0 2.3e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 GBG63216.1 - 0.13 11.9 0.2 0.35 10.5 0.0 1.8 2 1 0 2 2 2 0 Carbamoyltransferase N-terminus C2 PF00168.30 GBG63217.1 - 5.2e-17 62.0 0.0 7.8e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF4795 PF16043.5 GBG63219.1 - 0.00092 18.9 2.6 0.0011 18.7 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) ZapB PF06005.12 GBG63219.1 - 0.032 14.6 7.2 0.2 12.1 0.4 2.1 1 1 1 2 2 2 0 Cell division protein ZapB DASH_Dam1 PF08653.10 GBG63219.1 - 0.04 13.7 1.2 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 SHE3 PF17078.5 GBG63219.1 - 0.041 13.6 6.1 0.047 13.4 6.1 1.0 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Nab1 PF04902.12 GBG63219.1 - 0.12 12.7 3.6 0.079 13.4 1.5 1.7 1 1 1 2 2 2 0 Conserved region in Nab1 dCache_2 PF08269.11 GBG63219.1 - 0.79 8.8 3.7 0.89 8.7 3.7 1.0 1 0 0 1 1 1 0 Cache domain NPV_P10 PF05531.12 GBG63219.1 - 0.82 10.2 5.1 1.6 9.3 2.1 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 GBG63219.1 - 0.93 10.2 6.1 2.6 8.7 6.1 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Sel1 PF08238.12 GBG63221.1 - 5.5e-273 875.2 134.7 1.7e-12 47.6 1.3 33.5 33 0 0 33 33 33 31 Sel1 repeat TPR_16 PF13432.6 GBG63221.1 - 3.6e-08 33.9 83.4 2.2 9.0 1.3 18.8 12 5 10 22 22 22 8 Tetratricopeptide repeat TPR_6 PF13174.6 GBG63221.1 - 2.8e-05 24.4 40.7 10 7.0 0.1 16.6 20 1 1 21 21 21 3 Tetratricopeptide repeat TPR_17 PF13431.6 GBG63221.1 - 0.00025 21.2 19.5 2.9 8.5 0.0 12.6 14 2 1 15 15 15 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG63221.1 - 0.0012 18.5 0.6 0.0012 18.5 0.6 18.6 21 1 0 21 21 21 4 TPR repeat IMPa_N_2 PF18650.1 GBG63221.1 - 0.0066 15.7 0.9 0.23 10.7 0.1 3.3 3 0 0 3 3 3 1 Immunomodulating metalloprotease N-terminal domain TPR_7 PF13176.6 GBG63221.1 - 0.091 12.8 49.0 0.55 10.4 0.0 15.9 17 2 2 19 19 19 0 Tetratricopeptide repeat pP_pnuc_1 PF18165.1 GBG63221.1 - 7.1 6.5 5.2 70 3.3 0.0 4.8 5 2 1 6 6 6 0 Predicted pPIWI-associating nuclease EPOP PF15223.6 GBG63223.1 - 0.0089 15.4 5.6 0.012 15.0 5.6 1.2 1 0 0 1 1 1 1 Elongin BC and Polycomb repressive complex 2-associated protein Gp_dh_C PF02800.20 GBG63224.1 - 6e-70 233.9 0.0 7.9e-70 233.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG63224.1 - 6.5e-38 129.1 0.0 1.9e-37 127.6 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG63224.1 - 0.0039 17.3 0.2 0.016 15.4 0.0 2.2 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Radical_SAM PF04055.21 GBG63224.1 - 0.028 14.8 0.0 0.43 10.9 0.0 2.1 2 0 0 2 2 2 0 Radical SAM superfamily BAMBI PF06211.12 GBG63226.1 - 0.014 15.6 0.1 0.046 14.0 0.1 1.8 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain zf-C2H2_6 PF13912.6 GBG63226.1 - 0.06 13.4 2.3 0.18 11.8 2.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Myb_DNA-bind_4 PF13837.6 GBG63227.1 - 7.7e-10 39.0 0.7 7.7e-10 39.0 0.7 2.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG63227.1 - 0.005 17.1 2.6 0.011 16.1 0.1 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG63228.1 - 9.2e-29 100.1 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63228.1 - 5.9e-15 55.4 0.0 9.5e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG63228.1 - 0.00077 19.2 0.1 0.65 9.6 0.3 2.4 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG63228.1 - 0.056 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain DUF659 PF04937.15 GBG63229.1 - 7e-27 94.2 0.0 1.5e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG63229.1 - 9.2e-08 31.8 2.9 2.4e-07 30.5 2.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG63229.1 - 0.017 14.8 1.5 0.049 13.3 1.5 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Prok-RING_1 PF14446.6 GBG63229.1 - 1.1 9.3 3.5 0.8 9.7 0.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PPL5 PF18168.1 GBG63229.1 - 5.3 6.3 11.8 1.7 7.8 8.8 1.7 1 1 0 1 1 1 0 Prim-pol family 5 DUF659 PF04937.15 GBG63230.1 - 1.8e-14 53.9 0.0 4.2e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Trans_reg_C PF00486.28 GBG63230.1 - 0.19 11.8 1.2 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal FAP206 PF12018.8 GBG63230.1 - 0.5 9.8 9.1 1.2 8.6 9.1 1.6 1 0 0 1 1 1 0 Domain of unknown function UPF0242 PF06785.11 GBG63230.1 - 2.9 8.0 18.3 8.2 6.5 18.3 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF212 PF02681.14 GBG63232.1 - 7.9e-43 145.6 0.4 2.1e-36 124.8 0.0 2.2 2 0 0 2 2 2 2 Divergent PAP2 family RT_RNaseH_2 PF17919.1 GBG63233.1 - 1.8e-23 82.5 0.1 2.2e-15 56.5 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63233.1 - 1.8e-21 76.4 0.0 5.3e-21 74.9 0.0 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63233.1 - 2.9e-19 69.5 0.0 5e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG63233.1 - 2.8e-08 33.7 0.0 7.8e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63233.1 - 0.00092 19.4 0.2 0.0041 17.3 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain zf-CCHC PF00098.23 GBG63233.1 - 0.0062 16.6 2.7 0.022 14.8 2.7 2.0 1 0 0 1 1 1 1 Zinc knuckle ESM4 PF15952.5 GBG63233.1 - 0.9 10.0 8.3 2 8.8 8.3 1.6 1 0 0 1 1 1 0 Enhancer of split M4 family ANATO PF01821.18 GBG63233.1 - 1.7 9.5 4.0 5.3 8.0 4.0 1.9 1 0 0 1 1 1 0 Anaphylotoxin-like domain RVT_1 PF00078.27 GBG63234.1 - 1.9e-31 109.3 0.0 3.4e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63234.1 - 2.6e-30 104.4 0.0 5.9e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63234.1 - 7.7e-30 103.3 0.1 1.8e-29 102.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63234.1 - 1.5e-06 28.2 0.0 4.1e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG63234.1 - 6.1e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63234.1 - 0.0014 19.2 0.0 0.0032 18.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63234.1 - 0.017 15.7 0.0 0.057 14.0 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG63234.1 - 0.14 11.9 0.1 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 GBG63235.1 - 2e-19 69.5 0.1 3.2e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63235.1 - 1.1e-06 28.9 0.0 3.3e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG63235.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG63237.1 - 9.2e-25 87.4 0.1 1.5e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG63237.1 - 2.3e-15 56.4 0.3 4.4e-15 55.5 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG63237.1 - 4e-12 46.4 0.9 7.8e-12 45.4 0.9 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63237.1 - 6.4e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63237.1 - 0.013 15.7 0.0 0.047 13.9 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 GBG63237.1 - 0.025 14.8 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG63238.1 - 5.6e-31 106.5 0.0 9.4e-16 57.7 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63238.1 - 2.9e-30 104.6 0.0 5.8e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63238.1 - 1.6e-09 37.6 0.0 2.8e-08 33.5 0.0 2.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG63239.1 - 0.0011 19.2 1.2 0.007 16.6 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG63239.1 - 0.0075 16.0 0.5 0.0075 16.0 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) SlyX PF04102.12 GBG63239.1 - 0.022 15.3 3.2 0.022 15.3 3.2 2.7 3 0 0 3 3 3 0 SlyX DUF16 PF01519.16 GBG63239.1 - 1.9 9.0 4.8 0.87 10.1 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 RT_RNaseH PF17917.1 GBG63240.1 - 1.6e-22 79.8 0.0 3.3e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63240.1 - 1.8e-22 79.3 0.0 3.3e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63240.1 - 3.8e-12 46.1 0.0 1.1e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG63240.1 - 0.00082 20.0 0.0 0.0019 18.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG63240.1 - 0.0023 18.2 0.0 0.0068 16.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG63240.1 - 0.0037 17.8 0.1 0.0077 16.8 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG63240.1 - 0.024 14.9 0.2 0.074 13.3 0.2 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG63240.1 - 0.069 13.0 0.5 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.27 GBG63241.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG63241.1 - 0.15 12.3 1.3 0.45 10.8 0.1 2.4 2 1 0 2 2 2 0 Retrotransposon gag protein RVP_2 PF08284.11 GBG63241.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GBG63241.1 - 0.72 9.7 5.8 0.061 13.2 1.0 1.8 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG63242.1 - 0.0055 16.2 0.1 0.01 15.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG63242.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG63243.1 - 0.029 14.5 1.8 0.074 13.2 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG63243.1 - 5.6 6.9 8.3 0.61 10.0 3.2 2.0 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH PF17917.1 GBG63244.1 - 1.5e-29 102.4 0.5 6.6e-29 100.3 0.0 2.3 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63244.1 - 1.6e-29 101.9 0.0 5.9e-29 100.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63244.1 - 1.3e-11 44.4 0.1 2.6e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG63244.1 - 0.051 13.2 0.0 0.051 13.2 0.0 3.1 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Rhamno_transf PF11316.8 GBG63244.1 - 0.088 12.2 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Putative rhamnosyl transferase TssO PF17561.2 GBG63244.1 - 0.58 10.2 3.3 5.5 7.1 3.3 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF3138 PF11336.8 GBG63244.1 - 0.8 8.2 2.7 1.3 7.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BAF1_ABF1 PF04684.13 GBG63244.1 - 9.1 5.2 11.7 12 4.8 11.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 GBG63245.1 - 0.16 10.7 2.2 0.24 10.1 2.2 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 GBG63245.1 - 7.3 6.6 10.1 0.74 9.9 0.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RVT_1 PF00078.27 GBG63246.1 - 4.5e-12 46.0 0.2 1e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG63246.1 - 0.0016 18.7 1.1 0.0051 17.1 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG63246.1 - 0.56 10.3 5.4 0.74 9.9 4.1 1.9 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF659 PF04937.15 GBG63247.1 - 4.4e-35 120.8 0.0 7.2e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63247.1 - 6.1e-11 42.0 0.1 1.4e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF445 PF04286.12 GBG63247.1 - 0.47 10.2 1.5 13 5.5 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF445) RVT_1 PF00078.27 GBG63248.1 - 2e-25 89.6 0.1 3e-25 89.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63248.1 - 9.5e-17 60.9 0.0 2.6e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63248.1 - 8.4e-09 35.7 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG63248.1 - 4.2e-07 30.2 0.0 9.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG63249.1 - 0.013 15.8 4.4 2.8 8.3 0.1 3.6 3 1 1 4 4 4 0 Retrotransposon gag protein PIEZO PF15917.5 GBG63249.1 - 0.18 11.3 4.6 0.34 10.3 4.6 1.4 1 0 0 1 1 1 0 Piezo CLZ PF16526.5 GBG63249.1 - 0.19 12.1 3.6 3.6 8.0 0.5 3.6 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FAM76 PF16046.5 GBG63249.1 - 0.28 10.5 2.6 0.41 10.0 2.6 1.3 1 0 0 1 1 1 0 FAM76 protein Flagellin_C PF00700.21 GBG63249.1 - 3.7 8.0 9.4 17 5.9 3.1 3.3 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region DUF1664 PF07889.12 GBG63250.1 - 0.62 10.1 6.1 0.33 11.0 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5069 PF16798.5 GBG63250.1 - 4 7.7 8.6 0.11 12.6 1.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5069) RT_RNaseH_2 PF17919.1 GBG63251.1 - 7.5e-24 83.7 0.0 1.6e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63251.1 - 9.5e-22 77.4 0.1 9.2e-14 51.7 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH PF17917.1 GBG63251.1 - 3.7e-21 75.4 0.0 7.9e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG63251.1 - 1.8e-14 54.1 0.0 1.5e-06 28.7 0.0 2.8 3 0 0 3 3 2 2 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG63251.1 - 1.9e-14 53.5 4.9 1.8e-11 44.0 0.3 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG63251.1 - 5.2e-13 49.5 0.0 5.9e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease RVT_1 PF00078.27 GBG63251.1 - 1.4e-09 37.9 0.0 5.6e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG63251.1 - 9.5e-09 35.1 0.0 6.1e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63251.1 - 2.1e-07 30.8 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease DUF1758 PF05585.12 GBG63251.1 - 0.00023 21.0 0.0 0.078 12.7 0.0 2.7 3 0 0 3 3 3 1 Putative peptidase (DUF1758) TOBE_2 PF08402.10 GBG63251.1 - 0.0097 16.1 0.9 4.7 7.5 0.0 3.2 3 0 0 3 3 3 1 TOBE domain RT_RNaseH PF17917.1 GBG63252.1 - 2.8e-22 79.0 0.0 6.6e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63252.1 - 7.8e-20 70.8 0.0 1.6e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63252.1 - 1.6e-15 57.3 0.0 9.6e-14 51.6 0.0 2.5 1 1 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG63252.1 - 2.8e-12 46.5 0.1 8.2e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG63252.1 - 0.0071 16.1 0.0 0.027 14.2 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain SgrT PF15894.5 GBG63252.1 - 0.053 13.5 0.0 19 5.3 0.0 2.6 2 0 0 2 2 2 0 Inhibitor of glucose uptake transporter SgrT Retrotrans_gag PF03732.17 GBG63253.1 - 0.025 14.8 1.4 0.025 14.8 1.4 3.0 2 2 1 3 3 3 0 Retrotransposon gag protein Phosphodiest PF01663.22 GBG63253.1 - 0.22 11.1 1.1 3.8 7.0 0.0 2.7 2 1 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase NPV_P10 PF05531.12 GBG63253.1 - 0.93 10.0 3.1 5.4 7.6 0.5 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG63254.1 - 2.5e-33 115.4 0.2 3.8e-33 114.9 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG63256.1 - 2.1e-15 56.9 0.0 3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG63257.1 - 0.00082 18.9 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG63257.1 - 0.0025 18.3 0.0 0.0078 16.8 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63257.1 - 0.23 12.1 0.0 0.65 10.7 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Orthopox_F14 PF06076.12 GBG63258.1 - 0.082 13.2 0.4 0.19 12.0 0.4 1.6 1 0 0 1 1 1 0 Orthopoxvirus F14 protein RVP_2 PF08284.11 GBG63259.1 - 4e-08 33.1 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63259.1 - 1.2e-07 32.2 0.0 3.4e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63259.1 - 9.3e-06 26.1 0.0 3.7e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG63259.1 - 0.00048 19.9 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease TRPM_tetra PF16519.5 GBG63259.1 - 0.053 13.6 0.2 0.31 11.2 0.2 2.2 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Retrotrans_gag PF03732.17 GBG63259.1 - 0.26 11.6 3.6 0.98 9.7 0.0 3.3 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG63260.1 - 1.2e-23 83.3 0.0 2.8e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63260.1 - 1.6e-16 60.2 0.0 3.2e-16 59.2 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63260.1 - 1.5e-14 53.9 0.2 2.9e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Nif11 PF07862.11 GBG63260.1 - 0.092 13.1 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 Nif11 domain PRTP PF01366.18 GBG63261.1 - 1.1 7.2 8.3 1.5 6.8 8.3 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein UPF0242 PF06785.11 GBG63261.1 - 3.5 7.7 27.1 0.045 13.9 4.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RT_RNaseH_2 PF17919.1 GBG63262.1 - 7.2e-33 112.6 0.0 1.6e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63262.1 - 2.9e-30 104.6 0.1 6.5e-30 103.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63262.1 - 7.8e-18 64.8 0.1 1.4e-17 63.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG63262.1 - 9.9e-18 64.0 0.5 2.2e-17 62.9 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63262.1 - 4.7e-15 55.8 1.1 1.5e-14 54.2 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG63262.1 - 0.005 17.0 0.0 0.018 15.2 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG63263.1 - 9.1e-24 84.2 0.0 1.7e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG63263.1 - 2.4e-10 40.3 0.3 8.5e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG63263.1 - 9.4e-09 35.5 0.0 2.2e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HhH-GPD PF00730.25 GBG63263.1 - 0.0012 19.2 0.0 0.0072 16.8 0.0 2.3 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein zf-H2C2 PF09337.10 GBG63263.1 - 0.037 14.2 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger DUF1682 PF07946.14 GBG63263.1 - 0.25 10.5 3.5 0.66 9.1 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Herpes_UL25 PF01499.16 GBG63265.1 - 0.75 8.2 8.9 1.1 7.7 8.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family TTKRSYEDQ PF10212.9 GBG63265.1 - 4.6 6.1 11.6 7.2 5.5 11.6 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein PA26 PF04636.13 GBG63265.1 - 5 5.9 11.5 7.2 5.4 11.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PRTP PF01366.18 GBG63265.1 - 8.8 4.2 8.5 13 3.6 8.5 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RVP_2 PF08284.11 GBG63266.1 - 3.5e-09 36.5 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG63266.1 - 4.7e-09 36.1 0.3 0.00036 20.1 0.1 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG63266.1 - 2e-05 25.1 0.1 0.0001 22.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG63266.1 - 3.8e-05 23.5 0.0 9.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63266.1 - 0.00014 22.3 0.0 0.00033 21.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-4CXXC_R1 PF10497.9 GBG63266.1 - 0.0099 16.1 6.9 0.032 14.4 6.9 1.8 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 FANCI_S1-cap PF14674.6 GBG63266.1 - 1 9.5 3.0 4.7 7.4 0.2 2.6 2 0 0 2 2 2 0 FANCI solenoid 1 cap CDC27 PF09507.10 GBG63267.1 - 6.9 5.9 45.0 8.6 5.6 45.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 gag-asp_proteas PF13975.6 GBG63268.1 - 7.3e-09 36.1 0.1 2.5e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63268.1 - 7.6e-06 26.5 0.0 1.9e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG63268.1 - 0.0041 16.7 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG63268.1 - 0.0045 16.8 0.5 0.015 15.1 0.2 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG63268.1 - 0.033 14.5 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG63268.1 - 0.56 10.4 5.5 2.3 8.4 0.9 2.8 2 0 0 2 2 2 0 Zinc knuckle RCC1 PF00415.18 GBG63269.1 - 2.6e-44 149.6 10.5 7.4e-12 45.7 0.0 4.3 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG63269.1 - 8.3e-21 73.3 14.2 3.2e-08 33.1 0.4 5.6 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 GBG63269.1 - 2.5e-14 53.2 1.4 4.3e-10 39.6 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GBG63269.1 - 2.3e-11 44.0 0.4 6.1e-06 26.7 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GBG63269.1 - 4.5e-09 36.4 3.1 8.7e-07 29.1 0.2 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 GBG63269.1 - 7.4e-08 32.9 0.0 2.5e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GBG63269.1 - 9.8e-06 25.6 1.8 0.018 15.5 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat DUF1459 PF07312.11 GBG63269.1 - 0.076 13.2 3.6 0.58 10.4 0.0 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF1459) RT_RNaseH_2 PF17919.1 GBG63270.1 - 8.9e-23 80.2 0.0 1.8e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63270.1 - 2.8e-22 79.3 0.1 7.1e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63270.1 - 3.9e-22 78.5 0.0 8.5e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63270.1 - 1.1e-19 70.2 0.4 2.6e-19 69.0 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Tudor-knot PF11717.8 GBG63270.1 - 3.2e-05 23.7 0.0 8.9e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG63270.1 - 0.00091 19.1 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG63271.1 - 1.8e-28 99.6 1.0 1.2e-10 41.3 0.0 3.5 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG63271.1 - 0.0028 17.9 0.2 0.016 15.4 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein RCC1_2 PF13540.6 GBG63271.1 - 0.0079 16.0 0.3 0.02 14.7 0.3 1.7 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat APG17 PF04108.12 GBG63271.1 - 0.11 11.6 0.2 0.2 10.8 0.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Lys-AminoMut_A PF09043.11 GBG63271.1 - 0.49 8.8 1.7 0.71 8.3 1.7 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit RVT_1 PF00078.27 GBG63272.1 - 9.1e-26 90.7 0.0 1.8e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63272.1 - 6.9e-18 64.5 0.0 1.7e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63272.1 - 6.8e-09 36.0 0.0 1.7e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG63272.1 - 8.3e-08 32.8 0.0 2.9e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63272.1 - 7.6e-07 29.6 0.0 2.2e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63272.1 - 0.00028 20.7 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63272.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG63272.1 - 0.0078 16.5 2.5 0.22 11.8 0.0 3.7 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG63272.1 - 0.88 8.9 9.5 24 4.2 8.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 GBG63272.1 - 3.6 7.9 8.1 19 5.5 7.1 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RT_RNaseH_2 PF17919.1 GBG63273.1 - 2.3e-29 101.3 0.0 2.2e-28 98.2 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63273.1 - 1e-28 99.7 0.1 1.1e-27 96.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63273.1 - 1.6e-18 66.6 0.7 3.3e-18 65.5 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63273.1 - 1.5e-17 63.9 0.0 4e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG63273.1 - 2.2e-12 47.0 0.0 4.8e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG63273.1 - 1.1e-06 28.5 0.0 2.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63273.1 - 1.4e-05 25.6 0.0 4.3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63273.1 - 0.00064 20.2 0.0 0.002 18.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG63273.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG63273.1 - 0.05 13.8 0.2 0.14 12.4 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Josephin PF02099.17 GBG63275.1 - 0.033 14.3 0.0 0.075 13.1 0.0 1.5 1 1 0 1 1 1 0 Josephin RVT_1 PF00078.27 GBG63276.1 - 1.1e-28 100.3 0.1 2.1e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG63276.1 - 0.0023 18.2 2.9 0.25 11.6 0.0 4.1 4 0 0 4 4 4 1 Retrotransposon gag protein DUF3006 PF11213.8 GBG63276.1 - 0.036 14.3 1.7 0.18 12.0 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) RVT_1 PF00078.27 GBG63278.1 - 2e-21 76.6 0.0 1e-17 64.4 0.0 2.8 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) LSDAT_prok PF18171.1 GBG63278.1 - 0.057 12.6 0.1 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote DUF659 PF04937.15 GBG63279.1 - 0.00027 20.8 0.0 0.00062 19.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63279.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG63280.1 - 0.053 13.4 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Stig1 PF04885.13 GBG63282.1 - 1.3e-18 67.8 79.4 1.1e-06 29.2 15.3 3.7 4 1 1 5 5 5 3 Stigma-specific protein, Stig1 NPAT_C PF15712.5 GBG63282.1 - 0.24 10.0 9.6 2 7.0 0.0 2.1 2 0 0 2 2 2 0 NPAT C terminus RuBisCO_small PF00101.20 GBG63284.1 - 2e-41 139.9 0.0 2.8e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain DUF16 PF01519.16 GBG63285.1 - 1.4 9.4 6.1 0.42 11.1 0.3 2.8 3 1 1 4 4 4 0 Protein of unknown function DUF16 SusD_RagB PF07980.11 GBG63286.1 - 0.033 13.8 0.1 0.041 13.5 0.1 1.1 1 0 0 1 1 1 0 SusD family RVT_1 PF00078.27 GBG63287.1 - 2.1e-28 99.4 0.1 4.3e-28 98.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63287.1 - 4.9e-26 90.7 0.0 1.7e-25 89.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63287.1 - 1.3e-24 86.5 0.0 3.8e-24 85.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63287.1 - 3.4e-16 59.1 0.0 8.6e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63287.1 - 0.0015 18.7 0.1 0.0074 16.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG63287.1 - 0.0045 17.2 0.1 0.0045 17.2 0.1 3.4 3 0 0 3 3 3 1 Retrotransposon gag protein FPP PF05911.11 GBG63287.1 - 0.018 13.2 1.6 0.17 10.0 0.1 2.5 3 0 0 3 3 3 0 Filament-like plant protein, long coiled-coil Retrotrans_gag PF03732.17 GBG63288.1 - 0.00086 19.5 0.1 0.0023 18.2 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein fn3_4 PF16794.5 GBG63288.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Fibronectin-III type domain RVT_1 PF00078.27 GBG63289.1 - 1.2e-20 74.0 0.2 1.2e-19 70.7 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63289.1 - 1.4e-09 37.8 0.2 9.1e-09 35.3 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63289.1 - 0.013 15.8 0.0 0.041 14.2 0.0 1.9 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Trimer_CC PF08954.11 GBG63289.1 - 0.013 15.0 0.4 7.3 6.2 0.2 2.7 1 1 1 2 2 2 0 Trimerisation motif DUF4187 PF13821.6 GBG63289.1 - 0.29 11.0 6.4 0.061 13.1 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) AMP-binding_C PF13193.6 GBG63290.1 - 0.11 13.5 0.2 0.4 11.7 0.0 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain RT_RNaseH PF17917.1 GBG63291.1 - 1.1e-23 83.5 0.0 4e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63291.1 - 1.2e-21 76.6 0.0 2.5e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63291.1 - 6e-13 48.7 0.2 1.4e-12 47.5 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63291.1 - 5.9e-08 32.5 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63291.1 - 1.3e-07 31.9 0.0 2.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63291.1 - 0.03 14.6 0.5 0.064 13.5 0.5 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Toprim_N PF08275.11 GBG63292.1 - 3.1e-05 24.0 29.6 56 3.8 0.0 16.1 3 3 16 20 20 20 0 DNA primase catalytic core, N-terminal domain PapC_C PF13953.6 GBG63292.1 - 0.0076 16.0 99.0 1 9.2 0.2 20.1 2 2 23 25 25 25 10 PapC C-terminal domain RTA1 PF04479.13 GBG63292.1 - 0.038 13.6 40.3 63 3.1 0.0 16.2 6 5 16 22 22 22 0 RTA1 like protein Methyltransf_1N PF02870.15 GBG63292.1 - 1.1 10.1 20.8 1.1e+02 3.8 0.0 9.9 9 4 5 14 14 14 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DCR PF14047.6 GBG63292.1 - 8.2 6.7 26.6 20 5.5 0.1 11.0 7 6 13 20 20 20 0 Dppa2/4 conserved region gag-asp_proteas PF13975.6 GBG63293.1 - 0.026 15.1 0.0 0.081 13.5 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG63293.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG63293.1 - 0.074 13.3 0.1 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2621 PF11084.8 GBG63294.1 - 0.072 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Ribosomal_L35p PF01632.19 GBG63295.1 - 1.1 9.8 5.7 0.47 11.0 1.3 2.8 2 0 0 2 2 2 0 Ribosomal protein L35 RT_RNaseH_2 PF17919.1 GBG63296.1 - 1.8e-27 95.3 0.0 3.1e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63296.1 - 1.2e-23 83.3 0.0 2.4e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63296.1 - 2.9e-11 43.3 0.1 4.3e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5627 PF18620.1 GBG63297.1 - 3.3 7.6 8.6 0.42 10.5 3.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5627) RVT_1 PF00078.27 GBG63300.1 - 5.1e-27 94.8 0.1 8.4e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63300.1 - 3.6e-26 91.1 0.0 1.3e-11 44.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63300.1 - 3e-16 59.6 0.0 7.1e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63300.1 - 2.7e-13 49.8 0.2 2.7e-13 49.8 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG63300.1 - 9.2e-11 42.0 0.0 4.2e-10 39.8 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63300.1 - 0.00065 19.9 0.0 0.0017 18.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF4399 PF14347.6 GBG63300.1 - 0.12 12.8 0.0 0.41 11.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) GrpE PF01025.19 GBG63301.1 - 0.034 13.8 0.6 0.052 13.2 0.6 1.2 1 0 0 1 1 1 0 GrpE DUF2870 PF11069.8 GBG63301.1 - 0.17 12.3 1.1 0.38 11.2 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DUF4175 PF13779.6 GBG63301.1 - 1 7.2 12.6 1.5 6.7 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RVT_1 PF00078.27 GBG63302.1 - 1.1e-28 100.2 0.1 1.6e-28 99.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG63302.1 - 0.021 14.0 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 RVT_1 PF00078.27 GBG63303.1 - 1.6e-23 83.4 0.0 3.2e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG63303.1 - 4.1e-06 26.6 0.0 2e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63303.1 - 7.7e-06 26.5 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63303.1 - 9e-05 23.0 0.0 0.00021 21.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG63303.1 - 0.0083 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG63303.1 - 0.11 12.8 0.0 0.43 10.9 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG63306.1 - 1.3e-34 119.6 0.1 2e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63306.1 - 1.1e-14 54.2 0.0 3.1e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63306.1 - 2.4e-06 27.8 0.0 5.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LisH PF08513.11 GBG63306.1 - 0.00056 19.8 0.1 0.002 18.0 0.1 2.0 1 0 0 1 1 1 1 LisH K-box PF01486.17 GBG63306.1 - 0.9 9.7 9.2 0.039 14.1 0.3 3.1 3 0 0 3 3 3 0 K-box region UFC1 PF08694.11 GBG63308.1 - 5.1e-85 282.8 0.2 6.1e-85 282.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 GBG63308.1 - 0.00093 18.9 0.2 0.0051 16.5 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GBG63308.1 - 0.041 14.2 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain Myb_DNA-bind_4 PF13837.6 GBG63309.1 - 1.7e-05 25.1 0.2 3e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG63309.1 - 0.00024 21.1 0.8 0.00024 21.1 0.8 1.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG63309.1 - 0.097 12.9 2.1 0.27 11.4 2.1 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG63311.1 - 0.003 17.6 0.9 0.0045 17.0 0.9 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG63312.1 - 1.6e-13 50.8 0.0 3.2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63312.1 - 0.00019 21.2 0.8 0.00035 20.3 0.8 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG63313.1 - 1.4e-27 96.7 0.0 2.3e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63313.1 - 9.9e-12 44.8 0.0 3e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63313.1 - 0.022 15.0 0.1 0.082 13.2 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG63313.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RWD PF05773.22 GBG63314.1 - 3.8e-19 69.1 0.0 1.2e-18 67.5 0.0 1.8 1 1 0 1 1 1 1 RWD domain IBR PF01485.21 GBG63314.1 - 1.5e-16 60.4 35.9 3.3e-11 43.2 4.8 4.8 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain TPR_11 PF13414.6 GBG63314.1 - 5.8e-12 45.1 1.0 1.2e-06 28.1 0.4 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.17 GBG63314.1 - 1.6e-10 40.3 11.2 0.0004 20.3 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG63314.1 - 1.9e-10 40.1 10.1 9.8e-05 22.0 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG63314.1 - 2.4e-08 34.1 17.6 0.046 14.6 0.1 5.9 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 GBG63314.1 - 8.9e-08 32.7 14.1 1.8e-05 25.2 0.4 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG63314.1 - 6.3e-07 29.3 0.1 0.017 15.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG63314.1 - 6.7e-07 29.7 13.7 4.6e-05 23.8 1.3 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG63314.1 - 6.8e-05 22.8 2.2 0.29 11.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-RING_5 PF14634.6 GBG63314.1 - 0.00011 22.1 5.6 0.00011 22.1 5.6 4.3 4 1 1 5 5 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG63314.1 - 0.0002 21.3 0.7 0.0002 21.3 0.7 3.9 3 1 1 4 4 2 1 RING-type zinc-finger TPR_9 PF13371.6 GBG63314.1 - 0.00023 21.2 6.5 0.00046 20.3 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 GBG63314.1 - 0.00095 19.5 5.7 0.00095 19.5 5.7 4.2 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4 PF00097.25 GBG63314.1 - 0.0016 18.3 4.5 0.0016 18.3 4.5 4.2 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.6 GBG63314.1 - 0.13 12.6 10.7 2.7 8.3 0.4 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG63314.1 - 6.5 6.8 13.4 12 6.0 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RT_RNaseH PF17917.1 GBG63315.1 - 3.4e-23 81.9 0.0 7.3e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63315.1 - 2.8e-14 52.9 0.0 6.2e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG63315.1 - 0.0019 18.5 0.1 0.006 16.8 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG63315.1 - 0.0098 15.9 2.4 0.023 14.8 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG63315.1 - 0.012 16.3 0.0 0.038 14.6 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG63315.1 - 0.083 13.5 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Mito_fiss_reg PF05308.11 GBG63315.1 - 0.1 12.6 2.3 0.27 11.3 2.3 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4746 PF15928.5 GBG63315.1 - 9.8 5.5 16.8 9.8 5.5 14.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Not1 PF04054.15 GBG63316.1 - 9e-155 515.1 2.8 1.8e-154 514.1 2.8 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 GBG63316.1 - 1.1e-91 306.3 2.8 2.4e-91 305.1 2.8 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 GBG63316.1 - 2.4e-66 222.5 0.6 2.4e-66 222.5 0.6 3.0 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 GBG63316.1 - 4e-49 166.3 1.1 2.7e-48 163.6 0.7 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 GBG63316.1 - 1e-42 145.8 0.1 1e-42 145.8 0.1 3.1 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF2722 PF10846.8 GBG63316.1 - 0.1 11.5 8.1 0.17 10.8 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF1289 PF06945.13 GBG63316.1 - 0.21 11.4 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DUF713 PF05218.14 GBG63316.1 - 0.41 10.4 2.5 4.6 6.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF713) Suf PF05843.14 GBG63316.1 - 2.5 8.0 5.1 6.7 6.6 5.1 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pkinase PF00069.25 GBG63318.1 - 3.3e-51 174.2 0.0 8.1e-51 172.9 0.0 1.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63318.1 - 1.9e-29 102.8 0.0 6.6e-29 101.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase SBP_bac_6 PF13343.6 GBG63318.1 - 6.6e-26 91.2 0.0 7e-20 71.5 0.0 2.7 2 1 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 GBG63318.1 - 3e-13 50.2 0.0 5.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Pkinase_fungal PF17667.1 GBG63318.1 - 0.024 13.4 0.0 0.084 11.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase SUIM_assoc PF16619.5 GBG63318.1 - 0.17 12.0 7.3 0.15 12.2 4.8 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GBG63318.1 - 2.3 7.8 9.2 5.2 6.6 9.2 1.5 1 0 0 1 1 1 0 Spt20 family Elf1 PF05129.13 GBG63319.1 - 2.1e-29 101.4 2.0 2.4e-29 101.2 2.0 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_CPXG PF14255.6 GBG63319.1 - 0.043 13.7 3.1 1.8 8.5 0.2 2.3 2 1 0 2 2 2 0 Cysteine-rich CPXCG zf-Di19 PF05605.12 GBG63319.1 - 0.064 13.6 4.7 0.69 10.3 4.7 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding UBZ_FAAP20 PF15750.5 GBG63319.1 - 0.09 12.7 0.5 12 6.0 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger DUF1771 PF08590.10 GBG63320.1 - 7.5e-20 71.1 9.2 7.5e-20 71.1 9.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 GBG63320.1 - 7.5e-08 32.6 0.9 2e-07 31.3 0.9 1.7 1 0 0 1 1 1 1 Smr domain PAM2 PF07145.15 GBG63320.1 - 0.00064 19.2 0.7 0.0024 17.5 0.7 2.0 1 0 0 1 1 1 1 Ataxin-2 C-terminal region RVT_1 PF00078.27 GBG63321.1 - 1.6e-30 106.3 0.0 2.4e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG63321.1 - 0.013 16.1 0.0 0.034 14.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Hormone_3 PF00159.18 GBG63321.1 - 0.089 12.9 0.3 0.49 10.5 0.3 2.3 1 0 0 1 1 1 0 Pancreatic hormone peptide SDA1 PF05285.12 GBG63322.1 - 0.02 14.3 46.9 0.024 14.1 46.9 1.1 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 GBG63322.1 - 1.9 7.6 13.6 2.1 7.5 13.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GBG63322.1 - 3.9 6.1 22.3 4.7 5.9 22.3 1.0 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG63322.1 - 9.2 4.3 56.6 12 4.0 56.6 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG63323.1 - 4.3e-35 121.2 0.0 7.4e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63323.1 - 1.1e-30 105.6 0.0 2.7e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63323.1 - 4.9e-30 103.9 0.0 9.5e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63323.1 - 1.7e-16 60.0 0.4 4.1e-16 58.8 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG63323.1 - 0.002 18.3 0.0 0.0096 16.1 0.0 2.3 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG63323.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Nop14 PF04147.12 GBG63324.1 - 0.63 8.2 23.6 0.96 7.6 23.6 1.2 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 GBG63324.1 - 1.1 9.3 16.9 1.9 8.6 16.9 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Myb_DNA-bind_4 PF13837.6 GBG63325.1 - 0.0008 19.7 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SPAN-X PF07458.12 GBG63325.1 - 0.14 12.6 1.9 0.23 11.9 0.7 1.9 2 0 0 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome Myb_DNA-bind_4 PF13837.6 GBG63326.1 - 0.024 15.0 0.3 0.59 10.5 0.1 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rit1_C PF17184.4 GBG63326.1 - 0.2 11.1 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Rit1 N-terminal domain Pkinase PF00069.25 GBG63327.1 - 3.8e-25 88.8 0.2 5.4e-12 45.6 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63327.1 - 1.3e-11 44.3 0.1 8.9e-05 21.9 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RT_RNaseH_2 PF17919.1 GBG63328.1 - 1e-30 105.7 0.0 6.6e-30 103.1 0.0 2.4 3 1 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63328.1 - 2.8e-25 88.6 0.0 2e-24 85.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63328.1 - 1.5e-08 34.4 0.1 2.8e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACC_epsilon PF13822.6 GBG63329.1 - 7.5 7.3 14.8 11 6.8 0.0 4.4 4 0 0 4 4 4 0 Acyl-CoA carboxylase epsilon subunit Pkinase_Tyr PF07714.17 GBG63332.1 - 2e-41 142.0 0.0 2.9e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG63332.1 - 2.7e-40 138.4 0.0 3.8e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG63332.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG63332.1 - 0.53 9.0 0.0 0.53 9.0 0.0 3.6 4 0 0 4 4 4 0 Fungal protein kinase Vfa1 PF08432.10 GBG63333.1 - 0.1 12.9 9.5 0.3 11.4 9.5 1.6 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 GBG63333.1 - 0.63 8.2 32.5 0.72 8.0 32.5 1.0 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 GBG63333.1 - 0.81 9.5 8.0 0.9 9.3 8.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Nup192 PF11894.8 GBG63334.1 - 6.4e-108 361.8 2.7 2.6e-71 240.4 0.0 3.3 3 1 0 3 3 3 3 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 GBG63334.1 - 4.5e-07 28.2 0.0 0.0065 14.5 0.0 2.5 3 0 0 3 3 3 2 Nucleoporin subcomplex protein binding to Pom34 PIN PF01850.21 GBG63334.1 - 0.0026 18.3 0.1 0.01 16.4 0.1 2.0 1 0 0 1 1 1 1 PIN domain HIGH_NTase1_ass PF16581.5 GBG63334.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region RT_RNaseH_2 PF17919.1 GBG63335.1 - 1.2e-28 99.1 0.0 2.4e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63335.1 - 2.5e-24 86.0 0.0 4.2e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63335.1 - 1.2e-23 83.4 0.0 3.1e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63335.1 - 4.5e-08 33.3 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG63335.1 - 0.0042 17.7 0.0 0.0087 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63335.1 - 0.0063 17.0 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG63335.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Hydrolase PF00702.26 GBG63336.1 - 0.00072 19.9 0.0 0.0016 18.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RPN6_C_helix PF18503.1 GBG63338.1 - 0.023 14.4 1.9 21 5.0 0.1 3.5 3 0 0 3 3 3 0 26S proteasome subunit RPN6 C-terminal helix domain Ole-e-6 PF09253.10 GBG63338.1 - 1.4 8.9 6.6 2.7 8.0 1.0 2.9 3 0 0 3 3 3 0 Pollen allergen ole e 6 Pkinase PF00069.25 GBG63339.1 - 3.9e-68 229.7 0.0 5.2e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63339.1 - 7.5e-52 176.2 0.0 1.6e-51 175.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG63339.1 - 0.00024 20.5 0.0 0.0081 15.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GBG63339.1 - 0.00061 18.7 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG63339.1 - 0.051 13.5 0.3 10 6.0 0.0 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 GBG63339.1 - 0.2 11.0 0.1 0.46 9.8 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abi_2 PF07751.11 GBG63339.1 - 0.22 11.8 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 Abi-like protein Haspin_kinase PF12330.8 GBG63339.1 - 0.24 10.3 0.0 0.6 9.0 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Elong_Iki1 PF10483.9 GBG63340.1 - 5.5e-11 42.5 1.0 8.2e-05 22.2 0.1 3.0 2 1 0 3 3 3 2 Elongator subunit Iki1 YqjK PF13997.6 GBG63340.1 - 0.017 15.3 0.3 0.038 14.2 0.3 1.5 1 0 0 1 1 1 0 YqjK-like protein DUF3499 PF12005.8 GBG63340.1 - 0.09 13.4 2.1 3.8 8.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Radial_spoke PF04712.12 GBG63340.1 - 0.74 8.7 4.0 1 8.2 4.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein SPX PF03105.19 GBG63340.1 - 2 8.2 17.1 0.24 11.3 12.7 1.5 2 0 0 2 2 2 0 SPX domain DUF4519 PF15012.6 GBG63340.1 - 3.6 7.8 6.5 7.1 6.9 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF4530 PF15039.6 GBG63340.1 - 5.3 7.2 7.7 46 4.2 7.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) Aminotran_3 PF00202.21 GBG63341.1 - 1.1e-116 389.9 0.0 1.5e-116 389.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III MCM PF00493.23 GBG63342.1 - 1.5e-100 334.9 0.0 2.4e-100 334.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GBG63342.1 - 5.8e-38 129.6 0.1 1e-37 128.8 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GBG63342.1 - 2.8e-28 98.2 1.2 6.6e-28 97.0 1.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GBG63342.1 - 7.5e-10 39.3 0.0 7.5e-10 39.3 0.0 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 GBG63342.1 - 4.8e-06 26.1 0.0 1.7e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GBG63342.1 - 0.00033 20.7 0.0 0.00091 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GBG63342.1 - 0.0027 17.6 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF659 PF04937.15 GBG63343.1 - 9.2e-24 84.0 1.0 1.2e-13 51.2 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63343.1 - 1.6e-05 24.6 0.4 3.9e-05 23.4 0.4 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HC2 PF07382.11 GBG63344.1 - 8.6 6.4 25.1 12 5.9 25.1 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 CTD PF12815.7 GBG63344.1 - 8.8 7.0 7.5 4e+02 1.7 7.5 2.2 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 YpzI PF14140.6 GBG63347.1 - 0.019 14.7 0.4 5.1 6.9 0.0 2.2 2 0 0 2 2 2 0 YpzI-like protein RVT_1 PF00078.27 GBG63348.1 - 3.1e-28 98.8 0.1 6.6e-28 97.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG63348.1 - 7.3e-07 29.7 0.0 7.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63348.1 - 2.2e-05 24.9 0.0 6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63348.1 - 0.00046 20.0 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63348.1 - 0.0014 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG63348.1 - 0.0018 18.5 0.0 0.0095 16.2 0.0 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein Hist_deacetyl PF00850.19 GBG63349.1 - 3.3e-13 49.8 0.3 2.2e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylase domain TFIIA PF03153.13 GBG63349.1 - 0.93 9.4 12.2 1.2 9.1 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldo_ket_red PF00248.21 GBG63351.1 - 1.8e-64 217.7 0.0 3.4e-51 174.2 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family IMUP PF15761.5 GBG63351.1 - 0.6 10.8 5.3 0.95 10.2 4.4 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein Pkinase_Tyr PF07714.17 GBG63352.1 - 5.9e-32 111.0 0.0 1.7e-16 60.3 0.1 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG63352.1 - 1.6e-29 103.1 0.0 2.7e-14 53.2 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Acetyltransf_1 PF00583.25 GBG63353.1 - 1.2e-05 25.5 0.1 0.0001 22.5 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GBG63353.1 - 0.064 13.7 0.7 0.43 11.1 0.7 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-CCHC PF00098.23 GBG63354.1 - 0.031 14.4 2.1 0.067 13.3 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG63355.1 - 9e-24 83.8 0.0 1.6e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63355.1 - 1.3e-23 82.9 0.0 2.8e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63355.1 - 1.9e-14 53.5 0.3 3.9e-14 52.5 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63355.1 - 0.0014 18.8 0.0 0.0041 17.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63355.1 - 0.019 15.2 0.7 0.039 14.2 0.7 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Presenilin PF01080.17 GBG63356.1 - 2.4e-45 155.0 0.0 2.6e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Presenilin DUF659 PF04937.15 GBG63357.1 - 1.2e-30 106.4 0.5 2.5e-30 105.4 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63357.1 - 7.9e-07 28.8 0.3 1.8e-05 24.4 0.3 2.6 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region CytB6-F_Fe-S PF08802.10 GBG63357.1 - 0.059 13.4 0.1 0.22 11.6 0.1 2.0 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit DUF4825 PF16107.5 GBG63357.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4825) PQQ_3 PF13570.6 GBG63357.1 - 8.9 7.0 8.7 4.9 7.8 0.2 2.9 3 0 0 3 3 3 0 PQQ-like domain Asp_protease_2 PF13650.6 GBG63358.1 - 3.1e-06 27.7 0.0 9.2e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63358.1 - 4.7e-06 27.1 0.0 2.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63358.1 - 7.5e-05 22.5 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG63358.1 - 0.00035 20.8 5.2 0.0031 17.8 0.1 3.9 4 0 0 4 4 4 1 Retrotransposon gag protein SPARC_Ca_bdg PF10591.9 GBG63358.1 - 0.15 12.4 1.4 0.8 10.0 0.6 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region BLOC1_2 PF10046.9 GBG63358.1 - 0.45 10.8 3.6 1.9 8.8 1.1 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cons_hypoth95 PF03602.15 GBG63359.1 - 0.12 12.0 0.3 0.26 10.9 0.3 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF262 PF03235.14 GBG63359.1 - 0.47 10.6 7.2 4 7.5 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF262 SR-25 PF10500.9 GBG63360.1 - 7.1e-06 25.8 23.0 7.1e-06 25.8 23.0 1.5 2 0 0 2 2 1 1 Nuclear RNA-splicing-associated protein YL1 PF05764.13 GBG63360.1 - 0.00083 19.5 13.7 0.0011 19.1 13.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Eapp_C PF10238.9 GBG63360.1 - 0.001 19.2 3.4 0.0015 18.6 3.4 1.4 1 0 0 1 1 1 1 E2F-associated phosphoprotein SpoIIP PF07454.11 GBG63360.1 - 0.008 15.7 6.2 0.011 15.2 6.2 1.3 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.10 GBG63360.1 - 0.0081 16.5 15.7 0.013 15.8 15.7 1.3 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.12 GBG63360.1 - 0.0091 15.4 15.8 0.013 14.9 15.8 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger ORC5_C PF14630.6 GBG63360.1 - 0.01 15.4 6.1 0.017 14.6 6.1 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus NARP1 PF12569.8 GBG63360.1 - 0.034 13.1 18.2 0.043 12.7 18.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3807 PF12720.7 GBG63360.1 - 0.062 13.6 15.5 0.099 12.9 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Tim54 PF11711.8 GBG63360.1 - 0.081 11.7 11.3 0.12 11.2 11.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3682 PF12446.8 GBG63360.1 - 0.2 12.2 4.4 0.38 11.2 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) RNA_pol_Rpc4 PF05132.14 GBG63360.1 - 0.22 12.0 12.5 0.39 11.1 12.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPN2_C PF18004.1 GBG63360.1 - 0.22 11.4 23.9 0.41 10.6 23.9 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain LMF1 PF06762.14 GBG63360.1 - 0.23 10.5 23.8 0.31 10.1 23.8 1.2 1 0 0 1 1 1 0 Lipase maturation factor FAM76 PF16046.5 GBG63360.1 - 0.27 10.6 23.8 0.34 10.2 23.8 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4604 PF15377.6 GBG63360.1 - 0.35 11.3 31.1 0.7 10.3 31.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PGA_cap PF09587.10 GBG63360.1 - 0.37 10.2 2.6 0.49 9.8 2.6 1.1 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF1764 PF08576.10 GBG63360.1 - 0.59 11.1 20.5 1.1 10.2 20.5 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) TraG_N PF07916.11 GBG63360.1 - 0.82 8.4 45.5 1.5 7.6 45.5 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region ORC_WH_C PF18137.1 GBG63360.1 - 1.2 9.2 12.0 2.1 8.4 12.0 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal SRP-alpha_N PF04086.13 GBG63360.1 - 1.2 9.0 20.4 1.7 8.5 20.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2339 PF10101.9 GBG63360.1 - 1.4 7.4 10.7 1.9 7.0 10.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Nop53 PF07767.11 GBG63360.1 - 1.5 8.1 29.6 2.1 7.7 29.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNA_polI_A34 PF08208.11 GBG63360.1 - 2.2 8.3 39.0 3.2 7.8 39.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PcfK PF14058.6 GBG63360.1 - 2.4 8.5 23.9 4.4 7.6 23.9 1.4 1 0 0 1 1 1 0 PcfK-like protein Mpp10 PF04006.12 GBG63360.1 - 3.6 5.9 26.6 4.8 5.5 26.6 1.1 1 0 0 1 1 1 0 Mpp10 protein Coilin_N PF15862.5 GBG63360.1 - 4.4 7.1 30.3 6.7 6.5 30.3 1.2 1 0 0 1 1 1 0 Coilin N-terminus AAA_11 PF13086.6 GBG63360.1 - 4.6 7.0 16.6 0.91 9.2 13.0 1.6 2 0 0 2 2 2 0 AAA domain YL1 PF05764.13 GBG63361.1 - 1.8e-08 34.8 35.6 1.8e-08 34.8 35.6 2.1 2 0 0 2 2 2 1 YL1 nuclear protein Presenilin PF01080.17 GBG63361.1 - 0.0036 16.1 19.7 0.0036 16.1 19.7 2.1 2 0 0 2 2 2 1 Presenilin ANAPC4_WD40 PF12894.7 GBG63361.1 - 0.058 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Mem_trans PF03547.18 GBG63361.1 - 0.34 9.3 1.1 0.3 9.4 1.1 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF572 PF04502.13 GBG63361.1 - 0.34 10.5 32.8 0.019 14.6 23.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) CDC45 PF02724.14 GBG63361.1 - 1.5 7.0 51.8 0.041 12.2 42.8 2.0 2 0 0 2 2 2 0 CDC45-like protein ASC PF00858.24 GBG63361.1 - 7 5.5 6.1 11 4.8 6.1 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel WD40 PF00400.32 GBG63362.1 - 0.068 14.1 0.0 17 6.5 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Transthyretin PF00576.21 GBG63362.1 - 0.099 13.3 0.0 0.15 12.8 0.0 1.3 1 0 0 1 1 1 0 HIUase/Transthyretin family TIP49 PF06068.13 GBG63363.1 - 5.3e-31 108.1 0.4 9.4e-31 107.3 0.1 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 GBG63363.1 - 1.6e-27 95.4 0.4 2.6e-27 94.8 0.4 1.3 1 0 0 1 1 1 1 TIP49 AAA-lid domain Mgm101p PF06420.12 GBG63363.1 - 0.041 13.4 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 CBFD_NFYB_HMF PF00808.23 GBG63363.1 - 0.15 12.4 0.4 0.27 11.5 0.4 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPR_12 PF13424.6 GBG63364.1 - 6.2e-39 132.1 21.7 1.2e-11 44.8 0.3 8.3 8 1 0 9 9 8 5 Tetratricopeptide repeat TPR_10 PF13374.6 GBG63364.1 - 2.5e-22 78.0 29.2 7.5e-07 28.8 0.2 11.5 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 GBG63364.1 - 2e-10 40.1 7.1 3 7.8 0.1 9.5 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 GBG63364.1 - 4e-10 39.1 3.9 6.3 7.3 0.0 9.6 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG63364.1 - 2.6e-09 36.5 9.3 7.8 6.9 0.2 9.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG63364.1 - 1.9e-07 30.6 15.6 2.4 8.4 0.0 10.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG63364.1 - 6.2e-05 23.5 39.6 5.3 8.1 0.0 12.1 12 2 2 14 14 12 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG63364.1 - 0.00039 19.9 2.4 0.00039 19.9 2.4 3.6 3 2 0 3 3 3 1 MalT-like TPR region TPR_19 PF14559.6 GBG63364.1 - 0.0004 20.8 21.1 0.33 11.5 0.1 7.2 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 GBG63364.1 - 0.017 15.7 30.1 1.8 9.4 0.2 9.7 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG63364.1 - 0.74 10.5 18.2 15 6.3 0.5 7.9 8 2 0 8 8 7 0 Tetratricopeptide repeat TPR_5 PF12688.7 GBG63364.1 - 1.8 8.8 12.6 3.5 7.9 0.2 5.2 6 1 0 6 6 5 0 Tetratrico peptide repeat DUF755 PF05501.11 GBG63364.1 - 2.7 8.3 11.0 6.4 7.1 11.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TPR_6 PF13174.6 GBG63364.1 - 3.4 8.5 4.1 90 4.0 0.0 4.7 7 0 0 7 7 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG63364.1 - 4.7 7.8 6.2 3.6e+02 1.9 0.0 5.9 9 0 0 9 9 5 0 Tetratricopeptide repeat RNase_HII PF01351.18 GBG63365.1 - 5.5e-14 52.5 0.1 5e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease HII RVT_1 PF00078.27 GBG63366.1 - 4.3e-28 98.4 0.1 6.8e-28 97.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63366.1 - 1.1e-09 38.5 0.1 2.5e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63366.1 - 2.4e-07 30.8 0.2 8.3e-07 29.0 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG63366.1 - 0.00089 19.3 0.0 0.0027 17.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63367.1 - 5.6e-14 52.0 0.0 1.8e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63367.1 - 3e-13 50.0 0.0 5.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63367.1 - 0.0094 16.2 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG63367.1 - 0.038 13.9 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 GBG63367.1 - 0.052 13.3 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain His_kinase PF06580.13 GBG63367.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase PAT1 PF09770.9 GBG63371.1 - 0.42 8.8 20.1 0.57 8.4 20.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 GBG63371.1 - 5.8 5.6 25.3 10 4.8 25.3 1.4 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 GBG63371.1 - 6.4 6.8 13.7 11 6.0 13.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RT_RNaseH_2 PF17919.1 GBG63373.1 - 6e-32 109.7 0.0 8e-17 61.1 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63373.1 - 2.3e-29 102.5 0.0 3.8e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63373.1 - 5.3e-26 90.9 0.0 1e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Es2 PF09751.9 GBG63374.1 - 0.00045 20.1 13.7 0.00054 19.8 13.7 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 LMBR1 PF04791.16 GBG63374.1 - 0.063 12.2 5.4 0.082 11.8 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC27 PF09507.10 GBG63374.1 - 1.1 8.6 29.3 1.4 8.2 29.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dapper PF15268.6 GBG63374.1 - 2.1 7.1 14.1 2.6 6.8 14.1 1.0 1 0 0 1 1 1 0 Dapper BSP_II PF05432.11 GBG63374.1 - 4.7 6.8 19.4 6.6 6.3 19.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF572 PF04502.13 GBG63377.1 - 0.92 9.1 9.8 1.4 8.5 9.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_60s PF00428.19 GBG63377.1 - 8.9 7.0 17.4 0.23 12.0 10.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nrap_D5 PF17406.2 GBG63378.1 - 3e-46 157.1 0.1 2.5e-45 154.1 0.1 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 GBG63378.1 - 2.3e-41 141.5 0.0 6.8e-41 140.0 0.0 1.7 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 GBG63378.1 - 4.5e-37 127.6 0.2 2.6e-35 121.9 0.1 3.2 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D2 PF17403.2 GBG63378.1 - 1.5e-36 125.4 0.4 1.8e-34 118.7 0.2 3.0 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 GBG63378.1 - 1.8e-27 96.3 0.3 4.8e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D6 PF17407.2 GBG63378.1 - 3.7e-15 56.3 0.0 1e-14 54.9 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 Retrotrans_gag PF03732.17 GBG63378.1 - 0.00071 19.8 1.1 0.0025 18.0 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG63378.1 - 1.3 9.5 3.9 2.2 8.8 0.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2390 PF09523.10 GBG63378.1 - 1.4 9.3 4.4 1.7 9.0 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Nrap_D5 PF17406.2 GBG63379.1 - 3e-46 157.1 0.1 2.5e-45 154.1 0.1 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 GBG63379.1 - 2.3e-41 141.5 0.0 6.8e-41 140.0 0.0 1.7 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 GBG63379.1 - 4.5e-37 127.6 0.2 2.6e-35 121.9 0.1 3.2 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D2 PF17403.2 GBG63379.1 - 1.5e-36 125.4 0.4 1.8e-34 118.7 0.2 3.0 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 GBG63379.1 - 1.8e-27 96.3 0.3 4.8e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D6 PF17407.2 GBG63379.1 - 3.7e-15 56.3 0.0 1e-14 54.9 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 Retrotrans_gag PF03732.17 GBG63379.1 - 0.00071 19.8 1.1 0.0025 18.0 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG63379.1 - 1.3 9.5 3.9 2.2 8.8 0.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2390 PF09523.10 GBG63379.1 - 1.4 9.3 4.4 1.7 9.0 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) RT_RNaseH PF17917.1 GBG63381.1 - 1e-18 67.5 0.0 2.5e-18 66.3 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63381.1 - 1e-10 41.5 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG63382.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Dimer_Tnp_hAT PF05699.14 GBG63383.1 - 0.00013 21.7 0.2 0.00023 20.9 0.2 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SDA1 PF05285.12 GBG63384.1 - 2.4e-07 30.5 38.5 2.7e-07 30.4 38.5 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG63384.1 - 0.095 10.9 52.8 0.14 10.4 52.8 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG63384.1 - 0.59 9.4 45.0 0.76 9.0 45.0 1.1 1 0 0 1 1 1 0 BUD22 WSD PF15613.6 GBG63385.1 - 5.5e-22 78.1 0.0 5.5e-22 78.1 0.0 4.5 5 2 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif CRAL_TRIO PF00650.20 GBG63385.1 - 1.1e-14 54.5 0.0 1.9e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain WHIM1 PF15612.6 GBG63385.1 - 8.1e-06 25.2 0.8 2e-05 24.0 0.8 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD PF00628.29 GBG63385.1 - 1e-05 25.3 11.0 2.5e-05 24.1 11.0 1.7 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 GBG63385.1 - 0.00043 20.5 0.5 0.0052 17.1 0.0 2.4 2 0 0 2 2 2 1 DDT domain Zf_RING PF16744.5 GBG63385.1 - 0.0027 17.8 8.7 0.0089 16.1 8.7 1.8 1 0 0 1 1 1 1 KIAA1045 RING finger DUF866 PF05907.13 GBG63385.1 - 0.046 13.6 3.1 0.14 12.1 3.1 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) PHD_4 PF16866.5 GBG63385.1 - 0.15 12.1 9.7 0.35 11.0 8.0 2.6 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 GBG63385.1 - 9.6 6.2 12.9 1.1 9.1 6.0 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CCHC PF00098.23 GBG63386.1 - 9.6e-07 28.6 3.6 2.4e-06 27.3 3.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG63386.1 - 0.026 14.5 2.2 0.065 13.2 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Pkinase_fungal PF17667.1 GBG63386.1 - 0.042 12.6 2.7 0.056 12.2 2.7 1.4 1 0 0 1 1 1 0 Fungal protein kinase zf-CCHC_2 PF13696.6 GBG63386.1 - 0.083 12.7 2.5 0.18 11.7 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1682 PF07946.14 GBG63386.1 - 0.75 8.9 11.4 1.3 8.2 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MDFI PF15316.6 GBG63386.1 - 3 7.9 12.2 6 6.9 1.5 3.4 1 1 1 3 3 3 0 MyoD family inhibitor Glycolytic PF00274.19 GBG63387.1 - 9.7e-160 531.0 0.0 1.1e-159 530.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I PP2C PF00481.21 GBG63391.1 - 4.4e-74 249.4 0.0 5e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GBG63391.1 - 6.7e-07 29.1 0.0 1.6e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GBG63391.1 - 0.00025 21.0 0.1 0.0028 17.6 0.1 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) UDPGP PF01704.18 GBG63393.1 - 1.8e-16 59.8 0.0 2.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase G8 PF10162.9 GBG63393.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 G8 domain Snf7 PF03357.21 GBG63394.1 - 1.1e-47 161.9 8.8 1.3e-47 161.6 8.8 1.1 1 0 0 1 1 1 1 Snf7 MIS13 PF08202.11 GBG63394.1 - 0.025 13.9 3.9 0.032 13.5 3.9 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Phasin_2 PF09361.10 GBG63394.1 - 0.17 12.1 7.4 2.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Phasin protein Spc7 PF08317.11 GBG63394.1 - 0.23 10.3 7.3 0.32 9.8 7.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 GBG63394.1 - 0.81 10.4 9.1 2.5 8.8 1.2 2.4 1 1 1 2 2 2 0 Initiation control protein YabA IFP_35_N PF07334.13 GBG63394.1 - 1.4 9.0 3.8 0.83 9.8 0.4 2.3 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Kelch_1 PF01344.25 GBG63395.1 - 4.6e-21 74.1 12.0 1.1e-10 40.9 0.1 6.2 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GBG63395.1 - 2.4e-16 59.3 1.6 9.1e-07 29.0 0.0 5.1 5 2 1 6 6 6 3 Kelch motif Kelch_4 PF13418.6 GBG63395.1 - 1.4e-10 41.0 4.5 1.1e-05 25.3 0.0 4.4 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GBG63395.1 - 7.8e-07 29.2 7.8 0.00042 20.5 0.3 4.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GBG63395.1 - 9e-05 22.3 5.2 0.028 14.4 0.0 5.1 5 1 0 5 5 5 1 Kelch motif Kelch_5 PF13854.6 GBG63395.1 - 0.048 13.7 1.3 4.2 7.5 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Hira PF07569.11 GBG63395.1 - 0.27 10.9 0.5 23 4.6 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split BPL_LplA_LipB PF03099.19 GBG63396.1 - 5.3e-11 42.5 0.0 9.6e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Auxin_BP PF02041.16 GBG63397.1 - 5.3e-48 162.8 0.1 6.6e-48 162.5 0.1 1.1 1 0 0 1 1 1 1 Auxin binding protein Cupin_2 PF07883.11 GBG63397.1 - 6.8e-11 41.7 0.2 1.9e-10 40.3 0.2 1.8 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 GBG63397.1 - 3.7e-06 26.6 0.0 5.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 GBG63397.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Thioredoxin_10 PF17991.1 GBG63397.1 - 0.12 13.0 0.1 0.35 11.4 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin like C-terminal domain Arm PF00514.23 GBG63399.1 - 3.3e-93 303.2 12.7 2e-12 46.7 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GBG63399.1 - 1.1e-25 89.7 0.7 1.7e-09 38.0 0.0 6.0 4 2 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 GBG63399.1 - 9e-22 77.3 0.0 8.4e-09 35.7 0.0 4.8 2 1 1 5 5 4 4 HEAT repeats IBB PF01749.20 GBG63399.1 - 4.4e-21 75.1 6.2 1e-20 73.9 5.9 1.8 2 0 0 2 2 1 1 Importin beta binding domain Arm_3 PF16186.5 GBG63399.1 - 1e-19 69.8 3.8 1e-19 69.8 3.8 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT PF02985.22 GBG63399.1 - 6.3e-16 57.1 3.8 1.8e-05 24.6 0.0 8.3 9 0 0 9 9 9 2 HEAT repeat Arm_2 PF04826.13 GBG63399.1 - 2e-08 34.0 0.1 0.024 14.1 0.3 4.1 2 1 2 4 4 4 3 Armadillo-like NopRA1 PF16201.5 GBG63399.1 - 1e-06 28.5 0.0 0.61 9.6 0.0 4.3 3 2 1 4 4 4 2 Nucleolar pre-ribosomal-associated protein 1 Adaptin_N PF01602.20 GBG63399.1 - 9.2e-06 24.5 0.0 0.12 10.9 0.0 3.0 1 1 1 2 2 2 2 Adaptin N terminal region Atx10homo_assoc PF09759.9 GBG63399.1 - 9.9e-06 25.5 0.2 0.018 15.0 0.0 2.9 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 GBG63399.1 - 2.6e-05 24.5 0.3 0.86 10.5 0.0 5.8 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 GBG63399.1 - 7.5e-05 22.9 0.8 0.36 11.1 0.0 5.0 5 2 2 7 7 7 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 GBG63399.1 - 8.9e-05 22.6 0.0 7 6.8 0.0 4.4 4 1 0 4 4 4 1 V-ATPase subunit H Mo25 PF08569.11 GBG63399.1 - 0.14 11.4 0.1 0.53 9.6 0.0 1.9 2 1 0 2 2 2 0 Mo25-like GP63 PF17471.2 GBG63400.1 - 0.00058 20.0 4.6 0.97 9.6 0.0 5.1 3 2 1 5 5 5 1 Gene product 63 Beta_helix PF13229.6 GBG63400.1 - 0.078 12.8 5.8 6.7 6.5 4.6 2.4 1 1 1 2 2 2 0 Right handed beta helix region DUF2109 PF09882.9 GBG63400.1 - 2.4 8.2 4.8 2.6e+02 1.7 0.0 4.9 6 1 0 6 6 6 0 Predicted membrane protein (DUF2109) IATP PF04568.12 GBG63401.1 - 4.7e-06 27.0 3.0 4.7e-06 27.0 3.0 1.8 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP CDRT4 PF15213.6 GBG63401.1 - 0.0085 16.7 0.2 0.011 16.4 0.2 1.1 1 0 0 1 1 1 1 CMT1A duplicated region transcript 4 protein DUF1635 PF07795.11 GBG63402.1 - 0.096 12.5 2.2 0.16 11.8 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) FlbD PF06289.11 GBG63402.1 - 0.15 11.7 0.8 0.34 10.5 0.8 1.6 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins RVT_1 PF00078.27 GBG63403.1 - 0.016 14.7 0.1 2.3 7.6 0.0 3.1 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) BTV_NS2 PF04514.12 GBG63403.1 - 0.057 12.2 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 His_Phos_1 PF00300.22 GBG63404.1 - 7.1e-17 61.7 0.0 1.2e-10 41.4 0.0 2.9 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 GBG63405.1 - 1.7e-25 90.2 0.0 4.5e-24 85.5 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RT_RNaseH PF17917.1 GBG63406.1 - 1.2e-27 96.2 0.0 2.4e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63406.1 - 2e-21 75.9 0.0 4.4e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2249 PF10006.9 GBG63406.1 - 0.046 13.6 0.0 0.88 9.5 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) SDA1 PF05285.12 GBG63406.1 - 0.084 12.3 21.4 0.11 11.9 21.4 1.1 1 0 0 1 1 1 0 SDA1 DUF2201_N PF13203.6 GBG63406.1 - 0.25 10.9 4.1 0.39 10.3 4.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.12 GBG63406.1 - 0.53 8.4 20.0 0.67 8.1 20.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG63406.1 - 1.1 7.4 14.6 1.5 7.1 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG63406.1 - 3.6 6.8 21.3 4.8 6.4 21.3 1.1 1 0 0 1 1 1 0 BUD22 RETICULATA-like PF11891.8 GBG63408.1 - 2.8e-53 180.4 0.0 5.4e-53 179.4 0.0 1.5 1 0 0 1 1 1 1 Protein RETICULATA-related Cofac_haem_bdg PF04187.13 GBG63408.1 - 3.5e-33 115.4 0.0 6.2e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN PsbQ PF05757.11 GBG63408.1 - 0.035 13.9 0.6 0.035 13.9 0.6 2.5 1 1 1 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) RETICULATA-like PF11891.8 GBG63409.1 - 1.6e-54 184.4 0.0 3.1e-54 183.5 0.0 1.5 1 0 0 1 1 1 1 Protein RETICULATA-related Cofac_haem_bdg PF04187.13 GBG63409.1 - 3.5e-33 115.4 0.0 6.2e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN PsbQ PF05757.11 GBG63409.1 - 0.035 13.9 0.6 0.035 13.9 0.6 2.7 2 1 1 3 3 3 0 Oxygen evolving enhancer protein 3 (PsbQ) RVT_1 PF00078.27 GBG63410.1 - 2e-21 76.6 0.0 3.6e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) N6_N4_Mtase PF01555.18 GBG63410.1 - 4.9e-08 33.0 0.0 0.0028 17.4 0.0 2.8 2 1 0 2 2 2 2 DNA methylase Exo_endo_phos PF03372.23 GBG63410.1 - 0.00026 20.6 0.0 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_transf_34 PF05637.12 GBG63411.1 - 1.2e-27 97.1 0.0 2.7e-27 96.0 0.0 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 GBG63411.1 - 2.5e-06 27.2 0.0 0.0086 15.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF273 Selenoprotein_S PF06936.11 GBG63413.1 - 0.0091 15.8 4.3 0.0091 15.8 4.3 3.2 1 1 2 3 3 3 1 Selenoprotein S (SelS) HrcA_DNA-bdg PF03444.15 GBG63413.1 - 0.023 14.3 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Baculo_p24 PF05073.12 GBG63413.1 - 0.025 14.4 1.8 0.035 13.9 0.1 2.0 2 1 0 2 2 2 0 Baculovirus P24 capsid protein HEPN_Swt1 PF18731.1 GBG63413.1 - 2.3 8.6 8.4 2.6 8.4 5.3 2.4 2 0 0 2 2 2 0 Swt1-like HEPN Ribosomal_S5 PF00333.20 GBG63413.1 - 8.1 6.5 7.2 0.4 10.7 0.3 2.2 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Acetyltransf_1 PF00583.25 GBG63414.1 - 4.9e-12 46.1 0.0 8.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GBG63414.1 - 1.5e-11 44.4 0.0 2.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GBG63414.1 - 1e-09 38.7 0.0 1.7e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GBG63414.1 - 0.0027 17.8 0.0 0.0069 16.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GBG63414.1 - 0.0055 16.2 0.0 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 GBG63414.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Cadherin_C PF01049.17 GBG63414.1 - 0.034 14.5 0.2 0.068 13.5 0.2 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic region Acetyltransf_CG PF14542.6 GBG63414.1 - 0.038 14.1 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CDC45 PF02724.14 GBG63415.1 - 0.71 8.1 9.4 1.2 7.3 9.4 1.4 1 0 0 1 1 1 0 CDC45-like protein CLP_protease PF00574.23 GBG63416.1 - 4.4e-19 69.1 0.0 3.5e-10 40.1 0.0 2.3 1 1 1 2 2 2 2 Clp protease FoP_duplication PF13865.6 GBG63416.1 - 6.9 7.3 13.3 12 6.5 13.3 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 CNDH2_C PF16858.5 GBG63417.1 - 6.4e-43 147.7 3.9 1.4e-42 146.6 0.2 2.9 2 1 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 GBG63417.1 - 2.6e-31 108.1 0.5 1.1e-30 106.1 0.0 2.2 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Cnd2 PF05786.14 GBG63417.1 - 0.064 11.9 2.3 0.1 11.2 0.0 2.3 2 0 0 2 2 2 0 Condensin complex subunit 2 Pkinase_Tyr PF07714.17 GBG63418.1 - 9.6e-44 149.6 0.0 1.4e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG63418.1 - 1.3e-39 136.2 0.0 1.9e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Malectin_like PF12819.7 GBG63418.1 - 2.8e-29 102.4 0.0 3.6e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Malectin-like domain Malectin PF11721.8 GBG63418.1 - 2.6e-22 79.7 0.0 2.3e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Malectin domain LRRNT_2 PF08263.12 GBG63418.1 - 1.2e-05 25.5 0.2 3.9e-05 23.9 0.2 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 GBG63418.1 - 0.0074 16.0 0.9 0.0074 16.0 0.9 2.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 GBG63418.1 - 0.098 13.1 2.8 10 6.7 0.7 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) RSB_motif PF16294.5 GBG63419.1 - 3.7 7.9 16.6 4.6 7.6 16.6 1.1 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif zf-CCHC PF00098.23 GBG63420.1 - 0.021 14.9 1.9 0.038 14.1 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG63421.1 - 1.2e-18 67.4 0.0 2.6e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63421.1 - 1.1e-10 41.4 0.0 2.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG63421.1 - 0.0094 16.5 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63421.1 - 0.017 15.7 0.0 0.049 14.3 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease SDA1 PF05285.12 GBG63421.1 - 0.14 11.5 14.9 0.26 10.7 14.9 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG63421.1 - 0.17 10.1 15.2 0.27 9.4 15.2 1.2 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG63421.1 - 2.4 7.7 8.3 3.9 7.0 8.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 GBG63421.1 - 3 6.0 12.0 4.4 5.5 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein AMP-binding PF00501.28 GBG63422.1 - 6.5e-92 308.3 0.0 8.6e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RVT_1 PF00078.27 GBG63423.1 - 1.3e-18 67.3 0.0 1.5e-15 57.4 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DRY_EERY PF09750.9 GBG63423.1 - 3.5e-11 43.5 0.1 3.5e-11 43.5 0.1 4.0 4 0 0 4 4 4 1 Alternative splicing regulator RVT_1 PF00078.27 GBG63424.1 - 1.3e-18 67.4 0.0 1.4e-15 57.4 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DRY_EERY PF09750.9 GBG63424.1 - 3.5e-11 43.5 0.1 3.5e-11 43.5 0.1 4.0 4 0 0 4 4 4 1 Alternative splicing regulator RVT_1 PF00078.27 GBG63425.1 - 1.3e-18 67.3 0.0 1.4e-15 57.4 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DRY_EERY PF09750.9 GBG63425.1 - 3.5e-11 43.5 0.1 3.5e-11 43.5 0.1 4.0 4 0 0 4 4 4 1 Alternative splicing regulator Nucleotid_trans PF03407.16 GBG63427.1 - 1.9e-06 28.0 0.0 0.00099 19.1 0.0 3.0 3 0 0 3 3 3 2 Nucleotide-diphospho-sugar transferase Nop14 PF04147.12 GBG63428.1 - 0.091 11.0 26.8 0.11 10.6 26.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG63428.1 - 0.14 11.5 24.1 0.21 11.0 24.1 1.2 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 GBG63428.1 - 0.45 9.8 21.5 0.72 9.2 21.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GBG63428.1 - 0.57 8.4 21.3 0.73 8.0 21.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG63428.1 - 1.7 6.6 32.2 2.3 6.2 32.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 GBG63428.1 - 2.9 8.3 7.7 5.9 7.3 7.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2201_N PF13203.6 GBG63428.1 - 5 6.6 7.4 8.5 5.9 7.4 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain BUD22 PF09073.10 GBG63428.1 - 5.9 6.1 24.6 8.7 5.6 24.6 1.3 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 GBG63428.1 - 6.6 5.8 13.5 10 5.3 13.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4045 PF13254.6 GBG63429.1 - 0.039 13.6 11.8 0.052 13.2 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Retrotrans_gag PF03732.17 GBG63429.1 - 0.091 13.0 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein RP-C_C PF11800.8 GBG63429.1 - 0.5 10.4 5.1 0.93 9.6 5.1 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.17 GBG63429.1 - 0.52 9.0 8.1 0.66 8.7 8.1 1.1 1 0 0 1 1 1 0 Presenilin RT_RNaseH PF17917.1 GBG63430.1 - 2.9e-23 82.1 0.0 5.1e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63430.1 - 4e-21 74.9 0.0 6.7e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63430.1 - 2.9e-17 62.5 1.9 7.3e-17 61.2 1.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63430.1 - 3.3e-16 59.5 0.0 9.8e-16 57.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG63430.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 Nif11 PF07862.11 GBG63430.1 - 0.15 12.4 0.0 0.57 10.5 0.0 2.0 1 0 0 1 1 1 0 Nif11 domain SUZ PF12752.7 GBG63432.1 - 10 7.0 14.3 1.1 10.1 1.5 3.9 2 2 0 2 2 2 0 SUZ domain DUF3089 PF11288.8 GBG63434.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) RVT_1 PF00078.27 GBG63435.1 - 2.6e-32 112.1 0.0 3.9e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) K_channel_TID PF07941.11 GBG63436.1 - 0.37 11.3 9.6 0.67 10.4 9.6 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain F-box-like PF12937.7 GBG63437.1 - 1.6e-05 24.7 0.0 4.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG63437.1 - 0.051 13.5 0.3 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 GBG63438.1 - 7.6e-05 22.5 0.2 0.00021 21.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like Hum_adeno_E3A PF05393.11 GBG63438.1 - 0.061 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein F-box PF00646.33 GBG63438.1 - 4.1 7.4 6.1 2.8 7.9 0.3 3.1 3 1 0 3 3 3 0 F-box domain RT_RNaseH_2 PF17919.1 GBG63439.1 - 1.2e-28 99.1 0.0 2e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63439.1 - 8.9e-26 90.2 0.0 1.4e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG63439.1 - 1.9 7.8 14.4 2.6 7.4 14.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG63439.1 - 2.4 7.4 18.8 3.5 6.9 18.8 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG63439.1 - 2.8 6.1 17.1 3.7 5.6 17.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG63439.1 - 7.5 4.5 20.8 11 4.0 20.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi HSP70 PF00012.20 GBG63440.1 - 2.8e-127 425.4 14.6 1.4e-57 195.2 0.0 4.0 2 1 2 4 4 3 3 Hsp70 protein MreB_Mbl PF06723.13 GBG63440.1 - 2.9e-10 39.5 3.0 0.0005 19.0 0.2 4.2 4 1 0 4 4 4 3 MreB/Mbl protein FGGY_C PF02782.16 GBG63440.1 - 1.4e-05 24.9 0.0 3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Nop14 PF04147.12 GBG63440.1 - 0.069 11.4 10.1 0.097 10.9 10.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG63440.1 - 0.2 11.0 14.6 0.31 10.4 14.6 1.2 1 0 0 1 1 1 0 SDA1 TEX19 PF15553.6 GBG63440.1 - 0.24 11.4 4.5 0.53 10.2 4.5 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 CPSF100_C PF13299.6 GBG63440.1 - 0.26 11.5 5.6 0.52 10.5 5.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 GBG63440.1 - 0.29 9.4 10.2 0.46 8.7 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 GBG63440.1 - 0.3 10.0 1.6 0.47 9.4 1.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hydin_ADK PF17213.3 GBG63440.1 - 0.31 11.3 2.1 0.66 10.2 2.1 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RNA_pol_Rpc4 PF05132.14 GBG63440.1 - 0.35 11.3 5.4 0.71 10.3 5.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sin_N PF04801.13 GBG63440.1 - 0.47 9.6 6.5 0.72 9.0 6.5 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region RR_TM4-6 PF06459.12 GBG63440.1 - 0.9 9.3 12.2 1.4 8.7 12.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FtsA PF14450.6 GBG63440.1 - 0.91 10.0 3.5 63 4.1 0.3 4.0 4 0 0 4 4 4 0 Cell division protein FtsA TRAP_alpha PF03896.16 GBG63440.1 - 1 8.5 4.3 1.5 7.9 4.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TMEM119 PF15724.5 GBG63440.1 - 1.6 8.7 9.5 3.4 7.7 9.5 1.4 1 0 0 1 1 1 0 TMEM119 family Ribosomal_60s PF00428.19 GBG63440.1 - 1.7 9.3 10.5 2.1 9.0 3.2 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Tim54 PF11711.8 GBG63440.1 - 3.2 6.4 9.6 5.2 5.7 9.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.10 GBG63440.1 - 4.5 7.6 16.3 7.3 6.9 16.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.6 GBG63440.1 - 6.6 6.4 7.8 1 9.0 3.5 1.9 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.17 GBG63440.1 - 7 5.3 9.9 11 4.7 9.9 1.1 1 0 0 1 1 1 0 Presenilin PRP1_N PF06424.12 GBG63442.1 - 0.54 10.6 13.8 0.61 10.5 13.8 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal RNA_pol_Rpc4 PF05132.14 GBG63442.1 - 7.7 6.9 11.3 8.5 6.8 11.3 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 GBG63442.1 - 8.4 5.8 12.7 8.9 5.7 12.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF659 PF04937.15 GBG63443.1 - 1.4e-25 89.9 0.0 2.4e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG63444.1 - 2.9e-19 68.9 0.1 6.6e-19 67.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG63444.1 - 5.8e-16 58.7 0.1 1.3e-15 57.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63444.1 - 2.5e-09 37.3 0.0 1e-08 35.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG63444.1 - 2.3e-08 34.0 0.0 5.9e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG63444.1 - 7.9e-06 25.7 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63444.1 - 8.8e-05 23.1 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG63444.1 - 0.00012 21.6 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG63444.1 - 0.0051 17.0 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG63444.1 - 0.0073 16.8 0.0 0.025 15.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease LysR_substrate PF03466.20 GBG63444.1 - 0.061 12.7 0.1 0.17 11.2 0.1 1.7 1 0 0 1 1 1 0 LysR substrate binding domain RT_RNaseH_2 PF17919.1 GBG63445.1 - 7.3e-30 103.0 0.0 1.9e-29 101.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63445.1 - 1.5e-27 95.9 0.1 3.7e-27 94.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63445.1 - 1.5e-18 67.2 0.0 3.1e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63445.1 - 1.4e-07 31.7 0.0 5.9e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain AAA PF00004.29 GBG63445.1 - 1e-05 25.9 0.0 2.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Retrotrans_gag PF03732.17 GBG63445.1 - 0.0018 18.5 0.0 0.099 12.9 0.0 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein Peptidase_C13 PF01650.18 GBG63446.1 - 1.2e-104 349.3 0.0 1.8e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 GBG63446.1 - 0.0028 17.7 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain ALMT PF11744.8 GBG63447.1 - 8 5.2 7.4 15 4.3 7.4 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter N6_N4_Mtase PF01555.18 GBG63448.1 - 3.1e-07 30.4 0.0 6.4e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 DNA methylase DUF4539 PF15072.6 GBG63449.1 - 9.4 6.4 11.3 2.6 8.2 1.3 3.0 1 1 2 4 4 4 0 Domain of unknown function (DUF4539) rve PF00665.26 GBG63450.1 - 1.1e-12 48.2 0.0 2.3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG63450.1 - 1.3e-05 25.7 0.2 3.8e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63450.1 - 4.3e-05 24.1 0.0 0.0001 22.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG63450.1 - 0.0093 16.0 1.1 0.0093 16.0 1.1 2.4 2 0 0 2 2 2 1 Zinc knuckle RVP PF00077.20 GBG63450.1 - 0.085 13.2 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_C2 PF00648.21 GBG63451.1 - 1.1e-13 50.9 0.0 1.9e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 GBG63452.1 - 1e-13 51.0 0.0 1.9e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DUF659 PF04937.15 GBG63453.1 - 5.7e-37 126.9 0.0 1e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG63453.1 - 0.0025 17.8 1.0 0.0068 16.4 1.0 1.8 1 0 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 GBG63453.1 - 0.014 15.1 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region zf-C2H2_4 PF13894.6 GBG63453.1 - 0.2 12.6 0.6 0.66 11.0 0.6 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Peptidase_C2 PF00648.21 GBG63454.1 - 6.9e-117 389.7 0.0 5e-47 160.4 0.0 3.2 3 0 0 3 3 3 3 Calpain family cysteine protease Peptidase_C2 PF00648.21 GBG63455.1 - 5e-62 209.6 0.0 7.5e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 GBG63456.1 - 1.6e-41 142.3 0.0 2.5e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Cons_hypoth95 PF03602.15 GBG63457.1 - 0.00039 20.1 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 GBG63457.1 - 0.0088 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 GBG63457.1 - 0.045 13.5 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein tRNA_U5-meth_tr PF05958.11 GBG63457.1 - 0.097 11.6 0.2 6.1 5.7 0.0 2.4 3 0 0 3 3 3 0 tRNA (Uracil-5-)-methyltransferase DUF1442 PF07279.11 GBG63457.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) PPP4R2 PF09184.11 GBG63457.1 - 0.39 10.3 8.5 0.68 9.5 8.5 1.4 1 0 0 1 1 1 0 PPP4R2 PLA2G12 PF06951.11 GBG63457.1 - 1 9.3 8.3 0.22 11.4 4.6 1.7 2 0 0 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) SGT1 PF07093.11 GBG63457.1 - 3.1 6.1 6.5 4.2 5.7 6.5 1.1 1 0 0 1 1 1 0 SGT1 protein DNA_pol_phi PF04931.13 GBG63457.1 - 6.9 4.6 23.6 10 4.1 23.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cons_hypoth95 PF03602.15 GBG63458.1 - 0.00037 20.2 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 GBG63458.1 - 0.0089 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 GBG63458.1 - 0.046 13.5 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DUF1442 PF07279.11 GBG63458.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) tRNA_U5-meth_tr PF05958.11 GBG63458.1 - 0.14 11.1 0.1 6.3 5.7 0.0 2.1 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase PPP4R2 PF09184.11 GBG63458.1 - 0.41 10.2 8.5 0.7 9.4 8.5 1.4 1 0 0 1 1 1 0 PPP4R2 PLA2G12 PF06951.11 GBG63458.1 - 1.1 9.2 8.3 0.22 11.4 4.6 1.7 2 0 0 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) SGT1 PF07093.11 GBG63458.1 - 3.2 6.1 6.5 4.3 5.7 6.5 1.1 1 0 0 1 1 1 0 SGT1 protein DNA_pol_phi PF04931.13 GBG63458.1 - 6.5 4.7 23.6 10 4.0 23.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi FKBP_C PF00254.28 GBG63459.1 - 1.2e-17 64.0 0.0 2e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RVT_1 PF00078.27 GBG63460.1 - 1.9e-30 106.0 0.1 3.6e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nas2_N PF18265.1 GBG63460.1 - 1.1e-20 73.3 0.0 2.4e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Nas2 N_terminal domain Asp_protease_2 PF13650.6 GBG63460.1 - 6.8e-07 29.9 0.0 2.6e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63460.1 - 1.5e-06 28.7 0.0 4.2e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63460.1 - 4.7e-06 26.4 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63460.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG63460.1 - 0.025 14.6 0.0 0.071 13.2 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Nucleoside_tran PF01733.18 GBG63461.1 - 6.3e-52 176.9 11.2 1.9e-32 112.9 5.0 2.2 2 0 0 2 2 2 2 Nucleoside transporter RseC_MucC PF04246.12 GBG63461.1 - 0.98 9.4 3.7 0.77 9.7 0.7 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TRAPP PF04051.16 GBG63462.1 - 2.5e-40 137.5 0.0 2.6e-39 134.3 0.0 1.9 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component PLAC8 PF04749.17 GBG63463.1 - 4.3e-18 66.1 7.8 7.6e-18 65.4 7.8 1.4 1 0 0 1 1 1 1 PLAC8 family Gsf2 PF11055.8 GBG63463.1 - 0.1 11.4 1.0 0.15 10.8 1.0 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 Mt_ATP-synt_D PF05873.12 GBG63463.1 - 0.51 10.2 3.2 1.1 9.1 3.2 1.5 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Iso_dh PF00180.20 GBG63464.1 - 1.3e-104 350.1 0.0 1.5e-104 349.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RT_RNaseH_2 PF17919.1 GBG63465.1 - 2.8e-64 213.4 0.2 4.3e-34 116.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63465.1 - 5.3e-60 200.2 0.2 3.2e-32 110.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63465.1 - 1.2e-27 96.9 0.2 3.2e-17 62.8 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63465.1 - 5e-15 55.7 0.0 1.1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG63465.1 - 4.4e-07 29.9 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG63465.1 - 2.5e-05 24.4 0.0 7.3e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG63465.1 - 0.24 11.6 0.3 0.65 10.2 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Mucin PF01456.17 GBG63466.1 - 2.3 8.2 6.1 3.8 7.5 6.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RVT_1 PF00078.27 GBG63467.1 - 9e-37 126.7 0.0 1.4e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63467.1 - 6e-31 106.4 0.0 1.7e-30 105.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63467.1 - 2.4e-28 98.5 0.0 6.4e-28 97.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63467.1 - 3.3e-10 39.9 0.0 7.9e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG63468.1 - 0.00096 19.4 1.2 0.052 13.8 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein Phage_lysozyme PF00959.19 GBG63468.1 - 0.094 13.2 0.1 0.58 10.6 0.0 2.4 2 1 0 2 2 2 0 Phage lysozyme DUF2868 PF11067.8 GBG63469.1 - 0.29 10.6 2.8 0.35 10.3 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) RT_RNaseH_2 PF17919.1 GBG63470.1 - 3.9e-57 190.5 0.0 1.9e-27 95.2 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63470.1 - 1.3e-48 163.6 0.0 1.2e-25 89.8 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63470.1 - 4.6e-18 65.1 2.3 5.5e-18 64.8 0.7 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63470.1 - 5.6e-16 58.7 0.1 1.5e-12 47.5 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63470.1 - 1.9e-15 57.1 0.0 6.3e-15 55.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63470.1 - 6.2e-05 23.1 0.1 0.00022 21.3 0.1 2.1 2 0 0 2 2 2 1 H2C2 zinc finger DUF4392 PF14336.6 GBG63470.1 - 0.078 12.4 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) RVT_2 PF07727.14 GBG63470.1 - 0.12 11.9 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_16 PF18348.1 GBG63470.1 - 0.15 11.9 0.1 23 4.9 0.0 3.0 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain RVT_1 PF00078.27 GBG63471.1 - 1e-18 67.7 0.1 2.4e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63471.1 - 6.6e-08 32.8 0.0 1.7e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG63471.1 - 0.0002 21.2 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3499 PF12005.8 GBG63471.1 - 0.91 10.1 9.0 0.29 11.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) TSP_1 PF00090.19 GBG63472.1 - 1.2e-19 70.3 44.8 1.8e-08 34.5 5.2 4.9 4 0 0 4 4 4 4 Thrombospondin type 1 domain UPF0061 PF02696.14 GBG63473.1 - 1.2e-131 439.7 0.0 1.6e-131 439.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family RVT_1 PF00078.27 GBG63473.1 - 2.7e-39 135.0 0.0 5.8e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cupin_2 PF07883.11 GBG63475.1 - 1.2e-05 24.9 0.0 1.5e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 GBG63475.1 - 0.0015 18.4 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Serinc PF03348.15 GBG63476.1 - 1e-119 400.3 2.4 1.2e-119 400.1 2.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF1746 PF08508.10 GBG63476.1 - 0.0058 17.0 0.1 0.03 14.7 0.0 2.3 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1746) Lysis_col PF02402.16 GBG63476.1 - 1.8 8.3 7.5 4.9 6.9 0.9 3.4 3 0 0 3 3 3 0 Lysis protein Med4 PF10018.9 GBG63477.1 - 3.5e-08 33.4 3.5 9.7e-08 31.9 3.5 1.7 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Collagen PF01391.18 GBG63477.1 - 0.011 15.5 2.9 0.011 15.5 2.9 1.8 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Sigma70_ner PF04546.13 GBG63477.1 - 0.015 15.2 2.8 0.015 15.2 2.8 1.8 2 0 0 2 2 1 0 Sigma-70, non-essential region SDA1 PF05285.12 GBG63477.1 - 0.016 14.7 1.9 0.028 13.9 1.9 1.4 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 GBG63477.1 - 0.24 11.7 8.0 0.69 10.2 8.0 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CobT PF06213.12 GBG63477.1 - 1.3 8.4 8.8 3 7.2 8.8 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GBG63477.1 - 2.8 6.1 6.2 4.1 5.6 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG63477.1 - 7.3 4.7 11.5 13 3.8 11.5 1.3 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.12 GBG63477.1 - 7.6 5.4 10.4 12 4.7 10.4 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Paf1 PF03985.13 GBG63477.1 - 8 5.3 10.5 12 4.7 10.5 1.1 1 0 0 1 1 1 0 Paf1 RRN3 PF05327.11 GBG63477.1 - 8.7 4.8 5.3 95 1.3 6.8 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 PCI PF01399.27 GBG63478.1 - 4.1e-11 43.3 0.1 1.1e-10 41.9 0.1 1.8 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 GBG63478.1 - 2.6e-10 39.8 0.7 4.6e-10 39.0 0.7 1.4 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix XRCC4 PF06632.12 GBG63479.1 - 0.25 10.2 3.7 0.39 9.5 3.7 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RT_RNaseH_2 PF17919.1 GBG63480.1 - 1.7e-25 88.9 0.0 3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63480.1 - 4.7e-23 81.5 0.0 9.1e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63480.1 - 5.5e-21 75.1 0.1 9.1e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG63480.1 - 1 7.5 4.4 1.4 7.1 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family S-AdoMet_synt_C PF02773.16 GBG63481.1 - 8.1e-65 217.0 0.8 1.5e-64 216.1 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GBG63481.1 - 9.4e-48 161.4 0.0 1.7e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG63481.1 - 1.5e-43 147.5 0.2 3.1e-43 146.5 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Chitin_bind_4 PF00379.23 GBG63481.1 - 0.0026 18.2 0.0 0.0059 17.1 0.0 1.7 1 0 0 1 1 1 1 Insect cuticle protein Pkinase PF00069.25 GBG63482.1 - 2.2e-41 142.0 0.0 6.2e-40 137.2 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63482.1 - 1.2e-18 67.3 0.0 3.9e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Nop14 PF04147.12 GBG63482.1 - 0.24 9.6 11.4 0.32 9.2 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG63482.1 - 0.37 10.1 11.1 0.44 9.8 10.1 1.6 2 0 0 2 2 2 0 NOA36 protein SDA1 PF05285.12 GBG63482.1 - 1.6 8.0 13.6 0.091 12.2 8.5 1.4 2 0 0 2 2 2 0 SDA1 RNA_pol_3_Rpc31 PF11705.8 GBG63482.1 - 3.7 7.8 14.5 6.2 7.0 14.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 GBG63482.1 - 4.1 6.9 12.0 6.5 6.2 12.0 1.3 1 0 0 1 1 1 0 PPP4R2 TRAP_alpha PF03896.16 GBG63482.1 - 4.1 6.5 9.2 7 5.8 9.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Myc_N PF01056.18 GBG63482.1 - 4.7 7.0 8.0 8.6 6.2 8.0 1.4 1 0 0 1 1 1 0 Myc amino-terminal region RPN2_C PF18004.1 GBG63482.1 - 6.1 6.8 7.4 16 5.4 7.4 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Astro_capsid_p PF12226.8 GBG63482.1 - 9.6 5.2 10.8 15 4.6 10.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF3246 PF11596.8 GBG63483.1 - 0.47 9.8 6.1 0.91 8.9 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 GBG63483.1 - 2.9 7.6 8.5 5.6 6.6 8.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Steroid_dh PF02544.16 GBG63484.1 - 4.9e-13 49.3 0.2 4.1e-11 43.1 0.1 2.5 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase Peptidase_M1_N PF17900.1 GBG63487.1 - 1.3e-07 32.0 0.0 1.5e-07 31.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Toprim_4 PF13662.6 GBG63488.1 - 2.6e-18 66.3 0.0 5.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DnaB_C PF03796.15 GBG63488.1 - 1.8e-09 37.3 0.0 2.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_2 PF13155.6 GBG63488.1 - 7.6e-08 32.7 0.0 1.9e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Toprim-like AAA_25 PF13481.6 GBG63488.1 - 8e-07 28.8 0.0 3.9e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain Toprim PF01751.22 GBG63488.1 - 4.6e-06 26.8 0.0 3.9e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Toprim domain Toprim_3 PF13362.6 GBG63488.1 - 0.00039 20.7 0.7 0.0059 16.9 0.1 2.3 2 0 0 2 2 2 1 Toprim domain FtsK_SpoIIIE PF01580.18 GBG63488.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 GBG63488.1 - 0.12 12.1 0.7 0.24 11.2 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain RR_TM4-6 PF06459.12 GBG63488.1 - 6.1 6.6 7.1 9.1 6.0 7.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NOA36 PF06524.12 GBG63488.1 - 8 5.7 11.3 18 4.5 11.3 1.5 1 0 0 1 1 1 0 NOA36 protein CGI-121 PF08617.10 GBG63489.1 - 1e-30 107.0 0.1 1.2e-30 106.8 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF2605 PF10792.9 GBG63489.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) CLAMP PF14769.6 GBG63490.1 - 2.2e-27 95.4 2.9 3.5e-27 94.8 2.9 1.3 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 RPAP3_C PF13877.6 GBG63490.1 - 0.013 16.1 1.1 0.027 15.0 1.1 1.5 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 DUF4364 PF14277.6 GBG63490.1 - 0.089 12.5 1.2 0.21 11.4 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Thymopoietin PF08198.11 GBG63490.1 - 0.12 12.0 0.1 9.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Thymopoietin protein PROCN PF08083.11 GBG63490.1 - 0.17 10.6 3.6 0.34 9.6 0.1 2.0 1 1 1 2 2 2 0 PROCN (NUC071) domain DUF1676 PF07898.13 GBG63490.1 - 2.1 8.3 4.9 5.4 7.0 4.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) AAA_23 PF13476.6 GBG63490.1 - 2.9 8.3 9.5 6.9 7.1 9.5 1.7 1 1 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.19 GBG63492.1 - 2.5e-12 46.7 2.3 6.1e-10 38.9 0.4 2.8 2 1 0 2 2 2 2 FAD binding domain RT_RNaseH_2 PF17919.1 GBG63494.1 - 1.1e-22 79.9 0.0 2.2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63494.1 - 8.7e-21 74.2 0.0 1.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63494.1 - 5.6e-17 61.6 2.5 1.5e-16 60.2 0.3 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63494.1 - 1.4e-09 37.8 0.1 3e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63494.1 - 7.6e-07 29.3 0.0 2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63494.1 - 0.0032 17.6 0.1 0.0077 16.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG63495.1 - 0.00028 21.2 2.8 0.00028 21.2 2.8 3.0 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG63496.1 - 1.1e-28 99.9 0.0 1.7e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63496.1 - 1.6e-12 47.5 0.0 2.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG63496.1 - 0.00029 20.6 0.6 0.0071 16.0 0.0 3.0 3 1 0 3 3 3 1 Transposase DDE domain Protocadherin PF08374.11 GBG63497.1 - 0.46 10.4 3.8 0.81 9.6 3.8 1.3 1 0 0 1 1 1 0 Protocadherin Ribosomal_L37 PF08561.10 GBG63497.1 - 1.8 9.1 9.8 4.4 7.8 9.8 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 TFIIA PF03153.13 GBG63497.1 - 3.5 7.5 26.0 0.92 9.4 17.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 GBG63497.1 - 7.7 6.5 18.8 27 4.7 18.8 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Osteopontin PF00865.18 GBG63497.1 - 8.2 5.8 34.7 0.28 10.6 26.8 2.4 2 0 0 2 2 2 0 Osteopontin Cwf_Cwc_15 PF04889.12 GBG63500.1 - 0.15 11.8 3.4 0.24 11.1 3.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAP_N PF01213.19 GBG63500.1 - 0.15 11.5 7.6 0.22 11.0 7.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CENP-B_dimeris PF09026.10 GBG63500.1 - 0.34 11.3 7.2 2 8.9 7.8 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 GBG63500.1 - 0.42 9.9 3.7 0.65 9.3 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein PRIMA1 PF16101.5 GBG63500.1 - 3.3 7.8 9.5 6.7 6.8 9.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RskA PF10099.9 GBG63500.1 - 4.8 7.4 13.8 14 5.9 13.8 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DNA_pol_phi PF04931.13 GBG63500.1 - 6.4 4.7 6.4 8.8 4.3 6.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Apolipoprotein PF01442.18 GBG63502.1 - 0.00025 21.0 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain US22 PF02393.16 GBG63502.1 - 0.015 15.6 0.4 0.035 14.4 0.4 1.6 1 0 0 1 1 1 0 US22 like Flg_hook PF02120.16 GBG63502.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK NHL PF01436.21 GBG63502.1 - 0.35 11.0 3.4 0.49 10.5 0.5 2.8 1 1 1 2 2 2 0 NHL repeat RT_RNaseH_2 PF17919.1 GBG63503.1 - 1e-27 96.1 0.0 2.8e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63503.1 - 4.5e-25 88.0 0.0 1e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63503.1 - 4.5e-17 61.9 0.7 1.3e-16 60.4 0.7 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63503.1 - 1.4e-09 37.8 1.0 1.9e-05 24.3 0.2 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG63503.1 - 7.6e-08 32.9 0.0 2.1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63503.1 - 3.9e-06 27.3 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG63503.1 - 0.00088 19.1 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63503.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG63503.1 - 0.016 15.4 0.1 0.099 12.8 0.1 2.4 1 1 1 2 2 2 0 Integrase core domain Retrotrans_gag PF03732.17 GBG63503.1 - 0.045 14.0 0.1 0.045 14.0 0.1 4.3 4 0 0 4 4 4 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG63503.1 - 0.11 12.7 0.1 0.3 11.4 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG63503.1 - 0.73 9.4 8.1 2.2 7.9 8.1 1.8 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase V_ATPase_I PF01496.19 GBG63503.1 - 1.7 6.4 4.4 2.9 5.7 4.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.9 GBG63503.1 - 2.6 8.4 11.3 0.87 9.9 5.9 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 GBG63503.1 - 2.8 6.4 7.1 4.6 5.7 7.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Laminin_II PF06009.12 GBG63503.1 - 3.8 7.5 12.1 31 4.6 0.2 3.5 2 1 0 2 2 2 0 Laminin Domain II Apolipoprotein PF01442.18 GBG63506.1 - 9.7e-11 41.9 0.4 1.6e-10 41.2 0.4 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain NHL PF01436.21 GBG63506.1 - 0.046 13.8 1.0 0.38 10.9 1.0 2.8 1 0 0 1 1 1 0 NHL repeat Flg_hook PF02120.16 GBG63506.1 - 0.18 11.7 0.2 1.1 9.2 0.1 2.3 1 1 1 2 2 2 0 Flagellar hook-length control protein FliK DUF1640 PF07798.11 GBG63506.1 - 0.2 11.7 0.0 0.82 9.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Bactofilin PF04519.13 GBG63506.1 - 0.2 12.0 8.0 2.7 8.3 3.7 3.3 2 1 1 3 3 3 0 Polymer-forming cytoskeletal RVP_2 PF08284.11 GBG63507.1 - 3.2e-05 23.7 0.0 7.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG63507.1 - 0.00018 21.4 1.5 0.00021 21.2 0.1 1.9 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG63507.1 - 0.0073 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63507.1 - 0.029 14.9 0.0 0.091 13.3 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG63507.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG63509.1 - 0.042 14.1 0.1 0.65 10.3 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein DivIC PF04977.15 GBG63509.1 - 0.06 13.1 0.3 0.06 13.1 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator HALZ PF02183.18 GBG63509.1 - 0.07 13.4 0.2 0.2 11.9 0.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 GBG63509.1 - 0.47 10.9 1.8 0.63 10.5 0.3 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 GBG63509.1 - 2.4 8.3 7.3 0.2 11.8 0.6 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Arm PF00514.23 GBG63510.1 - 0.11 12.6 0.8 7.5 6.8 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat gag-asp_proteas PF13975.6 GBG63511.1 - 1.6e-07 31.8 0.1 3e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63511.1 - 4.6e-05 24.0 0.0 0.0002 21.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG63511.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63511.1 - 0.003 17.4 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DUF659 PF04937.15 GBG63513.1 - 1.3e-09 38.1 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63513.1 - 0.022 14.6 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Vasculin PF15337.6 GBG63514.1 - 0.053 14.3 0.1 2.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 RVT_1 PF00078.27 GBG63515.1 - 1.3e-28 100.0 0.0 3e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63515.1 - 6.2e-13 48.6 0.0 1.7e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63515.1 - 0.00041 20.6 0.0 0.0014 18.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG63515.1 - 0.011 16.0 4.8 0.054 13.8 0.0 4.0 4 0 0 4 4 4 0 Retrotransposon gag protein DUF4407 PF14362.6 GBG63515.1 - 4.9 6.4 10.7 16 4.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RT_RNaseH_2 PF17919.1 GBG63516.1 - 4.4e-24 84.4 0.0 1.1e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63516.1 - 7.1e-22 77.7 0.0 1.8e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG63516.1 - 0.00051 20.6 0.0 0.0014 19.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG63516.1 - 0.021 15.1 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63516.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG63516.1 - 0.066 13.5 0.3 0.19 12.0 0.3 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG63516.1 - 0.11 13.2 0.0 0.32 11.7 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG63517.1 - 1.6e-24 85.8 0.0 2.6e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63517.1 - 2.6e-22 79.1 0.0 4.5e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63518.1 - 8.5e-23 80.6 0.0 1.7e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63518.1 - 9e-22 77.0 0.0 2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63518.1 - 4.4e-14 52.3 0.3 1.5e-13 50.6 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63518.1 - 6.4e-10 38.9 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG63518.1 - 0.0084 16.3 0.6 0.026 14.8 0.6 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG63520.1 - 2.9e-32 112.0 0.0 7.7e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63520.1 - 3.9e-31 107.0 0.0 9.4e-31 105.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63520.1 - 8.3e-27 93.5 0.0 2e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63520.1 - 2.1e-18 66.1 0.2 6.2e-18 64.7 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63520.1 - 7.1e-15 55.3 0.0 2.8e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG63520.1 - 1.1e-06 28.4 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG63520.1 - 3.8e-06 27.4 0.0 4.4e-05 24.0 0.0 2.7 3 0 0 3 3 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG63520.1 - 9.1e-05 22.6 0.0 0.00045 20.4 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG63520.1 - 0.00014 22.4 0.0 0.00042 20.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG63520.1 - 0.00042 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Phage_GPO PF05929.11 GBG63520.1 - 0.0096 15.6 5.1 1.6 8.3 0.0 2.6 2 1 0 2 2 2 2 Phage capsid scaffolding protein (GPO) serine peptidase IFRD PF05004.13 GBG63520.1 - 0.012 14.8 3.6 0.022 13.9 3.6 1.4 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Laminin_II PF06009.12 GBG63520.1 - 0.035 14.1 2.2 0.077 13.0 2.2 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF5344 PF17279.2 GBG63520.1 - 0.78 10.4 3.1 0.59 10.7 0.9 1.9 2 0 0 2 2 1 0 Family of unknown function (DUF5344) WD40_alt PF14077.6 GBG63521.1 - 0.0071 16.2 0.0 0.27 11.1 0.0 2.7 2 0 0 2 2 2 1 Alternative WD40 repeat motif Nop14 PF04147.12 GBG63522.1 - 0.17 10.1 28.1 0.2 9.8 28.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG63522.1 - 1 8.7 32.1 1.3 8.4 32.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG63522.1 - 1.1 7.5 23.1 1.5 7.0 23.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG63522.1 - 2.9 7.4 17.8 4.2 6.9 17.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIF_alpha PF05793.12 GBG63522.1 - 5.2 5.5 27.6 8.8 4.8 27.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zip PF02535.22 GBG63522.1 - 8.1 5.6 8.3 9.4 5.3 8.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RT_RNaseH_2 PF17919.1 GBG63523.1 - 1.3e-56 188.8 0.0 5.2e-27 93.8 0.0 2.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63523.1 - 3.8e-49 165.3 0.0 1.9e-24 85.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63523.1 - 1.5e-36 126.0 0.0 4.7e-25 88.4 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG63523.1 - 0.043 14.1 12.1 0.074 13.3 12.1 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2249 PF10006.9 GBG63523.1 - 0.077 12.9 0.1 10 6.1 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) SDA1 PF05285.12 GBG63523.1 - 1.9 7.8 21.6 2.9 7.2 21.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG63523.1 - 3.2 5.9 15.5 4.9 5.3 15.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH PF17917.1 GBG63524.1 - 2.4e-22 79.2 0.0 8.6e-22 77.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63524.1 - 3.4e-21 75.1 0.0 7.6e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1664 PF07889.12 GBG63524.1 - 0.048 13.7 0.3 0.048 13.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_attach PF05354.11 GBG63524.1 - 0.11 12.3 0.0 4 7.3 0.0 2.5 2 0 0 2 2 2 0 Phage Head-Tail Attachment Bap31_Bap29_C PF18035.1 GBG63524.1 - 0.55 10.3 5.1 1.8 8.6 5.1 1.9 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain TMF_TATA_bd PF12325.8 GBG63524.1 - 2.7 8.3 13.2 0.081 13.2 2.7 3.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 GBG63524.1 - 3.7 8.2 8.9 0.16 12.6 1.8 2.5 2 0 0 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 GBG63524.1 - 6 6.9 18.2 1.6 8.8 10.5 3.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 GBG63524.1 - 9.9 6.0 13.3 0.13 12.1 0.8 3.4 3 0 0 3 3 3 0 Septum formation initiator RT_RNaseH_2 PF17919.1 GBG63525.1 - 6.9e-47 157.6 0.0 6.2e-27 93.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63525.1 - 3.4e-33 114.1 0.0 4.4e-24 84.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63525.1 - 1.5e-25 90.1 0.0 2.6e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG63525.1 - 4.4e-19 68.3 0.2 1.5e-18 66.7 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain COR PF16095.5 GBG63525.1 - 3e-07 30.5 0.1 1.1e-06 28.6 0.0 2.0 3 0 0 3 3 3 1 C-terminal of Roc, COR, domain rve PF00665.26 GBG63525.1 - 1.5e-06 28.4 0.0 4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG63525.1 - 1.2e-05 25.1 3.2 3.7e-05 23.6 3.2 1.9 1 0 0 1 1 1 1 Zinc knuckle Chromo PF00385.24 GBG63525.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC_2 PF13696.6 GBG63525.1 - 0.029 14.2 4.1 0.073 12.9 4.1 1.8 1 0 0 1 1 1 0 Zinc knuckle HNH_3 PF13392.6 GBG63525.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease DUF3807 PF12720.7 GBG63525.1 - 0.68 10.2 16.5 1.8 8.8 16.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Mpp10 PF04006.12 GBG63525.1 - 0.9 7.9 25.7 1.4 7.2 25.7 1.2 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG63525.1 - 2.6 7.4 25.4 4.8 6.5 25.4 1.3 1 0 0 1 1 1 0 SDA1 DUF4746 PF15928.5 GBG63525.1 - 7.2 5.9 18.6 19 4.5 18.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) WD40_alt PF14077.6 GBG63526.1 - 0.02 14.8 0.3 0.45 10.4 0.1 3.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif Cu2_monoox_C PF03712.15 GBG63526.1 - 0.075 12.5 0.2 8 6.0 0.0 2.3 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DUF3787 PF12655.7 GBG63526.1 - 0.25 11.3 0.9 12 5.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) Roc PF08477.13 GBG63527.1 - 3.7e-07 30.4 0.0 2e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 GBG63527.1 - 0.00015 21.7 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain MMR_HSR1 PF01926.23 GBG63527.1 - 0.014 15.4 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 GBG63527.1 - 0.026 14.0 0.0 0.067 12.6 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Ras PF00071.22 GBG63527.1 - 0.062 12.9 0.0 0.2 11.2 0.0 1.9 1 0 0 1 1 1 0 Ras family WD40_alt PF14077.6 GBG63527.1 - 0.11 12.4 0.0 0.66 9.9 0.0 2.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif LMBR1 PF04791.16 GBG63528.1 - 0.032 13.1 1.1 0.043 12.7 1.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CSRNP_N PF16019.5 GBG63528.1 - 0.06 13.3 6.9 0.049 13.5 0.9 2.0 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus COR PF16095.5 GBG63529.1 - 9.9e-11 41.8 0.0 5.3e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 GBG63529.1 - 6e-08 32.9 0.0 4.2e-07 30.2 0.0 2.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GBG63529.1 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIP3 PF03915.13 GBG63529.1 - 0.0015 17.7 0.3 0.0048 16.0 0.0 1.8 2 0 0 2 2 2 1 Actin interacting protein 3 ZapB PF06005.12 GBG63529.1 - 0.015 15.7 0.4 0.043 14.2 0.4 1.8 1 0 0 1 1 1 0 Cell division protein ZapB Arf PF00025.21 GBG63529.1 - 0.017 14.6 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family Ras PF00071.22 GBG63529.1 - 0.021 14.4 0.0 0.095 12.3 0.0 2.2 2 0 0 2 2 2 0 Ras family RNA_helicase PF00910.22 GBG63529.1 - 0.22 12.0 0.5 0.75 10.2 0.0 2.2 3 0 0 3 3 3 0 RNA helicase Noelin-1 PF12308.8 GBG63529.1 - 2.4 8.2 5.2 4.5 7.3 0.4 2.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein Ribosomal_S9 PF00380.19 GBG63530.1 - 2.5e-42 144.2 0.2 4.1e-42 143.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 COR PF16095.5 GBG63531.1 - 1.6e-11 44.4 0.0 5.2e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 GBG63531.1 - 1.2e-07 32.0 0.1 8.3e-07 29.2 0.0 2.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GBG63531.1 - 0.011 15.3 0.0 0.049 13.2 0.0 2.1 2 0 0 2 2 2 0 Ras family Arf PF00025.21 GBG63531.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GBG63531.1 - 0.091 12.8 0.0 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 GBG63531.1 - 0.2 10.4 0.0 0.51 9.1 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MULE PF10551.9 GBG63533.1 - 4e-19 68.8 0.0 1.5e-18 67.0 0.0 2.1 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG63533.1 - 1.6e-15 56.8 0.1 4.3e-15 55.4 0.1 1.8 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.18 GBG63533.1 - 2.2e-06 26.8 0.0 3.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.17 GBG63533.1 - 2e-05 24.1 2.7 4.8e-05 22.9 2.7 1.6 1 0 0 1 1 1 1 SWIM zinc finger FTR_C PF02741.15 GBG63533.1 - 0.047 13.7 0.5 6 6.9 0.1 3.2 3 0 0 3 3 3 0 FTR, proximal lobe Csm1_B PF18211.1 GBG63533.1 - 0.068 13.0 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Csm1 subunit domain B DUF1478 PF07349.11 GBG63533.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) zf-C2H2_10 PF16588.5 GBG63533.1 - 0.2 11.4 6.5 0.64 9.8 6.5 1.9 1 0 0 1 1 1 0 C2H2 zinc-finger CAP_N PF01213.19 GBG63534.1 - 1.6 8.1 9.6 0.17 11.4 4.0 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal RT_RNaseH_2 PF17919.1 GBG63535.1 - 2.6e-35 120.4 0.0 4e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63535.1 - 6.4e-32 110.0 0.0 1.1e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63535.1 - 2.3e-08 33.8 0.0 3.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_64 PF09258.10 GBG63537.1 - 1.2e-39 136.1 0.0 2.4e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain RVT_1 PF00078.27 GBG63537.1 - 3e-25 89.1 0.0 5.3e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glycos_transf_2 PF00535.26 GBG63537.1 - 0.033 14.0 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 CDC27 PF09507.10 GBG63538.1 - 0.024 14.0 48.7 0.029 13.8 48.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 GBG63538.1 - 0.038 13.6 29.7 0.045 13.3 29.7 1.1 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 GBG63538.1 - 0.08 11.7 33.5 0.11 11.3 33.5 1.0 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 GBG63538.1 - 0.33 10.7 25.9 0.42 10.4 25.9 1.1 1 0 0 1 1 1 0 AAA domain DUF966 PF06136.13 GBG63538.1 - 0.44 10.2 22.9 0.49 10.1 22.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PA26 PF04636.13 GBG63538.1 - 0.52 9.2 15.6 0.53 9.1 15.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CCSAP PF15748.5 GBG63538.1 - 1.3 9.2 38.8 1.7 8.7 38.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Asp-B-Hydro_N PF05279.11 GBG63538.1 - 1.6 8.8 35.0 1.7 8.6 35.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4776 PF16003.5 GBG63538.1 - 1.6 7.6 32.6 1.8 7.5 32.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF5427 PF10310.9 GBG63538.1 - 2.8 6.8 36.2 4 6.3 36.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) AF-4 PF05110.13 GBG63538.1 - 2.9 5.9 41.1 3.1 5.8 41.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein VIR_N PF15912.5 GBG63538.1 - 2.9 7.4 27.2 4.3 6.8 27.2 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4551 PF15087.6 GBG63538.1 - 3.7 6.3 21.3 3.9 6.2 21.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3807 PF12720.7 GBG63538.1 - 3.9 7.7 42.5 7.1 6.9 42.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Hamartin PF04388.12 GBG63538.1 - 4.8 5.7 22.0 5.4 5.6 22.0 1.0 1 0 0 1 1 1 0 Hamartin protein Mitofilin PF09731.9 GBG63538.1 - 5.8 5.6 41.2 6.4 5.5 41.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SID-1_RNA_chan PF13965.6 GBG63538.1 - 5.9 5.2 11.1 7.2 4.9 11.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NHL PF01436.21 GBG63539.1 - 0.021 14.9 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 0 NHL repeat SR-25 PF10500.9 GBG63539.1 - 1.7 8.2 12.2 0.17 11.5 7.1 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tim17 PF02466.19 GBG63540.1 - 5.7e-25 87.9 5.2 5.7e-25 87.9 5.2 2.4 3 0 0 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family DUF659 PF04937.15 GBG63541.1 - 2.8e-17 63.0 1.3 4.9e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RNA_pol_Rpb2_6 PF00562.28 GBG63541.1 - 0.021 13.9 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 K_channel_TID PF07941.11 GBG63542.1 - 0.006 17.0 2.1 0.006 17.0 2.1 3.3 3 1 1 4 4 4 1 Potassium channel Kv1.4 tandem inactivation domain rRNA_processing PF08524.11 GBG63542.1 - 0.26 11.3 6.1 0.52 10.3 6.1 1.4 1 0 0 1 1 1 0 rRNA processing MORN PF02493.20 GBG63544.1 - 1.1e-27 94.2 54.0 9.4e-08 31.5 1.1 8.4 9 1 0 9 9 9 6 MORN repeat MORN_2 PF07661.13 GBG63544.1 - 0.21 11.9 0.3 0.21 11.9 0.3 4.0 4 0 0 4 4 4 0 MORN repeat variant DUF659 PF04937.15 GBG63545.1 - 3.2e-16 59.5 0.0 9.3e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63545.1 - 0.00014 21.6 0.5 0.0004 20.1 0.3 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-C2HE PF16278.5 GBG63545.1 - 0.022 15.2 0.3 0.073 13.5 0.3 1.9 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Paf1 PF03985.13 GBG63545.1 - 0.81 8.6 8.4 1.1 8.1 8.4 1.2 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 GBG63545.1 - 2.7 6.2 5.3 3.5 5.8 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SAD_SRA PF02182.17 GBG63546.1 - 4e-28 98.1 0.6 8.7e-28 97.0 0.6 1.5 1 0 0 1 1 1 1 SAD/SRA domain ORC_WH_C PF18137.1 GBG63546.1 - 4 7.5 9.2 1.8 8.7 2.6 2.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal RNA_pol_3_Rpc31 PF11705.8 GBG63546.1 - 4.1 7.6 24.5 4.5 7.5 15.9 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 GBG63546.1 - 4.3 7.1 15.3 0.66 9.7 6.5 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 GBG63546.1 - 4.5 6.6 16.7 5.2 6.4 8.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF3584 PF12128.8 GBG63547.1 - 1 6.8 33.9 0.0033 15.1 17.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fzo_mitofusin PF04799.13 GBG63547.1 - 9.5 5.7 7.8 2.2 7.8 0.7 2.8 2 1 1 3 3 3 0 fzo-like conserved region PRIMA1 PF16101.5 GBG63548.1 - 3.4 7.7 7.2 13 5.9 7.2 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PRIMA1 PF16101.5 GBG63549.1 - 3.3 7.8 7.2 12 5.9 7.2 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ASH PF15780.5 GBG63550.1 - 1.2e-06 28.6 0.5 7 6.9 0.0 6.5 8 0 0 8 8 8 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 GBG63550.1 - 0.00042 20.1 0.0 2.4 8.1 0.0 5.0 5 0 0 5 5 5 1 MSP (Major sperm protein) domain DUF1573 PF07610.11 GBG63550.1 - 0.0018 18.3 0.0 15 5.7 0.0 5.5 6 0 0 6 6 6 1 Protein of unknown function (DUF1573) PapD-like PF14874.6 GBG63550.1 - 0.032 14.4 0.8 2 8.6 0.0 3.7 4 0 0 4 4 4 0 Flagellar-associated PapD-like RT_RNaseH_2 PF17919.1 GBG63551.1 - 8.3e-29 99.6 0.0 2.5e-28 98.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63551.1 - 4.7e-27 94.3 0.0 1.3e-26 92.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63551.1 - 3.4e-25 88.9 0.1 7e-25 87.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG63551.1 - 0.00038 21.0 0.0 0.00074 20.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63551.1 - 0.00041 20.9 0.1 0.00086 19.9 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63551.1 - 0.0029 17.4 0.0 0.031 14.0 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63551.1 - 0.013 15.3 0.1 0.023 14.5 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4746 PF15928.5 GBG63551.1 - 3.8 6.8 11.7 6.3 6.1 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF659 PF04937.15 GBG63552.1 - 3.7e-34 117.8 0.0 6.2e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63552.1 - 7.8e-05 22.4 0.1 0.0002 21.1 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TSC22 PF01166.18 GBG63553.1 - 0.024 15.0 8.4 2.8 8.3 0.2 4.2 2 1 1 4 4 4 0 TSC-22/dip/bun family BRCA2 PF00634.18 GBG63553.1 - 0.049 13.3 0.9 1.3 8.8 0.3 2.6 3 0 0 3 3 3 0 BRCA2 repeat End3 PF12761.7 GBG63553.1 - 0.091 12.9 10.8 0.18 11.9 10.8 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Fez1 PF06818.15 GBG63553.1 - 1.6 9.1 12.9 4.7 7.6 7.8 2.4 1 1 1 2 2 2 0 Fez1 Wbp11 PF09429.10 GBG63553.1 - 1.7 9.1 8.1 1.5 9.2 1.8 2.7 2 1 1 3 3 3 0 WW domain binding protein 11 DUF4404 PF14357.6 GBG63553.1 - 1.9 9.2 5.9 6.5 7.5 5.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) ZapB PF06005.12 GBG63553.1 - 6.4 7.3 15.8 4.6 7.7 3.0 3.2 1 1 2 3 3 3 0 Cell division protein ZapB HALZ PF02183.18 GBG63553.1 - 9.9 6.5 14.5 19 5.6 5.2 4.1 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF659 PF04937.15 GBG63554.1 - 6.1e-29 100.8 0.0 1.4e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63554.1 - 3.8e-07 29.8 0.2 1e-06 28.4 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PK PF00224.21 GBG63556.1 - 4.7e-89 298.7 0.1 6.5e-89 298.2 0.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG63556.1 - 2.8e-21 75.9 0.0 8.1e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GBG63556.1 - 0.0029 16.8 0.9 0.0073 15.5 0.2 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family HydF_dimer PF18128.1 GBG63556.1 - 0.0073 16.3 0.7 2 8.5 0.0 2.8 3 0 0 3 3 3 2 Hydrogen maturase F dimerization domain DnaB_C PF03796.15 GBG63556.1 - 0.063 12.6 0.1 0.18 11.1 0.1 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PK PF00224.21 GBG63558.1 - 3.5e-89 299.1 0.1 5e-89 298.6 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG63558.1 - 2.2e-21 76.2 0.0 6.9e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GBG63558.1 - 0.0025 17.0 0.9 0.0063 15.7 0.2 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family HydF_dimer PF18128.1 GBG63558.1 - 0.0052 16.8 0.7 1.8 8.7 0.0 2.9 3 0 0 3 3 3 2 Hydrogen maturase F dimerization domain DnaB_C PF03796.15 GBG63558.1 - 0.053 12.9 0.1 0.16 11.3 0.1 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Aminotran_4 PF01063.19 GBG63559.1 - 4.3e-31 108.5 0.0 8.6e-27 94.4 0.0 2.4 2 0 0 2 2 2 2 Amino-transferase class IV RVT_1 PF00078.27 GBG63559.1 - 0.0021 17.6 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG63560.1 - 0.0012 17.3 33.2 0.0012 17.3 33.2 2.2 2 0 0 2 2 2 1 CDC45-like protein Nop14 PF04147.12 GBG63560.1 - 0.054 11.7 59.7 0.013 13.7 37.8 2.1 2 0 0 2 2 2 0 Nop14-like family Hid1 PF12722.7 GBG63560.1 - 0.093 10.9 11.6 0.12 10.5 11.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_polI_A34 PF08208.11 GBG63560.1 - 0.19 11.8 46.4 0.17 11.9 26.6 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 CCSAP PF15748.5 GBG63560.1 - 3.2 7.9 35.2 0.02 15.1 17.1 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated TCP PF03634.13 GBG63560.1 - 4.3 7.9 23.8 0.34 11.5 13.1 2.1 2 0 0 2 2 2 0 TCP family transcription factor MAPEG PF01124.18 GBG63561.1 - 1e-22 80.4 2.3 1e-22 80.4 2.3 1.6 2 0 0 2 2 2 1 MAPEG family cNMP_binding PF00027.29 GBG63562.1 - 7.9e-14 51.5 0.7 4.9e-05 23.3 0.0 4.3 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain DUF1664 PF07889.12 GBG63562.1 - 0.0038 17.3 0.3 0.011 15.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) RT_RNaseH_2 PF17919.1 GBG63563.1 - 4.2e-31 106.9 0.0 8.2e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63563.1 - 5e-28 98.1 0.0 8e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63563.1 - 3.1e-24 85.3 0.0 6.1e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rrn6 PF10214.9 GBG63563.1 - 0.42 9.1 5.7 0.68 8.4 5.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RT_RNaseH_2 PF17919.1 GBG63564.1 - 1.5e-31 108.4 0.0 2.5e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63564.1 - 1.4e-28 100.0 0.0 2e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63564.1 - 1.2e-24 86.6 0.0 2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG63565.1 - 4e-28 98.2 0.5 6.3e-28 97.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63565.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region GMP_PDE_delta PF05351.11 GBG63567.1 - 7e-41 139.9 0.0 9.5e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit Myb_DNA-bind_4 PF13837.6 GBG63568.1 - 0.001 19.4 3.5 0.029 14.7 0.1 3.7 4 0 0 4 4 4 2 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 GBG63570.1 - 0.0036 17.6 0.1 0.0071 16.6 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein TSP9 PF11493.8 GBG63572.1 - 0.14 12.8 0.4 0.31 11.7 0.4 1.5 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 K_channel_TID PF07941.11 GBG63572.1 - 0.15 12.5 6.4 3.7 8.1 3.7 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-CCHC PF00098.23 GBG63573.1 - 0.07 13.2 1.9 0.11 12.6 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG63574.1 - 6.7e-27 94.1 0.0 1.1e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63574.1 - 9.7e-13 48.2 0.0 1.6e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG63574.1 - 0.00048 19.8 0.4 0.005 16.5 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG63574.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG63575.1 - 1.9e-09 37.8 2.1 3.2e-09 37.0 2.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG63575.1 - 0.00098 19.2 0.1 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG63575.1 - 0.0065 16.8 0.4 0.013 15.8 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG63575.1 - 0.017 15.3 0.3 0.044 14.0 0.3 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain HemY_N PF07219.13 GBG63575.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Shisa PF13908.6 GBG63575.1 - 0.037 14.3 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator zf-CCHC PF00098.23 GBG63576.1 - 6e-07 29.3 4.1 9.7e-07 28.6 4.1 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF5082 PF16888.5 GBG63576.1 - 0.62 10.3 13.3 0.48 10.7 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) ERM PF00769.19 GBG63576.1 - 7.9 6.2 42.3 0.14 11.9 11.7 3.1 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Menin PF05053.13 GBG63578.1 - 0.28 9.5 9.4 0.39 9.0 9.4 1.2 1 0 0 1 1 1 0 Menin HSP70 PF00012.20 GBG63579.1 - 1.5e-08 33.3 0.0 2e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Myb_DNA-bind_4 PF13837.6 GBG63581.1 - 3.3e-07 30.6 0.1 3.3e-07 30.6 0.1 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG63581.1 - 0.062 13.6 0.1 0.062 13.6 0.1 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RT_RNaseH_2 PF17919.1 GBG63582.1 - 4.7e-30 103.6 0.0 1.6e-29 101.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63582.1 - 2.2e-29 101.8 0.4 7.8e-29 100.0 0.0 2.2 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63582.1 - 9.5e-06 25.6 0.1 1.9e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain REV PF00424.18 GBG63582.1 - 2.6 8.1 8.6 0.29 11.2 0.2 2.9 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) RVT_1 PF00078.27 GBG63584.1 - 2.3e-26 92.7 0.2 4.1e-26 91.9 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63584.1 - 2.4e-05 24.5 0.2 7.8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DUF2408 PF10303.9 GBG63584.1 - 0.011 16.3 0.6 0.032 14.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Dak2 PF02734.17 GBG63584.1 - 0.36 10.7 3.0 0.97 9.3 3.0 1.7 1 0 0 1 1 1 0 DAK2 domain RabGAP-TBC PF00566.18 GBG63586.1 - 1.6e-56 191.3 0.0 2.1e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Retrotrans_gag PF03732.17 GBG63588.1 - 7.1e-06 26.2 0.1 2.1e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein FAT PF02259.23 GBG63588.1 - 0.006 15.8 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 FAT domain Asp_protease_2 PF13650.6 GBG63589.1 - 3.7e-08 33.9 0.0 6.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63589.1 - 7.6e-07 29.6 0.0 1.4e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63589.1 - 1.7e-05 24.6 0.0 3.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63589.1 - 0.00018 21.3 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG63590.1 - 2.8e-10 40.1 0.0 7e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG63590.1 - 0.00014 22.1 12.1 0.0015 18.7 0.0 4.7 5 1 0 5 5 5 2 Retrotransposon gag protein RVT_1 PF00078.27 GBG63590.1 - 0.0088 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MCU PF04678.13 GBG63590.1 - 0.37 10.9 0.0 0.37 10.9 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial calcium uniporter Flot PF15975.5 GBG63590.1 - 3.1 8.0 8.7 3.1 8.0 6.8 2.0 2 0 0 2 2 2 0 Flotillin RabGAP-TBC PF00566.18 GBG63592.1 - 1.1e-56 191.9 0.0 1.5e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YL1 PF05764.13 GBG63593.1 - 0.023 14.8 17.4 0.027 14.6 17.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GBG63593.1 - 0.036 13.5 11.1 0.042 13.3 11.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG63593.1 - 0.12 10.6 12.2 0.15 10.3 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG63593.1 - 0.74 7.9 15.1 1.1 7.4 15.1 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG63593.1 - 1.3 7.7 3.7 1.6 7.4 3.7 1.1 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GBG63593.1 - 1.8 7.8 18.5 2.3 7.5 18.5 1.0 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.10 GBG63593.1 - 2.1 7.6 22.8 2.9 7.2 22.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 GBG63593.1 - 3.6 7.3 10.8 5.2 6.8 10.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 GBG63593.1 - 4.3 5.8 18.5 5.5 5.5 18.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 GBG63593.1 - 4.6 5.2 17.5 6.1 4.8 17.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DDE_Tnp_4 PF13359.6 GBG63595.1 - 2.6e-14 53.2 0.0 6.3e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63595.1 - 2.7e-07 30.4 0.0 4.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Nicastrin PF05450.15 GBG63595.1 - 0.073 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Nicastrin DDE_Tnp_4 PF13359.6 GBG63597.1 - 4.8e-26 91.3 0.0 7e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63597.1 - 1e-10 41.6 0.0 1.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG63597.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain RVT_1 PF00078.27 GBG63598.1 - 4e-17 62.5 0.0 6.9e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 GBG63598.1 - 9.8e-11 42.1 7.9 0.0012 19.7 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Myb_DNA-bind_4 PF13837.6 GBG63598.1 - 0.00024 21.4 0.5 0.00078 19.8 0.5 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG63599.1 - 3.6e-28 97.5 0.0 9.9e-28 96.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63599.1 - 2.9e-27 95.0 0.0 7.6e-27 93.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG63599.1 - 2.1e-06 27.5 0.0 4.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63599.1 - 1.7e-05 25.3 0.0 3.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63599.1 - 0.0006 20.3 0.0 0.0025 18.3 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG63599.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG63599.1 - 0.0065 16.3 0.0 0.043 13.6 0.0 2.2 2 1 0 2 2 2 1 Aspartyl protease WD40 PF00400.32 GBG63600.1 - 1.7e-26 91.9 5.6 0.00021 22.0 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG63600.1 - 1.5e-08 34.8 0.1 0.0012 19.1 0.0 3.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG63600.1 - 0.0012 18.3 0.0 1 8.6 0.0 2.8 1 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 GBG63600.1 - 0.0014 17.4 0.3 1.7 7.2 0.0 3.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Kelch_4 PF13418.6 GBG63600.1 - 0.13 12.3 0.1 0.37 10.8 0.1 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain Med26 PF08711.11 GBG63601.1 - 1.8e-13 50.3 0.0 5.1e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Glyco_transf_22 PF03901.17 GBG63602.1 - 5.4e-77 259.8 26.8 1e-76 258.8 26.8 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Spc7 PF08317.11 GBG63603.1 - 0.0046 15.9 14.6 0.0046 15.9 14.6 5.8 1 1 2 5 5 5 3 Spc7 kinetochore protein RT_RNaseH PF17917.1 GBG63604.1 - 1.1e-32 112.4 0.0 2.1e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63604.1 - 3.1e-30 104.2 0.0 5.9e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63604.1 - 1.9e-15 57.0 0.1 2.8e-15 56.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG63605.1 - 1.5e-08 34.9 5.0 2.8e-08 34.0 5.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG63605.1 - 0.048 13.9 0.5 0.12 12.6 0.5 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Serinc PF03348.15 GBG63606.1 - 1.1e-74 252.0 6.3 3.7e-74 250.2 6.3 1.7 1 1 0 1 1 1 1 Serine incorporator (Serinc) CBS PF00571.28 GBG63607.1 - 9.7e-18 64.4 2.4 4e-09 36.8 0.1 3.8 4 1 0 4 4 4 2 CBS domain TIG PF01833.24 GBG63608.1 - 1.9e-09 37.5 0.0 3.3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 IPT/TIG domain DUF677 PF05055.12 GBG63608.1 - 0.028 13.3 0.4 0.041 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DDE_Tnp_4 PF13359.6 GBG63609.1 - 3.3e-15 56.1 0.0 6.1e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63609.1 - 2.6e-08 33.7 0.0 5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG63609.1 - 0.0038 16.9 0.0 0.0078 15.9 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain Asp_protease_2 PF13650.6 GBG63611.1 - 2e-07 31.5 0.0 1.4e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63611.1 - 1.6e-05 25.4 0.0 4.7e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG63611.1 - 8.4e-05 22.8 0.1 0.00069 19.8 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG63611.1 - 0.00085 19.1 0.1 0.0047 16.7 0.0 2.3 2 1 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63611.1 - 0.003 17.4 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_C48 PF02902.19 GBG63613.1 - 3.3e-26 92.5 0.0 1.2e-25 90.6 0.0 1.7 1 1 1 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Fe_dep_repress PF01325.19 GBG63615.1 - 0.078 13.2 0.0 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain FERM_F1 PF18379.1 GBG63615.1 - 0.2 11.7 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 FERM F1 ubiquitin-like domain Pkinase PF00069.25 GBG63616.1 - 1.3e-71 241.1 0.0 2.2e-71 240.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63616.1 - 3.7e-50 170.6 0.0 8.3e-50 169.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 GBG63616.1 - 4.3e-08 32.9 5.4 6 7.1 0.1 7.9 7 2 0 7 7 7 2 Armadillo/beta-catenin-like repeat Pkinase_fungal PF17667.1 GBG63616.1 - 4.2e-05 22.5 0.0 0.00013 20.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase V-ATPase_H_C PF11698.8 GBG63616.1 - 0.011 15.9 0.2 0.04 14.0 0.1 2.0 2 0 0 2 2 2 0 V-ATPase subunit H Kinase-like PF14531.6 GBG63616.1 - 0.033 13.5 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like GlutR_N PF05201.15 GBG63616.1 - 0.04 13.7 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain FTA2 PF13095.6 GBG63616.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF3361 PF11841.8 GBG63616.1 - 1.2 9.0 3.1 4.8 7.1 0.0 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) DDE_1 PF03184.19 GBG63617.1 - 4.5e-11 42.7 0.1 5.8e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease O-antigen_lig PF13425.6 GBG63619.1 - 0.019 13.8 3.7 0.022 13.6 3.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DCP2 PF05026.13 GBG63620.1 - 1.1e-27 96.2 2.3 2e-27 95.3 2.3 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 GBG63620.1 - 5e-16 58.9 0.0 9.6e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4573 PF15140.6 GBG63620.1 - 0.3 10.8 7.9 0.83 9.4 7.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4573) ATP-synt_F PF01990.17 GBG63621.1 - 5.2e-30 103.6 0.1 6e-30 103.4 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit SF3b1 PF08920.10 GBG63622.1 - 8.2e-45 152.1 29.0 1.4e-43 148.1 6.3 3.9 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.22 GBG63622.1 - 1e-12 47.1 6.7 0.017 15.3 0.0 9.4 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 GBG63622.1 - 4.7e-11 42.9 9.2 0.13 12.7 0.0 8.3 5 2 2 8 8 8 4 HEAT repeats Cnd1 PF12717.7 GBG63622.1 - 3.1e-09 37.1 4.3 0.02 14.9 0.0 6.4 5 2 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GBG63622.1 - 5.1e-09 36.4 4.3 0.29 11.7 0.0 7.2 7 2 0 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GBG63622.1 - 7.7e-05 23.2 0.4 1.1 9.9 0.0 4.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 GBG63622.1 - 0.0065 16.6 1.6 3.4 7.8 0.0 4.4 1 1 6 7 7 7 1 Parkin co-regulated protein Adaptin_N PF01602.20 GBG63622.1 - 0.0077 14.8 0.6 0.18 10.4 0.0 2.8 2 2 0 2 2 2 1 Adaptin N terminal region UME PF08064.13 GBG63622.1 - 0.0093 15.9 4.0 1.2 9.1 0.0 5.3 7 1 0 7 7 7 1 UME (NUC010) domain Dopey_N PF04118.14 GBG63622.1 - 0.015 14.5 1.6 10 5.1 0.0 3.8 3 1 1 4 4 4 0 Dopey, N-terminal MMS19_N PF14500.6 GBG63622.1 - 0.036 13.7 0.2 22 4.5 0.0 3.9 4 2 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II NUC173 PF08161.12 GBG63622.1 - 0.06 13.0 0.1 11 5.6 0.0 3.9 2 1 0 3 3 3 0 NUC173 domain UNC45-central PF11701.8 GBG63622.1 - 0.13 12.3 0.1 0.36 10.8 0.1 1.8 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central TAF6_C PF07571.13 GBG63622.1 - 0.14 12.5 0.0 0.72 10.2 0.0 2.3 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Methyltr_RsmB-F PF01189.17 GBG63623.1 - 1.2e-35 123.0 0.0 4e-18 65.8 0.0 2.7 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PUA PF01472.20 GBG63623.1 - 6.8e-08 32.4 2.6 6.8e-08 32.4 2.6 2.6 2 1 0 2 2 2 1 PUA domain F-box-like PF12937.7 GBG63623.1 - 9.2e-05 22.3 0.0 0.00026 20.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like Methyltransf_31 PF13847.6 GBG63623.1 - 0.0033 17.2 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 GBG63623.1 - 0.0086 16.2 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 GBG63623.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 GBG63623.1 - 0.1 13.3 0.0 0.4 11.4 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 GBG63623.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RT_RNaseH_2 PF17919.1 GBG63624.1 - 1.1e-30 105.6 0.0 1.6e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63624.1 - 1.6e-30 105.5 0.0 2.5e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63624.1 - 5e-08 32.7 0.1 7e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PEPcase PF00311.17 GBG63625.1 - 1.1e-288 959.7 0.1 3.1e-288 958.2 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 GBG63625.1 - 2.9e-05 22.8 0.0 5.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Ca_chan_IQ PF08763.11 GBG63625.1 - 0.11 12.7 0.0 3.6 7.9 0.0 3.1 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain zf-CCHC PF00098.23 GBG63625.1 - 0.3 11.2 4.1 0.61 10.3 4.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF416 PF04222.12 GBG63625.1 - 0.68 9.3 6.6 0.33 10.4 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF416) EBP50_C PF09007.11 GBG63625.1 - 4 8.4 6.8 27 5.8 0.2 2.8 2 0 0 2 2 2 0 EBP50, C-terminal DBD_Tnp_Mut PF03108.15 GBG63626.1 - 4.9e-12 45.7 0.1 8.8e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase SpdB PF05122.13 GBG63626.1 - 0.0036 17.4 0.6 0.012 15.8 0.6 1.9 1 0 0 1 1 1 1 Mobile element transfer protein FtsK_SpoIIIE PF01580.18 GBG63626.1 - 0.042 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RVT_1 PF00078.27 GBG63627.1 - 2.7e-30 105.5 0.1 4.6e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63627.1 - 2.6e-28 98.0 0.0 6.1e-15 55.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63627.1 - 9.8e-21 74.0 0.0 2e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63627.1 - 4.1e-13 49.2 0.2 2.2e-12 46.9 0.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG63627.1 - 2.7e-10 40.5 0.0 1e-09 38.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG63627.1 - 3.6e-09 36.4 0.0 8e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 GBG63627.1 - 0.011 15.4 0.3 0.039 13.7 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG63628.1 - 2.3e-32 111.0 0.0 4.7e-32 110.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63628.1 - 7.9e-32 110.6 0.1 1.3e-31 109.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63628.1 - 1.4e-28 99.2 0.1 2.7e-28 98.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG63628.1 - 3e-06 27.7 0.0 6.9e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63628.1 - 9.4e-05 23.0 0.0 0.00019 22.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG63628.1 - 0.0096 15.8 0.5 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1758 PF05585.12 GBG63628.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG63628.1 - 0.029 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63628.1 - 0.087 12.6 0.1 0.27 11.0 0.1 1.8 1 1 0 1 1 1 0 Aspartyl protease DUF2862 PF11061.8 GBG63628.1 - 0.1 12.5 0.1 0.55 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) TOBE_2 PF08402.10 GBG63628.1 - 0.21 11.8 0.7 2.1 8.6 0.0 2.9 3 0 0 3 3 3 0 TOBE domain DEAD PF00270.29 GBG63629.1 - 1.6e-41 142.0 0.0 7.8e-20 71.4 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG63629.1 - 7e-27 94.0 0.0 2.3e-26 92.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GBG63629.1 - 0.0002 21.6 0.0 0.024 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 GBG63629.1 - 0.0017 18.4 0.0 0.015 15.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG63629.1 - 0.12 11.7 0.0 8.1 5.7 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF3172 PF11371.8 GBG63630.1 - 6.2e-58 194.5 0.1 1.1e-57 193.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) DUF3792 PF12670.7 GBG63630.1 - 0.055 13.6 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Fructosamin_kin PF03881.14 GBG63632.1 - 3.5e-95 318.5 0.0 4.4e-95 318.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 GBG63632.1 - 2.1e-11 44.2 0.0 3.4e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GBG63632.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF220 PF02713.14 GBG63634.1 - 9.4e-05 22.4 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF220 Polyketide_cyc PF03364.20 GBG63634.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ZapB PF06005.12 GBG63634.1 - 0.075 13.5 0.2 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Lectin_N PF03954.14 GBG63634.1 - 0.11 12.3 0.2 0.27 11.0 0.2 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain zf-CCHC PF00098.23 GBG63636.1 - 0.00011 22.1 1.3 0.00031 20.7 1.3 1.8 1 0 0 1 1 1 1 Zinc knuckle Vfa1 PF08432.10 GBG63636.1 - 0.22 11.9 15.1 0.46 10.8 15.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-CCHC_3 PF13917.6 GBG63636.1 - 0.81 9.7 5.5 0.12 12.3 0.5 2.2 2 0 0 2 2 2 0 Zinc knuckle AAA_11 PF13086.6 GBG63636.1 - 4 7.1 13.4 6.9 6.4 13.4 1.4 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 GBG63636.1 - 5.1 5.7 7.3 6.3 5.5 7.3 1.2 1 0 0 1 1 1 0 Presenilin Tho2 PF11262.8 GBG63636.1 - 5.9 6.0 11.6 9 5.4 11.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ARID PF01388.21 GBG63637.1 - 2e-12 47.6 0.0 3.7e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Myb_DNA-binding PF00249.31 GBG63637.1 - 0.0098 16.1 0.1 0.049 13.8 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain ATP-synt_D PF01813.17 GBG63638.1 - 0.022 14.6 1.6 0.051 13.4 1.6 1.6 1 0 0 1 1 1 0 ATP synthase subunit D Myb_DNA-binding PF00249.31 GBG63638.1 - 0.1 12.8 0.0 2 8.7 0.1 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain betaPIX_CC PF16523.5 GBG63638.1 - 1.1 9.1 5.1 0.29 11.0 1.4 1.9 2 0 0 2 2 2 0 betaPIX coiled coil SKA2 PF16740.5 GBG63638.1 - 2.2 8.1 7.5 1.7 8.5 0.1 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF16 PF01519.16 GBG63638.1 - 4.7 7.7 7.2 16 6.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 adh_short_C2 PF13561.6 GBG63639.1 - 8.7e-40 136.7 3.9 3.5e-32 111.8 0.4 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GBG63639.1 - 1.9e-26 92.8 4.7 6e-14 51.9 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 GBG63639.1 - 0.00019 21.4 2.3 0.00028 20.9 1.4 1.6 1 1 0 2 2 2 1 KR domain Orn_Arg_deC_N PF02784.16 GBG63639.1 - 0.009 15.4 0.2 0.014 14.8 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain DUF1847 PF08901.11 GBG63639.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) Prenyltrans PF00432.21 GBG63641.1 - 1.2e-33 114.5 5.8 2.1e-11 43.4 0.2 6.0 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 GBG63641.1 - 7.2e-06 25.3 0.0 0.1 11.6 0.0 3.1 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain TonB_N PF16031.5 GBG63641.1 - 1.1 9.7 7.1 0.74 10.3 0.9 2.1 2 0 0 2 2 2 0 TonB polyproline region DUF971 PF06155.12 GBG63643.1 - 6.8e-25 87.5 0.0 2.9e-24 85.5 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Glyco_hydro_28 PF00295.17 GBG63643.1 - 1.9e-20 73.2 0.0 3.6e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 GBG63643.1 - 3.1e-09 37.0 0.1 1.1e-06 28.7 0.0 3.2 2 1 0 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.6 GBG63643.1 - 0.00022 21.1 2.7 1e+02 2.7 0.1 2.5 1 1 0 1 1 1 0 Right handed beta helix region cobW PF02492.19 GBG63644.1 - 1.8e-31 109.1 0.0 2.8e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 GBG63644.1 - 5.1e-05 22.4 0.1 0.012 14.7 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GBG63644.1 - 0.013 15.9 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 GBG63644.1 - 0.042 13.9 0.0 0.086 12.9 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ResIII PF04851.15 GBG63644.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GBG63644.1 - 0.11 12.8 0.0 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GBG63644.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 GBG63644.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pribosyltran PF00156.27 GBG63645.1 - 6.5e-22 77.7 0.0 9.6e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GBG63645.1 - 0.1 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribosomal_60s PF00428.19 GBG63645.1 - 2.9 8.5 10.7 14 6.3 10.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein TRAM_LAG1_CLN8 PF03798.16 GBG63646.1 - 1.8e-10 40.9 12.9 2.1e-10 40.7 12.9 1.0 1 0 0 1 1 1 1 TLC domain RRM_1 PF00076.22 GBG63647.1 - 3.1e-44 148.6 0.0 1.9e-17 62.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG63647.1 - 0.00083 19.3 0.0 1.7 8.7 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GBG63647.1 - 0.0054 16.8 0.0 6.8 6.9 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 GBG63647.1 - 0.026 14.6 0.0 9.2 6.4 0.0 2.8 2 0 0 2 2 2 0 RNA binding motif RRM_2 PF04059.12 GBG63647.1 - 0.039 14.2 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif 2 dsrm PF00035.26 GBG63647.1 - 0.15 12.8 0.1 0.35 11.6 0.1 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif YL1 PF05764.13 GBG63650.1 - 5.2e-33 115.2 19.4 5.2e-33 115.2 19.4 1.7 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 GBG63650.1 - 1.4e-15 56.8 0.1 2.3e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 GBG63650.1 - 0.069 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 HIT zinc finger Cellulose_synt PF03552.14 GBG63651.1 - 0 1149.8 5.6 0 1149.0 5.6 1.3 1 1 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.6 GBG63651.1 - 3.1e-19 68.9 7.3 3.1e-19 68.9 7.3 1.9 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 GBG63651.1 - 9.5e-13 47.7 13.7 2.1e-12 46.6 13.7 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Glyco_trans_2_3 PF13632.6 GBG63651.1 - 6.4e-07 29.5 10.6 2.6e-06 27.5 0.9 2.8 3 0 0 3 3 3 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG63651.1 - 9e-05 22.3 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG63651.1 - 0.18 11.6 0.1 0.82 9.5 0.0 2.1 3 0 0 3 3 3 0 Glycosyltransferase like family 2 K_channel_TID PF07941.11 GBG63651.1 - 7.2 7.1 11.5 18 5.9 11.5 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain AA_kinase PF00696.28 GBG63652.1 - 1e-47 162.8 6.5 1.4e-47 162.3 6.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family Sporozoite_P67 PF05642.11 GBG63652.1 - 0.02 13.0 0.4 0.026 12.6 0.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RT_RNaseH_2 PF17919.1 GBG63653.1 - 2e-28 98.3 0.0 3.9e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63653.1 - 3.9e-27 94.6 0.0 6.9e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63653.1 - 4.5e-14 52.5 0.0 7.4e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG63654.1 - 3.7e-22 78.9 0.0 5.8e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG63654.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease SlyX PF04102.12 GBG63654.1 - 3.4 8.4 6.5 9.6 6.9 0.2 3.1 3 0 0 3 3 3 0 SlyX DUF3752 PF12572.8 GBG63655.1 - 1.7 9.2 9.7 0.17 12.4 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) Spt20 PF12090.8 GBG63655.1 - 9.9 5.7 11.4 1.8 8.1 4.1 2.1 2 0 0 2 2 2 0 Spt20 family RT_RNaseH_2 PF17919.1 GBG63656.1 - 7.1e-24 83.8 0.0 1.5e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63656.1 - 2.3e-19 69.6 0.0 4.3e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63656.1 - 1.6e-18 67.1 0.1 4e-18 65.7 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG63656.1 - 4e-07 30.6 0.0 1.1e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63656.1 - 1.1e-06 29.1 0.0 2.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63656.1 - 1.7e-05 24.6 0.0 5.1e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63656.1 - 6.9e-05 22.6 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease TAXi_N PF14543.6 GBG63657.1 - 4.5e-24 85.7 5.6 7e-24 85.0 5.6 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GBG63657.1 - 1.1e-13 51.3 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 GBG63657.1 - 5.4e-09 35.9 0.0 1.4e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease KGG PF10685.9 GBG63658.1 - 1.5 9.2 8.5 21 5.6 0.0 4.2 4 0 0 4 4 4 0 Stress-induced bacterial acidophilic repeat motif LtuB PF17455.2 GBG63660.1 - 0.18 12.4 1.0 0.91 10.2 0.0 2.6 2 0 0 2 2 2 0 Late transcription unit B MtN3_slv PF03083.16 GBG63661.1 - 4.9e-18 65.0 2.8 4.9e-18 65.0 2.8 2.2 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange DUF1700 PF08006.11 GBG63661.1 - 0.025 14.1 3.5 0.033 13.7 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF2512 PF10710.9 GBG63661.1 - 0.11 12.1 3.1 0.4 10.3 3.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2512) Wzy_C PF04932.15 GBG63661.1 - 0.43 10.2 4.1 0.8 9.3 4.1 1.5 1 1 0 1 1 1 0 O-Antigen ligase DUF202 PF02656.15 GBG63661.1 - 1 9.9 5.8 12 6.4 1.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) GST_C_2 PF13410.6 GBG63662.1 - 7.8e-06 25.8 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GBG63662.1 - 5.3e-05 23.7 0.0 8.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 GBG63662.1 - 0.0093 15.8 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain DUF3022 PF11226.8 GBG63662.1 - 0.033 14.6 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) GST_C PF00043.25 GBG63662.1 - 0.18 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RT_RNaseH_2 PF17919.1 GBG63664.1 - 8e-28 96.4 0.0 1.2e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63664.1 - 9.8e-24 83.7 0.0 1.5e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG63664.1 - 0.12 10.7 4.8 0.15 10.3 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Atrophin-1 PF03154.15 GBG63664.1 - 0.77 8.0 4.4 1.1 7.5 4.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family TFB6 PF17110.5 GBG63664.1 - 0.91 9.2 3.9 7.3 6.3 2.5 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Kinase-PPPase PF03618.14 GBG63665.1 - 4.3e-85 285.6 0.0 5.7e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Kinase/pyrophosphorylase COPI_C PF06957.11 GBG63665.1 - 0.075 11.8 1.3 0.19 10.5 1.0 1.7 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus zf-CCHC PF00098.23 GBG63668.1 - 6.4e-06 26.0 3.0 1.2e-05 25.1 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG63668.1 - 0.00054 19.7 2.9 0.0011 18.7 2.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Radical_SAM_N PF08497.10 GBG63668.1 - 0.28 10.4 3.8 0.44 9.7 3.8 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal BPL_N PF09825.9 GBG63668.1 - 3.3 6.7 9.5 2 7.4 7.6 1.5 1 1 0 1 1 1 0 Biotin-protein ligase, N terminal Cwf_Cwc_15 PF04889.12 GBG63668.1 - 3.9 7.1 24.8 0.5 10.1 19.8 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Peptidase_S41 PF03572.18 GBG63669.1 - 5.8e-44 149.6 0.0 1e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GBG63669.1 - 2.4e-13 49.7 0.2 6.7e-13 48.3 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GBG63669.1 - 7.2e-09 35.9 0.2 1.3e-08 35.0 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GBG63669.1 - 3e-07 30.6 0.1 8.8e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 GBG63669.1 - 0.0043 17.0 0.2 0.026 14.5 0.1 2.3 2 0 0 2 2 2 1 Tricorn protease PDZ domain MatE PF01554.18 GBG63670.1 - 1.1e-68 229.9 22.2 4.3e-35 120.8 9.0 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GBG63670.1 - 3.7e-10 40.0 6.4 3.7e-10 40.0 6.4 4.2 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain RVT_1 PF00078.27 GBG63671.1 - 4.3e-28 98.4 0.1 6.4e-27 94.5 0.0 2.5 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) DnaJ PF00226.31 GBG63671.1 - 9.4e-24 83.3 4.1 1.8e-23 82.4 4.1 1.5 1 0 0 1 1 1 1 DnaJ domain RT_RNaseH_2 PF17919.1 GBG63671.1 - 4.2e-16 58.8 0.0 1.4e-15 57.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63671.1 - 2.7e-08 34.0 0.0 8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG63671.1 - 2.3e-06 28.1 0.0 6.4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63671.1 - 6.2e-06 26.7 0.0 2.3e-05 24.8 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63671.1 - 1.6e-05 24.7 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG63671.1 - 0.00019 21.6 0.2 0.0029 17.8 0.0 3.2 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG63671.1 - 0.0029 17.4 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CLZ PF16526.5 GBG63671.1 - 4.8 7.6 5.8 60 4.1 0.5 3.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BUD22 PF09073.10 GBG63672.1 - 1 8.6 20.9 1.3 8.3 20.9 1.1 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 GBG63672.1 - 7.8 6.2 16.4 12 5.6 16.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_C48 PF02902.19 GBG63673.1 - 7.6e-17 61.9 0.3 1.5e-16 60.9 0.3 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CENP-F_leu_zip PF10473.9 GBG63674.1 - 0.0036 17.3 3.7 0.0036 17.3 3.7 1.6 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 GBG63674.1 - 0.013 14.8 1.1 0.031 13.7 1.1 1.6 1 1 0 1 1 1 0 Tropomyosin ATG16 PF08614.11 GBG63674.1 - 0.033 14.4 2.4 0.14 12.4 2.4 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.6 GBG63674.1 - 0.035 14.2 0.6 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF2046 PF09755.9 GBG63674.1 - 0.039 13.2 1.5 0.058 12.6 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) LPP PF04728.13 GBG63674.1 - 0.048 14.1 0.1 0.97 9.9 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper MscS_porin PF12795.7 GBG63674.1 - 0.062 12.8 2.4 0.092 12.3 2.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain YabA PF06156.13 GBG63674.1 - 0.18 12.5 0.6 0.36 11.5 0.6 1.5 1 0 0 1 1 1 0 Initiation control protein YabA KELK PF15796.5 GBG63674.1 - 0.31 11.5 3.3 0.59 10.6 3.3 1.4 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase H-kinase_dim PF02895.14 GBG63674.1 - 0.53 10.7 2.1 0.57 10.6 0.4 1.9 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain TolA_bind_tri PF16331.5 GBG63674.1 - 0.8 9.8 4.3 18 5.5 0.2 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation ubiquitin PF00240.23 GBG63675.1 - 7.7e-23 80.0 0.5 1.8e-22 78.9 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GBG63675.1 - 2.5e-10 40.0 2.3 4.6e-10 39.2 2.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GBG63675.1 - 0.0045 17.4 0.3 0.022 15.2 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad50_zn_hook PF04423.14 GBG63675.1 - 0.012 15.4 0.2 0.034 14.0 0.2 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif Ubiquitin_5 PF18037.1 GBG63675.1 - 0.069 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain RVT_1 PF00078.27 GBG63676.1 - 0.00014 21.4 0.0 0.15 11.5 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG63677.1 - 0.0018 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63677.1 - 0.0064 17.1 0.1 0.017 15.8 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG63677.1 - 0.099 12.4 0.2 0.46 10.3 0.1 1.9 2 0 0 2 2 2 0 Aspartyl protease cNMP_binding PF00027.29 GBG63677.1 - 0.13 12.4 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain zf-CCHC PF00098.23 GBG63678.1 - 5.4e-06 26.2 3.2 1.2e-05 25.2 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG63678.1 - 0.0002 21.6 0.0 0.00089 19.5 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG63678.1 - 0.0026 18.0 0.0 0.0061 16.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_2 PF13696.6 GBG63678.1 - 0.012 15.4 4.1 0.023 14.5 4.1 1.5 1 0 0 1 1 1 0 Zinc knuckle ATG_C PF09333.11 GBG63678.1 - 0.2 12.0 1.2 0.39 11.1 0.0 2.0 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain SDA1 PF05285.12 GBG63678.1 - 0.48 9.8 24.2 0.77 9.1 24.2 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG63678.1 - 8.7 4.5 17.6 15 3.7 17.6 1.3 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH PF17917.1 GBG63680.1 - 3.3e-29 101.2 0.0 7.2e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63680.1 - 8.5e-24 83.5 0.1 3e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63680.1 - 5.5e-13 48.8 1.4 5.5e-13 48.8 1.4 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG63680.1 - 4.4e-10 39.3 0.0 8.9e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG63680.1 - 5.9e-10 39.4 0.0 1.9e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63680.1 - 0.033 14.4 0.9 0.069 13.4 0.9 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG63681.1 - 1.8e-28 98.5 0.0 3.2e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63681.1 - 1.2e-25 89.9 0.0 2e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63681.1 - 2.8e-16 59.3 0.3 8.2e-16 57.9 0.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63681.1 - 3.8e-12 46.2 0.1 6.6e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG63682.1 - 2.7e-05 24.6 2.9 3e-05 24.4 2.1 1.5 1 1 0 1 1 1 1 Sodium ion transport-associated CDC45 PF02724.14 GBG63682.1 - 0.6 8.3 16.6 0.85 7.8 16.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG63682.1 - 0.78 9.1 22.7 1.2 8.5 22.7 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG63682.1 - 1.6 8.0 23.6 2.9 7.1 23.6 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG63682.1 - 1.9 6.6 24.0 2.8 6.1 24.0 1.2 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 GBG63682.1 - 5 6.4 27.9 9.8 5.5 27.9 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) zf-CCHC PF00098.23 GBG63683.1 - 9.6e-05 22.3 2.5 0.00018 21.4 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle CDV3 PF15359.6 GBG63684.1 - 2 8.9 7.6 0.097 13.2 1.4 1.9 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Sel1 PF08238.12 GBG63685.1 - 2.1e-169 546.1 107.5 3.5e-10 40.2 0.6 24.9 24 0 0 24 24 24 23 Sel1 repeat NOA36 PF06524.12 GBG63685.1 - 0.014 14.8 8.0 0.021 14.2 6.2 2.2 2 0 0 2 2 2 0 NOA36 protein Nop14 PF04147.12 GBG63685.1 - 0.5 8.5 12.3 1.2 7.2 12.3 1.6 1 0 0 1 1 1 0 Nop14-like family Usp PF00582.26 GBG63685.1 - 1.8 9.1 7.1 1.4 9.5 1.1 3.0 2 0 0 2 2 2 0 Universal stress protein family TPR_7 PF13176.6 GBG63685.1 - 2.7 8.2 9.0 1.6 9.0 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat XAP5 PF04921.14 GBG63685.1 - 4.4 7.0 6.7 1.7 8.4 3.5 1.9 2 0 0 2 2 2 0 XAP5, circadian clock regulator DNA_pol_phi PF04931.13 GBG63685.1 - 7.9 4.4 20.2 15 3.6 20.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi PP-binding PF00550.25 GBG63686.1 - 1.9e-10 40.9 0.3 3e-10 40.3 0.3 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site S-layer PF07752.11 GBG63686.1 - 0.057 12.5 0.2 0.078 12.0 0.2 1.2 1 0 0 1 1 1 0 S-layer protein PP-binding PF00550.25 GBG63687.1 - 3.4e-10 40.1 0.2 5.1e-10 39.6 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site S-layer PF07752.11 GBG63687.1 - 0.065 12.3 0.2 0.089 11.8 0.2 1.2 1 0 0 1 1 1 0 S-layer protein DSHCT PF08148.12 GBG63688.1 - 0.076 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain RT_RNaseH_2 PF17919.1 GBG63689.1 - 5.5e-22 77.7 0.0 1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63689.1 - 2.1e-21 76.2 0.0 4.3e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG63689.1 - 5.8e-08 32.6 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63689.1 - 3.3e-07 30.8 0.0 7.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63689.1 - 6.6e-05 23.4 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG63689.1 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease PP-binding PF00550.25 GBG63690.1 - 7.3e-10 39.1 0.2 8.7e-10 38.8 0.2 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site S-layer PF07752.11 GBG63690.1 - 0.014 14.5 0.1 0.016 14.2 0.1 1.0 1 0 0 1 1 1 0 S-layer protein PORR PF11955.8 GBG63693.1 - 5e-51 173.6 3.1 2.7e-30 105.4 0.1 2.2 1 1 1 2 2 2 2 Plant organelle RNA recognition domain Mpp10 PF04006.12 GBG63693.1 - 0.00098 17.7 10.5 0.0014 17.2 10.5 1.2 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.14 GBG63693.1 - 0.036 12.4 12.2 0.055 11.8 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF572 PF04502.13 GBG63693.1 - 0.072 12.7 6.7 0.13 11.9 6.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Sigma70_ner PF04546.13 GBG63693.1 - 4.8 7.0 18.5 12 5.7 18.5 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region RPN2_C PF18004.1 GBG63693.1 - 9.3 6.1 10.1 25 4.8 10.1 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PP-binding PF00550.25 GBG63696.1 - 2.2e-08 34.3 0.1 4.7e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site TPR_14 PF13428.6 GBG63696.1 - 1.6e-06 28.4 15.8 0.094 13.6 1.7 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 GBG63696.1 - 5.9e-05 23.5 11.9 0.32 11.5 5.4 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG63696.1 - 0.00019 21.4 3.9 4.1 7.9 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG63696.1 - 0.00088 19.2 11.7 9.8 6.6 1.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG63696.1 - 0.0029 17.2 1.2 0.26 11.0 0.0 3.5 5 0 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 GBG63696.1 - 0.022 15.1 0.1 0.12 12.8 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG63696.1 - 0.83 9.6 8.6 15 5.6 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG63696.1 - 2.8 8.3 12.1 3.4 8.0 0.9 3.0 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG63696.1 - 6.7 7.4 20.3 0.054 14.2 4.7 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG63696.1 - 8.5 6.4 8.4 54 3.8 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PP-binding PF00550.25 GBG63697.1 - 7.9e-09 35.8 0.1 1.2e-08 35.2 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Lsr2 PF11774.8 GBG63697.1 - 0.12 12.6 0.3 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Lsr2 Ribosomal_L22 PF00237.19 GBG63698.1 - 2.3e-31 108.1 0.1 3.7e-31 107.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L40e PF01020.17 GBG63698.1 - 1.7e-28 98.2 11.3 1.7e-28 98.2 11.3 1.8 2 0 0 2 2 2 1 Ribosomal L40e family zf-C4pol PF14260.6 GBG63698.1 - 0.011 16.2 1.6 0.024 15.1 1.6 1.5 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta RSN1_7TM PF02714.15 GBG63700.1 - 3.8e-77 259.3 16.2 7.6e-77 258.3 16.2 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GBG63700.1 - 6.5e-35 120.2 0.1 6.5e-35 120.2 0.1 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GBG63700.1 - 4.7e-26 92.1 0.0 6.7e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PsbQ PF05757.11 GBG63700.1 - 0.11 12.2 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) RT_RNaseH_2 PF17919.1 GBG63701.1 - 1.4e-16 60.4 0.0 2.8e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63701.1 - 3.9e-10 39.6 0.1 5.4e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63701.1 - 6.9e-06 26.3 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG63701.1 - 1.1 7.4 16.2 1.5 6.9 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG63701.1 - 4.3 6.7 17.6 5.9 6.2 17.6 1.1 1 0 0 1 1 1 0 SDA1 PPDK_N PF01326.19 GBG63702.1 - 2.3e-20 73.1 0.6 1.1e-14 54.5 0.3 4.3 2 1 0 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF2934 PF11154.8 GBG63702.1 - 0.0016 18.1 0.1 1 9.1 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2934) Phage_glycop_gL PF11108.8 GBG63703.1 - 0.093 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Viral glycoprotein L Gp_dh_C PF02800.20 GBG63704.1 - 5.8e-70 234.0 0.0 7.7e-70 233.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG63704.1 - 1.2e-37 128.3 0.0 4e-37 126.6 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG63704.1 - 0.0043 17.2 0.3 0.016 15.3 0.0 2.1 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Radical_SAM PF04055.21 GBG63704.1 - 0.047 14.1 0.0 0.58 10.5 0.0 2.0 2 0 0 2 2 2 0 Radical SAM superfamily EamA PF00892.20 GBG63705.1 - 0.14 12.4 0.8 0.21 11.7 0.8 1.2 1 0 0 1 1 1 0 EamA-like transporter family Titin_Z PF09042.11 GBG63705.1 - 0.81 9.7 5.1 0.46 10.5 2.2 2.2 2 0 0 2 2 2 0 Titin Z Corona_S2 PF01601.16 GBG63706.1 - 0.03 12.8 0.0 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein ApoO PF09769.9 GBG63707.1 - 0.011 15.6 0.1 0.051 13.5 0.0 1.9 2 0 0 2 2 2 0 Apolipoprotein O Apolipoprotein PF01442.18 GBG63707.1 - 0.028 14.3 0.1 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain BAR_3 PF16746.5 GBG63707.1 - 0.12 12.1 0.9 0.13 11.9 0.2 1.4 2 0 0 2 2 2 0 BAR domain of APPL family DUF659 PF04937.15 GBG63708.1 - 8.3e-06 25.7 0.1 1.8e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RPN2_C PF18004.1 GBG63708.1 - 0.058 13.3 1.1 0.12 12.3 1.1 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_pol_3_Rpc31 PF11705.8 GBG63708.1 - 0.061 13.6 6.3 0.099 12.9 6.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 GBG63708.1 - 0.067 12.6 6.9 0.089 12.2 6.9 1.1 1 0 0 1 1 1 0 SDA1 PBP1_TM PF14812.6 GBG63708.1 - 0.16 12.4 3.7 0.36 11.2 3.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 GBG63708.1 - 0.33 10.3 9.7 0.69 9.2 9.7 1.5 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 GBG63708.1 - 6.8 5.7 11.6 10 5.1 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 GBG63708.1 - 8.2 6.2 9.8 18 5.1 9.8 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region HAD_2 PF13419.6 GBG63709.1 - 2.8e-18 66.6 0.0 3.2e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GBG63709.1 - 1.7e-09 38.3 0.0 0.00068 20.0 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GBG63710.1 - 0.00077 19.6 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 GBG63711.1 - 0.00057 19.6 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3138 PF11336.8 GBG63712.1 - 0.15 10.6 2.2 0.29 9.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RRM_1 PF00076.22 GBG63713.1 - 3.3e-18 65.3 0.0 6.7e-10 38.7 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG63713.1 - 2.8e-06 27.3 0.0 0.0022 18.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_9 PF18444.1 GBG63713.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Dimer_Tnp_hAT PF05699.14 GBG63714.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 GBG63714.1 - 0.14 12.2 2.2 0.28 11.2 2.2 1.5 1 0 0 1 1 1 0 BED zinc finger Ribosomal_L38e PF01781.18 GBG63715.1 - 1.4e-34 118.0 1.7 1.6e-34 117.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family RT_RNaseH_2 PF17919.1 GBG63716.1 - 1.6e-23 82.7 0.0 4.8e-23 81.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63716.1 - 2.4e-21 76.0 0.1 6.9e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase MgtE PF01769.16 GBG63716.1 - 9.2e-21 74.5 7.8 3.2e-10 40.4 0.2 2.9 3 0 0 3 3 3 2 Divalent cation transporter Integrase_H2C2 PF17921.1 GBG63716.1 - 3.4e-17 62.3 1.1 1.2e-16 60.6 0.4 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63716.1 - 4.1e-10 39.6 0.2 8.7e-10 38.5 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63716.1 - 1.5e-08 34.9 0.0 4.2e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63716.1 - 0.002 18.3 0.1 0.005 17.0 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger TMP_2 PF06791.13 GBG63716.1 - 0.28 10.8 3.6 3 7.5 3.5 2.4 1 1 1 2 2 2 0 Prophage tail length tape measure protein DEAD PF00270.29 GBG63717.1 - 3e-33 115.0 0.0 8.3e-18 64.8 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Integrase_H2C2 PF17921.1 GBG63717.1 - 5.4e-19 68.1 0.1 1.1e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG63717.1 - 5.6e-17 61.9 2.0 7e-17 61.6 0.6 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63717.1 - 8.6e-13 48.5 0.0 2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG63717.1 - 1.8e-11 44.0 0.1 5.4e-11 42.4 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_S8 PF00082.22 GBG63718.1 - 4.8e-35 121.3 0.1 6.5e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 Subtilase family DnaJ_C PF01556.18 GBG63719.1 - 1.9e-35 122.1 1.1 3e-35 121.5 1.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GBG63719.1 - 1e-27 96.0 5.0 1.6e-27 95.4 5.0 1.3 1 0 0 1 1 1 1 DnaJ domain Peptidase_M17 PF00883.21 GBG63721.1 - 9.2e-114 379.9 0.4 1.3e-113 379.4 0.4 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain CutA1 PF03091.15 GBG63721.1 - 9.1e-36 121.7 0.0 1.7e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Peptidase_M17_N PF02789.17 GBG63721.1 - 1.2e-11 44.5 0.7 4.4e-11 42.7 0.7 2.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Peptidase_M17 PF00883.21 GBG63722.1 - 1.9e-110 369.0 1.3 2.5e-110 368.6 1.3 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 GBG63722.1 - 9.8e-16 57.8 1.0 3.2e-15 56.1 1.0 1.9 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain PDZ_6 PF17820.1 GBG63722.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain zf-HC5HC2H PF13771.6 GBG63723.1 - 2.6e-18 66.1 30.4 4.2e-10 39.8 8.0 4.4 4 0 0 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GBG63723.1 - 9.1e-10 38.7 27.8 2e-07 31.2 6.9 3.9 3 1 1 4 4 4 2 PHD-zinc-finger like domain zf-C3HC4_2 PF13923.6 GBG63723.1 - 8.3e-09 35.2 7.8 8.3e-09 35.2 7.8 2.8 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG63723.1 - 5.4e-07 29.5 9.5 3e-06 27.2 9.5 2.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GBG63723.1 - 1.4e-06 28.5 7.5 1.4e-06 28.5 7.5 4.2 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_3 PF13920.6 GBG63723.1 - 2.6e-06 27.2 6.4 2.6e-06 27.2 6.4 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG63723.1 - 6.9e-06 25.8 6.9 6.9e-06 25.8 6.9 3.2 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG63723.1 - 2.6e-05 24.3 9.4 2.6e-05 24.3 9.4 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING BRCT_2 PF16589.5 GBG63723.1 - 3.7e-05 24.0 0.0 0.21 12.0 0.0 3.1 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain zf-RING_6 PF14835.6 GBG63723.1 - 0.0001 22.1 1.9 0.0001 22.1 1.9 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 GBG63723.1 - 0.00033 20.7 2.9 0.00033 20.7 2.9 2.6 3 0 0 3 3 2 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 GBG63723.1 - 0.00046 20.1 7.1 0.00046 20.1 7.1 4.1 4 0 0 4 4 3 1 zinc-RING finger domain BRCT PF00533.26 GBG63723.1 - 0.0039 17.5 0.0 0.042 14.2 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Prok-RING_4 PF14447.6 GBG63723.1 - 0.0062 16.4 8.9 0.0062 16.4 8.9 3.4 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 RTT107_BRCT_5 PF16770.5 GBG63723.1 - 0.0091 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 GBG63723.1 - 0.082 12.9 1.1 0.22 11.5 0.0 2.3 3 0 0 3 3 2 0 twin BRCT domain TPR_12 PF13424.6 GBG63724.1 - 1.3e-16 60.6 5.5 2e-10 40.8 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG63724.1 - 1.1e-07 31.3 2.7 0.0039 17.1 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG63724.1 - 8.5e-07 28.5 8.3 0.0013 18.5 1.5 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG63724.1 - 9.1e-06 25.4 10.6 0.054 13.6 0.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG63724.1 - 0.00033 20.6 3.9 0.0049 17.0 1.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG63724.1 - 0.0045 17.6 2.6 1.9 9.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG63724.1 - 0.0082 16.0 2.3 4.8 7.2 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG63724.1 - 0.016 15.7 3.5 4 8.0 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG63724.1 - 0.017 15.3 3.0 0.73 10.1 0.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GBG63724.1 - 0.073 13.9 2.3 27 5.9 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat PAP_PilO PF06864.12 GBG63724.1 - 0.078 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF3611 PF12263.8 GBG63725.1 - 1.4e-47 161.9 10.4 1.9e-47 161.5 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Pecanex_C PF05041.15 GBG63728.1 - 0.092 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Pecanex protein (C-terminus) DDRGK PF09756.9 GBG63730.1 - 1.8 8.1 17.3 3.7 7.1 17.3 1.4 1 0 0 1 1 1 0 DDRGK domain NINJA_B PF16136.5 GBG63730.1 - 9.2 6.7 17.6 44 4.5 17.6 2.2 1 0 0 1 1 1 0 Putative nuclear localisation signal Myb_DNA-bind_4 PF13837.6 GBG63731.1 - 6.9e-06 26.4 3.9 6.9e-06 26.4 3.9 2.3 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG63731.1 - 0.02 15.2 2.7 0.17 12.2 0.9 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG63731.1 - 0.027 14.7 8.7 0.036 14.3 1.6 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG63732.1 - 0.00027 21.3 2.7 0.00027 21.3 2.7 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MAP17 PF15807.5 GBG63732.1 - 0.05 13.8 1.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 MADF_DNA_bdg PF10545.9 GBG63732.1 - 0.4 11.0 2.0 2.8 8.3 0.6 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG63733.1 - 4e-18 65.6 0.0 1.7e-17 63.6 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63733.1 - 4.5e-07 29.7 0.0 6.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein TPR_12 PF13424.6 GBG63736.1 - 8.9e-05 22.7 0.6 8.5 6.7 0.1 2.9 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG63736.1 - 0.0053 16.8 3.3 0.12 12.6 0.6 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GBG63736.1 - 0.064 13.5 3.1 9.6 6.7 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG63736.1 - 0.087 12.7 4.0 0.094 12.6 1.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG63736.1 - 0.2 12.3 1.0 34 5.4 0.3 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG63737.1 - 5.1e-26 91.6 0.0 9.2e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63737.1 - 4.9e-20 71.8 0.1 1.3e-19 70.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63737.1 - 7.5e-17 61.2 0.3 2.1e-16 59.8 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG63737.1 - 7.7e-13 48.3 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63737.1 - 1.1e-07 32.0 0.0 2.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG63738.1 - 9.2e-26 89.8 0.0 1.9e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63738.1 - 3.4e-23 81.9 0.0 6.9e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63738.1 - 7.3e-18 64.4 0.6 2.7e-17 62.6 0.5 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG63738.1 - 3.1e-10 40.3 0.0 9.3e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG63738.1 - 0.006 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG63739.1 - 8.5e-17 61.4 0.1 1.7e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG63739.1 - 1.4e-05 25.5 0.0 3.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63739.1 - 0.00011 22.7 0.0 0.00031 21.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG63739.1 - 0.00048 19.9 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63739.1 - 0.00071 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG63739.1 - 0.0049 17.1 2.3 0.0078 16.5 0.3 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Myb_DNA-bind_4 PF13837.6 GBG63741.1 - 0.00083 19.7 0.9 0.0012 19.2 0.9 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG63741.1 - 0.071 13.2 0.1 0.15 12.2 0.2 1.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain REV PF00424.18 GBG63741.1 - 0.18 11.8 0.0 2 8.5 0.0 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) AsmA PF05170.14 GBG63743.1 - 0.014 14.3 0.0 0.045 12.6 0.0 1.7 2 0 0 2 2 2 0 AsmA family MDM1 PF15501.6 GBG63744.1 - 0.21 10.7 13.9 0.29 10.3 13.9 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Poxvirus_B22R PF04395.12 GBG63744.1 - 0.25 10.8 5.8 0.39 10.2 5.8 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein Rxt3 PF08642.10 GBG63744.1 - 0.84 10.4 3.9 2.2 9.1 3.9 1.7 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 Gemini_coat PF00844.18 GBG63744.1 - 0.98 8.8 4.2 3.2 7.1 4.2 1.8 1 1 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family CDC45 PF02724.14 GBG63744.1 - 4.4 5.5 11.3 4.9 5.3 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG63744.1 - 8.4 5.0 8.0 11 4.7 8.0 1.1 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 GBG63744.1 - 8.7 5.8 13.1 13 5.2 13.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF730 PF05325.11 GBG63745.1 - 0.65 10.0 2.7 0.93 9.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF730) DUF5327 PF17261.2 GBG63745.1 - 0.86 10.4 10.1 0.073 13.8 4.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF2457 PF10446.9 GBG63748.1 - 0.62 9.1 8.5 0.87 8.7 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GBG63748.1 - 3.1 5.8 10.5 4.1 5.4 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-bind_4 PF13837.6 GBG63749.1 - 2.7e-08 34.1 2.0 3.1e-08 33.9 1.0 1.7 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG63749.1 - 0.013 15.8 0.3 0.024 14.9 0.3 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Co_AT_N PF12557.8 GBG63750.1 - 1 9.4 10.9 0.04 13.8 4.7 2.0 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal Hexapep PF00132.24 GBG63751.1 - 0.12 12.1 11.7 0.3 10.9 2.2 3.3 2 1 2 4 4 4 0 Bacterial transferase hexapeptide (six repeats) Homeodomain PF00046.29 GBG63754.1 - 3.6e-15 55.6 8.1 6.7e-15 54.7 8.1 1.5 1 0 0 1 1 1 1 Homeodomain HALZ PF02183.18 GBG63754.1 - 8.4e-09 35.5 3.0 8.4e-09 35.5 3.0 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper Homeobox_KN PF05920.11 GBG63754.1 - 0.00083 19.2 1.4 0.002 18.0 1.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain bZIP_1 PF00170.21 GBG63754.1 - 0.052 13.7 2.7 0.14 12.3 2.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor APC_N_CC PF16689.5 GBG63754.1 - 0.088 12.9 0.2 0.28 11.3 0.2 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain NRBF2 PF08961.10 GBG63754.1 - 0.18 11.4 3.8 0.4 10.2 3.8 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator SOGA PF11365.8 GBG63754.1 - 4 8.6 8.6 12 7.1 1.4 2.4 1 1 2 3 3 3 0 Protein SOGA Toxin_10 PF05431.11 GBG63755.1 - 0.0037 16.8 0.5 0.0089 15.5 0.5 1.6 1 0 0 1 1 1 1 Insecticidal Crystal Toxin, P42 DDE_Tnp_4 PF13359.6 GBG63756.1 - 5.7e-29 100.8 0.0 2.1e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63756.1 - 1.6e-14 54.0 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG63756.1 - 9.6e-06 25.4 0.0 0.0035 17.0 0.0 2.5 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG63756.1 - 0.042 14.2 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG63757.1 - 6.1e-09 36.1 2.6 5.4e-08 33.1 0.6 2.9 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain gag-asp_proteas PF13975.6 GBG63758.1 - 1.3e-05 25.6 0.0 2.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63758.1 - 0.0036 17.9 0.0 0.0078 16.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG63758.1 - 0.0077 16.0 1.1 0.013 15.3 1.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG63759.1 - 0.0081 16.4 0.1 0.016 15.4 0.1 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein DUF16 PF01519.16 GBG63760.1 - 0.015 15.8 4.1 0.015 15.8 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 zf-CCHC PF00098.23 GBG63761.1 - 3e-07 30.2 2.0 5.6e-07 29.4 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG63761.1 - 0.0091 15.8 0.7 0.016 15.0 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG63761.1 - 0.082 12.6 0.8 0.15 11.8 0.8 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG63762.1 - 3.1e-08 33.3 3.1 7e-08 32.2 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF3387 PF11867.8 GBG63762.1 - 0.26 10.6 3.0 0.36 10.2 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Ribosomal_S20p PF01649.18 GBG63763.1 - 1.1e-13 51.5 0.4 1.4e-13 51.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S20 RPW8 PF05659.11 GBG63763.1 - 0.027 14.2 0.2 0.032 13.9 0.2 1.1 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Peptidase_S8 PF00082.22 GBG63764.1 - 9.7e-39 133.4 0.1 1.4e-38 132.8 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Casc1_N PF15927.5 GBG63765.1 - 0.1 12.3 11.8 0.2 11.3 11.8 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus RT_RNaseH_2 PF17919.1 GBG63766.1 - 1.3e-29 102.1 0.0 3.9e-16 58.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63766.1 - 6.1e-28 97.9 0.1 1e-27 97.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63766.1 - 3.6e-18 65.8 0.0 7.6e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SelK_SelG PF10961.8 GBG63767.1 - 2.7 8.6 7.0 0.66 10.6 2.4 2.2 2 0 0 2 2 2 0 Selenoprotein SelK_SelG SLC12 PF03522.15 GBG63767.1 - 3 6.8 9.3 3.7 6.5 9.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 GBG63767.1 - 6.3 5.5 15.1 8.3 5.1 15.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GBG63767.1 - 7.3 5.2 18.7 9.9 4.8 18.7 1.3 1 0 0 1 1 1 0 Presenilin DUF659 PF04937.15 GBG63768.1 - 3.6e-39 134.1 0.1 1.3e-38 132.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63768.1 - 0.00015 21.5 0.1 0.00041 20.1 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 GBG63769.1 - 1.2e-27 97.0 0.0 2.7e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG63769.1 - 1.1e-15 57.7 0.0 1.8e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIA PF03153.13 GBG63769.1 - 0.0023 18.0 8.9 0.0023 18.0 8.9 1.7 2 0 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit APG6_N PF17675.1 GBG63769.1 - 0.014 15.9 1.1 0.014 15.9 1.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region BicD PF09730.9 GBG63769.1 - 0.023 13.2 0.1 0.023 13.2 0.1 1.5 2 0 0 2 2 1 0 Microtubule-associated protein Bicaudal-D EzrA PF06160.12 GBG63769.1 - 0.028 12.6 0.1 0.051 11.8 0.1 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1758 PF05585.12 GBG63769.1 - 0.058 13.2 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG63769.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease AAA_23 PF13476.6 GBG63769.1 - 0.07 13.6 3.0 0.16 12.5 3.0 1.5 1 0 0 1 1 1 0 AAA domain APH PF01636.23 GBG63769.1 - 0.086 12.7 0.5 7.6 6.4 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family gag-asp_proteas PF13975.6 GBG63769.1 - 0.087 13.4 0.0 0.26 11.9 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RBD-FIP PF09457.10 GBG63769.1 - 0.089 12.7 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 FIP domain E_Pc_C PF06752.12 GBG63769.1 - 0.14 12.2 11.5 0.25 11.4 11.5 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus CobT PF06213.12 GBG63769.1 - 0.2 11.0 8.3 0.5 9.7 8.3 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Spt20 PF12090.8 GBG63769.1 - 1.3 8.6 22.1 2.7 7.5 22.1 1.4 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 GBG63769.1 - 1.5 8.7 6.6 3 7.8 6.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SPX PF03105.19 GBG63769.1 - 1.9 8.3 18.3 0.027 14.4 6.5 2.1 2 0 0 2 2 2 0 SPX domain Presenilin PF01080.17 GBG63769.1 - 2.2 6.9 3.9 3.2 6.4 3.9 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 GBG63769.1 - 3.4 6.1 7.2 5.6 5.4 7.2 1.2 1 0 0 1 1 1 0 Macoilin family UPF0560 PF10577.9 GBG63769.1 - 3.6 6.0 10.3 5.3 5.4 10.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Atg14 PF10186.9 GBG63769.1 - 3.6 6.6 10.7 0.74 8.8 0.0 2.4 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 ALMT PF11744.8 GBG63769.1 - 7.3 5.3 5.7 5.3 5.8 0.1 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter ATG16 PF08614.11 GBG63769.1 - 7.8 6.7 15.0 6.8 6.9 3.7 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) 2OG-FeII_Oxy_2 PF13532.6 GBG63770.1 - 0.037 14.2 0.8 0.11 12.7 0.8 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Phage_HK97_TLTM PF06120.11 GBG63770.1 - 0.67 9.1 17.9 0.92 8.6 17.9 1.1 1 0 0 1 1 1 0 Tail length tape measure protein MAJIN PF15077.6 GBG63771.1 - 0.84 9.4 7.3 1.1 8.9 7.3 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein RVT_1 PF00078.27 GBG63772.1 - 2.5e-10 40.3 0.3 3.7e-10 39.7 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CTP_transf_like PF01467.26 GBG63773.1 - 2.3e-05 24.6 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Sec23_trunk PF04811.15 GBG63774.1 - 7.5e-70 235.3 0.0 1.1e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GBG63774.1 - 9.6e-22 76.8 0.1 1.6e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GBG63774.1 - 6.5e-21 74.9 0.0 1.7e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GBG63774.1 - 3.3e-16 59.0 3.1 7.7e-16 57.9 3.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GBG63774.1 - 1.4e-09 37.7 0.0 2.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DDE_Tnp_4 PF13359.6 GBG63775.1 - 1.4e-14 54.1 0.0 2.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63775.1 - 7.9e-07 28.9 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein TFIIIC_sub6 PF10419.9 GBG63777.1 - 1.3e-07 31.4 0.0 2.1e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain DNA_pol_A_exo1 PF01612.20 GBG63778.1 - 1.4e-40 138.9 0.1 2e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 GBG63778.1 - 3e-10 39.9 0.1 6.3e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 HRDC domain Sugar_tr PF00083.24 GBG63779.1 - 9.6e-115 384.0 21.7 1.2e-114 383.7 21.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GBG63779.1 - 1.3e-25 90.1 58.6 3.3e-21 75.6 32.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4407 PF14362.6 GBG63779.1 - 0.085 12.2 0.7 0.27 10.5 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CybS PF05328.12 GBG63779.1 - 0.32 10.7 1.1 6.9 6.4 0.0 2.6 2 0 0 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit DUF1129 PF06570.11 GBG63779.1 - 2.9 7.3 7.2 0.84 9.1 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RNA_pol_Rpc34 PF05158.12 GBG63780.1 - 1.8e-16 60.4 0.0 2.3e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit UTP15_C PF09384.10 GBG63781.1 - 0.004 16.9 1.6 0.0059 16.3 0.7 1.7 1 1 0 1 1 1 1 UTP15 C terminal Cep57_MT_bd PF06657.13 GBG63781.1 - 0.0073 16.7 2.1 0.0073 16.7 2.1 2.5 4 0 0 4 4 2 1 Centrosome microtubule-binding domain of Cep57 DUF4055 PF13264.6 GBG63781.1 - 0.0099 16.0 0.6 0.021 15.0 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4055) DUF4088 PF13317.6 GBG63781.1 - 0.015 14.9 0.8 0.028 14.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) EzrA PF06160.12 GBG63781.1 - 0.036 12.3 5.8 0.058 11.6 5.8 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2802 PF10975.8 GBG63781.1 - 0.041 14.0 6.1 0.27 11.4 3.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Retrotrans_gag PF03732.17 GBG63781.1 - 0.083 13.2 1.0 1.8 8.9 0.0 2.8 2 1 0 2 2 2 0 Retrotransposon gag protein Snapin_Pallidin PF14712.6 GBG63781.1 - 0.2 12.1 7.3 0.67 10.4 0.2 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 GBG63781.1 - 1.1 8.7 7.9 0.57 9.7 5.7 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4140 PF13600.6 GBG63781.1 - 3.5 8.1 9.6 4.3 7.9 1.5 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Fmp27_WPPW PF10359.9 GBG63781.1 - 5.2 5.8 9.5 37 3.0 9.5 1.9 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Sel1 PF08238.12 GBG63783.1 - 0 1028.1 173.7 2e-13 50.5 0.1 35.5 36 0 0 36 36 36 35 Sel1 repeat TPR_6 PF13174.6 GBG63783.1 - 1.1e-07 32.0 39.8 0.021 15.4 0.0 17.2 19 2 2 21 21 19 1 Tetratricopeptide repeat Flu_M1_C PF08289.11 GBG63783.1 - 3.8e-07 30.2 7.4 10 6.4 0.0 10.8 9 3 5 14 14 14 1 Influenza Matrix protein (M1) C-terminal domain TPR_7 PF13176.6 GBG63783.1 - 1.4e-06 27.9 11.8 0.79 9.9 0.0 11.3 8 2 2 10 10 10 1 Tetratricopeptide repeat Lysozyme_like PF13702.6 GBG63783.1 - 0.0004 20.1 0.2 0.0023 17.6 0.1 2.4 2 0 0 2 2 2 1 Lysozyme-like TPR_16 PF13432.6 GBG63783.1 - 0.0018 18.9 104.6 0.85 10.3 0.4 19.3 13 5 7 21 21 21 6 Tetratricopeptide repeat YcbB PF08664.10 GBG63783.1 - 0.0048 17.0 0.0 52 3.9 0.0 4.7 4 0 0 4 4 4 0 YcbB domain DUF5630 PF18632.1 GBG63783.1 - 0.054 12.8 1.8 20 4.4 0.0 4.1 5 0 0 5 5 5 0 Family of unknown function (DUF5630) TEX29 PF15839.5 GBG63783.1 - 0.09 13.4 0.6 34 5.1 0.0 5.6 6 0 0 6 6 6 0 Testis-expressed sequence 29 protein TPR_17 PF13431.6 GBG63783.1 - 0.13 12.7 34.9 46 4.7 0.0 15.8 19 1 1 20 20 18 0 Tetratricopeptide repeat pP_pnuc_1 PF18165.1 GBG63783.1 - 0.34 10.8 17.4 71 3.3 0.2 8.5 8 3 3 11 11 11 0 Predicted pPIWI-associating nuclease Dapper PF15268.6 GBG63784.1 - 0.68 8.7 23.5 0.64 8.8 23.5 1.1 1 0 0 1 1 1 0 Dapper Membralin PF09746.9 GBG63784.1 - 1.1 8.2 13.2 1.3 8.0 13.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein zf-CCHC PF00098.23 GBG63785.1 - 0.0012 18.8 1.1 0.0026 17.8 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle Sulfotransfer_1 PF00685.27 GBG63785.1 - 0.48 9.8 3.5 0.99 8.8 3.5 1.5 1 0 0 1 1 1 0 Sulfotransferase domain Sel1 PF08238.12 GBG63786.1 - 0 1044.9 199.4 5.5e-12 46.0 0.2 38.2 39 0 0 39 39 39 37 Sel1 repeat Flu_M1_C PF08289.11 GBG63786.1 - 1.7e-06 28.1 1.7 12 6.2 0.0 9.2 9 3 2 11 11 11 1 Influenza Matrix protein (M1) C-terminal domain TPR_6 PF13174.6 GBG63786.1 - 0.00013 22.4 56.3 0.11 13.2 0.0 19.5 19 4 4 23 23 23 2 Tetratricopeptide repeat YcbB PF08664.10 GBG63786.1 - 0.026 14.6 0.0 23 5.0 0.0 4.4 4 0 0 4 4 4 0 YcbB domain DUF5630 PF18632.1 GBG63786.1 - 0.036 13.4 0.8 7.7 5.8 0.0 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5630) pP_pnuc_1 PF18165.1 GBG63786.1 - 1.2 9.0 13.9 1.6e+02 2.2 0.1 7.6 8 2 2 10 10 10 0 Predicted pPIWI-associating nuclease Myb_DNA-bind_4 PF13837.6 GBG63788.1 - 7.9e-06 26.2 0.9 1.6e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG63788.1 - 0.0023 17.9 0.1 0.0055 16.8 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Glyco_hydro_1 PF00232.18 GBG63788.1 - 0.097 11.1 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Beta_helix PF13229.6 GBG63790.1 - 0.00073 19.4 5.1 0.00073 19.4 5.1 2.7 2 1 0 2 2 2 2 Right handed beta helix region SKIP_SNW PF02731.15 GBG63791.1 - 2.4e-73 245.1 2.2 2.4e-73 245.1 2.2 2.2 2 0 0 2 2 2 1 SKIP/SNW domain RVT_1 PF00078.27 GBG63791.1 - 4.1e-27 95.2 0.0 8.8e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63791.1 - 2.5e-25 88.4 0.0 5.3e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63791.1 - 3.9e-23 81.7 0.0 7.8e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63792.1 - 5.4e-31 106.6 0.0 1.5e-30 105.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63792.1 - 7.7e-31 106.5 0.0 2e-30 105.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63792.1 - 1.4e-19 70.0 0.5 3.1e-19 68.8 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG63792.1 - 1.3e-06 28.2 0.0 3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63792.1 - 2.2e-05 25.0 0.0 5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63792.1 - 0.00035 21.1 0.3 0.0011 19.4 0.0 2.0 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG63792.1 - 0.00047 20.3 0.0 0.0016 18.6 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG63792.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Haem_bd PF14376.6 GBG63792.1 - 2.2 8.2 6.1 2 8.3 4.1 2.0 2 0 0 2 2 2 0 Haem-binding domain Beta_helix PF13229.6 GBG63793.1 - 1.1e-05 25.3 9.3 2.2e-05 24.4 9.3 1.4 1 0 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG63793.1 - 0.018 15.5 31.1 0.32 11.6 0.9 5.8 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TIC20 PF16166.5 GBG63794.1 - 7.5e-37 126.9 3.2 1e-36 126.4 3.2 1.1 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like DDE_Tnp_4 PF13359.6 GBG63796.1 - 1.6e-33 115.6 0.0 2.9e-32 111.5 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63796.1 - 1.5e-17 63.9 0.0 2.4e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG63796.1 - 0.029 14.8 0.1 0.91 9.9 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG63796.1 - 0.041 13.5 0.4 6.5 6.3 0.1 2.6 3 0 0 3 3 3 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG63798.1 - 4.8e-07 30.1 0.2 1.7e-06 28.3 0.2 2.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG63799.1 - 1.5e-33 116.2 0.0 2.3e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG63799.1 - 9e-05 22.1 0.0 0.00029 20.5 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RT_RNaseH_2 PF17919.1 GBG63800.1 - 1e-27 96.1 0.0 1.8e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63800.1 - 2.9e-23 82.1 0.0 5.8e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63800.1 - 1.1e-11 44.7 0.1 1.7e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG63800.1 - 0.48 9.8 8.8 0.69 9.3 8.8 1.1 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 GBG63800.1 - 1 9.6 10.9 1.8 8.9 10.9 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG63800.1 - 4.5 5.4 8.3 6.1 5.0 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DHC_N1 PF08385.12 GBG63801.1 - 2.1e-152 508.7 0.1 9.5e-91 305.1 0.1 5.8 5 2 1 6 6 6 2 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 GBG63801.1 - 2.1e-147 490.4 0.0 2e-145 483.9 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 GBG63801.1 - 1.4e-117 393.1 7.6 1.4e-117 393.1 7.6 5.1 6 2 1 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 GBG63801.1 - 1.5e-104 349.0 0.0 1.8e-103 345.4 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 GBG63801.1 - 2.2e-92 309.5 4.5 3.7e-92 308.8 0.0 3.5 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 GBG63801.1 - 3.3e-86 288.0 0.6 3.3e-86 288.0 0.6 2.7 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 GBG63801.1 - 4.1e-68 228.5 3.4 1.2e-65 220.4 0.0 4.1 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 GBG63801.1 - 2.2e-56 190.2 1.1 1.1e-54 184.6 0.4 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 GBG63801.1 - 3.9e-55 187.3 12.6 3.9e-55 187.3 12.6 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 GBG63801.1 - 1.3e-42 144.7 0.0 1.7e-39 134.6 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 GBG63801.1 - 2e-29 102.4 0.0 3e-11 43.5 0.0 5.7 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 GBG63801.1 - 1.4e-27 96.3 0.1 5.6e-27 94.4 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 GBG63801.1 - 2.7e-14 53.2 0.0 1.2e-13 51.1 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 GBG63801.1 - 2.1e-09 37.9 0.4 0.0017 18.8 0.0 4.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG63801.1 - 4.1e-08 33.6 0.2 0.0011 19.3 0.0 4.9 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 GBG63801.1 - 0.003 17.3 0.6 0.14 11.9 0.0 3.4 4 0 0 4 4 3 1 Sigma-54 interaction domain MbeD_MobD PF04899.12 GBG63801.1 - 0.0036 17.4 0.7 0.12 12.6 0.3 3.6 2 0 0 2 2 2 1 MbeD/MobD like Mg_chelatase PF01078.21 GBG63801.1 - 0.0045 16.4 0.2 0.28 10.6 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI SlyX PF04102.12 GBG63801.1 - 0.016 15.8 0.5 0.016 15.8 0.5 4.9 4 0 0 4 4 3 0 SlyX AAA_30 PF13604.6 GBG63801.1 - 0.019 14.7 1.4 13 5.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 GBG63801.1 - 0.039 13.3 0.1 3.6 6.9 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF853 PF05872.12 GBG63801.1 - 0.054 12.1 0.7 1.9 7.0 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_29 PF13555.6 GBG63801.1 - 0.067 12.9 0.2 26 4.7 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 GBG63801.1 - 0.096 13.1 0.1 30 5.0 0.0 3.8 3 0 0 3 3 3 0 RNA helicase mCpol PF18182.1 GBG63801.1 - 0.15 12.4 1.6 0.5 10.7 0.0 2.8 2 1 1 3 3 2 0 minimal CRISPR polymerase domain MukF_M PF17192.4 GBG63801.1 - 3.6 7.3 8.9 0.86 9.3 1.7 3.0 2 0 0 2 2 2 0 MukF middle domain Na_H_Exchanger PF00999.21 GBG63802.1 - 4.7e-52 177.1 43.3 4.7e-52 177.1 43.3 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family Usp PF00582.26 GBG63802.1 - 0.0002 21.9 1.5 0.066 13.7 0.2 3.1 2 1 0 2 2 2 2 Universal stress protein family DUF1345 PF07077.11 GBG63802.1 - 0.029 14.1 0.6 0.029 14.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) RT_RNaseH_2 PF17919.1 GBG63803.1 - 1.7e-28 98.6 0.0 2.3e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63803.1 - 4.6e-24 84.7 0.0 6.3e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG63804.1 - 2e-07 31.5 0.0 8.3e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63804.1 - 6.4e-07 29.8 0.0 2.3e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG63804.1 - 2.1e-06 27.4 0.2 3.2e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG63804.1 - 1.1e-05 25.2 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG63804.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Senescence_reg PF04520.13 GBG63804.1 - 0.52 11.1 4.0 0.49 11.2 2.1 2.0 2 0 0 2 2 2 0 Senescence regulator RT_RNaseH_2 PF17919.1 GBG63805.1 - 1.2e-27 95.9 0.0 3.2e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63805.1 - 6e-27 94.0 0.0 1.5e-26 92.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63805.1 - 3.9e-16 59.3 0.0 8.5e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG63805.1 - 1.6e-15 56.9 0.1 2.1e-14 53.3 0.1 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG63805.1 - 0.0021 18.2 0.0 0.0054 16.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF2385 PF09539.10 GBG63805.1 - 0.04 14.5 0.2 1.1 9.8 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Rhamno_transf PF11316.8 GBG63805.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF1343 PF07075.11 GBG63806.1 - 9.5e-120 400.1 0.0 1.4e-119 399.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) DUF659 PF04937.15 GBG63807.1 - 1.7e-30 105.9 0.3 3.3e-30 105.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63807.1 - 1e-08 34.8 0.0 2.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ANAPC4_WD40 PF12894.7 GBG63808.1 - 2.8e-11 43.5 2.7 0.028 14.7 0.0 6.8 4 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GBG63808.1 - 8.1e-05 23.3 2.1 11 7.1 0.0 6.4 7 1 0 7 7 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 GBG63808.1 - 0.00012 21.3 0.0 0.00012 21.3 0.0 3.3 5 0 0 5 5 5 1 Coatomer WD associated region eIF2A PF08662.11 GBG63808.1 - 0.00022 21.2 0.2 0.0035 17.2 0.1 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A TPR_1 PF00515.28 GBG63808.1 - 0.0021 17.8 2.5 1.2 9.1 0.2 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG63808.1 - 0.0082 16.4 5.0 11 6.4 0.2 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat Clathrin PF00637.20 GBG63808.1 - 0.011 15.6 1.9 2 8.3 0.1 3.8 2 1 0 3 3 3 0 Region in Clathrin and VPS Vps39_1 PF10366.9 GBG63808.1 - 0.093 13.0 0.3 0.38 11.0 0.3 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 IKI3 PF04762.12 GBG63808.1 - 0.1 10.6 2.8 0.87 7.5 0.1 2.6 3 0 0 3 3 3 0 IKI3 family PD40 PF07676.12 GBG63808.1 - 0.14 12.1 0.0 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Rhodanese_C PF12368.8 GBG63808.1 - 1.1 9.6 7.7 3 8.3 3.7 3.1 2 1 1 3 3 3 0 Rhodanase C-terminal TPR_2 PF07719.17 GBG63808.1 - 1.4 9.2 8.3 0.95 9.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat zinc-ribbons_6 PF07191.12 GBG63808.1 - 2.5 8.1 6.1 18 5.4 6.2 2.3 1 1 0 1 1 1 0 zinc-ribbons TPR_16 PF13432.6 GBG63808.1 - 3 8.6 6.2 10 6.9 0.9 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-4CXXC_R1 PF10497.9 GBG63808.1 - 6.5 7.0 7.7 2.4e+02 2.0 7.7 2.6 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 RNA_pol_3_Rpc31 PF11705.8 GBG63809.1 - 0.0013 19.1 9.3 0.0028 17.9 9.3 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 GBG63809.1 - 0.014 14.8 9.7 0.018 14.4 9.7 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG63809.1 - 0.19 9.9 19.7 0.25 9.5 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG63809.1 - 0.64 8.1 23.0 0.87 7.6 23.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG63809.1 - 0.75 9.2 18.2 1 8.7 18.2 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG63809.1 - 2.2 6.5 14.6 3.2 5.9 14.6 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 GBG63809.1 - 7.6 5.8 18.5 11 5.3 18.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sm_multidrug_ex PF06695.11 GBG63811.1 - 2.9e-38 131.2 3.9 8e-38 129.8 3.9 1.8 1 0 0 1 1 1 1 Putative small multi-drug export protein PHD_Oberon PF07227.11 GBG63812.1 - 9.4e-10 38.5 8.9 2.7e-09 37.0 8.9 1.7 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein MBD PF01429.19 GBG63812.1 - 2.1e-05 24.1 0.0 6.5e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Methyl-CpG binding domain DUF2992 PF11208.8 GBG63812.1 - 1.7 8.9 4.0 3.8 7.8 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) zf-CCHC PF00098.23 GBG63813.1 - 0.0021 18.0 5.5 0.0043 17.1 5.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Fer2 PF00111.27 GBG63815.1 - 4.2e-19 68.3 0.2 6.7e-19 67.6 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Dicty_REP PF05086.12 GBG63816.1 - 9.4 4.1 11.1 12 3.7 11.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SLC12 PF03522.15 GBG63817.1 - 4.8 6.1 8.2 6.5 5.7 8.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PRA1 PF03208.19 GBG63818.1 - 1.2e-13 50.9 1.3 1.8e-13 50.3 1.3 1.2 1 0 0 1 1 1 1 PRA1 family protein Promethin PF16015.5 GBG63818.1 - 9.8 6.2 11.0 7.3 6.6 1.2 2.2 2 0 0 2 2 2 0 Promethin RVT_1 PF00078.27 GBG63820.1 - 0.0078 15.7 0.1 1.8 8.0 0.0 3.1 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) CREPT PF16566.5 GBG63820.1 - 5.3 7.2 5.8 1.8 8.7 0.1 2.7 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour RT_RNaseH_2 PF17919.1 GBG63821.1 - 2.5e-26 91.6 0.0 6.3e-26 90.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63821.1 - 3.4e-24 85.1 0.0 7.9e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63821.1 - 1.3e-09 37.9 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PPP4R2 PF09184.11 GBG63821.1 - 4.9 6.7 8.6 7.1 6.1 8.6 1.2 1 0 0 1 1 1 0 PPP4R2 Retrotrans_gag PF03732.17 GBG63825.1 - 0.0011 19.2 0.1 0.0011 19.2 0.1 3.2 4 0 0 4 4 4 1 Retrotransposon gag protein fn1 PF00039.18 GBG63825.1 - 0.0078 16.4 0.4 0.026 14.7 0.4 1.9 1 0 0 1 1 1 1 Fibronectin type I domain ATP-synt_E PF05680.12 GBG63825.1 - 0.18 12.1 7.8 0.7 10.3 0.2 2.7 2 0 0 2 2 2 0 ATP synthase E chain TFIIE_beta PF02186.15 GBG63825.1 - 0.51 10.7 2.9 1.5 9.1 0.1 2.7 3 0 0 3 3 3 0 TFIIE beta subunit core domain Mt_ATP-synt_B PF05405.14 GBG63825.1 - 0.57 9.8 4.8 1.2 8.7 4.7 1.6 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RRM_1 PF00076.22 GBG63826.1 - 2.9e-16 59.0 1.6 1.6e-07 31.1 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GBG63826.1 - 3.3e-16 59.2 1.2 3.3e-16 59.2 1.2 4.7 4 1 1 5 5 5 1 RNA binding motif La PF05383.17 GBG63826.1 - 1.6e-10 40.9 0.0 4.5e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 La domain Nup35_RRM_2 PF14605.6 GBG63826.1 - 0.051 13.6 0.4 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Myb_DNA-bind_4 PF13837.6 GBG63828.1 - 2.7e-08 34.1 2.7 5.3e-08 33.1 2.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG63828.1 - 0.00072 19.6 1.0 0.0016 18.5 1.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG63828.1 - 0.00099 19.4 1.1 0.0019 18.5 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4653 PF15546.6 GBG63828.1 - 0.13 11.9 0.6 0.23 11.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) RRM_3 PF08777.11 GBG63829.1 - 1.7e-16 60.1 0.3 1.7e-16 60.1 0.3 5.0 4 1 1 5 5 5 1 RNA binding motif RRM_1 PF00076.22 GBG63829.1 - 4.3e-13 48.9 0.3 8.6e-06 25.5 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 GBG63829.1 - 3e-08 33.6 0.0 6.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 La domain Nup35_RRM_2 PF14605.6 GBG63829.1 - 0.046 13.7 0.1 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Keratin_B2 PF01500.17 GBG63830.1 - 2.6 8.0 5.7 0.63 10.0 0.7 2.1 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein Mucin PF01456.17 GBG63831.1 - 0.028 14.4 14.9 0.045 13.7 14.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MAP65_ASE1 PF03999.12 GBG63831.1 - 0.31 9.7 3.6 0.37 9.4 3.6 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Med13_C PF06333.12 GBG63831.1 - 0.89 8.8 7.5 1.1 8.4 7.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF2076 PF09849.9 GBG63831.1 - 2 8.4 7.4 2.6 8.0 7.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Dicty_REP PF05086.12 GBG63831.1 - 2.3 6.1 12.7 2.7 5.8 12.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Es2 PF09751.9 GBG63832.1 - 1.5e-82 278.7 0.1 2.7e-82 277.9 0.0 1.4 2 0 0 2 2 2 1 Nuclear protein Es2 ATG16 PF08614.11 GBG63833.1 - 0.00043 20.6 11.6 0.00043 20.6 11.6 4.9 3 1 1 5 5 5 1 Autophagy protein 16 (ATG16) Filament PF00038.21 GBG63833.1 - 0.011 15.3 3.1 0.011 15.3 3.1 4.6 3 1 1 4 4 4 0 Intermediate filament protein TSC22 PF01166.18 GBG63833.1 - 0.017 15.4 14.2 0.59 10.5 2.2 4.3 3 0 0 3 3 3 0 TSC-22/dip/bun family ADIP PF11559.8 GBG63833.1 - 0.023 14.8 0.7 0.023 14.8 0.7 5.8 4 1 2 6 6 6 0 Afadin- and alpha -actinin-Binding DUF4954 PF16314.5 GBG63833.1 - 0.059 11.5 3.1 0.089 10.9 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) TUDOR PF00567.24 GBG63833.1 - 2 8.5 4.4 10 6.1 0.0 3.0 3 0 0 3 3 3 0 Tudor domain Asp_protease_2 PF13650.6 GBG63834.1 - 2e-06 28.4 0.0 7.9e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63834.1 - 4.1e-06 27.2 0.0 2.3e-05 24.9 0.0 2.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG63834.1 - 4.9e-05 23.1 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG63834.1 - 0.0018 18.5 2.4 0.0035 17.6 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG63834.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease CLZ PF16526.5 GBG63834.1 - 6.7 7.1 8.9 0.77 10.2 0.7 3.4 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PIEZO PF15917.5 GBG63834.1 - 9.4 5.6 8.3 5.4 6.4 4.3 2.1 2 0 0 2 2 2 0 Piezo Integrase_H2C2 PF17921.1 GBG63836.1 - 1.4e-20 73.1 0.1 4e-20 71.7 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63836.1 - 2.5e-15 56.7 0.0 6.2e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG63836.1 - 0.00019 21.0 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63836.1 - 0.0015 18.8 0.1 0.0034 17.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG63836.1 - 0.0017 18.5 0.0 0.005 17.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Spc29 PF17082.5 GBG63836.1 - 0.064 13.1 0.4 0.29 10.9 0.1 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 TAF1_subA PF14929.6 GBG63836.1 - 0.076 12.4 0.1 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A Mcp5_PH PF12814.7 GBG63836.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Dcc1 PF09724.9 GBG63837.1 - 1.4e-67 228.4 0.5 2.4e-67 227.6 0.0 1.6 2 0 0 2 2 1 1 Sister chromatid cohesion protein Dcc1 Rad51 PF08423.11 GBG63837.1 - 1.6e-19 70.2 0.0 5.4e-18 65.2 0.0 2.4 1 1 0 1 1 1 1 Rad51 DBD_Tnp_Mut PF03108.15 GBG63837.1 - 2.3e-14 53.1 0.0 6e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 MuDR family transposase MULE PF10551.9 GBG63837.1 - 7.9e-14 51.9 0.0 1.8e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 GBG63837.1 - 3.4e-06 26.6 1.3 3.4e-06 26.6 1.3 2.0 2 0 0 2 2 2 1 SWIM zinc finger AAA_25 PF13481.6 GBG63837.1 - 4.7e-05 23.1 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GBG63837.1 - 0.00014 21.3 0.0 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 KaiC DUF533 PF04391.12 GBG63837.1 - 0.00032 20.3 0.6 0.026 14.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF533) RecA PF00154.21 GBG63837.1 - 0.0029 17.1 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein CENP-B_dimeris PF09026.10 GBG63837.1 - 0.0033 17.8 0.2 0.0033 17.8 0.2 2.5 2 0 0 2 2 2 1 Centromere protein B dimerisation domain PSY3 PF16836.5 GBG63837.1 - 0.02 14.4 0.0 0.098 12.2 0.0 1.9 2 0 0 2 2 2 0 Shu complex component Psy3, DNA-binding description PPP4R2 PF09184.11 GBG63837.1 - 1.1 8.8 17.7 19 4.8 18.3 2.2 2 0 0 2 2 2 0 PPP4R2 NOA36 PF06524.12 GBG63837.1 - 1.3 8.3 8.7 3.7 6.8 8.7 1.8 1 0 0 1 1 1 0 NOA36 protein Radial_spoke PF04712.12 GBG63837.1 - 1.5 7.7 10.6 2.5 7.0 10.6 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Eapp_C PF10238.9 GBG63837.1 - 3 7.9 7.8 1 9.4 4.3 2.0 2 0 0 2 2 2 0 E2F-associated phosphoprotein Paf1 PF03985.13 GBG63837.1 - 4.6 6.1 16.4 6.5 5.6 15.7 1.5 2 0 0 2 2 2 0 Paf1 RNA_pol_3_Rpc31 PF11705.8 GBG63837.1 - 5.2 7.3 16.0 14 5.9 16.0 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM199X PF15814.5 GBG63837.1 - 5.3 6.0 16.4 13 4.8 16.4 1.5 1 0 0 1 1 1 0 Protein family FAM199X PPL5 PF18168.1 GBG63837.1 - 6 6.1 7.0 11 5.3 7.0 1.3 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 GBG63837.1 - 7.2 6.3 9.9 14 5.4 9.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CRAL_TRIO PF00650.20 GBG63839.1 - 7.6e-26 90.7 0.0 3e-24 85.6 0.0 2.1 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GBG63839.1 - 0.00078 19.6 0.0 0.016 15.4 0.0 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain peroxidase PF00141.23 GBG63840.1 - 3.4e-22 79.3 0.6 1.8e-21 76.9 0.6 1.9 1 1 0 1 1 1 1 Peroxidase UPF1_Zn_bind PF09416.10 GBG63841.1 - 4.6e-71 237.7 4.5 4.6e-71 237.7 4.5 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 GBG63841.1 - 1.4e-58 197.8 0.0 2.4e-58 197.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG63841.1 - 3.3e-47 161.5 7.5 2.9e-28 99.4 0.6 2.7 2 1 1 3 3 2 2 AAA domain DUF5599 PF18141.1 GBG63841.1 - 5.8e-32 109.8 0.0 1.2e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 GBG63841.1 - 1.6e-15 57.3 0.7 1.6e-14 54.1 0.6 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GBG63841.1 - 3.3e-10 40.5 0.1 1.2e-09 38.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 GBG63841.1 - 1e-05 25.6 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 GBG63841.1 - 8.7e-05 22.4 0.1 0.00021 21.2 0.1 1.7 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 GBG63841.1 - 0.00037 19.9 2.6 0.00044 19.6 0.1 2.4 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 GBG63841.1 - 0.0017 17.9 0.1 0.052 13.1 0.1 2.7 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 GBG63841.1 - 0.002 18.4 0.4 0.025 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GBG63841.1 - 0.0032 17.0 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.29 GBG63841.1 - 0.0054 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 GBG63841.1 - 0.01 15.2 0.0 0.035 13.4 0.0 1.8 2 0 0 2 2 2 0 KaiC PIF1 PF05970.14 GBG63841.1 - 0.014 14.6 0.1 2.6 7.1 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase SRP54 PF00448.22 GBG63841.1 - 0.018 14.7 0.1 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 GBG63841.1 - 0.068 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GBG63841.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 GBG63841.1 - 0.082 13.3 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 GBG63841.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ArsA_ATPase PF02374.15 GBG63841.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase Cwf_Cwc_15 PF04889.12 GBG63844.1 - 0.072 12.8 5.3 0.1 12.4 5.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG63844.1 - 1.4 7.2 5.4 1.6 6.9 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Orai-1 PF07856.12 GBG63845.1 - 1.3e-37 129.2 0.2 1.7e-37 128.8 0.2 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity DctQ PF04290.12 GBG63845.1 - 0.27 11.2 6.6 0.94 9.4 1.6 2.4 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Phage_holin_3_6 PF07332.11 GBG63845.1 - 6.5 6.8 7.0 0.54 10.3 0.2 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Orai-1 PF07856.12 GBG63846.1 - 1.5e-11 44.3 0.1 1.5e-11 44.3 0.1 3.4 2 1 1 3 3 3 1 Mediator of CRAC channel activity CitMHS PF03600.16 GBG63846.1 - 2.7e-05 23.5 0.1 2.7e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Citrate transporter Trp_oprn_chp PF09534.10 GBG63846.1 - 0.02 14.7 27.7 0.043 13.6 27.7 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EI24 PF07264.11 GBG63846.1 - 0.43 10.8 11.2 0.33 11.2 8.9 2.0 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) LMF1 PF06762.14 GBG63846.1 - 1.2 8.1 6.2 2.4 7.2 6.2 1.5 1 0 0 1 1 1 0 Lipase maturation factor DUF898 PF05987.13 GBG63846.1 - 2.3 7.2 15.4 5 6.1 15.4 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Orai-1 PF07856.12 GBG63847.1 - 3.1e-19 69.3 0.6 3.1e-19 69.3 0.6 1.4 2 0 0 2 2 2 1 Mediator of CRAC channel activity Kinesin PF00225.23 GBG63848.1 - 3.3e-104 348.4 0.0 6.6e-104 347.4 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG63848.1 - 1.8e-56 190.2 0.1 7.5e-56 188.2 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding OCC1 PF15506.6 GBG63848.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 OCC1 family AAA_22 PF13401.6 GBG63848.1 - 2 8.7 5.0 4.7 7.5 0.0 3.6 3 1 2 5 5 5 0 AAA domain RT_RNaseH_2 PF17919.1 GBG63849.1 - 2.8e-34 117.1 0.0 4.5e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63849.1 - 3.3e-21 75.5 0.0 5.6e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63849.1 - 4.9e-08 32.8 0.1 8e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tubulin PF00091.25 GBG63850.1 - 7.7e-70 235.1 0.1 1.4e-69 234.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG63850.1 - 3.7e-44 149.9 0.2 8.9e-44 148.7 0.2 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain RVT_1 PF00078.27 GBG63850.1 - 6.6e-37 127.2 0.0 1.3e-36 126.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63850.1 - 1.2e-29 102.3 0.0 4.4e-29 100.5 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63850.1 - 4.4e-27 94.4 0.0 1.6e-26 92.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63850.1 - 1.3e-18 66.8 0.5 3e-18 65.6 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG63850.1 - 1.6e-06 27.9 0.0 3.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63850.1 - 9.6e-06 26.2 0.0 2.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Misat_Tub_SegII PF10644.9 GBG63850.1 - 2.4e-05 24.6 0.0 6.9e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain gag-asp_proteas PF13975.6 GBG63850.1 - 0.00053 20.5 0.0 0.0015 19.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG63850.1 - 0.00086 19.5 0.1 0.0028 17.9 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG63850.1 - 0.0039 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Tubulin_2 PF13809.6 GBG63850.1 - 0.0092 15.2 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin like DUF1758 PF05585.12 GBG63850.1 - 0.038 13.7 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Tubulin_3 PF14881.6 GBG63850.1 - 0.073 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain ABC_membrane PF00664.23 GBG63853.1 - 1.3e-106 356.3 19.2 9.4e-58 196.0 9.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GBG63853.1 - 4.7e-71 237.7 0.0 1.6e-34 119.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GBG63853.1 - 1.5e-11 44.2 4.8 0.0011 18.5 0.1 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 GBG63853.1 - 2.5e-09 36.5 0.1 0.003 16.4 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 GBG63853.1 - 2.1e-08 34.8 0.6 0.00029 21.3 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GBG63853.1 - 2.7e-08 34.2 1.0 0.012 15.9 0.2 3.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GBG63853.1 - 1.3e-07 31.3 0.4 0.0089 15.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GBG63853.1 - 6.7e-07 28.8 1.0 0.035 13.4 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin DUF87 PF01935.17 GBG63853.1 - 2.3e-05 24.6 0.1 0.091 12.8 0.0 2.6 3 0 0 3 3 2 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 GBG63853.1 - 2.8e-05 24.1 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 GBG63853.1 - 6.5e-05 22.8 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 GBG63853.1 - 9.3e-05 22.5 0.2 0.76 9.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 GBG63853.1 - 0.00033 20.4 4.1 0.47 10.1 0.4 3.7 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.20 GBG63853.1 - 0.00059 19.1 0.0 0.37 9.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 GBG63853.1 - 0.00082 19.0 2.4 0.28 10.7 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 GBG63853.1 - 0.00087 19.1 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.20 GBG63853.1 - 0.0014 18.6 0.1 0.83 9.5 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_21 PF13304.6 GBG63853.1 - 0.0015 18.4 0.0 11 5.7 0.0 3.4 3 1 1 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GBG63853.1 - 0.0021 18.3 9.1 0.63 10.3 0.4 4.5 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 GBG63853.1 - 0.0035 17.1 1.0 2.6 7.8 0.1 3.5 2 2 0 2 2 2 1 DEAD/DEAH box helicase AAA_7 PF12775.7 GBG63853.1 - 0.0054 16.3 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region SRP54 PF00448.22 GBG63853.1 - 0.019 14.6 0.0 4.3 6.9 0.0 3.2 3 1 0 3 3 3 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 GBG63853.1 - 0.024 13.8 0.0 4.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 GBG63853.1 - 0.031 14.4 0.0 15 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GBG63853.1 - 0.046 14.2 0.2 8.9 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GBG63853.1 - 0.046 13.6 0.1 6 6.7 0.0 2.8 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 GBG63853.1 - 0.05 13.3 0.2 3.2 7.4 0.0 3.2 4 0 0 4 4 4 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 GBG63853.1 - 0.052 13.6 0.0 11 6.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.6 GBG63853.1 - 0.059 12.4 0.0 10 5.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Roc PF08477.13 GBG63853.1 - 0.15 12.3 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 GBG63853.1 - 0.19 12.1 0.0 25 5.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 GBG63853.1 - 0.23 11.3 2.3 23 4.8 0.0 3.8 4 0 0 4 4 4 0 NTPase FERM_N PF09379.10 GBG63853.1 - 0.51 10.3 1.8 36 4.4 0.1 3.1 3 0 0 3 3 3 0 FERM N-terminal domain TPR_19 PF14559.6 GBG63854.1 - 2.9e-29 101.4 79.8 6.7e-05 23.3 0.0 15.5 16 1 1 17 17 16 9 Tetratricopeptide repeat TPR_2 PF07719.17 GBG63854.1 - 1.8e-26 90.1 49.2 0.071 13.2 0.0 19.1 19 0 0 19 19 19 8 Tetratricopeptide repeat TPR_14 PF13428.6 GBG63854.1 - 8.8e-21 72.8 74.8 0.0048 17.6 1.5 20.8 15 7 7 22 22 22 7 Tetratricopeptide repeat TPR_8 PF13181.6 GBG63854.1 - 4.5e-12 45.2 33.1 6.7e-05 22.8 0.2 14.1 16 0 0 16 16 16 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG63854.1 - 2.2e-10 41.0 60.7 0.13 12.9 4.6 13.2 13 4 5 18 18 16 8 Tetratricopeptide repeat TPR_12 PF13424.6 GBG63854.1 - 1.4e-09 38.1 62.0 0.026 14.8 0.0 15.4 13 4 3 16 16 16 6 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG63854.1 - 2.4e-08 34.1 34.0 0.0005 20.3 1.4 10.9 9 2 4 13 13 12 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GBG63854.1 - 1.5e-07 31.3 16.4 11 6.7 0.0 10.4 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG63854.1 - 2.5e-07 30.2 39.9 0.43 10.5 0.5 12.2 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG63854.1 - 4.8e-06 26.2 34.2 0.1 12.3 0.2 11.0 12 1 1 13 13 12 3 TPR repeat TPR_7 PF13176.6 GBG63854.1 - 1.2e-05 24.9 30.9 4 7.7 0.0 11.9 13 0 0 13 13 11 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GBG63854.1 - 0.00093 19.2 14.5 0.14 12.2 0.0 7.9 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat SPOB_a PF14689.6 GBG63854.1 - 0.02 14.6 1.8 9.5 6.0 0.1 4.3 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain PknG_TPR PF16918.5 GBG63854.1 - 0.023 13.4 9.6 0.076 11.7 0.2 4.9 5 0 0 5 5 5 0 Protein kinase G tetratricopeptide repeat YfiO PF13525.6 GBG63854.1 - 0.056 13.2 0.7 0.67 9.6 0.1 3.2 3 0 0 3 3 3 0 Outer membrane lipoprotein TPR_21 PF09976.9 GBG63854.1 - 0.11 12.2 28.4 0.14 11.9 0.1 6.9 7 2 0 8 8 5 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 GBG63854.1 - 0.19 11.4 3.9 4.7 6.9 0.0 4.4 5 0 0 5 5 4 0 26S proteasome subunit RPN7 Alkyl_sulf_dimr PF14863.6 GBG63854.1 - 1 9.8 3.0 19 5.7 0.1 4.0 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_6 PF13174.6 GBG63854.1 - 6 7.7 43.8 0.44 11.3 0.1 12.3 15 0 0 15 15 11 0 Tetratricopeptide repeat TPR_4 PF07721.14 GBG63854.1 - 6.8 7.6 56.7 0.071 13.8 1.1 10.0 12 0 0 12 12 9 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 GBG63854.1 - 9.9 5.8 16.5 0.28 10.8 0.2 4.9 6 0 0 6 6 6 0 Bacterial type III secretion protein (HrpB1_HrpK) GTP1_OBG PF01018.22 GBG63856.1 - 1e-33 116.1 18.0 1.5e-25 89.6 7.6 2.7 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.23 GBG63856.1 - 1.8e-20 73.1 0.0 3.4e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG63856.1 - 2.9e-08 33.4 0.0 2.1e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 GBG63856.1 - 0.0019 17.7 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 GBG63856.1 - 0.038 13.0 0.2 0.28 10.1 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PsbP PF01789.16 GBG63857.1 - 2.8e-10 40.5 0.1 3.4e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 PsbP Aida_C2 PF14186.6 GBG63858.1 - 7.8e-44 148.8 0.0 1.2e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 GBG63858.1 - 1.9e-13 50.7 0.7 3e-12 46.8 0.1 2.2 2 0 0 2 2 2 1 Aida N-terminus Corona_nucleoca PF00937.18 GBG63858.1 - 0.00051 19.2 5.2 0.00073 18.7 5.2 1.1 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein BAF1_ABF1 PF04684.13 GBG63858.1 - 0.11 11.5 3.4 0.16 11.0 3.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Apt1 PF10351.9 GBG63858.1 - 0.2 10.5 3.7 0.25 10.2 3.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FIT1_2 PF17357.2 GBG63858.1 - 0.21 11.7 3.8 0.089 12.9 1.2 1.7 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 RSRP PF17069.5 GBG63858.1 - 2.5 7.6 13.8 3.9 6.9 13.8 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Sel1 PF08238.12 GBG63859.1 - 9.8e-33 111.9 26.3 8.1e-05 23.2 0.1 9.5 9 0 0 9 9 9 8 Sel1 repeat Asp_protease_2 PF13650.6 GBG63859.1 - 1.5e-06 28.7 0.0 4.5e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63859.1 - 3.1e-06 27.6 0.0 8.9e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG63859.1 - 0.0002 21.1 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63859.1 - 0.0021 17.9 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease LapA_dom PF06305.11 GBG63859.1 - 0.099 12.5 1.3 20 5.1 0.0 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Asparaginase PF00710.20 GBG63859.1 - 0.13 11.8 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Asparaginase, N-terminal Retrotrans_gag PF03732.17 GBG63859.1 - 0.13 12.6 0.1 0.34 11.2 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein TPR_17 PF13431.6 GBG63859.1 - 0.92 10.0 3.7 17 6.1 0.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Aida_N PF08910.10 GBG63859.1 - 1.3 9.4 3.5 3.9 7.9 3.5 1.8 1 0 0 1 1 1 0 Aida N-terminus TPR_1 PF00515.28 GBG63859.1 - 2.4 8.1 6.7 35 4.4 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 GBG63860.1 - 5.9e-30 103.0 20.4 5.6e-05 23.7 0.1 7.8 7 0 0 7 7 7 7 Sel1 repeat Asp_protease_2 PF13650.6 GBG63860.1 - 1e-06 29.3 0.0 3e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63860.1 - 1.9e-06 28.3 0.0 5.9e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG63860.1 - 0.00012 21.8 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63860.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease LapA_dom PF06305.11 GBG63860.1 - 0.042 13.7 1.3 14 5.6 0.0 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Retrotrans_gag PF03732.17 GBG63860.1 - 0.081 13.2 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein TPR_17 PF13431.6 GBG63860.1 - 0.29 11.6 3.4 11 6.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Aida_N PF08910.10 GBG63860.1 - 0.78 10.2 3.5 2.6 8.5 3.5 1.9 1 0 0 1 1 1 0 Aida N-terminus TPR_1 PF00515.28 GBG63860.1 - 0.83 9.6 6.7 24 4.9 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 GBG63861.1 - 7e-30 102.8 20.4 5.7e-05 23.6 0.1 7.8 7 0 0 7 7 7 7 Sel1 repeat Asp_protease_2 PF13650.6 GBG63861.1 - 1e-06 29.3 0.0 3e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63861.1 - 2e-06 28.3 0.0 6e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG63861.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63861.1 - 0.0013 18.5 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease LapA_dom PF06305.11 GBG63861.1 - 0.044 13.6 1.3 14 5.6 0.0 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Retrotrans_gag PF03732.17 GBG63861.1 - 0.083 13.2 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein TPR_17 PF13431.6 GBG63861.1 - 0.3 11.6 3.4 11 6.6 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Aida_N PF08910.10 GBG63861.1 - 0.8 10.1 3.5 2.7 8.4 3.5 1.9 1 0 0 1 1 1 0 Aida N-terminus TPR_1 PF00515.28 GBG63861.1 - 0.91 9.5 6.7 25 4.9 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 GBG63862.1 - 0.00025 21.6 0.3 0.0075 16.9 0.1 2.7 2 0 0 2 2 2 1 Sel1 repeat Myosin_head PF00063.21 GBG63865.1 - 6e-231 768.3 0.0 8.4e-231 767.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) RVT_1 PF00078.27 GBG63865.1 - 7.9e-30 104.0 0.1 1.6e-29 103.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63865.1 - 2.4e-23 82.0 0.0 6.3e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63865.1 - 3.3e-21 75.5 0.0 8.9e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63865.1 - 1.5e-16 60.2 0.9 7e-16 58.1 0.2 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG63865.1 - 6.9e-09 35.9 0.0 4.1e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain IQ PF00612.27 GBG63865.1 - 0.00082 19.0 10.8 0.039 13.8 1.8 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif zf-H2C2 PF09337.10 GBG63865.1 - 0.011 16.0 0.1 0.037 14.2 0.1 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Lipin_mid PF16876.5 GBG63866.1 - 0.015 15.4 0.6 0.16 12.2 0.0 2.7 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain PfkB PF00294.24 GBG63867.1 - 4.3e-23 82.1 0.0 6.5e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RVT_1 PF00078.27 GBG63867.1 - 3.7e-06 26.6 0.0 0.069 12.7 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG63868.1 - 6.3e-28 97.8 0.0 1.2e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG63868.1 - 5.1e-07 29.5 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG63868.1 - 7.9e-07 29.6 0.0 3.1e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63868.1 - 1.7e-06 28.6 0.0 4.7e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG63868.1 - 0.048 13.9 0.5 0.048 13.9 0.5 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG63868.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease APG17 PF04108.12 GBG63868.1 - 0.11 11.5 1.9 0.11 11.6 0.3 1.6 2 0 0 2 2 2 0 Autophagy protein Apg17 Tic22 PF04278.12 GBG63869.1 - 1.2e-76 257.4 0.0 2.2e-76 256.5 0.0 1.4 1 0 0 1 1 1 1 Tic22-like family ABC2_membrane_3 PF12698.7 GBG63870.1 - 0.42 9.7 1.3 0.54 9.3 1.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein XPG_I PF00867.18 GBG63871.1 - 3e-31 107.6 0.0 6.5e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GBG63871.1 - 8.4e-30 103.2 0.0 1.6e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 GBG63871.1 - 9.5e-06 26.1 0.0 2.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 GBG63871.1 - 0.0066 17.0 0.1 0.029 15.0 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain 5_3_exonuc_N PF02739.16 GBG63871.1 - 0.032 14.1 0.0 0.084 12.8 0.0 1.7 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain CDC45 PF02724.14 GBG63872.1 - 0.02 13.2 3.9 0.023 13.0 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG63872.1 - 0.058 13.5 4.9 0.073 13.2 4.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 GBG63872.1 - 0.062 11.4 14.7 0.077 11.1 14.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 GBG63872.1 - 0.074 13.3 8.2 0.2 11.9 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GxDLY PF14607.6 GBG63872.1 - 0.11 12.3 0.1 0.31 10.8 0.1 1.7 1 1 1 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type SDA1 PF05285.12 GBG63872.1 - 0.11 11.8 5.9 0.14 11.5 5.9 1.1 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 GBG63872.1 - 0.15 11.7 2.4 0.27 10.9 2.4 1.4 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 GBG63872.1 - 0.17 10.1 6.5 0.2 9.8 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.8 GBG63872.1 - 0.18 10.7 2.0 0.24 10.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BUD22 PF09073.10 GBG63872.1 - 0.26 10.6 3.8 0.31 10.4 3.8 1.2 1 0 0 1 1 1 0 BUD22 Utp14 PF04615.13 GBG63872.1 - 0.32 9.5 5.6 0.38 9.3 5.6 1.1 1 0 0 1 1 1 0 Utp14 protein RRN3 PF05327.11 GBG63872.1 - 0.52 8.8 7.1 0.68 8.4 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 GBG63872.1 - 0.55 9.3 26.1 2.9 6.9 26.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 GBG63872.1 - 0.55 10.2 7.9 1.1 9.2 7.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal SGT1 PF07093.11 GBG63872.1 - 2.9 6.2 7.3 3.9 5.8 7.3 1.1 1 0 0 1 1 1 0 SGT1 protein CENP-B_dimeris PF09026.10 GBG63872.1 - 3.7 8.0 26.0 6.6 7.2 26.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 GBG63872.1 - 8.2 5.6 24.7 13 5.0 24.7 1.2 1 0 0 1 1 1 0 NOA36 protein RVT_1 PF00078.27 GBG63873.1 - 1.7e-28 99.7 0.0 2.5e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG63873.1 - 0.0054 17.0 0.4 0.027 14.7 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein NIF PF03031.18 GBG63873.1 - 0.022 14.5 0.1 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Snapin_Pallidin PF14712.6 GBG63873.1 - 0.08 13.4 0.1 0.25 11.8 0.1 1.9 1 0 0 1 1 1 0 Snapin/Pallidin Lipase_3 PF01764.25 GBG63874.1 - 2.3e-08 34.0 0.1 9.4e-08 32.0 0.1 2.0 1 1 0 1 1 1 1 Lipase (class 3) Mannosyl_trans3 PF11051.8 GBG63876.1 - 4.4e-05 23.0 0.0 7.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 GBG63876.1 - 0.012 15.2 0.1 0.026 14.1 0.1 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 8 RVT_1 PF00078.27 GBG63877.1 - 1.5e-30 106.4 0.0 2.3e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63877.1 - 2.8e-21 75.8 0.0 1e-20 73.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63877.1 - 7.7e-19 67.6 0.0 3.2e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG63877.1 - 7.2e-07 29.8 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63877.1 - 2.6e-06 27.9 0.0 5.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG63877.1 - 7.4e-05 22.5 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG63877.1 - 0.0002 21.4 0.1 0.00043 20.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG63877.1 - 0.00028 20.7 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG63880.1 - 4.8e-30 103.5 0.0 1.1e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63880.1 - 5.9e-29 101.2 0.2 1.2e-28 100.2 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63880.1 - 4.7e-27 94.3 0.0 1e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glyco_trans_4_4 PF13579.6 GBG63881.1 - 0.0051 17.3 0.8 0.01 16.3 0.8 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain NqrM PF04400.13 GBG63881.1 - 0.061 13.1 0.4 0.18 11.6 0.4 1.8 1 0 0 1 1 1 0 (Na+)-NQR maturation NqrM LRR_2 PF07723.13 GBG63881.1 - 0.88 10.4 4.7 22 5.9 0.4 5.1 4 0 0 4 4 4 0 Leucine Rich Repeat SDA1 PF05285.12 GBG63881.1 - 2.1 7.7 11.8 3.3 7.1 11.8 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG63881.1 - 6.7 4.8 12.7 9.7 4.3 12.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG63881.1 - 9.9 4.3 9.8 15 3.8 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG63882.1 - 1.1 7.4 11.6 1.4 7.0 11.6 1.0 1 0 0 1 1 1 0 Nop14-like family DegV PF02645.16 GBG63883.1 - 0.22 10.8 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 RVT_1 PF00078.27 GBG63884.1 - 3.2e-29 102.0 0.9 4.4e-29 101.6 0.2 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63884.1 - 2.8e-24 85.0 0.0 5.5e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63884.1 - 9.9e-22 77.2 0.0 1.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG63884.1 - 0.21 10.7 0.1 6.1 5.8 0.0 2.0 1 1 0 2 2 2 0 Autophagy protein Apg17 Whi5 PF08528.11 GBG63884.1 - 6.2 6.5 5.6 16 5.2 0.4 2.4 2 0 0 2 2 2 0 Whi5 like Ribosomal_L7Ae PF01248.26 GBG63885.1 - 3.2e-27 94.1 1.1 4e-27 93.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-CCHC PF00098.23 GBG63888.1 - 0.00017 21.5 1.8 0.00017 21.5 1.8 1.8 2 0 0 2 2 2 1 Zinc knuckle F_actin_bind PF08919.10 GBG63888.1 - 0.015 15.4 1.4 0.015 15.4 1.4 2.8 3 1 0 3 3 3 0 F-actin binding DUF2680 PF10925.8 GBG63888.1 - 0.036 14.1 2.7 1.8 8.6 0.2 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2680) Snf7 PF03357.21 GBG63889.1 - 0.32 10.6 15.2 0.61 9.7 6.0 2.9 3 0 0 3 3 3 0 Snf7 CAS_C PF12026.8 GBG63889.1 - 0.51 10.4 4.8 0.97 9.5 4.8 1.4 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Swi5 PF07061.11 GBG63889.1 - 1.8 8.7 14.0 1.2 9.3 2.8 3.8 4 0 0 4 4 4 0 Swi5 DUF5320 PF17253.2 GBG63889.1 - 1.8 9.7 13.1 0.28 12.3 1.5 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5320) LMBR1 PF04791.16 GBG63889.1 - 3.1 6.6 4.4 4.7 6.0 4.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein WRW PF10206.9 GBG63890.1 - 0.0057 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f PRTP PF01366.18 GBG63891.1 - 0.18 9.8 6.0 0.27 9.2 6.0 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein NAM PF02365.15 GBG63892.1 - 1.4e-10 42.1 0.1 2.5e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein Myb_DNA-bind_4 PF13837.6 GBG63895.1 - 0.00042 20.6 3.5 0.00083 19.7 3.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF5408 PF17402.2 GBG63895.1 - 0.76 9.7 1.7 1.3 9.0 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5408) GRP PF07172.11 GBG63895.1 - 0.86 10.3 7.8 3.4 8.4 0.0 2.8 2 1 0 2 2 2 0 Glycine rich protein family DDE_Tnp_4 PF13359.6 GBG63896.1 - 6e-13 48.7 0.0 9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG63896.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG63896.1 - 0.024 15.0 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain ANAPC4_WD40 PF12894.7 GBG63897.1 - 8.9e-06 25.9 0.2 3.2 8.1 0.0 5.7 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GBG63897.1 - 4.6e-05 24.1 2.2 23 6.1 0.1 6.8 7 0 0 7 7 7 1 WD domain, G-beta repeat Myb_DNA-bind_4 PF13837.6 GBG63898.1 - 0.0059 17.0 4.1 0.0059 17.0 4.1 3.1 3 1 1 4 4 4 1 Myb/SANT-like DNA-binding domain DUF1866 PF08952.11 GBG63898.1 - 0.14 12.0 0.8 0.99 9.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RT_RNaseH_2 PF17919.1 GBG63900.1 - 4.1e-24 84.5 0.0 7.3e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63900.1 - 1.2e-20 73.7 0.0 3.8e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG63900.1 - 3.9e-05 24.1 0.0 0.00011 22.7 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63900.1 - 0.00074 20.1 0.0 0.0017 19.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG63900.1 - 0.00076 19.7 0.0 0.0024 18.2 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG63900.1 - 0.004 16.7 0.0 0.0086 15.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG63900.1 - 0.0056 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63902.1 - 0.00027 21.5 0.0 0.00066 20.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63902.1 - 0.002 18.8 0.0 0.0081 16.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG63903.1 - 0.013 15.2 0.3 0.024 14.3 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like gag-asp_proteas PF13975.6 GBG63903.1 - 0.014 16.0 0.5 0.048 14.2 0.4 2.0 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63903.1 - 0.075 13.7 0.4 0.21 12.3 0.1 1.9 2 0 0 2 2 2 0 Aspartyl protease Asp_protease PF09668.10 GBG63903.1 - 0.082 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG63903.1 - 0.087 12.9 2.1 0.16 12.1 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle ZF-HD_dimer PF04770.12 GBG63904.1 - 2.2e-30 104.8 4.3 2.2e-30 104.8 4.3 2.6 4 0 0 4 4 4 1 ZF-HD protein dimerisation region Homeodomain PF00046.29 GBG63904.1 - 0.17 11.7 2.8 0.09 12.6 0.6 1.7 2 0 0 2 2 2 0 Homeodomain SKG6 PF08693.10 GBG63904.1 - 4.6 6.7 7.9 9.8 5.7 7.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sporozoite_P67 PF05642.11 GBG63904.1 - 6.3 4.7 12.1 6.8 4.6 12.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen OmpH PF03938.14 GBG63908.1 - 6.1 7.2 23.2 1.9 8.8 5.0 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CPSase_L_D2 PF02786.17 GBG63909.1 - 2.8e-74 249.2 0.1 2.1e-54 184.2 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GBG63909.1 - 1.2e-41 141.7 0.0 2.3e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GBG63909.1 - 2.6e-37 127.2 0.0 5.4e-37 126.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain RT_RNaseH_2 PF17919.1 GBG63909.1 - 3.8e-34 116.7 0.0 1.5e-20 73.1 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63909.1 - 1.1e-28 99.6 0.0 3.8e-22 78.6 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63909.1 - 2.2e-17 62.9 0.1 5.6e-17 61.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG63909.1 - 3.3e-17 62.9 0.0 2.7e-07 31.2 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG63909.1 - 5.1e-17 61.9 0.0 2e-07 30.8 0.0 2.8 2 0 0 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG63909.1 - 6.8e-14 52.2 0.0 2.5e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG63909.1 - 4.1e-12 46.1 0.3 3.7e-11 43.0 0.1 2.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63909.1 - 1e-08 35.4 0.0 3.1e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG63909.1 - 2.4e-08 33.8 0.0 0.0045 16.8 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG63909.1 - 0.00021 21.6 0.0 0.77 10.1 0.0 3.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain ATP-grasp PF02222.22 GBG63909.1 - 0.0016 18.0 0.0 0.82 9.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain RVP PF00077.20 GBG63909.1 - 0.0031 17.8 0.0 3.3 8.1 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease Dala_Dala_lig_C PF07478.13 GBG63909.1 - 0.015 14.8 0.0 0.056 13.0 0.0 1.8 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus RT_RNaseH_2 PF17919.1 GBG63910.1 - 3.8e-32 110.3 0.0 1e-31 108.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63910.1 - 5.2e-28 97.4 0.1 1.4e-27 96.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63910.1 - 1.3e-18 66.8 0.1 2.6e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG63910.1 - 2.6e-11 43.5 0.3 8e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63910.1 - 4.1e-05 23.7 0.0 0.00021 21.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG63910.1 - 0.0014 18.8 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF4407 PF14362.6 GBG63910.1 - 0.41 10.0 6.1 0.76 9.1 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S64 PF08192.11 GBG63910.1 - 0.42 9.0 2.7 0.65 8.4 2.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 FAM199X PF15814.5 GBG63910.1 - 1.3 8.0 9.5 3.3 6.7 9.5 1.6 1 0 0 1 1 1 0 Protein family FAM199X HAUS6_N PF14661.6 GBG63910.1 - 2.2 7.8 5.2 0.25 10.9 0.4 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus CPSase_L_D2 PF02786.17 GBG63911.1 - 9.1e-43 146.2 0.0 1.4e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 GBG63911.1 - 3.3e-37 126.9 0.0 7.3e-37 125.8 0.0 1.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 GBG63911.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 GBG63912.1 - 3.1e-42 144.5 0.0 5.2e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 GBG63912.1 - 1.2e-36 125.1 0.0 2.7e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain rve PF00665.26 GBG63912.1 - 1.1e-11 44.9 0.0 2.1e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Dala_Dala_lig_C PF07478.13 GBG63912.1 - 0.003 17.1 0.0 0.051 13.1 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus DUF1564 PF07600.11 GBG63912.1 - 0.018 14.7 0.0 0.06 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) PUF PF00806.19 GBG63912.1 - 0.059 13.1 0.6 4.1 7.3 0.0 2.9 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat RT_RNaseH_2 PF17919.1 GBG63913.1 - 3.1e-28 97.7 0.1 6.6e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63913.1 - 4.9e-28 98.1 0.1 1.1e-22 80.7 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63913.1 - 1.1e-25 89.9 1.3 2.4e-25 88.9 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4187 PF13821.6 GBG63913.1 - 0.0052 16.5 2.2 0.013 15.2 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG63913.1 - 0.014 15.7 0.1 0.046 14.0 0.1 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Biotin_carb_N PF00289.22 GBG63914.1 - 1.7e-42 144.4 0.4 6.8e-42 142.5 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain CPSase_L_D2 PF02786.17 GBG63914.1 - 8.8e-32 110.3 0.1 2.2e-31 109.0 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RT_RNaseH_2 PF17919.1 GBG63914.1 - 2.8e-29 101.1 0.0 5.6e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63914.1 - 4.8e-29 100.7 0.3 1.6e-28 99.0 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63914.1 - 0.0056 16.2 0.4 0.013 15.0 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG63914.1 - 0.0068 16.2 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease ATP-grasp PF02222.22 GBG63914.1 - 0.0079 15.8 0.0 0.033 13.8 0.0 2.1 1 0 0 1 1 1 1 ATP-grasp domain Phage_GPO PF05929.11 GBG63914.1 - 0.11 12.1 0.0 0.11 12.1 0.0 3.2 2 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG63915.1 - 3.3e-09 36.7 0.0 9.6e-09 35.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63915.1 - 3e-08 33.5 0.2 0.0061 16.1 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG63915.1 - 0.014 15.6 3.5 0.015 15.5 0.1 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG63915.1 - 0.056 13.7 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-CCCH_6 PF18585.1 GBG63915.1 - 0.077 12.9 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 MerR_2 PF13591.6 GBG63915.1 - 0.14 12.0 0.2 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 MerR HTH family regulatory protein K1377 PF15352.6 GBG63915.1 - 2.3 6.4 5.6 2.9 6.1 2.7 2.0 2 0 0 2 2 2 0 Susceptibility to monomelic amyotrophy DUF4671 PF15710.5 GBG63916.1 - 0.0014 17.6 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4671) Glyco_transf_8 PF01501.20 GBG63917.1 - 5.8e-34 117.8 0.0 8.1e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GBG63917.1 - 0.0025 17.2 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 GBG63917.1 - 0.03 14.3 0.7 0.041 13.8 0.1 1.5 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase DUF5423 PF17461.2 GBG63917.1 - 3.1 6.6 11.5 5.2 5.8 11.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) ABC1 PF03109.16 GBG63920.1 - 3e-29 101.6 0.0 5.1e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GBG63920.1 - 0.00081 19.4 0.4 0.0039 17.2 0.3 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Jagunal PF07086.12 GBG63922.1 - 5.9e-08 33.0 0.1 8.2e-08 32.5 0.1 1.4 1 1 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis ATG7_N PF16420.5 GBG63923.1 - 1.6e-80 270.9 0.0 6.8e-79 265.6 0.0 2.8 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 GBG63923.1 - 6.6e-44 150.1 0.0 1.7e-43 148.8 0.0 1.6 1 1 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 GBG63923.1 - 0.0071 16.4 0.1 0.024 14.7 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F-box-like PF12937.7 GBG63923.1 - 0.029 14.3 0.0 1.1 9.2 0.1 2.7 2 0 0 2 2 2 0 F-box-like RT_RNaseH_2 PF17919.1 GBG63924.1 - 1e-46 157.0 0.0 9.9e-27 92.9 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63924.1 - 7.7e-34 116.1 0.0 7.5e-24 84.0 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63924.1 - 6.5e-20 71.6 0.1 1.6e-10 40.9 0.0 3.6 3 1 1 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG63924.1 - 4.5e-06 27.2 0.0 1.2e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63924.1 - 4.2e-05 24.0 0.0 9.8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG63924.1 - 5.2e-05 23.0 0.0 9.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG63924.1 - 0.00017 21.8 0.5 0.11 12.8 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG63924.1 - 0.0058 16.4 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3006 PF11213.8 GBG63924.1 - 0.18 12.1 2.3 0.61 10.3 2.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) DUF2407_C PF13373.6 GBG63924.1 - 0.64 10.2 3.2 2.2 8.5 3.2 1.9 1 0 0 1 1 1 0 DUF2407 C-terminal domain RVT_1 PF00078.27 GBG63925.1 - 1.6e-20 73.6 0.1 2.4e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63925.1 - 2.3e-17 62.8 0.0 5.8e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63925.1 - 5.7e-12 45.8 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG63925.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg17 rve PF00665.26 GBG63925.1 - 0.12 12.5 0.1 0.32 11.2 0.0 1.8 1 1 1 2 2 2 0 Integrase core domain RVT_1 PF00078.27 GBG63926.1 - 1.1e-20 74.1 0.1 1.6e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63926.1 - 1.3e-18 66.8 0.0 3e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63926.1 - 4.8e-13 49.3 0.0 9.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG63926.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG63927.1 - 1.3e-29 102.1 0.0 4e-29 100.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63927.1 - 8.8e-26 90.2 2.3 4.6e-25 87.9 0.0 3.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG63927.1 - 2.7e-25 88.1 9.9 2.7e-07 31.2 0.2 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Integrase_H2C2 PF17921.1 GBG63927.1 - 1.5e-18 66.6 0.1 3.1e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63927.1 - 9.5e-16 58.1 0.0 2.8e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain ANAPC4_WD40 PF12894.7 GBG63927.1 - 2.3e-06 27.8 2.6 0.47 10.8 0.0 4.8 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Retrotrans_gag PF03732.17 GBG63927.1 - 1.5e-05 25.2 8.9 0.00051 20.3 0.3 3.7 4 0 0 4 4 4 2 Retrotransposon gag protein eIF2A PF08662.11 GBG63927.1 - 0.0012 18.8 0.0 0.0041 17.0 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A zf-H2C2 PF09337.10 GBG63927.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Usp PF00582.26 GBG63928.1 - 8.5e-26 91.2 0.0 5.5e-16 59.4 0.0 2.1 2 0 0 2 2 2 2 Universal stress protein family LRR_4 PF12799.7 GBG63929.1 - 2e-13 50.3 14.4 0.03 14.7 0.0 8.7 5 3 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG63929.1 - 0.0011 19.2 19.2 3.1 8.7 0.1 8.0 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 GBG63929.1 - 0.002 17.9 23.8 0.91 9.3 0.3 7.6 6 1 3 9 9 9 3 Leucine rich repeat eIF_4EBP PF05456.11 GBG63929.1 - 0.0021 18.0 0.0 0.0021 18.0 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) LRR_6 PF13516.6 GBG63929.1 - 0.0079 16.2 20.5 1.7 8.9 0.0 9.1 11 0 0 11 11 11 1 Leucine Rich repeat Bindin PF02084.15 GBG63930.1 - 6.7 6.9 13.9 6.1 7.0 0.4 2.7 2 0 0 2 2 2 0 Bindin Ribosomal_60s PF00428.19 GBG63930.1 - 9.9 6.8 11.6 0.36 11.4 4.8 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF659 PF04937.15 GBG63931.1 - 6.4e-31 107.3 0.0 9.9e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG63933.1 - 1.9e-50 169.0 0.0 5.6e-25 87.3 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63933.1 - 6.7e-39 132.4 0.0 3.6e-23 81.8 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63933.1 - 8.4e-18 64.2 1.7 1.3e-17 63.6 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain HisKA PF00512.25 GBG63933.1 - 8.1e-17 61.0 0.0 8.1e-17 61.0 0.0 3.4 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain rve PF00665.26 GBG63933.1 - 3.4e-15 56.3 0.0 1.6e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG63933.1 - 8e-12 45.7 0.0 1.6e-05 25.4 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG63933.1 - 8.7e-11 41.7 0.0 8.7e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG63933.1 - 5e-10 39.8 0.0 0.00035 21.1 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease HATPase_c PF02518.26 GBG63933.1 - 2.6e-06 27.9 0.0 0.00012 22.5 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Asp_protease PF09668.10 GBG63933.1 - 2.4e-05 24.1 0.0 0.057 13.2 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease RVT_1 PF00078.27 GBG63933.1 - 0.00043 19.8 0.0 0.046 13.2 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG63933.1 - 0.44 10.8 5.4 2.9 8.2 0.0 4.0 4 0 0 4 4 3 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG63934.1 - 2.6e-40 136.5 0.0 2.7e-21 75.5 0.0 3.1 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63934.1 - 4.1e-29 101.0 0.0 3e-19 69.2 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Response_reg PF00072.24 GBG63934.1 - 5.1e-22 78.2 0.2 1.5e-14 54.1 0.1 4.4 4 0 0 4 4 4 3 Response regulator receiver domain RVT_1 PF00078.27 GBG63934.1 - 2.6e-17 63.1 0.8 4.5e-13 49.2 0.0 3.1 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) HATPase_c PF02518.26 GBG63934.1 - 3.5e-13 50.0 0.1 9.1e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Retrotrans_gag PF03732.17 GBG63934.1 - 0.00011 22.4 1.5 0.56 10.5 0.1 4.5 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG63934.1 - 0.021 14.7 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Fer4_2 PF12797.7 GBG63935.1 - 0.65 10.2 5.4 2.2 8.5 0.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain DUF659 PF04937.15 GBG63936.1 - 1.1e-19 70.8 0.0 3.5e-19 69.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DAGK_cat PF00781.24 GBG63938.1 - 7.2e-30 103.2 0.0 1e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Integrase_H2C2 PF17921.1 GBG63939.1 - 8e-13 48.3 2.1 1.4e-12 47.5 0.0 2.6 4 0 0 4 4 4 1 Integrase zinc binding domain Chromo PF00385.24 GBG63939.1 - 1.4e-11 44.1 0.0 3.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG63939.1 - 1.9e-06 28.1 0.0 5.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63939.1 - 4e-06 26.5 0.0 1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63939.1 - 1.4e-05 25.1 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63939.1 - 0.00018 21.7 0.0 0.0006 20.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63939.1 - 0.0035 17.5 0.1 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG63939.1 - 0.004 17.4 0.1 0.012 15.9 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein FAM86 PF14904.6 GBG63939.1 - 1.2 9.3 4.0 1.2 9.2 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function DUF659 PF04937.15 GBG63940.1 - 2.9e-34 118.1 0.0 6.5e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG63940.1 - 1.4e-12 47.7 0.1 2.5e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG63941.1 - 0.00011 22.5 1.0 0.00034 20.9 1.0 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG63941.1 - 0.031 14.6 0.6 0.031 14.6 0.6 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG63941.1 - 0.41 10.8 4.9 0.11 12.5 0.7 2.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain HemY_N PF07219.13 GBG63942.1 - 0.11 12.8 2.0 0.15 12.3 2.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus CAF1A PF12253.8 GBG63944.1 - 4.5e-24 84.4 5.3 4.5e-24 84.4 5.3 5.1 4 1 0 4 4 4 1 Chromatin assembly factor 1 subunit A MSP1_C PF07462.11 GBG63945.1 - 0.01 14.5 0.6 0.01 14.5 0.6 2.3 3 0 0 3 3 3 0 Merozoite surface protein 1 (MSP1) C-terminus RVT_1 PF00078.27 GBG63946.1 - 1.1e-27 97.1 0.1 1.4e-27 96.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63947.1 - 5.9e-20 71.2 0.0 2.5e-14 53.1 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63947.1 - 9.3e-15 54.5 0.5 2.7e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG63947.1 - 9.3e-13 47.9 0.0 1.6e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG63947.1 - 1.2e-10 41.6 0.0 3.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG63947.1 - 8.9e-08 32.4 0.0 2.2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG63947.1 - 0.008 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Aminotran_5 PF00266.19 GBG63948.1 - 2.6e-32 112.2 0.0 3.4e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V RNase_H2_suC PF08615.11 GBG63949.1 - 2.9e-19 69.6 0.0 4.6e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Chorion_2 PF03964.15 GBG63949.1 - 0.0064 17.3 2.7 0.012 16.5 2.7 1.4 1 0 0 1 1 1 1 Chorion family 2 Hydrolase_6 PF13344.6 GBG63951.1 - 1.8e-30 105.0 0.0 5.3e-30 103.5 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG63951.1 - 3.6e-17 62.2 0.1 1.2e-16 60.5 0.1 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GBG63951.1 - 2.7e-12 47.4 0.0 4.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GBG63951.1 - 3.7e-07 30.4 0.0 0.012 15.7 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Integrase_H2C2 PF17921.1 GBG63954.1 - 1.9e-16 59.9 0.5 1.9e-16 59.9 0.5 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG63954.1 - 4.8e-15 55.7 0.0 1.3e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63954.1 - 5.9e-09 35.9 0.0 1.7e-07 31.2 0.0 2.5 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63954.1 - 6e-07 29.7 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG63954.1 - 0.0005 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribonuc_2-5A PF06479.12 GBG63954.1 - 0.081 13.1 2.2 0.12 12.6 0.8 2.0 2 0 0 2 2 2 0 Ribonuclease 2-5A Syntaxin-6_N PF09177.11 GBG63954.1 - 0.1 13.2 3.8 2 9.0 3.8 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PIEZO PF15917.5 GBG63954.1 - 1.5 8.2 5.5 3.6 7.0 5.5 1.6 1 0 0 1 1 1 0 Piezo DUF1664 PF07889.12 GBG63954.1 - 2.3 8.3 6.7 5.8 7.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Chromo PF00385.24 GBG63955.1 - 0.00041 20.2 0.1 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG63955.1 - 0.0011 19.2 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Bestrophin PF01062.21 GBG63956.1 - 6.8e-09 35.5 0.2 9.8e-09 35.0 0.2 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RT_RNaseH_2 PF17919.1 GBG63957.1 - 5e-34 116.3 0.0 9.8e-34 115.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63957.1 - 1.3e-29 102.5 0.0 3.2e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63957.1 - 3.1e-19 68.8 0.4 7.9e-19 67.5 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG63957.1 - 0.021 15.0 0.1 7.1 6.9 0.0 3.3 3 0 0 3 3 3 0 Integrase core domain zf-H2C2 PF09337.10 GBG63957.1 - 0.032 14.4 0.0 0.13 12.5 0.0 2.2 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 GBG63957.1 - 0.054 13.3 1.1 3 7.7 0.1 2.7 2 0 0 2 2 2 0 Integrase core domain DUF1564 PF07600.11 GBG63957.1 - 0.1 12.3 0.1 0.35 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) CNOT1_HEAT_N PF16419.5 GBG63957.1 - 0.14 11.8 0.1 0.76 9.4 0.0 1.9 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat AMMECR1 PF01871.17 GBG63958.1 - 1.9e-44 151.2 0.0 2.2e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 AMMECR1 PF01871.17 GBG63959.1 - 1.6e-32 112.4 0.0 1.8e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 zf-CCHC PF00098.23 GBG63960.1 - 0.00055 19.9 0.6 0.00096 19.1 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle MRNIP PF15749.5 GBG63960.1 - 0.98 10.2 11.8 4.2 8.1 11.6 2.2 1 1 0 1 1 1 0 MRN-interacting protein Nop14 PF04147.12 GBG63962.1 - 8.1 4.5 32.3 11 4.0 32.3 1.1 1 0 0 1 1 1 0 Nop14-like family ABATE PF07336.11 GBG63963.1 - 1.9 9.2 6.3 3 8.5 2.1 2.6 2 0 0 2 2 2 0 Putative stress-induced transcription regulator RVT_1 PF00078.27 GBG63964.1 - 2.5e-28 99.1 0.1 3.7e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63964.1 - 2.7e-25 88.3 0.0 7.5e-25 86.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63964.1 - 3.1e-23 82.1 0.0 8.5e-23 80.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63964.1 - 1.2e-16 60.6 0.1 2.5e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain ST7 PF04184.12 GBG63964.1 - 0.22 9.9 0.1 0.32 9.4 0.1 1.1 1 0 0 1 1 1 0 ST7 protein RT_RNaseH_2 PF17919.1 GBG63965.1 - 4.1e-35 119.8 0.0 4.3e-16 58.8 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG63965.1 - 1.4e-29 102.8 0.0 2.7e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG63965.1 - 1.2e-21 77.2 0.1 2.4e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG63965.1 - 3e-16 59.6 0.0 1.2e-06 28.7 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63965.1 - 9.5e-15 54.5 0.1 5.7e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain Plant_tran PF04827.14 GBG63965.1 - 1.6e-14 54.0 0.0 3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein rve PF00665.26 GBG63965.1 - 1.9e-13 50.7 0.0 6.3e-13 49.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG63965.1 - 2e-11 43.6 0.0 4.8e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG63965.1 - 3.2e-05 23.7 0.0 6.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63965.1 - 0.00066 20.3 0.0 0.0027 18.3 0.0 2.1 2 0 0 2 2 1 1 Aspartyl protease Asp_protease PF09668.10 GBG63965.1 - 0.0037 17.0 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63965.1 - 0.01 16.4 0.0 0.035 14.7 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease FUSC PF04632.12 GBG63965.1 - 1.3 7.5 11.3 2.2 6.7 11.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.12 GBG63965.1 - 4.4 8.0 7.2 2.6 8.7 3.5 2.6 2 0 0 2 2 2 0 SlyX Myb_DNA-bind_4 PF13837.6 GBG63967.1 - 3.7e-06 27.2 1.0 5.5e-05 23.5 0.4 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG63968.1 - 4.3e-26 90.9 0.0 8e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63968.1 - 1.1e-24 86.8 0.0 2e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63968.1 - 8.8e-16 58.1 0.0 1.4e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Btz PF09405.10 GBG63968.1 - 0.27 11.5 8.8 0.7 10.2 8.8 1.6 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding GCP5-Mod21 PF14609.6 GBG63968.1 - 4.6 5.5 4.8 7.1 4.8 4.8 1.2 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Sugar_tr PF00083.24 GBG63969.1 - 4.8e-82 276.2 25.4 3e-42 145.1 6.0 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GBG63969.1 - 3.2e-21 75.6 50.6 8.9e-20 70.9 44.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GBG63969.1 - 0.68 8.1 4.1 0.38 9.0 1.8 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family COX7C PF02935.16 GBG63969.1 - 1.3 9.3 4.1 0.64 10.3 0.6 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Phage_holin_2_3 PF16080.5 GBG63969.1 - 1.5 8.6 4.1 0.6 9.9 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 gag-asp_proteas PF13975.6 GBG63970.1 - 0.029 14.9 0.1 0.076 13.6 0.1 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG63970.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG63971.1 - 0.00033 20.6 4.8 0.00033 20.6 4.8 2.2 3 0 0 3 3 3 1 Zinc knuckle MLVIN_C PF18697.1 GBG63971.1 - 0.052 13.7 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain zf-CCHC_2 PF13696.6 GBG63971.1 - 0.097 12.5 5.8 0.17 11.8 5.8 1.4 1 0 0 1 1 1 0 Zinc knuckle S-antigen PF05756.11 GBG63971.1 - 2 8.8 4.4 3.5 8.1 4.4 1.3 1 0 0 1 1 1 0 S-antigen protein DUF3169 PF11368.8 GBG63972.1 - 0.4 10.1 0.6 0.67 9.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) RT_RNaseH_2 PF17919.1 GBG63973.1 - 8.9e-21 73.8 0.0 2.1e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63973.1 - 4.9e-20 71.4 0.1 1.2e-19 70.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG63973.1 - 3.6e-12 46.5 0.0 8.9e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63973.1 - 3.5e-08 33.6 0.6 1.2e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG63973.1 - 0.01 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG63973.1 - 0.014 15.6 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger SlyX PF04102.12 GBG63973.1 - 0.016 15.8 0.8 0.016 15.8 0.8 4.5 4 1 1 5 5 5 0 SlyX DUF659 PF04937.15 GBG63974.1 - 5.5e-33 114.0 0.1 9.7e-33 113.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG63974.1 - 3.1e-07 30.9 0.2 4.1e-06 27.3 0.0 2.9 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63974.1 - 0.00011 22.8 0.0 0.00053 20.6 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG63974.1 - 0.00016 21.4 0.2 0.00031 20.5 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Asp_protease PF09668.10 GBG63974.1 - 0.0021 17.9 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63974.1 - 0.049 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG63975.1 - 1.1e-29 102.8 0.6 2.8e-29 101.5 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63975.1 - 2.8e-28 97.9 0.2 1.1e-27 96.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63975.1 - 4.2e-20 71.6 0.2 8.6e-20 70.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain NAP PF00956.18 GBG63975.1 - 5.9e-17 61.7 3.3 1.5e-16 60.4 3.3 1.6 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) rve PF00665.26 GBG63975.1 - 5.8e-15 55.5 0.0 1.7e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG63975.1 - 0.0015 18.7 0.0 0.0039 17.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG63975.1 - 0.02 14.6 0.3 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Peptidase_S64 PF08192.11 GBG63975.1 - 0.32 9.4 3.9 0.63 8.5 3.9 1.4 1 0 0 1 1 1 0 Peptidase family S64 HAUS6_N PF14661.6 GBG63975.1 - 1.9 8.0 6.3 0.4 10.2 0.8 2.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FAM199X PF15814.5 GBG63975.1 - 7.4 5.5 12.5 28 3.6 12.5 2.0 1 0 0 1 1 1 0 Protein family FAM199X rve PF00665.26 GBG63976.1 - 1.2e-05 25.5 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG63976.1 - 0.00014 22.4 0.0 0.00033 21.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63976.1 - 0.00035 21.1 0.0 0.00065 20.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG63976.1 - 0.0069 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 GBG63976.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DUF1758 PF05585.12 GBG63976.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 GBG63977.1 - 5.6e-24 84.1 0.0 1e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63977.1 - 1.2e-19 70.5 0.0 2.3e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63977.1 - 5.7e-10 39.1 0.1 8.6e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG63977.1 - 4.1e-07 30.2 0.1 1.1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG63978.1 - 4.1e-32 111.5 0.1 6.5e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG63978.1 - 2.2e-15 56.5 0.3 1.4e-14 53.9 0.2 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG63978.1 - 5.8e-12 45.9 0.0 1.7e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG63978.1 - 6.9e-12 45.1 0.0 2e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG63978.1 - 0.0024 18.1 0.3 0.0054 16.9 0.3 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF659 PF04937.15 GBG63979.1 - 4.7e-20 72.0 0.0 9.8e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63979.1 - 9e-06 25.4 1.4 2.2e-05 24.2 1.4 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG63979.1 - 0.012 16.1 0.0 0.037 14.6 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63979.1 - 0.029 15.0 0.0 0.074 13.7 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Presenilin PF01080.17 GBG63980.1 - 0.44 9.3 4.8 0.47 9.2 4.8 1.2 1 0 0 1 1 1 0 Presenilin Cob_adeno_trans PF01923.18 GBG63980.1 - 1.4 9.0 8.7 1.8 8.6 0.4 2.2 2 0 0 2 2 2 0 Cobalamin adenosyltransferase NPAT_C PF15712.5 GBG63980.1 - 1.6 7.3 10.0 2 7.0 10.0 1.1 1 0 0 1 1 1 0 NPAT C terminus PIEZO PF15917.5 GBG63980.1 - 2.5 7.5 21.2 1.4 8.4 19.3 1.5 1 1 1 2 2 2 0 Piezo Cellulose_synt PF03552.14 GBG63980.1 - 5 5.5 5.9 6.6 5.1 5.9 1.1 1 0 0 1 1 1 0 Cellulose synthase Di19_C PF14571.6 GBG63980.1 - 8.2 7.0 0.0 8.2 7.0 0.0 3.0 2 1 0 2 2 2 0 Stress-induced protein Di19, C-terminal RT_RNaseH PF17917.1 GBG63981.1 - 4.8e-18 65.4 0.9 8.5e-18 64.6 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63981.1 - 3.6e-17 62.2 0.1 7.8e-17 61.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG63981.1 - 6.2e-12 45.4 0.1 1.4e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NAP PF00956.18 GBG63981.1 - 8.3e-09 35.0 0.0 2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) zf-H2C2 PF09337.10 GBG63981.1 - 0.0015 18.7 0.0 0.02 15.1 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger Thioredoxin_11 PF18078.1 GBG63981.1 - 0.015 15.4 0.6 0.89 9.7 0.2 2.4 2 0 0 2 2 2 0 Thioredoxin-like SNTX domain rve PF00665.26 GBG63982.1 - 3e-10 40.3 0.0 6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG63982.1 - 0.00017 21.2 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63983.1 - 4.3e-16 58.8 0.0 1.3e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63983.1 - 1.6e-14 54.1 0.0 3.5e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG63983.1 - 4.2e-11 43.1 0.0 1.4e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG63983.1 - 2.5e-05 23.9 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG63983.1 - 0.00076 20.1 0.0 0.0024 18.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63983.1 - 0.0023 18.5 0.0 0.0065 17.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG63983.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RVP PF00077.20 GBG63983.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG63985.1 - 2.8e-31 108.8 0.0 4.4e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63985.1 - 2.9e-31 107.5 0.0 9.7e-31 105.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63985.1 - 2.8e-30 104.7 0.0 1.1e-29 102.8 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63985.1 - 3.7e-10 39.8 0.0 8.9e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG63985.1 - 9.3e-09 35.5 0.1 4.2e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG63985.1 - 0.0086 16.0 0.6 0.03 14.3 0.6 1.9 1 0 0 1 1 1 1 Zinc knuckle HTH_28 PF13518.6 GBG63985.1 - 0.017 15.2 0.1 0.053 13.7 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 GBG63985.1 - 0.057 13.2 0.2 0.17 11.7 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DUF1564 PF07600.11 GBG63985.1 - 1.2 8.9 3.6 1.8 8.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) EMP24_GP25L PF01105.24 GBG63985.1 - 9.1 6.2 9.8 15 5.5 0.0 3.6 4 0 0 4 4 4 0 emp24/gp25L/p24 family/GOLD RT_RNaseH_2 PF17919.1 GBG63986.1 - 1.4e-27 95.7 0.0 2.9e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63986.1 - 2e-27 95.5 0.3 4.2e-27 94.5 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63986.1 - 1.1e-15 57.9 0.0 2.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG63986.1 - 1.7e-10 40.8 0.9 1.7e-10 40.8 0.9 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG63986.1 - 0.051 13.3 1.5 0.086 12.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) NAP PF00956.18 GBG63987.1 - 5.2e-33 114.4 0.0 5.2e-33 114.4 0.0 2.8 2 0 0 2 2 1 1 Nucleosome assembly protein (NAP) rve PF00665.26 GBG63987.1 - 2.3e-14 53.6 0.0 7.5e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG63987.1 - 4.7e-14 52.4 0.0 7.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG63987.1 - 6.9e-12 45.3 0.0 1.9e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG63987.1 - 4.3e-08 33.1 0.0 1.3e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG63987.1 - 3.8e-05 23.9 0.0 0.00018 21.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG63987.1 - 0.0084 16.7 0.0 0.029 14.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG63987.1 - 0.023 14.5 0.0 0.077 12.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RVP PF00077.20 GBG63987.1 - 0.025 14.9 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GBG63987.1 - 0.028 14.2 1.0 0.064 13.1 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 GBG63987.1 - 0.029 15.0 0.1 0.13 12.9 0.1 2.1 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG63987.1 - 0.045 14.0 3.4 0.2 11.9 0.3 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG63988.1 - 6.4e-53 177.5 0.8 1.8e-25 89.2 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG63988.1 - 2.5e-41 139.8 0.1 8.1e-20 70.7 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG63988.1 - 3.7e-14 52.6 1.0 7.3e-14 51.6 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG63988.1 - 3.9e-14 52.8 0.4 6.1e-12 45.8 0.2 2.7 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG63988.1 - 0.026 14.0 0.1 0.13 11.8 0.0 2.0 1 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) STI1 PF17830.1 GBG63988.1 - 0.076 13.0 0.1 0.82 9.7 0.0 2.7 2 0 0 2 2 2 0 STI1 domain EFP PF01132.20 GBG63988.1 - 0.15 12.1 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain MULE PF10551.9 GBG63988.1 - 0.19 12.2 0.3 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 MULE transposase domain RVP_2 PF08284.11 GBG63989.1 - 2.3e-07 30.7 0.0 4.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG63989.1 - 8.5e-07 29.5 0.3 3.3e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG63989.1 - 0.00016 22.2 0.7 0.00053 20.5 0.0 2.3 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG63989.1 - 0.0062 16.3 0.0 0.0062 16.3 0.0 2.1 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG63989.1 - 0.084 12.7 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease Sporozoite_P67 PF05642.11 GBG63989.1 - 3 5.8 8.9 5.9 4.8 8.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ANAPC9 PF12856.7 GBG63990.1 - 0.11 12.7 0.6 5 7.3 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 HCMVantigenic_N PF12154.8 GBG63990.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV DUF659 PF04937.15 GBG63991.1 - 4.9e-25 88.2 0.1 8.6e-25 87.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG63991.1 - 2.6e-05 23.9 0.1 5.2e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2065 PF09838.9 GBG63991.1 - 0.27 11.3 0.3 0.78 9.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Nop53 PF07767.11 GBG63992.1 - 0.34 10.3 2.8 0.42 10.0 2.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) rve PF00665.26 GBG63993.1 - 7.2e-08 32.6 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG63993.1 - 0.00058 20.4 0.0 0.0017 18.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63993.1 - 0.0054 17.4 0.0 0.015 15.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG63993.1 - 0.0062 16.8 0.3 0.048 13.9 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein RVP PF00077.20 GBG63993.1 - 0.014 15.7 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease rve_3 PF13683.6 GBG63993.1 - 0.022 14.5 0.0 0.075 12.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Asp_protease PF09668.10 GBG63993.1 - 0.053 13.3 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease Pro-rich PF15240.6 GBG63993.1 - 4.5 7.5 8.9 0.19 12.0 2.5 1.8 2 0 0 2 2 2 0 Proline-rich RVT_1 PF00078.27 GBG63994.1 - 2.5e-30 105.7 0.0 3.8e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63994.1 - 3.9e-23 81.4 0.0 7.6e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG63994.1 - 7.8e-13 48.7 0.0 1.6e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG63994.1 - 3.6e-10 40.1 0.0 6.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG63994.1 - 0.025 14.0 84.9 0.014 14.8 26.1 3.3 3 0 0 3 3 3 0 SDA1 zf-CCHC_4 PF14392.6 GBG63994.1 - 0.1 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG63994.1 - 0.29 11.3 4.1 0.68 10.1 4.1 1.7 1 0 0 1 1 1 0 Zinc knuckle AIF-MLS PF14962.6 GBG63998.1 - 5.2 7.0 10.4 1.9 8.4 6.5 2.0 2 0 0 2 2 2 0 Mitochondria Localisation Sequence RVT_1 PF00078.27 GBG63999.1 - 2.4e-26 92.6 0.3 3.5e-26 92.1 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG63999.1 - 3.8e-08 33.3 0.0 1.8e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG63999.1 - 7.9e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG63999.1 - 0.00011 22.6 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG63999.1 - 0.00037 21.1 0.0 0.00075 20.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG63999.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease APG17 PF04108.12 GBG63999.1 - 0.064 12.4 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Asp_protease_2 PF13650.6 GBG64000.1 - 3.7e-09 37.1 0.0 3e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG64000.1 - 3.7e-08 33.2 0.0 8.9e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64000.1 - 6.3e-07 29.9 0.0 2.5e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64000.1 - 0.0048 16.7 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease IHO1 PF15771.5 GBG64000.1 - 0.18 10.5 1.6 0.25 10.1 1.6 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 RVT_1 PF00078.27 GBG64001.1 - 1.7e-16 60.4 0.0 3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG64001.1 - 2.1e-07 31.5 0.0 1.4e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64001.1 - 2e-06 28.2 0.1 3.8e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64001.1 - 0.046 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG64001.1 - 0.07 13.4 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG64001.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG64002.1 - 1.2e-16 61.0 0.0 2.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG64002.1 - 0.00088 19.2 2.6 0.0018 18.2 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG64002.1 - 0.044 14.1 0.1 0.14 12.5 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein K_oxygenase PF13434.6 GBG64003.1 - 0.0011 18.1 0.3 0.0015 17.7 0.3 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) rve PF00665.26 GBG64004.1 - 9.5e-12 45.2 0.0 2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG64004.1 - 6.3e-08 32.9 0.0 8.3e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64004.1 - 3e-06 27.2 0.0 7.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG64004.1 - 0.01 16.4 0.0 0.026 15.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG64004.1 - 0.012 15.3 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG64004.1 - 0.044 14.1 0.0 0.23 11.8 0.0 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 GBG64004.1 - 0.056 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG64005.1 - 0.018 15.3 0.1 0.078 13.3 0.0 1.9 1 1 1 2 2 2 0 Retrotransposon gag protein DUF3804 PF12707.7 GBG64005.1 - 0.076 12.8 0.7 4.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3804) rve PF00665.26 GBG64006.1 - 5.7e-16 58.8 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG64006.1 - 7.3e-13 48.4 0.1 3.3e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 GBG64006.1 - 0.0087 15.8 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain 2-oxoacid_dh PF00198.23 GBG64008.1 - 7.4e-78 261.2 0.1 9.3e-78 260.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GBG64008.1 - 1.6e-16 59.9 4.3 2.9e-16 59.1 4.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GBG64008.1 - 0.0019 18.0 1.6 0.29 11.0 0.2 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 GBG64008.1 - 0.0044 17.7 1.6 0.93 10.2 0.2 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 GBG64008.1 - 0.0064 16.4 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 GBG64008.1 - 0.069 12.4 0.2 0.15 11.3 0.2 1.5 1 1 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 GBG64008.1 - 0.11 12.4 0.3 0.33 10.9 0.3 1.8 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain NinG PF05766.12 GBG64009.1 - 0.63 9.9 10.2 1.3 8.9 10.2 1.5 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF2362 PF10154.9 GBG64009.1 - 1.3 7.9 4.9 1.7 7.5 4.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Borrelia_P83 PF05262.11 GBG64009.1 - 2.8 6.3 16.8 3 6.2 16.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RT_RNaseH_2 PF17919.1 GBG64011.1 - 2.6e-25 88.3 0.0 4.9e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64011.1 - 4.2e-23 81.6 0.0 4.1e-22 78.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG64011.1 - 0.012 15.8 0.1 0.16 12.2 0.0 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein alpha-hel2 PF14456.6 GBG64011.1 - 0.022 14.1 0.1 0.049 12.9 0.1 1.5 1 0 0 1 1 1 0 Alpha-helical domain 2 Integrase_H2C2 PF17921.1 GBG64012.1 - 2.2e-13 50.1 0.1 5.2e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG64012.1 - 0.0022 18.2 0.1 0.0048 17.1 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger NOGCT PF08155.11 GBG64012.1 - 0.04 13.9 0.3 0.18 11.8 0.3 2.1 1 0 0 1 1 1 0 NOGCT (NUC087) domain DUF3969 PF13108.6 GBG64012.1 - 0.12 12.4 0.0 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) BUD22 PF09073.10 GBG64012.1 - 6.5 6.0 11.6 13 5.0 11.6 1.4 1 0 0 1 1 1 0 BUD22 Filament PF00038.21 GBG64013.1 - 0.0051 16.4 18.2 0.078 12.5 5.6 4.2 4 0 0 4 4 4 2 Intermediate filament protein DUF4200 PF13863.6 GBG64013.1 - 0.009 16.4 6.1 0.009 16.4 6.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) FlxA PF14282.6 GBG64013.1 - 0.87 9.6 10.1 1.6 8.8 0.3 3.2 3 0 0 3 3 3 0 FlxA-like protein LPP PF04728.13 GBG64013.1 - 3 8.3 9.5 0.74 10.3 0.3 3.3 3 0 0 3 3 3 0 Lipoprotein leucine-zipper HOOK PF05622.12 GBG64013.1 - 4.3 5.4 11.9 1.4 7.0 0.2 2.6 3 0 0 3 3 3 0 HOOK protein DUF5595 PF18077.1 GBG64013.1 - 5.3 7.2 6.4 26 5.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) DUF4140 PF13600.6 GBG64013.1 - 6.3 7.3 11.4 1.4 9.4 0.7 4.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) RVP_2 PF08284.11 GBG64014.1 - 2.1e-09 37.3 0.0 4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG64014.1 - 3.5e-08 33.2 0.0 6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG64014.1 - 0.00032 21.3 0.0 0.00077 20.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64014.1 - 0.00069 20.1 0.0 0.0017 18.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64014.1 - 0.025 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.12 GBG64014.1 - 0.059 14.0 0.3 0.059 14.0 0.3 3.8 4 0 0 4 4 4 0 SlyX Matrilin_ccoil PF10393.9 GBG64014.1 - 0.09 12.6 1.0 31 4.5 0.1 3.9 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Trimer_CC PF08954.11 GBG64014.1 - 0.1 12.2 4.6 3.8 7.1 0.2 3.4 3 0 0 3 3 3 0 Trimerisation motif TolA_bind_tri PF16331.5 GBG64014.1 - 0.91 9.6 10.1 5.9 7.1 0.3 3.1 3 0 0 3 3 3 0 TolA binding protein trimerisation RT_RNaseH_2 PF17919.1 GBG64016.1 - 1.6e-33 114.7 0.0 4.4e-33 113.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64016.1 - 4.7e-28 97.5 0.0 1.7e-27 95.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64016.1 - 1.3e-27 96.8 0.0 2.2e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64016.1 - 3.7e-18 65.4 0.1 8.3e-18 64.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64016.1 - 6.2e-17 61.9 0.0 1.4e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG64016.1 - 0.14 11.8 0.0 0.78 9.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) APG6_N PF17675.1 GBG64016.1 - 3.9 8.0 6.2 0.64 10.6 0.8 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Enolase_like_N PF18374.1 GBG64017.1 - 0.12 11.7 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Enolase N-terminal domain-like RVT_1 PF00078.27 GBG64018.1 - 5.8e-26 91.4 0.0 1.9e-25 89.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64018.1 - 3.8e-25 87.8 0.0 1.4e-24 86.0 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64018.1 - 8.7e-23 80.6 0.0 2.7e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64018.1 - 1.8e-17 63.2 0.1 5.8e-17 61.5 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG64018.1 - 9.7e-06 26.1 0.0 2.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64018.1 - 3.3e-05 24.3 0.0 9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64018.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG64018.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease HIP1_clath_bdg PF16515.5 GBG64018.1 - 0.014 16.0 6.9 0.014 16.0 6.9 3.5 4 0 0 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Retrotrans_gag PF03732.17 GBG64018.1 - 0.017 15.4 3.7 0.54 10.6 0.0 3.7 3 0 0 3 3 3 0 Retrotransposon gag protein Chromo PF00385.24 GBG64018.1 - 0.023 14.6 0.0 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Snapin_Pallidin PF14712.6 GBG64018.1 - 0.23 11.9 6.5 1.1 9.7 1.8 3.0 2 0 0 2 2 2 0 Snapin/Pallidin RT_RNaseH_2 PF17919.1 GBG64019.1 - 2.3e-58 194.4 0.0 4.5e-32 110.1 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64019.1 - 2.8e-53 178.6 0.4 5.1e-27 94.2 0.2 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64019.1 - 8.4e-40 134.7 1.3 3.1e-19 68.8 0.1 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG64019.1 - 1.2e-34 119.8 0.0 5.8e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG64019.1 - 2.2e-23 82.6 0.0 3.8e-06 27.4 0.0 4.1 3 0 0 3 3 3 3 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64019.1 - 1.7e-20 73.5 0.0 1.4e-07 32.0 0.0 3.9 4 0 0 4 4 3 3 Aspartyl protease rve PF00665.26 GBG64019.1 - 5.1e-16 58.9 0.0 5.6e-08 33.0 0.0 3.2 2 0 0 2 2 2 2 Integrase core domain Asp_protease PF09668.10 GBG64019.1 - 5.1e-11 42.4 0.3 0.0094 15.7 0.0 3.6 3 0 0 3 3 3 3 Aspartyl protease RVP_2 PF08284.11 GBG64019.1 - 1.4e-10 41.0 0.0 5e-07 29.5 0.0 3.0 3 0 0 3 3 3 2 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG64019.1 - 6.1e-07 29.6 0.0 0.0083 16.3 0.0 2.9 2 0 0 2 2 2 2 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG64019.1 - 1.2e-05 25.5 1.7 0.0046 17.2 0.0 4.1 4 0 0 4 4 3 1 Retrotransposon gag protein DUF1758 PF05585.12 GBG64019.1 - 5.5e-05 23.0 0.8 0.073 12.8 0.0 3.9 4 0 0 4 4 4 1 Putative peptidase (DUF1758) RVP PF00077.20 GBG64019.1 - 0.00043 20.5 0.0 1.8 8.9 0.0 3.1 2 0 0 2 2 2 2 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG64020.1 - 2.9e-30 104.3 0.0 8.8e-17 61.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64020.1 - 1.6e-25 89.4 0.0 5.7e-25 87.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64020.1 - 1.9e-14 53.5 2.2 4.8e-14 52.2 2.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64020.1 - 2.5e-09 37.4 0.0 5.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG64020.1 - 3.7e-08 33.2 0.2 6.3e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG64020.1 - 0.035 14.3 0.2 0.11 12.7 0.2 2.0 1 0 0 1 1 1 0 H2C2 zinc finger DUF3824 PF12868.7 GBG64020.1 - 3.3 8.4 7.0 9.9 6.8 7.0 1.7 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Retrotrans_gag PF03732.17 GBG64021.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG64022.1 - 1.2e-32 113.2 0.0 2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64022.1 - 8.9e-08 32.1 0.1 2.6e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64022.1 - 2.9e-07 30.3 0.0 5.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64022.1 - 4.4e-05 24.1 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64022.1 - 0.00033 21.2 0.0 0.00089 19.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG64022.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG64022.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG64023.1 - 9.3e-30 103.8 0.0 2.1e-29 102.6 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GBP PF02263.19 GBG64023.1 - 9.6e-21 74.2 0.0 3.1e-18 66.0 0.0 2.7 3 0 0 3 3 3 1 Guanylate-binding protein, N-terminal domain Asp_protease_2 PF13650.6 GBG64023.1 - 4.7e-07 30.4 0.0 1.4e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64023.1 - 2.4e-06 28.0 0.0 7.1e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64023.1 - 4.7e-06 26.4 0.0 9.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64023.1 - 0.00044 20.0 0.0 0.0011 18.7 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG64023.1 - 0.0017 18.6 2.9 0.009 16.3 0.0 3.6 4 0 0 4 4 4 1 Retrotransposon gag protein NPR3 PF03666.13 GBG64023.1 - 0.0029 16.5 17.5 0.0061 15.4 17.5 1.4 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 rve PF00665.26 GBG64023.1 - 0.09 13.0 0.5 0.58 10.4 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain SpoIIIAH PF12685.7 GBG64023.1 - 0.79 9.5 13.8 0.2 11.5 8.3 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein RP-C_C PF11800.8 GBG64023.1 - 1.3 9.0 8.6 0.062 13.4 1.1 2.6 3 0 0 3 3 3 0 Replication protein C C-terminal region MDM10 PF12519.8 GBG64023.1 - 3.1 6.6 10.2 6.3 5.6 10.2 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Sec62 PF03839.16 GBG64023.1 - 4.4 6.8 26.7 0.0038 16.8 13.4 2.5 3 0 0 3 3 3 0 Translocation protein Sec62 Presenilin PF01080.17 GBG64023.1 - 4.6 5.9 20.4 0.22 10.3 12.4 2.1 2 0 0 2 2 2 0 Presenilin DDHD PF02862.17 GBG64023.1 - 5.4 7.1 10.9 1 9.4 5.7 2.3 2 0 0 2 2 2 0 DDHD domain FAM60A PF15396.6 GBG64023.1 - 7 6.6 22.1 0.3 11.1 15.4 2.0 2 0 0 2 2 2 0 Protein Family FAM60A Menin PF05053.13 GBG64025.1 - 0.24 9.7 0.2 0.44 8.9 0.2 1.3 1 0 0 1 1 1 0 Menin RT_RNaseH_2 PF17919.1 GBG64026.1 - 7.6e-28 96.5 0.0 1.5e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64026.1 - 6e-25 87.6 0.0 1.2e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64026.1 - 1e-15 57.6 0.1 2.1e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG64026.1 - 2.8e-14 53.2 0.0 5.6e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V_ATPase_I PF01496.19 GBG64027.1 - 6.4 4.6 11.5 7.4 4.3 11.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Retrotrans_gag PF03732.17 GBG64028.1 - 0.036 14.3 0.4 0.089 13.1 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein RAP1 PF07218.11 GBG64028.1 - 0.19 10.0 1.7 0.26 9.5 1.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Miga PF10265.9 GBG64028.1 - 0.26 10.2 1.8 0.37 9.7 1.8 1.2 1 0 0 1 1 1 0 Mitoguardin FAM199X PF15814.5 GBG64028.1 - 4.7 6.2 8.6 7.6 5.5 8.6 1.3 1 0 0 1 1 1 0 Protein family FAM199X Retrotrans_gag PF03732.17 GBG64029.1 - 3.7e-05 23.9 0.1 0.00011 22.4 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein FAT PF02259.23 GBG64029.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 FAT domain Senescence_reg PF04520.13 GBG64029.1 - 0.056 14.3 1.8 0.12 13.2 1.8 1.5 1 0 0 1 1 1 0 Senescence regulator RVT_1 PF00078.27 GBG64030.1 - 4.3e-28 98.3 0.0 5.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64030.1 - 3.4e-26 91.2 0.0 6.9e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64030.1 - 9.4e-16 58.0 0.0 1.7e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase S6PP_C PF08472.10 GBG64030.1 - 0.0095 15.8 0.0 0.43 10.4 0.0 2.5 1 1 1 2 2 2 1 Sucrose-6-phosphate phosphohydrolase C-terminal zf-CCHC PF00098.23 GBG64031.1 - 9.8e-05 22.3 3.6 0.00017 21.5 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG64031.1 - 0.012 15.5 5.1 0.021 14.7 5.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG64031.1 - 0.37 10.6 2.1 0.75 9.6 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Allexi_40kDa PF05549.11 GBG64031.1 - 1.7 8.1 3.7 2.3 7.6 3.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein ALMT PF11744.8 GBG64031.1 - 3.2 6.5 6.0 3.6 6.3 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RT_RNaseH_2 PF17919.1 GBG64032.1 - 2.7e-12 46.6 0.1 5.6e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64032.1 - 2.2e-11 44.0 0.1 4.9e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64032.1 - 0.0046 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG64034.1 - 1.6e-05 25.1 0.9 0.1 12.9 0.1 2.9 2 0 0 2 2 2 2 Retrotransposon gag protein rve PF00665.26 GBG64035.1 - 9.2e-08 32.3 0.0 1.9e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG64035.1 - 7e-07 29.3 0.0 2.4e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC_4 PF14392.6 GBG64035.1 - 0.08 12.7 1.6 0.18 11.5 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle rve_3 PF13683.6 GBG64035.1 - 0.16 11.7 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain Skp1_POZ PF03931.15 GBG64035.1 - 0.2 11.9 0.2 0.39 10.9 0.2 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF4279 PF14106.6 GBG64036.1 - 0.01 16.1 0.2 4.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) Nucleo_P87 PF07267.11 GBG64036.1 - 3 6.6 7.8 5.7 5.7 7.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RT_RNaseH PF17917.1 GBG64037.1 - 8.3e-22 77.5 0.0 2.3e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64037.1 - 1.7e-20 72.9 0.0 3.4e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64037.1 - 4.1e-06 26.5 0.0 7.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG64038.1 - 1.4e-65 220.9 1.9 8.9e-33 113.7 0.1 3.5 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64038.1 - 4.7e-36 122.8 0.3 2.7e-17 62.6 0.0 3.9 2 1 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64038.1 - 2.5e-34 117.7 6.8 1.6e-21 76.6 0.5 5.1 5 0 0 5 5 5 3 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64038.1 - 1.5e-14 54.2 0.1 7.3e-12 45.5 0.0 2.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG64038.1 - 4.4e-14 52.9 0.1 7.7e-06 26.5 0.0 3.2 3 0 0 3 3 3 2 Aspartyl protease RVP_2 PF08284.11 GBG64038.1 - 1.2e-13 51.0 0.0 1.2e-06 28.4 0.0 3.0 3 0 0 3 3 3 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64038.1 - 1.9e-13 50.8 0.0 2.3e-05 24.9 0.0 4.5 4 0 0 4 4 4 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64038.1 - 1.8e-08 34.2 0.0 0.0031 17.3 0.0 3.7 3 0 0 3 3 3 2 Aspartyl protease Retrotrans_gag PF03732.17 GBG64038.1 - 2.3e-06 27.8 3.6 0.013 15.8 0.1 4.6 5 0 0 5 5 5 2 Retrotransposon gag protein DUF1758 PF05585.12 GBG64038.1 - 0.0024 17.7 0.0 0.0084 15.9 0.0 1.9 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 GBG64038.1 - 0.3 11.2 7.2 3.8 7.7 0.1 3.0 3 0 0 3 3 3 0 Integrase zinc binding domain DUF659 PF04937.15 GBG64040.1 - 5.6e-25 88.0 0.0 1.2e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64040.1 - 8.4e-07 28.7 2.3 2e-06 27.5 2.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SOG2 PF10428.9 GBG64040.1 - 5.9 6.0 40.5 2 7.5 35.1 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein RVT_1 PF00078.27 GBG64042.1 - 1.2e-37 129.6 0.3 1.3e-31 109.8 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64042.1 - 2.7e-18 65.8 0.0 8.4e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64042.1 - 9.1e-07 29.1 0.0 2.9e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG64042.1 - 0.037 14.3 0.7 0.2 11.9 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2058 PF09831.9 GBG64043.1 - 7.2 6.7 15.0 13 5.9 15.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Integrase_H2C2 PF17921.1 GBG64045.1 - 3.3e-15 55.9 2.1 7.8e-15 54.7 0.1 2.6 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG64045.1 - 2.2e-12 47.2 0.0 4.9e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64045.1 - 5.3e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG64045.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG64046.1 - 4.7e-07 29.6 3.7 4.7e-07 29.6 3.7 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG64046.1 - 0.0058 16.4 3.4 0.0058 16.4 3.4 1.8 2 0 0 2 2 2 1 Zinc knuckle DUF1682 PF07946.14 GBG64046.1 - 0.027 13.7 18.8 0.051 12.8 18.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-CCHC_3 PF13917.6 GBG64046.1 - 0.033 14.2 1.7 0.11 12.5 1.7 1.9 1 0 0 1 1 1 0 Zinc knuckle DUF2229 PF09989.9 GBG64046.1 - 1.4 8.5 6.0 2.3 7.8 6.0 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) SmAKAP PF15127.6 GBG64046.1 - 1.9 9.7 10.7 0.61 11.3 6.6 2.3 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein DUF4065 PF13274.6 GBG64046.1 - 2.3 9.1 5.9 4.7 8.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) AAA_23 PF13476.6 GBG64046.1 - 4.2 7.8 12.5 0.81 10.1 8.2 1.8 2 0 0 2 2 2 0 AAA domain MIF4G PF02854.19 GBG64049.1 - 9.2e-54 182.3 2.7 1.3e-53 181.9 2.7 1.2 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 GBG64049.1 - 7.4e-15 54.9 0.2 2.9e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 MA3 domain eIF_4G1 PF12152.8 GBG64049.1 - 0.0082 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Histone PF00125.24 GBG64050.1 - 4.5e-07 30.3 0.6 4.5e-07 30.3 0.6 2.4 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-F_leu_zip PF10473.9 GBG64051.1 - 0.019 15.0 11.7 0.019 15.0 11.7 5.0 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 GBG64051.1 - 2.4 8.4 56.3 81 3.3 18.9 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 GBG64051.1 - 5.8 7.5 63.3 1.1 9.8 25.9 3.9 1 1 2 3 3 3 0 Apg6 coiled-coil region LPP PF04728.13 GBG64051.1 - 6.9 7.1 25.2 1.7 9.1 0.1 6.5 5 1 1 6 6 6 0 Lipoprotein leucine-zipper SOAR PF16533.5 GBG64051.1 - 9.6 6.2 32.5 0.19 11.7 7.8 4.1 2 1 1 3 3 3 0 STIM1 Orai1-activating region V_ATPase_I PF01496.19 GBG64052.1 - 0.2 9.5 3.3 1.4 6.7 0.0 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Myc_N PF01056.18 GBG64052.1 - 0.27 11.1 14.1 0.32 10.8 11.9 2.0 1 1 1 2 2 2 0 Myc amino-terminal region 4HB_MCP_1 PF12729.7 GBG64052.1 - 0.86 9.1 0.0 0.86 9.1 0.0 3.0 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction SAGA-Tad1 PF12767.7 GBG64052.1 - 7.5 6.2 14.1 38 3.9 14.1 2.1 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RT_RNaseH PF17917.1 GBG64053.1 - 2.4e-29 101.7 0.0 1.4e-28 99.2 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64053.1 - 1.4e-28 98.9 0.0 1e-27 96.1 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64053.1 - 1.3e-10 41.5 0.0 1.3e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG64053.1 - 1.7e-06 28.2 2.6 0.015 15.5 0.0 4.5 4 0 0 4 4 4 2 Retrotransposon gag protein RVT_1 PF00078.27 GBG64054.1 - 2.8e-13 49.9 0.1 8.2e-13 48.4 0.0 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG64054.1 - 8.7e-06 25.9 0.0 2.9e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG64054.1 - 0.00016 22.2 0.0 0.00039 20.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64054.1 - 0.00041 20.9 0.0 0.00096 19.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64054.1 - 0.002 17.9 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG64054.1 - 0.066 13.8 9.1 4 8.1 0.0 4.6 4 0 0 4 4 4 0 SlyX Retrotrans_gag PF03732.17 GBG64054.1 - 0.41 11.0 3.7 35 4.8 0.1 3.8 3 0 0 3 3 3 0 Retrotransposon gag protein FlxA PF14282.6 GBG64054.1 - 1.3 9.0 9.1 0.066 13.2 0.5 2.8 2 0 0 2 2 2 0 FlxA-like protein DUF659 PF04937.15 GBG64055.1 - 5.1e-36 123.8 0.2 1.1e-35 122.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG64055.1 - 0.04 14.0 1.4 0.09 12.8 1.4 1.6 1 0 0 1 1 1 0 BED zinc finger RVT_1 PF00078.27 GBG64056.1 - 2.5e-32 112.2 0.7 5e-17 62.2 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64056.1 - 7.9e-20 71.1 0.2 2e-19 69.8 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64056.1 - 3.9e-15 55.7 0.1 2.9e-14 52.9 0.1 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG64056.1 - 1.1e-13 51.0 0.1 2.5e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64056.1 - 2.9e-07 30.3 0.0 5.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF659 PF04937.15 GBG64056.1 - 1.1e-06 28.6 0.0 2.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Asp_protease_2 PF13650.6 GBG64056.1 - 0.0034 18.0 0.0 0.0096 16.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64056.1 - 0.06 13.9 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CDPS PF16715.5 GBG64056.1 - 1.4 8.5 6.0 4 7.0 6.0 1.7 1 0 0 1 1 1 0 Cyclodipeptide synthase Mpp10 PF04006.12 GBG64057.1 - 0.38 9.2 43.4 0.7 8.3 43.4 1.3 1 0 0 1 1 1 0 Mpp10 protein DUF659 PF04937.15 GBG64058.1 - 9.4e-25 87.2 0.0 1.5e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) VIR_N PF15912.5 GBG64058.1 - 2.5 7.6 8.1 6 6.4 8.1 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal Chromo PF00385.24 GBG64059.1 - 5.7e-08 32.5 1.9 1.7e-07 31.0 1.9 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG64060.1 - 3.5e-08 34.0 0.0 1.6e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64060.1 - 1.4e-07 32.0 0.0 1.2e-06 29.0 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64060.1 - 3.8e-07 29.9 0.0 1.1e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Dynamin_N PF00350.23 GBG64060.1 - 6e-06 26.4 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Asp_protease PF09668.10 GBG64060.1 - 6e-05 22.8 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease MMR_HSR1 PF01926.23 GBG64060.1 - 0.0079 16.3 0.1 0.012 15.7 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase CAP160 PF07918.11 GBG64060.1 - 2.8 7.8 10.1 6.7 6.6 1.1 3.6 3 0 0 3 3 3 0 CAP160 repeat RVT_1 PF00078.27 GBG64061.1 - 2.3e-10 40.4 0.0 3.5e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2282 PF10048.9 GBG64062.1 - 0.044 13.8 4.5 27 4.8 0.0 4.4 4 1 0 4 4 4 0 Predicted integral membrane protein (DUF2282) Type_III_YscX PF09474.10 GBG64062.1 - 0.15 12.3 0.0 23 5.3 0.0 2.4 1 1 1 3 3 3 0 Type III secretion system YscX (type_III_YscX) DUF1233 PF06806.12 GBG64063.1 - 0.044 13.4 0.0 8 6.1 0.0 2.8 3 0 0 3 3 3 0 Putative excisionase (DUF1233) RVT_1 PF00078.27 GBG64065.1 - 2.6e-28 99.1 0.2 4e-28 98.5 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64065.1 - 8.8e-22 77.0 0.0 2e-19 69.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Ank_2 PF12796.7 GBG64065.1 - 4e-10 40.1 0.1 9.6e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RT_RNaseH PF17917.1 GBG64065.1 - 4.7e-09 36.5 0.0 1.2e-07 32.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Ank_5 PF13857.6 GBG64065.1 - 9.7e-09 35.3 0.1 3.5e-08 33.5 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GBG64065.1 - 7.8e-08 32.7 0.0 5.5e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GBG64065.1 - 2.2e-05 24.7 0.4 0.00014 22.1 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 GBG64065.1 - 0.0003 21.0 0.0 0.0036 17.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat IceA2 PF05862.11 GBG64065.1 - 0.091 12.7 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein Integrase_H2C2 PF17921.1 GBG64066.1 - 1.3e-13 50.9 0.1 3e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG64066.1 - 3.3e-13 49.8 0.0 7.9e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64066.1 - 1.4e-10 41.1 0.0 3.3e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG64066.1 - 0.22 11.6 9.9 2.1 8.6 4.1 2.6 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG64067.1 - 1.7e-16 60.4 0.0 2.9e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64067.1 - 2.3e-09 37.2 0.0 6.7e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64067.1 - 0.0093 16.2 0.0 0.05 13.9 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase DUF4559 PF15112.6 GBG64067.1 - 0.082 12.6 4.1 0.14 11.8 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF3292 PF11696.8 GBG64067.1 - 0.42 8.9 6.9 0.62 8.4 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF4834 PF16118.5 GBG64067.1 - 2.1 9.4 4.8 4.6 8.3 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RPN2_C PF18004.1 GBG64067.1 - 6.9 6.6 9.0 15 5.5 9.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Asp_protease_2 PF13650.6 GBG64068.1 - 7.1e-07 29.8 0.0 1.7e-06 28.6 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64068.1 - 1.3e-05 25.7 0.0 3.3e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64068.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Ribosomal_S19 PF00203.21 GBG64070.1 - 1e-35 121.5 0.2 1.4e-35 121.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 gag-asp_proteas PF13975.6 GBG64071.1 - 0.00038 21.0 0.0 0.0017 18.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64071.1 - 0.026 15.2 0.0 0.059 14.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease MIase PF02426.16 GBG64071.1 - 0.57 10.4 0.0 0.57 10.4 0.0 3.3 4 0 0 4 4 4 0 Muconolactone delta-isomerase PRTP PF01366.18 GBG64071.1 - 2.3 6.2 5.8 3.7 5.5 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein FGF-BP1 PF06473.12 GBG64071.1 - 6.2 6.6 7.9 0.74 9.6 3.5 1.7 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) RT_RNaseH_2 PF17919.1 GBG64075.1 - 3.9e-37 126.3 0.2 2.8e-19 69.0 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64075.1 - 9.9e-30 103.7 0.0 5.6e-29 101.3 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64075.1 - 1.3e-26 92.9 0.3 2e-19 69.8 0.1 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrin_b_cyt PF08725.11 GBG64075.1 - 0.082 12.6 0.3 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Retrotrans_gag PF03732.17 GBG64075.1 - 0.099 12.9 0.6 2.4 8.5 0.0 3.3 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG64076.1 - 1.4e-30 105.3 0.0 3.2e-30 104.1 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64076.1 - 2.3e-26 92.1 0.0 3.9e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64076.1 - 2.1e-13 50.2 0.0 6.1e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG64076.1 - 8.7e-11 41.7 0.3 1.8e-10 40.7 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG64076.1 - 0.00063 19.9 0.0 0.0017 18.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Sel1 PF08238.12 GBG64079.1 - 3.6e-23 81.5 40.1 2.9e-06 27.8 0.1 11.1 11 2 0 11 11 11 7 Sel1 repeat gag-asp_proteas PF13975.6 GBG64080.1 - 0.00015 22.3 0.6 0.0031 18.0 0.1 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64080.1 - 0.0002 21.9 0.0 0.00064 20.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Tup_N PF08581.10 GBG64080.1 - 0.0022 18.3 1.3 0.0092 16.3 1.3 2.1 1 0 0 1 1 1 1 Tup N-terminal TMF_DNA_bd PF12329.8 GBG64080.1 - 0.0043 17.0 5.1 0.0043 17.0 5.1 3.4 3 0 0 3 3 2 1 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 GBG64080.1 - 0.054 13.6 0.4 0.054 13.6 0.4 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 GBG64080.1 - 0.09 12.6 0.8 0.32 10.8 0.8 1.9 1 0 0 1 1 1 0 Septum formation initiator BLOC1_2 PF10046.9 GBG64080.1 - 0.09 13.1 4.0 0.5 10.7 0.5 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 GBG64080.1 - 0.23 9.4 1.9 0.31 8.9 1.0 1.5 1 1 0 1 1 1 0 Prominin COG2 PF06148.11 GBG64080.1 - 0.56 10.3 7.8 0.18 11.9 2.4 2.8 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HALZ PF02183.18 GBG64080.1 - 0.75 10.1 5.7 0.14 12.4 0.8 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GBG64080.1 - 1.6 8.9 14.7 0.068 13.3 6.8 3.0 3 0 0 3 3 3 0 bZIP transcription factor Cep57_MT_bd PF06657.13 GBG64080.1 - 2.4 8.7 9.9 2.3 8.7 2.8 4.0 3 2 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Nup54 PF13874.6 GBG64080.1 - 7.5 6.6 12.7 0.62 10.2 4.0 2.7 3 0 0 3 3 2 0 Nucleoporin complex subunit 54 Ribosomal_L6 PF00347.23 GBG64081.1 - 1.7e-32 111.9 0.3 3.9e-17 62.7 0.1 2.5 3 0 0 3 3 3 2 Ribosomal protein L6 zf-CCHC PF00098.23 GBG64082.1 - 0.0023 18.0 5.2 0.0023 18.0 5.2 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG64082.1 - 1.2 9.0 7.5 0.34 10.8 3.9 1.8 2 0 0 2 2 2 0 Zinc knuckle KIAA1430 PF13879.6 GBG64082.1 - 8.2 7.2 14.7 2.9e+03 -0.9 14.7 2.9 1 1 0 1 1 1 0 KIAA1430 homologue RT_RNaseH_2 PF17919.1 GBG64083.1 - 8.4e-29 99.6 0.0 2.4e-28 98.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64083.1 - 4.6e-25 87.9 0.0 1e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64083.1 - 3e-22 79.2 0.1 7.3e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dev_Cell_Death PF10539.9 GBG64085.1 - 8.5e-10 38.6 0.1 1.6e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Development and cell death domain RGS12_us2 PF16611.5 GBG64085.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 0 Unstructured region between RBD and GoLoco Cor1 PF04803.12 GBG64085.1 - 0.34 11.1 3.5 0.17 12.1 0.6 1.9 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF4795 PF16043.5 GBG64085.1 - 4.8 6.7 6.7 38 3.8 6.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) RVT_1 PF00078.27 GBG64087.1 - 4.1e-15 55.9 0.2 6.7e-09 35.6 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG64087.1 - 1.3e-07 32.2 0.0 2.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG64087.1 - 4.3e-07 30.1 0.0 1.4e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG64087.1 - 4.6e-06 27.1 0.0 9.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64087.1 - 4.9e-05 23.1 0.0 9.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG64087.1 - 0.0024 17.7 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG64087.1 - 0.026 14.3 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG64088.1 - 9.5e-33 112.2 0.0 4.2e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Kelch_1 PF01344.25 GBG64088.1 - 3.4e-26 90.6 1.4 5.5e-08 32.3 0.0 3.6 3 0 0 3 3 3 3 Kelch motif RT_RNaseH PF17917.1 GBG64088.1 - 8.4e-22 77.5 0.0 2.4e-16 59.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64088.1 - 2.5e-19 69.7 0.0 4.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_6 PF13964.6 GBG64088.1 - 7.7e-14 51.4 0.5 3e-05 24.1 0.0 3.7 1 1 2 3 3 3 3 Kelch motif Kelch_2 PF07646.15 GBG64088.1 - 1e-05 25.3 6.6 0.065 13.2 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 GBG64088.1 - 0.00019 21.3 0.5 0.041 13.9 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 GBG64088.1 - 0.0023 17.9 1.6 0.11 12.5 0.0 3.0 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.6 GBG64088.1 - 0.089 13.1 1.1 3.4 8.1 0.0 2.9 2 1 0 2 2 2 0 Galactose oxidase, central domain Utp14 PF04615.13 GBG64089.1 - 0.025 13.2 0.2 0.028 13.0 0.2 1.1 1 0 0 1 1 1 0 Utp14 protein RVT_1 PF00078.27 GBG64090.1 - 9.8e-31 107.0 0.1 1.4e-30 106.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64090.1 - 1.3e-27 95.7 0.2 2.6e-27 94.8 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64090.1 - 1.9e-14 53.8 0.0 3.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BTRD1 PF17660.1 GBG64090.1 - 0.074 12.9 0.0 8.2 6.3 0.1 3.1 3 0 0 3 3 3 0 Bacterial tandem repeat domain 1 Integrase_H2C2 PF17921.1 GBG64091.1 - 4.5e-19 68.3 0.2 8.6e-19 67.4 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64091.1 - 2.3e-09 37.5 0.2 9e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG64091.1 - 2.3e-07 30.7 0.0 4.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG64091.1 - 3e-07 30.2 0.9 5.6e-07 29.3 0.1 1.9 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG64091.1 - 3.9e-07 30.6 0.0 8.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64091.1 - 3.1e-05 24.5 0.0 6.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG64091.1 - 0.00083 19.2 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RT_RNaseH PF17917.1 GBG64091.1 - 0.0034 17.6 0.1 0.012 15.9 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG64091.1 - 0.0046 16.8 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG64091.1 - 0.014 15.6 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Chromo PF00385.24 GBG64091.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG64092.1 - 0.025 14.8 0.1 0.025 14.8 0.1 3.4 3 2 2 5 5 5 0 Retrotransposon gag protein Inhibitor_I29 PF08246.12 GBG64092.1 - 0.12 12.8 0.1 0.36 11.3 0.1 1.8 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) RVT_1 PF00078.27 GBG64093.1 - 5.6e-29 101.2 0.0 1e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64093.1 - 6.8e-25 87.0 0.0 1.5e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64093.1 - 8.8e-23 80.6 0.0 2.2e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64094.1 - 4.6e-11 42.7 0.1 1.3e-10 41.2 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64094.1 - 2.8e-09 37.2 0.1 6.8e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG64095.1 - 4e-32 111.5 0.0 6.7e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64095.1 - 2.9e-31 107.5 0.0 7.9e-31 106.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64095.1 - 2.1e-29 101.9 0.0 4.7e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64095.1 - 3.4e-05 23.6 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64095.1 - 0.00057 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64095.1 - 0.0061 17.1 0.0 0.017 15.7 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG64095.1 - 0.029 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG64095.1 - 0.11 12.2 0.0 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease Phage_GPO PF05929.11 GBG64095.1 - 0.14 11.7 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG64096.1 - 3.2e-32 111.8 0.0 5.6e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64096.1 - 2.4e-31 107.8 0.0 6.6e-31 106.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64096.1 - 1.8e-29 102.1 0.0 3.9e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64096.1 - 2.7e-05 23.9 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64096.1 - 0.00047 20.7 0.0 0.0012 19.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64096.1 - 0.005 17.4 0.0 0.014 15.9 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG64096.1 - 0.025 14.4 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG64096.1 - 0.09 12.6 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease Phage_GPO PF05929.11 GBG64096.1 - 0.12 11.9 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH PF17917.1 GBG64097.1 - 1.8e-28 98.9 0.0 3.9e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64097.1 - 2.3e-28 98.2 0.0 6.9e-28 96.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64097.1 - 3.9e-25 88.7 0.1 1.8e-22 80.0 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64097.1 - 2.4e-16 59.6 1.5 5.5e-16 58.4 1.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG64097.1 - 8.4e-07 28.8 0.0 2.9e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64097.1 - 8.6e-06 26.3 0.0 2.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG64097.1 - 3e-05 24.2 0.2 0.00016 21.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG64097.1 - 0.00025 21.2 0.1 0.00069 19.8 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG64097.1 - 0.00093 19.7 0.1 0.0037 17.8 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG64097.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG64097.1 - 0.16 11.8 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease Phage_GPO PF05929.11 GBG64097.1 - 4.1 7.0 8.0 0.36 10.4 0.1 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase rve PF00665.26 GBG64098.1 - 1.1e-16 61.1 0.0 2.2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG64098.1 - 0.0024 17.6 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG64099.1 - 1.1e-22 80.0 0.0 1.8e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64099.1 - 7.7e-17 61.5 0.0 1.5e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Kelch_1 PF01344.25 GBG64099.1 - 0.019 14.5 3.0 0.048 13.3 3.0 1.6 1 0 0 1 1 1 0 Kelch motif CMD PF02627.20 GBG64099.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Peptidase_C48 PF02902.19 GBG64100.1 - 5.4e-24 85.2 0.0 1.4e-23 83.9 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 GBG64100.1 - 0.011 15.5 0.3 0.02 14.6 0.3 1.3 1 0 0 1 1 1 0 Adenovirus endoprotease CobN-Mg_chel PF02514.16 GBG64101.1 - 0 1151.9 0.0 0 1151.7 0.0 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 GBG64101.1 - 2.2e-52 177.4 0.4 5e-52 176.3 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) Cytochrom_B562 PF07361.11 GBG64101.1 - 0.059 14.0 0.0 0.86 10.3 0.0 2.7 2 0 0 2 2 2 0 Cytochrome b562 SDA1 PF05285.12 GBG64104.1 - 0.31 10.4 19.4 0.51 9.7 19.4 1.3 1 0 0 1 1 1 0 SDA1 TbpB_B_D PF01298.18 GBG64104.1 - 1.2 9.6 5.1 1.9 8.9 4.5 1.7 1 1 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B CDC45 PF02724.14 GBG64104.1 - 1.7 6.9 15.7 2.5 6.3 15.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG64104.1 - 8.8 4.3 27.6 15 3.5 27.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi RVT_1 PF00078.27 GBG64106.1 - 0.064 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG64107.1 - 0.075 12.9 0.3 0.13 12.1 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG64108.1 - 3.2e-46 155.9 0.0 1.4e-21 76.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64108.1 - 2.2e-41 140.0 0.0 2.8e-19 69.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Jnk-SapK_ap_N PF09744.9 GBG64108.1 - 0.00023 21.4 16.1 0.091 13.0 4.1 2.8 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 PriC PF07445.12 GBG64108.1 - 0.00032 20.7 12.5 0.091 12.7 2.5 2.4 2 0 0 2 2 2 2 Primosomal replication protein priC Drf_GBD PF06371.13 GBG64108.1 - 0.00071 19.2 2.1 1.1 8.8 0.0 3.0 4 0 0 4 4 4 2 Diaphanous GTPase-binding Domain TPR_MLP1_2 PF07926.12 GBG64108.1 - 0.0085 16.2 21.0 0.46 10.6 6.5 2.7 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein COG2 PF06148.11 GBG64108.1 - 0.069 13.2 4.7 5.9 7.0 0.4 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4136 PF13590.6 GBG64108.1 - 0.1 13.2 4.4 8.9 6.9 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4136) HIP1_clath_bdg PF16515.5 GBG64108.1 - 0.11 13.2 14.1 2.9 8.6 3.2 3.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fungal_TACC PF12709.7 GBG64108.1 - 0.15 12.5 0.8 34 5.0 0.1 2.7 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins HMMR_N PF15905.5 GBG64108.1 - 0.2 11.1 7.7 3.5 7.0 0.9 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PAGK PF15284.6 GBG64108.1 - 0.37 10.7 3.1 20 5.2 0.2 2.6 2 0 0 2 2 2 0 Phage-encoded virulence factor Filament PF00038.21 GBG64108.1 - 0.43 10.1 16.5 2.7 7.5 4.3 2.6 2 0 0 2 2 2 0 Intermediate filament protein TMA7 PF09072.10 GBG64108.1 - 1.7 9.5 4.7 51 4.8 0.4 3.2 2 0 0 2 2 2 0 Translation machinery associated TMA7 BST2 PF16716.5 GBG64108.1 - 2 9.1 8.9 15 6.3 1.2 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 RT_RNaseH_2 PF17919.1 GBG64111.1 - 3.1e-08 33.6 0.0 7.7e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG64111.1 - 1.4e-06 28.8 0.0 0.0091 16.6 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG64111.1 - 1.1e-05 25.8 0.0 0.26 11.9 0.0 3.2 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64111.1 - 1.2e-05 25.1 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG64111.1 - 0.0021 17.6 0.1 0.0036 16.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 GBG64111.1 - 0.02 15.2 0.0 0.061 13.6 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG64111.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64112.1 - 2.3e-08 33.9 0.0 1e-07 31.8 0.0 2.0 2 1 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64112.1 - 3.7e-07 30.7 0.0 7.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64112.1 - 7.3e-06 26.5 0.0 1.6e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG64112.1 - 2.8e-05 24.3 0.0 9e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG64112.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG64113.1 - 5.5e-12 45.9 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64113.1 - 2.8e-11 43.3 0.0 5.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MMR_HSR1 PF01926.23 GBG64113.1 - 3.3e-09 36.8 0.0 7.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GBG64113.1 - 0.0014 18.7 1.9 0.018 15.1 0.1 2.9 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.18 GBG64113.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B RVT_1 PF00078.27 GBG64114.1 - 3.5e-27 95.4 0.1 5.5e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64114.1 - 1.7e-24 85.8 0.0 3.2e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64114.1 - 3.6e-23 81.9 0.0 7.1e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64114.1 - 4.8e-06 26.4 0.0 8.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64114.1 - 1.6e-05 25.5 0.0 3.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64114.1 - 1.7e-05 25.3 0.0 3.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64114.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG64115.1 - 2.1e-06 27.9 1.3 0.0065 16.7 0.0 3.9 2 1 1 3 3 3 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG64115.1 - 1.9e-05 24.5 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64115.1 - 2e-05 25.2 0.0 7.3e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64115.1 - 2.5e-05 24.8 0.0 6.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG64115.1 - 5.7e-05 22.7 0.7 0.00011 21.8 0.3 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG64115.1 - 0.028 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease TMF_TATA_bd PF12325.8 GBG64115.1 - 1.3 9.3 10.9 0.45 10.8 0.2 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RVT_1 PF00078.27 GBG64116.1 - 1.3e-32 113.1 0.1 2e-32 112.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG64117.1 - 6.3e-29 101.1 0.1 1.1e-28 100.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64117.1 - 0.00033 20.6 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Polysacc_deac_1 PF01522.21 GBG64117.1 - 0.064 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Polysaccharide deacetylase DDE_Tnp_4 PF13359.6 GBG64118.1 - 7.7e-28 97.1 0.0 1.4e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64118.1 - 4.8e-14 52.4 0.0 7.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG64118.1 - 0.026 14.2 0.1 6.6 6.3 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain RVT_1 PF00078.27 GBG64119.1 - 3.1e-30 105.3 0.2 4.2e-29 101.6 0.0 2.8 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG64119.1 - 1.1e-11 44.9 1.2 0.0094 16.2 0.0 4.1 2 1 1 3 3 3 3 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG64119.1 - 1.6e-06 28.7 0.0 1.3e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG64119.1 - 3.7e-06 26.7 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64119.1 - 0.00058 20.4 0.0 0.0035 17.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease WTX PF09422.10 GBG64119.1 - 0.019 14.0 3.4 0.036 13.1 3.4 1.3 1 0 0 1 1 1 0 WTX protein Asp_protease PF09668.10 GBG64119.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease TolA_bind_tri PF16331.5 GBG64119.1 - 0.11 12.6 3.3 0.36 10.9 3.3 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation Retrotrans_gag PF03732.17 GBG64120.1 - 0.094 13.0 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Myb_DNA-bind_4 PF13837.6 GBG64121.1 - 3.9e-11 43.2 0.7 3.9e-11 43.2 0.7 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG64121.1 - 0.0011 19.2 0.2 0.0028 18.0 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG64121.1 - 0.78 9.9 4.4 0.33 11.1 1.3 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 GBG64122.1 - 1.2e-51 175.6 0.0 1.9e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG64122.1 - 6.1e-37 127.3 0.0 9e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 GBG64122.1 - 3.4e-06 27.2 0.2 6.6e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 GBG64122.1 - 0.00042 19.2 0.0 0.0012 17.7 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Retrotrans_gag PF03732.17 GBG64123.1 - 0.023 14.9 0.6 0.094 13.0 0.2 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein Adeno_terminal PF02459.15 GBG64123.1 - 1.1 7.6 10.9 2.2 6.6 10.9 1.4 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Presenilin PF01080.17 GBG64123.1 - 5.1 5.8 15.9 0.19 10.5 3.4 2.1 2 0 0 2 2 2 0 Presenilin DUF4045 PF13254.6 GBG64123.1 - 9.3 5.8 18.1 3.7 7.1 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) zf-CCHC PF00098.23 GBG64124.1 - 0.055 13.6 0.5 0.11 12.6 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG64125.1 - 1.4e-34 118.1 0.0 2.7e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64125.1 - 7.3e-31 106.6 0.1 1.5e-30 105.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64125.1 - 1.3e-30 106.6 0.1 2.3e-30 105.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64125.1 - 5.4e-19 68.1 0.1 1.1e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64125.1 - 2.8e-13 50.1 0.1 1.3e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Caldesmon PF02029.15 GBG64125.1 - 0.0052 15.6 53.0 0.0091 14.8 53.0 1.3 1 0 0 1 1 1 1 Caldesmon zf-H2C2 PF09337.10 GBG64125.1 - 0.074 13.3 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Peptidase_C97 PF05903.14 GBG64126.1 - 2.6e-43 147.5 0.1 3.7e-43 147.0 0.1 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain RT_RNaseH_2 PF17919.1 GBG64127.1 - 3.5e-23 81.5 0.0 2.5e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64127.1 - 3.1e-21 75.6 0.0 3.1e-20 72.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64127.1 - 1.2e-09 38.4 0.0 2.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG64127.1 - 7.3e-05 22.8 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG64127.1 - 0.041 13.7 0.0 0.16 11.8 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG64128.1 - 2.2e-05 24.7 5.7 0.0088 16.3 0.0 3.8 4 1 1 5 5 5 2 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG64129.1 - 1.7e-28 98.6 0.0 3.7e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64129.1 - 2e-28 98.8 0.0 5e-28 97.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64129.1 - 5.4e-08 32.8 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DNA_pol_phi PF04931.13 GBG64131.1 - 0.36 8.9 13.5 0.36 8.9 13.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG64131.1 - 0.41 8.8 12.9 0.43 8.7 12.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG64131.1 - 0.41 8.9 15.6 0.45 8.7 15.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Drc1-Sld2 PF11719.8 GBG64131.1 - 0.45 10.0 6.4 0.52 9.8 6.4 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Mpp10 PF04006.12 GBG64131.1 - 0.59 8.5 12.5 0.69 8.3 12.5 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC27 PF09507.10 GBG64131.1 - 1.6 8.0 14.4 2 7.7 14.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CPP1-like PF11833.8 GBG64132.1 - 8.8e-52 175.6 0.1 1.9e-51 174.5 0.1 1.6 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like gag-asp_proteas PF13975.6 GBG64135.1 - 6.9e-08 32.9 0.0 1.5e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64135.1 - 8.4e-08 32.8 0.0 1.9e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG64135.1 - 6.4e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64135.1 - 0.0035 17.1 0.0 0.0095 15.7 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease DUF4187 PF13821.6 GBG64135.1 - 0.0036 17.0 0.4 0.0089 15.8 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG64135.1 - 0.029 14.6 0.2 0.029 14.6 0.2 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG64137.1 - 4.1e-20 72.2 0.0 1.2e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64137.1 - 1.5e-16 60.2 0.2 6.5e-16 58.2 0.2 2.2 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG64137.1 - 2.7e-10 40.5 2.2 3.1e-10 40.3 0.2 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG64137.1 - 1.3e-06 29.0 0.0 3.4e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64137.1 - 2.6e-06 27.9 0.0 7.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64137.1 - 8.6e-06 25.6 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG64137.1 - 0.0021 18.1 0.0 0.0084 16.1 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG64137.1 - 0.0032 17.3 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease HIP1_clath_bdg PF16515.5 GBG64137.1 - 0.014 16.0 2.4 0.014 16.0 2.4 3.1 4 0 0 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc29 PF17082.5 GBG64137.1 - 0.084 12.7 3.4 0.072 12.9 0.8 2.2 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF4407 PF14362.6 GBG64137.1 - 0.12 11.7 14.3 0.012 15.0 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RT_RNaseH_2 PF17919.1 GBG64138.1 - 3.2e-25 88.1 0.0 7.8e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64138.1 - 3.3e-23 82.0 0.0 7.6e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG64138.1 - 0.00097 19.4 0.2 0.016 15.5 0.0 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG64138.1 - 0.0019 18.4 0.2 0.014 15.6 0.1 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG64138.1 - 0.005 16.4 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syntaxin-6_N PF09177.11 GBG64138.1 - 0.26 11.8 3.7 9 6.9 0.1 3.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Longin PF13774.6 GBG64138.1 - 0.71 9.9 2.8 1.6 8.8 0.2 2.9 3 1 1 4 4 4 0 Regulated-SNARE-like domain DUF4407 PF14362.6 GBG64138.1 - 0.96 8.7 11.0 1.6 8.0 1.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 GBG64138.1 - 1.2 8.6 8.4 10 5.6 0.2 3.5 3 0 0 3 3 3 0 fzo-like conserved region DUF2497 PF10691.9 GBG64138.1 - 5.5 7.5 6.6 7.8 7.0 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2497) CLZ PF16526.5 GBG64138.1 - 8.4 6.8 12.0 1.8 9.0 0.5 3.5 4 0 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Symplekin_C PF12295.8 GBG64140.1 - 7.1e-11 42.5 0.1 1e-10 42.0 0.1 1.2 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 GBG64141.1 - 1.5e-38 132.7 0.3 2e-37 129.1 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3453) Symplekin_C PF12295.8 GBG64141.1 - 1.9e-37 129.2 0.1 4.1e-37 128.1 0.1 1.6 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal Chloroa_b-bind PF00504.21 GBG64142.1 - 3e-48 164.4 0.0 4.5e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Ribosomal_S27e PF01667.17 GBG64144.1 - 6.9e-29 99.3 5.5 8.6e-29 99.0 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 GBG64144.1 - 0.0092 15.7 1.1 0.015 15.0 1.1 1.4 1 0 0 1 1 1 1 CSL zinc finger DUF3795 PF12675.7 GBG64144.1 - 0.034 14.5 2.0 0.21 12.0 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) zinc_ribbon_12 PF11331.8 GBG64144.1 - 4.5 7.2 9.2 6.4 6.7 5.2 2.7 1 1 0 2 2 2 0 Probable zinc-ribbon domain Retrotrans_gag PF03732.17 GBG64145.1 - 0.012 15.9 0.0 0.047 14.0 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG64146.1 - 5.8e-39 133.9 0.2 6.1e-21 75.0 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) CG-1 PF03859.16 GBG64146.1 - 8.7e-32 109.3 21.5 1e-31 109.1 0.6 3.9 3 0 0 3 3 2 2 CG-1 domain RT_RNaseH_2 PF17919.1 GBG64146.1 - 2.6e-30 104.4 0.0 6.5e-29 99.9 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64146.1 - 2.2e-29 101.8 0.0 1.7e-28 98.9 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64146.1 - 2.5e-09 37.0 0.0 2.1e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease IQ PF00612.27 GBG64146.1 - 2.3e-07 30.0 31.2 0.0004 19.9 0.5 5.7 5 0 0 5 5 5 4 IQ calmodulin-binding motif Retrotrans_gag PF03732.17 GBG64146.1 - 9e-05 22.7 0.2 0.0015 18.8 0.1 5.8 6 0 0 6 6 4 2 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG64146.1 - 0.00011 22.8 0.0 0.00036 21.1 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Ank_2 PF12796.7 GBG64146.1 - 0.00032 21.2 0.1 0.00092 19.8 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) gag-asp_proteas PF13975.6 GBG64146.1 - 0.0054 17.3 0.0 0.02 15.5 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Ank_4 PF13637.6 GBG64146.1 - 0.02 15.5 0.1 0.13 12.8 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF2781 PF10914.8 GBG64146.1 - 0.072 13.5 0.0 0.072 13.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) Ank_3 PF13606.6 GBG64146.1 - 0.15 12.7 0.0 0.61 10.8 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.6 GBG64146.1 - 0.19 12.1 0.1 0.59 10.5 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SAPS PF04499.15 GBG64148.1 - 0.019 13.8 1.4 0.016 14.0 1.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 GBG64148.1 - 0.024 13.0 12.5 0.033 12.5 12.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG64148.1 - 1.3 7.0 40.6 1.9 6.5 40.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG64148.1 - 3.4 5.8 34.2 5.5 5.1 34.2 1.2 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG64149.1 - 9.4e-31 107.0 0.0 1.7e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64149.1 - 3.6e-16 59.0 0.0 7.5e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64149.1 - 0.0003 21.1 0.0 0.00057 20.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG64150.1 - 1.4e-12 47.3 0.0 3.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG64150.1 - 3.8e-12 46.5 0.0 1.4e-11 44.6 0.0 2.0 3 0 0 3 3 3 1 Integrase core domain HECT PF00632.25 GBG64152.1 - 6.9e-46 157.1 0.0 4e-44 151.3 0.0 2.2 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) ubiquitin PF00240.23 GBG64152.1 - 3.8e-16 58.6 0.0 6.9e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GBG64152.1 - 1.7e-06 27.7 0.0 3.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 GBG64152.1 - 0.00076 19.4 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 GBG64152.1 - 0.039 14.4 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Integrase_H2C2 PF17921.1 GBG64153.1 - 3.8e-12 46.1 0.6 9.4e-12 44.9 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG64153.1 - 1.1e-08 34.9 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG64153.1 - 0.00091 19.4 0.0 0.0036 17.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Sec1 PF00995.23 GBG64155.1 - 3.6e-112 376.5 0.6 4.7e-112 376.1 0.6 1.1 1 0 0 1 1 1 1 Sec1 family PGK PF00162.19 GBG64155.1 - 0.00044 19.3 1.2 0.0018 17.3 0.3 2.0 2 0 0 2 2 2 1 Phosphoglycerate kinase Occludin_ELL PF07303.13 GBG64155.1 - 0.042 14.6 0.5 1 10.1 0.1 3.0 3 1 0 3 3 3 0 Occludin homology domain EcoR124_C PF12008.8 GBG64155.1 - 0.065 12.9 0.8 1.2 8.7 0.3 2.2 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal RT_RNaseH_2 PF17919.1 GBG64156.1 - 3.5e-28 97.6 0.0 7.6e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64156.1 - 4.4e-27 95.0 0.1 8.8e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64156.1 - 1.3e-25 89.7 0.0 3.1e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64156.1 - 6.7e-18 65.0 0.0 1.9e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG64156.1 - 1.1e-11 44.6 0.0 3.1e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain STI1 PF17830.1 GBG64156.1 - 0.0041 17.0 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 STI1 domain Sporozoite_P67 PF05642.11 GBG64156.1 - 6.2 4.8 6.0 8.7 4.3 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ClpS PF02617.17 GBG64157.1 - 1.8e-15 56.5 0.0 2.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Ribosomal_S5 PF00333.20 GBG64159.1 - 8.3e-31 105.8 1.1 2e-30 104.6 1.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 GBG64159.1 - 2.9e-24 84.3 0.0 4.8e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain TSR PF18487.1 GBG64159.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Thrombospondin type 1 repeat CDC45 PF02724.14 GBG64161.1 - 0.0015 17.0 16.7 0.0015 17.0 16.7 3.2 2 1 1 3 3 3 1 CDC45-like protein ABC_membrane PF00664.23 GBG64162.1 - 1.7e-101 339.4 31.0 8.9e-51 173.1 12.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GBG64162.1 - 6.2e-73 243.8 0.1 8.1e-36 123.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GBG64162.1 - 3.6e-12 46.2 5.3 0.0032 16.9 0.0 4.3 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GBG64162.1 - 4.8e-09 36.8 0.5 0.0009 19.7 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GBG64162.1 - 2.9e-08 33.3 1.3 0.014 15.1 0.3 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GBG64162.1 - 1.6e-06 28.2 0.1 0.043 13.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 GBG64162.1 - 8.9e-06 25.5 0.5 0.082 12.6 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 GBG64162.1 - 1.4e-05 25.0 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 GBG64162.1 - 3.1e-05 23.3 0.0 0.21 10.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.14 GBG64162.1 - 0.00012 22.0 0.8 3.1 7.8 0.0 4.3 3 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 GBG64162.1 - 0.00031 20.6 0.2 0.28 10.9 0.1 3.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 GBG64162.1 - 0.00037 20.9 3.7 2.4 8.6 0.0 4.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG64162.1 - 0.00059 20.1 1.4 0.8 10.0 0.1 3.4 2 2 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GBG64162.1 - 0.0018 17.8 0.0 2.5 7.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 GBG64162.1 - 0.0019 18.4 5.5 0.75 10.1 0.5 4.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 GBG64162.1 - 0.0028 17.3 0.0 0.6 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 GBG64162.1 - 0.0049 16.1 0.1 0.57 9.3 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_23 PF13476.6 GBG64162.1 - 0.011 16.2 0.3 6.3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 GBG64162.1 - 0.017 15.0 0.5 5.6 6.8 0.1 2.7 3 0 0 3 3 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 GBG64162.1 - 0.022 14.9 0.1 8.7 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GBG64162.1 - 0.022 13.9 0.1 8.1 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 GBG64162.1 - 0.028 15.0 0.1 7.3 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GBG64162.1 - 0.03 14.1 0.4 5.8 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 GBG64162.1 - 0.045 13.8 2.1 3.6 7.6 0.4 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 GBG64162.1 - 0.054 13.2 0.3 1.2 8.9 0.0 2.5 3 0 0 3 3 2 0 Cytidylate kinase MMR_HSR1 PF01926.23 GBG64162.1 - 0.059 13.5 1.8 8.3 6.5 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GBG64162.1 - 0.12 11.7 0.1 6.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Mg_chelatase PF01078.21 GBG64162.1 - 0.16 11.3 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PRK PF00485.18 GBG64162.1 - 0.17 11.6 0.3 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_ATPase PF09818.9 GBG64162.1 - 0.26 10.0 7.4 0.56 9.0 0.1 2.6 3 0 0 3 3 2 0 Predicted ATPase of the ABC class ABA_GPCR PF12430.8 GBG64162.1 - 0.64 9.7 4.7 1.7 8.4 3.2 2.2 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor IstB_IS21 PF01695.17 GBG64162.1 - 0.77 9.5 3.0 35 4.1 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein Mito_carr PF00153.27 GBG64163.1 - 7.7e-55 182.8 4.1 3.7e-19 68.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GBG64163.1 - 0.037 13.2 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Colicin_V PF02674.16 GBG64163.1 - 0.04 13.9 2.0 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Colicin V production protein SipA_VBS PF17985.1 GBG64163.1 - 0.094 12.6 0.1 0.31 11.0 0.1 1.9 1 0 0 1 1 1 0 SipA vinculin binding site SPATIAL PF15256.6 GBG64164.1 - 1.7 8.9 6.5 6.3 7.1 6.5 1.9 1 0 0 1 1 1 0 SPATIAL zf-CCHC_2 PF13696.6 GBG64166.1 - 0.0026 17.5 0.6 0.0044 16.8 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG64166.1 - 0.0056 17.2 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG64166.1 - 0.0064 16.7 1.0 0.041 14.1 0.3 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG64166.1 - 0.009 16.6 0.0 0.02 15.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG64166.1 - 0.019 15.2 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Strep_SA_rep PF06696.11 GBG64166.1 - 0.033 14.2 0.2 0.083 12.9 0.2 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat zf-CCHC PF00098.23 GBG64166.1 - 0.12 12.5 1.9 0.22 11.7 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Sin_N PF04801.13 GBG64167.1 - 0.045 13.0 10.4 0.056 12.7 10.4 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region MAP7 PF05672.11 GBG64167.1 - 0.33 10.6 34.7 0.018 14.7 28.8 1.9 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family SLC12 PF03522.15 GBG64167.1 - 1.2 8.0 9.2 1.8 7.5 9.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF2058 PF09831.9 GBG64167.1 - 1.9 8.6 18.4 0.31 11.2 14.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Connexin PF00029.19 GBG64167.1 - 7.8 6.2 9.1 19 4.9 9.1 1.6 1 0 0 1 1 1 0 Connexin zf-Dof PF02701.15 GBG64168.1 - 1.1e-31 108.8 8.1 2.3e-31 107.7 8.1 1.6 1 0 0 1 1 1 1 Dof domain, zinc finger RT_RNaseH_2 PF17919.1 GBG64169.1 - 3e-23 81.7 0.1 6.7e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64169.1 - 4.3e-17 62.0 0.1 9.9e-17 60.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG64169.1 - 7.5e-13 48.5 0.2 1.4e-12 47.6 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64169.1 - 4.9e-10 39.6 0.0 1.5e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64169.1 - 8.5e-10 38.9 0.1 2.7e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DUF5095 PF17016.5 GBG64169.1 - 0.048 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Pullulanase_Ins PF18494.1 GBG64169.1 - 0.083 13.4 0.1 0.64 10.5 0.1 2.4 2 0 0 2 2 2 0 Pullulanase Ins domain RT_RNaseH_2 PF17919.1 GBG64170.1 - 4.4e-24 84.4 0.0 9.4e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64170.1 - 6.2e-24 84.3 0.0 2.4e-23 82.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64170.1 - 1.4e-08 35.0 0.0 4.2e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG64170.1 - 0.0097 15.7 0.0 0.031 14.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Peptidase_C48 PF02902.19 GBG64172.1 - 8.7e-16 58.4 1.4 2.3e-15 57.0 1.4 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MRP-L28 PF09812.9 GBG64174.1 - 0.00043 20.5 3.5 0.00095 19.3 3.5 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 UBM PF14377.6 GBG64174.1 - 0.095 12.2 0.6 0.19 11.2 0.6 1.5 1 0 0 1 1 1 0 Ubiquitin binding region Transglut_N PF00868.20 GBG64176.1 - 0.044 14.1 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase family Tash_PEST PF07708.11 GBG64178.1 - 8.1 6.7 6.6 0.32 11.2 0.7 1.7 2 0 0 2 2 2 0 Tash protein PEST motif Myb_DNA-bind_4 PF13837.6 GBG64179.1 - 7e-11 42.4 2.1 1.8e-09 37.8 0.6 2.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG64179.1 - 0.018 15.4 0.5 0.061 13.6 0.5 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG64179.1 - 0.065 13.3 0.5 0.18 11.9 0.5 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG64180.1 - 1.2e-26 92.6 0.0 2.9e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64180.1 - 4.9e-20 71.8 0.0 9.8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64180.1 - 6e-08 32.5 0.1 1.5e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64180.1 - 0.043 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Nop14 PF04147.12 GBG64180.1 - 0.15 10.3 21.5 0.21 9.8 21.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG64180.1 - 0.19 10.0 16.9 0.28 9.4 16.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG64180.1 - 0.21 11.0 21.1 0.32 10.4 21.1 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG64180.1 - 1.4 8.2 27.1 2.2 7.5 27.1 1.2 1 0 0 1 1 1 0 BUD22 Afi1 PF07792.12 GBG64180.1 - 7.6 7.0 10.3 18 5.8 10.3 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EPSP_synthase PF00275.20 GBG64182.1 - 1.4e-69 234.9 0.0 2e-45 155.2 0.0 2.1 1 1 1 2 2 2 2 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Coatomer_WDAD PF04053.14 GBG64185.1 - 6.9e-161 536.2 0.0 2.3e-160 534.5 0.0 1.9 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 GBG64185.1 - 1.3e-38 130.2 10.5 2.3e-08 34.6 0.2 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG64185.1 - 1.8e-05 25.0 0.4 7.5 6.9 0.0 5.9 4 2 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 GBG64185.1 - 0.0014 18.6 1.1 0.083 13.1 0.1 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG64185.1 - 0.0042 17.3 2.4 0.24 11.7 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Clathrin PF00637.20 GBG64185.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS Nup160 PF11715.8 GBG64185.1 - 0.083 11.5 3.3 13 4.3 0.0 3.7 3 1 1 4 4 4 0 Nucleoporin Nup120/160 TPR_8 PF13181.6 GBG64185.1 - 0.21 11.9 0.4 2.4 8.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG64185.1 - 1.5 9.9 9.1 6.6 7.8 0.2 4.5 2 1 3 5 5 5 0 Tetratricopeptide repeat DUF4778 PF16008.5 GBG64186.1 - 1.5 8.8 7.5 2 8.4 7.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4778) Pkinase_Tyr PF07714.17 GBG64188.1 - 2.3e-43 148.4 0.0 6.4e-43 146.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG64188.1 - 2.3e-43 148.5 0.0 6e-27 94.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain B_lectin PF01453.24 GBG64188.1 - 2.9e-13 50.2 2.7 5.8e-09 36.4 0.3 3.5 1 1 3 4 4 4 2 D-mannose binding lectin PAN_1 PF00024.26 GBG64188.1 - 5.5e-05 23.0 3.2 0.00012 22.0 3.2 1.5 1 0 0 1 1 1 1 PAN domain Plasmod_Pvs28 PF06247.11 GBG64188.1 - 0.00013 22.1 6.0 0.0004 20.6 6.0 1.8 1 0 0 1 1 1 1 Pvs28 EGF domain APH PF01636.23 GBG64188.1 - 0.00051 20.0 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family PAN_4 PF14295.6 GBG64188.1 - 0.0048 16.8 1.3 0.013 15.4 1.3 1.7 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 GBG64188.1 - 0.0054 16.8 3.7 0.014 15.5 3.7 1.7 1 0 0 1 1 1 1 PAN-like domain SKG6 PF08693.10 GBG64188.1 - 0.98 8.9 5.8 2.1 7.8 5.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RT_RNaseH_2 PF17919.1 GBG64190.1 - 1.6e-33 114.7 0.1 3.7e-33 113.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64190.1 - 1.2e-30 105.8 0.9 2.2e-30 105.1 0.2 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64190.1 - 1e-11 44.8 0.2 1.7e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rab3-GTPase_cat PF13890.6 GBG64190.1 - 0.061 13.0 0.4 0.76 9.4 0.0 2.2 1 1 1 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit REV PF00424.18 GBG64191.1 - 0.0094 16.0 3.6 0.23 11.5 0.1 2.4 2 0 0 2 2 2 2 REV protein (anti-repression trans-activator protein) Bacillus_HBL PF05791.11 GBG64194.1 - 0.002 18.0 1.8 0.0025 17.7 1.8 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) dCache_2 PF08269.11 GBG64194.1 - 0.075 12.2 6.6 0.094 11.9 6.6 1.2 1 0 0 1 1 1 0 Cache domain DUF1664 PF07889.12 GBG64194.1 - 0.17 11.9 2.6 0.3 11.2 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TssO PF17561.2 GBG64194.1 - 0.21 11.7 6.4 0.41 10.7 6.4 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssO ISG65-75 PF11727.8 GBG64194.1 - 0.24 10.6 13.6 0.35 10.1 13.6 1.3 1 1 0 1 1 1 0 Invariant surface glycoprotein FAM76 PF16046.5 GBG64194.1 - 0.3 10.4 13.9 0.33 10.2 13.9 1.0 1 0 0 1 1 1 0 FAM76 protein YtxH PF12732.7 GBG64194.1 - 0.59 10.7 6.4 2.4 8.7 6.4 2.0 1 1 0 1 1 1 0 YtxH-like protein DUF4407 PF14362.6 GBG64194.1 - 0.85 8.9 10.8 1.2 8.5 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GvpL_GvpF PF06386.11 GBG64194.1 - 3.7 7.4 10.7 7.5 6.4 10.7 1.6 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Paramyxo_ncap PF00973.19 GBG64194.1 - 3.7 6.3 8.1 4.3 6.1 8.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Med30 PF11315.8 GBG64194.1 - 4.4 7.5 11.5 31 4.7 11.5 1.9 1 1 0 1 1 1 0 Mediator complex subunit 30 DUF4662 PF15578.6 GBG64194.1 - 6.6 6.4 9.9 7.7 6.2 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) FAM176 PF14851.6 GBG64194.1 - 8.4 6.0 11.6 11 5.6 11.6 1.2 1 0 0 1 1 1 0 FAM176 family Filament PF00038.21 GBG64195.1 - 0.039 13.5 1.8 0.7 9.4 0.0 2.3 2 0 0 2 2 2 0 Intermediate filament protein HTH_30 PF13556.6 GBG64195.1 - 0.1 12.4 0.7 0.71 9.7 0.3 2.3 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Retrotrans_gag PF03732.17 GBG64196.1 - 0.0059 16.9 0.2 0.0059 16.9 0.2 2.3 3 0 0 3 3 3 1 Retrotransposon gag protein IATP PF04568.12 GBG64196.1 - 6.7 7.2 13.3 2.3 8.7 0.3 3.6 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP RT_RNaseH_2 PF17919.1 GBG64197.1 - 1.8e-53 178.7 0.0 1e-29 102.5 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64197.1 - 1.5e-50 169.8 0.1 5.4e-29 100.6 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64197.1 - 2.5e-41 141.6 1.2 2e-30 106.0 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64197.1 - 7.1e-16 58.1 1.3 1.8e-15 56.8 0.4 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG64197.1 - 0.0097 16.1 1.2 0.026 14.8 0.2 2.3 2 0 0 2 2 2 1 H2C2 zinc finger GED PF02212.18 GBG64197.1 - 0.28 11.4 3.3 1.3 9.2 3.3 2.2 1 0 0 1 1 1 0 Dynamin GTPase effector domain Atg14 PF10186.9 GBG64197.1 - 1.3 8.0 12.4 3.6 6.6 12.4 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADP_ribosyl_GH PF03747.14 GBG64197.1 - 1.5 8.5 7.1 1.5 8.5 0.4 3.1 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase RWD PF05773.22 GBG64198.1 - 3.9e-19 69.0 0.0 8.7e-18 64.7 0.0 2.6 1 1 0 1 1 1 1 RWD domain IBR PF01485.21 GBG64198.1 - 7.9e-14 51.6 27.4 1.7e-10 41.0 6.0 4.6 5 1 0 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 GBG64198.1 - 1.1e-06 28.5 4.6 1.1e-06 28.5 4.6 4.5 3 1 1 4 4 4 1 zinc-RING finger domain RVT_1 PF00078.27 GBG64198.1 - 3.1e-06 26.9 0.0 6.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_2 PF13639.6 GBG64198.1 - 0.00014 22.1 5.4 0.00014 22.1 5.4 3.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG64198.1 - 0.00041 20.3 0.8 0.00041 20.3 0.8 3.7 3 1 1 4 4 4 1 RING-type zinc-finger DUF2570 PF10828.8 GBG64198.1 - 2.2 8.2 6.0 19 5.1 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) RVT_1 PF00078.27 GBG64200.1 - 9.6e-25 87.4 0.0 2e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG64200.1 - 0.0089 15.7 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) zinc_ribbon_16 PF17034.5 GBG64200.1 - 0.053 13.7 0.2 0.16 12.2 0.2 1.8 1 0 0 1 1 1 0 Zinc-ribbon like family Retrotrans_gag PF03732.17 GBG64200.1 - 0.088 13.1 0.9 0.38 11.1 0.9 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein CsiD PF08943.10 GBG64200.1 - 0.09 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 CsiD SPX PF03105.19 GBG64200.1 - 0.44 10.4 7.0 0.89 9.4 7.0 1.5 1 0 0 1 1 1 0 SPX domain Prominin PF05478.11 GBG64200.1 - 2.3 6.1 4.5 3.5 5.4 4.5 1.2 1 0 0 1 1 1 0 Prominin Pkinase PF00069.25 GBG64201.1 - 5.9e-65 219.3 0.0 1.2e-41 142.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG64201.1 - 8.7e-29 100.6 0.2 2.6e-21 76.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 GBG64201.1 - 1.9e-05 25.3 0.1 4.1e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 GBG64201.1 - 0.0065 16.4 0.2 1 9.3 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GBG64201.1 - 0.024 14.0 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 GBG64201.1 - 0.026 13.5 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 GBG64201.1 - 0.03 13.4 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 GBG64201.1 - 0.15 11.0 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Retrotrans_gag PF03732.17 GBG64202.1 - 0.02 15.2 0.6 0.21 11.9 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein HAUS6_N PF14661.6 GBG64202.1 - 0.95 9.0 4.7 0.44 10.1 0.2 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.15 GBG64202.1 - 2 8.2 5.5 1.9 8.3 1.8 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 GBG64202.1 - 2.3 7.5 10.5 0.43 9.9 6.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Miga PF10265.9 GBG64202.1 - 4.4 6.2 6.3 6.9 5.5 6.3 1.2 1 0 0 1 1 1 0 Mitoguardin DUF1690 PF07956.11 GBG64202.1 - 9.9 6.6 8.3 2.1 8.8 1.8 2.6 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) RVT_1 PF00078.27 GBG64203.1 - 2.4e-32 112.3 0.1 4.4e-32 111.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64203.1 - 1.1e-29 102.3 0.1 3e-29 101.0 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64203.1 - 8.9e-26 90.2 0.3 1.7e-25 89.3 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64203.1 - 7.4e-18 64.4 0.1 1.9e-17 63.1 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64203.1 - 0.00076 19.7 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64203.1 - 0.025 14.8 0.0 0.098 12.9 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger ADIP PF11559.8 GBG64204.1 - 0.00074 19.6 22.9 0.0033 17.5 8.9 2.6 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding Perilipin PF03036.16 GBG64204.1 - 0.0039 16.3 6.2 0.0056 15.8 6.2 1.2 1 0 0 1 1 1 1 Perilipin family DUF4407 PF14362.6 GBG64204.1 - 0.039 13.3 17.5 0.071 12.5 7.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mfp-3 PF04202.13 GBG64204.1 - 0.48 10.8 15.2 0.72 10.3 15.2 1.3 1 0 0 1 1 1 0 Foot protein 3 HALZ PF02183.18 GBG64204.1 - 0.81 10.0 24.3 22 5.3 0.1 5.9 5 1 1 6 6 6 0 Homeobox associated leucine zipper PHM7_cyt PF14703.6 GBG64204.1 - 1.3 9.2 13.0 2.1 8.5 10.7 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter FlaC_arch PF05377.11 GBG64204.1 - 1.6 9.2 7.7 12 6.4 0.1 3.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) RVT_1 PF00078.27 GBG64205.1 - 1.2e-35 123.1 0.1 2e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64205.1 - 1.8e-31 108.2 0.0 4.4e-31 106.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64205.1 - 8.1e-31 106.4 0.0 1.6e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64205.1 - 2.4e-07 30.6 0.0 4.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64205.1 - 1.5e-05 25.6 0.0 3.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64205.1 - 0.00042 20.8 0.0 0.0012 19.3 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG64205.1 - 0.006 16.4 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG64205.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Asp_protease PF09668.10 GBG64205.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease DEK_C PF08766.11 GBG64207.1 - 0.017 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain DUF659 PF04937.15 GBG64208.1 - 1.3e-10 41.3 0.3 6.2e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64208.1 - 6.2e-10 38.7 0.4 4.4e-09 36.0 0.0 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.17 GBG64208.1 - 0.002 18.3 1.9 0.0052 17.0 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Lipin_mid PF16876.5 GBG64208.1 - 0.1 12.7 0.0 0.43 10.7 0.0 2.1 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain rve PF00665.26 GBG64210.1 - 3.8e-05 23.9 0.0 7.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain TPR_4 PF07721.14 GBG64211.1 - 0.034 14.8 2.4 5.9 7.8 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DIL PF01843.19 GBG64212.1 - 4.4e-05 23.7 0.0 0.00034 20.9 0.0 2.3 2 1 0 2 2 2 1 DIL domain DDE_Tnp_4 PF13359.6 GBG64214.1 - 7.1e-30 103.8 0.2 6.9e-29 100.6 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64214.1 - 3.1e-16 59.6 0.0 5.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG64214.1 - 0.039 13.6 0.2 5.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Transposase DDE domain PolyA_pol_RNAbd PF12627.7 GBG64215.1 - 7.9e-05 22.3 0.2 0.0002 21.0 0.2 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A GREB1 PF15782.5 GBG64215.1 - 1.8 5.6 9.9 2.2 5.3 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 GBG64215.1 - 2.2 7.8 13.1 3 7.4 13.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hamartin PF04388.12 GBG64215.1 - 2.2 6.8 6.5 2.7 6.5 6.5 1.1 1 0 0 1 1 1 0 Hamartin protein Lin-8 PF03353.15 GBG64215.1 - 5.1 6.6 8.9 8 5.9 8.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PolyA_pol PF01743.20 GBG64216.1 - 3.6e-11 43.6 0.0 1e-10 42.1 0.0 1.7 1 1 0 1 1 1 1 Poly A polymerase head domain zf-CCHC PF00098.23 GBG64218.1 - 0.036 14.1 1.5 0.064 13.4 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG64219.1 - 1.4e-23 83.2 0.0 2.8e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64219.1 - 1.6e-23 82.6 0.0 2.9e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64219.1 - 2.7e-11 43.4 0.5 1.6e-10 40.9 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG64219.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 PolyA_pol PF01743.20 GBG64220.1 - 2.1e-06 28.2 0.0 3.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain Enkurin PF13864.6 GBG64221.1 - 1.6e-17 63.7 2.5 4.2e-17 62.4 2.5 1.7 1 0 0 1 1 1 1 Calmodulin-binding SR-25 PF10500.9 GBG64221.1 - 0.00026 20.7 10.9 0.00048 19.8 10.9 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SKA1 PF07160.12 GBG64221.1 - 0.0022 17.9 1.9 0.0034 17.3 1.3 1.6 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Adeno_E1B_55K_N PF04623.12 GBG64222.1 - 6.9 7.4 18.0 5.7 7.7 5.1 2.1 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus Integrase_H2C2 PF17921.1 GBG64223.1 - 6.5e-15 55.0 2.3 1.1e-14 54.3 0.3 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG64223.1 - 5.8e-12 45.3 0.6 1.5e-11 44.0 0.1 2.1 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG64223.1 - 3.6e-09 36.8 0.0 8.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64223.1 - 0.0088 16.2 0.5 0.018 15.3 0.5 1.5 1 0 0 1 1 1 1 H2C2 zinc finger CDC45 PF02724.14 GBG64223.1 - 0.16 10.2 35.2 0.24 9.6 35.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GBG64223.1 - 2.9 6.3 11.2 4.5 5.7 11.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ion_trans PF00520.31 GBG64224.1 - 2e-15 56.7 14.0 2.3e-15 56.5 14.0 1.0 1 0 0 1 1 1 1 Ion transport protein PsbT PF01405.17 GBG64224.1 - 0.02 14.7 0.2 0.02 14.7 0.2 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre T protein DAGK_prokar PF01219.19 GBG64224.1 - 0.035 14.0 1.3 0.076 12.9 0.9 1.8 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Paf1 PF03985.13 GBG64226.1 - 0.59 9.1 7.4 0.71 8.8 7.4 1.1 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 GBG64226.1 - 2.1 6.4 4.2 2.3 6.2 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi PRA-CH PF01502.18 GBG64227.1 - 2.9e-26 91.1 0.1 5.3e-26 90.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 GBG64227.1 - 2.6e-11 43.8 0.0 5.3e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 GBG64227.1 - 2.2e-06 27.8 0.3 4.4e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain START PF01852.19 GBG64227.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 START domain YrbL-PhoP_reg PF10707.9 GBG64228.1 - 0.11 12.0 1.1 0.22 11.0 1.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FAM76 PF16046.5 GBG64228.1 - 0.12 11.7 9.5 0.16 11.3 9.5 1.2 1 0 0 1 1 1 0 FAM76 protein PspB PF06667.12 GBG64228.1 - 0.22 11.6 8.9 5.8 7.1 0.3 3.2 3 1 0 3 3 3 0 Phage shock protein B DUF3573 PF12097.8 GBG64228.1 - 0.26 10.1 1.2 0.33 9.7 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) APG6_N PF17675.1 GBG64228.1 - 0.51 10.9 26.8 0.2 12.2 1.4 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region MRP-S26 PF14943.6 GBG64228.1 - 0.55 10.1 14.2 21 4.9 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DUF4666 PF15697.5 GBG64228.1 - 0.84 10.3 6.0 0.66 10.7 3.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) UPF0242 PF06785.11 GBG64228.1 - 2.8 8.0 21.7 0.038 14.1 1.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Annexin PF00191.20 GBG64230.1 - 2.2e-43 146.1 0.9 1.9e-12 47.1 0.1 4.2 4 0 0 4 4 4 4 Annexin Asp_protease_2 PF13650.6 GBG64231.1 - 6.7e-08 33.1 0.0 2e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64231.1 - 3e-06 27.7 0.0 8.4e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64231.1 - 0.00011 21.9 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG64231.1 - 0.00045 20.1 0.1 0.0013 18.6 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG64231.1 - 0.0012 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG64231.1 - 0.0096 16.2 0.1 0.048 13.9 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG64231.1 - 1.2 8.4 12.7 2.6 7.3 8.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 GBG64231.1 - 6.7 7.2 9.1 1.1 9.8 0.1 2.9 2 0 0 2 2 2 0 Cell division protein ZapB RVT_1 PF00078.27 GBG64232.1 - 1.3e-22 80.5 0.0 2.5e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG64232.1 - 2.2e-07 31.4 0.0 5.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64232.1 - 1.6e-06 28.6 0.0 3.7e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64232.1 - 2.6e-05 24.0 0.0 6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64232.1 - 9.6e-05 22.2 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG64232.1 - 0.00015 22.0 6.9 0.0014 18.8 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein BLOC1_2 PF10046.9 GBG64232.1 - 0.57 10.5 9.0 0.095 13.0 3.3 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HIP1_clath_bdg PF16515.5 GBG64232.1 - 1.1 9.9 16.7 0.063 13.9 4.2 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FUSC PF04632.12 GBG64232.1 - 3.3 6.1 14.9 6.2 5.2 14.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Integrase_H2C2 PF17921.1 GBG64233.1 - 2.7e-13 49.8 0.1 6.5e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG64233.1 - 2.8e-09 37.2 0.0 1.6e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64233.1 - 5.3e-06 26.4 0.0 3.4e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64233.1 - 7.4e-06 26.1 0.0 1.8e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64233.1 - 0.0044 17.2 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG64233.1 - 0.031 14.5 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Lamprin PF06403.11 GBG64233.1 - 5.2 7.0 13.6 11 6.0 13.6 1.4 1 0 0 1 1 1 0 Lamprin RVT_1 PF00078.27 GBG64234.1 - 1.6e-29 103.0 0.0 2.3e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64234.1 - 1.3e-07 31.5 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64234.1 - 2.3e-07 31.3 0.0 3.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64234.1 - 1.7e-05 25.3 0.0 3.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64234.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Gp_dh_C PF02800.20 GBG64235.1 - 3.6e-66 221.6 0.6 1.4e-65 219.7 0.2 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG64235.1 - 3.3e-33 114.0 0.0 8.5e-33 112.7 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF5038 PF16441.5 GBG64235.1 - 0.13 12.3 0.1 0.42 10.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5038) zf-CCHC PF00098.23 GBG64236.1 - 0.00065 19.7 8.4 0.0038 17.2 1.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 GBG64236.1 - 0.0088 15.9 1.8 0.0088 15.9 1.8 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-C2H2_10 PF16588.5 GBG64236.1 - 6.6 6.6 6.1 0.8 9.5 0.9 2.0 2 0 0 2 2 2 0 C2H2 zinc-finger IF4E PF01652.18 GBG64239.1 - 4.1e-48 163.2 0.1 5.3e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cwf_Cwc_15 PF04889.12 GBG64242.1 - 2.7 7.6 32.7 3.8 7.2 32.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RVT_1 PF00078.27 GBG64243.1 - 4.6e-21 75.4 0.0 1.5e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64243.1 - 0.0029 17.4 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF588 PF04535.12 GBG64245.1 - 2.8e-21 75.9 6.2 3.7e-21 75.5 6.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF588) MARVEL PF01284.23 GBG64245.1 - 2.8e-06 27.4 10.3 4e-06 26.9 10.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Aminotran_4 PF01063.19 GBG64246.1 - 1.1e-32 113.7 0.0 1e-12 48.4 0.0 4.1 3 1 0 3 3 3 3 Amino-transferase class IV Myb_DNA-bind_4 PF13837.6 GBG64246.1 - 6e-05 23.4 1.8 0.00012 22.3 1.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF1707 PF08044.11 GBG64246.1 - 0.031 14.4 0.6 13 6.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) DUF3138 PF11336.8 GBG64247.1 - 0.48 9.0 4.7 7.1 5.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DASH_Hsk3 PF08227.11 GBG64247.1 - 1.3 9.4 6.6 0.29 11.5 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like PvlArgDC PF01862.16 GBG64248.1 - 1.8 8.4 0.0 1.8 8.4 0.0 3.1 2 1 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Dimer_Tnp_hAT PF05699.14 GBG64249.1 - 2.3e-05 24.1 0.1 4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DNA_pol_A_exo1 PF01612.20 GBG64251.1 - 9.1e-08 32.0 0.0 6.2e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease DNA_pol_A_exo1 PF01612.20 GBG64252.1 - 1.3e-07 31.5 0.0 7.5e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease Nop14 PF04147.12 GBG64253.1 - 0.15 10.3 58.1 0.18 10.0 58.1 1.0 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH PF17917.1 GBG64254.1 - 5.9e-23 81.2 0.0 1.4e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64254.1 - 1.6e-22 79.4 0.0 4e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64254.1 - 2.7e-18 65.8 0.7 6.9e-18 64.5 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64254.1 - 1.9e-16 60.3 0.0 5e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64254.1 - 0.09 13.0 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG64255.1 - 5.1e-31 107.5 0.0 8.7e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64255.1 - 7.6e-15 55.1 0.0 1.1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG64255.1 - 0.00028 20.6 0.1 0.053 13.2 0.0 2.4 2 1 0 2 2 2 2 Transposase DDE domain Peptidase_S9_N PF02897.15 GBG64256.1 - 1.1e-86 291.3 0.0 1.5e-86 290.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 GBG64256.1 - 3.1e-37 128.1 0.0 7.5e-35 120.3 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family RT_RNaseH_2 PF17919.1 GBG64256.1 - 3.6e-30 104.0 0.0 9.4e-30 102.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64256.1 - 1.1e-25 89.9 0.0 2.2e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64256.1 - 3.1e-19 68.8 0.1 7.9e-19 67.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64256.1 - 6.1e-15 55.5 0.0 1.4e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG64256.1 - 2.8e-12 46.6 0.2 5.2e-12 45.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrolase_4 PF12146.8 GBG64256.1 - 0.0071 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 GBG64256.1 - 0.017 14.7 0.1 0.034 13.7 0.1 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) zf-H2C2 PF09337.10 GBG64256.1 - 0.045 14.0 0.1 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG64256.1 - 0.19 11.7 3.9 0.49 10.4 3.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG64257.1 - 8.3e-08 32.5 1.8 1.4e-07 31.8 1.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG64257.1 - 0.00011 22.4 2.1 0.00066 19.8 2.1 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG64257.1 - 0.0064 16.8 0.6 0.013 15.8 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG64257.1 - 0.012 15.8 0.6 0.04 14.2 0.5 1.9 1 1 1 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG64257.1 - 0.055 13.5 2.8 0.1 12.7 2.8 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG64258.1 - 1.3e-29 102.9 0.0 1.8e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64258.1 - 1.7e-15 57.2 0.0 2.4e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG64260.1 - 3.3e-07 30.6 1.4 4.7e-06 26.9 0.7 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Glyco_hydro_14 PF01373.17 GBG64261.1 - 2.3e-107 359.4 0.0 4.5e-78 263.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 14 DUF659 PF04937.15 GBG64262.1 - 9.7e-18 64.5 0.0 1.7e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG64263.1 - 1.1e-25 90.0 0.0 1.8e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64263.1 - 2.9e-25 88.2 0.0 4.8e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64263.1 - 1.6e-11 44.2 0.0 2.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64263.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF2249 PF10006.9 GBG64263.1 - 0.056 13.3 0.0 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) PRIMA1 PF16101.5 GBG64266.1 - 0.053 13.6 3.0 1 9.4 0.5 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG64266.1 - 4.1 6.8 10.5 7.4 6.0 0.7 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal RT_RNaseH_2 PF17919.1 GBG64267.1 - 2.2e-30 104.6 0.0 8.5e-30 102.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64267.1 - 1.9e-28 98.8 0.0 4.2e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PNMA PF14893.6 GBG64267.1 - 0.025 14.0 0.1 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 PNMA Phage_lysozyme PF00959.19 GBG64267.1 - 0.045 14.2 0.2 0.7 10.4 0.0 2.8 3 0 0 3 3 3 0 Phage lysozyme RVT_1 PF00078.27 GBG64267.1 - 0.062 12.8 0.5 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Es2 PF09751.9 GBG64268.1 - 0.06 13.1 11.1 0.076 12.8 11.1 1.0 1 0 0 1 1 1 0 Nuclear protein Es2 FAM60A PF15396.6 GBG64268.1 - 0.13 12.2 5.9 0.16 11.9 5.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1690 PF07956.11 GBG64268.1 - 0.51 10.8 16.2 1.2 9.6 15.7 1.7 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) DUF4407 PF14362.6 GBG64268.1 - 3.3 7.0 9.5 3.8 6.8 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2052 PF09747.9 GBG64268.1 - 5.3 7.1 17.3 6.9 6.7 17.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RT_RNaseH_2 PF17919.1 GBG64269.1 - 4.2e-27 94.1 0.0 1.5e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64269.1 - 3e-24 85.3 0.0 1.2e-23 83.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64269.1 - 2.5e-23 82.8 0.0 3.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG64269.1 - 0.52 9.6 12.0 0.82 8.9 12.0 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG64269.1 - 8.3 5.7 12.0 12 5.2 12.0 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG64270.1 - 2.8 6.6 7.5 6 5.5 7.5 1.5 1 0 0 1 1 1 0 Presenilin NRDE-2 PF08424.10 GBG64270.1 - 8.5 5.4 11.8 1.8 7.6 1.2 2.2 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference Presenilin PF01080.17 GBG64274.1 - 0.044 12.5 22.1 0.051 12.3 22.1 1.1 1 0 0 1 1 1 0 Presenilin CLIP_1 PF18322.1 GBG64274.1 - 0.085 12.9 0.4 0.15 12.2 0.4 1.4 1 0 0 1 1 1 0 Serine protease Clip domain PPAF-2 SLC12 PF03522.15 GBG64274.1 - 0.1 11.6 13.0 0.12 11.4 13.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PhnH PF05845.12 GBG64274.1 - 0.92 9.2 6.1 1.3 8.7 6.1 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) BUD22 PF09073.10 GBG64274.1 - 3.1 7.0 48.8 4.4 6.6 48.8 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GBG64274.1 - 5.3 5.7 21.9 8.4 5.0 21.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.6 GBG64274.1 - 9.9 4.8 24.0 14 4.3 24.0 1.2 1 0 0 1 1 1 0 Raftlin HA2 PF04408.23 GBG64275.1 - 0.19 12.0 7.5 2.1 8.7 7.5 2.1 1 1 0 1 1 1 0 Helicase associated domain (HA2) TRAP_alpha PF03896.16 GBG64275.1 - 1.7 7.8 6.0 2.4 7.3 6.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GTP_EFTU PF00009.27 GBG64276.1 - 1e-55 188.3 0.0 1.6e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ubie_methyltran PF01209.18 GBG64276.1 - 2.5e-55 187.3 0.0 4.9e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family LepA_C PF06421.12 GBG64276.1 - 3.9e-50 168.5 0.9 8.8e-50 167.4 0.9 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 GBG64276.1 - 2.2e-20 72.5 0.1 5.2e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Methyltransf_25 PF13649.6 GBG64276.1 - 4.4e-20 72.2 0.0 2.3e-19 69.9 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG64276.1 - 6.8e-20 71.5 0.1 3.4e-19 69.3 0.1 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG64276.1 - 2.6e-17 63.0 0.0 5.9e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG64276.1 - 9.3e-10 39.1 0.0 2.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GTP_EFTU_D2 PF03144.25 GBG64276.1 - 3.3e-09 37.0 0.2 7.9e-09 35.8 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Methyltransf_23 PF13489.6 GBG64276.1 - 4.2e-06 26.7 0.0 8.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GBG64276.1 - 2.4e-05 24.2 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) EFG_II PF14492.6 GBG64276.1 - 3.9e-05 23.7 0.0 0.0011 19.0 0.0 2.6 2 1 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GBG64276.1 - 4.9e-05 23.4 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 GBG64276.1 - 0.00015 21.4 0.0 0.00037 20.1 0.0 1.7 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 GBG64276.1 - 0.0024 17.7 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Methyltransf_32 PF13679.6 GBG64276.1 - 0.0028 17.7 0.0 0.0084 16.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 GBG64276.1 - 0.0056 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GBG64276.1 - 0.036 13.5 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase MMR_HSR1_Xtn PF16897.5 GBG64276.1 - 0.074 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GCD14 PF08704.10 GBG64276.1 - 0.12 12.0 0.0 0.81 9.3 0.0 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Raffinose_syn PF05691.12 GBG64277.1 - 1e-292 972.6 0.0 2.3e-256 852.3 0.0 3.0 3 0 0 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Raffinose_syn PF05691.12 GBG64278.1 - 4.1e-257 854.8 0.0 4.1e-207 689.5 0.0 3.0 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 MTHFR PF02219.17 GBG64279.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Trypan_PARP PF05887.11 GBG64279.1 - 0.074 13.0 9.1 0.21 11.6 9.1 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mem_trans PF03547.18 GBG64280.1 - 1.5e-72 244.2 0.0 5.3e-72 242.3 0.0 1.8 1 1 0 1 1 1 1 Membrane transport protein zf-CCHC PF00098.23 GBG64281.1 - 6.5e-06 26.0 4.0 6.5e-06 26.0 4.0 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG64281.1 - 0.015 15.1 3.8 0.015 15.1 3.8 1.9 2 0 0 2 2 2 0 Zinc knuckle HAUS6_N PF14661.6 GBG64281.1 - 0.017 14.7 1.1 0.031 13.9 1.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Ank_4 PF13637.6 GBG64282.1 - 9.5e-23 80.3 4.0 4.2e-09 36.8 0.2 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GBG64282.1 - 1.6e-18 67.1 0.2 1.5e-11 44.7 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GBG64282.1 - 2.4e-18 66.0 1.2 1.7e-08 34.5 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GBG64282.1 - 1.6e-14 53.6 2.3 7e-06 26.3 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 GBG64282.1 - 1e-10 40.8 0.3 0.0031 17.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat CobT PF06213.12 GBG64282.1 - 0.0034 16.8 32.0 0.0034 16.8 32.0 3.0 3 0 0 3 3 3 1 Cobalamin biosynthesis protein CobT RT_RNaseH_2 PF17919.1 GBG64283.1 - 1.2e-29 102.3 0.0 1.2e-14 54.1 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64283.1 - 4.9e-29 100.7 0.0 1.2e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64283.1 - 2.4e-24 86.1 0.1 3.7e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_16 PF13191.6 GBG64284.1 - 0.0026 18.2 0.1 0.015 15.7 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 GBG64284.1 - 0.0028 17.3 0.0 0.049 13.2 0.0 2.1 1 1 0 2 2 2 1 AAA domain NACHT PF05729.12 GBG64284.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 NACHT domain Roc PF08477.13 GBG64284.1 - 0.027 14.7 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DAP3 PF10236.9 GBG64284.1 - 0.045 12.9 0.0 4.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 GBG64284.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC TniB PF05621.11 GBG64284.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 Bacterial TniB protein ResIII PF04851.15 GBG64284.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ribosomal_S9 PF00380.19 GBG64284.1 - 0.15 12.5 0.0 0.22 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Cnl2_NKP2 PF09447.10 GBG64284.1 - 0.18 12.0 0.1 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Cnl2/NKP2 family protein AAA_14 PF13173.6 GBG64284.1 - 0.19 11.8 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GBG64285.1 - 0.0031 17.9 0.1 0.013 15.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 GBG64285.1 - 0.0038 16.8 0.0 0.053 13.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 GBG64285.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.6 1 1 0 1 1 1 0 NACHT domain Roc PF08477.13 GBG64285.1 - 0.027 14.7 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DAP3 PF10236.9 GBG64285.1 - 0.05 12.8 0.0 5.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 GBG64285.1 - 0.091 12.2 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Bacterial TniB protein ATPase PF06745.13 GBG64285.1 - 0.097 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 GBG64285.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Cnl2_NKP2 PF09447.10 GBG64285.1 - 0.16 12.1 0.2 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Cnl2/NKP2 family protein AAA_14 PF13173.6 GBG64285.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain KH_7 PF17214.3 GBG64286.1 - 0.015 15.3 1.1 0.59 10.1 0.0 2.4 2 0 0 2 2 2 0 KH domain RVT_1 PF00078.27 GBG64287.1 - 0.0015 18.1 0.0 1.7 8.1 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) GP38 PF05268.11 GBG64288.1 - 2.7 7.6 28.3 3.5 7.2 28.3 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 PrmA PF06325.13 GBG64291.1 - 0.0039 16.6 0.0 0.025 14.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Collagen PF01391.18 GBG64293.1 - 0.002 17.8 3.7 0.002 17.8 3.7 1.4 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) DNA_pol_phi PF04931.13 GBG64293.1 - 0.47 8.5 11.8 0.55 8.3 11.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Bd3614-deam PF14439.6 GBG64293.1 - 1.8 8.6 7.1 3.1 7.9 7.1 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase Cnd2 PF05786.14 GBG64293.1 - 4.2 5.9 7.9 4.6 5.8 7.9 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Myb_DNA-bind_4 PF13837.6 GBG64294.1 - 5.1e-10 39.6 3.0 6.8e-10 39.2 0.2 2.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG64294.1 - 0.024 15.0 1.6 0.028 14.7 0.1 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like IMS PF00817.20 GBG64296.1 - 7.2e-47 159.1 0.0 1.3e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 GBG64296.1 - 5.6e-15 56.1 0.3 1.1e-14 55.1 0.3 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 GBG64296.1 - 3.7e-06 26.4 1.5 6.8e-06 25.6 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 GBG64296.1 - 0.011 16.0 0.0 0.035 14.5 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif zf-RanBP PF00641.18 GBG64296.1 - 0.014 14.7 9.3 0.017 14.4 3.4 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF3449 PF11931.8 GBG64296.1 - 0.033 14.0 1.1 0.23 11.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) RVT_1 PF00078.27 GBG64297.1 - 6.8e-31 107.5 0.1 9.5e-31 107.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG64299.1 - 7.8e-12 45.1 0.1 6.1e-11 42.2 0.0 2.5 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64299.1 - 0.00088 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DUF659 PF04937.15 GBG64299.1 - 0.00096 19.0 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG64301.1 - 4.9e-07 30.1 4.6 6.6e-07 29.6 0.6 2.4 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG64301.1 - 0.023 15.0 0.6 0.07 13.5 0.6 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-CCHC PF00098.23 GBG64302.1 - 5.3e-05 23.1 1.8 0.00011 22.1 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG64302.1 - 0.061 13.3 0.3 0.2 11.7 0.3 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG64302.1 - 0.062 13.0 0.6 0.12 12.1 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DASH_Hsk3 PF08227.11 GBG64302.1 - 0.12 12.7 0.2 0.27 11.6 0.2 1.5 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like zf-CCHC_2 PF13696.6 GBG64302.1 - 0.31 10.9 2.3 0.67 9.8 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2347 PF09804.9 GBG64302.1 - 1.8 8.1 5.6 3.1 7.3 5.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4407 PF14362.6 GBG64302.1 - 5.1 6.4 10.0 6.6 6.0 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Asp_protease_2 PF13650.6 GBG64303.1 - 0.078 13.6 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease SPX PF03105.19 GBG64305.1 - 0.015 15.2 9.6 0.018 15.0 9.6 1.3 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 GBG64305.1 - 3 6.6 15.1 3.4 6.4 14.7 1.3 1 1 0 1 1 1 0 Golgi-body localisation protein domain Myb_DNA-bind_4 PF13837.6 GBG64306.1 - 1.8e-09 37.8 3.3 1.8e-09 37.8 3.3 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG64306.1 - 7.3e-05 23.0 1.2 0.0013 19.0 1.3 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG64306.1 - 0.00041 20.5 1.1 0.00065 19.9 1.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG64306.1 - 0.0014 18.7 0.9 0.0028 17.7 0.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG64306.1 - 0.0043 17.2 0.9 0.014 15.6 0.9 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Glyco_transf_10 PF00852.19 GBG64307.1 - 1.4e-28 99.8 0.0 3.6e-28 98.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Ribosomal_L22e PF01776.17 GBG64308.1 - 1.8e-45 153.8 4.0 2.3e-45 153.5 4.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Vps35 PF03635.17 GBG64309.1 - 4.4e-228 759.4 1.7 9.4e-176 586.4 0.3 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 RT_RNaseH_2 PF17919.1 GBG64310.1 - 1.6e-35 121.1 0.1 2.9e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64310.1 - 6.7e-30 103.5 0.0 1.2e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64310.1 - 5.7e-16 58.4 0.1 1.2e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG64310.1 - 3e-05 23.6 0.1 5.7e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG64311.1 - 1.8 8.8 6.2 0.18 11.9 0.7 2.3 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG64313.1 - 2.6e-28 99.0 0.5 5.1e-28 98.1 0.2 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64313.1 - 0.0088 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Seryl_tRNA_N PF02403.22 GBG64313.1 - 0.025 14.8 0.1 0.09 13.0 0.1 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Retrotrans_gag PF03732.17 GBG64313.1 - 0.056 13.7 0.6 0.3 11.4 0.6 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein ZapB PF06005.12 GBG64313.1 - 0.45 11.0 0.0 0.45 11.0 0.0 3.0 4 0 0 4 4 4 0 Cell division protein ZapB NPV_P10 PF05531.12 GBG64313.1 - 0.83 10.2 2.5 16 6.0 2.5 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 GBG64314.1 - 8e-47 159.2 21.1 8e-47 159.2 21.1 3.2 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding ELM2 PF01448.24 GBG64314.1 - 0.1 13.4 0.1 0.7 10.7 0.1 2.5 1 0 0 1 1 1 0 ELM2 domain PHA_gran_rgn PF09650.10 GBG64314.1 - 2.4 8.5 11.6 0.38 11.1 1.0 3.7 3 1 0 3 3 3 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) RT_RNaseH_2 PF17919.1 GBG64315.1 - 1.4e-34 118.1 0.1 3.2e-34 117.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64315.1 - 3.3e-31 107.7 0.2 7.6e-31 106.5 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG64315.1 - 0.015 15.2 0.0 0.088 12.7 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG64315.1 - 0.059 13.7 0.4 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein GAS PF13851.6 GBG64316.1 - 6.4e-30 104.0 4.9 1.5e-29 102.8 4.9 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding RVT_1 PF00078.27 GBG64316.1 - 9.8e-28 97.2 0.0 1.7e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64316.1 - 1.6e-22 79.8 0.0 3.6e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64316.1 - 1.6e-20 73.0 0.0 3.9e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64316.1 - 8.6e-17 61.0 0.1 2.7e-16 59.4 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG64316.1 - 0.0034 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG64316.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Metal_resist PF13801.6 GBG64316.1 - 0.021 15.0 0.2 0.021 15.0 0.2 2.7 2 0 0 2 2 2 0 Heavy-metal resistance rve PF00665.26 GBG64316.1 - 0.034 14.3 0.0 0.51 10.5 0.0 2.5 1 1 1 2 2 2 0 Integrase core domain NYD-SP28 PF14772.6 GBG64316.1 - 0.2 11.7 4.3 0.14 12.2 1.5 2.1 1 1 0 1 1 1 0 Sperm tail DUF2076 PF09849.9 GBG64318.1 - 0.029 14.4 11.4 0.038 14.0 11.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SDA1 PF05285.12 GBG64318.1 - 0.67 9.3 72.0 0.73 9.2 72.0 1.0 1 0 0 1 1 1 0 SDA1 DUF4045 PF13254.6 GBG64318.1 - 2.6 7.6 23.7 2.6 7.6 23.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RT_RNaseH_2 PF17919.1 GBG64319.1 - 4.4e-53 177.5 0.0 1.1e-29 102.4 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64319.1 - 6.2e-42 142.2 0.0 1e-30 106.1 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Tyr_Deacylase PF02580.16 GBG64319.1 - 4.4e-38 131.0 0.0 1e-22 81.2 0.0 2.7 2 0 0 2 2 2 2 D-Tyr-tRNA(Tyr) deacylase RVT_1 PF00078.27 GBG64319.1 - 1.4e-27 96.6 0.1 2.5e-27 95.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG64319.1 - 0.0084 14.5 17.5 0.0044 15.4 8.6 2.2 2 0 0 2 2 2 2 CDC45-like protein PikAIV_N PF18605.1 GBG64319.1 - 0.09 12.4 5.6 0.48 10.1 2.8 2.8 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DRY_EERY PF09750.9 GBG64319.1 - 0.2 11.9 0.0 0.2 11.9 0.0 3.6 3 0 0 3 3 3 0 Alternative splicing regulator Na_Ca_ex PF01699.24 GBG64320.1 - 4.3e-13 49.5 34.2 2.5e-09 37.3 16.3 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein EF-hand_1 PF00036.32 GBG64320.1 - 7.1e-08 31.5 2.9 0.0014 18.0 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 GBG64320.1 - 1.4e-07 31.9 2.5 3.5e-07 30.6 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG64320.1 - 1.2e-06 27.9 0.1 0.01 15.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GBG64320.1 - 3.9e-05 22.9 4.4 0.021 14.3 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GBG64320.1 - 0.023 14.5 4.2 0.33 10.8 0.0 3.1 4 0 0 4 4 4 0 EF-hand domain pair DUF928 PF06051.12 GBG64321.1 - 0.49 10.2 4.1 3.2 7.6 0.5 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) RT_RNaseH_2 PF17919.1 GBG64322.1 - 1.5e-31 108.4 0.0 2.9e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64322.1 - 1.1e-26 93.1 0.0 2.2e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64322.1 - 1e-15 57.6 0.1 2.1e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64322.1 - 2.5e-13 50.2 0.1 9e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG64322.1 - 4.9e-10 39.3 0.1 1e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG64322.1 - 0.016 15.5 0.0 0.049 13.9 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Glyco_hydro_15 PF00723.21 GBG64322.1 - 0.042 12.6 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 RT_RNaseH_2 PF17919.1 GBG64324.1 - 1.4e-19 69.9 0.0 4.5e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64324.1 - 2.9e-19 69.5 0.2 1.1e-18 67.6 0.0 1.8 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64324.1 - 5.4e-11 42.7 0.0 1.3e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64324.1 - 0.02 15.0 2.3 0.048 13.8 2.3 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain RVP_2 PF08284.11 GBG64324.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 GBG64324.1 - 0.057 13.6 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain TolA_bind_tri PF16331.5 GBG64324.1 - 0.35 11.0 2.2 0.82 9.8 2.2 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation SlyX PF04102.12 GBG64324.1 - 2.5 8.8 4.8 6.8 7.4 0.2 2.9 3 0 0 3 3 3 0 SlyX RT_RNaseH PF17917.1 GBG64325.1 - 9.8e-30 103.0 0.0 2.1e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64325.1 - 1.1e-29 102.4 0.0 6.5e-29 99.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG64325.1 - 0.00062 19.5 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase DUF4318 PF14201.6 GBG64326.1 - 0.074 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) MPM1 PF17234.2 GBG64327.1 - 2.4 8.4 10.5 2.4 8.4 9.5 1.5 1 1 1 2 2 2 0 Mitochondrial peculiar membrane protein 1 ICA69 PF04629.14 GBG64327.1 - 4.6 7.5 6.6 5.6 7.2 6.6 1.1 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain Sel1 PF08238.12 GBG64328.1 - 5.2e-26 90.5 23.2 2.3e-06 28.1 0.1 6.5 6 0 0 6 6 6 6 Sel1 repeat F-box-like PF12937.7 GBG64328.1 - 1.6e-08 34.3 0.0 3.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG64328.1 - 7.4e-06 25.7 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 F-box domain TPR_12 PF13424.6 GBG64328.1 - 0.036 14.3 3.2 0.073 13.4 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG64328.1 - 0.083 12.8 3.6 0.18 11.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG64328.1 - 1.9 9.2 8.9 0.52 11.0 1.5 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG64329.1 - 2.9e-34 118.5 0.0 5e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64329.1 - 2.4e-30 104.5 0.0 8.4e-30 102.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64329.1 - 8.8e-29 99.9 0.2 2.7e-28 98.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG64330.1 - 2.8e-11 43.1 0.0 6.4e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Secretin_N_2 PF07655.13 GBG64330.1 - 0.019 15.5 7.8 0.019 15.5 7.8 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain RNase_T PF00929.24 GBG64331.1 - 1.4e-27 97.3 0.0 1.9e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Hum_adeno_E3A PF05393.11 GBG64331.1 - 0.27 11.2 3.0 0.19 11.7 0.8 1.8 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein RT_RNaseH PF17917.1 GBG64332.1 - 6.6e-27 93.8 0.1 1.5e-26 92.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64332.1 - 1.5e-17 63.5 0.0 4.1e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Snapin_Pallidin PF14712.6 GBG64332.1 - 7.4e-17 61.6 0.4 2.9e-15 56.4 0.0 3.0 2 0 0 2 2 2 1 Snapin/Pallidin Retrotrans_gag PF03732.17 GBG64332.1 - 0.042 14.1 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein Phage_GPO PF05929.11 GBG64332.1 - 0.088 12.4 0.0 0.088 12.4 0.0 2.7 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Ribosomal_S18 PF01084.20 GBG64333.1 - 1.9e-14 53.6 0.3 3.6e-14 52.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 gag-asp_proteas PF13975.6 GBG64334.1 - 1.6e-08 35.0 0.0 3.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64334.1 - 3.4e-07 30.8 0.0 9.2e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64334.1 - 2.2e-05 24.2 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG64334.1 - 0.0036 17.3 1.0 0.0086 16.1 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 GBG64334.1 - 0.056 13.8 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Rit1_C PF17184.4 GBG64335.1 - 1.1e-82 277.5 0.0 6.3e-52 176.7 0.3 2.2 2 0 0 2 2 2 2 Rit1 N-terminal domain BUD22 PF09073.10 GBG64335.1 - 5.9e-08 32.5 18.3 0.01 15.2 20.2 2.7 2 1 0 2 2 2 2 BUD22 SpoU_methylase PF00588.19 GBG64336.1 - 5.5e-31 107.6 0.0 7.9e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Init_tRNA_PT PF04179.12 GBG64337.1 - 3.7e-23 81.9 0.0 4.9e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Rit1 DUSP-like domain ATP-synt_DE_N PF02823.16 GBG64338.1 - 1.8e-17 63.0 0.0 2.5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF4187 PF13821.6 GBG64339.1 - 0.022 14.5 1.7 0.022 14.5 1.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG64339.1 - 0.024 14.9 4.8 0.034 14.4 0.2 3.1 3 1 1 4 4 4 0 Retrotransposon gag protein DUF16 PF01519.16 GBG64339.1 - 0.081 13.4 2.0 0.28 11.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4340 PF14238.6 GBG64339.1 - 0.083 12.9 0.0 0.23 11.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4340) BLOC1_2 PF10046.9 GBG64339.1 - 2.5 8.5 5.6 1.7 9.0 2.8 2.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 GBG64339.1 - 3.4 7.9 9.8 0.15 12.3 1.5 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RVT_1 PF00078.27 GBG64342.1 - 4.3e-35 121.2 0.1 1.4e-34 119.5 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spermine_synth PF01564.17 GBG64342.1 - 1.6e-27 96.2 0.0 9.6e-14 51.2 0.0 2.4 2 0 0 2 2 2 2 Spermine/spermidine synthase domain RT_RNaseH_2 PF17919.1 GBG64342.1 - 2.1e-14 53.3 0.0 9.7e-14 51.2 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Spermine_synt_N PF17284.2 GBG64342.1 - 3.3e-13 49.3 0.1 5.6e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain RT_RNaseH PF17917.1 GBG64342.1 - 0.00053 20.2 0.0 0.0017 18.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Methyltransf_25 PF13649.6 GBG64342.1 - 0.0023 18.6 0.1 11 6.8 0.0 4.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 GBG64342.1 - 0.0056 17.4 0.2 0.25 12.1 0.0 3.6 3 1 1 4 4 4 1 Methyltransferase domain Retrotrans_gag PF03732.17 GBG64342.1 - 0.0078 16.5 13.7 0.011 16.0 0.1 5.3 6 0 0 6 6 6 1 Retrotransposon gag protein Methyltransf_30 PF05430.11 GBG64342.1 - 0.1 12.5 0.0 0.41 10.5 0.0 2.0 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF3990 PF13151.6 GBG64342.1 - 0.17 11.6 0.6 6.9 6.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) VIR_N PF15912.5 GBG64343.1 - 6.5 6.3 11.2 12 5.4 11.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal DUF659 PF04937.15 GBG64344.1 - 9.8e-20 71.0 0.0 1.9e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG64344.1 - 0.019 15.0 3.6 0.024 14.6 1.6 2.2 2 0 0 2 2 2 0 BED zinc finger PyrI_C PF02748.15 GBG64344.1 - 0.066 13.1 1.5 0.11 12.5 0.4 1.9 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 GBG64344.1 - 0.077 13.9 0.6 0.42 11.6 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 GBG64344.1 - 0.35 11.4 3.9 0.87 10.1 1.9 2.5 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger RT_RNaseH_2 PF17919.1 GBG64345.1 - 7.6e-31 106.1 0.0 2e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64345.1 - 3.1e-30 104.6 0.0 7.4e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64345.1 - 3.7e-19 68.6 0.5 7.7e-19 67.6 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG64345.1 - 1.7e-11 44.1 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG64345.1 - 0.00047 20.3 0.5 0.0011 19.1 0.1 1.9 2 0 0 2 2 2 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG64345.1 - 0.38 10.3 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG64346.1 - 6.8e-67 221.8 0.0 1.1e-25 89.6 0.0 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64346.1 - 4.4e-60 200.5 0.0 1.1e-25 89.9 0.1 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64346.1 - 2.7e-51 174.2 0.1 1.6e-26 93.2 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64346.1 - 3.1e-19 68.8 0.4 8.7e-19 67.4 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG64346.1 - 3.2e-08 33.8 0.1 2.3e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG64346.1 - 2.9e-05 23.9 0.0 6.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64346.1 - 0.00017 22.1 0.0 0.00053 20.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64346.1 - 0.00034 21.2 0.0 0.00099 19.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG64346.1 - 0.0012 19.1 4.2 0.012 15.9 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG64346.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG64347.1 - 3.8e-22 78.9 0.0 7.5e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64347.1 - 1.9e-18 66.3 0.0 7.3e-18 64.5 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64347.1 - 5e-09 36.4 0.0 1.6e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG64347.1 - 2.4e-07 30.9 5.6 0.0062 16.8 0.0 4.3 4 0 0 4 4 4 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG64347.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Flot PF15975.5 GBG64347.1 - 7.8 6.7 10.7 17 5.6 10.7 1.5 1 0 0 1 1 1 0 Flotillin Integrase_H2C2 PF17921.1 GBG64348.1 - 1.4e-17 63.5 0.2 4.4e-17 61.9 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64348.1 - 5.2e-09 36.3 0.0 1.8e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG64348.1 - 0.0073 16.6 0.0 0.0073 16.6 0.0 5.4 7 0 0 7 7 7 1 Retrotransposon gag protein DUF1664 PF07889.12 GBG64348.1 - 0.6 10.2 13.5 0.16 12.0 2.9 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GBG64348.1 - 6.4 6.8 6.7 21 5.1 0.9 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RVT_1 PF00078.27 GBG64349.1 - 1.3e-23 83.7 0.1 1.9e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64349.1 - 2.2e-23 82.2 0.0 6.3e-23 80.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64349.1 - 3.4e-19 69.1 0.1 8.1e-19 67.9 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG64350.1 - 2.5e-34 118.4 0.1 6.1e-34 117.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG64350.1 - 0.019 14.7 21.4 0.25 11.3 4.8 4.0 3 0 0 3 3 3 0 AT hook motif RT_RNaseH_2 PF17919.1 GBG64351.1 - 1.5e-22 79.5 0.0 2.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64351.1 - 1.8e-22 79.6 0.0 3e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64351.1 - 5.2e-19 68.1 1.2 1.2e-18 67.0 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG64351.1 - 3.5e-09 36.5 0.4 6.9e-09 35.5 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG64351.1 - 0.013 15.7 0.0 0.036 14.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 GBG64352.1 - 6.1e-06 26.0 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64352.1 - 8.3e-05 23.1 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64352.1 - 0.00014 22.4 0.0 0.00032 21.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Snf7 PF03357.21 GBG64353.1 - 0.00051 19.7 4.1 0.001 18.7 4.1 1.4 1 0 0 1 1 1 1 Snf7 V_ATPase_I PF01496.19 GBG64353.1 - 0.0034 15.4 5.0 0.0035 15.4 5.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SYF2 PF08231.12 GBG64353.1 - 0.0044 17.4 4.1 0.0044 17.4 4.1 1.6 2 0 0 2 2 2 1 SYF2 splicing factor Med9 PF07544.13 GBG64353.1 - 0.014 15.5 5.3 5.2 7.2 0.0 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Plasmid_RAQPRD PF09686.10 GBG64353.1 - 0.033 14.4 2.7 0.035 14.3 1.5 1.7 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) IML1 PF12257.8 GBG64353.1 - 0.037 13.2 2.8 0.052 12.7 2.8 1.2 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 CdiI_2 PF18593.1 GBG64353.1 - 0.053 14.2 0.9 0.12 13.0 0.9 1.6 1 0 0 1 1 1 0 CdiI immunity protein PDH PF02153.17 GBG64353.1 - 0.057 12.4 1.9 0.08 11.9 0.6 1.8 2 0 0 2 2 2 0 Prephenate dehydrogenase DASH_Duo1 PF08651.10 GBG64353.1 - 0.058 13.2 0.8 2.5 7.9 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 Exonuc_VII_L PF02601.15 GBG64353.1 - 0.16 11.5 5.4 0.18 11.4 5.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Med8 PF10232.9 GBG64353.1 - 0.3 10.6 10.4 0.29 10.7 8.7 1.7 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Poty_PP PF08440.10 GBG64353.1 - 0.41 9.7 4.4 0.56 9.2 4.4 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein TMPIT PF07851.13 GBG64353.1 - 0.52 9.5 7.0 0.75 9.0 7.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 GBG64353.1 - 0.83 9.7 5.1 1.6 8.8 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GBG64353.1 - 1.5 9.0 7.9 1.2 9.3 5.8 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 GBG64353.1 - 5.1 7.1 13.1 8.6 6.4 13.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RT_RNaseH_2 PF17919.1 GBG64355.1 - 3.8e-31 107.1 0.1 7.5e-31 106.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64355.1 - 3e-26 91.7 0.1 6.5e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64355.1 - 5.8e-19 68.0 0.1 1.3e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain SIR2 PF02146.17 GBG64355.1 - 1.9e-18 67.0 0.1 1.1e-09 38.5 0.0 3.0 2 1 1 3 3 3 2 Sir2 family rve PF00665.26 GBG64355.1 - 2.7e-13 50.2 0.0 6.7e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG64355.1 - 0.00052 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG64355.1 - 0.0026 18.0 0.0 0.0067 16.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger HAUS6_N PF14661.6 GBG64355.1 - 0.1 12.1 1.1 0.23 11.0 1.1 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RT_RNaseH_2 PF17919.1 GBG64356.1 - 2.1e-31 107.9 0.1 4.6e-31 106.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64356.1 - 1.3e-26 92.9 0.1 4e-26 91.4 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64356.1 - 3.7e-19 68.6 0.1 8.5e-19 67.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64356.1 - 1.6e-13 50.9 0.0 4e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG64356.1 - 0.00017 21.2 0.1 0.00037 20.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG64356.1 - 0.0014 18.8 0.0 0.0045 17.2 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG64357.1 - 4.9e-28 98.2 0.6 1.6e-27 96.5 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64357.1 - 4.1e-25 87.7 0.0 1.2e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64357.1 - 8.9e-25 87.0 0.0 2e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG64357.1 - 0.00076 19.7 0.2 0.014 15.7 0.0 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG64357.1 - 0.015 15.1 0.8 0.015 15.1 0.8 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) LRRFIP PF09738.9 GBG64357.1 - 0.22 10.9 0.0 0.47 9.9 0.0 1.4 1 0 0 1 1 1 0 LRRFIP family TPP_enzyme_M PF00205.22 GBG64358.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain RT_RNaseH_2 PF17919.1 GBG64359.1 - 0.0002 21.3 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64359.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Nop14 PF04147.12 GBG64359.1 - 0.041 12.1 28.8 0.062 11.5 28.8 1.2 1 0 0 1 1 1 0 Nop14-like family Plasmodium_Vir PF05795.11 GBG64359.1 - 0.4 10.0 6.7 0.47 9.8 6.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 GBG64359.1 - 2.8 6.6 15.1 3.6 6.2 15.1 1.3 1 0 0 1 1 1 0 Presenilin FancD2 PF14631.6 GBG64359.1 - 3.7 4.8 5.5 5 4.4 5.5 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Serinc PF03348.15 GBG64359.1 - 4.6 6.1 3.8 5.9 5.7 3.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.7 GBG64359.1 - 7.1 4.6 14.3 8.8 4.3 14.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RT_RNaseH_2 PF17919.1 GBG64360.1 - 6.2e-26 90.4 0.0 1.2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64360.1 - 6.3e-14 52.1 0.0 1.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64360.1 - 2.4e-12 46.8 0.1 3.6e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64361.1 - 6.5e-32 109.5 0.0 1.6e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64361.1 - 2.8e-30 104.7 0.0 9.2e-30 103.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64361.1 - 5.4e-29 101.3 0.0 1e-28 100.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64361.1 - 8.8e-18 64.2 0.3 2.1e-17 62.9 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG64361.1 - 2.2e-08 34.0 0.0 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64361.1 - 0.00015 22.3 0.0 0.00031 21.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64361.1 - 0.03 14.9 0.0 0.066 13.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4140 PF13600.6 GBG64361.1 - 0.13 12.8 7.8 7.1 7.1 0.2 3.9 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Snapin_Pallidin PF14712.6 GBG64361.1 - 0.27 11.7 7.1 1.5 9.3 0.1 3.0 2 0 0 2 2 2 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 GBG64361.1 - 5 6.6 7.6 9.2 5.7 7.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlxA PF14282.6 GBG64361.1 - 8.9 6.4 10.8 19 5.3 0.1 3.0 3 0 0 3 3 3 0 FlxA-like protein RT_RNaseH_2 PF17919.1 GBG64362.1 - 2.3e-34 117.4 0.0 5.3e-34 116.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64362.1 - 5.6e-31 106.9 0.0 1.3e-30 105.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64362.1 - 2.1e-30 105.9 0.2 3.8e-30 105.1 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64362.1 - 1e-11 44.8 0.0 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG64363.1 - 0.019 15.2 0.0 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2730 PF10805.8 GBG64363.1 - 0.053 13.6 0.8 0.81 9.8 0.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) SKA1 PF07160.12 GBG64363.1 - 0.065 13.1 2.1 0.19 11.5 1.4 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 FUSC PF04632.12 GBG64363.1 - 0.17 10.4 2.4 0.19 10.3 2.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.12 GBG64363.1 - 0.46 11.1 11.0 0.22 12.2 1.1 2.5 1 1 1 2 2 2 0 SlyX DUF1664 PF07889.12 GBG64363.1 - 0.47 10.5 2.3 4.4 7.3 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 GBG64363.1 - 0.75 10.3 3.7 2 9.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 RVT_1 PF00078.27 GBG64364.1 - 4.7e-24 85.1 0.1 8.3e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG64364.1 - 1.1e-12 48.3 0.2 5.3e-05 23.7 0.0 3.3 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64364.1 - 2.9e-12 47.0 0.0 3.1e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG64364.1 - 5.8e-09 35.8 0.0 2e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64364.1 - 1.1e-07 31.7 0.0 0.0035 17.1 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease rve PF00665.26 GBG64364.1 - 0.0025 18.0 0.0 0.0086 16.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.20 GBG64364.1 - 0.0087 16.4 0.0 6 7.2 0.0 2.8 2 0 0 2 2 2 2 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG64365.1 - 4.5e-30 103.6 0.0 9.8e-30 102.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64365.1 - 8e-27 93.6 0.0 1.5e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64365.1 - 1.9e-11 43.9 0.1 2.7e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG64365.1 - 0.015 15.1 0.0 0.46 10.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Nop14 PF04147.12 GBG64365.1 - 0.65 8.1 23.2 0.89 7.7 23.2 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 GBG64365.1 - 1 9.6 14.8 1.9 8.7 14.8 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2201_N PF13203.6 GBG64365.1 - 3.3 7.2 7.3 4.6 6.8 6.6 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain Nop14 PF04147.12 GBG64366.1 - 0.23 9.6 23.0 0.28 9.3 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG64366.1 - 0.37 10.2 26.1 0.47 9.8 26.1 1.1 1 0 0 1 1 1 0 SDA1 DUF3807 PF12720.7 GBG64366.1 - 0.4 10.9 13.2 0.62 10.3 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CDC45 PF02724.14 GBG64366.1 - 0.49 8.6 16.1 0.77 8.0 16.1 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG64366.1 - 1.8 7.9 27.8 2.3 7.4 27.8 1.1 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 GBG64366.1 - 4.4 6.6 15.6 7 6.0 15.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SAPS PF04499.15 GBG64366.1 - 5 5.8 7.1 5.5 5.7 7.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dymeclin PF09742.9 GBG64367.1 - 5.3e-138 461.2 0.0 6.2e-138 461.0 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 GBG64367.1 - 9.4e-14 50.5 11.9 5.5e-08 31.4 8.6 3.1 3 0 0 3 3 3 3 High-temperature-induced dauer-formation protein CsiD PF08943.10 GBG64368.1 - 0.016 14.4 0.7 0.027 13.6 0.1 1.7 2 0 0 2 2 2 0 CsiD Retrotrans_gag PF03732.17 GBG64368.1 - 0.016 15.5 2.8 0.016 15.5 2.8 3.9 3 2 2 5 5 5 0 Retrotransposon gag protein TSC22 PF01166.18 GBG64368.1 - 0.69 10.3 4.5 0.79 10.1 2.4 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family CRT10 PF08728.10 GBG64368.1 - 1.4 7.0 5.2 2.3 6.3 5.2 1.2 1 0 0 1 1 1 0 CRT10 RVT_1 PF00078.27 GBG64369.1 - 4.5e-28 98.3 0.0 6.5e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64369.1 - 2e-12 47.0 0.0 4.7e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64369.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG64370.1 - 2.5e-30 104.1 12.3 3.3e-07 30.9 0.1 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG64370.1 - 0.00056 20.2 0.5 0.11 12.8 0.5 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG64370.1 - 0.0066 15.2 0.1 4 6.0 0.0 3.1 2 1 0 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 GBG64370.1 - 0.031 14.3 0.0 4.5 7.4 0.0 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 GBG64370.1 - 0.27 10.5 0.0 3.9 6.7 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain rve PF00665.26 GBG64371.1 - 3.5e-12 46.6 0.0 7.8e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG64371.1 - 7.7e-10 38.7 0.0 2e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG64371.1 - 0.11 12.3 0.0 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain HAGH_C PF16123.5 GBG64371.1 - 0.43 11.1 2.2 0.76 10.3 0.8 2.1 2 0 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus DUF659 PF04937.15 GBG64372.1 - 5e-12 45.9 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64372.1 - 1.7e-07 30.9 1.1 3.1e-07 30.1 0.1 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region TFIIF_alpha PF05793.12 GBG64373.1 - 1.4 7.4 46.9 1.7 7.2 46.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 GBG64373.1 - 3.9 5.6 45.9 4.2 5.5 45.9 1.0 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 GBG64374.1 - 4.4e-40 137.7 0.0 6.7e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG64374.1 - 5.6e-37 127.4 0.0 9.2e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase U-box PF04564.15 GBG64374.1 - 2.2e-20 72.6 0.1 5.8e-20 71.2 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GBG64374.1 - 0.00011 22.0 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PIP49_C PF12260.8 GBG64374.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 zf-RING_UBOX PF13445.6 GBG64374.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger APH PF01636.23 GBG64374.1 - 0.82 9.5 6.3 1.1 9.2 3.5 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DAHP_synth_1 PF00793.20 GBG64376.1 - 2.9e-45 154.3 0.0 5.6e-21 74.6 0.0 3.3 3 0 0 3 3 3 3 DAHP synthetase I family RVP_2 PF08284.11 GBG64376.1 - 8.4e-09 35.3 0.0 2.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64376.1 - 4.3e-07 30.5 0.0 1.2e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64376.1 - 2.9e-05 24.6 0.1 0.00015 22.3 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG64376.1 - 0.0075 16.5 2.2 0.03 14.6 0.2 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein Sen15 PF09631.10 GBG64376.1 - 0.079 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Sen15 protein Asp_protease PF09668.10 GBG64376.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Adaptin_N PF01602.20 GBG64377.1 - 1.2e-138 463.0 3.1 1.6e-138 462.6 3.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 GBG64377.1 - 2.4e-21 76.1 1.5 5.9e-21 74.8 1.5 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 GBG64377.1 - 2e-08 34.5 4.2 0.00061 19.9 0.1 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GBG64377.1 - 5.5e-05 23.5 0.2 1.5 9.3 0.0 3.8 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 GBG64377.1 - 0.0035 17.5 0.7 19 5.8 0.1 4.2 3 0 0 3 3 3 2 HEAT repeat V-ATPase_H_C PF11698.8 GBG64377.1 - 0.16 12.1 0.6 1.7 8.8 0.1 2.8 2 1 0 2 2 2 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 GBG64377.1 - 0.22 12.2 0.8 6.3 7.5 0.2 2.7 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region RNase_T PF00929.24 GBG64379.1 - 2.1e-06 28.4 0.0 0.00012 22.7 0.0 2.2 2 0 0 2 2 2 1 Exonuclease zf-C2H2 PF00096.26 GBG64379.1 - 0.0038 17.6 8.3 0.77 10.3 1.2 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-MYST PF17772.1 GBG64379.1 - 0.027 14.1 1.9 2.4 7.9 0.2 2.4 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2HC_2 PF13913.6 GBG64379.1 - 0.13 12.2 10.2 0.87 9.6 0.1 3.7 3 1 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 GBG64379.1 - 0.13 12.6 1.1 2.6 8.4 1.5 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GBG64379.1 - 5.6 8.1 18.7 0.35 11.8 0.6 4.3 4 1 1 5 5 5 0 C2H2-type zinc finger RVT_1 PF00078.27 GBG64380.1 - 1e-28 100.4 0.1 1.4e-28 99.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG64380.1 - 0.025 13.7 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG64380.1 - 0.033 14.2 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG64381.1 - 6.7e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) YL1 PF05764.13 GBG64381.1 - 0.0011 19.1 9.6 0.0011 19.1 9.6 2.6 2 0 0 2 2 2 1 YL1 nuclear protein Retrotrans_gag PF03732.17 GBG64381.1 - 0.0035 17.6 0.6 0.024 14.9 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Dimer_Tnp_hAT PF05699.14 GBG64381.1 - 0.0081 15.9 0.3 0.039 13.7 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region HIP1_clath_bdg PF16515.5 GBG64381.1 - 0.0099 16.5 2.2 0.0099 16.5 2.2 4.4 5 0 0 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Asp_protease_2 PF13650.6 GBG64381.1 - 0.02 15.6 0.0 0.16 12.6 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG64381.1 - 0.038 14.5 0.0 0.14 12.7 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SPT16 PF08644.11 GBG64381.1 - 0.23 11.7 6.4 0.034 14.3 1.7 2.0 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF1818 PF08848.11 GBG64381.1 - 1.5 8.9 4.5 0.56 10.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) DUF4407 PF14362.6 GBG64381.1 - 4.9 6.4 27.3 0.054 12.8 8.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG64382.1 - 3.6e-25 88.8 0.1 5.8e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG64382.1 - 1.1e-08 35.3 0.1 2.6e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain PI3K_1B_p101 PF10486.9 GBG64384.1 - 1.6 6.4 6.0 2 6.1 6.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 GBG64384.1 - 6.2 5.3 8.4 7.6 4.9 8.4 1.0 1 0 0 1 1 1 0 Macoilin family CBF PF03914.17 GBG64385.1 - 1.1e-31 110.2 0.0 1.1e-31 110.2 0.0 3.5 3 1 1 4 4 4 1 CBF/Mak21 family Methyltransf_29 PF03141.16 GBG64386.1 - 9.7e-93 311.4 0.0 1.2e-65 222.0 0.0 2.2 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase RVT_1 PF00078.27 GBG64386.1 - 5.1e-17 62.1 0.3 8.5e-11 41.8 0.1 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG64386.1 - 4.7e-08 33.5 0.0 1.6e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64386.1 - 1.4e-07 32.0 0.0 4.1e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG64386.1 - 4.8e-07 30.0 0.0 1.4e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG64386.1 - 2.4e-06 27.4 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64386.1 - 4e-05 23.4 0.0 7.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Methyltransf_11 PF08241.12 GBG64386.1 - 7.9e-05 23.2 0.3 0.013 16.1 0.0 3.8 5 0 0 5 5 4 1 Methyltransferase domain Retrotrans_gag PF03732.17 GBG64386.1 - 0.00078 19.7 2.3 0.0052 17.0 0.1 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein Methyltransf_25 PF13649.6 GBG64386.1 - 0.0093 16.7 0.0 1.3 9.8 0.0 3.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG64386.1 - 0.038 13.8 0.0 9.6 6.0 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Chromo PF00385.24 GBG64386.1 - 0.095 12.6 0.8 0.16 11.9 0.0 1.9 2 0 0 2 2 1 0 Chromo (CHRromatin Organisation MOdifier) domain BLOC1_2 PF10046.9 GBG64386.1 - 1.2 9.5 3.1 4.8 7.6 0.5 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Methyltransf_29 PF03141.16 GBG64387.1 - 3.7e-06 25.8 0.0 5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_MLP1_2 PF07926.12 GBG64388.1 - 0.0067 16.5 4.6 0.0067 16.5 4.6 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 GBG64388.1 - 0.021 15.1 3.7 0.021 15.1 3.7 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4140 PF13600.6 GBG64388.1 - 5.2 7.6 14.8 1.6 9.2 1.3 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Asp_protease_2 PF13650.6 GBG64389.1 - 2.4e-05 24.9 0.0 5.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64389.1 - 2.6e-05 24.7 0.0 6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG64391.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) alpha-hel2 PF14456.6 GBG64391.1 - 0.19 11.0 0.2 0.3 10.4 0.2 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF150 PF02576.17 GBG64392.1 - 1.5 9.3 11.7 9.4 6.7 0.9 4.2 1 1 2 3 3 3 0 RimP N-terminal domain DUF4614 PF15391.6 GBG64393.1 - 3.7 7.5 13.3 6 6.8 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Retrotrans_gag PF03732.17 GBG64394.1 - 0.0016 18.7 0.7 0.0016 18.7 0.7 3.0 2 2 1 3 3 3 1 Retrotransposon gag protein FAM76 PF16046.5 GBG64394.1 - 0.0035 16.8 1.5 0.007 15.8 1.5 1.5 1 0 0 1 1 1 1 FAM76 protein DUF4187 PF13821.6 GBG64394.1 - 0.0046 16.7 0.8 0.02 14.7 0.8 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Vfa1 PF08432.10 GBG64394.1 - 0.9 9.8 7.5 12 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UPF0242 PF06785.11 GBG64394.1 - 2.5 8.2 10.8 5.3 7.1 10.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RasGAP_C PF03836.15 GBG64396.1 - 0.041 14.0 2.1 0.11 12.6 2.0 1.6 1 1 0 1 1 1 0 RasGAP C-terminus eIF3_subunit PF08597.10 GBG64396.1 - 0.35 10.8 3.6 0.53 10.2 3.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Casc1_N PF15927.5 GBG64396.1 - 1.3 8.6 9.5 2.6 7.7 9.5 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Amino_oxidase PF01593.24 GBG64397.1 - 1.8e-47 162.7 0.1 2.1e-47 162.5 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG64397.1 - 8.6e-10 38.7 0.1 2.8e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG64397.1 - 1.5e-05 24.7 0.1 2.4e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG64397.1 - 0.00016 20.9 0.3 0.00043 19.5 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GBG64397.1 - 0.00055 19.3 0.1 0.00099 18.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GBG64397.1 - 0.0033 16.7 1.3 0.0057 15.9 1.3 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 GBG64397.1 - 0.0047 15.7 1.9 0.0076 15.0 1.1 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GBG64397.1 - 0.0049 16.0 0.1 0.0071 15.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 GBG64397.1 - 0.033 14.8 1.6 0.088 13.4 1.6 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GBG64397.1 - 0.046 13.7 0.1 0.089 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Prenylcys_lyase PF07156.14 GBG64397.1 - 0.049 12.7 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase FAD_oxidored PF12831.7 GBG64397.1 - 0.08 12.3 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FMO-like PF00743.19 GBG64397.1 - 0.1 11.0 0.3 0.79 8.1 0.1 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.21 GBG64397.1 - 0.21 10.9 3.9 0.36 10.1 3.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.21 GBG64398.1 - 2.1e-73 247.1 0.0 2.4e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DDE_Tnp_1_6 PF13751.6 GBG64398.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Transposase DDE domain MTBP_mid PF14919.6 GBG64398.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding RT_RNaseH_2 PF17919.1 GBG64399.1 - 9.5e-31 105.8 0.0 2e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64399.1 - 2.1e-18 66.5 0.0 4.8e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2730 PF10805.8 GBG64400.1 - 0.013 15.6 0.2 0.033 14.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) TolA_bind_tri PF16331.5 GBG64400.1 - 0.04 14.0 2.2 0.04 14.0 2.2 2.5 2 1 0 2 2 2 0 TolA binding protein trimerisation SlyX PF04102.12 GBG64400.1 - 0.083 13.5 0.8 0.083 13.5 0.8 3.9 2 2 2 4 4 4 0 SlyX Filament PF00038.21 GBG64400.1 - 0.67 9.5 14.8 0.59 9.7 10.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein RVP_2 PF08284.11 GBG64401.1 - 1.4e-05 24.9 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64401.1 - 3.2e-05 24.4 0.2 7.2e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64401.1 - 0.00028 21.5 0.0 0.00067 20.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64401.1 - 0.0006 19.6 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Casc1_N PF15927.5 GBG64402.1 - 0.013 15.2 11.9 0.013 15.2 11.9 3.3 2 1 1 3 3 3 0 Cancer susceptibility candidate 1 N-terminus OrfB_IS605 PF01385.19 GBG64402.1 - 2.4 8.4 14.5 1.2 9.4 1.7 3.0 3 1 0 3 3 3 0 Probable transposase Integrase_H2C2 PF17921.1 GBG64403.1 - 2.4e-12 46.8 0.2 7.7e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG64403.1 - 8.5e-07 29.2 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64403.1 - 0.0004 20.5 0.0 0.00088 19.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG64403.1 - 0.011 16.0 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein DUF2615 PF11027.8 GBG64404.1 - 0.0001 22.4 4.2 0.00013 22.0 3.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2615) Orf78 PF06024.12 GBG64404.1 - 0.017 15.4 1.5 0.017 15.4 1.5 2.1 1 1 1 2 2 2 0 Orf78 (ac78) SDA1 PF05285.12 GBG64404.1 - 0.025 14.0 29.3 0.029 13.8 29.3 1.0 1 0 0 1 1 1 0 SDA1 ABC2_membrane_3 PF12698.7 GBG64404.1 - 0.029 13.5 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF898 PF05987.13 GBG64404.1 - 0.089 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) SARAF PF06682.12 GBG64404.1 - 0.13 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis FixH PF05751.11 GBG64404.1 - 0.25 11.3 1.2 0.46 10.5 1.2 1.3 1 0 0 1 1 1 0 FixH DUF1676 PF07898.13 GBG64404.1 - 0.42 10.6 15.3 0.062 13.3 11.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1676) EMC3_TMCO1 PF01956.16 GBG64404.1 - 0.53 10.0 12.8 0.7 9.6 12.8 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Afi1 PF07792.12 GBG64404.1 - 3.4 8.1 18.3 0.95 9.9 3.5 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Conotoxin PF02950.17 GBG64404.1 - 3.9 8.6 10.0 0.16 13.0 2.3 2.4 1 1 1 2 2 2 0 Conotoxin NOA36 PF06524.12 GBG64404.1 - 5.8 6.1 46.4 0.27 10.5 18.7 2.1 2 0 0 2 2 2 0 NOA36 protein Serinc PF03348.15 GBG64404.1 - 5.8 5.7 8.6 1.9 7.3 6.1 1.5 1 1 1 2 2 2 0 Serine incorporator (Serinc) DUF659 PF04937.15 GBG64405.1 - 3e-06 27.1 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ArfGap PF01412.18 GBG64406.1 - 8e-37 125.9 0.0 1.7e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RT_RNaseH_2 PF17919.1 GBG64407.1 - 1.8e-17 63.2 0.0 5.1e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64407.1 - 3.8e-08 33.6 0.0 1.1e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64407.1 - 0.00016 21.2 0.2 0.00031 20.3 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) REV PF00424.18 GBG64407.1 - 0.073 13.1 0.7 0.27 11.3 0.4 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) RE_AlwI PF09491.10 GBG64407.1 - 0.15 10.9 2.5 0.27 10.0 2.5 1.4 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF3138 PF11336.8 GBG64407.1 - 0.52 8.9 2.4 0.84 8.2 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PA26 PF04636.13 GBG64407.1 - 0.57 9.0 9.6 0.81 8.5 9.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF5401 PF17380.2 GBG64407.1 - 3.4 5.6 19.0 5.3 5.0 19.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) TssO PF17561.2 GBG64407.1 - 4.5 7.4 7.2 10 6.2 7.2 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO Lin-8 PF03353.15 GBG64408.1 - 3 7.3 12.5 4.9 6.6 12.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Orai-1 PF07856.12 GBG64409.1 - 0.0068 16.1 0.2 0.008 15.9 0.2 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity gag-asp_proteas PF13975.6 GBG64412.1 - 0.00019 21.9 0.1 0.00052 20.5 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64412.1 - 0.011 16.3 0.0 0.027 15.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG64412.1 - 0.014 15.7 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1998 PF09369.10 GBG64412.1 - 0.037 14.8 0.1 0.037 14.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1998) ADIP PF11559.8 GBG64412.1 - 6.5 6.8 8.7 13 5.9 8.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Abhydrolase_1 PF00561.20 GBG64413.1 - 1.2e-13 51.3 0.2 1.8e-09 37.6 0.1 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG64413.1 - 4.9e-07 30.6 2.6 0.0012 19.5 1.0 2.6 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG64413.1 - 4.8e-05 22.7 0.0 0.0061 15.9 0.0 2.6 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Retrotrans_gag PF03732.17 GBG64413.1 - 0.00012 22.3 2.5 0.00056 20.1 0.1 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein Abhydrolase_4 PF08386.10 GBG64413.1 - 0.00084 19.4 0.0 0.0049 16.9 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein HIP1_clath_bdg PF16515.5 GBG64413.1 - 0.052 14.2 3.7 0.078 13.6 1.3 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Integrase_H2C2 PF17921.1 GBG64415.1 - 4.6e-18 65.1 1.4 1.3e-17 63.7 1.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG64415.1 - 3.1e-16 59.6 0.0 9.3e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64415.1 - 1.6e-15 57.3 0.0 3.7e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG64415.1 - 2.9e-13 49.7 0.0 8.8e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG64415.1 - 0.5 10.5 1.9 1.5 9.0 1.9 1.9 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG64416.1 - 1.9e-17 63.6 0.1 4.2e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG64417.1 - 2.3e-30 105.8 0.1 4.2e-30 104.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64417.1 - 5.9e-29 100.1 0.0 3.3e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64417.1 - 1.4e-26 92.8 0.0 2.9e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64417.1 - 7.1e-14 52.0 0.0 2.4e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG64417.1 - 6.6e-11 42.0 0.0 1.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2203 PF09969.9 GBG64418.1 - 0.052 14.3 0.6 0.8 10.4 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3391 PF11871.8 GBG64418.1 - 0.16 12.5 0.6 3.8 8.1 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) DUF659 PF04937.15 GBG64421.1 - 2.2e-16 60.0 0.0 4.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG64422.1 - 4e-07 30.3 0.0 7.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64422.1 - 4.6e-06 26.6 0.0 9.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG64422.1 - 0.00057 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64422.1 - 0.00063 20.2 0.0 0.0017 18.9 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG64422.1 - 0.0026 18.1 0.1 0.0054 17.0 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64422.1 - 0.0044 16.8 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG64423.1 - 1.3e-05 25.5 0.4 3e-05 24.3 0.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG64425.1 - 2.2e-15 56.7 0.6 8.7e-15 54.7 0.0 2.2 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64425.1 - 1.3e-07 31.4 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG64425.1 - 0.0083 15.8 0.1 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG64426.1 - 0.00019 21.8 2.5 0.00061 20.1 0.3 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG64426.1 - 0.18 12.1 1.0 8.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Cellulase PF00150.18 GBG64427.1 - 2.2e-06 27.3 0.0 4.1e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 GBG64427.1 - 0.0083 15.8 0.0 0.04 13.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4038) DUF4787 PF16029.5 GBG64428.1 - 9.9e-20 70.4 1.3 9.9e-20 70.4 1.3 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4787) UCR_hinge PF02320.16 GBG64428.1 - 0.0033 17.6 0.6 0.0076 16.4 0.6 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Myc_N PF01056.18 GBG64428.1 - 0.016 15.1 0.5 0.018 15.0 0.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region HpaB_N PF11794.8 GBG64428.1 - 0.17 11.5 0.5 0.27 10.9 0.5 1.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal zf-CCHC PF00098.23 GBG64431.1 - 3.9e-07 29.8 2.0 8.1e-07 28.8 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Ins134_P3_kin_N PF17927.1 GBG64431.1 - 0.035 14.5 0.1 0.1 13.0 0.1 1.7 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain PH_12 PF16457.5 GBG64431.1 - 0.05 14.1 2.4 0.44 11.1 0.0 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain DUF4778 PF16008.5 GBG64431.1 - 0.051 13.6 8.7 0.071 13.2 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Fzo_mitofusin PF04799.13 GBG64431.1 - 0.076 12.6 7.3 0.86 9.1 0.1 2.2 2 0 0 2 2 2 0 fzo-like conserved region RT_RNaseH PF17917.1 GBG64435.1 - 6.7e-25 87.4 0.0 1.1e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64435.1 - 2e-23 82.3 0.0 3.4e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64435.1 - 4.8e-09 36.0 0.1 8.3e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrin_b_cyt PF08725.11 GBG64435.1 - 0.047 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RVT_3 PF13456.6 GBG64435.1 - 0.059 13.2 0.0 0.15 11.8 0.0 1.8 1 1 0 1 1 1 0 Reverse transcriptase-like zf-CCHC PF00098.23 GBG64437.1 - 4.6e-08 32.8 1.3 1.1e-07 31.6 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG64437.1 - 0.0021 17.8 2.8 0.073 12.9 0.6 2.5 2 0 0 2 2 2 1 Zinc knuckle DUF1192 PF06698.11 GBG64437.1 - 0.004 17.2 1.1 0.011 15.7 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Endonuc-dimeris PF09124.10 GBG64437.1 - 0.052 13.7 0.4 1.1 9.5 0.0 2.4 2 1 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation zf-CCHC_3 PF13917.6 GBG64437.1 - 0.096 12.7 0.4 0.23 11.5 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Inj_translocase PF16928.5 GBG64437.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome TPR_2 PF07719.17 GBG64438.1 - 3.9e-07 29.7 0.1 8.5e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG64438.1 - 4.9e-07 29.3 0.1 8.7e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG64438.1 - 9e-06 25.3 0.3 4.1e-05 23.2 0.3 1.9 1 1 1 2 2 2 1 TPR repeat TPR_8 PF13181.6 GBG64438.1 - 1.1e-05 25.2 1.0 2e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG64438.1 - 0.0026 17.7 0.1 0.0056 16.6 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG64438.1 - 0.042 14.7 0.0 0.071 14.0 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG64438.1 - 0.1 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DDE_Tnp_4 PF13359.6 GBG64439.1 - 1.2e-26 93.3 0.0 1.7e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64439.1 - 9.6e-14 51.5 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG64439.1 - 1.4e-05 24.9 0.2 0.051 13.2 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG64440.1 - 6.8e-31 106.3 0.0 8.9e-30 102.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64440.1 - 9.9e-31 106.1 0.3 2.4e-29 101.7 0.1 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64440.1 - 2.7e-19 69.0 0.4 6.6e-19 67.8 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64440.1 - 2.8e-13 50.1 0.0 9.1e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64440.1 - 0.0023 18.1 0.0 0.0076 16.4 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG64440.1 - 0.24 11.0 0.0 0.24 11.0 0.0 3.0 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase TadF PF16964.5 GBG64440.1 - 0.25 11.1 1.4 0.6 9.9 1.4 1.6 1 0 0 1 1 1 0 Putative tight adherence pilin protein F Peptidase_A17 PF05380.13 GBG64440.1 - 0.58 10.1 3.6 25 4.8 0.0 3.1 2 1 1 3 3 3 0 Pao retrotransposon peptidase Es2 PF09751.9 GBG64440.1 - 0.74 9.5 13.4 0.24 11.1 10.6 1.5 2 0 0 2 2 2 0 Nuclear protein Es2 LMBR1 PF04791.16 GBG64440.1 - 1.6 7.5 6.4 0.17 10.8 2.1 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein TerB_C PF15615.6 GBG64440.1 - 9.6 6.5 16.8 0.75 10.1 11.8 1.7 2 0 0 2 2 2 0 TerB-C domain DUF3915 PF13054.6 GBG64442.1 - 0.0026 17.7 0.6 0.0041 17.1 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 GBG64442.1 - 0.11 10.8 15.6 0.042 12.2 13.1 1.5 1 1 0 1 1 1 0 Atrophin-1 family PAS_9 PF13426.7 GBG64443.1 - 5.7e-22 77.9 0.0 1.2e-21 76.9 0.0 1.5 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 GBG64443.1 - 8.3e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 GBG64443.1 - 5.9e-08 32.7 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 GBG64443.1 - 5.7e-05 23.3 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold RVT_1 PF00078.27 GBG64444.1 - 4.3e-25 88.5 0.1 7.9e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG64444.1 - 4e-08 33.5 0.1 1.5e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG64444.1 - 0.0012 19.1 0.1 0.0071 16.6 0.1 2.4 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.24 GBG64444.1 - 0.022 14.7 0.1 0.055 13.4 0.1 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 GBG64444.1 - 0.034 14.7 0.0 0.16 12.6 0.0 2.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64444.1 - 0.071 13.8 0.0 0.33 11.6 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease PAS_9 PF13426.7 GBG64445.1 - 1.7e-06 28.2 0.0 4e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 GBG64445.1 - 0.018 15.1 0.0 0.085 12.9 0.0 1.9 2 0 0 2 2 2 0 PAS fold DUF4195 PF13836.6 GBG64445.1 - 0.08 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) LMWSLP_N PF12211.8 GBG64445.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal PAS_3 PF08447.12 GBG64445.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.25 GBG64446.1 - 1.5e-14 54.1 0.0 2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG64446.1 - 1.1e-06 28.1 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S7 PF00177.21 GBG64447.1 - 1.6e-37 128.4 2.3 2e-37 128.1 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_L6e PF01159.19 GBG64447.1 - 0.11 13.1 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e FPP PF05911.11 GBG64449.1 - 8.3e-08 30.9 47.1 2.8e-07 29.2 21.5 7.2 3 3 3 7 7 7 4 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 GBG64449.1 - 0.23 11.9 179.5 1.3 9.4 20.5 9.3 2 2 8 10 10 10 0 Fez1 FPP PF05911.11 GBG64450.1 - 5.7e-08 31.5 46.8 2.6e-07 29.3 21.5 7.2 3 3 3 7 7 7 4 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 GBG64450.1 - 0.1 13.0 178.7 2.1 8.8 10.9 9.2 2 2 8 10 10 10 0 Fez1 Retrotrans_gag PF03732.17 GBG64451.1 - 0.0088 16.3 0.4 0.016 15.5 0.4 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein alpha-hel2 PF14456.6 GBG64451.1 - 0.051 12.9 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF659 PF04937.15 GBG64452.1 - 2.9e-13 49.9 0.0 4.6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64452.1 - 0.0065 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RRM_1 PF00076.22 GBG64454.1 - 2e-19 69.2 0.0 4.2e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_14 PF13428.6 GBG64454.1 - 0.00014 22.4 12.7 0.11 13.4 0.3 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat Suf PF05843.14 GBG64454.1 - 0.016 15.2 0.0 19 5.1 0.0 3.9 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) DUF2052 PF09747.9 GBG64454.1 - 0.47 10.5 12.3 0.055 13.6 0.5 2.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Myc_N PF01056.18 GBG64454.1 - 3.8 7.3 5.9 0.25 11.2 0.2 1.8 2 0 0 2 2 2 0 Myc amino-terminal region Sarcoglycan_1 PF04790.13 GBG64455.1 - 0.27 10.5 2.5 0.47 9.8 2.5 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein RT_RNaseH_2 PF17919.1 GBG64458.1 - 5.9e-31 106.5 0.1 2.2e-30 104.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64458.1 - 1.7e-30 105.4 0.0 3.9e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ANAPC5 PF12862.7 GBG64458.1 - 8.9e-27 93.0 1.1 8.9e-16 57.7 0.1 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 5 RVT_1 PF00078.27 GBG64458.1 - 1.3e-12 47.7 0.1 2.6e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRAPPC9-Trs120 PF08626.11 GBG64458.1 - 0.0064 13.9 0.0 0.0096 13.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Phage_lysozyme PF00959.19 GBG64458.1 - 0.1 13.1 0.0 0.6 10.6 0.0 2.4 1 0 0 1 1 1 0 Phage lysozyme gpUL132 PF11359.8 GBG64458.1 - 0.2 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 TPR_16 PF13432.6 GBG64458.1 - 4 8.2 18.6 11 6.7 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF507 PF04368.13 GBG64459.1 - 0.04 13.9 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF507) PMM PF03332.13 GBG64460.1 - 2.6e-109 364.2 0.5 3e-109 363.9 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 GBG64460.1 - 4.9e-08 33.0 0.1 1.2e-07 31.7 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GBG64460.1 - 0.00073 19.1 0.0 0.73 9.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Molybdopterin PF00384.22 GBG64462.1 - 6.3e-19 68.2 0.0 1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 GBG64462.1 - 3.2e-17 62.9 0.0 6.1e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Pkinase PF00069.25 GBG64463.1 - 8.4e-51 172.9 0.0 1.1e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG64463.1 - 1e-26 93.8 0.0 1.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG64463.1 - 9.2e-06 25.2 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GBG64463.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FA_desaturase PF00487.24 GBG64463.1 - 0.34 10.7 2.7 0.56 10.0 2.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Spt20 PF12090.8 GBG64463.1 - 9.9 5.7 8.9 20 4.7 8.9 1.4 1 0 0 1 1 1 0 Spt20 family RVT_1 PF00078.27 GBG64464.1 - 1.4e-12 47.6 0.0 6.1e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG64464.1 - 0.0014 18.2 0.2 0.006 16.1 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DHC_N2 PF08393.13 GBG64465.1 - 3.9e-09 36.1 2.3 4.1e-09 36.0 0.3 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 GBG64465.1 - 9.8e-09 34.4 0.0 2.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DIRP PF06584.13 GBG64465.1 - 0.012 15.7 0.8 0.061 13.5 0.3 2.4 2 0 0 2 2 2 0 DIRP CDC45 PF02724.14 GBG64466.1 - 6e-05 21.5 13.4 8.9e-05 21.0 13.4 1.1 1 0 0 1 1 1 1 CDC45-like protein BSP_II PF05432.11 GBG64466.1 - 0.0037 17.0 19.0 0.007 16.1 19.0 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) B12-binding PF02310.19 GBG64466.1 - 0.055 13.5 0.1 0.25 11.4 0.0 2.1 3 0 0 3 3 2 0 B12 binding domain CCDC106 PF15794.5 GBG64466.1 - 0.075 12.7 8.8 0.12 12.0 8.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Period_C PF12114.8 GBG64466.1 - 0.8 9.3 9.3 0.75 9.4 8.0 1.5 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DUF2052 PF09747.9 GBG64466.1 - 2 8.5 21.5 4.2 7.5 21.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Dsh_C PF12316.8 GBG64466.1 - 2.1 8.7 9.0 4.4 7.7 9.0 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Nop14 PF04147.12 GBG64466.1 - 3 6.0 24.6 4.2 5.5 24.6 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG64466.1 - 3 6.2 26.6 4.4 5.6 26.6 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 GBG64466.1 - 3 7.1 27.3 4.7 6.5 27.3 1.1 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 GBG64466.1 - 4 7.2 13.8 7.1 6.4 13.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 GBG64466.1 - 4.4 6.1 10.7 6.8 5.4 10.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF913 PF06025.12 GBG64466.1 - 6 5.7 4.8 11 4.8 4.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.6 GBG64466.1 - 9.2 6.1 13.4 20 5.1 13.4 1.5 1 0 0 1 1 1 0 Spore coat protein CotO TAXi_N PF14543.6 GBG64467.1 - 2e-16 60.8 0.2 2e-16 60.8 0.2 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GBG64467.1 - 5.7e-05 22.9 0.0 0.00018 21.3 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 GBG64467.1 - 0.00075 19.0 0.0 0.0013 18.2 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GBG64468.1 - 7.4e-15 55.6 1.2 7.4e-15 55.6 1.2 2.2 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GBG64468.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Lysis_col PF02402.16 GBG64468.1 - 5.3 6.8 9.3 0.84 9.4 0.7 3.6 2 0 0 2 2 2 0 Lysis protein TAXi_N PF14543.6 GBG64469.1 - 1.4e-17 64.5 0.2 1.4e-17 64.5 0.2 3.5 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GBG64469.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal CDC45 PF02724.14 GBG64469.1 - 1.4 7.1 3.1 2.1 6.6 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TAXi_N PF14543.6 GBG64470.1 - 4.2e-11 43.4 0.2 8.7e-11 42.4 0.1 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GBG64470.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.7 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal PDCD7 PF16021.5 GBG64471.1 - 1.2e-12 47.6 1.6 1.2e-12 47.6 1.6 3.4 2 1 1 3 3 3 2 Programmed cell death protein 7 3HBOH PF10605.9 GBG64472.1 - 0.041 12.1 0.0 0.064 11.5 0.0 1.2 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Pol_alpha_B_N PF08418.10 GBG64472.1 - 0.58 10.1 8.9 2.5 8.0 8.9 1.9 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fer4_16 PF13484.6 GBG64472.1 - 3.2 8.8 5.4 5.4 8.0 0.4 2.8 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain betaPIX_CC PF16523.5 GBG64472.1 - 8.3 6.3 21.3 2.2 8.2 5.1 3.3 2 1 1 3 3 3 0 betaPIX coiled coil Yippee-Mis18 PF03226.14 GBG64474.1 - 6.1e-15 55.3 1.7 7.3e-15 55.1 1.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Jas PF16135.5 GBG64474.1 - 0.011 15.9 0.9 0.019 15.1 0.9 1.5 1 1 0 1 1 1 0 TPL-binding domain in jasmonate signalling Evr1_Alr PF04777.13 GBG64474.1 - 0.076 13.5 1.2 0.15 12.5 0.1 1.9 1 1 1 2 2 2 0 Erv1 / Alr family RIG-I_C-RD PF11648.8 GBG64474.1 - 0.077 13.2 2.5 0.11 12.8 2.5 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I RVT_1 PF00078.27 GBG64475.1 - 6.1e-24 84.8 0.8 1.3e-23 83.7 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64475.1 - 6.6e-08 32.4 0.0 1.8e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64475.1 - 1.5e-06 28.8 0.0 3.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64475.1 - 0.00023 21.6 0.0 0.00059 20.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG64475.1 - 0.0014 18.9 0.5 0.012 15.9 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG64475.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4187 PF13821.6 GBG64475.1 - 0.28 11.0 5.1 0.075 12.8 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) PTCB-BRCT PF12738.7 GBG64476.1 - 4.1e-16 58.7 0.4 8.1e-16 57.7 0.4 1.5 1 0 0 1 1 1 1 twin BRCT domain PHD PF00628.29 GBG64476.1 - 1.9e-09 37.3 3.8 1.9e-09 37.3 3.8 3.6 3 1 0 3 3 2 1 PHD-finger BRCT PF00533.26 GBG64476.1 - 1.4e-08 34.9 0.0 3.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-RING_2 PF13639.6 GBG64476.1 - 6.6e-06 26.4 11.3 6.6e-06 26.4 11.3 3.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 GBG64476.1 - 2e-05 24.4 11.1 2e-05 24.4 11.1 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG64476.1 - 3.5e-05 23.6 7.3 3.5e-05 23.6 7.3 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) BRCT_2 PF16589.5 GBG64476.1 - 0.00027 21.3 0.0 0.00059 20.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain zf-rbx1 PF12678.7 GBG64476.1 - 0.00034 20.8 6.9 0.00034 20.8 6.9 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain FHA_2 PF17913.1 GBG64476.1 - 0.0016 18.6 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 GBG64476.1 - 0.25 11.1 6.3 1.2 9.0 6.3 2.3 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 GBG64476.1 - 0.34 11.1 9.9 1.8 8.8 9.9 2.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GBG64476.1 - 1.3 9.0 19.9 0.026 14.3 11.2 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 GBG64476.1 - 1.9 8.3 8.2 8.2 6.3 8.2 2.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 GBG64476.1 - 3.7 7.5 12.5 0.086 12.8 5.0 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 GBG64476.1 - 3.8 7.6 9.8 0.09 12.8 2.5 2.1 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PEPCK_ATP PF01293.20 GBG64478.1 - 7.8e-213 707.3 0.0 9.2e-213 707.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 GBG64478.1 - 0.046 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DDE_Tnp_4 PF13359.6 GBG64479.1 - 2.1e-16 60.0 0.0 1.7e-15 57.0 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64479.1 - 4.4e-07 29.7 0.0 7.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG64479.1 - 0.033 13.8 0.0 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 Transposase DDE domain PEPCK_ATP PF01293.20 GBG64481.1 - 2.8e-214 712.1 0.0 3.3e-214 711.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 GBG64481.1 - 0.045 13.5 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 GBG64482.1 - 3.9e-212 705.0 0.0 4.5e-212 704.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 GBG64482.1 - 0.15 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 GBG64483.1 - 8e-212 704.0 0.0 9.3e-212 703.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 GBG64483.1 - 0.15 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 GBG64484.1 - 5.4e-27 94.7 0.0 1.1e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.24 GBG64484.1 - 1.1e-12 48.5 0.1 1.1e-12 48.5 0.1 4.2 4 0 0 4 4 4 1 Core histone H2A/H2B/H3/H4 DUF2695 PF10905.8 GBG64484.1 - 0.0017 18.5 0.0 4.8 7.5 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2695) PEPCK_ATP PF01293.20 GBG64485.1 - 1.9e-67 227.9 0.0 1.8e-54 185.2 0.0 2.0 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.20 GBG64486.1 - 3.3e-213 708.5 0.0 4e-213 708.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Aa_trans PF01490.18 GBG64486.1 - 5.4e-48 163.7 24.7 9.7e-30 103.6 15.7 2.4 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein AAA_24 PF13479.6 GBG64486.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.18 GBG64487.1 - 4.5e-55 187.0 17.6 1.2e-35 123.0 8.5 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein PEPCK_ATP PF01293.20 GBG64488.1 - 3e-212 705.4 0.0 3.5e-212 705.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 GBG64488.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 GBG64489.1 - 4.2e-211 701.6 0.0 5e-211 701.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 GBG64489.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 GBG64491.1 - 1.1e-36 126.4 0.1 1.9e-36 125.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64491.1 - 8.3e-31 106.0 0.0 3.5e-30 104.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64491.1 - 1.1e-30 106.0 0.4 4.1e-30 104.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64492.1 - 7.9e-25 86.8 0.0 1.4e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64492.1 - 9.6e-23 80.5 0.0 1.8e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64492.1 - 2e-16 59.8 0.6 1.5e-15 57.0 0.2 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG64492.1 - 1.1e-11 45.0 0.0 2.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG64492.1 - 1.9e-09 37.4 0.1 3.1e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG64492.1 - 0.00083 19.2 0.1 0.0018 18.1 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG64492.1 - 0.0022 18.2 0.1 0.0053 17.0 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF4355 PF14265.6 GBG64493.1 - 0.011 15.9 9.1 0.011 15.9 9.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) Eno-Rase_FAD_bd PF07055.12 GBG64493.1 - 1.1 9.7 7.3 1.6e+02 2.8 7.3 2.9 1 1 0 1 1 1 0 Enoyl reductase FAD binding domain FapA PF03961.13 GBG64493.1 - 4.1 5.9 16.9 11 4.5 16.8 1.7 1 1 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 GBG64493.1 - 7.2 5.4 8.9 7.9 5.3 8.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RT_RNaseH PF17917.1 GBG64494.1 - 1.8e-19 69.9 0.1 4.6e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64494.1 - 6.1e-19 67.9 0.0 1.2e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64494.1 - 6.1e-11 42.3 0.7 2.2e-10 40.4 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrin_b_cyt PF08725.11 GBG64494.1 - 0.0029 17.3 0.1 0.0077 15.9 0.1 1.8 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain APG17 PF04108.12 GBG64494.1 - 0.011 14.8 0.1 0.019 14.1 0.1 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 DDE_Tnp_4 PF13359.6 GBG64496.1 - 3.4e-17 62.6 0.0 1.6e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64496.1 - 1.2e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG64497.1 - 0.00051 20.4 0.1 0.0012 19.2 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG64498.1 - 5.1e-11 42.7 0.0 9.9e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64498.1 - 4.2e-06 26.5 1.2 7.3e-05 22.5 0.2 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region CAAX_1 PF15895.5 GBG64498.1 - 0.15 12.0 0.8 7.6 6.4 0.3 2.3 2 0 0 2 2 2 0 CAAX box cerebral protein 1 RT_RNaseH_2 PF17919.1 GBG64499.1 - 2.1e-28 98.3 0.0 4.5e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64499.1 - 6.6e-25 87.4 0.0 1.3e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AAA PF00004.29 GBG64499.1 - 1.6e-18 67.4 0.0 4.7e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RVT_1 PF00078.27 GBG64499.1 - 5.1e-13 49.1 0.0 8.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BCS1_N PF08740.11 GBG64499.1 - 7.3e-13 48.9 0.1 2.1e-12 47.4 0.1 1.9 1 0 0 1 1 1 1 BCS1 N terminal DUF815 PF05673.13 GBG64499.1 - 0.0026 17.0 4.4 0.0035 16.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 GBG64499.1 - 0.079 12.7 0.0 0.079 12.7 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 GBG64499.1 - 0.21 12.0 3.7 0.52 10.7 0.1 3.2 3 1 1 4 4 4 0 AAA ATPase domain Myb_DNA-bind_4 PF13837.6 GBG64501.1 - 0.00027 21.2 4.5 0.00055 20.3 4.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG64501.1 - 0.00051 20.1 3.6 0.00097 19.2 3.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain gag-asp_proteas PF13975.6 GBG64502.1 - 0.0001 22.8 0.1 0.00028 21.4 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64502.1 - 0.0028 18.2 0.2 0.0093 16.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG64502.1 - 0.0086 15.9 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG64502.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG64502.1 - 0.023 14.4 0.1 0.043 13.5 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Polyketide_cyc2 PF10604.9 GBG64502.1 - 0.091 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF659 PF04937.15 GBG64503.1 - 5.8e-33 113.9 0.1 9e-33 113.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG64504.1 - 0.23 11.9 0.2 0.23 11.9 0.2 2.9 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain GF_recep_IV PF14843.6 GBG64504.1 - 4.5 7.1 10.0 10 5.9 0.8 2.4 2 0 0 2 2 2 0 Growth factor receptor domain IV Rho_N PF07498.12 GBG64505.1 - 0.0091 15.9 0.4 0.018 15.0 0.4 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Carmo_coat_C PF08462.10 GBG64505.1 - 0.016 15.3 0.2 0.084 13.0 0.0 2.3 3 0 0 3 3 3 0 Carmovirus coat protein SAP PF02037.27 GBG64505.1 - 0.018 14.8 0.3 0.037 13.8 0.3 1.5 1 0 0 1 1 1 0 SAP domain DUF2510 PF10708.9 GBG64506.1 - 8.9 6.2 9.2 2.1 8.2 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2510) rve PF00665.26 GBG64507.1 - 4.3e-08 33.4 0.0 1.1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG64507.1 - 0.57 10.5 10.3 0.36 11.1 0.2 3.8 3 1 0 3 3 3 0 Retrotransposon gag protein BLOC1_2 PF10046.9 GBG64507.1 - 0.6 10.4 7.4 0.14 12.5 3.5 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-CCHC PF00098.23 GBG64508.1 - 2.2e-08 33.8 2.3 3.8e-08 33.0 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG64508.1 - 0.012 15.3 0.9 0.023 14.4 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG64508.1 - 0.063 13.1 0.6 0.13 12.1 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG64508.1 - 0.092 12.7 0.2 0.092 12.7 0.2 2.0 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG64508.1 - 0.1 12.5 2.2 0.17 11.7 2.2 1.4 1 0 0 1 1 1 0 Zinc knuckle PEARLI-4 PF05278.12 GBG64508.1 - 0.25 10.9 7.0 0.32 10.5 7.0 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) FYDLN_acid PF09538.10 GBG64508.1 - 5.3 7.8 12.6 3.9 8.2 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) GRP PF07172.11 GBG64510.1 - 0.18 12.5 17.2 0.65 10.7 17.2 1.9 1 0 0 1 1 1 0 Glycine rich protein family Myb_DNA-bind_4 PF13837.6 GBG64512.1 - 6.9e-05 23.2 5.2 0.0001 22.6 3.1 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG64512.1 - 0.055 13.8 3.5 0.39 11.0 1.3 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MAP17 PF15807.5 GBG64512.1 - 0.082 13.1 0.9 0.18 12.0 0.0 2.0 2 1 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Comm PF15957.5 GBG64512.1 - 0.22 11.9 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Commissureless RVT_1 PF00078.27 GBG64514.1 - 6.8e-29 101.0 0.0 1.2e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG64514.1 - 2e-05 25.1 0.0 5.8e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64514.1 - 0.00014 22.4 0.0 0.00044 20.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG64514.1 - 0.00042 20.1 0.0 0.00096 18.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64514.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease HycH PF07450.11 GBG64514.1 - 0.073 13.4 0.9 0.2 12.0 0.9 1.7 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH GSHPx PF00255.19 GBG64514.1 - 0.075 12.6 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione peroxidase DUF5095 PF17016.5 GBG64514.1 - 0.28 10.8 3.9 4.4 6.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5095) COMP PF11598.8 GBG64514.1 - 5.7 7.5 5.4 1.5 9.4 0.6 2.4 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Adaptin_binding PF10199.9 GBG64514.1 - 7.8 7.1 10.8 4.1 8.0 6.3 2.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RT_RNaseH_2 PF17919.1 GBG64515.1 - 1.3e-29 102.2 0.0 3.6e-29 100.8 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64515.1 - 1.4e-29 102.5 0.2 3.1e-29 101.4 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64515.1 - 9e-15 54.5 0.1 2.4e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG64515.1 - 2.6e-10 40.2 0.0 5.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG64515.1 - 0.036 14.3 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG64515.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase NB-ARC PF00931.22 GBG64516.1 - 2.1e-37 128.7 0.0 6e-37 127.2 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 GBG64516.1 - 0.032 14.6 3.9 0.057 13.8 0.1 3.0 3 1 0 3 3 3 0 AAA ATPase domain CLIP_SPH_Scar PF18399.1 GBG64518.1 - 0.014 15.5 0.5 0.02 15.0 0.5 1.2 1 0 0 1 1 1 0 Clip-domain serine protease homolog Scarface RT_RNaseH_2 PF17919.1 GBG64520.1 - 1.3e-28 99.0 0.0 2.9e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64520.1 - 9.4e-25 86.9 0.0 1.9e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64520.1 - 8.6e-15 54.8 0.1 1.4e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3807 PF12720.7 GBG64520.1 - 0.56 10.5 14.8 0.9 9.8 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Nop14 PF04147.12 GBG64520.1 - 1.3 7.2 21.5 2.1 6.5 21.5 1.2 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 GBG64520.1 - 1.3 9.3 14.4 2.3 8.5 14.4 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 GBG64520.1 - 5.5 6.2 25.7 8 5.7 25.7 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG64520.1 - 7.2 5.9 26.9 11 5.3 26.9 1.2 1 0 0 1 1 1 0 SDA1 DUF4746 PF15928.5 GBG64520.1 - 8.6 5.7 15.3 15 4.9 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Patatin PF01734.22 GBG64521.1 - 2.2e-12 47.6 2.3 9.6e-12 45.5 2.3 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase SPX PF03105.19 GBG64521.1 - 0.92 9.4 3.0 1.4 8.8 3.0 1.2 1 0 0 1 1 1 0 SPX domain Mito_fiss_reg PF05308.11 GBG64521.1 - 6.7 6.7 14.3 13 5.8 14.3 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Peptidase_M1 PF01433.20 GBG64522.1 - 3e-40 138.1 0.0 5.4e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 GBG64522.1 - 5.2e-24 84.5 0.0 8.4e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 GBG64522.1 - 1.3e-12 48.3 0.0 2.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 GBG64522.1 - 0.00094 18.9 0.1 0.0024 17.6 0.1 1.6 2 0 0 2 2 2 1 Peptidase MA superfamily Peptidase_M61 PF05299.12 GBG64522.1 - 0.012 15.9 1.0 0.18 12.2 1.0 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_M48 PF01435.18 GBG64522.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 Aminopep PF10023.9 GBG64522.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative aminopeptidase Peptidase_C14 PF00656.22 GBG64523.1 - 5.5e-53 180.5 0.0 1.6e-52 179.0 0.0 1.7 1 1 0 1 1 1 1 Caspase domain zf-LSD1 PF06943.12 GBG64523.1 - 3.7e-06 26.7 4.7 1e-05 25.3 4.7 1.8 1 0 0 1 1 1 1 LSD1 zinc finger Raptor_N PF14538.6 GBG64523.1 - 0.08 12.9 0.9 1 9.3 0.0 2.6 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain zf-LSD1 PF06943.12 GBG64524.1 - 9.2e-05 22.2 1.5 0.00021 21.0 1.5 1.7 1 0 0 1 1 1 1 LSD1 zinc finger zinc_ribbon_12 PF11331.8 GBG64524.1 - 0.00056 19.7 2.1 0.0023 17.7 2.1 1.9 1 1 0 1 1 1 1 Probable zinc-ribbon domain zinc_ribbon_4 PF13717.6 GBG64524.1 - 0.014 15.3 2.6 0.15 12.0 2.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-rbx1 PF12678.7 GBG64524.1 - 0.039 14.2 0.9 0.068 13.5 0.9 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 GBG64524.1 - 0.046 13.6 1.8 0.068 13.1 1.8 1.3 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 GBG64524.1 - 0.051 13.2 2.0 0.073 12.7 2.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rpr2 PF04032.16 GBG64524.1 - 0.061 13.6 0.4 0.14 12.5 0.4 1.6 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_5 PF13719.6 GBG64524.1 - 0.48 10.2 2.9 0.94 9.3 2.9 1.5 1 1 0 1 1 1 0 zinc-ribbon domain PEPCK_ATP PF01293.20 GBG64526.1 - 5.7e-213 707.7 0.0 6.9e-213 707.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 GBG64526.1 - 0.087 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 GBG64527.1 - 4.7e-213 708.0 0.0 5.5e-213 707.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 GBG64527.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain CLP_protease PF00574.23 GBG64528.1 - 2.1e-65 220.0 0.1 9.9e-56 188.5 0.0 2.3 2 0 0 2 2 2 2 Clp protease LAP1C PF05609.12 GBG64529.1 - 9 5.3 20.0 13 4.8 20.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Dynactin_p22 PF07426.11 GBG64530.1 - 0.024 14.5 1.1 0.024 14.5 1.1 1.8 1 1 0 1 1 1 0 Dynactin subunit p22 TolA_bind_tri PF16331.5 GBG64530.1 - 0.092 12.8 6.5 0.21 11.7 4.6 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation DDRGK PF09756.9 GBG64530.1 - 0.12 11.9 9.1 0.2 11.2 9.1 1.2 1 0 0 1 1 1 0 DDRGK domain DUF775 PF05603.12 GBG64530.1 - 3 7.3 4.4 0.55 9.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF775) ALMT PF11744.8 GBG64530.1 - 4.4 6.0 7.6 0.48 9.2 2.7 1.7 1 1 1 2 2 2 0 Aluminium activated malate transporter RT_RNaseH_2 PF17919.1 GBG64531.1 - 1.6e-31 108.3 0.0 3.3e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64531.1 - 7.1e-31 106.6 0.0 1.4e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64531.1 - 9.3e-20 70.5 0.5 2.1e-19 69.4 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64531.1 - 7.7e-18 64.8 0.0 2.4e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG64531.1 - 5e-05 22.9 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG64531.1 - 0.00047 20.3 0.1 0.0014 18.8 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger ANAPC8 PF04049.13 GBG64532.1 - 5.9e-21 75.0 0.1 5.9e-21 75.0 0.1 3.5 4 1 1 5 5 5 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 GBG64532.1 - 7.9e-21 73.0 37.0 2.7e-06 27.0 0.6 9.3 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 GBG64532.1 - 6.2e-18 63.5 28.8 0.0013 18.8 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 GBG64532.1 - 4.6e-15 54.4 48.0 0.0012 18.8 0.9 11.0 11 1 0 11 11 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 GBG64532.1 - 1.1e-14 53.8 9.9 2.8e-08 33.3 0.1 5.6 4 2 2 6 6 6 3 TPR repeat TPR_16 PF13432.6 GBG64532.1 - 1.2e-13 51.5 31.2 1.8e-07 31.7 0.4 7.9 6 3 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 GBG64532.1 - 4.9e-13 48.7 28.2 0.0004 21.0 0.1 9.4 5 3 5 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 GBG64532.1 - 2.1e-08 34.5 24.5 0.04 14.4 0.0 7.6 6 2 2 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG64532.1 - 5.7e-06 26.5 33.7 0.0074 16.5 0.0 6.6 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GBG64532.1 - 1.1e-05 25.5 17.4 0.0052 17.1 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG64532.1 - 0.00074 19.4 22.2 2.6 8.3 0.5 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 GBG64532.1 - 0.0008 18.7 18.5 0.0022 17.2 0.6 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.10 GBG64532.1 - 0.0019 17.3 0.0 0.1 11.5 0.0 2.7 2 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 GBG64532.1 - 0.01 16.1 37.5 0.056 13.7 0.2 8.1 5 3 1 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG64532.1 - 0.021 15.0 0.8 0.021 15.0 0.8 4.5 3 1 3 6 6 6 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GBG64532.1 - 0.022 14.2 0.1 2.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_6 PF13174.6 GBG64532.1 - 0.027 15.1 40.5 2.3 9.0 1.2 10.2 11 0 0 11 11 11 0 Tetratricopeptide repeat Nop53 PF07767.11 GBG64532.1 - 3.7 6.9 15.0 6.9 6.0 15.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cnd2 PF05786.14 GBG64532.1 - 5.6 5.5 15.3 8.5 4.9 15.3 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 Glyco_hydro_100 PF12899.7 GBG64533.1 - 1.4e-209 696.2 0.0 1.6e-209 696.0 0.0 1.0 1 0 0 1 1 1 1 Alkaline and neutral invertase GDE_C PF06202.14 GBG64533.1 - 0.00028 19.9 0.0 0.009 15.0 0.1 2.6 2 1 0 2 2 2 1 Amylo-alpha-1,6-glucosidase ABC2_membrane PF01061.24 GBG64535.1 - 4.8e-47 160.1 17.3 6.5e-47 159.7 17.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GBG64535.1 - 3.1e-24 86.1 0.0 5.6e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG64535.1 - 2.2e-05 24.5 0.6 0.54 10.0 0.1 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GBG64535.1 - 0.00021 20.9 0.0 0.00047 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG64535.1 - 0.00098 19.5 0.2 0.0039 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 GBG64535.1 - 0.0015 17.8 12.0 0.0025 17.0 12.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GBG64535.1 - 0.0038 17.1 0.1 0.0072 16.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_2 PF12679.7 GBG64535.1 - 0.023 14.0 0.4 0.023 14.0 0.4 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein MMR_HSR1 PF01926.23 GBG64535.1 - 0.038 14.1 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 GBG64535.1 - 0.047 13.1 0.2 1.8 7.9 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GBG64535.1 - 0.091 12.5 0.4 0.28 11.0 0.4 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3915 PF13054.6 GBG64535.1 - 0.095 12.7 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) AAA_22 PF13401.6 GBG64535.1 - 0.12 12.7 0.1 0.31 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GBG64535.1 - 0.17 12.1 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GBG64535.1 - 8.7 6.8 6.8 1.1 9.8 0.3 2.2 2 0 0 2 2 2 0 AAA domain PPR PF01535.20 GBG64536.1 - 1.1e-60 197.8 39.6 7.8e-07 28.9 0.1 15.4 15 0 0 15 15 15 13 PPR repeat PPR_2 PF13041.6 GBG64536.1 - 1.9e-58 194.4 14.5 1.4e-11 44.4 0.2 13.0 3 3 10 13 13 13 13 PPR repeat family PPR_3 PF13812.6 GBG64536.1 - 5e-41 138.6 0.0 7.3e-12 45.2 0.0 8.7 5 3 3 9 9 9 8 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG64536.1 - 2.1e-30 104.1 2.8 5.4e-08 32.4 0.0 10.8 13 0 0 13 13 13 4 PPR repeat PPR_long PF17177.4 GBG64536.1 - 8.9e-23 80.8 0.0 5.1e-06 26.0 0.0 4.3 2 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP Exog_C PF18026.1 GBG64536.1 - 7.9e-07 29.0 0.5 25 5.0 0.0 7.5 7 0 0 7 7 7 0 Endo/exonuclease (EXOG) C-terminal domain TPR_14 PF13428.6 GBG64536.1 - 0.00023 21.7 1.8 0.56 11.2 0.1 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat ATP13 PF12921.7 GBG64536.1 - 0.0021 17.9 0.0 2.8 7.8 0.0 4.6 4 0 0 4 4 4 1 Mitochondrial ATPase expression RPM2 PF08579.11 GBG64536.1 - 0.14 12.5 0.0 15 6.0 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.6 GBG64536.1 - 0.34 11.1 2.5 69 3.8 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG64537.1 - 0.00016 21.3 0.0 0.00038 20.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG64537.1 - 0.0011 19.3 2.2 0.021 15.1 0.0 3.7 4 0 0 4 4 4 1 Retrotransposon gag protein DUF3006 PF11213.8 GBG64537.1 - 0.0094 16.2 1.7 0.021 15.0 1.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) CLZ PF16526.5 GBG64537.1 - 2.1 8.8 11.9 1.2 9.6 0.6 3.8 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RT_RNaseH PF17917.1 GBG64538.1 - 2.4e-30 104.9 0.1 5e-30 103.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64538.1 - 1.9e-25 88.8 0.0 5.5e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64538.1 - 2e-10 40.6 0.0 3.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Cellulose_synt PF03552.14 GBG64539.1 - 0 1064.5 12.3 0 1062.5 12.3 1.7 1 1 0 1 1 1 1 Cellulose synthase Glyco_trans_2_3 PF13632.6 GBG64539.1 - 6.2e-08 32.8 1.7 6.2e-08 32.8 1.7 3.3 4 0 0 4 4 4 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG64539.1 - 8.3e-05 22.5 0.8 0.00027 20.8 0.1 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG64539.1 - 0.0051 16.7 1.0 0.2 11.5 0.0 3.1 3 0 0 3 3 3 1 Glycosyltransferase like family 2 DUF485 PF04341.12 GBG64539.1 - 7.3 6.6 7.0 16 5.5 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Ion_trans_2 PF07885.16 GBG64540.1 - 2.5e-14 53.0 19.5 1.4e-13 50.6 9.5 2.2 2 0 0 2 2 2 2 Ion channel EF-hand_1 PF00036.32 GBG64540.1 - 6e-05 22.3 1.0 0.18 11.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GBG64540.1 - 0.00053 19.7 0.4 0.4 10.7 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GBG64540.1 - 0.0017 17.8 0.3 0.078 12.5 0.0 2.5 2 0 0 2 2 2 1 EF hand Ion_trans PF00520.31 GBG64540.1 - 0.0072 15.6 0.0 0.0094 15.2 0.0 1.3 1 1 0 1 1 1 1 Ion transport protein EF-hand_7 PF13499.6 GBG64540.1 - 0.0084 16.5 5.4 0.3 11.6 0.0 2.5 2 1 0 3 3 3 2 EF-hand domain pair MFAP1 PF06991.11 GBG64540.1 - 0.056 13.3 5.9 0.64 9.8 0.1 2.1 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing Ost5 PF05251.12 GBG64540.1 - 0.34 11.2 5.8 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Myb_DNA-bind_4 PF13837.6 GBG64542.1 - 5e-06 26.8 1.3 7.8e-06 26.2 1.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG64542.1 - 0.0011 18.9 0.2 0.0017 18.4 0.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG64542.1 - 0.0091 16.2 0.0 0.019 15.1 0.0 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG64543.1 - 5.7e-33 112.9 0.0 1.3e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64543.1 - 5.7e-30 103.7 0.0 1.3e-29 102.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64543.1 - 4.1e-29 101.7 0.1 7.9e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64543.1 - 5.5e-14 52.0 0.0 1.4e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF3304 PF11745.8 GBG64543.1 - 0.83 10.1 12.3 2.2 8.7 12.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) CDC45 PF02724.14 GBG64543.1 - 1.8 6.7 17.8 2.4 6.3 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG64543.1 - 3 7.6 21.5 5.7 6.7 21.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Exonuc_VII_L PF02601.15 GBG64544.1 - 0.91 9.0 11.2 2 7.9 11.2 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit HC2 PF07382.11 GBG64546.1 - 0.59 10.2 14.9 0.78 9.8 14.9 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 ERM PF00769.19 GBG64547.1 - 0.00033 20.6 17.3 0.00044 20.2 17.3 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family zf-C4H2 PF10146.9 GBG64547.1 - 0.0068 16.7 6.7 0.011 16.1 6.7 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein RR_TM4-6 PF06459.12 GBG64547.1 - 0.0086 15.9 8.9 0.011 15.5 8.9 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 HrpF PF06266.12 GBG64547.1 - 0.051 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 HrpF protein DUF812 PF05667.11 GBG64547.1 - 0.086 11.7 12.2 0.11 11.3 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6_N PF17675.1 GBG64547.1 - 0.089 13.3 24.7 0.22 12.1 23.9 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 GBG64547.1 - 0.23 10.3 14.9 0.33 9.8 14.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Borrelia_P83 PF05262.11 GBG64547.1 - 0.28 9.6 9.8 0.37 9.2 9.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NACHT_N PF17100.5 GBG64547.1 - 0.33 10.8 7.2 0.54 10.1 7.2 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Prominin PF05478.11 GBG64547.1 - 0.34 8.8 2.6 0.46 8.4 2.6 1.2 1 0 0 1 1 1 0 Prominin Golgin_A5 PF09787.9 GBG64547.1 - 0.34 10.3 16.8 0.56 9.6 16.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 LMBR1 PF04791.16 GBG64547.1 - 0.44 9.4 1.8 0.52 9.2 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Med30 PF11315.8 GBG64547.1 - 1.3 9.2 13.1 1.8 8.7 9.9 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 V_ATPase_I PF01496.19 GBG64547.1 - 1.7 6.5 7.2 2.1 6.1 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 GBG64547.1 - 1.7 7.6 10.7 2.3 7.2 10.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1043 PF06295.12 GBG64547.1 - 1.9 8.5 6.4 16 5.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) YabA PF06156.13 GBG64547.1 - 1.9 9.2 13.9 3.4 8.4 8.4 2.8 2 1 1 3 3 3 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 GBG64547.1 - 2.6 7.5 8.7 4.3 6.8 8.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_11 PF13086.6 GBG64547.1 - 4.6 6.9 9.8 6.3 6.5 9.8 1.1 1 0 0 1 1 1 0 AAA domain ERM PF00769.19 GBG64548.1 - 0.00033 20.6 17.3 0.00044 20.2 17.3 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family zf-C4H2 PF10146.9 GBG64548.1 - 0.0068 16.7 6.7 0.011 16.1 6.7 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein RR_TM4-6 PF06459.12 GBG64548.1 - 0.0086 15.9 8.9 0.011 15.5 8.9 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 HrpF PF06266.12 GBG64548.1 - 0.051 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 HrpF protein DUF812 PF05667.11 GBG64548.1 - 0.086 11.7 12.2 0.11 11.3 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6_N PF17675.1 GBG64548.1 - 0.089 13.3 24.7 0.22 12.1 23.9 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 GBG64548.1 - 0.23 10.3 14.9 0.33 9.8 14.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Borrelia_P83 PF05262.11 GBG64548.1 - 0.28 9.6 9.8 0.37 9.2 9.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NACHT_N PF17100.5 GBG64548.1 - 0.33 10.8 7.2 0.54 10.1 7.2 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Prominin PF05478.11 GBG64548.1 - 0.34 8.8 2.6 0.46 8.4 2.6 1.2 1 0 0 1 1 1 0 Prominin Golgin_A5 PF09787.9 GBG64548.1 - 0.34 10.3 16.8 0.56 9.6 16.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 LMBR1 PF04791.16 GBG64548.1 - 0.44 9.4 1.8 0.52 9.2 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Med30 PF11315.8 GBG64548.1 - 1.3 9.2 13.1 1.8 8.7 9.9 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 V_ATPase_I PF01496.19 GBG64548.1 - 1.7 6.5 7.2 2.1 6.1 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 GBG64548.1 - 1.7 7.6 10.7 2.3 7.2 10.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1043 PF06295.12 GBG64548.1 - 1.9 8.5 6.4 16 5.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) YabA PF06156.13 GBG64548.1 - 1.9 9.2 13.9 3.4 8.4 8.4 2.8 2 1 1 3 3 3 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 GBG64548.1 - 2.6 7.5 8.7 4.3 6.8 8.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_11 PF13086.6 GBG64548.1 - 4.6 6.9 9.8 6.3 6.5 9.8 1.1 1 0 0 1 1 1 0 AAA domain SNase PF00565.17 GBG64549.1 - 5.3e-64 213.4 0.6 5.2e-14 52.6 0.0 6.3 6 0 0 6 6 6 6 Staphylococcal nuclease homologue TUDOR PF00567.24 GBG64549.1 - 3e-16 59.5 0.0 6.3e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 GBG64549.1 - 0.031 14.7 0.1 4.7 7.8 0.0 3.5 3 0 0 3 3 3 0 Agenet domain Crust_neuro_H PF03858.13 GBG64550.1 - 0.024 15.4 0.6 0.11 13.3 0.0 2.4 2 0 0 2 2 2 0 Crustacean neurohormone H CAP_N PF01213.19 GBG64550.1 - 0.66 9.4 15.1 0.62 9.5 2.6 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GBG64550.1 - 0.68 10.0 7.1 7.8 6.5 1.5 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator NeA_P2 PF12312.8 GBG64550.1 - 1.2 8.5 8.8 0.39 10.1 0.7 2.3 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Peptidase_M16_M PF16187.5 GBG64551.1 - 3.4e-76 256.2 0.0 9.4e-40 136.7 0.0 2.4 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GBG64551.1 - 1.4e-35 122.4 0.6 2.5e-34 118.4 0.1 2.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GBG64551.1 - 8.6e-27 94.3 0.0 1.9e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain CENP-B_dimeris PF09026.10 GBG64551.1 - 0.48 10.8 26.8 2.4 8.6 0.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BUD22 PF09073.10 GBG64551.1 - 0.76 9.1 17.4 1.3 8.2 15.8 1.9 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 GBG64551.1 - 2.4 7.5 17.7 4.8 6.5 17.7 1.4 1 0 0 1 1 1 0 SDA1 MADF_DNA_bdg PF10545.9 GBG64552.1 - 0.11 12.9 0.2 1.2 9.5 0.1 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pedibin PF08182.11 GBG64553.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Pedibin/Hym-346 family Pedibin PF08182.11 GBG64554.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Pedibin/Hym-346 family DUF659 PF04937.15 GBG64555.1 - 6.4e-36 123.5 0.1 9.1e-36 123.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) NOP19 PF10863.8 GBG64556.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Nucleolar protein 19 F-box_5 PF18511.1 GBG64557.1 - 1.2e-07 31.2 0.2 2.3e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 F-box LRR_4 PF12799.7 GBG64557.1 - 0.0017 18.7 3.9 3.2 8.3 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG64557.1 - 0.0017 18.2 8.0 26 5.2 0.0 6.5 6 0 0 6 6 6 1 Leucine Rich repeat PBP1_TM PF14812.6 GBG64557.1 - 0.7 10.3 2.5 0.46 10.9 0.2 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM104 PF15434.6 GBG64557.1 - 3.1 8.4 12.0 5.9 7.5 5.5 2.7 2 0 0 2 2 2 0 Family 104 SR-25 PF10500.9 GBG64557.1 - 8.4 5.9 20.7 5.2 6.6 12.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PIF1 PF05970.14 GBG64558.1 - 1e-82 278.2 0.0 3.9e-47 161.2 0.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 GBG64558.1 - 0.00023 21.0 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG64558.1 - 0.0038 17.6 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG64558.1 - 0.023 15.1 0.0 0.069 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Helitron_like_N PF14214.6 GBG64558.1 - 0.035 14.3 0.6 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus UPF0731 PF14982.6 GBG64558.1 - 6.1 7.1 6.1 31 4.8 0.2 2.9 1 1 1 2 2 2 0 UPF0731 family Sorting_nexin PF03700.13 GBG64559.1 - 0.074 13.6 0.3 0.12 13.0 0.3 1.2 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain RT_RNaseH_2 PF17919.1 GBG64560.1 - 2.9e-26 91.4 0.0 5.1e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64560.1 - 1.7e-24 86.1 0.0 3.8e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64560.1 - 5.8e-17 61.9 0.0 1.2e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG64560.1 - 9.2e-06 25.5 3.1 1.9e-05 24.5 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG64560.1 - 0.00059 20.4 0.0 0.0017 19.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64560.1 - 0.0024 18.4 0.0 0.006 17.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64560.1 - 0.0041 16.9 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64560.1 - 0.063 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG64560.1 - 0.58 10.0 7.1 0.084 12.7 3.0 1.8 2 0 0 2 2 2 0 Zinc knuckle Nop53 PF07767.11 GBG64560.1 - 7.8 5.8 13.9 14 4.9 13.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF538 PF04398.12 GBG64561.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF538 RAP1 PF07218.11 GBG64561.1 - 3.6 5.8 19.0 5 5.3 19.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4667 PF15700.5 GBG64561.1 - 5.2 7.1 24.5 12 5.9 21.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) RT_RNaseH_2 PF17919.1 GBG64562.1 - 1.1e-35 121.6 0.0 2.1e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64562.1 - 3e-32 111.0 0.0 6.6e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64562.1 - 3e-26 92.3 0.0 4.7e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG64562.1 - 2.1e-08 33.9 1.2 4.3e-08 32.9 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG64562.1 - 0.17 11.7 6.0 0.045 13.6 2.7 1.8 2 0 0 2 2 2 0 Zinc knuckle Presenilin PF01080.17 GBG64563.1 - 0.28 9.9 6.1 0.41 9.3 6.1 1.3 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 GBG64563.1 - 2.8 6.2 17.7 3.7 5.8 17.7 1.1 1 0 0 1 1 1 0 Menin RT_RNaseH PF17917.1 GBG64564.1 - 9.5e-28 96.6 0.1 2.1e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64564.1 - 9.1e-22 77.0 0.1 1.9e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG64564.1 - 0.0037 17.2 2.8 0.005 16.8 1.2 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 GBG64564.1 - 0.58 10.3 4.8 1.6 8.9 4.8 1.8 1 0 0 1 1 1 0 Zinc knuckle eIF-3c_N PF05470.12 GBG64565.1 - 0.00043 18.8 1.1 0.00043 18.8 1.1 1.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NPV_P10 PF05531.12 GBG64565.1 - 0.12 12.9 0.1 0.44 11.1 0.1 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RT_RNaseH_2 PF17919.1 GBG64568.1 - 6.4e-12 45.4 0.0 1.9e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64568.1 - 8.9e-05 22.1 0.0 0.00023 20.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64568.1 - 0.0015 18.8 0.0 0.0047 17.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG64568.1 - 0.0044 17.3 11.0 0.061 13.6 0.0 5.4 6 1 0 6 6 6 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG64568.1 - 0.67 10.5 3.1 9.5 6.8 1.9 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1465 PF07323.12 GBG64568.1 - 0.85 9.5 0.0 0.85 9.5 0.0 3.4 3 1 0 4 4 4 0 Protein of unknown function (DUF1465) Use1 PF09753.9 GBG64568.1 - 0.89 9.2 16.2 5.7 6.6 12.5 2.4 2 1 0 2 2 2 0 Membrane fusion protein Use1 AIF-MLS PF14962.6 GBG64568.1 - 2.9 7.8 7.5 5.7 6.9 7.5 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Syntaxin-6_N PF09177.11 GBG64568.1 - 6.9 7.3 8.6 6.2 7.4 0.1 3.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal HXXSHH PF07586.11 GBG64568.1 - 8 5.9 13.8 0.72 9.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1552) Myb_DNA-bind_4 PF13837.6 GBG64569.1 - 1e-05 25.8 2.4 1e-05 25.8 2.4 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Orf78 PF06024.12 GBG64569.1 - 0.0012 19.1 3.1 0.11 12.8 0.1 2.5 2 0 0 2 2 2 1 Orf78 (ac78) FAM176 PF14851.6 GBG64569.1 - 0.0019 17.8 4.6 0.0019 17.8 4.6 3.6 2 1 2 4 4 3 1 FAM176 family DUF1676 PF07898.13 GBG64569.1 - 0.0066 16.5 0.0 5.8 6.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1676) V_ATPase_I PF01496.19 GBG64569.1 - 0.014 13.3 0.2 0.027 12.4 0.1 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Sigma70_ner PF04546.13 GBG64569.1 - 0.03 14.2 23.7 0.41 10.5 5.9 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.12 GBG64569.1 - 0.063 11.5 29.8 0.14 10.3 10.4 2.3 2 0 0 2 2 2 0 Nop14-like family Afi1 PF07792.12 GBG64569.1 - 0.12 12.9 22.3 0.12 12.8 4.4 3.0 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.22 GBG64569.1 - 0.12 11.6 0.1 0.3 10.2 0.1 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter Myb_DNA-binding PF00249.31 GBG64569.1 - 0.12 12.6 3.4 0.28 11.4 3.4 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain DUF4834 PF16118.5 GBG64569.1 - 0.14 13.1 0.3 22 6.1 0.0 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 GBG64569.1 - 0.17 11.8 2.9 1.1 9.1 0.0 2.7 2 1 0 2 2 2 0 TMEM9 SID-1_RNA_chan PF13965.6 GBG64569.1 - 0.26 9.6 0.1 0.46 8.8 0.0 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2615 PF11027.8 GBG64569.1 - 2.3 8.4 10.5 1.1 9.5 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2615) RVT_1 PF00078.27 GBG64571.1 - 7.6e-34 117.2 0.2 1.4e-33 116.2 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64571.1 - 3.8e-30 103.9 0.0 1.3e-29 102.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64571.1 - 4e-30 104.2 0.0 1.1e-29 102.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64571.1 - 2.8e-19 68.9 1.1 6e-19 67.9 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG64571.1 - 0.00023 21.3 0.1 0.00096 19.3 0.1 2.2 2 0 0 2 2 2 1 H2C2 zinc finger rve PF00665.26 GBG64571.1 - 0.00025 21.2 0.0 0.00061 20.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Phage_GPO PF05929.11 GBG64571.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Retrotrans_gag PF03732.17 GBG64572.1 - 0.012 15.8 1.9 0.29 11.4 0.0 3.3 2 1 1 3 3 3 0 Retrotransposon gag protein DUF2927 PF11150.8 GBG64572.1 - 0.3 11.1 4.6 4.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2927) Vps54 PF07928.12 GBG64574.1 - 5e-30 104.7 1.4 1.5e-20 74.0 0.2 2.2 1 1 1 2 2 2 2 Vps54-like protein PsaN PF05479.11 GBG64575.1 - 9.8e-31 106.7 5.0 9.8e-31 106.7 5.0 1.3 1 1 0 1 1 1 1 Photosystem I reaction centre subunit N (PSAN or PSI-N) PsbQ PF05757.11 GBG64575.1 - 0.019 14.7 0.9 0.026 14.3 0.9 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) PsaN PF05479.11 GBG64576.1 - 4.9e-46 156.2 5.3 4.9e-46 156.2 5.3 1.2 1 1 0 1 1 1 1 Photosystem I reaction centre subunit N (PSAN or PSI-N) PsbQ PF05757.11 GBG64576.1 - 0.027 14.2 0.9 0.038 13.7 0.9 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF659 PF04937.15 GBG64577.1 - 1.2e-37 129.1 0.1 2.3e-37 128.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Sirohm_synth_C PF14823.6 GBG64577.1 - 0.22 11.2 1.9 0.57 9.9 1.1 2.1 2 1 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Presenilin PF01080.17 GBG64578.1 - 9.3 4.9 9.3 8.9 5.0 9.3 1.1 1 0 0 1 1 1 0 Presenilin FAD_binding_2 PF00890.24 GBG64579.1 - 2.6e-31 109.1 0.0 3.5e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GBG64579.1 - 4.5e-24 85.2 0.1 1e-23 84.1 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GBG64579.1 - 1.2e-19 70.5 0.0 2.3e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GBG64579.1 - 0.00059 20.0 0.0 0.03 14.5 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Aldolase PF01081.19 GBG64579.1 - 0.0029 17.1 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 KDPG and KHG aldolase DAO PF01266.24 GBG64579.1 - 0.025 14.1 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase mTERF PF02536.14 GBG64580.1 - 3.5e-51 174.0 9.4 1.4e-26 93.2 0.4 2.1 1 1 1 2 2 2 2 mTERF gag-asp_proteas PF13975.6 GBG64581.1 - 2.7e-07 31.1 0.2 1.5e-06 28.7 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG64581.1 - 2.6e-06 27.1 0.0 4.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Jnk-SapK_ap_N PF09744.9 GBG64581.1 - 0.00015 22.0 3.5 0.00015 22.0 3.5 3.1 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 Asp_protease_2 PF13650.6 GBG64581.1 - 0.00082 20.0 0.0 0.003 18.2 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64581.1 - 0.0047 16.7 0.6 0.0099 15.7 0.6 1.5 1 0 0 1 1 1 1 Aspartyl protease YqzH PF14164.6 GBG64581.1 - 0.13 12.3 0.1 0.41 10.8 0.1 1.8 1 0 0 1 1 1 0 YqzH-like protein zf-HC2 PF13490.6 GBG64581.1 - 9 6.6 7.6 25 5.2 0.9 4.0 3 0 0 3 3 3 0 Putative zinc-finger gag-asp_proteas PF13975.6 GBG64582.1 - 1.2e-07 32.2 0.3 7.8e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG64582.1 - 1.2e-06 28.2 0.0 2.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG64582.1 - 0.00043 20.9 0.0 0.0016 19.1 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64582.1 - 0.0023 17.7 0.6 0.0052 16.6 0.6 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG64582.1 - 0.085 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4604 PF15377.6 GBG64582.1 - 0.62 10.5 17.5 1.4 9.3 17.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CENP-N PF05238.13 GBG64582.1 - 6.3 6.0 6.7 8.7 5.5 5.4 1.8 2 0 0 2 2 2 0 Kinetochore protein CHL4 like Presenilin PF01080.17 GBG64582.1 - 6.6 5.4 4.6 9.8 4.8 4.6 1.3 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.6 GBG64582.1 - 8.9 6.2 11.5 18 5.2 11.5 1.4 1 0 0 1 1 1 0 Spore coat protein CotO RPAP1_N PF08621.10 GBG64583.1 - 1.1e-14 53.9 1.1 1.1e-14 53.9 1.1 2.2 2 0 0 2 2 2 1 RPAP1-like, N-terminal RPAP1_C PF08620.10 GBG64583.1 - 4.1e-14 52.4 0.1 6.1e-13 48.7 0.1 2.4 1 1 0 1 1 1 1 RPAP1-like, C-terminal Asp_protease_2 PF13650.6 GBG64586.1 - 0.0023 18.6 0.0 0.0055 17.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64586.1 - 0.0085 16.6 0.0 0.025 15.1 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64586.1 - 0.0094 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG64586.1 - 0.0098 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) LMBR1 PF04791.16 GBG64586.1 - 0.083 11.8 1.9 0.11 11.4 1.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 GBG64586.1 - 1 7.2 5.1 1.5 6.7 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3323 PF11796.8 GBG64586.1 - 3.1 7.6 10.0 5.8 6.8 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Ebp2 PF05890.12 GBG64586.1 - 7.8 6.0 23.3 16 4.9 22.0 2.0 2 0 0 2 2 2 0 Eukaryotic rRNA processing protein EBP2 RVT_1 PF00078.27 GBG64587.1 - 6.1e-17 61.9 0.1 1.4e-16 60.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG64587.1 - 2.2e-11 44.0 0.0 5.8e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG64587.1 - 1.3e-09 37.8 0.0 3.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1126 PF06565.12 GBG64587.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 DUF1126 PH-like domain RT_RNaseH_2 PF17919.1 GBG64588.1 - 2.3e-27 95.0 0.0 4.6e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64588.1 - 1.4e-24 86.3 0.0 3e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64588.1 - 2.6e-19 69.1 0.5 9.2e-19 67.3 0.4 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG64588.1 - 1.6e-08 34.7 0.0 5.3e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG64588.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF4574 PF15141.6 GBG64589.1 - 1.6 8.7 3.9 8.4 6.4 2.5 2.7 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 TAXi_N PF14543.6 GBG64590.1 - 1.9e-31 109.6 4.0 1.1e-30 107.2 4.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GBG64590.1 - 6.7e-19 68.4 0.0 1.6e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 GBG64590.1 - 2e-14 53.7 0.0 2.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal MAT1 PF06391.13 GBG64591.1 - 3.5e-28 98.8 6.7 5.9e-28 98.1 6.7 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 K_oxygenase PF13434.6 GBG64591.1 - 0.055 12.6 0.0 0.064 12.4 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) RVT_1 PF00078.27 GBG64592.1 - 2.8e-23 82.6 0.0 4.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64592.1 - 5.7e-21 74.4 0.0 1.3e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64592.1 - 7.4e-20 71.2 0.0 1.5e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64593.1 - 1e-22 80.4 0.0 3.8e-22 78.6 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64593.1 - 6.7e-22 77.4 0.0 2.9e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64593.1 - 4.4e-11 42.7 0.2 9.4e-06 25.3 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG64593.1 - 1.1e-06 28.8 0.0 3.2e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG64593.1 - 0.011 15.5 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease PriC PF07445.12 GBG64593.1 - 0.024 14.6 8.4 0.032 14.2 5.1 2.5 2 0 0 2 2 2 0 Primosomal replication protein priC DUF4407 PF14362.6 GBG64593.1 - 0.89 8.8 10.2 1.6 8.0 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2497 PF10691.9 GBG64593.1 - 2.9 8.4 4.7 0.77 10.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Helo_like_N PF17111.5 GBG64593.1 - 9.1 5.6 9.5 1.5 8.1 0.1 2.9 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins Cys_Met_Meta_PP PF01053.20 GBG64594.1 - 1.7e-138 461.3 0.0 2.1e-138 461.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GBG64594.1 - 0.00022 20.3 0.0 0.00037 19.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 GBG64594.1 - 0.002 17.0 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein K_channel_TID PF07941.11 GBG64594.1 - 0.068 13.6 5.7 0.19 12.2 5.7 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Aminotran_1_2 PF00155.21 GBG64594.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II VasL PF12486.8 GBG64595.1 - 0.011 15.7 0.5 0.019 14.8 0.5 1.4 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL PPR_2 PF13041.6 GBG64596.1 - 8.5e-11 41.9 0.0 0.0016 18.6 0.0 3.6 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 GBG64596.1 - 1.8e-08 34.3 0.0 0.0078 16.3 0.0 2.4 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 GBG64596.1 - 1.1e-07 31.7 0.1 0.42 11.0 0.0 4.1 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 GBG64596.1 - 4e-07 29.6 0.0 0.032 13.6 0.0 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GBG64596.1 - 0.0022 17.6 0.0 7 6.4 0.0 3.6 4 0 0 4 4 4 1 PPR repeat Plant_zn_clust PF10533.9 GBG64596.1 - 0.01 15.8 0.7 0.037 14.0 0.7 2.0 1 0 0 1 1 1 0 Plant zinc cluster domain DEAD PF00270.29 GBG64597.1 - 8.4e-47 159.2 0.0 2.1e-46 157.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG64597.1 - 4.9e-28 97.7 0.0 1.2e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.12 GBG64597.1 - 2.8e-23 82.0 0.0 7e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 GBG64597.1 - 0.00024 21.1 0.0 0.00053 20.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG64597.1 - 0.076 12.4 0.0 0.076 12.4 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF4390 PF14334.6 GBG64597.1 - 0.11 11.9 0.0 0.46 9.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) DEAD PF00270.29 GBG64598.1 - 1.3e-46 158.6 0.0 3.3e-46 157.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG64598.1 - 1e-27 96.7 0.1 2.4e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.12 GBG64598.1 - 1.8e-23 82.7 0.0 4.1e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 GBG64598.1 - 0.00038 20.5 0.0 0.00084 19.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG64598.1 - 0.095 12.0 0.0 0.095 12.0 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF4390 PF14334.6 GBG64598.1 - 0.1 12.0 0.0 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) PPR_2 PF13041.6 GBG64599.1 - 2.6e-09 37.1 0.0 0.0016 18.6 0.0 3.6 2 2 3 5 5 5 2 PPR repeat family PPR PF01535.20 GBG64599.1 - 4.6e-07 29.7 0.2 0.42 11.0 0.0 4.1 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 GBG64599.1 - 5.2e-07 29.7 0.0 0.0078 16.3 0.0 2.4 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG64599.1 - 2.7e-06 26.9 0.0 0.032 13.6 0.0 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP Plant_zn_clust PF10533.9 GBG64599.1 - 0.0099 15.9 0.7 0.037 14.0 0.7 2.0 1 0 0 1 1 1 1 Plant zinc cluster domain PPR_1 PF12854.7 GBG64599.1 - 0.015 15.0 0.0 7 6.4 0.0 3.2 4 0 0 4 4 4 0 PPR repeat Integrase_H2C2 PF17921.1 GBG64602.1 - 9.9e-12 44.8 1.2 2.2e-11 43.7 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain HMG_box PF00505.19 GBG64603.1 - 2.4e-21 75.9 1.3 3.3e-21 75.5 1.3 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GBG64603.1 - 2.6e-12 47.1 0.8 4.1e-12 46.5 0.5 1.5 1 1 0 1 1 1 1 HMG-box domain HSA PF07529.13 GBG64605.1 - 0.26 11.7 2.7 0.54 10.6 2.7 1.4 1 0 0 1 1 1 0 HSA Laminin_G_3 PF13385.6 GBG64606.1 - 5.6e-131 432.4 38.4 1.1e-15 58.1 0.2 17.1 16 1 0 16 16 16 13 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 GBG64606.1 - 2e-32 112.4 8.2 0.00017 22.1 0.1 11.2 11 0 0 11 11 11 7 Laminin G domain REJ PF02010.15 GBG64606.1 - 1.1e-24 87.1 1.3 1.1e-24 87.1 1.3 1.7 2 0 0 2 2 2 1 REJ domain Big_9 PF17963.1 GBG64606.1 - 1.7e-13 51.1 39.2 0.006 17.3 0.0 14.3 14 0 0 14 14 14 3 Bacterial Ig domain Cadherin_5 PF17892.1 GBG64606.1 - 6.6e-08 32.4 7.1 0.00094 19.1 0.1 8.1 8 0 0 8 8 8 1 Cadherin-like domain Laminin_G_1 PF00054.23 GBG64606.1 - 7.9e-08 32.6 3.0 6.3 7.0 0.1 7.1 9 0 0 9 9 9 3 Laminin G domain Pentaxin PF00354.17 GBG64606.1 - 9.1e-08 32.0 9.8 0.019 14.6 0.0 7.2 8 0 0 8 8 8 2 Pentaxin family DUF1191 PF06697.12 GBG64606.1 - 4.5e-07 29.8 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Cadherin_4 PF17803.1 GBG64606.1 - 8.1e-06 26.4 26.6 0.087 13.5 0.3 9.0 8 0 0 8 8 7 3 Bacterial cadherin-like domain Cadherin_3 PF16184.5 GBG64606.1 - 0.0047 16.9 4.3 17 5.5 0.1 7.0 9 0 0 9 9 9 0 Cadherin-like GPS PF01825.21 GBG64606.1 - 0.066 13.7 0.1 0.21 12.2 0.1 1.9 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif EPV_E5 PF08135.11 GBG64606.1 - 2 8.8 8.2 5.2 7.5 8.2 1.6 1 0 0 1 1 1 0 Major transforming protein E5 family Laminin_G_3 PF13385.6 GBG64607.1 - 5.3e-131 432.5 38.2 1.1e-15 58.1 0.2 17.1 16 1 0 16 16 16 13 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 GBG64607.1 - 1.5e-32 112.8 8.4 0.00017 22.2 0.1 11.2 11 0 0 11 11 11 7 Laminin G domain REJ PF02010.15 GBG64607.1 - 1e-24 87.1 1.3 1e-24 87.1 1.3 1.7 2 0 0 2 2 2 1 REJ domain Big_9 PF17963.1 GBG64607.1 - 2.4e-13 50.6 35.2 0.0057 17.4 0.0 12.9 12 0 0 12 12 12 3 Bacterial Ig domain Laminin_G_1 PF00054.23 GBG64607.1 - 4.1e-08 33.5 2.5 6 7.1 0.1 7.1 9 0 0 9 9 9 3 Laminin G domain Pentaxin PF00354.17 GBG64607.1 - 7.3e-08 32.3 9.9 0.019 14.7 0.0 7.3 8 0 0 8 8 8 3 Pentaxin family DUF1191 PF06697.12 GBG64607.1 - 4.3e-07 29.9 0.0 9.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Cadherin_5 PF17892.1 GBG64607.1 - 4.7e-07 29.7 5.7 0.0009 19.2 0.1 7.2 7 0 0 7 7 7 1 Cadherin-like domain Cadherin_4 PF17803.1 GBG64607.1 - 7e-06 26.6 26.6 0.083 13.5 0.3 8.8 8 0 0 8 8 7 3 Bacterial cadherin-like domain Cadherin_3 PF16184.5 GBG64607.1 - 0.0028 17.6 3.9 16 5.6 0.1 7.0 9 0 0 9 9 9 0 Cadherin-like GPS PF01825.21 GBG64607.1 - 0.063 13.8 0.1 0.2 12.2 0.1 1.9 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif EPV_E5 PF08135.11 GBG64607.1 - 1.9 8.9 8.2 5 7.6 8.2 1.7 1 0 0 1 1 1 0 Major transforming protein E5 family zf-CCHC_3 PF13917.6 GBG64608.1 - 0.016 15.1 0.2 0.034 14.1 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle VGCC_beta4Aa_N PF12052.8 GBG64608.1 - 0.27 11.4 2.9 0.42 10.7 1.0 2.3 1 1 1 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal RT_RNaseH_2 PF17919.1 GBG64609.1 - 4.7e-32 110.0 0.0 9.7e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64609.1 - 8.8e-29 99.9 0.1 1.7e-28 99.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64609.1 - 5.3e-12 46.0 0.0 1.4e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG64609.1 - 0.0086 15.8 0.1 0.032 13.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) HAUS6_N PF14661.6 GBG64609.1 - 0.026 14.1 0.4 0.059 12.9 0.4 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Tmemb_cc2 PF10267.9 GBG64609.1 - 0.16 11.1 3.1 0.32 10.1 3.1 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Peptidase_S64 PF08192.11 GBG64609.1 - 0.36 9.3 2.0 0.58 8.6 2.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF737 PF05300.11 GBG64609.1 - 1.8 8.9 7.3 10 6.4 5.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Macoilin PF09726.9 GBG64609.1 - 1.8 7.0 8.0 2.9 6.4 8.0 1.2 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 GBG64609.1 - 3.2 5.9 5.7 4.4 5.5 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RVT_1 PF00078.27 GBG64610.1 - 7.4e-33 113.9 0.0 1.1e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64610.1 - 4.6e-09 36.1 0.0 9.3e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64610.1 - 0.00035 21.1 0.0 0.00072 20.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64610.1 - 0.00083 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG64610.1 - 0.0085 16.7 0.0 0.019 15.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Sporozoite_P67 PF05642.11 GBG64610.1 - 0.25 9.4 10.5 0.17 9.9 0.8 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen YabA PF06156.13 GBG64610.1 - 0.45 11.2 2.7 0.91 10.2 0.0 2.6 3 0 0 3 3 3 0 Initiation control protein YabA GCN5L1 PF06320.13 GBG64610.1 - 1.8 8.7 6.7 1 9.5 4.3 1.8 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) FSA_C PF10479.9 GBG64610.1 - 6.5 4.8 9.7 0.049 11.8 0.8 1.7 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus RVT_1 PF00078.27 GBG64611.1 - 5.6e-33 114.3 0.0 8.7e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64611.1 - 3.4e-09 36.6 0.0 7.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64611.1 - 0.00027 21.4 0.0 0.00056 20.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64611.1 - 0.00058 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG64611.1 - 0.0065 17.1 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease EGF_Tenascin PF18720.1 GBG64611.1 - 0.023 14.7 5.8 0.045 13.8 5.8 1.5 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 GBG64611.1 - 0.035 14.5 10.1 0.068 13.6 10.1 1.5 1 0 0 1 1 1 0 EGF-like domain Sporozoite_P67 PF05642.11 GBG64611.1 - 0.069 11.2 9.3 0.092 10.8 0.4 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen YabA PF06156.13 GBG64611.1 - 0.72 10.5 0.0 0.72 10.5 0.0 3.1 4 0 0 4 4 3 0 Initiation control protein YabA hEGF PF12661.7 GBG64611.1 - 1.1 10.1 10.4 2.2 9.0 10.4 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF DUF1676 PF07898.13 GBG64611.1 - 1.1 9.3 4.3 0.72 9.9 1.4 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF1676) GCN5L1 PF06320.13 GBG64611.1 - 1.3 9.2 6.7 0.81 9.9 4.3 1.9 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) FSA_C PF10479.9 GBG64611.1 - 3.4 5.7 9.3 0.038 12.1 0.8 1.8 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus EGF PF00008.27 GBG64611.1 - 5.2 7.5 10.0 10 6.6 10.0 1.5 1 0 0 1 1 1 0 EGF-like domain DUF4208 PF13907.6 GBG64612.1 - 0.0078 16.6 0.3 0.15 12.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Pox_VLTF3 PF04947.14 GBG64612.1 - 0.13 11.9 0.4 7.2 6.3 0.1 2.2 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like RT_RNaseH_2 PF17919.1 GBG64613.1 - 2.6e-28 98.0 0.0 4.3e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64613.1 - 1.5e-25 89.5 0.0 2.4e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64613.1 - 1.1e-11 44.7 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GCP5-Mod21 PF14609.6 GBG64613.1 - 2.7 6.2 3.6 4.2 5.6 3.6 1.2 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Integrase_H2C2 PF17921.1 GBG64614.1 - 1.8e-19 69.6 0.1 6.3e-19 67.8 0.1 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64614.1 - 4.9e-10 39.6 0.2 3.1e-09 37.0 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG64614.1 - 0.033 14.4 0.1 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 H2C2 zinc finger NOA36 PF06524.12 GBG64614.1 - 0.68 9.2 33.5 0.99 8.7 20.5 2.3 2 0 0 2 2 2 0 NOA36 protein RVT_1 PF00078.27 GBG64615.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NPR3 PF03666.13 GBG64615.1 - 0.71 8.6 7.4 0.38 9.5 5.6 1.3 1 1 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 GBG64615.1 - 1.8 6.7 27.5 2.2 6.4 27.5 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG64615.1 - 1.8 7.0 27.7 3.3 6.2 27.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 GBG64615.1 - 2.1 7.6 27.8 3.3 7.0 27.8 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG64615.1 - 2.6 7.4 27.0 3.3 7.0 27.0 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG64615.1 - 4.4 6.8 16.4 6.4 6.2 16.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SURF2 PF05477.11 GBG64615.1 - 5.4 6.6 12.4 9 5.9 12.4 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RVT_1 PF00078.27 GBG64616.1 - 2.3e-09 37.1 0.1 3.9e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NPR3 PF03666.13 GBG64616.1 - 0.77 8.5 7.4 0.43 9.3 5.8 1.3 1 1 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 GBG64616.1 - 1.9 6.6 27.5 2.3 6.3 27.5 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG64616.1 - 2 6.9 27.7 3.5 6.1 27.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 GBG64616.1 - 2.2 7.5 27.8 3.5 6.9 27.8 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG64616.1 - 2.4 7.5 26.8 3.1 7.1 26.8 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG64616.1 - 5.4 6.5 16.7 8 5.9 16.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SURF2 PF05477.11 GBG64616.1 - 5.7 6.6 12.4 9.5 5.8 12.4 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) gag-asp_proteas PF13975.6 GBG64617.1 - 2.8e-05 24.6 0.0 9.9e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64617.1 - 0.024 15.3 0.0 0.069 13.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG64617.1 - 0.025 14.9 0.0 0.063 13.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64617.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG64617.1 - 0.35 10.8 1.4 0.59 10.0 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 GBG64618.1 - 1.7e-09 37.9 0.0 3.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG64618.1 - 1.3e-08 35.0 0.0 2.9e-07 30.7 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64618.1 - 1.5e-06 28.2 0.1 4e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG64618.1 - 0.051 13.9 0.0 0.17 12.2 0.0 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein PRD PF00874.20 GBG64619.1 - 0.084 13.2 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 PRD domain DUF1449 PF07290.11 GBG64620.1 - 0.0034 17.0 0.0 0.0047 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1449) DUF4637 PF15470.6 GBG64620.1 - 0.02 14.6 0.9 0.028 14.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) BUD22 PF09073.10 GBG64620.1 - 0.03 13.7 2.8 0.035 13.5 2.8 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 GBG64620.1 - 0.04 13.2 15.6 0.055 12.8 15.6 1.1 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 GBG64620.1 - 0.072 11.6 3.1 0.085 11.4 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 GBG64620.1 - 0.094 12.3 9.1 0.12 11.9 9.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.13 GBG64620.1 - 0.17 11.8 7.1 0.23 11.3 7.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.9 GBG64620.1 - 0.35 10.0 18.2 0.5 9.5 18.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 GBG64620.1 - 0.5 8.5 11.8 0.59 8.3 11.8 1.0 1 0 0 1 1 1 0 Nop14-like family TFB6 PF17110.5 GBG64620.1 - 0.89 9.3 4.4 1.4 8.6 4.4 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 GBG64620.1 - 1.3 8.6 7.2 0.49 10.1 4.4 1.7 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 GBG64620.1 - 1.5 6.9 19.2 1.8 6.5 19.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 GBG64620.1 - 3.7 7.5 8.7 5.9 6.9 8.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 GBG64620.1 - 7.7 5.8 15.4 11 5.3 15.4 1.1 1 0 0 1 1 1 0 SDA1 Myc_N PF01056.18 GBG64620.1 - 8.5 6.2 6.7 11 5.8 6.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region MREG PF15812.5 GBG64621.1 - 0.033 14.5 1.6 0.062 13.6 1.6 1.4 1 0 0 1 1 1 0 Melanoregulin F-box-like PF12937.7 GBG64622.1 - 3e-10 39.8 0.1 7.9e-10 38.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG64622.1 - 4e-07 29.7 0.2 1e-06 28.4 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GBG64622.1 - 0.00019 21.3 0.2 0.00046 20.1 0.2 1.6 1 0 0 1 1 1 1 F-box zf-C3HC PF07967.13 GBG64622.1 - 0.015 15.4 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 C3HC zinc finger-like TetR_C_11 PF16859.5 GBG64622.1 - 6.7 7.1 7.9 35 4.7 0.4 3.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Mpp10 PF04006.12 GBG64623.1 - 0.00067 18.2 31.6 0.00067 18.2 31.6 1.6 2 0 0 2 2 2 1 Mpp10 protein Nop14 PF04147.12 GBG64623.1 - 0.0013 17.1 34.3 0.0013 17.1 34.3 1.4 2 0 0 2 2 2 1 Nop14-like family CDC45 PF02724.14 GBG64623.1 - 0.0035 15.7 30.0 0.0046 15.3 30.0 1.3 1 0 0 1 1 1 1 CDC45-like protein V_ATPase_I PF01496.19 GBG64623.1 - 0.0055 14.7 4.5 0.0055 14.7 4.5 2.1 1 1 1 2 2 1 1 V-type ATPase 116kDa subunit family SGT1 PF07093.11 GBG64623.1 - 0.031 12.7 15.6 0.037 12.5 15.6 1.1 1 0 0 1 1 1 0 SGT1 protein RRN3 PF05327.11 GBG64623.1 - 0.078 11.5 17.4 0.098 11.2 17.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4589 PF15252.6 GBG64623.1 - 0.2 11.6 15.4 0.34 10.9 15.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Apt1 PF10351.9 GBG64623.1 - 0.24 10.2 18.6 0.31 9.8 18.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AJAP1_PANP_C PF15298.6 GBG64623.1 - 0.32 11.2 12.7 0.55 10.4 12.7 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus GPCR_chapero_1 PF11904.8 GBG64623.1 - 0.42 10.0 13.2 0.5 9.7 13.2 1.3 1 0 0 1 1 1 0 GPCR-chaperone DUF3439 PF11921.8 GBG64623.1 - 0.48 10.4 12.6 0.85 9.6 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PI3K_1B_p101 PF10486.9 GBG64623.1 - 0.63 7.7 10.2 0.85 7.3 10.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SRP-alpha_N PF04086.13 GBG64623.1 - 0.67 9.8 32.8 1.1 9.2 32.8 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 GBG64623.1 - 0.7 8.6 18.4 1 8.1 18.4 1.4 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 GBG64623.1 - 1.9 7.4 20.0 2.7 6.9 20.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 CCSAP PF15748.5 GBG64623.1 - 2.2 8.4 27.2 4.4 7.4 27.2 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TEX19 PF15553.6 GBG64623.1 - 9.1 6.2 8.8 15 5.5 8.8 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 zf-RING_2 PF13639.6 GBG64624.1 - 9.7e-09 35.4 7.3 2.6e-08 34.1 7.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG64624.1 - 6.7e-06 25.9 5.4 1.3e-05 24.9 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG64624.1 - 2e-05 24.5 5.8 0.00023 21.1 2.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GBG64624.1 - 2.4e-05 24.5 7.6 6.9e-05 23.1 7.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GBG64624.1 - 3.6e-05 23.5 7.0 8.8e-05 22.3 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GBG64624.1 - 8e-05 22.6 3.1 8e-05 22.6 3.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GBG64624.1 - 0.00051 19.8 5.0 0.001 18.8 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG64624.1 - 0.00063 19.6 5.2 0.0014 18.5 5.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 GBG64624.1 - 0.0027 17.4 3.8 0.0042 16.8 2.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger Zf_RING PF16744.5 GBG64624.1 - 0.0057 16.7 5.4 0.025 14.7 1.1 3.2 2 1 1 3 3 2 1 KIAA1045 RING finger RINGv PF12906.7 GBG64624.1 - 0.014 15.5 4.8 0.03 14.4 4.8 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 GBG64624.1 - 0.016 15.4 4.4 0.039 14.1 4.4 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 GBG64624.1 - 0.036 13.9 8.6 0.15 11.9 8.6 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 GBG64624.1 - 0.093 12.4 6.1 0.22 11.2 6.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type KIP1 PF07765.12 GBG64624.1 - 0.26 11.4 7.7 0.48 10.6 0.8 2.5 2 0 0 2 2 2 0 KIP1-like protein Baculo_IE-1 PF05290.11 GBG64624.1 - 0.45 10.5 5.8 1.1 9.1 5.8 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 GBG64624.1 - 1.3 9.2 3.5 12 6.1 3.5 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger Prok-RING_1 PF14446.6 GBG64624.1 - 6.3 6.8 6.4 3.9 7.5 1.5 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 GBG64624.1 - 8.2 6.3 7.0 18 5.2 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_2 PF07719.17 GBG64625.1 - 3.4e-11 42.4 2.2 8.6e-05 22.4 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG64625.1 - 2e-09 37.5 2.5 0.047 14.5 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG64625.1 - 2.5e-09 36.6 0.3 0.028 14.1 0.0 4.4 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.28 GBG64625.1 - 1.3e-08 34.3 0.9 1.1e-05 25.0 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG64625.1 - 6.8e-06 26.6 4.5 0.092 13.4 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 GBG64625.1 - 1.5e-05 25.0 3.5 0.53 10.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG64625.1 - 0.0015 18.5 0.1 0.093 13.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GBG64625.1 - 0.0019 18.3 0.7 1 9.5 0.2 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG64625.1 - 0.0097 16.4 4.7 1.2 9.7 0.2 3.7 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG64625.1 - 0.014 15.4 0.3 0.39 10.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG64625.1 - 0.054 13.8 1.9 0.56 10.5 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG64625.1 - 0.092 12.6 0.7 0.6 10.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M24_C PF16188.5 GBG64625.1 - 0.14 12.2 0.0 0.49 10.5 0.0 1.9 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 PC_rep PF01851.22 GBG64625.1 - 0.59 10.7 1.9 16 6.2 0.0 2.9 3 0 0 3 3 2 0 Proteasome/cyclosome repeat zf-CCHC PF00098.23 GBG64626.1 - 7.1e-05 22.7 1.9 0.00012 22.0 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle SOBP PF15279.6 GBG64626.1 - 0.39 11.3 5.0 0.55 10.8 5.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SAPS PF04499.15 GBG64626.1 - 0.86 8.3 7.7 0.94 8.2 7.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 GBG64626.1 - 2.8 5.7 9.3 3.7 5.3 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LPP20 PF02169.16 GBG64626.1 - 3.4 8.1 6.3 6.7 7.1 6.0 1.7 1 1 0 1 1 1 0 LPP20 lipoprotein Spore_III_AF PF09581.10 GBG64626.1 - 5.3 7.0 16.1 8.1 6.4 16.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF2362 PF10154.9 GBG64626.1 - 8.4 5.2 12.5 12 4.8 12.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) PRA-CH PF01502.18 GBG64627.1 - 6.7e-25 86.7 0.1 2e-24 85.2 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 GBG64627.1 - 1.2e-09 38.5 0.1 1.2e-09 38.5 0.1 3.5 3 1 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase Retrotrans_gag PF03732.17 GBG64627.1 - 0.0032 17.7 1.8 0.011 16.0 0.1 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein Ribosomal_60s PF00428.19 GBG64627.1 - 0.023 15.3 1.0 0.023 15.3 1.0 7.1 7 1 0 7 7 7 0 60s Acidic ribosomal protein Integrase_H2C2 PF17921.1 GBG64628.1 - 1.4e-13 50.7 1.0 2.5e-13 49.9 0.3 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG64628.1 - 2.6e-06 27.1 0.0 7.6e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG64628.1 - 0.03 14.6 0.0 0.089 13.1 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_5 PF14787.6 GBG64628.1 - 0.052 13.3 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-H2C2 PF09337.10 GBG64628.1 - 0.054 13.7 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger GAS PF13851.6 GBG64629.1 - 0.015 14.6 1.0 0.015 14.6 1.0 3.2 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.8 GBG64629.1 - 0.051 13.2 6.4 0.069 12.8 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) CTNNB1_binding PF08347.11 GBG64629.1 - 0.087 13.0 0.3 0.087 13.0 0.3 2.3 2 1 0 2 2 2 0 N-terminal CTNNB1 binding HTH_Tnp_1 PF01527.20 GBG64629.1 - 0.33 11.3 3.6 4.8 7.6 0.1 3.4 3 0 0 3 3 3 0 Transposase SHE3 PF17078.5 GBG64629.1 - 0.49 10.1 8.2 0.73 9.5 1.4 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF3450 PF11932.8 GBG64629.1 - 0.52 9.6 6.1 0.39 10.0 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 GBG64629.1 - 7 5.4 9.1 1.7 7.5 1.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein GIT_CC PF16559.5 GBG64629.1 - 7.5 6.5 8.3 0.7 9.8 1.0 2.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 GBG64629.1 - 7.7 6.8 13.9 1.1 9.5 0.4 4.0 4 1 0 4 4 4 0 Centrosomin N-terminal motif 1 DUF4187 PF13821.6 GBG64630.1 - 0.0007 19.3 0.8 0.002 17.8 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG64630.1 - 0.0065 16.7 1.1 0.03 14.6 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Lipin_mid PF16876.5 GBG64630.1 - 0.092 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Aa_trans PF01490.18 GBG64631.1 - 2.4e-15 56.2 22.9 8.9e-08 31.2 8.2 2.9 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein NOA36 PF06524.12 GBG64631.1 - 2 7.6 14.2 3.6 6.8 5.7 2.2 2 0 0 2 2 2 0 NOA36 protein AAA PF00004.29 GBG64632.1 - 1.4e-37 129.0 0.5 6.8e-36 123.6 0.0 3.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG64632.1 - 5e-10 39.0 0.0 1.5e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain SH3_12 PF18129.1 GBG64632.1 - 7.4e-06 26.0 2.1 4.4e-05 23.5 2.1 2.3 1 1 0 1 1 1 1 Xrn1 SH3-like domain FHA PF00498.26 GBG64632.1 - 2.1e-05 24.8 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain RuvB_N PF05496.12 GBG64632.1 - 8.7e-05 22.3 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG64632.1 - 0.00089 19.6 0.1 0.0057 16.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GBG64632.1 - 0.00095 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 GBG64632.1 - 0.0017 18.3 0.0 0.005 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG64632.1 - 0.0033 17.8 0.0 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 GBG64632.1 - 0.0039 16.4 0.3 0.008 15.4 0.2 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GBG64632.1 - 0.0082 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GBG64632.1 - 0.0083 15.5 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GBG64632.1 - 0.0091 16.0 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GBG64632.1 - 0.013 16.1 0.0 0.045 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GBG64632.1 - 0.018 14.2 0.0 0.37 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_2 PF07724.14 GBG64632.1 - 0.02 15.0 0.0 0.12 12.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 GBG64632.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GBG64632.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 GBG64632.1 - 0.081 13.2 0.2 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG64632.1 - 0.13 11.8 0.1 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GBG64632.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 GBG64632.1 - 0.19 11.1 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 GBG64632.1 - 0.21 11.5 0.1 0.54 10.2 0.1 1.7 1 0 0 1 1 1 0 NACHT domain MH1 PF03165.16 GBG64632.1 - 0.29 11.4 0.6 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 MH1 domain AAA PF00004.29 GBG64633.1 - 1.5e-37 129.0 0.6 6.8e-36 123.6 0.0 3.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG64633.1 - 5e-10 39.0 0.0 1.5e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain SH3_12 PF18129.1 GBG64633.1 - 7.4e-06 26.0 2.1 4.4e-05 23.5 2.1 2.2 1 1 0 1 1 1 1 Xrn1 SH3-like domain FHA PF00498.26 GBG64633.1 - 2.1e-05 24.8 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain RuvB_N PF05496.12 GBG64633.1 - 8.8e-05 22.3 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG64633.1 - 0.00088 19.6 0.1 0.0057 16.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GBG64633.1 - 0.00095 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 GBG64633.1 - 0.0019 18.2 0.0 0.005 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG64633.1 - 0.0033 17.8 0.0 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 GBG64633.1 - 0.0039 16.4 0.3 0.008 15.4 0.2 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GBG64633.1 - 0.0082 16.3 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GBG64633.1 - 0.0084 15.5 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GBG64633.1 - 0.0094 16.0 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GBG64633.1 - 0.013 16.1 0.0 0.045 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GBG64633.1 - 0.018 14.2 0.0 0.37 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_2 PF07724.14 GBG64633.1 - 0.024 14.7 0.1 0.12 12.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 GBG64633.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GBG64633.1 - 0.065 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 GBG64633.1 - 0.081 13.2 0.2 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG64633.1 - 0.13 11.8 0.1 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GBG64633.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 GBG64633.1 - 0.19 11.1 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Rad17 PF03215.15 GBG64633.1 - 0.2 11.6 0.0 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 GBG64633.1 - 0.2 11.5 0.1 0.54 10.2 0.1 1.7 1 0 0 1 1 1 0 NACHT domain MH1 PF03165.16 GBG64633.1 - 0.29 11.4 0.6 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 MH1 domain AAA PF00004.29 GBG64634.1 - 1.7e-37 128.8 0.6 6.8e-36 123.6 0.0 3.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG64634.1 - 5.1e-10 39.0 0.0 1.5e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain SH3_12 PF18129.1 GBG64634.1 - 7.6e-06 25.9 2.1 4.5e-05 23.5 2.1 2.2 1 1 0 1 1 1 1 Xrn1 SH3-like domain FHA PF00498.26 GBG64634.1 - 2.1e-05 24.8 0.0 4.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain RuvB_N PF05496.12 GBG64634.1 - 8.8e-05 22.3 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG64634.1 - 0.00091 19.5 0.1 0.0058 16.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GBG64634.1 - 0.00096 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 GBG64634.1 - 0.0019 18.2 0.0 0.005 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG64634.1 - 0.0033 17.8 0.0 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 GBG64634.1 - 0.004 16.4 0.3 0.008 15.4 0.2 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GBG64634.1 - 0.0083 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GBG64634.1 - 0.0084 15.5 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GBG64634.1 - 0.0097 15.9 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GBG64634.1 - 0.013 16.1 0.0 0.045 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 GBG64634.1 - 0.025 14.7 0.1 0.12 12.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 GBG64634.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GBG64634.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 GBG64634.1 - 0.068 13.4 0.2 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG64634.1 - 0.14 11.8 0.1 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GBG64634.1 - 0.14 11.3 0.0 0.37 9.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GBG64634.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 GBG64634.1 - 0.2 11.1 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Rad17 PF03215.15 GBG64634.1 - 0.2 11.5 0.0 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 GBG64634.1 - 0.21 11.5 0.1 0.54 10.2 0.1 1.7 1 0 0 1 1 1 0 NACHT domain MH1 PF03165.16 GBG64634.1 - 0.26 11.5 0.3 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 MH1 domain Ribosomal_S6 PF01250.17 GBG64635.1 - 2.9e-17 62.7 0.2 3.9e-17 62.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 CBS PF00571.28 GBG64636.1 - 2.5e-17 63.1 2.5 9.1e-08 32.4 0.1 2.5 2 0 0 2 2 2 2 CBS domain Integrase_H2C2 PF17921.1 GBG64637.1 - 5.5e-15 55.2 0.0 5.5e-15 55.2 0.0 2.6 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG64637.1 - 1.8e-11 44.2 0.0 4.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64637.1 - 1.8e-05 24.8 0.0 4.7e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG64637.1 - 3.5e-05 23.4 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG64637.1 - 0.012 16.3 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG64638.1 - 3.2e-24 85.2 0.0 7.7e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64638.1 - 1.2e-23 83.0 0.0 5.1e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64638.1 - 9.4e-11 41.6 0.2 6.5e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64638.1 - 2.1e-08 34.0 0.0 5.4e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG64638.1 - 6.4e-08 32.8 0.0 2.1e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG64638.1 - 6.9e-06 26.6 0.0 1.5e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG64638.1 - 0.00023 21.0 0.0 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 GBG64638.1 - 0.00035 20.4 0.0 0.00092 19.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain gag-asp_proteas PF13975.6 GBG64638.1 - 0.002 18.6 0.0 0.0049 17.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64638.1 - 0.071 12.9 0.0 0.17 11.6 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG64638.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF5523 PF17661.1 GBG64638.1 - 0.25 11.0 4.4 0.47 10.1 4.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) O-FucT PF10250.9 GBG64639.1 - 3.4e-66 224.3 0.0 6.7e-66 223.3 0.0 1.5 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase rve PF00665.26 GBG64639.1 - 7.1e-07 29.4 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG64639.1 - 2.1e-06 27.7 1.3 4.2e-06 26.8 1.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain YrbL-PhoP_reg PF10707.9 GBG64639.1 - 0.063 12.8 0.6 0.13 11.8 0.6 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DDHD PF02862.17 GBG64639.1 - 1.5 8.9 3.3 27 4.8 1.4 2.3 2 0 0 2 2 2 0 DDHD domain AAA_11 PF13086.6 GBG64639.1 - 6.5 6.4 9.3 0.5 10.1 1.1 2.2 2 0 0 2 2 2 0 AAA domain zf-CCHC PF00098.23 GBG64640.1 - 0.02 14.9 1.5 0.038 14.1 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG64641.1 - 3.7e-30 104.8 0.0 8.9e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64641.1 - 3e-05 23.7 0.0 7.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 GBG64643.1 - 9.9e-71 238.2 0.0 1.8e-33 116.1 0.0 4.3 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GBG64643.1 - 4.2e-70 236.0 0.0 6.1e-33 114.2 0.0 3.9 4 0 0 4 4 4 2 Protein tyrosine kinase RT_RNaseH_2 PF17919.1 GBG64643.1 - 1.1e-33 115.2 0.0 2.1e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64643.1 - 9.9e-31 107.0 0.1 2.2e-30 105.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64643.1 - 3.1e-30 104.5 0.0 6.3e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64643.1 - 4.8e-18 65.0 0.0 8.9e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64643.1 - 1.5e-13 51.0 0.0 4.1e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain APH PF01636.23 GBG64643.1 - 9.3e-06 25.7 0.0 0.23 11.4 0.0 3.3 2 2 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG64643.1 - 1e-05 24.5 0.0 0.062 12.1 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pup_ligase PF03136.15 GBG64643.1 - 0.023 13.8 1.8 1.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Pup-ligase protein Kdo PF06293.14 GBG64643.1 - 0.12 11.7 0.0 7.3 5.9 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dynamin_N PF00350.23 GBG64644.1 - 1.5e-07 31.6 1.9 2.4e-06 27.7 0.0 3.2 2 0 0 2 2 2 1 Dynamin family Na_trans_assoc PF06512.13 GBG64644.1 - 9.7e-05 22.7 0.5 9.7e-05 22.7 0.5 4.5 1 1 2 3 3 3 1 Sodium ion transport-associated MGDG_synth PF06925.11 GBG64644.1 - 0.24 11.5 0.4 0.62 10.2 0.3 1.7 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase DUF659 PF04937.15 GBG64645.1 - 3.5e-41 140.6 0.0 1e-40 139.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64645.1 - 0.01 15.6 0.3 0.077 12.8 0.2 2.3 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Pep_deformylase PF01327.21 GBG64645.1 - 0.071 12.7 2.0 0.38 10.4 0.1 2.4 2 0 0 2 2 2 0 Polypeptide deformylase AT_hook PF02178.19 GBG64645.1 - 0.48 10.5 8.1 0.45 10.5 3.9 2.8 2 0 0 2 2 2 0 AT hook motif GP88 PF17338.2 GBG64647.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Gene product 88 Wax2_C PF12076.8 GBG64648.1 - 1.5e-55 187.4 0.0 2e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 WAX2 C-terminal domain adh_short PF00106.25 GBG64648.1 - 0.00042 19.8 0.0 0.0006 19.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase PALP PF00291.25 GBG64648.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Elongin_A PF06881.11 GBG64649.1 - 1.2e-15 57.9 1.0 1.2e-15 57.9 1.0 2.6 2 1 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SUIM_assoc PF16619.5 GBG64649.1 - 0.011 15.7 3.6 0.011 15.7 3.6 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Coprogen_oxidas PF01218.18 GBG64650.1 - 2.7e-94 315.2 0.0 1.3e-71 240.8 0.0 2.1 1 1 1 2 2 2 2 Coproporphyrinogen III oxidase Myb_DNA-bind_4 PF13837.6 GBG64651.1 - 0.00075 19.8 3.0 0.00084 19.7 0.8 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain UDPGP PF01704.18 GBG64652.1 - 7.4e-42 143.4 0.0 1e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 GBG64652.1 - 0.092 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF659 PF04937.15 GBG64653.1 - 2e-13 50.5 0.0 3.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64653.1 - 0.073 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region OmdA PF13376.6 GBG64654.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated CTI PF06934.11 GBG64655.1 - 0.019 13.5 0.1 0.024 13.2 0.1 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) Telomerase_RBD PF12009.8 GBG64659.1 - 2.7e-29 102.0 0.1 4.2e-29 101.3 0.1 1.2 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 GBG64661.1 - 3.6e-62 209.8 0.2 3.3e-31 108.5 0.1 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64661.1 - 2.5e-34 117.2 3.3 1.2e-18 67.0 0.2 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG64661.1 - 1.1e-31 108.9 0.0 5.3e-24 84.1 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64661.1 - 2.8e-24 85.4 0.0 1.8e-23 82.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG64661.1 - 3.7e-19 69.1 0.0 1.3e-08 35.0 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain RVP_2 PF08284.11 GBG64661.1 - 4.2e-05 23.3 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG64661.1 - 5e-05 23.4 0.9 0.14 12.4 0.0 2.6 2 0 0 2 2 2 2 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG64661.1 - 0.0034 17.6 0.0 0.0034 17.6 0.0 4.8 5 0 0 5 5 5 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG64661.1 - 0.0036 17.9 0.0 0.38 11.4 0.0 2.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64661.1 - 0.016 15.8 0.0 0.56 10.8 0.0 2.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG64662.1 - 4.8e-31 106.7 0.0 9e-31 105.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64662.1 - 8.3e-29 100.7 0.1 1.4e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64662.1 - 1.4e-26 92.8 0.1 2.6e-26 92.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64662.1 - 3.6e-18 65.4 0.2 8.5e-18 64.2 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64662.1 - 5.2e-15 55.7 0.0 1.2e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64662.1 - 5.5e-05 23.3 0.0 0.0002 21.5 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger GFRP PF06399.13 GBG64663.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) PP1_inhibitor PF05361.12 GBG64663.1 - 3.2 7.7 9.0 10 6.1 0.7 2.8 1 1 1 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor CDC45 PF02724.14 GBG64665.1 - 0.6 8.3 22.6 0.81 7.9 22.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG64665.1 - 1 8.7 32.1 1.4 8.3 32.1 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG64665.1 - 1.6 8.4 25.4 2.3 7.9 25.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GBG64665.1 - 2.4 7.4 31.3 3.5 6.9 31.3 1.1 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 GBG64665.1 - 3.5 6.1 26.8 5 5.6 26.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lin-8 PF03353.15 GBG64665.1 - 5.7 6.4 19.9 8.3 5.9 19.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LAP1C PF05609.12 GBG64665.1 - 9.6 5.2 17.9 13 4.8 17.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Alpha-amyl_C2 PF07821.12 GBG64666.1 - 2.6e-18 66.0 0.1 5e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 GBG64666.1 - 4.6e-17 62.6 1.0 8.9e-16 58.4 1.0 2.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Nop14 PF04147.12 GBG64668.1 - 0.2 9.8 6.6 0.24 9.5 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG64668.1 - 0.94 8.8 9.7 1.2 8.5 9.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG64668.1 - 1.5 7.1 9.6 1.9 6.7 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 GBG64670.1 - 0.2 11.9 12.3 0.32 11.3 12.3 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG64670.1 - 0.29 9.4 7.6 0.34 9.2 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG64670.1 - 0.39 8.9 9.6 0.43 8.7 9.6 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG64670.1 - 0.39 10.1 9.1 0.43 9.9 9.1 1.1 1 0 0 1 1 1 0 SDA1 TAXi_N PF14543.6 GBG64671.1 - 4.3e-21 75.9 0.5 6.9e-21 75.3 0.5 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GBG64671.1 - 7.2e-13 48.6 0.9 3.8e-12 46.2 0.9 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GBG64671.1 - 5.6e-07 29.5 0.2 9.4e-07 28.7 0.2 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF659 PF04937.15 GBG64672.1 - 7.7e-32 110.3 0.1 1.2e-31 109.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) FYVE PF01363.21 GBG64672.1 - 0.13 12.4 1.5 0.28 11.4 1.5 1.4 1 0 0 1 1 1 0 FYVE zinc finger gag-asp_proteas PF13975.6 GBG64673.1 - 0.00094 19.7 0.0 0.012 16.1 0.0 2.3 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64673.1 - 0.049 14.3 0.0 0.15 12.7 0.0 1.9 1 1 0 1 1 1 0 Aspartyl protease ADP_ribosyl_GH PF03747.14 GBG64675.1 - 5.3e-37 128.1 1.8 6.7e-37 127.8 1.8 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase RT_RNaseH PF17917.1 GBG64676.1 - 4.9e-29 100.7 0.0 1.1e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64676.1 - 2.4e-28 98.1 0.0 5.1e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG64676.1 - 0.34 10.5 6.4 0.4 10.2 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3987 PF13148.6 GBG64676.1 - 6.4 5.7 10.1 1.2e+02 1.5 12.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) RT_RNaseH_2 PF17919.1 GBG64677.1 - 9.9e-28 96.1 0.0 1.7e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64677.1 - 9.2e-24 83.8 0.0 1.5e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64677.1 - 3.6e-08 33.2 0.1 5e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG64677.1 - 0.011 15.1 19.6 0.015 14.7 19.6 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG64677.1 - 0.21 9.8 13.8 0.31 9.3 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2249 PF10006.9 GBG64677.1 - 0.39 10.6 4.5 3.1 7.7 0.0 3.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) Nop14 PF04147.12 GBG64677.1 - 2.2 6.4 19.5 3.1 5.9 19.5 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG64677.1 - 2.8 6.6 7.1 5 5.8 7.1 1.4 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GBG64677.1 - 5.4 6.8 11.2 9.8 5.9 11.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.16 GBG64677.1 - 7.9 5.6 10.9 13 4.8 10.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DEK_C PF08766.11 GBG64678.1 - 0.0031 17.4 0.1 0.0064 16.4 0.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain SAP30_Sin3_bdg PF13867.6 GBG64679.1 - 5.4e-22 77.9 0.0 8.4e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Ribosomal_L35p PF01632.19 GBG64681.1 - 2.4e-19 69.6 11.1 5.1e-19 68.5 11.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L35 DUF659 PF04937.15 GBG64682.1 - 8.2e-32 110.2 0.0 1.9e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GWT1 PF06423.12 GBG64682.1 - 1.2e-31 109.9 0.0 4.9e-31 107.9 0.0 2.2 2 0 0 2 2 2 1 GWT1 rve PF00665.26 GBG64682.1 - 6.5e-15 55.4 0.1 9.1e-14 51.7 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG64682.1 - 2.7e-06 27.1 1.0 7e-06 25.7 1.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Macoilin PF09726.9 GBG64682.1 - 0.83 8.1 9.4 1.9 7.0 9.4 1.5 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 GBG64682.1 - 3.9 7.1 13.5 8 6.1 13.5 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 GREB1 PF15782.5 GBG64682.1 - 9.9 3.1 7.9 14 2.6 7.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EMC1_C PF07774.13 GBG64684.1 - 1.5e-59 201.3 0.6 1.7e-59 201.1 0.6 1.0 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal RT_RNaseH PF17917.1 GBG64685.1 - 1.6e-26 92.6 0.1 3.5e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64685.1 - 5.1e-21 74.6 0.1 1.2e-20 73.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64685.1 - 6.2e-18 64.7 0.3 1.5e-17 63.4 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64685.1 - 1e-15 57.9 0.0 3.4e-15 56.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64685.1 - 2.1e-05 24.6 0.0 5.8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG64685.1 - 0.003 17.8 0.4 0.014 15.6 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG64685.1 - 0.02 14.9 0.8 0.053 13.5 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF1564 PF07600.11 GBG64685.1 - 0.027 14.2 0.2 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-CCHC_4 PF14392.6 GBG64685.1 - 0.13 12.0 2.9 0.37 10.6 0.7 2.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC PF00098.23 GBG64685.1 - 1.5 9.1 4.7 2.8 8.2 4.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DASH_Duo1 PF08651.10 GBG64685.1 - 5.6 6.8 5.6 12 5.7 1.2 3.3 4 0 0 4 4 4 0 DASH complex subunit Duo1 RVT_1 PF00078.27 GBG64686.1 - 7e-30 104.2 0.1 1.3e-29 103.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64686.1 - 1.5e-24 85.9 0.0 8.8e-24 83.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64686.1 - 4e-16 59.2 0.0 1.3e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PQQ_2 PF13360.6 GBG64686.1 - 6e-11 42.4 5.8 2e-07 30.9 2.5 3.9 3 2 0 3 3 3 2 PQQ-like domain EMC1_C PF07774.13 GBG64686.1 - 1.8e-06 27.8 1.6 4.3e-06 26.6 0.1 2.2 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ PF01011.21 GBG64686.1 - 5.5e-05 22.9 2.8 0.069 13.1 0.0 4.4 6 0 0 6 6 6 2 PQQ enzyme repeat Chromo PF00385.24 GBG64686.1 - 0.01 15.7 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1664 PF07889.12 GBG64686.1 - 0.072 13.1 3.1 0.14 12.2 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RT_RNaseH_2 PF17919.1 GBG64688.1 - 8.7e-26 89.9 0.0 2.2e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64688.1 - 1.2e-22 80.2 0.0 8.7e-22 77.4 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG64688.1 - 0.017 15.4 0.1 0.066 13.5 0.0 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein DUF659 PF04937.15 GBG64690.1 - 1.8e-19 70.1 0.3 5.1e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Defensin_beta_2 PF13841.6 GBG64690.1 - 0.19 12.2 2.0 0.38 11.3 2.0 1.5 1 0 0 1 1 1 0 Beta defensin Pex14_N PF04695.13 GBG64690.1 - 4.5 7.9 9.2 1 10.0 1.2 2.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OST3_OST6 PF04756.13 GBG64691.1 - 7.3e-57 193.0 0.0 9.4e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Wzy_C PF04932.15 GBG64691.1 - 1.7 8.3 4.5 14 5.3 5.1 2.2 2 1 0 2 2 2 0 O-Antigen ligase RVT_1 PF00078.27 GBG64693.1 - 9.6e-09 35.1 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG64693.1 - 2.5e-05 24.8 0.1 5.3e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64693.1 - 0.00013 22.5 0.1 0.00032 21.3 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64693.1 - 0.0023 17.7 0.1 0.0041 16.9 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG64693.1 - 0.73 10.0 1.9 1.5 9.0 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG64694.1 - 3.2e-16 59.2 1.0 8.9e-16 57.7 1.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Peptidase_C48 PF02902.19 GBG64694.1 - 1.3e-14 54.6 1.2 2.7e-14 53.5 1.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Histone PF00125.24 GBG64694.1 - 7.3e-10 39.3 0.1 7.3e-10 39.3 0.1 5.7 6 1 1 7 7 7 1 Core histone H2A/H2B/H3/H4 gag-asp_proteas PF13975.6 GBG64694.1 - 0.0028 18.2 0.0 0.013 16.0 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG64694.1 - 0.0035 17.5 0.0 0.0092 16.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG64694.1 - 0.028 14.2 0.1 0.057 13.2 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF3367 PF11847.8 GBG64694.1 - 0.23 9.3 3.1 0.45 8.3 0.1 2.1 2 0 0 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase RVT_1 PF00078.27 GBG64695.1 - 9.8e-28 97.2 0.1 2e-27 96.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64695.1 - 5.8e-17 61.6 1.0 2.3e-16 59.6 1.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG64695.1 - 1.5e-11 44.5 0.0 4.4e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Hydrolase PF00702.26 GBG64695.1 - 1.6e-08 35.1 0.0 4e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase RT_RNaseH_2 PF17919.1 GBG64695.1 - 1.8e-08 34.3 0.0 5.4e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG64695.1 - 7.8e-07 29.7 0.0 1.9e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64695.1 - 8.3e-07 29.5 0.0 2.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease HAD_2 PF13419.6 GBG64695.1 - 1.4e-06 28.5 0.0 0.00081 19.5 0.0 2.8 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG64695.1 - 4e-06 26.8 0.0 1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like RVP_2 PF08284.11 GBG64695.1 - 0.00011 22.0 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG64695.1 - 0.00052 20.2 1.7 0.92 9.8 0.0 3.9 3 0 0 3 3 3 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG64695.1 - 0.0012 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG64695.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF659 PF04937.15 GBG64696.1 - 4.7e-05 23.3 0.0 9.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG64697.1 - 3.5e-05 24.3 0.0 8.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG64697.1 - 0.00098 19.4 0.0 0.0033 17.7 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64697.1 - 0.0013 19.4 0.0 0.0026 18.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64697.1 - 0.002 17.9 1.0 0.0068 16.2 0.1 2.2 3 0 0 3 3 3 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG64697.1 - 0.11 12.8 0.6 0.9 9.9 0.2 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein Rx_N PF18052.1 GBG64697.1 - 0.12 12.7 0.7 20 5.5 0.0 3.2 3 0 0 3 3 3 0 Rx N-terminal domain Integrase_H2C2 PF17921.1 GBG64698.1 - 2.5e-12 46.7 0.0 6.3e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64698.1 - 1.1e-10 41.7 0.0 3.7e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG64698.1 - 6.9e-05 23.3 0.0 0.00019 21.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64698.1 - 0.0022 18.6 0.0 0.0057 17.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG64698.1 - 0.0027 18.0 0.0 0.0073 16.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64698.1 - 0.0058 16.4 1.1 0.016 15.0 0.1 2.2 3 0 0 3 3 3 1 Aspartyl protease rve_3 PF13683.6 GBG64698.1 - 0.013 15.3 0.0 0.044 13.6 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain LicD PF04991.13 GBG64699.1 - 0.00041 20.6 18.5 0.00045 20.4 18.5 1.1 1 0 0 1 1 1 1 LicD family DUF2052 PF09747.9 GBG64699.1 - 0.029 14.5 19.3 0.032 14.4 19.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 GBG64699.1 - 0.045 13.6 27.8 0.047 13.5 27.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 GBG64699.1 - 0.16 12.3 19.7 0.17 12.1 19.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_pol_Rpc4 PF05132.14 GBG64699.1 - 0.21 12.0 18.4 0.3 11.5 18.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DDHD PF02862.17 GBG64699.1 - 0.27 11.3 10.7 0.35 11.0 10.7 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 GBG64699.1 - 0.49 10.4 10.5 0.5 10.4 10.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 GBG64699.1 - 0.66 8.9 19.9 0.67 8.9 19.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 AAA_11 PF13086.6 GBG64699.1 - 0.66 9.7 20.1 0.7 9.6 20.1 1.1 1 0 0 1 1 1 0 AAA domain CPSF100_C PF13299.6 GBG64699.1 - 0.78 9.9 17.1 1.2 9.2 17.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3807 PF12720.7 GBG64699.1 - 0.95 9.7 27.8 1.2 9.4 27.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF5308 PF17233.2 GBG64699.1 - 1.2 9.4 4.1 1.4 9.2 4.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SID-1_RNA_chan PF13965.6 GBG64699.1 - 1.3 7.3 7.6 1.4 7.3 7.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4228 PF14009.6 GBG64699.1 - 1.4 9.3 12.2 1.6 9.1 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) ALMT PF11744.8 GBG64699.1 - 2.5 6.8 16.5 2.5 6.8 16.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF853 PF05872.12 GBG64699.1 - 3.8 6.0 12.3 4.3 5.8 12.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CDC45 PF02724.14 GBG64699.1 - 4.2 5.5 25.6 4.6 5.4 25.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 GBG64699.1 - 5.3 5.0 14.3 5.3 5.0 14.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CSG2 PF16965.5 GBG64699.1 - 7 5.5 8.9 7.4 5.4 8.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator SpoIIP PF07454.11 GBG64699.1 - 7.2 6.0 23.6 9.5 5.6 23.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Gti1_Pac2 PF09729.9 GBG64699.1 - 7.4 6.6 21.9 8.8 6.4 21.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF3122 PF11320.8 GBG64700.1 - 0.043 13.9 0.8 0.38 10.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3122) YlzJ PF14035.6 GBG64700.1 - 0.074 13.3 0.7 1.2 9.4 0.1 2.1 1 1 1 2 2 2 0 YlzJ-like protein MOZART2 PF12926.7 GBG64700.1 - 0.13 11.9 4.0 0.32 10.6 1.1 2.1 1 1 1 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Dzip-like_N PF13815.6 GBG64700.1 - 0.26 11.3 7.1 0.78 9.7 2.6 2.3 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF659 PF04937.15 GBG64702.1 - 1.6e-25 89.7 0.0 2.8e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64702.1 - 1.2e-09 37.8 0.0 1.2e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region TPR_2 PF07719.17 GBG64704.1 - 8.1e-13 47.4 1.4 2.4e-06 27.2 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG64704.1 - 1.5e-11 44.6 6.6 3.7e-08 33.8 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG64704.1 - 1e-10 40.9 8.4 9.2e-07 28.4 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG64704.1 - 2.5e-10 39.7 4.7 3e-06 27.0 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG64704.1 - 4.2e-07 29.6 5.7 0.00086 19.1 0.7 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG64704.1 - 2e-06 28.1 7.3 0.021 15.6 0.0 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG64704.1 - 2.1e-06 27.3 0.1 0.0029 17.5 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG64704.1 - 1.9e-05 24.8 11.7 0.089 13.1 0.3 5.1 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 GBG64704.1 - 7.6e-05 23.0 0.3 2 9.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG64704.1 - 8e-05 23.0 3.4 4.1 8.3 0.0 4.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG64704.1 - 0.0002 21.9 0.7 0.8 10.4 0.1 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG64704.1 - 0.002 18.3 0.1 0.13 12.6 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GBG64704.1 - 0.0062 16.2 0.4 0.0062 16.2 0.4 2.7 2 1 0 2 2 2 1 TPR repeat Fis1_TPR_C PF14853.6 GBG64704.1 - 0.11 12.6 0.2 0.58 10.3 0.1 2.3 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat RVT_1 PF00078.27 GBG64705.1 - 6.1e-21 75.0 0.2 1.3e-20 73.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64705.1 - 8.5e-16 58.1 0.1 1.8e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64705.1 - 1.2e-08 34.9 0.0 3.1e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64705.1 - 4.9e-07 29.6 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64705.1 - 2.7e-05 24.7 0.0 7.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64705.1 - 0.00057 20.4 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64705.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG64706.1 - 2.7e-23 82.5 0.0 4.3e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64706.1 - 0.00085 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG64707.1 - 4.9e-24 84.3 0.0 9.8e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64707.1 - 5.7e-22 78.0 0.0 1.2e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64708.1 - 3.1e-52 177.3 2.6 3.4e-25 88.9 0.2 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64708.1 - 6.5e-20 71.0 0.0 3.4e-19 68.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64708.1 - 2.1e-18 66.5 0.0 5.1e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RRM_1 PF00076.22 GBG64708.1 - 2.9e-11 43.0 0.0 6.8e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVP_2 PF08284.11 GBG64708.1 - 2.4e-08 33.9 0.0 4.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64708.1 - 2.9e-07 31.0 0.0 7.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64708.1 - 2.4e-06 28.1 0.0 5.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64708.1 - 3.6e-05 23.6 0.0 7.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease PAM2 PF07145.15 GBG64708.1 - 0.00023 20.6 0.3 0.00059 19.3 0.3 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Retrotrans_gag PF03732.17 GBG64708.1 - 0.00068 19.9 0.2 0.0053 17.0 0.2 2.6 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG64709.1 - 5.5e-10 39.1 0.0 3.3e-05 23.7 0.0 2.9 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64709.1 - 3.3e-09 37.3 0.0 6.8e-05 23.4 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG64709.1 - 1.4e-05 25.6 0.0 0.03 14.9 0.0 3.8 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64709.1 - 6.8e-05 22.7 0.0 0.19 11.5 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease Retrotrans_gag PF03732.17 GBG64709.1 - 0.0021 18.3 1.0 0.094 13.0 0.0 3.6 4 0 0 4 4 4 1 Retrotransposon gag protein DUF1758 PF05585.12 GBG64709.1 - 0.0035 17.1 0.0 0.0094 15.7 0.0 1.7 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 GBG64711.1 - 6.8e-14 51.7 0.0 1.8e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64711.1 - 7.4e-12 45.5 0.0 1.8e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64711.1 - 1.1e-06 28.3 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pep_deformylase PF01327.21 GBG64711.1 - 0.038 13.6 0.7 0.09 12.4 0.7 1.6 1 0 0 1 1 1 0 Polypeptide deformylase DUF169 PF02596.15 GBG64711.1 - 0.058 13.3 0.2 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised ArCR, COG2043 MIB_HERC2 PF06701.13 GBG64711.1 - 0.13 12.5 1.5 0.36 11.1 0.2 2.4 2 0 0 2 2 2 0 Mib_herc2 Ribosomal_60s PF00428.19 GBG64711.1 - 1.6 9.4 19.5 1.8 9.2 11.4 3.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Presenilin PF01080.17 GBG64711.1 - 5.5 5.6 6.6 8 5.1 6.6 1.2 1 0 0 1 1 1 0 Presenilin zf-CCHC PF00098.23 GBG64712.1 - 2.7e-06 27.2 4.0 5e-06 26.3 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG64712.1 - 0.0074 16.2 0.7 0.018 15.0 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG64712.1 - 0.15 11.8 2.8 0.34 10.7 2.8 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger FHIPEP PF00771.20 GBG64712.1 - 3.1 6.2 5.7 4.2 5.7 5.7 1.2 1 0 0 1 1 1 0 FHIPEP family DUF659 PF04937.15 GBG64714.1 - 1.4e-32 112.6 0.0 2.3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64714.1 - 0.02 14.7 0.2 0.04 13.7 0.2 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF2109 PF09882.9 GBG64715.1 - 0.96 9.5 7.8 38 4.4 0.0 5.3 5 1 1 6 6 6 0 Predicted membrane protein (DUF2109) RT_RNaseH PF17917.1 GBG64717.1 - 3.3e-19 69.1 0.0 6e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64717.1 - 5.7e-18 64.8 0.0 1.4e-17 63.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Rap1_C PF11626.8 GBG64717.1 - 2.3 8.4 4.4 16 5.7 0.0 2.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain RVT_1 PF00078.27 GBG64719.1 - 6.9e-36 123.8 0.2 1e-28 100.4 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG64719.1 - 2.5e-09 37.3 0.0 9.1e-09 35.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG64719.1 - 2.2e-06 27.6 0.0 7.8e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64719.1 - 5.4e-06 26.2 0.0 0.024 14.4 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64719.1 - 1.3e-05 25.7 0.0 0.0012 19.5 0.0 3.2 3 0 0 3 3 3 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG64719.1 - 0.00013 22.0 0.1 0.00042 20.4 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG64719.1 - 0.0003 21.3 0.0 0.0016 18.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG64719.1 - 0.0016 18.7 0.3 0.013 15.8 0.1 2.8 2 1 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG64719.1 - 0.0019 18.1 0.1 0.0048 16.8 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG64719.1 - 0.0067 16.2 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG64720.1 - 4.3e-07 29.8 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG64720.1 - 5.2e-07 29.9 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG64720.1 - 1.4e-05 25.6 0.1 8.1e-05 23.2 0.0 2.3 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64720.1 - 2.7e-05 24.6 0.1 0.00026 21.5 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64720.1 - 2.9e-05 23.8 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG64720.1 - 0.21 11.5 1.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG64721.1 - 1.2e-20 73.8 0.0 5.4e-19 68.4 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG64721.1 - 2.8e-16 59.9 0.0 3.4e-07 30.8 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG64721.1 - 4.2e-16 58.8 0.0 3.8e-14 52.5 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG64721.1 - 2.9e-14 53.4 0.0 3e-06 27.7 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64721.1 - 2.5e-10 40.2 0.0 6.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64721.1 - 4.1e-08 33.1 0.0 0.0065 16.3 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease rve PF00665.26 GBG64721.1 - 0.00042 20.5 0.1 0.0027 17.9 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Gag_p24 PF00607.20 GBG64721.1 - 0.021 14.7 0.3 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) Retrotran_gag_2 PF14223.6 GBG64721.1 - 0.097 12.3 0.1 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF5523 PF17661.1 GBG64721.1 - 4.2 7.0 10.9 7.5 6.2 10.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RVT_1 PF00078.27 GBG64722.1 - 1.8e-26 93.1 0.3 3.3e-26 92.2 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64723.1 - 9e-14 51.3 0.0 2.5e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG64723.1 - 0.00085 19.8 0.0 0.0023 18.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG64723.1 - 0.0011 19.2 0.1 0.0043 17.3 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64723.1 - 0.0027 18.3 0.0 0.0074 16.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64723.1 - 0.034 14.0 0.1 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG64724.1 - 7.5e-21 74.0 0.0 1.6e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64724.1 - 4.2e-12 46.1 0.2 7.4e-12 45.2 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64724.1 - 6.2e-10 39.3 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SIMPL PF04402.14 GBG64724.1 - 0.18 12.3 6.0 0.05 14.0 2.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF541) JUPITER PF17054.5 GBG64724.1 - 0.21 11.0 4.2 0.33 10.4 4.2 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter DUF1633 PF07794.11 GBG64724.1 - 1.5 6.9 9.4 0.53 8.4 6.7 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1633) DUF659 PF04937.15 GBG64725.1 - 3.6e-32 111.3 0.1 5.7e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG64726.1 - 6.8e-17 61.7 0.0 1.5e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64726.1 - 2.2e-09 37.2 0.0 8.1e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64726.1 - 4.5e-09 36.8 0.0 2.5e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64726.1 - 1.1e-06 29.1 0.0 4.4e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG64726.1 - 0.0075 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease WD40_alt PF14077.6 GBG64726.1 - 0.081 12.8 0.2 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif Retrotrans_gag PF03732.17 GBG64726.1 - 0.15 12.4 2.7 0.36 11.1 0.1 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein FAM76 PF16046.5 GBG64726.1 - 0.4 10.0 7.5 0.66 9.3 7.5 1.2 1 0 0 1 1 1 0 FAM76 protein RT_RNaseH_2 PF17919.1 GBG64727.1 - 7.6e-25 86.9 0.0 1.3e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64727.1 - 1.2e-12 48.1 0.0 2.4e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64727.1 - 2.6e-08 33.6 0.1 4e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG64727.1 - 0.00015 22.2 0.0 0.00047 20.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64727.1 - 0.00018 22.1 0.0 0.00041 20.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64727.1 - 0.0031 17.3 0.5 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG64727.1 - 0.036 13.9 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG64727.1 - 0.076 12.8 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG64729.1 - 9.6e-07 29.4 0.0 2.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64729.1 - 5.6e-06 26.8 0.0 1.6e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64729.1 - 3e-05 23.8 0.0 7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64729.1 - 0.0001 22.1 0.0 0.00034 20.4 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG64729.1 - 0.0011 19.1 0.2 0.0011 19.1 0.2 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4916 PF16262.5 GBG64729.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) Mt_ATP-synt_B PF05405.14 GBG64729.1 - 4.8 6.8 7.1 5.2 6.7 5.9 1.7 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Caudo_TAP PF02413.17 GBG64729.1 - 5.3 7.2 10.7 0.89 9.7 1.2 2.7 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK NIF PF03031.18 GBG64730.1 - 2.5e-36 124.8 0.0 2.9e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DsrH PF04077.12 GBG64731.1 - 9.7e-05 22.4 0.8 12 6.1 0.0 5.8 2 2 6 8 8 8 1 DsrH like protein CstA PF02554.14 GBG64731.1 - 0.0022 17.0 7.5 3.3 6.5 0.0 4.4 3 1 2 5 5 5 3 Carbon starvation protein CstA XendoU PF09412.10 GBG64731.1 - 3.4 6.8 14.9 14 4.8 0.9 4.0 1 1 2 4 4 4 0 Endoribonuclease XendoU HTH_Tnp_1 PF01527.20 GBG64731.1 - 3.6 8.0 8.9 13 6.2 0.4 3.7 3 2 0 3 3 3 0 Transposase SAP PF02037.27 GBG64732.1 - 0.0012 18.5 0.0 0.0038 16.9 0.0 1.9 1 0 0 1 1 1 1 SAP domain SR-25 PF10500.9 GBG64732.1 - 0.0051 16.5 32.8 0.0082 15.8 32.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3786 PF12654.7 GBG64732.1 - 0.11 12.0 0.2 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) SpoIIIAH PF12685.7 GBG64732.1 - 0.23 11.2 20.9 16 5.3 22.1 2.1 1 1 1 2 2 2 0 SpoIIIAH-like protein SRP-alpha_N PF04086.13 GBG64732.1 - 0.51 10.2 22.1 0.57 10.1 22.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3275 PF11679.8 GBG64732.1 - 1.5 8.7 6.5 2.2 8.2 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Membralin PF09746.9 GBG64732.1 - 1.7 7.6 6.6 2.2 7.3 6.6 1.3 1 0 0 1 1 1 0 Tumour-associated protein CRT10 PF08728.10 GBG64732.1 - 2.1 6.4 11.4 2.3 6.3 11.4 1.0 1 0 0 1 1 1 0 CRT10 DUF3112 PF11309.8 GBG64732.1 - 3 7.3 4.0 4.7 6.6 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Antimicrobial15 PF08110.12 GBG64733.1 - 0.51 10.7 2.4 14 6.1 0.2 2.6 2 0 0 2 2 2 0 Ocellatin family Pannexin_like PF12534.8 GBG64733.1 - 4.2 6.4 8.5 0.22 10.6 2.3 1.8 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Orn_Arg_deC_N PF02784.16 GBG64734.1 - 8.8e-47 159.5 0.0 1.1e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Ala_racemase_N PF01168.20 GBG64734.1 - 3.1e-07 30.3 0.1 8.5e-07 28.8 0.0 1.7 2 1 0 2 2 2 1 Alanine racemase, N-terminal domain Me-amine-dh_L PF02975.14 GBG64734.1 - 0.17 12.4 0.1 0.33 11.5 0.1 1.4 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Dimer_Tnp_hAT PF05699.14 GBG64735.1 - 6.8e-08 32.2 0.1 1.6e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG64735.1 - 4.8e-05 23.3 0.0 0.0017 18.2 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) Orn_DAP_Arg_deC PF00278.22 GBG64736.1 - 1.2e-23 83.1 0.0 1.4e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain RVT_1 PF00078.27 GBG64736.1 - 5.5e-10 39.1 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64738.1 - 5.2e-20 71.3 0.0 1.2e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64738.1 - 4e-19 68.8 0.0 1.1e-18 67.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG64738.1 - 0.005 17.4 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64738.1 - 0.0059 17.2 0.0 0.017 15.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG64738.1 - 0.013 15.3 1.0 0.02 14.7 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle Rx_N PF18052.1 GBG64738.1 - 0.022 15.0 0.9 52 4.2 0.0 3.9 4 0 0 4 4 4 0 Rx N-terminal domain Retrotrans_gag PF03732.17 GBG64738.1 - 0.024 14.9 0.2 0.19 12.0 0.1 2.5 1 1 1 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 GBG64738.1 - 0.026 14.8 0.0 0.087 13.1 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG64738.1 - 0.38 10.9 1.5 0.69 10.1 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG64739.1 - 1.8e-30 105.3 0.0 4.7e-30 104.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64739.1 - 1.9e-30 104.8 0.0 3.9e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64739.1 - 2.4e-18 66.0 0.4 6.5e-18 64.6 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64739.1 - 1.7e-16 60.5 0.0 4.2e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64739.1 - 0.00022 21.4 0.0 0.00063 19.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Saccharop_dh_N PF04455.12 GBG64739.1 - 0.19 12.2 1.3 1.1 9.7 0.1 2.8 3 0 0 3 3 3 0 LOR/SDH bifunctional enzyme conserved region RNase_H PF00075.24 GBG64739.1 - 0.2 11.8 1.1 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 RNase H Casc1_N PF15927.5 GBG64739.1 - 0.23 11.1 17.2 0.5 10.0 17.2 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus PPR_2 PF13041.6 GBG64741.1 - 1e-52 176.1 17.2 5.6e-11 42.5 0.2 10.8 4 3 6 10 10 10 10 PPR repeat family PPR_3 PF13812.6 GBG64741.1 - 2e-42 143.1 0.4 6.2e-10 39.0 0.0 6.7 5 2 0 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 GBG64741.1 - 1.3e-37 125.4 18.8 0.00021 21.3 0.0 11.3 12 0 0 12 12 12 8 PPR repeat PPR_1 PF12854.7 GBG64741.1 - 1.3e-32 111.2 0.1 9.2e-05 22.1 0.0 9.9 10 0 0 10 10 10 6 PPR repeat PPR_long PF17177.4 GBG64741.1 - 1.7e-30 106.0 5.1 1.3e-13 50.8 0.0 3.6 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 GBG64741.1 - 3.8e-05 23.5 0.3 0.89 9.4 0.0 4.6 3 1 2 5 5 5 1 Mitochondrial ATPase expression TPR_19 PF14559.6 GBG64741.1 - 0.00032 21.1 2.9 0.025 15.1 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Clathrin PF00637.20 GBG64741.1 - 0.012 15.5 0.2 0.36 10.7 0.0 3.2 3 1 1 4 4 4 0 Region in Clathrin and VPS SCAB-PH PF17684.1 GBG64741.1 - 0.094 13.0 0.4 3.8 7.8 0.0 3.0 3 0 0 3 3 3 0 PH domain of plant-specific actin-binding protein FA_desaturase PF00487.24 GBG64743.1 - 1.4e-22 80.8 23.9 2.1e-22 80.2 23.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase G-alpha PF00503.20 GBG64746.1 - 1.2e-102 343.7 0.6 1.5e-102 343.4 0.6 1.1 1 0 0 1 1 1 1 G-protein alpha subunit FAA_hydrolase PF01557.18 GBG64746.1 - 3.1e-54 183.9 0.0 5e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GBG64746.1 - 2.7e-23 82.2 0.0 7.3e-23 80.8 0.0 1.8 1 1 0 1 1 1 1 Fumarylacetoacetase N-terminal Arf PF00025.21 GBG64746.1 - 9.5e-14 51.2 0.7 1.4e-10 40.9 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GBG64746.1 - 0.00094 18.6 0.7 0.16 11.3 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GBG64746.1 - 0.099 12.9 0.2 3.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Fer4_14 PF13394.6 GBG64746.1 - 0.15 12.2 2.3 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain PBP1_TM PF14812.6 GBG64747.1 - 0.16 12.3 15.1 0.52 10.7 15.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYDLN_acid PF09538.10 GBG64747.1 - 6 7.6 16.0 5.4 7.7 6.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) AP3D1 PF06375.11 GBG64747.1 - 6.5 7.0 11.2 0.27 11.5 4.7 1.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Prothymosin PF03247.14 GBG64747.1 - 9.4 6.7 24.3 11 6.5 7.4 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family PI31_Prot_N PF11566.8 GBG64748.1 - 4.8e-15 55.7 0.0 9.1e-15 54.8 0.0 1.4 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 GBG64748.1 - 3.6e-08 34.5 20.3 3.6e-08 34.5 20.3 3.3 3 2 0 3 3 3 1 PI31 proteasome regulator zf-CCHC PF00098.23 GBG64749.1 - 0.019 15.1 1.1 0.063 13.4 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG64749.1 - 0.019 14.8 2.4 0.019 14.8 2.4 2.1 2 0 0 2 2 2 0 Zinc knuckle OrfB_IS605 PF01385.19 GBG64749.1 - 0.12 12.6 10.8 3.1 8.0 0.3 2.5 2 0 0 2 2 2 0 Probable transposase DUF4681 PF15732.5 GBG64749.1 - 0.7 10.2 6.4 0.55 10.5 4.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4681) Arm PF00514.23 GBG64750.1 - 7.4e-33 111.6 7.0 1.9e-07 30.9 0.0 7.1 7 0 0 7 7 7 6 Armadillo/beta-catenin-like repeat U-box PF04564.15 GBG64750.1 - 1.2e-19 70.3 0.0 2.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain KAP PF05804.12 GBG64750.1 - 1.1e-06 27.1 0.1 4.3e-06 25.2 0.0 1.9 2 1 0 2 2 2 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 GBG64750.1 - 1.8e-06 27.6 0.0 1.6e-05 24.5 0.0 2.3 1 1 1 2 2 2 1 Armadillo-like RPW8 PF05659.11 GBG64750.1 - 2.1e-06 27.5 2.8 4.7e-06 26.3 2.8 1.6 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 zf-Nse PF11789.8 GBG64750.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HEAT_2 PF13646.6 GBG64750.1 - 0.017 15.5 7.6 0.54 10.7 0.6 4.3 1 1 3 4 4 4 0 HEAT repeats DUF1129 PF06570.11 GBG64750.1 - 0.18 11.3 1.6 0.32 10.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1664 PF07889.12 GBG64750.1 - 8.2 6.5 7.5 3.5 7.7 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Arm PF00514.23 GBG64751.1 - 1.2e-30 104.6 5.1 5.1e-08 32.7 0.0 6.0 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat RT_RNaseH PF17917.1 GBG64751.1 - 9.9e-30 102.9 0.2 2.1e-29 101.9 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64751.1 - 1.1e-23 83.2 0.0 2.2e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64751.1 - 5.8e-20 71.2 0.1 2.2e-19 69.3 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64751.1 - 1.9e-10 41.0 0.1 4e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain KAP PF05804.12 GBG64751.1 - 8.1e-06 24.3 0.1 3e-05 22.4 0.1 1.8 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) zf-H2C2 PF09337.10 GBG64751.1 - 0.00066 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Arm_2 PF04826.13 GBG64751.1 - 0.0019 17.7 0.1 0.0081 15.6 0.1 2.0 2 0 0 2 2 2 1 Armadillo-like DUF1564 PF07600.11 GBG64751.1 - 0.068 12.9 0.4 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DUF547 PF04784.14 GBG64752.1 - 1e-37 128.9 0.0 2e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Glutaredoxin PF00462.24 GBG64752.1 - 1.2e-18 67.1 0.0 2.4e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DEP PF00610.21 GBG64752.1 - 5.3e-05 23.2 0.0 0.00019 21.4 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GST_N_3 PF13417.6 GBG64752.1 - 0.00035 20.9 0.0 0.00094 19.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG64752.1 - 0.0017 18.6 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 GBG64752.1 - 0.0067 16.8 0.0 0.021 15.3 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 GBG64752.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.6 GBG64752.1 - 0.16 12.5 0.0 0.45 11.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain rve PF00665.26 GBG64753.1 - 2.9e-13 50.0 0.0 6.2e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain eIF-1a PF01176.19 GBG64753.1 - 0.011 15.5 0.1 0.029 14.2 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 CCD48 PF15799.5 GBG64753.1 - 0.12 10.7 1.6 0.17 10.2 1.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Chromo PF00385.24 GBG64753.1 - 0.12 12.2 0.1 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain HALZ PF02183.18 GBG64753.1 - 0.35 11.1 1.6 0.77 10.0 1.6 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 GBG64753.1 - 2.1 8.5 9.1 0.071 13.2 3.0 1.8 2 0 0 2 2 2 0 Basic region leucine zipper Actin PF00022.19 GBG64754.1 - 6e-145 482.9 0.0 6.9e-145 482.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GBG64754.1 - 8.5e-08 31.4 0.0 7.6e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Ppx-GppA PF02541.16 GBG64754.1 - 0.019 14.4 0.3 0.04 13.4 0.0 1.6 2 0 0 2 2 2 0 Ppx/GppA phosphatase family FtsA PF14450.6 GBG64754.1 - 0.1 13.0 0.8 0.47 10.9 0.2 2.4 2 1 0 2 2 2 0 Cell division protein FtsA CTD_bind PF04818.13 GBG64755.1 - 5.8e-15 55.9 0.1 1.3e-14 54.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 GBG64755.1 - 0.096 12.9 2.6 0.2 11.8 2.6 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour TEX13 PF15186.6 GBG64755.1 - 1 9.0 3.5 2.5 7.8 3.5 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Raffinose_syn PF05691.12 GBG64756.1 - 7.9e-240 797.7 0.0 3.6e-201 669.8 0.0 3.9 3 1 0 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 TPR_12 PF13424.6 GBG64757.1 - 4.1e-14 52.6 15.1 1.7e-06 28.2 0.2 5.8 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG64757.1 - 3.5e-05 23.4 9.4 6.9 6.7 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG64757.1 - 0.00016 21.5 12.3 9.7 6.6 0.3 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 GBG64757.1 - 0.00021 21.0 12.1 0.31 11.0 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat SNAP PF14938.6 GBG64757.1 - 0.0015 18.0 1.0 0.0037 16.7 0.2 1.9 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 GBG64757.1 - 0.0017 18.4 9.4 7.3 7.1 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat ROS_MUCR PF05443.11 GBG64757.1 - 0.038 14.0 0.4 1.2 9.2 0.1 3.0 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein TPR_9 PF13371.6 GBG64757.1 - 0.13 12.4 0.7 0.65 10.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat FAM176 PF14851.6 GBG64757.1 - 0.54 9.9 8.2 1.7 8.3 8.2 1.9 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 GBG64757.1 - 4.8 5.3 15.8 8.7 4.4 15.8 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.9 GBG64757.1 - 7.8 6.6 21.6 1.5 8.9 16.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TPR_12 PF13424.6 GBG64758.1 - 8.7e-15 54.8 19.4 1.3e-06 28.6 0.2 5.8 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 GBG64758.1 - 2.3e-06 27.2 14.0 0.22 11.4 0.7 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG64758.1 - 6.3e-06 25.9 15.5 1.7 9.0 0.5 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 GBG64758.1 - 0.00011 22.0 12.7 0.23 11.4 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat SNAP PF14938.6 GBG64758.1 - 0.0009 18.7 1.1 0.0027 17.2 0.2 2.0 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 GBG64758.1 - 0.0022 18.0 13.2 5.5 7.5 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat ROS_MUCR PF05443.11 GBG64758.1 - 0.017 15.2 0.4 0.87 9.6 0.1 3.2 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein TPR_9 PF13371.6 GBG64758.1 - 0.068 13.3 0.7 0.47 10.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat FAM176 PF14851.6 GBG64758.1 - 0.26 10.9 7.8 0.91 9.2 7.8 2.0 1 0 0 1 1 1 0 FAM176 family MIT PF04212.18 GBG64758.1 - 0.32 11.1 4.9 22 5.2 0.0 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain WD40 PF00400.32 GBG64759.1 - 2.5e-09 37.6 4.6 9.1e-05 23.2 0.3 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG64759.1 - 1.8e-08 34.6 0.0 0.043 14.1 0.0 3.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain zf-CCHC PF00098.23 GBG64759.1 - 0.031 14.4 2.1 0.034 14.2 0.4 2.0 2 0 0 2 2 2 0 Zinc knuckle Ge1_WD40 PF16529.5 GBG64759.1 - 0.072 12.0 0.0 0.26 10.2 0.0 1.9 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Kri1_C PF12936.7 GBG64760.1 - 4.1e-25 87.8 1.2 4.1e-25 87.8 1.2 5.7 6 1 1 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.12 GBG64760.1 - 6.7e-05 23.4 32.3 6.7e-05 23.4 32.3 9.7 8 4 1 9 9 9 1 KRI1-like family rRNA_proc-arch PF13234.6 GBG64761.1 - 1.3e-67 228.6 3.5 1.8e-67 228.1 3.5 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 GBG64761.1 - 2.3e-37 128.2 0.1 4.4e-19 68.7 0.0 2.8 1 1 1 2 2 2 2 DSHCT (NUC185) domain DEAD PF00270.29 GBG64761.1 - 1.3e-17 64.1 0.0 7e-17 61.7 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 GBG64761.1 - 6.7e-06 26.2 0.0 2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF724 PF05266.14 GBG64761.1 - 0.12 12.2 4.0 0.054 13.3 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF872 PF05915.12 GBG64762.1 - 4.2e-19 68.8 2.1 4.5e-19 68.7 2.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Neurensin PF14927.6 GBG64762.1 - 0.076 12.7 1.0 2.3 7.9 0.1 2.0 2 0 0 2 2 2 0 Neurensin Glyco_transf_29 PF00777.18 GBG64763.1 - 2.2e-34 119.1 0.3 1.1e-32 113.5 0.3 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) EssA PF10661.9 GBG64763.1 - 0.098 12.5 0.8 0.22 11.3 0.8 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA KIAA1430 PF13879.6 GBG64764.1 - 0.0032 18.2 3.6 0.0032 18.2 3.6 1.8 1 1 0 1 1 1 1 KIAA1430 homologue DDE_Tnp_4 PF13359.6 GBG64765.1 - 3.4e-29 101.6 0.1 8.2e-29 100.3 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64765.1 - 0.00018 21.2 0.0 0.00083 19.0 0.0 1.9 1 1 0 1 1 1 1 Plant transposon protein DUF5069 PF16798.5 GBG64765.1 - 0.034 14.4 5.2 0.035 14.3 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) HsdM_N PF12161.8 GBG64765.1 - 0.043 14.4 7.8 1.7 9.2 0.5 2.5 2 0 0 2 2 2 0 HsdM N-terminal domain DUF1280 PF06918.14 GBG64765.1 - 0.45 10.1 3.7 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1280) DUF1664 PF07889.12 GBG64765.1 - 0.61 10.1 4.6 0.28 11.2 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) EssA PF10661.9 GBG64765.1 - 9.1 6.1 7.7 0.32 10.8 0.9 2.0 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein EssA BATS PF06968.13 GBG64766.1 - 7.2e-24 83.7 0.0 1.6e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 GBG64766.1 - 5e-07 30.2 0.3 3.7e-06 27.4 0.1 2.7 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 GBG64766.1 - 0.023 14.8 0.2 0.067 13.3 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Myb_DNA-bind_4 PF13837.6 GBG64767.1 - 0.00014 22.2 0.4 0.00026 21.3 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain NTP_transf_9 PF04248.12 GBG64767.1 - 0.11 12.4 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF427) DUF4140 PF13600.6 GBG64769.1 - 1.2 9.6 5.8 2.2 8.7 3.8 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HTH_Tnp_1 PF01527.20 GBG64769.1 - 2.2 8.6 10.2 3.4 8.1 5.2 3.1 3 1 0 3 3 3 0 Transposase Rpn3_C PF08375.11 GBG64769.1 - 3.1 8.3 7.6 0.48 10.9 3.0 2.1 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal Atrophin-1 PF03154.15 GBG64769.1 - 3.1 5.9 7.2 5.3 5.2 7.2 1.4 1 0 0 1 1 1 0 Atrophin-1 family Vps16_C PF04840.12 GBG64770.1 - 6.3e-59 199.6 0.1 1.7e-52 178.5 0.0 2.1 1 1 1 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.13 GBG64770.1 - 6.2e-49 166.9 0.0 2.5e-37 128.6 0.0 2.2 2 0 0 2 2 2 2 Vps16, N-terminal region ANAPC4_WD40 PF12894.7 GBG64770.1 - 0.0048 17.2 0.0 0.52 10.6 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.14 GBG64770.1 - 0.0065 14.8 1.5 0.011 14.1 1.5 1.4 1 0 0 1 1 1 1 CDC45-like protein IKI3 PF04762.12 GBG64770.1 - 0.23 9.4 0.0 0.38 8.7 0.0 1.3 1 0 0 1 1 1 0 IKI3 family DUF2201_N PF13203.6 GBG64770.1 - 5.4 6.5 5.9 10 5.6 5.9 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.12 GBG64770.1 - 7.9 4.6 17.4 12 3.9 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family GPHR_N PF12537.8 GBG64771.1 - 0.022 14.8 0.9 7.2 6.8 0.0 3.1 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Spc7 PF08317.11 GBG64771.1 - 0.1 11.4 28.9 0.51 9.2 14.4 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 GBG64771.1 - 0.21 11.7 39.1 0.31 11.1 10.6 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Apt1 PF10351.9 GBG64771.1 - 0.32 9.8 12.3 0.092 11.6 4.8 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain OmpH PF03938.14 GBG64771.1 - 0.72 10.2 28.0 0.41 11.0 2.8 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 GBG64771.1 - 1.5 9.4 34.6 2.8 8.5 9.1 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 GBG64771.1 - 5.7 7.0 14.0 19 5.3 1.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) tRNA-synt_2 PF00152.20 GBG64772.1 - 1.4e-75 254.3 0.0 2.7e-57 194.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GBG64772.1 - 2.2e-15 56.4 0.2 4.4e-15 55.4 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GBG64772.1 - 1.5e-05 24.6 0.4 0.027 13.9 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF2967 PF11179.8 GBG64772.1 - 8.8 4.3 11.1 1.8 6.6 7.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) GPI2 PF06432.11 GBG64773.1 - 0.57 9.6 2.8 0.74 9.2 2.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3487 PF11990.8 GBG64773.1 - 4.6 7.1 7.2 8.1 6.4 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) WD40 PF00400.32 GBG64774.1 - 3.8e-15 56.0 10.3 0.37 11.8 0.2 7.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG64774.1 - 3.7e-06 27.2 0.0 2.3 8.6 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BRK PF07533.16 GBG64774.1 - 0.03 13.9 0.0 3.3 7.4 0.0 3.6 4 0 0 4 4 4 0 BRK domain RT_RNaseH_2 PF17919.1 GBG64775.1 - 8.6e-23 80.3 0.0 2.9e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64775.1 - 8.7e-22 77.7 0.1 6.9e-10 38.8 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64775.1 - 3.1e-21 75.6 0.0 1e-20 74.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG64775.1 - 2.7e-07 31.1 0.1 6.1e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64775.1 - 7.4e-05 23.3 0.1 0.00015 22.4 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64775.1 - 0.0063 16.3 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Aminotran_1_2 PF00155.21 GBG64776.1 - 3.9e-57 194.1 0.0 4.4e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GBG64776.1 - 2e-06 26.6 0.0 2.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 GBG64776.1 - 3.7e-05 23.2 0.0 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GBG64776.1 - 0.00024 20.6 0.0 0.00034 20.0 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family gag-asp_proteas PF13975.6 GBG64777.1 - 4.4e-10 40.0 0.0 1.6e-09 38.2 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64777.1 - 1.6e-05 25.4 0.0 4.9e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG64777.1 - 0.0019 18.5 0.0 0.0066 16.7 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64777.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease GRP PF07172.11 GBG64777.1 - 0.035 14.8 22.3 0.13 12.9 22.3 2.0 1 0 0 1 1 1 0 Glycine rich protein family KH_4 PF13083.6 GBG64777.1 - 0.036 13.9 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 KH domain TraI_2 PF07514.11 GBG64777.1 - 0.066 12.1 0.1 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative helicase TFIIS_C PF01096.18 GBG64777.1 - 0.83 9.6 2.8 12 5.9 0.4 2.9 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_10 PF16588.5 GBG64778.1 - 0.064 13.0 3.5 0.13 12.1 3.5 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 GBG64778.1 - 0.16 11.7 0.7 0.35 10.6 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG64778.1 - 3.8 7.4 5.5 5.6 6.9 5.5 1.2 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG64779.1 - 1.4e-06 28.0 0.0 4.1e-06 26.5 0.0 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG64780.1 - 0.00032 20.5 0.0 0.0008 19.3 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TMF_TATA_bd PF12325.8 GBG64780.1 - 0.0019 18.4 12.1 0.0019 18.4 12.1 19.3 7 5 13 20 20 20 3 TATA element modulatory factor 1 TATA binding Choline_transpo PF04515.12 GBG64781.1 - 6.3e-09 35.5 19.7 2.2e-08 33.7 19.7 2.1 1 1 0 1 1 1 1 Plasma-membrane choline transporter GCIP PF13324.6 GBG64782.1 - 0.049 13.2 4.7 0.052 13.1 4.7 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FAM176 PF14851.6 GBG64782.1 - 0.18 11.5 5.3 0.22 11.2 5.3 1.3 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.11 GBG64782.1 - 0.2 10.2 6.1 0.19 10.2 6.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFB6 PF17110.5 GBG64782.1 - 0.28 10.9 4.6 0.34 10.6 4.6 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sporozoite_P67 PF05642.11 GBG64782.1 - 0.42 8.7 6.0 0.49 8.4 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 GBG64782.1 - 0.43 10.3 16.2 0.54 9.9 16.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG64782.1 - 0.57 9.6 12.6 0.54 9.6 12.6 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 GBG64782.1 - 0.91 8.8 19.8 1.1 8.6 19.8 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 GBG64782.1 - 1.2 8.2 19.1 1.3 8.1 19.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GBG64782.1 - 1.7 6.6 16.9 1.9 6.5 16.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 GBG64782.1 - 2 8.5 15.1 2.5 8.1 15.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PGA2 PF07543.12 GBG64782.1 - 2 8.4 11.5 2.9 7.9 11.5 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Trypan_PARP PF05887.11 GBG64782.1 - 2.3 8.2 5.7 3 7.8 5.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 GBG64782.1 - 3.4 5.9 11.4 3.5 5.8 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG64782.1 - 6.4 4.9 15.2 6.7 4.8 15.2 1.1 1 0 0 1 1 1 0 Nop14-like family GBP_C PF02841.14 GBG64783.1 - 0.11 11.9 14.2 0.17 11.3 14.2 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain ANAPC15 PF15243.6 GBG64783.1 - 0.17 12.3 0.3 0.17 12.3 0.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 AAA_11 PF13086.6 GBG64783.1 - 0.32 10.7 6.3 0.6 9.8 6.3 1.4 1 0 0 1 1 1 0 AAA domain RVP_2 PF08284.11 GBG64784.1 - 1.7e-05 24.6 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64784.1 - 0.0002 21.9 0.1 0.00054 20.5 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64784.1 - 0.0002 21.9 0.0 0.00084 19.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 GBG64784.1 - 0.00039 20.4 2.8 0.0007 19.6 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 GBG64784.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG64784.1 - 0.025 14.4 2.3 0.043 13.7 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Gb3_synth PF04572.12 GBG64785.1 - 1.4e-17 64.0 1.6 2e-07 31.3 0.6 2.7 2 0 0 2 2 2 2 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 GBG64785.1 - 5e-15 55.9 0.0 1e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Dynamin_M PF01031.20 GBG64786.1 - 1.8e-58 198.0 0.0 4.7e-29 101.5 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 GBG64786.1 - 1.2e-49 168.6 0.0 1.5e-32 113.0 0.0 2.7 2 0 0 2 2 2 2 Dynamin family GED PF02212.18 GBG64786.1 - 2.9e-15 56.2 7.1 2.2e-07 31.0 0.3 3.1 2 0 0 2 2 2 2 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GBG64786.1 - 2.5e-05 24.3 2.4 0.051 13.7 0.2 4.4 3 1 0 3 3 3 2 50S ribosome-binding GTPase TniB PF05621.11 GBG64786.1 - 0.0035 16.8 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein Roc PF08477.13 GBG64786.1 - 0.006 16.8 1.0 1.8 8.8 0.1 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 GBG64786.1 - 0.012 15.3 0.3 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 GBG64786.1 - 0.024 14.1 0.2 11 5.4 0.0 3.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 GBG64786.1 - 0.038 14.2 0.6 4.2 7.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GBG64786.1 - 0.15 12.4 0.0 0.15 12.4 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain RSRP PF17069.5 GBG64787.1 - 0.042 13.4 6.5 0.046 13.3 6.5 1.0 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Herpes_UL25 PF01499.16 GBG64787.1 - 0.32 9.5 8.4 0.36 9.3 8.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family PA26 PF04636.13 GBG64787.1 - 0.76 8.6 8.1 0.8 8.6 8.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PRTP PF01366.18 GBG64787.1 - 0.94 7.4 5.3 1.1 7.3 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein MAJIN PF15077.6 GBG64787.1 - 1.9 8.2 8.0 2.1 8.1 8.0 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Plasmodium_Vir PF05795.11 GBG64787.1 - 2.2 7.6 7.7 2.4 7.5 7.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Atg14 PF10186.9 GBG64787.1 - 2.2 7.3 9.0 2.2 7.3 9.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 GBG64787.1 - 3.7 6.8 9.2 4.2 6.6 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.10 GBG64787.1 - 6.5 7.0 14.4 8.5 6.7 14.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 V_ATPase_I PF01496.19 GBG64787.1 - 6.9 4.5 7.5 6.9 4.5 7.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_12 PF13087.6 GBG64789.1 - 1e-41 142.8 0.0 6.6e-41 140.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GBG64789.1 - 1.6e-23 83.8 0.0 1.6e-23 83.8 0.0 5.4 4 2 0 4 4 3 1 AAA domain DUF659 PF04937.15 GBG64789.1 - 4.9e-19 68.7 0.0 1.4e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) AAA_19 PF13245.6 GBG64789.1 - 2.6e-08 34.3 0.0 1.6e-07 31.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GBG64789.1 - 3e-08 33.6 0.0 4.6e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 GBG64789.1 - 0.0017 17.7 0.0 0.009 15.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 GBG64789.1 - 0.0076 16.0 0.8 0.086 12.6 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GBG64789.1 - 0.074 13.3 0.0 0.73 10.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain UvrD_C PF13361.6 GBG64789.1 - 0.16 11.4 0.0 0.16 11.4 0.0 2.9 2 1 1 3 3 2 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 GBG64789.1 - 2.1 7.8 0.0 2.1 7.8 0.0 3.9 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain zf-NF-X1 PF01422.17 GBG64789.1 - 2.1 8.5 8.5 12 6.1 8.5 2.4 1 0 0 1 1 1 0 NF-X1 type zinc finger Methyltr_RsmB-F PF01189.17 GBG64790.1 - 3.5e-32 111.7 0.0 9.4e-32 110.3 0.0 1.7 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 GBG64790.1 - 0.0076 16.4 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CDC27 PF09507.10 GBG64790.1 - 0.57 9.5 24.3 0.9 8.9 24.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 GBG64790.1 - 1.6 8.3 17.2 3.3 7.2 17.2 1.5 1 0 0 1 1 1 0 PPP4R2 RVP_2 PF08284.11 GBG64791.1 - 1.4e-05 24.8 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG64791.1 - 5.8e-05 23.6 0.1 0.00015 22.2 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG64791.1 - 0.00014 21.8 3.7 0.00032 20.6 3.7 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG64791.1 - 0.00021 21.9 0.0 0.00055 20.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG64791.1 - 0.0011 18.8 0.1 0.0018 18.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG64791.1 - 0.22 11.4 4.6 0.37 10.7 4.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3807 PF12720.7 GBG64791.1 - 0.6 10.4 13.9 1.5 9.0 12.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Nop14 PF04147.12 GBG64791.1 - 5.7 5.0 21.6 11 4.1 21.6 1.4 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG64791.1 - 5.9 6.1 22.0 13 5.0 22.0 1.5 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG64791.1 - 9.3 5.6 26.4 21 4.4 26.4 1.5 1 0 0 1 1 1 0 SDA1 AAA_12 PF13087.6 GBG64792.1 - 7.7e-44 149.7 0.4 5.8e-43 146.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain RVT_1 PF00078.27 GBG64792.1 - 1.6e-30 106.3 0.1 3.1e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_11 PF13086.6 GBG64792.1 - 1.7e-22 80.5 8.9 4e-21 76.0 0.0 3.8 3 2 0 3 3 3 1 AAA domain AAA_19 PF13245.6 GBG64792.1 - 8.2e-08 32.7 0.1 2.4e-06 27.9 0.0 3.4 3 2 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GBG64792.1 - 2.1e-07 30.9 0.1 0.00015 21.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain gag-asp_proteas PF13975.6 GBG64792.1 - 3.2e-07 30.8 0.0 8.2e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64792.1 - 1.7e-06 28.6 0.0 4.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG64792.1 - 2.9e-06 27.1 0.0 7.8e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64792.1 - 1.4e-05 24.8 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Viral_helicase1 PF01443.18 GBG64792.1 - 0.00056 19.7 0.1 0.018 14.8 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 GBG64792.1 - 0.0088 15.5 2.4 0.047 13.1 0.0 2.6 2 1 0 3 3 3 1 UvrD-like helicase C-terminal domain Retrotrans_gag PF03732.17 GBG64792.1 - 0.038 14.3 1.2 0.16 12.3 0.1 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein AAA PF00004.29 GBG64793.1 - 1.4e-24 87.0 0.0 4.4e-16 59.5 0.0 3.9 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 GBG64793.1 - 5.8e-19 68.0 11.5 1.4e-07 31.5 0.0 4.5 5 0 0 5 5 4 3 AAA lid domain AAA_22 PF13401.6 GBG64793.1 - 0.001 19.4 6.1 0.08 13.2 0.1 4.2 4 1 0 4 4 3 1 AAA domain AAA_5 PF07728.14 GBG64793.1 - 0.0043 17.1 0.0 0.018 15.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG64793.1 - 0.009 15.8 0.0 0.27 11.0 0.0 2.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GBG64793.1 - 0.014 15.5 0.0 0.014 15.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 GBG64793.1 - 0.016 14.6 0.0 0.048 13.0 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GBG64793.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain CRS1_YhbY PF01985.21 GBG64793.1 - 0.14 12.4 1.6 1 9.6 1.6 2.6 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain AAA_28 PF13521.6 GBG64793.1 - 0.19 11.9 0.1 0.19 11.9 0.1 3.0 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 GBG64793.1 - 0.32 11.3 0.0 0.32 11.3 0.0 3.4 3 1 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 GBG64793.1 - 0.44 11.1 13.0 0.19 12.3 0.2 3.3 2 0 0 2 2 2 0 AAA domain DUF1974 PF09317.11 GBG64793.1 - 1.1 8.8 9.2 3 7.3 9.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) AAA_23 PF13476.6 GBG64793.1 - 2.3 8.7 23.9 0.022 15.3 4.3 4.3 4 0 0 4 4 3 0 AAA domain CTNNB1_binding PF08347.11 GBG64793.1 - 2.8 8.1 4.9 8.8 6.5 4.9 1.8 1 0 0 1 1 1 0 N-terminal CTNNB1 binding MFAP1 PF06991.11 GBG64793.1 - 6 6.7 31.0 0.16 11.8 20.1 2.6 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 GBG64794.1 - 0.15 12.2 0.7 0.29 11.3 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 GBG64794.1 - 0.29 9.9 0.3 0.76 8.5 0.3 1.7 1 0 0 1 1 1 0 Presenilin Glyco_transf_34 PF05637.12 GBG64795.1 - 2.9e-26 92.6 0.1 3.4e-25 89.2 0.1 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 GBG64795.1 - 0.025 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Med7 PF05983.11 GBG64796.1 - 1.1e-53 182.2 0.0 1.4e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 MED7 protein DARPP-32 PF05395.12 GBG64796.1 - 0.017 15.3 0.2 0.017 15.3 0.2 1.9 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 cwf18 PF08315.12 GBG64796.1 - 0.52 11.0 5.5 5.8 7.6 1.6 2.5 3 0 0 3 3 3 0 cwf18 pre-mRNA splicing factor Amidohydro_1 PF01979.20 GBG64797.1 - 3.3e-79 266.7 3.7 5.1e-79 266.1 3.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 GBG64797.1 - 2.7e-50 169.8 3.0 4.8e-50 168.9 2.1 1.9 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 GBG64797.1 - 4.6e-40 135.9 0.1 1.2e-38 131.4 0.0 3.0 3 1 0 3 3 3 1 Urease, gamma subunit Urease_beta PF00699.20 GBG64797.1 - 5.8e-40 135.3 0.0 1.2e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 GBG64797.1 - 1.9e-09 37.5 0.5 9.9e-06 25.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family UreD PF01774.17 GBG64798.1 - 8.7e-58 195.7 1.6 3e-56 190.7 0.4 2.1 2 0 0 2 2 2 2 UreD urease accessory protein GCV_T PF01571.21 GBG64798.1 - 0.047 13.0 0.1 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain GNAT_like PF18407.1 GBG64799.1 - 6.4 7.2 11.1 26 5.2 3.5 3.1 1 1 1 2 2 2 0 GCN5-related N-acetyltransferase like domain DUF659 PF04937.15 GBG64800.1 - 2.1e-33 115.3 0.1 3.3e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2201_N PF13203.6 GBG64804.1 - 0.05 13.2 0.0 1.8 8.1 1.3 2.4 1 1 1 2 2 2 0 Putative metallopeptidase domain Histone PF00125.24 GBG64805.1 - 4.9e-22 78.7 2.8 4.9e-22 78.7 2.8 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 IHABP4_N PF16174.5 GBG64806.1 - 0.84 10.2 9.5 2.3 8.8 9.5 1.7 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4746 PF15928.5 GBG64808.1 - 1.1 8.6 7.9 1.7 8.0 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 GBG64808.1 - 2.6 6.2 19.5 3.8 5.6 19.5 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 GBG64808.1 - 3 6.8 16.2 5.2 6.0 16.2 1.3 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.12 GBG64808.1 - 4.4 6.6 20.1 6.6 6.0 20.1 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG64808.1 - 4.6 5.9 7.3 6.2 5.5 7.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF659 PF04937.15 GBG64809.1 - 1.1e-12 48.1 0.0 2.4e-10 40.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64811.1 - 1.7e-06 27.7 0.1 3e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UPF0561 PF10573.9 GBG64811.1 - 0.017 15.2 1.6 1.1 9.4 0.0 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Myb_DNA-bind_4 PF13837.6 GBG64812.1 - 1.7e-08 34.7 0.4 1.7e-08 34.7 0.4 2.8 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG64812.1 - 0.022 14.8 1.7 0.022 14.8 1.7 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG64813.1 - 3.4e-17 62.5 0.0 8.6e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64813.1 - 3.8e-07 29.9 0.0 7.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein HTH_48 PF17906.1 GBG64813.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase DUF2730 PF10805.8 GBG64815.1 - 0.015 15.4 0.2 0.096 12.8 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3580 PF12117.8 GBG64815.1 - 0.054 13.7 0.1 0.085 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) DUF1664 PF07889.12 GBG64815.1 - 6.8 6.8 6.2 0.44 10.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF659 PF04937.15 GBG64816.1 - 5.1e-12 45.9 1.9 5.7e-12 45.8 0.1 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF 659) zf-C2H2_4 PF13894.6 GBG64816.1 - 0.061 14.2 0.6 0.25 12.3 0.6 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger EII-Sor PF03609.14 GBG64816.1 - 0.17 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 PTS system sorbose-specific iic component RT_RNaseH_2 PF17919.1 GBG64817.1 - 2.9e-24 85.0 0.0 6.9e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64817.1 - 9.6e-23 80.5 0.0 3e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64817.1 - 1.8e-18 66.9 0.0 3.2e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG64817.1 - 4.2e-05 24.1 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64817.1 - 5.7e-05 23.6 0.0 0.00015 22.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64817.1 - 0.00038 20.2 0.0 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG64817.1 - 0.0012 19.0 0.0 0.0045 17.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG64817.1 - 0.0097 15.8 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG64817.1 - 0.021 15.1 0.2 0.082 13.2 0.2 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG64817.1 - 0.024 14.4 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease BLOC1_2 PF10046.9 GBG64818.1 - 0.17 12.2 4.4 0.33 11.3 1.2 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SPARC_Ca_bdg PF10591.9 GBG64818.1 - 5.9 7.3 6.5 0.95 9.8 1.4 2.3 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region HIP1_clath_bdg PF16515.5 GBG64818.1 - 9.6 6.9 16.8 0.077 13.6 4.0 3.0 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RT_RNaseH PF17917.1 GBG64819.1 - 1.8e-45 153.5 0.0 5.4e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64819.1 - 1.9e-35 120.9 0.0 9.8e-21 73.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64819.1 - 2.8e-15 56.2 0.0 2.8e-15 56.2 0.0 2.1 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG64819.1 - 0.00043 20.4 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG64819.1 - 0.037 14.2 0.0 2 8.6 0.0 3.0 1 1 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG64820.1 - 0.071 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG64821.1 - 3.9e-25 87.8 0.0 8.7e-25 86.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64821.1 - 1.9e-20 73.1 0.0 1.2e-19 70.5 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64821.1 - 3.8e-18 65.8 0.0 7.3e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG64821.1 - 0.022 14.6 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease TMEM247 PF15444.6 GBG64821.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 CCSAP PF15748.5 GBG64821.1 - 3.8 7.6 10.5 0.46 10.6 2.3 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated zf-CCHC PF00098.23 GBG64822.1 - 0.01 15.9 1.7 0.01 15.9 1.7 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG64822.1 - 0.019 14.7 0.2 0.035 13.8 0.2 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF3915 PF13054.6 GBG64822.1 - 1.9 8.5 7.2 4.6 7.2 7.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Asp_protease_2 PF13650.6 GBG64824.1 - 0.002 18.8 0.0 0.0038 17.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64824.1 - 0.0044 17.6 0.0 0.0078 16.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease CDC45 PF02724.14 GBG64824.1 - 0.0058 15.0 4.7 0.0075 14.6 4.7 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF4366 PF14283.6 GBG64824.1 - 0.38 10.8 1.4 0.61 10.1 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 GBG64824.1 - 1 8.0 5.0 1.4 7.6 5.0 1.1 1 0 0 1 1 1 0 Presenilin Topo_Zn_Ribbon PF08272.11 GBG64825.1 - 0.069 12.8 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like WD40_alt PF14077.6 GBG64826.1 - 0.082 12.8 5.4 0.13 12.1 0.2 3.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif zf-MYND PF01753.18 GBG64829.1 - 1.9e-07 31.0 17.0 1.9e-07 31.0 17.0 2.7 2 0 0 2 2 2 1 MYND finger Sel1 PF08238.12 GBG64829.1 - 0.002 18.8 9.5 0.57 11.0 0.0 4.5 4 1 0 4 4 4 2 Sel1 repeat DUF659 PF04937.15 GBG64830.1 - 3.6e-14 52.9 0.0 6.2e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) TrkH PF02386.16 GBG64831.1 - 4.5e-59 200.2 15.4 1.6e-53 181.9 15.1 3.7 2 1 0 2 2 2 2 Cation transport protein Protocadherin PF08374.11 GBG64831.1 - 0.0016 18.4 0.2 0.0033 17.5 0.2 1.4 1 0 0 1 1 1 1 Protocadherin CLN3 PF02487.17 GBG64831.1 - 0.011 14.8 1.0 0.022 13.8 1.0 1.4 1 0 0 1 1 1 0 CLN3 protein Coilin_N PF15862.5 GBG64831.1 - 0.018 14.8 2.3 0.031 14.1 2.3 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF2306 PF10067.9 GBG64831.1 - 0.025 14.8 6.1 0.25 11.5 0.8 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) Spt20 PF12090.8 GBG64831.1 - 0.045 13.4 21.5 0.083 12.5 21.5 1.3 1 0 0 1 1 1 0 Spt20 family MID_MedPIWI PF18296.1 GBG64831.1 - 0.11 12.3 2.8 0.17 11.6 2.8 1.2 1 0 0 1 1 1 0 MID domain of medPIWI FHIPEP PF00771.20 GBG64831.1 - 0.13 10.7 0.5 0.2 10.1 0.5 1.1 1 0 0 1 1 1 0 FHIPEP family Borrelia_P83 PF05262.11 GBG64831.1 - 0.25 9.8 5.0 0.36 9.3 5.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Bac_export_2 PF01312.19 GBG64831.1 - 2.5 7.2 5.6 0.26 10.5 0.5 1.8 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family SpoIIP PF07454.11 GBG64831.1 - 4.6 6.6 9.5 7.7 5.9 9.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 GBG64831.1 - 5.1 6.8 6.2 8.7 6.0 5.2 1.8 2 0 0 2 2 2 0 Connexin RR_TM4-6 PF06459.12 GBG64831.1 - 7 6.4 10.8 11 5.7 10.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 GBG64831.1 - 7.2 5.9 20.1 11 5.3 20.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4834 PF16118.5 GBG64831.1 - 7.9 7.5 11.4 0.13 13.2 3.8 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) Myb_DNA-bind_4 PF13837.6 GBG64832.1 - 7.1e-05 23.1 1.0 0.00017 21.9 1.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CENP-B_dimeris PF09026.10 GBG64835.1 - 0.0044 17.4 0.9 0.0081 16.5 0.9 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF3682 PF12446.8 GBG64835.1 - 0.043 14.3 2.1 0.071 13.6 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PBP1_TM PF14812.6 GBG64835.1 - 0.14 12.5 3.4 0.3 11.5 3.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4813 PF16072.5 GBG64836.1 - 1.2 8.8 9.2 1.7 8.3 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Nfu_N PF08712.11 GBG64837.1 - 4.8e-32 109.9 0.0 1.1e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 GBG64837.1 - 1.6e-26 92.2 0.1 2.5e-26 91.6 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain ZapB PF06005.12 GBG64838.1 - 0.0081 16.6 20.2 0.022 15.2 0.1 3.7 3 1 0 3 3 3 2 Cell division protein ZapB HALZ PF02183.18 GBG64838.1 - 0.012 15.9 11.8 0.38 11.0 3.8 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper S-antigen PF05756.11 GBG64838.1 - 0.029 14.7 0.3 0.072 13.5 0.3 1.7 1 0 0 1 1 1 0 S-antigen protein DivIC PF04977.15 GBG64838.1 - 0.22 11.3 12.4 0.77 9.6 2.0 3.4 2 1 1 3 3 3 0 Septum formation initiator AATF-Che1 PF13339.6 GBG64838.1 - 1.1 10.0 8.4 4.2 8.0 8.4 2.2 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor MTBP_C PF14920.6 GBG64838.1 - 6 6.5 13.1 4.6 6.9 11.1 1.7 1 1 1 2 2 2 0 MDM2-binding KLRAQ PF10205.9 GBG64838.1 - 6.3 7.1 15.4 1.6 9.0 6.2 3.5 2 2 1 3 3 3 0 Predicted coiled-coil domain-containing protein DUF836 PF05768.14 GBG64839.1 - 1e-17 64.3 0.0 1.8e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) ABC1 PF03109.16 GBG64840.1 - 3.6e-35 120.7 0.9 7.3e-35 119.7 0.9 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GBG64840.1 - 4e-05 23.7 0.0 0.0001 22.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 GBG64840.1 - 0.0048 16.5 0.1 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 RIO1 family WaaY PF06176.11 GBG64840.1 - 0.022 14.4 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) His_Phos_1 PF00300.22 GBG64841.1 - 1.4e-18 67.3 0.6 3.1e-11 43.3 0.0 3.0 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Ribosomal_L30_N PF08079.12 GBG64842.1 - 1.8e-23 82.6 7.9 3.3e-23 81.7 7.9 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 GBG64842.1 - 8.3e-14 51.2 3.4 8.3e-14 51.2 3.4 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Mpp10 PF04006.12 GBG64843.1 - 0.00089 17.8 40.3 0.001 17.6 40.3 1.0 1 0 0 1 1 1 1 Mpp10 protein Nop53 PF07767.11 GBG64843.1 - 0.0095 15.4 44.9 0.011 15.1 44.9 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GBG64843.1 - 0.011 14.1 37.0 0.012 13.9 37.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3807 PF12720.7 GBG64843.1 - 0.035 14.4 40.0 0.041 14.1 40.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) YL1 PF05764.13 GBG64843.1 - 0.093 12.8 45.4 0.12 12.5 45.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein YqfQ PF14181.6 GBG64843.1 - 0.1 12.8 29.7 0.15 12.2 29.7 1.4 1 0 0 1 1 1 0 YqfQ-like protein SRP-alpha_N PF04086.13 GBG64843.1 - 0.25 11.2 30.0 0.29 11.0 30.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Nop14 PF04147.12 GBG64843.1 - 0.45 8.7 40.7 0.54 8.4 40.7 1.0 1 0 0 1 1 1 0 Nop14-like family TIMELESS_C PF05029.13 GBG64843.1 - 0.61 9.2 38.1 0.7 9.0 38.1 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region PAT1 PF09770.9 GBG64843.1 - 0.64 8.2 21.0 0.66 8.2 21.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LTV PF04180.14 GBG64843.1 - 0.68 9.6 30.7 0.78 9.4 30.7 1.1 1 0 0 1 1 1 0 Low temperature viability protein RR_TM4-6 PF06459.12 GBG64843.1 - 0.82 9.4 43.3 0.93 9.3 43.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Membralin PF09746.9 GBG64843.1 - 0.94 8.4 19.0 1 8.3 19.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 GBG64843.1 - 1.2 7.8 31.6 1.4 7.6 31.6 1.0 1 0 0 1 1 1 0 Presenilin TCP PF03634.13 GBG64843.1 - 1.2 9.6 27.9 1.8 9.1 27.9 1.3 1 0 0 1 1 1 0 TCP family transcription factor CCSAP PF15748.5 GBG64843.1 - 1.3 9.1 37.1 1.5 8.9 37.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated eIF-3c_N PF05470.12 GBG64843.1 - 1.5 7.1 26.6 1.6 6.9 26.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Endostatin PF06482.11 GBG64843.1 - 1.8 8.0 16.9 2.2 7.7 16.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4746 PF15928.5 GBG64843.1 - 2.3 7.6 38.0 2.8 7.3 38.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC27 PF09507.10 GBG64843.1 - 3.1 7.1 47.5 4.1 6.7 47.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vfa1 PF08432.10 GBG64843.1 - 3.5 7.9 46.0 5.3 7.3 46.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4604 PF15377.6 GBG64843.1 - 4.1 7.8 50.3 7.3 7.0 50.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SLC12 PF03522.15 GBG64843.1 - 4.3 6.3 31.1 4.9 6.1 31.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 GBG64843.1 - 4.4 5.7 22.9 4.9 5.5 22.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Spt20 PF12090.8 GBG64843.1 - 4.6 6.8 29.8 8.1 6.0 29.8 1.4 1 0 0 1 1 1 0 Spt20 family Hid1 PF12722.7 GBG64843.1 - 5.3 5.1 26.0 5.9 4.9 26.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.12 GBG64843.1 - 5.7 7.1 32.4 6.4 7.0 32.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SpoIIIAH PF12685.7 GBG64843.1 - 6.5 6.5 30.9 7.9 6.2 30.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein AF-4 PF05110.13 GBG64843.1 - 6.5 4.7 36.9 7.9 4.4 36.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CobT PF06213.12 GBG64843.1 - 7 6.0 41.4 9.7 5.5 41.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4045 PF13254.6 GBG64843.1 - 8.8 5.9 32.8 10 5.6 32.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) ALMT PF11744.8 GBG64843.1 - 8.9 5.0 26.0 12 4.6 26.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter LAP1C PF05609.12 GBG64843.1 - 9.2 5.2 25.4 11 5.0 25.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC73_C PF05179.14 GBG64844.1 - 1.1e-44 151.9 0.0 1.5e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 GBG64844.1 - 0.0088 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal RT_RNaseH_2 PF17919.1 GBG64846.1 - 4.4e-24 84.4 0.0 8e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64846.1 - 1.1e-20 73.9 0.0 2.4e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ACT_3 PF10000.9 GBG64846.1 - 0.082 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 ACT domain RVT_1 PF00078.27 GBG64847.1 - 9.6e-27 93.9 0.0 1.7e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64847.1 - 8.8e-14 51.4 2.7 1.1e-13 51.0 0.1 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG64847.1 - 7.2e-13 48.8 0.0 2.3e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG64847.1 - 9e-05 22.6 0.0 0.00036 20.7 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG64847.1 - 0.045 13.5 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Integrase core domain Myb_DNA-bind_4 PF13837.6 GBG64848.1 - 2.6e-08 34.1 1.3 4.7e-08 33.3 1.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4378 PF14309.6 GBG64849.1 - 9.7e-31 107.4 0.0 1.4e-29 103.6 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4378) Pkinase PF00069.25 GBG64851.1 - 2.5e-46 158.2 0.0 3.5e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG64851.1 - 5e-43 147.2 0.0 7.6e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 GBG64851.1 - 5.4e-05 22.9 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Kinase-like PF14531.6 GBG64851.1 - 0.0013 18.1 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PRIMA1 PF16101.5 GBG64851.1 - 0.064 13.3 0.3 0.15 12.1 0.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AP1AR PF15745.5 GBG64852.1 - 1.1 8.9 16.4 1.7 8.2 16.4 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF572 PF04502.13 GBG64852.1 - 1.8 8.1 18.4 2.4 7.7 18.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pro_isomerase PF00160.21 GBG64853.1 - 2.6e-49 167.5 0.1 3e-49 167.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPRY PF00622.28 GBG64853.1 - 0.046 13.8 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 SPRY domain SPC25 PF06703.11 GBG64854.1 - 1.2e-17 64.2 0.1 1.5e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Mob1_phocein PF03637.17 GBG64854.1 - 0.058 13.4 0.0 0.069 13.2 0.0 1.1 1 0 0 1 1 1 0 Mob1/phocein family Cupin_1 PF00190.22 GBG64855.1 - 2.5e-48 163.5 0.1 3.7e-31 107.8 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GBG64855.1 - 5.3e-07 29.2 0.2 0.00088 18.9 0.0 2.8 2 0 0 2 2 2 2 Cupin domain CENP-C_C PF11699.8 GBG64855.1 - 0.0018 18.4 0.2 0.023 14.9 0.1 2.3 2 0 0 2 2 2 1 Mif2/CENP-C like IGPD PF00475.18 GBG64856.1 - 7.1e-64 214.5 2.6 9.1e-64 214.1 1.9 1.5 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase MAM33 PF02330.16 GBG64856.1 - 0.0048 16.9 2.9 0.022 14.7 1.8 2.0 2 0 0 2 2 2 1 Mitochondrial glycoprotein Roughex PF06020.11 GBG64856.1 - 0.039 13.0 1.4 0.066 12.3 1.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Pox_Ag35 PF03286.14 GBG64856.1 - 0.5 10.1 5.8 0.27 11.0 1.1 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Myc_N PF01056.18 GBG64856.1 - 0.72 9.7 7.1 4.3 7.1 2.1 2.2 2 0 0 2 2 2 0 Myc amino-terminal region GEN1_C PF18380.1 GBG64856.1 - 2.1 9.3 6.1 11 7.0 2.1 2.8 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain RVT_1 PF00078.27 GBG64857.1 - 1.3e-08 34.7 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG64857.1 - 0.00012 22.6 0.4 0.00042 20.8 0.1 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64857.1 - 0.00016 22.2 0.0 0.00058 20.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 GBG64857.1 - 0.0012 18.9 1.0 0.0026 17.8 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG64857.1 - 0.053 13.8 0.0 3 8.2 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG64857.1 - 0.21 11.4 0.6 1.2 8.9 0.3 2.2 2 0 0 2 2 2 0 Aspartyl protease FOXP-CC PF16159.5 GBG64857.1 - 2.1 9.0 4.5 1.2 9.9 1.0 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain SDA1 PF05285.12 GBG64858.1 - 9.5e-06 25.3 28.4 9.5e-06 25.3 28.4 3.2 3 0 0 3 3 3 2 SDA1 CDC45 PF02724.14 GBG64858.1 - 0.001 17.5 23.6 0.001 17.5 23.6 3.2 2 1 0 3 3 3 1 CDC45-like protein TFIIA PF03153.13 GBG64858.1 - 0.0012 19.0 25.6 0.0012 19.0 25.6 3.0 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 GBG64858.1 - 0.0064 14.8 67.2 0.0057 14.9 35.7 2.9 3 0 0 3 3 3 2 Nop14-like family PseudoU_synth_2 PF00849.22 GBG64859.1 - 2.4e-24 86.3 0.0 6.1e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 RNA pseudouridylate synthase Co_AT_N PF12557.8 GBG64859.1 - 0.079 12.9 0.5 0.19 11.7 0.5 1.7 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal DLEU7 PF15760.5 GBG64859.1 - 0.26 10.8 4.7 2.5 7.5 0.4 2.7 3 0 0 3 3 3 0 Leukemia-associated protein 7 Integrase_H2C2 PF17921.1 GBG64861.1 - 2.6e-15 56.3 0.1 7.1e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64861.1 - 1.6e-07 31.5 0.0 3.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG64861.1 - 2.1e-06 28.0 0.1 4.7e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64861.1 - 0.0013 18.7 0.1 0.0034 17.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG64861.1 - 0.0031 17.7 0.0 0.008 16.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG64861.1 - 0.27 11.4 0.7 0.57 10.4 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF913 PF06025.12 GBG64861.1 - 5.5 5.9 4.4 11 4.9 4.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) gag-asp_proteas PF13975.6 GBG64862.1 - 4.9e-06 27.0 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64862.1 - 0.00058 20.4 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG64862.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64862.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG64862.1 - 0.22 11.2 1.9 0.27 10.9 0.3 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like CDC45 PF02724.14 GBG64863.1 - 0.19 10.0 10.8 0.28 9.4 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG64863.1 - 0.43 10.0 15.0 0.76 9.1 15.0 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG64863.1 - 0.56 8.4 18.5 0.17 10.1 15.9 1.4 2 0 0 2 2 2 0 Nop14-like family DNA_pol_phi PF04931.13 GBG64863.1 - 2.1 6.4 25.2 1.2 7.1 23.0 1.6 2 0 0 2 2 2 0 DNA polymerase phi DUF659 PF04937.15 GBG64865.1 - 2.1e-07 30.9 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Peptidase_U32 PF01136.19 GBG64870.1 - 0.021 13.9 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Peptidase family U32 cwf21 PF08312.12 GBG64870.1 - 0.031 14.4 0.6 0.076 13.2 0.6 1.6 1 0 0 1 1 1 0 cwf21 domain Nbl1_Borealin_N PF10444.9 GBG64870.1 - 0.69 9.6 3.2 0.79 9.4 0.8 2.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal HSP70 PF00012.20 GBG64873.1 - 4.1e-260 864.1 1.9 4.7e-260 863.9 1.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG64873.1 - 2.2e-12 46.5 0.3 7.1e-10 38.2 0.1 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG64873.1 - 1.2e-06 28.4 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG64873.1 - 0.0022 18.4 0.8 2.7 8.5 0.0 3.2 3 0 0 3 3 3 2 Cell division protein FtsA FecCD PF01032.18 GBG64874.1 - 0.015 14.3 0.5 0.021 13.9 0.5 1.2 1 0 0 1 1 1 0 FecCD transport family RT_RNaseH_2 PF17919.1 GBG64875.1 - 2.5e-35 120.5 0.0 3.8e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64875.1 - 1.2e-30 105.9 0.0 2.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64875.1 - 1.6e-08 34.3 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Homeodomain PF00046.29 GBG64878.1 - 0.011 15.5 0.0 0.04 13.8 0.0 2.0 1 0 0 1 1 1 0 Homeodomain RT_RNaseH_2 PF17919.1 GBG64879.1 - 4e-17 62.1 0.0 1.9e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64879.1 - 2.1e-15 56.9 0.0 2.9e-14 53.2 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64879.1 - 3.8e-10 39.7 0.0 6.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG64879.1 - 0.0002 21.8 0.6 0.00085 19.8 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64879.1 - 0.0095 16.6 0.3 0.058 14.1 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Ribosomal_S17_N PF16205.5 GBG64879.1 - 0.012 16.0 0.0 0.05 14.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal_S17 N-terminal Lamprin PF06403.11 GBG64879.1 - 0.45 10.5 11.9 1.1 9.2 11.9 1.6 1 0 0 1 1 1 0 Lamprin ArfGap PF01412.18 GBG64880.1 - 9.3e-34 116.0 0.2 2.3e-33 114.8 0.2 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf EspF PF04806.12 GBG64880.1 - 0.11 12.9 0.3 0.11 12.9 0.3 2.9 3 0 0 3 3 3 0 EspF protein repeat RT_RNaseH_2 PF17919.1 GBG64883.1 - 6.4e-29 99.9 0.0 1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64883.1 - 2.7e-22 79.0 0.0 4.5e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64883.1 - 1.2e-13 51.1 0.1 1.6e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG64883.1 - 2.8 7.3 22.2 4 6.8 22.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG64883.1 - 4 6.7 19.4 5.4 6.2 19.4 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG64883.1 - 8.8 4.5 13.3 13 3.9 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG64884.1 - 0.67 8.1 18.8 0.74 8.0 18.8 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG64884.1 - 0.95 8.8 22.4 1.2 8.5 22.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG64884.1 - 1.5 8.1 19.9 1.8 7.8 19.9 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG64884.1 - 2.7 6.2 13.4 3.7 5.7 13.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG64884.1 - 6.3 6.3 9.0 8.3 5.9 9.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Glyco_transf_29 PF00777.18 GBG64885.1 - 1.1e-07 31.6 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Phage_integrase PF00589.22 GBG64886.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.7 1 1 0 1 1 1 0 Phage integrase family TPR_1 PF00515.28 GBG64887.1 - 1.3e-21 75.4 3.3 1.1e-06 28.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.6 GBG64887.1 - 8.3e-21 74.3 0.0 2.5e-20 72.8 0.0 1.9 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 GBG64887.1 - 2.1e-16 58.6 2.8 0.00034 20.5 1.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG64887.1 - 1.4e-09 37.4 3.9 0.0066 16.6 0.8 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG64887.1 - 8.9e-09 34.9 0.3 8e-05 22.2 0.0 3.3 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 GBG64887.1 - 7.4e-05 23.3 0.0 7.4e-05 23.3 0.0 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG64887.1 - 0.0012 19.1 1.3 0.0034 17.6 0.7 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 GBG64887.1 - 0.0031 17.4 2.3 0.29 11.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG64887.1 - 0.012 15.5 3.1 0.25 11.3 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Adeno_VII PF03228.14 GBG64887.1 - 0.021 15.5 0.2 0.082 13.6 0.2 2.1 1 0 0 1 1 1 0 Adenoviral core protein VII TPR_9 PF13371.6 GBG64887.1 - 0.025 14.7 0.5 4.2 7.6 0.2 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GBG64887.1 - 0.13 12.4 1.0 6.1 7.0 0.1 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 GBG64887.1 - 1.3 10.1 0.0 1.3 10.1 0.0 4.2 2 1 2 4 4 3 0 Tetratricopeptide repeat DUF659 PF04937.15 GBG64888.1 - 4.2e-33 114.4 0.4 6.9e-33 113.7 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) HEAT_2 PF13646.6 GBG64888.1 - 0.033 14.6 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats DUF503 PF04456.12 GBG64888.1 - 0.3 11.0 1.4 0.76 9.7 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF503) RVT_1 PF00078.27 GBG64889.1 - 4e-30 105.0 0.0 7.6e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64889.1 - 1.8e-15 56.8 0.1 5.7e-15 55.2 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64889.1 - 3.1e-12 46.7 0.0 7.5e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Alpha-amyl_C2 PF07821.12 GBG64889.1 - 3.8e-06 27.0 0.0 7.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain zf-H2C2 PF09337.10 GBG64889.1 - 0.0052 17.0 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG64890.1 - 4e-30 105.0 0.0 7.6e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG64890.1 - 1.8e-15 56.8 0.1 5.7e-15 55.2 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64890.1 - 3.1e-12 46.7 0.0 7.5e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Alpha-amyl_C2 PF07821.12 GBG64890.1 - 3.8e-06 27.0 0.0 7.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain zf-H2C2 PF09337.10 GBG64890.1 - 0.0052 17.0 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Acetyltransf_1 PF00583.25 GBG64891.1 - 1e-15 58.0 0.0 1.6e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GBG64891.1 - 2.4e-10 40.4 0.0 3.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GBG64891.1 - 2e-09 37.7 0.0 3.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG64891.1 - 2.5e-09 37.0 0.1 4.4e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GBG64891.1 - 2.2e-05 25.2 0.0 3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GBG64891.1 - 0.0026 17.4 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GBG64891.1 - 0.0033 17.5 0.0 0.0072 16.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GBG64891.1 - 0.012 15.8 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GBG64891.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FAP PF07174.11 GBG64891.1 - 8.3 5.8 9.7 3.2 7.1 7.4 1.4 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Retrotrans_gag PF03732.17 GBG64895.1 - 0.0036 17.6 3.5 0.0057 16.9 0.1 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein UPF0242 PF06785.11 GBG64895.1 - 0.64 10.1 3.6 1.1 9.3 3.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus E1-E2_ATPase PF00122.20 GBG64896.1 - 1.1 8.8 4.9 1.5 8.3 4.9 1.2 1 0 0 1 1 1 0 E1-E2 ATPase O-FucT PF10250.9 GBG64898.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.7 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Spore_III_AF PF09581.10 GBG64899.1 - 0.002 18.2 1.8 0.002 18.2 1.8 2.6 2 1 0 2 2 2 1 Stage III sporulation protein AF (Spore_III_AF) LMBR1 PF04791.16 GBG64899.1 - 0.0053 15.7 6.6 0.0083 15.1 6.6 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein EDS1_EP PF18117.1 GBG64899.1 - 0.27 11.7 10.1 0.12 12.8 5.7 2.4 2 0 0 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain PEP-utilisers_N PF05524.13 GBG64899.1 - 0.7 10.1 17.2 0.11 12.7 5.6 2.6 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DNA_pack_N PF02500.15 GBG64899.1 - 1.3 8.7 5.5 2.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus AAA_23 PF13476.6 GBG64899.1 - 2.5 8.6 27.4 4.5 7.7 13.6 2.4 2 0 0 2 2 2 0 AAA domain DUF5069 PF16798.5 GBG64899.1 - 2.8 8.2 9.5 0.32 11.2 0.2 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF5069) RVT_1 PF00078.27 GBG64900.1 - 2.3e-28 99.2 0.1 3.7e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64900.1 - 2.3e-25 88.5 0.0 1.1e-24 86.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64900.1 - 8.4e-23 80.7 0.0 1.7e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64900.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease O-FucT PF10250.9 GBG64901.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Rhomboid_SP PF12595.8 GBG64902.1 - 2.6 7.4 7.5 0.52 9.6 0.4 2.3 1 1 1 2 2 2 0 Rhomboid serine protease DUF16 PF01519.16 GBG64903.1 - 0.038 14.5 4.6 0.076 13.5 3.8 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1319 PF07028.11 GBG64904.1 - 0.059 13.6 1.2 3.8 7.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) HALZ PF02183.18 GBG64904.1 - 0.35 11.1 8.8 0.053 13.8 1.2 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper Cytochrom_NNT PF03264.14 GBG64904.1 - 1.4 8.6 20.3 1.9 8.2 5.7 2.6 1 1 1 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region TSC22 PF01166.18 GBG64904.1 - 1.6 9.1 5.0 2 8.8 1.2 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Cytochrome_C7 PF14522.6 GBG64904.1 - 2.3 8.3 22.9 2.8e+03 -1.6 22.9 3.0 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c RVT_1 PF00078.27 GBG64905.1 - 4.3e-26 91.8 0.0 7.5e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64905.1 - 1.7e-25 89.0 0.0 4e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64905.1 - 8.9e-24 83.8 0.0 2.3e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64905.1 - 1.2e-18 67.0 0.3 3.2e-18 65.6 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG64905.1 - 1.8e-05 25.2 0.0 6.5e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64905.1 - 0.00012 22.5 0.0 0.00027 21.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG64905.1 - 0.00014 21.6 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64905.1 - 0.00052 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG64905.1 - 0.019 15.2 0.0 0.088 13.1 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG64906.1 - 5.5e-37 127.4 0.1 8e-37 126.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG64906.1 - 1.7e-15 56.8 0.0 6.1e-15 55.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG64906.1 - 2.4e-07 30.6 0.0 6.8e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG64906.1 - 1.4e-06 28.5 0.0 3.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG64906.1 - 4e-06 27.4 0.0 8.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG64906.1 - 0.00028 21.4 0.0 0.0009 19.8 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG64906.1 - 0.0021 17.8 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG64906.1 - 0.0096 15.7 0.0 0.031 14.1 0.0 1.8 1 1 0 1 1 1 1 Aspartyl protease PIG-F PF06699.11 GBG64907.1 - 0.00021 21.5 0.1 0.00026 21.2 0.1 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F LapA_dom PF06305.11 GBG64907.1 - 0.26 11.1 0.2 0.26 11.1 0.2 2.1 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain bZIP_1 PF00170.21 GBG64908.1 - 0.08 13.0 2.5 0.23 11.6 2.5 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF2385 PF09539.10 GBG64908.1 - 0.11 13.0 0.5 5.1 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) Jnk-SapK_ap_N PF09744.9 GBG64908.1 - 0.11 12.7 2.9 1.1 9.5 1.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Tropomyosin PF00261.20 GBG64908.1 - 0.12 11.7 4.7 0.22 10.9 4.7 1.4 1 0 0 1 1 1 0 Tropomyosin ABC_tran_CTD PF16326.5 GBG64908.1 - 0.61 10.4 3.9 0.45 10.8 0.3 2.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain zf-CCHC_2 PF13696.6 GBG64908.1 - 0.85 9.5 2.1 1.3 8.9 2.1 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF3067 PF11267.8 GBG64909.1 - 5.2e-30 103.9 0.0 7.1e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) DUF674 PF05056.12 GBG64910.1 - 2.4e-13 49.8 0.9 1e-12 47.7 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF674) Rieske PF00355.26 GBG64910.1 - 0.051 13.5 0.1 0.051 13.5 0.1 2.2 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain NYD-SP28_assoc PF14775.6 GBG64911.1 - 3.6e-06 27.0 0.5 3.6e-06 27.0 0.5 1.7 2 0 0 2 2 2 1 Sperm tail C-terminal domain PROCN PF08083.11 GBG64912.1 - 1.6e-237 787.9 6.2 2.6e-237 787.2 6.2 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 GBG64912.1 - 3.8e-130 432.4 0.7 6.3e-130 431.7 0.7 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 GBG64912.1 - 1.1e-90 301.7 4.4 1.1e-89 298.5 2.5 2.6 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 GBG64912.1 - 2.5e-87 290.5 4.8 4.3e-87 289.7 3.8 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 GBG64912.1 - 6.8e-73 243.1 0.0 1.3e-72 242.2 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 GBG64912.1 - 5.9e-53 178.0 1.0 9.8e-52 174.1 0.0 2.6 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.9 GBG64912.1 - 7.7e-47 157.6 0.2 2.4e-46 156.0 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 GBG64912.1 - 3.4e-09 36.7 0.0 1.5e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF659 PF04937.15 GBG64913.1 - 1.4e-21 77.0 0.0 2.2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64913.1 - 6.3e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region GTP_EFTU PF00009.27 GBG64914.1 - 6.3e-49 166.2 0.0 1e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GBG64914.1 - 2.9e-19 68.9 0.0 5.9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 GBG64914.1 - 3.6e-07 30.3 0.6 7.8e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 GBG64914.1 - 9.1e-06 26.0 11.8 2e-05 24.9 8.9 2.8 2 1 0 2 2 2 1 Elongation factor Tu domain 2 Septin PF00735.18 GBG64914.1 - 0.061 12.6 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 GBG64914.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_II PF14492.6 GBG64914.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Elongation Factor G, domain II Nop14 PF04147.12 GBG64915.1 - 0.041 12.1 5.8 0.05 11.8 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG64915.1 - 0.41 10.0 8.0 0.52 9.7 8.0 1.1 1 0 0 1 1 1 0 SDA1 PsbI PF02532.14 GBG64915.1 - 0.44 10.5 1.1 0.82 9.7 1.1 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) CDC45 PF02724.14 GBG64915.1 - 0.56 8.4 6.2 0.71 8.1 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG64916.1 - 0.0021 16.4 37.8 0.0021 16.4 37.8 2.1 2 0 0 2 2 2 1 Nop14-like family DUF4799 PF16056.5 GBG64916.1 - 0.0072 15.5 3.5 0.0072 15.5 3.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4799) Spore_coat_CotO PF14153.6 GBG64916.1 - 7.1 6.5 30.7 0.29 11.0 21.5 2.3 2 0 0 2 2 2 0 Spore coat protein CotO CHAT PF12770.7 GBG64917.1 - 3.9e-43 147.9 0.0 5e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 CHAT domain TPR_8 PF13181.6 GBG64917.1 - 0.046 14.0 0.9 7.3 7.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG64917.1 - 0.05 13.7 0.2 18 5.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ADIP PF11559.8 GBG64918.1 - 0.005 16.9 1.8 0.0092 16.1 1.8 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ZapB PF06005.12 GBG64918.1 - 0.0077 16.6 1.7 0.026 14.9 1.1 2.1 2 0 0 2 2 2 1 Cell division protein ZapB Spc7 PF08317.11 GBG64918.1 - 0.011 14.6 0.3 0.019 13.8 0.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Filament PF00038.21 GBG64918.1 - 0.018 14.6 0.2 0.035 13.7 0.2 1.4 1 0 0 1 1 1 0 Intermediate filament protein DUF745 PF05335.13 GBG64918.1 - 0.035 13.8 0.9 0.056 13.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ATP-synt_B PF00430.18 GBG64918.1 - 0.054 13.6 3.4 0.11 12.6 3.4 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) NEMO PF11577.8 GBG64918.1 - 0.054 13.5 0.4 0.11 12.5 0.4 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO TPR_MLP1_2 PF07926.12 GBG64918.1 - 0.1 12.7 4.5 0.06 13.4 2.2 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 GBG64918.1 - 0.15 11.4 3.2 0.21 10.9 1.5 2.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Myb_DNA-bind_4 PF13837.6 GBG64919.1 - 4.2e-08 33.4 0.6 7.1e-08 32.7 0.6 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 GBG64919.1 - 0.14 13.2 0.3 0.27 12.2 0.3 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Fez1 PF06818.15 GBG64920.1 - 0.29 11.6 5.5 0.47 10.9 5.5 1.2 1 0 0 1 1 1 0 Fez1 RT_RNaseH PF17917.1 GBG64921.1 - 1.4e-19 70.3 0.0 2.5e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG64921.1 - 2e-19 69.5 0.0 3.9e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64921.1 - 2.9e-14 52.9 0.3 6e-14 51.9 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG64921.1 - 1.8e-08 34.1 0.0 3.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG64921.1 - 0.026 14.8 0.9 0.049 13.9 0.9 1.5 1 0 0 1 1 1 0 H2C2 zinc finger SIP1 PF04938.12 GBG64922.1 - 1.3e-69 234.3 0.0 1.9e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) TPT PF03151.16 GBG64923.1 - 1.5e-40 139.4 18.9 1.6e-40 139.3 18.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GBG64923.1 - 1.8e-14 53.7 18.5 2.4e-14 53.3 18.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GBG64923.1 - 8.3e-09 35.7 28.0 0.00022 21.4 12.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family NopRA1 PF16201.5 GBG64924.1 - 6.2e-47 159.8 1.5 1.7e-46 158.4 1.5 1.8 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 GBG64924.1 - 2.1e-46 158.9 0.0 7.9e-44 150.4 0.0 3.3 3 0 0 3 3 3 2 Ribosome 60S biogenesis N-terminal Cys_Met_Meta_PP PF01053.20 GBG64926.1 - 8.4e-101 337.3 0.0 1.1e-65 221.7 0.1 2.1 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GBG64926.1 - 2.4e-05 23.7 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GBG64926.1 - 0.00018 20.6 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GBG64926.1 - 0.00048 19.5 0.1 0.00069 19.0 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 GBG64926.1 - 0.032 13.1 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein ZnuA PF01297.17 GBG64926.1 - 0.062 12.7 0.0 0.13 11.7 0.0 1.4 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Methyltr_RsmB-F PF01189.17 GBG64926.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Pkinase PF00069.25 GBG64927.1 - 5.5e-49 166.9 0.0 1.1e-48 165.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG64927.1 - 1.8e-44 152.0 0.0 2.6e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG64927.1 - 0.041 12.7 0.0 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 GBG64927.1 - 0.063 13.2 0.2 0.24 11.3 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family SKG6 PF08693.10 GBG64927.1 - 0.22 11.0 3.5 0.48 9.9 3.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain gag-asp_proteas PF13975.6 GBG64928.1 - 0.0006 20.3 0.1 0.0022 18.5 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG64928.1 - 0.0027 18.3 0.1 0.012 16.2 0.1 2.1 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG64928.1 - 0.016 15.5 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG64928.1 - 0.027 14.7 1.2 0.13 12.6 0.1 2.5 2 1 1 3 3 3 0 Retrotransposon gag protein RETICULATA-like PF11891.8 GBG64929.1 - 4.2e-65 218.9 0.1 1.4e-64 217.2 0.0 1.7 2 0 0 2 2 2 1 Protein RETICULATA-related DUF4689 PF15755.5 GBG64929.1 - 0.035 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) zf-CCHC PF00098.23 GBG64930.1 - 2.4e-05 24.2 4.8 7.4e-05 22.6 4.8 1.8 1 0 0 1 1 1 1 Zinc knuckle Clavanin PF05452.11 GBG64930.1 - 0.19 12.0 0.1 0.49 10.6 0.1 1.7 1 0 0 1 1 1 0 Clavanin Jas PF16135.5 GBG64931.1 - 1.9e-15 56.8 0.1 7.3e-15 54.9 0.1 2.1 1 0 0 1 1 1 1 TPL-binding domain in jasmonate signalling Agenet PF05641.12 GBG64931.1 - 4.8e-15 55.8 0.7 6.6e-12 45.7 0.2 3.3 2 0 0 2 2 2 2 Agenet domain MBD PF01429.19 GBG64931.1 - 8.7e-05 22.2 0.2 0.00034 20.3 0.2 2.1 1 0 0 1 1 1 1 Methyl-CpG binding domain PHD PF00628.29 GBG64931.1 - 0.00011 22.0 3.0 0.00033 20.5 3.0 1.8 1 0 0 1 1 1 1 PHD-finger Acetyltransf_1 PF00583.25 GBG64931.1 - 0.0041 17.3 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family XS PF03468.14 GBG64932.1 - 1.6e-20 73.5 0.3 4.3e-19 68.9 0.3 2.5 2 0 0 2 2 2 1 XS domain DUF1515 PF07439.11 GBG64932.1 - 0.035 14.1 3.0 0.6 10.2 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF4407 PF14362.6 GBG64932.1 - 0.8 9.0 6.7 1.8 7.8 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) LUC7 PF03194.15 GBG64932.1 - 4.9 6.7 15.8 0.026 14.2 5.2 2.3 3 0 0 3 3 3 0 LUC7 N_terminus RT_RNaseH_2 PF17919.1 GBG64933.1 - 2.9e-27 94.6 0.0 8.5e-27 93.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64933.1 - 6.8e-22 77.8 0.0 2.1e-21 76.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64933.1 - 2.3e-07 30.6 0.1 1.3e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG64933.1 - 0.004 17.4 3.4 0.026 14.8 0.1 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein FAT PF02259.23 GBG64933.1 - 0.023 13.9 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 FAT domain DUF4618 PF15397.6 GBG64933.1 - 0.04 13.3 0.3 0.085 12.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) HIP1_clath_bdg PF16515.5 GBG64933.1 - 0.075 13.7 5.1 0.099 13.3 2.6 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YPEB PF14620.6 GBG64933.1 - 0.11 11.9 0.5 0.18 11.1 0.5 1.2 1 0 0 1 1 1 0 YpeB sporulation ADIP PF11559.8 GBG64933.1 - 0.18 11.8 3.7 0.5 10.4 1.9 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 GBG64933.1 - 0.28 11.5 1.8 24 5.4 0.0 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain BLOC1_2 PF10046.9 GBG64933.1 - 0.53 10.6 2.4 1.8 8.9 1.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GIT_CC PF16559.5 GBG64933.1 - 2.2 8.2 5.2 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.6 GBG64933.1 - 9.8 6.2 9.0 2.8 8.0 1.2 2.8 3 0 0 3 3 3 0 FlxA-like protein DsrH PF04077.12 GBG64934.1 - 0.027 14.6 0.3 26 5.0 0.0 4.8 2 2 6 8 8 8 0 DsrH like protein SeleniumBinding PF11524.8 GBG64934.1 - 0.41 11.1 20.6 29 5.2 0.1 7.0 1 1 6 8 8 8 0 Selenium binding protein RVT_1 PF00078.27 GBG64935.1 - 1.9e-30 106.1 0.0 3e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG64935.1 - 1.4e-11 44.1 0.0 2.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain GIY-YIG PF01541.24 GBG64936.1 - 9.3e-08 32.2 0.0 9.3e-08 32.2 0.0 3.2 4 0 0 4 4 4 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG64936.1 - 8.3e-07 28.8 1.7 1.9e-06 27.7 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-Mss51 PF13824.6 GBG64936.1 - 0.0019 18.3 0.5 0.027 14.6 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 LAL_C2 PF18603.1 GBG64936.1 - 0.78 9.9 3.7 10 6.4 1.1 2.6 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Prok-RING_1 PF14446.6 GBG64936.1 - 0.96 9.4 3.0 0.69 9.9 0.5 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 XS PF03468.14 GBG64937.1 - 1.8e-20 73.3 0.2 1.8e-20 73.3 0.2 3.4 3 0 0 3 3 3 1 XS domain Lipoprotein_6 PF01441.19 GBG64937.1 - 0.044 13.8 21.1 0.3 11.1 7.0 2.6 1 1 1 2 2 2 0 Lipoprotein DUF1515 PF07439.11 GBG64937.1 - 0.73 9.9 8.7 0.12 12.4 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF4483 PF14825.6 GBG64938.1 - 0.0004 20.2 0.8 1.1 9.0 0.4 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4483) Glycos_transf_4 PF00953.21 GBG64939.1 - 2.5e-29 102.3 7.4 2.5e-29 102.3 7.4 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 4 DHDPS PF00701.22 GBG64941.1 - 3.6e-86 288.5 0.0 4.5e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ARID PF01388.21 GBG64942.1 - 6.3e-19 68.4 0.0 2.1e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain HMG_box PF00505.19 GBG64942.1 - 1.3e-15 57.5 1.5 2.4e-15 56.7 1.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GBG64942.1 - 6.8e-07 29.8 0.5 1.2e-06 29.0 0.5 1.4 1 0 0 1 1 1 1 HMG-box domain RT_RNaseH_2 PF17919.1 GBG64943.1 - 7.7e-32 109.3 0.0 1.8e-16 60.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64943.1 - 8.7e-32 110.4 0.0 1.3e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64943.1 - 3.2e-29 101.3 0.0 6.8e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG64943.1 - 1.6e-11 43.9 0.0 3.1e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PA26 PF04636.13 GBG64944.1 - 0.29 10.0 10.3 0.39 9.6 10.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PRTP PF01366.18 GBG64944.1 - 0.97 7.4 4.0 1.4 6.9 4.0 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF3629 PF12302.8 GBG64944.1 - 2.6 7.4 9.7 4.4 6.7 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Rotamase_2 PF13145.6 GBG64944.1 - 4 8.3 13.7 0.34 11.8 1.0 2.8 1 1 1 2 2 2 0 PPIC-type PPIASE domain Herpes_UL25 PF01499.16 GBG64944.1 - 5.6 5.4 7.9 36 2.7 7.8 1.9 2 0 0 2 2 2 0 Herpesvirus UL25 family eIF3_N PF09440.10 GBG64946.1 - 5.3e-50 169.3 3.0 2.9e-49 166.9 0.5 2.3 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 GBG64946.1 - 2.3e-18 66.6 0.5 2.4e-17 63.4 0.0 2.4 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 GBG64946.1 - 0.0026 17.5 0.2 0.0051 16.5 0.2 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Methyltrans_RNA PF04452.14 GBG64947.1 - 1.9e-49 168.1 0.0 2.4e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase Prefoldin PF02996.17 GBG64948.1 - 2.1e-19 69.6 1.1 3.5e-19 68.9 1.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 GBG64948.1 - 0.0038 17.1 3.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 2 Prefoldin subunit FemAB_like PF04339.12 GBG64949.1 - 1e-29 103.9 5.0 1.6e-28 99.9 5.0 1.9 1 1 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition FemAB_like PF04339.12 GBG64950.1 - 2.5e-15 56.5 0.0 4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition RT_RNaseH_2 PF17919.1 GBG64951.1 - 2.1e-26 91.9 0.0 3.9e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64951.1 - 5.4e-24 84.5 0.0 9e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2249 PF10006.9 GBG64951.1 - 0.054 13.4 4.4 0.094 12.6 0.0 3.1 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2249) SDA1 PF05285.12 GBG64951.1 - 0.87 8.9 20.1 1.3 8.4 20.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG64951.1 - 3.3 5.8 24.3 4.4 5.4 24.3 1.1 1 0 0 1 1 1 0 Nop14-like family GPCR_chapero_1 PF11904.8 GBG64952.1 - 3.5e-89 299.3 0.0 1.2e-88 297.6 0.0 1.8 1 1 0 1 1 1 1 GPCR-chaperone Ank_5 PF13857.6 GBG64952.1 - 6.2e-07 29.6 0.0 1.7e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GBG64952.1 - 7.6e-07 29.6 0.0 2.4e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG64952.1 - 1.5e-05 25.4 0.0 0.0034 17.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG64952.1 - 0.00061 20.1 0.4 0.027 15.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GBG64952.1 - 0.00092 19.6 0.6 0.0045 17.4 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat DGF-1_C PF11040.8 GBG64952.1 - 0.092 12.8 0.1 0.092 12.8 0.1 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Ribosomal_L18p PF00861.22 GBG64953.1 - 2.6e-43 147.1 0.5 3.5e-43 146.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast CheW PF01584.19 GBG64953.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 CheW-like domain Ykof PF07615.11 GBG64953.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family DUF1118 PF06549.12 GBG64954.1 - 7.8e-44 148.7 8.0 1.3e-43 148.0 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1118) Dicty_REP PF05086.12 GBG64955.1 - 0.024 12.6 15.5 0.031 12.3 15.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Secretin_N_2 PF07655.13 GBG64955.1 - 0.1 13.1 25.0 0.95 10.1 9.7 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Mucin PF01456.17 GBG64955.1 - 0.11 12.4 12.0 0.24 11.4 12.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 GBG64955.1 - 0.29 11.1 4.4 0.56 10.2 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) BAF1_ABF1 PF04684.13 GBG64955.1 - 0.46 9.5 18.7 0.72 8.8 18.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Macoilin PF09726.9 GBG64955.1 - 0.69 8.4 10.4 0.93 8.0 10.4 1.1 1 0 0 1 1 1 0 Macoilin family Methyltransf_12 PF08242.12 GBG64955.1 - 2.3 9.0 9.9 6.2 7.6 0.8 2.7 3 0 0 3 3 3 0 Methyltransferase domain RVP_2 PF08284.11 GBG64956.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease PHD PF00628.29 GBG64959.1 - 1.6e-07 31.1 10.2 1.6e-07 31.1 10.2 2.8 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 GBG64959.1 - 0.0045 16.5 5.6 0.0045 16.5 5.6 2.9 3 0 0 3 3 3 1 PHD-finger FlpD PF02662.16 GBG64959.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit CLIP1_ZNF PF16641.5 GBG64959.1 - 9.7 6.2 7.5 7 6.7 1.3 2.6 2 0 0 2 2 2 0 CLIP1 zinc knuckle RT_RNaseH_2 PF17919.1 GBG64960.1 - 5.1e-26 90.6 0.0 1.3e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64960.1 - 1.6e-24 86.2 0.0 3.6e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG64960.1 - 4.4e-18 65.1 1.1 1e-17 64.0 1.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG64960.1 - 1.7e-06 28.2 0.0 8.2e-06 26.0 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG64960.1 - 7.2e-05 23.3 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG64960.1 - 0.00024 21.3 0.0 0.0011 19.1 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG64960.1 - 0.00029 21.4 0.0 0.00071 20.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG64960.1 - 0.0047 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG64960.1 - 0.0077 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF608 PF04685.13 GBG64961.1 - 9.7e-122 406.6 12.1 5.9e-79 265.8 4.8 3.4 2 2 2 4 4 4 3 Glycosyl-hydrolase family 116, catalytic region RT_RNaseH_2 PF17919.1 GBG64961.1 - 1.5e-20 73.1 0.0 4.3e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG64961.1 - 9.1e-10 38.8 0.0 4.5e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Glyco_hydr_116N PF12215.8 GBG64962.1 - 7.6e-66 222.7 0.0 1e-65 222.3 0.0 1.1 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term OCRL_clath_bd PF16726.5 GBG64963.1 - 0.03 14.5 0.1 0.076 13.2 0.1 1.7 1 0 0 1 1 1 0 Inositol polyphosphate 5-phosphatase clathrin binding domain Retrotrans_gag PF03732.17 GBG64963.1 - 0.099 12.9 0.4 0.49 10.7 0.1 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG64964.1 - 3.7e-08 33.2 0.0 8e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_gyraseB PF00204.25 GBG64966.1 - 3.2e-56 189.5 0.0 5.3e-56 188.8 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 GBG64966.1 - 3.5e-26 91.2 0.4 9.7e-26 89.7 0.4 1.8 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 GBG64966.1 - 2e-20 73.4 0.1 2e-19 70.1 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GBG64966.1 - 4.3e-17 62.2 0.0 1.1e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Toprim domain CDC45 PF02724.14 GBG64966.1 - 0.006 14.9 6.0 0.0092 14.3 6.0 1.2 1 0 0 1 1 1 1 CDC45-like protein HATPase_c_3 PF13589.6 GBG64966.1 - 0.029 14.2 0.0 0.089 12.6 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase P2_Phage_GpR PF06891.11 GBG64966.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) Na_trans_assoc PF06512.13 GBG64966.1 - 0.33 11.2 5.9 0.76 10.0 5.9 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4746 PF15928.5 GBG64966.1 - 1.4 8.2 11.2 2.4 7.5 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nucleo_P87 PF07267.11 GBG64966.1 - 7.7 5.2 8.2 13 4.5 8.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF262 PF03235.14 GBG64968.1 - 4.2 7.5 17.1 5.3 7.1 17.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Myb_DNA-bind_4 PF13837.6 GBG64969.1 - 4.5e-06 27.0 0.1 1.4e-05 25.3 0.1 2.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDT PF02791.17 GBG64969.1 - 0.00017 21.8 0.0 0.00042 20.6 0.0 1.6 1 0 0 1 1 1 1 DDT domain 4F5 PF04419.14 GBG64969.1 - 0.11 13.4 2.9 0.35 11.8 2.9 1.9 1 0 0 1 1 1 0 4F5 protein family Hydin_ADK PF17213.3 GBG64970.1 - 2.7 8.2 8.7 0.23 11.7 3.6 1.8 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Pro_isomerase PF00160.21 GBG64971.1 - 1.7e-09 38.2 0.0 3.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SBDS_C PF09377.10 GBG64972.1 - 7.3e-30 103.4 0.0 1e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain zf-C2H2_jaz PF12171.8 GBG64972.1 - 0.0053 17.0 1.8 0.0053 17.0 1.8 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding InaF-motif PF15018.6 GBG64972.1 - 0.035 14.0 9.9 0.069 13.0 2.7 2.3 2 0 0 2 2 2 0 TRP-interacting helix Transport_MerF PF11431.8 GBG64972.1 - 2.8 7.9 4.9 3.2 7.7 0.1 2.3 1 1 1 2 2 2 0 Membrane transport protein MerF zf-Tim10_DDP PF02953.15 GBG64974.1 - 1e-21 76.3 0.3 1.4e-21 75.9 0.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TIL PF01826.17 GBG64974.1 - 0.026 14.8 0.5 0.039 14.2 0.5 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain PHO4 PF01384.20 GBG64975.1 - 7.5e-98 327.7 16.5 8.8e-98 327.4 16.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family Humanin PF15040.6 GBG64975.1 - 0.12 11.8 0.3 0.34 10.4 0.3 1.8 1 0 0 1 1 1 0 Humanin family DUF742 PF05331.11 GBG64975.1 - 0.21 11.4 0.1 0.48 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF742) PK PF00224.21 GBG64977.1 - 1.5e-93 313.5 0.2 2.2e-93 312.9 0.2 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG64977.1 - 5.1e-23 81.5 0.6 5.8e-22 78.1 0.2 2.4 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GBG64977.1 - 0.00028 20.1 0.1 0.0026 16.9 0.0 2.3 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family RibD_C PF01872.17 GBG64977.1 - 0.00097 19.0 0.1 0.0022 17.9 0.1 1.6 1 0 0 1 1 1 1 RibD C-terminal domain BUD22 PF09073.10 GBG64978.1 - 0.086 12.2 20.9 0.12 11.7 20.9 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG64978.1 - 0.72 9.2 21.1 0.93 8.8 21.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG64978.1 - 1.5 6.9 20.6 1.9 6.6 20.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG64978.1 - 1.7 6.9 16.0 2.3 6.4 16.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Herpes_ori_bp PF02399.15 GBG64979.1 - 0.00048 18.3 0.4 0.00067 17.9 0.4 1.1 1 0 0 1 1 1 1 Origin of replication binding protein Lipoprotein_20 PF13942.6 GBG64979.1 - 0.0095 15.9 0.2 0.0095 15.9 0.2 2.2 3 0 0 3 3 3 1 YfhG lipoprotein GvpK PF05121.12 GBG64979.1 - 0.55 10.3 15.5 0.096 12.7 2.9 3.4 3 1 0 3 3 3 0 Gas vesicle protein K CLZ PF16526.5 GBG64979.1 - 2.1 8.8 13.5 1.6 9.1 3.1 3.4 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5403 PF17395.2 GBG64979.1 - 3.8 7.9 5.3 19 5.6 0.1 3.5 2 1 2 4 4 4 0 Family of unknown function (DUF5403) CM_2 PF01817.21 GBG64980.1 - 0.47 10.8 5.2 1.2 9.5 0.5 2.8 2 1 0 2 2 2 0 Chorismate mutase type II K_channel_TID PF07941.11 GBG64980.1 - 3.5 8.2 6.7 0.29 11.6 1.1 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PHO4 PF01384.20 GBG64982.1 - 2.1e-96 322.9 16.8 2.6e-96 322.6 16.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family IncD PF17628.2 GBG64982.1 - 0.0019 18.0 1.1 0.0019 18.0 1.1 2.5 3 0 0 3 3 3 1 Inclusion membrane protein D Humanin PF15040.6 GBG64982.1 - 0.15 11.5 0.3 0.37 10.3 0.3 1.6 1 0 0 1 1 1 0 Humanin family RT_RNaseH_2 PF17919.1 GBG64984.1 - 3.5e-23 81.5 0.1 6.7e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG64984.1 - 1.2e-14 54.4 0.1 1.8e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG64984.1 - 2.6e-10 40.5 0.0 4.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GFA PF04828.14 GBG64985.1 - 0.067 13.5 0.3 6.6 7.2 0.3 2.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF659 PF04937.15 GBG64987.1 - 5.8e-15 55.5 0.0 9e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG64987.1 - 0.0025 17.5 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Asp_protease_2 PF13650.6 GBG64988.1 - 0.014 16.0 0.0 0.041 14.5 0.0 1.7 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG64988.1 - 0.1 13.1 0.0 0.47 11.0 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DDE_Tnp_4 PF13359.6 GBG64990.1 - 1.4e-22 80.0 0.0 2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG64990.1 - 1.1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG64990.1 - 0.013 15.1 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG64990.1 - 0.033 14.6 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Antiterm PF03589.13 GBG64991.1 - 0.016 15.5 0.4 0.14 12.5 0.0 2.8 3 0 0 3 3 3 0 Antitermination protein OmpH PF03938.14 GBG64991.1 - 0.62 10.4 16.3 0.2 12.0 3.7 3.3 3 1 0 3 3 3 0 Outer membrane protein (OmpH-like) Syntaxin_2 PF14523.6 GBG64991.1 - 2.4 8.6 8.9 5.6 7.4 0.0 3.6 3 1 0 3 3 3 0 Syntaxin-like protein Vac_Fusion PF02346.16 GBG64991.1 - 3.3 7.4 10.3 37 4.1 4.6 4.1 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 FTO_CTD PF12934.7 GBG64991.1 - 8.1 6.2 9.4 0.41 10.4 2.5 2.2 3 0 0 3 3 3 0 FTO C-terminal domain Lyase_1 PF00206.20 GBG64992.1 - 5e-77 259.4 0.0 7.5e-77 258.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 GBG64992.1 - 1.5e-21 76.9 0.0 3.6e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF659 PF04937.15 GBG64993.1 - 2.6e-06 27.4 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3531 PF12049.8 GBG64994.1 - 4.4e-52 175.8 0.0 6.5e-52 175.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3531) LRR_4 PF12799.7 GBG64996.1 - 1.2e-14 54.2 17.7 6.3e-07 29.6 1.3 3.7 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GBG64996.1 - 1.8e-12 47.1 2.9 1e-07 31.6 1.5 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 GBG64996.1 - 8e-09 35.1 14.9 0.00021 21.0 1.6 3.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 GBG64996.1 - 0.0057 16.6 4.5 3 8.1 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 GBG64996.1 - 0.01 16.2 8.3 2.2 9.2 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat DUF1118 PF06549.12 GBG64996.1 - 0.081 13.2 1.2 15 6.0 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1118) DUF2322 PF10084.9 GBG64996.1 - 0.21 11.7 3.7 2.6 8.1 1.2 3.5 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) GIY-YIG PF01541.24 GBG64997.1 - 3.8e-06 27.1 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain AP3D1 PF06375.11 GBG64997.1 - 1.5 9.1 9.9 3.6 7.8 9.9 1.7 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 Gar1 PF04410.14 GBG64998.1 - 4.1e-36 124.1 0.0 5.3e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region NmrA PF05368.13 GBG64999.1 - 2.2e-48 164.9 0.0 2.8e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GBG64999.1 - 2.6e-16 60.1 0.1 3.3e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GBG64999.1 - 1.6e-05 24.5 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GBG64999.1 - 0.00058 19.8 0.2 0.00091 19.2 0.2 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 GBG64999.1 - 0.012 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 GBG64999.1 - 0.096 12.1 1.2 0.16 11.4 1.2 1.2 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 GBG65000.1 - 1.3e-42 146.0 0.0 1.6e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GBG65000.1 - 3.5e-13 49.9 0.0 4.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GBG65000.1 - 0.04 13.4 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GBG65001.1 - 1.4e-47 162.2 0.3 1.9e-47 161.8 0.3 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GBG65001.1 - 6.4e-16 58.8 0.2 8.7e-16 58.3 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GBG65001.1 - 7.1e-06 25.7 0.0 9.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GBG65001.1 - 0.0075 16.2 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 GBG65001.1 - 0.13 12.4 0.4 0.23 11.6 0.4 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CHRD PF07452.12 GBG65004.1 - 4.6e-10 40.5 0.4 0.00026 21.9 0.1 2.7 3 0 0 3 3 3 2 CHRD domain DUF2052 PF09747.9 GBG65005.1 - 0.0068 16.6 4.5 0.0068 16.6 4.5 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) GRP PF07172.11 GBG65005.1 - 0.017 15.8 17.9 0.02 15.6 17.9 1.1 1 0 0 1 1 1 0 Glycine rich protein family Paf1 PF03985.13 GBG65005.1 - 0.18 10.7 7.3 0.19 10.7 7.3 1.0 1 0 0 1 1 1 0 Paf1 Nop53 PF07767.11 GBG65005.1 - 0.21 10.9 7.1 0.22 10.9 7.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4637 PF15470.6 GBG65005.1 - 1.5 8.6 9.0 1.8 8.3 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CobT PF06213.12 GBG65005.1 - 1.5 8.2 8.0 1.5 8.1 8.0 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GBG65005.1 - 1.5 7.0 6.7 1.5 7.0 6.7 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG65005.1 - 7.2 5.8 10.5 8.4 5.6 10.5 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG65005.1 - 7.8 4.5 13.4 8.6 4.3 13.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Enolase_C PF00113.22 GBG65006.1 - 2.4e-158 526.0 0.6 2.9e-158 525.7 0.6 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GBG65006.1 - 7e-56 188.0 0.1 1.4e-55 187.0 0.1 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GBG65006.1 - 9.9e-10 38.3 0.0 1.8e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GBG65006.1 - 5.9e-05 22.3 0.1 0.00012 21.4 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus CHRD PF07452.12 GBG65007.1 - 1.4e-08 35.7 0.3 8.2e-05 23.6 0.1 2.5 2 0 0 2 2 2 2 CHRD domain Macin PF14865.6 GBG65007.1 - 2.4 8.7 6.2 2 9.0 2.7 2.6 2 1 1 3 3 3 0 Macin DUF1943 PF09172.11 GBG65008.1 - 2.6 7.2 7.8 3.3 6.9 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) DUF1943 PF09172.11 GBG65009.1 - 1 8.5 4.5 2.1 7.5 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) LRIF1 PF15741.5 GBG65009.1 - 6.9 5.1 8.3 10 4.5 8.3 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 zf-CCHC PF00098.23 GBG65011.1 - 5.9e-06 26.1 1.8 1.2e-05 25.1 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG65011.1 - 0.01 15.7 0.5 0.019 14.8 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG65011.1 - 2.3 8.3 6.5 0.28 11.2 1.5 2.0 2 0 0 2 2 2 0 Zinc knuckle XRN_M PF17846.1 GBG65011.1 - 9.2 5.1 9.7 19 4.0 9.7 1.5 1 0 0 1 1 1 0 Xrn1 helical domain WD40 PF00400.32 GBG65012.1 - 3.1e-23 81.6 21.7 7.3e-06 26.6 0.0 8.4 8 1 0 8 8 8 7 WD domain, G-beta repeat TMEM171 PF15471.6 GBG65012.1 - 3.7 6.4 4.9 7 5.5 4.9 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF4682 PF15733.5 GBG65012.1 - 8.2 7.0 6.0 16 6.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4682) RT_RNaseH_2 PF17919.1 GBG65014.1 - 6.8e-31 106.3 0.0 5e-15 55.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65014.1 - 1.4e-28 99.9 0.1 2.2e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65014.1 - 3.1e-28 98.1 0.0 7.3e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65014.1 - 8.4e-15 54.6 0.0 3.7e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG65014.1 - 7.7e-13 48.7 0.0 2.1e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65014.1 - 0.017 15.3 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger N6_N4_Mtase PF01555.18 GBG65015.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 DNA methylase gag-asp_proteas PF13975.6 GBG65016.1 - 5.7e-05 23.6 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65016.1 - 0.0049 17.5 0.0 0.01 16.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease PRP1_N PF06424.12 GBG65016.1 - 0.17 12.2 8.9 0.04 14.3 5.5 1.6 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal RXLR PF16810.5 GBG65016.1 - 0.6 10.5 4.0 1.2 9.5 4.0 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity CDC45 PF02724.14 GBG65016.1 - 5 5.3 7.6 6.7 4.9 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 GBG65016.1 - 5.5 6.7 7.3 13 5.4 7.3 1.6 1 0 0 1 1 1 0 FAM176 family rve PF00665.26 GBG65017.1 - 5.3e-10 39.5 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG65017.1 - 0.021 14.6 0.0 0.071 12.9 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG65017.1 - 0.078 13.3 0.2 0.47 10.8 0.1 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG65017.1 - 0.095 13.3 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG65017.1 - 0.097 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG65018.1 - 6.8e-31 107.5 0.0 1.1e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65018.1 - 2.2e-14 53.3 0.1 5.6e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65018.1 - 6.6e-12 45.7 0.0 1.9e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65018.1 - 0.0053 16.9 0.1 0.016 15.5 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG65018.1 - 0.055 14.1 0.0 0.2 12.3 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease HTH_20 PF12840.7 GBG65018.1 - 0.14 12.3 2.7 3.8 7.6 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain RVP_2 PF08284.11 GBG65019.1 - 1.8e-08 34.2 0.0 3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG65019.1 - 1.5e-05 25.5 0.0 3.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65019.1 - 5.3e-05 23.8 0.0 0.0001 22.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG65019.1 - 0.0032 17.2 0.0 0.0073 16.1 0.0 1.6 1 1 0 1 1 1 1 Putative peptidase (DUF1758) Inovirus_Gp2 PF11726.8 GBG65019.1 - 0.092 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Inovirus Gp2 DUF659 PF04937.15 GBG65020.1 - 8.7e-14 51.6 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG65021.1 - 1.6e-32 111.5 0.0 3.6e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65021.1 - 6.5e-28 97.1 0.1 1.6e-27 95.8 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65021.1 - 4.4e-14 52.7 0.1 1.2e-13 51.2 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG65021.1 - 1.8e-12 47.3 0.1 4.3e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG65021.1 - 0.45 10.5 3.5 1.1 9.3 3.5 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG65022.1 - 1.3e-24 86.2 0.0 4.4e-24 84.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65022.1 - 5.9e-23 81.2 0.0 1.1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65022.1 - 1.2e-19 70.1 0.1 2.8e-19 69.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65022.1 - 5.6e-19 68.5 0.0 1.4e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG65022.1 - 0.0014 18.5 0.3 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG65022.1 - 0.0032 17.3 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG65022.1 - 0.0051 17.0 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF2389 PF09493.10 GBG65022.1 - 0.29 11.8 1.2 2.1 9.0 0.1 2.9 4 0 0 4 4 4 0 Tryptophan-rich protein (DUF2389) MscS_porin PF12795.7 GBG65022.1 - 0.59 9.6 3.5 1 8.8 3.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Relaxase PF03432.14 GBG65023.1 - 0.22 11.1 5.6 0.13 11.8 1.8 2.3 1 1 1 2 2 2 0 Relaxase/Mobilisation nuclease domain CCDC50_N PF15295.6 GBG65023.1 - 6.2 7.0 11.7 0.16 12.1 4.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus PPP4R2 PF09184.11 GBG65024.1 - 1.4 8.5 17.8 1.7 8.1 17.8 1.3 1 0 0 1 1 1 0 PPP4R2 DUF659 PF04937.15 GBG65025.1 - 1.6e-12 47.6 0.3 4.7e-12 46.0 0.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65025.1 - 5.3e-05 22.9 0.2 0.00015 21.5 0.2 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MttA_Hcf106 PF02416.16 GBG65028.1 - 1.6e-22 78.5 0.1 2.9e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 mttA/Hcf106 family PapC_C PF13953.6 GBG65030.1 - 0.0078 16.0 22.5 1 9.2 1.4 5.7 1 1 5 6 6 6 6 PapC C-terminal domain Toprim_N PF08275.11 GBG65030.1 - 0.11 12.5 6.9 63 3.6 0.0 5.2 1 1 5 6 6 6 0 DNA primase catalytic core, N-terminal domain RTA1 PF04479.13 GBG65030.1 - 0.9 9.1 5.8 25 4.4 0.0 4.5 1 1 5 6 6 6 0 RTA1 like protein DUF2917 PF11142.8 GBG65030.1 - 1 8.8 7.8 5.2 6.6 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2917) ImpE PF07024.13 GBG65030.1 - 1.6 8.9 6.8 27 4.9 0.3 4.0 2 1 0 4 4 4 0 ImpE protein rve PF00665.26 GBG65031.1 - 4.9e-11 42.9 0.0 1e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG65031.1 - 6.8e-05 23.4 0.0 0.00026 21.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG65031.1 - 0.001 19.3 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65031.1 - 0.01 16.5 0.0 0.032 14.9 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG65031.1 - 0.015 15.1 0.2 0.059 13.2 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease rve_3 PF13683.6 GBG65031.1 - 0.021 14.6 0.0 0.08 12.7 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG65031.1 - 0.083 12.4 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65032.1 - 1.6e-33 114.7 0.1 3.1e-33 113.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65032.1 - 6.4e-30 103.5 0.0 1.4e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65032.1 - 2.3e-18 66.1 0.1 4.5e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65032.1 - 2.5e-15 56.7 0.0 8.9e-15 54.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG65032.1 - 3.5e-05 23.4 0.0 0.00019 21.0 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG65032.1 - 0.0002 21.8 0.0 0.00048 20.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG65032.1 - 0.00068 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG65032.1 - 0.0027 17.5 0.1 0.0094 15.7 0.0 1.8 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG65032.1 - 0.0066 17.1 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG65032.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Chromo PF00385.24 GBG65033.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TMEM247 PF15444.6 GBG65033.1 - 0.079 13.0 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 MscS_TM PF12794.7 GBG65033.1 - 1 8.2 8.8 0.16 10.8 0.2 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 rve PF00665.26 GBG65035.1 - 3.5e-32 111.1 0.1 5.9e-16 58.7 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG65035.1 - 9.5e-20 70.5 0.9 2.3e-19 69.2 0.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG65035.1 - 8e-07 29.3 0.0 2.5e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65035.1 - 0.00014 21.9 0.0 0.00035 20.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG65035.1 - 0.0094 16.2 0.1 0.039 14.2 0.1 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG65035.1 - 0.014 15.6 0.3 0.035 14.3 0.3 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF4148 PF13663.6 GBG65035.1 - 0.099 12.8 3.0 0.28 11.4 3.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) NPV_P10 PF05531.12 GBG65035.1 - 0.27 11.7 0.7 5.5 7.5 0.3 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Filament_head PF04732.14 GBG65035.1 - 3.5 8.6 5.5 13 6.7 5.5 2.0 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region Retrotrans_gag PF03732.17 GBG65036.1 - 0.0023 18.1 1.3 0.009 16.3 0.1 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG65036.1 - 0.037 13.4 6.7 0.028 13.8 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RT_RNaseH PF17917.1 GBG65037.1 - 1.9e-21 76.3 0.0 6.8e-21 74.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65037.1 - 8.9e-21 73.8 0.0 2.3e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65037.1 - 1.2e-17 63.8 0.2 2.5e-17 62.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65037.1 - 7.4e-16 58.3 0.0 2.3e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG65037.1 - 1.2e-06 29.0 0.0 3.2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65037.1 - 1e-05 25.3 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG65037.1 - 0.00022 21.7 0.0 0.00073 20.0 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG65037.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG65037.1 - 0.065 13.5 0.0 0.28 11.5 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4510 PF14971.6 GBG65037.1 - 2.9 8.2 7.1 8 6.8 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DUF2408 PF10303.9 GBG65037.1 - 3.1 8.4 5.4 3.3 8.3 0.0 2.8 2 1 0 3 3 2 0 Protein of unknown function (DUF2408) RVT_1 PF00078.27 GBG65039.1 - 6.8e-15 55.2 0.3 1.4e-14 54.2 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tify PF06200.14 GBG65039.1 - 7.3e-15 54.0 0.2 1.5e-14 53.0 0.2 1.5 1 0 0 1 1 1 1 tify domain DDE_Tnp_4 PF13359.6 GBG65040.1 - 2.6e-30 105.2 0.0 4.1e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65040.1 - 1e-15 57.9 0.0 1.6e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG65040.1 - 5.5e-06 26.2 0.1 0.093 12.4 0.2 2.2 2 0 0 2 2 2 2 Transposase DDE domain Toxin_29 PF08116.11 GBG65041.1 - 0.093 12.7 0.2 11 6.1 0.0 2.3 2 0 0 2 2 2 0 PhTx neurotoxin family Asp_protease_2 PF13650.6 GBG65043.1 - 7.4e-08 32.9 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65043.1 - 5.7e-07 30.0 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG65043.1 - 7.9e-06 25.7 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG65043.1 - 3.1e-05 24.2 0.0 0.00012 22.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG65043.1 - 0.00016 21.5 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG65043.1 - 0.0034 17.6 0.1 0.0087 16.3 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein FKBP_C PF00254.28 GBG65044.1 - 9.6e-31 106.0 0.0 2.3e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 GBG65044.1 - 1e-15 58.2 0.0 1e-15 58.2 0.0 3.2 2 1 0 2 2 2 1 Nucleoplasmin-like domain Utp14 PF04615.13 GBG65044.1 - 2.1 6.8 42.2 3.3 6.2 42.2 1.2 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 GBG65044.1 - 3.3 6.2 12.9 4.3 5.8 12.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF659 PF04937.15 GBG65047.1 - 4e-35 120.9 0.0 1.1e-34 119.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65047.1 - 0.0032 17.2 1.1 0.0068 16.2 0.3 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG65048.1 - 1.1e-31 108.8 0.0 2.3e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65048.1 - 2.1e-26 92.2 0.1 4.7e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65048.1 - 2.5e-14 53.5 0.1 8.2e-14 51.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG65048.1 - 3.7e-06 27.4 0.0 1.1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65048.1 - 0.0014 19.2 0.0 0.0031 18.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65048.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TBCA PF02970.16 GBG65048.1 - 0.074 13.4 0.5 0.2 12.0 0.5 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF2267 PF10025.9 GBG65048.1 - 0.083 13.2 1.8 1.8 8.8 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) NUDIX PF00293.28 GBG65049.1 - 2.6e-13 50.2 0.0 3.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain RT_RNaseH PF17917.1 GBG65050.1 - 1.2e-28 99.5 0.0 3.2e-28 98.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65050.1 - 5.3e-20 71.3 0.0 1.3e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65051.1 - 2.9e-28 98.9 0.1 4.7e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG65051.1 - 0.0028 18.3 0.0 0.013 16.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Hormone_3 PF00159.18 GBG65051.1 - 0.026 14.6 0.1 0.14 12.3 0.1 2.4 1 0 0 1 1 1 0 Pancreatic hormone peptide RT_RNaseH_2 PF17919.1 GBG65052.1 - 5.4e-59 196.4 0.0 2.9e-29 101.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65052.1 - 1e-46 157.5 0.6 9.9e-30 102.9 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65052.1 - 4e-30 105.0 0.0 7.2e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG65052.1 - 0.062 12.9 0.1 0.062 12.9 0.1 3.6 3 1 1 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase APC1_C PF18122.1 GBG65052.1 - 1.9 8.4 4.6 1.2 9.1 1.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain Herpes_UL25 PF01499.16 GBG65052.1 - 2.1 6.7 8.8 4.4 5.7 8.8 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family RSS_P20 PF11757.8 GBG65052.1 - 2.8 8.5 7.0 0.78 10.2 2.1 2.7 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain RT_RNaseH PF17917.1 GBG65053.1 - 2.1e-22 79.4 0.0 4.7e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65053.1 - 4.2e-20 71.7 0.0 8.4e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65053.1 - 3e-16 59.7 0.0 6.6e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG65053.1 - 7.2e-15 54.9 0.2 7.2e-15 54.9 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 GBG65053.1 - 0.0013 18.4 0.0 0.0041 16.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65053.1 - 0.0033 17.6 2.5 0.052 13.8 0.1 2.7 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease PF09668.10 GBG65053.1 - 0.0044 16.8 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG65053.1 - 0.0062 16.6 1.3 0.019 15.0 1.3 1.9 1 0 0 1 1 1 1 Zinc knuckle Cytotoxic PF09000.10 GBG65053.1 - 3.3 8.1 8.1 2.6 8.4 3.1 3.2 3 0 0 3 3 3 0 Cytotoxic RT_RNaseH_2 PF17919.1 GBG65054.1 - 2e-13 50.2 0.0 4.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65054.1 - 3.7e-09 36.8 0.0 8.1e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG65054.1 - 0.0058 17.2 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65054.1 - 0.052 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG65054.1 - 0.074 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 GBG65054.1 - 0.077 13.3 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG65055.1 - 6.4e-06 25.9 1.0 1e-05 25.2 1.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG65056.1 - 2.7e-35 121.9 0.1 4.2e-35 121.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65056.1 - 7.5e-29 99.7 0.0 2.3e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65056.1 - 2.7e-28 98.3 0.0 5.8e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65056.1 - 2e-18 66.2 0.7 4.5e-18 65.1 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG65056.1 - 0.015 15.5 0.5 0.047 13.9 0.4 1.9 2 0 0 2 2 2 0 H2C2 zinc finger RVT_1 PF00078.27 GBG65057.1 - 8.6e-25 87.5 0.2 2.1e-24 86.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65057.1 - 8.3e-24 83.5 0.0 1.8e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65057.1 - 6.8e-23 81.0 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65057.1 - 1.6e-13 50.5 0.0 3.5e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG65058.1 - 3.2e-06 27.6 0.2 8.3e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65058.1 - 0.00012 22.6 0.0 0.00034 21.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65058.1 - 0.003 17.4 0.8 0.0062 16.3 0.8 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG65058.1 - 0.022 15.0 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein LCD1 PF09798.9 GBG65059.1 - 0.23 9.9 8.1 0.34 9.4 8.1 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein CENP-Q PF13094.6 GBG65059.1 - 3.4 7.9 11.3 9.4 6.4 11.1 1.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Integrase_H2C2 PF17921.1 GBG65060.1 - 3.4e-14 52.7 0.1 6.9e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain T3SS_needle_E PF08988.10 GBG65060.1 - 0.0012 19.0 0.4 0.0012 19.0 0.4 2.2 2 0 0 2 2 2 1 Type III secretion system, cytoplasmic E component of needle zf-H2C2 PF09337.10 GBG65060.1 - 0.034 14.4 0.1 0.088 13.0 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF4139 PF13598.6 GBG65060.1 - 0.067 12.9 0.0 0.68 9.6 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4139) DUF1731 PF08338.11 GBG65060.1 - 0.17 11.7 0.9 1.6 8.7 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1731) RT_RNaseH_2 PF17919.1 GBG65061.1 - 4.5e-22 78.0 0.0 8.2e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65061.1 - 2.8e-21 75.8 0.0 5.9e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65061.1 - 5e-14 52.5 0.0 1.2e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG65061.1 - 7.2e-12 45.2 0.0 2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG65061.1 - 0.0049 16.6 0.0 0.019 14.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG65065.1 - 7.8e-05 22.6 2.6 7.8e-05 22.6 2.6 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG65065.1 - 0.0021 17.8 7.5 0.0021 17.8 7.5 1.8 2 0 0 2 2 2 1 Zinc knuckle Prok-JAB PF14464.6 GBG65065.1 - 0.12 12.1 0.7 0.26 11.1 0.4 1.7 1 1 0 1 1 1 0 Prokaryotic homologs of the JAB domain DUF760 PF05542.11 GBG65065.1 - 0.13 12.6 0.7 0.29 11.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF760) eIF3g PF12353.8 GBG65065.1 - 0.13 12.6 0.1 0.13 12.6 0.1 3.8 3 1 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Cep57_CLD_2 PF14197.6 GBG65065.1 - 4.9 7.3 26.4 0.06 13.4 4.8 4.1 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 BT1 PF03092.16 GBG65065.1 - 8.1 4.5 9.3 1.2 7.2 5.5 1.4 1 1 1 2 2 2 0 BT1 family zf-CCHC_4 PF14392.6 GBG65066.1 - 0.011 15.4 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle IBB PF01749.20 GBG65066.1 - 0.029 14.8 4.4 0.067 13.6 3.7 2.0 1 1 0 1 1 1 0 Importin beta binding domain zf-CCHC PF00098.23 GBG65066.1 - 0.1 12.7 4.1 0.18 11.9 4.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG65066.1 - 1.4 8.8 3.8 3.5 7.6 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG65069.1 - 4.1e-33 113.4 0.0 1e-32 112.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65069.1 - 7.6e-30 103.3 0.1 2.1e-29 101.9 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG65069.1 - 0.0021 18.3 0.1 0.081 13.2 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG65070.1 - 2.7e-63 213.4 1.2 1.5e-31 109.7 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65070.1 - 1.7e-59 198.1 0.0 9.6e-33 112.2 0.0 3.4 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65070.1 - 1.2e-44 150.9 0.0 5.4e-21 74.8 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65070.1 - 9e-18 64.1 0.2 3.7e-17 62.2 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG65070.1 - 6.5e-13 48.9 0.1 3.1e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG65070.1 - 2.8e-07 30.7 2.7 0.005 17.1 0.1 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG65070.1 - 0.13 12.5 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger MerR-DNA-bind PF09278.11 GBG65072.1 - 0.089 13.3 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 MerR, DNA binding Leu_zip PF15294.6 GBG65072.1 - 0.31 10.5 6.7 0.53 9.8 6.7 1.3 1 0 0 1 1 1 0 Leucine zipper RVT_1 PF00078.27 GBG65073.1 - 1.2e-30 106.7 0.0 1.9e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65073.1 - 4.1e-18 65.6 0.3 8.7e-18 64.5 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65073.1 - 8.2e-17 61.1 0.0 3.4e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG65073.1 - 9.6e-10 38.4 0.1 2.1e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG65073.1 - 2.6e-06 27.6 0.0 6.5e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger SlyX PF04102.12 GBG65073.1 - 0.67 10.6 6.0 0.44 11.2 0.1 3.4 3 0 0 3 3 3 0 SlyX RT_RNaseH_2 PF17919.1 GBG65074.1 - 4.4e-32 110.1 0.0 8.2e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65074.1 - 1.7e-28 99.0 0.1 3.3e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65074.1 - 1.8e-24 86.5 0.1 3.3e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65074.1 - 3.5e-18 65.5 0.7 7.8e-18 64.3 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65074.1 - 2.1e-11 44.1 0.0 5.9e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65074.1 - 9e-05 22.6 0.1 0.00048 20.3 0.1 2.3 2 0 0 2 2 2 1 H2C2 zinc finger DUF1564 PF07600.11 GBG65074.1 - 0.016 14.9 0.7 0.05 13.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG65074.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG65076.1 - 1.8e-27 96.3 0.1 3.4e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65076.1 - 2.1e-21 75.8 0.0 6.4e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65076.1 - 4.1e-20 72.0 0.0 9e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65076.1 - 3.5e-16 59.0 0.7 9.5e-16 57.7 0.5 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG65076.1 - 4.7e-10 39.7 0.0 1.5e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG65076.1 - 2e-08 34.8 0.0 5.2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65076.1 - 6.1e-08 33.1 0.0 1.8e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG65076.1 - 4.2e-07 29.8 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG65076.1 - 0.00014 21.6 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG65076.1 - 0.042 14.1 0.3 0.11 12.7 0.3 1.8 1 0 0 1 1 1 0 H2C2 zinc finger ANXA2R PF15721.5 GBG65077.1 - 6 7.4 11.6 3.6 8.1 2.8 2.2 1 1 1 2 2 2 0 Annexin-2 receptor DUF3194 PF11419.8 GBG65078.1 - 0.0081 16.5 1.3 0.021 15.1 0.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3194) Cluap1 PF10234.9 GBG65078.1 - 0.023 14.1 2.2 0.024 14.1 0.6 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF659 PF04937.15 GBG65079.1 - 4.4e-35 120.8 0.0 7e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65079.1 - 3e-08 33.3 0.0 5.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Caldesmon PF02029.15 GBG65079.1 - 2.2 6.9 42.7 4.5 5.9 42.7 1.4 1 0 0 1 1 1 0 Caldesmon rve PF00665.26 GBG65080.1 - 4.8e-09 36.4 0.0 1.3e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG65080.1 - 0.00083 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG65080.1 - 0.0057 16.4 0.2 3.6 7.4 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain DUF1768 PF08719.11 GBG65080.1 - 0.094 13.0 6.6 0.71 10.1 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1768) RT_RNaseH PF17917.1 GBG65081.1 - 1.7e-29 102.1 0.1 4.1e-29 101.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65081.1 - 1.3e-28 98.9 0.0 3.4e-28 97.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65081.1 - 1.2e-19 70.1 0.5 2.9e-19 68.9 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG65081.1 - 0.00067 19.8 0.1 0.0019 18.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG65081.1 - 0.00077 19.7 0.7 0.0064 16.7 0.0 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG65082.1 - 4.3e-27 95.1 0.1 2.3e-26 92.7 0.1 2.3 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65082.1 - 1.2e-22 80.2 0.0 3.7e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65082.1 - 5.3e-22 77.7 0.0 2e-21 75.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG65082.1 - 6.2e-08 33.2 0.0 4.9e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG65082.1 - 7.9e-08 32.1 0.0 1.9e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG65082.1 - 3.1e-06 27.6 0.0 3.3e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG65082.1 - 0.00013 21.8 0.0 0.00038 20.3 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG65082.1 - 0.0043 16.8 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease WTX PF09422.10 GBG65082.1 - 0.0054 15.9 1.0 0.012 14.7 1.0 1.5 1 0 0 1 1 1 1 WTX protein Retrotrans_gag PF03732.17 GBG65082.1 - 0.075 13.3 0.0 0.34 11.2 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein Chromo PF00385.24 GBG65082.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TolA_bind_tri PF16331.5 GBG65082.1 - 0.25 11.4 8.0 0.87 9.7 8.0 2.0 1 0 0 1 1 1 0 TolA binding protein trimerisation IL28A PF15177.6 GBG65082.1 - 0.65 9.8 7.5 2.1 8.2 7.5 1.9 1 0 0 1 1 1 0 Interleukin-28A SlyX PF04102.12 GBG65082.1 - 3.2 8.5 10.3 1.7 9.3 1.9 3.9 4 0 0 4 4 4 0 SlyX RVT_1 PF00078.27 GBG65084.1 - 2.6e-31 108.9 0.0 4.1e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65084.1 - 1.8e-23 82.8 0.0 4.9e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65084.1 - 9.5e-17 60.9 0.3 4.5e-16 58.7 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG65084.1 - 0.0093 15.9 0.5 0.023 14.6 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 GBG65084.1 - 0.48 10.9 9.4 1.6 9.2 9.4 1.9 1 0 0 1 1 1 0 AAA domain DUF3629 PF12302.8 GBG65084.1 - 7.8 5.9 7.6 14 5.0 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DsrH PF04077.12 GBG65085.1 - 0.00012 22.1 3.0 1.6e+02 2.5 0.0 8.6 6 5 7 13 13 13 0 DsrH like protein Urocanase PF01175.18 GBG65085.1 - 0.022 14.4 3.0 16 5.0 0.0 4.7 2 2 1 3 3 3 0 Urocanase Rossmann-like domain DUF4860 PF16152.5 GBG65085.1 - 1.4 8.9 6.5 10 6.0 0.2 4.1 2 2 3 5 5 5 0 Domain of unknown function (DUF4860) HTH_Tnp_1 PF01527.20 GBG65085.1 - 3.1 8.2 23.1 8.8 6.7 0.1 6.9 2 2 4 6 6 6 0 Transposase RVT_1 PF00078.27 GBG65087.1 - 2.4e-27 95.9 0.0 4.2e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65087.1 - 8.7e-25 86.7 0.0 3.5e-12 46.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65087.1 - 1.3e-15 57.5 0.0 3.2e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG65087.1 - 1.5e-10 40.8 0.0 3.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG65087.1 - 1.6e-08 34.8 0.0 5.6e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG65088.1 - 2.3e-23 82.9 0.2 9.2e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65088.1 - 1.7e-22 79.3 0.0 6e-22 77.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65088.1 - 2.6e-22 79.1 0.0 1.1e-21 77.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG65088.1 - 0.0099 16.1 8.2 0.029 14.6 0.3 4.4 4 0 0 4 4 4 1 Retrotransposon gag protein FlxA PF14282.6 GBG65088.1 - 0.015 15.3 2.3 0.015 15.3 2.3 3.0 2 2 0 2 2 2 0 FlxA-like protein AbiJ_NTD5 PF18865.1 GBG65088.1 - 0.081 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 FAM76 PF16046.5 GBG65088.1 - 1.2 8.4 5.7 2.7 7.3 5.7 1.5 1 0 0 1 1 1 0 FAM76 protein RT_RNaseH PF17917.1 GBG65090.1 - 6.1e-13 49.0 0.1 6.5e-12 45.7 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65090.1 - 5e-07 29.7 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65090.1 - 0.0002 21.6 0.0 0.00065 19.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG65090.1 - 0.002 18.4 0.1 0.0084 16.4 0.1 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.24 GBG65090.1 - 0.0074 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG65090.1 - 0.0098 15.7 0.9 0.042 13.6 0.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) TMEM247 PF15444.6 GBG65090.1 - 0.032 14.3 0.1 0.032 14.3 0.1 3.6 4 0 0 4 4 4 0 Transmembrane protein 247 Nop14 PF04147.12 GBG65091.1 - 0.0064 14.8 8.0 0.0077 14.5 8.0 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG65091.1 - 0.028 13.8 10.9 0.038 13.4 10.9 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG65091.1 - 0.046 12.0 11.3 0.056 11.7 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG65091.1 - 0.11 12.6 16.2 0.15 12.1 16.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GBG65091.1 - 0.28 10.9 11.8 0.36 10.5 11.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PTPRCAP PF15713.5 GBG65091.1 - 1.1 9.6 14.0 1.8 8.9 14.0 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF936 PF06075.12 GBG65093.1 - 1.3e-87 295.4 0.1 5.4e-74 250.4 0.0 2.2 2 0 0 2 2 2 2 Plant protein of unknown function (DUF936) Rep-A_N PF04057.12 GBG65093.1 - 0.0047 16.9 0.0 0.0098 15.9 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain PSI_PSAK PF01241.18 GBG65096.1 - 0.00075 19.5 0.0 0.36 10.9 0.0 2.2 2 0 0 2 2 2 2 Photosystem I psaG / psaK Phage_holin_2_2 PF10746.9 GBG65096.1 - 0.045 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II Cyt_c_ox_IV PF12270.8 GBG65096.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Pkinase PF00069.25 GBG65097.1 - 2.4e-12 46.8 0.0 2.8e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG65097.1 - 7.3e-06 25.4 0.0 8.3e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PRP38_assoc PF12871.7 GBG65098.1 - 0.0004 21.0 43.5 0.0004 21.0 43.5 4.4 3 0 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term XRCC1_N PF01834.16 GBG65098.1 - 0.028 14.4 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 XRCC1 N terminal domain Trypan_PARP PF05887.11 GBG65098.1 - 7.7 6.5 6.4 0.95 9.4 0.6 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PRP38_assoc PF12871.7 GBG65099.1 - 0.00039 21.0 43.5 0.00039 21.0 43.5 4.4 3 0 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term XRCC1_N PF01834.16 GBG65099.1 - 0.028 14.4 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 XRCC1 N terminal domain Trypan_PARP PF05887.11 GBG65099.1 - 7.6 6.5 6.4 0.94 9.5 0.6 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TMCO5 PF14992.6 GBG65100.1 - 3.8 7.0 10.0 2 8.0 4.1 2.0 1 1 1 2 2 2 0 TMCO5 family Na_H_Exchanger PF00999.21 GBG65101.1 - 3.4e-22 78.8 40.5 9.3e-22 77.3 38.6 2.4 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family RVT_1 PF00078.27 GBG65102.1 - 1.5e-32 112.9 0.3 1.1e-31 110.1 0.3 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65102.1 - 1.7e-29 101.8 0.0 8.5e-29 99.5 0.0 2.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65102.1 - 4.1e-28 97.7 0.0 1.8e-27 95.7 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65102.1 - 1.3e-14 54.0 0.1 3.5e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG65102.1 - 5.5e-07 29.4 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65102.1 - 1.3e-05 25.7 0.0 3.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG65102.1 - 0.0013 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG65102.1 - 0.0015 19.1 0.1 0.011 16.2 0.0 2.5 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG65102.1 - 0.081 13.2 0.2 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger DUF4392 PF14336.6 GBG65102.1 - 0.1 12.0 0.4 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Phage_GPO PF05929.11 GBG65102.1 - 0.38 10.3 0.0 0.38 10.3 0.0 3.3 2 1 0 2 2 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Sod_Fe_C PF02777.18 GBG65103.1 - 6.9e-36 122.5 0.2 1.4e-35 121.5 0.0 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GBG65103.1 - 4.2e-30 104.0 3.5 7.5e-30 103.3 3.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain SR-25 PF10500.9 GBG65104.1 - 1.9 8.0 32.4 2.5 7.7 14.4 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DnaJ PF00226.31 GBG65105.1 - 6.3e-16 58.3 0.1 1.1e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain K_channel_TID PF07941.11 GBG65105.1 - 0.00049 20.5 11.8 0.0027 18.1 11.8 2.3 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain Ribosomal_60s PF00428.19 GBG65105.1 - 1.2 9.8 8.7 0.39 11.4 5.1 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein TAF4 PF05236.14 GBG65105.1 - 2.8 7.6 5.8 0.45 10.2 1.2 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Myb_DNA-bind_4 PF13837.6 GBG65107.1 - 0.00017 21.9 0.7 0.0007 19.9 0.3 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain GCIP PF13324.6 GBG65107.1 - 0.0014 18.3 6.9 0.0025 17.5 6.9 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GBG65107.1 - 0.0026 15.9 16.7 0.0039 15.4 16.7 1.1 1 0 0 1 1 1 1 DNA polymerase phi Myb_DNA-bind_5 PF13873.6 GBG65107.1 - 0.0031 17.5 0.6 0.005 16.9 0.6 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF1676 PF07898.13 GBG65107.1 - 0.0057 16.7 0.1 0.013 15.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) Orf78 PF06024.12 GBG65107.1 - 0.019 15.2 0.3 0.039 14.3 0.3 1.4 1 0 0 1 1 1 0 Orf78 (ac78) RRN3 PF05327.11 GBG65107.1 - 0.044 12.3 9.9 0.058 11.9 9.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 GBG65107.1 - 0.054 12.9 5.9 0.088 12.2 5.9 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG65107.1 - 0.27 9.4 9.9 0.38 8.9 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 GBG65107.1 - 0.29 10.7 7.1 0.43 10.1 7.1 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4736 PF15883.5 GBG65107.1 - 0.42 10.3 2.5 0.63 9.7 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) BUD22 PF09073.10 GBG65107.1 - 1.7 7.9 11.1 3 7.1 11.1 1.4 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 GBG65107.1 - 2.5 8.0 14.1 3.6 7.5 14.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.13 GBG65107.1 - 2.7 7.9 10.2 5 6.9 10.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.9 GBG65107.1 - 3 6.9 26.8 5.4 6.0 26.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cnd2 PF05786.14 GBG65107.1 - 7.4 5.1 17.7 12 4.4 17.7 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 Integrase_H2C2 PF17921.1 GBG65108.1 - 4.5e-17 61.9 0.6 1.1e-16 60.6 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65108.1 - 1.3e-16 60.8 0.0 3.3e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG65108.1 - 7.7e-15 55.1 0.0 2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65108.1 - 6.9e-12 45.3 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG65108.1 - 0.052 13.6 1.9 0.14 12.3 1.9 1.8 1 0 0 1 1 1 0 Zinc knuckle Phage_portal PF04860.12 GBG65111.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein RVT_1 PF00078.27 GBG65113.1 - 7.2e-11 42.0 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_H_Exchanger PF00999.21 GBG65114.1 - 2.2e-23 82.7 31.0 9e-23 80.7 31.0 1.9 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family zf-CCHC_6 PF15288.6 GBG65115.1 - 0.0047 16.7 0.3 0.01 15.7 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle MCM_bind PF09739.9 GBG65115.1 - 1.7 7.0 5.4 2.5 6.4 5.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor ALS_ss_C PF10369.9 GBG65116.1 - 7.3e-53 176.7 7.6 2.2e-26 91.9 0.9 2.8 3 0 0 3 3 3 2 Small subunit of acetolactate synthase ACT PF01842.25 GBG65116.1 - 4.4e-25 87.1 0.7 1.5e-12 47.0 0.0 2.8 2 1 0 2 2 2 2 ACT domain ACT_5 PF13710.6 GBG65116.1 - 1.3e-24 85.7 0.1 1e-11 44.5 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 GBG65116.1 - 6.4e-10 39.5 1.5 0.0028 18.2 0.0 3.6 2 2 1 3 3 3 2 ACT domain ACT_6 PF13740.6 GBG65116.1 - 0.0094 15.9 1.1 1.5 8.8 0.0 3.3 2 1 1 3 3 3 1 ACT domain YtxH PF12732.7 GBG65117.1 - 0.024 15.2 0.8 9.6 6.8 0.2 2.4 2 0 0 2 2 2 0 YtxH-like protein SDH_sah PF01972.16 GBG65117.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase RT_RNaseH_2 PF17919.1 GBG65118.1 - 2.3e-30 104.6 0.0 5.4e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65118.1 - 5.7e-30 103.7 0.1 1.4e-29 102.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65118.1 - 4.9e-08 32.8 0.0 9.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_HK97_TLTM PF06120.11 GBG65118.1 - 4.6 6.3 12.6 7.5 5.6 12.6 1.3 1 0 0 1 1 1 0 Tail length tape measure protein MFS_1 PF07690.16 GBG65119.1 - 9.3e-57 192.5 28.3 9.3e-57 192.5 28.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ATE_C PF04377.15 GBG65120.1 - 1.7e-37 129.1 0.0 3.8e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 GBG65120.1 - 7.2e-21 74.4 1.8 2.5e-20 72.6 1.8 2.0 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Arg_tRNA_synt_N PF03485.16 GBG65120.1 - 0.0086 16.6 0.1 0.019 15.5 0.1 1.6 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain RT_RNaseH_2 PF17919.1 GBG65121.1 - 1.4e-28 98.8 0.0 4.8e-28 97.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65121.1 - 1.5e-27 96.0 0.0 6.1e-27 94.0 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65121.1 - 1.7e-11 44.1 0.0 3.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG65122.1 - 6.4e-29 101.1 0.0 1.1e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65122.1 - 1.6e-18 66.5 0.0 4.1e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65122.1 - 7.5e-09 35.8 0.0 1.6e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG65122.1 - 0.00089 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease PTS_IIA PF02255.16 GBG65122.1 - 0.79 9.8 5.6 3.7 7.7 3.4 2.8 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Retrotrans_gag PF03732.17 GBG65123.1 - 0.07 13.4 0.1 0.32 11.3 0.0 2.1 2 1 0 2 2 2 0 Retrotransposon gag protein PDH PF02153.17 GBG65124.1 - 8.9e-17 60.9 0.0 1.4e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 GBG65124.1 - 1.5e-11 44.7 0.0 3.5e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GBG65124.1 - 2.7e-07 30.1 0.0 5.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GBG65124.1 - 4.1e-07 30.3 0.0 7.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 GBG65124.1 - 0.0024 18.7 0.0 0.01 16.6 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.23 GBG65124.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 GBG65124.1 - 0.021 14.5 0.0 0.07 12.8 0.0 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 GBG65124.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 GBG65124.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DNA_ligase_A_C PF04679.15 GBG65124.1 - 0.16 12.6 0.0 0.4 11.3 0.0 1.6 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region DHO_dh PF01180.21 GBG65125.1 - 9e-95 317.3 0.0 1.2e-94 316.8 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Inositol_P PF00459.25 GBG65125.1 - 1.7e-73 247.5 0.0 2.5e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family UBA_3 PF09288.10 GBG65125.1 - 0.087 12.7 1.4 2 8.3 0.1 2.8 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF659 PF04937.15 GBG65126.1 - 5.9e-16 58.7 0.0 8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) EamA PF00892.20 GBG65128.1 - 1.3e-07 31.8 3.9 1.3e-07 31.8 3.9 2.8 2 1 0 2 2 2 1 EamA-like transporter family RRM_1 PF00076.22 GBG65129.1 - 1.1e-16 60.3 0.0 1.7e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GBG65130.1 - 1.9e-16 59.7 0.0 2.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GBG65131.1 - 1.3e-16 60.1 0.0 2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AFG1_ATPase PF03969.16 GBG65132.1 - 1.1e-89 300.9 0.1 4.7e-88 295.5 0.1 2.9 1 1 0 1 1 1 1 AFG1-like ATPase AAA_22 PF13401.6 GBG65132.1 - 0.0017 18.7 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG65132.1 - 0.012 16.0 0.1 0.15 12.5 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 GBG65132.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2045 PF09741.9 GBG65134.1 - 3.4e-62 209.9 0.0 7.2e-62 208.8 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2045) Fucokinase PF07959.12 GBG65135.1 - 0.12 11.3 0.1 0.16 10.9 0.1 1.4 1 1 0 1 1 1 0 L-fucokinase Alba PF01918.21 GBG65136.1 - 1.3e-22 79.4 1.1 2.1e-22 78.7 1.1 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 GBG65136.1 - 7.6e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P GARS_A PF01071.19 GBG65136.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ceramidase PF05875.12 GBG65137.1 - 3.8e-61 206.8 12.2 4.6e-61 206.6 12.2 1.0 1 0 0 1 1 1 1 Ceramidase DUF4383 PF14325.6 GBG65137.1 - 0.17 12.1 3.3 0.55 10.5 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4383) DUF1129 PF06570.11 GBG65137.1 - 0.28 10.6 4.2 5.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2157 PF09925.9 GBG65137.1 - 1.6 8.5 6.6 0.66 9.8 2.0 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Kinesin PF00225.23 GBG65138.1 - 5.7e-89 298.3 0.0 8.1e-89 297.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG65138.1 - 1e-12 48.2 0.0 2.6e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding SAM_1 PF00536.30 GBG65138.1 - 9.1e-06 26.0 0.0 1.8e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GBG65138.1 - 0.0017 18.4 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RVT_1 PF00078.27 GBG65139.1 - 2e-30 106.0 0.1 3.9e-30 105.0 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG65139.1 - 0.0082 15.9 0.1 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG65139.1 - 0.12 12.7 0.9 0.86 9.9 0.1 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein Histone PF00125.24 GBG65140.1 - 3.1e-17 63.1 0.3 9.1e-17 61.6 0.1 1.9 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 XRN_M PF17846.1 GBG65141.1 - 0.14 11.1 8.2 0.2 10.5 8.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain AAA_23 PF13476.6 GBG65141.1 - 0.2 12.2 10.0 0.3 11.6 10.0 1.3 1 0 0 1 1 1 0 AAA domain Red1 PF07964.11 GBG65141.1 - 0.38 9.0 10.3 0.5 8.6 10.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 DUF2362 PF10154.9 GBG65141.1 - 1.3 7.9 8.7 1.7 7.5 8.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) V_ATPase_I PF01496.19 GBG65141.1 - 1.3 6.8 4.9 1.6 6.6 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AIF_C PF14721.6 GBG65141.1 - 7.7 6.9 9.7 2.4 8.5 6.6 1.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1682 PF07946.14 GBG65141.1 - 7.7 5.6 27.3 11 5.1 27.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDE_Tnp_4 PF13359.6 GBG65142.1 - 1.4e-17 63.9 0.0 2.3e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65142.1 - 1.7e-09 37.6 0.0 3.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Inhibitor_I36 PF03995.13 GBG65142.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor family I36 WD40 PF00400.32 GBG65144.1 - 8e-57 187.9 26.1 1.6e-09 38.2 0.2 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG65144.1 - 7.8e-24 83.8 0.9 0.00024 21.3 0.0 6.3 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG65144.1 - 3.4e-10 39.8 0.0 0.0002 20.8 0.0 3.2 2 1 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 GBG65144.1 - 7.4e-07 29.2 0.0 0.015 15.2 0.0 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GBG65144.1 - 2.5e-06 26.7 1.0 1.3 7.9 0.0 4.2 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 GBG65144.1 - 0.0011 17.4 0.0 2.2 6.5 0.0 3.1 2 1 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 GBG65144.1 - 0.0028 18.1 9.1 5.9 7.5 0.1 5.9 5 2 1 6 6 6 1 PQQ-like domain Nup160 PF11715.8 GBG65144.1 - 0.018 13.7 0.2 16 4.0 0.0 3.7 2 1 2 4 4 4 0 Nucleoporin Nup120/160 ELYS-bb PF16687.5 GBG65144.1 - 0.031 12.9 0.0 0.092 11.3 0.0 1.8 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Nbas_N PF15492.6 GBG65144.1 - 0.045 13.1 0.2 1.9 7.7 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PP-binding PF00550.25 GBG65145.1 - 5.7e-10 39.4 0.1 8.7e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GBG65145.1 - 0.0073 16.5 0.2 0.014 15.6 0.2 1.4 1 1 0 1 1 1 1 Acyl-carrier LETM1 PF07766.13 GBG65146.1 - 7.3e-16 58.3 1.0 9.1e-16 58.0 0.0 1.6 2 0 0 2 2 2 1 LETM1-like protein RT_RNaseH_2 PF17919.1 GBG65147.1 - 7.7e-26 90.1 0.0 1.3e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65147.1 - 8e-23 80.7 0.0 1.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65147.1 - 8.8e-08 31.9 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myc_N PF01056.18 GBG65147.1 - 0.16 11.8 5.4 0.36 10.7 5.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.16 GBG65147.1 - 0.44 9.7 3.3 0.79 8.9 3.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 GBG65147.1 - 0.6 8.2 7.3 0.92 7.6 7.3 1.2 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 GBG65147.1 - 0.85 9.3 9.1 0.12 12.0 3.6 2.0 2 0 0 2 2 2 0 FAM176 family CAP_N PF01213.19 GBG65147.1 - 3.5 7.0 6.1 7.6 5.9 6.1 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SDA1 PF05285.12 GBG65147.1 - 6.1 6.2 14.4 0.41 10.0 8.9 1.7 2 0 0 2 2 2 0 SDA1 Integrase_H2C2 PF17921.1 GBG65148.1 - 4.8e-15 55.4 0.0 1.5e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65148.1 - 9.5e-10 38.4 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG65148.1 - 1.5e-06 28.4 0.0 3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65148.1 - 0.0039 17.4 0.0 0.0087 16.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger HTH_Tnp_Tc3_1 PF11427.8 GBG65148.1 - 0.27 11.1 0.6 2.8 7.9 0.0 2.7 3 0 0 3 3 3 0 Tc3 transposase Y_phosphatase PF00102.27 GBG65149.1 - 4e-07 29.8 0.2 5.3e-07 29.4 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF5339 PF17274.2 GBG65149.1 - 0.012 16.4 0.1 0.02 15.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5339) Hydrolase_3 PF08282.12 GBG65150.1 - 0.005 16.6 4.8 0.005 16.6 4.8 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAUS-augmin3 PF14932.6 GBG65152.1 - 6.3e-17 62.0 0.2 8.8e-17 61.5 0.2 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 YvrJ PF12841.7 GBG65155.1 - 0.0028 17.2 0.1 3.5 7.2 0.0 2.6 2 0 0 2 2 2 2 YvrJ protein family RVT_1 PF00078.27 GBG65155.1 - 0.0085 15.6 0.0 0.034 13.6 0.0 2.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Caldesmon PF02029.15 GBG65155.1 - 0.066 12.0 31.4 0.3 9.8 10.7 2.2 2 0 0 2 2 2 0 Caldesmon DUF1870 PF08965.10 GBG65155.1 - 1.2 9.2 17.6 0.94 9.5 0.6 4.4 6 0 0 6 6 6 0 Domain of unknown function (DUF1870) FANCM-MHF_bd PF16783.5 GBG65155.1 - 2.6 8.1 12.1 13 5.9 2.4 3.2 2 0 0 2 2 2 0 FANCM to MHF binding domain DUF4553 PF15090.6 GBG65155.1 - 4.1 6.3 23.7 5.5 5.8 7.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4553) Amidohydro_2 PF04909.14 GBG65155.1 - 4.9 6.9 7.4 16 5.1 0.8 2.4 2 0 0 2 2 2 0 Amidohydrolase Pex14_N PF04695.13 GBG65155.1 - 5.3 7.7 21.8 14 6.4 6.8 2.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2623 PF11115.8 GBG65155.1 - 5.7 7.1 5.3 43 4.3 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2623) RVT_1 PF00078.27 GBG65156.1 - 1.4e-36 126.1 0.1 2.3e-36 125.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65156.1 - 8.7e-31 105.9 0.0 2.4e-30 104.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65156.1 - 5.6e-30 103.7 0.0 1.2e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65156.1 - 5.8e-18 64.7 0.1 1.2e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Sgf11 PF08209.11 GBG65156.1 - 3.8e-14 52.0 0.3 8.8e-14 50.8 0.3 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-H2C2 PF09337.10 GBG65156.1 - 0.011 15.9 0.0 0.036 14.3 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG65157.1 - 3.2e-35 121.7 0.4 1.2e-29 103.4 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65157.1 - 1.8e-20 72.8 0.0 4.8e-15 55.4 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65157.1 - 4.9e-10 39.6 0.0 1.3e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BSP_II PF05432.11 GBG65157.1 - 0.0041 16.9 21.9 0.0041 16.9 21.9 2.0 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) GREB1 PF15782.5 GBG65157.1 - 0.16 9.1 4.7 0.31 8.1 4.7 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp_protease_2 PF13650.6 GBG65157.1 - 0.2 12.3 0.0 0.5 11.0 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF4611 PF15387.6 GBG65157.1 - 1.5 9.1 17.2 2.6 8.3 6.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RNA_pol_3_Rpc31 PF11705.8 GBG65157.1 - 1.7 8.9 25.4 0.78 10.0 19.2 2.8 2 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 RT_RNaseH_2 PF17919.1 GBG65158.1 - 1.8e-24 85.6 0.0 4.3e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65158.1 - 1e-23 83.6 0.0 2.4e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pyridoxal_deC PF00282.19 GBG65158.1 - 5.8e-19 68.0 0.0 9.8e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GBG65158.1 - 2.9e-10 39.6 0.1 9.2e-10 38.0 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GBG65158.1 - 0.015 13.9 0.0 0.023 13.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RT_RNaseH_2 PF17919.1 GBG65159.1 - 2.7e-18 65.9 0.0 5.1e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65159.1 - 1.1e-08 34.8 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65159.1 - 3.7e-07 30.4 0.0 7.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nas2_N PF18265.1 GBG65159.1 - 0.023 14.6 0.0 0.09 12.7 0.0 1.9 2 0 0 2 2 2 0 Nas2 N_terminal domain Mito_fiss_reg PF05308.11 GBG65159.1 - 0.039 14.0 0.3 0.095 12.8 0.3 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator FeoA PF04023.14 GBG65159.1 - 0.11 12.8 0.0 0.68 10.2 0.0 2.2 2 0 0 2 2 2 0 FeoA domain CDC45 PF02724.14 GBG65159.1 - 1.2 7.3 12.5 1.9 6.7 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 GBG65159.1 - 3.7 7.5 16.0 0.98 9.4 12.9 1.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Y_phosphatase PF00102.27 GBG65160.1 - 3.8e-63 213.2 0.0 4.6e-59 199.8 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GBG65160.1 - 0.0051 16.8 0.0 0.0099 15.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 GBG65160.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.20 GBG65160.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Presenilin PF01080.17 GBG65161.1 - 9.9 4.8 7.1 11 4.6 7.1 1.0 1 0 0 1 1 1 0 Presenilin rve PF00665.26 GBG65162.1 - 3.6e-08 33.6 0.0 8.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG65162.1 - 9.3 6.5 6.6 1.1 9.5 1.4 2.2 2 0 0 2 2 2 0 Zinc knuckle UCH_1 PF13423.6 GBG65163.1 - 8.5e-81 272.0 0.0 6e-79 265.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 GBG65163.1 - 4.6e-18 66.3 0.0 6.8e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 GBG65163.1 - 9e-06 25.4 0.0 5.4e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 GBG65163.1 - 0.054 13.8 0.0 5.4 7.4 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Synaptobrevin PF00957.21 GBG65164.1 - 1.9e-32 110.9 7.5 2.5e-32 110.5 7.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GBG65164.1 - 7.6e-23 80.4 0.0 1.2e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2721 PF11026.8 GBG65164.1 - 0.00053 19.9 0.1 0.00081 19.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) LMBR1 PF04791.16 GBG65164.1 - 0.076 11.9 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Fzo_mitofusin PF04799.13 GBG65164.1 - 0.13 11.8 0.6 0.22 11.1 0.6 1.3 1 0 0 1 1 1 0 fzo-like conserved region rve PF00665.26 GBG65165.1 - 5e-05 23.5 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain FlaC_arch PF05377.11 GBG65166.1 - 0.0056 17.0 0.6 0.053 13.9 0.1 2.8 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) ParB PF08775.10 GBG65166.1 - 0.94 10.0 0.0 0.94 10.0 0.0 3.4 4 0 0 4 4 4 0 ParB family DUF2968 PF11180.8 GBG65166.1 - 6.1 6.4 16.6 0.15 11.7 7.2 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF2968) RT_RNaseH_2 PF17919.1 GBG65167.1 - 2.7e-28 97.9 0.0 5.9e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65167.1 - 2e-25 89.1 0.0 3.8e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65167.1 - 8.8e-18 64.6 0.1 2.4e-17 63.2 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG65168.1 - 0.014 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG65168.1 - 0.015 15.9 0.0 0.033 14.7 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG65169.1 - 2e-13 50.6 0.0 5e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG65169.1 - 3e-10 40.0 0.3 1.3e-09 38.1 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG65169.1 - 3.4e-08 33.9 0.0 7.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG65169.1 - 3.8e-07 29.8 0.0 9.2e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG65169.1 - 9.8e-05 22.9 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG65169.1 - 0.0099 16.2 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease CENP-K PF11802.8 GBG65169.1 - 0.017 14.7 0.1 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Centromere-associated protein K Asp_protease PF09668.10 GBG65169.1 - 0.14 11.9 0.4 0.28 11.0 0.4 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG65171.1 - 6.4e-27 93.5 0.0 1.1e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65171.1 - 8.2e-24 83.9 0.0 2e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65171.1 - 1.8e-06 27.6 0.0 3.9e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG65171.1 - 5.9e-06 26.1 2.9 1.6e-05 24.7 2.9 1.8 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG65171.1 - 0.00014 22.3 0.1 0.00032 21.2 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG65171.1 - 0.0003 20.6 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65171.1 - 0.00084 19.9 0.0 0.0022 18.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65171.1 - 0.001 18.9 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG65171.1 - 0.034 14.0 3.5 0.058 13.2 3.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG65171.1 - 0.16 12.0 0.2 5.2 7.1 0.1 2.9 3 0 0 3 3 3 0 Zinc knuckle Vfa1 PF08432.10 GBG65172.1 - 0.42 10.9 14.3 0.56 10.5 14.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Na_trans_assoc PF06512.13 GBG65172.1 - 4.7 7.4 17.1 6 7.1 17.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Asp_protease_2 PF13650.6 GBG65173.1 - 1.1e-07 32.4 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65173.1 - 5.8e-07 30.0 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG65173.1 - 1.3e-06 28.1 0.1 2e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG65173.1 - 6.3e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65173.1 - 7.2e-05 22.6 0.0 0.00017 21.3 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease TLD PF07534.16 GBG65174.1 - 2.9e-31 108.6 0.0 4.2e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 TLD SRP-alpha_N PF04086.13 GBG65174.1 - 7.7 6.3 20.0 22 4.9 20.0 1.7 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TLD PF07534.16 GBG65175.1 - 3.7e-29 101.7 0.0 9.4e-28 97.2 0.0 2.2 1 1 0 1 1 1 1 TLD TLD PF07534.16 GBG65176.1 - 4.1e-31 108.1 0.0 6e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 TLD Glyco_transf_29 PF00777.18 GBG65177.1 - 1.2e-31 110.1 0.0 2.7e-31 109.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) BET PF17035.5 GBG65178.1 - 1e-23 83.3 0.1 5e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 GBG65178.1 - 5e-20 71.4 0.0 9.9e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain OmdA PF13376.6 GBG65178.1 - 0.026 14.6 0.2 0.072 13.1 0.2 1.7 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated LPP PF04728.13 GBG65178.1 - 0.28 11.6 3.9 17 5.9 1.1 3.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 GBG65178.1 - 1.5 8.1 9.8 0.78 9.0 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) XPC-binding PF09280.11 GBG65178.1 - 2.5 7.9 6.2 4.1 7.2 0.2 3.0 2 1 0 2 2 2 0 XPC-binding domain FlaC_arch PF05377.11 GBG65178.1 - 2.7 8.4 5.0 2.8 8.4 1.5 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF659 PF04937.15 GBG65179.1 - 6.1e-10 39.2 0.2 9.5e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) E1_dh PF00676.20 GBG65180.1 - 1.6e-106 355.6 0.0 2.2e-106 355.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GBG65180.1 - 0.039 13.2 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 GBG65180.1 - 0.069 12.9 0.2 0.069 12.9 0.2 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4530 PF15039.6 GBG65180.1 - 0.15 12.2 0.0 0.69 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) DEAD PF00270.29 GBG65181.1 - 1.3e-18 67.3 0.0 2.2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG65181.1 - 2e-15 57.1 0.1 5.6e-15 55.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GBG65181.1 - 1.9e-12 47.7 7.8 6e-12 46.1 7.8 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 GBG65181.1 - 0.0034 17.4 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Nitr_red_bet_C PF14711.6 GBG65181.1 - 0.046 13.4 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal SDA1 PF05285.12 GBG65181.1 - 2.1 7.7 6.0 3.1 7.1 6.0 1.3 1 0 0 1 1 1 0 SDA1 Lung_7-TM_R PF06814.13 GBG65182.1 - 1.1e-52 179.2 13.7 1.3e-52 178.9 13.7 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 GBG65182.1 - 6.1e-06 25.8 12.3 2.8e-05 23.6 12.3 1.9 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain PIF1 PF05970.14 GBG65183.1 - 1.2e-34 120.1 0.0 1.9e-34 119.5 0.0 1.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 GBG65183.1 - 0.003 17.9 0.9 0.026 14.9 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GBG65183.1 - 0.0082 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MCC-bdg_PDZ PF10506.9 GBG65183.1 - 0.035 14.1 0.2 0.084 12.9 0.0 1.7 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Kinesin PF00225.23 GBG65183.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain Retrotrans_gag PF03732.17 GBG65184.1 - 0.032 14.5 0.0 0.089 13.1 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein RPN2_C PF18004.1 GBG65184.1 - 4.9 7.1 8.2 23 4.8 8.2 2.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Plavaka PF18759.1 GBG65185.1 - 1.9e-08 33.9 0.0 3.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase AF-4 PF05110.13 GBG65185.1 - 0.086 10.9 2.5 0.14 10.2 2.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TraI PF07057.11 GBG65186.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA helicase TraI RRM_1 PF00076.22 GBG65187.1 - 5.1e-33 112.7 0.2 6.9e-17 61.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG65187.1 - 1.9e-09 37.4 0.0 4.7e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 GBG65187.1 - 0.002 18.0 0.0 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) RRM_1 PF00076.22 GBG65188.1 - 3.6e-33 113.2 0.2 5.6e-17 61.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG65188.1 - 1.3e-09 37.9 0.0 3.9e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 GBG65188.1 - 0.0014 18.4 0.0 0.085 12.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) RRM_1 PF00076.22 GBG65189.1 - 2.9e-33 113.5 0.2 5.1e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG65189.1 - 1e-09 38.2 0.0 3.6e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 GBG65189.1 - 0.0012 18.7 0.0 0.077 12.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) PsbP PF01789.16 GBG65190.1 - 2.9e-23 82.7 0.0 4.8e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 PsbP GST_N PF02798.20 GBG65191.1 - 7.8e-16 58.2 0.0 1.8e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG65191.1 - 4.7e-12 46.0 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GBG65191.1 - 1.6e-10 41.3 0.0 3.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GBG65191.1 - 1.2e-09 38.3 0.0 2.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GBG65191.1 - 1.4e-09 37.8 0.0 3.1e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GBG65191.1 - 1.6e-05 25.1 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF659 PF04937.15 GBG65192.1 - 4.6e-30 104.5 0.1 1.5e-29 102.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65192.1 - 2.4e-05 24.0 0.0 8.6e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Vpu PF00558.19 GBG65192.1 - 1.6 8.6 0.0 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 Vpu protein SAS-6_N PF16531.5 GBG65193.1 - 4.4e-21 75.3 1.1 1e-20 74.1 0.1 2.1 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal Sas6_CC PF18594.1 GBG65193.1 - 0.0039 16.9 0.6 0.012 15.4 0.1 2.2 2 0 0 2 2 2 1 Sas6/XLF/XRCC4 coiled-coil domain FPP PF05911.11 GBG65193.1 - 0.16 10.1 47.3 3.1 5.9 6.8 3.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Filament PF00038.21 GBG65193.1 - 6.5 6.2 50.5 0.5 9.9 24.3 2.9 1 1 2 3 3 3 0 Intermediate filament protein Rep_fac_C PF08542.11 GBG65194.1 - 2.4e-16 59.9 0.1 5.1e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 GBG65194.1 - 3e-16 60.1 0.0 7.3e-16 58.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GBG65194.1 - 8e-15 55.0 0.0 2.1e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 GBG65194.1 - 8.6e-07 29.1 0.0 1.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 GBG65194.1 - 1.5e-06 28.7 0.2 0.00012 22.5 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GBG65194.1 - 1e-05 25.8 0.3 0.061 13.6 0.0 2.9 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 GBG65194.1 - 1.6e-05 24.7 0.0 5.8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 GBG65194.1 - 3e-05 24.3 0.0 8.1e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain ResIII PF04851.15 GBG65194.1 - 0.00015 21.9 0.0 0.00042 20.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 GBG65194.1 - 0.00017 21.0 0.0 0.022 14.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 GBG65194.1 - 0.00035 20.4 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 GBG65194.1 - 0.00077 19.3 0.0 0.0018 18.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain ADK PF00406.22 GBG65194.1 - 0.0028 17.8 0.6 0.23 11.5 0.0 3.1 2 1 1 3 3 3 1 Adenylate kinase PhoH PF02562.16 GBG65194.1 - 0.0029 17.1 0.1 0.25 10.8 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein AAA_5 PF07728.14 GBG65194.1 - 0.0036 17.3 0.2 0.058 13.4 0.1 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GBG65194.1 - 0.0062 16.3 0.0 0.02 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 GBG65194.1 - 0.042 13.0 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 GBG65194.1 - 0.044 13.5 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 GBG65194.1 - 0.048 14.2 0.0 0.27 11.8 0.0 2.3 2 2 0 3 3 3 0 AAA domain AAA_30 PF13604.6 GBG65194.1 - 0.06 13.1 0.1 0.38 10.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 GBG65194.1 - 0.06 13.3 0.2 14 5.6 0.0 3.1 2 1 0 2 2 2 0 NACHT domain DEAD PF00270.29 GBG65194.1 - 0.064 13.0 0.1 1.8 8.3 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 GBG65194.1 - 0.077 12.6 0.1 0.34 10.4 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.6 GBG65194.1 - 0.084 13.2 0.0 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GBG65194.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GBG65194.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 GBG65194.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.26 GBG65195.1 - 7.3e-15 55.1 1.2 1.1e-14 54.5 1.2 1.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GBG65195.1 - 6.1e-07 30.6 0.1 9.3e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GBG65195.1 - 0.02 14.2 3.1 0.02 14.2 2.4 1.3 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AOC_like PF18678.1 GBG65195.1 - 0.092 12.3 0.3 0.15 11.7 0.3 1.4 1 1 0 1 1 1 0 Allene oxide cyclase barrel like domain Ribosomal_L13 PF00572.18 GBG65196.1 - 1.9e-10 41.0 0.0 9.4e-09 35.6 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 GST_N_3 PF13417.6 GBG65197.1 - 1.5e-17 63.7 0.0 2.7e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GBG65197.1 - 5.5e-17 61.9 0.1 8.3e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG65197.1 - 7.8e-15 54.9 0.0 1.6e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GBG65197.1 - 2e-05 24.7 0.0 3.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GBG65197.1 - 3.4e-05 23.8 0.2 9.4e-05 22.4 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GBG65197.1 - 0.00088 19.5 0.1 0.0054 16.9 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.25 GBG65197.1 - 0.076 13.2 0.1 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RT_RNaseH PF17917.1 GBG65198.1 - 3.8e-16 59.3 0.0 1.2e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65198.1 - 1.7e-15 56.9 0.0 4.8e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65198.1 - 3.2e-14 53.1 0.0 6.6e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG65198.1 - 5.9e-09 35.9 0.2 1.6e-07 31.3 0.1 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG65198.1 - 2.7e-08 33.5 1.2 2.7e-08 33.5 1.2 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-H2C2 PF09337.10 GBG65198.1 - 1.1e-05 25.6 0.1 2.7e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_2 PF13696.6 GBG65198.1 - 7 6.6 14.4 0.029 14.2 2.7 3.0 4 0 0 4 4 4 0 Zinc knuckle GST_N_3 PF13417.6 GBG65199.1 - 4.2e-18 65.5 0.0 7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GBG65199.1 - 3.4e-17 62.6 0.0 6.4e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG65199.1 - 4.4e-15 55.7 0.0 9.1e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GBG65199.1 - 1.1e-05 25.4 0.3 2.6e-05 24.1 0.3 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GBG65199.1 - 7.9e-05 22.8 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GBG65199.1 - 0.0029 17.8 0.1 0.0079 16.4 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.25 GBG65199.1 - 0.0037 17.5 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Pkinase_Tyr PF07714.17 GBG65200.1 - 3.6e-40 137.9 0.0 8.7e-40 136.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG65200.1 - 1.6e-38 132.6 0.0 2.6e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PRIMA1 PF16101.5 GBG65200.1 - 3.1e-05 24.0 0.2 7.9e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 TMEM154 PF15102.6 GBG65200.1 - 0.00031 20.6 0.3 0.015 15.2 0.0 2.4 2 0 0 2 2 2 1 TMEM154 protein family DUF3357 PF11837.8 GBG65200.1 - 0.018 15.5 0.1 0.018 15.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Pkinase_fungal PF17667.1 GBG65200.1 - 0.023 13.5 2.0 0.054 12.3 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase DEC-1_N PF04625.13 GBG65200.1 - 0.038 13.0 0.8 0.061 12.3 0.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region APH PF01636.23 GBG65200.1 - 0.1 12.5 0.1 0.67 9.8 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Shisa PF13908.6 GBG65200.1 - 1.5 9.0 4.0 24 5.1 0.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Retrotrans_gag PF03732.17 GBG65201.1 - 0.00039 20.6 0.8 0.0027 18.0 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein Pkinase_Tyr PF07714.17 GBG65202.1 - 2.4e-20 72.9 0.0 2.2e-19 69.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG65202.1 - 2.7e-16 59.7 0.0 1.7e-14 53.9 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain gag-asp_proteas PF13975.6 GBG65202.1 - 2.9e-06 27.8 0.1 2e-05 25.0 0.1 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65202.1 - 0.00043 20.9 0.1 0.0022 18.6 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG65202.1 - 0.005 16.6 0.1 0.013 15.3 0.1 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG65202.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease PB1-F2 PF11986.8 GBG65202.1 - 0.07 13.3 1.0 29 5.0 0.0 3.2 3 0 0 3 3 3 0 Influenza A Proapoptotic protein Kinesin PF00225.23 GBG65203.1 - 9.5e-98 327.2 0.6 1.6e-97 326.5 0.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain RVT_1 PF00078.27 GBG65203.1 - 3.9e-29 101.7 0.1 7.8e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65203.1 - 3.1e-28 97.8 2.0 5.2e-28 97.0 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Microtub_bd PF16796.5 GBG65203.1 - 1.9e-24 86.3 0.0 4.5e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding RT_RNaseH PF17917.1 GBG65203.1 - 1.9e-17 63.4 0.0 7.6e-17 61.5 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Atg14 PF10186.9 GBG65203.1 - 0.045 12.8 1.8 0.099 11.7 1.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GldM_N PF12081.8 GBG65203.1 - 0.084 13.0 3.9 0.29 11.2 3.9 1.9 1 0 0 1 1 1 0 GldM N-terminal domain A_deaminase PF00962.22 GBG65203.1 - 0.1 11.9 0.3 0.19 11.0 0.3 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase NRBF2 PF08961.10 GBG65203.1 - 0.12 11.9 3.0 0.39 10.3 3.0 1.8 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator BST2 PF16716.5 GBG65203.1 - 0.5 11.0 3.9 9 7.0 0.9 3.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 zf-C4H2 PF10146.9 GBG65203.1 - 0.66 10.2 9.0 0.6 10.4 4.6 2.5 2 0 0 2 2 2 0 Zinc finger-containing protein Nmad5 PF18757.1 GBG65203.1 - 0.96 9.6 5.7 1.4 9.1 2.0 2.7 2 1 0 2 2 2 0 Nucleotide modification associated domain 5 Nefa_Nip30_N PF10187.9 GBG65203.1 - 0.99 9.8 7.3 22 5.4 7.1 2.9 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Fez1 PF06818.15 GBG65203.1 - 1.4 9.3 14.9 0.96 9.9 5.3 2.7 2 0 0 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 GBG65203.1 - 4.1 7.4 14.8 0.23 11.5 6.6 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med9 PF07544.13 GBG65203.1 - 6 7.0 6.4 3.1 7.9 1.4 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 RT_RNaseH PF17917.1 GBG65205.1 - 3.2e-20 72.4 0.0 5.8e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65205.1 - 8.5e-20 70.7 0.0 1.5e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65205.1 - 7.6e-12 45.2 0.7 2.8e-11 43.3 0.7 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG65205.1 - 3.4e-09 36.9 0.0 8.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG65205.1 - 2.6e-06 27.1 0.0 4.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG65206.1 - 9.3e-06 25.5 3.1 1.9e-05 24.5 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG65206.1 - 0.00061 19.6 2.7 0.0011 18.7 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF4407 PF14362.6 GBG65206.1 - 3 7.1 8.4 4.3 6.6 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Trp_syntA PF00290.20 GBG65207.1 - 4.6e-90 301.0 0.7 6e-90 300.6 0.7 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 GBG65207.1 - 2.1e-06 27.4 0.1 3.3e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 GBG65207.1 - 2.4e-05 23.8 0.5 4.1e-05 23.0 0.5 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 GBG65207.1 - 0.00011 21.5 0.1 0.00018 20.8 0.1 1.3 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase PcrB PF01884.17 GBG65207.1 - 0.0007 19.1 0.8 0.0022 17.5 0.3 1.9 2 0 0 2 2 2 1 PcrB family QRPTase_C PF01729.19 GBG65207.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF3309 PF11752.8 GBG65207.1 - 0.55 10.3 3.9 1.5 8.9 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) DnaJ-X PF14308.6 GBG65209.1 - 1.2e-37 129.4 0.0 2.2e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing EF-hand_like PF09279.11 GBG65209.1 - 0.076 13.5 0.0 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DnaJ-X PF14308.6 GBG65210.1 - 7.6e-38 130.1 0.0 1.4e-37 129.2 0.0 1.4 1 1 0 1 1 1 1 X-domain of DnaJ-containing EF-hand_like PF09279.11 GBG65210.1 - 0.04 14.4 0.2 0.21 12.1 0.0 2.1 3 0 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like Mesothelin PF06060.12 GBG65210.1 - 0.11 10.6 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) DsrH PF04077.12 GBG65211.1 - 1.7e-05 24.9 0.5 3.4 7.9 0.0 7.0 6 3 4 10 10 10 1 DsrH like protein Tcp10_C PF07202.13 GBG65211.1 - 0.0043 17.0 1.1 0.75 9.7 0.1 3.4 1 1 2 3 3 3 1 T-complex protein 10 C-terminus CsiV PF10972.8 GBG65211.1 - 0.0067 16.2 0.0 8.6 6.0 0.0 4.2 4 2 0 4 4 4 1 Peptidoglycan-binding protein, CsiV zf-NPL4 PF05020.15 GBG65211.1 - 0.14 12.3 0.0 18 5.5 0.0 3.8 2 2 3 5 5 5 0 NPL4 family, putative zinc binding region HTH_Tnp_1 PF01527.20 GBG65211.1 - 0.48 10.8 17.3 9.2 6.7 0.6 5.8 4 3 2 6 6 6 0 Transposase Pox_vIL-18BP PF05566.12 GBG65211.1 - 3.4 7.9 6.9 9 6.5 0.1 3.7 3 1 0 3 3 3 0 Orthopoxvirus interleukin 18 binding protein Sm_like PF16243.5 GBG65211.1 - 4.9 7.4 20.8 23 5.2 0.1 7.2 5 3 3 9 9 9 0 Sm_like domain Pyr_redox_2 PF07992.14 GBG65212.1 - 1.2e-07 31.3 0.0 3e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GBG65212.1 - 0.00011 22.3 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GBG65212.1 - 0.0035 17.3 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding RVT_1 PF00078.27 GBG65213.1 - 4.6e-20 72.1 0.1 1.7e-19 70.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65213.1 - 1.2e-10 41.3 0.0 3.1e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65213.1 - 0.0083 16.4 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1639 PF07797.14 GBG65214.1 - 0.11 12.4 0.1 21 5.2 0.0 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1639) Elong-fact-P_C PF09285.11 GBG65214.1 - 1.6 8.5 15.6 25 4.7 0.1 7.7 5 3 4 9 9 9 0 Elongation factor P, C-terminal Ribosomal_L27A PF00828.19 GBG65214.1 - 1.7 9.3 12.4 43 4.8 0.4 5.9 2 1 2 4 4 4 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF659 PF04937.15 GBG65215.1 - 1.4e-14 54.2 0.0 2.4e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65215.1 - 0.3 10.9 4.9 8.4 6.3 0.0 3.4 4 0 0 4 4 4 0 hAT family C-terminal dimerisation region E3_binding PF02817.17 GBG65215.1 - 4.5 7.7 5.9 17 5.8 0.3 3.2 3 0 0 3 3 3 0 e3 binding domain Pectinesterase PF01095.19 GBG65216.1 - 1.4e-55 188.1 0.1 2.3e-55 187.4 0.1 1.3 1 0 0 1 1 1 1 Pectinesterase RVT_1 PF00078.27 GBG65216.1 - 2.9e-35 121.8 0.0 5.5e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANAPC2 PF08672.11 GBG65216.1 - 0.052 14.1 0.4 0.13 12.8 0.4 1.6 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 Mg_trans_NIPA PF05653.14 GBG65217.1 - 2e-09 37.0 0.8 2e-09 37.0 0.8 2.0 2 0 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 GBG65217.1 - 1.6e-05 25.1 22.6 2e-05 24.8 3.2 3.7 3 1 1 4 4 4 2 EamA-like transporter family Multi_Drug_Res PF00893.19 GBG65217.1 - 0.0052 17.4 1.1 0.0052 17.4 1.1 2.4 3 0 0 3 3 3 1 Small Multidrug Resistance protein TMEM234 PF10639.9 GBG65217.1 - 0.28 11.2 4.0 0.26 11.4 0.3 2.3 2 0 0 2 2 2 0 Putative transmembrane family 234 GP41 PF00517.17 GBG65217.1 - 0.72 9.7 4.0 6.1 6.7 0.3 2.4 2 0 0 2 2 2 0 Retroviral envelope protein DUF2613 PF11021.8 GBG65217.1 - 4.1 7.6 9.4 3.5 7.8 4.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) RF-1 PF00472.20 GBG65218.1 - 2.8e-19 69.2 1.3 5.1e-19 68.3 1.3 1.3 1 0 0 1 1 1 1 RF-1 domain Presenilin PF01080.17 GBG65219.1 - 0.24 10.1 1.5 0.26 10.0 1.5 1.2 1 0 0 1 1 1 0 Presenilin Es2 PF09751.9 GBG65219.1 - 0.4 10.4 10.4 0.48 10.1 10.4 1.0 1 0 0 1 1 1 0 Nuclear protein Es2 Cas_DxTHG PF09455.10 GBG65219.1 - 0.94 9.0 8.4 1.2 8.6 8.4 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family COX16 PF14138.6 GBG65219.1 - 2 9.0 8.0 5.4 7.6 8.0 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 RT_RNaseH_2 PF17919.1 GBG65220.1 - 5.2e-31 106.6 0.0 1.1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65220.1 - 1.4e-24 86.4 0.0 2.8e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65220.1 - 6e-22 78.2 0.0 1.5e-18 67.2 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65220.1 - 3.7e-20 71.8 0.1 1e-19 70.4 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65220.1 - 6.8e-12 45.6 0.0 1.8e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65220.1 - 0.002 18.3 0.0 0.0072 16.5 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG65220.1 - 0.048 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG65220.1 - 0.21 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease OTU PF02338.19 GBG65221.1 - 3.2e-28 98.7 0.0 8.2e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 GBG65221.1 - 5.4e-07 29.3 0.0 0.0081 15.6 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain OmpH PF03938.14 GBG65221.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Borrelia_P83 PF05262.11 GBG65221.1 - 0.28 9.6 10.0 0.051 12.1 3.3 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein DUF2229 PF09989.9 GBG65221.1 - 4.8 6.8 5.0 2.2 7.9 1.1 2.0 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF1690 PF07956.11 GBG65221.1 - 6.1 7.3 9.3 0.8 10.1 3.0 2.1 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) RVT_1 PF00078.27 GBG65222.1 - 9.7e-28 97.2 0.0 1.6e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG65222.1 - 1.7e-11 44.3 0.1 8e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG65223.1 - 3.5e-23 81.9 0.0 7.9e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65223.1 - 2.4e-22 78.9 0.0 6.1e-22 77.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65223.1 - 4.1e-07 30.0 0.0 8.6e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG65223.1 - 7.9e-07 29.6 0.0 3.2e-06 27.6 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65223.1 - 6e-05 23.6 0.0 0.0002 21.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65223.1 - 0.00012 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65223.1 - 0.0025 17.6 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Rhamnogal_lyase PF06045.11 GBG65224.1 - 1.3e-41 142.4 0.0 1.7e-33 115.8 0.0 2.2 2 0 0 2 2 2 2 Rhamnogalacturonate lyase family CBM-like PF14683.6 GBG65224.1 - 1.5e-28 99.7 0.0 2.8e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 GBG65224.1 - 2.2e-17 62.6 0.3 8.2e-17 60.8 0.2 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II RhgB_N PF09284.10 GBG65224.1 - 0.0033 17.0 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 2 Rhamnogalacturonan lyase B, N-terminal GIY-YIG PF01541.24 GBG65225.1 - 0.0017 18.6 0.7 0.0045 17.2 0.0 2.2 2 0 0 2 2 2 1 GIY-YIG catalytic domain Rho_N PF07498.12 GBG65225.1 - 0.012 15.5 0.5 0.068 13.1 0.0 2.3 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Macoilin PF09726.9 GBG65225.1 - 7.4 5.0 19.7 13 4.2 19.7 1.4 1 0 0 1 1 1 0 Macoilin family RVT_1 PF00078.27 GBG65228.1 - 1.3e-39 136.0 0.0 2e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rhamnogal_lyase PF06045.11 GBG65229.1 - 2e-33 115.6 0.0 9.3e-32 110.2 0.0 2.1 2 0 0 2 2 2 1 Rhamnogalacturonate lyase family fn3_3 PF14686.6 GBG65229.1 - 4.6e-19 68.0 0.1 1.6e-18 66.2 0.1 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 GBG65229.1 - 4.8e-06 26.5 0.1 8.9e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III RhgB_N PF09284.10 GBG65229.1 - 0.017 14.7 0.1 0.74 9.3 0.0 2.2 2 0 0 2 2 2 0 Rhamnogalacturonan lyase B, N-terminal CarboxypepD_reg PF13620.6 GBG65229.1 - 0.048 13.9 0.1 0.45 10.8 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 GBG65229.1 - 0.064 13.4 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) DUF2428 PF10350.9 GBG65230.1 - 5.9e-68 229.1 0.0 5.9e-68 229.1 0.0 3.4 3 1 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 GBG65230.1 - 0.026 14.7 7.3 3.7 8.1 0.1 4.4 5 0 0 5 5 5 0 HEAT repeat CutA1 PF03091.15 GBG65230.1 - 0.16 11.8 0.5 5 7.1 0.0 3.0 3 0 0 3 3 3 0 CutA1 divalent ion tolerance protein CAS_CSE1 PF03378.15 GBG65232.1 - 3.4e-137 457.6 0.0 5.6e-137 456.8 0.0 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 GBG65232.1 - 1.4e-130 435.5 0.0 4.6e-130 433.7 0.0 1.9 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.19 GBG65232.1 - 1.5e-12 47.3 0.0 6e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GBG65232.1 - 6.1e-05 23.1 2.8 0.00079 19.5 0.0 3.5 3 1 2 5 5 5 1 Exportin 1-like protein Adaptin_N PF01602.20 GBG65232.1 - 0.038 12.6 1.3 2.1 6.8 0.0 3.0 3 0 0 3 3 3 0 Adaptin N terminal region Hemerythrin PF01814.23 GBG65232.1 - 0.052 14.2 0.3 0.26 11.9 0.1 2.3 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Ecm29 PF13001.7 GBG65232.1 - 0.089 11.5 0.0 17 3.9 0.1 3.1 3 0 0 3 3 3 0 Proteasome stabiliser DER1 PF04511.15 GBG65233.1 - 3.3e-46 157.6 10.9 3.9e-46 157.4 10.9 1.0 1 0 0 1 1 1 1 Der1-like family DDE_Tnp_4 PF13359.6 GBG65235.1 - 6.1e-15 55.2 0.0 1.1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65235.1 - 1.5e-05 24.7 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG65235.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG65236.1 - 2.3e-08 34.3 0.2 6.3e-08 32.9 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG65236.1 - 0.0049 17.1 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like TetR_C_15 PF17918.1 GBG65236.1 - 0.041 14.6 0.3 0.16 12.7 0.3 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Myb_DNA-bind_6 PF13921.6 GBG65236.1 - 0.16 12.2 0.7 0.37 11.1 0.7 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF659 PF04937.15 GBG65239.1 - 6.9e-15 55.2 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65239.1 - 0.0057 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Clat_adaptor_s PF01217.20 GBG65241.1 - 1.6e-53 180.5 4.8 2.4e-53 179.9 4.8 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DDE_Tnp_4 PF13359.6 GBG65241.1 - 8.7e-15 54.7 0.0 3.1e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65241.1 - 3.2e-06 26.9 0.0 8.5e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG65241.1 - 0.035 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain HA2 PF04408.23 GBG65242.1 - 8.1e-23 80.8 0.8 2.1e-22 79.4 0.0 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GBG65242.1 - 2.1e-15 56.8 0.0 4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GBG65242.1 - 2.4e-10 40.7 0.0 5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GBG65242.1 - 3.8e-06 27.2 0.1 2.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 GBG65242.1 - 1.1e-05 25.3 0.5 3.1e-05 23.8 0.5 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 GBG65242.1 - 0.0012 19.2 0.2 0.023 15.0 0.2 2.6 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 GBG65242.1 - 0.0019 17.3 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 GBG65242.1 - 0.0036 17.0 2.6 0.023 14.4 2.6 2.1 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 GBG65242.1 - 0.012 15.3 0.2 0.35 10.4 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Flavi_DEAD PF07652.14 GBG65242.1 - 0.016 15.2 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_23 PF13476.6 GBG65242.1 - 0.019 15.5 0.3 0.14 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GBG65242.1 - 0.02 15.4 0.1 0.061 13.8 0.1 1.9 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 GBG65242.1 - 0.026 13.9 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.9 GBG65242.1 - 0.03 13.6 0.0 0.08 12.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GTP_EFTU PF00009.27 GBG65242.1 - 0.088 12.3 0.2 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 GBG65242.1 - 0.16 11.7 0.1 0.47 10.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 GBG65242.1 - 0.24 10.9 0.0 0.43 10.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein LdpA_C PF12617.8 GBG65243.1 - 7.7e-59 198.4 0.2 5.8e-56 189.0 0.0 2.1 2 0 0 2 2 2 2 Iron-Sulfur binding protein C terminal Fer4_7 PF12838.7 GBG65243.1 - 1.3e-07 32.1 6.9 0.00026 21.5 0.1 2.7 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 GBG65243.1 - 5.1e-06 26.3 21.4 0.00054 19.9 4.1 2.8 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 GBG65243.1 - 2.2e-05 25.3 5.5 0.00015 22.6 6.2 2.0 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 GBG65243.1 - 3.4e-05 23.9 7.6 0.00016 21.8 6.0 2.7 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4 PF00037.27 GBG65243.1 - 4.4e-05 23.1 3.9 4.4e-05 23.1 3.9 2.9 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_10 PF13237.6 GBG65243.1 - 0.00047 20.2 6.9 0.017 15.3 0.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 GBG65243.1 - 0.001 19.4 0.4 0.042 14.3 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 GBG65243.1 - 0.0013 19.3 3.3 0.0041 17.6 3.3 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 GBG65243.1 - 0.0075 16.4 0.4 0.0075 16.4 0.4 2.7 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 GBG65243.1 - 0.011 16.2 4.4 0.011 16.2 4.4 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_2 PF12797.7 GBG65243.1 - 0.03 14.4 3.0 0.03 14.4 3.0 2.9 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 GBG65243.1 - 0.091 13.6 0.2 0.091 13.6 0.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 GBG65243.1 - 4.2 8.5 18.7 0.44 11.6 5.7 3.0 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 GBG65243.1 - 4.5 8.1 7.1 0.63 10.8 0.1 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain DDE_Tnp_4 PF13359.6 GBG65244.1 - 9.2e-14 51.4 0.0 1.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65244.1 - 0.00039 20.1 0.0 0.0019 17.8 0.0 1.8 1 1 1 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG65244.1 - 0.022 15.1 0.1 0.081 13.3 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG65244.1 - 0.16 11.6 1.5 1.2 8.7 0.2 2.4 3 0 0 3 3 3 0 Transposase DDE domain adh_short_C2 PF13561.6 GBG65245.1 - 6.5e-51 173.1 10.0 4.5e-49 167.1 0.2 2.8 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GBG65245.1 - 1.1e-10 41.4 0.1 1.2e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Enoyl_reductase PF12241.8 GBG65245.1 - 0.00098 18.5 0.0 0.059 12.7 0.0 2.2 1 1 1 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region Integrase_H2C2 PF17921.1 GBG65246.1 - 8.8e-17 61.0 0.8 2.7e-16 59.4 0.3 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG65246.1 - 3.1e-12 46.7 0.3 1.1e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65246.1 - 4.7e-10 39.7 0.0 1.2e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG65246.1 - 6.8e-06 26.0 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG65246.1 - 0.0021 18.3 0.3 0.0056 16.9 0.3 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG65246.1 - 0.013 15.7 0.1 0.036 14.3 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger DUF4187 PF13821.6 GBG65246.1 - 0.035 13.9 1.2 0.13 12.1 1.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Hist_deacetyl PF00850.19 GBG65247.1 - 3.7e-29 102.2 0.0 6.3e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Nop14 PF04147.12 GBG65247.1 - 0.015 13.5 39.6 0.02 13.1 39.6 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG65247.1 - 0.064 11.7 38.2 0.095 11.1 38.2 1.3 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG65247.1 - 0.083 12.3 43.1 0.13 11.6 43.1 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG65247.1 - 0.12 10.7 32.8 0.17 10.2 32.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 GBG65247.1 - 0.14 10.9 13.0 0.2 10.4 13.0 1.2 1 0 0 1 1 1 0 Raftlin Zip PF02535.22 GBG65247.1 - 0.4 9.9 12.6 0.62 9.2 12.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 GBG65247.1 - 1 8.0 15.7 1.4 7.6 15.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GBG65247.1 - 2.5 6.8 21.8 3.7 6.2 21.8 1.3 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 GBG65247.1 - 4.1 6.3 12.6 5.7 5.8 12.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIIAH PF12685.7 GBG65247.1 - 4.5 7.0 20.3 7.9 6.3 20.3 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein BUD22 PF09073.10 GBG65247.1 - 7 5.9 43.3 11 5.3 43.3 1.2 1 0 0 1 1 1 0 BUD22 Methyltransf_23 PF13489.6 GBG65248.1 - 3e-17 62.9 0.0 4.6e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG65248.1 - 4.1e-17 62.6 0.1 1e-16 61.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG65248.1 - 1.3e-13 51.4 0.3 3.1e-13 50.2 0.1 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG65248.1 - 5.6e-12 45.7 0.0 9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG65248.1 - 4.4e-10 40.2 0.0 1.5e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 GBG65248.1 - 4.8e-05 22.8 0.0 7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 GBG65248.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 GBG65248.1 - 0.00068 19.7 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GBG65248.1 - 0.00076 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 GBG65248.1 - 0.013 15.1 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 GBG65248.1 - 0.013 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 GBG65248.1 - 0.016 14.1 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DEAD PF00270.29 GBG65250.1 - 5.8e-35 120.6 0.1 1.7e-34 119.1 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG65250.1 - 5.6e-32 110.4 0.1 6.1e-31 107.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG65250.1 - 3.2e-07 30.5 0.0 1.5e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GBG65250.1 - 4.4e-05 22.5 0.0 0.15 10.8 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 HEM4 PF02602.15 GBG65250.1 - 0.01 15.2 0.0 0.031 13.6 0.0 1.8 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD HIP1_clath_bdg PF16515.5 GBG65250.1 - 0.021 15.5 3.4 0.021 15.5 3.4 3.2 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 GBG65250.1 - 0.19 12.2 0.8 0.88 10.1 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 GBG65250.1 - 0.71 10.6 4.2 15 6.4 0.0 3.3 3 0 0 3 3 3 0 Occludin homology domain RAP1 PF07218.11 GBG65250.1 - 2.5 6.3 3.2 3.4 5.9 3.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DOMON PF03351.17 GBG65251.1 - 1.2e-09 38.4 0.0 2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 DOMON domain GSu_C4xC__C2xCH PF09698.10 GBG65252.1 - 0.13 13.0 6.0 3 8.7 4.6 2.1 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) DOMON PF03351.17 GBG65253.1 - 0.0012 19.0 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 DOMON domain RVT_1 PF00078.27 GBG65254.1 - 1.1e-14 54.6 0.1 1.6e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65254.1 - 2.4e-13 50.0 0.0 4.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65254.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Na_trans_assoc PF06512.13 GBG65254.1 - 0.18 12.1 14.0 0.26 11.6 14.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG65254.1 - 0.54 9.6 20.5 0.71 9.2 20.5 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG65254.1 - 9.8 4.2 24.1 13 3.8 24.1 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH PF17917.1 GBG65255.1 - 5.5e-21 74.8 0.0 3e-20 72.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65255.1 - 2.3e-20 72.5 0.0 5.6e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65255.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Prok-RING_4 PF14447.6 GBG65256.1 - 2.1e-07 30.7 6.2 2.1e-07 30.7 6.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GBG65256.1 - 1.7e-06 27.9 6.8 1.7e-06 27.9 6.8 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GBG65256.1 - 9.7e-06 25.4 8.5 9.7e-06 25.4 8.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG65256.1 - 7.9e-05 22.4 5.9 7.9e-05 22.4 5.9 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG65256.1 - 0.00034 20.6 1.4 0.00034 20.6 1.4 3.0 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GBG65256.1 - 0.00068 19.9 7.2 0.00068 19.9 7.2 3.3 3 0 0 3 3 3 1 Ring finger domain zf-TRAF PF02176.18 GBG65256.1 - 0.0007 20.2 2.0 0.013 16.1 0.9 3.8 3 1 1 4 4 3 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 GBG65256.1 - 0.0014 18.5 7.7 0.0014 18.5 7.7 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 GBG65256.1 - 0.0014 18.6 1.1 0.27 11.2 0.0 2.3 2 0 0 2 2 2 2 Seven in absentia protein family Rtf2 PF04641.12 GBG65256.1 - 0.017 14.5 0.2 0.029 13.8 0.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 GBG65256.1 - 0.025 14.8 1.8 0.025 14.8 1.8 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 GBG65256.1 - 0.032 14.0 2.7 0.13 12.1 2.7 2.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-TRAF_2 PF15965.5 GBG65256.1 - 1.4 9.5 17.8 0.79 10.2 2.2 3.6 2 1 1 3 3 3 0 TRAF-like zinc-finger zf-RING_6 PF14835.6 GBG65256.1 - 6.1 6.8 10.4 0.16 11.8 2.7 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF1857 PF08982.11 GBG65257.1 - 0.029 14.2 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) zf-CCHC PF00098.23 GBG65258.1 - 3.7e-08 33.1 2.7 7.5e-08 32.1 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG65258.1 - 0.02 14.6 0.6 0.04 13.7 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG65258.1 - 0.096 12.5 0.4 0.33 10.8 0.4 1.9 1 0 0 1 1 1 0 Zinc knuckle SOBP PF15279.6 GBG65258.1 - 3.3 8.2 11.3 5.1 7.6 11.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DOMON PF03351.17 GBG65259.1 - 8e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 DOMON domain HicB_lk_antitox PF15919.5 GBG65260.1 - 0.098 12.8 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Ribosomal_S2 PF00318.20 GBG65261.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 YccV-like PF08755.11 GBG65262.1 - 4.6e-28 97.6 0.0 7.1e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like UVR PF02151.19 GBG65262.1 - 3.3e-06 26.7 2.6 6.7e-06 25.7 2.6 1.5 1 0 0 1 1 1 1 UvrB/uvrC motif TcpS PF17456.2 GBG65262.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S gag-asp_proteas PF13975.6 GBG65263.1 - 7.5e-09 36.0 0.0 3.3e-08 34.0 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65263.1 - 4.9e-07 30.3 0.0 2.3e-06 28.2 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65263.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65263.1 - 0.008 15.9 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Trehalose_PPase PF02358.16 GBG65263.1 - 0.028 13.5 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase Topo_Zn_Ribbon PF08272.11 GBG65263.1 - 0.07 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Pyr_redox_2 PF07992.14 GBG65266.1 - 1.3e-71 241.3 6.0 2.3e-71 240.4 6.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GBG65266.1 - 2.7e-39 133.8 0.2 6.6e-39 132.6 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GBG65266.1 - 3.9e-23 81.8 5.6 3.5e-20 72.4 0.7 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG65266.1 - 5.6e-12 45.5 4.2 4.5e-09 36.0 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GBG65266.1 - 6.7e-10 38.9 2.3 1.4e-09 37.8 0.8 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG65266.1 - 4.1e-08 32.7 6.9 3.4e-06 26.4 1.3 3.2 3 1 0 4 4 4 2 FAD binding domain GIDA PF01134.22 GBG65266.1 - 1.7e-06 27.4 11.3 2.8e-05 23.4 11.3 2.5 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 GBG65266.1 - 6.8e-06 26.2 3.8 7.4e-05 22.9 0.4 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GBG65266.1 - 1.9e-05 23.5 9.2 0.00065 18.5 1.2 3.6 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 GBG65266.1 - 3.1e-05 23.4 12.6 0.011 15.0 4.7 3.4 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GBG65266.1 - 0.00021 20.6 2.6 0.00058 19.2 0.2 2.3 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 GBG65266.1 - 0.00077 19.1 4.9 0.0083 15.7 0.1 3.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.6 GBG65266.1 - 0.0064 15.7 3.7 0.03 13.5 0.3 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 GBG65266.1 - 0.0091 15.6 11.8 0.64 9.5 0.3 4.3 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GBG65266.1 - 0.016 14.5 1.2 0.016 14.5 1.2 2.9 2 1 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 GBG65266.1 - 0.024 13.7 0.6 0.75 8.8 0.1 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 GBG65266.1 - 0.044 13.7 0.2 0.044 13.7 0.2 2.8 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 GBG65266.1 - 0.057 12.7 0.5 1.2 8.3 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 GBG65266.1 - 0.16 12.4 1.6 9.9 6.7 0.1 3.3 3 0 0 3 3 3 0 Putative NAD(P)-binding Cas_DxTHG PF09455.10 GBG65268.1 - 0.0028 17.3 8.1 0.0028 17.3 8.1 3.0 1 1 2 3 3 3 1 CRISPR-associated (Cas) DxTHG family HMMR_N PF15905.5 GBG65268.1 - 0.0046 16.5 30.1 0.0046 16.5 30.1 4.7 1 1 2 4 4 4 2 Hyaluronan mediated motility receptor N-terminal Spc42p PF11544.8 GBG65268.1 - 0.044 13.8 0.1 0.044 13.8 0.1 5.1 4 1 2 6 6 6 0 Spindle pole body component Spc42p Fez1 PF06818.15 GBG65268.1 - 0.06 13.8 100.9 0.071 13.6 23.8 5.3 1 1 5 6 6 6 0 Fez1 Spc7 PF08317.11 GBG65268.1 - 0.31 9.9 113.0 0.009 14.9 22.8 6.1 1 1 6 7 7 7 0 Spc7 kinetochore protein DUF1664 PF07889.12 GBG65268.1 - 0.5 10.4 63.2 0.41 10.7 0.5 7.4 1 1 6 8 8 8 0 Protein of unknown function (DUF1664) GAS PF13851.6 GBG65268.1 - 1.8 7.9 103.5 2.2 7.6 8.0 6.6 3 1 5 8 8 8 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 GBG65268.1 - 2.3 7.0 113.9 0.077 11.9 24.6 4.5 1 1 3 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 GBG65268.1 - 9.3 6.3 115.6 0.28 11.2 17.1 7.8 1 1 7 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Palm_thioest PF02089.15 GBG65269.1 - 1.5e-69 234.6 0.0 1.8e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 GBG65269.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 GBG65269.1 - 0.24 10.9 0.0 0.38 10.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Phage_HK97_TLTM PF06120.11 GBG65270.1 - 0.027 13.7 0.1 0.043 13.0 0.1 1.3 1 0 0 1 1 1 0 Tail length tape measure protein zf-CCHC_4 PF14392.6 GBG65271.1 - 0.052 13.3 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG65271.1 - 0.065 13.3 0.5 0.13 12.4 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle EURL PF06937.11 GBG65271.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 EURL protein Cir_N PF10197.9 GBG65272.1 - 2.4e-10 40.4 1.8 2.4e-10 40.4 1.8 5.3 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 GBG65272.1 - 0.011 15.6 0.6 0.011 15.6 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle Palm_thioest PF02089.15 GBG65273.1 - 2.8e-65 220.5 0.0 3.3e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 GBG65273.1 - 0.036 13.6 0.0 0.12 11.9 0.0 1.8 2 1 0 2 2 2 0 Lipase (class 2) Integrase_H2C2 PF17921.1 GBG65274.1 - 1.4e-18 66.8 0.1 3e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG65274.1 - 3.1e-15 56.3 0.5 8.3e-15 55.0 0.5 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65274.1 - 1.7e-06 28.0 0.0 4.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65274.1 - 0.00065 19.9 0.0 0.0024 18.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG65274.1 - 0.00098 19.3 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger HU-CCDC81_bac_2 PF18175.1 GBG65274.1 - 0.0023 17.8 0.0 0.039 13.8 0.0 3.1 3 0 0 3 3 3 1 CCDC81-like prokaryotic HU domain 2 SpvB PF03534.13 GBG65274.1 - 0.23 10.6 2.1 0.32 10.2 0.1 1.9 1 1 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein CAP_N PF01213.19 GBG65276.1 - 0.17 11.4 2.2 0.39 10.1 2.2 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG65276.1 - 0.33 11.0 2.2 0.89 9.6 2.2 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 HA2 PF04408.23 GBG65277.1 - 1.5e-21 76.7 0.0 1.5e-21 76.7 0.0 3.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GBG65277.1 - 4.8e-17 62.1 0.0 9.9e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GBG65277.1 - 8.1e-11 42.3 0.0 2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GBG65277.1 - 3.3e-07 30.2 0.8 9.1e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GBG65277.1 - 4.2e-05 23.8 0.1 0.00019 21.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG65277.1 - 0.00032 20.5 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 GBG65277.1 - 0.00039 19.8 0.0 0.00039 19.8 0.0 1.7 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 GBG65277.1 - 0.0072 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 GBG65277.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GBG65277.1 - 0.02 15.2 0.1 0.045 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 GBG65277.1 - 0.021 14.8 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Microtub_bd PF16796.5 GBG65277.1 - 0.032 14.2 0.1 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 Microtubule binding AAA_7 PF12775.7 GBG65277.1 - 0.036 13.6 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 GBG65277.1 - 0.05 13.6 0.1 0.25 11.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 GBG65277.1 - 0.066 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 GBG65277.1 - 0.16 12.0 2.9 12 5.9 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 GBG65277.1 - 0.18 12.0 0.0 0.18 12.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 GBG65277.1 - 8.6 6.8 12.8 2.9 8.3 0.1 3.3 2 1 0 3 3 2 0 AAA domain Glyco_transf_90 PF05686.12 GBG65278.1 - 0.062 12.2 0.2 0.082 11.8 0.2 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 Ploopntkinase3 PF18751.1 GBG65278.1 - 0.068 13.1 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Myb_DNA-bind_4 PF13837.6 GBG65279.1 - 3.5e-08 33.7 0.2 8.7e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG65279.1 - 0.074 13.4 0.8 0.26 11.6 0.8 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RT_RNaseH_2 PF17919.1 GBG65281.1 - 4e-25 87.8 0.0 7.6e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65281.1 - 3.5e-19 69.0 0.0 7.9e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG65281.1 - 0.43 8.7 5.6 0.58 8.3 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family HTH_32 PF13565.6 GBG65281.1 - 0.94 10.1 9.9 2.8 8.6 0.0 3.9 4 1 0 4 4 4 0 Homeodomain-like domain CDC45 PF02724.14 GBG65281.1 - 1.9 6.7 7.4 2.7 6.2 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Complex1_LYR PF05347.15 GBG65283.1 - 0.11 12.6 5.9 0.26 11.4 0.1 3.0 3 0 0 3 3 3 0 Complex 1 protein (LYR family) zf-CCHC PF00098.23 GBG65284.1 - 0.043 13.9 0.3 0.043 13.9 0.3 1.9 2 0 0 2 2 2 0 Zinc knuckle ZapB PF06005.12 GBG65284.1 - 0.054 14.0 0.4 0.054 14.0 0.4 3.9 3 1 0 3 3 3 0 Cell division protein ZapB DUF1943 PF09172.11 GBG65284.1 - 0.28 10.4 6.1 0.049 12.9 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) SDA1 PF05285.12 GBG65285.1 - 0.0009 18.8 18.3 0.0012 18.3 18.3 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG65285.1 - 0.0033 15.7 17.7 0.0032 15.8 17.7 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 GBG65285.1 - 0.0086 15.5 17.6 0.012 15.0 17.6 1.3 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 GBG65285.1 - 0.017 13.5 14.3 0.021 13.1 14.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG65285.1 - 0.16 11.5 8.3 0.2 11.2 8.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAPS PF04499.15 GBG65285.1 - 0.17 10.6 5.2 0.2 10.4 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PCM1_C PF15717.5 GBG65285.1 - 0.41 9.3 15.7 0.55 8.9 15.7 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus DUF913 PF06025.12 GBG65285.1 - 0.66 8.9 2.9 0.7 8.8 2.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Merozoite_SPAM PF07133.11 GBG65285.1 - 1.1 9.3 33.8 1.9 8.5 33.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Presenilin PF01080.17 GBG65285.1 - 1.2 7.8 9.1 1.6 7.4 9.1 1.3 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 GBG65285.1 - 1.8 7.3 8.8 2.7 6.6 8.8 1.2 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.7 GBG65285.1 - 2 6.4 5.6 2.1 6.4 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LAP1C PF05609.12 GBG65285.1 - 2.1 7.3 11.6 3.6 6.6 11.6 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) YL1 PF05764.13 GBG65285.1 - 2.4 8.2 30.6 0.023 14.8 23.1 1.4 2 0 0 2 2 1 0 YL1 nuclear protein SIR4_SID PF16991.5 GBG65285.1 - 3 7.9 9.1 6.4 6.8 9.1 1.4 1 0 0 1 1 1 0 Sir4 SID domain V_ATPase_I PF01496.19 GBG65285.1 - 4.1 5.2 4.9 4.9 4.9 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Smg8_Smg9 PF10220.9 GBG65285.1 - 5.8 5.1 5.8 6.8 4.9 5.8 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Myb_DNA-bind_4 PF13837.6 GBG65288.1 - 1.4e-08 34.9 2.0 4e-08 33.5 0.9 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG65288.1 - 1.6e-05 25.2 3.0 0.00017 21.9 1.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG65288.1 - 0.00087 19.3 0.3 0.0019 18.2 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG65289.1 - 9e-08 32.4 2.2 1.5e-07 31.7 0.9 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG65289.1 - 7.8e-05 22.9 2.6 0.00052 20.3 1.0 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG65289.1 - 0.0029 17.6 0.3 0.0063 16.6 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HLH PF00010.26 GBG65290.1 - 9.3e-09 35.1 1.3 2.3e-08 33.9 1.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RT_RNaseH_2 PF17919.1 GBG65291.1 - 3.9e-50 168.0 0.0 6.9e-27 93.4 0.0 2.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65291.1 - 1.1e-28 99.6 0.0 1e-15 57.9 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65291.1 - 0.0097 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4375 PF14300.6 GBG65291.1 - 4.5 7.6 8.5 16 5.8 8.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) DUF743 PF05332.11 GBG65292.1 - 0.83 9.7 5.0 0.95 9.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF743) RVT_1 PF00078.27 GBG65293.1 - 4e-25 88.6 0.1 7.2e-25 87.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG65293.1 - 5.9e-18 65.2 0.0 1.2e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG65293.1 - 3.8e-14 52.5 0.0 2e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG65293.1 - 6.8e-13 48.8 0.0 1.6e-10 41.2 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG65293.1 - 0.068 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG65293.1 - 0.22 11.8 0.3 0.78 10.1 0.1 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase FoP_duplication PF13865.6 GBG65294.1 - 6.7 7.3 7.2 10 6.8 7.2 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-CCHC PF00098.23 GBG65295.1 - 0.063 13.4 1.2 0.12 12.5 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.29 GBG65297.1 - 1.5e-42 145.3 0.2 2.8e-42 144.5 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG65297.1 - 4.7e-32 110.6 0.0 3.1e-31 108.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG65297.1 - 7.3e-05 22.8 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GBG65297.1 - 0.00012 21.9 0.1 0.00018 21.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG65297.1 - 0.00024 21.4 0.1 0.0016 18.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GBG65297.1 - 0.006 17.0 0.0 0.018 15.5 0.0 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 GBG65297.1 - 0.026 14.4 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Helicase TniB PF05621.11 GBG65297.1 - 0.086 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Glutaredoxin PF00462.24 GBG65298.1 - 8.5e-19 67.5 0.0 1.6e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 GBG65298.1 - 0.015 15.7 0.1 0.034 14.6 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 GBG65298.1 - 0.029 14.5 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin GST_N_2 PF13409.6 GBG65298.1 - 0.031 14.6 0.1 0.091 13.1 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.6 GBG65298.1 - 0.049 13.4 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.6 GBG65298.1 - 0.049 14.0 0.0 0.078 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.20 GBG65298.1 - 0.079 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin UBX PF00789.20 GBG65299.1 - 1.7e-17 63.4 0.0 3e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain UIM PF02809.20 GBG65299.1 - 0.0067 16.3 8.4 0.017 15.0 1.3 3.7 3 0 0 3 3 3 2 Ubiquitin interaction motif UBA_4 PF14555.6 GBG65299.1 - 0.013 15.3 0.8 0.029 14.2 0.3 1.8 2 0 0 2 2 2 0 UBA-like domain MgtE PF01769.16 GBG65300.1 - 2.7e-19 69.8 6.9 4.9e-19 68.9 6.9 1.4 1 0 0 1 1 1 1 Divalent cation transporter Na_H_Exchanger PF00999.21 GBG65300.1 - 0.0053 15.6 4.8 0.0084 14.9 4.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_60s PF00428.19 GBG65300.1 - 0.0072 16.9 5.4 0.027 15.1 5.4 2.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4611 PF15387.6 GBG65300.1 - 3.1 8.1 12.2 9.8 6.5 5.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SecA_DEAD PF07517.14 GBG65301.1 - 1.4e-118 395.4 0.2 2.2e-118 394.8 0.2 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 GBG65301.1 - 1.2e-39 136.4 0.0 6.1e-39 134.1 0.0 2.2 1 1 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 GBG65301.1 - 2.2e-29 102.3 0.1 4.6e-29 101.3 0.1 1.6 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 GBG65301.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG65301.1 - 0.056 13.8 0.0 11 6.5 0.0 2.9 3 0 0 3 3 3 0 Helicase conserved C-terminal domain DUF883 PF05957.13 GBG65303.1 - 0.058 14.0 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ECH_1 PF00378.20 GBG65304.1 - 3.7e-43 147.7 0.1 6e-43 147.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GBG65304.1 - 1.8e-28 100.0 0.1 2.2e-28 99.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SDH_beta PF03315.15 GBG65304.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 Serine dehydratase beta chain Halo_GVPC PF05465.13 GBG65304.1 - 1.2 9.5 3.7 6.1 7.2 0.4 2.5 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat RVT_1 PF00078.27 GBG65305.1 - 4.9e-30 104.7 0.0 8.2e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65305.1 - 1.1e-28 99.2 0.0 4.7e-16 58.6 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65305.1 - 1.3e-27 96.1 0.0 3.2e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65305.1 - 5.5e-16 58.4 0.1 2.2e-15 56.5 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG65305.1 - 0.00024 21.3 0.0 0.00059 20.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG65305.1 - 0.0065 17.1 0.0 0.023 15.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH PF17917.1 GBG65306.1 - 3.9e-25 88.2 0.0 1.2e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65306.1 - 2.2e-23 82.2 0.0 6.3e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65306.1 - 1.5e-18 66.6 0.1 3.4e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65306.1 - 3.8e-11 42.9 3.7 1.6e-08 34.4 0.1 3.5 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG65306.1 - 1.5e-06 28.7 0.0 3.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65306.1 - 3.6e-06 26.8 0.0 6.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG65306.1 - 2e-05 24.8 0.2 7.5e-05 22.9 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain gag-asp_proteas PF13975.6 GBG65306.1 - 0.00019 21.9 0.0 0.00046 20.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Ist1 PF03398.14 GBG65306.1 - 0.025 14.5 0.2 0.049 13.5 0.2 1.4 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Asp_protease PF09668.10 GBG65306.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Ist1 PF03398.14 GBG65307.1 - 0.0017 18.3 0.2 0.0036 17.3 0.2 1.4 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RVT_1 PF00078.27 GBG65307.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_S7e PF01251.18 GBG65308.1 - 0.066 13.0 0.4 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein S7e DUF1664 PF07889.12 GBG65308.1 - 0.076 13.1 4.8 1 9.4 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) IreB PF06135.12 GBG65308.1 - 0.14 12.3 0.4 4.5 7.5 0.1 2.4 2 0 0 2 2 2 0 IreB regulatory phosphoprotein TolA_bind_tri PF16331.5 GBG65308.1 - 8 6.6 7.3 8.8 6.5 0.1 3.7 5 0 0 5 5 5 0 TolA binding protein trimerisation Tex_N PF09371.10 GBG65309.1 - 0.036 13.7 0.5 0.22 11.2 0.1 2.1 2 0 0 2 2 2 0 Tex-like protein N-terminal domain DUF1664 PF07889.12 GBG65309.1 - 0.043 13.8 3.5 0.89 9.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_S7e PF01251.18 GBG65309.1 - 0.064 13.0 0.4 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Ribosomal protein S7e TolA_bind_tri PF16331.5 GBG65309.1 - 3.6 7.7 6.3 7.5 6.7 0.1 3.8 5 0 0 5 5 5 0 TolA binding protein trimerisation Chloroa_b-bind PF00504.21 GBG65310.1 - 1.1e-48 165.8 0.0 1.5e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RT_RNaseH PF17917.1 GBG65311.1 - 2e-19 69.8 0.0 3.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65311.1 - 3.2e-19 68.8 0.0 6.5e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65311.1 - 1.7e-15 56.9 0.0 8.7e-15 54.6 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65311.1 - 3.7e-08 33.2 0.0 6.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG65311.1 - 7e-05 23.3 0.6 0.00024 21.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65311.1 - 0.00027 21.5 0.3 0.0013 19.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.10 GBG65311.1 - 0.0049 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG65311.1 - 0.27 11.0 1.0 0.54 10.1 1.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG65312.1 - 6.4e-09 35.8 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Birna_RdRp PF04197.12 GBG65312.1 - 0.011 14.1 0.1 0.026 12.9 0.0 1.5 2 0 0 2 2 2 0 Birnavirus RNA dependent RNA polymerase (VP1) SDA1 PF05285.12 GBG65313.1 - 0.01 15.3 17.3 0.011 15.1 17.3 1.0 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG65313.1 - 0.012 14.4 4.0 0.011 14.5 4.0 1.1 1 0 0 1 1 1 0 Presenilin Na_trans_assoc PF06512.13 GBG65313.1 - 0.02 15.2 11.4 0.022 15.1 11.4 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated V_ATPase_I PF01496.19 GBG65313.1 - 0.027 12.4 3.8 0.032 12.2 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Merozoite_SPAM PF07133.11 GBG65313.1 - 0.062 13.3 22.5 0.074 13.0 22.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2457 PF10446.9 GBG65313.1 - 0.1 11.8 17.7 0.13 11.4 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 GBG65313.1 - 0.1 10.9 16.9 0.12 10.7 16.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG65313.1 - 0.18 10.0 19.1 0.2 9.8 19.1 1.0 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.6 GBG65313.1 - 0.31 10.9 12.7 0.43 10.5 12.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CCDC106 PF15794.5 GBG65313.1 - 0.58 9.8 9.0 0.75 9.5 9.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Raftlin PF15250.6 GBG65313.1 - 0.59 8.8 6.2 0.62 8.8 6.2 1.0 1 0 0 1 1 1 0 Raftlin Mem_trans PF03547.18 GBG65313.1 - 0.84 8.0 1.8 0.83 8.0 1.8 1.1 1 0 0 1 1 1 0 Membrane transport protein O-antigen_lig PF13425.6 GBG65313.1 - 1.2 7.9 1.9 1.3 7.7 1.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RR_TM4-6 PF06459.12 GBG65313.1 - 1.6 8.5 11.9 2 8.2 11.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Membralin PF09746.9 GBG65313.1 - 1.7 7.6 2.8 2.1 7.3 2.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein Vfa1 PF08432.10 GBG65313.1 - 1.7 8.9 11.4 2.1 8.6 11.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MCM_bind PF09739.9 GBG65313.1 - 1.8 6.9 5.6 2.1 6.7 5.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4746 PF15928.5 GBG65313.1 - 1.9 7.9 15.0 2.2 7.6 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RRN3 PF05327.11 GBG65313.1 - 2 6.9 11.4 2.4 6.6 11.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3381 PF11861.8 GBG65313.1 - 3.5 7.4 15.7 4.8 7.0 15.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Pes-10 PF07149.11 GBG65313.1 - 4.4 6.3 20.5 5.5 5.9 20.5 1.0 1 0 0 1 1 1 0 Pes-10 Hid1 PF12722.7 GBG65313.1 - 5 5.1 9.4 5.7 4.9 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 GBG65313.1 - 6 5.7 5.4 6.9 5.5 5.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 GBG65313.1 - 6.2 6.8 6.3 7.7 6.5 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_phi PF04931.13 GBG65313.1 - 7.4 4.5 21.1 8.7 4.3 21.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi SLC12 PF03522.15 GBG65313.1 - 8.9 5.2 6.5 10 5.0 6.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Trypsin_2 PF13365.6 GBG65314.1 - 4.6e-22 79.5 0.2 9.6e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GBG65314.1 - 0.0006 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin Pcc1 PF09341.10 GBG65314.1 - 0.1 12.7 0.0 0.44 10.7 0.0 2.0 1 1 0 1 1 1 0 Transcription factor Pcc1 GCFC PF07842.12 GBG65315.1 - 9.3e-78 261.6 7.5 9.3e-78 261.6 7.5 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 GBG65315.1 - 6.1e-18 65.1 10.9 6.1e-18 65.1 10.9 2.8 3 1 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.23 GBG65315.1 - 9.1e-13 47.9 6.1 2.6e-12 46.4 6.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GBG65315.1 - 6.7e-05 22.9 3.6 0.0003 20.8 3.6 2.1 1 0 0 1 1 1 1 G-patch domain CortBP2 PF09727.9 GBG65315.1 - 0.24 11.3 7.2 0.74 9.7 7.2 1.9 1 1 0 1 1 1 0 Cortactin-binding protein-2 CorA PF01544.18 GBG65315.1 - 0.44 9.8 5.2 0.74 9.1 5.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF502 PF04367.13 GBG65316.1 - 3e-30 104.2 0.1 5.9e-30 103.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF502) DUF2417 PF10329.9 GBG65316.1 - 0.01 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Borealin PF10512.9 GBG65316.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 DUF1700 PF08006.11 GBG65316.1 - 1.8 8.0 5.1 2.9 7.4 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF502 PF04367.13 GBG65317.1 - 4.3e-30 103.7 0.1 8.2e-30 102.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF502) DUF2417 PF10329.9 GBG65317.1 - 0.015 14.8 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Borealin PF10512.9 GBG65317.1 - 0.097 12.6 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Cell division cycle-associated protein 8 DUF1700 PF08006.11 GBG65317.1 - 2.2 7.8 5.0 3.5 7.1 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF502 PF04367.13 GBG65318.1 - 2.6e-30 104.4 0.1 5.3e-30 103.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF502) DUF2417 PF10329.9 GBG65318.1 - 0.009 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Borealin PF10512.9 GBG65318.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 DUF1700 PF08006.11 GBG65318.1 - 1.7 8.1 5.1 2.6 7.5 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Proteasome PF00227.26 GBG65319.1 - 3.4e-63 212.6 0.1 5.5e-63 211.9 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 GBG65319.1 - 6.6e-09 35.3 0.7 1.8e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DnaJ PF00226.31 GBG65320.1 - 3.1e-23 81.7 0.7 8.1e-23 80.3 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain Nefa_Nip30_N PF10187.9 GBG65320.1 - 0.024 15.0 1.2 0.024 15.0 1.2 3.4 3 0 0 3 3 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF659 PF04937.15 GBG65321.1 - 2.2e-33 115.2 0.3 3.3e-33 114.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65321.1 - 0.019 14.8 0.2 0.046 13.5 0.2 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region HIT PF01230.23 GBG65322.1 - 1.1e-27 96.6 0.0 1.6e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GBG65322.1 - 2.1e-20 73.3 0.1 3e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CDH PF02611.15 GBG65322.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 CDP-diacylglycerol pyrophosphatase HIT PF01230.23 GBG65323.1 - 3.3e-28 98.3 0.0 4.1e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GBG65323.1 - 5.7e-21 75.1 0.1 7.2e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CDH PF02611.15 GBG65323.1 - 0.018 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase ANF_receptor PF01094.28 GBG65324.1 - 3.5e-16 59.3 0.0 5.7e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region TIG PF01833.24 GBG65324.1 - 2.1e-10 40.5 0.1 5.3e-06 26.4 0.2 3.3 3 0 0 3 3 3 2 IPT/TIG domain EGF PF00008.27 GBG65324.1 - 0.003 17.8 38.0 0.54 10.6 5.4 3.9 3 0 0 3 3 3 3 EGF-like domain DUF2079 PF09852.9 GBG65324.1 - 0.054 12.4 0.1 0.085 11.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) MscS_porin PF12795.7 GBG65324.1 - 0.15 11.6 5.2 0.24 10.9 5.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain RT_RNaseH_2 PF17919.1 GBG65326.1 - 1.6e-33 114.7 0.1 3.4e-33 113.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65326.1 - 5e-31 107.1 0.1 1.1e-30 106.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Arm PF00514.23 GBG65326.1 - 1.6e-24 85.1 0.7 7e-06 25.9 0.0 4.7 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat rve PF00665.26 GBG65326.1 - 1.2e-15 57.8 0.6 3.8e-15 56.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG65326.1 - 6.1e-15 55.1 0.1 1.4e-14 53.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain HEAT_EZ PF13513.6 GBG65326.1 - 8.9e-10 38.9 0.5 0.025 15.1 0.0 4.5 4 0 0 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 GBG65326.1 - 1.9e-07 31.3 0.1 0.00015 22.1 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 GBG65326.1 - 0.00033 20.7 0.2 2.1 8.8 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat Arm_2 PF04826.13 GBG65326.1 - 0.19 11.2 0.9 0.72 9.3 0.2 2.2 2 1 0 2 2 2 0 Armadillo-like TMEM247 PF15444.6 GBG65327.1 - 0.009 16.1 3.2 0.047 13.7 0.1 2.6 2 1 1 3 3 3 1 Transmembrane protein 247 Tox-URI2 PF15653.6 GBG65327.1 - 0.011 16.0 0.7 0.27 11.5 0.1 3.0 3 0 0 3 3 3 0 URI fold toxin 2 Ten1_2 PF15490.6 GBG65327.1 - 0.05 13.3 0.0 0.18 11.5 0.0 2.0 1 1 0 1 1 1 0 Telomere-capping, CST complex subunit Caudo_TAP PF02413.17 GBG65327.1 - 0.49 10.6 22.7 0.49 10.5 2.3 3.4 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK MCU PF04678.13 GBG65327.1 - 2.8 8.0 14.3 1.3 9.1 1.2 3.1 3 0 0 3 3 3 0 Mitochondrial calcium uniporter CENP-K PF11802.8 GBG65327.1 - 5.5 6.5 11.0 0.1 12.2 2.8 2.0 2 0 0 2 2 2 0 Centromere-associated protein K DUF5586 PF17824.1 GBG65327.1 - 7 5.6 9.6 1.1 8.2 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5586) SDA1 PF05285.12 GBG65328.1 - 0.00012 21.7 43.2 0.00014 21.4 43.2 1.0 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG65328.1 - 0.0012 17.3 32.1 0.0016 16.9 32.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG65328.1 - 0.0013 17.0 36.9 0.0015 16.9 36.9 1.1 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 GBG65328.1 - 0.0044 15.5 34.9 0.0062 15.0 34.9 1.4 1 0 0 1 1 1 1 Mpp10 protein TFIIF_alpha PF05793.12 GBG65328.1 - 0.034 12.8 39.3 0.049 12.2 39.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Caldesmon PF02029.15 GBG65328.1 - 0.044 12.5 42.1 0.052 12.3 42.1 1.1 1 0 0 1 1 1 0 Caldesmon Vfa1 PF08432.10 GBG65328.1 - 0.096 13.0 23.3 0.12 12.7 23.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_polI_A34 PF08208.11 GBG65328.1 - 0.2 11.7 32.5 0.32 11.1 32.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 BUD22 PF09073.10 GBG65328.1 - 0.39 10.0 37.4 0.57 9.5 37.4 1.3 1 0 0 1 1 1 0 BUD22 LTV PF04180.14 GBG65328.1 - 0.59 9.8 25.5 0.65 9.7 25.5 1.1 1 0 0 1 1 1 0 Low temperature viability protein Zip PF02535.22 GBG65328.1 - 1 8.5 13.6 1.1 8.4 13.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 GBG65328.1 - 1.6 7.7 12.9 1.8 7.5 12.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 GBG65328.1 - 2.3 7.7 26.7 2.9 7.4 26.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAPS PF04499.15 GBG65328.1 - 3.4 6.3 19.1 4.1 6.1 19.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.6 GBG65328.1 - 4.6 5.9 16.0 4.8 5.8 16.0 1.1 1 0 0 1 1 1 0 Raftlin DUF2151 PF10221.9 GBG65328.1 - 5.3 5.5 15.3 6 5.3 15.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator NPR3 PF03666.13 GBG65328.1 - 6.7 5.4 16.4 7.6 5.2 16.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4360 PF14273.6 GBG65329.1 - 6.5e-22 78.3 0.2 9.4e-22 77.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SH3_1 PF00018.28 GBG65330.1 - 4.6e-09 35.7 0.0 7.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GBG65330.1 - 6e-09 35.6 0.0 9.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GBG65330.1 - 3.3e-08 33.1 0.0 5.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain kleA_kleC PF17383.2 GBG65330.1 - 0.011 16.0 2.9 0.9 9.9 0.7 2.7 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A DUF5423 PF17461.2 GBG65331.1 - 0.053 12.4 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) PPR_2 PF13041.6 GBG65332.1 - 2.1e-111 364.0 43.3 1.1e-14 54.3 0.5 14.8 3 2 12 15 15 15 15 PPR repeat family PPR PF01535.20 GBG65332.1 - 9e-95 304.6 33.0 5.4e-08 32.6 0.1 16.3 16 0 0 16 16 16 15 PPR repeat PPR_3 PF13812.6 GBG65332.1 - 4.2e-87 286.2 3.3 8.4e-12 45.0 0.0 10.2 3 3 8 12 12 12 12 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG65332.1 - 9.8e-84 274.7 0.0 2e-09 37.0 0.0 15.3 16 0 0 16 16 15 12 PPR repeat PPR_long PF17177.4 GBG65332.1 - 1.2e-43 148.9 1.0 3.8e-14 52.6 0.0 6.0 1 1 4 5 5 5 5 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG65332.1 - 2.8e-12 47.0 0.2 0.004 17.6 0.3 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat Clathrin PF00637.20 GBG65332.1 - 8e-11 42.0 0.0 0.0062 16.4 0.0 4.9 5 1 0 5 5 5 2 Region in Clathrin and VPS MRP-S27 PF10037.9 GBG65332.1 - 8.9e-09 34.7 0.0 0.0017 17.3 0.0 4.4 2 1 2 4 4 4 2 Mitochondrial 28S ribosomal protein S27 ECSIT PF06239.11 GBG65332.1 - 1.8e-05 24.0 0.4 0.034 13.3 0.1 5.1 5 2 0 5 5 5 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.6 GBG65332.1 - 0.00011 21.9 5.6 13 6.1 0.0 7.2 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG65332.1 - 0.00015 22.3 14.6 16 6.7 0.0 9.3 8 4 4 12 12 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG65332.1 - 0.00075 19.7 0.1 0.65 10.3 0.0 4.3 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 GBG65332.1 - 0.0016 18.2 13.6 4.5 7.3 0.1 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG65332.1 - 0.0049 17.5 5.2 1.3 9.8 0.0 5.0 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG65332.1 - 0.0064 16.8 8.1 1.2 9.4 0.2 5.6 5 1 2 7 7 6 2 Tetratricopeptide repeat Vps39_1 PF10366.9 GBG65332.1 - 0.01 16.1 0.2 2.3 8.6 0.0 3.9 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 1 ATP13 PF12921.7 GBG65332.1 - 0.015 15.1 0.0 1.4 8.8 0.0 3.7 4 1 0 4 4 4 0 Mitochondrial ATPase expression Wzy_C_2 PF11846.8 GBG65332.1 - 0.015 15.2 0.0 18 5.2 0.0 3.8 4 1 1 5 5 4 0 Virulence factor membrane-bound polymerase, C-terminal BKACE PF05853.12 GBG65332.1 - 0.051 12.9 0.4 9.8 5.4 0.0 4.0 2 1 2 4 4 4 0 beta-keto acid cleavage enzyme TPR_2 PF07719.17 GBG65332.1 - 0.083 13.0 15.3 0.64 10.3 0.0 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF1884 PF08967.10 GBG65332.1 - 0.14 12.4 0.0 12 6.2 0.0 3.1 3 1 0 3 3 2 0 Domain of unknown function (DUF1884) TPR_6 PF13174.6 GBG65332.1 - 0.58 10.9 9.5 95 4.0 0.0 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG65332.1 - 0.78 10.1 8.8 0.92 9.9 0.1 4.6 6 0 0 6 6 3 0 Tetratricopeptide repeat ABC_membrane PF00664.23 GBG65334.1 - 2.2e-23 83.3 5.7 2.8e-23 83.0 5.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GBG65334.1 - 5.2e-15 56.2 0.0 1.7e-14 54.5 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GBG65334.1 - 0.00013 21.4 0.7 0.024 14.1 0.7 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GBG65334.1 - 0.00074 19.9 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 GBG65334.1 - 0.014 15.5 0.1 0.036 14.1 0.1 1.7 1 0 0 1 1 1 0 Dynamin family ATP_bind_1 PF03029.17 GBG65334.1 - 0.023 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_PrkA PF08298.11 GBG65334.1 - 0.043 12.7 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain MMR_HSR1 PF01926.23 GBG65334.1 - 0.12 12.5 0.1 0.56 10.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF659 PF04937.15 GBG65335.1 - 1.8e-76 255.2 0.0 1.2e-39 135.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65335.1 - 3.4e-07 29.9 0.2 1.4e-06 28.0 0.2 2.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Peptidase_M10_C PF08548.11 GBG65335.1 - 0.00065 19.6 0.0 1.1 9.1 0.1 2.4 2 0 0 2 2 2 2 Peptidase M10 serralysin C terminal DUF2992 PF11208.8 GBG65335.1 - 0.0012 19.1 0.0 0.24 11.6 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2992) DDE_3 PF13358.6 GBG65335.1 - 0.028 14.2 0.0 6.8 6.4 0.0 3.1 2 0 0 2 2 2 0 DDE superfamily endonuclease DUF2951 PF11166.8 GBG65335.1 - 0.035 14.3 0.9 0.77 10.0 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Corazonin PF17308.2 GBG65337.1 - 0.61 10.4 27.2 0.11 12.8 11.6 2.3 2 0 0 2 2 2 0 Pro-corazonin PRP1_N PF06424.12 GBG65337.1 - 1 9.7 14.4 0.078 13.4 3.7 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal CFIA_Pcf11 PF11526.8 GBG65337.1 - 1.4 9.4 25.4 1.8 9.1 11.1 2.2 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Presenilin PF01080.17 GBG65337.1 - 3.1 6.4 7.1 4.1 6.1 7.1 1.1 1 0 0 1 1 1 0 Presenilin Retrotrans_gag PF03732.17 GBG65338.1 - 0.014 15.6 1.2 3 8.2 0.2 2.6 1 1 1 2 2 2 0 Retrotransposon gag protein Glyco_hydro_42C PF08533.10 GBG65338.1 - 0.026 14.2 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Seryl_tRNA_N PF02403.22 GBG65338.1 - 0.032 14.5 1.5 0.067 13.4 1.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RVT_1 PF00078.27 GBG65339.1 - 2.7e-17 63.0 0.1 4.3e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65340.1 - 1.7e-22 79.7 0.1 7.5e-22 77.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65340.1 - 1.9e-21 76.0 0.0 5.5e-21 74.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65340.1 - 7.6e-19 67.6 0.0 1.6e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65340.1 - 7.6e-10 39.0 0.0 2.4e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG65340.1 - 8e-09 35.3 0.3 2.3e-08 33.9 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG65340.1 - 5.4e-07 29.5 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65340.1 - 5.2e-06 27.0 0.0 1.1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65340.1 - 9.9e-05 22.8 0.0 0.00039 20.9 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG65340.1 - 0.077 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG65340.1 - 0.094 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease BRE1 PF08647.11 GBG65340.1 - 1.1 9.4 11.3 5 7.3 5.4 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TolA_bind_tri PF16331.5 GBG65340.1 - 2.5 8.2 10.7 0.15 12.1 4.5 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation Nucleotid_trans PF03407.16 GBG65342.1 - 6.2e-36 124.4 0.0 9.4e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CDC45 PF02724.14 GBG65343.1 - 0.3 9.3 6.1 0.31 9.3 6.1 1.0 1 0 0 1 1 1 0 CDC45-like protein C2 PF00168.30 GBG65344.1 - 2.1e-16 60.1 0.1 7.8e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain Retrotrans_gag PF03732.17 GBG65344.1 - 0.00064 19.9 0.8 0.099 12.9 0.0 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein ApoB100_C PF12491.8 GBG65344.1 - 0.1 12.5 0.2 0.74 9.8 0.0 2.4 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal DUF3006 PF11213.8 GBG65344.1 - 0.27 11.5 2.0 0.66 10.2 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) C2 PF00168.30 GBG65345.1 - 2.1e-16 60.1 0.1 7.8e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain Retrotrans_gag PF03732.17 GBG65345.1 - 0.00065 19.9 0.8 0.099 12.9 0.0 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein ApoB100_C PF12491.8 GBG65345.1 - 0.11 12.5 0.2 0.74 9.8 0.0 2.4 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal DUF3006 PF11213.8 GBG65345.1 - 0.29 11.4 2.0 0.66 10.2 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Arm PF00514.23 GBG65346.1 - 1e-23 82.6 4.6 0.0002 21.3 0.0 8.7 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GBG65346.1 - 2e-05 25.0 18.1 0.099 13.2 0.1 6.8 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 GBG65346.1 - 0.002 18.4 18.1 2.7 8.5 0.2 6.2 3 1 2 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 GBG65346.1 - 0.012 16.2 0.0 1.4 9.5 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region KAP PF05804.12 GBG65346.1 - 0.023 12.8 0.0 0.087 11.0 0.0 1.9 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) HEAT PF02985.22 GBG65346.1 - 0.024 14.9 6.3 0.18 12.1 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat zf-RVT PF13966.6 GBG65347.1 - 3.8e-08 33.9 5.3 9e-08 32.7 5.3 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase CDC45 PF02724.14 GBG65349.1 - 2.1 6.5 4.3 2.8 6.1 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH PF17917.1 GBG65352.1 - 2.2e-21 76.1 0.0 5.6e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65352.1 - 2.8e-12 46.9 0.0 8.3e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG65352.1 - 5.8e-12 45.5 0.0 1.7e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65352.1 - 6.8e-11 42.1 0.8 2.3e-10 40.4 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG65352.1 - 0.0074 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Pkinase_Tyr PF07714.17 GBG65354.1 - 5.9e-16 58.5 0.1 5e-13 48.9 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG65354.1 - 1.6e-15 57.2 0.0 9.4e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain CReP_N PF10472.9 GBG65354.1 - 0.16 10.8 0.1 0.22 10.4 0.1 1.1 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor NB-ARC PF00931.22 GBG65355.1 - 6.5e-40 136.9 1.5 1.7e-38 132.3 0.0 3.1 4 0 0 4 4 4 1 NB-ARC domain LRR_8 PF13855.6 GBG65355.1 - 1.4e-13 50.3 32.3 2.4e-05 24.0 0.3 8.2 7 2 2 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 GBG65355.1 - 1e-07 32.1 33.4 0.076 13.5 0.1 9.0 4 3 3 9 9 9 7 Leucine Rich repeats (2 copies) AAA_22 PF13401.6 GBG65355.1 - 0.0015 18.8 0.0 0.0051 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG65355.1 - 0.13 12.6 0.9 0.51 10.7 0.2 2.4 2 1 0 2 2 2 0 AAA ATPase domain RVP_2 PF08284.11 GBG65356.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG65357.1 - 7e-08 32.3 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65357.1 - 8.4e-06 25.8 0.0 3.3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Sporozoite_P67 PF05642.11 GBG65357.1 - 0.00059 18.1 0.0 0.0015 16.7 0.0 1.6 1 1 1 2 2 2 1 Sporozoite P67 surface antigen RT_RNaseH PF17917.1 GBG65357.1 - 0.0048 17.2 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG65357.1 - 0.021 14.9 1.6 0.051 13.7 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_phi PF04931.13 GBG65357.1 - 9.9 4.1 5.6 15 3.5 5.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi TCP PF03634.13 GBG65359.1 - 0.2 12.2 17.3 0.23 12.0 17.3 1.2 1 0 0 1 1 1 0 TCP family transcription factor Paf1 PF03985.13 GBG65359.1 - 0.51 9.3 33.0 0.64 8.9 33.0 1.3 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 GBG65359.1 - 0.96 7.7 27.7 0.92 7.7 27.7 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.12 GBG65359.1 - 1.2 8.0 24.0 1.3 8.0 24.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 GBG65359.1 - 3.3 7.2 35.1 4.3 6.9 35.1 1.3 1 0 0 1 1 1 0 Spt20 family Endostatin PF06482.11 GBG65359.1 - 3.6 6.9 15.9 3.7 6.9 15.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Presenilin PF01080.17 GBG65359.1 - 4.4 6.0 28.9 5 5.8 28.9 1.0 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 GBG65359.1 - 4.6 5.2 21.8 4.6 5.3 21.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 GBG65359.1 - 5.1 7.1 13.1 5.5 7.0 13.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 GBG65359.1 - 6.2 6.6 27.6 8.3 6.1 27.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 GBG65359.1 - 8.3 4.7 7.6 7.7 4.8 7.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 VIT1 PF01988.19 GBG65361.1 - 7e-50 169.9 0.1 7.8e-50 169.7 0.1 1.0 1 0 0 1 1 1 1 VIT family DivIC PF04977.15 GBG65361.1 - 0.029 14.1 0.3 1.6 8.5 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4064 PF13273.6 GBG65361.1 - 0.033 14.5 2.1 1.3 9.3 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) EcoEI_R_C PF08463.10 GBG65361.1 - 0.077 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 EcoEI R protein C-terminal CCSAP PF15748.5 GBG65362.1 - 3 8.0 19.0 3.7 7.6 19.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Myb_DNA-bind_4 PF13837.6 GBG65363.1 - 2.7e-05 24.5 0.4 4.9e-05 23.6 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG65363.1 - 0.0008 19.4 0.4 0.0015 18.5 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Zip PF02535.22 GBG65363.1 - 0.0057 15.9 5.3 0.0099 15.1 5.3 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter V_ATPase_I PF01496.19 GBG65363.1 - 0.014 13.4 5.2 0.032 12.2 5.2 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 GBG65363.1 - 0.019 13.4 0.1 0.029 12.8 0.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Tmemb_9 PF05434.11 GBG65363.1 - 0.13 12.2 0.5 0.27 11.1 0.5 1.5 1 0 0 1 1 1 0 TMEM9 DUF1449 PF07290.11 GBG65363.1 - 3 7.4 6.9 5.2 6.6 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) NB-ARC PF00931.22 GBG65364.1 - 1.5e-34 119.3 0.0 2.4e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 GBG65364.1 - 0.0024 18.1 0.0 0.0074 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG65364.1 - 0.0063 16.9 0.0 0.024 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain LRR_4 PF12799.7 GBG65364.1 - 0.0074 16.7 0.9 5.9 7.5 0.0 4.0 2 2 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG65364.1 - 0.012 15.4 0.4 3.4 7.5 0.0 3.2 2 1 1 3 3 3 0 Leucine rich repeat NACHT PF05729.12 GBG65364.1 - 0.039 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain LRR_1 PF00560.33 GBG65364.1 - 0.039 14.5 0.5 3.7 8.4 0.1 3.6 2 0 0 2 2 2 0 Leucine Rich Repeat AAA_18 PF13238.6 GBG65364.1 - 0.041 14.4 0.0 0.081 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GBG65364.1 - 0.046 14.2 0.1 1.3 9.5 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 GBG65364.1 - 0.14 12.0 0.9 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 GBG65365.1 - 1.2e-31 109.8 0.0 1.6e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain LRR_4 PF12799.7 GBG65365.1 - 0.0022 18.4 0.8 1.2 9.6 0.0 4.1 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG65365.1 - 0.0054 16.5 0.4 2.5 7.9 0.1 3.2 2 1 0 3 3 3 2 Leucine rich repeat AAA_22 PF13401.6 GBG65365.1 - 0.009 16.3 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain LRR_1 PF00560.33 GBG65365.1 - 0.066 13.8 2.4 2.5 9.0 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat AAA PF00004.29 GBG65365.1 - 0.18 12.3 0.1 6.4 7.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RT_RNaseH PF17917.1 GBG65367.1 - 1.1e-16 60.9 0.0 2.8e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65367.1 - 1e-13 51.1 0.0 1.5e-12 47.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65367.1 - 2e-12 47.0 0.1 2e-12 47.0 0.1 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain DUF2514 PF10721.9 GBG65367.1 - 0.98 9.4 4.0 1.2 9.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Nop14 PF04147.12 GBG65368.1 - 0.025 12.8 9.9 0.024 12.9 9.9 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG65368.1 - 0.13 11.6 12.0 0.15 11.5 12.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG65368.1 - 0.23 9.7 12.0 0.26 9.5 12.0 1.0 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 GBG65368.1 - 1.6 8.0 16.8 2.1 7.7 16.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LAP1C PF05609.12 GBG65368.1 - 1.8 7.6 9.2 2.1 7.3 9.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SIR4_SID PF16991.5 GBG65368.1 - 1.8 8.6 5.2 2.7 8.0 5.2 1.2 1 0 0 1 1 1 0 Sir4 SID domain Plasmodium_Vir PF05795.11 GBG65368.1 - 1.9 7.8 4.9 2.4 7.5 4.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4746 PF15928.5 GBG65368.1 - 2.1 7.7 12.1 2.7 7.3 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Zip PF02535.22 GBG65368.1 - 2.1 7.5 2.8 2.1 7.5 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 GBG65368.1 - 5.4 5.0 17.6 6.3 4.8 17.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 GBG65368.1 - 5.8 6.1 20.1 6.8 5.9 20.1 1.1 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 GBG65368.1 - 6.3 5.8 9.1 7.7 5.6 9.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RR_TM4-6 PF06459.12 GBG65368.1 - 8.1 6.2 11.7 11 5.7 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 COPI_C PF06957.11 GBG65368.1 - 8.4 5.0 9.6 11 4.6 9.6 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DDE_Tnp_4 PF13359.6 GBG65369.1 - 2.5e-20 72.8 0.0 5.9e-19 68.3 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65369.1 - 2.5e-08 33.8 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein SAPS PF04499.15 GBG65370.1 - 1.1 7.9 4.5 1.3 7.7 4.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Root_cap PF06830.11 GBG65371.1 - 1.1e-07 31.9 0.1 0.00092 19.3 0.0 2.6 2 0 0 2 2 2 2 Root cap PAN_4 PF14295.6 GBG65371.1 - 4.7e-07 29.6 3.1 9.5e-07 28.6 3.1 1.5 1 0 0 1 1 1 1 PAN domain Cupin_2 PF07883.11 GBG65371.1 - 0.032 13.9 1.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Root_cap PF06830.11 GBG65373.1 - 0.041 14.0 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Root cap zf-C3HC4_2 PF13923.6 GBG65376.1 - 8.7e-13 47.9 6.7 8.7e-13 47.9 6.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG65376.1 - 3.7e-12 46.0 5.4 1.5e-11 44.1 5.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG65376.1 - 3.9e-10 39.4 6.0 3.9e-10 39.4 6.0 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG65376.1 - 6.1e-09 35.6 5.9 6.1e-09 35.6 5.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG65376.1 - 1.7e-08 34.7 8.3 1.7e-08 34.7 8.3 2.3 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG65376.1 - 4.8e-08 32.8 5.8 4.8e-08 32.8 5.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GBG65376.1 - 5.3e-08 32.9 8.5 5.3e-08 32.9 8.5 2.5 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 GBG65376.1 - 1.1e-06 28.4 5.5 2.1e-06 27.4 5.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 GBG65376.1 - 3.5e-06 26.8 7.1 9e-06 25.5 7.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 GBG65376.1 - 1.8e-05 24.5 5.6 1.8e-05 24.5 5.6 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GBG65376.1 - 9.7e-05 22.6 2.5 0.00032 20.9 2.5 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-TRAF_2 PF15965.5 GBG65376.1 - 9.7e-05 22.8 5.7 9.7e-05 22.8 5.7 2.1 1 1 1 2 2 2 1 TRAF-like zinc-finger zf-RING_11 PF17123.5 GBG65376.1 - 0.00016 21.3 6.2 0.00035 20.3 6.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 GBG65376.1 - 0.00039 20.1 5.0 0.00039 20.1 5.0 2.8 2 2 0 2 2 1 1 RING/Ubox like zinc-binding domain U-box PF04564.15 GBG65376.1 - 0.00045 20.3 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-TRAF PF02176.18 GBG65376.1 - 0.0087 16.7 3.9 0.0087 16.7 3.9 2.6 2 0 0 2 2 2 1 TRAF-type zinc finger DM PF00751.18 GBG65376.1 - 0.0092 15.9 6.3 0.052 13.5 4.2 2.7 1 1 1 2 2 2 1 DM DNA binding domain Sina PF03145.16 GBG65376.1 - 0.021 14.8 2.1 0.036 14.0 2.1 1.2 1 0 0 1 1 1 0 Seven in absentia protein family zf-UDP PF14569.6 GBG65376.1 - 0.19 11.8 5.3 0.71 10.0 5.3 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-P11 PF03854.14 GBG65376.1 - 2.7 7.7 9.3 0.59 9.8 4.1 2.3 2 0 0 2 2 2 0 P-11 zinc finger zf-C3H2C3 PF17122.5 GBG65376.1 - 2.7 8.1 7.9 8.8 6.5 7.9 1.9 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 GBG65376.1 - 3.6 7.3 10.6 0.28 10.8 5.0 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 GBG65376.1 - 7.5 6.8 13.4 0.055 13.6 4.7 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 CDC45 PF02724.14 GBG65377.1 - 1.3 7.2 25.3 1.4 7.2 25.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 GBG65377.1 - 2.8 5.9 12.5 3.2 5.7 12.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 GBG65377.1 - 3.1 5.9 32.7 3.2 5.8 32.7 1.1 1 0 0 1 1 1 0 Nop14-like family Cdh1_DBD_1 PF18196.1 GBG65377.1 - 3.2 8.1 12.5 0.52 10.6 8.6 1.7 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Mpp10 PF04006.12 GBG65377.1 - 4.2 5.7 28.8 4.4 5.6 28.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Spore_coat_CotO PF14153.6 GBG65377.1 - 5.7 6.8 19.6 6.2 6.7 19.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CSRNP_N PF16019.5 GBG65377.1 - 7.7 6.4 7.2 10 5.9 7.2 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus SpoIIIAH PF12685.7 GBG65377.1 - 9.8 5.9 17.6 11 5.7 17.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein FBPase PF00316.20 GBG65378.1 - 3.4e-42 144.1 0.4 1.6e-41 141.9 0.4 1.9 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 GBG65378.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family Myb_DNA-bind_4 PF13837.6 GBG65379.1 - 0.0032 17.8 1.3 0.034 14.5 0.4 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG65381.1 - 5.6e-15 55.4 0.9 1.7e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65381.1 - 9.7e-09 35.1 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein TrbM PF07424.11 GBG65381.1 - 0.074 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 TrbM Calici_MSP PF05752.11 GBG65383.1 - 0.04 13.7 1.3 0.047 13.5 1.3 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF5549 PF17703.1 GBG65383.1 - 2.6 7.7 7.6 3.5 7.3 7.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Branch PF02485.21 GBG65385.1 - 2.9e-60 203.8 0.0 4.5e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Myb_DNA-bind_4 PF13837.6 GBG65385.1 - 0.031 14.6 0.7 0.095 13.1 0.7 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Miga PF10265.9 GBG65385.1 - 0.44 9.5 10.7 1 8.3 10.7 1.6 1 0 0 1 1 1 0 Mitoguardin RAP1 PF07218.11 GBG65385.1 - 5.8 5.1 19.6 9.7 4.3 19.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mito_carr PF00153.27 GBG65386.1 - 1.9e-43 146.3 0.3 1.4e-17 63.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GBG65386.1 - 9.1e-05 22.8 0.0 0.00077 19.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG65386.1 - 0.0013 18.5 0.0 0.037 14.0 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GBG65386.1 - 0.013 15.0 0.0 0.043 13.4 0.0 1.9 2 0 0 2 2 2 0 EF hand SHOCT PF09851.9 GBG65386.1 - 0.19 11.5 1.6 1.7 8.5 0.1 2.8 2 0 0 2 2 2 0 Short C-terminal domain Mito_carr PF00153.27 GBG65387.1 - 6.5e-44 147.8 0.2 4.1e-17 61.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GBG65387.1 - 0.00023 21.6 0.0 0.00084 19.8 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG65387.1 - 0.0011 18.7 0.0 0.037 14.0 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GBG65387.1 - 0.014 14.9 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 2 0 EF hand Usp PF00582.26 GBG65388.1 - 3.8e-28 98.8 0.6 3.8e-28 98.8 0.6 1.6 2 0 0 2 2 2 1 Universal stress protein family TB2_DP1_HVA22 PF03134.19 GBG65390.1 - 1.9e-25 88.6 7.5 2.7e-25 88.1 7.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Bacteriocin_IIi PF11758.8 GBG65390.1 - 0.07 13.0 0.4 0.17 11.7 0.4 1.6 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin Sulf_transp PF04143.14 GBG65392.1 - 8.9e-13 48.5 29.5 4.3e-11 42.9 13.6 3.2 3 0 0 3 3 3 3 Sulphur transport Nuc_sug_transp PF04142.15 GBG65392.1 - 0.088 12.0 2.9 0.066 12.4 1.2 1.6 2 0 0 2 2 2 0 Nucleotide-sugar transporter Rab5ip PF07019.12 GBG65392.1 - 0.13 12.9 0.1 0.13 12.9 0.1 3.3 3 2 0 3 3 3 0 Rab5-interacting protein (Rab5ip) DUF3742 PF12553.8 GBG65392.1 - 9.6 6.4 8.0 1.3 9.1 1.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3742) Pacs-1 PF10254.9 GBG65393.1 - 0.025 13.6 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Na_Ca_ex PF01699.24 GBG65396.1 - 5.9e-41 139.9 27.9 3.4e-21 75.8 5.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Smg4_UPF3 PF03467.15 GBG65396.1 - 0.27 11.2 1.9 0.41 10.6 1.9 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family DUF659 PF04937.15 GBG65397.1 - 0.00024 21.0 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GCP_C_terminal PF04130.13 GBG65399.1 - 1.3e-13 51.2 0.1 1.5e-13 50.9 0.1 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal zinc_ribbon_13 PF09855.9 GBG65399.1 - 0.044 13.9 0.0 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) TBCC_N PF16752.5 GBG65399.1 - 0.18 12.3 1.3 0.25 11.8 0.3 1.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain GCP_N_terminal PF17681.1 GBG65400.1 - 4e-44 151.5 0.3 6.5e-44 150.8 0.3 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GBG65400.1 - 9.5e-15 54.8 0.5 9.5e-15 54.8 0.5 2.2 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal DDE_Tnp_4 PF13359.6 GBG65401.1 - 1.2e-23 83.5 0.0 2.1e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65401.1 - 2.6e-09 37.0 0.0 3.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG65401.1 - 0.00014 21.5 0.3 0.00049 19.8 0.0 2.0 2 0 0 2 2 2 1 Transposase DDE domain PSII_Pbs27 PF13326.6 GBG65403.1 - 4.5e-30 104.8 0.7 6.5e-30 104.3 0.7 1.2 1 0 0 1 1 1 1 Photosystem II Pbs27 GHMP_kinases_N PF00288.26 GBG65403.1 - 0.11 12.8 1.4 0.38 11.0 0.9 2.2 2 0 0 2 2 2 0 GHMP kinases N terminal domain Calmodulin_bind PF07887.11 GBG65404.1 - 1.2e-20 74.0 0.1 1.8e-20 73.4 0.1 1.2 1 0 0 1 1 1 1 Calmodulin binding protein-like Calmodulin_bind PF07887.11 GBG65406.1 - 1.7e-81 273.7 0.0 2.1e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Calmodulin binding protein-like Cupin_1 PF00190.22 GBG65407.1 - 1.2e-37 128.8 0.5 3.7e-21 75.3 0.4 3.1 3 0 0 3 3 3 3 Cupin Phage_integrase PF00589.22 GBG65408.1 - 2.4e-07 30.7 0.0 4.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.27 GBG65410.1 - 2.2e-14 53.5 0.1 3.2e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65410.1 - 0.0023 17.9 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Autophagy_N PF03986.13 GBG65410.1 - 0.041 13.8 2.0 0.068 13.1 2.0 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain PTPRCAP PF15713.5 GBG65410.1 - 0.13 12.5 11.9 0.22 11.8 11.9 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GBG65410.1 - 0.4 8.8 9.7 0.5 8.5 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG65410.1 - 2.4 6.3 10.4 3.2 5.9 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG65410.1 - 5.6 6.3 12.4 7.2 5.9 12.4 1.1 1 0 0 1 1 1 0 SDA1 Pectinesterase PF01095.19 GBG65411.1 - 3.7e-70 236.0 1.0 5e-70 235.6 1.0 1.1 1 0 0 1 1 1 1 Pectinesterase Histone PF00125.24 GBG65415.1 - 1e-12 48.6 0.2 1e-12 48.6 0.2 3.3 4 0 0 4 4 4 1 Core histone H2A/H2B/H3/H4 Cro PF09048.10 GBG65415.1 - 0.051 13.6 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Cro RT_RNaseH_2 PF17919.1 GBG65416.1 - 1.1e-16 60.7 0.0 2e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65416.1 - 2.4e-08 33.8 0.1 3.4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65416.1 - 1.9e-06 28.1 0.0 3.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG65416.1 - 0.56 8.4 10.4 0.69 8.0 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG65416.1 - 0.59 9.5 11.0 0.81 9.0 11.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG65416.1 - 0.84 7.8 11.3 1.2 7.4 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG65417.1 - 1.9e-17 63.1 0.0 3.4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65417.1 - 5.5e-09 35.9 0.1 7.8e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65417.1 - 3.7e-07 30.4 0.0 9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GDP_Man_Dehyd PF16363.5 GBG65418.1 - 3.2e-136 454.1 0.0 3.8e-136 453.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG65418.1 - 8.4e-70 235.0 0.1 1e-69 234.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GBG65418.1 - 2.5e-05 23.5 0.0 3.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GBG65418.1 - 0.00012 21.3 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 GBG65418.1 - 0.17 11.4 0.0 0.56 9.7 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family TPT PF03151.16 GBG65420.1 - 6.3e-09 35.6 15.9 8.4e-09 35.2 15.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG65420.1 - 0.0014 18.8 11.5 0.0014 18.8 11.5 3.0 3 0 0 3 3 3 1 EamA-like transporter family RunxI PF08504.11 GBG65420.1 - 1.7 9.4 5.0 2.8 8.7 0.1 3.1 2 1 1 3 3 3 0 Runx inhibition domain zf-HIT PF04438.16 GBG65421.1 - 0.00054 19.8 17.0 0.0012 18.6 17.0 1.6 1 0 0 1 1 1 1 HIT zinc finger DUF2151 PF10221.9 GBG65421.1 - 2.1 6.8 10.0 4.5 5.7 10.0 1.5 1 0 0 1 1 1 0 Cell cycle and development regulator RVT_1 PF00078.27 GBG65422.1 - 4e-15 55.9 0.0 1.1e-10 41.4 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2499 PF10693.9 GBG65422.1 - 0.00014 22.0 4.1 0.00052 20.2 4.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) RVT_1 PF00078.27 GBG65423.1 - 1.7e-26 93.1 0.2 3e-26 92.3 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65423.1 - 1.5e-24 85.9 0.0 3.3e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65423.1 - 3.8e-20 72.1 0.0 9.2e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2499 PF10693.9 GBG65423.1 - 2.4e-15 56.6 1.0 4.6e-15 55.7 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) Integrase_H2C2 PF17921.1 GBG65423.1 - 8.8e-12 45.0 0.0 2.2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65423.1 - 9e-07 29.1 0.0 5.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG65423.1 - 0.22 11.3 0.6 0.6 9.9 0.1 2.1 2 0 0 2 2 2 0 Integrase core domain LysM PF01476.20 GBG65424.1 - 1e-18 67.1 0.0 1.3e-09 38.0 0.0 2.4 2 0 0 2 2 2 2 LysM domain B3 PF02362.21 GBG65425.1 - 2.9e-11 43.1 0.0 6.5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 B3 DNA binding domain FRG2 PF15315.6 GBG65425.1 - 5.4 7.2 7.6 2 8.6 3.7 2.0 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 DUF4149 PF13664.6 GBG65427.1 - 3.2e-25 88.4 5.7 3.2e-25 88.4 5.7 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) HLH PF00010.26 GBG65430.1 - 5.2e-10 39.1 0.0 5.2e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nucleo_P87 PF07267.11 GBG65430.1 - 3.3 6.5 13.2 8.4 5.1 13.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RT_RNaseH PF17917.1 GBG65431.1 - 4.2e-13 49.5 0.1 7.2e-10 39.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65431.1 - 0.0012 18.9 0.2 0.062 13.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG65431.1 - 0.026 14.8 0.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein YqzH PF14164.6 GBG65431.1 - 0.14 12.3 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 YqzH-like protein Csm1_N PF18504.1 GBG65431.1 - 0.28 11.6 3.0 0.38 11.1 1.2 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain p450 PF00067.22 GBG65432.1 - 1.7e-55 188.6 0.0 2.9e-46 158.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Zn_peptidase PF04228.13 GBG65432.1 - 0.15 11.5 0.0 0.15 11.5 0.0 2.5 3 0 0 3 3 3 0 Putative neutral zinc metallopeptidase SPX PF03105.19 GBG65432.1 - 2 8.2 25.7 0.12 12.2 1.6 2.3 2 0 0 2 2 2 0 SPX domain Retrotrans_gag PF03732.17 GBG65433.1 - 0.0094 16.2 3.0 0.025 14.9 0.1 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein Rho_N PF07498.12 GBG65434.1 - 0.074 13.0 0.5 0.38 10.7 0.5 2.1 1 1 0 1 1 1 0 Rho termination factor, N-terminal domain Antimicrobial_5 PF08026.11 GBG65434.1 - 0.22 11.6 0.4 0.33 11.0 0.4 1.2 1 0 0 1 1 1 0 Bee antimicrobial peptide DUF659 PF04937.15 GBG65436.1 - 3.2e-33 114.8 0.1 3.2e-33 114.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65436.1 - 0.0041 16.9 0.5 0.0095 15.7 0.5 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RR_TM4-6 PF06459.12 GBG65436.1 - 0.16 11.8 28.2 0.41 10.4 28.2 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 GBG65436.1 - 2.9 6.5 15.9 4.3 6.0 15.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4588 PF15251.6 GBG65438.1 - 0.005 16.6 0.0 0.005 16.6 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4588) Auto_anti-p27 PF06677.12 GBG65438.1 - 0.16 12.1 0.4 0.32 11.2 0.4 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Spt20 PF12090.8 GBG65438.1 - 0.92 9.1 10.7 2.9 7.4 3.3 2.3 2 0 0 2 2 2 0 Spt20 family CDC45 PF02724.14 GBG65439.1 - 1.1e-05 23.9 12.2 1.5e-05 23.6 12.2 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG65439.1 - 0.0005 18.4 30.6 0.00064 18.1 30.6 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG65439.1 - 0.0036 16.8 33.2 0.0046 16.4 33.2 1.1 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 GBG65439.1 - 0.015 13.8 26.7 0.019 13.5 26.7 1.1 1 0 0 1 1 1 0 Mpp10 protein LisH_TPL PF17814.1 GBG65439.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 LisH-like dimerisation domain PDDEXK_6 PF04720.12 GBG65439.1 - 0.65 9.9 6.1 1.1 9.1 6.1 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function CPSF100_C PF13299.6 GBG65439.1 - 1.1 9.5 5.4 2.1 8.5 5.4 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RRN3 PF05327.11 GBG65439.1 - 1.3 7.5 26.7 2.2 6.7 26.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_Rpc4 PF05132.14 GBG65439.1 - 2.7 8.4 6.8 4.9 7.6 6.8 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2151 PF10221.9 GBG65439.1 - 2.8 6.4 6.1 3.8 6.0 6.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 GBG65439.1 - 3.1 6.9 4.6 4 6.6 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GBG65439.1 - 4 6.1 5.6 5.1 5.8 5.6 1.1 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 GBG65441.1 - 5.5e-27 93.5 4.6 1.6e-09 38.2 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG65441.1 - 5.1e-10 39.5 0.1 0.0019 18.5 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG65441.1 - 4.2e-07 29.6 0.0 0.00012 21.5 0.0 2.6 2 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 GBG65441.1 - 5.3e-05 22.1 0.1 0.096 11.3 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 GBG65441.1 - 0.00022 21.2 0.0 0.00027 20.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 GBG65441.1 - 0.0096 14.9 0.2 1.9 7.4 0.1 2.0 1 1 1 2 2 2 2 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 GBG65441.1 - 0.028 13.4 0.0 0.49 9.3 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PUA_3 PF17785.1 GBG65441.1 - 0.072 12.9 0.1 1.9 8.3 0.0 2.3 1 1 1 2 2 2 0 PUA-like domain CLN3 PF02487.17 GBG65441.1 - 0.081 12.0 0.1 0.096 11.7 0.1 1.1 1 0 0 1 1 1 0 CLN3 protein ASCH PF04266.14 GBG65441.1 - 0.17 12.5 0.0 1.9 9.1 0.0 2.2 2 0 0 2 2 2 0 ASCH domain zf-CCHC PF00098.23 GBG65442.1 - 0.00037 20.4 2.4 0.00091 19.2 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle HSBP1 PF06825.12 GBG65442.1 - 0.0061 16.4 0.3 0.41 10.5 0.0 2.7 2 0 0 2 2 2 1 Heat shock factor binding protein 1 zf-CCHC_4 PF14392.6 GBG65442.1 - 0.039 13.7 0.8 0.1 12.3 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle OsmC PF02566.19 GBG65442.1 - 0.19 12.2 1.5 0.46 11.0 0.3 2.3 2 0 0 2 2 2 0 OsmC-like protein SUI1 PF01253.22 GBG65443.1 - 7.4e-26 90.5 0.5 9.3e-26 90.2 0.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Abhydrolase_6 PF12697.7 GBG65444.1 - 1.3e-11 45.6 4.9 1.3e-11 45.6 4.9 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG65444.1 - 2.6e-10 40.0 1.0 1.7e-09 37.4 0.7 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG65444.1 - 8.9e-08 32.1 1.6 4.2e-07 29.9 1.6 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 GBG65444.1 - 0.19 11.8 0.6 0.32 11.1 0.6 1.3 1 0 0 1 1 1 0 Thioesterase domain RVT_1 PF00078.27 GBG65446.1 - 1.7e-12 47.3 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG65446.1 - 0.33 11.2 18.7 0.53 10.5 18.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated DUF3807 PF12720.7 GBG65446.1 - 0.45 10.8 19.2 0.13 12.5 16.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SDA1 PF05285.12 GBG65446.1 - 0.72 9.2 27.7 0.97 8.8 27.7 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG65446.1 - 2.6 7.3 25.5 3.5 6.9 25.5 1.2 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG65446.1 - 2.7 7.5 12.4 4.8 6.6 12.4 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAPS PF04499.15 GBG65446.1 - 3.7 6.2 5.7 4.1 6.1 5.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4746 PF15928.5 GBG65446.1 - 5.4 6.3 20.2 11 5.4 20.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 GBG65446.1 - 8.8 4.4 27.9 12 4.0 27.9 1.1 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_4 PF13837.6 GBG65448.1 - 9.1e-11 42.0 0.5 9.1e-11 42.0 0.5 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG65448.1 - 0.00068 19.9 0.0 0.0026 18.0 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Conotoxin PF02950.17 GBG65448.1 - 0.073 14.1 0.8 0.27 12.3 0.0 2.4 2 0 0 2 2 2 0 Conotoxin Myb_DNA-bind_5 PF13873.6 GBG65448.1 - 0.1 12.7 1.1 0.34 11.0 1.1 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain GRP PF07172.11 GBG65448.1 - 5.6 7.7 15.9 4.8 7.9 0.3 4.1 4 0 0 4 4 4 0 Glycine rich protein family DDE_Tnp_4 PF13359.6 GBG65449.1 - 7.5e-30 103.7 0.0 1.2e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65449.1 - 6.7e-14 52.0 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG65449.1 - 0.00053 19.7 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain cobW PF02492.19 GBG65451.1 - 2.9e-56 189.8 1.4 4.7e-56 189.2 1.4 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GBG65451.1 - 4.7e-22 77.7 0.0 1.1e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GBG65451.1 - 6e-05 23.0 0.1 0.19 11.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GBG65451.1 - 0.00057 19.5 0.7 0.24 10.9 0.1 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MobB PF03205.14 GBG65451.1 - 0.0067 16.3 0.1 0.0067 16.3 0.1 2.4 3 0 0 3 3 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2052 PF09747.9 GBG65451.1 - 0.0096 16.1 14.6 0.012 15.8 4.3 2.2 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) AAA_23 PF13476.6 GBG65451.1 - 0.014 16.0 0.8 0.014 16.0 0.8 3.1 2 1 1 3 3 2 0 AAA domain FYDLN_acid PF09538.10 GBG65451.1 - 0.014 16.0 1.4 0.014 16.0 1.4 2.8 2 1 0 2 2 1 0 Protein of unknown function (FYDLN_acid) CENP-B_dimeris PF09026.10 GBG65451.1 - 0.016 15.6 12.0 0.034 14.5 0.9 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain AAA_29 PF13555.6 GBG65451.1 - 0.026 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FancD2 PF14631.6 GBG65451.1 - 0.03 11.8 6.4 0.062 10.7 0.1 2.0 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease MMR_HSR1 PF01926.23 GBG65451.1 - 0.03 14.4 0.4 0.25 11.5 0.4 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 GBG65451.1 - 0.032 13.3 0.1 0.057 12.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 GBG65451.1 - 0.032 13.9 0.1 0.081 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Myc_N PF01056.18 GBG65451.1 - 0.037 13.9 0.4 0.037 13.9 0.4 1.9 2 0 0 2 2 2 0 Myc amino-terminal region ATPase_2 PF01637.18 GBG65451.1 - 0.038 13.9 1.2 0.07 13.0 0.4 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea CNDH2_C PF16858.5 GBG65451.1 - 0.058 13.3 7.2 1.6 8.6 0.4 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term AAA_16 PF13191.6 GBG65451.1 - 0.06 13.7 3.1 0.092 13.1 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GBG65451.1 - 0.12 12.6 0.0 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Spore_coat_CotO PF14153.6 GBG65451.1 - 0.14 12.1 13.5 1.8 8.5 0.3 2.2 2 0 0 2 2 2 0 Spore coat protein CotO ABC_tran PF00005.27 GBG65451.1 - 0.14 12.7 0.9 0.32 11.5 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Plasmodium_Vir PF05795.11 GBG65451.1 - 0.19 11.1 5.6 3 7.2 0.9 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein AAA_18 PF13238.6 GBG65451.1 - 0.25 11.9 0.1 0.25 11.9 0.1 2.7 2 0 0 2 2 1 0 AAA domain Mpp10 PF04006.12 GBG65451.1 - 0.49 8.8 18.6 0.79 8.1 2.9 2.1 2 0 0 2 2 2 0 Mpp10 protein Presenilin PF01080.17 GBG65451.1 - 4 6.1 9.3 2.3 6.9 1.3 2.1 2 0 0 2 2 2 0 Presenilin Peptidase_S49_N PF08496.10 GBG65451.1 - 6.5 6.8 7.5 0.93 9.5 0.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Zip PF02535.22 GBG65451.1 - 9.4 5.3 25.8 2.4 7.3 1.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter LON_substr_bdg PF02190.16 GBG65453.1 - 1e-23 84.3 0.0 1.3e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DUF3958 PF13125.6 GBG65453.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) SPX PF03105.19 GBG65453.1 - 1.7 8.5 4.7 0.82 9.5 2.4 1.7 2 0 0 2 2 2 0 SPX domain RT_RNaseH PF17917.1 GBG65456.1 - 1.8e-22 79.6 0.0 3.1e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65456.1 - 4.2e-22 78.1 0.0 7.1e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65456.1 - 3.3e-21 75.1 0.1 6.9e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65456.1 - 4.4e-16 59.1 0.0 6.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG65456.1 - 2.3e-10 40.7 0.1 1.4e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG65456.1 - 0.03 14.5 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger APC1_C PF18122.1 GBG65457.1 - 1.4 8.9 15.2 3.6 7.5 1.4 4.0 2 1 1 3 3 3 0 Anaphase-promoting complex sub unit 1 C-terminal domain zf-CCHC PF00098.23 GBG65461.1 - 0.0001 22.2 2.7 0.00023 21.1 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG65461.1 - 0.58 10.0 6.0 0.13 12.2 1.7 2.0 2 0 0 2 2 2 0 Zinc knuckle RmuC PF02646.16 GBG65461.1 - 5.2 6.1 11.3 5.4 6.1 6.8 2.0 1 1 1 2 2 2 0 RmuC family NPA PF16469.5 GBG65461.1 - 5.3 7.6 12.4 0.35 11.5 6.0 2.3 3 1 0 3 3 3 0 Nematode polyprotein allergen ABA-1 DUF4192 PF13830.6 GBG65461.1 - 9.7 6.1 12.3 22 5.0 12.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) Dimer_Tnp_hAT PF05699.14 GBG65462.1 - 1.4e-05 24.8 0.3 2.7e-05 23.9 0.3 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG65462.1 - 0.00071 19.5 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF45 PF01863.17 GBG65462.1 - 0.13 12.3 1.0 2.1 8.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 Ribosomal_60s PF00428.19 GBG65463.1 - 0.61 10.7 5.4 2.4 8.8 5.4 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Corazonin PF17308.2 GBG65464.1 - 0.27 11.6 17.0 1 9.7 7.7 2.6 3 0 0 3 3 3 0 Pro-corazonin BUD22 PF09073.10 GBG65464.1 - 4.5 6.5 13.0 5.7 6.2 13.0 1.1 1 0 0 1 1 1 0 BUD22 NUFIP2 PF15293.6 GBG65465.1 - 0.074 11.9 0.1 0.074 11.9 0.1 1.7 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 2 Nudix_hydro PF18290.1 GBG65465.1 - 1.1 9.3 3.2 14 5.8 0.0 2.9 3 0 0 3 3 3 0 Nudix hydrolase domain DUF4778 PF16008.5 GBG65465.1 - 1.9 8.4 9.1 3.1 7.8 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) RVT_1 PF00078.27 GBG65466.1 - 3.1e-28 98.8 0.0 4.2e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG65466.1 - 0.05 12.7 0.0 0.094 11.8 0.0 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 Imm72 PF15584.6 GBG65467.1 - 0.21 11.7 1.8 5 7.3 0.1 2.5 2 1 0 2 2 2 0 Immunity protein 72 LRR_4 PF12799.7 GBG65468.1 - 7.9e-06 26.1 5.2 0.00013 22.3 1.0 3.1 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GBG65468.1 - 0.066 12.7 2.5 0.4 10.2 2.5 1.9 1 1 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.6 GBG65468.1 - 0.22 11.3 6.5 0.87 9.4 0.2 2.9 2 1 0 2 2 2 0 Leucine rich repeat RVT_1 PF00078.27 GBG65469.1 - 1.2e-26 93.7 0.0 2.6e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG65469.1 - 7.5e-09 36.0 0.0 1.9e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65469.1 - 1.1e-08 35.6 0.0 2.9e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65469.1 - 1.4e-06 28.1 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG65469.1 - 9.9e-05 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG65469.1 - 0.022 15.0 1.4 0.05 13.9 0.5 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG65470.1 - 3.7e-31 107.1 0.0 1.1e-30 105.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65470.1 - 5.3e-31 107.0 0.0 1.6e-30 105.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65470.1 - 6.8e-31 107.5 0.1 1.3e-30 106.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65470.1 - 5e-20 71.4 0.5 1.4e-19 69.9 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG65470.1 - 0.00046 20.4 0.1 0.0013 18.9 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG65470.1 - 0.29 10.7 0.0 0.29 10.7 0.0 2.8 2 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Retrotrans_gag PF03732.17 GBG65472.1 - 0.0065 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein PP-binding PF00550.25 GBG65474.1 - 2e-10 40.9 0.3 3e-10 40.3 0.3 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site S-layer PF07752.11 GBG65474.1 - 0.06 12.4 0.3 0.082 12.0 0.3 1.2 1 0 0 1 1 1 0 S-layer protein Integrase_H2C2 PF17921.1 GBG65475.1 - 1.1e-17 63.9 0.5 2.5e-17 62.7 0.3 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG65475.1 - 1.3e-15 57.6 0.0 4.1e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG65475.1 - 0.044 14.0 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger CNOT1_HEAT_N PF16419.5 GBG65475.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF1564 PF07600.11 GBG65475.1 - 0.15 11.7 0.0 0.37 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG65476.1 - 4.4e-11 42.7 0.0 6.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YrhC PF14143.6 GBG65476.1 - 0.07 13.2 0.9 0.18 11.9 0.5 1.8 2 0 0 2 2 2 0 YrhC-like protein SAP PF02037.27 GBG65476.1 - 0.58 10.0 2.4 2.5 7.9 0.4 2.2 2 0 0 2 2 2 0 SAP domain rve PF00665.26 GBG65479.1 - 4.1e-11 43.1 0.1 6.4e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain WD40 PF00400.32 GBG65480.1 - 3.5e-13 49.8 13.3 0.027 15.3 0.1 8.2 7 1 1 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG65480.1 - 3e-09 37.1 5.7 0.0055 17.0 0.1 5.4 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 GBG65480.1 - 0.013 14.6 0.3 0.12 11.4 0.2 2.4 2 0 0 2 2 2 0 Coatomer WD associated region Tachylectin PF14517.6 GBG65480.1 - 0.02 14.5 0.8 0.064 12.8 0.1 2.3 2 1 0 2 2 2 0 Tachylectin IKI3 PF04762.12 GBG65480.1 - 0.032 12.3 0.8 2.3 6.1 0.1 2.9 3 1 0 3 3 3 0 IKI3 family eIF2A PF08662.11 GBG65480.1 - 0.088 12.7 0.0 0.8 9.6 0.0 2.6 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A AP_endonuc_2 PF01261.24 GBG65480.1 - 0.13 11.6 0.4 0.46 9.9 0.2 1.9 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel TPR_19 PF14559.6 GBG65480.1 - 1.5 9.4 4.7 2.8 8.5 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG65481.1 - 1.4e-27 96.7 0.0 2.2e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65481.1 - 4.6e-20 71.5 0.0 1.2e-15 57.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65481.1 - 4.1e-11 43.1 0.0 1.1e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG65481.1 - 4.3e-11 42.5 0.0 8.3e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG65481.1 - 5.1e-11 42.5 0.9 1.5e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG65481.1 - 1.7e-08 34.7 0.0 3.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG65481.1 - 0.007 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG65481.1 - 0.085 13.5 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease GerE PF00196.19 GBG65482.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family TRAP_alpha PF03896.16 GBG65483.1 - 0.41 9.8 2.4 0.64 9.2 2.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDE_Tnp_4 PF13359.6 GBG65484.1 - 3.5e-25 88.5 0.0 7.2e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65484.1 - 5.3e-11 42.5 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG65484.1 - 0.088 12.4 0.2 3 7.4 0.1 2.2 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG65485.1 - 1.1e-10 41.7 4.0 1.8e-10 41.0 0.5 2.5 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG65485.1 - 0.011 16.1 0.4 0.025 14.9 0.4 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PASTA PF03793.19 GBG65485.1 - 0.06 13.2 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 PASTA domain RT_RNaseH_2 PF17919.1 GBG65487.1 - 3.4e-22 78.4 0.0 6.6e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65487.1 - 2.4e-21 76.0 0.0 4.5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65487.1 - 2.1e-10 40.5 0.0 4.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65487.1 - 1.4e-09 37.9 3.7 4.1e-09 36.4 3.7 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG65488.1 - 8.1e-22 77.1 0.0 1.6e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65488.1 - 5.3e-21 74.9 0.0 1.1e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG65488.1 - 0.0003 21.0 0.0 0.0014 18.9 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG65488.1 - 0.0017 17.9 0.1 0.0036 16.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RCS1 PF07326.11 GBG65488.1 - 0.26 11.2 5.9 0.48 10.3 5.9 1.3 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 Hamartin PF04388.12 GBG65488.1 - 0.51 9.0 1.8 0.73 8.4 1.8 1.1 1 0 0 1 1 1 0 Hamartin protein RVT_1 PF00078.27 GBG65489.1 - 9e-30 103.8 0.1 1.5e-29 103.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65489.1 - 2.9e-29 101.1 0.0 6.4e-29 99.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG65489.1 - 2.7e-26 92.2 0.0 2.7e-26 92.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG65489.1 - 1.9e-19 69.9 0.1 9.9e-19 67.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG65489.1 - 3.2e-06 26.8 0.1 8e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG65489.1 - 0.17 11.9 5.8 0.71 9.9 5.8 2.2 1 0 0 1 1 1 0 AT hook motif Retrotrans_gag PF03732.17 GBG65490.1 - 5.7e-05 23.3 1.5 8.7e-05 22.7 0.3 2.1 2 1 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG65491.1 - 1.4e-25 89.3 0.0 2.7e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65491.1 - 1.7e-21 76.5 0.0 3.2e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65491.1 - 9e-05 22.7 0.2 0.00032 20.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG65491.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF659 PF04937.15 GBG65492.1 - 2.2e-19 69.8 0.0 5.1e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65492.1 - 1.1e-05 25.2 0.1 2.4e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH PF17917.1 GBG65493.1 - 9.1e-20 70.9 0.1 2.8e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65493.1 - 7.1e-15 54.9 0.0 2.6e-14 53.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG65493.1 - 0.087 12.4 0.0 0.087 12.4 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Presenilin PF01080.17 GBG65493.1 - 0.89 8.2 3.7 1.2 7.8 3.7 1.2 1 0 0 1 1 1 0 Presenilin TetR_C_23 PF17931.1 GBG65493.1 - 4.9 7.3 7.4 13 6.0 0.1 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Presenilin PF01080.17 GBG65494.1 - 0.42 9.3 3.4 0.51 9.0 3.4 1.2 1 0 0 1 1 1 0 Presenilin TetR_C_23 PF17931.1 GBG65494.1 - 3.5 7.8 8.2 8 6.6 0.1 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PUD PF03714.14 GBG65495.1 - 0.1 13.5 0.0 0.2 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial pullanase-associated domain RVT_1 PF00078.27 GBG65496.1 - 1.2e-58 198.3 1.4 4.5e-29 101.6 0.2 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG65496.1 - 0.56 10.5 3.1 0.44 10.8 0.3 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Pico_P1A PF02226.16 GBG65497.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) RVT_1 PF00078.27 GBG65498.1 - 1.9e-34 119.1 0.4 7.6e-29 100.8 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG65498.1 - 2.1e-27 95.7 0.0 5.5e-27 94.4 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 GBG65498.1 - 2.7e-27 94.7 0.0 6.3e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65498.1 - 3.5e-18 65.8 0.1 1.7e-13 50.8 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65498.1 - 2e-16 59.8 0.5 6.2e-16 58.2 0.5 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Plant_tran PF04827.14 GBG65498.1 - 2.3e-13 50.2 0.0 4.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG65498.1 - 0.012 15.3 1.2 0.13 11.9 0.1 2.9 2 1 0 2 2 2 0 Transposase DDE domain DUF4140 PF13600.6 GBG65498.1 - 0.036 14.5 10.1 20 5.7 1.3 5.2 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Retrotrans_gag PF03732.17 GBG65498.1 - 0.046 14.0 0.8 5.2 7.4 0.0 4.0 3 0 0 3 3 3 0 Retrotransposon gag protein PH_5 PF15405.6 GBG65498.1 - 0.12 12.5 0.2 0.34 11.0 0.2 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Cep57_MT_bd PF06657.13 GBG65498.1 - 0.25 11.8 8.8 0.28 11.7 2.7 3.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SlyX PF04102.12 GBG65498.1 - 0.53 10.9 19.8 2.9 8.6 0.2 5.9 5 0 0 5 5 5 0 SlyX DUF4407 PF14362.6 GBG65498.1 - 7 5.9 8.0 9 5.6 4.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GBG65498.1 - 7.5 6.0 7.8 7.6 6.0 6.1 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit RT_RNaseH PF17917.1 GBG65499.1 - 1e-20 74.0 0.0 2.4e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65499.1 - 2.5e-15 56.3 0.3 5.4e-15 55.2 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65499.1 - 1e-14 54.6 0.2 6.4e-14 52.0 0.0 2.2 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65499.1 - 1.5e-13 50.6 0.0 4.3e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG65499.1 - 8.2e-08 32.1 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65499.1 - 7.1e-06 26.6 0.0 1.4e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65499.1 - 1e-05 26.0 0.0 1.9e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG65499.1 - 0.00068 19.5 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG65499.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG65500.1 - 1.2e-08 34.8 0.0 2.9e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65500.1 - 1.5e-06 28.8 0.0 2.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65500.1 - 1.9e-06 28.3 0.0 3.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG65500.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG65501.1 - 3.7e-35 121.4 0.0 6.4e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65501.1 - 5.4e-30 103.8 0.0 1.2e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65501.1 - 1.1e-28 99.2 0.0 2.8e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG65501.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65501.1 - 1.4e-05 25.7 0.0 2.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65501.1 - 7.7e-05 23.2 0.0 0.0002 21.8 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG65501.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG65501.1 - 0.022 14.6 0.0 0.057 13.2 0.0 1.7 1 1 1 2 2 2 0 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG65501.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG65503.1 - 2.9e-29 101.1 0.0 5.9e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65503.1 - 6.5e-25 87.5 0.0 1.4e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sec34 PF04136.15 GBG65503.1 - 0.037 13.9 0.2 0.097 12.5 0.1 1.8 2 0 0 2 2 2 0 Sec34-like family tRNA_lig_CPD PF08302.11 GBG65503.1 - 0.1 12.0 2.0 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain Phage_GPO PF05929.11 GBG65503.1 - 0.12 12.0 5.6 0.86 9.2 4.6 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Adaptin_binding PF10199.9 GBG65503.1 - 0.52 10.9 2.9 1.5 9.5 2.9 1.8 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Sugar_tr PF00083.24 GBG65505.1 - 2.5e-27 95.9 35.7 8.3e-25 87.5 10.7 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 GBG65505.1 - 9.3e-24 84.0 53.1 3.1e-16 59.2 30.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily gag-asp_proteas PF13975.6 GBG65506.1 - 6.2e-06 26.7 0.0 2.1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65506.1 - 0.0027 18.3 0.0 0.01 16.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG65506.1 - 0.0078 16.0 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG65506.1 - 0.075 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RNA_pol_Rpc4 PF05132.14 GBG65507.1 - 0.044 14.2 4.8 0.039 14.4 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 NOA36 PF06524.12 GBG65507.1 - 0.091 12.1 14.0 0.1 11.9 14.0 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GBG65507.1 - 0.12 12.0 12.0 0.17 11.6 12.0 1.3 1 0 0 1 1 1 0 FAM176 family RAB3GAP2_C PF14656.6 GBG65507.1 - 0.14 10.4 4.7 0.16 10.2 4.7 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF913 PF06025.12 GBG65507.1 - 0.35 9.8 6.2 0.33 9.9 6.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 GBG65507.1 - 0.38 10.9 8.2 0.38 10.9 8.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3438 PF11920.8 GBG65507.1 - 0.47 9.6 2.1 0.58 9.4 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Ureide_permease PF07168.11 GBG65507.1 - 0.59 8.8 1.9 0.53 9.0 1.9 1.0 1 0 0 1 1 1 0 Ureide permease DUF4746 PF15928.5 GBG65507.1 - 0.77 9.1 17.7 0.69 9.3 17.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FYDLN_acid PF09538.10 GBG65507.1 - 1.1 9.9 15.4 1.4 9.7 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 GBG65507.1 - 1.2 7.3 21.0 1.1 7.4 21.0 1.0 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 GBG65507.1 - 1.3 9.2 3.8 1.2 9.3 3.8 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 GBG65507.1 - 1.4 7.6 8.2 1.4 7.6 8.2 1.0 1 0 0 1 1 1 0 Presenilin TRAP_alpha PF03896.16 GBG65507.1 - 1.8 7.7 11.3 1.8 7.7 11.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4820 PF16091.5 GBG65507.1 - 2.6 7.4 10.0 2.6 7.4 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NARP1 PF12569.8 GBG65507.1 - 2.8 6.7 11.1 2.6 6.8 11.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_pol_3_Rpc31 PF11705.8 GBG65507.1 - 3.2 7.9 23.5 3.3 7.9 23.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PBP_sp32 PF07222.12 GBG65507.1 - 4.5 6.6 21.1 4.9 6.5 21.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Afi1 PF07792.12 GBG65507.1 - 5 7.6 11.6 5.6 7.5 11.6 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Serinc PF03348.15 GBG65507.1 - 6.3 5.6 5.4 6.4 5.6 5.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIF_alpha PF05793.12 GBG65507.1 - 6.3 5.3 24.9 6 5.3 24.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.14 GBG65507.1 - 7.9 6.2 21.7 8.8 6.1 21.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein UPF0184 PF03670.13 GBG65508.1 - 0.058 13.8 1.2 0.11 13.0 1.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) RVT_1 PF00078.27 GBG65510.1 - 3e-22 79.2 0.0 6.2e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65510.1 - 8.3e-19 67.5 0.0 4.5e-18 65.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65510.1 - 1.5e-11 44.5 0.0 4e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG65510.1 - 0.026 14.8 0.4 0.16 12.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2730 PF10805.8 GBG65510.1 - 0.13 12.4 0.1 0.39 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SlyX PF04102.12 GBG65510.1 - 2.7 8.7 5.8 5.8 7.6 0.0 4.0 5 0 0 5 5 5 0 SlyX RVT_1 PF00078.27 GBG65512.1 - 5.5e-30 104.5 0.0 1.3e-29 103.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65512.1 - 1.1e-13 51.1 0.0 2.2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65512.1 - 0.0087 16.3 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mito_carr PF00153.27 GBG65514.1 - 5.5e-51 170.5 1.5 5e-17 61.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LysM PF01476.20 GBG65517.1 - 3.7e-20 71.7 0.0 1e-08 35.1 0.0 2.3 2 0 0 2 2 2 2 LysM domain SR-25 PF10500.9 GBG65517.1 - 0.19 11.3 6.8 0.29 10.7 6.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RT_RNaseH PF17917.1 GBG65518.1 - 7.3e-43 145.1 0.0 7.8e-20 71.1 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65518.1 - 5.9e-42 141.8 0.0 1.8e-19 69.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65518.1 - 3.3e-37 126.4 11.3 2.2e-18 66.1 0.9 3.1 4 0 0 4 4 2 2 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG65518.1 - 5e-06 27.0 0.1 1.1e-05 25.9 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG65518.1 - 7.6e-05 22.8 3.2 0.34 11.2 0.2 3.0 2 0 0 2 2 2 2 H2C2 zinc finger rve PF00665.26 GBG65518.1 - 8.9e-05 22.7 0.0 0.15 12.3 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain PaRep2a PF07903.11 GBG65518.1 - 0.00043 20.1 0.2 1.8 8.5 0.0 2.8 2 0 0 2 2 2 2 PaRep2a protein Asp_protease_2 PF13650.6 GBG65518.1 - 0.00074 20.1 0.1 0.0016 19.0 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF4258 PF14076.6 GBG65518.1 - 0.001 19.4 0.0 3.7 8.0 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4258) RVT_1 PF00078.27 GBG65518.1 - 0.0028 17.2 0.0 17 4.8 0.0 3.3 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_LYR PF05347.15 GBG65518.1 - 0.019 15.0 0.2 13 5.9 0.0 3.0 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Asp_protease PF09668.10 GBG65518.1 - 0.019 14.7 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF3213 PF11491.8 GBG65518.1 - 0.04 14.1 0.3 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) HisKA_3 PF07730.13 GBG65518.1 - 0.088 13.3 0.1 50 4.5 0.0 3.4 3 0 0 3 3 3 0 Histidine kinase zf-CCHC PF00098.23 GBG65518.1 - 0.098 12.8 1.9 0.28 11.3 1.9 1.9 1 0 0 1 1 1 0 Zinc knuckle DMRL_synthase PF00885.19 GBG65518.1 - 0.12 12.2 0.0 23 4.8 0.0 2.3 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Antimicrobial12 PF08107.11 GBG65518.1 - 0.21 11.4 0.0 37 4.2 0.0 2.6 3 0 0 3 3 2 0 Pleurocidin family RT_RNaseH PF17917.1 GBG65519.1 - 4.1e-43 145.9 0.0 6.1e-20 71.5 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65519.1 - 3.3e-42 142.6 0.0 1.4e-19 70.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65519.1 - 1.3e-37 127.6 10.8 1.7e-18 66.4 0.9 3.2 4 0 0 4 4 2 2 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG65519.1 - 4.2e-06 27.2 0.1 8.6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG65519.1 - 4.5e-05 23.6 3.2 0.27 11.5 0.2 3.0 2 0 0 2 2 2 2 H2C2 zinc finger rve PF00665.26 GBG65519.1 - 5.7e-05 23.3 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain PaRep2a PF07903.11 GBG65519.1 - 0.00027 20.8 0.2 1.4 8.8 0.0 2.8 2 0 0 2 2 2 2 PaRep2a protein DUF4258 PF14076.6 GBG65519.1 - 0.00061 20.1 0.0 2.9 8.3 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4258) Asp_protease_2 PF13650.6 GBG65519.1 - 0.00065 20.3 0.1 0.0013 19.4 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG65519.1 - 0.0014 18.2 0.0 13 5.2 0.0 3.3 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_LYR PF05347.15 GBG65519.1 - 0.011 15.8 0.2 10 6.2 0.0 3.1 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Asp_protease PF09668.10 GBG65519.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF3213 PF11491.8 GBG65519.1 - 0.025 14.8 0.3 14 6.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) DMRL_synthase PF00885.19 GBG65519.1 - 0.074 12.9 0.0 19 5.1 0.0 2.4 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase HisKA_3 PF07730.13 GBG65519.1 - 0.11 13.1 0.0 40 4.8 0.0 3.0 2 0 0 2 2 2 0 Histidine kinase Antimicrobial12 PF08107.11 GBG65519.1 - 0.12 12.1 0.0 30 4.5 0.0 2.7 3 0 0 3 3 3 0 Pleurocidin family Fer4_8 PF13183.6 GBG65519.1 - 0.24 11.9 1.6 50 4.5 0.1 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain Presenilin PF01080.17 GBG65522.1 - 1.1 8.0 32.9 1.2 7.9 32.9 1.0 1 0 0 1 1 1 0 Presenilin DUF2126 PF09899.9 GBG65523.1 - 0.018 13.2 5.8 0.02 13.0 5.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PTPRCAP PF15713.5 GBG65523.1 - 0.028 14.7 29.3 0.035 14.4 29.3 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GBG65523.1 - 0.34 9.1 29.3 0.39 8.9 29.3 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG65523.1 - 0.57 8.6 31.3 0.67 8.3 31.3 1.0 1 0 0 1 1 1 0 Mpp10 protein API5 PF05918.11 GBG65523.1 - 1.2 7.9 10.7 1.4 7.6 10.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Gti1_Pac2 PF09729.9 GBG65523.1 - 1.3 9.1 7.8 1.6 8.8 7.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF3306 PF11748.8 GBG65523.1 - 1.3 9.9 20.0 2 9.3 20.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Paf1 PF03985.13 GBG65523.1 - 1.6 7.6 34.4 2.1 7.2 34.4 1.1 1 0 0 1 1 1 0 Paf1 DUF3807 PF12720.7 GBG65523.1 - 2 8.6 22.4 2.6 8.3 22.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) XRN_M PF17846.1 GBG65523.1 - 3.1 6.6 13.7 3.7 6.4 13.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain RNA_polI_A34 PF08208.11 GBG65523.1 - 3.3 7.8 27.8 3.8 7.5 27.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 GBG65523.1 - 3.4 6.3 17.1 3.8 6.2 17.1 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG65523.1 - 4.3 5.5 28.1 5 5.3 28.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG65523.1 - 4.3 7.1 24.7 5.1 6.8 24.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 GBG65523.1 - 4.6 7.2 5.8 5.3 7.0 5.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MPM1 PF17234.2 GBG65523.1 - 5.1 7.3 15.3 7.4 6.8 15.3 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 BUD22 PF09073.10 GBG65523.1 - 5.3 6.3 27.3 6.3 6.0 27.3 1.1 1 0 0 1 1 1 0 BUD22 SLC12 PF03522.15 GBG65523.1 - 5.3 6.0 9.7 6 5.8 9.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CLN3 PF02487.17 GBG65523.1 - 5.9 5.8 5.2 6.4 5.7 5.2 1.1 1 0 0 1 1 1 0 CLN3 protein DDHD PF02862.17 GBG65523.1 - 7.6 6.6 6.9 11 6.1 6.9 1.3 1 0 0 1 1 1 0 DDHD domain MDM1 PF15501.6 GBG65523.1 - 8.1 5.5 24.2 9.9 5.2 24.2 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 SelP_N PF04592.14 GBG65523.1 - 8.6 5.7 14.4 11 5.4 14.4 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FGF-BP1 PF06473.12 GBG65523.1 - 8.9 6.1 14.3 11 5.8 14.3 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF2151 PF10221.9 GBG65523.1 - 9.2 4.7 11.2 9.9 4.6 11.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Spore_coat_CotO PF14153.6 GBG65523.1 - 9.8 6.1 24.0 12 5.8 24.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Myb_DNA-bind_4 PF13837.6 GBG65524.1 - 5.8e-06 26.6 1.6 1e-05 25.8 1.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG65524.1 - 0.0017 18.4 1.3 0.0028 17.7 1.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF2615 PF11027.8 GBG65524.1 - 0.0029 17.7 0.4 0.007 16.5 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) FAM176 PF14851.6 GBG65524.1 - 0.11 12.1 5.2 0.34 10.6 5.2 1.8 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 GBG65524.1 - 0.12 11.5 33.9 0.26 10.4 33.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1676 PF07898.13 GBG65524.1 - 0.33 11.0 9.5 0.75 9.8 9.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Sigma70_ner PF04546.13 GBG65524.1 - 1.5 8.7 13.3 3.1 7.6 13.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.16 GBG65524.1 - 5.5 6.1 16.1 9 5.4 16.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 GBG65524.1 - 7.1 6.0 21.0 14 5.0 21.0 1.4 1 0 0 1 1 1 0 SDA1 DDE_Tnp_4 PF13359.6 GBG65525.1 - 2.9e-23 82.3 0.0 4.7e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65525.1 - 1.7e-15 57.2 0.0 2.4e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DUF4651 PF15513.6 GBG65525.1 - 0.0039 17.0 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4651) DDE_Tnp_1 PF01609.21 GBG65525.1 - 0.024 14.3 5.2 0.038 13.6 1.8 2.7 2 1 0 2 2 2 0 Transposase DDE domain DUF2615 PF11027.8 GBG65526.1 - 0.00045 20.3 0.2 0.00076 19.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) DUF2457 PF10446.9 GBG65526.1 - 0.019 14.2 33.3 0.023 13.8 33.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 GBG65526.1 - 0.026 13.9 15.2 0.03 13.8 15.2 1.1 1 0 0 1 1 1 0 SDA1 DUF3486 PF11985.8 GBG65526.1 - 0.13 12.7 1.4 0.2 12.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Sigma70_ner PF04546.13 GBG65526.1 - 0.3 10.9 13.7 0.48 10.3 13.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.16 GBG65526.1 - 0.85 8.8 16.1 1.2 8.3 16.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_3_Rpc31 PF11705.8 GBG65526.1 - 1.9 8.7 36.5 2.4 8.3 36.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.12 GBG65526.1 - 5.8 6.2 21.2 8.3 5.7 21.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFB6 PF17110.5 GBG65526.1 - 6 6.6 12.7 12 5.6 12.7 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop14 PF04147.12 GBG65526.1 - 9.5 4.3 25.8 11 4.0 25.8 1.0 1 0 0 1 1 1 0 Nop14-like family GcpE PF04551.14 GBG65527.1 - 6.6e-37 127.4 1.1 2.4e-20 72.9 0.0 2.9 2 1 1 3 3 3 2 GcpE protein SDA1 PF05285.12 GBG65527.1 - 3.7e-05 23.3 9.7 4.6e-05 23.0 9.7 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GBG65527.1 - 0.00058 19.3 7.1 0.00074 19.0 7.1 1.2 1 0 0 1 1 1 1 BUD22 Mpp10 PF04006.12 GBG65527.1 - 0.0039 15.7 15.5 0.0057 15.2 15.5 1.2 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 GBG65527.1 - 0.0064 14.8 16.5 0.0087 14.3 16.5 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 GBG65527.1 - 0.0068 14.8 10.8 0.0089 14.4 10.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 GBG65527.1 - 0.028 13.2 8.8 0.04 12.7 8.8 1.2 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 GBG65527.1 - 0.028 13.7 11.4 0.046 13.1 11.4 1.3 1 0 0 1 1 1 0 NOA36 protein SpoIIP PF07454.11 GBG65527.1 - 0.038 13.4 6.9 0.085 12.3 6.9 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 GBG65527.1 - 0.052 13.7 0.3 0.07 13.3 0.3 1.2 1 0 0 1 1 1 0 DDHD domain DUF3391 PF11871.8 GBG65527.1 - 0.078 13.5 4.7 0.37 11.3 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) RR_TM4-6 PF06459.12 GBG65527.1 - 0.11 12.4 12.3 0.18 11.6 12.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 GBG65527.1 - 0.14 12.2 12.3 0.23 11.5 12.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CPSF100_C PF13299.6 GBG65527.1 - 0.31 11.2 8.7 0.56 10.4 8.7 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 GBG65527.1 - 0.39 9.9 1.1 0.52 9.5 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 GBG65527.1 - 0.5 9.1 3.3 0.68 8.6 3.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.13 GBG65527.1 - 0.73 8.8 25.9 1.3 7.9 25.9 1.3 1 0 0 1 1 1 0 Paf1 DUF3408 PF11888.8 GBG65527.1 - 1.5 9.0 13.9 2.8 8.1 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RNA_pol_Rpc4 PF05132.14 GBG65527.1 - 1.6 9.1 9.1 3.5 8.1 9.1 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Myc_N PF01056.18 GBG65527.1 - 2.4 8.0 8.0 5.8 6.7 8.0 1.6 1 0 0 1 1 1 0 Myc amino-terminal region TFIIF_alpha PF05793.12 GBG65527.1 - 3.3 6.2 23.5 4.8 5.6 23.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC27 PF09507.10 GBG65527.1 - 3.4 6.9 15.0 6 6.1 15.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Connexin PF00029.19 GBG65527.1 - 3.9 7.2 9.5 6.3 6.5 9.5 1.2 1 0 0 1 1 1 0 Connexin CobT PF06213.12 GBG65527.1 - 5.1 6.4 27.2 9.4 5.5 27.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 GBG65527.1 - 6.3 5.5 9.4 45 2.6 10.7 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 GBG65527.1 - 7.1 4.6 28.3 10 4.1 28.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi G0-G1_switch_2 PF15103.6 GBG65527.1 - 9.5 6.7 7.6 25 5.4 7.6 1.7 1 0 0 1 1 1 0 G0/G1 switch protein 2 V_ATPase_I PF01496.19 GBG65527.1 - 9.6 4.0 9.7 13 3.5 9.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAM33 PF02330.16 GBG65528.1 - 6.3e-31 108.0 0.0 8.6e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Rhomboid PF01694.22 GBG65529.1 - 1.8e-36 125.4 10.3 4e-36 124.3 10.3 1.6 1 0 0 1 1 1 1 Rhomboid family DUF659 PF04937.15 GBG65531.1 - 5.6e-08 32.8 0.0 9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myosin_head PF00063.21 GBG65533.1 - 5.2e-190 633.0 3.1 3.3e-90 303.2 0.1 3.5 3 1 1 4 4 3 3 Myosin head (motor domain) RVT_1 PF00078.27 GBG65533.1 - 5e-27 94.9 0.3 2.4e-26 92.7 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65533.1 - 2.3e-22 79.3 0.2 2.9e-21 75.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65533.1 - 9.7e-20 70.5 0.0 2.9e-19 68.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65533.1 - 2e-09 37.7 0.0 7e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Myosin_N PF02736.19 GBG65533.1 - 4.4e-08 32.8 1.0 1e-07 31.6 1.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 GBG65533.1 - 8.3e-08 31.4 24.5 0.21 11.4 0.2 6.4 6 0 0 6 6 6 4 IQ calmodulin-binding motif Integrase_H2C2 PF17921.1 GBG65533.1 - 1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG65533.1 - 0.0003 21.4 0.0 0.0011 19.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65533.1 - 0.0025 18.4 0.0 0.0095 16.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Nuc_N PF14448.6 GBG65533.1 - 0.028 14.3 6.5 6.8 6.6 0.0 4.8 4 1 1 5 5 5 0 Nuclease N terminal AAA_16 PF13191.6 GBG65533.1 - 0.042 14.2 0.0 0.042 14.2 0.0 4.5 4 1 0 4 4 1 0 AAA ATPase domain DUF3800 PF12686.7 GBG65533.1 - 0.095 13.3 0.1 1.7 9.3 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) Myosin_head PF00063.21 GBG65534.1 - 5.2e-190 633.0 3.1 3.3e-90 303.2 0.1 3.5 3 1 1 4 4 3 3 Myosin head (motor domain) RVT_1 PF00078.27 GBG65534.1 - 5e-27 94.9 0.3 2.4e-26 92.7 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65534.1 - 2.3e-22 79.3 0.2 2.9e-21 75.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65534.1 - 9.7e-20 70.5 0.0 2.9e-19 69.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65534.1 - 2e-09 37.7 0.0 7e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Myosin_N PF02736.19 GBG65534.1 - 4.4e-08 32.8 1.0 1e-07 31.6 1.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 GBG65534.1 - 8.3e-08 31.4 24.5 0.21 11.4 0.2 6.4 6 0 0 6 6 6 4 IQ calmodulin-binding motif Integrase_H2C2 PF17921.1 GBG65534.1 - 1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG65534.1 - 0.0003 21.4 0.0 0.0011 19.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65534.1 - 0.0024 18.4 0.0 0.0095 16.5 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Nuc_N PF14448.6 GBG65534.1 - 0.0079 16.0 3.9 6.8 6.6 0.0 4.4 3 1 1 4 4 4 1 Nuclease N terminal AAA_16 PF13191.6 GBG65534.1 - 0.042 14.2 0.0 0.042 14.2 0.0 4.5 4 1 0 4 4 1 0 AAA ATPase domain DUF3800 PF12686.7 GBG65534.1 - 0.095 13.3 0.1 1.7 9.3 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) Myosin_head PF00063.21 GBG65535.1 - 5.2e-190 633.0 3.1 3.3e-90 303.2 0.1 3.5 3 1 1 4 4 3 3 Myosin head (motor domain) RVT_1 PF00078.27 GBG65535.1 - 5e-27 94.9 0.3 2.4e-26 92.7 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65535.1 - 2.3e-22 79.2 0.2 2.9e-21 75.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65535.1 - 9.7e-20 70.5 0.0 2.9e-19 69.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65535.1 - 2e-09 37.7 0.0 7e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Myosin_N PF02736.19 GBG65535.1 - 4.4e-08 32.8 1.0 1e-07 31.6 1.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 GBG65535.1 - 8.3e-08 31.4 24.5 0.21 11.4 0.2 6.4 6 0 0 6 6 6 4 IQ calmodulin-binding motif Integrase_H2C2 PF17921.1 GBG65535.1 - 1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG65535.1 - 0.0003 21.4 0.0 0.0011 19.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65535.1 - 0.0024 18.4 0.0 0.0095 16.5 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Nuc_N PF14448.6 GBG65535.1 - 0.0079 16.0 3.9 6.8 6.6 0.0 4.4 3 1 1 4 4 4 1 Nuclease N terminal AAA_16 PF13191.6 GBG65535.1 - 0.042 14.2 0.0 0.042 14.2 0.0 4.5 4 1 0 4 4 1 0 AAA ATPase domain DUF3800 PF12686.7 GBG65535.1 - 0.096 13.3 0.1 1.7 9.3 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) Myosin_head PF00063.21 GBG65536.1 - 5e-190 633.1 3.1 3.3e-90 303.2 0.1 3.5 3 1 1 4 4 3 3 Myosin head (motor domain) RVT_1 PF00078.27 GBG65536.1 - 4.9e-27 94.9 0.3 2.3e-26 92.7 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65536.1 - 2.3e-22 79.3 0.2 2.9e-21 75.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65536.1 - 1e-19 70.4 0.0 2.9e-19 69.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65536.1 - 2e-09 37.7 0.0 6.9e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Myosin_N PF02736.19 GBG65536.1 - 4.3e-08 32.9 1.0 1e-07 31.7 1.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 GBG65536.1 - 7.6e-08 31.5 24.5 0.21 11.5 0.2 6.4 6 0 0 6 6 6 4 IQ calmodulin-binding motif Integrase_H2C2 PF17921.1 GBG65536.1 - 1e-06 28.8 0.0 2.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG65536.1 - 0.0003 21.4 0.0 0.0011 19.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65536.1 - 0.0024 18.4 0.0 0.0094 16.5 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Nuc_N PF14448.6 GBG65536.1 - 0.0077 16.1 3.9 6.7 6.6 0.0 4.4 3 1 1 4 4 4 1 Nuclease N terminal AAA_16 PF13191.6 GBG65536.1 - 0.041 14.3 0.0 0.041 14.3 0.0 4.5 4 1 0 4 4 2 0 AAA ATPase domain DUF3800 PF12686.7 GBG65536.1 - 0.095 13.3 0.2 1.6 9.4 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) PseudoU_synth_1 PF01416.20 GBG65537.1 - 9.7e-09 35.7 0.0 2e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF659 PF04937.15 GBG65538.1 - 5.8e-14 52.2 0.1 1.1e-13 51.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) YdiH PF15930.5 GBG65538.1 - 0.19 11.9 0.1 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function Myb_DNA-bind_4 PF13837.6 GBG65540.1 - 1.9e-06 28.2 0.7 3.3e-06 27.4 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG65540.1 - 0.088 13.0 0.1 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2390 PF09523.10 GBG65540.1 - 0.11 12.9 0.2 0.28 11.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Myb_DNA-bind_4 PF13837.6 GBG65541.1 - 4.9e-08 33.2 0.6 1.9e-07 31.4 0.2 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG65541.1 - 0.003 17.6 0.5 0.0092 16.0 0.5 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG65542.1 - 6.3e-30 103.9 0.0 1e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65542.1 - 1.4e-13 50.9 0.0 2.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG65542.1 - 2.9e-06 27.1 3.0 0.0036 17.0 0.0 3.5 3 1 0 3 3 3 2 Transposase DDE domain DUF659 PF04937.15 GBG65544.1 - 1.3e-10 41.4 0.0 2.6e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Borrelia_P83 PF05262.11 GBG65544.1 - 4.8 5.6 21.5 8.8 4.7 21.5 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Tai4 PF16695.5 GBG65545.1 - 0.12 13.0 1.2 0.59 10.7 1.2 2.3 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein Spo0A_C PF08769.11 GBG65545.1 - 0.69 10.0 3.4 12 6.0 0.8 2.7 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal Diphthamide_syn PF01866.17 GBG65545.1 - 1.4 8.3 4.8 0.16 11.4 0.4 1.7 2 0 0 2 2 2 0 Putative diphthamide synthesis protein PLAC8 PF04749.17 GBG65546.1 - 2.6e-21 76.5 20.4 3.2e-21 76.2 20.4 1.1 1 0 0 1 1 1 1 PLAC8 family DUF3270 PF11674.8 GBG65546.1 - 0.038 14.2 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Phage_holin_3_6 PF07332.11 GBG65546.1 - 0.05 13.7 4.9 0.067 13.2 4.9 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III CK_II_beta PF01214.18 GBG65546.1 - 0.64 9.8 5.6 0.9 9.3 5.6 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit DUF4131 PF13567.6 GBG65546.1 - 2.7 7.6 6.9 3.9 7.1 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Presenilin PF01080.17 GBG65547.1 - 0.00033 19.5 1.0 0.00033 19.5 1.0 1.0 1 0 0 1 1 1 1 Presenilin eIF3_subunit PF08597.10 GBG65547.1 - 0.011 15.7 29.8 0.013 15.4 29.8 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4366 PF14283.6 GBG65547.1 - 0.26 11.3 4.3 1 9.4 4.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Zip PF02535.22 GBG65547.1 - 0.43 9.8 2.2 0.52 9.5 2.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.12 GBG65547.1 - 0.67 9.3 24.9 0.85 9.0 24.9 1.0 1 0 0 1 1 1 0 SDA1 DUF2151 PF10221.9 GBG65547.1 - 3.9 6.0 6.5 4.6 5.7 6.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator rve PF00665.26 GBG65548.1 - 6.8e-14 52.1 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG65548.1 - 0.02 15.0 0.3 0.039 14.1 0.3 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain Chromo PF00385.24 GBG65548.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG65548.1 - 0.11 12.2 0.0 4.9 6.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1564) Nop14 PF04147.12 GBG65549.1 - 0.075 11.2 6.9 0.15 10.3 6.9 1.4 1 0 0 1 1 1 0 Nop14-like family REV1_C PF16727.5 GBG65549.1 - 0.28 11.6 4.3 0.22 12.0 2.1 2.0 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Chorion_2 PF03964.15 GBG65549.1 - 2.3 9.1 8.3 0.67 10.8 2.1 2.6 2 0 0 2 2 2 0 Chorion family 2 DUF2967 PF11179.8 GBG65550.1 - 0.046 11.8 4.7 0.047 11.8 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF659 PF04937.15 GBG65552.1 - 3.5e-06 27.0 0.0 6.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GCHY-1 PF02649.14 GBG65552.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 DUF659 PF04937.15 GBG65553.1 - 7.6e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65553.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region CDC45 PF02724.14 GBG65553.1 - 0.22 9.8 7.7 0.32 9.2 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PLAC8 PF04749.17 GBG65554.1 - 1.7e-17 64.2 17.2 3.6e-17 63.2 17.2 1.5 1 1 0 1 1 1 1 PLAC8 family DUF3810 PF12725.7 GBG65554.1 - 0.082 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) SDA1 PF05285.12 GBG65556.1 - 0.56 9.6 19.4 0.66 9.4 19.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG65556.1 - 1 7.6 15.5 1.4 7.2 15.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 GBG65556.1 - 2.1 8.0 8.7 2.9 7.5 8.7 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PPP4R2 PF09184.11 GBG65556.1 - 4.8 6.7 16.6 6.7 6.2 16.6 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GBG65556.1 - 5.6 5.1 23.0 7.1 4.7 23.0 1.0 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.23 GBG65558.1 - 9.5e-05 22.3 3.1 0.00023 21.1 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle PSGP PF07276.11 GBG65558.1 - 0.34 11.4 2.5 1.2 9.6 2.5 2.0 1 0 0 1 1 1 0 Apopolysialoglycoprotein (PSGP) zf-CCHC_4 PF14392.6 GBG65558.1 - 1.8 8.4 5.2 0.71 9.7 2.4 1.8 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG65559.1 - 1.1e-32 112.0 0.0 3.7e-16 59.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65559.1 - 4.3e-31 107.3 0.0 9e-31 106.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65559.1 - 1.2e-27 96.9 0.2 2.2e-27 96.0 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLAC8 PF04749.17 GBG65561.1 - 2.4e-13 50.9 0.6 2.8e-13 50.7 0.6 1.2 1 0 0 1 1 1 1 PLAC8 family TMEM135_C_rich PF15982.5 GBG65561.1 - 0.011 16.3 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 DUF3810 PF12725.7 GBG65561.1 - 0.12 11.7 0.1 0.13 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) PLAC8 PF04749.17 GBG65562.1 - 1.1e-09 39.2 0.0 1.8e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 PLAC8 family Cys_rich_FGFR PF00839.17 GBG65563.1 - 1.6e-37 127.4 45.0 7.1e-13 48.5 0.5 7.9 8 0 0 8 8 8 7 Cysteine rich repeat RT_RNaseH PF17917.1 GBG65564.1 - 3.3e-23 82.0 0.0 8.4e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65564.1 - 1.8e-20 72.8 0.0 3.8e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65564.1 - 2.4e-07 30.5 0.0 5.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Jnk-SapK_ap_N PF09744.9 GBG65564.1 - 0.19 11.9 10.7 0.019 15.2 5.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 YqzH PF14164.6 GBG65564.1 - 0.2 11.7 0.2 0.5 10.5 0.2 1.6 1 0 0 1 1 1 0 YqzH-like protein Csm1_N PF18504.1 GBG65564.1 - 0.86 10.0 5.7 2.9 8.3 2.5 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain RT_RNaseH PF17917.1 GBG65565.1 - 1.6e-23 83.0 0.0 3.7e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65565.1 - 9.1e-21 73.8 0.0 1.8e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65565.1 - 1.1e-07 31.6 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APP_E2 PF12925.7 GBG65566.1 - 0.0065 16.2 1.3 0.0082 15.9 0.4 1.4 1 1 1 2 2 2 1 E2 domain of amyloid precursor protein POTRA_2 PF08479.11 GBG65566.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type Thioredoxin PF00085.20 GBG65567.1 - 1.8e-20 72.8 0.0 2.9e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG65567.1 - 4.8e-08 33.4 0.0 1.4e-07 32.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GBG65567.1 - 3.6e-05 23.3 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GBG65567.1 - 7.6e-05 22.8 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 GBG65567.1 - 0.0032 17.3 0.0 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 GBG65567.1 - 0.0065 16.8 0.0 1.9 8.9 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Eapp_C PF10238.9 GBG65567.1 - 0.035 14.2 0.4 0.067 13.3 0.4 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein Redoxin PF08534.10 GBG65567.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Redoxin Presenilin PF01080.17 GBG65567.1 - 0.33 9.7 0.1 0.35 9.6 0.1 1.1 1 0 0 1 1 1 0 Presenilin RPA43_OB PF17875.1 GBG65567.1 - 2.1 9.0 5.0 4.3 8.0 5.0 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Tim54 PF11711.8 GBG65567.1 - 3.6 6.3 11.5 5.3 5.7 11.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ORC_WH_C PF18137.1 GBG65567.1 - 4.6 7.3 9.5 8.7 6.4 9.5 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Connexin PF00029.19 GBG65567.1 - 8.1 6.1 9.3 12 5.6 9.3 1.2 1 0 0 1 1 1 0 Connexin Thioredoxin PF00085.20 GBG65568.1 - 6.5e-21 74.2 0.0 1.1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG65568.1 - 1.4e-08 35.1 0.0 5.3e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GBG65568.1 - 1.3e-05 24.7 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GBG65568.1 - 3.6e-05 23.9 0.0 7.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 GBG65568.1 - 0.001 18.9 11.7 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 GBG65568.1 - 0.0017 18.7 0.0 0.57 10.5 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like PTPRCAP PF15713.5 GBG65568.1 - 0.008 16.5 2.3 0.014 15.7 2.3 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Eapp_C PF10238.9 GBG65568.1 - 0.018 15.1 0.4 0.028 14.5 0.4 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Redoxin PF08534.10 GBG65568.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Redoxin Thioredoxin_5 PF13743.6 GBG65568.1 - 0.036 13.7 0.0 0.14 11.8 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin Presenilin PF01080.17 GBG65568.1 - 0.34 9.6 1.1 0.41 9.4 1.1 1.1 1 0 0 1 1 1 0 Presenilin RPA43_OB PF17875.1 GBG65568.1 - 0.84 10.3 4.7 1.5 9.4 4.7 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Tim54 PF11711.8 GBG65568.1 - 1.7 7.4 11.5 2.4 6.8 11.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ORC_WH_C PF18137.1 GBG65568.1 - 2.3 8.3 9.5 4 7.5 9.5 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Connexin PF00029.19 GBG65568.1 - 4 7.1 9.3 5.3 6.7 9.3 1.2 1 0 0 1 1 1 0 Connexin Afi1 PF07792.12 GBG65568.1 - 8.1 6.9 7.5 14 6.1 7.5 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FAM176 PF14851.6 GBG65568.1 - 9.2 5.9 10.6 6.3 6.5 8.6 1.7 2 0 0 2 2 2 0 FAM176 family DUF4770 PF15994.5 GBG65568.1 - 9.6 6.4 8.9 16 5.7 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SR-25 PF10500.9 GBG65568.1 - 9.8 5.7 22.0 17 4.9 22.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TAL_FSA PF00923.19 GBG65569.1 - 3.1e-84 282.7 0.0 3.8e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Asp1 PF16993.5 GBG65569.1 - 0.03 13.6 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system protein Asp1 RVT_1 PF00078.27 GBG65570.1 - 1e-29 103.7 0.1 1.6e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65570.1 - 1.6e-29 102.3 0.0 4.7e-29 100.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65570.1 - 5.7e-29 100.1 0.0 1.1e-13 51.0 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase PEPcase PF00311.17 GBG65571.1 - 9e-292 969.9 0.3 6.7e-233 775.2 0.0 2.0 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 GBG65571.1 - 4.7e-05 22.1 0.0 0.00012 20.8 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxylase RVT_1 PF00078.27 GBG65572.1 - 3.9e-21 75.6 0.0 1.1e-20 74.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG65572.1 - 2.1e-07 31.5 0.0 1.1e-06 29.2 0.0 2.3 3 0 0 3 3 3 1 Aspartyl protease RVP_2 PF08284.11 GBG65572.1 - 4.8e-07 29.6 0.0 1.9e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG65572.1 - 1.5e-05 25.4 0.0 0.0001 22.8 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1664 PF07889.12 GBG65572.1 - 0.0043 17.1 3.4 0.0046 17.0 1.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) RVP PF00077.20 GBG65572.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG65572.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease TolA_bind_tri PF16331.5 GBG65572.1 - 0.11 12.6 8.3 0.33 11.0 8.3 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation CorA PF01544.18 GBG65572.1 - 0.72 9.1 3.2 0.47 9.7 0.5 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein RVT_1 PF00078.27 GBG65574.1 - 4.4e-31 108.1 0.1 6.3e-31 107.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65574.1 - 4.2e-24 84.5 0.0 8.9e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65574.1 - 1.3e-15 57.5 0.0 2.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG65574.1 - 1.7e-08 35.0 0.0 3.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65574.1 - 2.4e-08 33.8 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG65574.1 - 2.6e-06 27.9 0.0 5.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG65574.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG65574.1 - 0.038 13.1 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 MPP6 PF10175.9 GBG65575.1 - 1.2 9.6 9.3 0.18 12.3 3.3 2.4 2 0 0 2 2 2 0 M-phase phosphoprotein 6 DDE_Tnp_4 PF13359.6 GBG65576.1 - 1.6e-15 57.2 0.0 1.4e-14 54.0 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease SAP PF02037.27 GBG65576.1 - 7.8e-05 22.3 0.1 0.00022 20.9 0.1 1.8 1 0 0 1 1 1 1 SAP domain Plant_tran PF04827.14 GBG65576.1 - 0.0013 18.4 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG65576.1 - 0.042 14.2 0.3 0.51 10.8 0.0 2.6 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG65576.1 - 0.068 12.8 0.2 2.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain JCAD PF15351.6 GBG65576.1 - 0.26 9.0 6.3 0.34 8.6 6.3 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease FlaC_arch PF05377.11 GBG65577.1 - 0.25 11.7 8.8 5.8 7.4 0.1 4.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF2407_C PF13373.6 GBG65577.1 - 10 6.3 6.9 15 5.7 0.0 3.2 3 1 1 4 4 4 0 DUF2407 C-terminal domain rve PF00665.26 GBG65578.1 - 1.6e-10 41.2 0.0 3.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG65578.1 - 0.013 15.5 1.5 0.039 13.9 1.5 1.8 1 0 0 1 1 1 0 Zinc knuckle Collagen PF01391.18 GBG65578.1 - 3.7 7.4 6.6 0.24 11.2 1.0 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Rrn6 PF10214.9 GBG65578.1 - 4 5.8 15.0 2.3 6.6 1.2 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor zf-CCHC PF00098.23 GBG65579.1 - 0.00035 20.5 5.8 0.00035 20.5 5.8 1.8 2 0 0 2 2 2 1 Zinc knuckle DUF3464 PF11947.8 GBG65579.1 - 0.01 15.6 2.0 0.016 15.0 2.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2680 PF10925.8 GBG65579.1 - 0.044 13.8 0.0 0.044 13.8 0.0 3.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2680) DUF4763 PF15960.5 GBG65579.1 - 0.15 11.4 13.3 0.52 9.6 10.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF4407 PF14362.6 GBG65579.1 - 0.21 10.9 11.9 0.28 10.5 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 GBG65579.1 - 3.2 6.8 11.8 4.3 6.3 11.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_11 PF13086.6 GBG65579.1 - 3.8 7.2 9.6 1 9.1 6.4 1.6 1 1 1 2 2 2 0 AAA domain Sec62 PF03839.16 GBG65579.1 - 4 6.9 6.9 5 6.6 6.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Nop14 PF04147.12 GBG65580.1 - 0.0017 16.7 5.4 0.0017 16.7 5.4 1.1 1 0 0 1 1 1 1 Nop14-like family DDHD PF02862.17 GBG65580.1 - 0.17 12.0 0.7 0.21 11.7 0.7 1.1 1 0 0 1 1 1 0 DDHD domain BUD22 PF09073.10 GBG65580.1 - 0.17 11.2 13.6 0.21 10.9 13.6 1.0 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 GBG65580.1 - 0.2 11.9 17.9 0.25 11.6 17.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BRF1 PF07741.13 GBG65580.1 - 0.52 10.7 10.5 0.32 11.4 8.6 1.5 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Trypan_PARP PF05887.11 GBG65580.1 - 0.75 9.8 10.1 0.98 9.4 10.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 GBG65580.1 - 2.3 6.4 12.5 2.7 6.2 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 GBG65580.1 - 4.7 7.5 9.8 6.1 7.1 9.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.14 GBG65580.1 - 6.5 6.5 10.1 10 5.9 10.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4637 PF15470.6 GBG65580.1 - 8 6.2 13.6 11 5.8 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) COPI_C PF06957.11 GBG65580.1 - 8.1 5.1 12.4 9.6 4.8 12.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Paf1 PF03985.13 GBG65580.1 - 9.5 5.1 16.1 11 4.8 16.1 1.1 1 0 0 1 1 1 0 Paf1 EzrA PF06160.12 GBG65581.1 - 0.095 10.9 0.0 0.095 10.9 0.0 2.0 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA PspB PF06667.12 GBG65581.1 - 1.4 9.0 3.1 6 7.0 0.0 2.9 3 0 0 3 3 3 0 Phage shock protein B DUF484 PF04340.12 GBG65581.1 - 1.8 8.2 10.1 0.62 9.7 6.2 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF484 RVT_1 PF00078.27 GBG65582.1 - 1.3e-28 100.0 0.1 1.9e-28 99.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG65582.1 - 5e-08 33.4 0.0 1.1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65582.1 - 1.6e-07 31.9 0.0 4.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65582.1 - 4.9e-07 29.6 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG65582.1 - 1.8e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG65582.1 - 0.00061 19.8 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65583.1 - 7.2e-49 163.9 0.0 2.6e-24 85.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65583.1 - 5.1e-44 148.8 0.0 5.5e-21 74.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65583.1 - 2.5e-14 53.1 0.2 5.5e-14 52.0 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65583.1 - 3.8e-09 36.8 0.2 1.4e-08 34.9 0.0 2.1 2 0 0 2 2 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG65583.1 - 1.7e-07 31.8 0.0 4.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG65583.1 - 2.9e-07 30.3 0.1 0.00036 20.1 0.0 3.4 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG65583.1 - 1.2e-06 29.0 0.0 3.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG65583.1 - 2.6e-05 24.0 0.0 5.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65583.1 - 3.5e-05 23.6 0.0 8.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Tudor-knot PF11717.8 GBG65583.1 - 0.00029 20.6 0.0 0.00084 19.2 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Retrotrans_gag PF03732.17 GBG65583.1 - 0.11 12.7 0.0 1.5 9.2 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Integrin_b_cyt PF08725.11 GBG65583.1 - 0.12 12.1 0.1 6.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain SPT16 PF08644.11 GBG65584.1 - 6.7 6.9 6.9 1.2 9.3 2.2 2.1 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) RVT_1 PF00078.27 GBG65585.1 - 2.7e-26 92.5 0.0 4e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG65585.1 - 7.5e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65585.1 - 0.00011 22.8 0.0 0.00022 21.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65585.1 - 0.00029 21.3 0.0 0.00051 20.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG65585.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG65588.1 - 9.1e-23 80.9 0.1 1.6e-22 80.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65588.1 - 1.5e-14 53.8 0.2 1.5e-14 53.8 0.2 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG65588.1 - 2e-13 50.6 0.9 2e-12 47.3 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.24 GBG65588.1 - 1.7e-11 43.9 0.0 3.9e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG65588.1 - 0.00038 20.6 0.1 0.0009 19.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG65588.1 - 0.081 12.7 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain Thymidylat_synt PF00303.19 GBG65589.1 - 4.6e-67 226.0 0.0 2.3e-51 174.5 0.0 2.2 1 1 1 2 2 2 2 Thymidylate synthase DHFR_1 PF00186.19 GBG65589.1 - 4.8e-37 127.1 0.0 9.9e-37 126.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrofolate reductase Nop14 PF04147.12 GBG65589.1 - 0.21 9.8 14.9 0.046 12.0 6.9 2.2 2 0 0 2 2 2 0 Nop14-like family Tup_N PF08581.10 GBG65590.1 - 0.00056 20.2 0.3 0.0011 19.3 0.3 1.3 1 0 0 1 1 1 1 Tup N-terminal DHR10 PF18595.1 GBG65590.1 - 0.0013 18.8 0.2 0.0018 18.3 0.2 1.2 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain GreA_GreB_N PF03449.15 GBG65590.1 - 0.0048 17.0 0.4 0.012 15.7 0.4 1.7 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal Prefoldin_2 PF01920.20 GBG65590.1 - 0.0088 16.0 1.4 0.018 15.0 0.8 1.7 2 0 0 2 2 2 1 Prefoldin subunit DUF3450 PF11932.8 GBG65590.1 - 0.013 14.8 0.3 0.016 14.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AATF-Che1 PF13339.6 GBG65590.1 - 0.014 16.1 1.3 0.018 15.7 0.8 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Seryl_tRNA_N PF02403.22 GBG65590.1 - 0.028 14.6 3.1 0.17 12.2 3.1 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Sec2p PF06428.11 GBG65590.1 - 0.036 14.0 1.1 0.054 13.5 0.3 1.6 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DASH_Spc19 PF08287.11 GBG65590.1 - 0.057 13.3 1.0 0.075 12.9 1.0 1.2 1 0 0 1 1 1 0 Spc19 OmpH PF03938.14 GBG65590.1 - 0.06 13.7 3.7 0.1 12.9 3.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Leu_zip PF15294.6 GBG65590.1 - 0.072 12.6 1.4 0.09 12.3 1.3 1.3 1 1 0 1 1 1 0 Leucine zipper FlaC_arch PF05377.11 GBG65592.1 - 0.048 14.1 0.3 0.048 14.1 0.3 9.4 11 0 0 11 11 11 0 Flagella accessory protein C (FlaC) Atg8 PF02991.16 GBG65593.1 - 9.7e-52 173.5 0.1 1.1e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 GBG65593.1 - 2.3e-06 27.9 0.0 2.9e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2201 PF09967.9 GBG65593.1 - 0.14 12.3 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 VWA-like domain (DUF2201) SNRNP27 PF08648.12 GBG65594.1 - 1.4e-23 82.7 0.0 2.9e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Trypan_PARP PF05887.11 GBG65594.1 - 0.17 11.9 14.7 0.39 10.7 14.7 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) XS PF03468.14 GBG65595.1 - 2.6e-15 56.7 0.3 2.3e-13 50.5 0.0 3.1 2 0 0 2 2 2 1 XS domain zf-C3HC4_3 PF13920.6 GBG65595.1 - 3.5e-06 26.8 11.7 3.5e-06 26.8 11.7 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG65595.1 - 0.038 13.9 12.1 0.11 12.4 12.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 GBG65595.1 - 1.6 8.6 12.8 0.24 11.2 8.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 GBG65595.1 - 6.4 6.7 11.5 0.35 10.7 4.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AIG1 PF04548.16 GBG65597.1 - 3.3e-21 75.6 0.1 6.2e-21 74.7 0.1 1.5 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GBG65597.1 - 9.8e-12 45.0 0.0 1.5e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG65597.1 - 9.9e-09 35.3 0.1 1.5e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 GBG65597.1 - 1.1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 GBG65597.1 - 1.8e-05 25.2 0.6 0.00015 22.2 0.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 GBG65597.1 - 2.9e-05 23.5 0.1 6.1e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Septin Dynamin_N PF00350.23 GBG65597.1 - 0.00022 21.3 4.8 0.041 13.9 0.9 2.5 2 1 1 3 3 3 2 Dynamin family Sigma54_activat PF00158.26 GBG65597.1 - 0.004 16.9 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain NB-ARC PF00931.22 GBG65597.1 - 0.0064 15.7 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Gtr1_RagA PF04670.12 GBG65597.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 GBG65597.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG65597.1 - 0.066 13.8 0.2 5.7 7.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 GBG65597.1 - 0.076 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain IIGP PF05049.13 GBG65597.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 GBG65597.1 - 0.083 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 GBG65597.1 - 0.12 11.9 0.3 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 GBG65597.1 - 0.21 10.7 0.4 0.38 9.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mitofilin PF09731.9 GBG65598.1 - 5.4e-33 114.7 27.8 5.4e-33 114.7 27.8 3.2 3 0 0 3 3 3 1 Mitochondrial inner membrane protein Phage_lysozyme PF00959.19 GBG65599.1 - 0.32 11.5 0.0 0.32 11.5 0.0 2.9 3 1 1 4 4 4 0 Phage lysozyme zf-C3HC4_2 PF13923.6 GBG65600.1 - 2.1e-11 43.4 7.5 5e-11 42.3 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG65600.1 - 2.1e-08 34.4 8.7 6.9e-08 32.7 8.7 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG65600.1 - 5.8e-08 32.5 10.6 6.2e-08 32.4 8.9 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG65600.1 - 2.3e-05 24.2 12.7 7.3e-05 22.6 12.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG65600.1 - 0.00011 22.1 7.2 0.00031 20.7 7.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG65600.1 - 0.00014 21.8 10.2 0.00036 20.4 9.4 2.2 1 1 1 2 2 2 1 zinc-RING finger domain Retrotrans_gag PF03732.17 GBG65600.1 - 0.00075 19.7 3.3 0.0094 16.2 0.1 3.4 3 1 0 3 3 3 1 Retrotransposon gag protein zf-C3HC4_4 PF15227.6 GBG65600.1 - 0.0051 16.9 6.4 0.014 15.5 6.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING CENP-Q PF13094.6 GBG65600.1 - 0.016 15.4 8.1 0.03 14.5 8.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit USP8_interact PF08941.10 GBG65600.1 - 0.016 15.0 1.8 1.3 8.8 1.0 2.4 2 0 0 2 2 2 0 USP8 interacting zf-RING_4 PF14570.6 GBG65600.1 - 0.016 15.0 11.2 0.074 12.9 10.7 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 GBG65600.1 - 0.032 14.5 8.4 0.12 12.6 8.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GBG65600.1 - 0.052 13.4 11.3 2.8 7.9 11.2 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 gag-asp_proteas PF13975.6 GBG65600.1 - 0.057 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-C3HC4_5 PF17121.5 GBG65600.1 - 0.057 13.3 8.4 0.18 11.7 8.4 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GBG65600.1 - 0.12 12.3 5.1 0.24 11.3 5.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Spc7 PF08317.11 GBG65600.1 - 0.19 10.6 4.0 0.26 10.1 3.3 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 GBG65600.1 - 0.21 11.1 3.1 0.36 10.3 3.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MscS_porin PF12795.7 GBG65600.1 - 0.29 10.7 7.9 0.061 12.9 3.6 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ZapB PF06005.12 GBG65600.1 - 0.34 11.4 9.9 0.39 11.2 6.0 2.7 3 0 0 3 3 2 0 Cell division protein ZapB Sec2p PF06428.11 GBG65600.1 - 0.36 10.8 4.4 4.9 7.2 1.9 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p zf-Nse PF11789.8 GBG65600.1 - 0.39 10.6 6.2 0.94 9.4 6.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SlyX PF04102.12 GBG65600.1 - 0.47 11.1 6.0 0.66 10.6 1.1 3.2 3 0 0 3 3 3 0 SlyX PsbW PF07123.12 GBG65600.1 - 0.55 10.2 6.6 11 6.1 4.7 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) zf-RING_11 PF17123.5 GBG65600.1 - 0.66 9.8 7.6 0.47 10.2 4.9 2.3 2 0 0 2 2 2 0 RING-like zinc finger DivIC PF04977.15 GBG65600.1 - 0.88 9.4 3.4 0.84 9.5 0.8 2.1 2 0 0 2 2 2 0 Septum formation initiator zf-UDP PF14569.6 GBG65600.1 - 0.9 9.7 5.5 2.1 8.5 5.5 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_10 PF16685.5 GBG65600.1 - 1.6 8.9 7.9 3.5 7.8 7.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Spc24 PF08286.11 GBG65600.1 - 2.6 8.3 4.3 6.8 7.0 2.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Chromo PF00385.24 GBG65601.1 - 2.6e-05 24.0 0.5 5.4e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG65601.1 - 0.00048 20.3 2.6 0.0023 18.2 0.3 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein CENP-H PF05837.12 GBG65601.1 - 0.62 10.5 11.5 0.27 11.6 2.4 3.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 GBG65601.1 - 2.9 7.2 23.4 22 4.3 21.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Myb_DNA-bind_4 PF13837.6 GBG65602.1 - 0.00093 19.5 1.0 0.0095 16.3 0.1 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG65603.1 - 1.9e-24 86.1 0.0 4.6e-24 84.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65603.1 - 1.5e-12 47.5 0.0 2.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Retrotrans_gag PF03732.17 GBG65604.1 - 0.083 13.2 4.4 2.1 8.7 0.1 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein DUF4187 PF13821.6 GBG65604.1 - 0.096 12.5 1.6 0.3 10.9 1.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DDRGK PF09756.9 GBG65604.1 - 0.67 9.5 6.5 1.2 8.7 6.5 1.4 1 0 0 1 1 1 0 DDRGK domain RVT_1 PF00078.27 GBG65605.1 - 3.5e-23 82.3 0.1 8.3e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65605.1 - 3.7e-16 59.3 0.3 1.9e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65605.1 - 2.3e-10 40.4 0.4 9e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG65605.1 - 1.2e-06 28.3 0.0 3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65605.1 - 3e-06 27.8 0.0 7.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65605.1 - 0.0004 20.9 0.0 0.0013 19.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG65605.1 - 0.0013 18.8 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain WTX PF09422.10 GBG65605.1 - 0.0031 16.7 1.8 0.0048 16.0 1.8 1.2 1 0 0 1 1 1 1 WTX protein SlyX PF04102.12 GBG65605.1 - 0.042 14.5 6.3 1.1 9.9 0.6 3.7 4 0 0 4 4 4 0 SlyX DUF3492 PF11997.8 GBG65605.1 - 0.065 13.0 0.9 0.12 12.0 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) TolA_bind_tri PF16331.5 GBG65605.1 - 0.46 10.6 6.8 1.2 9.3 6.8 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation TRPM_tetra PF16519.5 GBG65605.1 - 7.2 6.8 5.8 33 4.7 0.2 3.8 4 0 0 4 4 4 0 Tetramerisation domain of TRPM TMEM107 PF14995.6 GBG65606.1 - 0.14 12.6 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein RVT_1 PF00078.27 GBG65607.1 - 1.2e-29 103.4 0.0 1.7e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG65608.1 - 1.1e-17 64.3 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Tetraspanin PF00335.20 GBG65609.1 - 9.4e-12 45.1 9.3 1.3e-11 44.6 2.5 2.1 1 1 1 2 2 2 2 Tetraspanin family DUF1449 PF07290.11 GBG65609.1 - 0.22 11.1 2.9 0.29 10.7 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1449) Myb_DNA-bind_4 PF13837.6 GBG65611.1 - 4.3e-12 46.2 3.4 4.3e-12 46.2 3.4 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG65611.1 - 0.083 13.1 1.5 0.15 12.3 1.5 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG65611.1 - 0.23 11.6 1.4 0.46 10.6 1.4 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Peptidase_M3 PF01432.20 GBG65612.1 - 1.8e-139 466.0 0.0 2.3e-139 465.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 GBG65612.1 - 0.011 15.3 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase M50B-like RT_RNaseH_2 PF17919.1 GBG65614.1 - 5.3e-32 109.8 0.0 9.3e-32 109.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65614.1 - 5e-31 107.9 0.0 7.3e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65614.1 - 2.3e-26 92.1 0.0 3.9e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG65614.1 - 0.37 11.0 2.5 0.73 10.0 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG65614.1 - 0.87 9.5 2.2 0.67 9.8 0.6 1.7 2 0 0 2 2 2 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG65616.1 - 3.4e-11 43.4 2.0 7.6e-11 42.2 2.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG65616.1 - 0.0014 18.6 1.5 0.0031 17.6 1.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG65616.1 - 0.0043 17.3 0.4 0.01 16.1 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG65616.1 - 0.083 13.2 0.3 0.083 13.2 0.3 2.1 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG65616.1 - 0.14 12.3 0.2 0.31 11.3 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain HSP70 PF00012.20 GBG65617.1 - 2.6e-96 323.2 4.2 4.4e-96 322.4 3.0 1.9 2 1 0 2 2 2 1 Hsp70 protein FGGY_C PF02782.16 GBG65617.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.13 GBG65617.1 - 0.031 13.1 0.1 0.073 11.9 0.1 1.5 1 0 0 1 1 1 0 MreB/Mbl protein EB_dh PF09459.10 GBG65618.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.7 1 1 0 1 1 1 0 Ethylbenzene dehydrogenase zf-CCHC PF00098.23 GBG65619.1 - 1.8e-06 27.7 1.5 2e-06 27.6 0.5 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG65619.1 - 0.016 15.0 0.7 0.03 14.1 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG65619.1 - 0.016 15.0 0.3 0.043 13.6 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle DNApol_Exo PF18136.1 GBG65619.1 - 0.19 10.9 1.0 0.26 10.4 1.0 1.4 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Fib_alpha PF08702.10 GBG65619.1 - 7.7 6.7 15.8 0.33 11.1 0.7 3.2 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family EB_dh PF09459.10 GBG65620.1 - 0.00031 20.8 0.0 0.0004 20.4 0.0 1.1 1 0 0 1 1 1 1 Ethylbenzene dehydrogenase RT_RNaseH PF17917.1 GBG65621.1 - 8.8e-21 74.2 0.0 1.8e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65621.1 - 3.7e-19 68.6 0.0 7.1e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65621.1 - 1.3e-12 47.6 0.1 3.2e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65621.1 - 3.3e-09 36.6 0.0 6.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG65621.1 - 2e-06 28.0 0.0 6.8e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG65621.1 - 0.031 14.5 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF659 PF04937.15 GBG65623.1 - 6.7e-34 117.0 0.0 9.2e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Glyco_hydro_17 PF00332.18 GBG65624.1 - 4.3e-66 223.6 0.0 5.8e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.13 GBG65624.1 - 1e-34 119.1 5.2 5.9e-20 71.7 0.1 2.9 3 0 0 3 3 3 2 X8 domain Nop53 PF07767.11 GBG65625.1 - 0.008 15.6 17.5 0.01 15.3 17.5 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF2828 PF11443.8 GBG65625.1 - 0.021 12.9 1.1 0.029 12.5 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Na_trans_assoc PF06512.13 GBG65625.1 - 0.055 13.8 11.7 0.083 13.2 11.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.14 GBG65625.1 - 1.3 7.2 16.1 1.6 6.9 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG65625.1 - 1.6 8.1 22.5 2 7.7 22.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG65625.1 - 7.5 4.6 27.2 1.8 6.7 24.1 1.4 2 0 0 2 2 2 0 Nop14-like family SURF2 PF05477.11 GBG65625.1 - 7.7 6.1 12.5 11 5.6 12.5 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Cwf_Cwc_15 PF04889.12 GBG65625.1 - 7.8 6.1 18.8 11 5.7 18.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein C2 PF00168.30 GBG65626.1 - 2.3e-07 31.0 0.0 3.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain gag-asp_proteas PF13975.6 GBG65627.1 - 3.2e-06 27.6 0.1 7.6e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65627.1 - 0.00031 21.3 0.1 0.00068 20.2 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65627.1 - 0.0099 15.7 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG65627.1 - 0.011 15.6 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG65627.1 - 0.024 14.3 0.3 0.048 13.3 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease_2 PF13650.6 GBG65628.1 - 6.8e-05 23.4 0.1 0.004 17.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65628.1 - 9e-05 23.0 0.1 0.0022 18.5 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease NOP19 PF10863.8 GBG65628.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Nucleolar protein 19 Retrotrans_gag PF03732.17 GBG65628.1 - 0.079 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4337 PF14235.6 GBG65629.1 - 6.2 6.9 10.9 4.2 7.5 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Laminin_G_3 PF13385.6 GBG65630.1 - 1.7e-68 229.6 7.8 1.4e-16 61.0 0.0 13.1 12 1 1 13 13 12 10 Concanavalin A-like lectin/glucanases superfamily Kelch_5 PF13854.6 GBG65630.1 - 2.9e-29 100.5 1.0 1.2e-06 28.4 0.1 6.9 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GBG65630.1 - 3.1e-27 94.3 5.7 1.5e-06 28.1 0.0 7.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GBG65630.1 - 1.4e-26 91.9 3.1 5.9e-07 29.6 0.0 6.3 5 0 0 5 5 5 5 Kelch motif Gal_Lectin PF02140.18 GBG65630.1 - 1.1e-22 80.3 0.7 2e-10 41.0 0.1 3.6 2 1 0 2 2 2 2 Galactose binding lectin domain Kelch_1 PF01344.25 GBG65630.1 - 3.2e-21 74.6 0.7 0.0027 17.3 0.0 6.2 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 GBG65630.1 - 2.1e-17 62.9 23.8 1.7e-05 25.0 0.0 8.0 7 0 0 7 7 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GBG65630.1 - 1.6e-13 50.0 4.8 0.038 14.0 0.0 6.7 6 0 0 6 6 6 4 Kelch motif TIG PF01833.24 GBG65630.1 - 8e-13 48.3 12.7 1.1e-05 25.4 0.2 7.0 7 0 0 7 7 7 3 IPT/TIG domain Filamin PF00630.19 GBG65630.1 - 2.9e-11 44.1 0.0 0.00022 22.0 0.0 3.4 3 0 0 3 3 3 2 Filamin/ABP280 repeat Laminin_G_2 PF02210.24 GBG65630.1 - 9.3e-10 39.2 0.0 0.48 11.0 0.0 7.3 8 0 0 8 8 7 2 Laminin G domain DUF2341 PF10102.9 GBG65630.1 - 1.2e-07 32.3 0.0 3.7e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2341) Invasin_D3 PF09134.10 GBG65630.1 - 0.00082 19.6 0.4 0.29 11.5 0.0 3.5 3 0 0 3 3 3 1 Invasin, domain 3 PA14 PF07691.12 GBG65630.1 - 0.00092 19.0 0.1 0.0043 16.9 0.0 2.2 2 0 0 2 2 2 1 PA14 domain Toxin_R_bind_N PF07953.12 GBG65630.1 - 0.0069 16.1 0.0 4.6 6.9 0.0 3.0 3 0 0 3 3 3 1 Clostridium neurotoxin, N-terminal receptor binding DUF2967 PF11179.8 GBG65631.1 - 0.017 13.3 4.8 0.018 13.2 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) BUD22 PF09073.10 GBG65631.1 - 0.019 14.3 16.6 0.024 14.0 16.6 1.1 1 0 0 1 1 1 0 BUD22 Na_trans_assoc PF06512.13 GBG65631.1 - 0.043 14.1 14.5 0.054 13.8 14.5 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Presenilin PF01080.17 GBG65631.1 - 0.086 11.6 7.8 0.095 11.4 7.8 1.1 1 0 0 1 1 1 0 Presenilin Swi6_N PF18530.1 GBG65631.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Swi6 N-terminal domain SAPS PF04499.15 GBG65631.1 - 0.3 9.8 4.0 0.38 9.5 4.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_11 PF13086.6 GBG65631.1 - 0.31 10.8 2.3 0.41 10.4 2.3 1.1 1 0 0 1 1 1 0 AAA domain FAM176 PF14851.6 GBG65631.1 - 0.88 9.2 22.0 1.2 8.8 4.2 2.2 2 0 0 2 2 2 0 FAM176 family Hid1 PF12722.7 GBG65631.1 - 0.92 7.6 3.1 1.1 7.3 3.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1770 PF08589.10 GBG65631.1 - 0.94 10.5 7.1 2.8 9.0 0.6 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) Prothymosin PF03247.14 GBG65631.1 - 1 9.8 42.3 3.5 8.1 25.4 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family Porph_ging PF09697.10 GBG65631.1 - 1.1 9.8 8.7 2.8 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) DUF5427 PF10310.9 GBG65631.1 - 1.6 7.6 16.4 0.12 11.4 0.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5427) RRN3 PF05327.11 GBG65631.1 - 8.7 4.8 11.8 11 4.4 11.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pes-10 PF07149.11 GBG65631.1 - 9.6 5.1 17.6 14 4.6 17.6 1.2 1 0 0 1 1 1 0 Pes-10 FrhB_FdhB_C PF04432.13 GBG65632.1 - 4.7e-33 114.2 0.0 8.3e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 GBG65632.1 - 1.7e-23 82.5 0.0 5e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Pec_lyase_C PF00544.19 GBG65633.1 - 1.8e-24 86.5 7.5 9.1e-24 84.2 7.5 1.9 1 1 0 1 1 1 1 Pectate lyase AP3D1 PF06375.11 GBG65633.1 - 9.3e-05 22.7 12.1 0.00016 21.9 12.1 1.3 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Beta_helix PF13229.6 GBG65633.1 - 0.0012 18.7 2.3 0.0038 17.1 2.3 1.8 1 1 0 1 1 1 1 Right handed beta helix region DNA_pol_phi PF04931.13 GBG65633.1 - 0.0015 16.7 14.6 0.0022 16.2 14.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 GBG65633.1 - 0.0017 17.8 17.3 0.0024 17.4 17.3 1.1 1 0 0 1 1 1 1 SDA1 RNA_pol_Rpc4 PF05132.14 GBG65633.1 - 0.0061 17.0 9.0 0.0061 17.0 9.0 1.7 2 0 0 2 2 1 1 RNA polymerase III RPC4 eIF3_subunit PF08597.10 GBG65633.1 - 0.0061 16.5 17.9 0.0095 15.9 17.9 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit SpoIIP PF07454.11 GBG65633.1 - 0.0091 15.5 8.1 0.015 14.8 8.1 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) BUD22 PF09073.10 GBG65633.1 - 0.0091 15.4 19.3 0.013 14.9 19.3 1.1 1 0 0 1 1 1 1 BUD22 RNA_pol_3_Rpc31 PF11705.8 GBG65633.1 - 0.0095 16.2 13.7 0.022 15.0 13.7 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Presenilin PF01080.17 GBG65633.1 - 0.0099 14.7 6.6 0.016 14.0 6.6 1.2 1 0 0 1 1 1 1 Presenilin CCSAP PF15748.5 GBG65633.1 - 0.016 15.4 7.9 0.016 15.4 7.9 1.5 2 0 0 2 2 1 0 Centriole, cilia and spindle-associated DDHD PF02862.17 GBG65633.1 - 0.018 15.2 1.1 0.029 14.5 1.1 1.3 1 0 0 1 1 1 0 DDHD domain DUF4746 PF15928.5 GBG65633.1 - 0.048 13.1 10.9 0.077 12.4 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAR2 PF05282.11 GBG65633.1 - 0.074 12.4 0.8 0.12 11.8 0.8 1.2 1 0 0 1 1 1 0 AAR2 protein DUF2126 PF09899.9 GBG65633.1 - 0.088 10.9 1.4 0.12 10.4 1.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SAPS PF04499.15 GBG65633.1 - 0.096 11.5 3.9 0.13 11.1 3.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ureide_permease PF07168.11 GBG65633.1 - 0.19 10.5 2.2 0.28 9.9 2.2 1.2 1 0 0 1 1 1 0 Ureide permease DUF1980 PF09323.10 GBG65633.1 - 0.19 11.6 1.2 0.42 10.5 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4820 PF16091.5 GBG65633.1 - 0.28 10.5 7.9 0.53 9.6 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TMEM214 PF10151.9 GBG65633.1 - 0.29 9.6 4.4 0.38 9.1 4.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DDRGK PF09756.9 GBG65633.1 - 0.34 10.5 22.8 0.65 9.6 22.8 1.4 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 GBG65633.1 - 0.34 10.7 16.6 0.57 10.0 16.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 GBG65633.1 - 0.42 10.7 19.5 0.67 10.1 19.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NPR3 PF03666.13 GBG65633.1 - 0.45 9.2 8.4 0.66 8.7 8.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 GBG65633.1 - 0.5 9.5 5.5 0.71 9.0 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pacifastin_I PF05375.13 GBG65633.1 - 0.51 10.1 1.5 0.87 9.4 1.5 1.4 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) Hid1 PF12722.7 GBG65633.1 - 0.56 8.3 3.6 0.71 7.9 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CPSF100_C PF13299.6 GBG65633.1 - 0.64 10.2 12.9 1.2 9.3 12.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 GBG65633.1 - 0.71 9.0 9.8 1.1 8.3 9.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Folate_carrier PF01770.18 GBG65633.1 - 0.85 8.3 2.6 1.5 7.5 2.6 1.3 1 0 0 1 1 1 0 Reduced folate carrier MCM_bind PF09739.9 GBG65633.1 - 0.89 7.9 7.4 1.2 7.5 7.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MDM10 PF12519.8 GBG65633.1 - 0.94 8.3 2.9 1.2 7.9 2.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FGF-BP1 PF06473.12 GBG65633.1 - 1.2 8.9 12.3 2.1 8.1 12.3 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) V_ATPase_I PF01496.19 GBG65633.1 - 1.7 6.5 10.6 2.3 6.0 10.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 GBG65633.1 - 1.7 7.5 8.7 2.7 6.9 8.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AIF_C PF14721.6 GBG65633.1 - 1.8 8.9 10.7 3.4 8.0 10.7 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RNA_polI_A34 PF08208.11 GBG65633.1 - 1.9 8.6 28.1 3.4 7.7 28.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 EIIBC-GUT_N PF03612.14 GBG65633.1 - 2 8.2 9.4 4.9 6.9 9.4 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus NARP1 PF12569.8 GBG65633.1 - 2.2 7.1 16.0 3.5 6.4 16.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Nop14 PF04147.12 GBG65633.1 - 2.6 6.2 25.0 3.6 5.7 25.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2828 PF11443.8 GBG65633.1 - 3.1 5.8 10.7 4.3 5.3 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PA26 PF04636.13 GBG65633.1 - 4.6 6.1 5.3 6.6 5.5 5.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Usp PF00582.26 GBG65633.1 - 4.6 7.7 9.0 9.3 6.8 9.0 1.4 1 0 0 1 1 1 0 Universal stress protein family Eapp_C PF10238.9 GBG65633.1 - 4.8 7.3 10.5 8.9 6.4 10.5 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein CobT PF06213.12 GBG65633.1 - 5.1 6.4 23.1 9.2 5.6 23.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CLN3 PF02487.17 GBG65633.1 - 5.3 6.0 4.7 8 5.4 4.7 1.2 1 0 0 1 1 1 0 CLN3 protein SLC12 PF03522.15 GBG65633.1 - 5.7 5.8 8.0 8.6 5.3 8.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TFIIF_alpha PF05793.12 GBG65633.1 - 6.7 5.2 31.4 11 4.5 31.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) KleE PF17394.2 GBG65634.1 - 0.18 12.0 0.1 0.57 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein gag-asp_proteas PF13975.6 GBG65635.1 - 1.4e-08 35.2 0.0 2.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65635.1 - 7.4e-07 29.7 0.0 1.6e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65635.1 - 2.9e-05 23.8 0.1 4.6e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65635.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG65635.1 - 0.69 10.1 1.9 1.3 9.3 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle PsbP PF01789.16 GBG65637.1 - 4.1e-30 105.0 0.0 6.4e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 PsbP RVT_1 PF00078.27 GBG65639.1 - 5.1e-10 39.2 0.2 7.8e-10 38.6 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65639.1 - 7.2e-09 35.6 0.1 1.4e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG65639.1 - 0.034 12.4 8.1 0.042 12.1 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG65639.1 - 0.072 11.4 9.2 0.091 11.0 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG65639.1 - 0.084 12.3 9.5 0.11 11.9 9.5 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG65639.1 - 0.19 11.2 4.4 0.29 10.7 4.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PTPRCAP PF15713.5 GBG65639.1 - 0.97 9.7 14.3 1.6 9.0 14.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Glyoxalase_4 PF13669.6 GBG65641.1 - 2.7e-14 53.4 0.0 3.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 GBG65641.1 - 1.9e-07 31.4 0.0 2.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 GBG65641.1 - 0.01 16.0 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Kinesin PF00225.23 GBG65642.1 - 1.8e-72 244.1 0.2 3.8e-72 243.0 0.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG65642.1 - 4.2e-10 39.8 0.0 8.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding ADIP PF11559.8 GBG65642.1 - 0.027 14.6 7.0 4.9 7.2 6.8 2.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CASP_C PF08172.12 GBG65642.1 - 0.044 13.1 5.9 0.13 11.5 5.9 1.9 1 0 0 1 1 1 0 CASP C terminal DUF4472 PF14739.6 GBG65642.1 - 0.075 13.8 6.9 0.47 11.2 6.9 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DUF724 PF05266.14 GBG65642.1 - 2.9 7.7 8.8 17 5.1 8.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.7 GBG65642.1 - 3.8 7.7 19.9 0.4 10.8 13.5 2.7 2 0 0 2 2 2 0 Tropomyosin like WD40_alt PF14077.6 GBG65642.1 - 8 6.4 7.0 7.7 6.5 0.2 3.4 2 1 1 3 3 3 0 Alternative WD40 repeat motif His_Phos_1 PF00300.22 GBG65643.1 - 2.7e-43 147.9 0.1 6.9e-43 146.6 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Sulfotransfer_2 PF03567.14 GBG65644.1 - 0.0024 17.8 1.5 0.016 15.1 0.0 2.8 4 0 0 4 4 4 1 Sulfotransferase family PPL5 PF18168.1 GBG65645.1 - 0.82 8.9 0.0 0.82 8.9 0.0 3.0 1 1 1 3 3 3 0 Prim-pol family 5 DUF659 PF04937.15 GBG65646.1 - 1.6e-39 135.2 0.3 3.7e-39 134.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65646.1 - 1.2e-05 24.9 0.0 3.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG65647.1 - 8.7e-36 123.5 0.0 1.4e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG65647.1 - 0.02 15.2 1.8 0.43 10.9 0.0 3.7 4 0 0 4 4 4 0 Retrotransposon gag protein RPAP3_C PF13877.6 GBG65648.1 - 1.7e-14 54.1 0.0 5.2e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 GBG65648.1 - 1.2e-09 37.5 0.4 0.0037 17.2 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG65648.1 - 1.3e-09 37.5 0.1 0.00034 20.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG65648.1 - 6.7e-07 29.9 2.7 0.0036 17.9 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG65648.1 - 6.9e-07 29.2 0.4 0.25 11.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG65648.1 - 1.7e-06 28.1 6.4 4.4e-06 26.7 2.3 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG65648.1 - 0.0012 19.3 1.0 0.028 14.9 0.1 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG65648.1 - 0.0012 19.5 4.5 0.02 15.7 1.2 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG65648.1 - 0.0014 18.3 0.1 0.2 11.4 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 GBG65648.1 - 0.0043 17.2 0.1 1.9 8.9 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG65648.1 - 0.1 12.9 1.0 0.25 11.7 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GBG65648.1 - 0.13 12.4 0.0 11 6.2 0.0 2.4 1 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Coatomer_WDAD PF04053.14 GBG65649.1 - 2.2e-157 524.7 0.0 4.8e-157 523.6 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 GBG65649.1 - 2.8e-38 129.2 10.7 4.2e-08 33.7 0.1 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG65649.1 - 2.8e-06 27.5 1.3 8 6.8 0.0 6.2 5 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 GBG65649.1 - 0.0095 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS Nup160 PF11715.8 GBG65649.1 - 0.071 11.7 0.4 13 4.3 0.1 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF2430 PF10353.9 GBG65649.1 - 0.083 13.3 0.0 3 8.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2430) TPR_12 PF13424.6 GBG65649.1 - 0.15 12.3 0.3 18 5.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 GBG65650.1 - 4.5e-17 62.3 0.0 1.6e-13 50.6 0.0 3.0 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_5 PF00266.19 GBG65650.1 - 0.0025 16.9 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Spc7 PF08317.11 GBG65654.1 - 1.7e-06 27.2 25.2 1.7e-06 27.2 25.2 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein O-antigen_lig PF13425.6 GBG65654.1 - 3.5 6.3 6.3 4.8 5.9 6.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FUSC PF04632.12 GBG65654.1 - 3.5 6.0 9.8 6.2 5.2 9.8 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3584 PF12128.8 GBG65654.1 - 5.1 4.5 28.6 2.5 5.5 26.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Helitron_like_N PF14214.6 GBG65654.1 - 6 7.0 8.8 25 5.0 8.8 2.1 1 1 0 1 1 1 0 Helitron helicase-like domain at N-terminus Troponin PF00992.20 GBG65654.1 - 8.9 6.6 33.3 1.8 8.9 26.2 2.5 1 1 1 2 2 2 0 Troponin Atg14 PF10186.9 GBG65654.1 - 9 5.3 18.2 15 4.6 18.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-CCHC_2 PF13696.6 GBG65656.1 - 0.0067 16.2 1.3 0.0099 15.7 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle Mer2 PF09074.10 GBG65656.1 - 0.076 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Mer2 Retrotrans_gag PF03732.17 GBG65656.1 - 0.1 12.9 0.2 0.25 11.7 0.2 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG65656.1 - 0.3 11.2 1.4 0.48 10.6 1.4 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG65657.1 - 2e-26 92.9 0.0 3.7e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65657.1 - 2.9e-19 68.9 0.1 6.2e-19 67.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG65657.1 - 6.6e-19 67.8 0.0 1.8e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65657.1 - 1.9e-17 63.5 0.1 8.2e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65657.1 - 5.6e-07 29.8 0.1 2.6e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG65657.1 - 0.00015 22.0 1.1 0.17 12.2 0.4 3.0 2 0 0 2 2 2 2 Retrotransposon gag protein DUF3727 PF12527.8 GBG65661.1 - 7e-11 42.2 0.1 7e-11 42.2 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3727) Pox_Ag35 PF03286.14 GBG65661.1 - 0.039 13.8 6.3 0.98 9.2 0.3 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 GBG65661.1 - 0.079 13.6 8.3 4.1 8.1 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) BSP_II PF05432.11 GBG65661.1 - 0.19 11.4 15.9 0.044 13.5 2.9 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 GBG65661.1 - 0.5 10.2 5.2 0.59 10.0 1.8 2.0 2 0 0 2 2 2 0 Myc amino-terminal region FAM176 PF14851.6 GBG65661.1 - 0.68 9.6 8.7 4.7 6.9 0.3 2.2 2 0 0 2 2 2 0 FAM176 family DUF4637 PF15470.6 GBG65661.1 - 8.9 6.0 11.7 0.44 10.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) TRAP_alpha PF03896.16 GBG65661.1 - 9.4 5.3 5.8 20 4.3 1.9 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Phage_Nu1 PF07471.12 GBG65662.1 - 0.11 12.3 6.3 0.22 11.3 6.3 1.5 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Cep57_CLD_2 PF14197.6 GBG65662.1 - 0.21 11.7 7.9 4.4 7.5 7.9 2.7 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 HMG_box_5 PF14887.6 GBG65663.1 - 0.038 13.9 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 SGT1 PF07093.11 GBG65663.1 - 0.73 8.2 10.0 1.3 7.3 10.0 1.4 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.12 GBG65663.1 - 8.9 4.4 28.1 0.0084 14.4 16.1 1.8 2 0 0 2 2 2 0 Nop14-like family Dimer_Tnp_hAT PF05699.14 GBG65664.1 - 0.00011 21.9 0.2 0.0002 21.0 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DivIC PF04977.15 GBG65665.1 - 0.1 12.4 2.1 0.11 12.3 0.1 2.1 3 0 0 3 3 3 0 Septum formation initiator Sororin PF09666.10 GBG65665.1 - 0.11 12.7 1.1 6.3 7.0 0.2 2.5 1 1 1 3 3 3 0 Sororin protein HALZ PF02183.18 GBG65665.1 - 0.3 11.3 3.6 0.18 12.0 0.9 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 GBG65665.1 - 0.62 10.7 2.9 27 5.5 0.1 3.1 1 1 1 2 2 2 0 Initiation control protein YabA Tub_N PF16322.5 GBG65665.1 - 8.9 6.7 11.5 31 4.9 11.5 1.8 1 1 0 1 1 1 0 Tubby N-terminal WD40 PF00400.32 GBG65668.1 - 2.3e-12 47.2 4.7 0.00085 20.1 0.0 6.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG65668.1 - 0.00026 21.2 0.0 11 6.4 0.0 3.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG65668.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 WD40-like domain Pkinase PF00069.25 GBG65668.1 - 0.0018 17.7 0.0 0.051 12.9 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG65668.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein tyrosine kinase BTG PF07742.12 GBG65668.1 - 0.22 11.4 2.0 0.69 9.8 2.0 1.8 1 0 0 1 1 1 0 BTG family RVT_1 PF00078.27 GBG65669.1 - 9e-21 74.4 0.0 1.8e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65669.1 - 1.2e-14 54.1 0.2 4.7e-14 52.2 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65669.1 - 1.3e-10 41.5 0.0 3.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG65669.1 - 0.0054 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG65669.1 - 0.045 14.0 0.2 0.045 14.0 0.2 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Caudo_TAP PF02413.17 GBG65669.1 - 0.57 10.3 8.8 0.7 10.1 1.8 3.0 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Oleosin PF01277.17 GBG65671.1 - 5.6e-10 39.0 4.5 5.6e-10 39.0 4.5 2.0 2 0 0 2 2 2 1 Oleosin ABC2_membrane_3 PF12698.7 GBG65671.1 - 0.063 12.4 6.0 0.1 11.7 6.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein AMP-binding PF00501.28 GBG65673.1 - 4e-88 295.8 0.0 4.7e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Mito_carr PF00153.27 GBG65674.1 - 2.7e-19 68.9 0.1 5.5e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial carrier protein rve PF00665.26 GBG65674.1 - 3e-11 43.5 0.0 5.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG65674.1 - 1.1e-05 25.5 0.0 3.1e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG65674.1 - 0.0047 16.7 0.0 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG65674.1 - 0.013 15.3 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FAM199X PF15814.5 GBG65676.1 - 1 8.3 7.4 1.7 7.6 7.4 1.3 1 0 0 1 1 1 0 Protein family FAM199X EF-1_beta_acid PF10587.9 GBG65677.1 - 2.4 8.7 0.0 2.4 8.7 0.0 6.1 4 2 0 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region Nop14 PF04147.12 GBG65677.1 - 3.9 5.6 26.7 4.7 5.3 26.7 1.1 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 GBG65678.1 - 0.0047 16.9 2.7 0.0047 16.9 2.7 2.9 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) RAP1 PF07218.11 GBG65678.1 - 0.016 13.5 0.3 0.023 13.0 0.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Bcr-Abl_Oligo PF09036.10 GBG65678.1 - 0.028 14.4 1.8 0.22 11.6 0.0 3.2 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DUF4407 PF14362.6 GBG65678.1 - 0.13 11.6 25.0 0.04 13.3 5.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Jun PF03957.13 GBG65678.1 - 1.5 8.7 6.3 1.4 8.7 0.4 2.4 2 0 0 2 2 2 0 Jun-like transcription factor SelK_SelG PF10961.8 GBG65678.1 - 2.4 8.8 17.8 12 6.6 0.8 3.6 3 0 0 3 3 3 0 Selenoprotein SelK_SelG ATG16 PF08614.11 GBG65678.1 - 2.4 8.3 37.5 0.81 9.9 0.7 5.6 5 1 0 5 5 5 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 GBG65678.1 - 3.8 7.9 27.7 1.3 9.5 4.8 3.9 2 1 0 2 2 2 0 Fez1 tRNA-synt_1 PF00133.22 GBG65679.1 - 2.4e-21 75.6 1.3 9e-20 70.5 1.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GBG65679.1 - 7.4e-16 57.9 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GBG65680.1 - 8.9e-21 74.4 0.2 5.2e-20 72.0 0.2 2.0 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 GBG65680.1 - 2.3e-15 55.9 0.0 1.7e-07 29.9 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 GBG65680.1 - 1.8e-12 47.1 0.0 3.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 GBG65680.1 - 9.4e-05 21.3 0.0 0.00023 20.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 GBG65680.1 - 0.049 12.6 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 GBG65680.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain JAB PF01398.21 GBG65681.1 - 8.6e-23 80.6 0.0 1.3e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GBG65681.1 - 3.7e-22 78.8 0.0 6e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function LRR_4 PF12799.7 GBG65682.1 - 2.9e-11 43.4 18.9 0.00015 22.0 3.7 3.6 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GBG65682.1 - 3.7e-08 33.1 3.8 5.1e-08 32.6 3.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 GBG65682.1 - 7e-06 25.7 25.6 0.00012 21.8 8.5 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 GBG65682.1 - 0.14 12.3 8.6 34 4.8 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich repeat Myc_N PF01056.18 GBG65682.1 - 3.9 7.3 13.1 6.4 6.6 2.1 2.2 2 0 0 2 2 2 0 Myc amino-terminal region MFS_1 PF07690.16 GBG65685.1 - 4.7e-18 65.3 35.7 2.2e-10 40.0 7.2 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Mito_fiss_reg PF05308.11 GBG65685.1 - 0.14 12.3 8.9 0.6 10.2 1.7 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator CtaG_Cox11 PF04442.14 GBG65686.1 - 3.4e-60 202.4 0.1 5.3e-60 201.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 vATP-synt_E PF01991.18 GBG65687.1 - 1.2e-64 217.4 0.2 1.4e-64 217.2 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Folliculin PF11704.8 GBG65687.1 - 3 7.7 8.0 7.7 6.4 8.0 1.6 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport YjbH PF06082.11 GBG65687.1 - 4.1 6.1 5.4 4.8 5.9 5.4 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH RVT_1 PF00078.27 GBG65688.1 - 4.8e-29 101.5 0.0 7.9e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65688.1 - 4e-14 52.5 2.6 1e-13 51.2 0.0 2.9 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG65688.1 - 2.2e-11 44.0 0.0 5.4e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65688.1 - 2e-05 24.7 0.0 5.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG65689.1 - 1.1e-09 38.5 0.3 3.5e-09 36.9 0.3 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG65689.1 - 0.043 14.1 0.2 0.078 13.3 0.2 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG65690.1 - 1.9e-08 34.1 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65690.1 - 0.0064 16.1 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG65690.1 - 0.071 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain Connexin PF00029.19 GBG65691.1 - 0.00032 20.5 8.6 0.00054 19.8 8.6 1.3 1 0 0 1 1 1 1 Connexin RNA_pol_3_Rpc31 PF11705.8 GBG65691.1 - 0.00045 20.5 18.3 0.00053 20.3 18.3 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PPL5 PF18168.1 GBG65691.1 - 0.00068 19.0 4.5 0.00097 18.5 4.5 1.2 1 0 0 1 1 1 1 Prim-pol family 5 AAA_23 PF13476.6 GBG65691.1 - 0.0013 19.3 14.6 0.0014 19.2 14.6 1.2 1 0 0 1 1 1 1 AAA domain SID-1_RNA_chan PF13965.6 GBG65691.1 - 0.0014 17.1 1.0 0.0014 17.1 1.0 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Nop14 PF04147.12 GBG65691.1 - 0.004 15.4 19.3 0.004 15.4 19.3 1.1 1 0 0 1 1 1 1 Nop14-like family RNA_pol_Rpc4 PF05132.14 GBG65691.1 - 0.0064 16.9 7.9 0.0099 16.3 7.9 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 CDC45 PF02724.14 GBG65691.1 - 0.01 14.2 15.5 0.012 13.9 15.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 GBG65691.1 - 0.01 14.7 10.4 0.01 14.7 10.4 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 GBG65691.1 - 0.027 13.4 6.0 0.028 13.4 6.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 GBG65691.1 - 0.031 14.5 11.0 0.053 13.7 11.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 GBG65691.1 - 0.032 14.4 5.0 0.036 14.2 5.0 1.2 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.15 GBG65691.1 - 0.034 13.1 3.4 0.035 13.0 3.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 GBG65691.1 - 0.055 11.4 10.9 0.065 11.1 10.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 GBG65691.1 - 0.06 12.4 5.0 0.061 12.3 5.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 GBG65691.1 - 0.068 12.0 8.5 0.069 11.9 8.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CBP_BcsG PF11658.8 GBG65691.1 - 0.069 11.5 0.1 0.09 11.2 0.1 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF5308 PF17233.2 GBG65691.1 - 0.08 13.2 2.3 0.11 12.7 2.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF2828 PF11443.8 GBG65691.1 - 0.095 10.8 7.1 0.085 10.9 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Borrelia_P83 PF05262.11 GBG65691.1 - 0.12 10.9 17.2 0.14 10.6 17.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein BUD22 PF09073.10 GBG65691.1 - 0.13 11.6 22.7 0.17 11.2 22.7 1.2 1 0 0 1 1 1 0 BUD22 CLN3 PF02487.17 GBG65691.1 - 0.15 11.1 4.2 0.19 10.7 4.2 1.1 1 0 0 1 1 1 0 CLN3 protein Rxt3 PF08642.10 GBG65691.1 - 0.18 12.6 4.6 0.34 11.7 4.6 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Ureide_permease PF07168.11 GBG65691.1 - 0.2 10.4 3.4 0.22 10.3 3.4 1.2 1 0 0 1 1 1 0 Ureide permease Na_trans_assoc PF06512.13 GBG65691.1 - 0.27 11.5 17.1 0.33 11.2 17.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated TRAP_alpha PF03896.16 GBG65691.1 - 0.35 10.0 13.5 0.49 9.6 13.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit O-antigen_lig PF13425.6 GBG65691.1 - 0.37 9.5 5.0 0.41 9.4 5.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein OATP PF03137.20 GBG65691.1 - 0.44 8.8 3.1 0.53 8.5 3.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Hid1 PF12722.7 GBG65691.1 - 0.49 8.5 6.6 0.41 8.7 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CobT PF06213.12 GBG65691.1 - 0.6 9.5 28.5 0.92 8.8 28.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Neur_chan_memb PF02932.16 GBG65691.1 - 0.74 9.8 4.4 0.88 9.6 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2201_N PF13203.6 GBG65691.1 - 0.81 9.2 6.7 0.75 9.3 6.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain TMEM214 PF10151.9 GBG65691.1 - 0.89 7.9 7.2 0.78 8.1 7.2 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator CSG2 PF16965.5 GBG65691.1 - 0.96 8.3 2.4 0.9 8.4 2.4 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2151 PF10221.9 GBG65691.1 - 1.1 7.7 11.3 1.5 7.3 11.3 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator AIF_C PF14721.6 GBG65691.1 - 1.3 9.4 12.2 0.71 10.2 10.1 1.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SDA1 PF05285.12 GBG65691.1 - 1.3 8.4 29.3 2 7.7 29.3 1.3 1 0 0 1 1 1 0 SDA1 Afi1 PF07792.12 GBG65691.1 - 1.3 9.5 19.5 1.9 9.0 18.8 1.5 1 1 1 2 2 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RAB3GAP2_C PF14656.6 GBG65691.1 - 1.4 7.0 9.3 1.9 6.6 9.3 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus ALMT PF11744.8 GBG65691.1 - 1.4 7.6 5.7 1.8 7.3 5.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PA26 PF04636.13 GBG65691.1 - 1.5 7.7 6.2 1.4 7.7 6.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Folate_carrier PF01770.18 GBG65691.1 - 1.6 7.4 4.6 2 7.0 4.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier FGF-BP1 PF06473.12 GBG65691.1 - 2.3 8.0 16.2 0.41 10.4 13.2 1.3 2 0 0 2 2 1 0 FGF binding protein 1 (FGF-BP1) DUF3306 PF11748.8 GBG65691.1 - 2.3 9.1 15.4 0.47 11.3 12.3 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3306) DUF789 PF05623.12 GBG65691.1 - 2.3 7.8 6.9 3.1 7.4 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Usp PF00582.26 GBG65691.1 - 2.8 8.4 12.3 0.98 9.9 10.0 1.5 2 0 0 2 2 1 0 Universal stress protein family DUF2428 PF10350.9 GBG65691.1 - 3 7.0 7.8 4.8 6.4 7.8 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) DUF2514 PF10721.9 GBG65691.1 - 3.4 7.7 9.8 0.29 11.1 5.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DUF4820 PF16091.5 GBG65691.1 - 3.7 6.9 20.0 16 4.7 20.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) ATP-synt_E PF05680.12 GBG65691.1 - 3.7 8.0 18.2 3 8.2 15.1 2.0 2 0 0 2 2 2 0 ATP synthase E chain Mem_trans PF03547.18 GBG65691.1 - 4.3 5.6 5.1 5.7 5.2 5.1 1.2 1 0 0 1 1 1 0 Membrane transport protein EIIBC-GUT_N PF03612.14 GBG65691.1 - 6.6 6.4 12.8 1.6 8.4 9.8 1.5 2 0 0 2 2 1 0 Sorbitol phosphotransferase enzyme II N-terminus YqfQ PF14181.6 GBG65691.1 - 6.7 6.9 16.3 10 6.3 16.3 1.3 1 0 0 1 1 1 0 YqfQ-like protein Dynamin_N PF00350.23 GBG65691.1 - 9.3 6.3 8.7 12 5.9 8.7 1.4 1 1 0 1 1 1 0 Dynamin family Ycf1 PF05758.12 GBG65691.1 - 10 3.9 10.1 12 3.6 10.1 1.1 1 0 0 1 1 1 0 Ycf1 Beta_helix PF13229.6 GBG65692.1 - 0.001 19.0 12.0 0.048 13.5 9.4 2.8 2 1 0 2 2 2 1 Right handed beta helix region RVT_1 PF00078.27 GBG65693.1 - 3.9e-16 59.3 0.0 8.6e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65694.1 - 1.1e-14 54.3 0.1 1.1e-14 54.3 0.1 3.0 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG65694.1 - 8.8e-13 48.5 0.0 2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG65694.1 - 9.1e-10 38.3 0.0 1.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG65694.1 - 8.8e-06 25.8 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG65696.1 - 1.7e-27 96.4 0.1 3e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65696.1 - 2.5e-19 69.1 0.0 1.9e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65696.1 - 1.7e-15 56.9 1.6 3.9e-15 55.7 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG65696.1 - 4.8e-12 45.6 0.0 9.5e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG65696.1 - 1.1e-08 35.2 0.0 3.8e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG65696.1 - 1.4e-07 31.8 0.0 3.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG65696.1 - 9.4e-05 22.5 0.0 0.00022 21.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG65697.1 - 4.9e-08 32.7 4.5 1.3e-07 31.3 4.5 1.8 1 0 0 1 1 1 1 Zinc knuckle GIY-YIG PF01541.24 GBG65697.1 - 0.00018 21.7 0.0 0.00043 20.5 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain C2 PF00168.30 GBG65698.1 - 2.5e-08 34.2 0.0 4.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain Dynein_light PF01221.18 GBG65699.1 - 2.2e-19 69.5 0.4 2.8e-19 69.2 0.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 GST_N_3 PF13417.6 GBG65701.1 - 8e-21 74.2 0.0 1.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GBG65701.1 - 1.4e-15 57.4 0.0 2.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG65701.1 - 3.9e-14 52.7 0.0 7.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GBG65701.1 - 1.3e-05 25.4 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 GBG65701.1 - 0.00012 22.3 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GBG65701.1 - 0.00019 22.0 0.0 0.0003 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GBG65701.1 - 0.00036 20.5 0.0 0.00059 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase_Tyr PF07714.17 GBG65702.1 - 2.1e-28 99.3 0.0 4.2e-28 98.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG65702.1 - 1.2e-26 93.7 0.0 1.6e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 GBG65702.1 - 3.4e-06 26.7 1.8 7.2e-06 25.7 1.8 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GBG65702.1 - 0.00041 20.7 3.6 0.00097 19.5 3.6 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG65702.1 - 0.0097 16.3 4.0 0.76 10.6 0.1 3.4 2 1 0 2 2 2 1 Leucine Rich Repeat DAP10 PF07213.11 GBG65702.1 - 0.057 13.4 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 DAP10 membrane protein Malectin PF11721.8 GBG65703.1 - 0.003 17.7 0.0 0.052 13.6 0.0 2.3 2 0 0 2 2 2 1 Malectin domain Retrotrans_gag PF03732.17 GBG65704.1 - 0.0052 17.0 0.6 0.0095 16.2 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein LRR_4 PF12799.7 GBG65705.1 - 4.6e-07 30.1 2.1 1e-06 29.0 2.1 1.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG65705.1 - 3.2e-06 26.8 3.2 4.7e-06 26.3 3.2 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 GBG65705.1 - 0.022 15.2 4.7 0.46 11.2 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat SARAF PF06682.12 GBG65705.1 - 0.11 12.1 2.3 5.5 6.5 0.0 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Ribosomal_60s PF00428.19 GBG65705.1 - 0.2 12.3 6.2 0.35 11.5 6.2 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Malectin_like PF12819.7 GBG65706.1 - 7.6e-12 45.0 0.0 1.1e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 Malectin-like domain Malectin PF11721.8 GBG65706.1 - 1.3e-06 28.6 0.0 3.6e-05 23.9 0.0 2.7 2 1 0 2 2 2 1 Malectin domain JmjC PF02373.22 GBG65707.1 - 0.0092 16.4 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase GIY-YIG PF01541.24 GBG65708.1 - 8.2e-05 22.8 0.0 0.00039 20.6 0.0 2.1 2 0 0 2 2 2 1 GIY-YIG catalytic domain Integrase_H2C2 PF17921.1 GBG65709.1 - 2.9e-18 65.7 1.3 7.4e-18 64.4 1.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65709.1 - 2.9e-16 59.7 0.0 9.8e-16 58.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG65709.1 - 9.5e-15 54.8 0.0 2.7e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65709.1 - 7.6e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG65709.1 - 1.2e-06 29.0 0.0 2.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65709.1 - 5.2e-05 23.8 0.1 0.00014 22.5 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65709.1 - 0.0023 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65709.1 - 0.02 14.7 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG65709.1 - 0.04 13.6 0.3 0.11 12.2 0.3 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG65709.1 - 0.27 11.4 1.6 0.67 10.1 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Pox_MCEL PF03291.16 GBG65710.1 - 1.2e-14 54.2 0.0 2.9e-06 26.7 0.0 2.0 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 GBG65710.1 - 1.5e-08 35.2 0.2 4.7e-07 30.4 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG65710.1 - 5.4e-08 33.4 0.0 5.4e-07 30.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG65710.1 - 4.7e-07 29.7 0.1 1.8e-06 27.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG65710.1 - 5.6e-06 26.3 0.1 1.3e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG65710.1 - 7e-06 26.7 0.1 0.00025 21.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 GBG65710.1 - 0.0036 17.1 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 2 DNA methylase Ndufs5 PF10200.9 GBG65710.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.5 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa TPMT PF05724.11 GBG65710.1 - 0.027 14.1 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 GBG65710.1 - 0.039 13.5 0.0 1.6 8.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 GBG65710.1 - 0.083 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 GBG65710.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 GBG65710.1 - 0.18 11.1 0.0 0.68 9.2 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family RVT_1 PF00078.27 GBG65711.1 - 8.4e-36 123.5 0.1 1.4e-35 122.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65711.1 - 2.2e-19 69.7 0.2 5.9e-19 68.3 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65711.1 - 4.2e-10 39.6 0.0 1.2e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gpUL132 PF11359.8 GBG65711.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Es2 PF09751.9 GBG65711.1 - 7.2 6.2 17.5 13 5.4 17.5 1.3 1 0 0 1 1 1 0 Nuclear protein Es2 RT_RNaseH PF17917.1 GBG65714.1 - 6e-20 71.5 0.0 1.3e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65714.1 - 3.9e-19 68.5 0.0 1e-18 67.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65714.1 - 1.2e-12 47.7 0.3 2.9e-12 46.5 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain USP8_interact PF08941.10 GBG65714.1 - 0.033 14.0 2.3 0.092 12.6 2.3 1.8 1 0 0 1 1 1 0 USP8 interacting zf-H2C2 PF09337.10 GBG65714.1 - 0.058 13.6 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Pep_deformylase PF01327.21 GBG65714.1 - 0.16 11.6 1.7 0.4 10.3 1.7 1.6 1 0 0 1 1 1 0 Polypeptide deformylase zf-CCHC PF00098.23 GBG65714.1 - 1.1 9.5 14.4 1.5 9.0 2.5 2.5 2 0 0 2 2 2 0 Zinc knuckle TMF_TATA_bd PF12325.8 GBG65714.1 - 2.9 8.1 18.6 0.094 12.9 4.8 3.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-CCHC_5 PF14787.6 GBG65714.1 - 9.8 6.0 14.7 0.044 13.5 4.3 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Dimer_Tnp_hAT PF05699.14 GBG65715.1 - 0.032 14.0 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Vac7 PF12751.7 GBG65715.1 - 0.15 11.5 15.2 0.27 10.7 15.2 1.4 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 ATG16 PF08614.11 GBG65716.1 - 0.05 13.8 8.3 0.046 14.0 7.1 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 GBG65717.1 - 0.051 13.9 0.4 1.3 9.4 0.1 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) SSFA2_C PF14723.6 GBG65717.1 - 0.89 9.4 4.5 3.1 7.7 2.6 2.5 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus RVP_2 PF08284.11 GBG65718.1 - 0.057 13.2 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG65718.1 - 0.28 11.3 0.7 0.62 10.2 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle SAC3_GANP PF03399.16 GBG65719.1 - 3.8e-91 305.5 2.5 3.8e-91 305.5 2.5 1.6 2 0 0 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GBG65719.1 - 0.032 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TFIID-31kDa PF02291.15 GBG65720.1 - 1.2e-48 164.2 0.1 1.5e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GBG65720.1 - 9.7e-08 31.9 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 GBG65720.1 - 4.8e-05 23.7 0.1 7.3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 GBG65720.1 - 0.00022 21.6 0.6 0.00032 21.0 0.1 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GBG65720.1 - 0.00077 19.5 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_30kDa PF03540.13 GBG65720.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Neisseria_TspB PF05616.13 GBG65720.1 - 0.21 10.0 0.9 0.26 9.7 0.9 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RVT_1 PF00078.27 GBG65721.1 - 4.6e-20 72.1 0.1 6.3e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCDC85 PF10226.9 GBG65722.1 - 0.0027 17.4 0.1 0.0058 16.3 0.1 1.5 1 0 0 1 1 1 1 CCDC85 family DUF2385 PF09539.10 GBG65722.1 - 0.017 15.6 0.8 0.7 10.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) HCV_NS5a_C PF12941.7 GBG65722.1 - 0.12 12.3 4.7 0.21 11.4 4.7 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region DUF281 PF03436.13 GBG65722.1 - 2.6 8.5 6.0 5.9 7.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF281) ABC_tran_CTD PF16326.5 GBG65722.1 - 2.7 8.3 9.3 0.14 12.5 0.9 3.0 2 1 1 3 3 3 0 ABC transporter C-terminal domain Integrase_H2C2 PF17921.1 GBG65723.1 - 1.6e-12 47.4 1.3 3.5e-12 46.2 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65723.1 - 4.6e-08 32.8 0.0 8.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG65723.1 - 2.5e-06 27.9 0.0 5.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG65723.1 - 1.6e-05 25.1 0.0 3.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG65723.1 - 3.8e-05 24.3 0.0 8.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65723.1 - 0.00058 19.6 0.7 0.0012 18.7 0.7 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG65723.1 - 0.036 14.4 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG65723.1 - 0.89 9.7 9.8 0.5 10.6 0.7 2.9 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG65724.1 - 4.5e-09 36.7 0.0 1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65724.1 - 2.9e-06 27.8 0.0 6.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65724.1 - 0.00016 21.5 0.7 0.00029 20.6 0.7 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG65724.1 - 0.00051 20.3 0.0 0.0012 19.1 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease CDC45 PF02724.14 GBG65724.1 - 1.4 7.2 3.8 1.7 6.8 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Histone PF00125.24 GBG65725.1 - 9.5e-21 74.5 2.5 9.5e-21 74.5 2.5 2.6 4 0 0 4 4 4 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG65725.1 - 0.00025 21.2 0.1 0.00025 21.2 0.1 2.9 3 1 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GBG65725.1 - 0.0066 16.9 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1804 PF08822.11 GBG65725.1 - 0.038 14.0 4.9 1.8 8.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) DUF1192 PF06698.11 GBG65725.1 - 4.1 7.5 10.7 0.16 12.1 2.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) RVT_1 PF00078.27 GBG65726.1 - 1.1e-27 97.0 0.0 1.6e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG65726.1 - 7.4e-09 35.4 0.0 1.7e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG65726.1 - 0.017 15.7 0.0 0.043 14.5 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Histone PF00125.24 GBG65727.1 - 1e-21 77.7 2.8 1.2e-21 77.5 2.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG65727.1 - 3.2e-05 24.1 0.1 3.2e-05 24.1 0.1 2.2 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GBG65727.1 - 0.0011 19.4 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 GBG65727.1 - 0.0042 17.2 3.0 0.0051 16.9 3.0 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 GBG65727.1 - 0.012 15.3 0.3 1.7 8.3 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Hydant_A_N PF05378.13 GBG65727.1 - 0.055 13.2 0.1 0.079 12.7 0.1 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region SLC12 PF03522.15 GBG65728.1 - 7.8 5.4 5.8 10 5.0 5.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 TIP49 PF06068.13 GBG65729.1 - 1.1e-168 561.0 0.1 1.3e-168 560.7 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GBG65729.1 - 3.1e-20 72.1 0.0 8.9e-20 70.6 0.0 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 GBG65729.1 - 2.3e-10 41.0 0.2 2.1e-06 28.2 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GBG65729.1 - 5.9e-10 39.1 0.2 2.3e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG65729.1 - 2.1e-06 28.0 0.4 0.0051 17.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 GBG65729.1 - 0.00074 19.9 3.1 0.024 15.0 3.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG65729.1 - 0.0011 19.4 0.1 0.017 15.5 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GBG65729.1 - 0.0015 18.6 0.1 0.22 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 GBG65729.1 - 0.0031 17.8 0.3 0.0084 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 GBG65729.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 GBG65729.1 - 0.014 14.8 0.2 0.82 9.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GBG65729.1 - 0.017 14.7 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GBG65729.1 - 0.027 14.2 0.1 9.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 GBG65729.1 - 0.028 13.7 0.3 0.073 12.3 0.3 1.7 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 GBG65729.1 - 0.037 14.0 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GBG65729.1 - 0.042 13.8 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 GBG65729.1 - 0.055 12.7 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 GBG65729.1 - 0.077 12.7 0.6 2.6 7.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 GBG65729.1 - 0.15 11.8 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Arm PF00514.23 GBG65731.1 - 2.4e-35 119.5 10.8 1.4e-05 25.0 0.0 8.6 8 0 0 8 8 8 7 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 GBG65731.1 - 6.1e-08 32.1 1.1 1.3e-07 31.0 1.1 1.4 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 GBG65731.1 - 1e-05 25.4 1.8 0.26 11.7 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 GBG65731.1 - 0.0003 21.1 8.7 0.31 11.5 0.7 4.6 3 2 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 GBG65731.1 - 0.0068 16.9 0.5 0.0068 16.9 0.5 6.0 5 3 3 8 8 8 2 HEAT-like repeat IFRD PF05004.13 GBG65731.1 - 0.018 14.2 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Topo_Zn_Ribbon PF08272.11 GBG65732.1 - 0.054 13.2 0.2 0.15 11.7 0.2 1.8 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG65732.1 - 0.24 11.5 1.9 0.4 10.9 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RNA_pol_Rpb1_R PF05001.13 GBG65734.1 - 0.033 14.5 0.6 0.033 14.5 0.6 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat RRM_1 PF00076.22 GBG65736.1 - 1.1e-18 66.8 0.1 2e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 GBG65737.1 - 4.5 6.4 10.6 5.5 6.1 10.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SOG2 PF10428.9 GBG65738.1 - 3.7 6.7 10.6 4.4 6.4 10.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_S11 PF00411.19 GBG65739.1 - 1e-47 161.0 1.1 1.3e-47 160.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 GBG65739.1 - 0.051 13.8 0.1 0.13 12.5 0.0 1.7 2 1 0 2 2 2 0 Carbohydrate binding domain (family 25) Ribosomal_L18p PF00861.22 GBG65739.1 - 0.083 13.3 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast RepB-RCR_reg PF10723.9 GBG65740.1 - 0.023 14.6 6.8 0.27 11.2 2.6 2.8 2 1 0 2 2 2 0 Replication regulatory protein RepB SecA_PP_bind PF01043.20 GBG65740.1 - 0.1 13.2 3.4 0.22 12.2 3.4 1.6 1 0 0 1 1 1 0 SecA preprotein cross-linking domain DUF4777 PF16007.5 GBG65740.1 - 1 9.7 3.3 2 8.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) RT_RNaseH_2 PF17919.1 GBG65742.1 - 4.1e-31 107.0 0.0 1.7e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65742.1 - 2.6e-30 105.6 0.0 4.3e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65742.1 - 4e-21 75.3 0.0 1.1e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65742.1 - 7.2e-15 54.8 2.5 1e-14 54.3 0.0 2.6 4 0 0 4 4 4 1 Integrase zinc binding domain Chromo PF00385.24 GBG65742.1 - 5.4e-11 42.2 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG65742.1 - 5.8e-11 42.6 0.0 1.7e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65742.1 - 0.00037 20.6 0.0 0.00095 19.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG65745.1 - 3.5e-06 26.8 2.9 5.9e-06 26.1 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG65745.1 - 0.091 12.5 1.1 0.19 11.5 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle BAH PF01426.18 GBG65748.1 - 1.6e-17 63.5 0.1 7.4e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 BAH domain TFIIS_M PF07500.14 GBG65748.1 - 4e-10 40.1 0.2 1.7e-09 38.1 0.1 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PTPRCAP PF15713.5 GBG65750.1 - 0.0081 16.5 0.2 0.0081 16.5 0.2 2.4 3 0 0 3 3 3 1 Protein tyrosine phosphatase receptor type C-associated Sporozoite_P67 PF05642.11 GBG65750.1 - 0.024 12.8 1.0 0.038 12.1 1.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PGA2 PF07543.12 GBG65750.1 - 8.5 6.3 11.4 9.8 6.2 6.2 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 Integrase_H2C2 PF17921.1 GBG65752.1 - 6.7e-12 45.3 0.0 1.9e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65752.1 - 8.5e-11 42.1 0.0 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG65752.1 - 3.7e-05 24.2 0.0 9.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65752.1 - 0.0024 18.5 0.0 0.0062 17.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG65752.1 - 0.0075 16.6 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG65752.1 - 0.0098 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DBD_Tnp_Hermes PF10683.9 GBG65754.1 - 0.064 13.0 0.1 0.39 10.4 0.0 2.2 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain AdoMet_MTase PF07757.13 GBG65754.1 - 0.14 12.5 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase SM-ATX PF14438.6 GBG65756.1 - 3.8e-26 91.1 0.3 7.2e-26 90.1 0.3 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 GBG65756.1 - 5.6e-25 87.7 0.3 1.1e-24 86.8 0.3 1.5 1 0 0 1 1 1 1 LsmAD domain PAM2 PF07145.15 GBG65756.1 - 3.3e-08 32.7 4.6 0.0012 18.4 0.4 3.3 1 1 1 2 2 2 2 Ataxin-2 C-terminal region Tudor_2 PF18104.1 GBG65756.1 - 0.037 13.7 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain LSM14 PF12701.7 GBG65756.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain SM-ATX PF14438.6 GBG65757.1 - 3.8e-26 91.1 0.3 7.2e-26 90.1 0.3 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 GBG65757.1 - 5.5e-25 87.7 0.3 1.1e-24 86.8 0.3 1.5 1 0 0 1 1 1 1 LsmAD domain PAM2 PF07145.15 GBG65757.1 - 3.3e-08 32.7 4.6 0.0012 18.4 0.4 3.3 1 1 1 2 2 2 2 Ataxin-2 C-terminal region Tudor_2 PF18104.1 GBG65757.1 - 0.037 13.7 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain LSM14 PF12701.7 GBG65757.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain RT_RNaseH_2 PF17919.1 GBG65760.1 - 5.6e-22 77.7 0.0 1.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LRR_4 PF12799.7 GBG65760.1 - 2.4e-19 69.1 4.5 1.7e-07 31.4 0.4 5.1 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) IQ PF00612.27 GBG65760.1 - 4.3e-15 54.0 40.3 1.1e-06 27.8 0.7 6.4 6 0 0 6 6 6 4 IQ calmodulin-binding motif LRR_8 PF13855.6 GBG65760.1 - 5.8e-11 42.0 12.3 4.8e-07 29.4 7.8 4.0 3 0 0 3 3 3 2 Leucine rich repeat RT_RNaseH PF17917.1 GBG65760.1 - 1.7e-10 41.1 0.0 5.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LRR_9 PF14580.6 GBG65760.1 - 8.7e-09 35.1 0.3 0.00082 18.9 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 GBG65760.1 - 0.038 14.0 10.6 2.2 8.6 0.5 5.5 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 GBG65760.1 - 0.15 12.7 11.9 17 6.4 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat NICE-1 PF15845.5 GBG65760.1 - 0.16 12.7 10.3 1.2 9.9 10.3 2.6 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family RT_RNaseH_2 PF17919.1 GBG65761.1 - 1.8e-29 101.7 0.0 1.5e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65761.1 - 6.8e-29 100.3 0.0 1.3e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65761.1 - 1.5e-20 73.7 0.7 1e-16 61.1 0.2 2.6 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65761.1 - 1.1e-14 54.3 0.1 2.3e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65761.1 - 1.7e-12 47.6 0.0 5e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65761.1 - 2.7e-05 24.3 0.0 5.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger GNT-I PF03071.15 GBG65761.1 - 0.031 13.1 0.1 0.058 12.2 0.1 1.3 1 0 0 1 1 1 0 GNT-I family PilN PF05137.13 GBG65761.1 - 0.18 12.0 0.0 2.7 8.2 0.0 2.3 1 1 1 2 2 2 0 Fimbrial assembly protein (PilN) gag-asp_proteas PF13975.6 GBG65762.1 - 5.3e-08 33.3 0.0 9.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65762.1 - 9.7e-06 26.1 0.0 1.7e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65762.1 - 0.00062 19.5 0.1 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG65762.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease VIR_N PF15912.5 GBG65762.1 - 0.53 9.8 5.2 0.78 9.3 5.2 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PTPRCAP PF15713.5 GBG65762.1 - 2.3 8.5 9.0 0.54 10.5 5.7 1.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF3381 PF11861.8 GBG65762.1 - 4.1 7.2 11.2 7.7 6.3 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Lactamase_B PF00753.27 GBG65763.1 - 2.3e-08 34.3 2.5 0.00097 19.2 1.3 3.0 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Siva PF05458.12 GBG65764.1 - 5.3e-09 36.0 18.2 5.3e-09 36.0 18.2 2.4 3 0 0 3 3 3 1 Cd27 binding protein (Siva) Ssu72 PF04722.13 GBG65765.1 - 6.7e-75 250.9 0.1 8.9e-75 250.5 0.1 1.1 1 0 0 1 1 1 1 Ssu72-like protein NYN_YacP PF05991.11 GBG65765.1 - 0.036 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 YacP-like NYN domain Defensin_1 PF00323.19 GBG65765.1 - 2 9.0 10.5 15 6.3 3.0 3.4 2 1 1 3 3 3 0 Mammalian defensin Gamma-thionin PF00304.20 GBG65765.1 - 5.8 7.3 9.8 0.7 10.2 3.9 2.4 3 0 0 3 3 3 0 Gamma-thionin family RVT_1 PF00078.27 GBG65767.1 - 2.8e-28 98.9 0.0 6.1e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG65767.1 - 8.2e-09 35.9 0.3 3.5e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65767.1 - 1.7e-07 31.8 0.0 6.3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease rve PF00665.26 GBG65767.1 - 3.5e-07 30.4 0.0 1.6e-06 28.3 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG65767.1 - 6.1e-07 29.3 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG65767.1 - 8.1e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG65767.1 - 0.035 14.4 0.4 0.18 12.1 0.4 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein NPV_P10 PF05531.12 GBG65767.1 - 0.33 11.4 3.7 11 6.5 3.7 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2927 PF11150.8 GBG65767.1 - 0.56 10.3 6.8 1.3 9.0 6.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) Fzo_mitofusin PF04799.13 GBG65767.1 - 2.7 7.5 10.2 2.5 7.6 6.5 2.7 3 0 0 3 3 3 0 fzo-like conserved region Integrase_H2C2 PF17921.1 GBG65768.1 - 2.1e-15 56.6 0.4 6.9e-15 54.9 0.4 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG65768.1 - 6e-12 45.8 0.2 2.3e-11 43.9 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65768.1 - 2.3e-09 37.5 0.0 7.1e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG65768.1 - 5.5e-05 23.1 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG65768.1 - 0.00032 20.6 0.1 0.00092 19.1 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG65768.1 - 0.014 15.6 2.6 0.028 14.6 0.1 2.7 3 0 0 3 3 3 0 H2C2 zinc finger DUF4187 PF13821.6 GBG65768.1 - 0.02 14.6 0.9 0.081 12.7 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RVT_1 PF00078.27 GBG65769.1 - 7.6e-28 97.5 0.0 1.1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65769.1 - 6.3e-23 80.7 0.0 1.4e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65769.1 - 7.8e-15 55.1 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG65769.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG65770.1 - 9.2e-26 90.7 0.0 1.6e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65770.1 - 7.5e-20 70.8 0.6 1.9e-19 69.5 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65770.1 - 2.8e-11 43.7 0.1 1.7e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG65770.1 - 2.6e-07 31.2 0.0 9.5e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65770.1 - 8.5e-07 29.5 0.0 2.7e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG65770.1 - 2.6e-05 24.4 8.1 0.012 15.9 0.1 4.7 4 0 0 4 4 4 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG65770.1 - 2.9e-05 23.9 0.0 9.2e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG65770.1 - 8.1e-05 22.4 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG65770.1 - 0.081 13.2 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger FlxA PF14282.6 GBG65770.1 - 0.14 12.1 6.5 0.32 11.0 0.1 3.2 2 0 0 2 2 2 0 FlxA-like protein RT_RNaseH_2 PF17919.1 GBG65771.1 - 1.2e-29 102.3 0.0 2.2e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65771.1 - 2.6e-24 85.5 0.0 5.1e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65771.1 - 1e-16 61.2 0.0 3e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG65771.1 - 5.2e-11 42.5 0.2 9.8e-11 41.6 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65771.1 - 5.9e-10 39.1 0.1 1.5e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG65772.1 - 1.1e-31 108.8 0.0 2.4e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65772.1 - 3.5e-29 101.2 0.1 7.1e-29 100.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65772.1 - 5.2e-18 64.9 0.2 9.8e-18 64.0 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65772.1 - 5.6e-12 45.9 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65772.1 - 2.2e-05 24.6 0.0 6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG65772.1 - 0.0013 18.4 0.2 0.0065 16.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) DHC_N2 PF08393.13 GBG65773.1 - 2.4e-117 392.4 0.3 4.5e-117 391.5 0.0 1.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 RVT_1 PF00078.27 GBG65773.1 - 1.6e-29 103.0 0.1 3.1e-29 102.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65773.1 - 7.3e-29 99.7 0.0 1.6e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65773.1 - 1.4e-23 83.2 0.0 4.7e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase CENP-B_dimeris PF09026.10 GBG65773.1 - 3 8.3 10.3 8.2 6.9 10.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Integrase_H2C2 PF17921.1 GBG65775.1 - 3.8e-18 65.3 0.1 7.6e-18 64.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65775.1 - 7.1e-16 58.5 0.0 1.6e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65775.1 - 0.03 14.5 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger FtsK_4TM PF13491.6 GBG65775.1 - 0.049 13.3 0.2 0.076 12.7 0.2 1.3 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE Calpain_inhib PF00748.19 GBG65775.1 - 2.2 8.8 3.9 4.8 7.7 3.9 1.6 1 0 0 1 1 1 0 Calpain inhibitor RT_RNaseH_2 PF17919.1 GBG65776.1 - 8.3e-30 102.8 0.0 2.9e-29 101.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65776.1 - 1.3e-29 102.5 0.0 4.4e-29 100.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65776.1 - 1e-11 44.8 0.0 2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rhamno_transf PF11316.8 GBG65776.1 - 0.054 12.9 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 Putative rhamnosyl transferase zf-CCHC PF00098.23 GBG65777.1 - 0.00034 20.5 2.8 0.00089 19.2 2.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG65777.1 - 0.038 13.8 1.4 0.074 12.9 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG65777.1 - 0.096 12.7 1.0 0.4 10.7 1.0 2.0 1 0 0 1 1 1 0 Zinc knuckle APG6_N PF17675.1 GBG65777.1 - 0.58 10.7 23.0 0.12 12.9 2.3 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Usp PF00582.26 GBG65779.1 - 2.5e-17 63.7 0.5 2.5e-17 63.7 0.5 3.9 4 0 0 4 4 4 1 Universal stress protein family DUF2052 PF09747.9 GBG65779.1 - 0.0051 17.0 17.5 0.0051 17.0 17.5 3.3 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) CAF1 PF04857.20 GBG65779.1 - 1.2 8.3 5.6 10 5.2 0.0 2.5 2 0 0 2 2 2 0 CAF1 family ribonuclease Presenilin PF01080.17 GBG65779.1 - 4.8 5.8 22.3 0.99 8.1 4.0 2.6 2 0 0 2 2 2 0 Presenilin DUF2828 PF11443.8 GBG65779.1 - 5.6 4.9 12.3 2.8 5.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) RT_RNaseH_2 PF17919.1 GBG65781.1 - 1.7e-19 69.7 0.0 3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65781.1 - 2.4e-09 37.4 0.0 4.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65781.1 - 9.5e-09 35.1 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG65781.1 - 0.044 14.4 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG65781.1 - 0.095 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG65783.1 - 5.4e-21 74.5 0.0 8e-15 54.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65783.1 - 8.2e-16 57.9 0.2 2.2e-15 56.5 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65783.1 - 4.2e-15 55.9 0.2 7.3e-15 55.1 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG65783.1 - 5.8e-11 42.6 0.0 2e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG65783.1 - 1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG65783.1 - 2.3e-09 37.5 0.0 5.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG65783.1 - 0.00014 22.0 0.1 0.00027 21.1 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG65784.1 - 0.00076 19.7 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG65784.1 - 0.00086 19.8 0.1 0.0018 18.8 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65784.1 - 0.0014 19.2 0.0 0.0029 18.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65784.1 - 0.0032 17.2 0.2 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG65784.1 - 0.0046 17.0 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG65784.1 - 0.0093 16.3 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Ku_N PF03731.15 GBG65784.1 - 0.073 12.8 0.1 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain AAA_6 PF12774.7 GBG65785.1 - 1e-75 254.8 0.0 1.7e-58 198.2 0.0 2.2 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region CENP-Q PF13094.6 GBG65785.1 - 0.06 13.5 3.0 0.11 12.7 3.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3323 PF11796.8 GBG65785.1 - 0.069 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) HisKA_2 PF07568.12 GBG65785.1 - 0.14 12.3 0.4 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase Cyclin_C_2 PF16899.5 GBG65788.1 - 0.021 15.2 2.3 0.95 9.9 0.1 2.5 2 0 0 2 2 2 0 Cyclin C-terminal domain CENP-Q PF13094.6 GBG65789.1 - 0.012 15.8 4.5 0.012 15.8 4.5 2.7 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2408 PF10303.9 GBG65789.1 - 0.48 11.0 5.0 5.2 7.6 1.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) CRISPR_assoc PF08798.11 GBG65790.1 - 1.2 9.2 5.8 4.5 7.3 5.8 2.0 1 1 0 1 1 1 0 CRISPR associated protein Presenilin PF01080.17 GBG65790.1 - 9.4 4.9 6.9 13 4.4 6.9 1.3 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG65791.1 - 9.8e-23 80.1 0.0 1.7e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65791.1 - 3.6e-21 75.4 0.0 6.3e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65791.1 - 7.7e-14 51.7 0.3 1.8e-08 34.2 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG65791.1 - 1e-05 26.1 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65791.1 - 1.9e-05 25.1 0.0 4.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG65791.1 - 0.0006 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65791.1 - 0.0028 17.4 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG65792.1 - 0.017 15.7 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4335 PF14233.6 GBG65792.1 - 0.037 14.0 0.1 8.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) Asp_protease_2 PF13650.6 GBG65792.1 - 0.16 12.6 0.0 0.38 11.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Actin PF00022.19 GBG65793.1 - 1.5e-148 494.8 0.0 6.3e-148 492.7 0.0 1.7 1 1 0 1 1 1 1 Actin zf-CCHC PF00098.23 GBG65794.1 - 2.8e-05 24.0 1.5 2.8e-05 24.0 1.5 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG65794.1 - 0.016 14.9 0.5 0.032 14.0 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG65794.1 - 0.018 14.9 0.5 0.058 13.2 0.5 1.9 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG65795.1 - 2.5e-10 40.4 0.0 5.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65795.1 - 3.4e-06 26.8 0.4 7.7e-06 25.6 0.4 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVP_2 PF08284.11 GBG65796.1 - 1.1e-05 25.3 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65796.1 - 2e-05 25.2 0.7 0.26 11.9 0.1 2.6 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.10 GBG65796.1 - 2.4e-05 24.1 0.5 0.17 11.7 0.1 2.3 2 0 0 2 2 2 2 Aspartyl protease cNMP_binding PF00027.29 GBG65796.1 - 0.00057 19.9 0.1 2.5 8.2 0.0 3.4 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain TetR_C_9 PF14514.6 GBG65796.1 - 0.014 15.5 0.0 8.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RT_RNaseH_2 PF17919.1 GBG65797.1 - 1.6e-28 98.7 0.0 4.2e-28 97.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65797.1 - 2e-28 98.7 0.2 9.1e-28 96.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG65797.1 - 0.00084 19.2 0.0 0.0024 17.7 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG65797.1 - 0.046 14.0 0.1 0.046 14.0 0.1 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG65797.1 - 0.06 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG65798.1 - 1.4e-26 93.4 0.1 4.2e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65798.1 - 6.4e-22 77.5 0.0 1.6e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65798.1 - 6.4e-19 68.2 0.0 2.4e-18 66.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG65798.1 - 3.2e-13 49.8 0.0 5.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Chromo PF00385.24 GBG65798.1 - 0.0021 17.9 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG65799.1 - 1.1e-34 119.9 0.1 1.8e-34 119.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65799.1 - 4e-29 101.0 0.0 2e-28 98.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65799.1 - 5.9e-29 100.1 0.0 3.3e-28 97.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase MoCF_biosynth PF00994.24 GBG65799.1 - 0.0017 18.1 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain Topo_Zn_Ribbon PF08272.11 GBG65800.1 - 0.071 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RT_RNaseH_2 PF17919.1 GBG65801.1 - 1.6e-29 101.9 0.0 3.6e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65801.1 - 1.7e-25 89.3 0.0 3.5e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65801.1 - 1.6e-23 83.4 0.3 3.7e-23 82.2 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65801.1 - 1.6e-14 53.8 0.2 4.1e-14 52.4 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG65801.1 - 0.00045 20.4 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG65801.1 - 0.0021 17.7 3.6 0.35 10.5 0.0 2.3 2 0 0 2 2 2 2 Phage capsid scaffolding protein (GPO) serine peptidase CENP-H PF05837.12 GBG65801.1 - 0.025 15.0 0.4 0.2 12.1 0.1 2.6 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Mu-like_Pro PF10123.9 GBG65801.1 - 0.068 12.7 3.8 0.12 12.0 3.8 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein AcylCoA_dehyd_C PF12186.8 GBG65801.1 - 0.15 12.2 0.8 0.59 10.3 0.3 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal YabA PF06156.13 GBG65801.1 - 0.25 12.0 3.7 0.25 12.0 0.0 2.9 4 0 0 4 4 4 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 GBG65801.1 - 2.4 8.3 7.4 7.6 6.7 0.3 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 RVT_1 PF00078.27 GBG65802.1 - 5.4e-31 107.8 0.1 1e-30 107.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65802.1 - 5.6e-28 96.9 0.0 1.7e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65802.1 - 6.7e-28 97.1 0.1 3.2e-27 94.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase MoCF_biosynth PF00994.24 GBG65803.1 - 1e-22 80.4 0.4 1.9e-22 79.5 0.4 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 GBG65803.1 - 7.4e-17 61.3 0.1 2.3e-16 59.7 0.1 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) RVT_1 PF00078.27 GBG65803.1 - 4e-14 52.7 0.1 8.2e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG65803.1 - 0.0043 17.0 0.6 0.014 15.4 0.6 1.8 1 0 0 1 1 1 1 Zinc knuckle Macoilin PF09726.9 GBG65803.1 - 4.5 5.7 10.9 8 4.9 10.9 1.3 1 0 0 1 1 1 0 Macoilin family zf-CCHC_2 PF13696.6 GBG65804.1 - 0.12 12.2 0.7 0.2 11.5 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG65805.1 - 1.9e-22 79.5 0.0 5.3e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65805.1 - 7.3e-21 74.1 0.0 1.4e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65805.1 - 2.1e-05 24.2 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TolA_bind_tri PF16331.5 GBG65806.1 - 0.00061 19.8 4.7 0.00061 19.8 4.7 2.7 2 1 1 3 3 3 1 TolA binding protein trimerisation DUF1664 PF07889.12 GBG65806.1 - 0.0035 17.4 1.9 0.0066 16.5 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 GBG65806.1 - 0.13 12.5 1.8 0.88 9.9 0.0 2.8 2 1 0 2 2 2 0 Retrotransposon gag protein DDRGK PF09756.9 GBG65806.1 - 0.22 11.1 9.1 0.36 10.4 9.1 1.3 1 0 0 1 1 1 0 DDRGK domain DUF2730 PF10805.8 GBG65806.1 - 0.39 10.8 2.3 1.5 9.0 2.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1825 PF08855.10 GBG65806.1 - 0.41 10.6 3.3 0.26 11.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) ATG16 PF08614.11 GBG65806.1 - 0.5 10.6 19.7 0.8 9.9 19.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 GBG65806.1 - 1.2 9.8 15.5 1.1 9.9 2.3 3.1 2 1 1 3 3 3 0 SlyX RT_RNaseH_2 PF17919.1 GBG65807.1 - 8.5e-25 86.7 0.0 2.1e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65807.1 - 2.4e-22 79.6 0.1 4.1e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65807.1 - 4.4e-21 75.1 0.0 1.1e-20 73.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG65807.1 - 0.00012 22.3 2.7 0.02 15.2 0.1 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG65807.1 - 0.0011 19.4 0.0 0.0038 17.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65807.1 - 0.0013 19.3 0.0 0.0044 17.6 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65807.1 - 0.0068 16.2 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG65807.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_4 PF14392.6 GBG65807.1 - 0.27 11.0 3.1 1.8 8.4 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG65807.1 - 2.7 8.0 8.1 13 5.9 1.3 3.6 4 0 0 4 4 4 0 Zinc knuckle RVT_1 PF00078.27 GBG65808.1 - 3.8e-36 124.7 1.2 1.6e-23 83.4 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65808.1 - 1.5e-30 105.2 0.0 4.2e-30 103.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65808.1 - 1.2e-26 93.1 0.0 3.2e-26 91.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65808.1 - 8.1e-09 35.7 0.0 1.1e-07 32.0 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG65808.1 - 6.6e-06 26.6 0.0 1.7e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG65808.1 - 1.7e-05 25.0 2.9 0.21 11.9 0.0 4.4 3 0 0 3 3 3 2 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG65808.1 - 7.6e-05 23.3 0.0 0.00028 21.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Chromo PF00385.24 GBG65808.1 - 0.0032 17.3 0.1 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG65808.1 - 0.041 13.7 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG65808.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_4 PF14392.6 GBG65809.1 - 0.022 14.5 0.9 0.041 13.6 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG65810.1 - 1.7e-06 28.2 2.3 0.0013 19.0 0.0 3.2 3 0 0 3 3 3 2 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG65811.1 - 8.2e-27 93.2 0.0 1.8e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65811.1 - 3.8e-26 92.0 0.1 6.3e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65811.1 - 4.9e-24 84.6 0.0 9.7e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65811.1 - 3e-16 59.3 0.1 9.4e-16 57.7 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65811.1 - 4.1e-10 39.9 0.0 1.3e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DUF1629 PF07791.11 GBG65812.1 - 0.064 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) API5 PF05918.11 GBG65812.1 - 8.2 5.1 5.9 22 3.7 5.9 1.6 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MoeA_N PF03453.17 GBG65813.1 - 2.8e-26 92.2 1.8 4.3e-26 91.6 1.8 1.1 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) RVT_1 PF00078.27 GBG65814.1 - 1.3e-29 103.3 0.1 2.5e-29 102.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65814.1 - 1.5e-28 98.7 0.0 4.1e-28 97.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65814.1 - 5.3e-26 91.0 0.3 1.5e-25 89.5 0.3 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65814.1 - 5.1e-08 33.1 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG65814.1 - 0.0016 18.2 1.1 0.0048 16.6 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) Integrase_H2C2 PF17921.1 GBG65814.1 - 0.014 15.5 0.8 0.044 13.9 0.8 1.9 1 0 0 1 1 1 0 Integrase zinc binding domain Integrase_Zn PF02022.19 GBG65814.1 - 0.15 12.0 0.3 14 5.7 0.6 3.1 3 0 0 3 3 3 0 Integrase Zinc binding domain RT_RNaseH_2 PF17919.1 GBG65815.1 - 9.9e-26 89.7 0.0 1.7e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65815.1 - 5.8e-23 81.2 0.0 1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65815.1 - 3.8e-11 42.9 0.2 6e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG65815.1 - 0.081 12.3 9.2 0.11 11.9 9.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG65815.1 - 0.16 10.1 8.9 0.2 9.8 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG65815.1 - 1.4 7.1 10.0 2 6.6 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG65816.1 - 2.3e-33 114.2 0.0 3.9e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65816.1 - 1.3e-25 89.7 0.0 2.5e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase tRNA_deacylase PF04414.12 GBG65816.1 - 0.098 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase RT_RNaseH_2 PF17919.1 GBG65817.1 - 1.4e-23 82.8 0.0 2.8e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65817.1 - 6.4e-21 74.6 0.0 1.5e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ACT_3 PF10000.9 GBG65817.1 - 0.092 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF659 PF04937.15 GBG65818.1 - 5.6e-10 39.3 0.0 9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65818.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.17 GBG65820.1 - 0.0012 19.1 0.4 0.0038 17.5 0.4 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG65822.1 - 1.1e-33 116.6 0.0 2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65822.1 - 4.4e-17 62.0 0.0 1.3e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG65822.1 - 1e-06 28.6 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG65822.1 - 9e-06 25.9 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG65822.1 - 0.00025 21.6 0.0 0.00047 20.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65822.1 - 0.00035 21.1 0.0 0.00073 20.0 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG65822.1 - 0.0028 17.5 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RT_RNaseH PF17917.1 GBG65824.1 - 8.7e-21 74.2 0.0 1.9e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65824.1 - 4.2e-20 71.6 0.0 8.9e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65824.1 - 5.8e-05 22.7 0.0 0.00014 21.5 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65827.1 - 1e-31 108.9 0.0 2.4e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65827.1 - 4.1e-28 97.7 0.0 9.4e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65827.1 - 2.8e-27 95.7 0.0 4.6e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65827.1 - 1.7e-14 53.6 1.2 4e-14 52.5 1.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65827.1 - 4e-09 36.7 0.0 8.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG65827.1 - 1.6e-08 34.4 0.0 6.2e-05 22.8 0.0 2.4 1 1 1 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65827.1 - 0.00019 22.0 0.0 0.16 12.7 0.0 2.4 1 1 1 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG65827.1 - 0.012 16.1 0.0 0.16 12.6 0.0 2.2 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease HEM4 PF02602.15 GBG65827.1 - 0.052 12.9 0.0 2 7.7 0.0 2.5 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD RVT_1 PF00078.27 GBG65828.1 - 2.3e-27 96.0 0.1 3.5e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65828.1 - 3.6e-17 62.2 0.0 1.6e-16 60.1 0.0 2.2 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65828.1 - 8.3e-15 55.0 0.2 1.2e-13 51.3 0.1 2.6 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65829.1 - 1.9e-33 115.9 0.0 4e-27 95.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG65829.1 - 7.3e-09 35.5 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65829.1 - 2.7e-06 27.9 0.0 6.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65829.1 - 0.00011 22.7 0.0 0.00024 21.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF5069 PF16798.5 GBG65829.1 - 0.015 15.5 0.8 0.081 13.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) Retrotrans_gag PF03732.17 GBG65829.1 - 0.024 14.9 0.0 0.25 11.6 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG65829.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease PEP-utilisers_N PF05524.13 GBG65829.1 - 0.2 11.8 4.7 0.64 10.2 4.7 1.9 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal NRDE-2 PF08424.10 GBG65829.1 - 0.3 10.2 2.5 0.54 9.3 2.5 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Asp_protease_2 PF13650.6 GBG65830.1 - 5e-14 52.7 0.0 2.8e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG65830.1 - 3.5e-13 49.5 0.0 2e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG65830.1 - 5.1e-13 49.4 0.0 8.3e-07 29.5 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG65830.1 - 1e-07 31.7 0.1 1.7e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG65830.1 - 4.4e-07 29.7 0.0 0.027 14.3 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease CCD48 PF15799.5 GBG65830.1 - 0.0031 15.9 3.2 0.0057 15.0 3.2 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 Retrotrans_gag PF03732.17 GBG65830.1 - 0.0052 17.0 3.0 0.0071 16.6 0.0 2.7 3 0 0 3 3 2 1 Retrotransposon gag protein CCDC85 PF10226.9 GBG65830.1 - 0.066 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 CCDC85 family bZIP_2 PF07716.15 GBG65830.1 - 0.08 13.0 3.1 0.23 11.6 3.1 1.8 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 GBG65830.1 - 0.3 11.2 1.8 0.74 10.0 1.8 1.6 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.18 GBG65830.1 - 0.34 11.2 4.5 0.13 12.5 1.3 2.0 2 0 0 2 2 1 0 Homeobox associated leucine zipper ZapB PF06005.12 GBG65830.1 - 2.7 8.5 6.2 3.5 8.2 3.6 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 GBG65830.1 - 7.9 6.3 7.1 0.7 9.7 2.0 1.9 2 0 0 2 2 2 0 Septum formation initiator RT_RNaseH_2 PF17919.1 GBG65832.1 - 1.7e-67 223.7 0.3 8.4e-33 112.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65832.1 - 7e-60 199.8 0.8 6.1e-29 100.4 0.2 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65832.1 - 1.1e-30 106.9 0.1 4.1e-27 95.1 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2389 PF09493.10 GBG65832.1 - 0.021 15.4 0.4 2.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Tryptophan-rich protein (DUF2389) RVT_1 PF00078.27 GBG65833.1 - 1.3e-29 103.3 0.1 2e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65833.1 - 4.7e-19 68.3 0.3 1.7e-16 60.0 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65833.1 - 7.6e-15 55.1 0.8 5.4e-08 33.1 0.7 2.7 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65834.1 - 4.5e-33 113.3 0.1 1e-32 112.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65834.1 - 6.9e-30 103.4 0.4 1.7e-29 102.2 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65834.1 - 3.4e-18 65.5 0.1 7.7e-18 64.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65834.1 - 3.3e-14 53.1 0.0 1.7e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG65834.1 - 0.028 14.6 0.0 0.093 13.0 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG65836.1 - 2.5e-28 98.0 0.0 8.8e-28 96.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65836.1 - 6.9e-24 84.1 0.1 1.8e-23 82.8 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG65836.1 - 0.017 14.8 4.3 0.097 12.3 0.0 2.5 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RE_AlwI PF09491.10 GBG65837.1 - 0.99 8.1 9.0 0.83 8.4 8.1 1.3 1 1 0 1 1 1 0 AlwI restriction endonuclease Med9 PF07544.13 GBG65837.1 - 2.7 8.2 18.2 0.39 10.8 1.0 4.0 3 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Prominin PF05478.11 GBG65837.1 - 5.1 4.9 5.7 1.8 6.4 2.7 1.6 1 1 1 2 2 2 0 Prominin Tom22 PF04281.13 GBG65838.1 - 0.015 15.1 0.3 0.028 14.2 0.3 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 GhoS PF11080.8 GBG65838.1 - 0.056 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Endoribonuclease GhoS Mu-like_Pro PF10123.9 GBG65838.1 - 0.087 12.4 5.5 0.13 11.8 5.5 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein Spectrin PF00435.21 GBG65838.1 - 0.62 10.6 5.7 0.73 10.4 1.3 2.7 2 1 1 3 3 3 0 Spectrin repeat RVT_1 PF00078.27 GBG65841.1 - 2.5e-29 102.4 0.0 5e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65841.1 - 6.7e-23 81.0 0.0 1.3e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65841.1 - 3.6e-22 78.3 0.0 7.7e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG65841.1 - 5.5e-08 32.7 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG65841.1 - 1.4e-07 31.7 0.0 4.4e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG65841.1 - 1.5e-06 28.8 0.0 2.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65841.1 - 0.00016 22.2 0.0 0.00033 21.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG65841.1 - 0.48 10.6 3.7 1.1 9.4 3.7 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain PA26 PF04636.13 GBG65842.1 - 0.15 11.0 7.1 0.21 10.5 7.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) IL11 PF07400.11 GBG65842.1 - 0.32 10.6 2.4 0.83 9.3 0.1 2.3 2 0 0 2 2 2 0 Interleukin 11 DUF4407 PF14362.6 GBG65842.1 - 0.82 9.0 7.8 33 3.7 7.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 GBG65842.1 - 1.1 9.7 8.3 49 4.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 GBG65842.1 - 1.5 9.4 4.3 0.92 10.0 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RT_RNaseH_2 PF17919.1 GBG65843.1 - 2.8e-30 104.3 0.0 5e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65843.1 - 7e-24 84.1 0.1 1.4e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65843.1 - 2.7e-20 72.2 0.3 6.5e-20 71.0 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG65843.1 - 3.1e-10 40.3 0.1 6.4e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65843.1 - 0.00016 21.8 0.0 0.00038 20.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG65845.1 - 1.2e-08 35.4 0.0 1.4e-07 32.0 0.0 2.7 3 0 0 3 3 3 1 Aspartyl protease RVP_2 PF08284.11 GBG65845.1 - 4.4e-08 33.0 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG65845.1 - 6.4e-06 26.6 0.0 3e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG65845.1 - 0.0016 18.2 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG65845.1 - 0.0019 18.5 0.0 0.0084 16.4 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein WTX PF09422.10 GBG65845.1 - 1.8 7.6 9.7 0.027 13.6 0.9 2.0 2 0 0 2 2 2 0 WTX protein IL28A PF15177.6 GBG65845.1 - 2.7 7.8 10.6 0.27 11.1 5.7 1.8 2 0 0 2 2 2 0 Interleukin-28A Coatomer_WDAD PF04053.14 GBG65846.1 - 0.0008 18.6 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region SH3-WW_linker PF16618.5 GBG65848.1 - 2.2 8.7 7.7 0.76 10.2 4.3 1.7 1 1 1 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 DUF3500 PF12006.8 GBG65848.1 - 2.7 7.4 8.8 0.7 9.3 4.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3500) RVT_1 PF00078.27 GBG65850.1 - 4.4e-06 26.4 0.0 7.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65850.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65850.1 - 0.00024 21.3 0.0 0.00052 20.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG65850.1 - 0.0058 16.6 0.6 0.015 15.4 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF4913 PF16259.5 GBG65850.1 - 0.65 10.1 2.5 0.7 10.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) SWIRM-assoc_1 PF16495.5 GBG65852.1 - 0.0016 18.4 0.5 0.004 17.1 0.5 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Dak2 PF02734.17 GBG65852.1 - 0.011 15.7 0.7 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 DAK2 domain Phage_Nu1 PF07471.12 GBG65852.1 - 6.2 6.6 7.8 1.1 9.1 1.9 2.3 2 1 0 2 2 2 0 Phage DNA packaging protein Nu1 RT_RNaseH_2 PF17919.1 GBG65854.1 - 9e-34 115.5 0.0 1.6e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65854.1 - 5.4e-29 100.6 0.1 9.7e-29 99.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2584 PF10763.9 GBG65854.1 - 0.029 14.5 0.1 0.096 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2584) DUF3863 PF12979.7 GBG65854.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) GramPos_pilinD3 PF16570.5 GBG65855.1 - 0.1 13.3 0.9 0.33 11.7 0.1 2.0 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain DUF659 PF04937.15 GBG65856.1 - 5.1e-14 52.4 0.0 8.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65856.1 - 1.4e-06 28.0 0.0 5.2e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Rx_N PF18052.1 GBG65856.1 - 3.8 7.8 5.1 43 4.5 0.2 2.9 2 0 0 2 2 2 0 Rx N-terminal domain VCBS PF13517.6 GBG65856.1 - 6.3 7.5 8.4 17 6.1 0.3 3.3 3 2 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DsrH PF04077.12 GBG65860.1 - 0.0001 22.3 8.6 43 4.3 0.1 10.3 10 4 3 13 13 13 1 DsrH like protein PUB PF09409.10 GBG65860.1 - 2.4 8.2 11.2 27 4.8 0.1 5.6 6 1 0 6 6 6 0 PUB domain Elong-fact-P_C PF09285.11 GBG65861.1 - 0.12 12.2 1.7 5.7 6.8 0.1 3.5 4 0 0 4 4 4 0 Elongation factor P, C-terminal DUF659 PF04937.15 GBG65863.1 - 4.7e-20 72.0 0.0 1e-19 70.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG65865.1 - 2.5e-08 33.7 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNF5 PF04855.12 GBG65866.1 - 2.1e-22 80.1 0.0 2.3e-15 57.0 0.1 2.0 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 Frtz PF11768.8 GBG65871.1 - 0.027 12.8 0.0 0.035 12.4 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz RT_RNaseH_2 PF17919.1 GBG65872.1 - 2.5e-34 117.3 0.0 6e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65872.1 - 7.9e-31 106.5 0.1 2e-30 105.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65872.1 - 0.025 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) BBIP10 PF14777.6 GBG65872.1 - 0.4 10.3 2.1 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 FancD2 PF14631.6 GBG65873.1 - 3.3e-32 111.0 0.9 4.5e-32 110.6 0.9 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease Retrotrans_gag PF03732.17 GBG65873.1 - 0.0017 18.6 0.1 0.0081 16.4 0.0 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein Herpes_UL25 PF01499.16 GBG65873.1 - 0.089 11.3 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family adh_short PF00106.25 GBG65874.1 - 2.1e-11 43.7 0.7 1.2e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG65874.1 - 1.4e-09 37.9 0.1 1.8e-09 37.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GBG65874.1 - 1.2e-05 24.9 0.4 3.8e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GBG65874.1 - 0.00042 20.3 0.6 0.00097 19.1 0.3 1.7 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.17 GBG65874.1 - 0.0031 18.0 0.8 0.0097 16.5 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 GBG65874.1 - 0.024 14.5 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GBG65874.1 - 0.067 12.6 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Integrase_H2C2 PF17921.1 GBG65875.1 - 3.6e-15 55.8 0.1 6.9e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Angiomotin_C PF12240.8 GBG65875.1 - 0.0029 17.2 0.3 0.0063 16.1 0.3 1.5 1 0 0 1 1 1 1 Angiomotin C terminal zf-CCHC PF00098.23 GBG65875.1 - 0.0053 16.8 1.5 0.012 15.6 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 GBG65875.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Peptidase_M50B PF13398.6 GBG65876.1 - 2.7e-32 112.0 9.0 5.6e-17 62.0 6.8 2.3 1 1 1 2 2 2 2 Peptidase M50B-like DUF3267 PF11667.8 GBG65876.1 - 0.29 11.4 8.0 1.4 9.2 3.5 2.7 3 1 0 3 3 3 0 Putative zincin peptidase RT_RNaseH_2 PF17919.1 GBG65877.1 - 2.3e-30 104.6 0.0 3.3e-15 55.9 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65877.1 - 2.6e-30 105.6 0.0 4.4e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG65877.1 - 3.3e-30 104.5 0.0 9.3e-30 103.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65879.1 - 3.6e-27 95.3 0.1 6.9e-27 94.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65879.1 - 1.4e-26 92.4 0.0 3.6e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65879.1 - 6.3e-25 87.5 0.0 1.6e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65879.1 - 8.3e-18 64.3 0.6 1.9e-17 63.1 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65879.1 - 9.4e-12 45.2 0.0 3.5e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG65879.1 - 8.1e-05 22.8 3.5 0.0015 18.8 0.1 4.0 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG65879.1 - 0.092 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG65880.1 - 3.1e-27 95.6 0.1 6e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65880.1 - 1.2e-26 92.6 0.0 3.2e-26 91.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65880.1 - 5.4e-25 87.7 0.0 1.4e-24 86.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65880.1 - 7.1e-18 64.5 0.6 1.7e-17 63.2 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65880.1 - 9e-12 45.2 0.0 3.1e-11 43.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG65880.1 - 6.1e-05 23.2 3.5 0.0013 18.9 0.1 4.1 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG65880.1 - 0.081 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger TypeIII_RM_meth PF12564.8 GBG65881.1 - 0.19 11.9 1.1 12 6.1 0.1 2.6 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit RT_RNaseH_2 PF17919.1 GBG65882.1 - 3e-53 178.0 0.0 2.7e-26 91.5 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65882.1 - 4.7e-51 171.5 0.0 1.8e-28 98.9 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65882.1 - 1.5e-32 112.9 0.3 1.7e-29 103.0 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG65882.1 - 7e-06 26.2 0.5 0.0048 17.2 0.0 3.6 2 0 0 2 2 2 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG65882.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease UPF0182 PF03699.13 GBG65883.1 - 0.011 13.9 1.9 0.018 13.2 1.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) RVT_1 PF00078.27 GBG65886.1 - 6.9e-29 100.9 0.0 1.2e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65886.1 - 4.9e-16 58.6 1.5 1.3e-15 57.2 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG65886.1 - 2.8e-10 40.4 0.0 8e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG65886.1 - 1e-08 34.9 0.0 2.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG65886.1 - 2.1e-05 24.6 0.0 6.1e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG65887.1 - 1.9e-28 98.4 0.0 3.1e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65887.1 - 1.6e-26 92.6 0.0 2.6e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65887.1 - 2.8e-09 36.8 0.2 4.3e-09 36.2 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG65887.1 - 0.032 14.1 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Nop14 PF04147.12 GBG65887.1 - 0.45 8.7 19.0 0.62 8.2 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG65887.1 - 0.5 9.7 20.6 0.7 9.3 20.6 1.1 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG65887.1 - 6.2 7.0 13.9 9.7 6.4 13.9 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Peptidase_M18 PF02127.15 GBG65888.1 - 1e-97 327.7 0.3 8.1e-47 160.0 0.0 4.1 3 1 1 4 4 4 4 Aminopeptidase I zinc metalloprotease (M18) RVT_1 PF00078.27 GBG65889.1 - 4.9e-45 153.8 0.1 1.6e-28 99.7 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG65889.1 - 3e-18 65.7 0.0 9.1e-18 64.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65889.1 - 4.9e-18 65.0 0.2 1.2e-17 63.8 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG65889.1 - 4.3e-06 26.9 0.0 1.5e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG65889.1 - 0.065 13.4 1.1 1.3 9.2 0.1 2.8 2 1 1 3 3 3 0 Integrase core domain Snapin_Pallidin PF14712.6 GBG65889.1 - 0.19 12.2 8.3 0.22 11.9 0.0 3.5 3 0 0 3 3 3 0 Snapin/Pallidin RT_RNaseH_2 PF17919.1 GBG65890.1 - 6.1e-30 103.2 0.0 2e-29 101.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 GBG65890.1 - 4.5e-28 98.4 0.0 8.8e-23 81.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG65890.1 - 1.3e-25 90.2 0.0 7.6e-21 74.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RT_RNaseH PF17917.1 GBG65890.1 - 1.4e-24 86.3 0.1 3.9e-24 85.0 0.1 1.8 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65890.1 - 5.4e-15 55.3 0.1 1.3e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Malectin_like PF12819.7 GBG65890.1 - 5.5e-14 52.1 0.0 9.3e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Malectin-like domain RVT_1 PF00078.27 GBG65890.1 - 3.6e-10 39.7 0.0 6.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 GBG65890.1 - 1.4e-08 34.4 25.0 1.4e-05 24.7 5.1 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GBG65890.1 - 4.4e-07 30.1 6.8 0.00027 21.2 3.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) rve PF00665.26 GBG65890.1 - 0.00033 20.9 0.0 0.0014 18.8 0.0 2.0 1 1 1 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG65890.1 - 0.014 15.6 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger LRR_1 PF00560.33 GBG65890.1 - 0.029 14.9 5.1 9.9 7.2 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat Kinase-like PF14531.6 GBG65890.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 GBG65890.1 - 0.12 11.7 2.5 7.5 5.8 0.8 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MHYT PF03707.16 GBG65890.1 - 6.3 7.1 5.5 0.71 10.1 0.6 2.0 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat HemY_N PF07219.13 GBG65891.1 - 0.054 13.7 1.0 0.054 13.7 1.0 2.0 1 1 1 2 2 2 0 HemY protein N-terminus DUF2116 PF09889.9 GBG65891.1 - 0.96 9.5 5.1 2.5 8.2 5.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) YbaB_DNA_bd PF02575.16 GBG65892.1 - 7.6e-19 67.7 2.0 1e-18 67.3 2.0 1.2 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Ribosomal_L36 PF00444.18 GBG65892.1 - 0.049 13.9 0.3 0.13 12.5 0.3 1.7 1 0 0 1 1 1 0 Ribosomal protein L36 Biotin_lipoyl PF00364.22 GBG65892.1 - 0.056 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme RT_RNaseH_2 PF17919.1 GBG65893.1 - 3.2e-34 116.9 0.0 6.7e-34 115.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65893.1 - 1.1e-29 102.8 0.0 2.3e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65893.1 - 2.6e-25 89.3 0.1 4.6e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65893.1 - 1.4e-17 63.5 0.3 1.4e-17 63.5 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG65893.1 - 7.6e-11 42.2 0.0 1.7e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DHHC PF01529.20 GBG65894.1 - 4.2e-37 127.3 5.5 4.2e-37 127.3 5.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase CitMHS PF03600.16 GBG65894.1 - 0.0036 16.5 5.5 0.0052 16.0 5.5 1.1 1 0 0 1 1 1 1 Citrate transporter Amastin PF07344.11 GBG65894.1 - 3.9 7.3 12.8 1.5 8.6 1.0 2.7 3 0 0 3 3 3 0 Amastin surface glycoprotein RT_RNaseH_2 PF17919.1 GBG65895.1 - 1.1e-33 115.2 0.1 2.7e-33 114.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65895.1 - 2.5e-31 108.1 0.1 5.1e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65895.1 - 8.1e-12 45.1 0.1 8.1e-12 45.1 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG65895.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CpxA_peri PF16527.5 GBG65895.1 - 0.1 13.0 0.2 3.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain zf-CCHC_3 PF13917.6 GBG65895.1 - 0.39 10.7 6.9 0.23 11.5 3.0 2.2 2 0 0 2 2 2 0 Zinc knuckle DUF659 PF04937.15 GBG65896.1 - 4.4e-40 137.0 0.0 7.9e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) NOA36 PF06524.12 GBG65898.1 - 0.0088 15.4 13.5 0.016 14.5 13.5 1.5 1 0 0 1 1 1 1 NOA36 protein DUF2457 PF10446.9 GBG65898.1 - 0.43 9.7 23.7 0.15 11.1 20.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 GBG65898.1 - 0.51 10.3 11.3 0.64 10.0 11.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 GBG65898.1 - 1.7 8.6 8.3 4 7.4 8.3 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 GBG65898.1 - 1.8 6.7 10.9 3.1 5.9 10.9 1.4 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 GBG65898.1 - 5.3 6.8 9.3 0.57 9.9 4.6 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RRN3 PF05327.11 GBG65898.1 - 5.8 5.3 10.6 9.1 4.7 10.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 GBG65898.1 - 8.6 5.7 14.0 0.59 9.5 7.4 2.0 2 0 0 2 2 2 0 SDA1 DHHC PF01529.20 GBG65899.1 - 1.1e-37 129.1 5.8 1.1e-37 129.1 5.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4013 PF13197.6 GBG65899.1 - 0.39 10.6 7.6 0.85 9.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) FGF-BP1 PF06473.12 GBG65901.1 - 0.031 14.1 6.3 0.036 13.9 6.3 1.0 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Afaf PF15339.6 GBG65901.1 - 0.1 12.3 1.9 0.11 12.2 1.9 1.1 1 0 0 1 1 1 0 Acrosome formation-associated factor Trypan_PARP PF05887.11 GBG65901.1 - 0.2 11.6 10.8 0.22 11.5 10.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Auts2 PF15336.6 GBG65901.1 - 0.32 11.1 16.0 0.39 10.8 16.0 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein G0-G1_switch_2 PF15103.6 GBG65901.1 - 0.38 11.2 8.2 0.45 11.0 8.2 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Connexin PF00029.19 GBG65901.1 - 1.5 8.6 6.9 1.5 8.6 6.9 1.1 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 GBG65901.1 - 1.6 7.4 4.8 1.5 7.5 4.8 1.0 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 GBG65901.1 - 1.9 8.5 7.7 1.8 8.6 7.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.14 GBG65901.1 - 2.2 6.5 9.4 2.1 6.5 9.4 1.0 1 0 0 1 1 1 0 CDC45-like protein EIIBC-GUT_N PF03612.14 GBG65901.1 - 2.3 7.9 4.8 2.2 8.0 4.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus BTB PF00651.31 GBG65902.1 - 9.2e-16 58.1 0.8 1.7e-15 57.2 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 GBG65902.1 - 8.4e-13 48.3 1.2 2.5e-12 46.8 0.2 2.2 1 1 1 2 2 2 1 BTB And C-terminal Kelch Suv3_C_1 PF18147.1 GBG65902.1 - 6.7e-05 22.7 0.0 0.00058 19.7 0.0 2.2 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 TAP42 PF04177.12 GBG65903.1 - 1.2e-67 228.3 0.1 1.5e-67 228.0 0.1 1.1 1 0 0 1 1 1 1 TAP42-like family RT_RNaseH_2 PF17919.1 GBG65905.1 - 4.9e-25 87.5 0.0 1.8e-24 85.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65905.1 - 5.7e-25 87.6 0.0 1.4e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG65905.1 - 1.3e-19 70.1 0.2 2.5e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG65905.1 - 9.2e-09 35.5 0.1 5.3e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG65905.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger TAF4 PF05236.14 GBG65905.1 - 0.068 12.9 8.5 0.12 12.1 8.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SNF2_N PF00176.23 GBG65906.1 - 1.7e-88 296.7 0.0 2.5e-88 296.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CW PF07496.15 GBG65906.1 - 1.5e-12 47.3 9.8 1.5e-12 47.3 9.8 2.9 2 0 0 2 2 2 1 CW-type Zinc Finger F-box-like PF12937.7 GBG65906.1 - 4.5e-07 29.7 0.2 1.6e-06 27.9 0.2 2.0 1 0 0 1 1 1 1 F-box-like Helicase_C PF00271.31 GBG65906.1 - 5.2e-06 26.8 0.0 2.5e-05 24.6 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 GBG65906.1 - 0.02 14.8 6.9 0.1 12.6 6.9 2.3 1 0 0 1 1 1 0 zinc-RING finger domain F-box PF00646.33 GBG65906.1 - 0.027 14.4 0.1 0.027 14.4 0.1 2.7 3 0 0 3 3 3 0 F-box domain zf-RING_UBOX PF13445.6 GBG65906.1 - 0.053 13.6 6.6 0.19 11.8 6.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DEAD PF00270.29 GBG65906.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 GBG65906.1 - 0.67 9.9 11.6 0.078 12.9 6.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG65906.1 - 1 9.6 6.9 3.1 8.0 6.9 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GBG65906.1 - 2.3 8.1 12.3 0.29 11.0 7.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF659 PF04937.15 GBG65907.1 - 2.8e-14 53.2 0.1 6.1e-14 52.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG65907.1 - 0.00071 19.3 0.1 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Cullin PF00888.22 GBG65908.1 - 8.8e-214 711.7 8.9 1e-213 711.4 8.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GBG65908.1 - 3e-08 33.6 0.6 1e-07 31.9 0.3 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain SecA_SW PF07516.13 GBG65908.1 - 0.024 14.7 0.0 0.024 14.7 0.0 3.1 2 1 0 3 3 3 0 SecA Wing and Scaffold domain SF3a60_bindingd PF12108.8 GBG65908.1 - 0.13 12.2 1.4 7.4 6.6 0.0 3.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain FRB_dom PF08771.11 GBG65908.1 - 0.24 11.8 3.1 1.2 9.6 0.5 3.2 2 1 1 3 3 3 0 FKBP12-rapamycin binding domain AIG1 PF04548.16 GBG65909.1 - 2.6e-31 108.6 0.0 4.2e-31 107.9 0.0 1.4 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GBG65909.1 - 1.2e-11 44.6 0.0 2.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG65909.1 - 4.9e-07 29.8 0.0 9.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 GBG65909.1 - 1.8e-05 24.3 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GBG65909.1 - 3.1e-05 24.1 0.7 0.028 14.5 0.4 2.3 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 GBG65909.1 - 6.1e-05 22.4 0.0 0.00016 21.1 0.0 1.7 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 GBG65909.1 - 0.001 19.5 0.7 0.0046 17.4 0.7 2.1 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 GBG65909.1 - 0.061 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Gtr1_RagA PF04670.12 GBG65909.1 - 0.071 12.5 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.26 GBG65909.1 - 0.074 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain CAP_N PF01213.19 GBG65910.1 - 0.67 9.4 17.5 2.6 7.4 2.7 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Nop14 PF04147.12 GBG65910.1 - 5.4 5.1 15.1 8 4.5 15.1 1.2 1 0 0 1 1 1 0 Nop14-like family PRIMA1 PF16101.5 GBG65910.1 - 5.5 7.1 29.6 0.35 10.9 9.4 2.7 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Aminotran_1_2 PF00155.21 GBG65911.1 - 1.1e-58 199.2 0.0 1.2e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GBG65911.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GBG65911.1 - 0.0029 16.9 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GBG65911.1 - 0.036 13.0 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V NOA36 PF06524.12 GBG65912.1 - 1.4 8.2 7.5 1.8 7.8 7.5 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG65912.1 - 2.2 6.3 5.0 2.6 6.1 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF775 PF05603.12 GBG65914.1 - 1.5e-22 80.1 0.0 1.4e-20 73.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF775) DUF775 PF05603.12 GBG65915.1 - 1.5e-27 96.5 0.0 4.4e-16 59.0 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF775) TAD2 PF18521.1 GBG65915.1 - 0.012 15.6 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 Transactivation domain 2 Hep_59 PF07052.11 GBG65916.1 - 0.00074 20.2 10.1 0.0021 18.8 10.1 1.7 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 RVT_1 PF00078.27 GBG65916.1 - 0.0032 17.0 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Bul1_N PF04425.12 GBG65916.1 - 0.094 11.5 0.6 0.13 11.0 0.6 1.1 1 0 0 1 1 1 0 Bul1 N terminus DDRGK PF09756.9 GBG65916.1 - 0.38 10.3 18.6 0.69 9.5 18.6 1.4 1 0 0 1 1 1 0 DDRGK domain DUF2514 PF10721.9 GBG65916.1 - 2.7 8.0 14.5 5.2 7.1 14.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF2058 PF09831.9 GBG65916.1 - 6.2 6.9 19.4 12 6.0 19.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF1943 PF09172.11 GBG65916.1 - 7.5 5.7 6.1 11 5.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) ATP11 PF06644.11 GBG65917.1 - 2.5e-18 66.8 23.8 1.4e-10 41.4 23.3 3.1 2 1 0 2 2 2 2 ATP11 protein LMBR1 PF04791.16 GBG65917.1 - 8.5e-05 21.6 2.2 0.00012 21.1 2.2 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Protocadherin PF08374.11 GBG65917.1 - 0.17 11.8 2.8 0.32 11.0 2.8 1.4 1 0 0 1 1 1 0 Protocadherin BUD22 PF09073.10 GBG65917.1 - 0.25 10.6 21.0 0.39 10.0 21.0 1.2 1 0 0 1 1 1 0 BUD22 Myc_N PF01056.18 GBG65917.1 - 0.43 10.4 10.0 0.8 9.5 10.0 1.4 1 0 0 1 1 1 0 Myc amino-terminal region O-antigen_lig PF13425.6 GBG65917.1 - 0.54 9.0 3.7 0.88 8.3 3.7 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1151 PF06625.11 GBG65917.1 - 1.3 9.0 32.2 1.6 8.7 20.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Pex24p PF06398.11 GBG65917.1 - 2.2 7.2 5.9 3.6 6.5 5.9 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Zip PF02535.22 GBG65917.1 - 4.4 6.4 4.6 6.1 6.0 4.6 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DUF563 PF04577.14 GBG65918.1 - 1.1e-13 51.8 0.1 2.1e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PRIMA1 PF16101.5 GBG65918.1 - 2.8 8.0 9.9 1.8 8.6 7.1 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG65918.1 - 4.8 6.6 11.3 1 8.8 7.1 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF3791 PF12668.7 GBG65919.1 - 0.23 11.5 0.0 0.4 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) DUF659 PF04937.15 GBG65920.1 - 5.3e-16 58.8 0.0 9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3791 PF12668.7 GBG65920.1 - 0.072 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Filament PF00038.21 GBG65921.1 - 6.5e-05 22.7 12.0 9.8e-05 22.1 12.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein TMF_DNA_bd PF12329.8 GBG65921.1 - 9.6e-05 22.3 7.8 9.6e-05 22.3 7.8 2.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 GBG65921.1 - 0.00079 19.5 5.5 0.0016 18.6 5.5 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 GBG65921.1 - 0.0046 17.2 14.6 0.013 15.7 14.6 1.9 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 GBG65921.1 - 0.017 15.0 7.8 0.031 14.1 7.8 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF812 PF05667.11 GBG65921.1 - 0.026 13.5 14.7 0.034 13.1 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HAUS-augmin3 PF14932.6 GBG65921.1 - 0.032 13.8 12.6 0.017 14.8 9.9 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 COG2 PF06148.11 GBG65921.1 - 0.035 14.2 6.6 0.052 13.6 5.5 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.6 GBG65921.1 - 0.046 12.4 4.7 0.062 11.9 4.7 1.2 1 0 0 1 1 1 0 AAA domain CCDC144C PF14915.6 GBG65921.1 - 0.076 12.1 16.4 0.18 10.9 15.5 1.9 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Baculo_PEP_C PF04513.12 GBG65921.1 - 0.14 12.2 0.4 0.3 11.1 0.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Macoilin PF09726.9 GBG65921.1 - 0.15 10.6 7.5 0.19 10.3 7.5 1.2 1 0 0 1 1 1 0 Macoilin family JIP_LZII PF16471.5 GBG65921.1 - 0.18 12.0 11.8 0.076 13.2 3.8 3.4 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II GAS PF13851.6 GBG65921.1 - 0.18 11.1 19.7 0.034 13.5 5.6 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 GBG65921.1 - 0.2 11.0 4.3 0.29 10.5 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 GBG65921.1 - 0.21 11.9 8.5 1.8 8.9 7.2 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup88 PF10168.9 GBG65921.1 - 0.3 8.8 7.3 0.51 8.1 7.3 1.4 1 0 0 1 1 1 0 Nuclear pore component DUF1664 PF07889.12 GBG65921.1 - 0.31 11.1 9.4 0.098 12.7 2.5 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 GBG65921.1 - 0.34 10.9 6.1 0.65 10.0 6.1 1.4 1 0 0 1 1 1 0 Laminin Domain II Nup54 PF13874.6 GBG65921.1 - 0.55 10.3 9.3 0.59 10.2 5.5 2.6 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Prominin PF05478.11 GBG65921.1 - 0.56 8.1 6.2 1.8 6.5 6.2 1.7 1 1 0 1 1 1 0 Prominin KASH_CCD PF14662.6 GBG65921.1 - 0.59 9.9 17.8 0.32 10.8 15.3 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Nas2_N PF18265.1 GBG65921.1 - 0.81 9.6 6.1 7.6 6.5 0.3 2.9 2 1 1 3 3 2 0 Nas2 N_terminal domain Gp-FAR-1 PF05823.12 GBG65921.1 - 1 9.7 7.2 2.8 8.3 5.6 2.3 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Cep57_MT_bd PF06657.13 GBG65921.1 - 1.2 9.7 9.1 2.5 8.6 6.6 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Atg14 PF10186.9 GBG65921.1 - 1.5 7.9 5.7 2.1 7.4 5.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 GBG65921.1 - 1.5 8.2 14.6 2.2 7.7 14.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 OmpH PF03938.14 GBG65921.1 - 1.7 9.0 12.7 5.9 7.2 12.7 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Jnk-SapK_ap_N PF09744.9 GBG65921.1 - 2.1 8.6 19.2 0.68 10.1 15.8 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ALMT PF11744.8 GBG65921.1 - 2.1 7.1 5.8 1.9 7.2 3.0 1.8 1 1 1 2 2 2 0 Aluminium activated malate transporter FlxA PF14282.6 GBG65921.1 - 2.2 8.3 11.5 0.11 12.5 5.7 1.9 2 0 0 2 2 1 0 FlxA-like protein Tup_N PF08581.10 GBG65921.1 - 2.5 8.5 9.2 0.71 10.2 4.4 2.4 1 1 1 2 2 2 0 Tup N-terminal ZapB PF06005.12 GBG65921.1 - 2.8 8.5 20.8 7.8 7.0 16.5 3.3 1 1 2 3 3 3 0 Cell division protein ZapB Spc7 PF08317.11 GBG65921.1 - 2.9 6.7 18.3 0.9 8.4 15.1 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 GBG65921.1 - 4.6 7.5 13.9 2.8 8.2 11.4 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 GBG65921.1 - 4.7 7.3 15.3 19 5.3 15.3 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 GBG65921.1 - 4.9 7.2 25.6 3.2 7.8 20.2 2.8 2 1 2 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 GBG65921.1 - 4.9 7.0 8.0 29 4.5 7.7 2.3 1 1 0 1 1 1 0 Septum formation initiator UPF0242 PF06785.11 GBG65921.1 - 6.2 6.9 15.8 8.9 6.4 15.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UPF0449 PF15136.6 GBG65921.1 - 6.5 7.3 9.4 1.6e+02 2.8 0.0 3.2 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 DUF5401 PF17380.2 GBG65921.1 - 6.6 4.7 18.9 8.2 4.4 18.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) FlaC_arch PF05377.11 GBG65921.1 - 8.9 6.8 8.6 8.3 6.9 3.1 3.2 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DHR10 PF18595.1 GBG65921.1 - 9 6.4 22.1 28 4.8 17.2 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF659 PF04937.15 GBG65923.1 - 1.2e-05 25.2 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG65925.1 - 7.5e-07 29.6 0.1 2.4e-06 28.0 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65925.1 - 4e-05 24.2 0.1 0.00012 22.6 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65925.1 - 0.00049 19.9 0.1 0.00092 19.0 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG65925.1 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease ATE_N PF04376.13 GBG65925.1 - 0.094 13.1 0.3 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus Topo_Zn_Ribbon PF08272.11 GBG65925.1 - 0.23 11.1 1.6 0.36 10.5 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Nucleotid_trans PF03407.16 GBG65926.1 - 2.7e-19 70.0 0.0 4.7e-18 65.9 0.0 2.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Pkinase PF00069.25 GBG65927.1 - 5.3e-54 183.3 0.0 7.3e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG65927.1 - 1e-19 70.9 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG65927.1 - 0.00091 19.2 0.0 0.006 16.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GBG65927.1 - 0.0073 15.7 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GBG65927.1 - 0.013 15.0 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Membralin PF09746.9 GBG65929.1 - 1.5e-24 86.8 23.2 7.1e-17 61.5 16.0 3.8 3 1 0 3 3 3 3 Tumour-associated protein TFIIA PF03153.13 GBG65929.1 - 0.0014 18.7 20.0 0.0014 18.7 20.0 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Methyltransf_32 PF13679.6 GBG65929.1 - 0.11 12.5 2.4 0.26 11.3 2.4 1.6 1 0 0 1 1 1 0 Methyltransferase domain FHIPEP PF00771.20 GBG65929.1 - 0.2 10.1 0.4 0.32 9.4 0.4 1.2 1 0 0 1 1 1 0 FHIPEP family Spt20 PF12090.8 GBG65929.1 - 2.6 7.6 27.8 5.8 6.4 27.8 1.5 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 GBG65929.1 - 5 7.1 7.1 12 5.9 7.1 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4746 PF15928.5 GBG65929.1 - 5.4 6.4 6.5 8.6 5.7 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Membralin PF09746.9 GBG65930.1 - 8.9e-25 87.5 22.5 7.2e-17 61.5 16.0 3.8 3 1 0 3 3 3 3 Tumour-associated protein TFIIA PF03153.13 GBG65930.1 - 0.0015 18.7 20.0 0.0015 18.7 20.0 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Methyltransf_32 PF13679.6 GBG65930.1 - 0.13 12.3 3.4 0.31 11.0 3.4 1.6 1 0 0 1 1 1 0 Methyltransferase domain Spt20 PF12090.8 GBG65930.1 - 2.6 7.6 27.8 5.8 6.4 27.8 1.5 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 GBG65930.1 - 3.5 7.6 6.6 8.4 6.4 6.6 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4746 PF15928.5 GBG65930.1 - 5.4 6.4 6.5 8.6 5.7 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Peptidase_M28 PF04389.17 GBG65932.1 - 6.4e-11 42.3 0.0 1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 RT_RNaseH PF17917.1 GBG65933.1 - 3.1e-22 78.8 0.0 5.7e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG65933.1 - 2.8e-19 69.0 0.0 5.1e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG65933.1 - 4.3e-08 33.4 0.9 1.1e-07 32.1 0.9 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain LapA_dom PF06305.11 GBG65933.1 - 0.29 11.0 3.1 0.18 11.6 0.6 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain BRE1 PF08647.11 GBG65933.1 - 1.8 8.7 6.0 3 8.0 0.2 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase MAP17 PF15807.5 GBG65933.1 - 6.3 7.0 6.0 0.57 10.4 0.1 2.3 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DDE_Tnp_4 PF13359.6 GBG65935.1 - 5.5e-15 55.4 0.0 1.6e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65935.1 - 1.6e-06 27.9 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG65935.1 - 0.017 14.8 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain TAXi_N PF14543.6 GBG65936.1 - 2.5e-16 60.4 0.9 3.8e-16 59.8 0.9 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GBG65936.1 - 1.2e-09 38.1 2.6 1.9e-09 37.4 0.2 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GBG65936.1 - 7e-09 35.7 0.2 1.1e-08 35.0 0.2 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 GBG65937.1 - 3.6e-17 63.2 3.8 5.7e-16 59.3 0.9 2.2 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Asp PF00026.23 GBG65937.1 - 3.1e-09 36.7 0.3 3.1e-09 36.7 0.3 2.3 3 0 0 3 3 3 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GBG65937.1 - 9.4e-09 35.2 0.2 1.6e-08 34.5 0.2 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Gemini_AC4_5_2 PF08464.10 GBG65937.1 - 0.02 14.8 2.1 5.9 6.9 0.2 2.5 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region TAXi_N PF14543.6 GBG65938.1 - 2.5e-16 60.4 0.9 3.8e-16 59.8 0.9 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GBG65938.1 - 1.2e-09 38.1 2.6 1.9e-09 37.4 0.2 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GBG65938.1 - 7e-09 35.7 0.2 1.1e-08 35.0 0.2 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal ZapB PF06005.12 GBG65940.1 - 0.048 14.1 0.2 0.092 13.2 0.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DEK_C PF08766.11 GBG65941.1 - 0.0067 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 DEK C terminal domain ZapB PF06005.12 GBG65943.1 - 0.032 14.7 1.4 0.061 13.8 0.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB DUF2201_N PF13203.6 GBG65943.1 - 0.24 10.9 4.2 0.084 12.5 0.4 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Ribosomal_60s PF00428.19 GBG65943.1 - 0.65 10.6 6.4 1.2 9.7 0.1 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pes-10 PF07149.11 GBG65943.1 - 0.94 8.5 4.0 0.19 10.8 0.5 1.5 2 0 0 2 2 2 0 Pes-10 2-oxoacid_dh PF00198.23 GBG65945.1 - 1.2e-76 257.2 0.1 1.8e-76 256.7 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GBG65945.1 - 2.8e-19 68.7 0.1 7.4e-19 67.4 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GBG65945.1 - 4.7e-15 55.6 0.2 1.2e-14 54.4 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GBG65945.1 - 0.00059 19.6 0.0 0.0095 15.8 0.0 2.9 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.7 GBG65945.1 - 0.088 11.5 0.0 4.1 6.0 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein Ribosom_S12_S23 PF00164.25 GBG65945.1 - 0.094 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S12/S23 T2SSB PF16537.5 GBG65945.1 - 0.1 12.2 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system protein B YgaB PF14182.6 GBG65945.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 YgaB-like protein 2-oxoacid_dh PF00198.23 GBG65946.1 - 3.7e-66 222.9 0.4 2.5e-63 213.6 0.2 2.1 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GBG65946.1 - 2.7e-19 68.8 0.1 7e-19 67.4 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GBG65946.1 - 4.5e-15 55.7 0.2 1.1e-14 54.4 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GBG65946.1 - 0.00055 19.7 0.0 0.009 15.8 0.0 2.9 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.7 GBG65946.1 - 0.08 11.7 0.0 3.9 6.1 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein Ribosom_S12_S23 PF00164.25 GBG65946.1 - 0.089 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S12/S23 T2SSB PF16537.5 GBG65946.1 - 0.096 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system protein B YgaB PF14182.6 GBG65946.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 YgaB-like protein KOW PF00467.29 GBG65947.1 - 2.2e-08 33.8 0.9 2.2e-08 33.8 0.9 2.1 2 0 0 2 2 2 1 KOW motif ribosomal_L24 PF17136.4 GBG65947.1 - 0.0004 20.7 0.7 0.00078 19.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 Radical_SAM PF04055.21 GBG65948.1 - 1.1e-15 58.4 0.1 1.7e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 GBG65948.1 - 4.9e-09 36.6 0.0 1.1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Phyto-Amp PF15438.6 GBG65948.1 - 0.2 11.4 0.1 0.33 10.8 0.1 1.2 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma Kinesin PF00225.23 GBG65950.1 - 4.3e-82 275.7 0.2 4.3e-82 275.7 0.2 3.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GBG65950.1 - 0.00019 21.4 2.0 0.00068 19.6 0.0 3.2 2 0 0 2 2 2 1 Microtubule binding Mad3_BUB1_I_2 PF17014.5 GBG65950.1 - 0.53 10.4 3.5 1.2 9.2 0.2 3.6 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein SAB PF04382.13 GBG65950.1 - 2.4 8.3 15.6 7.3 6.8 1.8 4.8 3 0 0 3 3 3 0 SAB domain Myb_DNA-bind_4 PF13837.6 GBG65952.1 - 2.2e-07 31.2 3.7 3.2e-07 30.6 3.7 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG65952.1 - 0.01 16.1 0.8 0.019 15.3 0.8 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Vps52 PF04129.12 GBG65955.1 - 1.1e-100 337.8 2.2 1.4e-100 337.5 2.2 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 GBG65955.1 - 7.5e-10 37.8 7.6 1.3e-08 33.7 7.6 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec3 APG17 PF04108.12 GBG65955.1 - 0.0025 17.0 0.8 0.0049 16.0 0.8 1.4 1 0 0 1 1 1 1 Autophagy protein Apg17 Cep57_MT_bd PF06657.13 GBG65955.1 - 0.074 13.5 0.1 0.074 13.5 0.1 3.2 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF2848 PF11010.8 GBG65955.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) DUF2018 PF09442.10 GBG65955.1 - 0.71 10.9 3.6 23 6.1 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF2018) COG2 PF06148.11 GBG65955.1 - 0.83 9.7 5.0 0.63 10.1 1.6 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps52 PF04129.12 GBG65957.1 - 1e-59 202.6 3.0 8.6e-59 199.6 1.3 2.3 2 0 0 2 2 2 1 Vps52 / Sac2 family RT_RNaseH_2 PF17919.1 GBG65957.1 - 1e-30 105.7 0.0 2.7e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65957.1 - 5e-30 103.9 0.0 1.6e-29 102.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG65958.1 - 3.9e-06 27.3 0.0 1.2e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG65958.1 - 1.2e-05 25.8 0.1 5.3e-05 23.8 0.1 2.1 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG65958.1 - 0.01 15.6 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG65958.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG65958.1 - 0.11 12.1 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Myb_DNA-bind_4 PF13837.6 GBG65959.1 - 0.051 14.0 3.2 0.053 13.9 0.4 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain NPH3 PF03000.14 GBG65960.1 - 1.2e-29 103.8 0.2 4.4e-29 101.9 0.2 2.0 1 1 0 1 1 1 1 NPH3 family BTB PF00651.31 GBG65960.1 - 0.012 15.8 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain Exonuc_VII_L PF02601.15 GBG65960.1 - 0.015 14.9 8.0 0.025 14.1 8.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 GBG65960.1 - 0.041 13.9 6.7 0.11 12.6 6.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 GBG65960.1 - 0.053 13.6 11.1 0.027 14.5 4.0 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 GBG65960.1 - 0.11 12.6 14.2 0.36 11.0 4.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 GBG65960.1 - 0.14 12.5 9.8 1.7 9.0 1.9 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family ComX PF05952.12 GBG65960.1 - 0.17 11.8 0.0 0.83 9.6 0.0 2.1 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Spc7 PF08317.11 GBG65960.1 - 0.23 10.3 15.0 0.35 9.7 15.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 GBG65960.1 - 0.62 10.7 15.4 4.3 8.0 4.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 GBG65960.1 - 0.95 9.6 9.4 2.3 8.4 9.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DLP_helical PF18709.1 GBG65960.1 - 1.3 8.1 8.6 0.64 9.2 4.1 2.4 2 1 0 3 3 3 0 Dynamin-like helical domain DivIC PF04977.15 GBG65960.1 - 1.9 8.3 13.3 2.6 7.9 1.3 2.8 2 1 1 3 3 3 0 Septum formation initiator DUF2205 PF10224.9 GBG65960.1 - 2.1 8.4 9.6 1.1 9.2 3.5 2.8 1 1 1 2 2 2 0 Short coiled-coil protein Jnk-SapK_ap_N PF09744.9 GBG65960.1 - 5.2 7.3 17.8 21 5.3 17.9 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 GBG65960.1 - 6.2 6.1 9.1 11 5.2 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 GBG65960.1 - 7.9 6.4 18.2 8.1 6.3 6.4 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain Rho_Binding PF08912.11 GBG65960.1 - 8.1 7.3 13.8 7.1 7.5 2.1 2.7 2 0 0 2 2 2 0 Rho Binding Ricin_B_lectin PF00652.22 GBG65961.1 - 0.11 12.7 1.3 0.71 10.1 0.1 2.5 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain NPH3 PF03000.14 GBG65962.1 - 7.8e-31 107.6 0.1 2.8e-30 105.8 0.1 2.0 1 1 0 1 1 1 1 NPH3 family BTB PF00651.31 GBG65962.1 - 0.0055 16.9 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Exonuc_VII_L PF02601.15 GBG65962.1 - 0.061 12.9 10.0 0.11 12.0 10.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit HMMR_N PF15905.5 GBG65962.1 - 0.061 12.8 17.2 0.1 12.0 17.2 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal AAA_23 PF13476.6 GBG65962.1 - 0.43 11.0 8.3 0.69 10.4 8.3 1.3 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 GBG65962.1 - 0.54 10.4 17.7 3 8.0 7.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor DUF1664 PF07889.12 GBG65962.1 - 0.54 10.3 9.1 0.33 11.0 7.0 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) ZapB PF06005.12 GBG65962.1 - 0.6 10.6 20.1 2.1 8.8 4.9 2.6 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 GBG65962.1 - 0.68 10.6 17.9 2.1 9.0 3.7 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 GBG65962.1 - 0.77 8.6 18.7 1.2 8.0 18.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4795 PF16043.5 GBG65962.1 - 1.3 8.6 14.7 12 5.4 11.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) GAS PF13851.6 GBG65962.1 - 1.7 8.0 18.2 1.1 8.6 16.0 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 GBG65962.1 - 2.1 8.6 18.1 5.5 7.2 18.1 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 GBG65962.1 - 2.7 7.3 9.7 5.4 6.3 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 GBG65962.1 - 4.7 7.4 15.0 2.7 8.2 4.2 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 TSC22 PF01166.18 GBG65962.1 - 9.8 6.6 12.8 7 7.0 1.6 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF659 PF04937.15 GBG65963.1 - 3.3e-17 62.8 0.0 4.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Nop14 PF04147.12 GBG65965.1 - 0.017 13.3 3.4 0.021 13.1 3.4 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG65965.1 - 0.15 10.4 7.5 0.18 10.1 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CaATP_NAI PF12515.8 GBG65966.1 - 4.6e-08 32.5 0.3 8e-08 31.8 0.3 1.4 1 0 0 1 1 1 1 Ca2+-ATPase N terminal autoinhibitory domain NPR3 PF03666.13 GBG65966.1 - 3.8e-05 22.7 5.9 4.3e-05 22.5 5.9 1.0 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Mpp10 PF04006.12 GBG65966.1 - 0.00071 18.2 22.6 0.0008 18.0 22.6 1.1 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 GBG65966.1 - 0.00082 17.7 23.8 0.00089 17.6 23.8 1.0 1 0 0 1 1 1 1 Nop14-like family DUF913 PF06025.12 GBG65966.1 - 0.0044 16.1 4.1 0.0045 16.0 4.1 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) SDA1 PF05285.12 GBG65966.1 - 0.0093 15.4 24.1 0.01 15.3 24.1 1.1 1 0 0 1 1 1 1 SDA1 Pox_Ag35 PF03286.14 GBG65966.1 - 0.013 15.4 17.3 0.017 14.9 17.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDHD PF02862.17 GBG65966.1 - 0.015 15.5 1.4 0.016 15.4 1.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF5523 PF17661.1 GBG65966.1 - 0.017 14.9 23.5 0.021 14.5 23.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Afi1 PF07792.12 GBG65966.1 - 0.017 15.6 7.2 0.021 15.3 7.2 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SpoIIP PF07454.11 GBG65966.1 - 0.023 14.2 10.8 0.027 13.9 10.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF5427 PF10310.9 GBG65966.1 - 0.024 13.6 11.1 0.029 13.3 11.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CPSF100_C PF13299.6 GBG65966.1 - 0.037 14.2 9.6 0.05 13.8 9.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BUD22 PF09073.10 GBG65966.1 - 0.039 13.3 23.6 0.048 13.0 23.6 1.1 1 0 0 1 1 1 0 BUD22 AAR2 PF05282.11 GBG65966.1 - 0.048 13.1 2.4 0.053 12.9 2.4 1.1 1 0 0 1 1 1 0 AAR2 protein DUF740 PF05340.12 GBG65966.1 - 0.05 12.3 10.2 0.055 12.2 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Coilin_N PF15862.5 GBG65966.1 - 0.06 13.2 6.7 0.07 12.9 6.7 1.2 1 0 0 1 1 1 0 Coilin N-terminus TRAP_alpha PF03896.16 GBG65966.1 - 0.064 12.4 15.0 0.083 12.1 15.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 GBG65966.1 - 0.071 13.5 9.1 0.095 13.1 9.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 MRP-S26 PF14943.6 GBG65966.1 - 0.08 12.9 20.7 0.14 12.1 20.7 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PPP4R2 PF09184.11 GBG65966.1 - 0.082 12.5 22.8 0.088 12.4 22.8 1.1 1 0 0 1 1 1 0 PPP4R2 Vfa1 PF08432.10 GBG65966.1 - 0.12 12.7 15.5 0.14 12.4 15.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 GBG65966.1 - 0.12 11.3 31.8 0.15 11.0 31.8 1.1 1 0 0 1 1 1 0 Paf1 MRNIP PF15749.5 GBG65966.1 - 0.15 12.8 9.7 0.24 12.1 9.7 1.5 1 0 0 1 1 1 0 MRN-interacting protein Saw1 PF11561.8 GBG65966.1 - 0.16 11.5 7.3 0.23 11.0 7.3 1.2 1 0 0 1 1 1 0 Single strand annealing-weakened 1 TFB6 PF17110.5 GBG65966.1 - 0.17 11.6 11.3 0.27 11.0 11.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Dynamin_N PF00350.23 GBG65966.1 - 0.18 11.9 0.7 0.2 11.7 0.7 1.2 1 0 0 1 1 1 0 Dynamin family Laps PF10169.9 GBG65966.1 - 0.2 12.3 14.3 0.26 11.9 14.3 1.1 1 0 0 1 1 1 0 Learning-associated protein AIF_C PF14721.6 GBG65966.1 - 0.33 11.3 8.8 0.5 10.7 8.8 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 GBG65966.1 - 0.35 10.6 10.3 0.43 10.3 10.3 1.1 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 GBG65966.1 - 0.4 10.7 2.0 0.51 10.4 2.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 GBG65966.1 - 0.41 8.9 24.7 0.49 8.6 24.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 GBG65966.1 - 0.47 9.8 19.5 0.58 9.5 19.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BSMAP PF12280.8 GBG65966.1 - 0.6 10.3 2.0 0.75 10.0 2.0 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein AAA_23 PF13476.6 GBG65966.1 - 0.65 10.5 14.1 0.8 10.2 14.1 1.2 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 GBG65966.1 - 0.77 8.9 7.7 0.97 8.6 7.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 GBG65966.1 - 0.78 9.2 9.5 1 8.8 9.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Spore_coat_CotO PF14153.6 GBG65966.1 - 0.81 9.6 21.7 1 9.2 21.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 GBG65966.1 - 0.83 8.4 11.9 0.94 8.2 11.9 1.1 1 0 0 1 1 1 0 Presenilin rRNA_processing PF08524.11 GBG65966.1 - 0.85 9.6 23.9 1.1 9.2 23.9 1.1 1 0 0 1 1 1 0 rRNA processing RNA_polI_A34 PF08208.11 GBG65966.1 - 0.86 9.7 24.3 1.1 9.3 24.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PPL5 PF18168.1 GBG65966.1 - 0.94 8.7 7.9 1.1 8.5 7.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 GBG65966.1 - 0.95 9.2 23.4 1.2 8.9 23.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 GBG65966.1 - 1 8.3 5.0 1.2 8.0 5.0 1.1 1 0 0 1 1 1 0 CLN3 protein AAA_11 PF13086.6 GBG65966.1 - 1.1 9.0 6.9 1.2 8.9 6.9 1.1 1 0 0 1 1 1 0 AAA domain RP-C_C PF11800.8 GBG65966.1 - 1.1 9.3 7.5 1.4 9.0 7.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2457 PF10446.9 GBG65966.1 - 1.2 8.1 31.1 1.6 7.8 31.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VIR_N PF15912.5 GBG65966.1 - 1.3 8.6 19.8 1.6 8.2 19.8 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal PI3K_1B_p101 PF10486.9 GBG65966.1 - 1.3 6.7 9.9 1.6 6.4 9.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3306 PF11748.8 GBG65966.1 - 1.4 9.8 15.4 2.1 9.2 15.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) SAPS PF04499.15 GBG65966.1 - 1.4 7.6 10.9 1.5 7.5 10.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FYDLN_acid PF09538.10 GBG65966.1 - 1.5 9.5 20.3 3 8.6 20.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) eIF-3c_N PF05470.12 GBG65966.1 - 1.6 6.9 14.4 1.9 6.7 14.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Serinc PF03348.15 GBG65966.1 - 1.9 7.3 5.0 2.1 7.1 5.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PAF PF15715.5 GBG65966.1 - 2.1 8.9 14.9 3.2 8.3 14.9 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Peroxin-13_N PF04088.13 GBG65966.1 - 2.1 8.6 3.3 3.8 7.8 3.3 1.4 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Eapp_C PF10238.9 GBG65966.1 - 2.5 8.1 10.0 4.1 7.5 10.0 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein FancD2 PF14631.6 GBG65966.1 - 2.5 5.4 7.2 2.6 5.3 7.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF719 PF05334.13 GBG65966.1 - 2.8 8.1 11.6 4.6 7.4 11.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF2151 PF10221.9 GBG65966.1 - 2.9 6.4 12.1 3.5 6.1 12.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator PTPRCAP PF15713.5 GBG65966.1 - 3 8.1 29.9 0.67 10.2 26.6 1.6 2 0 0 2 2 1 0 Protein tyrosine phosphatase receptor type C-associated RPN2_C PF18004.1 GBG65966.1 - 3.2 7.7 24.5 4.8 7.1 24.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain ALMT PF11744.8 GBG65966.1 - 3.8 6.2 4.5 4.5 6.0 4.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 GBG65966.1 - 4.4 6.2 7.5 5.1 6.0 7.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Tim54 PF11711.8 GBG65966.1 - 4.8 5.9 21.0 6.5 5.4 21.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Smg8_Smg9 PF10220.9 GBG65966.1 - 4.9 5.3 7.2 5.3 5.2 7.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 ORC_WH_C PF18137.1 GBG65966.1 - 5 7.2 16.1 7.7 6.6 16.1 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal FGF-BP1 PF06473.12 GBG65966.1 - 5.1 6.9 12.5 6.7 6.5 12.5 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) CENP-N PF05238.13 GBG65966.1 - 5.4 6.2 10.4 6.6 5.9 10.4 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like FAM60A PF15396.6 GBG65966.1 - 6 6.8 7.4 7.7 6.5 7.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RINGv PF12906.7 GBG65967.1 - 6.2e-07 29.5 5.3 1.2e-06 28.5 5.3 1.6 1 0 0 1 1 1 1 RING-variant domain DUF3792 PF12670.7 GBG65967.1 - 0.33 11.1 4.7 0.47 10.6 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) zf-RING-like PF08746.11 GBG65967.1 - 1.6 9.1 4.8 3.5 8.0 4.8 1.6 1 0 0 1 1 1 0 RING-like domain GRP PF07172.11 GBG65967.1 - 2.6 8.8 21.4 9.2 7.0 21.4 2.0 1 0 0 1 1 1 0 Glycine rich protein family E1-E2_ATPase PF00122.20 GBG65968.1 - 9.8e-20 70.8 0.5 9.8e-20 70.8 0.5 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 GBG65968.1 - 3.1e-12 46.0 0.0 5.8e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF3792 PF12670.7 GBG65968.1 - 0.06 13.5 0.3 0.088 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) E1-E2_ATPase PF00122.20 GBG65969.1 - 3.7e-07 29.8 0.1 3.7e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Laminin_II PF06009.12 GBG65970.1 - 0.034 14.2 0.5 0.2 11.6 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 GBG65970.1 - 0.12 12.7 0.3 0.12 12.7 0.3 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 GBG65970.1 - 0.74 9.9 3.0 7.7 6.6 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 GBG65970.1 - 4.7 7.8 9.0 0.64 10.6 2.7 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Macoilin PF09726.9 GBG65970.1 - 6.2 5.2 13.7 9.6 4.6 13.7 1.4 1 0 0 1 1 1 0 Macoilin family Sugar_tr PF00083.24 GBG65971.1 - 9.3e-82 275.3 13.1 1.5e-38 132.8 0.3 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 GBG65971.1 - 3.3e-25 88.8 36.0 6.7e-21 74.6 4.3 3.5 2 1 2 4 4 4 3 Major Facilitator Superfamily MFS_2 PF13347.6 GBG65971.1 - 2e-05 23.3 13.0 0.015 13.9 0.8 3.3 3 1 0 3 3 3 3 MFS/sugar transport protein Cation_ATPase PF13246.6 GBG65971.1 - 6.4e-05 23.0 0.1 0.00014 21.9 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) RT_RNaseH_2 PF17919.1 GBG65972.1 - 1.1e-30 105.6 0.1 6.7e-30 103.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65972.1 - 4.6e-26 91.1 0.1 1.3e-25 89.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65972.1 - 1.8e-12 47.3 0.2 4.5e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65972.1 - 0.0097 16.0 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG65972.1 - 0.011 15.9 1.1 0.066 13.5 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein BAF250_C PF12031.8 GBG65972.1 - 0.09 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa zf-CCHC_3 PF13917.6 GBG65972.1 - 0.24 11.4 1.5 0.6 10.1 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Hydrolase PF00702.26 GBG65973.1 - 2.6e-17 63.8 0.6 8.9e-17 62.1 0.6 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GBG65973.1 - 8.6e-07 28.9 0.8 1.3e-05 25.0 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GBG65973.1 - 0.0042 17.5 0.0 0.007 16.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DAGK_cat PF00781.24 GBG65973.1 - 0.017 14.7 0.1 0.17 11.5 0.0 2.3 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain DUF3377 PF11857.8 GBG65974.1 - 2.3 8.2 0.0 2.3 8.2 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3377) RT_RNaseH_2 PF17919.1 GBG65975.1 - 4.1e-24 84.5 0.0 1.4e-23 82.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG65975.1 - 2.8e-22 79.0 0.0 8.6e-22 77.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG65975.1 - 2.7e-21 76.1 0.1 5.4e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG65975.1 - 3.1e-17 62.4 0.5 3.1e-17 62.4 0.5 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG65975.1 - 1.5e-09 38.0 0.0 5e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG65975.1 - 1e-07 31.8 0.0 2.9e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG65975.1 - 3.2e-07 30.9 0.0 8.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65975.1 - 1.3e-06 28.9 0.0 3.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Cation_ATPase_C PF00689.21 GBG65975.1 - 0.0002 21.1 1.8 0.00034 20.4 1.8 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Retrotrans_gag PF03732.17 GBG65975.1 - 0.00026 21.2 5.0 0.25 11.6 0.1 3.9 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG65975.1 - 0.00032 20.5 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG65975.1 - 0.055 13.7 0.0 0.055 13.7 0.0 2.0 2 0 0 2 2 1 0 H2C2 zinc finger rve PF00665.26 GBG65976.1 - 1.7e-17 63.7 0.0 3.7e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG65976.1 - 3.5e-14 52.6 0.3 1.1e-13 51.0 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG65976.1 - 0.0012 18.6 0.0 0.0031 17.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG65976.1 - 0.051 13.8 0.4 0.13 12.5 0.4 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Torsin PF06309.11 GBG65976.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Torsin Integrase_H2C2 PF17921.1 GBG65978.1 - 1.6e-29 101.7 4.2 1.3e-16 60.4 0.2 2.5 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG65978.1 - 4.1e-18 65.7 0.0 1.2e-10 41.6 0.0 2.4 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG65978.1 - 0.00029 21.0 0.1 0.15 12.3 0.0 2.8 2 0 0 2 2 2 2 H2C2 zinc finger IL34 PF15036.6 GBG65978.1 - 0.019 15.0 0.5 0.33 11.0 0.1 2.2 2 0 0 2 2 2 0 Interleukin 34 Cys_rich_CPCC PF14206.6 GBG65978.1 - 0.028 14.2 0.2 7.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich CPCC CxC2 PF18803.1 GBG65978.1 - 0.03 14.5 0.1 6 7.1 0.0 3.6 2 2 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases Synaptobrevin PF00957.21 GBG65978.1 - 0.051 13.4 0.7 5 7.0 0.1 2.3 2 0 0 2 2 2 0 Synaptobrevin Tubulin PF00091.25 GBG65979.1 - 2.8e-66 223.5 0.0 3.9e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG65979.1 - 2.1e-50 170.1 0.1 3.2e-50 169.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GBG65979.1 - 0.0066 16.2 0.0 0.024 14.3 0.0 2.0 3 0 0 3 3 3 1 Tubulin domain DUF3347 PF11827.8 GBG65980.1 - 0.66 10.1 2.8 2.2 8.4 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) dCMP_cyt_deam_1 PF00383.23 GBG65981.1 - 9.8e-23 80.0 0.2 1.7e-22 79.2 0.2 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GBG65981.1 - 2e-19 69.7 0.2 2.7e-19 69.3 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 GBG65981.1 - 0.018 15.1 0.7 0.031 14.4 0.7 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 GBG65981.1 - 0.072 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 GBG65981.1 - 0.1 12.6 0.3 0.18 11.8 0.3 1.3 1 0 0 1 1 1 0 APOBEC2 FAM24 PF15193.6 GBG65981.1 - 0.75 10.6 5.1 0.3 11.9 2.1 1.8 2 0 0 2 2 2 0 FAM24 family Myb_DNA-bind_4 PF13837.6 GBG65982.1 - 3.8e-07 30.4 4.3 1.3e-06 28.7 2.2 2.4 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain FliJ PF02050.16 GBG65982.1 - 1 9.6 4.9 0.19 11.9 0.4 2.0 2 1 0 2 2 2 0 Flagellar FliJ protein DDE_Tnp_4 PF13359.6 GBG65984.1 - 2.9e-32 111.5 0.0 4.9e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65984.1 - 1.1e-16 61.0 0.0 2.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG65984.1 - 0.0018 18.0 1.6 0.93 9.1 0.0 3.0 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG65984.1 - 0.017 15.4 0.6 0.28 11.6 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain PAP2 PF01569.21 GBG65985.1 - 2e-26 92.4 1.0 1e-25 90.1 0.5 2.1 2 0 0 2 2 2 1 PAP2 superfamily GT87 PF09594.10 GBG65985.1 - 0.0022 17.7 5.1 0.019 14.7 5.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 87 YhhN PF07947.14 GBG65985.1 - 0.072 12.7 1.5 0.27 10.8 0.1 2.2 3 0 0 3 3 3 0 YhhN family PAP2_3 PF14378.6 GBG65985.1 - 0.19 11.4 4.4 0.98 9.1 3.1 2.5 1 1 0 1 1 1 0 PAP2 superfamily FtsX PF02687.21 GBG65985.1 - 0.3 11.6 2.2 31 5.1 0.0 3.4 3 1 0 3 3 3 0 FtsX-like permease family DUF2976 PF11190.8 GBG65985.1 - 1.1 9.1 3.6 6.2 6.7 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) rRNA_processing PF08524.11 GBG65986.1 - 0.00011 22.2 22.5 0.00011 22.2 22.5 4.9 4 2 1 5 5 5 2 rRNA processing DUF1499 PF07386.11 GBG65987.1 - 4e-23 82.2 0.0 4.2e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) Asp_protease_2 PF13650.6 GBG65988.1 - 0.00044 20.8 0.0 0.0016 19.0 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG65988.1 - 0.011 16.2 0.0 0.077 13.6 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease zinc_ribbon_13 PF09855.9 GBG65988.1 - 0.087 13.0 10.7 47 4.3 0.1 7.1 7 1 1 8 8 8 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Flagellin_C PF00700.21 GBG65988.1 - 0.18 12.2 3.3 6.7 7.2 0.2 3.3 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region Dockerin_1 PF00404.18 GBG65988.1 - 0.42 10.8 2.9 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Dockerin type I domain DUF3439 PF11921.8 GBG65988.1 - 8.8 6.3 8.4 2.3 8.2 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PsbP PF01789.16 GBG65989.1 - 4.2e-43 147.2 0.0 6.6e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 PsbP Rotamase_3 PF13616.6 GBG65990.1 - 5e-15 56.1 0.0 1e-14 55.0 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 GBG65990.1 - 1.1e-12 48.7 0.0 2.7e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rhodanese PF00581.20 GBG65990.1 - 4.1e-05 24.0 0.0 0.00011 22.7 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Aminotran_5 PF00266.19 GBG65991.1 - 3.2e-56 190.9 0.0 3.8e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V RVT_1 PF00078.27 GBG65992.1 - 2.5e-28 99.1 0.2 3.5e-28 98.6 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG65992.1 - 0.0021 17.8 0.1 0.0045 16.8 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease DUF4916 PF16262.5 GBG65992.1 - 0.019 14.5 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) BSP_II PF05432.11 GBG65993.1 - 0.0012 18.6 13.3 0.0013 18.5 13.3 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF2052 PF09747.9 GBG65993.1 - 0.0056 16.8 7.8 0.0059 16.8 7.8 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF4642 PF15484.6 GBG65993.1 - 0.011 16.0 4.9 0.012 15.8 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) RXT2_N PF08595.11 GBG65993.1 - 0.028 14.4 3.7 0.031 14.3 3.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 GBG65993.1 - 0.059 13.2 5.8 0.061 13.1 5.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 GBG65993.1 - 0.072 11.2 12.4 0.068 11.3 12.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 GBG65993.1 - 0.089 12.5 6.5 0.098 12.3 6.5 1.2 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 GBG65993.1 - 0.15 10.3 11.7 0.14 10.3 11.7 1.0 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 GBG65993.1 - 0.19 10.7 12.1 0.19 10.7 12.1 1.0 1 0 0 1 1 1 0 Paf1 DUF4746 PF15928.5 GBG65993.1 - 0.2 11.1 10.2 0.22 10.9 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Radial_spoke PF04712.12 GBG65993.1 - 0.23 10.4 13.2 0.23 10.4 13.2 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein CENP-B_dimeris PF09026.10 GBG65993.1 - 0.27 11.6 13.9 0.37 11.2 13.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop53 PF07767.11 GBG65993.1 - 0.3 10.4 10.2 0.32 10.4 10.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CobT PF06213.12 GBG65993.1 - 0.35 10.2 10.4 0.36 10.2 10.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF5523 PF17661.1 GBG65993.1 - 0.35 10.5 10.5 0.4 10.3 10.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CDC45 PF02724.14 GBG65993.1 - 0.4 8.9 11.2 0.43 8.8 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 GBG65993.1 - 0.43 10.5 5.6 0.42 10.5 5.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Importin_rep_4 PF18808.1 GBG65993.1 - 0.44 10.8 6.3 0.6 10.4 6.3 1.2 1 0 0 1 1 1 0 Importin repeat S-antigen PF05756.11 GBG65993.1 - 0.79 10.1 9.1 1 9.8 9.1 1.2 1 0 0 1 1 1 0 S-antigen protein NOA36 PF06524.12 GBG65993.1 - 0.83 8.9 13.0 0.98 8.7 13.0 1.1 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 GBG65993.1 - 0.85 9.3 4.2 0.87 9.3 4.2 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4637 PF15470.6 GBG65993.1 - 0.89 9.3 12.4 1.1 9.0 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pns11_12 PF17464.2 GBG65993.1 - 0.96 9.1 3.1 1.1 9.0 3.1 1.2 1 0 0 1 1 1 0 Non-structural protein 11 and 12 PI3K_1B_p101 PF10486.9 GBG65993.1 - 1.4 6.6 4.7 1.5 6.5 4.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2457 PF10446.9 GBG65993.1 - 1.4 7.9 14.8 1.5 7.9 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.16 GBG65993.1 - 2.4 7.3 7.2 2.7 7.1 7.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cnd2 PF05786.14 GBG65993.1 - 4.9 5.7 8.8 4.9 5.7 8.8 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 GOLD_2 PF13897.6 GBG65993.1 - 5.5 7.5 7.2 6.2 7.3 7.2 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking HSP90 PF00183.18 GBG65993.1 - 8.4 5.2 11.0 8.6 5.1 11.0 1.0 1 0 0 1 1 1 0 Hsp90 protein G-patch_2 PF12656.7 GBG65994.1 - 4.8e-19 68.2 0.1 4.8e-19 68.2 0.1 3.5 4 0 0 4 4 4 1 G-patch domain KN17_SH3 PF18131.1 GBG65994.1 - 1.6e-06 28.1 0.2 5.6e-06 26.4 0.2 1.9 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain KOW PF00467.29 GBG65994.1 - 2.5e-06 27.2 0.3 0.2 11.7 0.0 3.5 3 0 0 3 3 3 2 KOW motif G-patch PF01585.23 GBG65994.1 - 0.00012 21.9 0.1 0.00012 21.9 0.1 2.4 2 0 0 2 2 2 1 G-patch domain Orf78 PF06024.12 GBG65995.1 - 0.21 11.9 4.6 0.39 11.0 4.6 1.5 1 1 0 1 1 1 0 Orf78 (ac78) Cnd2 PF05786.14 GBG65995.1 - 0.33 9.6 6.7 0.34 9.5 6.7 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF3295 PF11702.8 GBG65995.1 - 0.33 10.3 7.4 0.33 10.2 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) SKN1 PF03935.15 GBG65995.1 - 0.46 8.8 3.0 0.57 8.5 3.0 1.0 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) RRN3 PF05327.11 GBG65995.1 - 1.9 7.0 7.1 2 6.8 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 GBG65995.1 - 2.1 7.9 6.7 2.6 7.6 6.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Spc7_N PF15402.6 GBG65995.1 - 5.4 5.1 10.4 5.9 5.0 10.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RXT2_N PF08595.11 GBG65995.1 - 6.8 6.7 6.2 10 6.1 6.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DDE_Tnp_4 PF13359.6 GBG65996.1 - 2.1e-15 56.7 0.0 7.8e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG65996.1 - 8.5e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DUF659 PF04937.15 GBG65998.1 - 3.3e-09 36.8 0.0 4.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG66000.1 - 2e-07 31.3 0.1 3.3e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG66000.1 - 0.0022 18.0 0.6 0.0038 17.3 0.6 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Dsh_C PF12316.8 GBG66002.1 - 3 8.2 9.2 1.3 9.4 6.6 1.6 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal LAP1C PF05609.12 GBG66004.1 - 3.5 6.6 19.2 4.5 6.3 19.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Carboxyl_trans PF01039.22 GBG66006.1 - 1.1e-179 598.2 0.0 1.4e-179 597.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain RVT_1 PF00078.27 GBG66011.1 - 0.018 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cob_adeno_trans PF01923.18 GBG66015.1 - 7.9e-56 188.7 0.0 1e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase FUR PF01475.19 GBG66015.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family DUF659 PF04937.15 GBG66016.1 - 5.8e-24 84.7 0.0 1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG66017.1 - 1.3e-32 113.1 0.2 6.3e-29 101.1 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66017.1 - 4.5e-19 68.7 0.1 9.4e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66017.1 - 2.6e-17 62.6 0.1 5.4e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66017.1 - 7e-14 52.1 0.0 1.9e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG66017.1 - 3.1e-11 43.2 0.0 7.2e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG66017.1 - 1.5e-05 24.8 0.0 3.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG66017.1 - 7.5e-05 23.2 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66017.1 - 9.2e-05 23.0 0.0 0.0002 21.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG66019.1 - 2.8e-39 134.9 0.0 4e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nterm_IS4 PF13006.7 GBG66019.1 - 0.04 14.1 0.3 28 5.0 0.2 3.3 2 1 1 3 3 3 0 Insertion element 4 transposase N-terminal AAA_11 PF13086.6 GBG66020.1 - 1.7e-55 188.6 7.8 2.2e-54 185.0 7.8 2.3 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 GBG66020.1 - 7.2e-39 133.5 0.9 1.5e-25 90.0 0.4 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 GBG66020.1 - 1e-13 51.5 2.8 1.9e-09 37.5 0.1 3.0 3 0 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 GBG66020.1 - 1.5e-09 38.0 0.1 2.9e-05 23.9 0.0 2.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 GBG66020.1 - 5.6e-09 36.5 3.8 4.2e-08 33.6 3.8 2.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 GBG66020.1 - 4e-06 26.8 1.3 0.022 14.6 0.2 2.5 2 0 0 2 2 2 2 Helicase AAA PF00004.29 GBG66020.1 - 2.3e-05 24.8 1.5 0.00015 22.2 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG66020.1 - 7.8e-05 23.0 0.7 0.02 15.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 GBG66020.1 - 0.00021 21.3 0.3 0.0031 17.6 0.3 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 GBG66020.1 - 0.00039 20.2 0.3 0.0025 17.6 0.0 2.3 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain PIF1 PF05970.14 GBG66020.1 - 0.0009 18.5 0.0 0.083 12.0 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase AAA_16 PF13191.6 GBG66020.1 - 0.0017 18.8 2.6 0.014 15.8 2.6 2.4 1 1 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 GBG66020.1 - 0.0022 17.5 0.1 0.01 15.3 0.1 2.2 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.6 GBG66020.1 - 0.0026 17.4 3.6 0.1 12.2 3.6 2.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 GBG66020.1 - 0.0043 16.4 2.0 0.051 12.9 0.0 2.8 3 0 0 3 3 3 1 KaiC DEAD PF00270.29 GBG66020.1 - 0.0045 16.8 5.6 0.032 14.0 5.6 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_33 PF13671.6 GBG66020.1 - 0.0052 17.0 0.8 0.029 14.5 0.5 2.6 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 GBG66020.1 - 0.0052 16.1 5.5 0.57 9.3 0.3 3.1 3 1 0 3 3 2 2 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 GBG66020.1 - 0.0055 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD-helicase PF00580.21 GBG66020.1 - 0.0087 15.6 2.9 0.038 13.5 2.9 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Glyco_transf_21 PF13506.6 GBG66020.1 - 0.014 14.9 0.1 0.045 13.2 0.0 1.9 2 0 0 2 2 1 0 Glycosyl transferase family 21 DnaB_C PF03796.15 GBG66020.1 - 0.014 14.7 2.3 0.14 11.5 0.1 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 GBG66020.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD_C_2 PF13538.6 GBG66020.1 - 0.02 14.7 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Flavi_DEAD PF07652.14 GBG66020.1 - 0.022 14.7 1.8 1.6 8.7 0.4 2.6 2 1 0 2 2 2 0 Flavivirus DEAD domain cobW PF02492.19 GBG66020.1 - 0.025 14.2 0.4 0.063 12.9 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 GBG66020.1 - 0.026 14.3 0.0 0.096 12.4 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 GBG66020.1 - 0.031 14.2 1.4 0.44 10.5 0.1 2.5 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 GBG66020.1 - 0.032 14.2 0.1 0.081 12.9 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Glycos_transf_2 PF00535.26 GBG66020.1 - 0.038 13.8 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mg_chelatase PF01078.21 GBG66020.1 - 0.041 13.3 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 GBG66020.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 GBG66020.1 - 0.067 12.9 0.1 0.81 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain RRP36 PF06102.12 GBG66020.1 - 0.092 12.7 3.9 0.19 11.7 3.9 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 CobA_CobO_BtuR PF02572.15 GBG66020.1 - 0.11 12.8 0.6 11 6.2 0.1 2.6 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Nup153 PF08604.10 GBG66020.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup153-like AAA_5 PF07728.14 GBG66020.1 - 0.12 12.4 0.1 1 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zot PF05707.12 GBG66020.1 - 0.16 11.6 0.4 0.71 9.5 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) CSN5_C PF18323.1 GBG66020.1 - 0.2 12.6 3.4 0.54 11.2 3.4 1.7 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF1269 PF06897.12 GBG66020.1 - 0.59 10.4 2.6 32 4.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) AAA_11 PF13086.6 GBG66021.1 - 2e-56 191.7 6.1 3.6e-56 190.9 6.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 GBG66021.1 - 6.2e-39 133.7 0.9 1.5e-25 90.0 0.4 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 GBG66021.1 - 1.2e-12 47.9 7.4 1.1e-10 41.5 6.2 3.0 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 GBG66021.1 - 1.5e-09 37.9 0.1 2.6e-05 24.1 0.0 2.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 GBG66021.1 - 5.6e-09 36.5 4.3 3.6e-08 33.9 4.3 2.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 GBG66021.1 - 4.3e-06 26.7 1.7 0.0011 18.9 1.7 2.5 1 1 0 1 1 1 1 Helicase AAA PF00004.29 GBG66021.1 - 3.5e-05 24.3 2.3 0.00041 20.8 2.3 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG66021.1 - 6e-05 23.3 1.1 0.0063 16.8 1.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG66021.1 - 7.3e-05 23.2 1.2 0.00021 21.7 1.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 GBG66021.1 - 9.6e-05 22.4 0.0 0.00044 20.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 GBG66021.1 - 0.00032 20.5 0.3 0.0021 17.8 0.0 2.4 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain PIF1 PF05970.14 GBG66021.1 - 0.00068 18.9 0.0 0.059 12.5 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase AAA_25 PF13481.6 GBG66021.1 - 0.0016 18.1 3.7 0.03 13.9 3.7 2.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 GBG66021.1 - 0.002 17.7 0.1 0.0084 15.6 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 GBG66021.1 - 0.0036 17.5 0.9 0.019 15.1 0.6 2.5 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 GBG66021.1 - 0.004 16.5 6.1 0.024 13.9 2.3 3.0 2 1 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 GBG66021.1 - 0.0047 16.3 2.6 0.018 14.4 2.3 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain T2SSE PF00437.20 GBG66021.1 - 0.005 15.9 0.0 0.01 14.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD-helicase PF00580.21 GBG66021.1 - 0.0054 16.3 3.6 0.016 14.7 3.5 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 GBG66021.1 - 0.0082 16.1 0.4 1.2 9.1 0.2 2.6 2 0 0 2 2 2 1 Flavivirus DEAD domain DEAD PF00270.29 GBG66021.1 - 0.0093 15.8 6.8 0.064 13.0 6.8 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 GBG66021.1 - 0.012 14.9 4.2 0.026 13.9 1.8 2.6 2 1 0 2 2 2 0 KaiC Glyco_transf_21 PF13506.6 GBG66021.1 - 0.013 15.0 0.1 0.043 13.3 0.0 2.0 2 0 0 2 2 1 0 Glycosyl transferase family 21 UvrD_C_2 PF13538.6 GBG66021.1 - 0.019 14.8 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain cobW PF02492.19 GBG66021.1 - 0.02 14.5 0.3 0.056 13.0 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 GBG66021.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 GBG66021.1 - 0.022 14.5 0.1 0.078 12.7 0.0 2.0 2 0 0 2 2 1 0 IstB-like ATP binding protein TIP49 PF06068.13 GBG66021.1 - 0.025 13.8 1.5 0.059 12.6 1.5 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 GBG66021.1 - 0.027 14.4 1.4 0.41 10.5 0.1 2.5 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 GBG66021.1 - 0.03 14.3 0.1 0.077 13.0 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Glycos_transf_2 PF00535.26 GBG66021.1 - 0.035 13.9 0.0 0.13 12.1 0.0 2.1 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mg_chelatase PF01078.21 GBG66021.1 - 0.039 13.3 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GBG66021.1 - 0.042 13.6 0.2 0.17 11.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 GBG66021.1 - 0.05 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 GBG66021.1 - 0.064 12.9 1.6 0.19 11.3 0.8 2.1 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain RRP36 PF06102.12 GBG66021.1 - 0.084 12.8 3.9 0.18 11.8 3.9 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 AAA_5 PF07728.14 GBG66021.1 - 0.095 12.7 0.0 0.84 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Nup153 PF08604.10 GBG66021.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup153-like Zot PF05707.12 GBG66021.1 - 0.13 11.9 0.2 0.64 9.6 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) CSN5_C PF18323.1 GBG66021.1 - 0.18 12.7 3.4 0.51 11.3 3.4 1.8 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain CobA_CobO_BtuR PF02572.15 GBG66021.1 - 0.19 12.0 1.9 11 6.3 1.9 2.6 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ATPase_2 PF01637.18 GBG66021.1 - 0.23 11.4 1.1 4.8 7.0 1.4 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea DUF1269 PF06897.12 GBG66021.1 - 0.55 10.5 2.8 28 5.1 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1269) PP2 PF14299.6 GBG66022.1 - 2e-16 60.3 0.0 2.1e-12 47.3 0.1 2.2 2 0 0 2 2 2 2 Phloem protein 2 F-box PF00646.33 GBG66022.1 - 0.00023 20.9 8.0 0.00066 19.5 0.0 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GBG66022.1 - 0.0031 17.4 0.2 0.0079 16.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like RT_RNaseH PF17917.1 GBG66024.1 - 3.1e-22 78.8 0.0 6.2e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66024.1 - 1.4e-20 73.1 0.0 3e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66024.1 - 1.1e-14 54.2 0.2 3.4e-14 52.7 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG66024.1 - 2.6e-11 43.5 0.0 5.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG66024.1 - 3e-05 24.2 0.0 8.5e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG66024.1 - 0.00074 20.1 0.1 0.0019 18.8 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66024.1 - 0.0036 17.8 0.1 0.0087 16.6 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG66024.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger FlaC_arch PF05377.11 GBG66024.1 - 0.55 10.7 2.2 4 7.9 0.3 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DLH PF01738.18 GBG66025.1 - 0.00065 19.3 0.3 0.004 16.7 0.3 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family RVT_1 PF00078.27 GBG66026.1 - 1.4e-30 106.5 0.1 1.8e-30 106.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arf PF00025.21 GBG66027.1 - 1e-62 210.6 0.0 1.2e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GBG66027.1 - 1.9e-10 40.5 0.0 1.3e-06 27.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GBG66027.1 - 1.1e-07 32.1 0.0 2.4e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GBG66027.1 - 2.8e-07 30.2 0.0 4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GBG66027.1 - 4.3e-07 29.7 0.0 5.5e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GBG66027.1 - 5.3e-06 26.5 0.0 7.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 GBG66027.1 - 0.00016 21.4 0.0 0.00035 20.3 0.0 1.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 GBG66027.1 - 0.0092 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Antibiotic_NAT PF02522.14 GBG66027.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase cobW PF02492.19 GBG66027.1 - 0.2 11.2 0.0 3.6 7.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pro_isomerase PF00160.21 GBG66028.1 - 3e-39 134.8 0.1 3.5e-39 134.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BAG PF02179.16 GBG66030.1 - 8.9e-07 29.3 3.4 1.4e-06 28.6 3.4 1.3 1 0 0 1 1 1 1 BAG domain BAG PF02179.16 GBG66031.1 - 5.3e-07 30.0 3.4 8.1e-07 29.4 3.4 1.2 1 0 0 1 1 1 1 BAG domain Latarcin PF10279.9 GBG66031.1 - 0.23 11.9 0.6 0.56 10.7 0.6 1.7 1 1 0 1 1 1 0 Latarcin precursor TPX2_importin PF12214.8 GBG66033.1 - 2.7e-51 174.1 54.3 3.7e-23 82.5 3.2 6.6 5 1 1 6 6 6 5 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 GBG66033.1 - 3.3e-09 36.9 8.9 3.3e-09 36.9 8.9 6.9 6 0 0 6 6 6 2 Targeting protein for Xklp2 (TPX2) Aurora-A_bind PF09041.10 GBG66033.1 - 0.015 15.3 3.5 0.039 14.0 3.5 1.6 1 0 0 1 1 1 0 Aurora-A binding TMEM234 PF10639.9 GBG66034.1 - 0.088 12.9 1.2 0.11 12.6 1.2 1.1 1 0 0 1 1 1 0 Putative transmembrane family 234 BT1 PF03092.16 GBG66036.1 - 2.3e-28 98.8 0.9 2.9e-28 98.4 0.9 1.1 1 0 0 1 1 1 1 BT1 family PUCC PF03209.15 GBG66036.1 - 0.052 12.6 0.1 0.072 12.1 0.1 1.2 1 0 0 1 1 1 0 PUCC protein ThrE_2 PF12821.7 GBG66036.1 - 0.057 13.6 1.2 0.07 13.3 0.3 1.5 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE Transgly PF00912.22 GBG66036.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase PAS_5 PF07310.13 GBG66037.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.2 1 1 0 1 1 1 0 PAS domain Alpha-amylase PF00128.24 GBG66038.1 - 8.5e-23 81.4 0.0 3.8e-17 62.9 0.0 2.8 2 1 1 3 3 3 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 GBG66038.1 - 8.8e-08 31.6 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Bac_A_amyl_C PF18612.1 GBG66038.1 - 1.5e-05 24.7 0.0 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial Alpha amylase C-terminal domain GHL6 PF14871.6 GBG66038.1 - 7.6e-05 22.9 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 DUF4015 PF13200.6 GBG66038.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain PBP1_TM PF14812.6 GBG66039.1 - 0.015 15.7 1.8 0.019 15.3 1.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ParBc PF02195.18 GBG66039.1 - 0.018 15.3 0.2 0.024 14.9 0.2 1.2 1 0 0 1 1 1 0 ParB-like nuclease domain adh_short PF00106.25 GBG66040.1 - 1.2e-45 155.4 0.1 1.6e-45 155.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG66040.1 - 3e-27 95.7 0.1 4.1e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG66040.1 - 1.7e-12 47.6 0.6 4.5e-12 46.3 0.6 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GBG66040.1 - 0.014 14.9 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Apolipoprotein PF01442.18 GBG66041.1 - 9.1e-07 28.9 23.3 0.0013 18.6 5.9 3.0 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GBG66041.1 - 0.0022 18.5 31.1 0.45 11.2 5.2 4.8 1 1 3 5 5 5 5 Bacterial protein of unknown function (DUF883) PRKCSH-like PF12999.7 GBG66041.1 - 0.11 12.3 0.3 0.26 11.1 0.3 1.7 1 0 0 1 1 1 0 Glucosidase II beta subunit-like PseudoU_synth_1 PF01416.20 GBG66042.1 - 7e-28 97.2 0.0 1.8e-20 73.4 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase TFIIF_alpha PF05793.12 GBG66042.1 - 0.018 13.7 6.2 0.026 13.1 6.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.14 GBG66042.1 - 0.019 14.8 4.6 0.032 14.0 4.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2052 PF09747.9 GBG66042.1 - 0.032 14.4 10.4 0.052 13.7 10.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNA_pol_3_Rpc31 PF11705.8 GBG66042.1 - 0.036 14.3 12.9 0.071 13.4 12.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 GBG66042.1 - 0.15 12.0 2.5 0.26 11.2 2.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 GBG66042.1 - 0.49 9.7 9.4 0.78 9.0 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 GBG66042.1 - 0.67 9.9 6.9 1.1 9.1 6.9 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RXT2_N PF08595.11 GBG66042.1 - 0.67 10.0 5.9 1.2 9.2 5.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC27 PF09507.10 GBG66042.1 - 0.74 9.1 6.2 1.2 8.4 6.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Paf1 PF03985.13 GBG66042.1 - 0.79 8.7 13.8 1.2 8.1 13.8 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 GBG66042.1 - 1.1 7.4 11.9 1.4 7.0 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG66042.1 - 1.8 6.8 9.0 2.5 6.3 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 GBG66042.1 - 1.9 7.5 17.9 3.4 6.7 17.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 GBG66042.1 - 2.2 8.0 8.7 4.4 6.9 8.7 1.4 1 0 0 1 1 1 0 FAM176 family Pap_E4 PF02711.14 GBG66042.1 - 2.9 8.9 4.0 0.99 10.4 0.3 2.1 2 0 0 2 2 1 0 E4 protein DNA_pol_phi PF04931.13 GBG66042.1 - 6.9 4.6 17.4 9.3 4.2 17.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi RRS1 PF04939.12 GBG66043.1 - 0.021 14.7 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) JmjC PF02373.22 GBG66043.1 - 0.03 14.7 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase A1_Propeptide PF07966.12 GBG66043.1 - 0.34 10.8 2.2 0.8 9.6 2.2 1.6 1 0 0 1 1 1 0 A1 Propeptide ATG11 PF10377.9 GBG66044.1 - 4.8e-07 29.9 0.0 3.1e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.12 GBG66044.1 - 0.00083 18.6 33.4 0.00093 18.4 5.9 4.2 3 1 0 4 4 4 3 Autophagy protein Apg17 IKKbetaNEMObind PF12179.8 GBG66044.1 - 0.045 13.8 2.7 0.072 13.1 0.8 2.5 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain NPV_P10 PF05531.12 GBG66044.1 - 0.19 12.2 9.6 19 5.8 0.1 4.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1319 PF07028.11 GBG66044.1 - 1.6 9.0 8.9 1.2 9.4 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1319) ATG16 PF08614.11 GBG66044.1 - 2.7 8.2 32.2 0.23 11.7 9.4 4.5 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) MPS2 PF17060.5 GBG66044.1 - 5.1 6.2 9.0 0.32 10.2 0.4 2.8 3 0 0 3 3 3 0 Monopolar spindle protein 2 MATH PF00917.26 GBG66045.1 - 2.3e-17 63.2 0.0 6e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 MATH domain FAM76 PF16046.5 GBG66045.1 - 2 7.7 0.0 2 7.7 0.0 4.3 4 0 0 4 4 4 0 FAM76 protein MATH PF00917.26 GBG66046.1 - 2.3e-17 63.2 0.0 6e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 MATH domain DUF659 PF04937.15 GBG66047.1 - 9.1e-15 54.8 0.0 2.3e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG66047.1 - 6.3e-05 22.7 0.1 0.00014 21.5 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PyrI_C PF02748.15 GBG66047.1 - 0.064 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain RVT_1 PF00078.27 GBG66048.1 - 1.6e-36 125.9 0.1 3.4e-36 124.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66048.1 - 1.1e-29 102.8 0.2 4.6e-29 100.8 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66048.1 - 1.2e-29 102.3 0.0 1.3e-28 99.0 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Nucleopor_Nup85 PF07575.13 GBG66048.1 - 4.1e-17 62.0 0.1 2.1e-16 59.6 0.0 1.9 1 1 1 2 2 2 1 Nup85 Nucleoporin Phage_GPO PF05929.11 GBG66048.1 - 0.12 11.9 1.1 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Nucleopor_Nup85 PF07575.13 GBG66049.1 - 2.1e-20 72.9 0.1 3.1e-20 72.3 0.1 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin Integrase_H2C2 PF17921.1 GBG66049.1 - 3.1e-19 68.8 0.3 7.1e-19 67.7 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG66049.1 - 1e-09 38.3 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG66049.1 - 1.9e-09 37.7 0.0 8.4e-09 35.6 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG66049.1 - 5.7e-06 26.9 0.0 1.2e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG66049.1 - 7.3e-06 25.8 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG66049.1 - 0.0007 20.1 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG66049.1 - 0.0021 18.0 0.0 0.0074 16.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG66049.1 - 0.047 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG66049.1 - 0.093 13.0 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Abhydro_lipase PF04083.16 GBG66049.1 - 0.13 11.9 0.1 0.38 10.4 0.1 1.8 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF659 PF04937.15 GBG66050.1 - 3.4e-27 95.2 0.0 6.3e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG66050.1 - 0.098 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Nucleopor_Nup85 PF07575.13 GBG66051.1 - 1.2e-14 53.9 0.3 1.5e-14 53.5 0.3 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Trypsin PF00089.26 GBG66052.1 - 2.5e-30 105.9 0.0 6.3e-18 65.4 0.0 2.3 2 0 0 2 2 2 2 Trypsin GDPD PF03009.17 GBG66055.1 - 3e-45 155.0 0.0 3.8e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Tim17 PF02466.19 GBG66056.1 - 1.1e-12 48.3 0.4 8.8e-08 32.5 0.1 2.6 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 GBG66056.1 - 1.7e-05 25.4 2.2 0.00027 21.5 0.5 2.3 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 BRE1 PF08647.11 GBG66056.1 - 0.046 13.8 0.3 0.1 12.7 0.3 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Plavaka PF18759.1 GBG66057.1 - 3.2e-25 89.1 0.4 5.5e-25 88.3 0.4 1.3 1 0 0 1 1 1 1 Plavaka transposase BUD22 PF09073.10 GBG66057.1 - 1.7 7.9 17.2 3 7.1 17.2 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG66057.1 - 3.9 5.7 8.8 5.8 5.1 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG66060.1 - 0.0047 15.2 16.2 0.0048 15.2 16.2 1.1 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 GBG66060.1 - 0.013 15.6 17.1 0.015 15.4 17.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 GBG66060.1 - 0.013 13.8 13.1 0.015 13.6 13.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG66060.1 - 0.15 10.1 24.3 0.17 9.9 24.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 GBG66060.1 - 0.19 10.9 25.3 0.25 10.4 25.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 GBG66060.1 - 0.27 10.5 14.1 0.31 10.3 14.1 1.2 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 GBG66060.1 - 0.33 10.3 16.6 0.33 10.3 15.9 1.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 GBG66060.1 - 0.47 9.6 9.5 0.54 9.4 9.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.8 GBG66060.1 - 1.1 8.1 9.0 1.1 8.1 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PTPRCAP PF15713.5 GBG66060.1 - 1.4 9.2 14.6 1.9 8.7 14.6 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 GBG66060.1 - 2.3 6.9 3.5 2.3 6.9 3.5 1.1 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 GBG66060.1 - 2.6 5.0 8.4 2.9 4.9 8.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RRN3 PF05327.11 GBG66060.1 - 3.9 5.9 15.8 4.4 5.7 15.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 GBG66060.1 - 6.4 6.5 16.1 9.7 5.9 16.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4187 PF13821.6 GBG66061.1 - 0.0018 18.0 1.1 0.0018 18.0 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG66061.1 - 0.12 12.7 1.6 0.18 12.1 0.2 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein DUF5526 PF17664.1 GBG66063.1 - 0.11 12.0 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5526) Myb_DNA-bind_4 PF13837.6 GBG66063.1 - 0.26 11.7 3.7 0.64 10.4 3.7 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG66064.1 - 3.1e-06 27.5 0.8 5.6e-06 26.7 0.3 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG66064.1 - 0.0022 18.0 0.2 0.0044 17.1 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG66065.1 - 6.2e-18 65.0 0.0 8.4e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66065.1 - 0.00021 20.9 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein gag-asp_proteas PF13975.6 GBG66066.1 - 0.023 15.3 0.0 0.069 13.7 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66066.1 - 0.027 15.1 0.0 0.084 13.5 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG66066.1 - 0.14 11.8 0.2 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-C4pol PF14260.6 GBG66070.1 - 2.7 8.5 12.0 0.28 11.7 4.2 2.7 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-C2HC5 PF06221.13 GBG66072.1 - 0.091 12.8 0.4 0.18 11.8 0.4 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type LEA_2 PF03168.13 GBG66074.1 - 2.4e-24 85.8 0.1 2e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 Late embryogenesis abundant protein Flp1_like PF16982.5 GBG66074.1 - 1.3 8.4 5.5 0.52 9.8 2.0 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain DDE_Tnp_4 PF13359.6 GBG66076.1 - 2.8e-12 46.6 0.0 4.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66076.1 - 0.00012 21.8 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DUF5336 PF17270.2 GBG66077.1 - 0.13 11.9 0.0 3.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5336) HMW1C_N PF18071.1 GBG66077.1 - 0.74 9.6 2.2 0.78 9.5 0.6 1.9 2 0 0 2 2 2 0 HMW1C N-terminal eIF3_N PF09440.10 GBG66081.1 - 0.28 11.6 0.2 0.5 10.8 0.2 1.4 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain TetR_C_15 PF17918.1 GBG66084.1 - 0.011 16.5 1.8 0.08 13.7 0.0 3.1 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Dynein_heavy PF03028.15 GBG66084.1 - 0.39 10.8 1.1 0.63 10.1 0.1 1.8 2 0 0 2 2 2 0 Dynein heavy chain region D6 P-loop domain DUF659 PF04937.15 GBG66087.1 - 1.2e-18 67.4 0.0 2.5e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG66089.1 - 5e-19 68.7 0.0 1.1e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG66089.1 - 7e-08 32.2 1.0 3.2e-07 30.0 0.4 2.3 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region Lin-8 PF03353.15 GBG66089.1 - 0.21 11.1 5.2 0.4 10.2 5.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Myb_DNA-bind_4 PF13837.6 GBG66092.1 - 1.1e-06 28.9 3.2 2.2e-06 27.9 3.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG66092.1 - 0.046 14.1 1.7 0.083 13.2 1.7 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CBP_BcsR PF10945.8 GBG66092.1 - 0.046 13.2 0.5 0.11 11.9 0.5 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR Actin PF00022.19 GBG66092.1 - 0.067 11.8 0.1 0.098 11.2 0.1 1.1 1 0 0 1 1 1 0 Actin Sporozoite_P67 PF05642.11 GBG66092.1 - 7.2 4.6 12.0 9.9 4.1 12.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RVT_1 PF00078.27 GBG66093.1 - 4.2e-37 127.8 0.0 5.3e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TetR_C_15 PF17918.1 GBG66100.1 - 0.36 11.6 2.0 0.63 10.8 0.2 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Myb_DNA-bind_4 PF13837.6 GBG66101.1 - 0.0034 17.7 0.1 0.005 17.2 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Co_AT_N PF12557.8 GBG66102.1 - 0.016 15.1 4.7 0.016 15.1 4.7 2.4 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal DUF5486 PF17588.2 GBG66104.1 - 0.84 9.6 5.2 0.78 9.7 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5486) SlyX PF04102.12 GBG66106.1 - 2.2 9.0 15.1 4.4 8.0 0.1 6.7 5 1 0 5 5 5 0 SlyX Fib_alpha PF08702.10 GBG66107.1 - 0.49 10.6 10.7 0.76 10.0 2.8 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DNApol_Exo PF18136.1 GBG66107.1 - 0.84 8.7 5.4 1.4 8.0 5.4 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Presenilin PF01080.17 GBG66108.1 - 3.6 6.2 12.2 4 6.1 12.2 1.0 1 0 0 1 1 1 0 Presenilin Nop53 PF07767.11 GBG66108.1 - 3.8 6.8 34.4 4.5 6.5 34.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Vfa1 PF08432.10 GBG66108.1 - 4.1 7.7 15.5 5 7.4 15.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 GBG66108.1 - 7.2 4.8 24.1 8.2 4.6 24.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG66108.1 - 7.7 4.6 24.2 8 4.5 24.2 1.0 1 0 0 1 1 1 0 Nop14-like family eIF-3_zeta PF05091.12 GBG66108.1 - 8.1 5.3 11.2 9.1 5.1 11.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BORG_CEP PF14957.6 GBG66108.1 - 8.2 7.6 5.8 9.1 7.5 5.8 1.1 1 0 0 1 1 1 0 Cdc42 effector RR_TM4-6 PF06459.12 GBG66108.1 - 8.8 6.1 19.5 11 5.7 19.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG66108.1 - 9.2 5.6 29.2 11 5.4 29.2 1.0 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG66110.1 - 8.5e-27 94.1 0.0 2.4e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66110.1 - 4.9e-26 90.7 0.0 1.5e-25 89.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66110.1 - 2.1e-24 85.8 0.0 5.7e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66110.1 - 1.9e-18 66.3 0.5 5.7e-18 64.8 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG66110.1 - 1.3e-09 38.3 0.0 4.9e-09 36.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG66110.1 - 1.3e-07 32.2 0.0 3.8e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66110.1 - 8.9e-07 29.4 0.0 2.6e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG66110.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66110.1 - 4.7e-05 23.2 0.0 8.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG66110.1 - 0.00046 20.4 0.1 0.0032 17.7 0.1 2.5 1 0 0 1 1 1 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG66110.1 - 0.029 14.8 0.9 1.7 9.2 0.1 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nudix_N_2 PF14803.6 GBG66112.1 - 3.2 7.8 5.1 6.8 6.7 0.7 2.6 2 0 0 2 2 2 0 Nudix N-terminal RVT_1 PF00078.27 GBG66113.1 - 4.3e-46 157.2 0.5 1.7e-23 83.3 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66113.1 - 7.8e-09 35.5 0.0 3.5e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG66113.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Chromo PF00385.24 GBG66113.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF4399 PF14347.6 GBG66113.1 - 0.17 12.2 0.0 6.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) RT_RNaseH_2 PF17919.1 GBG66114.1 - 4e-15 55.7 0.0 7.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66114.1 - 1.7e-09 37.5 0.5 2.7e-09 36.9 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66114.1 - 6.5e-07 29.6 0.0 1.3e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG66119.1 - 5.6e-06 26.2 2.1 1.2e-05 25.1 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG66119.1 - 0.00049 19.9 2.3 0.001 18.8 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG66119.1 - 0.026 14.5 0.2 0.066 13.2 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Tfb4 PF03850.14 GBG66119.1 - 0.23 10.9 2.8 0.37 10.2 2.8 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 ArAE_2_N PF10337.9 GBG66119.1 - 2.6 7.0 4.7 3.6 6.5 4.7 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF4407 PF14362.6 GBG66119.1 - 6.5 6.0 10.1 9.8 5.4 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF572 PF04502.13 GBG66120.1 - 0.11 12.1 15.6 0.14 11.7 15.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GUN4 PF05419.12 GBG66123.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 GUN4-like zf-CCHC PF00098.23 GBG66125.1 - 1.4 9.1 4.4 2.4 8.4 2.8 2.1 2 0 0 2 2 2 0 Zinc knuckle Pkinase_Tyr PF07714.17 GBG66126.1 - 2.5e-68 230.2 0.0 6e-68 228.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG66126.1 - 1.8e-55 188.1 0.0 3e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EDR1 PF14381.6 GBG66126.1 - 2.5e-39 135.1 0.0 4e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 PAS PF00989.25 GBG66126.1 - 1.1e-12 48.0 0.0 2.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GBG66126.1 - 1.2e-08 35.1 0.0 3.4e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 GBG66126.1 - 8.5e-07 29.2 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 GBG66126.1 - 1.3e-06 28.6 0.0 3.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 GBG66126.1 - 0.00011 22.1 0.0 0.00033 20.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 GBG66126.1 - 0.013 14.5 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 GBG66126.1 - 0.024 14.6 0.1 0.18 11.7 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DDE_Tnp_4 PF13359.6 GBG66129.1 - 6e-13 48.8 0.0 1.3e-12 47.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66129.1 - 4.2e-06 26.5 0.0 6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Wtap PF17098.5 GBG66130.1 - 0.067 13.1 0.2 0.38 10.7 0.1 2.0 2 0 0 2 2 2 0 WTAP/Mum2p family SlyX PF04102.12 GBG66130.1 - 0.27 11.9 3.4 3.2 8.4 0.4 2.6 2 1 0 2 2 2 0 SlyX FlxA PF14282.6 GBG66130.1 - 3 7.9 8.7 1.8 8.6 1.0 2.3 2 1 0 2 2 2 0 FlxA-like protein bZIP_1 PF00170.21 GBG66131.1 - 3e-11 43.2 6.9 5.3e-11 42.5 6.4 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG66131.1 - 3.4e-06 27.0 7.8 6.6e-06 26.1 7.0 1.8 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_C PF12498.8 GBG66131.1 - 8.1e-05 23.6 0.3 0.00068 20.6 0.0 2.3 2 1 1 3 3 3 1 Basic leucine-zipper C terminal DUF2353 PF09789.9 GBG66131.1 - 0.016 14.6 0.5 0.02 14.2 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TMCO5 PF14992.6 GBG66131.1 - 0.088 12.4 0.2 0.11 12.0 0.2 1.1 1 0 0 1 1 1 0 TMCO5 family Fer2_BFD PF04324.15 GBG66131.1 - 0.16 12.3 0.0 0.52 10.7 0.0 1.8 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain HAUS-augmin3 PF14932.6 GBG66131.1 - 0.16 11.5 0.8 0.23 11.0 0.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DDE_Tnp_4 PF13359.6 GBG66132.1 - 7.3e-23 81.0 0.0 1.3e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66132.1 - 4.6e-12 46.0 0.0 1e-10 41.6 0.0 2.5 2 1 1 3 3 3 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66132.1 - 0.028 14.0 0.1 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 Transposase DDE domain RVT_1 PF00078.27 GBG66134.1 - 5.5e-31 107.8 0.0 9.5e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66134.1 - 5.9e-16 58.3 0.1 1.5e-15 57.0 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66134.1 - 1e-14 54.8 0.1 2.8e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG66135.1 - 1.3e-29 102.5 0.0 2.5e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66135.1 - 3.5e-29 100.8 0.0 6.6e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66136.1 - 1.1e-29 103.6 0.1 1.6e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) REV PF00424.18 GBG66136.1 - 0.9 9.6 5.5 0.43 10.6 0.6 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Herpes_UL25 PF01499.16 GBG66136.1 - 6.4 5.2 7.3 5.3 5.5 5.7 1.6 2 0 0 2 2 2 0 Herpesvirus UL25 family Sporozoite_P67 PF05642.11 GBG66137.1 - 0.0094 14.1 2.6 0.012 13.7 2.6 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Spt20 PF12090.8 GBG66137.1 - 0.18 11.4 3.2 0.25 10.9 3.2 1.1 1 0 0 1 1 1 0 Spt20 family RXT2_N PF08595.11 GBG66137.1 - 0.26 11.3 3.1 0.17 11.9 1.2 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal LEA_2 PF03168.13 GBG66137.1 - 0.73 10.4 8.5 68 4.1 0.0 2.8 2 1 1 3 3 3 0 Late embryogenesis abundant protein RVT_1 PF00078.27 GBG66138.1 - 5.2e-27 94.8 0.1 7.6e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66138.1 - 1.9e-26 92.0 0.0 4.5e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66138.1 - 1e-21 77.2 0.0 2.6e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG66138.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease ST7 PF04184.12 GBG66138.1 - 0.052 12.0 0.1 0.077 11.5 0.1 1.1 1 0 0 1 1 1 0 ST7 protein RT_RNaseH PF17917.1 GBG66140.1 - 3.8e-32 110.7 0.0 6.4e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66140.1 - 7.5e-27 93.3 0.0 1.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG66140.1 - 1.8e-08 34.1 1.2 3.4e-08 33.2 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG66140.1 - 7.4e-05 22.5 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG66140.1 - 0.00064 20.2 0.0 0.025 15.1 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG66140.1 - 0.02 14.7 2.7 0.036 13.9 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Peptidase_C21 PF05381.12 GBG66141.1 - 0.003 17.9 0.1 0.0056 17.0 0.1 1.4 1 0 0 1 1 1 1 Tymovirus endopeptidase DDE_Tnp_4 PF13359.6 GBG66142.1 - 9.5e-26 90.3 0.0 1.5e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66142.1 - 2e-14 53.7 0.0 2.9e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66142.1 - 9.6e-05 22.1 0.1 0.25 11.0 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain WIYLD PF10440.9 GBG66142.1 - 0.084 12.7 0.2 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain NPR3 PF03666.13 GBG66144.1 - 2.2 7.0 8.3 3.2 6.5 8.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 V_ATPase_I PF01496.19 GBG66144.1 - 2.7 5.8 5.6 3.6 5.4 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 GBG66144.1 - 2.8 6.6 5.0 3.7 6.2 5.0 1.1 1 0 0 1 1 1 0 Presenilin DUF493 PF04359.14 GBG66145.1 - 1e-15 58.0 0.0 1.8e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF493) RT_RNaseH_2 PF17919.1 GBG66147.1 - 8.3e-28 96.4 0.0 2e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66147.1 - 6.9e-24 84.1 0.0 1.7e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66147.1 - 8e-20 71.3 0.0 1.5e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG66147.1 - 2.6e-10 40.5 0.0 9.9e-10 38.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG66147.1 - 0.00084 19.2 0.1 0.003 17.4 0.0 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG66147.1 - 0.0076 16.5 0.9 0.54 10.6 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein Ribosomal_S19 PF00203.21 GBG66149.1 - 0.046 13.6 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S19 Myb_DNA-binding PF00249.31 GBG66150.1 - 2.7e-08 33.9 0.0 6.5e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Response_reg PF00072.24 GBG66150.1 - 4.5e-07 30.0 0.0 0.00036 20.7 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain FAM176 PF14851.6 GBG66150.1 - 0.68 9.6 9.2 0.2 11.3 0.5 2.4 2 0 0 2 2 2 0 FAM176 family UPF0242 PF06785.11 GBG66152.1 - 0.45 10.6 11.1 1.1 9.4 11.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 GBG66152.1 - 3.3 8.2 9.9 10 6.6 9.0 2.0 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.19 GBG66153.1 - 0.69 7.8 9.5 0.82 7.5 9.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4207 PF13904.6 GBG66153.1 - 2.3 7.8 22.3 0.07 12.8 15.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4207) DUF724 PF05266.14 GBG66154.1 - 4.5 7.1 19.8 0.078 12.8 10.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Glyco_hydro_129 PF11308.8 GBG66155.1 - 0.015 14.5 0.9 0.063 12.4 0.1 1.9 1 1 0 2 2 2 0 Glycosyl hydrolases related to GH101 family, GH129 FlxA PF14282.6 GBG66155.1 - 0.021 14.8 0.6 0.021 14.8 0.6 3.1 2 1 0 3 3 3 0 FlxA-like protein SlyX PF04102.12 GBG66155.1 - 0.022 15.4 13.8 3 8.5 1.3 3.9 4 1 0 4 4 4 0 SlyX Retrotrans_gag PF03732.17 GBG66155.1 - 0.11 12.8 6.4 1 9.7 0.0 3.4 3 1 0 3 3 3 0 Retrotransposon gag protein CLZ PF16526.5 GBG66155.1 - 0.17 12.2 2.4 0.99 9.8 0.1 3.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mu-like_Pro PF10123.9 GBG66155.1 - 0.42 10.1 12.7 0.21 11.1 10.6 1.5 2 0 0 2 2 2 0 Mu-like prophage I protein DivIC PF04977.15 GBG66155.1 - 0.6 9.9 6.1 4.9 7.0 0.1 3.0 3 0 0 3 3 3 0 Septum formation initiator RVT_1 PF00078.27 GBG66156.1 - 4.5e-32 111.4 0.0 7.1e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66156.1 - 3.5e-31 107.2 0.0 1e-16 60.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66156.1 - 4.4e-26 91.2 0.0 8.8e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2385 PF09539.10 GBG66157.1 - 0.016 15.8 0.1 0.48 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) zf-CCHC PF00098.23 GBG66157.1 - 0.063 13.4 0.8 0.11 12.7 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG66157.1 - 0.27 11.1 4.2 0.42 10.5 4.2 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG66158.1 - 5.1e-30 103.5 0.0 1e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66158.1 - 6.3e-29 101.1 0.2 1.2e-28 100.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66158.1 - 1.1e-26 93.2 0.2 2.3e-26 92.1 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66158.1 - 1.4e-20 73.1 0.1 4.2e-20 71.6 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66158.1 - 5.8e-16 58.8 0.0 1.4e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG66158.1 - 0.00014 22.0 0.0 0.00052 20.2 0.0 2.0 2 0 0 2 2 2 1 H2C2 zinc finger Choline_kinase PF01633.20 GBG66159.1 - 2.8e-60 203.6 0.0 3.8e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GBG66159.1 - 1.5e-10 41.4 0.8 4.6e-10 39.8 0.8 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG66159.1 - 0.16 10.8 0.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain PRIMA1 PF16101.5 GBG66159.1 - 0.2 11.7 20.9 1.9 8.6 2.6 3.6 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DUF4106 PF13388.6 GBG66159.1 - 0.4 9.9 3.7 0.65 9.2 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) AP1AR PF15745.5 GBG66160.1 - 1.8 8.1 16.0 0.87 9.2 13.3 1.7 1 1 0 2 2 2 0 AP-1 complex-associated regulatory protein Paz_1 PF18349.1 GBG66160.1 - 3.9 7.5 5.8 95 3.1 0.0 2.3 2 0 0 2 2 2 0 PAZ domain Kinesin_assoc PF16183.5 GBG66160.1 - 7.1 6.7 13.4 24 5.0 0.2 2.6 1 1 1 2 2 2 0 Kinesin-associated DUF3535 PF12054.8 GBG66161.1 - 8e-84 282.4 0.0 7.6e-82 275.9 0.0 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 GBG66161.1 - 1.1e-63 215.1 0.0 2.1e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.22 GBG66161.1 - 5.4e-18 63.5 30.6 0.0097 16.1 0.1 11.3 11 0 0 11 11 11 4 HEAT repeat Helicase_C PF00271.31 GBG66161.1 - 5.2e-15 55.8 0.0 1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.6 GBG66161.1 - 9.2e-11 42.0 21.2 0.00041 20.7 1.5 7.0 7 1 1 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 GBG66161.1 - 2.1e-06 28.1 30.5 3.8e-05 24.1 0.8 8.7 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GBG66161.1 - 0.00012 22.6 0.0 0.015 15.9 0.0 3.1 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 GBG66161.1 - 0.0071 16.6 0.2 1 9.7 0.1 3.8 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain DUF3385 PF11865.8 GBG66161.1 - 0.013 15.4 0.1 0.14 12.1 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 GBG66161.1 - 0.019 13.6 1.2 3 6.3 0.1 3.6 4 0 0 4 4 4 0 Adaptin N terminal region Cnd1 PF12717.7 GBG66161.1 - 0.021 14.9 0.9 6.8 6.7 0.1 3.8 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RVT_1 PF00078.27 GBG66163.1 - 3.4e-52 177.2 0.2 4e-27 95.2 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66163.1 - 4e-35 119.9 1.1 2e-32 111.2 0.0 3.0 3 0 0 3 3 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66163.1 - 5.7e-29 100.5 0.0 1.8e-28 98.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66163.1 - 6.5e-18 64.6 0.2 1.5e-17 63.5 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1664 PF07889.12 GBG66163.1 - 0.001 19.1 1.0 0.0031 17.5 1.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 GBG66163.1 - 0.0061 16.6 2.1 0.0061 16.6 2.1 1.9 2 0 0 2 2 2 1 TolA binding protein trimerisation CDC27 PF09507.10 GBG66163.1 - 0.022 14.2 31.1 0.041 13.3 31.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NPR3 PF03666.13 GBG66163.1 - 0.11 11.3 24.3 0.18 10.6 24.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HalX PF08663.10 GBG66163.1 - 0.2 12.0 2.2 29 5.1 0.0 3.8 3 0 0 3 3 3 0 HalX domain DUF5427 PF10310.9 GBG66163.1 - 0.37 9.7 16.8 0.61 9.0 16.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RR_TM4-6 PF06459.12 GBG66163.1 - 8.7 6.1 28.3 17 5.1 28.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 GBG66163.1 - 9.1 6.2 8.7 12 5.8 6.7 2.3 2 0 0 2 2 2 0 N-glycosylation protein AAA_11 PF13086.6 GBG66163.1 - 9.7 5.9 20.2 27 4.4 20.2 1.7 1 0 0 1 1 1 0 AAA domain EFG_IV PF03764.18 GBG66165.1 - 2.7e-29 101.4 0.0 5.9e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 GBG66165.1 - 2.6e-18 65.8 0.0 8e-18 64.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 GBG66165.1 - 6.2e-11 42.2 0.0 1.4e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 GBG66165.1 - 0.0087 16.4 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RVT_1 PF00078.27 GBG66166.1 - 3.8e-16 59.3 0.2 6.8e-16 58.5 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_34 PF05637.12 GBG66168.1 - 4.4e-25 88.8 0.2 1.6e-24 87.0 0.2 1.8 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF3138 PF11336.8 GBG66169.1 - 0.062 11.9 1.9 0.087 11.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2950 PF11453.8 GBG66169.1 - 0.22 10.7 9.5 0.24 10.6 8.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2950) Uso1_p115_C PF04871.13 GBG66169.1 - 1.1 9.7 35.6 1.5 9.2 10.2 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Paf1 PF03985.13 GBG66170.1 - 1.4 7.8 29.2 2.4 7.1 29.2 1.4 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.14 GBG66170.1 - 3 7.6 22.4 6.1 6.6 22.4 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM60A PF15396.6 GBG66170.1 - 3.4 7.6 9.2 5.5 6.9 9.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A NPR3 PF03666.13 GBG66170.1 - 7 5.3 15.0 11 4.6 15.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 GBG66170.1 - 7.4 6.3 18.0 13 5.5 18.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2537 PF10801.8 GBG66171.1 - 0.04 14.1 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) DUF659 PF04937.15 GBG66172.1 - 1.1e-24 87.0 0.0 2.7e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG66172.1 - 1.6e-06 27.8 0.0 3.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ribosomal_L4 PF00573.22 GBG66173.1 - 2.4 7.8 5.8 3.2 7.4 5.8 1.1 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family DUF5525 PF17663.1 GBG66176.1 - 0.0022 16.2 2.3 0.003 15.7 2.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5525) MSP1_C PF07462.11 GBG66176.1 - 0.008 14.9 1.1 0.008 14.9 1.1 1.6 2 0 0 2 2 2 1 Merozoite surface protein 1 (MSP1) C-terminus FSA_C PF10479.9 GBG66176.1 - 0.14 10.3 2.0 0.19 9.8 2.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RVT_1 PF00078.27 GBG66178.1 - 4e-20 72.3 0.0 7.6e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG66179.1 - 9.2e-30 103.8 0.0 1.3e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66179.1 - 4.2e-10 39.6 0.0 9.4e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG66179.1 - 8.5e-09 35.3 0.0 1.9e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG66179.1 - 7.2e-08 33.0 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66179.1 - 8.9e-07 29.4 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG66179.1 - 0.0029 17.9 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG66179.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease APG17 PF04108.12 GBG66179.1 - 0.065 12.3 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DNA_mis_repair PF01119.19 GBG66180.1 - 0.0071 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Ribosomal_60s PF00428.19 GBG66180.1 - 1.5 9.4 6.5 9.4 6.9 6.5 2.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myb_DNA-bind_4 PF13837.6 GBG66181.1 - 2.1e-05 24.8 0.9 4.6e-05 23.7 0.9 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG66181.1 - 0.00021 21.3 1.2 0.00021 21.3 1.2 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain TMIE PF16038.5 GBG66181.1 - 0.11 12.3 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 TMIE protein EphA2_TM PF14575.6 GBG66181.1 - 0.15 12.9 0.0 2 9.4 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DDE_Tnp_4 PF13359.6 GBG66185.1 - 2.9e-24 85.5 0.0 5.6e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66185.1 - 4.7e-10 39.4 0.0 7.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein PRONE PF03759.13 GBG66186.1 - 5.3e-172 571.7 0.3 7.1e-128 426.5 0.1 3.9 1 1 1 2 2 2 2 PRONE (Plant-specific Rop nucleotide exchanger) PRONE PF03759.13 GBG66187.1 - 1.7e-148 494.3 0.1 2e-147 490.8 0.1 2.1 1 1 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) PRONE PF03759.13 GBG66188.1 - 1.7e-148 494.3 0.1 2e-147 490.8 0.1 2.1 1 1 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) RT_RNaseH_2 PF17919.1 GBG66189.1 - 1.6e-20 73.0 0.0 4.9e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66189.1 - 7.6e-10 39.0 0.1 4e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase LPP20 PF02169.16 GBG66189.1 - 0.59 10.5 14.7 6.6 7.2 9.5 2.5 1 1 1 2 2 2 0 LPP20 lipoprotein DUF1993 PF09351.10 GBG66189.1 - 4.7 7.3 7.7 8.4 6.5 5.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Wtap PF17098.5 GBG66190.1 - 6.5e-38 130.1 15.1 1.4e-37 129.0 12.2 2.3 2 0 0 2 2 2 1 WTAP/Mum2p family HEPN_SAV_6107 PF18726.1 GBG66190.1 - 0.041 14.4 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 SAV_6107-like HEPN HIP1_clath_bdg PF16515.5 GBG66190.1 - 0.23 12.1 26.0 1.1 9.9 5.0 3.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 GBG66190.1 - 0.28 11.4 23.8 1.1 9.5 0.1 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Csm2_III-A PF03750.13 GBG66190.1 - 0.5 11.2 4.6 0.74 10.7 0.8 2.5 1 1 1 2 2 2 0 Csm2 Type III-A Spc29 PF17082.5 GBG66190.1 - 0.61 9.9 8.1 6.8 6.5 1.0 3.0 2 1 1 3 3 3 0 Spindle Pole Component 29 Glypican PF01153.19 GBG66190.1 - 1.2 7.9 5.7 0.52 9.1 2.7 2.0 2 0 0 2 2 2 0 Glypican DUF4140 PF13600.6 GBG66190.1 - 1.6 9.2 15.3 13 6.3 0.2 4.1 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) YbaB_DNA_bd PF02575.16 GBG66190.1 - 3.4 8.0 16.0 0.86 9.9 0.6 3.6 4 0 0 4 4 3 0 YbaB/EbfC DNA-binding family Nnf1 PF03980.14 GBG66190.1 - 5.1 7.5 15.2 5.2 7.5 3.8 3.3 3 1 0 3 3 3 0 Nnf1 FliJ PF02050.16 GBG66190.1 - 5.7 7.2 22.4 4.3 7.6 3.5 4.1 4 0 0 4 4 4 0 Flagellar FliJ protein DUF2120 PF09893.9 GBG66190.1 - 8.4 6.5 8.8 1.6 8.8 1.1 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Uso1_p115_head PF04869.14 GBG66191.1 - 1.5e-16 60.4 0.0 8.5e-13 48.1 0.0 3.9 3 1 0 3 3 3 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 GBG66191.1 - 4.3e-12 46.5 31.9 1.2e-09 38.6 19.0 3.6 2 1 1 3 3 3 2 Uso1 / p115 like vesicle tethering protein, C terminal region Arm PF00514.23 GBG66191.1 - 0.0033 17.4 0.9 0.15 12.2 0.0 4.0 3 1 1 4 4 4 1 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 GBG66191.1 - 0.015 14.9 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Tti2 family BLOC1_2 PF10046.9 GBG66191.1 - 0.023 15.0 0.1 0.057 13.7 0.1 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HEAT PF02985.22 GBG66191.1 - 0.62 10.5 3.3 27 5.4 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat Peptidase_M32 PF02074.15 GBG66191.1 - 2.1 7.0 5.4 3 6.5 5.4 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase SAM_Exu PF18609.1 GBG66191.1 - 2.1 8.5 4.4 1.4 9.0 0.1 2.9 3 1 0 3 3 3 0 Exuperantia SAM-like domain RVT_1 PF00078.27 GBG66192.1 - 2.2e-16 60.0 0.0 3.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG66192.1 - 0.0037 17.9 1.2 0.0037 17.9 1.2 2.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase MutS_V PF00488.21 GBG66194.1 - 4.1e-11 43.3 0.0 4.3e-09 36.7 0.0 2.9 3 0 0 3 3 3 1 MutS domain V HsbA PF12296.8 GBG66194.1 - 0.022 15.2 0.0 0.059 13.8 0.0 1.7 1 0 0 1 1 1 0 Hydrophobic surface binding protein A HD_5 PF13487.6 GBG66194.1 - 0.079 13.2 0.6 0.24 11.7 0.6 1.8 1 0 0 1 1 1 0 HD domain ATPase_2 PF01637.18 GBG66194.1 - 0.14 12.1 0.1 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 GBG66194.1 - 0.39 11.2 4.5 1.9 8.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Rhomboid PF01694.22 GBG66195.1 - 1.1e-35 122.9 16.7 2.1e-35 122.0 16.7 1.5 1 0 0 1 1 1 1 Rhomboid family Glyco_hydro_45 PF02015.16 GBG66195.1 - 0.0067 16.4 0.3 0.013 15.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Rhomboid PF01694.22 GBG66197.1 - 4.4e-37 127.4 15.1 8.8e-37 126.4 15.1 1.5 1 0 0 1 1 1 1 Rhomboid family zf-CCCH_6 PF18585.1 GBG66198.1 - 4.3 7.3 7.5 7.6 6.5 0.5 3.1 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Pkinase PF00069.25 GBG66199.1 - 6e-72 242.2 0.0 8.1e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG66199.1 - 5.1e-33 114.4 0.0 7.3e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG66199.1 - 1.2e-07 31.4 0.0 3.2e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 GBG66199.1 - 4.5e-07 30.5 0.5 1.1e-06 29.2 0.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 GBG66199.1 - 6.6e-05 22.0 0.0 9.6e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GBG66199.1 - 0.00025 21.1 0.2 0.11 12.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GBG66199.1 - 0.00087 18.7 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GBG66199.1 - 0.0038 16.9 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 GBG66199.1 - 0.027 13.3 0.0 0.057 12.2 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Nefa_Nip30_N PF10187.9 GBG66200.1 - 1.2e-11 44.8 8.6 1.2e-11 44.8 8.6 2.2 3 0 0 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Utp12 PF04003.12 GBG66201.1 - 1.4e-14 54.2 1.8 2.2e-14 53.6 1.8 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 GBG66201.1 - 1.4e-10 41.6 2.7 0.0099 16.7 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG66201.1 - 3.9e-08 33.5 0.0 0.0003 21.0 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GBG66201.1 - 9e-07 28.7 0.5 6.2e-06 26.0 0.3 2.5 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 GBG66201.1 - 0.00094 19.0 0.0 0.33 11.0 0.0 3.3 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 GBG66201.1 - 0.0011 19.3 7.0 0.0024 18.3 0.2 4.1 5 0 0 5 5 5 1 PQQ-like domain Hira PF07569.11 GBG66201.1 - 0.0098 15.6 0.0 3.1 7.5 0.0 3.1 3 0 0 3 3 3 1 TUP1-like enhancer of split Acetyltransf_1 PF00583.25 GBG66202.1 - 0.00077 19.7 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Integrase_H2C2 PF17921.1 GBG66204.1 - 4.1e-18 65.2 0.3 1e-17 64.0 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG66204.1 - 9e-17 61.3 0.0 2.1e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG66204.1 - 1.5e-14 54.2 2.5 1.9e-14 53.9 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain UBA PF00627.31 GBG66204.1 - 1.8e-13 50.1 0.9 1.6e-05 24.7 0.1 3.8 3 0 0 3 3 3 3 UBA/TS-N domain RT_RNaseH_2 PF17919.1 GBG66204.1 - 1.8e-11 44.0 0.0 5e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG66204.1 - 0.00033 20.9 5.8 0.0014 18.8 0.1 4.1 4 0 0 4 4 4 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG66204.1 - 0.071 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger HemY_N PF07219.13 GBG66204.1 - 0.7 10.1 0.0 0.7 10.1 0.0 3.3 3 0 0 3 3 3 0 HemY protein N-terminus HOIP-UBA PF16678.5 GBG66204.1 - 4.5 7.3 18.3 0.065 13.2 0.4 3.8 4 1 1 5 5 5 0 HOIP UBA domain pair rve PF00665.26 GBG66205.1 - 1.9e-16 60.3 0.0 3.8e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain FtsK_4TM PF13491.6 GBG66205.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE rve_3 PF13683.6 GBG66205.1 - 0.16 11.8 0.7 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain DBD_Tnp_Mut PF03108.15 GBG66206.1 - 5.9e-15 55.0 0.5 9.9e-15 54.3 0.5 1.3 1 0 0 1 1 1 1 MuDR family transposase MULE PF10551.9 GBG66206.1 - 3.2e-09 37.1 0.0 5.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain CUE PF02845.16 GBG66207.1 - 0.0008 19.1 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 CUE domain DBD_Tnp_Hermes PF10683.9 GBG66208.1 - 0.025 14.2 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain S1-P1_nuclease PF02265.16 GBG66208.1 - 0.059 13.2 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 S1/P1 Nuclease GIY-YIG PF01541.24 GBG66210.1 - 0.54 10.6 0.0 0.54 10.6 0.0 2.7 3 0 0 3 3 3 0 GIY-YIG catalytic domain DNA_pack_N PF02500.15 GBG66210.1 - 2.5 7.9 5.5 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus RT_RNaseH PF17917.1 GBG66211.1 - 9.1e-22 77.3 0.0 1.6e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66211.1 - 1.4e-20 73.2 0.0 2.9e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66211.1 - 5.1e-20 72.0 0.2 1.1e-19 70.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG66211.1 - 0.0018 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease TetR_C_13 PF16925.5 GBG66212.1 - 0.32 10.9 6.9 0.74 9.8 0.3 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain eIF3_subunit PF08597.10 GBG66212.1 - 0.45 10.4 23.2 0.49 10.3 5.5 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit GOLD_2 PF13897.6 GBG66212.1 - 0.53 10.8 6.6 6.1 7.3 0.8 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking XFP_C PF09363.10 GBG66212.1 - 1.3 8.5 7.0 3.5 7.0 0.6 2.3 2 0 0 2 2 2 0 XFP C-terminal domain DUF3682 PF12446.8 GBG66212.1 - 2.5 8.6 12.2 3.1 8.3 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) ARGLU PF15346.6 GBG66212.1 - 2.7 7.9 26.6 6.3 6.7 8.6 2.5 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 GNAT_acetyltr_2 PF13718.6 GBG66212.1 - 9.5 5.5 9.1 13 5.1 1.5 2.2 2 0 0 2 2 2 0 GNAT acetyltransferase 2 RabGAP-TBC PF00566.18 GBG66213.1 - 3.1e-10 40.1 0.4 6.3e-10 39.1 0.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF563 PF04577.14 GBG66218.1 - 0.00014 22.1 0.0 0.00014 22.1 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF563) Apt1 PF10351.9 GBG66218.1 - 0.71 8.7 14.1 0.8 8.5 0.6 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Dynein_C PF18199.1 GBG66219.1 - 1.1e-67 228.4 1.0 1.6e-67 228.0 0.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 GBG66219.1 - 1.2e-54 184.5 0.0 2.1e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GBG66219.1 - 9.7e-43 145.1 0.0 1.1e-41 141.6 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 GBG66219.1 - 2.4e-40 138.0 2.4 8.3e-40 136.2 1.7 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region MAT1 PF06391.13 GBG66219.1 - 0.074 12.9 1.3 0.13 12.1 1.3 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF1043 PF06295.12 GBG66219.1 - 0.88 9.6 4.9 0.65 10.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Sec2p PF06428.11 GBG66219.1 - 9.2 6.3 15.2 1.1 9.2 3.7 3.3 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p DUF4360 PF14273.6 GBG66220.1 - 4.3e-31 108.1 0.0 6.5e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) AAA_6 PF12774.7 GBG66221.1 - 2.4e-159 529.6 0.0 1.7e-158 526.8 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 GBG66221.1 - 3.8e-100 334.5 0.0 9.9e-100 333.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 GBG66221.1 - 1.1e-74 249.8 3.0 7.6e-68 227.6 0.0 4.0 4 0 0 4 4 4 3 P-loop containing dynein motor region MT PF12777.7 GBG66221.1 - 7.4e-66 222.5 9.2 7.4e-66 222.5 9.2 1.9 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 GBG66221.1 - 7.7e-38 129.8 0.0 7.7e-38 129.8 0.0 3.9 4 0 0 4 4 2 1 ATP-binding dynein motor region DHC_N2 PF08393.13 GBG66221.1 - 6.2e-35 121.1 1.0 1.1e-33 117.0 0.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 RT_RNaseH_2 PF17919.1 GBG66221.1 - 3.4e-29 100.8 0.0 8.3e-29 99.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66221.1 - 2.1e-28 98.7 0.0 5.9e-28 97.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Dynein_AAA_lid PF17852.1 GBG66221.1 - 6.4e-26 90.9 0.0 2.1e-25 89.3 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 GBG66221.1 - 3.3e-24 85.5 0.3 4.9e-07 29.8 0.0 5.5 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 GBG66221.1 - 6.8e-15 55.1 0.0 2.7e-14 53.2 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain RVT_1 PF00078.27 GBG66221.1 - 2.3e-13 50.2 2.0 1.6e-08 34.4 0.0 3.6 4 1 1 5 5 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_22 PF13401.6 GBG66221.1 - 4.1e-10 40.1 0.5 0.021 15.1 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 GBG66221.1 - 2e-08 34.7 0.0 0.28 11.6 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG66221.1 - 6.9e-08 33.1 13.2 0.16 12.3 0.0 6.4 6 1 1 7 7 5 2 AAA ATPase domain Asp_protease_2 PF13650.6 GBG66221.1 - 2.6e-06 28.0 0.0 8.5e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease AAA_18 PF13238.6 GBG66221.1 - 5e-06 27.1 6.2 0.049 14.2 0.0 4.6 4 0 0 4 4 3 2 AAA domain RVP_2 PF08284.11 GBG66221.1 - 5.9e-06 26.1 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RsgA_GTPase PF03193.16 GBG66221.1 - 4e-05 23.6 0.3 0.0049 16.8 0.0 3.3 3 0 0 3 3 2 1 RsgA GTPase gag-asp_proteas PF13975.6 GBG66221.1 - 5.1e-05 23.7 0.5 0.00023 21.6 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Sigma54_activat PF00158.26 GBG66221.1 - 7.1e-05 22.6 0.2 1.4 8.6 0.0 3.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_29 PF13555.6 GBG66221.1 - 0.0022 17.7 0.2 4 7.3 0.1 3.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF1758 PF05585.12 GBG66221.1 - 0.0064 16.3 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Putative peptidase (DUF1758) PhoH PF02562.16 GBG66221.1 - 0.014 14.9 3.0 0.04 13.4 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein RNA_helicase PF00910.22 GBG66221.1 - 0.015 15.7 0.1 24 5.4 0.0 4.1 4 0 0 4 4 4 0 RNA helicase RRM_Rrp7 PF17799.1 GBG66221.1 - 0.034 14.0 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain ATP-synt_ab PF00006.25 GBG66221.1 - 0.1 12.2 0.0 11 5.5 0.0 3.3 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 GBG66221.1 - 0.53 10.6 3.9 82 3.5 0.1 4.3 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 GBG66221.1 - 0.71 9.2 3.7 0.98 8.7 0.0 3.1 4 0 0 4 4 3 0 FtsK/SpoIIIE family DUF853 PF05872.12 GBG66221.1 - 0.89 8.1 19.3 0.075 11.6 0.4 4.1 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF853) DUF4407 PF14362.6 GBG66221.1 - 2.9 7.2 38.1 0.075 12.4 1.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF659 PF04937.15 GBG66222.1 - 1.5e-37 128.8 0.0 3.3e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Glyco_hydro_9 PF00759.19 GBG66222.1 - 6.2 6.1 11.7 2.7 7.3 8.8 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 DHC_N2 PF08393.13 GBG66223.1 - 1.2e-84 284.7 11.4 2.1e-84 283.9 11.4 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Integrase_H2C2 PF17921.1 GBG66224.1 - 2.4e-13 50.0 0.0 5.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66224.1 - 1.3e-12 48.0 0.0 2.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG66224.1 - 0.0028 18.2 0.0 0.0063 17.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66224.1 - 0.0046 17.6 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG66224.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease rve_3 PF13683.6 GBG66224.1 - 0.03 14.1 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Asp_protease PF09668.10 GBG66224.1 - 0.081 12.7 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Aspartyl protease DUF2052 PF09747.9 GBG66226.1 - 0.0031 17.7 1.3 0.0031 17.7 1.3 3.1 2 1 1 3 3 3 1 Coiled-coil domain containing protein (DUF2052) RT_RNaseH_2 PF17919.1 GBG66227.1 - 4.5e-23 81.2 0.0 8.6e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66227.1 - 1.2e-22 80.2 0.0 2.2e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG66227.1 - 2.5e-07 31.3 0.0 4.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66227.1 - 4.1e-07 30.5 0.0 7.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG66227.1 - 1.6e-06 28.1 0.9 3.9e-06 26.9 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG66227.1 - 2.6e-05 24.0 0.0 4.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66227.1 - 4.1e-05 23.4 0.0 6.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG66227.1 - 0.0001 21.9 0.1 0.00019 21.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DHC_N1 PF08385.12 GBG66229.1 - 5.3e-133 444.6 0.2 7.6e-71 239.4 0.0 2.2 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 RT_RNaseH_2 PF17919.1 GBG66229.1 - 1.2e-21 76.6 0.0 3.5e-21 75.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66229.1 - 6.3e-21 74.6 0.0 1.9e-20 73.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66229.1 - 1.2e-20 74.0 0.0 2.8e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG66229.1 - 0.00052 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Menin PF05053.13 GBG66229.1 - 0.024 13.0 0.5 0.25 9.7 0.1 2.0 2 0 0 2 2 2 0 Menin DUF3584 PF12128.8 GBG66229.1 - 0.13 9.7 4.4 1.8 6.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TFIIA PF03153.13 GBG66229.1 - 2.8 7.8 5.8 4.5 7.2 5.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCHC PF00098.23 GBG66230.1 - 0.032 14.3 1.5 0.069 13.3 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG66232.1 - 6.7e-06 25.9 2.8 1.3e-05 25.1 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG66232.1 - 0.25 11.1 1.2 0.43 10.3 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Arf PF00025.21 GBG66233.1 - 3.9e-48 163.2 0.0 4.9e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GBG66233.1 - 1.8e-11 43.9 0.0 2.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG66233.1 - 1.6e-10 41.3 0.0 3.5e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GBG66233.1 - 5.1e-09 35.8 0.0 0.00019 20.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 GBG66233.1 - 4.9e-06 26.6 0.0 8.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GBG66233.1 - 9.9e-06 25.1 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GBG66233.1 - 0.00054 19.4 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Thymidylate_kin PF02223.17 GBG66233.1 - 0.01 15.5 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_22 PF13401.6 GBG66233.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 GBG66233.1 - 0.056 12.4 0.0 2.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 GBG66233.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 GBG66233.1 - 0.078 12.6 0.2 3 7.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 GBG66233.1 - 0.098 12.0 0.0 3.5 6.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family FixS PF03597.15 GBG66233.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type IU_nuc_hydro PF01156.19 GBG66234.1 - 7.5e-77 258.9 2.2 9e-77 258.6 2.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CDC14 PF08045.11 GBG66235.1 - 2e-10 40.2 0.0 3.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Myb_DNA-bind_4 PF13837.6 GBG66236.1 - 3.9e-07 30.4 1.5 7.7e-07 29.4 1.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG66236.1 - 0.1 12.9 0.9 0.24 11.7 0.9 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG66236.1 - 0.16 12.2 0.6 0.49 10.7 0.6 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF659 PF04937.15 GBG66238.1 - 2.3e-30 105.5 0.0 3.6e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG66239.1 - 3e-31 108.3 0.0 4.2e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pkinase_Tyr PF07714.17 GBG66240.1 - 1.1e-34 119.9 0.0 6.7e-33 114.1 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG66240.1 - 9.7e-34 116.9 0.0 3.2e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 GBG66240.1 - 8.8e-10 37.9 0.0 1.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG66240.1 - 1.2e-05 25.4 0.0 0.00021 21.3 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG66240.1 - 0.012 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ThiC-associated PF13667.6 GBG66240.1 - 0.12 12.2 0.1 26 4.7 0.0 2.7 2 0 0 2 2 2 0 ThiC-associated domain Kdo PF06293.14 GBG66240.1 - 0.14 11.5 0.1 0.39 10.0 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YceD PF02620.17 GBG66245.1 - 6.4e-30 103.8 1.1 1.1e-29 103.0 0.1 2.0 2 0 0 2 2 2 1 Large ribosomal RNA subunit accumulation protein YceD Exo_endo_phos PF03372.23 GBG66246.1 - 5.1e-16 58.9 0.3 3.9e-15 56.0 0.3 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family cwf18 PF08315.12 GBG66247.1 - 4.1e-23 82.5 2.4 1.3e-22 80.9 1.4 2.1 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor HEAT_2 PF13646.6 GBG66247.1 - 0.063 13.7 1.3 0.069 13.5 0.3 1.5 2 0 0 2 2 2 0 HEAT repeats DDE_Tnp_4 PF13359.6 GBG66248.1 - 2.3e-26 92.4 0.0 2.9e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66248.1 - 1.6e-12 47.5 0.0 2.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66248.1 - 0.00048 19.8 0.2 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG66248.1 - 0.045 14.1 0.1 0.11 12.9 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG66249.1 - 2.1e-08 34.4 2.0 2.1e-08 34.4 2.0 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG66249.1 - 0.00029 21.0 0.0 0.003 17.7 0.3 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG66249.1 - 0.0023 18.2 1.7 0.0032 17.7 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG66249.1 - 0.0075 16.3 0.4 0.014 15.4 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG66250.1 - 5.4e-29 100.9 0.0 7.9e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66250.1 - 6.6e-15 55.3 0.0 9e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66250.1 - 6.8e-05 22.6 0.2 0.15 11.7 0.2 2.7 3 0 0 3 3 3 2 Transposase DDE domain SPT6_acidic PF14632.6 GBG66251.1 - 0.05 14.2 10.8 0.075 13.6 10.8 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Nop53 PF07767.11 GBG66251.1 - 0.077 12.4 7.0 0.1 12.0 7.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RRN3 PF05327.11 GBG66251.1 - 1.6 7.2 6.1 2.1 6.8 6.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP90 PF00183.18 GBG66251.1 - 1.9 7.3 5.7 2.4 6.9 5.7 1.0 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.14 GBG66251.1 - 4.8 5.3 8.4 6.1 5.0 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG66251.1 - 8.2 4.4 9.5 9.7 4.1 9.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Fasciclin PF02469.22 GBG66252.1 - 4.9e-15 55.9 0.0 6.1e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain OmdA PF13376.6 GBG66252.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated RT_RNaseH PF17917.1 GBG66253.1 - 2.2e-28 98.6 0.0 4.2e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66253.1 - 2.2e-28 98.2 0.0 5.1e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66253.1 - 4.9e-12 45.8 0.0 8.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG66253.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MTS PF05175.14 GBG66254.1 - 0.00041 19.9 0.0 0.00068 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GBG66254.1 - 0.0016 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG66254.1 - 0.0059 17.3 0.0 0.016 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG66254.1 - 0.013 16.2 0.0 0.037 14.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 GBG66254.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 GBG66254.1 - 0.04 13.4 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.15 GBG66254.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G SAYSvFN PF10260.9 GBG66255.1 - 1.4e-07 31.3 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) ubiquitin PF00240.23 GBG66255.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family HSP90 PF00183.18 GBG66256.1 - 3.9e-188 626.6 8.4 5.4e-188 626.1 8.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GBG66256.1 - 9.6e-13 48.6 0.0 1.9e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GBG66256.1 - 1.6e-12 47.5 0.0 4.3e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 PF00183.18 GBG66257.1 - 1.1e-182 608.6 8.9 8.2e-177 589.2 3.9 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 GBG66257.1 - 9.6e-13 48.6 0.0 1.9e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GBG66257.1 - 1.6e-12 47.5 0.0 4.2e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UPF0184 PF03670.13 GBG66258.1 - 0.016 15.6 0.1 0.027 14.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DDE_Tnp_4 PF13359.6 GBG66259.1 - 5.5e-32 110.6 0.0 3.7e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66259.1 - 1.5e-16 60.6 0.0 3.3e-16 59.5 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66259.1 - 1.5e-06 28.0 0.9 0.099 12.3 0.0 3.2 3 0 0 3 3 3 3 Transposase DDE domain FA_hydroxylase PF04116.13 GBG66260.1 - 2.2e-28 99.2 12.0 4.3e-28 98.3 12.0 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DASH_Hsk3 PF08227.11 GBG66261.1 - 0.067 13.6 10.6 0.42 11.0 0.2 4.8 5 0 0 5 5 5 0 DASH complex subunit Hsk3 like HALZ PF02183.18 GBG66261.1 - 0.76 10.0 25.0 2.5 8.4 1.2 6.3 6 0 0 6 6 6 0 Homeobox associated leucine zipper GAS PF13851.6 GBG66261.1 - 2.7 7.3 83.4 1.4 8.3 4.2 5.2 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding IFT20 PF14931.6 GBG66262.1 - 0.047 13.9 11.4 0.092 12.9 11.4 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Lectin_N PF03954.14 GBG66262.1 - 0.41 10.4 7.4 38 4.0 0.1 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DASH_Dam1 PF08653.10 GBG66262.1 - 0.42 10.5 2.2 22 4.9 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 Prominin PF05478.11 GBG66262.1 - 0.76 7.7 10.4 1.6 6.6 10.4 1.5 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 GBG66262.1 - 0.85 9.7 7.0 0.63 10.1 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 GBG66262.1 - 1.9 8.8 10.9 0.29 11.4 1.6 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 GBG66262.1 - 2 8.9 6.6 20 5.6 1.0 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 GBG66262.1 - 2.8 8.5 15.8 18 5.8 7.6 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-Q PF13094.6 GBG66262.1 - 3.5 7.8 11.2 2.9 8.1 8.3 2.1 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit TMPIT PF07851.13 GBG66262.1 - 5.6 6.1 12.1 5.5 6.1 7.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein TP53IP5 PF15331.6 GBG66263.1 - 0.25 11.5 1.6 0.37 10.9 1.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Hid1 PF12722.7 GBG66263.1 - 2.8 6.0 3.4 3.5 5.7 3.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HALZ PF02183.18 GBG66264.1 - 0.03 14.5 17.8 2.2 8.6 1.2 4.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper DASH_Hsk3 PF08227.11 GBG66264.1 - 0.23 11.8 4.2 0.37 11.2 0.2 3.0 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like GAS PF13851.6 GBG66264.1 - 1.1 8.6 62.8 1.2 8.5 4.2 4.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 GBG66264.1 - 6.4 7.4 29.0 1 10.0 3.8 4.5 2 2 1 3 3 3 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.9 GBG66265.1 - 0.011 15.8 23.7 0.011 15.8 23.7 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 GBG66265.1 - 0.36 10.1 64.5 0.61 9.4 8.2 4.3 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DASH_Hsk3 PF08227.11 GBG66265.1 - 0.6 10.5 8.9 0.23 11.9 2.5 3.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Syntaxin-6_N PF09177.11 GBG66265.1 - 0.75 10.4 29.3 1.6 9.4 8.3 4.3 1 1 3 4 4 4 0 Syntaxin 6, N-terminal BRE1 PF08647.11 GBG66265.1 - 1.3 9.2 62.0 3 8.0 4.8 5.7 3 1 3 6 6 6 0 BRE1 E3 ubiquitin ligase HALZ PF02183.18 GBG66265.1 - 8.7 6.7 28.1 1.8 8.8 1.2 5.3 5 1 1 6 6 6 0 Homeobox associated leucine zipper DDE_Tnp_4 PF13359.6 GBG66266.1 - 2.7e-07 30.4 0.0 5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC45 PF02724.14 GBG66266.1 - 0.015 13.6 8.3 0.022 13.1 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG66266.1 - 0.26 9.8 15.9 0.38 9.3 15.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 GBG66266.1 - 0.45 9.3 2.3 0.64 8.8 2.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 GBG66266.1 - 1.2 7.9 5.6 1.7 7.3 5.6 1.2 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 GBG66266.1 - 2.6 7.4 15.5 3.9 6.8 15.5 1.1 1 0 0 1 1 1 0 SDA1 DUF659 PF04937.15 GBG66267.1 - 4.2e-07 29.9 0.0 7.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG66268.1 - 0.16 12.6 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease VIR_N PF15912.5 GBG66268.1 - 0.55 9.8 7.6 0.83 9.2 7.6 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal SDA1 PF05285.12 GBG66268.1 - 6.2 6.1 20.3 7.3 5.9 20.3 1.1 1 0 0 1 1 1 0 SDA1 ABC2_membrane PF01061.24 GBG66269.1 - 1.1e-41 142.6 12.7 1.6e-41 142.1 12.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GBG66269.1 - 8.1e-25 87.9 0.1 1.6e-24 87.0 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG66269.1 - 2.6e-06 26.8 5.4 5.2e-06 25.8 5.4 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG66269.1 - 9.6e-05 22.3 0.4 0.072 12.9 0.7 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GBG66269.1 - 0.0003 21.2 0.1 0.00063 20.2 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GBG66269.1 - 0.0042 17.0 0.2 0.0084 16.0 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GBG66269.1 - 0.0045 17.3 0.0 0.019 15.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GBG66269.1 - 0.0046 16.5 0.2 0.01 15.4 0.2 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 GBG66269.1 - 0.0086 16.0 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 GBG66269.1 - 0.0095 16.5 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GBG66269.1 - 0.011 15.5 0.3 0.032 13.9 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 GBG66269.1 - 0.015 14.3 0.1 0.028 13.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 GBG66269.1 - 0.016 15.1 0.3 0.031 14.2 0.3 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 GBG66269.1 - 0.03 14.6 0.1 0.088 13.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GBG66269.1 - 0.052 14.1 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GBG66269.1 - 0.06 13.4 0.4 0.14 12.3 0.4 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 GBG66269.1 - 0.09 12.5 0.2 0.3 10.8 0.3 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GBG66269.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_ATPase PF09818.9 GBG66269.1 - 0.12 11.1 0.1 0.22 10.3 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA PF00004.29 GBG66269.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GBG66269.1 - 0.17 12.0 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 GBG66269.1 - 1.4 8.2 6.9 2.8 7.1 6.6 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Na_trans_assoc PF06512.13 GBG66270.1 - 0.39 11.0 17.0 1.3 9.3 16.9 2.1 1 1 0 1 1 1 0 Sodium ion transport-associated Aconitase PF00330.20 GBG66271.1 - 2e-125 419.4 0.0 2.6e-125 419.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GBG66271.1 - 1.6e-43 148.2 0.0 2.8e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain NOG1_N PF17835.1 GBG66272.1 - 0.27 11.2 6.8 0.18 11.8 4.4 1.9 2 1 0 2 2 2 0 NOG1 N-terminal helical domain Cupin_8 PF13621.6 GBG66272.1 - 0.95 9.1 5.1 2.8 7.6 2.4 2.0 1 1 1 2 2 2 0 Cupin-like domain DUF4337 PF14235.6 GBG66272.1 - 1 9.4 9.5 3.6 7.7 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF16 PF01519.16 GBG66272.1 - 3.4 8.2 12.1 0.25 11.8 3.0 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 APG6_N PF17675.1 GBG66272.1 - 9.9 6.7 20.9 2.3 8.8 1.6 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region ANAPC4_WD40 PF12894.7 GBG66273.1 - 1.8e-11 44.1 2.5 0.15 12.4 0.0 6.8 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 GBG66273.1 - 0.0002 20.8 0.2 0.019 14.3 0.0 3.3 3 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 GBG66273.1 - 0.0039 18.0 27.3 0.2 12.6 0.1 9.7 9 1 1 10 10 10 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GBG66273.1 - 0.0048 15.9 0.1 7.5 5.4 0.0 4.6 5 1 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 GBG66273.1 - 0.02 14.6 0.2 4.3 7.0 0.0 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split Aa_trans PF01490.18 GBG66277.1 - 9.3e-43 146.5 9.7 1.1e-42 146.3 9.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.15 GBG66277.1 - 1.3 9.5 9.7 3 8.4 0.2 3.9 2 2 0 2 2 2 0 Domain of unknown function (DUF202) SHIPPO-rpt PF07004.12 GBG66279.1 - 4e-18 65.4 31.4 3.3e-05 24.6 1.2 5.3 5 0 0 5 5 5 5 Sperm-tail PG-rich repeat S-methyl_trans PF02574.16 GBG66280.1 - 1.8e-72 244.4 0.0 1.2e-71 241.7 0.0 1.9 1 1 0 1 1 1 1 Homocysteine S-methyltransferase RT_RNaseH PF17917.1 GBG66281.1 - 5.2e-57 190.6 0.2 6e-28 97.2 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66281.1 - 6.2e-53 177.0 0.0 5.2e-30 103.4 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66281.1 - 1.4e-31 108.3 5.5 2.4e-16 59.6 1.2 3.4 3 0 0 3 3 3 2 Integrase zinc binding domain rve PF00665.26 GBG66281.1 - 9.4e-31 106.5 0.0 2.1e-15 57.0 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG66281.1 - 2.8e-26 92.4 0.1 5.4e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG66281.1 - 1.5e-22 79.8 0.0 6.3e-06 26.0 0.0 3.5 3 0 0 3 3 3 3 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG66281.1 - 6e-21 74.9 0.0 9.3e-07 29.4 0.0 3.6 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.6 GBG66281.1 - 1.6e-16 60.6 0.0 4.8e-05 23.8 0.0 3.9 3 0 0 3 3 3 3 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG66281.1 - 4.7e-12 45.8 0.0 0.0061 16.3 0.0 3.6 3 0 0 3 3 3 3 Aspartyl protease zf-H2C2 PF09337.10 GBG66281.1 - 2.7e-06 27.5 0.1 0.052 13.8 0.0 2.9 2 0 0 2 2 2 2 H2C2 zinc finger DUF1758 PF05585.12 GBG66281.1 - 0.00031 20.6 0.1 0.029 14.2 0.0 2.5 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Rhamno_transf PF11316.8 GBG66281.1 - 0.0014 18.0 0.1 0.25 10.7 0.0 2.7 2 0 0 2 2 2 1 Putative rhamnosyl transferase SH3_16 PF18348.1 GBG66281.1 - 0.05 13.4 0.0 3 7.7 0.0 2.7 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain RVP PF00077.20 GBG66281.1 - 0.059 13.7 0.0 23 5.4 0.0 3.3 3 0 0 3 3 3 0 Retroviral aspartyl protease rve_3 PF13683.6 GBG66281.1 - 0.07 12.9 0.1 25 4.8 0.0 3.1 2 0 0 2 2 2 0 Integrase core domain CCD48 PF15799.5 GBG66281.1 - 0.3 9.4 3.1 0.52 8.6 3.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Phage_GPO PF05929.11 GBG66281.1 - 0.45 10.1 5.8 2.6 7.6 0.0 3.2 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase ZapB PF06005.12 GBG66281.1 - 0.46 11.0 4.8 1.6 9.2 2.9 2.8 2 0 0 2 2 2 0 Cell division protein ZapB GvpL_GvpF PF06386.11 GBG66281.1 - 1.5 8.7 7.4 3.4 7.5 7.4 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF SSP160 PF06933.11 GBG66281.1 - 8.8 4.4 9.1 20 3.2 9.1 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Myb_DNA-bind_4 PF13837.6 GBG66283.1 - 1.1e-06 28.9 0.4 2.6e-06 27.7 0.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HemY_N PF07219.13 GBG66283.1 - 0.31 11.3 3.0 0.86 9.8 1.4 2.2 2 0 0 2 2 2 0 HemY protein N-terminus PTPRCAP PF15713.5 GBG66284.1 - 0.014 15.7 20.6 0.022 15.1 20.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Mpp10 PF04006.12 GBG66284.1 - 0.039 12.4 21.0 0.047 12.1 21.0 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 GBG66284.1 - 0.04 13.3 23.1 0.049 13.0 23.1 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG66284.1 - 0.047 13.3 10.3 0.054 13.1 10.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG66284.1 - 0.31 9.2 25.1 0.36 9.0 25.1 1.0 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 GBG66284.1 - 0.33 11.2 15.4 0.43 10.8 15.4 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG66284.1 - 0.41 10.0 25.6 0.51 9.7 25.6 1.1 1 0 0 1 1 1 0 SDA1 Menin PF05053.13 GBG66284.1 - 0.56 8.5 4.5 0.69 8.2 4.5 1.1 1 0 0 1 1 1 0 Menin RRN3 PF05327.11 GBG66284.1 - 0.95 7.9 9.5 1.1 7.8 9.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SLC12 PF03522.15 GBG66284.1 - 1.3 8.0 3.4 1.4 7.9 3.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.12 GBG66284.1 - 1.3 8.0 13.9 1.6 7.7 13.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Pes-10 PF07149.11 GBG66284.1 - 1.3 8.0 19.4 1.6 7.7 19.4 1.2 1 0 0 1 1 1 0 Pes-10 SAPS PF04499.15 GBG66284.1 - 1.5 7.5 6.5 1.6 7.4 6.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 GBG66284.1 - 1.7 6.9 19.3 2 6.6 19.3 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG66284.1 - 3.1 7.9 25.6 4.2 7.4 25.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NPR3 PF03666.13 GBG66284.1 - 6.2 5.5 7.8 7.6 5.2 7.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GBG66284.1 - 6.5 5.4 12.0 7.7 5.2 12.0 1.1 1 0 0 1 1 1 0 Presenilin Thioredoxin PF00085.20 GBG66287.1 - 8.5e-22 77.1 0.0 1.8e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG66287.1 - 5.1e-05 23.7 0.1 0.0006 20.2 0.1 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG66287.1 - 0.00057 20.2 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GBG66287.1 - 0.0011 19.1 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 GBG66287.1 - 0.0042 17.0 0.1 0.0091 15.9 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family AnfO_nitrog PF09582.10 GBG66287.1 - 0.0086 15.4 0.9 0.0086 15.4 0.9 2.8 3 0 0 3 3 3 1 Iron only nitrogenase protein AnfO (AnfO_nitrog) OST3_OST6 PF04756.13 GBG66287.1 - 0.0089 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family T4_deiodinase PF00837.17 GBG66287.1 - 0.0097 15.2 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase Redoxin PF08534.10 GBG66287.1 - 0.016 14.9 0.1 0.036 13.8 0.0 1.6 2 0 0 2 2 2 0 Redoxin SDA1 PF05285.12 GBG66287.1 - 0.064 12.7 28.3 0.011 15.2 19.3 2.1 2 0 0 2 2 2 0 SDA1 Presenilin PF01080.17 GBG66287.1 - 0.78 8.4 19.9 0.27 9.9 10.0 2.1 2 0 0 2 2 2 0 Presenilin Spt20 PF12090.8 GBG66287.1 - 3.2 7.3 16.1 0.37 10.4 7.6 2.1 2 0 0 2 2 2 0 Spt20 family Retrotrans_gag PF03732.17 GBG66289.1 - 0.0035 17.6 4.1 0.0042 17.3 0.0 3.1 4 0 0 4 4 4 1 Retrotransposon gag protein ZapB PF06005.12 GBG66289.1 - 0.36 11.3 0.1 0.36 11.3 0.1 3.5 3 0 0 3 3 3 0 Cell division protein ZapB RNR_Alpha PF17975.1 GBG66289.1 - 0.43 11.1 3.2 0.6 10.6 0.0 2.6 3 0 0 3 3 3 0 Ribonucleotide reductase alpha domain PRKG1_interact PF15898.5 GBG66289.1 - 2 9.3 7.2 1.5 9.8 0.3 2.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain CLZ PF16526.5 GBG66289.1 - 7.3 7.0 10.7 0.4 11.1 0.7 3.5 4 1 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DAGK_cat PF00781.24 GBG66291.1 - 0.074 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Integrase_H2C2 PF17921.1 GBG66292.1 - 2.5e-14 53.1 0.0 1.2e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG66292.1 - 3.7e-07 29.9 0.0 6.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG66292.1 - 4e-05 23.8 0.0 8.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG66292.1 - 0.00032 20.9 0.0 0.00081 19.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG66293.1 - 2.3e-17 62.9 0.0 6.9e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66293.1 - 1.4e-09 38.1 0.0 3.8e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG66293.1 - 4.3e-09 36.2 0.0 8.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG66293.1 - 2e-08 34.8 0.0 6.1e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG66293.1 - 3.9e-08 33.1 0.1 7.4e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG66293.1 - 6.9e-07 29.7 0.0 2.8e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG66293.1 - 0.0018 18.5 0.1 0.022 15.0 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG66293.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG66293.1 - 0.041 14.2 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG66294.1 - 1.6e-35 122.7 0.1 3.6e-35 121.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66294.1 - 1.1e-17 63.9 0.0 5.9e-17 61.5 0.0 2.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG66294.1 - 2.3e-14 53.5 0.4 0.018 15.9 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat RT_RNaseH PF17917.1 GBG66294.1 - 5.3e-08 33.1 0.0 1.7e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ANAPC4_WD40 PF12894.7 GBG66294.1 - 0.0019 18.4 0.0 0.92 9.9 0.0 2.7 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Chromo PF00385.24 GBG66294.1 - 0.015 15.2 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Casc1_N PF15927.5 GBG66294.1 - 0.6 9.8 11.9 1.5 8.5 11.9 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus CHD5 PF04420.14 GBG66294.1 - 0.75 9.6 2.6 1.6 8.6 2.6 1.5 1 0 0 1 1 1 0 CHD5-like protein Histone PF00125.24 GBG66295.1 - 2e-19 70.2 0.4 2e-19 70.2 0.4 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 RVT_1 PF00078.27 GBG66296.1 - 1e-13 51.4 0.0 1.4e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cwf_Cwc_15 PF04889.12 GBG66297.1 - 2.8e-72 243.4 24.2 2.7e-71 240.2 24.2 1.9 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CCB2_CCB4 PF11152.8 GBG66298.1 - 2.9e-32 111.6 0.1 4.4e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 HAD_2 PF13419.6 GBG66299.1 - 4.9e-18 65.8 0.0 8.7e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GBG66299.1 - 6.9e-09 36.3 0.0 9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG66299.1 - 1.1e-08 35.0 0.0 2.7e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GBG66299.1 - 0.043 14.2 0.1 0.082 13.3 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Daxx PF03344.15 GBG66299.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain Macoilin PF09726.9 GBG66299.1 - 7.4 5.0 7.2 11 4.4 7.2 1.2 1 0 0 1 1 1 0 Macoilin family FAM76 PF16046.5 GBG66299.1 - 8.2 5.7 7.5 37 3.5 4.9 2.2 2 0 0 2 2 2 0 FAM76 protein HAUS2 PF15003.6 GBG66301.1 - 4.2e-55 186.5 0.0 5.8e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Isochorismatase PF00857.20 GBG66303.1 - 1.1e-41 143.0 0.0 3.1e-24 86.1 0.0 2.6 2 0 0 2 2 2 2 Isochorismatase family NeuB PF03102.14 GBG66303.1 - 0.093 12.2 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 NeuB family Isochorismatase PF00857.20 GBG66304.1 - 1.4e-05 25.4 0.0 1.8e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Retrotrans_gag PF03732.17 GBG66305.1 - 4.2e-05 23.7 2.4 0.058 13.7 0.0 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG66305.1 - 0.011 16.2 0.1 0.041 14.4 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66305.1 - 0.012 16.3 0.0 0.14 12.8 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease Asp_protease PF09668.10 GBG66305.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG66306.1 - 3.6e-31 108.4 0.0 5.4e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG66306.1 - 1.6e-09 38.0 0.1 3.4e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG66307.1 - 8.8e-26 90.8 0.1 1.3e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66307.1 - 1.9e-25 88.8 0.0 4.4e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66307.1 - 6.1e-24 84.3 0.0 1.2e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66307.1 - 2.8e-16 59.3 0.2 5.6e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG66307.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Prim_Zn_Ribbon PF08273.12 GBG66307.1 - 0.77 10.1 4.4 1.6 9.1 0.9 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase CLIP1_ZNF PF16641.5 GBG66307.1 - 0.8 9.7 2.7 2 8.4 2.7 1.6 1 0 0 1 1 1 0 CLIP1 zinc knuckle BUD22 PF09073.10 GBG66308.1 - 1.2 8.4 14.0 1.6 8.0 14.0 1.2 1 0 0 1 1 1 0 BUD22 Apis_Csd PF11671.8 GBG66309.1 - 5.3 7.1 21.1 0.41 10.6 2.3 2.2 2 0 0 2 2 2 0 Complementary sex determiner protein WD40 PF00400.32 GBG66310.1 - 9.5e-15 54.8 14.2 7.1e-05 23.5 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 GBG66310.1 - 3.2e-14 52.9 0.2 1.1e-13 51.2 0.0 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 GBG66310.1 - 2.2e-05 24.7 0.1 0.00041 20.6 0.1 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain FAM176 PF14851.6 GBG66310.1 - 0.022 14.4 0.3 0.054 13.1 0.3 1.6 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 GBG66310.1 - 0.048 12.0 2.4 0.075 11.3 2.4 1.3 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG66310.1 - 0.45 10.6 9.0 0.031 14.4 2.5 1.9 2 0 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.12 GBG66310.1 - 0.52 8.5 5.3 0.76 7.9 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG66310.1 - 1 7.4 12.0 1.6 6.7 12.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GBG66310.1 - 5 5.5 5.0 7 5.1 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 GBG66310.1 - 7.1 5.9 8.6 14 4.9 8.6 1.4 1 0 0 1 1 1 0 NOA36 protein O-FucT PF10250.9 GBG66311.1 - 8.6e-48 163.7 0.0 1.4e-47 163.1 0.0 1.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase AAA_26 PF13500.6 GBG66312.1 - 1.6e-19 70.5 0.0 2.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 GBG66312.1 - 2.4e-11 43.3 0.0 4.9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 DRTGG domain SecA_PP_bind PF01043.20 GBG66312.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.4 1 0 0 1 1 1 0 SecA preprotein cross-linking domain PTA_PTB PF01515.19 GBG66313.1 - 1.7e-125 418.6 1.6 2e-125 418.3 1.6 1.0 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase RT_RNaseH_2 PF17919.1 GBG66314.1 - 1.6e-22 79.4 0.0 2.9e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66314.1 - 3.6e-22 78.6 0.2 1.1e-21 77.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Radical_SAM PF04055.21 GBG66314.1 - 1.5e-13 51.4 0.0 1.4e-12 48.3 0.0 2.4 1 1 0 1 1 1 1 Radical SAM superfamily MMR_HSR1 PF01926.23 GBG66314.1 - 2.9e-11 43.5 0.1 1.6e-09 37.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase HemN_C PF06969.16 GBG66314.1 - 1.2e-08 34.9 0.1 2.9e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 HemN C-terminal domain RsgA_GTPase PF03193.16 GBG66314.1 - 3.6e-06 27.0 0.1 1.2e-05 25.3 0.1 1.9 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 GBG66314.1 - 0.0009 18.8 0.1 0.97 8.9 0.0 2.8 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GBG66314.1 - 0.042 13.4 1.6 1.2 8.7 0.2 3.0 2 1 0 2 2 2 0 Ferrous iron transport protein B PTPRCAP PF15713.5 GBG66315.1 - 0.14 12.4 21.3 0.19 12.0 21.3 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FCP1_C PF09309.10 GBG66315.1 - 0.67 9.8 17.3 0.73 9.7 17.3 1.0 1 0 0 1 1 1 0 FCP1, C-terminal RNA_polI_A34 PF08208.11 GBG66315.1 - 1.9 8.5 15.9 2.4 8.2 15.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 GBG66315.1 - 2.6 6.2 14.4 2.7 6.2 14.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG66315.1 - 5.5 5.7 8.1 5.8 5.6 8.1 1.0 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG66315.1 - 6.6 4.8 16.5 7.6 4.6 16.5 1.0 1 0 0 1 1 1 0 Nop14-like family FSAP_sig_propep PF03032.15 GBG66315.1 - 9.4 6.4 32.7 2.8 8.0 14.1 2.5 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide HLH PF00010.26 GBG66316.1 - 7.1e-10 38.7 1.8 8.8e-10 38.4 0.4 1.9 2 0 0 2 2 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 GBG66316.1 - 2e-05 24.9 5.8 2e-05 24.9 5.8 2.1 2 0 0 2 2 2 1 Cell division protein ZapB DivIC PF04977.15 GBG66316.1 - 0.00055 19.7 4.5 0.00055 19.7 4.5 2.1 2 0 0 2 2 2 1 Septum formation initiator TMF_DNA_bd PF12329.8 GBG66316.1 - 0.0015 18.5 10.5 0.0015 18.5 10.5 1.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding YabA PF06156.13 GBG66316.1 - 0.0019 18.8 1.0 0.0019 18.8 1.0 1.7 2 0 0 2 2 2 1 Initiation control protein YabA DUF5082 PF16888.5 GBG66316.1 - 0.0037 17.5 4.3 0.0079 16.5 4.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) DUF3450 PF11932.8 GBG66316.1 - 0.015 14.7 4.1 0.015 14.7 4.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 GBG66316.1 - 0.015 14.2 3.8 0.015 14.2 3.8 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein TMCO5 PF14992.6 GBG66316.1 - 0.039 13.5 6.2 0.051 13.1 6.2 1.2 1 0 0 1 1 1 0 TMCO5 family COG7 PF10191.9 GBG66316.1 - 0.04 12.1 1.3 0.069 11.4 1.3 1.3 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF3053 PF11254.8 GBG66316.1 - 0.14 11.8 1.2 0.19 11.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Macoilin PF09726.9 GBG66316.1 - 0.2 10.2 8.1 0.25 9.9 8.1 1.0 1 0 0 1 1 1 0 Macoilin family CtIP_N PF10482.9 GBG66316.1 - 0.39 10.8 12.5 9.7 6.3 12.5 2.8 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain FtsL PF04999.13 GBG66316.1 - 0.54 10.3 3.9 0.27 11.3 1.4 1.7 2 0 0 2 2 2 0 Cell division protein FtsL CENP-H PF05837.12 GBG66316.1 - 0.65 10.4 10.7 0.07 13.5 5.8 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4140 PF13600.6 GBG66316.1 - 0.78 10.2 7.8 0.79 10.2 6.4 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.11 GBG66316.1 - 0.85 9.8 15.0 2.1 8.6 15.0 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) EMC3_TMCO1 PF01956.16 GBG66316.1 - 1.5 8.6 2.6 1 9.1 1.0 1.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like FAM76 PF16046.5 GBG66316.1 - 1.7 7.9 10.1 2.3 7.5 10.1 1.1 1 0 0 1 1 1 0 FAM76 protein TPR_MLP1_2 PF07926.12 GBG66316.1 - 3.6 7.7 13.0 0.083 12.9 4.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein JIP_LZII PF16471.5 GBG66316.1 - 5.7 7.2 12.1 12 6.1 8.9 2.7 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II TMPIT PF07851.13 GBG66316.1 - 6.2 6.0 6.4 0.48 9.6 1.3 1.6 2 0 0 2 2 2 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 GBG66316.1 - 6.3 7.1 14.2 1.3 9.3 7.5 2.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 GBG66316.1 - 6.4 7.3 16.2 14 6.2 15.8 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1475 PF07343.11 GBG66317.1 - 5.4e-28 98.4 2.1 6.5e-28 98.2 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1475) DUF2834 PF11196.8 GBG66317.1 - 0.0022 18.3 3.1 0.0031 17.8 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2834) Acyl-CoA_dh_1 PF00441.24 GBG66317.1 - 0.0086 16.3 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PhnA_Zn_Ribbon PF08274.12 GBG66318.1 - 0.0017 18.2 0.5 0.0053 16.7 0.5 1.8 1 0 0 1 1 1 1 PhnA Zinc-Ribbon ORC5_C PF14630.6 GBG66319.1 - 2.9e-29 102.5 0.0 2.3e-25 89.7 0.0 2.5 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 GBG66319.1 - 8.1e-09 36.1 0.0 6.2e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG66319.1 - 0.01 16.1 0.0 0.097 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GBG66319.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 GBG66319.1 - 0.21 11.9 0.0 0.4 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Integrase_H2C2 PF17921.1 GBG66321.1 - 4e-14 52.5 0.0 1.7e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG66321.1 - 3.5e-13 49.8 0.0 1e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG66321.1 - 0.0019 18.4 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG66321.1 - 0.0046 17.6 0.0 0.01 16.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG66322.1 - 6.9e-30 104.2 0.1 1e-29 103.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG66322.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG66322.1 - 0.00032 20.9 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Cytochrom_C PF00034.21 GBG66323.1 - 1.9 9.7 6.1 20 6.4 0.2 2.8 2 1 0 2 2 2 0 Cytochrome c Usp PF00582.26 GBG66324.1 - 0.68 10.4 10.8 5.1 7.6 4.5 2.4 2 0 0 2 2 2 0 Universal stress protein family SNARE PF05739.19 GBG66325.1 - 5.6e-14 51.9 0.4 5.6e-14 51.9 0.4 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 GBG66325.1 - 2.5e-06 27.3 12.3 0.0026 17.5 0.6 2.3 2 0 0 2 2 2 2 Syntaxin T2SSF PF00482.23 GBG66325.1 - 0.15 12.0 1.9 0.41 10.6 1.9 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F UPF0242 PF06785.11 GBG66325.1 - 0.22 11.6 5.6 3.3 7.8 2.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 GBG66325.1 - 0.66 10.3 5.2 0.65 10.3 0.3 3.2 2 2 2 4 4 4 0 ABC transporter C-terminal domain Prominin PF05478.11 GBG66325.1 - 2 6.3 6.9 0.38 8.7 0.2 2.0 2 0 0 2 2 2 0 Prominin SKA1 PF07160.12 GBG66325.1 - 2.7 7.8 7.4 2 8.2 0.7 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1664 PF07889.12 GBG66325.1 - 5.1 7.1 8.3 1.6 8.7 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RVT_1 PF00078.27 GBG66326.1 - 1.3e-29 103.3 0.0 2e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG66326.1 - 9.4e-12 44.7 0.0 1.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain UCR_14kD PF02271.16 GBG66326.1 - 1.1 9.3 3.1 0.63 10.0 0.6 1.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit RVT_1 PF00078.27 GBG66327.1 - 1.9e-30 106.1 0.0 2.5e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG66327.1 - 0.06 13.3 0.0 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L34 ERO1 PF04137.15 GBG66328.1 - 1.6e-77 261.1 0.0 1e-60 205.9 0.0 2.0 1 1 0 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RT_RNaseH PF17917.1 GBG66328.1 - 0.00028 21.1 0.0 0.0049 17.1 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66328.1 - 0.00031 20.7 0.0 0.0017 18.3 0.0 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase ERO1 PF04137.15 GBG66329.1 - 6e-78 262.5 0.0 3.3e-61 207.4 0.0 2.0 1 1 1 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RT_RNaseH_2 PF17919.1 GBG66329.1 - 0.00043 20.3 0.0 0.0017 18.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66329.1 - 0.00077 19.7 0.0 0.0051 17.1 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66330.1 - 1.1e-31 108.8 0.1 1.4e-15 57.2 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66330.1 - 5.5e-21 75.1 0.0 9.7e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66330.1 - 1e-20 74.0 0.0 2.8e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66330.1 - 1.1e-11 44.9 0.0 3.2e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG66330.1 - 0.0087 16.7 0.0 0.026 15.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG66332.1 - 1.1e-13 51.3 6.1 6.2e-08 32.9 2.1 2.9 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG66332.1 - 0.00046 20.5 0.4 0.16 12.3 0.4 2.7 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like TFIIF_alpha PF05793.12 GBG66332.1 - 0.0012 17.5 37.8 0.0012 17.5 37.8 3.2 4 0 0 4 4 4 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Myb_DNA-bind_5 PF13873.6 GBG66332.1 - 0.059 13.4 4.4 2.5 8.2 2.2 2.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG66334.1 - 2.3e-17 63.3 0.0 3.7e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG66334.1 - 1.8e-05 24.4 0.1 3.5e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2457 PF10446.9 GBG66335.1 - 0.016 14.4 9.5 0.019 14.2 9.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Myb_DNA-bind_4 PF13837.6 GBG66336.1 - 0.0004 20.7 0.1 0.00075 19.8 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zinc_ribbon_12 PF11331.8 GBG66338.1 - 1.2e-06 28.2 2.0 1.2e-06 28.2 2.0 2.6 2 0 0 2 2 2 1 Probable zinc-ribbon domain zf-ribbon_3 PF13248.6 GBG66338.1 - 0.0027 17.1 1.5 0.015 14.7 1.5 2.5 1 0 0 1 1 1 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 GBG66338.1 - 0.012 15.1 0.9 0.039 13.5 0.9 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding zf-Mss51 PF13824.6 GBG66338.1 - 0.11 12.7 0.8 0.42 10.7 0.8 2.1 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SlyX PF04102.12 GBG66338.1 - 0.13 12.9 1.5 15 6.3 0.1 3.3 3 0 0 3 3 3 0 SlyX Retrotrans_gag PF03732.17 GBG66338.1 - 0.16 12.3 0.4 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein HypA PF01155.19 GBG66338.1 - 0.22 11.5 3.4 3.4 7.7 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_recom PF13408.6 GBG66338.1 - 1.8 9.1 3.6 4.7 7.8 0.0 2.7 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain OrfB_Zn_ribbon PF07282.11 GBG66338.1 - 7.4 6.6 6.3 2.4 8.1 0.3 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain C2 PF00168.30 GBG66339.1 - 3.6e-19 69.0 0.0 6e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 GBG66339.1 - 1.2e-07 31.4 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MMM1 PF10296.9 GBG66339.1 - 0.0039 16.3 0.0 0.051 12.6 0.0 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 GCFC PF07842.12 GBG66339.1 - 0.011 15.4 0.5 0.017 14.8 0.5 1.2 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein DUF155 PF02582.14 GBG66339.1 - 0.13 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 RVT_1 PF00078.27 GBG66342.1 - 3e-27 95.6 0.1 4.4e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG66342.1 - 3.4e-06 27.5 0.0 6.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66342.1 - 1.8e-05 25.3 0.0 3.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG66342.1 - 2e-05 24.4 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66342.1 - 0.00087 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG66344.1 - 6.5e-12 45.2 0.0 1.6e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG66344.1 - 3e-10 40.3 0.0 6.5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RNase_PH PF01138.21 GBG66345.1 - 0.06 13.9 0.1 0.097 13.2 0.1 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 Macoilin PF09726.9 GBG66345.1 - 0.17 10.4 0.5 0.18 10.4 0.5 1.1 1 0 0 1 1 1 0 Macoilin family RVT_1 PF00078.27 GBG66346.1 - 2.8e-25 89.2 0.0 4.5e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66346.1 - 1e-15 57.6 0.8 5.3e-15 55.3 0.1 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG66346.1 - 9.4e-12 45.2 0.2 5e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG66346.1 - 2.3e-05 24.5 0.0 6.6e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG66346.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain BLOC1_2 PF10046.9 GBG66348.1 - 0.19 12.0 1.7 0.47 10.8 0.4 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-CCHC PF00098.23 GBG66349.1 - 0.014 15.4 0.6 0.014 15.4 0.6 1.9 2 0 0 2 2 2 0 Zinc knuckle Totivirus_coat PF05518.11 GBG66349.1 - 5.2 5.0 14.5 11 3.9 14.5 1.7 1 0 0 1 1 1 0 Totivirus coat protein Retrotrans_gag PF03732.17 GBG66350.1 - 0.00036 20.8 1.8 0.6 10.4 0.1 2.5 2 0 0 2 2 2 2 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG66351.1 - 4.2e-09 36.9 0.0 2.1e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66351.1 - 1.7e-08 35.0 0.0 8.1e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG66351.1 - 2.2e-06 27.5 0.0 9.8e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG66351.1 - 4.9e-05 23.5 11.2 0.42 10.9 0.2 4.7 4 0 0 4 4 4 3 Retrotransposon gag protein Asp_protease PF09668.10 GBG66351.1 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease FlxA PF14282.6 GBG66351.1 - 0.0041 17.1 0.3 0.0041 17.1 0.3 3.2 3 1 0 3 3 3 1 FlxA-like protein SlyX PF04102.12 GBG66351.1 - 0.15 12.7 14.6 0.16 12.6 0.1 3.6 3 0 0 3 3 3 0 SlyX FAM76 PF16046.5 GBG66351.1 - 2.1 7.6 4.2 3.8 6.8 4.2 1.3 1 0 0 1 1 1 0 FAM76 protein Integrase_H2C2 PF17921.1 GBG66352.1 - 0.00018 21.5 0.1 0.00033 20.7 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DUF3410 PF11890.8 GBG66354.1 - 0.13 12.1 1.0 0.53 10.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Dimer_Tnp_hAT PF05699.14 GBG66355.1 - 4e-05 23.3 0.3 7.1e-05 22.5 0.3 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG66356.1 - 9.2e-30 103.8 0.1 1.6e-29 103.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG66356.1 - 6.3e-08 33.2 0.0 3.5e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66356.1 - 2.1e-05 25.0 0.0 8.1e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF3006 PF11213.8 GBG66356.1 - 0.00028 21.0 2.7 0.00071 19.8 2.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) RVP_2 PF08284.11 GBG66356.1 - 0.00034 20.4 0.0 0.00077 19.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG66356.1 - 0.0021 18.3 3.1 0.068 13.5 0.0 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein SPARC_Ca_bdg PF10591.9 GBG66356.1 - 0.0057 17.0 0.7 0.035 14.4 0.7 2.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Asp_protease PF09668.10 GBG66356.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Caldesmon PF02029.15 GBG66357.1 - 0.62 8.8 32.8 0.73 8.5 32.8 1.0 1 0 0 1 1 1 0 Caldesmon Presenilin PF01080.17 GBG66357.1 - 4.6 5.9 13.6 5.3 5.7 13.6 1.1 1 0 0 1 1 1 0 Presenilin Pec_lyase_C PF00544.19 GBG66359.1 - 0.27 10.8 1.7 0.53 9.8 0.2 1.9 2 0 0 2 2 2 0 Pectate lyase RT_RNaseH PF17917.1 GBG66362.1 - 1.2e-26 93.0 0.1 2.7e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66362.1 - 1.6e-25 89.0 0.0 2.9e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66362.1 - 2.4e-11 43.9 0.0 7e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG66362.1 - 0.00019 21.1 0.1 0.0017 18.1 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain MOR2-PAG1_N PF14222.6 GBG66362.1 - 0.015 14.3 0.0 0.033 13.2 0.0 1.5 2 0 0 2 2 2 0 Cell morphogenesis N-terminal Myb_DNA-bind_4 PF13837.6 GBG66362.1 - 0.035 14.5 1.2 0.13 12.6 1.2 2.0 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain CDH1_2_SANT_HL1 PF18375.1 GBG66362.1 - 0.33 11.6 1.7 16 6.3 0.1 2.7 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Integrase_H2C2 PF17921.1 GBG66363.1 - 2.5e-17 62.7 0.3 4.8e-17 61.8 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66363.1 - 4.3e-11 43.1 0.0 7.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG66363.1 - 0.0096 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG66363.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) BCOR PF15808.5 GBG66365.1 - 0.11 12.7 6.3 0.6 10.3 6.3 2.1 1 1 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region NPR3 PF03666.13 GBG66366.1 - 0.57 8.9 3.2 0.72 8.6 3.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4788 PF16032.5 GBG66367.1 - 0.21 10.5 0.6 1.7 7.5 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4788) DUF3541 PF12060.8 GBG66368.1 - 0.11 12.2 0.4 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) TMPIT PF07851.13 GBG66368.1 - 0.93 8.7 2.2 2 7.6 2.2 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF4140 PF13600.6 GBG66368.1 - 5.2 7.6 8.2 24 5.4 2.2 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.22 GBG66368.1 - 6.1 7.1 11.8 0.56 10.5 2.5 3.0 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain MbeD_MobD PF04899.12 GBG66368.1 - 7.9 6.7 7.6 3.7 7.7 1.5 3.0 3 1 0 3 3 3 0 MbeD/MobD like DivIC PF04977.15 GBG66368.1 - 9.7 6.1 16.1 1.4 8.7 0.5 4.1 3 1 1 4 4 4 0 Septum formation initiator DUF659 PF04937.15 GBG66369.1 - 7.7e-19 68.1 0.0 1.3e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) BUD22 PF09073.10 GBG66372.1 - 2.4 7.4 10.7 3.5 6.9 10.7 1.3 1 0 0 1 1 1 0 BUD22 RT_RNaseH_2 PF17919.1 GBG66374.1 - 1.2e-30 105.4 0.0 2.1e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66374.1 - 1.9e-29 102.0 0.2 3.2e-29 101.3 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myc_N PF01056.18 GBG66374.1 - 0.015 15.2 8.9 0.022 14.7 8.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4746 PF15928.5 GBG66374.1 - 0.022 14.2 9.6 0.03 13.8 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 GBG66374.1 - 0.06 13.6 15.1 0.089 13.0 15.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 S-antigen PF05756.11 GBG66374.1 - 0.068 13.5 9.2 0.15 12.5 9.2 1.5 1 0 0 1 1 1 0 S-antigen protein CPSF100_C PF13299.6 GBG66374.1 - 0.12 12.5 7.2 0.21 11.8 7.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NOA36 PF06524.12 GBG66374.1 - 0.15 11.3 12.8 0.23 10.8 12.8 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GBG66374.1 - 0.24 9.6 15.5 0.31 9.2 15.5 1.1 1 0 0 1 1 1 0 Nop14-like family RPN2_C PF18004.1 GBG66374.1 - 0.24 11.3 10.0 0.42 10.5 10.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_polI_A34 PF08208.11 GBG66374.1 - 0.5 10.4 10.3 0.82 9.7 10.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CobT PF06213.12 GBG66374.1 - 0.55 9.6 11.4 0.81 9.0 11.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 GBG66374.1 - 0.58 9.5 15.2 0.94 8.8 15.2 1.3 1 0 0 1 1 1 0 SDA1 AIM3 PF17096.5 GBG66374.1 - 0.7 10.9 2.8 1.5 9.8 2.8 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DNA_pol_phi PF04931.13 GBG66374.1 - 0.77 7.8 17.8 0.97 7.4 17.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 GBG66374.1 - 1.8 7.0 18.0 2.5 6.6 18.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.11 GBG66374.1 - 1.9 6.5 6.7 3.8 5.5 5.8 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen TFB6 PF17110.5 GBG66374.1 - 1.9 8.2 6.9 3.7 7.3 6.9 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH ORC_WH_C PF18137.1 GBG66374.1 - 2 8.5 7.5 5 7.2 7.5 1.7 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Presenilin PF01080.17 GBG66374.1 - 2.4 6.8 4.2 3.6 6.3 4.2 1.2 1 0 0 1 1 1 0 Presenilin Radial_spoke PF04712.12 GBG66374.1 - 2.4 7.0 15.7 3.6 6.4 15.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Connexin PF00029.19 GBG66374.1 - 4.5 7.0 5.5 1.6 8.4 3.2 1.4 2 0 0 2 2 2 0 Connexin CDC45 PF02724.14 GBG66374.1 - 8.4 4.6 12.2 11 4.1 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 GBG66374.1 - 8.7 6.0 12.8 15 5.3 12.8 1.3 1 0 0 1 1 1 0 FAM176 family DUF659 PF04937.15 GBG66375.1 - 1.9e-09 37.6 0.0 2.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG66377.1 - 1.5e-25 90.1 0.1 3.2e-25 88.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG66377.1 - 0.0051 17.1 0.2 0.0051 17.1 0.2 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG66378.1 - 1.2e-27 95.9 0.0 3.1e-27 94.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66378.1 - 5.4e-26 90.9 0.0 1.2e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66378.1 - 1.4e-14 54.2 0.0 2.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fib_alpha PF08702.10 GBG66378.1 - 0.021 15.0 1.9 0.49 10.6 0.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HNH_3 PF13392.6 GBG66378.1 - 0.12 12.1 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 HNH endonuclease APG17 PF04108.12 GBG66378.1 - 0.15 11.1 0.2 0.28 10.2 0.0 1.5 2 0 0 2 2 2 0 Autophagy protein Apg17 rve PF00665.26 GBG66380.1 - 6.3e-12 45.7 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_2 PF13696.6 GBG66380.1 - 0.0043 16.9 0.6 0.0078 16.0 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG66380.1 - 0.0072 16.9 0.1 0.018 15.6 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66380.1 - 0.011 16.3 0.1 0.043 14.4 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 GBG66380.1 - 0.051 13.9 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66380.1 - 0.082 12.7 0.3 0.27 11.0 0.1 1.9 2 0 0 2 2 2 0 Aspartyl protease rve_3 PF13683.6 GBG66380.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Fur_reg_FbpB PF13040.6 GBG66380.1 - 0.13 11.8 0.5 0.32 10.6 0.5 1.6 1 0 0 1 1 1 0 Fur-regulated basic protein B zf-CCHC PF00098.23 GBG66380.1 - 4 7.7 6.7 0.4 10.9 1.9 1.9 2 0 0 2 2 2 0 Zinc knuckle Presenilin PF01080.17 GBG66381.1 - 0.091 11.5 4.7 0.14 10.9 4.7 1.3 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 GBG66381.1 - 0.24 11.1 1.9 0.5 10.1 1.9 1.5 1 0 0 1 1 1 0 Connexin RNA_pol_Rpc4 PF05132.14 GBG66381.1 - 1.6 9.2 7.9 0.081 13.4 2.1 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Nop14 PF04147.12 GBG66381.1 - 2.5 6.2 38.3 4 5.5 38.3 1.2 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG66382.1 - 3.2e-27 95.5 0.0 5.8e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66382.1 - 8.3e-26 89.9 0.0 8.5e-25 86.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66382.1 - 2.9e-23 82.1 0.0 7.2e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66382.1 - 0.00011 22.3 0.1 0.00032 20.7 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG66382.1 - 0.00013 22.2 3.0 0.031 14.5 0.0 3.7 3 0 0 3 3 3 2 Retrotransposon gag protein DUF4407 PF14362.6 GBG66382.1 - 0.044 13.1 11.9 1.4 8.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cytochrom_c3_2 PF14537.6 GBG66382.1 - 0.9 10.1 9.5 0.06 13.8 3.9 2.0 2 0 0 2 2 2 0 Cytochrome c3 CLZ PF16526.5 GBG66382.1 - 2.3 8.6 8.2 0.17 12.3 0.6 2.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RVT_1 PF00078.27 GBG66383.1 - 2.7e-17 63.1 0.0 3.7e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG66383.1 - 2.9e-07 31.1 0.0 5.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66383.1 - 8.5e-07 29.5 0.0 1.6e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG66383.1 - 1e-06 28.5 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66383.1 - 2.1e-05 24.3 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG66384.1 - 1.1e-05 25.6 13.4 0.012 15.8 0.2 5.1 2 1 1 4 4 4 2 Retrotransposon gag protein SlyX PF04102.12 GBG66384.1 - 0.0012 19.4 15.0 0.21 12.2 0.3 3.7 3 0 0 3 3 3 2 SlyX FlxA PF14282.6 GBG66384.1 - 0.018 15.0 0.9 0.018 15.0 0.9 3.5 4 0 0 4 4 4 0 FlxA-like protein APG6_N PF17675.1 GBG66384.1 - 0.036 14.6 0.0 0.036 14.6 0.0 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF16 PF01519.16 GBG66384.1 - 1.9 9.0 4.7 2.9 8.4 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function DUF16 DUF3037 PF11236.8 GBG66384.1 - 4.8 7.6 7.5 32 5.0 2.6 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) RT_RNaseH PF17917.1 GBG66385.1 - 5.7e-29 100.5 0.1 1.4e-28 99.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66385.1 - 6.9e-28 96.6 0.0 1.8e-27 95.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66385.1 - 6.7e-21 74.8 0.0 1.4e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66385.1 - 2.4e-16 59.6 0.5 5.7e-16 58.4 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG66385.1 - 0.0017 18.6 0.1 0.0055 16.9 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG66385.1 - 0.045 13.4 0.0 0.045 13.4 0.0 2.8 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase IclR PF01614.18 GBG66385.1 - 1.2 8.9 5.7 1.3 8.8 3.6 2.1 2 0 0 2 2 2 0 Bacterial transcriptional regulator Bromo_TP_like PF17027.5 GBG66385.1 - 2.1 8.5 5.6 11 6.2 0.9 3.4 4 0 0 4 4 4 0 Histone-fold protein Myb_DNA-bind_4 PF13837.6 GBG66387.1 - 1.3e-08 35.1 0.5 2.3e-08 34.3 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG66387.1 - 0.015 15.3 0.9 0.031 14.3 0.9 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG66388.1 - 3.3e-06 27.0 0.0 6.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG66388.1 - 0.022 14.5 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region PPI_Ypi1 PF07491.11 GBG66388.1 - 0.51 10.2 1.9 6.4 6.7 0.3 2.7 2 0 0 2 2 2 0 Protein phosphatase inhibitor RR_TM4-6 PF06459.12 GBG66389.1 - 0.83 9.4 16.3 0.98 9.2 16.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 GBG66389.1 - 4 6.8 12.4 4.2 6.7 12.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nop14 PF04147.12 GBG66389.1 - 4.1 5.5 31.8 4.7 5.3 31.8 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG66389.1 - 9.2 4.9 14.3 10 4.8 14.3 1.0 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG66390.1 - 3.2e-29 102.0 0.2 1.3e-28 100.1 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66390.1 - 6.7e-22 77.4 0.0 1.4e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66390.1 - 1.6e-20 73.3 0.0 2.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG66390.1 - 2.3e-07 30.6 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG66390.1 - 1.2e-06 29.1 0.0 2.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66390.1 - 0.00025 21.6 0.0 0.00062 20.3 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG66390.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease APG17 PF04108.12 GBG66390.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 RVT_1 PF00078.27 GBG66391.1 - 1.7e-19 70.2 0.0 9.9e-14 51.4 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Hormone_3 PF00159.18 GBG66391.1 - 0.39 10.8 0.2 0.39 10.8 0.2 2.8 2 0 0 2 2 2 0 Pancreatic hormone peptide rve PF00665.26 GBG66392.1 - 3.7e-16 59.4 0.0 1.2e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG66392.1 - 1e-14 54.4 0.2 2.6e-14 53.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG66392.1 - 0.0032 17.7 0.1 0.0074 16.5 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Lamprin PF06403.11 GBG66392.1 - 1.4 8.9 5.5 3.4 7.6 5.5 1.6 1 0 0 1 1 1 0 Lamprin UPF0240 PF06784.11 GBG66397.1 - 0.14 12.2 0.3 0.24 11.4 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) RT_RNaseH PF17917.1 GBG66398.1 - 4.7e-60 200.4 0.3 6.1e-29 100.4 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66398.1 - 9.1e-60 198.9 0.0 6.6e-29 99.9 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66398.1 - 3.1e-17 62.4 0.9 7.2e-17 61.2 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_4 PF13359.6 GBG66398.1 - 9.4e-13 48.1 0.0 2.3e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG66398.1 - 1.7e-11 44.1 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plant_tran PF04827.14 GBG66398.1 - 0.00011 21.9 0.0 0.00032 20.3 0.0 1.7 1 0 0 1 1 1 1 Plant transposon protein zf-H2C2 PF09337.10 GBG66398.1 - 0.00059 20.0 0.1 0.0015 18.7 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger SH3_16 PF18348.1 GBG66398.1 - 0.089 12.6 0.0 22 4.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF1962 PF09227.10 GBG66398.1 - 5.2 7.5 7.4 15 6.0 3.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1962) VIR_N PF15912.5 GBG66399.1 - 0.032 13.8 0.8 0.054 13.1 0.8 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Tub_N PF16322.5 GBG66399.1 - 0.11 12.9 2.6 0.19 12.1 2.6 1.4 1 0 0 1 1 1 0 Tubby N-terminal RVT_1 PF00078.27 GBG66400.1 - 1.4e-06 28.0 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG66400.1 - 0.083 13.0 0.5 0.15 12.2 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle HALZ PF02183.18 GBG66400.1 - 0.21 11.8 4.6 0.59 10.4 4.6 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper Rx_N PF18052.1 GBG66400.1 - 0.98 9.7 10.4 2.8 8.3 0.0 3.6 3 0 0 3 3 3 0 Rx N-terminal domain COMP PF11598.8 GBG66400.1 - 1.1 9.8 5.0 3.5 8.2 5.0 1.9 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein DUF812 PF05667.11 GBG66400.1 - 2.5 6.9 35.5 4.7 6.0 35.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Prominin PF05478.11 GBG66400.1 - 7.7 4.3 11.8 0.022 12.8 1.9 1.6 2 0 0 2 2 2 0 Prominin RT_RNaseH_2 PF17919.1 GBG66401.1 - 1.9e-26 92.0 0.0 3.4e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66401.1 - 1.5e-23 83.1 0.0 2.8e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66401.1 - 6.6e-12 45.4 0.1 1.3e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IQ PF00612.27 GBG66402.1 - 0.0012 18.4 0.4 0.0028 17.3 0.4 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif SDA1 PF05285.12 GBG66404.1 - 0.0061 16.0 16.3 0.0063 16.0 16.3 1.1 1 0 0 1 1 1 1 SDA1 RXT2_N PF08595.11 GBG66404.1 - 0.052 13.6 6.8 0.065 13.3 6.8 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4366 PF14283.6 GBG66404.1 - 0.064 13.3 4.8 0.091 12.8 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Nop14 PF04147.12 GBG66404.1 - 0.082 11.1 19.9 0.09 11.0 19.9 1.0 1 0 0 1 1 1 0 Nop14-like family Defensin_RK-1 PF17860.1 GBG66404.1 - 0.11 13.0 0.1 0.2 12.2 0.1 1.3 1 0 0 1 1 1 0 RK-1-like defensin RNA_pol_Rpc4 PF05132.14 GBG66404.1 - 0.12 12.8 4.1 0.17 12.3 4.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPA43_OB PF17875.1 GBG66404.1 - 0.13 12.9 4.3 0.18 12.4 4.3 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RNA_polI_A34 PF08208.11 GBG66404.1 - 0.15 12.1 8.0 0.2 11.8 8.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Zip PF02535.22 GBG66404.1 - 0.17 11.1 1.4 0.18 11.0 1.4 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 GBG66404.1 - 0.22 9.9 18.4 0.26 9.7 18.4 1.0 1 0 0 1 1 1 0 Mpp10 protein Presenilin PF01080.17 GBG66404.1 - 0.26 10.0 0.8 0.29 9.9 0.8 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG66404.1 - 0.36 9.1 13.4 0.39 9.0 13.4 1.0 1 0 0 1 1 1 0 CDC45-like protein AIF_C PF14721.6 GBG66404.1 - 0.44 10.9 1.8 0.62 10.4 1.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.12 GBG66404.1 - 0.82 9.4 9.6 1 9.1 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.10 GBG66404.1 - 1 8.6 15.6 1.2 8.4 15.6 1.1 1 0 0 1 1 1 0 BUD22 DUF4820 PF16091.5 GBG66404.1 - 1.3 8.3 5.0 1.6 8.0 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Tim54 PF11711.8 GBG66404.1 - 1.6 7.4 8.5 1.9 7.2 8.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DNA_pol_phi PF04931.13 GBG66404.1 - 2.5 6.1 30.6 2.9 5.9 30.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 GBG66404.1 - 3.6 7.7 7.4 4.6 7.4 7.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Sigma70_ner PF04546.13 GBG66404.1 - 4.4 7.1 16.7 6.1 6.7 16.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Connexin PF00029.19 GBG66404.1 - 6.2 6.5 4.9 7.8 6.2 4.9 1.1 1 0 0 1 1 1 0 Connexin RPN2_C PF18004.1 GBG66404.1 - 8.8 6.2 14.1 11 5.9 14.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF913 PF06025.12 GBG66404.1 - 9.5 5.1 5.8 12 4.8 5.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF740 PF05340.12 GBG66404.1 - 9.7 4.8 9.2 12 4.6 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Hira PF07569.11 GBG66406.1 - 2.9e-47 161.2 0.0 7e-47 160.0 0.0 1.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 GBG66406.1 - 7.6e-27 93.0 26.6 3e-07 31.0 1.1 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG66406.1 - 1.7e-14 53.9 0.1 0.00022 21.4 0.1 6.3 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG66406.1 - 0.008 14.9 0.1 1.5 7.4 0.1 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GBG66406.1 - 0.015 14.2 0.0 4.2 6.2 0.0 3.7 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Vps16_N PF04841.13 GBG66406.1 - 0.018 13.8 0.0 0.22 10.3 0.0 2.2 2 0 0 2 2 2 0 Vps16, N-terminal region WD40_like PF17005.5 GBG66406.1 - 0.18 11.1 0.0 6.1 6.1 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Asp PF00026.23 GBG66407.1 - 2e-121 405.3 0.0 2.4e-121 405.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SapB_2 PF03489.17 GBG66407.1 - 3.6e-14 52.6 6.4 7.8e-14 51.5 6.4 1.6 1 0 0 1 1 1 1 Saposin-like type B, region 2 TAXi_N PF14543.6 GBG66407.1 - 3.2e-13 50.3 0.5 1.4e-07 32.0 0.0 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal SapB_1 PF05184.15 GBG66407.1 - 5.5e-12 45.5 0.5 1.3e-11 44.3 0.5 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 1 TAXi_C PF14541.6 GBG66407.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal C_LFY_FLO PF17538.2 GBG66408.1 - 1.2e-53 181.1 1.6 2.2e-53 180.2 1.6 1.4 1 0 0 1 1 1 1 DNA Binding Domain (C-terminal) Leafy/Floricaula SAM_LFY PF01698.16 GBG66408.1 - 7.3e-31 106.0 0.5 1.3e-30 105.2 0.5 1.4 1 0 0 1 1 1 1 Floricaula / Leafy protein SAM domain RT_RNaseH_2 PF17919.1 GBG66409.1 - 5.9e-20 71.2 0.0 1.3e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66409.1 - 8.1e-20 71.1 0.0 1.6e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66409.1 - 1.3e-14 54.4 0.0 2.8e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG66409.1 - 2.3e-10 40.4 0.1 2.3e-10 40.4 0.1 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG66409.1 - 6.9e-06 26.5 0.0 1.7e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66409.1 - 7.1e-06 26.6 0.1 1.6e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG66409.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-FCS PF06467.14 GBG66409.1 - 0.24 11.4 0.4 0.56 10.2 0.4 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CCHC PF00098.23 GBG66409.1 - 1.7 8.8 3.4 4.8 7.4 3.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Asp PF00026.23 GBG66410.1 - 2.7e-98 329.3 0.1 3.4e-98 329.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SapB_2 PF03489.17 GBG66410.1 - 3e-14 52.8 6.4 6.6e-14 51.7 6.4 1.6 1 0 0 1 1 1 1 Saposin-like type B, region 2 TAXi_N PF14543.6 GBG66410.1 - 9.2e-14 52.1 0.3 2.2e-11 44.3 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal SapB_1 PF05184.15 GBG66410.1 - 4.4e-12 45.8 0.5 1.1e-11 44.5 0.5 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 1 YqfQ PF14181.6 GBG66410.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 YqfQ-like protein Dehydrin PF00257.19 GBG66410.1 - 0.74 10.4 2.4 5.4 7.5 0.2 2.4 2 0 0 2 2 2 0 Dehydrin DUF2615 PF11027.8 GBG66411.1 - 0.11 12.6 0.8 5.4 7.2 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF4094 PF13334.6 GBG66416.1 - 0.15 12.4 2.3 0.36 11.3 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) CorA PF01544.18 GBG66416.1 - 0.16 11.3 3.2 0.25 10.6 3.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SPAM PF02090.15 GBG66416.1 - 0.96 9.3 12.8 0.086 12.6 7.5 2.0 2 1 1 3 3 3 0 Salmonella surface presentation of antigen gene type M protein Fez1 PF06818.15 GBG66416.1 - 6.1 7.3 16.3 1.9 8.9 9.6 2.5 2 1 0 2 2 2 0 Fez1 Nop14 PF04147.12 GBG66418.1 - 1.8 6.7 8.6 2.2 6.4 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family Hep_59 PF07052.11 GBG66420.1 - 0.00033 21.4 10.3 0.00033 21.4 10.3 2.0 1 1 1 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF1943 PF09172.11 GBG66420.1 - 0.01 15.1 5.1 0.015 14.6 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF2058 PF09831.9 GBG66420.1 - 0.59 10.3 16.4 0.85 9.7 14.8 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) VIT1 PF01988.19 GBG66420.1 - 3 7.7 6.2 16 5.2 3.9 2.2 2 0 0 2 2 2 0 VIT family RT_RNaseH_2 PF17919.1 GBG66421.1 - 2.3e-28 98.2 0.0 5.7e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66421.1 - 6.4e-22 78.2 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66421.1 - 1.2e-17 63.7 0.4 2.4e-17 62.8 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG66421.1 - 1.2e-13 51.3 0.2 5.7e-13 49.1 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66421.1 - 9.8e-12 45.1 0.1 6.5e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain CENP-Q PF13094.6 GBG66421.1 - 0.029 14.6 2.5 0.062 13.5 2.5 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2884 PF11101.8 GBG66421.1 - 0.15 11.6 0.7 0.29 10.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) zf-CCHC PF00098.23 GBG66422.1 - 2.6e-05 24.1 2.0 5e-05 23.2 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG66422.1 - 0.094 12.5 0.5 0.094 12.5 0.5 1.8 2 0 0 2 2 2 0 Zinc knuckle SH3-WW_linker PF16618.5 GBG66422.1 - 0.27 11.7 4.4 0.19 12.2 0.9 2.1 2 0 0 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 RIO1 PF01163.22 GBG66423.1 - 2.8e-57 193.4 0.1 2.8e-57 193.4 0.1 1.9 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 GBG66423.1 - 0.0007 18.5 0.0 0.0007 18.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GBG66423.1 - 0.0051 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFMR_assoc PF16596.5 GBG66423.1 - 1.2 9.6 10.1 2.4 8.6 10.1 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR PfkB PF00294.24 GBG66425.1 - 3.1e-40 138.4 4.2 1.1e-21 77.5 1.7 2.1 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Pyr_redox_2 PF07992.14 GBG66426.1 - 0.16 11.2 0.3 3.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rep_fac_C PF08542.11 GBG66429.1 - 5.6e-16 58.7 0.0 7.2e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 GBG66433.1 - 8.5e-16 58.6 0.0 1.2e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GBG66433.1 - 1.7e-13 50.7 0.0 3.4e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 GBG66433.1 - 8.3e-10 38.9 0.0 2.4e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 GBG66433.1 - 2.3e-06 27.9 0.3 0.026 14.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 GBG66433.1 - 4.2e-06 26.8 0.0 2.8e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 GBG66433.1 - 1.7e-05 24.8 0.0 3e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 GBG66433.1 - 2.2e-05 24.7 0.0 4.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA C-terminal domain AAA_7 PF12775.7 GBG66433.1 - 5e-05 22.9 0.0 7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 GBG66433.1 - 5.2e-05 23.7 0.0 0.00022 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 GBG66433.1 - 5.4e-05 23.2 0.0 8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GBG66433.1 - 0.0007 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 GBG66433.1 - 0.0007 19.4 0.0 0.0017 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GBG66433.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG66433.1 - 0.0028 18.0 0.1 0.03 14.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 GBG66433.1 - 0.0028 17.5 0.0 0.006 16.5 0.0 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GBG66433.1 - 0.0029 17.6 0.0 0.12 12.4 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG66433.1 - 0.0056 16.5 0.2 0.059 13.1 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF815 PF05673.13 GBG66433.1 - 0.0084 15.3 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 GBG66433.1 - 0.028 15.0 0.0 0.12 12.9 0.0 1.8 1 1 0 2 2 2 0 AAA domain TniB PF05621.11 GBG66433.1 - 0.033 13.6 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 GBG66433.1 - 0.065 12.7 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 GBG66433.1 - 0.067 12.6 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GBG66433.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.6 1 1 0 1 1 1 0 RNA helicase TIP49 PF06068.13 GBG66433.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 GBG66433.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 GBG66433.1 - 0.19 10.9 0.1 1.7 7.8 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arginosuc_synth PF00764.19 GBG66434.1 - 6.6e-155 516.2 0.0 7.9e-155 515.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase DUF2795 PF11387.8 GBG66434.1 - 0.071 13.3 0.3 4.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) MMADHC PF10229.9 GBG66435.1 - 6.7e-24 85.1 0.0 1e-23 84.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein SET PF00856.28 GBG66436.1 - 1e-13 52.0 0.0 2e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 GBG66436.1 - 3.5e-06 27.7 0.0 7.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Pterin_bind PF00809.22 GBG66437.1 - 1.4e-78 264.0 0.0 2.4e-78 263.2 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 GBG66437.1 - 1.5e-33 115.7 0.0 2.7e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) TPR_12 PF13424.6 GBG66438.1 - 1e-20 73.8 17.9 4.4e-06 26.9 0.1 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 GBG66438.1 - 3e-16 58.5 11.7 0.0019 18.0 0.5 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GBG66438.1 - 2.3e-14 52.3 11.8 0.0024 17.8 0.2 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GBG66438.1 - 1.5e-10 40.4 13.9 0.016 15.4 0.0 6.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 GBG66438.1 - 1.6e-10 40.3 11.0 0.00026 20.8 0.2 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat ANAPC5 PF12862.7 GBG66438.1 - 1.5e-07 31.3 0.5 1.2e-05 25.3 1.5 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 GBG66438.1 - 1e-05 25.1 4.7 0.00047 19.6 0.2 3.2 3 1 0 3 3 3 2 MalT-like TPR region TPR_10 PF13374.6 GBG66438.1 - 7.1e-05 22.5 13.1 1.3 9.0 0.4 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 GBG66438.1 - 0.00024 21.3 2.0 0.58 10.7 0.4 4.4 3 1 0 3 3 3 1 Tetratricopeptide repeat GATase PF00117.28 GBG66438.1 - 0.0013 18.6 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I TPR_16 PF13432.6 GBG66438.1 - 0.023 15.3 8.7 8 7.2 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GBG66438.1 - 0.06 12.8 3.7 0.44 10.0 0.2 2.7 2 0 0 2 2 2 0 SHNi-TPR TPR_14 PF13428.6 GBG66438.1 - 0.18 12.7 10.2 56 5.0 0.0 5.9 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 GBG66438.1 - 0.54 10.0 8.0 19 5.1 0.1 5.1 5 1 1 6 6 6 0 TPR repeat SE PF08491.10 GBG66439.1 - 3e-110 367.6 0.0 4.1e-110 367.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 GBG66439.1 - 6.5e-18 65.1 0.0 9e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GBG66439.1 - 2.3e-08 34.0 0.0 0.0005 19.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG66439.1 - 8.7e-07 28.4 1.0 7.7e-05 21.9 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GBG66439.1 - 1.8e-05 24.8 0.4 4e-05 23.8 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GBG66439.1 - 2.9e-05 23.3 0.1 0.00026 20.2 0.1 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GBG66439.1 - 0.00078 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GBG66439.1 - 0.00081 18.8 0.4 0.0021 17.5 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GBG66439.1 - 0.0038 16.0 0.0 0.0058 15.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 GBG66439.1 - 0.0053 16.0 0.1 0.0053 16.0 0.1 1.6 2 0 0 2 2 1 1 Thi4 family Lycopene_cycl PF05834.12 GBG66439.1 - 0.007 15.5 0.1 0.016 14.3 0.1 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 GBG66439.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 GBG66439.1 - 0.16 10.8 0.8 4 6.2 0.1 2.2 1 1 0 2 2 2 0 Tryptophan halogenase Cnd1 PF12717.7 GBG66440.1 - 3.3e-06 27.2 2.3 0.14 12.2 0.0 4.1 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GBG66440.1 - 8.5e-06 25.6 12.8 0.66 10.4 0.0 8.0 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 GBG66440.1 - 0.00053 20.3 7.5 0.33 11.3 0.1 4.7 4 1 0 4 4 4 2 HEAT repeats HAD_2 PF13419.6 GBG66440.1 - 0.16 12.1 1.2 16 5.6 0.6 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Lambda_CIII PF02061.16 GBG66441.1 - 0.52 10.4 2.3 5.7 7.1 0.9 2.7 3 0 0 3 3 3 0 Lambda Phage CIII Corazonin PF17308.2 GBG66441.1 - 3.5 8.0 18.9 0.25 11.7 3.6 2.3 2 0 0 2 2 2 0 Pro-corazonin Pro_isomerase PF00160.21 GBG66442.1 - 6.7e-41 140.2 0.0 1.7e-40 138.9 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L38e PF01781.18 GBG66443.1 - 1.8e-06 27.9 0.6 2.7e-06 27.4 0.6 1.3 1 0 0 1 1 1 1 Ribosomal L38e protein family Nucleo_P87 PF07267.11 GBG66443.1 - 4.3 6.1 7.5 5.5 5.7 7.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3682 PF12446.8 GBG66443.1 - 6.1 7.3 10.0 9.7 6.7 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF2062 PF09835.9 GBG66444.1 - 5.6e-15 55.5 6.2 7.9e-15 55.0 6.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) Flavin_Reduct PF01613.18 GBG66444.1 - 0.81 9.7 3.0 1.5 8.8 3.0 1.4 1 0 0 1 1 1 0 Flavin reductase like domain UDPGP PF01704.18 GBG66446.1 - 0.081 11.5 0.0 3.4 6.2 0.0 2.0 2 0 0 2 2 2 0 UTP--glucose-1-phosphate uridylyltransferase TRAP-gamma PF07074.12 GBG66447.1 - 0.086 12.4 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) zf-CCHC PF00098.23 GBG66448.1 - 0.0016 18.4 0.7 0.0027 17.7 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG66448.1 - 0.0032 17.2 1.8 0.0058 16.4 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle ArAE_2_N PF10337.9 GBG66448.1 - 0.43 9.6 2.5 0.66 8.9 2.5 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal SOBP PF15279.6 GBG66448.1 - 6.8 7.2 11.5 12 6.4 11.1 1.5 1 1 0 1 1 1 0 Sine oculis-binding protein HemY_N PF07219.13 GBG66449.1 - 0.18 12.0 1.5 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 HemY protein N-terminus Prefoldin_2 PF01920.20 GBG66450.1 - 0.017 15.1 0.3 0.017 15.1 0.3 2.8 2 0 0 2 2 2 0 Prefoldin subunit LPP20 PF02169.16 GBG66450.1 - 0.047 14.0 0.3 0.14 12.5 0.3 1.8 1 0 0 1 1 1 0 LPP20 lipoprotein FTO_CTD PF12934.7 GBG66450.1 - 0.71 9.6 5.7 0.24 11.1 2.4 1.9 2 0 0 2 2 2 0 FTO C-terminal domain OmpH PF03938.14 GBG66450.1 - 2.4 8.5 20.7 1.3 9.3 7.4 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) SPT16 PF08644.11 GBG66450.1 - 2.5 8.3 7.8 5.2 7.2 0.1 2.9 2 1 1 3 3 3 0 FACT complex subunit (SPT16/CDC68) DUF5320 PF17253.2 GBG66450.1 - 3.8 8.6 8.5 2.9 9.0 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Redoxin PF08534.10 GBG66452.1 - 9.3e-16 57.9 0.1 5.3e-15 55.4 0.0 1.8 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 GBG66452.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Integrase_H2C2 PF17921.1 GBG66453.1 - 3.2e-18 65.6 1.0 7.1e-18 64.5 1.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG66453.1 - 5e-05 23.4 0.4 0.00014 22.0 0.1 1.9 2 0 0 2 2 2 1 H2C2 zinc finger rve PF00665.26 GBG66453.1 - 0.016 15.4 0.3 0.058 13.6 0.1 1.9 2 0 0 2 2 2 0 Integrase core domain FtsK_4TM PF13491.6 GBG66454.1 - 0.13 11.9 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE RT_RNaseH_2 PF17919.1 GBG66455.1 - 2.8e-29 101.1 0.1 4.8e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66455.1 - 3.8e-22 78.6 0.0 7.6e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66455.1 - 9.3e-21 74.4 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gemini_AC4_5 PF04807.12 GBG66455.1 - 0.12 12.1 0.3 0.87 9.3 0.1 2.3 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region Retrotrans_gag PF03732.17 GBG66456.1 - 0.0067 16.7 1.2 0.02 15.1 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Lipin_mid PF16876.5 GBG66456.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain COG6 PF06419.11 GBG66458.1 - 1.7e-62 211.6 0.0 2.2e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Nsp1_C PF05064.13 GBG66458.1 - 0.064 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region Sec34 PF04136.15 GBG66458.1 - 0.066 13.1 0.3 0.13 12.1 0.2 1.5 1 1 0 1 1 1 0 Sec34-like family DUF2656 PF10847.8 GBG66458.1 - 0.086 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) DUF1664 PF07889.12 GBG66458.1 - 0.091 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 GBG66459.1 - 0.0022 18.2 0.1 0.0022 18.2 0.1 3.6 4 0 0 4 4 4 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG66459.1 - 0.01 15.6 0.7 0.032 14.0 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG66459.1 - 0.092 12.1 9.9 0.19 11.0 9.9 1.5 1 0 0 1 1 1 0 FAM76 protein TAF4 PF05236.14 GBG66459.1 - 1.2 8.8 15.7 0.11 12.2 10.6 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family APG6_N PF17675.1 GBG66459.1 - 6.3 7.3 26.2 0.43 11.1 1.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region COG6 PF06419.11 GBG66460.1 - 3.5e-117 392.2 0.0 4.2e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 GPAT_N PF14829.6 GBG66460.1 - 0.11 12.5 0.1 11 6.2 0.0 3.0 3 0 0 3 3 3 0 Glycerol-3-phosphate acyltransferase N-terminal DUF4336 PF14234.6 GBG66461.1 - 9.5e-104 347.0 0.4 1.1e-80 271.3 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) zf-CCHC PF00098.23 GBG66462.1 - 9.1e-07 28.7 4.7 1.7e-06 27.8 4.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG66462.1 - 0.0074 16.2 1.8 0.022 14.7 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG66462.1 - 0.33 10.7 1.1 0.64 9.8 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle ABC1 PF03109.16 GBG66463.1 - 2.3e-29 101.9 0.0 4.1e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GBG66463.1 - 6.7e-06 26.2 0.3 2.8e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 GBG66463.1 - 0.00088 18.7 0.0 0.004 16.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain RVT_1 PF00078.27 GBG66465.1 - 2.8e-31 108.7 0.1 4.3e-31 108.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66465.1 - 1.8e-19 69.6 0.0 2.5e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG66465.1 - 1.3e-11 44.3 0.0 3e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG66465.1 - 1.1e-07 32.1 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG66465.1 - 0.086 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease LRR_6 PF13516.6 GBG66466.1 - 9e-07 28.5 1.3 4.2 7.7 0.0 6.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 GBG66466.1 - 1.2e-05 25.5 6.9 3.3 8.3 0.0 6.4 5 2 3 8 8 8 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 GBG66466.1 - 0.00028 20.7 7.0 0.00029 20.7 4.2 2.5 2 1 1 3 3 3 1 F-box-like F-box PF00646.33 GBG66466.1 - 0.44 10.5 4.4 0.61 10.0 2.1 2.6 2 0 0 2 2 2 0 F-box domain RRM_1 PF00076.22 GBG66468.1 - 1.4e-18 66.4 0.0 2.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pectinesterase PF01095.19 GBG66471.1 - 2.1e-68 230.3 2.6 1.3e-67 227.6 2.6 1.9 1 1 0 1 1 1 1 Pectinesterase GP67 PF17634.2 GBG66472.1 - 0.067 13.6 0.1 0.067 13.6 0.1 2.8 3 0 0 3 3 3 0 Gene product 67 gag-asp_proteas PF13975.6 GBG66473.1 - 1.3e-05 25.7 0.1 3.5e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66473.1 - 0.00024 21.7 0.1 0.00072 20.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG66473.1 - 0.005 16.6 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66473.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG66473.1 - 0.025 14.2 0.3 0.05 13.3 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like cNMP_binding PF00027.29 GBG66473.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain zf-CCHC PF00098.23 GBG66473.1 - 0.42 10.8 1.9 0.77 9.9 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle ECH_1 PF00378.20 GBG66474.1 - 4e-49 167.2 0.0 8.6e-49 166.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GBG66474.1 - 2.2e-20 73.4 0.0 5.2e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Myb_DNA-bind_4 PF13837.6 GBG66474.1 - 0.00028 21.2 1.6 0.00028 21.2 1.6 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain AAA_23 PF13476.6 GBG66474.1 - 0.054 14.0 0.6 0.11 13.0 0.6 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GBG66474.1 - 0.11 12.3 1.9 0.21 11.4 1.9 1.3 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 GBG66474.1 - 0.41 9.9 4.1 0.75 9.1 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3552 PF12072.8 GBG66474.1 - 1.9 7.9 11.9 4.7 6.6 11.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Thioredoxin PF00085.20 GBG66475.1 - 2e-07 30.9 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 GBG66475.1 - 0.087 12.6 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 GBG66475.1 - 0.097 13.0 0.1 0.68 10.3 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like DUF872 PF05915.12 GBG66476.1 - 6.7e-25 87.5 0.3 7.1e-25 87.4 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) RT_RNaseH PF17917.1 GBG66477.1 - 6.4e-23 81.1 0.0 1.6e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66477.1 - 2.2e-20 72.5 0.0 5.1e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG66477.1 - 1.9e-07 31.5 0.0 4.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66477.1 - 5.9e-05 23.6 0.0 0.00016 22.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG66477.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Rota_NS53 PF00981.17 GBG66477.1 - 0.028 13.3 1.0 0.043 12.7 1.0 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) RPW8 PF05659.11 GBG66477.1 - 0.19 11.4 7.0 10 5.8 1.1 3.6 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Bap31_Bap29_C PF18035.1 GBG66477.1 - 0.25 11.4 4.7 1 9.4 4.7 2.1 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1664 PF07889.12 GBG66477.1 - 0.7 9.9 7.4 1.2 9.2 3.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) USP8_interact PF08941.10 GBG66477.1 - 1.8 8.4 6.7 1.5 8.6 3.3 2.3 2 0 0 2 2 2 0 USP8 interacting DJ-1_PfpI PF01965.24 GBG66478.1 - 2.9e-12 46.7 0.3 5.5e-12 45.8 0.3 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family RVT_1 PF00078.27 GBG66479.1 - 2.9e-33 115.3 0.0 6.9e-33 114.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66479.1 - 3.5e-31 107.2 0.3 9.2e-31 105.8 0.3 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66479.1 - 3.7e-19 69.0 0.1 1.1e-18 67.5 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66479.1 - 7.6e-14 51.9 0.0 1.9e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG66479.1 - 0.033 14.1 0.2 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Mannitol_dh_C PF08125.13 GBG66479.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain DJ-1_PfpI PF01965.24 GBG66480.1 - 1.1e-54 184.6 0.2 7.6e-47 159.2 0.1 2.1 2 0 0 2 2 2 2 DJ-1/PfpI family DUF3046 PF11248.8 GBG66480.1 - 0.0067 16.8 0.1 14 6.2 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3046) Retrotrans_gag PF03732.17 GBG66481.1 - 0.003 17.8 0.0 0.012 15.9 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG66483.1 - 4.3e-24 85.3 0.0 6.6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Clathrin PF00637.20 GBG66483.1 - 2.2e-13 50.3 0.7 3.3e-12 46.5 0.0 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS rve PF00665.26 GBG66483.1 - 2e-10 40.9 0.1 2.5e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG66483.1 - 2.8e-05 24.1 0.2 6.9e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-RING_2 PF13639.6 GBG66483.1 - 0.0013 19.0 1.3 0.0013 19.0 1.3 2.5 3 0 0 3 3 3 1 Ring finger domain UTP15_C PF09384.10 GBG66483.1 - 0.015 15.0 1.5 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 UTP15 C terminal zf-rbx1 PF12678.7 GBG66483.1 - 0.14 12.4 0.5 0.46 10.8 0.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GBG66483.1 - 0.19 11.8 2.8 0.47 10.5 2.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 GBG66483.1 - 1.5 8.6 14.7 0.0079 15.9 5.8 1.9 2 0 0 2 2 2 0 RING-like zinc finger RVT_1 PF00078.27 GBG66484.1 - 4.2e-24 85.3 0.0 6.8e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Clathrin PF00637.20 GBG66484.1 - 1.7e-14 53.9 0.1 4.1e-13 49.4 0.0 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS rve PF00665.26 GBG66484.1 - 2.1e-10 40.8 0.1 2.6e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG66484.1 - 3e-05 24.0 0.2 7e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-RING_2 PF13639.6 GBG66484.1 - 0.0013 19.0 1.3 0.0013 19.0 1.3 2.4 3 0 0 3 3 3 1 Ring finger domain UTP15_C PF09384.10 GBG66484.1 - 0.014 15.0 1.5 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 UTP15 C terminal zf-rbx1 PF12678.7 GBG66484.1 - 0.15 12.4 0.5 0.47 10.8 0.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Vps39_2 PF10367.9 GBG66484.1 - 0.19 12.2 0.0 11 6.5 0.0 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 GBG66484.1 - 0.2 11.7 2.8 0.48 10.5 2.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 GBG66484.1 - 1.6 8.5 14.7 0.0081 15.9 5.8 1.9 2 0 0 2 2 2 0 RING-like zinc finger Methyltransf_4 PF02390.17 GBG66485.1 - 1.6e-53 180.7 0.0 2.1e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 GBG66485.1 - 0.00044 20.9 0.0 0.00096 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG66485.1 - 0.033 13.7 0.0 0.083 12.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 GBG66485.1 - 0.044 14.4 0.0 0.32 11.7 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 GBG66485.1 - 0.087 13.6 0.0 0.22 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CPP1-like PF11833.8 GBG66486.1 - 1.4e-10 41.1 3.3 5.3e-10 39.3 3.3 1.9 1 1 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DnaJ PF00226.31 GBG66486.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.6 1 1 0 1 1 1 0 DnaJ domain Lys_export PF03956.13 GBG66486.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine exporter LysO Serglycin PF04360.12 GBG66486.1 - 0.087 12.8 4.5 0.26 11.2 4.5 1.8 1 0 0 1 1 1 0 Serglycin GRP PF07172.11 GBG66487.1 - 0.73 10.6 28.3 0.21 12.3 14.0 2.4 2 0 0 2 2 2 0 Glycine rich protein family LRR_4 PF12799.7 GBG66488.1 - 4.3e-09 36.5 7.9 0.00027 21.3 0.2 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG66488.1 - 1.6e-08 34.2 8.2 2.1e-05 24.2 3.8 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 GBG66488.1 - 0.00041 19.9 3.0 0.013 15.1 1.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat PhaP_Bmeg PF09602.10 GBG66488.1 - 0.00057 19.8 0.5 0.00097 19.1 0.5 1.3 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Trans_reg_C PF00486.28 GBG66488.1 - 0.19 11.8 1.7 0.93 9.6 1.0 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Cwf_Cwc_15 PF04889.12 GBG66488.1 - 1.8 8.2 28.4 1.3 8.7 7.8 2.6 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SGP PF17228.2 GBG66488.1 - 4.4 8.2 7.7 6.9 7.6 2.7 2.4 2 0 0 2 2 2 0 Sulphur globule protein LRR_1 PF00560.33 GBG66488.1 - 5.3 8.0 5.7 3.2e+02 2.6 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat CCDC24 PF15669.5 GBG66490.1 - 4.4e-29 101.8 10.4 4.9e-16 59.2 0.9 3.5 3 1 0 3 3 3 2 Coiled-coil domain-containing protein 24 family FA_desaturase PF00487.24 GBG66491.1 - 7.3e-35 121.0 24.5 7.3e-35 121.0 24.5 1.4 1 1 1 2 2 2 2 Fatty acid desaturase Asp_protease_2 PF13650.6 GBG66492.1 - 1.4e-08 35.3 0.0 3.6e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66492.1 - 9.7e-08 32.5 0.2 3e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG66492.1 - 7.5e-07 29.0 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66492.1 - 2.1e-05 24.3 0.0 3.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease PIEZO PF15917.5 GBG66492.1 - 0.96 8.9 3.2 1.7 8.0 3.2 1.3 1 0 0 1 1 1 0 Piezo PAP1 PF08601.10 GBG66492.1 - 2.2 7.9 8.1 3.2 7.4 8.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 CENP-T_N PF16171.5 GBG66493.1 - 6.6 5.5 8.5 8.9 5.1 8.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus PPR_2 PF13041.6 GBG66494.1 - 2e-88 290.5 19.5 3.5e-14 52.7 0.0 14.4 4 3 11 15 15 15 13 PPR repeat family PPR PF01535.20 GBG66494.1 - 6.5e-71 229.8 34.1 1.2e-07 31.5 0.1 16.0 16 0 0 16 16 16 12 PPR repeat PPR_1 PF12854.7 GBG66494.1 - 1.6e-67 222.8 23.8 1.7e-08 34.0 0.0 13.1 13 0 0 13 13 13 12 PPR repeat PPR_3 PF13812.6 GBG66494.1 - 5.3e-66 218.6 0.0 2.9e-14 52.9 0.0 9.6 7 2 2 10 10 10 9 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG66494.1 - 4.9e-28 97.9 0.0 3.6e-08 33.0 0.0 4.9 2 1 1 4 4 4 4 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 GBG66494.1 - 0.06 13.2 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase expression Miga PF10265.9 GBG66494.1 - 0.12 11.3 0.5 0.19 10.6 0.5 1.2 1 0 0 1 1 1 0 Mitoguardin TPR_19 PF14559.6 GBG66494.1 - 0.14 12.7 6.9 8.8 6.9 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Herpes_pp85 PF04637.12 GBG66494.1 - 0.47 8.8 4.8 1.4 7.3 4.8 1.7 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TPR_14 PF13428.6 GBG66494.1 - 2.5 9.1 0.0 2.5 9.1 0.0 9.5 8 3 4 12 12 12 0 Tetratricopeptide repeat zf-RVT PF13966.6 GBG66495.1 - 0.0039 17.9 7.0 0.0039 17.9 7.0 2.8 3 1 0 3 3 3 1 zinc-binding in reverse transcriptase DUF1409 PF07197.12 GBG66495.1 - 0.16 11.9 0.0 6.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) DNA_pol_E_B PF04042.16 GBG66496.1 - 2.1e-43 148.2 0.0 4.4e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 GBG66496.1 - 9.2e-43 145.5 2.1 2.3e-42 144.2 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase delta subunit OB-fold domain RT_RNaseH_2 PF17919.1 GBG66496.1 - 4.8e-31 106.8 0.0 1.2e-30 105.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66496.1 - 3.3e-30 104.4 0.0 8.9e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66496.1 - 6.1e-14 52.1 0.0 1.3e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PriC PF07445.12 GBG66496.1 - 1.8 8.5 16.3 0.32 10.9 3.6 4.0 4 0 0 4 4 4 0 Primosomal replication protein priC Lebercilin PF15619.6 GBG66496.1 - 4.1 7.0 21.7 0.24 11.0 0.8 3.1 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Cnd1 PF12717.7 GBG66498.1 - 3.1e-40 137.9 0.1 4.9e-18 65.7 0.0 3.8 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 GBG66498.1 - 7.4e-27 94.2 0.0 1.7e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 GBG66498.1 - 7.6e-10 38.2 3.9 0.3 11.5 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.20 GBG66498.1 - 3.3e-05 22.7 1.7 0.00025 19.8 0.0 3.0 4 1 0 4 4 4 1 Adaptin N terminal region Cohesin_HEAT PF12765.7 GBG66498.1 - 0.00023 21.4 4.1 0.23 11.8 0.1 4.5 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 GBG66498.1 - 0.0024 17.1 0.5 0.01 15.1 0.2 2.2 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 GBG66498.1 - 0.0024 18.2 2.3 0.41 11.1 0.0 3.9 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 GBG66498.1 - 0.044 14.3 2.3 19 5.9 0.0 5.1 5 1 1 6 6 6 0 HEAT-like repeat DDE_Tnp_4 PF13359.6 GBG66500.1 - 1.9e-17 63.4 0.0 4.3e-17 62.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66500.1 - 1.8e-05 24.4 0.0 0.0035 17.0 0.0 2.3 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66500.1 - 6.9e-05 22.6 0.1 0.002 17.8 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG66501.1 - 2.3e-07 31.1 4.0 5.7e-07 29.8 4.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG66501.1 - 0.14 12.5 2.0 0.29 11.5 2.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PsbQ PF05757.11 GBG66501.1 - 0.92 9.2 8.3 0.63 9.7 2.6 2.3 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Myb_DNA-bind_4 PF13837.6 GBG66507.1 - 3.1e-07 30.7 1.0 6.1e-07 29.7 1.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG66508.1 - 3.4e-06 26.9 3.6 6.5e-06 26.0 3.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG66508.1 - 0.65 9.9 3.8 1 9.3 3.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Hydin_ADK PF17213.3 GBG66508.1 - 4.1 7.7 7.9 7.9 6.7 7.9 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DDE_Tnp_4 PF13359.6 GBG66509.1 - 7.9e-21 74.4 0.0 1.1e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66509.1 - 8.3e-12 45.1 0.0 1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66509.1 - 0.034 13.8 0.9 2.3 7.8 0.2 2.6 2 1 0 2 2 2 0 Transposase DDE domain zf-CCHC PF00098.23 GBG66511.1 - 2e-05 24.5 0.6 3.3e-05 23.8 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG66511.1 - 0.013 15.3 0.6 0.025 14.4 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle V_ATPase_I PF01496.19 GBG66511.1 - 3.2 5.5 4.7 4 5.3 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RT_RNaseH_2 PF17919.1 GBG66513.1 - 2.4e-11 43.6 0.0 7e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66513.1 - 2.8e-07 30.3 0.2 8.9e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG66513.1 - 5.3e-06 27.0 0.0 1.8e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66513.1 - 4.3e-05 24.0 0.0 0.00017 22.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG66513.1 - 0.00023 20.9 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66513.1 - 0.00036 20.3 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG66513.1 - 0.00085 19.6 9.3 0.00096 19.4 0.1 3.9 5 0 0 5 5 5 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG66513.1 - 0.0021 18.3 0.0 0.0055 17.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Use1 PF09753.9 GBG66513.1 - 0.09 12.5 12.8 0.11 12.2 10.9 1.9 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF4288 PF14119.6 GBG66513.1 - 0.27 11.6 4.3 0.85 10.1 4.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) OKR_DC_1 PF01276.20 GBG66513.1 - 0.52 9.0 2.1 3.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain RT_RNaseH_2 PF17919.1 GBG66514.1 - 1e-11 44.7 0.0 2.5e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66514.1 - 1.9e-07 30.8 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG66514.1 - 3.1e-06 27.8 0.0 5.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66514.1 - 2.9e-05 24.5 0.0 4.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG66514.1 - 6.9e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66514.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG66514.1 - 0.00084 19.6 0.0 0.0022 18.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66515.1 - 6.3e-30 104.3 0.1 1.2e-29 103.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66515.1 - 7.9e-18 64.3 0.3 2e-17 63.0 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66515.1 - 8e-11 42.2 0.0 1.9e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG66515.1 - 6.6e-05 23.4 0.0 0.00023 21.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG66515.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG66515.1 - 0.0038 17.0 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG66515.1 - 0.0079 16.8 0.0 0.027 15.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Form-deh_trans PF09163.11 GBG66516.1 - 0.051 13.3 1.7 0.14 12.0 1.7 1.8 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane DUF561 PF04481.12 GBG66517.1 - 2.6 7.1 4.8 4.8 6.3 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) DDE_Tnp_4 PF13359.6 GBG66520.1 - 1.3e-13 50.9 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66520.1 - 9.6e-08 31.9 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66520.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain FAM176 PF14851.6 GBG66521.1 - 0.0011 18.6 0.6 0.0011 18.6 0.6 3.1 1 1 1 2 2 2 1 FAM176 family Orf78 PF06024.12 GBG66521.1 - 0.011 16.0 0.1 0.011 16.0 0.1 1.9 2 0 0 2 2 2 0 Orf78 (ac78) BUD22 PF09073.10 GBG66521.1 - 0.051 12.9 26.4 0.072 12.4 26.4 1.2 1 0 0 1 1 1 0 BUD22 Tmemb_9 PF05434.11 GBG66521.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 TMEM9 SID-1_RNA_chan PF13965.6 GBG66521.1 - 0.3 9.5 0.1 3 6.1 0.0 1.9 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 GBG66521.1 - 0.86 7.4 0.0 0.86 7.4 0.0 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF2615 PF11027.8 GBG66521.1 - 1.1 9.4 5.9 0.26 11.5 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) NPR3 PF03666.13 GBG66521.1 - 4.3 6.0 15.8 0.018 13.9 5.1 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 GBG66521.1 - 5.8 6.2 27.4 2 7.8 1.7 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT UQ_con PF00179.26 GBG66524.1 - 9.4e-20 70.7 0.0 2.1e-19 69.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RT_RNaseH_2 PF17919.1 GBG66525.1 - 3.2e-28 97.7 0.0 1e-27 96.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66525.1 - 5.4e-26 90.9 0.0 1.4e-25 89.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66525.1 - 8.9e-26 90.8 0.1 1.5e-25 90.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG66525.1 - 1.3e-05 25.0 2.9 3.4e-05 23.7 2.9 1.8 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG66525.1 - 0.0012 19.4 0.0 0.0033 18.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG66525.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG66525.1 - 0.017 15.6 0.0 0.046 14.3 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG66525.1 - 0.051 13.4 3.5 0.12 12.2 3.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 GBG66525.1 - 0.079 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease F-box-like PF12937.7 GBG66527.1 - 0.0001 22.1 0.2 0.00024 20.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GBG66527.1 - 0.13 12.7 0.6 8.3 7.0 0.2 3.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) RT_RNaseH PF17917.1 GBG66528.1 - 9.4e-22 77.3 0.0 1.8e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66528.1 - 1.1e-21 76.8 0.0 2.3e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RNA_pol_Rpc4 PF05132.14 GBG66528.1 - 0.56 10.6 7.4 1 9.8 7.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 GBG66528.1 - 0.63 9.4 22.8 0.8 9.1 22.8 1.1 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG66528.1 - 4.4 7.5 16.1 6.3 7.0 16.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated CPSF100_C PF13299.6 GBG66528.1 - 4.8 7.3 8.8 8.4 6.5 8.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal VIR_N PF15912.5 GBG66528.1 - 7.1 6.1 13.2 13 5.2 13.2 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal SMYLE_N PF18615.1 GBG66529.1 - 0.026 14.1 0.1 0.032 13.8 0.1 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RT_RNaseH_2 PF17919.1 GBG66530.1 - 2.2e-34 117.4 0.0 5.4e-34 116.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66530.1 - 8.9e-28 96.7 0.0 1.7e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66530.1 - 4.9e-08 33.2 0.1 1.5e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG66530.1 - 1.1e-07 31.9 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG66530.1 - 1.3e-05 25.3 0.0 2.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Kelch_1 PF01344.25 GBG66531.1 - 6.1e-21 73.7 5.0 9.8e-10 37.9 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GBG66531.1 - 5.3e-19 67.8 0.4 3.6e-07 30.2 0.0 5.7 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.6 GBG66531.1 - 1.5e-07 31.5 0.2 0.03 14.6 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GBG66531.1 - 2.8e-06 27.0 1.2 0.0064 16.4 0.0 4.7 4 0 0 4 4 4 1 Kelch motif F-box PF00646.33 GBG66531.1 - 3.4e-06 26.8 0.1 6.5e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 F-box domain Kelch_5 PF13854.6 GBG66531.1 - 1.2e-05 25.2 2.7 0.00045 20.1 0.0 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 GBG66531.1 - 1.4e-05 25.0 12.4 1.8e-05 24.7 0.0 5.1 6 1 0 6 6 6 1 Galactose oxidase, central domain NHL PF01436.21 GBG66531.1 - 0.13 12.3 0.1 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 NHL repeat Presenilin PF01080.17 GBG66532.1 - 0.31 9.8 5.9 0.41 9.4 5.9 1.1 1 0 0 1 1 1 0 Presenilin Corazonin PF17308.2 GBG66532.1 - 2 8.8 27.9 14 6.1 9.4 2.9 3 0 0 3 3 3 0 Pro-corazonin TFIIE-A_C PF11521.8 GBG66532.1 - 2.5 8.5 13.1 0.5 10.7 3.4 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Methyltransf_12 PF08242.12 GBG66532.1 - 2.7 8.8 13.5 1.1 10.1 0.8 2.7 2 1 0 2 2 2 0 Methyltransferase domain DUF659 PF04937.15 GBG66535.1 - 8.9e-17 61.4 0.0 1.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG66536.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein LIM_bind PF01803.16 GBG66536.1 - 0.23 10.9 1.7 3.1 7.3 0.0 2.5 3 0 0 3 3 3 0 LIM-domain binding protein Novirhabdo_Nv PF05554.11 GBG66539.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein Fasciclin PF02469.22 GBG66542.1 - 2.5e-20 73.0 0.0 3.1e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain RT_RNaseH PF17917.1 GBG66543.1 - 2.2e-25 89.0 0.0 3.7e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66543.1 - 1.8e-24 85.6 0.0 3.3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66543.1 - 1.6e-16 60.1 0.0 4.5e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG66543.1 - 6.7e-15 55.2 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG66544.1 - 0.031 14.3 1.3 0.031 14.3 1.3 2.1 2 0 0 2 2 2 0 Zinc knuckle RNA_pol_Rpc4 PF05132.14 GBG66544.1 - 1.1 9.7 11.4 1 9.8 4.9 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Spem1 PF15670.5 GBG66544.1 - 1.2 8.7 8.3 0.24 10.9 4.1 2.0 2 0 0 2 2 2 0 Spermatid maturation protein 1 RNA_polI_A34 PF08208.11 GBG66544.1 - 1.8 8.6 20.7 0.25 11.4 11.9 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 SID-1_RNA_chan PF13965.6 GBG66546.1 - 2 6.7 3.2 2 6.7 3.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PPP4R2 PF09184.11 GBG66546.1 - 9.9 5.7 30.8 11 5.5 30.3 1.3 1 1 0 1 1 1 0 PPP4R2 EF1_GNE PF00736.19 GBG66547.1 - 8.6e-32 109.2 0.3 1.5e-31 108.5 0.3 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Fasciclin PF02469.22 GBG66548.1 - 2.3e-23 82.8 0.1 2.8e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain U-box PF04564.15 GBG66549.1 - 8.5e-18 64.3 0.0 1.5e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 U-box domain MATH PF00917.26 GBG66549.1 - 4.9e-11 42.8 0.0 8.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 MATH domain zf-NOSIP PF15906.5 GBG66549.1 - 0.013 15.6 0.0 0.033 14.3 0.0 1.7 1 1 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Integrase_H2C2 PF17921.1 GBG66550.1 - 1.1e-18 67.1 0.1 2.1e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66550.1 - 5.8e-14 52.3 0.0 1.3e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG66550.1 - 0.0036 17.5 0.0 0.013 15.7 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF5617 PF18493.1 GBG66551.1 - 0.02 15.0 0.1 0.086 13.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) ERM PF00769.19 GBG66551.1 - 0.023 14.5 8.1 0.034 14.0 8.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GerPC PF10737.9 GBG66551.1 - 0.22 11.6 1.2 1.1 9.2 0.0 2.5 3 1 0 3 3 3 0 Spore germination protein GerPC RVT_1 PF00078.27 GBG66552.1 - 3.2e-34 118.4 0.0 5.6e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66552.1 - 1.2e-28 99.1 0.0 3.6e-28 97.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66552.1 - 5.4e-18 64.8 0.2 1.2e-17 63.7 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG66552.1 - 7e-18 64.8 0.0 2.2e-17 63.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66552.1 - 9.5e-14 51.6 0.0 2.4e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG66552.1 - 4.2e-07 29.8 0.0 9.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG66552.1 - 4.7e-06 27.1 1.7 2e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66552.1 - 0.00048 20.6 1.7 0.0015 19.1 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG66552.1 - 0.0076 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Putative peptidase (DUF1758) AAA_23 PF13476.6 GBG66552.1 - 0.21 12.1 0.5 0.74 10.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain Integrase_H2C2 PF17921.1 GBG66553.1 - 2e-19 69.4 0.0 4e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66553.1 - 4.6e-09 36.5 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG66553.1 - 1.8e-08 34.9 0.0 3.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG66553.1 - 2.2e-08 34.0 0.0 4.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG66553.1 - 1.1e-06 29.1 0.0 2.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG66553.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG66553.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Pkinase_Tyr PF07714.17 GBG66554.1 - 4.9e-27 94.8 0.0 8.5e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG66554.1 - 6.1e-27 94.6 0.0 1e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain rve PF00665.26 GBG66554.1 - 2.4e-09 37.4 0.0 5.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Kinase-like PF14531.6 GBG66554.1 - 5.2e-05 22.7 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GBG66554.1 - 0.00089 19.2 0.2 0.0023 17.9 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Tudor-knot PF11717.8 GBG66554.1 - 0.012 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG66554.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Haspin_kinase PF12330.8 GBG66554.1 - 0.23 10.4 0.0 0.86 8.5 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain RVP PF00077.20 GBG66556.1 - 0.0094 16.3 0.1 0.032 14.6 0.1 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG66556.1 - 0.075 13.6 0.2 0.21 12.1 0.1 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease PapC_C PF13953.6 GBG66557.1 - 0.025 14.4 29.6 2.1 8.2 0.4 7.6 2 2 7 9 9 9 0 PapC C-terminal domain RTA1 PF04479.13 GBG66557.1 - 0.19 11.3 7.5 64 3.1 0.0 5.6 2 2 5 7 7 7 0 RTA1 like protein rve PF00665.26 GBG66558.1 - 1.2e-14 54.5 0.0 3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG66558.1 - 1.3e-07 31.9 0.0 5.4e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66558.1 - 4.1e-07 30.0 0.1 8.4e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG66558.1 - 0.016 14.9 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain DUF4777 PF16007.5 GBG66558.1 - 0.14 12.5 0.4 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) DUF3365 PF11845.8 GBG66560.1 - 0.036 14.4 0.8 0.056 13.8 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) Toprim_N PF08275.11 GBG66561.1 - 0.00012 22.1 6.9 21 5.2 0.1 7.7 1 1 8 10 10 10 1 DNA primase catalytic core, N-terminal domain RTA1 PF04479.13 GBG66561.1 - 0.00058 19.5 15.7 36 3.9 0.0 8.8 1 1 10 12 12 12 0 RTA1 like protein PapC_C PF13953.6 GBG66561.1 - 0.0026 17.6 32.7 2.2 8.2 0.4 9.1 1 1 12 13 13 13 5 PapC C-terminal domain DCR PF14047.6 GBG66561.1 - 0.0052 17.0 9.0 10 6.4 0.1 5.9 2 1 6 8 8 8 1 Dppa2/4 conserved region SH3_19 PF18597.1 GBG66561.1 - 0.092 12.6 46.2 4.7 7.1 0.5 10.8 11 0 0 11 11 11 0 Myosin X N-terminal SH3 domain RT_RNaseH_2 PF17919.1 GBG66562.1 - 7.5e-23 80.5 0.0 3.1e-22 78.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66562.1 - 8.9e-22 77.4 0.0 1.3e-20 73.6 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66562.1 - 0.00042 19.9 0.0 0.00092 18.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG66562.1 - 0.0018 18.5 0.3 0.008 16.4 0.1 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein Coilin_N PF15862.5 GBG66564.1 - 0.36 10.6 3.5 0.42 10.4 3.5 1.1 1 0 0 1 1 1 0 Coilin N-terminus AT_hook PF02178.19 GBG66565.1 - 0.022 14.6 2.4 0.022 14.6 2.4 3.4 3 0 0 3 3 3 0 AT hook motif Dimer_Tnp_hAT PF05699.14 GBG66565.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region F-box PF00646.33 GBG66566.1 - 0.0001 22.1 0.5 0.0001 22.1 0.5 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GBG66566.1 - 0.045 13.7 0.2 0.045 13.7 0.2 1.8 2 0 0 2 2 2 0 F-box-like His_Phos_1 PF00300.22 GBG66567.1 - 3.4e-47 160.7 0.1 3.4e-47 160.7 0.1 2.4 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) Integrase_H2C2 PF17921.1 GBG66567.1 - 1.3e-16 60.4 0.5 3.1e-16 59.2 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG66567.1 - 3.5e-11 43.3 0.1 1.3e-10 41.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66567.1 - 1.6e-06 28.3 0.0 4.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG66567.1 - 2.2e-05 24.4 0.1 0.00012 22.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG66567.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG66567.1 - 0.14 12.4 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG66568.1 - 1.2e-27 96.8 0.1 1.7e-27 96.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66568.1 - 4.3e-23 81.2 0.0 9.5e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66568.1 - 3.5e-13 49.7 0.0 8.3e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66570.1 - 6.8e-31 106.3 0.0 1.3e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66570.1 - 9.2e-31 107.1 0.1 1.7e-30 106.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66570.1 - 6e-28 97.2 0.1 1.1e-27 96.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66570.1 - 7.3e-15 55.2 0.0 1.6e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG66570.1 - 7.2e-14 51.6 0.1 1.1e-12 47.8 0.1 2.7 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG66570.1 - 0.00044 20.4 0.0 0.0019 18.4 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger Rhamno_transf PF11316.8 GBG66570.1 - 0.043 13.2 0.1 0.13 11.7 0.1 1.7 1 1 0 1 1 1 0 Putative rhamnosyl transferase DUF2385 PF09539.10 GBG66570.1 - 0.079 13.5 0.1 1.3 9.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) FANCI_S1-cap PF14674.6 GBG66570.1 - 0.82 9.8 3.6 0.41 10.8 0.4 2.2 2 0 0 2 2 2 0 FANCI solenoid 1 cap Ribosomal_60s PF00428.19 GBG66571.1 - 0.11 13.1 5.0 0.23 12.1 5.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein cNMP_binding PF00027.29 GBG66572.1 - 0.077 13.1 0.6 0.92 9.6 0.0 2.7 3 0 0 3 3 3 0 Cyclic nucleotide-binding domain rve PF00665.26 GBG66573.1 - 6.3e-07 29.6 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG66573.1 - 0.0029 17.4 0.0 0.013 15.3 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG66573.1 - 0.035 14.4 2.0 0.058 13.7 0.2 2.4 2 1 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG66573.1 - 0.048 13.5 0.7 0.085 12.7 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG66574.1 - 8.9e-23 80.2 0.0 1.6e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66574.1 - 1.8e-20 73.2 0.0 5.2e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66574.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG66575.1 - 0.0004 20.9 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66575.1 - 0.00067 20.3 0.0 0.0017 19.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG66575.1 - 0.0099 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Rx_N PF18052.1 GBG66575.1 - 0.02 15.2 0.3 17 5.8 0.0 3.3 3 0 0 3 3 3 0 Rx N-terminal domain Asp_protease PF09668.10 GBG66575.1 - 0.022 14.6 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG66575.1 - 0.028 14.7 0.2 0.18 12.1 0.1 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein DUF1664 PF07889.12 GBG66575.1 - 0.13 12.3 0.5 2.8 8.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RT_RNaseH PF17917.1 GBG66576.1 - 4.5e-25 87.9 0.0 1.3e-24 86.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66576.1 - 6.5e-25 87.1 0.0 1.8e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66576.1 - 1.3e-22 80.4 0.3 4.7e-22 78.6 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG66576.1 - 0.62 10.4 9.5 0.042 14.1 1.2 3.3 4 0 0 4 4 4 0 Retrotransposon gag protein Matrilin_ccoil PF10393.9 GBG66576.1 - 1.6 8.6 7.3 1.3 8.9 0.1 3.4 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1664 PF07889.12 GBG66576.1 - 2.3 8.3 4.7 3.5 7.7 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RT_RNaseH PF17917.1 GBG66577.1 - 3e-21 75.7 0.0 7.7e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66577.1 - 1.7e-18 66.5 0.0 3.9e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66577.1 - 1e-05 25.5 0.2 3.6e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain DDHD PF02862.17 GBG66577.1 - 0.002 18.3 0.8 0.006 16.8 0.8 1.9 1 0 0 1 1 1 1 DDHD domain Asp_protease PF09668.10 GBG66577.1 - 0.0042 16.9 0.0 0.009 15.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG66577.1 - 0.0053 17.0 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG66577.1 - 0.014 15.4 1.2 0.03 14.4 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG66577.1 - 0.015 15.8 0.1 0.24 12.0 0.0 2.8 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease zf-C2H2_10 PF16588.5 GBG66577.1 - 0.041 13.6 1.4 0.082 12.6 1.4 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger RT_RNaseH PF17917.1 GBG66578.1 - 3.6e-30 104.3 0.2 1.7e-29 102.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66578.1 - 3.1e-29 100.9 0.0 9.5e-29 99.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG66579.1 - 0.005 16.9 3.4 0.011 15.8 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG66579.1 - 0.016 15.0 4.5 0.03 14.1 4.5 1.4 1 0 0 1 1 1 0 Zinc knuckle TFIIF_alpha PF05793.12 GBG66580.1 - 1.3e-05 24.1 89.8 1.6e-05 23.7 89.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Retrotrans_gag PF03732.17 GBG66581.1 - 0.068 13.5 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Apt1 PF10351.9 GBG66581.1 - 0.28 10.0 7.4 0.37 9.6 7.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4551 PF15087.6 GBG66581.1 - 2.1 7.1 4.7 2.5 6.9 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) LAP1C PF05609.12 GBG66581.1 - 4.4 6.3 19.3 6.1 5.8 19.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) KBP_C PF12309.8 GBG66581.1 - 8.6 5.8 17.4 0.41 10.1 7.9 2.1 2 0 0 2 2 2 0 KIF-1 binding protein C terminal rve PF00665.26 GBG66582.1 - 1.8e-07 31.3 0.0 4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG66582.1 - 0.00013 21.5 0.0 0.00039 20.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG66582.1 - 0.00025 21.5 0.0 0.00071 20.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66582.1 - 0.0019 18.8 0.1 0.01 16.5 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease rve_3 PF13683.6 GBG66582.1 - 0.0073 16.1 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG66582.1 - 0.011 15.5 0.3 0.027 14.3 0.0 1.7 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 GBG66582.1 - 0.15 12.4 0.1 0.37 11.1 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG66583.1 - 2.4e-27 95.9 0.0 5.5e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GRP PF07172.11 GBG66584.1 - 0.11 13.1 41.5 0.16 12.6 41.5 1.2 1 0 0 1 1 1 0 Glycine rich protein family Integrase_H2C2 PF17921.1 GBG66585.1 - 5.3e-16 58.5 0.1 1.1e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66585.1 - 9.4e-15 54.9 0.0 3.2e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG66586.1 - 1.3e-23 83.7 0.1 2e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2201 PF09967.9 GBG66586.1 - 0.082 13.1 0.1 0.92 9.7 0.0 2.1 2 0 0 2 2 2 0 VWA-like domain (DUF2201) RT_RNaseH_2 PF17919.1 GBG66588.1 - 3.2e-62 206.8 0.0 4.7e-30 103.6 0.0 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66588.1 - 5.6e-53 177.7 0.0 6.9e-25 87.4 0.0 4.6 4 0 0 4 4 4 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66588.1 - 1.1e-24 87.3 0.0 3.1e-16 59.6 0.0 3.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG66588.1 - 3.3e-12 46.8 0.0 0.00028 21.4 0.0 3.3 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66588.1 - 1.5e-09 38.4 0.0 0.0024 18.5 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease rve PF00665.26 GBG66588.1 - 9.4e-09 35.5 0.0 2.6e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG66588.1 - 1e-07 31.8 0.0 0.027 14.3 0.0 3.0 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.20 GBG66588.1 - 3.1e-07 30.6 0.2 0.049 13.9 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease RabGAP-TBC PF00566.18 GBG66588.1 - 0.00043 20.0 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ACT_3 PF10000.9 GBG66588.1 - 0.00076 19.4 2.3 1.6 8.7 0.1 3.9 3 0 0 3 3 3 2 ACT domain Retrotrans_gag PF03732.17 GBG66588.1 - 0.0042 17.3 11.8 1.2 9.5 0.2 4.9 5 0 0 5 5 4 2 Retrotransposon gag protein rve_3 PF13683.6 GBG66588.1 - 0.021 14.6 0.0 0.076 12.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain PapC_C PF13953.6 GBG66588.1 - 8.5 6.3 9.6 53 3.7 0.4 4.5 2 1 3 5 5 5 0 PapC C-terminal domain Retrotrans_gag PF03732.17 GBG66589.1 - 0.00029 21.0 7.1 0.0062 16.8 0.0 3.8 3 1 0 3 3 3 1 Retrotransposon gag protein DUF2781 PF10914.8 GBG66589.1 - 0.081 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) WDCP PF15390.6 GBG66589.1 - 0.28 9.5 2.3 0.38 9.1 2.3 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family FUSC PF04632.12 GBG66589.1 - 4.5 5.7 18.2 7.3 5.0 18.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family RT_RNaseH PF17917.1 GBG66591.1 - 1.8e-41 140.7 0.0 7.9e-20 71.1 0.0 2.2 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66591.1 - 2e-36 124.0 0.0 5.6e-23 80.9 0.0 2.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase DUF2862 PF11061.8 GBG66591.1 - 0.01 15.6 0.1 0.04 13.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) RVT_1 PF00078.27 GBG66592.1 - 4.1e-17 62.4 0.1 8.9e-11 41.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66592.1 - 1.5e-12 47.4 0.0 3.2e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG66592.1 - 1.8e-07 31.7 0.0 3.1e-06 27.7 0.0 2.6 3 0 0 3 3 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66592.1 - 3.7e-06 27.4 0.0 1.1e-05 25.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG66592.1 - 0.00014 21.6 0.0 0.00035 20.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66592.1 - 0.00016 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG66592.1 - 0.0006 20.1 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG66592.1 - 0.01 15.0 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 0 Autophagy protein Apg17 HXXSHH PF07586.11 GBG66592.1 - 0.027 14.1 3.5 1.2 8.6 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Laminin_II PF06009.12 GBG66592.1 - 0.08 13.0 0.7 0.24 11.4 0.2 2.0 2 0 0 2 2 2 0 Laminin Domain II FUSC PF04632.12 GBG66592.1 - 0.25 9.8 4.6 1.4 7.4 3.0 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family CLZ PF16526.5 GBG66592.1 - 0.47 10.8 7.8 0.23 11.9 0.3 3.1 4 0 0 4 4 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-CCHC_2 PF13696.6 GBG66594.1 - 0.0013 18.5 0.6 0.0019 18.0 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG66594.1 - 0.0016 18.6 0.5 0.004 17.4 0.5 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG66594.1 - 0.018 15.1 1.8 0.029 14.4 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG66595.1 - 1.2e-48 163.7 0.0 7.4e-26 90.5 0.2 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66595.1 - 9e-47 157.2 0.0 2.5e-21 75.6 0.0 3.6 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66595.1 - 7.4e-26 90.7 0.0 3.5e-13 49.8 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG66595.1 - 1.9e-13 50.3 0.0 5.1e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG66595.1 - 1.3e-07 31.8 0.2 0.014 15.7 0.0 2.9 2 0 0 2 2 2 2 Retrotransposon gag protein rve_3 PF13683.6 GBG66595.1 - 1e-05 25.2 0.0 0.089 12.6 0.0 3.1 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG66595.1 - 0.00058 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG66595.1 - 0.039 13.9 2.9 0.04 13.9 0.6 2.1 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG66595.1 - 0.06 13.9 0.0 0.25 11.9 0.0 2.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Fur_reg_FbpB PF13040.6 GBG66595.1 - 2.3 7.9 5.7 4.2 7.0 0.9 2.7 2 0 0 2 2 2 0 Fur-regulated basic protein B zf-CCHC PF00098.23 GBG66595.1 - 3.4 7.9 4.7 9.1 6.6 4.7 1.8 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG66596.1 - 2.5e-25 89.3 0.1 3.6e-25 88.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66596.1 - 9.4e-23 80.1 0.0 2.3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66596.1 - 2.3e-13 50.3 0.0 4.2e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG66596.1 - 0.028 14.2 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG66597.1 - 1.8e-60 204.2 0.1 3.5e-34 118.3 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66597.1 - 5.4e-18 64.9 1.2 1.5e-17 63.4 0.3 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG66597.1 - 2.6e-09 37.3 0.4 1.5e-08 34.9 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG66597.1 - 0.00062 20.0 0.2 0.027 14.7 0.0 3.9 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG66598.1 - 2.7e-23 81.9 0.1 5.8e-23 80.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66598.1 - 7.8e-20 71.3 0.0 1.4e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG66598.1 - 1.1e-15 57.9 0.1 4.5e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG66598.1 - 1.2e-10 41.6 0.0 4.2e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66599.1 - 8.5e-16 57.8 0.7 1.8e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG66599.1 - 7.1e-15 55.3 0.0 2.3e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG66599.1 - 0.11 12.5 2.8 0.28 11.2 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle rve_3 PF13683.6 GBG66599.1 - 0.14 12.0 0.9 0.47 10.3 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain MCU PF04678.13 GBG66599.1 - 0.34 11.0 1.4 0.86 9.7 0.9 1.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter zf-CCHC PF00098.23 GBG66599.1 - 1.3 9.3 4.9 2.7 8.2 4.9 1.6 1 0 0 1 1 1 0 Zinc knuckle OmpH PF03938.14 GBG66600.1 - 6.4 7.1 14.3 19 5.6 14.3 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) LETM1 PF07766.13 GBG66600.1 - 9.8 5.4 8.9 9.7 5.4 7.1 1.8 2 0 0 2 2 2 0 LETM1-like protein RVT_1 PF00078.27 GBG66601.1 - 3.4e-21 75.8 0.0 5.5e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66602.1 - 2e-24 85.5 0.0 4.4e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66602.1 - 5.4e-23 81.3 0.0 1.2e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG66602.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66602.1 - 0.0014 19.1 0.0 0.0032 18.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG66602.1 - 0.0066 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG66602.1 - 0.13 13.0 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG66603.1 - 1.4e-27 95.6 0.0 2.6e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66603.1 - 1.7e-24 86.1 0.1 3e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66603.1 - 5.1e-12 45.8 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DASH_Duo1 PF08651.10 GBG66603.1 - 0.035 13.9 0.5 1.9 8.3 1.2 2.7 2 0 0 2 2 2 0 DASH complex subunit Duo1 Fib_alpha PF08702.10 GBG66603.1 - 2.1 8.5 4.1 1.1 9.4 1.8 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RT_RNaseH_2 PF17919.1 GBG66604.1 - 1.6e-26 92.3 0.0 3e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66604.1 - 2.2e-24 85.8 0.1 4.6e-24 84.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66604.1 - 3.5e-09 36.9 0.2 8e-09 35.7 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain Peptidase_M4_C PF02868.15 GBG66604.1 - 0.022 14.6 0.0 0.055 13.3 0.0 1.6 1 1 1 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain zf-CCHC_3 PF13917.6 GBG66605.1 - 0.0035 17.3 0.7 0.0064 16.4 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG66605.1 - 0.0062 16.8 0.3 0.03 14.6 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein ApoO PF09769.9 GBG66605.1 - 0.1 12.5 2.8 13 5.8 0.1 3.5 2 2 0 2 2 2 0 Apolipoprotein O zf-CCHC PF00098.23 GBG66605.1 - 0.23 11.6 2.9 0.37 10.9 2.9 1.3 1 0 0 1 1 1 0 Zinc knuckle FapA PF03961.13 GBG66606.1 - 2.1 6.9 11.7 4.2 5.9 11.7 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A FapA PF03961.13 GBG66607.1 - 0.75 8.3 13.4 0.85 8.1 13.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF87 PF01935.17 GBG66607.1 - 7.7 6.5 7.7 9.5 6.2 7.7 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain RVT_1 PF00078.27 GBG66608.1 - 2.5e-13 50.1 0.0 4.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66608.1 - 1.5e-12 47.4 0.0 5.1e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66608.1 - 0.019 15.2 0.5 0.076 13.3 0.0 2.4 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG66609.1 - 0.0025 18.1 0.1 0.014 15.7 0.0 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG66609.1 - 0.11 12.3 1.2 0.18 11.6 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG66610.1 - 0.0027 17.3 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG66610.1 - 0.003 17.7 0.0 0.0069 16.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain SDA1 PF05285.12 GBG66610.1 - 0.0081 15.6 8.3 0.014 14.8 8.3 1.4 1 0 0 1 1 1 1 SDA1 TFIIE-A_C PF11521.8 GBG66610.1 - 1.8 8.9 6.3 3.7 7.9 6.3 1.6 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha zf-CCHC PF00098.23 GBG66611.1 - 0.058 13.5 0.5 0.1 12.7 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Nup188 PF10487.9 GBG66611.1 - 4.1 5.2 5.6 5.4 4.8 5.6 1.0 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 Retrotrans_gag PF03732.17 GBG66612.1 - 0.0038 17.5 5.0 0.0042 17.3 0.0 3.2 3 1 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG66612.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease CLZ PF16526.5 GBG66612.1 - 0.18 12.2 4.0 5.2 7.5 1.1 3.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RVT_1 PF00078.27 GBG66613.1 - 3.6e-28 98.6 0.1 5.3e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) B3 PF02362.21 GBG66613.1 - 7.7e-15 54.6 0.0 1.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 B3 DNA binding domain RT_RNaseH_2 PF17919.1 GBG66613.1 - 3.4e-07 30.2 0.0 6.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66614.1 - 3.1e-28 98.8 0.1 4.4e-28 98.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66614.1 - 2.9e-07 30.4 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3826 PF12875.7 GBG66615.1 - 0.012 15.7 2.4 0.015 15.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) TMEM100 PF16311.5 GBG66615.1 - 0.44 10.1 2.6 0.77 9.4 2.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 DUF1690 PF07956.11 GBG66615.1 - 0.75 10.2 9.3 1 9.8 9.3 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) RT_RNaseH_2 PF17919.1 GBG66617.1 - 7.4e-97 317.9 0.0 1e-31 108.9 0.0 4.5 4 0 0 4 4 4 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66617.1 - 3.5e-92 303.7 2.9 1.7e-29 102.2 0.0 4.8 4 0 0 4 4 4 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66617.1 - 1.1e-67 227.8 1.7 2.8e-34 118.6 0.0 3.4 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66617.1 - 1.4e-39 134.0 3.3 7.7e-19 67.6 0.1 3.5 3 0 0 3 3 3 2 Integrase zinc binding domain rve PF00665.26 GBG66617.1 - 8.6e-23 80.8 0.1 2.3e-15 56.8 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG66617.1 - 1.7e-08 34.5 0.1 0.0042 17.3 0.0 3.0 2 0 0 2 2 2 2 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG66617.1 - 0.0086 16.0 0.7 0.025 14.6 0.7 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF1336 PF07059.12 GBG66618.1 - 7.7e-14 52.3 0.0 8.5e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Amastin PF07344.11 GBG66619.1 - 0.0098 15.7 1.8 0.014 15.2 1.8 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF5336 PF17270.2 GBG66619.1 - 0.029 14.0 4.6 0.036 13.7 4.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Pho86 PF11124.8 GBG66619.1 - 0.69 9.3 3.0 0.9 8.9 3.0 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 FAD_binding_3 PF01494.19 GBG66620.1 - 2.1e-13 50.3 0.7 3.9e-11 42.8 0.7 3.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GBG66620.1 - 4.6e-06 26.1 0.0 1.1e-05 24.8 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GBG66620.1 - 3.5e-05 23.0 0.0 0.13 11.3 0.0 2.5 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 GBG66620.1 - 0.00093 18.9 1.2 0.015 14.9 0.3 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GBG66620.1 - 0.0011 18.1 0.3 0.0018 17.4 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 GBG66620.1 - 0.0032 16.2 0.2 0.005 15.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 GBG66620.1 - 0.006 16.8 0.8 0.02 15.1 0.1 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GBG66620.1 - 0.026 13.9 0.6 0.043 13.1 0.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG66620.1 - 0.038 13.1 0.3 0.098 11.7 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 GBG66620.1 - 0.064 12.5 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 GBG66620.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 GBG66620.1 - 0.075 11.9 0.2 2.5 6.9 0.1 2.6 2 1 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 GBG66620.1 - 0.1 13.1 0.2 0.69 10.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 GBG66620.1 - 0.15 11.3 0.4 0.25 10.5 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RVT_1 PF00078.27 GBG66621.1 - 3.9e-42 144.3 0.0 7e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG66621.1 - 8.6e-05 23.2 5.1 8.6e-05 23.2 5.1 3.0 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 GBG66622.1 - 3.5e-42 144.4 0.0 7e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG66622.1 - 8.6e-05 23.2 5.1 8.6e-05 23.2 5.1 3.0 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase CDC45 PF02724.14 GBG66624.1 - 5.3 5.2 8.0 6.2 5.0 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TPR_1 PF00515.28 GBG66625.1 - 1.7e-14 52.9 4.6 9.7e-06 25.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG66625.1 - 4.6e-14 51.3 5.2 0.0013 18.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat FKBP_C PF00254.28 GBG66625.1 - 9.1e-13 48.4 0.0 1.7e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_8 PF13181.6 GBG66625.1 - 3.4e-08 33.1 2.4 0.022 14.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG66625.1 - 4.5e-07 29.4 1.3 0.0057 16.3 0.3 3.2 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 GBG66625.1 - 4.9e-07 30.2 8.3 5.7e-05 23.6 2.3 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG66625.1 - 3.2e-06 27.4 1.1 0.032 14.9 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG66625.1 - 2.6e-05 24.8 7.3 3.1 8.5 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 GBG66625.1 - 0.00018 21.6 0.4 0.00018 21.6 0.4 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG66625.1 - 0.0022 17.9 3.9 0.76 9.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG66625.1 - 0.005 17.1 11.0 0.015 15.6 1.6 3.3 3 1 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG66625.1 - 0.0066 16.7 1.5 0.023 14.9 0.5 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GBG66625.1 - 0.099 13.1 0.1 33 5.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG66625.1 - 0.17 12.8 13.1 7.2 7.7 0.3 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 GBG66625.1 - 0.38 11.1 7.2 0.53 10.6 0.4 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 GBG66625.1 - 2.4 8.6 10.7 0.094 13.2 4.4 2.0 2 1 0 2 2 1 0 Bacterial transcriptional activator domain TPR_21 PF09976.9 GBG66625.1 - 8.4 6.1 7.6 6.4 6.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain PPR_2 PF13041.6 GBG66626.1 - 4.6e-57 190.0 0.1 1.3e-12 47.7 0.0 9.4 5 3 6 11 11 11 7 PPR repeat family PPR PF01535.20 GBG66626.1 - 1.4e-49 162.9 2.4 4.3e-06 26.6 0.0 10.5 10 0 0 10 10 10 8 PPR repeat PPR_1 PF12854.7 GBG66626.1 - 1.9e-47 158.6 5.9 9.1e-09 34.9 0.0 9.4 10 0 0 10 10 10 7 PPR repeat PPR_3 PF13812.6 GBG66626.1 - 8.9e-45 150.6 0.0 2.8e-10 40.1 0.0 6.9 4 2 2 7 7 7 6 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG66626.1 - 1.4e-38 132.5 0.0 4.1e-14 52.4 0.0 3.8 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GBG66626.1 - 5.6e-05 23.6 18.8 9.9 7.3 2.2 8.6 5 3 5 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG66626.1 - 0.24 12.1 7.9 30 5.4 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG66626.1 - 2.1 8.6 4.4 98 3.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG66626.1 - 2.5 8.6 0.0 2.5 8.6 0.0 4.3 4 2 2 6 6 6 0 Tetratricopeptide repeat Integrase_H2C2 PF17921.1 GBG66628.1 - 3.9e-19 68.5 0.2 7e-19 67.7 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66628.1 - 1.7e-12 47.6 0.0 4.6e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG66628.1 - 0.081 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DUF1564 PF07600.11 GBG66628.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) DUF21 PF01595.20 GBG66629.1 - 1.6e-25 89.8 0.4 2.5e-25 89.2 0.4 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GBG66629.1 - 2.7e-07 30.9 3.8 0.021 15.3 0.1 3.7 3 0 0 3 3 3 2 CBS domain DUF659 PF04937.15 GBG66630.1 - 4.5e-10 39.6 0.0 8.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG66631.1 - 9.3e-32 109.0 0.1 8.8e-31 105.9 0.0 2.8 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66631.1 - 3.5e-28 98.0 0.6 2.3e-27 95.3 0.1 2.7 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66631.1 - 1.4e-14 54.2 0.1 2.8e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG66631.1 - 1.2e-07 31.6 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG66631.1 - 1.3e-07 32.1 0.0 4e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66631.1 - 8.3e-06 26.3 0.2 9.1e-05 23.0 0.0 2.9 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG66631.1 - 3.3e-05 24.1 1.6 0.031 14.6 0.1 3.5 4 0 0 4 4 4 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG66631.1 - 0.00029 20.6 0.0 0.0094 15.7 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease DUF21 PF01595.20 GBG66631.1 - 0.0025 17.5 0.0 0.0065 16.2 0.0 1.7 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain AMP-binding_C_2 PF14535.6 GBG66631.1 - 0.059 13.7 1.2 2.5 8.5 0.0 3.3 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain DUF659 PF04937.15 GBG66632.1 - 5e-14 52.4 0.0 9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG66632.1 - 2.1e-05 24.2 0.1 4.7e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CDC45 PF02724.14 GBG66634.1 - 0.00034 19.1 8.7 0.00035 19.0 8.7 1.0 1 0 0 1 1 1 1 CDC45-like protein RR_TM4-6 PF06459.12 GBG66634.1 - 0.11 12.3 5.5 0.17 11.7 5.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC106 PF15794.5 GBG66634.1 - 0.33 10.7 6.1 0.41 10.3 6.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Nop14 PF04147.12 GBG66634.1 - 0.5 8.5 17.3 0.56 8.3 17.3 1.0 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 GBG66634.1 - 0.66 9.3 14.9 0.84 9.0 14.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Paf1 PF03985.13 GBG66634.1 - 0.8 8.6 15.9 1.1 8.2 15.9 1.3 1 0 0 1 1 1 0 Paf1 Apt1 PF10351.9 GBG66634.1 - 0.88 8.3 5.9 1 8.2 5.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 GBG66634.1 - 1.2 7.2 7.1 1.6 6.8 7.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SDA1 PF05285.12 GBG66634.1 - 2.8 7.3 21.4 3.3 7.1 21.4 1.0 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 GBG66634.1 - 3.8 5.9 10.4 4.2 5.8 10.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 GBG66634.1 - 6.6 6.0 19.9 8 5.7 19.9 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 GBG66634.1 - 9.9 5.2 24.2 11 5.0 23.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) TAF4 PF05236.14 GBG66635.1 - 0.01 15.6 12.9 0.01 15.6 12.9 1.5 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Ax_dynein_light PF10211.9 GBG66635.1 - 2.9 7.8 15.0 5.2 7.0 15.0 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain PNK3P PF08645.11 GBG66636.1 - 2.6e-42 144.3 0.0 3.4e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase zf-PARP PF00645.18 GBG66636.1 - 2.8e-14 53.7 0.1 5.7e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Hydrolase_6 PF13344.6 GBG66636.1 - 0.0026 17.8 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GBG66636.1 - 0.018 15.1 0.1 1.1 9.3 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase GRAM PF02893.20 GBG66637.1 - 8.5e-16 57.9 0.0 1.4e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Myb_DNA-bind_4 PF13837.6 GBG66638.1 - 1.5e-05 25.3 1.0 2.7e-05 24.4 1.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG66638.1 - 0.001 19.1 0.8 0.0016 18.5 0.8 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain NTP_transf_9 PF04248.12 GBG66638.1 - 0.11 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF427) BUD22 PF09073.10 GBG66638.1 - 2.5 7.4 30.0 4.7 6.4 30.0 1.5 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG66638.1 - 6.8 6.0 43.4 12 5.2 43.4 1.3 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG66639.1 - 2e-29 102.7 0.0 3.9e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66639.1 - 1.6e-18 66.9 0.3 3.4e-18 65.9 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66639.1 - 2.9e-14 52.9 1.4 1.7e-13 50.4 0.0 3.0 4 0 0 4 4 4 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG66639.1 - 6.8e-10 38.9 0.1 1.5e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66639.1 - 1.5e-08 34.9 0.1 6.5e-08 32.8 0.1 2.1 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG66639.1 - 6.1e-08 32.5 0.0 1.6e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG66639.1 - 0.0013 18.9 0.0 0.0034 17.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG66640.1 - 9e-18 63.5 14.3 1.1e-08 34.8 4.8 2.3 2 0 0 2 2 2 2 Zinc knuckle eIF-4B PF06273.11 GBG66640.1 - 5.2e-08 32.4 1.1 5.2e-08 32.4 1.1 3.9 1 1 1 3 3 3 1 Plant specific eukaryotic initiation factor 4B zf-CCHC_2 PF13696.6 GBG66640.1 - 3.5e-05 23.5 10.2 0.0063 16.3 1.2 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 GBG66640.1 - 0.00015 21.7 7.8 0.054 13.5 1.9 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 GBG66640.1 - 0.026 14.3 4.6 0.72 9.6 0.3 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 GBG66640.1 - 0.027 14.9 1.9 4.8 7.6 0.3 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.6 GBG66640.1 - 0.081 12.7 5.5 2.6 7.8 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG66640.1 - 3.5 7.5 7.8 7.2 6.5 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle STAR_dimer PF16544.5 GBG66641.1 - 9.8e-10 37.9 0.0 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 GBG66641.1 - 1.5e-05 24.8 0.5 2.7e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 KH domain STAR_dimer PF16544.5 GBG66642.1 - 1e-09 37.8 0.0 1.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 GBG66642.1 - 1.4e-05 24.8 0.2 3e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 KH domain BRI3BP PF14965.6 GBG66643.1 - 0.2 11.1 1.7 0.31 10.5 1.7 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DUF659 PF04937.15 GBG66645.1 - 9.1e-35 119.8 0.0 1.5e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG66645.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CDC27 PF09507.10 GBG66645.1 - 0.039 13.3 19.1 0.06 12.7 19.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NR_Repeat PF14046.6 GBG66645.1 - 0.042 14.0 0.4 0.27 11.4 0.5 2.3 2 0 0 2 2 2 0 Nuclear receptor repeat GMC_oxred_C PF05199.13 GBG66645.1 - 0.073 13.6 0.1 0.073 13.6 0.1 2.6 3 0 0 3 3 3 0 GMC oxidoreductase TFIIA PF03153.13 GBG66645.1 - 1.4 8.9 12.4 2.1 8.3 12.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COMPASS-Shg1 PF05205.12 GBG66646.1 - 0.01 16.5 1.0 0.22 12.3 0.1 2.0 1 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1161 PF06649.12 GBG66646.1 - 0.026 14.7 0.1 0.044 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) OCD_Mu_crystall PF02423.15 GBG66646.1 - 0.083 11.8 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family RVT_1 PF00078.27 GBG66647.1 - 1.5e-31 109.7 0.0 2.1e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66647.1 - 1.4e-16 60.4 0.0 4.7e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66647.1 - 7.1e-05 23.0 0.0 0.00073 19.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG66647.1 - 0.013 16.2 0.0 0.035 14.7 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG66647.1 - 0.2 11.4 0.0 0.44 10.4 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Myb_DNA-binding PF00249.31 GBG66648.1 - 3.8e-20 71.8 3.5 1.9e-11 44.0 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG66648.1 - 6.5e-17 61.5 1.8 4.6e-14 52.4 0.1 3.1 2 2 1 3 3 3 2 Myb-like DNA-binding domain SPX PF03105.19 GBG66648.1 - 0.0068 16.4 0.4 0.0068 16.4 0.4 2.3 1 1 1 2 2 2 1 SPX domain SidC_N PF18219.1 GBG66648.1 - 0.088 11.8 4.0 0.13 11.2 4.0 1.1 1 0 0 1 1 1 0 SidC N-terminal domain Glycohydro_20b2 PF14845.6 GBG66648.1 - 0.14 12.8 1.9 0.2 12.3 0.2 2.1 3 0 0 3 3 3 0 beta-acetyl hexosaminidase like DUF4140 PF13600.6 GBG66648.1 - 0.79 10.2 3.0 2.5 8.6 3.0 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) 5_nucleotid PF05761.14 GBG66648.1 - 1 8.2 5.2 1.7 7.4 5.2 1.3 1 0 0 1 1 1 0 5' nucleotidase family O-FucT PF10250.9 GBG66649.1 - 5e-46 157.9 0.1 6.5e-46 157.6 0.1 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Sod_Fe_N PF00081.22 GBG66649.1 - 0.025 15.0 0.3 0.049 14.1 0.3 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Methyltransf_16 PF10294.9 GBG66650.1 - 2.3e-16 60.0 0.6 2.4e-09 37.2 0.1 2.7 3 0 0 3 3 3 2 Lysine methyltransferase FAM86 PF14904.6 GBG66650.1 - 9.5e-06 25.6 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function MTS PF05175.14 GBG66650.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CTNNBL PF08216.11 GBG66651.1 - 5.6e-35 119.6 0.1 1.6e-34 118.2 0.1 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear UNC45-central PF11701.8 GBG66651.1 - 0.0095 15.9 0.2 0.14 12.1 0.2 2.7 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central GRP PF07172.11 GBG66651.1 - 0.023 15.4 16.0 0.72 10.6 11.5 2.5 2 0 0 2 2 2 0 Glycine rich protein family Mo25 PF08569.11 GBG66651.1 - 0.023 14.1 0.4 0.054 12.9 0.4 1.7 1 0 0 1 1 1 0 Mo25-like CobT PF06213.12 GBG66652.1 - 7.4 5.9 53.8 9.7 5.5 53.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PGP_phosphatase PF09419.10 GBG66653.1 - 2.7e-36 124.7 0.0 3.9e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 GBG66653.1 - 2.8e-05 24.1 0.0 7.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 GBG66653.1 - 0.27 11.3 0.0 0.49 10.5 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RVT_1 PF00078.27 GBG66654.1 - 1.9e-37 128.9 0.1 3.4e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG66654.1 - 0.00048 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family E1-E2_ATPase PF00122.20 GBG66655.1 - 1.7e-33 115.7 2.6 1.5e-32 112.6 2.3 2.6 2 0 0 2 2 2 1 E1-E2 ATPase RT_RNaseH_2 PF17919.1 GBG66655.1 - 2.7e-30 104.3 0.0 6e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66655.1 - 6.3e-26 91.3 0.0 1.2e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66655.1 - 7e-23 80.9 0.0 1.8e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Hydrolase PF00702.26 GBG66655.1 - 6.4e-07 29.9 0.0 1.4e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GBG66655.1 - 0.0014 18.7 0.0 0.0042 17.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Retrotrans_gag PF03732.17 GBG66655.1 - 0.026 14.8 1.3 0.36 11.1 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG66656.1 - 1.1e-28 100.3 0.3 2e-28 99.4 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66656.1 - 1e-24 86.8 0.0 2.2e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66656.1 - 4.1e-24 84.5 0.0 1e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66656.1 - 3.6e-15 55.8 0.0 8.6e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG66656.1 - 3.9e-05 23.8 0.1 0.0011 19.2 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein APG17 PF04108.12 GBG66656.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 Cation_ATPase_N PF00690.26 GBG66657.1 - 0.00015 21.4 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus FHA PF00498.26 GBG66658.1 - 4.3e-07 30.2 0.0 1.5e-06 28.5 0.0 2.0 1 0 0 1 1 1 1 FHA domain FHA PF00498.26 GBG66659.1 - 4.4e-07 30.1 0.0 1.4e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 FHA domain TPR_1 PF00515.28 GBG66662.1 - 3.8e-07 29.6 1.5 0.0072 16.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG66662.1 - 1.6e-05 24.6 1.1 0.12 12.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG66662.1 - 0.00077 19.9 0.1 0.0018 18.8 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_21 PF09976.9 GBG66662.1 - 0.011 15.4 0.3 0.031 14.0 0.2 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 GBG66662.1 - 0.017 15.3 0.3 1.1 9.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG66662.1 - 0.025 15.2 0.0 0.1 13.3 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat PDZ PF00595.24 GBG66662.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 PDZ domain ANAPC3 PF12895.7 GBG66662.1 - 0.064 13.5 0.6 0.13 12.5 0.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 U1snRNP70_N PF12220.8 GBG66662.1 - 0.27 11.9 3.1 0.51 11.0 3.1 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Retrotrans_gag PF03732.17 GBG66663.1 - 0.0028 17.9 0.8 0.022 15.1 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein DDHD PF02862.17 GBG66663.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.7 2 1 0 2 2 2 0 DDHD domain FYDLN_acid PF09538.10 GBG66663.1 - 2.4 8.9 13.7 0.64 10.7 3.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RNA_pol_Rpc4 PF05132.14 GBG66663.1 - 2.8 8.3 10.9 0.076 13.4 2.3 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Sec62 PF03839.16 GBG66663.1 - 3.3 7.2 7.9 0.18 11.3 0.1 2.3 2 1 0 2 2 2 0 Translocation protein Sec62 SpoIIP PF07454.11 GBG66663.1 - 4.8 6.5 13.3 0.091 12.2 3.7 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4366 PF14283.6 GBG66663.1 - 10 6.2 9.3 0.43 10.6 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) OB_NTP_bind PF07717.16 GBG66664.1 - 5.5e-19 68.3 0.0 6.1e-18 65.0 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GBG66664.1 - 9.5e-19 67.7 0.1 9.5e-19 67.7 0.1 3.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GBG66664.1 - 1e-10 41.9 0.0 5.3e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GBG66664.1 - 1.7e-06 27.9 0.1 4.6e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GBG66664.1 - 2.4e-06 27.9 0.0 8.3e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GBG66664.1 - 0.0039 16.6 0.0 0.0098 15.3 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.6 GBG66664.1 - 0.011 16.0 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GBG66664.1 - 0.032 13.3 0.0 0.068 12.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein OEP PF02321.18 GBG66664.1 - 0.22 11.3 2.2 0.82 9.5 2.2 2.0 1 0 0 1 1 1 0 Outer membrane efflux protein S1 PF00575.23 GBG66665.1 - 1.6e-23 82.8 1.9 2.5e-16 59.7 0.1 2.6 2 0 0 2 2 2 2 S1 RNA binding domain DUF2103 PF09876.9 GBG66665.1 - 3.7e-06 26.8 0.1 1.4e-05 25.0 0.1 2.0 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2103) PCB_OB PF17092.5 GBG66665.1 - 0.0016 19.2 1.2 0.11 13.3 0.1 2.9 1 1 1 2 2 2 1 Penicillin-binding protein OB-like domain LytB_WW PF18342.1 GBG66665.1 - 0.11 12.6 0.0 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 Endo-beta-N-acetylglucosaminidase LytB WW domain FAD_binding_1 PF00667.20 GBG66666.1 - 1.4e-49 168.7 0.0 2e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GBG66666.1 - 1.1e-25 90.5 0.0 2.9e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 GBG66666.1 - 7.8e-17 61.9 0.0 1.8e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 GBG66666.1 - 0.009 16.3 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain LPG_synthase_TM PF03706.13 GBG66666.1 - 0.012 15.1 0.4 0.019 14.5 0.4 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region DUF4131 PF13567.6 GBG66666.1 - 0.28 10.8 0.8 0.53 9.9 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Sigma70_ner PF04546.13 GBG66667.1 - 6.8 6.5 12.5 3 7.7 2.7 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Glyco_hydro_115 PF15979.5 GBG66668.1 - 0.084 12.3 0.0 7 6.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 115 Pkinase PF00069.25 GBG66670.1 - 6e-72 242.2 0.0 9.3e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG66670.1 - 2.5e-51 174.5 0.0 4.2e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 GBG66670.1 - 8.2e-08 32.0 2.4 2.4 8.3 0.1 6.4 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Pkinase_fungal PF17667.1 GBG66670.1 - 9.7e-06 24.6 0.2 3.1e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase V-ATPase_H_C PF11698.8 GBG66670.1 - 0.0014 18.8 0.8 0.0037 17.4 0.8 1.7 1 0 0 1 1 1 1 V-ATPase subunit H FTA2 PF13095.6 GBG66670.1 - 0.05 13.2 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GBG66670.1 - 0.19 11.0 0.0 0.38 10.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Ribosomal_60s PF00428.19 GBG66670.1 - 0.9 10.2 16.8 3.4 8.3 16.8 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pyrid_oxidase_2 PF13883.6 GBG66671.1 - 5.6e-17 62.2 0.3 1.9e-16 60.5 0.0 2.0 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 GBG66671.1 - 1.5e-07 31.5 0.1 4.7e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Mito_carr PF00153.27 GBG66672.1 - 1e-40 137.6 0.5 6.5e-15 54.8 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein UCH PF00443.29 GBG66673.1 - 3e-42 144.9 0.0 6.6e-42 143.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG66673.1 - 3.1e-08 33.6 0.0 9.8e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase LSM PF01423.22 GBG66675.1 - 1.8e-06 27.6 0.1 0.00011 21.8 0.1 2.3 2 0 0 2 2 2 2 LSM domain SM-ATX PF14438.6 GBG66675.1 - 0.065 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain ARID PF01388.21 GBG66676.1 - 5.2e-13 49.5 0.0 8.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain CHAT PF12770.7 GBG66676.1 - 0.015 14.7 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 CHAT domain DUF2483 PF10656.9 GBG66677.1 - 0.014 15.5 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) DUF4407 PF14362.6 GBG66677.1 - 0.68 9.2 33.8 0.66 9.3 9.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) RT_RNaseH PF17917.1 GBG66678.1 - 6.9e-21 74.5 0.0 1.4e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66678.1 - 6.7e-19 67.8 0.0 1.4e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG66678.1 - 0.00013 22.5 0.0 0.00029 21.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66678.1 - 0.0066 17.1 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG66678.1 - 0.27 11.5 1.3 1.1 9.5 1.3 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein CCT PF06203.14 GBG66679.1 - 9.5e-18 64.0 13.8 1.4e-17 63.4 13.8 1.3 1 0 0 1 1 1 1 CCT motif Thioredoxin PF00085.20 GBG66680.1 - 6.7e-07 29.2 0.0 0.011 15.7 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 GBG66680.1 - 0.042 14.0 0.0 0.85 9.8 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin-like DUF2828 PF11443.8 GBG66680.1 - 1.2 7.1 5.1 2.3 6.2 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DDHD PF02862.17 GBG66680.1 - 3.8 7.6 7.4 0.2 11.8 0.3 2.3 3 0 0 3 3 3 0 DDHD domain adh_short_C2 PF13561.6 GBG66681.1 - 2.1e-52 178.0 3.5 1.6e-34 119.5 3.3 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GBG66681.1 - 4.5e-49 166.6 5.7 5.7e-47 159.7 5.5 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 GBG66681.1 - 4.7e-21 75.5 2.0 7.1e-21 74.9 2.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GBG66681.1 - 0.027 13.9 0.3 0.045 13.2 0.2 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GYF_2 PF14237.6 GBG66681.1 - 0.17 11.7 0.1 0.56 10.1 0.1 1.9 1 0 0 1 1 1 0 GYF domain 2 Peptidase_M24 PF00557.24 GBG66682.1 - 6.9e-26 91.2 0.0 1.1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 GBG66682.1 - 1.5e-20 73.9 0.1 3.3e-17 63.0 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 GBG66682.1 - 2e-13 50.2 0.2 3.7e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Hamartin PF04388.12 GBG66682.1 - 6.6 5.3 6.8 9.8 4.7 6.8 1.1 1 0 0 1 1 1 0 Hamartin protein N6_N4_Mtase PF01555.18 GBG66683.1 - 3.6e-08 33.4 0.0 5.9e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 DNA methylase Histone PF00125.24 GBG66684.1 - 6.9e-06 26.5 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 N6_N4_Mtase PF01555.18 GBG66685.1 - 2e-07 31.0 0.0 2.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 DNA methylase MbeB_N PF04837.12 GBG66685.1 - 0.21 11.9 0.1 0.46 10.8 0.1 1.5 1 0 0 1 1 1 0 MbeB-like, N-term conserved region DUF4360 PF14273.6 GBG66686.1 - 3e-44 151.0 0.6 3.5e-44 150.8 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF5029 PF16432.5 GBG66687.1 - 0.083 12.4 0.3 0.17 11.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) DUF4554 PF15091.6 GBG66687.1 - 7.8 5.3 7.6 0.37 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) DUF4360 PF14273.6 GBG66688.1 - 5.1e-41 140.5 0.7 5.8e-41 140.3 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66690.1 - 1.1e-40 139.4 0.4 2e-40 138.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DNA_pol_phi PF04931.13 GBG66690.1 - 1.6 6.8 6.4 2.7 6.0 6.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF4360 PF14273.6 GBG66691.1 - 3.7e-44 150.7 0.4 4.2e-44 150.5 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66692.1 - 1.4e-41 142.4 0.7 1.6e-41 142.2 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MRP-S35 PF10246.9 GBG66693.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 DUF4360 PF14273.6 GBG66694.1 - 7.9e-38 130.1 1.3 1.3e-37 129.4 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH PF17917.1 GBG66695.1 - 1.5e-22 79.8 0.0 3.7e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66695.1 - 9.4e-22 76.9 0.0 3e-21 75.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66695.1 - 4.7e-13 49.2 0.0 2.8e-11 43.4 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG66695.1 - 0.094 12.8 1.9 0.18 11.9 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG66697.1 - 3.3e-51 171.4 0.1 2.4e-26 91.7 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66697.1 - 4.9e-47 158.6 1.2 4.8e-26 91.1 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66697.1 - 4.1e-09 36.3 0.0 0.00068 19.2 0.0 2.8 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) SPACA9 PF15120.6 GBG66697.1 - 0.43 10.3 5.3 0.21 11.3 0.3 2.8 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 DUF4360 PF14273.6 GBG66698.1 - 1.2e-40 139.3 1.4 1.4e-40 139.1 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH PF17917.1 GBG66701.1 - 1.1e-21 77.1 0.0 2.5e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66701.1 - 7e-20 70.9 0.0 2.5e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66701.1 - 2.7e-10 40.2 0.4 6.6e-10 38.9 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG66701.1 - 3.2e-07 30.8 0.7 1.2e-06 29.0 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66701.1 - 3.4e-05 24.4 0.7 0.00013 22.5 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG66701.1 - 0.0011 18.8 0.4 0.0019 18.0 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG66701.1 - 0.005 17.1 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein RVP PF00077.20 GBG66701.1 - 0.017 15.4 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4360 PF14273.6 GBG66704.1 - 4.7e-42 143.9 0.0 5.4e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) ATP-synt_J PF04911.12 GBG66704.1 - 0.083 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 ATP synthase j chain DUF4360 PF14273.6 GBG66705.1 - 6.3e-41 140.2 0.1 7.4e-41 140.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66706.1 - 8.9e-47 159.2 0.3 1e-46 159.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66708.1 - 3e-41 141.2 1.3 3.4e-41 141.0 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Topo_Zn_Ribbon PF08272.11 GBG66709.1 - 0.069 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like MAP17 PF15807.5 GBG66710.1 - 0.0068 16.6 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RVT_1 PF00078.27 GBG66711.1 - 0.0002 20.9 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG66711.1 - 0.0042 17.7 0.1 0.014 16.0 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66711.1 - 0.0096 16.5 0.4 0.034 14.7 0.1 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease gag-asp_proteas PF13975.6 GBG66712.1 - 8.4e-06 26.3 0.1 3.8e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG66712.1 - 0.00044 20.2 0.5 0.0012 18.8 0.5 1.8 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG66712.1 - 0.00064 20.3 0.0 0.0017 19.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG66712.1 - 0.015 15.1 0.5 0.029 14.1 0.5 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG66712.1 - 0.1 12.9 0.0 3 8.2 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein rve PF00665.26 GBG66713.1 - 4.5e-07 30.1 0.3 3.4e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain DUF659 PF04937.15 GBG66715.1 - 3.9e-14 52.8 0.0 6e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG66715.1 - 0.012 15.3 0.2 0.038 13.8 0.0 1.8 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region DUF4360 PF14273.6 GBG66716.1 - 9.6e-44 149.4 0.5 1.2e-43 149.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66720.1 - 9.5e-46 155.9 0.4 1.3e-45 155.5 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Gam PF06064.11 GBG66720.1 - 0.11 12.7 0.0 0.65 10.3 0.0 2.0 2 0 0 2 2 2 0 Host-nuclease inhibitor protein Gam DUF4360 PF14273.6 GBG66721.1 - 3.8e-41 140.9 0.6 4.4e-41 140.7 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66722.1 - 6.3e-47 159.7 0.1 7.4e-47 159.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Cadherin_5 PF17892.1 GBG66722.1 - 0.12 12.4 0.2 1.4 8.9 0.1 2.4 1 1 2 3 3 3 0 Cadherin-like domain DUF4360 PF14273.6 GBG66723.1 - 2.6e-48 164.2 0.3 3e-48 164.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66724.1 - 3.8e-38 131.1 0.1 7.7e-38 130.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) ATP-synt_J PF04911.12 GBG66724.1 - 0.16 11.5 0.1 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 ATP synthase j chain MDM10 PF12519.8 GBG66725.1 - 0.13 11.1 1.5 0.15 10.9 1.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF2514 PF10721.9 GBG66725.1 - 0.5 10.4 13.4 0.1 12.6 9.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DUF1053 PF06327.14 GBG66725.1 - 1.4 9.5 7.7 0.51 10.9 4.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) DUF572 PF04502.13 GBG66725.1 - 1.7 8.2 13.3 2.4 7.7 13.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1682 PF07946.14 GBG66725.1 - 2.2 7.4 14.3 3.8 6.6 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 GBG66725.1 - 6.4 5.4 4.5 7.8 5.1 4.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4360 PF14273.6 GBG66726.1 - 1e-47 162.3 0.2 1.2e-47 162.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Big_7 PF17957.1 GBG66726.1 - 0.027 15.2 0.1 0.21 12.4 0.0 2.4 3 0 0 3 3 3 0 Bacterial Ig domain DUF4360 PF14273.6 GBG66727.1 - 2.2e-47 161.2 0.2 2.5e-47 161.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pilin_N PF07790.11 GBG66727.1 - 0.072 14.0 0.0 6.8 7.7 0.2 2.5 3 0 0 3 3 3 0 Archaeal Type IV pilin, N-terminal DUF4360 PF14273.6 GBG66728.1 - 8.5e-47 159.3 0.4 1e-46 159.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RVT_1 PF00078.27 GBG66729.1 - 3.9e-25 88.7 0.1 6.1e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG66729.1 - 3.4e-07 30.1 0.0 8.3e-07 28.8 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG66729.1 - 3.7e-05 24.3 0.0 8.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG66729.1 - 0.0013 18.9 0.0 0.0048 17.1 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG66729.1 - 0.0031 18.0 0.0 0.006 17.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG66729.1 - 0.0034 17.2 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF5401 PF17380.2 GBG66730.1 - 0.12 10.4 18.2 0.14 10.2 18.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) FAM60A PF15396.6 GBG66730.1 - 0.54 10.2 6.0 0.57 10.2 6.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A LicD PF04991.13 GBG66730.1 - 0.64 10.1 4.0 0.78 9.8 4.0 1.0 1 0 0 1 1 1 0 LicD family PA26 PF04636.13 GBG66730.1 - 0.73 8.7 8.1 0.82 8.5 8.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TP53IP5 PF15331.6 GBG66730.1 - 1.5 8.9 10.2 1.7 8.7 10.2 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Vfa1 PF08432.10 GBG66730.1 - 2 8.7 14.8 2.5 8.4 14.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPL5 PF18168.1 GBG66730.1 - 2.9 7.1 6.8 3.1 7.0 6.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Med9 PF07544.13 GBG66730.1 - 3.5 7.8 10.4 11 6.2 4.3 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DDHD PF02862.17 GBG66730.1 - 3.8 7.6 5.7 4.2 7.5 5.7 1.1 1 0 0 1 1 1 0 DDHD domain Ureide_permease PF07168.11 GBG66730.1 - 7.9 5.1 5.7 9 4.9 5.7 1.1 1 0 0 1 1 1 0 Ureide permease DUF4360 PF14273.6 GBG66734.1 - 6.5e-37 127.1 1.0 1.4e-36 126.0 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Myb_DNA-bind_4 PF13837.6 GBG66734.1 - 0.0063 16.9 0.5 0.48 10.8 0.2 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF4360 PF14273.6 GBG66736.1 - 4.1e-47 160.4 0.2 4.7e-47 160.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66737.1 - 5e-35 121.0 0.1 7.9e-35 120.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DDE_Tnp_4 PF13359.6 GBG66737.1 - 9.5e-23 80.6 0.0 2.9e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66737.1 - 6.8e-12 45.4 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66737.1 - 0.017 14.8 0.0 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG66738.1 - 3.4e-06 27.3 2.7 3.4e-06 27.3 2.7 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG66738.1 - 0.00078 19.5 0.9 0.0021 18.1 0.9 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG66738.1 - 0.0055 16.9 0.3 0.011 16.0 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG66738.1 - 0.038 14.2 1.2 0.12 12.6 1.2 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain Drc1-Sld2 PF11719.8 GBG66738.1 - 0.086 12.4 1.2 0.14 11.6 1.2 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein MADF_DNA_bdg PF10545.9 GBG66738.1 - 0.84 10.0 6.1 0.07 13.4 1.0 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4360 PF14273.6 GBG66739.1 - 6.6e-46 156.4 0.2 7.5e-46 156.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66740.1 - 6.5e-46 156.4 0.2 7.5e-46 156.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66741.1 - 9.3e-44 149.4 1.0 1.4e-43 148.8 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4360) DDE_Tnp_4 PF13359.6 GBG66741.1 - 0.001 18.7 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Urb2 PF10441.9 GBG66741.1 - 0.0034 17.3 0.0 2 8.3 0.0 2.4 2 1 0 2 2 2 2 Urb2/Npa2 family Nop53 PF07767.11 GBG66742.1 - 0.0011 18.4 32.7 0.0011 18.4 32.7 3.9 3 1 0 3 3 3 1 Nop53 (60S ribosomal biogenesis) DUF4360 PF14273.6 GBG66743.1 - 6.8e-48 162.9 0.3 7.7e-48 162.7 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66744.1 - 1.5e-46 158.5 0.1 1.8e-46 158.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Cadherin_5 PF17892.1 GBG66744.1 - 0.19 11.7 0.3 2.1 8.4 0.1 2.4 1 1 2 3 3 3 0 Cadherin-like domain DUF4360 PF14273.6 GBG66745.1 - 2.9e-43 147.8 0.4 3.9e-43 147.4 0.2 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4360) Myb_DNA-bind_4 PF13837.6 GBG66746.1 - 0.041 14.3 0.1 0.079 13.3 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain XPB_DRD PF18458.1 GBG66746.1 - 0.065 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain Peptidase_C48 PF02902.19 GBG66749.1 - 1.4e-08 34.9 0.0 3.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF963 PF06131.11 GBG66749.1 - 0.82 9.1 27.3 0.48 9.9 1.0 4.7 4 1 0 4 4 4 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) RibD_C PF01872.17 GBG66750.1 - 4.4 7.1 17.0 21 4.9 6.2 2.4 1 1 1 2 2 2 0 RibD C-terminal domain DUF4235 PF14019.6 GBG66751.1 - 0.025 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) ASD2 PF08687.11 GBG66752.1 - 0.11 12.1 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 UBA2_C PF16195.5 GBG66752.1 - 0.11 13.2 1.5 0.23 12.2 1.5 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DUF4360 PF14273.6 GBG66753.1 - 5.4e-25 88.3 0.0 5.9e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66754.1 - 4.7e-33 114.5 0.1 5.3e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66755.1 - 2e-40 138.6 1.0 2.2e-40 138.4 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Claudin_2 PF13903.6 GBG66756.1 - 0.11 12.2 1.6 0.19 11.4 1.6 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction RT_RNaseH PF17917.1 GBG66757.1 - 3e-19 69.2 0.0 6.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66757.1 - 2.8e-17 62.6 0.0 8e-17 61.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66757.1 - 0.0024 18.1 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG66757.1 - 0.23 11.6 0.7 0.49 10.6 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG66758.1 - 5.5e-13 49.0 0.0 1.5e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG66758.1 - 3.7e-06 27.2 1.1 9.7e-06 25.9 0.5 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 GBG66759.1 - 0.00015 21.9 0.2 0.00015 21.9 0.2 2.3 3 0 0 3 3 3 1 Retrotransposon gag protein Macoilin PF09726.9 GBG66759.1 - 0.031 12.9 1.3 0.047 12.2 1.3 1.2 1 0 0 1 1 1 0 Macoilin family Mt_ATP-synt_B PF05405.14 GBG66759.1 - 0.41 10.2 3.7 0.81 9.3 3.7 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ZapB PF06005.12 GBG66759.1 - 2.3 8.7 9.1 2.8 8.5 7.5 1.9 2 0 0 2 2 2 0 Cell division protein ZapB RVT_1 PF00078.27 GBG66760.1 - 3.1e-28 98.8 0.1 4.8e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66760.1 - 5.2e-25 87.4 0.0 1.2e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66760.1 - 8.3e-21 74.2 0.0 1.5e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG66761.1 - 1.8e-06 27.8 3.0 1.8e-06 27.8 3.0 1.9 2 0 0 2 2 2 1 Zinc knuckle IMD PF08397.11 GBG66761.1 - 0.086 12.2 6.0 0.13 11.6 6.0 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain zf-CCHC_2 PF13696.6 GBG66761.1 - 3.2 7.7 6.8 0.18 11.7 1.7 1.6 2 0 0 2 2 2 0 Zinc knuckle DUF4360 PF14273.6 GBG66762.1 - 7.8e-41 139.9 1.0 8.9e-41 139.7 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CathepsinC_exc PF08773.11 GBG66762.1 - 0.09 13.1 0.3 0.83 9.9 0.1 2.1 2 0 0 2 2 2 0 Cathepsin C exclusion domain DUF4360 PF14273.6 GBG66763.1 - 2.2e-30 105.8 0.1 2.4e-30 105.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CathepsinC_exc PF08773.11 GBG66763.1 - 0.053 13.8 0.1 0.93 9.8 0.0 2.0 2 0 0 2 2 2 0 Cathepsin C exclusion domain DUF4360 PF14273.6 GBG66764.1 - 6.7e-43 146.6 0.2 7.7e-43 146.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Gam PF06064.11 GBG66764.1 - 0.18 12.1 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam DUF4360 PF14273.6 GBG66766.1 - 1.9e-45 154.9 0.2 2.3e-45 154.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66767.1 - 1.5e-23 83.6 0.5 2.5e-23 82.9 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) ABC_tran_CTD PF16326.5 GBG66767.1 - 0.027 14.7 12.8 0.036 14.3 1.4 3.5 3 1 1 4 4 4 0 ABC transporter C-terminal domain TSC22 PF01166.18 GBG66767.1 - 0.094 13.0 6.5 0.4 11.0 0.2 3.6 2 1 0 3 3 3 0 TSC-22/dip/bun family Osmo_CC PF08946.10 GBG66767.1 - 0.49 10.7 3.9 1.5 9.1 0.9 3.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Presenilin PF01080.17 GBG66768.1 - 0.56 8.9 23.5 0.66 8.7 23.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4360 PF14273.6 GBG66769.1 - 3.1e-41 141.2 1.4 3.5e-41 141.0 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CathepsinC_exc PF08773.11 GBG66769.1 - 0.089 13.1 0.4 0.76 10.1 0.1 2.1 2 0 0 2 2 2 0 Cathepsin C exclusion domain DUF4360 PF14273.6 GBG66770.1 - 1.5e-45 155.2 0.2 1.8e-45 155.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG66771.1 - 3.2e-26 91.3 0.0 5.2e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66771.1 - 5.3e-25 87.7 0.0 1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66771.1 - 3.2e-10 39.9 0.0 4.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG66772.1 - 0.00071 20.1 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66772.1 - 0.011 16.4 0.0 0.022 15.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG66772.1 - 0.094 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4360 PF14273.6 GBG66773.1 - 1.5e-44 152.0 0.2 2.3e-44 151.4 0.2 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66775.1 - 1.1e-40 139.4 0.3 1.6e-40 138.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PAXIP1_C PF15364.6 GBG66776.1 - 0.011 16.1 1.8 0.018 15.3 1.8 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein D123 PF07065.14 GBG66776.1 - 0.1 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 D123 F-box_4 PF15966.5 GBG66776.1 - 0.19 11.6 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 F-box Pes-10 PF07149.11 GBG66776.1 - 0.5 9.4 5.8 0.75 8.8 5.8 1.3 1 0 0 1 1 1 0 Pes-10 RT_RNaseH_2 PF17919.1 GBG66777.1 - 1.4e-23 82.8 0.0 2.4e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66777.1 - 2e-20 73.1 0.0 4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66777.1 - 2.3e-15 56.7 0.1 3.3e-15 56.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG66777.1 - 3.2 7.0 17.2 4.4 6.5 17.2 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG66777.1 - 3.2 5.9 10.8 4.6 5.4 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG66777.1 - 9.6 4.3 14.5 12 3.9 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4360 PF14273.6 GBG66778.1 - 4.3e-40 137.5 1.1 6.1e-40 137.0 1.0 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66779.1 - 1.8e-42 145.2 0.3 2.8e-42 144.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66780.1 - 3.4e-38 131.3 2.6 3.9e-38 131.1 2.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DDRGK PF09756.9 GBG66781.1 - 3.4 7.2 23.5 5.9 6.4 23.5 1.4 1 0 0 1 1 1 0 DDRGK domain Dimer_Tnp_hAT PF05699.14 GBG66782.1 - 0.056 13.2 0.3 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Roughex PF06020.11 GBG66782.1 - 0.14 11.2 7.9 0.25 10.4 7.9 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 GBG66782.1 - 1.2 8.7 26.5 2.2 7.8 26.5 1.4 1 0 0 1 1 1 0 Spt20 family DUF4746 PF15928.5 GBG66782.1 - 2.2 7.6 10.9 4.3 6.7 8.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 GBG66782.1 - 3.3 6.4 11.2 4.7 5.9 11.2 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 GBG66782.1 - 7.2 3.6 8.8 9.5 3.2 8.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 GBG66782.1 - 7.6 6.5 5.5 12 5.8 5.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SKA1 PF07160.12 GBG66782.1 - 9.4 6.0 12.5 20 4.9 12.5 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4360 PF14273.6 GBG66783.1 - 8.9e-46 156.0 0.2 1e-45 155.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Diphthami_syn_2 PF01902.17 GBG66784.1 - 0.14 11.7 0.7 1.2 8.6 0.0 2.3 2 1 0 2 2 2 0 Diphthamide synthase DUF2670 PF10875.8 GBG66784.1 - 0.18 11.9 0.5 0.61 10.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2670) ABC_tran_CTD PF16326.5 GBG66784.1 - 0.32 11.3 6.6 0.15 12.3 1.0 3.0 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF2120 PF09893.9 GBG66784.1 - 0.56 10.3 3.5 7.8 6.6 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) TSC22 PF01166.18 GBG66784.1 - 1.9 8.8 5.0 1.3 9.4 0.3 3.0 2 1 2 4 4 4 0 TSC-22/dip/bun family TMF_TATA_bd PF12325.8 GBG66784.1 - 3.5 7.9 11.7 0.53 10.5 0.2 3.0 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4360 PF14273.6 GBG66787.1 - 2.3e-38 131.8 5.7 2.6e-38 131.6 5.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SUR7 PF06687.12 GBG66787.1 - 0.0097 15.6 0.1 0.012 15.2 0.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family zf-CCHC PF00098.23 GBG66788.1 - 7.9e-07 28.9 0.5 1.9e-06 27.7 0.5 1.7 1 0 0 1 1 1 1 Zinc knuckle Folliculin PF11704.8 GBG66788.1 - 4.1 7.3 7.0 4.6 7.1 2.2 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4360 PF14273.6 GBG66789.1 - 2.3e-38 131.8 5.7 2.6e-38 131.6 5.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SUR7 PF06687.12 GBG66789.1 - 0.0097 15.6 0.1 0.012 15.2 0.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4360 PF14273.6 GBG66790.1 - 6.7e-45 153.1 0.3 7.8e-45 152.9 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66791.1 - 1.1e-45 155.7 0.1 1.3e-45 155.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66792.1 - 2.4e-50 170.9 0.1 3e-50 170.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG66794.1 - 7.9e-36 123.6 0.0 8.5e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) FokI_N PF02981.15 GBG66795.1 - 0.12 12.5 0.3 0.15 12.2 0.3 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain PA26 PF04636.13 GBG66795.1 - 0.86 8.5 10.1 1.1 8.2 10.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TP53IP5 PF15331.6 GBG66795.1 - 2.7 8.1 10.8 2.8 8.0 10.8 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF913 PF06025.12 GBG66795.1 - 3.9 6.4 6.1 4.2 6.2 6.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 GBG66795.1 - 4.7 7.3 7.2 5.1 7.2 7.2 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_C48 PF02902.19 GBG66796.1 - 1.7e-09 37.8 0.0 4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RVT_1 PF00078.27 GBG66798.1 - 5.1e-30 104.6 0.1 1.6e-29 103.0 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66798.1 - 1.4e-28 99.2 0.0 3.4e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66798.1 - 1.8e-28 98.5 0.0 7.7e-15 54.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66798.1 - 1.3e-14 54.0 0.9 4.1e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG66798.1 - 2.8e-12 46.9 0.0 1.4e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG66798.1 - 2.1e-05 24.7 0.0 5.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF4360 PF14273.6 GBG66799.1 - 8.7e-29 100.6 0.8 1e-28 100.4 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NPCBM_assoc PF10633.9 GBG66799.1 - 0.012 15.8 0.3 0.076 13.3 0.1 2.3 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Big_3_2 PF12245.8 GBG66799.1 - 0.35 11.1 1.8 1.7 8.9 0.1 2.1 1 1 1 2 2 2 0 Bacterial Ig-like domain DUF4402 PF14352.6 GBG66799.1 - 0.62 10.7 6.3 15 6.2 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4402) RVT_1 PF00078.27 GBG66800.1 - 1e-18 67.7 0.2 2e-18 66.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Seryl_tRNA_N PF02403.22 GBG66800.1 - 0.029 14.6 3.3 0.069 13.4 3.3 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4360 PF14273.6 GBG66801.1 - 9.6e-26 90.7 0.6 1.1e-25 90.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NPCBM_assoc PF10633.9 GBG66801.1 - 0.032 14.5 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Myb_DNA-bind_4 PF13837.6 GBG66802.1 - 2.2e-08 34.4 2.6 2.2e-08 34.4 2.6 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG66802.1 - 9.6e-05 22.6 2.1 0.00077 19.7 0.6 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG66802.1 - 0.0012 18.9 0.2 0.0045 17.1 0.5 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG66802.1 - 0.0024 17.9 0.9 0.0049 16.9 0.9 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG66803.1 - 2.4e-25 89.1 0.0 3.3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66803.1 - 9.6e-15 54.7 0.0 1.4e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66803.1 - 0.0006 19.5 0.3 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG66803.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain RVT_1 PF00078.27 GBG66804.1 - 1.6e-15 57.2 0.0 3.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cohesin_HEAT PF12765.7 GBG66804.1 - 0.021 15.1 0.2 2.8 8.3 0.1 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion GBP_repeat PF02526.14 GBG66804.1 - 0.13 12.0 0.7 7.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Glycophorin-binding protein N6_N4_Mtase PF01555.18 GBG66805.1 - 0.0022 17.7 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 DNA methylase Nop14 PF04147.12 GBG66806.1 - 0.5 8.5 22.3 0.55 8.4 22.3 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG66806.1 - 0.62 9.4 16.7 0.67 9.2 16.7 1.0 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 GBG66806.1 - 0.69 9.5 18.8 1.1 8.8 18.8 1.4 1 0 0 1 1 1 0 PPP4R2 DUF913 PF06025.12 GBG66806.1 - 0.7 8.8 4.7 0.7 8.8 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CobT PF06213.12 GBG66806.1 - 0.73 9.2 17.7 0.88 8.9 17.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2076 PF09849.9 GBG66806.1 - 3.1 7.8 9.3 3.4 7.6 9.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3295 PF11702.8 GBG66806.1 - 3.2 7.0 13.0 3.4 6.9 13.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Presenilin PF01080.17 GBG66806.1 - 3.2 6.4 5.4 3.6 6.2 5.4 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG66806.1 - 5.5 5.7 9.5 6.1 5.5 9.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NOA36 PF06524.12 GBG66806.1 - 5.5 6.2 22.8 7.5 5.8 22.8 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG66806.1 - 7.6 4.5 28.6 7.9 4.4 28.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG66806.1 - 8.2 5.7 23.5 9.6 5.5 23.5 1.1 1 0 0 1 1 1 0 SDA1 SGT1 PF07093.11 GBG66806.1 - 8.9 4.6 12.3 9.4 4.5 12.3 1.1 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.14 GBG66806.1 - 9.5 4.4 18.4 11 4.2 18.4 1.1 1 0 0 1 1 1 0 CDC45-like protein UEV PF05743.13 GBG66807.1 - 1.3e-17 63.8 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain zf-CCHC PF00098.23 GBG66808.1 - 0.21 11.7 1.7 0.41 10.8 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG66809.1 - 1.5e-13 50.6 0.1 3.3e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66809.1 - 3.5e-13 49.8 0.0 7.7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG66809.1 - 4.3e-07 30.4 0.0 1e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66809.1 - 0.00037 21.1 0.0 0.00089 19.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG66809.1 - 0.00059 19.6 0.8 0.0012 18.7 0.8 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG66809.1 - 0.0022 18.3 0.0 0.0057 16.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG66809.1 - 0.018 15.3 0.6 0.035 14.3 0.6 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Peptidase_A2B PF12384.8 GBG66809.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase Jnk-SapK_ap_N PF09744.9 GBG66809.1 - 0.63 10.3 8.5 0.022 15.0 1.5 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 GBG66809.1 - 8.6 6.4 9.8 1.6 8.8 5.8 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Sec63 PF02889.16 GBG66811.1 - 3.7e-163 540.8 0.0 1.4e-92 309.5 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GBG66811.1 - 9.5e-53 178.6 1.8 1.8e-26 93.0 0.7 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 GBG66811.1 - 1.5e-34 118.5 3.5 1.5e-34 118.5 3.5 2.5 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 GBG66811.1 - 8.2e-26 91.0 0.0 7.5e-13 48.8 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GBG66811.1 - 1.1e-12 48.3 0.0 1.3e-06 28.7 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 GBG66811.1 - 6.2e-07 29.8 5.6 0.012 15.8 0.0 4.3 4 1 0 4 4 4 2 AAA domain AAA_25 PF13481.6 GBG66811.1 - 5.3e-05 22.9 0.2 0.33 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 GBG66811.1 - 0.00023 20.3 0.0 0.037 13.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 GBG66811.1 - 0.0011 19.3 3.0 0.97 9.8 0.4 3.6 3 1 0 3 3 3 2 AAA domain PhoH PF02562.16 GBG66811.1 - 0.025 14.0 0.1 1.7 8.1 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 GBG66811.1 - 0.042 13.4 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 GBG66811.1 - 0.12 12.1 0.2 12 5.6 0.0 3.7 4 1 0 4 4 4 0 IstB-like ATP binding protein AAA_11 PF13086.6 GBG66811.1 - 0.73 9.6 11.3 0.22 11.3 0.1 4.0 5 1 0 5 5 5 0 AAA domain Sec63 PF02889.16 GBG66812.1 - 3.7e-163 540.8 0.0 1.4e-92 309.5 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GBG66812.1 - 9.5e-53 178.6 1.8 1.8e-26 93.0 0.7 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 GBG66812.1 - 1.5e-34 118.5 3.5 1.5e-34 118.5 3.5 2.5 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 GBG66812.1 - 8.2e-26 91.0 0.0 7.5e-13 48.8 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GBG66812.1 - 1.1e-12 48.3 0.0 1.3e-06 28.7 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 GBG66812.1 - 6.2e-07 29.8 5.6 0.012 15.8 0.0 4.3 4 1 0 4 4 4 2 AAA domain AAA_25 PF13481.6 GBG66812.1 - 5.3e-05 22.9 0.2 0.33 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 GBG66812.1 - 0.00023 20.3 0.0 0.037 13.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 GBG66812.1 - 0.0011 19.3 3.0 0.97 9.8 0.4 3.6 3 1 0 3 3 3 2 AAA domain PhoH PF02562.16 GBG66812.1 - 0.025 14.0 0.1 1.7 8.1 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 GBG66812.1 - 0.042 13.4 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 GBG66812.1 - 0.12 12.1 0.2 12 5.6 0.0 3.7 4 1 0 4 4 4 0 IstB-like ATP binding protein AAA_11 PF13086.6 GBG66812.1 - 1.1 9.0 11.9 0.22 11.3 0.1 4.0 5 1 0 5 5 5 0 AAA domain Glyco_hydro_31 PF01055.26 GBG66813.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 PFL-like PF02901.15 GBG66814.1 - 1.9e-197 657.9 0.0 2.6e-197 657.4 0.0 1.1 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 GBG66814.1 - 3.5e-23 82.2 0.1 2.5e-17 63.4 0.1 2.7 2 0 0 2 2 2 2 Glycine radical MtrB PF05440.12 GBG66814.1 - 0.0082 16.5 0.0 0.031 14.7 0.0 2.0 2 0 0 2 2 2 1 Tetrahydromethanopterin S-methyltransferase subunit B Retrotrans_gag PF03732.17 GBG66815.1 - 0.0047 17.2 0.3 0.046 14.0 0.1 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG66815.1 - 0.024 14.2 0.0 0.057 12.9 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) A_thal_3526 PF09713.10 GBG66816.1 - 2.1e-26 91.9 0.3 3.3e-26 91.3 0.3 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) DUF3177 PF11375.8 GBG66816.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) RT_RNaseH_2 PF17919.1 GBG66817.1 - 4.2e-20 71.6 0.0 8.4e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66817.1 - 1.5e-17 63.8 0.0 7e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG66817.1 - 1e-09 38.6 0.0 2.2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG66817.1 - 8.7e-06 26.3 0.0 2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66817.1 - 6.5e-05 23.4 0.0 0.00019 21.9 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG66817.1 - 0.0082 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG66817.1 - 0.012 15.9 0.2 0.7 10.2 0.0 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein RVP_2 PF08284.11 GBG66817.1 - 0.037 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease AP1AR PF15745.5 GBG66817.1 - 2.4 7.7 6.0 4.4 6.9 6.0 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein NPV_P10 PF05531.12 GBG66818.1 - 3.8 8.0 45.8 4.1 7.9 4.8 9.0 8 1 0 8 8 8 0 Nucleopolyhedrovirus P10 protein DUF4041 PF13250.6 GBG66818.1 - 6.1 6.8 11.5 2.3 8.2 0.2 5.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) Sua5_yciO_yrdC PF01300.18 GBG66820.1 - 0.0043 16.6 1.8 0.0072 15.8 1.8 1.3 1 0 0 1 1 1 1 Telomere recombination DUF4837 PF16125.5 GBG66820.1 - 0.15 11.0 4.1 0.17 10.9 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4837) NA37 PF04245.13 GBG66820.1 - 0.46 9.9 8.7 0.67 9.4 8.7 1.2 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein FAM60A PF15396.6 GBG66820.1 - 0.62 10.0 3.8 0.63 10.0 3.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A IncFII_repA PF02387.15 GBG66820.1 - 0.86 8.8 6.4 1.2 8.3 6.4 1.2 1 0 0 1 1 1 0 IncFII RepA protein family EMC3_TMCO1 PF01956.16 GBG66820.1 - 1.5 8.6 4.3 1.9 8.2 4.3 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like rve PF00665.26 GBG66821.1 - 0.0032 17.7 0.0 0.0086 16.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF4535 PF15054.6 GBG66821.1 - 2 8.2 3.5 5.6 6.8 1.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) RVT_1 PF00078.27 GBG66822.1 - 9.2e-26 90.7 0.1 1.9e-25 89.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LysM PF01476.20 GBG66822.1 - 2e-08 34.2 0.1 7.4e-08 32.3 0.1 2.1 1 0 0 1 1 1 1 LysM domain CDH1_2_SANT_HL1 PF18375.1 GBG66822.1 - 0.15 12.8 0.0 0.87 10.3 0.0 2.3 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 Med4 PF10018.9 GBG66823.1 - 0.54 9.9 11.9 0.46 10.1 9.9 1.9 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Cob_adeno_trans PF01923.18 GBG66823.1 - 7 6.8 6.8 18 5.4 6.8 1.7 1 1 0 1 1 1 0 Cobalamin adenosyltransferase DUF501 PF04417.12 GBG66823.1 - 9.8 6.0 7.5 1.1 9.1 1.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF501) RVT_1 PF00078.27 GBG66824.1 - 6.9e-19 68.2 0.0 9.3e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP_N PF01213.19 GBG66825.1 - 6.1 6.2 12.3 9.7 5.6 10.6 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal RT_RNaseH PF17917.1 GBG66826.1 - 1.1e-21 77.0 0.0 2.3e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66826.1 - 2.8e-15 56.2 0.0 5.1e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66826.1 - 1.2e-13 50.9 0.0 2.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Tudor-knot PF11717.8 GBG66826.1 - 3.9e-05 23.4 0.0 8.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Nif11 PF07862.11 GBG66826.1 - 0.063 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Nif11 domain Vfa1 PF08432.10 GBG66827.1 - 8.7 6.6 10.6 11 6.3 10.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1764 PF08576.10 GBG66828.1 - 3.9e-20 72.6 10.1 3.9e-20 72.6 10.1 2.6 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) RVT_1 PF00078.27 GBG66829.1 - 2.7e-29 102.3 0.0 5.9e-29 101.2 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KH_7 PF17214.3 GBG66829.1 - 0.07 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 KH domain Mito_carr PF00153.27 GBG66831.1 - 9.1e-70 230.7 3.2 4.7e-24 84.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.6 GBG66832.1 - 2.6e-56 187.6 7.7 6e-16 58.4 0.0 9.9 3 1 8 11 11 11 9 PPR repeat family PPR_1 PF12854.7 GBG66832.1 - 9.3e-55 182.0 5.5 1.2e-08 34.4 0.2 9.5 8 1 1 9 9 9 8 PPR repeat PPR PF01535.20 GBG66832.1 - 5.8e-51 167.2 13.3 7.8e-07 28.9 0.1 10.2 10 0 0 10 10 10 8 PPR repeat PPR_3 PF13812.6 GBG66832.1 - 1.4e-39 134.0 1.9 2.6e-10 40.2 0.1 8.1 3 2 4 8 8 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG66832.1 - 1.3e-32 112.9 1.0 5.7e-13 48.7 0.0 3.6 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP RT_RNaseH_2 PF17919.1 GBG66832.1 - 2.7e-26 91.5 0.0 7.2e-26 90.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66832.1 - 5.8e-26 90.8 0.0 1.7e-25 89.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66832.1 - 2.7e-10 40.2 0.0 5.1e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66832.1 - 6.5e-05 23.0 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain MRP-S27 PF10037.9 GBG66832.1 - 0.005 15.8 0.0 0.005 15.8 0.0 4.8 4 1 1 5 5 3 1 Mitochondrial 28S ribosomal protein S27 SPOB_a PF14689.6 GBG66832.1 - 0.031 14.0 0.1 2.4 7.9 0.0 3.6 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain PPR_3 PF13812.6 GBG66833.1 - 1.3e-26 92.5 0.2 1.9e-10 40.7 0.0 4.0 1 1 3 4 4 4 4 Pentatricopeptide repeat domain PPR_2 PF13041.6 GBG66833.1 - 1.5e-26 92.3 2.0 2.5e-11 43.6 0.1 5.1 1 1 4 5 5 5 5 PPR repeat family PPR PF01535.20 GBG66833.1 - 2.5e-23 80.7 3.1 1e-05 25.5 0.7 5.5 5 0 0 5 5 5 4 PPR repeat PPR_1 PF12854.7 GBG66833.1 - 2.6e-19 68.6 0.7 5.9e-05 22.7 0.2 4.7 4 0 0 4 4 4 4 PPR repeat PPR_long PF17177.4 GBG66833.1 - 3.3e-15 56.0 0.3 2.1e-07 30.5 0.1 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP RRM_1 PF00076.22 GBG66833.1 - 7.5e-13 48.1 0.1 3.6e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECSIT PF06239.11 GBG66833.1 - 0.0047 16.1 0.1 0.19 10.8 0.0 2.2 1 1 1 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway RRM_7 PF16367.5 GBG66833.1 - 0.0087 16.2 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 GBG66833.1 - 0.019 14.8 0.0 0.19 11.6 0.0 2.2 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GBG66833.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MA3 PF02847.17 GBG66833.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 MA3 domain Apt1 PF10351.9 GBG66833.1 - 0.91 8.3 5.3 1.5 7.6 5.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 GBG66833.1 - 2.7 7.2 12.5 5 6.4 12.5 1.4 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 GBG66833.1 - 5.3 5.5 8.7 8.3 4.8 8.7 1.4 1 1 0 1 1 1 0 Macoilin family RVT_1 PF00078.27 GBG66834.1 - 1.7e-24 86.6 0.0 3.6e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66834.1 - 4.6e-20 71.5 0.4 2.1e-19 69.3 0.2 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG66834.1 - 1.8e-15 56.8 0.0 4.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66834.1 - 8.1e-09 35.7 0.0 9.5e-06 25.9 0.0 2.7 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG66834.1 - 7.5e-07 29.7 0.0 1.9e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66834.1 - 1.3e-05 25.6 0.0 3.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG66834.1 - 0.00087 19.1 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66834.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG66834.1 - 0.02 15.1 0.8 0.02 15.1 0.8 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG66834.1 - 0.022 15.0 0.0 0.062 13.5 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF1421 PF07223.11 GBG66835.1 - 1.6e-16 59.9 1.3 1.6e-16 59.9 1.3 2.2 2 0 0 2 2 2 1 UBA-like domain (DUF1421) Glyoxalase PF00903.25 GBG66835.1 - 0.012 15.8 0.0 0.96 9.6 0.0 2.9 3 1 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CdvA PF18822.1 GBG66835.1 - 0.012 15.4 1.9 0.054 13.3 0.1 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain WIYLD PF10440.9 GBG66835.1 - 0.036 13.9 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain RT_RNaseH PF17917.1 GBG66836.1 - 1e-30 106.1 0.1 2.4e-30 104.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66836.1 - 2.6e-28 98.0 0.0 6.7e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66836.1 - 2.5e-15 56.7 0.1 7.7e-15 55.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG66836.1 - 6.8e-08 32.5 0.4 1.7e-07 31.2 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Rrn6 PF10214.9 GBG66836.1 - 3.9 5.8 12.4 1 7.8 8.0 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor SNF2_N PF00176.23 GBG66837.1 - 1.8e-51 175.0 0.0 2.6e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG66837.1 - 8.1e-14 51.9 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG66837.1 - 3.1e-08 33.8 0.0 1.1e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG66837.1 - 0.00057 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase YL1 PF05764.13 GBG66837.1 - 0.0073 16.5 16.4 0.0073 16.5 16.4 2.9 3 0 0 3 3 3 1 YL1 nuclear protein DUF2075 PF09848.9 GBG66837.1 - 0.0082 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 GBG66837.1 - 0.045 13.4 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Peptidase_M17_N PF02789.17 GBG66837.1 - 0.046 13.6 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain TFIIF_alpha PF05793.12 GBG66837.1 - 6.1 5.3 57.4 3.6 6.1 19.2 2.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RT_RNaseH PF17917.1 GBG66838.1 - 4.6e-22 78.3 0.0 8.9e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66838.1 - 4.5e-21 74.8 0.0 1.7e-20 72.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG66838.1 - 6.1e-08 33.1 0.1 3.1e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG66838.1 - 3e-05 24.6 0.2 0.00052 20.6 0.0 2.7 3 0 0 3 3 3 1 Aspartyl protease Asp_protease PF09668.10 GBG66838.1 - 0.0021 17.8 0.6 0.0039 17.0 0.6 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG66838.1 - 0.013 15.8 0.0 0.041 14.2 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG66838.1 - 0.015 15.5 0.0 0.051 13.8 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Host_attach PF10116.9 GBG66838.1 - 0.25 11.9 5.3 0.97 10.0 5.3 2.1 1 0 0 1 1 1 0 Protein required for attachment to host cells BNIP3 PF06553.12 GBG66838.1 - 4 7.1 5.7 9.4 5.9 5.7 1.5 1 0 0 1 1 1 0 BNIP3 N6_N4_Mtase PF01555.18 GBG66839.1 - 0.0083 15.9 0.0 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 DNA methylase Nop14 PF04147.12 GBG66839.1 - 0.17 10.1 15.1 0.3 9.2 15.1 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG66839.1 - 0.38 9.0 8.2 0.65 8.2 8.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Ldl_recept_a PF00057.18 GBG66840.1 - 1.9e-27 95.2 36.7 1.1e-09 38.3 7.2 3.8 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Pkinase_Tyr PF07714.17 GBG66840.1 - 2.9e-24 85.7 0.0 4.2e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG66840.1 - 2.1e-23 83.1 0.0 1.6e-13 50.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG66840.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PRKCSH-like PF12999.7 GBG66840.1 - 0.22 11.3 29.0 0.28 11.0 14.1 2.3 1 1 1 2 2 2 0 Glucosidase II beta subunit-like BatA PF07584.11 GBG66840.1 - 0.32 11.4 2.4 2.1 8.7 1.8 2.2 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal CUE PF02845.16 GBG66841.1 - 3e-06 26.8 0.3 3e-06 26.8 0.3 2.0 2 0 0 2 2 2 1 CUE domain UPF0242 PF06785.11 GBG66841.1 - 0.0016 18.6 2.1 0.0025 17.9 2.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 GBG66841.1 - 0.0098 15.0 6.1 0.015 14.4 6.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 GBG66841.1 - 0.044 14.0 2.5 0.082 13.1 2.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Yuri_gagarin PF15934.5 GBG66841.1 - 0.055 13.3 2.5 0.094 12.6 2.5 1.3 1 0 0 1 1 1 0 Yuri gagarin DUF5384 PF17358.2 GBG66841.1 - 0.081 13.0 7.1 0.15 12.1 6.5 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5384) GAS PF13851.6 GBG66841.1 - 0.085 12.2 14.9 0.079 12.3 12.7 2.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 GBG66841.1 - 0.1 13.2 5.2 0.1 13.2 3.1 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.21 GBG66841.1 - 0.11 12.7 4.0 0.41 10.8 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 GBG66841.1 - 0.15 12.4 4.5 4.9 7.6 0.4 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family Cnn_1N PF07989.11 GBG66841.1 - 0.56 10.4 9.5 1.4 9.2 0.4 2.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Fes1 PF08609.10 GBG66841.1 - 1.3 9.9 4.1 5.1 8.0 4.1 2.1 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 YabA PF06156.13 GBG66841.1 - 2 9.1 9.9 7.3 7.3 2.1 2.7 2 1 1 3 3 2 0 Initiation control protein YabA ZapB PF06005.12 GBG66841.1 - 3.4 8.2 13.1 1.8e+02 2.6 13.1 2.6 1 1 0 1 1 1 0 Cell division protein ZapB Swi5 PF07061.11 GBG66841.1 - 3.6 7.7 11.9 2.2 8.4 4.1 2.6 1 1 1 2 2 2 0 Swi5 ATG16 PF08614.11 GBG66841.1 - 3.7 7.7 14.7 6.7 6.9 14.6 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.15 GBG66841.1 - 5 7.3 12.5 7.1 6.8 0.3 2.6 1 1 0 2 2 2 0 Basic region leucine zipper Snf7 PF03357.21 GBG66842.1 - 6e-31 107.3 11.2 6e-31 107.3 11.2 2.4 2 1 0 2 2 2 1 Snf7 TMV_coat PF00721.21 GBG66842.1 - 2.6 7.8 8.0 4.3 7.1 0.7 2.9 3 0 0 3 3 3 0 Virus coat protein (TMV like) zf-ribbon_3 PF13248.6 GBG66843.1 - 0.00087 18.6 0.8 0.0016 17.8 0.8 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 GBG66843.1 - 0.0015 18.5 0.3 0.0046 16.9 0.3 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 GBG66843.1 - 0.016 14.9 3.9 0.051 13.3 3.9 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 GBG66843.1 - 0.36 11.6 0.1 0.36 11.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon family Nudix_N_2 PF14803.6 GBG66843.1 - 0.76 9.8 3.8 17 5.4 0.2 2.7 2 0 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.6 GBG66844.1 - 0.00088 18.6 0.8 0.0017 17.7 0.8 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 GBG66844.1 - 0.0016 18.5 0.3 0.0049 16.9 0.3 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 GBG66844.1 - 0.017 14.8 3.9 0.052 13.3 3.9 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 GBG66844.1 - 0.37 11.6 0.1 0.37 11.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon family Nudix_N_2 PF14803.6 GBG66844.1 - 0.8 9.7 3.8 18 5.4 0.2 2.7 2 0 0 2 2 2 0 Nudix N-terminal Hamartin PF04388.12 GBG66845.1 - 6.8 5.2 11.0 7.8 5.0 11.0 1.1 1 0 0 1 1 1 0 Hamartin protein SCAB-PH PF17684.1 GBG66847.1 - 2.3e-36 124.3 0.0 4.8e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 PH domain of plant-specific actin-binding protein SCAB_CC PF16712.5 GBG66847.1 - 1.1e-33 116.5 19.2 1.6e-33 115.9 19.2 1.2 1 0 0 1 1 1 1 Coiled-coil regions of plant-specific actin-binding protein SCAB-Ig PF16709.5 GBG66847.1 - 1.5e-23 82.7 0.0 3.5e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Ig domain of plant-specific actin-binding protein SCAB-ABD PF16711.5 GBG66847.1 - 2.5e-12 46.5 6.4 9.7e-12 44.6 0.3 2.5 2 0 0 2 2 2 1 Actin-binding domain of plant-specific actin-binding protein DUF883 PF05957.13 GBG66847.1 - 1.3 9.7 8.5 1.9 9.1 6.2 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) RVT_1 PF00078.27 GBG66849.1 - 8.5e-10 38.5 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG66849.1 - 0.00018 22.0 0.0 0.00055 20.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG66849.1 - 0.0039 17.5 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG66849.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG66849.1 - 0.02 15.5 0.0 0.057 14.1 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease PikAIV_N PF18605.1 GBG66849.1 - 0.076 12.6 0.9 0.17 11.5 0.9 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Mito_carr PF00153.27 GBG66850.1 - 2.6e-61 203.5 0.2 7.5e-20 70.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein QWRF PF04484.12 GBG66850.1 - 2.6 7.7 6.6 3.9 7.1 6.6 1.2 1 0 0 1 1 1 0 QWRF family zf-C3HC4_2 PF13923.6 GBG66852.1 - 3.9e-11 42.6 9.7 7.4e-11 41.7 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG66852.1 - 8.4e-09 35.2 8.5 1.9e-08 34.0 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG66852.1 - 1.6e-08 34.3 10.0 1.6e-08 34.3 10.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GBG66852.1 - 1.9e-08 34.5 8.4 4.3e-08 33.4 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG66852.1 - 2.1e-08 33.9 11.3 2.1e-08 33.9 11.3 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG66852.1 - 8e-07 29.1 7.7 2e-06 27.8 7.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GBG66852.1 - 6.8e-06 25.8 8.2 6.8e-06 25.8 8.2 1.8 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GBG66852.1 - 7.1e-06 26.0 7.5 1.6e-05 24.9 7.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GBG66852.1 - 5.4e-05 23.4 4.8 0.00019 21.7 4.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 GBG66852.1 - 0.0003 20.9 6.3 0.0003 20.9 6.3 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 GBG66852.1 - 0.0012 18.6 7.6 0.003 17.3 7.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 GBG66852.1 - 0.016 15.0 4.2 0.03 14.1 4.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 GBG66852.1 - 0.041 13.8 2.7 0.11 12.4 2.7 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn-ribbon_8 PF09723.10 GBG66852.1 - 0.24 11.6 2.4 0.65 10.2 2.4 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 GBG66852.1 - 7.8 6.6 13.6 0.2 11.7 6.4 2.1 2 0 0 2 2 2 0 Double zinc ribbon DUF659 PF04937.15 GBG66853.1 - 1.8e-05 24.7 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF1660 PF07874.11 GBG66853.1 - 1.3 9.6 4.9 2.8 8.5 4.9 1.5 1 0 0 1 1 1 0 Prophage protein (DUF1660) zf-CCHC PF00098.23 GBG66854.1 - 0.00056 19.9 6.2 0.00056 19.9 6.2 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG66854.1 - 0.00084 19.2 2.8 0.0031 17.4 2.8 1.9 1 0 0 1 1 1 1 Zinc knuckle CobN-Mg_chel PF02514.16 GBG66854.1 - 0.0028 15.5 1.5 0.0031 15.3 1.5 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase SWI-SNF_Ssr4 PF08549.10 GBG66854.1 - 0.26 9.9 10.1 0.34 9.5 10.1 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) zf-CCHC_2 PF13696.6 GBG66854.1 - 0.48 10.3 8.6 0.95 9.4 5.3 2.2 2 0 0 2 2 2 0 Zinc knuckle LMBR1 PF04791.16 GBG66854.1 - 0.74 8.6 5.4 0.95 8.3 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RR_TM4-6 PF06459.12 GBG66854.1 - 1.9 8.3 13.1 2.8 7.7 13.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 GBG66854.1 - 3.6 6.0 20.5 4.6 5.6 20.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.25 GBG66855.1 - 8.6e-75 251.5 0.0 2e-74 250.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain EF-hand_1 PF00036.32 GBG66855.1 - 5.6e-34 113.2 5.8 7.7e-08 31.3 0.3 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.17 GBG66855.1 - 1e-27 97.1 0.0 5e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GBG66855.1 - 4.9e-27 94.2 1.2 6.4e-13 49.0 0.8 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG66855.1 - 4.4e-26 88.5 3.3 6.4e-07 28.8 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GBG66855.1 - 7.9e-23 80.1 7.8 7.5e-08 32.1 0.0 4.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GBG66855.1 - 2.9e-22 77.1 2.4 7.5e-06 25.2 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 GBG66855.1 - 3.7e-10 39.7 0.2 6.9e-05 22.7 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 GBG66855.1 - 5.9e-07 29.7 0.1 0.0078 16.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.14 GBG66855.1 - 3.2e-06 26.6 0.0 6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 GBG66855.1 - 8.3e-06 26.1 0.1 0.0082 16.4 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 GBG66855.1 - 1.2e-05 24.8 0.0 3.9e-05 23.1 0.0 2.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 GBG66855.1 - 0.00064 19.7 0.0 0.55 10.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF5580 PF17743.1 GBG66855.1 - 0.18 10.3 0.0 0.82 8.1 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5580) LETM1 PF07766.13 GBG66856.1 - 0.28 10.5 2.9 0.41 9.9 2.9 1.2 1 0 0 1 1 1 0 LETM1-like protein DUF1664 PF07889.12 GBG66856.1 - 0.93 9.5 3.8 6.9 6.7 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GP41 PF00517.17 GBG66856.1 - 3 7.7 5.3 2.2 8.1 0.2 2.2 1 1 1 2 2 2 0 Retroviral envelope protein TFIID_20kDa PF03847.13 GBG66857.1 - 2.5e-27 95.2 0.1 4.6e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A UreF PF01730.16 GBG66858.1 - 1e-21 77.9 0.5 1.8e-21 77.1 0.5 1.4 1 0 0 1 1 1 1 UreF Patched PF02460.18 GBG66859.1 - 1.6e-87 294.5 19.9 2.6e-54 184.6 0.1 2.2 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 GBG66859.1 - 7.6e-64 215.6 4.6 1.4e-63 214.7 4.6 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 GBG66859.1 - 1.5e-49 167.8 9.6 1.5e-49 167.8 9.6 2.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 GBG66859.1 - 0.0014 17.7 10.6 0.0014 17.7 10.6 2.5 2 0 0 2 2 2 1 MMPL family DUF5066 PF16728.5 GBG66859.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) V_ATPase_I PF01496.19 GBG66860.1 - 0.086 10.7 3.0 0.12 10.3 3.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3972 PF13118.6 GBG66860.1 - 0.21 12.0 6.9 0.19 12.2 5.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Csm1_N PF18504.1 GBG66860.1 - 0.76 10.2 10.1 3.1 8.2 0.9 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF3450 PF11932.8 GBG66860.1 - 3.4 6.9 11.3 5.5 6.2 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pox_RNA_pol PF03293.14 GBG66861.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Com_YlbF PF06133.11 GBG66861.1 - 0.12 13.0 8.9 1.8 9.2 3.5 2.5 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Talin_middle PF09141.10 GBG66861.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.2 3 0 0 3 3 3 0 Talin, middle domain DUF2203 PF09969.9 GBG66861.1 - 1.7 9.4 9.4 0.17 12.6 4.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) NAM-associated PF14303.6 GBG66861.1 - 3.7 8.3 8.9 9.6 6.9 7.8 2.0 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain SAM_1 PF00536.30 GBG66863.1 - 3.4e-12 46.6 0.0 7.3e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GBG66863.1 - 1.5e-09 37.8 0.0 2.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RT_RNaseH PF17917.1 GBG66864.1 - 4.1e-18 65.6 0.0 8e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66864.1 - 1.4e-15 57.1 0.0 3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SRP-alpha_N PF04086.13 GBG66864.1 - 0.077 12.9 7.9 0.15 12.0 7.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SIR2 PF02146.17 GBG66865.1 - 1.2e-26 93.7 0.4 3.8e-10 40.0 0.1 3.3 2 1 1 3 3 3 3 Sir2 family Seipin PF06775.14 GBG66868.1 - 3.4e-38 131.7 0.0 5.5e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) COPIIcoated_ERV PF07970.12 GBG66871.1 - 7.9e-44 150.1 0.1 1.2e-43 149.6 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GBG66871.1 - 8.9e-26 90.1 0.0 1.7e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) UCR_Fe-S_N PF10399.9 GBG66871.1 - 0.061 12.7 0.5 0.11 11.8 0.5 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DOMON PF03351.17 GBG66872.1 - 7.5e-11 42.3 0.0 1.6e-06 28.3 0.1 2.3 2 0 0 2 2 2 2 DOMON domain Cytochrom_B561 PF03188.16 GBG66872.1 - 7e-06 26.2 3.2 1.5e-05 25.2 3.2 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 TFIIIC_delta PF12657.7 GBG66872.1 - 0.0042 17.0 1.0 2.9 7.8 0.1 2.5 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term DUF2427 PF10348.9 GBG66872.1 - 0.031 14.1 2.1 0.077 12.8 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) PK PF00224.21 GBG66873.1 - 5.8e-156 518.7 1.3 5.8e-156 518.7 1.3 1.4 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG66873.1 - 9.8e-23 80.6 1.1 2.7e-22 79.2 0.3 2.2 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GBG66873.1 - 0.0022 17.2 0.4 0.0076 15.4 0.3 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PcrB PF01884.17 GBG66873.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 PcrB family PA26 PF04636.13 GBG66874.1 - 0.05 12.5 1.5 0.071 12.0 1.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4192 PF13830.6 GBG66874.1 - 0.062 13.3 1.4 0.099 12.7 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Rx_N PF18052.1 GBG66874.1 - 0.48 10.7 13.5 0.12 12.6 7.9 2.8 3 0 0 3 3 3 0 Rx N-terminal domain LMBR1 PF04791.16 GBG66874.1 - 0.83 8.5 2.4 0.89 8.4 2.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ebp2 PF05890.12 GBG66874.1 - 6.7 6.2 23.8 11 5.5 23.8 1.3 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 V_ATPase_I PF01496.19 GBG66874.1 - 9.4 4.0 8.5 11 3.8 8.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNB PF00773.19 GBG66875.1 - 1.6e-53 182.2 0.0 3.3e-53 181.2 0.0 1.5 2 0 0 2 2 2 1 RNB domain VID27_PH PF17747.1 GBG66875.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 VID27 PH-like domain SAPS PF04499.15 GBG66876.1 - 0.31 9.8 10.1 0.29 9.9 10.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 GBG66876.1 - 0.47 8.5 8.4 0.46 8.6 8.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 GBG66876.1 - 0.89 8.5 8.4 0.93 8.4 8.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 GBG66876.1 - 3.2 6.4 14.9 3.5 6.3 14.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PA26 PF04636.13 GBG66876.1 - 3.9 6.3 9.8 4 6.3 9.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RVT_1 PF00078.27 GBG66877.1 - 2.8e-34 118.6 0.1 4.6e-34 117.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66877.1 - 5.9e-15 55.1 0.1 2e-14 53.4 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66877.1 - 1.1e-14 54.7 0.0 2.4e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG66877.1 - 3e-07 30.3 0.0 6.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG66877.1 - 0.00098 19.7 0.0 0.0027 18.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG66877.1 - 0.0038 17.4 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG66877.1 - 0.0047 17.5 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG66877.1 - 0.0084 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease eIF-1a PF01176.19 GBG66877.1 - 0.021 14.6 0.1 0.052 13.4 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 rve_3 PF13683.6 GBG66877.1 - 0.075 12.8 0.0 0.33 10.8 0.0 2.2 1 0 0 1 1 1 0 Integrase core domain bZIP_2 PF07716.15 GBG66877.1 - 0.87 9.7 10.6 0.35 11.0 4.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper ubiquitin PF00240.23 GBG66878.1 - 1.1e-33 114.7 0.4 2.1e-33 113.9 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 GBG66878.1 - 1.5e-25 89.0 1.3 1.5e-25 89.0 1.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 GBG66878.1 - 2.8e-16 59.1 0.8 2.8e-16 59.1 0.8 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GBG66878.1 - 7.8e-05 23.1 1.5 0.00026 21.4 0.1 2.4 2 2 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GBG66878.1 - 0.00047 20.2 0.8 0.001 19.2 0.8 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GBG66878.1 - 0.006 17.1 0.9 0.0085 16.6 0.9 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 GBG66878.1 - 0.0072 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GBG66878.1 - 0.012 16.0 1.8 0.012 15.9 0.1 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 GBG66878.1 - 0.047 13.7 1.1 9.2 6.4 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Plexin_cytopl PF08337.12 GBG66878.1 - 0.25 10.0 3.1 2.5 6.6 0.2 2.6 2 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain RPN2_C PF18004.1 GBG66879.1 - 4.2e-45 153.5 0.2 4.2e-45 153.5 0.2 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 GBG66879.1 - 4.6e-25 86.7 34.1 1.7e-05 25.0 0.5 9.4 10 1 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GBG66879.1 - 8.3e-15 55.0 4.1 3.9e-12 46.4 0.3 4.7 5 0 0 5 5 5 1 HEAT repeats RPN1_RPN2_N PF17781.1 GBG66879.1 - 1.5e-07 31.1 1.4 3.3e-07 30.0 1.4 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain HEAT_EZ PF13513.6 GBG66879.1 - 0.00096 19.6 3.6 0.075 13.6 0.1 4.3 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 GBG66879.1 - 0.0079 16.4 2.9 2.1 8.8 0.1 4.7 4 0 0 4 4 4 1 HEAT repeat HEAT_PBS PF03130.16 GBG66879.1 - 0.12 13.1 2.6 30 5.7 0.0 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat TIP49 PF06068.13 GBG66880.1 - 6.1e-133 443.4 4.9 1.2e-124 416.0 1.7 2.1 1 1 1 2 2 2 2 TIP49 P-loop domain TIP49_C PF17856.1 GBG66880.1 - 1.8e-20 72.8 0.1 5e-20 71.4 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 GBG66880.1 - 4e-07 29.9 0.0 7.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 GBG66880.1 - 9e-07 29.4 0.1 1.8e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GBG66880.1 - 0.0026 18.0 0.2 0.0073 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 GBG66880.1 - 0.006 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_19 PF13245.6 GBG66880.1 - 0.013 15.9 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GBG66880.1 - 0.013 15.9 0.1 0.026 14.9 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 GBG66880.1 - 0.014 14.9 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GBG66880.1 - 0.023 14.0 0.3 0.065 12.5 0.3 1.7 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 GBG66880.1 - 0.029 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GBG66880.1 - 0.036 14.0 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 GBG66880.1 - 0.05 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 GBG66880.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GBG66880.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 GBG66881.1 - 6.1e-133 443.4 4.9 1.2e-124 416.0 1.7 2.1 1 1 1 2 2 2 2 TIP49 P-loop domain TIP49_C PF17856.1 GBG66881.1 - 1.8e-20 72.8 0.1 5e-20 71.4 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 GBG66881.1 - 4e-07 29.9 0.0 7.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 GBG66881.1 - 9e-07 29.4 0.1 1.8e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GBG66881.1 - 0.0026 18.0 0.2 0.0073 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 GBG66881.1 - 0.006 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_19 PF13245.6 GBG66881.1 - 0.013 15.9 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GBG66881.1 - 0.013 15.9 0.1 0.026 14.9 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 GBG66881.1 - 0.014 14.9 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GBG66881.1 - 0.023 14.0 0.3 0.065 12.5 0.3 1.7 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 GBG66881.1 - 0.029 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GBG66881.1 - 0.036 14.0 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 GBG66881.1 - 0.05 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 GBG66881.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GBG66881.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PsbP PF01789.16 GBG66882.1 - 1.5e-47 161.6 1.3 2.1e-47 161.2 1.3 1.2 1 0 0 1 1 1 1 PsbP C2 PF00168.30 GBG66883.1 - 3.9e-78 258.4 0.1 2.6e-18 66.2 0.0 4.3 4 0 0 4 4 4 4 C2 domain PRT_C PF08372.10 GBG66883.1 - 3e-27 95.3 0.2 6.6e-27 94.2 0.2 1.6 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 GBG66883.1 - 0.0052 16.7 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 1 Reticulon Pex24p PF06398.11 GBG66883.1 - 0.029 13.3 2.3 0.068 12.1 1.5 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin KleE PF17394.2 GBG66883.1 - 0.071 13.3 0.2 0.22 11.8 0.2 1.8 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein Nop14 PF04147.12 GBG66884.1 - 0.5 8.5 5.6 0.61 8.2 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 GBG66887.1 - 0.028 14.7 27.9 0.037 14.3 27.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 GBG66887.1 - 0.071 12.4 20.4 0.083 12.2 20.4 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GBG66887.1 - 0.12 10.6 24.3 0.11 10.7 24.3 1.0 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 GBG66887.1 - 0.58 9.7 21.5 0.63 9.5 21.5 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein NPR3 PF03666.13 GBG66887.1 - 8 5.1 20.2 8.9 5.0 20.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 O-FucT PF10250.9 GBG66888.1 - 4.2e-11 43.1 1.0 7.7e-09 35.7 1.0 3.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TPR_15 PF13429.6 GBG66888.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_C48 PF02902.19 GBG66889.1 - 1.7e-18 67.2 0.4 1.7e-18 67.2 0.4 2.1 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Plavaka PF18759.1 GBG66889.1 - 3.6e-12 46.2 0.4 8.4e-12 44.9 0.4 1.5 1 0 0 1 1 1 1 Plavaka transposase Mt_ATP_synt PF15704.5 GBG66891.1 - 3.7e-49 167.2 11.5 4.7e-49 166.8 11.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase subunit Mitofilin PF09731.9 GBG66891.1 - 0.0035 16.3 5.9 0.0044 15.9 5.9 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4897 PF16238.5 GBG66891.1 - 0.049 13.5 2.0 0.055 13.3 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) Glyco_hydro_77 PF02446.17 GBG66891.1 - 0.068 12.0 1.0 0.1 11.5 0.6 1.4 1 1 0 1 1 1 0 4-alpha-glucanotransferase DUF148 PF02520.17 GBG66891.1 - 0.13 12.4 6.9 0.042 14.0 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 TMPIT PF07851.13 GBG66891.1 - 0.42 9.8 3.9 4.5 6.4 1.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein PCRF PF03462.18 GBG66891.1 - 0.9 9.4 8.3 1.3 8.9 5.0 2.1 2 0 0 2 2 2 0 PCRF domain HisKA_3 PF07730.13 GBG66891.1 - 4 8.0 8.0 11 6.7 0.0 3.7 4 1 0 4 4 4 0 Histidine kinase DUF4164 PF13747.6 GBG66891.1 - 4.7 7.5 9.1 11 6.4 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) ABA_GPCR PF12430.8 GBG66892.1 - 1.1e-40 139.4 4.9 1.1e-40 139.4 4.9 2.4 3 0 0 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 GBG66892.1 - 5.4e-20 71.2 1.0 2.2e-19 69.3 0.0 2.5 3 0 0 3 3 3 1 The Golgi pH Regulator (GPHR) Family N-terminal LMBR1 PF04791.16 GBG66892.1 - 6.5e-06 25.3 1.5 2.4e-05 23.5 1.4 2.1 1 1 0 1 1 1 1 LMBR1-like membrane protein UPF0242 PF06785.11 GBG66892.1 - 0.00014 22.1 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 GBG66892.1 - 0.0037 17.7 4.6 0.0046 17.4 1.4 2.2 2 0 0 2 2 2 1 Cell division protein ZapB GAS PF13851.6 GBG66892.1 - 0.0087 15.4 0.6 0.014 14.7 0.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TEX13 PF15186.6 GBG66892.1 - 0.037 13.7 2.4 0.063 13.0 0.6 2.0 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family APG6_N PF17675.1 GBG66892.1 - 0.061 13.9 2.3 0.1 13.2 2.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Ax_dynein_light PF10211.9 GBG66892.1 - 0.16 11.9 2.7 0.78 9.7 0.9 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Med4 PF10018.9 GBG66892.1 - 0.18 11.4 0.4 0.28 10.8 0.4 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 IBR PF01485.21 GBG66893.1 - 9.6e-09 35.3 39.6 5e-07 29.8 3.3 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain Myb_DNA-bind_4 PF13837.6 GBG66894.1 - 1.6e-08 34.8 4.8 2.5e-08 34.2 2.3 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG66894.1 - 0.00033 20.9 2.6 0.0051 17.1 0.5 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG66894.1 - 0.004 17.3 1.1 0.0093 16.1 1.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG66894.1 - 0.0048 16.9 0.8 0.014 15.4 0.8 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain WRC PF08879.10 GBG66896.1 - 1.3e-10 40.8 0.3 1.3e-10 40.8 0.3 3.7 3 0 0 3 3 3 2 WRC RFamide_26RFa PF11109.8 GBG66896.1 - 5.5 7.5 7.4 2.9 8.4 3.6 2.6 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 RVT_1 PF00078.27 GBG66897.1 - 0.074 12.5 0.0 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lipoprotein_18 PF06804.11 GBG66897.1 - 2.6 7.0 5.1 4.2 6.3 5.1 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Mei4 PF13971.6 GBG66900.1 - 0.017 14.6 1.8 0.021 14.4 1.8 1.2 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 DUF4288 PF14119.6 GBG66900.1 - 0.063 13.7 3.9 0.13 12.7 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) zf-CCHC PF00098.23 GBG66901.1 - 1.1e-05 25.2 4.4 1.1e-05 25.2 4.4 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG66901.1 - 0.0042 16.9 3.9 0.0042 16.9 3.9 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG66901.1 - 0.55 10.2 6.1 1.6 8.8 6.1 1.9 1 1 0 1 1 1 0 Zinc knuckle Atg14 PF10186.9 GBG66901.1 - 0.69 8.9 9.1 0.69 8.9 9.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3492 PF11997.8 GBG66901.1 - 1.1 8.9 5.0 1.6 8.4 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) XRN_M PF17846.1 GBG66901.1 - 3.8 6.4 8.5 5.2 5.9 8.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain LMBR1 PF04791.16 GBG66901.1 - 4.2 6.2 5.2 5.3 5.8 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 GBG66901.1 - 4.5 5.8 9.4 6.2 5.3 9.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 GBG66901.1 - 4.6 7.3 13.3 7.6 6.6 13.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SAM_decarbox PF01536.16 GBG66902.1 - 7.2e-99 331.2 0.0 8.3e-99 330.9 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Ntox50 PF15542.6 GBG66904.1 - 0.0045 17.8 1.3 0.23 12.3 0.8 2.7 2 0 0 2 2 2 2 Bacterial toxin 50 RVT_1 PF00078.27 GBG66906.1 - 3.8e-77 258.7 2.5 4.9e-35 121.1 0.1 3.6 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66906.1 - 1.1e-66 221.1 0.0 4.1e-26 90.9 0.0 4.3 4 0 0 4 4 4 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66906.1 - 6.6e-52 174.2 0.0 2e-27 95.5 0.1 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG66906.1 - 5.4e-10 39.2 1.1 1.4e-09 37.9 1.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Lactamase_B_6 PF16661.5 GBG66906.1 - 2.1e-07 30.6 0.1 0.00026 20.5 0.0 2.9 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 GBG66906.1 - 3.7e-07 30.4 0.0 1.3e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Beta-Casp domain Retrotrans_gag PF03732.17 GBG66906.1 - 0.00036 20.7 0.0 0.041 14.1 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein RACo_linker PF17650.1 GBG66906.1 - 0.04 13.8 1.4 17 5.3 0.1 3.4 3 0 0 3 3 3 0 RACo linker region DUF4187 PF13821.6 GBG66906.1 - 0.078 12.8 0.4 0.34 10.7 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RT_RNaseH_2 PF17919.1 GBG66908.1 - 3.9e-63 209.7 0.1 2.4e-28 98.1 0.0 3.9 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66908.1 - 1e-56 189.7 0.1 6.3e-27 93.9 0.1 3.9 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66908.1 - 8.9e-39 132.4 0.2 2.5e-12 47.0 0.1 3.9 3 0 0 3 3 3 3 Integrase core domain Integrase_H2C2 PF17921.1 GBG66908.1 - 1.1e-31 108.7 0.6 1.8e-14 53.6 0.0 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG66908.1 - 1.3e-28 100.1 0.1 2.9e-28 98.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG66908.1 - 0.00032 20.8 0.3 0.0074 16.5 0.0 3.0 2 0 0 2 2 2 1 H2C2 zinc finger Peptidase_C39 PF03412.15 GBG66908.1 - 0.011 15.6 0.2 30 4.4 0.0 3.9 3 0 0 3 3 3 0 Peptidase C39 family Mcp5_PH PF12814.7 GBG66908.1 - 0.16 12.1 4.2 5.9 7.0 0.3 2.9 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology RT_RNaseH PF17917.1 GBG66909.1 - 1.4e-27 96.0 0.1 2.3e-27 95.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66909.1 - 1.5e-25 89.2 0.0 2.4e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glyco_tranf_2_4 PF13704.6 GBG66909.1 - 0.029 14.9 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Dynein_light PF01221.18 GBG66910.1 - 1.8e-22 79.5 0.2 2.7e-22 78.9 0.2 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 ClpB_D2-small PF10431.9 GBG66910.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein RT_RNaseH_2 PF17919.1 GBG66911.1 - 8.4e-21 73.9 0.0 1.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66911.1 - 4.4e-18 65.5 0.0 6.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66912.1 - 8.9e-51 170.6 0.2 4.5e-24 84.7 0.8 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66912.1 - 1.8e-44 149.8 0.0 1.8e-25 88.9 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase DUF4661 PF15576.6 GBG66912.1 - 0.25 11.2 0.7 0.45 10.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Phage_hub_GP28 PF11110.8 GBG66913.1 - 0.037 13.9 0.1 0.058 13.3 0.1 1.2 1 0 0 1 1 1 0 Baseplate hub distal subunit DDE_Tnp_4 PF13359.6 GBG66914.1 - 2.4e-15 56.6 0.0 3.9e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66914.1 - 1.5e-05 24.7 0.0 3.2e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66914.1 - 0.088 12.4 0.0 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 Transposase DDE domain DDHD PF02862.17 GBG66916.1 - 0.0093 16.1 0.5 0.01 16.0 0.5 1.2 1 0 0 1 1 1 1 DDHD domain Presenilin PF01080.17 GBG66916.1 - 0.016 14.0 13.6 0.018 13.8 13.6 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG66916.1 - 0.17 10.2 23.6 0.2 9.9 23.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Keratin_2_head PF16208.5 GBG66916.1 - 0.26 11.4 13.9 0.37 10.9 13.9 1.2 1 0 0 1 1 1 0 Keratin type II head DUF4366 PF14283.6 GBG66916.1 - 2.8 8.0 11.2 13 5.8 11.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) AAA_11 PF13086.6 GBG66916.1 - 3.6 7.3 12.7 4.9 6.9 12.7 1.2 1 0 0 1 1 1 0 AAA domain NPR3 PF03666.13 GBG66916.1 - 4.9 5.8 23.3 6.1 5.5 23.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RT_RNaseH PF17917.1 GBG66918.1 - 6.5e-29 100.3 0.0 2.6e-28 98.4 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG66918.1 - 9.2e-27 93.0 0.0 4.2e-26 90.9 0.0 2.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG66918.1 - 1.2e-09 38.4 0.1 4.1e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain AF-4 PF05110.13 GBG66919.1 - 2.3 6.2 73.6 3.3 5.7 73.6 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4378 PF14309.6 GBG66920.1 - 1.9e-31 109.7 0.4 3e-31 109.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) MoaE PF02391.17 GBG66922.1 - 7.4e-37 126.1 0.3 1e-36 125.7 0.3 1.2 1 0 0 1 1 1 1 MoaE protein RWP-RK PF02042.15 GBG66922.1 - 0.065 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 RWP-RK domain DUF3138 PF11336.8 GBG66924.1 - 6.5 5.2 7.5 2.7 6.5 3.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) HsbA PF12296.8 GBG66924.1 - 9.4 6.7 10.0 3.8 8.0 0.6 3.2 3 1 0 3 3 3 0 Hydrophobic surface binding protein A Retrotrans_gag PF03732.17 GBG66925.1 - 2.4e-05 24.5 5.6 0.0001 22.5 0.1 3.4 3 1 0 3 3 3 1 Retrotransposon gag protein SNAPc19 PF15497.6 GBG66925.1 - 0.015 15.7 4.3 1.2 9.6 0.0 3.2 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF3006 PF11213.8 GBG66925.1 - 0.026 14.7 1.3 0.066 13.4 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) RNR_Alpha PF17975.1 GBG66925.1 - 0.042 14.3 0.2 0.11 13.0 0.1 1.7 1 1 0 1 1 1 0 Ribonucleotide reductase alpha domain RVT_1 PF00078.27 GBG66926.1 - 4.7e-27 95.0 0.0 6.3e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66926.1 - 8.5e-24 83.5 0.0 1.5e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66926.1 - 1.9e-14 53.8 0.0 8e-14 51.8 0.0 2.0 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG66926.1 - 0.0067 15.6 0.0 0.011 14.9 0.0 1.3 1 1 0 1 1 1 1 Autophagy protein Apg17 DUF702 PF05142.12 GBG66927.1 - 5.5e-30 104.8 0.0 1.2e-29 103.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF702) RT_RNaseH_2 PF17919.1 GBG66927.1 - 1.3e-28 99.0 0.0 6.1e-14 51.9 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66927.1 - 3.7e-27 94.7 0.0 1e-26 93.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66927.1 - 1.4e-22 80.3 0.0 2.5e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG66927.1 - 1.8e-15 56.8 0.2 5.7e-15 55.2 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG66927.1 - 5e-12 45.5 0.0 1.3e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG66927.1 - 0.0007 19.8 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG66927.1 - 0.0023 18.1 0.0 0.008 16.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain SDA1 PF05285.12 GBG66927.1 - 0.02 14.4 39.0 0.032 13.6 39.0 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG66927.1 - 0.069 11.4 33.8 0.11 10.7 33.8 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG66927.1 - 1.7 6.9 26.5 2.9 6.1 26.5 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG66927.1 - 1.8 7.9 34.6 2.7 7.2 34.6 1.2 1 0 0 1 1 1 0 BUD22 RPOL_N PF14700.6 GBG66928.1 - 0.01 15.3 12.0 0.011 15.1 12.0 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal HemX PF04375.14 GBG66928.1 - 0.013 14.9 4.0 0.013 14.8 4.0 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase AAA_11 PF13086.6 GBG66928.1 - 0.013 15.3 10.4 0.015 15.1 10.4 1.0 1 0 0 1 1 1 0 AAA domain CPSF100_C PF13299.6 GBG66928.1 - 0.014 15.6 10.1 0.016 15.4 10.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NPR3 PF03666.13 GBG66928.1 - 0.022 13.6 14.5 0.022 13.6 14.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Protocadherin PF08374.11 GBG66928.1 - 0.033 14.2 13.6 0.047 13.7 13.6 1.3 1 0 0 1 1 1 0 Protocadherin CBP_BcsG PF11658.8 GBG66928.1 - 0.034 12.5 0.9 0.038 12.4 0.9 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG GNAT_acetyltr_2 PF13718.6 GBG66928.1 - 0.04 13.3 6.0 0.044 13.2 6.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RNA_polI_A34 PF08208.11 GBG66928.1 - 0.046 13.8 35.8 0.054 13.6 35.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Connexin PF00029.19 GBG66928.1 - 0.054 13.3 15.3 0.063 13.0 15.3 1.0 1 0 0 1 1 1 0 Connexin Dzip-like_N PF13815.6 GBG66928.1 - 0.065 13.2 9.9 0.086 12.8 9.9 1.2 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF1168 PF06658.12 GBG66928.1 - 0.069 13.0 34.1 0.089 12.6 34.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CLN3 PF02487.17 GBG66928.1 - 0.072 12.1 4.2 0.077 12.0 4.2 1.0 1 0 0 1 1 1 0 CLN3 protein LicD PF04991.13 GBG66928.1 - 0.079 13.1 12.2 0.087 13.0 12.2 1.0 1 0 0 1 1 1 0 LicD family SR-25 PF10500.9 GBG66928.1 - 0.082 12.5 39.0 0.13 11.8 39.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SpoIIP PF07454.11 GBG66928.1 - 0.088 12.2 14.9 0.1 12.0 14.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 GBG66928.1 - 0.095 11.5 15.8 0.11 11.3 15.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MMM1 PF10296.9 GBG66928.1 - 0.14 11.2 4.6 0.13 11.3 4.6 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 PPL5 PF18168.1 GBG66928.1 - 0.14 11.4 15.3 0.16 11.3 15.3 1.0 1 0 0 1 1 1 0 Prim-pol family 5 DDHD PF02862.17 GBG66928.1 - 0.18 11.9 7.3 0.21 11.7 7.3 1.2 1 0 0 1 1 1 0 DDHD domain AP3D1 PF06375.11 GBG66928.1 - 0.19 12.0 43.2 0.047 13.9 17.4 2.1 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 DUF4834 PF16118.5 GBG66928.1 - 0.2 12.6 10.0 0.27 12.2 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PRC2_HTH_1 PF18118.1 GBG66928.1 - 0.21 12.4 16.1 0.29 12.0 16.1 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Ureide_permease PF07168.11 GBG66928.1 - 0.24 10.1 5.0 0.25 10.0 5.0 1.1 1 0 0 1 1 1 0 Ureide permease FGF-BP1 PF06473.12 GBG66928.1 - 0.24 11.2 21.8 0.28 11.0 21.8 1.0 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) NARP1 PF12569.8 GBG66928.1 - 0.27 10.1 25.2 0.29 10.0 25.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPN2_C PF18004.1 GBG66928.1 - 0.28 11.1 29.6 0.35 10.8 29.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SLC12 PF03522.15 GBG66928.1 - 0.28 10.2 13.0 0.3 10.1 13.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 EIIBC-GUT_N PF03612.14 GBG66928.1 - 0.29 10.9 11.0 0.37 10.5 11.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3807 PF12720.7 GBG66928.1 - 0.3 11.4 24.7 0.37 11.0 24.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) O-antigen_lig PF13425.6 GBG66928.1 - 0.3 9.8 6.7 0.3 9.8 6.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Ctr PF04145.15 GBG66928.1 - 0.34 11.5 2.4 0.4 11.3 2.4 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Vfa1 PF08432.10 GBG66928.1 - 0.43 10.9 27.7 0.49 10.7 27.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AIF_C PF14721.6 GBG66928.1 - 0.55 10.6 9.4 0.67 10.3 9.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SID-1_RNA_chan PF13965.6 GBG66928.1 - 0.59 8.5 1.4 0.62 8.4 1.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Cellulose_synt PF03552.14 GBG66928.1 - 0.6 8.5 6.5 0.58 8.6 6.5 1.1 1 0 0 1 1 1 0 Cellulose synthase Med19 PF10278.9 GBG66928.1 - 0.61 10.0 36.5 0.83 9.6 36.5 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Coilin_N PF15862.5 GBG66928.1 - 0.61 9.9 30.2 0.78 9.5 30.2 1.1 1 0 0 1 1 1 0 Coilin N-terminus DUF2126 PF09899.9 GBG66928.1 - 0.65 8.0 5.6 0.68 7.9 5.6 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SRP-alpha_N PF04086.13 GBG66928.1 - 0.66 9.9 23.3 0.76 9.6 23.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RNA_pol_Rpc4 PF05132.14 GBG66928.1 - 0.68 10.3 20.1 0.83 10.1 20.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 GBG66928.1 - 0.78 9.5 20.7 0.85 9.4 20.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4776 PF16003.5 GBG66928.1 - 0.92 8.4 24.0 1.1 8.2 24.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) EOS1 PF12326.8 GBG66928.1 - 1 9.3 8.3 1.2 9.0 8.3 1.2 1 0 0 1 1 1 0 N-glycosylation protein Peroxin-13_N PF04088.13 GBG66928.1 - 1.1 9.6 9.3 1.3 9.3 9.3 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Serinc PF03348.15 GBG66928.1 - 1.1 8.1 4.6 1.1 8.2 4.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) IDO PF01231.18 GBG66928.1 - 1.1 8.0 9.5 1.4 7.6 9.5 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase FAM60A PF15396.6 GBG66928.1 - 1.1 9.2 20.0 1.3 9.0 20.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Folate_carrier PF01770.18 GBG66928.1 - 1.1 7.9 6.8 1.2 7.8 6.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier CCDC106 PF15794.5 GBG66928.1 - 1.2 8.8 22.9 1.6 8.4 22.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 MAP17 PF15807.5 GBG66928.1 - 1.3 9.3 15.5 1.7 8.9 15.5 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Membralin PF09746.9 GBG66928.1 - 1.3 8.0 7.9 1.4 7.9 7.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein Sec62 PF03839.16 GBG66928.1 - 1.3 8.5 20.6 1.7 8.1 20.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF913 PF06025.12 GBG66928.1 - 1.4 7.9 8.3 1.6 7.7 8.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1764 PF08576.10 GBG66928.1 - 1.5 9.8 24.7 2.1 9.3 24.7 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) GAGA_bind PF06217.12 GBG66928.1 - 1.6 8.9 21.8 1.9 8.7 21.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Casc1 PF12366.8 GBG66928.1 - 1.7 8.1 17.2 2.2 7.8 17.2 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 LMBR1 PF04791.16 GBG66928.1 - 1.7 7.4 2.9 1.9 7.3 2.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5308 PF17233.2 GBG66928.1 - 1.8 8.8 6.3 2.1 8.5 6.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) V_ATPase_I PF01496.19 GBG66928.1 - 2 6.2 13.6 2.2 6.1 13.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FHIPEP PF00771.20 GBG66928.1 - 2.2 6.6 4.0 2.7 6.4 4.0 1.3 1 0 0 1 1 1 0 FHIPEP family Asparaginase_2 PF01112.18 GBG66928.1 - 2.4 7.1 6.7 2.6 7.0 6.7 1.1 1 0 0 1 1 1 0 Asparaginase YL1 PF05764.13 GBG66928.1 - 2.5 8.2 28.7 3.1 7.8 28.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Spt20 PF12090.8 GBG66928.1 - 2.5 7.6 20.8 3.1 7.4 20.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF2828 PF11443.8 GBG66928.1 - 2.6 6.0 20.4 3 5.8 20.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3464 PF11947.8 GBG66928.1 - 3.2 7.5 22.2 4.3 7.1 22.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Band_3_cyto PF07565.13 GBG66928.1 - 3.4 7.4 10.9 3.7 7.3 10.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CNDH2_M PF16869.5 GBG66928.1 - 3.5 8.3 10.4 5.2 7.7 10.4 1.2 1 0 0 1 1 1 0 PF16858 RP-C_C PF11800.8 GBG66928.1 - 3.9 7.5 9.8 4.7 7.3 9.8 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_U57 PF05582.12 GBG66928.1 - 4.5 6.4 12.9 5.1 6.3 12.9 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Presenilin PF01080.17 GBG66928.1 - 4.7 5.9 15.0 5.1 5.8 15.0 1.0 1 0 0 1 1 1 0 Presenilin DAG_kinase_N PF14513.6 GBG66928.1 - 4.8 7.4 15.8 5.7 7.1 15.8 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus FAM176 PF14851.6 GBG66928.1 - 5.3 6.7 13.1 1 9.0 8.3 1.8 1 1 1 2 2 2 0 FAM176 family DUF4647 PF15504.6 GBG66928.1 - 5.5 6.0 22.7 6.4 5.8 22.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Hydin_ADK PF17213.3 GBG66928.1 - 5.7 7.2 10.5 6.8 6.9 10.5 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Paramyxo_ncap PF00973.19 GBG66928.1 - 5.9 5.7 13.0 6.4 5.6 13.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SspB PF04386.13 GBG66928.1 - 6.5 6.6 12.3 8.4 6.3 12.3 1.2 1 0 0 1 1 1 0 Stringent starvation protein B EMC3_TMCO1 PF01956.16 GBG66928.1 - 7 6.4 12.8 8.8 6.0 12.8 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Kei1 PF08552.11 GBG66928.1 - 7.1 6.5 6.7 8.2 6.3 6.7 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF755 PF05501.11 GBG66928.1 - 7.3 6.9 36.0 10 6.4 36.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TMEM214 PF10151.9 GBG66928.1 - 8 4.8 24.2 8.9 4.6 24.2 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Zip PF02535.22 GBG66928.1 - 8.1 5.6 14.8 9.4 5.3 14.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4770 PF15994.5 GBG66928.1 - 8.4 6.6 18.6 12 6.1 18.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Neur_chan_memb PF02932.16 GBG66928.1 - 9.5 6.2 11.1 11 6.0 11.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Fe-S_biosyn PF01521.20 GBG66929.1 - 8.8e-23 80.6 0.0 1.1e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis AP2 PF00847.20 GBG66931.1 - 1.6e-06 28.2 0.6 1.6e-06 28.2 0.6 3.2 3 0 0 3 3 3 1 AP2 domain DUF572 PF04502.13 GBG66931.1 - 0.043 13.4 4.4 0.084 12.5 4.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF-3_zeta PF05091.12 GBG66931.1 - 0.59 9.1 10.0 0.99 8.3 10.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pectinesterase PF01095.19 GBG66932.1 - 2e-73 246.7 1.5 3.6e-73 245.9 1.5 1.4 1 1 0 1 1 1 1 Pectinesterase PMEI PF04043.15 GBG66932.1 - 3.3e-05 24.3 6.7 6.2e-05 23.4 6.7 1.5 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor DUF2561 PF10812.8 GBG66932.1 - 0.023 14.7 0.3 0.16 12.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) Retrotrans_gag PF03732.17 GBG66933.1 - 1.1e-05 25.6 0.3 0.26 11.6 0.0 3.1 3 0 0 3 3 3 2 Retrotransposon gag protein DUF1664 PF07889.12 GBG66933.1 - 0.00023 21.2 2.4 0.00038 20.5 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) RVP_2 PF08284.11 GBG66933.1 - 0.00095 18.9 0.0 0.0058 16.4 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease TolA_bind_tri PF16331.5 GBG66933.1 - 0.0082 16.2 3.4 0.0082 16.2 3.4 2.1 1 1 1 2 2 2 1 TolA binding protein trimerisation GAPES4 PF17157.4 GBG66933.1 - 0.011 16.1 0.0 6.8 7.2 0.0 2.8 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain Jnk-SapK_ap_N PF09744.9 GBG66933.1 - 0.014 15.6 5.5 0.024 14.9 5.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 GBG66933.1 - 0.034 13.0 5.9 0.051 12.5 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2730 PF10805.8 GBG66933.1 - 0.037 14.1 0.8 0.084 13.0 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4618 PF15397.6 GBG66933.1 - 0.065 12.6 3.3 0.11 11.9 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Kringle PF00051.18 GBG66933.1 - 0.11 12.8 1.1 20 5.6 0.1 2.9 2 0 0 2 2 2 0 Kringle domain Phage_GPO PF05929.11 GBG66933.1 - 0.23 11.0 1.4 0.44 10.1 1.4 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 GBG66933.1 - 0.27 11.4 3.4 0.47 10.6 3.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TRPM_tetra PF16519.5 GBG66933.1 - 0.32 11.1 2.3 19 5.5 0.2 2.5 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Baculo_PEP_C PF04513.12 GBG66933.1 - 0.38 10.8 4.2 0.61 10.1 4.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 GBG66933.1 - 0.49 10.5 7.2 0.33 11.0 3.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 GBG66933.1 - 0.81 10.2 3.5 0.76 10.3 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 FUSC PF04632.12 GBG66933.1 - 1.3 7.5 3.4 1.8 7.0 3.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Integrase_H2C2 PF17921.1 GBG66934.1 - 2.1e-15 56.6 0.2 3.8e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG66934.1 - 1.5e-06 28.4 0.0 3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG66934.1 - 0.00019 21.6 0.0 0.00038 20.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG66936.1 - 5.6e-05 23.0 1.3 0.00017 21.5 1.3 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG66936.1 - 0.022 14.6 2.9 0.07 13.0 2.9 1.8 1 0 0 1 1 1 0 Zinc knuckle Nop14 PF04147.12 GBG66937.1 - 5.8 5.0 40.2 7.5 4.6 40.2 1.1 1 0 0 1 1 1 0 Nop14-like family FlaC_arch PF05377.11 GBG66938.1 - 0.032 14.6 4.1 0.48 10.8 1.3 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.11 GBG66938.1 - 0.26 10.8 1.1 0.34 10.4 1.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein APH PF01636.23 GBG66938.1 - 1.1 9.1 7.0 1.4 8.8 7.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family TPR_2 PF07719.17 GBG66940.1 - 9e-10 37.9 8.0 0.00012 21.9 1.9 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG66940.1 - 7.7e-08 31.8 8.5 4.7e-05 23.0 1.4 4.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG66940.1 - 3.9e-07 29.8 4.9 0.0011 19.0 0.7 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG66940.1 - 7.5e-07 29.4 8.6 0.00088 19.5 1.2 4.0 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG66940.1 - 6.5e-06 25.8 1.9 0.032 14.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG66940.1 - 6.7e-06 26.7 9.4 0.079 13.6 0.2 4.5 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG66940.1 - 0.00017 22.0 5.1 0.45 11.1 1.3 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 GBG66940.1 - 0.00018 21.9 9.7 0.57 10.9 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG66940.1 - 0.00019 22.0 6.8 0.37 11.7 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG66940.1 - 0.00066 19.5 6.8 0.005 16.7 1.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GBG66940.1 - 0.0037 17.4 0.4 1.8 8.7 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG66940.1 - 0.0056 17.0 3.7 11 6.6 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GBG66940.1 - 0.01 15.9 0.2 1 9.5 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 GBG66940.1 - 0.028 14.1 1.5 2.2 8.0 0.9 3.2 3 0 0 3 3 3 0 TPR repeat ANAPC5 PF12862.7 GBG66940.1 - 0.084 13.0 0.6 4.7 7.4 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 NARP1 PF12569.8 GBG66940.1 - 0.1 11.5 0.6 0.42 9.5 0.1 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF659 PF04937.15 GBG66941.1 - 2.8e-40 137.6 0.0 5.7e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG66941.1 - 0.00029 20.6 0.0 0.00029 20.6 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IL5 PF02025.15 GBG66941.1 - 0.16 12.3 0.0 0.63 10.4 0.0 1.9 2 0 0 2 2 2 0 Interleukin 5 PPP4R2 PF09184.11 GBG66941.1 - 6.3 6.3 21.7 15 5.1 21.7 1.6 1 0 0 1 1 1 0 PPP4R2 TPR_1 PF00515.28 GBG66942.1 - 6.5e-34 114.4 4.8 2.4e-05 24.0 0.0 8.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 GBG66942.1 - 1.4e-32 109.2 0.2 3e-05 23.8 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 GBG66942.1 - 2.3e-26 89.8 2.6 0.0027 17.8 0.6 8.4 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 GBG66942.1 - 5.2e-24 83.6 1.0 0.011 15.4 0.0 8.2 6 2 2 8 8 8 6 TPR repeat TPR_12 PF13424.6 GBG66942.1 - 1.5e-23 82.9 0.0 2e-06 28.0 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GBG66942.1 - 5.2e-23 81.4 0.0 1.2e-05 25.9 0.0 4.9 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 GBG66942.1 - 1e-19 69.5 0.0 0.018 15.8 0.0 6.8 4 2 3 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 GBG66942.1 - 7.8e-18 63.5 0.2 0.035 14.5 0.0 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 GBG66942.1 - 2.5e-17 63.2 0.0 0.0005 20.5 0.0 5.3 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 GBG66942.1 - 3.8e-15 54.7 0.1 0.00014 21.6 0.1 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG66942.1 - 1.3e-14 53.7 2.7 0.0012 19.4 0.0 6.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 GBG66942.1 - 5.4e-08 32.9 0.0 0.016 15.4 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG66942.1 - 1.5e-06 28.3 2.0 0.13 12.5 0.0 4.4 3 2 2 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 GBG66942.1 - 1.2e-05 24.9 0.0 0.0079 15.6 0.0 3.2 2 1 1 3 3 3 1 MalT-like TPR region Fis1_TPR_C PF14853.6 GBG66942.1 - 2.3e-05 24.4 0.9 0.72 10.0 0.0 4.0 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.9 GBG66942.1 - 0.0011 18.7 1.2 3.8 7.2 0.4 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 GBG66942.1 - 0.002 17.9 11.5 3.7 7.6 0.1 7.2 7 1 0 7 7 7 1 Tetratricopeptide repeat PknG_TPR PF16918.5 GBG66942.1 - 0.0049 15.6 0.0 0.32 9.7 0.0 2.6 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_4 PF07721.14 GBG66942.1 - 0.0049 17.4 0.0 66 4.6 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat NARP1 PF12569.8 GBG66942.1 - 0.005 15.8 2.2 0.77 8.6 0.3 3.6 1 1 2 4 4 4 1 NMDA receptor-regulated protein 1 DUF5112 PF17139.4 GBG66942.1 - 0.01 15.3 1.7 0.39 10.2 2.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5112) TPR_20 PF14561.6 GBG66942.1 - 0.012 15.9 2.9 3.5 8.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GBG66942.1 - 0.033 13.6 0.2 1.5 8.2 0.0 2.9 2 2 1 3 3 3 0 Coatomer epsilon subunit TPR_3 PF07720.12 GBG66942.1 - 0.033 14.2 12.0 0.084 12.9 0.9 4.3 6 0 0 6 6 3 0 Tetratricopeptide repeat TOM20_plant PF06552.12 GBG66942.1 - 0.097 12.4 1.3 32 4.2 0.1 3.9 3 1 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Alkyl_sulf_dimr PF14863.6 GBG66942.1 - 0.098 13.1 0.4 8 6.9 0.0 3.2 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation BRO1 PF03097.18 GBG66942.1 - 0.14 11.0 1.5 2.3 6.9 0.1 2.2 2 0 0 2 2 2 0 BRO1-like domain MIT PF04212.18 GBG66942.1 - 2.7 8.1 9.1 13 6.0 0.4 4.5 6 0 0 6 6 4 0 MIT (microtubule interacting and transport) domain PSII PF00421.19 GBG66943.1 - 4.4e-34 118.0 0.0 4.7e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Photosystem II protein TAF PF02969.17 GBG66944.1 - 4.9e-25 87.5 0.1 8.6e-25 86.7 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Mito_carr PF00153.27 GBG66946.1 - 1.1e-37 127.8 0.1 2.1e-13 50.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GBG66946.1 - 4.3e-11 43.1 0.3 0.00011 22.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG66946.1 - 6.5e-06 25.3 0.0 0.16 11.6 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GBG66946.1 - 1.6e-05 24.5 0.0 0.54 10.3 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GBG66946.1 - 0.0021 17.9 0.1 1.9 8.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 GBG66947.1 - 2.1e-11 44.1 0.2 7.3e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG66947.1 - 2.6e-06 26.6 0.0 0.11 12.1 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GBG66947.1 - 7e-06 25.6 0.0 0.39 10.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain Mito_carr PF00153.27 GBG66947.1 - 1.4e-05 24.9 0.0 4.1e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial carrier protein EF-hand_8 PF13833.6 GBG66947.1 - 0.001 18.8 0.1 1.3 8.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair Mito_carr PF00153.27 GBG66948.1 - 9.3e-41 137.7 0.1 2.7e-15 56.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GBG66948.1 - 7.2e-07 29.6 0.2 0.013 15.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG66948.1 - 0.006 16.4 0.0 3.4 7.8 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GBG66948.1 - 0.081 12.8 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair RT_RNaseH_2 PF17919.1 GBG66950.1 - 2.9e-27 94.6 0.0 4.8e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG66950.1 - 1.7e-24 86.1 0.0 3.1e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG66950.1 - 4.4e-09 36.2 0.1 6.7e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ferritin PF00210.24 GBG66951.1 - 1.2e-18 67.4 0.2 1.4e-18 67.2 0.2 1.1 1 0 0 1 1 1 1 Ferritin-like domain DUF3506 PF12014.8 GBG66952.1 - 1.9e-26 92.8 0.0 8.2e-26 90.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) UVR PF02151.19 GBG66952.1 - 5.7e-06 25.9 8.6 0.00094 18.9 1.1 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif DUF5089 PF17002.5 GBG66952.1 - 0.059 13.2 0.4 0.14 12.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) NPCBM_assoc PF10633.9 GBG66952.1 - 0.072 13.4 0.1 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase WD40 PF00400.32 GBG66953.1 - 2.5e-48 161.0 29.9 3.9e-08 33.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG66953.1 - 7e-11 42.3 1.2 0.056 13.7 0.0 5.0 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG66953.1 - 0.00023 21.1 0.5 0.042 13.7 0.0 3.0 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GBG66953.1 - 0.00068 18.7 0.1 4 6.3 0.0 4.0 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GBG66953.1 - 0.002 16.9 9.2 0.83 8.2 0.0 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 GBG66953.1 - 0.0022 16.6 0.1 0.091 11.3 0.2 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 GBG66953.1 - 0.055 13.4 1.0 42 4.2 0.1 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 GBG66953.1 - 0.07 12.4 0.0 5.9 6.1 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain DUF1416 PF07210.12 GBG66953.1 - 0.082 12.8 0.3 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) TRAPPC9-Trs120 PF08626.11 GBG66954.1 - 0.0074 13.7 0.0 0.011 13.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit RVT_1 PF00078.27 GBG66955.1 - 2.8e-11 43.4 0.0 5.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG66955.1 - 3.4e-11 43.4 0.0 1.7e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG66955.1 - 2.8e-07 31.1 0.0 1.4e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG66955.1 - 7.7e-07 29.6 0.0 2.2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG66955.1 - 1.8e-06 28.1 0.0 0.0054 17.0 0.0 3.0 2 0 0 2 2 2 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG66955.1 - 0.00033 20.4 0.0 0.0041 16.9 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG66955.1 - 0.00056 19.7 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG66956.1 - 1e-24 87.3 0.1 1.5e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG66956.1 - 0.0088 16.1 0.0 0.039 14.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4399 PF14347.6 GBG66956.1 - 0.14 12.6 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) HTH_Tnp_Tc5 PF03221.16 GBG66957.1 - 1.9e-12 47.0 1.7 3.3e-12 46.3 0.4 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 GBG66957.1 - 3.4e-12 46.3 0.1 7.6e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 GBG66957.1 - 6.5e-06 26.4 0.1 2e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 Transposase BrkDBD PF09607.10 GBG66957.1 - 0.001 18.8 0.3 0.0045 16.7 0.0 2.2 2 0 0 2 2 2 1 Brinker DNA-binding domain CENP-B_N PF04218.13 GBG66957.1 - 0.0019 17.8 0.1 0.004 16.8 0.1 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 GBG66957.1 - 0.0093 15.7 0.0 0.032 14.0 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 GBG66957.1 - 0.025 14.0 0.2 6 6.4 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 RVT_1 PF00078.27 GBG66958.1 - 9.2e-08 31.9 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAS4 PF15460.6 GBG66958.1 - 6.6 6.9 7.0 2.9 8.0 1.7 2.8 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 Chromo PF00385.24 GBG66960.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3270 PF11674.8 GBG66963.1 - 2.9 8.1 4.3 2.6 8.3 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) EcsC PF12787.7 GBG66965.1 - 0.054 13.2 5.0 0.072 12.8 5.0 1.1 1 0 0 1 1 1 0 EcsC protein family DUF948 PF06103.11 GBG66965.1 - 0.12 12.6 3.9 0.13 12.5 2.2 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-Q PF13094.6 GBG66965.1 - 0.36 11.0 5.0 0.6 10.3 5.0 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Mre11_DNA_bind PF04152.14 GBG66965.1 - 3 8.2 9.3 5.2 7.4 1.5 2.1 1 1 1 2 2 2 0 Mre11 DNA-binding presumed domain DUF1690 PF07956.11 GBG66965.1 - 3.8 7.9 7.7 21 5.5 7.7 1.9 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) FlaG PF03646.15 GBG66965.1 - 6.6 7.0 10.6 4.4 7.5 3.2 2.3 1 1 1 2 2 2 0 FlaG protein NACHT_N PF17100.5 GBG66965.1 - 7.7 6.3 9.2 3.2 7.6 3.0 2.0 1 1 1 2 2 2 0 N-terminal domain of NWD NACHT-NTPase Phage_lysozyme PF00959.19 GBG66966.1 - 0.091 13.2 0.4 0.65 10.5 0.0 2.6 3 0 0 3 3 3 0 Phage lysozyme Myb_DNA-bind_4 PF13837.6 GBG66968.1 - 5.7e-08 33.0 4.2 2.4e-07 31.0 4.2 2.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG66968.1 - 0.11 12.9 2.6 0.17 12.2 1.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG66968.1 - 0.12 12.5 1.2 0.25 11.4 1.2 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG66968.1 - 1 9.6 7.8 0.087 13.0 1.2 2.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG66970.1 - 2e-07 30.8 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_28 PF03033.20 GBG66971.1 - 2.9e-32 111.6 0.0 5.2e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 GBG66971.1 - 2e-29 102.7 0.1 6.2e-22 78.3 0.0 3.3 2 1 1 3 3 3 3 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.6 GBG66971.1 - 0.00013 22.4 2.2 0.00019 21.9 0.9 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GBG66971.1 - 0.0021 18.1 0.2 0.009 16.0 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_transf_28 PF03033.20 GBG66972.1 - 2.8e-32 111.7 0.0 5e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 GBG66972.1 - 1.3e-30 106.6 0.0 1.5e-25 90.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.6 GBG66972.1 - 0.00016 22.2 2.5 0.00018 22.0 0.9 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GBG66972.1 - 0.002 18.1 0.2 0.0087 16.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 UDPGT PF00201.18 GBG66972.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Ribosomal_L27 PF01016.19 GBG66973.1 - 4.6e-36 122.7 1.1 7.2e-36 122.1 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein SPRY PF00622.28 GBG66973.1 - 0.08 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 SPRY domain Vps26 PF03643.15 GBG66974.1 - 1.7e-12 47.0 1.2 7.3e-08 31.7 0.2 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 DDE_Tnp_4 PF13359.6 GBG66976.1 - 1.1e-29 103.2 0.0 1.9e-28 99.1 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66976.1 - 2.5e-15 56.7 0.0 3.7e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG66976.1 - 1.8e-05 24.5 0.3 0.00015 21.5 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG66977.1 - 3.1e-06 27.5 3.8 7.6e-06 26.2 3.8 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain LapA_dom PF06305.11 GBG66977.1 - 0.068 13.0 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Aminoglyc_resit PF10706.9 GBG66980.1 - 0.0092 15.7 0.0 0.06 13.1 0.1 2.1 2 0 0 2 2 2 1 Aminoglycoside-2''-adenylyltransferase zf-CCHC PF00098.23 GBG66982.1 - 7.5e-06 25.8 3.8 1.3e-05 25.1 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG66982.1 - 0.55 10.1 3.9 0.82 9.6 3.9 1.3 1 0 0 1 1 1 0 Zinc knuckle V_ATPase_I PF01496.19 GBG66982.1 - 2.9 5.7 7.4 3.8 5.3 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Membralin PF09746.9 GBG66982.1 - 3.4 6.6 5.0 5.4 6.0 5.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF659 PF04937.15 GBG66983.1 - 2.6e-13 50.1 0.0 4.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4889 PF16230.5 GBG66983.1 - 5.3 7.3 8.9 16 5.8 0.0 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4889) Importin_rep_4 PF18808.1 GBG66984.1 - 2.9e-23 81.9 9.6 7.4e-23 80.7 0.1 4.8 4 0 0 4 4 4 1 Importin repeat HEAT PF02985.22 GBG66984.1 - 1.4e-21 74.7 18.7 0.0014 18.7 0.0 11.1 12 0 0 12 12 10 4 HEAT repeat HEAT_2 PF13646.6 GBG66984.1 - 2e-16 60.1 17.1 4.1e-10 39.9 0.6 8.6 4 3 6 10 10 10 3 HEAT repeats Vac14_Fab1_bd PF12755.7 GBG66984.1 - 1.6e-13 51.0 2.4 0.0012 19.4 0.0 7.1 5 1 3 8 8 6 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 GBG66984.1 - 1.7e-12 47.6 30.7 0.00094 19.6 0.1 12.3 11 2 3 14 14 13 3 HEAT-like repeat Cnd1 PF12717.7 GBG66984.1 - 1.6e-07 31.5 11.9 0.0016 18.5 0.0 6.3 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GBG66984.1 - 2.4e-06 27.4 2.6 1.1 9.4 0.0 6.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 GBG66984.1 - 4e-06 26.2 4.7 0.062 12.4 0.1 5.0 3 2 1 5 5 5 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 GBG66984.1 - 0.00027 20.8 4.5 0.0053 16.6 0.4 4.6 5 0 0 5 5 5 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GBG66984.1 - 0.0005 20.2 3.1 4.9 7.2 0.0 4.9 3 2 1 4 4 4 1 Exportin 1-like protein DUF3385 PF11865.8 GBG66984.1 - 0.0023 17.9 1.7 9 6.2 0.0 5.8 4 2 2 7 7 7 1 Domain of unknown function (DUF3385) HEAT_PBS PF03130.16 GBG66984.1 - 0.0024 18.4 7.9 0.3 11.9 0.0 6.9 7 1 0 7 7 6 1 PBS lyase HEAT-like repeat DUF4042 PF13251.6 GBG66984.1 - 0.0035 17.1 1.9 0.88 9.3 0.0 4.5 3 2 1 4 4 4 1 Domain of unknown function (DUF4042) Importin_rep_6 PF18829.1 GBG66984.1 - 0.0043 17.2 0.2 0.0043 17.2 0.2 2.5 2 0 0 2 2 1 1 Importin repeat 6 Nipped-B_C PF12830.7 GBG66984.1 - 0.2 11.6 1.3 63 3.4 0.0 4.0 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus Asp1 PF16993.5 GBG66984.1 - 1.3 8.2 4.4 2 7.5 4.4 1.2 1 0 0 1 1 1 0 Accessory Sec system protein Asp1 BSP_II PF05432.11 GBG66984.1 - 2.6 7.6 8.8 2.4 7.8 5.0 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Cnd3 PF12719.7 GBG66984.1 - 3.4 6.8 18.2 0.68 9.1 2.9 6.0 6 2 1 7 7 7 0 Nuclear condensing complex subunits, C-term domain FKBP_N PF01346.18 GBG66984.1 - 6.2 7.8 9.1 2.1 9.3 4.8 2.5 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Myb_DNA-bind_4 PF13837.6 GBG66985.1 - 1.8e-06 28.3 1.9 3.1e-06 27.5 0.4 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Chromo PF00385.24 GBG66991.1 - 2.2e-12 46.7 0.0 4.2e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG66991.1 - 1.8e-11 44.3 0.0 5.1e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain TcdA_TcdB PF12919.7 GBG66994.1 - 0.17 11.1 0.2 0.84 8.9 0.0 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DDE_Tnp_4 PF13359.6 GBG66995.1 - 4.7e-25 88.1 0.0 8.9e-25 87.2 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG66995.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Sld5 PF05916.11 GBG66996.1 - 0.85 10.1 3.2 9.4 6.8 1.1 2.8 1 1 1 2 2 2 0 GINS complex protein Mucin PF01456.17 GBG66997.1 - 0.21 11.6 34.5 0.045 13.8 26.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-CCHC PF00098.23 GBG66999.1 - 0.044 13.9 1.9 0.073 13.2 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2935 PF11155.8 GBG67000.1 - 0.12 12.7 0.4 4.9 7.5 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) ATG16 PF08614.11 GBG67000.1 - 1.4 9.1 15.0 0.93 9.7 6.9 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 GBG67000.1 - 2.1 8.8 5.5 0.76 10.2 1.3 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) GPS2_interact PF15784.5 GBG67000.1 - 3.7 8.1 12.1 1.3 9.5 2.1 3.5 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain DUF2968 PF11180.8 GBG67000.1 - 6.6 6.3 13.8 3.5 7.2 9.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Com_YlbF PF06133.11 GBG67000.1 - 7.4 7.2 12.7 0.61 10.7 4.9 2.6 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA LZ_Tnp_IS66 PF13007.7 GBG67001.1 - 0.031 15.1 4.0 0.053 14.3 4.0 1.3 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain CENP-Q PF13094.6 GBG67001.1 - 0.32 11.2 6.6 0.57 10.4 6.6 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF5091 PF17012.5 GBG67002.1 - 0.1 12.9 0.8 0.23 11.7 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5091) OAD_gamma PF04277.13 GBG67002.1 - 0.68 10.6 4.2 0.52 10.9 1.6 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain BUD22 PF09073.10 GBG67003.1 - 0.0052 16.2 14.2 0.0052 16.2 14.2 2.8 1 1 2 3 3 3 1 BUD22 SAPS PF04499.15 GBG67003.1 - 0.96 8.2 0.0 0.96 8.2 0.0 2.0 1 1 1 2 2 2 0 SIT4 phosphatase-associated protein Orf78 PF06024.12 GBG67003.1 - 2.9 8.2 0.0 2.9 8.2 0.0 3.9 2 1 0 2 2 2 0 Orf78 (ac78) RPA43_OB PF17875.1 GBG67004.1 - 4e-08 33.9 12.3 7.9e-07 29.7 0.0 4.3 3 2 1 4 4 4 3 RPA43 OB domain in RNA Pol I SR-25 PF10500.9 GBG67004.1 - 0.0026 17.4 3.7 0.0026 17.4 3.7 2.7 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4770 PF15994.5 GBG67004.1 - 0.02 15.1 1.5 0.02 15.1 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) RPA43_OB PF17875.1 GBG67005.1 - 5.6e-08 33.5 12.9 7.6e-07 29.8 0.0 4.3 3 2 1 4 4 4 2 RPA43 OB domain in RNA Pol I SR-25 PF10500.9 GBG67005.1 - 0.0061 16.2 4.9 0.0061 16.2 4.9 2.7 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4770 PF15994.5 GBG67005.1 - 0.02 15.1 1.0 0.02 15.1 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) AIM3 PF17096.5 GBG67005.1 - 0.044 14.7 3.2 0.044 14.7 3.2 2.8 2 1 1 3 3 3 0 Altered inheritance of mitochondria protein 3 RNA_pol_Rbc25 PF08292.12 GBG67005.1 - 0.87 9.8 7.6 0.064 13.5 1.2 2.4 2 1 0 2 2 2 0 RNA polymerase III subunit Rpc25 CDC45 PF02724.14 GBG67005.1 - 9.1 4.4 10.3 0.43 8.8 0.3 2.1 2 0 0 2 2 2 0 CDC45-like protein AAA PF00004.29 GBG67006.1 - 8.7e-41 139.4 0.0 2.5e-40 138.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG67006.1 - 1.9e-10 40.4 0.1 3.5e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GBG67006.1 - 9.8e-09 35.1 0.1 2.7e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 GBG67006.1 - 7.8e-06 26.2 0.7 0.011 16.0 0.1 2.7 2 1 1 3 3 3 2 AAA domain DUF815 PF05673.13 GBG67006.1 - 7.3e-05 22.0 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 GBG67006.1 - 7.5e-05 22.9 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GBG67006.1 - 0.00018 21.5 0.1 0.00086 19.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG67006.1 - 0.00022 21.7 0.2 0.0016 18.8 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GBG67006.1 - 0.0014 18.3 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 GBG67006.1 - 0.0064 15.9 0.1 0.24 10.7 0.1 2.3 1 1 0 2 2 2 1 KaiC AAA_3 PF07726.11 GBG67006.1 - 0.017 15.0 0.1 0.069 13.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 GBG67006.1 - 0.019 14.2 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 GBG67006.1 - 0.021 15.2 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 GBG67006.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 GBG67006.1 - 0.044 14.3 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GBG67006.1 - 0.064 13.0 0.1 0.18 11.5 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 GBG67006.1 - 0.065 12.9 0.7 0.14 11.8 0.2 1.9 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 GBG67006.1 - 0.08 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GBG67006.1 - 0.09 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GBG67006.1 - 0.095 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 GBG67006.1 - 0.11 12.4 0.2 0.29 11.0 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 GBG67006.1 - 0.13 11.7 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 GBG67006.1 - 0.14 12.4 0.3 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG67006.1 - 0.2 11.2 0.6 0.95 9.0 0.2 2.1 1 1 1 2 2 2 0 AAA domain ubiquitin PF00240.23 GBG67007.1 - 1.4e-34 117.7 0.4 1.8e-34 117.3 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 GBG67007.1 - 1.7e-31 107.8 10.2 2.6e-31 107.2 10.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 GBG67007.1 - 1.6e-16 59.8 0.6 1.6e-16 59.8 0.6 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GBG67007.1 - 2.8e-05 24.5 0.1 0.00011 22.5 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GBG67007.1 - 0.0051 16.7 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GBG67007.1 - 0.0066 16.5 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GBG67007.1 - 0.0068 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain zf-C4pol PF14260.6 GBG67007.1 - 0.0074 16.7 0.8 0.013 16.0 0.8 1.3 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Ubiquitin_4 PF18036.1 GBG67007.1 - 0.019 15.0 1.0 4 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 GBG67007.1 - 0.022 15.3 0.1 0.025 15.1 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ABC_tran PF00005.27 GBG67008.1 - 5.8e-33 114.3 0.0 8.6e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG67008.1 - 3.6e-11 43.4 0.0 2.7e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GBG67008.1 - 1.1e-08 34.8 0.0 0.00036 20.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GBG67008.1 - 5.8e-05 23.7 0.1 8.3e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GBG67008.1 - 9.5e-05 22.1 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 GBG67008.1 - 0.0035 17.1 0.0 0.0092 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 GBG67008.1 - 0.0045 15.9 0.0 2 7.1 0.0 2.9 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 GBG67008.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 GBG67008.1 - 0.0072 16.7 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GBG67008.1 - 0.01 16.3 0.0 0.067 13.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG67008.1 - 0.031 14.6 0.0 0.25 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG67008.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 GBG67008.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 GBG67008.1 - 0.084 13.1 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 GBG67008.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit SbcCD_C PF13558.6 GBG67008.1 - 0.12 12.6 0.1 1.2 9.4 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 GBG67008.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 GBG67008.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 GBG67009.1 - 6.2e-33 114.2 0.0 9.2e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG67009.1 - 3.9e-11 43.3 0.0 2.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GBG67009.1 - 1.2e-08 34.6 0.0 0.00038 20.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GBG67009.1 - 6e-05 23.6 0.1 8.6e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GBG67009.1 - 0.0001 22.0 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 GBG67009.1 - 0.0037 17.0 0.0 0.01 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 GBG67009.1 - 0.005 15.7 0.0 2.1 7.0 0.0 2.9 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 GBG67009.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 GBG67009.1 - 0.0074 16.7 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GBG67009.1 - 0.011 16.2 0.0 0.071 13.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG67009.1 - 0.034 14.4 0.0 0.27 11.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG67009.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 GBG67009.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 GBG67009.1 - 0.091 13.0 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 GBG67009.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit SbcCD_C PF13558.6 GBG67009.1 - 0.13 12.5 0.1 1.2 9.4 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 GBG67009.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 GBG67009.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain XPG_N PF00752.17 GBG67011.1 - 5.9e-29 100.5 0.0 1.2e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 GBG67011.1 - 4.4e-24 84.6 0.0 1.2e-23 83.3 0.0 1.8 1 0 0 1 1 1 1 XPG I-region UBM PF14377.6 GBG67011.1 - 0.00051 19.4 1.3 0.00051 19.4 1.3 2.3 2 0 0 2 2 2 1 Ubiquitin binding region Exo_endo_phos PF03372.23 GBG67012.1 - 0.00082 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG67012.1 - 0.087 12.7 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GBG67013.1 - 1e-12 48.1 0.2 1.8e-12 47.3 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG67013.1 - 9.4e-06 25.5 0.0 0.00033 20.5 0.0 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Thioredoxin PF00085.20 GBG67014.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 GBG67014.1 - 0.0007 19.3 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin CLP_protease PF00574.23 GBG67015.1 - 1e-53 182.0 0.0 1.6e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Clp protease MYT1 PF08474.11 GBG67015.1 - 0.42 10.5 5.1 1.2 9.0 5.1 1.7 1 0 0 1 1 1 0 Myelin transcription factor 1 PH PF00169.29 GBG67016.1 - 8.8e-15 55.1 0.0 4.5e-14 52.8 0.0 2.2 1 1 0 1 1 1 1 PH domain TMF_DNA_bd PF12329.8 GBG67016.1 - 0.25 11.4 5.2 1.4 8.9 5.2 2.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SPATA1_C PF15743.5 GBG67016.1 - 0.52 10.4 8.1 3.7 7.6 5.6 3.1 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus GSHPx PF00255.19 GBG67017.1 - 8e-32 109.0 0.0 1.2e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 GBG67017.1 - 1e-06 28.7 0.8 1.6e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 GBG67017.1 - 0.0021 17.8 0.0 0.0052 16.5 0.0 1.6 2 0 0 2 2 2 1 Redoxin Bd3614-deam PF14439.6 GBG67017.1 - 0.13 12.4 3.2 2 8.5 5.4 1.8 2 0 0 2 2 2 0 Bd3614-like deaminase Histone PF00125.24 GBG67018.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Pkinase_Tyr PF07714.17 GBG67021.1 - 5.5e-37 127.4 0.0 1.1e-36 126.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG67021.1 - 8.7e-36 123.6 0.0 1.3e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG67021.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG67021.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF5021 PF16424.5 GBG67023.1 - 0.0032 17.3 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5021) Peptidase_C48 PF02902.19 GBG67024.1 - 2.2e-16 60.3 0.0 4.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SlyX PF04102.12 GBG67024.1 - 0.19 12.4 1.1 0.85 10.3 1.1 2.1 1 0 0 1 1 1 0 SlyX Pkinase_Tyr PF07714.17 GBG67025.1 - 2.4e-36 125.4 0.0 4.7e-36 124.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG67025.1 - 2.7e-36 125.3 0.0 3.9e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG67025.1 - 0.013 15.5 0.0 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG67025.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RT_RNaseH_2 PF17919.1 GBG67026.1 - 1.2e-25 89.5 0.0 2.2e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67026.1 - 5.8e-25 87.6 0.0 9.8e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67026.1 - 1e-17 64.4 0.1 1.4e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG67027.1 - 3.1e-37 128.3 0.0 6.7e-37 127.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG67027.1 - 5.7e-36 124.2 0.0 8.8e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG67027.1 - 0.025 13.3 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GBG67027.1 - 0.045 13.7 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RVT_1 PF00078.27 GBG67028.1 - 0.18 11.3 0.0 0.6 9.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG67029.1 - 4.6e-12 46.1 0.0 3.6e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG67030.1 - 2.8e-28 99.0 0.1 4.5e-28 98.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67030.1 - 1.9e-17 63.1 0.2 5.4e-17 61.6 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG67030.1 - 2.3e-15 56.8 0.0 4.7e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67030.1 - 1.9e-09 37.5 0.0 6e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG67030.1 - 0.05 13.8 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF5568 PF17724.1 GBG67031.1 - 0.0058 16.5 4.0 0.0058 16.5 4.0 2.4 1 1 1 2 2 2 2 Family of unknown function (DUF5568) Pkinase_Tyr PF07714.17 GBG67032.1 - 4.5e-38 131.0 0.0 7.8e-38 130.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG67032.1 - 2.4e-36 125.5 0.0 3.3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG67032.1 - 0.03 13.1 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GBG67032.1 - 0.049 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 GBG67033.1 - 1.1e-24 86.4 0.0 2.4e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67033.1 - 1.2e-23 83.4 0.0 2.8e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67033.1 - 2.1e-23 83.0 0.0 5e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM76 PF16046.5 GBG67033.1 - 0.031 13.6 3.2 0.07 12.5 3.2 1.5 1 0 0 1 1 1 0 FAM76 protein DUF4666 PF15697.5 GBG67033.1 - 2.2 9.0 4.6 1.9 9.2 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) eIF3_subunit PF08597.10 GBG67033.1 - 10 6.0 13.0 18 5.2 13.0 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pkinase_Tyr PF07714.17 GBG67034.1 - 1.1e-37 129.7 0.0 2.8e-37 128.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG67034.1 - 4.5e-36 124.6 0.0 6.3e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG67034.1 - 0.025 13.4 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GBG67034.1 - 0.042 13.8 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 GBG67035.1 - 9.3e-37 126.8 0.0 1.3e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG67035.1 - 9.7e-37 126.6 0.0 1.7e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG67035.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 GBG67036.1 - 2e-23 82.3 0.0 3.5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67036.1 - 3e-20 72.4 0.0 5.5e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67036.1 - 3.7e-06 26.6 0.0 6.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG67036.1 - 0.2 11.0 8.5 0.29 10.5 8.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG67036.1 - 2.3 6.4 6.6 3.1 6.0 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG67036.1 - 2.3 6.3 11.1 3 6.0 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF659 PF04937.15 GBG67037.1 - 8.1e-21 74.5 0.3 1.3e-20 73.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG67037.1 - 2.6e-06 27.1 0.9 6.1e-06 25.9 0.9 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Kinesin PF00225.23 GBG67038.1 - 2.6e-84 283.0 0.0 5.6e-84 281.9 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG67038.1 - 5.5e-41 140.0 0.0 1.6e-40 138.5 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding DUF1180 PF06679.12 GBG67040.1 - 6.9 7.1 6.9 21 5.5 6.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2076 PF09849.9 GBG67040.1 - 7.8 6.5 18.3 63 3.5 18.2 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MULE PF10551.9 GBG67041.1 - 2.1e-17 63.3 0.0 5.5e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG67041.1 - 3.6e-11 42.9 0.0 1.2e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 MuDR family transposase Transposase_mut PF00872.18 GBG67041.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family SOG2 PF10428.9 GBG67041.1 - 1.1 8.4 25.4 2.1 7.5 25.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein MSA-2c PF12238.8 GBG67042.1 - 4.2 7.3 8.8 6.6 6.7 8.8 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Myb_DNA-bind_4 PF13837.6 GBG67043.1 - 1.1e-10 41.7 3.1 8.9e-10 38.8 0.6 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67043.1 - 0.04 14.2 0.4 0.1 12.9 0.4 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG67044.1 - 3.4e-29 101.5 0.0 1.3e-28 99.6 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67044.1 - 1.5e-16 60.6 0.0 3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67044.1 - 3e-07 30.3 0.1 0.023 14.3 0.0 3.6 4 0 0 4 4 4 3 Transposase DDE domain Phage_holin_3_5 PF16085.5 GBG67046.1 - 6 7.0 11.9 0.036 14.2 2.8 1.9 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III zf-CCHC_4 PF14392.6 GBG67047.1 - 0.034 13.9 0.8 0.078 12.7 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-nanos PF05741.13 GBG67047.1 - 0.19 12.0 2.2 0.26 11.5 0.5 2.1 2 0 0 2 2 2 0 Nanos RNA binding domain zf-CCHC PF00098.23 GBG67050.1 - 2e-08 33.9 1.2 2e-08 33.9 1.2 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG67050.1 - 0.022 14.6 2.7 0.022 14.6 2.7 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG67050.1 - 0.12 12.2 0.9 0.63 9.8 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG67050.1 - 0.32 11.0 3.1 1.5 8.8 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG67051.1 - 0.00027 21.4 0.0 0.00087 19.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67051.1 - 0.019 15.6 0.1 0.059 14.0 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease Asp_protease PF09668.10 GBG67051.1 - 0.022 14.6 0.1 0.082 12.7 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG67051.1 - 0.027 14.7 0.2 0.13 12.6 0.1 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 GBG67051.1 - 0.055 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1664 PF07889.12 GBG67051.1 - 0.17 11.9 0.5 2.9 8.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-CCHC_2 PF13696.6 GBG67051.1 - 0.26 11.2 0.5 0.39 10.6 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG67053.1 - 4.4e-06 27.2 0.1 1.6e-05 25.3 0.0 2.0 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67053.1 - 0.0004 21.0 0.1 0.001 19.7 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG67053.1 - 0.0023 17.7 0.1 0.0037 17.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG67053.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG67054.1 - 5.8e-19 67.9 1.2 1.5e-18 66.7 1.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG67054.1 - 3.2e-17 62.7 0.0 8.4e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67054.1 - 1.7e-16 60.1 0.0 3.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67054.1 - 6.1e-14 52.2 0.0 1.6e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG67054.1 - 1.3e-06 28.9 0.1 3.8e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67054.1 - 9.8e-05 22.9 0.1 0.00029 21.4 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG67054.1 - 0.00071 19.4 0.1 0.0015 18.4 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG67054.1 - 0.01 16.1 0.2 0.022 14.9 0.2 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 GBG67054.1 - 0.079 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease MFMR_assoc PF16596.5 GBG67054.1 - 0.08 13.4 2.8 0.19 12.2 2.8 1.6 1 0 0 1 1 1 0 Disordered region downstream of MFMR Pkinase_Tyr PF07714.17 GBG67055.1 - 2e-37 128.9 0.0 4.7e-37 127.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG67055.1 - 5.4e-37 127.6 0.0 8.2e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Integrase_H2C2 PF17921.1 GBG67055.1 - 4.4e-18 65.1 0.3 1.1e-17 63.8 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG67055.1 - 1e-10 41.8 0.1 3e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG67055.1 - 2.5e-07 31.2 0.0 7.5e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67055.1 - 2e-05 25.0 0.0 5.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67055.1 - 7.7e-05 22.5 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG67055.1 - 0.00031 20.3 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG67055.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG67055.1 - 0.0035 17.4 0.0 0.012 15.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase_fungal PF17667.1 GBG67055.1 - 0.12 11.2 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APG17 PF04108.12 GBG67055.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Senescence_reg PF04520.13 GBG67055.1 - 8.5 7.2 9.3 0.22 12.4 1.3 2.2 2 0 0 2 2 2 0 Senescence regulator MULE PF10551.9 GBG67057.1 - 4.8e-12 46.1 0.0 1.4e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG67057.1 - 2e-10 40.5 0.1 2e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 MuDR family transposase zinc_ribbon_4 PF13717.6 GBG67059.1 - 0.13 12.2 0.3 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain EPF PF17181.4 GBG67060.1 - 0.012 15.6 1.9 0.056 13.5 1.9 2.2 1 0 0 1 1 1 0 Epidermal patterning factor proteins DUF1180 PF06679.12 GBG67061.1 - 0.17 12.3 8.2 0.39 11.1 8.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2457 PF10446.9 GBG67062.1 - 0.0048 16.1 25.1 0.0056 15.9 25.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.12 GBG67062.1 - 0.12 10.6 13.4 0.13 10.5 13.4 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG67062.1 - 0.34 10.3 16.4 0.37 10.2 16.4 1.0 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG67062.1 - 0.46 8.7 8.6 0.48 8.7 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG67062.1 - 0.56 8.2 22.1 0.6 8.1 22.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 GBG67062.1 - 1.8 6.9 7.8 1.8 6.9 7.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Utp14 PF04615.13 GBG67062.1 - 3.3 6.1 7.9 3.6 6.1 7.9 1.1 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 GBG67062.1 - 9.5 5.4 16.1 10 5.3 16.1 1.1 1 0 0 1 1 1 0 BUD22 Myb_DNA-bind_4 PF13837.6 GBG67063.1 - 2.4e-09 37.5 0.4 5.7e-09 36.2 0.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67063.1 - 0.0068 16.7 0.3 0.015 15.6 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Lactonase PF10282.9 GBG67063.1 - 0.067 12.4 0.0 0.29 10.3 0.0 1.9 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Ndc1_Nup PF09531.10 GBG67063.1 - 9.2 4.8 11.7 13 4.3 11.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L37e PF01907.19 GBG67064.1 - 8.9e-27 93.0 9.0 1.7e-26 92.2 9.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e C1_1 PF00130.22 GBG67064.1 - 0.045 13.6 2.1 0.079 12.9 2.1 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1258 PF06869.12 GBG67064.1 - 0.1 12.1 0.7 0.12 11.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) HypA PF01155.19 GBG67064.1 - 0.11 12.6 0.7 0.15 12.1 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 GBG67064.1 - 0.12 12.5 1.8 0.17 12.1 1.8 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn-ribbon_8 PF09723.10 GBG67064.1 - 0.18 11.9 1.7 0.34 11.1 1.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Ribosomal_S14 PF00253.21 GBG67064.1 - 0.19 11.5 0.2 0.19 11.5 0.2 2.6 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e DDE_Tnp_4 PF13359.6 GBG67065.1 - 7.1e-15 55.0 0.0 1.9e-13 50.4 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67065.1 - 6.9e-07 29.1 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DUF659 PF04937.15 GBG67067.1 - 2.6e-18 66.3 0.0 7e-10 39.0 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG67067.1 - 0.00081 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Voldacs PF03517.13 GBG67068.1 - 0.79 9.8 7.9 0.048 13.8 0.8 2.4 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling DDE_Tnp_4 PF13359.6 GBG67069.1 - 1.5e-31 109.2 0.0 3.3e-31 108.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67069.1 - 2.5e-14 53.4 0.0 4.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67069.1 - 0.00051 19.7 0.0 0.11 12.1 0.0 3.0 3 0 0 3 3 3 2 Transposase DDE domain DUF1180 PF06679.12 GBG67070.1 - 0.1 13.0 6.6 0.3 11.5 6.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SPX PF03105.19 GBG67070.1 - 0.14 12.1 4.2 0.18 11.7 4.2 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 GBG67070.1 - 3.8 6.3 7.2 5.4 5.8 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DDE_Tnp_4 PF13359.6 GBG67073.1 - 1.8e-08 34.2 0.0 2.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67073.1 - 4.9e-07 29.5 0.0 7.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG67075.1 - 1.2e-07 31.9 2.0 3.9e-07 30.4 0.3 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG67075.1 - 0.083 13.2 0.1 0.35 11.1 0.1 2.1 1 1 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67075.1 - 0.17 12.3 1.7 0.25 11.7 0.6 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG67075.1 - 0.35 11.1 2.2 1 9.6 2.2 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain MULE PF10551.9 GBG67077.1 - 1.6e-17 63.7 0.0 2.9e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 GBG67077.1 - 5.9e-05 22.1 0.1 9.2e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 Transposase, Mutator family CDC45 PF02724.14 GBG67077.1 - 0.086 11.1 9.7 0.12 10.7 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG67077.1 - 1.6 6.8 8.3 2.2 6.4 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG67077.1 - 8 4.4 13.7 12 3.8 13.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-bind_4 PF13837.6 GBG67080.1 - 8.1e-11 42.2 8.1 1.4e-10 41.4 8.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MatB PF16449.5 GBG67080.1 - 0.097 12.5 0.0 23 4.7 0.0 2.6 2 0 0 2 2 2 0 Fimbrillin MatB DBD_Tnp_Mut PF03108.15 GBG67081.1 - 2e-07 30.9 0.1 5.7e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 MuDR family transposase SPX PF03105.19 GBG67082.1 - 0.24 11.3 6.1 0.24 11.3 6.1 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 GBG67082.1 - 0.89 8.3 3.2 0.82 8.4 3.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 GBG67082.1 - 5 6.2 14.7 6.6 5.8 14.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein QWRF PF04484.12 GBG67082.1 - 9.2 5.9 11.3 12 5.5 11.3 1.2 1 0 0 1 1 1 0 QWRF family Hamartin PF04388.12 GBG67082.1 - 9.7 4.7 7.5 11 4.5 7.5 1.1 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 GBG67083.1 - 3 6.9 10.9 4.1 6.5 10.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 GBG67083.1 - 5.4 6.8 6.2 7.3 6.4 6.2 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 GBG67084.1 - 2.8 7.0 25.2 4 6.5 25.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 GBG67084.1 - 5.9 5.5 9.3 10 4.7 9.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RVT_1 PF00078.27 GBG67085.1 - 1.1e-27 97.1 0.1 1.6e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67085.1 - 2.1e-24 85.4 0.0 4.4e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67085.1 - 3e-23 82.1 0.0 5e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67085.1 - 5.7e-17 61.6 1.7 2.1e-16 59.7 0.6 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG67085.1 - 0.032 14.5 0.4 0.085 13.1 0.4 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RuvX PF03652.15 GBG67087.1 - 1.5e-30 106.4 0.0 4e-30 105.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction resolvase Retrotrans_gag PF03732.17 GBG67087.1 - 0.00023 21.4 0.1 0.00023 21.4 0.1 2.5 2 1 0 2 2 2 1 Retrotransposon gag protein ATG16 PF08614.11 GBG67087.1 - 0.3 11.3 18.3 1 9.5 17.9 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4695 PF15766.5 GBG67087.1 - 0.43 10.8 9.6 0.53 10.5 3.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) DUF445 PF04286.12 GBG67087.1 - 5.9 6.6 12.4 15 5.2 12.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) V_ATPase_I PF01496.19 GBG67087.1 - 7 4.4 5.3 13 3.6 5.3 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exo_endo_phos PF03372.23 GBG67088.1 - 0.00087 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RecO_N PF11967.8 GBG67088.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Recombination protein O N terminal PARP PF00644.20 GBG67090.1 - 4.2e-43 147.2 0.0 9e-43 146.1 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 GBG67090.1 - 6.2e-18 65.2 0.0 9.9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PADR1 PF08063.12 GBG67090.1 - 1.5e-12 47.1 1.1 2.9e-12 46.2 1.1 1.4 1 0 0 1 1 1 1 PADR1 (NUC008) domain WGR PF05406.15 GBG67090.1 - 2.1e-08 34.1 0.1 4.7e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 GBG67090.1 - 7.5e-08 32.6 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Glyco_transf_8 PF01501.20 GBG67090.1 - 2.5e-06 27.3 0.0 3.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 BRCT_2 PF16589.5 GBG67090.1 - 2.4e-05 24.6 0.0 6.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_4 PF13837.6 GBG67091.1 - 7.8e-12 45.4 2.6 1.1e-11 44.9 0.8 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67091.1 - 0.0016 18.7 0.5 0.0051 17.1 0.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG67091.1 - 0.35 11.0 4.4 0.73 9.9 4.4 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain BHD_2 PF10404.9 GBG67092.1 - 0.84 10.6 5.7 2.1 9.4 5.4 1.8 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 2 SGT1 PF07093.11 GBG67094.1 - 2.8e-129 432.2 32.8 1.6e-76 258.0 0.0 5.9 3 2 2 5 5 5 5 SGT1 protein BSP_II PF05432.11 GBG67094.1 - 0.0054 16.5 26.0 0.0054 16.5 26.0 3.9 4 0 0 4 4 4 3 Bone sialoprotein II (BSP-II) His_Phos_1 PF00300.22 GBG67094.1 - 3.7 7.2 7.9 7.8 6.1 3.5 2.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) ThylakoidFormat PF11264.8 GBG67095.1 - 5.2e-59 199.5 0.0 6.8e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Thylakoid formation protein M_domain PF12938.7 GBG67095.1 - 0.13 12.0 2.7 0.17 11.7 1.0 1.9 2 0 0 2 2 2 0 M domain of GW182 PPP4R2 PF09184.11 GBG67096.1 - 1.4 8.4 14.8 2 7.9 14.8 1.2 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 GBG67096.1 - 2 8.1 27.8 0.2 11.4 18.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SUIM_assoc PF16619.5 GBG67097.1 - 0.23 11.6 20.1 1.3e+02 2.8 20.1 3.0 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GBG67097.1 - 0.43 10.2 17.6 0.73 9.4 17.6 1.3 1 0 0 1 1 1 0 Spt20 family FAM76 PF16046.5 GBG67097.1 - 0.52 9.6 7.9 2.3 7.5 1.7 2.2 2 0 0 2 2 2 0 FAM76 protein SKA1 PF07160.12 GBG67097.1 - 0.68 9.7 9.5 1 9.2 9.5 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Presenilin PF01080.17 GBG67097.1 - 3.8 6.2 8.4 5.1 5.7 8.4 1.2 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 GBG67097.1 - 6.3 5.7 10.9 8.7 5.2 10.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 GBG67097.1 - 9.2 6.2 5.8 16 5.4 5.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dabb PF07876.12 GBG67100.1 - 2.8e-27 95.2 0.0 5.9e-11 42.9 0.0 3.3 3 0 0 3 3 3 3 Stress responsive A/B Barrel Domain SRC-1 PF08832.10 GBG67100.1 - 0.25 12.4 0.1 0.25 12.4 0.1 3.6 4 0 0 4 4 4 0 Steroid receptor coactivator MBOAT PF03062.19 GBG67101.1 - 4.6e-43 147.9 11.6 1.3e-42 146.5 11.6 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RWD PF05773.22 GBG67102.1 - 4.7e-15 55.9 0.0 7.3e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 GBG67102.1 - 0.00042 20.8 2.0 0.00059 20.3 0.1 2.1 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 VEFS-Box PF09733.9 GBG67102.1 - 0.041 13.7 1.3 0.078 12.8 1.3 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Amidohydro_1 PF01979.20 GBG67102.1 - 0.15 11.3 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family HTH_Tnp_1 PF01527.20 GBG67102.1 - 0.31 11.4 1.4 0.98 9.8 0.0 2.4 3 0 0 3 3 3 0 Transposase PCI PF01399.27 GBG67103.1 - 2.6e-14 53.6 1.4 6.1e-14 52.4 1.4 1.7 1 0 0 1 1 1 1 PCI domain PTS_IIA PF02255.16 GBG67103.1 - 0.015 15.3 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Drf_FH3 PF06367.16 GBG67103.1 - 0.039 13.6 0.1 0.08 12.5 0.1 1.5 1 0 0 1 1 1 0 Diaphanous FH3 Domain Mito_fiss_reg PF05308.11 GBG67105.1 - 0.62 10.1 8.8 0.97 9.5 8.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator RT_RNaseH_2 PF17919.1 GBG67106.1 - 2.7e-24 85.1 0.0 4.9e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67106.1 - 4.6e-23 81.5 0.0 1.1e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67109.1 - 6e-05 22.7 0.0 9.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67110.1 - 3.8e-13 49.3 0.3 7.6e-13 48.4 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG67110.1 - 0.057 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 H2C2 zinc finger CDP-OH_P_transf PF01066.21 GBG67111.1 - 2e-14 54.1 1.0 4.7e-14 52.9 1.0 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase gag-asp_proteas PF13975.6 GBG67111.1 - 8.2e-06 26.3 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67111.1 - 0.0001 22.9 0.0 0.0002 21.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG67111.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease MIT_LIKE_ACTX PF17556.2 GBG67111.1 - 0.12 13.0 0.3 0.29 11.7 0.3 1.6 1 0 0 1 1 1 0 MIT-like atracotoxin family DUF1758 PF05585.12 GBG67111.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG67113.1 - 3.3e-49 167.4 0.4 5.2e-27 94.8 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67113.1 - 1.5e-34 118.0 0.0 3.3e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67113.1 - 4.8e-29 100.7 0.1 2.1e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG67113.1 - 2.2e-18 66.4 0.0 5e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67113.1 - 7.1e-11 42.6 0.0 1.1e-05 25.9 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG67113.1 - 1.2e-08 35.4 0.0 0.00012 22.5 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG67113.1 - 0.0002 21.1 0.0 0.095 12.5 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease PEX-2N PF09263.10 GBG67113.1 - 0.28 11.5 1.1 2.3 8.6 0.5 2.5 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal RT_RNaseH_2 PF17919.1 GBG67114.1 - 4.7e-32 110.0 0.1 1.1e-30 105.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67114.1 - 1.1e-25 89.9 0.1 3.2e-25 88.4 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG67114.1 - 1.7e-06 28.5 0.0 3.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67114.1 - 5e-05 23.9 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG67114.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) zf-CCHC_3 PF13917.6 GBG67114.1 - 0.012 15.5 0.8 0.026 14.5 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 GBG67114.1 - 0.016 15.0 0.0 0.088 12.6 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG67114.1 - 0.025 14.8 0.0 0.082 13.2 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein NIR_SIR PF01077.22 GBG67114.1 - 0.026 14.0 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain RVP_2 PF08284.11 GBG67114.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG67116.1 - 6.8e-19 68.1 0.3 1.1e-18 67.5 0.3 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67116.1 - 4.3e-11 42.7 0.1 8.2e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2862 PF11061.8 GBG67116.1 - 0.054 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) Retrotrans_gag PF03732.17 GBG67117.1 - 0.0089 16.3 1.4 0.027 14.7 0.1 2.3 2 1 1 3 3 3 1 Retrotransposon gag protein Uds1 PF15456.6 GBG67117.1 - 0.013 15.7 0.8 0.13 12.4 0.1 2.6 2 0 0 2 2 2 0 Up-regulated During Septation zf-CCHC_2 PF13696.6 GBG67117.1 - 0.053 13.4 0.6 0.082 12.7 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle ZapB PF06005.12 GBG67118.1 - 0.0044 17.4 5.8 0.0044 17.4 5.8 3.7 3 1 0 3 3 3 1 Cell division protein ZapB Prominin PF05478.11 GBG67118.1 - 0.11 10.5 2.0 0.16 9.9 2.0 1.2 1 0 0 1 1 1 0 Prominin COMP PF11598.8 GBG67118.1 - 1.1 9.7 5.6 3.3 8.2 5.6 1.8 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein RVT_1 PF00078.27 GBG67119.1 - 9.1e-53 179.0 2.3 9.1e-27 94.0 0.0 2.6 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67119.1 - 3.9e-20 72.1 0.0 1.1e-19 70.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67119.1 - 1.1e-19 70.3 0.0 4.1e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG67119.1 - 4.4e-08 33.6 4.1 7.4e-08 32.9 0.0 2.9 2 1 1 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67119.1 - 4.5e-07 30.3 6.1 5.6e-07 30.0 0.0 3.2 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67119.1 - 0.00017 21.4 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67119.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF4399 PF14347.6 GBG67119.1 - 0.015 15.6 0.0 1.6 9.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) IpgD PF05925.12 GBG67119.1 - 0.15 10.6 0.0 0.36 9.3 0.0 1.6 2 0 0 2 2 2 0 Enterobacterial virulence protein IpgD Miga PF10265.9 GBG67119.1 - 0.74 8.7 3.2 1.3 7.9 3.2 1.3 1 0 0 1 1 1 0 Mitoguardin RVT_1 PF00078.27 GBG67120.1 - 4.5e-25 88.5 0.1 7.5e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG67120.1 - 0.0021 17.9 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG67120.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease OxoDH_E1alpha_N PF12573.8 GBG67120.1 - 0.022 14.5 0.4 9.1 6.1 0.0 3.6 4 0 0 4 4 4 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal gag-asp_proteas PF13975.6 GBG67121.1 - 4.2e-07 30.4 0.0 0.00034 21.1 0.0 3.1 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67121.1 - 0.00014 22.5 0.2 0.0048 17.5 0.0 3.0 3 0 0 3 3 3 1 Aspartyl protease TMEM247 PF15444.6 GBG67121.1 - 0.017 15.2 0.1 0.051 13.6 0.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 RVP_2 PF08284.11 GBG67121.1 - 0.018 14.8 0.0 0.097 12.4 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease CENP-K PF11802.8 GBG67121.1 - 0.19 11.3 3.3 0.37 10.3 3.3 1.4 1 0 0 1 1 1 0 Centromere-associated protein K DUF1758 PF05585.12 GBG67121.1 - 0.37 10.6 1.6 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 GBG67122.1 - 8.5e-28 96.3 0.0 1.9e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67122.1 - 2.3e-24 85.7 0.0 5.1e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67122.1 - 7.2e-11 42.0 0.1 1.4e-07 31.3 0.1 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG67122.1 - 5.6e-08 33.3 0.0 1.2e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67122.1 - 7.4e-07 29.7 0.0 1.9e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG67122.1 - 7.7e-07 29.1 0.1 1.9e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG67122.1 - 2.9e-05 23.9 0.0 5.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67122.1 - 0.00022 21.0 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG67122.1 - 0.00046 20.4 0.1 0.0015 18.7 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG67122.1 - 0.004 17.4 0.8 0.021 15.1 0.3 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Peptidase_C14 PF00656.22 GBG67123.1 - 1.3e-41 143.2 0.0 2.3e-40 139.1 0.0 2.2 1 1 0 1 1 1 1 Caspase domain Retrotrans_gag PF03732.17 GBG67124.1 - 0.33 11.3 3.3 0.88 9.9 0.8 3.0 2 1 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG67125.1 - 1.3e-29 103.3 0.1 2.2e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67125.1 - 3.8e-28 97.5 0.0 1.3e-12 47.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67125.1 - 9.5e-28 96.6 0.0 2.2e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67125.1 - 8.2e-16 57.9 0.1 1.7e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG67125.1 - 0.00011 22.4 0.0 0.00042 20.5 0.1 2.0 2 0 0 2 2 2 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG67126.1 - 5.7e-25 87.3 0.0 1e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67126.1 - 1.3e-22 80.0 0.0 3.6e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67126.1 - 0.00036 20.1 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M50B PF13398.6 GBG67127.1 - 0.037 13.7 0.0 0.037 13.7 0.0 2.3 2 1 1 3 3 3 0 Peptidase M50B-like Peptidase_M41 PF01434.18 GBG67127.1 - 0.056 13.3 1.2 0.42 10.4 1.2 2.2 1 1 0 1 1 1 0 Peptidase family M41 Ipi1_N PF12333.8 GBG67127.1 - 0.097 13.3 1.8 0.5 11.0 0.0 2.7 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Miga PF10265.9 GBG67127.1 - 3.1 6.7 14.4 4.9 6.0 14.4 1.2 1 0 0 1 1 1 0 Mitoguardin RT_RNaseH_2 PF17919.1 GBG67128.1 - 6.7e-34 115.9 0.0 1.3e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67128.1 - 4e-30 104.2 0.1 9.7e-30 103.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67128.1 - 1.2e-14 54.1 0.0 2.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67128.1 - 8.1e-11 41.9 0.3 1.4e-10 41.1 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG67128.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG67128.1 - 0.0013 18.9 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG67129.1 - 4.1e-27 94.2 0.0 8.1e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67129.1 - 4e-25 88.1 0.0 1.4e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67129.1 - 2e-18 66.2 0.4 5.8e-18 64.8 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67129.1 - 2.5e-17 63.1 0.2 5.7e-15 55.4 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67129.1 - 6.1e-10 39.3 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG67129.1 - 0.006 17.1 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67129.1 - 0.01 16.4 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG67129.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG67130.1 - 2.2e-22 79.3 0.0 1.3e-20 73.6 0.0 3.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67130.1 - 2e-21 75.9 0.0 1.7e-20 72.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67130.1 - 5.2e-13 49.2 0.0 1.2e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG67130.1 - 1.5e-12 47.5 0.0 3.7e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG67130.1 - 0.0021 18.6 0.0 0.0047 17.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67130.1 - 0.0073 16.9 0.0 0.019 15.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG67130.1 - 0.029 14.7 0.0 0.088 13.1 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG67130.1 - 0.054 13.8 0.1 0.054 13.8 0.1 2.4 2 1 0 3 3 3 0 Retrotransposon gag protein rve_3 PF13683.6 GBG67130.1 - 0.082 12.7 0.0 0.29 11.0 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain RRM_1 PF00076.22 GBG67131.1 - 0.027 14.3 0.0 0.12 12.2 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_phi PF04931.13 GBG67131.1 - 0.7 7.9 28.8 1.4 6.9 28.8 1.4 1 0 0 1 1 1 0 DNA polymerase phi APC_u9 PF16633.5 GBG67131.1 - 4.6 8.4 13.1 0.21 12.7 2.2 3.4 3 0 0 3 3 3 0 Unstructured region on APC between 1st two creatine-rich regions RT_RNaseH_2 PF17919.1 GBG67132.1 - 2.6e-23 81.9 0.0 5.6e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67132.1 - 7.8e-22 77.5 0.0 1.1e-20 73.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG67132.1 - 0.0032 18.0 0.0 0.0089 16.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG67132.1 - 0.01 16.1 0.2 0.065 13.5 0.1 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG67132.1 - 0.014 16.0 0.0 0.039 14.6 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease ACT_3 PF10000.9 GBG67132.1 - 0.081 12.9 0.6 0.36 10.8 0.1 2.4 2 0 0 2 2 2 0 ACT domain RVP PF00077.20 GBG67132.1 - 0.096 13.0 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67132.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease EAF PF09816.9 GBG67134.1 - 5.4e-15 55.6 0.0 9.4e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Peptidase_C48 PF02902.19 GBG67136.1 - 8.1e-08 32.4 1.7 1.6e-07 31.4 1.7 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pkinase PF00069.25 GBG67137.1 - 1e-37 130.0 0.0 1.8e-29 102.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ribonuc_2-5A PF06479.12 GBG67137.1 - 2e-25 89.4 0.2 7.2e-25 87.6 0.1 2.0 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 GBG67137.1 - 4.3e-22 78.6 0.0 6.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 GBG67137.1 - 3.1e-06 26.8 0.0 0.0004 20.2 0.0 3.3 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 GBG67137.1 - 0.0001 22.0 0.7 0.47 10.0 0.0 3.1 1 1 3 4 4 4 3 PQQ-like domain Pkinase_fungal PF17667.1 GBG67137.1 - 0.00018 20.4 0.0 0.00053 18.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GBG67137.1 - 0.0016 17.9 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family V_ATPase_prox PF18274.1 GBG67137.1 - 0.0054 16.7 0.2 0.66 10.0 0.0 3.3 3 0 0 3 3 3 1 Vacuolar ATPase Subunit I N-terminal proximal lobe PQQ_3 PF13570.6 GBG67137.1 - 0.0054 17.2 0.6 10 6.7 0.0 4.4 4 1 0 4 4 4 1 PQQ-like domain DUF659 PF04937.15 GBG67139.1 - 4.1e-06 26.7 0.0 6.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG67140.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Apc13p PF05839.11 GBG67140.1 - 9.1 6.6 6.1 1.4 9.2 0.4 2.4 2 0 0 2 2 2 0 Apc13p protein RT_RNaseH_2 PF17919.1 GBG67141.1 - 1.4e-26 92.4 0.0 2.7e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67141.1 - 1.3e-24 86.5 0.0 2.4e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67141.1 - 8.2e-19 67.5 0.7 2.8e-18 65.7 0.5 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67141.1 - 6e-10 39.0 0.1 1.1e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67141.1 - 2.7e-09 37.3 0.0 8.9e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG67141.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG67142.1 - 1.5e-05 25.6 0.0 7.6e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67142.1 - 6.2e-05 23.5 0.0 0.00022 21.7 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67142.1 - 0.00035 20.3 0.0 0.00095 18.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67142.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG67142.1 - 0.0035 17.6 0.1 0.017 15.4 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4132 PF13569.6 GBG67142.1 - 0.0059 16.4 1.2 0.34 10.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4132) RVT_1 PF00078.27 GBG67143.1 - 1.3e-40 139.3 0.6 1.1e-27 97.1 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67143.1 - 7.4e-19 67.6 0.0 2.6e-18 65.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67143.1 - 1.4e-09 38.2 0.0 1.7e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Trans_reg_C PF00486.28 GBG67143.1 - 0.16 12.1 1.2 24 5.1 0.1 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal DUF3510 PF12022.8 GBG67143.1 - 0.42 11.0 4.7 13 6.1 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3510) Syntaxin-6_N PF09177.11 GBG67143.1 - 0.45 11.1 3.4 18 5.9 0.7 3.8 3 1 0 3 3 3 0 Syntaxin 6, N-terminal P4Ha_N PF08336.11 GBG67143.1 - 0.62 10.1 6.0 3.3 7.7 0.1 3.5 3 1 1 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RT_RNaseH_2 PF17919.1 GBG67144.1 - 5e-27 93.9 0.0 1.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67144.1 - 1.2e-17 64.1 0.0 2.7e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67145.1 - 3.3e-73 242.7 2.6 3.1e-27 94.9 0.1 3.6 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67145.1 - 1.7e-63 210.9 0.0 3.3e-24 84.8 0.0 3.9 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67145.1 - 2.8e-50 168.3 9.9 1.9e-16 59.9 0.7 3.5 3 0 0 3 3 3 3 Integrase zinc binding domain rve PF00665.26 GBG67145.1 - 2e-14 53.8 0.3 1.5e-08 34.9 0.0 3.1 3 0 0 3 3 3 2 Integrase core domain zf-H2C2 PF09337.10 GBG67145.1 - 4.9e-09 36.3 0.7 0.051 13.8 0.0 3.7 3 0 0 3 3 3 3 H2C2 zinc finger RVP_2 PF08284.11 GBG67145.1 - 1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67145.1 - 7.9e-05 23.2 0.0 0.00023 21.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67145.1 - 0.0027 18.3 0.0 0.014 15.9 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF2862 PF11061.8 GBG67145.1 - 0.045 13.6 0.3 2.7 7.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2862) Phage_GPO PF05929.11 GBG67145.1 - 2.3 7.8 8.1 10 5.7 0.0 2.7 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG67146.1 - 3.8e-57 190.5 0.0 5.3e-29 100.2 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67146.1 - 4e-55 184.6 0.0 3.1e-29 101.3 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67146.1 - 4.4e-09 36.2 0.2 0.00022 20.8 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) FTHFS PF01268.19 GBG67146.1 - 0.2 9.8 2.7 0.32 9.2 2.7 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase RT_RNaseH_2 PF17919.1 GBG67147.1 - 2.8e-26 91.5 0.0 4.9e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67147.1 - 2.1e-24 85.8 0.0 3.8e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67147.1 - 8.2e-18 64.3 0.2 2.8e-17 62.5 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG67147.1 - 8.1e-10 38.9 0.0 2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG67147.1 - 0.0034 16.9 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG67147.1 - 0.0076 16.4 0.2 0.16 12.2 0.0 2.6 2 0 0 2 2 2 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG67148.1 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67148.1 - 0.0016 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase B2-adapt-app_C PF09066.10 GBG67148.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain RVT_1 PF00078.27 GBG67150.1 - 1e-09 38.3 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Jnk-SapK_ap_N PF09744.9 GBG67150.1 - 0.00039 20.7 6.5 0.0015 18.7 6.5 2.0 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 EnY2 PF10163.9 GBG67150.1 - 0.0036 17.7 1.8 0.019 15.3 0.1 2.7 2 0 0 2 2 2 1 Transcription factor e(y)2 YqzH PF14164.6 GBG67150.1 - 0.14 12.2 0.2 0.37 10.9 0.2 1.6 1 0 0 1 1 1 0 YqzH-like protein Atg14 PF10186.9 GBG67150.1 - 0.27 10.3 4.7 0.49 9.4 4.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 GBG67150.1 - 0.98 9.8 6.0 1.3 9.5 3.6 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF659 PF04937.15 GBG67151.1 - 9.4e-18 64.5 0.0 1.6e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG67152.1 - 3e-09 37.1 0.0 4.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG67152.1 - 0.012 16.2 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG67152.1 - 0.027 14.8 0.0 0.098 13.0 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67152.1 - 0.076 13.7 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.6 GBG67152.1 - 0.093 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 GBG67153.1 - 1.4e-06 28.8 0.0 3.8e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67153.1 - 0.00017 22.2 0.0 0.00046 20.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG67153.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease cNMP_binding PF00027.29 GBG67153.1 - 0.099 12.7 0.0 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain DUF1043 PF06295.12 GBG67155.1 - 0.0016 18.5 12.0 0.0016 18.5 12.0 2.4 1 1 1 2 2 1 1 Protein of unknown function (DUF1043) Leu_zip PF15294.6 GBG67155.1 - 0.0055 16.3 14.2 0.0055 16.3 14.2 2.1 1 1 1 2 2 2 2 Leucine zipper HIP1_clath_bdg PF16515.5 GBG67155.1 - 0.0059 17.2 35.9 1.2 9.8 11.5 3.3 1 1 2 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 GBG67155.1 - 0.014 16.0 27.7 0.34 11.5 2.7 3.1 2 1 1 3 3 3 0 Initiation control protein YabA DHR10 PF18595.1 GBG67155.1 - 0.016 15.2 21.1 0.016 15.2 21.1 2.9 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Rx_N PF18052.1 GBG67155.1 - 0.044 14.1 2.2 0.044 14.1 2.2 3.3 1 1 2 3 3 3 0 Rx N-terminal domain FAM117 PF15388.6 GBG67155.1 - 0.048 13.1 6.4 0.065 12.7 6.4 1.4 1 0 0 1 1 1 0 Protein Family FAM117 DUF1192 PF06698.11 GBG67155.1 - 0.072 13.2 7.0 3.2 7.9 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) betaPIX_CC PF16523.5 GBG67155.1 - 0.078 12.8 19.7 0.23 11.3 3.8 3.6 1 1 1 3 3 3 0 betaPIX coiled coil GIT_CC PF16559.5 GBG67155.1 - 0.12 12.2 0.4 0.12 12.2 0.4 5.4 3 2 2 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Erp_C PF06780.11 GBG67155.1 - 0.12 12.4 0.7 0.23 11.5 0.4 1.4 1 1 0 1 1 1 0 Erp protein C-terminus TPR_MLP1_2 PF07926.12 GBG67155.1 - 0.21 11.7 40.6 0.096 12.8 22.8 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FUSC PF04632.12 GBG67155.1 - 0.36 9.3 25.2 0.5 8.8 25.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.8 GBG67155.1 - 0.5 10.6 36.5 0.35 11.1 9.9 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Vps54_N PF10475.9 GBG67155.1 - 0.61 9.3 12.1 1.2 8.3 5.3 2.3 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex ATG16 PF08614.11 GBG67155.1 - 0.69 10.1 43.1 1.4 9.1 16.0 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TFIIA PF03153.13 GBG67155.1 - 1 9.2 19.8 1.3 9.0 19.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ADIP PF11559.8 GBG67155.1 - 1.2 9.2 41.1 0.089 12.9 8.2 3.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding LRS4 PF10422.9 GBG67155.1 - 1.4 8.4 21.6 0.36 10.4 17.2 1.8 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 GAS PF13851.6 GBG67155.1 - 2.2 7.6 36.9 0.17 11.2 20.1 2.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 GBG67155.1 - 2.3 8.4 30.9 2.9 8.0 5.7 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 GBG67155.1 - 3.3 8.1 32.7 2.5 8.5 19.0 2.1 1 1 1 2 2 2 0 Fez1 UPF0242 PF06785.11 GBG67155.1 - 3.4 7.7 36.4 1.4 9.0 24.3 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Surfac_D-trimer PF09006.11 GBG67155.1 - 3.8 7.5 11.5 4.4 7.3 1.2 3.4 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation PRKG1_interact PF15898.5 GBG67155.1 - 4.2 8.3 35.2 9.7 7.2 9.1 3.7 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain Herpes_UL6 PF01763.16 GBG67155.1 - 4.5 5.7 16.0 2 6.8 2.1 2.1 2 0 0 2 2 2 0 Herpesvirus UL6 like FapA PF03961.13 GBG67155.1 - 4.6 5.7 21.1 0.12 10.9 10.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A YgaB PF14182.6 GBG67155.1 - 4.9 7.6 21.4 1.3 9.5 5.0 3.2 1 1 1 3 3 3 0 YgaB-like protein DUF4201 PF13870.6 GBG67155.1 - 7 6.4 30.5 2 8.1 4.8 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) CENP-H PF05837.12 GBG67155.1 - 7.9 6.9 37.0 5.1 7.5 5.7 3.1 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Ran-binding PF05508.11 GBG67155.1 - 8.4 5.3 13.5 1.7 7.5 8.6 2.0 1 1 2 3 3 3 0 RanGTP-binding protein Spc7 PF08317.11 GBG67155.1 - 9.6 5.0 35.7 5.8 5.7 19.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DMSP_lyase PF16867.5 GBG67155.1 - 9.7 5.8 10.0 0.68 9.6 3.2 2.1 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase RVT_1 PF00078.27 GBG67157.1 - 0.0055 16.3 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-FCS PF06467.14 GBG67157.1 - 2.4 8.1 4.9 0.4 10.6 0.3 2.0 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RT_RNaseH_2 PF17919.1 GBG67158.1 - 4.8e-15 55.4 0.0 1.2e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67158.1 - 8.8e-14 51.7 0.0 4.8e-13 49.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67158.1 - 4.9e-10 39.6 0.0 1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG67158.1 - 0.00018 22.0 0.0 0.00049 20.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67158.1 - 0.00049 20.7 0.0 0.0014 19.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG67158.1 - 0.0023 17.5 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG67158.1 - 0.064 13.5 0.2 0.22 11.8 0.2 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG67159.1 - 1.5e-61 204.7 1.2 3.3e-32 110.5 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67159.1 - 6.4e-48 161.4 0.0 1.1e-27 96.4 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67159.1 - 1.1e-06 28.8 0.0 5.3e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain U1snRNP70_N PF12220.8 GBG67159.1 - 0.43 11.2 2.8 3 8.5 1.4 2.9 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RT_RNaseH_2 PF17919.1 GBG67160.1 - 6e-33 112.9 0.1 1.2e-32 111.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67160.1 - 1.8e-20 73.2 0.0 3.9e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67160.1 - 4.2e-15 56.0 0.0 9.9e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG67160.1 - 5.9e-12 45.5 0.0 5.9e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67160.1 - 1.6e-10 40.9 0.2 2.6e-10 40.2 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67161.1 - 1.3e-23 82.9 0.0 3.5e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67161.1 - 7.1e-20 71.3 0.0 2.7e-19 69.4 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67161.1 - 6.4e-17 61.4 0.2 2.3e-16 59.6 0.2 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67161.1 - 2.8e-16 59.7 0.0 5.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_2 PF07719.17 GBG67161.1 - 9e-15 53.5 22.1 0.0059 16.6 0.0 9.9 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 GBG67161.1 - 6.1e-11 41.6 6.4 0.0035 17.4 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG67161.1 - 2e-09 36.9 16.9 9e-06 25.3 0.1 6.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG67161.1 - 1.1e-06 28.2 4.3 0.00058 19.7 0.0 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG67161.1 - 9.5e-06 25.3 10.9 0.01 15.7 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat BTB PF00651.31 GBG67161.1 - 0.0003 21.0 0.0 0.00084 19.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain TPR_16 PF13432.6 GBG67161.1 - 0.00069 20.2 24.6 0.015 15.9 0.2 6.7 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG67161.1 - 0.0011 18.6 2.7 0.0062 16.2 0.0 3.8 5 0 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 GBG67161.1 - 0.0017 18.6 1.5 21 5.8 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG67161.1 - 0.01 15.9 14.0 1.7 8.8 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Chromo PF00385.24 GBG67161.1 - 0.011 15.6 0.1 0.027 14.4 0.1 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TPR_12 PF13424.6 GBG67161.1 - 0.012 15.9 0.0 0.012 15.9 0.0 7.6 8 2 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG67161.1 - 8.9 6.6 17.0 8.2 6.7 0.1 4.9 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 CemA PF03040.14 GBG67163.1 - 2.7e-68 230.3 0.1 3.5e-68 230.0 0.1 1.1 1 0 0 1 1 1 1 CemA family RVT_1 PF00078.27 GBG67164.1 - 6.3e-31 107.6 0.2 1.4e-30 106.4 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67164.1 - 9.9e-24 83.3 0.0 2.5e-23 82.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67164.1 - 1.6e-23 83.0 0.0 3.9e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG67164.1 - 2.1e-08 34.7 0.0 7.3e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG67164.1 - 2.6e-08 33.7 0.0 5.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG67164.1 - 1.6e-06 28.6 0.0 5.3e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG67164.1 - 0.008 16.0 0.0 0.036 13.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG67164.1 - 0.011 16.0 1.9 0.092 13.0 0.0 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein RVP PF00077.20 GBG67164.1 - 0.14 12.5 0.0 0.46 10.8 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease ADIP PF11559.8 GBG67164.1 - 8.7 6.4 11.7 0.57 10.3 5.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MEKHLA PF08670.11 GBG67165.1 - 2.4e-33 115.0 0.2 4.2e-33 114.2 0.2 1.3 1 0 0 1 1 1 1 MEKHLA domain START PF01852.19 GBG67166.1 - 2.1e-23 82.9 0.0 1.1e-13 51.1 0.0 2.2 1 1 1 2 2 2 2 START domain Homeodomain PF00046.29 GBG67166.1 - 3.7e-16 58.7 0.6 8.8e-16 57.5 0.6 1.7 1 0 0 1 1 1 1 Homeodomain bZIP_1 PF00170.21 GBG67166.1 - 0.00026 21.0 7.6 0.00056 20.0 7.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor JIP_LZII PF16471.5 GBG67166.1 - 0.0084 16.3 1.2 0.017 15.3 1.2 1.4 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II Cnn_1N PF07989.11 GBG67166.1 - 0.039 14.1 2.3 0.094 12.9 2.3 1.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Homeobox_KN PF05920.11 GBG67166.1 - 0.12 12.3 0.3 0.12 12.3 0.3 1.9 2 0 0 2 2 2 0 Homeobox KN domain Ribosomal_L32e PF01655.18 GBG67167.1 - 2.6e-49 166.1 1.3 3.1e-49 165.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Integrase_H2C2 PF17921.1 GBG67168.1 - 1.2e-17 63.8 1.6 2.2e-17 62.9 1.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG67168.1 - 2.6e-12 46.9 0.0 5.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67168.1 - 6.6e-10 39.2 0.0 5.3e-08 33.1 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG67168.1 - 1.9e-09 37.4 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG67168.1 - 0.0039 17.4 0.4 0.0078 16.4 0.4 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG67171.1 - 4.4e-18 65.6 0.0 7.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67171.1 - 3.2e-12 46.4 0.0 7.1e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67171.1 - 0.062 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG67173.1 - 0.002 18.7 0.0 0.0036 17.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67173.1 - 0.044 14.4 0.0 0.099 13.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease TFIIF_alpha PF05793.12 GBG67173.1 - 7.8 5.0 16.1 13 4.2 16.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 GBG67173.1 - 8.2 5.6 21.8 15 4.8 18.1 2.0 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 GBG67173.1 - 8.8 4.4 14.3 15 3.6 14.3 1.3 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L23 PF00276.20 GBG67177.1 - 6.4e-11 42.5 1.4 1.6e-10 41.2 1.4 1.6 1 1 0 1 1 1 1 Ribosomal protein L23 gag-asp_proteas PF13975.6 GBG67178.1 - 0.00032 21.2 0.1 0.00064 20.2 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67178.1 - 0.013 16.1 0.1 0.027 15.1 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG67178.1 - 0.015 15.1 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease ATE_N PF04376.13 GBG67178.1 - 0.041 14.3 0.1 0.59 10.6 0.0 2.5 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus RVP_2 PF08284.11 GBG67178.1 - 0.054 13.3 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG67179.1 - 7.2e-67 225.1 0.5 1.1e-34 119.9 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67179.1 - 3.9e-36 123.1 0.0 5.9e-21 74.4 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67179.1 - 3.9e-17 62.5 0.0 1.2e-12 48.0 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG67179.1 - 1.4e-11 44.8 0.0 0.00011 22.7 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67179.1 - 5.5e-11 42.9 0.0 7.3e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG67179.1 - 1.3e-10 41.2 0.0 0.00059 19.6 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67179.1 - 5.2e-05 23.0 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease DUF1758 PF05585.12 GBG67179.1 - 0.0037 17.1 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Retrotrans_gag PF03732.17 GBG67179.1 - 0.083 13.2 5.8 0.18 12.1 0.4 4.0 4 0 0 4 4 4 0 Retrotransposon gag protein DUF2151 PF10221.9 GBG67179.1 - 8.4 4.8 15.8 15 4.1 15.8 1.4 1 0 0 1 1 1 0 Cell cycle and development regulator Ycf1 PF05758.12 GBG67179.1 - 8.7 4.1 10.5 15 3.3 10.5 1.2 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.12 GBG67180.1 - 0.035 12.3 22.9 0.053 11.7 22.9 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG67180.1 - 3.2 6.3 31.2 12 4.4 31.2 1.8 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Retrotrans_gag PF03732.17 GBG67181.1 - 0.00033 20.9 1.0 0.013 15.7 0.0 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein DUF2781 PF10914.8 GBG67181.1 - 0.042 14.3 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF1041 PF06292.17 GBG67181.1 - 0.048 14.1 2.8 0.21 12.0 2.8 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1041) DUF4407 PF14362.6 GBG67181.1 - 0.068 12.5 7.5 0.2 11.0 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MOSC_N PF03476.16 GBG67181.1 - 0.1 12.5 0.5 0.23 11.4 0.5 1.5 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain Flot PF15975.5 GBG67181.1 - 2.1 8.5 11.0 3.9 7.7 11.0 1.5 1 0 0 1 1 1 0 Flotillin DltD PF04914.12 GBG67182.1 - 0.069 12.5 0.1 0.37 10.1 0.1 1.9 1 1 0 1 1 1 0 DltD protein LRR_RI_capping PF18779.1 GBG67182.1 - 0.35 10.6 1.3 0.73 9.5 0.0 2.1 2 0 0 2 2 2 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Retrotrans_gag PF03732.17 GBG67183.1 - 0.0011 19.3 0.2 0.0011 19.3 0.2 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG67183.1 - 0.0045 16.7 0.9 0.013 15.3 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) PK PF00224.21 GBG67184.1 - 1.1e-45 156.0 2.3 3.2e-43 148.0 1.1 2.2 1 1 1 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG67184.1 - 6.6e-15 55.4 0.0 2.5e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GBG67184.1 - 0.0048 16.0 0.1 0.0084 15.3 0.1 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RVT_1 PF00078.27 GBG67187.1 - 3.6e-27 95.3 0.1 7.3e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67187.1 - 2.3e-25 88.5 0.0 5.1e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67187.1 - 2.5e-23 82.4 0.0 5e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67187.1 - 2.3e-20 72.5 0.1 4.8e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG67187.1 - 6e-07 29.7 0.0 1.7e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG67187.1 - 0.0033 17.7 0.1 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG67187.1 - 0.023 14.9 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Radical_SAM PF04055.21 GBG67188.1 - 2.4e-32 112.6 0.0 7.2e-32 111.1 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 GBG67188.1 - 1.1e-28 99.1 0.0 2.7e-28 97.9 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 GBG67188.1 - 1.1e-10 41.4 0.0 1e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 TRAM domain CCDC53 PF10152.9 GBG67188.1 - 0.093 13.1 1.8 1.2 9.6 0.1 2.9 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex PRIMA1 PF16101.5 GBG67188.1 - 0.11 12.5 10.8 0.56 10.3 10.8 2.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1860 PF08949.10 GBG67188.1 - 3.5 7.3 7.5 0.6 9.8 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) Ribosomal_60s PF00428.19 GBG67188.1 - 6.5 7.4 6.6 18 6.0 6.6 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein AA_kinase PF00696.28 GBG67190.1 - 3.5e-48 164.3 6.0 4.6e-48 163.9 6.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family CDC45 PF02724.14 GBG67191.1 - 4 5.6 9.8 5.6 5.1 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG67191.1 - 8.5 5.6 16.0 13 5.0 16.0 1.1 1 0 0 1 1 1 0 BUD22 DUF659 PF04937.15 GBG67192.1 - 1.9e-05 24.6 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4835 PF16119.5 GBG67194.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) MyTH4 PF00784.17 GBG67196.1 - 3.8e-18 66.0 0.0 1.3e-17 64.2 0.0 2.0 1 0 0 1 1 1 1 MyTH4 domain Presenilin PF01080.17 GBG67197.1 - 0.016 14.0 11.1 0.023 13.4 11.1 1.4 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 GBG67197.1 - 0.41 9.0 2.5 0.52 8.7 2.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 GBG67197.1 - 2 6.6 18.6 2.7 6.2 18.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 GBG67197.1 - 8.4 6.4 5.6 11 6.0 5.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-CCHC PF00098.23 GBG67198.1 - 0.021 14.9 8.3 0.039 14.0 8.3 1.5 1 0 0 1 1 1 0 Zinc knuckle APC_N_CC PF16689.5 GBG67198.1 - 0.21 11.7 9.7 5.9 7.0 1.9 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain DUF3464 PF11947.8 GBG67198.1 - 0.97 9.2 3.2 2.5 7.8 3.2 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MyTH4 PF00784.17 GBG67199.1 - 1e-16 61.4 0.0 3.3e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 MyTH4 domain OAM_dimer PF16554.5 GBG67199.1 - 1.2 9.7 19.7 0.18 12.3 0.2 6.8 8 0 0 8 8 8 0 Dimerisation domain of d-ornithine 4,5-aminomutase NOA36 PF06524.12 GBG67199.1 - 2.7 7.2 5.8 7.3 5.8 5.8 1.6 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GBG67199.1 - 5.2 7.5 10.5 0.19 12.1 1.4 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Peptidase_C48 PF02902.19 GBG67203.1 - 3e-08 33.8 0.2 5.7e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Phage_Gp15 PF06854.11 GBG67204.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Gp15 protein TMEM247 PF15444.6 GBG67205.1 - 0.1 12.7 0.1 0.1 12.7 0.1 1.6 2 0 0 2 2 2 0 Transmembrane protein 247 DUF4407 PF14362.6 GBG67205.1 - 0.13 11.6 5.8 0.18 11.1 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MscS_TM PF12794.7 GBG67205.1 - 2.9 6.7 7.5 2.4 6.9 0.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 CAF1 PF04857.20 GBG67207.1 - 5.5e-39 134.2 0.2 8.2e-39 133.6 0.2 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease TAT_signal PF10518.9 GBG67207.1 - 0.014 15.2 1.1 0.014 15.2 1.1 2.5 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence PIN_12 PF16289.5 GBG67208.1 - 0.14 12.7 5.7 0.39 11.2 5.7 1.8 1 0 0 1 1 1 0 PIN domain UPF0184 PF03670.13 GBG67208.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) DUF1840 PF08895.11 GBG67208.1 - 3.1 8.2 13.1 0.41 11.0 7.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) Macoilin PF09726.9 GBG67208.1 - 5.7 5.4 17.7 8.9 4.7 17.7 1.2 1 0 0 1 1 1 0 Macoilin family CAF1 PF04857.20 GBG67209.1 - 2.6e-31 109.0 0.1 4.7e-31 108.2 0.0 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease Wzy_C PF04932.15 GBG67209.1 - 0.051 13.2 7.3 0.1 12.2 7.3 1.4 1 0 0 1 1 1 0 O-Antigen ligase Cwf_Cwc_15 PF04889.12 GBG67209.1 - 7.9 6.1 12.9 13 5.4 12.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein IFT57 PF10498.9 GBG67210.1 - 0.0049 15.9 3.1 0.018 14.1 3.1 1.8 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 NBP1 PF08537.10 GBG67210.1 - 0.0058 16.1 4.0 0.0065 15.9 4.0 1.0 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 EzrA PF06160.12 GBG67210.1 - 0.0081 14.4 2.7 0.0085 14.3 2.7 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA FPP PF05911.11 GBG67210.1 - 0.0085 14.3 5.4 0.011 14.0 5.4 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF745 PF05335.13 GBG67210.1 - 0.0086 15.8 1.1 0.0098 15.6 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF4600 PF15372.6 GBG67210.1 - 0.01 16.3 1.7 0.013 15.9 1.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4600) YscO PF07321.12 GBG67210.1 - 0.013 15.4 6.8 0.14 12.1 5.7 2.0 1 1 0 1 1 1 0 Type III secretion protein YscO Laminin_II PF06009.12 GBG67210.1 - 0.031 14.3 0.7 0.037 14.0 0.7 1.1 1 0 0 1 1 1 0 Laminin Domain II Lebercilin PF15619.6 GBG67210.1 - 0.084 12.5 7.8 0.11 12.1 7.8 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin_2 PF01920.20 GBG67210.1 - 0.11 12.4 3.0 0.39 10.7 0.8 2.0 2 0 0 2 2 2 0 Prefoldin subunit Cnn_1N PF07989.11 GBG67210.1 - 0.18 12.0 6.8 1.8 8.8 2.1 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Bcr-Abl_Oligo PF09036.10 GBG67210.1 - 0.2 11.7 7.0 0.79 9.8 0.1 3.1 1 1 3 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain UPF0449 PF15136.6 GBG67210.1 - 0.64 10.5 5.4 1.4 9.4 3.4 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 CCDC-167 PF15188.6 GBG67210.1 - 0.89 9.9 5.2 15 6.0 5.3 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Myb_DNA-bind_4 PF13837.6 GBG67211.1 - 2.6e-08 34.1 0.2 2.6e-08 34.1 0.2 2.2 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67211.1 - 0.066 13.5 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG67212.1 - 6.5e-27 94.1 0.0 1.3e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67212.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67212.1 - 0.13 11.9 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain zf-CCHC PF00098.23 GBG67213.1 - 0.00051 20.0 3.0 0.0009 19.2 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG67213.1 - 0.21 11.3 0.8 0.37 10.6 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4604 PF15377.6 GBG67213.1 - 1 9.7 10.1 1.6 9.1 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF737 PF05300.11 GBG67213.1 - 2.4 8.4 13.8 0.07 13.5 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF737) B9-C2 PF07162.11 GBG67214.1 - 3.2e-44 151.1 0.0 3.8e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Miga PF10265.9 GBG67215.1 - 1.8 7.4 12.6 2 7.3 12.6 1.0 1 0 0 1 1 1 0 Mitoguardin SelP_N PF04592.14 GBG67215.1 - 4.7 6.5 13.0 7.5 5.9 13.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 GBG67215.1 - 7 5.1 20.5 7.8 4.9 20.5 1.0 1 0 0 1 1 1 0 Macoilin family Ras PF00071.22 GBG67217.1 - 2.6e-50 170.2 0.0 3.3e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG67217.1 - 1.2e-29 103.0 0.0 2.1e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG67217.1 - 4.6e-11 42.5 0.0 6.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 GBG67217.1 - 0.00014 22.2 0.0 0.00052 20.4 0.0 1.9 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 GBG67217.1 - 0.00082 19.4 0.0 0.0019 18.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG67217.1 - 0.023 14.6 0.0 4.8 7.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 GBG67217.1 - 0.036 13.9 0.0 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 GBG67217.1 - 0.058 12.8 0.2 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein Gtr1_RagA PF04670.12 GBG67217.1 - 0.064 12.6 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 GBG67217.1 - 0.071 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 GBG67217.1 - 0.072 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GBG67217.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 GBG67217.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 GBG67217.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 GBG67217.1 - 0.14 11.2 1.4 4.3 6.4 0.1 2.6 2 1 0 3 3 3 0 G-protein alpha subunit ArgoMid PF16487.5 GBG67217.1 - 0.15 12.4 0.1 0.28 11.5 0.1 1.5 1 1 0 1 1 1 0 Mid domain of argonaute NB-ARC PF00931.22 GBG67217.1 - 0.17 11.1 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 GBG67217.1 - 0.2 11.9 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.6 GBG67218.1 - 7.8e-13 48.5 6.3 1.6e-12 47.5 6.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GBG67218.1 - 1.3e-10 40.8 3.4 2.4e-10 40.0 3.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GBG67218.1 - 5.6e-10 38.9 4.6 1e-09 38.1 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG67218.1 - 1.9e-09 37.2 3.9 4.1e-09 36.2 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG67218.1 - 1.6e-07 31.5 4.7 1.6e-07 31.5 4.7 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GBG67218.1 - 3.4e-05 23.7 3.6 5.5e-05 23.0 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GBG67218.1 - 0.0011 18.7 6.3 0.002 17.9 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GBG67218.1 - 0.0015 18.5 2.4 0.0033 17.5 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GBG67218.1 - 0.0033 17.2 4.3 0.0055 16.5 4.3 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 GBG67218.1 - 0.0048 16.9 5.7 0.013 15.5 5.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GBG67218.1 - 0.023 14.6 8.0 0.043 13.7 8.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 GBG67218.1 - 0.054 13.7 2.3 0.12 12.6 2.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 GBG67218.1 - 0.24 11.7 1.9 0.49 10.7 1.9 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 GBG67218.1 - 0.3 11.2 3.5 0.71 10.0 3.5 1.6 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 GBG67218.1 - 0.41 10.3 4.3 1 9.0 4.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GBG67218.1 - 0.59 10.3 5.3 1.5 9.1 5.3 1.7 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 GBG67218.1 - 2.1 8.3 5.1 3.9 7.5 5.1 1.5 1 0 0 1 1 1 0 PHD-finger Trypan_PARP PF05887.11 GBG67218.1 - 6.5 6.7 8.0 16 5.4 7.0 2.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) gag-asp_proteas PF13975.6 GBG67219.1 - 0.0007 20.1 0.1 0.003 18.1 0.1 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG67219.1 - 0.0013 18.5 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG67219.1 - 0.05 14.3 0.1 0.15 12.7 0.1 1.9 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG67219.1 - 0.17 12.0 0.5 0.34 11.1 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG67222.1 - 7.3e-09 35.9 3.1 7.9e-09 35.8 2.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67222.1 - 0.00035 20.8 0.7 0.0055 17.0 0.3 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG67222.1 - 0.0036 17.3 0.2 0.0088 16.1 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Defensin_big PF14862.6 GBG67222.1 - 0.1 12.9 0.1 0.78 10.1 0.0 2.4 2 0 0 2 2 2 0 Big defensin CENP-Q PF13094.6 GBG67223.1 - 0.003 17.8 6.6 0.003 17.8 6.6 2.0 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin_2 PF14523.6 GBG67223.1 - 0.58 10.6 8.5 4.2 7.8 0.4 3.0 1 1 1 2 2 2 0 Syntaxin-like protein LCD1 PF09798.9 GBG67223.1 - 1.7 7.1 6.4 2 6.8 6.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein RVT_1 PF00078.27 GBG67224.1 - 5.3e-32 111.1 0.1 2.9e-31 108.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67224.1 - 3.8e-27 94.2 0.0 1.8e-26 92.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67224.1 - 4.3e-24 84.8 0.0 1.4e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG67224.1 - 5e-08 33.5 0.0 9.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67224.1 - 1.6e-07 31.8 0.0 3.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67224.1 - 2.5e-06 27.3 0.0 6.7e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67224.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease FKBP_C PF00254.28 GBG67225.1 - 2.5e-26 91.8 0.0 3.9e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPPK_C PF12555.8 GBG67225.1 - 1 9.4 7.7 2 8.5 7.7 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal zf-CCHC PF00098.23 GBG67226.1 - 0.055 13.6 2.3 0.095 12.8 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Catalase-rel PF06628.12 GBG67226.1 - 0.089 13.0 0.0 26 5.1 0.0 2.5 2 0 0 2 2 2 0 Catalase-related immune-responsive Topo_Zn_Ribbon PF08272.11 GBG67227.1 - 0.042 13.5 1.9 0.055 13.1 0.3 2.0 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like ATE_N PF04376.13 GBG67227.1 - 0.081 13.3 0.1 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus zf-CCHC PF00098.23 GBG67227.1 - 0.27 11.4 2.0 0.57 10.4 2.0 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG67228.1 - 1.6e-20 73.4 0.0 3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67228.1 - 1.4e-18 66.8 0.0 2.9e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67228.1 - 4.4e-14 52.7 0.0 1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG67228.1 - 2.1e-11 43.7 0.4 6.4e-11 42.2 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67228.1 - 7.1e-11 42.0 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG67228.1 - 2.3e-05 24.8 0.0 6.5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67228.1 - 0.00053 20.6 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG67228.1 - 0.28 11.0 1.6 0.62 9.9 1.6 1.5 1 0 0 1 1 1 0 Aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG67231.1 - 0.0014 18.9 0.3 0.0014 18.9 0.3 2.8 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG67232.1 - 4.2e-31 108.2 0.0 6e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG67233.1 - 0.00017 21.9 0.2 0.00033 21.0 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Ank PF00023.30 GBG67234.1 - 2.1e-07 31.1 0.1 0.00046 20.5 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat zf-CCCH_4 PF18044.1 GBG67234.1 - 1.4e-06 28.0 2.4 1.4e-06 28.0 2.4 2.8 3 0 0 3 3 3 1 CCCH-type zinc finger Ank_2 PF12796.7 GBG67234.1 - 1.4e-06 28.8 0.0 2.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GBG67234.1 - 2.2e-06 27.6 0.0 0.091 13.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat zf-CCCH PF00642.24 GBG67234.1 - 3.8e-06 26.7 3.7 3.8e-06 26.7 3.7 3.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG67234.1 - 3.2e-05 23.8 2.2 3.2e-05 23.8 2.2 2.7 3 0 0 3 3 2 1 Zinc finger domain Ank_4 PF13637.6 GBG67234.1 - 0.00012 22.5 0.0 0.00028 21.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG67234.1 - 0.0093 16.3 0.1 0.51 10.7 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Torus PF16131.5 GBG67234.1 - 0.12 13.1 2.5 0.39 11.4 2.5 1.9 1 0 0 1 1 1 0 Torus domain Glyco_hydro_46 PF01374.18 GBG67234.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 zf-CCCH_2 PF14608.6 GBG67234.1 - 0.36 11.4 13.8 0.73 10.4 0.6 3.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Integrase_H2C2 PF17921.1 GBG67236.1 - 5.6e-15 55.2 0.1 1.2e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG67236.1 - 0.073 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG67237.1 - 1.2e-26 92.6 0.0 2.2e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67237.1 - 2.8e-24 85.4 0.0 4.7e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67237.1 - 2.4e-10 40.3 0.1 3.8e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67237.1 - 0.00085 19.4 0.1 0.0016 18.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG67238.1 - 4.3e-15 56.0 0.1 1.3e-14 54.4 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG67238.1 - 8.7e-12 45.0 1.4 1.4e-11 44.3 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG67238.1 - 0.00081 20.0 0.0 0.0024 18.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67238.1 - 0.0035 17.9 0.0 0.012 16.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67238.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67238.1 - 0.027 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG67238.1 - 0.063 13.6 0.2 0.24 11.7 0.2 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Myotoxins PF00819.17 GBG67238.1 - 0.078 13.3 2.9 0.99 9.7 1.1 2.7 2 0 0 2 2 2 0 Myotoxin, crotamine Corona_nucleoca PF00937.18 GBG67238.1 - 0.24 10.4 3.6 0.5 9.4 3.6 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PRP38_assoc PF12871.7 GBG67238.1 - 4.6 7.9 15.6 17 6.1 15.6 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RVP_2 PF08284.11 GBG67239.1 - 0.00035 20.4 0.0 0.00077 19.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF2749 PF10907.8 GBG67239.1 - 0.013 15.6 0.5 0.27 11.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) SlyX PF04102.12 GBG67239.1 - 0.028 15.0 3.8 0.82 10.3 0.1 2.9 3 0 0 3 3 3 0 SlyX BBS2_N PF14781.6 GBG67239.1 - 0.081 12.8 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal RT_RNaseH_2 PF17919.1 GBG67240.1 - 1.8e-28 98.5 0.0 3.1e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67240.1 - 3.5e-25 88.3 0.0 7.5e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67240.1 - 2.9e-11 43.3 0.1 6.3e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67240.1 - 1.6e-08 34.5 0.1 1.3e-07 31.6 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain LysM PF01476.20 GBG67240.1 - 0.042 13.9 0.1 11 6.2 0.0 2.7 2 0 0 2 2 2 0 LysM domain RT_RNaseH_2 PF17919.1 GBG67241.1 - 1.8e-22 79.2 0.0 3e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67241.1 - 3.3e-21 75.5 0.0 5.9e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67241.1 - 3.1e-05 23.6 0.0 4.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG67241.1 - 2 6.6 3.7 3 6.0 3.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG67242.1 - 2.1e-29 101.5 0.0 4.9e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67242.1 - 1.8e-25 89.2 0.0 4.6e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67242.1 - 8.6e-15 54.6 1.3 2.3e-14 53.2 1.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG67242.1 - 2.7e-13 50.1 0.0 6.9e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF2282 PF10048.9 GBG67244.1 - 0.031 14.3 0.0 0.082 12.9 0.0 1.8 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) Ribosomal_L13 PF00572.18 GBG67245.1 - 1.7e-51 173.7 0.0 2.3e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Retrotrans_gag PF03732.17 GBG67246.1 - 0.001 19.3 2.2 0.0038 17.5 0.1 2.6 2 1 1 3 3 3 1 Retrotransposon gag protein Pep_deformylase PF01327.21 GBG67246.1 - 0.065 12.8 4.3 0.034 13.7 2.1 1.6 2 0 0 2 2 2 0 Polypeptide deformylase Seryl_tRNA_N PF02403.22 GBG67246.1 - 6.7 7.0 12.0 1.7 8.9 5.9 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4446 PF14584.6 GBG67246.1 - 7.8 6.5 5.6 20 5.1 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) FACT-Spt16_Nlob PF14826.6 GBG67247.1 - 8.6e-11 41.9 0.0 2e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain DUF1611_N PF17396.2 GBG67247.1 - 0.038 14.2 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_N) Rossmann-like domain RT_RNaseH_2 PF17919.1 GBG67248.1 - 9.2e-28 96.2 0.0 2.2e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67248.1 - 1.5e-27 96.6 0.0 2.5e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67248.1 - 1.1e-20 73.9 0.0 2.7e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG67248.1 - 4.9e-05 23.5 1.2 0.00024 21.3 0.1 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF659 PF04937.15 GBG67250.1 - 4.5e-32 111.0 0.0 1.1e-31 109.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG67250.1 - 4.2e-07 29.7 0.5 8.8e-07 28.6 0.1 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region COMPASS-Shg1 PF05205.12 GBG67250.1 - 2.3 9.0 5.2 3.6 8.4 2.8 2.4 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 SPT16 PF08644.11 GBG67251.1 - 1.9e-47 161.2 2.1 3.3e-47 160.4 0.0 2.6 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 GBG67251.1 - 3.7e-28 98.6 0.0 6.3e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 GBG67251.1 - 1.2e-17 64.1 0.1 2.7e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PPV_E2_C PF00511.17 GBG67252.1 - 0.12 12.6 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 E2 (early) protein, C terminal Nop14 PF04147.12 GBG67252.1 - 7.3 4.7 51.5 10 4.2 51.5 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 GBG67255.1 - 1.2e-71 242.3 13.3 1.2e-71 242.3 13.3 1.3 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Kinesin PF00225.23 GBG67257.1 - 1.3e-93 313.6 6.9 6.2e-83 278.5 0.1 3.5 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 GBG67257.1 - 5.2e-25 88.1 0.0 3.7e-24 85.4 0.0 2.6 1 0 0 1 1 1 1 Microtubule binding DUF1327 PF07041.11 GBG67257.1 - 0.022 14.8 1.0 0.27 11.3 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1327) Myb_DNA-bind_4 PF13837.6 GBG67258.1 - 2.9e-05 24.4 1.1 4.7e-05 23.7 1.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG67258.1 - 0.00019 21.6 0.1 0.00028 21.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67258.1 - 0.0011 19.3 0.3 0.0019 18.5 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Integrase_H2C2 PF17921.1 GBG67259.1 - 1.9e-06 27.9 0.3 1.9e-06 27.9 0.3 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain zf-CCHC_5 PF14787.6 GBG67259.1 - 0.23 11.2 1.8 0.48 10.2 1.8 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PNISR PF15996.5 GBG67260.1 - 0.0068 16.7 3.9 0.0079 16.5 3.9 1.1 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR Zip PF02535.22 GBG67260.1 - 0.039 13.2 2.3 0.044 13.0 2.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1676 PF07898.13 GBG67260.1 - 0.069 13.2 3.3 0.16 12.0 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) DUF913 PF06025.12 GBG67260.1 - 0.54 9.2 4.4 0.59 9.0 4.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Orf78 PF06024.12 GBG67260.1 - 1.4 9.3 13.5 38 4.7 13.5 2.1 1 1 0 1 1 1 0 Orf78 (ac78) NPR3 PF03666.13 GBG67260.1 - 1.4 7.6 10.5 1.7 7.4 10.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mito_carr PF00153.27 GBG67262.1 - 7.3e-62 205.3 3.4 4.7e-23 80.9 0.0 4.5 4 0 0 4 4 4 4 Mitochondrial carrier protein RVT_1 PF00078.27 GBG67262.1 - 4e-58 196.6 0.1 9.8e-28 97.2 0.0 3.1 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67262.1 - 1.3e-37 128.3 0.0 7.5e-20 71.2 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67262.1 - 2.2e-30 104.7 0.0 3.7e-19 68.6 0.0 3.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67262.1 - 2.4e-18 66.0 0.2 6.5e-18 64.6 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG67262.1 - 1.4e-06 28.9 0.0 4.4e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG67262.1 - 1.5e-06 28.0 0.0 3.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG67262.1 - 5.3e-06 26.9 0.0 1.7e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG67262.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG67262.1 - 0.0074 16.5 0.6 0.039 14.2 0.0 2.6 2 0 0 2 2 1 1 Retrotransposon gag protein Integrin_b_cyt PF08725.11 GBG67262.1 - 0.057 13.1 0.0 4.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain TolA_bind_tri PF16331.5 GBG67262.1 - 0.083 13.0 7.1 2.3 8.3 4.3 3.2 2 0 0 2 2 2 0 TolA binding protein trimerisation rve_3 PF13683.6 GBG67262.1 - 0.089 12.6 0.0 0.47 10.3 0.0 2.3 1 0 0 1 1 1 0 Integrase core domain SlyX PF04102.12 GBG67262.1 - 3.6 8.3 13.1 0.28 11.8 1.4 4.7 4 0 0 4 4 3 0 SlyX Retrotrans_gag PF03732.17 GBG67263.1 - 0.00077 19.7 0.7 0.0036 17.5 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein WTX PF09422.10 GBG67263.1 - 0.0035 16.5 0.8 0.0035 16.5 0.8 1.5 2 0 0 2 2 2 1 WTX protein Fez1 PF06818.15 GBG67263.1 - 0.013 15.9 0.3 0.013 15.9 0.3 2.5 3 0 0 3 3 3 0 Fez1 DUF1664 PF07889.12 GBG67263.1 - 0.033 14.2 1.3 0.16 12.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SKI PF01202.22 GBG67263.1 - 4.5 7.4 6.6 1.5 8.9 0.2 2.6 3 0 0 3 3 3 0 Shikimate kinase DUF659 PF04937.15 GBG67264.1 - 2.8e-23 82.5 0.4 2.5e-22 79.4 0.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG67264.1 - 5.4e-06 26.1 0.1 1.4e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG67265.1 - 7.3e-06 26.5 0.0 1.4e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67265.1 - 0.026 15.1 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG67265.1 - 0.16 11.8 0.8 0.25 11.1 0.8 1.2 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG67267.1 - 1.6e-22 79.4 0.0 3.2e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67267.1 - 4.6e-22 78.3 0.0 1.2e-21 76.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67267.1 - 0.00033 20.2 0.0 0.00061 19.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG67267.1 - 0.0018 18.8 0.0 0.004 17.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG67267.1 - 0.039 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease pXO2-72 PF17443.2 GBG67267.1 - 0.14 12.4 0.1 2 8.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein pXO2-72 Amino_oxidase PF01593.24 GBG67268.1 - 1.3e-52 179.7 0.0 2e-52 179.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG67268.1 - 6.7e-11 42.3 3.7 7.7e-11 42.1 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG67268.1 - 1.9e-08 34.3 3.5 7e-06 25.8 0.4 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GBG67268.1 - 0.00029 20.9 0.5 0.0095 15.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GBG67268.1 - 0.00043 19.7 0.0 0.00065 19.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GBG67268.1 - 0.013 14.4 0.2 0.017 14.0 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 GBG67268.1 - 0.015 14.6 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 GBG67268.1 - 0.057 12.5 1.1 0.089 11.8 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain MCRA PF06100.11 GBG67268.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 MCRA family Pyr_redox_2 PF07992.14 GBG67268.1 - 0.16 11.2 2.9 1.8 7.7 3.3 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DD_K PF12121.8 GBG67269.1 - 1.5 9.0 9.1 1.1 9.4 4.2 2.6 2 0 0 2 2 2 0 Dermaseptin RT_RNaseH PF17917.1 GBG67270.1 - 3.4e-30 104.4 0.0 9.4e-30 103.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67270.1 - 1.9e-29 101.7 0.0 5e-29 100.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Amino_oxidase PF01593.24 GBG67270.1 - 2e-22 80.1 0.0 4.7e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Phage_GPO PF05929.11 GBG67270.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.5 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Casc1_N PF15927.5 GBG67270.1 - 5.2 6.7 35.8 0.45 10.2 13.0 2.6 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus FA_desaturase PF00487.24 GBG67271.1 - 1e-32 114.0 24.7 1.7e-32 113.2 24.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 GBG67271.1 - 1.2e-27 96.8 0.1 2e-27 96.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) RVT_1 PF00078.27 GBG67272.1 - 1.7e-29 103.0 0.1 2.7e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67272.1 - 3.2e-19 68.8 0.1 6.6e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG67272.1 - 1.1e-16 60.7 0.0 9e-16 57.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67272.1 - 8.1e-08 32.5 0.0 2.1e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67272.1 - 1.1e-07 32.0 0.1 3.4e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain LSM PF01423.22 GBG67272.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 LSM domain APG17 PF04108.12 GBG67272.1 - 0.057 12.5 0.1 0.23 10.5 0.0 2.0 2 0 0 2 2 2 0 Autophagy protein Apg17 HrpB7 PF09486.10 GBG67272.1 - 4.1 7.8 8.9 0.77 10.1 3.5 2.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) RVT_1 PF00078.27 GBG67274.1 - 9.3e-34 116.9 0.0 1.4e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67274.1 - 2e-06 28.0 0.1 6.8e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG67275.1 - 3.2e-33 113.7 0.1 6.4e-33 112.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67275.1 - 5.3e-30 103.8 0.2 1e-29 102.9 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67275.1 - 1.8e-29 102.9 0.1 3.5e-29 101.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67275.1 - 7e-18 64.5 0.2 2.6e-17 62.6 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG67275.1 - 3.2e-05 24.4 0.0 0.00024 21.6 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG67275.1 - 4e-05 23.8 0.0 0.00018 21.6 0.0 2.2 1 1 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG67275.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67275.1 - 0.008 16.8 0.0 0.024 15.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG67275.1 - 0.014 15.2 0.9 0.059 13.1 0.0 2.4 3 0 0 3 3 3 0 Putative peptidase (DUF1758) TPR_1 PF00515.28 GBG67276.1 - 1.5e-24 84.7 18.4 1.9e-11 43.3 0.7 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG67276.1 - 2e-21 74.3 16.8 4.7e-09 35.7 0.9 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 GBG67276.1 - 5.7e-16 57.9 12.5 2.4e-07 30.3 0.1 3.6 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 GBG67276.1 - 1.2e-15 56.3 13.7 1e-07 31.6 0.2 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 GBG67276.1 - 7.2e-12 44.5 8.4 4e-06 26.5 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GBG67276.1 - 1.3e-11 44.7 13.0 6.1e-10 39.3 2.4 3.4 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG67276.1 - 4.8e-11 43.1 10.3 2.8e-07 31.1 1.2 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG67276.1 - 7.3e-11 41.7 5.8 7e-06 26.1 0.0 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 GBG67276.1 - 1.8e-10 40.7 9.1 0.0013 19.4 0.2 4.8 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG67276.1 - 3e-08 34.0 9.5 1e-06 29.1 0.4 3.7 2 1 0 3 3 3 1 Tetratricopeptide repeat SGTA_dimer PF16546.5 GBG67276.1 - 1.4e-07 31.1 0.0 3.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_10 PF13374.6 GBG67276.1 - 1.3e-06 28.1 14.5 0.00028 20.7 0.1 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 GBG67276.1 - 4.4e-06 26.8 4.8 0.00089 19.4 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GBG67276.1 - 0.00012 22.1 6.3 0.043 13.9 0.6 3.3 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat SGT1 PF07093.11 GBG67276.1 - 0.00047 18.7 0.0 0.0008 18.0 0.0 1.3 1 0 0 1 1 1 1 SGT1 protein BTAD PF03704.17 GBG67276.1 - 0.0045 17.4 4.7 0.035 14.6 0.4 2.5 1 1 1 2 2 2 1 Bacterial transcriptional activator domain Rota_NSP3 PF01665.16 GBG67276.1 - 0.0054 15.9 0.4 0.26 10.4 0.4 2.1 1 1 0 1 1 1 1 Rotavirus non-structural protein NSP3 ANAPC3 PF12895.7 GBG67276.1 - 0.0084 16.3 5.4 0.04 14.1 4.2 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 GBG67276.1 - 0.0095 15.9 2.0 2.6 8.1 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GBG67276.1 - 0.0099 15.3 0.3 0.92 9.0 0.0 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_6 PF13174.6 GBG67276.1 - 0.011 16.3 9.2 0.48 11.2 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GBG67276.1 - 0.021 14.2 0.8 0.03 13.8 0.6 1.3 1 1 0 1 1 1 0 Coatomer epsilon subunit SPO22 PF08631.10 GBG67276.1 - 0.043 13.3 1.5 7.5 5.9 0.1 2.6 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like MIT PF04212.18 GBG67276.1 - 0.052 13.6 14.7 1.1 9.3 0.2 4.1 2 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 GBG67276.1 - 0.12 12.7 0.8 23 5.5 0.0 3.4 4 0 0 4 4 3 0 PPR repeat Sel1 PF08238.12 GBG67276.1 - 0.17 12.6 4.5 6 7.7 0.6 3.7 2 2 1 3 3 3 0 Sel1 repeat CHDCT2 PF08074.11 GBG67276.1 - 0.18 12.0 0.6 0.36 11.0 0.6 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain SBF2 PF12335.8 GBG67276.1 - 0.25 10.9 3.2 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Myotubularin protein SOAR PF16533.5 GBG67276.1 - 0.27 11.2 2.6 0.55 10.2 2.6 1.4 1 0 0 1 1 1 0 STIM1 Orai1-activating region Totivirus_coat PF05518.11 GBG67276.1 - 0.45 8.5 3.5 0.72 7.8 3.5 1.3 1 0 0 1 1 1 0 Totivirus coat protein zf-C4H2 PF10146.9 GBG67276.1 - 0.46 10.8 6.8 1.6 9.0 0.1 2.8 3 0 0 3 3 3 0 Zinc finger-containing protein RPN7 PF10602.9 GBG67276.1 - 1.4 8.6 6.4 0.56 9.9 0.1 2.2 1 1 1 2 2 2 0 26S proteasome subunit RPN7 Hepcidin PF06446.12 GBG67277.1 - 0.012 16.0 4.2 0.028 14.8 4.2 1.6 1 0 0 1 1 1 0 Hepcidin DUF4412 PF14371.6 GBG67277.1 - 0.044 13.6 0.4 0.21 11.4 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4412) FAIM1 PF06905.13 GBG67277.1 - 0.21 11.3 0.2 0.34 10.6 0.2 1.3 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Retrotrans_gag PF03732.17 GBG67279.1 - 0.00088 19.5 1.0 0.00088 19.5 1.0 3.0 1 1 2 3 3 3 1 Retrotransposon gag protein FlxA PF14282.6 GBG67279.1 - 0.014 15.4 1.2 0.014 15.4 1.2 2.0 3 0 0 3 3 3 0 FlxA-like protein DUF4703 PF15775.5 GBG67280.1 - 0.12 12.1 1.8 0.13 12.0 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Myb_DNA-bind_4 PF13837.6 GBG67281.1 - 3.3e-06 27.4 1.4 6.5e-06 26.4 1.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG67281.1 - 0.014 15.5 0.8 0.032 14.4 0.8 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Chloroplast_duf PF14476.6 GBG67281.1 - 0.9 8.5 7.1 1.4 7.8 7.1 1.2 1 0 0 1 1 1 0 Petal formation-expressed Chloroplast_duf PF14476.6 GBG67282.1 - 0.091 11.7 7.1 0.12 11.3 7.1 1.1 1 0 0 1 1 1 0 Petal formation-expressed Herpes_ICP4_N PF03584.15 GBG67282.1 - 7.6 6.3 10.3 5.1 6.9 1.0 2.6 1 1 2 3 3 3 0 Herpesvirus ICP4-like protein N-terminal region RVT_1 PF00078.27 GBG67283.1 - 3.3e-27 95.4 0.2 5.5e-27 94.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67283.1 - 3.4e-25 88.0 0.0 1e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67283.1 - 7.5e-24 84.0 0.0 2e-23 82.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG67283.1 - 3.1e-06 27.0 0.0 5.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG67283.1 - 1.3e-05 25.6 0.0 2.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67283.1 - 3.5e-05 24.4 0.0 8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG67283.1 - 0.00043 20.1 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG67284.1 - 2.8e-23 82.2 2.8 3e-22 78.9 2.8 2.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67284.1 - 2.2e-19 69.3 0.2 5.2e-19 68.1 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG67284.1 - 3.3e-18 65.6 0.6 4.4e-15 55.5 0.6 2.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SMC_N PF02463.19 GBG67284.1 - 4.9e-13 49.0 10.2 8.6e-12 45.0 10.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain rve PF00665.26 GBG67284.1 - 5.9e-11 42.6 0.0 2e-10 40.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain AAA_23 PF13476.6 GBG67284.1 - 2.8e-10 41.0 0.0 2.8e-10 41.0 0.0 7.6 4 4 1 6 6 3 1 AAA domain AAA_21 PF13304.6 GBG67284.1 - 3e-07 30.6 2.1 0.025 14.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GBG67284.1 - 9.6e-05 22.1 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain zf-H2C2 PF09337.10 GBG67284.1 - 0.00053 20.1 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger NACHT PF05729.12 GBG67284.1 - 0.004 17.1 0.0 0.016 15.1 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GBG67284.1 - 0.026 14.9 0.0 0.026 14.9 0.0 3.5 3 1 0 3 3 2 0 AAA ATPase domain AAA_15 PF13175.6 GBG67284.1 - 0.03 14.0 0.0 0.03 14.0 0.0 4.2 3 1 0 4 4 4 0 AAA ATPase domain ABC_tran PF00005.27 GBG67284.1 - 0.038 14.5 0.0 0.038 14.5 0.0 4.8 4 1 0 4 4 4 0 ABC transporter AAA_25 PF13481.6 GBG67284.1 - 0.07 12.7 0.1 0.07 12.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 GBG67284.1 - 0.83 10.1 3.0 1.5 9.2 0.0 3.1 3 0 0 3 3 2 0 RNA helicase Pec_lyase_C PF00544.19 GBG67285.1 - 1.3e-21 77.2 0.3 8.4e-21 74.5 0.3 1.9 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG67285.1 - 4e-06 26.8 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Right handed beta helix region DUF4957 PF16318.5 GBG67285.1 - 0.005 16.8 0.0 0.021 14.8 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4957) RT_RNaseH_2 PF17919.1 GBG67286.1 - 4.8e-17 61.8 0.8 1e-16 60.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67286.1 - 9.8e-10 38.7 0.1 3.2e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67286.1 - 3.4e-09 36.6 0.0 6.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG67286.1 - 8.7e-07 29.5 0.0 2.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67286.1 - 1.8e-06 28.4 0.0 7.2e-06 26.5 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67286.1 - 3.3e-05 23.7 0.0 8.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG67286.1 - 0.00071 19.4 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG67286.1 - 0.02 15.1 0.3 0.083 13.2 0.3 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG67287.1 - 3.6e-31 108.4 0.1 5.8e-27 94.6 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PilN PF05137.13 GBG67287.1 - 0.0019 18.3 0.0 1.1 9.4 0.0 3.5 3 1 1 4 4 4 1 Fimbrial assembly protein (PilN) DFF-C PF09033.10 GBG67287.1 - 0.033 14.1 0.3 0.058 13.3 0.3 1.3 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain DUF3584 PF12128.8 GBG67287.1 - 0.036 11.6 0.8 0.052 11.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HutP PF09021.11 GBG67288.1 - 0.14 12.5 0.9 0.29 11.4 0.9 1.5 1 0 0 1 1 1 0 HutP DUF1482 PF07358.11 GBG67288.1 - 0.27 11.2 1.3 0.73 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1482) Annexin PF00191.20 GBG67289.1 - 3.7e-43 145.4 0.1 2.1e-14 53.3 0.0 4.2 4 0 0 4 4 4 4 Annexin YL1 PF05764.13 GBG67292.1 - 1.2 9.2 8.0 0.089 12.9 2.2 2.1 3 0 0 3 3 3 0 YL1 nuclear protein AIM3 PF17096.5 GBG67292.1 - 2.8 8.9 5.0 1.3 10.0 1.5 2.3 3 0 0 3 3 3 0 Altered inheritance of mitochondria protein 3 Pkinase_Tyr PF07714.17 GBG67293.1 - 4.2e-34 118.0 0.0 1.8e-33 115.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG67293.1 - 6.3e-31 107.7 0.0 1.2e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG67293.1 - 1.2e-05 25.4 0.0 0.00051 20.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG67293.1 - 0.011 14.6 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_M48 PF01435.18 GBG67294.1 - 1.5e-31 109.7 0.1 3.4e-31 108.6 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.6 GBG67294.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain SYCP2_SLD PF18584.1 GBG67294.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Synaptonemal complex 2 Spt16M-like domain HrcA_DNA-bdg PF03444.15 GBG67294.1 - 0.2 11.4 0.2 25 4.6 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding YCF90 PF17088.5 GBG67294.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family Nop14 PF04147.12 GBG67295.1 - 0.84 7.8 19.7 1.1 7.4 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_4 PF13837.6 GBG67296.1 - 6.4e-08 32.9 0.2 1.8e-07 31.4 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67296.1 - 0.091 13.1 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CENP-B_dimeris PF09026.10 GBG67297.1 - 0.0054 17.1 4.0 0.0054 17.1 4.0 2.4 2 0 0 2 2 2 1 Centromere protein B dimerisation domain BUD22 PF09073.10 GBG67297.1 - 0.02 14.3 24.1 0.023 14.1 24.1 1.0 1 0 0 1 1 1 0 BUD22 Spt5_N PF11942.8 GBG67297.1 - 0.023 15.7 7.7 0.023 15.7 7.7 2.5 2 0 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4834 PF16118.5 GBG67297.1 - 0.048 14.6 2.0 0.048 14.6 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Mak16 PF04874.14 GBG67297.1 - 0.15 12.7 31.8 0.63 10.7 14.5 2.1 2 0 0 2 2 2 0 Mak16 protein C-terminal region CobT PF06213.12 GBG67297.1 - 0.38 10.1 28.1 0.52 9.6 14.2 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.14 GBG67297.1 - 0.51 10.1 21.2 1.9 8.2 2.6 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Prothymosin PF03247.14 GBG67297.1 - 0.67 10.4 54.0 0.51 10.8 14.9 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family NOA36 PF06524.12 GBG67297.1 - 0.77 9.0 31.1 0.4 10.0 13.8 2.1 2 0 0 2 2 2 0 NOA36 protein Presenilin PF01080.17 GBG67297.1 - 2.3 6.9 12.1 2.6 6.7 12.1 1.0 1 0 0 1 1 1 0 Presenilin DUF3306 PF11748.8 GBG67297.1 - 4 8.3 14.6 3.9 8.4 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF4366 PF14283.6 GBG67297.1 - 4.5 7.3 13.0 0.62 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Zip PF02535.22 GBG67297.1 - 5 6.2 10.2 2.6 7.2 0.3 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.14 GBG67297.1 - 5.1 7.5 12.6 4.4 7.7 5.0 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 DARPP-32 PF05395.12 GBG67297.1 - 7.7 6.7 24.7 8.1 6.6 12.5 2.1 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 Serinc PF03348.15 GBG67297.1 - 7.7 5.3 7.3 13 4.5 7.3 1.4 1 1 0 1 1 1 0 Serine incorporator (Serinc) DUF4715 PF15835.5 GBG67298.1 - 0.12 12.5 9.1 1.2 9.2 9.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) PPP4R2 PF09184.11 GBG67299.1 - 0.074 12.6 14.5 0.12 11.9 14.5 1.4 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 GBG67299.1 - 0.096 12.0 12.9 0.13 11.6 12.9 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG67299.1 - 0.12 10.5 19.9 0.16 10.1 19.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG67299.1 - 0.32 10.4 17.3 0.43 9.9 17.3 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG67299.1 - 0.99 7.6 13.6 1.3 7.2 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG67299.1 - 1.5 6.8 24.1 1.9 6.5 24.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 GBG67299.1 - 1.9 6.4 10.4 1.2 7.2 8.6 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DDE_Tnp_4 PF13359.6 GBG67300.1 - 2.2e-31 108.7 0.0 3.5e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67300.1 - 1.8e-14 53.9 0.0 2.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67300.1 - 0.00031 20.5 0.1 0.97 9.0 0.1 2.5 2 0 0 2 2 2 2 Transposase DDE domain CDC45 PF02724.14 GBG67300.1 - 0.022 13.1 12.2 0.03 12.6 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG67300.1 - 0.032 13.7 19.4 0.05 13.0 19.4 1.3 1 0 0 1 1 1 0 SDA1 Drc1-Sld2 PF11719.8 GBG67300.1 - 0.16 11.5 8.9 0.22 11.1 8.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein BUD22 PF09073.10 GBG67300.1 - 2.1 7.6 26.9 3.1 7.0 26.9 1.2 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.13 GBG67300.1 - 3.2 6.7 25.8 4.8 6.1 25.8 1.1 1 0 0 1 1 1 0 Paf1 MCM_bind PF09739.9 GBG67300.1 - 5 5.4 6.4 6.9 5.0 6.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Mpp10 PF04006.12 GBG67300.1 - 5.5 5.3 30.7 9.2 4.6 30.7 1.3 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG67300.1 - 5.7 5.0 28.0 7.8 4.6 28.0 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG67300.1 - 8.1 5.1 9.5 12 4.6 9.5 1.1 1 0 0 1 1 1 0 Presenilin Myb_DNA-bind_4 PF13837.6 GBG67301.1 - 9.9e-10 38.7 0.5 1.5e-08 34.9 0.3 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG67301.1 - 0.011 15.8 0.5 0.035 14.2 0.5 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2950 PF11453.8 GBG67302.1 - 0.087 12.0 3.3 0.098 11.8 3.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2950) RVT_1 PF00078.27 GBG67305.1 - 6.2e-27 94.6 0.1 9.7e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_20 PF12840.7 GBG67305.1 - 0.086 12.9 0.1 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain F-box-like PF12937.7 GBG67306.1 - 6.5e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.18 GBG67306.1 - 1.1e-06 28.7 15.8 5e-06 26.5 15.8 2.3 1 0 0 1 1 1 1 MYND finger Sel1 PF08238.12 GBG67306.1 - 3.5e-06 27.5 4.6 0.46 11.2 0.1 4.5 4 0 0 4 4 4 2 Sel1 repeat PRP38_assoc PF12871.7 GBG67307.1 - 0.084 13.5 14.5 0.1 13.2 14.5 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term CDC45 PF02724.14 GBG67307.1 - 0.13 10.5 9.1 0.15 10.4 9.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG67307.1 - 0.64 8.2 11.6 0.64 8.2 11.6 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG67307.1 - 0.94 8.8 11.6 1.1 8.6 11.6 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG67307.1 - 1.8 7.2 5.7 2.2 7.0 5.7 1.0 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 GBG67307.1 - 2.4 6.6 5.9 2.8 6.4 5.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Paf1 PF03985.13 GBG67307.1 - 8.1 5.3 16.9 10 5.0 16.9 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 GBG67307.1 - 8.9 6.0 9.6 10 5.8 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Integrase_H2C2 PF17921.1 GBG67308.1 - 3.2e-05 24.0 0.1 5.4e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG67308.1 - 0.0076 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 H2C2 zinc finger Nop53 PF07767.11 GBG67308.1 - 0.01 15.3 19.9 0.015 14.7 19.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cwf_Cwc_15 PF04889.12 GBG67308.1 - 0.13 12.0 23.3 0.19 11.4 23.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GBG67308.1 - 0.65 9.3 27.2 0.84 8.9 27.2 1.1 1 0 0 1 1 1 0 BUD22 Na_trans_assoc PF06512.13 GBG67308.1 - 1 9.6 16.4 2.1 8.6 16.3 1.6 1 1 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG67308.1 - 2 6.5 29.5 2.8 6.1 29.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG67308.1 - 2.6 6.2 23.1 3.4 5.8 23.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 GBG67308.1 - 9.9 6.5 16.2 15 5.8 16.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Integrase_H2C2 PF17921.1 GBG67309.1 - 1.7e-19 69.6 0.1 3.3e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67309.1 - 1.1e-09 38.2 0.1 2.1e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67309.1 - 1.9e-09 37.7 0.0 5.9e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG67309.1 - 1.1e-07 31.7 0.0 2.9e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67309.1 - 1.3e-05 25.7 0.0 3.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67309.1 - 0.0028 18.2 0.0 0.01 16.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG67309.1 - 0.0036 17.5 0.0 0.025 14.8 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG67310.1 - 2e-13 50.5 0.0 4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain AdoHcyase PF05221.17 GBG67310.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase zf-CCHC PF00098.23 GBG67311.1 - 0.0057 16.7 1.3 0.0057 16.7 1.3 2.7 2 0 0 2 2 2 2 Zinc knuckle RVT_1 PF00078.27 GBG67312.1 - 3.2e-33 115.1 0.0 6.1e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67312.1 - 1e-28 99.3 0.0 3.4e-28 97.6 0.0 2.0 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67312.1 - 1.8e-28 98.9 0.4 5.2e-28 97.4 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67312.1 - 1.6e-19 69.8 0.3 3.5e-19 68.7 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG67312.1 - 1.9e-17 63.6 0.0 5.3e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG67312.1 - 3.6e-06 26.8 0.0 7.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67312.1 - 0.00013 22.5 0.0 0.00031 21.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG67312.1 - 0.0013 18.9 0.1 0.0032 17.6 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG67312.1 - 0.0037 17.8 0.0 0.0096 16.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SbcD_C PF12320.8 GBG67312.1 - 0.078 13.3 0.0 2 8.7 0.0 3.0 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain RasGEF_N PF00618.20 GBG67312.1 - 0.11 12.7 0.0 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 RasGEF N-terminal motif ADP_ribosyl_GH PF03747.14 GBG67312.1 - 0.12 12.1 0.1 3.5 7.3 0.1 2.8 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase DUF1758 PF05585.12 GBG67312.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF1444 PF07285.11 GBG67312.1 - 0.29 10.7 1.0 0.66 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1444) DUF659 PF04937.15 GBG67313.1 - 4.4e-18 65.6 0.0 6.1e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Glyco_hydro_42C PF08533.10 GBG67314.1 - 0.022 14.4 0.0 0.081 12.7 0.0 1.9 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain DUF3437 PF11919.8 GBG67314.1 - 0.068 13.1 0.2 1.1 9.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) RT_RNaseH_2 PF17919.1 GBG67315.1 - 1.6e-27 95.5 0.0 3.2e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67315.1 - 5.6e-25 87.7 0.0 1.2e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67315.1 - 5.6e-19 68.0 0.4 1.9e-18 66.3 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67315.1 - 1.1e-16 61.1 0.0 1.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67315.1 - 1.9e-09 37.7 0.0 5.3e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG67315.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG67317.1 - 2.2e-26 92.4 0.0 4.2e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67317.1 - 1.2e-14 54.4 0.0 1.8e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67317.1 - 0.00053 19.7 0.3 0.077 12.6 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG67317.1 - 0.021 15.2 0.0 0.057 13.8 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain Pro-MCH PF05824.12 GBG67317.1 - 0.13 12.2 0.4 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) VirionAssem_T7 PF11653.8 GBG67319.1 - 2 9.0 6.1 0.55 10.8 2.7 1.8 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein DDE_Tnp_4 PF13359.6 GBG67320.1 - 7.1e-31 107.0 0.0 5.4e-30 104.1 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67320.1 - 8.1e-18 64.8 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67320.1 - 1.2e-07 31.6 0.0 0.011 15.4 0.0 3.3 3 0 0 3 3 3 3 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG67325.1 - 1.1e-24 86.3 0.0 1.6e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67325.1 - 1.3e-20 73.7 0.0 1.7e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67326.1 - 1.6e-32 112.8 0.1 2.5e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG67326.1 - 1.1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67326.1 - 2.7e-05 24.7 0.0 6.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67326.1 - 0.0014 19.2 0.0 0.006 17.1 0.0 2.2 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG67326.1 - 0.0019 18.0 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG67326.1 - 0.11 12.3 0.0 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease PA26 PF04636.13 GBG67326.1 - 1.6 7.5 9.6 2.6 6.9 9.6 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RVT_1 PF00078.27 GBG67328.1 - 1.9e-33 115.8 0.1 3.2e-33 115.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67328.1 - 2.2e-22 79.0 0.0 9.5e-22 76.9 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67328.1 - 8.9e-13 48.4 0.0 2.9e-12 46.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PTH2 PF01981.16 GBG67329.1 - 7e-28 97.3 0.0 4.1e-27 94.8 0.0 2.4 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PTH2 PF01981.16 GBG67330.1 - 9.9e-43 145.2 0.3 9.9e-43 145.2 0.3 2.2 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 RT_RNaseH_2 PF17919.1 GBG67331.1 - 3.4e-27 94.4 0.0 2e-26 92.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67331.1 - 1.3e-25 90.2 0.0 3.1e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67331.1 - 7.6e-25 87.2 0.0 2.6e-24 85.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67331.1 - 3.6e-08 33.6 0.0 1.4e-07 31.7 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG67331.1 - 7.3e-06 26.5 0.0 2.6e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67331.1 - 6.5e-05 23.4 0.0 0.00033 21.2 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67331.1 - 0.00012 21.9 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67331.1 - 0.00043 20.1 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RNR_Alpha PF17975.1 GBG67331.1 - 0.05 14.1 1.1 0.24 11.9 0.0 2.7 3 0 0 3 3 3 0 Ribonucleotide reductase alpha domain Pro_isomerase PF00160.21 GBG67332.1 - 1.1e-06 29.0 0.0 4.8e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAN_4 PF14295.6 GBG67332.1 - 0.00014 21.7 10.4 0.041 13.8 4.4 2.4 2 0 0 2 2 2 2 PAN domain Plasmodium_Vir PF05795.11 GBG67332.1 - 0.39 10.1 12.6 7.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein CDC45 PF02724.14 GBG67332.1 - 1.3 7.2 21.1 2.1 6.5 21.1 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG67332.1 - 1.3 7.5 31.5 2.8 6.4 31.5 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 GBG67332.1 - 4.1 5.5 26.7 6.2 4.9 26.7 1.2 1 0 0 1 1 1 0 Nop14-like family Exostosin PF03016.15 GBG67333.1 - 4.2e-22 78.7 0.4 5.3e-22 78.4 0.4 1.1 1 0 0 1 1 1 1 Exostosin family P2X_receptor PF00864.19 GBG67333.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.2 1 1 0 1 1 1 0 ATP P2X receptor RRM_1 PF00076.22 GBG67334.1 - 1.3e-17 63.3 0.0 2.2e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 GBG67334.1 - 2.4e-05 24.6 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 GBG67334.1 - 0.007 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nab2 PF11517.8 GBG67334.1 - 0.014 15.6 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) RT_RNaseH_2 PF17919.1 GBG67335.1 - 8.1e-24 83.6 0.0 2.3e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67335.1 - 1.5e-21 76.6 0.0 6.1e-21 74.7 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67335.1 - 2.5e-18 66.4 0.0 5.1e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67335.1 - 4.2e-16 58.8 0.6 1.6e-15 56.9 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG67335.1 - 1.7e-08 34.9 0.0 4.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67335.1 - 2.8e-08 34.2 0.0 9.3e-08 32.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG67335.1 - 5.4e-08 33.0 0.0 2.3e-07 31.0 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG67335.1 - 5.6e-08 32.6 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67335.1 - 1.4e-05 24.9 0.0 3.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG67335.1 - 0.083 13.1 0.1 0.81 10.0 0.1 2.5 2 0 0 2 2 2 0 H2C2 zinc finger DUF4187 PF13821.6 GBG67335.1 - 0.41 10.5 5.6 0.057 13.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) SDA1 PF05285.12 GBG67337.1 - 0.058 12.8 13.9 0.074 12.5 13.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG67337.1 - 0.77 7.9 17.4 0.91 7.7 17.4 1.0 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG67338.1 - 3.9e-28 98.5 0.1 6.8e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67338.1 - 2.4e-15 56.3 0.4 6.3e-15 55.0 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG67338.1 - 2.4e-12 47.1 0.1 5.4e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67338.1 - 4.8e-10 39.7 0.3 4.3e-08 33.4 0.2 2.7 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG67338.1 - 1.2e-06 28.5 0.0 2.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG67338.1 - 2e-06 28.2 0.0 8.1e-06 26.3 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67338.1 - 1e-05 26.1 0.0 2.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG67338.1 - 0.00017 21.3 0.0 0.00057 19.7 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67338.1 - 0.00063 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG67338.1 - 0.0032 17.6 0.1 0.0085 16.3 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RR_TM4-6 PF06459.12 GBG67338.1 - 1.1 9.0 34.8 2.6 7.8 34.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 GBG67338.1 - 1.9 6.6 53.0 2.8 6.0 53.0 1.2 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG67338.1 - 3.1 6.1 53.7 4.5 5.6 53.7 1.2 1 0 0 1 1 1 0 Mpp10 protein Ribosomal_L7Ae PF01248.26 GBG67339.1 - 1.7e-26 91.8 0.0 2e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 GBG67339.1 - 0.00014 21.7 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain YadA_stalk PF05662.14 GBG67339.1 - 0.032 14.6 0.8 7.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin RRM_1 PF00076.22 GBG67341.1 - 6e-12 45.2 0.0 1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 GBG67341.1 - 9.2e-07 29.5 0.1 1.7e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 GBG67341.1 - 7.1e-06 25.9 1.6 1.6e-05 24.8 1.6 1.6 1 0 0 1 1 1 1 Zinc finger domain RRM_occluded PF16842.5 GBG67341.1 - 0.00065 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_3 PF15663.5 GBG67341.1 - 0.0046 17.2 0.1 0.0094 16.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger containing family RRM_3 PF08777.11 GBG67341.1 - 0.0049 16.9 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif zf-CCCH PF00642.24 GBG67341.1 - 0.0099 15.8 2.1 0.0099 15.8 2.1 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GBG67341.1 - 0.02 15.3 0.5 0.056 13.9 0.5 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 GBG67341.1 - 0.067 13.0 2.5 0.13 12.1 2.5 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger RRM_1 PF00076.22 GBG67342.1 - 5.5e-12 45.3 0.0 9.2e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 GBG67342.1 - 8.6e-07 29.6 0.1 1.6e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 GBG67342.1 - 7.1e-06 25.9 1.6 1.4e-05 24.9 1.6 1.6 1 0 0 1 1 1 1 Zinc finger domain RRM_occluded PF16842.5 GBG67342.1 - 0.00061 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_3 PF15663.5 GBG67342.1 - 0.0046 17.1 0.1 0.0087 16.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger containing family RRM_3 PF08777.11 GBG67342.1 - 0.0047 17.0 0.0 0.0079 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif zf-CCCH PF00642.24 GBG67342.1 - 0.0048 16.8 2.1 0.0092 15.9 2.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GBG67342.1 - 0.021 15.3 0.5 0.052 14.0 0.5 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 GBG67342.1 - 0.065 13.1 2.5 0.12 12.2 2.5 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger Collagen PF01391.18 GBG67344.1 - 0.045 13.5 2.8 0.061 13.1 2.8 1.1 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) NOA36 PF06524.12 GBG67344.1 - 3.7 6.8 5.7 4.1 6.6 5.7 1.0 1 0 0 1 1 1 0 NOA36 protein Osteopontin PF00865.18 GBG67344.1 - 5.1 6.5 7.7 5.5 6.4 7.7 1.1 1 0 0 1 1 1 0 Osteopontin Usp PF00582.26 GBG67345.1 - 0.0019 18.7 2.6 0.0029 18.1 2.6 1.3 1 0 0 1 1 1 1 Universal stress protein family Connexin PF00029.19 GBG67345.1 - 0.24 11.1 3.3 0.29 10.9 3.3 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 GBG67345.1 - 0.28 9.9 2.3 0.28 9.9 2.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4637 PF15470.6 GBG67345.1 - 0.48 10.1 8.7 0.58 9.9 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 GBG67345.1 - 1.4 7.1 9.8 1.5 7.0 9.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S10 PF00338.22 GBG67346.1 - 0.72 10.1 3.4 1.6 9.0 0.0 3.2 4 0 0 4 4 4 0 Ribosomal protein S10p/S20e RT_RNaseH_2 PF17919.1 GBG67347.1 - 2.3e-21 75.7 0.0 5.8e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67347.1 - 2.1e-20 72.9 0.0 5e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67347.1 - 9.6e-08 31.8 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG67347.1 - 2.6e-06 28.0 0.0 6.7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67347.1 - 4.3e-06 27.2 0.0 1.2e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG67347.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG67347.1 - 0.22 11.3 0.1 0.4 10.5 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease NIF PF03031.18 GBG67348.1 - 1.2e-22 80.3 0.0 1e-19 70.8 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase BRCT PF00533.26 GBG67348.1 - 6.6e-05 23.2 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GBG67348.1 - 0.0002 21.2 0.1 0.00051 19.9 0.0 1.7 2 0 0 2 2 2 1 twin BRCT domain NICE-1 PF15845.5 GBG67348.1 - 0.0081 16.9 0.4 0.0081 16.9 0.4 5.6 5 1 0 5 5 5 1 Cysteine-rich C-terminal 1 family CCDC53 PF10152.9 GBG67348.1 - 7.3 7.0 5.7 35 4.8 0.1 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RVT_1 PF00078.27 GBG67349.1 - 1.5e-37 129.3 0.0 7.7e-37 126.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4_2 PF13923.6 GBG67351.1 - 7.5e-07 28.9 3.4 7.5e-07 28.9 3.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG67351.1 - 2.6e-05 24.2 3.6 6.1e-05 23.0 3.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG67351.1 - 9.5e-05 22.2 2.6 9.5e-05 22.2 2.6 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 GBG67351.1 - 0.0001 22.3 10.2 0.043 13.7 1.0 3.2 1 1 2 3 3 3 3 Seven in absentia protein family zf-RING_2 PF13639.6 GBG67351.1 - 0.00011 22.4 3.1 0.00011 22.4 3.1 2.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GBG67351.1 - 0.00015 21.7 2.8 0.00064 19.6 2.8 2.1 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG67351.1 - 0.00078 19.3 2.9 0.00078 19.3 2.9 2.4 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-TRAF PF02176.18 GBG67351.1 - 0.0024 18.5 22.7 0.069 13.9 7.0 4.0 2 1 3 5 5 4 4 TRAF-type zinc finger zf-TRAF_2 PF15965.5 GBG67351.1 - 0.01 16.3 15.9 0.1 13.1 2.4 3.2 2 1 1 3 3 3 0 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 GBG67351.1 - 0.018 15.2 5.0 0.072 13.3 5.0 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TRAF_BIRC3_bd PF16673.5 GBG67351.1 - 0.049 13.4 1.1 0.14 12.0 1.1 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain ADIP PF11559.8 GBG67351.1 - 0.18 11.9 2.4 0.32 11.1 2.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-RING_11 PF17123.5 GBG67351.1 - 4.3 7.2 7.8 12 5.7 7.8 1.8 1 0 0 1 1 1 0 RING-like zinc finger Zn_Tnp_IS91 PF14319.6 GBG67351.1 - 4.4 7.4 13.3 4.7 7.3 0.6 2.8 2 0 0 2 2 2 0 Transposase zinc-binding domain Translin PF01997.16 GBG67352.1 - 2.9e-43 148.3 1.0 1.1e-25 90.9 0.0 2.8 2 0 0 2 2 2 2 Translin family RVT_1 PF00078.27 GBG67352.1 - 9.2e-25 87.5 0.0 1.6e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67352.1 - 2.9e-24 85.0 0.0 8.7e-24 83.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67352.1 - 2.5e-23 82.4 0.0 6.6e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67352.1 - 3.6e-18 65.4 0.2 9.1e-18 64.1 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG67352.1 - 2.9e-05 24.6 0.0 8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG67352.1 - 3.1e-05 24.2 0.2 0.00021 21.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG67352.1 - 3.2e-05 24.1 0.3 0.017 15.4 0.0 3.5 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG67352.1 - 0.00087 19.8 0.0 0.0034 17.9 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67352.1 - 0.0013 18.5 0.0 0.0039 17.0 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease PIF1 PF05970.14 GBG67352.1 - 0.0024 17.1 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Cytochrome_C7 PF14522.6 GBG67352.1 - 0.41 10.7 6.1 1.4 9.0 6.1 1.9 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Translin PF01997.16 GBG67353.1 - 2.1e-43 148.7 1.0 8.3e-26 91.2 0.0 2.8 2 0 0 2 2 2 2 Translin family RVT_1 PF00078.27 GBG67353.1 - 9.1e-25 87.5 0.0 1.6e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67353.1 - 3e-24 85.0 0.0 8.8e-24 83.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67353.1 - 2.5e-23 82.3 0.0 6.6e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67353.1 - 3.6e-18 65.4 0.2 9.1e-18 64.1 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG67353.1 - 2.9e-05 24.6 0.0 8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG67353.1 - 3.1e-05 24.2 0.2 0.00022 21.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG67353.1 - 3.2e-05 24.1 0.3 0.017 15.4 0.0 3.5 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG67353.1 - 0.00088 19.8 0.0 0.0035 17.9 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67353.1 - 0.0013 18.5 0.0 0.0039 17.0 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease PIF1 PF05970.14 GBG67353.1 - 0.0025 17.1 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Cytochrome_C7 PF14522.6 GBG67353.1 - 0.41 10.7 6.1 1.4 9.0 6.1 1.9 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c RT_RNaseH_2 PF17919.1 GBG67354.1 - 1.7e-31 108.2 0.1 5.3e-31 106.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67354.1 - 2.6e-31 108.9 0.1 4.6e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67354.1 - 9.2e-29 99.8 0.1 1.9e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG67354.1 - 0.0021 17.8 1.5 0.003 17.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) zf-CCHC_3 PF13917.6 GBG67354.1 - 7.1 6.7 6.3 0.59 10.1 1.2 1.9 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG67355.1 - 2.2e-26 92.7 0.1 3.6e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67355.1 - 9.6e-26 89.8 0.0 2.2e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67355.1 - 1.4e-23 83.2 0.0 2.9e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67355.1 - 8.1e-18 64.3 0.9 1.6e-17 63.3 0.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF4404 PF14357.6 GBG67356.1 - 0.081 13.6 1.2 0.081 13.6 1.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) WDCP PF15390.6 GBG67356.1 - 0.38 9.1 7.1 0.51 8.7 7.1 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family RD3 PF14473.6 GBG67356.1 - 0.61 9.9 7.2 0.32 10.8 4.2 1.9 1 1 1 2 2 2 0 RD3 protein Integrase_H2C2 PF17921.1 GBG67357.1 - 8.2e-11 41.9 0.0 2.1e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG67357.1 - 3.9e-08 33.5 0.0 3.5e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67357.1 - 2.7e-06 27.4 0.0 5.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67357.1 - 4.7e-06 26.8 0.0 1.6e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG67357.1 - 0.001 19.7 0.0 0.0028 18.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67357.1 - 0.0012 19.3 0.0 0.0031 18.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG67357.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG67357.1 - 0.05 13.9 0.1 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG67357.1 - 0.3 11.0 5.3 0.032 14.1 1.0 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG67357.1 - 0.48 10.6 1.5 1.1 9.5 1.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Alpha-amylase PF00128.24 GBG67358.1 - 7.8e-16 58.5 0.0 4.3e-10 39.7 0.0 3.2 2 1 1 3 3 3 3 Alpha amylase, catalytic domain CBM_48 PF02922.18 GBG67358.1 - 2.2e-14 53.6 0.0 5.8e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GST_N_2 PF13409.6 GBG67359.1 - 6.1e-17 61.7 0.0 1.8e-15 57.0 0.0 3.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GBG67359.1 - 3.5e-12 46.2 0.0 7.7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GBG67359.1 - 7e-08 32.6 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GBG67359.1 - 1.7e-05 24.9 0.0 3.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GBG67359.1 - 0.0042 17.5 0.0 1.9 8.9 0.0 2.7 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GBG67359.1 - 0.0079 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Amastin PF07344.11 GBG67361.1 - 0.013 15.4 5.0 0.016 15.1 5.0 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein LEA_2 PF03168.13 GBG67362.1 - 0.017 15.6 0.2 0.025 15.1 0.2 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein DDE_Tnp_4 PF13359.6 GBG67363.1 - 7e-19 68.0 0.0 1.7e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67363.1 - 2.8e-09 36.9 0.0 6.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein BicD PF09730.9 GBG67363.1 - 0.004 15.7 2.7 0.006 15.1 2.7 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Laminin_II PF06009.12 GBG67363.1 - 0.022 14.8 1.3 0.022 14.8 1.3 1.9 2 0 0 2 2 2 0 Laminin Domain II KELK PF15796.5 GBG67363.1 - 0.044 14.2 2.0 0.19 12.2 2.0 2.1 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CCDC106 PF15794.5 GBG67363.1 - 0.12 12.0 2.0 0.27 10.9 2.0 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 ADIP PF11559.8 GBG67363.1 - 0.32 11.1 7.1 0.063 13.4 2.3 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.13 GBG67363.1 - 0.53 10.4 3.7 0.91 9.6 0.8 2.1 2 0 0 2 2 2 0 DivIVA protein HALZ PF02183.18 GBG67363.1 - 0.88 9.8 5.1 2.4 8.5 0.5 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper GAS PF13851.6 GBG67363.1 - 0.96 8.8 7.3 0.47 9.8 2.4 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 GBG67363.1 - 1 9.5 4.0 16 5.7 0.2 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 GBG67363.1 - 1.6 8.8 11.2 0.39 10.8 3.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 GBG67363.1 - 5.2 7.6 8.0 24 5.4 3.9 2.4 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 GBG67363.1 - 6.3 7.0 5.7 7.5 6.7 0.6 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Myb_DNA-bind_4 PF13837.6 GBG67364.1 - 2.4e-11 43.9 4.8 4.1e-11 43.1 4.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67364.1 - 0.0019 18.5 1.4 0.0038 17.5 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG67364.1 - 0.0022 18.1 0.3 0.0051 17.0 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain RRM_1 PF00076.22 GBG67365.1 - 1.3e-18 66.6 0.2 4.2e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GBG67365.1 - 5.3e-09 35.7 0.0 6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RT_RNaseH PF17917.1 GBG67366.1 - 1.5e-24 86.3 0.1 2.9e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67366.1 - 1.9e-17 63.1 0.4 3.6e-17 62.2 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG67366.1 - 2.7e-17 62.7 0.0 6.2e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67366.1 - 1.6e-12 47.7 0.0 3.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG67366.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DUF465 PF04325.13 GBG67366.1 - 0.19 11.8 2.1 0.48 10.5 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Retrotrans_gag PF03732.17 GBG67368.1 - 0.0024 18.1 2.9 0.036 14.3 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG67368.1 - 0.0081 16.2 2.6 0.016 15.3 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Phage_lysozyme PF00959.19 GBG67368.1 - 0.016 15.6 0.2 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 Phage lysozyme CaM_binding PF07839.11 GBG67371.1 - 0.091 13.5 0.1 0.21 12.4 0.1 1.6 1 0 0 1 1 1 0 Plant calmodulin-binding domain REV PF00424.18 GBG67373.1 - 0.093 12.8 0.4 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) RE_AlwI PF09491.10 GBG67373.1 - 0.22 10.3 5.1 0.31 9.8 5.1 1.2 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF4407 PF14362.6 GBG67373.1 - 0.55 9.5 7.4 0.85 8.9 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3629 PF12302.8 GBG67373.1 - 1.1 8.7 5.9 1.9 7.9 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) PA26 PF04636.13 GBG67373.1 - 1.6 7.5 8.4 2.3 7.1 8.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 GBG67373.1 - 3.5 6.7 5.1 5.8 6.0 5.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Nbl1_Borealin_N PF10444.9 GBG67374.1 - 0.14 11.8 0.4 0.44 10.2 0.4 1.8 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Peptidase_M29 PF02073.15 GBG67376.1 - 0.0019 17.1 5.7 0.0028 16.5 5.7 1.2 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) DUF4722 PF15849.5 GBG67376.1 - 0.031 14.0 1.4 0.085 12.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4722) V-SNARE PF05008.15 GBG67376.1 - 0.045 14.1 0.6 0.12 12.7 0.6 1.8 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Baculo_PEP_C PF04513.12 GBG67376.1 - 0.079 13.0 1.5 0.22 11.5 1.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAM76 PF16046.5 GBG67376.1 - 0.21 10.9 6.7 0.3 10.4 6.7 1.2 1 0 0 1 1 1 0 FAM76 protein SlyX PF04102.12 GBG67376.1 - 0.25 12.0 16.8 1 10.0 0.7 4.0 4 0 0 4 4 4 0 SlyX CLZ PF16526.5 GBG67376.1 - 0.61 10.5 3.6 9.5 6.7 0.2 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-CCHC PF00098.23 GBG67377.1 - 6.1e-06 26.1 3.5 1.2e-05 25.1 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG67377.1 - 0.066 12.9 1.0 0.15 11.8 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG67377.1 - 0.067 13.2 1.0 0.2 11.6 0.9 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG67378.1 - 0.00011 22.0 1.5 0.00011 22.0 1.5 2.2 2 0 0 2 2 2 1 Zinc knuckle SAP PF02037.27 GBG67378.1 - 0.026 14.3 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 SAP domain zf-CCHC_2 PF13696.6 GBG67378.1 - 7.2 6.5 8.1 1.6 8.7 2.3 2.3 2 0 0 2 2 2 0 Zinc knuckle CDC45 PF02724.14 GBG67379.1 - 0.04 12.2 12.8 0.055 11.8 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Afi1 PF07792.12 GBG67379.1 - 0.091 13.2 6.6 0.16 12.5 6.6 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop14 PF04147.12 GBG67379.1 - 0.15 10.2 20.3 0.21 9.8 20.3 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 GBG67379.1 - 1.9 8.5 14.4 4.4 7.3 14.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 GBG67379.1 - 4.8 5.2 37.3 6.6 4.7 37.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi GTP1_OBG PF01018.22 GBG67380.1 - 0.1 12.2 3.0 1.7 8.2 1.1 2.6 3 0 0 3 3 3 0 GTP1/OBG SGL PF08450.12 GBG67382.1 - 0.034 13.7 0.0 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region RVT_1 PF00078.27 GBG67383.1 - 7.2e-29 100.9 0.4 1.8e-28 99.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67383.1 - 9.9e-22 77.2 0.0 1.8e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67383.1 - 3e-20 72.1 0.0 5.3e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67383.1 - 7.4e-19 67.6 0.2 1.5e-18 66.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG67383.1 - 3.8e-07 29.9 0.0 8.1e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67383.1 - 3.8e-06 27.4 0.0 7.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67383.1 - 0.00078 20.0 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG67383.1 - 0.0025 18.1 0.1 0.0096 16.2 0.1 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG67383.1 - 0.0078 16.4 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Pkinase_Tyr PF07714.17 GBG67384.1 - 1.9e-24 86.3 0.0 6.9e-19 68.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG67384.1 - 8.8e-23 81.0 0.0 1.2e-15 57.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain FixQ PF05545.11 GBG67384.1 - 0.056 13.4 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ GRP PF07172.11 GBG67386.1 - 9.4 7.0 39.6 1.2 9.9 3.5 2.2 2 0 0 2 2 2 0 Glycine rich protein family Efg1 PF10153.9 GBG67388.1 - 1e-22 80.6 8.5 1e-22 80.6 8.5 1.8 2 0 0 2 2 2 1 rRNA-processing protein Efg1 Nup88 PF10168.9 GBG67388.1 - 0.13 10.0 5.5 0.17 9.7 5.5 1.1 1 0 0 1 1 1 0 Nuclear pore component TetR_C_24 PF17932.1 GBG67388.1 - 0.79 10.0 7.2 6.6 7.0 0.1 2.5 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FAM76 PF16046.5 GBG67388.1 - 3.2 7.0 11.5 1.3 8.3 8.1 1.8 2 0 0 2 2 2 0 FAM76 protein DUF659 PF04937.15 GBG67389.1 - 1.4e-39 135.4 0.1 3.6e-39 134.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG67389.1 - 0.091 12.6 0.0 0.091 12.6 0.0 2.0 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region PAP1 PF08601.10 GBG67389.1 - 5.2 6.7 20.2 9.5 5.8 20.2 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SAP PF02037.27 GBG67391.1 - 0.047 13.5 0.1 0.047 13.5 0.1 1.7 2 0 0 2 2 2 0 SAP domain FtsK_SpoIIIE PF01580.18 GBG67393.1 - 0.018 14.4 0.3 0.027 13.9 0.3 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family FeThRed_A PF02941.15 GBG67393.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase variable alpha chain DUF2967 PF11179.8 GBG67393.1 - 2.7 6.0 5.3 3.8 5.5 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) GRP PF07172.11 GBG67393.1 - 3.1 8.6 27.8 0.31 11.8 23.2 1.8 2 0 0 2 2 2 0 Glycine rich protein family Pkinase_Tyr PF07714.17 GBG67395.1 - 3.6e-44 151.0 0.0 2.7e-22 79.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG67395.1 - 7.9e-32 110.6 0.0 1.4e-16 60.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 GBG67395.1 - 0.021 14.2 0.2 0.67 9.3 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DAG1 PF05454.11 GBG67395.1 - 0.036 13.5 0.0 8.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) MLANA PF14991.6 GBG67395.1 - 0.12 12.6 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein melan-A Peptidase_C48 PF02902.19 GBG67399.1 - 4.3e-22 79.0 0.0 1.1e-21 77.7 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.19 GBG67400.1 - 2e-22 80.1 0.0 4.9e-22 78.8 0.0 1.6 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain CDC45 PF02724.14 GBG67401.1 - 1.3 7.2 14.7 1.5 7.0 14.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Herpes_UL56 PF04534.12 GBG67401.1 - 9.1 5.7 9.0 11 5.5 9.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein Tetraspanin PF00335.20 GBG67402.1 - 1.2e-05 25.2 6.7 1.2e-05 25.2 6.7 2.1 1 1 1 2 2 2 1 Tetraspanin family Phage_holin_3_6 PF07332.11 GBG67402.1 - 0.11 12.6 0.3 0.32 11.0 0.1 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III peroxidase PF00141.23 GBG67404.1 - 1.6e-30 106.5 0.0 9.1e-24 84.4 0.0 2.2 1 1 1 2 2 2 2 Peroxidase Peptidase_C12 PF01088.21 GBG67405.1 - 2.7e-68 229.9 0.0 2.7e-68 229.9 0.0 3.2 3 1 1 4 4 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 GBG67405.1 - 8e-17 60.9 0.1 8e-17 60.9 0.1 3.7 4 0 0 4 4 2 1 Ubiquitin carboxyl-terminal hydrolases Nop14 PF04147.12 GBG67405.1 - 3.6e-05 22.2 15.2 5.1e-05 21.7 15.2 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 GBG67405.1 - 0.0002 19.8 23.6 0.00027 19.4 23.6 1.2 1 0 0 1 1 1 1 CDC45-like protein SRP-alpha_N PF04086.13 GBG67405.1 - 0.0025 17.8 19.6 0.0038 17.2 19.6 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal RMP PF14996.6 GBG67405.1 - 0.02 15.1 5.0 0.02 15.1 5.0 2.4 1 1 1 2 2 2 0 Retinal Maintenance Presenilin PF01080.17 GBG67405.1 - 0.052 12.3 12.3 0.076 11.8 12.3 1.2 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 GBG67405.1 - 0.066 12.7 16.7 0.15 11.5 16.7 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.12 GBG67405.1 - 0.072 12.9 21.4 0.12 12.2 21.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GPCR_chapero_1 PF11904.8 GBG67405.1 - 0.075 12.5 12.9 0.12 11.8 12.9 1.2 1 0 0 1 1 1 0 GPCR-chaperone FAM220 PF15487.6 GBG67405.1 - 0.1 12.2 10.3 0.18 11.4 10.3 1.3 1 0 0 1 1 1 0 FAM220 family BSP_II PF05432.11 GBG67405.1 - 0.18 11.5 17.6 0.38 10.4 17.6 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) LAP1C PF05609.12 GBG67405.1 - 0.19 10.8 10.5 0.31 10.1 10.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) OAD_gamma PF04277.13 GBG67405.1 - 0.23 12.1 6.3 0.63 10.7 0.6 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4604 PF15377.6 GBG67405.1 - 0.23 11.9 36.8 0.45 10.9 36.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CAC1F_C PF16885.5 GBG67405.1 - 0.37 10.4 9.5 0.65 9.6 9.5 1.3 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF4569 PF15133.6 GBG67405.1 - 2.2 7.9 12.1 4.4 6.9 12.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Merozoite_SPAM PF07133.11 GBG67405.1 - 2.7 7.9 28.8 0.057 13.4 21.8 1.8 2 0 0 2 2 1 0 Merozoite surface protein (SPAM) SAPS PF04499.15 GBG67405.1 - 4.2 6.0 11.4 6.2 5.5 11.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MDFI PF15316.6 GBG67405.1 - 5.2 7.1 10.7 12 5.9 10.7 1.5 1 0 0 1 1 1 0 MyoD family inhibitor GREB1 PF15782.5 GBG67405.1 - 8.2 3.4 7.1 11 2.9 7.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RNA_pol_3_Rpc31 PF11705.8 GBG67407.1 - 4.4 7.5 15.0 8.8 6.5 15.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RT_RNaseH_2 PF17919.1 GBG67408.1 - 1.7e-28 98.6 0.0 4.1e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67408.1 - 4.3e-24 84.8 0.0 1.1e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67408.1 - 2.7e-17 63.0 0.0 4.8e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG67408.1 - 6.9e-08 32.9 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67408.1 - 4e-07 30.6 0.0 8.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG67408.1 - 8.8e-07 28.8 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67408.1 - 0.00027 20.7 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG67408.1 - 0.00065 19.6 0.1 0.0025 17.7 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG67408.1 - 0.0026 18.0 0.0 0.0084 16.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG67408.1 - 0.012 15.9 0.2 0.058 13.7 0.2 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein Cullin PF00888.22 GBG67409.1 - 2.3e-14 53.0 0.0 7.7e-14 51.2 0.0 1.8 1 1 0 1 1 1 1 Cullin family C_GCAxxG_C_C PF09719.10 GBG67409.1 - 0.022 15.1 1.5 0.052 13.8 1.5 1.7 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Rrf2 PF02082.20 GBG67409.1 - 0.092 13.1 0.1 2.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Transcriptional regulator Choline_transpo PF04515.12 GBG67410.1 - 1.1e-46 159.5 30.7 4.2e-45 154.4 18.9 3.6 2 2 1 3 3 3 3 Plasma-membrane choline transporter CPP1-like PF11833.8 GBG67410.1 - 6.6 6.3 14.2 0.055 13.1 1.0 2.7 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MutS_V PF00488.21 GBG67411.1 - 2.4e-65 220.1 0.3 5.1e-65 219.0 0.3 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GBG67411.1 - 7e-22 78.6 0.7 1.6e-21 77.4 0.1 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 GBG67411.1 - 3.8e-08 33.6 0.0 8.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_16 PF13191.6 GBG67411.1 - 0.019 15.3 0.1 0.16 12.3 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.6 GBG67411.1 - 0.04 13.7 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GBG67411.1 - 0.043 14.3 0.8 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 GBG67411.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GBG67411.1 - 0.062 13.6 0.0 0.74 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GBG67411.1 - 0.07 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GBG67411.1 - 0.11 13.0 0.8 0.29 11.6 0.1 2.1 2 0 0 2 2 2 0 ABC transporter RVT_1 PF00078.27 GBG67412.1 - 5.9e-22 78.3 0.1 1.1e-21 77.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67412.1 - 8.1e-13 48.3 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67412.1 - 0.0001 22.6 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Apt1 PF10351.9 GBG67412.1 - 5.6 5.7 7.3 12 4.6 7.3 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain RVT_1 PF00078.27 GBG67413.1 - 1.4e-32 113.0 0.1 2.2e-32 112.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67413.1 - 6.8e-30 103.1 0.0 2.1e-29 101.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67413.1 - 2.6e-27 95.1 0.0 6.1e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4685 PF15737.5 GBG67415.1 - 0.31 11.5 2.9 0.45 11.0 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) N6-adenineMlase PF10237.9 GBG67416.1 - 4.5e-48 163.1 0.3 6.6e-48 162.5 0.3 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Rotamase PF00639.21 GBG67417.1 - 1.9e-21 76.8 0.0 2.3e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GBG67417.1 - 1.2e-18 67.7 0.0 1.5e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GBG67417.1 - 0.0085 16.9 0.0 0.01 16.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 GBG67417.1 - 0.15 12.7 0.0 0.24 12.1 0.0 1.3 1 0 0 1 1 1 0 X8 domain SR-25 PF10500.9 GBG67419.1 - 9.1e-07 28.7 19.3 1.2e-06 28.3 19.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2207 PF09972.9 GBG67419.1 - 0.00063 18.6 0.0 0.028 13.2 0.0 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) Neur_chan_memb PF02932.16 GBG67419.1 - 0.0011 19.0 0.2 0.0011 19.0 0.2 1.6 2 0 0 2 2 1 1 Neurotransmitter-gated ion-channel transmembrane region Shisa PF13908.6 GBG67419.1 - 0.0035 17.6 0.1 0.0035 17.6 0.1 1.9 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 GBG67419.1 - 0.0061 17.5 4.7 0.0068 17.3 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4834) Chorion_2 PF03964.15 GBG67419.1 - 0.031 15.1 10.9 0.06 14.2 10.9 1.5 1 0 0 1 1 1 0 Chorion family 2 Cadherin_C_2 PF16492.5 GBG67419.1 - 0.067 13.9 0.1 0.067 13.9 0.1 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal SRP-alpha_N PF04086.13 GBG67419.1 - 0.082 12.8 4.8 0.096 12.6 4.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-dskA_traR PF01258.17 GBG67419.1 - 0.19 11.7 1.0 0.41 10.6 1.0 1.6 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger Miga PF10265.9 GBG67419.1 - 0.24 10.3 1.3 0.28 10.1 1.3 1.1 1 0 0 1 1 1 0 Mitoguardin Pex24p PF06398.11 GBG67419.1 - 0.33 9.9 0.0 0.33 9.9 0.0 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF4692 PF15763.5 GBG67419.1 - 0.54 10.7 9.5 1.2 9.5 9.3 1.7 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Macoilin PF09726.9 GBG67419.1 - 0.59 8.6 9.4 0.86 8.1 9.4 1.2 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 GBG67419.1 - 0.74 9.5 13.3 0.99 9.1 13.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SPX PF03105.19 GBG67419.1 - 1.1 9.1 17.6 1.5 8.7 17.6 1.0 1 0 0 1 1 1 0 SPX domain Phage_holin_3_6 PF07332.11 GBG67419.1 - 1.6 8.8 7.9 5.3 7.1 2.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III QWRF PF04484.12 GBG67419.1 - 2.6 7.7 10.1 3 7.5 10.1 1.1 1 0 0 1 1 1 0 QWRF family FAM199X PF15814.5 GBG67419.1 - 2.8 6.9 13.7 3.6 6.5 13.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X Menin PF05053.13 GBG67419.1 - 3.6 5.8 4.5 4.6 5.5 4.5 1.1 1 0 0 1 1 1 0 Menin DUF4614 PF15391.6 GBG67419.1 - 4.4 7.2 14.6 6.3 6.7 14.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Halogen_Hydrol PF10112.9 GBG67419.1 - 5.6 6.9 5.6 3.3 7.7 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Pkinase PF00069.25 GBG67420.1 - 3e-28 98.9 0.0 5.6e-22 78.4 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG67420.1 - 1.5e-27 96.6 0.0 6.4e-20 71.5 0.0 2.5 1 1 0 2 2 2 2 Protein tyrosine kinase zf-CCHC PF00098.23 GBG67420.1 - 1.4e-06 28.1 2.2 3.5e-06 26.8 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle GIY-YIG PF01541.24 GBG67420.1 - 1.1e-05 25.6 0.3 0.00016 21.9 0.0 2.7 2 0 0 2 2 2 1 GIY-YIG catalytic domain Alanine_zipper PF11839.8 GBG67420.1 - 0.019 15.3 19.8 0.061 13.7 19.8 1.8 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein APH PF01636.23 GBG67420.1 - 0.087 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family rpo132 PF12415.8 GBG67420.1 - 0.088 12.1 0.0 0.57 9.5 0.0 2.1 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase zf-CCHC_2 PF13696.6 GBG67420.1 - 0.16 11.8 2.6 0.44 10.4 2.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Prok-RING_1 PF14446.6 GBG67420.1 - 1.4 8.9 3.7 0.53 10.3 0.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Retrotrans_gag PF03732.17 GBG67421.1 - 0.0011 19.2 0.9 0.0038 17.5 0.0 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein FAT PF02259.23 GBG67421.1 - 0.0056 15.9 0.0 0.0088 15.3 0.0 1.3 1 0 0 1 1 1 1 FAT domain RVP_2 PF08284.11 GBG67422.1 - 1.2e-06 28.3 2.8 1.7e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67422.1 - 3.8e-06 27.5 0.0 3.8e-06 27.5 0.0 2.6 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67422.1 - 0.00038 21.0 0.1 0.00038 21.0 0.1 2.4 2 2 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG67422.1 - 0.0011 18.8 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 Putative peptidase (DUF1758) LRR_8 PF13855.6 GBG67422.1 - 0.0045 16.7 6.4 0.0085 15.8 3.0 2.9 2 1 1 3 3 3 1 Leucine rich repeat Asp_protease PF09668.10 GBG67422.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease LRR_1 PF00560.33 GBG67422.1 - 0.22 12.2 0.2 0.22 12.2 0.2 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 GBG67422.1 - 0.74 10.3 8.4 0.19 12.2 2.6 2.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) RT_RNaseH PF17917.1 GBG67423.1 - 5.9e-24 84.4 0.0 1.9e-23 82.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67423.1 - 1.2e-22 79.8 0.0 3.3e-22 78.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67423.1 - 1.3e-13 50.8 0.0 4.2e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67423.1 - 1.6e-10 40.9 0.8 1.1e-09 38.1 0.0 2.5 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67423.1 - 1.9e-09 37.8 0.0 5.7e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG67423.1 - 7.9e-07 28.9 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67423.1 - 6e-06 26.8 0.0 1.7e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67423.1 - 0.0022 18.5 0.0 0.0051 17.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Exo_endo_phos_2 PF14529.6 GBG67424.1 - 0.18 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase TT_ORF1 PF02956.14 GBG67424.1 - 3 6.4 6.1 5.3 5.6 6.1 1.3 1 0 0 1 1 1 0 TT viral orf 1 RT_RNaseH_2 PF17919.1 GBG67425.1 - 4.1e-30 103.8 0.0 7.2e-29 99.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67425.1 - 2.4e-28 98.5 0.1 8.4e-27 93.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67425.1 - 2.5e-19 69.1 0.3 2.5e-19 69.1 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG67425.1 - 3.2e-14 53.1 0.0 7.7e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG67425.1 - 8.4e-14 51.6 0.0 1.7e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG67425.1 - 0.0005 20.2 0.1 0.0014 18.8 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger CortBP2 PF09727.9 GBG67425.1 - 0.091 12.7 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Cortactin-binding protein-2 LcrG PF07216.12 GBG67425.1 - 0.19 11.7 1.2 0.48 10.4 1.2 1.6 1 0 0 1 1 1 0 LcrG protein LRR_4 PF12799.7 GBG67426.1 - 5.4e-07 29.8 8.4 6e-05 23.3 1.5 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GBG67426.1 - 3.1e-06 27.4 6.4 3.1e-06 27.4 6.4 1.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GBG67426.1 - 3.7e-05 23.7 0.6 0.56 11.0 0.0 3.1 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_8 PF13855.6 GBG67426.1 - 0.0001 22.0 1.2 0.0003 20.5 0.9 1.7 1 1 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 GBG67426.1 - 0.00029 20.6 1.6 0.17 12.0 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeat Peptidase_C101 PF16218.5 GBG67426.1 - 0.15 11.3 0.0 0.18 11.0 0.0 1.0 1 0 0 1 1 1 0 Peptidase family C101 Peptidase_S10 PF00450.22 GBG67427.1 - 8.1e-94 315.4 0.0 1.9e-93 314.1 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase TSC22 PF01166.18 GBG67428.1 - 0.0046 17.2 0.1 0.0089 16.3 0.1 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family Orn_Arg_deC_N PF02784.16 GBG67428.1 - 0.05 13.0 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain SlyX PF04102.12 GBG67428.1 - 0.064 13.9 0.0 1.3 9.7 0.0 2.3 2 0 0 2 2 2 0 SlyX FAM76 PF16046.5 GBG67428.1 - 1 8.7 5.1 1.7 8.0 5.1 1.6 1 1 0 1 1 1 0 FAM76 protein Cofilin_ADF PF00241.20 GBG67429.1 - 7.6e-35 119.4 0.0 8.6e-35 119.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ORC3_N PF07034.11 GBG67430.1 - 3.8 6.5 8.2 1.5 7.8 5.2 1.9 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus Draxin PF15550.6 GBG67431.1 - 4.6 7.0 7.5 2.7 7.8 0.1 2.5 2 0 0 2 2 2 0 Draxin Peptidase_C97 PF05903.14 GBG67432.1 - 1.6e-43 148.2 0.0 2.1e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain PSI_PsaF PF02507.15 GBG67433.1 - 6.7e-79 263.7 0.0 1.2e-78 262.8 0.0 1.4 1 0 0 1 1 1 1 Photosystem I reaction centre subunit III UPF0047 PF01894.17 GBG67435.1 - 2e-14 53.7 0.0 2.5e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 X PF00739.19 GBG67436.1 - 1.3e-05 25.3 0.8 0.23 11.6 0.1 2.5 2 0 0 2 2 2 2 Trans-activation protein X F-box-like PF12937.7 GBG67436.1 - 0.00067 19.5 0.4 0.0035 17.2 0.4 2.3 1 0 0 1 1 1 1 F-box-like DUF5066 PF16728.5 GBG67436.1 - 0.0017 17.7 1.5 1.6 8.0 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5066) Alpha-amylase_C PF02806.18 GBG67436.1 - 0.006 17.0 0.4 7.3 7.1 0.1 2.7 2 0 0 2 2 2 2 Alpha amylase, C-terminal all-beta domain Pentapeptide PF00805.22 GBG67436.1 - 0.016 14.8 13.1 0.58 9.9 2.8 2.4 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) F-box PF00646.33 GBG67436.1 - 0.019 14.8 0.4 0.019 14.8 0.4 3.4 3 0 0 3 3 3 0 F-box domain UPF0172 PF03665.13 GBG67436.1 - 0.15 12.1 0.0 30 4.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DUF3528 PF12045.8 GBG67436.1 - 0.16 12.5 0.0 39 4.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3528) Drc1-Sld2 PF11719.8 GBG67436.1 - 0.25 10.9 3.5 0.55 9.7 3.5 1.5 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF1645 PF07816.11 GBG67436.1 - 0.69 10.5 4.6 1.4 9.5 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF1010 PF06231.11 GBG67436.1 - 8.7 6.9 6.2 45 4.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) Pkinase PF00069.25 GBG67438.1 - 1.8e-43 148.8 0.0 2.6e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG67438.1 - 3.6e-42 144.4 0.0 5.4e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 GBG67438.1 - 1.2e-24 85.9 28.2 6.7e-10 38.6 4.4 5.4 3 3 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 GBG67438.1 - 6.3e-16 58.2 32.4 0.00068 20.0 1.6 7.5 3 3 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG67438.1 - 8e-11 40.9 31.3 2.8 8.8 0.3 11.5 12 0 0 12 12 12 4 Leucine Rich Repeat LRRNT_2 PF08263.12 GBG67438.1 - 0.00041 20.6 2.0 0.00089 19.5 2.0 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 GBG67438.1 - 0.009 16.0 24.6 6.6 7.1 0.3 9.1 9 0 0 9 9 9 2 Leucine Rich repeat TMEM154 PF15102.6 GBG67438.1 - 0.16 11.9 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family TolA_bind_tri PF16331.5 GBG67439.1 - 0.1 12.7 0.6 0.95 9.6 0.0 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF1192 PF06698.11 GBG67439.1 - 0.19 11.8 0.0 1.7 8.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF459 PF04311.13 GBG67439.1 - 0.39 9.7 4.5 0.6 9.0 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) adh_short_C2 PF13561.6 GBG67440.1 - 2.5e-57 194.1 0.0 2.3e-55 187.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GBG67440.1 - 6.9e-45 152.9 1.1 6.1e-43 146.5 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GBG67440.1 - 1.5e-06 28.3 0.0 3.1e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 GBG67440.1 - 0.02 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 GBG67440.1 - 0.12 11.8 0.1 0.27 10.7 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_M20 PF01546.28 GBG67441.1 - 3.6e-27 95.4 0.0 1.4e-13 51.1 0.0 2.6 2 1 0 2 2 2 2 Peptidase family M20/M25/M40 RT_RNaseH_2 PF17919.1 GBG67442.1 - 2e-31 108.0 0.0 4.4e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67442.1 - 8.9e-29 99.9 0.1 2.4e-28 98.5 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67442.1 - 2e-20 72.7 0.1 3.8e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67442.1 - 3.8e-12 46.2 0.1 7.3e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG67442.1 - 0.0004 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG67442.1 - 0.015 15.5 2.6 0.049 13.9 0.0 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein rve PF00665.26 GBG67442.1 - 0.055 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain DUF5401 PF17380.2 GBG67442.1 - 4.5 5.2 6.5 7 4.6 6.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RT_RNaseH_2 PF17919.1 GBG67443.1 - 3.8e-34 116.7 0.0 6.8e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67443.1 - 6.7e-32 110.8 0.1 1.2e-31 110.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67443.1 - 5.1e-31 107.1 0.0 9.2e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG67443.1 - 2.5e-07 31.2 0.0 6.6e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67443.1 - 6.5e-05 23.5 0.0 0.00015 22.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG67443.1 - 0.00018 21.3 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG67443.1 - 0.0004 20.2 0.0 0.0011 18.8 0.0 1.6 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG67443.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG67444.1 - 1.6e-30 106.3 0.0 2.7e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG67444.1 - 0.0027 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG67444.1 - 0.014 16.0 0.0 0.07 13.7 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG67444.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) ZapB PF06005.12 GBG67446.1 - 0.0053 17.2 0.0 0.015 15.8 0.0 1.7 1 1 0 1 1 1 1 Cell division protein ZapB VBS PF08913.10 GBG67446.1 - 0.018 15.5 2.0 0.027 14.9 2.0 1.3 1 1 0 1 1 1 0 Vinculin Binding Site ABC_tran_CTD PF16326.5 GBG67446.1 - 0.051 13.8 1.2 0.87 9.9 1.8 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 GBG67446.1 - 0.13 12.7 3.2 0.58 10.7 0.8 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein RT_RNaseH_2 PF17919.1 GBG67447.1 - 2.8e-47 158.8 0.0 6e-26 90.4 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67447.1 - 1.6e-40 139.0 1.3 7.4e-29 100.8 0.1 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67447.1 - 8.9e-33 112.7 0.0 2.5e-21 75.9 0.0 3.1 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG67447.1 - 4e-12 46.5 0.0 3.2e-07 30.8 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67447.1 - 2.4e-11 44.1 0.0 1.8e-06 28.5 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG67447.1 - 3.3e-08 33.4 0.0 4.7e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67447.1 - 8.9e-07 28.7 0.0 0.0024 17.6 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.20 GBG67447.1 - 0.027 14.8 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG67447.1 - 0.21 11.9 2.5 4.7 7.6 0.1 3.8 3 0 0 3 3 3 0 Retrotransposon gag protein GRP PF07172.11 GBG67447.1 - 3.7 8.3 26.3 10 6.9 26.3 1.7 1 0 0 1 1 1 0 Glycine rich protein family DUF4309 PF14172.6 GBG67448.1 - 0.14 12.2 0.1 0.21 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) Myb_DNA-bind_4 PF13837.6 GBG67449.1 - 3e-10 40.3 2.5 5.9e-10 39.4 2.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67449.1 - 0.014 15.7 1.0 0.036 14.4 1.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1491 PF07372.12 GBG67449.1 - 0.022 15.1 0.3 0.065 13.6 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) Myb_DNA-bind_5 PF13873.6 GBG67449.1 - 0.095 12.8 3.0 0.2 11.7 3.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TRAP_alpha PF03896.16 GBG67450.1 - 0.0043 16.3 0.8 0.0047 16.2 0.8 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 GBG67450.1 - 0.0052 15.0 6.1 0.0052 15.0 6.1 1.0 1 0 0 1 1 1 1 DNA polymerase phi Tankyrase_bdg_C PF15327.6 GBG67450.1 - 0.015 15.7 0.4 0.018 15.5 0.4 1.2 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain SDA1 PF05285.12 GBG67450.1 - 0.023 14.1 5.6 0.022 14.2 5.6 1.1 1 0 0 1 1 1 0 SDA1 PBP1_TM PF14812.6 GBG67450.1 - 0.031 14.7 1.1 0.048 14.0 1.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 GBG67450.1 - 0.031 14.7 5.9 0.046 14.1 5.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 GBG67450.1 - 0.046 13.4 6.3 0.06 13.0 6.3 1.2 1 0 0 1 1 1 0 FAM176 family PI3K_1B_p101 PF10486.9 GBG67450.1 - 0.08 10.7 1.1 0.083 10.7 1.1 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Connexin PF00029.19 GBG67450.1 - 0.14 11.9 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Connexin G0-G1_switch_2 PF15103.6 GBG67450.1 - 0.33 11.4 2.9 0.44 11.0 2.9 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 CDC45 PF02724.14 GBG67450.1 - 0.4 8.9 7.6 0.47 8.7 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 GBG67450.1 - 0.5 10.1 12.0 0.66 9.7 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RPN2_C PF18004.1 GBG67450.1 - 0.67 9.9 6.9 0.78 9.7 6.9 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain HSP90 PF00183.18 GBG67450.1 - 1.7 7.4 10.6 2.1 7.1 10.6 1.0 1 0 0 1 1 1 0 Hsp90 protein Nop14 PF04147.12 GBG67450.1 - 5.5 5.1 13.8 6.4 4.9 13.8 1.0 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 GBG67450.1 - 6.1 6.6 10.3 7.5 6.3 10.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.13 GBG67450.1 - 6.2 5.7 16.4 8 5.3 16.4 1.1 1 0 0 1 1 1 0 Paf1 Sporozoite_P67 PF05642.11 GBG67450.1 - 6.5 4.7 5.6 7.3 4.5 5.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cnd2 PF05786.14 GBG67450.1 - 8.8 4.8 8.8 11 4.5 8.8 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Pkinase PF00069.25 GBG67451.1 - 5.4e-36 124.3 0.0 1e-35 123.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG67451.1 - 1.8e-31 109.4 0.0 1.4e-30 106.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_S78_2 PF14550.6 GBG67452.1 - 0.037 14.1 2.0 0.11 12.7 0.1 2.3 3 0 0 3 3 3 0 Putative phage serine protease XkdF Myb_DNA-bind_4 PF13837.6 GBG67453.1 - 2.8e-07 30.8 3.7 6.6e-07 29.6 3.7 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG67453.1 - 0.0045 17.2 0.2 0.12 12.6 0.9 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67453.1 - 0.0074 16.6 0.9 0.023 15.0 0.9 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG67453.1 - 0.074 13.1 1.5 0.16 12.1 1.5 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG67454.1 - 2.2e-20 72.9 0.2 1.1e-19 70.6 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67454.1 - 6.6e-11 42.2 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG67454.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Transposase DDE domain Topo_Zn_Ribbon PF08272.11 GBG67455.1 - 0.55 9.9 2.4 0.39 10.4 0.2 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Ribosomal_60s PF00428.19 GBG67457.1 - 0.012 16.2 5.7 0.012 16.2 5.7 6.4 7 0 0 7 7 7 0 60s Acidic ribosomal protein DUF5473 PF17567.2 GBG67457.1 - 0.036 14.3 0.1 0.036 14.3 0.1 2.2 2 1 1 3 3 3 0 Family of unknown function (DUF5473) SVA PF05326.11 GBG67457.1 - 0.11 12.5 3.4 0.27 11.2 3.4 1.6 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) F-box-like PF12937.7 GBG67458.1 - 1.9e-06 27.7 0.1 3.4e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG67458.1 - 3.2e-05 23.7 0.1 0.0013 18.5 0.1 2.5 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 GBG67458.1 - 0.0013 19.0 0.2 0.43 11.1 0.0 3.4 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) NOA36 PF06524.12 GBG67458.1 - 0.004 16.5 30.0 0.0062 15.9 30.0 1.2 1 0 0 1 1 1 1 NOA36 protein DUF913 PF06025.12 GBG67458.1 - 0.01 14.8 0.4 0.013 14.5 0.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LRR_6 PF13516.6 GBG67458.1 - 0.064 13.3 0.0 2.7 8.3 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat BUD22 PF09073.10 GBG67458.1 - 0.16 11.3 21.8 0.2 10.9 21.8 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG67458.1 - 2 6.5 33.1 2.6 6.1 33.1 1.0 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG67458.1 - 2.7 6.7 10.4 2.9 6.6 9.3 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Gp_dh_C PF02800.20 GBG67459.1 - 1.1e-52 177.8 0.0 1.9e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG67459.1 - 1.8e-37 127.7 0.0 3.6e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GBG67459.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG67459.1 - 0.008 16.3 0.6 0.035 14.2 0.6 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 GBG67459.1 - 0.031 14.3 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NicO PF03824.16 GBG67460.1 - 0.0053 16.1 6.2 0.011 15.0 6.2 1.5 1 0 0 1 1 1 1 High-affinity nickel-transport protein SPX PF03105.19 GBG67460.1 - 8.1 6.2 21.4 1.5 8.7 4.9 2.1 2 0 0 2 2 2 0 SPX domain DUF563 PF04577.14 GBG67462.1 - 4e-13 50.0 0.4 3.3e-10 40.5 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF563) DUF3340 PF11818.8 GBG67462.1 - 0.02 15.1 0.3 0.02 15.1 0.3 2.4 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Menin PF05053.13 GBG67462.1 - 0.27 9.5 3.2 0.46 8.8 3.2 1.4 1 0 0 1 1 1 0 Menin TRAP_alpha PF03896.16 GBG67462.1 - 0.51 9.5 1.6 1.1 8.4 1.6 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 GBG67462.1 - 1.6 8.0 8.4 0.26 10.5 4.1 1.8 2 0 0 2 2 2 0 NOA36 protein DNA_pol_phi PF04931.13 GBG67462.1 - 8.1 4.4 10.4 0.23 9.5 4.0 1.5 2 0 0 2 2 2 0 DNA polymerase phi DUF3797 PF12677.7 GBG67463.1 - 0.036 13.9 2.1 12 5.9 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) Dimer_Tnp_hAT PF05699.14 GBG67464.1 - 3e-06 26.9 0.2 5e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DnaJ_C PF01556.18 GBG67465.1 - 2.8e-38 131.3 0.0 3.7e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GBG67465.1 - 1e-25 89.6 0.7 1.5e-25 89.0 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GBG67465.1 - 8.7e-12 45.2 18.2 8.7e-12 45.2 18.2 2.4 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 GBG67465.1 - 0.025 14.5 18.3 0.61 10.1 6.2 3.5 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein HNH_5 PF14279.6 GBG67468.1 - 4.4e-16 58.5 0.2 4.4e-16 58.5 0.2 1.9 3 0 0 3 3 3 1 HNH endonuclease HNH PF01844.23 GBG67468.1 - 3.3e-12 46.4 0.3 8.1e-12 45.1 0.3 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 GBG67468.1 - 1.4e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 GBG67469.1 - 3.8e-16 58.7 0.2 3.8e-16 58.7 0.2 2.0 3 0 0 3 3 3 1 HNH endonuclease HNH PF01844.23 GBG67469.1 - 2.7e-12 46.7 0.3 7e-12 45.3 0.3 1.8 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 GBG67469.1 - 1.2e-06 28.3 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Methyltransf_31 PF13847.6 GBG67470.1 - 1.8e-13 50.5 0.0 2.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG67470.1 - 7.3e-10 39.4 0.0 1.3e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG67470.1 - 8.6e-07 29.6 0.0 1.8e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG67470.1 - 6.6e-06 26.0 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG67470.1 - 6.7e-06 26.8 0.0 1.7e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 GBG67470.1 - 7e-05 22.8 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 GBG67470.1 - 0.0016 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RVT_1 PF00078.27 GBG67471.1 - 1.3e-24 86.9 0.0 1.8e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG67473.1 - 0.00029 20.8 0.8 0.00046 20.1 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle PTPRCAP PF15713.5 GBG67473.1 - 0.28 11.5 10.5 0.48 10.7 10.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated EP400_N PF15790.5 GBG67473.1 - 0.38 9.5 3.9 2.4 6.9 1.6 2.4 2 0 0 2 2 2 0 E1A-binding protein p400, N-terminal Nop14 PF04147.12 GBG67473.1 - 0.74 8.0 7.7 0.86 7.7 7.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG67473.1 - 0.75 8.0 7.5 0.93 7.7 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG67473.1 - 1.4 8.2 8.8 1.9 7.9 8.8 1.1 1 0 0 1 1 1 0 SDA1 RT_RNaseH_2 PF17919.1 GBG67474.1 - 1.3e-34 118.2 0.1 2e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67474.1 - 3.1e-30 104.6 0.1 4.9e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67474.1 - 2.9e-12 46.6 0.1 5e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG67475.1 - 1.6e-17 63.8 0.0 2.7e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG67475.1 - 9e-08 31.9 0.0 2.9e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG67475.1 - 0.0031 17.3 0.0 0.0073 16.1 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF5523 PF17661.1 GBG67476.1 - 7.5 6.2 33.8 10 5.7 33.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF913 PF06025.12 GBG67476.1 - 8.2 5.3 13.7 9.8 5.0 13.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 GBG67476.1 - 9.2 4.3 49.3 11 4.1 49.3 1.0 1 0 0 1 1 1 0 Nop14-like family Methyltransf_31 PF13847.6 GBG67478.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG67478.1 - 1.3e-07 32.2 0.0 2.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG67478.1 - 1.6e-05 25.6 0.0 4e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG67478.1 - 2.6e-05 24.1 0.0 3.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG67478.1 - 5.1e-05 23.9 0.0 0.00012 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GBG67478.1 - 0.0017 18.3 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 GBG67478.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF4411 PF14367.6 GBG67481.1 - 0.25 11.3 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) RT_RNaseH_2 PF17919.1 GBG67482.1 - 2.6e-35 120.4 0.0 4.7e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67482.1 - 2.3e-33 114.6 0.0 4e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67482.1 - 1.2e-06 28.3 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PQ-loop PF04193.14 GBG67483.1 - 8.9e-35 118.3 16.6 1.3e-18 66.6 2.7 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 GBG67483.1 - 0.025 15.4 2.4 0.26 12.1 0.1 2.3 1 1 1 2 2 2 0 ER lumen protein retaining receptor Asp_protease_2 PF13650.6 GBG67484.1 - 9.4e-09 35.8 0.2 4.4e-07 30.4 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67484.1 - 1.3e-07 32.1 1.0 1.6e-06 28.6 0.1 2.7 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG67484.1 - 0.00038 20.2 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease TFIIF_alpha PF05793.12 GBG67486.1 - 0.22 10.1 15.1 0.3 9.6 15.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Herpes_BLRF2 PF05812.12 GBG67487.1 - 0.12 12.6 14.9 0.05 13.8 4.0 3.1 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein HalX PF08663.10 GBG67487.1 - 0.27 11.6 0.3 0.27 11.6 0.3 3.1 2 2 1 3 3 3 0 HalX domain TSC22 PF01166.18 GBG67487.1 - 5.5 7.4 14.6 0.69 10.3 0.8 3.7 2 2 1 3 3 3 0 TSC-22/dip/bun family ZapB PF06005.12 GBG67487.1 - 9.3 6.8 23.3 0.38 11.2 4.9 3.2 2 1 0 2 2 2 0 Cell division protein ZapB zf-CCHC PF00098.23 GBG67488.1 - 7e-08 32.2 2.4 1.7e-07 31.0 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle GIY-YIG PF01541.24 GBG67488.1 - 0.0014 18.8 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-CCHC_5 PF14787.6 GBG67488.1 - 0.014 15.1 1.4 0.038 13.7 1.4 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RVT_1 PF00078.27 GBG67488.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG67490.1 - 2.1e-22 79.6 0.0 3.6e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) 5_nucleotid_C PF02872.18 GBG67491.1 - 0.083 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain AA_permease_2 PF13520.6 GBG67492.1 - 4.1e-38 131.3 17.7 4.1e-38 131.3 17.7 1.4 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 GBG67492.1 - 3e-16 59.1 23.2 3e-16 59.1 23.2 2.3 2 1 0 2 2 2 1 Amino acid permease DUF4020 PF13212.6 GBG67493.1 - 0.14 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) LCD1 PF09798.9 GBG67493.1 - 0.2 10.1 1.2 0.21 10.1 1.2 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Babuvirus_MP PF07234.11 GBG67493.1 - 1.4 9.1 3.4 5.5 7.2 1.4 2.3 2 0 0 2 2 2 0 Movement and RNA silencing protein SURF1 PF02104.15 GBG67494.1 - 9.7e-25 87.8 0.0 2e-18 67.3 0.0 2.5 2 1 0 2 2 2 2 SURF1 family DUF2681 PF10883.8 GBG67494.1 - 0.19 12.2 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PseudoU_synth_2 PF00849.22 GBG67496.1 - 9.7e-18 64.8 1.0 9.5e-13 48.5 0.1 3.1 3 0 0 3 3 3 2 RNA pseudouridylate synthase RVT_1 PF00078.27 GBG67497.1 - 1.4e-12 47.6 0.0 2.4e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67497.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain WD40 PF00400.32 GBG67498.1 - 3.2e-17 62.6 14.8 0.00033 21.4 0.5 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG67498.1 - 1.4e-05 25.3 0.0 0.9 9.9 0.0 4.0 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GBG67498.1 - 0.00016 22.0 0.2 6.5 7.4 0.0 4.1 4 0 0 4 4 4 2 PQQ-like domain PilZ PF07238.14 GBG67498.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.8 2 0 0 2 2 2 0 PilZ domain DctP PF03480.13 GBG67498.1 - 0.24 10.7 0.0 0.41 9.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 zf-CCHC PF00098.23 GBG67499.1 - 0.33 11.1 1.0 0.74 10.0 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle HTH_7 PF02796.15 GBG67501.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase GCN5L1 PF06320.13 GBG67501.1 - 0.17 12.0 2.2 0.26 11.4 2.2 1.3 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DDE_Tnp_4 PF13359.6 GBG67502.1 - 1.4e-30 106.0 0.0 8.2e-30 103.6 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67502.1 - 1.3e-13 51.0 0.0 2.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67502.1 - 0.0014 18.4 0.0 0.063 12.9 0.0 2.4 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG67504.1 - 4.4e-08 33.4 2.4 4.4e-08 33.4 2.4 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67504.1 - 0.058 13.7 0.6 0.14 12.4 0.6 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GHMP_kinases_C PF08544.13 GBG67505.1 - 0.15 12.5 0.1 0.44 10.9 0.1 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal CBM_48 PF02922.18 GBG67506.1 - 1.5e-16 60.5 0.0 4.3e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 GBG67506.1 - 4.5e-16 59.3 0.4 3.1e-06 27.0 0.1 4.2 3 1 1 4 4 4 4 Alpha amylase, catalytic domain Pur_ac_phosph_N PF16656.5 GBG67506.1 - 0.13 12.8 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain TF_Zn_Ribbon PF08271.12 GBG67508.1 - 0.0078 15.7 0.5 0.019 14.4 0.5 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2884 PF11101.8 GBG67508.1 - 0.055 13.0 3.1 1.6 8.2 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Rad50_zn_hook PF04423.14 GBG67508.1 - 0.06 13.2 0.3 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif C1_1 PF00130.22 GBG67508.1 - 0.17 11.8 0.3 0.34 10.8 0.3 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_hydro_47 PF01532.20 GBG67509.1 - 1.8e-123 412.9 0.1 1.3e-118 396.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 ALIX_LYPXL_bnd PF13949.6 GBG67509.1 - 0.027 13.8 0.2 0.051 12.9 0.2 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DivIC PF04977.15 GBG67509.1 - 0.098 12.4 0.1 0.28 11.0 0.1 1.8 1 0 0 1 1 1 0 Septum formation initiator Glyco_hydro_47 PF01532.20 GBG67510.1 - 4.2e-120 401.8 0.1 1.3e-97 327.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 ALIX_LYPXL_bnd PF13949.6 GBG67510.1 - 0.023 14.0 0.2 0.046 13.0 0.2 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DivIC PF04977.15 GBG67510.1 - 0.089 12.6 0.1 0.26 11.1 0.1 1.8 1 0 0 1 1 1 0 Septum formation initiator PRC PF05239.16 GBG67511.1 - 7.4e-12 45.2 0.1 1.8e-06 27.9 0.1 2.4 1 1 1 2 2 2 2 PRC-barrel domain CENP-B_dimeris PF09026.10 GBG67511.1 - 8.5 6.8 15.5 6.9 7.1 0.4 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Rxt3 PF08642.10 GBG67512.1 - 1.1e-13 52.0 0.1 1.1e-10 42.4 0.1 2.3 1 1 1 2 2 2 2 Histone deacetylation protein Rxt3 LCCL PF03815.19 GBG67512.1 - 0.00042 20.4 0.0 0.00084 19.4 0.0 1.5 1 0 0 1 1 1 1 LCCL domain Rxt3 PF08642.10 GBG67513.1 - 8.9e-14 52.4 0.1 9.6e-11 42.6 0.1 2.3 1 1 1 2 2 2 2 Histone deacetylation protein Rxt3 LCCL PF03815.19 GBG67513.1 - 0.00036 20.6 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 LCCL domain Rxt3 PF08642.10 GBG67514.1 - 8.9e-14 52.4 0.1 9.6e-11 42.6 0.1 2.3 1 1 1 2 2 2 2 Histone deacetylation protein Rxt3 LCCL PF03815.19 GBG67514.1 - 0.00036 20.6 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 LCCL domain Retrotrans_gag PF03732.17 GBG67516.1 - 3.9e-05 23.9 0.4 0.00051 20.3 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein EVI2A PF05399.11 GBG67519.1 - 0.036 13.6 3.5 0.061 12.9 3.5 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Nop53 PF07767.11 GBG67519.1 - 0.25 10.7 24.6 0.34 10.2 24.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GBG67519.1 - 0.4 8.8 26.9 0.46 8.6 26.9 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG67519.1 - 0.74 9.1 30.0 0.92 8.8 30.0 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG67519.1 - 0.77 9.1 27.7 0.96 8.8 27.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG67519.1 - 0.87 7.8 20.5 1.1 7.4 20.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG67519.1 - 1.4 8.6 21.1 1.8 8.3 21.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 GBG67519.1 - 2 7.1 7.9 2.1 7.0 7.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.12 GBG67519.1 - 2.1 6.8 26.9 2.8 6.4 26.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lin-8 PF03353.15 GBG67519.1 - 2.9 7.4 16.5 3.9 7.0 16.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 GBG67519.1 - 7.5 3.5 7.2 8.4 3.4 7.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Merozoite_SPAM PF07133.11 GBG67519.1 - 9.4 6.2 41.7 14 5.6 41.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Acetyltransf_10 PF13673.7 GBG67520.1 - 9.4e-07 28.8 0.0 1.3e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GBG67520.1 - 1.2e-06 28.7 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GBG67520.1 - 4.4e-06 27.0 0.0 5.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 GBG67520.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 GBG67520.1 - 0.0055 16.6 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF3884 PF13024.6 GBG67520.1 - 0.063 12.8 0.3 0.17 11.4 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3884) zf-CCHC PF00098.23 GBG67523.1 - 0.00011 22.1 5.4 0.00021 21.2 5.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG67523.1 - 0.08 12.7 2.9 0.17 11.6 2.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Methyltransf_22 PF13383.6 GBG67524.1 - 3.1e-22 79.4 0.7 1.1e-14 54.6 0.2 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.12 GBG67524.1 - 0.049 13.7 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase FkbM domain DUF521 PF04412.13 GBG67524.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) GATase_7 PF13537.6 GBG67527.1 - 9.6e-24 83.6 0.0 1.7e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GBG67527.1 - 4.7e-21 75.4 0.0 8.6e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 GBG67527.1 - 1.4e-09 37.6 0.2 3.3e-09 36.4 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 GBG67527.1 - 1.1e-08 34.3 0.0 2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 GBG67527.1 - 0.00077 18.3 0.0 0.003 16.3 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Prot_ATP_ID_OB PF16450.5 GBG67527.1 - 0.065 13.2 1.1 0.32 11.0 0.0 2.6 3 0 0 3 3 3 0 Proteasomal ATPase OB C-terminal domain MctB PF11382.8 GBG67527.1 - 0.14 11.9 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Csm1_N PF18504.1 GBG67528.1 - 0.0052 17.1 5.0 4.9 7.6 0.1 4.0 2 1 1 3 3 3 1 Csm1 N-terminal domain Atg14 PF10186.9 GBG67528.1 - 0.0095 15.0 4.3 0.67 9.0 0.0 3.3 3 0 0 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 PKcGMP_CC PF16808.5 GBG67528.1 - 0.022 14.6 3.2 30 4.6 0.0 4.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fez1 PF06818.15 GBG67528.1 - 0.065 13.7 5.6 1.2 9.6 0.0 3.2 2 1 0 2 2 2 0 Fez1 ATG16 PF08614.11 GBG67528.1 - 0.068 13.4 11.7 0.047 13.9 0.5 3.5 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 GBG67528.1 - 0.11 12.3 9.3 3.2 7.6 0.0 4.2 3 1 1 4 4 4 0 Septum formation initiator SlyX PF04102.12 GBG67528.1 - 0.16 12.6 11.2 54 4.5 0.1 6.5 7 0 0 7 7 6 0 SlyX AAA_13 PF13166.6 GBG67528.1 - 0.2 10.3 0.3 0.44 9.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain Sec2p PF06428.11 GBG67528.1 - 0.22 11.5 0.4 9.5 6.3 0.0 3.0 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Mto2_bdg PF12808.7 GBG67528.1 - 0.29 11.5 4.1 6.6 7.1 0.1 3.6 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF641 PF04859.12 GBG67528.1 - 0.32 11.3 6.1 0.94 9.8 0.2 3.4 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) DUF4201 PF13870.6 GBG67528.1 - 0.38 10.5 2.4 9.7 5.9 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) ERM PF00769.19 GBG67528.1 - 0.42 10.4 8.2 0.088 12.6 0.5 2.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 GBG67528.1 - 1 9.4 13.2 2.3 8.3 2.5 4.5 4 1 1 5 5 4 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 GBG67528.1 - 1.6 8.8 10.3 2.3 8.3 0.2 3.6 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 GBG67528.1 - 2 7.2 10.5 0.69 8.7 1.3 3.1 3 1 0 3 3 3 0 Spc7 kinetochore protein FAM76 PF16046.5 GBG67528.1 - 2.1 7.7 5.1 0.28 10.5 0.0 2.2 3 0 0 3 3 2 0 FAM76 protein APG6_N PF17675.1 GBG67528.1 - 2.8 8.5 9.0 59 4.2 0.6 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Wtap PF17098.5 GBG67528.1 - 3.8 7.4 5.5 30 4.5 0.3 3.4 3 0 0 3 3 3 0 WTAP/Mum2p family Lebercilin PF15619.6 GBG67528.1 - 4.8 6.8 5.4 35 4.0 0.3 3.1 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HIP1_clath_bdg PF16515.5 GBG67528.1 - 8.2 7.1 10.5 13 6.4 0.4 4.1 4 1 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_19 PF14559.6 GBG67529.1 - 0.0044 17.5 10.5 0.35 11.4 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG67529.1 - 0.0071 16.7 0.1 3.4 8.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat IMUP PF15761.5 GBG67529.1 - 0.35 11.6 6.9 0.31 11.7 3.6 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 GBG67529.1 - 0.37 10.4 6.2 0.91 9.1 6.2 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.23 GBG67531.1 - 0.16 12.1 4.1 0.089 12.9 2.1 1.7 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 GBG67532.1 - 4.8e-73 245.8 0.0 6.5e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG67532.1 - 5.8e-28 97.9 0.0 1.1e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GBG67532.1 - 8.7e-05 21.6 0.1 0.00018 20.6 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain DUF3659 PF12396.8 GBG67532.1 - 0.006 16.5 3.1 0.087 12.8 1.2 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3659) Big_3_2 PF12245.8 GBG67532.1 - 0.065 13.5 1.4 0.43 10.8 0.1 2.5 2 1 1 3 3 3 0 Bacterial Ig-like domain Kinase-like PF14531.6 GBG67532.1 - 0.11 11.8 0.0 0.7 9.1 0.1 1.9 1 1 1 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 GBG67532.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 GBG67532.1 - 0.12 11.7 0.2 0.34 10.2 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG67532.1 - 0.13 12.2 0.1 0.28 11.1 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family BUD22 PF09073.10 GBG67533.1 - 2 7.7 24.0 2.5 7.4 24.0 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GBG67533.1 - 2.4 7.8 20.0 3.4 7.3 20.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG67533.1 - 4.9 6.5 29.1 6.8 6.0 29.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG67533.1 - 5.9 5.0 26.0 7.9 4.5 26.0 1.1 1 0 0 1 1 1 0 Nop14-like family LVIVD PF08309.11 GBG67534.1 - 0.001 18.3 1.4 2.2 7.7 0.1 3.9 3 0 0 3 3 3 2 LVIVD repeat Kelch_6 PF13964.6 GBG67534.1 - 0.034 14.5 0.4 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Spot_14 PF07084.12 GBG67536.1 - 7.9 6.6 10.4 5.1 7.2 1.1 2.9 3 0 0 3 3 3 0 Thyroid hormone-inducible hepatic protein Spot 14 RT_RNaseH_2 PF17919.1 GBG67537.1 - 9.3e-23 80.2 0.1 5.8e-22 77.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67537.1 - 1.3e-22 80.1 0.0 2.9e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67537.1 - 2.2e-18 66.1 0.1 4.3e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67537.1 - 1.9e-15 57.0 0.1 2.8e-14 53.2 0.1 2.7 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG67537.1 - 7.2e-06 25.8 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67537.1 - 0.0046 17.6 0.0 0.02 15.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG67537.1 - 0.015 15.5 0.0 0.049 13.9 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG67538.1 - 3.1e-24 84.9 0.0 7.3e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67538.1 - 8.4e-23 80.7 0.1 2.5e-22 79.2 0.0 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67538.1 - 1.7e-08 34.3 0.2 1.7e-05 24.5 0.1 3.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG67538.1 - 5.9e-07 30.0 0.0 2.2e-06 28.2 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67538.1 - 1.3e-05 25.7 0.0 4.8e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG67538.1 - 2.1e-05 24.7 0.4 9e-05 22.7 0.2 2.2 2 0 0 2 2 2 1 Integrase core domain 2-Hacid_dh_C PF02826.19 GBG67538.1 - 7.2e-05 22.2 0.1 0.00015 21.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RVP_2 PF08284.11 GBG67538.1 - 0.00032 20.5 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease AlaDh_PNT_C PF01262.21 GBG67538.1 - 0.00044 19.6 0.4 0.00089 18.6 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Chromo PF00385.24 GBG67538.1 - 0.006 16.5 0.0 0.035 14.0 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG67538.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease XdhC_C PF13478.6 GBG67538.1 - 0.077 13.5 0.6 0.29 11.7 0.6 2.0 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 GBG67538.1 - 0.078 13.4 0.2 0.31 11.5 0.2 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding SPACA9 PF15120.6 GBG67538.1 - 0.08 12.7 1.4 0.18 11.6 1.4 1.5 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 3HCDH_N PF02737.18 GBG67538.1 - 0.49 10.3 1.9 0.89 9.4 0.2 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BLOC1_2 PF10046.9 GBG67538.1 - 1 9.7 6.4 0.48 10.8 2.8 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Retrotrans_gag PF03732.17 GBG67539.1 - 0.064 13.5 0.3 0.25 11.7 0.0 2.1 2 1 0 2 2 2 0 Retrotransposon gag protein Trimer_CC PF08954.11 GBG67539.1 - 0.13 11.9 0.6 0.26 10.9 0.6 1.5 1 0 0 1 1 1 0 Trimerisation motif Mur_ligase_M PF08245.12 GBG67540.1 - 2.1e-17 63.8 0.0 2.1e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Mur ligase middle domain RVT_1 PF00078.27 GBG67541.1 - 3.9e-25 88.7 0.0 1.1e-24 87.2 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG67541.1 - 7.5e-08 32.9 0.0 2.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67541.1 - 1.3e-05 25.7 0.0 3.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67541.1 - 0.00037 20.3 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67541.1 - 0.0026 17.6 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG67541.1 - 0.0038 17.5 0.1 0.036 14.3 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG67541.1 - 0.061 13.2 1.1 0.076 12.9 0.0 1.7 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG67542.1 - 1.3e-25 89.7 0.1 2.8e-25 88.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67542.1 - 3.9e-25 87.8 0.0 8.3e-25 86.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67542.1 - 8.5e-10 38.9 0.0 2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG67542.1 - 9.4e-06 25.4 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67542.1 - 6.9e-05 23.4 0.0 0.00014 22.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG67542.1 - 0.00014 21.4 0.2 0.05 13.1 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG67542.1 - 0.0061 17.1 0.0 0.019 15.5 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG67542.1 - 0.0086 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG67542.1 - 0.069 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Asp_protease PF09668.10 GBG67542.1 - 0.19 11.5 0.0 0.46 10.3 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease DUF4392 PF14336.6 GBG67542.1 - 0.26 10.7 0.0 0.43 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) RT_RNaseH_2 PF17919.1 GBG67543.1 - 1.2e-22 79.8 0.0 2.5e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67543.1 - 2.5e-19 69.5 0.0 8e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67543.1 - 1.4e-08 34.9 0.0 2.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG67543.1 - 0.00071 20.1 0.0 0.0019 18.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67543.1 - 0.0012 19.4 0.0 0.0029 18.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG67543.1 - 0.0014 18.8 0.1 0.0068 16.7 0.0 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein RVP PF00077.20 GBG67543.1 - 0.012 16.0 0.0 0.038 14.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Rx_N PF18052.1 GBG67543.1 - 0.059 13.7 0.1 5.8 7.3 0.0 3.4 3 0 0 3 3 3 0 Rx N-terminal domain Mur_ligase_C PF02875.21 GBG67544.1 - 8.7e-06 25.9 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Nop53 PF07767.11 GBG67545.1 - 0.012 15.0 22.2 0.021 14.2 22.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4551 PF15087.6 GBG67545.1 - 0.13 11.0 1.8 0.17 10.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Nop14 PF04147.12 GBG67545.1 - 0.15 10.2 26.1 0.2 9.8 26.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG67545.1 - 0.35 10.2 25.7 0.51 9.7 25.7 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG67545.1 - 0.66 8.2 21.3 0.91 7.7 21.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GBG67545.1 - 0.68 8.7 7.7 0.91 8.2 7.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.11 GBG67545.1 - 3.6 6.9 9.9 5.3 6.4 9.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TP53IP5 PF15331.6 GBG67545.1 - 4.7 7.3 7.3 8.3 6.5 7.3 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 BUD22 PF09073.10 GBG67545.1 - 5.1 6.3 24.7 7.1 5.9 24.7 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 GBG67545.1 - 7.4 4.5 25.3 12 3.8 25.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi RT_RNaseH_2 PF17919.1 GBG67546.1 - 3.9e-34 116.7 0.0 7.8e-34 115.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67546.1 - 4.3e-29 100.9 0.0 8.4e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG67546.1 - 2.5e-08 33.6 1.2 4.5e-08 32.8 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG67546.1 - 0.0075 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG67546.1 - 0.024 14.4 2.7 0.048 13.5 2.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Josephin PF02099.17 GBG67547.1 - 1.8 8.6 4.0 3.8 7.6 4.0 1.5 1 0 0 1 1 1 0 Josephin Cep57_CLD_2 PF14197.6 GBG67548.1 - 0.00089 19.3 4.3 0.4 10.8 0.4 2.3 2 0 0 2 2 2 2 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 GBG67548.1 - 0.0017 18.4 2.5 0.0024 17.9 2.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATP-synt_D PF01813.17 GBG67548.1 - 0.014 15.2 2.3 0.022 14.6 2.3 1.2 1 0 0 1 1 1 0 ATP synthase subunit D TPR_MLP1_2 PF07926.12 GBG67548.1 - 0.079 13.0 0.9 0.12 12.5 0.9 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 GBG67548.1 - 0.37 11.3 3.3 3.7 8.1 2.7 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DUF1192 PF06698.11 GBG67548.1 - 0.5 10.5 5.6 2.6 8.2 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF4164 PF13747.6 GBG67548.1 - 0.63 10.4 8.7 1.7 9.0 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) bZIP_Maf PF03131.17 GBG67548.1 - 5.7 7.5 9.3 0.67 10.5 0.2 2.6 3 0 0 3 3 3 0 bZIP Maf transcription factor Pes-10 PF07149.11 GBG67549.1 - 0.0049 16.0 5.1 0.0073 15.4 5.1 1.2 1 0 0 1 1 1 1 Pes-10 Trypan_PARP PF05887.11 GBG67549.1 - 0.2 11.7 12.8 0.37 10.8 12.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.12 GBG67549.1 - 0.56 9.6 15.3 0.82 9.0 15.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG67549.1 - 0.6 8.3 16.6 0.87 7.7 16.6 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG67549.1 - 0.92 8.8 11.9 1.3 8.3 11.9 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 GBG67549.1 - 1.3 7.0 3.0 1.8 6.5 3.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CobT PF06213.12 GBG67549.1 - 2.2 7.6 15.5 4.8 6.5 15.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DEK_C PF08766.11 GBG67550.1 - 0.0089 15.9 0.1 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 DEK C terminal domain REV PF00424.18 GBG67551.1 - 0.063 13.3 0.7 0.063 13.3 0.7 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Cwf_Cwc_15 PF04889.12 GBG67551.1 - 3.6 7.3 31.0 5.3 6.7 31.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BAF1_ABF1 PF04684.13 GBG67551.1 - 5.9 5.8 17.8 7.4 5.5 17.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3500 PF12006.8 GBG67551.1 - 8.7 5.7 7.7 8.7 5.7 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3500) RVT_1 PF00078.27 GBG67555.1 - 2.8e-31 108.8 0.0 4.7e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PUB PF09409.10 GBG67556.1 - 5.5e-23 80.7 0.0 1.4e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 PUB domain UBA PF00627.31 GBG67556.1 - 5.3e-10 39.0 0.2 2e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 GBG67556.1 - 0.0048 17.2 5.0 0.64 10.4 0.9 2.7 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) DZR PF12773.7 GBG67556.1 - 0.081 13.0 1.1 0.18 11.9 1.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon MCM3AP_GANP PF16769.5 GBG67556.1 - 0.081 11.2 9.4 0.12 10.6 9.4 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP Chordopox_RPO7 PF05864.12 GBG67556.1 - 0.15 12.3 1.0 2.2 8.6 0.1 2.6 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-C2H2_aberr PF17017.5 GBG67556.1 - 0.17 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger DUF4778 PF16008.5 GBG67556.1 - 0.56 10.2 8.1 0.97 9.4 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Histone PF00125.24 GBG67557.1 - 5.5e-07 30.0 0.4 1.4e-06 28.7 0.2 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PPP4R2 PF09184.11 GBG67557.1 - 0.28 10.8 6.9 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 PPP4R2 Bin3 PF06859.12 GBG67558.1 - 1.7e-30 105.9 0.0 2.9e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 GBG67558.1 - 9.6e-10 39.1 0.0 6e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GBG67558.1 - 2.9e-08 33.7 1.4 3e-07 30.4 1.4 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG67558.1 - 4e-08 33.8 0.0 0.016 15.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GBG67558.1 - 1.8e-06 28.6 0.0 0.008 16.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GBG67558.1 - 4.1e-05 23.4 0.1 0.00048 20.0 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GBG67558.1 - 0.0043 16.5 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 GBG67558.1 - 0.03 13.8 0.0 0.083 12.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 GBG67558.1 - 0.038 13.6 0.0 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain CheR PF01739.18 GBG67558.1 - 0.053 13.0 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.7 GBG67558.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HSP70 PF00012.20 GBG67559.1 - 1.8e-178 594.5 3.8 2.6e-178 593.9 0.0 2.3 3 0 0 3 3 3 1 Hsp70 protein MreB_Mbl PF06723.13 GBG67559.1 - 6.2e-11 41.7 0.6 2.4e-09 36.5 0.2 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG67559.1 - 2e-05 24.4 0.0 6.2e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG67559.1 - 0.006 17.0 1.0 7.7 7.0 0.0 3.8 4 0 0 4 4 4 2 Cell division protein FtsA DDR PF08841.10 GBG67559.1 - 0.23 10.4 1.7 13 4.7 0.0 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Histone PF00125.24 GBG67561.1 - 0.00056 20.3 0.2 0.00056 20.3 0.2 3.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 Aconitase_2_N PF06434.13 GBG67561.1 - 0.032 13.9 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus RFXA_RFXANK_bdg PF15289.6 GBG67561.1 - 1.2 9.5 4.3 3.5 8.0 4.3 1.8 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain UPF0242 PF06785.11 GBG67563.1 - 0.036 14.2 9.7 0.56 10.3 7.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HNOBA PF07701.14 GBG67563.1 - 3.6 7.0 6.4 6.6 6.1 6.4 1.4 1 0 0 1 1 1 0 Heme NO binding associated AAA_23 PF13476.6 GBG67563.1 - 4 7.9 11.7 1.2 9.5 8.5 1.7 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 GBG67563.1 - 4.4 5.7 10.8 7.2 5.0 10.8 1.3 1 0 0 1 1 1 0 Macoilin family HSP70 PF00012.20 GBG67564.1 - 4.3e-156 520.6 0.0 3.3e-116 388.9 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG67564.1 - 5.7e-07 28.7 0.2 5.2e-05 22.2 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG67564.1 - 6.8e-06 25.9 0.0 2.5e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG67564.1 - 0.00045 20.6 0.5 1.2 9.6 0.0 3.7 4 0 0 4 4 4 2 Cell division protein FtsA DDR PF08841.10 GBG67564.1 - 0.061 12.3 1.9 5.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Dynamin_M PF01031.20 GBG67565.1 - 5.6e-31 107.8 0.5 5.6e-31 107.8 0.5 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 GBG67565.1 - 1.2e-20 74.2 0.6 2.7e-20 73.1 0.6 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GBG67565.1 - 1.1e-05 25.5 0.3 1.1e-05 25.5 0.3 2.9 4 0 0 4 4 4 1 Dynamin GTPase effector domain Lactonase PF10282.9 GBG67567.1 - 0.0049 16.2 0.0 0.14 11.4 0.0 3.1 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller NHL PF01436.21 GBG67567.1 - 0.012 15.6 0.3 9.4 6.5 0.0 2.9 2 0 0 2 2 2 0 NHL repeat TcA_TcB_BD PF18276.1 GBG67567.1 - 0.049 12.7 0.0 7.1 5.6 0.0 2.5 2 0 0 2 2 2 0 Tc toxin complex TcA C-terminal TcB-binding domain PD40 PF07676.12 GBG67567.1 - 0.05 13.5 0.0 26 4.9 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Myb_DNA-bind_4 PF13837.6 GBG67568.1 - 5.4e-09 36.3 5.5 1.3e-07 31.8 2.6 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67568.1 - 0.0014 18.9 3.5 0.0075 16.6 1.9 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like LapA_dom PF06305.11 GBG67568.1 - 0.031 14.1 0.8 0.07 12.9 0.8 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MAP17 PF15807.5 GBG67568.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Comm PF15957.5 GBG67568.1 - 0.095 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Commissureless Peptidase_M56 PF05569.11 GBG67568.1 - 0.12 11.6 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 DDE_Tnp_4 PF13359.6 GBG67569.1 - 5.8e-25 87.8 0.0 2.1e-24 86.0 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67569.1 - 4.1e-12 46.1 0.0 6.3e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67569.1 - 0.0014 18.3 0.4 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG67569.1 - 0.023 15.1 0.0 0.095 13.1 0.0 2.0 1 0 0 1 1 1 0 Transposase DDE domain BTHB PF18410.1 GBG67570.1 - 0.023 14.5 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Basic tilted helix bundle domain Pkinase PF00069.25 GBG67573.1 - 6.5e-33 114.2 0.0 1.5e-32 113.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG67573.1 - 3e-32 111.9 0.0 1.4e-31 109.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG67573.1 - 1.8e-06 28.1 0.2 0.00026 21.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG67573.1 - 0.0079 15.0 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RT_RNaseH_2 PF17919.1 GBG67574.1 - 1e-23 83.3 0.0 1.8e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67574.1 - 1.6e-22 79.7 0.0 2.9e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67574.1 - 1.8e-06 27.6 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTPRCAP PF15713.5 GBG67574.1 - 0.35 11.2 11.1 0.66 10.3 11.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG67574.1 - 0.52 8.5 9.9 0.75 8.0 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG67574.1 - 3.3 7.1 11.0 4.5 6.6 11.0 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG67574.1 - 3.3 7.0 14.8 4.8 6.4 14.8 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG67574.1 - 6.2 4.9 11.9 8.2 4.5 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG67577.1 - 4.1e-62 209.6 0.3 9.5e-33 113.6 0.1 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67577.1 - 1.1e-47 160.2 0.2 5.2e-27 93.8 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67577.1 - 1e-35 122.2 0.0 3.1e-24 85.3 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67577.1 - 7.4e-18 64.4 0.4 1.6e-17 63.3 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG67577.1 - 2.8e-16 59.5 0.0 1.1e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67577.1 - 2.7e-13 50.4 0.0 1.3e-05 25.7 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG67577.1 - 2.7e-13 50.3 0.0 7e-06 26.5 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG67577.1 - 3.5e-08 33.3 0.0 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease rve PF00665.26 GBG67577.1 - 2.6e-07 30.8 0.2 1.2e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG67577.1 - 0.0051 16.7 0.0 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Retrotrans_gag PF03732.17 GBG67577.1 - 0.013 15.8 0.0 0.048 13.9 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Chromo PF00385.24 GBG67577.1 - 0.027 14.4 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Phage_GPO PF05929.11 GBG67577.1 - 0.098 12.3 0.2 6 6.4 0.0 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HrpB7 PF09486.10 GBG67577.1 - 1 9.8 5.5 1 9.7 3.6 2.0 2 0 0 2 2 1 0 Bacterial type III secretion protein (HrpB7) FixH PF05751.11 GBG67578.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 FixH TPT PF03151.16 GBG67579.1 - 3.3e-101 338.5 22.5 4.1e-101 338.2 22.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG67579.1 - 3.9e-07 30.3 29.2 0.00021 21.5 11.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family Macoilin PF09726.9 GBG67580.1 - 8.5 4.8 17.3 12 4.4 17.3 1.2 1 0 0 1 1 1 0 Macoilin family Retrotrans_gag PF03732.17 GBG67581.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG67582.1 - 3.2e-31 107.3 0.0 6.9e-31 106.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67582.1 - 3.3e-31 108.5 0.0 5.3e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67582.1 - 1.7e-26 92.5 0.0 3.3e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG67582.1 - 0.00023 21.7 0.2 0.00065 20.2 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67582.1 - 0.0093 16.6 0.2 0.027 15.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG67582.1 - 0.041 13.7 0.0 0.041 13.7 0.0 1.8 2 0 0 2 2 2 0 Putative peptidase (DUF1758) RRT14 PF17075.5 GBG67582.1 - 0.064 13.4 2.9 0.12 12.5 2.9 1.3 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 DUF5095 PF17016.5 GBG67582.1 - 0.13 11.9 1.0 0.6 9.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) PET PF06297.14 GBG67582.1 - 0.18 12.1 0.7 1.3 9.4 0.5 2.3 2 0 0 2 2 2 0 PET Domain RT_RNaseH_2 PF17919.1 GBG67583.1 - 7e-29 99.8 0.0 7.6e-17 61.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67583.1 - 1.1e-24 86.7 0.0 2.7e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67583.1 - 1.8e-19 70.1 0.1 3.7e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67583.1 - 1.1e-06 28.8 0.0 5e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG67583.1 - 3.5e-05 23.6 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PCO_ADO PF07847.12 GBG67584.1 - 1.6e-63 213.8 0.0 1.9e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO RVT_1 PF00078.27 GBG67585.1 - 1.7e-35 122.6 0.3 4.1e-31 108.2 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67585.1 - 6.8e-35 119.0 0.7 3.3e-18 65.6 0.3 3.4 3 0 0 3 3 3 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG67585.1 - 1e-28 99.7 0.3 9.1e-18 64.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67585.1 - 7.6e-27 93.9 0.0 1.4e-13 51.1 0.0 3.0 3 0 0 3 3 3 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG67585.1 - 1.1e-26 92.8 0.0 3.3e-23 81.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG67585.1 - 1.2e-06 28.7 0.0 0.013 15.7 0.0 3.2 3 0 0 3 3 3 2 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG67585.1 - 0.02 15.1 0.5 1.8 8.9 0.0 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein rve_3 PF13683.6 GBG67585.1 - 0.037 13.8 0.0 2.3 8.1 0.0 2.9 2 0 0 2 2 2 0 Integrase core domain DUF3417 PF11897.8 GBG67585.1 - 0.054 14.0 0.2 19 5.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) Dimer_Tnp_hAT PF05699.14 GBG67586.1 - 2.1e-12 46.6 3.6 4.4e-11 42.4 3.6 2.8 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG67587.1 - 0.0025 18.4 0.1 0.005 17.4 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67587.1 - 0.015 15.9 0.1 0.029 15.0 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG67587.1 - 0.038 13.8 0.2 0.07 12.9 0.2 1.4 1 0 0 1 1 1 0 Aspartyl protease ICA69 PF04629.14 GBG67587.1 - 0.16 12.2 3.8 0.21 11.9 3.8 1.1 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain RXLR PF16810.5 GBG67587.1 - 1.3 9.5 5.3 1.8 9.0 5.3 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Cid2 PF09774.9 GBG67587.1 - 1.8 9.0 10.4 2.9 8.3 10.4 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 PRTP PF01366.18 GBG67587.1 - 4.9 5.1 5.4 6.3 4.7 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein FAM176 PF14851.6 GBG67587.1 - 6.4 6.4 8.1 9.7 5.8 8.1 1.2 1 0 0 1 1 1 0 FAM176 family PX PF00787.24 GBG67588.1 - 8.7e-24 83.7 0.4 2.4e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 GBG67588.1 - 2.4e-20 73.1 7.6 1e-19 71.0 7.6 1.9 1 1 0 1 1 1 1 Vps5 C terminal like DUF3824 PF12868.7 GBG67588.1 - 0.36 11.5 0.9 0.9 10.2 0.9 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) PPTA PF01239.22 GBG67589.1 - 4.4e-07 29.4 7.2 0.0011 18.7 0.1 4.1 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat RVT_1 PF00078.27 GBG67590.1 - 3.5e-25 88.8 0.1 6.5e-25 88.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67590.1 - 8.3e-25 86.7 0.0 2.3e-24 85.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67590.1 - 6.5e-16 58.5 0.0 1.9e-15 57.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG67590.1 - 0.0011 19.2 0.0 0.0062 16.8 0.0 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein APG17 PF04108.12 GBG67590.1 - 0.044 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 LegC3_N PF18654.1 GBG67592.1 - 0.075 12.3 1.9 0.097 11.9 1.9 1.1 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain PNISR PF15996.5 GBG67593.1 - 0.02 15.2 2.3 0.02 15.2 2.3 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SDA1 PF05285.12 GBG67593.1 - 0.042 13.3 26.1 0.048 13.1 26.1 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG67593.1 - 0.23 10.8 28.8 0.27 10.6 28.8 1.1 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 GBG67593.1 - 2.6 6.7 5.0 3.2 6.5 5.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 GBG67593.1 - 5.5 5.1 33.4 6.5 4.8 33.4 1.0 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.32 GBG67594.1 - 7e-43 143.8 6.5 8.1e-09 36.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 GBG67594.1 - 3.5e-13 48.8 6.9 9.9e-13 47.4 6.9 1.9 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 GBG67594.1 - 6.6e-10 39.2 0.0 0.0085 16.4 0.0 5.7 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG67594.1 - 6e-05 22.5 0.0 0.029 13.7 0.0 2.4 1 1 1 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 GBG67594.1 - 0.00074 18.6 0.0 0.18 10.7 0.0 3.4 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GBG67594.1 - 0.03 13.0 0.4 14 4.1 0.0 4.0 3 1 2 5 5 5 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 GBG67594.1 - 0.053 12.8 0.0 0.4 10.0 0.0 2.4 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal V-ATPase_C PF03223.15 GBG67595.1 - 1e-94 318.0 0.0 1.2e-94 317.7 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C AAA_33 PF13671.6 GBG67596.1 - 2.5e-22 79.6 0.0 5.2e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain SPRY PF00622.28 GBG67596.1 - 7.1e-06 26.1 0.0 7.1e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 SPRY domain Zeta_toxin PF06414.12 GBG67596.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 GBG67596.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 GBG67596.1 - 0.18 12.3 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF525 PF04379.14 GBG67597.1 - 6.1e-24 84.1 0.0 2e-22 79.3 0.0 2.3 2 0 0 2 2 2 1 ApaG domain F-box-like PF12937.7 GBG67597.1 - 1.8e-07 30.9 2.8 7.3e-07 29.0 0.5 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GBG67597.1 - 0.099 12.6 0.3 0.2 11.6 0.3 1.6 1 0 0 1 1 1 0 F-box domain SMI1_KNR4 PF09346.10 GBG67597.1 - 0.14 12.5 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Glu_cyclase_2 PF05096.12 GBG67598.1 - 1.7e-87 293.0 0.0 2.2e-87 292.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase SGL PF08450.12 GBG67598.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GBG67598.1 - 0.12 12.5 0.1 14 6.0 0.0 3.3 4 0 0 4 4 4 0 NHL repeat YbaB_DNA_bd PF02575.16 GBG67599.1 - 5e-19 68.3 3.5 8.1e-19 67.6 3.5 1.3 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Presenilin PF01080.17 GBG67601.1 - 0.39 9.4 0.8 0.67 8.6 0.8 1.3 1 0 0 1 1 1 0 Presenilin zf-CCHC PF00098.23 GBG67601.1 - 8.7 6.6 8.7 0.43 10.8 1.7 2.3 2 0 0 2 2 2 0 Zinc knuckle Pox_Ag35 PF03286.14 GBG67601.1 - 9.2 6.0 9.3 19 5.0 9.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SPRY PF00622.28 GBG67603.1 - 0.00072 19.7 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF2076 PF09849.9 GBG67604.1 - 5.6 6.9 9.9 9.4 6.2 9.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF659 PF04937.15 GBG67605.1 - 4.1e-15 56.0 0.0 9.9e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4407 PF14362.6 GBG67605.1 - 6.9 5.9 20.6 17 4.6 20.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG67608.1 - 6.6e-32 110.8 0.1 1.2e-31 109.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG67608.1 - 9.1e-31 106.8 0.7 1.7e-30 105.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG67608.1 - 1e-21 76.8 0.0 2.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67608.1 - 6.6e-11 42.4 0.0 1.8e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase IFT43 PF15305.6 GBG67610.1 - 3.2e-24 85.6 1.8 4.4e-24 85.2 1.3 1.5 1 1 1 2 2 2 1 Intraflagellar transport protein 43 AAA_5 PF07728.14 GBG67611.1 - 1e-13 51.5 0.1 3.4e-07 30.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 GBG67611.1 - 0.00018 21.6 0.0 0.00065 19.8 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 GBG67611.1 - 0.00026 21.4 0.1 0.0029 18.0 0.1 2.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_lid_7 PF17867.1 GBG67611.1 - 0.00085 19.5 1.6 0.56 10.4 0.2 4.1 4 0 0 4 4 4 1 Midasin AAA lid domain VWA_2 PF13519.6 GBG67611.1 - 0.014 16.1 0.1 0.064 13.9 0.1 2.3 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA_33 PF13671.6 GBG67611.1 - 0.039 14.1 0.0 0.15 12.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GBG67612.1 - 1.1e-94 313.7 0.0 1.3e-22 80.3 0.0 6.5 6 0 0 6 6 6 6 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 GBG67612.1 - 3.9e-37 126.7 0.3 2e-19 69.8 0.0 4.9 4 0 0 4 4 4 2 Midasin AAA lid domain AAA_lid_5 PF17865.1 GBG67612.1 - 3.8e-31 107.3 0.0 1.1e-30 105.8 0.0 1.9 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 GBG67612.1 - 1e-24 86.9 0.0 2.2e-05 24.3 0.0 6.3 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 GBG67612.1 - 2.9e-23 82.7 0.0 2.4e-05 24.8 0.0 4.9 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GBG67612.1 - 5.2e-22 78.2 0.1 7.3e-07 28.9 0.0 4.5 4 0 0 4 4 4 4 P-loop containing dynein motor region AAA_16 PF13191.6 GBG67612.1 - 1.1e-16 61.7 23.5 4.3e-05 23.9 2.9 7.3 5 3 0 6 6 5 4 AAA ATPase domain AAA_22 PF13401.6 GBG67612.1 - 5e-15 56.0 0.1 0.0039 17.5 0.0 6.0 5 0 0 5 5 5 4 AAA domain Sigma54_activat PF00158.26 GBG67612.1 - 1e-14 54.6 0.0 0.0038 16.9 0.0 5.0 5 0 0 5 5 5 4 Sigma-54 interaction domain Dynein_heavy PF03028.15 GBG67612.1 - 2.1e-13 50.4 0.0 0.14 12.2 0.0 6.5 6 0 0 6 6 6 2 Dynein heavy chain region D6 P-loop domain AAA_14 PF13173.6 GBG67612.1 - 2.9e-13 50.0 0.0 0.0013 18.8 0.0 5.5 5 0 0 5 5 5 3 AAA domain TsaE PF02367.17 GBG67612.1 - 5.4e-13 49.0 0.4 0.025 14.6 0.0 4.5 4 0 0 4 4 4 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 GBG67612.1 - 3.8e-12 46.9 0.2 0.098 13.2 0.0 5.3 5 0 0 5 5 4 3 AAA domain AAA_30 PF13604.6 GBG67612.1 - 6.1e-12 45.7 0.7 0.064 13.0 0.4 6.0 7 0 0 7 7 6 2 AAA domain AAA_6 PF12774.7 GBG67612.1 - 2.2e-11 43.3 0.0 0.045 12.7 0.0 5.8 5 2 0 5 5 5 3 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 GBG67612.1 - 9.3e-11 42.1 0.2 1.3 9.2 0.1 5.4 4 1 0 4 4 4 4 AAA domain RuvB_N PF05496.12 GBG67612.1 - 1.5e-10 41.0 0.6 0.78 9.5 0.0 5.7 5 0 0 5 5 5 2 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 GBG67612.1 - 2.2e-10 40.1 0.8 0.00086 18.4 0.0 4.3 4 0 0 4 4 4 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 GBG67612.1 - 1.4e-09 38.1 0.1 0.85 9.5 0.0 4.4 4 0 0 4 4 4 2 RsgA GTPase NACHT PF05729.12 GBG67612.1 - 4.8e-09 36.4 0.0 0.75 9.7 0.0 4.8 4 0 0 4 4 4 2 NACHT domain Zeta_toxin PF06414.12 GBG67612.1 - 9.1e-09 34.9 0.1 0.39 10.0 0.0 4.8 4 1 0 4 4 4 1 Zeta toxin Mg_chelatase PF01078.21 GBG67612.1 - 1.6e-08 34.2 0.2 1.4 8.2 0.0 7.0 7 0 0 7 7 7 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GBG67612.1 - 2.6e-08 34.2 0.0 1.1 9.7 0.0 4.5 4 0 0 4 4 4 1 RNA helicase IstB_IS21 PF01695.17 GBG67612.1 - 3.8e-08 33.2 0.4 0.42 10.3 0.0 4.7 5 0 0 5 5 4 1 IstB-like ATP binding protein AAA_19 PF13245.6 GBG67612.1 - 5.2e-08 33.4 3.6 2.3 8.5 0.0 5.9 6 0 0 6 6 5 2 AAA domain AAA_29 PF13555.6 GBG67612.1 - 5.2e-08 32.5 0.0 0.82 9.5 0.0 4.7 4 0 0 4 4 4 1 P-loop containing region of AAA domain AAA_28 PF13521.6 GBG67612.1 - 6.6e-08 33.0 0.1 0.47 10.7 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.6 GBG67612.1 - 8.1e-08 32.1 0.2 3.5 7.1 0.0 5.0 5 0 0 5 5 4 0 AAA domain DUF815 PF05673.13 GBG67612.1 - 3.1e-07 29.8 0.3 0.52 9.4 0.0 4.7 5 0 0 5 5 4 2 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 GBG67612.1 - 6e-07 29.7 0.0 0.0076 16.4 0.0 4.3 4 0 0 4 4 3 1 Sigma-54 interaction domain ABC_tran PF00005.27 GBG67612.1 - 6.8e-07 29.9 0.0 0.26 11.8 0.0 4.6 4 0 0 4 4 4 1 ABC transporter CPT PF07931.12 GBG67612.1 - 9.7e-06 25.5 4.1 1.6 8.6 0.1 6.7 6 1 0 6 6 5 1 Chloramphenicol phosphotransferase-like protein AAA_2 PF07724.14 GBG67612.1 - 1.7e-05 25.0 0.0 1.2 9.3 0.0 4.7 5 0 0 5 5 4 1 AAA domain (Cdc48 subfamily) MCM PF00493.23 GBG67612.1 - 2.3e-05 23.6 0.1 0.72 8.9 0.0 4.4 4 0 0 4 4 4 1 MCM P-loop domain Rad17 PF03215.15 GBG67612.1 - 6e-05 23.0 0.2 1.4 8.8 0.0 4.0 4 0 0 4 4 4 1 Rad17 P-loop domain AAA_11 PF13086.6 GBG67612.1 - 0.00011 22.0 1.7 2.8 7.6 0.0 4.5 5 0 0 5 5 4 1 AAA domain NTPase_1 PF03266.15 GBG67612.1 - 0.00016 21.6 2.8 9.2 6.2 0.0 4.9 5 0 0 5 5 5 0 NTPase TIP49 PF06068.13 GBG67612.1 - 0.00022 20.5 0.1 0.67 9.1 0.0 3.7 4 0 0 4 4 4 1 TIP49 P-loop domain TniB PF05621.11 GBG67612.1 - 0.00026 20.5 0.1 3 7.2 0.0 4.2 4 0 0 4 4 4 0 Bacterial TniB protein ATPase PF06745.13 GBG67612.1 - 0.00027 20.3 0.1 1.8 7.8 0.0 3.4 4 0 0 4 4 3 2 KaiC AAA_8 PF12780.7 GBG67612.1 - 0.00036 20.0 0.1 3.9 6.7 0.0 3.5 3 0 0 3 3 3 0 P-loop containing dynein motor region D4 ATPase_2 PF01637.18 GBG67612.1 - 0.00038 20.4 0.0 19 5.1 0.0 4.4 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 GBG67612.1 - 0.0004 21.0 0.0 25 5.3 0.0 4.4 5 0 0 5 5 4 0 AAA domain MMR_HSR1 PF01926.23 GBG67612.1 - 0.00043 20.3 0.0 7.2 6.7 0.0 4.4 4 0 0 4 4 4 0 50S ribosome-binding GTPase Roc PF08477.13 GBG67612.1 - 0.00044 20.4 0.1 23 5.2 0.0 4.3 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 GBG67612.1 - 0.0011 18.5 0.1 12 5.4 0.0 4.4 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 GBG67612.1 - 0.0021 17.5 0.0 2.6 7.5 0.0 3.4 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 GBG67612.1 - 0.0024 17.1 0.1 5 6.2 0.0 3.6 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 GBG67612.1 - 0.0031 17.3 0.0 40 3.8 0.0 4.3 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.9 GBG67612.1 - 0.0081 15.9 0.0 6.6 6.5 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 GBG67612.1 - 0.016 14.6 0.4 4.5 6.5 0.0 3.7 4 0 0 4 4 4 0 DnaB-like helicase C terminal domain IPT PF01745.16 GBG67612.1 - 0.018 14.5 0.1 1.9 7.8 0.0 2.8 3 0 0 3 3 2 0 Isopentenyl transferase dNK PF01712.19 GBG67612.1 - 0.022 14.6 0.3 3.5 7.4 0.0 3.6 4 0 0 4 4 4 0 Deoxynucleoside kinase ResIII PF04851.15 GBG67612.1 - 0.041 13.9 0.1 1.5 8.8 0.0 3.3 5 0 0 5 5 3 0 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG67612.1 - 0.045 13.5 0.0 2.3 7.9 0.0 2.9 3 0 0 3 3 2 0 DEAD/DEAH box helicase Bac_DnaA PF00308.18 GBG67612.1 - 0.061 13.2 0.0 15 5.4 0.0 3.5 5 0 0 5 5 3 0 Bacterial dnaA protein PhoH PF02562.16 GBG67612.1 - 0.084 12.3 0.0 3.5 7.0 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein Guanylate_kin PF00625.21 GBG67612.1 - 0.099 12.3 0.5 26 4.4 0.0 3.6 4 0 0 4 4 3 0 Guanylate kinase Cytidylate_kin PF02224.18 GBG67612.1 - 0.12 12.1 0.3 11 5.7 0.0 3.7 4 0 0 4 4 4 0 Cytidylate kinase DAP3 PF10236.9 GBG67612.1 - 0.15 11.2 0.0 34 3.5 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_PrkA PF08298.11 GBG67612.1 - 0.17 10.8 0.0 6 5.7 0.0 2.8 3 0 0 3 3 3 0 PrkA AAA domain Asp_protease_2 PF13650.6 GBG67614.1 - 7.8e-07 29.6 0.0 5.4e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG67614.1 - 4e-05 23.4 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG67614.1 - 7.3e-05 23.3 0.0 0.00063 20.3 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG67614.1 - 0.0021 17.8 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG67614.1 - 0.0031 17.8 0.0 0.011 16.0 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein SlyX PF04102.12 GBG67614.1 - 0.017 15.7 1.7 0.017 15.7 1.7 2.9 2 1 1 3 3 2 0 SlyX MIF4G_like_2 PF09090.11 GBG67614.1 - 0.046 13.2 0.3 0.078 12.4 0.3 1.3 1 0 0 1 1 1 0 MIF4G like TolA_bind_tri PF16331.5 GBG67614.1 - 0.081 13.0 4.2 0.18 11.9 4.2 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation TRPM_tetra PF16519.5 GBG67614.1 - 0.1 12.7 4.2 0.13 12.4 0.4 2.7 3 0 0 3 3 3 0 Tetramerisation domain of TRPM SKA1 PF07160.12 GBG67614.1 - 0.1 12.4 0.9 1.8 8.4 0.5 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Lzipper-MIP1 PF14389.6 GBG67614.1 - 0.12 12.7 0.2 0.39 11.1 0.2 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Trimer_CC PF08954.11 GBG67614.1 - 0.26 10.9 2.2 1 9.0 2.2 2.1 1 0 0 1 1 1 0 Trimerisation motif FUSC PF04632.12 GBG67614.1 - 2.1 6.8 5.5 3.8 5.9 5.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4448 PF14610.6 GBG67618.1 - 0.074 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SDA1 PF05285.12 GBG67618.1 - 0.48 9.8 11.8 0.54 9.6 11.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG67618.1 - 1.5 6.9 13.3 1.8 6.7 13.3 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG67618.1 - 1.7 6.8 11.9 2 6.6 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG67620.1 - 3.8e-27 94.2 0.0 9.9e-27 92.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67620.1 - 1.7e-25 89.4 0.0 4.7e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67620.1 - 3e-06 27.2 0.2 7e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67620.1 - 4.9e-05 23.0 0.1 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG67620.1 - 0.0052 17.0 8.1 0.1 12.9 0.0 4.1 5 1 0 5 5 5 2 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG67620.1 - 2.3 8.3 10.6 2.5 8.2 1.9 3.2 3 0 0 3 3 3 0 TolA binding protein trimerisation FAM216B PF15107.6 GBG67621.1 - 0.08 12.8 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 FAM216B protein family FAM199X PF15814.5 GBG67624.1 - 0.0057 15.8 6.5 0.014 14.5 6.5 1.6 1 0 0 1 1 1 1 Protein family FAM199X TilS PF09179.11 GBG67624.1 - 0.092 13.2 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 TilS substrate binding domain DUF515 PF04415.12 GBG67624.1 - 3.3 6.0 11.2 4.8 5.5 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Glyco_hydro_32N PF00251.20 GBG67627.1 - 2.4e-88 296.6 0.0 4.1e-88 295.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 GBG67627.1 - 1.2e-07 31.9 0.0 2.9e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal HEAT PF02985.22 GBG67627.1 - 4.4e-06 26.5 0.1 0.33 11.3 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 GBG67627.1 - 0.047 14.2 0.0 2.8 8.5 0.0 3.4 2 1 1 3 3 3 0 HEAT-like repeat Cnd1 PF12717.7 GBG67627.1 - 0.05 13.6 0.4 0.27 11.3 0.3 1.6 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DBP10CT PF08147.12 GBG67628.1 - 5.7e-12 45.7 1.9 5.7e-12 45.7 1.9 2.6 3 0 0 3 3 3 1 DBP10CT (NUC160) domain FAM176 PF14851.6 GBG67628.1 - 0.41 10.3 6.2 0.81 9.3 6.2 1.4 1 0 0 1 1 1 0 FAM176 family DUF501 PF04417.12 GBG67628.1 - 0.65 9.8 5.1 1.2 9.0 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) CDC45 PF02724.14 GBG67628.1 - 2.4 6.4 7.5 3.4 5.8 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 GBG67628.1 - 9.4 5.0 9.9 15 4.3 9.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF659 PF04937.15 GBG67629.1 - 5e-34 117.4 0.0 1.2e-33 116.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG67629.1 - 2.3e-06 27.3 0.1 5.4e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DEAD PF00270.29 GBG67630.1 - 1.5e-35 122.6 0.0 3.1e-35 121.5 0.0 1.5 2 0 0 2 2 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG67630.1 - 2.3e-25 89.1 0.0 2.3e-24 85.8 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2722 PF10846.8 GBG67630.1 - 1.2e-05 24.5 0.5 1.6e-05 24.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) NOA36 PF06524.12 GBG67630.1 - 0.00037 19.9 11.1 0.0006 19.2 11.1 1.3 1 0 0 1 1 1 1 NOA36 protein Cwf_Cwc_15 PF04889.12 GBG67630.1 - 0.00082 19.2 9.4 0.0014 18.4 9.4 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DsrH PF04077.12 GBG67630.1 - 0.022 14.9 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 DsrH like protein Sigma70_ner PF04546.13 GBG67630.1 - 0.032 14.1 4.0 0.062 13.2 4.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 GBG67630.1 - 0.045 13.4 0.5 0.094 12.4 0.5 1.5 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 GBG67630.1 - 0.046 13.2 3.6 0.068 12.6 3.6 1.3 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.11 GBG67630.1 - 0.071 13.1 5.7 0.13 12.3 5.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 GBG67630.1 - 0.11 10.7 12.1 0.14 10.3 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol3_chi PF04364.13 GBG67630.1 - 0.14 12.3 0.3 0.36 11.0 0.3 1.7 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC BUD22 PF09073.10 GBG67630.1 - 0.37 10.1 5.0 0.49 9.7 5.0 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 GBG67630.1 - 0.55 8.7 6.5 0.81 8.2 6.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 GBG67630.1 - 0.67 9.5 4.4 1.1 8.8 4.4 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GBG67630.1 - 0.94 7.5 16.7 1.4 6.9 16.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 GBG67630.1 - 1.7 7.7 23.8 2.8 7.0 23.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Utp14 PF04615.13 GBG67630.1 - 1.8 7.0 7.4 3.1 6.2 7.4 1.3 1 0 0 1 1 1 0 Utp14 protein YL1 PF05764.13 GBG67630.1 - 1.9 8.5 7.7 3.6 7.7 7.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein DUF2076 PF09849.9 GBG67630.1 - 3.7 7.5 9.0 5.6 6.9 9.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 GBG67630.1 - 4 7.3 8.5 6.2 6.7 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 GBG67630.1 - 6 6.4 10.0 9.7 5.7 10.0 1.2 1 0 0 1 1 1 0 PPP4R2 Tom22 PF04281.13 GBG67630.1 - 6.8 6.5 7.1 16 5.3 5.6 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Aldose_epim PF01263.20 GBG67631.1 - 2.6e-07 30.3 0.0 0.0048 16.2 0.0 2.3 2 0 0 2 2 2 2 Aldose 1-epimerase Ig_3 PF13927.6 GBG67632.1 - 0.072 13.7 0.8 15 6.3 0.0 3.0 1 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 GBG67632.1 - 0.094 12.8 0.1 36 4.5 0.0 3.0 1 1 1 3 3 3 0 Immunoglobulin I-set domain DUF1936 PF09151.10 GBG67632.1 - 0.51 10.3 14.5 5.3 7.0 1.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1936) Metallothio_Pro PF02069.16 GBG67632.1 - 7 7.0 15.5 2.3 8.5 1.4 3.3 3 0 0 3 3 3 0 Prokaryotic metallothionein DUF3492 PF11997.8 GBG67633.1 - 0.11 12.2 2.1 0.16 11.7 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) ubiquitin PF00240.23 GBG67634.1 - 4.1e-34 116.2 0.6 5.4e-34 115.8 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 GBG67634.1 - 1.7e-31 107.9 10.2 2.6e-31 107.2 10.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 GBG67634.1 - 1.7e-16 59.8 0.8 1.7e-16 59.8 0.8 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GBG67634.1 - 2.7e-05 24.6 0.1 0.00011 22.6 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GBG67634.1 - 0.0045 16.9 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain zf-C4pol PF14260.6 GBG67634.1 - 0.0072 16.8 0.8 0.013 16.0 0.8 1.3 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Ubiquitin_5 PF18037.1 GBG67634.1 - 0.0074 16.6 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GBG67634.1 - 0.0076 16.3 0.1 0.017 15.2 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GBG67634.1 - 0.017 15.7 0.1 0.019 15.5 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GBG67634.1 - 0.022 14.8 1.1 4.4 7.4 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain IL3Ra_N PF18611.1 GBG67635.1 - 0.067 13.2 3.4 0.24 11.4 0.1 2.3 1 1 1 2 2 2 0 IL-3 receptor alpha chain N-terminal domain RCC1 PF00415.18 GBG67637.1 - 1.2e-136 445.2 34.1 6e-15 55.6 0.2 13.5 13 0 0 13 13 13 12 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG67637.1 - 4.6e-92 300.4 54.8 8.8e-11 41.3 0.4 13.1 13 0 0 13 13 13 12 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 GBG67637.1 - 5.7 7.1 6.6 93 3.2 0.0 5.2 5 0 0 5 5 5 0 Kelch motif RCC1 PF00415.18 GBG67638.1 - 7.1e-154 500.4 35.8 6.3e-15 55.5 0.2 14.5 14 0 0 14 14 14 13 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG67638.1 - 4.5e-99 322.7 63.3 9.2e-11 41.3 0.4 14.4 14 0 0 14 14 14 13 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 GBG67638.1 - 0.39 10.4 1.4 46 3.6 0.0 4.7 6 0 0 6 6 6 0 TUP1-like enhancer of split Kelch_2 PF07646.15 GBG67638.1 - 5.5 7.1 6.3 97 3.2 0.0 5.1 5 0 0 5 5 5 0 Kelch motif RVT_1 PF00078.27 GBG67639.1 - 1.8e-31 109.4 0.1 3.4e-31 108.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos PF00149.28 GBG67639.1 - 5.3e-07 30.3 3.1 1e-06 29.4 3.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Asp_protease_2 PF13650.6 GBG67639.1 - 0.0068 17.0 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG67639.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG67639.1 - 0.16 12.5 0.0 0.42 11.2 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4407 PF14362.6 GBG67639.1 - 6.5 6.0 9.2 15 4.8 9.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myb_DNA-bind_4 PF13837.6 GBG67640.1 - 0.0038 17.6 0.5 0.0079 16.6 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG67641.1 - 6.4e-29 101.1 0.1 2e-28 99.4 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67641.1 - 5.9e-16 58.3 0.0 2.3e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67641.1 - 2e-08 34.5 0.0 7.9e-08 32.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG67641.1 - 0.05 13.9 0.0 0.21 11.9 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein Chloroa_b-bind PF00504.21 GBG67642.1 - 0.022 15.3 0.1 0.035 14.6 0.1 1.3 1 0 0 1 1 1 0 Chlorophyll A-B binding protein RVT_1 PF00078.27 GBG67643.1 - 1.4e-33 116.3 0.1 2.4e-33 115.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67643.1 - 1.8e-22 79.2 0.0 7.5e-22 77.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67643.1 - 4.3e-11 43.0 0.0 1.6e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Muted PF14942.6 GBG67643.1 - 0.21 11.9 11.8 0.16 12.3 8.1 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF4392 PF14336.6 GBG67643.1 - 0.21 11.0 0.2 0.65 9.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Arc_PepC_II PF06847.11 GBG67643.1 - 0.45 11.1 4.0 1.1e+02 3.5 3.0 3.8 4 0 0 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II Erythro_esteras PF05139.14 GBG67643.1 - 1.3 8.8 6.2 1.6 8.5 5.1 1.6 2 0 0 2 2 2 0 Erythromycin esterase Bestrophin PF01062.21 GBG67644.1 - 2e-26 93.1 0.5 1.1e-25 90.6 0.5 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DDE_Tnp_4 PF13359.6 GBG67645.1 - 9.6e-28 96.8 0.0 1.6e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67645.1 - 1.5e-11 44.3 0.0 2.8e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein CDC45 PF02724.14 GBG67645.1 - 0.49 8.6 11.6 0.68 8.1 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG67645.1 - 0.81 9.1 4.7 1.2 8.5 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 GBG67645.1 - 6.7 6.0 16.4 11 5.4 16.4 1.2 1 0 0 1 1 1 0 SDA1 Myb_DNA-bind_4 PF13837.6 GBG67646.1 - 2.2e-11 44.0 2.7 5.1e-11 42.8 2.7 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67646.1 - 0.00011 22.4 1.4 0.00028 21.1 1.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG67646.1 - 4.1 7.6 7.7 0.33 11.0 2.2 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Aconitase PF00330.20 GBG67648.1 - 3.8e-150 500.9 0.0 7e-91 305.5 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GBG67648.1 - 1.2e-43 148.6 0.0 2.8e-43 147.4 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain RT_RNaseH_2 PF17919.1 GBG67648.1 - 2.8e-27 94.7 0.0 5e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67648.1 - 4.4e-24 84.8 0.0 8.6e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67648.1 - 1.8e-07 30.9 0.0 2.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) E3_UFM1_ligase PF09743.9 GBG67649.1 - 4.2e-85 285.7 0.0 6.4e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 FeoC PF09012.10 GBG67649.1 - 0.0028 17.7 0.1 0.38 10.9 0.0 2.7 2 0 0 2 2 2 2 FeoC like transcriptional regulator WD40 PF00400.32 GBG67650.1 - 1.5e-21 76.3 23.7 0.0012 19.6 0.2 6.5 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG67650.1 - 1.2e-06 28.7 9.5 0.056 13.8 0.3 4.4 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Fibrillarin PF01269.17 GBG67650.1 - 0.058 12.5 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin IKI3 PF04762.12 GBG67650.1 - 0.17 9.8 0.5 0.59 8.1 0.0 1.8 2 0 0 2 2 2 0 IKI3 family Pkinase_Tyr PF07714.17 GBG67651.1 - 3e-31 108.6 0.0 5.3e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG67651.1 - 8.8e-28 97.4 0.0 1.4e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 GBG67651.1 - 4.8e-20 71.3 8.6 3.5e-05 24.1 0.1 5.8 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG67651.1 - 2.6e-17 62.3 19.1 1e-06 28.4 0.1 5.0 4 1 1 5 5 5 4 Leucine rich repeat DUF659 PF04937.15 GBG67651.1 - 8.1e-15 55.0 0.0 1.7e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) LRRNT_2 PF08263.12 GBG67651.1 - 4.2e-12 46.2 2.6 5.2e-06 26.7 0.2 2.9 2 0 0 2 2 2 2 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GBG67651.1 - 2.4e-08 33.4 9.5 2.6 8.9 0.0 7.9 6 1 1 7 7 7 2 Leucine Rich Repeat GLTT PF01744.20 GBG67651.1 - 0.00039 20.1 0.3 0.035 13.8 0.0 3.5 3 0 0 3 3 3 1 GLTT repeat (6 copies) LRR_6 PF13516.6 GBG67651.1 - 0.004 17.1 12.5 4.7 7.5 0.1 6.3 6 0 0 6 6 6 2 Leucine Rich repeat Rubis-subs-bind PF09273.11 GBG67652.1 - 5.7e-22 78.8 0.0 5.7e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding RVT_1 PF00078.27 GBG67653.1 - 7e-70 235.0 0.6 2.1e-28 99.4 0.0 3.3 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67653.1 - 7.4e-68 224.9 0.2 3.9e-23 81.4 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67653.1 - 1.5e-33 114.7 2.1 1.5e-15 57.0 0.2 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG67653.1 - 8e-33 112.9 0.0 5.9e-11 42.6 0.0 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Pkinase_Tyr PF07714.17 GBG67653.1 - 8.3e-23 81.0 0.0 7.8e-14 51.6 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG67653.1 - 8.9e-20 71.1 0.0 2.1e-15 56.8 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain rve PF00665.26 GBG67653.1 - 1.3e-19 70.5 2.9 2.2e-08 34.3 0.0 3.5 4 0 0 4 4 4 2 Integrase core domain RVP_2 PF08284.11 GBG67653.1 - 6e-05 22.8 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67653.1 - 0.06 14.0 0.0 0.19 12.4 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease FAM60A PF15396.6 GBG67654.1 - 0.39 10.7 6.0 0.52 10.3 6.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.14 GBG67654.1 - 2.1 6.6 20.0 2.3 6.4 20.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GBG67654.1 - 3.2 6.1 23.1 3.8 5.8 23.1 1.2 1 0 0 1 1 1 0 Mpp10 protein NPR3 PF03666.13 GBG67654.1 - 3.5 6.3 19.6 4.2 6.1 19.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 GBG67654.1 - 3.6 6.5 14.0 4 6.3 14.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Nop14 PF04147.12 GBG67654.1 - 3.9 5.6 25.5 4.6 5.3 25.5 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG67654.1 - 4.6 5.9 16.2 5.2 5.7 16.2 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 GBG67654.1 - 4.6 5.9 8.7 6.2 5.5 8.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 GBG67654.1 - 7 6.6 5.7 8.1 6.4 5.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sel1 PF08238.12 GBG67655.1 - 0.00023 21.7 1.6 0.12 13.1 0.0 4.6 5 0 0 5 5 5 1 Sel1 repeat RNA_polI_A34 PF08208.11 GBG67655.1 - 0.054 13.6 0.6 0.054 13.6 0.6 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 AA_permease_2 PF13520.6 GBG67656.1 - 0.00034 19.6 5.3 0.00048 19.1 5.3 1.2 1 0 0 1 1 1 1 Amino acid permease SUR7 PF06687.12 GBG67656.1 - 0.034 13.8 1.5 0.056 13.1 1.5 1.4 1 0 0 1 1 1 0 SUR7/PalI family DUF4013 PF13197.6 GBG67656.1 - 0.24 11.2 13.9 0.36 10.7 13.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) LMF1 PF06762.14 GBG67656.1 - 0.28 10.2 0.6 0.29 10.2 0.6 1.1 1 0 0 1 1 1 0 Lipase maturation factor UPF0182 PF03699.13 GBG67656.1 - 1.3 7.0 4.1 1.4 7.0 4.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF898 PF05987.13 GBG67656.1 - 2.4 7.1 14.0 1 8.4 12.0 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF1616 PF07760.11 GBG67656.1 - 2.6 7.3 9.4 5.1 6.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DUF2207 PF09972.9 GBG67656.1 - 5.7 5.6 4.5 7.4 5.2 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4577 PF15145.6 GBG67656.1 - 10 6.2 10.5 5.7 7.0 3.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) Pkinase PF00069.25 GBG67658.1 - 4.9e-69 232.6 0.0 7.5e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG67658.1 - 1.8e-30 106.1 0.0 2.7e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG67658.1 - 3.1e-05 23.5 0.2 0.00032 20.1 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 GBG67658.1 - 0.047 12.6 0.0 2.7 6.9 0.0 2.1 1 1 1 2 2 2 0 Haspin like kinase domain RVT_1 PF00078.27 GBG67660.1 - 1.3e-33 116.4 0.1 2.1e-33 115.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67660.1 - 2e-29 101.6 0.0 4.4e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67660.1 - 3.5e-27 94.7 0.1 6.3e-27 93.9 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rhamno_transf PF11316.8 GBG67660.1 - 0.0059 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative rhamnosyl transferase TMEM52 PF14979.6 GBG67660.1 - 0.046 13.7 0.2 0.093 12.6 0.2 1.4 1 0 0 1 1 1 0 Transmembrane 52 Snf7 PF03357.21 GBG67661.1 - 2.2e-10 40.4 16.2 2.3e-09 37.1 9.4 1.9 1 1 1 2 2 2 2 Snf7 Ist1 PF03398.14 GBG67661.1 - 2.9e-05 24.1 3.5 4.1e-05 23.6 3.5 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ABC_sub_bind PF04392.12 GBG67661.1 - 0.036 13.3 0.2 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 ABC transporter substrate binding protein DMSP_lyase PF16867.5 GBG67661.1 - 0.081 12.6 0.3 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase Seryl_tRNA_N PF02403.22 GBG67661.1 - 0.62 10.3 13.5 0.21 11.8 0.9 3.2 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TBCA PF02970.16 GBG67661.1 - 9.5 6.6 10.0 1.8 8.9 2.3 3.0 2 2 1 3 3 3 0 Tubulin binding cofactor A LRR_6 PF13516.6 GBG67663.1 - 1.5e-17 62.1 15.9 0.00017 21.4 0.0 8.6 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 GBG67663.1 - 4e-10 39.8 3.9 0.0043 17.4 0.1 5.3 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG67663.1 - 1.8e-08 34.1 0.0 5.4e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 GBG67663.1 - 0.00016 21.8 19.3 4.4 8.2 0.0 8.7 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.6 GBG67663.1 - 0.0006 19.5 0.1 0.54 10.1 0.0 3.9 3 1 1 4 4 4 1 Leucine rich repeat F-box-like PF12937.7 GBG67663.1 - 0.00061 19.6 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like Adaptin_N PF01602.20 GBG67668.1 - 1.7e-101 340.4 0.1 2.5e-84 283.7 0.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 GBG67668.1 - 5.4e-14 52.6 0.1 8.7e-13 48.6 0.0 2.7 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 GBG67668.1 - 1.6e-13 51.2 0.0 3.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 GBG67668.1 - 6e-11 42.6 4.4 1.4e-06 28.5 0.3 3.4 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 GBG67668.1 - 1.1e-05 25.3 5.1 1.3 9.5 0.1 4.7 4 0 0 4 4 4 3 HEAT repeat Cohesin_HEAT PF12765.7 GBG67668.1 - 0.00039 20.7 1.2 0.21 11.9 0.1 2.7 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion SpoIIP PF07454.11 GBG67668.1 - 5.8 6.3 11.4 11 5.4 11.4 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PI3K_1B_p101 PF10486.9 GBG67668.1 - 6.5 4.4 6.5 11 3.6 6.5 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Iso_dh PF00180.20 GBG67669.1 - 4e-86 289.3 0.0 4.8e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SCO1-SenC PF02630.14 GBG67670.1 - 1.7e-50 170.4 0.2 2.3e-50 170.0 0.2 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 GBG67670.1 - 2.6e-06 27.4 0.0 4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family FixQ PF05545.11 GBG67670.1 - 0.03 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Ndc1_Nup PF09531.10 GBG67670.1 - 0.31 9.7 0.5 0.42 9.2 0.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup COPR5 PF15340.6 GBG67670.1 - 0.55 10.9 3.3 18 5.9 0.0 2.2 2 0 0 2 2 2 0 Cooperator of PRMT5 family Apt1 PF10351.9 GBG67670.1 - 1.5 7.6 6.0 2.1 7.1 6.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 GBG67670.1 - 2.1 7.5 8.7 2.6 7.2 8.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RVT_1 PF00078.27 GBG67671.1 - 1.1e-31 110.2 0.0 1.9e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C2 PF00168.30 GBG67671.1 - 9.1e-23 80.5 0.0 1.9e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain RT_RNaseH PF17917.1 GBG67671.1 - 2.8e-20 72.6 0.1 7.2e-20 71.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67671.1 - 2.4e-11 43.5 0.0 6.7e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG67671.1 - 7.6e-07 29.0 0.0 2.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67671.1 - 0.00069 20.2 0.0 0.0021 18.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67671.1 - 0.0023 18.5 0.0 0.0067 17.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG67671.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) AMIN PF11741.8 GBG67671.1 - 0.084 13.0 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 AMIN domain DUF1564 PF07600.11 GBG67672.1 - 0.0049 16.6 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG67672.1 - 0.033 14.4 0.1 0.23 11.8 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein HHH_9 PF17674.1 GBG67672.1 - 0.1 13.5 2.7 8 7.5 1.0 3.2 1 1 1 2 2 2 0 HHH domain Pex14_N PF04695.13 GBG67672.1 - 1.9 9.2 8.7 0.52 11.0 0.6 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I_N PF18670.1 GBG67673.1 - 0.021 15.2 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain Glyco_transf_34 PF05637.12 GBG67674.1 - 4.1e-14 52.9 0.0 7.1e-13 48.8 0.0 2.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ATPgrasp_N PF18130.1 GBG67674.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp N-terminal domain Rad60-SLD_2 PF13881.6 GBG67675.1 - 3.5e-35 120.5 0.0 4.1e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GBG67675.1 - 8.3e-05 22.3 0.0 0.00021 20.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 GBG67675.1 - 0.12 13.0 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF569 PF04601.13 GBG67677.1 - 0.53 10.0 16.7 7.6 6.2 0.3 7.5 7 1 1 8 8 8 0 Domain of unknown function (DUF569) Peptidase_Prp PF04327.12 GBG67677.1 - 1.2 9.4 14.0 11 6.3 0.0 7.4 4 2 2 6 6 6 0 Cysteine protease Prp Nudix_hydro PF18290.1 GBG67677.1 - 1.6 8.8 4.5 4.1 7.5 1.9 3.3 2 0 0 2 2 2 0 Nudix hydrolase domain RT_RNaseH_2 PF17919.1 GBG67678.1 - 1.6e-23 82.6 0.0 6.3e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67678.1 - 2.1e-20 73.0 0.0 7.9e-20 71.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67678.1 - 3.4e-18 65.5 0.3 6.4e-18 64.6 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67678.1 - 0.00023 20.8 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG67678.1 - 0.0076 16.5 0.1 0.04 14.2 0.1 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein IL22 PF14565.6 GBG67678.1 - 0.029 14.7 0.1 0.67 10.2 0.0 2.4 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor SlyX PF04102.12 GBG67678.1 - 0.04 14.5 0.2 0.04 14.5 0.2 3.5 4 0 0 4 4 4 0 SlyX IL22 PF14565.6 GBG67679.1 - 0.0018 18.5 0.1 0.11 12.8 0.0 2.2 2 0 0 2 2 2 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor Retrotrans_gag PF03732.17 GBG67679.1 - 0.0026 18.0 0.4 0.012 15.9 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein SlyX PF04102.12 GBG67679.1 - 0.0094 16.5 0.2 0.0094 16.5 0.2 3.2 3 1 0 3 3 3 1 SlyX RVT_1 PF00078.27 GBG67681.1 - 3.3e-26 92.2 0.1 5.5e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67681.1 - 2.6e-13 49.9 0.0 7.2e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG67681.1 - 7.9e-06 26.4 0.0 2.1e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG67681.1 - 2.2e-05 24.6 0.0 6.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG67681.1 - 6.7e-05 23.5 0.0 0.00019 22.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG67681.1 - 0.00013 22.0 1.0 0.0004 20.4 1.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG67681.1 - 0.00024 21.3 0.0 0.00065 20.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG67681.1 - 0.00041 20.1 0.0 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67681.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease ApoLp-III PF07464.11 GBG67681.1 - 0.2 11.7 0.1 0.43 10.7 0.1 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) RT_RNaseH_2 PF17919.1 GBG67682.1 - 2.4e-19 69.2 0.0 6.7e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67682.1 - 1.1e-10 41.8 0.0 3.5e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67682.1 - 1.4e-09 38.1 0.4 3.8e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG67682.1 - 0.00058 19.4 0.2 0.0023 17.5 0.1 2.1 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG67682.1 - 0.038 14.3 0.1 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein Homeobox_KN PF05920.11 GBG67684.1 - 0.037 13.9 0.2 0.086 12.8 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain LINES_N PF14694.6 GBG67685.1 - 0.27 10.7 2.7 0.58 9.6 2.7 1.5 1 0 0 1 1 1 0 Lines N-terminus LINES_N PF14694.6 GBG67686.1 - 0.3 10.5 2.9 0.66 9.4 2.9 1.5 1 0 0 1 1 1 0 Lines N-terminus DDE_Tnp_IS1595 PF12762.7 GBG67687.1 - 0.42 10.6 3.4 0.36 10.8 0.3 2.4 2 0 0 2 2 2 0 ISXO2-like transposase domain K_channel_TID PF07941.11 GBG67687.1 - 5.2 7.6 22.6 2.7 8.5 19.0 2.5 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Cornifin PF02389.15 GBG67687.1 - 5.3 7.2 42.9 1.5 9.0 23.4 3.8 2 1 1 3 3 3 0 Cornifin (SPRR) family eIF3_subunit PF08597.10 GBG67688.1 - 0.023 14.6 9.0 0.03 14.2 9.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TarH PF02203.15 GBG67688.1 - 0.025 14.5 3.0 0.033 14.1 3.0 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue TMEM51 PF15345.6 GBG67688.1 - 0.026 14.3 0.6 0.043 13.7 0.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DDRGK PF09756.9 GBG67688.1 - 0.029 14.0 9.5 0.045 13.4 9.5 1.3 1 0 0 1 1 1 0 DDRGK domain AIF_C PF14721.6 GBG67688.1 - 0.14 12.5 0.5 0.21 11.9 0.5 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term GRIM-19 PF06212.12 GBG67688.1 - 2.1 8.3 4.5 3.2 7.7 4.5 1.2 1 0 0 1 1 1 0 GRIM-19 protein V_ATPase_I PF01496.19 GBG67688.1 - 3.3 5.5 3.7 4.2 5.2 3.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Radial_spoke_3 PF06098.11 GBG67688.1 - 4.4 6.5 15.0 7.5 5.7 15.0 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 Trehalose_PPase PF02358.16 GBG67690.1 - 9e-66 221.3 0.0 3.3e-65 219.5 0.0 1.8 1 1 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 GBG67690.1 - 0.016 14.9 0.0 0.21 11.3 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GBG67690.1 - 0.031 13.8 0.0 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase PRAP PF15314.6 GBG67690.1 - 0.58 10.7 3.7 1.6 9.3 3.7 1.7 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine KAR9 PF08580.10 GBG67691.1 - 0.72 8.3 1.6 0.95 7.9 1.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Myb_DNA-bind_4 PF13837.6 GBG67692.1 - 3.7e-08 33.7 3.9 8e-08 32.6 3.9 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG67692.1 - 0.17 11.9 4.3 0.39 10.8 4.3 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG67693.1 - 3.5e-23 82.0 0.0 2.9e-22 79.0 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67693.1 - 4.6e-12 46.0 0.0 8.7e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67693.1 - 0.018 14.7 0.5 2 8.0 0.0 2.5 2 1 0 2 2 2 0 Transposase DDE domain BUD22 PF09073.10 GBG67694.1 - 0.21 10.9 26.1 0.28 10.5 26.1 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG67694.1 - 0.31 10.4 22.6 0.38 10.1 22.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG67694.1 - 0.53 8.5 16.5 0.7 8.1 16.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GBG67694.1 - 0.61 8.8 6.2 0.72 8.6 6.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG67694.1 - 0.68 8.1 23.9 0.9 7.7 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family DREPP PF05558.12 GBG67694.1 - 0.89 9.4 19.6 1.3 8.8 19.6 1.4 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DUF4746 PF15928.5 GBG67694.1 - 1.8 7.9 15.6 2.5 7.4 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Cwf_Cwc_15 PF04889.12 GBG67694.1 - 1.9 8.1 20.0 2.8 7.6 20.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 GBG67694.1 - 2.3 7.7 17.8 3.7 7.0 17.8 1.3 1 0 0 1 1 1 0 PPP4R2 Zip PF02535.22 GBG67694.1 - 3.2 6.9 3.8 4.3 6.5 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIIAH PF12685.7 GBG67694.1 - 3.4 7.5 13.9 5 6.9 13.9 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein YL1 PF05764.13 GBG67694.1 - 3.7 7.6 26.6 5.2 7.1 26.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SURF2 PF05477.11 GBG67694.1 - 6.1 6.5 12.1 8.9 5.9 12.1 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF913 PF06025.12 GBG67694.1 - 6.5 5.6 5.6 8.1 5.3 5.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 GBG67694.1 - 9.5 6.0 14.9 14 5.4 14.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RT_RNaseH_2 PF17919.1 GBG67695.1 - 9e-27 93.0 0.0 1.5e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67695.1 - 2e-22 79.4 0.0 5.5e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67695.1 - 1.8e-07 30.9 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG67695.1 - 0.13 10.5 7.7 0.16 10.1 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG67696.1 - 2.8e-23 81.8 0.0 1.8e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67696.1 - 1.1e-21 77.1 0.0 3.1e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67696.1 - 2.4e-10 40.3 0.2 1.4e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67696.1 - 4.8e-09 36.4 0.3 3.1e-08 33.8 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain WTX PF09422.10 GBG67696.1 - 0.052 12.6 2.5 0.082 12.0 2.5 1.2 1 0 0 1 1 1 0 WTX protein RT_RNaseH_2 PF17919.1 GBG67697.1 - 3.2e-25 88.1 0.0 8e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67697.1 - 6.4e-23 81.0 0.1 2.7e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67697.1 - 8.9e-09 35.2 0.1 1.7e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67697.1 - 2.5e-06 27.7 0.1 1.7e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG67697.1 - 0.0009 19.1 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG67697.1 - 0.0012 19.1 2.5 0.002 18.4 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein AIP3 PF03915.13 GBG67697.1 - 0.12 11.4 4.7 0.22 10.6 4.7 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Etmic-2 PF06670.11 GBG67697.1 - 0.22 10.4 4.0 0.35 9.7 4.0 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 Exo_endo_phos PF03372.23 GBG67698.1 - 0.003 17.1 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG67698.1 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 GBG67699.1 - 0.0051 16.4 0.1 0.45 10.0 0.1 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fez1 PF06818.15 GBG67699.1 - 0.026 15.0 16.0 0.12 12.9 8.0 2.3 2 0 0 2 2 2 0 Fez1 HOOK PF05622.12 GBG67699.1 - 0.47 8.5 14.6 0.011 13.9 7.5 1.7 2 0 0 2 2 2 0 HOOK protein NYD-SP28_assoc PF14775.6 GBG67699.1 - 1.9 8.7 5.4 1.9 8.6 2.1 2.6 1 1 1 2 2 2 0 Sperm tail C-terminal domain YabA PF06156.13 GBG67699.1 - 4.4 8.0 6.1 34 5.1 6.2 2.5 1 1 0 1 1 1 0 Initiation control protein YabA HTH_Tnp_1 PF01527.20 GBG67699.1 - 5.6 7.4 7.1 2.6 8.4 1.4 3.0 2 1 0 2 2 2 0 Transposase DivIC PF04977.15 GBG67700.1 - 0.018 14.8 0.2 0.018 14.8 0.2 5.1 4 1 1 5 5 5 0 Septum formation initiator Lectin_N PF03954.14 GBG67700.1 - 0.046 13.5 4.0 3.2 7.5 0.0 2.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain FlaC_arch PF05377.11 GBG67700.1 - 1.1 9.7 6.0 2 8.9 0.2 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4156 PF13698.6 GBG67700.1 - 1.4 9.3 4.2 2.6 8.4 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4156) Abhydrolase_1 PF00561.20 GBG67701.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4774 PF15999.5 GBG67701.1 - 1.8 8.4 5.3 3.3 7.6 2.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4774) MIT_LIKE_ACTX PF17556.2 GBG67702.1 - 0.078 13.6 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 MIT-like atracotoxin family RT_RNaseH_2 PF17919.1 GBG67703.1 - 1.3e-23 82.9 0.0 5e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67703.1 - 1.6e-23 83.0 0.0 1e-22 80.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67703.1 - 9.9e-20 70.4 0.2 2e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG67703.1 - 1.8e-07 31.7 0.0 4.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67703.1 - 5.3e-06 26.9 0.0 1.5e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67703.1 - 7e-06 25.9 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG67703.1 - 0.001 19.3 0.2 0.0053 17.0 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG67703.1 - 0.0034 17.2 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG67703.1 - 0.016 14.7 0.1 0.14 11.6 0.0 2.5 2 1 1 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) Fez1 PF06818.15 GBG67703.1 - 0.048 14.1 0.2 0.048 14.1 0.2 2.5 2 0 0 2 2 2 0 Fez1 zf-H2C2 PF09337.10 GBG67703.1 - 0.093 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger IL28A PF15177.6 GBG67703.1 - 0.37 10.6 5.6 1 9.2 5.6 1.7 1 0 0 1 1 1 0 Interleukin-28A TolA_bind_tri PF16331.5 GBG67703.1 - 0.38 10.9 5.0 1 9.5 5.0 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation tRNA-synt_1g PF09334.11 GBG67705.1 - 1.9e-98 329.8 0.2 4.1e-61 206.9 0.0 2.9 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GBG67705.1 - 3.8e-26 91.5 0.0 2e-11 42.9 0.0 3.1 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 GBG67705.1 - 4e-06 26.4 0.0 0.0087 15.4 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 GBG67705.1 - 0.00014 21.9 0.2 0.00047 20.2 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA RT_RNaseH_2 PF17919.1 GBG67706.1 - 7.3e-30 103.0 0.0 2.1e-29 101.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67706.1 - 2.3e-24 85.7 0.0 5.7e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67706.1 - 1.9e-14 53.7 0.3 2.8e-13 49.9 0.1 2.3 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIT_CC PF16559.5 GBG67706.1 - 0.14 12.0 1.2 0.46 10.4 1.2 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-CCHC PF00098.23 GBG67708.1 - 1.4e-10 40.7 9.1 2.1e-07 30.7 3.2 3.0 2 0 0 2 2 2 2 Zinc knuckle gag-asp_proteas PF13975.6 GBG67708.1 - 2.7e-08 34.3 0.2 1.5e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67708.1 - 1e-06 29.3 0.1 4e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG67708.1 - 0.0033 17.2 0.3 0.0065 16.3 0.3 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_6 PF15288.6 GBG67708.1 - 0.053 13.4 5.5 1.5 8.7 0.9 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG67708.1 - 0.071 12.9 2.7 1.3 8.8 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG67708.1 - 0.072 13.1 0.7 0.3 11.1 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 GBG67708.1 - 0.17 11.6 0.4 0.44 10.3 0.4 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 GBG67708.1 - 5.6 6.9 11.7 0.065 13.1 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle DUF4140 PF13600.6 GBG67709.1 - 0.033 14.6 0.8 0.033 14.6 0.8 2.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 GBG67709.1 - 0.035 13.4 2.3 0.047 13.0 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2514 PF10721.9 GBG67709.1 - 0.11 12.5 3.9 0.13 12.3 1.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2514) HR1 PF02185.16 GBG67709.1 - 1.2 9.2 8.3 0.28 11.3 2.3 2.5 2 0 0 2 2 2 0 Hr1 repeat Wtap PF17098.5 GBG67709.1 - 4.1 7.3 12.3 0.25 11.3 1.5 2.6 1 1 2 3 3 3 0 WTAP/Mum2p family Shugoshin_N PF07558.11 GBG67709.1 - 6.3 6.8 12.2 4.6 7.2 1.9 4.1 4 1 1 5 5 5 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 GBG67709.1 - 7.6 6.4 10.0 2 8.2 2.4 2.9 3 1 0 3 3 3 0 Septum formation initiator zf-CCHC PF00098.23 GBG67711.1 - 7.5e-07 29.0 3.2 7.5e-07 29.0 3.2 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG67711.1 - 0.17 11.7 3.9 0.36 10.7 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG67711.1 - 0.21 11.3 0.4 0.41 10.4 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle AP2 PF00847.20 GBG67712.1 - 3.2e-13 49.7 1.7 6.9e-13 48.6 1.7 1.6 1 0 0 1 1 1 1 AP2 domain RNA_pol_3_Rpc31 PF11705.8 GBG67712.1 - 0.0032 17.7 8.1 0.0032 17.7 8.1 3.4 3 0 0 3 3 3 2 DNA-directed RNA polymerase III subunit Rpc31 Co_AT_N PF12557.8 GBG67713.1 - 0.16 12.0 5.0 0.44 10.5 5.0 1.8 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal DUF659 PF04937.15 GBG67714.1 - 4e-33 114.4 0.1 6.1e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG67714.1 - 4.2e-05 23.3 0.4 8.8e-05 22.2 0.4 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RAB3GAP2_C PF14656.6 GBG67717.1 - 0.002 16.5 3.0 0.0023 16.3 3.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus Astro_capsid_p PF12226.8 GBG67717.1 - 0.023 13.9 15.8 0.032 13.4 15.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CPSF100_C PF13299.6 GBG67717.1 - 0.026 14.7 8.9 0.049 13.8 8.9 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BUD22 PF09073.10 GBG67717.1 - 0.027 13.8 30.8 0.034 13.5 30.8 1.1 1 0 0 1 1 1 0 BUD22 Serinc PF03348.15 GBG67717.1 - 0.37 9.6 1.6 0.53 9.1 1.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SpoIIIAH PF12685.7 GBG67717.1 - 0.39 10.5 18.0 0.58 10.0 18.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 GBG67717.1 - 0.41 8.8 31.4 0.51 8.5 31.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG67717.1 - 0.57 9.6 32.8 0.72 9.2 32.8 1.1 1 0 0 1 1 1 0 SDA1 Autophagy_N PF03986.13 GBG67717.1 - 1.1 9.1 12.4 0.83 9.6 10.9 1.5 1 1 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain CDC45 PF02724.14 GBG67717.1 - 1.6 6.9 22.2 2 6.6 22.2 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG67717.1 - 1.8 7.8 22.3 2.9 7.1 22.3 1.3 1 0 0 1 1 1 0 NOA36 protein NPR3 PF03666.13 GBG67717.1 - 3.4 6.3 11.0 4.3 6.0 11.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TRAP_alpha PF03896.16 GBG67717.1 - 4.9 6.3 14.7 8.2 5.5 14.7 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPL5 PF18168.1 GBG67717.1 - 6.2 6.0 10.0 8.3 5.6 10.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DNA_pol_phi PF04931.13 GBG67717.1 - 6.8 4.6 35.1 8.9 4.3 35.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Plasmodium_Vir PF05795.11 GBG67717.1 - 8.9 5.6 9.2 11 5.3 9.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Zip PF02535.22 GBG67717.1 - 8.9 5.4 8.9 11 5.1 8.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SURF2 PF05477.11 GBG67717.1 - 9.7 5.8 16.1 14 5.3 16.1 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) gag-asp_proteas PF13975.6 GBG67719.1 - 5.4e-05 23.7 0.0 0.00027 21.4 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67719.1 - 0.00044 20.8 0.0 0.0014 19.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG67719.1 - 0.0027 17.5 0.2 0.0051 16.6 0.2 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Hint_2 PF13403.6 GBG67719.1 - 0.0086 16.4 1.5 0.21 11.9 0.3 2.5 2 0 0 2 2 2 1 Hint domain Nop14 PF04147.12 GBG67720.1 - 0.025 12.8 7.3 0.028 12.7 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG67720.1 - 0.18 10.1 9.3 0.22 9.8 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG67720.1 - 0.55 9.6 11.2 0.75 9.2 11.2 1.2 1 0 0 1 1 1 0 SDA1 SIR4_SID PF16991.5 GBG67720.1 - 6.3 6.8 7.5 9.2 6.3 7.5 1.2 1 0 0 1 1 1 0 Sir4 SID domain RT_RNaseH_2 PF17919.1 GBG67721.1 - 8.4e-26 89.9 0.0 1.4e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67721.1 - 5.3e-23 81.3 0.0 1.1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67721.1 - 2.8e-06 27.0 0.1 6.2e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTPRCAP PF15713.5 GBG67721.1 - 0.18 12.1 7.9 0.32 11.3 7.9 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF3221 PF11518.8 GBG67721.1 - 0.48 10.8 7.0 2.7 8.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3221) CDC45 PF02724.14 GBG67721.1 - 0.96 7.7 4.8 1.3 7.2 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG67721.1 - 3.8 5.6 8.5 5.1 5.2 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family BAF1_ABF1 PF04684.13 GBG67722.1 - 0.21 10.6 27.4 0.81 8.7 14.7 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Utp14 PF04615.13 GBG67722.1 - 4.9 5.6 12.5 6.3 5.2 12.5 1.2 1 0 0 1 1 1 0 Utp14 protein Myb_DNA-bind_4 PF13837.6 GBG67723.1 - 1.2e-12 48.0 1.8 2.9e-12 46.8 1.8 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF3693 PF12472.8 GBG67723.1 - 0.0049 16.5 1.1 0.033 13.9 0.5 2.5 2 0 0 2 2 2 1 Phage related protein Myb_DNA-bind_6 PF13921.6 GBG67723.1 - 0.0069 16.6 0.2 0.021 15.1 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67723.1 - 0.0085 16.4 0.8 0.025 14.9 0.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG67723.1 - 0.016 15.2 2.2 0.037 14.1 2.2 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 GBG67723.1 - 0.019 16.0 0.2 0.047 14.7 0.2 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG67723.1 - 0.071 13.3 1.2 0.23 11.7 0.4 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain FSAP_sig_propep PF03032.15 GBG67724.1 - 1.6 8.9 5.2 0.83 9.7 0.6 2.2 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide Menin PF05053.13 GBG67726.1 - 1.1 7.5 7.5 1.4 7.2 7.5 1.1 1 0 0 1 1 1 0 Menin Myb_DNA-binding PF00249.31 GBG67727.1 - 2.3e-14 53.3 0.8 3.6e-14 52.7 0.8 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GBG67727.1 - 0.0012 18.7 0.5 0.0018 18.1 0.5 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 GBG67727.1 - 0.0065 16.7 0.9 0.01 16.1 0.9 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain JHY PF15261.6 GBG67727.1 - 0.79 10.4 7.8 0.41 11.3 0.4 2.1 1 1 1 2 2 2 0 Jhy protein RT_RNaseH_2 PF17919.1 GBG67728.1 - 1.3e-24 86.1 0.0 2.3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67728.1 - 4.4e-22 78.4 0.0 9.2e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67728.1 - 3.8e-16 59.3 0.0 5.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG67728.1 - 1.3 8.4 28.6 2.8 7.3 11.3 2.1 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 GBG67728.1 - 2.1 6.5 26.5 1.6 6.9 8.4 2.1 2 0 0 2 2 2 0 CDC45-like protein PTPRCAP PF15713.5 GBG67728.1 - 3.1 8.1 37.5 0.58 10.4 10.5 2.7 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GBG67728.1 - 10 4.2 27.4 1.1 7.5 5.7 2.1 2 0 0 2 2 2 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG67729.1 - 7.6e-25 86.9 0.0 1.4e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67729.1 - 2.4e-22 79.2 0.0 5.5e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67729.1 - 3.7e-10 39.7 0.0 5.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG67729.1 - 0.46 9.8 10.0 0.63 9.4 10.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG67729.1 - 2.1 6.6 10.3 2.7 6.2 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG67730.1 - 3.8e-25 87.8 0.0 6.7e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67730.1 - 1e-22 80.4 0.0 2.7e-22 79.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67730.1 - 1.9e-10 40.6 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG67731.1 - 5.3e-50 170.2 0.0 6.9e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG67731.1 - 5.9e-17 61.8 0.1 8.7e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG67731.1 - 0.0004 20.4 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GBG67731.1 - 0.055 13.0 0.4 0.086 12.4 0.4 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 GBG67731.1 - 0.093 12.1 0.3 0.15 11.4 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 GBG67732.1 - 8.5e-17 60.7 0.0 1.4e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GBG67732.1 - 2.3e-06 27.4 2.8 4.1e-06 26.6 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-Nse PF11789.8 GBG67733.1 - 1.1e-07 31.5 0.9 2.3e-07 30.5 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Vac_Fusion PF02346.16 GBG67733.1 - 0.074 12.7 2.0 4.8 6.9 0.1 2.8 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 zf-rbx1 PF12678.7 GBG67733.1 - 0.29 11.4 3.2 1.3 9.4 3.2 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain CLTH PF10607.9 GBG67735.1 - 1.2e-40 138.8 1.1 1.7e-40 138.3 1.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain P53_TAD PF08563.11 GBG67735.1 - 0.12 11.9 0.1 0.32 10.5 0.1 1.7 1 0 0 1 1 1 0 P53 transactivation motif Prenylcys_lyase PF07156.14 GBG67736.1 - 1.2e-48 166.1 0.0 1.8e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 GBG67736.1 - 2.1e-12 47.1 0.0 3.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG67736.1 - 4.6e-06 26.8 2.3 0.017 15.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG67736.1 - 0.012 15.2 0.4 1 8.9 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Serglycin PF04360.12 GBG67736.1 - 0.13 12.2 1.1 0.25 11.3 1.1 1.3 1 0 0 1 1 1 0 Serglycin Josephin PF02099.17 GBG67737.1 - 1.3e-51 175.0 0.0 2e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Josephin UBX PF00789.20 GBG67737.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 UBX domain ABC_membrane PF00664.23 GBG67738.1 - 3.3e-37 128.7 11.8 4.2e-37 128.3 11.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GBG67738.1 - 9.3e-30 103.9 0.0 2.1e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter PRK PF00485.18 GBG67738.1 - 0.0021 17.9 0.7 0.055 13.2 0.0 2.6 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.6 GBG67738.1 - 0.0022 17.8 0.1 0.0043 16.8 0.0 1.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 GBG67738.1 - 0.0058 17.0 0.0 0.024 15.0 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG67738.1 - 0.0064 16.8 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 GBG67738.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 GBG67738.1 - 0.017 15.6 0.0 0.041 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GBG67738.1 - 0.019 14.7 0.2 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GBG67738.1 - 0.026 13.8 0.2 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 GBG67738.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 GBG67738.1 - 0.077 12.7 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 GBG67738.1 - 0.082 13.0 0.3 0.22 11.6 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 GBG67738.1 - 0.12 12.7 0.0 0.37 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GBG67738.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NST1 PF13945.6 GBG67741.1 - 5.7 7.0 18.7 9.1 6.3 18.7 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Menin PF05053.13 GBG67741.1 - 8 4.7 12.4 11 4.3 12.4 1.2 1 0 0 1 1 1 0 Menin EOS1 PF12326.8 GBG67741.1 - 8.1 6.3 6.5 13 5.7 6.5 1.5 1 1 0 1 1 1 0 N-glycosylation protein zf-primase PF09329.11 GBG67742.1 - 1.5e-15 56.7 0.6 4.9e-15 55.1 0.6 2.0 1 0 0 1 1 1 1 Primase zinc finger GSHPx PF00255.19 GBG67743.1 - 3.4e-42 142.4 0.2 4.5e-42 142.0 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 GBG67743.1 - 2e-12 47.1 0.3 5.1e-12 45.8 0.3 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GBG67743.1 - 8.3e-09 35.3 0.2 2e-08 34.1 0.2 1.6 1 1 0 1 1 1 1 Redoxin STT3 PF02516.14 GBG67744.1 - 2.3e-126 422.6 42.2 5.7e-121 404.8 38.5 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit RT_RNaseH PF17917.1 GBG67745.1 - 8.3e-19 67.8 0.0 1.5e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67745.1 - 2.1e-16 59.8 0.0 5e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67745.1 - 1.6e-15 57.3 0.0 4.2e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG67745.1 - 2.6e-15 56.3 0.1 6.4e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG67745.1 - 0.0029 17.8 0.0 0.0073 16.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Glycos_transf_N PF04413.16 GBG67746.1 - 6.6e-55 185.5 0.1 2.6e-54 183.6 0.0 1.8 2 0 0 2 2 2 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) SPT6_acidic PF14632.6 GBG67747.1 - 0.0062 17.1 31.8 0.0062 17.1 31.8 5.7 1 1 1 2 2 2 1 Acidic N-terminal SPT6 HTH_44 PF14641.6 GBG67748.1 - 4e-13 49.8 1.4 9.7e-13 48.6 1.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 GBG67748.1 - 8.9e-05 23.0 1.4 8.9e-05 23.0 1.4 5.6 4 2 2 6 6 6 1 Acidic N-terminal SPT6 Tex_N PF09371.10 GBG67748.1 - 0.00059 19.6 0.5 0.84 9.3 0.2 3.1 3 1 0 3 3 3 2 Tex-like protein N-terminal domain Arg_tRNA_synt_N PF03485.16 GBG67748.1 - 0.11 13.0 0.1 1.5 9.4 0.0 2.8 3 0 0 3 3 3 0 Arginyl tRNA synthetase N terminal domain SH2_2 PF14633.6 GBG67749.1 - 6.6e-71 238.1 0.0 1.6e-70 236.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 GBG67749.1 - 1.4e-21 76.8 0.0 2.4e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 GBG67749.1 - 1.8e-14 53.8 0.0 4.7e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HIT PF01230.23 GBG67749.1 - 3.3e-13 50.2 0.2 6.7e-08 33.2 0.0 2.8 2 0 0 2 2 2 2 HIT domain HTH_44 PF14641.6 GBG67749.1 - 4e-12 46.6 1.4 9.6e-12 45.4 1.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.24 GBG67749.1 - 1e-07 32.0 0.0 0.0005 20.1 0.0 2.6 2 0 0 2 2 2 2 SH2 domain DcpS_C PF11969.8 GBG67749.1 - 2.5e-07 31.1 0.2 0.016 15.7 0.0 3.0 3 0 0 3 3 3 2 Scavenger mRNA decapping enzyme C-term binding Tex_N PF09371.10 GBG67749.1 - 3.2e-07 30.2 0.2 5.2e-05 23.0 0.2 2.6 2 0 0 2 2 2 1 Tex-like protein N-terminal domain HHH_9 PF17674.1 GBG67749.1 - 2.2e-05 25.2 0.1 8.2e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 HHH domain HHH_3 PF12836.7 GBG67749.1 - 0.016 15.4 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF601 PF04642.12 GBG67749.1 - 3 7.3 6.7 5.7 6.4 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Pro_isomerase PF00160.21 GBG67750.1 - 6.4e-47 159.8 0.1 7.7e-47 159.5 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3577 PF12101.8 GBG67750.1 - 0.041 13.7 0.0 7 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3577) S10_plectin PF03501.15 GBG67751.1 - 2.5e-46 155.7 0.3 2.9e-46 155.5 0.3 1.0 1 0 0 1 1 1 1 Plectin/S10 domain TFIIE_alpha PF02002.17 GBG67751.1 - 0.18 11.7 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit SH2_2 PF14633.6 GBG67752.1 - 1.7e-73 246.6 0.1 1.7e-73 246.6 0.1 2.4 3 0 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 GBG67752.1 - 7.5e-19 68.0 0.0 1.4e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 GBG67752.1 - 3e-15 56.3 0.0 9.6e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 GBG67752.1 - 3.1e-13 50.2 0.3 1.1e-12 48.4 0.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 GBG67752.1 - 9.1e-08 32.6 42.5 9.1e-08 32.6 42.5 7.4 3 1 1 5 5 5 1 Acidic N-terminal SPT6 Tex_N PF09371.10 GBG67752.1 - 2e-07 30.9 1.0 0.00011 21.9 0.0 3.1 2 1 0 3 3 3 2 Tex-like protein N-terminal domain HHH_9 PF17674.1 GBG67752.1 - 0.0017 19.2 0.3 0.021 15.7 0.3 2.9 1 1 0 1 1 1 1 HHH domain S1 PF00575.23 GBG67752.1 - 0.013 15.8 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 S1 RNA binding domain HHH_3 PF12836.7 GBG67752.1 - 0.13 12.5 0.0 1.1 9.6 0.0 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix motif SH2_2 PF14633.6 GBG67753.1 - 1.7e-73 246.6 0.1 1.7e-73 246.6 0.1 2.4 3 0 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 GBG67753.1 - 7.5e-19 68.0 0.0 1.4e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 GBG67753.1 - 3.1e-15 56.3 0.0 9.6e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 GBG67753.1 - 3.1e-13 50.2 0.3 1.1e-12 48.4 0.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 GBG67753.1 - 1.1e-07 32.4 42.7 1.1e-07 32.4 42.7 7.3 3 1 2 5 5 5 1 Acidic N-terminal SPT6 Tex_N PF09371.10 GBG67753.1 - 2e-07 30.9 1.0 0.00011 21.9 0.0 3.1 2 1 0 3 3 3 2 Tex-like protein N-terminal domain HHH_9 PF17674.1 GBG67753.1 - 0.0017 19.2 0.3 0.021 15.7 0.3 2.9 1 1 0 1 1 1 1 HHH domain S1 PF00575.23 GBG67753.1 - 0.013 15.8 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 S1 RNA binding domain HHH_3 PF12836.7 GBG67753.1 - 0.13 12.5 0.0 1.1 9.6 0.0 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix motif YL1 PF05764.13 GBG67755.1 - 0.013 15.7 1.7 0.032 14.4 1.7 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Dimer_Tnp_hAT PF05699.14 GBG67755.1 - 0.082 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region CDC45 PF02724.14 GBG67755.1 - 0.28 9.5 3.6 0.41 8.9 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG67755.1 - 0.69 8.1 2.1 1 7.5 2.1 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_C1 PF00112.23 GBG67756.1 - 1.4e-77 260.7 0.1 1.9e-77 260.2 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GBG67756.1 - 1.5e-13 51.0 3.5 2.3e-13 50.4 3.5 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Granulin PF00396.18 GBG67756.1 - 3.3e-10 40.1 24.3 3.3e-10 40.1 24.3 2.5 1 1 1 2 2 2 1 Granulin Peptidase_C1_2 PF03051.15 GBG67756.1 - 0.00024 20.0 2.8 0.13 11.0 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family CAP_N PF01213.19 GBG67756.1 - 0.81 9.1 3.4 1.2 8.5 3.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GBG67756.1 - 3.3 7.7 3.7 5.1 7.1 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator H2TH PF06831.14 GBG67758.1 - 1.5e-23 82.6 0.0 2.6e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 GBG67758.1 - 1.1e-16 61.5 0.1 3.5e-16 59.9 0.1 1.9 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.11 GBG67758.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Fapy_DNA_glyco PF01149.24 GBG67759.1 - 4.3e-25 88.6 0.0 1.3e-24 87.1 0.0 1.9 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 GBG67759.1 - 7.6e-24 83.5 0.0 2.6e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 GBG67759.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) RT_RNaseH_2 PF17919.1 GBG67760.1 - 4.8e-29 100.3 0.0 1.8e-14 53.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67760.1 - 5.2e-28 97.4 0.0 1.1e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67760.1 - 3.1e-27 95.6 0.1 5.1e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67760.1 - 7.2e-16 58.0 0.2 1.6e-15 57.0 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG67760.1 - 8.2e-12 44.8 0.0 2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG67760.1 - 7.4e-05 22.9 0.2 0.00017 21.7 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG67764.1 - 1.3e-22 80.1 0.0 2.5e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67764.1 - 1.8e-22 79.3 0.0 4.5e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67764.1 - 1.9e-16 59.9 0.0 4.1e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG67764.1 - 0.00058 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG67764.1 - 0.056 13.7 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG67767.1 - 2.7e-26 92.5 0.0 5e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67767.1 - 3.7e-25 87.9 0.1 2.1e-24 85.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67767.1 - 1e-13 51.4 0.0 1e-13 51.4 0.0 2.7 4 0 0 4 4 4 1 RNase H-like domain found in reverse transcriptase ZapB PF06005.12 GBG67767.1 - 0.012 16.0 0.1 0.012 16.0 0.1 4.0 3 1 0 3 3 3 0 Cell division protein ZapB gag-asp_proteas PF13975.6 GBG67767.1 - 0.021 15.4 0.2 0.087 13.4 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67767.1 - 0.071 13.8 0.0 0.24 12.1 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG67767.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Paf1 PF03985.13 GBG67768.1 - 4 6.3 6.0 5.3 5.9 6.0 1.1 1 0 0 1 1 1 0 Paf1 GDP_Man_Dehyd PF16363.5 GBG67769.1 - 8.1 5.7 12.9 0.071 12.5 2.4 2.1 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase FAM76 PF16046.5 GBG67770.1 - 7.6 5.8 21.6 1.3 8.3 18.0 1.5 2 0 0 2 2 2 0 FAM76 protein Integrase_H2C2 PF17921.1 GBG67771.1 - 2.7e-19 69.0 0.0 5.5e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG67771.1 - 9e-15 54.9 0.0 1.8e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG67771.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG67771.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG67771.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG67772.1 - 2.4e-40 138.4 0.0 4e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG67772.1 - 7.6e-30 104.1 0.0 1.4e-29 103.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG67772.1 - 2.8e-26 92.5 0.0 4.4e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-RVT PF13966.6 GBG67772.1 - 0.00046 20.9 6.4 0.0031 18.2 6.4 2.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase rve PF00665.26 GBG67772.1 - 0.059 13.6 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain BRCT_2 PF16589.5 GBG67774.1 - 2.8e-05 24.4 0.0 6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RNA_pol_Rpc4 PF05132.14 GBG67775.1 - 8.3e-26 91.2 2.3 1e-25 90.9 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase III RPC4 DUF3444 PF11926.8 GBG67776.1 - 6e-48 163.3 0.0 9.1e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3444) DUF5571 PF17732.1 GBG67776.1 - 0.28 10.6 1.4 0.52 9.7 1.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5571) DUF3444 PF11926.8 GBG67778.1 - 2.6e-43 148.1 0.0 1.3e-42 145.9 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3444) DnaJ PF00226.31 GBG67778.1 - 1.6e-19 69.8 0.0 3.7e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.13 GBG67778.1 - 2.5e-05 24.5 57.4 0.00019 21.5 18.4 3.2 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit zinc_ribbon_4 PF13717.6 GBG67778.1 - 0.029 14.3 2.1 0.072 13.0 2.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain BSP_II PF05432.11 GBG67778.1 - 1.6 8.4 34.0 0.96 9.1 7.4 3.2 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) FAD_binding_7 PF03441.14 GBG67780.1 - 5.4e-56 189.3 0.0 1.6e-55 187.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GBG67780.1 - 9e-42 142.9 0.0 2.1e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase VIR_N PF15912.5 GBG67781.1 - 2e-13 50.6 0.1 2e-13 50.6 0.1 9.5 5 2 4 9 9 9 2 Virilizer, N-terminal Myb_DNA-bind_4 PF13837.6 GBG67782.1 - 1.8e-11 44.2 3.8 1.8e-11 44.2 3.8 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG67782.1 - 0.19 11.9 2.1 0.36 11.0 0.6 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain T3SSipB PF16535.5 GBG67783.1 - 0.01 16.4 2.8 0.015 15.8 2.8 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB DHR10 PF18595.1 GBG67783.1 - 0.023 14.7 10.6 1.1 9.3 1.4 3.6 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain KELK PF15796.5 GBG67783.1 - 0.023 15.1 1.4 0.059 13.8 1.4 1.7 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Golgin_A5 PF09787.9 GBG67783.1 - 0.034 13.6 3.2 0.088 12.3 1.1 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 GAS PF13851.6 GBG67783.1 - 0.049 13.0 1.4 0.19 11.1 0.2 2.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CorA PF01544.18 GBG67783.1 - 0.77 9.0 4.1 1.1 8.5 3.6 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein OEP PF02321.18 GBG67783.1 - 3.8 7.3 7.4 0.34 10.7 2.3 1.7 2 0 0 2 2 2 0 Outer membrane efflux protein DUF4140 PF13600.6 GBG67783.1 - 9.7 6.7 9.3 4.7e+02 1.3 7.1 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Presenilin PF01080.17 GBG67784.1 - 0.032 13.0 13.6 0.045 12.5 13.6 1.3 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 GBG67784.1 - 1.6 7.0 4.3 2.2 6.6 4.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Mito_carr PF00153.27 GBG67785.1 - 7e-70 231.0 1.0 1.2e-23 82.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Laminin_G_3 PF13385.6 GBG67786.1 - 1.6e-143 473.2 53.9 9.2e-17 61.6 0.3 17.7 16 1 1 17 17 17 16 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 GBG67786.1 - 5e-38 130.5 2.8 1.5e-05 25.6 0.1 11.6 11 0 0 11 11 11 6 Laminin G domain REJ PF02010.15 GBG67786.1 - 3.4e-33 115.1 0.0 7.9e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 REJ domain Big_9 PF17963.1 GBG67786.1 - 3.7e-22 78.9 38.1 0.00042 21.0 0.1 14.3 14 0 0 14 14 14 5 Bacterial Ig domain Cadherin_3 PF16184.5 GBG67786.1 - 4.5e-19 68.5 12.2 0.068 13.2 0.1 13.2 14 0 0 14 14 14 5 Cadherin-like Laminin_G_1 PF00054.23 GBG67786.1 - 6.5e-18 65.2 0.3 0.024 14.8 0.0 8.9 9 0 0 9 9 9 4 Laminin G domain Cadherin_4 PF17803.1 GBG67786.1 - 2.9e-11 43.8 45.7 0.0065 17.1 2.3 12.9 14 0 0 14 14 14 4 Bacterial cadherin-like domain Cadherin_5 PF17892.1 GBG67786.1 - 2e-10 40.5 3.3 2.9 7.9 0.0 9.3 7 1 0 7 7 7 2 Cadherin-like domain Glyco_hydro_16 PF00722.21 GBG67786.1 - 0.0019 17.7 0.8 6.8 6.1 0.0 4.6 5 0 0 5 5 5 2 Glycosyl hydrolases family 16 PRIMA1 PF16101.5 GBG67786.1 - 0.64 10.1 2.8 13 5.8 0.0 3.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Vac7 PF12751.7 GBG67787.1 - 0.085 12.3 4.3 0.099 12.1 3.1 1.7 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 DUF2345 PF10106.9 GBG67787.1 - 0.18 11.7 1.9 0.34 10.8 1.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Rota_NSP4 PF01452.16 GBG67787.1 - 2.8 7.6 8.6 9.3 5.9 0.0 2.8 3 0 0 3 3 3 0 Rotavirus non structural protein RRM_1 PF00076.22 GBG67788.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.27 GBG67789.1 - 1e-30 107.0 0.2 1.9e-30 106.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67789.1 - 3e-21 75.3 0.1 6.6e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67789.1 - 1.3e-09 38.3 0.0 3.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG67789.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG67790.1 - 9.4e-31 107.0 0.2 1.8e-30 106.1 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67790.1 - 2.9e-21 75.4 0.1 6.4e-21 74.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67790.1 - 1.2e-09 38.4 0.0 3.1e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG67790.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TPR_1 PF00515.28 GBG67793.1 - 5.7e-37 124.0 16.1 4.2e-05 23.2 0.0 8.9 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 GBG67793.1 - 9.7e-34 112.8 19.7 0.0026 17.7 0.0 9.9 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_9 PF13371.6 GBG67793.1 - 5.1e-19 68.2 19.0 1.1e-07 31.9 4.0 6.1 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 GBG67793.1 - 1.8e-16 58.9 10.9 0.004 17.3 0.0 9.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG67793.1 - 6.1e-14 51.4 9.8 7.1e-05 22.4 0.0 7.7 4 3 5 9 9 9 2 TPR repeat RPAP3_C PF13877.6 GBG67793.1 - 2.6e-13 50.3 0.0 1.4e-12 48.0 0.0 2.1 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_19 PF14559.6 GBG67793.1 - 2.3e-12 47.3 17.7 0.0007 20.1 0.1 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 GBG67793.1 - 5.6e-10 38.9 12.9 0.0054 17.0 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG67793.1 - 2.7e-09 37.5 23.4 0.0018 18.9 0.2 6.0 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 GBG67793.1 - 3.2e-06 27.3 21.3 0.013 15.7 0.5 6.0 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG67793.1 - 2.6e-05 23.9 5.3 2.6 8.3 0.2 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GBG67793.1 - 6.7e-05 22.9 1.4 0.69 10.0 0.0 4.2 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 GBG67793.1 - 0.00023 21.6 15.9 0.099 13.1 0.1 3.9 3 1 0 3 3 3 2 Bacterial transcriptional activator domain DUF3856 PF12968.7 GBG67793.1 - 0.00032 20.8 2.6 1.3 9.1 0.0 4.0 3 2 0 3 3 3 2 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 GBG67793.1 - 0.0094 16.7 20.4 1.4 9.9 2.1 7.4 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG67793.1 - 0.014 15.3 17.0 0.53 10.2 0.5 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG67793.1 - 0.02 15.1 5.1 0.87 9.9 2.6 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Desmo_N PF06771.11 GBG67793.1 - 0.095 13.1 0.0 1.6 9.1 0.0 2.9 3 1 0 4 4 3 0 Viral Desmoplakin N-terminus EPL1 PF10513.9 GBG67793.1 - 0.3 11.4 16.5 0.64 10.4 8.7 2.9 2 0 0 2 2 2 0 Enhancer of polycomb-like TPR_6 PF13174.6 GBG67793.1 - 3.1 8.6 16.2 24 5.9 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat Ctr PF04145.15 GBG67793.1 - 5.6 7.6 12.4 12 6.5 0.8 3.0 2 0 0 2 2 2 0 Ctr copper transporter family Eapp_C PF10238.9 GBG67793.1 - 5.7 7.0 16.8 2.8 8.0 6.5 3.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Spem1 PF15670.5 GBG67793.1 - 7.6 6.0 13.4 3.4 7.2 6.1 2.8 2 0 0 2 2 2 0 Spermatid maturation protein 1 Integrase_H2C2 PF17921.1 GBG67795.1 - 3.5e-16 59.1 0.6 9e-16 57.7 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG67795.1 - 5.3e-12 46.0 0.0 1.2e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG67795.1 - 2.1e-05 24.7 0.0 4.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Dppa2_A PF14049.6 GBG67795.1 - 0.055 13.6 1.3 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates Goodbye PF17109.5 GBG67796.1 - 0.035 14.5 1.6 0.82 10.1 0.1 2.9 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain TLP-20 PF06088.11 GBG67796.1 - 0.78 9.6 9.2 1.7 8.5 1.9 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RRM_1 PF00076.22 GBG67797.1 - 7.6e-19 67.3 0.0 1.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 GBG67797.1 - 1.1e-05 25.2 3.5 2.5e-05 24.1 3.5 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_7 PF16367.5 GBG67797.1 - 7.3e-05 22.8 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif Torus PF16131.5 GBG67797.1 - 0.00021 22.0 0.3 0.00021 22.0 0.3 3.2 3 1 1 4 4 4 1 Torus domain zf_CCCH_4 PF18345.1 GBG67797.1 - 0.017 15.2 6.9 0.017 15.2 6.9 1.8 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 GBG67797.1 - 0.32 10.9 4.1 0.79 9.6 4.1 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger PGAP1 PF07819.13 GBG67798.1 - 4.2e-75 252.4 0.0 6.3e-75 251.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GBG67798.1 - 2.9e-05 24.8 0.0 2.9e-05 24.8 0.0 3.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG67798.1 - 0.00064 19.1 0.3 0.0012 18.1 0.3 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 GBG67798.1 - 0.046 13.2 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 GBG67798.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase TMEM125 PF15109.6 GBG67798.1 - 4.8 7.5 6.0 0.81 10.0 0.6 2.4 2 0 0 2 2 2 0 TMEM125 protein family ELO PF01151.18 GBG67800.1 - 2.8e-54 184.3 17.2 3.3e-54 184.1 17.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF5527 PF17665.1 GBG67801.1 - 0.11 12.1 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5527) AIM24 PF01987.17 GBG67802.1 - 1.6e-48 165.2 0.1 1.8e-48 165.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 AIM24 PF01987.17 GBG67803.1 - 2.3e-46 158.1 0.1 2.7e-46 157.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 AIM24 PF01987.17 GBG67804.1 - 2.2e-49 168.0 0.2 2.6e-49 167.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 RVT_1 PF00078.27 GBG67805.1 - 2.2e-32 112.4 0.1 3.5e-32 111.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67805.1 - 3.5e-29 100.8 0.1 1.6e-28 98.7 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67805.1 - 8.2e-16 58.2 0.0 2.3e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG67805.1 - 0.00082 19.3 1.5 0.0017 18.2 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG67806.1 - 3.3e-30 104.1 0.1 1.3e-28 99.0 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67806.1 - 2e-20 73.0 0.1 1.1e-19 70.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67806.1 - 7.3e-09 35.5 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG67806.1 - 0.26 10.9 8.3 2.7 7.5 4.1 2.5 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase YabA PF06156.13 GBG67806.1 - 0.8 10.4 0.0 0.8 10.4 0.0 3.0 3 0 0 3 3 3 0 Initiation control protein YabA Ax_dynein_light PF10211.9 GBG67807.1 - 0.21 11.5 12.8 3.8 7.4 13.3 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain Ax_dynein_light PF10211.9 GBG67808.1 - 0.28 11.1 13.3 5.9 6.8 13.8 2.6 2 1 0 2 2 2 0 Axonemal dynein light chain DUF1043 PF06295.12 GBG67809.1 - 0.017 15.1 0.4 0.028 14.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Cluap1 PF10234.9 GBG67809.1 - 0.028 13.8 2.7 0.041 13.3 2.7 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF16 PF01519.16 GBG67809.1 - 0.067 13.7 1.3 0.19 12.2 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 CortBP2 PF09727.9 GBG67809.1 - 0.11 12.4 4.2 0.2 11.5 4.2 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 Csm1_N PF18504.1 GBG67809.1 - 0.18 12.1 2.3 0.39 11.1 2.3 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain GrpE PF01025.19 GBG67809.1 - 0.21 11.3 2.2 0.39 10.4 2.2 1.4 1 0 0 1 1 1 0 GrpE DivIC PF04977.15 GBG67809.1 - 0.53 10.1 3.0 1.2 8.9 3.0 1.6 1 0 0 1 1 1 0 Septum formation initiator RVT_1 PF00078.27 GBG67810.1 - 3.2e-34 118.4 0.0 4.9e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67810.1 - 7.7e-23 80.4 0.0 2e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67810.1 - 5.5e-11 42.7 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase eIF-4B PF06273.11 GBG67812.1 - 4.5e-84 283.3 69.1 1.6e-54 185.8 34.8 4.8 1 1 1 3 3 3 2 Plant specific eukaryotic initiation factor 4B eIF-4B PF06273.11 GBG67813.1 - 1.4e-84 285.0 66.6 1.2e-54 186.2 35.5 4.7 1 1 2 3 3 3 2 Plant specific eukaryotic initiation factor 4B eIF-4B PF06273.11 GBG67814.1 - 3.5e-87 293.6 57.0 7.7e-55 186.9 33.9 4.1 1 1 1 2 2 2 2 Plant specific eukaryotic initiation factor 4B DUF4346 PF14251.6 GBG67816.1 - 2.4e-47 159.8 0.0 3.4e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4346) DUF543 PF04418.12 GBG67816.1 - 0.33 11.0 1.7 0.76 9.8 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Sec23_trunk PF04811.15 GBG67818.1 - 4.4e-16 59.2 0.0 7.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GBG67818.1 - 1.2e-11 45.1 0.0 2.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 GBG67818.1 - 8.2e-10 38.4 0.0 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GBG67818.1 - 1.8e-08 34.3 3.9 3.3e-08 33.5 3.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GBG67818.1 - 1.5e-05 24.8 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zinc_ribbon_10 PF10058.9 GBG67818.1 - 0.032 13.9 2.7 0.067 12.9 2.7 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-RanBP PF00641.18 GBG67818.1 - 0.65 9.4 3.1 3.5 7.0 0.4 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Toprim_N PF08275.11 GBG67819.1 - 0.01 15.9 0.3 41 4.2 0.0 4.5 2 1 1 3 3 3 0 DNA primase catalytic core, N-terminal domain RTA1 PF04479.13 GBG67819.1 - 0.13 11.8 4.2 85 2.7 0.0 4.8 3 2 2 5 5 5 0 RTA1 like protein PapC_C PF13953.6 GBG67819.1 - 0.37 10.6 17.2 13 5.7 0.1 5.8 2 1 4 6 6 6 0 PapC C-terminal domain RT_RNaseH_2 PF17919.1 GBG67820.1 - 3e-25 88.2 0.0 5.6e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67820.1 - 2.7e-23 82.2 0.0 7.8e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67820.1 - 1.7e-10 41.1 0.0 4.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG67820.1 - 0.0073 16.1 0.0 0.024 14.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG67820.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PapC_C PF13953.6 GBG67821.1 - 0.00086 19.1 37.3 8.6 6.3 0.1 10.2 4 3 8 12 12 12 6 PapC C-terminal domain RTA1 PF04479.13 GBG67821.1 - 0.0028 17.3 16.8 45 3.6 0.0 9.3 4 3 7 11 11 11 1 RTA1 like protein SH3_19 PF18597.1 GBG67821.1 - 4 7.4 62.4 18 5.2 0.1 14.1 15 0 0 15 15 15 0 Myosin X N-terminal SH3 domain DdrB PF12747.7 GBG67821.1 - 9.7 6.0 27.1 11 5.8 0.3 7.3 4 3 3 8 8 8 0 DdrB-like protein Thioredoxin PF00085.20 GBG67822.1 - 1.3e-06 28.4 0.1 2.3e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 GBG67822.1 - 0.002 17.1 0.2 0.0038 16.2 0.1 1.4 1 1 0 1 1 1 1 Phosducin Myco_haema PF05692.12 GBG67824.1 - 0.026 13.5 2.9 0.034 13.1 2.9 1.3 1 0 0 1 1 1 0 Mycoplasma haemagglutinin DNA_pol_phi PF04931.13 GBG67824.1 - 0.063 11.4 29.3 0.061 11.4 29.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop25 PF09805.9 GBG67824.1 - 0.088 13.3 24.5 0.1 13.1 24.5 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) BUD22 PF09073.10 GBG67824.1 - 0.11 11.9 25.7 0.11 11.8 25.7 1.0 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 GBG67824.1 - 0.23 11.4 21.6 0.32 10.9 21.6 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 GBG67824.1 - 0.4 8.8 28.6 0.4 8.8 28.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4366 PF14283.6 GBG67824.1 - 0.6 10.2 17.9 0.79 9.8 17.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Tim54 PF11711.8 GBG67824.1 - 1 8.0 16.6 1.1 7.9 16.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BORG_CEP PF14957.6 GBG67824.1 - 1.1 10.4 9.7 1.3 10.2 9.7 1.2 1 0 0 1 1 1 0 Cdc42 effector CDC27 PF09507.10 GBG67824.1 - 1.2 8.5 25.2 1.2 8.4 25.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RNA_pol_3_Rpc31 PF11705.8 GBG67824.1 - 1.3 9.2 33.0 1.8 8.8 33.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 GBG67824.1 - 1.4 8.2 18.4 1.8 7.8 18.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2072 PF09845.9 GBG67824.1 - 1.6 9.0 15.7 2.1 8.6 15.7 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF4746 PF15928.5 GBG67824.1 - 1.6 8.1 28.8 1.9 7.8 28.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TRAP_alpha PF03896.16 GBG67824.1 - 1.6 7.9 15.8 1.9 7.7 15.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cellulose_synt PF03552.14 GBG67824.1 - 1.9 6.8 6.6 2 6.8 6.6 1.0 1 0 0 1 1 1 0 Cellulose synthase SpoIIP PF07454.11 GBG67824.1 - 2 7.8 17.0 2.3 7.6 17.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Afi1 PF07792.12 GBG67824.1 - 2.2 8.8 13.6 2.7 8.5 13.6 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NPR3 PF03666.13 GBG67824.1 - 2.3 6.9 13.2 2.5 6.8 13.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 GBG67824.1 - 2.4 6.4 24.5 2.5 6.3 24.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG67824.1 - 2.4 6.8 16.4 2.4 6.8 16.4 1.0 1 0 0 1 1 1 0 Presenilin Nop53 PF07767.11 GBG67824.1 - 2.6 7.3 32.9 2.9 7.2 32.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DDHD PF02862.17 GBG67824.1 - 2.7 8.1 8.0 3.3 7.8 8.0 1.2 1 0 0 1 1 1 0 DDHD domain CobT PF06213.12 GBG67824.1 - 2.7 7.3 27.2 3.3 7.0 27.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4471 PF14740.6 GBG67824.1 - 3 7.0 11.1 3.5 6.8 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) CSRNP_N PF16019.5 GBG67824.1 - 3 7.7 12.9 3.2 7.6 12.9 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF2151 PF10221.9 GBG67824.1 - 3.1 6.3 16.1 3.2 6.2 16.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4045 PF13254.6 GBG67824.1 - 3.3 7.2 15.7 3.6 7.1 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.6 GBG67824.1 - 3.5 7.6 12.4 4.2 7.3 12.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Vfa1 PF08432.10 GBG67824.1 - 3.9 7.8 23.6 4.8 7.5 23.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.14 GBG67824.1 - 4 7.9 12.7 5.8 7.3 12.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 GBG67824.1 - 4.3 7.1 26.7 5.1 6.8 26.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Membralin PF09746.9 GBG67824.1 - 4.4 6.3 10.1 5 6.1 10.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF913 PF06025.12 GBG67824.1 - 4.6 6.1 12.9 4.8 6.1 12.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FUSC PF04632.12 GBG67824.1 - 5.4 5.4 8.0 6.5 5.2 8.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PI3K_1B_p101 PF10486.9 GBG67824.1 - 5.7 4.6 11.2 7.1 4.3 11.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SAPS PF04499.15 GBG67824.1 - 5.8 5.6 14.1 6 5.5 14.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Merozoite_SPAM PF07133.11 GBG67824.1 - 6.2 6.8 42.9 7.8 6.5 42.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Raftlin PF15250.6 GBG67824.1 - 6.8 5.3 13.8 7.5 5.2 13.8 1.0 1 0 0 1 1 1 0 Raftlin DUF3499 PF12005.8 GBG67824.1 - 7.2 7.2 8.2 9 6.9 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) FGF-BP1 PF06473.12 GBG67824.1 - 7.7 6.3 16.6 8.8 6.1 16.6 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Spore_coat_CotO PF14153.6 GBG67824.1 - 8.5 6.3 25.2 10 6.0 25.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO LAP1C PF05609.12 GBG67824.1 - 8.7 5.3 15.3 9.3 5.2 15.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PPL5 PF18168.1 GBG67824.1 - 9.1 5.5 14.3 11 5.3 14.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Drc1-Sld2 PF11719.8 GBG67824.1 - 9.7 5.6 22.2 11 5.5 22.2 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein ULD PF16534.5 GBG67825.1 - 0.0039 17.2 0.4 0.0081 16.2 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-like oligomerisation domain of SATB DUF659 PF04937.15 GBG67826.1 - 2.1e-29 102.3 0.0 3.3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) WD40 PF00400.32 GBG67826.1 - 2.1e-06 28.3 6.9 0.53 11.2 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat NYD-SP28 PF14772.6 GBG67826.1 - 3 7.9 7.8 0.56 10.3 4.0 1.8 2 0 0 2 2 2 0 Sperm tail RVT_1 PF00078.27 GBG67827.1 - 8.1e-34 117.1 0.1 1.7e-33 116.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67827.1 - 1.3e-29 102.2 0.0 2.9e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67827.1 - 4.3e-26 91.2 0.0 9.7e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67827.1 - 5.8e-13 48.7 0.1 1.3e-12 47.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG67827.1 - 0.002 18.3 0.0 0.0077 16.4 0.0 2.0 2 0 0 2 2 2 1 H2C2 zinc finger tRNA-synt_1 PF00133.22 GBG67828.1 - 4.7e-41 140.7 0.0 1.1e-32 113.1 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GBG67828.1 - 1.4e-16 60.2 0.7 7.4e-10 38.1 0.0 3.2 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GBG67828.1 - 1.8e-11 44.3 0.0 3.4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 GBG67828.1 - 2.9e-11 43.3 0.0 5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 GBG67828.1 - 0.068 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) CBM53 PF16760.5 GBG67829.1 - 8e-55 183.4 11.1 4.9e-18 65.5 1.1 3.6 3 0 0 3 3 3 3 Starch/carbohydrate-binding module (family 53) Glyco_transf_5 PF08323.11 GBG67829.1 - 1.5e-50 172.1 0.2 5.1e-48 163.9 0.2 2.4 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 GBG67829.1 - 4.5e-12 46.3 0.1 2e-11 44.2 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 GBG67829.1 - 1.6e-08 34.2 0.0 1.6e-07 31.0 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GBG67829.1 - 1.8e-08 35.0 0.0 7.2e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain AMPK1_CBM PF16561.5 GBG67829.1 - 0.027 14.7 1.2 2.3 8.5 0.4 2.9 3 0 0 3 3 3 0 Glycogen recognition site of AMP-activated protein kinase DUF3592 PF12158.8 GBG67829.1 - 0.03 14.4 0.0 0.094 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) FAINT PF04385.15 GBG67829.1 - 0.4 10.8 1.1 8.5 6.5 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function, DUF529 DUF3458_C PF17432.2 GBG67830.1 - 5e-121 404.0 4.4 7.4e-121 403.4 4.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 GBG67830.1 - 5.5e-51 173.2 0.0 1e-50 172.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 GBG67830.1 - 2.8e-28 98.2 0.0 1e-27 96.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 GBG67830.1 - 3.1e-16 60.1 0.0 8.1e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 GBG67830.1 - 0.0031 17.9 0.4 0.071 13.5 0.2 2.8 2 1 0 2 2 2 1 M61 glycyl aminopeptidase SMG1 PF15785.5 GBG67831.1 - 0.35 9.2 0.9 1.8 6.9 0.1 2.0 2 0 0 2 2 2 0 Serine/threonine-protein kinase smg-1 NAM-associated PF14303.6 GBG67831.1 - 6.7 7.4 7.7 2.5e+02 2.3 0.0 3.5 3 1 0 3 3 3 0 No apical meristem-associated C-terminal domain Dicty_REP PF05086.12 GBG67831.1 - 6.9 4.5 6.5 11 3.8 6.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF676 PF05057.14 GBG67832.1 - 1e-45 155.9 0.0 1.5e-26 93.3 0.0 3.0 3 0 0 3 3 3 2 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 GBG67832.1 - 0.057 14.0 1.2 0.14 12.7 0.2 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Secretin_N_2 PF07655.13 GBG67832.1 - 0.17 12.4 24.4 0.98 10.0 0.1 3.8 3 0 0 3 3 3 0 Secretin N-terminal domain zf-CCCH_4 PF18044.1 GBG67833.1 - 1.3e-06 28.0 1.7 1.3e-06 28.0 1.7 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 GBG67833.1 - 0.0029 17.5 1.8 0.0029 17.5 1.8 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 GBG67833.1 - 0.017 15.3 0.2 0.046 13.9 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger containing family zf_CCCH_4 PF18345.1 GBG67833.1 - 0.019 15.0 5.1 0.019 15.0 5.1 2.5 2 1 0 2 2 2 0 Zinc finger domain zf-C2H2_4 PF13894.6 GBG67833.1 - 0.087 13.7 0.3 0.21 12.5 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 GBG67833.1 - 0.27 11.0 0.5 0.49 10.2 0.5 1.3 1 0 0 1 1 1 0 zinc-finger C2H2-type RRM_1 PF00076.22 GBG67834.1 - 5.5e-16 58.2 0.0 1e-15 57.3 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-binding PF00249.31 GBG67835.1 - 3.7e-05 23.8 0.0 6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DnaJ_C PF01556.18 GBG67836.1 - 4.3e-32 111.3 0.3 5.6e-32 110.9 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GBG67836.1 - 1e-21 76.8 0.3 2.4e-21 75.6 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain Pkinase_Tyr PF07714.17 GBG67838.1 - 1.2e-30 106.7 0.0 2.5e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG67838.1 - 2.4e-27 96.0 0.0 7.3e-27 94.4 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Tropomyosin_1 PF12718.7 GBG67838.1 - 0.0055 16.9 12.4 0.0055 16.9 12.4 20.6 8 5 13 21 21 21 5 Tropomyosin like Pex2_Pex12 PF04757.14 GBG67839.1 - 3.9e-29 101.8 0.4 3.9e-29 101.8 0.4 1.8 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 GBG67839.1 - 4.7e-07 29.6 5.5 4.7e-07 29.6 5.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG67839.1 - 2e-06 27.5 4.0 2e-06 27.5 4.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG67839.1 - 0.00017 21.5 7.5 0.00017 21.5 7.5 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG67839.1 - 0.00019 21.3 6.3 0.00019 21.3 6.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GBG67839.1 - 0.002 17.9 7.0 0.002 17.9 7.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG67839.1 - 0.0045 17.3 6.7 0.0045 17.3 6.7 2.3 3 0 0 3 3 2 1 Ring finger domain Prok-RING_4 PF14447.6 GBG67839.1 - 0.0049 16.7 5.2 0.0049 16.7 5.2 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 GBG67839.1 - 0.1 12.9 6.0 1.8 8.9 0.8 3.0 3 0 0 3 3 2 0 zinc-ribbon CpXC PF14353.6 GBG67839.1 - 0.14 12.2 0.2 0.75 9.9 0.0 2.1 2 0 0 2 2 2 0 CpXC protein zf-C2H2_4 PF13894.6 GBG67839.1 - 0.36 11.8 0.0 0.36 11.8 0.0 3.4 3 0 0 3 3 2 0 C2H2-type zinc finger zf-MIZ PF02891.20 GBG67839.1 - 0.55 10.0 4.8 1.6 8.5 4.8 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Zn_Tnp_IS1595 PF12760.7 GBG67839.1 - 0.57 10.2 2.8 29 4.8 0.2 3.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C3HC4_4 PF15227.6 GBG67839.1 - 0.82 9.9 10.7 0.4 10.9 7.3 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GBG67839.1 - 1 9.7 4.4 2.6 8.4 2.8 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain DZR PF12773.7 GBG67839.1 - 6.2 6.9 7.0 27 4.9 3.6 2.6 2 0 0 2 2 2 0 Double zinc ribbon CPBP PF02517.16 GBG67840.1 - 2.5e-16 59.8 4.3 2.5e-16 59.8 4.3 2.1 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease zf-RVT PF13966.6 GBG67841.1 - 3.3e-07 30.9 5.4 3.3e-07 30.9 5.4 2.7 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 GBG67841.1 - 0.038 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Toprim_Crpt PF13342.6 GBG67841.1 - 0.16 11.9 0.3 28 4.8 0.0 2.6 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase FA_desaturase PF00487.24 GBG67842.1 - 8.4e-33 114.3 17.6 8.4e-33 114.3 17.6 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 GBG67842.1 - 1.7e-21 76.1 0.0 3.2e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NDUFV3 PF15880.5 GBG67842.1 - 0.022 14.8 0.3 0.96 9.5 0.0 2.5 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial zf-CCHC PF00098.23 GBG67843.1 - 0.017 15.2 1.4 0.036 14.1 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG67843.1 - 2.5 8.0 6.1 0.25 11.2 1.4 1.7 2 0 0 2 2 2 0 Zinc knuckle DNA_pol_A_exo1 PF01612.20 GBG67844.1 - 1.4e-15 57.4 0.0 2.3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.6 GBG67844.1 - 3.3e-10 40.3 0.1 1e-09 38.7 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 GBG67844.1 - 2.2e-05 24.0 0.3 0.00012 21.7 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 GerE PF00196.19 GBG67844.1 - 0.014 14.9 0.1 0.034 13.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family SPT6_acidic PF14632.6 GBG67845.1 - 0.0012 19.4 8.9 0.0012 19.4 8.9 6.4 2 1 1 3 3 3 1 Acidic N-terminal SPT6 Coilin_N PF15862.5 GBG67845.1 - 0.0014 18.5 4.7 0.0014 18.5 4.7 4.4 2 1 1 3 3 3 2 Coilin N-terminus RT_RNaseH_2 PF17919.1 GBG67846.1 - 9.5e-30 102.6 0.0 2.2e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67846.1 - 1.4e-28 100.0 0.8 7.8e-22 77.9 0.2 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67846.1 - 1.3e-25 89.7 0.0 2.8e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rhamno_transf PF11316.8 GBG67846.1 - 0.019 14.4 3.7 0.083 12.3 0.0 2.8 3 0 0 3 3 3 0 Putative rhamnosyl transferase ThiD2 PF17792.1 GBG67846.1 - 0.066 13.7 1.4 2.6 8.5 0.0 3.2 2 1 1 3 3 3 0 ThiD2 family PAP1 PF08601.10 GBG67846.1 - 0.52 10.0 5.9 0.78 9.4 5.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 COMP PF11598.8 GBG67846.1 - 7.2 7.2 6.7 1 9.9 0.6 2.6 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein ANAPC4_WD40 PF12894.7 GBG67847.1 - 6.3e-06 26.4 0.0 0.005 17.1 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GBG67847.1 - 6.6e-06 26.8 3.9 0.33 11.9 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.11 GBG67847.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A PPL5 PF18168.1 GBG67848.1 - 2.2 7.5 19.5 0.011 15.0 5.5 2.2 2 0 0 2 2 2 0 Prim-pol family 5 RdRP PF05183.12 GBG67850.1 - 4e-181 603.7 0.0 6e-181 603.0 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase RT_RNaseH PF17917.1 GBG67850.1 - 8.6e-23 80.6 0.0 1.7e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67850.1 - 1e-22 80.0 0.0 2e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67850.1 - 9.8e-18 64.0 0.4 2.3e-17 62.8 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG67850.1 - 0.0079 16.5 0.0 0.034 14.4 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein RRM_1 PF00076.22 GBG67850.1 - 0.19 11.6 0.0 0.77 9.6 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_LYR PF05347.15 GBG67851.1 - 9.4e-11 41.6 0.1 1.1e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GBG67851.1 - 0.0022 18.7 0.1 0.0022 18.7 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PMC2NT PF08066.12 GBG67851.1 - 0.071 13.8 0.0 0.082 13.6 0.0 1.1 1 0 0 1 1 1 0 PMC2NT (NUC016) domain RT_RNaseH_2 PF17919.1 GBG67854.1 - 3.6e-26 91.1 0.0 6.6e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67854.1 - 1.2e-23 83.4 0.0 2.5e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HTH_32 PF13565.6 GBG67854.1 - 0.00022 21.8 0.0 0.44 11.2 0.0 3.1 3 0 0 3 3 3 2 Homeodomain-like domain TCTP PF00838.17 GBG67855.1 - 2.1e-56 190.8 0.0 2.3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Big_3 PF07523.12 GBG67855.1 - 0.0079 16.5 1.1 0.052 13.9 0.1 2.5 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 3) rve PF00665.26 GBG67856.1 - 1.3e-15 57.6 0.0 3.6e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG67856.1 - 3.7e-15 55.8 0.1 8.7e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67856.1 - 1.4e-08 34.5 0.0 2.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG67856.1 - 0.0032 17.7 0.0 0.0095 16.1 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG67856.1 - 0.0072 16.9 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67856.1 - 0.14 12.8 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG67857.1 - 2.2e-15 56.5 0.1 5.5e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG67857.1 - 8.1e-09 35.3 0.0 1.6e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67857.1 - 1.8e-06 28.1 0.0 5.5e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG67857.1 - 0.0016 18.6 0.0 0.0061 16.8 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG67857.1 - 0.0045 17.5 0.0 0.0089 16.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67857.1 - 0.094 13.4 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease PTPRCAP PF15713.5 GBG67857.1 - 8.2 6.7 12.7 0.25 11.6 5.5 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Rsm22 PF09243.10 GBG67858.1 - 3.9e-44 151.0 3.1 5.9e-36 124.2 0.0 3.5 2 2 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 GBG67858.1 - 2.8e-06 27.3 0.0 5.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DNA_ligase_OB PF03120.16 GBG67858.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain Cadherin_tail PF15974.5 GBG67859.1 - 0.15 12.4 0.7 0.16 12.3 0.7 1.1 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region NPV_P10 PF05531.12 GBG67860.1 - 0.042 14.3 1.6 0.59 10.6 1.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein RT_RNaseH_2 PF17919.1 GBG67861.1 - 3.9e-25 87.8 0.0 1.2e-24 86.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67861.1 - 1.2e-22 80.5 0.6 1.8e-22 79.9 0.6 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67861.1 - 4.8e-22 78.2 0.0 1.5e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG67861.1 - 3.3e-05 24.5 0.0 0.00011 22.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67861.1 - 7.8e-05 23.2 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67861.1 - 0.0001 22.1 0.0 0.00032 20.5 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67861.1 - 0.0082 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CTU2 PF10288.9 GBG67862.1 - 1.7e-05 25.0 0.0 1.7e-05 25.0 0.0 3.1 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 Rhabdo_ncap PF00945.18 GBG67862.1 - 1.3 7.9 2.5 2.2 7.1 2.5 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Cwf_Cwc_15 PF04889.12 GBG67862.1 - 2.5 7.8 12.3 4.9 6.8 12.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Gram_pos_anchor PF00746.21 GBG67863.1 - 0.057 13.4 0.5 0.21 11.6 0.5 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF1192 PF06698.11 GBG67863.1 - 1.2 9.3 4.4 0.24 11.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1860 PF08949.10 GBG67863.1 - 7.5 6.2 6.8 5.4 6.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) Bystin PF05291.11 GBG67864.1 - 9.1e-158 524.1 13.8 2.1e-125 417.9 7.9 2.9 2 1 0 2 2 2 2 Bystin NOA36 PF06524.12 GBG67864.1 - 0.68 9.2 6.5 1 8.6 6.5 1.2 1 0 0 1 1 1 0 NOA36 protein PMSI1 PF15322.6 GBG67864.1 - 1.2 8.5 3.7 1.9 7.8 3.7 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Bystin PF05291.11 GBG67865.1 - 7e-99 330.8 4.0 8e-99 330.6 4.0 1.0 1 0 0 1 1 1 1 Bystin FSH1 PF03959.13 GBG67866.1 - 2.4e-39 135.2 0.2 1.1e-24 87.4 0.0 2.6 3 0 0 3 3 3 2 Serine hydrolase (FSH1) Rhodanese_C PF12368.8 GBG67866.1 - 5e-15 55.6 7.6 5e-15 55.6 7.6 2.5 2 0 0 2 2 2 1 Rhodanase C-terminal UPF0176_N PF17773.1 GBG67866.1 - 4.3e-10 39.8 0.0 1.5e-09 38.1 0.0 1.8 1 1 1 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 GBG67866.1 - 0.0062 17.0 0.0 0.017 15.7 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_24 PF13578.6 GBG67866.1 - 0.082 13.9 0.1 0.68 11.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Myb_DNA-bind_4 PF13837.6 GBG67867.1 - 1.6e-05 25.2 2.4 1.7e-05 25.1 1.2 1.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG67867.1 - 0.016 15.3 0.8 0.016 15.3 0.8 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Nop14 PF04147.12 GBG67867.1 - 0.19 9.9 23.7 0.28 9.3 23.7 1.2 1 0 0 1 1 1 0 Nop14-like family DDE_Tnp_4 PF13359.6 GBG67868.1 - 4.9e-17 62.0 0.0 9e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67868.1 - 6.2e-09 35.7 0.0 9.2e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67868.1 - 0.63 9.7 4.7 2.8 7.5 1.3 2.6 3 1 0 3 3 3 0 Transposase DDE domain Glycos_transf_1 PF00534.20 GBG67869.1 - 2.4e-29 102.0 0.0 1.2e-22 80.2 0.0 2.4 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG67869.1 - 4.2e-14 53.1 0.0 4.6e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG67869.1 - 9.4e-06 25.7 0.1 1.9e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 GBG67869.1 - 0.022 15.2 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GBG67869.1 - 0.05 14.1 0.2 0.13 12.7 0.1 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain MSA-2c PF12238.8 GBG67869.1 - 9.6 6.1 5.2 15 5.5 5.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Na_trans_assoc PF06512.13 GBG67870.1 - 1.5 9.1 17.3 2 8.6 17.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated DDHD PF02862.17 GBG67870.1 - 1.9 8.6 4.5 2.7 8.1 4.5 1.2 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.12 GBG67870.1 - 2.3 6.4 31.9 3.2 5.8 31.9 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG67870.1 - 5.7 6.2 33.9 7.4 5.8 33.9 1.1 1 0 0 1 1 1 0 BUD22 CPSF100_C PF13299.6 GBG67870.1 - 7.6 6.7 13.7 18 5.5 13.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SAPS PF04499.15 GBG67870.1 - 8.6 5.0 11.2 11 4.6 11.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Syntaxin_2 PF14523.6 GBG67871.1 - 1.8e-28 98.9 9.9 2.4e-28 98.4 1.2 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 GBG67871.1 - 4.1e-14 52.3 2.8 1.1e-13 51.0 2.8 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 GBG67871.1 - 4.2e-07 29.8 12.6 4.2e-07 29.8 12.6 2.7 2 1 0 2 2 2 1 Syntaxin Prominin PF05478.11 GBG67871.1 - 0.00029 19.0 2.0 0.00029 19.0 2.0 2.0 2 0 0 2 2 2 1 Prominin Synaptobrevin PF00957.21 GBG67871.1 - 0.00043 20.0 2.7 0.00087 19.0 2.7 1.5 1 0 0 1 1 1 1 Synaptobrevin Laminin_II PF06009.12 GBG67871.1 - 0.0024 17.9 6.5 0.045 13.8 0.7 2.5 2 1 0 2 2 2 2 Laminin Domain II Orf78 PF06024.12 GBG67871.1 - 0.028 14.7 0.6 0.078 13.3 0.6 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF812 PF05667.11 GBG67871.1 - 0.049 12.5 11.2 0.072 12.0 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Mobilization_B PF17511.2 GBG67871.1 - 0.056 13.8 6.6 1.2 9.5 0.5 2.5 2 0 0 2 2 2 0 Mobilization protein B BAR_3 PF16746.5 GBG67871.1 - 0.079 12.7 4.4 0.1 12.3 0.4 2.2 2 1 0 2 2 2 0 BAR domain of APPL family MCPsignal PF00015.21 GBG67871.1 - 0.16 11.8 9.0 0.038 13.8 1.6 2.9 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4988 PF16378.5 GBG67871.1 - 0.26 11.0 2.4 0.28 10.8 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF5383 PF17355.2 GBG67871.1 - 0.28 11.6 2.4 1.2 9.6 2.4 2.2 1 1 0 1 1 1 0 Family of unknown function (DUF5383) Spc7 PF08317.11 GBG67871.1 - 0.31 9.9 13.5 0.097 11.5 5.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 GBG67871.1 - 0.31 11.2 13.4 2 8.6 13.4 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Rotamase PF00639.21 GBG67871.1 - 0.96 10.5 7.1 0.37 11.8 1.3 2.8 1 1 2 3 3 3 0 PPIC-type PPIASE domain SKA1 PF07160.12 GBG67871.1 - 1.8 8.4 9.5 0.46 10.3 1.6 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF2730 PF10805.8 GBG67871.1 - 1.9 8.6 5.4 45 4.2 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Spectrin PF00435.21 GBG67871.1 - 4.3 7.9 12.1 1.6 9.2 3.0 3.0 2 2 0 3 3 3 0 Spectrin repeat Fib_alpha PF08702.10 GBG67871.1 - 4.5 7.4 8.2 45 4.2 0.0 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Myb_DNA-bind_4 PF13837.6 GBG67872.1 - 0.00044 20.6 1.0 0.00073 19.9 1.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG67874.1 - 1e-25 90.2 0.0 1.6e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67874.1 - 4.9e-15 55.7 0.0 8.5e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67874.1 - 0.00044 19.9 0.7 0.00044 19.9 0.7 2.4 2 1 0 2 2 2 1 Transposase DDE domain DUF4116 PF13475.6 GBG67874.1 - 0.17 11.7 0.0 0.56 10.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) GDP_Man_Dehyd PF16363.5 GBG67875.1 - 5.2e-74 249.6 0.0 2.4e-67 227.7 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG67875.1 - 4e-67 226.2 0.1 1.7e-53 181.6 0.1 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GBG67875.1 - 1.8e-27 96.2 0.0 3.5e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 GBG67875.1 - 3.1e-27 95.3 0.0 2.6e-24 85.7 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GBG67875.1 - 4.5e-24 85.1 0.0 1.3e-17 63.9 0.0 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GBG67875.1 - 2.7e-21 75.9 0.0 1.5e-15 57.1 0.0 3.2 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 GBG67875.1 - 0.05 13.1 0.2 41 3.5 0.0 3.7 4 0 0 4 4 4 0 short chain dehydrogenase Presenilin PF01080.17 GBG67876.1 - 9.6e-06 24.6 0.8 1e-05 24.5 0.8 1.0 1 0 0 1 1 1 1 Presenilin Mpp10 PF04006.12 GBG67876.1 - 0.00022 19.8 20.6 0.00026 19.6 20.6 1.0 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 GBG67876.1 - 0.00087 18.8 24.8 0.001 18.6 24.8 1.1 1 0 0 1 1 1 1 SDA1 Adaptin_binding PF10199.9 GBG67876.1 - 0.0012 19.5 10.2 0.0016 19.0 10.2 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 BUD22 PF09073.10 GBG67876.1 - 0.0017 17.8 17.9 0.0019 17.6 17.9 1.1 1 0 0 1 1 1 1 BUD22 PTPRCAP PF15713.5 GBG67876.1 - 0.0036 17.6 23.9 0.0051 17.1 23.9 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated SpoIIP PF07454.11 GBG67876.1 - 0.0046 16.4 6.9 0.0056 16.2 6.9 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 GBG67876.1 - 0.0053 15.6 7.7 0.0059 15.4 7.7 1.0 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.7 GBG67876.1 - 0.01 15.6 6.0 0.011 15.5 6.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DDHD PF02862.17 GBG67876.1 - 0.011 15.9 0.1 0.011 15.9 0.1 1.1 1 0 0 1 1 1 0 DDHD domain DUF4471 PF14740.6 GBG67876.1 - 0.019 14.2 1.4 0.023 13.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF719 PF05334.13 GBG67876.1 - 0.041 14.1 7.1 0.071 13.3 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF3391 PF11871.8 GBG67876.1 - 0.045 14.3 6.4 0.061 13.9 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Zip PF02535.22 GBG67876.1 - 0.071 12.3 5.2 0.088 12.0 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3402 PF11882.8 GBG67876.1 - 0.086 11.9 9.8 0.098 11.7 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) RIBIOP_C PF04950.12 GBG67876.1 - 0.12 11.7 2.1 0.14 11.5 2.1 1.1 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal FYDLN_acid PF09538.10 GBG67876.1 - 0.17 12.6 18.2 0.28 11.9 18.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Med17 PF10156.9 GBG67876.1 - 0.36 9.5 9.0 0.49 9.0 9.0 1.3 1 0 0 1 1 1 0 Subunit 17 of Mediator complex IDO PF01231.18 GBG67876.1 - 0.47 9.2 4.9 0.64 8.7 4.9 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF4366 PF14283.6 GBG67876.1 - 0.5 10.4 8.4 0.73 9.9 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Plasmodium_Vir PF05795.11 GBG67876.1 - 0.51 9.7 6.8 0.58 9.5 6.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_S64 PF08192.11 GBG67876.1 - 0.77 8.2 2.5 0.83 8.1 2.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF5427 PF10310.9 GBG67876.1 - 0.77 8.7 15.5 1 8.3 15.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF2151 PF10221.9 GBG67876.1 - 0.95 8.0 8.2 1 7.9 8.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator MDM10 PF12519.8 GBG67876.1 - 1.1 8.0 3.5 1.3 7.8 3.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Nop14 PF04147.12 GBG67876.1 - 1.2 7.2 33.7 1.5 6.9 33.7 1.0 1 0 0 1 1 1 0 Nop14-like family EIIBC-GUT_N PF03612.14 GBG67876.1 - 1.4 8.6 6.6 2.1 8.0 6.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Fmp27 PF10344.9 GBG67876.1 - 1.6 6.8 7.4 1.8 6.6 7.4 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 AIF_C PF14721.6 GBG67876.1 - 2 8.8 8.1 3.3 8.1 8.1 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DNA_pol_phi PF04931.13 GBG67876.1 - 2.1 6.3 38.4 2.7 6.0 38.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 GBG67876.1 - 2.8 7.7 23.8 5.6 6.7 23.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BORG_CEP PF14957.6 GBG67876.1 - 3 9.0 5.6 4.4 8.5 5.6 1.2 1 0 0 1 1 1 0 Cdc42 effector Caldesmon PF02029.15 GBG67876.1 - 3.6 6.2 35.9 4.8 5.8 35.9 1.1 1 0 0 1 1 1 0 Caldesmon Raftlin PF15250.6 GBG67876.1 - 3.8 6.1 9.4 4.4 5.9 9.4 1.1 1 0 0 1 1 1 0 Raftlin SAPS PF04499.15 GBG67876.1 - 3.9 6.2 10.9 4.7 5.9 10.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.10 GBG67876.1 - 4.2 7.7 19.2 5.6 7.3 19.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 GBG67876.1 - 4.5 5.4 28.6 5.9 5.0 28.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 GBG67876.1 - 5 7.5 13.0 7.4 7.0 13.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 GBG67876.1 - 5.3 5.9 12.5 7.1 5.5 12.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 GBG67876.1 - 5.5 6.7 13.8 7.8 6.2 13.8 1.2 1 0 0 1 1 1 0 Connexin CobT PF06213.12 GBG67876.1 - 5.6 6.3 33.4 13 5.1 33.3 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4628 PF15429.6 GBG67876.1 - 6.8 6.3 9.6 9 5.9 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) RPN2_C PF18004.1 GBG67876.1 - 8.7 6.2 26.3 15 5.4 26.3 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2457 PF10446.9 GBG67876.1 - 9.7 5.2 35.5 13 4.8 35.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GDP_Man_Dehyd PF16363.5 GBG67877.1 - 2.9e-74 250.4 0.0 1.7e-67 228.2 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG67877.1 - 2.3e-67 226.9 0.1 1.2e-53 182.0 0.1 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GBG67877.1 - 9.8e-28 97.1 0.0 2.6e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 GBG67877.1 - 2.1e-27 95.9 0.0 1.9e-24 86.1 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GBG67877.1 - 2.4e-24 86.0 0.0 9.8e-18 64.3 0.0 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GBG67877.1 - 1.6e-21 76.7 0.0 1.3e-15 57.3 0.0 3.1 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 GBG67877.1 - 0.027 13.9 0.2 35 3.8 0.0 3.8 4 0 0 4 4 4 0 short chain dehydrogenase RVT_1 PF00078.27 GBG67878.1 - 1.6e-15 57.2 0.0 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG67878.1 - 4.2e-07 29.7 0.0 6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG67878.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DEAD PF00270.29 GBG67879.1 - 3e-11 43.4 0.0 7e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GBG67879.1 - 0.1 12.6 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF659 PF04937.15 GBG67880.1 - 4.5e-36 124.0 0.5 7.4e-36 123.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DNA_pol_A PF00476.20 GBG67881.1 - 1.4e-104 350.2 0.0 3.5e-104 348.8 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family A RT_RNaseH_2 PF17919.1 GBG67881.1 - 2.3e-30 104.5 0.0 5.7e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67881.1 - 9.4e-30 103.0 0.0 2.5e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67881.1 - 6.8e-12 45.3 0.1 1.9e-11 43.9 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Helicase_C PF00271.31 GBG67881.1 - 7e-12 45.7 0.0 4.2e-10 40.0 0.0 2.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 GBG67881.1 - 0.00054 20.5 0.3 0.003 18.1 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain Yip1 PF04893.17 GBG67882.1 - 2.7e-14 53.2 8.7 4.2e-14 52.6 8.6 1.4 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 GBG67882.1 - 8e-05 22.3 5.8 0.00068 19.2 5.8 2.0 1 1 0 1 1 1 1 YIF1 DUF3784 PF12650.7 GBG67882.1 - 1.2 9.4 9.0 0.14 12.4 3.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) DUF4820 PF16091.5 GBG67883.1 - 0.018 14.4 2.3 0.024 14.0 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CBF PF03914.17 GBG67883.1 - 0.07 13.2 0.7 0.098 12.7 0.7 1.2 1 0 0 1 1 1 0 CBF/Mak21 family TFB6 PF17110.5 GBG67883.1 - 0.14 11.9 2.1 0.44 10.3 2.1 1.7 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SprA-related PF12118.8 GBG67883.1 - 0.17 11.0 6.1 0.18 10.9 6.1 1.1 1 0 0 1 1 1 0 SprA-related family TMEM208_SND2 PF05620.11 GBG67883.1 - 0.23 11.3 0.6 0.32 10.8 0.6 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Spt20 PF12090.8 GBG67883.1 - 0.7 9.5 11.9 0.9 9.1 11.9 1.2 1 0 0 1 1 1 0 Spt20 family DUF3464 PF11947.8 GBG67883.1 - 2.6 7.8 4.5 3.8 7.2 4.5 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RT_RNaseH_2 PF17919.1 GBG67884.1 - 3.8e-29 100.7 0.0 9.4e-29 99.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67884.1 - 7.6e-28 96.9 0.0 1.4e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67884.1 - 1.1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Btz PF09405.10 GBG67884.1 - 1 9.6 4.6 1.9 8.7 4.6 1.4 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Snf7 PF03357.21 GBG67885.1 - 1e-30 106.6 15.8 1.5e-30 106.0 15.8 1.1 1 0 0 1 1 1 1 Snf7 Mnd1 PF03962.15 GBG67885.1 - 0.049 13.9 1.1 0.16 12.3 1.1 1.8 1 0 0 1 1 1 0 Mnd1 HTH domain LPD14 PF18827.1 GBG67885.1 - 0.077 13.3 4.1 0.26 11.6 4.1 1.9 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 14 Glyco_transf_8C PF08437.10 GBG67885.1 - 0.098 12.8 2.4 4.6 7.4 0.0 3.0 4 0 0 4 4 4 0 Glycosyl transferase family 8 C-terminal PSD4 PF07631.11 GBG67885.1 - 1.3 9.6 4.2 0.61 10.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) RVT_1 PF00078.27 GBG67886.1 - 9.5e-08 31.8 0.0 0.0073 15.8 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF592 PF04574.13 GBG67886.1 - 0.11 12.3 0.0 6.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF592) S-AdoMet_synt_C PF02773.16 GBG67887.1 - 8.6e-65 216.9 0.2 1.8e-64 215.8 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GBG67887.1 - 1.4e-46 157.6 0.0 2.6e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG67887.1 - 3.8e-43 146.2 0.2 7.6e-43 145.2 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain RVT_1 PF00078.27 GBG67889.1 - 3.4e-32 111.8 0.1 5.4e-32 111.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG67889.1 - 1.6e-29 102.3 0.0 3e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67889.1 - 3.2e-29 100.9 0.0 7.2e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67889.1 - 1.6e-11 44.2 0.3 2.2e-10 40.5 0.0 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain PKD_channel PF08016.12 GBG67889.1 - 0.082 11.6 0.5 0.13 11.0 0.5 1.2 1 0 0 1 1 1 0 Polycystin cation channel Phage_GPO PF05929.11 GBG67889.1 - 0.23 11.1 0.0 0.47 10.0 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-CCHC_6 PF15288.6 GBG67890.1 - 0.00045 20.0 0.5 0.0015 18.3 0.5 1.9 1 0 0 1 1 1 1 Zinc knuckle CLIP1_ZNF PF16641.5 GBG67890.1 - 0.053 13.4 1.2 0.12 12.3 1.2 1.7 1 0 0 1 1 1 0 CLIP1 zinc knuckle DnaJ PF00226.31 GBG67891.1 - 4.1e-18 65.2 0.7 1.2e-17 63.8 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 GBG67891.1 - 9.6e-13 48.1 7.4 7.4e-06 26.1 0.0 3.1 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG67891.1 - 2.7e-10 40.3 0.3 5.4e-06 26.6 0.1 3.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67891.1 - 0.012 15.9 0.0 0.012 15.9 0.0 4.4 5 1 1 6 6 6 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PRCC PF10253.9 GBG67891.1 - 0.016 16.0 14.2 0.016 16.0 14.2 3.2 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting FAM60A PF15396.6 GBG67891.1 - 0.26 11.3 0.0 0.26 11.3 0.0 4.8 3 1 0 3 3 3 0 Protein Family FAM60A Macoilin PF09726.9 GBG67891.1 - 0.54 8.7 33.7 0.0054 15.4 25.1 1.8 2 0 0 2 2 2 0 Macoilin family Mucin PF01456.17 GBG67891.1 - 5.8 6.9 24.0 2.9 7.9 19.0 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3342 PF11822.8 GBG67892.1 - 3e-22 78.6 0.0 6.7e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C3HC4 PF00097.25 GBG67892.1 - 0.85 9.5 3.8 22 5.0 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.9 GBG67893.1 - 9.6e-28 96.4 10.6 1.6e-27 95.7 10.6 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.9 GBG67893.1 - 0.0042 17.6 14.9 0.21 12.2 11.2 2.5 1 1 1 2 2 2 2 Microtubule-associated protein CRIPT TackOD1 PF18551.1 GBG67893.1 - 0.33 10.6 7.7 0.62 9.7 7.7 1.4 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 GBG67893.1 - 0.44 10.6 10.8 0.83 9.7 10.8 1.4 1 0 0 1 1 1 0 zinc-ribbons TFIIF_alpha PF05793.12 GBG67893.1 - 0.46 9.0 52.4 0.0049 15.5 44.4 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4486 PF14858.6 GBG67896.1 - 5.8e-37 127.4 0.0 1.6e-29 102.9 0.0 3.1 2 1 1 3 3 3 3 Domain of unknown function (DUF4486) GST_N_3 PF13417.6 GBG67897.1 - 4.1e-08 33.5 0.0 9.9e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GBG67897.1 - 1.1e-07 32.1 0.0 0.00097 19.4 0.0 2.9 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GBG67897.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GBG67897.1 - 0.04 14.2 0.0 0.084 13.2 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GBG67897.1 - 0.16 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LTV PF04180.14 GBG67898.1 - 0.69 9.6 19.1 0.059 13.1 4.1 2.6 2 0 0 2 2 2 0 Low temperature viability protein KI67R PF08065.12 GBG67898.1 - 2.7 8.6 8.5 0.44 11.1 3.2 2.4 2 0 0 2 2 2 0 KI67R (NUC007) repeat TT_ORF1 PF02956.14 GBG67898.1 - 9.6 4.7 10.7 15 4.1 10.7 1.2 1 0 0 1 1 1 0 TT viral orf 1 DUF1325 PF07039.11 GBG67899.1 - 2.1e-32 112.0 0.2 4.3e-32 111.0 0.2 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain zf-CCHC PF00098.23 GBG67899.1 - 9e-08 31.9 2.6 2e-07 30.7 2.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Tudor_3 PF18115.1 GBG67899.1 - 0.0094 15.8 0.1 0.047 13.5 0.0 2.2 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 GBG67899.1 - 0.028 14.9 5.2 3.6 8.1 0.0 3.2 4 0 0 4 4 4 0 Agenet domain zf-CCHC_6 PF15288.6 GBG67899.1 - 0.076 12.9 0.4 0.21 11.5 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle LBR_tudor PF09465.10 GBG67899.1 - 0.13 12.1 0.7 6.4 6.7 0.1 2.5 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain RT_RNaseH_2 PF17919.1 GBG67900.1 - 2e-29 101.5 0.0 5.1e-29 100.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67900.1 - 2e-27 95.5 0.0 4.6e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67900.1 - 5.7e-25 88.1 0.1 9.1e-25 87.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG67900.1 - 0.064 13.0 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF2249 PF10006.9 GBG67900.1 - 0.11 12.4 0.0 3.5 7.5 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) Nop14 PF04147.12 GBG67900.1 - 5.4 5.1 20.2 8.6 4.4 20.2 1.2 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG67900.1 - 5.5 6.5 9.0 9.2 5.7 9.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RVT_1 PF00078.27 GBG67901.1 - 8.6e-33 113.7 0.1 1.5e-32 113.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67901.1 - 7.8e-19 67.6 0.0 2.4e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG67901.1 - 6.9e-07 29.1 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG67901.1 - 4.3e-06 27.3 0.0 4.3e-05 24.1 0.0 2.7 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH PF17917.1 GBG67901.1 - 4.3e-06 27.0 0.0 1.4e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG67901.1 - 0.00024 21.6 0.0 0.00093 19.7 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG67901.1 - 0.0004 20.2 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease TPR_8 PF13181.6 GBG67901.1 - 0.00091 19.3 0.1 3.3 8.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 GBG67901.1 - 0.0027 18.2 1.3 2.3 9.1 0.1 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG67901.1 - 0.004 17.1 1.0 3.5 8.0 0.1 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat HALZ PF02183.18 GBG67901.1 - 0.075 13.3 1.2 0.26 11.6 1.2 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper TPR_19 PF14559.6 GBG67901.1 - 0.12 12.9 10.0 23 5.6 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ZapB PF06005.12 GBG67901.1 - 0.24 11.8 2.9 2.7 8.5 2.9 2.9 1 0 0 1 1 1 0 Cell division protein ZapB TPR_12 PF13424.6 GBG67901.1 - 0.62 10.4 8.9 2.1 8.7 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 GBG67902.1 - 2e-36 124.9 5.5 3.2e-36 124.2 1.5 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 GBG67902.1 - 9.2e-21 74.3 0.0 6.5e-20 71.6 0.0 2.4 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 GBG67902.1 - 2.7e-11 43.0 0.0 5e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 GBG67902.1 - 0.0056 16.6 3.4 34 4.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF410 PF04190.13 GBG67902.1 - 0.02 14.7 0.1 0.09 12.6 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_12 PF13424.6 GBG67902.1 - 0.026 14.8 7.3 76 3.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG67902.1 - 0.12 11.8 6.7 0.17 11.3 4.2 2.3 2 2 0 2 2 2 0 MalT-like TPR region TPR_1 PF00515.28 GBG67902.1 - 0.32 10.9 5.3 26 4.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG67903.1 - 3.8e-27 95.2 0.1 6.5e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67903.1 - 1.4e-19 70.0 0.0 4.7e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67903.1 - 6.3e-17 61.4 0.5 2.3e-16 59.6 0.5 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain TPR_19 PF14559.6 GBG67903.1 - 2e-15 57.1 0.0 0.002 18.6 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG67903.1 - 1.2e-12 46.9 3.7 0.08 13.1 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 GBG67903.1 - 1.4e-12 47.1 2.3 0.0007 19.8 0.0 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat RT_RNaseH PF17917.1 GBG67903.1 - 4.2e-11 43.1 0.0 8.6e-09 35.6 0.0 2.7 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase TPR_16 PF13432.6 GBG67903.1 - 1.3e-08 35.3 14.4 0.0029 18.2 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GBG67903.1 - 3.5e-07 30.5 20.4 0.11 13.4 0.3 8.5 4 3 4 8 8 7 3 Tetratricopeptide repeat rve PF00665.26 GBG67903.1 - 4.5e-06 26.8 0.0 1.5e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain TPR_8 PF13181.6 GBG67903.1 - 4.8e-06 26.4 0.0 5.5 7.5 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 GBG67903.1 - 0.0001 21.6 0.3 0.0001 21.6 0.3 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG67903.1 - 0.0012 18.6 1.5 32 4.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG67903.1 - 0.0021 18.6 1.6 17 6.3 0.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG67903.1 - 0.0029 17.9 19.0 1.6 9.1 0.1 6.5 5 2 2 7 7 6 2 Tetratricopeptide repeat Chromo PF00385.24 GBG67903.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain G0-G1_switch_2 PF15103.6 GBG67903.1 - 1.5 9.3 4.1 2.8 8.4 0.0 2.9 2 0 0 2 2 2 0 G0/G1 switch protein 2 Ldh_1_C PF02866.18 GBG67904.1 - 1.3e-49 168.4 0.0 1.9e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GBG67904.1 - 1.6e-46 157.9 0.0 2.3e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GBG67904.1 - 0.00045 19.3 0.0 0.00066 18.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PPR_2 PF13041.6 GBG67905.1 - 6.7e-56 186.3 6.6 7.3e-15 54.9 0.0 12.1 4 3 9 13 13 13 12 PPR repeat family PPR PF01535.20 GBG67905.1 - 5.9e-48 157.8 29.9 1.8e-06 27.8 0.1 14.5 14 0 0 14 14 14 10 PPR repeat PPR_3 PF13812.6 GBG67905.1 - 4e-43 145.3 0.0 7.9e-08 32.3 0.0 9.4 7 2 1 9 9 9 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG67905.1 - 2.8e-29 100.5 4.0 1.4e-06 27.9 0.0 10.8 12 0 0 12 12 12 4 PPR repeat PPR_long PF17177.4 GBG67905.1 - 1.9e-21 76.4 0.9 1.1e-09 37.9 0.4 4.1 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP Exog_C PF18026.1 GBG67905.1 - 0.013 15.5 0.5 17 5.5 0.1 4.4 5 0 0 5 5 5 0 Endo/exonuclease (EXOG) C-terminal domain DUF2851 PF11013.8 GBG67905.1 - 0.058 12.4 0.0 0.45 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2851) LNS2 PF08235.13 GBG67906.1 - 2.8e-91 305.0 0.0 4.2e-91 304.4 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 GBG67906.1 - 2.5e-22 78.7 0.1 5.4e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 GBG67906.1 - 1.2e-15 57.4 0.0 3.6e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Gluconate_2-dh3 PF13618.6 GBG67908.1 - 3.4 7.9 5.9 13 6.1 5.9 2.0 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 TSC22 PF01166.18 GBG67908.1 - 5.5 7.4 12.2 1.4 9.2 4.2 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family RVT_1 PF00078.27 GBG67910.1 - 7.9e-28 97.5 0.0 1.2e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG67912.1 - 3.1e-09 37.1 3.8 3.8e-09 36.8 0.2 2.7 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67912.1 - 0.028 14.7 0.1 0.07 13.4 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_S10 PF00450.22 GBG67914.1 - 2.3e-108 363.3 0.0 4.7e-49 167.9 0.0 3.0 3 0 0 3 3 3 3 Serine carboxypeptidase Cyt_b-c1_8 PF10890.8 GBG67916.1 - 1.3e-35 121.6 0.1 1.5e-35 121.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 UcrQ PF02939.16 GBG67916.1 - 1.6e-06 27.9 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 UcrQ family Arv1 PF04161.13 GBG67917.1 - 8.4e-41 140.4 8.2 3e-40 138.6 8.2 1.9 1 1 0 1 1 1 1 Arv1-like family DZR PF12773.7 GBG67917.1 - 0.048 13.7 0.4 0.08 13.0 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon Acetyltransf_17 PF17668.1 GBG67917.1 - 0.13 13.1 0.0 0.32 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gpr1_Fun34_YaaH PF01184.19 GBG67918.1 - 0.0019 17.8 0.5 0.0028 17.3 0.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family LtrA PF06772.11 GBG67918.1 - 0.014 14.6 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Spt20 PF12090.8 GBG67918.1 - 2.6 7.6 8.0 3.8 7.1 8.0 1.1 1 0 0 1 1 1 0 Spt20 family CHD5 PF04420.14 GBG67919.1 - 0.083 12.7 2.0 0.16 11.8 2.0 1.5 1 0 0 1 1 1 0 CHD5-like protein BAF1_ABF1 PF04684.13 GBG67919.1 - 4.4 6.2 8.1 6.3 5.7 8.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RT_RNaseH PF17917.1 GBG67920.1 - 8.9e-31 106.3 0.1 1.5e-29 102.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67920.1 - 3.1e-29 101.0 0.0 3.2e-28 97.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67920.1 - 4.2e-19 68.4 0.4 4.2e-19 68.4 0.4 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG67920.1 - 3.5e-16 59.5 0.0 1.1e-14 54.7 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG67920.1 - 0.0018 18.4 0.0 0.0056 16.9 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG67920.1 - 0.2 11.3 0.1 0.4 10.2 0.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase LEA_4 PF02987.16 GBG67921.1 - 2.4e-11 43.5 44.2 8.8e-07 28.9 16.4 4.0 2 1 1 4 4 4 3 Late embryogenesis abundant protein Apolipoprotein PF01442.18 GBG67921.1 - 1.2e-07 31.9 30.0 0.00018 21.4 17.2 2.0 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GBG67921.1 - 0.0087 16.6 32.6 50 4.5 19.0 3.7 1 1 1 2 2 2 0 YtxH-like protein PuR_N PF09182.10 GBG67921.1 - 0.024 14.6 0.2 0.29 11.1 0.0 2.2 1 1 1 2 2 2 0 Bacterial purine repressor, N-terminal DUF883 PF05957.13 GBG67921.1 - 0.2 12.3 29.3 2.7 8.6 4.4 3.4 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF1451 PF07295.11 GBG67921.1 - 0.69 9.9 18.3 0.069 13.2 10.4 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF659 PF04937.15 GBG67922.1 - 1e-14 54.7 0.0 1.5e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) LEA_4 PF02987.16 GBG67923.1 - 8.4e-09 35.4 44.1 3.2e-07 30.3 15.0 4.0 4 1 0 4 4 4 3 Late embryogenesis abundant protein Apolipoprotein PF01442.18 GBG67923.1 - 2.5e-07 30.8 28.3 6.8e-07 29.4 28.4 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GBG67923.1 - 0.0015 19.0 30.8 1.8e+04 -8.5 30.8 3.5 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 GBG67923.1 - 0.013 16.1 29.5 0.12 12.9 4.1 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) CAP160 PF07918.11 GBG67923.1 - 0.044 13.5 0.1 0.044 13.5 0.1 2.6 3 0 0 3 3 3 0 CAP160 repeat DUF1451 PF07295.11 GBG67923.1 - 0.26 11.3 18.7 0.019 15.0 8.5 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain Prominin PF05478.11 GBG67923.1 - 9.3 4.1 9.8 11 3.8 9.8 1.0 1 0 0 1 1 1 0 Prominin LEA_4 PF02987.16 GBG67924.1 - 2.9e-07 30.5 48.2 4.4e-06 26.7 17.2 4.1 2 1 1 4 4 4 4 Late embryogenesis abundant protein Apolipoprotein PF01442.18 GBG67924.1 - 6.9e-07 29.3 29.2 1.5e-06 28.2 29.2 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GBG67924.1 - 0.011 16.2 31.8 1.8e+04 -8.5 31.8 3.5 1 1 0 1 1 1 0 YtxH-like protein UDPG_MGDP_dh PF00984.19 GBG67924.1 - 0.017 15.3 0.6 0.043 14.0 0.6 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain PuR_N PF09182.10 GBG67924.1 - 0.024 14.6 0.6 0.13 12.2 0.0 2.4 1 1 2 3 3 3 0 Bacterial purine repressor, N-terminal DUF883 PF05957.13 GBG67924.1 - 0.043 14.4 30.3 0.86 10.2 3.5 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) YgaB PF14182.6 GBG67924.1 - 0.13 12.7 0.2 0.13 12.7 0.2 2.5 1 1 1 2 2 2 0 YgaB-like protein DUF1451 PF07295.11 GBG67924.1 - 2.2 8.3 19.0 0.083 12.9 8.9 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain WD40 PF00400.32 GBG67926.1 - 8.7e-11 42.2 9.6 0.24 12.3 0.0 8.2 9 0 0 9 9 9 3 WD domain, G-beta repeat HELP PF03451.14 GBG67926.1 - 0.031 14.1 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 HELP motif EF-hand_9 PF14658.6 GBG67926.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain F-box-like PF12937.7 GBG67927.1 - 7.9e-06 25.7 0.2 1.6e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG67927.1 - 1.6e-05 24.7 1.9 0.00031 20.5 1.9 2.6 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG67928.1 - 6.9e-06 25.9 0.2 1.4e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG67928.1 - 1.3e-05 25.0 1.9 0.00028 20.7 1.9 2.6 1 1 0 1 1 1 1 F-box domain RT_RNaseH_2 PF17919.1 GBG67931.1 - 3.9e-26 91.0 0.0 7.9e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67931.1 - 1.1e-23 83.5 0.0 3.5e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67931.1 - 3.4e-16 59.4 0.0 5.5e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG67932.1 - 6.1e-05 22.9 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) S-antigen PF05756.11 GBG67932.1 - 0.08 13.3 0.4 0.14 12.5 0.4 1.4 1 0 0 1 1 1 0 S-antigen protein Thioredoxin PF00085.20 GBG67933.1 - 1.6e-19 69.8 0.0 2.1e-08 34.1 0.2 5.0 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.6 GBG67933.1 - 1.7e-08 34.6 0.0 0.38 10.6 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG67933.1 - 0.00011 22.5 0.1 0.44 10.9 0.0 4.2 4 1 0 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GBG67933.1 - 0.002 18.6 0.0 2.1 8.8 0.0 3.6 3 1 0 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 GBG67933.1 - 0.038 14.0 0.0 4.9 7.2 0.0 3.2 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 GBG67933.1 - 0.18 11.1 0.2 7.5 5.8 0.0 3.1 3 1 1 4 4 4 0 OST3 / OST6 family, transporter family E7 PF00527.18 GBG67933.1 - 1.6 9.0 0.0 1.6 9.0 0.0 2.8 1 1 1 2 2 2 0 E7 protein, Early protein TraF PF13728.6 GBG67933.1 - 1.6 8.5 0.0 1.6 8.5 0.0 3.6 5 0 0 5 5 5 0 F plasmid transfer operon protein Ion_trans PF00520.31 GBG67934.1 - 1.4e-10 40.9 5.4 4.3e-06 26.2 0.4 2.2 1 1 1 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 GBG67934.1 - 1e-05 25.5 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain IQ PF00612.27 GBG67934.1 - 0.053 13.3 2.7 0.15 11.9 2.7 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif UPF0114 PF03350.16 GBG67934.1 - 0.099 12.9 0.2 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 O-FucT PF10250.9 GBG67936.1 - 4.3e-59 200.9 0.0 5.6e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PPP4R2 PF09184.11 GBG67937.1 - 3.7 7.1 15.8 5.2 6.6 15.8 1.2 1 0 0 1 1 1 0 PPP4R2 Branch PF02485.21 GBG67938.1 - 3.6e-44 151.1 0.1 5.5e-44 150.5 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ser_hydrolase PF06821.13 GBG67940.1 - 0.0081 16.0 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase E1_DerP2_DerF2 PF02221.15 GBG67941.1 - 2.6e-20 73.2 0.0 3.1e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 ML domain Abhydrolase_6 PF12697.7 GBG67941.1 - 0.12 13.0 0.0 0.13 12.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1929 PF09118.11 GBG67941.1 - 0.16 12.3 0.7 12 6.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) adh_short PF00106.25 GBG67942.1 - 5.2e-27 94.6 0.1 1e-08 34.9 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 GBG67942.1 - 6.3e-13 48.8 0.0 0.00097 18.8 0.0 3.2 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG67942.1 - 0.00027 20.9 0.1 0.00049 20.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GBG67942.1 - 0.0082 15.6 0.1 0.031 13.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GBG67942.1 - 0.18 11.7 0.5 0.35 10.7 0.5 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DUF659 PF04937.15 GBG67943.1 - 2.3e-47 160.6 0.0 2.6e-24 85.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG67943.1 - 1.2e-13 50.7 0.5 8.3e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 hAT family C-terminal dimerisation region Acyl-CoA_dh_2 PF08028.11 GBG67944.1 - 1 9.6 5.8 2.7 8.3 2.3 2.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Ppx-GppA PF02541.16 GBG67945.1 - 2.2e-34 119.2 0.0 1.4e-18 67.4 0.0 2.4 2 1 0 2 2 2 2 Ppx/GppA phosphatase family RT_RNaseH PF17917.1 GBG67946.1 - 1.8e-30 105.3 0.0 4.4e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67946.1 - 1.6e-29 101.9 0.0 3.6e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67946.1 - 1.5e-19 69.8 0.4 3.3e-19 68.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG67946.1 - 0.00048 20.3 0.0 0.0017 18.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG67946.1 - 0.0012 19.0 0.1 0.003 17.7 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger TRAUB PF08164.12 GBG67947.1 - 6.4e-08 33.0 0.1 1.4e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 GBG67947.1 - 0.0013 19.4 0.0 0.0023 18.6 0.0 1.5 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor RVT_1 PF00078.27 GBG67948.1 - 2.1e-28 99.3 0.0 3.3e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67948.1 - 1.1e-22 79.9 0.0 3e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67948.1 - 4.4e-12 46.2 0.0 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG67948.1 - 5.1e-08 33.1 0.0 1.4e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG67948.1 - 7.5e-07 29.6 0.0 1.4e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG67948.1 - 8.4e-07 29.5 0.0 1.8e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG67948.1 - 1.4e-06 28.1 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67948.1 - 0.0008 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG67948.1 - 0.0019 18.1 0.2 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AATF-Che1 PF13339.6 GBG67949.1 - 2.8e-15 57.2 0.0 2.8e-15 57.2 0.0 2.6 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor SDA1 PF05285.12 GBG67949.1 - 0.008 15.6 16.4 0.0089 15.5 16.4 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG67949.1 - 0.11 10.8 15.1 0.13 10.5 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein MRI PF15325.6 GBG67949.1 - 4.2 8.5 16.3 7.3 7.7 6.3 2.3 1 1 1 2 2 2 0 Modulator of retrovirus infection Pinin_SDK_memA PF04696.13 GBG67950.1 - 1 9.4 23.9 1.2 9.2 23.9 1.0 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DDRGK PF09756.9 GBG67950.1 - 1.3 8.6 23.1 1.4 8.5 23.1 1.0 1 0 0 1 1 1 0 DDRGK domain Eapp_C PF10238.9 GBG67950.1 - 1.9 8.5 8.0 2.1 8.4 8.0 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein HA2 PF04408.23 GBG67950.1 - 2.4 8.5 4.3 2.8 8.3 4.3 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) Presenilin PF01080.17 GBG67950.1 - 2.5 6.8 6.6 2.6 6.7 6.6 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GBG67950.1 - 2.8 7.7 10.7 2.8 7.7 10.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Merozoite_SPAM PF07133.11 GBG67950.1 - 3.1 7.8 20.9 3.4 7.6 20.9 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Connexin PF00029.19 GBG67950.1 - 3.2 7.5 8.0 3.4 7.3 8.0 1.0 1 0 0 1 1 1 0 Connexin RPN2_C PF18004.1 GBG67950.1 - 4.2 7.3 11.4 4.7 7.1 11.4 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NARP1 PF12569.8 GBG67950.1 - 4.9 5.9 11.0 5.2 5.9 11.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2828 PF11443.8 GBG67950.1 - 5.6 4.9 8.0 5.5 5.0 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) V_ATPase_I PF01496.19 GBG67950.1 - 8 4.2 6.6 8.3 4.2 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP-synt PF00231.19 GBG67951.1 - 1.6e-87 293.8 0.1 1.8e-87 293.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase Ppx-GppA PF02541.16 GBG67952.1 - 1.1e-46 159.5 0.0 2.2e-24 86.4 0.0 2.7 2 1 0 2 2 2 2 Ppx/GppA phosphatase family YebO PF13974.6 GBG67953.1 - 0.87 9.7 9.2 4 7.6 0.9 3.1 2 0 0 2 2 2 0 YebO-like protein Histone PF00125.24 GBG67954.1 - 1.4e-23 83.7 0.2 1.4e-23 83.7 0.2 3.0 1 1 2 4 4 4 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.13 GBG67954.1 - 0.049 13.6 10.6 0.12 12.4 10.6 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_4 PF13894.6 GBG67955.1 - 0.00012 22.6 6.2 0.25 12.3 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GBG67955.1 - 0.018 15.5 5.5 0.16 12.5 1.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GBG67955.1 - 0.045 14.1 4.7 0.3 11.4 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.14 GBG67955.1 - 0.082 12.8 1.8 0.51 10.2 0.1 2.1 1 1 1 2 2 2 0 Rad50 zinc hook motif LIM PF00412.22 GBG67955.1 - 0.13 12.5 2.7 0.23 11.7 2.7 1.3 1 0 0 1 1 1 0 LIM domain DUF629 PF04780.12 GBG67955.1 - 1.2 7.6 3.2 1.9 6.9 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) PyrI_C PF02748.15 GBG67955.1 - 9.7 6.2 8.6 3.4 7.6 1.8 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF604 PF04646.12 GBG67956.1 - 1.1e-67 228.2 0.0 4.5e-66 222.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.16 GBG67956.1 - 5e-14 52.3 0.0 8.6e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Fringe-like ABC2_membrane_3 PF12698.7 GBG67957.1 - 0.32 10.1 0.1 0.41 9.7 0.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DDE_Tnp_4 PF13359.6 GBG67958.1 - 4e-18 65.6 0.0 1.3e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67958.1 - 2.8e-08 33.6 0.0 4.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67958.1 - 0.014 15.0 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG67959.1 - 2e-08 34.5 0.8 4e-08 33.5 0.8 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG67959.1 - 0.00079 19.4 0.2 0.0022 18.0 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67959.1 - 0.012 16.0 0.2 0.047 14.0 0.2 2.0 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Syntaxin-5_N PF11416.8 GBG67960.1 - 0.036 13.3 1.6 0.14 11.5 0.5 2.1 2 0 0 2 2 2 0 Syntaxin-5 N-terminal, Sly1p-binding domain CAF1A PF12253.8 GBG67960.1 - 0.34 11.1 8.9 1.5 9.0 8.9 2.1 1 1 0 1 1 1 0 Chromatin assembly factor 1 subunit A Ferritin PF00210.24 GBG67961.1 - 1.2e-08 35.0 0.0 4.4e-08 33.2 0.0 2.1 3 1 0 3 3 3 1 Ferritin-like domain PCAF_N PF06466.11 GBG67962.1 - 0.019 14.5 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain DDE_Tnp_4 PF13359.6 GBG67963.1 - 3e-17 62.7 0.0 8e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG67963.1 - 3.7e-08 33.2 0.0 6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG67963.1 - 0.0041 16.8 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Nbl1_Borealin_N PF10444.9 GBG67964.1 - 0.18 11.4 0.4 0.62 9.8 0.4 1.8 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal zf-CCHC PF00098.23 GBG67966.1 - 0.0012 18.9 0.2 0.0022 18.0 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle CCDC106 PF15794.5 GBG67966.1 - 0.0068 16.2 3.5 0.0094 15.7 0.4 2.1 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 106 Prefoldin_2 PF01920.20 GBG67966.1 - 0.017 15.1 0.6 0.017 15.1 0.6 2.5 2 1 0 2 2 2 0 Prefoldin subunit FinO_N PF12602.8 GBG67966.1 - 0.028 14.7 0.4 6 7.3 0.0 2.6 2 0 0 2 2 2 0 Fertility inhibition protein N terminal NEMP PF10225.9 GBG67966.1 - 1.6 8.3 3.1 13 5.4 0.6 2.1 2 0 0 2 2 2 0 NEMP family Vps54_N PF10475.9 GBG67966.1 - 2.7 7.2 5.6 6.5 6.0 0.2 2.8 3 0 0 3 3 3 0 Vacuolar-sorting protein 54, of GARP complex OmpH PF03938.14 GBG67966.1 - 2.9 8.2 11.0 0.2 12.0 1.3 2.8 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Pectinesterase PF01095.19 GBG67967.1 - 3.4e-67 226.3 0.3 4.6e-67 225.8 0.3 1.2 1 0 0 1 1 1 1 Pectinesterase HIG_1_N PF04588.13 GBG67969.1 - 0.059 13.6 0.3 0.1 12.8 0.3 1.3 1 0 0 1 1 1 0 Hypoxia induced protein conserved region LRR_8 PF13855.6 GBG67971.1 - 1.9e-09 37.1 14.0 0.0006 19.5 0.1 5.5 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 GBG67971.1 - 5.5e-08 33.0 15.0 0.037 14.5 0.4 5.6 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG67971.1 - 2.1e-05 24.2 1.2 19 5.7 0.0 5.7 5 0 0 5 5 5 1 Leucine Rich repeat DUF4690 PF15756.5 GBG67971.1 - 0.0026 18.3 0.0 0.013 16.1 0.0 2.2 1 0 0 1 1 1 1 Small Novel Rich in Cartilage VSP PF03302.13 GBG67971.1 - 0.021 13.7 0.4 0.021 13.7 0.4 2.3 3 0 0 3 3 3 0 Giardia variant-specific surface protein LRR_1 PF00560.33 GBG67971.1 - 0.035 14.6 10.5 65 4.7 0.0 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat MHYT PF03707.16 GBG67971.1 - 3.8 7.7 8.3 19 5.5 0.6 2.6 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat DUF659 PF04937.15 GBG67972.1 - 5.4e-32 110.8 0.0 9.8e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG67973.1 - 3.5e-06 27.3 0.3 5.5e-06 26.7 0.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG67973.1 - 0.049 13.9 0.2 0.093 13.1 0.2 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG67973.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TFIIA PF03153.13 GBG67973.1 - 2.7 7.9 21.1 4.5 7.2 21.1 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rab_bind PF16704.5 GBG67974.1 - 0.002 18.1 0.3 0.12 12.4 0.0 2.6 2 0 0 2 2 2 2 Rab binding domain DEAD PF00270.29 GBG67975.1 - 1.5e-49 168.2 0.0 1.3e-48 165.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG67975.1 - 8.8e-28 96.9 0.0 2.4e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RVT_1 PF00078.27 GBG67976.1 - 2.8e-13 49.9 0.0 4.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67976.1 - 2.7e-11 43.4 0.0 5.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Na_trans_assoc PF06512.13 GBG67976.1 - 0.051 13.9 6.5 0.068 13.4 6.5 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2201_N PF13203.6 GBG67976.1 - 0.27 10.8 2.4 0.41 10.2 2.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Branch PF02485.21 GBG67977.1 - 3.2e-58 197.2 0.0 4.5e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Toxin_8 PF07365.12 GBG67977.1 - 0.14 12.4 0.1 0.79 9.9 0.0 2.2 2 0 0 2 2 2 0 Alpha conotoxin precursor DUF659 PF04937.15 GBG67979.1 - 2.3e-27 95.7 0.0 4.3e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG67979.1 - 0.0044 16.8 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NR_Repeat PF14046.6 GBG67979.1 - 0.036 14.2 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 Nuclear receptor repeat RT_RNaseH PF17917.1 GBG67980.1 - 5.1e-28 97.4 0.0 2.4e-27 95.3 0.0 2.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67980.1 - 2e-27 95.1 0.0 7.3e-27 93.3 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG67982.1 - 4.2e-26 90.9 0.0 1.2e-25 89.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67982.1 - 1.7e-24 86.1 0.0 4.6e-24 84.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67982.1 - 7.3e-18 64.9 0.0 1.5e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG67982.1 - 3.4e-16 59.1 0.5 9.2e-16 57.7 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG67982.1 - 2.5e-07 31.2 0.0 5.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67982.1 - 1e-06 29.2 0.0 2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67982.1 - 8e-06 25.7 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG67982.1 - 2e-05 24.8 0.0 8.1e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG67982.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG67982.1 - 0.0096 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG67983.1 - 3.1e-32 110.6 0.0 7e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67983.1 - 4.5e-31 107.2 0.1 9.2e-31 106.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67983.1 - 3e-17 62.5 0.5 5.5e-17 61.6 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG67983.1 - 0.00054 20.2 0.0 0.0024 18.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG67983.1 - 0.067 13.4 0.0 0.067 13.4 0.0 1.8 2 0 0 2 2 2 0 H2C2 zinc finger CBP_CCPA PF17040.5 GBG67983.1 - 0.084 13.5 0.5 0.21 12.2 0.5 1.7 1 0 0 1 1 1 0 Cellulose-complementing protein A ATG16 PF08614.11 GBG67983.1 - 0.68 10.1 10.8 1.3 9.2 10.8 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Dppa2_A PF14049.6 GBG67983.1 - 0.9 9.7 10.6 3 8.1 4.0 2.5 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates FAM199X PF15814.5 GBG67983.1 - 4.7 6.2 7.1 7.4 5.5 7.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X rve PF00665.26 GBG67984.1 - 6.3e-14 52.2 0.0 1.5e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG67984.1 - 0.0026 17.5 0.1 0.0066 16.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) rve_3 PF13683.6 GBG67984.1 - 0.063 13.1 0.2 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG67985.1 - 3.3e-28 97.6 0.0 8.8e-27 93.1 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67985.1 - 1.1e-25 89.9 0.0 6.6e-25 87.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67985.1 - 2.2e-19 69.3 0.3 5.6e-19 68.0 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG67985.1 - 1.5e-09 38.0 0.0 4e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG67985.1 - 0.00028 21.5 0.0 0.00052 20.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG67985.1 - 0.00035 21.1 0.0 0.00065 20.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG67985.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG67985.1 - 0.0029 17.4 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG67985.1 - 0.044 14.0 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG67985.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG67986.1 - 1.3e-28 100.0 0.1 4.6e-28 98.3 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG67986.1 - 1.1e-25 89.5 0.0 3.4e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67986.1 - 3e-23 82.1 0.0 8.7e-23 80.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG67986.1 - 6e-18 64.7 1.0 1.2e-17 63.7 1.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG67986.1 - 0.0064 16.7 5.9 0.026 14.8 0.0 4.1 4 0 0 4 4 4 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG67986.1 - 0.028 14.7 0.0 0.076 13.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 GBG67986.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DNA_topoisoIV PF00521.20 GBG67986.1 - 0.41 9.5 6.6 4.6 6.0 0.0 2.3 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A DUF3984 PF13136.6 GBG67987.1 - 0.0034 16.8 26.6 0.0053 16.2 26.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) PPP4R2 PF09184.11 GBG67987.1 - 0.064 12.8 19.2 0.083 12.5 19.2 1.1 1 0 0 1 1 1 0 PPP4R2 Transformer PF06495.11 GBG67987.1 - 0.72 9.9 26.0 1.2 9.2 26.0 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein ADP_ribosyl_GH PF03747.14 GBG67987.1 - 2.2 8.0 22.9 2.4 7.8 22.9 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase SWIRM-assoc_2 PF16496.5 GBG67987.1 - 9.4 5.0 12.2 11 4.7 12.2 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RT_RNaseH_2 PF17919.1 GBG67988.1 - 4.2e-26 90.9 0.0 8.7e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67988.1 - 6.4e-25 87.5 0.0 1.2e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG67988.1 - 3.6e-09 36.5 0.1 1.5e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG67988.1 - 1.3e-05 25.3 0.1 4.6e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG67989.1 - 0.0051 17.0 0.1 0.0051 17.0 0.1 3.0 3 1 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG67989.1 - 0.012 15.4 1.2 0.043 13.6 1.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RVT_1 PF00078.27 GBG67990.1 - 8.6e-13 48.3 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG67990.1 - 0.73 8.1 13.2 1.1 7.5 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG67990.1 - 0.73 8.0 17.8 1.1 7.4 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family Usp PF00582.26 GBG67990.1 - 0.94 10.0 6.7 2.8 8.5 6.7 1.8 1 0 0 1 1 1 0 Universal stress protein family Cwf_Cwc_15 PF04889.12 GBG67990.1 - 2 8.1 16.5 32 4.1 0.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG67990.1 - 6.8 6.0 19.2 12 5.2 19.2 1.3 1 0 0 1 1 1 0 SDA1 LRR_4 PF12799.7 GBG67991.1 - 2.3e-17 62.8 14.4 0.00024 21.4 0.1 4.9 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG67991.1 - 4.7e-12 45.5 17.7 0.00013 21.7 1.1 4.4 1 1 4 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 GBG67991.1 - 1.5e-09 37.1 14.5 0.31 11.2 0.6 6.6 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 GBG67991.1 - 7.5e-07 28.8 19.1 0.23 12.1 0.2 7.5 8 1 1 9 9 9 2 Leucine Rich Repeat RT_RNaseH_2 PF17919.1 GBG67991.1 - 2.7e-05 24.1 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG67991.1 - 0.00013 22.2 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Transgly_assoc PF04226.13 GBG67991.1 - 0.29 11.4 0.7 1.1 9.5 0.1 2.1 2 0 0 2 2 2 0 Transglycosylase associated protein Mlf1IP PF10248.9 GBG67993.1 - 0.12 12.3 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Peptidase_C26 PF07722.13 GBG67994.1 - 1e-36 126.7 0.1 3.3e-21 76.1 1.7 3.7 2 2 0 2 2 2 2 Peptidase C26 GATase PF00117.28 GBG67994.1 - 7.4e-11 42.2 3.1 1.7e-07 31.2 1.0 2.5 2 0 0 2 2 2 2 Glutamine amidotransferase class-I TERB2 PF15101.6 GBG67994.1 - 0.14 12.2 8.4 0.34 10.9 8.4 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 GBG67994.1 - 0.21 11.6 2.9 0.11 12.5 0.3 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 GBG67994.1 - 0.34 9.0 8.2 0.54 8.3 8.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.11 GBG67994.1 - 0.5 9.7 2.6 0.95 8.8 2.6 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Spem1 PF15670.5 GBG67994.1 - 1.1 8.7 8.6 0.11 12.1 3.5 1.9 2 0 0 2 2 2 0 Spermatid maturation protein 1 SLC12 PF03522.15 GBG67994.1 - 1.2 8.1 6.6 2.2 7.2 6.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Ndc1_Nup PF09531.10 GBG67994.1 - 1.6 7.3 6.3 2.5 6.7 6.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.6 GBG67994.1 - 3.3 7.0 6.8 7.4 5.8 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Apc15p PF05841.11 GBG67994.1 - 3.7 8.4 15.9 0.35 11.7 10.5 2.2 2 0 0 2 2 2 0 Apc15p protein Spt20 PF12090.8 GBG67994.1 - 4.7 6.8 25.2 8.3 6.0 25.2 1.4 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 GBG67994.1 - 6.3 5.4 10.7 14 4.3 10.7 1.5 1 0 0 1 1 1 0 Presenilin Phosphoesterase PF04185.14 GBG67997.1 - 1.1e-95 320.8 0.0 1.5e-95 320.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoesterase family DUF445 PF04286.12 GBG67997.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Cellulase PF00150.18 GBG67999.1 - 1.2e-07 31.4 0.9 0.001 18.5 0.3 2.1 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) NUP PF06516.11 GBG67999.1 - 0.12 11.6 0.1 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Purine nucleoside permease (NUP) zf-CCHC PF00098.23 GBG68000.1 - 0.00018 21.4 5.3 0.00039 20.4 5.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG68000.1 - 0.048 13.6 2.9 0.15 12.0 2.9 1.9 1 0 0 1 1 1 0 Zinc knuckle Mem_trans PF03547.18 GBG68000.1 - 1.2 7.4 3.5 1.7 6.9 3.5 1.1 1 0 0 1 1 1 0 Membrane transport protein Vfa1 PF08432.10 GBG68000.1 - 1.9 8.8 21.8 2.9 8.2 21.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PARP PF00644.20 GBG68001.1 - 7.9e-50 169.2 1.6 1.1e-49 168.7 0.0 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain zf-PARP PF00645.18 GBG68001.1 - 3.3e-36 124.0 0.7 2.2e-16 60.5 0.1 3.2 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PARP_reg PF02877.14 GBG68001.1 - 2.9e-35 121.3 0.0 6.1e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 GBG68001.1 - 1.1e-17 63.9 0.6 4.5e-17 61.9 0.6 2.2 1 0 0 1 1 1 1 WGR domain PADR1 PF08063.12 GBG68001.1 - 3.4e-17 62.0 1.8 3.4e-17 62.0 1.8 2.0 2 0 0 2 2 2 1 PADR1 (NUC008) domain BRCT PF00533.26 GBG68001.1 - 2.3e-11 43.9 0.0 7.8e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GBG68001.1 - 2.8e-06 27.6 0.0 6.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain SAP PF02037.27 GBG68001.1 - 0.11 12.2 0.1 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 SAP domain KAR9 PF08580.10 GBG68003.1 - 0.27 9.7 0.3 0.35 9.3 0.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RT_RNaseH_2 PF17919.1 GBG68005.1 - 2.1e-24 85.4 0.0 3.9e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68005.1 - 4.7e-22 78.3 0.0 1.4e-21 76.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68005.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG68007.1 - 4.4e-23 82.0 0.1 6.4e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG68007.1 - 1.9e-05 25.2 0.0 4.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68007.1 - 0.00086 19.8 0.0 0.0016 19.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG68007.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG68007.1 - 0.0078 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF659 PF04937.15 GBG68009.1 - 8.3e-21 74.4 0.0 1.3e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pkinase_Tyr PF07714.17 GBG68010.1 - 1.7e-39 135.7 0.0 5.2e-39 134.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG68010.1 - 3.2e-36 125.0 0.0 4.6e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG68010.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4175 PF13779.6 GBG68010.1 - 0.085 10.8 0.5 0.12 10.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RVT_1 PF00078.27 GBG68012.1 - 1.3e-11 44.5 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG68012.1 - 0.01 16.5 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4360 PF14273.6 GBG68013.1 - 8.9e-33 113.6 0.2 1e-32 113.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF659 PF04937.15 GBG68014.1 - 1.1e-12 48.1 0.0 1.8e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG68014.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG68015.1 - 1.6e-21 76.8 0.0 2.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG68015.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DEAD PF00270.29 GBG68017.1 - 2.7e-50 170.6 0.0 1.5e-24 86.8 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG68017.1 - 2.4e-13 50.4 0.0 4.1e-12 46.4 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 GBG68017.1 - 0.00015 21.2 0.1 0.13 11.5 0.0 3.0 3 0 0 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit BNR PF02012.20 GBG68018.1 - 1.2 9.4 3.0 4 7.8 0.8 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat DUF4360 PF14273.6 GBG68019.1 - 3.8e-41 140.9 1.4 4.4e-41 140.7 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG68020.1 - 2.2e-41 141.7 2.1 2.6e-41 141.5 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG68021.1 - 1.2e-45 155.5 0.3 1.4e-45 155.3 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG68022.1 - 9.1e-41 139.7 2.2 1.1e-40 139.4 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Myb_DNA-bind_4 PF13837.6 GBG68023.1 - 5.1e-09 36.4 0.4 8.7e-09 35.6 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG68023.1 - 0.005 17.0 0.2 0.014 15.5 0.2 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG68023.1 - 0.024 14.7 0.5 0.042 13.9 0.5 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG68023.1 - 0.2 11.9 0.7 0.52 10.6 0.1 2.0 2 1 0 2 2 2 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG68024.1 - 1.3e-29 103.0 0.0 1.8e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68024.1 - 1.8e-16 60.3 0.0 2.6e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68024.1 - 1.4e-05 24.9 2.7 0.00084 19.0 2.7 2.7 1 1 0 1 1 1 1 Transposase DDE domain DUF4360 PF14273.6 GBG68025.1 - 4.9e-41 140.6 1.5 5.6e-41 140.4 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SR-25 PF10500.9 GBG68026.1 - 0.00022 20.9 11.5 0.00026 20.7 11.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 GBG68026.1 - 0.0034 15.8 21.4 0.0038 15.6 21.4 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop53 PF07767.11 GBG68026.1 - 0.015 14.7 24.6 0.018 14.4 24.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Dehydrin PF00257.19 GBG68026.1 - 0.18 12.4 6.5 0.23 12.0 6.2 1.4 1 1 0 1 1 1 0 Dehydrin CCDC106 PF15794.5 GBG68026.1 - 0.64 9.7 17.5 0.78 9.4 17.0 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 PI3K_1B_p101 PF10486.9 GBG68026.1 - 1 7.0 8.1 1.1 7.0 8.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Merozoite_SPAM PF07133.11 GBG68026.1 - 1.2 9.1 29.3 1.3 9.0 29.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Protamine_P2 PF00841.19 GBG68026.1 - 1.3 9.6 38.4 3.6 8.1 38.4 1.8 1 1 0 1 1 1 0 Sperm histone P2 GOLD_2 PF13897.6 GBG68026.1 - 1.5 9.3 8.5 1.8 9.0 8.5 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking BUD22 PF09073.10 GBG68026.1 - 2.4 7.4 20.1 3.8 6.7 20.1 1.3 1 0 0 1 1 1 0 BUD22 SpoIIP PF07454.11 GBG68026.1 - 3 7.2 10.4 3.4 7.1 10.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Apt1 PF10351.9 GBG68026.1 - 3.1 6.6 13.3 3.6 6.3 13.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S64 PF08192.11 GBG68026.1 - 4.2 5.7 9.9 4.6 5.6 9.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4360 PF14273.6 GBG68027.1 - 1e-41 142.7 2.1 1.2e-41 142.5 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG68028.1 - 1.5e-40 139.0 2.0 1.9e-40 138.7 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG68029.1 - 8.1e-41 139.8 0.0 9.2e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG68030.1 - 8.6e-23 80.3 0.0 1.5e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68030.1 - 4.1e-18 65.6 0.0 6.9e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68030.1 - 2e-07 30.8 0.1 3e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG68030.1 - 0.57 9.5 10.9 0.75 9.2 10.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG68030.1 - 1.1 7.4 11.5 1.8 6.7 11.5 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG68030.1 - 1.2 7.3 9.6 1.9 6.7 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG68030.1 - 3.6 7.3 6.4 6 6.6 6.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 GBG68030.1 - 5.1 5.1 12.5 6.7 4.7 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Connexin PF00029.19 GBG68031.1 - 0.29 10.9 2.6 0.44 10.3 2.6 1.2 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 GBG68031.1 - 0.52 9.0 1.9 0.71 8.6 1.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 GBG68031.1 - 0.55 9.6 12.3 0.75 9.2 12.3 1.1 1 0 0 1 1 1 0 SDA1 AIF_C PF14721.6 GBG68031.1 - 0.62 10.4 2.4 0.99 9.8 2.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BUD22 PF09073.10 GBG68031.1 - 0.63 9.3 11.7 0.86 8.9 11.7 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG68031.1 - 3.4 6.3 4.4 4.7 5.9 4.4 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG68031.1 - 3.5 5.7 17.4 5 5.2 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG68031.1 - 5.2 6.8 9.3 7.4 6.3 9.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RPN2_C PF18004.1 GBG68031.1 - 5.8 6.8 6.9 9.9 6.1 6.9 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain zf-CCHC PF00098.23 GBG68036.1 - 0.00024 21.0 4.1 0.00061 19.8 4.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG68036.1 - 0.0016 18.2 4.3 0.0016 18.2 4.3 2.2 2 0 0 2 2 2 1 Zinc knuckle Asp-B-Hydro_N PF05279.11 GBG68036.1 - 1.8 8.5 16.1 3 7.9 16.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LMBR1 PF04791.16 GBG68036.1 - 1.9 7.3 3.9 2.3 7.1 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.9 GBG68036.1 - 7.6 5.5 10.2 13 4.7 10.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4360 PF14273.6 GBG68037.1 - 1.6e-36 125.9 0.6 1.9e-36 125.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RVT_1 PF00078.27 GBG68039.1 - 9.4e-08 31.8 0.1 1.3e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop53 PF07767.11 GBG68039.1 - 0.3 10.4 19.3 0.4 10.0 19.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GBG68039.1 - 0.47 8.6 26.1 0.77 7.9 26.1 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG68039.1 - 0.67 9.2 19.6 0.82 8.9 19.6 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG68039.1 - 1.2 7.4 19.4 1.5 7.0 19.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG68039.1 - 2 8.1 22.4 2.8 7.6 22.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LAP1C PF05609.12 GBG68039.1 - 6.3 5.8 12.5 8.5 5.3 12.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4360 PF14273.6 GBG68040.1 - 1.4e-34 119.6 0.0 1.6e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DoxX_2 PF13564.6 GBG68040.1 - 0.083 13.0 0.7 6.2 7.0 0.3 2.2 2 0 0 2 2 2 0 DoxX-like family RT_RNaseH_2 PF17919.1 GBG68041.1 - 1.5e-28 98.7 0.0 2.4e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68041.1 - 2.6e-25 88.7 0.0 4.9e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PTPRCAP PF15713.5 GBG68041.1 - 0.036 14.4 9.0 0.067 13.5 9.0 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 GBG68041.1 - 0.093 12.1 10.7 0.11 11.9 10.7 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG68041.1 - 0.1 10.9 7.9 0.13 10.5 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG68041.1 - 0.24 11.5 10.4 0.33 11.0 10.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GBG68041.1 - 0.53 8.4 10.2 0.59 8.3 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG68041.1 - 6.6 6.0 7.4 9.6 5.4 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein RT_RNaseH_2 PF17919.1 GBG68042.1 - 5.9e-36 122.5 0.0 1.6e-35 121.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68042.1 - 1.2e-32 112.3 0.0 4.2e-32 110.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68042.1 - 5.6e-13 49.1 0.0 1.7e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG68042.1 - 1e-11 44.8 0.1 1.7e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG68042.1 - 1.3e-07 31.6 0.1 2.8e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG68042.1 - 4.8e-05 23.5 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF4360 PF14273.6 GBG68043.1 - 1.5e-36 125.9 0.0 1.7e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DoxX_2 PF13564.6 GBG68043.1 - 0.089 12.9 0.7 14 5.8 0.2 2.3 2 0 0 2 2 2 0 DoxX-like family RT_RNaseH_2 PF17919.1 GBG68044.1 - 2.2e-34 117.4 0.0 4e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68044.1 - 5.2e-31 107.1 0.0 9.2e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68044.1 - 1.5e-05 24.7 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG68045.1 - 0.047 12.0 8.7 0.052 11.8 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 GBG68045.1 - 0.056 13.1 16.4 0.072 12.8 16.4 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop53 PF07767.11 GBG68045.1 - 0.46 9.8 13.2 0.59 9.5 13.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC27 PF09507.10 GBG68045.1 - 1.1 8.6 15.4 1.4 8.3 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 GBG68045.1 - 2.2 6.4 12.7 2.7 6.1 12.7 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 GBG68045.1 - 9.5 5.1 11.4 14 4.6 11.4 1.2 1 0 0 1 1 1 0 Paf1 DUF4360 PF14273.6 GBG68046.1 - 1.5e-77 259.5 3.1 2.9e-40 138.0 1.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4360) Dimer_Tnp_hAT PF05699.14 GBG68047.1 - 0.0016 18.2 0.1 0.0038 17.0 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SH PF01445.17 GBG68047.1 - 9.4 6.3 7.1 4.9 7.2 1.0 2.4 2 0 0 2 2 2 0 Viral small hydrophobic protein zf-FCS PF06467.14 GBG68050.1 - 0.05 13.5 0.5 0.14 12.1 0.5 1.7 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CCHC PF00098.23 GBG68050.1 - 0.59 10.3 3.4 1.3 9.2 3.4 1.5 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 GBG68051.1 - 7.7e-14 51.9 0.0 1.5e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF4942 PF13708.6 GBG68051.1 - 0.034 14.1 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4942) Topo_Zn_Ribbon PF08272.11 GBG68052.1 - 0.054 13.2 0.3 0.054 13.2 0.3 2.0 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like P-mevalo_kinase PF04275.14 GBG68053.1 - 0.096 12.6 0.0 0.86 9.6 0.0 2.2 2 0 0 2 2 2 0 Phosphomevalonate kinase FAM76 PF16046.5 GBG68056.1 - 0.0025 17.2 8.2 0.0043 16.5 8.2 1.3 1 0 0 1 1 1 1 FAM76 protein Retrotrans_gag PF03732.17 GBG68056.1 - 0.0078 16.5 0.1 0.0078 16.5 0.1 3.5 4 0 0 4 4 4 1 Retrotransposon gag protein Bacillus_HBL PF05791.11 GBG68056.1 - 0.7 9.7 6.3 0.054 13.3 1.0 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PspB PF06667.12 GBG68056.1 - 5.2 7.2 13.4 1.8 8.6 0.4 3.2 3 1 0 3 3 3 0 Phage shock protein B APG6_N PF17675.1 GBG68056.1 - 6.6 7.3 26.0 1.4 9.5 1.8 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region ABC_export PF16962.5 GBG68057.1 - 7 5.0 4.3 15 3.9 4.3 1.5 1 0 0 1 1 1 0 Putative ABC exporter Dimer_Tnp_hAT PF05699.14 GBG68059.1 - 0.00027 20.7 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LapA_dom PF06305.11 GBG68064.1 - 0.074 12.9 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Myb_DNA-bind_4 PF13837.6 GBG68065.1 - 7.2e-12 45.5 1.6 7.2e-12 45.5 1.6 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG68065.1 - 0.0023 18.1 0.2 0.0062 16.7 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ApoB100_C PF12491.8 GBG68065.1 - 0.14 12.1 0.0 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal DDE_Tnp_4 PF13359.6 GBG68066.1 - 9.5e-22 77.4 0.0 1.6e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68066.1 - 1.7e-15 57.2 0.0 3.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68066.1 - 0.053 13.2 0.1 1 9.0 0.0 2.7 3 1 0 3 3 3 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG68067.1 - 1.7e-11 44.3 0.5 3.8e-11 43.2 0.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG68067.1 - 0.00026 21.3 1.1 0.0005 20.3 0.4 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG68067.1 - 0.0029 17.7 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG68067.1 - 0.0029 17.7 0.2 0.008 16.4 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG68067.1 - 0.063 13.5 1.3 0.097 12.9 0.1 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF4672 PF15716.5 GBG68068.1 - 4.9 6.7 14.2 7.8 6.1 1.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4672) Lactonase PF10282.9 GBG68069.1 - 0.0016 17.8 0.1 0.029 13.6 0.0 2.3 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 GBG68069.1 - 0.17 11.4 0.0 0.51 9.9 0.0 1.6 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region SGL PF08450.12 GBG68070.1 - 0.12 11.9 0.2 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 GBG68070.1 - 0.13 11.5 0.0 0.36 10.0 0.0 1.6 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Shisa PF13908.6 GBG68070.1 - 0.4 10.9 1.0 0.95 9.7 0.0 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Lactonase PF10282.9 GBG68071.1 - 0.013 14.7 0.0 0.044 13.0 0.0 1.7 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller SGL PF08450.12 GBG68071.1 - 0.14 11.8 0.2 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Shisa PF13908.6 GBG68071.1 - 0.39 11.0 0.0 0.39 11.0 0.0 2.6 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Lactonase PF10282.9 GBG68072.1 - 0.00095 18.5 0.0 0.0028 16.9 0.0 1.8 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 GBG68072.1 - 1.4 9.5 4.4 2.2 8.9 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain SGL PF08450.12 GBG68073.1 - 0.041 13.5 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 GBG68073.1 - 0.13 11.5 0.0 0.44 9.8 0.0 1.5 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Sortilin-Vps10 PF15902.5 GBG68073.1 - 0.2 10.4 0.1 4.2 6.0 0.0 2.1 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, SGL PF08450.12 GBG68074.1 - 0.00084 19.0 0.0 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 GBG68074.1 - 0.016 14.5 0.0 0.084 12.1 0.0 1.9 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller TMEM51 PF15345.6 GBG68074.1 - 0.039 13.8 1.2 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 LapA_dom PF06305.11 GBG68074.1 - 0.18 11.6 0.2 0.42 10.5 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AJAP1_PANP_C PF15298.6 GBG68074.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DDE_Tnp_4 PF13359.6 GBG68075.1 - 8.4e-30 103.5 0.0 1.4e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68075.1 - 7.7e-14 51.8 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68075.1 - 0.015 15.0 0.1 3.8 7.1 0.1 2.3 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG68076.1 - 8.3e-06 26.1 3.0 8.6e-06 26.1 0.2 2.4 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG68076.1 - 0.098 13.0 0.3 0.33 11.3 0.3 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SGL PF08450.12 GBG68077.1 - 0.0068 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 GBG68077.1 - 0.0075 15.6 0.1 0.03 13.6 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Myc_target_1 PF15179.6 GBG68077.1 - 0.014 15.3 0.7 0.044 13.7 0.0 2.2 2 0 0 2 2 2 0 Myc target protein 1 YL1 PF05764.13 GBG68081.1 - 0.0069 16.5 23.0 0.0095 16.1 23.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 GBG68081.1 - 0.049 11.9 20.8 0.057 11.6 20.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG68081.1 - 0.62 9.4 23.4 0.77 9.1 23.4 1.2 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 GBG68081.1 - 1.4 7.9 11.5 1.6 7.7 11.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Lin-8 PF03353.15 GBG68081.1 - 6.4 6.2 16.9 9 5.8 16.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist gag-asp_proteas PF13975.6 GBG68082.1 - 5.5e-07 30.1 0.0 1.7e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG68082.1 - 0.0017 18.6 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68082.1 - 0.0034 18.0 0.1 0.012 16.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG68082.1 - 0.0059 16.8 4.1 0.0059 16.8 4.1 3.3 4 0 0 4 4 4 1 JNK_SAPK-associated protein-1 Asp_protease PF09668.10 GBG68082.1 - 0.0088 15.8 1.1 0.018 14.8 1.1 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF3347 PF11827.8 GBG68082.1 - 0.23 11.6 0.8 0.62 10.2 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Pkinase_Tyr PF07714.17 GBG68083.1 - 1.2e-20 73.9 0.0 3.3e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG68083.1 - 2.1e-17 63.4 0.0 8.8e-17 61.3 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 GBG68083.1 - 2.3e-10 40.9 0.3 0.17 12.8 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat EDS1_EP PF18117.1 GBG68083.1 - 0.012 16.1 1.1 0.063 13.7 1.4 2.0 2 0 0 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain Nup160 PF11715.8 GBG68083.1 - 0.012 14.2 0.2 2.6 6.6 0.0 2.8 2 1 0 3 3 3 0 Nucleoporin Nup120/160 DUF572 PF04502.13 GBG68083.1 - 0.16 11.5 6.1 0.24 11.0 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4600 PF15372.6 GBG68083.1 - 5.4 7.5 13.2 0.96 9.9 8.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Exonuc_VII_L PF02601.15 GBG68083.1 - 9.7 5.7 7.1 15 5.1 7.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 GBG68084.1 - 9.9e-19 67.7 0.0 1.1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG68084.1 - 3.5e-18 65.8 0.0 4.8e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Integrase_H2C2 PF17921.1 GBG68085.1 - 1.7e-19 69.7 0.2 3.3e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG68085.1 - 3e-19 69.2 0.2 7.2e-19 68.0 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68085.1 - 2.4e-15 56.7 0.0 9.1e-15 54.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG68085.1 - 2.8e-11 43.3 0.0 8e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG68085.1 - 2.2e-06 28.1 0.0 2.2e-06 28.1 0.0 3.6 4 1 0 4 4 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68085.1 - 0.00041 20.9 0.0 0.00041 20.9 0.0 3.6 3 1 0 3 3 3 1 Aspartyl protease zf-H2C2 PF09337.10 GBG68085.1 - 0.00041 20.5 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG68085.1 - 0.011 15.5 0.4 0.041 13.6 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) DUF1758 PF05585.12 GBG68085.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG68085.1 - 0.031 14.1 0.0 0.088 12.6 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease BAF250_C PF12031.8 GBG68085.1 - 0.031 13.6 0.2 0.074 12.3 0.2 1.6 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa RT_RNaseH_2 PF17919.1 GBG68086.1 - 4.6e-34 116.4 0.0 1.3e-33 115.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68086.1 - 6.2e-31 106.8 0.3 4e-30 104.2 0.1 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68086.1 - 4.9e-19 68.2 0.1 9.7e-19 67.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68086.1 - 6.2e-12 45.8 0.1 4e-11 43.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG68086.1 - 0.0071 16.2 0.1 0.42 10.5 0.0 2.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG68086.1 - 0.073 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG68087.1 - 2.8e-15 56.4 0.3 9.4e-15 54.6 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68087.1 - 1.3e-09 37.9 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68087.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain Pkinase PF00069.25 GBG68088.1 - 7.7e-18 64.8 0.0 1e-15 57.8 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG68088.1 - 2.5e-17 63.0 0.0 2.2e-09 37.0 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Myosin_tail_1 PF01576.19 GBG68088.1 - 0.0014 16.6 15.4 0.002 16.1 15.4 1.2 1 0 0 1 1 1 1 Myosin tail Dak1_2 PF13684.6 GBG68088.1 - 0.0076 15.4 0.4 0.012 14.8 0.4 1.3 1 0 0 1 1 1 1 Dihydroxyacetone kinase family CCDC158 PF15921.5 GBG68088.1 - 0.091 10.6 13.2 0.12 10.1 13.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 GAS PF13851.6 GBG68088.1 - 0.13 11.6 19.7 0.2 11.0 19.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding NUDE_C PF04880.13 GBG68088.1 - 0.21 12.1 11.1 0.18 12.3 9.5 1.7 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region DP PF08781.10 GBG68088.1 - 0.21 11.5 6.1 0.62 10.0 3.4 2.4 2 0 0 2 2 2 0 Transcription factor DP Atg14 PF10186.9 GBG68088.1 - 0.96 8.5 12.6 1.4 8.0 12.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DASH_Dam1 PF08653.10 GBG68088.1 - 1 9.2 3.1 13 5.7 0.1 3.2 2 1 0 2 2 2 0 DASH complex subunit Dam1 WD40_alt PF14077.6 GBG68088.1 - 1.4 8.8 4.0 9.1 6.2 0.1 3.3 2 1 1 3 3 3 0 Alternative WD40 repeat motif DUF1664 PF07889.12 GBG68088.1 - 1.5 8.9 10.3 4.3 7.4 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 GBG68088.1 - 2.6 8.2 13.7 8.3 6.6 4.8 3.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 GBG68088.1 - 2.8 8.5 21.6 2.6 8.6 15.7 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 GBG68088.1 - 3.1 7.9 21.6 3.4 7.7 2.2 3.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FAM76 PF16046.5 GBG68088.1 - 4.3 6.6 14.2 6.6 6.0 14.2 1.2 1 0 0 1 1 1 0 FAM76 protein UPF0242 PF06785.11 GBG68088.1 - 4.6 7.3 14.4 7.4 6.6 14.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 GBG68088.1 - 5.1 7.1 22.2 9.2 6.3 22.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.12 GBG68088.1 - 7.1 7.2 15.3 2.7 8.6 11.9 2.1 1 1 1 2 2 2 0 Striatin family Syntaxin-6_N PF09177.11 GBG68088.1 - 8.4 7.0 9.0 3.1 8.4 6.0 1.9 2 1 0 2 2 1 0 Syntaxin 6, N-terminal RVT_1 PF00078.27 GBG68090.1 - 8e-28 97.5 0.0 1.2e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68090.1 - 3.5e-11 43.0 0.0 1e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG68090.1 - 0.0062 17.1 0.0 0.018 15.6 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Pkinase PF00069.25 GBG68092.1 - 1.1e-21 77.4 0.2 2.3e-21 76.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG68092.1 - 3.3e-19 69.2 0.0 5.8e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FPP PF05911.11 GBG68092.1 - 0.075 11.2 17.0 0.1 10.8 17.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF3552 PF12072.8 GBG68092.1 - 1.3 8.4 23.4 2.1 7.7 23.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) UPF0242 PF06785.11 GBG68092.1 - 5.6 7.0 17.7 8.7 6.4 17.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ribosomal_S4 PF00163.19 GBG68093.1 - 1.8e-06 28.7 2.3 7.6e-06 26.8 2.2 2.0 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Myb_DNA-bind_4 PF13837.6 GBG68094.1 - 3.8e-07 30.4 0.8 8.7e-07 29.2 0.8 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 GBG68095.1 - 6.5e-24 84.7 0.0 2.4e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG68095.1 - 7.1e-20 71.4 0.0 1.4e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG68095.1 - 2.5e-07 31.3 3.6 7.9e-05 23.4 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CLZ PF16526.5 GBG68095.1 - 0.013 15.8 17.7 0.15 12.4 4.7 2.9 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lectin_N PF03954.14 GBG68095.1 - 0.078 12.7 3.8 0.2 11.4 3.8 1.8 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 GBG68095.1 - 1.8 9.1 3.7 5.4 7.5 1.9 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-CCHC PF00098.23 GBG68096.1 - 0.00037 20.4 4.2 0.001 19.1 4.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG68096.1 - 0.032 13.9 2.7 0.076 12.7 2.7 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Ribosomal_S3_C PF00189.20 GBG68096.1 - 0.065 13.8 0.4 0.21 12.1 0.4 1.8 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain Dimer_Tnp_hAT PF05699.14 GBG68097.1 - 2.1e-05 24.2 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SURF2 PF05477.11 GBG68100.1 - 0.018 14.8 0.8 0.21 11.2 0.6 2.4 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Podoplanin PF05808.11 GBG68102.1 - 0.036 14.2 0.5 0.069 13.3 0.3 1.5 1 1 0 1 1 1 0 Podoplanin RVT_1 PF00078.27 GBG68103.1 - 2e-34 119.0 0.1 3.3e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68103.1 - 2.6e-29 101.6 0.0 6.7e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68103.1 - 1.7e-22 79.3 0.0 4.9e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68103.1 - 5.4e-14 52.0 0.1 1.2e-13 50.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Nop14 PF04147.12 GBG68103.1 - 0.00022 19.6 34.4 0.00022 19.6 34.4 2.3 2 0 0 2 2 2 1 Nop14-like family SDA1 PF05285.12 GBG68103.1 - 0.0026 17.3 41.2 0.0026 17.3 41.2 2.7 2 1 0 2 2 2 1 SDA1 zf-H2C2 PF09337.10 GBG68103.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG68104.1 - 2.8e-29 101.1 0.0 5.4e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68104.1 - 8.5e-29 99.9 0.0 1.6e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68104.1 - 1.8e-08 34.1 0.1 3.4e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG68104.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FAM60A PF15396.6 GBG68105.1 - 0.094 12.7 5.9 0.12 12.4 5.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF5401 PF17380.2 GBG68105.1 - 0.26 9.3 28.7 0.3 9.1 28.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4604 PF15377.6 GBG68105.1 - 0.74 10.2 17.0 0.91 9.9 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) TadF PF16964.5 GBG68105.1 - 0.81 9.4 3.1 1 9.1 3.1 1.1 1 0 0 1 1 1 0 Putative tight adherence pilin protein F RR_TM4-6 PF06459.12 GBG68105.1 - 2.5 7.8 17.4 3.3 7.5 17.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 GBG68105.1 - 2.6 8.3 15.9 3.5 7.9 15.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 GBG68105.1 - 2.8 6.0 28.6 4.5 5.4 28.6 1.4 1 1 0 1 1 1 0 Nop14-like family LicD PF04991.13 GBG68105.1 - 4.3 7.4 7.1 5.7 7.0 7.1 1.1 1 0 0 1 1 1 0 LicD family PIEZO PF15917.5 GBG68105.1 - 4.8 6.6 15.9 6.1 6.3 15.9 1.1 1 0 0 1 1 1 0 Piezo DBINO PF13892.6 GBG68105.1 - 5.3 7.4 22.4 10 6.5 22.4 1.4 1 0 0 1 1 1 0 DNA-binding domain DUF4407 PF14362.6 GBG68105.1 - 5.6 6.2 7.4 7.3 5.9 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PA26 PF04636.13 GBG68105.1 - 7 5.5 8.1 8.2 5.2 8.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Spore_coat_CotO PF14153.6 GBG68105.1 - 7.1 6.5 20.3 8.8 6.2 20.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Rtf2 PF04641.12 GBG68105.1 - 9.1 5.6 17.8 12 5.1 17.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger AAA_11 PF13086.6 GBG68105.1 - 9.2 6.0 10.9 11 5.7 10.9 1.1 1 0 0 1 1 1 0 AAA domain RT_RNaseH PF17917.1 GBG68106.1 - 7.9e-25 87.2 0.6 4.1e-24 84.9 0.2 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68106.1 - 5.5e-18 64.8 0.3 3.2e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68106.1 - 1.6e-15 57.3 0.2 5.7e-15 55.6 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG68106.1 - 1.1e-14 54.3 0.0 3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG68106.1 - 0.018 15.2 0.0 0.075 13.3 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger DUF2862 PF11061.8 GBG68106.1 - 0.11 12.4 0.1 0.41 10.5 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) RVT_1 PF00078.27 GBG68108.1 - 2e-33 115.8 0.0 3.6e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68108.1 - 2.6e-30 104.4 0.0 6.2e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68108.1 - 1.2e-25 89.9 0.0 2.5e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2408 PF10303.9 GBG68108.1 - 0.042 14.4 0.2 0.12 12.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Rhamno_transf PF11316.8 GBG68108.1 - 0.048 13.0 0.6 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative rhamnosyl transferase Phage_GPO PF05929.11 GBG68108.1 - 5 6.7 7.2 22 4.5 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG68109.1 - 9e-61 202.1 0.1 1.2e-32 111.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68109.1 - 1.8e-60 201.7 0.3 3.6e-29 101.1 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68109.1 - 4.1e-33 113.3 2.4 1.1e-16 60.7 0.1 2.9 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG68109.1 - 4.3e-32 111.4 0.1 1.4e-31 109.7 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2584 PF10763.9 GBG68109.1 - 0.038 14.2 0.1 20 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2584) zf-H2C2 PF09337.10 GBG68109.1 - 0.046 13.9 0.1 9.7 6.5 0.0 3.1 2 0 0 2 2 2 0 H2C2 zinc finger NAAA-beta PF15508.6 GBG68109.1 - 0.071 13.4 0.2 1.2 9.5 0.0 3.1 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1266 PF06889.11 GBG68109.1 - 0.11 12.6 0.1 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DUF5095 PF17016.5 GBG68109.1 - 0.61 9.7 2.1 0.42 10.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) IceA2 PF05862.11 GBG68109.1 - 0.64 10.0 1.9 8.8 6.3 0.1 2.5 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein RT_RNaseH_2 PF17919.1 GBG68110.1 - 8.3e-34 115.6 0.1 1.7e-33 114.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68110.1 - 4.1e-30 104.2 0.2 1.4e-29 102.4 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68110.1 - 3.6e-06 26.7 0.1 7e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Apc13p PF05839.11 GBG68110.1 - 0.0016 18.6 2.9 0.0052 17.0 1.7 2.5 2 0 0 2 2 2 1 Apc13p protein She9_MDM33 PF05546.11 GBG68110.1 - 0.1 12.4 2.5 0.38 10.5 0.0 2.5 2 0 0 2 2 2 0 She9 / Mdm33 family rve_3 PF13683.6 GBG68111.1 - 0.0048 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 GBG68111.1 - 0.0086 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG68112.1 - 7e-33 112.6 0.1 1.4e-32 111.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68112.1 - 8.1e-33 113.8 0.1 1.5e-32 112.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68112.1 - 1e-28 99.7 0.2 2.2e-28 98.6 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68112.1 - 9e-19 67.3 0.1 2.8e-18 65.7 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68112.1 - 1.9e-12 47.4 0.1 4.4e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG68112.1 - 0.024 14.8 0.3 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG68113.1 - 0.056 13.5 0.2 0.18 11.9 0.2 2.0 1 0 0 1 1 1 0 Zinc knuckle DUF4416 PF14385.6 GBG68113.1 - 0.061 13.2 3.3 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4416) RT_RNaseH_2 PF17919.1 GBG68114.1 - 8.1e-19 67.5 0.0 2.1e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68114.1 - 1.1e-13 51.4 0.0 2.7e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG68114.1 - 2.4e-11 43.6 0.0 4.4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68114.1 - 5.6e-08 33.0 0.0 1.7e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG68114.1 - 0.0074 16.5 0.1 0.039 14.2 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG68114.1 - 0.032 14.2 0.9 0.062 13.3 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle HepII_C PF18675.1 GBG68114.1 - 0.055 13.6 0.0 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Heparinase II C-terminal domain Integrase_H2C2 PF17921.1 GBG68115.1 - 1.2e-13 51.0 0.0 2.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG68115.1 - 1.7e-12 47.5 0.3 3.5e-12 46.5 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68115.1 - 9.6e-10 38.7 0.0 2.9e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG68115.1 - 0.0021 18.0 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG68115.1 - 0.017 14.9 0.0 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease Pes-10 PF07149.11 GBG68117.1 - 0.17 10.9 8.6 0.29 10.2 8.6 1.3 1 0 0 1 1 1 0 Pes-10 LicD PF04991.13 GBG68117.1 - 0.42 10.7 8.7 0.17 12.0 4.7 2.1 2 0 0 2 2 2 0 LicD family Nop14 PF04147.12 GBG68117.1 - 0.78 7.9 20.8 1.5 7.0 20.8 1.4 1 0 0 1 1 1 0 Nop14-like family N6_N4_Mtase PF01555.18 GBG68118.1 - 2.2e-06 27.5 0.0 4.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 DNA methylase Rtt106_N PF18215.1 GBG68118.1 - 0.16 11.7 0.0 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain Glyco_hydro_53 PF07745.13 GBG68119.1 - 0.085 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Dimer_Tnp_hAT PF05699.14 GBG68120.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG68122.1 - 2.2e-33 114.2 0.0 5.5e-33 113.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68122.1 - 4.6e-30 104.0 0.0 1e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68122.1 - 1.1e-28 100.3 0.1 1.7e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG68122.1 - 1.1e-18 67.6 0.1 8.2e-12 45.4 0.0 3.1 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG68122.1 - 1.3e-07 31.6 1.2 1e-06 28.7 0.0 2.9 2 0 0 2 2 2 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG68122.1 - 1.5e-07 31.1 0.8 4.9e-07 29.5 0.8 2.0 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG68122.1 - 8.8e-06 25.5 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG68122.1 - 0.00019 21.9 0.0 0.0005 20.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG68122.1 - 0.0002 21.5 0.0 0.0002 21.5 0.0 2.2 2 0 0 2 2 1 1 H2C2 zinc finger zf-CCHC_2 PF13696.6 GBG68122.1 - 0.002 17.9 3.3 0.002 17.9 3.3 2.8 3 0 0 3 3 3 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG68122.1 - 0.017 15.7 0.0 0.047 14.3 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Chromo PF00385.24 GBG68122.1 - 0.18 11.8 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG68123.1 - 2.6e-31 108.9 0.0 4.2e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG68123.1 - 9.4e-13 48.1 0.1 2.4e-12 46.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68123.1 - 7.5e-12 45.5 0.2 7.8e-11 42.2 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG68123.1 - 6.6e-05 23.0 0.1 0.00016 21.8 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG68124.1 - 4.7e-53 177.4 0.0 2e-29 101.6 0.0 3.1 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68124.1 - 3.4e-50 170.6 0.8 4e-34 118.1 0.1 3.6 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68124.1 - 2.1e-41 140.5 0.1 1.3e-28 99.3 0.0 3.1 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG68127.1 - 4.8e-05 23.6 5.3 0.00025 21.2 0.0 3.6 3 1 0 3 3 3 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG68127.1 - 0.002 18.7 2.1 0.002 18.7 2.1 2.9 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 GBG68127.1 - 0.01 16.3 0.6 0.18 12.3 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SPARC_Ca_bdg PF10591.9 GBG68127.1 - 0.37 11.1 2.7 0.3 11.4 0.4 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region BLOC1_2 PF10046.9 GBG68127.1 - 0.47 10.8 3.8 2.7 8.4 0.6 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 GBG68127.1 - 1.2 8.4 15.3 3 7.1 7.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 GBG68127.1 - 9.4 6.3 15.8 0.27 11.3 0.9 3.7 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding RT_RNaseH_2 PF17919.1 GBG68128.1 - 8.5e-33 112.4 0.1 2.8e-32 110.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68128.1 - 3.5e-27 94.8 0.0 9.4e-27 93.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68128.1 - 5.4e-16 58.4 0.1 1.1e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG68128.1 - 2.9e-13 49.9 0.0 6.4e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG68128.1 - 2.6e-06 27.3 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68128.1 - 0.0023 18.6 0.0 0.0063 17.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG68128.1 - 0.005 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG68128.1 - 0.019 15.5 0.0 0.053 14.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CENP-Q PF13094.6 GBG68128.1 - 0.023 14.9 1.1 0.023 14.9 1.1 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-CCHC PF00098.23 GBG68129.1 - 4.1e-05 23.5 2.7 0.00012 22.0 2.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG68129.1 - 0.031 14.0 2.5 0.068 12.9 2.5 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger EBV-NA3 PF05009.12 GBG68129.1 - 0.042 13.4 0.2 0.074 12.6 0.2 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RVT_1 PF00078.27 GBG68130.1 - 2.9e-27 95.7 0.1 5.7e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68130.1 - 3.5e-10 39.8 0.0 1.2e-09 38.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG68130.1 - 1.8e-06 28.4 0.0 0.023 15.2 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68130.1 - 3.3e-06 27.7 0.0 0.01 16.5 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.10 GBG68130.1 - 0.00013 21.8 0.0 0.055 13.3 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG68130.1 - 0.00023 20.9 0.0 0.0074 16.1 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG68130.1 - 0.0051 17.1 0.1 0.0051 17.1 0.1 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG68130.1 - 0.033 14.5 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG68131.1 - 2.6e-09 36.8 0.0 1.4e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG68131.1 - 0.0001 22.5 3.3 0.47 10.7 0.1 3.7 3 2 1 4 4 4 2 Retrotransposon gag protein Binary_toxB_3 PF17476.2 GBG68131.1 - 0.014 15.5 1.1 6.7 6.9 0.1 2.7 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA domain 3 rve PF00665.26 GBG68131.1 - 0.047 13.9 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF1664 PF07889.12 GBG68131.1 - 0.049 13.7 6.6 2.3 8.3 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) FliMN_C PF01052.20 GBG68131.1 - 0.099 12.7 2.5 12 5.9 0.1 2.6 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term Rad60-SLD PF11976.8 GBG68131.1 - 0.16 11.8 0.0 8.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like RNA_polI_A34 PF08208.11 GBG68132.1 - 0.002 18.2 34.9 0.025 14.7 34.8 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 CPSF100_C PF13299.6 GBG68132.1 - 0.97 9.6 16.2 2 8.6 16.2 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 GBG68132.1 - 1.3 9.1 6.6 1.6 8.8 6.6 1.3 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 GBG68132.1 - 2.3 7.9 11.7 3.1 7.5 11.7 1.3 1 0 0 1 1 1 0 AAA domain DUF913 PF06025.12 GBG68132.1 - 5.5 5.9 8.6 7.2 5.5 8.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 GBG68132.1 - 7.6 4.6 26.1 10 4.2 26.1 1.2 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG68133.1 - 1.4e-23 83.6 0.1 2.3e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG68133.1 - 5.4e-05 23.1 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG68133.1 - 0.0054 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Cwf_Cwc_15 PF04889.12 GBG68133.1 - 0.055 13.2 0.5 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 GBG68133.1 - 0.071 13.2 0.7 0.15 12.1 0.7 1.5 1 0 0 1 1 1 0 YL1 nuclear protein DUF4311 PF14188.6 GBG68133.1 - 0.24 11.1 0.1 0.41 10.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) Myb_DNA-bind_4 PF13837.6 GBG68134.1 - 5.8e-08 33.0 2.4 2e-07 31.3 2.4 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG68134.1 - 0.0023 18.2 2.8 0.0059 16.9 2.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG68134.1 - 0.53 10.4 2.4 1.1 9.4 2.4 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain FAM27 PF15832.5 GBG68135.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 FAM27 D and E protein family Swi6_N PF18530.1 GBG68135.1 - 0.21 11.7 0.8 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 Swi6 N-terminal domain BUD22 PF09073.10 GBG68135.1 - 1.3 8.2 12.6 2.9 7.2 12.6 1.5 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG68135.1 - 9.4 4.3 14.0 13 3.8 14.0 1.1 1 0 0 1 1 1 0 Nop14-like family gag-asp_proteas PF13975.6 GBG68136.1 - 8.3e-07 29.5 0.0 2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68136.1 - 0.00011 22.7 0.0 0.00029 21.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68136.1 - 0.00026 20.8 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68136.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease ATE_N PF04376.13 GBG68136.1 - 0.052 13.9 0.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus Peptidase_C48 PF02902.19 GBG68138.1 - 3.2e-23 82.7 0.1 8.4e-23 81.3 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain ChuX_HutX PF06228.13 GBG68138.1 - 0.16 11.8 0.1 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX RVT_1 PF00078.27 GBG68139.1 - 0.0027 17.3 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRTP PF01366.18 GBG68140.1 - 0.067 11.2 5.4 0.071 11.2 5.4 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF1949 PF09186.11 GBG68140.1 - 0.09 12.7 0.2 0.32 10.9 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) TerB_C PF15615.6 GBG68140.1 - 0.14 12.5 14.0 0.19 12.0 14.0 1.2 1 0 0 1 1 1 0 TerB-C domain DUF5401 PF17380.2 GBG68140.1 - 0.15 10.1 15.8 0.15 10.1 15.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF2347 PF09804.9 GBG68140.1 - 0.57 9.7 3.2 0.7 9.4 3.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) STAT_bind PF02864.15 GBG68140.1 - 1.5 9.4 5.0 3.2 8.3 5.0 1.5 1 1 0 1 1 1 0 STAT protein, DNA binding domain PPL5 PF18168.1 GBG68140.1 - 1.5 8.0 5.9 1.7 7.9 5.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S49_N PF08496.10 GBG68140.1 - 1.8 8.6 9.1 2.3 8.3 9.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rtf2 PF04641.12 GBG68140.1 - 2.4 7.5 12.8 2.6 7.3 12.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Vfa1 PF08432.10 GBG68140.1 - 3.6 7.9 14.7 4.3 7.6 14.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF5093 PF17011.5 GBG68140.1 - 4 7.7 8.2 3.4 8.0 7.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5093) DUF2052 PF09747.9 GBG68140.1 - 4.8 7.3 16.5 6 6.9 16.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TP53IP5 PF15331.6 GBG68140.1 - 5.9 7.0 10.3 6.5 6.8 10.3 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PA26 PF04636.13 GBG68140.1 - 6.3 5.6 8.4 6.6 5.5 8.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Paf1 PF03985.13 GBG68140.1 - 7.5 5.4 16.9 8.8 5.2 16.9 1.2 1 0 0 1 1 1 0 Paf1 TFB6 PF17110.5 GBG68140.1 - 9.3 6.0 8.5 12 5.6 8.2 1.4 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RT_RNaseH PF17917.1 GBG68141.1 - 8.3e-26 90.3 0.0 2.5e-25 88.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68141.1 - 2e-25 88.7 0.0 4.4e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68141.1 - 1.4e-19 69.9 0.4 3.1e-19 68.8 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG68141.1 - 4.6e-07 30.0 0.0 2.6e-06 27.6 0.0 2.4 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG68141.1 - 0.0035 17.2 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-H2C2 PF09337.10 GBG68141.1 - 0.0059 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG68141.1 - 0.068 13.4 1.4 0.19 12.0 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein JIP_LZII PF16471.5 GBG68141.1 - 0.14 12.3 0.4 0.6 10.3 0.4 2.1 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF4187 PF13821.6 GBG68141.1 - 0.63 9.9 9.6 0.035 13.9 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Methyltransf_21 PF05050.12 GBG68142.1 - 2.4e-08 34.2 0.0 3.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_21 PF05050.12 GBG68143.1 - 0.00022 21.3 0.0 0.00026 21.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain RT_RNaseH PF17917.1 GBG68144.1 - 3.1e-24 85.3 0.0 1.2e-23 83.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68144.1 - 1.5e-22 79.5 0.3 9.3e-22 77.0 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68144.1 - 5.2e-21 75.2 0.4 2.2e-20 73.2 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG68144.1 - 9.6e-20 70.5 0.1 1.9e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG68144.1 - 5e-06 26.3 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68144.1 - 3.3e-05 24.4 0.0 0.00011 22.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68144.1 - 0.00027 21.4 0.0 0.0012 19.4 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG68144.1 - 0.0045 17.2 0.0 0.02 15.1 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG68144.1 - 0.044 14.0 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger WTX PF09422.10 GBG68144.1 - 0.047 12.8 2.4 0.082 12.0 2.4 1.3 1 0 0 1 1 1 0 WTX protein Integrase_H2C2 PF17921.1 GBG68146.1 - 2.9e-15 56.1 0.7 8.7e-15 54.6 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG68146.1 - 3.4e-07 30.7 0.0 1.1e-06 29.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG68146.1 - 2e-06 28.0 0.0 4.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG68146.1 - 7.4e-06 26.5 0.3 4.9e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG68146.1 - 0.00082 19.4 0.0 0.0026 17.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG68146.1 - 0.0014 18.4 0.6 0.0025 17.6 0.6 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG68146.1 - 0.0044 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG68147.1 - 9.2e-14 51.3 0.1 2e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68147.1 - 7.8e-06 26.1 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG68147.1 - 0.0094 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68147.1 - 0.041 14.5 0.0 0.086 13.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease N6_N4_Mtase PF01555.18 GBG68148.1 - 3.2e-07 30.3 0.0 3.2e-07 30.3 0.0 2.3 2 1 0 2 2 2 1 DNA methylase Nop14 PF04147.12 GBG68148.1 - 0.0002 19.7 42.2 0.00051 18.4 42.2 1.6 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG68148.1 - 0.00041 19.9 45.0 0.0012 18.3 45.0 1.7 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG68148.1 - 0.0029 16.0 29.6 0.0057 15.0 29.6 1.4 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 GBG68148.1 - 0.0071 15.2 17.8 0.012 14.4 17.8 1.3 1 0 0 1 1 1 1 Presenilin Raftlin PF15250.6 GBG68148.1 - 0.051 12.3 11.7 0.12 11.1 11.7 1.6 1 0 0 1 1 1 0 Raftlin AAA_11 PF13086.6 GBG68148.1 - 0.26 11.0 16.6 0.55 10.0 16.6 1.5 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 GBG68148.1 - 1.6 7.7 14.0 2.6 7.0 14.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 GBG68148.1 - 4.8 7.1 8.3 15 5.5 8.3 1.9 1 0 0 1 1 1 0 Protein Family FAM60A Mpp10 PF04006.12 GBG68148.1 - 5.6 5.3 57.9 2.2 6.6 55.3 1.6 2 0 0 2 2 2 0 Mpp10 protein RVT_1 PF00078.27 GBG68149.1 - 8.1e-24 84.4 0.0 1.5e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68149.1 - 2.5e-22 78.8 0.0 3.4e-16 59.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68149.1 - 3.3e-15 55.9 0.0 3.3e-15 55.9 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG68149.1 - 2.3e-14 53.6 0.0 7.2e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG68149.1 - 2.9e-11 43.1 0.0 5.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG68149.1 - 1.7e-10 41.1 0.0 4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG68149.1 - 0.00049 20.3 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG68150.1 - 1.9e-25 88.8 0.0 7.6e-25 86.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68150.1 - 1.6e-23 83.0 0.0 5.2e-23 81.3 0.0 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68150.1 - 4.1e-20 72.3 0.0 7.9e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG68150.1 - 8.8e-17 61.0 0.1 3.8e-16 59.0 0.1 2.2 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68150.1 - 2.4e-09 37.4 0.0 7.8e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG68150.1 - 3.3e-07 30.8 0.0 2e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68150.1 - 6.9e-07 29.8 0.0 2.4e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG68150.1 - 3.6e-06 26.8 0.0 8.9e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG68150.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG68150.1 - 0.013 15.8 1.8 0.044 14.1 0.2 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein Chromo PF00385.24 GBG68150.1 - 0.028 14.3 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF4360 PF14273.6 GBG68151.1 - 1.3e-39 135.9 1.1 1.5e-39 135.7 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG68152.1 - 2.9e-31 107.5 0.0 3.3e-16 59.1 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68152.1 - 8.8e-30 103.9 0.0 1.4e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68152.1 - 8.2e-29 100.0 0.0 3.5e-28 97.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68152.1 - 8.9e-16 57.8 0.0 8.9e-16 57.8 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG68152.1 - 2.8e-10 40.4 0.0 1.1e-09 38.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG68152.1 - 2.4e-05 24.4 0.0 6.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG68153.1 - 0.0015 18.0 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG68153.1 - 0.62 9.3 37.1 0.96 8.7 37.1 1.4 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 GBG68153.1 - 0.71 8.9 28.5 0.97 8.4 28.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RVT_1 PF00078.27 GBG68154.1 - 5.5e-34 117.6 0.0 7.4e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM110_C PF14160.6 GBG68155.1 - 0.044 14.9 1.9 23 6.1 0.0 2.8 2 0 0 2 2 2 0 Centrosome-associated C terminus TP53IP5 PF15331.6 GBG68155.1 - 0.83 9.8 4.3 1.4 9.0 4.3 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 TrkA_C PF02080.21 GBG68157.1 - 0.0033 17.2 0.0 3.5 7.5 0.0 2.4 2 0 0 2 2 2 2 TrkA-C domain DUF4360 PF14273.6 GBG68158.1 - 1.1e-47 162.2 0.2 1.3e-47 162.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF659 PF04937.15 GBG68159.1 - 1.5e-27 96.4 0.0 2.5e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG68159.1 - 3e-08 33.3 0.0 6.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG68160.1 - 6.7e-68 225.0 0.6 8.7e-33 112.3 0.1 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68160.1 - 1.4e-54 182.8 0.1 1.2e-29 102.7 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68160.1 - 1.4e-08 34.5 0.1 6.2e-08 32.4 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG68160.1 - 7.1e-05 22.8 0.1 0.00019 21.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG68160.1 - 0.0012 19.0 0.1 0.0031 17.7 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RGS-like PF09128.11 GBG68161.1 - 0.57 9.9 9.5 1.2 8.8 9.5 1.5 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain BT1 PF03092.16 GBG68161.1 - 9.5 4.3 6.7 14 3.8 6.7 1.1 1 0 0 1 1 1 0 BT1 family Med2 PF11214.8 GBG68162.1 - 0.006 16.7 3.6 0.011 15.8 3.6 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 RNase_P_Rpp14 PF01900.19 GBG68163.1 - 0.2 11.9 0.0 0.55 10.5 0.0 1.7 1 0 0 1 1 1 0 Rpp14/Pop5 family DDE_Tnp_4 PF13359.6 GBG68164.1 - 5.5e-06 26.1 0.0 7.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Barwin PF00967.17 GBG68164.1 - 0.028 14.3 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Barwin family SDA1 PF05285.12 GBG68165.1 - 5.2e-09 36.0 27.1 9e-09 35.2 27.1 1.3 1 0 0 1 1 1 1 SDA1 SAPS PF04499.15 GBG68165.1 - 0.0024 16.7 8.7 0.0031 16.4 8.7 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein NPR3 PF03666.13 GBG68165.1 - 0.0047 15.8 11.5 0.0077 15.1 11.5 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 GBG68165.1 - 0.015 13.5 44.7 0.022 13.0 44.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG68165.1 - 1.4 7.1 43.7 2.1 6.5 43.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GBG68165.1 - 1.9 6.8 46.9 2.9 6.2 46.9 1.2 1 0 0 1 1 1 0 Mpp10 protein Drc1-Sld2 PF11719.8 GBG68165.1 - 2.4 7.6 28.2 4.6 6.7 28.2 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein Presenilin PF01080.17 GBG68165.1 - 2.6 6.7 18.7 3.7 6.2 18.7 1.1 1 0 0 1 1 1 0 Presenilin DUF4360 PF14273.6 GBG68166.1 - 8.2e-38 130.0 1.6 9.5e-38 129.8 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF3551 PF12071.8 GBG68166.1 - 0.38 10.8 2.4 0.68 10.0 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) RT_RNaseH_2 PF17919.1 GBG68167.1 - 3.7e-11 43.0 0.1 1.1e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68167.1 - 5e-05 22.9 0.0 8.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Autophagy_N PF03986.13 GBG68167.1 - 0.046 13.7 1.9 0.09 12.7 1.9 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Na_trans_assoc PF06512.13 GBG68167.1 - 1.4 9.1 12.7 2.3 8.5 12.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG68167.1 - 2.8 6.0 19.4 4 5.5 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4360 PF14273.6 GBG68168.1 - 2.3e-40 138.4 0.9 2.6e-40 138.2 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4524 PF15025.6 GBG68168.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) RVT_1 PF00078.27 GBG68169.1 - 2.3e-36 125.4 0.1 4.3e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68169.1 - 5.7e-28 97.3 0.2 1.5e-27 95.9 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68169.1 - 9.9e-26 89.7 0.0 2.9e-25 88.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG68169.1 - 0.00011 22.8 0.0 0.00028 21.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68169.1 - 0.00039 20.2 0.0 0.001 18.8 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG68169.1 - 0.00098 19.6 0.0 0.0036 17.8 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG68169.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG68169.1 - 0.048 13.4 0.1 0.18 11.6 0.1 1.9 1 1 0 1 1 1 0 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG68170.1 - 2.2e-25 89.2 0.0 3.1e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68170.1 - 4.6e-14 52.5 0.0 7.2e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68170.1 - 0.00014 21.6 0.1 0.33 10.6 0.1 2.3 2 0 0 2 2 2 2 Transposase DDE domain Lin-8 PF03353.15 GBG68170.1 - 0.12 12.0 9.7 0.17 11.4 9.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Na_trans_assoc PF06512.13 GBG68170.1 - 0.27 11.5 12.9 0.4 11.0 12.9 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Serinc PF03348.15 GBG68170.1 - 0.52 9.2 1.0 0.82 8.5 1.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) RNA_pol_Rpc4 PF05132.14 GBG68170.1 - 1.5 9.2 5.1 3.6 8.0 5.1 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 GBG68170.1 - 2.1 7.7 27.0 2.9 7.2 27.0 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG68170.1 - 2.2 8.0 21.3 3.1 7.5 21.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG68170.1 - 2.6 6.2 28.1 3.6 5.7 28.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG68170.1 - 4.9 6.5 18.5 7.4 5.9 18.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SAPS PF04499.15 GBG68170.1 - 9.2 4.9 9.9 13 4.5 9.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RVT_1 PF00078.27 GBG68171.1 - 2.3e-24 86.2 0.1 3.9e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68171.1 - 1.2e-20 73.3 0.1 2.8e-14 53.0 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68171.1 - 1.3e-10 41.5 0.0 1.9e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase MMR_HSR1 PF01926.23 GBG68171.1 - 2.4e-09 37.3 0.0 9e-05 22.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.27 GBG68171.1 - 2.9e-08 34.3 4.2 0.013 16.0 0.0 3.4 3 0 0 3 3 3 2 ABC transporter AAA_16 PF13191.6 GBG68171.1 - 8.3e-07 29.5 0.9 0.013 15.9 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 GBG68171.1 - 1.5e-06 28.6 0.0 0.012 15.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GBG68171.1 - 2e-06 27.8 0.0 0.0027 17.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 GBG68171.1 - 3.7e-05 23.8 0.4 0.13 12.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 GBG68171.1 - 0.0001 22.6 0.0 0.32 11.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 GBG68171.1 - 0.00012 22.5 5.3 0.24 11.8 0.0 4.1 4 1 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GBG68171.1 - 0.00024 21.3 0.0 0.95 9.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GBG68171.1 - 0.00025 20.8 0.0 0.68 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GBG68171.1 - 0.00028 20.8 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 GBG68171.1 - 0.00033 21.2 1.3 0.38 11.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 GBG68171.1 - 0.00044 20.0 0.0 0.32 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GBG68171.1 - 0.00055 19.2 0.0 0.72 9.0 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_29 PF13555.6 GBG68171.1 - 0.00058 19.5 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RuvB_N PF05496.12 GBG68171.1 - 0.00064 19.5 0.1 1.2 8.8 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GBG68171.1 - 0.0013 18.8 0.0 0.68 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GBG68171.1 - 0.0014 18.2 0.0 1.6 8.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 GBG68171.1 - 0.0017 18.5 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AIG1 PF04548.16 GBG68171.1 - 0.0018 17.7 10.3 0.19 11.0 0.0 3.7 3 1 0 3 3 2 2 AIG1 family T2SSE PF00437.20 GBG68171.1 - 0.0019 17.3 0.0 1.2 8.1 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.6 GBG68171.1 - 0.0019 18.4 2.2 3 8.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 GBG68171.1 - 0.0024 17.2 0.0 0.18 11.1 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 GBG68171.1 - 0.0028 17.4 0.0 0.033 13.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 GBG68171.1 - 0.0031 18.0 15.4 2.7 8.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 GBG68171.1 - 0.0044 17.4 0.3 2.3 8.6 0.0 3.1 4 0 0 4 4 2 1 AAA domain TsaE PF02367.17 GBG68171.1 - 0.0044 17.0 0.0 2.9 7.9 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GBG68171.1 - 0.0057 16.4 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 GBG68171.1 - 0.0077 16.2 5.0 1.1 9.2 0.0 3.3 4 0 0 4 4 2 2 ATPase domain predominantly from Archaea APS_kinase PF01583.20 GBG68171.1 - 0.0082 16.0 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 GBG68171.1 - 0.0093 15.6 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 GBG68171.1 - 0.0093 16.2 0.0 4.8 7.4 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Torsin PF06309.11 GBG68171.1 - 0.016 15.3 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Torsin Ras PF00071.22 GBG68171.1 - 0.018 14.6 0.1 3.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras family AAA_PrkA PF08298.11 GBG68171.1 - 0.023 13.6 0.0 3.7 6.4 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain Gtr1_RagA PF04670.12 GBG68171.1 - 0.026 13.9 0.3 0.9 8.8 0.0 3.0 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region cobW PF02492.19 GBG68171.1 - 0.038 13.6 0.3 5.7 6.5 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 GBG68171.1 - 0.06 13.4 4.4 4.7 7.3 0.0 3.3 3 0 0 3 3 2 0 Helicase HerA, central domain Mg_chelatase PF01078.21 GBG68171.1 - 0.065 12.6 0.0 13 5.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 GBG68171.1 - 0.081 12.5 0.0 5.1 6.7 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 GBG68171.1 - 0.095 12.6 0.9 17 5.2 0.0 2.9 3 0 0 3 3 2 0 NTPase G-alpha PF00503.20 GBG68171.1 - 0.3 10.2 2.6 0.95 8.6 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit Septin PF00735.18 GBG68171.1 - 0.46 9.7 4.3 2.6 7.3 0.0 2.8 3 0 0 3 3 2 0 Septin Dynamin_N PF00350.23 GBG68171.1 - 4.1 7.4 8.6 11 6.0 0.0 3.4 3 0 0 3 3 3 0 Dynamin family DUF4360 PF14273.6 GBG68172.1 - 5.4e-44 150.2 0.1 6.3e-44 150.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG68173.1 - 2.6e-41 141.5 0.7 2.9e-41 141.3 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG68174.1 - 1.8e-41 142.0 0.6 2e-41 141.8 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) LysE PF01810.18 GBG68175.1 - 0.058 12.8 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 LysE type translocator zf-C3HC4_3 PF13920.6 GBG68176.1 - 6.8e-05 22.7 7.5 0.00011 22.0 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH3_3 PF08239.11 GBG68176.1 - 0.01 16.1 1.3 0.045 14.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain Prok-RING_4 PF14447.6 GBG68176.1 - 0.15 12.0 7.0 0.34 10.8 7.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GBG68176.1 - 0.28 11.2 7.1 0.52 10.3 7.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG68176.1 - 0.79 9.6 4.8 2.2 8.2 4.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Retrotrans_gag PF03732.17 GBG68177.1 - 0.0034 17.6 0.2 0.017 15.4 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG68177.1 - 0.021 14.9 1.8 0.038 14.1 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Phage_lysozyme PF00959.19 GBG68177.1 - 0.15 12.5 1.0 0.66 10.4 0.0 2.5 3 0 0 3 3 3 0 Phage lysozyme Dev_Cell_Death PF10539.9 GBG68178.1 - 2.8e-08 33.7 0.0 6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Development and cell death domain RRM_1 PF00076.22 GBG68178.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_56 PF01630.18 GBG68178.1 - 0.16 10.9 0.6 0.24 10.3 0.6 1.1 1 0 0 1 1 1 0 Hyaluronidase RVT_1 PF00078.27 GBG68179.1 - 8.7e-30 103.9 0.0 1.9e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68179.1 - 9e-27 93.0 0.0 2.3e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68179.1 - 2.1e-24 85.8 0.0 5.3e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68179.1 - 1.6e-16 60.1 0.4 5.6e-16 58.4 0.4 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG68179.1 - 2e-06 28.3 0.0 5.6e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68179.1 - 1.9e-05 25.1 0.0 4.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG68179.1 - 9.2e-05 22.2 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG68179.1 - 0.0034 17.2 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG68179.1 - 0.35 11.2 5.8 3.3 8.1 0.1 3.7 4 0 0 4 4 4 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG68181.1 - 4.7e-29 101.5 0.7 1.5e-15 57.4 0.2 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68181.1 - 1.5e-24 85.9 0.0 3e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68181.1 - 2.7e-14 53.3 0.0 6.6e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68181.1 - 1.8e-11 44.3 0.0 8.5e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DUF659 PF04937.15 GBG68183.1 - 1.9e-29 102.5 0.2 5e-29 101.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG68183.1 - 0.019 14.7 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Apolipoprotein PF01442.18 GBG68184.1 - 9.4e-13 48.5 65.5 2.1e-08 34.3 24.1 3.8 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GBG68184.1 - 9.1e-07 29.3 63.5 0.58 10.7 2.4 8.3 2 2 5 7 7 7 6 YtxH-like protein DUF883 PF05957.13 GBG68184.1 - 0.00036 21.1 60.1 0.77 10.4 3.3 7.7 1 1 6 8 8 8 6 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.16 GBG68184.1 - 0.00071 19.6 62.2 0.2 11.8 0.3 9.2 5 4 4 9 9 9 4 Late embryogenesis abundant protein NDUFB11 PF17250.2 GBG68184.1 - 0.47 11.1 1.8 17 6.1 0.0 3.2 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Mu-like_Pro PF10123.9 GBG68186.1 - 0.0027 17.3 1.2 0.0029 17.2 1.2 1.1 1 0 0 1 1 1 1 Mu-like prophage I protein UPF0052 PF01933.18 GBG68186.1 - 0.091 12.0 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 PSK_trans_fac PF07704.11 GBG68186.1 - 1.7 9.4 16.8 3.7 8.4 9.2 2.3 1 1 1 2 2 2 0 Rv0623-like transcription factor FUSC PF04632.12 GBG68186.1 - 6.5 5.2 7.2 8.2 4.8 7.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family RT_RNaseH_2 PF17919.1 GBG68187.1 - 4.6e-31 106.8 0.0 1.1e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68187.1 - 5.7e-31 107.8 0.1 1.1e-30 106.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68187.1 - 2.1e-19 69.8 0.0 4.6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG68187.1 - 5.7e-05 23.6 0.0 0.00015 22.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68187.1 - 0.00054 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG68187.1 - 0.031 14.5 0.2 3.5 7.8 0.0 2.6 1 1 1 2 2 2 0 Integrase core domain DUF1564 PF07600.11 GBG68187.1 - 0.036 13.7 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) TOBE_2 PF08402.10 GBG68187.1 - 0.7 10.1 2.9 1.3 9.2 0.1 3.0 4 0 0 4 4 4 0 TOBE domain DUF2828 PF11443.8 GBG68187.1 - 2.8 5.9 12.7 4.5 5.3 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Integrase_H2C2 PF17921.1 GBG68188.1 - 1.4e-15 57.1 1.0 2.3e-15 56.5 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG68188.1 - 1.4e-09 38.1 0.0 4.7e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG68188.1 - 0.0053 16.9 0.2 0.012 15.8 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG68188.1 - 0.013 15.8 0.8 0.071 13.4 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein CENP-K PF11802.8 GBG68188.1 - 0.59 9.7 4.4 1 8.9 4.4 1.3 1 0 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 GBG68188.1 - 5.6 6.9 18.3 11 5.9 18.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Retrotrans_gag PF03732.17 GBG68189.1 - 0.006 16.8 2.7 0.022 15.0 0.1 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein CENP-K PF11802.8 GBG68189.1 - 0.13 11.8 4.3 0.23 11.0 4.3 1.3 1 0 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 GBG68189.1 - 1.2 9.1 18.3 1.7 8.6 18.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 GBG68189.1 - 7.5 5.8 22.9 7.4 5.8 20.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_2 PF07719.17 GBG68191.1 - 1.2e-10 40.7 3.2 0.0012 18.8 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG68191.1 - 1.4e-09 38.0 1.0 0.00082 20.0 0.1 4.4 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG68191.1 - 2.4e-08 33.6 0.4 0.1 12.9 0.0 4.8 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG68191.1 - 4.8e-08 33.4 2.6 0.012 16.1 0.6 3.7 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GBG68191.1 - 3.8e-07 30.6 0.0 0.15 12.8 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG68191.1 - 4.6e-05 23.5 0.3 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 GBG68191.1 - 9.4e-05 21.8 0.1 0.00019 20.8 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.8 GBG68191.1 - 0.00072 18.6 0.1 0.024 13.6 0.1 2.2 1 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 GBG68191.1 - 0.00081 19.1 2.0 0.13 12.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG68191.1 - 0.0021 18.3 2.4 2.2 8.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG68191.1 - 0.0045 16.9 0.1 1.6 9.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GBG68191.1 - 0.0064 17.1 0.6 65 4.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 GBG68191.1 - 0.013 15.9 0.1 1.2 9.6 0.0 2.3 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_12 PF13424.6 GBG68191.1 - 0.11 12.8 4.6 9.7 6.6 0.1 3.9 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GBG68191.1 - 0.13 12.0 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 0 TPR repeat PPR_2 PF13041.6 GBG68193.1 - 1.3e-14 54.1 0.3 0.0013 18.9 0.0 6.3 6 1 1 7 7 7 3 PPR repeat family PPR PF01535.20 GBG68193.1 - 2.7e-14 52.3 15.3 0.018 15.3 0.0 8.9 8 1 0 8 8 8 6 PPR repeat PPR_3 PF13812.6 GBG68193.1 - 4.2e-06 26.7 0.0 0.00044 20.3 0.0 3.6 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG68193.1 - 0.0014 18.3 11.6 0.16 11.7 0.0 5.6 6 0 0 6 6 6 2 PPR repeat SURF2 PF05477.11 GBG68194.1 - 3.1e-28 99.1 23.4 3.1e-28 99.1 23.4 3.6 2 1 0 2 2 2 1 Surfeit locus protein 2 (SURF2) DUF1192 PF06698.11 GBG68194.1 - 0.047 13.7 1.7 0.21 11.7 1.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) zf-BED PF02892.15 GBG68194.1 - 0.71 9.9 4.7 0.4 10.7 1.6 2.3 2 0 0 2 2 2 0 BED zinc finger Histone PF00125.24 GBG68195.1 - 2.3e-21 76.5 0.5 2.3e-21 76.5 0.5 4.6 2 1 2 4 4 4 1 Core histone H2A/H2B/H3/H4 NB-ARC PF00931.22 GBG68196.1 - 2.5e-33 115.3 0.0 5.1e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain LRR_4 PF12799.7 GBG68196.1 - 1.1e-21 76.6 42.3 5.8e-05 23.4 3.1 10.2 5 3 4 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG68196.1 - 6.3e-15 54.7 45.7 4.2e-05 23.2 1.6 8.7 5 2 5 10 10 10 9 Leucine rich repeat LRR_1 PF00560.33 GBG68196.1 - 0.00043 20.5 39.6 2.3 9.1 0.1 11.4 13 0 0 13 13 13 4 Leucine Rich Repeat NACHT PF05729.12 GBG68196.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 GBG68196.1 - 0.15 12.5 0.0 0.47 10.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4655 PF15548.6 GBG68196.1 - 0.85 8.5 5.3 1.3 7.9 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) TFIIA PF03153.13 GBG68199.1 - 0.00099 19.2 16.9 0.0012 19.0 16.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3090 PF11290.8 GBG68199.1 - 0.019 14.8 5.5 0.036 13.9 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) FAM199X PF15814.5 GBG68199.1 - 0.16 11.0 7.8 0.055 12.5 4.9 1.7 1 1 0 1 1 1 0 Protein family FAM199X Presenilin PF01080.17 GBG68199.1 - 0.4 9.4 9.4 0.57 8.9 9.4 1.2 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 GBG68199.1 - 1.4 7.8 31.0 2.2 7.2 31.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PAT1 PF09770.9 GBG68199.1 - 1.6 6.9 20.2 2.1 6.5 20.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 GBG68199.1 - 2.5 6.7 12.7 3.9 6.0 12.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM76 PF16046.5 GBG68200.1 - 0.0037 16.7 8.5 0.0046 16.4 8.5 1.2 1 0 0 1 1 1 1 FAM76 protein TAF4 PF05236.14 GBG68200.1 - 0.0066 16.2 13.3 0.0082 15.9 13.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CDC45 PF02724.14 GBG68200.1 - 0.29 9.4 10.3 0.29 9.4 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PspB PF06667.12 GBG68200.1 - 1.4 9.1 17.1 5.4 7.2 0.4 3.7 3 1 0 3 3 3 0 Phage shock protein B Presenilin PF01080.17 GBG68200.1 - 2 7.1 11.7 2.4 6.9 11.7 1.1 1 0 0 1 1 1 0 Presenilin DUF4666 PF15697.5 GBG68200.1 - 3.7 8.3 9.9 14 6.4 9.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) Peptidase_S64 PF08192.11 GBG68200.1 - 4.9 5.5 7.2 5.8 5.3 7.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Sec62 PF03839.16 GBG68200.1 - 9.5 5.7 6.5 13 5.3 6.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 NB-ARC PF00931.22 GBG68201.1 - 1.6e-25 89.7 0.0 2e-14 53.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain LRR_4 PF12799.7 GBG68201.1 - 3.1e-24 84.7 29.6 2e-05 24.8 0.3 10.0 6 3 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG68201.1 - 2.8e-21 75.1 27.5 1.6e-05 24.6 0.3 7.8 6 1 1 8 8 8 5 Leucine rich repeat LRR_9 PF14580.6 GBG68201.1 - 0.0025 17.4 1.2 0.78 9.2 0.1 2.6 2 0 0 2 2 2 2 Leucine-rich repeat ADH_zinc_N PF00107.26 GBG68201.1 - 0.033 14.2 0.0 0.25 11.3 0.0 2.4 3 0 0 3 3 3 0 Zinc-binding dehydrogenase LRR_1 PF00560.33 GBG68201.1 - 0.035 14.6 35.9 0.15 12.7 0.3 11.7 14 2 0 14 14 14 0 Leucine Rich Repeat LRR_6 PF13516.6 GBG68201.1 - 4 7.7 15.0 30 5.0 0.1 7.4 7 0 0 7 7 7 0 Leucine Rich repeat RVT_1 PF00078.27 GBG68202.1 - 0.0033 17.0 0.0 0.0068 15.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) alpha-hel2 PF14456.6 GBG68202.1 - 0.13 11.6 2.9 0.24 10.7 2.9 1.4 1 0 0 1 1 1 0 Alpha-helical domain 2 RT_RNaseH_2 PF17919.1 GBG68203.1 - 1.7e-29 101.8 0.0 3.3e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68203.1 - 6.2e-27 93.9 0.0 1.1e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68203.1 - 6.4e-05 22.6 0.2 0.00012 21.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG68203.1 - 0.0059 17.2 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG68203.1 - 0.0066 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68203.1 - 0.17 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG68204.1 - 5.8e-19 68.3 0.0 2e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68204.1 - 5.6e-16 58.4 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG68204.1 - 1.9e-06 28.3 0.1 4e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68204.1 - 8.3e-05 23.2 0.1 0.00018 22.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68204.1 - 0.0067 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68204.1 - 0.0085 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG68205.1 - 0.0019 18.7 0.1 0.0052 17.3 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68205.1 - 0.012 16.2 0.0 0.03 15.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG68205.1 - 0.045 13.4 1.3 0.11 12.2 0.3 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG68205.1 - 0.22 11.3 0.1 0.39 10.5 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG68206.1 - 8e-19 67.5 1.8 2.8e-18 65.8 0.6 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG68206.1 - 9.6e-14 51.2 0.0 2.4e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68206.1 - 4.6e-13 49.4 0.0 1.3e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG68206.1 - 1.6e-11 44.4 0.0 7.9e-11 42.2 0.0 2.3 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68206.1 - 1.5e-05 24.7 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG68206.1 - 0.047 13.9 0.3 0.047 13.9 0.3 2.0 2 0 0 2 2 2 0 H2C2 zinc finger Glyco_transf_4 PF13439.6 GBG68206.1 - 0.073 13.1 0.0 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 RT_RNaseH_2 PF17919.1 GBG68207.1 - 1.9e-22 79.2 0.0 4.6e-21 74.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68207.1 - 4.5e-22 78.3 0.0 3.9e-21 75.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG68207.1 - 1.6e-07 31.8 0.0 3.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG68207.1 - 1.8e-06 27.6 0.0 4.3e-06 26.4 0.0 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG68207.1 - 2.2e-06 28.2 0.0 4.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68207.1 - 0.0009 19.0 0.1 0.0016 18.2 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68207.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG68208.1 - 1.2e-28 99.4 0.0 3e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68208.1 - 3.2e-28 97.7 0.0 7.5e-28 96.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68208.1 - 0.033 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG68208.1 - 0.097 12.3 10.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Ribosomal_L34e PF01199.18 GBG68208.1 - 0.11 12.8 0.8 0.32 11.3 0.8 1.8 1 0 0 1 1 1 0 Ribosomal protein L34e PA26 PF04636.13 GBG68208.1 - 0.66 8.8 6.2 1 8.2 6.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF5401 PF17380.2 GBG68208.1 - 1.8 6.6 15.3 2.5 6.0 15.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Nop53 PF07767.11 GBG68208.1 - 9.3 5.5 18.2 15 4.9 18.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) WD40 PF00400.32 GBG68209.1 - 7.3e-08 33.0 1.7 4.3e-06 27.4 0.2 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat TIMELESS_C PF05029.13 GBG68209.1 - 0.0051 16.0 0.3 0.0051 16.0 0.3 1.9 2 0 0 2 2 2 1 Timeless protein C terminal region RE_BstXI PF09552.10 GBG68209.1 - 0.0085 15.3 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 1 BstXI restriction endonuclease FAM176 PF14851.6 GBG68209.1 - 1.2 8.8 13.3 0.56 9.9 4.6 2.7 2 0 0 2 2 2 0 FAM176 family DUF2052 PF09747.9 GBG68209.1 - 3.5 7.7 21.8 0.1 12.7 4.9 3.2 4 0 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) Mak16 PF04874.14 GBG68209.1 - 7.3 7.3 22.4 1.2 9.8 11.2 2.9 2 0 0 2 2 2 0 Mak16 protein C-terminal region RVT_1 PF00078.27 GBG68210.1 - 1.1e-12 48.0 0.1 2.1e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68215.1 - 1.4e-29 102.1 0.1 4.5e-29 100.4 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68215.1 - 3.1e-28 98.8 0.1 5.2e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68215.1 - 3.5e-26 91.5 0.0 2.6e-25 88.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68215.1 - 2.9e-17 62.5 0.6 5.9e-17 61.5 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68215.1 - 3e-12 46.8 0.0 6.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG68215.1 - 0.031 14.6 0.2 0.11 12.8 0.2 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein RLL PF10036.9 GBG68215.1 - 0.055 13.3 2.8 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein rve_3 PF13683.6 GBG68215.1 - 0.16 11.8 0.2 17 5.3 0.0 3.0 2 0 0 2 2 2 0 Integrase core domain Lipase_3 PF01764.25 GBG68218.1 - 2.2e-07 30.9 0.0 1.9e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) Ricin_B_lectin PF00652.22 GBG68219.1 - 0.0038 17.5 1.6 0.029 14.6 0.2 2.5 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain Pkinase_Tyr PF07714.17 GBG68220.1 - 2.6e-40 138.4 0.0 3.4e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG68220.1 - 3.4e-38 131.5 0.0 4.5e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 GBG68220.1 - 9.7e-13 47.7 22.4 7e-06 25.7 0.2 4.6 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GBG68220.1 - 4.6e-11 42.8 27.1 0.00093 19.5 0.2 6.0 2 1 3 7 7 7 6 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GBG68220.1 - 4.8e-06 26.8 0.3 1.2e-05 25.5 0.3 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GBG68220.1 - 0.0011 19.2 21.4 9.1 7.3 0.1 9.2 10 1 0 10 10 10 1 Leucine Rich Repeat Nop53 PF07767.11 GBG68221.1 - 0.25 10.7 18.1 0.33 10.3 18.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SAPS PF04499.15 GBG68221.1 - 8.7 5.0 8.4 12 4.5 8.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Kinesin PF00225.23 GBG68222.1 - 7e-39 133.7 0.0 1e-25 90.4 0.0 2.7 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 GBG68222.1 - 1.6e-27 96.3 0.3 6.2e-25 87.9 0.0 3.0 3 0 0 3 3 3 2 Microtubule binding PRIMA1 PF16101.5 GBG68222.1 - 2.1 8.4 4.3 5.8 7.0 4.3 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Baculo_PEP_C PF04513.12 GBG68222.1 - 4.5 7.3 11.5 11 6.1 0.0 4.7 4 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus TAtT PF16811.5 GBG68223.1 - 0.028 13.7 2.0 3.6 6.8 0.0 2.1 2 0 0 2 2 2 0 TRAP transporter T-component TMPIT PF07851.13 GBG68223.1 - 1.2 8.3 2.5 1.6 7.9 2.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein RVT_1 PF00078.27 GBG68225.1 - 2.9e-29 102.2 0.1 1.3e-28 100.0 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG68225.1 - 8.4e-26 90.5 0.0 2.4e-25 89.1 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 GBG68225.1 - 1.2e-22 79.8 0.0 5.9e-22 77.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68225.1 - 2.6e-22 79.1 0.0 7.9e-22 77.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Plant_tran PF04827.14 GBG68225.1 - 1.7e-07 31.1 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein RVP_2 PF08284.11 GBG68225.1 - 0.0053 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG68225.1 - 0.012 15.9 2.0 0.047 14.0 0.0 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein Myb_DNA-binding PF00249.31 GBG68226.1 - 1.2e-18 67.1 7.4 1.5e-10 41.1 0.8 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG68226.1 - 5.5e-13 48.9 2.8 9.1e-09 35.4 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG68227.1 - 2e-31 108.0 0.0 4.2e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68227.1 - 2.7e-27 95.1 0.1 6.5e-27 93.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68227.1 - 1.7e-17 63.3 0.1 3.5e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68227.1 - 2.3e-12 47.1 0.0 7e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG68227.1 - 0.0006 20.3 0.0 0.0032 18.0 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68227.1 - 0.0011 19.6 0.0 0.0043 17.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG68227.1 - 0.0054 16.9 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG68227.1 - 0.012 15.9 1.9 0.035 14.4 0.1 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein DUF1758 PF05585.12 GBG68227.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) TMF_DNA_bd PF12329.8 GBG68227.1 - 6.7 6.8 10.5 29 4.8 8.1 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RVT_1 PF00078.27 GBG68228.1 - 2.4e-15 56.7 0.1 4.3e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG68228.1 - 1.7e-05 25.0 0.0 4.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Ribosomal_L30 PF00327.20 GBG68229.1 - 0.081 12.8 0.1 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e Fe-ADH PF00465.19 GBG68229.1 - 0.15 10.8 0.8 0.32 9.7 0.4 1.7 1 1 1 2 2 2 0 Iron-containing alcohol dehydrogenase Lipoprotein_6 PF01441.19 GBG68229.1 - 0.3 11.1 3.8 0.49 10.4 2.8 1.7 1 1 1 2 2 2 0 Lipoprotein zf-CCHC PF00098.23 GBG68230.1 - 2.6e-05 24.1 1.0 2.6e-05 24.1 1.0 1.9 2 0 0 2 2 2 1 Zinc knuckle ZapB PF06005.12 GBG68230.1 - 0.0074 16.7 0.1 0.0074 16.7 0.1 3.1 2 1 1 3 3 3 1 Cell division protein ZapB zf-CCHC_6 PF15288.6 GBG68230.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Zinc knuckle LMBR1 PF04791.16 GBG68230.1 - 0.22 10.4 4.1 0.29 10.0 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1943 PF09172.11 GBG68230.1 - 4.7 6.4 4.9 6.7 5.8 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Fib_alpha PF08702.10 GBG68230.1 - 6.1 7.0 12.3 2.7 8.2 8.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlgT_C PF16538.5 GBG68231.1 - 0.088 13.3 3.0 11 6.7 0.8 3.0 3 1 1 4 4 4 0 Flagellar assembly protein T, C-terminal domain Peptidase_C92 PF05708.12 GBG68231.1 - 3.2 7.8 6.0 28 4.8 0.1 3.1 2 1 0 3 3 3 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family FAD_binding_3 PF01494.19 GBG68232.1 - 1.1e-13 51.2 5.1 1.4e-13 50.8 2.3 2.3 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GBG68232.1 - 2.2e-06 27.1 2.5 0.00027 20.3 0.4 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GBG68232.1 - 3.8e-06 27.0 0.3 2.7e-05 24.3 0.5 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GBG68232.1 - 0.00051 19.2 1.3 0.0013 17.9 1.3 1.7 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 GBG68232.1 - 0.0049 16.2 0.4 0.0094 15.3 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GBG68232.1 - 0.0055 17.2 0.5 0.014 15.9 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GBG68232.1 - 0.011 14.6 1.2 0.095 11.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 GBG68232.1 - 0.012 15.3 2.0 0.03 13.9 1.7 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 GBG68232.1 - 0.036 13.2 0.2 0.059 12.5 0.2 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 GBG68232.1 - 0.056 12.7 0.2 0.12 11.6 0.2 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 GBG68232.1 - 0.13 10.9 2.7 0.085 11.5 0.6 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 GBG68232.1 - 0.15 11.3 0.7 0.23 10.6 0.7 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase N2227 PF07942.12 GBG68232.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Lycopene_cycl PF05834.12 GBG68232.1 - 1.6 7.7 5.7 6.5 5.7 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein DUF563 PF04577.14 GBG68233.1 - 9.2e-16 58.6 0.0 2.5e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF563) CofC PF01983.16 GBG68233.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Guanylyl transferase CofC like Phage_Gp23 PF10669.9 GBG68233.1 - 0.15 12.4 4.4 0.39 11.1 4.4 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) gag-asp_proteas PF13975.6 GBG68234.1 - 3.7e-06 27.4 0.3 1.3e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68234.1 - 2.3e-05 25.0 0.1 7.7e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG68234.1 - 0.0087 16.4 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Chorismate_bind PF00425.18 GBG68235.1 - 5.9e-87 291.5 0.0 8.8e-87 290.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 GBG68235.1 - 1.3e-35 122.9 0.0 6.9e-26 91.2 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 GBG68235.1 - 9.3e-15 55.1 0.0 2.5e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 GBG68235.1 - 0.0021 17.9 0.0 0.076 12.8 0.0 2.3 2 0 0 2 2 2 1 Peptidase C26 DUF563 PF04577.14 GBG68236.1 - 8.6e-17 62.0 0.0 2.8e-16 60.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) GRP PF07172.11 GBG68236.1 - 0.017 15.8 6.2 0.017 15.8 6.2 3.0 4 0 0 4 4 4 0 Glycine rich protein family RT_RNaseH_2 PF17919.1 GBG68237.1 - 9.2e-26 89.8 0.0 4.5e-25 87.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68237.1 - 3.1e-24 85.7 0.0 5.7e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68237.1 - 1.9e-23 82.7 0.0 5.9e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG68237.1 - 8.8e-05 23.0 0.0 0.00026 21.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68237.1 - 0.0002 21.9 0.0 0.00046 20.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68237.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG68237.1 - 0.0027 17.5 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_M8 PF01457.16 GBG68238.1 - 1.5e-44 152.6 3.4 3.8e-44 151.3 3.4 1.6 1 0 0 1 1 1 1 Leishmanolysin EGF_Tenascin PF18720.1 GBG68238.1 - 0.0038 17.2 13.7 0.0038 17.2 13.7 3.3 3 0 0 3 3 3 1 Tenascin EGF domain EGF_2 PF07974.13 GBG68238.1 - 0.0089 16.4 13.9 0.0089 16.4 13.9 3.3 3 0 0 3 3 3 1 EGF-like domain Peptidase_C1 PF00112.23 GBG68239.1 - 4.4e-66 223.1 5.3 5.5e-66 222.8 5.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 GBG68239.1 - 4.4e-07 29.7 0.0 8.9e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 GBG68239.1 - 1 8.1 3.1 15 4.2 0.1 2.1 2 0 0 2 2 2 0 Peptidase C1-like family CKS PF01111.19 GBG68240.1 - 6.9e-26 90.3 0.2 8.7e-26 90.0 0.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit RGP PF03214.13 GBG68241.1 - 5.5e-175 581.5 0.0 6.3e-175 581.3 0.0 1.0 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide Glycos_transf_2 PF00535.26 GBG68241.1 - 0.0022 17.8 0.1 0.028 14.2 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GBG68241.1 - 0.026 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Myb_DNA-bind_4 PF13837.6 GBG68242.1 - 5.3e-08 33.1 1.0 7.2e-08 32.7 0.6 1.5 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG68242.1 - 0.01 16.1 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MCD PF05292.11 GBG68243.1 - 8.2e-31 107.5 0.0 1.5e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 GBG68243.1 - 2.1e-12 47.0 0.0 1.9e-11 43.9 0.0 2.6 3 0 0 3 3 3 1 Malonyl-CoA decarboxylase N-terminal domain Pox_A_type_inc PF04508.12 GBG68243.1 - 0.8 9.7 3.8 0.34 10.8 0.7 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat MCD PF05292.11 GBG68244.1 - 8.4e-31 107.5 0.2 1e-30 107.2 0.2 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain RVT_1 PF00078.27 GBG68245.1 - 3.1e-33 115.2 0.0 7.3e-33 113.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68245.1 - 1.2e-30 105.5 0.0 4.4e-30 103.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68245.1 - 1e-29 102.9 0.0 2.2e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG68245.1 - 2.5e-09 37.0 0.0 4.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68245.1 - 5.2e-06 27.0 0.0 1.1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG68245.1 - 4.8e-05 23.2 0.5 0.00028 20.7 0.0 2.3 3 0 0 3 3 3 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG68245.1 - 0.00024 21.6 0.0 0.00055 20.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG68245.1 - 0.0012 18.9 0.1 0.0024 17.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Peptidase_A3 PF02160.15 GBG68245.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Clat_adaptor_s PF01217.20 GBG68246.1 - 1.5e-46 157.8 2.1 2.4e-46 157.2 2.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BUD22 PF09073.10 GBG68246.1 - 0.53 9.6 3.1 0.69 9.2 3.1 1.1 1 0 0 1 1 1 0 BUD22 DUF3246 PF11596.8 GBG68246.1 - 0.57 9.6 6.6 3.6 6.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DUF4611 PF15387.6 GBG68246.1 - 2.6 8.3 12.8 6.4 7.1 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Spt5_N PF11942.8 GBG68246.1 - 8.1 7.5 15.2 14 6.7 1.0 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal OKR_DC_1 PF01276.20 GBG68247.1 - 5.5e-65 219.7 0.0 2.7e-64 217.4 0.0 1.8 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 GBG68247.1 - 3.9e-10 40.1 0.0 8.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain GHMP_kinases_N PF00288.26 GBG68247.1 - 4.2e-09 36.5 10.1 5.4e-08 32.9 7.8 3.5 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GBG68247.1 - 3.1e-08 33.9 1.9 6.8e-08 32.8 0.3 2.6 2 0 0 2 2 2 1 GHMP kinases C terminal SepSecS PF05889.13 GBG68247.1 - 9.9e-08 31.1 0.0 1.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 GBG68247.1 - 0.00025 20.3 0.0 0.0019 17.4 0.0 2.3 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GBG68247.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GBG68247.1 - 0.002 17.1 0.0 0.0057 15.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GBG68247.1 - 0.0025 16.4 0.0 0.006 15.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GBG68247.1 - 0.0044 16.4 0.1 0.0078 15.6 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GTP_EFTU PF00009.27 GBG68250.1 - 1.4e-50 171.5 0.0 2.1e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 GBG68250.1 - 3.2e-34 118.1 6.6 5.2e-34 117.4 6.6 1.3 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 GBG68250.1 - 1.5e-23 82.6 0.0 3.3e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 GBG68250.1 - 6.5e-15 55.0 0.0 1.9e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 GBG68250.1 - 1.4e-11 44.6 0.0 3.9e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG68250.1 - 5.5e-05 23.2 0.0 9.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 GBG68250.1 - 0.0001 22.3 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Roc PF08477.13 GBG68250.1 - 0.037 14.2 0.0 0.64 10.2 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 GBG68250.1 - 0.13 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Septin Ras PF00071.22 GBG68250.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 1 1 0 1 1 1 0 Ras family Integrase_H2C2 PF17921.1 GBG68251.1 - 5e-20 71.4 0.6 1e-19 70.4 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG68251.1 - 2.1e-15 56.9 0.2 6.1e-15 55.4 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68251.1 - 2.3e-15 56.9 0.1 4.8e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Nodulin-like PF06813.13 GBG68251.1 - 7.3e-14 51.9 2.1 1.7e-12 47.4 1.8 2.1 2 0 0 2 2 2 1 Nodulin-like RT_RNaseH_2 PF17919.1 GBG68251.1 - 3.8e-07 30.1 0.0 9.8e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG68251.1 - 0.00064 19.9 0.0 0.0019 18.4 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger SID-1_RNA_chan PF13965.6 GBG68252.1 - 0.45 8.9 0.0 0.37 9.1 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1168 PF06658.12 GBG68252.1 - 1.8 8.4 35.8 2.8 7.8 35.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF4746 PF15928.5 GBG68252.1 - 7 6.0 22.9 8.2 5.7 22.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MFS_1 PF07690.16 GBG68253.1 - 0.00034 19.6 2.6 0.00041 19.4 2.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 GBG68254.1 - 1.1e-58 198.8 1.8 1.1e-58 198.8 1.8 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GBG68254.1 - 1.4e-32 112.2 1.0 4.2e-30 104.2 0.1 3.9 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GBG68254.1 - 7.8e-15 55.2 5.6 3e-13 50.1 0.0 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GBG68254.1 - 1.2e-07 31.5 1.3 1.3e-05 24.8 2.9 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG68254.1 - 4.2e-07 29.4 12.4 0.0006 19.0 1.4 2.7 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 GBG68254.1 - 4.6e-06 26.0 6.9 2.9e-05 23.3 5.1 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 GBG68254.1 - 0.00021 20.6 0.3 0.00057 19.1 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 GBG68254.1 - 0.0032 16.7 1.1 0.0092 15.3 0.7 2.0 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 GBG68254.1 - 0.0084 16.0 0.5 4.5 7.1 0.0 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 GBG68254.1 - 0.013 14.7 5.7 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GBG68254.1 - 0.048 13.2 14.8 0.7 9.4 7.7 3.2 2 1 0 3 3 3 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 GBG68254.1 - 0.053 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 GBG68254.1 - 0.14 10.8 3.1 5.8 5.5 2.5 2.4 2 0 0 2 2 2 0 HI0933-like protein TP2 PF01254.18 GBG68255.1 - 0.0017 19.0 10.0 0.0024 18.5 10.0 1.2 1 0 0 1 1 1 1 Nuclear transition protein 2 DUF2333 PF10095.9 GBG68255.1 - 0.052 12.6 2.5 0.078 12.0 2.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Peptidase_S49_N PF08496.10 GBG68255.1 - 0.054 13.6 6.6 0.083 12.9 6.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BCS1_N PF08740.11 GBG68255.1 - 0.11 12.5 2.5 0.17 11.9 2.2 1.5 1 1 0 1 1 1 0 BCS1 N terminal DUF3464 PF11947.8 GBG68255.1 - 0.26 11.1 6.3 0.32 10.7 6.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4604 PF15377.6 GBG68255.1 - 0.5 10.8 15.8 0.88 10.0 15.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) eIF_4EBP PF05456.11 GBG68255.1 - 0.76 9.7 7.6 1.1 9.2 6.9 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) YscJ_FliF_C PF08345.11 GBG68256.1 - 0.12 12.7 18.5 0.098 13.0 14.5 2.2 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal DUF3807 PF12720.7 GBG68256.1 - 0.36 11.1 7.5 0.65 10.3 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 GBG68256.1 - 0.51 9.0 8.9 0.7 8.6 8.9 1.2 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.13 GBG68256.1 - 0.58 8.7 10.1 0.74 8.3 10.1 1.1 1 0 0 1 1 1 0 Utp14 protein Zip PF02535.22 GBG68256.1 - 0.76 8.9 7.1 1.2 8.3 7.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 GBG68256.1 - 1.3 8.0 8.6 1.7 7.6 8.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 GBG68256.1 - 1.3 9.1 11.1 2.5 8.1 11.1 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family NPR3 PF03666.13 GBG68256.1 - 1.6 7.5 13.3 0.33 9.7 10.1 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 TCP PF03634.13 GBG68256.1 - 1.7 9.2 8.4 4.3 7.9 8.4 1.7 1 0 0 1 1 1 0 TCP family transcription factor Tim54 PF11711.8 GBG68256.1 - 5.7 5.6 7.9 1.9 7.2 4.2 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 ALMT PF11744.8 GBG68256.1 - 6.4 5.5 9.3 0.47 9.2 4.5 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter F-box-like PF12937.7 GBG68257.1 - 5.2e-06 26.2 0.1 1.2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG68257.1 - 0.033 14.1 0.1 0.08 12.9 0.1 1.7 1 0 0 1 1 1 0 F-box domain SecA_DEAD PF07517.14 GBG68258.1 - 6.3e-125 416.3 0.0 9.4e-125 415.7 0.0 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 GBG68258.1 - 2.7e-52 177.8 0.0 4.8e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 GBG68258.1 - 7.2e-35 120.0 1.6 1.9e-34 118.7 0.2 2.4 3 0 0 3 3 3 1 SecA preprotein cross-linking domain DEAD PF00270.29 GBG68258.1 - 4.7e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SecA_DEAD PF07517.14 GBG68259.1 - 5.5e-125 416.5 0.0 8.3e-125 415.9 0.0 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 GBG68259.1 - 2.3e-52 178.0 0.0 4.3e-52 177.1 0.0 1.5 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 GBG68259.1 - 6.2e-35 120.2 1.7 1.7e-34 118.8 0.2 2.5 3 0 0 3 3 3 1 SecA preprotein cross-linking domain DEAD PF00270.29 GBG68259.1 - 4.2e-07 29.9 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SecA_DEAD PF07517.14 GBG68260.1 - 5.2e-125 416.5 0.0 7.8e-125 416.0 0.0 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 GBG68260.1 - 2.3e-52 178.0 0.0 4.1e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 GBG68260.1 - 6.1e-35 120.2 1.6 1.7e-34 118.8 0.2 2.4 3 0 0 3 3 3 1 SecA preprotein cross-linking domain DEAD PF00270.29 GBG68260.1 - 4.1e-07 29.9 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase MMU163 PF17119.5 GBG68261.1 - 0.66 9.1 3.7 0.98 8.5 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Presenilin PF01080.17 GBG68261.1 - 1.1 8.0 4.7 1.3 7.7 4.7 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 GBG68261.1 - 7.5 5.0 8.8 9 4.7 8.8 1.1 1 0 0 1 1 1 0 Macoilin family Myb_DNA-binding PF00249.31 GBG68262.1 - 4e-57 190.2 22.6 3.8e-15 55.8 0.1 6.1 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG68262.1 - 1.1e-40 137.7 11.5 2.6e-13 50.0 0.2 6.2 1 1 4 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 GBG68262.1 - 6e-06 26.3 0.0 5.5 7.1 0.0 4.4 4 0 0 4 4 4 3 SLIDE Ribosomal_L36e PF01158.18 GBG68263.1 - 5.9e-43 145.0 8.8 8.5e-43 144.5 8.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L36e SlyX PF04102.12 GBG68265.1 - 0.26 11.9 0.7 1.5 9.5 0.2 2.4 3 0 0 3 3 3 0 SlyX RVT_1 PF00078.27 GBG68266.1 - 1.6e-09 37.6 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG68266.1 - 1.1e-06 29.1 0.1 2.6e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG68266.1 - 0.00017 21.3 0.2 0.00031 20.5 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG68266.1 - 0.00026 21.6 0.2 0.00055 20.5 0.2 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68266.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG68266.1 - 0.025 14.2 0.3 0.062 13.0 0.3 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DUF659 PF04937.15 GBG68268.1 - 5e-22 78.4 0.0 9.5e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG68268.1 - 0.0012 18.6 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TMEM144 PF07857.12 GBG68271.1 - 1e-19 70.7 18.1 1.3e-13 50.6 0.2 2.1 2 0 0 2 2 2 2 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 GBG68271.1 - 1.2e-07 31.4 17.7 2.1e-07 30.6 4.2 2.2 2 0 0 2 2 2 2 Sugar transport protein EamA PF00892.20 GBG68271.1 - 0.031 14.5 40.3 0.61 10.3 17.8 2.4 2 0 0 2 2 2 0 EamA-like transporter family PBP_N PF17093.5 GBG68271.1 - 0.6 10.4 2.5 1.5 9.1 2.5 1.6 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DUF3591 PF12157.8 GBG68272.1 - 1.1e-131 439.5 0.0 3.4e-131 437.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 GBG68272.1 - 3.3e-18 65.5 0.1 8e-18 64.3 0.1 1.6 1 0 0 1 1 1 1 Bromodomain ubiquitin PF00240.23 GBG68272.1 - 2.1e-09 37.0 0.0 4.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf-CCHC_6 PF15288.6 GBG68272.1 - 0.00088 19.1 2.0 0.0038 17.0 1.2 2.4 2 0 0 2 2 2 1 Zinc knuckle Rad60-SLD PF11976.8 GBG68272.1 - 0.048 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Tox-WTIP PF15654.6 GBG68272.1 - 0.13 12.7 0.1 0.64 10.5 0.1 2.2 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif DUF2407 PF10302.9 GBG68272.1 - 0.24 12.0 0.5 0.86 10.2 0.0 2.2 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain tRNA_int_end_N2 PF12928.7 GBG68273.1 - 8.5e-15 54.7 0.3 2.5e-14 53.2 0.3 1.9 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Retrotrans_gag PF03732.17 GBG68273.1 - 0.03 14.6 0.1 0.03 14.6 0.1 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein DUF4407 PF14362.6 GBG68273.1 - 0.32 10.3 2.6 3.1 7.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CLZ PF16526.5 GBG68273.1 - 2.7 8.4 7.2 0.32 11.4 0.5 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_TATA_bd PF12325.8 GBG68273.1 - 3.5 7.9 8.3 0.33 11.2 0.3 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding tRNA_int_end_N2 PF12928.7 GBG68274.1 - 2e-05 24.7 0.3 6.3e-05 23.1 0.3 2.0 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Retrotrans_gag PF03732.17 GBG68274.1 - 0.0071 16.6 1.2 0.023 15.0 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG68274.1 - 0.29 10.4 3.2 2.4 7.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 GBG68274.1 - 1.9 8.7 8.3 0.25 11.6 0.3 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 GBG68274.1 - 6.7 7.1 9.1 0.27 11.6 0.6 3.0 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ribosomal_L27A PF00828.19 GBG68275.1 - 3.8e-35 121.3 1.3 8.6e-35 120.2 1.3 1.6 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CAP_GLY PF01302.25 GBG68275.1 - 1.6e-18 66.5 1.9 3e-18 65.6 1.9 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 GBG68275.1 - 1.9e-12 47.2 12.8 0.00028 21.2 0.2 4.6 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GBG68275.1 - 4e-10 39.5 0.1 2.3e-05 24.0 0.0 3.0 1 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 GBG68275.1 - 0.00061 19.5 14.5 0.093 12.5 0.1 4.7 2 2 2 4 4 4 3 Leucine rich repeat RT_RNaseH PF17917.1 GBG68278.1 - 1.5e-23 83.1 0.0 3.6e-23 81.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68278.1 - 1.2e-21 76.6 0.0 5.2e-21 74.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG68278.1 - 0.0033 18.0 0.0 0.0092 16.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG68278.1 - 0.011 15.5 0.2 0.021 14.6 0.2 1.4 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG68278.1 - 0.027 15.1 0.0 2 9.1 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease DUF659 PF04937.15 GBG68280.1 - 1.9e-11 44.0 0.0 8.2e-11 42.0 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG68280.1 - 0.018 15.3 0.1 0.068 13.5 0.1 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein LPD3 PF18798.1 GBG68280.1 - 0.14 12.4 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 3 RT_RNaseH PF17917.1 GBG68281.1 - 8.8e-17 61.3 0.0 2.6e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68281.1 - 2.3e-16 59.7 0.0 6.1e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68281.1 - 7.3e-16 58.0 0.1 1.7e-15 56.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG68281.1 - 2e-11 43.8 0.0 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ubiquitin PF00240.23 GBG68281.1 - 2.9e-10 39.8 0.3 1.4e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family rve PF00665.26 GBG68281.1 - 0.01 16.0 0.0 0.037 14.2 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain TUG-UBL1 PF11470.8 GBG68281.1 - 0.039 14.2 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 TUG ubiquitin-like domain PH_11 PF15413.6 GBG68281.1 - 0.06 13.8 0.8 15 6.1 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain CENP-K PF11802.8 GBG68281.1 - 0.21 11.1 2.5 0.37 10.3 2.5 1.3 1 0 0 1 1 1 0 Centromere-associated protein K UCH PF00443.29 GBG68282.1 - 4.7e-42 144.3 0.0 7.2e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG68282.1 - 9e-25 87.9 0.0 3.2e-24 86.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4187 PF13821.6 GBG68282.1 - 0.0094 15.7 0.9 0.043 13.6 0.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) UCH PF00443.29 GBG68283.1 - 4.3e-42 144.4 0.0 6.6e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG68283.1 - 2.6e-24 86.4 0.0 9e-24 84.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4187 PF13821.6 GBG68283.1 - 0.0094 15.7 0.9 0.043 13.6 0.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) BCLP PF12304.8 GBG68284.1 - 0.00022 20.8 0.2 0.069 12.7 0.0 2.4 2 0 0 2 2 2 2 Beta-casein like protein Clathrin_H_link PF13838.6 GBG68284.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Clathrin-H-link RT_RNaseH_2 PF17919.1 GBG68285.1 - 4.9e-11 42.5 0.0 1.7e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68285.1 - 1.7e-10 40.8 0.1 2.2e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68285.1 - 0.0017 18.6 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68286.1 - 3.7e-36 124.7 0.1 6.4e-36 123.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68286.1 - 5.4e-31 106.6 0.0 1.5e-30 105.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68286.1 - 2.2e-29 101.8 0.0 5e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68286.1 - 6.9e-13 48.5 0.1 1.6e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain ADP_ribosyl_GH PF03747.14 GBG68286.1 - 0.1 12.3 0.1 2.1 8.0 0.2 2.7 3 0 0 3 3 3 0 ADP-ribosylglycohydrolase CDC45 PF02724.14 GBG68286.1 - 2.8 6.1 11.1 3.9 5.6 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein His_Phos_1 PF00300.22 GBG68288.1 - 6.3e-38 130.4 0.3 1.2e-29 103.4 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 GBG68289.1 - 2e-69 233.9 0.0 2.5e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG68289.1 - 1.3e-47 162.3 0.0 1.7e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG68289.1 - 3.8e-06 25.9 0.0 5.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GBG68289.1 - 9.9e-05 21.8 0.0 0.007 15.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GBG68289.1 - 0.0031 17.5 0.0 0.36 10.7 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG68289.1 - 0.022 13.7 0.0 0.43 9.5 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain RT_RNaseH_2 PF17919.1 GBG68290.1 - 8.4e-11 41.8 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BUD22 PF09073.10 GBG68290.1 - 1.3 8.3 16.1 1.7 7.9 16.1 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG68290.1 - 1.5 7.0 11.7 2 6.6 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG68290.1 - 5.8 6.2 16.3 7.3 5.9 16.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG68290.1 - 6.2 4.9 15.7 7.6 4.6 15.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF924 PF06041.11 GBG68291.1 - 6.6e-45 153.4 0.1 2.8e-44 151.4 0.1 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF924 PF06041.11 GBG68292.1 - 5.7e-45 153.6 0.1 2.4e-44 151.6 0.1 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF707 PF05212.12 GBG68293.1 - 1.2e-102 343.2 1.0 3.8e-90 302.2 0.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF707) PapC_C PF13953.6 GBG68294.1 - 0.0006 19.6 41.5 3.6 7.5 0.3 9.3 2 2 10 12 12 12 10 PapC C-terminal domain Toprim_N PF08275.11 GBG68294.1 - 0.0073 16.4 11.6 61 3.7 0.0 7.6 3 2 3 8 8 8 0 DNA primase catalytic core, N-terminal domain RTA1 PF04479.13 GBG68294.1 - 0.04 13.5 12.4 20 4.7 0.0 7.3 2 2 8 10 10 10 0 RTA1 like protein DCR PF14047.6 GBG68294.1 - 0.54 10.5 6.7 31 4.9 0.2 4.9 3 2 4 8 8 8 0 Dppa2/4 conserved region gag-asp_proteas PF13975.6 GBG68296.1 - 4.8e-07 30.3 0.0 1.4e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68296.1 - 8.1e-07 29.6 0.0 2.2e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68296.1 - 1.3e-05 25.0 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG68296.1 - 1.4e-05 24.8 0.1 3e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG68296.1 - 0.0031 17.3 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG68296.1 - 0.0064 16.7 0.3 0.043 14.1 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG68296.1 - 0.052 13.7 0.1 0.2 11.8 0.1 2.0 1 0 0 1 1 1 0 Integrase core domain DUF1104 PF06518.11 GBG68296.1 - 0.12 12.7 1.4 0.3 11.5 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) AP1AR PF15745.5 GBG68296.1 - 0.14 11.7 4.6 0.3 10.7 4.6 1.5 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Use1 PF09753.9 GBG68296.1 - 0.82 9.3 8.5 2 8.1 8.5 1.6 1 0 0 1 1 1 0 Membrane fusion protein Use1 ABC2_membrane_3 PF12698.7 GBG68297.1 - 0.013 14.6 0.6 0.016 14.3 0.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF707 PF05212.12 GBG68298.1 - 1.6e-42 145.8 2.8 2e-42 145.5 2.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF707) DUF4746 PF15928.5 GBG68298.1 - 0.015 14.8 12.9 0.018 14.5 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) LRIF1 PF15741.5 GBG68298.1 - 0.28 9.6 7.1 0.34 9.4 7.1 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Spore_III_AF PF09581.10 GBG68298.1 - 0.29 11.2 13.2 0.43 10.6 13.2 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) AAA_11 PF13086.6 GBG68298.1 - 0.5 10.1 6.3 0.65 9.7 6.3 1.1 1 0 0 1 1 1 0 AAA domain GBP_C PF02841.14 GBG68298.1 - 0.96 8.8 24.1 1.2 8.4 24.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Nucleo_P87 PF07267.11 GBG68298.1 - 1.4 7.7 6.7 1.8 7.4 6.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 GBG68298.1 - 1.8 6.7 8.1 2.1 6.6 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L23eN PF03939.13 GBG68298.1 - 4.7 7.5 7.8 9.7 6.5 7.8 1.5 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain VIR_N PF15912.5 GBG68298.1 - 4.9 6.7 9.5 6.4 6.3 9.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF707 PF05212.12 GBG68299.1 - 9.1e-33 113.8 0.0 1.3e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF707) Wzy_C PF04932.15 GBG68299.1 - 0.034 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase BRI3BP PF14965.6 GBG68299.1 - 0.14 11.6 0.9 0.23 10.9 0.9 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 NOA36 PF06524.12 GBG68301.1 - 0.71 9.1 7.9 0.75 9.1 7.9 1.1 1 0 0 1 1 1 0 NOA36 protein PGA2 PF07543.12 GBG68301.1 - 0.72 9.8 10.3 0.89 9.5 10.3 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2201_N PF13203.6 GBG68301.1 - 1.1 8.8 8.5 1.2 8.7 8.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.14 GBG68301.1 - 1.5 7.1 9.2 1.6 7.0 9.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Prothymosin PF03247.14 GBG68301.1 - 1.8 9.1 18.5 2.2 8.8 18.5 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nucleo_P87 PF07267.11 GBG68301.1 - 7 5.4 10.0 7.9 5.2 10.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Myc_N PF01056.18 GBG68302.1 - 0.001 19.1 0.7 0.001 19.1 0.7 3.8 4 0 0 4 4 4 1 Myc amino-terminal region Pacs-1 PF10254.9 GBG68302.1 - 0.011 14.8 0.4 0.011 14.8 0.4 2.2 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein Velvet PF11754.8 GBG68302.1 - 0.056 13.4 11.1 1.1 9.1 6.7 2.2 2 0 0 2 2 2 0 Velvet factor Apt1 PF10351.9 GBG68302.1 - 0.11 11.4 25.1 0.0061 15.5 16.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain COX14 PF14880.6 GBG68302.1 - 0.14 12.0 0.4 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Peroxin-3 PF04882.12 GBG68302.1 - 0.18 10.7 16.8 0.023 13.7 8.6 2.3 2 0 0 2 2 2 0 Peroxin-3 PRIMA1 PF16101.5 GBG68302.1 - 1.4 9.0 7.9 1.4 9.0 5.6 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Ribosomal_60s PF00428.19 GBG68302.1 - 4.1 8.1 25.5 0.028 15.0 11.7 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein CN_hydrolase PF00795.22 GBG68303.1 - 1e-42 146.3 0.0 1.8e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DBD_Tnp_Mut PF03108.15 GBG68303.1 - 6.3e-14 51.7 0.0 1.6e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 MuDR family transposase MULE PF10551.9 GBG68303.1 - 9.2e-14 51.6 0.0 2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 GBG68303.1 - 1.9e-07 30.6 0.2 4.5e-07 29.4 0.2 1.7 1 0 0 1 1 1 1 SWIM zinc finger zf-C2H2_10 PF16588.5 GBG68303.1 - 0.0017 18.0 6.2 0.006 16.3 6.2 1.9 1 0 0 1 1 1 1 C2H2 zinc-finger Transposase_mut PF00872.18 GBG68303.1 - 0.003 16.5 0.0 0.0059 15.5 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family Flavodoxin_1 PF00258.25 GBG68303.1 - 0.057 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin DUF659 PF04937.15 GBG68304.1 - 3.9e-41 140.4 0.0 6.7e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG68304.1 - 0.053 13.4 4.7 0.2 11.6 4.7 2.1 1 0 0 1 1 1 0 AT hook motif Evr1_Alr PF04777.13 GBG68305.1 - 4.2e-29 101.0 0.6 7.4e-29 100.2 0.6 1.4 1 0 0 1 1 1 1 Erv1 / Alr family SR-25 PF10500.9 GBG68305.1 - 0.023 14.3 8.1 0.039 13.6 8.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3824 PF12868.7 GBG68305.1 - 0.044 14.5 1.2 0.071 13.8 0.5 1.8 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF819 PF05684.12 GBG68306.1 - 1.3e-31 110.0 15.6 2.2e-27 96.1 9.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF819) SseC PF04888.12 GBG68306.1 - 0.71 9.4 7.0 1.2 8.7 7.0 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family RT_RNaseH_2 PF17919.1 GBG68307.1 - 3.2e-36 123.4 0.0 6.1e-36 122.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68307.1 - 1.3e-31 109.0 0.1 3e-31 107.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68307.1 - 9.4e-08 31.8 0.1 1.4e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_21 PF05050.12 GBG68308.1 - 6.5e-13 49.1 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF3791 PF12668.7 GBG68309.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Hexapep PF00132.24 GBG68310.1 - 8.1e-07 28.5 13.0 0.012 15.4 0.5 4.7 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) DUF3797 PF12677.7 GBG68310.1 - 0.018 14.9 0.1 0.1 12.5 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) FERM_f0 PF16511.5 GBG68310.1 - 0.31 11.4 7.6 20 5.6 0.1 4.0 1 1 2 3 3 3 0 N-terminal or F0 domain of Talin-head FERM IMCp PF12314.8 GBG68310.1 - 5.5 7.4 16.8 2.5 8.5 11.1 2.6 1 1 2 3 3 3 0 Inner membrane complex protein Hexapep PF00132.24 GBG68311.1 - 1.8e-09 36.9 20.3 0.016 14.9 0.4 6.2 3 3 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) DUF3797 PF12677.7 GBG68311.1 - 0.012 15.5 1.6 0.089 12.7 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) DUF963 PF06131.11 GBG68311.1 - 0.031 13.7 49.2 1.5 8.3 4.7 6.6 2 2 2 5 5 5 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) IMCp PF12314.8 GBG68311.1 - 0.28 11.5 22.6 11 6.3 2.1 3.5 1 1 3 4 4 4 0 Inner membrane complex protein Myb_DNA-bind_4 PF13837.6 GBG68312.1 - 1.3e-09 38.2 0.8 4.1e-09 36.7 0.3 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG68312.1 - 0.16 12.3 0.2 0.33 11.3 0.2 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG68312.1 - 0.28 11.3 0.8 0.66 10.1 0.8 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG68314.1 - 4.7e-11 42.9 3.1 4.8e-11 42.9 1.0 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG68314.1 - 0.0066 16.7 0.2 0.018 15.4 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like RCR PF12273.8 GBG68314.1 - 0.19 12.4 0.8 0.57 10.8 0.0 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DDE_Tnp_4 PF13359.6 GBG68316.1 - 7.6e-33 113.4 0.0 9.7e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68316.1 - 4.2e-16 59.2 0.0 5.8e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68316.1 - 1.5e-06 28.1 0.2 0.0044 16.7 0.0 2.3 2 1 0 2 2 2 2 Transposase DDE domain PPR_2 PF13041.6 GBG68317.1 - 6.3e-69 228.0 0.0 4.9e-12 45.9 0.0 11.5 4 1 7 11 11 11 10 PPR repeat family PPR PF01535.20 GBG68317.1 - 6.9e-68 220.3 2.9 1.6e-06 27.9 0.0 13.1 13 0 0 13 13 13 10 PPR repeat PPR_3 PF13812.6 GBG68317.1 - 2.3e-63 210.1 0.0 6.9e-14 51.7 0.0 8.3 6 2 2 8 8 8 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG68317.1 - 1.5e-54 181.4 0.0 3.9e-07 29.6 0.0 9.8 11 0 0 11 11 11 8 PPR repeat PPR_long PF17177.4 GBG68317.1 - 2e-29 102.5 0.0 1.1e-12 47.8 0.0 4.8 1 1 4 5 5 5 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG68317.1 - 7.4e-07 29.6 0.1 0.19 12.3 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG68317.1 - 2.9e-06 27.6 4.9 33 5.6 0.0 8.6 6 4 3 9 9 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG68317.1 - 0.00092 19.4 0.0 13 6.1 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GBG68317.1 - 0.0043 16.3 0.1 3.1 6.9 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat PYRIN PF02758.16 GBG68317.1 - 0.12 12.5 0.2 22 5.3 0.0 4.5 7 0 0 7 7 7 0 PAAD/DAPIN/Pyrin domain ECSIT PF06239.11 GBG68317.1 - 0.18 10.9 0.1 1.2 8.2 0.1 2.3 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Myc_N PF01056.18 GBG68317.1 - 2.5 7.9 4.7 5.2 6.9 4.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region PPP4R2 PF09184.11 GBG68317.1 - 3.8 7.0 9.3 6.2 6.3 9.3 1.2 1 0 0 1 1 1 0 PPP4R2 DDE_Tnp_4 PF13359.6 GBG68319.1 - 2.2e-21 76.2 0.0 3.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68319.1 - 1.9e-08 34.1 0.0 3.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68319.1 - 0.031 13.9 0.1 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 Transposase DDE domain bZIP_1 PF00170.21 GBG68320.1 - 1.1e-12 47.8 15.6 2.6e-12 46.6 15.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG68320.1 - 1.7e-10 40.8 17.7 4.7e-10 39.4 17.7 1.8 1 0 0 1 1 1 1 Basic region leucine zipper BAF1_ABF1 PF04684.13 GBG68320.1 - 0.0019 17.4 0.7 0.0019 17.4 0.7 2.2 3 0 0 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor bZIP_Maf PF03131.17 GBG68320.1 - 0.01 16.3 11.8 0.01 16.3 11.8 4.3 4 1 0 4 4 4 0 bZIP Maf transcription factor DUF2052 PF09747.9 GBG68320.1 - 0.026 14.7 0.0 0.026 14.7 0.0 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) betaPIX_CC PF16523.5 GBG68320.1 - 0.037 13.9 3.6 0.1 12.4 3.6 1.7 1 0 0 1 1 1 0 betaPIX coiled coil bZIP_1 PF00170.21 GBG68321.1 - 1.1e-12 47.9 14.9 2.5e-12 46.7 14.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG68321.1 - 5.2e-11 42.4 16.0 1.5e-10 41.0 16.0 1.8 1 0 0 1 1 1 1 Basic region leucine zipper BAF1_ABF1 PF04684.13 GBG68321.1 - 0.0019 17.4 0.7 0.0019 17.4 0.7 2.2 3 0 0 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor bZIP_Maf PF03131.17 GBG68321.1 - 0.018 15.6 12.4 0.018 15.6 12.4 4.3 4 1 0 4 4 4 0 bZIP Maf transcription factor DUF2052 PF09747.9 GBG68321.1 - 0.026 14.7 0.0 0.026 14.7 0.0 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) betaPIX_CC PF16523.5 GBG68321.1 - 0.046 13.6 2.8 0.13 12.1 2.8 1.7 1 0 0 1 1 1 0 betaPIX coiled coil HRI1 PF16815.5 GBG68322.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein HRI1 gag-asp_proteas PF13975.6 GBG68323.1 - 0.0018 18.8 0.1 0.0053 17.3 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68323.1 - 0.0057 17.3 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG68323.1 - 0.015 15.5 0.3 0.045 14.0 0.2 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 GBG68323.1 - 0.016 15.5 0.1 0.038 14.3 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4763 PF15960.5 GBG68323.1 - 0.35 10.1 1.8 1.2 8.4 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) DUF2057 PF09829.9 GBG68324.1 - 0.078 13.1 0.2 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) RVT_1 PF00078.27 GBG68325.1 - 1.3e-24 86.9 0.1 2.1e-24 86.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68325.1 - 2.2e-12 46.9 0.0 4.2e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG68325.1 - 4.6e-06 26.5 2.2 8.5e-06 25.6 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH PF17917.1 GBG68325.1 - 7.7e-05 22.9 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_2 PF13696.6 GBG68325.1 - 0.017 14.9 3.9 0.017 14.9 3.9 2.1 2 0 0 2 2 2 0 Zinc knuckle Vfa1 PF08432.10 GBG68325.1 - 0.59 10.4 4.9 1.6 9.0 4.9 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mito_fiss_reg PF05308.11 GBG68326.1 - 2.2 8.3 9.2 6.9 6.7 3.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Ribosomal_L12 PF00542.19 GBG68327.1 - 3.5e-23 81.7 11.3 2.4e-22 79.1 7.6 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 GBG68327.1 - 3.7e-10 39.3 11.9 3.7e-10 39.3 11.9 4.3 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain Stm1_N PF09598.10 GBG68330.1 - 0.036 14.9 9.2 0.036 14.9 9.2 5.3 1 1 1 2 2 2 0 Stm1 MH1 PF03165.16 GBG68331.1 - 0.05 13.8 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 MH1 domain Pkinase_Tyr PF07714.17 GBG68332.1 - 1.3e-07 31.1 0.0 1.4e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG68332.1 - 7.8e-06 25.4 0.0 7.8e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 GBG68333.1 - 0.00046 19.6 0.0 0.00073 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG68333.1 - 0.0006 19.2 0.0 0.00095 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase alpha-hel2 PF14456.6 GBG68333.1 - 1.1 8.5 4.2 2 7.6 4.2 1.4 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF1682 PF07946.14 GBG68333.1 - 1.4 8.0 4.1 2.2 7.4 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DNA_pol_phi PF04931.13 GBG68333.1 - 4.3 5.3 5.9 5.8 4.9 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi SOAR PF16533.5 GBG68334.1 - 0.0086 16.0 3.1 0.0086 16.0 3.1 2.5 2 1 0 2 2 2 1 STIM1 Orai1-activating region Filament PF00038.21 GBG68334.1 - 0.011 15.3 16.3 0.38 10.3 2.8 2.4 2 0 0 2 2 2 0 Intermediate filament protein DUF2201 PF09967.9 GBG68334.1 - 0.054 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 VWA-like domain (DUF2201) LPP PF04728.13 GBG68334.1 - 0.22 12.0 2.8 3.3 8.2 0.0 3.3 3 1 0 3 3 3 0 Lipoprotein leucine-zipper TolA_bind_tri PF16331.5 GBG68334.1 - 0.23 11.5 12.3 0.11 12.6 4.4 3.6 2 2 1 3 3 3 0 TolA binding protein trimerisation MbeD_MobD PF04899.12 GBG68334.1 - 0.46 10.6 9.5 0.69 10.1 2.2 3.1 2 1 1 3 3 3 0 MbeD/MobD like DUF4407 PF14362.6 GBG68334.1 - 1.1 8.5 7.6 1.6 8.0 7.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 GBG68334.1 - 2 7.2 16.7 3.7 6.3 4.9 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 GBG68334.1 - 2.6 8.6 15.6 6.2 7.4 6.1 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 GBG68334.1 - 3.2 8.4 10.9 1.4 9.6 0.5 3.4 1 1 3 4 4 4 0 Initiation control protein YabA DUF2282 PF10048.9 GBG68336.1 - 0.36 10.9 4.2 0.23 11.5 1.1 2.4 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2282) IATP PF04568.12 GBG68337.1 - 0.27 11.7 2.3 0.36 11.3 0.2 2.3 2 1 1 3 3 3 0 Mitochondrial ATPase inhibitor, IATP DUF2294 PF10057.9 GBG68338.1 - 0.05 13.7 0.1 0.076 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) ABC_trans_aux PF03886.13 GBG68338.1 - 0.11 12.0 1.1 0.12 12.0 0.1 1.5 2 0 0 2 2 2 0 ABC-type transport auxiliary lipoprotein component Integrase_H2C2 PF17921.1 GBG68339.1 - 3e-19 68.9 0.2 6e-19 67.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68339.1 - 2.6e-09 37.3 0.0 8.8e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG68339.1 - 9.3e-05 22.2 0.0 0.0003 20.6 0.0 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Retrotrans_gag PF03732.17 GBG68339.1 - 0.00093 19.4 0.1 0.0099 16.1 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein WTX PF09422.10 GBG68339.1 - 0.018 14.1 2.2 0.04 13.0 2.2 1.4 1 0 0 1 1 1 0 WTX protein zf-H2C2 PF09337.10 GBG68339.1 - 0.043 14.0 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Proteasom_PSMB PF10508.9 GBG68340.1 - 3e-24 85.4 0.0 7.2e-24 84.2 0.0 1.5 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit Cytomega_UL84 PF06284.11 GBG68340.1 - 0.087 11.3 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RVT_1 PF00078.27 GBG68341.1 - 1.1e-23 84.0 0.0 2e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG68341.1 - 3.4e-06 27.6 0.0 9.3e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68341.1 - 6.8e-06 25.9 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG68341.1 - 0.0007 20.1 0.0 0.0024 18.4 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TolA_bind_tri PF16331.5 GBG68341.1 - 0.16 12.1 7.9 0.084 13.0 5.1 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation WTX PF09422.10 GBG68341.1 - 0.34 9.9 9.7 0.017 14.2 1.2 2.2 2 0 0 2 2 2 0 WTX protein CDC27 PF09507.10 GBG68342.1 - 0.32 10.3 15.7 0.35 10.2 15.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PIEZO PF15917.5 GBG68342.1 - 0.39 10.2 8.8 0.46 9.9 8.8 1.1 1 0 0 1 1 1 0 Piezo PA26 PF04636.13 GBG68342.1 - 4.9 6.0 7.2 5.4 5.8 7.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) zf-CCHC PF00098.23 GBG68343.1 - 7.7e-08 32.1 2.4 1.2e-07 31.5 2.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4778 PF16008.5 GBG68343.1 - 0.05 13.7 9.7 0.074 13.1 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) zf-CCHC_4 PF14392.6 GBG68343.1 - 0.091 12.5 1.0 0.16 11.7 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle EXS PF03124.14 GBG68344.1 - 1.4e-90 304.0 27.0 1.9e-90 303.6 27.0 1.2 1 0 0 1 1 1 1 EXS family Integrase_H2C2 PF17921.1 GBG68344.1 - 1.4e-16 60.3 0.7 1.4e-16 60.3 0.7 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG68344.1 - 4e-14 52.8 1.3 8.4e-14 51.7 1.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68344.1 - 2.3e-12 47.1 0.0 5.4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG68344.1 - 3.2e-06 27.1 0.5 6.4e-06 26.1 0.5 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG68344.1 - 0.0091 16.2 0.0 0.033 14.4 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF913 PF06025.12 GBG68344.1 - 0.02 13.9 2.7 0.047 12.7 2.7 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Yip1 PF04893.17 GBG68344.1 - 0.06 13.1 7.8 0.14 11.8 7.8 1.6 1 0 0 1 1 1 0 Yip1 domain Presenilin PF01080.17 GBG68344.1 - 2.5 6.8 16.9 1.7 7.3 11.1 2.3 2 0 0 2 2 2 0 Presenilin Beta_helix PF13229.6 GBG68346.1 - 4.6e-08 33.1 1.9 4.3e-05 23.4 0.0 2.4 1 1 1 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG68346.1 - 2.8e-05 24.3 24.1 0.75 10.4 0.1 6.1 6 0 0 6 6 6 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NosD PF05048.13 GBG68346.1 - 0.053 12.8 0.0 0.42 9.8 0.0 1.9 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 GBG68347.1 - 0.058 13.9 19.4 0.19 12.3 0.1 4.1 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chlam_PMP PF02415.17 GBG68348.1 - 0.00025 21.3 13.8 0.13 12.8 0.0 5.9 5 0 0 5 5 5 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RVP_2 PF08284.11 GBG68348.1 - 0.0062 16.3 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG68348.1 - 0.043 14.1 1.7 0.1 12.9 0.4 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein SlyX PF04102.12 GBG68348.1 - 0.77 10.4 4.4 0.54 10.9 0.6 2.5 2 0 0 2 2 2 0 SlyX Beta_helix PF13229.6 GBG68349.1 - 2.1e-05 24.5 0.0 0.00041 20.2 0.0 2.1 1 1 1 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG68352.1 - 7e-08 32.5 4.8 0.071 13.6 0.1 5.0 4 0 0 4 4 4 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chlam_PMP PF02415.17 GBG68353.1 - 6.3e-08 32.6 9.4 0.077 13.5 0.2 5.3 5 0 0 5 5 5 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 GBG68353.1 - 9.7e-05 22.3 0.0 0.029 14.2 0.1 2.2 1 1 1 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG68354.1 - 6.2e-08 32.7 9.4 0.077 13.5 0.2 5.3 5 0 0 5 5 5 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 GBG68354.1 - 9.7e-05 22.3 0.0 0.029 14.2 0.1 2.2 1 1 1 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG68355.1 - 4e-07 30.1 13.5 0.063 13.8 0.1 5.6 5 1 0 5 5 5 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 GBG68355.1 - 3e-05 23.9 0.0 0.00036 20.4 0.0 2.2 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG68358.1 - 1.6e-07 31.3 11.8 0.063 13.8 0.1 5.6 5 0 0 5 5 5 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 GBG68358.1 - 4.2e-07 30.0 0.5 0.00062 19.6 0.1 2.2 1 1 2 3 3 3 3 Right handed beta helix region RVT_1 PF00078.27 GBG68359.1 - 7.5e-31 107.4 0.1 5.7e-22 78.3 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68359.1 - 1.8e-30 104.9 0.0 4.5e-16 58.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68359.1 - 5.2e-29 100.6 0.0 1e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68360.1 - 1.7e-28 98.6 0.0 7.2e-27 93.4 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68360.1 - 7.9e-25 87.2 0.0 2.8e-24 85.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG68360.1 - 4.1 5.5 31.5 7.6 4.6 31.5 1.3 1 0 0 1 1 1 0 Nop14-like family PDZ_3 PF17815.1 GBG68361.1 - 6.6e-34 116.8 1.8 1.5e-23 83.3 0.3 2.3 1 1 1 2 2 2 2 PDZ domain Trypsin_2 PF13365.6 GBG68361.1 - 1.4e-07 32.5 0.5 0.00015 22.7 0.1 2.9 2 1 1 3 3 3 2 Trypsin-like peptidase domain Trypsin PF00089.26 GBG68361.1 - 4e-06 26.8 0.1 0.00016 21.6 0.1 2.6 2 1 1 3 3 3 1 Trypsin PDZ_2 PF13180.6 GBG68361.1 - 7.5e-06 26.2 0.0 0.00017 21.8 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GBG68361.1 - 1.9e-05 24.4 0.1 0.043 13.7 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 GBG68361.1 - 0.0029 17.9 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 GBG68361.1 - 0.0064 15.2 0.2 0.009 14.7 0.2 1.1 1 0 0 1 1 1 1 Peptidase S46 Peptidase_S7 PF00949.21 GBG68361.1 - 0.09 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease ParD_antitoxin PF03693.14 GBG68363.1 - 0.076 13.4 0.0 21 5.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Mito_fiss_reg PF05308.11 GBG68364.1 - 2.9 7.9 16.9 0.35 10.9 6.1 2.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Leu_leader PF08054.11 GBG68365.1 - 0.02 14.5 8.0 2.4 7.8 0.2 3.5 3 0 0 3 3 3 0 Leucine operon leader peptide Integrase_H2C2 PF17921.1 GBG68366.1 - 9.6e-18 64.0 0.1 9.6e-18 64.0 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG68366.1 - 0.0029 17.8 0.0 0.012 15.8 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG68366.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG68366.1 - 0.026 14.7 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG68367.1 - 4.6e-18 65.1 0.1 8.2e-18 64.3 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68367.1 - 0.0023 18.1 0.0 0.01 16.0 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG68367.1 - 0.0084 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG68367.1 - 0.029 14.6 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Myc_N PF01056.18 GBG68368.1 - 0.38 10.6 5.2 0.13 12.1 1.5 1.9 2 0 0 2 2 2 0 Myc amino-terminal region rve PF00665.26 GBG68369.1 - 6.7e-15 55.3 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Mid2 PF04478.12 GBG68369.1 - 1.6e-05 24.8 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor RVT_1 PF00078.27 GBG68369.1 - 0.00032 20.3 0.1 0.0006 19.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2385 PF09539.10 GBG68369.1 - 0.15 12.6 0.1 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) NARP1 PF12569.8 GBG68370.1 - 4.1 6.2 8.3 6.8 5.5 8.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DLH PF01738.18 GBG68371.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Apt1 PF10351.9 GBG68372.1 - 1.3 7.8 5.3 1.9 7.3 5.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 GBG68372.1 - 7.9 4.9 8.0 12 4.3 8.0 1.1 1 0 0 1 1 1 0 Macoilin family Cupin_3 PF05899.12 GBG68373.1 - 1.2e-30 105.0 1.1 2e-30 104.3 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 GBG68373.1 - 3.5e-05 23.4 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 GBG68373.1 - 6.4e-05 22.7 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.22 GBG68373.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 GBG68373.1 - 0.003 17.3 0.1 0.0086 15.8 0.0 1.7 2 0 0 2 2 2 1 Cupin zf-CCHC PF00098.23 GBG68374.1 - 8.2e-06 25.7 2.4 1.7e-05 24.7 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG68375.1 - 0.0078 16.0 1.7 0.017 14.9 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG68375.1 - 0.026 14.6 1.0 0.06 13.4 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.22 GBG68376.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 GBG68376.1 - 0.095 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 GBG68377.1 - 8.9e-26 91.1 0.0 1.1e-25 90.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Exo5 PF09810.9 GBG68378.1 - 2.3e-61 208.3 8.7 3.6e-33 115.6 0.1 3.1 1 1 2 3 3 3 3 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 GBG68378.1 - 3.5e-11 43.5 0.1 5.5e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Dapper PF15268.6 GBG68379.1 - 0.032 13.1 7.3 0.033 13.1 7.3 1.0 1 0 0 1 1 1 0 Dapper Vfa1 PF08432.10 GBG68379.1 - 0.1 12.9 19.1 0.12 12.6 19.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FB_lectin PF07367.11 GBG68379.1 - 0.14 12.1 2.9 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Fungal fruit body lectin Exonuc_VII_L PF02601.15 GBG68379.1 - 0.61 9.6 6.6 0.67 9.5 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ESM4 PF15952.5 GBG68379.1 - 1.1 9.6 7.8 1.3 9.4 7.8 1.2 1 0 0 1 1 1 0 Enhancer of split M4 family FAM60A PF15396.6 GBG68379.1 - 1.3 9.0 8.5 1.4 8.9 8.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Histidinol_dh PF00815.20 GBG68379.1 - 1.4 7.8 4.5 2.4 7.1 4.5 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase VPS38 PF17649.1 GBG68379.1 - 1.8 7.3 9.3 2.4 7.0 9.3 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Atg14 PF10186.9 GBG68379.1 - 1.8 7.6 11.2 2 7.4 11.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PIEZO PF15917.5 GBG68379.1 - 1.9 7.9 13.1 2.2 7.7 13.1 1.1 1 0 0 1 1 1 0 Piezo DUF2151 PF10221.9 GBG68379.1 - 2 6.9 15.6 2.4 6.7 15.6 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Tho2 PF11262.8 GBG68379.1 - 2.1 7.5 10.7 3 7.0 10.7 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PA26 PF04636.13 GBG68379.1 - 3.6 6.4 8.7 3.6 6.4 8.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Sec62 PF03839.16 GBG68379.1 - 4.8 6.6 11.2 5.4 6.5 11.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Macoilin PF09726.9 GBG68379.1 - 5.1 5.5 14.7 4.7 5.6 14.7 1.1 1 0 0 1 1 1 0 Macoilin family FemAB PF02388.16 GBG68379.1 - 5.9 5.7 11.6 7.5 5.3 11.6 1.1 1 0 0 1 1 1 0 FemAB family BUD22 PF09073.10 GBG68379.1 - 7.6 5.8 26.6 8.6 5.6 26.6 1.1 1 0 0 1 1 1 0 BUD22 DDHD PF02862.17 GBG68379.1 - 8 6.6 6.1 8.8 6.4 6.1 1.1 1 0 0 1 1 1 0 DDHD domain DUF4481 PF14800.6 GBG68379.1 - 9.3 5.6 7.2 11 5.4 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) DUF1798 PF08807.10 GBG68380.1 - 0.021 14.9 1.2 0.058 13.5 1.2 1.7 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) RasGEF_N_2 PF14663.6 GBG68380.1 - 0.047 14.1 0.1 0.13 12.6 0.1 1.8 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GARP PF16731.5 GBG68380.1 - 0.049 13.3 7.4 0.11 12.1 7.4 1.6 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Cupin_4 PF08007.12 GBG68380.1 - 1.6 8.1 5.6 14 5.0 2.0 2.4 2 1 0 2 2 2 0 Cupin superfamily protein Rx_N PF18052.1 GBG68380.1 - 2.9 8.2 7.8 9.7 6.6 6.0 2.6 2 1 0 2 2 2 0 Rx N-terminal domain Borrelia_P83 PF05262.11 GBG68380.1 - 3.5 6.0 11.3 3.9 5.9 11.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein bZIP_1 PF00170.21 GBG68382.1 - 1e-12 48.0 16.9 1.4e-12 47.5 16.0 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GBG68382.1 - 3.2e-09 36.7 16.1 3.2e-09 36.7 16.1 3.0 3 1 1 4 4 4 1 Basic region leucine zipper Methyltransf_34 PF11312.8 GBG68382.1 - 0.32 10.2 2.7 0.77 8.9 2.7 1.7 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase TSC22 PF01166.18 GBG68382.1 - 2.5 8.5 5.7 0.46 10.8 1.6 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family zf-CCHC PF00098.23 GBG68386.1 - 0.016 15.2 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG68387.1 - 1.7e-06 28.3 4.0 1.7e-06 28.3 4.0 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG68387.1 - 0.0015 18.6 2.0 0.0015 18.6 2.0 2.5 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG68387.1 - 0.0029 17.8 1.4 0.0054 17.0 1.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG68387.1 - 0.052 13.7 1.3 0.11 12.7 0.7 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG68387.1 - 0.082 13.2 4.8 0.1 13.0 0.9 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GRP PF07172.11 GBG68387.1 - 7.6 7.3 0.0 7.6 7.3 0.0 4.1 4 0 0 4 4 4 0 Glycine rich protein family DDE_Tnp_4 PF13359.6 GBG68388.1 - 1.1e-31 109.7 0.0 6.7e-31 107.1 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68388.1 - 6.1e-19 68.4 0.0 9.9e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68388.1 - 2.3e-06 27.4 0.4 0.027 14.1 0.0 2.5 2 0 0 2 2 2 2 Transposase DDE domain ROQ_II PF18386.1 GBG68389.1 - 0.031 14.1 2.2 0.33 10.8 0.2 2.7 1 1 1 2 2 2 0 Roquin II domain Nop14 PF04147.12 GBG68390.1 - 0.11 10.7 6.8 0.15 10.2 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG68390.1 - 0.74 9.2 9.4 0.95 8.8 9.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG68390.1 - 1.6 6.9 5.9 2.2 6.5 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DNApol_Exo PF18136.1 GBG68391.1 - 0.013 14.6 3.2 0.02 14.1 3.2 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Mo-co_dimer PF03404.16 GBG68391.1 - 0.021 14.8 0.2 0.036 14.1 0.2 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain DUF4407 PF14362.6 GBG68391.1 - 0.029 13.7 12.0 0.044 13.1 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MEDS PF14417.6 GBG68391.1 - 0.14 11.9 0.7 0.21 11.4 0.7 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain MDM10 PF12519.8 GBG68391.1 - 0.43 9.4 4.8 0.6 8.9 4.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Atg14 PF10186.9 GBG68391.1 - 0.81 8.7 7.8 1 8.4 7.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4522 PF15022.6 GBG68391.1 - 1.9 8.7 6.2 2 8.7 4.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) Fib_alpha PF08702.10 GBG68391.1 - 2.2 8.5 6.8 0.22 11.7 0.7 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 GBG68391.1 - 2.4 7.4 12.8 3.2 7.0 12.8 1.1 1 0 0 1 1 1 0 FAM76 protein AAA_13 PF13166.6 GBG68391.1 - 2.8 6.5 13.5 3.6 6.1 13.5 1.0 1 0 0 1 1 1 0 AAA domain HSP70 PF00012.20 GBG68391.1 - 3.4 5.7 13.5 4.3 5.4 13.5 1.2 1 0 0 1 1 1 0 Hsp70 protein Casc1_N PF15927.5 GBG68391.1 - 6.9 6.3 31.9 0.18 11.5 20.4 2.2 1 1 1 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Nop14 PF04147.12 GBG68392.1 - 2.5 6.2 8.2 2.7 6.1 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_79n PF03662.14 GBG68394.1 - 6.9e-89 297.9 0.8 7.2e-64 215.7 0.0 2.8 2 1 0 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain G-patch_2 PF12656.7 GBG68395.1 - 4.3e-17 61.9 0.1 1.5e-16 60.2 0.1 2.0 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 GBG68395.1 - 0.0031 17.4 0.1 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 KOW motif DUF1685 PF07939.11 GBG68396.1 - 0.0017 18.0 0.5 0.58 10.0 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1685) Mito_fiss_reg PF05308.11 GBG68396.1 - 7.7 6.5 11.1 3 7.9 3.4 2.9 3 0 0 3 3 3 0 Mitochondrial fission regulator p450 PF00067.22 GBG68397.1 - 4.3e-57 193.9 0.0 3.9e-36 124.8 0.0 2.4 2 0 0 2 2 2 2 Cytochrome P450 RVT_1 PF00078.27 GBG68398.1 - 1.4e-30 106.5 0.0 2.1e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.22 GBG68399.1 - 1.1e-83 281.6 0.0 2.3e-60 204.7 0.0 3.3 3 1 0 3 3 3 2 Cytochrome P450 RT_RNaseH_2 PF17919.1 GBG68400.1 - 1.7e-27 95.4 0.0 4.4e-27 94.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68400.1 - 6e-27 94.6 0.0 1.1e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68400.1 - 4.2e-26 91.3 0.0 9.9e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68400.1 - 5.4e-19 68.1 1.0 1.5e-18 66.7 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG68400.1 - 1.8e-11 44.2 0.0 5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain TMF_TATA_bd PF12325.8 GBG68400.1 - 0.034 14.4 0.5 0.034 14.4 0.5 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding zf-H2C2 PF09337.10 GBG68400.1 - 0.076 13.2 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG68400.1 - 0.11 12.8 5.6 21 5.5 0.1 4.4 4 0 0 4 4 4 0 Retrotransposon gag protein Tup_N PF08581.10 GBG68400.1 - 0.43 10.9 3.4 0.33 11.3 0.7 2.2 2 0 0 2 2 2 0 Tup N-terminal CLZ PF16526.5 GBG68400.1 - 0.85 10.0 6.8 1.1 9.7 1.9 3.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pkinase_Tyr PF07714.17 GBG68401.1 - 2.5e-37 128.6 0.0 7.9e-35 120.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG68401.1 - 1.6e-36 126.0 0.0 6.7e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG68401.1 - 0.00064 19.7 0.1 0.03 14.2 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family NHL PF01436.21 GBG68401.1 - 0.0026 17.7 0.3 0.0074 16.3 0.1 1.9 2 0 0 2 2 2 1 NHL repeat Vir_act_alpha_C PF10400.9 GBG68402.1 - 0.023 15.3 0.2 0.066 13.9 0.0 1.7 1 1 1 2 2 2 0 Virulence activator alpha C-term CitMHS PF03600.16 GBG68404.1 - 0.23 10.6 19.9 0.43 9.7 19.9 1.4 1 0 0 1 1 1 0 Citrate transporter Ceramidase PF05875.12 GBG68404.1 - 4.6 6.6 11.9 8.6 5.7 11.9 1.4 1 0 0 1 1 1 0 Ceramidase zf-RING_2 PF13639.6 GBG68407.1 - 2.4e-09 37.4 11.0 4.9e-09 36.4 11.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG68407.1 - 2.8e-09 36.8 10.0 6.6e-09 35.7 10.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GBG68407.1 - 5.4e-08 32.6 11.9 1.1e-07 31.6 11.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG68407.1 - 1.3e-07 31.3 10.9 2.6e-07 30.4 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG68407.1 - 1.8e-06 27.8 12.8 3.5e-06 26.9 12.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GBG68407.1 - 2.1e-06 27.4 11.5 4.7e-06 26.3 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG68407.1 - 3.3e-05 24.0 11.0 8.3e-05 22.7 11.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GBG68407.1 - 0.00093 19.0 14.1 0.0028 17.5 8.4 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GBG68407.1 - 0.0015 18.8 9.9 0.009 16.3 10.0 2.3 1 1 1 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 GBG68407.1 - 0.0044 17.2 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-ANAPC11 PF12861.7 GBG68407.1 - 0.0063 16.5 6.3 0.012 15.6 6.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 GBG68407.1 - 0.051 13.9 5.2 1.1 9.6 1.8 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 GBG68407.1 - 0.056 13.2 10.7 0.12 12.2 10.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 GBG68407.1 - 0.092 12.5 5.8 0.2 11.4 5.8 1.6 1 0 0 1 1 1 0 RING-like zinc finger Tup_N PF08581.10 GBG68407.1 - 0.15 12.4 3.9 0.56 10.6 0.4 2.8 2 0 0 2 2 2 0 Tup N-terminal zf-Nse PF11789.8 GBG68407.1 - 0.18 11.6 9.3 0.44 10.4 9.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Med10 PF09748.9 GBG68407.1 - 0.66 9.9 3.4 28 4.7 0.3 3.2 3 1 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex GAGA PF09237.11 GBG68407.1 - 1.3 8.8 6.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 GAGA factor DZR PF12773.7 GBG68407.1 - 7.8 6.6 11.9 32 4.7 11.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon Cir_N PF10197.9 GBG68408.1 - 8e-13 48.3 7.1 8e-13 48.3 7.1 9.4 11 1 0 11 11 11 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 GBG68408.1 - 7.1e-11 42.9 0.2 7.1e-11 42.9 0.2 5.6 5 2 0 5 5 5 1 Pre-mRNA splicing factor KH_dom-like PF14714.6 GBG68409.1 - 3.2e-20 72.2 0.0 5.5e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal MMR_HSR1 PF01926.23 GBG68411.1 - 6e-36 123.0 0.0 6e-19 68.2 0.0 3.7 3 0 0 3 3 3 3 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG68411.1 - 2.2e-13 50.0 0.0 1.7e-08 34.1 0.0 3.0 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 GBG68411.1 - 1.6e-11 44.1 0.0 0.00056 19.5 0.0 4.4 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GBG68411.1 - 1.9e-06 27.9 0.0 0.37 10.7 0.0 4.3 4 0 0 4 4 4 2 RsgA GTPase Dynamin_N PF00350.23 GBG68411.1 - 1.8e-05 24.9 9.9 0.047 13.7 0.0 5.3 5 1 0 5 5 5 2 Dynamin family AIG1 PF04548.16 GBG68411.1 - 0.0007 19.0 0.0 0.47 9.7 0.0 2.8 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 GBG68411.1 - 0.0023 18.2 0.0 2 8.7 0.0 3.7 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GBG68411.1 - 0.018 14.5 4.4 1.3 8.4 0.0 3.1 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 GBG68411.1 - 0.021 15.1 1.4 8.3 6.7 0.0 4.1 4 1 0 4 4 4 0 AAA domain ABC_tran PF00005.27 GBG68411.1 - 0.074 13.6 2.8 2.3 8.7 0.0 3.7 2 1 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 GBG68412.1 - 1.5e-34 118.5 0.0 1.6e-17 63.6 0.0 3.7 3 0 0 3 3 3 3 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG68412.1 - 9.6e-11 41.4 0.0 7.8e-06 25.5 0.0 3.0 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 GBG68412.1 - 3.1e-06 26.9 0.0 0.0041 16.7 0.0 4.0 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GBG68412.1 - 5.7e-06 26.5 7.9 0.038 14.1 0.0 5.1 5 0 0 5 5 5 2 Dynamin family RsgA_GTPase PF03193.16 GBG68412.1 - 1.7e-05 24.8 0.0 0.37 10.7 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase AIG1 PF04548.16 GBG68412.1 - 0.00082 18.8 0.0 0.47 9.7 0.0 2.7 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 GBG68412.1 - 0.0024 18.1 0.0 1.9 8.7 0.0 3.6 3 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GBG68412.1 - 0.038 14.3 1.7 8.2 6.7 0.0 4.1 4 1 0 4 4 4 0 AAA domain ABC_tran PF00005.27 GBG68412.1 - 0.13 12.8 3.6 2.4 8.7 0.0 3.7 2 1 0 2 2 2 0 ABC transporter SKI PF01202.22 GBG68413.1 - 1.7e-32 112.7 0.0 2.9e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 GBG68413.1 - 5.7e-08 33.4 0.0 2e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 GBG68413.1 - 4.6e-06 26.9 0.0 0.00013 22.1 0.0 2.2 1 1 1 2 2 2 1 Cytidylate kinase-like family AAA_33 PF13671.6 GBG68413.1 - 5.3e-05 23.4 0.0 0.00023 21.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain CoaE PF01121.20 GBG68413.1 - 0.039 13.6 0.3 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_29 PF13555.6 GBG68413.1 - 0.073 12.8 0.4 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain dNK PF01712.19 GBG68413.1 - 0.11 12.3 0.0 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase Yip1 PF04893.17 GBG68414.1 - 0.0076 16.0 16.2 0.015 15.0 16.2 1.6 1 1 0 1 1 1 1 Yip1 domain CDC45 PF02724.14 GBG68415.1 - 6.9e-06 24.6 12.4 8.8e-06 24.3 12.4 1.1 1 0 0 1 1 1 1 CDC45-like protein PTPRCAP PF15713.5 GBG68415.1 - 0.0089 16.3 18.3 0.0089 16.3 18.3 1.8 2 0 0 2 2 1 1 Protein tyrosine phosphatase receptor type C-associated BSP_II PF05432.11 GBG68415.1 - 0.034 13.9 26.8 0.051 13.3 26.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SDA1 PF05285.12 GBG68415.1 - 0.038 13.4 21.8 0.054 12.9 21.8 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG68415.1 - 0.063 11.9 21.8 0.086 11.4 21.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.15 GBG68415.1 - 0.064 12.0 2.0 0.074 11.8 2.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.11 GBG68415.1 - 0.12 11.8 2.7 0.15 11.4 2.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein V_ATPase_I PF01496.19 GBG68415.1 - 0.13 10.2 0.3 0.16 9.8 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LAP1C PF05609.12 GBG68415.1 - 0.24 10.5 11.8 0.31 10.1 11.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RR_TM4-6 PF06459.12 GBG68415.1 - 0.26 11.1 11.8 0.51 10.1 11.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sporozoite_P67 PF05642.11 GBG68415.1 - 0.71 7.9 14.3 1 7.4 14.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4614 PF15391.6 GBG68415.1 - 1.5 8.8 10.4 2.7 7.9 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PI3K_1B_p101 PF10486.9 GBG68415.1 - 1.9 6.2 7.6 2.5 5.8 7.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Mpp10 PF04006.12 GBG68415.1 - 2.1 6.7 28.4 3.1 6.1 28.4 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG68415.1 - 2.1 6.4 28.2 2.9 6.0 28.2 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 GBG68415.1 - 2.6 6.9 27.7 3.9 6.4 27.7 1.2 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 GBG68415.1 - 2.8 6.6 13.1 4.1 6.1 13.1 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 GBG68415.1 - 4.2 5.4 26.2 6.8 4.7 26.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Fmp27 PF10344.9 GBG68415.1 - 4.2 5.3 6.4 5.4 5.0 6.4 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 RRN3 PF05327.11 GBG68415.1 - 4.9 5.6 15.3 7 5.1 15.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Lin-8 PF03353.15 GBG68415.1 - 6.5 6.2 12.5 10 5.5 12.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 GBG68415.1 - 6.5 5.5 12.0 8.7 5.1 12.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Helicase_C PF00271.31 GBG68416.1 - 5.1e-17 62.2 0.1 1.7e-16 60.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GBG68416.1 - 2.4e-10 41.0 5.2 7e-10 39.5 5.2 1.9 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 GBG68416.1 - 3.1e-10 39.9 0.0 6.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DEAD PF00270.29 GBG68416.1 - 2.5e-09 37.2 0.0 4e-08 33.2 0.0 2.8 3 1 0 3 3 3 1 DEAD/DEAH box helicase RQC PF09382.10 GBG68416.1 - 8.6e-08 32.0 0.0 0.0029 17.4 0.0 2.9 2 0 0 2 2 2 2 RQC domain DnaG_DnaB_bind PF08278.11 GBG68416.1 - 0.11 13.2 0.1 11 6.7 0.0 2.5 1 1 0 2 2 2 0 DNA primase DnaG DnaB-binding Pkinase PF00069.25 GBG68417.1 - 4.9e-36 124.4 0.0 3.6e-35 121.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG68417.1 - 6.8e-36 123.9 0.0 2.6e-34 118.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GBG68417.1 - 0.025 14.5 0.1 0.088 12.7 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family LRR_8 PF13855.6 GBG68418.1 - 0.0086 15.8 1.0 0.11 12.3 0.0 2.8 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 GBG68418.1 - 0.011 16.1 2.9 8.1 7.0 0.3 4.0 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Sporozoite_P67 PF05642.11 GBG68418.1 - 0.11 10.6 1.0 0.19 9.8 1.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.17 GBG68420.1 - 5.2 5.7 30.1 5 5.8 30.1 1.0 1 0 0 1 1 1 0 Presenilin DUF3439 PF11921.8 GBG68422.1 - 0.0031 17.5 3.1 0.0031 17.5 3.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Mucin PF01456.17 GBG68422.1 - 0.031 14.3 7.0 0.032 14.2 3.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF659 PF04937.15 GBG68423.1 - 4.3e-15 55.9 0.7 1.1e-14 54.6 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG68423.1 - 0.016 15.0 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Pkinase_Tyr PF07714.17 GBG68424.1 - 1e-31 110.2 0.0 8.7e-31 107.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG68424.1 - 1.1e-30 106.9 0.0 1.5e-29 103.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG68424.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP49_C PF12260.8 GBG68424.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 GBG68424.1 - 0.098 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF659 PF04937.15 GBG68426.1 - 4.1e-17 62.4 0.0 1.3e-16 60.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG68427.1 - 3.5e-07 30.7 0.1 1e-06 29.2 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68427.1 - 7.7e-06 26.5 0.1 2e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68427.1 - 0.00031 20.5 0.1 0.00053 19.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68427.1 - 0.0045 16.7 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG68427.1 - 0.018 14.7 0.3 0.037 13.7 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like PP2C PF00481.21 GBG68428.1 - 7.9e-44 150.2 0.3 3.8e-35 121.8 0.2 3.4 2 1 0 2 2 2 2 Protein phosphatase 2C Pkinase PF00069.25 GBG68428.1 - 5.9e-19 68.4 0.0 3.6e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG68428.1 - 0.0014 18.0 0.0 0.24 10.7 0.0 3.0 3 0 0 3 3 3 1 Protein tyrosine kinase SR-25 PF10500.9 GBG68429.1 - 0.11 12.1 11.9 2.1 7.9 4.0 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 GBG68429.1 - 0.12 10.9 0.2 0.33 9.4 0.0 1.6 1 1 1 2 2 2 0 Peptidase family S64 Period_C PF12114.8 GBG68429.1 - 0.14 11.8 6.5 0.74 9.4 5.9 2.1 2 0 0 2 2 2 0 Period protein 2/3C-terminal region CDT1_C PF16679.5 GBG68429.1 - 5.4 7.5 9.8 0.77 10.2 1.6 2.6 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Ribosomal_L13 PF00572.18 GBG68430.1 - 8.8e-49 164.9 0.1 8.8e-49 164.9 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 CT47 PF15623.6 GBG68431.1 - 0.086 12.7 4.2 0.15 11.9 4.2 1.3 1 0 0 1 1 1 0 Cancer/testis gene family 47 FeS_assembly_P PF01883.19 GBG68432.1 - 0.069 13.3 0.5 0.096 12.9 0.5 1.4 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein RVT_1 PF00078.27 GBG68433.1 - 5.4e-27 94.8 0.0 1.1e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68433.1 - 2.1e-21 75.8 0.0 2.4e-16 59.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68433.1 - 5.4e-15 55.2 0.4 5.4e-14 52.0 0.0 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG68433.1 - 7.8e-12 45.4 0.0 2.3e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG68433.1 - 1.7e-11 43.8 0.0 3.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG68433.1 - 5.3e-10 39.5 0.0 1.2e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG68433.1 - 0.0028 17.8 0.2 0.008 16.4 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG68433.1 - 0.0037 17.9 0.0 0.031 14.9 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease DUF4694 PF15765.5 GBG68434.1 - 0.15 12.1 0.5 0.23 11.5 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4694) DDE_Tnp_4 PF13359.6 GBG68435.1 - 8.2e-29 100.3 0.0 1.2e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68435.1 - 4.8e-12 45.9 0.0 6.7e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68435.1 - 0.022 14.4 3.7 0.75 9.4 0.0 3.2 3 1 0 3 3 3 0 Transposase DDE domain Maf_N PF08383.11 GBG68435.1 - 0.096 12.5 0.2 0.21 11.4 0.2 1.6 1 1 0 1 1 1 0 Maf N-terminal region RRN3 PF05327.11 GBG68435.1 - 0.18 10.3 0.1 0.24 9.9 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Myb_DNA-bind_4 PF13837.6 GBG68436.1 - 3.6e-05 24.1 3.0 6.4e-05 23.3 3.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Stig1 PF04885.13 GBG68437.1 - 3.2e-05 24.5 7.9 3.2e-05 24.5 7.9 3.5 2 1 0 3 3 3 1 Stigma-specific protein, Stig1 DUF4055 PF13264.6 GBG68437.1 - 0.98 9.6 6.0 2.2 8.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) DUF3213 PF11491.8 GBG68437.1 - 9.6 6.5 8.2 2.9 8.1 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3213) CDC45 PF02724.14 GBG68438.1 - 0.23 9.7 3.1 0.29 9.4 3.1 1.3 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG68438.1 - 0.28 11.3 17.4 0.48 10.5 17.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.12 GBG68438.1 - 7.4 5.0 17.8 4.1 5.9 14.4 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Retrotrans_gag PF03732.17 GBG68439.1 - 0.0014 18.8 3.6 0.0015 18.8 0.1 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG68439.1 - 0.008 15.9 0.9 0.024 14.4 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) AIP3 PF03915.13 GBG68439.1 - 0.051 12.7 0.5 0.084 12.0 0.5 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Preseq_ALAS PF09029.10 GBG68439.1 - 0.2 12.1 0.2 0.2 12.1 0.2 2.5 3 1 0 3 3 3 0 5-aminolevulinate synthase presequence RT_RNaseH PF17917.1 GBG68440.1 - 1.2e-20 73.8 0.0 5.5e-20 71.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68440.1 - 8.7e-20 70.6 0.0 8.4e-19 67.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68440.1 - 1.9e-18 66.3 0.4 5.2e-18 64.9 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68440.1 - 2e-16 60.3 0.0 6e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG68440.1 - 1.5e-08 35.2 0.0 3.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68440.1 - 1.7e-08 34.9 0.0 3.9e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG68440.1 - 0.00021 20.9 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG68440.1 - 0.00029 20.6 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68440.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG68440.1 - 0.15 12.3 0.3 0.38 11.0 0.3 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG68441.1 - 2.6e-21 76.2 0.0 7.8e-21 74.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG68441.1 - 6.6e-07 29.9 0.0 2.9e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68441.1 - 1.9e-06 28.3 0.0 8.8e-06 26.2 0.0 2.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG68441.1 - 1.2e-05 25.1 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG68441.1 - 0.00012 22.2 2.8 0.0007 19.8 0.1 3.1 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG68441.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG68445.1 - 6.4e-22 77.8 0.0 1.4e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68445.1 - 6.9e-22 77.4 0.0 1.4e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Topo_Zn_Ribbon PF08272.11 GBG68445.1 - 0.032 13.9 0.3 0.069 12.8 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG68445.1 - 0.062 13.4 1.9 0.13 12.4 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle ATE_N PF04376.13 GBG68445.1 - 0.71 10.3 4.1 0.93 9.9 0.0 2.8 3 0 0 3 3 3 0 Arginine-tRNA-protein transferase, N terminus MtrE PF04206.12 GBG68447.1 - 2.1 7.6 11.7 3 7.1 11.7 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E Hirudin PF00713.17 GBG68448.1 - 0.1 12.9 5.0 0.17 12.2 0.4 2.8 2 0 0 2 2 2 0 Hirudin NAM-associated PF14303.6 GBG68448.1 - 4.6 7.9 8.9 2 9.1 3.6 2.7 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain DDE_Tnp_4 PF13359.6 GBG68449.1 - 1.1e-31 109.6 0.0 1.7e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68449.1 - 2.6e-14 53.3 0.0 1.1e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68449.1 - 1.5e-06 28.0 0.2 0.055 13.1 0.0 3.1 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG68449.1 - 0.067 13.6 0.1 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain FGF-BP1 PF06473.12 GBG68451.1 - 0.86 9.4 9.4 0.089 12.6 3.3 2.2 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Lin-8 PF03353.15 GBG68451.1 - 7.3 6.0 9.5 12 5.4 9.0 1.5 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist Myb_DNA-bind_4 PF13837.6 GBG68452.1 - 2.9e-09 37.2 0.7 6e-09 36.2 0.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG68453.1 - 1.1e-31 109.7 0.0 1.8e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68453.1 - 4.7e-13 49.2 0.0 7.4e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68453.1 - 0.013 15.1 0.1 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 Transposase DDE domain Herpes_capsid PF06112.11 GBG68454.1 - 2 8.4 17.6 0.033 14.3 9.3 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein gag-asp_proteas PF13975.6 GBG68455.1 - 3.5e-06 27.5 0.0 8e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68455.1 - 0.00053 20.6 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68455.1 - 0.00086 19.1 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68455.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG68456.1 - 1.9e-19 69.9 0.0 4.7e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68456.1 - 1.2e-18 67.0 0.0 2.3e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68456.1 - 3.1e-17 62.4 0.9 8.1e-17 61.1 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68456.1 - 1.6e-13 50.9 0.0 6.8e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG68456.1 - 4.1e-09 36.3 0.0 7.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG68456.1 - 3.3e-06 27.6 0.1 9e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68456.1 - 3.2e-05 24.5 0.1 7.9e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68456.1 - 0.00095 19.0 0.1 0.0021 17.8 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG68456.1 - 0.018 15.2 0.6 0.045 14.0 0.6 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 GBG68456.1 - 0.03 14.1 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG68456.1 - 0.22 11.7 1.9 0.56 10.4 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG68459.1 - 8.2e-05 22.5 3.7 0.00023 21.1 3.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG68459.1 - 0.001 18.8 4.6 0.002 17.9 4.6 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF1967 PF09269.11 GBG68459.1 - 0.012 15.5 0.4 0.11 12.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) P5-ATPase PF12409.8 GBG68459.1 - 0.49 10.5 4.7 0.63 10.2 2.9 2.0 2 0 0 2 2 2 0 P5-type ATPase cation transporter Ycf1 PF05758.12 GBG68459.1 - 0.71 7.7 9.4 1.1 7.0 9.4 1.2 1 0 0 1 1 1 0 Ycf1 AFT PF08731.11 GBG68459.1 - 7.8 6.9 12.9 1.7 9.1 0.1 3.3 3 1 0 3 3 3 0 Transcription factor AFT TcdA_TcdB PF12919.7 GBG68460.1 - 0.024 13.9 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Pkinase PF00069.25 GBG68462.1 - 1e-14 54.6 0.0 2.4e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG68462.1 - 7.7e-07 28.7 0.0 1.9e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 GBG68463.1 - 1.9e-25 89.7 0.0 3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68463.1 - 1.9e-12 47.1 0.0 5.9e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68463.1 - 9.6e-05 22.6 0.0 0.00025 21.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG68463.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease HSP70 PF00012.20 GBG68464.1 - 1.6e-158 528.6 0.0 1.9e-158 528.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG68464.1 - 6.6e-10 38.3 0.9 0.00094 18.1 0.2 3.8 3 1 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 GBG68464.1 - 0.02 15.3 1.1 41 4.7 0.0 4.1 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 GBG68464.1 - 0.051 12.8 0.4 0.29 10.3 0.4 2.0 1 1 0 1 1 1 0 StbA protein DDR PF08841.10 GBG68464.1 - 0.2 10.6 1.6 5.4 5.9 1.6 2.3 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 GBG68465.1 - 1.4e-94 317.4 2.8 9.1e-90 301.6 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG68465.1 - 0.00045 19.2 5.9 0.12 11.1 0.2 3.8 3 1 0 3 3 3 2 MreB/Mbl protein HSP70 PF00012.20 GBG68466.1 - 1.3e-124 416.6 0.6 5.9e-99 331.9 1.7 3.5 2 2 1 3 3 3 2 Hsp70 protein Integrase_H2C2 PF17921.1 GBG68466.1 - 5.2e-15 55.3 0.1 1.1e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain MreB_Mbl PF06723.13 GBG68466.1 - 2e-06 26.8 0.2 0.00047 19.1 0.1 2.7 2 0 0 2 2 2 2 MreB/Mbl protein rve PF00665.26 GBG68466.1 - 6.5e-05 23.1 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG68466.1 - 0.00074 20.0 0.0 0.0026 18.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG68466.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DDR PF08841.10 GBG68466.1 - 0.089 11.8 0.8 0.57 9.1 0.8 2.2 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Asp_protease_2 PF13650.6 GBG68466.1 - 0.11 13.2 0.0 0.34 11.6 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Presenilin PF01080.17 GBG68466.1 - 4.8 5.8 9.7 8.6 5.0 9.7 1.3 1 0 0 1 1 1 0 Presenilin SlyX PF04102.12 GBG68469.1 - 0.26 11.9 1.5 1.4 9.6 0.1 2.6 3 0 0 3 3 3 0 SlyX DHR10 PF18595.1 GBG68469.1 - 0.47 10.5 4.7 0.15 12.1 0.9 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Histone PF00125.24 GBG68470.1 - 6.6e-19 68.6 0.0 1.5e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HAT PF02184.16 GBG68471.1 - 2.4e-23 81.8 91.3 1.6e-08 34.4 1.2 16.0 17 1 0 17 17 17 10 HAT (Half-A-TPR) repeat Suf PF05843.14 GBG68471.1 - 1.3e-17 64.7 16.8 4.9e-05 23.5 0.4 6.9 3 2 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_14 PF13428.6 GBG68471.1 - 3.1e-13 49.4 37.1 0.026 15.3 0.1 12.4 9 5 3 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 GBG68471.1 - 2e-10 41.0 0.0 0.17 12.4 0.0 7.3 6 1 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG68471.1 - 4.1e-07 29.7 2.0 4.2 7.8 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG68471.1 - 6.7e-07 29.3 0.1 0.94 10.0 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG68471.1 - 5.9e-06 26.0 11.6 1.6 9.0 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat NRDE-2 PF08424.10 GBG68471.1 - 0.00043 19.5 29.7 0.013 14.6 0.0 7.1 3 3 4 7 7 7 3 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 GBG68471.1 - 0.025 14.5 21.4 0.092 12.7 1.8 6.4 4 3 1 5 5 5 0 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 GBG68471.1 - 0.17 12.6 28.7 8.2 7.2 0.1 8.0 8 2 1 9 9 9 0 Tetratricopeptide repeat Sod_Cu PF00080.20 GBG68473.1 - 5.7e-48 162.7 5.4 7.2e-48 162.4 5.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) RT_RNaseH_2 PF17919.1 GBG68475.1 - 2.2e-27 95.0 0.0 4.7e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68475.1 - 2.7e-27 95.1 0.0 5.8e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68475.1 - 0.00043 19.9 0.1 0.00077 19.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-ATPase_G PF03179.15 GBG68475.1 - 0.0033 17.9 18.0 0.0033 17.9 18.0 1.7 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit Phage_GPO PF05929.11 GBG68475.1 - 0.35 10.4 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase CemA PF03040.14 GBG68475.1 - 0.53 10.2 2.4 1.1 9.1 2.4 1.4 1 0 0 1 1 1 0 CemA family CENP-H PF05837.12 GBG68475.1 - 6 7.3 18.7 0.48 10.9 12.5 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) GGACT PF06094.12 GBG68477.1 - 6.6e-13 49.3 0.0 1.1e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AMP-binding PF00501.28 GBG68478.1 - 1.8e-74 250.9 0.1 3.4e-74 250.0 0.1 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GBG68478.1 - 8.7e-13 49.1 0.2 1.8e-12 48.0 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF308 PF03729.13 GBG68480.1 - 1.4e-14 54.1 43.0 2.4e-09 37.4 18.1 3.3 1 1 2 3 3 3 2 Short repeat of unknown function (DUF308) YqhR PF11085.8 GBG68480.1 - 2.6 7.9 11.5 0.093 12.6 3.7 2.3 1 1 2 3 3 3 0 Conserved membrane protein YqhR DUF4637 PF15470.6 GBG68481.1 - 0.00065 19.5 4.2 0.00065 19.5 4.2 7.2 6 1 1 7 7 7 1 Domain of unknown function (DUF4637) Astro_capsid_N PF03115.14 GBG68481.1 - 1.2 7.7 3.5 2.4 6.8 3.5 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor AMP-binding PF00501.28 GBG68482.1 - 7.4e-105 351.0 0.0 9.4e-105 350.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GBG68482.1 - 8e-07 30.0 2.3 2e-05 25.5 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF848 PF05852.11 GBG68483.1 - 0.033 14.3 3.9 0.042 14.0 3.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) NBD_C PF17042.5 GBG68483.1 - 0.16 12.5 6.3 1.9 9.0 0.9 2.1 1 1 1 2 2 2 0 Nucleotide-binding C-terminal domain Herpes_UL25 PF01499.16 GBG68483.1 - 0.16 10.5 2.3 0.19 10.2 2.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family FUSC PF04632.12 GBG68483.1 - 1.9 6.9 4.9 2.3 6.6 4.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Aminotran_1_2 PF00155.21 GBG68484.1 - 3.8e-38 131.6 0.0 2.2e-37 129.1 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class I and II Alliinase_C PF04864.13 GBG68484.1 - 6.2e-06 25.3 0.0 3.8e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Allinase Isochorismatase PF00857.20 GBG68485.1 - 1.4e-28 100.3 0.0 1.9e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Ion_trans_2 PF07885.16 GBG68485.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Ion channel Isochorismatase PF00857.20 GBG68486.1 - 9.1e-28 97.6 0.0 1.1e-27 97.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family RVP_2 PF08284.11 GBG68487.1 - 1.6e-07 31.1 0.0 3.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68487.1 - 3e-06 27.8 0.0 1.6e-05 25.4 0.0 2.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68487.1 - 3.1e-05 24.5 0.0 0.00034 21.1 0.0 2.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG68487.1 - 0.00038 20.2 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CDH1_2_SANT_HL1 PF18375.1 GBG68487.1 - 0.04 14.6 0.8 0.04 14.6 0.8 2.4 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 MAT1 PF06391.13 GBG68488.1 - 2.9e-28 99.1 7.0 3.2e-28 99.0 7.0 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 RT_RNaseH_2 PF17919.1 GBG68489.1 - 3.9e-31 107.1 0.0 9.3e-16 57.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68489.1 - 1.9e-30 105.2 0.0 3.9e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68489.1 - 3e-15 56.3 0.1 2.4e-14 53.4 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG68489.1 - 1.7e-09 37.5 0.0 3.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG68489.1 - 1.3e-08 35.0 0.0 6.7e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Integrase core domain Coatomer_WDAD PF04053.14 GBG68490.1 - 9e-12 44.8 0.1 3e-06 26.6 0.0 4.0 4 1 0 4 4 4 2 Coatomer WD associated region WD40 PF00400.32 GBG68490.1 - 1.4e-06 28.9 4.5 0.17 12.8 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat RT_RNaseH PF17917.1 GBG68491.1 - 1.5e-22 79.8 0.0 3.3e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68491.1 - 5e-22 77.8 0.0 1.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68491.1 - 6.6e-21 74.9 0.2 1.6e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG68491.1 - 1e-12 48.0 0.5 2.3e-12 46.8 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68491.1 - 1.5e-06 28.4 0.3 6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG68491.1 - 2e-06 27.6 0.0 5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68491.1 - 3.1e-05 24.5 0.0 6.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG68491.1 - 5e-05 23.5 0.3 5e-05 23.5 0.3 2.9 4 0 0 4 4 4 1 Retrotransposon gag protein Tudor-knot PF11717.8 GBG68491.1 - 0.00016 21.5 0.0 0.0004 20.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain gag-asp_proteas PF13975.6 GBG68491.1 - 0.015 15.9 0.0 0.034 14.7 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_Tnp_4 PF13359.6 GBG68492.1 - 6.3e-19 68.2 0.0 1.5e-18 67.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68492.1 - 8.2e-08 32.1 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68492.1 - 0.018 14.7 0.0 0.055 13.1 0.0 1.8 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG68493.1 - 9.8e-10 38.7 1.2 4.5e-08 33.4 0.9 2.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG68493.1 - 0.0032 17.5 0.8 0.0094 16.0 0.8 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Transcrip_act PF04949.13 GBG68493.1 - 0.051 13.5 0.3 0.13 12.2 0.2 1.6 2 0 0 2 2 2 0 Transcriptional activator MADF_DNA_bdg PF10545.9 GBG68493.1 - 0.12 12.8 0.1 0.53 10.6 0.1 2.1 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3915 PF13054.6 GBG68493.1 - 1.3 9.0 4.2 0.42 10.6 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) MAD PF05557.13 GBG68493.1 - 2.5 6.4 5.4 0.37 9.1 1.2 1.6 2 0 0 2 2 2 0 Mitotic checkpoint protein Jnk-SapK_ap_N PF09744.9 GBG68494.1 - 0.056 13.7 13.8 0.082 13.1 13.8 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Syntaxin-18_N PF10496.9 GBG68494.1 - 1.5 9.1 6.2 6.8 7.0 6.2 2.0 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus RT_RNaseH_2 PF17919.1 GBG68495.1 - 1.4e-27 95.6 0.0 4.3e-27 94.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68495.1 - 2.3e-24 85.7 0.0 6.2e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG68495.1 - 2.9e-07 31.0 0.0 7.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68495.1 - 1.2e-06 29.0 0.0 4.2e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG68495.1 - 1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG68495.1 - 0.00014 21.5 0.0 0.00038 20.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG68495.1 - 0.00041 20.1 0.0 0.00082 19.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG68495.1 - 0.083 13.2 0.1 0.36 11.1 0.1 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein TMF_TATA_bd PF12325.8 GBG68495.1 - 0.27 11.4 0.0 0.27 11.4 0.0 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Glyco_transf_34 PF05637.12 GBG68496.1 - 4.9e-26 91.9 6.9 3.4e-23 82.6 5.6 2.8 2 1 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family Glyco_transf_34 PF05637.12 GBG68498.1 - 1e-25 90.9 7.2 5.4e-25 88.5 7.2 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 GBG68498.1 - 0.098 12.6 10.0 0.45 10.5 8.8 2.2 2 1 0 2 2 2 0 Nucleotide-diphospho-sugar transferase DUF2385 PF09539.10 GBG68499.1 - 0.024 15.1 0.1 0.95 10.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) bZIP_1 PF00170.21 GBG68499.1 - 0.025 14.7 0.2 0.11 12.7 0.2 2.1 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 GBG68499.1 - 0.044 13.6 0.6 0.044 13.6 0.6 1.9 2 0 0 2 2 2 0 Septum formation initiator HALZ PF02183.18 GBG68499.1 - 0.1 12.9 1.2 0.32 11.3 1.2 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 GBG68499.1 - 0.33 11.4 0.2 0.33 11.4 0.2 2.9 4 0 0 4 4 4 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 GBG68499.1 - 2.9 8.2 6.9 0.77 10.1 0.2 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 GBG68500.1 - 0.00033 20.9 8.2 0.00033 20.9 8.2 1.9 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 Atg14 PF10186.9 GBG68500.1 - 0.1 11.7 2.4 0.17 10.9 2.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YqzH PF14164.6 GBG68500.1 - 0.11 12.6 0.2 0.3 11.2 0.2 1.7 1 0 0 1 1 1 0 YqzH-like protein DUF3347 PF11827.8 GBG68500.1 - 0.2 11.8 2.0 0.38 10.9 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Myb_DNA-bind_4 PF13837.6 GBG68501.1 - 9.8e-06 25.9 1.5 2e-05 24.9 1.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TetR_C_24 PF17932.1 GBG68501.1 - 0.11 12.8 0.7 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ING PF12998.7 GBG68502.1 - 3.1e-21 75.8 0.3 4.5e-21 75.3 0.3 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GBG68502.1 - 6.4e-07 29.2 10.2 1.3e-06 28.2 10.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GBG68502.1 - 0.88 9.9 7.0 0.15 12.3 2.8 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain Vac14_Fab1_bd PF12755.7 GBG68503.1 - 5.3e-06 26.9 1.6 5.4 7.7 0.0 5.2 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GBG68503.1 - 3.2e-05 23.8 19.0 8.3 7.0 0.3 9.0 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 GBG68503.1 - 9.2e-05 22.8 0.9 20 5.7 0.1 5.2 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 GBG68503.1 - 1.3 9.7 13.8 45 4.7 0.2 6.4 5 1 1 6 6 6 0 HEAT-like repeat DUF4982 PF16355.5 GBG68504.1 - 0.044 13.7 0.0 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4982) SLX9 PF15341.6 GBG68505.1 - 1.2e-07 32.2 2.2 2.3e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 NPR1_interact PF15699.5 GBG68505.1 - 0.011 16.4 0.2 0.02 15.5 0.2 1.5 1 0 0 1 1 1 0 NPR1 interacting SAD_SRA PF02182.17 GBG68506.1 - 2.5e-32 111.8 2.6 2.6e-31 108.4 2.6 2.5 1 1 0 1 1 1 1 SAD/SRA domain MT0933_antitox PF14013.6 GBG68506.1 - 0.72 10.2 11.9 0.058 13.7 6.3 2.2 2 0 0 2 2 2 0 MT0933-like antitoxin protein Defensin_5 PF18251.1 GBG68506.1 - 0.89 9.7 4.6 9.1 6.5 0.2 2.7 2 0 0 2 2 2 0 Fungal defensin Copsin Piwi PF02171.17 GBG68507.1 - 2.4e-85 286.4 0.0 5.5e-85 285.2 0.0 1.5 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 GBG68507.1 - 3.1e-26 92.6 0.0 5.6e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 GBG68507.1 - 1.2e-20 73.7 0.0 1.9e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 GBG68507.1 - 1.5e-13 50.2 0.0 4e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 GBG68507.1 - 7.6e-11 42.2 0.0 3.3e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 GBG68507.1 - 9.2e-08 32.2 0.1 2.5e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 Mid domain of argonaute QH-AmDH_gamma PF08992.11 GBG68507.1 - 0.11 12.6 0.5 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 Quinohemoprotein amine dehydrogenase, gamma subunit RVT_1 PF00078.27 GBG68508.1 - 7.3e-19 68.2 0.1 1.7e-18 67.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG68508.1 - 5.2e-09 36.0 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68508.1 - 6.8e-08 33.1 0.0 1.8e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Thioredoxin PF00085.20 GBG68508.1 - 8.4e-07 28.9 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin gag-asp_proteas PF13975.6 GBG68508.1 - 3.3e-06 27.5 0.0 8.9e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG68508.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease HyaE PF07449.11 GBG68508.1 - 0.0082 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 GBG68508.1 - 0.12 12.9 0.1 5.4 7.5 0.0 3.5 4 1 0 4 4 4 0 Thioredoxin-like domain GHMP_kinases_N PF00288.26 GBG68509.1 - 9.2e-15 54.6 0.1 3.7e-14 52.7 0.1 2.2 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GBG68509.1 - 1.1e-06 28.9 0.0 1.1e-06 28.9 0.0 2.6 3 0 0 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 GBG68509.1 - 0.00055 19.4 0.2 0.0015 18.1 0.2 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature I_LWEQ PF01608.17 GBG68509.1 - 0.0017 18.6 0.2 0.0032 17.7 0.2 1.4 1 0 0 1 1 1 1 I/LWEQ domain NPR3 PF03666.13 GBG68511.1 - 0.25 10.1 1.5 0.4 9.4 1.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RibD_C PF01872.17 GBG68512.1 - 1.1 9.0 8.6 21 4.9 8.6 2.1 1 1 0 1 1 1 0 RibD C-terminal domain FERM_f0 PF16511.5 GBG68512.1 - 1.1 9.6 9.0 24 5.3 0.4 3.5 1 1 2 3 3 3 0 N-terminal or F0 domain of Talin-head FERM Clathrin_propel PF01394.20 GBG68512.1 - 7.6 7.0 10.4 9.7 6.7 0.4 3.6 3 1 1 4 4 4 0 Clathrin propeller repeat DUF287 PF03384.14 GBG68513.1 - 0.49 10.8 6.6 0.08 13.4 1.5 2.3 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 CoA_binding PF02629.19 GBG68514.1 - 3.6e-31 107.7 0.8 3.6e-31 107.7 0.8 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 GBG68514.1 - 3.5e-23 82.1 0.3 6.2e-23 81.3 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 GBG68514.1 - 9.3e-11 41.7 0.0 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GBG68514.1 - 0.00033 21.1 0.0 0.00081 19.9 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Sugar_tr PF00083.24 GBG68515.1 - 7.9e-32 110.7 8.0 5.9e-20 71.6 3.1 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 GBG68515.1 - 3.8e-21 75.4 20.6 5.6e-10 38.7 13.6 3.7 4 0 0 4 4 4 3 Major Facilitator Superfamily Ca_hom_mod PF14798.6 GBG68515.1 - 0.23 10.5 0.7 0.98 8.5 0.0 2.0 2 0 0 2 2 2 0 Calcium homeostasis modulator WD40 PF00400.32 GBG68516.1 - 2.7e-55 183.1 19.6 5.9e-07 30.1 0.2 10.8 10 0 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG68516.1 - 2.7e-15 56.5 6.2 0.07 13.4 0.0 8.7 5 3 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 GBG68516.1 - 4.1e-15 56.0 0.2 7.9e-15 55.1 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family PALB2_WD40 PF16756.5 GBG68516.1 - 3.3e-07 29.5 1.2 0.024 13.6 0.1 4.0 4 0 0 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 GBG68516.1 - 2.1e-05 23.4 1.4 0.78 8.3 0.3 4.3 4 1 0 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GBG68516.1 - 4.7e-05 22.5 6.4 5.4 5.9 0.0 7.4 6 2 3 9 9 9 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GBG68516.1 - 0.00037 19.9 0.0 0.26 10.6 0.0 4.0 3 2 0 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 GBG68516.1 - 0.01 14.6 0.1 1.2 7.9 0.0 3.8 5 1 0 5 5 5 0 Nup133 N terminal like BBS2_Mid PF14783.6 GBG68516.1 - 0.064 13.3 0.2 2.4 8.2 0.0 3.9 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Ala_racemase_C PF00842.21 GBG68516.1 - 0.066 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain TFIIIC_delta PF12657.7 GBG68516.1 - 0.13 12.2 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term CXCXC PF03128.14 GBG68516.1 - 0.32 11.5 1.7 0.54 10.8 0.2 2.1 2 0 0 2 2 2 0 CXCXC repeat Nramp PF01566.18 GBG68517.1 - 3.4e-117 391.4 14.4 5.9e-117 390.6 14.4 1.4 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Asp_protease_2 PF13650.6 GBG68519.1 - 1.7e-09 38.2 0.0 1.3e-08 35.3 0.0 2.5 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68519.1 - 6.2e-08 33.1 0.0 1.8e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG68519.1 - 5.4e-07 29.5 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG68519.1 - 1.5e-05 24.6 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG68519.1 - 0.0002 21.2 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG68519.1 - 0.0008 19.6 0.1 0.069 13.4 0.0 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein Myb_DNA-bind_4 PF13837.6 GBG68520.1 - 0.00033 21.0 0.3 0.00067 20.0 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG68521.1 - 6.2e-22 78.0 0.0 8.7e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68521.1 - 6e-15 55.4 0.0 9e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68521.1 - 0.011 15.4 1.8 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Beta_helix PF13229.6 GBG68522.1 - 0.00064 19.6 2.6 0.0015 18.4 2.2 1.9 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG68522.1 - 0.0033 17.8 35.2 0.2 12.2 0.7 7.1 7 0 0 7 7 7 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat GAS PF13851.6 GBG68523.1 - 0.00059 19.2 27.5 0.016 14.6 8.8 3.1 2 1 1 3 3 3 3 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 GBG68523.1 - 0.00092 19.3 31.9 0.11 12.6 15.5 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein HIP1_clath_bdg PF16515.5 GBG68523.1 - 0.025 15.2 33.3 0.14 12.8 3.8 3.8 1 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 GBG68523.1 - 0.057 13.9 27.8 0.2 12.1 16.0 2.1 1 1 1 2 2 2 0 Fez1 MAD PF05557.13 GBG68523.1 - 0.15 10.4 22.1 0.26 9.6 22.1 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.11 GBG68523.1 - 0.19 10.6 28.8 0.63 8.9 10.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 GBG68523.1 - 0.25 11.1 19.1 0.022 14.6 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 GBG68523.1 - 0.29 11.4 16.9 4.2 7.7 1.2 3.4 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 GBG68523.1 - 0.3 11.3 30.4 0.28 11.4 7.5 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 GBG68523.1 - 0.3 11.3 34.8 0.052 13.8 13.8 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 GBG68523.1 - 0.36 10.8 28.2 0.92 9.5 10.2 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 GBG68523.1 - 0.4 11.6 25.2 2.1 9.3 2.9 3.5 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain eIF-4B PF06273.11 GBG68523.1 - 0.45 9.5 7.5 0.047 12.7 2.2 1.8 1 1 1 2 2 2 0 Plant specific eukaryotic initiation factor 4B THOC7 PF05615.13 GBG68523.1 - 0.95 9.7 30.3 1.2e+02 3.0 21.9 3.7 1 1 1 2 2 2 0 Tho complex subunit 7 NUDE_C PF04880.13 GBG68523.1 - 1.1 9.7 20.5 1.3 9.5 8.4 2.7 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Leu_zip PF15294.6 GBG68523.1 - 1.2 8.5 22.3 1.5 8.2 9.5 2.2 1 1 1 2 2 2 0 Leucine zipper APG6_N PF17675.1 GBG68523.1 - 1.4 9.5 34.1 0.46 11.0 4.8 3.3 1 1 1 2 2 1 0 Apg6 coiled-coil region Tup_N PF08581.10 GBG68523.1 - 2.2 8.6 18.8 0.76 10.1 3.4 3.5 1 1 1 3 3 3 0 Tup N-terminal Occludin_ELL PF07303.13 GBG68523.1 - 3.2 8.5 10.7 2.6 8.8 0.8 3.0 2 1 1 3 3 3 0 Occludin homology domain DUF4407 PF14362.6 GBG68523.1 - 4 6.7 24.9 37 3.5 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 GBG68523.1 - 4.2 7.7 30.0 0.19 12.1 6.8 3.1 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) TFIIA PF03153.13 GBG68523.1 - 4.4 7.2 15.7 5.7 6.8 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ADIP PF11559.8 GBG68523.1 - 5.4 7.1 32.3 1.9 8.6 7.6 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding betaPIX_CC PF16523.5 GBG68523.1 - 6.2 6.7 13.2 0.72 9.7 0.2 3.3 1 1 1 3 3 3 0 betaPIX coiled coil Surfac_D-trimer PF09006.11 GBG68523.1 - 6.9 6.7 7.7 0.33 10.9 0.4 2.7 3 0 0 3 3 1 0 Lung surfactant protein D coiled-coil trimerisation DUF2203 PF09969.9 GBG68523.1 - 8.2 7.2 17.6 19 6.0 4.1 2.8 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DnaJ PF00226.31 GBG68524.1 - 1.8e-13 50.4 0.3 3.3e-07 30.3 0.1 2.3 2 0 0 2 2 2 2 DnaJ domain zf-CSL PF05207.13 GBG68524.1 - 4.3e-12 45.6 6.6 9.9e-12 44.4 6.6 1.7 1 0 0 1 1 1 1 CSL zinc finger SAD_SRA PF02182.17 GBG68525.1 - 8.3e-25 87.3 2.1 1.5e-24 86.5 2.1 1.4 1 0 0 1 1 1 1 SAD/SRA domain RT_RNaseH_2 PF17919.1 GBG68526.1 - 2.4e-25 88.5 0.0 5.1e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68526.1 - 1.7e-22 80.0 0.0 2.7e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68526.1 - 1.6e-21 76.5 0.0 3.9e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG68526.1 - 0.016 15.5 0.1 0.14 12.5 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein zf-NF-X1 PF01422.17 GBG68527.1 - 3.1e-10 39.9 106.5 3.9e-06 26.8 14.8 17.6 19 1 0 19 19 19 11 NF-X1 type zinc finger Cupin_3 PF05899.12 GBG68528.1 - 1.8 8.3 8.6 7.2 6.4 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF861) Glyco_transf_8 PF01501.20 GBG68529.1 - 1e-09 38.3 0.4 2.5e-05 24.0 0.1 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GBG68529.1 - 0.055 12.8 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative DUF2457 PF10446.9 GBG68529.1 - 5.3 6.1 11.4 8.2 5.5 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 GBG68530.1 - 7.6 5.8 38.5 9.3 5.6 38.5 1.1 1 0 0 1 1 1 0 SDA1 BORG_CEP PF14957.6 GBG68530.1 - 7.7 7.7 8.9 13 7.0 8.9 1.4 1 0 0 1 1 1 0 Cdc42 effector RVT_1 PF00078.27 GBG68531.1 - 0.034 13.6 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) 2-Hacid_dh_C PF02826.19 GBG68532.1 - 5.8e-61 204.9 0.0 1.2e-60 203.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GBG68532.1 - 8.1e-35 119.4 0.4 1.8e-34 118.3 0.4 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 GBG68532.1 - 2.3e-07 30.5 0.6 7.8e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 ACT domain IlvN PF07991.12 GBG68532.1 - 0.00043 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 GBG68532.1 - 0.0016 18.5 0.1 0.0037 17.3 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.21 GBG68532.1 - 0.023 14.4 0.6 0.053 13.2 0.1 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XdhC_C PF13478.6 GBG68532.1 - 0.027 15.0 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Ribosomal_S13 PF00416.22 GBG68533.1 - 3e-31 108.5 0.1 3.4e-31 108.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 GBG68533.1 - 0.047 12.4 0.0 0.054 12.2 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Malic_M PF03949.15 GBG68534.1 - 2.7e-168 557.8 0.6 3.2e-83 279.0 0.0 2.2 2 0 0 2 2 2 2 Malic enzyme, NAD binding domain malic PF00390.19 GBG68534.1 - 2.7e-133 441.2 0.0 4.3e-67 225.4 0.0 2.4 2 0 0 2 2 2 2 Malic enzyme, N-terminal domain GHL10 PF02638.15 GBG68534.1 - 0.16 11.0 0.0 8.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase-like 10 Shikimate_DH PF01488.20 GBG68534.1 - 0.23 11.5 1.1 18 5.4 0.1 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CPCFC PF17223.3 GBG68534.1 - 1.8 8.4 6.0 10 6.0 1.1 2.6 2 0 0 2 2 2 0 Cuticle protein CPCFC ATG16 PF08614.11 GBG68535.1 - 3.8e-05 24.0 5.1 3.8e-05 24.0 5.1 2.5 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) Filament PF00038.21 GBG68535.1 - 0.00018 21.2 6.1 0.00018 21.2 6.1 2.0 2 0 0 2 2 2 1 Intermediate filament protein Tup_N PF08581.10 GBG68535.1 - 0.0044 17.3 1.0 0.0044 17.3 1.0 2.2 2 0 0 2 2 2 1 Tup N-terminal ADIP PF11559.8 GBG68535.1 - 0.0056 16.8 0.8 0.017 15.2 0.8 1.8 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Nup54 PF13874.6 GBG68535.1 - 0.013 15.7 4.6 0.24 11.5 3.4 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TMF_DNA_bd PF12329.8 GBG68535.1 - 0.019 14.9 9.7 0.019 14.9 9.7 3.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 GBG68535.1 - 0.024 14.9 3.7 0.024 14.9 3.7 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) Cep57_MT_bd PF06657.13 GBG68535.1 - 0.066 13.7 5.5 0.21 12.1 3.8 2.9 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 BLOC1_2 PF10046.9 GBG68535.1 - 0.15 12.3 4.2 1.1 9.5 1.7 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 GBG68535.1 - 0.2 11.7 6.2 1 9.4 2.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HALZ PF02183.18 GBG68535.1 - 0.45 10.8 4.3 0.24 11.7 0.4 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper TSC22 PF01166.18 GBG68535.1 - 0.76 10.1 5.1 0.38 11.1 1.5 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family CCDC106 PF15794.5 GBG68535.1 - 1 9.0 12.9 1.6 8.4 3.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Spc7 PF08317.11 GBG68535.1 - 2.4 6.9 21.7 0.0089 14.9 6.4 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein COG2 PF06148.11 GBG68535.1 - 4.2 7.5 11.8 0.62 10.2 5.1 2.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.8 GBG68535.1 - 4.4 6.5 10.0 0.052 12.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 GBG68535.1 - 6.4 6.6 9.3 0.4 10.5 2.5 2.5 2 1 1 3 3 2 0 Septum formation initiator rve PF00665.26 GBG68536.1 - 1.2e-14 54.5 0.3 2.5e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG68536.1 - 2.3e-08 34.0 0.3 6.3e-08 32.6 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG68536.1 - 0.00073 19.7 0.1 0.0018 18.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger BUD22 PF09073.10 GBG68536.1 - 0.0053 16.1 12.1 0.0068 15.8 12.1 1.1 1 0 0 1 1 1 1 BUD22 MLVIN_C PF18697.1 GBG68536.1 - 0.052 13.6 0.2 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Na_trans_assoc PF06512.13 GBG68536.1 - 0.08 13.2 7.3 0.12 12.6 7.3 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG68536.1 - 0.13 11.6 19.0 0.21 11.0 19.0 1.3 1 0 0 1 1 1 0 SDA1 DDE_Tnp_ISL3 PF01610.17 GBG68536.1 - 0.14 11.8 0.2 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 Transposase DUF4611 PF15387.6 GBG68538.1 - 0.044 14.0 1.7 0.044 14.0 1.7 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4611) malic PF00390.19 GBG68540.1 - 1.7e-67 226.7 0.0 2.4e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 GBG68540.1 - 1.1e-53 182.1 0.0 1.8e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GBG68541.1 - 1.4e-64 217.2 0.0 2.3e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 GBG68541.1 - 1.1e-59 201.8 0.0 2e-59 201.0 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain RVT_1 PF00078.27 GBG68541.1 - 1e-05 25.2 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HypA PF01155.19 GBG68541.1 - 0.21 11.6 0.1 0.44 10.6 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RT_RNaseH_2 PF17919.1 GBG68542.1 - 5.7e-28 96.9 0.0 7.8e-27 93.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68542.1 - 1.4e-27 96.0 0.3 2.1e-26 92.3 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68542.1 - 1.3e-19 70.0 0.5 2.9e-19 68.9 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68542.1 - 1.9e-17 63.5 0.0 6.6e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG68542.1 - 4.2e-10 39.5 0.7 4.6e-06 26.3 0.0 2.7 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG68542.1 - 6.1e-07 29.3 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68542.1 - 1.2e-05 25.9 0.0 2.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG68542.1 - 0.00047 20.3 0.1 0.0012 19.0 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG68542.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG68542.1 - 0.0011 19.5 0.0 0.0034 17.9 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG68542.1 - 0.0029 17.4 0.0 0.017 14.9 0.0 2.2 2 1 0 2 2 2 1 Aspartyl protease Phage_GPO PF05929.11 GBG68542.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Chromo PF00385.24 GBG68543.1 - 1.8e-11 43.8 0.0 3.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG68546.1 - 3.7e-37 128.0 0.0 6.2e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG68546.1 - 7.2e-06 26.6 0.4 7.2e-06 26.6 0.4 2.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase ABC_tran PF00005.27 GBG68547.1 - 3.3e-08 34.1 0.0 6.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GBG68547.1 - 5.1e-05 22.8 0.1 7.2e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 GBG68548.1 - 7.4e-12 45.5 0.1 8.4e-12 45.3 0.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region RVT_1 PF00078.27 GBG68549.1 - 5.1e-31 107.9 0.1 9.2e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68549.1 - 1.3e-29 102.1 0.1 2.7e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68549.1 - 1.9e-26 92.4 0.1 4.5e-26 91.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68549.1 - 3e-19 68.9 0.1 7.6e-19 67.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68549.1 - 2.6e-14 53.5 0.0 8.7e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG68549.1 - 0.022 15.0 0.5 0.22 11.8 0.0 2.8 3 0 0 3 3 3 0 H2C2 zinc finger Chromo PF00385.24 GBG68549.1 - 0.051 13.5 0.1 0.74 9.8 0.0 2.6 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 GBG68549.1 - 0.074 12.8 0.0 0.29 11.0 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain DUF659 PF04937.15 GBG68551.1 - 1.2e-19 70.6 0.0 5.6e-19 68.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Secretin_N_2 PF07655.13 GBG68552.1 - 0.014 15.9 4.8 0.014 15.9 4.8 4.4 2 1 2 4 4 4 0 Secretin N-terminal domain TCP PF03634.13 GBG68552.1 - 8.7 6.9 13.7 4.6 7.8 7.9 2.3 2 0 0 2 2 2 0 TCP family transcription factor zf-CCHC PF00098.23 GBG68553.1 - 9e-06 25.5 3.8 1.4e-05 24.9 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle Amidohydro_1 PF01979.20 GBG68553.1 - 0.083 12.2 1.3 0.12 11.6 1.3 1.3 1 1 0 1 1 1 0 Amidohydrolase family PRIMA1 PF16101.5 GBG68553.1 - 0.096 12.7 2.1 0.19 11.8 2.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3037 PF11236.8 GBG68553.1 - 0.87 10.0 5.2 16 6.0 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) DUF305 PF03713.13 GBG68553.1 - 1.1 9.3 8.5 3.1 7.9 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF305) VIR_N PF15912.5 GBG68553.1 - 1.6 8.3 6.9 0.48 10.0 3.9 1.6 1 1 1 2 2 2 0 Virilizer, N-terminal XhlA PF10779.9 GBG68553.1 - 3 8.1 10.5 0.25 11.5 3.2 2.8 3 1 1 4 4 4 0 Haemolysin XhlA RmuC PF02646.16 GBG68553.1 - 3.3 6.8 15.0 1.5 7.8 4.2 2.1 2 0 0 2 2 2 0 RmuC family RT_RNaseH_2 PF17919.1 GBG68554.1 - 4.5e-35 119.7 0.0 7.7e-35 118.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68554.1 - 9.3e-22 77.3 0.0 1.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68554.1 - 3.4e-08 33.3 0.1 4.9e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG68555.1 - 5.8e-07 29.3 1.8 9.7e-07 28.6 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle CP12 PF02672.15 GBG68555.1 - 0.057 14.2 0.1 0.057 14.2 0.1 3.2 3 0 0 3 3 3 0 CP12 domain Holin_BhlA PF10960.8 GBG68555.1 - 5.9 6.9 8.2 2.4 8.2 3.3 2.7 2 0 0 2 2 2 0 BhlA holin family Peptidase_M29 PF02073.15 GBG68556.1 - 0.0011 17.8 5.2 0.0014 17.5 5.2 1.1 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) Retrotrans_gag PF03732.17 GBG68556.1 - 0.36 11.1 10.2 6.8 7.0 0.1 3.6 2 2 0 3 3 3 0 Retrotransposon gag protein DivIC PF04977.15 GBG68556.1 - 0.38 10.6 5.7 4.3 7.2 0.1 3.3 3 0 0 3 3 3 0 Septum formation initiator SlyX PF04102.12 GBG68556.1 - 0.57 10.8 15.9 3.1 8.5 0.2 3.5 3 1 0 3 3 3 0 SlyX FAM76 PF16046.5 GBG68556.1 - 0.95 8.8 4.0 1.2 8.4 4.0 1.1 1 0 0 1 1 1 0 FAM76 protein Phage_GP20 PF06810.11 GBG68558.1 - 0.042 13.7 12.6 0.082 12.7 12.6 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 WEMBL PF05701.11 GBG68558.1 - 0.13 10.9 31.3 2.5 6.7 31.2 2.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light GLE1 PF07817.13 GBG68558.1 - 0.18 11.0 5.3 0.62 9.2 4.6 2.0 1 1 1 2 2 2 0 GLE1-like protein LMBR1 PF04791.16 GBG68558.1 - 1.5 7.6 5.0 2.6 6.9 5.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5082 PF16888.5 GBG68558.1 - 2.2 8.6 17.4 0.09 13.1 10.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Macoilin PF09726.9 GBG68558.1 - 3.3 6.1 31.3 0.018 13.6 15.0 2.1 2 0 0 2 2 2 0 Macoilin family TPPK_C PF12555.8 GBG68559.1 - 0.0087 16.1 5.6 0.022 14.8 5.6 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal DDE_Tnp_4 PF13359.6 GBG68560.1 - 3.9e-12 46.1 0.0 7.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68560.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein UPF0730 PF15827.5 GBG68560.1 - 0.068 12.9 0.3 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 UPF0730 unknown protein family rve PF00665.26 GBG68561.1 - 0.0004 20.6 0.0 0.00087 19.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG68561.1 - 0.1 12.9 0.3 0.1 12.9 0.3 2.7 2 1 0 2 2 2 0 Retrotransposon gag protein FAM75 PF14650.6 GBG68562.1 - 0.98 8.9 7.7 1.3 8.5 7.7 1.1 1 0 0 1 1 1 0 FAM75 family DUF4769 PF15992.5 GBG68562.1 - 7.9 6.2 6.5 12 5.6 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) zf-CCHC PF00098.23 GBG68563.1 - 1.3e-05 25.0 2.4 2.2e-05 24.3 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG68563.1 - 0.00022 21.0 7.6 0.00035 20.3 7.6 1.3 1 0 0 1 1 1 1 Zinc knuckle AAA_23 PF13476.6 GBG68563.1 - 1.8 9.0 13.4 0.18 12.3 7.8 1.9 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.12 GBG68566.1 - 0.047 11.9 13.9 0.058 11.6 13.9 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG68566.1 - 0.71 9.2 17.0 0.91 8.9 17.0 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG68566.1 - 1.2 7.8 6.0 1.7 7.3 6.0 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG68566.1 - 1.7 6.8 14.1 2.2 6.5 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG68566.1 - 1.9 8.3 9.3 2.7 7.7 9.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PfkB PF00294.24 GBG68568.1 - 1.3e-32 113.3 0.0 3.7e-32 111.8 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 GBG68568.1 - 0.0037 16.7 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ETRAMP PF09716.10 GBG68570.1 - 0.77 9.9 3.7 4.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RT_RNaseH_2 PF17919.1 GBG68571.1 - 2e-25 88.7 0.0 4.2e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68571.1 - 2.5e-25 88.8 0.0 4.7e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG68571.1 - 0.042 14.1 0.1 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Actin PF00022.19 GBG68572.1 - 3e-32 111.7 0.0 4.2e-18 65.2 0.0 3.1 1 1 2 3 3 3 3 Actin F-box-like PF12937.7 GBG68572.1 - 3.8e-10 39.5 0.1 1.1e-09 38.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG68572.1 - 8.8e-05 22.3 0.9 0.00023 20.9 0.9 1.7 1 0 0 1 1 1 1 F-box domain Zn-ribbon_8 PF09723.10 GBG68573.1 - 0.035 14.2 4.1 0.57 10.3 2.4 2.9 2 0 0 2 2 2 0 Zinc ribbon domain zf-IS66 PF13005.7 GBG68573.1 - 1.7 9.1 0.0 1.7 9.1 0.0 3.6 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 JmjC PF02373.22 GBG68574.1 - 9.1e-15 55.1 0.1 9.1e-15 55.1 0.1 3.7 3 1 0 3 3 3 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 GBG68574.1 - 0.0016 18.7 16.2 0.0016 18.7 16.2 3.3 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 AT_hook PF02178.19 GBG68574.1 - 6.9 6.9 87.7 9.7 6.4 7.6 10.4 9 0 0 9 9 9 0 AT hook motif RVT_1 PF00078.27 GBG68575.1 - 7.7e-27 94.2 0.0 1.3e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG68575.1 - 6.2e-06 26.8 0.0 1.6e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68575.1 - 0.00021 21.8 0.0 0.00048 20.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG68575.1 - 0.00066 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG68575.1 - 0.004 16.9 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG68575.1 - 0.0067 16.7 1.2 0.027 14.7 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Aminotran_1_2 PF00155.21 GBG68577.1 - 7.5e-39 133.9 0.0 1.1e-38 133.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF5594 PF18057.1 GBG68577.1 - 0.034 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5594) CLTH PF10607.9 GBG68578.1 - 9.4e-36 122.9 0.4 1.3e-35 122.5 0.4 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GBG68578.1 - 2e-10 40.2 0.2 6e-10 38.7 0.1 1.9 2 0 0 2 2 2 1 LisH TINF2_N PF14973.6 GBG68578.1 - 0.0071 16.7 1.9 0.072 13.4 0.2 2.3 2 0 0 2 2 2 1 TERF1-interacting nuclear factor 2 N-terminus ERM PF00769.19 GBG68578.1 - 0.3 10.9 8.0 0.093 12.5 5.4 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Rad1 PF02144.16 GBG68579.1 - 1.6e-20 73.3 0.0 3e-20 72.4 0.0 1.5 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 gag-asp_proteas PF13975.6 GBG68580.1 - 5.5e-07 30.1 0.1 1.2e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68580.1 - 0.00042 20.9 0.1 0.00096 19.7 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68580.1 - 0.00097 18.9 0.2 0.0015 18.3 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG68580.1 - 0.0048 16.5 0.2 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 Topoisomerase I zinc-ribbon-like RVP_2 PF08284.11 GBG68580.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG68581.1 - 0.048 13.8 1.9 0.1 12.7 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle ATE_N PF04376.13 GBG68581.1 - 0.066 13.6 0.1 0.96 9.9 0.0 2.6 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus MULE PF10551.9 GBG68582.1 - 3.3e-17 62.7 0.0 5.9e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG68582.1 - 1.5e-11 44.1 0.1 4.1e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 MuDR family transposase SWIM PF04434.17 GBG68582.1 - 5.7e-05 22.7 0.1 0.00014 21.5 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger GAS PF13851.6 GBG68583.1 - 0.5 9.7 24.5 0.049 13.0 13.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding LAP1C PF05609.12 GBG68583.1 - 2.4 7.1 14.9 3 6.8 14.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) HHH_6 PF14579.6 GBG68583.1 - 4 7.8 6.8 0.53 10.6 0.3 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Speriolin_N PF15058.6 GBG68583.1 - 9.3 6.3 8.9 1.2 9.2 0.8 2.2 2 0 0 2 2 2 0 Speriolin N terminus TBPIP PF07106.13 GBG68585.1 - 9.5e-23 79.9 1.2 9.5e-23 79.9 1.2 1.8 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 GBG68585.1 - 1.6e-14 53.7 3.8 1.6e-14 53.7 3.8 2.8 3 0 0 3 3 3 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 GBG68585.1 - 9.1e-08 32.5 0.8 1.7e-07 31.6 0.7 1.6 1 1 0 1 1 1 1 Penicillinase repressor TFIIE_beta PF02186.15 GBG68585.1 - 0.002 18.3 3.4 0.24 11.7 0.2 2.5 2 0 0 2 2 2 1 TFIIE beta subunit core domain PilJ PF13675.6 GBG68585.1 - 0.0057 16.7 1.6 0.022 14.8 0.3 2.2 1 1 1 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term MethyTransf_Reg PF10119.9 GBG68585.1 - 0.023 15.4 0.0 0.068 13.9 0.0 1.8 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain TrmB PF01978.19 GBG68585.1 - 0.035 14.0 0.2 0.16 11.9 0.0 2.1 3 0 0 3 3 2 0 Sugar-specific transcriptional regulator TrmB DUF4988 PF16378.5 GBG68585.1 - 0.054 13.2 3.3 0.099 12.3 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function Mnd1 PF03962.15 GBG68585.1 - 0.068 13.5 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Mnd1 HTH domain CCM2_C PF16545.5 GBG68585.1 - 0.076 13.6 1.2 0.71 10.4 0.3 2.7 2 1 0 2 2 1 0 Cerebral cavernous malformation protein, harmonin-homology Fib_alpha PF08702.10 GBG68585.1 - 0.45 10.7 10.2 0.26 11.4 6.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IclR PF01614.18 GBG68585.1 - 0.49 10.2 3.6 2 8.3 1.7 2.6 2 1 1 3 3 3 0 Bacterial transcriptional regulator FlaC_arch PF05377.11 GBG68585.1 - 0.51 10.8 0.1 0.51 10.8 0.1 2.9 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Rootletin PF15035.6 GBG68585.1 - 0.6 10.1 10.0 0.11 12.5 3.1 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.21 GBG68585.1 - 0.73 10.0 12.4 2.2 8.4 2.6 3.2 2 1 0 3 3 3 0 bZIP transcription factor DivIC PF04977.15 GBG68585.1 - 0.81 9.5 13.9 2.7 7.8 0.1 3.1 2 1 1 3 3 3 0 Septum formation initiator ZapB PF06005.12 GBG68585.1 - 0.89 10.0 13.0 3.6 8.1 7.8 3.0 2 1 0 2 2 2 0 Cell division protein ZapB TMCO5 PF14992.6 GBG68585.1 - 1.3 8.6 12.5 1.6 8.3 12.5 1.2 1 0 0 1 1 1 0 TMCO5 family YabA PF06156.13 GBG68585.1 - 1.4 9.6 11.5 0.14 12.8 4.3 2.7 1 1 3 4 4 4 0 Initiation control protein YabA Uso1_p115_C PF04871.13 GBG68585.1 - 1.4 9.3 12.8 0.51 10.7 9.8 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ABC_tran_CTD PF16326.5 GBG68585.1 - 2.5 8.4 13.6 0.12 12.6 5.2 2.7 2 1 0 3 3 3 0 ABC transporter C-terminal domain FmdE PF02663.14 GBG68585.1 - 2.6 8.1 6.1 14 5.7 6.1 2.1 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon FliJ PF02050.16 GBG68585.1 - 2.7 8.2 15.7 0.042 14.1 4.4 2.4 2 1 1 3 3 2 0 Flagellar FliJ protein DUF1664 PF07889.12 GBG68585.1 - 6 6.9 8.8 0.58 10.2 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 GBG68585.1 - 7.4 7.1 14.1 6.9 7.2 11.8 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4795 PF16043.5 GBG68585.1 - 8 6.0 19.0 30 4.1 12.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Ant_C PF05586.11 GBG68586.1 - 0.026 15.1 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 Anthrax receptor C-terminus region RVT_1 PF00078.27 GBG68587.1 - 5e-29 101.4 0.1 7.8e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG68587.1 - 4.3e-12 45.7 0.0 8.3e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG68587.1 - 7e-07 29.4 0.2 2.5e-06 27.7 0.1 1.9 1 1 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG68588.1 - 3.7e-29 100.7 0.0 1e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68588.1 - 2.7e-27 95.1 0.0 6.1e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68588.1 - 6.1e-08 32.5 0.1 9.6e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG68588.1 - 0.45 10.8 9.9 0.74 10.1 9.9 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG68588.1 - 2 6.5 21.7 3.1 5.9 21.7 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG68588.1 - 8.6 5.7 24.9 12 5.2 24.9 1.1 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG68589.1 - 0.49 10.6 10.5 0.8 9.9 10.5 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG68589.1 - 1.4 7.1 21.7 2.2 6.4 21.7 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG68589.1 - 5 6.4 24.0 7 5.9 24.0 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG68589.1 - 6.4 6.1 24.9 8.7 5.7 24.9 1.1 1 0 0 1 1 1 0 SDA1 DUF4746 PF15928.5 GBG68589.1 - 6.5 6.1 13.1 9.4 5.6 13.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 GBG68589.1 - 7.9 4.6 15.8 13 3.9 15.8 1.3 1 0 0 1 1 1 0 CDC45-like protein HEAT PF02985.22 GBG68591.1 - 1.3e-19 68.6 15.9 0.00013 22.0 0.0 11.0 12 0 0 12 12 11 5 HEAT repeat HEAT_EZ PF13513.6 GBG68591.1 - 6.6e-16 58.4 21.8 5.9e-08 33.0 0.2 10.5 11 2 1 12 12 10 3 HEAT-like repeat HEAT_2 PF13646.6 GBG68591.1 - 2.4e-15 56.7 11.8 7.2e-05 23.1 0.0 7.6 4 3 4 9 9 9 5 HEAT repeats IBN_N PF03810.19 GBG68591.1 - 4.1e-11 42.6 0.1 2.7e-10 40.0 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain ParcG PF10274.9 GBG68591.1 - 6.8e-08 32.8 0.2 0.021 15.0 0.0 4.6 4 1 2 6 6 6 2 Parkin co-regulated protein DUF3385 PF11865.8 GBG68591.1 - 4.6e-06 26.6 0.0 0.089 12.7 0.0 6.4 7 2 2 9 9 9 1 Domain of unknown function (DUF3385) DUF4042 PF13251.6 GBG68591.1 - 1.3e-05 25.0 1.4 0.0052 16.5 0.1 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4042) Cnd1 PF12717.7 GBG68591.1 - 0.00022 21.3 0.0 0.017 15.2 0.0 3.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 GBG68591.1 - 0.00026 20.2 4.3 3.8 6.5 0.0 5.4 5 2 2 7 7 7 2 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 GBG68591.1 - 0.00074 19.2 0.0 16 5.0 0.0 5.2 4 2 1 5 5 5 0 CLASP N terminal RIX1 PF08167.12 GBG68591.1 - 0.001 18.9 0.0 4.8 6.9 0.0 4.2 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 GBG68591.1 - 0.0011 19.0 0.0 0.1 12.7 0.0 3.1 1 1 0 1 1 1 1 Exportin 1-like protein Vac14_Fab1_bd PF12755.7 GBG68591.1 - 0.0014 19.2 0.0 2.8 8.6 0.0 5.4 5 1 0 6 6 5 1 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 GBG68591.1 - 0.0073 15.5 0.2 0.1 11.7 0.1 2.5 2 0 0 2 2 2 1 Dopey, N-terminal Importin_rep_4 PF18808.1 GBG68591.1 - 0.0083 16.4 0.6 0.54 10.6 0.0 3.6 3 0 0 3 3 3 1 Importin repeat MMS19_C PF12460.8 GBG68591.1 - 0.12 11.4 0.0 17 4.3 0.0 2.9 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal PFK PF00365.20 GBG68592.1 - 3.7e-34 118.3 0.0 4.7e-33 114.7 0.0 2.0 1 1 0 1 1 1 1 Phosphofructokinase OmpA_like PF16961.5 GBG68592.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative OmpA-OmpF-like porin family PFK PF00365.20 GBG68593.1 - 1.2e-34 119.9 0.0 1.5e-33 116.3 0.0 2.0 1 1 0 1 1 1 1 Phosphofructokinase OmpA_like PF16961.5 GBG68593.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative OmpA-OmpF-like porin family PAP_fibrillin PF04755.12 GBG68594.1 - 1.3e-31 110.1 0.9 2.1e-20 73.5 0.1 2.2 1 1 1 2 2 2 2 PAP_fibrillin PAP_fibrillin PF04755.12 GBG68595.1 - 2.9e-17 63.3 2.2 2.3e-09 37.5 0.3 3.2 2 1 0 2 2 2 2 PAP_fibrillin gag-asp_proteas PF13975.6 GBG68596.1 - 7.7e-08 32.8 0.1 1.8e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68596.1 - 5.4e-06 27.0 0.1 1.2e-05 25.8 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68596.1 - 0.002 17.9 0.1 0.0043 16.9 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG68596.1 - 0.006 16.1 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG68596.1 - 0.043 13.6 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG68597.1 - 3e-05 24.3 1.6 0.0001 22.6 0.6 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF3361 PF11841.8 GBG68598.1 - 0.00013 22.0 0.2 0.08 12.9 0.0 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF3361) HEAT_2 PF13646.6 GBG68598.1 - 0.0035 17.7 6.0 0.075 13.4 0.1 4.5 1 1 3 4 4 4 2 HEAT repeats Arm PF00514.23 GBG68598.1 - 0.081 13.0 8.5 0.49 10.5 0.7 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GBG68598.1 - 0.83 10.1 5.5 0.25 11.7 0.4 2.9 4 0 0 4 4 4 0 HEAT repeat Helicase_C PF00271.31 GBG68599.1 - 3.3e-13 50.0 0.0 6.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GBG68599.1 - 4.7e-13 49.3 0.0 8.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GBG68599.1 - 0.025 13.8 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SPX PF03105.19 GBG68599.1 - 2.9 7.7 10.1 8.3 6.2 10.3 1.6 1 1 0 1 1 1 0 SPX domain DEAD PF00270.29 GBG68600.1 - 2.6e-14 53.4 0.0 4.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG68600.1 - 3.2e-13 50.0 0.0 6.8e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GBG68600.1 - 0.027 13.7 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Apt1 PF10351.9 GBG68600.1 - 1.3 7.8 5.0 0.27 10.1 0.3 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF287 PF03384.14 GBG68601.1 - 0.48 10.8 4.0 0.31 11.5 0.6 2.3 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 DUF1295 PF06966.12 GBG68602.1 - 2.1e-58 197.6 11.3 3e-58 197.1 11.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 GBG68602.1 - 0.0033 17.8 5.3 0.0088 16.4 0.0 3.1 2 1 1 3 3 3 1 Phospholipid methyltransferase Steroid_dh PF02544.16 GBG68602.1 - 0.008 16.2 1.0 0.008 16.2 1.0 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 GBG68602.1 - 0.014 15.7 0.9 0.058 13.8 0.0 2.5 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TPT PF03151.16 GBG68602.1 - 0.058 12.7 2.0 5.5 6.2 0.4 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family Chordopox_A20R PF05941.13 GBG68602.1 - 0.25 10.3 0.0 0.25 10.3 0.0 1.5 2 0 0 2 2 2 0 Chordopoxvirus A20R protein tRNA-synt_1d PF00750.19 GBG68603.1 - 3.6e-116 387.9 0.7 2.8e-89 299.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 GBG68603.1 - 1.2e-29 102.9 0.0 4e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 GBG68603.1 - 1.1e-18 67.5 0.0 1e-17 64.5 0.2 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain FancD2 PF14631.6 GBG68604.1 - 1.1e-141 473.8 0.0 1.6e-141 473.3 0.0 1.2 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 GBG68604.1 - 0.00063 20.1 0.1 0.098 13.0 0.0 2.9 2 0 0 2 2 2 2 FANCI solenoid 2 FancD2 PF14631.6 GBG68605.1 - 9.5e-91 305.0 0.0 1.2e-90 304.6 0.0 1.1 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 GBG68605.1 - 0.13 12.6 1.0 23 5.3 0.1 2.9 2 1 0 3 3 3 0 FANCI solenoid 2 DUF4777 PF16007.5 GBG68605.1 - 0.14 12.4 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) FancD2 PF14631.6 GBG68606.1 - 1.1e-39 135.8 0.0 2.1e-39 134.9 0.0 1.4 1 1 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease RVT_1 PF00078.27 GBG68607.1 - 2.7e-36 125.2 0.0 4.7e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68607.1 - 4.9e-30 103.5 0.0 1.5e-29 102.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68607.1 - 9e-30 103.1 0.0 2.1e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase 2OG-FeII_Oxy_2 PF13532.6 GBG68607.1 - 0.051 13.8 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Phage_GPO PF05929.11 GBG68607.1 - 0.91 9.1 3.9 0.41 10.2 0.1 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase YccV-like PF08755.11 GBG68609.1 - 4.7e-14 52.7 0.0 8.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like DUF5549 PF17703.1 GBG68609.1 - 0.0097 15.6 0.6 0.016 14.8 0.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5549) Phage_glycop_gL PF11108.8 GBG68609.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Viral glycoprotein L DDE_Tnp_4 PF13359.6 GBG68611.1 - 0.048 13.3 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease SbmA_BacA PF05992.12 GBG68613.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 SbmA/BacA-like family Acyl-CoA_dh_2 PF08028.11 GBG68613.1 - 0.096 13.0 0.0 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain RVT_1 PF00078.27 GBG68614.1 - 5.9e-11 42.3 0.0 1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG68614.1 - 9.6e-07 28.6 0.0 2.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68614.1 - 4.2e-05 24.1 0.0 0.00018 22.1 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68614.1 - 0.00094 19.0 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68614.1 - 0.0023 18.5 0.0 0.009 16.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease HALZ PF02183.18 GBG68614.1 - 0.0045 17.2 1.7 0.012 15.8 1.7 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 GBG68614.1 - 0.0063 16.6 2.0 0.02 15.0 2.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor FlaC_arch PF05377.11 GBG68614.1 - 0.036 14.4 1.3 0.27 11.6 1.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fascin PF06268.13 GBG68614.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Fascin domain DivIC PF04977.15 GBG68614.1 - 0.061 13.1 2.5 0.23 11.3 2.5 1.9 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 GBG68614.1 - 0.074 13.1 3.9 0.21 11.7 3.9 1.8 1 0 0 1 1 1 0 Basic region leucine zipper ZapB PF06005.12 GBG68614.1 - 0.16 12.5 4.5 0.5 10.9 3.4 2.4 2 0 0 2 2 2 0 Cell division protein ZapB TSC22 PF01166.18 GBG68614.1 - 0.49 10.7 3.8 1.7 9.0 0.9 2.7 3 0 0 3 3 2 0 TSC-22/dip/bun family Rhodanese PF00581.20 GBG68615.1 - 1.3e-11 44.9 0.0 1.5e-10 41.6 0.0 2.1 1 1 0 1 1 1 1 Rhodanese-like domain Hydrolase_4 PF12146.8 GBG68616.1 - 6.5e-10 38.7 0.0 0.00066 19.0 0.0 3.3 3 0 0 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG68616.1 - 1.6e-06 28.0 0.1 0.014 15.1 0.0 3.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG68616.1 - 3e-06 28.0 9.1 6.2e-06 27.0 2.0 2.9 3 1 0 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GBG68616.1 - 0.00016 21.5 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.21 GBG68616.1 - 0.0089 15.5 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 GBG68616.1 - 0.036 13.6 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Siva PF05458.12 GBG68617.1 - 0.013 15.2 1.1 3.6 7.2 0.1 2.2 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Pox_TAA1 PF03295.14 GBG68617.1 - 0.039 13.8 2.6 5.8 6.9 0.2 2.8 2 2 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal AAA_assoc PF14363.6 GBG68617.1 - 0.068 13.5 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA SlpA PF03217.14 GBG68617.1 - 0.1 13.2 1.4 6.9 7.4 0.2 2.4 2 0 0 2 2 2 0 Surface later protein A domain DUF4366 PF14283.6 GBG68618.1 - 1 9.4 20.2 0.19 11.7 3.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) IBR PF01485.21 GBG68619.1 - 1.4e-17 63.7 41.1 1.8e-11 44.1 6.5 4.1 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 GBG68619.1 - 0.00092 19.0 5.6 0.00092 19.0 5.6 6.3 5 2 2 7 7 7 3 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG68619.1 - 0.00098 19.0 4.9 0.00098 19.0 4.9 4.2 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 GBG68619.1 - 0.0037 17.6 5.8 0.0037 17.6 5.8 4.8 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 GBG68619.1 - 0.0064 16.3 6.2 0.0064 16.3 6.2 5.3 5 2 2 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG68619.1 - 0.0072 16.3 1.6 0.0072 16.3 1.6 5.1 4 1 1 5 5 5 2 RING-type zinc-finger CDC45 PF02724.14 GBG68620.1 - 0.013 13.8 3.6 0.017 13.4 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG68620.1 - 0.016 14.0 0.2 0.018 13.9 0.2 1.1 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 GBG68620.1 - 0.019 14.4 1.1 0.024 14.1 1.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4366 PF14283.6 GBG68620.1 - 0.21 11.6 2.0 0.37 10.8 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Nop14 PF04147.12 GBG68620.1 - 0.25 9.5 9.9 0.31 9.2 9.9 1.0 1 0 0 1 1 1 0 Nop14-like family Plasmodium_Vir PF05795.11 GBG68620.1 - 0.37 10.1 2.7 0.44 9.9 2.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Eapp_C PF10238.9 GBG68620.1 - 0.82 9.7 4.7 1.3 9.1 4.7 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Tim54 PF11711.8 GBG68620.1 - 1.2 7.9 8.5 1.6 7.5 8.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.10 GBG68620.1 - 1.3 9.1 6.0 2 8.4 6.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NPR3 PF03666.13 GBG68620.1 - 4.4 6.0 6.2 7 5.3 6.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 GBG68620.1 - 4.5 7.0 12.1 6.2 6.6 12.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RT_RNaseH_2 PF17919.1 GBG68621.1 - 4.6e-29 100.4 0.3 8.2e-29 99.6 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68621.1 - 1.5e-26 93.3 0.1 2.1e-26 92.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68621.1 - 1.9e-17 63.4 0.1 4e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5095 PF17016.5 GBG68621.1 - 0.12 12.1 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) CDC45 PF02724.14 GBG68623.1 - 0.95 7.7 8.0 1.1 7.5 8.0 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG68623.1 - 4 6.8 12.5 4.4 6.6 12.5 1.1 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 GBG68623.1 - 5.7 6.9 22.8 8.3 6.4 22.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.12 GBG68623.1 - 7 4.7 12.6 8 4.5 12.6 1.0 1 0 0 1 1 1 0 Nop14-like family DNase-RNase PF02577.14 GBG68624.1 - 1.9e-19 69.6 0.0 3.2e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.19 GBG68624.1 - 0.0018 17.9 0.8 0.0018 17.9 0.8 1.8 2 0 0 2 2 2 1 UvrB/uvrC motif rve PF00665.26 GBG68625.1 - 1.5e-12 47.7 0.0 3.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG68625.1 - 0.0021 17.8 0.0 0.007 16.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Miga PF10265.9 GBG68625.1 - 0.013 14.5 4.0 0.024 13.6 4.0 1.4 1 0 0 1 1 1 0 Mitoguardin Clr5 PF14420.6 GBG68625.1 - 0.062 13.5 0.8 1.8 8.9 0.3 3.0 3 0 0 3 3 3 0 Clr5 domain Peptidase_S64 PF08192.11 GBG68625.1 - 0.069 11.6 1.2 0.091 11.2 0.9 1.4 1 1 0 1 1 1 0 Peptidase family S64 SR-25 PF10500.9 GBG68625.1 - 0.68 9.5 19.4 0.042 13.4 4.0 2.4 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 GBG68625.1 - 1.8 6.7 5.5 2.6 6.2 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Tmemb_cc2 PF10267.9 GBG68625.1 - 3.5 6.7 12.0 0.017 14.3 2.0 2.1 3 0 0 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein PTH2 PF01981.16 GBG68626.1 - 1.1e-18 67.6 0.6 1.7e-18 67.0 0.6 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Ribonucleas_3_3 PF14622.6 GBG68626.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 2 0 0 2 2 2 0 Ribonuclease-III-like zf-Tim10_DDP PF02953.15 GBG68627.1 - 6e-19 67.5 0.4 7e-19 67.2 0.4 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger gag-asp_proteas PF13975.6 GBG68628.1 - 2.6e-07 31.1 0.0 6.1e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68628.1 - 5.7e-05 23.7 0.0 0.00013 22.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68628.1 - 0.00053 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG68628.1 - 0.0068 16.2 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease MRP-S33 PF08293.11 GBG68629.1 - 8.6 6.7 7.8 21 5.4 1.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit S27 GrpE PF01025.19 GBG68630.1 - 7.3e-43 146.1 0.6 1.1e-42 145.5 0.6 1.2 1 0 0 1 1 1 1 GrpE DUF1456 PF07308.13 GBG68630.1 - 0.026 14.8 0.1 8.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) RT_RNaseH PF17917.1 GBG68631.1 - 3.6e-24 85.0 0.0 1.5e-23 83.1 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68631.1 - 1.4e-23 82.8 0.0 5.6e-23 80.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG68631.1 - 0.032 14.5 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein WTX PF09422.10 GBG68631.1 - 0.092 11.8 0.6 0.2 10.7 0.6 1.4 1 0 0 1 1 1 0 WTX protein Pan_kinase PF03309.14 GBG68631.1 - 0.11 12.3 0.5 0.21 11.4 0.5 1.5 1 0 0 1 1 1 0 Type III pantothenate kinase SlyX PF04102.12 GBG68631.1 - 0.11 13.1 0.5 0.11 13.1 0.5 3.5 4 0 0 4 4 4 0 SlyX DNA_methylase PF00145.17 GBG68632.1 - 4.1e-30 105.3 0.0 2.2e-21 76.5 0.0 2.7 3 0 0 3 3 3 2 C-5 cytosine-specific DNA methylase DUF4042 PF13251.6 GBG68634.1 - 7.9e-36 123.5 0.2 7.9e-36 123.5 0.2 4.8 4 1 2 6 6 6 1 Domain of unknown function (DUF4042) HEAT PF02985.22 GBG68634.1 - 1.4e-12 46.7 16.6 0.005 17.0 0.1 8.3 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 GBG68634.1 - 1e-09 38.7 8.3 0.046 14.1 0.0 7.0 3 1 3 7 7 7 5 HEAT repeats HEAT_EZ PF13513.6 GBG68634.1 - 2.7e-07 31.0 11.8 5.6 7.6 0.2 7.2 6 0 0 6 6 6 2 HEAT-like repeat Cnd1 PF12717.7 GBG68634.1 - 0.0027 17.8 0.4 3.7 7.6 0.0 3.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 GBG68634.1 - 0.0041 17.4 0.8 0.98 9.8 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 GBG68634.1 - 0.013 15.1 0.2 0.42 10.1 0.0 3.0 2 1 1 3 3 3 0 CLASP N terminal Arm PF00514.23 GBG68634.1 - 0.41 10.8 14.1 9.6 6.4 0.1 5.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat APP_E2 PF12925.7 GBG68635.1 - 0.033 13.9 0.5 0.057 13.1 0.3 1.5 1 1 0 1 1 1 0 E2 domain of amyloid precursor protein ketoacyl-synt PF00109.26 GBG68636.1 - 9.9e-57 192.4 0.2 9.9e-57 192.4 0.2 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GBG68636.1 - 1.4e-33 115.4 0.7 2.9e-33 114.4 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GBG68636.1 - 0.014 14.8 0.1 0.014 14.8 0.1 2.3 3 0 0 3 3 3 0 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 GBG68636.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension TRPM_tetra PF16519.5 GBG68638.1 - 0.28 11.3 2.3 3.6 7.8 0.1 3.0 2 1 0 2 2 2 0 Tetramerisation domain of TRPM SlyX PF04102.12 GBG68638.1 - 1.6 9.4 16.4 0.14 12.8 0.7 3.9 4 0 0 4 4 4 0 SlyX FAM76 PF16046.5 GBG68638.1 - 2.3 7.5 8.2 3.2 7.0 8.2 1.2 1 0 0 1 1 1 0 FAM76 protein Draxin PF15550.6 GBG68638.1 - 2.4 7.9 9.7 1.4 8.7 8.0 1.4 1 1 0 1 1 1 0 Draxin Aconitase_C PF00694.19 GBG68639.1 - 0.0053 17.1 1.4 14 6.0 0.0 3.4 3 0 0 3 3 3 1 Aconitase C-terminal domain RHH_4 PF13467.6 GBG68639.1 - 0.011 15.6 0.0 9.7 6.2 0.0 2.9 2 0 0 2 2 2 0 Ribbon-helix-helix domain DUF5499 PF17603.2 GBG68639.1 - 0.016 15.8 0.8 15 6.3 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5499) HTH_23 PF13384.6 GBG68639.1 - 0.029 14.2 0.0 14 5.6 0.0 3.0 2 0 0 2 2 2 0 Homeodomain-like domain AdoMet_Synthase PF01941.19 GBG68639.1 - 0.13 11.0 6.3 9.9 4.8 0.1 3.6 4 0 0 4 4 4 0 S-adenosylmethionine synthetase (AdoMet synthetase) Pex16 PF08610.10 GBG68640.1 - 4.7e-61 206.7 0.0 5.3e-30 104.7 0.0 2.2 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) RCDG1 PF15725.5 GBG68640.1 - 0.62 10.5 5.7 2.2 8.8 5.7 1.9 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein FRQ PF09421.10 GBG68641.1 - 0.079 11.0 3.4 0.094 10.7 3.4 1.1 1 0 0 1 1 1 0 Frequency clock protein SDA1 PF05285.12 GBG68641.1 - 0.28 10.6 8.6 0.37 10.2 8.6 1.2 1 0 0 1 1 1 0 SDA1 Gag_p12 PF01141.18 GBG68641.1 - 6.3 7.2 10.1 5.8 7.3 2.8 2.4 1 1 1 2 2 2 0 Gag polyprotein, inner coat protein p12 CTP_transf_1 PF01148.20 GBG68643.1 - 2.6e-59 201.2 11.8 3.3e-59 200.8 11.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Atrophin-1 PF03154.15 GBG68644.1 - 0.0024 16.3 7.9 0.0024 16.3 7.9 4.4 3 2 1 4 4 4 1 Atrophin-1 family GCR1_C PF12550.8 GBG68645.1 - 9.6e-13 48.3 2.3 1.8e-12 47.4 2.3 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes COMP PF11598.8 GBG68645.1 - 0.12 12.9 3.2 0.22 12.0 1.7 2.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein NAD_binding_1 PF00175.21 GBG68645.1 - 2.3 8.9 4.8 8.2 7.1 0.4 3.5 2 1 1 3 3 3 0 Oxidoreductase NAD-binding domain AAA PF00004.29 GBG68646.1 - 7e-88 291.8 0.0 1.7e-43 148.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG68646.1 - 1.9e-26 91.6 8.6 1.1e-14 53.9 1.8 2.8 2 0 0 2 2 2 2 AAA+ lid domain RVT_1 PF00078.27 GBG68646.1 - 3.8e-18 65.8 0.0 6.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RuvB_N PF05496.12 GBG68646.1 - 2e-15 56.9 0.0 9.2e-08 32.0 0.0 3.4 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GBG68646.1 - 2.3e-12 47.6 0.1 1.8e-05 25.2 0.0 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 GBG68646.1 - 3.6e-10 40.2 0.0 2.3e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GBG68646.1 - 1.8e-09 37.7 0.0 0.0002 21.4 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GBG68646.1 - 3.6e-08 33.0 0.0 0.0032 16.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 GBG68646.1 - 5.7e-08 33.1 0.0 0.007 16.6 0.0 3.7 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 GBG68646.1 - 1.8e-06 28.2 0.0 0.03 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GBG68646.1 - 7.1e-06 25.5 0.1 0.071 12.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GBG68646.1 - 3.3e-05 24.2 0.0 0.017 15.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 GBG68646.1 - 4.3e-05 23.5 0.0 0.11 12.5 0.0 2.8 2 1 1 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 GBG68646.1 - 8.7e-05 22.3 0.0 0.052 13.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 GBG68646.1 - 0.00019 21.5 0.0 0.041 13.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 GBG68646.1 - 0.00061 20.1 0.0 0.024 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 GBG68646.1 - 0.00063 19.6 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GBG68646.1 - 0.001 18.7 0.9 3 7.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 GBG68646.1 - 0.001 18.6 0.0 0.077 12.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 GBG68646.1 - 0.0027 17.7 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 GBG68646.1 - 0.003 17.5 0.0 0.71 9.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.26 GBG68646.1 - 0.0035 17.0 0.0 0.25 11.0 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 GBG68646.1 - 0.0047 17.5 0.0 0.11 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GBG68646.1 - 0.011 15.6 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 GBG68646.1 - 0.011 14.8 0.0 0.042 12.9 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 GBG68646.1 - 0.014 14.6 0.1 3 7.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 GBG68646.1 - 0.016 14.9 0.0 0.058 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 GBG68646.1 - 0.025 14.7 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 GBG68646.1 - 0.025 13.9 0.0 0.55 9.5 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF815 PF05673.13 GBG68646.1 - 0.032 13.4 0.0 0.32 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 GBG68646.1 - 0.039 13.9 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 GBG68646.1 - 0.04 13.1 0.0 0.71 9.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 GBG68646.1 - 0.089 12.5 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GBG68646.1 - 0.12 11.8 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 GBG68646.1 - 0.17 12.4 0.0 0.95 10.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter PPP4R2 PF09184.11 GBG68647.1 - 0.26 10.9 18.0 0.28 10.7 18.0 1.1 1 0 0 1 1 1 0 PPP4R2 PPR_2 PF13041.6 GBG68648.1 - 4.8e-58 193.2 8.0 9.4e-14 51.3 0.0 9.8 3 2 7 10 10 10 9 PPR repeat family PPR PF01535.20 GBG68648.1 - 4.2e-51 167.7 18.9 3.3e-07 30.1 0.0 10.1 10 0 0 10 10 10 9 PPR repeat PPR_1 PF12854.7 GBG68648.1 - 2.6e-48 161.4 0.2 1.5e-07 31.0 0.0 8.9 9 0 0 9 9 9 8 PPR repeat PPR_3 PF13812.6 GBG68648.1 - 4.7e-45 151.5 0.1 2.6e-13 49.8 0.0 6.2 2 1 2 6 6 6 6 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG68648.1 - 1.7e-22 79.8 1.9 3.6e-09 36.3 0.1 3.9 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 GBG68648.1 - 0.00047 19.3 0.1 0.045 12.9 0.0 3.3 1 1 1 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway MRP-S27 PF10037.9 GBG68648.1 - 0.00078 18.4 0.1 1.2 7.9 0.0 3.4 2 1 0 2 2 2 2 Mitochondrial 28S ribosomal protein S27 Exog_C PF18026.1 GBG68648.1 - 0.19 11.8 0.0 33 4.7 0.0 3.5 3 1 1 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain TPR_14 PF13428.6 GBG68648.1 - 1.2 10.1 12.9 69 4.7 0.0 6.8 5 2 3 8 8 8 0 Tetratricopeptide repeat BTAD PF03704.17 GBG68648.1 - 5.9 7.3 7.1 6.8 7.1 0.1 3.9 4 1 1 5 5 5 0 Bacterial transcriptional activator domain Glyco_transf_8 PF01501.20 GBG68650.1 - 3.4e-53 180.8 0.0 5.4e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GBG68650.1 - 3.1e-05 23.5 0.1 5.7e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 XRN_M PF17846.1 GBG68651.1 - 1.6 7.6 7.2 2.2 7.1 7.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain TPR_14 PF13428.6 GBG68652.1 - 9.6e-09 35.4 23.2 2.3 9.3 0.0 11.0 9 3 2 11 11 11 1 Tetratricopeptide repeat Suf PF05843.14 GBG68652.1 - 4.6e-06 26.8 23.1 0.0021 18.1 0.0 5.6 2 2 4 7 7 7 2 Suppressor of forked protein (Suf) TPR_12 PF13424.6 GBG68652.1 - 2.2e-05 24.7 5.4 4.8 7.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GBG68652.1 - 0.0006 19.8 9.8 3 8.3 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GBG68652.1 - 0.0039 17.2 15.6 2.2 8.3 0.2 7.4 7 1 0 7 7 7 1 Mad3/BUB1 homology region 1 PPR PF01535.20 GBG68652.1 - 0.022 15.0 1.1 0.37 11.1 0.0 3.7 4 0 0 4 4 4 0 PPR repeat TPR_7 PF13176.6 GBG68652.1 - 0.027 14.5 2.2 0.89 9.7 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat HlyD_D4 PF16572.5 GBG68652.1 - 0.033 14.0 0.1 0.097 12.6 0.1 1.7 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB TPR_2 PF07719.17 GBG68652.1 - 0.047 13.8 18.8 3 8.2 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TAF1_subA PF14929.6 GBG68652.1 - 0.33 10.3 3.3 0.39 10.1 1.0 2.1 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A Presenilin PF01080.17 GBG68652.1 - 2.1 7.0 19.6 4.5 5.9 19.6 1.6 1 0 0 1 1 1 0 Presenilin Glyco_transf_8 PF01501.20 GBG68654.1 - 1.4e-77 260.7 0.0 2e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GBG68654.1 - 3e-05 23.6 0.1 5e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 RT_RNaseH_2 PF17919.1 GBG68655.1 - 2.9e-31 107.5 0.0 3.8e-15 55.7 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68655.1 - 2.1e-27 96.1 0.1 3.7e-27 95.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68655.1 - 1.2e-25 89.8 0.0 2.8e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GIY-YIG PF01541.24 GBG68657.1 - 0.00064 19.9 0.0 0.002 18.4 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF2997 PF11211.8 GBG68657.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) MORN PF02493.20 GBG68658.1 - 5.6e-11 41.7 25.9 4.6e-05 23.1 2.5 4.7 4 0 0 4 4 4 3 MORN repeat zf-CCHC PF00098.23 GBG68658.1 - 3.9e-05 23.5 3.1 0.00014 21.8 3.1 2.0 1 0 0 1 1 1 1 Zinc knuckle DUF2781 PF10914.8 GBG68658.1 - 0.00093 19.6 0.1 0.0016 18.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) zf-CCHC_2 PF13696.6 GBG68658.1 - 0.021 14.7 8.1 0.29 11.0 2.5 2.7 2 0 0 2 2 2 0 Zinc knuckle DUF5375 PF17345.2 GBG68658.1 - 0.024 14.5 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5375) DUF3292 PF11696.8 GBG68658.1 - 0.45 8.8 8.4 0.62 8.4 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) BBS1 PF14779.6 GBG68658.1 - 6.5 6.1 5.0 11 5.4 5.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 RT_RNaseH PF17917.1 GBG68659.1 - 5.3e-21 74.9 0.0 9.3e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68659.1 - 1.5e-19 69.9 0.0 2.8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68659.1 - 1.2e-11 44.6 0.1 2.7e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68659.1 - 0.00011 22.3 0.0 0.00028 21.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG68660.1 - 5.7e-07 30.0 0.0 2.2e-06 28.2 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68660.1 - 0.00018 22.1 0.0 0.00057 20.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG68660.1 - 0.0038 17.5 0.1 0.0098 16.2 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG68660.1 - 0.0096 15.7 0.6 0.018 14.8 0.6 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG68660.1 - 0.072 13.4 0.0 0.21 11.9 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG68661.1 - 0.11 12.9 0.4 0.3 11.5 0.4 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain NARP1 PF12569.8 GBG68662.1 - 0.2 10.6 15.3 0.33 9.8 15.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 VSG_B PF13206.6 GBG68662.1 - 1.1 8.4 17.4 0.51 9.5 11.1 2.1 2 0 0 2 2 2 0 Trypanosomal VSG domain GREB1 PF15782.5 GBG68662.1 - 1.7 5.7 12.1 2.3 5.2 12.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2229 PF09989.9 GBG68662.1 - 4.9 6.7 5.5 1.2e+02 2.2 5.9 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Utp14 PF04615.13 GBG68663.1 - 0.5 8.9 18.5 0.63 8.5 18.5 1.1 1 0 0 1 1 1 0 Utp14 protein MORN PF02493.20 GBG68664.1 - 6.4e-06 25.8 7.5 0.04 13.8 1.5 3.7 3 0 0 3 3 3 2 MORN repeat RT_RNaseH_2 PF17919.1 GBG68665.1 - 4e-24 84.5 0.0 7.1e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68665.1 - 1.2e-22 80.1 0.0 2.1e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68665.1 - 2.7e-16 59.4 1.1 5.7e-16 58.4 0.4 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG68665.1 - 7.5e-09 35.4 0.2 1.3e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG68665.1 - 3.1e-05 24.2 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG68665.1 - 0.015 15.5 0.2 0.033 14.4 0.2 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG68666.1 - 3.8e-28 98.2 0.0 7e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68666.1 - 1.2e-14 54.4 0.0 1.7e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68666.1 - 0.0029 17.3 0.2 0.049 13.3 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DAO PF01266.24 GBG68666.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Myb_DNA-bind_4 PF13837.6 GBG68667.1 - 1.4e-07 31.8 1.8 1.4e-07 31.8 1.8 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG68667.1 - 0.003 17.8 3.4 0.008 16.5 0.9 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG68667.1 - 0.087 12.9 1.3 0.17 12.0 1.3 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG68667.1 - 0.12 12.6 0.2 0.26 11.5 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain RVT_1 PF00078.27 GBG68668.1 - 3.1e-26 92.3 0.2 6.1e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG68668.1 - 2.4e-06 28.0 0.0 4.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68668.1 - 8.4e-06 26.3 0.0 1.7e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68668.1 - 3.7e-05 23.5 0.0 7.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG68668.1 - 0.0001 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG68668.1 - 0.038 14.3 0.0 0.15 12.4 0.1 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase ST7 PF04184.12 GBG68668.1 - 0.14 10.6 0.1 0.23 9.9 0.1 1.2 1 0 0 1 1 1 0 ST7 protein Histone PF00125.24 GBG68669.1 - 2.1e-26 92.8 0.5 4.6e-26 91.7 0.5 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Plavaka PF18759.1 GBG68670.1 - 9.2e-19 67.8 0.1 1.6e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase RT_RNaseH PF17917.1 GBG68671.1 - 2.1e-27 95.5 0.0 4e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68671.1 - 1.8e-23 82.4 0.0 1.4e-10 41.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68671.1 - 5e-17 62.2 0.0 7.6e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG68671.1 - 3.5e-16 59.1 0.2 7.5e-16 58.0 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68671.1 - 1.1e-12 48.2 0.5 5.3e-12 46.0 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG68671.1 - 0.00014 22.0 0.1 0.00031 20.9 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Carb_anhydrase PF00194.21 GBG68672.1 - 8.6e-33 113.9 0.0 9.1e-32 110.6 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 GBG68674.1 - 1.3e-32 113.4 0.0 1.3e-31 110.1 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF659 PF04937.15 GBG68678.1 - 5.4e-11 42.6 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) TIR-like PF10137.9 GBG68678.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Carb_anhydrase PF00194.21 GBG68679.1 - 3e-36 125.3 0.0 1.1e-35 123.4 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RVT_1 PF00078.27 GBG68681.1 - 8.2e-31 107.2 0.1 1.3e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG68681.1 - 3.1e-12 46.2 0.0 7.7e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain LMF1 PF06762.14 GBG68681.1 - 0.042 13.0 2.6 0.073 12.2 2.6 1.3 1 0 0 1 1 1 0 Lipase maturation factor TLE_N PF03920.15 GBG68681.1 - 0.2 11.8 0.2 0.4 10.7 0.2 1.4 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain ABC2_membrane PF01061.24 GBG68681.1 - 0.66 9.4 9.3 1.2 8.5 9.3 1.3 1 0 0 1 1 1 0 ABC-2 type transporter Carb_anhydrase PF00194.21 GBG68682.1 - 3.2e-28 99.0 0.0 1.4e-25 90.3 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase zf-C3H1 PF10650.9 GBG68682.1 - 0.048 13.4 0.2 0.089 12.5 0.2 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain DUF3835 PF12927.7 GBG68682.1 - 7.4 7.5 15.5 9.4 7.2 0.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3835) DUF659 PF04937.15 GBG68683.1 - 2.8e-24 85.7 0.0 2.5e-23 82.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) REV1_C PF16727.5 GBG68683.1 - 0.3 11.5 2.3 0.7 10.3 1.3 2.2 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain zf-CCHC PF00098.23 GBG68684.1 - 0.003 17.6 2.0 0.0054 16.8 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG68684.1 - 0.015 14.9 0.3 0.03 14.0 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like rve PF00665.26 GBG68685.1 - 3.8e-15 56.1 0.0 9.9e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG68685.1 - 1.4e-12 47.5 0.0 3.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG68685.1 - 2e-11 43.9 0.0 3.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Angiomotin_C PF12240.8 GBG68685.1 - 0.0044 16.6 0.7 0.015 14.9 0.7 1.9 1 0 0 1 1 1 1 Angiomotin C terminal gag-asp_proteas PF13975.6 GBG68686.1 - 1.5e-07 31.9 0.1 5.5e-07 30.1 0.1 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68686.1 - 5.5e-06 26.9 0.0 2e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68686.1 - 0.00085 19.1 0.1 0.0016 18.2 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68686.1 - 0.03 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG68686.1 - 0.052 13.6 1.9 0.09 12.9 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle FPP PF05911.11 GBG68688.1 - 0.0043 15.3 4.5 0.0055 15.0 4.5 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ADIP PF11559.8 GBG68688.1 - 0.99 9.5 9.2 0.28 11.2 5.4 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.6 GBG68688.1 - 1.1 9.7 8.1 1.2 9.6 4.7 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.8 GBG68688.1 - 2.1 8.6 11.3 0.95 9.7 6.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 GBG68688.1 - 9.6 6.5 10.7 3.7 7.8 3.6 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain gag-asp_proteas PF13975.6 GBG68689.1 - 2.6e-05 24.7 0.0 5.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68689.1 - 0.00082 20.0 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68689.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG68689.1 - 0.037 13.8 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease ATE_N PF04376.13 GBG68689.1 - 0.054 13.9 0.1 0.71 10.3 0.0 2.5 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus Carb_anhydrase PF00194.21 GBG68690.1 - 4.3e-32 111.6 0.0 5e-30 104.9 0.0 2.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Beta_helix PF13229.6 GBG68691.1 - 0.0011 18.8 1.1 0.0038 17.1 1.0 1.9 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG68691.1 - 0.064 13.8 0.0 0.33 11.5 1.7 7.7 8 1 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DDE_Tnp_4 PF13359.6 GBG68692.1 - 1.4e-26 93.1 0.0 1.3e-25 89.9 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68692.1 - 3.9e-12 46.2 0.0 7.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein TrbM PF07424.11 GBG68692.1 - 0.07 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 TrbM DDE_Tnp_1 PF01609.21 GBG68692.1 - 0.12 12.0 0.7 23 4.5 0.0 2.7 3 0 0 3 3 3 0 Transposase DDE domain DUF4149 PF13664.6 GBG68695.1 - 2e-11 44.1 1.3 2e-11 44.1 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Glyco_tranf_2_3 PF13641.6 GBG68695.1 - 0.075 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Chlorosome_CsmC PF11098.8 GBG68695.1 - 1.9 8.5 8.6 3.8 7.5 8.6 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C YtxH PF12732.7 GBG68695.1 - 3.2 8.3 10.5 8.5 7.0 1.5 3.4 2 1 1 3 3 3 0 YtxH-like protein SelR PF01641.18 GBG68696.1 - 8.2e-48 161.5 0.1 1.2e-47 160.9 0.1 1.3 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.6 GBG68696.1 - 0.094 12.8 2.5 0.43 10.7 0.3 2.9 3 1 1 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2457 PF10446.9 GBG68697.1 - 0.013 14.7 18.7 0.013 14.7 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GCIP PF13324.6 GBG68697.1 - 0.018 14.7 4.8 0.02 14.5 4.8 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GBG68697.1 - 0.075 11.1 23.3 0.089 10.9 23.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG68697.1 - 0.077 12.4 13.5 0.081 12.3 13.5 1.0 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG68697.1 - 0.22 10.8 11.9 0.22 10.8 11.9 1.0 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 GBG68697.1 - 0.8 8.6 1.8 0.9 8.5 1.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 GBG68697.1 - 1.4 7.0 18.9 1.5 6.9 18.9 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 GBG68697.1 - 1.7 7.8 9.5 2 7.5 9.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Radial_spoke PF04712.12 GBG68697.1 - 1.9 7.4 7.1 2.2 7.2 7.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.14 GBG68697.1 - 2.6 6.2 14.4 3.2 5.9 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 GBG68697.1 - 2.8 7.7 12.9 3.4 7.4 12.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2722 PF10846.8 GBG68697.1 - 7.8 5.3 9.7 9 5.1 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RVT_1 PF00078.27 GBG68699.1 - 4.1e-08 33.0 0.0 6.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Totivirus_coat PF05518.11 GBG68700.1 - 3.3 5.7 5.4 4.5 5.2 5.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein Branch PF02485.21 GBG68701.1 - 1.9e-47 161.9 0.0 2.9e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Myb_DNA-bind_4 PF13837.6 GBG68702.1 - 1.2e-08 35.3 4.6 1.6e-08 34.8 4.6 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RE_AlwI PF09491.10 GBG68702.1 - 0.044 12.6 0.3 0.052 12.3 0.3 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease RNA_pol_Rpc4 PF05132.14 GBG68703.1 - 0.98 9.8 15.9 1.4 9.3 15.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 VIR_N PF15912.5 GBG68703.1 - 8.4 5.9 22.1 0.88 9.1 16.9 1.8 2 0 0 2 2 2 0 Virilizer, N-terminal RVT_1 PF00078.27 GBG68705.1 - 7.8e-27 94.2 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPAP3_C PF13877.6 GBG68705.1 - 0.065 13.8 0.2 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 DUF1647 PF07801.11 GBG68706.1 - 8.5e-08 32.0 0.0 2.8e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1647) CDC45 PF02724.14 GBG68706.1 - 2.5 6.3 16.2 4.1 5.6 16.2 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC PF00098.23 GBG68707.1 - 6.2e-06 26.1 1.6 1.1e-05 25.3 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle E1_UFD PF09358.10 GBG68707.1 - 0.021 15.5 0.2 0.081 13.6 0.2 2.0 1 0 0 1 1 1 0 Ubiquitin fold domain DUF3911 PF13050.6 GBG68707.1 - 0.14 12.2 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) zf-CCHC_4 PF14392.6 GBG68707.1 - 0.34 10.7 1.1 0.71 9.7 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle LAP1C PF05609.12 GBG68707.1 - 8.2 5.4 15.7 5.2 6.1 14.0 1.5 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RNase_J_C PF17770.1 GBG68708.1 - 2.7 9.1 5.1 0.6 11.2 0.2 2.5 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain NFRKB_winged PF14465.6 GBG68709.1 - 0.0097 16.1 0.0 0.03 14.5 0.0 1.8 1 0 0 1 1 1 1 NFRKB Winged Helix-like Exo_endo_phos_2 PF14529.6 GBG68709.1 - 0.025 14.4 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF1647 PF07801.11 GBG68710.1 - 4.7e-05 23.2 0.0 9.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Secretin_N_2 PF07655.13 GBG68710.1 - 0.03 14.9 1.3 0.079 13.5 0.1 2.4 2 1 0 2 2 2 0 Secretin N-terminal domain TPPK_C PF12555.8 GBG68710.1 - 0.2 11.7 2.5 0.45 10.6 2.5 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal ThrE PF06738.12 GBG68711.1 - 2.4e-41 141.7 28.6 3.4e-37 128.1 7.3 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GBG68711.1 - 2.4e-11 43.9 33.6 2.4e-07 31.0 13.5 2.6 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE Cytochrom_B558a PF05038.13 GBG68711.1 - 0.82 9.2 0.0 0.82 9.2 0.0 3.3 4 0 0 4 4 4 0 Cytochrome Cytochrome b558 alpha-subunit Myb_DNA-bind_4 PF13837.6 GBG68713.1 - 0.0056 17.0 0.6 0.43 11.0 0.2 2.5 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain SDA1 PF05285.12 GBG68714.1 - 7.3 5.9 9.6 9.6 5.5 9.6 1.1 1 0 0 1 1 1 0 SDA1 ERM PF00769.19 GBG68715.1 - 0.0012 18.8 6.9 0.0013 18.6 6.9 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF2080 PF09853.9 GBG68715.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) NICE-3 PF07406.11 GBG68715.1 - 0.11 12.4 1.1 0.18 11.8 0.9 1.4 1 1 0 1 1 1 0 NICE-3 protein RRP36 PF06102.12 GBG68715.1 - 0.43 10.5 8.9 0.58 10.1 8.9 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Glyco_hydro_17 PF00332.18 GBG68717.1 - 1.7e-75 254.5 0.0 1.9e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 GTP_cyclohydro2 PF00925.20 GBG68717.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase II DUF3552 PF12072.8 GBG68718.1 - 0.046 13.1 33.4 0.013 15.0 21.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ARA70 PF12489.8 GBG68718.1 - 1.2 9.3 11.1 4 7.6 3.7 2.4 1 1 0 2 2 2 0 Nuclear coactivator MutL_C PF08676.11 GBG68718.1 - 2 8.2 7.6 1.5 8.6 0.2 2.5 1 1 1 2 2 2 0 MutL C terminal dimerisation domain Glyco_hydro_17 PF00332.18 GBG68719.1 - 1.3e-07 31.6 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Med31 PF05669.12 GBG68721.1 - 1.7e-31 108.1 7.4 5.8e-31 106.3 7.4 2.0 1 0 0 1 1 1 1 SOH1 RT_RNaseH_2 PF17919.1 GBG68721.1 - 1.4e-22 79.5 0.0 3.6e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68721.1 - 8.7e-13 48.5 0.0 2.6e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68721.1 - 0.049 13.1 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) REV PF00424.18 GBG68721.1 - 1.7 8.7 6.6 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) LAP1C PF05609.12 GBG68721.1 - 3.9 6.4 21.0 5.4 6.0 21.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TMEM100 PF16311.5 GBG68721.1 - 5.7 6.5 5.5 14 5.2 3.0 2.5 2 0 0 2 2 2 0 Transmembrane protein 100 RVT_1 PF00078.27 GBG68722.1 - 4.1e-34 118.0 0.0 6.3e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG68722.1 - 2.8e-05 23.9 0.0 6.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68722.1 - 2.8e-05 24.6 0.0 6.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68722.1 - 0.00016 22.2 0.0 0.00043 20.8 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG68722.1 - 0.002 17.9 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) zf-CCHC PF00098.23 GBG68724.1 - 0.028 14.5 1.7 0.063 13.4 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle HAUS6_N PF14661.6 GBG68724.1 - 0.29 10.7 9.5 0.56 9.8 9.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus EIIBC-GUT_N PF03612.14 GBG68724.1 - 0.95 9.2 2.2 1.7 8.4 2.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Exonuc_VII_L PF02601.15 GBG68724.1 - 1.4 8.4 7.0 2.1 7.9 7.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit gag-asp_proteas PF13975.6 GBG68725.1 - 0.00026 21.5 0.6 0.00085 19.8 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68725.1 - 0.0012 19.4 0.2 0.0049 17.5 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease DUF659 PF04937.15 GBG68726.1 - 6.4e-16 58.6 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CDC45 PF02724.14 GBG68726.1 - 7 4.8 9.4 10 4.3 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-bind_4 PF13837.6 GBG68727.1 - 1.6e-08 34.8 7.6 1.7e-07 31.5 4.3 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG68727.1 - 0.0055 17.0 5.8 0.011 16.1 2.7 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like T2SSM PF04612.12 GBG68727.1 - 0.08 13.0 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DDE_Tnp_4 PF13359.6 GBG68728.1 - 1.3e-16 60.7 0.3 5.4e-16 58.7 0.0 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68728.1 - 6.5e-07 29.2 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68728.1 - 0.0025 17.5 0.3 0.0068 16.1 0.0 1.8 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG68729.1 - 7.9e-05 23.0 7.3 0.00012 22.4 1.1 3.2 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG68729.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Orf78 PF06024.12 GBG68729.1 - 0.011 16.1 4.9 1.1 9.5 0.0 3.0 2 0 0 2 2 2 0 Orf78 (ac78) DUF3357 PF11837.8 GBG68729.1 - 0.077 13.5 0.1 0.23 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Fungal_trans_2 PF11951.8 GBG68729.1 - 0.11 11.3 0.8 0.2 10.5 0.8 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF4834 PF16118.5 GBG68729.1 - 1.1 10.3 6.0 8.3 7.4 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) GIT1_C PF12205.8 GBG68729.1 - 6.4 6.9 7.4 64 3.7 0.1 3.6 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term RT_RNaseH_2 PF17919.1 GBG68732.1 - 5.6e-25 87.3 0.0 1.2e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68732.1 - 9.3e-24 83.7 0.0 1.7e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68732.1 - 1.8e-18 66.4 0.1 3.4e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG68732.1 - 2.1e-05 24.3 0.0 4.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68732.1 - 0.00059 20.4 0.0 0.0013 19.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68732.1 - 0.015 15.8 0.0 0.032 14.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF5471 PF17565.2 GBG68732.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5471) zf-H2C2 PF09337.10 GBG68732.1 - 0.11 12.7 0.0 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger TauE PF01925.19 GBG68733.1 - 4.9e-19 68.9 34.1 2.1e-12 47.2 3.7 3.4 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE UL42 PF17638.2 GBG68733.1 - 0.021 14.8 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 HCMV UL42 Mito_fiss_reg PF05308.11 GBG68733.1 - 0.63 10.1 5.5 0.12 12.5 1.3 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator RT_RNaseH_2 PF17919.1 GBG68734.1 - 7.2e-27 93.4 0.0 1.2e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68734.1 - 6.2e-24 84.3 0.0 1.1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68734.1 - 2.9e-11 43.3 0.1 4.1e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) B_lectin PF01453.24 GBG68736.1 - 5.3e-08 33.4 6.2 6.2e-06 26.7 0.0 5.0 5 1 1 6 6 6 1 D-mannose binding lectin MLANA PF14991.6 GBG68736.1 - 0.086 13.1 0.0 0.34 11.2 0.0 2.0 1 0 0 1 1 1 0 Protein melan-A TMEM154 PF15102.6 GBG68736.1 - 0.25 11.3 4.6 0.92 9.4 0.0 3.3 3 0 0 3 3 3 0 TMEM154 protein family DUF4366 PF14283.6 GBG68736.1 - 0.36 10.9 1.2 1.4 9.0 1.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) IFT57 PF10498.9 GBG68737.1 - 0.022 13.7 10.9 0.048 12.6 10.9 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4140 PF13600.6 GBG68737.1 - 0.059 13.8 0.5 0.42 11.1 0.5 2.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4239 PF14023.6 GBG68737.1 - 0.97 9.1 3.8 0.21 11.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) PEARLI-4 PF05278.12 GBG68737.1 - 1.1 8.8 11.2 2.8 7.5 11.2 1.7 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) PikAIV_N PF18605.1 GBG68737.1 - 6.8 6.4 8.0 0.23 11.1 0.4 2.6 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DDE_Tnp_4 PF13359.6 GBG68738.1 - 2.9e-25 88.8 0.0 1e-24 87.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68738.1 - 3.1e-12 46.5 0.0 5.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68738.1 - 0.044 13.4 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain HTH_48 PF17906.1 GBG68738.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Myb_DNA-bind_4 PF13837.6 GBG68739.1 - 1.3e-08 35.1 0.3 2.4e-08 34.2 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG68739.1 - 0.0096 16.0 1.7 0.019 15.0 1.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain NifU PF01106.17 GBG68740.1 - 3.3e-37 126.4 7.2 3.2e-26 91.2 0.1 2.6 3 0 0 3 3 3 2 NifU-like domain PPR PF01535.20 GBG68741.1 - 1.6e-40 134.5 4.0 6.9e-05 22.8 0.0 9.4 9 0 0 9 9 9 8 PPR repeat PPR_2 PF13041.6 GBG68741.1 - 2.1e-32 111.0 0.3 0.00012 22.2 0.0 7.9 4 3 4 8 8 8 7 PPR repeat family PPR_1 PF12854.7 GBG68741.1 - 2.8e-24 84.5 0.0 0.00015 21.3 0.0 8.3 8 0 0 8 8 8 5 PPR repeat PPR_3 PF13812.6 GBG68741.1 - 3e-19 68.8 0.0 0.0019 18.2 0.0 5.7 4 1 2 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG68741.1 - 9.3e-13 48.0 0.0 1.2e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG68741.1 - 0.00015 22.2 0.5 5.4 7.6 0.0 4.0 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG68741.1 - 0.029 15.2 15.3 6.2 7.9 0.4 6.0 5 1 1 6 6 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GBG68741.1 - 0.049 13.5 1.8 8.7 6.2 0.0 2.9 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_7 PF13176.6 GBG68741.1 - 0.1 12.7 4.3 6.2 7.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 GBG68741.1 - 0.27 12.0 15.4 2.1 9.2 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG68741.1 - 1.8 8.9 5.4 8.5 6.7 0.2 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat NOA36 PF06524.12 GBG68741.1 - 4.5 6.5 7.7 8.6 5.6 7.7 1.4 1 0 0 1 1 1 0 NOA36 protein DUF1664 PF07889.12 GBG68742.1 - 0.0037 17.3 1.7 0.0099 15.9 1.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF908 PF06012.12 GBG68742.1 - 0.071 12.5 0.6 0.17 11.2 0.6 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Rota_NS53 PF00981.17 GBG68742.1 - 0.11 11.4 0.4 0.16 10.8 0.4 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Bap31_Bap29_C PF18035.1 GBG68742.1 - 0.23 11.5 4.9 0.66 10.0 4.9 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain zf-CCHC_5 PF14787.6 GBG68742.1 - 0.51 10.1 2.5 1.2 8.9 2.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DDE_Tnp_4 PF13359.6 GBG68744.1 - 0.0014 18.3 0.7 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease Peptidase_C48 PF02902.19 GBG68746.1 - 1.2e-15 58.0 0.0 1.9e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3824 PF12868.7 GBG68747.1 - 0.09 13.4 3.5 0.22 12.2 3.5 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) WD40 PF00400.32 GBG68748.1 - 2.3e-12 47.2 9.3 0.00013 22.6 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG68748.1 - 0.00019 21.7 1.3 8 6.8 0.0 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain AdoHcyase PF05221.17 GBG68749.1 - 0.068 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase DUF1664 PF07889.12 GBG68750.1 - 8.6 6.4 12.5 17 5.5 0.3 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) MMS19_N PF14500.6 GBG68752.1 - 0.0075 15.9 0.4 0.044 13.4 0.1 2.2 1 1 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II Xpo1 PF08389.12 GBG68752.1 - 0.014 15.4 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 0 Exportin 1-like protein RexA PF15969.5 GBG68752.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component HEAT_EZ PF13513.6 GBG68752.1 - 3.5 8.2 9.3 1.4 9.5 0.4 4.5 4 2 2 6 6 6 0 HEAT-like repeat HEAT PF02985.22 GBG68752.1 - 7.7 7.1 8.7 9.3 6.8 0.0 4.8 6 0 0 6 6 6 0 HEAT repeat IFRD PF05004.13 GBG68753.1 - 5.1e-05 22.5 0.9 0.00013 21.2 0.7 1.7 1 1 1 2 2 2 1 Interferon-related developmental regulator (IFRD) MMS19_N PF14500.6 GBG68753.1 - 0.0099 15.5 0.2 0.035 13.7 0.2 2.0 1 1 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II Xpo1 PF08389.12 GBG68753.1 - 0.012 15.7 0.0 0.097 12.7 0.0 2.5 2 0 0 2 2 2 0 Exportin 1-like protein RexA PF15969.5 GBG68753.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component UNC45-central PF11701.8 GBG68753.1 - 0.12 12.3 0.1 5.3 7.0 0.2 2.5 1 1 1 2 2 2 0 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 GBG68753.1 - 6.1 7.5 9.3 1.4 9.5 0.5 4.1 3 2 2 5 5 5 0 HEAT-like repeat MMS19_N PF14500.6 GBG68754.1 - 0.01 15.4 0.2 0.042 13.4 0.1 2.0 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Xpo1 PF08389.12 GBG68754.1 - 0.013 15.5 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 0 Exportin 1-like protein HEAT_2 PF13646.6 GBG68754.1 - 0.05 14.0 0.0 0.58 10.6 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats RexA PF15969.5 GBG68754.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component HEAT_EZ PF13513.6 GBG68754.1 - 5.7 7.6 6.9 17 6.0 0.1 4.6 3 2 3 6 6 6 0 HEAT-like repeat HEAT PF02985.22 GBG68754.1 - 8 7.0 8.9 9.4 6.8 0.0 4.8 6 0 0 6 6 6 0 HEAT repeat UPF0014 PF03649.13 GBG68755.1 - 9.8e-60 201.9 13.6 1.4e-59 201.3 13.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) CPP1-like PF11833.8 GBG68755.1 - 2.2 7.9 5.9 4.4 6.9 5.2 1.8 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like RVT_1 PF00078.27 GBG68757.1 - 8.2e-31 107.2 0.1 1.3e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68757.1 - 1e-25 89.7 0.0 3e-25 88.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68757.1 - 4.2e-23 81.6 0.0 1.2e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68757.1 - 1.1e-17 63.9 0.7 3.2e-17 62.4 0.5 2.1 2 0 0 2 2 1 1 Integrase zinc binding domain rve PF00665.26 GBG68757.1 - 6.2e-08 32.9 0.0 2.3e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG68757.1 - 6.3e-07 30.0 0.0 1.8e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68757.1 - 1.5e-06 28.7 0.0 5.4e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG68757.1 - 0.00023 20.9 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG68757.1 - 0.0029 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG68757.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF3006 PF11213.8 GBG68757.1 - 0.034 14.4 2.7 0.37 11.1 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) CCDC84 PF14968.6 GBG68757.1 - 0.25 10.9 6.1 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Coiled coil protein 84 Glyoxalase PF00903.25 GBG68758.1 - 1.4e-11 44.7 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GBG68758.1 - 4.4e-06 26.9 0.0 6.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 GBG68758.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain CBM_48 PF02922.18 GBG68759.1 - 5.1e-19 68.4 0.1 1.4e-18 67.0 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 GBG68759.1 - 8.2e-16 58.3 0.0 3.6e-15 56.2 0.0 2.1 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 GBG68759.1 - 8.3e-12 45.3 0.8 8.3e-12 45.3 0.8 3.2 2 1 1 3 3 3 2 Alpha amylase, catalytic domain Spt20 PF12090.8 GBG68759.1 - 7.7 6.1 13.6 13 5.3 13.6 1.2 1 0 0 1 1 1 0 Spt20 family MIF4G_like_2 PF09090.11 GBG68760.1 - 1.2 8.5 12.2 8 5.9 0.0 2.1 1 1 1 2 2 2 0 MIF4G like AAA_13 PF13166.6 GBG68760.1 - 1.4 7.5 11.3 1.6 7.3 11.3 1.1 1 0 0 1 1 1 0 AAA domain FemAB PF02388.16 GBG68760.1 - 2.2 7.0 5.4 4.6 6.0 5.4 1.5 1 0 0 1 1 1 0 FemAB family DUF4192 PF13830.6 GBG68760.1 - 8.6 6.3 9.5 11 6.0 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) RT_RNaseH_2 PF17919.1 GBG68761.1 - 8.7e-23 80.2 0.0 1.9e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Aminotran_4 PF01063.19 GBG68761.1 - 4.2e-19 69.3 0.0 5.8e-18 65.6 0.0 2.5 1 1 0 1 1 1 1 Amino-transferase class IV RT_RNaseH PF17917.1 GBG68761.1 - 4.8e-10 39.7 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68761.1 - 8.5e-08 32.0 0.1 1.3e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pollen_allerg_1 PF01357.21 GBG68762.1 - 3.8e-11 42.8 0.0 5.8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.18 GBG68762.1 - 2.2e-08 34.2 2.1 2.3e-08 34.2 0.1 2.0 2 0 0 2 2 2 1 Lytic transglycolase DUF3755 PF12579.8 GBG68763.1 - 2.4e-13 49.5 0.0 4.8e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3755) Antimicrobial_6 PF08036.11 GBG68764.1 - 0.016 15.3 1.5 3 8.0 0.5 2.8 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide RT_RNaseH_2 PF17919.1 GBG68765.1 - 1.7e-59 198.1 0.1 9.5e-30 102.6 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68765.1 - 2.5e-52 175.6 0.2 7.5e-25 87.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68765.1 - 8e-24 84.4 0.2 9.7e-19 67.8 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG68765.1 - 3.6e-14 53.0 0.0 1.1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Mcp5_PH PF12814.7 GBG68765.1 - 0.0057 16.8 5.9 0.45 10.6 1.0 2.5 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology zf-CCHC_3 PF13917.6 GBG68765.1 - 0.02 14.9 2.1 0.051 13.5 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF5095 PF17016.5 GBG68765.1 - 0.13 11.9 0.2 0.32 10.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) DUF454 PF04304.13 GBG68765.1 - 0.38 10.8 1.5 17 5.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF454) Malic_M PF03949.15 GBG68766.1 - 1.1e-86 290.3 0.5 1.4e-86 290.0 0.5 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GBG68766.1 - 8.3e-75 250.6 0.1 7.1e-74 247.5 0.0 2.1 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain SLH PF00395.20 GBG68767.1 - 9.5e-06 25.5 0.0 0.0052 16.8 0.0 3.4 2 1 0 2 2 2 2 S-layer homology domain Big_3_2 PF12245.8 GBG68767.1 - 0.02 15.2 0.2 0.058 13.7 0.2 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain SLBP_RNA_bind PF15247.6 GBG68768.1 - 6e-31 106.4 3.4 6e-31 106.4 3.4 1.9 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain HAD_2 PF13419.6 GBG68769.1 - 6.1e-20 72.1 0.0 1.5e-19 70.7 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GBG68769.1 - 1.6e-13 51.5 0.0 2.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG68769.1 - 2.8e-06 27.3 0.0 6.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Glu_cyclase_2 PF05096.12 GBG68771.1 - 8.1e-87 290.8 0.0 9.7e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase SGL PF08450.12 GBG68771.1 - 0.0023 17.6 0.2 0.062 12.9 0.2 3.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Pyridox_oxase_2 PF12766.7 GBG68772.1 - 9.9e-28 96.7 0.0 1.6e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 GBG68772.1 - 3.3e-07 30.4 0.0 5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glu_cyclase_2 PF05096.12 GBG68773.1 - 8.1e-87 290.8 0.0 9.7e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase SGL PF08450.12 GBG68773.1 - 0.0023 17.6 0.2 0.062 12.9 0.2 3.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region GDC-P PF02347.16 GBG68774.1 - 5.2e-188 625.2 3.7 3.1e-179 596.3 0.0 4.1 3 1 1 4 4 4 4 Glycine cleavage system P-protein ALS2CR11 PF15729.5 GBG68775.1 - 7.3e-06 25.4 0.1 1.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 candidate 11 C2 PF00168.30 GBG68775.1 - 0.014 15.7 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 C2 domain NT-C2 PF10358.9 GBG68775.1 - 0.047 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Phage_Gp23 PF10669.9 GBG68775.1 - 0.14 12.5 2.3 0.33 11.3 2.3 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RVT_1 PF00078.27 GBG68776.1 - 1.2e-32 113.3 0.1 2.2e-32 112.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68776.1 - 1.7e-21 76.5 0.1 8.6e-21 74.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68776.1 - 6.2e-17 61.5 0.0 1.7e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG68776.1 - 0.035 14.4 0.3 0.035 14.4 0.3 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein Integrin_b_cyt PF08725.11 GBG68776.1 - 0.097 12.4 0.1 0.28 10.9 0.1 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain CENP-K PF11802.8 GBG68776.1 - 0.43 10.1 3.8 0.99 8.9 3.8 1.5 1 0 0 1 1 1 0 Centromere-associated protein K MscS_TM PF12794.7 GBG68776.1 - 0.71 8.7 3.5 0.4 9.5 0.0 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Mt_ATP-synt_B PF05405.14 GBG68776.1 - 4.8 6.8 8.6 3.8 7.1 6.8 1.7 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Kazal_2 PF07648.15 GBG68778.1 - 1.8e-16 60.0 36.9 1.1e-05 25.5 7.6 4.8 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 GBG68778.1 - 0.0051 16.8 34.7 0.29 11.2 3.1 5.3 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain DUF4551 PF15087.6 GBG68778.1 - 0.28 10.0 2.0 0.41 9.4 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RVT_1 PF00078.27 GBG68779.1 - 9.1e-32 110.4 0.3 3.6e-31 108.4 0.0 2.1 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68779.1 - 4.1e-23 81.3 0.0 2.2e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68779.1 - 3.1e-22 78.9 0.0 7.2e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG68779.1 - 4.5e-11 42.7 0.0 1.5e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68779.1 - 1.5e-08 35.1 0.0 3.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68779.1 - 3.2e-06 27.6 0.0 1.2e-05 25.8 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG68779.1 - 0.00035 20.8 0.0 0.0019 18.4 0.0 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG68779.1 - 0.011 15.5 0.0 0.057 13.2 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease TolA_bind_tri PF16331.5 GBG68779.1 - 0.016 15.3 3.8 0.038 14.1 3.8 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF1664 PF07889.12 GBG68779.1 - 0.084 12.9 0.6 0.36 10.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 GBG68779.1 - 0.23 10.3 1.3 0.44 9.4 1.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ubiquitin PF00240.23 GBG68780.1 - 0.052 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family TPT PF03151.16 GBG68781.1 - 2e-108 362.2 22.1 2.6e-108 361.8 22.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG68781.1 - 4.1e-10 40.0 28.6 5.8e-05 23.3 11.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family TRAP_alpha PF03896.16 GBG68782.1 - 0.16 11.2 6.6 0.18 11.0 6.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 GBG68782.1 - 0.97 7.4 28.2 1.1 7.3 28.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GBG68782.1 - 2.3 6.7 19.3 2.6 6.5 19.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 GBG68782.1 - 4.4 6.6 14.9 4.9 6.5 14.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RVT_1 PF00078.27 GBG68783.1 - 6.6e-30 104.3 0.1 9.8e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG68783.1 - 0.075 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Presenilin PF01080.17 GBG68784.1 - 10 4.8 6.8 12 4.6 6.8 1.2 1 0 0 1 1 1 0 Presenilin Asp_protease_2 PF13650.6 GBG68785.1 - 2.8e-06 27.9 0.0 8.6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG68785.1 - 3.4e-05 23.6 0.0 9.8e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG68785.1 - 0.00016 22.2 0.0 0.00069 20.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG68785.1 - 0.0029 17.8 0.3 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG68785.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease TolA_bind_tri PF16331.5 GBG68785.1 - 0.073 13.2 3.5 0.15 12.2 3.5 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation TRPM_tetra PF16519.5 GBG68785.1 - 0.13 12.4 3.1 8.3 6.6 0.2 3.2 3 0 0 3 3 3 0 Tetramerisation domain of TRPM MIF4G_like_2 PF09090.11 GBG68785.1 - 0.16 11.4 1.2 0.17 11.4 0.2 1.4 2 0 0 2 2 2 0 MIF4G like DUF3763 PF12592.8 GBG68785.1 - 0.3 11.2 1.9 3.9 7.6 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3763) CDC45 PF02724.14 GBG68786.1 - 0.099 10.9 9.9 0.14 10.4 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 GBG68786.1 - 0.53 10.0 3.2 0.97 9.1 3.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Nop14 PF04147.12 GBG68786.1 - 2.7 6.1 13.6 3.3 5.8 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG68786.1 - 7.2 5.8 19.1 10 5.4 19.1 1.1 1 0 0 1 1 1 0 BUD22 MatE PF01554.18 GBG68787.1 - 8.7e-09 35.2 17.0 0.00023 20.9 7.5 2.6 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GBG68787.1 - 1.3e-06 28.6 4.7 1.3e-06 28.6 4.7 3.0 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain UCH PF00443.29 GBG68788.1 - 2.9e-51 174.4 0.0 3.5e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG68788.1 - 3.9e-15 56.3 1.1 1.1e-14 54.8 1.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 GBG68788.1 - 1e-06 28.4 0.1 3.7e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Peptidase_C98 PF15499.6 GBG68788.1 - 9.3e-05 22.0 1.6 0.0047 16.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase FYRC PF05965.14 GBG68788.1 - 0.12 12.6 0.1 0.31 11.2 0.1 1.7 1 0 0 1 1 1 0 F/Y rich C-terminus Glycos_transf_1 PF00534.20 GBG68789.1 - 4.5e-27 94.7 0.0 1.3e-26 93.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG68789.1 - 4.5e-26 91.9 0.0 4.5e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG68789.1 - 2.9e-25 89.2 0.0 7.4e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GBG68789.1 - 4.2e-16 59.8 0.0 4.2e-16 59.8 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GBG68789.1 - 3.3e-09 37.0 1.7 3.5e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 GBG68789.1 - 1.1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Zip PF02535.22 GBG68790.1 - 2 7.6 5.5 5 6.3 5.5 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter RVT_1 PF00078.27 GBG68791.1 - 7.1e-29 100.9 0.1 1.1e-28 100.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG68791.1 - 0.01 16.5 0.0 0.072 13.7 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG68792.1 - 4e-23 81.8 0.3 5.8e-12 45.6 0.0 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68792.1 - 3.2e-11 43.2 0.0 2.2e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68792.1 - 0.0024 17.6 0.7 1.7 8.2 0.2 2.4 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG68792.1 - 0.0048 17.2 0.7 0.013 15.8 0.1 2.0 2 0 0 2 2 2 1 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG68793.1 - 4.7e-32 110.0 0.1 1e-31 108.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68793.1 - 2.4e-28 98.5 0.1 5.6e-28 97.3 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68793.1 - 8.4e-26 90.9 0.1 1.4e-25 90.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG68793.1 - 9.8e-20 70.4 0.1 2.3e-19 69.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68793.1 - 3.4e-15 56.3 0.0 1.6e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG68793.1 - 0.044 14.0 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG68794.1 - 0.00069 20.0 0.3 0.0012 19.2 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PSK_trans_fac PF07704.11 GBG68794.1 - 0.082 13.7 3.0 0.32 11.8 3.0 2.0 1 0 0 1 1 1 0 Rv0623-like transcription factor DUF659 PF04937.15 GBG68795.1 - 9.7e-19 67.7 0.0 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CDC45 PF02724.14 GBG68795.1 - 8.1 4.6 11.2 21 3.3 11.2 1.6 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG68796.1 - 0.15 10.3 10.6 0.15 10.2 10.6 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG68796.1 - 3.7 5.7 11.2 4.4 5.5 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein PAT1 PF09770.9 GBG68797.1 - 0.13 10.6 15.2 0.16 10.2 15.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Y2_Tnp PF04986.13 GBG68797.1 - 2.5 8.1 8.1 0.049 13.7 1.2 1.6 2 0 0 2 2 2 0 Putative transposase LBP_C PF17386.2 GBG68798.1 - 0.029 14.2 0.1 0.06 13.3 0.1 1.5 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase C-terminal domain Tmemb_9 PF05434.11 GBG68798.1 - 2.9 7.8 0.0 2.9 7.8 0.0 2.6 2 1 0 2 2 2 0 TMEM9 gag-asp_proteas PF13975.6 GBG68799.1 - 9.6e-06 26.1 0.0 3e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68799.1 - 0.00088 19.9 0.0 0.0023 18.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG68799.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG68799.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG68800.1 - 1.1e-31 110.1 0.1 2e-31 109.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68800.1 - 8.2e-31 106.0 0.1 2.5e-30 104.5 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68800.1 - 6.9e-27 93.8 0.2 1.7e-26 92.5 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68800.1 - 6.6e-17 61.4 0.0 1.7e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68800.1 - 7.3e-17 61.7 0.1 1.9e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG68800.1 - 7.2e-06 26.5 0.0 2.1e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68800.1 - 0.00029 21.4 0.0 0.00082 20.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF1564 PF07600.11 GBG68800.1 - 0.013 15.2 0.5 0.039 13.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DUF1758 PF05585.12 GBG68800.1 - 0.02 14.7 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG68800.1 - 0.1 12.9 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG68800.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DAPDH_C PF16654.5 GBG68800.1 - 0.14 12.0 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain RVT_1 PF00078.27 GBG68801.1 - 3.7e-26 92.0 0.0 5.6e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68801.1 - 1.3e-25 89.4 0.0 2.2e-16 59.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68801.1 - 1.8e-13 50.6 0.0 4.5e-13 49.4 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SR-25 PF10500.9 GBG68803.1 - 4.2 6.9 7.5 6 6.4 7.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Myb_DNA-bind_4 PF13837.6 GBG68804.1 - 8.3e-05 22.9 0.5 0.00018 21.8 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG68804.1 - 0.18 11.9 2.0 0.27 11.3 0.4 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 GBG68805.1 - 0.00076 19.7 0.4 0.027 14.7 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein DUF2781 PF10914.8 GBG68805.1 - 0.023 15.1 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Rotamase_2 PF13145.6 GBG68805.1 - 1.4 9.8 11.3 2 9.2 6.9 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain RVT_1 PF00078.27 GBG68806.1 - 3.1e-27 95.5 0.1 5.1e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68806.1 - 8.3e-26 89.9 0.0 1.8e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68806.1 - 4.4e-24 84.8 0.0 8.3e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68806.1 - 2.1e-18 66.2 0.5 7.7e-18 64.4 0.3 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG68806.1 - 3.1e-09 37.0 0.0 7.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG68806.1 - 0.03 14.2 0.1 0.055 13.4 0.1 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG68806.1 - 0.14 12.4 0.2 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 H2C2 zinc finger DUF4774 PF15999.5 GBG68806.1 - 0.22 11.4 0.4 0.44 10.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) HIP1_clath_bdg PF16515.5 GBG68807.1 - 0.011 16.3 7.1 0.011 16.3 7.1 3.6 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Snapin_Pallidin PF14712.6 GBG68807.1 - 0.035 14.5 4.3 0.035 14.5 4.3 2.9 3 0 0 3 3 3 0 Snapin/Pallidin Retrotrans_gag PF03732.17 GBG68807.1 - 0.16 12.3 12.8 5.2 7.4 0.1 3.7 3 1 0 3 3 3 0 Retrotransposon gag protein NPV_P10 PF05531.12 GBG68807.1 - 0.45 11.0 8.5 1.7 9.2 1.5 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SPACA9 PF15120.6 GBG68807.1 - 0.65 9.8 7.6 0.028 14.2 1.8 1.7 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 FlaC_arch PF05377.11 GBG68807.1 - 1.3 9.5 4.4 31 5.1 1.2 3.4 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ERM PF00769.19 GBG68807.1 - 3 7.6 30.6 1.1 9.1 24.6 2.2 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Spc24 PF08286.11 GBG68807.1 - 7.2 6.9 16.8 1.7 8.9 3.1 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 GBG68807.1 - 8.2 6.5 8.4 8.1 6.5 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 GBG68807.1 - 9.3 6.6 13.8 0.28 11.5 3.2 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RT_RNaseH_2 PF17919.1 GBG68808.1 - 2.6e-24 85.1 0.0 5.2e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68808.1 - 1.4e-22 79.9 0.0 6.5e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68808.1 - 7.6e-15 55.2 0.0 2.6e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG68808.1 - 6.6e-14 51.8 0.0 1.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG68808.1 - 0.0091 15.8 0.0 0.032 14.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG68808.1 - 0.076 13.3 0.5 0.41 10.9 0.1 2.3 2 1 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG68809.1 - 3.5e-21 75.4 0.0 9.3e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68809.1 - 1.4e-20 73.2 0.0 3.3e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LRRNT_2 PF08263.12 GBG68809.1 - 2.2e-10 40.7 1.1 5e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain RVT_1 PF00078.27 GBG68809.1 - 0.00062 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5572 PF17733.1 GBG68811.1 - 4.3e-13 48.9 3.3 1.5e-12 47.1 3.3 2.1 1 0 0 1 1 1 1 Family of unknown function (DUF5572) RT_RNaseH_2 PF17919.1 GBG68812.1 - 1.1e-26 92.8 0.0 2.4e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68812.1 - 1.9e-26 93.0 0.1 4.7e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68812.1 - 4.1e-24 84.9 0.0 7.7e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase tRNA_lig_CPD PF08302.11 GBG68812.1 - 0.028 13.8 0.1 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain Pex14_N PF04695.13 GBG68813.1 - 5.5e-27 95.4 4.2 5.8e-27 95.3 0.2 2.5 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TerB PF05099.13 GBG68813.1 - 0.12 12.3 6.0 0.15 12.0 4.6 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TerB Pex14_N PF04695.13 GBG68814.1 - 5.5e-27 95.4 4.2 5.8e-27 95.3 0.2 2.5 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TerB PF05099.13 GBG68814.1 - 0.12 12.3 6.0 0.15 12.0 4.6 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TerB RT_RNaseH_2 PF17919.1 GBG68815.1 - 1.4e-28 98.8 0.0 3.4e-28 97.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68815.1 - 1e-27 96.5 0.0 2.8e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68815.1 - 2e-19 70.0 0.1 7.8e-09 35.4 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG68815.1 - 4.9e-08 32.8 0.0 8.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG68815.1 - 7e-05 22.9 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG68815.1 - 0.042 14.1 0.3 0.42 10.9 0.0 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein CAP_N PF01213.19 GBG68815.1 - 9.8 5.6 6.1 23 4.3 6.1 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CDP-OH_P_transf PF01066.21 GBG68816.1 - 2.9e-09 37.6 0.2 6.9e-09 36.3 0.2 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Histone PF00125.24 GBG68817.1 - 8.2e-15 55.3 0.2 8.2e-15 55.3 0.2 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG68817.1 - 0.055 13.8 0.1 0.17 12.3 0.1 1.7 2 0 0 2 2 2 0 CENP-S protein CENP-T_C PF15511.6 GBG68818.1 - 9.7e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GBG68818.1 - 2e-05 24.9 0.1 2.6e-05 24.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 GBG68818.1 - 0.0012 18.9 0.1 0.0017 18.5 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 GBG68818.1 - 0.0024 18.1 0.1 0.0037 17.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GBG68818.1 - 0.0024 18.2 0.2 0.0026 18.1 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 GBG68818.1 - 0.0037 17.2 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 GBG68818.1 - 0.014 15.4 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit UPF0137 PF03677.13 GBG68818.1 - 0.22 11.3 0.1 0.27 11.0 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) DUF1206 PF06724.11 GBG68819.1 - 0.11 12.6 3.2 0.89 9.7 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) PSI_PsaF PF02507.15 GBG68819.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III DUF3246 PF11596.8 GBG68820.1 - 0.039 13.4 9.0 0.062 12.7 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 GBG68820.1 - 0.088 13.2 20.6 0.052 13.9 11.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RT_RNaseH_2 PF17919.1 GBG68822.1 - 3.3e-23 81.6 0.3 8.6e-23 80.3 0.2 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68822.1 - 2.7e-15 56.5 0.1 3.8e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68822.1 - 3.7e-10 40.0 0.1 8.4e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Tudor_2 PF18104.1 GBG68823.1 - 0.00091 18.9 8.0 1.2 8.8 0.3 4.9 5 0 0 5 5 5 2 Jumonji domain-containing protein 2A Tudor domain DUF2862 PF11061.8 GBG68823.1 - 0.36 10.7 6.9 24 4.9 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2862) bZIP_2 PF07716.15 GBG68825.1 - 0.012 15.6 23.9 2.6 8.2 0.2 6.4 6 0 0 6 6 6 0 Basic region leucine zipper Tup_N PF08581.10 GBG68825.1 - 0.017 15.4 0.7 0.017 15.4 0.7 3.9 4 1 0 4 4 4 0 Tup N-terminal NRBF2 PF08961.10 GBG68825.1 - 0.054 13.1 15.4 0.11 12.1 0.5 3.8 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Sec2p PF06428.11 GBG68825.1 - 0.1 12.6 14.7 1.7 8.7 0.1 4.0 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Mto2_bdg PF12808.7 GBG68825.1 - 0.1 12.9 9.5 1.3 9.4 0.6 4.0 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Herpes_BLRF2 PF05812.12 GBG68825.1 - 0.15 12.2 0.3 0.15 12.2 0.3 3.8 2 1 3 5 5 5 0 Herpesvirus BLRF2 protein DivIC PF04977.15 GBG68825.1 - 0.16 11.8 19.8 0.12 12.2 0.6 5.4 4 2 2 6 6 6 0 Septum formation initiator SHE3 PF17078.5 GBG68825.1 - 0.2 11.3 14.3 1.1 8.9 7.1 3.0 2 1 2 4 4 4 0 SWI5-dependent HO expression protein 3 YabA PF06156.13 GBG68825.1 - 0.24 12.0 13.9 0.32 11.7 0.5 3.8 1 1 1 2 2 2 0 Initiation control protein YabA JIP_LZII PF16471.5 GBG68825.1 - 0.65 10.2 10.6 6.6 7.0 0.1 4.8 3 1 2 5 5 5 0 JNK-interacting protein leucine zipper II FlaC_arch PF05377.11 GBG68825.1 - 0.96 9.9 14.4 24 5.4 0.1 5.5 4 1 3 7 7 7 0 Flagella accessory protein C (FlaC) DUF4515 PF14988.6 GBG68825.1 - 1.3 8.8 20.8 0.03 14.2 3.8 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4515) Hemerythrin PF01814.23 GBG68825.1 - 2.4 8.8 6.7 23 5.6 0.3 3.3 1 1 3 4 4 4 0 Hemerythrin HHE cation binding domain CCDC92 PF14916.6 GBG68825.1 - 2.6 7.9 15.2 17 5.3 0.5 5.2 2 1 3 5 5 5 0 Coiled-coil domain of unknown function BLOC1_2 PF10046.9 GBG68825.1 - 3 8.2 13.2 2.4 8.5 0.4 4.5 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KASH_CCD PF14662.6 GBG68825.1 - 4 7.2 23.2 1.3e+02 2.3 18.2 4.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH betaPIX_CC PF16523.5 GBG68825.1 - 4.4 7.2 19.7 2.1 8.2 3.6 4.4 3 1 0 5 5 5 0 betaPIX coiled coil ABC_tran_CTD PF16326.5 GBG68825.1 - 5.2 7.4 12.6 0.2 11.9 0.4 3.7 3 1 1 4 4 4 0 ABC transporter C-terminal domain MatE PF01554.18 GBG68826.1 - 4.4e-23 81.7 33.0 1.9e-15 56.9 3.8 3.7 3 1 0 3 3 3 2 MatE Yip1 PF04893.17 GBG68828.1 - 6e-14 52.1 10.2 1.9e-13 50.5 10.2 1.8 1 1 0 1 1 1 1 Yip1 domain Cation_ATPase_C PF00689.21 GBG68828.1 - 0.0011 18.7 0.2 0.0011 18.7 0.2 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus YIF1 PF03878.15 GBG68828.1 - 0.002 17.7 3.9 0.074 12.6 3.9 2.1 1 1 0 1 1 1 1 YIF1 DUF3752 PF12572.8 GBG68829.1 - 0.22 12.0 4.8 0.34 11.4 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) PMI_typeI PF01238.21 GBG68830.1 - 8.5e-100 334.5 0.0 1.2e-52 179.3 0.0 2.1 2 0 0 2 2 2 2 Phosphomannose isomerase type I Cupin_2 PF07883.11 GBG68830.1 - 0.093 12.5 0.1 9.2 6.1 0.0 3.0 3 0 0 3 3 3 0 Cupin domain DUF3362 PF11842.8 GBG68831.1 - 0.11 12.9 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) V-ATPase_H_N PF03224.14 GBG68832.1 - 6.4e-55 186.6 4.3 3.4e-51 174.4 2.5 2.9 1 1 1 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 GBG68832.1 - 5.3e-14 52.3 3.9 2.7e-12 46.9 0.5 2.8 2 1 1 3 3 3 2 V-ATPase subunit H DUF2428 PF10350.9 GBG68832.1 - 0.0045 16.3 0.1 0.012 14.9 0.1 1.7 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 GBG68832.1 - 0.016 15.6 0.1 0.27 11.6 0.0 3.0 4 0 0 4 4 4 0 HEAT repeats Peptidase_C6 PF00851.18 GBG68832.1 - 0.096 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Helper component proteinase Plavaka PF18759.1 GBG68833.1 - 1.5e-07 31.0 0.1 3.1e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Plavaka transposase DUF5476 PF17570.2 GBG68835.1 - 0.92 9.9 3.8 0.96 9.9 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5476) Branch PF02485.21 GBG68837.1 - 3.2e-52 177.5 0.0 5.2e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Dscam_C PF12355.8 GBG68837.1 - 0.0037 18.2 6.7 0.05 14.5 2.6 3.1 2 0 0 2 2 2 1 Down syndrome cell adhesion molecule C terminal TFIIE-A_C PF11521.8 GBG68837.1 - 0.03 14.6 0.2 0.03 14.6 0.2 4.6 5 0 0 5 5 5 0 C-terminal general transcription factor TFIIE alpha Jak1_Phl PF17887.1 GBG68837.1 - 1.9 8.5 4.8 6 6.8 4.8 1.8 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain TMEM171 PF15471.6 GBG68837.1 - 3 6.8 5.0 9.4 5.1 5.0 1.8 1 0 0 1 1 1 0 Transmembrane protein family 171 RT_RNaseH_2 PF17919.1 GBG68838.1 - 1.1e-28 99.1 0.0 2.1e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68838.1 - 5.7e-25 87.6 0.0 1.2e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68838.1 - 5e-08 32.7 0.0 7.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFB6 PF17110.5 GBG68838.1 - 6.2 6.5 7.0 18 5.0 0.0 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH RT_RNaseH_2 PF17919.1 GBG68839.1 - 2.7e-32 110.8 0.0 6e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68839.1 - 4.9e-31 107.1 0.1 1.3e-30 105.8 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68839.1 - 1.7e-27 96.4 0.2 3.5e-27 95.4 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG68839.1 - 1.4e-14 54.3 0.0 5.1e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG68839.1 - 0.031 14.0 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG68839.1 - 0.036 14.3 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein CLZ PF16526.5 GBG68839.1 - 6.1 7.3 6.6 2 8.8 0.0 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Rieske PF00355.26 GBG68840.1 - 1.1e-22 79.7 0.7 4.7e-22 77.7 0.1 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG68840.1 - 4.2e-14 52.5 0.0 1.2e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Pheophorbide a oxygenase Rieske_2 PF13806.6 GBG68840.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain RVT_1 PF00078.27 GBG68841.1 - 2.1e-34 119.0 0.1 3.9e-34 118.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68841.1 - 3.3e-29 100.8 0.1 4.7e-28 97.2 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68841.1 - 2.9e-27 95.0 0.3 4.3e-26 91.2 0.1 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68841.1 - 1.1e-18 67.0 1.2 2.8e-18 65.8 1.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68841.1 - 1.6e-17 63.8 0.0 4.9e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG68841.1 - 3e-08 33.5 0.0 5.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG68841.1 - 0.00022 21.8 0.0 0.00056 20.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG68841.1 - 0.0011 19.2 0.1 0.0035 17.5 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG68841.1 - 0.0029 18.1 0.0 0.0085 16.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG68841.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Beta_helix PF13229.6 GBG68842.1 - 0.0012 18.7 7.5 0.0072 16.2 7.6 1.9 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG68842.1 - 0.0022 18.4 10.5 2.8 8.6 0.3 5.9 6 0 0 6 6 6 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RVT_1 PF00078.27 GBG68843.1 - 3.2e-16 59.5 0.0 5.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG68843.1 - 6.8e-06 25.9 3.2 1.3e-05 25.0 3.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG68843.1 - 0.012 15.4 4.1 0.026 14.4 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle SapB_1 PF05184.15 GBG68846.1 - 2e-19 69.3 3.3 1.5e-07 31.3 0.1 3.7 3 0 0 3 3 3 3 Saposin-like type B, region 1 SapB_2 PF03489.17 GBG68846.1 - 3.6e-13 49.4 4.2 0.0023 18.0 0.0 4.0 3 0 0 3 3 3 3 Saposin-like type B, region 2 Med5 PF08689.10 GBG68846.1 - 0.073 10.9 0.0 0.1 10.4 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 WD40 PF00400.32 GBG68846.1 - 5.8 8.0 5.1 34 5.5 5.1 2.3 1 1 0 1 1 1 0 WD domain, G-beta repeat RT_RNaseH_2 PF17919.1 GBG68847.1 - 2.7e-26 91.5 0.0 4.8e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68847.1 - 5.9e-25 87.6 0.0 1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68847.1 - 9e-12 44.9 0.1 2.1e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG68848.1 - 4.7e-25 87.5 0.0 3.2e-24 84.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68848.1 - 5e-20 71.8 0.0 1.8e-19 70.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68848.1 - 4.4e-14 52.5 0.0 7.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG68848.1 - 3.5e-05 24.0 0.0 0.00012 22.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG68848.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG68849.1 - 1.9e-28 98.4 0.0 3.6e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68849.1 - 2e-25 89.1 0.0 3.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68849.1 - 5.6e-05 22.7 0.1 8.2e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG68850.1 - 3.2e-15 56.3 0.0 3.4e-14 52.9 0.0 2.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG68850.1 - 2.8e-05 24.3 13.5 0.0038 17.5 0.0 5.1 5 0 0 5 5 5 2 Retrotransposon gag protein Nop14 PF04147.12 GBG68850.1 - 0.0022 16.3 19.2 0.0022 16.3 19.2 2.2 2 0 0 2 2 2 1 Nop14-like family RR_TM4-6 PF06459.12 GBG68850.1 - 0.0031 17.4 7.0 0.0031 17.4 7.0 2.7 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 Inhibitor_I29 PF08246.12 GBG68850.1 - 0.046 14.2 0.2 10 6.6 0.1 2.6 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) ZipA_C PF04354.13 GBG68850.1 - 0.056 13.3 0.4 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 ZipA, C-terminal FtsZ-binding domain Presenilin PF01080.17 GBG68850.1 - 5.7 5.6 22.6 0.028 13.2 3.3 2.3 2 0 0 2 2 2 0 Presenilin TRAP_alpha PF03896.16 GBG68850.1 - 8.8 5.4 17.9 0.015 14.5 6.7 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TPR_1 PF00515.28 GBG68851.1 - 1.5e-09 37.3 0.4 8.7e-06 25.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG68851.1 - 3.8e-07 29.7 0.4 0.00019 21.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG68851.1 - 0.00015 21.7 0.3 0.046 13.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 GBG68851.1 - 0.014 14.6 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Prefoldin_3 PF13758.6 GBG68851.1 - 0.018 15.1 0.8 2.3 8.3 0.4 2.1 2 0 0 2 2 2 0 Prefoldin subunit TPR_12 PF13424.6 GBG68851.1 - 0.033 14.5 0.1 0.08 13.2 0.1 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat UPF0122 PF04297.14 GBG68851.1 - 0.079 13.2 0.7 0.16 12.2 0.7 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like TPR_11 PF13414.6 GBG68851.1 - 0.081 12.6 0.1 0.29 10.8 0.1 2.0 2 0 0 2 2 2 0 TPR repeat TPR_9 PF13371.6 GBG68851.1 - 0.15 12.3 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG68851.1 - 0.16 12.8 0.1 0.38 11.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PolyA_pol PF01743.20 GBG68854.1 - 2.3e-20 73.3 6.2 2.5e-11 44.1 0.0 3.9 3 2 1 4 4 4 2 Poly A polymerase head domain gag-asp_proteas PF13975.6 GBG68854.1 - 9.1e-06 26.2 0.0 4.7e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68854.1 - 4.7e-05 24.0 0.0 0.00015 22.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease ADIP PF11559.8 GBG68854.1 - 0.00072 19.7 6.8 0.00072 19.7 6.8 2.5 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding RVP_2 PF08284.11 GBG68854.1 - 0.0013 18.5 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease PolyA_pol_RNAbd PF12627.7 GBG68854.1 - 0.0014 18.3 0.1 0.0014 18.3 0.1 2.1 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Retrotrans_gag PF03732.17 GBG68854.1 - 0.0029 17.8 0.1 0.0029 17.8 0.1 3.1 2 1 1 3 3 3 1 Retrotransposon gag protein Med4 PF10018.9 GBG68854.1 - 0.038 13.7 5.2 0.032 13.9 1.8 2.3 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2935 PF11155.8 GBG68854.1 - 0.28 11.5 2.2 0.79 10.1 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) HIP1_clath_bdg PF16515.5 GBG68854.1 - 4.1 8.1 14.0 0.028 15.0 4.3 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SPAR_C PF11881.8 GBG68854.1 - 4.2 7.2 15.3 3 7.7 1.4 3.3 2 1 1 3 3 3 0 C-terminal domain of SPAR protein FAD-oxidase_C PF02913.19 GBG68855.1 - 2.3e-56 191.2 0.0 3.1e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GBG68855.1 - 9.1e-37 125.9 0.4 1.6e-36 125.1 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Nop14 PF04147.12 GBG68856.1 - 4.8e-05 21.8 42.7 5.8e-05 21.5 42.7 1.3 1 0 0 1 1 1 1 Nop14-like family Presenilin PF01080.17 GBG68856.1 - 0.33 9.7 22.8 0.37 9.5 22.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 GBG68856.1 - 0.43 10.2 17.0 0.48 10.0 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.6 GBG68856.1 - 2.2 8.2 7.6 2.9 7.8 7.6 1.4 1 0 0 1 1 1 0 Protein Family FAM60A CDC27 PF09507.10 GBG68856.1 - 2.9 7.2 33.4 3.4 7.0 33.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.15 GBG68856.1 - 5.6 5.6 19.6 6.1 5.5 19.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 GBG68856.1 - 8 5.2 11.0 8.7 5.1 11.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 GBG68856.1 - 9.7 6.2 8.0 12 5.9 8.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2120 PF09893.9 GBG68857.1 - 0.23 11.6 3.8 0.15 12.2 1.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) CAAD PF14159.6 GBG68858.1 - 1e-30 105.4 0.0 1.5e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase HSBP1 PF06825.12 GBG68858.1 - 0.031 14.1 0.3 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF349 PF03993.12 GBG68858.1 - 1.1 9.6 4.3 3.3 8.1 1.9 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Ceramidase PF05875.12 GBG68859.1 - 8.4e-06 25.4 1.0 8.4e-06 25.4 1.0 1.9 2 1 0 2 2 2 1 Ceramidase DUF202 PF02656.15 GBG68859.1 - 0.12 12.8 6.3 0.26 11.8 2.1 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF202) 7TMR-DISM_7TM PF07695.11 GBG68859.1 - 0.17 11.7 14.2 0.031 14.2 7.2 2.4 1 1 1 2 2 2 0 7TM diverse intracellular signalling CAAD PF14159.6 GBG68861.1 - 1.1e-28 98.9 0.0 1.8e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3618 PF12277.8 GBG68861.1 - 0.013 15.7 0.1 1 9.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DUF3678 PF12435.8 GBG68861.1 - 0.032 13.6 2.4 0.032 13.6 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) AKNA PF12443.8 GBG68861.1 - 2.2 9.0 4.3 32 5.3 0.0 2.8 3 0 0 3 3 3 0 AT-hook-containing transcription factor zf-CCHC PF00098.23 GBG68862.1 - 6.5e-06 26.0 3.4 1.6e-05 24.8 3.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG68862.1 - 0.11 12.2 3.2 0.23 11.2 3.2 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger TolA_bind_tri PF16331.5 GBG68862.1 - 6.4 6.9 9.4 0.76 9.9 0.4 3.6 3 0 0 3 3 3 0 TolA binding protein trimerisation BAF1_ABF1 PF04684.13 GBG68863.1 - 0.3 10.1 12.0 0.03 13.4 3.8 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Menin PF05053.13 GBG68863.1 - 0.39 9.0 10.0 0.61 8.4 10.0 1.3 1 0 0 1 1 1 0 Menin Orf78 PF06024.12 GBG68863.1 - 4.2 7.7 8.7 7.3 7.0 1.3 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Myb_DNA-binding PF00249.31 GBG68864.1 - 5.9e-05 23.2 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain STAR_dimer PF16544.5 GBG68864.1 - 0.027 14.1 0.4 0.05 13.2 0.4 1.4 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein Transcrip_act PF04949.13 GBG68864.1 - 0.04 13.8 0.2 0.078 12.9 0.2 1.4 1 0 0 1 1 1 0 Transcriptional activator Voltage_CLC PF00654.20 GBG68865.1 - 7.9e-95 318.1 10.5 7.9e-95 318.1 10.5 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GBG68865.1 - 4.9e-10 39.7 0.4 1.8e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain Voltage_CLC PF00654.20 GBG68866.1 - 2.8e-24 86.0 1.8 3.5e-24 85.7 1.8 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel DUF659 PF04937.15 GBG68867.1 - 2.8e-38 131.2 0.0 7.7e-38 129.7 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG68867.1 - 0.13 12.2 22.3 0.036 13.9 3.3 3.9 3 0 0 3 3 3 0 AT hook motif RVT_1 PF00078.27 GBG68868.1 - 2.2e-27 96.0 0.1 5.5e-27 94.7 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68868.1 - 3.4e-16 59.4 0.0 8.3e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68868.1 - 3.1e-10 40.0 0.0 1e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG68868.1 - 8.6e-07 29.5 0.0 2.5e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68868.1 - 1.5e-05 25.5 0.0 4.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG68868.1 - 2.4e-05 24.1 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG68868.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG68868.1 - 0.005 17.1 0.0 0.005 17.1 0.0 4.4 4 1 0 4 4 3 1 Retrotransposon gag protein CPG4 PF15481.6 GBG68868.1 - 0.028 15.0 0.9 9.2 7.0 0.2 2.6 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 DUF2959 PF11172.8 GBG68868.1 - 0.082 13.0 7.7 0.96 9.6 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Mak10 PF04112.13 GBG68868.1 - 0.11 12.0 0.9 0.23 10.9 0.9 1.5 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Myb_DNA-bind_5 PF13873.6 GBG68868.1 - 0.14 12.2 2.8 15 5.8 0.1 3.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain AvrLm4-7 PF18661.1 GBG68868.1 - 0.2 12.7 4.3 6.7 7.8 0.7 2.9 2 0 0 2 2 2 0 Avirulence Effector AvrLm4-7 NikR_C PF08753.11 GBG68868.1 - 0.64 10.2 3.0 27 5.0 0.5 3.0 2 0 0 2 2 2 0 NikR C terminal nickel binding domain Voltage_CLC PF00654.20 GBG68869.1 - 8.8e-26 91.0 1.1 8.8e-26 91.0 1.1 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel RT_RNaseH_2 PF17919.1 GBG68870.1 - 1.7e-23 82.5 0.0 4.4e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68870.1 - 2.5e-21 75.9 0.0 5.3e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68870.1 - 7.9e-10 38.6 0.2 1.6e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Trans_reg_C PF00486.28 GBG68870.1 - 0.052 13.6 1.0 14 5.8 0.1 2.8 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal EzrA PF06160.12 GBG68871.1 - 0.0074 14.5 0.0 0.015 13.5 0.0 1.4 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Sigma54_CBD PF04963.13 GBG68871.1 - 0.036 13.9 0.1 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain Unstab_antitox PF09720.10 GBG68871.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative addiction module component Tektin PF03148.14 GBG68871.1 - 0.076 11.8 1.3 0.36 9.5 0.7 2.1 1 1 1 2 2 2 0 Tektin family DUF4094 PF13334.6 GBG68872.1 - 0.035 14.5 1.8 0.18 12.2 1.8 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Spectrin PF00435.21 GBG68872.1 - 0.14 12.6 13.2 0.073 13.6 7.3 3.1 2 0 0 2 2 2 0 Spectrin repeat DUF4407 PF14362.6 GBG68872.1 - 0.15 11.3 6.1 0.023 14.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 GBG68872.1 - 3.2 7.8 6.6 10 6.2 6.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SDA1 PF05285.12 GBG68875.1 - 0.016 14.6 13.8 0.016 14.7 13.8 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GBG68875.1 - 0.045 11.9 17.1 0.041 12.0 17.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 GBG68875.1 - 0.056 13.4 10.9 0.07 13.0 10.9 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 GBG68875.1 - 0.09 12.1 15.3 0.094 12.0 15.3 1.1 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 GBG68875.1 - 0.1 12.9 11.8 0.13 12.6 11.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 GBG68875.1 - 0.11 10.7 16.2 0.11 10.7 16.2 1.0 1 0 0 1 1 1 0 Nop14-like family Tom22 PF04281.13 GBG68875.1 - 0.14 11.9 5.8 0.23 11.2 5.8 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF4637 PF15470.6 GBG68875.1 - 0.25 11.1 12.4 0.37 10.5 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SpoIIP PF07454.11 GBG68875.1 - 0.36 10.2 7.0 0.33 10.4 7.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3535 PF12054.8 GBG68875.1 - 0.4 9.9 3.1 0.49 9.6 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) DUF4746 PF15928.5 GBG68875.1 - 0.45 9.9 10.7 0.44 9.9 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Tim54 PF11711.8 GBG68875.1 - 0.48 9.2 7.4 0.46 9.2 7.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 GBG68875.1 - 0.55 8.5 12.7 0.5 8.6 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 GBG68875.1 - 0.59 7.8 6.2 0.7 7.6 6.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Peptidase_S64 PF08192.11 GBG68875.1 - 0.96 7.9 3.0 0.99 7.8 3.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 GBG68875.1 - 1.5 7.5 5.4 1.3 7.7 5.4 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 GBG68875.1 - 1.7 7.3 6.6 1.7 7.3 6.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Inhibitor_I71 PF12628.7 GBG68875.1 - 1.8 8.3 5.0 3.1 7.6 3.9 1.7 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor NARP1 PF12569.8 GBG68875.1 - 2.1 7.1 10.8 2.2 7.1 10.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Afi1 PF07792.12 GBG68875.1 - 2.2 8.8 11.3 3.7 8.0 11.3 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Tho2 PF11262.8 GBG68875.1 - 3 6.9 6.4 3.8 6.6 6.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RNA_polI_A34 PF08208.11 GBG68875.1 - 3.4 7.7 17.1 1 9.4 14.7 1.4 2 0 0 2 2 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Zip PF02535.22 GBG68875.1 - 3.5 6.7 4.5 3.1 6.9 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3464 PF11947.8 GBG68875.1 - 3.9 7.2 7.1 5.7 6.7 7.1 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Sec62 PF03839.16 GBG68875.1 - 4 6.9 4.8 4.7 6.7 4.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_Rpc4 PF05132.14 GBG68875.1 - 4.7 7.6 11.9 1.1 9.7 8.9 1.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF913 PF06025.12 GBG68875.1 - 4.9 6.0 5.0 4.3 6.2 5.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 GBG68875.1 - 7.6 6.7 10.0 10 6.2 10.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PBP1_TM PF14812.6 GBG68875.1 - 8 6.9 14.4 2.5 8.5 11.5 1.7 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pec_lyase_C PF00544.19 GBG68876.1 - 1.7e-17 63.7 2.0 3.4e-15 56.2 2.0 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG68876.1 - 0.00012 22.0 13.2 0.001 18.9 13.2 2.2 1 1 0 1 1 1 1 Right handed beta helix region YjbF PF11102.8 GBG68876.1 - 0.12 12.1 0.2 4.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF RT_RNaseH PF17917.1 GBG68878.1 - 4.9e-13 49.3 0.0 1.1e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68878.1 - 6.9e-09 35.7 0.0 1.8e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG68879.1 - 4.2e-18 65.5 0.0 6.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68879.1 - 2.9e-07 30.3 0.0 1.9e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein RT_RNaseH_2 PF17919.1 GBG68881.1 - 2.9e-31 107.4 0.0 3.9e-30 103.8 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68881.1 - 1.5e-29 102.4 0.2 4.8e-29 100.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68881.1 - 1.5e-05 24.6 0.2 3.2e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CRISPR_Cse2 PF09485.10 GBG68881.1 - 0.1 13.1 0.2 0.1 13.1 0.2 2.5 2 1 1 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Phage_GPO PF05929.11 GBG68881.1 - 0.55 9.8 0.0 0.55 9.8 0.0 3.5 4 0 0 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase Presenilin PF01080.17 GBG68881.1 - 2.2 6.9 11.6 3.5 6.3 11.6 1.2 1 0 0 1 1 1 0 Presenilin DUF659 PF04937.15 GBG68882.1 - 2.3e-34 118.4 0.1 3.4e-34 117.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG68882.1 - 0.00056 19.6 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Transket_pyr PF02779.24 GBG68884.1 - 6.9e-43 146.4 0.3 1e-42 145.8 0.3 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 GBG68884.1 - 9.1e-41 139.9 0.9 5e-26 91.5 0.2 2.8 2 1 1 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 GBG68884.1 - 6.4e-31 106.8 0.0 1.3e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain SeleniumBinding PF11524.8 GBG68884.1 - 0.12 12.8 0.1 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Selenium binding protein Nop14 PF04147.12 GBG68885.1 - 0.013 13.7 8.7 0.015 13.5 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG68885.1 - 0.17 12.2 12.3 0.3 11.4 12.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 GBG68885.1 - 0.27 10.6 10.4 0.35 10.2 10.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG68885.1 - 0.67 8.2 9.0 0.84 7.8 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein D123 PF07065.14 GBG68885.1 - 0.93 8.6 4.1 1.4 8.0 4.1 1.2 1 0 0 1 1 1 0 D123 Cwf_Cwc_15 PF04889.12 GBG68885.1 - 3.3 7.4 12.3 4.9 6.8 12.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myb_DNA-bind_4 PF13837.6 GBG68887.1 - 1.7e-07 31.5 0.7 1.7e-07 31.5 0.7 2.9 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG68887.1 - 3.9e-05 23.7 0.9 0.00011 22.2 0.9 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF531 PF04407.12 GBG68887.1 - 0.06 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF531) DDE_Tnp_4 PF13359.6 GBG68888.1 - 2.3e-30 105.4 0.0 4.3e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68888.1 - 1.3e-16 60.8 0.0 2.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68888.1 - 3.2e-05 23.7 0.2 0.24 11.0 0.0 3.1 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG68888.1 - 0.017 15.5 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 Transposase DDE domain N6_N4_Mtase PF01555.18 GBG68889.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 DNA methylase Cytochrom_B561 PF03188.16 GBG68890.1 - 2.7e-36 124.7 2.2 2.7e-36 124.7 2.2 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2678 PF10856.8 GBG68890.1 - 0.063 13.2 2.2 0.075 13.0 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2678) Ferric_reduct PF01794.19 GBG68890.1 - 0.21 11.7 11.1 2.2 8.4 11.1 2.1 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF4079 PF13301.6 GBG68890.1 - 2.3 8.4 10.3 2.7 8.2 1.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 GBG68890.1 - 2.8 7.5 15.7 3.6 7.1 4.4 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Exostosin PF03016.15 GBG68892.1 - 1.1e-51 175.8 0.0 1.8e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Exostosin family RVT_1 PF00078.27 GBG68892.1 - 2.9e-06 27.0 0.1 6.7e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68893.1 - 8.3e-34 115.6 0.1 1.4e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68893.1 - 2.5e-31 108.1 0.0 5e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68894.1 - 6.5e-33 112.7 0.0 1.3e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68894.1 - 2.9e-28 98.2 0.0 5.5e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG68894.1 - 5.8e-28 97.9 0.0 1e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PaaX_C PF08223.11 GBG68894.1 - 0.034 14.4 0.1 0.13 12.5 0.1 2.0 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Integrase_H2C2 PF17921.1 GBG68894.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain Phage_GPO PF05929.11 GBG68894.1 - 0.12 12.0 0.2 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HalX PF08663.10 GBG68894.1 - 0.18 12.1 0.3 4.1 7.8 0.1 2.6 2 0 0 2 2 2 0 HalX domain CAP_N PF01213.19 GBG68894.1 - 5.2 6.5 5.9 11 5.4 5.9 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RCDG1 PF15725.5 GBG68894.1 - 8.6 6.9 12.0 25 5.4 12.0 1.8 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein SANT_DAMP1_like PF16282.5 GBG68895.1 - 3.8e-28 97.5 5.4 6.1e-28 96.8 5.4 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 GBG68895.1 - 2.1e-06 27.7 0.1 2.1e-06 27.7 0.1 2.5 3 0 0 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 GBG68895.1 - 0.00039 20.6 0.1 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GBG68895.1 - 0.0036 17.2 0.8 0.0079 16.1 0.6 1.7 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 GBG68895.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PIEZO PF15917.5 GBG68896.1 - 2.2 7.7 13.1 2.1 7.8 3.5 2.2 2 0 0 2 2 2 0 Piezo Myb_DNA-bind_4 PF13837.6 GBG68897.1 - 2.5e-08 34.2 1.2 5.4e-08 33.1 0.3 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG68897.1 - 0.0001 22.5 0.1 0.00025 21.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG68897.1 - 0.082 13.0 3.6 0.11 12.6 2.0 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG68897.1 - 0.14 12.5 0.5 0.27 11.5 0.5 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG68898.1 - 2.5e-18 66.2 0.0 6.3e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG68898.1 - 2.8e-08 33.6 0.0 4.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG68898.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Methyltransf_7 PF03492.15 GBG68899.1 - 1.1e-63 215.4 0.0 6.7e-56 189.9 0.0 2.3 2 0 0 2 2 2 2 SAM dependent carboxyl methyltransferase RelE PF06296.12 GBG68899.1 - 0.012 15.8 0.3 0.033 14.3 0.3 1.7 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system DUF659 PF04937.15 GBG68900.1 - 2.7e-11 43.5 0.0 4.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG68900.1 - 0.00086 19.1 0.8 0.0022 17.7 0.8 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG68903.1 - 1.9e-14 53.8 0.2 3.1e-14 53.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG68904.1 - 3.4e-07 30.0 2.7 3.4e-07 30.0 2.7 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG68904.1 - 0.0013 18.5 1.1 0.0028 17.4 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG68904.1 - 0.94 9.2 6.1 0.22 11.3 2.2 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Methyltransf_7 PF03492.15 GBG68906.1 - 2.2e-65 221.1 0.0 8e-57 192.9 0.0 2.4 2 0 0 2 2 2 2 SAM dependent carboxyl methyltransferase Ins134_P3_kin PF05770.11 GBG68908.1 - 8.3e-25 87.5 0.0 5.5e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain PTP_tm PF18861.1 GBG68909.1 - 0.1 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Myb_DNA-bind_4 PF13837.6 GBG68913.1 - 4.8e-06 26.9 1.8 8e-06 26.2 0.3 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG68913.1 - 0.018 15.4 0.3 0.046 14.0 0.1 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Diphthami_syn_2 PF01902.17 GBG68914.1 - 2.9e-42 144.6 0.4 6.7e-42 143.5 0.0 1.8 2 1 0 2 2 2 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 GBG68914.1 - 2.1e-21 76.2 0.0 3.1e-09 36.9 0.0 4.0 3 1 0 3 3 3 2 Endoribonuclease L-PSP SpoVS PF04232.12 GBG68914.1 - 0.52 10.1 2.3 4.7 7.0 0.1 3.0 3 0 0 3 3 3 0 Stage V sporulation protein S (SpoVS) E7 PF00527.18 GBG68914.1 - 2.3 8.5 5.7 56 4.0 3.4 3.3 2 1 1 3 3 3 0 E7 protein, Early protein Methyltransf_25 PF13649.6 GBG68915.1 - 1.4e-08 35.3 0.0 3.2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG68915.1 - 1.1e-06 29.2 0.0 2.9e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GBG68915.1 - 1.1e-06 28.3 0.1 1.1e-06 28.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GBG68915.1 - 2.2e-05 24.1 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 GBG68915.1 - 0.00012 22.0 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 GBG68915.1 - 0.00069 19.5 0.0 0.00069 19.5 0.0 2.6 2 1 0 2 2 1 1 Methyltransferase domain Met_10 PF02475.16 GBG68915.1 - 0.0011 18.7 0.1 0.0018 18.0 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 GBG68915.1 - 0.0028 18.3 1.6 0.0072 17.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 GBG68915.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 GBG68915.1 - 0.027 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 GBG68915.1 - 0.029 14.4 9.9 0.053 13.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Rsm22 PF09243.10 GBG68915.1 - 0.038 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 CCDC53 PF10152.9 GBG68915.1 - 0.045 14.2 6.3 0.087 13.2 6.3 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Connexin PF00029.19 GBG68915.1 - 0.068 12.9 2.4 0.13 12.0 2.4 1.4 1 0 0 1 1 1 0 Connexin DDHD PF02862.17 GBG68915.1 - 0.068 13.3 4.5 0.14 12.3 4.5 1.5 1 0 0 1 1 1 0 DDHD domain Methyltransf_31 PF13847.6 GBG68915.1 - 0.069 12.9 0.0 0.069 12.9 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 GBG68915.1 - 0.069 13.1 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain CPSF100_C PF13299.6 GBG68915.1 - 0.077 13.2 2.1 0.14 12.3 2.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3464 PF11947.8 GBG68915.1 - 0.11 12.2 7.8 0.22 11.3 7.8 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 U3_snoRNA_assoc PF08297.11 GBG68915.1 - 0.18 12.6 5.0 0.4 11.4 5.0 1.5 1 0 0 1 1 1 0 U3 snoRNA associated DUF5427 PF10310.9 GBG68915.1 - 0.2 10.6 12.9 0.33 9.9 12.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PAT1 PF09770.9 GBG68915.1 - 0.2 9.9 20.1 0.27 9.5 20.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.6 GBG68915.1 - 0.21 10.9 5.1 0.32 10.3 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SpoIIP PF07454.11 GBG68915.1 - 0.28 10.6 8.3 0.45 9.9 8.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Suf PF05843.14 GBG68915.1 - 0.33 10.9 11.3 0.55 10.2 11.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 GBG68915.1 - 0.34 10.9 4.9 0.27 11.3 2.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PRMT5_C PF17286.2 GBG68915.1 - 0.37 10.6 2.8 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 PRMT5 oligomerisation domain RPA43_OB PF17875.1 GBG68915.1 - 0.38 11.4 10.6 1.2 9.8 10.6 1.8 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Cons_hypoth95 PF03602.15 GBG68915.1 - 0.44 10.2 0.0 0.44 10.2 0.0 1.9 2 0 0 2 2 1 0 Conserved hypothetical protein 95 EIIBC-GUT_N PF03612.14 GBG68915.1 - 0.86 9.3 7.6 1.7 8.4 7.6 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TRM13 PF05206.14 GBG68915.1 - 0.89 9.0 8.7 1.8 8.0 7.3 1.9 2 0 0 2 2 2 0 Methyltransferase TRM13 CobT PF06213.12 GBG68915.1 - 1 8.7 15.7 1.7 7.9 15.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2722 PF10846.8 GBG68915.1 - 1.7 7.5 28.2 3.5 6.5 28.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 GBG68915.1 - 2 7.1 12.2 0.98 8.1 9.9 1.6 2 0 0 2 2 2 0 Presenilin Ndc1_Nup PF09531.10 GBG68915.1 - 2.4 6.8 8.7 3.4 6.2 8.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 GBG68915.1 - 3.4 7.4 8.0 5.8 6.6 8.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RR_TM4-6 PF06459.12 GBG68915.1 - 3.5 7.4 8.7 6.5 6.5 8.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 GBG68915.1 - 4.1 6.3 16.5 8.7 5.2 16.5 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 GBG68915.1 - 4.4 7.3 19.1 8.6 6.4 19.1 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Lin-8 PF03353.15 GBG68915.1 - 4.5 6.7 14.7 7.5 6.0 14.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 GBG68915.1 - 7.1 4.4 9.6 10 3.9 9.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3408 PF11888.8 GBG68915.1 - 7.8 6.6 11.8 16 5.6 11.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Retrotrans_gag PF03732.17 GBG68917.1 - 0.016 15.4 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein LRAT PF04970.13 GBG68918.1 - 1.9e-23 83.2 0.3 2.3e-11 44.1 0.1 2.3 2 0 0 2 2 2 2 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 GBG68918.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 NlpC/P60 family GHMP_kinases_N PF00288.26 GBG68919.1 - 2.7e-09 37.1 0.0 6.4e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GBG68919.1 - 0.015 15.6 0.0 0.056 13.8 0.1 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal YchF-GTPase_C PF06071.13 GBG68919.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF933) GIY-YIG PF01541.24 GBG68920.1 - 0.00012 22.3 0.0 0.00012 22.3 0.0 2.2 2 0 0 2 2 2 1 GIY-YIG catalytic domain DUF4228 PF14009.6 GBG68920.1 - 0.15 12.4 4.7 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Methyltransf_16 PF10294.9 GBG68921.1 - 2e-26 92.8 0.1 4.4e-24 85.1 0.1 3.2 3 0 0 3 3 3 1 Lysine methyltransferase Pyr_redox PF00070.27 GBG68921.1 - 0.12 13.0 4.3 0.47 11.0 0.1 3.5 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RT_RNaseH_2 PF17919.1 GBG68922.1 - 8.4e-26 89.9 0.0 1.4e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68922.1 - 1.3e-23 83.3 0.0 2e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG68922.1 - 6.7 4.9 10.1 2.8 6.1 8.0 1.4 2 0 0 2 2 2 0 CDC45-like protein CHASE3 PF05227.13 GBG68923.1 - 0.042 13.8 1.2 0.5 10.3 0.0 2.1 1 1 1 2 2 2 0 CHASE3 domain HSP70 PF00012.20 GBG68925.1 - 2.4e-132 442.2 0.0 2.8e-132 441.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG68925.1 - 1e-12 47.5 0.1 1.3e-11 43.9 0.0 2.4 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG68925.1 - 0.00011 22.0 0.0 0.00027 20.7 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2237 PF09996.9 GBG68926.1 - 1.6e-51 173.1 0.0 2.1e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) YjbE PF11106.8 GBG68926.1 - 0.15 12.2 8.9 0.21 11.8 0.9 2.3 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE FDF PF09532.10 GBG68928.1 - 0.18 12.7 3.6 0.25 12.2 3.6 1.2 1 0 0 1 1 1 0 FDF domain Trypsin PF00089.26 GBG68929.1 - 9.6e-32 110.6 0.0 1.4e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin RT_RNaseH_2 PF17919.1 GBG68931.1 - 5.2e-22 77.8 0.0 1e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68931.1 - 6e-19 68.3 0.0 1.4e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG68931.1 - 8.1e-15 55.1 0.0 1.7e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG68931.1 - 8e-14 51.5 0.2 2.3e-13 50.0 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG68931.1 - 3.9e-11 42.9 0.0 6.1e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG68931.1 - 0.0082 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVP PF00077.20 GBG68931.1 - 0.011 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG68931.1 - 0.13 12.8 0.1 0.41 11.2 0.1 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HSP70 PF00012.20 GBG68932.1 - 5e-160 533.6 0.0 1.5e-90 304.1 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG68932.1 - 8.9e-13 47.7 1.0 0.00054 18.9 0.0 4.4 4 1 0 4 4 4 3 MreB/Mbl protein FtsA PF14450.6 GBG68932.1 - 0.00028 21.2 0.3 2.9 8.4 0.0 3.6 2 2 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.16 GBG68932.1 - 0.0006 19.6 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Raco_middle PF17651.1 GBG68932.1 - 0.12 12.1 0.1 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 RACo middle region B12D PF06522.11 GBG68933.1 - 6.2e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RVT_1 PF00078.27 GBG68934.1 - 4.2e-30 104.9 0.1 6.3e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG68934.1 - 1.3e-16 60.4 0.3 3.5e-16 59.0 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68934.1 - 2.8e-09 37.2 0.0 5.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG68934.1 - 0.00018 21.3 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG68934.1 - 0.004 17.3 0.1 0.011 16.0 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG68935.1 - 1.3e-32 111.8 0.1 2.2e-32 111.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68935.1 - 1.5e-30 105.5 0.0 2.6e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ZapB PF06005.12 GBG68936.1 - 0.0055 17.1 2.2 0.079 13.4 0.4 2.4 2 0 0 2 2 2 1 Cell division protein ZapB KLRAQ PF10205.9 GBG68936.1 - 0.075 13.3 3.9 0.23 11.7 0.0 2.6 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein RVT_1 PF00078.27 GBG68938.1 - 2.2e-27 96.0 0.0 3.9e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68938.1 - 1.3e-12 47.6 0.0 3.8e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68938.1 - 0.001 19.3 0.0 0.0034 17.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG68938.1 - 0.029 14.6 0.7 0.47 10.8 0.0 3.4 4 0 0 4 4 4 0 Retrotransposon gag protein AIF-MLS PF14962.6 GBG68938.1 - 0.033 14.2 5.6 0.068 13.1 5.6 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF659 PF04937.15 GBG68939.1 - 1.6e-10 41.1 0.3 6.4e-08 32.6 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG68939.1 - 0.0068 16.2 2.7 0.033 14.0 2.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Tho2 PF11262.8 GBG68939.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RVT_1 PF00078.27 GBG68940.1 - 1.8e-26 93.0 0.1 3.9e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68940.1 - 1.1e-07 31.8 0.0 3.7e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG68940.1 - 0.0015 18.7 0.7 0.011 16.0 0.1 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein AIP3 PF03915.13 GBG68940.1 - 0.021 14.0 1.9 0.033 13.3 1.9 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 DUF3499 PF12005.8 GBG68940.1 - 8.2 7.0 8.0 2.8 8.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) RVT_1 PF00078.27 GBG68941.1 - 8.6e-36 123.5 0.1 1.6e-35 122.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68941.1 - 1.9e-14 53.5 0.0 5.3e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG68941.1 - 6.7e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG68941.1 - 0.00058 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG68941.1 - 0.00092 19.8 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68941.1 - 0.0037 17.8 0.0 0.01 16.4 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG68941.1 - 0.054 13.3 0.1 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative peptidase (DUF1758) HALZ PF02183.18 GBG68942.1 - 0.0028 17.8 0.8 0.0073 16.5 0.8 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper CCD48 PF15799.5 GBG68942.1 - 0.034 12.5 0.5 0.05 11.9 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 bZIP_1 PF00170.21 GBG68942.1 - 0.037 14.1 1.0 0.086 12.9 1.0 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF848 PF05852.11 GBG68942.1 - 0.052 13.7 0.9 0.1 12.7 0.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) YabA PF06156.13 GBG68942.1 - 0.16 12.6 0.1 1.2 9.8 0.0 2.2 2 0 0 2 2 2 0 Initiation control protein YabA GvpL_GvpF PF06386.11 GBG68942.1 - 0.78 9.6 4.8 1.3 8.9 4.8 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.15 GBG68942.1 - 1.3 9.1 5.4 0.35 11.0 1.3 2.1 2 0 0 2 2 2 0 Basic region leucine zipper eIF2_C PF09173.11 GBG68943.1 - 1.1e-35 121.8 0.6 2.8e-35 120.4 0.6 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 GBG68943.1 - 7e-24 84.4 0.4 5.5e-23 81.5 0.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GBG68943.1 - 1.3e-10 41.5 0.4 3.2e-10 40.3 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG68943.1 - 0.0058 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG68943.1 - 0.015 15.2 0.3 0.2 11.5 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 GBG68943.1 - 0.036 14.1 0.1 0.1 12.6 0.1 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FHA PF00498.26 GBG68944.1 - 1.9e-19 69.8 0.1 2.6e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GBG68944.1 - 8.4e-12 45.2 0.1 1.1e-11 44.9 0.1 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 GBG68944.1 - 0.043 14.0 0.0 0.057 13.7 0.0 1.1 1 0 0 1 1 1 0 FHA domain gag-asp_proteas PF13975.6 GBG68945.1 - 0.038 14.6 0.1 0.15 12.7 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68945.1 - 0.11 13.1 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease TGS PF02824.21 GBG68946.1 - 2.9e-13 49.7 0.0 5.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 GBG68946.1 - 1.6e-11 44.3 0.2 4.8e-11 42.7 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG68946.1 - 3.5e-07 29.9 0.0 4.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 GBG68946.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MeaB PF03308.16 GBG68946.1 - 0.0011 18.0 0.1 0.0018 17.3 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 GBG68946.1 - 0.069 13.7 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter KTI12 PF08433.10 GBG68946.1 - 0.13 11.7 0.0 0.4 10.1 0.0 1.7 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Dynamin_N PF00350.23 GBG68946.1 - 0.16 12.0 2.6 0.17 12.0 0.3 2.0 2 1 1 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 GBG68946.1 - 0.17 11.7 0.1 0.44 10.4 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase Dimer_Tnp_hAT PF05699.14 GBG68947.1 - 0.00014 21.6 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region tRNA-synt_1b PF00579.25 GBG68948.1 - 1.5e-47 162.4 0.0 2.1e-38 132.3 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) PLDc PF00614.22 GBG68949.1 - 1.8e-20 72.2 3.2 2.2e-10 40.3 0.3 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG68949.1 - 2.8e-16 59.6 0.1 3e-10 40.1 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain DUF4813 PF16072.5 GBG68949.1 - 5.6e-05 23.0 4.8 5.6e-05 23.0 4.8 7.0 6 2 1 7 7 7 1 Domain of unknown function (DUF4813) RT_RNaseH_2 PF17919.1 GBG68950.1 - 1.1e-25 89.6 0.0 3.7e-25 87.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68950.1 - 2.7e-23 82.2 0.0 6.7e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG68950.1 - 0.046 14.0 0.2 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2781 PF10914.8 GBG68950.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Longin PF13774.6 GBG68950.1 - 0.19 11.8 1.6 2.3 8.3 0.1 2.8 3 0 0 3 3 3 0 Regulated-SNARE-like domain CLZ PF16526.5 GBG68950.1 - 0.21 11.9 1.5 0.37 11.2 0.5 1.9 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PurA PF04845.13 GBG68951.1 - 4.2e-37 127.6 0.0 1.9e-22 79.7 0.0 2.3 2 0 0 2 2 2 2 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 GBG68951.1 - 0.00021 21.4 0.9 2.4 8.3 0.1 3.4 3 1 0 3 3 3 3 Protein of unknown function (DUF3276) DUF5506 PF17611.2 GBG68951.1 - 0.078 12.9 0.0 26 4.7 0.0 3.0 2 1 0 3 3 3 0 Family of unknown function (DUF5506) PUD PF03714.14 GBG68956.1 - 2.6e-05 25.0 0.0 0.54 11.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial pullanase-associated domain DAO_C PF16901.5 GBG68956.1 - 0.0011 18.8 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 C-terminal domain of alpha-glycerophosphate oxidase ADH_zinc_N_2 PF13602.6 GBG68956.1 - 0.0064 17.5 0.0 8.6 7.4 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase INSIG PF07281.12 GBG68956.1 - 0.011 15.4 0.3 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) CBM_14 PF01607.24 GBG68956.1 - 0.021 14.9 1.6 8.3 6.7 0.1 2.9 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain SepF PF04472.12 GBG68956.1 - 0.05 13.9 0.0 18 5.7 0.0 2.5 2 0 0 2 2 2 0 Cell division protein SepF RasGEF_N PF00618.20 GBG68956.1 - 0.11 12.7 0.1 31 4.8 0.0 2.6 2 0 0 2 2 2 0 RasGEF N-terminal motif DUF5633 PF18656.1 GBG68956.1 - 0.47 10.4 4.8 13 5.7 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Ribosomal_L21e PF01157.18 GBG68957.1 - 5.8e-45 151.3 2.1 8.2e-45 150.8 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e SepSecS PF05889.13 GBG68957.1 - 0.068 11.9 0.1 0.088 11.5 0.1 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS zf_C2H2_ZHX PF18387.1 GBG68957.1 - 0.2 11.3 0.5 4.9 6.9 0.2 2.2 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Rhomboid PF01694.22 GBG68958.1 - 1.1e-24 87.1 16.3 2.1e-24 86.2 16.3 1.5 1 0 0 1 1 1 1 Rhomboid family COX7C PF02935.16 GBG68959.1 - 4.3e-07 30.1 0.2 8.2e-07 29.2 0.2 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Archaeal_AmoA PF12942.7 GBG68959.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) NDUF_B12 PF08122.12 GBG68959.1 - 0.35 10.9 1.5 0.55 10.3 0.7 1.7 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF2301 PF10063.9 GBG68960.1 - 5.4e-50 169.3 2.2 8e-50 168.8 2.2 1.3 1 0 0 1 1 1 1 Uncharacterized integral membrane protein (DUF2301) PAP2_3 PF14378.6 GBG68960.1 - 0.017 14.8 0.9 0.031 14.0 0.9 1.4 1 0 0 1 1 1 0 PAP2 superfamily Nbl1_Borealin_N PF10444.9 GBG68961.1 - 0.0004 19.9 0.2 0.00059 19.4 0.2 1.2 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Pox_P4A PF03395.14 GBG68961.1 - 0.017 12.7 0.1 0.02 12.5 0.1 1.0 1 0 0 1 1 1 0 Poxvirus P4A protein zf-RVT PF13966.6 GBG68962.1 - 2e-05 25.2 2.8 2e-05 25.2 2.8 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF4813 PF16072.5 GBG68963.1 - 0.53 9.9 4.3 0.8 9.3 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) zf-CCHC PF00098.23 GBG68964.1 - 6.2e-09 35.5 3.3 9.6e-09 34.9 3.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG68964.1 - 0.18 11.6 1.4 0.33 10.7 1.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Ribosomal_L37ae PF01780.19 GBG68964.1 - 0.52 10.4 4.9 0.48 10.6 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L37ae protein family RVT_1 PF00078.27 GBG68965.1 - 1.5e-10 40.9 0.1 4.8e-10 39.3 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG68965.1 - 0.002 17.9 0.0 0.0058 16.4 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG68965.1 - 0.014 16.0 0.1 0.044 14.3 0.1 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68965.1 - 0.029 15.0 0.1 0.073 13.7 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG68965.1 - 0.042 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG68966.1 - 0.003 17.8 3.2 0.0077 16.5 3.2 1.6 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 GBG68966.1 - 0.061 13.4 5.6 0.17 11.9 5.6 1.8 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TEX19 PF15553.6 GBG68966.1 - 0.55 10.2 3.6 0.53 10.2 1.3 2.2 2 1 0 2 2 2 0 Testis-expressed protein 19 RT_RNaseH PF17917.1 GBG68967.1 - 1.7e-21 76.4 0.0 1.3e-20 73.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68967.1 - 9.5e-20 70.5 0.0 4e-19 68.5 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68967.1 - 1.3e-13 50.8 0.3 3.2e-13 49.6 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68967.1 - 2e-12 47.3 0.0 2.2e-11 44.0 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain CENP-N PF05238.13 GBG68967.1 - 2.2 7.5 4.3 4.1 6.6 4.3 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Methyltransf_11 PF08241.12 GBG68968.1 - 3.9e-09 37.0 0.0 9.7e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG68968.1 - 1.1e-06 29.2 0.0 2.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 GBG68968.1 - 2.7e-06 28.1 6.5 1.3e-05 25.9 6.5 2.2 1 1 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_23 PF13489.6 GBG68968.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GBG68968.1 - 0.018 15.8 0.0 0.041 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GBG68968.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 GBG68968.1 - 0.18 11.5 0.0 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 DNA methylase RVT_1 PF00078.27 GBG68969.1 - 6e-38 130.6 5.5 6.9e-27 94.4 0.1 3.4 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68969.1 - 2.2e-18 66.2 0.1 1.3e-15 57.2 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Radical_SAM PF04055.21 GBG68969.1 - 2.2e-18 67.2 0.3 1.2e-09 38.7 0.0 2.5 2 0 0 2 2 2 2 Radical SAM superfamily UPF0004 PF00919.20 GBG68969.1 - 1.3e-17 63.7 1.9 2.6e-17 62.6 0.1 2.6 3 0 0 3 3 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 GBG68969.1 - 4.2e-13 49.1 0.5 8.4e-13 48.1 0.5 1.5 1 0 0 1 1 1 1 TRAM domain RVP_2 PF08284.11 GBG68969.1 - 4.2e-12 46.0 0.0 7.6e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG68969.1 - 5e-08 33.2 0.0 4e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG68969.1 - 1.1e-07 32.4 0.0 1.9e-06 28.4 0.0 2.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68969.1 - 3e-06 27.7 0.0 5.1e-05 23.8 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG68969.1 - 0.00026 20.8 0.0 0.00061 19.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG68969.1 - 0.00055 19.7 0.0 0.012 15.4 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease TRAM_2 PF18693.1 GBG68969.1 - 0.024 14.8 1.3 0.045 13.9 0.2 2.1 2 0 0 2 2 2 0 TRAM domain Retrotrans_gag PF03732.17 GBG68969.1 - 0.11 12.8 0.3 0.75 10.1 0.1 2.6 2 0 0 2 2 1 0 Retrotransposon gag protein DUF16 PF01519.16 GBG68969.1 - 0.2 12.2 0.6 1.2 9.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 SARAF PF06682.12 GBG68970.1 - 0.0039 16.9 0.4 0.0039 16.9 0.4 3.1 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis CitMHS PF03600.16 GBG68970.1 - 0.0071 15.6 23.4 0.0093 15.2 23.4 1.3 1 0 0 1 1 1 1 Citrate transporter SelK_SelG PF10961.8 GBG68970.1 - 0.11 13.1 12.5 0.25 12.0 12.5 1.9 1 1 0 1 1 1 0 Selenoprotein SelK_SelG RT_RNaseH_2 PF17919.1 GBG68971.1 - 7.1e-23 80.5 0.0 1.6e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rubis-subs-bind PF09273.11 GBG68971.1 - 5.4e-20 72.4 0.1 1.7e-19 70.8 0.1 1.9 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding RVT_1 PF00078.27 GBG68971.1 - 2.6e-19 69.6 0.0 6.5e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG68971.1 - 1.1e-14 54.6 0.0 4.1e-14 52.8 0.0 2.0 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase DUF4187 PF13821.6 GBG68971.1 - 0.0022 17.7 1.1 0.0059 16.4 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG68971.1 - 0.018 15.3 1.3 0.038 14.3 0.1 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein GCIP PF13324.6 GBG68971.1 - 0.11 12.0 3.6 0.34 10.5 3.6 1.8 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GBG68971.1 - 0.16 10.0 17.9 0.25 9.4 17.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 GBG68971.1 - 0.18 11.8 1.9 0.66 10.0 1.9 2.0 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.8 GBG68971.1 - 0.25 11.6 12.1 0.53 10.5 12.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 GBG68971.1 - 2.4 6.3 11.7 3.5 5.7 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 GBG68971.1 - 6.1 5.3 10.1 10 4.6 10.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cnd2 PF05786.14 GBG68971.1 - 7.2 5.1 11.6 11 4.5 11.6 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF2457 PF10446.9 GBG68971.1 - 7.9 5.5 24.9 15 4.6 24.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RT_RNaseH PF17917.1 GBG68973.1 - 7.6e-21 74.4 0.0 2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68973.1 - 3.6e-20 71.8 0.0 8.5e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG68973.1 - 5.8e-07 30.0 0.4 1.9e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG68973.1 - 0.00039 21.0 0.3 0.0019 18.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG68973.1 - 0.012 15.4 0.9 0.023 14.5 0.9 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG68973.1 - 0.044 14.0 0.1 0.22 11.8 0.1 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein SICA_C PF12879.7 GBG68973.1 - 0.16 12.0 1.4 0.51 10.4 1.4 1.9 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain RXLR PF16810.5 GBG68973.1 - 0.21 12.0 3.7 1.9 8.9 0.8 2.7 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Lamprin PF06403.11 GBG68973.1 - 2 8.4 5.2 4.1 7.4 5.2 1.4 1 0 0 1 1 1 0 Lamprin Integrase_H2C2 PF17921.1 GBG68974.1 - 2.4e-08 33.9 0.0 7.4e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG68974.1 - 1.3e-07 31.4 0.0 3.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG68974.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain SpoIIE PF07228.12 GBG68976.1 - 6.1e-15 55.6 0.1 1e-14 54.9 0.1 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GBG68976.1 - 4.5e-08 33.0 4.0 0.00027 20.7 0.0 2.9 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 GBG68976.1 - 0.00017 21.3 0.5 0.002 17.8 0.5 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C Peptidase_M18 PF02127.15 GBG68976.1 - 0.031 13.1 0.6 0.053 12.3 0.6 1.2 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) PDGF_N PF04692.13 GBG68976.1 - 0.62 10.9 6.3 2.1 9.2 6.3 1.9 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region Pox_F17 PF04767.12 GBG68976.1 - 0.68 10.5 2.8 1.4 9.5 1.1 2.4 2 1 1 3 3 3 0 DNA-binding 11 kDa phosphoprotein Androgen_recep PF02166.16 GBG68976.1 - 1.6 7.5 17.4 0.096 11.5 11.8 1.6 1 1 0 1 1 1 0 Androgen receptor Pkinase_Tyr PF07714.17 GBG68978.1 - 2e-43 148.6 0.0 3.1e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG68978.1 - 4.1e-39 134.5 0.0 6.4e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Malectin_like PF12819.7 GBG68978.1 - 1.7e-15 57.0 0.0 2.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Malectin-like domain Malectin PF11721.8 GBG68978.1 - 3.1e-12 46.9 0.0 4.6e-07 30.1 0.0 2.9 2 1 0 2 2 2 2 Malectin domain LRR_8 PF13855.6 GBG68978.1 - 3.3e-06 26.8 0.1 6.1e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GBG68978.1 - 0.00013 22.3 0.2 0.00032 21.0 0.2 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) ABC1 PF03109.16 GBG68978.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GBG68978.1 - 0.0075 16.2 0.0 0.03 14.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family DAG_kinase_N PF14513.6 GBG68978.1 - 0.034 14.4 0.2 0.097 12.9 0.0 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus PIP49_C PF12260.8 GBG68978.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 CobT PF06213.12 GBG68979.1 - 0.32 10.3 22.8 0.33 10.3 22.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 GBG68979.1 - 0.56 8.2 45.7 0.74 7.8 45.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG68979.1 - 0.8 7.9 28.2 0.94 7.7 28.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG68979.1 - 0.93 7.6 34.9 0.92 7.6 34.9 1.0 1 0 0 1 1 1 0 Nop14-like family Oleosin PF01277.17 GBG68980.1 - 6.1e-09 35.6 11.9 6.1e-09 35.6 11.9 2.1 2 1 0 2 2 2 1 Oleosin DUF2048 PF09752.9 GBG68980.1 - 0.082 12.0 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 FtsX PF02687.21 GBG68980.1 - 0.12 12.8 9.6 0.21 12.1 9.6 1.4 1 0 0 1 1 1 0 FtsX-like permease family ABC2_membrane_3 PF12698.7 GBG68980.1 - 0.13 11.3 8.1 0.17 10.9 8.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Spc7 PF08317.11 GBG68981.1 - 0.0097 14.8 67.1 0.067 12.1 5.6 4.8 1 1 2 4 4 4 3 Spc7 kinetochore protein ARTD15_N PF18084.1 GBG68981.1 - 0.33 11.2 3.9 27 5.1 0.1 4.6 3 1 1 4 4 4 0 ARTD15 N-terminal domain Filament PF00038.21 GBG68981.1 - 0.61 9.6 48.4 0.77 9.3 34.6 3.1 1 1 1 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.11 GBG68981.1 - 3.8 8.0 23.2 11 6.5 1.8 7.2 4 2 3 7 7 7 0 Flagella accessory protein C (FlaC) WD40_alt PF14077.6 GBG68981.1 - 5.3 7.0 8.5 5.5 6.9 0.7 4.2 3 1 1 4 4 4 0 Alternative WD40 repeat motif DUF616 PF04765.13 GBG68982.1 - 4.2e-120 400.7 0.0 5.5e-120 400.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF616) ETS_PEA3_N PF04621.13 GBG68983.1 - 0.017 15.0 0.6 0.017 15.0 0.6 1.5 2 0 0 2 2 2 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Retrotrans_gag PF03732.17 GBG68986.1 - 0.006 16.8 0.1 0.021 15.1 0.0 2.1 1 1 0 1 1 1 1 Retrotransposon gag protein ABC_tran PF00005.27 GBG68989.1 - 2.7e-23 83.0 0.0 5.8e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG68989.1 - 7.4e-10 39.1 0.0 7.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GBG68989.1 - 6.7e-05 22.4 0.2 0.31 10.5 0.0 2.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GBG68989.1 - 0.0029 18.1 0.1 0.0078 16.7 0.1 1.6 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 GBG68989.1 - 0.0045 16.9 0.1 0.012 15.6 0.1 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 GBG68989.1 - 0.0047 17.4 0.3 0.037 14.5 0.0 2.4 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 GBG68989.1 - 0.0059 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG68989.1 - 0.0061 17.0 0.2 0.022 15.2 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG68989.1 - 0.0098 16.2 0.0 0.028 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GBG68989.1 - 0.01 15.8 0.1 0.035 14.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 GBG68989.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 GBG68989.1 - 0.011 15.7 0.0 0.92 9.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG68989.1 - 0.029 13.9 0.4 0.076 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain MutS_V PF00488.21 GBG68989.1 - 0.055 13.5 0.1 7.2 6.6 0.0 2.2 2 0 0 2 2 2 0 MutS domain V RsgA_GTPase PF03193.16 GBG68989.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 GBG68989.1 - 0.061 12.7 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CAP_N PF01213.19 GBG68989.1 - 0.062 12.8 2.2 0.087 12.3 2.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_27 PF13514.6 GBG68989.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 GBG68989.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 GBG68989.1 - 0.078 13.1 0.5 0.14 12.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 GBG68989.1 - 0.087 13.4 0.0 0.34 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GBG68989.1 - 0.094 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Acyl_transf_1 PF00698.21 GBG68989.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 1 0 Acyl transferase domain AAA_28 PF13521.6 GBG68989.1 - 0.15 12.3 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Chorion_2 PF03964.15 GBG68989.1 - 0.17 12.7 13.1 0.29 12.0 12.1 1.8 1 1 0 1 1 1 0 Chorion family 2 Asp_protease_2 PF13650.6 GBG68990.1 - 2.6e-07 31.2 0.1 4.8e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG68990.1 - 1.9e-06 28.3 1.0 7.5e-06 26.4 0.4 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG68990.1 - 0.0013 18.6 0.1 0.002 17.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG68990.1 - 0.015 15.3 2.9 0.027 14.6 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle TMEM208_SND2 PF05620.11 GBG68991.1 - 1.3e-48 164.9 0.1 1.5e-48 164.7 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Meiotic_rec114 PF03525.14 GBG68992.1 - 0.011 14.8 2.1 0.013 14.5 2.1 1.1 1 0 0 1 1 1 0 Meiotic recombination protein rec114 SBE2 PF17076.5 GBG68992.1 - 1.4 7.1 6.8 1.4 7.0 6.8 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation AAA PF00004.29 GBG68993.1 - 3.6e-39 134.2 0.0 6.3e-37 127.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GBG68993.1 - 2.6e-05 24.0 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GBG68993.1 - 0.00015 21.8 0.1 0.00063 19.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GBG68993.1 - 0.00043 20.1 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 GBG68993.1 - 0.00051 20.3 0.4 0.0045 17.3 0.1 2.6 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 GBG68993.1 - 0.0011 19.2 0.1 0.003 17.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GBG68993.1 - 0.0011 19.0 0.0 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG68993.1 - 0.0019 18.6 0.1 0.024 15.0 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 GBG68993.1 - 0.004 16.4 0.3 0.0094 15.2 0.1 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 GBG68993.1 - 0.0041 16.5 0.1 0.011 15.1 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 GBG68993.1 - 0.0051 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GBG68993.1 - 0.017 15.6 0.0 0.065 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GBG68993.1 - 0.038 13.5 0.1 0.092 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GBG68993.1 - 0.051 14.0 0.0 0.18 12.2 0.0 2.1 1 1 0 1 1 1 0 RNA helicase Guanylate_kin PF00625.21 GBG68993.1 - 0.092 12.4 0.1 0.58 9.8 0.0 2.2 1 1 1 2 2 2 0 Guanylate kinase AAA_24 PF13479.6 GBG68993.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 GBG68993.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 GBG68993.1 - 0.14 11.7 1.1 0.74 9.4 0.4 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 GBG68993.1 - 0.15 12.0 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Plasmodium_Vir PF05795.11 GBG68993.1 - 6.4 6.1 5.1 21 4.4 5.1 1.8 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SUIM_assoc PF16619.5 GBG68994.1 - 0.044 13.9 5.3 0.13 12.3 5.3 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FAM220 PF15487.6 GBG68994.1 - 0.9 9.1 3.5 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 FAM220 family Spt20 PF12090.8 GBG68994.1 - 2.8 7.5 8.1 4.5 6.8 8.1 1.2 1 0 0 1 1 1 0 Spt20 family RT_RNaseH PF17917.1 GBG68997.1 - 1.1e-21 77.1 0.0 3.3e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG68997.1 - 2.7e-21 75.5 0.0 6.3e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68997.1 - 2.6e-17 62.7 0.8 6.2e-17 61.4 0.8 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68997.1 - 9.4e-16 58.1 0.0 2.7e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Topo_Zn_Ribbon PF08272.11 GBG68997.1 - 0.053 13.2 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-H2C2 PF09337.10 GBG68997.1 - 0.21 11.8 0.4 0.59 10.4 0.4 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG68999.1 - 6.6e-32 110.8 0.1 1.2e-31 110.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG68999.1 - 2.2e-31 107.8 0.2 6.2e-31 106.4 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG68999.1 - 1.3e-28 99.3 0.2 3.5e-28 98.0 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG68999.1 - 1.8e-19 69.6 0.1 4.2e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG68999.1 - 2e-15 57.0 0.0 4.8e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG68999.1 - 0.0028 17.8 0.0 0.0097 16.1 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG68999.1 - 0.044 13.5 1.8 0.079 12.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) Ribosomal_L31e PF01198.19 GBG69000.1 - 7.3e-42 141.5 4.0 9.1e-42 141.2 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e gag-asp_proteas PF13975.6 GBG69001.1 - 8.6e-05 23.0 0.7 0.00037 21.0 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69001.1 - 0.0012 19.4 0.2 0.0078 16.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RXLR PF16810.5 GBG69001.1 - 6.6 7.2 6.3 9 6.7 0.3 2.8 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Integrase_H2C2 PF17921.1 GBG69002.1 - 4.7e-13 49.0 0.0 1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69002.1 - 4.7e-06 26.8 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Str_synth PF03088.16 GBG69003.1 - 2.8e-30 104.3 0.0 7e-30 103.0 0.0 1.7 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 GBG69003.1 - 4.9e-14 52.5 0.0 3.4e-13 49.8 0.0 2.2 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GBG69003.1 - 6e-05 22.9 0.2 0.69 10.1 0.0 4.0 4 0 0 4 4 4 2 NHL repeat Arylesterase PF01731.20 GBG69003.1 - 0.0069 16.6 0.0 0.024 14.8 0.0 1.9 1 1 0 1 1 1 1 Arylesterase SBBP PF06739.11 GBG69003.1 - 0.07 13.1 0.7 0.81 9.7 0.0 2.7 3 0 0 3 3 3 0 Beta-propeller repeat TGF_beta_GS PF08515.12 GBG69003.1 - 0.19 11.3 0.9 6.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Pkinase PF00069.25 GBG69005.1 - 3.6e-21 75.7 0.0 5.4e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG69005.1 - 9.2e-06 25.1 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 GBG69005.1 - 0.0074 15.9 0.0 2.6 7.6 0.0 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Na_trans_assoc PF06512.13 GBG69006.1 - 0.035 14.4 9.7 0.053 13.8 9.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Afi1 PF07792.12 GBG69006.1 - 0.12 12.9 3.0 0.46 11.0 0.4 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FoP_duplication PF13865.6 GBG69006.1 - 0.39 11.3 39.9 1.8 9.1 21.6 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Presenilin PF01080.17 GBG69006.1 - 1.1 8.0 4.7 1.4 7.6 4.7 1.1 1 0 0 1 1 1 0 Presenilin PTPRCAP PF15713.5 GBG69006.1 - 1.5 9.1 25.9 2.3 8.5 1.8 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated NOA36 PF06524.12 GBG69006.1 - 1.6 8.0 17.9 1.9 7.7 7.8 2.1 2 0 0 2 2 2 0 NOA36 protein PBP1_TM PF14812.6 GBG69006.1 - 1.6 9.1 21.0 0.39 11.1 5.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CPSF100_C PF13299.6 GBG69006.1 - 2.5 8.2 7.8 4.1 7.5 2.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2052 PF09747.9 GBG69006.1 - 2.7 8.1 22.4 0.73 9.9 0.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DARPP-32 PF05395.12 GBG69006.1 - 6.7 6.9 19.9 8.5 6.6 0.4 2.1 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 TRAP_alpha PF03896.16 GBG69006.1 - 8.3 5.5 17.5 0.25 10.5 6.7 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Copine PF07002.16 GBG69007.1 - 4.8e-66 222.3 0.0 6.3e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 GBG69007.1 - 0.00088 19.4 0.0 0.0027 17.8 0.0 1.7 1 1 0 1 1 1 1 vWA found in TerF C terminus Keratin_2_head PF16208.5 GBG69007.1 - 1.7 8.7 46.6 21 5.2 0.1 2.2 2 0 0 2 2 2 0 Keratin type II head Ac76 PF05814.11 GBG69008.1 - 0.27 11.3 0.7 0.42 10.6 0.7 1.2 1 0 0 1 1 1 0 Orf76 (Ac76) PknG_TPR PF16918.5 GBG69009.1 - 0.086 11.6 0.1 0.15 10.8 0.1 1.4 1 1 0 1 1 1 0 Protein kinase G tetratricopeptide repeat HTH_Bact PF18768.1 GBG69010.1 - 0.081 12.5 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain U79_P34 PF03064.16 GBG69010.1 - 0.37 10.1 10.2 0.66 9.3 10.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.14 GBG69010.1 - 0.97 7.6 3.2 0.93 7.7 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4604 PF15377.6 GBG69010.1 - 2.7 8.4 15.4 5.6 7.4 15.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF3176 PF11374.8 GBG69011.1 - 0.13 12.5 0.4 0.75 10.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3176) DUF659 PF04937.15 GBG69013.1 - 1.4e-10 41.2 0.0 3.4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG69013.1 - 0.00015 21.4 0.1 0.0003 20.5 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Orf78 PF06024.12 GBG69013.1 - 0.12 12.7 2.6 7.6 6.9 0.6 2.5 2 0 0 2 2 2 0 Orf78 (ac78) 60KD_IMP PF02096.20 GBG69013.1 - 5.3 6.9 33.0 0.17 11.8 1.5 2.4 2 0 0 2 2 2 0 60Kd inner membrane protein EGF_CA PF07645.15 GBG69014.1 - 5.1e-12 45.8 61.0 8.3e-08 32.3 8.1 5.3 5 0 0 5 5 5 5 Calcium-binding EGF domain EGF PF00008.27 GBG69014.1 - 1.7e-08 34.6 74.8 0.013 15.8 12.4 6.1 6 0 0 6 6 6 5 EGF-like domain cEGF PF12662.7 GBG69014.1 - 5.7e-07 29.3 41.9 0.0043 16.9 3.7 5.8 5 1 0 5 5 5 5 Complement Clr-like EGF-like hEGF PF12661.7 GBG69014.1 - 2.6e-06 27.8 70.1 0.0073 16.9 6.3 6.6 6 1 0 6 6 6 4 Human growth factor-like EGF EGF_3 PF12947.7 GBG69014.1 - 1.3e-05 25.3 42.6 0.31 11.3 0.5 5.6 5 1 0 5 5 5 5 EGF domain FXa_inhibition PF14670.6 GBG69014.1 - 0.00045 20.4 58.9 1 9.7 3.0 5.5 4 1 1 5 5 5 5 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 GBG69014.1 - 0.14 12.6 66.5 1.2 9.6 4.8 5.9 6 0 0 6 6 6 0 EGF-like domain DDE_Tnp_4 PF13359.6 GBG69015.1 - 5.7e-15 55.3 0.0 1.2e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69015.1 - 8.6e-05 22.2 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein V_ATPase_I PF01496.19 GBG69015.1 - 0.31 8.9 1.7 0.42 8.5 1.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2362 PF10154.9 GBG69015.1 - 1.1 8.2 8.6 1.8 7.5 8.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Myb_DNA-bind_5 PF13873.6 GBG69016.1 - 0.0091 16.0 0.2 0.016 15.2 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Orexin PF02072.15 GBG69016.1 - 0.44 10.5 2.9 0.26 11.2 0.5 1.8 2 0 0 2 2 2 0 Prepro-orexin DDE_Tnp_4 PF13359.6 GBG69018.1 - 1.9e-27 95.9 0.0 3.8e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69018.1 - 1.2e-12 47.9 0.0 1.9e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG69018.1 - 0.028 14.8 0.7 0.16 12.3 0.0 2.5 3 0 0 3 3 3 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG69020.1 - 2.1e-07 31.2 4.1 2.1e-07 31.2 4.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG69020.1 - 0.0087 16.3 1.7 0.016 15.5 1.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Gln_amidase PF15644.6 GBG69020.1 - 0.037 15.0 1.5 7.1 7.7 0.1 2.5 2 1 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase Phage_min_tail PF05939.13 GBG69020.1 - 0.072 13.5 0.8 0.17 12.3 0.7 1.6 1 1 0 1 1 1 0 Phage minor tail protein PPP5 PF08321.12 GBG69021.1 - 1.5e-26 92.5 1.4 1.6e-19 70.0 0.0 3.1 3 0 0 3 3 3 2 PPP5 TPR repeat region Metallophos PF00149.28 GBG69021.1 - 1.1e-23 84.8 0.1 1.8e-09 38.4 0.1 3.2 2 1 1 3 3 3 3 Calcineurin-like phosphoesterase TPR_1 PF00515.28 GBG69021.1 - 3.1e-21 74.3 2.3 1.9e-09 36.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG69021.1 - 3.1e-16 58.1 3.0 4.3e-07 29.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG69021.1 - 1.8e-13 49.6 0.6 4.5e-05 23.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG69021.1 - 2.1e-12 46.5 1.9 0.00028 20.5 0.0 3.5 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 GBG69021.1 - 1.6e-08 35.1 1.2 0.00045 20.8 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG69021.1 - 1.1e-07 32.0 0.4 0.014 16.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG69021.1 - 1.7e-07 31.3 0.1 0.0058 16.8 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG69021.1 - 3.8e-07 30.0 0.4 0.06 13.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG69021.1 - 2.6e-06 27.6 1.5 0.0011 19.2 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG69021.1 - 3.8e-06 27.3 0.0 0.17 12.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG69021.1 - 2.7e-05 23.9 0.1 0.092 12.8 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG69021.1 - 2.8e-05 24.5 1.0 0.0057 17.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG69021.1 - 0.0043 16.9 2.6 0.29 11.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG69021.1 - 0.0098 16.1 2.4 2.3 8.5 0.9 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 GBG69021.1 - 0.066 12.7 0.0 7.6 6.1 0.0 2.9 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.18 GBG69021.1 - 0.076 13.1 1.7 1.2 9.2 0.4 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 GBG69021.1 - 0.11 12.6 0.6 22 5.2 0.1 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat PPP5 PF08321.12 GBG69022.1 - 1.8e-31 108.3 1.2 5.3e-31 106.8 0.2 2.2 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 GBG69022.1 - 1.6e-21 75.1 2.3 1.5e-09 37.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG69022.1 - 1.5e-16 59.1 3.0 3.4e-07 29.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat Metallophos PF00149.28 GBG69022.1 - 4.4e-14 53.5 0.1 1.4e-09 38.8 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase TPR_8 PF13181.6 GBG69022.1 - 8.6e-14 50.5 0.6 3.5e-05 23.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG69022.1 - 1.3e-12 47.2 2.1 0.00022 20.8 0.0 3.5 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 GBG69022.1 - 9.4e-09 35.8 1.2 0.00034 21.2 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG69022.1 - 6.7e-08 32.7 0.4 0.011 16.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG69022.1 - 1e-07 32.0 0.1 0.0045 17.1 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG69022.1 - 2.2e-07 30.8 0.4 0.047 14.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG69022.1 - 1.6e-06 28.3 1.6 0.00089 19.5 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG69022.1 - 2e-06 28.2 0.0 0.13 12.8 0.0 3.0 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG69022.1 - 1.7e-05 25.1 1.0 0.0045 17.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG69022.1 - 1.9e-05 24.4 0.3 0.072 13.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG69022.1 - 0.0026 17.6 2.6 0.23 11.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG69022.1 - 0.0058 16.8 2.4 1.8 8.9 0.9 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 GBG69022.1 - 0.039 13.4 0.0 6.1 6.4 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.18 GBG69022.1 - 0.046 13.8 1.9 1.1 9.4 0.5 3.1 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 GBG69022.1 - 0.17 12.0 2.0 18 5.5 0.1 2.8 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 GBG69023.1 - 9.3e-22 75.9 2.3 1.3e-09 37.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG69023.1 - 9.7e-17 59.7 3.0 2.9e-07 30.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat Metallophos PF00149.28 GBG69023.1 - 1.6e-15 58.2 0.0 2.5e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_8 PF13181.6 GBG69023.1 - 5.9e-14 51.0 0.6 3e-05 23.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG69023.1 - 7.4e-13 48.0 2.0 0.00019 21.0 0.0 3.5 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 GBG69023.1 - 7.4e-09 36.1 1.2 0.00029 21.4 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG69023.1 - 5.5e-08 33.0 0.4 0.0094 16.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG69023.1 - 7.7e-08 32.4 0.1 0.0038 17.3 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG69023.1 - 1.5e-07 31.3 0.4 0.041 14.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG69023.1 - 1.1e-06 28.9 1.6 0.00075 19.7 0.2 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG69023.1 - 6e-06 26.7 0.1 0.11 13.0 0.0 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG69023.1 - 1.3e-05 24.9 0.3 0.063 13.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG69023.1 - 1.4e-05 25.5 1.0 0.0039 17.7 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat PPP5 PF08321.12 GBG69023.1 - 6.5e-05 23.1 0.4 0.00038 20.7 0.1 2.3 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_10 PF13374.6 GBG69023.1 - 0.0014 18.5 2.6 0.2 11.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG69023.1 - 0.0053 16.9 2.4 1.5 9.1 0.9 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 GBG69023.1 - 0.028 13.9 0.1 5.4 6.6 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.18 GBG69023.1 - 0.036 14.1 1.9 0.92 9.6 0.5 3.0 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 GBG69023.1 - 0.096 12.8 1.6 15 5.7 0.1 2.7 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat Spt20 PF12090.8 GBG69024.1 - 0.0051 16.4 6.8 0.0069 16.0 6.8 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 GBG69024.1 - 0.045 12.7 5.6 0.057 12.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 GBG69024.1 - 0.11 12.5 8.1 0.16 11.9 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 GBG69024.1 - 0.25 11.4 14.1 0.69 10.0 14.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Androgen_recep PF02166.16 GBG69024.1 - 0.78 8.5 11.7 1.9 7.3 11.7 1.6 1 0 0 1 1 1 0 Androgen receptor TRM PF02005.16 GBG69025.1 - 1.2e-119 399.8 0.0 1.6e-119 399.5 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 GBG69025.1 - 0.00014 22.5 0.0 0.00065 20.4 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GBG69025.1 - 0.0002 20.9 0.1 0.0003 20.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 GBG69025.1 - 0.0002 21.0 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 GBG69025.1 - 0.00046 20.0 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG69025.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 GBG69025.1 - 0.17 11.6 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Zn_ribbon_SprT PF17283.2 GBG69025.1 - 2.2 8.3 5.6 0.36 10.8 0.5 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF4419 PF14388.6 GBG69028.1 - 1.9e-28 99.7 0.0 6.3e-20 71.8 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4419) gag-asp_proteas PF13975.6 GBG69029.1 - 2.9e-07 31.0 0.2 1e-06 29.2 0.1 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69029.1 - 9.9e-06 26.1 0.3 4e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG69029.1 - 0.00087 19.1 0.1 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69029.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG69029.1 - 0.023 14.4 0.2 0.056 13.1 0.2 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Hex_IIIa PF02455.16 GBG69029.1 - 0.25 10.1 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) zf-CCHC PF00098.23 GBG69029.1 - 0.46 10.7 2.0 0.82 9.9 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle THF_DHG_CYH_C PF02882.19 GBG69030.1 - 6.7e-66 220.5 0.2 1.2e-65 219.7 0.2 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GBG69030.1 - 5.6e-35 120.1 0.2 1.3e-34 119.0 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain RT_RNaseH_2 PF17919.1 GBG69030.1 - 5.6e-28 96.9 0.0 1e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69030.1 - 5.9e-27 94.0 0.0 1.1e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69030.1 - 4.6e-17 62.3 0.1 7.4e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AlaDh_PNT_C PF01262.21 GBG69030.1 - 0.035 13.4 0.0 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Nop14 PF04147.12 GBG69030.1 - 0.98 7.6 10.6 1.3 7.1 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG69030.1 - 1.3 8.8 5.8 2.2 8.1 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 GBG69030.1 - 1.4 8.2 10.8 2.5 7.5 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DEAD PF00270.29 GBG69032.1 - 1e-45 155.7 0.0 2.9e-45 154.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG69032.1 - 6.3e-31 107.0 0.0 2.4e-30 105.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG69032.1 - 9.8e-05 22.4 0.0 0.00037 20.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 GBG69032.1 - 0.0033 17.4 2.5 0.0033 17.4 2.5 1.9 2 0 0 2 2 2 1 Zinc knuckle SecA_DEAD PF07517.14 GBG69032.1 - 0.0079 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain zf-CCHC_4 PF14392.6 GBG69032.1 - 0.32 10.8 1.7 0.99 9.2 0.5 2.2 2 0 0 2 2 2 0 Zinc knuckle CMS1 PF14617.6 GBG69032.1 - 6.1 6.1 5.8 0.6 9.4 0.1 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ribonuc_L-PSP PF01042.21 GBG69033.1 - 4.6e-17 62.2 0.0 9.4e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP RVT_1 PF00078.27 GBG69034.1 - 2.8e-09 36.8 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4490 PF14892.6 GBG69035.1 - 4.4e-12 46.0 0.2 4.4e-12 46.0 0.2 3.5 2 1 2 4 4 4 1 Domain of unknown function (DUF4490) SDA1 PF05285.12 GBG69035.1 - 1.2e-05 24.9 30.6 1.2e-05 24.9 30.6 2.1 2 0 0 2 2 2 1 SDA1 NTP_transf_3 PF12804.7 GBG69035.1 - 0.0021 18.4 0.0 0.45 10.8 0.0 2.3 2 0 0 2 2 2 2 MobA-like NTP transferase domain Hid1 PF12722.7 GBG69035.1 - 1.7 6.6 19.7 2.7 6.0 19.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RVT_1 PF00078.27 GBG69036.1 - 1.2e-24 87.0 0.1 2e-24 86.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69036.1 - 4.5e-12 46.2 0.0 1.5e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG69036.1 - 5.6e-12 45.4 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG69036.1 - 0.034 14.2 9.5 0.47 10.6 2.8 3.7 4 1 0 4 4 4 0 Integrase zinc binding domain GIY-YIG PF01541.24 GBG69037.1 - 5.8e-07 29.7 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain RVT_1 PF00078.27 GBG69038.1 - 6.6e-21 74.8 0.0 1.2e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NCBP3 PF10309.9 GBG69038.1 - 4.3e-19 68.1 0.0 1e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RVP_2 PF08284.11 GBG69038.1 - 0.0093 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RNA_bind PF08675.11 GBG69038.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain Het-C PF07217.11 GBG69038.1 - 2.2 6.7 5.4 3.9 5.9 5.4 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C VPS38 PF17649.1 GBG69038.1 - 4.7 6.0 9.8 8.9 5.1 9.8 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DDE_Tnp_4 PF13359.6 GBG69039.1 - 3.4e-12 46.3 0.0 5.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69039.1 - 5.7e-06 26.1 0.0 2e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG69039.1 - 0.16 11.6 0.2 3.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG69040.1 - 8.3e-05 22.9 0.3 0.00016 22.0 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Herpes_ICP4_N PF03584.15 GBG69040.1 - 0.56 10.0 2.3 6.1 6.6 2.3 2.2 1 1 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region DUF4680 PF15730.5 GBG69041.1 - 2.5 8.4 7.1 3.1 8.2 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) NOA36 PF06524.12 GBG69043.1 - 0.39 10.0 5.2 0.61 9.3 5.2 1.3 1 0 0 1 1 1 0 NOA36 protein Lipase_GDSL_2 PF13472.6 GBG69044.1 - 6.4e-21 75.5 0.0 1.5e-20 74.3 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GBG69044.1 - 1.2e-17 64.5 0.0 1.8e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AF-4 PF05110.13 GBG69045.1 - 0.001 17.3 5.4 0.001 17.3 5.4 2.8 2 1 0 2 2 2 1 AF-4 proto-oncoprotein PPP4R2 PF09184.11 GBG69045.1 - 9.5 5.7 22.7 23 4.5 22.7 1.8 1 1 0 1 1 1 0 PPP4R2 DUF1564 PF07600.11 GBG69046.1 - 0.011 15.4 0.0 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DNA_pol_phi PF04931.13 GBG69046.1 - 0.099 10.7 22.0 0.19 9.8 22.0 1.5 1 0 0 1 1 1 0 DNA polymerase phi DUF2796 PF10986.8 GBG69046.1 - 0.27 11.2 20.0 7.2 6.6 16.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) DUF2151 PF10221.9 GBG69046.1 - 0.53 8.8 10.3 0.69 8.4 10.3 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Nop14 PF04147.12 GBG69046.1 - 1.1 7.3 29.3 1.6 6.9 29.3 1.2 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.11 GBG69046.1 - 5.7 6.5 31.6 1.8 8.2 28.9 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CDC27 PF09507.10 GBG69046.1 - 8 5.7 39.9 0.55 9.6 35.1 1.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 RT_RNaseH_2 PF17919.1 GBG69047.1 - 3.9e-21 74.9 0.1 7.4e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69047.1 - 2.2e-09 37.6 0.0 5.4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_C78 PF07910.13 GBG69048.1 - 1.2e-54 185.0 2.0 2.2e-39 135.1 0.1 3.2 3 0 0 3 3 3 2 Peptidase family C78 RT_RNaseH PF17917.1 GBG69048.1 - 3.8e-31 107.5 0.9 1e-30 106.1 0.1 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69048.1 - 9.1e-31 105.9 0.0 5.6e-30 103.3 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69048.1 - 7.6e-26 91.0 0.1 2.3e-25 89.4 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG69048.1 - 9.9e-19 67.2 0.8 3.2e-18 65.6 0.8 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69048.1 - 7.4e-15 55.2 0.0 3.8e-14 52.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain ZZ PF00569.17 GBG69048.1 - 3.9e-06 26.6 0.1 1.1e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-H2C2 PF09337.10 GBG69048.1 - 0.01 16.1 1.2 0.017 15.4 0.1 2.0 2 0 0 2 2 2 0 H2C2 zinc finger Peptidase_C54 PF03416.19 GBG69048.1 - 0.082 12.3 0.8 0.21 11.0 0.1 1.9 2 0 0 2 2 2 0 Peptidase family C54 Phage_GPO PF05929.11 GBG69048.1 - 2.9 7.5 22.4 0.23 11.1 0.1 3.4 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3769 PF12600.8 GBG69050.1 - 1.9e-12 46.9 0.0 1.8e-05 23.8 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3769) DUF773 PF05600.12 GBG69051.1 - 9.6e-137 456.8 0.1 1.9e-136 455.8 0.1 1.4 1 1 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 DUF2452 PF10504.9 GBG69051.1 - 0.033 13.7 0.1 0.069 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) DHR10 PF18595.1 GBG69051.1 - 6.4 6.9 10.5 1.1 9.4 0.8 3.4 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain RVT_1 PF00078.27 GBG69053.1 - 8.4e-30 103.9 0.0 1.3e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69053.1 - 4e-25 87.8 0.0 1e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69053.1 - 1.8e-23 82.8 0.0 4.2e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69053.1 - 8.4e-17 61.0 0.3 1.9e-16 59.9 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69053.1 - 6.6e-09 36.0 0.0 2.2e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG69053.1 - 0.0024 18.5 0.0 0.0056 17.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69053.1 - 0.0029 18.1 0.0 0.0061 17.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG69053.1 - 0.0074 16.1 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG69053.1 - 0.025 14.8 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG69053.1 - 0.028 14.2 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Chromo PF00385.24 GBG69053.1 - 0.19 11.6 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain WD40 PF00400.32 GBG69054.1 - 6.1e-07 30.1 11.0 0.033 15.0 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.11 GBG69054.1 - 0.00024 21.0 0.0 0.0081 16.1 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 GBG69054.1 - 0.00069 19.9 0.0 0.052 13.8 0.0 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GBG69054.1 - 0.032 14.2 0.3 2.9 8.0 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF2282 PF10048.9 GBG69055.1 - 0.069 13.2 0.7 8 6.6 0.1 2.3 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2282) PH PF00169.29 GBG69057.1 - 3.6e-22 78.9 0.6 4.4e-22 78.6 0.6 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GBG69057.1 - 4.5e-09 36.7 2.0 8.6e-09 35.8 2.0 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 GBG69057.1 - 3.5e-05 24.1 0.1 7.9e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GBG69057.1 - 0.0018 18.5 0.1 0.0027 17.9 0.1 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 GBG69057.1 - 0.0096 16.3 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH_3 PF14593.6 GBG69057.1 - 0.013 15.6 0.1 0.019 15.1 0.1 1.3 1 0 0 1 1 1 0 PH domain PH_6 PF15406.6 GBG69057.1 - 0.071 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain zf-CCHC PF00098.23 GBG69058.1 - 6.4e-05 22.8 1.2 0.0001 22.2 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Ldh_1_C PF02866.18 GBG69059.1 - 1.4e-36 125.9 0.0 2.2e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GBG69059.1 - 3.6e-30 104.9 0.3 5.8e-30 104.2 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Pkip-1 PF06878.11 GBG69060.1 - 0.029 14.5 4.1 0.06 13.4 4.1 1.5 1 0 0 1 1 1 0 Pkip-1 protein Ldh_1_C PF02866.18 GBG69062.1 - 1e-38 132.9 0.1 1.9e-38 132.1 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GBG69062.1 - 4.5e-31 107.8 0.3 8.6e-31 106.9 0.3 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain RCDG1 PF15725.5 GBG69062.1 - 0.046 14.1 0.2 0.26 11.7 0.0 2.1 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein PTSIIB_sorb PF03830.15 GBG69062.1 - 0.055 13.7 0.3 0.48 10.6 0.0 2.2 2 0 0 2 2 2 0 PTS system sorbose subfamily IIB component Polysacc_deac_2 PF04748.13 GBG69062.1 - 0.083 12.1 0.2 0.27 10.4 0.0 1.9 2 1 0 2 2 2 0 Divergent polysaccharide deacetylase GlcNAc-1_reg PF18440.1 GBG69062.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain OGG_N PF07934.12 GBG69063.1 - 1.3e-20 73.7 0.0 1.3e-20 73.7 0.0 2.4 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain PPP4R2 PF09184.11 GBG69063.1 - 0.2 11.2 35.5 0.95 9.0 25.1 2.2 2 0 0 2 2 2 0 PPP4R2 AAA_11 PF13086.6 GBG69063.1 - 1.1 8.9 28.9 2.4 7.9 28.9 1.6 1 0 0 1 1 1 0 AAA domain PA26 PF04636.13 GBG69063.1 - 6.8 5.5 17.6 11 4.7 17.6 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SepSecS PF05889.13 GBG69064.1 - 6.3e-120 400.4 0.0 7.6e-110 367.3 0.0 2.2 2 0 0 2 2 2 2 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 GBG69064.1 - 3.8e-05 23.1 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 GBG69064.1 - 0.00055 18.8 0.1 0.0013 17.6 0.1 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Myb_DNA-bind_2 PF08914.11 GBG69065.1 - 9.1e-11 41.8 0.0 4.6e-10 39.5 0.0 2.3 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 GBG69065.1 - 5.3e-07 30.0 0.0 1.5e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain GRP PF07172.11 GBG69065.1 - 0.0073 17.0 0.6 0.0073 17.0 0.6 4.0 4 1 0 4 4 2 1 Glycine rich protein family DUF228 PF02989.14 GBG69065.1 - 0.49 10.2 0.0 0.49 10.2 0.0 2.8 2 1 0 2 2 1 0 Lyme disease proteins of unknown function Lin-8 PF03353.15 GBG69065.1 - 0.8 9.2 28.1 2 7.9 28.1 1.7 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mem_trans PF03547.18 GBG69065.1 - 1 7.7 2.2 1.2 7.5 2.2 1.2 1 0 0 1 1 1 0 Membrane transport protein PAT1 PF09770.9 GBG69065.1 - 1.3 7.2 42.0 2.1 6.5 42.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 GBG69065.1 - 2.3 6.6 22.0 3.5 6.0 22.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 GBG69065.1 - 5 4.1 29.9 7 3.6 29.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 GBG69065.1 - 8.9 5.0 22.1 17 4.1 22.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter CRT10 PF08728.10 GBG69065.1 - 9.9 4.2 14.5 14 3.7 14.5 1.1 1 0 0 1 1 1 0 CRT10 zf-C2H2_2 PF12756.7 GBG69066.1 - 3.7e-11 43.2 0.0 7.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_25 PF13649.6 GBG69066.1 - 2.4e-10 41.0 0.3 9.5e-08 32.6 0.1 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG69066.1 - 7.1e-10 39.4 0.1 7.7e-08 32.9 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG69066.1 - 2.8e-07 30.5 0.0 1.3e-06 28.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GBG69066.1 - 3.4e-07 29.9 0.5 6e-07 29.1 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GBG69066.1 - 3.5e-05 23.6 0.2 0.00015 21.5 0.3 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG69066.1 - 0.00027 21.6 0.0 0.00085 20.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG69066.1 - 0.00059 19.4 0.2 0.0013 18.3 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase small domain BUD22 PF09073.10 GBG69066.1 - 0.013 14.9 13.2 0.016 14.6 8.4 2.5 2 1 0 2 2 2 0 BUD22 Methyltransf_32 PF13679.6 GBG69066.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 GBG69066.1 - 0.09 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 GBG69066.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-C2H2_4 PF13894.6 GBG69066.1 - 0.13 13.2 3.9 0.18 12.7 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltransf_18 PF12847.7 GBG69066.1 - 0.18 11.8 0.0 0.5 10.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain zf_C2H2_6 PF18450.1 GBG69066.1 - 4.3 7.1 5.3 18 5.2 1.2 2.5 2 0 0 2 2 2 0 Zinc Finger domain WzyE PF06899.11 GBG69067.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 WzyE protein, O-antigen assembly polymerase CENP-B_dimeris PF09026.10 GBG69067.1 - 2.1 8.8 9.9 6.1 7.3 9.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 GBG69067.1 - 3.7 5.6 10.7 5.9 5.0 10.7 1.2 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 GBG69067.1 - 6.2 5.9 6.0 11 5.1 6.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDE_Tnp_4 PF13359.6 GBG69070.1 - 4.1e-29 101.3 0.0 8.3e-29 100.3 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69070.1 - 3.3e-16 59.5 0.0 4.8e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG69070.1 - 6.1e-05 22.8 0.0 0.29 10.8 0.1 2.3 2 0 0 2 2 2 2 Transposase DDE domain adh_short PF00106.25 GBG69074.1 - 3.3e-47 160.5 0.1 4.3e-47 160.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG69074.1 - 6.9e-35 120.7 0.1 8.2e-35 120.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG69074.1 - 2.9e-09 37.1 0.1 4.4e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 GBG69074.1 - 0.028 14.4 1.5 0.19 11.7 1.5 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 GBG69074.1 - 0.033 13.4 0.7 0.062 12.5 0.6 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG69074.1 - 0.036 14.6 0.2 0.089 13.4 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 GBG69074.1 - 0.064 12.4 0.1 0.075 12.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 GBG69074.1 - 0.076 12.5 0.5 0.14 11.6 0.5 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1769 PF08588.10 GBG69074.1 - 0.4 10.9 0.1 0.4 10.9 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1769) DUF842 PF05811.13 GBG69075.1 - 5e-36 123.3 14.4 5.7e-36 123.1 14.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) BTG PF07742.12 GBG69075.1 - 0.038 13.8 1.3 0.18 11.7 0.4 2.0 1 1 1 2 2 2 0 BTG family ZipA_C PF04354.13 GBG69075.1 - 0.15 11.9 0.1 2.2 8.2 0.1 2.1 2 0 0 2 2 2 0 ZipA, C-terminal FtsZ-binding domain zf-Tim10_DDP PF02953.15 GBG69075.1 - 1.3 8.7 16.6 0.33 10.6 1.9 2.6 1 1 1 2 2 2 0 Tim10/DDP family zinc finger Vicilin_N PF04702.12 GBG69075.1 - 8.2 6.3 22.4 7.1 6.4 5.3 2.2 1 1 1 2 2 2 0 Vicilin N terminal region zf-CCHC PF00098.23 GBG69076.1 - 7.9e-09 35.2 1.2 2.5e-08 33.6 1.2 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG69076.1 - 0.011 15.5 2.7 0.027 14.3 2.7 1.7 1 0 0 1 1 1 0 Zinc knuckle NAD_binding_10 PF13460.6 GBG69077.1 - 5e-14 52.6 0.4 1e-12 48.3 0.4 2.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GBG69077.1 - 8.3e-07 28.8 0.1 1.7e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 GBG69077.1 - 9.2e-07 28.6 0.9 1.3e-06 28.0 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GBG69077.1 - 3.4e-05 23.0 0.0 0.00053 19.1 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GBG69077.1 - 0.00021 20.5 0.2 0.13 11.3 0.0 2.8 3 0 0 3 3 3 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GBG69077.1 - 0.047 13.1 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GBG69077.1 - 0.15 11.2 0.0 5.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein F420_oxidored PF03807.17 GBG69077.1 - 0.19 12.3 1.2 2.6 8.7 0.2 2.6 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent FF PF01846.19 GBG69078.1 - 1.5e-41 140.3 26.5 1.8e-13 50.4 0.4 5.9 5 1 0 5 5 5 5 FF domain WW PF00397.26 GBG69078.1 - 3.8e-14 52.5 7.7 5.8e-08 32.7 0.6 2.6 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 GBG69078.1 - 0.018 15.3 3.1 2.4 8.5 0.2 2.6 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain RhoGAP-FF1 PF16512.5 GBG69078.1 - 0.69 10.6 8.1 2.6 8.8 0.1 3.9 4 0 0 4 4 4 0 p190-A and -B Rho GAPs FF domain WW PF00397.26 GBG69079.1 - 2e-08 34.2 0.6 3.8e-08 33.3 0.6 1.5 1 0 0 1 1 1 1 WW domain DNA_pol3_beta PF00712.19 GBG69081.1 - 7.1e-14 52.0 0.0 1.1e-12 48.2 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_3 PF02768.15 GBG69081.1 - 4.6e-09 36.2 0.0 1.3e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase III beta subunit, C-terminal domain Rhodanese PF00581.20 GBG69082.1 - 4.5e-08 33.6 0.0 1.1e-07 32.4 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain zf-RING_7 PF02591.15 GBG69082.1 - 0.13 12.4 0.7 0.57 10.4 0.3 2.1 2 0 0 2 2 2 0 C4-type zinc ribbon domain RT_RNaseH PF17917.1 GBG69083.1 - 3.1e-22 78.8 0.0 8.7e-22 77.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69083.1 - 1.6e-20 73.0 0.0 7.7e-20 70.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG69083.1 - 0.00038 21.0 0.0 0.001 19.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69083.1 - 0.0015 19.1 0.0 0.0041 17.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease IFRD PF05004.13 GBG69084.1 - 2.6e-71 240.3 0.0 7.5e-71 238.7 0.0 1.8 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 GBG69084.1 - 3.9e-08 33.8 0.1 1.2e-07 32.2 0.1 1.9 1 0 0 1 1 1 1 Interferon-related protein conserved region HEAT_2 PF13646.6 GBG69084.1 - 0.016 15.5 0.4 2.3 8.7 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 GBG69084.1 - 0.039 14.2 1.4 5.5 7.5 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 GBG69084.1 - 0.13 12.8 7.3 3.1 8.4 0.5 3.3 3 0 0 3 3 3 0 HEAT-like repeat Pribosyltran_N PF13793.6 GBG69085.1 - 4.2e-49 165.3 0.0 6.9e-49 164.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GBG69085.1 - 1.8e-25 90.1 0.1 8.5e-25 87.9 0.0 2.0 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GBG69085.1 - 2.1e-17 63.1 0.4 4.3e-17 62.1 0.2 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GBG69085.1 - 0.021 14.3 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TMEM154 PF15102.6 GBG69086.1 - 2.3 8.1 3.5 0.97 9.3 0.5 1.9 2 0 0 2 2 2 0 TMEM154 protein family Helicase_C PF00271.31 GBG69087.1 - 1.1e-23 83.7 0.0 3.2e-23 82.2 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GBG69087.1 - 0.0054 15.9 0.0 0.017 14.3 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 GBG69087.1 - 0.035 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2703 PF10865.8 GBG69087.1 - 0.052 13.7 0.1 0.092 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) DprA_WH PF17782.1 GBG69087.1 - 0.14 12.3 0.3 0.38 10.9 0.3 1.7 1 0 0 1 1 1 0 DprA winged helix domain FF PF01846.19 GBG69088.1 - 1.7e-51 172.2 19.8 1.7e-13 50.5 3.6 5.7 5 0 0 5 5 5 5 FF domain SNF2_N PF00176.23 GBG69088.1 - 8.3e-33 113.5 1.3 8.3e-33 113.5 1.3 2.8 3 0 0 3 3 3 1 SNF2 family N-terminal domain WW PF00397.26 GBG69088.1 - 5.6e-15 55.1 14.2 2.4e-09 37.1 3.6 2.5 2 0 0 2 2 2 2 WW domain eIF3_subunit PF08597.10 GBG69088.1 - 0.00072 19.5 8.4 0.00072 19.5 8.4 8.9 6 2 3 9 9 9 1 Translation initiation factor eIF3 subunit DDHD PF02862.17 GBG69088.1 - 0.0039 17.4 6.9 0.0039 17.4 6.9 7.8 5 3 0 5 5 5 1 DDHD domain RPAP3_C PF13877.6 GBG69089.1 - 4.3e-22 78.5 0.0 1e-21 77.3 0.0 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 GBG69089.1 - 1.8e-21 75.0 3.2 1.1e-06 28.2 1.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG69089.1 - 5.8e-17 60.4 2.7 0.00016 21.5 0.9 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG69089.1 - 1.1e-09 37.7 1.3 0.0025 17.9 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG69089.1 - 3.5e-09 36.2 0.2 4e-05 23.2 0.0 3.3 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 GBG69089.1 - 9.1e-08 32.6 2.2 3.4e-06 27.6 0.0 3.3 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG69089.1 - 5.9e-06 26.5 7.5 0.00053 20.2 0.3 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 GBG69089.1 - 0.0018 18.1 3.1 0.079 12.9 0.4 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG69089.1 - 0.0026 17.7 1.9 0.67 10.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GBG69089.1 - 0.01 16.0 1.1 1.4 9.2 0.5 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Adeno_VII PF03228.14 GBG69089.1 - 0.02 15.5 0.3 0.082 13.5 0.3 2.1 1 0 0 1 1 1 0 Adenoviral core protein VII Fis1_TPR_C PF14853.6 GBG69089.1 - 0.079 13.0 0.5 4.4 7.4 0.1 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 GBG69089.1 - 0.95 10.5 9.3 2.1 9.4 0.0 4.4 2 2 2 4 4 3 0 Tetratricopeptide repeat DUF2457 PF10446.9 GBG69090.1 - 0.00028 20.2 21.7 0.00032 20.0 21.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) FYDLN_acid PF09538.10 GBG69090.1 - 0.0051 17.5 17.0 0.0074 17.0 17.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) Cwf_Cwc_15 PF04889.12 GBG69090.1 - 0.0082 15.9 16.2 0.0093 15.7 16.2 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG69090.1 - 0.022 13.0 14.3 0.021 13.0 14.3 1.0 1 0 0 1 1 1 0 Nop14-like family Connexin PF00029.19 GBG69090.1 - 0.032 14.0 0.4 0.041 13.7 0.4 1.1 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 GBG69090.1 - 0.037 14.2 2.2 0.036 14.3 2.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PPP4R2 PF09184.11 GBG69090.1 - 0.044 13.4 12.5 0.049 13.2 12.5 1.1 1 0 0 1 1 1 0 PPP4R2 CDC27 PF09507.10 GBG69090.1 - 0.056 12.8 7.8 0.059 12.8 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Retinal PF15449.6 GBG69090.1 - 0.068 11.0 3.1 0.075 10.8 3.1 1.0 1 0 0 1 1 1 0 Retinal protein BUD22 PF09073.10 GBG69090.1 - 0.099 12.0 13.0 0.1 12.0 13.0 1.1 1 0 0 1 1 1 0 BUD22 GRP PF07172.11 GBG69090.1 - 0.1 13.3 0.4 0.14 12.8 0.4 1.2 1 0 0 1 1 1 0 Glycine rich protein family Sigma70_ner PF04546.13 GBG69090.1 - 0.11 12.4 10.1 0.13 12.2 10.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.12 GBG69090.1 - 0.11 11.8 15.4 0.15 11.4 15.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Afi1 PF07792.12 GBG69090.1 - 0.22 12.0 9.5 0.33 11.4 9.5 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4820 PF16091.5 GBG69090.1 - 0.32 10.3 4.4 0.34 10.2 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) OAD_gamma PF04277.13 GBG69090.1 - 0.34 11.5 0.6 0.51 11.0 0.6 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RNA_pol_3_Rpc31 PF11705.8 GBG69090.1 - 0.35 11.1 20.8 0.47 10.7 20.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Paf1 PF03985.13 GBG69090.1 - 0.41 9.6 12.6 0.5 9.3 12.6 1.1 1 0 0 1 1 1 0 Paf1 TFIIF_alpha PF05793.12 GBG69090.1 - 0.42 9.2 22.1 0.56 8.7 22.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NPR3 PF03666.13 GBG69090.1 - 0.45 9.3 3.8 0.47 9.2 3.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 GBG69090.1 - 0.46 9.9 15.9 0.49 9.8 15.9 1.1 1 0 0 1 1 1 0 SDA1 Mak16 PF04874.14 GBG69090.1 - 0.46 11.1 17.6 0.66 10.6 17.6 1.2 1 0 0 1 1 1 0 Mak16 protein C-terminal region TFB6 PF17110.5 GBG69090.1 - 0.47 10.2 10.9 0.65 9.7 10.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2076 PF09849.9 GBG69090.1 - 0.68 9.9 8.8 0.69 9.9 8.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SspB PF04386.13 GBG69090.1 - 0.78 9.6 6.0 1.1 9.2 6.0 1.2 1 0 0 1 1 1 0 Stringent starvation protein B Drc1-Sld2 PF11719.8 GBG69090.1 - 0.79 9.2 12.1 0.82 9.1 12.1 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nucleo_P87 PF07267.11 GBG69090.1 - 0.86 8.4 9.3 0.94 8.2 9.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol_phi PF04931.13 GBG69090.1 - 0.95 7.5 28.9 1.1 7.2 28.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Slu7 PF11708.8 GBG69090.1 - 1 9.0 14.3 1.5 8.6 14.3 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor YqfQ PF14181.6 GBG69090.1 - 1.2 9.3 3.1 1.5 9.0 3.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein Presenilin PF01080.17 GBG69090.1 - 2.6 6.7 3.3 2.7 6.7 3.3 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG69090.1 - 2.9 6.1 13.9 3.3 5.9 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 GBG69090.1 - 3.2 7.7 18.0 3.1 7.7 18.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HSP90 PF00183.18 GBG69090.1 - 5.7 5.7 11.8 6.2 5.6 11.8 1.0 1 0 0 1 1 1 0 Hsp90 protein PPL5 PF18168.1 GBG69090.1 - 6.5 6.0 6.6 7.8 5.7 6.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 TRAP_alpha PF03896.16 GBG69090.1 - 8.1 5.6 12.9 10 5.2 12.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Histone PF00125.24 GBG69091.1 - 5.3e-21 75.4 0.0 1.2e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_C48 PF02902.19 GBG69092.1 - 1.1e-14 54.8 1.1 2.4e-14 53.7 1.1 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1896 PF08989.10 GBG69092.1 - 0.0025 17.9 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1896) Glyco_transf_29 PF00777.18 GBG69093.1 - 0.034 13.5 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) PAP_fibrillin PF04755.12 GBG69094.1 - 6.4e-17 62.1 0.1 1.3e-11 44.8 0.0 2.2 1 1 1 2 2 2 2 PAP_fibrillin Cwf_Cwc_15 PF04889.12 GBG69095.1 - 0.21 11.3 3.1 0.31 10.7 3.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RT_RNaseH PF17917.1 GBG69096.1 - 2.5e-17 63.1 0.0 5.7e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69096.1 - 1.1e-10 41.4 0.0 2.2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PTPRCAP PF15713.5 GBG69096.1 - 0.54 10.5 12.0 1.6 9.0 12.0 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG69096.1 - 1.4 7.1 9.9 2 6.6 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG69096.1 - 1.8 7.9 11.0 3.1 7.1 11.0 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG69096.1 - 2.1 6.4 10.0 2.9 6.0 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3598 PF12204.8 GBG69097.1 - 0.0082 15.7 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3598) LCE6A PF15858.5 GBG69097.1 - 0.66 10.8 5.3 17 6.3 0.6 2.8 2 0 0 2 2 2 0 Late cornified envelope protein 6A family DUF2052 PF09747.9 GBG69098.1 - 0.011 15.9 1.4 0.011 15.9 1.4 1.8 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SKA1 PF07160.12 GBG69098.1 - 0.1 12.4 0.3 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DEK_C PF08766.11 GBG69100.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain PfkB PF00294.24 GBG69101.1 - 4.9e-25 88.4 0.0 7.5e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PfkB PF00294.24 GBG69102.1 - 6.4e-80 268.7 0.0 7.3e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Plavaka PF18759.1 GBG69103.1 - 6.4e-28 97.9 0.1 1e-27 97.2 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase CDC45 PF02724.14 GBG69103.1 - 4.1 5.6 11.1 7.3 4.8 11.1 1.3 1 0 0 1 1 1 0 CDC45-like protein SPX PF03105.19 GBG69103.1 - 8.1 6.2 17.0 2.5 8.0 13.9 1.6 2 0 0 2 2 2 0 SPX domain PfkB PF00294.24 GBG69104.1 - 2.7e-79 266.6 0.0 3.1e-79 266.4 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PK PF00224.21 GBG69105.1 - 1.3e-88 297.3 0.1 2e-88 296.6 0.1 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG69105.1 - 5.6e-23 81.4 0.0 1.3e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain DnaB_C PF03796.15 GBG69105.1 - 0.073 12.4 0.6 0.13 11.6 0.6 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mito_fiss_reg PF05308.11 GBG69105.1 - 1.3 9.1 7.9 4.5 7.3 7.9 1.9 1 0 0 1 1 1 0 Mitochondrial fission regulator VIR_N PF15912.5 GBG69105.1 - 2 8.0 3.9 4.2 6.9 3.9 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Pkinase PF00069.25 GBG69107.1 - 3.3e-37 128.3 0.0 6.1e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG69107.1 - 8e-37 126.9 0.0 2e-36 125.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG69107.1 - 7.7e-06 26.0 0.3 3.9e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG69107.1 - 0.00048 19.0 0.0 0.00072 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase HAP2-GCS1 PF10699.9 GBG69108.1 - 0.076 13.0 1.0 0.12 12.3 1.0 1.3 1 0 0 1 1 1 0 Male gamete fusion factor Pkinase PF00069.25 GBG69109.1 - 1.8e-38 132.4 0.0 3.4e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG69109.1 - 1.8e-37 129.0 0.0 3e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG69109.1 - 4.6e-05 23.4 0.3 0.00013 22.0 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG69109.1 - 0.00071 18.5 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase CD34_antigen PF06365.12 GBG69109.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM82 PF15816.5 GBG69109.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 82 Peptidase_M18 PF02127.15 GBG69111.1 - 1.4e-137 459.0 0.2 7.7e-83 278.7 0.0 3.0 3 0 0 3 3 3 3 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GBG69111.1 - 0.0038 16.3 0.2 0.0066 15.5 0.2 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase SICA_C PF12879.7 GBG69112.1 - 0.015 15.3 0.4 0.027 14.5 0.4 1.5 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain NPBW PF15180.6 GBG69112.1 - 0.089 12.7 0.2 7 6.5 0.1 3.1 3 0 0 3 3 3 0 Neuropeptides B and W Integrase_H2C2 PF17921.1 GBG69113.1 - 0.0051 16.9 0.0 0.0087 16.1 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain SDA1 PF05285.12 GBG69113.1 - 0.48 9.8 23.7 0.64 9.4 23.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG69113.1 - 0.89 7.7 20.9 1.1 7.4 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG69113.1 - 3 6.5 5.3 3.5 6.3 5.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 GBG69114.1 - 1 8.6 31.8 1.6 7.9 31.8 1.3 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG69114.1 - 1.2 8.6 17.7 1.7 8.1 17.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Vfa1 PF08432.10 GBG69114.1 - 2.6 8.4 14.6 4.6 7.5 14.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 GBG69114.1 - 3.2 7.1 34.1 4.9 6.5 34.1 1.2 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG69114.1 - 4.7 7.4 21.2 8 6.7 21.2 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.14 GBG69114.1 - 5.6 5.1 25.4 7.5 4.7 25.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG69114.1 - 8.4 5.0 14.3 12 4.6 14.3 1.2 1 0 0 1 1 1 0 Presenilin ToxN_toxin PF13958.6 GBG69115.1 - 0.19 11.9 0.1 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system Fasciclin PF02469.22 GBG69116.1 - 0.033 14.4 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Fasciclin domain Glyco_hydro_127 PF07944.12 GBG69117.1 - 1.7e-121 406.3 0.0 2.2e-121 405.9 0.0 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 AbfB PF05270.13 GBG69117.1 - 4e-07 30.1 0.0 9.9e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Macoilin PF09726.9 GBG69117.1 - 0.44 9.0 1.9 0.64 8.5 1.9 1.1 1 0 0 1 1 1 0 Macoilin family BHD_3 PF10405.9 GBG69118.1 - 4.9e-24 84.5 0.1 1.2e-23 83.3 0.1 1.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 GBG69118.1 - 1.3e-16 61.3 0.3 1.3e-16 61.3 0.3 4.1 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.15 GBG69118.1 - 7.3e-14 51.7 0.0 2.1e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 GBG69118.1 - 9.7e-14 50.9 0.0 1.8e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 GBG69118.1 - 1.7e-05 25.2 5.1 0.0046 17.4 0.0 4.2 5 0 0 5 5 5 2 Transglutaminase-like superfamily DDE_Tnp_4 PF13359.6 GBG69119.1 - 6.2e-15 55.2 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69119.1 - 2.7e-08 33.7 0.0 5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG69120.1 - 8.6e-07 29.3 1.8 8.6e-07 29.3 1.8 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG69120.1 - 0.15 12.3 0.5 0.27 11.5 0.5 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain PGA2 PF07543.12 GBG69120.1 - 0.16 11.9 1.2 0.34 10.9 1.2 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 Hydrolase_4 PF12146.8 GBG69121.1 - 5.5e-13 48.7 0.1 2.9e-08 33.3 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GBG69121.1 - 2e-11 43.8 0.0 3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GBG69121.1 - 3.8e-11 43.1 0.1 1.9e-06 27.7 0.0 2.6 2 1 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG69121.1 - 1.1e-08 36.0 0.0 2.7e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GBG69121.1 - 2.2e-07 30.7 0.0 2.8e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 GBG69121.1 - 7.3e-07 29.0 3.2 0.001 18.7 0.0 2.7 3 0 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 GBG69121.1 - 2.2e-05 23.3 0.0 0.0049 15.6 0.1 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 GBG69121.1 - 6.6e-05 22.9 0.0 0.0074 16.2 0.0 2.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 GBG69121.1 - 0.0004 19.0 0.0 0.00058 18.5 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II FSH1 PF03959.13 GBG69121.1 - 0.00072 19.3 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 GBG69121.1 - 0.00089 19.1 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 GBG69121.1 - 0.0023 17.8 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.11 GBG69121.1 - 0.0043 15.9 0.0 0.0063 15.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Pex14_N PF04695.13 GBG69121.1 - 0.017 15.8 0.4 0.026 15.2 0.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lipase_3 PF01764.25 GBG69121.1 - 0.039 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 GBG69121.1 - 0.05 13.2 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase UbiA PF01040.18 GBG69123.1 - 1e-47 162.6 20.9 1e-47 162.6 20.9 1.7 2 0 0 2 2 2 1 UbiA prenyltransferase family RVP_2 PF08284.11 GBG69124.1 - 1.7e-07 31.1 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69124.1 - 4.1e-05 24.2 0.0 0.0001 22.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69124.1 - 0.00018 22.0 0.0 0.00054 20.5 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG69124.1 - 0.0011 18.7 0.0 0.0029 17.4 0.0 1.7 2 0 0 2 2 2 1 Putative peptidase (DUF1758) TadF PF16964.5 GBG69125.1 - 1.2 8.8 4.5 2 8.1 4.5 1.3 1 0 0 1 1 1 0 Putative tight adherence pilin protein F RT_RNaseH_2 PF17919.1 GBG69126.1 - 1.5e-18 66.7 0.0 2.9e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69126.1 - 9.3e-13 48.2 0.1 1.5e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69126.1 - 3.8e-08 33.6 0.0 7.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CvfB_WH PF17783.1 GBG69127.1 - 0.0012 18.6 0.0 0.0039 16.9 0.0 1.9 1 0 0 1 1 1 1 CvfB-like winged helix domain RT_RNaseH_2 PF17919.1 GBG69128.1 - 3.4e-24 84.8 0.0 1.1e-23 83.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69128.1 - 4.4e-22 78.4 0.0 1.3e-21 76.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69128.1 - 6.8e-19 68.3 0.1 1.3e-18 67.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG69128.1 - 6.6e-18 64.6 0.5 3.1e-17 62.4 0.4 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG69128.1 - 3.9e-09 36.7 0.0 1.9e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG69128.1 - 0.00047 20.8 0.0 0.0014 19.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69128.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG69128.1 - 0.0011 19.5 0.0 0.0032 18.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG69128.1 - 0.0013 18.6 0.1 0.0033 17.3 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG69128.1 - 0.042 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG69128.1 - 0.095 12.9 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Exostosin PF03016.15 GBG69130.1 - 4.1e-39 134.6 0.0 6.3e-38 130.7 0.0 2.3 1 1 0 1 1 1 1 Exostosin family ADK PF00406.22 GBG69130.1 - 9e-08 32.4 0.0 0.004 17.3 0.0 2.6 2 0 0 2 2 2 2 Adenylate kinase AAA_18 PF13238.6 GBG69130.1 - 0.015 15.8 0.4 0.056 14.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GBG69130.1 - 0.02 15.1 0.0 0.074 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.13 GBG69130.1 - 0.02 15.2 45.0 0.012 15.9 10.5 3.8 3 0 0 3 3 3 0 EGF-like domain Hydin_ADK PF17213.3 GBG69130.1 - 0.049 13.9 0.0 0.049 13.9 0.0 3.6 3 1 0 3 3 3 0 Hydin Adenylate kinase-like domain RVT_1 PF00078.27 GBG69132.1 - 0.0024 17.4 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG69133.1 - 1.3e-28 100.0 0.2 2.8e-28 98.9 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69133.1 - 1.5e-11 44.2 0.0 4.7e-11 42.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG69133.1 - 5.9e-09 36.5 0.0 1.5e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69133.1 - 5.6e-08 33.2 0.0 1.4e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG69133.1 - 4.3e-05 23.3 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG69133.1 - 8.5e-05 22.3 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG69133.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG69133.1 - 0.039 14.2 5.5 0.041 14.2 0.1 3.9 3 1 1 4 4 4 0 Retrotransposon gag protein Fzo_mitofusin PF04799.13 GBG69133.1 - 0.66 9.5 2.7 41 3.7 0.1 3.3 3 0 0 3 3 3 0 fzo-like conserved region SNAPc19 PF15497.6 GBG69133.1 - 0.88 10.1 3.2 7.2 7.1 0.0 3.0 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 CLZ PF16526.5 GBG69133.1 - 4.7 7.6 12.5 0.54 10.7 0.5 4.3 5 1 1 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Chromo PF00385.24 GBG69134.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF659 PF04937.15 GBG69135.1 - 5.9e-18 65.2 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG69136.1 - 0.0003 21.3 0.1 0.00098 19.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG69136.1 - 0.00086 19.1 0.1 0.0015 18.3 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69136.1 - 0.006 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69136.1 - 0.011 16.4 0.1 0.028 15.0 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG69136.1 - 0.32 11.1 2.0 0.58 10.3 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG69137.1 - 1.7e-20 73.5 0.0 2.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FXMRP1_C_core PF12235.8 GBG69138.1 - 7.8 7.1 13.3 0.54 10.9 7.3 1.9 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal GRP PF07172.11 GBG69138.1 - 9.4 7.0 21.9 16 6.2 21.9 1.5 1 0 0 1 1 1 0 Glycine rich protein family Dimer_Tnp_hAT PF05699.14 GBG69139.1 - 7.2e-05 22.5 0.9 0.00016 21.4 0.9 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Protamine_like PF06382.11 GBG69140.1 - 0.13 12.5 11.6 0.28 11.4 0.2 3.4 3 0 0 3 3 3 0 Protamine and protamine like Neur_chan_memb PF02932.16 GBG69142.1 - 0.14 12.2 0.3 0.26 11.3 0.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 GBG69142.1 - 0.28 11.3 1.6 0.28 11.4 0.5 1.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Sugar_tr PF00083.24 GBG69143.1 - 6.8e-32 110.9 11.1 5.6e-20 71.6 5.7 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 GBG69143.1 - 2.9e-18 65.9 27.1 6.2e-11 41.8 12.4 3.4 3 0 0 3 3 3 3 Major Facilitator Superfamily Mito_fiss_reg PF05308.11 GBG69143.1 - 0.29 11.2 43.0 0.32 11.0 4.6 4.6 4 0 0 4 4 4 0 Mitochondrial fission regulator RED_C PF07807.11 GBG69144.1 - 0.31 11.5 6.2 0.5 10.8 6.2 1.2 1 0 0 1 1 1 0 RED-like protein C-terminal region Cwf_Cwc_15 PF04889.12 GBG69144.1 - 1.5 8.5 12.6 2.1 8.0 12.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG69144.1 - 1.8 6.7 17.0 2.1 6.4 17.0 1.0 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 GBG69144.1 - 5.7 6.9 28.0 8.1 6.4 28.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 GBG69144.1 - 7.3 5.9 18.2 8.6 5.7 18.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG69144.1 - 8.6 4.5 15.5 11 4.2 15.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG69145.1 - 2.8e-28 97.9 0.0 4.9e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69145.1 - 7.6e-27 94.3 0.1 1.1e-26 93.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69145.1 - 5.1e-25 87.8 0.0 9.9e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sec3_C PF09763.9 GBG69146.1 - 6.4e-89 299.2 0.0 1.4e-87 294.8 0.0 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 GBG69146.1 - 4.7e-11 42.7 0.1 9.9e-11 41.6 0.1 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 GBG69146.1 - 3.5e-10 39.2 2.6 6.1e-09 35.1 0.3 2.2 2 0 0 2 2 2 2 Vps52 / Sac2 family CCDC-167 PF15188.6 GBG69146.1 - 0.059 13.7 0.2 2.2 8.7 0.1 2.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 CENP-F_leu_zip PF10473.9 GBG69146.1 - 0.077 13.0 4.6 0.28 11.2 2.3 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bd3614-deam PF14439.6 GBG69147.1 - 0.058 13.5 1.4 0.073 13.2 0.5 1.7 2 0 0 2 2 2 0 Bd3614-like deaminase Fringe PF02434.16 GBG69148.1 - 3.7e-08 33.1 0.0 1.3e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Fringe-like RXT2_N PF08595.11 GBG69148.1 - 3.4 7.7 8.1 0.47 10.5 2.1 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal NARP1 PF12569.8 GBG69148.1 - 3.5 6.4 8.0 5.4 5.8 8.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 LisH_2 PF16045.5 GBG69149.1 - 1.3e-12 46.5 0.4 3.4e-12 45.2 0.3 1.8 2 0 0 2 2 2 1 LisH Peptidase_C48 PF02902.19 GBG69149.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LisH PF08513.11 GBG69149.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 LisH FOP_dimer PF09398.10 GBG69149.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 FOP N terminal dimerisation domain Apolipoprotein PF01442.18 GBG69150.1 - 5.4e-21 75.3 108.7 7.1e-09 35.8 31.3 6.1 3 1 2 5 5 5 5 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GBG69150.1 - 2.3e-17 63.3 126.4 0.00068 20.1 10.6 11.5 4 3 5 9 9 9 8 YtxH-like protein DUF883 PF05957.13 GBG69150.1 - 2.4e-09 37.7 115.8 0.016 15.8 8.5 11.2 5 2 6 11 11 11 7 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.16 GBG69150.1 - 7e-07 29.2 148.2 0.002 18.2 20.8 13.2 6 2 7 13 13 13 9 Late embryogenesis abundant protein ApoLp-III PF07464.11 GBG69150.1 - 5.2e-06 26.6 67.9 0.046 13.8 4.5 6.3 5 1 2 7 7 7 5 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 GBG69150.1 - 0.11 12.5 3.2 60 3.7 0.0 4.2 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0181 PF03701.14 GBG69150.1 - 0.45 10.2 3.8 1.4 8.6 3.8 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) tRNA-synt_2b PF00587.25 GBG69151.1 - 7.1e-22 78.2 0.0 9.5e-15 55.0 0.0 2.5 1 1 1 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GBG69151.1 - 7.6e-18 64.5 0.0 1.9e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 GBG69151.1 - 2.1e-12 46.9 0.0 6.5e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain zf-RVT PF13966.6 GBG69152.1 - 6.8e-11 42.7 1.4 6.8e-11 42.7 1.4 3.4 4 0 0 4 4 4 1 zinc-binding in reverse transcriptase Ribonuclease_3 PF00636.26 GBG69153.1 - 3.4e-14 53.3 0.0 9.4e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GBG69153.1 - 6.3e-11 42.5 0.0 8.6e-09 35.6 0.0 2.7 3 0 0 3 3 3 1 Ribonuclease-III-like dsrm PF00035.26 GBG69153.1 - 2.3e-08 34.6 0.0 6.4e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif Myc_N PF01056.18 GBG69153.1 - 0.016 15.1 0.8 0.016 15.1 0.8 3.3 2 1 1 3 3 3 0 Myc amino-terminal region DND1_DSRM PF14709.7 GBG69153.1 - 0.023 14.9 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Integrase_H2C2 PF17921.1 GBG69154.1 - 2.3e-14 53.2 0.2 6e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG69154.1 - 0.00019 21.6 2.9 0.029 14.7 0.0 3.2 2 1 0 2 2 2 2 Retrotransposon gag protein zf-CCHC_5 PF14787.6 GBG69154.1 - 0.0073 16.0 2.2 0.016 14.9 2.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger rve PF00665.26 GBG69154.1 - 0.031 14.5 0.0 0.093 12.9 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain BCL_N PF04714.13 GBG69154.1 - 8.3 6.6 8.7 10 6.3 1.8 3.9 3 0 0 3 3 3 0 BCL7, N-terminal conserver region Ribul_P_3_epim PF00834.19 GBG69155.1 - 3.6e-88 294.1 0.2 4.5e-88 293.8 0.2 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family BKACE PF05853.12 GBG69155.1 - 0.0084 15.4 0.0 0.093 12.0 0.0 2.2 2 0 0 2 2 2 1 beta-keto acid cleavage enzyme Frataxin_Cyay PF01491.16 GBG69156.1 - 9.2e-35 119.0 0.0 1.6e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Frataxin-like domain Herpes_ICP4_N PF03584.15 GBG69156.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Mito_fiss_reg PF05308.11 GBG69156.1 - 0.067 13.3 2.8 0.23 11.5 1.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Phage_Gp23 PF10669.9 GBG69156.1 - 0.12 12.7 0.7 0.2 12.0 0.7 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CAP_N PF01213.19 GBG69156.1 - 0.17 11.3 3.4 0.29 10.6 3.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG69156.1 - 0.51 10.4 3.6 1.3 9.1 3.6 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Auts2 PF15336.6 GBG69156.1 - 2.8 8.0 9.1 0.41 10.7 2.7 2.3 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein Nmad5 PF18757.1 GBG69158.1 - 1.3 9.2 8.9 0.12 12.6 3.9 1.8 2 1 0 2 2 2 0 Nucleotide modification associated domain 5 Pkinase_Tyr PF07714.17 GBG69161.1 - 6.7e-37 127.2 0.0 1.6e-36 126.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG69161.1 - 5.4e-33 114.5 0.0 8.2e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CDC45 PF02724.14 GBG69162.1 - 5.7 5.1 11.8 8.7 4.5 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG69164.1 - 8.2e-55 185.7 0.1 1.1e-29 103.6 0.0 3.2 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69164.1 - 3e-41 139.5 0.0 6e-25 87.2 0.0 4.1 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69164.1 - 4.1e-40 136.3 0.2 1.9e-22 79.5 0.0 3.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69164.1 - 2e-35 120.7 2.7 4.8e-18 65.0 0.3 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain TPR_1 PF00515.28 GBG69164.1 - 1.9e-16 59.1 4.7 0.0019 17.9 0.1 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG69164.1 - 3.4e-15 55.5 17.6 0.07 12.8 0.0 8.7 7 1 1 8 8 8 4 TPR repeat rve PF00665.26 GBG69164.1 - 7.8e-14 51.9 0.0 3.2e-13 49.9 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain TPR_2 PF07719.17 GBG69164.1 - 1.7e-10 40.1 31.0 0.014 15.4 0.4 10.6 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG69164.1 - 8.4e-10 38.1 9.0 0.06 13.6 0.1 7.5 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG69164.1 - 1.1e-07 32.3 53.3 0.0029 18.1 0.0 12.5 13 1 1 14 14 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 GBG69164.1 - 6.4e-07 29.0 20.6 0.052 13.6 0.4 8.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG69164.1 - 2.9e-06 27.6 16.3 10 7.0 0.0 9.2 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG69164.1 - 4e-06 27.2 61.6 0.33 11.9 0.0 14.8 14 2 1 16 16 10 4 Tetratricopeptide repeat Asp_protease_2 PF13650.6 GBG69164.1 - 0.00015 22.3 0.0 0.0005 20.6 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease TPR_10 PF13374.6 GBG69164.1 - 0.00019 21.2 25.1 0.46 10.4 0.2 7.4 6 0 0 6 6 5 2 Tetratricopeptide repeat Retrotrans_gag PF03732.17 GBG69164.1 - 0.00034 20.8 11.8 0.013 15.8 0.0 5.1 5 0 0 5 5 3 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG69164.1 - 0.0005 20.2 0.1 0.29 11.4 0.0 3.0 2 0 0 2 2 2 1 H2C2 zinc finger TPR_12 PF13424.6 GBG69164.1 - 0.00079 19.7 68.2 0.046 14.0 0.4 11.3 11 0 0 11 11 9 6 Tetratricopeptide repeat gag-asp_proteas PF13975.6 GBG69164.1 - 0.001 19.5 0.0 0.0032 18.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG69164.1 - 0.008 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG69164.1 - 0.0093 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease TPR_16 PF13432.6 GBG69164.1 - 0.01 16.4 68.7 0.035 14.8 0.2 12.2 10 2 2 12 12 11 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG69164.1 - 0.69 10.4 17.5 21 5.8 0.0 8.6 10 0 0 10 10 7 0 Tetratricopeptide repeat HATPase_c PF02518.26 GBG69165.1 - 2e-18 66.9 0.0 1.3e-12 48.2 0.0 3.1 2 1 1 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GBG69165.1 - 7.4e-18 64.8 2.2 1.2e-17 64.1 0.7 2.1 2 0 0 2 2 2 1 Response regulator receiver domain CHASE PF03924.13 GBG69165.1 - 9.2e-08 32.2 0.0 2.2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 CHASE domain HisKA PF00512.25 GBG69165.1 - 5.9e-06 26.2 0.1 1.4e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain IlvGEDA_leader PF08046.11 GBG69165.1 - 1.5 8.3 7.5 3.7 7.1 7.5 1.6 1 0 0 1 1 1 0 IlvGEDA operon leader peptide Elongin_A PF06881.11 GBG69166.1 - 1.7e-13 51.0 0.1 1.7e-13 51.0 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3640 PF12342.8 GBG69166.1 - 0.42 10.4 4.1 0.35 10.6 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) CAML PF14963.6 GBG69166.1 - 6.3 6.8 5.7 1.8 8.6 1.3 2.1 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Mesd PF10185.9 GBG69167.1 - 3.1e-07 30.4 0.0 4.1e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor RVT_1 PF00078.27 GBG69168.1 - 0.00032 20.3 0.0 0.00078 19.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG69168.1 - 0.0041 17.4 1.8 0.018 15.3 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4404 PF14357.6 GBG69168.1 - 0.99 10.1 4.4 4.6 8.0 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) FUSC PF04632.12 GBG69168.1 - 4.7 5.6 8.8 1.7 7.1 3.4 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family DDE_Tnp_4 PF13359.6 GBG69169.1 - 4.9e-31 107.5 0.0 8e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69169.1 - 2e-15 57.0 0.0 2.8e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG69169.1 - 1.5e-05 24.7 1.4 0.002 17.8 0.0 2.6 2 1 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG69169.1 - 0.054 13.9 1.9 2 8.8 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG69170.1 - 4.5e-07 30.1 1.9 1e-06 29.0 1.9 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG69170.1 - 0.00089 19.3 0.6 0.0016 18.4 0.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG69170.1 - 0.0097 16.1 0.1 0.063 13.5 0.0 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain Sacchrp_dh_NADP PF03435.18 GBG69171.1 - 0.0016 18.7 0.0 0.57 10.5 0.0 2.3 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 GBG69171.1 - 0.0056 16.3 0.1 2.2 7.8 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family Apt1 PF10351.9 GBG69171.1 - 0.69 8.7 6.7 0.85 8.4 6.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CtnDOT_TraJ PF07863.11 GBG69171.1 - 1.9 9.2 6.7 26 5.6 0.7 2.9 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Pex14_N PF04695.13 GBG69171.1 - 2.7 8.6 15.3 1.7 9.3 1.9 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.9 GBG69171.1 - 5.9 6.0 17.1 7.5 5.6 17.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DEAD PF00270.29 GBG69173.1 - 2.4e-42 144.7 0.0 5.8e-42 143.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG69173.1 - 5.5e-20 71.8 0.0 3.9e-19 69.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-HIT PF04438.16 GBG69173.1 - 5e-08 32.7 1.4 9.4e-08 31.8 1.4 1.5 1 0 0 1 1 1 1 HIT zinc finger kleA_kleC PF17383.2 GBG69174.1 - 0.053 13.8 4.0 0.2 12.0 4.0 1.9 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A PRKG1_interact PF15898.5 GBG69174.1 - 0.18 12.7 11.6 0.34 11.8 9.9 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 GBG69174.1 - 0.33 11.6 11.2 1.1 9.9 1.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA KIAA1430 PF13879.6 GBG69174.1 - 0.37 11.6 4.8 0.8 10.5 4.8 1.5 1 0 0 1 1 1 0 KIAA1430 homologue TSC22 PF01166.18 GBG69174.1 - 1.3 9.4 6.2 15 6.0 1.9 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family RT_RNaseH PF17917.1 GBG69175.1 - 1.1e-40 138.1 2.5 1.8e-19 70.0 0.7 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69175.1 - 1.8e-23 82.5 2.2 2.9e-11 43.3 0.1 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69175.1 - 2.9e-19 68.9 0.2 6.4e-19 67.8 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69175.1 - 6.3e-14 52.2 0.0 2.9e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG69175.1 - 0.00039 20.6 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG69175.1 - 0.00078 19.2 1.3 0.015 15.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Phage_lysozyme PF00959.19 GBG69175.1 - 0.07 13.6 1.0 1.8 9.1 0.1 2.9 1 1 0 2 2 2 0 Phage lysozyme URO-D PF01208.17 GBG69176.1 - 2.8e-104 349.0 0.0 3.6e-104 348.6 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) RT_RNaseH_2 PF17919.1 GBG69177.1 - 1e-30 105.7 0.0 2.3e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69177.1 - 6.4e-28 97.8 0.0 1.3e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69177.1 - 5.3e-26 91.0 0.1 1.1e-25 89.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rhamno_transf PF11316.8 GBG69177.1 - 0.056 12.8 0.6 0.42 10.0 0.0 2.3 2 0 0 2 2 2 0 Putative rhamnosyl transferase Phage_GPO PF05929.11 GBG69177.1 - 3.3 7.2 6.2 9.7 5.7 0.0 2.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Glyco_hydro_19 PF00182.19 GBG69178.1 - 8.8e-57 192.7 0.1 1.5e-56 191.9 0.1 1.3 1 0 0 1 1 1 1 Chitinase class I CBM_14 PF01607.24 GBG69178.1 - 1.2e-11 44.6 5.3 1.2e-11 44.6 5.3 2.0 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain RVT_1 PF00078.27 GBG69179.1 - 1.5e-11 44.3 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG69181.1 - 1.2e-29 103.5 0.2 2.3e-29 102.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69181.1 - 9.3e-24 83.7 0.0 1.6e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69181.1 - 9.2e-22 77.0 0.0 2.1e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69182.1 - 4.6e-24 84.7 0.0 8e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69182.1 - 5.6e-22 77.7 0.0 1.1e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69182.1 - 7.5e-16 58.3 0.0 2.1e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrin_b_cyt PF08725.11 GBG69182.1 - 0.098 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Glyco_hydro_19 PF00182.19 GBG69183.1 - 9e-54 182.8 0.6 1.3e-53 182.3 0.6 1.2 1 0 0 1 1 1 1 Chitinase class I CBM_14 PF01607.24 GBG69183.1 - 9.1e-14 51.4 5.5 9.1e-14 51.4 5.5 2.1 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Mito_fiss_reg PF05308.11 GBG69183.1 - 1.8 8.6 7.7 3 7.9 7.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator FlaC_arch PF05377.11 GBG69184.1 - 0.0053 17.1 2.7 0.0095 16.3 1.3 2.3 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) UPF0449 PF15136.6 GBG69184.1 - 0.44 11.1 10.2 0.65 10.5 0.2 4.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 DUF5320 PF17253.2 GBG69184.1 - 1.7 9.8 11.4 0.7 11.0 0.2 3.7 2 1 1 3 3 3 0 Family of unknown function (DUF5320) Syntaxin_2 PF14523.6 GBG69184.1 - 3 8.2 13.4 12 6.4 0.5 4.1 3 1 0 3 3 3 0 Syntaxin-like protein Syntaxin-6_N PF09177.11 GBG69184.1 - 4.3 8.0 12.4 11 6.6 6.6 3.6 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Glyco_hydro_19 PF00182.19 GBG69185.1 - 8.6e-27 94.5 0.0 9.2e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Chitinase class I SDA1 PF05285.12 GBG69186.1 - 1.3 8.4 22.2 1.8 7.9 22.2 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG69186.1 - 2.4 7.4 24.6 3.4 6.9 24.6 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG69186.1 - 4.3 5.5 16.9 6.2 5.0 16.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG69186.1 - 4.8 6.6 15.0 8.2 5.9 15.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cwf_Cwc_15 PF04889.12 GBG69186.1 - 6.5 6.4 19.3 12 5.5 19.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG69186.1 - 8.3 4.5 23.2 13 3.9 23.2 1.2 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 GBG69186.1 - 8.4 5.7 22.7 17 4.7 22.7 1.6 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) LAP1C PF05609.12 GBG69186.1 - 9 5.3 13.9 13 4.7 13.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Glyco_hydro_19 PF00182.19 GBG69188.1 - 2.5e-26 93.0 0.0 3.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Chitinase class I Glyco_hydro_19 PF00182.19 GBG69189.1 - 3.4e-26 92.6 0.0 4.7e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Chitinase class I RVT_1 PF00078.27 GBG69190.1 - 2.1e-29 102.6 0.1 3.7e-29 101.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69190.1 - 5e-26 90.7 0.0 1e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69190.1 - 9.9e-23 80.4 0.0 2e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG69190.1 - 1.6e-08 35.1 0.0 3.6e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69190.1 - 1.8e-07 31.6 0.0 4.5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG69190.1 - 6.4e-07 29.2 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG69190.1 - 0.00013 21.7 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG69190.1 - 0.043 12.9 0.2 11 5.0 0.0 2.4 2 1 0 2 2 2 0 Autophagy protein Apg17 Glyco_hydro_47 PF01532.20 GBG69191.1 - 4.9e-160 533.4 0.0 5.5e-125 417.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 tify PF06200.14 GBG69191.1 - 0.28 10.5 0.7 18 4.7 0.0 2.4 2 0 0 2 2 2 0 tify domain 2OG-FeII_Oxy_2 PF13532.6 GBG69192.1 - 1.7e-27 96.9 0.0 3.3e-17 63.3 0.0 2.3 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Thioredoxin PF00085.20 GBG69193.1 - 5.4e-258 835.8 18.8 1.7e-30 105.0 0.1 9.2 9 0 0 9 9 9 9 Thioredoxin Thioredoxin_8 PF13905.6 GBG69193.1 - 5.9e-41 138.7 5.1 0.00033 20.9 0.0 9.7 9 0 0 9 9 9 9 Thioredoxin-like Thioredoxin_2 PF13098.6 GBG69193.1 - 6.7e-36 123.1 22.0 0.00015 22.2 0.1 9.5 9 0 0 9 9 9 9 Thioredoxin-like domain Thioredoxin_6 PF13848.6 GBG69193.1 - 3e-17 63.1 2.6 0.45 10.4 0.0 9.2 9 0 0 9 9 9 4 Thioredoxin-like domain OST3_OST6 PF04756.13 GBG69193.1 - 3.6e-15 56.1 8.8 0.092 12.1 0.0 8.1 6 2 2 8 8 8 5 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 GBG69193.1 - 1.6e-14 53.9 18.1 0.38 10.7 0.0 9.0 9 0 0 9 9 9 5 AhpC/TSA family Thioredoxin_3 PF13192.6 GBG69193.1 - 8.4e-13 48.2 7.2 0.22 11.6 0.0 8.3 8 0 0 8 8 8 3 Thioredoxin domain DUF5017 PF16409.5 GBG69193.1 - 3.6e-10 39.6 1.7 0.81 9.1 0.0 7.8 9 0 0 9 9 9 2 Domain of unknown function (DUF5017) Thioredoxin_7 PF13899.6 GBG69193.1 - 2.2e-08 34.1 23.8 5.3 7.3 0.1 8.7 8 0 0 8 8 8 2 Thioredoxin-like Redoxin PF08534.10 GBG69193.1 - 9e-08 32.0 24.5 2.8 7.7 0.1 9.0 9 0 0 9 9 9 3 Redoxin TraF PF13728.6 GBG69193.1 - 2.2e-06 27.7 8.3 2.2 8.1 0.0 7.8 9 0 0 9 9 8 2 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 GBG69193.1 - 0.00066 19.9 15.8 24 5.0 0.1 9.5 9 3 1 10 10 10 0 Thioredoxin Flu_B_NS1 PF02942.14 GBG69193.1 - 0.024 13.7 0.0 23 3.9 0.0 4.5 6 0 0 6 6 6 0 Influenza B non-structural protein (NS1) U79_P34 PF03064.16 GBG69193.1 - 0.12 11.7 0.1 14 5.0 0.0 3.6 4 0 0 4 4 4 0 HSV U79 / HCMV P34 Prophage_tail PF06605.11 GBG69193.1 - 0.21 10.8 2.6 13 4.9 0.1 3.1 3 0 0 3 3 3 0 Prophage endopeptidase tail PBECR2 PF18810.1 GBG69193.1 - 2.7 8.3 8.4 86 3.5 0.0 6.3 9 0 0 9 9 9 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 TMEM82 PF15816.5 GBG69193.1 - 5.3 5.9 9.6 63 2.4 0.0 5.4 7 0 0 7 7 7 0 Transmembrane protein 82 YgbA_NO PF11756.8 GBG69193.1 - 9 6.7 16.1 13 6.2 0.1 5.0 6 0 0 6 6 4 0 Nitrous oxide-stimulated promoter RT_RNaseH_2 PF17919.1 GBG69194.1 - 9.5e-24 83.3 0.0 2.2e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69194.1 - 1.2e-21 76.9 0.0 2.6e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG69194.1 - 3.6e-05 24.0 0.8 0.0084 16.4 0.0 3.4 2 0 0 2 2 2 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG69194.1 - 0.00046 20.2 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG69194.1 - 0.022 14.3 0.1 0.061 12.8 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) MFAP1 PF06991.11 GBG69197.1 - 0.92 9.3 10.7 1.7 8.4 10.7 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DUF2927 PF11150.8 GBG69197.1 - 1.3 9.0 6.0 1.6 8.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2927) RVT_1 PF00078.27 GBG69198.1 - 2.4e-31 109.0 0.1 3.7e-31 108.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69198.1 - 7.1e-29 99.8 0.0 1.7e-28 98.6 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69198.1 - 5.7e-24 84.4 0.0 1.2e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2990 PF11693.8 GBG69198.1 - 0.066 13.4 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) AMPK1_CBM PF16561.5 GBG69199.1 - 2e-08 34.3 0.0 4.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DDE_Tnp_4 PF13359.6 GBG69200.1 - 9.9e-21 74.0 0.0 1.8e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69200.1 - 2.5e-08 33.8 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG69201.1 - 2.1e-09 37.7 1.9 4.4e-09 36.6 0.3 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain YccJ PF13993.6 GBG69201.1 - 0.29 11.5 2.1 1.5 9.2 0.1 2.4 2 0 0 2 2 2 0 YccJ-like protein Pyrophosphatase PF00719.19 GBG69202.1 - 6.2e-54 182.1 0.0 7.2e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Glyco_hydro_47 PF01532.20 GBG69203.1 - 6.8e-150 500.0 0.0 8.4e-150 499.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CopD PF05425.13 GBG69203.1 - 0.04 14.3 0.4 0.078 13.4 0.4 1.4 1 0 0 1 1 1 0 Copper resistance protein D Asp_protease_2 PF13650.6 GBG69204.1 - 1.9e-06 28.4 0.0 4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69204.1 - 2.8e-06 27.8 0.0 5.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG69204.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69204.1 - 0.088 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Na_Ca_ex PF01699.24 GBG69205.1 - 1.2e-17 64.3 24.9 3.6e-11 43.3 16.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_7 PF13499.6 GBG69205.1 - 2.2e-05 24.8 0.2 5.3e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GBG69205.1 - 0.001 18.4 0.4 0.0044 16.5 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 GBG69205.1 - 0.0015 17.9 1.9 0.0021 17.4 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GBG69205.1 - 0.0051 16.7 0.5 0.016 15.1 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 GBG69205.1 - 0.046 13.6 0.4 0.34 10.8 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain pair DUF3917 PF13055.6 GBG69205.1 - 0.55 10.7 5.9 2.8 8.4 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3917) DUF4710 PF15828.5 GBG69205.1 - 0.64 10.2 0.0 0.64 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) COPI_C PF06957.11 GBG69205.1 - 3 6.5 9.5 5.2 5.7 1.3 2.1 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus CDC45 PF02724.14 GBG69205.1 - 5.7 5.1 14.7 0.3 9.3 4.7 2.2 2 0 0 2 2 2 0 CDC45-like protein Myb_DNA-bind_4 PF13837.6 GBG69206.1 - 0.00014 22.2 0.9 0.00046 20.5 0.2 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG69208.1 - 3.2e-29 101.6 0.0 7.6e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69208.1 - 1.3e-12 47.8 0.0 2.3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG69208.1 - 0.00011 21.9 0.1 0.53 9.9 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG69209.1 - 7.9e-08 32.6 2.9 7.9e-08 32.6 2.9 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG69209.1 - 0.00059 20.0 0.8 0.0019 18.4 0.8 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG69209.1 - 0.0029 17.9 2.4 0.018 15.4 0.8 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG69209.1 - 0.03 14.4 1.5 0.061 13.4 1.5 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG69210.1 - 6.6e-20 71.4 0.0 1.4e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69210.1 - 7.2e-11 42.1 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG69210.1 - 0.0035 17.0 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain MFS_5 PF05631.14 GBG69212.1 - 1.5e-148 494.4 12.8 1.9e-148 494.1 12.8 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GBG69212.1 - 1.9e-17 63.2 33.1 1.8e-16 60.1 25.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily SAYSvFN PF10260.9 GBG69212.1 - 0.12 12.3 3.7 0.13 12.2 0.5 2.8 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) Beta_helix PF13229.6 GBG69215.1 - 2e-06 27.7 0.6 0.0027 17.6 0.1 2.2 1 1 1 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG69215.1 - 1.6e-05 25.1 0.3 1.6 9.3 0.0 3.9 3 0 0 3 3 3 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TolA_bind_tri PF16331.5 GBG69216.1 - 0.087 12.9 4.8 0.12 12.5 0.1 3.0 2 2 1 3 3 3 0 TolA binding protein trimerisation Cnn_1N PF07989.11 GBG69216.1 - 0.14 12.3 15.3 1.1 9.4 5.1 3.7 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 SOAR PF16533.5 GBG69216.1 - 0.2 11.6 8.0 0.048 13.6 3.6 2.2 2 1 0 2 2 2 0 STIM1 Orai1-activating region YabA PF06156.13 GBG69216.1 - 0.63 10.7 5.5 29 5.4 2.8 2.9 1 1 0 2 2 2 0 Initiation control protein YabA DUF2730 PF10805.8 GBG69216.1 - 0.65 10.1 5.5 0.52 10.4 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 GBG69216.1 - 5.1 6.4 8.3 11 5.3 8.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Filament PF00038.21 GBG69216.1 - 8.4 5.9 20.7 0.34 10.5 0.9 2.6 2 1 0 2 2 2 0 Intermediate filament protein TMPIT PF07851.13 GBG69216.1 - 9.6 5.3 7.8 1.3 8.3 4.0 1.5 2 0 0 2 2 2 0 TMPIT-like protein Beta_helix PF13229.6 GBG69217.1 - 6.2e-07 29.4 0.8 1.6e-06 28.0 0.8 1.8 1 1 0 1 1 1 1 Right handed beta helix region Beta_helix PF13229.6 GBG69218.1 - 1.9e-07 31.1 3.4 0.00015 21.7 0.4 2.3 1 1 1 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG69218.1 - 1.1e-06 28.7 0.9 1.6 9.3 0.0 5.3 5 0 0 5 5 5 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NOG1_N PF17835.1 GBG69219.1 - 2.1e-32 112.3 0.1 3.2e-32 111.7 0.1 1.3 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 GBG69219.1 - 4.4e-20 71.2 0.0 8.4e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 GBG69219.1 - 4.5e-15 55.7 0.0 7.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG69219.1 - 4.8e-08 32.7 0.0 8.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 GBG69219.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RVT_1 PF00078.27 GBG69220.1 - 3.3e-30 105.2 0.0 5.1e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF577 PF04510.12 GBG69222.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF577) NUDE_C PF04880.13 GBG69222.1 - 0.21 12.1 3.8 0.33 11.4 3.8 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Ysc84 PF04366.12 GBG69223.1 - 1.5e-34 118.5 0.1 2.6e-34 117.8 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator RVT_1 PF00078.27 GBG69223.1 - 1.7e-28 99.7 0.0 2.6e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG69223.1 - 0.064 13.5 0.1 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Senescence_reg PF04520.13 GBG69223.1 - 0.84 10.5 5.8 0.33 11.8 2.8 1.8 2 0 0 2 2 2 0 Senescence regulator FYVE PF01363.21 GBG69224.1 - 1.5e-15 57.0 9.4 1.5e-15 57.0 9.4 2.9 2 1 1 3 3 3 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 GBG69224.1 - 2.1e-08 33.9 3.7 2.1e-08 33.9 3.7 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG69224.1 - 8e-08 32.5 5.0 8e-08 32.5 5.0 2.9 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG69224.1 - 1.8e-07 31.0 4.5 1.8e-07 31.0 4.5 2.8 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GBG69224.1 - 9.2e-06 25.7 4.5 9.2e-06 25.7 4.5 3.4 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GBG69224.1 - 1.5e-05 24.7 4.5 1.5e-05 24.7 4.5 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG69224.1 - 4e-05 23.6 1.1 4e-05 23.6 1.1 3.6 3 0 0 3 3 2 2 RING-type zinc-finger zf-RING_4 PF14570.6 GBG69224.1 - 9.2e-05 22.2 2.6 9.2e-05 22.2 2.6 3.1 2 1 0 2 2 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 GBG69224.1 - 0.00097 19.0 8.0 0.00097 19.0 8.0 2.8 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GBG69224.1 - 0.0017 18.2 4.8 0.0017 18.2 4.8 3.3 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 GBG69224.1 - 0.0047 17.0 3.2 0.0047 17.0 3.2 2.8 2 1 0 2 2 1 1 zinc RING finger of MSL2 FYVE_2 PF02318.16 GBG69224.1 - 0.02 15.1 5.2 0.02 15.1 5.2 2.7 3 0 0 3 3 2 0 FYVE-type zinc finger SIMPL PF04402.14 GBG69224.1 - 0.04 14.4 2.5 0.068 13.6 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Rtf2 PF04641.12 GBG69224.1 - 0.047 13.1 0.2 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger Baculo_IE-1 PF05290.11 GBG69224.1 - 0.12 12.3 2.0 0.34 10.8 2.0 1.8 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_11 PF17123.5 GBG69224.1 - 0.16 11.7 0.1 0.16 11.7 0.1 3.1 3 0 0 3 3 3 0 RING-like zinc finger DUF3039 PF11238.8 GBG69224.1 - 0.48 10.2 3.8 2.7 7.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) K_channel_TID PF07941.11 GBG69224.1 - 0.67 10.4 24.7 0.93 10.0 9.5 2.9 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain ATE_N PF04376.13 GBG69225.1 - 0.055 13.9 0.2 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus Topo_Zn_Ribbon PF08272.11 GBG69225.1 - 0.33 10.7 2.1 0.31 10.8 0.2 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like CCB2_CCB4 PF11152.8 GBG69227.1 - 5e-58 195.7 0.1 6.3e-58 195.3 0.1 1.1 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 ORC6 PF05460.13 GBG69228.1 - 0.22 10.8 2.9 0.42 9.8 0.1 2.3 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Integrase_H2C2 PF17921.1 GBG69229.1 - 3.3e-06 27.1 0.0 9.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG69229.1 - 4.9e-06 27.0 0.1 2e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69229.1 - 0.00013 22.5 0.0 0.00045 20.8 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG69229.1 - 0.00032 20.5 1.1 0.00062 19.6 1.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG69229.1 - 0.0016 18.7 0.0 0.005 17.1 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease TPR_MLP1_2 PF07926.12 GBG69229.1 - 2.1 8.4 8.1 1.9 8.5 5.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein gag-asp_proteas PF13975.6 GBG69230.1 - 1.7e-08 34.9 0.0 6.5e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG69230.1 - 5.3e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG69230.1 - 8.4e-05 23.1 0.0 0.00028 21.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG69230.1 - 0.00027 21.2 0.0 0.00065 20.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69231.1 - 2.5e-28 99.1 0.1 4.4e-28 98.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG69231.1 - 2e-25 89.3 0.0 3.7e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69231.1 - 6e-11 42.3 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein SDA1 PF05285.12 GBG69231.1 - 0.00028 20.4 7.7 0.00039 19.9 7.7 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG69231.1 - 0.044 12.1 9.2 0.06 11.6 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG69231.1 - 1.8 7.3 7.9 2.7 6.7 7.9 1.1 1 0 0 1 1 1 0 Presenilin FGF-BP1 PF06473.12 GBG69231.1 - 6.6 6.5 12.9 11 5.8 12.9 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Trypan_PARP PF05887.11 GBG69231.1 - 8.1 6.4 10.3 21 5.1 10.3 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RT_RNaseH_2 PF17919.1 GBG69232.1 - 7.1e-30 103.0 0.0 1.4e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69232.1 - 7.2e-29 100.9 0.1 1.2e-28 100.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69232.1 - 3.9e-19 68.9 0.0 7.1e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PGI PF00342.19 GBG69233.1 - 6.4e-206 684.7 0.0 7.1e-206 684.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Lac_bphage_repr PF06543.12 GBG69233.1 - 0.0081 16.1 0.3 3.2 7.8 0.0 2.4 1 1 1 2 2 2 2 Lactococcus bacteriophage repressor Rieske_2 PF13806.6 GBG69234.1 - 4.3e-10 39.4 0.0 5.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 GBG69234.1 - 5.4e-06 26.3 0.0 8.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain zinc_ribbon_5 PF13719.6 GBG69234.1 - 0.094 12.5 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 GBG69234.1 - 0.11 12.4 1.4 0.62 10.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 GBG69234.1 - 2 8.6 5.4 6 7.1 3.3 2.5 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RT_RNaseH_2 PF17919.1 GBG69235.1 - 2.9e-28 97.8 0.0 1.1e-27 96.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69235.1 - 2.7e-27 95.1 0.1 7.3e-27 93.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69235.1 - 1.8e-21 76.7 0.3 3.7e-14 52.8 0.2 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG69235.1 - 4.3e-19 68.4 0.9 9.6e-19 67.2 0.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69235.1 - 3.2e-10 40.2 0.0 9.6e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG69235.1 - 0.017 15.3 0.1 0.053 13.7 0.1 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG69235.1 - 0.071 12.7 1.0 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase SNARE_assoc PF09335.11 GBG69236.1 - 2.5e-23 82.8 9.4 8.2e-23 81.2 9.4 2.0 1 0 0 1 1 1 1 SNARE associated Golgi protein RVT_1 PF00078.27 GBG69236.1 - 2.5e-22 79.5 0.0 1.6e-09 37.6 0.0 3.4 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69236.1 - 7.9e-20 71.1 0.0 2.1e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69236.1 - 1.9e-18 66.3 0.0 3.9e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69236.1 - 6.9e-16 58.5 0.0 2.6e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Glyco_transf_64 PF09258.10 GBG69237.1 - 3.1e-64 216.6 0.0 4.9e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 GBG69237.1 - 0.0014 18.2 0.0 0.17 11.4 0.0 2.8 2 1 0 2 2 2 1 Glycosyl transferase family 8 CdiI_N PF18228.1 GBG69237.1 - 0.047 13.5 0.0 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 CdiI N-terminal domain PRIMA1 PF16101.5 GBG69237.1 - 0.27 11.3 8.9 0.66 10.0 8.9 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Integrase_H2C2 PF17921.1 GBG69238.1 - 5.2e-14 52.1 0.3 1.2e-13 50.9 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69238.1 - 1e-10 41.9 0.2 2.4e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG69238.1 - 0.02 15.1 0.7 0.051 13.8 0.7 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Bap31 PF05529.12 GBG69239.1 - 0.001 18.9 6.9 0.0016 18.3 6.9 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region RT_RNaseH PF17917.1 GBG69240.1 - 5e-25 87.8 0.4 9.4e-25 86.9 0.4 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69240.1 - 1.4e-20 73.2 0.0 2.5e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69240.1 - 6.1e-14 51.9 0.1 1.8e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69240.1 - 0.0011 19.2 0.1 0.0034 17.5 0.1 1.9 1 1 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG69244.1 - 1.8e-14 53.5 0.0 3.9e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG69244.1 - 1.4e-11 44.4 0.0 2.4e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69244.1 - 6.9e-08 32.7 0.1 1.8e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG69244.1 - 2e-05 24.7 0.0 4.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger PSCyt2 PF07583.11 GBG69244.1 - 0.083 12.8 0.6 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) DPBB_1 PF03330.18 GBG69249.1 - 1.2e-12 47.9 0.0 2.4e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG69249.1 - 1.1e-08 35.0 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen SEC-C PF02810.15 GBG69249.1 - 0.049 13.6 0.6 0.049 13.6 0.6 2.2 2 0 0 2 2 2 0 SEC-C motif Sporozoite_P67 PF05642.11 GBG69251.1 - 0.0052 14.9 0.4 0.0057 14.8 0.4 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen AlaDh_PNT_C PF01262.21 GBG69251.1 - 0.022 14.1 6.1 0.028 13.7 6.1 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Orthopox_C10L PF07020.11 GBG69251.1 - 0.071 13.9 2.7 0.12 13.2 2.7 1.4 1 0 0 1 1 1 0 Orthopoxvirus C10L protein TcdA_TcdB_pore PF12920.7 GBG69251.1 - 0.29 9.3 4.7 0.33 9.2 4.7 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Shadoo PF14999.6 GBG69251.1 - 4.2 7.5 22.5 1.6e+02 2.4 22.5 2.1 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective Phage_holin_3_6 PF07332.11 GBG69251.1 - 8.4 6.5 15.6 13 5.9 15.5 1.4 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF677 PF05055.12 GBG69251.1 - 8.7 5.1 5.6 16 4.3 5.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF677) RasGAP_C PF03836.15 GBG69252.1 - 0.075 13.2 1.6 0.12 12.5 1.6 1.2 1 0 0 1 1 1 0 RasGAP C-terminus DUF1192 PF06698.11 GBG69253.1 - 0.13 12.3 2.3 0.19 11.8 1.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF262 PF03235.14 GBG69254.1 - 0.5 10.5 9.1 2.9 8.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF262 RVT_1 PF00078.27 GBG69255.1 - 4.2e-68 229.2 0.4 7.6e-36 123.7 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69255.1 - 5.3e-30 103.4 0.0 1.2e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69255.1 - 2.9e-29 101.4 0.1 7e-29 100.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69255.1 - 1.8e-18 66.4 1.4 4.5e-18 65.1 1.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69255.1 - 9.3e-09 35.5 0.0 4.8e-06 26.8 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG69255.1 - 5.2e-08 32.7 0.0 9.4e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69255.1 - 2.7e-06 27.9 0.0 6.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69255.1 - 2.5e-05 24.7 0.0 7.3e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG69255.1 - 0.0012 19.0 0.1 0.0037 17.5 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG69255.1 - 0.0045 16.8 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG69255.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease FAM60A PF15396.6 GBG69255.1 - 0.09 12.8 5.2 0.23 11.4 5.2 1.6 1 0 0 1 1 1 0 Protein Family FAM60A DUF1564 PF07600.11 GBG69255.1 - 0.19 11.4 1.3 1.2 8.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) CorA PF01544.18 GBG69255.1 - 0.75 9.1 3.7 2.3 7.5 3.1 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CSRNP_N PF16019.5 GBG69255.1 - 0.98 9.3 4.9 2.5 8.0 4.9 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Arc_PepC_II PF06847.11 GBG69255.1 - 2.6 8.6 4.4 1e+02 3.5 0.0 4.6 4 1 0 4 4 3 0 Archaeal Peptidase A24 C-terminus Type II Asp-B-Hydro_N PF05279.11 GBG69255.1 - 3.8 7.5 17.4 10 6.1 17.4 1.7 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RT_RNaseH_2 PF17919.1 GBG69256.1 - 1.9e-28 98.4 0.0 3.8e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69256.1 - 4.3e-25 88.0 0.0 8e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG69256.1 - 1.4e-08 34.4 1.5 3.2e-08 33.3 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG69256.1 - 4.6e-07 29.6 0.1 7.4e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG69256.1 - 0.00053 19.7 2.0 0.00094 18.9 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Usp PF00582.26 GBG69257.1 - 8.5e-35 120.3 0.1 1.2e-34 119.8 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family CHD5 PF04420.14 GBG69258.1 - 0.53 10.1 2.4 0.91 9.4 2.4 1.3 1 0 0 1 1 1 0 CHD5-like protein RT_RNaseH_2 PF17919.1 GBG69259.1 - 9.4e-27 93.0 0.0 1.9e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69259.1 - 3.1e-25 88.5 0.0 6.3e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69259.1 - 3.6e-18 65.9 0.1 8.5e-12 45.1 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG69259.1 - 3.6e-16 59.0 0.1 1e-15 57.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG69259.1 - 0.0002 21.9 0.0 0.00044 20.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69259.1 - 0.0016 18.9 0.0 0.0034 17.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG69259.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG69259.1 - 0.086 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG69260.1 - 6.2e-29 101.1 0.1 1e-28 100.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 GBG69260.1 - 0.044 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF2722 PF10846.8 GBG69261.1 - 0.046 12.7 13.4 0.084 11.8 13.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.12 GBG69261.1 - 0.061 11.5 36.2 0.084 11.1 36.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG69261.1 - 0.073 12.5 39.0 0.098 12.1 39.0 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG69261.1 - 0.076 12.6 14.7 0.1 12.2 14.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 GBG69261.1 - 0.38 7.8 1.9 0.45 7.6 1.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 GBG69261.1 - 1.1 8.0 14.5 1.5 7.5 14.5 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG69261.1 - 2.6 6.7 10.6 3.7 6.2 10.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 GBG69261.1 - 3.5 6.0 35.8 5.9 5.2 35.8 1.3 1 0 0 1 1 1 0 Mpp10 protein RT_RNaseH PF17917.1 GBG69262.1 - 5.6e-20 71.6 0.0 1.1e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69262.1 - 4.1e-19 68.5 0.0 8.5e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69262.1 - 8e-08 32.1 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG69262.1 - 1.7e-05 25.3 0.0 5e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69262.1 - 0.00048 20.7 0.0 0.0019 18.8 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG69262.1 - 0.005 17.1 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG69262.1 - 0.017 14.9 0.5 0.031 14.1 0.5 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG69263.1 - 2.4e-14 53.5 0.3 6.6e-14 52.0 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG69263.1 - 0.00014 21.5 0.3 0.00028 20.6 0.3 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Utp14 PF04615.13 GBG69264.1 - 2.3 6.7 24.4 2.6 6.5 24.4 1.0 1 0 0 1 1 1 0 Utp14 protein Dapper PF15268.6 GBG69264.1 - 4.9 5.9 17.8 6 5.6 17.8 1.1 1 0 0 1 1 1 0 Dapper RT_RNaseH_2 PF17919.1 GBG69265.1 - 1.1e-25 89.5 0.0 1.9e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69265.1 - 9.9e-24 83.6 0.0 1.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69265.1 - 1.7e-16 60.4 0.0 2.5e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 GBG69265.1 - 0.084 11.6 14.1 0.11 11.2 14.1 1.2 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 GBG69265.1 - 2.9 6.9 18.9 4.5 6.3 18.9 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Glyco_trans_1_4 PF13692.6 GBG69266.1 - 3.4e-05 24.3 0.0 6.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GBG69266.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glycos_transf_4 PF00953.21 GBG69267.1 - 3.8e-31 108.2 10.4 3.8e-31 108.2 10.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 GBG69267.1 - 0.00023 20.5 0.8 0.00023 20.5 0.8 2.4 3 0 0 3 3 3 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Ubie_methyltran PF01209.18 GBG69268.1 - 1.6e-84 282.9 0.0 1.9e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GBG69268.1 - 1.8e-14 54.1 0.0 3.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG69268.1 - 7.2e-14 52.3 0.1 6.1e-13 49.3 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG69268.1 - 1.1e-10 42.1 0.0 1.9e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG69268.1 - 1.3e-10 41.3 0.0 2.8e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG69268.1 - 0.00017 21.5 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GBG69268.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Glyco_hydro_18 PF00704.28 GBG69269.1 - 1.3e-09 38.3 0.0 3.8e-09 36.7 0.0 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 PA26 PF04636.13 GBG69269.1 - 0.18 10.7 9.0 1.2 8.0 10.6 1.5 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) MCR_beta PF02241.18 GBG69269.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain DUF3629 PF12302.8 GBG69269.1 - 8.2 5.8 9.2 14 5.0 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) adh_short PF00106.25 GBG69270.1 - 4.9e-25 88.1 0.0 1.4e-07 31.2 0.0 3.3 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 GBG69270.1 - 1.3e-12 47.8 0.0 0.00015 21.4 0.0 3.2 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG69270.1 - 3.3e-06 27.1 0.0 7.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GBG69270.1 - 0.011 15.3 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RT_RNaseH PF17917.1 GBG69272.1 - 1.1e-24 86.7 0.1 2.4e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase adh_short PF00106.25 GBG69272.1 - 1.7e-19 70.0 0.1 1.9e-06 27.5 0.0 3.4 3 0 0 3 3 3 3 short chain dehydrogenase RT_RNaseH_2 PF17919.1 GBG69272.1 - 7e-18 64.5 0.2 1.9e-14 53.5 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase adh_short_C2 PF13561.6 GBG69272.1 - 3e-08 33.5 0.0 0.0036 16.9 0.0 3.8 4 0 0 4 4 4 3 Enoyl-(Acyl carrier protein) reductase RVT_1 PF00078.27 GBG69272.1 - 7.1e-08 32.2 0.1 1.3e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KR PF08659.10 GBG69272.1 - 0.0091 15.9 0.1 0.023 14.6 0.1 1.7 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GBG69272.1 - 0.044 13.2 0.1 3.9 6.9 0.1 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3439 PF11921.8 GBG69273.1 - 0.063 13.2 10.8 0.1 12.5 10.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PNISR PF15996.5 GBG69273.1 - 0.17 12.1 2.0 0.26 11.5 2.0 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR B277 PF17623.2 GBG69273.1 - 0.82 8.7 4.0 1.1 8.2 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Antimicrobial_6 PF08036.11 GBG69274.1 - 0.18 11.9 2.1 0.7 10.0 0.7 2.4 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide HALZ PF02183.18 GBG69274.1 - 0.42 10.9 6.0 25 5.2 0.7 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Dimer_Tnp_hAT PF05699.14 GBG69275.1 - 2.4e-06 27.2 0.5 3.9e-06 26.6 0.5 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RNB PF00773.19 GBG69278.1 - 1.1e-100 337.2 0.0 1.6e-100 336.6 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GBG69278.1 - 1.2e-18 66.9 0.0 2.9e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Collagen PF01391.18 GBG69278.1 - 5.5e-08 32.5 17.5 5.5e-08 32.5 17.5 3.6 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) Rrp44_CSD1 PF17216.3 GBG69278.1 - 1e-06 28.6 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 GBG69278.1 - 0.0013 19.0 0.0 0.0034 17.7 0.0 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 GBG69278.1 - 0.0082 16.3 0.2 0.16 12.2 0.0 2.8 3 0 0 3 3 3 1 Cold shock domain Ribosomal_L21p PF00829.21 GBG69280.1 - 2.9e-17 62.8 0.2 5.3e-17 61.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein rve PF00665.26 GBG69281.1 - 5.8e-16 58.7 0.0 2.1e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG69281.1 - 4.3e-06 27.2 0.0 1.4e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG69281.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69281.1 - 0.00028 21.5 0.0 0.00095 19.8 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG69281.1 - 0.00087 19.1 0.1 0.006 16.4 0.0 2.3 2 0 0 2 2 2 1 Putative peptidase (DUF1758) DUF4703 PF15775.5 GBG69281.1 - 0.046 13.5 1.6 0.089 12.6 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) zf-CCHC PF00098.23 GBG69283.1 - 0.021 14.9 4.3 0.035 14.2 4.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG69283.1 - 0.098 12.5 0.5 0.3 11.0 0.5 1.8 1 0 0 1 1 1 0 Zinc knuckle EBP50_C PF09007.11 GBG69283.1 - 5.3 8.0 8.6 15 6.6 4.2 2.7 2 0 0 2 2 2 0 EBP50, C-terminal CDC27 PF09507.10 GBG69284.1 - 5.3 6.3 35.9 6 6.1 35.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Fe-ADH_2 PF13685.6 GBG69284.1 - 7.5 6.2 7.7 2.5 7.7 5.4 1.4 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase RVT_1 PF00078.27 GBG69285.1 - 3.6e-32 111.7 0.0 2.3e-29 102.5 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69285.1 - 5.9e-24 84.0 0.0 1.4e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69285.1 - 1.1e-19 70.7 0.0 2.6e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG69285.1 - 9.7e-09 35.1 0.0 2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69285.1 - 3e-08 34.2 0.0 8.1e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69285.1 - 2.1e-06 28.2 0.0 5.5e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG69285.1 - 0.00053 19.9 3.8 0.0012 18.8 3.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG69285.1 - 0.0033 17.2 3.1 0.0084 15.9 3.1 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 GBG69285.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Peptidase_S49_N PF08496.10 GBG69285.1 - 2.3 8.3 8.0 6.4 6.8 8.0 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 GBG69285.1 - 5.1 6.8 8.4 11 5.8 8.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2058 PF09831.9 GBG69285.1 - 7.1 6.8 17.2 48 4.1 16.8 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Peptidase_S64 PF08192.11 GBG69285.1 - 9.2 4.6 5.8 13 4.1 5.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 RVT_1 PF00078.27 GBG69286.1 - 8.9e-27 94.0 0.0 2e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAM-associated PF14303.6 GBG69286.1 - 2.1 9.0 11.2 1.9 9.2 7.5 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain WRNPLPNID PF15017.6 GBG69288.1 - 1.7 9.6 13.6 6.4 7.7 1.7 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box RecQ_Zn_bind PF16124.5 GBG69289.1 - 0.14 12.9 0.1 0.14 12.9 0.1 2.6 2 1 0 2 2 2 0 RecQ zinc-binding baeRF_family10 PF18854.1 GBG69290.1 - 0.34 11.2 5.5 0.58 10.4 5.5 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 DivIC PF04977.15 GBG69292.1 - 0.023 14.5 0.0 0.32 10.8 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 GBG69292.1 - 0.18 12.5 0.1 0.6 10.8 0.1 1.9 1 0 0 1 1 1 0 Initiation control protein YabA Glyco_hydro_1 PF00232.18 GBG69293.1 - 9.3e-115 383.6 0.0 1.9e-114 382.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 GCIP PF13324.6 GBG69294.1 - 3.6e-43 148.1 5.4 9.7e-37 127.0 3.7 6.0 3 1 1 4 4 4 2 Grap2 and cyclin-D-interacting BUD22 PF09073.10 GBG69294.1 - 0.0034 16.8 16.2 0.0034 16.8 16.2 5.1 3 1 1 4 4 4 2 BUD22 Swi3 PF07962.12 GBG69295.1 - 0.0059 16.6 0.1 0.0087 16.0 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DHBP_synthase PF00926.19 GBG69296.1 - 3.3e-83 277.9 0.0 4.6e-83 277.5 0.0 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 GBG69296.1 - 6.5e-68 227.4 0.1 2.2e-67 225.7 0.0 1.8 2 0 0 2 2 2 1 GTP cyclohydrolase II CNDH2_C PF16858.5 GBG69297.1 - 4.1 7.2 51.3 8.3 6.2 51.3 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Dapper PF15268.6 GBG69297.1 - 9.4 4.9 34.6 13 4.5 34.6 1.1 1 0 0 1 1 1 0 Dapper Pkinase_Tyr PF07714.17 GBG69299.1 - 1e-43 149.5 0.0 1.5e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG69299.1 - 3.6e-38 131.4 0.0 2.1e-23 83.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Hemopexin PF00045.19 GBG69299.1 - 4.5e-05 23.3 4.3 0.099 12.6 0.1 3.5 3 0 0 3 3 3 2 Hemopexin ABC1 PF03109.16 GBG69299.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Radial_spoke PF04712.12 GBG69301.1 - 0.066 12.1 3.9 0.074 12.0 3.9 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein Pkinase_Tyr PF07714.17 GBG69302.1 - 1e-45 156.1 0.0 1.4e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG69302.1 - 2.8e-43 148.2 0.0 4e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Malectin_like PF12819.7 GBG69302.1 - 2.4e-16 59.8 0.0 3.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Malectin-like domain Malectin PF11721.8 GBG69302.1 - 1.3e-13 51.4 0.0 1.3e-10 41.6 0.0 2.4 2 0 0 2 2 2 2 Malectin domain LRR_8 PF13855.6 GBG69302.1 - 2e-05 24.2 0.1 6.7e-05 22.6 0.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat APH PF01636.23 GBG69302.1 - 0.0033 17.4 0.1 0.013 15.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family zf-CCHC PF00098.23 GBG69303.1 - 3.7e-07 29.9 1.9 7.2e-07 29.0 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG69303.1 - 0.0099 15.8 0.5 0.03 14.3 0.5 1.8 1 0 0 1 1 1 1 Zinc knuckle DDRGK PF09756.9 GBG69303.1 - 0.25 10.9 14.1 0.51 9.9 14.1 1.5 1 0 0 1 1 1 0 DDRGK domain SOBP PF15279.6 GBG69303.1 - 5.1 7.6 8.6 8 7.0 8.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein GLTSCR1 PF15249.6 GBG69304.1 - 6.5e-22 77.9 0.1 6.5e-22 77.9 0.1 2.6 3 1 0 3 3 3 1 Conserved region of unknown function on GLTSCR protein eIF-6 PF01912.18 GBG69305.1 - 9.1e-70 234.1 0.6 1.3e-69 233.5 0.3 1.3 2 0 0 2 2 2 1 eIF-6 family Nucleotid_trans PF03407.16 GBG69306.1 - 3.5e-48 164.4 0.1 7.6e-48 163.3 0.0 1.5 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase SAPS PF04499.15 GBG69306.1 - 0.27 9.9 6.5 0.38 9.5 6.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 GBG69306.1 - 7.1 4.6 9.0 12 3.8 9.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nucleotid_trans PF03407.16 GBG69307.1 - 2.7e-43 148.4 0.1 3.7e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase FAM76 PF16046.5 GBG69308.1 - 0.016 14.6 5.2 0.018 14.4 5.2 1.1 1 0 0 1 1 1 0 FAM76 protein RibD_C PF01872.17 GBG69308.1 - 0.13 12.1 1.6 0.17 11.7 1.6 1.2 1 0 0 1 1 1 0 RibD C-terminal domain PspB PF06667.12 GBG69308.1 - 4.9 7.3 7.1 32 4.7 0.1 2.6 2 0 0 2 2 2 0 Phage shock protein B Dynamin_N PF00350.23 GBG69310.1 - 1.3e-23 83.9 0.1 4.1e-11 43.2 0.1 2.4 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 GBG69310.1 - 6.6e-13 48.7 0.0 1.6e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GBG69310.1 - 1.2e-05 24.9 0.0 5e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TMP-TENI PF02581.17 GBG69310.1 - 2.2e-05 23.9 0.0 7.5e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 Thiamine monophosphate synthase RsgA_GTPase PF03193.16 GBG69310.1 - 5.3e-05 23.2 0.7 0.091 12.7 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 GBG69310.1 - 0.00049 19.5 0.4 0.01 15.2 0.4 2.3 1 1 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 GBG69310.1 - 0.00064 19.3 0.9 1.8 8.0 0.0 3.2 3 0 0 3 3 3 2 Ferrous iron transport protein B Baculo_PEP_C PF04513.12 GBG69310.1 - 0.069 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.27 GBG69310.1 - 0.075 13.6 0.0 0.22 12.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_15 PF13175.6 GBG69310.1 - 0.13 12.0 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 GBG69310.1 - 0.14 11.7 0.0 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Exonuc_VII_L PF02601.15 GBG69310.1 - 0.24 10.9 3.9 0.64 9.5 3.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4559 PF15112.6 GBG69310.1 - 0.48 10.0 2.6 0.33 10.6 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Snapin_Pallidin PF14712.6 GBG69310.1 - 5.4 7.5 7.0 1.4 9.4 3.2 1.9 2 0 0 2 2 2 0 Snapin/Pallidin RVT_1 PF00078.27 GBG69312.1 - 6.7e-59 199.1 0.6 2.7e-30 105.6 0.1 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG69312.1 - 7.5e-10 38.6 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG69312.1 - 5e-07 29.9 0.0 1.8e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Ribosomal_L34 PF00468.17 GBG69312.1 - 0.0087 16.0 2.5 12 6.0 0.1 3.8 4 0 0 4 4 4 1 Ribosomal protein L34 DUF3368 PF11848.8 GBG69312.1 - 0.071 12.9 0.0 15 5.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Trans_reg_C PF00486.28 GBG69312.1 - 0.15 12.2 1.1 5.3 7.2 0.1 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Dak1 PF02733.17 GBG69313.1 - 4.5e-114 380.5 0.3 5.7e-114 380.2 0.3 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 GBG69313.1 - 1.4e-46 158.6 1.5 2.6e-46 157.7 1.5 1.5 1 0 0 1 1 1 1 DAK2 domain FAD_binding_2 PF00890.24 GBG69314.1 - 1.3e-80 271.5 0.2 1.9e-80 271.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GBG69314.1 - 6.7e-25 87.8 0.2 1.2e-24 87.1 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GBG69314.1 - 1.3e-16 60.8 0.0 2.6e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DAO PF01266.24 GBG69314.1 - 4.7e-11 42.9 6.5 1.9e-07 31.0 2.5 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GBG69314.1 - 1.8e-09 37.6 0.7 1.7e-08 34.6 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GBG69314.1 - 6e-08 32.4 4.9 1.1e-07 31.5 4.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GBG69314.1 - 1.1e-06 28.2 3.0 4.4e-06 26.2 3.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG69314.1 - 6e-06 25.2 1.9 0.00014 20.7 0.7 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 GBG69314.1 - 4e-05 23.0 0.2 5.7e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 GBG69314.1 - 0.00058 19.1 5.0 0.00058 19.1 2.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_6 PF08030.12 GBG69314.1 - 0.00089 19.4 0.1 0.02 15.0 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox PF00070.27 GBG69314.1 - 0.0051 17.3 4.3 0.082 13.5 1.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GBG69314.1 - 0.007 16.4 0.3 0.22 11.5 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GBG69314.1 - 0.033 13.4 1.5 0.077 12.2 0.5 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GBG69314.1 - 0.036 13.3 4.7 0.026 13.8 1.5 2.2 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 GBG69314.1 - 0.041 12.9 1.1 0.064 12.3 1.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 GBG69314.1 - 0.078 12.3 1.6 0.15 11.3 1.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 GBG69314.1 - 0.11 11.7 3.2 0.42 9.8 1.0 2.1 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GBG69315.1 - 1.5e-80 271.3 0.2 2.2e-80 270.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GBG69315.1 - 7.3e-25 87.7 0.2 1.3e-24 86.9 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GBG69315.1 - 1.4e-16 60.7 0.0 2.8e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DAO PF01266.24 GBG69315.1 - 6.4e-11 42.4 6.7 2.3e-07 30.8 2.7 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GBG69315.1 - 2e-09 37.5 0.7 1.8e-08 34.5 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GBG69315.1 - 9e-08 31.9 5.4 1.7e-07 30.9 5.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GBG69315.1 - 1.2e-06 27.9 3.0 4.9e-06 26.0 3.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG69315.1 - 6.9e-06 25.0 1.9 0.00015 20.6 0.7 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 GBG69315.1 - 4.3e-05 22.9 0.2 6.2e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 GBG69315.1 - 0.00062 19.0 2.1 0.00062 19.0 2.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_6 PF08030.12 GBG69315.1 - 0.001 19.2 0.1 0.022 14.9 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox PF00070.27 GBG69315.1 - 0.0056 17.2 4.3 0.088 13.4 1.4 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GBG69315.1 - 0.0081 16.2 0.3 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 GBG69315.1 - 0.034 13.4 4.7 0.028 13.7 1.5 2.3 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 GBG69315.1 - 0.039 13.2 1.6 0.081 12.2 0.5 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GBG69315.1 - 0.044 12.8 1.1 0.068 12.2 1.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 GBG69315.1 - 0.098 11.9 1.8 0.19 11.0 1.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 GBG69315.1 - 0.12 11.6 3.2 0.45 9.7 1.0 2.2 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GBG69316.1 - 1.4e-80 271.4 0.2 2.1e-80 270.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GBG69316.1 - 7e-25 87.8 0.2 1.2e-24 87.0 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GBG69316.1 - 1.3e-16 60.7 0.0 2.7e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DAO PF01266.24 GBG69316.1 - 5.4e-11 42.7 6.5 2e-07 30.9 2.5 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GBG69316.1 - 2e-09 37.6 0.7 1.7e-08 34.5 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GBG69316.1 - 9.2e-08 31.8 5.5 1.7e-07 30.9 5.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GBG69316.1 - 1.2e-06 28.0 3.0 4.7e-06 26.1 3.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG69316.1 - 6.4e-06 25.1 1.9 0.00014 20.7 0.7 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 GBG69316.1 - 4.1e-05 23.0 0.2 6e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 GBG69316.1 - 0.0006 19.0 2.1 0.0006 19.0 2.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_6 PF08030.12 GBG69316.1 - 0.00095 19.3 0.1 0.021 14.9 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox PF00070.27 GBG69316.1 - 0.0055 17.2 4.3 0.085 13.4 1.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GBG69316.1 - 0.0076 16.3 0.3 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 GBG69316.1 - 0.039 13.2 4.7 0.027 13.7 1.5 2.1 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 GBG69316.1 - 0.04 13.2 0.9 0.077 12.3 0.9 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 GBG69316.1 - 0.042 12.9 1.1 0.066 12.2 1.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GBG69316.1 - 0.057 12.7 2.0 0.1 11.9 0.7 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GBG69316.1 - 0.12 11.6 3.2 0.44 9.8 1.0 2.1 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase BTK PF00779.19 GBG69317.1 - 0.05 13.4 0.5 0.05 13.4 0.5 2.0 2 0 0 2 2 2 0 BTK motif CHORD PF04968.12 GBG69317.1 - 0.47 11.2 6.9 0.95 10.2 0.9 2.7 3 0 0 3 3 3 0 CHORD MIF4G_like PF09088.11 GBG69318.1 - 6.9e-39 133.6 0.6 1.2e-37 129.5 0.5 2.3 1 1 1 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 GBG69318.1 - 1.2e-29 103.7 17.8 1.8e-28 99.8 14.1 2.6 1 1 0 1 1 1 1 MIF4G like MIF4G PF02854.19 GBG69318.1 - 1.9e-21 76.7 0.0 3.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain NAM-associated PF14303.6 GBG69318.1 - 0.015 16.0 4.6 0.015 16.0 4.6 2.5 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain Herpes_UL6 PF01763.16 GBG69318.1 - 0.13 10.8 1.4 0.2 10.2 1.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like CRS1_YhbY PF01985.21 GBG69319.1 - 2.2e-30 104.6 0.8 3.1e-19 68.9 0.0 2.3 2 0 0 2 2 2 2 CRS1 / YhbY (CRM) domain DUF155 PF02582.14 GBG69320.1 - 4e-16 59.6 0.4 3.1e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised ACR, YagE family COG1723 SPX PF03105.19 GBG69320.1 - 0.99 9.3 9.9 0.87 9.4 8.4 1.8 2 0 0 2 2 2 0 SPX domain DUF155 PF02582.14 GBG69321.1 - 1.8e-21 77.1 0.0 2.4e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SPX PF03105.19 GBG69321.1 - 1.2 9.0 10.2 0.84 9.5 8.5 1.8 2 0 0 2 2 2 0 SPX domain Ish1 PF10281.9 GBG69322.1 - 0.041 14.2 0.5 0.31 11.4 0.0 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DUF287 PF03384.14 GBG69322.1 - 0.083 13.3 0.6 0.21 12.0 0.6 1.7 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 Borrelia_P13 PF05628.12 GBG69322.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Borrelia membrane protein P13 zf-RanBP PF00641.18 GBG69323.1 - 3.2e-06 26.3 5.1 5.1e-06 25.7 1.2 2.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others PriA_CRR PF18319.1 GBG69323.1 - 0.17 11.9 5.8 9.2 6.4 0.1 2.8 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain DDE_Tnp_4 PF13359.6 GBG69324.1 - 1e-08 35.0 0.0 2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69324.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein DUF2457 PF10446.9 GBG69324.1 - 0.32 10.1 28.5 0.47 9.5 28.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Utp14 PF04615.13 GBG69324.1 - 1.9 7.0 13.3 2.6 6.5 13.3 1.1 1 0 0 1 1 1 0 Utp14 protein SDA1 PF05285.12 GBG69324.1 - 3.2 7.1 22.8 4.6 6.6 22.8 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG69324.1 - 7.9 5.7 20.0 11 5.2 20.0 1.1 1 0 0 1 1 1 0 BUD22 Myb_DNA-bind_4 PF13837.6 GBG69325.1 - 2.5e-09 37.4 4.9 2.5e-09 37.4 4.9 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG69325.1 - 0.00065 19.7 1.5 0.0021 18.1 1.5 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG69325.1 - 0.00073 19.7 2.1 0.0014 18.9 2.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG69325.1 - 0.0022 18.2 3.2 0.0022 18.2 3.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like NAM-associated PF14303.6 GBG69325.1 - 0.52 11.0 11.1 1.3 9.7 1.6 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain PMM PF03332.13 GBG69326.1 - 6.5e-101 336.7 0.1 8.6e-101 336.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 GBG69326.1 - 0.0018 18.0 0.0 0.0081 15.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase FoP_duplication PF13865.6 GBG69326.1 - 0.026 15.1 7.1 0.05 14.2 7.1 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SDA1 PF05285.12 GBG69327.1 - 4.2 6.7 6.3 6.7 6.0 6.3 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG69327.1 - 5.4 5.1 6.4 7.4 4.6 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family GTP_EFTU_D3 PF03143.17 GBG69328.1 - 0.18 12.1 1.0 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain Borrelia_P83 PF05262.11 GBG69328.1 - 1.3 7.5 9.4 1.7 7.1 9.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-C4 PF00105.18 GBG69328.1 - 3.6 8.1 5.6 0.74 10.3 1.7 1.9 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) DEAD PF00270.29 GBG69329.1 - 1.2e-50 171.8 0.0 5.4e-49 166.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG69329.1 - 1.8e-30 105.5 0.0 3.8e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WW PF00397.26 GBG69329.1 - 6.5e-09 35.7 3.3 2.2e-08 34.1 3.3 2.0 1 0 0 1 1 1 1 WW domain ResIII PF04851.15 GBG69329.1 - 6.3e-07 29.6 0.0 1.4e-06 28.5 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GBG69329.1 - 0.0036 16.6 0.0 0.0051 16.0 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 GBG69330.1 - 1.3e-50 171.6 0.0 5.8e-49 166.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG69330.1 - 1.9e-30 105.4 0.0 4.1e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WW PF00397.26 GBG69330.1 - 7e-09 35.6 3.3 2.3e-08 34.0 3.3 2.0 1 0 0 1 1 1 1 WW domain ResIII PF04851.15 GBG69330.1 - 6.5e-07 29.5 0.0 1.5e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GBG69330.1 - 0.0038 16.5 0.0 0.0055 15.9 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Herpes_US9 PF06072.11 GBG69331.1 - 0.33 10.8 1.0 0.96 9.4 0.3 1.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 SelK_SelG PF10961.8 GBG69331.1 - 2.5 8.8 9.0 0.58 10.8 4.8 1.9 2 0 0 2 2 2 0 Selenoprotein SelK_SelG RNA_pol_Rpb1_5 PF04998.17 GBG69332.1 - 2.4e-53 181.3 0.0 3.4e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 AAL_decarboxy PF03306.13 GBG69332.1 - 0.02 14.3 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase Nop14 PF04147.12 GBG69332.1 - 0.99 7.5 12.9 1.4 7.0 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpb1_5 PF04998.17 GBG69333.1 - 1.2e-29 103.5 0.1 1.4e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 GBG69333.1 - 2e-13 50.2 0.0 3.8e-13 49.3 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 CobD_Cbib PF03186.13 GBG69334.1 - 2.8 7.1 9.9 17 4.5 9.9 2.0 1 1 0 1 1 1 0 CobD/Cbib protein Polyoma_coat2 PF00761.20 GBG69334.1 - 8.7 6.0 11.8 10 5.8 11.8 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein DUF4328 PF14219.6 GBG69335.1 - 0.39 10.3 5.4 0.057 13.0 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) MrpF_PhaF PF04066.13 GBG69335.1 - 0.65 10.4 5.2 1.3 9.5 5.2 1.5 1 0 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) PAPS_reduct PF01507.19 GBG69336.1 - 0.047 13.7 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family PGA2 PF07543.12 GBG69336.1 - 2.1 8.3 17.0 2.9 7.9 17.0 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 MCM_bind PF09739.9 GBG69336.1 - 5.7 5.3 5.1 6.3 5.1 5.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Nucleo_P87 PF07267.11 GBG69336.1 - 7.2 5.3 12.1 9.2 5.0 12.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAPS_reduct PF01507.19 GBG69337.1 - 8.2e-05 22.7 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family IFR3_antag PF14754.6 GBG69337.1 - 0.041 13.1 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Papain-like auto-proteinase NAD_synthase PF02540.17 GBG69337.1 - 0.15 11.1 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 NAD synthase ATP_bind_3 PF01171.20 GBG69337.1 - 0.18 11.5 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 PP-loop family rve PF00665.26 GBG69338.1 - 4.7e-16 59.1 0.0 1.1e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG69338.1 - 3.6e-15 56.2 0.1 7.9e-14 51.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69338.1 - 1.7e-11 44.0 0.1 1.6e-10 40.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69338.1 - 8.6e-07 28.7 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG69338.1 - 0.0019 18.7 0.0 0.0052 17.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69338.1 - 0.0035 18.0 0.0 0.0082 16.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG69338.1 - 0.054 13.3 0.5 0.12 12.1 0.5 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-NOSIP PF15906.5 GBG69339.1 - 2.8e-13 49.8 2.6 2.8e-13 49.8 2.6 2.2 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 GBG69339.1 - 1.3e-07 31.2 10.7 1.7e-05 24.3 2.3 2.2 2 0 0 2 2 2 2 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 GBG69339.1 - 0.00028 20.7 32.5 0.011 15.6 12.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG69339.1 - 0.00032 20.6 11.1 0.00032 20.6 11.1 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG69339.1 - 0.0057 16.7 26.2 0.22 11.5 8.1 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 GBG69339.1 - 0.0094 16.3 31.6 0.055 13.8 11.4 2.6 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 GBG69339.1 - 0.11 12.3 31.1 0.13 12.2 11.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GBG69339.1 - 0.14 12.1 23.5 0.38 10.6 6.3 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 GBG69339.1 - 0.36 10.7 35.0 0.32 10.9 14.2 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG69339.1 - 2.5 8.3 30.5 7.5 6.8 11.2 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING HisKA PF00512.25 GBG69340.1 - 3.5e-17 62.2 0.1 8e-17 61.0 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 GBG69340.1 - 4.1e-06 26.9 0.0 0.0016 18.6 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 GBG69340.1 - 0.0022 18.5 0.0 0.0046 17.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UL42 PF17638.2 GBG69340.1 - 0.24 11.4 0.6 0.54 10.2 0.6 1.5 1 0 0 1 1 1 0 HCMV UL42 zf-CCHC PF00098.23 GBG69342.1 - 0.0014 18.6 0.8 0.0053 16.8 0.8 2.1 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG69343.1 - 4.3e-08 33.0 0.0 9.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69343.1 - 3.7e-05 24.3 0.0 0.00016 22.2 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69343.1 - 8.9e-05 23.0 0.0 0.00042 20.8 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG69343.1 - 0.0017 18.3 0.8 0.006 16.6 0.8 2.0 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 GBG69343.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG69343.1 - 0.15 12.4 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease SlyX PF04102.12 GBG69343.1 - 2.6 8.7 6.8 0.72 10.5 0.8 2.7 1 1 1 2 2 2 0 SlyX zf-CCHC PF00098.23 GBG69344.1 - 0.00077 19.4 0.8 0.0016 18.4 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle FAM76 PF16046.5 GBG69346.1 - 0.049 13.0 7.7 0.061 12.7 7.7 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4666 PF15697.5 GBG69346.1 - 0.2 12.4 5.3 0.12 13.1 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) DUF3573 PF12097.8 GBG69346.1 - 0.26 10.1 0.3 0.37 9.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DivIC PF04977.15 GBG69346.1 - 1.3 8.8 16.3 2 8.2 5.3 3.3 3 0 0 3 3 3 0 Septum formation initiator PRTP PF01366.18 GBG69346.1 - 3.9 5.4 8.4 0.51 8.3 4.7 1.4 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Atg14 PF10186.9 GBG69346.1 - 4.2 6.4 11.6 2.4 7.2 0.5 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC1 PF03109.16 GBG69347.1 - 2.8e-39 134.0 2.2 2.1e-37 127.9 0.1 2.3 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 GBG69347.1 - 0.00028 20.9 0.0 0.0007 19.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family SelB-wing_2 PF09106.11 GBG69347.1 - 0.077 13.2 0.1 2.2 8.5 0.0 3.1 2 1 0 2 2 2 0 Elongation factor SelB, winged helix DUF659 PF04937.15 GBG69348.1 - 1.1e-27 96.7 0.1 1.8e-27 96.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG69348.1 - 1.9e-05 24.4 0.5 3.3e-05 23.6 0.5 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FYVE PF01363.21 GBG69348.1 - 0.058 13.5 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 FYVE zinc finger Nic96 PF04097.14 GBG69349.1 - 9.1e-89 298.6 0.0 8.6e-88 295.4 0.0 2.1 1 1 0 1 1 1 1 Nup93/Nic96 Clathrin PF00637.20 GBG69349.1 - 0.0035 17.2 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_7 PF13176.6 GBG69349.1 - 0.0069 16.3 3.0 0.34 11.0 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG69349.1 - 0.008 15.8 1.9 0.044 13.5 0.4 2.6 2 0 0 2 2 2 1 TPR repeat MIT PF04212.18 GBG69349.1 - 0.0081 16.2 0.4 0.51 10.4 0.1 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 GBG69349.1 - 0.021 14.7 4.5 0.39 10.6 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG69349.1 - 0.061 13.5 11.7 1.4 9.2 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG69349.1 - 0.073 13.4 3.8 4.2 7.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PrmA PF06325.13 GBG69349.1 - 0.84 9.0 3.2 0.3 10.4 0.5 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) TPR_3 PF07720.12 GBG69349.1 - 1.1 9.4 7.8 0.47 10.5 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Integrase_H2C2 PF17921.1 GBG69350.1 - 9.1e-14 51.3 0.3 2e-13 50.2 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69350.1 - 3.8e-11 43.2 0.0 8.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG69350.1 - 3.5e-07 30.7 0.0 6.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69350.1 - 2.9e-05 24.6 0.0 5.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG69350.1 - 0.00028 20.7 1.1 0.00052 19.8 1.1 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG69350.1 - 0.015 15.5 2.7 0.018 15.2 1.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger RVP PF00077.20 GBG69350.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Nucleo_P87 PF07267.11 GBG69350.1 - 1.3 7.8 4.7 1.8 7.4 4.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 GBG69350.1 - 3.3 6.4 3.5 4.8 5.8 3.5 1.2 1 0 0 1 1 1 0 Presenilin ORC6 PF05460.13 GBG69350.1 - 5.1 6.3 8.3 9.6 5.4 8.3 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CENP-N PF05238.13 GBG69350.1 - 7.2 5.8 7.1 13 5.0 7.1 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Glyco_transf_28 PF03033.20 GBG69351.1 - 1.4e-24 86.7 0.0 2.7e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GBG69351.1 - 8.4e-07 28.1 0.0 1.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase RNA_pol_3_Rpc31 PF11705.8 GBG69351.1 - 0.00034 20.9 5.0 0.00034 20.9 5.0 3.3 2 1 0 2 2 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2052 PF09747.9 GBG69351.1 - 0.00088 19.5 31.6 0.024 14.8 5.4 2.4 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Nop53 PF07767.11 GBG69351.1 - 0.0021 17.5 22.6 0.0033 16.9 7.8 2.3 2 0 0 2 2 2 2 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.12 GBG69351.1 - 0.006 16.1 27.8 0.026 14.0 11.2 2.3 2 0 0 2 2 2 2 SDA1 PBP1_TM PF14812.6 GBG69351.1 - 0.0097 16.3 4.3 0.0097 16.3 4.3 3.7 3 1 1 4 4 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 GBG69351.1 - 0.049 13.8 27.1 0.41 10.7 7.0 2.5 2 0 0 2 2 2 0 YL1 nuclear protein DUF913 PF06025.12 GBG69351.1 - 0.12 11.3 5.9 0.023 13.7 0.6 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TERB2 PF15101.6 GBG69351.1 - 0.14 12.2 2.7 0.38 10.8 2.7 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Tim54 PF11711.8 GBG69351.1 - 0.7 8.6 11.7 0.018 13.9 3.4 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SMN PF06003.12 GBG69351.1 - 0.76 9.0 6.6 5.3 6.2 1.5 2.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Spt20 PF12090.8 GBG69351.1 - 0.86 9.2 7.8 2 8.0 7.8 1.5 1 0 0 1 1 1 0 Spt20 family Mpp10 PF04006.12 GBG69351.1 - 1 7.7 32.3 0.33 9.4 16.6 2.2 2 0 0 2 2 2 0 Mpp10 protein SpoIIP PF07454.11 GBG69351.1 - 1.7 8.0 13.9 0.14 11.6 7.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 GBG69351.1 - 3.5 5.8 26.8 0.24 9.6 12.2 2.2 2 0 0 2 2 2 0 CDC45-like protein Spore_coat_CotO PF14153.6 GBG69351.1 - 6.6 6.6 24.6 8.7 6.2 2.6 2.6 2 0 0 2 2 2 0 Spore coat protein CotO RNA_pol_Rpc4 PF05132.14 GBG69351.1 - 7.4 7.0 16.6 0.024 15.1 2.3 2.8 3 0 0 3 3 3 0 RNA polymerase III RPC4 HATPase_c_3 PF13589.6 GBG69352.1 - 4e-13 49.4 0.0 8.8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase gag-asp_proteas PF13975.6 GBG69352.1 - 8.5e-07 29.4 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69352.1 - 0.00047 20.7 0.0 0.001 19.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease HATPase_c PF02518.26 GBG69352.1 - 0.0012 19.3 0.0 0.0037 17.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Asp_protease PF09668.10 GBG69352.1 - 0.023 14.5 0.8 0.048 13.5 0.8 1.4 1 0 0 1 1 1 0 Aspartyl protease Zip PF02535.22 GBG69352.1 - 0.13 11.5 3.6 7.3 5.7 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter RVP PF00077.20 GBG69352.1 - 0.15 12.4 0.0 0.37 11.1 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG69353.1 - 2.4e-20 73.0 0.1 5.5e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG69353.1 - 7.9e-08 32.8 0.0 7.7e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69353.1 - 7.8e-07 29.6 0.0 3.3e-06 27.5 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG69353.1 - 0.00014 21.6 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69353.1 - 0.00019 21.2 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG69353.1 - 0.053 13.8 2.2 0.14 12.5 0.0 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein ZapB PF06005.12 GBG69353.1 - 7.3 7.1 8.6 3 8.4 0.0 3.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF659 PF04937.15 GBG69354.1 - 4.6e-15 55.8 0.0 8.4e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) API5 PF05918.11 GBG69354.1 - 0.0025 16.7 3.3 0.0041 16.0 3.3 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) DUF29 PF01724.16 GBG69354.1 - 0.12 12.6 2.5 0.096 12.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF29 zf-BED PF02892.15 GBG69354.1 - 0.16 12.1 0.1 0.55 10.3 0.1 1.9 1 0 0 1 1 1 0 BED zinc finger RVT_1 PF00078.27 GBG69355.1 - 3.6e-15 56.1 0.0 7.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAF-AH_p_II PF03403.13 GBG69355.1 - 0.061 11.8 0.7 1.5 7.3 0.9 2.4 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II RT_RNaseH_2 PF17919.1 GBG69356.1 - 2.9e-20 72.1 0.0 6.5e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69356.1 - 2.6e-19 69.4 0.0 5.5e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69356.1 - 9.1e-14 51.3 0.3 3.8e-13 49.3 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69356.1 - 3.3e-12 46.7 0.0 7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG69356.1 - 1.7e-06 27.8 0.0 4.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG69356.1 - 0.068 13.4 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Bap31_Bap29_C PF18035.1 GBG69356.1 - 0.18 11.8 0.8 0.4 10.7 0.8 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain zf-CCHC_5 PF14787.6 GBG69356.1 - 0.22 11.3 2.3 0.46 10.2 2.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Mod_r PF07200.13 GBG69356.1 - 0.24 11.5 2.4 0.51 10.4 2.4 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 GBG69356.1 - 0.51 11.0 3.4 1.5 9.5 3.4 1.8 1 0 0 1 1 1 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 GBG69356.1 - 3.1 8.4 7.7 0.79 10.4 3.0 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-CW PF07496.15 GBG69357.1 - 5.6e-13 48.7 2.8 1.3e-12 47.5 2.8 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger Morc6_S5 PF17942.1 GBG69357.1 - 4.8e-08 33.1 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like Asp_protease_2 PF13650.6 GBG69357.1 - 5.4e-05 23.7 0.2 0.00013 22.6 0.2 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69357.1 - 0.0068 16.9 0.2 0.015 15.8 0.2 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG69360.1 - 1.5e-30 106.4 0.0 2e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69360.1 - 5.6e-06 26.3 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Herpes_BLRF2 PF05812.12 GBG69361.1 - 0.029 14.5 0.6 0.06 13.5 0.6 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein AIP3 PF03915.13 GBG69361.1 - 0.19 10.8 0.4 0.28 10.3 0.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 TPR_1 PF00515.28 GBG69362.1 - 1.2e-09 37.5 0.1 0.043 13.7 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG69362.1 - 5.5e-06 26.1 0.1 2.5 8.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG69362.1 - 0.0012 18.9 0.8 0.8 10.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG69362.1 - 0.0085 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 GBG69362.1 - 0.021 15.4 0.3 1.2 10.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GBG69362.1 - 0.084 12.6 0.0 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 GBG69362.1 - 0.09 13.1 0.0 1.7 9.0 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Cpn10 PF00166.21 GBG69363.1 - 5.4e-55 183.4 7.4 8.6e-30 102.7 0.2 2.3 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit ATP12 PF07542.11 GBG69365.1 - 3.3e-29 101.6 0.0 4.8e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein TFIIF_alpha PF05793.12 GBG69366.1 - 0.075 11.6 44.7 0.14 10.7 44.7 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 GBG69366.1 - 2.1 7.6 38.3 3.6 6.8 38.3 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG69366.1 - 3.4 5.8 41.5 4.5 5.4 41.5 1.0 1 0 0 1 1 1 0 Nop14-like family Dynamin_M PF01031.20 GBG69367.1 - 0.11 11.6 0.3 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 Dynamin central region Seryl_tRNA_N PF02403.22 GBG69367.1 - 2.9 8.2 8.3 2 8.7 5.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Dynamin_M PF01031.20 GBG69368.1 - 0.11 11.6 0.3 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 Dynamin central region zf-C4H2 PF10146.9 GBG69368.1 - 0.68 10.2 12.8 0.19 12.0 5.5 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein Seryl_tRNA_N PF02403.22 GBG69368.1 - 2.9 8.2 8.3 2 8.7 5.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RRM_1 PF00076.22 GBG69369.1 - 2.3e-15 56.2 0.0 3.8e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_Gp111 PF07410.11 GBG69370.1 - 0.12 12.9 1.1 0.2 12.2 0.3 1.6 2 0 0 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein DUF3654 PF12376.8 GBG69370.1 - 0.14 12.4 0.2 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) DUF410 PF04190.13 GBG69371.1 - 0.0034 17.2 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) CAT_RBD PF03123.15 GBG69371.1 - 0.17 11.9 0.7 19 5.3 0.1 2.3 1 1 1 2 2 2 0 CAT RNA binding domain RWP-RK PF02042.15 GBG69372.1 - 1.4e-22 79.4 0.1 2.8e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain FAM76 PF16046.5 GBG69373.1 - 0.18 11.1 25.0 0.29 10.4 25.0 1.2 1 0 0 1 1 1 0 FAM76 protein PIP5K PF01504.18 GBG69375.1 - 1.7e-41 142.3 1.9 2.5e-33 115.5 1.9 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 GBG69375.1 - 3.1e-33 115.1 0.3 4.9e-33 114.5 0.3 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 GBG69375.1 - 1.2e-09 38.2 0.1 1.2e-09 38.2 0.1 1.9 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_UBOX PF13445.6 GBG69375.1 - 0.15 12.1 6.6 0.24 11.5 0.5 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 GBG69375.1 - 1.1 9.7 8.0 2.5 8.5 0.4 3.0 2 0 0 2 2 2 0 Ring finger domain zf-AN1 PF01428.16 GBG69375.1 - 8.1 6.7 7.1 17 5.6 5.3 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger UNC-50 PF05216.13 GBG69376.1 - 7.1e-29 101.0 0.1 7.8e-29 100.8 0.1 1.0 1 0 0 1 1 1 1 UNC-50 family Herpes_US9 PF06072.11 GBG69376.1 - 1 9.3 2.9 0.69 9.8 0.9 1.7 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 RT_RNaseH PF17917.1 GBG69377.1 - 1e-20 73.9 0.0 2.1e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69377.1 - 1.5e-19 69.8 0.1 3.3e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG69377.1 - 2e-14 53.4 0.0 4.1e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69377.1 - 6.4e-11 42.2 0.5 2.6e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 GBG69377.1 - 0.031 14.1 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase-like UNC-50 PF05216.13 GBG69378.1 - 9.3e-28 97.3 8.5 1.5e-27 96.6 8.5 1.3 1 0 0 1 1 1 1 UNC-50 family RT_RNaseH_2 PF17919.1 GBG69378.1 - 2.3e-21 75.7 0.0 6.1e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69378.1 - 3.6e-21 75.7 0.0 5.8e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69378.1 - 9.4e-12 45.2 0.0 2.6e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG69378.1 - 7.3e-07 29.7 0.0 2.6e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69378.1 - 1.7e-06 28.5 0.0 5.4e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG69378.1 - 0.00022 21.0 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG69378.1 - 0.00027 20.7 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG69379.1 - 9e-13 48.1 0.1 1.5e-11 44.2 0.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG69379.1 - 2.3e-09 37.4 0.0 4.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain MAGI_u5 PF16666.5 GBG69379.1 - 0.024 14.8 1.6 0.052 13.7 1.6 1.5 1 0 0 1 1 1 0 Unstructured region on MAGI zf-H2C2 PF09337.10 GBG69379.1 - 0.032 14.4 0.0 0.32 11.3 0.0 2.7 4 0 0 4 4 4 0 H2C2 zinc finger Ac81 PF05820.11 GBG69380.1 - 0.67 9.5 4.1 0.78 9.3 4.1 1.1 1 0 0 1 1 1 0 Baculoviridae AC81 Halogen_Hydrol PF10112.9 GBG69380.1 - 1.1 9.2 3.4 1.1 9.3 3.4 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CRAL_TRIO PF00650.20 GBG69381.1 - 1.5e-21 76.7 0.0 2.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GBG69381.1 - 2.2e-05 24.6 0.0 4.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Phage_lysis PF03245.13 GBG69381.1 - 0.047 13.8 0.5 0.41 10.8 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Myb_DNA-bind_4 PF13837.6 GBG69382.1 - 6.3e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG69382.1 - 0.0046 17.0 0.1 0.0083 16.2 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 GBG69382.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Myb_DNA-bind_3 PF12776.7 GBG69382.1 - 0.031 15.3 0.0 0.057 14.4 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG69382.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Clathrin_propel PF01394.20 GBG69384.1 - 1 9.8 6.7 6.8 7.2 0.4 3.3 2 2 1 3 3 3 0 Clathrin propeller repeat FERM_f0 PF16511.5 GBG69384.1 - 2.3 8.6 14.6 13 6.2 0.7 4.5 1 1 4 5 5 5 0 N-terminal or F0 domain of Talin-head FERM Peptidase_C48 PF02902.19 GBG69387.1 - 3.4e-18 66.3 0.3 1e-16 61.4 0.3 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TolA_bind_tri PF16331.5 GBG69388.1 - 0.0053 16.8 3.8 0.0053 16.8 3.8 2.6 3 1 1 4 4 4 1 TolA binding protein trimerisation DUF1664 PF07889.12 GBG69388.1 - 0.12 12.5 3.5 0.15 12.1 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 GBG69388.1 - 1.1 9.7 10.5 0.26 11.7 1.0 2.2 2 0 0 2 2 2 0 Fez1 Retrotrans_gag PF03732.17 GBG69388.1 - 1.6 9.1 5.1 0.56 10.5 0.1 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG69389.1 - 2.3e-20 72.8 0.0 6.6e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69389.1 - 3.7e-20 71.8 0.0 8.5e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase dsrm PF00035.26 GBG69389.1 - 8.1e-12 45.7 0.2 1.5e-11 44.8 0.2 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif RVT_1 PF00078.27 GBG69389.1 - 2e-10 40.6 0.2 6.3e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG69389.1 - 0.075 12.1 0.1 0.29 10.2 0.0 1.9 2 1 0 2 2 2 0 Autophagy protein Apg17 Pyr_redox_2 PF07992.14 GBG69390.1 - 0.0004 19.7 0.0 0.0058 15.9 0.0 2.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase T2SSF PF00482.23 GBG69390.1 - 0.16 11.9 0.0 2.4 8.1 0.0 2.9 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein F DUF732 PF05305.14 GBG69390.1 - 3.2 8.2 4.8 63 4.1 0.3 3.7 1 1 0 3 3 3 0 Protein of unknown function (DUF732) DUF4821 PF16092.5 GBG69392.1 - 1.5e-07 31.3 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4821) DUF4821 PF16092.5 GBG69393.1 - 4.4e-10 39.6 0.0 4.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4821) CASP_C PF08172.12 GBG69394.1 - 0.02 14.3 13.8 0.22 10.8 13.8 2.4 1 1 0 1 1 1 0 CASP C terminal TraT PF05818.12 GBG69394.1 - 0.22 11.2 4.9 0.29 10.8 1.1 2.6 2 1 1 3 3 3 0 Enterobacterial TraT complement resistance protein DUF3347 PF11827.8 GBG69394.1 - 0.25 11.5 20.9 0.046 13.9 15.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3347) Trypan_glycop_C PF10659.9 GBG69394.1 - 8.7 6.8 14.3 13 6.2 13.2 2.0 1 1 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain MlaE PF02405.16 GBG69395.1 - 2e-40 138.8 6.2 2.4e-40 138.5 6.2 1.0 1 0 0 1 1 1 1 Permease MlaE FtsX PF02687.21 GBG69395.1 - 2.9 8.4 12.0 4.7 7.7 5.0 2.2 2 0 0 2 2 2 0 FtsX-like permease family MlaE PF02405.16 GBG69396.1 - 3.1e-24 85.8 3.6 3.1e-24 85.8 3.6 1.6 2 0 0 2 2 2 1 Permease MlaE RT_RNaseH PF17917.1 GBG69397.1 - 6.8e-30 103.5 0.0 1.4e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69397.1 - 1.2e-29 102.2 0.0 3.1e-14 52.8 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69397.1 - 1.8e-28 99.6 0.0 3.1e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG69397.1 - 5.5e-12 45.4 0.0 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG69397.1 - 8e-11 42.2 0.0 3.2e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG69398.1 - 1.5e-62 207.8 0.0 1.1e-30 105.6 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69398.1 - 9.3e-49 164.1 0.0 1e-26 93.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69398.1 - 3.7e-24 85.5 0.1 5.6e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OCRE PF17780.1 GBG69399.1 - 1e-11 44.7 6.6 1e-11 44.7 6.6 3.4 3 0 0 3 3 3 2 OCRE domain G-patch PF01585.23 GBG69399.1 - 1.7e-08 34.2 4.4 1.7e-08 34.2 4.4 3.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 GBG69399.1 - 0.0003 20.8 2.3 0.0003 20.8 2.3 4.8 4 0 0 4 4 4 1 G-patch domain Ldl_recept_a PF00057.18 GBG69400.1 - 1.7e-49 165.7 126.5 2e-07 31.1 7.2 11.4 10 1 0 11 11 11 10 Low-density lipoprotein receptor domain class A DUF3449 PF11931.8 GBG69402.1 - 8.2e-69 231.1 4.3 1e-68 230.8 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 GBG69402.1 - 1.2e-16 60.0 0.5 9.1e-16 57.3 0.2 2.4 2 0 0 2 2 2 1 Telomere stability C-terminal SF3A3 PF16837.5 GBG69402.1 - 4e-07 30.5 0.6 7.9e-07 29.5 0.6 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 PRP9_N PF16958.5 GBG69402.1 - 0.0088 16.1 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor PRP9 N-terminus MLTR_LBD PF17765.1 GBG69402.1 - 0.032 14.4 1.5 6 7.0 0.4 2.3 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain SepRS_C PF18006.1 GBG69402.1 - 0.13 12.4 0.3 1.2 9.3 0.3 2.3 1 1 0 1 1 1 0 O-phosphoseryl-tRNA synthetase C-terminal domain DDE_Tnp_4 PF13359.6 GBG69403.1 - 1.5e-23 83.2 0.0 4.4e-23 81.7 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69403.1 - 3.9e-12 46.2 0.0 6.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG69403.1 - 0.00047 19.9 0.2 0.0085 15.8 0.0 2.5 3 0 0 3 3 3 1 Transposase DDE domain Shisa PF13908.6 GBG69405.1 - 0.12 12.6 0.2 0.41 10.9 0.0 1.8 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator MAP17 PF15807.5 GBG69405.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RT_RNaseH PF17917.1 GBG69406.1 - 1.2e-21 77.0 0.0 1.9e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69406.1 - 2.1e-13 50.1 0.0 3.7e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG69406.1 - 0.079 11.3 9.6 0.11 10.8 9.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG69406.1 - 0.75 9.2 10.9 0.89 8.9 10.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG69406.1 - 1.3 7.1 10.4 1.5 7.0 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_4 PF13837.6 GBG69407.1 - 1.7e-08 34.7 3.3 6.1e-07 29.7 1.4 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG69407.1 - 0.012 15.9 4.1 0.026 14.8 1.2 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3675 PF12428.8 GBG69408.1 - 1.6e-26 93.2 0.5 3.1e-26 92.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3675) RINGv PF12906.7 GBG69408.1 - 2.3e-13 50.0 13.0 3.6e-13 49.4 13.0 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 GBG69408.1 - 0.14 12.5 11.0 0.23 11.8 11.0 1.3 1 0 0 1 1 1 0 Ring finger domain AidB_N PF18158.1 GBG69409.1 - 2.8 7.8 4.9 4.5 7.2 4.9 1.2 1 0 0 1 1 1 0 Adaptive response protein AidB N-terminal domain Glyco_hydro_28 PF00295.17 GBG69410.1 - 1.1e-28 100.3 0.3 1.8e-28 99.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 GBG69410.1 - 0.0019 18.1 0.1 0.12 12.2 0.0 2.7 2 0 0 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.6 GBG69410.1 - 0.075 12.9 1.9 0.29 11.0 1.9 2.0 1 1 0 1 1 1 0 Right handed beta helix region TcdA_TcdB PF12919.7 GBG69411.1 - 0.016 14.5 0.2 0.13 11.6 0.1 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Glyco_hydro_28 PF00295.17 GBG69412.1 - 2.5e-21 76.1 0.2 4.1e-21 75.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 GBG69412.1 - 0.032 14.1 0.4 0.06 13.2 0.4 1.4 1 0 0 1 1 1 0 Right handed beta helix region NOA36 PF06524.12 GBG69413.1 - 0.0012 18.2 5.9 0.085 12.2 0.0 3.2 3 0 0 3 3 3 1 NOA36 protein DNA_pol_lambd_f PF10391.9 GBG69413.1 - 0.11 12.3 0.0 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda ApoO PF09769.9 GBG69413.1 - 1.6 8.7 3.3 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein O PNP_phzG_C PF10590.9 GBG69414.1 - 0.74 9.9 4.0 2.4 8.3 1.1 2.4 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region PNP_phzG_C PF10590.9 GBG69415.1 - 0.75 9.9 4.0 2.4 8.3 1.1 2.4 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Integrase_H2C2 PF17921.1 GBG69416.1 - 1.1e-18 67.1 0.2 2e-18 66.2 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG69416.1 - 3.1e-18 66.0 0.3 7e-18 64.8 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69416.1 - 7.9e-15 55.1 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG69416.1 - 6.2e-11 42.2 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ABC_membrane_2 PF06472.15 GBG69418.1 - 4.5e-35 121.4 4.2 3.6e-32 111.8 0.2 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GBG69418.1 - 1.9e-16 60.8 0.0 1.1e-07 32.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter MMADHC PF10229.9 GBG69418.1 - 4.5e-10 39.7 0.0 1e-06 28.7 0.0 2.5 2 0 0 2 2 2 2 Methylmalonic aciduria and homocystinuria type D protein AAA_16 PF13191.6 GBG69418.1 - 0.00072 20.0 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GBG69418.1 - 0.0031 17.9 0.0 0.007 16.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GBG69418.1 - 0.0039 17.1 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 GBG69418.1 - 0.01 15.5 0.1 0.029 14.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG69418.1 - 0.011 16.1 0.8 0.26 11.6 0.2 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GBG69418.1 - 0.051 13.5 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 GBG69418.1 - 0.099 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GBG69418.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 GBG69418.1 - 0.13 12.8 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain Methyltransf_16 PF10294.9 GBG69419.1 - 6.9e-15 55.2 0.0 1.3e-14 54.3 0.0 1.4 2 0 0 2 2 2 1 Lysine methyltransferase DUF938 PF06080.12 GBG69419.1 - 6.3e-05 22.8 0.0 8.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 GBG69419.1 - 0.00036 20.1 0.0 0.00051 19.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GBG69419.1 - 0.00038 21.1 0.0 0.00073 20.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GBG69419.1 - 0.00062 19.3 0.0 0.00083 18.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 GBG69419.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG69419.1 - 0.004 17.8 0.0 0.0063 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GBG69419.1 - 0.0056 16.4 0.0 0.007 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GBG69419.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GBG69419.1 - 0.085 13.5 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 GBG69419.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Glyco_transf_29 PF00777.18 GBG69420.1 - 2.8e-21 76.1 0.0 4.9e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Chromosome_seg PF13889.6 GBG69421.1 - 7.2e-20 70.9 0.0 2.5e-19 69.2 0.0 1.9 1 1 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 GBG69421.1 - 4.1e-05 24.1 0.7 0.00021 21.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) DUF2282 PF10048.9 GBG69422.1 - 0.014 15.4 0.3 0.036 14.1 0.0 1.9 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2282) Corazonin PF17308.2 GBG69422.1 - 3.9 7.8 24.6 2.6 8.4 8.0 2.2 2 0 0 2 2 2 0 Pro-corazonin Menin PF05053.13 GBG69423.1 - 0.5 8.7 8.8 0.71 8.2 8.8 1.2 1 0 0 1 1 1 0 Menin GYF PF02213.16 GBG69424.1 - 2.6e-23 81.4 10.9 1.7e-11 43.6 4.0 2.4 2 0 0 2 2 2 2 GYF domain GYF_2 PF14237.6 GBG69424.1 - 1.4e-07 31.2 3.0 0.00046 19.9 0.2 2.6 2 0 0 2 2 2 2 GYF domain 2 Cactin_mid PF10312.9 GBG69425.1 - 7.9e-59 198.7 3.9 7.9e-59 198.7 3.9 2.9 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 GBG69425.1 - 9.9e-39 132.1 4.3 1.9e-38 131.2 4.3 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DDHD PF02862.17 GBG69425.1 - 0.13 12.4 6.7 0.92 9.6 0.1 3.2 3 0 0 3 3 3 0 DDHD domain Syntaxin-6_N PF09177.11 GBG69426.1 - 7.8e-14 52.0 3.3 3.1e-13 50.1 0.2 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 GBG69426.1 - 0.00029 20.8 1.8 0.00029 20.8 1.8 1.9 2 0 0 2 2 2 1 SNARE domain MCU PF04678.13 GBG69426.1 - 0.021 14.9 0.3 0.78 9.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter IATP PF04568.12 GBG69426.1 - 0.094 13.1 1.2 0.26 11.8 1.2 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP FoP_duplication PF13865.6 GBG69426.1 - 0.44 11.1 3.7 1.1 9.8 3.7 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ADIP PF11559.8 GBG69427.1 - 1.2e-35 122.9 8.8 1.2e-35 122.9 8.8 4.1 4 0 0 4 4 4 2 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 GBG69427.1 - 3.7 8.0 43.0 1.2 9.5 17.6 2.7 2 1 0 2 2 2 0 Fez1 OmpH PF03938.14 GBG69427.1 - 6.7 7.1 48.2 0.041 14.2 17.7 4.3 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) DUF659 PF04937.15 GBG69428.1 - 1.3e-19 70.6 0.1 2.5e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG69428.1 - 0.011 15.8 0.8 0.028 14.4 0.8 1.8 1 0 0 1 1 1 0 BED zinc finger PyrI_C PF02748.15 GBG69428.1 - 0.045 13.7 0.3 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain SAD_SRA PF02182.17 GBG69429.1 - 4.8e-48 162.8 0.1 8.6e-48 162.0 0.1 1.4 1 0 0 1 1 1 1 SAD/SRA domain zf-RING_UBOX PF13445.6 GBG69429.1 - 6.3e-12 45.3 25.9 1.7e-07 31.1 5.0 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG69429.1 - 1.2e-11 44.2 26.1 1.1e-05 25.1 12.2 3.2 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG69429.1 - 2.6e-10 40.0 24.1 8e-06 25.6 9.1 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG69429.1 - 1.7e-09 37.3 30.0 1.8e-05 24.4 4.1 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG69429.1 - 1.3e-07 31.7 29.4 0.00011 22.3 9.7 3.1 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GBG69429.1 - 2.5e-07 30.9 28.7 0.00051 20.3 13.1 3.1 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 GBG69429.1 - 0.00036 20.4 33.6 0.0015 18.4 5.4 3.0 3 0 0 3 3 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG69429.1 - 0.04 13.8 28.4 0.055 13.3 9.3 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 GBG69429.1 - 0.15 12.2 6.7 4.8 7.4 0.6 3.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-rbx1 PF12678.7 GBG69429.1 - 5.2 7.4 23.4 0.067 13.5 7.6 3.9 3 1 0 3 3 3 0 RING-H2 zinc finger domain THOC7 PF05615.13 GBG69431.1 - 3e-22 79.3 12.5 5.1e-22 78.6 12.5 1.3 1 0 0 1 1 1 1 Tho complex subunit 7 Glyco_hydro_18 PF00704.28 GBG69431.1 - 0.13 12.0 0.2 0.19 11.4 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 TMCO5 PF14992.6 GBG69431.1 - 0.22 11.1 9.6 3.6 7.1 0.3 2.1 1 1 1 2 2 2 0 TMCO5 family TMF_TATA_bd PF12325.8 GBG69431.1 - 2.3 8.5 12.0 4.7 7.5 0.2 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding SpecificRecomb PF10136.9 GBG69431.1 - 3.1 6.0 8.0 11 4.2 4.8 2.2 1 1 1 2 2 2 0 Site-specific recombinase DUF3450 PF11932.8 GBG69431.1 - 4.2 6.6 12.8 5.8 6.2 8.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Peptidase_M41 PF01434.18 GBG69432.1 - 2.5e-70 236.2 0.2 4.1e-70 235.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GBG69432.1 - 1.6e-44 151.5 0.0 3.6e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG69432.1 - 7.4e-17 60.9 0.5 3.5e-16 58.7 0.2 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 GBG69432.1 - 0.00012 22.1 0.1 0.0015 18.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GBG69432.1 - 0.0013 18.8 0.0 0.0045 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 GBG69432.1 - 0.0021 17.3 0.1 0.004 16.4 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 GBG69432.1 - 0.0048 17.2 0.7 0.065 13.5 0.2 3.0 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GBG69432.1 - 0.005 16.6 0.4 0.021 14.6 0.0 2.1 3 0 0 3 3 3 1 IstB-like ATP binding protein RuvB_N PF05496.12 GBG69432.1 - 0.0051 16.6 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain FtsH_ext PF06480.15 GBG69432.1 - 0.0059 16.9 0.0 0.16 12.4 0.0 2.8 3 0 0 3 3 3 1 FtsH Extracellular AAA_16 PF13191.6 GBG69432.1 - 0.0077 16.6 0.5 0.0077 16.6 0.5 3.6 3 1 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 GBG69432.1 - 0.036 13.4 0.3 0.074 12.4 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GBG69432.1 - 0.037 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GBG69432.1 - 0.054 13.7 0.7 0.12 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 GBG69432.1 - 0.17 11.4 0.2 0.47 9.9 0.2 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region SANTA PF09133.10 GBG69433.1 - 0.0044 17.5 0.0 0.0095 16.4 0.0 1.5 1 0 0 1 1 1 1 SANTA (SANT Associated) BRD4_CDT PF17105.5 GBG69433.1 - 0.36 10.5 2.1 1.4 8.5 2.1 2.1 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Glyco_hydro_28 PF00295.17 GBG69434.1 - 2.2e-37 128.9 0.7 2.9e-37 128.5 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 GBG69434.1 - 0.00062 19.7 0.5 1.7 8.4 0.0 3.1 2 1 1 3 3 3 2 Pectate lyase superfamily protein Beta_helix PF13229.6 GBG69434.1 - 0.0064 16.4 2.6 0.024 14.5 2.6 2.0 1 1 0 1 1 1 1 Right handed beta helix region Presenilin PF01080.17 GBG69435.1 - 0.009 14.8 13.4 0.0098 14.7 13.4 1.0 1 0 0 1 1 1 1 Presenilin Apt1 PF10351.9 GBG69435.1 - 2.7 6.7 9.3 3.1 6.5 9.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4366 PF14283.6 GBG69435.1 - 3 7.9 15.7 96 3.0 15.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Raftlin PF15250.6 GBG69435.1 - 4.1 6.0 15.6 4.9 5.8 15.6 1.0 1 0 0 1 1 1 0 Raftlin PI3K_1B_p101 PF10486.9 GBG69435.1 - 9.1 3.9 11.0 13 3.4 11.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Rsd_AlgQ PF04353.13 GBG69437.1 - 0.044 13.7 0.1 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Spc29 PF17082.5 GBG69437.1 - 2 8.2 7.5 0.86 9.4 3.5 2.2 2 1 1 3 3 3 0 Spindle Pole Component 29 RPA_C PF08784.11 GBG69437.1 - 2.2 9.0 0.0 2.2 9.0 0.0 3.7 3 1 0 3 3 3 0 Replication protein A C terminal DnaJ PF00226.31 GBG69439.1 - 9.4e-21 73.7 0.5 2e-20 72.6 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain Rx_N PF18052.1 GBG69439.1 - 0.08 13.2 0.1 0.08 13.2 0.1 2.2 3 0 0 3 3 3 0 Rx N-terminal domain DUF812 PF05667.11 GBG69439.1 - 0.14 11.0 13.9 1 8.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 GBG69439.1 - 0.17 11.2 3.1 9.1 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 GBG69439.1 - 0.6 10.2 19.9 0.12 12.5 8.0 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DinB PF05163.12 GBG69439.1 - 2.3 8.1 5.2 8.3 6.3 1.1 2.4 2 0 0 2 2 2 0 DinB family eIF3_N PF09440.10 GBG69439.1 - 3 8.3 4.8 0.76 10.2 0.6 2.0 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Nop14 PF04147.12 GBG69440.1 - 8.6e-196 652.9 37.0 1.9e-195 651.8 37.0 1.4 1 1 0 1 1 1 1 Nop14-like family Nkap_C PF06047.11 GBG69441.1 - 3.1e-49 165.3 2.9 3.1e-49 165.3 2.9 2.7 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain Kin17_mid PF10357.9 GBG69443.1 - 2.1e-48 163.4 2.0 3.7e-48 162.6 2.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 GBG69443.1 - 0.041 14.3 7.5 0.041 14.3 7.5 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GBG69443.1 - 9.5 6.6 16.2 0.36 11.2 7.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Integrase_H2C2 PF17921.1 GBG69445.1 - 7.1e-12 45.3 1.0 1.4e-11 44.3 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG69445.1 - 3.4e-10 39.8 0.0 6.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69445.1 - 7.4e-07 29.4 0.0 2.1e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG69445.1 - 0.016 15.4 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Pribosyltran_N PF13793.6 GBG69446.1 - 2.9e-18 65.9 0.0 5.8e-17 61.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GBG69446.1 - 3.6e-11 43.4 1.9 3.6e-11 43.4 1.9 1.7 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GBG69446.1 - 1.3e-08 34.5 0.2 2.8e-08 33.4 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Rsa3 PF14615.6 GBG69446.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Ribosome-assembly protein 3 RT_RNaseH PF17917.1 GBG69447.1 - 4.6e-16 59.0 0.0 1e-14 54.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69447.1 - 1.5e-14 53.9 1.6 1.9e-14 53.5 0.4 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG69447.1 - 3.1e-11 43.2 0.0 1.3e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG69447.1 - 1.9e-09 37.9 0.1 7e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69447.1 - 7e-05 23.4 0.0 0.00018 22.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG69447.1 - 0.0015 18.3 1.1 0.0029 17.4 1.1 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG69447.1 - 0.0017 18.5 0.0 0.0054 16.9 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVP PF00077.20 GBG69447.1 - 0.043 14.1 0.0 0.17 12.2 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG69448.1 - 7.6e-05 23.2 0.0 0.00029 21.3 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69448.1 - 0.0052 17.4 0.0 0.02 15.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG69448.1 - 0.006 16.8 4.0 0.019 15.2 4.0 1.8 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 RVP PF00077.20 GBG69448.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG69448.1 - 0.23 11.3 1.3 0.44 10.4 1.3 1.4 1 0 0 1 1 1 0 Aspartyl protease TPR_MLP1_2 PF07926.12 GBG69448.1 - 4.5 7.4 10.1 1.5 8.9 6.3 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RT_RNaseH PF17917.1 GBG69449.1 - 7.6e-19 67.9 0.0 1.5e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69449.1 - 2.4e-18 66.0 0.0 5.5e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69449.1 - 0.00052 19.6 0.0 0.00083 18.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG69449.1 - 0.0082 16.7 0.8 0.033 14.8 0.1 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69449.1 - 0.019 15.6 0.1 0.068 13.8 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 GBG69449.1 - 0.13 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 GBG69449.1 - 0.16 12.1 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain Nop14 PF04147.12 GBG69450.1 - 0.0014 16.9 7.7 0.0016 16.8 7.7 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG69450.1 - 0.092 12.2 12.2 0.11 11.8 12.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG69450.1 - 0.22 9.8 11.5 0.27 9.5 11.5 1.0 1 0 0 1 1 1 0 CDC45-like protein SIR4_SID PF16991.5 GBG69450.1 - 3.5 7.7 7.0 5.2 7.1 7.0 1.2 1 0 0 1 1 1 0 Sir4 SID domain RT_RNaseH_2 PF17919.1 GBG69451.1 - 1.8e-25 88.9 0.0 3.3e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69451.1 - 5.7e-23 81.2 0.0 1.4e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69451.1 - 5.3e-10 39.2 0.2 7.9e-10 38.6 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG69451.1 - 1.3 7.3 5.3 1.7 6.9 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG69451.1 - 2.2 7.6 9.1 3.1 7.0 9.1 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GBG69452.1 - 0.23 9.6 6.4 0.25 9.5 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG69452.1 - 0.33 10.3 7.8 0.42 10.0 7.8 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG69452.1 - 1.1 7.4 5.8 1.3 7.2 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG69452.1 - 8.2 5.7 9.1 11 5.2 9.1 1.2 1 0 0 1 1 1 0 NOA36 protein RT_RNaseH_2 PF17919.1 GBG69453.1 - 1.7e-21 76.1 0.0 4.6e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69453.1 - 2.3e-20 72.8 0.0 5e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Imm71 PF15602.6 GBG69453.1 - 0.014 15.5 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 71 RVT_1 PF00078.27 GBG69454.1 - 5.1e-29 101.4 0.0 8.8e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69454.1 - 4.7e-13 49.0 0.0 1.4e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG69454.1 - 5.4e-05 23.4 2.7 0.002 18.4 0.0 4.2 4 0 0 4 4 4 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG69454.1 - 0.00026 21.3 0.0 0.00072 19.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG69459.1 - 4.6e-25 88.1 0.0 7.8e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69459.1 - 1.1e-07 31.6 0.0 2.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Nucleolin_bd PF16725.5 GBG69459.1 - 0.13 12.0 0.0 7.3 6.3 0.0 2.8 2 0 0 2 2 2 0 Nucleolin binding domain AsmA PF05170.14 GBG69460.1 - 0.15 10.9 0.0 2.9 6.6 0.0 2.0 2 0 0 2 2 2 0 AsmA family Antimicrobial19 PF08225.11 GBG69460.1 - 0.15 11.7 0.2 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Gln-synt_C PF00120.24 GBG69465.1 - 3.7e-15 55.8 0.0 2.4e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG69465.1 - 4.6e-11 42.3 0.0 8.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 GBG69466.1 - 1e-13 51.0 0.0 2.1e-12 46.7 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG69466.1 - 0.00093 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Glycolytic PF00274.19 GBG69467.1 - 3e-167 555.7 0.1 4e-167 555.3 0.1 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Dimer_Tnp_hAT PF05699.14 GBG69467.1 - 0.0002 21.1 0.1 0.00045 19.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CDC45 PF02724.14 GBG69468.1 - 0.062 11.6 14.2 0.082 11.2 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG69468.1 - 0.1 12.0 20.9 0.14 11.6 20.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5584 PF17822.1 GBG69468.1 - 0.2 11.1 0.7 7.2 6.0 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5584) Afi1 PF07792.12 GBG69468.1 - 0.75 10.3 7.6 1.2 9.6 7.6 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SAPS PF04499.15 GBG69468.1 - 0.77 8.5 4.5 1.1 7.9 4.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GBG69468.1 - 1.2 7.9 8.3 1.6 7.4 8.3 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG69468.1 - 1.5 7.0 21.9 1.9 6.6 21.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG69468.1 - 1.8 7.9 20.6 2.2 7.5 20.6 1.1 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.8 GBG69468.1 - 2.3 7.1 8.8 3.2 6.6 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) V_ATPase_I PF01496.19 GBG69468.1 - 2.4 6.0 6.0 3.3 5.5 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2457 PF10446.9 GBG69468.1 - 5.5 6.0 25.0 7.7 5.5 25.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GIY-YIG PF01541.24 GBG69472.1 - 0.0048 17.1 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG69473.1 - 0.0025 17.8 4.2 0.0025 17.8 4.2 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG69473.1 - 0.075 12.9 9.6 0.018 14.8 5.9 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG69474.1 - 0.0019 18.2 4.2 0.0019 18.2 4.2 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG69474.1 - 0.014 15.2 5.9 0.014 15.2 5.9 1.9 2 0 0 2 2 2 0 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG69475.1 - 7.3e-29 100.5 0.0 1.6e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69475.1 - 3.9e-10 39.7 0.0 9e-10 38.5 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG69475.1 - 0.0019 17.9 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG69477.1 - 4.5e-16 58.9 0.0 1.1e-15 57.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69477.1 - 5.6e-06 26.1 0.0 8.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein RVT_1 PF00078.27 GBG69478.1 - 1.8e-25 89.7 1.0 4.9e-25 88.3 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69478.1 - 6.8e-22 77.4 0.0 1.3e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69478.1 - 3.1e-21 75.6 0.0 5.7e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69478.1 - 9.4e-11 41.7 0.1 2.7e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69478.1 - 3.3e-07 30.5 0.0 1.5e-06 28.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Myb_DNA-bind_4 PF13837.6 GBG69479.1 - 1.2e-05 25.6 0.5 2.7e-05 24.5 0.5 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG69479.1 - 0.037 14.1 1.0 0.078 13.1 1.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2057 PF09829.9 GBG69479.1 - 0.076 13.2 1.1 0.14 12.3 1.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Topo_Zn_Ribbon PF08272.11 GBG69481.1 - 0.009 15.7 0.3 0.016 14.8 0.3 1.4 1 0 0 1 1 1 1 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG69481.1 - 0.3 11.3 2.1 0.54 10.4 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Chlam_PMP PF02415.17 GBG69482.1 - 1e-05 25.7 32.7 0.027 15.0 3.1 7.0 7 0 0 7 7 7 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Neocarzinostat PF00960.18 GBG69482.1 - 0.003 17.5 2.5 0.003 17.5 2.5 2.2 2 0 0 2 2 2 1 Neocarzinostatin family DUF5123 PF17161.4 GBG69482.1 - 0.18 12.9 5.1 0.77 10.8 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5123) Chlam_PMP PF02415.17 GBG69483.1 - 1.5e-10 40.9 31.3 0.44 11.1 0.7 8.1 7 0 0 7 7 7 6 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Neocarzinostat PF00960.18 GBG69483.1 - 0.029 14.4 0.2 0.14 12.2 0.2 2.2 1 0 0 1 1 1 0 Neocarzinostatin family Myb_DNA-bind_4 PF13837.6 GBG69484.1 - 0.0027 18.0 0.1 0.0047 17.3 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG69484.1 - 0.0069 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG69484.1 - 0.03 14.5 0.1 0.073 13.3 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Beta_helix PF13229.6 GBG69485.1 - 1.9e-08 34.3 21.9 5.5e-07 29.6 7.1 2.2 1 1 1 2 2 2 2 Right handed beta helix region Neocarzinostat PF00960.18 GBG69485.1 - 0.00066 19.6 0.8 0.0019 18.1 0.8 1.9 1 1 0 1 1 1 1 Neocarzinostatin family Chlam_PMP PF02415.17 GBG69485.1 - 0.00084 19.7 29.6 0.57 10.8 1.4 6.8 7 0 0 7 7 7 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat CSN8_PSD8_EIF3K PF10075.9 GBG69486.1 - 4.1e-19 69.0 0.0 5.7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family ATG16 PF08614.11 GBG69487.1 - 0.0062 16.8 12.8 0.0062 16.8 12.8 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 GBG69487.1 - 0.022 15.0 5.3 0.022 15.0 5.3 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 GBG69487.1 - 0.065 13.3 33.3 0.36 10.9 17.6 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HIP1_clath_bdg PF16515.5 GBG69487.1 - 0.096 13.3 34.1 0.19 12.3 2.3 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BTAD PF03704.17 GBG69487.1 - 0.26 11.7 22.7 0.11 13.0 2.1 3.2 1 1 2 3 3 3 0 Bacterial transcriptional activator domain BRE1 PF08647.11 GBG69487.1 - 0.32 11.1 22.4 0.068 13.3 11.3 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Vps53_N PF04100.12 GBG69487.1 - 0.48 9.3 8.6 0.61 9.0 8.6 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal MAD PF05557.13 GBG69487.1 - 0.6 8.4 23.9 0.86 7.9 23.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF1192 PF06698.11 GBG69487.1 - 0.7 10.0 7.0 2.5 8.2 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Fungal_TACC PF12709.7 GBG69487.1 - 1.1 9.7 14.3 0.78 10.2 0.2 4.1 2 2 3 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 GBG69487.1 - 1.2 7.9 27.3 0.9 8.4 10.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 GBG69487.1 - 1.4 8.7 13.3 3.9 7.3 5.9 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4407 PF14362.6 GBG69487.1 - 1.6 8.0 23.9 11 5.3 23.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 GBG69487.1 - 1.8 9.0 25.9 1 9.8 15.0 2.1 1 1 1 2 2 2 0 Fez1 DUF4665 PF15679.5 GBG69487.1 - 3 8.5 5.4 1.7 9.3 2.7 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4665) Leu_zip PF15294.6 GBG69487.1 - 3.1 7.2 22.3 1.7 8.1 11.4 2.1 1 1 1 2 2 2 0 Leucine zipper PRKG1_interact PF15898.5 GBG69487.1 - 3.7 8.5 24.9 0.58 11.1 7.8 3.4 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain MHB PF16525.5 GBG69487.1 - 5.7 7.3 8.0 6.8 7.0 0.2 3.0 2 1 1 3 3 3 0 Haemophore, haem-binding YscO PF07321.12 GBG69487.1 - 5.9 6.8 32.5 4.5 7.2 6.8 2.6 1 1 1 2 2 2 0 Type III secretion protein YscO OmpH PF03938.14 GBG69487.1 - 6 7.2 34.7 0.21 11.9 2.9 3.1 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 GBG69487.1 - 7.9 6.5 15.7 0.37 10.8 6.5 2.4 1 1 1 2 2 2 0 Laminin Domain II NBP1 PF08537.10 GBG69487.1 - 8.6 5.7 10.9 12 5.2 10.9 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 TBCA PF02970.16 GBG69487.1 - 9.4 6.7 17.2 0.35 11.2 3.9 2.8 1 1 2 3 3 3 0 Tubulin binding cofactor A RNase_PH PF01138.21 GBG69488.1 - 8.5e-26 91.0 0.0 3.2e-25 89.1 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GBG69488.1 - 1.8e-05 24.7 0.0 7.6e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 GBG69489.1 - 7.8e-26 91.1 0.0 2.8e-25 89.4 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GBG69489.1 - 3.5e-07 30.2 0.0 1.6e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Integrase_H2C2 PF17921.1 GBG69491.1 - 1.7e-19 69.6 1.2 4e-19 68.5 1.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG69491.1 - 1.5e-18 67.0 0.0 5.8e-18 65.1 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69491.1 - 1e-17 64.0 0.0 2.4e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69491.1 - 2e-16 60.2 0.0 5.4e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG69491.1 - 7.9e-10 38.6 0.0 1.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG69491.1 - 0.095 12.9 0.3 0.2 11.9 0.3 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Chlam_PMP PF02415.17 GBG69492.1 - 4.6e-09 36.2 26.8 0.27 11.8 1.4 7.5 7 1 0 7 7 7 6 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Neocarzinostat PF00960.18 GBG69492.1 - 0.028 14.4 0.2 0.082 12.9 0.2 1.8 1 1 0 1 1 1 0 Neocarzinostatin family Myb_DNA-bind_4 PF13837.6 GBG69493.1 - 5.7e-06 26.6 4.6 1.2e-05 25.6 4.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG69493.1 - 0.029 14.7 3.8 0.086 13.2 2.0 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ras PF00071.22 GBG69494.1 - 4.1e-56 189.1 0.2 4.8e-56 188.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG69494.1 - 3.3e-33 114.5 0.1 5.5e-33 113.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG69494.1 - 6.6e-13 48.5 0.0 7.8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GBG69494.1 - 9.7e-08 32.1 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GBG69494.1 - 2.4e-06 27.1 0.1 2.9e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GBG69494.1 - 3e-05 23.6 0.2 0.00096 18.7 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GBG69494.1 - 0.00076 19.4 0.1 0.0029 17.5 0.1 1.9 1 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 GBG69494.1 - 0.00087 18.9 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 GBG69494.1 - 0.0029 16.9 0.3 0.011 15.1 0.1 1.8 2 0 0 2 2 2 1 Septin SRPRB PF09439.10 GBG69494.1 - 0.0063 16.0 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 GBG69494.1 - 0.0099 15.7 0.6 0.27 11.0 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 GBG69494.1 - 0.011 15.3 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GBG69494.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.9 GBG69494.1 - 0.011 15.5 0.1 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 GBG69494.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GBG69494.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GBG69494.1 - 0.018 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GBG69494.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 GBG69494.1 - 0.057 12.8 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NB-ARC PF00931.22 GBG69494.1 - 0.06 12.5 0.4 0.09 12.0 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain MCM PF00493.23 GBG69494.1 - 0.062 12.4 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 GBG69494.1 - 0.092 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 GBG69494.1 - 0.099 11.8 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 G-alpha PF00503.20 GBG69494.1 - 0.1 11.8 1.7 0.49 9.5 0.1 2.4 1 1 1 3 3 3 0 G-protein alpha subunit AAA_5 PF07728.14 GBG69494.1 - 0.18 11.8 0.0 0.42 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD_2 PF06733.15 GBG69495.1 - 8.2e-51 172.1 0.0 1.3e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 GBG69495.1 - 1.8e-49 168.2 0.0 4.5e-49 166.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 GBG69495.1 - 0.00046 20.2 0.2 0.59 10.1 0.0 2.6 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG69495.1 - 0.021 14.6 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase SNF2_N PF00176.23 GBG69495.1 - 0.13 11.0 0.0 1.2 7.8 0.0 2.0 2 0 0 2 2 2 0 SNF2 family N-terminal domain PhoH PF02562.16 GBG69495.1 - 0.2 11.1 0.0 18 4.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Beta-lactamase PF00144.24 GBG69496.1 - 6.3e-52 176.8 2.6 3.6e-46 157.9 0.1 3.4 3 0 0 3 3 3 3 Beta-lactamase ABC1 PF03109.16 GBG69496.1 - 1.8e-30 105.5 0.1 4.1e-30 104.4 0.1 1.6 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.11 GBG69496.1 - 0.24 11.0 0.0 0.4 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Nop14 PF04147.12 GBG69497.1 - 0.36 9.0 32.1 0.48 8.6 32.1 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG69497.1 - 2.6 6.6 40.6 2.8 6.4 40.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FCSD-flav_bind PF09242.11 GBG69498.1 - 0.21 12.0 6.2 1.6 9.1 0.1 3.5 3 1 1 4 4 4 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding zf-TRAF PF02176.18 GBG69499.1 - 7.1e-10 39.4 24.1 6.6e-08 33.1 7.8 3.4 2 1 1 3 3 3 2 TRAF-type zinc finger zf-C3HC4_4 PF15227.6 GBG69499.1 - 2.7e-06 27.4 8.2 2.7e-06 27.4 8.2 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.5 GBG69499.1 - 3.5e-06 27.4 21.2 6.8e-06 26.5 6.7 3.4 1 1 2 3 3 3 2 TRAF-like zinc-finger zf-C3HC4 PF00097.25 GBG69499.1 - 4e-05 23.4 8.1 4e-05 23.4 8.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG69499.1 - 0.001 18.8 8.3 0.001 18.8 8.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG69499.1 - 0.0024 17.7 9.7 0.0024 17.7 9.7 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG69499.1 - 0.0027 17.7 10.6 0.01 15.8 10.6 2.1 1 0 0 1 1 1 1 RING-type zinc-finger Sina PF03145.16 GBG69499.1 - 0.0059 16.6 13.4 0.023 14.6 0.5 3.1 1 1 2 3 3 3 3 Seven in absentia protein family zf-CCHC PF00098.23 GBG69499.1 - 0.56 10.4 7.3 0.15 12.2 3.5 2.2 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG69500.1 - 3.6e-26 91.1 0.0 5.8e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69500.1 - 3.3e-23 82.0 0.0 5.5e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69500.1 - 1.9e-18 66.3 0.3 3.9e-18 65.3 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69500.1 - 0.0001 22.5 0.0 0.00028 21.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG69500.1 - 0.00011 22.4 0.1 0.00027 21.1 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger EF-hand_4 PF12763.7 GBG69501.1 - 1e-19 70.4 0.0 3.3e-13 49.5 0.0 2.9 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 GBG69501.1 - 4.4e-12 44.6 0.0 0.0024 17.3 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 GBG69501.1 - 2e-08 34.6 0.0 0.0038 17.6 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GBG69501.1 - 5.4e-08 32.2 0.1 0.24 11.4 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 GBG69501.1 - 0.00011 21.5 0.3 0.0091 15.5 0.1 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 GBG69501.1 - 0.00029 20.6 0.1 0.67 9.8 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair PALP PF00291.25 GBG69503.1 - 1.7e-60 204.9 1.9 2.7e-60 204.3 1.9 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RVT_1 PF00078.27 GBG69503.1 - 4.9e-43 147.2 1.3 8e-21 74.6 0.3 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69503.1 - 8.7e-21 74.2 0.0 2.1e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69503.1 - 7.9e-19 67.6 0.0 8.8e-09 35.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Glycos_transf_N PF04413.16 GBG69503.1 - 0.12 12.0 0.0 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Atg14 PF10186.9 GBG69504.1 - 1.3e-27 96.8 0.0 1.7e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF503 PF04456.12 GBG69504.1 - 0.14 12.0 0.4 5.5 6.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF503) DUF5401 PF17380.2 GBG69506.1 - 0.22 9.5 21.7 0.29 9.1 21.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) FTHFS PF01268.19 GBG69506.1 - 0.5 8.5 3.4 0.7 8.0 3.4 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase FAM60A PF15396.6 GBG69506.1 - 7.4 6.5 9.4 13 5.7 9.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CAF1 PF04857.20 GBG69506.1 - 8.9 5.4 7.1 15 4.6 7.0 1.5 2 0 0 2 2 2 0 CAF1 family ribonuclease Retrotrans_gag PF03732.17 GBG69507.1 - 5.6e-05 23.3 8.5 0.00027 21.2 0.1 4.3 4 2 0 4 4 4 1 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG69507.1 - 0.14 12.2 7.2 1.1 9.4 0.0 3.2 3 1 1 4 4 4 0 TolA binding protein trimerisation Baculo_PEP_C PF04513.12 GBG69507.1 - 0.19 11.7 0.8 1.1 9.2 0.4 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EutC PF05985.11 GBG69507.1 - 0.71 9.1 7.2 2.5 7.3 7.2 1.9 1 1 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) RVT_1 PF00078.27 GBG69508.1 - 3e-26 92.3 2.1 1.4e-25 90.1 0.3 2.6 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG69508.1 - 0.00019 21.6 7.7 0.00057 20.1 0.1 4.4 4 2 0 4 4 4 1 Retrotransposon gag protein EutC PF05985.11 GBG69508.1 - 0.27 10.5 4.3 0.76 9.0 4.3 1.8 1 1 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) TolA_bind_tri PF16331.5 GBG69508.1 - 4.2 7.5 10.3 2.2 8.4 0.0 3.5 4 0 0 4 4 4 0 TolA binding protein trimerisation KH_7 PF17214.3 GBG69510.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 KH domain RVT_1 PF00078.27 GBG69512.1 - 6.5e-19 68.3 0.1 9.8e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG69512.1 - 0.35 10.2 21.1 0.49 9.7 21.1 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GBG69512.1 - 0.51 10.0 16.2 0.82 9.4 16.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG69512.1 - 5.5 6.3 19.3 7.3 5.9 19.3 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG69512.1 - 6 5.3 19.5 8.2 4.9 19.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GBG69512.1 - 6.4 4.9 15.2 8.6 4.5 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein His_Phos_2 PF00328.22 GBG69513.1 - 1.7 7.9 6.2 0.68 9.2 1.2 1.9 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) HU-CCDC81_bac_2 PF18175.1 GBG69514.1 - 0.0053 16.6 1.2 0.078 12.9 0.3 2.9 2 0 0 2 2 2 1 CCDC81-like prokaryotic HU domain 2 DUF2730 PF10805.8 GBG69514.1 - 0.036 14.2 0.5 0.13 12.3 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) RVT_1 PF00078.27 GBG69515.1 - 4.7e-28 98.2 0.2 8.7e-28 97.4 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69515.1 - 2e-26 91.9 0.0 4.9e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69515.1 - 3.1e-22 78.9 0.0 5.8e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69515.1 - 7.6e-18 64.4 2.7 2e-16 59.8 1.3 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain CBF PF03914.17 GBG69517.1 - 1.6e-51 174.8 0.6 1.3e-49 168.5 0.2 3.7 3 1 0 3 3 3 1 CBF/Mak21 family Adaptin_N PF01602.20 GBG69517.1 - 5.2e-05 22.0 0.4 0.00066 18.4 0.0 2.0 2 0 0 2 2 2 1 Adaptin N terminal region bMG1 PF17970.1 GBG69517.1 - 0.037 14.1 0.2 0.083 13.0 0.2 1.6 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG1 domain DUF1858 PF08984.11 GBG69517.1 - 0.053 13.7 0.0 0.72 10.1 0.0 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1858) YL1 PF05764.13 GBG69518.1 - 0.00063 19.9 41.7 0.00073 19.7 41.7 1.0 1 0 0 1 1 1 1 YL1 nuclear protein SR-25 PF10500.9 GBG69518.1 - 0.0038 16.9 24.7 0.0046 16.6 24.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 GBG69518.1 - 0.0055 15.1 32.1 0.0057 15.0 32.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop53 PF07767.11 GBG69518.1 - 0.028 13.8 43.6 0.035 13.5 43.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) NAM-associated PF14303.6 GBG69518.1 - 0.037 14.7 28.0 0.043 14.5 28.0 1.0 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF3807 PF12720.7 GBG69518.1 - 0.099 12.9 29.0 0.11 12.7 29.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Rrn6 PF10214.9 GBG69518.1 - 0.12 10.8 12.0 0.13 10.7 12.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DAG_kinase_N PF14513.6 GBG69518.1 - 0.13 12.5 11.4 0.15 12.3 11.4 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Nop14 PF04147.12 GBG69518.1 - 0.15 10.3 37.4 0.17 10.1 37.4 1.0 1 0 0 1 1 1 0 Nop14-like family GAGA_bind PF06217.12 GBG69518.1 - 0.26 11.5 19.5 0.26 11.5 19.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family SDA1 PF05285.12 GBG69518.1 - 0.27 10.6 40.5 0.33 10.3 40.5 1.1 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 GBG69518.1 - 0.52 10.1 27.8 0.75 9.6 27.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Drc1-Sld2 PF11719.8 GBG69518.1 - 0.63 9.5 28.4 0.84 9.1 28.4 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Cwf_Cwc_15 PF04889.12 GBG69518.1 - 1.1 8.9 39.1 1.3 8.7 39.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CCDC106 PF15794.5 GBG69518.1 - 1.6 8.4 22.0 1.9 8.1 22.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF2052 PF09747.9 GBG69518.1 - 2.3 8.3 32.5 3 7.9 32.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4614 PF15391.6 GBG69518.1 - 3 7.8 14.0 3.3 7.7 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SLC12 PF03522.15 GBG69518.1 - 4.1 6.3 18.6 4.6 6.2 18.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4569 PF15133.6 GBG69518.1 - 4.5 6.9 14.9 5.2 6.7 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CENP-N PF05238.13 GBG69518.1 - 4.8 6.4 19.6 6.2 6.0 19.6 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Presenilin PF01080.17 GBG69518.1 - 5 5.8 20.6 5.7 5.6 20.6 1.0 1 0 0 1 1 1 0 Presenilin Merozoite_SPAM PF07133.11 GBG69518.1 - 5.3 7.0 48.0 6.9 6.6 48.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) eIF3_subunit PF08597.10 GBG69518.1 - 5.4 6.9 50.7 7 6.5 50.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2828 PF11443.8 GBG69518.1 - 5.9 4.8 19.4 6.5 4.7 19.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FGF-BP1 PF06473.12 GBG69518.1 - 6.8 6.4 23.0 9.2 6.0 23.0 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Apt1 PF10351.9 GBG69518.1 - 6.9 5.4 18.3 7.9 5.2 18.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain ALMT PF11744.8 GBG69518.1 - 8.2 5.1 14.0 8.3 5.1 14.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter TPT PF03151.16 GBG69519.1 - 1.4e-10 41.1 12.6 1.6e-10 40.8 12.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GBG69519.1 - 2.2e-05 23.9 12.6 0.00014 21.2 13.5 1.8 2 0 0 2 2 2 1 UAA transporter family His_biosynth PF00977.21 GBG69520.1 - 6.1e-46 156.7 0.0 3.2e-45 154.4 0.0 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 GBG69520.1 - 4.8e-20 72.1 0.0 7.7e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 GBG69520.1 - 1.1e-08 35.0 0.0 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 GBG69520.1 - 2.7e-07 30.6 0.0 2.5e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 GBG69520.1 - 0.0079 16.0 0.0 4.1 7.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase C26 ThiG PF05690.14 GBG69520.1 - 0.011 15.0 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PS_Dcarbxylase PF02666.15 GBG69522.1 - 7.9e-38 130.0 0.0 1.3e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase LIG3_BRCT PF16759.5 GBG69522.1 - 0.0046 17.2 0.0 3.2 8.1 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain hNIFK_binding PF12196.8 GBG69522.1 - 0.02 14.4 0.0 10 5.7 0.0 2.7 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK RVP_2 PF08284.11 GBG69523.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69523.1 - 0.077 13.6 0.0 0.25 12.0 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG69523.1 - 0.12 13.0 0.1 1 9.9 0.0 2.6 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease EF-hand_7 PF13499.6 GBG69524.1 - 5.4e-12 46.0 0.3 1.6e-08 34.8 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG69524.1 - 9.1e-12 43.6 0.2 5.7e-05 22.4 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GBG69524.1 - 4.1e-09 35.6 0.2 0.0029 17.4 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GBG69524.1 - 4.7e-09 35.3 2.1 0.0026 17.2 0.0 3.0 3 0 0 3 3 3 2 EF hand C2 PF00168.30 GBG69524.1 - 2.6e-06 27.7 0.1 1.3e-05 25.4 0.0 2.0 1 1 1 2 2 2 1 C2 domain EF-hand_8 PF13833.6 GBG69524.1 - 9.6e-06 25.4 0.5 0.063 13.1 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair zf-C2H2_9 PF16293.5 GBG69524.1 - 0.097 12.5 0.2 2.4 8.1 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DUF1389 PF07146.11 GBG69524.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) RVT_1 PF00078.27 GBG69525.1 - 1.6e-32 112.8 0.1 2.9e-32 112.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG69525.1 - 5.2e-12 45.5 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ThiF PF00899.21 GBG69526.1 - 1.6e-71 240.5 0.1 2.6e-71 239.9 0.1 1.3 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 GBG69526.1 - 2.8e-18 66.3 0.0 6.2e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 GBG69526.1 - 4e-07 30.2 0.0 0.00024 21.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site E2_bind PF08825.10 GBG69526.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 E2 binding domain NAD_binding_7 PF13241.6 GBG69526.1 - 0.028 14.8 0.0 0.084 13.3 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 GBG69526.1 - 0.047 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Tenui_NS3 PF05310.12 GBG69526.1 - 0.14 12.3 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 Tenuivirus movement protein zf-C3HC4 PF00097.25 GBG69527.1 - 4.8e-07 29.6 6.6 1.4e-06 28.1 5.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG69527.1 - 8.3e-06 26.0 7.8 8.7e-06 26.0 6.4 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG69527.1 - 1.5e-05 24.9 6.7 1.5e-05 24.9 6.7 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GBG69527.1 - 2.4e-05 24.1 14.5 0.0004 20.2 9.3 3.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG69527.1 - 8.7e-05 22.4 7.0 0.00012 21.9 4.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GBG69527.1 - 0.00032 20.5 3.9 0.00073 19.3 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PAM2 PF07145.15 GBG69527.1 - 0.017 14.8 0.7 0.049 13.3 0.7 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region REV PF00424.18 GBG69527.1 - 0.047 13.7 1.0 0.12 12.4 1.0 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) zf-C3HC4_4 PF15227.6 GBG69527.1 - 0.05 13.8 8.5 0.12 12.5 8.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GBG69527.1 - 0.11 12.4 3.7 0.37 10.7 3.7 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GBG69527.1 - 0.15 12.4 4.4 0.4 11.0 4.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 GBG69527.1 - 3.7 7.4 6.5 7.4 6.4 6.5 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 GBG69527.1 - 6.1 6.7 7.2 5.4 6.9 5.0 2.2 2 0 0 2 2 2 0 RING-like zinc finger MULE PF10551.9 GBG69528.1 - 2.2e-16 60.1 0.0 4.9e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG69528.1 - 2.8e-10 40.0 1.3 5.9e-10 39.0 1.3 1.5 1 0 0 1 1 1 1 MuDR family transposase SWIM PF04434.17 GBG69528.1 - 0.0031 17.1 0.9 0.0031 17.1 0.9 2.6 2 0 0 2 2 2 1 SWIM zinc finger Transposase_mut PF00872.18 GBG69528.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family TMEM119 PF15724.5 GBG69528.1 - 0.026 14.6 0.5 0.046 13.8 0.5 1.3 1 0 0 1 1 1 0 TMEM119 family WXG100 PF06013.12 GBG69528.1 - 2 8.7 3.7 41 4.5 1.4 2.8 2 0 0 2 2 2 0 Proteins of 100 residues with WXG HEM4 PF02602.15 GBG69529.1 - 4.5e-13 49.1 0.0 3.3e-07 29.9 0.0 4.3 4 1 1 5 5 5 3 Uroporphyrinogen-III synthase HemD WD40 PF00400.32 GBG69530.1 - 7.7e-39 131.0 12.8 9.6e-07 29.4 0.3 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG69530.1 - 1.3e-11 44.6 0.1 0.00016 21.9 0.2 5.0 2 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG69530.1 - 1.3e-06 28.5 0.1 0.0075 16.2 0.0 3.2 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GBG69530.1 - 0.00071 18.3 2.7 0.11 11.1 0.0 3.7 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Frtz PF11768.8 GBG69530.1 - 0.031 12.6 0.0 1.2 7.4 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 GBG69530.1 - 0.034 13.5 0.1 9.4 5.5 0.0 3.1 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal RVT_1 PF00078.27 GBG69531.1 - 2.1e-28 99.4 0.1 3.3e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Utp14 PF04615.13 GBG69531.1 - 1.2 7.6 14.1 2 6.9 14.1 1.2 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 GBG69531.1 - 9.9 5.4 35.5 5 6.4 33.6 1.4 1 1 0 1 1 1 0 BUD22 CCDC92 PF14916.6 GBG69533.1 - 0.012 15.3 15.5 10 6.0 0.2 6.1 6 0 0 6 6 6 0 Coiled-coil domain of unknown function Prominin PF05478.11 GBG69533.1 - 0.045 11.7 0.2 0.091 10.7 0.2 1.5 1 0 0 1 1 1 0 Prominin OmpH PF03938.14 GBG69533.1 - 0.29 11.5 19.2 5.4 7.3 5.1 3.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Pectinesterase PF01095.19 GBG69535.1 - 1.8e-60 204.2 1.2 2.2e-60 203.9 1.2 1.0 1 0 0 1 1 1 1 Pectinesterase EF-hand_1 PF00036.32 GBG69537.1 - 5e-15 53.8 14.1 0.0001 21.6 0.6 5.3 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 GBG69537.1 - 1e-13 51.5 4.5 0.00068 20.0 1.2 4.8 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 GBG69537.1 - 5.9e-13 47.7 8.9 7.9e-05 22.0 0.8 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GBG69537.1 - 2.4e-12 45.7 13.6 0.00019 21.1 0.1 5.5 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 GBG69537.1 - 4.4e-11 42.4 17.7 0.00037 20.3 0.9 5.1 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.7 GBG69537.1 - 0.0003 20.7 2.2 3.5 7.6 0.1 3.4 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 GBG69537.1 - 0.11 12.7 0.1 55 4.1 0.4 3.4 3 1 1 4 4 4 0 Dockerin type I domain SOBP PF15279.6 GBG69537.1 - 0.46 11.0 3.5 0.82 10.2 3.5 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Caldesmon PF02029.15 GBG69538.1 - 0.00011 21.1 18.2 0.00013 20.9 18.2 1.1 1 0 0 1 1 1 1 Caldesmon Mpp10 PF04006.12 GBG69538.1 - 0.0021 16.6 23.6 0.0027 16.2 23.6 1.1 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 GBG69538.1 - 0.0087 15.5 28.7 0.012 15.1 28.7 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG69538.1 - 0.03 12.6 19.6 0.037 12.3 19.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GBG69538.1 - 0.33 9.4 15.8 0.42 9.1 15.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 GBG69538.1 - 0.46 10.2 19.9 1.5 8.6 19.9 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.8 GBG69538.1 - 0.48 9.2 18.0 0.9 8.3 18.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BUD22 PF09073.10 GBG69538.1 - 0.54 9.5 32.7 0.75 9.1 32.7 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG69538.1 - 0.77 9.3 18.0 1.1 8.7 18.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LRRC37AB_C PF14914.6 GBG69538.1 - 0.88 9.5 6.6 1.6 8.6 6.6 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain MID_MedPIWI PF18296.1 GBG69538.1 - 1.2 8.9 6.3 2 8.2 6.3 1.5 1 0 0 1 1 1 0 MID domain of medPIWI SpoIIP PF07454.11 GBG69538.1 - 1.2 8.5 15.7 1.6 8.1 15.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CSG2 PF16965.5 GBG69538.1 - 2.1 7.2 4.5 3.3 6.6 4.5 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Utp14 PF04615.13 GBG69538.1 - 2.5 6.6 26.6 3.3 6.2 26.6 1.1 1 0 0 1 1 1 0 Utp14 protein Connexin PF00029.19 GBG69538.1 - 2.7 7.7 12.2 4.3 7.0 12.2 1.3 1 0 0 1 1 1 0 Connexin BAF1_ABF1 PF04684.13 GBG69538.1 - 4 6.4 20.0 6 5.8 20.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 GBG69538.1 - 4.8 6.1 8.3 6 5.8 8.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 GBG69538.1 - 5.4 5.7 11.3 7.8 5.2 11.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-3c_N PF05470.12 GBG69538.1 - 5.6 5.2 18.1 7.3 4.8 18.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3402 PF11882.8 GBG69538.1 - 8.1 5.4 10.6 10 5.1 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) DUF3292 PF11696.8 GBG69538.1 - 8.6 4.6 9.6 13 4.0 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CAF1 PF04857.20 GBG69538.1 - 8.7 5.4 7.6 14 4.7 7.6 1.4 1 0 0 1 1 1 0 CAF1 family ribonuclease Peptidase_S64 PF08192.11 GBG69538.1 - 9.4 4.6 16.3 11 4.3 16.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 MULE PF10551.9 GBG69539.1 - 6.5e-21 74.6 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 GBG69539.1 - 1.4e-07 30.8 0.0 2.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DBD_Tnp_Mut PF03108.15 GBG69539.1 - 0.00093 19.1 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 MuDR family transposase PALP PF00291.25 GBG69540.1 - 1.8e-18 67.0 0.1 2.4e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 5_nucleotid PF05761.14 GBG69541.1 - 2.3e-170 567.4 0.5 2.8e-170 567.2 0.5 1.1 1 0 0 1 1 1 1 5' nucleotidase family SelK_SelG PF10961.8 GBG69541.1 - 0.0037 17.8 2.9 0.011 16.3 2.9 1.8 1 0 0 1 1 1 1 Selenoprotein SelK_SelG YabA PF06156.13 GBG69541.1 - 0.45 11.2 2.0 0.91 10.2 2.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Radial_spoke_3 PF06098.11 GBG69541.1 - 1.2 8.4 5.7 1.9 7.7 5.7 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 AAA PF00004.29 GBG69545.1 - 5.7e-90 298.6 0.0 1.7e-47 161.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG69545.1 - 6.3e-23 80.3 7.1 3.6e-12 45.9 2.0 2.9 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 GBG69545.1 - 6.9e-14 51.9 0.0 1.4e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GBG69545.1 - 1.9e-12 47.9 1.8 0.00037 20.9 0.0 4.7 4 2 1 5 5 4 2 AAA ATPase domain Nucleolin_bd PF16725.5 GBG69545.1 - 1.9e-12 46.6 2.8 4.2e-12 45.6 2.8 1.5 1 0 0 1 1 1 1 Nucleolin binding domain AAA_2 PF07724.14 GBG69545.1 - 8.7e-11 42.2 0.0 0.00018 21.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GBG69545.1 - 1.6e-09 37.9 0.1 0.0022 18.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GBG69545.1 - 8.5e-09 35.1 0.0 0.00023 20.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 GBG69545.1 - 6.5e-08 32.9 0.2 0.12 12.6 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GBG69545.1 - 9.5e-08 32.3 0.0 0.017 15.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 GBG69545.1 - 1.3e-07 32.0 0.0 0.032 14.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 GBG69545.1 - 7e-07 29.0 2.6 0.47 10.0 0.0 4.6 4 1 0 5 5 4 2 AAA domain Mg_chelatase PF01078.21 GBG69545.1 - 1.2e-06 28.1 0.5 0.032 13.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 GBG69545.1 - 1.6e-06 28.1 0.0 0.012 15.6 0.0 3.1 3 0 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.17 GBG69545.1 - 3.6e-06 26.8 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 GBG69545.1 - 8.5e-06 25.8 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GBG69545.1 - 1.9e-05 25.2 0.3 0.14 12.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_3 PF07726.11 GBG69545.1 - 2.2e-05 24.3 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 GBG69545.1 - 2.5e-05 23.6 0.0 0.033 13.5 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 GBG69545.1 - 2.6e-05 24.2 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GBG69545.1 - 2.9e-05 24.4 1.0 0.35 11.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain Rad17 PF03215.15 GBG69545.1 - 8.4e-05 22.6 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_17 PF13207.6 GBG69545.1 - 0.00022 21.7 1.9 0.49 10.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 GBG69545.1 - 0.00023 20.4 0.5 1.3 8.0 0.0 3.0 3 0 0 3 3 3 2 Parvovirus non-structural protein NS1 ATPase PF06745.13 GBG69545.1 - 0.00027 20.4 0.0 2.2 7.6 0.0 3.4 3 0 0 3 3 3 1 KaiC ABC_tran PF00005.27 GBG69545.1 - 0.00033 21.2 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 GBG69545.1 - 0.00063 19.5 0.0 0.88 9.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 GBG69545.1 - 0.00093 18.8 0.0 2 7.9 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 GBG69545.1 - 0.00095 19.1 0.2 0.85 9.7 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NB-ARC PF00931.22 GBG69545.1 - 0.001 18.3 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.6 GBG69545.1 - 0.0015 18.7 0.0 0.39 10.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 GBG69545.1 - 0.0016 18.0 0.0 0.89 9.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ATPase_2 PF01637.18 GBG69545.1 - 0.0016 18.4 0.0 2.8 7.8 0.0 2.6 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_24 PF13479.6 GBG69545.1 - 0.0039 17.0 0.1 1.2 8.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 GBG69545.1 - 0.013 15.7 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family Viral_helicase1 PF01443.18 GBG69545.1 - 0.018 14.8 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 GBG69545.1 - 0.037 13.8 5.1 3.2 7.5 0.0 3.5 5 0 0 5 5 3 0 AAA domain AAA_19 PF13245.6 GBG69545.1 - 0.038 14.3 0.0 13 6.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 GBG69545.1 - 0.057 13.3 1.2 0.88 9.4 0.0 2.9 3 1 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 GBG69545.1 - 0.08 12.3 0.0 12 5.2 0.0 3.1 2 1 0 3 3 3 0 Bacterial TniB protein AAA_23 PF13476.6 GBG69545.1 - 0.083 13.4 0.0 11 6.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 GBG69545.1 - 0.1 11.7 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 GBG69545.1 - 0.14 11.3 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AFG1_ATPase PF03969.16 GBG69545.1 - 0.17 10.8 0.1 0.46 9.3 0.0 1.7 2 0 0 2 2 1 0 AFG1-like ATPase DHHA1 PF02272.19 GBG69547.1 - 0.017 15.5 0.3 0.074 13.5 0.0 2.0 2 0 0 2 2 2 0 DHHA1 domain DUF1564 PF07600.11 GBG69547.1 - 0.097 12.4 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Integrase_H2C2 PF17921.1 GBG69548.1 - 2.2e-13 50.1 0.1 4.9e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69548.1 - 5e-07 29.9 0.0 9.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG69548.1 - 0.00065 20.2 0.0 0.0015 19.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69548.1 - 0.0014 19.2 0.0 0.003 18.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG69548.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TraI PF07057.11 GBG69548.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 DNA helicase TraI TMEM215 PF15746.5 GBG69549.1 - 0.063 12.7 0.9 0.091 12.2 0.9 1.2 1 0 0 1 1 1 0 TMEM215 family RVT_1 PF00078.27 GBG69553.1 - 1.2e-27 96.8 0.1 2.6e-27 95.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69553.1 - 1.1e-25 89.5 0.0 9.7e-25 86.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69553.1 - 5.9e-22 77.9 0.0 2.2e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69553.1 - 1.1e-18 67.1 0.3 3.7e-18 65.4 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69553.1 - 4.8e-08 33.2 0.0 1.7e-07 31.5 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG69553.1 - 9.4e-07 29.4 0.0 2.6e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69553.1 - 1.4e-06 28.2 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG69553.1 - 4e-06 27.3 0.0 1.3e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease HIP1_clath_bdg PF16515.5 GBG69553.1 - 0.0049 17.4 4.8 0.0049 17.4 4.8 3.6 4 0 0 4 4 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Asp_protease PF09668.10 GBG69553.1 - 0.0061 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG69553.1 - 0.025 14.5 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF421 PF04239.12 GBG69553.1 - 0.17 11.6 0.1 0.38 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Rotamase_2 PF13145.6 GBG69553.1 - 3.3 8.6 6.9 9.3 7.1 6.9 1.7 1 0 0 1 1 1 0 PPIC-type PPIASE domain DUF2408 PF10303.9 GBG69553.1 - 8.8 6.9 7.7 14 6.3 5.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Acyltransferase PF01553.21 GBG69554.1 - 5.3e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase LTXXQ PF07813.12 GBG69554.1 - 0.011 16.4 2.1 0.034 14.9 2.1 1.8 1 0 0 1 1 1 0 LTXXQ motif family protein DUF2855 PF11017.8 GBG69555.1 - 0.05 13.3 2.5 0.12 12.1 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) CDC45 PF02724.14 GBG69560.1 - 0.3 9.3 0.3 0.26 9.5 0.3 1.0 1 0 0 1 1 1 0 CDC45-like protein RVP_2 PF08284.11 GBG69561.1 - 0.00069 19.4 0.0 0.0051 16.6 0.0 2.4 3 0 0 3 3 3 1 Retroviral aspartyl protease Cwf_Cwc_15 PF04889.12 GBG69561.1 - 0.0019 18.0 24.5 1.1 8.9 25.4 2.2 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Lin-8 PF03353.15 GBG69561.1 - 0.028 14.0 12.1 0.046 13.3 12.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Asp_protease PF09668.10 GBG69561.1 - 0.052 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG69561.1 - 0.17 12.5 0.0 0.44 11.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Nop14 PF04147.12 GBG69561.1 - 5.2 5.2 29.3 7.5 4.6 29.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG69561.1 - 5.4 5.2 22.7 8.5 4.5 22.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH PF17917.1 GBG69563.1 - 4.9e-23 81.4 0.0 1.2e-22 80.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69563.1 - 3e-21 75.3 0.0 7e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69563.1 - 1.4e-13 50.8 0.3 3.1e-13 49.6 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69563.1 - 9.6e-13 48.4 0.2 2.5e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG69563.1 - 3e-05 24.5 0.1 7.1e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG69563.1 - 3.8e-05 23.3 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG69563.1 - 0.00012 22.6 0.0 0.00028 21.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG69563.1 - 0.072 13.3 0.3 0.19 11.9 0.3 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 GBG69563.1 - 0.17 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Fasciclin PF02469.22 GBG69564.1 - 2.2e-59 199.3 0.0 1.5e-21 77.0 0.1 4.2 4 0 0 4 4 4 4 Fasciclin domain Tub PF01167.18 GBG69566.1 - 5e-32 111.6 0.0 3.6e-16 59.7 0.0 2.5 2 0 0 2 2 2 2 Tub family DUF3527 PF12043.8 GBG69566.1 - 0.0038 16.8 0.0 0.0038 16.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) Cyclase_polyket PF04673.12 GBG69567.1 - 0.064 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Polyketide synthesis cyclase T4SS PF07996.11 GBG69568.1 - 0.053 13.9 0.8 0.1 13.0 0.8 1.5 1 0 0 1 1 1 0 Type IV secretion system proteins SAP18 PF06487.12 GBG69571.1 - 7.9e-40 136.3 0.0 1.2e-39 135.6 0.0 1.3 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Rad60-SLD PF11976.8 GBG69571.1 - 0.015 15.1 0.0 2 8.3 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like zf-CCHC PF00098.23 GBG69574.1 - 0.00024 21.0 2.5 0.00045 20.2 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle AAA_23 PF13476.6 GBG69574.1 - 0.056 13.9 13.9 0.07 13.6 13.9 1.2 1 0 0 1 1 1 0 AAA domain zf-CCHC_5 PF14787.6 GBG69574.1 - 0.07 12.9 0.4 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG69574.1 - 0.37 10.7 3.9 0.62 9.9 3.9 1.3 1 0 0 1 1 1 0 Zinc knuckle ISG65-75 PF11727.8 GBG69574.1 - 0.44 9.7 19.6 0.66 9.2 19.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein SPATIAL PF15256.6 GBG69574.1 - 0.56 10.5 8.2 0.96 9.8 8.2 1.4 1 0 0 1 1 1 0 SPATIAL Herpes_UL6 PF01763.16 GBG69574.1 - 0.89 8.0 8.2 1.1 7.6 8.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like eIF-3c_N PF05470.12 GBG69574.1 - 1.6 7.0 17.3 1.9 6.7 17.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ureide_permease PF07168.11 GBG69574.1 - 4.2 6.0 9.2 5.5 5.6 9.2 1.3 1 0 0 1 1 1 0 Ureide permease CAF-1_p150 PF11600.8 GBG69574.1 - 6.3 6.5 43.3 0.076 12.7 34.6 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.17 GBG69574.1 - 7.4 6.7 10.0 11 6.1 10.0 1.4 1 0 0 1 1 1 0 DDHD domain Rgp1 PF08737.10 GBG69574.1 - 8.1 5.5 13.4 10 5.1 13.4 1.1 1 0 0 1 1 1 0 Rgp1 XRN_M PF17846.1 GBG69574.1 - 9.8 5.0 14.5 13 4.6 14.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain BPL_LplA_LipB PF03099.19 GBG69575.1 - 1.3e-19 70.4 0.0 2.6e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 GBG69575.1 - 0.016 15.1 0.1 0.05 13.5 0.1 1.9 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Pox_A21 PF05323.12 GBG69577.1 - 0.23 12.0 0.0 0.66 10.6 0.0 1.7 1 0 0 1 1 1 0 Poxvirus A21 Protein PHD PF00628.29 GBG69578.1 - 1.7e-11 43.8 8.4 1.7e-11 43.8 8.4 2.3 2 0 0 2 2 2 1 PHD-finger zf-C2H2 PF00096.26 GBG69578.1 - 0.011 16.1 1.0 0.011 16.1 1.0 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 GBG69578.1 - 7.7 6.4 10.2 0.5 10.2 3.3 2.5 3 0 0 3 3 3 0 zinc-finger C2H2-type DAO PF01266.24 GBG69579.1 - 7.2e-57 193.5 0.3 1.1e-56 193.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GBG69579.1 - 0.0017 18.5 0.5 0.0067 16.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 GBG69579.1 - 0.0036 16.6 0.1 0.0062 15.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 GBG69579.1 - 0.0065 15.8 0.1 0.53 9.5 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GBG69579.1 - 0.0073 15.6 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GBG69579.1 - 0.0086 15.3 0.2 0.017 14.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GBG69579.1 - 0.018 14.1 0.3 0.042 12.9 0.3 1.5 1 1 0 1 1 1 0 FAD binding domain Mqo PF06039.15 GBG69579.1 - 0.082 11.4 0.0 0.18 10.3 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_7 PF13241.6 GBG69579.1 - 0.087 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 GBG69579.1 - 0.1 13.2 0.1 0.32 11.6 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GBG69579.1 - 0.15 12.3 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Aminotran_5 PF00266.19 GBG69581.1 - 3.6e-141 470.4 0.0 5.1e-141 469.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GBG69581.1 - 5.6e-06 25.1 0.0 0.00071 18.2 0.0 2.5 3 0 0 3 3 3 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GBG69581.1 - 2.1e-05 24.0 0.7 4e-05 23.1 0.2 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1497 PF07384.11 GBG69581.1 - 0.038 14.4 0.2 0.094 13.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) DHC_N2 PF08393.13 GBG69582.1 - 8e-05 21.9 0.1 8e-05 21.9 0.1 2.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 ABC_membrane_3 PF13748.6 GBG69582.1 - 0.16 11.2 0.3 0.27 10.5 0.3 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region YkyA PF10368.9 GBG69582.1 - 0.18 11.4 6.7 1.4 8.6 1.2 2.4 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein HSCB_C PF07743.13 GBG69582.1 - 1.5 9.4 12.0 0.08 13.4 2.7 3.2 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DHC_N2 PF08393.13 GBG69583.1 - 0.0098 15.0 0.1 0.0098 15.0 0.1 2.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 ABC_membrane_3 PF13748.6 GBG69583.1 - 0.14 11.3 0.3 0.24 10.6 0.3 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region YkyA PF10368.9 GBG69583.1 - 0.15 11.7 6.7 1.3 8.7 1.2 2.4 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein AAA_6 PF12774.7 GBG69584.1 - 2.1e-30 105.8 0.1 4.2e-30 104.8 0.1 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 GBG69584.1 - 0.00094 18.4 0.2 0.0016 17.6 0.2 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA PF00004.29 GBG69584.1 - 0.0015 18.9 0.0 0.0046 17.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GBG69584.1 - 0.0037 17.8 0.2 0.019 15.5 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 GBG69584.1 - 0.018 15.3 0.3 0.042 14.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GBG69584.1 - 0.052 13.9 0.5 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 GBG69584.1 - 0.066 13.4 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GBG69584.1 - 0.12 12.8 1.3 1.2 9.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 GBG69584.1 - 0.14 11.9 0.1 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GBG69584.1 - 0.15 11.3 0.0 0.4 9.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Hydin_ADK PF17213.3 GBG69584.1 - 0.17 12.1 0.1 1 9.6 0.0 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Rad17 PF03215.15 GBG69584.1 - 0.18 11.7 0.1 0.46 10.4 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_8 PF12780.7 GBG69585.1 - 2.8e-53 180.9 0.3 3.2e-52 177.4 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_6 PF12774.7 GBG69585.1 - 6e-47 160.2 0.0 8e-24 84.2 0.0 2.3 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region MT PF12777.7 GBG69585.1 - 2.1e-40 138.8 3.9 1.1e-39 136.5 4.1 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 GBG69585.1 - 4.7e-37 127.3 0.0 1.9e-33 115.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_9 PF12781.7 GBG69585.1 - 6.4e-36 123.5 0.0 6.4e-36 123.5 0.0 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_AAA_lid PF17852.1 GBG69585.1 - 5.7e-16 58.8 0.0 2e-13 50.5 0.1 3.2 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 GBG69585.1 - 2.8e-14 53.1 0.0 6.6e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GBG69585.1 - 3.5e-11 43.3 0.0 0.035 14.1 0.0 4.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GBG69585.1 - 2.5e-06 27.8 0.2 0.074 13.3 0.0 4.1 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 GBG69585.1 - 1.1e-05 25.8 0.0 0.22 12.0 0.0 4.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 GBG69585.1 - 0.0035 16.5 0.0 3.3 6.8 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 GBG69585.1 - 0.0075 16.7 13.7 0.5 10.7 0.1 5.5 4 1 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.6 GBG69585.1 - 0.0085 16.3 0.1 9.5 6.4 0.0 3.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GBG69585.1 - 0.01 15.2 0.2 0.79 9.1 0.1 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 GBG69585.1 - 0.014 15.1 0.0 3.1 7.6 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GBG69585.1 - 0.015 14.6 0.3 3 7.1 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin Spc7 PF08317.11 GBG69585.1 - 0.015 14.2 22.4 0.14 11.1 5.8 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_19 PF13245.6 GBG69585.1 - 0.047 14.0 0.1 10 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GBG69585.1 - 0.059 13.3 0.7 2.1 8.2 0.0 3.0 2 1 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 GBG69585.1 - 0.16 11.5 1.3 8.5 5.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 GBG69585.1 - 0.19 12.2 0.1 3 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 GBG69585.1 - 0.28 10.5 3.0 0.8 9.0 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family ABC_tran PF00005.27 GBG69585.1 - 0.41 11.2 5.3 8.8 6.9 0.0 3.6 4 0 0 4 4 3 0 ABC transporter SHE3 PF17078.5 GBG69585.1 - 4.5 6.9 18.9 9.2 5.9 7.0 2.7 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF3450 PF11932.8 GBG69585.1 - 4.8 6.4 20.0 1.6 8.0 2.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 GBG69585.1 - 4.8 7.2 11.3 2.7 8.1 5.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 GBG69585.1 - 8 6.8 12.4 3 8.2 1.1 3.7 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF5082 PF16888.5 GBG69585.1 - 9.6 6.5 15.9 0.28 11.5 5.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Iso_dh PF00180.20 GBG69587.1 - 1.4e-08 34.3 0.0 1.6e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RVT_1 PF00078.27 GBG69588.1 - 9.8e-27 93.9 0.0 1.5e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG69588.1 - 0.22 12.2 0.0 0.49 11.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 GBG69589.1 - 3.1e-12 46.7 0.0 7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Ser_hydrolase PF06821.13 GBG69589.1 - 0.046 13.6 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Atg8 PF02991.16 GBG69590.1 - 1.3e-51 173.1 0.1 1.5e-51 172.9 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 GBG69590.1 - 9.8e-07 29.1 0.0 1.2e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2201 PF09967.9 GBG69590.1 - 0.16 12.1 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 VWA-like domain (DUF2201) Dynein_C PF18199.1 GBG69592.1 - 2.2e-80 270.1 0.0 3.3e-80 269.6 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 GBG69592.1 - 1.4e-31 109.5 0.0 4.6e-15 55.8 0.0 2.7 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain RVT_1 PF00078.27 GBG69592.1 - 1.1e-25 90.4 0.0 3.3e-25 88.9 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69592.1 - 1.3e-23 82.9 0.0 2.8e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69592.1 - 3.4e-23 81.9 0.0 6.3e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69592.1 - 1.3e-07 31.8 0.0 3.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG69592.1 - 2.1e-07 31.5 0.0 4.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69592.1 - 4.6e-07 29.7 0.0 9.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG69592.1 - 2.2e-05 24.9 0.0 4.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG69592.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Ski_Sno PF02437.17 GBG69592.1 - 0.056 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 SKI/SNO/DAC family AAA_lid_11 PF18198.1 GBG69593.1 - 9.9e-32 110.0 0.0 3.8e-15 56.1 0.0 2.7 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain RVT_1 PF00078.27 GBG69593.1 - 1.2e-25 90.3 0.0 2.7e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69593.1 - 1.1e-23 83.1 0.0 2.3e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69593.1 - 3e-23 82.1 0.0 5.2e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69593.1 - 1.1e-07 32.0 0.0 3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG69593.1 - 1.8e-07 31.7 0.0 3.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69593.1 - 4e-07 29.9 0.0 7.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG69593.1 - 2e-05 25.0 0.0 4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG69593.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG69593.1 - 0.18 12.2 0.0 0.46 10.8 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Dynein_C PF18199.1 GBG69594.1 - 2.4e-74 250.3 0.0 2.8e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Ski_Sno PF02437.17 GBG69594.1 - 0.005 16.6 0.2 0.012 15.4 0.1 1.6 2 0 0 2 2 2 1 SKI/SNO/DAC family DUF2457 PF10446.9 GBG69595.1 - 0.27 10.3 8.1 0.3 10.2 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RT_RNaseH_2 PF17919.1 GBG69596.1 - 3.8e-26 91.0 0.0 6.3e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69596.1 - 3.6e-23 81.9 0.0 6.1e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69596.1 - 1.3e-09 37.9 0.1 1.9e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG69597.1 - 1.1e-14 54.5 0.1 1.5e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-Hacid_dh_C PF02826.19 GBG69598.1 - 1.8e-09 37.2 0.0 4.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GBG69598.1 - 0.014 15.1 0.0 0.072 12.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain CAP_N PF01213.19 GBG69598.1 - 0.52 9.7 13.9 0.68 9.4 0.7 2.6 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal DnaJ PF00226.31 GBG69599.1 - 1.1e-21 76.7 0.1 1.1e-21 76.7 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain RETICULATA-like PF11891.8 GBG69600.1 - 3.2e-52 176.9 0.0 6.6e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 Protein RETICULATA-related RVT_1 PF00078.27 GBG69602.1 - 3.6e-25 88.8 0.6 5.7e-25 88.1 0.2 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69602.1 - 3.2e-15 56.4 0.0 7.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain PhoD PF09423.10 GBG69603.1 - 2.7e-23 82.5 0.0 6.4e-23 81.3 0.0 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase RINGv PF12906.7 GBG69605.1 - 6.2e-11 42.3 8.7 1.2e-10 41.4 8.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.6 GBG69605.1 - 0.079 12.8 4.3 0.18 11.6 4.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3188 PF11384.8 GBG69605.1 - 0.087 12.5 0.7 0.24 11.1 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) zf-RING_2 PF13639.6 GBG69605.1 - 0.15 12.4 8.2 0.1 13.0 6.0 1.8 1 1 1 2 2 2 0 Ring finger domain DUF202 PF02656.15 GBG69605.1 - 0.24 11.9 3.3 0.42 11.1 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) FeThRed_B PF02943.15 GBG69606.1 - 8.2e-38 128.7 3.0 1.2e-37 128.2 3.0 1.2 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain CENP-B_dimeris PF09026.10 GBG69606.1 - 0.55 10.6 12.8 1.7 9.1 12.1 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-MIZ PF02891.20 GBG69607.1 - 3.4e-20 71.5 2.8 6.5e-20 70.6 2.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PHD PF00628.29 GBG69607.1 - 4.6e-07 29.6 14.7 1.5e-06 28.0 5.1 2.4 2 0 0 2 2 2 2 PHD-finger zf-Nse PF11789.8 GBG69607.1 - 4.7e-07 29.5 0.5 1.1e-06 28.4 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 GBG69607.1 - 1.4e-06 27.9 0.1 2.3e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 GBG69607.1 - 0.11 12.6 2.5 0.14 12.2 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 GBG69607.1 - 0.13 11.7 0.2 0.39 10.1 0.2 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PHD_2 PF13831.6 GBG69607.1 - 0.35 10.5 4.6 0.076 12.6 0.4 2.1 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 GBG69607.1 - 2.3 8.2 5.1 1.2 9.1 1.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 UCH PF00443.29 GBG69609.1 - 2.6e-15 56.6 0.8 3.9e-15 56.0 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG69609.1 - 0.0064 16.1 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF659 PF04937.15 GBG69610.1 - 2.8e-18 66.2 0.0 6.5e-18 65.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG69610.1 - 0.00021 21.0 0.1 0.00047 19.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-LITAF-like PF10601.9 GBG69611.1 - 1e-08 35.3 5.9 1.5e-08 34.7 5.9 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Ammonium_transp PF00909.21 GBG69612.1 - 1.6e-126 422.2 29.4 2.1e-126 421.9 29.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_transf_25 PF01755.17 GBG69613.1 - 4.6e-24 85.4 0.0 7e-17 62.0 0.0 2.8 2 2 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF4604 PF15377.6 GBG69613.1 - 0.0068 16.8 4.1 0.011 16.2 4.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Myb_DNA-binding PF00249.31 GBG69614.1 - 3.2e-07 30.4 0.0 9.3e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain DDHD PF02862.17 GBG69614.1 - 0.41 10.8 16.2 0.45 10.6 4.9 2.8 2 0 0 2 2 2 0 DDHD domain Myb_DNA-binding PF00249.31 GBG69615.1 - 3.2e-07 30.4 0.0 9.3e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain DDHD PF02862.17 GBG69615.1 - 0.39 10.8 16.2 0.45 10.6 4.9 2.8 2 0 0 2 2 2 0 DDHD domain CPSF100_C PF13299.6 GBG69615.1 - 9.2 6.4 20.3 0.75 10.0 3.8 3.6 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Sigma70_r3 PF04539.16 GBG69616.1 - 3.4e-24 84.7 6.1 2.6e-19 69.1 1.6 3.4 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r2 PF04542.14 GBG69616.1 - 4.4e-21 74.4 0.2 2.8e-20 71.9 0.1 2.4 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 GBG69616.1 - 1e-18 66.6 3.5 3e-18 65.1 3.5 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 GBG69616.1 - 2.6e-10 40.1 0.0 7.6e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 AF0941-like PF14591.6 GBG69616.1 - 0.14 12.7 0.3 0.32 11.6 0.3 1.5 1 0 0 1 1 1 0 AF0941-like RRM_1 PF00076.22 GBG69617.1 - 1.6e-05 24.6 0.0 3.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG69617.1 - 0.00068 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Aminotran_1_2 PF00155.21 GBG69617.1 - 0.022 13.9 1.2 0.04 13.1 1.2 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II zf-RING_4 PF14570.6 GBG69617.1 - 0.025 14.3 0.7 0.046 13.5 0.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RPA43_OB PF17875.1 GBG69617.1 - 0.047 14.3 0.3 0.55 10.9 0.1 2.6 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I RED_N PF07808.13 GBG69617.1 - 0.16 11.5 8.0 0.081 12.5 4.6 2.0 2 0 0 2 2 2 0 RED-like protein N-terminal region MAS20 PF02064.15 GBG69617.1 - 0.59 10.2 7.2 0.24 11.5 3.3 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor 5_nucleotid PF05761.14 GBG69617.1 - 0.83 8.5 2.7 1.3 7.8 2.7 1.2 1 0 0 1 1 1 0 5' nucleotidase family DUF1525 PF07511.11 GBG69617.1 - 1.7 8.8 11.6 12 6.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) Apt1 PF10351.9 GBG69619.1 - 0.032 13.1 9.7 0.051 12.4 9.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Asn_synthase PF00733.21 GBG69620.1 - 9.6e-98 328.1 2.0 2.5e-58 198.5 0.2 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 GBG69620.1 - 5.2e-36 123.3 0.0 8.9e-36 122.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GBG69620.1 - 2.2e-24 86.2 0.0 4.2e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GBG69620.1 - 1.3e-12 47.7 0.1 4.5e-12 45.9 0.0 1.9 2 1 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 GBG69620.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Nop14 PF04147.12 GBG69621.1 - 1.6 6.8 5.2 1.6 6.9 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family RVP_2 PF08284.11 GBG69622.1 - 3e-07 30.3 0.0 5.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69622.1 - 3e-05 24.6 0.0 9.6e-05 22.9 0.0 1.9 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69622.1 - 3.3e-05 24.3 0.0 8.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG69622.1 - 0.00041 20.1 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease bZIP_2 PF07716.15 GBG69622.1 - 0.13 12.3 3.7 0.61 10.2 3.7 2.2 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 GBG69622.1 - 0.18 11.6 3.0 0.48 10.2 3.0 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4543 PF15076.6 GBG69622.1 - 0.23 11.6 1.4 2.7 8.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4543) ZapB PF06005.12 GBG69622.1 - 0.23 11.9 2.0 0.59 10.6 2.0 1.7 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 GBG69622.1 - 0.24 11.6 1.6 0.6 10.4 1.6 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper GvpL_GvpF PF06386.11 GBG69622.1 - 0.8 9.6 6.0 2.3 8.1 6.0 1.7 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_Maf PF03131.17 GBG69622.1 - 0.87 10.2 5.7 13 6.4 0.2 2.7 2 0 0 2 2 2 0 bZIP Maf transcription factor eIF-5a PF01287.20 GBG69623.1 - 6.6e-25 87.0 0.1 9.2e-25 86.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 GBG69623.1 - 0.0012 18.9 0.1 0.0022 18.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain ABC2_membrane_3 PF12698.7 GBG69624.1 - 0.076 12.1 2.4 0.091 11.9 2.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RVT_1 PF00078.27 GBG69625.1 - 4.7e-24 85.1 0.0 4.6e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69625.1 - 2.8e-22 78.6 0.1 1.1e-21 76.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69625.1 - 9.5e-20 70.8 0.0 3e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69625.1 - 8.9e-17 61.0 0.8 4.2e-16 58.8 0.2 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG69625.1 - 9.5e-08 32.3 0.0 4.6e-07 30.1 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG69625.1 - 0.006 16.8 0.1 0.02 15.1 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG69625.1 - 0.0075 16.5 0.4 0.0075 16.5 0.4 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG69625.1 - 0.11 12.4 0.0 0.72 9.8 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Nop53 PF07767.11 GBG69625.1 - 1.4 8.2 10.9 2.6 7.4 10.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RVT_1 PF00078.27 GBG69626.1 - 1.7e-30 106.2 0.0 2.6e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_6 PF13516.6 GBG69627.1 - 2.2e-12 45.9 3.2 1.2e-05 25.0 0.1 3.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 GBG69627.1 - 2.9e-05 24.3 0.9 0.0046 17.3 0.9 2.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG69627.1 - 0.00048 19.8 1.9 0.039 13.7 2.3 3.1 2 1 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 GBG69627.1 - 0.0006 20.0 2.2 1.5 9.6 0.1 3.8 4 0 0 4 4 4 1 Leucine Rich Repeat Annexin PF00191.20 GBG69629.1 - 2.9e-43 145.8 0.1 7.7e-15 54.7 0.0 4.1 4 0 0 4 4 4 4 Annexin PhoU PF01895.19 GBG69629.1 - 0.052 14.0 0.5 4.2 7.9 0.0 2.5 2 0 0 2 2 2 0 PhoU domain Annexin PF00191.20 GBG69630.1 - 5.8e-42 141.6 0.2 1.4e-14 53.9 0.0 4.1 4 0 0 4 4 4 4 Annexin PhoU PF01895.19 GBG69630.1 - 0.00047 20.5 1.0 0.07 13.6 0.0 2.6 2 0 0 2 2 2 2 PhoU domain Annexin PF00191.20 GBG69631.1 - 6.4e-45 151.1 0.7 8.1e-16 57.9 0.1 4.2 4 0 0 4 4 4 4 Annexin Annexin PF00191.20 GBG69632.1 - 8.6e-47 157.1 0.4 2.9e-14 52.9 0.0 4.1 4 0 0 4 4 4 4 Annexin RT_RNaseH_2 PF17919.1 GBG69633.1 - 1.3e-23 82.9 0.0 3.6e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69633.1 - 1.1e-22 80.3 0.0 3.2e-22 78.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG69633.1 - 0.0026 18.0 0.2 0.0026 18.0 0.2 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein FAM76 PF16046.5 GBG69633.1 - 1.9 7.8 7.8 1.2 8.4 5.6 1.7 2 0 0 2 2 2 0 FAM76 protein Tnp_22_dsRBD PF17490.2 GBG69634.1 - 0.032 14.2 0.0 9 6.4 0.0 2.6 2 0 0 2 2 2 0 L1 transposable element dsRBD-like domain V-ATPase_G PF03179.15 GBG69636.1 - 0.025 15.1 4.4 0.025 15.1 4.4 2.5 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit WD40 PF00400.32 GBG69637.1 - 5.5e-16 58.7 11.0 9.8e-07 29.4 0.1 5.1 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 GBG69637.1 - 2.1e-06 26.7 0.1 0.035 12.7 0.0 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GBG69637.1 - 0.056 13.7 0.1 4.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GBG69637.1 - 0.14 12.7 1.7 38 4.9 0.2 3.3 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.32 GBG69638.1 - 5.7e-16 58.6 11.0 9.9e-07 29.4 0.1 5.1 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 GBG69638.1 - 2.1e-06 26.7 0.1 0.036 12.7 0.0 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GBG69638.1 - 0.057 13.7 0.1 4.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GBG69638.1 - 0.14 12.7 1.7 38 4.9 0.2 3.3 3 0 0 3 3 3 0 PQQ-like domain XS PF03468.14 GBG69639.1 - 1.6e-17 63.8 0.0 1.6e-17 63.8 0.0 2.8 2 1 2 4 4 4 1 XS domain zf-C3HC4_3 PF13920.6 GBG69639.1 - 0.36 10.7 10.2 2.1 8.2 10.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG69639.1 - 1.2 9.1 6.8 4.5 7.3 7.0 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Fez1 PF06818.15 GBG69639.1 - 1.8 9.0 50.4 0.18 12.2 7.6 2.3 2 0 0 2 2 2 0 Fez1 p450 PF00067.22 GBG69640.1 - 1.6e-87 294.2 0.0 2.2e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-CCHC PF00098.23 GBG69641.1 - 0.00031 20.7 0.5 0.00057 19.8 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF3584 PF12128.8 GBG69641.1 - 0.075 10.5 24.9 0.1 10.1 24.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Flagellin_N PF00669.20 GBG69641.1 - 0.39 10.8 3.3 0.22 11.6 0.3 2.0 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region DUF1664 PF07889.12 GBG69641.1 - 1.1 9.3 8.4 0.44 10.6 3.7 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 GBG69641.1 - 2.5 8.1 22.1 0.85 9.6 0.5 3.5 3 1 0 3 3 3 0 Prefoldin subunit DUF3915 PF13054.6 GBG69641.1 - 2.7 8.0 6.2 6 6.9 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Fzo_mitofusin PF04799.13 GBG69641.1 - 3.1 7.3 11.3 0.15 11.6 2.1 2.9 2 1 0 3 3 3 0 fzo-like conserved region RVT_1 PF00078.27 GBG69643.1 - 1.3e-27 96.8 0.0 3e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69643.1 - 1.5e-22 79.8 0.1 9.1e-22 77.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69643.1 - 5.4e-22 77.7 0.0 2.2e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG69643.1 - 9.2e-09 35.6 0.3 9.2e-09 35.6 0.3 3.2 3 0 0 3 3 2 1 Myb/SANT-like DNA-binding domain Asp_protease_2 PF13650.6 GBG69643.1 - 3.1e-08 34.2 0.0 9.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69643.1 - 1.2e-07 31.6 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG69643.1 - 2.4e-06 28.0 0.0 1.2e-05 25.8 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG69643.1 - 0.00027 21.0 0.0 0.00063 19.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG69643.1 - 0.0026 17.5 0.0 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG69643.1 - 0.0045 17.2 1.7 0.021 15.1 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein DUF2937 PF11157.8 GBG69643.1 - 0.015 15.1 1.2 0.043 13.5 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) AMP-binding PF00501.28 GBG69643.1 - 0.015 13.9 0.0 0.053 12.1 0.0 1.8 2 0 0 2 2 2 0 AMP-binding enzyme MADF_DNA_bdg PF10545.9 GBG69643.1 - 0.16 12.3 1.4 0.38 11.1 0.2 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CorA PF01544.18 GBG69643.1 - 0.18 11.1 0.4 0.83 8.9 0.0 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein COG5 PF10392.9 GBG69643.1 - 0.34 11.1 1.8 0.39 10.9 0.2 1.9 2 0 0 2 2 1 0 Golgi transport complex subunit 5 Spectrin PF00435.21 GBG69643.1 - 9.8 6.7 13.5 10 6.6 0.3 4.4 4 0 0 4 4 3 0 Spectrin repeat DDE_Tnp_4 PF13359.6 GBG69644.1 - 1.3e-33 115.9 0.0 2.3e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69644.1 - 2.2e-13 50.3 0.0 3.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG69644.1 - 0.0011 18.7 0.1 1 8.9 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG69644.1 - 0.071 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain AMP-binding PF00501.28 GBG69645.1 - 4.7e-48 163.8 0.0 1.3e-42 145.9 0.0 2.6 3 0 0 3 3 3 2 AMP-binding enzyme PQQ_3 PF13570.6 GBG69645.1 - 1.1e-24 86.2 8.6 3.2e-05 24.3 0.2 8.0 7 0 0 7 7 7 6 PQQ-like domain PQQ_2 PF13360.6 GBG69645.1 - 1.2e-14 54.4 0.0 2e-08 34.1 0.0 4.0 2 2 1 4 4 4 2 PQQ-like domain PQQ PF01011.21 GBG69645.1 - 8.6e-14 50.7 1.5 0.00079 19.2 0.0 5.7 5 1 0 5 5 5 3 PQQ enzyme repeat AMP-binding_C PF13193.6 GBG69645.1 - 0.00017 22.5 8.7 0.00018 22.4 0.0 3.2 3 0 0 3 3 2 1 AMP-binding enzyme C-terminal domain DUF1676 PF07898.13 GBG69645.1 - 0.0038 17.3 1.2 0.01 15.9 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) DUF1129 PF06570.11 GBG69645.1 - 0.036 13.5 3.5 0.063 12.8 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Cation_ATPase_C PF00689.21 GBG69645.1 - 0.091 12.5 0.3 0.16 11.7 0.3 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Orf78 PF06024.12 GBG69645.1 - 0.11 12.7 3.4 0.27 11.6 3.4 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF3784 PF12650.7 GBG69645.1 - 0.13 12.5 1.0 0.27 11.4 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Shisa PF13908.6 GBG69645.1 - 0.35 11.1 3.4 0.92 9.7 2.8 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator CrgA PF06781.12 GBG69645.1 - 0.65 10.1 5.4 1.9 8.6 5.4 1.7 1 0 0 1 1 1 0 Cell division protein CrgA LAP1C PF05609.12 GBG69645.1 - 5.8 5.9 7.5 0.32 10.0 1.1 1.9 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) ATP-synt PF00231.19 GBG69647.1 - 6.4e-75 252.4 3.6 8.6e-75 252.0 3.6 1.2 1 0 0 1 1 1 1 ATP synthase GDPD PF03009.17 GBG69647.1 - 9.2e-67 225.5 0.0 1.3e-45 156.2 0.0 2.4 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family CTP_transf_like PF01467.26 GBG69647.1 - 4.3e-06 27.0 0.0 9.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like KRAB PF01352.27 GBG69647.1 - 0.041 13.6 0.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 KRAB box SCVP PF17619.2 GBG69647.1 - 0.16 12.8 0.6 61 4.6 0.0 3.3 3 0 0 3 3 3 0 Secreted clade V proteins FAD_syn PF06574.12 GBG69647.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase ARPC4 PF05856.12 GBG69648.1 - 2.3e-74 248.6 5.3 2.6e-74 248.4 5.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Osmo_CC PF08946.10 GBG69648.1 - 0.072 13.4 0.2 0.18 12.1 0.2 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil SMC_Nse1 PF07574.13 GBG69649.1 - 1.8e-27 96.5 0.0 1.8e-27 96.5 0.0 2.8 3 0 0 3 3 3 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 GBG69649.1 - 1.3e-08 35.0 8.8 2.5e-08 34.1 8.8 1.5 1 0 0 1 1 1 1 RING-like domain KASH_CCD PF14662.6 GBG69649.1 - 0.0075 16.1 4.8 0.0075 16.1 4.8 2.8 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH Bmp PF02608.14 GBG69649.1 - 0.084 11.8 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like zf-ANAPC11 PF12861.7 GBG69649.1 - 0.11 12.6 1.9 0.21 11.7 1.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1018 PF06252.12 GBG69649.1 - 0.12 13.4 12.0 0.31 12.0 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) zf-RING_2 PF13639.6 GBG69649.1 - 0.46 10.9 6.6 0.8 10.1 6.6 1.4 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 GBG69649.1 - 0.93 9.4 7.1 2.2 8.3 7.1 1.7 1 0 0 1 1 1 0 PHD-finger YlqD PF11068.8 GBG69649.1 - 3.3 8.1 14.9 0.08 13.3 5.9 2.5 1 1 1 2 2 2 0 YlqD protein TipAS PF07739.13 GBG69649.1 - 4.8 7.7 9.8 5.4 7.6 5.4 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Afi1 PF07792.12 GBG69649.1 - 9 6.8 14.1 3.7 8.0 7.5 2.9 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking GYF_2 PF14237.6 GBG69650.1 - 2e-15 56.3 0.2 5.1e-15 55.0 0.2 1.8 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 GBG69650.1 - 5.3e-11 42.5 0.2 1.2e-10 41.3 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Drf_GBD PF06371.13 GBG69650.1 - 0.052 13.1 0.1 0.86 9.1 0.0 2.3 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain tRNA-synt_1 PF00133.22 GBG69651.1 - 3.3e-29 101.6 0.0 5e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Na_trans_assoc PF06512.13 GBG69651.1 - 0.34 11.2 9.6 0.46 10.7 9.6 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG69651.1 - 2.2 7.6 22.5 3 7.2 22.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG69651.1 - 2.6 6.1 19.6 3.3 5.8 19.6 1.1 1 0 0 1 1 1 0 Nop14-like family Citrate_synt PF00285.21 GBG69652.1 - 1.5e-135 452.0 0.0 1.8e-135 451.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain tRNA-synt_1 PF00133.22 GBG69653.1 - 1.2e-49 169.1 0.1 1.6e-49 168.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GBG69653.1 - 5.7e-07 28.6 0.0 8.4e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) UDPGP PF01704.18 GBG69654.1 - 7e-161 535.5 0.0 2.4e-159 530.4 0.0 2.0 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Tyrosinase PF00264.20 GBG69655.1 - 9.3e-33 114.4 13.0 7.7e-17 62.3 0.6 3.1 2 1 1 3 3 3 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG69655.1 - 4.9e-12 45.4 0.3 9.8e-12 44.5 0.3 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain CAP_N PF01213.19 GBG69655.1 - 0.0042 16.6 9.1 0.011 15.2 9.1 1.7 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Lin-8 PF03353.15 GBG69655.1 - 0.5 9.9 12.1 0.8 9.2 12.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mito_fiss_reg PF05308.11 GBG69655.1 - 2.5 8.1 15.7 9.3 6.3 14.5 2.3 1 1 0 2 2 2 0 Mitochondrial fission regulator DUF659 PF04937.15 GBG69656.1 - 1.5e-14 54.1 0.0 2.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GCHY-1 PF02649.14 GBG69656.1 - 0.24 10.9 0.0 0.41 10.1 0.0 1.3 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 zf-CCHC PF00098.23 GBG69657.1 - 4.3e-07 29.7 2.0 4.3e-07 29.7 2.0 1.7 2 0 0 2 2 2 1 Zinc knuckle Spc7 PF08317.11 GBG69657.1 - 0.12 11.2 11.8 0.16 10.8 11.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-CCHC_4 PF14392.6 GBG69657.1 - 0.2 11.4 0.6 0.41 10.4 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle RRN3 PF05327.11 GBG69657.1 - 0.27 9.7 2.7 0.32 9.5 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LMBR1 PF04791.16 GBG69657.1 - 0.3 9.9 4.9 0.35 9.7 4.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Bud13 PF09736.9 GBG69657.1 - 0.44 10.9 11.4 0.93 9.9 11.4 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Phage_Gp23 PF10669.9 GBG69657.1 - 1 9.7 11.9 1.5 9.2 11.9 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Casc1_N PF15927.5 GBG69657.1 - 1.3 8.7 18.6 2.6 7.7 18.6 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Presenilin PF01080.17 GBG69657.1 - 5.9 5.5 4.5 6.4 5.4 4.5 1.1 1 0 0 1 1 1 0 Presenilin GvpL_GvpF PF06386.11 GBG69657.1 - 9.5 6.1 10.8 8.3 6.3 9.6 1.3 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TP_methylase PF00590.20 GBG69658.1 - 5.3e-46 157.2 0.1 8.2e-46 156.6 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases EF-hand_6 PF13405.6 GBG69659.1 - 8.4e-10 37.8 1.8 0.00036 20.2 0.8 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GBG69659.1 - 2.1e-09 37.7 0.5 3.2e-09 37.1 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GBG69659.1 - 1.3e-08 33.8 2.9 6.2e-05 22.3 2.7 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GBG69659.1 - 4.8e-05 23.1 0.8 0.00014 21.7 0.5 2.0 1 1 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GBG69659.1 - 0.0011 19.2 0.2 0.024 15.0 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 GBG69659.1 - 0.0013 18.2 3.9 0.011 15.1 1.2 2.4 2 0 0 2 2 2 1 EF hand DndB PF14072.6 GBG69659.1 - 0.14 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 DNA-sulfur modification-associated RVT_1 PF00078.27 GBG69660.1 - 6.6e-15 55.2 0.0 8.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG69661.1 - 0.047 14.0 3.1 0.1 12.9 0.0 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein EF-hand_7 PF13499.6 GBG69663.1 - 6.6e-12 45.7 0.9 1e-11 45.1 0.9 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GBG69663.1 - 1.1e-09 37.2 3.7 1.3e-05 24.4 1.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GBG69663.1 - 7.1e-09 34.9 2.2 0.0012 18.6 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GBG69663.1 - 0.00027 20.7 0.5 0.00087 19.1 0.5 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GBG69663.1 - 0.0044 16.5 4.4 0.024 14.1 0.6 2.5 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 GBG69663.1 - 0.0062 16.9 1.0 0.15 12.4 0.9 2.1 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GBG69663.1 - 0.066 13.2 1.2 0.4 10.7 1.0 2.0 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand GPAT_N PF14829.6 GBG69664.1 - 4.7e-18 64.9 0.0 1.2e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase N-terminal Acyltransferase PF01553.21 GBG69664.1 - 4.2e-14 52.3 0.0 7.6e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase RT_RNaseH_2 PF17919.1 GBG69665.1 - 1.3e-16 60.5 0.0 2.5e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69665.1 - 6.8e-10 38.8 1.1 7.1e-10 38.8 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69665.1 - 4e-06 27.1 0.0 8.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase OGG_N PF07934.12 GBG69665.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain RWP-RK PF02042.15 GBG69666.1 - 4.3e-22 77.8 0.5 9.1e-22 76.8 0.5 1.5 1 0 0 1 1 1 1 RWP-RK domain DUF4680 PF15730.5 GBG69666.1 - 0.006 16.9 0.8 0.025 14.9 0.8 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4680) Tyrosinase PF00264.20 GBG69667.1 - 3.8e-27 96.0 10.8 2.3e-14 54.2 0.2 2.5 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG69667.1 - 4.8e-07 29.5 0.1 1.2e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Polyphenol oxidase middle domain Pectinesterase PF01095.19 GBG69668.1 - 2.2e-84 282.7 1.6 3e-84 282.3 1.6 1.1 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.15 GBG69668.1 - 1.2e-05 25.7 2.2 2.1e-05 24.9 2.2 1.4 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor PBP_like_2 PF12849.7 GBG69668.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain Nop53 PF07767.11 GBG69669.1 - 0.02 14.3 16.9 0.022 14.2 16.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PPP4R2 PF09184.11 GBG69669.1 - 0.061 12.9 13.6 0.063 12.9 13.6 1.2 1 0 0 1 1 1 0 PPP4R2 Na_trans_assoc PF06512.13 GBG69669.1 - 0.085 13.1 13.7 0.1 12.9 13.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Neur_chan_memb PF02932.16 GBG69669.1 - 0.96 9.5 3.2 1.1 9.3 3.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 GBG69669.1 - 3.5 6.3 7.4 4.2 6.1 7.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cwf_Cwc_15 PF04889.12 GBG69669.1 - 4.7 6.9 22.1 5.7 6.6 22.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG69669.1 - 6.4 4.8 27.8 7.8 4.6 27.8 1.0 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG69670.1 - 3.2e-29 100.9 0.0 5.2e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69670.1 - 5.1e-29 100.7 0.0 8.2e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69670.1 - 1e-14 54.6 0.1 1.5e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG69670.1 - 0.032 14.1 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Acetyltransf_1 PF00583.25 GBG69671.1 - 2.6e-07 30.9 0.0 1.9e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GBG69671.1 - 1.8e-05 24.7 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG69671.1 - 4.4e-05 23.4 0.0 7.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 GBG69671.1 - 0.00036 20.9 0.0 0.00063 20.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BUD22 PF09073.10 GBG69671.1 - 0.089 12.1 39.6 0.29 10.4 33.8 2.1 2 0 0 2 2 2 0 BUD22 Pox_Ag35 PF03286.14 GBG69671.1 - 0.61 9.8 0.0 0.61 9.8 0.0 3.3 2 1 0 2 2 2 0 Pox virus Ag35 surface protein Tub_N PF16322.5 GBG69671.1 - 1.4 9.3 27.0 6.7 7.1 0.9 2.2 2 0 0 2 2 2 0 Tubby N-terminal Na_trans_assoc PF06512.13 GBG69671.1 - 2.5 8.3 22.0 13 6.0 0.1 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated CDC27 PF09507.10 GBG69671.1 - 3.2 7.0 28.9 0.29 10.5 21.9 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Methyltransf_3 PF01596.17 GBG69672.1 - 7.2e-22 77.6 0.0 1.3e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GBG69672.1 - 0.00028 21.9 0.0 0.00088 20.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GBG69672.1 - 0.011 15.6 0.0 0.036 14.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain NFACT-R_2 PF18297.1 GBG69672.1 - 0.04 14.1 0.4 0.32 11.2 0.2 2.4 2 1 0 2 2 2 0 NFACT protein RNA binding domain GTSE1_N PF15259.6 GBG69672.1 - 0.87 9.8 7.3 0.069 13.3 2.1 1.8 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Methyltransf_3 PF01596.17 GBG69673.1 - 1.7e-08 33.9 0.0 3.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Exostosin PF03016.15 GBG69674.1 - 2.2e-68 230.7 0.0 3e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Exostosin family DUF4611 PF15387.6 GBG69674.1 - 0.015 15.5 6.7 0.034 14.4 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 GBG69674.1 - 3.3 6.9 9.7 5.1 6.3 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GBG69674.1 - 3.6 7.2 4.4 7.2 6.3 4.4 1.4 1 0 0 1 1 1 0 FAM176 family Exostosin PF03016.15 GBG69675.1 - 2.3e-68 230.6 0.0 3.2e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Exostosin family DUF4611 PF15387.6 GBG69675.1 - 0.019 15.2 6.9 0.042 14.1 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 GBG69675.1 - 1.9 7.7 8.3 2.9 7.1 8.3 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GBG69675.1 - 5.3 6.7 4.8 11 5.7 4.8 1.4 1 0 0 1 1 1 0 FAM176 family BES1_N PF05687.13 GBG69676.1 - 5.7e-11 43.0 0.6 7.7e-11 42.6 0.5 1.3 1 1 0 1 1 1 1 BES1/BZR1 plant transcription factor, N-terminal HLH PF00010.26 GBG69676.1 - 0.079 12.9 3.7 0.17 11.9 3.7 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Retrotrans_gag PF03732.17 GBG69677.1 - 0.038 14.3 0.1 0.038 14.3 0.1 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein GIY-YIG PF01541.24 GBG69678.1 - 0.0052 17.0 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain DDE_Tnp_4 PF13359.6 GBG69681.1 - 1.7e-31 109.0 0.0 3e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69681.1 - 1.4e-14 54.2 0.0 2.5e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG69681.1 - 0.038 13.6 0.0 7 6.2 0.1 2.6 2 0 0 2 2 2 0 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG69682.1 - 1.3e-30 105.4 0.0 2.6e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69682.1 - 2.2e-30 105.0 0.0 4.9e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69682.1 - 9.5e-26 90.7 0.0 1.6e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG69682.1 - 1.7e-15 56.8 0.1 3.8e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG69682.1 - 1.3e-05 25.3 0.0 3.7e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger LEA_2 PF03168.13 GBG69684.1 - 4.9e-09 36.6 0.3 6.7e-09 36.2 0.3 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein Myb_DNA-bind_4 PF13837.6 GBG69687.1 - 8.1e-09 35.7 0.4 1.4e-08 35.0 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG69687.1 - 0.038 14.2 0.1 0.067 13.4 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG69687.1 - 0.039 14.3 0.3 0.072 13.4 0.3 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TFIIA PF03153.13 GBG69690.1 - 0.12 12.4 5.7 0.12 12.3 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 GBG69690.1 - 7.2 5.8 15.2 9.4 5.5 15.2 1.1 1 0 0 1 1 1 0 BUD22 RPA43_OB PF17875.1 GBG69690.1 - 7.8 7.1 7.1 16 6.2 7.1 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I TK PF00265.18 GBG69691.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Thymidine kinase DUF659 PF04937.15 GBG69692.1 - 3.5e-16 59.4 0.0 6.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG69692.1 - 7.7e-05 22.4 0.3 0.00017 21.3 0.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SprA-related PF12118.8 GBG69692.1 - 0.0033 16.6 23.9 0.0033 16.6 23.9 2.0 2 0 0 2 2 2 1 SprA-related family MMR1 PF08505.10 GBG69692.1 - 0.026 14.8 14.5 0.051 13.9 14.5 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF3464 PF11947.8 GBG69692.1 - 0.51 10.1 0.0 0.51 10.1 0.0 3.6 2 1 1 3 3 3 0 Photosynthesis affected mutant 68 DUF726 PF05277.12 GBG69692.1 - 1.1 8.1 4.2 1.9 7.3 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PAT1 PF09770.9 GBG69692.1 - 2.1 6.5 22.5 4 5.6 22.5 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HU-CCDC81_bac_2 PF18175.1 GBG69695.1 - 1.4 8.9 6.0 8.6 6.3 2.7 3.5 4 0 0 4 4 4 0 CCDC81-like prokaryotic HU domain 2 RT_RNaseH_2 PF17919.1 GBG69696.1 - 4.4e-28 97.2 0.0 1.2e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69696.1 - 3e-23 82.1 0.0 7.8e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG69696.1 - 2e-07 30.9 0.0 5.2e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69696.1 - 3.8e-06 27.5 0.0 9.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69696.1 - 0.00026 21.5 0.4 0.0012 19.3 0.0 2.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG69696.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG69696.1 - 0.0045 16.8 0.1 0.015 15.1 0.1 1.8 1 1 0 1 1 1 1 Aspartyl protease DUF5600 PF18150.1 GBG69696.1 - 0.47 11.0 6.3 0.33 11.5 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) Integrase_H2C2 PF17921.1 GBG69697.1 - 2e-29 101.4 1.7 8.9e-18 64.2 0.6 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG69697.1 - 3.3e-29 100.8 0.0 6.2e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69697.1 - 7.5e-29 100.1 0.0 1.6e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69697.1 - 4.9e-25 88.0 0.0 4.2e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG69697.1 - 6.1e-05 23.1 1.9 0.0022 18.2 0.1 3.7 4 0 0 4 4 4 1 H2C2 zinc finger RVT_1 PF00078.27 GBG69697.1 - 0.00023 20.8 0.2 0.00044 19.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG69697.1 - 0.15 11.9 0.0 0.5 10.2 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Asp_protease_2 PF13650.6 GBG69698.1 - 2.7e-06 27.9 0.0 1.2e-05 25.9 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69698.1 - 2.2e-05 24.9 0.0 4.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG69698.1 - 0.00073 19.8 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG69699.1 - 5.3e-23 81.7 0.1 1.4e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69699.1 - 4e-14 52.8 0.0 8.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG69699.1 - 0.015 15.5 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Fimbrial PF00419.20 GBG69700.1 - 0.05 13.9 0.1 0.05 13.9 0.1 1.1 1 0 0 1 1 1 0 Fimbrial protein DivIC PF04977.15 GBG69701.1 - 0.012 15.3 2.4 0.012 15.3 2.4 3.1 2 1 0 2 2 2 0 Septum formation initiator BORCS8 PF10167.9 GBG69701.1 - 0.083 12.8 0.5 0.21 11.5 0.5 1.7 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 zf-CCHC PF00098.23 GBG69701.1 - 0.12 12.5 0.5 0.25 11.5 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Prominin PF05478.11 GBG69701.1 - 0.19 9.7 0.6 0.25 9.2 0.6 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 GBG69701.1 - 1.6 8.8 6.1 8 6.5 2.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 GBG69701.1 - 9.1 6.0 9.7 3 7.6 1.4 3.1 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain ATG16 PF08614.11 GBG69701.1 - 9.2 6.4 27.0 0.045 14.0 9.4 3.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Glyco_transf_20 PF00982.21 GBG69703.1 - 2.1e-175 584.0 0.0 6.8e-128 427.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GBG69703.1 - 1.6e-33 115.8 0.0 1.6e-32 112.5 0.0 2.1 1 1 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 GBG69703.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 GBG69703.1 - 0.29 11.5 2.0 0.68 10.4 2.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 GBG69704.1 - 1.2e-182 607.9 0.0 1.5e-182 607.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GBG69704.1 - 3.8e-39 134.2 0.0 6.4e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 GBG69704.1 - 0.061 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 GBG69704.1 - 0.062 13.7 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Importin_rep_4 PF18808.1 GBG69706.1 - 8.2e-05 22.8 1.5 0.51 10.6 0.1 3.0 1 1 3 4 4 4 2 Importin repeat Shugoshin_C PF07557.11 GBG69706.1 - 0.0035 17.1 3.5 5.1 7.0 0.0 4.2 4 0 0 4 4 4 2 Shugoshin C terminus FCH PF00611.23 GBG69706.1 - 0.011 16.0 0.5 0.62 10.4 0.1 2.8 2 1 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain Albumin_I_a PF16720.5 GBG69706.1 - 0.021 14.8 2.6 41 4.2 0.0 4.1 3 3 1 4 4 4 0 Albumin I chain a PHB_acc PF05233.13 GBG69706.1 - 0.032 14.3 0.0 7.8 6.6 0.0 3.1 3 1 0 3 3 3 0 PHB accumulation regulatory domain DHR-2 PF06920.13 GBG69706.1 - 0.045 12.4 1.5 0.17 10.5 0.7 1.8 1 1 1 2 2 2 0 Dock homology region 2 F_actin_bind PF08919.10 GBG69706.1 - 0.046 13.8 1.5 0.25 11.5 0.5 2.5 1 1 2 3 3 3 0 F-actin binding ERp29 PF07749.12 GBG69706.1 - 0.14 13.1 0.7 4.2 8.3 0.2 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain LEAP-2 PF07359.11 GBG69706.1 - 0.15 11.9 1.3 31 4.5 0.0 3.0 3 0 0 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) FATC PF02260.20 GBG69706.1 - 0.22 11.3 4.1 1.2e+02 2.6 0.1 4.6 5 0 0 5 5 5 0 FATC domain GDNF PF02351.16 GBG69706.1 - 0.78 10.8 6.6 4.5 8.3 1.8 2.3 1 1 1 2 2 2 0 GDNF/GAS1 domain Bee_toxin PF17454.2 GBG69706.1 - 1.9 8.6 6.8 16 5.6 0.1 3.1 3 0 0 3 3 3 0 Honey bee toxin DUF4820 PF16091.5 GBG69707.1 - 2.5 7.4 8.3 2.7 7.3 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Integrase_H2C2 PF17921.1 GBG69708.1 - 1.9e-16 59.9 2.0 4.8e-16 58.6 2.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG69708.1 - 0.14 12.1 0.3 0.32 11.0 0.3 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG69708.1 - 0.19 12.1 1.9 1.2 9.5 0.4 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG69710.1 - 1.2e-25 90.4 0.2 1.9e-25 89.7 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69710.1 - 3.8e-12 46.1 0.0 9.8e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69710.1 - 2.9e-05 24.3 0.0 6.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG69710.1 - 0.018 15.3 4.1 0.025 14.9 0.1 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG69711.1 - 0.0046 17.6 0.0 0.016 15.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG69711.1 - 0.0048 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG69711.1 - 0.0077 16.8 0.0 0.026 15.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG69711.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease tRNA_Me_trans PF03054.16 GBG69711.1 - 0.097 11.4 1.2 0.82 8.4 1.7 2.1 2 0 0 2 2 2 0 tRNA methyl transferase RVT_1 PF00078.27 GBG69712.1 - 3.7e-30 105.1 0.7 6.8e-30 104.2 0.7 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG69712.1 - 0.028 15.0 0.0 0.09 13.4 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG69712.1 - 0.034 14.7 0.0 0.084 13.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG69713.1 - 3e-32 110.6 0.0 7.3e-32 109.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69713.1 - 5.1e-31 107.9 0.1 1e-30 106.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69713.1 - 1.6e-30 105.5 0.1 3.4e-30 104.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69713.1 - 9.2e-16 57.7 0.0 2.3e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69713.1 - 6.4e-15 55.4 0.0 2.2e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG69713.1 - 0.049 13.9 0.0 0.65 10.3 0.0 2.6 2 0 0 2 2 2 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG69714.1 - 1.1e-05 25.6 1.2 0.00037 20.7 0.0 3.2 3 0 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG69714.1 - 0.00033 20.2 0.0 0.00079 19.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_24 PF13479.6 GBG69714.1 - 0.0086 15.8 1.0 0.052 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF4187 PF13821.6 GBG69714.1 - 0.29 10.9 8.5 0.03 14.1 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Nbs1_C PF08599.10 GBG69714.1 - 6.9 6.9 7.0 30 4.9 7.0 2.1 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 Sec16_C PF12931.7 GBG69715.1 - 5.4e-12 46.0 1.2 3.6e-11 43.3 1.2 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 GBG69715.1 - 3.7e-06 26.8 0.0 4.5e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 GBG69715.1 - 0.00012 22.8 8.7 1.9 9.5 0.3 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat Sec16 PF12932.7 GBG69715.1 - 0.13 12.9 0.0 0.4 11.3 0.0 1.8 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region rve PF00665.26 GBG69717.1 - 6.1e-07 29.7 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain FAT PF02259.23 GBG69718.1 - 0.01 15.1 0.5 0.018 14.2 0.0 1.6 2 0 0 2 2 2 0 FAT domain Retrotrans_gag PF03732.17 GBG69718.1 - 0.069 13.4 6.3 0.084 13.2 0.0 3.8 6 0 0 6 6 6 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG69721.1 - 1.5e-27 95.5 0.1 2.7e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69721.1 - 6.8e-23 81.0 0.2 1.2e-22 80.2 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69721.1 - 0.00078 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG69722.1 - 4.3e-74 248.8 0.4 2.8e-26 92.4 0.1 3.6 4 0 0 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69722.1 - 1.3e-13 50.8 0.0 4.1e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69722.1 - 9.2e-10 38.8 0.0 3.9e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG69722.1 - 1.7e-09 37.6 0.0 0.00055 19.7 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69722.1 - 2.5e-06 28.1 0.0 2.4e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69722.1 - 2.8e-06 27.8 0.0 9.6e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG69722.1 - 1.6e-05 25.1 0.0 4.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG69722.1 - 0.00023 20.9 0.0 0.00055 19.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG69722.1 - 0.0012 19.1 0.6 0.88 9.9 0.0 3.8 4 0 0 4 4 4 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG69723.1 - 3.5e-50 170.6 0.6 4.5e-27 95.0 0.1 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69723.1 - 3e-14 52.9 0.0 8.8e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69723.1 - 4.7e-06 26.8 0.0 9.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG69723.1 - 0.0022 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Trans_reg_C PF00486.28 GBG69723.1 - 0.066 13.3 1.2 3.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal VirDNA-topo-I_N PF09266.10 GBG69723.1 - 0.12 12.5 1.2 23 5.2 0.1 2.7 3 0 0 3 3 3 0 Viral DNA topoisomerase I, N-terminal DUF2313 PF10076.9 GBG69723.1 - 0.21 11.4 0.0 2.6 7.9 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2313) Retrotrans_gag PF03732.17 GBG69724.1 - 0.017 15.4 0.0 0.1 12.9 0.0 2.4 1 0 0 1 1 1 0 Retrotransposon gag protein SlyX PF04102.12 GBG69724.1 - 0.029 15.0 1.2 0.029 15.0 1.2 4.1 3 1 1 4 4 4 0 SlyX TRPM_tetra PF16519.5 GBG69724.1 - 0.11 12.6 3.5 2 8.6 0.1 3.4 3 1 1 4 4 4 0 Tetramerisation domain of TRPM PTS_IIA PF02255.16 GBG69724.1 - 4 7.6 10.2 4 7.6 2.0 3.1 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit RVT_1 PF00078.27 GBG69725.1 - 2.6e-29 102.4 0.1 4.1e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69725.1 - 1.2e-18 67.0 0.0 2.4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69725.1 - 2e-17 63.0 1.5 4.1e-17 62.0 1.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG69725.1 - 1.4e-10 41.4 0.0 4e-08 33.5 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG69725.1 - 7.7e-08 32.8 0.0 1.5e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69725.1 - 7.7e-07 29.7 0.0 1.8e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG69725.1 - 1.8e-05 24.9 0.0 4.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG69725.1 - 2.6e-05 24.0 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69725.1 - 0.00014 21.6 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG69725.1 - 0.012 15.8 0.2 0.032 14.4 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG69726.1 - 2.5e-15 56.3 0.1 5e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG69726.1 - 0.0049 17.1 0.0 0.0096 16.1 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Complex1_51K PF01512.17 GBG69727.1 - 4.1e-47 159.9 0.0 6.9e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 GBG69727.1 - 1.5e-29 101.9 0.0 2.8e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 GBG69727.1 - 5.1e-08 32.7 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 SLBB domain CCDC53 PF10152.9 GBG69727.1 - 4.5 7.7 5.0 2.5 8.5 3.0 1.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RT_RNaseH_2 PF17919.1 GBG69728.1 - 1.4e-13 50.7 0.0 2.9e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69728.1 - 8.2e-11 42.1 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG69728.1 - 0.0014 19.1 0.1 0.0035 17.9 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG69728.1 - 0.013 15.8 0.1 0.069 13.5 0.1 2.2 2 1 1 3 3 3 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69728.1 - 0.026 15.2 0.1 0.084 13.5 0.1 1.9 1 0 0 1 1 1 0 Aspartyl protease PLAC9 PF15205.6 GBG69728.1 - 0.029 14.8 0.1 0.096 13.1 0.0 1.9 2 0 0 2 2 2 0 Placenta-specific protein 9 Asp_protease PF09668.10 GBG69728.1 - 0.19 11.5 0.2 0.57 10.0 0.1 1.8 2 0 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.27 GBG69729.1 - 6.3e-27 94.5 0.1 9.6e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69729.1 - 2.5e-08 34.1 0.0 5.9e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG69729.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG69731.1 - 3.4e-29 101.2 0.0 6.8e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69731.1 - 3.4e-28 97.6 0.0 6.6e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69731.1 - 5.5e-20 71.2 0.5 1.2e-19 70.2 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69731.1 - 4e-05 23.8 0.0 0.00013 22.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG69731.1 - 0.00011 21.8 0.1 0.00023 20.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG69731.1 - 0.00039 20.6 0.1 0.0012 19.1 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger SbcD_C PF12320.8 GBG69731.1 - 0.026 14.8 0.3 5 7.5 0.0 2.4 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Phage_GPO PF05929.11 GBG69731.1 - 0.13 11.8 0.2 0.26 10.9 0.0 1.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4392 PF14336.6 GBG69731.1 - 0.24 10.8 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) RVT_1 PF00078.27 GBG69732.1 - 2.6e-09 36.9 0.0 4.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG69732.1 - 1.3e-05 25.7 0.0 3.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69732.1 - 2.3e-05 24.2 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG69732.1 - 0.0013 19.2 0.1 0.0062 17.1 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG69732.1 - 0.032 14.0 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG69732.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG69733.1 - 4.4e-24 85.2 1.0 7.5e-24 84.5 0.2 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69733.1 - 2.4e-23 82.1 0.0 4.5e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69733.1 - 2.2e-22 79.3 0.2 4.2e-22 78.4 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG69734.1 - 6e-07 29.3 0.0 2e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69734.1 - 7.8e-07 29.7 0.0 2.3e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69734.1 - 2.6e-05 24.7 0.0 0.00011 22.7 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG69734.1 - 0.00014 21.4 0.5 0.0064 16.0 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG69734.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG69734.1 - 0.021 15.1 0.0 0.068 13.5 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein AMP-binding_C_2 PF14535.6 GBG69734.1 - 0.024 14.9 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain SlyX PF04102.12 GBG69734.1 - 0.068 13.8 4.7 0.96 10.1 0.2 3.4 3 1 0 3 3 3 0 SlyX rve PF00665.26 GBG69735.1 - 2.3e-10 40.7 0.0 4.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG69735.1 - 2e-05 24.4 0.0 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG69735.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG69736.1 - 2.2e-09 37.2 0.2 4.5e-09 36.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG69736.1 - 5e-07 30.2 0.0 1.6e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG69736.1 - 1.1e-06 28.4 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69736.1 - 1.4e-06 28.8 0.0 4e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG69736.1 - 1.7e-05 24.6 0.0 4.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG69736.1 - 0.14 12.5 0.4 0.35 11.2 0.4 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein rve PF00665.26 GBG69737.1 - 2.9e-13 50.1 0.0 5.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG69737.1 - 1.9e-11 43.9 0.0 4.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG69737.1 - 0.0015 19.0 0.0 0.0043 17.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG69737.1 - 0.005 17.1 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 GBG69737.1 - 0.0063 16.3 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG69737.1 - 0.0098 15.7 0.8 0.021 14.6 0.1 1.8 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG69737.1 - 0.1 13.3 0.0 0.5 11.1 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease DUF659 PF04937.15 GBG69738.1 - 3.1e-32 111.6 0.1 3.1e-32 111.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG69739.1 - 1.7e-21 76.5 0.0 4.2e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69739.1 - 8.5e-21 73.9 0.0 1.8e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69739.1 - 1.9e-19 70.1 0.0 7e-19 68.2 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69739.1 - 2.9e-08 33.9 0.0 1.1e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG69739.1 - 2.1e-07 30.8 0.0 4.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69739.1 - 4.1e-06 27.3 0.0 1.5e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69739.1 - 0.00012 22.5 0.1 0.00049 20.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG69739.1 - 0.021 14.6 0.0 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 Aspartyl protease DUF4187 PF13821.6 GBG69739.1 - 0.068 13.0 0.4 0.22 11.3 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RT_RNaseH_2 PF17919.1 GBG69740.1 - 1.8e-23 82.5 0.0 3.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69740.1 - 5.8e-17 61.9 0.0 1.1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69740.1 - 1.6e-06 27.8 0.1 2.4e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69740.1 - 1.6e-06 28.3 0.1 3.9e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG69740.1 - 4.3e-05 23.3 0.0 8.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 GBG69741.1 - 0.26 11.4 4.7 0.43 10.8 4.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG69741.1 - 0.66 10.0 3.2 1.3 9.0 3.2 1.4 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 GBG69742.1 - 8.2e-14 51.8 0.1 2.1e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG69742.1 - 0.17 11.7 0.9 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG69743.1 - 3.3e-23 81.6 0.0 6.7e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69743.1 - 1.7e-21 76.5 0.0 6.5e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69743.1 - 2e-13 50.2 0.0 5.8e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69743.1 - 2.6e-13 50.2 0.0 1e-12 48.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG69743.1 - 0.013 15.3 0.0 0.038 13.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain CD99L2 PF12301.8 GBG69743.1 - 0.22 11.8 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 Retrotrans_gag PF03732.17 GBG69744.1 - 0.0027 18.0 0.3 0.12 12.6 0.0 3.6 4 0 0 4 4 4 1 Retrotransposon gag protein Filament PF00038.21 GBG69744.1 - 5.3 6.5 12.4 1.6 8.3 4.7 2.6 2 1 0 2 2 2 0 Intermediate filament protein RT_RNaseH_2 PF17919.1 GBG69746.1 - 2.6e-25 88.4 0.0 5.9e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69746.1 - 3.7e-23 81.8 0.0 1.2e-22 80.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69746.1 - 1.2e-14 54.5 0.0 2.9e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG69746.1 - 1.7e-11 44.1 0.0 4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG69746.1 - 0.00041 19.9 0.0 0.00072 19.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG69746.1 - 0.0033 17.2 0.0 0.013 15.2 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG69747.1 - 2.2e-22 79.3 0.0 4.9e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69747.1 - 1.3e-20 73.3 0.0 2.3e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69747.1 - 1.1e-08 35.3 0.0 2.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG69747.1 - 0.0055 16.5 0.0 0.02 14.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain alpha-hel2 PF14456.6 GBG69747.1 - 0.12 11.7 0.5 0.28 10.5 0.5 1.6 1 0 0 1 1 1 0 Alpha-helical domain 2 RVT_1 PF00078.27 GBG69748.1 - 7.2e-24 84.5 0.1 2.3e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG69748.1 - 1e-05 25.7 0.2 0.00073 19.8 0.1 3.3 2 0 0 2 2 2 1 Retrotransposon gag protein AIP3 PF03915.13 GBG69748.1 - 0.002 17.3 1.4 1.2 8.1 0.2 2.5 2 0 0 2 2 2 2 Actin interacting protein 3 Inhibitor_I29 PF08246.12 GBG69748.1 - 0.021 15.2 0.7 4.3 7.9 0.2 2.7 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) TRPM_tetra PF16519.5 GBG69748.1 - 0.052 13.6 1.2 7.5 6.7 0.1 2.9 2 0 0 2 2 2 0 Tetramerisation domain of TRPM YPEB PF14620.6 GBG69748.1 - 0.063 12.6 0.6 1.4 8.1 0.1 2.4 2 0 0 2 2 2 0 YpeB sporulation DUF2781 PF10914.8 GBG69748.1 - 0.065 13.6 0.1 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) FUSC PF04632.12 GBG69748.1 - 0.24 9.9 11.5 0.56 8.7 3.2 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family ZapB PF06005.12 GBG69748.1 - 0.33 11.4 9.1 1.1 9.8 0.1 4.6 4 2 0 4 4 3 0 Cell division protein ZapB GIT_CC PF16559.5 GBG69748.1 - 0.43 10.5 4.4 28 4.7 0.1 3.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor LPP PF04728.13 GBG69748.1 - 0.59 10.6 3.0 17 5.9 0.1 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper NPV_P10 PF05531.12 GBG69748.1 - 0.71 10.4 3.9 9.6 6.8 0.2 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 GBG69748.1 - 1 9.8 14.5 0.52 10.7 0.4 4.9 4 2 2 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RVT_1 PF00078.27 GBG69749.1 - 8.1e-35 120.3 0.1 1.3e-34 119.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69749.1 - 7.8e-22 77.2 0.0 1.9e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69749.1 - 8.4e-13 48.5 0.1 2.1e-10 40.8 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF2785 PF10978.8 GBG69749.1 - 0.023 14.5 1.7 0.13 12.0 1.7 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) zf-CCHC_6 PF15288.6 GBG69749.1 - 0.16 11.8 0.4 0.42 10.5 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG69749.1 - 0.26 11.4 4.1 0.58 10.3 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG69752.1 - 8.7e-11 41.7 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG69752.1 - 1.4e-08 34.5 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69752.1 - 1.3e-07 32.1 0.0 2.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69752.1 - 2.1e-07 31.4 0.0 3.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG69752.1 - 0.0004 20.2 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease NifU PF01106.17 GBG69753.1 - 2.8e-28 97.9 0.5 3.4e-23 81.6 0.2 3.1 2 1 0 2 2 2 2 NifU-like domain DUF4091 PF13320.6 GBG69753.1 - 0.076 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) ATP-sulfurylase PF01747.17 GBG69755.1 - 5.6e-66 222.0 0.0 7.3e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 GBG69755.1 - 2.1e-44 151.0 0.0 3.5e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain SR-25 PF10500.9 GBG69755.1 - 2.7 7.6 12.6 5 6.7 12.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NIF PF03031.18 GBG69756.1 - 3.7e-43 147.0 0.0 4.8e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GBG69756.1 - 0.12 12.8 0.0 3.5 8.0 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase RVT_1 PF00078.27 GBG69757.1 - 7.6e-10 38.7 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cgr1 PF03879.14 GBG69758.1 - 4.9e-08 33.3 24.9 4.9e-08 33.3 24.9 1.9 2 0 0 2 2 2 1 Cgr1 family ABC_tran PF00005.27 GBG69758.1 - 0.021 15.4 1.2 0.027 15.0 1.2 1.2 1 0 0 1 1 1 0 ABC transporter Vfa1 PF08432.10 GBG69760.1 - 0.0083 16.5 5.2 0.0083 16.5 4.1 1.6 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF3760 PF12586.8 GBG69760.1 - 0.041 14.1 0.5 0.17 12.1 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3760) Yae1_N PF09811.9 GBG69760.1 - 0.05 13.3 4.0 0.05 13.3 4.0 3.8 2 1 1 3 3 3 0 Essential protein Yae1, N terminal DUF1561 PF07598.11 GBG69760.1 - 0.081 11.1 0.0 0.095 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) DUF4661 PF15576.6 GBG69763.1 - 1 9.3 3.5 2 8.3 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) zf-CCHC PF00098.23 GBG69764.1 - 3.5e-06 26.8 5.3 4.5e-06 26.5 3.7 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG69764.1 - 0.0052 16.6 3.8 0.026 14.4 3.9 2.0 2 0 0 2 2 2 1 Zinc knuckle Atg14 PF10186.9 GBG69764.1 - 0.44 9.6 9.2 0.6 9.1 9.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MMM1 PF10296.9 GBG69764.1 - 0.52 9.3 3.4 0.84 8.6 3.4 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Chloroa_b-bind PF00504.21 GBG69765.1 - 0.00084 19.9 0.2 0.0017 18.9 0.0 1.6 2 0 0 2 2 2 1 Chlorophyll A-B binding protein Tic110 PF16940.5 GBG69765.1 - 4.3 5.7 7.3 5.1 5.5 7.3 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter RT_RNaseH_2 PF17919.1 GBG69766.1 - 8e-21 74.0 0.3 9.1e-14 51.3 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69766.1 - 8.4e-20 71.0 2.7 2.5e-12 47.0 1.5 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69766.1 - 1.9e-13 50.5 0.0 3.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69766.1 - 9.5e-06 25.8 0.1 3.9e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DUF1564 PF07600.11 GBG69766.1 - 0.041 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DUF5095 PF17016.5 GBG69766.1 - 0.15 11.7 0.3 0.28 10.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Sec34 PF04136.15 GBG69767.1 - 1.5 8.7 9.0 8.9 6.2 1.2 2.7 2 0 0 2 2 2 0 Sec34-like family RVT_1 PF00078.27 GBG69768.1 - 2.8e-25 89.1 0.1 1.1e-23 83.9 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_1 PF00036.32 GBG69769.1 - 6.2e-32 106.7 11.7 2.6e-08 32.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GBG69769.1 - 9.2e-30 102.9 3.3 7.9e-16 58.3 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG69769.1 - 7.3e-24 81.6 6.4 1.6e-08 33.8 0.1 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GBG69769.1 - 1.3e-22 78.2 10.8 1.5e-07 30.6 0.1 4.5 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GBG69769.1 - 4.7e-21 74.4 8.3 1.7e-08 34.1 0.6 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 GBG69769.1 - 1.9e-11 44.1 0.1 0.00012 22.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GBG69769.1 - 1.5e-07 31.3 2.5 0.00018 21.4 0.4 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GBG69769.1 - 6.1e-07 29.8 0.1 0.006 16.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GBG69769.1 - 3.1e-05 24.1 0.5 0.00019 21.5 0.2 2.3 2 1 1 3 3 3 1 Dockerin type I domain EF-hand_11 PF08976.11 GBG69769.1 - 0.00019 22.3 0.0 0.31 11.9 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain TerB PF05099.13 GBG69769.1 - 0.00028 20.8 1.0 0.1 12.5 0.1 2.5 1 1 1 3 3 3 2 Tellurite resistance protein TerB Caleosin PF05042.13 GBG69769.1 - 0.0017 18.3 0.0 2.5 8.0 0.0 2.8 2 2 1 3 3 3 2 Caleosin related protein SurA_N_3 PF13624.6 GBG69769.1 - 0.0037 17.1 1.6 0.083 12.7 0.1 2.1 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 GBG69769.1 - 0.0038 17.5 0.5 2 8.8 0.1 2.4 1 1 1 2 2 2 1 EF-hand domain SurA_N_2 PF13623.6 GBG69769.1 - 0.0048 16.8 3.7 0.36 10.7 0.1 2.5 1 1 1 2 2 2 1 SurA N-terminal domain UBA_6 PF18039.1 GBG69769.1 - 0.0061 16.5 0.8 3.8 7.5 0.0 2.5 2 0 0 2 2 2 2 UBA-like domain Rota_NSP3 PF01665.16 GBG69769.1 - 0.012 14.8 1.0 0.027 13.6 0.0 1.8 1 1 1 2 2 2 0 Rotavirus non-structural protein NSP3 DUF2666 PF10869.8 GBG69769.1 - 0.014 15.6 4.0 2 8.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DUF5580 PF17743.1 GBG69769.1 - 0.057 11.9 0.0 0.11 11.0 0.0 1.4 1 1 1 2 2 2 0 Family of unknown function (DUF5580) HrpJ PF07201.11 GBG69769.1 - 0.08 13.2 1.2 2 8.7 0.1 2.0 1 1 1 2 2 2 0 HrpJ-like domain Mu-like_Pro PF10123.9 GBG69769.1 - 0.09 12.3 1.6 0.1 12.2 1.6 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Sen15 PF09631.10 GBG69769.1 - 0.093 13.0 0.1 6.6 7.1 0.0 2.1 1 1 1 2 2 2 0 Sen15 protein HU-DNA_bdg PF14848.6 GBG69769.1 - 0.12 12.4 2.5 2.7 8.0 0.1 2.8 1 1 2 3 3 3 0 DNA-binding domain MotA_activ PF09114.10 GBG69769.1 - 0.12 12.5 0.3 10 6.3 0.1 2.2 1 1 1 2 2 2 0 Transcription factor MotA, activation domain DUF1636 PF07845.11 GBG69769.1 - 0.18 12.2 0.0 28 5.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1636) DUF1456 PF07308.13 GBG69769.1 - 0.22 11.9 3.2 3.2 8.1 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) Fe_hyd_lg_C PF02906.14 GBG69769.1 - 0.75 9.4 4.0 3.3 7.3 4.0 2.0 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain V_ATPase_I PF01496.19 GBG69770.1 - 3.6e-266 885.2 5.1 9.8e-229 761.4 0.0 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DUF3935 PF13071.6 GBG69770.1 - 3.9 8.1 8.9 5.2 7.7 0.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3935) zf-CCHC PF00098.23 GBG69771.1 - 5.9e-06 26.1 3.9 1.4e-05 25.0 3.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG69771.1 - 0.0091 15.8 3.6 0.017 15.0 3.6 1.5 1 0 0 1 1 1 1 Zinc knuckle XRN_N PF03159.18 GBG69771.1 - 0.49 9.8 8.6 0.82 9.1 8.6 1.3 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus WDCP PF15390.6 GBG69771.1 - 4.3 5.6 9.7 5.4 5.3 9.7 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Hydrolase_4 PF12146.8 GBG69773.1 - 5.5e-60 202.6 0.0 6.3e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GBG69773.1 - 1.2e-11 44.5 0.0 6.3e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GBG69773.1 - 2.7e-10 41.2 0.0 3.3e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG69773.1 - 1.7e-07 31.2 0.0 3.2e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GBG69773.1 - 2e-05 24.5 0.2 0.00081 19.3 0.0 2.7 2 1 1 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GBG69773.1 - 7.5e-05 22.5 0.0 0.00019 21.1 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 GBG69773.1 - 0.00016 21.5 0.3 0.11 12.3 0.1 2.6 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase AXE1 PF05448.12 GBG69773.1 - 0.00021 20.1 0.5 0.086 11.5 0.3 3.0 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 GBG69773.1 - 0.0011 18.5 0.0 0.58 9.7 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 GBG69773.1 - 0.029 14.0 0.1 0.06 13.0 0.1 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 GBG69773.1 - 0.05 13.2 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF740 PF05340.12 GBG69774.1 - 0.0066 15.3 1.4 0.0072 15.1 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF740) DUF4360 PF14273.6 GBG69777.1 - 1.6e-32 112.8 0.0 2.2e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Fra10Ac1 PF09725.9 GBG69778.1 - 1.4e-45 154.4 4.3 2.3e-45 153.7 4.3 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 RVT_1 PF00078.27 GBG69779.1 - 7.2e-06 25.7 0.1 1.1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG69779.1 - 0.027 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69779.1 - 0.061 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease PHO4 PF01384.20 GBG69780.1 - 1.6e-91 306.9 4.6 2.3e-91 306.4 4.6 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF1129 PF06570.11 GBG69780.1 - 0.0021 17.6 3.0 0.0044 16.5 3.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) GIY-YIG PF01541.24 GBG69780.1 - 0.032 14.5 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 GIY-YIG catalytic domain PHO4 PF01384.20 GBG69781.1 - 3.4e-51 174.3 0.0 9.6e-51 172.8 0.0 1.5 1 1 0 1 1 1 1 Phosphate transporter family Chromo PF00385.24 GBG69781.1 - 2.7e-12 46.4 0.0 5.9e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Spc7 PF08317.11 GBG69781.1 - 0.063 12.2 5.4 0.042 12.7 3.4 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Pre-PUA PF17832.1 GBG69781.1 - 0.15 12.8 0.0 15 6.3 0.0 3.1 3 0 0 3 3 3 0 Pre-PUA-like domain Toprim_N PF08275.11 GBG69782.1 - 0.00031 20.8 5.8 15 5.6 0.0 5.9 2 2 4 6 6 6 1 DNA primase catalytic core, N-terminal domain RTA1 PF04479.13 GBG69782.1 - 0.00036 20.2 8.7 10 5.7 0.1 6.0 2 2 5 7 7 7 2 RTA1 like protein PapC_C PF13953.6 GBG69782.1 - 0.0019 18.0 20.0 2.3 8.1 1.0 6.1 1 1 6 7 7 7 4 PapC C-terminal domain DUF2917 PF11142.8 GBG69782.1 - 0.12 11.8 0.3 0.12 11.8 0.3 4.6 2 2 4 6 6 6 0 Protein of unknown function (DUF2917) DdrB PF12747.7 GBG69782.1 - 0.15 11.9 12.8 2.3 8.0 1.8 4.6 1 1 5 6 6 6 0 DdrB-like protein ATP_transf PF09830.9 GBG69782.1 - 0.28 11.4 7.1 31 4.8 0.1 5.1 1 1 3 4 4 4 0 ATP adenylyltransferase Methyltransf_1N PF02870.15 GBG69782.1 - 0.31 11.9 3.5 15 6.5 0.1 3.6 2 2 1 3 3 3 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain SH3_19 PF18597.1 GBG69782.1 - 0.8 9.6 21.7 14 5.6 0.1 6.0 6 1 1 7 7 7 0 Myosin X N-terminal SH3 domain RVT_1 PF00078.27 GBG69783.1 - 2.8e-28 99.0 0.0 4.6e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69783.1 - 2.2e-16 59.7 0.0 6.4e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69783.1 - 0.00015 22.0 0.0 0.00039 20.7 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG69783.1 - 0.0034 18.0 0.0 0.016 15.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease DUF659 PF04937.15 GBG69785.1 - 8.2e-17 61.5 0.1 1.4e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) YL1 PF05764.13 GBG69785.1 - 0.073 13.2 4.8 0.88 9.6 0.1 2.7 2 0 0 2 2 2 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GBG69785.1 - 7.7 6.2 15.7 0.47 10.1 4.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RWP-RK PF02042.15 GBG69787.1 - 2.2e-19 69.2 0.2 5.6e-19 67.8 0.2 1.7 2 0 0 2 2 2 1 RWP-RK domain RWP-RK PF02042.15 GBG69788.1 - 2.2e-19 69.2 0.2 5.6e-19 67.8 0.2 1.7 2 0 0 2 2 2 1 RWP-RK domain MbeD_MobD PF04899.12 GBG69789.1 - 0.028 14.5 1.1 5 7.3 0.4 2.7 2 1 0 2 2 2 0 MbeD/MobD like ParB PF08775.10 GBG69789.1 - 0.079 13.4 0.0 0.079 13.4 0.0 3.3 2 1 1 4 4 4 0 ParB family BHD_2 PF10404.9 GBG69789.1 - 0.81 10.7 15.1 2.8 9.0 2.4 2.8 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 DUF4972 PF16342.5 GBG69789.1 - 4.9 6.9 10.9 1.2 8.8 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4972) RR_TM4-6 PF06459.12 GBG69789.1 - 8.4 6.1 13.2 15 5.3 13.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Retrotrans_gag PF03732.17 GBG69790.1 - 0.00034 20.8 0.9 0.002 18.4 0.0 2.8 4 0 0 4 4 4 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG69791.1 - 5.1e-35 119.5 0.1 7.6e-35 119.0 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69791.1 - 6e-22 77.9 0.0 1.1e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PI3Ka PF00613.20 GBG69791.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) SDA1 PF05285.12 GBG69792.1 - 0.0051 16.3 20.6 0.0057 16.1 20.6 1.0 1 0 0 1 1 1 1 SDA1 Presenilin PF01080.17 GBG69792.1 - 0.057 12.2 9.7 0.066 12.0 9.7 1.0 1 0 0 1 1 1 0 Presenilin DUF4366 PF14283.6 GBG69792.1 - 2.6 8.1 9.0 21 5.1 9.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Zip PF02535.22 GBG69792.1 - 5.1 6.2 6.4 6.4 5.9 6.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.6 GBG69792.1 - 6 5.5 10.8 7.3 5.2 10.8 1.0 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 GBG69792.1 - 7.5 4.7 24.3 9.1 4.4 24.3 1.0 1 0 0 1 1 1 0 CDC45-like protein gpUL132 PF11359.8 GBG69793.1 - 0.00081 19.0 0.4 0.16 11.5 0.0 2.4 2 0 0 2 2 2 2 Glycoprotein UL132 DUF919 PF06034.11 GBG69793.1 - 0.019 14.8 0.9 0.019 14.8 0.9 3.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Es2 PF09751.9 GBG69793.1 - 0.25 11.0 12.9 0.43 10.3 12.9 1.4 1 0 0 1 1 1 0 Nuclear protein Es2 T2SSF PF00482.23 GBG69793.1 - 1 9.3 4.3 0.56 10.2 0.4 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF919 PF06034.11 GBG69794.1 - 0.0061 16.4 0.9 0.0061 16.4 0.9 3.6 3 1 1 4 4 4 1 Nucleopolyhedrovirus protein of unknown function (DUF919) Es2 PF09751.9 GBG69794.1 - 2.3 7.8 18.6 2.3 7.9 17.4 1.5 1 1 1 2 2 2 0 Nuclear protein Es2 RT_RNaseH_2 PF17919.1 GBG69795.1 - 3.8e-30 103.9 0.0 1.6e-29 101.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69795.1 - 1.9e-28 98.8 0.0 3.6e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glyco_hydr_116N PF12215.8 GBG69795.1 - 3.5e-17 62.9 0.1 5.8e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Asp_protease PF09668.10 GBG69795.1 - 0.048 13.5 0.0 9.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Phage_GPO PF05929.11 GBG69795.1 - 0.095 12.3 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG69796.1 - 2.9e-49 167.6 0.1 2e-27 96.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69796.1 - 5.8e-31 106.5 0.0 1.4e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69796.1 - 3.4e-26 91.6 0.1 9.4e-26 90.2 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG69796.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Virul_fac_BrkB PF03631.15 GBG69796.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Virulence factor BrkB DUF5095 PF17016.5 GBG69796.1 - 0.21 11.3 0.1 0.44 10.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) LMBR1 PF04791.16 GBG69797.1 - 0.91 8.4 5.5 1.5 7.6 5.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Glyco_hydr_116N PF12215.8 GBG69798.1 - 2.4e-20 73.2 0.0 2.6e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF608 PF04685.13 GBG69799.1 - 2.3e-96 323.1 4.0 3.3e-57 194.3 2.3 2.2 1 1 1 2 2 2 2 Glycosyl-hydrolase family 116, catalytic region rve PF00665.26 GBG69799.1 - 4.7e-07 30.0 0.1 2.2e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG69799.1 - 2.1e-06 27.7 0.5 6.1e-06 26.3 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG69799.1 - 0.023 15.0 3.3 0.1 12.9 0.0 3.2 3 0 0 3 3 3 0 Retrotransposon gag protein Rho_Binding PF08912.11 GBG69799.1 - 0.42 11.5 3.8 1.4 9.8 3.8 1.9 1 0 0 1 1 1 0 Rho Binding RVT_1 PF00078.27 GBG69800.1 - 1.6e-29 103.1 0.1 2.6e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69800.1 - 1e-08 35.1 0.0 7.9e-08 32.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG69800.1 - 9.1e-08 32.6 0.0 3.4e-07 30.7 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69800.1 - 9.4e-08 32.6 0.0 3e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69800.1 - 2.1e-06 27.6 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG69800.1 - 0.00034 20.4 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG69803.1 - 1e-30 107.0 0.1 1.9e-30 106.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69803.1 - 1.7e-23 82.9 0.1 5.2e-23 81.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69803.1 - 3.6e-23 81.5 0.0 8.2e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69803.1 - 8.8e-19 67.4 0.2 1.8e-18 66.3 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69803.1 - 3.7e-09 36.8 0.0 8.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG69803.1 - 0.00017 21.4 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG69803.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PPR_2 PF13041.6 GBG69804.1 - 3.3e-86 283.3 12.3 2.1e-11 43.8 0.3 14.6 6 5 10 16 16 16 13 PPR repeat family PPR PF01535.20 GBG69804.1 - 1.2e-75 244.6 31.1 2e-07 30.8 0.1 18.0 18 0 0 18 18 18 15 PPR repeat PPR_1 PF12854.7 GBG69804.1 - 2.2e-62 206.4 0.0 1.2e-08 34.5 0.0 13.1 13 0 0 13 13 13 10 PPR repeat PPR_3 PF13812.6 GBG69804.1 - 1.9e-56 188.0 0.0 1.1e-12 47.8 0.0 9.8 8 2 2 10 10 10 8 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG69804.1 - 9e-20 70.9 1.9 1.3e-06 27.9 0.0 5.9 3 1 3 6 6 6 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GBG69804.1 - 0.00041 20.9 13.6 22 6.2 0.0 9.2 7 2 4 11 11 9 0 Tetratricopeptide repeat MRP-S27 PF10037.9 GBG69804.1 - 0.0059 15.5 0.0 17 4.1 0.0 4.1 4 1 0 4 4 4 0 Mitochondrial 28S ribosomal protein S27 MNE1 PF13762.6 GBG69804.1 - 0.01 15.9 0.0 4.2 7.3 0.0 3.3 1 1 0 2 2 2 0 Mitochondrial splicing apparatus component TPR_7 PF13176.6 GBG69804.1 - 0.01 15.8 6.8 13 6.0 0.0 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat Vps39_1 PF10366.9 GBG69804.1 - 0.071 13.4 0.0 2.6 8.4 0.0 3.3 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 TPR_16 PF13432.6 GBG69804.1 - 0.098 13.3 3.0 36 5.1 0.0 5.0 5 2 0 5 5 4 0 Tetratricopeptide repeat Clathrin PF00637.20 GBG69804.1 - 0.11 12.3 0.0 18 5.2 0.0 3.7 5 0 0 5 5 5 0 Region in Clathrin and VPS TPR_6 PF13174.6 GBG69804.1 - 0.34 11.6 1.6 1.5e+02 3.3 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat GTP_cyclohydroI PF01227.22 GBG69805.1 - 4.8e-50 169.5 6.3 5.8e-18 64.9 0.1 4.3 4 0 0 4 4 4 4 GTP cyclohydrolase I DUF5610 PF18433.1 GBG69805.1 - 0.00014 22.4 7.1 1.5 9.3 0.1 4.0 4 0 0 4 4 4 3 Domain of unknown function (DUF5610) DNA_pol_phi PF04931.13 GBG69805.1 - 2.9 5.9 26.3 4.3 5.3 26.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Osteopontin PF00865.18 GBG69805.1 - 3.9 6.9 21.7 8 5.9 21.7 1.4 1 0 0 1 1 1 0 Osteopontin Nop14 PF04147.12 GBG69805.1 - 7.8 4.6 16.6 13 3.8 16.6 1.2 1 0 0 1 1 1 0 Nop14-like family Integrase_H2C2 PF17921.1 GBG69807.1 - 1.7e-19 69.6 0.4 3.5e-19 68.7 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG69807.1 - 5.6e-19 68.5 0.2 1.7e-18 66.9 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69807.1 - 2.7e-11 43.7 0.5 5.7e-11 42.6 0.5 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG69807.1 - 3.1e-08 34.1 0.0 7.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69807.1 - 7.1e-07 29.1 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG69807.1 - 5.8e-06 26.5 0.2 5.3e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG69807.1 - 2e-05 25.1 0.0 7e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG69807.1 - 0.0024 17.9 0.1 0.006 16.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG69807.1 - 0.016 15.5 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG69807.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Integrin_b_cyt PF08725.11 GBG69807.1 - 0.13 11.9 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain WRC PF08879.10 GBG69808.1 - 2.1e-13 49.7 18.1 2e-09 37.0 7.6 2.7 2 0 0 2 2 2 2 WRC TFIIA PF03153.13 GBG69808.1 - 0.031 14.3 10.3 0.045 13.8 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 GBG69808.1 - 1.5 9.2 8.4 3.7 7.9 8.4 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 GBG69808.1 - 1.6 7.4 8.4 2.4 6.8 8.4 1.1 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 GBG69808.1 - 1.6 8.0 4.3 2.4 7.5 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) zf-TRM13_CCCH PF11722.8 GBG69808.1 - 7.3 6.5 9.6 4.8 7.0 2.4 2.6 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein Spt20 PF12090.8 GBG69808.1 - 7.6 6.1 19.8 12 5.5 19.8 1.1 1 0 0 1 1 1 0 Spt20 family Spc7 PF08317.11 GBG69809.1 - 0.55 9.1 29.5 0.1 11.5 9.3 3.5 2 1 1 3 3 3 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.13 GBG69809.1 - 0.64 9.5 11.0 1.4 8.5 0.9 3.4 2 1 1 3 3 3 0 fzo-like conserved region DUF3138 PF11336.8 GBG69809.1 - 3.4 6.2 6.9 3.2 6.3 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) DUF1943 PF09172.11 GBG69809.1 - 4.6 6.4 9.2 0.24 10.6 3.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) RVT_1 PF00078.27 GBG69810.1 - 6.9e-29 100.9 0.0 9.9e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG69810.1 - 1.1e-07 31.7 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69810.1 - 0.00011 22.7 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69810.1 - 0.001 19.6 0.0 0.0017 18.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease NIF PF03031.18 GBG69810.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase UPF0242 PF06785.11 GBG69811.1 - 2.7 8.1 10.0 2.8 8.0 2.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus gag-asp_proteas PF13975.6 GBG69814.1 - 1.7e-10 41.3 0.0 4.6e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69814.1 - 4.8e-07 30.3 0.0 1.2e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG69814.1 - 0.016 15.5 0.0 0.076 13.3 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG69814.1 - 0.057 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG69815.1 - 5.6e-24 84.1 0.0 8.8e-24 83.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69815.1 - 6e-23 81.1 0.0 1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG69815.1 - 0.22 9.7 6.1 0.28 9.4 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG69815.1 - 0.6 8.3 6.4 0.81 7.9 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG69815.1 - 1.1 8.6 8.5 1.5 8.1 8.5 1.1 1 0 0 1 1 1 0 SDA1 CHRD PF07452.12 GBG69816.1 - 4.8e-10 40.4 0.0 7.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 CHRD domain SDA1 PF05285.12 GBG69817.1 - 0.00023 20.7 22.7 0.00027 20.5 22.7 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG69817.1 - 0.00038 18.9 14.4 0.0004 18.8 14.4 1.0 1 0 0 1 1 1 1 CDC45-like protein SpoIIIAH PF12685.7 GBG69817.1 - 0.058 13.2 11.7 0.097 12.5 11.7 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 GBG69817.1 - 0.1 10.8 30.8 0.13 10.5 30.8 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG69817.1 - 0.24 10.7 28.0 0.3 10.4 28.0 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG69817.1 - 0.27 10.0 12.0 0.33 9.7 12.0 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG69817.1 - 0.31 9.8 7.0 0.34 9.6 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.10 GBG69817.1 - 0.46 10.8 14.8 0.65 10.3 14.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 GBG69817.1 - 0.5 10.5 2.1 0.63 10.2 2.1 1.3 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 GBG69817.1 - 1.3 8.1 7.6 1.5 7.9 7.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Astro_capsid_p PF12226.8 GBG69817.1 - 1.9 7.6 21.2 2.7 7.0 21.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Neur_chan_memb PF02932.16 GBG69817.1 - 2.2 8.3 3.7 2.7 8.0 3.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIF_alpha PF05793.12 GBG69817.1 - 3.6 6.1 32.7 4 5.9 32.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.12 GBG69817.1 - 4.5 7.0 20.7 7.2 6.3 20.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 GBG69817.1 - 4.7 5.0 9.9 6.1 4.6 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 GBG69817.1 - 5.2 5.9 9.6 6.7 5.6 9.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 GBG69817.1 - 5.9 4.8 6.6 7.7 4.5 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) LAP1C PF05609.12 GBG69817.1 - 7.5 5.5 15.6 9.3 5.2 15.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RVT_1 PF00078.27 GBG69819.1 - 8.6e-29 100.6 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69819.1 - 9.2e-16 57.7 0.0 1.6e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69819.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NDK PF00334.19 GBG69820.1 - 1.1e-53 180.8 0.0 1.3e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF659 PF04937.15 GBG69821.1 - 2e-06 27.7 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Chorein_N PF12624.7 GBG69822.1 - 7.4e-38 129.2 0.0 8.4e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 GBG69823.1 - 3.3e-14 53.3 0.0 5.1e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal RRM_1 PF00076.22 GBG69824.1 - 0.00044 20.0 0.0 0.0009 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG69824.1 - 0.00094 19.1 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RVT_1 PF00078.27 GBG69825.1 - 1.4e-23 83.6 0.1 2.8e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG69825.1 - 2.9e-11 43.3 0.0 8.8e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG69825.1 - 0.0038 17.5 1.3 0.015 15.5 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein She9_MDM33 PF05546.11 GBG69825.1 - 1.1 9.0 0.0 1.1 9.0 0.0 3.1 4 0 0 4 4 4 0 She9 / Mdm33 family RT_RNaseH_2 PF17919.1 GBG69826.1 - 4.3e-13 49.1 0.0 1.5e-09 37.8 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69826.1 - 9.5e-09 35.5 0.0 0.0032 17.7 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG69826.1 - 5.8e-05 23.6 0.0 0.00017 22.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG69826.1 - 0.011 16.0 0.0 0.037 14.3 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG69826.1 - 0.048 13.9 1.8 0.43 10.9 0.7 2.8 2 1 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG69826.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF4187 PF13821.6 GBG69827.1 - 0.0049 16.6 0.6 0.025 14.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG69827.1 - 0.0064 16.7 0.2 0.023 15.0 0.0 2.0 2 1 1 3 3 3 1 Retrotransposon gag protein TRPM_tetra PF16519.5 GBG69827.1 - 0.1 12.7 0.7 16 5.7 0.1 3.0 3 0 0 3 3 3 0 Tetramerisation domain of TRPM DUF659 PF04937.15 GBG69828.1 - 9.9e-34 116.4 0.0 1.9e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG69828.1 - 6.7e-25 87.0 0.0 1.6e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69828.1 - 7.7e-25 87.7 0.1 1.4e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69828.1 - 2e-22 79.4 0.0 8.8e-22 77.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69828.1 - 3.7e-15 55.8 0.8 1e-14 54.4 0.8 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69828.1 - 9.3e-05 22.6 0.0 0.0017 18.5 0.0 2.8 2 0 0 2 2 2 1 Integrase core domain adh_short_C2 PF13561.6 GBG69828.1 - 0.52 9.8 4.7 1.1 8.8 4.3 1.7 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RVT_1 PF00078.27 GBG69829.1 - 2.6e-31 108.9 0.0 5e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69829.1 - 8.3e-15 55.0 0.0 2.3e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG69829.1 - 3.4e-13 49.5 0.0 7.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG69829.1 - 5e-07 29.6 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG69829.1 - 7.5e-05 23.3 0.0 0.00019 22.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG69829.1 - 0.00017 21.3 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69829.1 - 0.00022 21.7 0.0 0.00074 20.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG69829.1 - 0.00076 19.7 0.0 0.0034 17.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HALZ PF02183.18 GBG69829.1 - 0.05 13.8 1.0 0.13 12.5 1.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Fascin PF06268.13 GBG69829.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Fascin domain bZIP_1 PF00170.21 GBG69829.1 - 3.1 8.0 5.4 0.79 9.9 1.5 2.0 2 0 0 2 2 1 0 bZIP transcription factor bZIP_2 PF07716.15 GBG69829.1 - 3.3 7.8 10.5 0.63 10.2 3.1 2.9 2 0 0 2 2 2 0 Basic region leucine zipper RVT_1 PF00078.27 GBG69830.1 - 5.3e-09 35.9 0.2 7.4e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69832.1 - 1.8e-34 117.8 0.1 4.9e-34 116.3 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69832.1 - 2.2e-30 105.1 0.4 8.6e-30 103.1 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69832.1 - 1.3e-15 57.6 0.0 5.2e-15 55.7 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG69832.1 - 4e-10 39.7 1.1 1e-09 38.3 1.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG69832.1 - 3.4e-08 33.3 0.1 6.7e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG69832.1 - 0.0051 16.7 1.5 0.014 15.3 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG69834.1 - 1.2e-23 83.0 0.0 2.1e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69834.1 - 5.1e-19 68.1 0.2 9.7e-19 67.2 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG69834.1 - 1.1e-13 51.3 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69835.1 - 7e-30 104.2 0.1 9.6e-30 103.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69836.1 - 8e-23 80.4 0.0 1.7e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69836.1 - 4.8e-20 71.8 0.1 1.9e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69836.1 - 5.1e-13 49.1 0.5 1.5e-08 34.5 0.1 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG69836.1 - 0.0095 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG69836.1 - 0.21 11.9 0.1 0.21 11.9 0.1 3.1 4 0 0 4 4 4 0 Retrotransposon gag protein DUF5401 PF17380.2 GBG69836.1 - 0.28 9.2 1.7 0.5 8.4 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF659 PF04937.15 GBG69837.1 - 2.7e-30 105.3 0.0 2.7e-30 105.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG69837.1 - 1.1e-05 25.1 0.8 2.3e-05 24.1 0.8 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG69837.1 - 0.058 13.3 3.3 0.23 11.4 3.3 2.1 1 0 0 1 1 1 0 AT hook motif Presenilin PF01080.17 GBG69837.1 - 9.7 4.8 9.9 17 4.0 9.9 1.3 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 GBG69838.1 - 0.054 13.3 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GBG69839.1 - 2e-08 33.9 3.8 3.6e-08 33.1 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF4834 PF16118.5 GBG69839.1 - 0.0079 17.1 0.3 0.029 15.3 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4834) zf-CCHC_2 PF13696.6 GBG69839.1 - 0.0084 15.9 1.0 0.014 15.2 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG69839.1 - 0.048 13.5 2.3 0.14 12.1 2.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG69839.1 - 0.057 13.4 0.3 0.14 12.1 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF2813 PF11398.8 GBG69839.1 - 0.13 11.5 2.3 0.19 11.0 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) DUF3496 PF12001.8 GBG69840.1 - 0.0067 16.8 0.6 0.01 16.2 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3496) DUF4619 PF15398.6 GBG69840.1 - 0.014 14.9 2.6 0.019 14.5 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) PASTA PF03793.19 GBG69840.1 - 0.027 14.3 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 PASTA domain GCD14 PF08704.10 GBG69840.1 - 0.39 10.3 3.4 0.64 9.6 2.3 1.7 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Atrophin-1 PF03154.15 GBG69840.1 - 0.89 7.8 4.7 1.1 7.5 4.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family SDA1 PF05285.12 GBG69841.1 - 1.9e-06 27.6 41.7 2.2e-06 27.3 41.7 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG69841.1 - 2.1e-05 23.0 40.0 2.7e-05 22.6 40.0 1.2 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 GBG69841.1 - 0.0059 16.0 42.8 0.0069 15.8 42.8 1.1 1 0 0 1 1 1 1 BUD22 CCSAP PF15748.5 GBG69841.1 - 0.088 13.0 27.2 0.13 12.4 27.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF262 PF03235.14 GBG69841.1 - 0.27 11.4 7.8 0.3 11.2 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Plasmodium_Vir PF05795.11 GBG69841.1 - 0.48 9.8 15.4 0.61 9.5 15.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4045 PF13254.6 GBG69841.1 - 0.53 9.9 23.8 0.68 9.5 23.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 GBG69841.1 - 1.6 7.4 26.6 1.9 7.2 26.6 1.2 1 0 0 1 1 1 0 Presenilin MDM1 PF15501.6 GBG69841.1 - 2.9 6.9 34.1 4.3 6.4 34.1 1.3 1 0 0 1 1 1 0 Nuclear protein MDM1 LAP1C PF05609.12 GBG69841.1 - 8.9 5.3 27.6 11 5.0 27.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG69842.1 - 0.058 11.6 14.0 0.072 11.3 14.0 1.1 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.6 GBG69842.1 - 0.62 8.8 6.8 0.79 8.4 6.8 1.1 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 GBG69842.1 - 0.68 8.2 15.9 0.9 7.8 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG69842.1 - 1.8 7.8 16.5 2.8 7.2 16.5 1.3 1 0 0 1 1 1 0 NOA36 protein Paramyxo_ncap PF00973.19 GBG69842.1 - 3.5 6.4 7.1 5.5 5.8 7.1 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RRN3 PF05327.11 GBG69842.1 - 9.9 4.6 8.5 13 4.2 8.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF659 PF04937.15 GBG69843.1 - 3.1e-33 114.8 0.0 5.5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG69843.1 - 2.6e-06 27.1 0.1 1.2e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF2076 PF09849.9 GBG69844.1 - 6.9 6.6 7.6 19 5.2 7.6 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RT_RNaseH PF17917.1 GBG69845.1 - 8.2e-22 77.5 0.0 2.3e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69845.1 - 5.4e-20 71.3 0.0 1.9e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69845.1 - 1.8e-15 56.8 0.2 4e-15 55.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Myb_DNA-bind_4 PF13837.6 GBG69845.1 - 8.7e-06 26.0 2.8 2.5e-05 24.5 2.8 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain rve PF00665.26 GBG69845.1 - 2.6e-05 24.4 0.0 5.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Myb_DNA-bind_5 PF13873.6 GBG69845.1 - 0.00048 20.1 1.1 0.0025 17.8 0.8 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain zf-H2C2 PF09337.10 GBG69845.1 - 0.0019 18.3 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Myb_DNA-bind_6 PF13921.6 GBG69845.1 - 0.021 15.1 1.8 0.039 14.2 0.9 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF4187 PF13821.6 GBG69845.1 - 0.14 12.0 0.5 0.4 10.5 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-CCHC PF00098.23 GBG69845.1 - 0.24 11.6 0.7 0.59 10.3 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG69846.1 - 1.4e-06 28.5 2.8 3.8e-06 27.2 2.8 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG69846.1 - 6.7e-05 22.9 1.6 0.00043 20.3 0.8 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG69846.1 - 0.0033 17.7 0.9 0.0066 16.7 0.9 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG69846.1 - 0.022 15.1 0.6 0.064 13.6 0.6 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG69846.1 - 0.035 14.3 1.2 0.15 12.3 0.5 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain LOB PF03195.14 GBG69847.1 - 1e-08 35.6 0.0 2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Lateral organ boundaries (LOB) domain zf-CCHC PF00098.23 GBG69848.1 - 9.7e-06 25.4 2.2 2.3e-05 24.3 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG69848.1 - 0.052 13.5 0.8 0.16 11.9 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG69848.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG69848.1 - 0.16 11.8 2.3 0.37 10.7 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Atg14 PF10186.9 GBG69848.1 - 1.2 8.1 7.2 1.8 7.6 7.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS6_N PF14661.6 GBG69848.1 - 1.3 8.6 0.0 1.3 8.6 0.0 2.9 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus DUF3089 PF11288.8 GBG69849.1 - 0.17 11.4 0.0 0.45 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) NOA36 PF06524.12 GBG69850.1 - 0.12 11.7 11.9 0.17 11.2 11.9 1.2 1 0 0 1 1 1 0 NOA36 protein HNF-1_N PF04814.13 GBG69850.1 - 0.27 11.8 8.5 0.079 13.6 4.9 1.8 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Hamartin PF04388.12 GBG69850.1 - 1.2 7.7 12.0 1.6 7.3 12.0 1.2 1 0 0 1 1 1 0 Hamartin protein CDC27 PF09507.10 GBG69850.1 - 5.1 6.4 23.7 0.23 10.8 18.6 1.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Nucleo_P87 PF07267.11 GBG69850.1 - 6.4 5.5 6.9 7.9 5.2 6.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF992 PF06186.11 GBG69853.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF992) MAP70 PF07058.11 GBG69854.1 - 5.1e-124 415.0 43.0 1.2e-100 337.9 27.4 2.6 3 0 0 3 3 3 2 Microtubule-associated protein 70 FAM76 PF16046.5 GBG69854.1 - 0.0064 15.9 0.3 0.0064 15.9 0.3 4.1 3 1 1 5 5 5 3 FAM76 protein Lebercilin PF15619.6 GBG69854.1 - 0.01 15.5 57.5 0.96 9.1 0.5 4.9 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF848 PF05852.11 GBG69854.1 - 1.8 8.7 35.5 0.11 12.6 4.1 4.6 3 1 0 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) RVT_1 PF00078.27 GBG69856.1 - 1.3e-28 100.1 0.0 2e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pol_alpha_B_N PF08418.10 GBG69858.1 - 0.13 12.2 6.9 0.54 10.2 0.6 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Fib_alpha PF08702.10 GBG69858.1 - 0.15 12.3 10.1 0.3 11.3 0.4 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family NAPRTase_C PF17956.1 GBG69858.1 - 0.2 12.1 4.4 3.4 8.1 0.1 3.2 2 1 0 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF4192 PF13830.6 GBG69858.1 - 0.58 10.2 16.5 2.1 8.3 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) DUF4404 PF14357.6 GBG69858.1 - 1.7 9.3 18.3 0.32 11.7 3.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) DUF4407 PF14362.6 GBG69858.1 - 3.5 6.9 18.0 0.64 9.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ALMT PF11744.8 GBG69858.1 - 8.5 5.1 6.9 3.4 6.4 3.7 1.7 1 1 1 2 2 2 0 Aluminium activated malate transporter RT_RNaseH_2 PF17919.1 GBG69859.1 - 1.4e-21 76.4 0.0 4.4e-21 74.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69859.1 - 6.2e-12 45.7 0.0 2.1e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69859.1 - 0.096 12.2 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69860.1 - 2.5e-24 85.2 0.0 6.9e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69860.1 - 4.5e-24 84.8 0.0 1.3e-23 83.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69860.1 - 1.6e-22 80.1 0.0 2.8e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG69860.1 - 4.4e-19 68.3 0.4 1.1e-18 67.1 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69860.1 - 7.4e-09 35.8 0.0 4.1e-08 33.4 0.0 2.4 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG69860.1 - 1.3e-05 25.7 0.0 0.00014 22.4 0.0 2.5 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG69860.1 - 4.1e-05 23.4 0.0 8.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG69860.1 - 0.00012 22.3 0.1 0.00059 20.0 0.1 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG69860.1 - 0.00014 22.3 0.0 0.0007 20.1 0.0 2.2 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG69860.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease Chromo PF00385.24 GBG69860.1 - 0.045 13.7 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG69860.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve PF00665.26 GBG69861.1 - 5.7e-08 33.0 0.0 1.5e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG69861.1 - 0.068 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG69862.1 - 1.6e-18 67.1 0.0 2.2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG69862.1 - 9.3e-07 28.7 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG69862.1 - 3.7e-06 27.4 0.0 7.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69862.1 - 7.1e-06 26.6 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG69862.1 - 6.5e-05 22.7 0.1 0.00037 20.3 0.0 2.0 1 1 1 2 2 2 1 Aspartyl protease DUF4404 PF14357.6 GBG69863.1 - 0.026 15.1 2.4 0.026 15.1 2.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Baculo_PEP_C PF04513.12 GBG69863.1 - 0.1 12.6 2.2 2.9 7.9 0.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AIP3 PF03915.13 GBG69863.1 - 0.39 9.8 13.8 0.25 10.4 11.2 1.9 1 1 1 2 2 2 0 Actin interacting protein 3 RNR_Alpha PF17975.1 GBG69863.1 - 3.9 8.0 5.5 3 8.4 0.2 2.4 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain PIEZO PF15917.5 GBG69863.1 - 4.2 6.8 8.5 3.9 6.9 6.4 1.9 2 1 0 2 2 2 0 Piezo DUF572 PF04502.13 GBG69863.1 - 6.4 6.3 13.1 8.1 6.0 13.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) rve PF00665.26 GBG69864.1 - 2.1e-14 53.7 0.0 2.6e-11 43.7 0.0 3.8 3 0 0 3 3 3 1 Integrase core domain DUF659 PF04937.15 GBG69864.1 - 7.9e-14 51.8 0.0 2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG69864.1 - 0.00068 19.2 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 GBG69864.1 - 0.0091 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Bd3614_N PF14442.6 GBG69865.1 - 0.16 12.3 0.1 0.36 11.2 0.1 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal PRTP PF01366.18 GBG69865.1 - 0.81 7.7 4.1 1.6 6.6 4.1 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RT_RNaseH_2 PF17919.1 GBG69867.1 - 1.5e-20 73.1 0.0 3.2e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69867.1 - 1.8e-20 73.2 0.0 4.1e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69867.1 - 1.1e-12 48.2 0.0 3.7e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG69867.1 - 8.7e-06 25.8 0.0 2.6e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG69867.1 - 0.0047 16.7 0.0 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-CCHC_4 PF14392.6 GBG69869.1 - 0.093 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle SCAB-PH PF17684.1 GBG69869.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein RVT_1 PF00078.27 GBG69870.1 - 4.5e-64 216.0 0.5 5.5e-33 114.3 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69870.1 - 7e-30 103.0 0.0 1.6e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69870.1 - 1.4e-22 80.0 0.0 3.6e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG69870.1 - 5.9e-09 35.8 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG69870.1 - 0.00011 22.3 0.1 0.00047 20.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG69870.1 - 0.00032 21.3 0.0 0.0013 19.3 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG69870.1 - 0.0035 17.9 0.0 0.021 15.3 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease FlgN PF05130.12 GBG69870.1 - 0.019 15.5 2.8 0.06 13.9 2.8 1.9 1 0 0 1 1 1 0 FlgN protein FlxA PF14282.6 GBG69870.1 - 0.38 10.8 2.2 1.9 8.5 2.2 2.2 1 0 0 1 1 1 0 FlxA-like protein Phage_GPO PF05929.11 GBG69870.1 - 1.6 8.3 8.7 4 7.0 0.0 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG69871.1 - 4.6e-21 74.7 0.0 1.4e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69871.1 - 1.1e-10 41.8 0.0 2.9e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69871.1 - 2e-10 40.6 0.0 3.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG69872.1 - 0.0027 17.6 0.5 0.0059 16.6 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG69873.1 - 2.3e-25 88.5 0.0 4.2e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69873.1 - 9.3e-22 77.3 0.0 1.9e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69873.1 - 2.6e-15 56.7 0.0 6.9e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG69873.1 - 3e-11 43.3 0.0 8e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG69873.1 - 0.0047 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain FAM60A PF15396.6 GBG69875.1 - 0.43 10.6 7.2 0.49 10.4 7.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Cellulose_synt PF03552.14 GBG69875.1 - 0.59 8.5 5.8 0.68 8.4 5.8 1.0 1 0 0 1 1 1 0 Cellulose synthase IncFII_repA PF02387.15 GBG69875.1 - 0.62 9.2 7.8 0.89 8.7 7.8 1.1 1 0 0 1 1 1 0 IncFII RepA protein family DUF4375 PF14300.6 GBG69875.1 - 2.5 8.4 7.8 4.3 7.6 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Hydin_ADK PF17213.3 GBG69875.1 - 3.8 7.7 7.1 4.7 7.4 7.1 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RVT_1 PF00078.27 GBG69877.1 - 4.9e-29 101.4 0.1 6.4e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69878.1 - 8.7e-32 109.1 0.1 2.4e-31 107.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69878.1 - 5.1e-28 97.4 0.2 1.1e-27 96.4 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Na_H_Exchanger PF00999.21 GBG69878.1 - 9.8e-19 67.4 0.2 1.5e-18 66.8 0.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2259 PF10016.9 GBG69878.1 - 0.016 15.2 0.6 0.038 13.9 0.6 1.6 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) zf-CCHC_6 PF15288.6 GBG69878.1 - 0.12 12.2 0.7 0.27 11.1 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle MgtE PF01769.16 GBG69878.1 - 0.14 12.6 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Divalent cation transporter CotJB PF12652.7 GBG69878.1 - 0.14 12.4 0.4 14 6.0 0.0 3.1 3 0 0 3 3 3 0 CotJB protein zf-CCHC PF00098.23 GBG69878.1 - 0.22 11.7 4.1 0.39 10.9 4.1 1.4 1 0 0 1 1 1 0 Zinc knuckle FAM199X PF15814.5 GBG69878.1 - 2.1 7.3 10.5 5.6 5.9 10.5 1.6 1 0 0 1 1 1 0 Protein family FAM199X RGCC PF15151.6 GBG69878.1 - 2.3 8.4 0.0 2.3 8.4 0.0 3.0 2 1 1 3 3 3 0 Response gene to complement 32 protein family RVT_1 PF00078.27 GBG69879.1 - 3.4e-20 72.5 0.0 5.4e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG69880.1 - 6.4e-05 22.8 2.4 0.00022 21.1 2.4 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG69880.1 - 8.7e-05 22.4 4.3 0.00017 21.5 4.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG69880.1 - 0.001 18.8 3.8 0.0017 18.1 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle SeleniumBinding PF11524.8 GBG69881.1 - 0.062 13.7 13.5 19 5.8 0.4 5.8 1 1 5 6 6 6 0 Selenium binding protein FlgH PF02107.16 GBG69881.1 - 0.89 9.1 3.5 17 5.0 0.2 3.1 2 1 0 3 3 3 0 Flagellar L-ring protein CstA PF02554.14 GBG69881.1 - 0.91 8.4 2.8 26 3.5 0.0 3.1 2 2 2 4 4 4 0 Carbon starvation protein CstA Elong-fact-P_C PF09285.11 GBG69881.1 - 3.1 7.6 9.5 51 3.7 0.1 4.5 2 2 1 3 3 3 0 Elongation factor P, C-terminal RVT_1 PF00078.27 GBG69882.1 - 5e-26 91.6 0.0 7.5e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG69882.1 - 0.083 12.9 0.1 8.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L34 RT_RNaseH PF17917.1 GBG69883.1 - 1e-77 257.2 0.0 1.7e-28 98.9 0.0 4.0 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69883.1 - 2.5e-76 252.1 0.0 4e-29 100.6 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69883.1 - 3.6e-45 154.2 0.8 3.4e-28 98.7 0.1 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69883.1 - 4.6e-24 84.9 0.0 8e-13 48.6 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain Na_H_Exchanger PF00999.21 GBG69883.1 - 7.5e-19 67.8 7.3 1e-18 67.4 7.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Integrase_H2C2 PF17921.1 GBG69883.1 - 2.1e-16 59.7 0.1 5.9e-16 58.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG69883.1 - 0.00032 20.4 0.0 0.0068 16.2 0.0 3.0 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG69883.1 - 0.0065 16.3 0.0 0.023 14.6 0.0 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-H2C2 PF09337.10 GBG69883.1 - 0.016 15.4 0.0 0.088 13.0 0.0 2.4 2 0 0 2 2 2 0 H2C2 zinc finger Chromo PF00385.24 GBG69883.1 - 0.12 12.2 1.5 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain U-box PF04564.15 GBG69884.1 - 2.6e-20 72.3 0.0 5.9e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 U-box domain Arm PF00514.23 GBG69884.1 - 0.00019 21.4 0.6 0.00098 19.1 0.0 2.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat zf-Nse PF11789.8 GBG69884.1 - 0.00088 19.0 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit HEAT_2 PF13646.6 GBG69884.1 - 0.044 14.2 0.3 0.16 12.4 0.3 1.9 1 0 0 1 1 1 0 HEAT repeats FTA4 PF13093.6 GBG69884.1 - 0.13 12.1 1.8 0.23 11.3 1.8 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4407 PF14362.6 GBG69884.1 - 1.8 7.9 3.6 3.6 6.9 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG69886.1 - 7.1e-17 61.7 0.1 1.1e-16 61.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sorb PF02208.16 GBG69886.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Sorbin homologous domain zf-CCHC PF00098.23 GBG69888.1 - 0.29 11.3 3.6 0.29 11.3 0.7 2.3 2 0 0 2 2 2 0 Zinc knuckle Radial_spoke_3 PF06098.11 GBG69888.1 - 0.64 9.3 16.8 22 4.2 16.2 2.2 2 0 0 2 2 2 0 Radial spoke protein 3 RVT_1 PF00078.27 GBG69889.1 - 1.6e-53 181.5 0.5 8.1e-27 94.2 0.1 2.6 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69889.1 - 1.6e-20 73.4 0.0 4.6e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69889.1 - 5.7e-14 52.0 1.1 1.2e-13 50.9 0.0 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG69889.1 - 2.5e-11 43.5 0.0 6.4e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG69889.1 - 1.4e-07 31.1 0.2 1.1e-06 28.3 0.1 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-H2C2 PF09337.10 GBG69889.1 - 0.0012 19.0 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF4399 PF14347.6 GBG69889.1 - 0.0059 16.9 0.0 0.81 10.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4399) VirDNA-topo-I_N PF09266.10 GBG69889.1 - 0.14 12.3 0.9 7.4 6.8 0.1 2.7 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal RT_RNaseH_2 PF17919.1 GBG69890.1 - 1.9e-21 76.0 0.0 4.6e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69890.1 - 2.2e-21 76.1 0.0 6.8e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG69890.1 - 6.6e-13 48.9 0.0 1.5e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG69890.1 - 1.9e-12 47.1 0.4 4e-12 46.1 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG69890.1 - 7.9e-05 23.2 0.1 0.00073 20.0 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69890.1 - 0.014 16.0 0.1 0.047 14.3 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease zf-H2C2 PF09337.10 GBG69890.1 - 0.033 14.4 0.9 0.076 13.2 0.9 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG69890.1 - 0.095 12.5 0.9 0.25 11.2 0.9 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG69892.1 - 9.6e-17 61.3 0.0 2.5e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG69892.1 - 0.0021 17.8 0.2 0.0067 16.2 0.1 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Macoilin PF09726.9 GBG69893.1 - 1.8 7.0 14.7 2.7 6.5 14.7 1.3 1 0 0 1 1 1 0 Macoilin family DUF4553 PF15090.6 GBG69893.1 - 6.9 5.5 33.8 8.9 5.2 33.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) DUF1682 PF07946.14 GBG69894.1 - 7.2e-53 179.9 18.0 6.4e-45 153.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1682) Integrase_H2C2 PF17921.1 GBG69895.1 - 1.5e-15 57.0 0.1 3.4e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69895.1 - 5.1e-06 26.7 0.0 9.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG69895.1 - 0.0017 18.5 0.0 0.004 17.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG69895.1 - 0.011 16.3 0.0 0.03 15.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG69895.1 - 0.017 15.7 0.0 0.044 14.4 0.0 1.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease PLATZ PF04640.14 GBG69896.1 - 2.9e-13 50.2 0.3 2.9e-13 50.2 0.3 3.4 3 0 0 3 3 3 1 PLATZ transcription factor RNA_pol_3_Rpc31 PF11705.8 GBG69896.1 - 0.0041 17.4 20.2 0.0041 17.4 20.2 4.6 4 1 0 4 4 4 2 DNA-directed RNA polymerase III subunit Rpc31 PLATZ PF04640.14 GBG69897.1 - 2.4e-13 50.5 0.3 2.4e-13 50.5 0.3 3.8 5 0 0 5 5 5 1 PLATZ transcription factor RNA_pol_3_Rpc31 PF11705.8 GBG69897.1 - 0.0023 18.2 19.7 0.0023 18.2 19.7 3.5 3 1 0 3 3 3 2 DNA-directed RNA polymerase III subunit Rpc31 Radial_spoke PF04712.12 GBG69897.1 - 0.009 15.0 6.0 0.009 15.0 6.0 3.8 3 1 0 3 3 3 1 Radial spokehead-like protein FAM176 PF14851.6 GBG69897.1 - 0.02 14.6 1.2 0.02 14.6 1.2 4.6 4 1 0 4 4 4 0 FAM176 family O-antigen_lig PF13425.6 GBG69897.1 - 0.65 8.7 0.0 0.65 8.7 0.0 3.3 3 1 0 3 3 3 0 O-antigen ligase like membrane protein RNA_pol_Rpc4 PF05132.14 GBG69897.1 - 2.1 8.7 27.9 0.064 13.7 6.1 3.8 3 1 0 3 3 3 0 RNA polymerase III RPC4 Caldesmon PF02029.15 GBG69897.1 - 4 6.1 46.8 0.17 10.6 1.6 3.1 3 0 0 3 3 3 0 Caldesmon SDA1 PF05285.12 GBG69897.1 - 4.7 6.5 62.2 0.75 9.2 5.4 3.1 3 0 0 3 3 3 0 SDA1 Tankyrase_bdg_C PF15327.6 GBG69897.1 - 7.4 7.0 17.1 3 8.3 0.3 2.9 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain KOG2701 PF09762.9 GBG69898.1 - 0.0074 16.5 0.2 0.0074 16.5 0.2 2.5 2 2 1 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) YscK PF06578.12 GBG69898.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) TGS PF02824.21 GBG69898.1 - 0.13 12.3 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 TGS domain SieB PF14163.6 GBG69898.1 - 0.14 11.7 0.1 0.31 10.5 0.1 1.6 1 0 0 1 1 1 0 Super-infection exclusion protein B DivIC PF04977.15 GBG69898.1 - 0.17 11.7 0.1 0.17 11.7 0.1 4.8 4 1 1 5 5 5 0 Septum formation initiator DUF4337 PF14235.6 GBG69900.1 - 0.29 11.2 5.9 0.36 10.9 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Fusion_gly PF00523.18 GBG69900.1 - 0.71 8.1 3.6 0.85 7.8 3.6 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF3267 PF11667.8 GBG69900.1 - 1.8 8.9 9.8 2.8 8.2 9.2 1.6 1 1 1 2 2 2 0 Putative zincin peptidase E1-E2_ATPase PF00122.20 GBG69900.1 - 1.9 8.0 6.2 2.4 7.6 6.2 1.1 1 0 0 1 1 1 0 E1-E2 ATPase DUF1192 PF06698.11 GBG69901.1 - 0.085 12.9 0.3 0.23 11.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) GRP PF07172.11 GBG69902.1 - 0.084 13.6 35.3 0.1 13.3 35.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family IQ PF00612.27 GBG69903.1 - 0.011 15.5 19.1 0.65 10.0 1.4 4.0 3 0 0 3 3 3 0 IQ calmodulin-binding motif Pept_tRNA_hydro PF01195.19 GBG69905.1 - 4.5e-53 179.7 0.0 6.2e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PPP4R2 PF09184.11 GBG69905.1 - 0.11 12.1 2.5 0.16 11.6 2.5 1.3 1 0 0 1 1 1 0 PPP4R2 SBP_bac_3 PF00497.20 GBG69906.1 - 0.019 14.4 0.3 0.022 14.2 0.3 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DNA_pol_phi PF04931.13 GBG69906.1 - 0.13 10.4 3.8 0.14 10.2 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3689 PF12463.8 GBG69908.1 - 1.3e-81 274.4 0.0 2e-64 217.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3689) mCpol PF18182.1 GBG69908.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 minimal CRISPR polymerase domain DUF3689 PF12463.8 GBG69909.1 - 1.2e-81 274.4 0.0 2e-64 217.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3689) mCpol PF18182.1 GBG69909.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 minimal CRISPR polymerase domain DEAD PF00270.29 GBG69910.1 - 1.9e-40 138.5 0.0 4e-40 137.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG69910.1 - 4.2e-22 78.6 0.0 1.5e-21 76.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG69910.1 - 0.00019 21.5 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG69910.1 - 0.17 11.2 0.0 0.17 11.2 0.0 2.1 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit LSM PF01423.22 GBG69912.1 - 9.5e-08 31.6 0.2 5.1e-07 29.3 0.1 1.8 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 GBG69912.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Hfq protein HECT PF00632.25 GBG69914.1 - 1.6e-81 274.2 0.0 2.3e-81 273.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 GBG69914.1 - 2.8e-08 33.5 9.4 0.0061 16.6 0.3 6.5 5 1 1 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GBG69914.1 - 0.00048 20.5 0.1 1.7 9.0 0.0 4.0 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 GBG69914.1 - 0.00079 19.5 1.0 0.51 10.7 0.1 3.7 3 0 0 3 3 3 1 HEAT repeat Keratin_assoc PF09775.9 GBG69914.1 - 0.0053 16.4 0.2 0.01 15.5 0.2 1.4 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 HEAT_EZ PF13513.6 GBG69914.1 - 0.0086 16.6 4.4 0.027 15.0 0.2 3.7 3 0 0 3 3 3 1 HEAT-like repeat UNC45-central PF11701.8 GBG69914.1 - 0.038 14.0 1.4 0.23 11.4 0.0 2.8 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Cwf_Cwc_15 PF04889.12 GBG69914.1 - 1.9 8.1 20.8 6.1 6.5 20.8 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG69914.1 - 7.5 4.6 16.3 13 3.8 16.3 1.3 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG69915.1 - 2.1e-21 75.8 0.0 5.3e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69915.1 - 2.8e-20 72.6 0.0 1.2e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69915.1 - 1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG69917.1 - 1.4e-14 54.3 0.0 3.3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69917.1 - 7.7e-11 41.9 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG69917.1 - 0.061 13.6 0.0 3.3 8.0 0.0 3.3 3 0 0 3 3 3 0 Retrotransposon gag protein Phage_GPO PF05929.11 GBG69917.1 - 0.3 10.7 3.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG69918.1 - 1.2e-62 208.2 0.0 9.9e-32 109.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69918.1 - 4.7e-59 197.2 0.5 1.8e-28 98.9 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69918.1 - 3.5e-35 119.9 7.2 7.5e-18 64.4 1.2 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG69918.1 - 5.6e-23 81.6 0.5 2.3e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69918.1 - 1.2e-16 60.9 0.1 5.6e-13 49.1 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG69918.1 - 2.1e-05 24.7 1.3 0.15 12.3 0.2 2.7 2 0 0 2 2 2 2 H2C2 zinc finger GRP PF07172.11 GBG69918.1 - 1.3 9.8 29.4 0.64 10.7 21.3 2.9 2 0 0 2 2 2 0 Glycine rich protein family RT_RNaseH PF17917.1 GBG69919.1 - 1.1e-23 83.5 0.0 2.6e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69919.1 - 1.2e-21 76.6 0.0 2.3e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69919.1 - 3.4e-18 65.5 0.1 8.6e-18 64.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG69919.1 - 2.2e-15 56.8 0.1 1.3e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG69919.1 - 2.4e-08 34.2 0.1 2.1e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG69919.1 - 0.0086 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG69920.1 - 4.9e-08 32.7 0.1 6.7e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG69920.1 - 0.16 11.3 20.5 0.21 10.9 20.5 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG69920.1 - 2.2 6.5 16.3 2.7 6.2 16.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG69920.1 - 2.5 7.4 22.1 3.1 7.1 22.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG69920.1 - 2.6 6.2 23.4 3.2 5.8 23.4 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG69920.1 - 7.3 5.2 10.0 13 4.5 10.0 1.3 1 0 0 1 1 1 0 Presenilin Lactamase_B_6 PF16661.5 GBG69921.1 - 6.2e-58 195.4 0.1 1.3e-57 194.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 GBG69921.1 - 1.4e-20 73.6 0.0 2.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 GBG69921.1 - 3e-11 43.1 0.1 6.8e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CPSF100_C PF13299.6 GBG69921.1 - 4.5e-09 36.7 0.1 0.00042 20.5 0.0 2.6 1 1 1 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B PF00753.27 GBG69921.1 - 1.7e-06 28.2 0.1 4.1e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GBG69921.1 - 4.2e-06 26.4 0.1 1.2e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 GBG69922.1 - 6.2e-58 195.4 0.1 1.3e-57 194.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 GBG69922.1 - 1.4e-20 73.6 0.0 2.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 GBG69922.1 - 2.9e-11 43.1 0.1 6.9e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CPSF100_C PF13299.6 GBG69922.1 - 4.1e-09 36.8 0.1 0.00042 20.5 0.0 2.7 1 1 1 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B PF00753.27 GBG69922.1 - 1.7e-06 28.2 0.1 4.1e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GBG69922.1 - 4.2e-06 26.4 0.1 1.2e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RT_RNaseH_2 PF17919.1 GBG69923.1 - 9.2e-27 93.0 0.0 1.7e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69923.1 - 7.5e-24 84.0 0.0 1.6e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG69923.1 - 9.4e-06 25.5 3.2 1.9e-05 24.5 3.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG69923.1 - 0.018 14.9 4.1 0.037 13.9 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle ATG_C PF09333.11 GBG69923.1 - 0.059 13.7 0.1 0.38 11.1 0.1 2.3 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain SAPS PF04499.15 GBG69923.1 - 3.1 6.5 5.5 5 5.8 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NARP1 PF12569.8 GBG69923.1 - 9.2 5.0 10.0 15 4.3 10.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RT_RNaseH_2 PF17919.1 GBG69924.1 - 6.2e-27 93.6 0.0 1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69924.1 - 6e-24 84.3 0.0 9.6e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SAPS PF04499.15 GBG69924.1 - 2.1 7.0 5.5 2.9 6.6 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RPN2_C PF18004.1 GBG69924.1 - 4.3 7.2 12.2 12 5.8 12.2 1.9 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NARP1 PF12569.8 GBG69924.1 - 7.7 5.3 12.0 9.3 5.0 10.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Proteasome PF00227.26 GBG69926.1 - 6.6e-62 208.4 0.0 8.2e-62 208.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Serinc PF03348.15 GBG69927.1 - 0.94 8.3 3.8 3 6.7 3.8 1.6 1 1 0 1 1 1 0 Serine incorporator (Serinc) RT_RNaseH_2 PF17919.1 GBG69928.1 - 2.7e-28 97.9 0.0 6.1e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69928.1 - 1.5e-24 86.3 0.0 3.2e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69928.1 - 9.7e-23 80.8 0.0 1.5e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG69928.1 - 0.48 8.6 6.2 0.65 8.1 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG69928.1 - 2.1 6.6 8.1 2.8 6.1 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG69929.1 - 6e-62 205.9 0.1 8e-33 112.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69929.1 - 3.2e-59 197.7 0.0 1.3e-30 105.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69929.1 - 4.9e-29 101.4 0.1 6.4e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG69929.1 - 0.013 15.4 0.1 3.4 7.6 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) RT_RNaseH_2 PF17919.1 GBG69930.1 - 1.7e-33 114.6 0.0 3.2e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69930.1 - 2.4e-31 108.1 0.0 5.3e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69930.1 - 5.5e-08 32.6 0.1 8.2e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACT_4 PF13291.6 GBG69932.1 - 1.9e-07 31.6 0.0 0.02 15.5 0.0 3.7 4 0 0 4 4 4 2 ACT domain ACT PF01842.25 GBG69932.1 - 9.9e-05 22.0 0.1 0.1 12.4 0.0 3.5 3 0 0 3 3 3 1 ACT domain Mito_carr PF00153.27 GBG69935.1 - 2.5e-53 178.0 3.8 7.1e-20 70.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 GBG69935.1 - 0.0067 16.3 0.0 7.2 6.6 0.0 2.9 3 0 0 3 3 3 2 UcrQ family Wbp11 PF09429.10 GBG69936.1 - 5.5e-24 84.4 13.5 1.4e-23 83.1 13.5 1.7 1 0 0 1 1 1 1 WW domain binding protein 11 YL1 PF05764.13 GBG69936.1 - 0.0071 16.5 12.1 0.0071 16.5 12.1 2.4 2 0 0 2 2 2 1 YL1 nuclear protein BUD22 PF09073.10 GBG69936.1 - 0.056 12.8 28.5 0.1 11.9 20.3 2.3 2 0 0 2 2 2 0 BUD22 SpoIIIAH PF12685.7 GBG69936.1 - 7.9 6.2 14.4 18 5.1 14.4 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Myb_DNA-bind_4 PF13837.6 GBG69937.1 - 6.8e-06 26.4 0.9 1.1e-05 25.7 0.9 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Fe-S_biosyn PF01521.20 GBG69938.1 - 6.2e-21 74.7 0.0 7.1e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF659 PF04937.15 GBG69939.1 - 2.3e-19 69.7 0.0 4.2e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG69939.1 - 0.21 11.4 0.7 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG69940.1 - 1.4e-18 67.2 0.1 2.4e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69940.1 - 1.6e-17 63.4 0.0 5.5e-16 58.4 0.0 2.4 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69940.1 - 7.7e-15 55.1 0.0 2.5e-14 53.4 0.0 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase VIR_N PF15912.5 GBG69940.1 - 3.9 7.0 11.6 5.9 6.4 11.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal N6_N4_Mtase PF01555.18 GBG69941.1 - 3.6e-11 43.2 0.6 7.4e-06 25.8 0.0 3.2 3 0 0 3 3 3 2 DNA methylase Methyltransf_25 PF13649.6 GBG69941.1 - 0.025 15.3 0.1 17 6.2 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain Presenilin PF01080.17 GBG69941.1 - 3.3 6.4 14.8 0.35 9.6 6.6 2.5 2 0 0 2 2 2 0 Presenilin CDC45 PF02724.14 GBG69942.1 - 1.2e-11 43.7 83.5 0.00081 17.8 17.7 4.3 4 0 0 4 4 4 4 CDC45-like protein Nop14 PF04147.12 GBG69942.1 - 4.3e-06 25.3 135.0 0.00011 20.6 24.2 4.3 4 0 0 4 4 4 3 Nop14-like family Caldesmon PF02029.15 GBG69942.1 - 0.00032 19.6 14.8 0.00032 19.6 14.8 5.4 5 1 0 6 6 5 2 Caldesmon Complex1_49kDa PF00346.19 GBG69942.1 - 0.00034 19.8 0.0 2.2 7.3 0.0 3.2 3 0 0 3 3 3 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit FAM165 PF14981.6 GBG69942.1 - 0.0061 16.3 2.0 21 5.0 0.0 3.7 3 0 0 3 3 3 0 FAM165 family POP1 PF06978.11 GBG69942.1 - 0.011 15.8 0.3 33 4.4 0.0 3.7 3 0 0 3 3 3 0 Ribonucleases P/MRP protein subunit POP1 N6_N4_Mtase PF01555.18 GBG69942.1 - 0.013 15.3 2.7 0.13 12.0 0.0 3.5 2 1 0 2 2 2 0 DNA methylase MoaC PF01967.21 GBG69942.1 - 0.098 12.8 0.1 26 4.9 0.0 3.2 3 0 0 3 3 3 0 MoaC family DUF3043 PF11241.8 GBG69942.1 - 0.36 10.8 9.8 0.39 10.7 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) SDA1 PF05285.12 GBG69942.1 - 1 8.7 162.3 0.12 11.7 35.0 5.0 5 0 0 5 5 5 0 SDA1 PH_4 PF15404.6 GBG69942.1 - 2.9 7.7 27.6 3.6 7.3 3.8 4.4 4 0 0 4 4 4 0 Pleckstrin homology domain Rhamnogal_lyase PF06045.11 GBG69943.1 - 4.9e-28 98.0 3.5 5e-19 68.6 0.2 3.9 2 1 1 3 3 3 2 Rhamnogalacturonate lyase family Sigma70_ner PF04546.13 GBG69944.1 - 0.00055 19.9 4.7 0.00055 19.9 4.7 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region PPP4R2 PF09184.11 GBG69944.1 - 0.0032 17.1 6.9 0.0032 17.1 6.9 1.1 1 0 0 1 1 1 1 PPP4R2 Astro_capsid_p PF12226.8 GBG69944.1 - 0.012 14.8 11.1 0.011 14.9 11.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TRAP_alpha PF03896.16 GBG69944.1 - 0.015 14.5 6.4 0.018 14.2 6.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.11 GBG69944.1 - 0.045 12.3 8.8 0.043 12.4 8.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 GBG69944.1 - 0.13 12.3 13.3 0.12 12.4 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GCIP PF13324.6 GBG69944.1 - 0.13 11.8 8.0 0.16 11.5 8.0 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting TFB6 PF17110.5 GBG69944.1 - 0.14 11.9 5.3 0.16 11.7 5.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2796 PF10986.8 GBG69944.1 - 0.15 12.0 3.7 0.2 11.6 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) NOA36 PF06524.12 GBG69944.1 - 0.18 11.1 24.6 0.23 10.7 24.6 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 GBG69944.1 - 0.21 9.7 4.0 0.19 9.8 4.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 GBG69944.1 - 0.79 9.1 15.3 0.93 8.9 15.3 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GBG69944.1 - 1.3 8.0 31.6 1.7 7.7 31.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GBG69944.1 - 2.8 5.9 29.3 3.4 5.7 29.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG69944.1 - 3.1 5.9 19.6 3.5 5.7 19.6 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 GBG69944.1 - 3.2 7.1 16.0 4.7 6.5 16.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GBG69944.1 - 6.8 4.8 16.7 8 4.6 16.7 1.0 1 0 0 1 1 1 0 CDC45-like protein E1-E2_ATPase PF00122.20 GBG69946.1 - 6.6e-42 143.1 1.7 6.6e-42 143.1 1.7 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 GBG69946.1 - 1.1e-14 54.3 0.0 2.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GBG69946.1 - 1.8e-12 48.0 0.1 7.9e-12 45.9 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GBG69946.1 - 1.6e-09 37.3 0.0 3.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF3792 PF12670.7 GBG69946.1 - 0.036 14.2 2.5 0.051 13.7 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) CaATP_NAI PF12515.8 GBG69946.1 - 0.16 11.6 0.7 0.41 10.3 0.7 1.6 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain TMEM234 PF10639.9 GBG69948.1 - 7.4e-16 58.2 0.0 1.6e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 Putative transmembrane family 234 Connexin PF00029.19 GBG69948.1 - 0.011 15.5 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 0 Connexin Rhabdo_ncap_2 PF03216.13 GBG69948.1 - 0.019 14.4 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleoprotein Presenilin PF01080.17 GBG69948.1 - 0.022 13.5 4.5 0.026 13.3 4.5 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 GBG69948.1 - 0.056 12.4 0.9 0.062 12.3 0.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 GBG69948.1 - 0.067 12.0 5.9 0.076 11.8 5.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 GBG69948.1 - 0.069 13.3 0.3 0.081 13.1 0.3 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 GBG69948.1 - 0.074 12.9 7.1 0.085 12.7 7.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Smg8_Smg9 PF10220.9 GBG69948.1 - 0.14 10.4 2.8 0.16 10.2 2.8 1.0 1 0 0 1 1 1 0 Smg8_Smg9 MAP17 PF15807.5 GBG69948.1 - 0.19 11.9 4.8 0.31 11.3 4.8 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Zip PF02535.22 GBG69948.1 - 0.36 10.0 3.6 0.46 9.6 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF5427 PF10310.9 GBG69948.1 - 0.45 9.4 10.2 0.53 9.2 10.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) V_ATPase_I PF01496.19 GBG69948.1 - 0.65 7.8 4.7 0.74 7.7 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL32 PF06070.11 GBG69948.1 - 3 5.5 5.1 3.8 5.1 5.1 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Hid1 PF12722.7 GBG69948.1 - 4.8 5.2 5.9 5.6 5.0 5.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RPN2_C PF18004.1 GBG69948.1 - 8.8 6.2 16.4 12 5.8 16.4 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Exo_endo_phos PF03372.23 GBG69949.1 - 0.00028 20.5 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MAP17 PF15807.5 GBG69949.1 - 0.055 13.7 0.5 0.2 11.9 0.5 1.9 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Paf1 PF03985.13 GBG69949.1 - 3 6.7 10.1 4.3 6.2 10.1 1.1 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.16 GBG69949.1 - 8.5 5.5 9.7 14 4.7 9.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RT_RNaseH_2 PF17919.1 GBG69950.1 - 3.8e-34 116.7 0.1 7e-34 115.9 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69950.1 - 2.1e-31 108.3 0.1 4.7e-31 107.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69950.1 - 1.9e-16 59.9 1.1 4.3e-16 58.8 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG69950.1 - 0.00029 21.0 0.1 0.0046 17.1 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG69950.1 - 0.039 14.2 0.7 0.12 12.7 0.1 2.2 2 0 0 2 2 2 0 H2C2 zinc finger RVT_1 PF00078.27 GBG69951.1 - 5.1e-25 88.3 0.1 1.1e-24 87.2 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GalKase_gal_bdg PF10509.9 GBG69951.1 - 3.6e-08 32.8 0.3 7.8e-08 31.8 0.3 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 GBG69951.1 - 0.0001 22.5 0.2 0.00025 21.2 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Asp_protease_2 PF13650.6 GBG69951.1 - 0.16 12.6 0.0 0.48 11.1 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG69952.1 - 1.6e-29 103.0 0.1 3.1e-29 102.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69952.1 - 7.6e-23 80.5 0.0 2.2e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69952.1 - 8e-21 74.3 0.0 3.2e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69952.1 - 2.9e-15 56.1 0.8 1.9e-14 53.5 0.2 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG69952.1 - 0.0022 18.2 0.1 0.0061 16.7 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF4187 PF13821.6 GBG69952.1 - 0.0091 15.8 0.5 0.026 14.3 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RVP_2 PF08284.11 GBG69952.1 - 0.016 15.0 0.1 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG69953.1 - 5.3e-35 119.5 0.0 9.4e-35 118.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG69953.1 - 1.5e-21 76.7 0.0 3e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG69953.1 - 5.6e-17 62.0 0.0 1.1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RCC_reductase PF06405.11 GBG69953.1 - 0.035 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) DUF3863 PF12979.7 GBG69953.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) zf-CCHC PF00098.23 GBG69955.1 - 9.4e-07 28.6 3.0 1.5e-06 28.0 3.0 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF1892 PF08987.10 GBG69955.1 - 0.011 15.9 3.1 0.025 14.8 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) LMBR1 PF04791.16 GBG69955.1 - 0.11 11.4 10.0 0.13 11.1 10.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-CCHC_6 PF15288.6 GBG69955.1 - 0.13 12.1 1.4 0.34 10.8 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle SSP160 PF06933.11 GBG69955.1 - 0.29 9.3 1.7 0.36 9.0 1.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CDC45 PF02724.14 GBG69955.1 - 0.29 9.4 11.7 0.32 9.2 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG69955.1 - 0.34 10.3 10.0 0.43 9.9 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Prominin PF05478.11 GBG69955.1 - 0.73 7.7 6.5 0.86 7.5 6.5 1.2 1 0 0 1 1 1 0 Prominin zf-CCHC_2 PF13696.6 GBG69955.1 - 0.86 9.5 4.0 1.4 8.8 4.0 1.3 1 0 0 1 1 1 0 Zinc knuckle Sec62 PF03839.16 GBG69955.1 - 3.4 7.1 13.0 4.7 6.7 13.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 XRN_M PF17846.1 GBG69955.1 - 3.8 6.4 9.7 4.4 6.1 9.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain HSP70 PF00012.20 GBG69955.1 - 6.9 4.7 16.8 8.6 4.4 16.8 1.2 1 0 0 1 1 1 0 Hsp70 protein Presenilin PF01080.17 GBG69955.1 - 7.2 5.3 12.9 8.8 5.0 12.9 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 GBG69955.1 - 7.4 6.6 9.6 9.4 6.2 9.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pannexin_like PF12534.8 GBG69955.1 - 9.4 5.2 10.3 12 4.8 10.3 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Myb_DNA-bind_4 PF13837.6 GBG69956.1 - 8.9e-10 38.8 1.0 2.8e-09 37.2 1.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG69956.1 - 0.0064 16.8 0.2 0.021 15.2 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG69957.1 - 1.3e-28 99.7 0.0 2.3e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG69957.1 - 3.1e-13 49.8 0.0 6.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG69957.1 - 0.00083 19.1 0.2 0.17 11.5 0.0 2.3 2 1 0 2 2 2 2 Transposase DDE domain Ion_trans PF00520.31 GBG69958.1 - 5.2e-18 65.2 9.8 7.4e-18 64.7 9.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 GBG69958.1 - 1.6e-10 40.8 1.9 3.7e-10 39.6 1.9 1.7 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 GBG69958.1 - 0.004 17.2 0.1 0.91 9.6 0.0 2.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain DNA_pol_phi PF04931.13 GBG69958.1 - 1.5 6.9 5.9 2.2 6.3 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 GBG69958.1 - 1.8 8.7 13.5 1.6 8.9 7.5 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 GBG69958.1 - 3.2 8.2 8.6 9.3 6.7 8.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4746 PF15928.5 GBG69958.1 - 4 6.8 7.1 7.6 5.9 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 GBG69958.1 - 4.1 6.6 5.1 8 5.7 5.1 1.4 1 0 0 1 1 1 0 NOA36 protein NDUF_B7 PF05676.13 GBG69959.1 - 8e-27 92.8 5.1 9.5e-27 92.5 5.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 GBG69959.1 - 0.011 15.7 1.1 0.015 15.3 1.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Chromo PF00385.24 GBG69960.1 - 1.8e-24 85.4 16.3 1.9e-08 34.1 0.1 3.9 4 0 0 4 4 4 3 Chromo (CHRromatin Organisation MOdifier) domain Ank_5 PF13857.6 GBG69960.1 - 4.1e-16 58.8 0.3 4.4e-11 42.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GBG69960.1 - 2.9e-13 50.2 0.1 9.1e-13 48.6 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GBG69960.1 - 1.5e-10 41.0 2.0 5.3e-06 26.7 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GBG69960.1 - 6.2e-10 39.4 0.1 0.0023 18.5 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Mtf2_C PF14061.6 GBG69960.1 - 8.6e-10 38.6 0.1 0.089 13.0 0.0 3.4 3 0 0 3 3 3 3 Polycomb-like MTF2 factor 2 Ank_3 PF13606.6 GBG69960.1 - 1.7e-09 37.1 0.6 6.4e-05 23.1 0.0 3.7 4 0 0 4 4 3 2 Ankyrin repeat DUF1918 PF08940.11 GBG69960.1 - 2.3e-05 23.9 2.6 0.37 10.5 0.1 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF1918) PWWP PF00855.17 GBG69960.1 - 9e-05 22.8 0.0 6.5 7.2 0.0 3.4 2 1 1 3 3 3 1 PWWP domain Tudor-knot PF11717.8 GBG69960.1 - 0.049 13.5 0.1 15 5.6 0.0 3.3 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain Chromo_shadow PF01393.19 GBG69960.1 - 0.15 12.2 0.6 9.1 6.5 0.0 3.0 3 0 0 3 3 3 0 Chromo shadow domain CENP-B_dimeris PF09026.10 GBG69960.1 - 0.28 11.6 5.4 0.76 10.2 5.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CT47 PF15623.6 GBG69961.1 - 0.0015 18.5 0.5 0.0023 17.9 0.5 1.3 1 0 0 1 1 1 1 Cancer/testis gene family 47 SnAC PF14619.6 GBG69961.1 - 2.3 8.9 6.9 0.19 12.3 0.6 2.1 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex Paf1 PF03985.13 GBG69961.1 - 5.6 5.9 6.1 7.8 5.4 6.1 1.1 1 0 0 1 1 1 0 Paf1 GIY-YIG PF01541.24 GBG69962.1 - 0.00046 20.4 0.0 0.0015 18.7 0.0 2.0 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG69963.1 - 0.00074 19.5 0.2 0.0013 18.7 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG69963.1 - 0.075 12.9 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Atrophin-1 PF03154.15 GBG69963.1 - 0.22 9.8 6.9 0.26 9.5 6.9 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF3464 PF11947.8 GBG69963.1 - 4.6 7.0 5.8 65 3.2 0.0 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF1682 PF07946.14 GBG69963.1 - 9.2 5.4 14.8 12 5.0 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-CCHC PF00098.23 GBG69964.1 - 0.023 14.8 1.7 0.039 14.0 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG69965.1 - 4.1e-16 59.2 0.0 7.8e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG69966.1 - 2.4e-10 40.6 1.4 9.7e-10 38.7 0.2 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG69966.1 - 0.091 13.1 1.2 0.18 12.2 0.4 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like rve PF00665.26 GBG69967.1 - 4.5e-09 36.5 0.0 9.2e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG69967.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain zf-CCHC PF00098.23 GBG69968.1 - 0.00013 21.9 6.0 0.00021 21.2 6.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG69968.1 - 0.013 15.4 5.4 0.019 14.8 5.4 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG69968.1 - 0.18 11.6 1.2 0.34 10.7 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 GBG69968.1 - 0.64 9.8 3.3 1.1 9.0 3.3 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger RT_RNaseH PF17917.1 GBG69969.1 - 6.5e-18 65.0 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG69969.1 - 9.3e-10 38.4 0.0 1.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Cwf_Cwc_15 PF04889.12 GBG69969.1 - 0.46 10.2 8.4 0.7 9.6 8.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG69969.1 - 0.48 9.8 9.3 0.57 9.5 9.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG69969.1 - 1.2 7.3 8.8 1.4 7.1 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Dimer_Tnp_hAT PF05699.14 GBG69970.1 - 7.6e-06 25.6 0.6 0.011 15.5 0.1 2.5 2 0 0 2 2 2 2 hAT family C-terminal dimerisation region Prefoldin_2 PF01920.20 GBG69970.1 - 0.017 15.1 1.4 0.017 15.1 1.4 3.2 3 0 0 3 3 3 0 Prefoldin subunit PriC PF07445.12 GBG69970.1 - 0.036 14.0 8.9 0.077 12.9 2.9 2.6 2 0 0 2 2 2 0 Primosomal replication protein priC DUF5320 PF17253.2 GBG69970.1 - 0.07 14.2 0.0 0.07 14.2 0.0 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5320) ToxN_toxin PF13958.6 GBG69970.1 - 0.095 12.9 6.3 3.6 7.8 0.3 2.3 2 0 0 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system DUF2681 PF10883.8 GBG69970.1 - 2.1 8.8 10.9 2.4 8.6 4.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) RVT_1 PF00078.27 GBG69971.1 - 7.8e-22 77.9 0.0 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG69971.1 - 5.6e-18 64.8 0.0 3.8e-13 49.3 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG69971.1 - 6.1e-16 58.3 0.1 6.1e-16 58.3 0.1 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG69971.1 - 2.3e-11 43.4 0.0 6.6e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG69971.1 - 3.5e-10 40.1 0.0 1.3e-09 38.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG69971.1 - 2.7e-09 37.3 0.0 3.1e-08 33.8 0.0 2.6 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG69971.1 - 0.00041 20.5 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG69971.1 - 0.019 15.6 0.0 0.045 14.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease HLH PF00010.26 GBG69972.1 - 0.00063 19.6 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UDG PF03167.19 GBG69973.1 - 6.5e-10 39.2 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily LRR_6 PF13516.6 GBG69973.1 - 1.9e-09 36.8 0.5 0.0015 18.4 0.1 4.2 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 GBG69973.1 - 0.097 13.1 0.1 23 5.6 0.1 2.6 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Rhodanese_C PF12368.8 GBG69974.1 - 2.9e-15 56.4 5.9 2.9e-15 56.4 5.9 3.4 4 1 0 4 4 4 1 Rhodanase C-terminal UPF0176_N PF17773.1 GBG69974.1 - 1.5e-14 54.1 0.0 4.4e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 GBG69974.1 - 6.9e-09 36.2 0.0 1.8e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S3Ae PF01015.18 GBG69975.1 - 8.4e-96 319.4 5.1 1e-95 319.1 5.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family MRP-L27 PF09809.9 GBG69975.1 - 0.052 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 PAP2_C PF14360.6 GBG69976.1 - 2.7e-15 56.7 0.1 2.7e-15 56.7 0.1 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 GBG69976.1 - 1.2e-05 25.2 1.4 1.2e-05 25.2 1.4 2.5 3 0 0 3 3 3 1 PAP2 superfamily PAP2 PF01569.21 GBG69976.1 - 0.00039 20.2 1.5 0.00039 20.2 1.5 3.1 4 0 0 4 4 4 1 PAP2 superfamily Ctf8 PF09696.10 GBG69977.1 - 1.9e-08 34.8 0.1 2.6e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Ctf8 Myb_DNA-bind_4 PF13837.6 GBG69978.1 - 7.6e-05 23.0 0.2 0.00015 22.1 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG69978.1 - 0.0055 16.7 0.3 0.015 15.3 0.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PH PF00169.29 GBG69979.1 - 0.016 15.7 0.0 0.055 14.0 0.0 1.9 2 0 0 2 2 2 0 PH domain Uds1 PF15456.6 GBG69979.1 - 0.039 14.1 0.4 0.093 12.9 0.4 1.6 1 0 0 1 1 1 0 Up-regulated During Septation YabA PF06156.13 GBG69979.1 - 0.083 13.5 0.1 0.19 12.4 0.1 1.6 1 0 0 1 1 1 0 Initiation control protein YabA DUF2389 PF09493.10 GBG69981.1 - 4e-17 62.6 3.7 6.7e-17 61.9 3.7 1.4 1 0 0 1 1 1 1 Tryptophan-rich protein (DUF2389) zf-C4pol PF14260.6 GBG69981.1 - 2 8.9 6.4 4.9 7.7 0.7 2.6 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Aminotran_1_2 PF00155.21 GBG69983.1 - 3e-65 220.8 0.0 3.7e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II BUD22 PF09073.10 GBG69983.1 - 0.24 10.7 9.4 0.34 10.2 9.4 1.1 1 0 0 1 1 1 0 BUD22 Radial_spoke PF04712.12 GBG69983.1 - 0.26 10.2 12.8 0.42 9.5 12.8 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Tim54 PF11711.8 GBG69983.1 - 0.28 9.9 4.2 0.45 9.2 4.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SDA1 PF05285.12 GBG69983.1 - 0.43 10.0 15.1 0.12 11.8 12.1 1.5 2 0 0 2 2 2 0 SDA1 DUF3464 PF11947.8 GBG69983.1 - 0.46 10.2 1.4 0.99 9.1 1.4 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EIIBC-GUT_N PF03612.14 GBG69983.1 - 4 7.2 5.4 7 6.3 5.4 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FAM176 PF14851.6 GBG69983.1 - 5.3 6.7 10.6 2.8 7.6 8.5 1.6 2 0 0 2 2 2 0 FAM176 family MscS_TM PF12794.7 GBG69983.1 - 7.8 5.2 7.7 12 4.6 7.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Peptidase_M20 PF01546.28 GBG69984.1 - 2.8e-31 108.8 0.3 4e-31 108.3 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 GBG69984.1 - 6.6e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 HTH_31 PF13560.6 GBG69984.1 - 0.088 13.2 0.1 1.7 9.1 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain RVT_1 PF00078.27 GBG69985.1 - 2.5e-24 86.0 0.1 4.1e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) R3H-assoc PF13902.6 GBG69985.1 - 0.31 11.4 1.6 1.4 9.3 0.1 2.2 2 0 0 2 2 2 0 R3H-associated N-terminal domain DUF4687 PF15747.5 GBG69985.1 - 0.37 11.3 3.1 13 6.3 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) zf-CCHC PF00098.23 GBG69986.1 - 0.00012 21.9 3.8 0.00026 20.9 3.8 1.6 1 0 0 1 1 1 1 Zinc knuckle AAA_23 PF13476.6 GBG69986.1 - 0.0055 17.2 3.5 0.012 16.1 3.5 1.6 1 0 0 1 1 1 1 AAA domain zf-CCHC_2 PF13696.6 GBG69986.1 - 0.3 10.9 3.2 0.66 9.8 3.2 1.6 1 0 0 1 1 1 0 Zinc knuckle ArAE_2_N PF10337.9 GBG69986.1 - 0.59 9.1 6.8 0.89 8.5 6.8 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal gag-asp_proteas PF13975.6 GBG69987.1 - 0.00013 22.5 0.6 0.00038 21.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG69987.1 - 0.00035 21.2 0.2 0.0012 19.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RXLR PF16810.5 GBG69987.1 - 1.7 9.1 4.3 17 5.9 0.1 2.8 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Guanylate_kin PF00625.21 GBG69988.1 - 6.2e-37 127.0 0.2 7.1e-37 126.8 0.2 1.0 1 0 0 1 1 1 1 Guanylate kinase Peptidase_S24 PF00717.23 GBG69988.1 - 0.0076 16.2 0.2 7.1 6.7 0.0 3.1 1 1 1 2 2 2 1 Peptidase S24-like AAA_16 PF13191.6 GBG69988.1 - 0.016 15.6 0.0 0.017 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 GBG69988.1 - 0.017 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase MobB PF03205.14 GBG69988.1 - 0.084 12.8 0.2 4.7 7.1 0.0 2.4 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 GBG69988.1 - 0.094 13.3 0.0 0.35 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain Phage_integrase PF00589.22 GBG69989.1 - 2.2e-06 27.6 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family MORN PF02493.20 GBG69990.1 - 5.3e-18 63.8 13.1 2.2e-09 36.7 0.2 4.5 4 0 0 4 4 4 4 MORN repeat UQ_con PF00179.26 GBG69992.1 - 4.2e-31 107.5 0.0 4.7e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 GBG69992.1 - 0.055 13.3 0.2 0.097 12.5 0.2 1.4 1 1 0 1 1 1 0 UEV domain YjcZ PF13990.6 GBG69992.1 - 0.091 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 YjcZ-like protein Tme5_EGF_like PF09064.10 GBG69992.1 - 0.47 10.4 3.6 0.21 11.5 0.7 1.9 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like mTERF PF02536.14 GBG69993.1 - 5.5e-48 163.5 1.4 3.5e-30 105.0 0.0 2.2 1 1 1 2 2 2 2 mTERF RR_TM4-6 PF06459.12 GBG69993.1 - 0.35 10.7 5.9 0.62 9.8 5.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 GBG69993.1 - 1.1 8.2 8.1 1.9 7.4 8.1 1.2 1 0 0 1 1 1 0 Paf1 DDRGK PF09756.9 GBG69993.1 - 2.1 7.9 15.1 3.9 7.0 15.1 1.3 1 0 0 1 1 1 0 DDRGK domain FAM176 PF14851.6 GBG69993.1 - 2.2 8.0 7.4 5 6.8 7.4 1.6 1 0 0 1 1 1 0 FAM176 family RTX_C PF08339.10 GBG69993.1 - 9.7 6.2 9.3 29 4.7 0.0 2.5 2 0 0 2 2 2 0 RTX C-terminal domain mTERF PF02536.14 GBG69994.1 - 6e-51 173.2 2.8 1.6e-33 116.0 0.0 2.2 1 1 1 2 2 2 2 mTERF RR_TM4-6 PF06459.12 GBG69994.1 - 0.35 10.7 5.9 0.62 9.8 5.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 GBG69994.1 - 1.1 8.1 8.1 1.9 7.4 8.1 1.2 1 0 0 1 1 1 0 Paf1 DDRGK PF09756.9 GBG69994.1 - 2.1 7.9 15.1 4 7.0 15.1 1.3 1 0 0 1 1 1 0 DDRGK domain FAM176 PF14851.6 GBG69994.1 - 2.2 7.9 7.4 5.1 6.8 7.4 1.5 1 0 0 1 1 1 0 FAM176 family RTX_C PF08339.10 GBG69994.1 - 9.9 6.2 9.3 29 4.7 0.0 2.5 2 0 0 2 2 2 0 RTX C-terminal domain TPR_2 PF07719.17 GBG69995.1 - 5.2e-12 44.9 4.3 0.00034 20.5 1.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat Lactamase_B PF00753.27 GBG69995.1 - 2e-11 44.3 0.2 1.3e-10 41.6 0.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_1 PF00515.28 GBG69995.1 - 3.9e-10 39.1 4.9 0.00044 20.0 1.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG69995.1 - 4.2e-08 33.4 0.7 0.00031 21.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG69995.1 - 2.8e-06 27.1 1.8 0.43 10.9 0.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG69995.1 - 0.00025 20.8 3.6 4.4 7.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 GBG69995.1 - 0.0026 17.8 0.1 0.022 14.8 0.1 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 GBG69995.1 - 0.0032 17.4 0.1 0.47 10.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 GBG69995.1 - 0.0061 16.1 0.1 0.026 14.0 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TPR_16 PF13432.6 GBG69995.1 - 0.008 16.8 2.2 0.32 11.7 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG69995.1 - 0.027 14.2 3.1 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 GBG69995.1 - 0.03 15.1 1.7 2.2 9.3 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG69995.1 - 0.051 14.0 0.2 11 6.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG69996.1 - 3e-12 45.6 4.3 0.00027 20.8 1.5 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat Lactamase_B PF00753.27 GBG69996.1 - 1.2e-11 45.0 0.2 9.2e-11 42.1 0.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_1 PF00515.28 GBG69996.1 - 2.3e-10 39.8 4.9 0.00036 20.2 1.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG69996.1 - 2.9e-08 33.9 0.7 0.00024 21.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG69996.1 - 1.6e-06 27.8 1.8 0.35 11.2 0.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG69996.1 - 0.00015 21.5 3.6 3.6 7.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 GBG69996.1 - 0.0019 18.2 0.2 0.017 15.2 0.1 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 GBG69996.1 - 0.0025 17.7 0.1 0.39 10.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG69996.1 - 0.0034 18.0 1.6 0.26 12.0 0.2 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 GBG69996.1 - 0.0043 16.6 0.1 0.019 14.5 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TPR_14 PF13428.6 GBG69996.1 - 0.018 15.8 1.6 1.7 9.6 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GBG69996.1 - 0.018 14.7 3.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 GBG69996.1 - 0.077 13.4 1.3 8.6 7.0 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat CbiX PF01903.17 GBG69997.1 - 3.5e-25 88.4 0.0 5.2e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 CbiX RraA-like PF03737.15 GBG69998.1 - 9.5e-44 149.2 2.5 1.1e-43 149.0 2.5 1.0 1 0 0 1 1 1 1 Aldolase/RraA Nudix_hydro PF18290.1 GBG69999.1 - 3.2e-25 87.9 0.0 6e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 GBG69999.1 - 3.3e-20 72.5 0.1 7.1e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain RNase_T PF00929.24 GBG69999.1 - 2.2e-10 41.3 0.0 4.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Myb_DNA-bind_4 PF13837.6 GBG70000.1 - 9.6e-11 41.9 1.1 1.7e-10 41.2 1.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG70000.1 - 0.0066 16.7 0.3 0.013 15.7 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70000.1 - 0.021 15.1 0.7 0.039 14.3 0.7 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG70000.1 - 0.18 11.9 1.6 0.34 11.0 1.6 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3693 PF12472.8 GBG70000.1 - 0.89 9.3 3.1 0.35 10.6 0.2 1.8 2 0 0 2 2 2 0 Phage related protein RVT_1 PF00078.27 GBG70001.1 - 1.2e-34 119.8 0.1 1.8e-34 119.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70001.1 - 1.2e-28 99.1 0.0 5.1e-28 97.1 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70001.1 - 1.7e-27 95.7 0.1 6.3e-27 93.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70001.1 - 1.8e-17 63.2 1.2 4e-17 62.1 1.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG70001.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70001.1 - 1.3e-05 25.8 0.0 3.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70001.1 - 0.00031 21.2 0.1 0.0021 18.6 0.0 2.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG70001.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG70001.1 - 0.003 17.8 0.6 0.012 15.8 0.1 2.4 3 0 0 3 3 3 1 H2C2 zinc finger DUF4392 PF14336.6 GBG70001.1 - 0.042 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) TssO PF17561.2 GBG70001.1 - 0.89 9.6 7.3 8.4 6.5 7.2 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssO REV PF00424.18 GBG70001.1 - 1.8 8.6 4.4 1.1 9.3 0.7 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Tweety PF04906.13 GBG70002.1 - 1.7e-06 27.0 0.2 0.0047 15.6 0.5 2.2 2 0 0 2 2 2 2 Tweety DUF2207 PF09972.9 GBG70002.1 - 0.0049 15.7 5.6 0.23 10.2 0.2 2.2 1 1 0 2 2 2 2 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 GBG70002.1 - 0.0063 16.2 6.8 0.082 12.6 1.1 2.9 3 0 0 3 3 3 2 Tetraspanin family ApoLp-III PF07464.11 GBG70002.1 - 0.033 14.3 3.8 3.1 7.9 1.1 2.8 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Chordopox_E11 PF06138.12 GBG70002.1 - 0.085 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus E11 protein ETRAMP PF09716.10 GBG70002.1 - 0.12 12.4 0.0 1.6 8.9 0.0 2.5 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Wzy_C PF04932.15 GBG70002.1 - 0.99 9.0 9.4 0.12 12.0 0.6 3.0 3 1 1 4 4 4 0 O-Antigen ligase zf-RING_2 PF13639.6 GBG70003.1 - 6.1e-08 32.9 8.7 1.2e-07 31.9 8.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG70003.1 - 1.7e-07 31.0 4.8 2.8e-07 30.3 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG70003.1 - 4e-07 29.9 2.9 7.4e-07 29.1 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GBG70003.1 - 6e-07 29.7 7.5 1.4e-06 28.5 7.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain CUE PF02845.16 GBG70003.1 - 5e-06 26.1 0.0 4.5e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 CUE domain zf-C3HC4_3 PF13920.6 GBG70003.1 - 7.9e-05 22.4 5.0 0.00013 21.7 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG70003.1 - 0.00012 21.7 3.6 0.00027 20.6 3.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 GBG70003.1 - 0.00013 22.0 5.8 0.00029 20.8 5.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GBG70003.1 - 0.00028 20.7 9.5 0.00048 19.9 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG70003.1 - 0.0059 16.5 4.5 0.013 15.4 4.5 1.5 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG70003.1 - 0.0089 15.9 5.3 0.017 15.0 5.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GBG70003.1 - 0.014 15.5 7.8 0.024 14.8 7.8 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 GBG70003.1 - 0.052 13.7 4.0 0.12 12.5 4.0 1.6 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 GBG70003.1 - 0.07 12.8 6.9 0.18 11.5 6.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 GBG70003.1 - 0.096 12.6 4.2 0.27 11.1 4.2 1.8 1 1 0 1 1 1 0 PHD-finger PAP_central PF04928.17 GBG70005.1 - 1.6e-109 364.7 0.0 2.2e-109 364.2 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GBG70005.1 - 2.8e-20 72.6 0.6 5.7e-13 48.8 0.1 2.8 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GBG70005.1 - 2.6e-12 46.8 0.0 2e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain DUF2722 PF10846.8 GBG70005.1 - 0.0085 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Nrap_D2 PF17403.2 GBG70005.1 - 0.02 14.7 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Spt20 PF12090.8 GBG70005.1 - 0.25 10.9 5.6 0.43 10.2 5.6 1.4 1 0 0 1 1 1 0 Spt20 family FTZ PF03867.14 GBG70005.1 - 0.44 10.1 1.5 0.73 9.3 1.5 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region PAP_central PF04928.17 GBG70006.1 - 4.2e-77 258.5 0.0 7.7e-77 257.6 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PP2C PF00481.21 GBG70006.1 - 5e-43 147.6 0.0 1e-42 146.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C RT_RNaseH_2 PF17919.1 GBG70006.1 - 6.6e-34 115.9 0.0 1.7e-33 114.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70006.1 - 5.5e-29 101.3 0.0 1.5e-28 99.8 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70006.1 - 8.4e-29 99.9 0.4 2.7e-28 98.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase PAP_RNA-bind PF04926.15 GBG70006.1 - 7.6e-05 22.4 0.0 0.0045 16.6 0.0 2.6 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain PAP_central PF04928.17 GBG70007.1 - 9.1e-106 352.4 0.0 1.2e-105 352.0 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GBG70007.1 - 1.3e-19 70.5 0.0 4.8e-12 45.8 0.1 2.7 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GBG70007.1 - 2.1e-11 43.9 0.0 5.4e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 GBG70007.1 - 0.02 14.7 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Rib_recp_KP_reg PF05104.12 GBG70007.1 - 0.055 14.5 10.6 0.097 13.7 10.6 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Kinesin_assoc PF16183.5 GBG70007.1 - 4.6 7.4 4.9 1 9.4 0.1 2.1 2 1 0 2 2 2 0 Kinesin-associated Tir_receptor_N PF07490.11 GBG70008.1 - 0.086 12.7 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus RecA_dep_nuc PF16786.5 GBG70008.1 - 0.1 12.8 0.2 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease SLC12 PF03522.15 GBG70010.1 - 1.3 8.0 10.2 1.6 7.7 10.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Sucrose_synth PF00862.19 GBG70011.1 - 8.6e-249 826.4 0.0 1e-248 826.1 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG70011.1 - 1.1e-32 113.0 0.0 2.2e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG70011.1 - 8.1e-13 49.0 0.0 3e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG70011.1 - 2.3e-06 27.9 0.0 7e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2095 PF09868.9 GBG70011.1 - 0.16 12.0 0.0 0.71 9.9 0.0 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) CbiA PF01656.23 GBG70011.1 - 0.21 11.6 0.0 5.6 7.0 0.0 2.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNase_T PF00929.24 GBG70013.1 - 7.2e-11 42.9 0.0 1.4e-10 42.0 0.0 1.4 2 0 0 2 2 2 1 Exonuclease SUIM_assoc PF16619.5 GBG70013.1 - 6.1 7.0 12.3 14 5.9 12.3 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 NUDIX PF00293.28 GBG70014.1 - 2.7e-05 24.2 0.5 3.3e-05 23.9 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain IFR3_antag PF14754.6 GBG70014.1 - 0.0005 19.4 0.1 0.00065 19.0 0.1 1.1 1 0 0 1 1 1 1 Papain-like auto-proteinase Catalase PF00199.19 GBG70016.1 - 9.3e-174 578.0 0.0 1.1e-173 577.8 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GBG70016.1 - 3.6e-17 62.3 0.0 7e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive CBM64 PF18666.1 GBG70017.1 - 0.013 15.6 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 64 Dimer_Tnp_hAT PF05699.14 GBG70017.1 - 0.04 13.7 0.2 0.075 12.8 0.2 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG70018.1 - 3.6e-30 104.8 0.4 5.4e-30 104.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG70018.1 - 0.0065 16.2 0.1 0.02 14.7 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG70019.1 - 1.6e-19 70.3 0.0 2.3e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) HSP70 PF00012.20 GBG70021.1 - 1.9e-145 485.4 0.0 3.7e-145 484.5 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG70021.1 - 1.6e-12 46.9 2.7 2.7e-06 26.5 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 GBG70021.1 - 7.2e-05 23.2 0.0 0.46 10.9 0.0 2.8 2 1 0 2 2 2 2 Cell division protein FtsA StbA PF06406.11 GBG70021.1 - 0.1 11.8 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 StbA protein F-box-like PF12937.7 GBG70025.1 - 6.6e-07 29.1 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG70025.1 - 0.033 14.1 0.7 0.12 12.3 0.0 2.3 3 0 0 3 3 3 0 F-box domain Big_2 PF02368.18 GBG70026.1 - 1.2e-16 60.3 15.9 5.9e-05 22.9 0.0 7.0 8 0 0 8 8 8 4 Bacterial Ig-like domain (group 2) p450 PF00067.22 GBG70028.1 - 4e-71 240.1 0.1 2.9e-70 237.3 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.20 GBG70028.1 - 0.0082 14.4 0.0 0.012 13.8 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein HMG_box PF00505.19 GBG70028.1 - 0.056 13.9 0.2 0.13 12.7 0.2 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box p450 PF00067.22 GBG70029.1 - 1.4e-80 271.3 0.1 1.1e-40 139.8 0.3 2.8 2 1 0 2 2 2 2 Cytochrome P450 Rad10 PF03834.14 GBG70030.1 - 7.7e-43 145.1 0.2 1.1e-42 144.6 0.2 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 GBG70030.1 - 3.2e-07 30.9 0.0 1e-06 29.2 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 GBG70030.1 - 2.3e-05 24.4 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 GBG70030.1 - 0.0096 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HRDC PF00570.23 GBG70030.1 - 0.024 14.6 0.0 0.069 13.1 0.0 1.7 2 0 0 2 2 2 0 HRDC domain HC2 PF07382.11 GBG70031.1 - 1.4 9.0 18.1 4.8 7.2 18.0 1.8 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DUF4187 PF13821.6 GBG70032.1 - 4e-16 58.5 2.3 1e-15 57.2 2.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 GBG70032.1 - 1.4e-14 53.7 2.7 3.1e-14 52.6 2.7 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GBG70032.1 - 3.1e-07 30.4 3.0 4.1e-07 30.0 0.9 2.4 1 1 1 2 2 2 1 G-patch domain DUF2724 PF10893.8 GBG70033.1 - 1.3 8.9 5.8 0.43 10.4 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2724) NRDE-2 PF08424.10 GBG70034.1 - 2.3e-72 243.8 17.5 2.3e-72 243.8 17.5 3.3 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 GBG70034.1 - 4.7e-05 23.9 1.8 9.9 7.3 0.0 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat p450 PF00067.22 GBG70035.1 - 3.6e-83 279.9 0.0 1.1e-42 146.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 TetR_C_28 PF17937.1 GBG70035.1 - 0.85 10.1 2.9 36 4.9 0.1 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PUF PF00806.19 GBG70036.1 - 1.1e-10 40.6 0.0 1.2 9.0 0.0 7.8 9 0 0 9 9 9 4 Pumilio-family RNA binding repeat Integrase_H2C2 PF17921.1 GBG70037.1 - 4.3e-16 58.8 0.1 9.5e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-RING_2 PF13639.6 GBG70038.1 - 2.3e-11 43.8 8.9 2.3e-11 43.8 8.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 GBG70038.1 - 1.7e-08 34.0 6.4 4.2e-08 32.8 6.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GBG70038.1 - 1.1e-07 32.0 5.7 2.2e-07 31.1 5.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GBG70038.1 - 1.8e-07 30.9 9.2 3.6e-07 29.9 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG70038.1 - 8.1e-06 25.6 8.2 8.1e-06 25.6 8.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG70038.1 - 0.0006 19.7 6.5 0.0006 19.7 6.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GBG70038.1 - 0.0006 19.6 6.6 0.0006 19.6 6.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG70038.1 - 0.0036 17.1 7.4 0.0077 16.1 7.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GBG70038.1 - 0.022 14.8 4.9 0.06 13.4 4.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GBG70038.1 - 2.5 8.2 12.5 0.047 13.7 4.7 2.1 2 1 1 3 3 3 0 RING-type zinc-finger RRP7 PF12923.7 GBG70039.1 - 1.3e-29 102.7 6.0 1.3e-29 102.7 6.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain PBP_sp32 PF07222.12 GBG70039.1 - 0.17 11.3 1.3 0.3 10.5 1.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CAML PF14963.6 GBG70039.1 - 0.33 11.1 4.4 1.4 9.0 0.5 2.0 1 1 1 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF4407 PF14362.6 GBG70039.1 - 5.2 6.3 9.7 6.8 6.0 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cation_ATPase_C PF00689.21 GBG70040.1 - 1.5 8.5 6.7 0.12 12.0 1.5 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus RabGAP-TBC PF00566.18 GBG70041.1 - 1.5e-32 113.0 0.0 2.1e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2946 PF11162.8 GBG70041.1 - 9.2 7.0 9.5 22 5.8 9.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF2052 PF09747.9 GBG70042.1 - 0.047 13.8 14.4 0.051 13.7 14.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RPN2_C PF18004.1 GBG70042.1 - 0.4 10.6 7.7 0.42 10.5 7.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CPSF100_C PF13299.6 GBG70042.1 - 0.64 10.2 5.8 0.7 10.1 5.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Mpp10 PF04006.12 GBG70042.1 - 0.81 8.0 17.7 0.78 8.1 17.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Paf1 PF03985.13 GBG70042.1 - 0.91 8.4 21.6 0.93 8.4 21.6 1.1 1 0 0 1 1 1 0 Paf1 SURF2 PF05477.11 GBG70042.1 - 1.5 8.5 11.9 1.6 8.3 11.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PI3K_1B_p101 PF10486.9 GBG70042.1 - 1.6 6.4 5.0 1.7 6.3 5.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RR_TM4-6 PF06459.12 GBG70042.1 - 1.6 8.5 9.0 1.6 8.5 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP90 PF00183.18 GBG70042.1 - 1.7 7.5 9.3 1.6 7.5 9.3 1.1 1 0 0 1 1 1 0 Hsp90 protein Nop53 PF07767.11 GBG70042.1 - 1.7 8.0 14.3 1.6 8.0 14.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Usp PF00582.26 GBG70042.1 - 2.5 8.6 5.9 3.1 8.3 5.9 1.1 1 0 0 1 1 1 0 Universal stress protein family SDA1 PF05285.12 GBG70042.1 - 2.7 7.4 22.5 2.9 7.3 22.5 1.1 1 0 0 1 1 1 0 SDA1 Connexin PF00029.19 GBG70042.1 - 3.5 7.3 4.6 3.4 7.4 4.6 1.1 1 0 0 1 1 1 0 Connexin Nop14 PF04147.12 GBG70042.1 - 3.8 5.6 21.9 3.8 5.6 21.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG70042.1 - 4.4 5.5 17.5 4.9 5.3 17.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DARPP-32 PF05395.12 GBG70042.1 - 8.4 6.6 16.4 9.6 6.4 16.4 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 PCI PF01399.27 GBG70043.1 - 2.3e-17 63.4 0.0 6.7e-17 61.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 GBG70043.1 - 5.2e-12 45.7 4.3 1.1e-11 44.6 4.3 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Adeno_VII PF03228.14 GBG70043.1 - 0.019 15.6 0.1 0.044 14.4 0.1 1.6 1 0 0 1 1 1 0 Adenoviral core protein VII DUF4376 PF14301.6 GBG70043.1 - 0.23 11.8 5.2 1 9.8 0.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4376) WD40 PF00400.32 GBG70045.1 - 3.2e-26 91.1 20.7 1.4e-06 28.9 3.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG70045.1 - 1e-06 29.0 0.0 2.9 8.3 0.0 5.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Marek_SORF3 PF07153.11 GBG70045.1 - 0.0052 16.2 0.1 0.018 14.4 0.1 1.8 2 0 0 2 2 2 1 Marek's disease-like virus SORF3 protein Peptidase_S41 PF03572.18 GBG70046.1 - 3.9e-48 163.1 0.0 6.4e-48 162.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GBG70046.1 - 9.4e-15 54.2 0.5 2.2e-14 53.0 0.5 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GBG70046.1 - 4.2e-12 46.3 0.1 8.4e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GBG70046.1 - 4e-10 39.9 0.0 1.4e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Tricorn_C1 PF14684.6 GBG70046.1 - 6e-05 23.0 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 Tricorn protease C1 domain Tricorn_PDZ PF14685.6 GBG70046.1 - 0.014 15.3 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain CDC45 PF02724.14 GBG70047.1 - 3.2 5.9 11.1 3.8 5.7 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM221 PF14753.6 GBG70048.1 - 6.8e-28 97.6 20.3 3.2e-23 82.3 10.6 2.1 2 0 0 2 2 2 2 Protein FAM221A/B Totivirus_coat PF05518.11 GBG70048.1 - 1.2 7.1 2.7 1.4 6.8 2.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein Cupin_3 PF05899.12 GBG70049.1 - 8.4e-18 63.8 0.4 1.6e-17 62.9 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 GBG70049.1 - 0.0058 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 GBG70049.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ VPS13 PF16908.5 GBG70050.1 - 2.5e-60 204.2 1.6 8.9e-37 127.1 0.3 4.3 5 0 0 5 5 5 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 GBG70050.1 - 2.8e-35 121.9 0.0 3e-31 108.7 0.0 4.0 4 1 0 4 4 4 2 Repeating coiled region of VPS13 RT_RNaseH_2 PF17919.1 GBG70050.1 - 8.6e-32 109.2 0.0 1.9e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chorein_N PF12624.7 GBG70050.1 - 1.2e-29 102.7 0.1 1.2e-29 102.7 0.1 2.5 3 0 0 3 3 1 1 N-terminal region of Chorein or VPS13 RT_RNaseH PF17917.1 GBG70050.1 - 1e-26 93.3 0.0 2.1e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Vps62 PF06101.11 GBG70050.1 - 2.9e-24 85.3 0.0 5e-12 44.9 0.0 2.5 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 SHR-BD PF06650.12 GBG70050.1 - 6e-18 65.2 0.0 3e-16 59.6 0.0 2.8 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Integrase_H2C2 PF17921.1 GBG70050.1 - 2.7e-16 59.4 0.0 6.8e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70050.1 - 1.6e-12 47.6 0.1 5e-12 46.1 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain Pex24p PF06398.11 GBG70050.1 - 1.1e-08 34.5 2.1 2.1e-08 33.6 2.1 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin ATG_C PF09333.11 GBG70050.1 - 8.5e-07 29.2 0.0 4.7e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 GBG70050.1 - 1.9e-06 27.8 4.9 0.015 15.1 0.5 3.7 3 1 1 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal C2 PF00168.30 GBG70050.1 - 1.8e-05 24.9 0.0 6.6e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 C2 domain PH PF00169.29 GBG70050.1 - 0.076 13.5 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 PH domain PPR_2 PF13041.6 GBG70051.1 - 3.1e-61 203.4 11.1 1.1e-08 35.2 0.0 14.4 7 3 9 16 16 16 11 PPR repeat family PPR PF01535.20 GBG70051.1 - 8.2e-46 151.1 30.2 5.2e-07 29.5 0.0 14.5 15 0 0 15 15 15 11 PPR repeat PPR_3 PF13812.6 GBG70051.1 - 7.2e-39 131.7 0.0 3.6e-10 39.8 0.0 10.5 5 3 7 12 12 12 8 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG70051.1 - 7.2e-35 120.3 10.5 1.3e-14 54.1 0.1 6.6 2 1 5 7 7 7 6 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GBG70051.1 - 3.1e-25 87.6 20.8 2e-06 27.4 0.0 11.8 13 0 0 13 13 13 5 PPR repeat TPR_7 PF13176.6 GBG70051.1 - 0.0021 17.9 1.5 16 5.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG70051.1 - 0.0046 17.7 10.8 56 4.9 0.1 8.3 7 2 2 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG70051.1 - 0.039 14.6 0.0 23 5.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG70051.1 - 3.2 7.7 5.9 49 4.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 GBG70052.1 - 2.2e-16 61.1 7.6 2.2e-16 61.1 7.6 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG70052.1 - 1.7e-13 50.8 0.1 4.8e-13 49.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 GBG70052.1 - 7.4e-07 29.5 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 GBG70052.1 - 1.4e-05 24.5 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GBG70052.1 - 0.012 15.3 0.1 0.073 12.8 0.0 1.9 1 1 1 2 2 2 0 PGAP1-like protein RVT_1 PF00078.27 GBG70053.1 - 5.8e-33 114.3 0.0 1.1e-32 113.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70053.1 - 6.8e-16 58.1 0.1 2.4e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG70053.1 - 4.3e-13 49.5 0.0 1.7e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG70053.1 - 0.018 15.2 0.0 0.047 13.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 GBG70053.1 - 0.095 12.5 0.0 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain Adaptin_binding PF10199.9 GBG70053.1 - 2.8 8.5 7.8 3.5 8.2 5.7 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RT_RNaseH_2 PF17919.1 GBG70054.1 - 8.1e-23 80.4 0.0 1.7e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70054.1 - 2.6e-22 79.1 0.0 7.3e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70054.1 - 1.1e-17 63.9 0.4 2.4e-17 62.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70054.1 - 3.1e-17 62.8 0.0 9.6e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG70054.1 - 8.6e-11 41.8 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG70054.1 - 0.00077 19.6 0.2 0.0018 18.5 0.2 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Cytotoxic PF09000.10 GBG70054.1 - 2.6 8.5 4.9 3.5 8.0 0.1 2.9 3 0 0 3 3 3 0 Cytotoxic DUF5427 PF10310.9 GBG70055.1 - 0.06 12.3 12.5 0.071 12.1 12.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 GBG70055.1 - 0.22 10.3 12.4 0.23 10.2 12.4 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GBG70055.1 - 0.89 8.7 5.9 1.1 8.5 5.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 GBG70055.1 - 4.2 6.1 9.9 4.7 6.0 9.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4813 PF16072.5 GBG70055.1 - 8.9 5.9 11.9 11 5.6 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) DDE_Tnp_4 PF13359.6 GBG70057.1 - 6.6e-32 110.4 0.0 6.5e-31 107.1 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70057.1 - 1.2e-18 67.4 0.0 2.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70057.1 - 0.012 15.3 1.4 6.1 6.4 0.1 3.0 3 0 0 3 3 3 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG70057.1 - 0.025 14.9 0.8 0.25 11.7 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG70059.1 - 8.4e-08 32.5 0.7 5.2e-07 30.0 0.3 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain PTR2 PF00854.21 GBG70060.1 - 2.6e-100 336.0 2.2 4.7e-99 331.9 2.2 2.0 1 1 0 1 1 1 1 POT family DUF2570 PF10828.8 GBG70061.1 - 1.1 9.1 3.0 2 8.3 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF963 PF06131.11 GBG70062.1 - 0.14 11.6 0.1 0.14 11.6 0.1 3.8 3 1 1 4 4 4 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) UFD1 PF03152.14 GBG70063.1 - 6.5e-36 123.4 0.0 2.9e-21 75.7 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 GCN5L1 PF06320.13 GBG70063.1 - 1.6e-31 108.8 2.8 1.6e-31 108.8 2.8 2.1 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) zf-C2H2_4 PF13894.6 GBG70063.1 - 0.0077 17.0 19.2 0.91 10.5 0.0 6.2 6 1 1 7 7 7 2 C2H2-type zinc finger zf-Di19 PF05605.12 GBG70063.1 - 0.056 13.7 9.0 6.7 7.1 0.1 5.0 6 0 0 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 GBG70063.1 - 1.1 9.8 6.5 3.4 8.2 0.2 3.7 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 GBG70063.1 - 1.3 8.9 5.3 2 8.3 0.4 3.0 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) TF_Zn_Ribbon PF08271.12 GBG70063.1 - 8.5 6.0 18.7 1.8 8.2 0.1 6.1 7 0 0 7 7 7 0 TFIIB zinc-binding zf-TRAF PF02176.18 GBG70063.1 - 8.7 7.1 27.1 0.078 13.7 3.0 4.1 3 1 2 5 5 5 0 TRAF-type zinc finger AMPK1_CBM PF16561.5 GBG70064.1 - 1.1e-31 108.9 0.1 1.7e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 GBG70064.1 - 6.3e-22 77.6 3.0 1.2e-21 76.8 3.0 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain Bromodomain PF00439.25 GBG70066.1 - 8.9e-17 60.9 0.0 1.4e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain DUF2064 PF09837.9 GBG70066.1 - 6.6e-10 38.9 0.1 2.1e-08 34.0 0.0 3.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2064) Myb_DNA-binding PF00249.31 GBG70066.1 - 0.00026 21.1 0.0 0.00081 19.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SDA1 PF05285.12 GBG70067.1 - 0.0095 15.4 25.3 0.011 15.1 25.3 1.0 1 0 0 1 1 1 1 SDA1 Autophagy_N PF03986.13 GBG70067.1 - 0.03 14.3 6.1 0.051 13.5 6.0 1.5 1 1 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF3807 PF12720.7 GBG70067.1 - 0.051 13.8 13.2 0.071 13.4 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Cwf_Cwc_15 PF04889.12 GBG70067.1 - 3 7.5 19.5 4.2 7.0 19.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG70067.1 - 4 5.6 21.1 6.4 4.9 21.1 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG70067.1 - 4.3 6.6 26.8 4.8 6.4 26.8 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG70067.1 - 5.2 5.2 27.2 6.7 4.8 27.2 1.1 1 0 0 1 1 1 0 Nop14-like family DEK_C PF08766.11 GBG70068.1 - 0.034 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain Nop14 PF04147.12 GBG70069.1 - 6.1 4.9 20.0 14 3.8 20.0 1.5 1 0 0 1 1 1 0 Nop14-like family zf-CCHC_3 PF13917.6 GBG70070.1 - 0.007 16.3 1.7 0.014 15.3 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF1478 PF07349.11 GBG70070.1 - 0.015 15.2 0.2 0.03 14.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1478) rve PF00665.26 GBG70070.1 - 0.021 15.0 0.0 0.082 13.1 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain zf-CCHC PF00098.23 GBG70070.1 - 0.23 11.6 4.6 0.44 10.7 4.6 1.5 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 GBG70071.1 - 0.0043 16.8 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG70071.1 - 0.012 16.2 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1478 PF07349.11 GBG70071.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) zf-CCHC_3 PF13917.6 GBG70071.1 - 0.02 14.8 3.3 0.047 13.7 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1758 PF05585.12 GBG70071.1 - 0.094 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG70071.1 - 0.1 13.3 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG70071.1 - 3.2 8.0 9.5 0.47 10.6 4.6 2.2 2 0 0 2 2 2 0 Zinc knuckle UPF0051 PF01458.17 GBG70072.1 - 4e-63 213.0 0.2 5.3e-63 212.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) UPF0051 PF01458.17 GBG70073.1 - 1e-62 211.7 0.2 1.3e-62 211.3 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Utp21 PF04192.12 GBG70074.1 - 1.4e-56 191.7 0.2 1.4e-56 191.7 0.2 1.7 1 1 1 2 2 2 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 GBG70074.1 - 2.8e-27 94.4 8.7 7.7e-08 32.9 0.1 10.6 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG70074.1 - 1.1e-16 60.8 0.0 0.00019 21.7 0.0 7.5 2 2 6 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GBG70074.1 - 0.016 13.8 0.1 0.11 11.0 0.2 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 GBG70074.1 - 0.024 13.6 0.0 6.6 5.6 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 GBG70074.1 - 0.077 12.0 0.1 0.74 8.8 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 GBG70074.1 - 0.095 11.7 0.4 0.25 10.4 0.4 1.8 1 1 0 1 1 1 0 Coatomer WD associated region RT_RNaseH_2 PF17919.1 GBG70075.1 - 4.5e-27 94.0 0.0 7.5e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70075.1 - 3.9e-24 85.0 0.0 6.7e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2249 PF10006.9 GBG70075.1 - 0.12 12.3 0.3 2.1 8.2 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) PTPRCAP PF15713.5 GBG70075.1 - 9.3 6.5 15.4 17 5.7 15.4 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated 14-3-3 PF00244.20 GBG70076.1 - 8.2e-107 355.7 5.2 9.4e-107 355.6 5.2 1.0 1 0 0 1 1 1 1 14-3-3 protein Ima1_N PF09779.9 GBG70076.1 - 0.14 13.0 0.2 1.7 9.5 0.0 2.3 2 1 0 2 2 2 0 Ima1 N-terminal domain TPR_19 PF14559.6 GBG70076.1 - 0.19 12.3 1.9 0.34 11.5 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat 14-3-3 PF00244.20 GBG70077.1 - 9e-107 355.6 5.2 1e-106 355.4 5.2 1.0 1 0 0 1 1 1 1 14-3-3 protein Ima1_N PF09779.9 GBG70077.1 - 0.16 12.8 0.1 1.7 9.5 0.0 2.2 2 0 0 2 2 2 0 Ima1 N-terminal domain TPR_19 PF14559.6 GBG70077.1 - 0.19 12.2 1.9 0.35 11.4 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pinin_SDK_memA PF04696.13 GBG70079.1 - 2.8e-27 95.3 15.9 2.8e-27 95.3 15.9 3.7 4 0 0 4 4 4 1 pinin/SDK/memA/ protein conserved region Integrase_H2C2 PF17921.1 GBG70081.1 - 5e-18 65.0 0.4 1.2e-17 63.7 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70081.1 - 6.1e-15 55.4 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70081.1 - 0.0051 17.0 0.2 0.014 15.6 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG70081.1 - 0.033 14.3 1.9 0.099 12.8 1.9 1.9 1 0 0 1 1 1 0 Zinc knuckle Hex_IIIa PF02455.16 GBG70081.1 - 0.18 10.6 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) RT_RNaseH_2 PF17919.1 GBG70082.1 - 2.6e-19 69.1 0.0 5.3e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70082.1 - 3e-19 69.3 0.0 6.9e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GRP PF07172.11 GBG70082.1 - 1.5 9.6 12.5 4.1 8.2 12.5 1.8 1 0 0 1 1 1 0 Glycine rich protein family DUF810 PF05664.11 GBG70083.1 - 7.3e-145 484.2 0.0 1.2e-132 443.9 0.0 2.1 2 0 0 2 2 2 2 Plant family of unknown function (DUF810) Beta_helix PF13229.6 GBG70084.1 - 1.3e-05 25.1 9.8 0.00038 20.3 9.8 2.2 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG70084.1 - 0.00068 20.0 27.8 0.28 11.8 0.7 6.5 7 0 0 7 7 7 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat VacA2 PF03077.14 GBG70084.1 - 0.86 9.5 0.0 0.86 9.5 0.0 3.7 3 2 2 5 5 5 0 Putative vacuolating cytotoxin 2OG-FeII_Oxy_3 PF13640.6 GBG70085.1 - 6.1e-20 71.9 0.0 8.4e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GBG70085.1 - 6.1e-16 58.8 0.1 1e-14 54.8 0.0 2.1 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 GBG70085.1 - 0.013 16.0 13.8 0.04 14.5 9.9 3.0 2 1 0 2 2 2 0 ShK domain-like RVT_1 PF00078.27 GBG70086.1 - 2.1e-33 115.7 0.1 3.9e-33 114.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70086.1 - 2e-19 69.5 0.3 4.1e-19 68.4 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG70086.1 - 9.6e-19 67.6 0.1 2.9e-18 66.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70086.1 - 3e-11 43.2 0.0 1.4e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG70086.1 - 3.4e-05 23.6 0.0 7.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70086.1 - 0.00041 20.9 0.0 0.00089 19.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG70086.1 - 0.001 19.2 0.1 0.0028 17.8 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG70086.1 - 0.038 14.6 0.0 0.13 12.8 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1266 PF06889.11 GBG70087.1 - 0.0019 18.3 0.1 0.0061 16.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1266) Nrap_D6 PF17407.2 GBG70087.1 - 0.022 14.9 0.1 9.9 6.4 0.1 2.4 1 1 0 2 2 2 0 Nrap protein domain 6 RNase_J_C PF17770.1 GBG70087.1 - 0.14 13.3 0.4 0.57 11.3 0.1 2.1 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain NOA36 PF06524.12 GBG70088.1 - 0.0021 17.5 12.3 0.0021 17.5 12.3 2.4 2 0 0 2 2 2 2 NOA36 protein PPP4R2 PF09184.11 GBG70088.1 - 0.093 12.3 25.9 0.052 13.1 5.1 2.2 2 0 0 2 2 2 0 PPP4R2 Myb_DNA-bind_4 PF13837.6 GBG70089.1 - 0.00033 21.0 0.4 0.0007 19.9 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG70089.1 - 0.1 12.7 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain NST1 PF13945.6 GBG70090.1 - 7 6.7 21.3 11 6.1 21.3 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Glyco_transf_29 PF00777.18 GBG70091.1 - 1.6e-12 47.4 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) ubiquitin PF00240.23 GBG70092.1 - 2.5e-18 65.6 0.1 2e-09 37.0 0.0 3.6 4 0 0 4 4 4 3 Ubiquitin family Rad60-SLD PF11976.8 GBG70092.1 - 1.1e-05 25.2 0.0 0.0031 17.3 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like RAG1 PF12940.7 GBG70092.1 - 0.11 10.5 0.1 0.15 10.1 0.1 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase ubiquitin PF00240.23 GBG70093.1 - 2.4e-18 65.6 0.2 3.7e-09 36.2 0.0 4.3 4 0 0 4 4 4 2 Ubiquitin family Rad60-SLD PF11976.8 GBG70093.1 - 5e-05 23.1 0.0 0.0057 16.5 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like RAG1 PF12940.7 GBG70093.1 - 0.21 9.7 0.1 0.3 9.1 0.1 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase Integrase_H2C2 PF17921.1 GBG70094.1 - 2.9e-13 49.7 0.2 7.7e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70094.1 - 1.9e-12 47.4 0.0 5.9e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG70094.1 - 3.8e-07 30.6 0.0 1.1e-06 29.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70094.1 - 2.1e-06 28.2 0.0 6.9e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG70094.1 - 0.0052 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG70094.1 - 0.014 15.2 0.2 0.032 14.0 0.2 1.5 1 0 0 1 1 1 0 Aspartyl protease Rota_NS53 PF00981.17 GBG70094.1 - 0.034 13.0 2.5 0.061 12.2 2.5 1.3 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) DUF1664 PF07889.12 GBG70094.1 - 0.04 13.9 5.0 0.15 12.1 5.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RVP PF00077.20 GBG70094.1 - 0.18 12.1 0.0 0.5 10.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Proteasome PF00227.26 GBG70095.1 - 1.7e-48 164.6 0.1 2.2e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GBG70095.1 - 6.2e-14 51.4 0.1 1.1e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Sec7 PF01369.20 GBG70096.1 - 2.7e-63 213.0 0.0 6.4e-63 211.8 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GBG70096.1 - 4.3e-36 124.2 1.9 4.3e-36 124.2 1.9 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 GBG70096.1 - 2.2e-33 115.4 9.1 3.1e-31 108.4 0.8 4.9 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 GBG70096.1 - 3e-29 100.7 0.3 8e-26 89.7 0.1 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Mon2_C PF16206.5 GBG70096.1 - 1.4e-06 26.8 0.0 2.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of Mon2 protein MIF4G PF02854.19 GBG70097.1 - 2e-60 204.0 4.7 3.4e-60 203.3 4.7 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 GBG70097.1 - 4.8e-17 62.0 0.2 1.5e-16 60.4 0.0 1.9 2 0 0 2 2 2 1 MA3 domain W2 PF02020.18 GBG70097.1 - 0.00025 21.1 0.0 0.00061 19.9 0.0 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Integrase_H2C2 PF17921.1 GBG70099.1 - 2.2e-16 59.7 0.1 4e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG70099.1 - 0.00011 22.3 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 H2C2 zinc finger PHD PF00628.29 GBG70103.1 - 6.9e-11 41.9 31.5 0.0001 22.1 7.3 4.9 3 1 1 4 4 4 4 PHD-finger C1_1 PF00130.22 GBG70103.1 - 0.011 15.6 3.4 0.011 15.6 3.4 4.7 4 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Terminase_GpA PF05876.12 GBG70103.1 - 0.92 8.0 7.4 1.5 7.3 7.4 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) WD40 PF00400.32 GBG70104.1 - 6.8e-34 115.3 11.8 1.2e-06 29.1 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG70104.1 - 1.5e-17 63.6 0.0 5e-06 26.7 0.0 4.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 GBG70104.1 - 3.6e-17 61.7 0.6 8.9e-17 60.4 0.6 1.7 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 GBG70104.1 - 3.9e-12 45.8 0.3 0.00016 20.7 0.0 3.4 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GBG70104.1 - 1.9e-07 30.1 0.1 0.0042 15.8 0.1 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Hira PF07569.11 GBG70104.1 - 7e-05 22.6 0.1 0.35 10.6 0.0 3.4 2 1 1 3 3 3 2 TUP1-like enhancer of split Nucleoporin_N PF08801.11 GBG70104.1 - 0.00025 19.9 0.1 1 8.1 0.0 4.1 1 1 2 4 4 4 1 Nup133 N terminal like PQQ_2 PF13360.6 GBG70104.1 - 0.025 14.2 0.0 5 6.6 0.0 2.9 1 1 1 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.16 GBG70104.1 - 0.058 11.9 0.0 2 6.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 GBG70104.1 - 0.089 13.3 0.0 14 6.3 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain PD40 PF07676.12 GBG70104.1 - 0.3 11.1 1.5 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat AAA_6 PF12774.7 GBG70105.1 - 9.2e-164 544.1 0.0 1.1e-162 540.5 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 GBG70105.1 - 1.9e-133 445.5 10.4 1.9e-133 445.5 10.4 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 GBG70105.1 - 4.5e-113 377.5 0.9 4.6e-111 370.9 0.0 3.9 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 GBG70105.1 - 2.2e-107 358.2 3.2 3.5e-107 357.6 0.2 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 GBG70105.1 - 1.7e-91 305.3 0.1 1e-88 296.2 0.4 3.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 GBG70105.1 - 7.9e-76 253.6 0.2 3.2e-70 235.3 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 GBG70105.1 - 9.5e-55 184.9 0.0 3.6e-54 183.0 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GBG70105.1 - 6.4e-47 158.5 0.0 1.3e-44 151.1 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 GBG70105.1 - 6.5e-45 153.6 9.6 8.7e-45 153.2 8.0 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 GBG70105.1 - 3.8e-32 111.1 0.1 1.6e-31 109.1 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 GBG70105.1 - 2.5e-19 69.3 0.0 3.4e-18 65.7 0.0 2.9 2 1 1 3 3 2 1 AAA+ lid domain AAA_5 PF07728.14 GBG70105.1 - 8.3e-17 61.5 0.0 1.3e-05 25.2 0.0 5.9 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GBG70105.1 - 2e-07 31.4 0.2 0.53 10.6 0.0 4.5 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 GBG70105.1 - 7.1e-06 26.5 0.2 1.1 9.7 0.1 4.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG70105.1 - 0.00014 22.3 7.5 2 8.8 0.0 6.2 7 0 0 7 7 5 2 AAA ATPase domain RNA_helicase PF00910.22 GBG70105.1 - 0.00023 21.5 0.9 4.4 7.8 0.0 4.1 4 0 0 4 4 3 1 RNA helicase Sigma54_activat PF00158.26 GBG70105.1 - 0.0018 18.0 0.1 5.6 6.6 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain ResIII PF04851.15 GBG70105.1 - 0.0026 17.8 2.5 0.07 13.1 0.0 4.1 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit DUF853 PF05872.12 GBG70105.1 - 0.0034 16.0 1.2 3 6.3 0.0 3.2 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) Mg_chelatase PF01078.21 GBG70105.1 - 0.012 15.0 0.3 0.22 10.9 0.0 3.2 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI T3SSipB PF16535.5 GBG70105.1 - 0.017 15.6 14.2 0.69 10.4 4.1 2.7 2 0 0 2 2 2 0 Type III cell invasion protein SipB AAA_18 PF13238.6 GBG70105.1 - 0.035 14.7 0.0 0.49 10.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GBG70105.1 - 0.044 13.5 0.5 6.3 6.5 0.2 3.1 3 0 0 3 3 3 0 AAA domain Agenet PF05641.12 GBG70105.1 - 0.082 13.4 0.1 1.5 9.4 0.0 2.7 2 0 0 2 2 2 0 Agenet domain FtsK_SpoIIIE PF01580.18 GBG70105.1 - 0.086 12.2 1.1 16 4.8 0.0 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_24 PF13479.6 GBG70105.1 - 0.11 12.1 0.0 5.5 6.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 GBG70105.1 - 0.42 10.2 2.0 14 5.3 0.2 2.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Sec34 PF04136.15 GBG70105.1 - 0.47 10.3 14.3 1.7 8.5 0.1 4.7 6 0 0 6 6 4 0 Sec34-like family RT_RNaseH_2 PF17919.1 GBG70106.1 - 5.4e-32 109.8 0.0 1e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70106.1 - 1.1e-27 96.4 0.1 2.2e-27 95.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70106.1 - 1.1e-25 90.4 0.1 2.2e-25 89.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70106.1 - 3.1e-18 65.6 0.5 2.3e-17 62.8 0.4 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG70106.1 - 7.2e-15 55.2 0.0 2.2e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70106.1 - 0.022 15.0 0.0 0.095 12.9 0.0 2.2 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG70107.1 - 2.1e-31 109.2 0.1 2.9e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG70107.1 - 0.0036 17.1 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease CCDC85 PF10226.9 GBG70109.1 - 0.0076 16.0 0.4 0.0076 16.0 0.4 2.0 2 0 0 2 2 2 1 CCDC85 family DivIC PF04977.15 GBG70109.1 - 0.15 11.8 2.5 0.5 10.2 2.5 1.9 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 GBG70109.1 - 0.77 9.9 9.0 0.055 13.6 3.1 2.2 2 0 0 2 2 2 0 Basic region leucine zipper RT_RNaseH_2 PF17919.1 GBG70110.1 - 1.5e-29 102.0 0.0 2.5e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70110.1 - 6.8e-27 93.8 0.0 1.1e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70110.1 - 5.2e-09 36.0 0.1 8.7e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plant_NMP1 PF06694.11 GBG70111.1 - 2.6e-105 352.1 0.0 3.5e-105 351.6 0.0 1.2 1 0 0 1 1 1 1 Plant nuclear matrix protein 1 (NMP1) Pkinase PF00069.25 GBG70112.1 - 2e-75 253.6 0.0 2.3e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70112.1 - 1.1e-38 133.0 0.8 3.8e-38 131.3 0.8 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG70112.1 - 0.0068 16.4 0.0 0.17 11.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GBG70112.1 - 0.012 15.2 0.8 0.019 14.5 0.8 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 GBG70112.1 - 0.016 14.5 0.4 0.054 12.8 0.4 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GBG70113.1 - 2.1e-75 253.5 0.0 2.5e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70113.1 - 1.2e-38 132.9 0.8 4e-38 131.2 0.8 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG70113.1 - 0.0072 16.3 0.0 0.16 11.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GBG70113.1 - 0.013 15.1 0.8 0.02 14.5 0.8 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 GBG70113.1 - 0.017 14.4 0.4 0.057 12.8 0.4 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_PH PF01138.21 GBG70114.1 - 2.8e-39 134.7 0.0 1.2e-18 67.9 0.0 3.0 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GBG70114.1 - 5.4e-18 64.8 1.1 1.4e-12 47.5 0.2 2.8 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 GBG70114.1 - 9.3e-10 38.7 0.0 2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 GBG70114.1 - 5.4e-08 32.5 2.6 1.5e-07 31.1 2.6 1.8 1 0 0 1 1 1 1 KH domain PNPase PF03726.14 GBG70114.1 - 0.0003 21.2 8.7 0.11 13.1 3.0 2.9 1 1 1 2 2 2 2 Polyribonucleotide nucleotidyltransferase, RNA binding domain RrnaAD PF00398.20 GBG70115.1 - 2.5e-41 141.5 0.0 3.8e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GBG70115.1 - 5.2e-06 27.1 0.0 1.2e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG70115.1 - 0.0025 18.4 0.0 0.0061 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG70115.1 - 0.065 14.0 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF4112 PF13430.6 GBG70115.1 - 0.073 13.4 0.1 0.27 11.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4112) Lipase_3 PF01764.25 GBG70116.1 - 3.3e-22 78.9 0.1 9.4e-22 77.4 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Lipase3_N PF03893.16 GBG70116.1 - 1.3e-06 28.3 0.4 4.3e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 GBG70116.1 - 0.014 14.7 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 GBG70116.1 - 0.022 14.7 0.1 0.049 13.5 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 GBG70116.1 - 0.22 11.0 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DBC1 PF14443.6 GBG70117.1 - 6.4e-44 148.9 0.1 1.3e-43 147.9 0.1 1.5 1 0 0 1 1 1 1 DBC1 Presenilin PF01080.17 GBG70118.1 - 0.51 9.1 3.8 0.58 8.9 3.8 1.0 1 0 0 1 1 1 0 Presenilin EIF4E-T PF10477.9 GBG70118.1 - 0.58 8.9 8.8 0.7 8.6 8.8 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SprA-related PF12118.8 GBG70118.1 - 0.6 9.2 6.0 0.68 9.0 6.0 1.1 1 0 0 1 1 1 0 SprA-related family Nop14 PF04147.12 GBG70118.1 - 2.9 6.0 14.9 3.5 5.7 14.9 1.0 1 0 0 1 1 1 0 Nop14-like family SpoIIP PF07454.11 GBG70118.1 - 4.3 6.7 7.1 5.5 6.4 7.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 GBG70118.1 - 4.9 6.9 11.1 6.1 6.6 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 GBG70118.1 - 8.3 6.1 6.0 11 5.7 6.0 1.1 1 0 0 1 1 1 0 Connexin EF-hand_7 PF13499.6 GBG70119.1 - 0.01 16.3 0.4 0.038 14.5 0.4 2.1 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 GBG70119.1 - 0.057 13.4 0.1 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain CPSF100_C PF13299.6 GBG70119.1 - 0.2 11.9 22.9 1.5 8.9 11.8 2.9 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 GBG70119.1 - 6.6 5.6 15.0 6.4 5.6 7.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) GTP_EFTU PF00009.27 GBG70120.1 - 1.4e-53 181.3 0.0 2e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GBG70120.1 - 5.4e-39 133.0 0.1 1.2e-38 131.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GBG70120.1 - 1.7e-13 50.7 0.2 1.7e-13 50.7 0.2 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG70120.1 - 0.00017 21.6 0.3 0.00078 19.5 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GBG70120.1 - 0.00022 20.7 0.1 0.0042 16.5 0.1 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 GBG70120.1 - 0.038 13.9 2.7 0.062 13.2 0.2 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 GBG70120.1 - 0.12 12.4 0.3 17 5.4 0.2 2.4 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 GBG70120.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Clathrin PF00637.20 GBG70121.1 - 9.6e-197 644.8 27.6 1.3e-31 109.4 0.2 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 GBG70121.1 - 1.8e-31 107.9 1.0 1.1e-30 105.4 0.2 2.6 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 GBG70121.1 - 8.1e-26 89.0 0.0 1.4e-07 31.4 0.0 6.4 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin-link PF09268.10 GBG70121.1 - 1.6e-09 36.9 0.1 4.4e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 GBG70121.1 - 0.0039 16.3 0.4 1.4 7.9 0.1 2.9 2 0 0 2 2 2 2 Coatomer WD associated region ASRT PF07100.11 GBG70121.1 - 0.049 13.7 0.1 0.2 11.7 0.1 2.0 1 0 0 1 1 1 0 Anabaena sensory rhodopsin transducer TPR_1 PF00515.28 GBG70121.1 - 0.051 13.4 2.4 29 4.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG70121.1 - 0.054 14.3 0.4 47 5.2 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG70121.1 - 0.064 13.4 0.4 5.2 7.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG70122.1 - 2.6e-27 95.8 0.1 4e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70122.1 - 3.4e-21 75.1 0.0 1.9e-09 37.5 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70122.1 - 1.2e-20 73.7 0.0 2.7e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70122.1 - 2.4e-15 56.4 0.0 2.4e-15 56.4 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG70122.1 - 6.8e-13 48.8 0.0 2.1e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG70122.1 - 1e-09 38.1 0.0 2.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG70122.1 - 0.00029 21.0 0.0 0.0012 19.1 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG70122.1 - 0.084 13.5 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Thioredoxin PF00085.20 GBG70123.1 - 0.0034 17.4 0.0 0.011 15.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin RVT_1 PF00078.27 GBG70124.1 - 1.5e-19 70.5 0.0 2.4e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG70124.1 - 0.0003 21.0 0.6 0.0014 18.9 0.1 2.5 2 1 0 2 2 2 1 Retrotransposon gag protein FAT PF02259.23 GBG70124.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 FAT domain rve PF00665.26 GBG70125.1 - 2.5e-12 47.0 0.0 8.1e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG70125.1 - 1.2e-09 37.9 0.9 5.9e-09 35.7 0.0 2.5 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain COX5B PF01215.19 GBG70126.1 - 1.6e-17 63.4 0.0 2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 GBG70126.1 - 2e-07 30.9 0.3 3.1e-07 30.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger domain Coronavirus_5 PF05528.11 GBG70126.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Coronavirus gene 5 protein Zn-C2H2_12 PF18112.1 GBG70126.1 - 0.11 13.0 0.5 0.22 12.0 0.5 1.4 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain DUF2423 PF10338.9 GBG70127.1 - 0.0026 18.0 1.9 0.0026 18.0 1.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Med3 PF11593.8 GBG70127.1 - 8.7 5.4 10.3 9.8 5.2 10.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Myc_N PF01056.18 GBG70128.1 - 0.003 17.5 0.5 0.0035 17.3 0.5 1.0 1 0 0 1 1 1 1 Myc amino-terminal region Uso1_p115_C PF04871.13 GBG70128.1 - 0.0047 17.3 3.4 0.0063 16.9 3.4 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region CNDH2_C PF16858.5 GBG70128.1 - 0.048 13.5 1.8 0.051 13.4 1.8 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term NPR3 PF03666.13 GBG70128.1 - 2 7.1 3.7 2 7.1 3.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DEK_C PF08766.11 GBG70129.1 - 2.5e-15 56.1 1.6 4.6e-15 55.3 1.6 1.5 1 0 0 1 1 1 1 DEK C terminal domain RVT_1 PF00078.27 GBG70130.1 - 0.00046 19.8 0.0 0.00073 19.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rad17 PF03215.15 GBG70131.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain CotH PF08757.11 GBG70131.1 - 0.034 13.7 0.1 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 CotH kinase protein gag-asp_proteas PF13975.6 GBG70132.1 - 3.3e-08 34.0 0.1 1.9e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70132.1 - 8.5e-05 23.1 0.1 0.00034 21.2 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG70132.1 - 0.0044 17.3 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG70132.1 - 0.013 15.3 0.1 0.033 14.0 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease VWA_CoxE PF05762.14 GBG70134.1 - 0.036 13.5 2.3 0.052 12.9 2.3 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein HTH_32 PF13565.6 GBG70134.1 - 0.11 13.1 0.2 0.11 13.1 0.2 2.2 2 0 0 2 2 2 0 Homeodomain-like domain RVT_1 PF00078.27 GBG70136.1 - 1.5e-31 109.7 0.7 2e-31 109.2 0.7 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ldl_recept_a PF00057.18 GBG70137.1 - 1.5e-50 169.1 126.8 5.8e-09 36.0 5.3 10.8 8 2 2 10 10 10 10 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 GBG70138.1 - 1.9e-44 149.6 146.9 4.9e-08 33.1 8.0 11.1 10 1 1 11 11 11 10 Low-density lipoprotein receptor domain class A RVT_1 PF00078.27 GBG70138.1 - 2e-09 37.3 0.1 3.5e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG70138.1 - 2.4e-06 28.1 0.0 5.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70138.1 - 4.9e-06 27.0 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG70138.1 - 1e-05 25.3 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG70138.1 - 1.8e-05 24.5 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG70138.1 - 0.00031 20.6 0.0 0.00092 19.1 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG70138.1 - 0.016 15.5 1.5 0.031 14.5 0.1 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein DUF4407 PF14362.6 GBG70138.1 - 0.051 12.9 4.8 0.1 11.9 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ldl_recept_a PF00057.18 GBG70139.1 - 1.3e-30 105.2 75.1 3.3e-07 30.4 3.3 6.5 5 1 0 6 6 6 6 Low-density lipoprotein receptor domain class A DUF659 PF04937.15 GBG70140.1 - 2.2e-28 99.0 0.3 3.6e-28 98.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG70140.1 - 5.8e-05 22.8 0.1 0.00017 21.3 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TFIIA_gamma_N PF02268.16 GBG70140.1 - 0.032 14.3 0.1 11 6.1 0.0 2.9 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain AphA_like PF14557.6 GBG70140.1 - 0.089 12.5 0.8 5.3 6.7 0.1 2.5 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator WH1 PF00568.23 GBG70141.1 - 0.054 13.4 0.0 0.38 10.7 0.0 2.2 3 0 0 3 3 3 0 WH1 domain E1-E2_ATPase PF00122.20 GBG70142.1 - 2.8e-43 147.6 3.6 2.8e-43 147.6 3.6 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GBG70142.1 - 3.8e-17 63.3 0.2 2.8e-16 60.4 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GBG70142.1 - 7.4e-13 48.0 0.0 2.3e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GBG70142.1 - 0.00024 21.0 0.1 0.0063 16.3 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GBG70142.1 - 0.0009 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) MIF4G_like_2 PF09090.11 GBG70142.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 MIF4G like Ion_trans_2 PF07885.16 GBG70142.1 - 6.4 6.8 10.0 0.6 10.1 0.1 3.4 3 0 0 3 3 3 0 Ion channel zf-CCHC PF00098.23 GBG70144.1 - 1e-12 47.5 13.4 8.6e-07 28.8 2.0 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 GBG70144.1 - 5.3e-07 29.3 9.0 0.0011 18.8 2.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 GBG70144.1 - 0.019 14.9 7.3 0.31 11.0 0.4 2.8 3 0 0 3 3 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG70144.1 - 0.028 14.2 3.6 0.74 9.7 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG70144.1 - 0.039 13.6 6.5 0.26 11.1 0.5 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DDHD PF02862.17 GBG70144.1 - 0.25 11.4 10.6 0.044 13.9 5.0 2.0 2 0 0 2 2 2 0 DDHD domain SAPS PF04499.15 GBG70144.1 - 0.45 9.2 7.2 0.42 9.3 6.1 1.6 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein zf-CCHC_4 PF14392.6 GBG70144.1 - 0.64 9.8 7.7 5.1 6.9 0.6 2.8 3 0 0 3 3 3 0 Zinc knuckle DUF5308 PF17233.2 GBG70144.1 - 0.75 10.0 4.8 3.1 8.0 1.4 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5308) KIND PF16474.5 GBG70144.1 - 4.8 7.0 16.3 0.085 12.7 8.1 2.0 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain DUF2229 PF09989.9 GBG70144.1 - 6.7 6.3 9.0 0.32 10.6 0.7 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Scytalone_dh PF02982.14 GBG70145.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Scytalone dehydratase NHL PF01436.21 GBG70148.1 - 0.00084 19.3 0.1 21 5.4 0.0 4.0 3 0 0 3 3 3 3 NHL repeat PQQ_3 PF13570.6 GBG70148.1 - 0.013 16.0 0.5 4.5 7.9 0.0 4.3 4 0 0 4 4 4 0 PQQ-like domain RT_RNaseH_2 PF17919.1 GBG70149.1 - 9.3e-33 112.3 0.0 1.8e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70149.1 - 8e-29 100.0 0.0 1.9e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70149.1 - 5.7e-27 94.7 0.1 9.2e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70149.1 - 3.9e-16 58.9 0.0 8.4e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70149.1 - 4.2e-16 59.2 0.0 1.7e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG70150.1 - 7.6e-27 94.3 0.0 1.4e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70150.1 - 2.5e-21 75.6 0.0 5.7e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70150.1 - 3.8e-20 72.1 0.0 8.1e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70150.1 - 1.8e-06 27.9 0.9 4.4e-06 26.7 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Senescence_reg PF04520.13 GBG70150.1 - 0.12 13.2 2.6 0.2 12.5 1.9 1.7 2 0 0 2 2 2 0 Senescence regulator NHL PF01436.21 GBG70151.1 - 0.00045 20.1 0.6 1.5 9.0 0.0 3.8 3 0 0 3 3 3 1 NHL repeat SGL PF08450.12 GBG70151.1 - 0.0056 16.3 0.0 0.11 12.0 0.0 2.4 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 GBG70151.1 - 0.02 15.4 1.0 5.7 7.6 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Lactonase PF10282.9 GBG70151.1 - 0.052 12.8 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Reg_prop PF07494.11 GBG70151.1 - 0.12 12.7 0.1 2.4 8.7 0.1 3.1 3 0 0 3 3 3 0 Two component regulator propeller Chlam_PMP PF02415.17 GBG70152.1 - 0.059 13.9 21.0 0.56 10.8 0.7 6.5 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RT_RNaseH_2 PF17919.1 GBG70153.1 - 6.7e-38 128.7 0.1 1.9e-29 101.6 0.0 2.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70153.1 - 3.4e-21 75.5 0.0 6.2e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70153.1 - 1.8e-06 27.6 0.1 2.7e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chlam_PMP PF02415.17 GBG70154.1 - 0.5 11.0 13.9 8.1 7.2 0.1 5.9 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat gag-asp_proteas PF13975.6 GBG70156.1 - 0.00015 22.3 0.0 0.00049 20.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70156.1 - 0.0046 17.6 0.4 0.015 15.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG70156.1 - 0.029 14.7 0.0 0.073 13.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2610 PF11020.8 GBG70156.1 - 0.043 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) DUF1048 PF06304.11 GBG70156.1 - 0.051 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) UBA2_C PF16195.5 GBG70156.1 - 0.53 11.0 9.6 0.1 13.3 5.0 2.1 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus NIF PF03031.18 GBG70158.1 - 5.5e-20 71.7 0.0 1.2e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 GBG70158.1 - 0.00022 21.5 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GBG70158.1 - 0.0016 18.3 0.1 0.0031 17.4 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain COG4 PF08318.12 GBG70159.1 - 1.3e-71 241.5 0.0 2.2e-71 240.7 0.0 1.4 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 GBG70159.1 - 5.9e-07 28.7 0.3 9.7e-07 28.0 0.3 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Sec10 PF07393.11 GBG70159.1 - 0.00029 19.4 0.2 0.00059 18.4 0.2 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec10 BUD22 PF09073.10 GBG70159.1 - 0.0047 16.3 7.4 0.007 15.8 7.4 1.2 1 0 0 1 1 1 1 BUD22 DIL PF01843.19 GBG70159.1 - 0.079 13.2 1.9 0.15 12.4 0.1 2.4 3 0 0 3 3 3 0 DIL domain DUF2201_N PF13203.6 GBG70159.1 - 1.4 8.4 6.7 3.2 7.3 6.7 1.6 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4746 PF15928.5 GBG70159.1 - 4.3 6.7 8.7 7.4 5.9 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sucrose_synth PF00862.19 GBG70160.1 - 5.7e-256 850.1 0.0 6.9e-256 849.8 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG70160.1 - 5.2e-27 94.5 0.0 9.7e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG70160.1 - 5e-10 39.9 0.0 1.2e-09 38.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG70160.1 - 0.00038 20.8 0.0 0.0015 18.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG70160.1 - 0.0019 18.2 0.3 0.093 12.7 0.1 2.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Pox_D5 PF03288.16 GBG70160.1 - 0.044 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like RVT_1 PF00078.27 GBG70162.1 - 4.9e-14 52.4 0.0 6.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RR_TM4-6 PF06459.12 GBG70162.1 - 0.66 9.8 7.6 0.99 9.2 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4820 PF16091.5 GBG70162.1 - 0.88 8.9 2.7 1.3 8.3 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CDC45 PF02724.14 GBG70162.1 - 6.4 4.9 14.3 8.6 4.5 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG70162.1 - 9.2 4.3 18.4 12 3.9 18.4 1.1 1 0 0 1 1 1 0 Nop14-like family RRM_1 PF00076.22 GBG70163.1 - 2.8e-15 55.9 0.0 6.4e-08 32.3 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG70163.1 - 0.00029 20.6 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif API5 PF05918.11 GBG70163.1 - 0.0064 15.4 2.7 0.013 14.3 0.0 2.9 3 0 0 3 3 3 1 Apoptosis inhibitory protein 5 (API5) RT_RNaseH_2 PF17919.1 GBG70165.1 - 2.3e-31 107.8 0.0 4.7e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70165.1 - 8.2e-26 90.3 0.0 1.5e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70165.1 - 1.2e-19 70.8 0.0 2.2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG70165.1 - 2.7e-06 27.8 0.0 5.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70165.1 - 0.00012 22.7 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease PCI PF01399.27 GBG70165.1 - 0.0062 17.0 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 PCI domain RVP_2 PF08284.11 GBG70165.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF5095 PF17016.5 GBG70165.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Asp_protease PF09668.10 GBG70165.1 - 0.17 11.7 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG70165.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 GBG70166.1 - 1.3e-14 54.0 1.4 2e-14 53.4 0.4 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG70166.1 - 4.4e-08 33.3 0.0 7.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG70166.1 - 0.00046 20.0 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG70166.1 - 0.09 13.0 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Sina PF03145.16 GBG70168.1 - 2.2e-80 269.3 0.0 2.2e-80 269.3 0.0 2.0 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4_3 PF13920.6 GBG70168.1 - 0.0073 16.1 10.4 0.0073 16.1 10.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG70168.1 - 0.062 13.2 16.2 0.17 11.8 16.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 GBG70168.1 - 0.69 10.7 12.5 2.8 8.7 0.0 3.6 2 1 1 3 3 3 0 TRAF-type zinc finger RVT_1 PF00078.27 GBG70169.1 - 1.9e-30 106.0 0.1 2.7e-30 105.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG70169.1 - 0.033 14.1 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain UQ_con PF00179.26 GBG70170.1 - 2.8e-54 182.6 0.1 3.1e-54 182.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GBG70170.1 - 0.0045 17.3 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 GBG70170.1 - 0.006 16.3 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GBG70170.1 - 0.025 14.5 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 UEV domain BCAS3 PF12490.8 GBG70173.1 - 2.7e-37 128.6 0.0 6.7e-37 127.3 0.0 1.7 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 GBG70173.1 - 0.012 16.5 3.6 0.79 10.7 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Serglycin PF04360.12 GBG70173.1 - 0.026 14.4 0.4 0.097 12.6 0.4 1.9 1 0 0 1 1 1 0 Serglycin UQ_con PF00179.26 GBG70174.1 - 1.6e-18 66.7 0.5 1.7e-18 66.7 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GBG70174.1 - 0.1 12.9 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 RWD domain Prok-E2_E PF14462.6 GBG70174.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Prokaryotic E2 family E UQ_con PF00179.26 GBG70175.1 - 4e-05 23.3 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TFIIS_C PF01096.18 GBG70176.1 - 0.009 15.8 2.4 0.009 15.8 2.4 3.6 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) TFIIA PF03153.13 GBG70176.1 - 0.19 11.7 28.2 0.28 11.2 28.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn_Tnp_IS1595 PF12760.7 GBG70176.1 - 2.1 8.4 6.4 3.2 7.8 0.1 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain SOBP PF15279.6 GBG70176.1 - 3.9 8.0 27.2 6.2 7.3 27.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein LBP_BPI_CETP_C PF02886.17 GBG70177.1 - 3e-30 105.4 0.0 1.4e-16 60.7 0.0 2.1 2 0 0 2 2 2 2 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 GBG70177.1 - 9.1e-17 61.1 0.0 1.7e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain RVT_1 PF00078.27 GBG70178.1 - 9.3e-20 71.1 0.1 1.7e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70178.1 - 1.1e-16 60.6 0.5 3.8e-16 58.9 0.5 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG70178.1 - 2.8e-14 53.0 0.0 6.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70178.1 - 8.1e-12 45.4 0.1 1.2e-05 25.5 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Glutaredoxin PF00462.24 GBG70178.1 - 9.5e-11 41.8 0.1 2.5e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Glutaredoxin rve PF00665.26 GBG70178.1 - 0.00038 20.6 0.0 0.17 12.0 0.0 2.7 1 1 1 2 2 2 2 Integrase core domain SH3BGR PF04908.15 GBG70178.1 - 0.0022 18.1 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein zf-H2C2 PF09337.10 GBG70178.1 - 1.2 9.4 4.7 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 H2C2 zinc finger Baculo_PEP_C PF04513.12 GBG70178.1 - 2.8 8.0 5.5 5.6 7.0 5.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.16 GBG70180.1 - 2.9e-46 158.0 47.7 3.4e-36 124.9 23.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GBG70180.1 - 2.9 6.1 10.2 1 7.6 0.3 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Hyccin PF09790.9 GBG70181.1 - 0.00075 18.7 0.2 0.0012 18.1 0.2 1.2 1 0 0 1 1 1 1 Hyccin RT_RNaseH_2 PF17919.1 GBG70182.1 - 1.5e-30 105.1 0.1 3.6e-30 103.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70182.1 - 1.6e-28 99.1 1.4 2e-28 98.8 0.2 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70182.1 - 4.3e-09 36.2 0.0 6.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70182.1 - 5e-05 23.3 0.1 0.00015 21.8 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG70182.1 - 0.095 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG70183.1 - 1.8e-31 108.1 0.0 3.7e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70183.1 - 5.4e-30 104.5 0.0 8.7e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70183.1 - 2.3e-26 92.1 0.0 4.7e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70184.1 - 1.5e-18 66.6 0.1 2.7e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70184.1 - 6.9e-14 52.1 0.0 1.5e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70184.1 - 0.03 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger DUF1564 PF07600.11 GBG70184.1 - 0.18 11.5 0.3 0.63 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RT_RNaseH PF17917.1 GBG70185.1 - 7e-27 93.8 0.1 2.7e-26 91.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70185.1 - 4.8e-19 68.3 0.0 1.1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3138 PF11336.8 GBG70185.1 - 0.2 10.3 1.1 0.33 9.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Phage_GPO PF05929.11 GBG70185.1 - 0.35 10.4 0.0 0.35 10.4 0.0 3.0 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3629 PF12302.8 GBG70185.1 - 1.1 8.7 8.1 2.4 7.5 8.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DUF2950 PF11453.8 GBG70185.1 - 1.4 8.0 10.3 2.1 7.4 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) TTKRSYEDQ PF10212.9 GBG70185.1 - 8.6 5.2 14.8 12 4.8 14.8 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Pkinase PF00069.25 GBG70186.1 - 8.8e-25 87.5 0.0 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70186.1 - 7e-14 51.7 0.0 8.8e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG70186.1 - 1.3e-10 40.7 0.0 1.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG70186.1 - 0.00024 21.1 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GBG70186.1 - 0.042 12.8 0.1 0.06 12.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TP1 PF02079.16 GBG70186.1 - 0.09 12.7 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Nuclear transition protein 1 K_channel_TID PF07941.11 GBG70186.1 - 0.49 10.9 13.5 1.2 9.6 13.5 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain zf-CCHC PF00098.23 GBG70187.1 - 0.033 14.3 2.2 0.053 13.6 2.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Asp PF00026.23 GBG70189.1 - 7.3e-115 383.7 0.0 9.3e-115 383.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SapB_2 PF03489.17 GBG70189.1 - 1.8e-13 50.3 0.9 3.7e-13 49.3 0.9 1.5 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.15 GBG70189.1 - 1.4e-12 47.3 0.2 3.3e-12 46.2 0.2 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 1 TAXi_N PF14543.6 GBG70189.1 - 3.2e-11 43.8 0.0 1.6e-07 31.8 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GBG70189.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal TIM21 PF08294.11 GBG70190.1 - 1.3e-24 86.7 0.0 2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 TIM21 Chromo PF00385.24 GBG70190.1 - 0.0014 18.5 0.2 0.003 17.4 0.0 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Coa1 PF08695.10 GBG70190.1 - 0.003 17.3 0.0 0.015 15.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 RVT_1 PF00078.27 GBG70191.1 - 4.5e-30 104.8 0.1 2.3e-29 102.5 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70191.1 - 1.3e-26 92.6 0.0 3.9e-26 91.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70191.1 - 1.4e-23 83.2 0.0 3.8e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG70191.1 - 0.0038 17.5 1.2 0.038 14.3 0.0 3.3 2 0 0 2 2 2 1 Retrotransposon gag protein Myosin_tail_1 PF01576.19 GBG70191.1 - 0.039 11.8 0.3 0.059 11.2 0.3 1.2 1 0 0 1 1 1 0 Myosin tail NPV_P10 PF05531.12 GBG70191.1 - 0.22 12.0 2.0 0.55 10.7 0.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HIP1_clath_bdg PF16515.5 GBG70191.1 - 1 10.0 8.6 0.074 13.7 1.2 2.7 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Usp PF00582.26 GBG70192.1 - 3.2 8.2 7.2 4.4 7.8 6.9 1.4 2 0 0 2 2 2 0 Universal stress protein family Ribosomal_L27A PF00828.19 GBG70193.1 - 6.9e-28 97.9 0.0 1.2e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RRF PF01765.19 GBG70194.1 - 2.3e-45 154.5 0.0 2.3e-45 154.5 0.0 1.6 2 0 0 2 2 2 1 Ribosome recycling factor Integrase_H2C2 PF17921.1 GBG70196.1 - 5.1e-18 64.9 0.1 9.9e-18 64.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG70196.1 - 9e-10 38.4 0.0 2.6e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70196.1 - 1.1e-07 32.4 0.0 3.3e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70196.1 - 1.9e-06 28.3 0.0 6.9e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG70196.1 - 0.00028 20.7 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG70196.1 - 0.00035 20.8 0.1 0.0053 17.0 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG70196.1 - 0.00043 20.5 0.0 0.0015 18.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70196.1 - 0.018 15.3 0.0 0.058 13.6 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger TolA_bind_tri PF16331.5 GBG70196.1 - 0.11 12.6 3.8 0.12 12.5 0.8 2.6 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF16 PF01519.16 GBG70196.1 - 0.4 11.2 7.6 1.6 9.3 4.8 3.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF2040 PF09745.9 GBG70197.1 - 6.6e-35 119.8 19.7 6.6e-35 119.8 19.7 4.4 3 2 2 5 5 5 1 Coiled-coil domain-containing protein 55 (DUF2040) IR1-M PF12185.8 GBG70197.1 - 0.064 13.2 0.2 0.2 11.6 0.2 1.9 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain Integrase_H2C2 PF17921.1 GBG70198.1 - 1.2e-15 57.3 0.1 2.7e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70198.1 - 6.8e-07 29.5 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG70198.1 - 0.00051 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70198.1 - 0.00091 19.8 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG70198.1 - 0.0026 17.9 0.0 0.0068 16.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_5 PF14787.6 GBG70198.1 - 0.043 13.5 0.3 0.12 12.1 0.3 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SWIM PF04434.17 GBG70199.1 - 0.025 14.2 1.7 0.056 13.1 1.7 1.5 1 0 0 1 1 1 0 SWIM zinc finger Phyto_Pns9_10 PF05878.11 GBG70200.1 - 0.06 12.5 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF4132 PF13569.6 GBG70200.1 - 0.95 9.2 7.8 0.26 11.1 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4132) Casc1_N PF15927.5 GBG70200.1 - 3.7 7.2 18.1 6.1 6.5 18.1 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus MDM10 PF12519.8 GBG70200.1 - 6.3 5.5 6.7 7.7 5.3 6.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Hid1 PF12722.7 GBG70200.1 - 6.4 4.8 6.3 6.7 4.7 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 GBG70202.1 - 0.34 9.2 11.0 0.57 8.4 11.0 1.3 1 0 0 1 1 1 0 CDC45-like protein ZF-HD_dimer PF04770.12 GBG70203.1 - 2.1e-24 85.6 3.5 5.7e-24 84.2 3.5 1.8 1 0 0 1 1 1 1 ZF-HD protein dimerisation region MAJIN PF15077.6 GBG70203.1 - 1.1 9.0 8.5 1.9 8.2 8.5 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein SDA1 PF05285.12 GBG70203.1 - 5.8 6.2 21.9 9.7 5.5 21.9 1.2 1 0 0 1 1 1 0 SDA1 DUF4820 PF16091.5 GBG70203.1 - 7.2 5.9 8.4 15 4.8 8.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Nop14 PF04147.12 GBG70203.1 - 9.2 4.3 21.9 13 3.9 21.9 1.1 1 0 0 1 1 1 0 Nop14-like family Chorismate_bind PF00425.18 GBG70205.1 - 1.5e-88 296.7 0.0 2.2e-88 296.2 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 GBG70205.1 - 4.8e-26 91.7 0.0 1.5e-25 90.0 0.0 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region COX14 PF14880.6 GBG70205.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF659 PF04937.15 GBG70207.1 - 1.1e-10 41.6 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CDC45 PF02724.14 GBG70207.1 - 0.089 11.1 8.5 0.15 10.4 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein ABC_ATPase PF09818.9 GBG70209.1 - 3.1e-178 593.2 0.0 4.4e-178 592.7 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 GBG70209.1 - 0.0012 19.4 0.0 0.0012 19.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GBG70209.1 - 0.045 13.5 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Retrotrans_gag PF03732.17 GBG70210.1 - 0.0018 18.5 0.2 0.024 14.9 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Baculo_PEP_C PF04513.12 GBG70210.1 - 0.006 16.6 6.3 0.0092 16.0 6.3 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 GBG70210.1 - 0.01 15.9 1.0 0.096 12.8 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TolA_bind_tri PF16331.5 GBG70210.1 - 0.02 14.9 6.4 0.02 14.9 6.4 2.9 2 1 1 3 3 3 0 TolA binding protein trimerisation Spc29 PF17082.5 GBG70210.1 - 0.024 14.5 1.4 0.074 12.9 1.5 1.6 1 1 0 1 1 1 0 Spindle Pole Component 29 DUF1664 PF07889.12 GBG70210.1 - 0.11 12.5 2.3 0.24 11.4 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 GBG70210.1 - 0.14 12.5 1.2 0.28 11.5 1.2 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 GBG70210.1 - 0.35 11.3 2.4 2 8.9 0.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 GBG70210.1 - 1.6 9.0 4.9 0.22 11.8 0.4 1.9 2 0 0 2 2 2 0 Haemolysin XhlA TMPIT PF07851.13 GBG70210.1 - 2.3 7.4 6.5 0.31 10.3 1.2 1.8 2 0 0 2 2 2 0 TMPIT-like protein DUF4763 PF15960.5 GBG70210.1 - 4.8 6.4 12.9 7.3 5.8 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) ATG16 PF08614.11 GBG70210.1 - 8.6 6.5 18.4 21 5.3 18.4 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMP-TENI PF02581.17 GBG70213.1 - 2.7e-47 160.4 0.8 3.2e-47 160.2 0.8 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase QRPTase_C PF01729.19 GBG70213.1 - 0.038 13.8 0.0 0.091 12.5 0.0 1.6 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 GBG70213.1 - 0.046 13.2 0.1 0.12 11.8 0.1 1.6 1 1 1 2 2 2 0 Histidine biosynthesis protein Dus PF01207.17 GBG70213.1 - 0.19 10.8 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) RVT_1 PF00078.27 GBG70214.1 - 4e-28 98.5 0.0 7e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70214.1 - 8e-26 90.0 0.0 1.9e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70214.1 - 5.2e-22 78.1 0.0 1.2e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG70214.1 - 0.00072 20.2 0.0 0.0037 17.9 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70214.1 - 0.028 15.0 0.0 0.073 13.6 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF3006 PF11213.8 GBG70214.1 - 0.4 10.9 2.0 1.1 9.5 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Retrotrans_gag PF03732.17 GBG70214.1 - 0.42 10.9 9.6 1.5 9.2 0.0 4.6 5 0 0 5 5 5 0 Retrotransposon gag protein Phos_pyr_kin PF08543.12 GBG70215.1 - 5.1e-83 278.2 1.8 1.2e-42 146.0 0.0 2.3 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase PfkB PF00294.24 GBG70215.1 - 6.6e-09 35.5 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HAD PF12710.7 GBG70215.1 - 4.1e-05 24.1 0.0 0.0017 18.8 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TMP-TENI PF02581.17 GBG70215.1 - 0.0013 18.1 0.0 0.0028 17.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase Hydrolase PF00702.26 GBG70215.1 - 0.043 14.1 0.1 0.13 12.5 0.1 1.9 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase BORCS7 PF16088.5 GBG70216.1 - 1.1e-06 28.8 0.1 1.3e-06 28.6 0.1 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 Glyco_transf_8 PF01501.20 GBG70217.1 - 8e-36 123.9 0.0 2e-35 122.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GBG70217.1 - 0.00011 21.7 0.1 0.00019 20.9 0.1 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 FAD_binding_7 PF03441.14 GBG70219.1 - 3.6e-65 219.2 0.3 1.3e-64 217.4 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GBG70219.1 - 8e-40 136.5 0.0 2e-39 135.3 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 GBG70220.1 - 3.9e-65 219.1 0.3 1.4e-64 217.3 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GBG70220.1 - 8.4e-40 136.5 0.0 2e-39 135.2 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase Molybdopterin PF00384.22 GBG70223.1 - 2.8e-66 224.3 0.0 2.9e-65 220.9 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 GBG70223.1 - 2.7e-20 72.2 0.3 6.2e-20 71.0 0.3 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 GBG70223.1 - 5e-17 62.3 0.5 1.5e-16 60.8 0.0 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 GBG70223.1 - 4e-16 58.3 0.2 4e-16 58.3 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 GBG70223.1 - 2.1e-08 34.0 0.7 2.1e-08 34.0 0.7 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 GBG70223.1 - 0.3 11.0 1.7 6.2 6.8 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain FAP PF07174.11 GBG70223.1 - 1.8 8.0 11.8 3.3 7.1 11.8 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF659 PF04937.15 GBG70224.1 - 6.3e-29 100.8 0.3 9.3e-29 100.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG70225.1 - 6.9e-23 80.9 0.1 2.1e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70225.1 - 1.1e-21 76.7 0.0 2.4e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70225.1 - 2.5e-13 49.9 0.4 9.4e-13 48.1 0.4 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG70225.1 - 9e-12 45.2 0.0 4.1e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DUF1835 PF08874.10 GBG70225.1 - 0.57 10.4 2.5 10 6.3 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1835) PI3_PI4_kinase PF00454.27 GBG70226.1 - 1.3e-49 169.3 0.0 2.4e-49 168.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 GBG70226.1 - 2.7e-48 165.0 0.0 5.5e-48 163.9 0.0 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.13 GBG70226.1 - 4e-18 65.2 0.5 4.2e-17 61.9 0.0 2.9 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 GBG70226.1 - 2.1e-13 49.8 0.2 5.4e-13 48.5 0.2 1.8 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 GBG70226.1 - 9.2e-05 22.9 2.2 0.13 12.8 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG70226.1 - 0.0035 17.3 0.0 0.0035 17.3 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG70226.1 - 0.0038 17.0 0.0 0.018 14.8 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG70226.1 - 0.023 14.3 0.0 0.27 11.0 0.0 2.8 4 0 0 4 4 4 0 TPR repeat TPR_12 PF13424.6 GBG70226.1 - 0.046 14.0 0.8 16 5.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SPW PF03779.14 GBG70226.1 - 0.047 13.3 0.1 0.21 11.2 0.1 2.2 1 0 0 1 1 1 0 SPW repeat TPR_7 PF13176.6 GBG70226.1 - 0.1 12.7 9.0 0.42 10.8 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG70226.1 - 1.9 9.5 17.0 5.1 8.2 0.6 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat RVP_2 PF08284.11 GBG70227.1 - 9.2e-07 28.7 0.0 1.9e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70227.1 - 2e-06 28.4 0.0 5.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70227.1 - 0.00026 21.5 0.1 0.0014 19.1 0.0 2.3 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG70227.1 - 0.0022 17.8 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG70227.1 - 0.021 14.6 0.0 0.056 13.2 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease Herpes_UL25 PF01499.16 GBG70227.1 - 7.6 4.9 8.6 14 4.1 8.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family SAPS PF04499.15 GBG70229.1 - 2.7 6.7 21.1 3.1 6.5 21.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop53 PF07767.11 GBG70230.1 - 0.00019 21.0 8.7 0.00019 21.0 8.7 2.2 3 0 0 3 3 3 1 Nop53 (60S ribosomal biogenesis) Myc_N PF01056.18 GBG70230.1 - 0.021 14.7 1.1 0.021 14.7 1.1 1.8 2 0 0 2 2 2 0 Myc amino-terminal region Spt5_N PF11942.8 GBG70230.1 - 0.03 15.3 11.9 0.03 15.3 11.9 3.8 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal Rrn6 PF10214.9 GBG70230.1 - 0.27 9.7 1.7 0.47 8.9 1.7 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor U3_snoRNA_assoc PF08297.11 GBG70230.1 - 4.2 8.2 12.4 0.091 13.5 4.6 2.2 2 0 0 2 2 2 0 U3 snoRNA associated RT_RNaseH_2 PF17919.1 GBG70231.1 - 2e-24 85.5 0.0 3.5e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70231.1 - 7.3e-22 77.6 0.0 1.5e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG70231.1 - 0.092 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG70231.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Aminotran_5 PF00266.19 GBG70232.1 - 1.3e-19 70.4 0.0 2.6e-15 56.3 0.0 2.9 3 0 0 3 3 3 2 Aminotransferase class-V MOSC_N PF03476.16 GBG70233.1 - 7.9e-24 83.8 0.0 2.3e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 GBG70233.1 - 5e-19 68.5 0.0 5.7e-15 55.1 0.0 3.0 3 0 0 3 3 3 2 Aminotransferase class-V MOSC PF03473.17 GBG70233.1 - 7.6e-13 48.6 0.9 5.9e-12 45.7 0.9 2.5 1 1 0 1 1 1 1 MOSC domain CMAS PF02353.20 GBG70236.1 - 1.9e-46 158.6 0.9 2.5e-46 158.2 0.9 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 GBG70236.1 - 1e-17 64.3 0.0 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG70236.1 - 1.1e-16 61.2 0.0 2.1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG70236.1 - 2.4e-16 60.2 0.0 4.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG70236.1 - 9.2e-13 48.4 0.0 1.6e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG70236.1 - 1.4e-12 48.2 0.0 2.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG70236.1 - 7.7e-11 41.8 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 GBG70236.1 - 2.5e-07 30.3 0.0 4.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB GidB PF02527.15 GBG70236.1 - 7.2e-06 25.4 0.0 1.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 GBG70236.1 - 1.8e-05 24.3 0.0 5.3e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 GBG70236.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 GBG70236.1 - 0.00032 20.9 0.0 0.001 19.2 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 GBG70236.1 - 0.00038 20.3 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein NodS PF05401.11 GBG70236.1 - 0.00071 19.3 0.0 0.0016 18.1 0.0 1.5 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltr_RsmB-F PF01189.17 GBG70236.1 - 0.0021 17.7 0.0 0.0053 16.4 0.0 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F DUF938 PF06080.12 GBG70236.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 GBG70236.1 - 0.019 14.2 0.0 0.043 13.1 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase domain tRNA_U5-meth_tr PF05958.11 GBG70236.1 - 0.024 13.6 0.1 0.038 13.0 0.1 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF1154 PF06631.11 GBG70236.1 - 0.026 14.5 0.1 0.055 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) PCMT PF01135.19 GBG70236.1 - 0.059 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 GBG70236.1 - 0.076 11.9 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 GBG70236.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 GBG70236.1 - 0.078 14.0 0.0 0.19 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 GBG70236.1 - 0.096 12.2 0.0 0.34 10.4 0.0 1.8 1 1 1 2 2 2 0 Histone methylation protein DOT1 RrnaAD PF00398.20 GBG70236.1 - 0.13 11.3 0.0 0.29 10.2 0.0 1.5 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase VIGSSK PF14773.6 GBG70237.1 - 0.0026 17.8 0.1 0.0026 17.8 0.1 2.8 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal TruB_C_2 PF16198.5 GBG70237.1 - 0.037 14.2 0.0 15 5.8 0.0 3.3 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain MADF_DNA_bdg PF10545.9 GBG70237.1 - 0.67 10.3 13.0 0.2 12.0 0.5 3.6 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like NNMT_PNMT_TEMT PF01234.17 GBG70238.1 - 0.038 13.2 1.3 0.065 12.4 0.6 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Peptidase_C14 PF00656.22 GBG70239.1 - 7.3e-28 98.2 0.0 1.4e-27 97.2 0.0 1.5 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 GBG70240.1 - 5.3e-28 98.6 0.0 9.9e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Caspase domain RT_RNaseH PF17917.1 GBG70241.1 - 8.6e-19 67.8 0.0 2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70241.1 - 2.9e-11 43.3 0.0 7.2e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG70241.1 - 0.00036 20.5 0.3 0.00083 19.3 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG70241.1 - 0.0061 17.1 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease BUD22 PF09073.10 GBG70241.1 - 0.062 12.6 21.4 0.36 10.1 15.3 2.2 2 0 0 2 2 2 0 BUD22 DUF4770 PF15994.5 GBG70241.1 - 0.11 12.7 0.2 0.41 10.9 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) RVT_1 PF00078.27 GBG70242.1 - 1.1e-25 90.4 0.1 1.9e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70242.1 - 4.8e-25 87.5 0.0 1.4e-24 86.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70242.1 - 4.7e-24 84.7 0.0 1.2e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG70242.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG70243.1 - 3.8e-45 154.1 0.2 1.2e-34 119.8 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70243.1 - 1.1e-29 102.8 0.1 2.6e-29 101.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70243.1 - 3.1e-29 100.9 0.0 8.7e-29 99.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG70243.1 - 8.1e-07 28.9 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70243.1 - 8.7e-06 26.3 0.0 1.9e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70243.1 - 0.00065 20.2 0.0 0.0018 18.8 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG70243.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG70243.1 - 0.071 12.9 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease SpoOE-like PF09388.10 GBG70243.1 - 0.21 11.5 3.4 2.7 8.0 0.4 2.9 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein KMP11 PF03037.16 GBG70243.1 - 0.91 10.4 8.3 30 5.5 2.4 4.0 4 0 0 4 4 4 0 Kinetoplastid membrane protein 11 PA26 PF04636.13 GBG70243.1 - 3.4 6.5 7.1 5.6 5.8 7.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Herpes_UL25 PF01499.16 GBG70243.1 - 8.8 4.7 5.8 13 4.2 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Peptidase_C14 PF00656.22 GBG70244.1 - 4.3e-30 105.5 0.0 8e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Ribosomal_L27e PF01777.18 GBG70246.1 - 8.5e-30 103.0 9.0 8.5e-30 103.0 9.0 1.4 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 GBG70246.1 - 0.0035 17.2 0.2 0.0098 15.8 0.2 1.8 1 0 0 1 1 1 1 KOW motif Peptidase_C14 PF00656.22 GBG70247.1 - 6.5e-28 98.3 0.0 1.1e-27 97.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Nif11 PF07862.11 GBG70247.1 - 0.033 14.5 1.3 10 6.5 0.0 4.0 5 0 0 5 5 5 0 Nif11 domain COX4 PF02936.14 GBG70247.1 - 0.052 13.6 0.0 43 4.1 0.0 3.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Peptidase_C14 PF00656.22 GBG70248.1 - 1.2e-27 97.4 0.0 2.2e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Caspase domain COX4 PF02936.14 GBG70248.1 - 0.13 12.3 0.0 42 4.1 0.0 3.3 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV SDA1 PF05285.12 GBG70249.1 - 7.4e-05 22.3 18.0 0.00012 21.7 18.0 1.3 1 0 0 1 1 1 1 SDA1 SAPS PF04499.15 GBG70249.1 - 0.0059 15.4 1.6 0.0059 15.5 1.6 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Presenilin PF01080.17 GBG70249.1 - 0.21 10.3 9.7 0.32 9.7 9.7 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG70249.1 - 0.24 9.6 18.9 0.084 11.1 15.9 1.6 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 GBG70249.1 - 0.44 8.7 27.4 0.73 8.0 27.4 1.3 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 GBG70249.1 - 1.1 7.3 6.7 1.9 6.5 6.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 GBG70249.1 - 5 6.2 7.4 7.3 5.7 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Na_trans_assoc PF06512.13 GBG70249.1 - 5.8 7.1 17.9 14 5.9 17.9 1.7 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2151 PF10221.9 GBG70249.1 - 8.7 4.8 7.8 12 4.3 7.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator N6_N4_Mtase PF01555.18 GBG70251.1 - 4e-06 26.7 0.0 7e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 DNA methylase DUF2213 PF09979.9 GBG70251.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) F5_F8_type_C PF00754.25 GBG70252.1 - 5.5e-09 36.2 0.0 6.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain TfoX_C PF04994.13 GBG70252.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 TfoX C-terminal domain Glyco_hydro_85 PF03644.13 GBG70253.1 - 4.1e-91 305.6 0.7 6.4e-91 304.9 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 CAP_N PF01213.19 GBG70253.1 - 0.25 10.8 1.2 0.54 9.7 1.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RT_RNaseH PF17917.1 GBG70254.1 - 3.4e-30 104.4 0.2 6.9e-29 100.2 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70254.1 - 3.4e-29 100.8 0.0 1.8e-28 98.5 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG70254.1 - 0.066 12.8 14.5 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG70254.1 - 0.098 12.2 0.2 0.19 11.2 0.2 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_UL17 PF04559.12 GBG70254.1 - 1.2 7.8 3.9 1.8 7.3 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein DRY_EERY PF09750.9 GBG70254.1 - 3.6 7.8 8.5 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Alternative splicing regulator PSK PF06404.12 GBG70254.1 - 3.7 8.6 8.6 8.5 7.5 8.6 1.6 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) SNARE_assoc PF09335.11 GBG70255.1 - 7.7e-17 61.9 0.2 1.8e-16 60.7 0.2 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein SNase PF00565.17 GBG70256.1 - 1.5e-25 89.7 0.6 3.4e-25 88.6 0.1 1.9 2 0 0 2 2 2 1 Staphylococcal nuclease homologue Retrotrans_gag PF03732.17 GBG70256.1 - 0.0012 19.1 2.3 0.0027 18.0 0.1 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein DUF1244 PF06844.11 GBG70256.1 - 2.5 8.3 4.3 11 6.2 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1244) CENP-F_leu_zip PF10473.9 GBG70256.1 - 9.5 6.2 7.0 7.6 6.6 0.1 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RT_RNaseH_2 PF17919.1 GBG70257.1 - 9.3e-30 102.6 0.0 2.8e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70257.1 - 1.6e-26 92.6 0.0 3.2e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70257.1 - 7.3e-14 51.6 0.5 2.7e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG70257.1 - 6.3e-13 49.0 0.1 2.8e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG70257.1 - 5.2e-12 45.5 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG70257.1 - 0.00014 22.0 0.0 0.00037 20.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG70260.1 - 1.6e-24 86.7 0.0 2.6e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70260.1 - 2.2e-20 72.6 0.0 1.8e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70260.1 - 2.2e-13 50.1 0.1 9e-13 48.1 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG70260.1 - 3.4e-12 46.6 0.1 1.3e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG70260.1 - 1.8e-10 41.1 0.0 4.3e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG70260.1 - 8e-05 22.8 0.1 0.00016 21.8 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Histone PF00125.24 GBG70262.1 - 8e-23 81.2 3.2 8e-23 81.2 3.2 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Ras PF00071.22 GBG70263.1 - 1.3e-52 177.7 0.0 1.5e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG70263.1 - 3.2e-24 85.5 0.0 6.5e-24 84.5 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG70263.1 - 0.0001 21.8 0.0 0.00021 20.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GBG70263.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SUA5 PF03481.13 GBG70263.1 - 0.076 13.6 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding Gtr1_RagA PF04670.12 GBG70263.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 GBG70263.1 - 0.12 11.9 0.2 0.66 9.5 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region F-box-like PF12937.7 GBG70264.1 - 2.9e-07 30.3 2.3 9e-07 28.7 2.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG70264.1 - 6e-07 29.2 2.4 1.4e-06 28.0 2.4 1.8 1 0 0 1 1 1 1 F-box domain Sad1_UNC PF07738.13 GBG70264.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal F-box_5 PF18511.1 GBG70264.1 - 0.22 11.1 1.4 0.45 10.1 1.4 1.4 1 0 0 1 1 1 0 F-box RT_RNaseH_2 PF17919.1 GBG70265.1 - 4.5e-29 100.4 0.0 3e-28 97.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70265.1 - 6.3e-29 100.3 0.1 6.4e-28 97.1 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70265.1 - 1.1e-17 63.9 1.0 2.1e-17 63.0 1.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70265.1 - 2.3e-15 56.8 0.0 5.2e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG70265.1 - 4.9e-10 39.3 0.0 9.4e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FHA PF00498.26 GBG70265.1 - 6.3e-05 23.3 0.1 0.00015 22.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-H2C2 PF09337.10 GBG70265.1 - 0.0071 16.5 0.2 0.019 15.2 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger FXR_C1 PF16096.5 GBG70265.1 - 0.0083 16.3 4.0 0.017 15.3 0.8 2.7 2 0 0 2 2 2 1 Fragile X-related 1 protein C-terminal region 2 Chromo PF00385.24 GBG70265.1 - 0.27 11.2 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain VWA_2 PF13519.6 GBG70266.1 - 0.00056 20.5 0.0 0.00093 19.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain rve PF00665.26 GBG70267.1 - 1.3e-10 41.5 0.0 2.9e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4200 PF13863.6 GBG70267.1 - 5.5e-05 23.5 10.5 0.00031 21.1 2.8 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) Cast PF10174.9 GBG70267.1 - 0.018 13.3 7.0 0.028 12.7 7.0 1.2 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF4600 PF15372.6 GBG70267.1 - 0.021 15.3 2.8 0.021 15.3 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Phage_GPO PF05929.11 GBG70267.1 - 0.15 11.7 6.7 0.24 11.0 6.7 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase LPP PF04728.13 GBG70267.1 - 0.26 11.7 2.2 1.1 9.8 0.3 2.7 3 0 0 3 3 3 0 Lipoprotein leucine-zipper ZapB PF06005.12 GBG70267.1 - 0.36 11.3 14.8 0.55 10.7 0.2 3.5 2 1 1 3 3 3 0 Cell division protein ZapB DMPK_coil PF08826.10 GBG70267.1 - 1.1 9.5 9.6 0.27 11.4 1.5 3.1 3 0 0 3 3 3 0 DMPK coiled coil domain like Seryl_tRNA_N PF02403.22 GBG70267.1 - 1.1 9.5 9.0 2.1 8.6 2.5 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.21 GBG70267.1 - 2 8.6 12.7 17 5.6 1.2 3.3 2 1 1 3 3 3 0 bZIP transcription factor DUF4200 PF13863.6 GBG70268.1 - 0.00076 19.9 1.4 0.00076 19.9 1.4 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) ERM PF00769.19 GBG70268.1 - 2.9 7.6 35.1 0.74 9.6 21.6 3.1 3 0 0 3 3 3 0 Ezrin/radixin/moesin family RVT_1 PF00078.27 GBG70269.1 - 3.9e-30 105.0 0.0 6.6e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70269.1 - 2.2e-28 98.6 0.7 1.8e-27 95.7 0.1 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70269.1 - 5.8e-27 93.7 0.0 2.6e-26 91.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70269.1 - 2.1e-14 53.4 0.1 4.5e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Ribosomal_S17e PF00833.18 GBG70270.1 - 3.5e-62 207.8 2.2 4.2e-62 207.5 2.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 RCC1 PF00415.18 GBG70271.1 - 5.8e-21 74.9 0.5 3.8e-10 40.2 0.1 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG70271.1 - 4.8e-07 29.4 1.4 0.0021 17.8 0.0 3.3 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GBG70272.1 - 2.1e-39 133.9 3.2 1.6e-11 44.6 0.0 4.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG70272.1 - 2.4e-28 97.3 6.5 6.6e-09 35.3 0.1 3.2 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GBG70273.1 - 7e-60 199.5 16.2 3.5e-13 49.9 0.0 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG70273.1 - 1.6e-47 158.4 27.1 3.1e-10 39.6 0.8 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 GBG70273.1 - 0.14 11.9 0.0 25 4.5 0.0 3.3 3 1 0 3 3 3 0 TUP1-like enhancer of split RCC1 PF00415.18 GBG70274.1 - 7e-35 119.4 10.1 4.5e-12 46.4 0.2 4.9 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RT_RNaseH_2 PF17919.1 GBG70274.1 - 4.8e-32 110.0 0.0 9.8e-32 109.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70274.1 - 1e-29 102.9 0.0 1.8e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70274.1 - 4.3e-18 65.6 0.0 6.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RCC1_2 PF13540.6 GBG70274.1 - 9.8e-17 60.3 16.0 3.4e-07 29.9 3.6 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Peptidase_C7 PF01830.18 GBG70274.1 - 0.092 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase C7 family zinc_ribbon_6 PF14599.6 GBG70275.1 - 2.9e-25 88.0 4.0 2.9e-25 88.0 4.0 3.5 3 1 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 GBG70275.1 - 8.9e-19 67.8 24.2 8.9e-19 67.8 24.2 4.1 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 GBG70275.1 - 3.2e-07 30.6 7.5 3.2e-07 30.6 7.5 5.5 3 2 2 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG70275.1 - 1e-06 28.7 3.8 1e-06 28.7 3.8 3.6 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG70275.1 - 1.7e-06 27.8 5.6 1.7e-06 27.8 5.6 5.0 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) SDA1 PF05285.12 GBG70275.1 - 0.036 13.5 13.3 0.046 13.1 13.3 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG70275.1 - 0.86 9.1 6.6 21 4.5 6.4 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 GBG70275.1 - 2.1 6.6 7.4 2.7 6.2 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG70275.1 - 5.8 5.0 15.1 7.8 4.6 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family FtsJ PF01728.19 GBG70276.1 - 1.6e-54 184.7 0.0 3e-54 183.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 GBG70276.1 - 4.7e-53 180.0 23.1 4.7e-53 180.0 23.1 3.2 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 GBG70276.1 - 8.6e-37 126.5 11.5 8.6e-37 126.5 11.5 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) Nop14 PF04147.12 GBG70277.1 - 0.072 11.3 13.6 0.072 11.3 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 GBG70277.1 - 0.81 8.8 21.3 1 8.5 21.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 GBG70277.1 - 4.3 6.7 21.6 5.3 6.4 21.6 1.1 1 0 0 1 1 1 0 SDA1 H_PPase PF03030.16 GBG70278.1 - 2.3e-252 839.4 31.6 2.9e-252 839.0 31.6 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase zinc_ribbon_16 PF17034.5 GBG70278.1 - 0.24 11.6 0.0 0.46 10.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family FoP_duplication PF13865.6 GBG70279.1 - 0.0069 16.9 9.5 0.012 16.2 9.5 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 zf-CCHC PF00098.23 GBG70280.1 - 5.6e-33 111.5 38.9 1.8e-07 30.9 4.0 5.6 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_5 PF14787.6 GBG70280.1 - 4.3e-11 42.3 30.7 0.0024 17.6 1.3 5.3 5 0 0 5 5 5 4 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 GBG70280.1 - 2.1e-09 37.2 14.4 0.088 12.8 0.1 5.4 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 GBG70280.1 - 4.9e-07 29.4 28.0 0.017 14.8 0.9 5.1 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_6 PF15288.6 GBG70280.1 - 0.0001 22.1 33.0 0.19 11.6 1.4 5.5 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 GBG70280.1 - 0.0047 16.7 34.1 0.0053 16.5 0.7 5.4 5 0 0 5 5 5 3 Zinc knuckle Trypan_PARP PF05887.11 GBG70280.1 - 0.31 11.0 15.6 0.29 11.1 8.2 2.4 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) RSN1_7TM PF02714.15 GBG70281.1 - 3.2e-18 66.0 13.8 6.8e-12 45.3 0.5 2.7 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GBG70281.1 - 1.3e-12 47.7 0.0 3.2e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GBG70281.1 - 1.2e-11 45.1 0.0 2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RVT_1 PF00078.27 GBG70282.1 - 1.8e-29 102.9 0.1 3.2e-29 102.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70282.1 - 2.2e-25 88.6 0.0 1.3e-24 86.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70282.1 - 2.2e-23 82.5 0.0 7.5e-23 80.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70282.1 - 1e-17 64.0 0.5 2.3e-17 62.8 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70282.1 - 2.4e-09 37.4 0.2 1.7e-08 34.6 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG70282.1 - 4.1e-05 24.1 0.0 9.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70282.1 - 0.00017 22.0 0.0 0.00044 20.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG70282.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG70282.1 - 0.0035 17.1 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG70282.1 - 0.0068 16.6 0.0 0.023 14.9 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Arf PF00025.21 GBG70283.1 - 2.7e-37 127.9 0.0 6.2e-37 126.7 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GBG70283.1 - 6.2e-08 32.4 0.0 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 GBG70283.1 - 2.7e-07 30.3 0.0 5.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GBG70283.1 - 1.6e-06 27.6 0.0 6.3e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 GBG70283.1 - 2.5e-05 23.8 0.0 5.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GBG70283.1 - 6.7e-05 22.4 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 GBG70283.1 - 7.5e-05 22.9 0.0 7.5e-05 22.9 0.0 2.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Retrotrans_gag PF03732.17 GBG70283.1 - 0.00094 19.4 0.2 0.0027 17.9 0.2 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein AA_permease_2 PF13520.6 GBG70285.1 - 4.3e-47 160.9 45.7 4.3e-47 160.9 45.7 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 GBG70285.1 - 8.3e-26 90.6 44.8 8.3e-26 90.6 44.8 1.6 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 GBG70285.1 - 2.5e-15 56.3 5.7 2.5e-15 56.3 5.7 4.3 5 0 0 5 5 5 1 C-terminus of AA_permease DUF3883 PF13020.6 GBG70287.1 - 1.9e-16 59.8 0.0 4.1e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 GBG70287.1 - 0.037 13.9 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FRP PF18032.1 GBG70287.1 - 0.15 12.7 0.1 4.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Photoprotection regulator fluorescence recovery protein DUF659 PF04937.15 GBG70288.1 - 7.8e-31 107.0 0.2 1.2e-30 106.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG70288.1 - 0.00069 19.4 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DPBB_1 PF03330.18 GBG70289.1 - 1.5e-14 54.0 0.1 2.8e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG70289.1 - 8.4e-10 38.5 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen Pkinase PF00069.25 GBG70290.1 - 1.3e-47 162.4 0.0 1.8e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70290.1 - 1.5e-46 158.8 0.0 2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 GBG70290.1 - 2.8e-07 30.2 0.1 5e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GBG70290.1 - 0.0022 18.3 0.1 0.0045 17.4 0.1 1.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) APH PF01636.23 GBG70290.1 - 0.0026 17.7 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 GBG70290.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 GBG70290.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase LRR_1 PF00560.33 GBG70290.1 - 0.066 13.8 0.2 15 6.6 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat Rrn6 PF10214.9 GBG70290.1 - 0.18 10.2 11.8 0.25 9.8 11.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SR-25 PF10500.9 GBG70290.1 - 1.3 8.6 14.5 3.2 7.3 14.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cep57_CLD_2 PF14197.6 GBG70291.1 - 0.26 11.4 0.6 1.6 8.8 0.1 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DPBB_1 PF03330.18 GBG70292.1 - 5.3e-15 55.5 0.7 1e-14 54.6 0.0 1.8 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG70292.1 - 3.5e-08 33.4 0.0 7.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Pollen allergen Y_Y_Y PF07495.13 GBG70293.1 - 0.00078 19.4 0.0 1.8 8.6 0.0 3.8 3 0 0 3 3 3 2 Y_Y_Y domain Big_3_3 PF13750.6 GBG70293.1 - 0.072 12.7 1.2 5.5 6.6 0.0 3.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) G8 PF10162.9 GBG70295.1 - 7.2e-26 90.7 0.0 1.4e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 G8 domain RT_RNaseH_2 PF17919.1 GBG70296.1 - 3.6e-27 94.3 0.0 1e-26 92.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70296.1 - 2.2e-24 85.7 0.0 5.1e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70296.1 - 1.2e-18 66.9 0.2 3e-18 65.7 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG70296.1 - 0.00011 22.4 0.2 0.00072 19.8 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein SoPB_HTH PF18090.1 GBG70296.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Centromere-binding protein HTH domain DUF4407 PF14362.6 GBG70296.1 - 0.69 9.2 7.2 1.3 8.3 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Senescence_reg PF04520.13 GBG70296.1 - 2.4 9.0 6.6 0.29 12.0 1.4 2.1 2 0 0 2 2 2 0 Senescence regulator TIG PF01833.24 GBG70297.1 - 6.1e-43 144.8 14.3 9.1e-12 44.9 0.1 7.4 7 0 0 7 7 7 6 IPT/TIG domain G8 PF10162.9 GBG70297.1 - 2e-31 108.6 0.1 7.8e-31 106.7 0.0 2.0 2 0 0 2 2 2 1 G8 domain RT_RNaseH_2 PF17919.1 GBG70297.1 - 7e-29 99.8 0.0 2.1e-28 98.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70297.1 - 7e-29 100.2 0.2 3.7e-28 97.9 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70297.1 - 3.1e-23 82.5 0.1 7.1e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70297.1 - 7.6e-11 42.0 0.2 2.5e-10 40.3 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain PA14 PF07691.12 GBG70297.1 - 0.0035 17.2 0.0 0.0094 15.8 0.0 1.7 1 0 0 1 1 1 1 PA14 domain Beta_helix PF13229.6 GBG70297.1 - 0.011 15.5 6.1 0.0086 15.9 3.0 2.2 1 1 1 2 2 2 0 Right handed beta helix region TFIIA PF03153.13 GBG70298.1 - 3.2 7.7 18.3 4.1 7.3 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH_2 PF17919.1 GBG70299.1 - 1.3e-25 89.3 0.0 2.4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70299.1 - 6.1e-21 74.7 0.0 1.2e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70299.1 - 7.6e-19 68.1 0.0 1.6e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG70299.1 - 1.5e-08 35.1 0.0 3.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70299.1 - 3.2e-08 34.0 0.0 6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG70299.1 - 4.3e-06 26.5 0.0 8.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG70299.1 - 4.4e-06 26.5 0.0 1.3e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease PaaX_C PF08223.11 GBG70299.1 - 0.03 14.6 0.2 0.12 12.7 0.0 2.0 1 1 1 2 2 2 0 PaaX-like protein C-terminal domain TIG PF01833.24 GBG70300.1 - 1.2e-26 92.6 16.9 8.9e-08 32.1 0.4 4.5 4 0 0 4 4 4 4 IPT/TIG domain PA-IIL PF07472.11 GBG70300.1 - 0.14 12.5 1.2 21 5.5 0.1 2.5 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) RVT_1 PF00078.27 GBG70301.1 - 1.3e-28 100.1 0.4 2.8e-28 99.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70301.1 - 3.2e-18 65.6 0.0 1.6e-17 63.4 0.0 2.2 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70301.1 - 1.4e-08 35.0 0.0 6.3e-08 32.8 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG70301.1 - 1.8e-06 27.8 0.0 3.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG70301.1 - 0.00018 22.0 0.8 0.0015 19.0 0.0 2.7 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70301.1 - 0.00031 21.3 0.0 0.0016 19.0 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease ZapB PF06005.12 GBG70301.1 - 0.0015 19.0 0.1 0.0015 19.0 0.1 3.9 3 1 0 3 3 2 1 Cell division protein ZapB Asp_protease PF09668.10 GBG70301.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.12 GBG70301.1 - 0.19 12.4 0.1 0.19 12.4 0.1 4.8 4 2 1 5 5 4 0 SlyX NPV_P10 PF05531.12 GBG70301.1 - 0.83 10.2 9.4 19 5.8 6.1 3.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4746 PF15928.5 GBG70301.1 - 3.4 7.0 8.1 6 6.2 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Retrotrans_gag PF03732.17 GBG70302.1 - 0.025 14.9 1.1 0.082 13.2 1.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Glyco_transf_64 PF09258.10 GBG70303.1 - 4.7e-64 216.0 0.0 6e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain SR-25 PF10500.9 GBG70303.1 - 6.7 6.3 22.9 12 5.4 22.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 GBG70304.1 - 4.3e-27 95.1 0.1 1.2e-26 93.6 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70304.1 - 6e-24 84.3 0.0 1.7e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70304.1 - 2e-23 82.3 0.0 5.7e-23 80.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG70304.1 - 4.2e-07 30.2 0.0 3e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG70304.1 - 5.9e-07 30.1 0.0 1.5e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG70304.1 - 1.1e-05 25.2 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG70304.1 - 1.9e-05 24.7 3.4 5e-05 23.3 3.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG70304.1 - 6e-05 23.5 0.0 0.00018 22.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease PAN_4 PF14295.6 GBG70304.1 - 0.004 17.0 4.8 0.0099 15.8 4.8 1.7 1 0 0 1 1 1 1 PAN domain Asp_protease PF09668.10 GBG70304.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG70304.1 - 0.096 13.0 0.0 0.34 11.2 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Stevor PF17410.2 GBG70305.1 - 0.037 13.6 4.3 0.054 13.0 4.3 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RelB_transactiv PF16181.5 GBG70305.1 - 0.068 13.4 0.1 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 RelB transactivation domain PAN_4 PF14295.6 GBG70306.1 - 0.00057 19.7 7.1 0.00057 19.7 6.2 1.6 1 1 0 1 1 1 1 PAN domain OppC_N PF12911.7 GBG70306.1 - 0.047 13.7 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2804 PF10974.8 GBG70306.1 - 0.06 12.9 0.1 0.075 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) PAN_4 PF14295.6 GBG70307.1 - 0.00048 20.0 4.8 0.00096 19.0 4.8 1.6 1 0 0 1 1 1 1 PAN domain OppC_N PF12911.7 GBG70307.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2804 PF10974.8 GBG70307.1 - 0.15 11.6 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) PAN_4 PF14295.6 GBG70308.1 - 0.00054 19.8 5.7 0.001 18.9 5.7 1.6 1 1 0 1 1 1 1 PAN domain OppC_N PF12911.7 GBG70308.1 - 0.07 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2804 PF10974.8 GBG70308.1 - 0.096 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) RT_RNaseH_2 PF17919.1 GBG70309.1 - 7.4e-35 119.0 0.0 1.5e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70309.1 - 1.3e-30 105.7 0.0 3e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70309.1 - 9.6e-18 64.1 0.1 2.1e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70309.1 - 4.2e-15 56.0 0.1 1.2e-13 51.3 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain GATase_4 PF13230.6 GBG70309.1 - 0.084 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Myb_DNA-bind_4 PF13837.6 GBG70310.1 - 2.7e-10 40.5 1.4 4.2e-10 39.9 0.6 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70310.1 - 0.00034 20.9 0.1 0.00089 19.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG70310.1 - 0.049 13.9 0.3 0.095 13.0 0.3 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG70310.1 - 0.38 10.8 5.9 0.13 12.4 1.2 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF1690 PF07956.11 GBG70313.1 - 2 8.8 10.0 2.6 8.5 8.7 1.8 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) BAF1_ABF1 PF04684.13 GBG70313.1 - 3.2 6.7 7.3 4.1 6.3 7.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PvlArgDC PF01862.16 GBG70313.1 - 6.3 6.6 6.0 7 6.4 0.0 2.8 2 1 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Pkinase PF00069.25 GBG70314.1 - 7.4e-17 61.6 0.0 9.2e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70314.1 - 6.4e-13 48.6 0.0 9.6e-13 48.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 GBG70315.1 - 7.4e-54 182.6 0.7 5.1e-30 104.6 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70315.1 - 1e-21 77.2 0.4 6.3e-21 74.6 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70315.1 - 2.4e-16 59.6 0.2 8.7e-16 57.8 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG70315.1 - 4.2e-13 49.2 0.0 5.3e-12 45.6 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG70315.1 - 2.1e-05 24.6 0.0 8.9e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger rve PF00665.26 GBG70315.1 - 0.00054 20.1 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain PTPlike_phytase PF14566.6 GBG70315.1 - 1.4 9.1 6.6 3.2 7.9 6.6 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate WxL PF13731.6 GBG70316.1 - 0.023 14.7 0.9 0.028 14.5 0.9 1.2 1 0 0 1 1 1 0 WxL domain surface cell wall-binding Integrase_H2C2 PF17921.1 GBG70317.1 - 8.6e-16 57.8 0.1 1.7e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70317.1 - 1.1e-11 44.9 0.0 5.9e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG70320.1 - 3e-27 95.0 0.0 7.4e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70320.1 - 2.6e-26 91.6 0.0 6.7e-26 90.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Snapin_Pallidin PF14712.6 GBG70320.1 - 0.012 16.1 0.1 0.041 14.3 0.0 1.9 2 0 0 2 2 2 0 Snapin/Pallidin DUF1378 PF07125.11 GBG70320.1 - 0.072 13.3 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) RT_RNaseH_2 PF17919.1 GBG70321.1 - 4.6e-32 110.0 0.0 7.7e-32 109.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70321.1 - 1e-27 96.5 0.0 1.8e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70321.1 - 2e-16 60.2 0.1 3.5e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2389 PF09493.10 GBG70321.1 - 0.086 13.5 0.2 1.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Tryptophan-rich protein (DUF2389) RT_RNaseH PF17917.1 GBG70323.1 - 8.3e-30 103.2 0.2 2.4e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70323.1 - 1.7e-29 101.8 0.0 4.9e-29 100.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70323.1 - 0.053 13.0 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 GBG70323.1 - 0.2 10.4 3.2 0.35 9.6 3.2 1.3 1 0 0 1 1 1 0 Presenilin Phage_GPO PF05929.11 GBG70323.1 - 0.22 11.1 0.1 0.22 11.1 0.1 3.1 2 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase ADP_ribosyl_GH PF03747.14 GBG70323.1 - 1.7 8.3 4.2 1.7 8.3 0.0 2.8 3 0 0 3 3 3 0 ADP-ribosylglycohydrolase DRY_EERY PF09750.9 GBG70323.1 - 3.4 7.9 11.4 7.2 6.9 0.0 2.9 2 0 0 2 2 2 0 Alternative splicing regulator gag-asp_proteas PF13975.6 GBG70324.1 - 4.6e-06 27.1 0.1 7.9e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70324.1 - 9.4e-06 26.2 0.1 1.6e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG70324.1 - 0.00021 21.1 0.1 0.00035 20.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF4360 PF14273.6 GBG70327.1 - 5e-35 121.0 0.1 5.6e-35 120.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Toxin_32 PF08120.11 GBG70328.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 Tamulustoxin family Plant_tran PF04827.14 GBG70329.1 - 0.0038 16.9 0.0 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 GBG70329.1 - 0.0041 16.8 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG70330.1 - 1.6e-25 90.0 0.2 2.8e-25 89.1 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG70330.1 - 5.7e-07 29.7 0.0 4e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG70330.1 - 0.0018 18.1 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG70330.1 - 0.0036 17.5 1.7 0.0055 17.0 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG70330.1 - 0.0073 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG70333.1 - 7.5e-27 93.3 0.0 1.2e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70333.1 - 1.9e-21 76.3 0.0 3.9e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70333.1 - 4.8e-07 29.5 0.0 7.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG70333.1 - 0.19 11.1 6.8 0.25 10.7 6.8 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG70333.1 - 0.38 9.0 7.0 0.54 8.5 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG70333.1 - 1.8 6.6 9.5 2.4 6.2 9.5 1.0 1 0 0 1 1 1 0 Nop14-like family Ribosomal_S25 PF03297.15 GBG70335.1 - 0.0012 19.0 9.3 0.0015 18.7 9.3 1.2 1 0 0 1 1 1 1 S25 ribosomal protein MDFI PF15316.6 GBG70335.1 - 0.0047 17.0 1.6 0.0053 16.9 1.6 1.1 1 0 0 1 1 1 1 MyoD family inhibitor Nro1 PF12753.7 GBG70335.1 - 0.03 13.3 2.7 0.031 13.3 2.7 1.0 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 AP3D1 PF06375.11 GBG70335.1 - 0.06 13.6 16.1 0.079 13.2 16.1 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Sec62 PF03839.16 GBG70335.1 - 0.063 12.8 5.0 0.061 12.8 5.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Protocadherin PF08374.11 GBG70335.1 - 0.078 12.9 4.2 0.081 12.9 4.2 1.1 1 0 0 1 1 1 0 Protocadherin HCO3_cotransp PF00955.21 GBG70335.1 - 0.14 11.0 0.1 0.16 10.8 0.1 1.0 1 0 0 1 1 1 0 HCO3- transporter family OAD_gamma PF04277.13 GBG70335.1 - 0.32 11.6 6.1 0.46 11.1 6.1 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3464 PF11947.8 GBG70335.1 - 0.43 10.3 6.7 0.51 10.1 6.7 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SMN PF06003.12 GBG70335.1 - 4 6.6 12.6 4.9 6.3 12.6 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Peptidase_S49_N PF08496.10 GBG70335.1 - 5.4 7.1 13.4 6.4 6.8 13.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TSGP1 PF07771.11 GBG70335.1 - 7.9 6.6 15.6 13 5.9 15.2 1.6 2 0 0 2 2 2 0 Tick salivary peptide group 1 Coilin_N PF15862.5 GBG70335.1 - 9.8 6.0 15.3 15 5.4 15.3 1.3 1 0 0 1 1 1 0 Coilin N-terminus Pkinase_Tyr PF07714.17 GBG70336.1 - 2e-22 79.8 0.0 3.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG70336.1 - 2.4e-19 69.7 0.0 2.4e-19 69.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 GBG70336.1 - 1.9e-09 38.0 5.2 6.7e-05 23.6 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG70336.1 - 0.0089 16.3 0.0 6.1 7.2 0.0 3.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain STAT_alpha PF01017.20 GBG70336.1 - 0.016 15.1 1.8 0.016 15.1 1.8 3.0 2 1 1 3 3 3 0 STAT protein, all-alpha domain Ldl_recept_a PF00057.18 GBG70337.1 - 4.9e-43 145.0 136.8 1.2e-08 35.0 11.3 11.6 10 1 0 11 11 11 9 Low-density lipoprotein receptor domain class A DDE_Tnp_4 PF13359.6 GBG70338.1 - 2.1e-08 34.0 0.0 3.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70338.1 - 0.00022 20.9 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein Ldl_recept_a PF00057.18 GBG70339.1 - 4.1e-07 30.1 18.9 1.1e-05 25.6 8.7 4.0 4 1 0 4 4 4 2 Low-density lipoprotein receptor domain class A Asp_protease_2 PF13650.6 GBG70341.1 - 0.13 12.9 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG70341.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Ldl_recept_a PF00057.18 GBG70342.1 - 8.9e-49 163.4 119.8 2.1e-08 34.2 6.5 11.3 9 2 1 11 11 11 10 Low-density lipoprotein receptor domain class A Pkinase_Tyr PF07714.17 GBG70343.1 - 5.9e-21 74.9 0.0 7.9e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG70343.1 - 1.7e-19 70.3 0.0 2.1e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ldl_recept_a PF00057.18 GBG70344.1 - 1e-38 131.2 127.2 2.1e-08 34.2 6.8 11.7 9 3 3 12 12 12 10 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 GBG70345.1 - 4.5e-41 138.8 135.7 3.2e-08 33.6 6.5 11.6 8 3 0 11 11 11 9 Low-density lipoprotein receptor domain class A RT_RNaseH_2 PF17919.1 GBG70345.1 - 1.8e-33 114.5 0.0 3e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70345.1 - 1.8e-31 108.6 0.0 3e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70345.1 - 2.3e-06 27.3 0.1 3.4e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG70347.1 - 3.3e-09 37.0 0.7 1.3e-07 31.9 0.4 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG70347.1 - 0.0027 17.8 0.9 0.0073 16.4 0.9 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70347.1 - 0.07 13.4 0.2 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF659 PF04937.15 GBG70348.1 - 5e-05 23.2 0.0 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Ldl_recept_a PF00057.18 GBG70350.1 - 1.4e-43 146.8 131.6 1.2e-08 35.0 11.3 11.7 10 1 0 11 11 11 9 Low-density lipoprotein receptor domain class A RB_A PF01858.17 GBG70354.1 - 0.026 14.4 0.8 0.09 12.6 0.7 1.8 1 1 0 1 1 1 0 Retinoblastoma-associated protein A domain tRNA_edit PF04073.15 GBG70354.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain Myb_DNA-bind_4 PF13837.6 GBG70355.1 - 1.4e-11 44.6 5.2 2.5e-11 43.8 5.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG70355.1 - 0.004 17.3 1.2 0.0088 16.2 1.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ACC_epsilon PF13822.6 GBG70355.1 - 0.1 13.3 1.7 0.32 11.7 1.7 1.8 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Myb_DNA-bind_3 PF12776.7 GBG70355.1 - 0.13 13.3 2.6 0.3 12.1 2.6 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG70355.1 - 0.16 12.3 1.7 0.3 11.4 1.7 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70355.1 - 0.38 11.1 4.5 0.35 11.2 1.8 2.2 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Glyco_transf_64 PF09258.10 GBG70356.1 - 9.2e-44 149.6 0.0 1.4e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 GBG70356.1 - 1.7e-06 27.8 2.7 0.00063 19.4 2.7 3.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GBG70356.1 - 0.22 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Apolipoprotein PF01442.18 GBG70357.1 - 7.9e-08 32.4 30.0 0.0012 18.7 16.6 2.7 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GBG70357.1 - 0.00021 21.8 41.9 0.17 12.4 11.3 4.9 3 2 0 3 3 3 2 YtxH-like protein DUF883 PF05957.13 GBG70357.1 - 0.0013 19.2 24.3 0.017 15.7 2.3 4.7 2 2 1 4 4 4 2 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 GBG70357.1 - 0.0018 18.4 10.4 0.0018 18.4 10.4 3.5 2 2 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) LEA_4 PF02987.16 GBG70357.1 - 0.018 15.1 10.7 0.018 15.1 10.7 6.2 4 2 4 8 8 8 0 Late embryogenesis abundant protein RR_TM4-6 PF06459.12 GBG70358.1 - 0.075 12.9 26.4 0.088 12.6 26.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 GBG70358.1 - 0.31 10.8 15.3 0.35 10.6 15.3 1.2 1 0 0 1 1 1 0 AAA domain DUF2052 PF09747.9 GBG70358.1 - 1 9.4 19.6 1.3 9.1 19.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SAPS PF04499.15 GBG70358.1 - 2.2 7.0 14.7 2.4 6.8 14.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 GBG70358.1 - 2.3 6.2 11.6 2.5 6.1 11.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 GBG70358.1 - 5.8 5.6 21.3 9 4.9 21.3 1.3 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG70358.1 - 9.1 4.4 23.9 10 4.3 23.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 GBG70358.1 - 9.6 5.1 12.9 11 4.9 12.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GREB1 PF15782.5 GBG70358.1 - 9.7 3.2 8.5 9.8 3.1 8.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RMI1_N PF08585.12 GBG70359.1 - 0.052 13.3 1.2 0.094 12.5 1.2 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein zf-CCHC PF00098.23 GBG70359.1 - 0.47 10.6 8.7 0.12 12.6 4.8 2.0 2 0 0 2 2 2 0 Zinc knuckle DUF2229 PF09989.9 GBG70359.1 - 0.5 10.0 3.3 0.77 9.4 3.3 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) zf-CCHC_2 PF13696.6 GBG70359.1 - 0.83 9.5 3.6 2.1 8.3 3.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DASH_Spc19 PF08287.11 GBG70359.1 - 1.3 8.9 16.5 0.81 9.6 14.5 1.6 1 1 0 1 1 1 0 Spc19 DUF4407 PF14362.6 GBG70359.1 - 2.2 7.6 6.2 3.7 6.8 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VSG_B PF13206.6 GBG70359.1 - 3.2 6.9 8.6 4.5 6.4 8.6 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF1682 PF07946.14 GBG70359.1 - 9.2 5.4 17.8 14 4.7 17.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pkinase PF00069.25 GBG70360.1 - 3.3e-10 39.8 0.0 3.8e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70360.1 - 8.4e-09 35.1 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG70361.1 - 1.4e-09 38.4 8.8 0.00044 21.0 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 GBG70361.1 - 0.0022 16.7 0.0 0.46 9.1 0.0 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Troponin PF00992.20 GBG70361.1 - 1.3 9.4 38.6 0.47 10.8 10.5 3.1 1 1 2 3 3 3 0 Troponin ATG16 PF08614.11 GBG70361.1 - 1.9 8.6 31.9 1.9 8.7 21.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.19 GBG70361.1 - 4.6 7.0 49.7 0.02 14.8 30.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3381 PF11861.8 GBG70362.1 - 8.9 6.1 28.8 1.3 8.8 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Pkinase_Tyr PF07714.17 GBG70363.1 - 4.1e-23 82.0 0.0 6.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG70363.1 - 3.5e-20 72.5 0.0 7.7e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG70363.1 - 1.3e-07 32.2 1.8 0.081 13.8 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat PKcGMP_CC PF16808.5 GBG70363.1 - 1.6 8.6 18.1 4.1 7.3 8.1 4.2 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SLC12 PF03522.15 GBG70364.1 - 9.3 5.1 8.6 11 4.9 8.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RE_AspBHI_N PF18062.1 GBG70365.1 - 0.012 15.2 0.0 5.5 6.5 0.0 2.5 1 1 1 2 2 2 0 Restriction endonuclease AspBHI N-terminal GIT_CC PF16559.5 GBG70365.1 - 0.2 11.6 6.1 0.074 12.9 2.1 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TT_ORF1 PF02956.14 GBG70366.1 - 0.16 10.6 4.2 0.16 10.6 4.2 1.2 1 0 0 1 1 1 0 TT viral orf 1 Nop53 PF07767.11 GBG70366.1 - 4.3 6.6 42.0 6.8 6.0 42.0 1.3 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNA_polI_A34 PF08208.11 GBG70366.1 - 10 6.2 33.3 12 5.9 33.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ribosomal_S11 PF00411.19 GBG70367.1 - 1.8e-36 124.8 1.6 2.2e-36 124.6 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 GBG70367.1 - 0.039 14.2 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) RVT_1 PF00078.27 GBG70368.1 - 1.6e-26 93.2 0.0 3e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70368.1 - 5.9e-21 74.4 0.0 4.1e-15 55.6 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70368.1 - 3.4e-10 40.2 0.0 1.1e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG70368.1 - 7.1e-06 26.7 3.9 0.77 10.7 0.0 5.9 6 0 0 6 6 6 1 WD domain, G-beta repeat CobT PF06213.12 GBG70369.1 - 1.4 8.2 6.9 1.5 8.1 6.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4637 PF15470.6 GBG70369.1 - 1.7 8.3 7.8 1.9 8.2 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Paf1 PF03985.13 GBG70369.1 - 2.2 7.2 8.0 2.2 7.2 8.0 1.0 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.6 GBG70369.1 - 3.7 7.2 8.3 4.5 6.9 8.3 1.1 1 0 0 1 1 1 0 FAM176 family Ribosomal_60s PF00428.19 GBG70369.1 - 5.9 7.6 16.2 12 6.6 16.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein WRNPLPNID PF15017.6 GBG70369.1 - 5.9 7.8 14.1 11 7.0 14.1 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box CDC45 PF02724.14 GBG70369.1 - 7.3 4.7 6.1 8 4.6 6.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG70369.1 - 9.4 4.2 10.8 10 4.1 10.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 GBG70369.1 - 9.9 6.6 11.6 14 6.1 11.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Fib_alpha PF08702.10 GBG70370.1 - 0.0048 17.1 2.7 0.0048 17.1 2.7 2.1 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family WD40 PF00400.32 GBG70370.1 - 0.011 16.5 5.3 1.4 9.9 0.2 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat ERM PF00769.19 GBG70370.1 - 6 6.6 34.5 0.55 10.0 17.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cwf_Cwc_15 PF04889.12 GBG70371.1 - 0.018 14.8 16.4 0.018 14.8 16.4 2.2 1 1 1 2 2 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 GBG70371.1 - 0.021 15.2 15.2 0.021 15.2 15.2 3.1 2 1 1 3 3 2 0 Centromere protein B dimerisation domain SDA1 PF05285.12 GBG70371.1 - 0.099 12.1 36.0 0.11 11.8 36.0 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 GBG70371.1 - 0.13 11.6 46.3 0.31 10.3 24.7 2.1 2 0 0 2 2 2 0 NOA36 protein BUD22 PF09073.10 GBG70371.1 - 1.2 8.4 31.4 1.4 8.2 31.4 1.1 1 0 0 1 1 1 0 BUD22 V_ATPase_I PF01496.19 GBG70371.1 - 1.3 6.8 9.1 1.6 6.5 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nop14 PF04147.12 GBG70371.1 - 1.4 7.0 37.9 1.7 6.8 37.9 1.1 1 0 0 1 1 1 0 Nop14-like family Connexin PF00029.19 GBG70371.1 - 2.6 7.7 6.1 3.4 7.4 6.1 1.2 1 0 0 1 1 1 0 Connexin FRQ PF09421.10 GBG70371.1 - 6.7 4.6 23.2 7.7 4.4 23.2 1.1 1 0 0 1 1 1 0 Frequency clock protein Tankyrase_bdg_C PF15327.6 GBG70371.1 - 7.8 6.9 16.1 4.9 7.6 14.8 1.3 1 1 0 1 1 1 0 Tankyrase binding protein C terminal domain RPN2_C PF18004.1 GBG70371.1 - 8.8 6.2 22.2 0.94 9.4 17.3 1.7 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain IL31 PF15209.6 GBG70373.1 - 0.027 14.2 0.0 4.9 6.9 0.0 2.4 2 1 0 2 2 2 0 Interleukin 31 DASH_Dad4 PF08650.10 GBG70373.1 - 0.055 13.4 1.8 12 6.0 0.1 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad4 SlyX PF04102.12 GBG70373.1 - 0.07 13.7 1.6 28 5.4 1.5 3.3 3 1 0 3 3 3 0 SlyX Snapin_Pallidin PF14712.6 GBG70373.1 - 0.42 11.1 6.9 13 6.3 1.6 2.9 3 0 0 3 3 3 0 Snapin/Pallidin LPP PF04728.13 GBG70373.1 - 1.1 9.7 5.5 15 6.0 0.3 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper RVT_1 PF00078.27 GBG70374.1 - 1.3e-26 93.5 0.0 1.8e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SpoIIIAH PF12685.7 GBG70374.1 - 0.0039 17.1 2.8 0.0054 16.6 2.8 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein RVP_2 PF08284.11 GBG70374.1 - 0.022 14.5 0.2 0.066 13.0 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease SpoIIP PF07454.11 GBG70374.1 - 0.079 12.4 7.8 0.12 11.8 7.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FHIPEP PF00771.20 GBG70374.1 - 0.13 10.7 1.3 0.19 10.2 1.3 1.2 1 0 0 1 1 1 0 FHIPEP family DDHD PF02862.17 GBG70374.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 DDHD domain Eapp_C PF10238.9 GBG70374.1 - 0.24 11.5 3.0 0.44 10.6 2.3 1.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein RNA_polI_A34 PF08208.11 GBG70374.1 - 0.62 10.1 23.1 0.98 9.5 23.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF913 PF06025.12 GBG70374.1 - 0.67 8.9 6.2 1.2 8.0 6.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 GBG70374.1 - 1.2 7.1 28.9 1.7 6.6 28.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 GBG70374.1 - 1.5 8.9 11.4 2.7 8.2 11.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 GBG70374.1 - 1.8 8.3 8.0 2.7 7.7 8.0 1.2 1 0 0 1 1 1 0 Connexin PPL5 PF18168.1 GBG70374.1 - 2.6 7.3 7.2 3.8 6.7 7.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 V_ATPase_I PF01496.19 GBG70374.1 - 3.3 5.5 10.4 5 4.9 10.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XAP5 PF04921.14 GBG70374.1 - 3.6 7.3 11.9 5.8 6.7 11.9 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Ferlin_C PF16165.5 GBG70374.1 - 6.1 6.8 8.5 13 5.7 8.5 1.5 1 0 0 1 1 1 0 Ferlin C-terminus SDA1 PF05285.12 GBG70374.1 - 6.1 6.2 29.1 9.2 5.6 29.1 1.2 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 GBG70374.1 - 7.2 6.3 21.1 11 5.7 21.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 GBG70374.1 - 9.3 4.9 14.9 14 4.3 14.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 GBG70374.1 - 9.5 5.3 7.0 13 4.8 7.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 GBG70375.1 - 0.016 15.2 8.6 0.03 14.3 8.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CSRNP_N PF16019.5 GBG70375.1 - 0.74 9.7 5.6 1.5 8.7 5.6 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Presenilin PF01080.17 GBG70375.1 - 7 5.3 10.2 13 4.4 10.2 1.4 1 0 0 1 1 1 0 Presenilin U79_P34 PF03064.16 GBG70376.1 - 1.6 8.0 12.5 0.91 8.8 10.3 1.6 2 0 0 2 2 2 0 HSV U79 / HCMV P34 LRR_4 PF12799.7 GBG70377.1 - 2e-10 40.7 0.1 0.62 10.6 0.0 6.7 7 1 1 8 8 8 4 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG70377.1 - 3.2e-05 23.7 0.1 8.3e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG70377.1 - 0.0015 18.3 0.3 0.0048 16.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 GBG70377.1 - 0.035 14.1 1.1 23 5.4 0.4 5.1 5 0 0 5 5 5 0 Leucine Rich repeat RT_RNaseH_2 PF17919.1 GBG70378.1 - 4.5e-06 26.6 0.0 9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70378.1 - 0.0015 18.8 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70378.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG70379.1 - 3.1e-37 128.3 0.0 6.6e-37 127.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG70379.1 - 4.6e-34 118.0 0.0 1e-33 116.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 GBG70381.1 - 3.2e-28 98.8 0.1 1e-20 74.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70381.1 - 5.9e-26 91.3 0.0 3.8e-17 62.4 0.0 2.7 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG70381.1 - 0.058 12.2 0.1 0.24 10.1 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 GBG70381.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Phage_holin_2_4 PF16082.5 GBG70381.1 - 0.096 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF2076 PF09849.9 GBG70381.1 - 0.27 11.2 0.2 0.52 10.3 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PMP1_2 PF08114.11 GBG70381.1 - 0.33 10.7 2.0 0.64 9.8 2.0 1.5 1 0 0 1 1 1 0 ATPase proteolipid family SKG6 PF08693.10 GBG70381.1 - 7.5 6.1 7.9 14 5.2 7.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Myb_DNA-bind_4 PF13837.6 GBG70382.1 - 3e-07 30.7 0.3 5.5e-07 29.9 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pkinase_Tyr PF07714.17 GBG70383.1 - 5.8e-37 127.4 0.0 1.6e-36 125.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG70383.1 - 5.6e-35 121.0 0.0 9.2e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG70383.1 - 0.097 12.6 0.0 0.5 10.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GBG70384.1 - 1.2e-37 129.7 0.0 4.3e-37 127.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG70384.1 - 2.1e-34 119.1 0.0 3.6e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PRIMA1 PF16101.5 GBG70384.1 - 0.049 13.7 0.2 0.049 13.7 0.2 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 APH PF01636.23 GBG70384.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF659 PF04937.15 GBG70385.1 - 4.9e-30 104.4 0.3 7.2e-30 103.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PilN PF05137.13 GBG70386.1 - 0.0035 17.4 0.2 0.0068 16.5 0.2 1.4 1 0 0 1 1 1 1 Fimbrial assembly protein (PilN) Pkinase_Tyr PF07714.17 GBG70387.1 - 8.5e-38 130.1 0.0 1.2e-37 129.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG70387.1 - 4.5e-34 118.0 0.0 6.8e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PRIMA1 PF16101.5 GBG70387.1 - 0.048 13.7 0.2 0.082 12.9 0.2 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 GRA6 PF05084.13 GBG70387.1 - 0.058 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) EphA2_TM PF14575.6 GBG70387.1 - 0.17 12.8 0.0 0.3 12.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 GBG70387.1 - 0.54 10.1 5.4 1.1 9.1 5.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase_Tyr PF07714.17 GBG70388.1 - 1.1e-36 126.5 0.0 2.7e-36 125.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG70388.1 - 8.2e-33 113.9 0.0 1.4e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG70388.1 - 0.15 12.0 0.0 0.49 10.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family GRA6 PF05084.13 GBG70388.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) RT_RNaseH_2 PF17919.1 GBG70389.1 - 2.8e-23 81.8 0.0 6e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70389.1 - 6.9e-14 52.0 0.0 1.5e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70389.1 - 4.3e-08 32.9 0.1 7.1e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BURP PF03181.15 GBG70389.1 - 0.019 14.6 0.4 0.044 13.4 0.4 1.5 1 0 0 1 1 1 0 BURP domain Pkinase_Tyr PF07714.17 GBG70390.1 - 1.7e-38 132.4 0.0 2.5e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG70390.1 - 5.2e-36 124.4 0.0 7.4e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG70390.1 - 0.025 14.5 0.0 0.073 13.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG70390.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF659 PF04937.15 GBG70391.1 - 1.1e-13 51.4 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4748 PF15932.5 GBG70391.1 - 0.18 11.6 0.4 2.4 7.9 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) Integrase_H2C2 PF17921.1 GBG70392.1 - 8.3e-15 54.7 0.1 2.4e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG70392.1 - 1.9e-11 44.2 0.0 4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70392.1 - 5.5e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG70392.1 - 0.013 16.2 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG70393.1 - 2.4e-07 31.2 0.1 6.4e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG70393.1 - 0.00035 20.3 0.1 0.00075 19.3 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70393.1 - 0.002 18.8 0.1 0.0079 16.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG70393.1 - 0.15 11.9 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease BUD22 PF09073.10 GBG70393.1 - 0.28 10.5 30.6 0.71 9.1 24.3 2.2 2 0 0 2 2 2 0 BUD22 Na_trans_assoc PF06512.13 GBG70393.1 - 0.36 11.1 21.8 0.17 12.1 19.0 1.9 2 0 0 2 2 2 0 Sodium ion transport-associated TFIIF_alpha PF05793.12 GBG70393.1 - 0.45 9.1 29.4 0.73 8.4 29.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 GBG70393.1 - 3.4 5.7 20.0 6.7 4.7 20.0 1.5 1 0 0 1 1 1 0 DNA polymerase phi LAP1C PF05609.12 GBG70393.1 - 3.4 6.6 15.4 6.3 5.8 15.4 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CobT PF06213.12 GBG70393.1 - 5.2 6.4 22.6 8.5 5.7 22.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAPS PF04499.15 GBG70393.1 - 9.4 4.9 9.2 15 4.3 9.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RT_RNaseH PF17917.1 GBG70395.1 - 4.1e-23 81.7 0.1 1.1e-22 80.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70395.1 - 2.4e-22 78.8 0.0 4.8e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70395.1 - 8.2e-17 61.1 0.3 1.9e-16 59.9 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG70395.1 - 4.9e-08 32.8 0.0 8.7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70395.1 - 7.3e-08 33.0 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70395.1 - 6.4e-06 26.6 0.0 1.4e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG70395.1 - 9.2e-05 22.1 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tudor-knot PF11717.8 GBG70395.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG70395.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG70395.1 - 0.02 14.8 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain SRPRB PF09439.10 GBG70396.1 - 2.7e-38 131.2 0.0 3.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 GBG70396.1 - 6.3e-14 51.8 0.0 2e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GBG70396.1 - 6.7e-07 29.0 0.0 5e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GBG70396.1 - 1.6e-06 28.2 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 GBG70396.1 - 1.4e-05 25.3 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 GBG70396.1 - 0.0005 19.9 0.1 0.011 15.5 0.0 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 GBG70396.1 - 0.0012 18.8 0.2 0.18 11.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 GBG70396.1 - 0.0044 16.4 0.1 0.017 14.5 0.1 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GBG70396.1 - 0.0061 16.1 0.0 0.041 13.4 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 GBG70396.1 - 0.02 15.4 0.0 0.032 14.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 GBG70396.1 - 0.052 13.5 0.1 0.16 11.9 0.1 1.8 1 1 0 1 1 1 0 NACHT domain PEPCK_ATP PF01293.20 GBG70396.1 - 0.083 11.6 0.6 0.12 11.0 0.6 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 GBG70396.1 - 0.086 13.2 0.7 2.3 8.6 0.7 2.5 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 GBG70396.1 - 0.09 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Ras family TsaE PF02367.17 GBG70396.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Phage_holin_4_2 PF04020.13 GBG70397.1 - 0.032 14.9 4.4 0.061 14.0 4.4 1.5 1 0 0 1 1 1 0 Mycobacterial 4 TMS phage holin, superfamily IV DUF5320 PF17253.2 GBG70399.1 - 0.027 15.5 0.5 0.043 14.9 0.3 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5320) DDE_Tnp_4 PF13359.6 GBG70400.1 - 1.9e-11 43.9 0.0 5.9e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70400.1 - 7.9e-05 22.3 0.0 0.0002 21.0 0.0 1.7 2 0 0 2 2 2 1 Plant transposon protein HTH_Tnp_Mu_1 PF02316.16 GBG70400.1 - 0.017 15.3 0.2 0.037 14.2 0.2 1.5 1 0 0 1 1 1 0 Mu DNA-binding domain RVT_1 PF00078.27 GBG70400.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AdoHcyase PF05221.17 GBG70401.1 - 1.7e-145 483.8 0.0 1.9e-145 483.6 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GBG70401.1 - 9.8e-82 272.8 2.5 1.5e-81 272.2 2.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GBG70401.1 - 6.6e-06 25.6 0.3 1.2e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GBG70401.1 - 0.00039 20.0 0.2 0.00091 18.8 0.2 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 GBG70401.1 - 0.0014 18.9 0.1 0.0036 17.5 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 GBG70401.1 - 0.066 13.3 0.4 0.18 11.9 0.2 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 GBG70401.1 - 0.083 12.8 0.5 0.38 10.6 0.3 2.0 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GBG70401.1 - 0.11 13.0 0.3 0.63 10.7 0.2 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RVT_1 PF00078.27 GBG70402.1 - 2e-28 99.5 0.1 4e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70402.1 - 4.9e-24 84.3 0.0 1.4e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70402.1 - 1e-22 80.4 0.0 2.9e-22 78.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70402.1 - 2.3e-17 62.8 0.3 2.3e-17 62.8 0.3 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG70402.1 - 6.1e-11 42.6 0.0 3.3e-10 40.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG70402.1 - 1.8e-07 31.7 0.0 5.3e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70402.1 - 1.1e-06 29.0 0.0 3.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG70402.1 - 8.9e-06 25.5 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG70402.1 - 0.0027 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG70402.1 - 0.0036 17.6 1.4 0.11 12.8 0.0 3.6 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG70402.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger CLZ PF16526.5 GBG70402.1 - 4.8 7.6 9.0 3.4 8.1 0.6 3.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pam16 PF03656.13 GBG70403.1 - 6.7e-20 71.4 0.3 7.1e-20 71.3 0.3 1.0 1 0 0 1 1 1 1 Pam16 Phage_capsid PF05065.13 GBG70403.1 - 0.073 12.4 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Phage capsid family DUF4127 PF13552.6 GBG70404.1 - 0.036 12.7 7.4 0.063 11.9 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) gag-asp_proteas PF13975.6 GBG70405.1 - 7.5e-06 26.4 0.0 2.7e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70405.1 - 0.00019 22.0 0.0 0.00038 21.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG70405.1 - 0.00066 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG70405.1 - 0.0076 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease SRP54 PF00448.22 GBG70405.1 - 0.057 13.0 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DnaJ PF00226.31 GBG70407.1 - 3.1e-23 81.7 3.5 5.9e-23 80.8 3.5 1.5 1 0 0 1 1 1 1 DnaJ domain Sulf_transp PF04143.14 GBG70408.1 - 3.3e-09 36.8 29.7 8.7e-08 32.1 13.7 3.9 3 1 1 4 4 4 3 Sulphur transport DDE_Tnp_4 PF13359.6 GBG70409.1 - 0.0008 19.1 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SRP-alpha_N PF04086.13 GBG70410.1 - 1.1 9.1 34.3 1.4 8.7 34.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal adh_short_C2 PF13561.6 GBG70412.1 - 7.6e-46 156.5 0.3 1.1e-45 156.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GBG70412.1 - 9.4e-40 136.2 0.1 1.3e-39 135.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GBG70412.1 - 2.8e-06 27.4 0.2 2.8e-06 27.4 0.2 1.5 2 0 0 2 2 2 1 KR domain Pyr_redox PF00070.27 GBG70412.1 - 0.021 15.4 0.5 0.067 13.8 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 GBG70413.1 - 4.7e-37 127.8 0.9 1e-34 120.2 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GBG70413.1 - 1.9e-30 105.8 0.9 1.1e-20 74.0 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase Pyr_redox PF00070.27 GBG70413.1 - 0.022 15.3 0.8 0.068 13.7 0.6 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 GBG70413.1 - 0.43 10.5 4.4 0.089 12.7 0.8 1.6 2 0 0 2 2 2 0 KR domain Myb_DNA-bind_4 PF13837.6 GBG70414.1 - 6.6e-09 36.0 2.3 1.1e-08 35.3 2.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SOTI PF17079.5 GBG70414.1 - 0.083 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Male-specific protein scotti Myb_DNA-binding PF00249.31 GBG70414.1 - 0.12 12.6 1.6 0.46 10.7 1.6 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain Thioredoxin_7 PF13899.6 GBG70415.1 - 5.6e-13 48.9 0.0 1.3e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 GBG70415.1 - 5.1e-11 42.6 0.0 9.4e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain UIM PF02809.20 GBG70415.1 - 0.0016 18.2 0.9 0.0034 17.2 0.9 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif TetR_C_15 PF17918.1 GBG70415.1 - 0.17 12.6 1.1 0.32 11.8 1.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Amino_oxidase PF01593.24 GBG70416.1 - 1.3e-17 64.3 0.0 1.7e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG70416.1 - 3.8e-12 46.3 0.4 1e-11 44.9 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GBG70416.1 - 9.2e-09 34.9 0.8 0.00022 20.5 0.5 2.6 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 GBG70416.1 - 1.7e-08 34.5 2.2 1.1e-07 31.8 2.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GBG70416.1 - 0.00014 20.7 0.7 0.35 9.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 GBG70416.1 - 0.0027 17.0 0.3 0.016 14.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GBG70416.1 - 0.0046 16.2 0.2 0.0086 15.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 GBG70416.1 - 0.022 14.1 1.3 0.022 14.1 1.3 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GBG70416.1 - 0.032 13.5 1.8 0.059 12.6 1.8 1.4 1 0 0 1 1 1 0 FAD binding domain GDI PF00996.18 GBG70416.1 - 0.044 12.3 0.0 0.74 8.3 0.0 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox PF00070.27 GBG70416.1 - 0.37 11.4 2.5 2.2 8.9 1.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RT_RNaseH PF17917.1 GBG70417.1 - 5.2e-30 103.8 0.0 1.3e-29 102.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70417.1 - 3e-28 97.8 0.0 8.1e-28 96.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70417.1 - 8.1e-13 48.4 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG70417.1 - 0.027 14.1 9.0 0.27 10.8 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PA26 PF04636.13 GBG70417.1 - 0.93 8.3 9.5 1.4 7.7 9.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4407 PF14362.6 GBG70417.1 - 9.3 5.5 8.2 26 4.0 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CCHC PF00098.23 GBG70418.1 - 1.6e-05 24.8 3.1 2.4e-05 24.2 3.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG70418.1 - 0.013 15.3 2.8 0.02 14.7 2.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Syntaxin_2 PF14523.6 GBG70418.1 - 3.5 8.0 4.9 0.74 10.2 0.1 2.1 3 0 0 3 3 3 0 Syntaxin-like protein RVP_2 PF08284.11 GBG70419.1 - 0.0034 17.1 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG70422.1 - 0.00022 21.1 1.4 0.00046 20.1 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle WW_FCH_linker PF16623.5 GBG70422.1 - 0.0077 17.0 0.3 0.0077 17.0 0.3 2.3 2 0 0 2 2 2 1 Unstructured linker region between on GAS7 protein zf-CCHC_4 PF14392.6 GBG70422.1 - 0.021 14.6 0.6 0.052 13.3 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle HSBP1 PF06825.12 GBG70422.1 - 0.11 12.3 4.2 6.9 6.6 0.0 3.0 3 1 0 3 3 3 0 Heat shock factor binding protein 1 DXP_synthase_N PF13292.6 GBG70422.1 - 0.37 10.0 4.4 0.07 12.3 0.7 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase YojJ PF10372.9 GBG70422.1 - 0.89 9.7 3.2 3.9 7.7 3.2 2.1 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus DASH_Spc19 PF08287.11 GBG70422.1 - 1.2 9.1 23.8 0.19 11.6 11.8 2.1 2 0 0 2 2 2 0 Spc19 DUF2115 PF09888.9 GBG70422.1 - 2.3 8.7 12.0 0.27 11.7 6.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) BET PF17035.5 GBG70423.1 - 0.0084 16.3 0.3 0.0084 16.3 0.3 1.9 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation MIP-T3_C PF17749.1 GBG70423.1 - 0.12 12.4 11.3 0.023 14.6 8.0 1.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4962 PF16332.5 GBG70423.1 - 0.54 8.7 5.1 0.74 8.3 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) RVT_1 PF00078.27 GBG70424.1 - 1.8e-22 80.0 0.0 2.9e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70424.1 - 1.7e-12 47.2 0.1 3.7e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70424.1 - 5.1e-12 46.0 0.0 1.6e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70424.1 - 0.00037 20.6 0.0 0.00073 19.7 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG70424.1 - 0.0068 17.0 0.0 0.091 13.4 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease TCP PF03634.13 GBG70425.1 - 7.9e-26 91.5 0.0 3.1e-25 89.5 0.0 2.1 1 1 0 1 1 1 1 TCP family transcription factor DEK_C PF08766.11 GBG70427.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain RVT_1 PF00078.27 GBG70429.1 - 6.2e-33 114.2 0.0 9.3e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70429.1 - 1.7e-23 82.5 0.0 1.7e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70429.1 - 1e-11 45.0 0.0 3.1e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Apc13p PF05839.11 GBG70429.1 - 0.0057 16.8 0.4 0.018 15.2 0.4 1.9 1 0 0 1 1 1 1 Apc13p protein Cortex-I_coil PF09304.10 GBG70429.1 - 0.19 11.9 2.5 0.43 10.8 2.5 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil Myb_DNA-bind_4 PF13837.6 GBG70430.1 - 2e-05 24.9 5.1 3.9e-05 23.9 5.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70430.1 - 0.034 14.5 1.5 0.085 13.2 1.5 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG70430.1 - 0.038 14.1 2.4 0.085 12.9 2.4 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain CDC45 PF02724.14 GBG70430.1 - 1.9 6.7 6.3 2.6 6.2 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Stig1 PF04885.13 GBG70433.1 - 1.8e-48 164.6 144.5 1.2e-14 55.0 29.3 5.1 1 1 4 5 5 5 5 Stigma-specific protein, Stig1 RVT_1 PF00078.27 GBG70434.1 - 2e-32 112.5 0.1 3.4e-32 111.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70434.1 - 1.4e-28 98.9 0.0 3e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70434.1 - 3.4e-24 85.2 0.2 1.2e-23 83.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG70434.1 - 0.00025 20.8 0.0 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70434.1 - 0.00026 21.5 0.0 0.00077 20.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70434.1 - 0.00036 21.0 0.0 0.00083 19.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rhamno_transf PF11316.8 GBG70434.1 - 0.034 13.5 0.5 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 Putative rhamnosyl transferase zf-CCHC PF00098.23 GBG70435.1 - 1.8e-08 34.1 1.4 1.8e-08 34.1 1.4 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG70435.1 - 0.00033 20.4 2.6 0.00054 19.7 2.0 1.7 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG70435.1 - 0.0054 17.3 0.0 0.014 15.9 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70435.1 - 0.012 16.3 0.0 0.032 14.9 0.0 1.7 2 0 0 2 2 2 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG70436.1 - 1.1e-19 70.3 0.6 2.5e-19 69.1 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG70436.1 - 6.1e-19 68.2 0.0 1.4e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70436.1 - 2.8e-17 62.6 0.0 6.1e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG70436.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve PF00665.26 GBG70437.1 - 2.5e-10 40.6 0.1 6.5e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG70437.1 - 4.1e-05 23.4 0.1 8.3e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG70437.1 - 0.005 17.1 0.3 0.005 17.1 0.3 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG70437.1 - 0.16 11.8 1.3 0.45 10.3 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) tRNA-synt_2c PF01411.19 GBG70438.1 - 2.4e-150 501.7 0.0 3.2e-150 501.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) zf-ZPR1 PF03367.13 GBG70438.1 - 6.6e-110 364.1 0.0 9.7e-55 184.8 0.0 2.4 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DiS_P_DiS PF06750.13 GBG70438.1 - 2.1 8.5 4.5 15 5.8 0.4 2.8 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Fib_alpha PF08702.10 GBG70439.1 - 0.022 14.9 1.8 0.31 11.2 0.6 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2199 PF09965.9 GBG70439.1 - 0.03 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) DUF4407 PF14362.6 GBG70439.1 - 0.41 9.9 10.6 0.62 9.4 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COMP PF11598.8 GBG70439.1 - 0.45 11.0 2.7 8.1 7.0 0.9 2.6 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein zf-ZPR1 PF03367.13 GBG70440.1 - 3.8e-81 270.6 0.0 5.5e-46 156.3 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain gag-asp_proteas PF13975.6 GBG70441.1 - 1.4e-06 28.8 0.1 3.1e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70441.1 - 0.00011 22.7 0.1 0.00026 21.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG70441.1 - 0.0014 18.4 0.1 0.0022 17.8 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG70441.1 - 0.026 14.3 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG70442.1 - 0.0007 19.8 0.0 0.0019 18.4 0.0 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein UpxZ PF06603.11 GBG70442.1 - 0.084 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists DUF659 PF04937.15 GBG70443.1 - 3.4e-17 62.7 0.0 6e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Med21 PF11221.8 GBG70444.1 - 4e-22 79.0 0.1 8.7e-22 77.9 0.1 1.5 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Phage_GP20 PF06810.11 GBG70444.1 - 0.0079 16.0 0.3 0.011 15.6 0.3 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 GAF_3 PF13492.6 GBG70444.1 - 0.015 15.6 0.2 0.33 11.3 0.5 2.0 1 1 1 2 2 2 0 GAF domain DUF3763 PF12592.8 GBG70444.1 - 0.02 14.9 0.1 0.042 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) YgaB PF14182.6 GBG70444.1 - 0.024 15.0 0.8 0.052 14.0 0.8 1.5 1 0 0 1 1 1 0 YgaB-like protein FliT PF05400.13 GBG70444.1 - 0.053 14.3 1.9 0.057 14.2 0.9 1.6 2 0 0 2 2 2 0 Flagellar protein FliT CAP_N PF01213.19 GBG70444.1 - 0.63 9.5 5.8 0.33 10.4 3.9 1.6 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Tim44 PF04280.15 GBG70445.1 - 4.5e-12 46.3 0.3 1.8e-10 41.1 0.1 2.3 2 0 0 2 2 2 2 Tim44-like domain DUF321 PF03778.13 GBG70448.1 - 0.0036 16.9 0.1 0.0064 16.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF321) RVT_1 PF00078.27 GBG70449.1 - 3.4e-24 85.6 0.0 5.6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG70449.1 - 4e-06 27.4 0.0 1.6e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70449.1 - 8.3e-05 23.1 0.0 0.00024 21.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG70449.1 - 8.9e-05 22.3 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG70449.1 - 0.00035 20.8 2.4 0.049 13.9 0.0 3.6 3 0 0 3 3 3 1 Retrotransposon gag protein DUF2781 PF10914.8 GBG70449.1 - 0.089 13.2 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) PC4 PF02229.16 GBG70450.1 - 5.4e-21 74.0 0.1 6.9e-21 73.6 0.1 1.1 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Bacteroid_pep PF14406.6 GBG70453.1 - 0.054 13.9 0.1 1.4 9.4 0.1 2.2 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Bacteroidetes TPR_7 PF13176.6 GBG70453.1 - 3.1 8.0 6.4 16 5.8 4.2 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Integrase_H2C2 PF17921.1 GBG70454.1 - 3.9e-14 52.5 0.2 8.9e-14 51.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG70454.1 - 0.0011 19.1 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RNase_H2_suC PF08615.11 GBG70454.1 - 0.083 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Zip PF02535.22 GBG70454.1 - 0.52 9.5 2.5 0.72 9.0 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 GBG70454.1 - 0.63 8.3 15.0 0.83 7.9 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 GBG70454.1 - 1.2 7.2 4.7 1.7 6.6 4.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 GBG70454.1 - 1.2 8.4 17.6 2.6 7.3 17.6 1.6 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 GBG70454.1 - 2.5 7.9 8.8 4.1 7.2 8.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region IFT57 PF10498.9 GBG70454.1 - 2.6 6.9 13.6 3.9 6.3 13.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RXT2_N PF08595.11 GBG70454.1 - 2.7 8.0 10.9 4.9 7.2 10.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 GBG70454.1 - 4.5 7.7 19.9 16 5.9 19.9 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PPP4R2 PF09184.11 GBG70454.1 - 5.2 6.6 15.4 8.8 5.8 15.4 1.2 1 0 0 1 1 1 0 PPP4R2 Nucleo_P87 PF07267.11 GBG70454.1 - 5.3 5.8 16.7 8.8 5.0 16.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SDA1 PF05285.12 GBG70454.1 - 5.6 6.3 22.3 8.7 5.7 22.3 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG70454.1 - 5.8 6.6 22.6 9.9 5.8 22.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFB6 PF17110.5 GBG70454.1 - 6.9 6.4 6.8 13 5.5 6.8 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RPN2_C PF18004.1 GBG70454.1 - 9 6.2 9.7 17 5.3 9.7 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Dimer_Tnp_hAT PF05699.14 GBG70455.1 - 3.7e-05 23.4 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Exo_endo_phos PF03372.23 GBG70457.1 - 8.1e-11 41.9 0.2 2.1e-10 40.6 0.2 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 GBG70457.1 - 4.4e-08 33.7 1.3 4.4e-08 33.7 1.3 2.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 GBG70457.1 - 0.0008 19.0 0.3 0.65 9.5 0.1 2.7 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 GBG70457.1 - 0.0038 17.1 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DNA_pol_lambd_f PF10391.9 GBG70457.1 - 0.095 12.5 1.0 1.4 8.8 0.2 2.9 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda RT_RNaseH_2 PF17919.1 GBG70458.1 - 1.9e-25 88.8 0.0 3.1e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70458.1 - 6.1e-23 81.1 0.0 1.1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70458.1 - 4.4e-11 42.7 0.1 7.1e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Thioredoxin PF00085.20 GBG70459.1 - 3e-05 24.0 0.0 4.1e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Alba PF01918.21 GBG70460.1 - 8.2e-13 48.0 0.3 1.5e-12 47.1 0.3 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 GBG70460.1 - 7.5e-05 22.7 0.3 7.5e-05 22.7 0.3 2.5 2 0 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P OsmC PF02566.19 GBG70460.1 - 0.1 13.1 0.1 0.19 12.3 0.1 1.3 1 0 0 1 1 1 0 OsmC-like protein Presenilin PF01080.17 GBG70460.1 - 0.4 9.4 11.0 0.53 9.0 11.0 1.2 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.13 GBG70460.1 - 0.69 8.4 14.2 1 7.8 14.2 1.3 1 0 0 1 1 1 0 Utp14 protein Dapper PF15268.6 GBG70460.1 - 2.3 7.0 8.3 2.8 6.7 8.3 1.1 1 0 0 1 1 1 0 Dapper NPR3 PF03666.13 GBG70460.1 - 9.4 4.9 15.4 14 4.3 15.4 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RVT_1 PF00078.27 GBG70461.1 - 2.7e-36 125.2 0.0 3.9e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70461.1 - 7.6e-30 102.9 0.0 1.4e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70461.1 - 5.3e-24 84.5 0.0 1.2e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4392 PF14336.6 GBG70461.1 - 0.055 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) PC-Esterase PF13839.6 GBG70462.1 - 4.4e-56 190.7 0.1 3.7e-41 141.7 0.0 3.7 3 0 0 3 3 3 3 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p RVT_1 PF00078.27 GBG70462.1 - 6.1e-29 101.1 0.0 1.1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PMR5N PF14416.6 GBG70462.1 - 0.036 14.4 1.4 0.094 13.0 1.4 1.7 1 0 0 1 1 1 0 PMR5 N terminal Domain CDC45 PF02724.14 GBG70462.1 - 2 6.6 16.4 4.4 5.5 16.4 1.5 1 0 0 1 1 1 0 CDC45-like protein NfeD PF01957.18 GBG70464.1 - 0.0053 17.1 4.9 0.034 14.5 0.6 2.1 1 1 1 2 2 2 2 NfeD-like C-terminal, partner-binding Myb_DNA-bind_4 PF13837.6 GBG70465.1 - 9.4e-08 32.3 0.3 9.4e-08 32.3 0.3 2.4 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70465.1 - 0.11 12.9 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like NAM-associated PF14303.6 GBG70465.1 - 0.41 11.4 4.9 0.81 10.4 4.1 2.0 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain AAA PF00004.29 GBG70466.1 - 4.1e-42 143.7 0.0 8e-42 142.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG70466.1 - 1.8e-12 46.9 0.1 4.4e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GBG70466.1 - 4.3e-10 39.4 0.3 1.2e-09 38.0 0.1 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 GBG70466.1 - 4.1e-07 30.5 0.0 0.00027 21.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 GBG70466.1 - 2.1e-06 28.0 0.0 2.3e-05 24.6 0.0 2.4 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GBG70466.1 - 3.3e-06 26.9 0.0 9.1e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GBG70466.1 - 5.6e-06 26.4 0.0 0.00012 22.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GBG70466.1 - 0.00019 21.7 0.0 0.022 15.0 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 GBG70466.1 - 0.00097 18.4 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 GBG70466.1 - 0.0013 18.2 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 GBG70466.1 - 0.0016 19.0 1.0 0.01 16.4 0.0 2.5 3 1 0 3 3 2 1 AAA domain TIP49 PF06068.13 GBG70466.1 - 0.0029 16.9 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 GBG70466.1 - 0.0033 17.1 0.0 0.011 15.4 0.0 1.9 1 1 1 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 GBG70466.1 - 0.0039 16.9 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 GBG70466.1 - 0.0045 16.4 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GBG70466.1 - 0.0046 17.3 0.0 0.0097 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 GBG70466.1 - 0.0074 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 GBG70466.1 - 0.011 15.4 0.4 0.03 14.0 0.1 1.9 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain AAA_14 PF13173.6 GBG70466.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 GBG70466.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 GBG70466.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GBG70466.1 - 0.016 15.3 0.0 0.043 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 GBG70466.1 - 0.024 14.5 0.1 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GBG70466.1 - 0.026 14.2 0.0 0.083 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 GBG70466.1 - 0.032 14.2 0.0 0.093 12.6 0.0 1.8 2 0 0 2 2 1 0 NACHT domain AAA_28 PF13521.6 GBG70466.1 - 0.036 14.3 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 GBG70466.1 - 0.048 13.0 0.1 0.19 11.0 0.0 2.0 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 GBG70466.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GBG70466.1 - 0.073 13.0 0.0 0.29 11.0 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 GBG70466.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 GBG70466.1 - 0.1 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 GBG70466.1 - 0.15 11.6 0.2 0.38 10.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_13 PF13166.6 GBG70466.1 - 1.7 7.2 3.7 6.1 5.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain CDC50 PF03381.15 GBG70467.1 - 2.2e-69 234.1 0.0 2.9e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RVT_1 PF00078.27 GBG70469.1 - 3.3e-27 95.4 0.1 4.9e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70469.1 - 2.5e-12 46.7 0.0 9e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG70469.1 - 7e-07 29.8 0.0 1.4e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70469.1 - 1.5e-06 28.7 0.0 3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG70469.1 - 4.4e-06 26.5 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG70469.1 - 0.00028 20.7 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG70469.1 - 0.001 19.3 0.0 0.0036 17.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase SAB PF04382.13 GBG70470.1 - 0.038 14.1 0.4 0.11 12.6 0.4 1.8 1 0 0 1 1 1 0 SAB domain Histone_HNS PF00816.21 GBG70470.1 - 0.13 13.1 8.6 0.065 14.1 4.9 2.1 2 0 0 2 2 2 0 H-NS histone family RNR_Alpha PF17975.1 GBG70470.1 - 0.25 11.9 1.1 0.73 10.4 0.0 2.1 2 1 0 2 2 2 0 Ribonucleotide reductase alpha domain PIEZO PF15917.5 GBG70470.1 - 0.46 9.9 4.2 0.63 9.5 4.2 1.2 1 0 0 1 1 1 0 Piezo Baculo_PEP_C PF04513.12 GBG70470.1 - 0.51 10.4 3.9 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 GBG70470.1 - 0.84 10.0 11.7 0.44 10.9 1.5 3.4 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NifQ PF04891.12 GBG70470.1 - 2 8.8 7.0 3.9 7.8 6.8 1.7 1 1 0 1 1 1 0 NifQ Ax_dynein_light PF10211.9 GBG70470.1 - 3.3 7.6 12.7 5.6 6.9 0.3 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Mu-like_Pro PF10123.9 GBG70470.1 - 8.3 5.9 17.9 4.7 6.7 1.4 2.2 1 1 1 2 2 2 0 Mu-like prophage I protein SDA1 PF05285.12 GBG70471.1 - 0.0035 16.8 5.0 0.0035 16.8 5.0 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG70471.1 - 0.01 14.1 7.7 0.011 14.0 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG70471.1 - 0.099 12.9 12.7 0.17 12.2 12.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG70471.1 - 0.73 8.0 10.6 0.82 7.9 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Histone PF00125.24 GBG70472.1 - 1.6e-21 77.0 2.4 2.1e-21 76.7 2.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG70472.1 - 3.2e-05 24.1 0.1 3.2e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GBG70472.1 - 0.0012 19.3 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 GBG70472.1 - 0.0037 17.3 2.8 0.0045 17.1 2.8 1.1 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 GBG70472.1 - 0.013 15.1 0.2 1.8 8.2 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Hydant_A_N PF05378.13 GBG70472.1 - 0.054 13.2 0.2 0.078 12.7 0.2 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region NAD_binding_10 PF13460.6 GBG70473.1 - 3.5e-19 69.4 0.0 6.2e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GBG70473.1 - 8e-09 35.3 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GBG70473.1 - 1e-06 28.0 0.0 1.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 GBG70473.1 - 0.00075 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 GBG70473.1 - 0.022 13.9 0.0 0.052 12.6 0.0 1.7 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GBG70473.1 - 0.041 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 GBG70473.1 - 0.042 14.1 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.12 GBG70473.1 - 0.052 12.7 0.1 3.7 6.7 0.0 3.1 3 1 1 4 4 4 0 Male sterility protein Lysine_decarbox PF03641.14 GBG70473.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Possible lysine decarboxylase RT_RNaseH PF17917.1 GBG70474.1 - 2e-22 79.4 0.0 3.5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70474.1 - 2.8e-22 78.6 0.0 4.8e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG70474.1 - 2.8e-06 27.8 0.1 6.1e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG70474.1 - 1.9e-05 24.7 0.0 4.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG70474.1 - 0.00017 22.1 0.1 0.00041 20.9 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG70474.1 - 0.0073 16.1 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG70474.1 - 0.015 14.9 0.2 0.04 13.6 0.2 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG70474.1 - 0.077 13.1 1.9 0.15 12.2 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG70475.1 - 2.4e-12 46.8 0.0 8.6e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG70475.1 - 0.00011 22.8 0.0 0.00043 20.9 0.0 2.1 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70475.1 - 0.00055 20.4 0.0 0.0026 18.3 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG70475.1 - 0.0012 18.6 0.0 0.0039 17.0 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG70475.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG70475.1 - 0.0068 16.6 3.9 0.0085 16.3 0.1 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein YPEB PF14620.6 GBG70475.1 - 0.04 13.2 0.2 0.065 12.6 0.2 1.2 1 0 0 1 1 1 0 YpeB sporulation HIP1_clath_bdg PF16515.5 GBG70475.1 - 0.046 14.3 6.0 0.041 14.5 3.1 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Senescence_reg PF04520.13 GBG70475.1 - 0.053 14.4 1.1 0.19 12.6 1.1 1.9 2 0 0 2 2 1 0 Senescence regulator DUF4618 PF15397.6 GBG70475.1 - 0.068 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 GBG70475.1 - 0.22 12.0 2.3 2.9 8.4 0.1 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Scaffolding_pro PF11418.8 GBG70475.1 - 0.25 11.9 1.0 49 4.6 0.0 3.0 3 0 0 3 3 3 0 Phi29 scaffolding protein Lzipper-MIP1 PF14389.6 GBG70475.1 - 0.41 11.0 5.4 7.1 7.0 0.2 3.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 GBG70475.1 - 2.3 8.0 7.1 1.4 8.7 1.3 3.0 3 0 0 3 3 3 0 Septum formation initiator ATG16 PF08614.11 GBG70475.1 - 2.8 8.1 12.2 1.2 9.4 4.1 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Tyrosinase PF00264.20 GBG70476.1 - 3e-31 109.5 8.9 3.1e-16 60.3 1.2 2.2 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG70476.1 - 4.4e-12 45.6 0.1 9.1e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain DUF5543 PF17697.1 GBG70476.1 - 0.17 12.1 0.9 0.35 11.2 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5543) HCV_NS5a_C PF12941.7 GBG70476.1 - 9.4 6.0 8.6 27 4.5 3.5 2.5 3 0 0 3 3 3 0 HCV NS5a protein C-terminal region PhoLip_ATPase_C PF16212.5 GBG70477.1 - 1.5e-38 133.0 3.0 2.6e-38 132.2 3.0 1.3 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 GBG70477.1 - 3.4e-12 46.3 0.0 1.2e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GBG70477.1 - 2.7e-11 44.2 0.5 3.5e-07 30.7 0.5 3.0 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GBG70477.1 - 4.3e-09 36.2 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase PhoLip_ATPase_N PF16209.5 GBG70477.1 - 0.00016 21.3 0.2 0.0003 20.4 0.2 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase_3 PF08282.12 GBG70477.1 - 0.0012 18.7 0.0 0.018 14.8 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cas_DxTHG PF09455.10 GBG70477.1 - 0.17 11.4 1.1 0.3 10.6 1.1 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family DUF1682 PF07946.14 GBG70477.1 - 6.1 6.0 14.9 10 5.2 14.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) EIN3 PF04873.13 GBG70478.1 - 1.5e-122 407.8 7.3 2e-122 407.4 7.3 1.2 1 0 0 1 1 1 1 Ethylene insensitive 3 DUF2841 PF11001.8 GBG70478.1 - 4.6e-05 23.5 2.4 7.6e-05 22.8 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) Integrase_H2C2 PF17921.1 GBG70479.1 - 5e-08 32.9 0.0 1.2e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG70479.1 - 2.7e-05 23.8 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG70480.1 - 1.5e-19 70.3 0.0 2.9e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Defensin_2 PF01097.18 GBG70480.1 - 0.13 12.3 0.4 0.33 10.9 0.4 1.7 1 0 0 1 1 1 0 Arthropod defensin BUD22 PF09073.10 GBG70480.1 - 2.1 7.6 51.3 4.5 6.5 51.3 1.5 1 0 0 1 1 1 0 BUD22 CSD PF00313.22 GBG70482.1 - 9.4e-25 86.3 0.1 1.3e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 GBG70482.1 - 4.8e-17 61.2 13.5 2.2e-08 33.8 4.8 2.4 2 0 0 2 2 2 2 Zinc knuckle OB_RNB PF08206.11 GBG70482.1 - 0.00022 20.9 0.1 0.00039 20.0 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain zf-CCHC_2 PF13696.6 GBG70482.1 - 0.006 16.4 10.2 0.066 13.0 1.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 GBG70482.1 - 0.008 15.9 7.1 0.37 10.6 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 GBG70482.1 - 0.0085 15.8 5.8 0.37 10.5 0.4 2.4 1 1 1 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 GBG70482.1 - 0.016 15.1 7.4 0.78 9.8 0.5 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG70482.1 - 5 7.1 11.6 1.8 8.5 4.2 2.4 2 0 0 2 2 2 0 Zinc knuckle RRM_1 PF00076.22 GBG70483.1 - 6.8e-27 93.1 0.5 7.6e-11 41.7 0.0 4.1 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 GBG70483.1 - 1e-11 45.0 0.0 2e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 SPOC domain Na_H_Exchanger PF00999.21 GBG70484.1 - 1.7e-48 165.3 28.6 8.1e-29 100.6 13.2 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family RVT_1 PF00078.27 GBG70484.1 - 6.6e-25 87.9 1.2 1.3e-24 87.0 0.0 2.1 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70484.1 - 3.8e-22 78.2 0.0 8.8e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70484.1 - 6.1e-22 77.9 0.0 1.5e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70484.1 - 3.1e-19 68.8 0.1 7.3e-19 67.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG70484.1 - 0.00025 21.6 0.0 0.00059 20.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70484.1 - 0.00054 20.6 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG70484.1 - 0.0043 17.3 2.3 0.0078 16.5 0.2 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG70484.1 - 0.0066 16.7 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG70484.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease UPF0242 PF06785.11 GBG70484.1 - 0.14 12.2 0.3 0.28 11.2 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RVP_2 PF08284.11 GBG70484.1 - 0.15 11.8 0.0 0.92 9.3 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease FAM176 PF14851.6 GBG70486.1 - 0.1 12.3 0.1 0.1 12.3 0.1 2.4 2 1 1 3 3 3 0 FAM176 family NOA36 PF06524.12 GBG70486.1 - 0.18 11.1 3.7 0.25 10.6 3.7 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3169 PF11368.8 GBG70486.1 - 2.8 7.4 9.2 8 5.9 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) DNA_pol_phi PF04931.13 GBG70486.1 - 4.2 5.4 5.9 5.9 4.9 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DNA_alkylation PF08713.11 GBG70487.1 - 3.2e-38 131.6 0.0 4.7e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 DNA alkylation repair enzyme BSP_II PF05432.11 GBG70491.1 - 0.19 11.4 90.7 0.23 11.1 15.2 5.8 5 0 0 5 5 5 0 Bone sialoprotein II (BSP-II) Asp_protease_2 PF13650.6 GBG70493.1 - 4.9e-08 33.5 0.0 9.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG70493.1 - 9.2e-08 31.9 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG70493.1 - 3.4e-07 30.7 0.0 6.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG70493.1 - 3.6e-05 23.9 1.0 7.4e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG70493.1 - 0.00025 20.8 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG70493.1 - 0.0038 17.1 0.0 0.0092 15.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Merozoite_SPAM PF07133.11 GBG70493.1 - 1 9.3 17.0 1.7 8.6 17.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RRN3 PF05327.11 GBG70493.1 - 7.4 5.0 6.6 12 4.3 6.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PFK PF00365.20 GBG70494.1 - 9.5e-35 120.3 0.0 1.2e-33 116.7 0.0 2.0 1 1 0 1 1 1 1 Phosphofructokinase RRM_1 PF00076.22 GBG70495.1 - 4.1e-17 61.8 0.0 6.9e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GBG70495.1 - 3e-05 24.0 0.0 6.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 GBG70495.1 - 0.0066 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sporozoite_P67 PF05642.11 GBG70495.1 - 0.028 12.5 5.2 0.032 12.4 5.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nup35_RRM_2 PF14605.6 GBG70495.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Myb_DNA-binding PF00249.31 GBG70498.1 - 1.4e-26 92.4 11.7 3.8e-07 30.2 0.1 5.2 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG70498.1 - 9.6e-21 73.8 7.7 5.4e-05 23.4 0.1 5.2 4 1 1 5 5 5 4 Myb-like DNA-binding domain CHDCT2 PF08074.11 GBG70498.1 - 0.00086 19.5 0.1 8.1 6.6 0.0 4.1 4 0 0 4 4 4 1 CHDCT2 (NUC038) domain SLIDE PF09111.10 GBG70498.1 - 0.0032 17.5 0.0 0.88 9.6 0.0 3.6 4 0 0 4 4 4 1 SLIDE Myb_DNA-bind_5 PF13873.6 GBG70498.1 - 3.1 7.9 16.3 11 6.2 0.5 4.8 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG70499.1 - 1.1e-26 92.7 11.7 3.6e-07 30.3 0.1 5.1 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG70499.1 - 7.2e-21 74.2 7.7 5.1e-05 23.4 0.1 5.2 4 1 1 5 5 5 4 Myb-like DNA-binding domain CHDCT2 PF08074.11 GBG70499.1 - 0.00068 19.8 0.1 7.7 6.7 0.0 4.1 4 0 0 4 4 4 1 CHDCT2 (NUC038) domain SLIDE PF09111.10 GBG70499.1 - 0.0026 17.7 0.0 0.83 9.7 0.0 3.6 4 0 0 4 4 4 1 SLIDE Myb_DNA-bind_5 PF13873.6 GBG70499.1 - 2.3 8.3 16.3 11 6.2 0.5 4.9 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain gag-asp_proteas PF13975.6 GBG70500.1 - 4.5e-10 39.9 0.0 1.2e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70500.1 - 1.9e-07 31.6 0.0 3.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG70500.1 - 4.3e-07 29.7 0.0 7.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG70500.1 - 5.9e-06 26.1 0.1 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG70500.1 - 0.00013 22.2 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Spc7 PF08317.11 GBG70501.1 - 0.29 10.0 4.2 0.46 9.3 4.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Chorion_2 PF03964.15 GBG70501.1 - 1.3 9.9 9.9 4.9 8.0 0.8 3.6 3 0 0 3 3 3 0 Chorion family 2 Macro PF01661.21 GBG70502.1 - 2e-26 92.4 0.1 2e-26 92.4 0.1 1.7 2 0 0 2 2 2 1 Macro domain CRAL_TRIO_2 PF13716.6 GBG70502.1 - 4.1e-26 91.8 0.7 1.5e-25 90.0 0.3 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CesT PF05932.13 GBG70502.1 - 0.16 12.1 0.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family CRAL_TRIO PF00650.20 GBG70502.1 - 0.18 11.5 0.5 0.54 10.0 0.5 1.8 1 1 0 1 1 1 0 CRAL/TRIO domain TPR_1 PF00515.28 GBG70503.1 - 2.5e-50 166.3 15.0 9.4e-07 28.4 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 GBG70503.1 - 8.9e-42 137.9 10.6 6.8e-05 22.7 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat STI1 PF17830.1 GBG70503.1 - 8.1e-39 131.4 14.6 2.7e-21 75.2 0.6 2.6 2 0 0 2 2 2 2 STI1 domain TPR_11 PF13414.6 GBG70503.1 - 1e-33 114.7 13.5 1.8e-07 30.7 0.0 7.2 4 2 3 7 7 7 6 TPR repeat TPR_8 PF13181.6 GBG70503.1 - 8.4e-25 84.9 10.5 0.0019 18.3 0.0 7.8 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 GBG70503.1 - 1.6e-20 73.4 6.1 6e-06 26.8 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 GBG70503.1 - 7.3e-19 67.8 1.0 0.0045 17.2 0.0 6.6 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 GBG70503.1 - 8.4e-18 64.6 4.3 0.014 15.9 0.0 5.7 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 GBG70503.1 - 2.8e-15 55.7 0.5 0.0032 18.2 0.1 7.0 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 GBG70503.1 - 1.3e-14 53.5 2.0 0.0077 16.5 0.0 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG70503.1 - 1.1e-10 41.5 0.0 0.0051 16.9 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG70503.1 - 1.6e-10 40.3 6.3 0.073 13.1 0.0 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 GBG70503.1 - 1.7e-06 27.7 3.6 3.1 7.8 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GBG70503.1 - 8.6e-05 22.5 0.9 19 5.4 0.1 5.4 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 GBG70503.1 - 0.00046 20.4 7.1 0.83 9.9 0.1 4.4 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 GBG70503.1 - 0.00056 20.2 0.4 11 6.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5113 PF17140.4 GBG70503.1 - 0.00073 19.4 2.3 7.5 6.3 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5113) SHNi-TPR PF10516.9 GBG70503.1 - 0.001 18.4 0.3 13 5.3 0.0 5.1 5 1 0 5 5 5 0 SHNi-TPR MIT PF04212.18 GBG70503.1 - 0.0016 18.4 7.7 11 6.2 0.1 5.9 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain Trypan_PARP PF05887.11 GBG70503.1 - 0.0032 17.5 10.0 0.0032 17.5 10.0 1.9 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) TPR_6 PF13174.6 GBG70503.1 - 0.0055 17.3 8.4 28 5.6 0.1 6.7 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 GBG70503.1 - 0.01 15.1 0.8 12 5.0 0.1 3.9 2 2 1 4 4 4 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 GBG70503.1 - 0.038 14.1 1.9 12 6.0 0.1 4.1 5 0 0 5 5 3 0 Exonuclease VII small subunit SPESP1 PF15754.5 GBG70503.1 - 0.038 13.2 5.1 0.074 12.2 5.1 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Uteroglobin PF01099.17 GBG70503.1 - 0.12 12.7 0.5 0.69 10.3 0.1 2.4 2 0 0 2 2 2 0 Uteroglobin family DUF3856 PF12968.7 GBG70503.1 - 0.26 11.3 6.9 45 4.1 0.0 5.1 4 2 1 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 GBG70503.1 - 0.33 11.0 9.8 0.92 9.6 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Nefa_Nip30_N PF10187.9 GBG70503.1 - 0.48 10.8 7.0 0.087 13.2 2.9 1.9 2 0 0 2 2 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Myb_DNA-bind_4 PF13837.6 GBG70506.1 - 4.2e-08 33.5 1.2 4.6e-07 30.1 0.3 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain CobT PF06213.12 GBG70507.1 - 0.3 10.5 23.7 0.38 10.1 23.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 GBG70507.1 - 1 8.7 30.9 1.2 8.5 30.9 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG70507.1 - 3.2 5.8 30.0 4.2 5.4 30.0 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG70507.1 - 3.6 6.8 32.3 4 6.7 32.3 1.0 1 0 0 1 1 1 0 BUD22 DDE_Tnp_4 PF13359.6 GBG70509.1 - 2e-25 89.3 0.0 4.5e-25 88.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70509.1 - 1e-09 38.3 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG70510.1 - 5e-10 39.6 0.5 5e-10 39.6 0.5 2.3 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70510.1 - 0.064 13.6 0.3 0.14 12.4 0.3 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4400 PF14348.6 GBG70510.1 - 0.18 11.3 1.6 0.31 10.5 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Ferlin_C PF16165.5 GBG70511.1 - 0.28 11.1 5.2 0.57 10.1 5.2 1.6 1 0 0 1 1 1 0 Ferlin C-terminus Sec62 PF03839.16 GBG70511.1 - 5.2 6.5 9.4 7.2 6.0 9.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Ricin_B_lectin PF00652.22 GBG70512.1 - 6.2e-08 32.9 2.6 1.6e-05 25.2 0.4 2.4 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 GBG70512.1 - 0.0056 17.4 0.4 0.022 15.5 0.1 2.0 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CDC27 PF09507.10 GBG70513.1 - 0.015 14.7 0.2 0.015 14.7 0.2 2.7 3 1 0 3 3 3 0 DNA polymerase subunit Cdc27 Dimer_Tnp_hAT PF05699.14 GBG70513.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region CDC45 PF02724.14 GBG70513.1 - 0.21 9.8 8.2 0.45 8.8 8.2 1.4 1 0 0 1 1 1 0 CDC45-like protein DDE_Tnp_4 PF13359.6 GBG70514.1 - 3.5e-21 75.5 0.0 5e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70514.1 - 2.7e-13 50.0 0.0 1.2e-12 47.9 0.0 1.8 1 1 0 1 1 1 1 Plant transposon protein zf-CHC2 PF01807.20 GBG70514.1 - 0.21 11.4 1.2 14 5.6 0.4 2.3 2 0 0 2 2 2 0 CHC2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG70515.1 - 8.8e-11 42.1 1.2 8.8e-11 42.1 1.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF4407 PF14362.6 GBG70516.1 - 4.6 6.5 17.2 6.3 6.1 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Metallophos PF00149.28 GBG70517.1 - 5.6e-11 43.3 2.8 2.8e-09 37.8 2.8 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4604 PF15377.6 GBG70517.1 - 0.012 16.1 1.4 0.012 16.1 1.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) Ribosomal_60s PF00428.19 GBG70517.1 - 0.029 15.0 28.3 0.58 10.8 5.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein RPA43_OB PF17875.1 GBG70517.1 - 0.15 12.7 5.0 4 8.1 0.9 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I RPN2_C PF18004.1 GBG70517.1 - 0.49 10.3 14.5 1.2 9.0 2.9 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_polI_A34 PF08208.11 GBG70517.1 - 0.5 10.4 19.9 0.056 13.5 5.2 2.5 3 0 0 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 GOLD_2 PF13897.6 GBG70517.1 - 0.71 10.4 9.6 0.84 10.1 0.0 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Tim54 PF11711.8 GBG70517.1 - 1.2 7.8 16.0 0.067 12.0 0.6 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 GBG70517.1 - 1.2 9.3 8.9 1.6 8.9 0.5 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Radial_spoke PF04712.12 GBG70517.1 - 1.5 7.7 19.1 1.7 7.5 1.1 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein SpoIIP PF07454.11 GBG70517.1 - 2.2 7.6 7.9 7 6.0 0.6 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) FAM176 PF14851.6 GBG70517.1 - 3.9 7.1 14.7 5 6.8 0.2 2.6 2 0 0 2 2 2 0 FAM176 family RR_TM4-6 PF06459.12 GBG70517.1 - 4.2 7.1 12.7 1.9 8.3 1.0 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 U1snRNP70_N PF12220.8 GBG70517.1 - 4.9 7.9 21.9 3.1 8.5 3.0 3.3 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TFB6 PF17110.5 GBG70517.1 - 5.5 6.7 8.7 8.5 6.1 0.1 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Presenilin PF01080.17 GBG70517.1 - 5.8 5.6 8.1 0.14 10.9 1.4 1.6 2 1 0 2 2 2 0 Presenilin DUF3682 PF12446.8 GBG70517.1 - 6.4 7.3 27.6 7.1 7.1 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) AIF_C PF14721.6 GBG70517.1 - 6.6 7.1 7.4 2.8 8.3 0.3 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DDE_Tnp_4 PF13359.6 GBG70518.1 - 5.7e-27 94.3 0.0 9.5e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70518.1 - 1.2e-13 51.1 0.0 2.2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70518.1 - 0.022 14.4 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG70519.1 - 3.8e-11 43.2 1.0 3.8e-11 43.2 1.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70519.1 - 0.0025 18.1 0.1 0.0075 16.6 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG70519.1 - 2.2 8.4 4.7 1.1 9.3 1.7 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG70520.1 - 6.9e-28 96.6 0.0 1.3e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70520.1 - 9.2e-26 90.2 0.0 2.2e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70520.1 - 9.7e-20 70.4 0.4 3.1e-19 68.8 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG70520.1 - 1.7e-09 37.5 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70524.1 - 1.7e-28 98.6 0.0 7.5e-28 96.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70524.1 - 2.2e-25 89.0 0.0 7.4e-25 87.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70524.1 - 5.3e-25 88.2 0.1 8.5e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG70524.1 - 0.006 16.1 13.5 0.011 15.2 13.5 1.3 1 0 0 1 1 1 1 SDA1 Na_trans_assoc PF06512.13 GBG70524.1 - 1.1 9.5 14.6 2.2 8.5 14.6 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 GBG70524.1 - 1.2 8.5 18.8 2 7.7 18.8 1.3 1 0 0 1 1 1 0 BUD22 Mo25 PF08569.11 GBG70526.1 - 1.4e-122 409.1 2.9 1.6e-122 409.0 2.9 1.0 1 0 0 1 1 1 1 Mo25-like HEAT PF02985.22 GBG70526.1 - 0.012 15.8 0.0 0.38 11.1 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 GBG70526.1 - 0.068 13.6 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats Clat_adaptor_s PF01217.20 GBG70527.1 - 6.6e-48 162.3 0.9 7.7e-48 162.0 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NPAT_C PF15712.5 GBG70528.1 - 1.4 7.5 10.5 2.1 6.9 10.5 1.2 1 0 0 1 1 1 0 NPAT C terminus Vfa1 PF08432.10 GBG70528.1 - 5.5 7.3 14.5 10 6.4 14.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PA26 PF04636.13 GBG70528.1 - 8.3 5.2 10.9 12 4.7 10.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RT_RNaseH_2 PF17919.1 GBG70529.1 - 5.1e-19 68.2 0.0 8.9e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70529.1 - 2.9e-10 40.0 0.1 4e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70529.1 - 3.1e-10 40.3 0.0 7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG70529.1 - 0.086 11.9 0.0 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG70531.1 - 3.5e-37 126.5 0.0 1.7e-19 69.7 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70531.1 - 4.9e-37 127.6 0.2 8.4e-24 84.3 0.1 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70531.1 - 1.9e-24 85.9 0.0 1.8e-11 44.3 0.0 4.0 3 1 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG70531.1 - 0.0002 21.5 0.7 0.012 15.9 0.0 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein APG17 PF04108.12 GBG70531.1 - 0.0015 17.7 1.7 11 4.9 0.0 3.8 3 1 0 3 3 3 2 Autophagy protein Apg17 TolA_bind_tri PF16331.5 GBG70531.1 - 0.028 14.5 3.7 0.07 13.2 3.7 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation CDH1_2_SANT_HL1 PF18375.1 GBG70531.1 - 0.19 12.4 0.1 6.7 7.5 0.0 2.9 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 SlyX PF04102.12 GBG70531.1 - 0.78 10.4 5.2 3.9 8.2 1.3 2.9 2 0 0 2 2 2 0 SlyX Pkinase_Tyr PF07714.17 GBG70533.1 - 2.6e-31 108.9 0.0 5.5e-31 107.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 GBG70533.1 - 3.2e-31 108.6 0.0 8.1e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG70533.1 - 5.5e-31 107.9 0.0 9.2e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 GBG70533.1 - 7.7e-08 32.0 12.5 5.4e-05 22.9 1.7 3.6 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GBG70533.1 - 1.2e-05 25.6 13.5 0.00075 19.8 0.8 3.8 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG70533.1 - 0.00093 19.4 6.3 16 6.5 0.3 5.6 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 GBG70533.1 - 0.0045 16.9 5.7 10 6.5 0.1 4.8 4 0 0 4 4 4 1 Leucine Rich repeat TMEM154 PF15102.6 GBG70534.1 - 0.021 14.7 0.3 0.11 12.4 0.3 2.3 1 0 0 1 1 1 0 TMEM154 protein family Mlo PF03094.15 GBG70535.1 - 1.1e-121 406.6 2.7 1.4e-121 406.3 2.7 1.0 1 0 0 1 1 1 1 Mlo family DDE_Tnp_4 PF13359.6 GBG70536.1 - 1.4e-21 76.8 0.0 1.3e-19 70.4 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70536.1 - 2.8e-08 33.6 0.0 5.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70536.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Transposase DDE domain ORC2 PF04084.14 GBG70537.1 - 1.9e-94 316.3 0.0 2.2e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 gag-asp_proteas PF13975.6 GBG70538.1 - 0.024 15.2 0.0 0.065 13.8 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG70538.1 - 0.032 14.0 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease GCK PF07802.11 GBG70538.1 - 0.042 14.3 0.4 0.13 12.7 0.4 1.8 1 0 0 1 1 1 0 GCK domain Seryl_tRNA_N PF02403.22 GBG70538.1 - 0.058 13.6 5.6 0.28 11.4 0.0 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 GBG70539.1 - 5.3e-62 209.6 0.0 7.7e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70539.1 - 2.1e-31 109.1 0.0 3.1e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GBG70539.1 - 0.0013 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Goodbye PF17109.5 GBG70540.1 - 0.096 13.1 1.7 0.41 11.1 0.0 2.2 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain DUF4072 PF13284.6 GBG70540.1 - 0.61 10.6 2.9 3.3 8.2 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) Dimer_Tnp_hAT PF05699.14 GBG70541.1 - 2e-07 30.7 0.0 5.1e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG70542.1 - 8e-35 120.4 0.0 8e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70542.1 - 2.4e-29 101.3 0.0 2.4e-29 101.3 0.0 3.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70542.1 - 4.9e-29 100.7 0.0 4.9e-29 100.7 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70542.1 - 5e-14 52.2 0.1 1.1e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG70542.1 - 3.6e-06 26.8 0.0 6.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70542.1 - 6e-06 26.8 0.5 8.2e-05 23.2 0.0 3.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70542.1 - 0.0043 17.6 0.0 0.0043 17.6 0.0 4.0 4 1 2 6 6 6 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG70542.1 - 0.03 14.1 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Myb_DNA-binding PF00249.31 GBG70542.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain RVT_1 PF00078.27 GBG70543.1 - 8e-35 120.4 0.0 8e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70543.1 - 2.4e-29 101.3 0.0 2.4e-29 101.3 0.0 3.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70543.1 - 4.9e-29 100.7 0.0 4.9e-29 100.7 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70543.1 - 5e-14 52.2 0.1 1.1e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG70543.1 - 3.6e-06 26.8 0.0 6.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70543.1 - 6e-06 26.8 0.5 8.2e-05 23.2 0.0 3.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70543.1 - 0.0043 17.6 0.0 0.0043 17.6 0.0 4.0 4 1 2 6 6 6 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG70543.1 - 0.03 14.1 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Myb_DNA-binding PF00249.31 GBG70543.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain RVT_1 PF00078.27 GBG70544.1 - 7.9e-35 120.4 0.0 7.9e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70544.1 - 2.4e-29 101.3 0.0 2.4e-29 101.3 0.0 3.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70544.1 - 4.9e-29 100.7 0.0 4.9e-29 100.7 0.0 2.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70544.1 - 4.9e-14 52.2 0.1 1.1e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG70544.1 - 3.5e-06 26.8 0.0 6.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70544.1 - 5.8e-06 26.9 0.5 8.1e-05 23.2 0.0 3.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70544.1 - 0.0042 17.6 0.0 0.0042 17.6 0.0 4.0 4 1 2 6 6 6 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG70544.1 - 0.03 14.1 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Myb_DNA-binding PF00249.31 GBG70544.1 - 0.05 13.8 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain BAF1_ABF1 PF04684.13 GBG70546.1 - 0.023 13.8 13.6 0.031 13.4 13.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fungus-induced PF10917.8 GBG70546.1 - 4.3 7.7 6.3 3.2 8.2 1.8 2.5 2 0 0 2 2 2 0 Fungus-induced protein BUD22 PF09073.10 GBG70546.1 - 4.4 6.5 8.6 6.3 6.0 8.6 1.3 1 0 0 1 1 1 0 BUD22 Orf78 PF06024.12 GBG70546.1 - 4.9 7.5 13.2 3.7 7.9 2.2 2.3 2 0 0 2 2 2 0 Orf78 (ac78) WD40_alt PF14077.6 GBG70547.1 - 1.5 8.7 4.8 1.9 8.4 0.5 2.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif RT_RNaseH PF17917.1 GBG70548.1 - 6.9e-28 97.0 0.0 1.5e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70548.1 - 3.3e-27 94.4 0.0 1.7e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70548.1 - 4e-26 91.9 0.1 6.8e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG70548.1 - 1.4e-12 47.3 0.0 2.6e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HSA PF07529.13 GBG70549.1 - 2.8e-08 34.0 0.3 2.8e-08 34.0 0.3 4.0 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.6 GBG70549.1 - 0.034 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG70550.1 - 2.1e-08 34.4 1.8 3.9e-08 33.6 1.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG70550.1 - 0.0045 17.1 4.7 0.012 15.8 1.4 2.5 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG70550.1 - 0.0079 16.2 0.5 0.019 15.1 0.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG70550.1 - 0.069 13.4 0.4 0.23 11.7 0.0 2.1 2 1 0 2 2 2 0 Myb-like DNA-binding domain zf-CHCC PF10276.9 GBG70553.1 - 3.4e-13 49.4 0.2 1.5e-12 47.3 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger domain zf_C2H2_6 PF18450.1 GBG70553.1 - 0.0098 15.6 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Zinc Finger domain Rif1_N PF12231.8 GBG70554.1 - 8.4e-12 44.8 0.2 1.9e-11 43.6 0.1 1.6 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Fer2_4 PF13510.6 GBG70554.1 - 0.051 13.6 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Chorion_3 PF05387.11 GBG70555.1 - 1.9 8.1 3.8 3.8 7.1 0.4 1.9 1 1 1 2 2 2 0 Chorion family 3 Myb_DNA-bind_4 PF13837.6 GBG70556.1 - 6.3e-10 39.3 2.4 1.2e-09 38.5 1.4 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70556.1 - 0.061 13.6 0.4 0.14 12.4 0.4 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RT_RNaseH PF17917.1 GBG70558.1 - 2e-18 66.6 0.7 6.4e-18 65.0 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70558.1 - 6e-11 42.3 0.1 1.2e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rad51 PF08423.11 GBG70559.1 - 2e-06 27.3 0.0 2.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GBG70559.1 - 0.0043 16.7 0.0 0.0057 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GBG70559.1 - 0.0079 16.7 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 GBG70559.1 - 0.0084 16.3 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GBG70559.1 - 0.025 14.5 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RecA PF00154.21 GBG70559.1 - 0.031 13.7 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Sec8_exocyst PF04048.14 GBG70559.1 - 0.052 13.4 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain AAA_35 PF14516.6 GBG70559.1 - 0.065 12.1 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 GBG70559.1 - 0.11 11.8 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.6 GBG70559.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 GBG70559.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 GBG70559.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RT_RNaseH_2 PF17919.1 GBG70560.1 - 2.5e-29 101.2 0.0 8.7e-29 99.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70560.1 - 1.2e-27 96.2 0.0 2.6e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70560.1 - 1.2e-17 64.2 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG70560.1 - 0.17 11.8 1.4 4.1 7.4 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) Na_trans_assoc PF06512.13 GBG70560.1 - 1.5 9.1 15.5 2.6 8.3 15.5 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG70560.1 - 1.8 7.9 33.2 3.1 7.1 33.2 1.2 1 0 0 1 1 1 0 SDA1 Glyco_hydro_77 PF02446.17 GBG70561.1 - 3.2e-146 487.9 0.7 4.2e-146 487.5 0.7 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 GBG70561.1 - 3.5e-14 52.5 0.0 1.4e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Starch binding domain NTP_transf_2 PF01909.23 GBG70562.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 Nucleotidyltransferase domain Citrate_bind PF16114.5 GBG70563.1 - 1e-78 262.9 0.0 1.6e-78 262.3 0.0 1.3 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 GBG70563.1 - 1.1e-15 57.7 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain CobN-Mg_chel PF02514.16 GBG70565.1 - 4.6e-205 683.7 0.5 3.7e-163 544.9 0.6 3.1 3 0 0 3 3 3 3 CobN/Magnesium Chelatase DUF3479 PF11965.8 GBG70565.1 - 1.5e-49 168.2 0.0 3.7e-49 166.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) BLOC1_2 PF10046.9 GBG70565.1 - 0.74 10.1 2.3 2.4 8.5 0.2 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C2H2 PF00096.26 GBG70567.1 - 1.4e-20 72.5 46.6 0.00015 22.1 0.5 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GBG70567.1 - 1.1e-13 50.7 42.8 0.021 15.6 0.4 7.7 7 0 0 7 7 7 5 C2H2-type zinc finger zf-Di19 PF05605.12 GBG70567.1 - 1.8e-08 34.5 26.8 0.002 18.4 1.2 4.5 4 0 0 4 4 4 4 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 GBG70567.1 - 8.5e-07 29.2 18.6 1.9 9.0 0.2 7.5 8 0 0 8 8 8 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 GBG70567.1 - 1.8e-05 24.9 48.7 2.7e-05 24.4 0.5 8.0 8 0 0 8 8 8 3 Zinc-finger double domain zf-C2H2_aberr PF17017.5 GBG70567.1 - 3.7e-05 24.0 11.9 0.007 16.5 3.1 3.6 3 0 0 3 3 3 2 Aberrant zinc-finger FOXP-CC PF16159.5 GBG70567.1 - 0.00015 22.3 17.5 0.17 12.5 0.1 5.5 2 2 3 5 5 5 2 FOXP coiled-coil domain CNDH2_C PF16858.5 GBG70567.1 - 0.0082 16.1 9.0 0.0082 16.1 9.0 4.0 3 1 0 3 3 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CENP-B_dimeris PF09026.10 GBG70567.1 - 0.0095 16.3 4.8 0.0095 16.3 4.8 5.0 4 1 1 5 5 5 1 Centromere protein B dimerisation domain GAGA PF09237.11 GBG70567.1 - 0.025 14.4 10.0 0.4 10.5 0.6 3.8 3 1 0 3 3 3 0 GAGA factor zf-C2H2_jaz PF12171.8 GBG70567.1 - 0.2 12.0 21.2 2.5 8.5 0.0 6.2 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 GBG70567.1 - 0.22 11.3 0.0 0.22 11.3 0.0 6.4 8 0 0 8 8 8 0 C2H2-type zinc-finger domain Integrase_H2C2 PF17921.1 GBG70568.1 - 1e-12 48.0 0.1 2.7e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG70568.1 - 0.00017 21.2 0.0 0.00038 20.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prominin PF05478.11 GBG70568.1 - 0.009 14.0 0.4 0.014 13.4 0.4 1.2 1 0 0 1 1 1 1 Prominin GIT_CC PF16559.5 GBG70568.1 - 4.5 7.2 7.0 9.8 6.1 3.4 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DDE_Tnp_4 PF13359.6 GBG70569.1 - 6e-33 113.8 0.0 2.9e-30 105.0 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70569.1 - 3.9e-18 65.8 0.0 7.7e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70569.1 - 0.0025 17.5 0.2 7.2 6.2 0.0 3.1 3 0 0 3 3 3 2 Transposase DDE domain Asparaginase PF00710.20 GBG70570.1 - 5.4e-42 143.5 0.0 3.3e-40 137.7 0.0 2.7 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 GBG70570.1 - 4e-06 27.0 0.0 2.2e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain T3SSipB PF16535.5 GBG70572.1 - 0.017 15.6 0.1 0.025 15.1 0.1 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB GAS PF13851.6 GBG70572.1 - 0.029 13.7 1.4 0.29 10.5 0.3 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding COG6 PF06419.11 GBG70572.1 - 0.1 10.8 1.4 0.35 9.0 0.2 1.8 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 CENP-H PF05837.12 GBG70572.1 - 0.14 12.6 2.1 0.28 11.6 2.1 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) OEP PF02321.18 GBG70572.1 - 0.37 10.6 3.1 0.56 10.0 3.1 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DHR10 PF18595.1 GBG70572.1 - 0.43 10.6 10.6 0.41 10.7 1.5 2.6 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain KELK PF15796.5 GBG70572.1 - 0.45 11.0 5.1 0.49 10.9 4.0 1.6 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APG6_N PF17675.1 GBG70572.1 - 0.95 10.0 5.2 2.8 8.5 5.2 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region CorA PF01544.18 GBG70572.1 - 9.1 5.5 11.3 0.6 9.4 3.0 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Myb_DNA-bind_4 PF13837.6 GBG70573.1 - 4.4e-09 36.6 4.3 9.9e-09 35.5 4.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Lin-8 PF03353.15 GBG70574.1 - 0.39 10.2 16.9 0.56 9.7 16.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 GBG70574.1 - 2.7 7.2 27.4 3.8 6.7 27.4 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG70574.1 - 8.3 5.7 29.1 11 5.3 29.1 1.1 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG70576.1 - 1e-27 97.1 0.1 1.4e-27 96.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG70578.1 - 1.2e-27 96.5 0.0 4e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70578.1 - 4.5e-15 55.8 0.0 6.8e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70578.1 - 7.6e-05 22.4 0.6 0.00077 19.2 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG70579.1 - 4.4e-08 33.4 2.0 4.4e-08 33.4 2.0 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG70579.1 - 0.00055 20.1 0.3 0.0098 16.1 0.6 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70579.1 - 0.0049 17.2 2.3 0.02 15.2 0.9 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG70579.1 - 0.016 15.3 0.8 0.031 14.3 0.8 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RT_RNaseH PF17917.1 GBG70580.1 - 1.3e-29 102.5 0.0 7.3e-29 100.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70580.1 - 3.5e-29 100.8 0.0 1.6e-28 98.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70580.1 - 1.8e-11 44.0 0.1 3.7e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG70580.1 - 0.24 11.0 0.0 0.24 11.0 0.0 3.1 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase TssO PF17561.2 GBG70580.1 - 0.33 11.1 7.5 4.7 7.3 7.2 2.6 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF3138 PF11336.8 GBG70580.1 - 1.1 7.8 3.1 1.7 7.2 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DRY_EERY PF09750.9 GBG70580.1 - 2 8.7 0.0 2 8.7 0.0 3.2 3 0 0 3 3 3 0 Alternative splicing regulator Herpes_UL25 PF01499.16 GBG70580.1 - 5.5 5.4 7.0 27 3.1 7.1 1.9 2 0 0 2 2 2 0 Herpesvirus UL25 family Pre-PUA PF17832.1 GBG70581.1 - 6.8e-20 71.5 0.0 1.9e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Pre-PUA-like domain SUI1 PF01253.22 GBG70581.1 - 3.5e-19 69.1 1.4 9.2e-19 67.8 0.0 2.4 3 0 0 3 3 3 1 Translation initiation factor SUI1 PUA PF01472.20 GBG70581.1 - 6.8e-05 22.8 0.0 0.00033 20.6 0.0 2.2 2 0 0 2 2 2 1 PUA domain Nop14 PF04147.12 GBG70584.1 - 0.00056 18.3 22.6 0.00056 18.3 22.6 2.0 2 0 0 2 2 2 2 Nop14-like family DUF4246 PF14033.6 GBG70584.1 - 0.00066 18.9 5.6 0.069 12.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) SDA1 PF05285.12 GBG70584.1 - 0.0033 16.9 24.7 0.0033 16.9 24.7 2.2 2 0 0 2 2 2 1 SDA1 Vfa1 PF08432.10 GBG70584.1 - 0.0049 17.2 13.2 0.0049 17.2 13.2 2.4 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 Nop53 PF07767.11 GBG70584.1 - 0.0083 15.6 42.2 0.0083 15.6 42.2 2.4 3 0 0 3 3 3 2 Nop53 (60S ribosomal biogenesis) Sigma70_ner PF04546.13 GBG70584.1 - 0.018 14.9 16.9 0.018 14.9 16.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region BUD22 PF09073.10 GBG70584.1 - 0.026 13.9 54.3 0.041 13.2 54.3 1.3 1 0 0 1 1 1 0 BUD22 DUF2052 PF09747.9 GBG70584.1 - 2 8.5 66.0 3.4 7.7 33.3 2.2 1 1 1 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SpoIIIAH PF12685.7 GBG70584.1 - 4.4 7.1 31.2 0.1 12.4 6.8 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein UPF0176_N PF17773.1 GBG70585.1 - 1.5e-15 57.4 0.0 3.6e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain DDE_Tnp_4 PF13359.6 GBG70585.1 - 7.1e-11 42.0 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Rhodanese PF00581.20 GBG70585.1 - 2.5e-05 24.8 0.1 0.023 15.2 0.0 3.2 2 0 0 2 2 2 2 Rhodanese-like domain Rhodanese_C PF12368.8 GBG70585.1 - 0.0001 22.6 0.3 0.00025 21.4 0.3 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal DUF688 PF05097.12 GBG70585.1 - 0.0023 17.2 2.9 0.0023 17.2 2.9 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF688) Plant_tran PF04827.14 GBG70585.1 - 0.0033 17.1 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein zinc_ribbon_9 PF14369.6 GBG70585.1 - 0.093 13.0 3.2 0.27 11.5 3.2 1.8 1 0 0 1 1 1 0 zinc-ribbon DUF2052 PF09747.9 GBG70585.1 - 2.7 8.1 39.4 0.17 12.0 4.8 3.7 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) CCDC106 PF15794.5 GBG70586.1 - 7.5 6.2 8.4 17 5.1 8.4 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SPX PF03105.19 GBG70587.1 - 0.013 15.4 0.2 0.015 15.3 0.2 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 GBG70587.1 - 0.26 10.1 1.2 0.36 9.6 1.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PBP1_TM PF14812.6 GBG70587.1 - 0.96 9.9 5.2 1.9 8.9 5.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4551 PF15087.6 GBG70587.1 - 4.3 6.0 4.9 6.9 5.4 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MGC-24 PF05283.11 GBG70587.1 - 8.6 6.8 9.8 24 5.3 9.8 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HAUS4 PF14735.6 GBG70588.1 - 1.6e-50 172.1 1.2 1.7e-50 172.0 0.0 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 4 DUF3037 PF11236.8 GBG70588.1 - 0.17 12.4 0.9 36 4.8 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) DUF4477 PF14780.6 GBG70589.1 - 1.5e-15 57.4 2.3 2e-15 57.0 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) U-box PF04564.15 GBG70590.1 - 1.2e-08 35.0 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.6 GBG70590.1 - 2.9e-07 30.5 1.6 8.9e-07 29.0 1.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GBG70590.1 - 2.4e-06 27.3 0.7 5.4e-06 26.1 0.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG70590.1 - 3.1e-05 23.9 1.4 6.8e-05 22.8 1.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GBG70590.1 - 4.1e-05 23.8 1.8 0.00015 22.0 1.8 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG70590.1 - 8.9e-05 22.3 0.7 0.00028 20.7 0.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG70590.1 - 0.00056 19.7 1.5 0.0014 18.4 1.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Arm PF00514.23 GBG70590.1 - 0.0031 17.5 25.2 3.1 8.0 0.0 9.6 11 0 0 11 11 11 2 Armadillo/beta-catenin-like repeat zf-Nse PF11789.8 GBG70590.1 - 0.025 14.4 0.6 0.025 14.4 0.6 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RT_RNaseH_2 PF17919.1 GBG70591.1 - 3e-47 158.8 0.0 4.2e-29 100.5 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70591.1 - 3.5e-37 128.1 1.6 1.9e-31 109.3 0.1 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70591.1 - 1.9e-36 124.6 0.0 5.5e-29 100.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Pepdidase_M14_N PF18027.1 GBG70591.1 - 7.8e-13 48.7 0.3 2e-12 47.4 0.3 1.7 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Integrase_H2C2 PF17921.1 GBG70591.1 - 0.00076 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Jas PF16135.5 GBG70592.1 - 3.9e-25 87.8 9.4 9.5e-17 61.0 0.1 3.5 3 0 0 3 3 3 2 TPL-binding domain in jasmonate signalling PHD PF00628.29 GBG70592.1 - 2.8e-09 36.7 61.3 7e-07 29.0 7.1 4.6 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.6 GBG70592.1 - 0.00011 21.7 1.0 0.00011 21.7 1.0 4.7 5 0 0 5 5 5 2 PHD-finger zf-HC5HC2H PF13771.6 GBG70592.1 - 0.35 11.1 25.0 0.87 9.9 2.4 3.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain RT_RNaseH_2 PF17919.1 GBG70594.1 - 1.2e-24 86.2 0.0 2.7e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70594.1 - 4.2e-23 81.6 0.0 1.3e-22 80.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70594.1 - 9.4e-21 74.3 0.0 1.9e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG70594.1 - 2.2e-09 37.5 0.0 7.1e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG70594.1 - 0.00027 20.8 0.0 0.00053 19.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG70594.1 - 0.024 14.4 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Cytochrom_C PF00034.21 GBG70594.1 - 0.22 12.7 1.0 0.57 11.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c RasGAP_C PF03836.15 GBG70594.1 - 3.9 7.6 5.6 0.96 9.6 0.4 2.6 3 0 0 3 3 3 0 RasGAP C-terminus DUF659 PF04937.15 GBG70595.1 - 7.1e-33 113.6 0.0 9.8e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CDC45 PF02724.14 GBG70595.1 - 2.9 6.1 4.6 4.7 5.4 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 GBG70598.1 - 0.021 15.3 1.2 0.056 13.9 1.2 1.7 1 1 0 1 1 1 0 RNA polymerase III RPC4 Sigma70_ner PF04546.13 GBG70598.1 - 0.21 11.4 8.6 0.3 10.9 8.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PTPRCAP PF15713.5 GBG70598.1 - 3.8 7.8 17.9 6.5 7.0 17.9 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SspB PF04386.13 GBG70598.1 - 4 7.3 6.7 6 6.7 6.7 1.2 1 0 0 1 1 1 0 Stringent starvation protein B RRN3 PF05327.11 GBG70598.1 - 4.3 5.8 7.2 5.4 5.4 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 GBG70598.1 - 9.3 5.9 11.9 15 5.2 11.9 1.3 1 0 0 1 1 1 0 FAM176 family PLATZ PF04640.14 GBG70599.1 - 1.1e-26 93.3 1.4 1.1e-26 93.3 1.4 2.8 4 0 0 4 4 4 1 PLATZ transcription factor BUD22 PF09073.10 GBG70602.1 - 9 5.5 15.6 12 5.1 15.6 1.1 1 0 0 1 1 1 0 BUD22 RT_RNaseH_2 PF17919.1 GBG70604.1 - 6e-27 93.6 0.0 1.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70604.1 - 2.7e-25 89.2 0.0 5.3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70604.1 - 5.9e-25 87.6 0.0 1.1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG70604.1 - 2.5e-09 37.4 2.7 3.6e-09 36.9 1.0 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70604.1 - 0.035 14.4 0.5 0.11 12.8 0.5 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVP_2 PF08284.11 GBG70604.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Na_trans_assoc PF06512.13 GBG70604.1 - 0.48 10.7 27.2 0.21 11.9 12.2 3.4 3 0 0 3 3 3 0 Sodium ion transport-associated RNA_pol_Rpc4 PF05132.14 GBG70604.1 - 2.4 8.6 17.3 8 6.9 7.1 2.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 DDE_Tnp_4 PF13359.6 GBG70605.1 - 9.3e-20 70.9 0.0 1.5e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70605.1 - 9.5e-09 35.1 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70605.1 - 0.0008 19.1 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain HA2 PF04408.23 GBG70607.1 - 2.4e-26 92.1 0.0 2.4e-26 92.1 0.0 2.8 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GBG70607.1 - 1.9e-25 89.0 0.0 3.7e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GBG70607.1 - 2.7e-12 47.0 0.0 5.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 GBG70607.1 - 3.7e-08 33.6 0.1 7.1e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 GBG70607.1 - 2.4e-06 27.5 0.1 4.5e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GBG70607.1 - 0.00016 21.9 0.1 0.00041 20.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG70607.1 - 0.00056 19.7 0.1 0.0019 18.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GBG70607.1 - 0.0058 17.0 0.1 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GBG70607.1 - 0.0097 15.0 0.1 0.022 13.8 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 GBG70607.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 GBG70607.1 - 0.038 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 GBG70607.1 - 0.066 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 GBG70607.1 - 0.11 12.9 0.1 0.36 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 GBG70607.1 - 0.13 12.4 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 GBG70607.1 - 0.13 11.7 0.1 0.34 10.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Microtub_bd PF16796.5 GBG70607.1 - 0.21 11.5 0.2 3.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Microtubule binding PRIMA1 PF16101.5 GBG70607.1 - 6.9 6.7 12.5 18 5.4 12.5 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-TRAF PF02176.18 GBG70608.1 - 1.2e-13 51.5 6.9 4.7e-08 33.6 1.1 3.3 2 1 1 3 3 3 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 GBG70608.1 - 7.3e-10 39.2 19.9 2.3e-05 24.8 4.5 3.3 2 1 1 3 3 3 2 TRAF-like zinc-finger zf-C3HC4_2 PF13923.6 GBG70608.1 - 0.00062 19.6 11.4 0.00062 19.6 11.4 3.3 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf_C2HC_14 PF18574.1 GBG70608.1 - 0.0065 16.2 2.5 0.24 11.2 0.6 3.5 3 0 0 3 3 3 1 C2HC Zing finger domain zf-C3HC4_4 PF15227.6 GBG70608.1 - 0.0084 16.3 12.0 0.0084 16.3 12.0 2.7 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GBG70608.1 - 0.0087 15.9 10.5 0.0087 15.9 10.5 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 GBG70608.1 - 0.011 15.8 15.6 0.071 13.0 3.1 2.8 2 1 1 3 3 3 0 Seven in absentia protein family zf-RING_6 PF14835.6 GBG70608.1 - 0.022 14.6 8.5 0.087 12.7 8.5 2.1 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Glyco_hydro_20 PF00728.22 GBG70608.1 - 0.094 12.1 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, catalytic domain SPATA24 PF15175.6 GBG70608.1 - 0.14 12.1 1.1 0.21 11.4 1.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 PsaN PF05479.11 GBG70609.1 - 0.027 14.7 0.0 0.074 13.2 0.0 1.8 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Spt5_N PF11942.8 GBG70609.1 - 4.9 8.2 7.1 0.45 11.5 2.3 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Cupin_1 PF00190.22 GBG70611.1 - 3.4e-49 166.3 0.2 8.6e-32 109.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GBG70611.1 - 1.9e-06 27.5 0.4 0.016 14.9 0.0 2.6 2 0 0 2 2 2 2 Cupin domain CENP-C_C PF11699.8 GBG70611.1 - 0.00017 21.7 0.3 0.0038 17.4 0.1 2.6 2 0 0 2 2 2 1 Mif2/CENP-C like DUF1072 PF06380.11 GBG70611.1 - 0.12 12.2 0.5 0.26 11.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) Cupin_1 PF00190.22 GBG70612.1 - 1.7e-49 167.3 0.1 8.8e-32 109.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GBG70612.1 - 1.3e-07 31.2 0.1 0.0069 16.1 0.0 2.6 2 0 0 2 2 2 2 Cupin domain CENP-C_C PF11699.8 GBG70612.1 - 0.00023 21.3 0.0 0.0048 17.1 0.0 2.4 2 0 0 2 2 2 1 Mif2/CENP-C like RT_RNaseH_2 PF17919.1 GBG70613.1 - 1e-32 112.2 0.0 2.4e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70613.1 - 2.1e-30 105.9 0.0 3.6e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70613.1 - 1.4e-27 96.1 0.0 2.8e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Methyltransf_12 PF08242.12 GBG70613.1 - 1.1e-20 74.2 0.2 1.1e-15 58.2 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Integrase_H2C2 PF17921.1 GBG70613.1 - 1.6e-19 69.7 0.1 3.3e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Methyltransf_25 PF13649.6 GBG70613.1 - 1.7e-19 70.3 0.2 1.3e-13 51.4 0.0 3.4 3 1 0 3 3 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GBG70613.1 - 2.9e-17 63.0 0.0 1.1e-10 41.6 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain rve PF00665.26 GBG70613.1 - 4.5e-15 55.9 0.0 1.1e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Methyltransf_11 PF08241.12 GBG70613.1 - 5.2e-15 55.9 0.3 1.2e-10 41.9 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_16 PF10294.9 GBG70613.1 - 2.2e-14 53.6 0.1 3e-12 46.6 0.0 2.5 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_31 PF13847.6 GBG70613.1 - 8e-13 48.4 0.2 3.2e-10 40.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GBG70613.1 - 1.2e-09 37.9 0.2 0.00032 20.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Ubie_methyltran PF01209.18 GBG70613.1 - 0.00025 20.5 0.0 0.00056 19.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 GBG70613.1 - 0.0039 16.6 0.6 0.081 12.3 0.0 2.8 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) zf-H2C2 PF09337.10 GBG70613.1 - 0.0046 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Cons_hypoth95 PF03602.15 GBG70613.1 - 0.016 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF3830 PF12903.7 GBG70613.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) Methyltransf_4 PF02390.17 GBG70613.1 - 0.047 13.2 0.1 0.23 10.9 0.0 2.2 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_2 PF00891.18 GBG70613.1 - 0.061 12.6 0.2 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain DOT1 PF08123.13 GBG70613.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 NNMT_PNMT_TEMT PF01234.17 GBG70613.1 - 0.14 11.3 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Herpes_capsid PF06112.11 GBG70613.1 - 1.1 9.3 5.4 2.4 8.2 5.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RT_RNaseH_2 PF17919.1 GBG70614.1 - 1.2e-32 111.9 0.0 2.4e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70614.1 - 2e-30 106.0 0.0 3.5e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70614.1 - 1.3e-27 96.1 0.0 2.7e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70614.1 - 1.4e-19 69.9 0.1 3.2e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70614.1 - 4.5e-15 55.9 0.0 1.1e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Methyltransf_16 PF10294.9 GBG70614.1 - 1.3e-12 47.8 0.0 2.9e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GBG70614.1 - 7.9e-11 42.1 0.1 0.0003 20.7 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 GBG70614.1 - 1.7e-09 38.3 0.2 0.00019 22.1 0.1 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GBG70614.1 - 6.7e-09 36.3 0.2 0.0063 17.2 0.0 3.4 3 1 0 3 3 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GBG70614.1 - 1.9e-07 31.6 0.3 0.0048 17.5 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GBG70614.1 - 0.0035 17.1 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain zf-H2C2 PF09337.10 GBG70614.1 - 0.0045 17.2 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger MTS PF05175.14 GBG70614.1 - 0.0056 16.2 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GBG70614.1 - 0.0076 15.7 0.1 0.079 12.3 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 GBG70614.1 - 0.016 14.8 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF3830 PF12903.7 GBG70614.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) NNMT_PNMT_TEMT PF01234.17 GBG70614.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Herpes_capsid PF06112.11 GBG70614.1 - 1 9.4 5.4 2.4 8.2 5.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RT_RNaseH_2 PF17919.1 GBG70615.1 - 8.8e-31 105.9 0.0 1.9e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70615.1 - 2.6e-19 69.5 0.0 6.3e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70615.1 - 4.8e-19 68.2 0.1 9.4e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG70615.1 - 1.5e-09 37.7 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG70615.1 - 3.2e-08 33.8 0.0 8.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70615.1 - 0.0001 22.5 0.0 0.0003 20.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Mucin PF01456.17 GBG70618.1 - 2.1 8.3 7.9 7 6.6 7.9 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein HSP20 PF00011.21 GBG70619.1 - 1.8e-24 85.8 0.1 3.1e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG70619.1 - 9.3e-05 21.9 0.1 0.00044 19.8 0.1 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA MotCF PF09158.10 GBG70619.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal DUF4350 PF14258.6 GBG70619.1 - 0.16 12.4 0.1 33 5.0 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4350) rve PF00665.26 GBG70620.1 - 1.8e-10 41.0 0.0 3.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG70620.1 - 0.032 14.1 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain TBCC PF07986.12 GBG70621.1 - 6.2e-29 100.2 0.1 1e-28 99.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 GBG70621.1 - 0.06 13.0 0.5 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal Hyccin PF09790.9 GBG70623.1 - 0.0029 16.8 0.1 0.0044 16.2 0.1 1.2 1 0 0 1 1 1 1 Hyccin HLH PF00010.26 GBG70624.1 - 1.7e-14 53.5 2.8 3.2e-14 52.6 2.8 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SpoIIIAH PF12685.7 GBG70624.1 - 0.36 10.6 4.2 0.65 9.8 4.2 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein CobT PF06213.12 GBG70625.1 - 1.3 8.4 21.9 1.6 8.1 21.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 GBG70625.1 - 1.8 7.9 18.4 2 7.8 18.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG70625.1 - 2.3 6.4 18.8 2.5 6.2 18.8 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG70625.1 - 3.4 5.9 14.7 3.9 5.6 14.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG70628.1 - 2.9e-32 110.7 0.0 5.6e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70628.1 - 7.3e-26 90.5 0.0 2e-25 89.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70628.1 - 1.6e-20 73.6 0.4 3.3e-20 72.6 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG70628.1 - 1.6e-14 54.1 0.0 4.7e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG70628.1 - 7.1e-05 22.8 0.9 0.00017 21.6 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG70629.1 - 1.6e-11 43.9 0.9 2.9e-11 43.1 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_4 PF13837.6 GBG70629.1 - 1.2e-06 28.8 0.8 2.9e-06 27.6 0.8 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG70631.1 - 3e-28 98.9 0.1 4.6e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70631.1 - 1.5e-20 73.1 0.0 4.7e-15 55.5 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70631.1 - 9.4e-16 57.7 0.0 1.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG70631.1 - 1.6e-09 38.0 0.0 4.5e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG70631.1 - 6.6e-05 23.1 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Nup54 PF13874.6 GBG70634.1 - 0.02 15.0 0.6 2.7 8.1 0.1 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DNA_ligase_ZBD PF03119.16 GBG70635.1 - 0.15 12.1 0.4 0.61 10.2 0.2 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain RVT_1 PF00078.27 GBG70637.1 - 3.3e-13 49.7 0.0 6.2e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_6 PF15288.6 GBG70637.1 - 0.015 15.1 0.5 0.037 13.9 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG70638.1 - 4.8e-25 87.5 0.0 1e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TraB PF01963.17 GBG70638.1 - 2.2e-20 73.7 0.1 1.9e-19 70.6 0.0 2.4 3 0 0 3 3 3 1 TraB family RT_RNaseH PF17917.1 GBG70638.1 - 6.3e-15 55.4 0.0 1.3e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG70638.1 - 3.4e-10 40.1 0.0 7.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Myb_DNA-bind_4 PF13837.6 GBG70639.1 - 1.1e-05 25.7 3.2 1.1e-05 25.7 3.2 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70639.1 - 0.087 13.2 4.0 0.1 12.9 2.2 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG70639.1 - 0.3 11.2 4.9 0.39 10.8 3.7 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG70640.1 - 9e-28 96.9 0.0 1.4e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70640.1 - 1.2e-11 44.7 0.0 1.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70640.1 - 0.0072 16.0 0.2 0.33 10.6 0.0 2.5 2 1 0 2 2 2 1 Transposase DDE domain Beach PF02138.18 GBG70640.1 - 0.23 10.8 0.1 0.56 9.5 0.0 1.6 2 0 0 2 2 2 0 Beige/BEACH domain Integrase_H2C2 PF17921.1 GBG70641.1 - 8.4e-16 57.8 0.2 1.8e-15 56.8 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70641.1 - 5.2e-15 55.7 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70641.1 - 0.0062 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger SlyX PF04102.12 GBG70641.1 - 4.3 8.0 7.3 1.9 9.1 0.5 3.6 4 0 0 4 4 4 0 SlyX gag-asp_proteas PF13975.6 GBG70644.1 - 3.1e-06 27.7 0.2 7e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG70644.1 - 0.00035 20.4 0.1 0.00058 19.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG70644.1 - 0.00074 20.1 0.2 0.0018 18.9 0.2 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG70644.1 - 0.0081 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Mlo PF03094.15 GBG70645.1 - 1.6e-112 376.3 0.7 1.2e-84 284.4 0.1 2.4 3 0 0 3 3 3 2 Mlo family gag-asp_proteas PF13975.6 GBG70645.1 - 0.0022 18.5 0.1 0.0051 17.3 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70645.1 - 0.012 16.2 0.2 0.04 14.6 0.1 1.9 2 0 0 2 2 2 0 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG70647.1 - 6.1e-18 65.0 0.1 4.4e-11 42.7 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70647.1 - 2.3e-05 24.1 0.0 0.048 13.2 0.0 2.2 1 1 1 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70647.1 - 0.13 11.9 0.2 6.2 6.4 0.2 2.2 1 1 1 2 2 2 0 Transposase DDE domain RVT_1 PF00078.27 GBG70648.1 - 2.1e-28 99.4 0.1 3.1e-28 98.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70648.1 - 1.3e-16 60.4 1.3 2.4e-16 59.6 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG70648.1 - 7.8e-08 32.5 0.1 1.6e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70648.1 - 0.00091 19.4 0.0 0.0022 18.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG70648.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Lipin_mid PF16876.5 GBG70648.1 - 0.14 12.3 0.0 0.46 10.7 0.0 1.8 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain GYF_2 PF14237.6 GBG70649.1 - 3.4e-08 33.1 0.0 8.3e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 GYF domain 2 gag-asp_proteas PF13975.6 GBG70650.1 - 0.00023 21.7 0.1 0.00055 20.4 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG70650.1 - 0.0089 15.8 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG70650.1 - 0.017 15.7 0.1 0.044 14.4 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG70650.1 - 0.026 14.2 1.9 0.032 13.9 0.3 2.0 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like RVP_2 PF08284.11 GBG70650.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease PhoLip_ATPase_C PF16212.5 GBG70653.1 - 1.4e-69 234.6 29.8 2.2e-69 234.0 25.3 2.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GBG70653.1 - 2.8e-22 78.2 0.1 2.8e-22 78.2 0.1 2.5 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GBG70653.1 - 1.3e-07 32.1 0.1 6.9e-05 23.2 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GBG70653.1 - 2.7e-07 30.6 0.0 4.9e-06 26.5 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GBG70653.1 - 0.0013 18.2 6.3 0.0027 17.2 0.1 3.1 3 0 0 3 3 3 1 E1-E2 ATPase PhoLip_ATPase_C PF16212.5 GBG70654.1 - 1.4e-69 234.6 29.8 2.2e-69 234.0 25.3 2.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GBG70654.1 - 2.8e-22 78.2 0.1 2.8e-22 78.2 0.1 2.5 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GBG70654.1 - 1.3e-07 32.1 0.1 6.8e-05 23.3 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GBG70654.1 - 1.4e-07 31.5 0.0 2.5e-06 27.5 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GBG70654.1 - 0.0013 18.3 6.3 0.0027 17.2 0.1 3.1 3 0 0 3 3 3 1 E1-E2 ATPase DUF2358 PF10184.9 GBG70655.1 - 2.2e-13 50.5 0.0 4.9e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) PI3K_1B_p101 PF10486.9 GBG70655.1 - 0.076 10.8 9.4 0.11 10.2 9.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 GBG70655.1 - 0.12 11.7 0.8 0.17 11.1 0.8 1.2 1 0 0 1 1 1 0 NOA36 protein Ndc1_Nup PF09531.10 GBG70655.1 - 0.27 9.9 3.4 0.37 9.4 3.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4746 PF15928.5 GBG70655.1 - 1.2 8.5 4.7 1.8 7.9 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FAM176 PF14851.6 GBG70655.1 - 3.6 7.2 7.3 6.3 6.5 7.3 1.4 1 0 0 1 1 1 0 FAM176 family Apt1 PF10351.9 GBG70655.1 - 3.6 6.3 11.4 5.3 5.8 11.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 GBG70655.1 - 4.8 5.8 8.1 7.1 5.3 8.1 1.2 1 0 0 1 1 1 0 Presenilin ATP11 PF06644.11 GBG70655.1 - 6.1 6.5 6.5 10 5.8 6.5 1.4 1 0 0 1 1 1 0 ATP11 protein Zip PF02535.22 GBG70655.1 - 7 5.8 8.6 10 5.3 8.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SPX PF03105.19 GBG70655.1 - 8.8 6.1 17.9 17 5.2 17.9 1.4 1 0 0 1 1 1 0 SPX domain Transglut_core PF01841.19 GBG70656.1 - 1.9e-10 41.2 2.4 5.9e-10 39.6 2.4 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 GBG70656.1 - 9.1e-08 31.9 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PAW PF04721.17 GBG70656.1 - 0.00011 22.1 0.3 0.00019 21.3 0.3 1.4 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW ubiquitin PF00240.23 GBG70656.1 - 0.0042 16.8 0.0 0.0089 15.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family F5_F8_type_C PF00754.25 GBG70656.1 - 0.017 15.2 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain RVT_1 PF00078.27 GBG70657.1 - 5.1e-30 104.7 0.1 8.5e-30 103.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70657.1 - 2.4e-23 82.1 0.0 5.7e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70657.1 - 1.8e-20 73.2 0.0 3.6e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70657.1 - 0.00064 19.8 0.4 0.0045 17.1 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG70657.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease CutA1 PF03091.15 GBG70658.1 - 1.3e-28 98.7 0.0 2.2e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DDE_Tnp_4 PF13359.6 GBG70659.1 - 1.9e-18 66.6 0.0 5.3e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70659.1 - 3.5e-09 36.6 0.0 5.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70659.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain RAP1 PF07218.11 GBG70661.1 - 4 5.6 5.3 5.4 5.2 5.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF659 PF04937.15 GBG70662.1 - 1.7e-14 54.0 0.0 2.8e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG70662.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Chlam_PMP PF02415.17 GBG70662.1 - 1.4 9.6 9.7 5.8 7.6 0.2 5.3 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chlam_PMP PF02415.17 GBG70663.1 - 0.00063 20.1 16.4 0.054 14.0 0.8 7.7 8 1 0 8 8 8 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NosD PF05048.13 GBG70663.1 - 0.0057 15.9 2.1 0.02 14.2 1.8 1.9 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) HSP20 PF00011.21 GBG70665.1 - 4.2e-22 78.2 0.1 7e-21 74.3 0.1 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family RT_RNaseH_2 PF17919.1 GBG70665.1 - 5.5e-16 58.4 0.0 9.6e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70665.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArsA_HSP20 PF17886.1 GBG70665.1 - 4.7e-05 22.9 1.8 0.00011 21.7 1.8 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA RT_RNaseH PF17917.1 GBG70665.1 - 0.00063 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RNA_pol_Rpb2_6 PF00562.28 GBG70665.1 - 0.017 14.2 0.1 0.062 12.4 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 6 BON PF04972.17 GBG70665.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 BON domain Chlam_PMP PF02415.17 GBG70667.1 - 0.0074 16.7 0.8 0.29 11.7 0.1 7.8 8 2 0 8 8 8 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat zf-CCHC PF00098.23 GBG70668.1 - 1e-06 28.5 1.2 1.8e-06 27.7 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG70668.1 - 0.023 14.5 1.3 0.03 14.1 0.2 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG70668.1 - 0.14 12.0 0.8 0.28 11.1 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Phage_Mu_F PF04233.14 GBG70668.1 - 0.37 11.5 4.8 0.51 11.1 3.3 1.8 2 0 0 2 2 2 0 Phage Mu protein F like protein DUF1043 PF06295.12 GBG70668.1 - 0.78 9.8 3.9 1.4 8.9 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) TFIIA PF03153.13 GBG70670.1 - 0.04 13.9 10.1 0.066 13.2 10.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 GBG70670.1 - 0.36 10.1 20.6 1.3 8.2 10.3 2.1 2 0 0 2 2 2 0 BUD22 Dicty_REP PF05086.12 GBG70670.1 - 0.58 8.1 6.0 1 7.3 6.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_phi PF04931.13 GBG70670.1 - 0.84 7.7 26.2 1.9 6.5 26.2 1.5 1 0 0 1 1 1 0 DNA polymerase phi IF3_C PF00707.22 GBG70671.1 - 8e-32 109.1 0.5 1.4e-31 108.3 0.5 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 GBG70671.1 - 3.4e-27 94.5 1.7 4.9e-27 94.0 0.6 1.8 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain SNARE_assoc PF09335.11 GBG70672.1 - 3.4e-06 27.5 0.2 3.4e-06 27.5 0.2 1.8 2 0 0 2 2 1 1 SNARE associated Golgi protein Nop14 PF04147.12 GBG70672.1 - 0.0021 16.4 9.5 0.003 15.9 9.5 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG70672.1 - 0.0072 15.8 9.2 0.011 15.2 9.2 1.2 1 0 0 1 1 1 1 SDA1 DUF2052 PF09747.9 GBG70672.1 - 0.01 16.0 8.7 0.022 14.9 8.7 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NOA36 PF06524.12 GBG70672.1 - 0.036 13.4 9.9 0.056 12.8 9.9 1.2 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 GBG70672.1 - 0.099 12.0 12.1 0.19 11.0 12.1 1.5 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 GBG70672.1 - 0.11 12.1 8.3 0.18 11.3 8.3 1.3 1 0 0 1 1 1 0 PPP4R2 TFIIF_alpha PF05793.12 GBG70672.1 - 0.11 11.0 11.6 0.22 10.1 11.6 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RPN2_C PF18004.1 GBG70672.1 - 0.19 11.6 4.3 0.34 10.8 4.3 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 GBG70672.1 - 0.42 8.8 9.4 0.63 8.3 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG70672.1 - 0.53 10.1 4.8 0.95 9.2 4.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 GBG70672.1 - 1.5 7.2 15.1 2.4 6.5 15.1 1.2 1 0 0 1 1 1 0 Mpp10 protein PI3K_1B_p101 PF10486.9 GBG70672.1 - 1.8 6.2 2.8 2.5 5.7 2.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sigma70_ner PF04546.13 GBG70672.1 - 6.6 6.6 12.6 14 5.4 12.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Chlam_PMP PF02415.17 GBG70673.1 - 0.00027 21.2 35.8 0.18 12.3 0.2 7.8 8 1 0 8 8 8 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF5338 PF17273.2 GBG70674.1 - 0.14 12.3 0.1 0.37 10.9 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Iso_dh PF00180.20 GBG70675.1 - 8e-136 452.7 0.0 1.2e-135 452.2 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WD40 PF00400.32 GBG70675.1 - 3.1e-17 62.6 1.1 0.0066 17.3 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG70675.1 - 1.4e-05 25.3 0.0 2.2 8.6 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CDC37_N PF03234.14 GBG70675.1 - 0.0035 18.3 10.2 0.0063 17.4 10.2 1.3 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding RAB3GAP2_N PF14655.6 GBG70675.1 - 0.012 14.9 4.7 0.15 11.3 0.0 2.7 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIA PF03153.13 GBG70675.1 - 0.014 15.5 16.1 0.022 14.8 16.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GBG70675.1 - 0.55 9.8 20.9 0.87 9.2 20.9 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 GBG70675.1 - 0.68 10.0 17.1 17 5.5 17.1 2.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Macoilin PF09726.9 GBG70675.1 - 1.7 7.1 7.9 2.5 6.6 7.9 1.1 1 0 0 1 1 1 0 Macoilin family Roughex PF06020.11 GBG70675.1 - 2.1 7.3 11.3 3.6 6.6 11.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Androgen_recep PF02166.16 GBG70675.1 - 4.3 6.1 21.8 0.016 14.1 11.5 2.0 2 0 0 2 2 2 0 Androgen receptor Suf PF05843.14 GBG70675.1 - 6.1 6.7 9.6 10 6.0 9.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) tRNA-synt_2 PF00152.20 GBG70677.1 - 9.3e-108 360.0 0.0 1.1e-107 359.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 GBG70677.1 - 3.7e-21 75.1 0.7 1.1e-20 73.6 0.3 2.0 2 0 0 2 2 2 1 GAD domain tRNA_anti-codon PF01336.25 GBG70677.1 - 2.2e-13 50.0 0.0 5.6e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GBG70677.1 - 0.0087 15.6 0.3 0.44 10.0 0.1 2.7 2 1 0 2 2 2 1 tRNA synthetases class II core domain (F) DUF4378 PF14309.6 GBG70678.1 - 0.00054 20.4 0.5 0.00054 20.4 0.5 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4378) SPACA7 PF15307.6 GBG70678.1 - 0.093 13.0 0.1 0.093 13.0 0.1 4.1 4 1 1 5 5 5 0 Sperm acrosome-associated protein 7 RT_RNaseH_2 PF17919.1 GBG70682.1 - 3.6e-30 103.9 0.0 9.4e-30 102.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70682.1 - 4e-29 101.7 0.1 7.8e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70682.1 - 3.1e-27 94.9 0.1 5.9e-27 94.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG70682.1 - 5.4e-07 30.1 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG70682.1 - 1.1e-05 25.6 0.1 2.5e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG70682.1 - 7.8e-05 23.3 0.0 0.00017 22.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG70682.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG70682.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) HepII_C PF18675.1 GBG70682.1 - 0.13 12.3 0.1 18 5.5 0.0 3.3 3 0 0 3 3 3 0 Heparinase II C-terminal domain PA26 PF04636.13 GBG70683.1 - 0.9 8.4 7.7 1 8.2 7.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Plasmodium_Vir PF05795.11 GBG70683.1 - 3.4 7.0 5.6 3.8 6.8 5.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PSK PF06404.12 GBG70683.1 - 5 8.2 11.5 10 7.2 11.5 1.5 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) PIEZO PF15917.5 GBG70683.1 - 8.9 5.7 12.0 11 5.5 12.0 1.1 1 0 0 1 1 1 0 Piezo RT_RNaseH PF17917.1 GBG70684.1 - 1.6e-26 92.6 0.1 3e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70684.1 - 1.5e-19 69.9 0.0 3.4e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70684.1 - 1.6e-16 60.1 0.1 3.9e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70684.1 - 9.1e-12 45.2 0.1 2.2e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70684.1 - 0.0094 16.2 0.0 0.028 14.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Herpes_LMP1 PF05297.11 GBG70684.1 - 0.31 10.2 0.7 0.73 9.0 0.7 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RVT_1 PF00078.27 GBG70685.1 - 2.3e-27 96.0 0.2 4e-27 95.2 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70685.1 - 2.8e-11 43.3 0.0 5.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG70685.1 - 0.086 12.3 24.6 0.12 11.8 24.6 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG70685.1 - 0.14 11.7 14.2 0.2 11.2 14.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG70685.1 - 0.19 9.9 25.5 0.26 9.4 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG70685.1 - 0.36 9.1 20.6 0.56 8.4 20.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG70685.1 - 0.64 8.5 22.0 1 7.9 22.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LAP1C PF05609.12 GBG70685.1 - 5.8 5.9 13.3 8.3 5.4 13.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 GBG70685.1 - 6.3 6.0 27.7 9.1 5.5 27.7 1.1 1 0 0 1 1 1 0 BUD22 Glyco_hydro_10 PF00331.20 GBG70686.1 - 3.7e-48 164.3 0.2 5.9e-48 163.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 GBG70686.1 - 2.8e-27 95.7 0.0 2.5e-15 56.9 0.0 3.7 3 1 0 3 3 3 2 Carbohydrate binding domain CarboxypepD_reg PF13620.6 GBG70686.1 - 0.0032 17.7 0.4 4.2 7.7 0.0 2.7 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain Polyketide_cyc2 PF10604.9 GBG70686.1 - 0.011 16.0 0.7 0.029 14.6 0.7 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Glyco_hydro_10 PF00331.20 GBG70687.1 - 3.6e-48 164.3 0.2 5.7e-48 163.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 GBG70687.1 - 2.6e-27 95.8 0.0 2.5e-15 57.0 0.0 3.7 3 1 0 3 3 3 2 Carbohydrate binding domain CarboxypepD_reg PF13620.6 GBG70687.1 - 0.003 17.8 0.4 4.1 7.7 0.0 2.7 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain Polyketide_cyc2 PF10604.9 GBG70687.1 - 0.011 16.0 0.7 0.029 14.7 0.7 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport GCP_C_terminal PF04130.13 GBG70690.1 - 4.9e-79 266.0 0.1 6.9e-79 265.5 0.1 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GBG70690.1 - 6.7e-76 255.8 0.0 4.9e-54 184.0 0.0 2.4 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal TetR_C_11 PF16859.5 GBG70690.1 - 0.044 14.1 0.0 0.24 11.7 0.0 2.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Shugoshin_N PF07558.11 GBG70691.1 - 0.01 15.7 6.6 0.13 12.2 0.8 3.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Ku_PK_bind PF08785.11 GBG70691.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.9 2 1 1 3 3 3 0 Ku C terminal domain like NPV_P10 PF05531.12 GBG70691.1 - 1.1 9.8 3.5 1.2 9.7 1.4 2.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Trypan_glycop PF00913.19 GBG70691.1 - 1.6 8.0 13.0 1.7 7.9 7.1 2.1 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) AbiH PF14253.6 GBG70691.1 - 1.6 8.5 6.0 2.5 7.9 6.0 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH dCMP_cyt_deam_2 PF08211.12 GBG70692.1 - 1.5e-34 119.0 0.0 1.4e-33 115.9 0.0 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 GBG70692.1 - 1.2e-11 44.4 0.0 2.4e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region OTT_1508_deam PF14441.6 GBG70692.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Myc_N PF01056.18 GBG70692.1 - 0.046 13.6 0.7 0.082 12.8 0.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CAP_N PF01213.19 GBG70692.1 - 8.1 5.8 8.6 0.34 10.4 1.0 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Stevor PF17410.2 GBG70693.1 - 0.015 14.9 3.6 0.022 14.3 3.6 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame HIRAN PF08797.11 GBG70694.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain Neocarzinostat PF00960.18 GBG70694.1 - 0.028 14.4 0.2 0.091 12.7 0.2 1.8 1 0 0 1 1 1 0 Neocarzinostatin family Trypan_PARP PF05887.11 GBG70694.1 - 0.88 9.5 32.6 1.3 9.1 19.0 2.6 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Thioredoxin PF00085.20 GBG70695.1 - 1.1e-27 96.0 0.0 1.6e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG70695.1 - 4.6e-06 27.0 0.0 1.4e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG70695.1 - 0.00012 22.3 0.0 0.00077 19.7 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GBG70695.1 - 0.0022 17.8 0.1 0.003 17.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 GBG70695.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.7 1 1 1 2 2 2 0 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 GBG70695.1 - 0.092 12.4 0.1 12 5.5 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin Redoxin PF08534.10 GBG70695.1 - 0.12 12.1 0.1 0.78 9.4 0.1 1.9 1 1 1 2 2 2 0 Redoxin Glutaredoxin PF00462.24 GBG70695.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.6 GBG70695.1 - 0.17 12.1 0.1 0.46 10.7 0.1 1.6 2 0 0 2 2 2 0 Thioredoxin-like DUF4680 PF15730.5 GBG70695.1 - 1.8 8.9 8.1 56 4.1 7.8 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4680) RRM_5 PF13893.6 GBG70696.1 - 1.2e-40 138.0 1.6 1.1e-29 102.6 0.0 4.1 2 2 2 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GBG70696.1 - 2.4e-24 85.0 0.0 4.3e-07 29.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 GBG70696.1 - 1.1e-18 67.2 0.0 9.4e-18 64.2 0.1 2.3 2 0 0 2 2 2 1 RRM-like domain RL PF17797.1 GBG70696.1 - 3e-07 30.3 0.0 0.0093 15.9 0.0 3.4 3 0 0 3 3 3 2 RL domain RRM_occluded PF16842.5 GBG70696.1 - 2.3e-06 27.3 0.4 0.044 13.6 0.1 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 GBG70696.1 - 0.012 15.6 0.0 2.6 8.2 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 PPR_2 PF13041.6 GBG70697.1 - 2.2e-07 31.0 1.8 0.12 12.6 0.3 4.6 3 1 3 6 6 6 4 PPR repeat family SAP PF02037.27 GBG70697.1 - 3.2e-07 30.0 0.1 9.4e-07 28.4 0.1 1.9 1 0 0 1 1 1 1 SAP domain PPR_1 PF12854.7 GBG70697.1 - 7.8e-07 28.7 1.4 0.073 12.8 0.0 4.3 4 1 1 5 5 5 2 PPR repeat PPR_3 PF13812.6 GBG70697.1 - 2.8e-06 27.3 0.9 0.073 13.2 0.2 4.5 3 1 3 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.20 GBG70697.1 - 1.1e-05 25.4 9.1 0.057 13.7 0.0 5.7 6 1 1 7 7 7 2 PPR repeat PPR_long PF17177.4 GBG70697.1 - 0.00027 20.4 0.0 0.19 11.1 0.0 3.5 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP RT_RNaseH_2 PF17919.1 GBG70698.1 - 6.9e-34 115.9 0.1 1.3e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70698.1 - 5.4e-31 107.0 0.1 9.6e-31 106.2 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70698.1 - 2.1e-30 105.9 0.1 3.4e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG70699.1 - 3.6e-14 52.9 1.2 7.6e-14 51.9 1.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG70699.1 - 7.4e-06 26.0 0.2 1.8e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG70699.1 - 0.00043 20.5 0.4 0.00085 19.5 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG70699.1 - 0.011 15.9 1.1 0.026 14.7 0.4 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70699.1 - 0.02 15.2 0.5 0.02 15.2 0.5 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like EF-hand_7 PF13499.6 GBG70700.1 - 1e-10 41.9 2.2 9.8e-07 29.1 0.1 3.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG70700.1 - 1.4e-08 34.0 0.0 0.069 13.1 0.0 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 GBG70700.1 - 1.3e-06 27.5 0.0 0.34 10.6 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 GBG70700.1 - 0.0012 18.2 0.0 0.23 11.0 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_13 PF17958.1 GBG70700.1 - 0.076 12.8 0.0 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Myb_DNA-bind_4 PF13837.6 GBG70702.1 - 2.7e-11 43.7 0.2 5.7e-11 42.7 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG70702.1 - 0.0011 19.1 0.5 0.093 12.9 0.2 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG70702.1 - 0.0049 16.9 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG70702.1 - 0.022 15.0 0.1 0.061 13.6 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70702.1 - 0.91 9.9 2.5 0.61 10.4 0.4 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RT_RNaseH_2 PF17919.1 GBG70703.1 - 7.2e-21 74.1 0.0 1.6e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70703.1 - 7e-19 68.1 0.0 1.7e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glyoxalase PF00903.25 GBG70703.1 - 1.1e-07 32.1 0.2 3.9e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Retrotrans_gag PF03732.17 GBG70703.1 - 0.0037 17.5 0.4 0.039 14.2 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG70703.1 - 0.088 12.7 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Rz1 PF06085.11 GBG70703.1 - 1.5 8.6 7.4 1.2 9.0 2.6 2.8 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor gag-asp_proteas PF13975.6 GBG70704.1 - 4.2e-08 33.7 0.0 7.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70704.1 - 5.3e-08 33.4 0.0 1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG70704.1 - 8.1e-06 25.7 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG70704.1 - 0.00047 19.8 0.1 0.01 15.3 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG70704.1 - 0.0036 17.1 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG70705.1 - 0.0081 16.4 0.3 0.0081 16.4 0.3 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein DUF5050 PF16472.5 GBG70705.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) NPV_P10 PF05531.12 GBG70705.1 - 0.24 11.9 2.8 2 8.9 0.5 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 GBG70705.1 - 2.1 8.4 5.9 1.9 8.6 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Glyoxalase PF00903.25 GBG70706.1 - 0.14 12.4 0.1 6.8 6.9 0.0 2.3 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF765 PF05570.11 GBG70707.1 - 0.054 13.7 1.5 0.13 12.5 1.5 1.6 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) DAGAT PF03982.13 GBG70708.1 - 7.3e-49 166.3 0.0 1e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase RVT_1 PF00078.27 GBG70708.1 - 1.4e-29 103.2 0.1 1.9e-29 102.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG70708.1 - 0.2 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Myb_DNA-bind_4 PF13837.6 GBG70710.1 - 2.5e-06 27.8 3.3 4.7e-06 26.9 3.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG70710.1 - 0.0022 18.2 1.1 0.0054 17.0 1.1 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF3472 PF11958.8 GBG70710.1 - 0.0067 16.9 0.6 0.0067 16.9 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3472) Myb_DNA-bind_5 PF13873.6 GBG70710.1 - 0.0093 16.0 0.4 0.0093 16.0 0.4 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG70710.1 - 0.024 14.8 0.0 0.088 13.0 0.1 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70710.1 - 0.026 14.9 0.3 0.051 13.9 0.3 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Herpes_UL32 PF06070.11 GBG70710.1 - 0.16 9.7 4.2 0.034 11.9 0.8 1.6 2 0 0 2 2 2 0 Herpesvirus large structural phosphoprotein UL32 Pox_F15 PF04596.12 GBG70710.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus protein F15 Spt5_N PF11942.8 GBG70710.1 - 8.8 7.4 10.9 0.19 12.7 1.7 2.7 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal LamB_YcsF PF03746.16 GBG70711.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 LamB/YcsF family Retrotrans_gag PF03732.17 GBG70714.1 - 0.0054 17.0 0.2 0.012 15.8 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF659 PF04937.15 GBG70716.1 - 4.5e-16 59.1 0.0 8e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG70718.1 - 0.0021 18.1 5.4 0.0021 18.1 5.4 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG70718.1 - 0.0028 17.4 2.4 0.0028 17.4 2.4 2.0 2 0 0 2 2 2 1 Zinc knuckle DUF4800 PF16057.5 GBG70718.1 - 0.0074 15.6 5.5 0.041 13.1 6.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) LMBR1 PF04791.16 GBG70718.1 - 3.4 6.5 5.2 4 6.2 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Integrase_H2C2 PF17921.1 GBG70719.1 - 0.01 16.0 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Integrase zinc binding domain Myb_DNA-bind_4 PF13837.6 GBG70720.1 - 7.4e-10 39.1 0.7 1.5e-09 38.1 0.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG70720.1 - 0.6 10.2 2.6 1.2 9.3 1.8 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG70721.1 - 2.6e-31 108.4 0.0 4e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70721.1 - 8.6e-14 51.6 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70721.1 - 0.00035 20.3 0.1 0.056 13.1 0.0 2.6 2 1 0 2 2 2 2 Transposase DDE domain DUF659 PF04937.15 GBG70722.1 - 4.3e-08 33.2 0.0 7.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG70723.1 - 0.00033 20.9 0.2 0.00033 20.9 0.2 3.3 3 1 0 3 3 3 1 Retrotransposon gag protein Caudo_TAP PF02413.17 GBG70723.1 - 1.8 8.7 8.9 0.55 10.4 1.4 2.7 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK RVT_1 PF00078.27 GBG70724.1 - 1.9e-35 122.4 0.0 3.1e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70724.1 - 4e-31 107.0 0.0 1.1e-30 105.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70724.1 - 3.1e-30 104.6 0.0 6.3e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70724.1 - 0.00028 20.9 0.0 0.00063 19.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain SusD-like PF12741.7 GBG70724.1 - 0.036 13.0 0.1 0.05 12.5 0.1 1.1 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein Peptidase_C48 PF02902.19 GBG70725.1 - 4.5e-19 69.1 1.2 2.7e-18 66.6 1.2 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CDP-OH_P_transf PF01066.21 GBG70727.1 - 2.9e-12 47.2 0.3 7.2e-12 45.9 0.3 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PCNA_N PF00705.18 GBG70728.1 - 3e-58 195.1 5.2 1.8e-52 176.3 0.7 2.2 1 1 1 2 2 2 2 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 GBG70728.1 - 1.2e-26 93.4 0.3 3.2e-26 92.0 0.2 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 GBG70728.1 - 1.3e-06 27.7 0.1 1.7e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 GBG70728.1 - 0.00023 20.7 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 2 Rad9 Reeler PF02014.16 GBG70728.1 - 0.021 15.6 0.0 0.038 14.7 0.0 1.5 1 1 0 1 1 1 0 Reeler domain PCNA_N PF00705.18 GBG70729.1 - 4.2e-59 197.8 2.7 5.8e-59 197.4 2.7 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 GBG70729.1 - 9.2e-27 93.7 0.2 2.8e-26 92.2 0.2 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 GBG70729.1 - 1.1e-05 24.7 0.1 0.00015 20.9 0.1 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 GBG70729.1 - 7.7e-05 22.3 0.0 0.00014 21.4 0.0 1.4 1 1 0 1 1 1 1 Rad9 zf-CCHC PF00098.23 GBG70730.1 - 5.4e-07 29.4 2.6 5.4e-07 29.4 2.6 2.0 2 0 0 2 2 2 1 Zinc knuckle E6 PF00518.17 GBG70731.1 - 0.015 15.7 1.0 0.015 15.7 1.0 1.8 2 0 0 2 2 2 0 Early Protein (E6) DUF3456 PF11938.8 GBG70731.1 - 0.065 13.8 16.2 0.048 14.2 11.4 2.7 2 1 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP Fz PF01392.22 GBG70731.1 - 9.2 6.9 7.3 6.6 7.4 1.9 2.8 2 1 1 3 3 3 0 Fz domain DOT1 PF08123.13 GBG70732.1 - 0.0032 17.0 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 DOT1 PF08123.13 GBG70733.1 - 0.0032 17.0 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 CDP-OH_P_transf PF01066.21 GBG70734.1 - 2.9e-18 66.4 0.0 2.9e-18 66.4 0.0 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Paf1 PF03985.13 GBG70736.1 - 6.9e-52 176.9 39.9 6.9e-52 176.9 39.9 5.1 2 1 2 4 4 4 1 Paf1 Ribosomal_L29 PF00831.23 GBG70737.1 - 2.6e-14 52.9 2.0 4e-14 52.3 2.0 1.3 1 0 0 1 1 1 1 Ribosomal L29 protein SDA1 PF05285.12 GBG70739.1 - 0.0043 16.5 25.0 0.0046 16.4 25.0 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG70739.1 - 0.017 13.4 23.9 0.019 13.2 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG70739.1 - 0.039 13.3 25.1 0.051 12.9 25.1 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 GBG70739.1 - 0.087 12.1 16.2 0.16 11.3 16.2 1.4 1 0 0 1 1 1 0 NOA36 protein TFIIF_alpha PF05793.12 GBG70739.1 - 0.092 11.3 24.0 0.11 11.0 24.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPP4R2 PF09184.11 GBG70739.1 - 0.11 12.1 19.8 0.18 11.4 19.8 1.3 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 GBG70739.1 - 0.16 10.2 17.4 0.24 9.6 17.4 1.3 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 GBG70739.1 - 0.19 11.5 11.0 0.26 11.1 11.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Raftlin PF15250.6 GBG70739.1 - 0.83 8.3 6.6 0.88 8.2 6.6 1.2 1 0 0 1 1 1 0 Raftlin Cwf_Cwc_15 PF04889.12 GBG70739.1 - 1.3 8.7 23.0 1.8 8.2 23.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SURF2 PF05477.11 GBG70739.1 - 1.5 8.5 12.0 1.9 8.1 12.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RR_TM4-6 PF06459.12 GBG70739.1 - 1.5 8.6 15.7 2.1 8.1 15.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LAP1C PF05609.12 GBG70739.1 - 1.9 7.5 13.1 2.4 7.2 13.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Zip PF02535.22 GBG70739.1 - 3.7 6.7 6.8 4.5 6.4 6.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 GBG70739.1 - 4 6.1 8.8 4.9 5.8 8.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GBG70739.1 - 4.3 6.0 12.0 5.1 5.8 12.0 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG70739.1 - 4.9 5.8 10.4 5.9 5.6 10.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 GBG70739.1 - 6.9 6.0 27.8 12 5.1 27.8 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 GBG70739.1 - 6.9 5.5 7.4 9.4 5.1 7.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Lin-8 PF03353.15 GBG70739.1 - 7.2 6.1 16.0 11 5.5 16.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4778 PF16008.5 GBG70742.1 - 0.23 11.5 6.4 0.28 11.2 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) AAA_13 PF13166.6 GBG70742.1 - 0.44 9.1 10.1 0.56 8.8 10.1 1.1 1 0 0 1 1 1 0 AAA domain DivIVA PF05103.13 GBG70742.1 - 1.1 9.3 11.7 1.1 9.3 10.1 1.7 1 1 1 2 2 2 0 DivIVA protein DUF2381 PF09544.10 GBG70742.1 - 1.9 7.9 12.7 0.25 10.9 8.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2381) Sox_N PF12444.8 GBG70742.1 - 9.8 7.4 7.5 1.3 10.2 0.4 2.6 2 0 0 2 2 2 0 Sox developmental protein N terminal CDC45 PF02724.14 GBG70743.1 - 0.00093 17.6 23.2 0.0012 17.3 23.2 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 GBG70743.1 - 0.017 14.5 30.4 0.022 14.1 30.4 1.1 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 GBG70743.1 - 0.039 12.6 32.7 0.054 12.1 32.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 GBG70743.1 - 0.052 12.3 14.3 0.067 11.9 14.3 1.1 1 0 0 1 1 1 0 Presenilin AAR2 PF05282.11 GBG70743.1 - 0.091 12.2 4.8 0.14 11.6 4.8 1.3 1 0 0 1 1 1 0 AAR2 protein Nop14 PF04147.12 GBG70743.1 - 0.3 9.2 36.1 0.39 8.9 36.1 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG70743.1 - 0.71 8.2 33.7 1 7.7 33.7 1.2 1 0 0 1 1 1 0 Mpp10 protein Serinc PF03348.15 GBG70743.1 - 1.3 7.8 2.4 1.7 7.4 2.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SDA1 PF05285.12 GBG70743.1 - 4.5 6.6 39.7 6.2 6.1 39.7 1.1 1 0 0 1 1 1 0 SDA1 Neur_chan_memb PF02932.16 GBG70743.1 - 7.8 6.5 5.8 11 6.0 5.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RWD PF05773.22 GBG70745.1 - 0.00022 21.5 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 RWD domain JAKMIP_CC3 PF16034.5 GBG70747.1 - 0.0072 16.3 0.5 0.014 15.4 0.5 1.3 1 0 0 1 1 1 1 JAKMIP CC3 domain FlxA PF14282.6 GBG70747.1 - 0.019 14.9 0.6 0.045 13.8 0.6 1.6 1 0 0 1 1 1 0 FlxA-like protein DUF3450 PF11932.8 GBG70747.1 - 0.047 13.0 1.6 0.079 12.2 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 GBG70747.1 - 0.069 13.2 2.3 0.12 12.4 2.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.6 GBG70747.1 - 0.095 12.1 3.4 0.14 11.6 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) MPS2 PF17060.5 GBG70747.1 - 0.1 11.8 2.7 0.16 11.2 2.7 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Rootletin PF15035.6 GBG70747.1 - 0.23 11.5 2.7 0.37 10.8 2.7 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.11 GBG70747.1 - 0.67 10.1 5.0 0.29 11.3 2.0 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APC_N_CC PF16689.5 GBG70747.1 - 2.1 8.5 3.9 4.1 7.5 3.9 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Cnn_1N PF07989.11 GBG70747.1 - 8.1 6.7 8.1 18 5.6 8.1 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Cwf_Cwc_15 PF04889.12 GBG70748.1 - 0.47 10.1 15.9 0.69 9.6 15.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG70748.1 - 0.71 8.1 10.5 0.94 7.7 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG70748.1 - 1.6 6.8 15.0 2.2 6.4 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 GBG70748.1 - 3.3 6.1 7.1 4.5 5.7 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GBG70748.1 - 4.9 5.1 16.2 6.8 4.7 16.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Bcl-2_BAD PF10514.9 GBG70748.1 - 10 6.6 9.1 23 5.4 8.9 1.7 1 1 1 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD LZ3wCH PF18517.1 GBG70749.1 - 1.1e-20 73.5 0.4 1.6e-20 72.9 0.4 1.3 1 0 0 1 1 1 1 Leucine zipper with capping helix domain MHB PF16525.5 GBG70749.1 - 0.031 14.5 0.1 0.85 9.9 0.1 2.1 2 0 0 2 2 2 0 Haemophore, haem-binding MRP-L28 PF09812.9 GBG70749.1 - 0.095 12.8 0.1 0.14 12.2 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 Retrotrans_gag PF03732.17 GBG70750.1 - 0.0031 17.8 1.2 0.018 15.3 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG70750.1 - 0.029 14.1 1.0 0.076 12.8 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Lipin_mid PF16876.5 GBG70750.1 - 0.041 14.0 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain eIF-3_zeta PF05091.12 GBG70751.1 - 7.9e-202 671.8 0.0 9e-202 671.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 GBG70751.1 - 1.3e-06 28.1 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Peptidase_S28 PF05577.12 GBG70752.1 - 0.0051 15.7 0.0 0.0061 15.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF2062 PF09835.9 GBG70752.1 - 0.015 15.1 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) PepSY_TM PF03929.16 GBG70752.1 - 0.037 13.7 0.1 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Glt_symporter PF03616.14 GBG70752.1 - 0.097 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter FeoB_associated PF12669.7 GBG70752.1 - 0.098 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein RVT_1 PF00078.27 GBG70753.1 - 1.1e-27 97.0 0.1 1.9e-27 96.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70753.1 - 1.2e-15 57.4 0.0 2.7e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70753.1 - 2e-06 28.0 0.0 4.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Cwf_Cwc_15 PF04889.12 GBG70753.1 - 0.0029 17.4 23.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein RVP_2 PF08284.11 GBG70753.1 - 0.004 16.9 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG70753.1 - 0.008 16.7 0.1 0.019 15.5 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG70753.1 - 0.016 15.0 0.2 0.027 14.3 0.2 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG70753.1 - 0.021 15.5 0.1 0.053 14.2 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease TFIIF_alpha PF05793.12 GBG70753.1 - 6.8 5.2 24.1 13 4.2 24.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF1_Zn_bind PF09416.10 GBG70754.1 - 9.8e-70 233.4 8.0 1.1e-69 233.3 6.0 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 GBG70754.1 - 1.5e-58 197.7 0.0 3.1e-58 196.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG70754.1 - 1.5e-48 165.9 15.1 8.1e-28 97.9 0.4 3.3 2 1 1 3 3 3 2 AAA domain DUF5599 PF18141.1 GBG70754.1 - 1.1e-33 115.3 0.0 4.5e-33 113.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 GBG70754.1 - 2.5e-15 56.7 0.7 2e-14 53.7 0.7 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG70754.1 - 4.6e-10 40.0 0.1 1.5e-09 38.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 GBG70754.1 - 2.2e-05 24.5 0.0 2.2e-05 24.5 0.0 1.8 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 GBG70754.1 - 0.00024 21.0 0.1 0.00024 21.0 0.1 2.5 2 0 0 2 2 2 1 Helicase DUF2075 PF09848.9 GBG70754.1 - 0.00051 19.4 0.1 0.00051 19.4 0.1 2.8 4 0 0 4 4 3 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 GBG70754.1 - 0.0014 18.9 0.1 0.029 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GBG70754.1 - 0.0035 16.8 0.0 0.008 15.7 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein DUF2722 PF10846.8 GBG70754.1 - 0.0037 16.3 9.0 0.0037 16.3 9.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF2722) DEAD PF00270.29 GBG70754.1 - 0.0053 16.6 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 GBG70754.1 - 0.012 15.0 0.0 0.04 13.3 0.0 1.8 2 0 0 2 2 2 0 KaiC SRP54 PF00448.22 GBG70754.1 - 0.017 14.7 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.14 GBG70754.1 - 0.019 14.2 0.1 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase DUF4770 PF15994.5 GBG70754.1 - 0.063 13.5 2.7 0.18 12.0 2.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) NACHT PF05729.12 GBG70754.1 - 0.065 13.1 0.2 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 GBG70754.1 - 0.077 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 GBG70754.1 - 0.1 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 GBG70754.1 - 0.15 12.4 1.5 0.22 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain DUF3408 PF11888.8 GBG70754.1 - 1.2 9.3 6.8 34 4.6 7.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Presenilin PF01080.17 GBG70754.1 - 2.7 6.7 4.3 4.5 5.9 4.3 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 GBG70754.1 - 4.8 6.7 31.8 0.62 9.6 22.7 2.3 2 0 0 2 2 2 0 Spt20 family Myb_DNA-bind_4 PF13837.6 GBG70755.1 - 1.2e-05 25.6 2.1 1.8e-05 25.0 2.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG70755.1 - 0.00063 19.8 1.4 0.00095 19.2 1.4 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG70755.1 - 0.051 13.8 1.7 0.88 9.8 1.2 3.0 2 1 0 2 2 2 0 Myb-like DNA-binding domain Alpha-amyl_C2 PF07821.12 GBG70755.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain Myb_DNA-bind_6 PF13921.6 GBG70755.1 - 0.12 12.6 1.1 0.85 9.9 1.1 2.4 1 1 0 1 1 1 0 Myb-like DNA-binding domain Pectinesterase PF01095.19 GBG70756.1 - 1.7e-61 207.5 0.0 6.5e-61 205.6 0.0 1.8 1 1 0 1 1 1 1 Pectinesterase SDA1 PF05285.12 GBG70756.1 - 0.006 16.1 9.9 0.0088 15.5 9.9 1.2 1 0 0 1 1 1 1 SDA1 DUF2052 PF09747.9 GBG70756.1 - 0.016 15.3 14.5 0.036 14.2 14.5 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PMEI PF04043.15 GBG70756.1 - 0.019 15.3 0.2 0.035 14.4 0.2 1.4 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor BUD22 PF09073.10 GBG70756.1 - 0.026 13.9 10.7 0.039 13.3 10.7 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG70756.1 - 0.032 12.5 11.4 0.046 12.0 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein FYDLN_acid PF09538.10 GBG70756.1 - 0.092 13.4 9.9 0.23 12.2 9.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4834 PF16118.5 GBG70756.1 - 0.13 13.2 5.4 5.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PPP4R2 PF09184.11 GBG70756.1 - 0.16 11.6 11.2 0.23 11.0 11.2 1.2 1 0 0 1 1 1 0 PPP4R2 SpoIIP PF07454.11 GBG70756.1 - 0.16 11.4 5.2 0.78 9.1 4.8 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TFIIF_alpha PF05793.12 GBG70756.1 - 0.18 10.4 16.6 0.3 9.7 16.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.6 GBG70756.1 - 0.32 10.6 11.9 3.6 7.2 12.1 2.3 2 0 0 2 2 2 0 FAM176 family RPA43_OB PF17875.1 GBG70756.1 - 0.35 11.5 3.4 0.73 10.5 3.4 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Mpp10 PF04006.12 GBG70756.1 - 0.54 8.7 18.4 0.78 8.1 18.4 1.1 1 0 0 1 1 1 0 Mpp10 protein Conotoxin PF02950.17 GBG70756.1 - 0.54 11.3 1.9 51 5.0 1.0 2.5 2 0 0 2 2 2 0 Conotoxin Myc_N PF01056.18 GBG70756.1 - 0.79 9.6 8.1 1.6 8.5 8.1 1.5 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.13 GBG70756.1 - 0.97 7.4 21.8 1.4 6.9 21.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi RR_TM4-6 PF06459.12 GBG70756.1 - 1.5 8.5 12.1 2.5 7.9 12.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sigma70_ner PF04546.13 GBG70756.1 - 1.7 8.5 14.7 3.1 7.6 14.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Paf1 PF03985.13 GBG70756.1 - 2.1 7.3 21.8 3.5 6.5 21.8 1.2 1 0 0 1 1 1 0 Paf1 OAD_gamma PF04277.13 GBG70756.1 - 2.3 8.9 4.4 2.1 9.0 1.3 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF1676 PF07898.13 GBG70756.1 - 5 7.1 6.9 8.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Synaptobrevin PF00957.21 GBG70756.1 - 6.1 6.7 5.0 12 5.8 5.0 1.4 1 0 0 1 1 1 0 Synaptobrevin eIF-3c_N PF05470.12 GBG70756.1 - 6.1 5.0 7.1 9.3 4.4 7.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 GBG70756.1 - 7.7 4.6 20.3 11 4.0 20.3 1.1 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.12 GBG70756.1 - 9.8 5.6 10.2 17 4.7 10.2 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Peptidase_C13 PF01650.18 GBG70757.1 - 8.4e-101 336.8 0.0 1.1e-100 336.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 GBG70757.1 - 0.02 14.8 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Caspase domain RVT_1 PF00078.27 GBG70758.1 - 1.2e-28 100.2 0.1 2.5e-28 99.1 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70758.1 - 2e-19 69.5 0.5 3.7e-19 68.6 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG70758.1 - 6.5e-10 38.9 0.0 1.6e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG70758.1 - 8.8e-08 32.0 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70758.1 - 1.6e-06 28.7 0.0 4.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70758.1 - 0.00013 22.5 0.0 0.00035 21.1 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG70758.1 - 0.00018 21.8 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG70758.1 - 0.00058 20.1 0.0 0.0037 17.5 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG70758.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF5338 PF17273.2 GBG70759.1 - 0.067 13.3 0.0 1.2 9.2 0.0 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5338) Pkinase PF00069.25 GBG70760.1 - 1.3e-37 129.6 0.0 2.9e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70760.1 - 1.9e-33 115.8 0.0 9.2e-33 113.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GBG70760.1 - 0.00092 19.2 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG70760.1 - 0.0028 16.5 0.0 0.0047 15.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase EphA2_TM PF14575.6 GBG70760.1 - 0.023 15.6 0.1 44 5.0 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 GBG70760.1 - 0.042 13.7 2.1 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 Herpes_gE PF02480.16 GBG70760.1 - 0.12 11.1 0.0 0.34 9.6 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF4381 PF14316.6 GBG70760.1 - 0.95 9.7 3.4 25 5.1 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) GTP1_OBG PF01018.22 GBG70760.1 - 7 6.2 7.7 2.2 7.9 1.6 2.7 3 0 0 3 3 3 0 GTP1/OBG MDM1 PF15501.6 GBG70763.1 - 0.00029 20.1 4.6 0.0004 19.7 4.6 1.2 1 0 0 1 1 1 1 Nuclear protein MDM1 Myb_DNA-bind_4 PF13837.6 GBG70763.1 - 0.00044 20.6 4.9 0.00044 20.6 4.9 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SDA1 PF05285.12 GBG70763.1 - 0.0008 18.9 19.3 0.0014 18.2 19.3 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG70763.1 - 0.023 13.0 16.4 0.037 12.3 16.4 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG70763.1 - 0.044 12.4 23.8 0.081 11.5 23.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.13 GBG70763.1 - 0.097 12.8 25.2 0.075 13.1 20.2 2.3 2 0 0 2 2 2 0 YL1 nuclear protein BUD22 PF09073.10 GBG70763.1 - 0.28 10.5 27.9 0.0082 15.5 21.5 1.6 2 0 0 2 2 2 0 BUD22 RNA_pol_Rpc4 PF05132.14 GBG70763.1 - 0.35 11.3 4.4 0.9 10.0 4.4 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mpp10 PF04006.12 GBG70763.1 - 0.48 8.8 28.7 0.77 8.1 28.7 1.2 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 GBG70763.1 - 0.67 8.7 5.8 1.1 8.0 5.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 GBG70763.1 - 2.3 7.4 5.5 3.4 6.8 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2151 PF10221.9 GBG70763.1 - 3 6.3 6.5 4.5 5.8 6.5 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Raftlin PF15250.6 GBG70763.1 - 3.8 6.1 7.4 6.4 5.4 7.4 1.3 1 0 0 1 1 1 0 Raftlin PPP4R2 PF09184.11 GBG70763.1 - 4.4 6.8 25.9 8.6 5.8 25.9 1.4 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 GBG70763.1 - 9.8 4.6 16.8 15 3.9 16.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDE_Tnp_4 PF13359.6 GBG70764.1 - 3.9e-25 88.4 0.0 8.3e-25 87.3 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70764.1 - 5.6e-13 49.0 0.0 8.9e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70764.1 - 0.00065 19.4 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain Pkinase PF00069.25 GBG70765.1 - 3.1e-25 89.0 0.0 8.3e-25 87.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70765.1 - 9e-24 84.1 0.0 1.6e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG70765.1 - 0.99 10.4 9.0 10 7.2 0.0 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat DUF2076 PF09849.9 GBG70766.1 - 1.7 8.6 12.0 2.1 8.3 12.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) GRP PF07172.11 GBG70766.1 - 8.6 7.1 9.4 14 6.4 9.4 1.4 1 1 0 1 1 1 0 Glycine rich protein family Myb_DNA-bind_4 PF13837.6 GBG70767.1 - 3.1e-11 43.5 0.2 5.9e-11 42.6 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 GBG70767.1 - 0.062 14.3 0.1 0.12 13.4 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG70767.1 - 0.065 13.5 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF659 PF04937.15 GBG70768.1 - 6e-06 26.2 0.0 9.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG70769.1 - 3.7e-11 43.0 0.0 5.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LAP1C PF05609.12 GBG70769.1 - 1.5 7.8 7.5 2.1 7.4 7.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG70769.1 - 4.1 5.5 16.2 5.4 5.1 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG70769.1 - 5.2 6.4 16.4 6.6 6.1 16.4 1.1 1 0 0 1 1 1 0 SDA1 RT_RNaseH PF17917.1 GBG70771.1 - 2.3e-22 79.2 0.1 5.3e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70771.1 - 3.2e-19 69.3 0.2 5.5e-19 68.6 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG70771.1 - 1.2e-13 51.0 0.0 5.1e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG70771.1 - 4.4e-12 45.9 0.0 9.3e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG70771.1 - 0.0093 16.2 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG70772.1 - 3.9e-32 110.3 0.2 3.5e-31 107.2 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70772.1 - 6e-29 100.4 1.1 1.9e-28 98.8 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70772.1 - 2.1e-11 43.8 0.1 3e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) eIF3_p135 PF12807.7 GBG70773.1 - 0.088 12.8 4.9 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 zf-CCHC PF00098.23 GBG70773.1 - 0.4 10.9 1.8 1 9.6 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle ECH_2 PF16113.5 GBG70773.1 - 0.5 9.8 6.9 0.59 9.6 6.3 1.3 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase CAP_N PF01213.19 GBG70775.1 - 5.6 6.3 9.9 12 5.3 9.9 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA PF00004.29 GBG70776.1 - 2.2e-56 189.9 0.0 5.7e-39 133.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 GBG70776.1 - 5.5e-21 74.8 1.3 1.1e-20 73.9 1.3 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 GBG70776.1 - 1.6e-08 35.2 8.2 0.0062 16.9 0.0 4.5 3 2 2 5 5 5 2 AAA ATPase domain IstB_IS21 PF01695.17 GBG70776.1 - 6.4e-06 26.0 0.0 0.08 12.7 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 GBG70776.1 - 5.9e-05 23.6 0.0 0.99 10.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 GBG70776.1 - 0.00013 22.1 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 GBG70776.1 - 0.00014 21.8 0.0 0.13 12.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 GBG70776.1 - 0.00026 21.0 0.3 0.11 12.4 0.0 3.7 3 1 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 GBG70776.1 - 0.00058 20.2 0.0 1.3 9.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase PEX-2N PF09263.10 GBG70776.1 - 0.0012 19.2 0.0 0.0053 17.1 0.0 2.2 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_25 PF13481.6 GBG70776.1 - 0.0021 17.7 13.6 0.46 10.0 0.1 4.5 3 2 0 4 4 3 2 AAA domain Bac_DnaA PF00308.18 GBG70776.1 - 0.0049 16.7 0.0 2.9 7.7 0.0 2.5 3 0 0 3 3 2 1 Bacterial dnaA protein AAA_22 PF13401.6 GBG70776.1 - 0.0068 16.7 1.4 3.3 8.0 0.1 4.0 3 2 1 4 4 3 1 AAA domain ATPase_2 PF01637.18 GBG70776.1 - 0.008 16.1 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RuvB_N PF05496.12 GBG70776.1 - 0.0086 15.8 0.0 1.9 8.2 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GBG70776.1 - 0.012 15.7 0.0 0.13 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 GBG70776.1 - 0.012 16.1 0.0 4.9 7.7 0.0 3.7 4 0 0 4 4 3 0 ABC transporter AAA_29 PF13555.6 GBG70776.1 - 0.017 14.9 0.0 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain NST1 PF13945.6 GBG70776.1 - 0.03 14.4 1.2 0.064 13.4 1.2 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator TsaE PF02367.17 GBG70776.1 - 0.031 14.3 0.0 3.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CobU PF02283.16 GBG70776.1 - 0.034 13.7 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Zeta_toxin PF06414.12 GBG70776.1 - 0.055 12.7 0.1 6.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 GBG70776.1 - 0.084 12.4 0.0 15 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 GBG70776.1 - 0.088 12.2 0.5 11 5.3 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2052 PF09747.9 GBG70776.1 - 0.096 12.8 13.9 0.62 10.2 2.8 2.6 3 0 0 3 3 2 0 Coiled-coil domain containing protein (DUF2052) DUF815 PF05673.13 GBG70776.1 - 0.1 11.7 0.0 9.2 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.13 GBG70776.1 - 0.11 11.7 0.1 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain Rad17 PF03215.15 GBG70776.1 - 0.18 11.7 0.0 0.65 9.9 0.0 1.9 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_11 PF13086.6 GBG70776.1 - 0.22 11.2 0.6 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Spt5_N PF11942.8 GBG70776.1 - 1.1 10.2 18.5 2.9 8.9 7.4 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal HlyD_2 PF12700.7 GBG70777.1 - 0.21 10.3 5.4 0.28 9.9 5.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Hrs_helical PF12210.8 GBG70777.1 - 1.1 9.8 11.8 6.3 7.4 7.9 2.4 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate 5_nucleotid PF05761.14 GBG70777.1 - 2.3 7.1 6.9 3.6 6.4 6.9 1.2 1 0 0 1 1 1 0 5' nucleotidase family FAM184 PF15665.5 GBG70777.1 - 4.6 7.0 19.1 1.4 8.7 6.7 2.5 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B RT_RNaseH_2 PF17919.1 GBG70778.1 - 1.6e-29 101.8 0.0 3.4e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70778.1 - 1.8e-26 92.4 0.0 3.3e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70778.1 - 2.5e-26 92.6 0.1 4.1e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG70778.1 - 6.3e-17 61.9 0.0 1.3e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG70778.1 - 6.7e-13 48.5 0.2 1.9e-12 47.1 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG70778.1 - 5.4e-05 23.3 0.1 0.00039 20.6 0.0 2.6 3 0 0 3 3 3 1 H2C2 zinc finger rve_3 PF13683.6 GBG70778.1 - 0.066 13.0 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain tRNA_lig_CPD PF08302.11 GBG70778.1 - 0.074 12.5 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain WD40 PF00400.32 GBG70779.1 - 2.4e-05 25.0 4.6 0.039 14.8 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2730 PF10805.8 GBG70779.1 - 0.082 13.0 5.4 0.29 11.3 5.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) WHEP-TRS PF00458.20 GBG70779.1 - 0.55 10.4 5.7 0.87 9.8 2.5 2.4 1 1 1 2 2 2 0 WHEP-TRS domain WD40_alt PF14077.6 GBG70779.1 - 0.71 9.8 13.6 11 6.0 0.6 4.2 1 1 3 4 4 4 0 Alternative WD40 repeat motif Bac_small_YrzI PF09501.10 GBG70779.1 - 7.9 6.7 6.8 11 6.2 0.3 3.0 1 1 2 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) WD40 PF00400.32 GBG70780.1 - 1.6e-09 38.2 9.3 1.8e-05 25.4 0.2 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG70780.1 - 0.004 17.4 0.3 0.015 15.6 0.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG70780.1 - 0.011 14.4 0.0 0.086 11.5 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 RVT_1 PF00078.27 GBG70781.1 - 1.2e-36 126.3 0.0 1.9e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG70782.1 - 4.9e-05 23.5 5.5 7.6e-05 22.9 0.1 3.2 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG70783.1 - 7.4e-29 99.7 0.0 1.4e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70783.1 - 6.5e-25 87.5 0.0 1.4e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70783.1 - 2.4e-19 69.2 0.2 9.4e-19 67.3 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG70783.1 - 2.2e-16 60.1 0.0 3.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG70783.1 - 7.5e-10 39.0 0.0 2.6e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DUF659 PF04937.15 GBG70784.1 - 3.9e-33 114.5 0.0 5.7e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG70784.1 - 6.4e-10 38.7 0.2 1.4e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVP_2 PF08284.11 GBG70785.1 - 2.6e-06 27.2 0.0 6.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70785.1 - 7.3e-05 23.3 0.0 0.00021 21.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70785.1 - 0.0078 16.7 0.0 0.023 15.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SlyX PF04102.12 GBG70785.1 - 0.16 12.6 5.0 0.82 10.3 0.6 2.8 1 1 1 2 2 2 0 SlyX Retrotrans_gag PF03732.17 GBG70786.1 - 0.0046 17.2 0.5 0.043 14.1 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG70786.1 - 0.064 13.0 0.4 0.064 13.0 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) CAP PF00188.26 GBG70786.1 - 0.14 13.0 0.9 0.38 11.6 0.9 1.7 1 0 0 1 1 1 0 Cysteine-rich secretory protein family TRPM_tetra PF16519.5 GBG70786.1 - 1.1 9.4 3.9 8.1 6.6 0.1 2.7 2 1 0 2 2 2 0 Tetramerisation domain of TRPM Seryl_tRNA_N PF02403.22 GBG70786.1 - 6.5 7.0 9.0 14 5.9 5.9 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GRP PF07172.11 GBG70787.1 - 0.018 15.7 11.1 0.018 15.7 11.1 1.7 2 0 0 2 2 2 0 Glycine rich protein family Herpes_gE PF02480.16 GBG70787.1 - 0.089 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 GBG70787.1 - 0.16 12.9 0.0 1.5 9.8 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 GBG70787.1 - 0.2 11.9 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pkinase PF00069.25 GBG70788.1 - 1.8e-29 102.9 0.0 4.5e-29 101.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70788.1 - 3e-27 95.5 0.0 4.6e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG70788.1 - 0.0035 17.3 0.7 0.08 12.9 0.2 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG70788.1 - 0.029 13.1 0.0 0.061 12.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase DUF3040 PF11239.8 GBG70788.1 - 0.047 14.0 1.0 0.11 12.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Pkinase PF00069.25 GBG70790.1 - 4.5e-11 42.6 0.0 6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70790.1 - 5.3e-10 39.0 0.0 6.4e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1180 PF06679.12 GBG70790.1 - 1.4 9.3 5.4 0.77 10.2 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DDE_Tnp_4 PF13359.6 GBG70796.1 - 3.3e-30 104.9 0.1 5.9e-29 100.8 0.0 2.7 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70796.1 - 1.3e-14 54.3 0.0 2.2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70796.1 - 0.024 14.3 0.0 0.85 9.2 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG70797.1 - 5.5e-05 23.5 0.3 0.00012 22.4 0.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 GBG70799.1 - 1.3e-37 129.6 0.0 2.3e-37 128.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70799.1 - 2.8e-35 121.9 0.0 1.3e-34 119.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG70799.1 - 0.0048 15.7 0.0 0.0093 14.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG70799.1 - 0.0084 16.1 0.0 0.47 10.3 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Phytase-like PF13449.6 GBG70799.1 - 0.024 14.6 0.0 0.18 11.7 0.0 2.0 1 1 1 2 2 2 0 Esterase-like activity of phytase EphA2_TM PF14575.6 GBG70799.1 - 0.079 13.9 0.0 1.9 9.4 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 GBG70799.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Nop14 PF04147.12 GBG70799.1 - 1.3 7.1 8.6 1.8 6.7 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family RPN2_C PF18004.1 GBG70799.1 - 1.8 8.4 6.5 3.2 7.6 6.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TFIIF_alpha PF05793.12 GBG70799.1 - 1.9 7.0 12.2 3.4 6.2 12.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RT_RNaseH_2 PF17919.1 GBG70800.1 - 1.5e-27 95.5 0.0 2.7e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70800.1 - 4.7e-24 84.7 0.0 9.1e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG70800.1 - 0.47 9.8 12.4 0.64 9.4 12.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG70800.1 - 0.54 8.5 11.4 0.78 8.0 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG70800.1 - 1.7 6.7 15.0 2.3 6.3 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF659 PF04937.15 GBG70801.1 - 3.4e-10 40.0 0.0 6.1e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4508 PF14969.6 GBG70801.1 - 0.1 12.8 0.0 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) Pkinase PF00069.25 GBG70803.1 - 2e-19 70.0 0.0 4.6e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70803.1 - 8.3e-19 67.9 0.0 1.5e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG70803.1 - 9.9e-10 38.9 3.4 2.9e-05 24.7 0.1 5.0 3 1 1 4 4 4 2 WD domain, G-beta repeat DUF1644 PF07800.12 GBG70803.1 - 0.0036 17.4 4.2 0.043 13.9 3.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1644) Kinesin PF00225.23 GBG70804.1 - 2e-106 355.7 0.2 3.8e-106 354.8 0.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG70804.1 - 3.6e-47 160.0 5.9 5.4e-47 159.5 0.0 2.9 3 0 0 3 3 3 1 Microtubule binding MyTH4 PF00784.17 GBG70804.1 - 1.3e-26 93.2 0.1 4.7e-26 91.4 0.1 2.1 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.18 GBG70804.1 - 1.4e-17 64.2 0.0 1.4e-17 64.2 0.0 2.7 2 1 0 2 2 1 1 FERM central domain FERM_N PF09379.10 GBG70804.1 - 1.2e-06 28.4 0.2 3.1e-06 27.0 0.2 1.8 1 0 0 1 1 1 1 FERM N-terminal domain Mce4_CUP1 PF11887.8 GBG70804.1 - 0.0041 16.6 1.3 0.0041 16.6 1.3 2.3 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF3426 PF11906.8 GBG70804.1 - 0.024 14.8 0.1 0.057 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) DUF3450 PF11932.8 GBG70804.1 - 0.065 12.5 40.3 0.17 11.2 9.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) HMMR_N PF15905.5 GBG70804.1 - 0.27 10.7 40.8 0.53 9.7 8.0 2.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 GBG70804.1 - 0.49 10.8 51.1 0.17 12.3 13.0 3.9 3 1 1 4 4 4 0 Fez1 DUF4795 PF16043.5 GBG70804.1 - 0.71 9.4 35.6 0.45 10.1 21.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Snapin_Pallidin PF14712.6 GBG70804.1 - 1.9 8.9 33.4 0.55 10.7 3.8 3.9 3 0 0 3 3 3 0 Snapin/Pallidin KASH_CCD PF14662.6 GBG70804.1 - 2.2 8.1 48.2 1.5 8.6 5.8 3.8 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 GBG70804.1 - 2.3 7.7 42.3 0.015 14.9 5.5 3.4 2 1 1 3 3 3 0 Intermediate filament protein Leu_zip PF15294.6 GBG70804.1 - 4 6.9 36.8 2.6 7.5 3.7 2.7 2 0 0 2 2 2 0 Leucine zipper Pkinase PF00069.25 GBG70808.1 - 8.5e-26 90.9 0.0 1.6e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70808.1 - 1.1e-23 83.9 0.0 2.1e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG70808.1 - 1.1e-11 45.1 2.2 1.8e-07 31.7 0.1 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG70808.1 - 0.0016 18.7 0.5 0.013 15.8 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG70808.1 - 0.0027 16.4 0.1 0.016 13.9 0.1 2.2 3 0 0 3 3 3 1 Nucleoporin Nup120/160 DUF1137 PF06587.11 GBG70808.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) TPP_enzyme_N PF02776.18 GBG70810.1 - 4.3e-52 176.2 0.1 1.1e-51 174.8 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GBG70810.1 - 1.2e-44 151.7 0.0 1e-43 148.8 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GBG70810.1 - 5.3e-43 146.1 0.0 3e-42 143.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain ECM1 PF05782.11 GBG70810.1 - 1 8.2 3.2 5.5 5.8 2.2 2.0 2 0 0 2 2 2 0 Extracellular matrix protein 1 (ECM1) Cwf_Cwc_15 PF04889.12 GBG70811.1 - 2.3 7.9 29.2 26 4.4 28.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Plasmodium_Vir PF05795.11 GBG70811.1 - 2.5 7.4 6.7 4 6.8 6.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TPP_enzyme_N PF02776.18 GBG70812.1 - 2.6e-52 176.9 0.1 5.7e-52 175.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GBG70812.1 - 3.2e-45 153.6 0.0 4.4e-44 149.9 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GBG70812.1 - 9.8e-45 151.7 0.0 8.6e-43 145.4 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 GBG70813.1 - 2.5e-52 176.9 0.1 6e-52 175.7 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GBG70813.1 - 2.5e-45 154.0 0.0 4.7e-44 149.9 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GBG70813.1 - 5.8e-45 152.4 0.0 4.9e-43 146.2 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain GLTT PF01744.20 GBG70813.1 - 0.00034 20.3 2.0 0.00034 20.3 2.0 2.6 3 0 0 3 3 3 1 GLTT repeat (6 copies) WD40 PF00400.32 GBG70814.1 - 8e-10 39.2 4.1 0.0019 19.0 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 GBG70814.1 - 0.00065 18.5 0.5 0.11 11.1 0.0 3.8 3 1 2 5 5 5 1 Nucleoporin Nup120/160 OsmC PF02566.19 GBG70814.1 - 2.9 8.4 5.2 0.93 10.0 0.8 2.2 1 1 1 2 2 2 0 OsmC-like protein RT_RNaseH_2 PF17919.1 GBG70815.1 - 1.2e-20 73.4 0.0 2e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70815.1 - 9.6e-20 70.8 0.0 1.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70815.1 - 4.7e-19 68.2 0.2 8.1e-19 67.5 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG70815.1 - 5.6e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70815.1 - 6.9e-08 33.0 0.0 1.3e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70815.1 - 3.3e-06 27.6 0.0 6.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG70815.1 - 0.0074 16.1 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG70815.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Importin_rep_4 PF18808.1 GBG70815.1 - 0.15 12.3 0.5 0.92 9.8 0.1 2.3 2 0 0 2 2 2 0 Importin repeat WD40 PF00400.32 GBG70816.1 - 0.00011 22.9 0.0 0.00031 21.5 0.0 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat HTH_Bact PF18768.1 GBG70816.1 - 0.075 12.6 1.6 16 5.1 0.9 3.3 3 0 0 3 3 3 0 Helix-turn-helix bacterial domain BLOC1_2 PF10046.9 GBG70816.1 - 0.58 10.5 21.3 3.8 7.9 0.4 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.12 GBG70816.1 - 3.1 7.3 36.4 0.12 11.9 25.6 2.3 2 0 0 2 2 2 0 PspA/IM30 family Ntox28 PF15605.6 GBG70816.1 - 7 7.0 12.6 3.2 8.0 1.5 3.2 2 1 0 3 3 3 0 Bacterial toxin 28 KxDL PF10241.9 GBG70816.1 - 8 6.8 8.3 3.6 7.9 1.2 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein zf-CCHC_4 PF14392.6 GBG70817.1 - 0.046 13.5 0.1 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG70817.1 - 0.13 12.4 0.6 0.31 11.2 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG70818.1 - 1.6e-17 63.8 0.0 2.4e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Glyco_transf_4 PF13439.6 GBG70819.1 - 8.6e-06 25.9 0.3 3.2e-05 24.0 0.3 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DUF2722 PF10846.8 GBG70819.1 - 0.00045 19.3 2.6 0.00097 18.2 2.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Glyco_trans_4_4 PF13579.6 GBG70819.1 - 0.00051 20.5 0.5 0.00051 20.5 0.5 2.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 GBG70819.1 - 0.00056 20.4 0.2 0.0016 18.9 0.2 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 MecA PF05389.12 GBG70819.1 - 0.029 14.0 1.7 0.046 13.4 0.2 2.0 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Med3 PF11593.8 GBG70819.1 - 0.11 11.6 9.1 0.16 11.1 9.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glycos_transf_1 PF00534.20 GBG70819.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Connexin PF00029.19 GBG70819.1 - 0.26 11.0 2.1 0.64 9.7 0.5 2.3 2 0 0 2 2 2 0 Connexin Neur_chan_memb PF02932.16 GBG70819.1 - 0.48 10.5 1.2 1.2 9.2 1.2 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 GBG70819.1 - 1.5 8.0 7.1 4.5 6.4 7.1 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 GBG70819.1 - 1.9 7.9 26.7 0.021 14.2 17.6 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region BAF250_C PF12031.8 GBG70819.1 - 2.2 7.5 5.0 1.5 8.0 2.3 2.0 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa eIF_4EBP PF05456.11 GBG70819.1 - 5 7.1 6.2 16 5.5 6.2 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) UPF0560 PF10577.9 GBG70819.1 - 5.1 5.5 12.1 8.6 4.7 12.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pex14_N PF04695.13 GBG70819.1 - 5.8 7.6 8.5 12 6.5 8.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cytomega_UL84 PF06284.11 GBG70819.1 - 8.2 4.8 5.9 8.9 4.6 0.0 2.9 3 0 0 3 3 3 0 Cytomegalovirus UL84 protein Myb_DNA-bind_4 PF13837.6 GBG70820.1 - 7.9e-07 29.4 1.6 1.7e-06 28.3 1.6 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG70820.1 - 8.2e-05 22.6 1.4 0.00015 21.8 1.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG70820.1 - 0.3 11.3 2.1 0.45 10.7 0.6 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG70821.1 - 1.8e-33 114.5 0.1 4e-33 113.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70821.1 - 1.2e-30 105.9 0.4 3.3e-30 104.5 0.4 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70821.1 - 2.2e-12 47.0 0.2 4.6e-12 45.9 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG70822.1 - 1.6e-23 83.4 0.0 3.5e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70822.1 - 2.7e-18 66.2 0.0 6.1e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG70822.1 - 6.3e-10 39.5 4.1 0.0012 19.7 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 GBG70822.1 - 0.021 13.5 0.0 5.7 5.5 0.0 3.0 2 1 0 3 3 3 0 Nucleoporin Nup120/160 IPK PF03770.16 GBG70822.1 - 0.072 12.9 0.3 0.19 11.5 0.3 1.7 1 0 0 1 1 1 0 Inositol polyphosphate kinase KxDL PF10241.9 GBG70822.1 - 1.7 8.9 7.0 8.3 6.8 0.7 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein Prominin PF05478.11 GBG70822.1 - 6.4 4.6 16.7 0.02 12.9 2.1 2.6 1 1 2 3 3 3 0 Prominin RT_RNaseH PF17917.1 GBG70824.1 - 4.4e-23 81.6 0.0 6.8e-22 77.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70824.1 - 7.5e-22 77.3 0.0 4.9e-21 74.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70824.1 - 3.9e-09 36.4 0.0 7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG70825.1 - 0.15 11.8 0.1 0.65 9.6 0.1 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease Pkinase PF00069.25 GBG70827.1 - 1.6e-23 83.5 0.0 3.3e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70827.1 - 1.9e-19 70.0 0.0 4.4e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG70827.1 - 6.3e-08 33.2 0.8 0.0023 18.7 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Prominin PF05478.11 GBG70827.1 - 0.0015 16.6 2.9 0.0015 16.6 2.9 3.0 1 1 1 3 3 3 1 Prominin ANAPC4_WD40 PF12894.7 GBG70827.1 - 0.0064 16.8 0.0 0.3 11.4 0.0 3.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain KxDL PF10241.9 GBG70827.1 - 0.085 13.1 7.0 3.8 7.9 0.8 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein HTH_Bact PF18768.1 GBG70827.1 - 0.43 10.2 5.3 55 3.5 1.0 4.2 4 0 0 4 4 4 0 Helix-turn-helix bacterial domain Coatomer_g_Cpla PF16381.5 GBG70827.1 - 0.57 10.3 3.1 19 5.4 0.1 3.4 3 0 0 3 3 3 0 Coatomer subunit gamma-1 C-terminal appendage platform STAT_alpha PF01017.20 GBG70827.1 - 0.82 9.5 25.0 0.58 10.0 5.2 3.1 2 1 1 3 3 3 0 STAT protein, all-alpha domain CLZ PF16526.5 GBG70827.1 - 2.2 8.7 35.6 1.3 9.5 1.5 5.4 3 3 3 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mit_KHE1 PF10173.9 GBG70827.1 - 9.7 6.2 6.6 0.75 9.8 0.5 2.2 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related WD40 PF00400.32 GBG70828.1 - 1.2e-09 38.6 0.5 0.00063 20.5 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Prominin PF05478.11 GBG70828.1 - 0.0036 15.3 9.1 0.093 10.7 2.5 2.1 1 1 1 2 2 2 2 Prominin Nup160 PF11715.8 GBG70828.1 - 0.01 14.5 0.0 0.91 8.1 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Cep57_MT_bd PF06657.13 GBG70828.1 - 0.13 12.8 15.6 3.5 8.2 0.7 3.8 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF842 PF05811.13 GBG70828.1 - 0.15 11.7 5.7 0.25 11.0 5.7 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Pkinase PF00069.25 GBG70829.1 - 7.9e-07 28.7 0.0 8.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70829.1 - 1.2e-05 24.8 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Lactamase_B PF00753.27 GBG70831.1 - 2.2e-08 34.3 2.2 2.3e-07 31.0 2.2 2.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF659 PF04937.15 GBG70832.1 - 3.8e-10 39.8 0.0 6.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG70833.1 - 1.8e-25 88.9 0.0 4.3e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70833.1 - 5.1e-24 84.6 0.0 1.2e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG70833.1 - 1.1e-07 32.4 0.0 3.9e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70833.1 - 1.1e-07 32.3 0.0 2.7e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG70833.1 - 9.5e-06 25.4 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG70833.1 - 4.1e-05 23.3 0.0 7.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG70833.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG70833.1 - 0.013 15.8 0.4 2.4 8.5 0.0 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG70834.1 - 2.4e-28 98.5 0.2 1.5e-27 96.0 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70834.1 - 2.7e-28 99.0 0.1 5.3e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG70834.1 - 3.3e-22 79.0 0.0 9.4e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG70834.1 - 7.6e-22 77.9 0.6 5.3e-21 75.2 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG70834.1 - 2.5e-21 75.6 0.2 3.7e-20 71.8 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70834.1 - 3.1e-18 65.6 0.2 8.1e-18 64.3 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70834.1 - 7.9e-15 55.1 0.0 2.2e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain WD40 PF00400.32 GBG70834.1 - 2.7e-09 37.5 2.4 0.0027 18.5 0.0 4.2 4 0 0 4 4 3 2 WD domain, G-beta repeat gag-asp_proteas PF13975.6 GBG70834.1 - 4.7e-06 27.1 0.0 1.4e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70834.1 - 0.00062 20.4 0.0 0.0017 18.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Nup160 PF11715.8 GBG70834.1 - 0.0023 16.7 1.9 1.8 7.1 0.0 3.9 4 1 0 5 5 5 1 Nucleoporin Nup120/160 zf-H2C2 PF09337.10 GBG70834.1 - 0.0067 16.6 0.0 0.023 14.9 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG70834.1 - 0.036 13.8 0.0 0.093 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative peptidase (DUF1758) ANAPC4_WD40 PF12894.7 GBG70834.1 - 0.1 12.9 0.1 1.5 9.1 0.0 2.6 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1564 PF07600.11 GBG70834.1 - 0.11 12.2 0.5 0.28 10.9 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1564) GvpK PF05121.12 GBG70834.1 - 0.27 11.3 5.9 0.54 10.3 4.5 2.4 2 0 0 2 2 1 0 Gas vesicle protein K Sec20 PF03908.13 GBG70834.1 - 0.32 10.9 6.0 0.58 10.1 4.0 2.5 2 0 0 2 2 1 0 Sec20 UPF0242 PF06785.11 GBG70834.1 - 1 9.4 15.3 2.7 8.0 15.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 GBG70834.1 - 1.1 8.8 9.9 2.7 7.5 9.9 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit CAF1 PF04857.20 GBG70834.1 - 1.2 8.2 3.5 2.8 7.0 3.5 1.5 1 0 0 1 1 1 0 CAF1 family ribonuclease FUSC PF04632.12 GBG70834.1 - 1.3 7.5 6.4 2.3 6.7 6.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GPO PF05929.11 GBG70834.1 - 1.6 8.2 8.9 3.8 7.1 8.9 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 GBG70834.1 - 1.7 7.9 8.8 10 5.4 9.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 GBG70834.1 - 2.4 6.6 15.6 3.6 6.0 15.6 1.2 1 0 0 1 1 1 0 Macoilin family Atg14 PF10186.9 GBG70834.1 - 2.4 7.1 12.0 5.4 6.0 12.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4800 PF16057.5 GBG70834.1 - 2.5 7.3 9.2 2.3 7.4 6.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) Spc7 PF08317.11 GBG70834.1 - 3.1 6.6 19.0 7.7 5.3 19.0 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 GBG70834.1 - 3.3 7.8 12.4 1.6 8.8 8.0 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 GBG70834.1 - 6 6.0 9.6 18 4.4 9.3 2.0 2 0 0 2 2 2 0 TMPIT-like protein Fer4_24 PF18109.1 GBG70834.1 - 7.1 7.0 8.0 1.8 8.9 3.3 2.2 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain RT_RNaseH_2 PF17919.1 GBG70835.1 - 2.2e-26 91.8 0.0 5.5e-26 90.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70835.1 - 5.9e-25 87.6 0.0 1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG70835.1 - 0.0093 15.9 0.3 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 GBG70836.1 - 0.028 14.5 3.4 0.028 14.5 3.4 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CHC2 PF01807.20 GBG70836.1 - 0.16 11.8 0.1 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 CHC2 zinc finger CDC45 PF02724.14 GBG70836.1 - 0.95 7.7 2.9 1.2 7.3 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.8 GBG70836.1 - 2.4 9.2 9.3 5.2 8.1 9.3 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Dimer_Tnp_hAT PF05699.14 GBG70837.1 - 1.3e-05 24.9 0.1 2.4e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2746 PF10874.8 GBG70837.1 - 0.076 13.4 0.1 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) TPP_enzyme_N PF02776.18 GBG70838.1 - 6.7e-52 175.6 0.0 1.1e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GBG70838.1 - 2.1e-12 47.0 0.0 4.7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain PTPS PF01242.19 GBG70838.1 - 0.14 12.1 0.1 0.41 10.6 0.1 1.8 1 1 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase DUF1729 PF08354.10 GBG70838.1 - 0.16 10.8 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) zf-CCHC PF00098.23 GBG70838.1 - 0.38 10.9 5.0 0.68 10.1 5.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Atrophin-1 PF03154.15 GBG70839.1 - 1 7.5 12.6 2 6.6 12.6 1.4 1 0 0 1 1 1 0 Atrophin-1 family Pkinase PF00069.25 GBG70840.1 - 2.8e-19 69.5 0.2 4.7e-18 65.5 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70840.1 - 1.7e-18 66.9 0.4 1.1e-16 60.9 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.32 GBG70840.1 - 3.1e-08 34.1 4.1 0.038 14.9 0.1 4.3 4 0 0 4 4 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG70840.1 - 0.0025 18.1 1.5 0.49 10.7 0.0 4.0 3 1 0 3 3 2 1 Anaphase-promoting complex subunit 4 WD40 domain GAS PF13851.6 GBG70840.1 - 0.003 16.9 14.6 0.0063 15.9 14.6 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 GBG70840.1 - 0.0074 15.2 15.8 0.012 14.5 15.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Sec20 PF03908.13 GBG70840.1 - 0.0092 15.9 6.6 0.041 13.8 5.7 2.3 2 0 0 2 2 2 1 Sec20 Macoilin PF09726.9 GBG70840.1 - 0.0097 14.5 16.5 0.013 14.1 16.5 1.1 1 0 0 1 1 1 1 Macoilin family RPW8 PF05659.11 GBG70840.1 - 0.018 14.7 2.8 0.037 13.7 2.8 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TPR_MLP1_2 PF07926.12 GBG70840.1 - 0.019 15.0 17.9 0.046 13.8 17.9 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 GBG70840.1 - 0.023 14.3 8.4 0.041 13.5 8.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 GBG70840.1 - 0.024 14.9 4.6 0.027 14.8 2.9 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 GBG70840.1 - 0.045 13.8 2.0 0.11 12.6 0.9 2.3 1 1 1 2 2 2 0 bZIP transcription factor Nup160 PF11715.8 GBG70840.1 - 0.099 11.3 3.3 4.6 5.8 0.2 3.4 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Atg14 PF10186.9 GBG70840.1 - 0.1 11.7 10.3 0.17 10.9 10.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 GBG70840.1 - 0.28 10.0 20.0 0.56 9.0 20.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 GBG70840.1 - 0.9 9.8 4.3 2.5 8.4 4.2 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Phage_GPO PF05929.11 GBG70840.1 - 0.95 9.0 12.4 1.6 8.3 12.4 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FUSC PF04632.12 GBG70840.1 - 1.1 7.7 6.9 1.5 7.3 6.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family COG5 PF10392.9 GBG70840.1 - 1.3 9.2 6.0 22 5.2 5.6 2.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 ABC_tran_CTD PF16326.5 GBG70840.1 - 1.5 9.1 10.1 0.089 13.0 1.5 2.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain UPF0242 PF06785.11 GBG70840.1 - 2.6 8.1 16.3 6 6.9 16.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 GBG70840.1 - 2.9 6.4 15.6 4.1 5.9 15.6 1.1 1 0 0 1 1 1 0 AAA domain LPP PF04728.13 GBG70840.1 - 3.3 8.2 5.3 5.7 7.4 0.3 3.3 2 1 1 3 3 3 0 Lipoprotein leucine-zipper 5_nucleotid PF05761.14 GBG70840.1 - 3.3 6.5 9.7 4.8 6.0 8.7 1.7 2 0 0 2 2 2 0 5' nucleotidase family Ead_Ea22 PF13935.6 GBG70840.1 - 3.4 8.3 10.2 5.6 7.6 9.7 1.7 1 1 0 1 1 1 0 Ead/Ea22-like protein DUF848 PF05852.11 GBG70840.1 - 4.6 7.4 13.3 2.8 8.0 10.7 2.1 2 1 1 3 3 2 0 Gammaherpesvirus protein of unknown function (DUF848) Occludin_ELL PF07303.13 GBG70840.1 - 5.2 7.9 8.9 2 9.2 3.2 2.2 1 1 2 3 3 3 0 Occludin homology domain Tho2 PF11262.8 GBG70840.1 - 5.9 6.0 9.3 8.6 5.5 8.5 1.6 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spc24 PF08286.11 GBG70840.1 - 6.6 7.0 9.9 1.8 8.8 4.9 2.5 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 GBG70840.1 - 6.8 6.7 16.0 12 6.0 7.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4094 PF13334.6 GBG70840.1 - 7 7.1 7.4 40 4.7 7.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Cob_adeno_trans PF01923.18 GBG70840.1 - 7.1 6.7 8.3 23 5.1 8.3 2.0 1 1 0 1 1 1 0 Cobalamin adenosyltransferase DUF4407 PF14362.6 GBG70840.1 - 7.3 5.8 13.0 2.5 7.4 10.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cep57_MT_bd PF06657.13 GBG70840.1 - 7.4 7.1 13.0 0.71 10.4 6.6 2.5 2 1 1 3 3 2 0 Centrosome microtubule-binding domain of Cep57 HemX PF04375.14 GBG70840.1 - 8 5.6 14.0 8.2 5.6 12.9 1.6 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DLP_helical PF18709.1 GBG70840.1 - 9.3 5.3 16.9 0.64 9.2 5.1 2.3 1 1 1 2 2 2 0 Dynamin-like helical domain Sec20 PF03908.13 GBG70841.1 - 0.0029 17.5 2.1 0.0029 17.5 2.1 2.9 1 1 2 3 3 3 2 Sec20 Macoilin PF09726.9 GBG70841.1 - 0.0049 15.5 23.0 0.0058 15.3 23.0 1.0 1 0 0 1 1 1 1 Macoilin family DUF812 PF05667.11 GBG70841.1 - 0.012 14.6 27.9 0.015 14.2 27.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 GBG70841.1 - 0.019 14.5 22.5 0.014 15.0 18.6 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit YPEB PF14620.6 GBG70841.1 - 1.2 8.4 18.2 0.67 9.2 3.1 2.7 1 1 2 3 3 3 0 YpeB sporulation Vac_Fusion PF02346.16 GBG70841.1 - 1.7 8.3 12.3 3.4 7.4 1.0 3.7 4 1 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 DUF1848 PF08902.11 GBG70841.1 - 1.8 8.2 13.8 0.082 12.6 3.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1848) TMPIT PF07851.13 GBG70841.1 - 2.3 7.4 21.6 0.042 13.1 12.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 GBG70841.1 - 2.6 7.3 16.6 4.5 6.5 16.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 GBG70841.1 - 3.2 7.9 22.1 0.47 10.6 13.3 2.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Cep57_CLD PF14073.6 GBG70841.1 - 3.2 7.7 34.7 0.64 10.0 9.5 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 SlyX PF04102.12 GBG70841.1 - 3.4 8.3 19.9 1.4 9.6 3.2 3.2 2 1 1 3 3 3 0 SlyX Filo_VP35 PF02097.15 GBG70841.1 - 4 6.4 9.6 4.1 6.4 2.4 2.5 1 1 2 3 3 3 0 Filoviridae VP35 DUF2730 PF10805.8 GBG70841.1 - 4.1 7.6 13.4 0.6 10.2 1.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) GAS PF13851.6 GBG70841.1 - 5 6.4 28.9 3 7.1 22.9 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 GBG70841.1 - 5.1 6.1 22.1 7.1 5.6 15.9 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Snapin_Pallidin PF14712.6 GBG70841.1 - 5.3 7.5 25.5 10 6.6 6.6 2.4 1 1 1 2 2 2 0 Snapin/Pallidin MEA1 PF06910.11 GBG70842.1 - 5.1e-05 23.9 0.9 5.1e-05 23.9 0.9 2.4 2 0 0 2 2 2 1 Male enhanced antigen 1 (MEA1) CDC45 PF02724.14 GBG70842.1 - 3.1 6.0 13.6 0.46 8.7 5.6 2.1 2 0 0 2 2 2 0 CDC45-like protein NOA36 PF06524.12 GBG70842.1 - 3.6 6.8 15.7 1.5 8.0 8.1 2.2 2 0 0 2 2 2 0 NOA36 protein Pkinase PF00069.25 GBG70843.1 - 8.4e-21 74.5 0.2 3.4e-20 72.5 0.0 2.1 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70843.1 - 6.9e-18 64.9 0.3 2.7e-17 62.9 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.32 GBG70843.1 - 2.7e-12 47.0 2.2 0.00017 22.3 0.0 4.4 4 0 0 4 4 3 3 WD domain, G-beta repeat Nup160 PF11715.8 GBG70843.1 - 1.3e-06 27.3 0.2 0.032 12.9 0.0 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GBG70843.1 - 0.035 14.4 0.1 0.8 10.0 0.1 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Exonuc_VII_L PF02601.15 GBG70843.1 - 0.059 12.9 24.5 0.014 15.0 17.9 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Sec20 PF03908.13 GBG70843.1 - 0.13 12.2 10.3 0.22 11.5 4.6 2.9 1 1 2 3 3 3 0 Sec20 TMPIT PF07851.13 GBG70843.1 - 0.46 9.7 18.2 0.29 10.4 13.4 2.6 2 1 1 3 3 3 0 TMPIT-like protein Vac_Fusion PF02346.16 GBG70843.1 - 1.5 8.5 8.1 6.4 6.5 0.8 3.2 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF2730 PF10805.8 GBG70843.1 - 2 8.5 9.8 0.51 10.5 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 GBG70843.1 - 2.9 7.2 17.8 4.9 6.4 17.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 GBG70843.1 - 5.5 4.8 21.0 0.81 7.5 16.9 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L28 PF00830.19 GBG70845.1 - 2.4e-14 53.3 1.0 3e-14 52.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L28 family Tam41_Mmp37 PF09139.11 GBG70846.1 - 1.8e-22 80.2 0.0 2e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial RVP_2 PF08284.11 GBG70846.1 - 2.4e-08 33.8 0.0 3.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG70846.1 - 8.5e-05 22.3 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG70846.1 - 0.00071 20.2 0.1 0.0019 18.8 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70846.1 - 0.0045 17.5 0.0 0.014 16.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG70848.1 - 2.8e-09 36.6 0.1 5.1e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LAP1C PF05609.12 GBG70849.1 - 2 7.4 18.8 2.7 7.0 18.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PA26 PF04636.13 GBG70849.1 - 6.8 5.5 23.2 0.076 11.9 11.3 2.1 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) DUF3138 PF11336.8 GBG70849.1 - 8.3 4.9 5.3 1.5 7.4 1.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) RVT_1 PF00078.27 GBG70850.1 - 7.2e-35 120.5 0.1 1.3e-34 119.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70850.1 - 1.4e-30 105.3 0.0 4.9e-30 103.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70850.1 - 4.8e-30 103.9 0.1 1e-29 102.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG70850.1 - 1.3e-07 31.5 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70850.1 - 1.1e-05 26.0 0.0 2.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70850.1 - 0.0033 17.9 0.0 0.011 16.3 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG70850.1 - 0.0041 16.9 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG70850.1 - 0.028 14.0 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Asp_protease PF09668.10 GBG70850.1 - 0.042 13.6 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease Sirohm_synth_M PF14824.6 GBG70850.1 - 0.16 11.5 0.0 0.43 10.1 0.0 1.8 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central DUF4392 PF14336.6 GBG70850.1 - 0.23 10.9 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Glyco_tranf_2_3 PF13641.6 GBG70851.1 - 7e-34 117.7 0.0 1.1e-33 117.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GBG70851.1 - 1.3e-25 90.2 0.0 1.9e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 GBG70851.1 - 4e-21 75.8 2.9 4e-21 75.8 2.9 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 GBG70851.1 - 1.3e-18 66.9 0.7 1.5e-09 36.9 0.3 3.0 1 1 2 3 3 3 3 Cellulose synthase Glyco_transf_21 PF13506.6 GBG70851.1 - 5.5e-13 48.8 0.0 9.2e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 GBG70851.1 - 0.029 14.9 0.1 0.071 13.6 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 Integrase_H2C2 PF17921.1 GBG70852.1 - 2.7e-15 56.2 0.1 5.3e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70852.1 - 3.1e-07 30.6 0.0 5.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70852.1 - 0.0016 18.6 0.0 0.004 17.3 0.0 1.7 2 0 0 2 2 2 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG70853.1 - 1.1e-28 99.2 0.0 1.9e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70853.1 - 1.1e-23 83.5 0.0 1.8e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70853.1 - 2.1e-08 34.0 0.2 4e-08 33.1 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG70853.1 - 0.011 15.2 22.3 0.015 14.7 22.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG70853.1 - 0.018 13.3 23.1 0.027 12.7 23.1 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG70853.1 - 0.28 9.9 1.7 0.36 9.5 1.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 GBG70853.1 - 0.36 9.2 22.7 0.66 8.4 22.7 1.3 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 GBG70853.1 - 2.1 6.8 32.5 3.1 6.3 32.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GBG70853.1 - 5.5 5.1 20.5 8.6 4.5 20.5 1.3 1 0 0 1 1 1 0 CDC45-like protein GCN5L1 PF06320.13 GBG70854.1 - 0.056 13.6 3.4 0.13 12.5 3.4 1.6 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Salt_tol_Pase PF09506.10 GBG70854.1 - 0.12 11.2 0.4 0.18 10.5 0.4 1.2 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) YabA PF06156.13 GBG70854.1 - 0.14 12.8 2.7 0.41 11.3 0.0 3.0 4 0 0 4 4 4 0 Initiation control protein YabA Med3 PF11593.8 GBG70854.1 - 0.23 10.6 2.8 0.36 10.0 2.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NMD3 PF04981.13 GBG70854.1 - 0.3 10.5 3.3 8.5 5.8 0.2 2.4 2 0 0 2 2 2 0 NMD3 family Nop14 PF04147.12 GBG70854.1 - 4 5.5 18.5 4.1 5.5 11.3 2.1 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.12 GBG70854.1 - 6.8 5.9 11.3 14 4.9 11.3 1.4 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 GBG70855.1 - 0.0014 18.3 17.8 0.004 16.8 17.8 1.7 1 0 0 1 1 1 1 PPP4R2 Zmiz1_N PF18028.1 GBG70855.1 - 0.078 13.3 0.0 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain CDC45 PF02724.14 GBG70855.1 - 0.12 10.7 11.4 0.18 10.0 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Rhabdo_ncap PF00945.18 GBG70855.1 - 0.14 11.1 5.0 0.033 13.1 1.8 1.6 1 1 0 1 1 1 0 Rhabdovirus nucleocapsid protein Nop14 PF04147.12 GBG70855.1 - 0.42 8.8 18.7 0.63 8.2 18.7 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 GBG70855.1 - 1.5 8.7 18.9 2.5 8.0 18.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 GBG70855.1 - 4.4 6.5 15.0 7.2 5.8 15.0 1.4 1 0 0 1 1 1 0 BUD22 Herpes_LMP1 PF05297.11 GBG70855.1 - 9.1 5.4 15.6 13 4.8 15.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3987 PF13148.6 GBG70856.1 - 0.0033 16.5 1.8 0.0033 16.5 1.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) PI3K_1B_p101 PF10486.9 GBG70856.1 - 0.15 9.8 5.8 0.14 9.9 5.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4718 PF15842.5 GBG70856.1 - 0.58 9.9 2.8 0.96 9.2 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Ferritin PF00210.24 GBG70856.1 - 1.1 9.2 6.7 0.074 13.0 1.1 1.9 2 1 0 2 2 2 0 Ferritin-like domain DUF4407 PF14362.6 GBG70856.1 - 3.9 6.7 10.2 5.8 6.2 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_tranf_2_3 PF13641.6 GBG70857.1 - 8.2e-34 117.5 0.0 1.1e-33 117.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GBG70857.1 - 1e-25 90.5 0.0 1.5e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 GBG70857.1 - 3e-19 69.7 2.2 1.5e-18 67.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 GBG70857.1 - 1.6e-13 50.5 0.0 2.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 GBG70857.1 - 1.4e-11 43.7 0.1 0.00049 18.7 0.0 3.1 1 1 2 3 3 3 3 Cellulose synthase Glyco_tranf_2_4 PF13704.6 GBG70857.1 - 0.019 15.5 0.1 0.044 14.3 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG70860.1 - 7.1e-34 117.7 0.0 1.1e-33 117.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GBG70860.1 - 6.4e-25 87.9 0.0 9.7e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 GBG70860.1 - 1.8e-21 77.0 2.3 1.8e-21 77.0 2.3 2.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 GBG70860.1 - 1.4e-17 63.6 0.4 6.4e-09 34.9 0.2 3.0 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 GBG70860.1 - 5.3e-13 48.8 0.0 9.3e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 GBG70860.1 - 0.14 12.7 0.4 0.36 11.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 MPLKIP PF15502.6 GBG70861.1 - 0.026 14.7 0.4 0.064 13.5 0.4 1.7 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein RVT_1 PF00078.27 GBG70862.1 - 1.1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIF_alpha PF05793.12 GBG70862.1 - 0.14 10.7 13.1 0.17 10.4 13.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4746 PF15928.5 GBG70862.1 - 0.41 10.0 12.3 0.57 9.6 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 GBG70862.1 - 1.3 8.4 13.4 1.6 8.1 13.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG70862.1 - 3 5.9 15.4 3.7 5.7 15.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF659 PF04937.15 GBG70863.1 - 2.7e-24 85.7 0.2 5.6e-24 84.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG70863.1 - 4e-05 23.3 0.1 4e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DDE_Tnp_4 PF13359.6 GBG70864.1 - 8.2e-30 103.6 0.0 1.3e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70864.1 - 7.2e-11 42.1 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG70864.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG70864.1 - 0.16 11.6 0.0 8.3 6.0 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain BUD22 PF09073.10 GBG70865.1 - 0.00053 19.5 8.7 0.00053 19.5 8.7 1.9 3 0 0 3 3 3 1 BUD22 Tim54 PF11711.8 GBG70865.1 - 0.022 13.6 4.1 0.035 12.9 4.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 GBG70865.1 - 0.92 8.2 2.4 1.4 7.6 2.4 1.2 1 0 0 1 1 1 0 Presenilin Mpp10 PF04006.12 GBG70865.1 - 1.9 6.9 21.3 2.9 6.2 21.3 1.2 1 0 0 1 1 1 0 Mpp10 protein Vfa1 PF08432.10 GBG70865.1 - 2 8.7 11.7 3.8 7.8 11.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_phi PF04931.13 GBG70865.1 - 3.4 5.6 28.6 6.9 4.6 28.6 1.4 1 0 0 1 1 1 0 DNA polymerase phi RT_RNaseH_2 PF17919.1 GBG70866.1 - 1.3e-31 108.6 0.0 4.5e-31 106.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70866.1 - 7.1e-30 103.4 0.0 1.7e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70866.1 - 2.2e-18 66.1 0.6 5.9e-18 64.7 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70866.1 - 0.00027 21.1 0.0 0.0011 19.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG70866.1 - 0.00075 19.1 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_lysozyme PF00959.19 GBG70866.1 - 0.031 14.7 0.1 0.21 12.0 0.0 2.5 2 0 0 2 2 2 0 Phage lysozyme zf-H2C2 PF09337.10 GBG70866.1 - 0.044 14.0 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Pox_Ag35 PF03286.14 GBG70866.1 - 0.26 11.0 18.1 1.6 8.5 15.0 2.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SbcD_C PF12320.8 GBG70866.1 - 0.51 10.7 0.0 0.51 10.7 0.0 3.6 4 0 0 4 4 4 0 Type 5 capsule protein repressor C-terminal domain SNF2_N PF00176.23 GBG70867.1 - 5.6e-51 173.3 0.0 7.9e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG70867.1 - 1.9e-18 66.9 0.0 3.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG70867.1 - 6.2e-05 23.1 0.0 0.00096 19.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG70867.1 - 0.00011 22.1 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GBG70867.1 - 0.00029 20.2 0.0 0.00049 19.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Period_C PF12114.8 GBG70868.1 - 1.3 8.5 7.0 1.6 8.3 7.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RT_RNaseH_2 PF17919.1 GBG70869.1 - 1.3e-25 89.3 0.0 2.5e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70869.1 - 3e-25 88.5 0.0 5.6e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70869.1 - 2.9e-10 40.0 0.0 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG70869.1 - 0.097 12.6 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Myb_DNA-bind_4 PF13837.6 GBG70870.1 - 0.013 15.9 0.7 0.026 14.9 0.7 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG70871.1 - 2.8e-27 95.3 0.0 1.7e-26 92.7 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70871.1 - 5.5e-12 45.7 0.0 9.8e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70871.1 - 0.0016 18.1 1.3 0.14 11.8 0.0 2.7 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG70871.1 - 0.042 14.2 0.8 0.7 10.3 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG70872.1 - 6.4e-29 99.9 0.0 1.8e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70872.1 - 7e-29 100.9 0.0 1.1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70872.1 - 1.3e-19 70.4 0.0 2.8e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG70872.1 - 1.1e-12 47.6 0.0 2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3080 PF11279.8 GBG70873.1 - 0.19 10.9 0.2 0.28 10.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Retrotrans_gag PF03732.17 GBG70874.1 - 0.0029 17.8 0.9 0.016 15.5 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein PAN_4 PF14295.6 GBG70874.1 - 0.49 10.3 6.2 1.4 8.9 6.2 1.7 1 0 0 1 1 1 0 PAN domain RT_RNaseH_2 PF17919.1 GBG70875.1 - 2e-26 91.9 0.0 4.7e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70875.1 - 1.1e-25 89.9 0.0 2.3e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70875.1 - 4.1e-17 62.0 0.1 8.3e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG70875.1 - 0.00088 19.5 0.8 0.0031 17.8 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG70875.1 - 0.0034 18.0 0.0 0.0089 16.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70875.1 - 0.0039 17.7 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG70875.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG70875.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease MULE PF10551.9 GBG70876.1 - 4.3e-14 52.7 0.0 9.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 GBG70876.1 - 0.00035 19.6 0.1 0.00074 18.5 0.1 1.4 1 0 0 1 1 1 1 Transposase, Mutator family RVT_1 PF00078.27 GBG70877.1 - 3.9e-32 111.6 0.0 3.5e-18 65.9 0.0 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70877.1 - 1.5e-28 98.7 0.0 2.8e-26 91.5 0.0 2.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70877.1 - 1.9e-26 92.4 0.0 1.3e-25 89.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70877.1 - 1.1e-18 67.1 0.4 1.1e-18 67.1 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG70877.1 - 5e-08 33.1 0.3 1.8e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG70877.1 - 2.7e-07 30.4 0.0 7.7e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG70877.1 - 8.7e-05 23.1 0.1 0.00059 20.4 0.1 2.3 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70877.1 - 0.00019 22.0 0.1 0.00065 20.2 0.0 2.0 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG70877.1 - 0.00033 20.5 0.0 0.00091 19.1 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG70877.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG70877.1 - 0.064 13.5 0.0 0.33 11.2 0.0 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein Paf1 PF03985.13 GBG70877.1 - 1.8 7.5 25.6 3.8 6.4 25.6 1.4 1 0 0 1 1 1 0 Paf1 PAN_4 PF14295.6 GBG70878.1 - 0.069 13.1 6.1 0.13 12.1 6.1 1.5 1 0 0 1 1 1 0 PAN domain PNMA PF14893.6 GBG70880.1 - 0.0078 15.7 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 PNMA Retrotrans_gag PF03732.17 GBG70880.1 - 0.069 13.4 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF659 PF04937.15 GBG70881.1 - 4.9e-15 55.7 0.0 7.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG70881.1 - 0.0041 16.9 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG70882.1 - 5.9e-31 106.5 0.0 2.1e-30 104.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70882.1 - 8.9e-31 106.3 0.1 2.8e-30 104.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70882.1 - 7.6e-14 51.6 0.1 1.9e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG70882.1 - 4.6e-13 49.2 0.0 9.4e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG70882.1 - 0.075 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger PAF-AH_p_II PF03403.13 GBG70882.1 - 4.6 5.7 5.5 8.1 4.8 5.5 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DDE_Tnp_4 PF13359.6 GBG70883.1 - 7.5e-26 90.7 0.0 1.1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70883.1 - 4e-16 59.2 0.0 5.8e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70883.1 - 0.00088 19.0 2.9 0.2 11.3 1.1 2.5 2 1 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG70884.1 - 3.3e-05 24.2 0.9 3.3e-05 24.2 0.9 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG70884.1 - 0.0013 18.8 0.5 0.0026 17.8 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain XhlA PF10779.9 GBG70885.1 - 0.058 13.6 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Haemolysin XhlA DASH_Hsk3 PF08227.11 GBG70885.1 - 0.083 13.3 4.1 4.7 7.7 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like PAN_4 PF14295.6 GBG70885.1 - 0.93 9.5 10.1 0.05 13.5 4.3 1.9 2 0 0 2 2 2 0 PAN domain Dimer_Tnp_hAT PF05699.14 GBG70887.1 - 1e-08 34.8 0.1 1e-08 34.8 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4682 PF15733.5 GBG70887.1 - 8.5 7.0 12.8 3.8 8.1 1.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4682) DUF659 PF04937.15 GBG70888.1 - 1.4e-07 31.5 0.0 2.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-FCS PF06467.14 GBG70888.1 - 0.25 11.3 1.9 0.52 10.3 1.9 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif PQQ_3 PF13570.6 GBG70889.1 - 8.3e-06 26.1 0.1 0.3 11.6 0.0 4.0 3 0 0 3 3 3 2 PQQ-like domain SGL PF08450.12 GBG70889.1 - 0.088 12.4 0.0 32 4.0 0.0 3.6 4 0 0 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 GBG70891.1 - 0.017 15.6 0.4 0.93 10.1 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain SGL PF08450.12 GBG70891.1 - 0.028 14.0 0.0 7 6.1 0.0 3.0 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 GBG70891.1 - 0.037 14.0 2.1 16 5.6 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 GBG70893.1 - 3.3e-05 24.2 0.2 0.078 13.5 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain SGL PF08450.12 GBG70893.1 - 0.014 15.0 0.0 5.7 6.5 0.0 3.2 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Cytochrom_D1 PF02239.16 GBG70893.1 - 0.12 10.9 0.0 0.21 10.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain TIM PF00121.18 GBG70894.1 - 5.9e-15 55.3 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Triosephosphate isomerase SDA1 PF05285.12 GBG70894.1 - 2.9e-06 27.0 14.2 3.2e-06 26.8 14.2 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG70894.1 - 4.2e-05 22.0 17.8 5.4e-05 21.7 17.8 1.1 1 0 0 1 1 1 1 Nop14-like family RVT_1 PF00078.27 GBG70894.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2052 PF09747.9 GBG70894.1 - 0.00052 20.2 18.9 0.0007 19.8 18.9 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 GBG70894.1 - 0.0013 17.2 18.2 0.0016 16.8 18.2 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 GBG70894.1 - 0.0017 17.8 14.4 0.0021 17.5 14.4 1.1 1 0 0 1 1 1 1 BUD22 HVSL PF09749.9 GBG70894.1 - 0.0064 16.0 1.5 0.011 15.2 1.5 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein DDHD PF02862.17 GBG70894.1 - 0.0079 16.4 1.7 0.0098 16.1 1.7 1.2 1 0 0 1 1 1 1 DDHD domain Mpp10 PF04006.12 GBG70894.1 - 0.011 14.2 23.5 0.015 13.8 23.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Connexin PF00029.19 GBG70894.1 - 0.012 15.4 3.8 0.016 15.0 3.8 1.2 1 0 0 1 1 1 0 Connexin Merozoite_SPAM PF07133.11 GBG70894.1 - 0.012 15.6 37.4 0.018 15.0 37.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CobT PF06213.12 GBG70894.1 - 0.017 14.6 23.9 0.023 14.1 23.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 GBG70894.1 - 0.022 13.7 22.8 0.03 13.3 22.8 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 GBG70894.1 - 0.039 13.8 15.1 0.052 13.4 15.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 GBG70894.1 - 0.044 12.6 11.7 0.063 12.1 11.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RPN2_C PF18004.1 GBG70894.1 - 0.18 11.7 17.7 0.28 11.1 17.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF5523 PF17661.1 GBG70894.1 - 0.22 11.2 19.9 0.32 10.7 19.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) TFB6 PF17110.5 GBG70894.1 - 0.23 11.2 10.9 0.38 10.5 10.9 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TERB2 PF15101.6 GBG70894.1 - 0.27 11.3 10.5 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 AAR2 PF05282.11 GBG70894.1 - 0.3 10.4 4.5 0.4 10.0 4.5 1.2 1 0 0 1 1 1 0 AAR2 protein Hid1 PF12722.7 GBG70894.1 - 0.42 8.7 8.9 0.51 8.4 8.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_pol_Rpc4 PF05132.14 GBG70894.1 - 0.45 10.9 7.7 0.72 10.3 7.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2722 PF10846.8 GBG70894.1 - 0.47 9.3 11.0 0.62 9.0 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 GBG70894.1 - 0.47 9.2 12.1 0.72 8.6 12.1 1.3 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG70894.1 - 0.65 8.7 10.1 0.79 8.4 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_polI_A34 PF08208.11 GBG70894.1 - 0.65 10.1 20.1 1.1 9.3 20.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Zip PF02535.22 GBG70894.1 - 1.9 7.6 13.3 2.6 7.2 13.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SMN PF06003.12 GBG70894.1 - 2.5 7.3 6.5 4.8 6.4 6.5 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF2457 PF10446.9 GBG70894.1 - 2.7 7.0 32.2 3.8 6.5 32.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.14 GBG70894.1 - 2.9 7.6 20.9 5.8 6.6 20.9 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spore_coat_CotO PF14153.6 GBG70894.1 - 2.9 7.8 18.4 5.1 7.0 18.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Smg8_Smg9 PF10220.9 GBG70894.1 - 3.4 5.8 12.5 4.4 5.5 12.5 1.1 1 0 0 1 1 1 0 Smg8_Smg9 ESM4 PF15952.5 GBG70894.1 - 4.2 7.8 10.4 9.2 6.7 10.4 1.6 1 0 0 1 1 1 0 Enhancer of split M4 family SLC12 PF03522.15 GBG70894.1 - 4.9 6.1 9.5 6.5 5.7 9.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2828 PF11443.8 GBG70894.1 - 5.6 4.9 10.1 7.4 4.5 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Vfa1 PF08432.10 GBG70894.1 - 5.7 7.2 24.5 7 6.9 23.6 1.4 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_11 PF13086.6 GBG70894.1 - 5.8 6.6 12.4 8.5 6.1 12.4 1.2 1 0 0 1 1 1 0 AAA domain DNA_pol_phi PF04931.13 GBG70894.1 - 6.2 4.8 36.4 8.4 4.4 36.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi MDM10 PF12519.8 GBG70894.1 - 7.8 5.2 6.4 11 4.8 6.4 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 VIR_N PF15912.5 GBG70894.1 - 9.1 5.8 15.8 14 5.2 15.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal ALMT PF11744.8 GBG70894.1 - 9.5 4.9 8.2 12 4.5 8.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Cyd_oper_YbgE PF09600.10 GBG70896.1 - 0.058 13.8 0.3 3.6 8.0 0.1 2.6 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) RT_RNaseH PF17917.1 GBG70897.1 - 2.3e-16 60.0 0.0 4.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70897.1 - 2e-13 50.2 0.0 4.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Topo_Zn_Ribbon PF08272.11 GBG70897.1 - 0.044 13.5 0.4 0.1 12.3 0.4 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG70897.1 - 0.46 10.6 2.3 0.91 9.7 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG70899.1 - 1e-05 25.4 4.2 1.6e-05 24.7 4.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG70899.1 - 0.034 14.0 2.5 0.054 13.3 2.5 1.3 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 GBG70899.1 - 4.1 7.8 8.1 9.3 6.7 0.8 2.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G PBP_sp32 PF07222.12 GBG70899.1 - 7.6 5.9 10.7 5.9 6.3 7.0 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Presenilin PF01080.17 GBG70899.1 - 9.1 4.9 4.8 11 4.7 4.8 1.3 1 0 0 1 1 1 0 Presenilin gag-asp_proteas PF13975.6 GBG70900.1 - 4.8e-05 23.8 0.0 9.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70900.1 - 0.0012 19.4 0.0 0.0022 18.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Phage-tail_1 PF09097.10 GBG70900.1 - 0.046 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 BUD22 PF09073.10 GBG70900.1 - 0.57 9.5 22.0 4.6 6.5 16.4 2.2 2 0 0 2 2 2 0 BUD22 Pap_E4 PF02711.14 GBG70900.1 - 7.8 7.5 11.0 8.9 7.4 6.8 2.7 2 0 0 2 2 2 0 E4 protein FGE-sulfatase PF03781.16 GBG70901.1 - 2.8e-16 59.9 0.2 0.00053 19.6 0.0 3.2 2 1 1 3 3 3 3 Sulfatase-modifying factor enzyme 1 TPR_2 PF07719.17 GBG70902.1 - 3.3e-07 29.9 2.2 0.00026 20.9 0.1 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG70902.1 - 0.0071 16.1 0.0 5.1 7.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG70902.1 - 0.0084 16.2 0.4 0.021 14.9 0.4 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2076 PF09849.9 GBG70902.1 - 0.022 14.8 0.5 0.039 14.0 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Selenoprotein_S PF06936.11 GBG70902.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF2613 PF11021.8 GBG70902.1 - 0.22 11.6 9.2 0.49 10.5 9.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) GerA PF03323.13 GBG70902.1 - 1.1 7.7 4.6 1.6 7.1 4.6 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein TPR_6 PF13174.6 GBG70902.1 - 2.5 8.9 5.5 44 5.0 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PPP4R2 PF09184.11 GBG70903.1 - 0.65 9.5 19.3 0.42 10.1 17.4 1.7 2 0 0 2 2 2 0 PPP4R2 Cwf_Cwc_15 PF04889.12 GBG70903.1 - 1.1 8.9 21.7 1.2 8.8 19.6 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RT_RNaseH_2 PF17919.1 GBG70904.1 - 2.7e-27 94.7 0.0 8e-27 93.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70904.1 - 1.8e-24 86.5 0.0 3.4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70904.1 - 1.8e-23 82.8 0.0 6.2e-23 81.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG70904.1 - 0.0046 17.2 0.9 0.03 14.6 0.0 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG70904.1 - 0.023 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease NOA36 PF06524.12 GBG70905.1 - 0.15 11.4 4.6 0.34 10.2 4.6 1.5 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG70905.1 - 0.82 7.7 11.8 1.4 6.9 11.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 GBG70905.1 - 1.4 8.6 5.6 3.3 7.5 5.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.12 GBG70905.1 - 1.9 7.8 12.3 0.36 10.2 3.4 2.3 2 0 0 2 2 2 0 SDA1 BHD_2 PF10404.9 GBG70905.1 - 2.7 9.0 5.6 3.8 8.5 3.2 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 Cnd2 PF05786.14 GBG70905.1 - 3.1 6.4 7.6 6 5.4 7.6 1.4 1 0 0 1 1 1 0 Condensin complex subunit 2 Glyco_hydro_17 PF00332.18 GBG70906.1 - 2.9e-53 181.5 0.0 4e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 zf-CCHC PF00098.23 GBG70906.1 - 1.5e-05 24.8 3.5 2.8e-05 24.0 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG70906.1 - 0.11 12.2 0.5 0.21 11.3 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG70906.1 - 0.28 11.2 1.3 0.61 10.1 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG70908.1 - 8e-19 68.0 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Glyco_hydro_17 PF00332.18 GBG70909.1 - 9.6e-34 117.4 0.1 1.2e-33 117.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.13 GBG70909.1 - 3.1e-12 47.0 0.2 4.8e-12 46.4 0.2 1.3 1 0 0 1 1 1 1 X8 domain Glyco_hydro_17 PF00332.18 GBG70911.1 - 7.2e-54 183.5 0.0 1e-53 183.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 RT_RNaseH_2 PF17919.1 GBG70911.1 - 1.1e-24 86.4 0.0 2.9e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70911.1 - 2.5e-23 82.4 0.1 9.6e-23 80.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70911.1 - 6.4e-23 81.4 0.0 1.4e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) X8 PF07983.13 GBG70911.1 - 1e-14 55.0 0.4 2.3e-14 53.8 0.4 1.7 1 0 0 1 1 1 1 X8 domain rve PF00665.26 GBG70911.1 - 2.3e-09 37.5 0.1 9.3e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG70911.1 - 1.9e-05 24.7 1.8 3.8e-05 23.7 1.8 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG70911.1 - 0.007 16.9 0.0 0.023 15.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG70911.1 - 0.013 15.8 0.5 0.058 13.7 0.1 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG70911.1 - 0.023 15.3 0.0 0.059 14.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF4187 PF13821.6 GBG70911.1 - 0.051 13.4 0.9 0.16 11.8 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RT_RNaseH PF17917.1 GBG70912.1 - 1.1e-20 73.9 0.0 2.3e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70912.1 - 1.4e-19 70.0 0.0 2.6e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70912.1 - 4.5e-05 23.1 0.0 8.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Jnk-SapK_ap_N PF09744.9 GBG70912.1 - 0.0014 18.9 3.4 0.0014 18.9 3.4 2.3 2 1 0 2 2 2 1 JNK_SAPK-associated protein-1 DUF3347 PF11827.8 GBG70912.1 - 0.085 13.0 0.5 0.23 11.6 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Glyco_hydro_17 PF00332.18 GBG70914.1 - 4.8e-55 187.3 0.0 5.9e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.13 GBG70914.1 - 1.1e-14 54.9 0.2 1.8e-14 54.1 0.2 1.4 1 0 0 1 1 1 1 X8 domain EF-hand_1 PF00036.32 GBG70915.1 - 3.3e-17 60.7 4.8 9.3e-08 31.1 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 GBG70915.1 - 2.4e-16 59.9 8.2 4.8e-11 42.9 1.4 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG70915.1 - 4.8e-15 54.1 8.3 3.4e-06 26.5 0.3 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 GBG70915.1 - 4.2e-09 35.5 5.4 0.0016 17.9 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GBG70915.1 - 4.5e-09 36.0 6.1 1.4e-05 24.9 0.5 3.0 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GBG70915.1 - 0.0066 16.8 0.4 0.0099 16.2 0.4 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region LIAS_N PF16881.5 GBG70915.1 - 0.091 13.2 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family EF-hand_10 PF14788.6 GBG70915.1 - 0.11 12.3 0.5 5.8 6.9 0.0 2.5 2 1 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 GBG70915.1 - 0.23 11.5 5.8 3 7.9 0.1 2.7 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Glyco_hydro_17 PF00332.18 GBG70917.1 - 8e-57 193.2 0.0 1.1e-56 192.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 RT_RNaseH_2 PF17919.1 GBG70917.1 - 6.8e-28 96.6 0.0 1.4e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70917.1 - 2.9e-25 88.6 0.0 6.4e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase X8 PF07983.13 GBG70917.1 - 5.4e-12 46.2 3.1 9.6e-12 45.4 3.1 1.4 1 0 0 1 1 1 1 X8 domain SOG2 PF10428.9 GBG70917.1 - 4.3 6.4 13.0 8 5.5 13.0 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein UEV PF05743.13 GBG70919.1 - 5.3e-31 107.0 0.1 9.3e-31 106.2 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 GBG70919.1 - 2.8e-22 78.4 0.1 5.9e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 GBG70919.1 - 1.3e-05 24.9 0.1 2.5e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GBG70919.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 RWD domain MRP-S34 PF16053.5 GBG70920.1 - 1.6e-10 40.8 0.2 3.1e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 zf-B_box PF00643.24 GBG70921.1 - 2.1e-10 40.6 9.8 3.7e-06 27.0 3.4 2.8 3 0 0 3 3 3 2 B-box zinc finger CEBP_ZZ PF16366.5 GBG70921.1 - 0.00021 21.5 10.4 0.016 15.4 3.8 2.8 2 0 0 2 2 2 2 Cytoplasmic polyadenylation element-binding protein ZZ domain C1_2 PF03107.16 GBG70921.1 - 0.95 9.8 9.4 4.9 7.6 0.8 2.7 2 0 0 2 2 2 0 C1 domain DUF2318 PF10080.9 GBG70921.1 - 7.4 6.7 9.9 11 6.2 3.5 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) LON_substr_bdg PF02190.16 GBG70922.1 - 3.1e-26 92.5 0.0 3.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Tautomerase PF01361.21 GBG70923.1 - 1.1 9.2 5.5 1.2 9.1 2.0 2.7 2 1 0 2 2 2 0 Tautomerase enzyme RRM_1 PF00076.22 GBG70925.1 - 2e-07 30.7 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GBG70926.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PQ-loop PF04193.14 GBG70927.1 - 9.9e-28 95.7 12.8 2.2e-14 53.0 0.5 2.6 3 0 0 3 3 3 2 PQ loop repeat EII-Sor PF03609.14 GBG70927.1 - 0.00023 20.7 1.9 0.0015 18.0 1.2 2.1 2 0 0 2 2 2 1 PTS system sorbose-specific iic component MtN3_slv PF03083.16 GBG70927.1 - 0.00041 20.3 1.1 0.00041 20.3 1.1 2.5 2 1 0 2 2 2 1 Sugar efflux transporter for intercellular exchange DUF5090 PF17009.5 GBG70927.1 - 9 6.2 11.2 0.26 11.2 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Solute_trans_a PF03619.16 GBG70928.1 - 2.2e-37 129.0 1.7 3.3e-37 128.5 1.7 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TCR PF03638.15 GBG70928.1 - 9.2e-13 48.3 25.8 1.7e-12 47.4 25.8 1.5 1 0 0 1 1 1 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain Baculo_PEP_C PF04513.12 GBG70928.1 - 0.12 12.4 0.9 0.26 11.3 0.9 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Trans_reg_C PF00486.28 GBG70928.1 - 0.15 12.1 0.4 0.46 10.6 0.4 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal DUF4559 PF15112.6 GBG70928.1 - 2.5 7.7 5.5 5 6.7 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) UPF0242 PF06785.11 GBG70928.1 - 4.7 7.3 9.7 11 6.0 9.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mpp10 PF04006.12 GBG70929.1 - 4.5 5.6 38.2 5.1 5.4 38.2 1.1 1 0 0 1 1 1 0 Mpp10 protein CCSAP PF15748.5 GBG70929.1 - 5 7.2 16.6 6.2 6.9 16.6 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM60A PF15396.6 GBG70929.1 - 6.3 6.7 8.3 8.1 6.4 8.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.14 GBG70929.1 - 6.7 4.9 34.4 7.9 4.6 34.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 GBG70929.1 - 7.1 5.5 9.6 7.1 5.5 9.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF659 PF04937.15 GBG70930.1 - 2e-36 125.2 0.0 4.2e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SOG2 PF10428.9 GBG70930.1 - 2.1 7.5 27.4 3.4 6.8 27.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RT_RNaseH_2 PF17919.1 GBG70931.1 - 5.6e-23 80.9 0.0 9.5e-23 80.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70931.1 - 5.4e-20 71.2 0.4 1.1e-19 70.2 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG70931.1 - 2.5e-14 53.4 0.0 5.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70931.1 - 4.8e-10 39.3 0.0 9e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG70931.1 - 5e-08 33.2 0.0 1.5e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG70931.1 - 0.0072 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG70932.1 - 7.8e-25 86.8 0.0 1.6e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70932.1 - 8.6e-23 80.6 0.0 1.9e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG70932.1 - 1.7e-13 50.8 0.0 4.1e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG70932.1 - 2.4e-11 43.5 0.0 8.2e-11 41.8 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG70932.1 - 0.073 13.6 0.1 0.17 12.5 0.1 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_Tnp_4 PF13359.6 GBG70934.1 - 6.5e-31 107.1 0.0 2.3e-30 105.4 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG70934.1 - 4e-13 49.5 0.0 6.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG70934.1 - 0.016 14.9 0.2 2.1 7.9 0.4 2.6 3 0 0 3 3 3 0 Transposase DDE domain RVT_1 PF00078.27 GBG70935.1 - 7.9e-33 113.8 0.0 1.3e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MIP PF00230.20 GBG70937.1 - 4.3e-69 232.7 17.4 5e-69 232.5 17.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein DinB PF05163.12 GBG70938.1 - 0.025 14.5 0.7 0.038 13.9 0.7 1.3 1 0 0 1 1 1 0 DinB family Nop14 PF04147.12 GBG70938.1 - 0.27 9.4 13.7 0.29 9.3 13.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG70938.1 - 0.62 8.3 13.1 0.77 8.0 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG70938.1 - 1.1 8.6 17.0 1.3 8.4 17.0 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG70938.1 - 6.4 6.0 18.3 7.6 5.8 18.3 1.1 1 0 0 1 1 1 0 BUD22 Arm PF00514.23 GBG70939.1 - 2e-05 24.4 11.0 0.2 11.8 0.4 5.5 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat RasGEF_N PF00618.20 GBG70939.1 - 0.13 12.6 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 RasGEF N-terminal motif U-box PF04564.15 GBG70940.1 - 2.2e-14 53.4 0.0 4.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GBG70940.1 - 0.0004 20.1 0.0 0.00086 19.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RPW8 PF05659.11 GBG70940.1 - 0.0016 18.1 2.0 0.0044 16.7 0.2 2.3 1 1 1 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1843 PF08898.10 GBG70940.1 - 0.1 13.1 2.5 0.12 12.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DBINO PF13892.6 GBG70941.1 - 1.7 9.0 14.2 3.1 8.2 14.2 1.3 1 0 0 1 1 1 0 DNA-binding domain RR_TM4-6 PF06459.12 GBG70941.1 - 2 8.2 10.3 3.3 7.5 10.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp_protease PF09668.10 GBG70942.1 - 0.011 15.6 0.9 0.014 15.2 0.1 1.6 2 0 0 2 2 2 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG70942.1 - 0.029 15.0 0.1 0.083 13.5 0.1 1.8 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG70942.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG70945.1 - 2.7e-27 94.7 0.0 5.2e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70945.1 - 9.2e-24 84.2 0.1 1.4e-23 83.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG70945.1 - 1.4e-22 79.9 0.0 3e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3439 PF11921.8 GBG70948.1 - 0.0072 16.3 0.2 0.0072 16.3 0.2 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF3439) SNN_linker PF09050.10 GBG70948.1 - 0.13 12.1 3.4 4.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Stannin unstructured linker Macoilin PF09726.9 GBG70948.1 - 6.9 5.1 16.5 8.6 4.8 16.5 1.1 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 GBG70948.1 - 7.5 4.6 23.0 12 4.0 23.0 1.2 1 0 0 1 1 1 0 Nop14-like family DUF659 PF04937.15 GBG70951.1 - 3e-30 105.1 0.0 5.5e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG70951.1 - 9.5e-10 38.1 0.1 2e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PIF1 PF05970.14 GBG70952.1 - 2.6e-94 316.4 0.0 4.2e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 GBG70952.1 - 1.4e-39 136.3 0.0 2.9e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus rRNA_proc-arch PF13234.6 GBG70952.1 - 4.5e-33 115.3 0.0 1.5e-32 113.6 0.0 1.9 1 1 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 GBG70952.1 - 2.7e-26 92.2 0.0 2.7e-26 92.2 0.0 2.0 2 0 0 2 2 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 GBG70952.1 - 2e-15 56.8 0.3 2e-15 56.8 0.3 2.4 2 1 0 2 2 1 1 Ski2 N-terminal region DEAD PF00270.29 GBG70952.1 - 3.1e-14 53.1 0.0 4.8e-13 49.3 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GBG70952.1 - 2.7e-08 33.8 0.0 1.1e-07 31.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain SDA1 PF05285.12 GBG70952.1 - 5.1e-06 26.1 43.4 5.1e-06 26.1 43.4 3.8 4 0 0 4 4 2 1 SDA1 Helicase_C PF00271.31 GBG70952.1 - 0.0015 18.8 0.0 0.0044 17.4 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GBG70952.1 - 0.0017 18.6 0.0 0.95 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GBG70952.1 - 0.0018 18.6 0.0 0.015 15.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GBG70952.1 - 0.0048 17.3 0.0 0.8 10.1 0.0 3.5 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 GBG70952.1 - 0.16 11.0 0.0 8.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 GBG70952.1 - 0.37 10.8 0.0 0.37 10.8 0.0 3.3 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit Retrotrans_gag PF03732.17 GBG70953.1 - 0.0091 16.3 0.1 0.074 13.3 0.0 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG70953.1 - 0.017 15.2 11.3 0.018 15.1 1.0 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG70953.1 - 1.7 8.7 6.8 4.3 7.4 0.6 2.7 2 0 0 2 2 2 0 Zinc knuckle Smg8_Smg9 PF10220.9 GBG70954.1 - 2.4e-58 198.2 4.5 1.3e-38 133.0 0.0 6.3 6 0 0 6 6 6 6 Smg8_Smg9 MAGI_u1 PF16663.5 GBG70954.1 - 0.13 12.3 0.0 0.48 10.5 0.0 1.9 1 0 0 1 1 1 0 Unstructured region on MAGI RT_RNaseH_2 PF17919.1 GBG70955.1 - 9.8e-30 102.6 0.0 1.2e-14 54.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70955.1 - 4.5e-19 68.7 0.0 1.1e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG70955.1 - 1.6e-16 60.5 0.0 2.4e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG70955.1 - 3.5e-09 36.9 0.4 1.8e-08 34.6 0.1 2.3 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG70955.1 - 9.7e-09 35.0 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 GBG70956.1 - 1.5e-23 83.5 0.0 6.7e-20 71.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG70956.1 - 3.4e-07 29.8 0.0 0.0022 17.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GBG70956.1 - 0.00021 21.3 0.1 0.00021 21.3 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GBG70956.1 - 0.0003 20.2 0.0 0.00093 18.6 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GBG70956.1 - 0.00056 18.8 0.1 0.00056 18.8 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 GBG70956.1 - 0.012 15.3 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GBG70956.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family HemY_N PF07219.13 GBG70957.1 - 0.13 12.5 3.7 0.15 12.3 3.7 1.2 1 0 0 1 1 1 0 HemY protein N-terminus DUF572 PF04502.13 GBG70959.1 - 0.097 12.3 18.1 0.11 12.0 18.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CRT10 PF08728.10 GBG70959.1 - 9.8 4.2 12.2 12 3.9 12.2 1.0 1 0 0 1 1 1 0 CRT10 zf-CCHC PF00098.23 GBG70960.1 - 0.00014 21.7 1.8 0.0003 20.7 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle CDC27 PF09507.10 GBG70960.1 - 0.022 14.1 20.7 0.033 13.6 20.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Rgp1 PF08737.10 GBG70960.1 - 0.077 12.2 7.9 0.12 11.5 7.9 1.3 1 0 0 1 1 1 0 Rgp1 DUF572 PF04502.13 GBG70960.1 - 0.11 12.0 20.9 0.15 11.7 20.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) InPase PF18823.1 GBG70961.1 - 2.9 7.6 5.3 8.9 6.0 5.3 1.7 1 1 0 1 1 1 0 Inorganic Pyrophosphatase Nop14 PF04147.12 GBG70962.1 - 1.1 7.4 6.0 1.3 7.1 6.0 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG70963.1 - 0.0022 17.5 14.1 0.004 16.7 14.1 1.4 1 0 0 1 1 1 1 SDA1 SpoIIP PF07454.11 GBG70963.1 - 0.018 14.5 3.1 0.026 14.0 3.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 GBG70963.1 - 0.22 11.6 1.6 0.42 10.7 1.6 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Presenilin PF01080.17 GBG70963.1 - 0.3 9.8 4.2 0.52 9.0 4.2 1.3 1 0 0 1 1 1 0 Presenilin DARPP-32 PF05395.12 GBG70963.1 - 0.55 10.5 14.0 1.1 9.4 14.0 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 NPR3 PF03666.13 GBG70963.1 - 1.4 7.6 5.2 2.1 7.1 5.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ORC6 PF05460.13 GBG70963.1 - 2.5 7.3 0.0 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Mpp10 PF04006.12 GBG70963.1 - 7.4 4.9 26.2 11 4.3 26.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Cpn60_TCP1 PF00118.24 GBG70964.1 - 2.9e-171 570.4 4.3 3.3e-171 570.2 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family pXO2-72 PF17443.2 GBG70964.1 - 0.13 12.5 0.0 10 6.5 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein pXO2-72 Pam16 PF03656.13 GBG70966.1 - 3e-05 24.0 0.0 3.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 GBG70966.1 - 0.00011 22.3 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Apolipoprotein PF01442.18 GBG70968.1 - 1e-08 35.3 49.0 7.1e-08 32.6 39.6 2.8 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GBG70968.1 - 1.3e-06 28.9 47.8 0.032 14.8 7.5 5.1 1 1 4 5 5 5 5 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GBG70968.1 - 3.8e-06 27.3 53.0 0.38 11.3 4.3 5.5 1 1 3 4 4 4 3 YtxH-like protein LEA_4 PF02987.16 GBG70968.1 - 0.00028 20.9 67.9 0.00075 19.5 7.9 7.2 2 2 5 7 7 7 3 Late embryogenesis abundant protein ApoLp-III PF07464.11 GBG70968.1 - 0.021 14.9 37.5 0.032 14.3 15.6 3.5 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF630 PF04783.12 GBG70968.1 - 0.22 11.7 0.1 0.22 11.7 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF630) LacI PF00356.21 GBG70968.1 - 0.57 10.0 0.1 0.57 10.0 0.1 4.5 6 0 0 6 6 6 0 Bacterial regulatory proteins, lacI family ATP-synt_B PF00430.18 GBG70968.1 - 0.81 9.8 62.5 0.29 11.2 16.1 4.1 1 1 3 4 4 4 0 ATP synthase B/B' CF(0) Exonuc_VII_L PF02601.15 GBG70968.1 - 1.1 8.8 25.0 1.3 8.5 12.4 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit CmlA_N PF18456.1 GBG70968.1 - 1.5 8.1 8.2 7.8 5.7 0.5 2.5 1 1 1 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain Tai4 PF16695.5 GBG70968.1 - 2.5 8.7 7.9 0.68 10.5 0.2 3.2 1 1 3 4 4 4 0 Type VI secretion system (T6SS), amidase immunity protein DUF4533 PF15047.6 GBG70968.1 - 4.6 6.7 19.8 2.5 7.6 4.4 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4533) hDGE_amylase PF14701.6 GBG70968.1 - 8.9 5.3 18.7 2.9 6.9 11.2 2.0 1 1 1 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain PITH PF06201.13 GBG70969.1 - 1.2e-29 103.5 1.2 1.3e-18 67.7 0.1 2.1 1 1 1 2 2 2 2 PITH domain DUF2541 PF10807.8 GBG70969.1 - 0.0052 16.9 0.1 0.042 13.9 0.1 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF2541) zf-CCHC PF00098.23 GBG70970.1 - 4e-05 23.5 2.2 4e-05 23.5 2.2 1.9 2 0 0 2 2 2 1 Zinc knuckle LRR_8 PF13855.6 GBG70971.1 - 5.1e-12 45.4 18.2 0.0074 16.0 1.1 7.3 5 2 3 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 GBG70971.1 - 5.8e-09 36.1 24.7 0.0057 17.1 0.7 7.7 5 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG70971.1 - 1.3e-06 28.0 2.4 15 6.0 0.0 7.7 10 0 0 10 10 10 1 Leucine Rich repeat LRR_1 PF00560.33 GBG70971.1 - 0.00082 19.6 25.4 1.3 9.8 0.0 9.3 10 2 0 10 10 10 2 Leucine Rich Repeat PPC PF04151.15 GBG70971.1 - 0.042 14.9 0.4 0.13 13.4 0.4 1.9 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain DUF1180 PF06679.12 GBG70971.1 - 0.26 11.7 1.7 0.67 10.3 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) LapA_dom PF06305.11 GBG70971.1 - 2.2 8.2 4.0 20 5.1 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RVT_1 PF00078.27 GBG70973.1 - 8.1e-17 61.5 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lin-8 PF03353.15 GBG70973.1 - 1.4 8.4 10.2 2.3 7.7 10.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 GBG70973.1 - 2.3 7.6 23.1 3.8 6.8 23.1 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG70973.1 - 2.7 6.1 22.9 4.5 5.4 22.9 1.3 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 GBG70973.1 - 3 8.1 16.8 5.7 7.2 16.8 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.14 GBG70973.1 - 6.9 4.8 14.8 10 4.2 14.8 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC PF00098.23 GBG70974.1 - 1.1e-05 25.3 3.0 2.1e-05 24.4 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG70974.1 - 0.00051 19.8 2.8 0.001 18.8 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4192 PF13830.6 GBG70974.1 - 0.076 13.1 2.8 0.093 12.8 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) GrpE PF01025.19 GBG70974.1 - 0.15 11.7 11.2 0.21 11.2 11.2 1.1 1 0 0 1 1 1 0 GrpE KIND PF16474.5 GBG70974.1 - 0.32 10.9 7.2 0.57 10.1 7.2 1.4 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Borrelia_P83 PF05262.11 GBG70974.1 - 3.7 5.9 13.1 4.6 5.6 13.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S49_N PF08496.10 GBG70974.1 - 4 7.5 9.0 6.6 6.8 9.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Conotoxin PF02950.17 GBG70974.1 - 9.2 7.4 8.2 36 5.5 3.1 2.8 2 0 0 2 2 2 0 Conotoxin G10 PF01125.17 GBG70975.1 - 1.5e-65 219.4 8.9 1.7e-65 219.3 8.9 1.0 1 0 0 1 1 1 1 G10 protein Peptidase_M16 PF00675.20 GBG70976.1 - 0.19 11.7 3.7 0.36 10.8 3.7 1.4 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) NARP1 PF12569.8 GBG70976.1 - 0.51 9.2 10.8 0.7 8.7 10.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S64 PF08192.11 GBG70976.1 - 2 6.8 4.3 2.4 6.5 4.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Sec62 PF03839.16 GBG70976.1 - 2.3 7.7 6.8 3.2 7.2 6.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 GBG70976.1 - 3.4 7.3 5.4 5.6 6.7 5.4 1.3 1 0 0 1 1 1 0 Connexin gag-asp_proteas PF13975.6 GBG70977.1 - 0.00032 21.2 1.2 0.0011 19.5 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG70977.1 - 0.00077 20.1 0.4 0.003 18.2 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease BNIP3 PF06553.12 GBG70977.1 - 6.8 6.3 6.0 12 5.5 6.0 1.3 1 0 0 1 1 1 0 BNIP3 Ribosomal_S25 PF03297.15 GBG70978.1 - 7.2e-43 144.9 3.9 8.7e-43 144.6 3.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 GBG70978.1 - 0.0038 16.8 0.1 0.0052 16.3 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 GBG70978.1 - 0.0041 17.0 0.1 0.0058 16.5 0.1 1.2 1 0 0 1 1 1 1 MarR family RPA_C PF08784.11 GBG70978.1 - 0.016 15.9 0.0 0.021 15.5 0.0 1.1 1 0 0 1 1 1 0 Replication protein A C terminal HTH_CodY PF08222.11 GBG70978.1 - 0.018 14.5 0.5 0.033 13.7 0.4 1.4 1 1 0 1 1 1 0 CodY helix-turn-helix domain AIPR PF10592.9 GBG70978.1 - 0.02 14.5 0.1 0.021 14.5 0.1 1.1 1 0 0 1 1 1 0 AIPR protein DUF3516 PF12029.8 GBG70978.1 - 0.048 12.7 0.3 0.048 12.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) zf-RING_UBOX PF13445.6 GBG70979.1 - 6.4e-09 35.7 6.4 1.5e-08 34.5 6.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG70979.1 - 6.7e-08 32.4 5.0 1.4e-07 31.3 5.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GBG70979.1 - 2.2e-07 31.1 6.4 6.6e-07 29.6 6.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GBG70979.1 - 2.2e-06 27.4 4.3 7e-06 25.8 4.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG70979.1 - 3.8e-06 26.7 5.8 8.4e-06 25.6 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG70979.1 - 0.00051 20.2 7.8 0.0019 18.3 7.8 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GBG70979.1 - 0.0011 18.8 9.4 0.0058 16.4 9.4 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG70979.1 - 0.0012 18.6 10.7 0.002 17.9 7.3 2.7 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 GBG70979.1 - 0.013 15.4 1.2 0.025 14.5 1.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 GBG70979.1 - 0.015 15.0 4.4 0.015 15.0 4.4 2.4 3 1 0 3 3 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 GBG70979.1 - 0.063 13.4 5.3 0.29 11.3 5.1 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 GBG70979.1 - 0.069 12.9 0.2 0.069 12.9 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-UDP PF14569.6 GBG70979.1 - 0.17 12.0 1.4 2.4 8.4 0.2 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger DZR PF12773.7 GBG70979.1 - 0.32 11.0 5.2 0.87 9.7 2.5 2.6 2 1 1 3 3 2 0 Double zinc ribbon DUF1272 PF06906.11 GBG70979.1 - 0.51 10.5 4.3 1.2 9.3 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DNA_ligase_ZBD PF03119.16 GBG70979.1 - 0.73 9.9 6.4 12 6.0 0.0 3.3 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 GBG70979.1 - 0.81 9.9 4.8 21 5.3 0.1 2.8 2 1 0 2 2 2 0 Zinc ribbon domain zf-RRN7 PF11781.8 GBG70979.1 - 4.6 7.0 7.9 11 5.8 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 YacG PF03884.14 GBG70979.1 - 5.2 6.9 6.7 2.4 8.0 0.1 2.4 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Zn_Tnp_IS1595 PF12760.7 GBG70979.1 - 5.6 7.0 7.5 12 6.0 0.1 3.0 3 0 0 3 3 3 0 Transposase zinc-ribbon domain SCIMP PF15050.6 GBG70979.1 - 7.1 7.1 7.1 13 6.2 7.1 1.4 1 0 0 1 1 1 0 SCIMP protein Prim_Zn_Ribbon PF08273.12 GBG70979.1 - 7.5 6.9 8.5 7.4 7.0 4.9 2.6 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DNA_RNApol_7kD PF03604.13 GBG70979.1 - 9 6.1 10.1 9.3 6.0 3.1 3.9 4 1 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S21e PF01249.18 GBG70981.1 - 2.4e-38 130.1 0.0 2.8e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e CENP-F_leu_zip PF10473.9 GBG70983.1 - 8.5e-05 22.6 15.8 8.5e-05 22.6 15.8 2.9 4 0 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RNase_J_C PF17770.1 GBG70983.1 - 0.15 13.1 0.2 0.15 13.1 0.2 2.7 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain Cir_N PF10197.9 GBG70983.1 - 1.9 8.7 0.0 1.9 8.7 0.0 6.0 5 2 1 6 6 6 0 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_5 PF14787.6 GBG70984.1 - 0.44 10.3 3.6 1.2 9.0 3.6 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG70984.1 - 0.82 9.9 4.6 2 8.7 4.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG70985.1 - 0.027 14.8 0.0 0.12 12.7 0.0 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein zf-FCS PF06467.14 GBG70985.1 - 0.06 13.3 0.4 0.21 11.6 0.4 1.9 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CCHC PF00098.23 GBG70985.1 - 0.58 10.3 3.4 2 8.7 3.4 1.9 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG70986.1 - 3e-20 72.5 0.0 6.5e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG70986.1 - 2.1e-18 66.2 0.0 5.3e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG70986.1 - 0.02 15.4 0.0 0.053 14.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CCDC106 PF15794.5 GBG70986.1 - 2.1 8.0 7.9 0.33 10.7 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Sec7 PF01369.20 GBG70987.1 - 4.2e-69 231.9 0.0 1.1e-68 230.5 0.0 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GBG70987.1 - 1.8e-45 154.7 1.0 1.8e-45 154.7 1.0 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 GBG70987.1 - 3.1e-38 131.2 2.5 3.1e-35 121.4 0.8 3.3 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 GBG70987.1 - 3.5e-32 110.1 8.9 2.4e-31 107.4 0.8 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Mon2_C PF16206.5 GBG70987.1 - 2e-11 42.8 0.0 1e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 C-terminal region of Mon2 protein Jiv90 PF14901.6 GBG70988.1 - 1.1e-29 102.4 6.9 2.4e-29 101.3 6.9 1.6 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone DnaJ PF00226.31 GBG70988.1 - 3.5e-17 62.3 0.1 1.6e-16 60.1 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain DUF4677 PF15726.5 GBG70988.1 - 1.1 9.4 5.4 11 6.1 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) ICL PF00463.21 GBG70991.1 - 3.6e-256 850.7 0.5 4.1e-256 850.5 0.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GBG70991.1 - 1.8e-12 47.2 0.0 4e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase RVT_1 PF00078.27 GBG70992.1 - 7.3e-29 100.9 0.0 1.1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG70992.1 - 0.0018 18.9 0.0 0.0063 17.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease DUF222 PF02720.17 GBG70993.1 - 0.032 13.7 0.0 0.056 12.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF222) PH PF00169.29 GBG70994.1 - 1.2e-09 38.6 0.0 2.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GBG70994.1 - 1.7e-05 25.0 0.0 3.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GBG70994.1 - 0.037 14.4 0.8 1.1 9.8 0.8 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain FPP PF05911.11 GBG70994.1 - 0.72 8.0 4.8 0.43 8.7 1.0 1.9 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil RVT_1 PF00078.27 GBG70995.1 - 7.9e-28 97.5 0.0 1.7e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70995.1 - 1.1e-26 92.8 0.0 3.2e-26 91.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70995.1 - 4.2e-23 81.6 0.0 1.3e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG70995.1 - 4.9e-06 27.1 0.0 1.1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70995.1 - 5.5e-05 23.7 0.0 0.00013 22.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG70995.1 - 9.2e-05 22.5 0.0 0.00024 21.1 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG70995.1 - 0.00028 20.7 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG70995.1 - 0.0018 18.0 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RNR_Alpha PF17975.1 GBG70995.1 - 0.11 13.1 0.0 0.43 11.1 0.0 2.0 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain Oxysterol_BP PF01237.18 GBG70996.1 - 6.2e-107 357.7 0.0 8e-107 357.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Mg_chelatase_C PF13335.6 GBG70997.1 - 0.00014 22.4 0.3 0.4 11.4 0.1 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI C-terminal Retrotrans_gag PF03732.17 GBG70997.1 - 0.21 11.9 1.2 0.4 11.0 0.1 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG70999.1 - 5.7e-27 94.7 0.0 1.1e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG70999.1 - 3.1e-26 91.3 0.0 9.2e-26 89.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG70999.1 - 1e-22 80.4 0.0 2.8e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG70999.1 - 2.1e-16 59.8 0.4 5e-16 58.6 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG70999.1 - 1.3e-09 38.2 0.0 3.8e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG70999.1 - 3.6e-06 27.5 0.0 7.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG70999.1 - 2.7e-05 24.6 0.0 6.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG70999.1 - 0.00024 20.9 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG70999.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG70999.1 - 0.0021 18.3 0.1 0.026 14.8 0.0 2.8 2 1 1 3 3 3 1 Retrotransposon gag protein TMF_TATA_bd PF12325.8 GBG71000.1 - 0.015 15.5 0.5 0.015 15.5 0.5 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 GBG71000.1 - 0.018 15.4 1.0 0.018 15.4 1.0 3.6 3 2 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RNR_Alpha PF17975.1 GBG71000.1 - 0.38 11.3 0.1 0.38 11.3 0.1 2.2 2 1 0 2 2 2 0 Ribonucleotide reductase alpha domain PIEZO PF15917.5 GBG71000.1 - 0.66 9.4 9.6 0.31 10.5 7.5 1.4 1 1 1 2 2 2 0 Piezo DUF4288 PF14119.6 GBG71000.1 - 2.5 8.6 5.4 3.5 8.1 4.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) DUF4407 PF14362.6 GBG71000.1 - 3.7 6.8 20.8 2.9 7.2 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 GBG71000.1 - 4.2 7.4 8.7 3.4 7.7 0.1 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus STAG PF08514.11 GBG71000.1 - 5.4 7.0 9.2 1 9.3 0.4 2.5 2 0 0 2 2 2 0 STAG domain RT_RNaseH_2 PF17919.1 GBG71002.1 - 3e-34 117.1 0.0 5.8e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71002.1 - 1.1e-31 109.2 0.0 1.9e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71002.1 - 7.8e-19 68.1 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG71002.1 - 1.2e-08 34.6 1.2 2.2e-08 33.8 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG71002.1 - 0.01 15.6 2.7 0.023 14.5 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4419 PF14388.6 GBG71004.1 - 2.4e-60 204.5 0.0 1.3e-42 146.3 0.0 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF4419) SDA1 PF05285.12 GBG71004.1 - 8.5e-06 25.4 2.3 8.5e-06 25.4 2.3 3.2 3 0 0 3 3 3 2 SDA1 DUF1676 PF07898.13 GBG71004.1 - 1.5e-05 25.1 3.2 0.091 12.8 0.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1676) Connexin PF00029.19 GBG71004.1 - 0.0005 19.9 2.2 3 7.5 4.7 2.4 2 0 0 2 2 2 2 Connexin DUF898 PF05987.13 GBG71004.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) CSG2 PF16965.5 GBG71004.1 - 0.21 10.5 2.9 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Ceramide synthase regulator MCM_bind PF09739.9 GBG71004.1 - 0.26 9.7 2.5 0.58 8.5 2.5 1.5 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Ac76 PF05814.11 GBG71004.1 - 0.95 9.5 9.2 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) Zip PF02535.22 GBG71004.1 - 1.6 7.9 5.6 3.6 6.7 0.4 2.8 2 1 0 2 2 2 0 ZIP Zinc transporter DUF2615 PF11027.8 GBG71004.1 - 1.8 8.8 7.6 0.3 11.2 0.5 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Orf78 PF06024.12 GBG71004.1 - 4.3 7.7 20.6 0.29 11.5 0.2 4.0 3 1 1 4 4 4 0 Orf78 (ac78) DUF983 PF06170.12 GBG71004.1 - 9.1 6.8 7.5 13 6.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF983) RVT_1 PF00078.27 GBG71005.1 - 3e-23 82.5 0.1 5e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71005.1 - 8.5e-09 35.4 0.0 2.7e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG71005.1 - 7.3e-07 29.0 0.0 2.6e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71005.1 - 9e-05 23.0 0.1 0.00038 20.9 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71005.1 - 0.00038 21.0 0.0 0.00086 19.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71005.1 - 0.0021 17.8 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG71005.1 - 0.032 14.5 0.0 0.098 13.0 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase TolA_bind_tri PF16331.5 GBG71005.1 - 0.31 11.2 12.4 0.019 15.1 3.7 3.3 2 1 0 2 2 2 0 TolA binding protein trimerisation LAT PF15234.6 GBG71005.1 - 3.6 7.2 11.0 8 6.1 11.0 1.6 1 0 0 1 1 1 0 Linker for activation of T-cells RVT_1 PF00078.27 GBG71006.1 - 1.5e-23 83.4 0.1 2.5e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71006.1 - 3.9e-09 36.4 0.1 1.6e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG71006.1 - 2.8e-07 30.4 0.0 1.4e-06 28.1 0.0 2.2 2 2 1 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71006.1 - 4.6e-05 23.9 0.1 0.00021 21.8 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71006.1 - 0.00021 21.8 0.0 0.00048 20.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71006.1 - 0.0012 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease TolA_bind_tri PF16331.5 GBG71006.1 - 0.012 15.7 3.8 0.012 15.7 3.8 2.6 1 1 0 1 1 1 0 TolA binding protein trimerisation RT_RNaseH PF17917.1 GBG71006.1 - 0.016 15.5 0.1 0.059 13.7 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DDRGK PF09756.9 GBG71006.1 - 5.8 6.5 15.1 12 5.4 15.1 1.5 1 0 0 1 1 1 0 DDRGK domain DUF16 PF01519.16 GBG71006.1 - 6.7 7.3 10.9 0.49 10.9 4.3 2.5 1 1 2 3 3 3 0 Protein of unknown function DUF16 AAA_2 PF07724.14 GBG71007.1 - 9.6e-58 195.1 0.5 2.2e-55 187.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) Clp_N PF02861.20 GBG71007.1 - 2.6e-38 129.9 2.8 1.7e-18 66.4 0.3 2.9 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_lid_9 PF17871.1 GBG71007.1 - 1e-35 121.8 1.0 2.6e-35 120.5 1.0 1.7 1 0 0 1 1 1 1 AAA lid domain ClpB_D2-small PF10431.9 GBG71007.1 - 2.2e-24 85.3 0.3 1e-23 83.2 0.3 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GBG71007.1 - 6.9e-24 84.8 0.0 3.6e-13 50.1 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GBG71007.1 - 9.6e-20 71.0 0.4 1.6e-11 44.4 0.0 3.6 2 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG71007.1 - 5.3e-12 46.4 1.9 3.8e-06 27.4 0.5 4.1 3 1 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 GBG71007.1 - 9.6e-09 35.2 0.0 1.6e-05 24.7 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 GBG71007.1 - 7.6e-08 32.0 0.0 4.4e-05 23.0 0.0 3.7 3 1 0 3 3 3 1 Bacterial TniB protein UVR PF02151.19 GBG71007.1 - 1.5e-07 30.9 0.8 1.5e-07 30.9 0.8 2.0 2 0 0 2 2 1 1 UvrB/uvrC motif AAA_22 PF13401.6 GBG71007.1 - 2.3e-07 31.1 3.3 0.015 15.6 0.3 5.1 2 2 1 3 3 2 2 AAA domain IstB_IS21 PF01695.17 GBG71007.1 - 3.8e-07 30.0 0.0 0.0095 15.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 GBG71007.1 - 4.9e-05 23.4 0.1 0.59 10.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 GBG71007.1 - 6.7e-05 22.4 1.0 0.69 9.3 0.0 3.6 3 1 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GBG71007.1 - 7.5e-05 22.4 0.0 0.0057 16.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GBG71007.1 - 8.9e-05 22.8 0.0 0.63 10.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 GBG71007.1 - 0.00011 22.8 6.1 0.18 12.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 GBG71007.1 - 0.00018 21.4 0.0 0.026 14.4 0.0 2.7 3 0 0 3 3 2 1 NACHT domain RsgA_GTPase PF03193.16 GBG71007.1 - 0.00025 21.0 0.0 0.63 9.9 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase ResIII PF04851.15 GBG71007.1 - 0.00028 20.9 0.1 2.7 8.0 0.0 3.5 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 GBG71007.1 - 0.00032 20.0 0.0 0.053 12.8 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin RuvB_N PF05496.12 GBG71007.1 - 0.00033 20.4 0.4 2.6 7.8 0.0 4.1 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 GBG71007.1 - 0.00081 19.7 0.1 3.1 8.0 0.1 3.2 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 GBG71007.1 - 0.0019 17.9 0.1 1.7 8.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 GBG71007.1 - 0.0021 18.0 0.0 0.82 9.7 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GBG71007.1 - 0.0029 17.8 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GBG71007.1 - 0.0043 16.6 0.4 4 6.9 0.0 2.8 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 GBG71007.1 - 0.0051 16.7 0.0 1.1 9.2 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GBG71007.1 - 0.006 16.4 0.0 1.1 9.0 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase III, delta subunit Torsin PF06309.11 GBG71007.1 - 0.0098 16.0 0.0 0.097 12.8 0.0 2.4 2 0 0 2 2 2 1 Torsin ABC_tran PF00005.27 GBG71007.1 - 0.012 16.2 0.0 2.6 8.6 0.0 3.0 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 GBG71007.1 - 0.02 15.1 0.0 3.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GBG71007.1 - 0.024 14.7 0.1 8 6.6 0.1 3.3 3 1 0 3 3 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 GBG71007.1 - 0.072 12.2 0.1 4.7 6.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 GBG71007.1 - 0.072 13.0 0.4 31 4.4 0.0 3.5 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 GBG71007.1 - 0.2 12.2 9.5 0.56 10.7 0.0 3.6 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GBG71007.1 - 0.63 9.9 9.6 5.6 6.8 0.1 4.2 6 0 0 6 6 3 0 ATPase domain predominantly from Archaea RT_RNaseH_2 PF17919.1 GBG71008.1 - 1.4e-27 95.6 0.0 2.4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71008.1 - 3.2e-25 88.4 0.0 5.2e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71008.1 - 8.7e-20 70.6 0.5 3.4e-19 68.7 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG71008.1 - 9.3e-11 42.0 0.0 2.5e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71008.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger GBP PF02263.19 GBG71009.1 - 5e-41 140.7 0.0 7.6e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 GBG71009.1 - 3.9e-07 29.8 0.0 6.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain RHD3 PF05879.12 GBG71009.1 - 0.00021 19.6 0.0 0.00054 18.3 0.0 1.6 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) 3HCDH PF00725.22 GBG71009.1 - 0.16 12.6 0.0 0.38 11.4 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain MMR_HSR1 PF01926.23 GBG71009.1 - 0.17 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RVP_2 PF08284.11 GBG71010.1 - 2.3e-07 30.7 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71010.1 - 7.8e-07 29.7 0.0 1.7e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71010.1 - 0.00017 22.1 0.0 0.00067 20.2 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG71010.1 - 0.0019 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG71010.1 - 0.01 15.6 0.0 0.043 13.6 0.0 2.0 2 1 0 2 2 2 0 Aspartyl protease DUF4392 PF14336.6 GBG71010.1 - 0.059 12.8 0.4 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) ARF7EP_C PF14949.6 GBG71011.1 - 0.39 11.4 3.5 0.18 12.4 0.4 2.1 3 0 0 3 3 3 0 ARF7 effector protein C-terminus zf-C2H2_jaz PF12171.8 GBG71012.1 - 0.0068 16.7 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding NAD_binding_1 PF00175.21 GBG71013.1 - 0.0028 18.3 0.0 0.0049 17.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain HTH_Tnp_ISL3 PF13542.6 GBG71013.1 - 0.047 13.1 0.0 12 5.4 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 RVT_1 PF00078.27 GBG71014.1 - 1.1e-29 103.6 0.1 2e-29 102.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71014.1 - 7e-23 80.6 0.0 1.5e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71014.1 - 8.9e-23 80.6 0.0 1.9e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71014.1 - 1e-17 64.0 0.1 2.2e-17 62.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71014.1 - 4.1e-08 33.4 0.0 1.4e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG71014.1 - 2.6e-06 28.0 0.0 5.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71014.1 - 2.7e-06 27.2 0.0 5.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71014.1 - 1.1e-05 25.9 0.0 2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG71014.1 - 0.00034 20.4 0.0 0.0008 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-H2C2 PF09337.10 GBG71014.1 - 0.0081 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG71014.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG71014.1 - 0.049 13.4 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease CBFD_NFYB_HMF PF00808.23 GBG71017.1 - 4.6e-28 97.3 0.4 6.5e-28 96.8 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GBG71017.1 - 0.00018 21.9 0.0 0.00029 21.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GBG71017.1 - 0.0041 17.2 0.0 0.0054 16.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 GBG71017.1 - 0.043 13.8 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TRM PF02005.16 GBG71018.1 - 1.3e-47 162.8 0.0 2e-39 135.9 0.0 2.2 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Myb_DNA-bind_4 PF13837.6 GBG71018.1 - 5.5e-10 39.5 0.7 1.2e-09 38.4 0.7 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG71018.1 - 0.019 15.2 0.1 0.058 13.7 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG71019.1 - 2.2e-12 46.9 0.0 3.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71019.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein Yippee-Mis18 PF03226.14 GBG71020.1 - 1e-11 45.0 0.2 1.3e-11 44.6 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SMP PF04927.12 GBG71021.1 - 7.6e-15 55.1 0.5 7.6e-15 55.1 0.5 3.7 4 1 1 5 5 5 1 Seed maturation protein DUF1682 PF07946.14 GBG71021.1 - 5.3 6.1 7.8 9.8 5.3 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4637 PF15470.6 GBG71021.1 - 6.9 6.4 13.2 0.22 11.2 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DSPc PF00782.20 GBG71022.1 - 5.3e-27 94.3 0.0 7.7e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 GBG71022.1 - 1.5e-08 34.4 0.0 9.7e-05 22.2 0.0 2.8 2 1 0 2 2 2 2 Gelsolin repeat Y_phosphatase PF00102.27 GBG71022.1 - 0.0089 15.6 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase dCMP_cyt_deam_1 PF00383.23 GBG71025.1 - 3.2e-05 23.8 0.3 0.0038 17.1 0.2 2.9 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GBG71025.1 - 7.8e-05 22.4 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 GBG71025.1 - 0.017 15.2 0.0 0.061 13.4 0.0 2.0 1 0 0 1 1 1 0 Bd3614-like deaminase SPX PF03105.19 GBG71025.1 - 2.9 7.7 8.2 4.1 7.2 2.2 2.1 2 0 0 2 2 2 0 SPX domain Integrase_H2C2 PF17921.1 GBG71026.1 - 1.3e-15 57.2 0.8 6.7e-15 54.9 0.1 2.6 3 1 1 4 4 4 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG71026.1 - 1.6e-12 47.4 0.0 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG71026.1 - 3.9e-10 40.0 0.0 9.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71026.1 - 3.3e-05 24.0 0.0 8.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger ProRS-C_1 PF09180.11 GBG71027.1 - 2e-21 76.0 0.8 4.4e-21 74.9 0.8 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 GBG71027.1 - 9.4e-17 61.5 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GBG71027.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Lactamase_B_4 PF13691.6 GBG71028.1 - 2.4e-16 59.2 0.0 5.2e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 GBG71028.1 - 1.7e-10 40.8 0.1 0.0004 20.0 0.0 3.0 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GBG71028.1 - 0.0033 17.4 5.0 0.004 17.2 0.4 2.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Radial_spoke PF04712.12 GBG71028.1 - 0.57 9.1 7.4 1.5 7.6 7.4 1.6 1 0 0 1 1 1 0 Radial spokehead-like protein Plasmodium_Vir PF05795.11 GBG71029.1 - 0.22 10.9 1.2 0.25 10.7 1.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein YL1 PF05764.13 GBG71029.1 - 0.48 10.5 18.8 0.72 9.9 18.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PTPRCAP PF15713.5 GBG71029.1 - 0.61 10.4 14.8 0.15 12.3 11.5 1.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CDC27 PF09507.10 GBG71029.1 - 0.77 9.1 22.3 1.1 8.6 22.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 GBG71029.1 - 1.2 7.3 11.4 1.8 6.8 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG71029.1 - 8.1 6.2 8.0 12 5.6 8.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.10 GBG71030.1 - 0.037 13.4 14.4 0.045 13.1 14.4 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG71030.1 - 0.15 10.2 13.4 0.17 10.1 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG71030.1 - 0.5 8.6 8.7 0.69 8.1 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG71030.1 - 0.75 9.2 14.4 0.87 8.9 14.4 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG71030.1 - 2.3 6.9 3.3 2.7 6.7 3.3 1.2 1 0 0 1 1 1 0 Presenilin DSPc PF00782.20 GBG71031.1 - 3.5e-25 88.4 0.0 5e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 GBG71031.1 - 0.0021 17.9 0.0 0.17 11.8 0.0 2.8 2 1 0 2 2 2 1 Gelsolin repeat Y_phosphatase PF00102.27 GBG71031.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4637 PF15470.6 GBG71032.1 - 0.027 14.2 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Secretin_N_2 PF07655.13 GBG71032.1 - 0.083 13.4 15.1 0.087 13.4 7.7 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain PGM_PMM_III PF02880.16 GBG71032.1 - 0.16 12.2 0.8 15 5.8 0.1 2.7 2 1 1 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III RNase_H2_suC PF08615.11 GBG71032.1 - 0.93 9.7 5.8 2 8.6 3.5 2.4 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) NOA36 PF06524.12 GBG71032.1 - 5.2 6.3 7.0 7.6 5.8 7.0 1.2 1 0 0 1 1 1 0 NOA36 protein zf-CCHC PF00098.23 GBG71033.1 - 0.00011 22.1 3.0 0.00021 21.2 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG71033.1 - 0.0056 16.6 3.5 0.0056 16.6 3.5 1.7 2 0 0 2 2 2 1 Zinc knuckle DUF5629 PF18629.1 GBG71033.1 - 0.018 15.6 2.3 0.027 15.0 2.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5629) AIF-MLS PF14962.6 GBG71033.1 - 0.087 12.8 7.0 0.12 12.4 7.0 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence zf-CCHC_2 PF13696.6 GBG71033.1 - 0.21 11.4 1.9 0.41 10.5 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle RNA_polI_A34 PF08208.11 GBG71033.1 - 1.4 9.0 11.4 1.7 8.7 11.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ndc1_Nup PF09531.10 GBG71033.1 - 1.4 7.5 3.3 1.6 7.3 3.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4337 PF14235.6 GBG71033.1 - 1.7 8.7 7.3 2.4 8.2 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RPN2_C PF18004.1 GBG71033.1 - 1.8 8.4 7.8 2.7 7.9 7.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 GBG71033.1 - 6.5 6.5 8.5 7.8 6.2 8.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF3g PF12353.8 GBG71033.1 - 8.7 6.8 12.2 11 6.4 3.9 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Trypsin_2 PF13365.6 GBG71034.1 - 8.6e-32 111.1 0.8 2.1e-31 109.8 0.8 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GBG71034.1 - 2.3e-13 50.5 0.1 3.7e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 GBG71034.1 - 0.19 10.3 0.6 0.31 9.6 0.6 1.2 1 0 0 1 1 1 0 Peptidase S46 RVT_1 PF00078.27 GBG71035.1 - 9.9e-36 123.3 0.0 1.5e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71035.1 - 1.1e-30 105.6 0.0 2.5e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71035.1 - 2.7e-22 79.1 0.0 5.8e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Senescence PF06911.12 GBG71036.1 - 0.0069 16.7 9.7 0.13 12.5 2.0 2.4 2 0 0 2 2 2 2 Senescence-associated protein Tmemb_cc2 PF10267.9 GBG71036.1 - 2.5 7.1 3.9 1.2 8.2 0.6 1.8 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Tn7_TnsC_Int PF11426.8 GBG71037.1 - 0.056 13.6 0.8 0.1 12.8 0.8 1.4 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC BSD PF03909.17 GBG71038.1 - 1.3e-11 44.4 0.1 2.2e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 BSD domain Wtap PF17098.5 GBG71040.1 - 0.0092 15.9 1.0 0.013 15.4 1.0 1.2 1 0 0 1 1 1 1 WTAP/Mum2p family DUF4618 PF15397.6 GBG71040.1 - 0.015 14.7 1.4 0.03 13.7 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) KASH_CCD PF14662.6 GBG71040.1 - 0.019 14.8 5.0 0.095 12.5 1.2 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Exonuc_VII_L PF02601.15 GBG71040.1 - 0.056 13.0 0.4 0.062 12.9 0.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fmp27_WPPW PF10359.9 GBG71040.1 - 0.061 12.2 0.5 0.067 12.0 0.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF883 PF05957.13 GBG71040.1 - 0.074 13.7 1.2 0.12 13.0 1.0 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FliT PF05400.13 GBG71040.1 - 0.14 13.0 6.6 0.082 13.7 4.8 1.6 1 1 0 1 1 1 0 Flagellar protein FliT DUF4407 PF14362.6 GBG71040.1 - 0.31 10.4 2.3 0.36 10.1 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 GBG71040.1 - 0.33 8.8 0.4 0.35 8.7 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 GBG71040.1 - 0.33 11.0 3.1 0.62 10.1 3.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PLAC9 PF15205.6 GBG71040.1 - 0.78 10.2 3.1 3.6 8.0 0.2 2.2 1 1 1 2 2 2 0 Placenta-specific protein 9 DUF2570 PF10828.8 GBG71040.1 - 1.1 9.1 3.6 0.25 11.2 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DivIC PF04977.15 GBG71040.1 - 1.5 8.6 6.0 0.59 9.9 0.6 2.3 1 1 1 2 2 2 0 Septum formation initiator MbeD_MobD PF04899.12 GBG71043.1 - 0.085 13.0 0.1 2.9 8.1 0.0 2.8 2 1 1 3 3 3 0 MbeD/MobD like DivIC PF04977.15 GBG71043.1 - 0.14 12.0 5.3 2.6 7.9 0.6 2.6 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 GBG71043.1 - 0.26 11.7 5.1 1.7 9.2 0.1 2.6 2 1 0 2 2 2 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 GBG71043.1 - 2.5 8.4 6.1 1.4 9.2 0.4 2.8 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RT_RNaseH PF17917.1 GBG71044.1 - 3e-26 91.8 0.0 9.5e-26 90.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71044.1 - 1.4e-22 79.6 0.0 5e-22 77.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71044.1 - 5.5e-15 55.2 0.9 5.5e-15 55.2 0.9 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG71044.1 - 9.3e-12 44.9 0.1 2.2e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG71044.1 - 0.00042 20.5 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Es2 PF09751.9 GBG71044.1 - 0.21 11.3 15.7 0.37 10.5 15.7 1.3 1 0 0 1 1 1 0 Nuclear protein Es2 Phage_GPO PF05929.11 GBG71044.1 - 0.26 10.9 0.0 0.26 10.9 0.0 3.1 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase cNMP_binding PF00027.29 GBG71045.1 - 5.6e-06 26.3 0.0 2.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain AAA_23 PF13476.6 GBG71045.1 - 0.92 10.0 13.3 0.73 10.3 6.7 2.6 2 0 0 2 2 2 0 AAA domain DUF1081 PF06448.11 GBG71045.1 - 7.1 7.1 7.0 0.38 11.2 0.9 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1081) CAF1 PF04857.20 GBG71045.1 - 9.2 5.3 7.7 0.41 9.8 1.6 1.9 2 0 0 2 2 2 0 CAF1 family ribonuclease Aminotran_5 PF00266.19 GBG71046.1 - 1e-64 218.9 0.0 1.5e-63 215.0 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GBG71046.1 - 0.00026 20.4 0.1 0.00033 20.0 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Fcf1 PF04900.12 GBG71047.1 - 7.8e-26 90.4 0.0 1.4e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Fcf1 Nucleo_P87 PF07267.11 GBG71047.1 - 0.3 9.9 3.8 0.47 9.2 3.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RVT_1 PF00078.27 GBG71048.1 - 2.2e-06 27.4 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HrpJ PF07201.11 GBG71050.1 - 0.011 16.1 7.8 0.015 15.6 3.8 2.2 1 1 0 2 2 2 0 HrpJ-like domain Novirhabdo_Nv PF05554.11 GBG71050.1 - 0.062 13.1 0.2 5.7 6.7 0.0 2.4 1 1 1 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein YojJ PF10372.9 GBG71050.1 - 1.3 9.1 3.9 0.8 9.8 1.3 2.0 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF5327 PF17261.2 GBG71050.1 - 4.2 8.2 7.1 2.9 8.7 0.5 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5327) ESSS PF10183.9 GBG71051.1 - 3.8e-07 30.3 0.0 4.2e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NAD_binding_8 PF13450.6 GBG71052.1 - 3.9e-05 23.8 1.4 0.00018 21.7 0.7 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG71052.1 - 0.00019 21.2 0.1 0.00034 20.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GBG71052.1 - 0.0013 18.0 0.1 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG71052.1 - 0.0056 17.2 0.8 0.013 16.0 0.8 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GBG71052.1 - 0.0094 16.0 0.7 0.066 13.2 0.3 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GBG71052.1 - 0.031 13.5 1.0 0.052 12.8 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 GBG71052.1 - 0.061 12.6 1.4 0.35 10.1 0.5 2.4 3 0 0 3 3 3 0 Thi4 family Pyr_redox_3 PF13738.6 GBG71052.1 - 0.12 11.6 2.4 0.066 12.5 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GBG71052.1 - 0.15 11.1 2.3 0.26 10.3 2.3 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 GBG71052.1 - 0.34 10.2 4.5 0.4 9.9 2.6 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2167 PF09935.9 GBG71053.1 - 0.19 10.9 0.5 0.4 9.8 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2167) DUF4680 PF15730.5 GBG71053.1 - 0.21 11.9 5.6 0.13 12.6 2.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) DUF659 PF04937.15 GBG71054.1 - 1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Troponin-I_N PF11636.8 GBG71055.1 - 0.014 15.3 1.5 0.014 15.3 1.5 2.5 2 0 0 2 2 2 0 Troponin I residues 1-32 MukE PF04288.13 GBG71057.1 - 0.034 13.1 0.5 0.034 13.1 0.5 1.9 2 0 0 2 2 2 0 MukE-like family DNA_pol_B_palm PF14792.6 GBG71060.1 - 0.063 13.5 0.2 0.4 10.9 0.1 2.3 2 1 1 3 3 3 0 DNA polymerase beta palm DUF287 PF03384.14 GBG71060.1 - 0.093 13.1 0.6 0.28 11.6 0.6 1.8 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 DUF3242 PF11586.8 GBG71061.1 - 0.092 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) zf-U11-48K PF05253.12 GBG71061.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger RT_RNaseH_2 PF17919.1 GBG71062.1 - 1.6e-27 95.4 0.0 3.2e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71062.1 - 9.2e-27 93.4 0.0 1.8e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71062.1 - 3.4e-23 82.3 0.1 5.4e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG71063.1 - 6.8e-30 103.8 0.2 2.3e-27 95.6 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71063.1 - 2.3e-12 47.0 0.0 6e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71063.1 - 0.00029 20.5 0.4 1.6 8.3 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain Esterase PF00756.20 GBG71064.1 - 0.07 12.8 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Putative esterase RVT_1 PF00078.27 GBG71067.1 - 5.2e-30 104.6 0.1 1.1e-29 103.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71067.1 - 8.5e-24 83.9 0.0 2.2e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71067.1 - 1.6e-23 82.6 0.0 3.8e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG71067.1 - 1.1e-08 34.9 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71067.1 - 3.6e-08 33.9 0.0 9.7e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71067.1 - 7.8e-07 29.6 0.0 2.6e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG71067.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG71067.1 - 0.014 15.6 0.0 0.014 15.6 0.0 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein RVP PF00077.20 GBG71067.1 - 0.16 12.3 0.0 0.61 10.4 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF16 PF01519.16 GBG71067.1 - 0.81 10.2 2.3 2.8 8.5 2.3 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF16 ABC1 PF03109.16 GBG71068.1 - 2.6e-29 101.8 0.0 4.3e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 GBG71068.1 - 0.0038 16.8 0.0 0.2 11.2 0.0 2.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 GBG71068.1 - 0.22 11.4 1.1 9.8 6.0 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ribosomal_S21 PF01165.20 GBG71069.1 - 2.6e-19 68.7 9.0 3.7e-19 68.2 9.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 RAP1 PF07218.11 GBG71069.1 - 6.4 4.9 4.8 6.3 5.0 4.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LMBR1 PF04791.16 GBG71070.1 - 0.24 10.3 3.6 0.32 9.8 3.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CSRNP_N PF16019.5 GBG71070.1 - 1.9 8.3 11.4 0.16 11.9 3.0 2.0 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus RNA_pol_3_Rpc31 PF11705.8 GBG71070.1 - 3.5 7.8 20.3 0.028 14.7 9.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Na_H_Exchanger PF00999.21 GBG71072.1 - 3.8e-65 220.1 41.3 4.9e-65 219.8 41.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 GBG71072.1 - 5.1e-20 71.9 0.0 1.2e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain PAXIP1_C PF15364.6 GBG71072.1 - 2.4 8.5 5.3 0.53 10.6 0.3 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein ParA PF10609.9 GBG71073.1 - 3.4e-64 216.7 0.1 9.8e-40 136.5 0.0 2.1 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GBG71073.1 - 5.4e-14 52.3 0.0 1e-13 51.5 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GBG71073.1 - 7.3e-09 35.8 0.1 1.1e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 GBG71073.1 - 1.8e-06 27.5 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 GBG71073.1 - 5.3e-05 22.8 1.5 0.012 15.1 0.0 2.7 3 0 0 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 GBG71073.1 - 0.00017 20.9 0.2 0.0032 16.7 0.2 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 GBG71073.1 - 0.0031 16.8 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein AAA_25 PF13481.6 GBG71073.1 - 0.0032 17.1 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.7 GBG71074.1 - 1.1e-25 90.4 14.0 1.8e-25 89.8 14.0 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 GBG71074.1 - 1e-24 87.6 0.0 2.1e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG71074.1 - 4.2e-11 43.2 0.0 1.1e-06 28.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GBG71074.1 - 0.00031 21.3 0.5 0.00031 21.3 0.5 1.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane PF01061.24 GBG71074.1 - 0.00037 20.0 28.4 0.0018 17.7 18.5 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 GBG71074.1 - 0.0065 15.8 4.6 0.015 14.6 4.6 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_24 PF13479.6 GBG71074.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG71074.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_12 PF13087.6 GBG71075.1 - 3e-57 193.5 0.0 8.2e-57 192.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GBG71075.1 - 6.8e-38 130.9 4.1 5.5e-21 75.5 0.8 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GBG71075.1 - 5.8e-11 42.9 0.5 1.5e-06 28.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 GBG71075.1 - 2.3e-10 40.5 0.4 3.6e-05 23.6 0.1 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 GBG71075.1 - 6.1e-05 22.9 2.2 0.32 10.7 0.0 3.9 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 GBG71075.1 - 0.00061 19.4 0.1 0.063 12.8 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 GBG71075.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 GBG71075.1 - 0.0044 16.3 0.1 0.46 9.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 GBG71075.1 - 0.018 14.9 0.1 0.038 13.8 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Flavi_DEAD PF07652.14 GBG71075.1 - 0.041 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 GBG71075.1 - 0.049 13.9 0.2 0.62 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 GBG71075.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Anti-TRAP PF15777.5 GBG71075.1 - 0.16 12.0 0.7 1 9.4 0.7 2.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein PRIMA1 PF16101.5 GBG71075.1 - 0.62 10.1 3.8 1.6 8.8 3.8 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 GBG71077.1 - 1.7e-37 129.2 0.0 2.2e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71077.1 - 1.3e-33 116.4 0.0 1.7e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG71077.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Epsilon_antitox PF08998.11 GBG71077.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial epsilon antitoxin RVT_1 PF00078.27 GBG71078.1 - 1.3e-35 122.9 0.1 2.1e-35 122.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71078.1 - 1.3e-21 76.5 0.0 2.9e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71078.1 - 1.8e-10 41.0 0.0 4.9e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SelB-wing_1 PF09105.10 GBG71078.1 - 0.079 12.9 1.0 1.9 8.5 0.5 2.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Es2 PF09751.9 GBG71078.1 - 0.1 12.3 12.9 0.16 11.7 12.9 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 FAM76 PF16046.5 GBG71081.1 - 0.00039 19.9 4.1 0.00049 19.5 4.1 1.1 1 0 0 1 1 1 1 FAM76 protein Herpes_BLRF2 PF05812.12 GBG71081.1 - 0.001 19.2 0.2 0.001 19.2 0.2 2.1 2 1 1 3 3 3 1 Herpesvirus BLRF2 protein FlxA PF14282.6 GBG71081.1 - 0.0011 18.9 2.2 1.4 9.0 0.9 2.4 1 1 1 2 2 2 2 FlxA-like protein Filament PF00038.21 GBG71081.1 - 0.013 15.1 2.9 0.019 14.5 2.9 1.3 1 0 0 1 1 1 0 Intermediate filament protein Fez1 PF06818.15 GBG71081.1 - 0.015 15.8 2.2 0.024 15.1 2.2 1.2 1 0 0 1 1 1 0 Fez1 ZapB PF06005.12 GBG71081.1 - 0.019 15.4 13.1 0.62 10.6 1.4 3.8 2 1 1 3 3 3 0 Cell division protein ZapB CorA PF01544.18 GBG71081.1 - 0.047 13.0 1.3 0.074 12.4 1.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIC PF04977.15 GBG71081.1 - 0.26 11.1 9.3 0.062 13.1 2.4 2.9 2 1 1 3 3 3 0 Septum formation initiator KASH_CCD PF14662.6 GBG71081.1 - 0.51 10.1 7.9 0.43 10.4 1.8 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Tup_N PF08581.10 GBG71081.1 - 0.52 10.7 4.9 1.2 9.5 0.1 3.0 1 1 1 2 2 2 0 Tup N-terminal Csm1_N PF18504.1 GBG71081.1 - 0.88 10.0 5.6 2.4 8.6 0.6 3.0 1 1 2 3 3 3 0 Csm1 N-terminal domain FlaC_arch PF05377.11 GBG71081.1 - 1.2 9.6 6.3 4.6 7.7 0.7 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 GBG71081.1 - 1.3 9.0 9.5 0.69 9.9 1.6 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 GBG71081.1 - 2.7 8.1 7.0 8.9 6.5 1.2 3.3 2 1 0 3 3 3 0 TolA binding protein trimerisation TSC22 PF01166.18 GBG71081.1 - 4.9 7.6 6.0 1.5 9.2 0.3 2.8 3 1 0 3 3 3 0 TSC-22/dip/bun family Crr6 PF08847.11 GBG71082.1 - 1.2e-12 47.7 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Chlororespiratory reduction 6 Peptidase_C48 PF02902.19 GBG71083.1 - 3.2e-15 56.6 0.1 5.9e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SPX PF03105.19 GBG71083.1 - 0.74 9.7 10.7 1.3 8.9 10.7 1.3 1 0 0 1 1 1 0 SPX domain BUD22 PF09073.10 GBG71083.1 - 0.8 9.0 15.2 1.3 8.3 15.2 1.2 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.9 GBG71083.1 - 2.4 6.9 5.1 3.6 6.3 5.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Raftlin PF15250.6 GBG71083.1 - 4.5 5.9 7.0 7.3 5.2 7.0 1.3 1 0 0 1 1 1 0 Raftlin Stevor PF17410.2 GBG71083.1 - 5 6.6 5.2 0.47 9.9 0.6 1.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame RNB PF00773.19 GBG71084.1 - 5.4e-71 239.6 0.2 7.9e-49 166.7 0.0 2.2 1 1 1 2 2 2 2 RNB domain OB_Dis3 PF17849.1 GBG71084.1 - 3.1e-19 68.8 0.0 5.9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 GBG71084.1 - 1.1e-15 58.1 1.1 2.2e-15 57.1 1.1 1.6 1 0 0 1 1 1 1 PIN domain Rrp44_CSD1 PF17216.3 GBG71084.1 - 3.7e-09 36.4 0.0 7.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 GBG71084.1 - 5.6e-09 35.9 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 GBG71084.1 - 6.3e-05 23.1 0.0 0.0077 16.4 0.0 2.6 2 0 0 2 2 2 1 Cold shock domain RVT_1 PF00078.27 GBG71085.1 - 8.1e-27 94.2 0.8 1.8e-26 93.0 0.0 2.0 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71085.1 - 9.5e-24 83.3 0.0 3.1e-23 81.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71085.1 - 3.6e-23 81.8 0.0 8.7e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Guanylate_cyc PF00211.20 GBG71085.1 - 1.4e-06 28.1 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Integrase_H2C2 PF17921.1 GBG71085.1 - 0.00014 21.9 0.0 0.00037 20.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain AAA_16 PF13191.6 GBG71085.1 - 0.066 13.6 0.0 0.38 11.1 0.0 2.4 1 0 0 1 1 1 0 AAA ATPase domain Retrotrans_gag PF03732.17 GBG71085.1 - 0.067 13.5 0.0 0.26 11.6 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Cnd3 PF12719.7 GBG71085.1 - 0.068 12.4 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain TPR_2 PF07719.17 GBG71085.1 - 0.16 12.1 5.7 2.1 8.7 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 GBG71085.1 - 0.5 11.2 6.7 3.8 8.4 0.1 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat ATG16 PF08614.11 GBG71085.1 - 2.5 8.3 5.9 7.9 6.7 5.9 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_1 PF00515.28 GBG71085.1 - 2.7 7.9 6.2 0.28 11.1 0.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG71085.1 - 3.2 8.1 5.9 17 5.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG71085.1 - 4.2 8.1 6.7 29 5.4 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG71086.1 - 5e-13 49.1 0.2 1.1e-12 48.0 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG71086.1 - 1.9e-05 25.2 0.0 6.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG71086.1 - 2.1e-05 24.3 0.0 6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71086.1 - 3e-05 24.5 0.0 0.00018 22.0 0.0 2.3 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Bromodomain PF00439.25 GBG71087.1 - 3.6e-36 123.1 0.0 1.1e-17 63.9 0.0 2.5 2 0 0 2 2 2 2 Bromodomain RVT_1 PF00078.27 GBG71088.1 - 8.9e-30 103.8 0.0 1.8e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71088.1 - 5.6e-23 81.2 0.0 1.2e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71088.1 - 3e-22 78.5 0.0 6.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG71088.1 - 1e-07 32.1 0.0 3.1e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG71088.1 - 1.1e-07 32.4 0.0 2.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG71088.1 - 5.1e-07 29.7 2.3 1.2e-06 28.5 2.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG71088.1 - 6.1e-07 29.3 0.0 1.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71088.1 - 1e-05 26.0 0.0 3.1e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG71088.1 - 0.00019 21.2 0.0 0.00048 20.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG71088.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG71088.1 - 0.019 15.2 0.0 0.25 11.6 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein Chromo PF00385.24 GBG71088.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Guanylate_cyc PF00211.20 GBG71089.1 - 0.00013 21.7 0.0 0.00037 20.2 0.0 1.8 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain gag-asp_proteas PF13975.6 GBG71090.1 - 1.1e-06 29.1 0.1 7.6e-06 26.4 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71090.1 - 2e-05 25.1 0.0 0.00011 22.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG71090.1 - 0.0032 17.3 0.2 0.011 15.6 0.2 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71091.1 - 9.5e-07 29.3 0.1 6e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71091.1 - 1.8e-05 25.3 0.0 8.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG71091.1 - 0.0042 16.9 0.2 0.0084 15.9 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease Radical_SAM PF04055.21 GBG71092.1 - 8.7e-16 58.7 0.0 3.4e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 GBG71092.1 - 0.00056 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 GBG71092.1 - 0.0023 18.2 0.1 0.004 17.4 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Ribosomal_L19e PF01280.20 GBG71094.1 - 0.043 13.9 9.0 0.039 14.0 7.9 1.5 1 1 1 2 2 2 0 Ribosomal protein L19e RNA_pol_Rpc4 PF05132.14 GBG71094.1 - 0.082 13.3 11.0 0.1 13.0 11.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 GBG71094.1 - 0.12 10.6 30.2 0.12 10.5 30.2 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG71094.1 - 0.12 10.8 30.4 0.13 10.7 30.4 1.0 1 0 0 1 1 1 0 Mpp10 protein PTPRCAP PF15713.5 GBG71094.1 - 0.13 12.5 34.9 0.16 12.2 34.9 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CobT PF06213.12 GBG71094.1 - 0.21 11.0 30.7 0.22 10.9 30.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GBG71094.1 - 0.25 9.6 27.3 0.26 9.5 27.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF5427 PF10310.9 GBG71094.1 - 0.27 10.1 15.7 0.31 10.0 15.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SpoIIIAH PF12685.7 GBG71094.1 - 0.37 10.6 14.6 0.42 10.4 14.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein BUD22 PF09073.10 GBG71094.1 - 0.47 9.8 29.5 0.51 9.6 29.5 1.0 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 GBG71094.1 - 0.53 10.1 23.2 0.58 9.9 23.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG71094.1 - 0.76 9.1 33.0 0.92 8.9 33.0 1.1 1 0 0 1 1 1 0 SDA1 RNA_polI_A34 PF08208.11 GBG71094.1 - 0.77 9.8 23.9 0.81 9.7 23.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CLN3 PF02487.17 GBG71094.1 - 0.82 8.7 5.2 0.84 8.6 5.2 1.0 1 0 0 1 1 1 0 CLN3 protein SpoIIP PF07454.11 GBG71094.1 - 0.87 9.0 15.2 1 8.8 15.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Spore_coat_CotO PF14153.6 GBG71094.1 - 1 9.3 24.5 1.1 9.1 24.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Paf1 PF03985.13 GBG71094.1 - 1 8.3 34.0 1.2 8.0 34.0 1.2 1 0 0 1 1 1 0 Paf1 DDHD PF02862.17 GBG71094.1 - 1.3 9.1 7.0 1.5 8.9 7.0 1.2 1 0 0 1 1 1 0 DDHD domain SLC12 PF03522.15 GBG71094.1 - 1.4 7.9 7.4 1.4 7.9 7.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 GBG71094.1 - 1.4 8.8 6.7 1.5 8.8 6.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.16 GBG71094.1 - 1.5 8.8 4.6 1.6 8.8 4.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.10 GBG71094.1 - 2 8.7 19.1 2.3 8.5 19.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.12 GBG71094.1 - 2.1 7.6 12.6 2.2 7.6 12.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger FGF-BP1 PF06473.12 GBG71094.1 - 2.3 8.0 12.1 2.5 7.9 12.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) CDC27 PF09507.10 GBG71094.1 - 2.4 7.4 24.6 2.8 7.2 24.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hid1 PF12722.7 GBG71094.1 - 2.8 6.0 11.4 2.9 5.9 11.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIF_alpha PF05793.12 GBG71094.1 - 3.3 6.2 34.0 4.2 5.9 34.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Plasmodium_Vir PF05795.11 GBG71094.1 - 3.5 7.0 12.8 3.8 6.8 12.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DNA_pol_phi PF04931.13 GBG71094.1 - 3.8 5.5 36.0 4 5.4 36.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Connexin PF00029.19 GBG71094.1 - 3.9 7.2 13.5 5.1 6.8 13.5 1.3 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 GBG71094.1 - 3.9 6.1 17.1 4.2 6.0 17.1 1.0 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 GBG71094.1 - 4.3 6.9 13.2 4.6 6.8 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) ALMT PF11744.8 GBG71094.1 - 5.1 5.8 7.3 5.4 5.7 7.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF913 PF06025.12 GBG71094.1 - 5.3 5.9 12.5 5.7 5.8 12.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sec62 PF03839.16 GBG71094.1 - 6.5 6.2 13.2 7.7 6.0 13.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 BORG_CEP PF14957.6 GBG71094.1 - 6.9 7.8 7.8 7.7 7.7 7.8 1.1 1 0 0 1 1 1 0 Cdc42 effector LAP1C PF05609.12 GBG71094.1 - 7.2 5.6 14.2 7.6 5.5 14.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MDM1 PF15501.6 GBG71094.1 - 7.5 5.6 21.5 8.3 5.4 21.5 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Drc1-Sld2 PF11719.8 GBG71094.1 - 7.7 5.9 19.3 9 5.7 19.3 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein NPR3 PF03666.13 GBG71094.1 - 7.7 5.2 15.1 8 5.1 15.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TP53IP5 PF15331.6 GBG71094.1 - 8.3 6.5 10.8 9.2 6.3 10.8 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 GATase PF00117.28 GBG71095.1 - 1.1e-43 149.3 0.1 1.9e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ADK PF00406.22 GBG71095.1 - 5.8e-36 123.9 0.0 1.1e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase CPSase_sm_chain PF00988.22 GBG71095.1 - 1.8e-26 92.5 0.0 3.8e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain AAA_17 PF13207.6 GBG71095.1 - 2.6e-17 63.5 0.0 1.5e-16 61.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain Peptidase_C26 PF07722.13 GBG71095.1 - 5.6e-06 26.3 0.8 5.7e-05 23.0 0.8 2.2 1 1 0 1 1 1 1 Peptidase C26 DNA_pol_B_exo1 PF03104.19 GBG71096.1 - 2.3e-65 220.9 0.0 3.9e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 GBG71096.1 - 4.8e-06 26.4 2.4 6.7e-05 22.7 0.8 3.0 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B PF00136.21 GBG71096.1 - 0.00013 20.8 0.0 0.0075 15.0 0.0 2.5 3 0 0 3 3 3 2 DNA polymerase family B RNase_H_2 PF13482.6 GBG71096.1 - 0.00022 21.3 0.1 0.0016 18.5 0.0 2.5 3 0 0 3 3 3 1 RNase_H superfamily LOH1CR12 PF10158.9 GBG71096.1 - 0.14 12.2 0.2 0.34 10.9 0.2 1.6 1 0 0 1 1 1 0 Tumour suppressor protein DUF1744 PF08490.12 GBG71097.1 - 9.1e-83 278.0 0.0 4e-82 275.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) RT_RNaseH_2 PF17919.1 GBG71097.1 - 2.2e-30 104.6 0.0 4.8e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71097.1 - 5.7e-27 94.1 0.0 1.4e-26 92.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71097.1 - 1.8e-11 44.0 0.2 3.6e-11 43.0 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG71098.1 - 0.0061 17.1 0.1 0.014 16.0 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71098.1 - 0.019 15.6 0.1 0.041 14.5 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG71098.1 - 0.053 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG71098.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG71098.1 - 0.6 10.3 1.9 1.4 9.2 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG71100.1 - 1.1e-81 273.5 1.7 1e-27 97.1 0.0 3.5 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71100.1 - 9e-45 150.8 0.0 3.2e-25 88.1 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG71100.1 - 2.7e-38 131.2 0.0 7.6e-38 129.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG71100.1 - 3.1e-33 114.2 0.0 2.5e-22 79.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG71100.1 - 8.3e-09 35.3 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG71100.1 - 3.3e-08 33.7 0.1 3.6e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain COesterase PF00135.28 GBG71100.1 - 1.6e-07 30.6 0.1 1.6e-07 30.6 0.1 2.1 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GBG71100.1 - 4.5e-07 29.9 0.0 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Asp_protease_2 PF13650.6 GBG71100.1 - 1.8e-05 25.3 0.0 6e-05 23.6 0.0 1.9 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71100.1 - 0.00014 22.3 0.0 0.00034 21.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG71100.1 - 0.0085 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Tho2 PF11262.8 GBG71100.1 - 0.16 11.1 0.0 0.16 11.1 0.0 3.2 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 NinG PF05766.12 GBG71100.1 - 1 9.2 6.3 3.2 7.6 6.3 1.8 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein RT_RNaseH PF17917.1 GBG71101.1 - 6.5e-47 158.2 4.4 7.9e-28 96.8 0.2 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71101.1 - 4.1e-44 148.7 1.4 7.6e-32 109.3 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG71101.1 - 5e-30 104.1 0.5 4.1e-14 52.8 0.0 3.0 3 0 0 3 3 3 2 Integrase core domain RVT_1 PF00078.27 GBG71101.1 - 8.9e-30 103.9 0.1 1.9e-29 102.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71101.1 - 2.9e-19 68.9 0.2 6.9e-19 67.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG71101.1 - 9.2e-05 22.6 0.0 0.00045 20.4 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger NAAA-beta PF15508.6 GBG71101.1 - 0.017 15.4 0.0 16 5.9 0.0 3.8 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Mcp5_PH PF12814.7 GBG71101.1 - 0.064 13.4 3.2 3.1 7.9 0.2 2.5 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PUF PF00806.19 GBG71101.1 - 0.081 12.7 0.2 4.6 7.1 0.0 2.9 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat DUF2497 PF10691.9 GBG71101.1 - 0.1 13.0 2.2 1.1 9.7 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) rve_3 PF13683.6 GBG71101.1 - 0.17 11.7 0.2 13 5.6 0.0 3.1 3 0 0 3 3 3 0 Integrase core domain DUF659 PF04937.15 GBG71103.1 - 1.1e-27 96.8 4.1 1.7e-25 89.6 4.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG71103.1 - 9.2e-26 89.8 0.0 2.8e-25 88.3 0.0 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71103.1 - 4e-20 72.0 0.0 1.2e-19 70.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71103.1 - 5e-14 52.4 0.0 3.8e-13 49.5 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG71103.1 - 1.5e-11 44.7 0.0 8.3e-06 26.3 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71103.1 - 1.5e-11 44.7 0.0 0.00038 21.0 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.10 GBG71103.1 - 8.8e-07 28.8 0.4 0.028 14.2 1.1 2.4 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG71103.1 - 8.5e-05 22.3 0.1 0.00063 19.5 0.0 2.3 2 1 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.20 GBG71103.1 - 0.0067 16.7 0.0 0.39 11.1 0.0 2.7 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-BED PF02892.15 GBG71103.1 - 0.011 15.7 0.2 0.022 14.8 0.2 1.5 1 0 0 1 1 1 0 BED zinc finger AT_hook PF02178.19 GBG71103.1 - 0.26 11.3 6.4 1.4 9.1 6.4 2.4 1 0 0 1 1 1 0 AT hook motif THDPS_N_2 PF14805.6 GBG71103.1 - 1.4 9.2 5.2 0.29 11.4 0.6 2.4 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal RVT_1 PF00078.27 GBG71104.1 - 1e-25 90.6 0.1 1.2e-24 87.1 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71104.1 - 9.1e-25 86.6 0.0 2.2e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71104.1 - 1.9e-15 57.0 0.0 6.1e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG71104.1 - 7e-07 29.8 0.0 2.1e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71104.1 - 4.3e-06 27.2 0.0 1.7e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG71104.1 - 0.0025 17.6 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71104.1 - 0.02 14.6 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG71104.1 - 0.088 13.1 7.8 0.21 11.9 0.1 4.6 4 0 0 4 4 4 0 Retrotransposon gag protein CLZ PF16526.5 GBG71104.1 - 2.3 8.6 7.8 5.6 7.4 2.2 3.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Senescence_reg PF04520.13 GBG71104.1 - 4.2 8.2 8.9 0.95 10.3 4.6 2.1 2 0 0 2 2 2 0 Senescence regulator RT_RNaseH_2 PF17919.1 GBG71105.1 - 1.8e-23 82.5 0.0 3.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71105.1 - 6.1e-21 74.7 0.1 3.9e-20 72.1 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71105.1 - 0.0077 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG71105.1 - 0.016 15.5 0.2 0.084 13.2 0.1 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG71106.1 - 1.1e-21 77.4 0.3 1.9e-21 76.6 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71106.1 - 1.6e-13 50.6 0.1 3.1e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71106.1 - 0.00013 22.2 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71106.1 - 0.00064 19.9 0.2 0.0023 18.1 0.3 1.9 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 GBG71107.1 - 4.2e-30 104.9 0.1 7.2e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) bZIP_2 PF07716.15 GBG71107.1 - 0.02 14.9 2.9 0.083 13.0 2.9 2.1 1 0 0 1 1 1 0 Basic region leucine zipper DUF2385 PF09539.10 GBG71107.1 - 0.097 13.2 0.4 2 9.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) DivIC PF04977.15 GBG71107.1 - 0.39 10.5 2.6 1.4 8.8 2.1 2.2 2 0 0 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 GBG71107.1 - 0.5 10.7 4.7 0.93 9.8 1.0 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain GvpL_GvpF PF06386.11 GBG71107.1 - 0.97 9.3 5.0 2.3 8.1 5.0 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HALZ PF02183.18 GBG71107.1 - 3.4 8.0 6.6 0.34 11.2 1.4 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper RVT_1 PF00078.27 GBG71108.1 - 2.5e-06 27.2 0.0 5e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_LYR PF05347.15 GBG71108.1 - 0.034 14.2 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Cytochrom_B561 PF03188.16 GBG71108.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 CCDC-167 PF15188.6 GBG71109.1 - 9.6 6.6 9.4 2.8 8.4 4.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 MCU PF04678.13 GBG71109.1 - 9.9 6.2 7.5 9.6 6.3 1.9 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Retrotrans_gag PF03732.17 GBG71110.1 - 0.013 15.8 0.5 0.03 14.6 0.2 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein DUF659 PF04937.15 GBG71112.1 - 3.3e-33 114.7 0.0 5.1e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Ribosomal_60s PF00428.19 GBG71112.1 - 0.002 18.7 7.1 0.0049 17.4 7.1 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Senescence_reg PF04520.13 GBG71113.1 - 0.0028 18.5 1.6 0.0028 18.5 1.6 2.5 3 1 0 3 3 3 1 Senescence regulator DUF4680 PF15730.5 GBG71113.1 - 0.044 14.1 0.5 0.044 14.1 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4680) FlaC_arch PF05377.11 GBG71113.1 - 0.066 13.6 1.2 1.6 9.2 1.4 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-CCHC_5 PF14787.6 GBG71113.1 - 0.13 11.9 1.4 0.26 11.0 1.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG71113.1 - 0.34 11.1 4.3 0.63 10.2 4.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Sec8_exocyst PF04048.14 GBG71113.1 - 2.8 7.8 6.8 0.15 11.9 0.3 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Bacillus_HBL PF05791.11 GBG71113.1 - 3.7 7.3 11.0 4.1 7.2 0.1 3.1 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DNA_pol3_delta2 PF13177.6 GBG71114.1 - 5.6e-34 117.3 0.0 1e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 GBG71114.1 - 1.8e-08 34.9 0.0 4.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GBG71114.1 - 7.1e-05 22.6 0.0 0.00023 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GBG71114.1 - 0.00032 20.5 0.0 0.0048 16.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_gamma3 PF12169.8 GBG71114.1 - 0.001 19.0 0.8 0.002 18.1 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase III subunits gamma and tau domain III AAA_5 PF07728.14 GBG71114.1 - 0.0024 17.9 0.0 3.4 7.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG71114.1 - 0.0079 16.6 0.7 0.15 12.4 0.1 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG71114.1 - 0.033 14.5 0.0 0.16 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 GBG71115.1 - 5.3e-34 117.3 0.0 1e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 GBG71115.1 - 1.8e-08 34.9 0.0 4.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GBG71115.1 - 7e-05 22.6 0.0 0.00022 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GBG71115.1 - 0.00032 20.5 0.0 0.0048 16.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_gamma3 PF12169.8 GBG71115.1 - 0.00098 19.0 0.8 0.002 18.1 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase III subunits gamma and tau domain III AAA_5 PF07728.14 GBG71115.1 - 0.0028 17.7 0.0 3.4 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG71115.1 - 0.0077 16.6 0.7 0.15 12.4 0.1 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG71115.1 - 0.032 14.5 0.0 0.16 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain Integrase_H2C2 PF17921.1 GBG71117.1 - 4.9e-13 49.0 0.4 1.1e-12 47.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG71117.1 - 2e-06 28.2 0.1 9.6e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG71117.1 - 0.00024 21.3 0.0 0.00054 20.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG71117.1 - 0.0013 19.4 0.0 0.008 16.8 0.0 2.4 3 0 0 3 3 3 1 Aspartyl protease RVP PF00077.20 GBG71117.1 - 0.0077 16.5 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71117.1 - 0.028 14.2 1.2 0.057 13.2 1.2 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG71117.1 - 0.046 13.9 1.0 0.13 12.5 1.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger ATP-synt PF00231.19 GBG71117.1 - 0.081 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 ATP synthase CENP-N PF05238.13 GBG71117.1 - 0.72 9.1 7.3 2.1 7.6 7.3 1.7 1 0 0 1 1 1 0 Kinetochore protein CHL4 like RVT_1 PF00078.27 GBG71119.1 - 5e-30 104.7 0.1 9.2e-30 103.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG71119.1 - 0.035 14.4 1.5 0.24 11.7 0.2 3.0 2 0 0 2 2 2 0 Retrotransposon gag protein ACC_epsilon PF13822.6 GBG71119.1 - 0.067 13.9 0.5 0.25 12.1 0.5 2.0 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit FmiP_Thoc5 PF09766.9 GBG71119.1 - 5.1 6.3 7.2 1.4 8.1 3.8 1.7 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Aminotran_1_2 PF00155.21 GBG71120.1 - 1.8e-35 122.8 0.0 2.5e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 GBG71120.1 - 0.042 12.6 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 GBG71120.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase zf-CCHC PF00098.23 GBG71121.1 - 1.5e-06 28.0 3.0 4.2e-06 26.6 3.0 1.8 1 0 0 1 1 1 1 Zinc knuckle Prok-RING_1 PF14446.6 GBG71121.1 - 1.3 9.0 5.0 0.84 9.6 1.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-CCHC_2 PF13696.6 GBG71121.1 - 2.6 8.0 8.0 0.3 11.0 2.6 2.1 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG71123.1 - 3.1e-26 92.3 0.1 5.2e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71123.1 - 1.1e-19 70.7 0.1 2.7e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71123.1 - 1.2e-12 47.7 0.0 3e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG71123.1 - 7.5e-12 45.0 0.0 1.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_3 PF13456.6 GBG71123.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like DDE_Tnp_4 PF13359.6 GBG71125.1 - 5.5e-26 91.1 0.0 7.6e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71125.1 - 4.7e-15 55.7 0.0 7.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71125.1 - 4.3e-05 23.2 0.1 0.27 10.9 0.2 2.2 2 0 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG71126.1 - 1.9e-06 28.2 0.8 3.1e-06 27.5 0.3 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG71126.1 - 0.067 13.3 1.0 0.091 12.8 0.1 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG71127.1 - 5.2e-69 232.1 0.3 1.1e-26 93.7 0.0 4.4 4 0 0 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71127.1 - 2e-62 207.5 0.0 8.7e-26 89.9 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71127.1 - 2.7e-53 178.7 0.0 1.2e-24 86.6 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Aminotran_1_2 PF00155.21 GBG71127.1 - 8.8e-23 81.0 0.0 7.8e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II RVP_2 PF08284.11 GBG71127.1 - 1e-10 41.5 0.0 2.6e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71127.1 - 3.6e-09 37.1 0.2 1.5e-07 31.9 0.0 2.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71127.1 - 2e-07 31.5 0.1 8.3e-06 26.3 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG71127.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF2781 PF10914.8 GBG71127.1 - 0.092 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) TRPM_tetra PF16519.5 GBG71127.1 - 3.7 7.7 7.4 8.9 6.5 0.1 4.5 4 0 0 4 4 4 0 Tetramerisation domain of TRPM DUF659 PF04937.15 GBG71128.1 - 3.6e-33 114.6 0.1 7.7e-33 113.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG71128.1 - 5e-27 93.9 0.0 1e-25 89.7 0.0 2.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71128.1 - 2.3e-23 82.5 0.0 6.1e-22 77.9 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71128.1 - 2.7e-10 40.1 0.1 6.4e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG71128.1 - 0.13 11.9 3.7 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase I_LWEQ PF01608.17 GBG71128.1 - 9.6 6.4 13.1 60 3.8 9.3 3.1 3 0 0 3 3 3 0 I/LWEQ domain RT_RNaseH_2 PF17919.1 GBG71129.1 - 2.1e-33 114.3 0.0 5e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71129.1 - 8.3e-29 100.0 0.5 3.1e-28 98.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71129.1 - 1.1e-18 67.1 1.5 2.3e-12 46.9 0.1 2.8 2 1 1 3 3 3 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG71129.1 - 4.2e-17 62.4 0.0 8.3e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG71129.1 - 3.4e-11 43.4 0.0 8.1e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain CHAD PF05235.14 GBG71129.1 - 0.0088 16.0 7.5 0.75 9.7 0.1 2.5 2 0 0 2 2 2 2 CHAD domain Cep57_MT_bd PF06657.13 GBG71129.1 - 0.12 12.9 5.8 0.12 12.8 2.8 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Phage_GPO PF05929.11 GBG71129.1 - 0.22 11.1 7.2 0.48 10.0 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Snapin_Pallidin PF14712.6 GBG71129.1 - 1.9 9.0 8.2 2.5 8.6 0.1 2.8 2 0 0 2 2 2 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 GBG71129.1 - 8.9 5.8 9.2 17 4.9 9.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF659 PF04937.15 GBG71130.1 - 7.7e-13 48.6 0.3 1.4e-12 47.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Gifsy-2 PF13856.6 GBG71131.1 - 0.17 12.3 0.0 0.66 10.4 0.0 1.9 2 0 0 2 2 2 0 ATP-binding sugar transporter from pro-phage gag-asp_proteas PF13975.6 GBG71131.1 - 0.22 12.1 0.1 0.22 12.1 0.1 2.5 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG71131.1 - 0.82 9.9 8.8 0.41 10.8 0.6 2.6 2 0 0 2 2 2 0 Zinc knuckle PTPRCAP PF15713.5 GBG71131.1 - 2.5 8.4 14.3 0.055 13.8 5.5 2.8 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG71131.1 - 9.4 4.4 8.7 16 3.6 8.7 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC PF00098.23 GBG71132.1 - 0.022 14.8 1.8 0.046 13.8 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF684 PF05075.14 GBG71132.1 - 0.03 13.3 2.8 0.15 11.0 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF684) zf-CCHC_2 PF13696.6 GBG71132.1 - 0.14 12.0 1.9 0.27 11.1 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle CaKB PF03185.15 GBG71132.1 - 0.14 11.8 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Rtf2 PF04641.12 GBG71132.1 - 0.2 11.0 12.0 0.41 10.0 3.1 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger DUF5071 PF16804.5 GBG71132.1 - 0.52 10.6 3.0 2.5 8.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) LMBR1 PF04791.16 GBG71132.1 - 2 7.3 3.3 2.5 6.9 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF659 PF04937.15 GBG71133.1 - 2.1e-28 99.1 0.0 3.5e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SAPS PF04499.15 GBG71133.1 - 0.0016 17.3 2.0 0.31 9.8 0.0 2.3 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein Dimer_Tnp_hAT PF05699.14 GBG71133.1 - 0.0016 18.2 0.3 0.003 17.3 0.3 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FYDLN_acid PF09538.10 GBG71133.1 - 0.0066 17.1 2.3 0.0066 17.1 2.3 5.9 5 1 1 6 6 6 2 Protein of unknown function (FYDLN_acid) DDHD PF02862.17 GBG71133.1 - 2.7 8.1 5.8 15 5.6 0.6 3.1 3 0 0 3 3 3 0 DDHD domain RT_RNaseH_2 PF17919.1 GBG71134.1 - 1.2e-21 76.6 0.0 2.2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71134.1 - 1.3e-11 44.7 0.0 2.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71134.1 - 9.4e-11 41.6 0.2 1.4e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71136.1 - 1.3e-11 44.5 0.0 2.7e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG71136.1 - 0.12 12.7 0.1 0.65 10.3 0.1 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein REV PF00424.18 GBG71137.1 - 0.71 9.9 4.7 2.1 8.4 0.2 3.1 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) RT_RNaseH PF17917.1 GBG71138.1 - 2.5e-30 104.9 0.2 1.8e-29 102.1 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71138.1 - 3.6e-29 100.7 0.0 1.3e-28 98.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71138.1 - 1.6e-18 66.5 0.5 4e-18 65.3 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71138.1 - 3e-18 66.1 0.0 7.7e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71138.1 - 0.00055 20.1 0.1 0.0013 18.9 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG71138.1 - 0.039 13.9 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG71138.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) LcrG PF07216.12 GBG71138.1 - 0.16 11.9 0.2 0.36 10.8 0.2 1.5 1 0 0 1 1 1 0 LcrG protein Phage_GPO PF05929.11 GBG71138.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG71139.1 - 6.5e-37 127.2 0.1 6e-27 94.6 0.1 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71139.1 - 5.7e-32 109.7 0.0 1.4e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71139.1 - 1.1e-24 86.7 0.0 2.6e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4399 PF14347.6 GBG71139.1 - 0.049 14.0 0.0 5.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) CSTF2_hinge PF14327.6 GBG71139.1 - 0.13 12.8 0.4 0.46 11.0 0.4 2.0 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 FdhE PF04216.12 GBG71139.1 - 1.2 8.9 5.7 1.8 8.4 2.2 2.4 3 0 0 3 3 3 0 Protein involved in formate dehydrogenase formation RVT_1 PF00078.27 GBG71140.1 - 7.3e-84 280.7 6.4 1.1e-27 97.0 0.6 3.3 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71140.1 - 1.2e-33 115.1 0.4 1.6e-31 108.3 0.1 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71140.1 - 8.2e-29 100.0 0.1 2.2e-28 98.6 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG71140.1 - 1e-09 38.2 0.0 2.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71140.1 - 0.00017 22.1 0.0 0.00098 19.7 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease DUF4168 PF13767.6 GBG71140.1 - 0.0063 17.7 0.4 2.5 9.4 0.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4168) DUF4399 PF14347.6 GBG71140.1 - 0.029 14.7 0.0 25 5.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4399) gag-asp_proteas PF13975.6 GBG71140.1 - 0.03 14.9 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF4140 PF13600.6 GBG71140.1 - 0.52 10.8 6.7 0.17 12.4 2.1 2.7 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) USP8_dimer PF08969.11 GBG71140.1 - 0.68 10.1 2.4 0.69 10.1 0.1 2.3 2 0 0 2 2 2 0 USP8 dimerisation domain rve PF00665.26 GBG71141.1 - 1e-19 70.8 0.0 5.5e-19 68.5 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain GCN5L1 PF06320.13 GBG71141.1 - 0.19 11.9 3.8 0.48 10.6 3.8 1.7 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) RT_RNaseH_2 PF17919.1 GBG71142.1 - 1.9e-30 104.8 0.0 4.7e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71142.1 - 2e-26 92.3 0.0 5.1e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71143.1 - 8.7e-26 90.8 1.4 9.7e-26 90.7 0.3 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71143.1 - 3e-16 59.3 0.0 3.7e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG71143.1 - 3.1e-14 52.8 0.1 7.3e-10 38.8 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG71143.1 - 3.6e-13 49.7 0.0 9.4e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG71143.1 - 3.1e-09 37.0 3.5 0.0073 16.6 0.0 4.1 3 1 1 4 4 4 3 RNase H-like domain found in reverse transcriptase DBINO PF13892.6 GBG71143.1 - 0.0035 17.7 5.6 0.0035 17.7 5.6 3.1 2 0 0 2 2 2 1 DNA-binding domain Retrotrans_gag PF03732.17 GBG71143.1 - 0.046 14.0 0.0 0.18 12.1 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein TPR_11 PF13414.6 GBG71143.1 - 0.047 13.4 0.1 0.17 11.6 0.1 1.9 1 0 0 1 1 1 0 TPR repeat zf-H2C2 PF09337.10 GBG71143.1 - 0.057 13.7 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 GBG71143.1 - 0.13 12.1 0.3 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain rve PF00665.26 GBG71144.1 - 7.6e-10 39.0 0.0 2.1e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG71144.1 - 8.4e-05 23.1 0.0 0.00018 22.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71144.1 - 0.00018 22.0 0.1 0.0005 20.6 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG71144.1 - 0.00031 21.0 0.0 0.0016 18.6 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG71144.1 - 0.0054 16.5 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF2781 PF10914.8 GBG71144.1 - 0.056 13.8 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) RT_RNaseH_2 PF17919.1 GBG71145.1 - 9.3e-52 173.2 0.0 4.6e-32 110.0 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71145.1 - 1.5e-39 134.5 0.1 4e-29 101.0 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71145.1 - 5.9e-34 117.5 0.0 1.4e-16 60.7 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71145.1 - 5e-19 68.2 0.1 1.4e-18 66.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71145.1 - 3.4e-13 49.8 0.0 8.9e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG71145.1 - 2.2e-07 31.3 0.2 1.4e-06 28.7 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71145.1 - 2e-05 25.1 0.0 0.0001 22.9 0.0 2.3 2 0 0 2 2 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG71145.1 - 0.00052 20.2 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG71145.1 - 0.017 14.8 0.0 0.066 12.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Asp_protease PF09668.10 GBG71145.1 - 0.022 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Mitofilin PF09731.9 GBG71145.1 - 0.023 13.6 27.3 0.046 12.6 27.3 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1758 PF05585.12 GBG71145.1 - 0.028 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) AF-4 PF05110.13 GBG71145.1 - 0.19 9.8 23.0 0.28 9.2 23.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SAPS PF04499.15 GBG71145.1 - 2.4 6.9 7.6 4.9 5.8 7.6 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.17 GBG71145.1 - 7.8 6.6 6.7 22 5.1 6.7 1.7 1 0 0 1 1 1 0 DDHD domain RT_RNaseH_2 PF17919.1 GBG71146.1 - 1.5e-32 111.6 0.0 4e-32 110.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71146.1 - 1.6e-29 102.2 0.1 3.5e-29 101.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71146.1 - 4.6e-19 68.3 0.1 1.2e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG71146.1 - 5e-15 55.6 0.0 1.2e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG71146.1 - 3e-13 50.0 0.0 7.7e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG71146.1 - 1.7e-07 31.7 0.2 1.2e-06 28.9 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71146.1 - 2.4e-05 24.9 0.0 8.9e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG71146.1 - 0.00048 20.3 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG71146.1 - 0.016 14.9 0.0 0.057 13.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Asp_protease PF09668.10 GBG71146.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG71146.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) AAA_11 PF13086.6 GBG71146.1 - 2.5 7.8 16.2 5.5 6.7 16.2 1.5 1 0 0 1 1 1 0 AAA domain BSP_II PF05432.11 GBG71146.1 - 5.6 6.6 11.7 11 5.7 11.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TPR_7 PF13176.6 GBG71147.1 - 0.087 12.9 0.0 0.34 11.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat gag-asp_proteas PF13975.6 GBG71148.1 - 5.9e-07 30.0 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71148.1 - 5.9e-05 23.6 0.1 0.00014 22.4 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71148.1 - 0.00077 19.3 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71148.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG71148.1 - 0.0086 15.7 0.1 0.029 14.0 0.3 1.8 2 0 0 2 2 2 1 Topoisomerase I zinc-ribbon-like DUF4992 PF16383.5 GBG71148.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function AAA PF00004.29 GBG71151.1 - 1.4e-97 323.2 0.0 2e-47 160.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG71151.1 - 3.3e-29 100.4 6.9 3.4e-14 52.4 1.2 2.6 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 GBG71151.1 - 4.6e-22 78.0 0.9 1.3e-21 76.5 0.9 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 GBG71151.1 - 3.3e-14 52.9 0.0 1.7e-05 24.6 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 GBG71151.1 - 3.1e-13 49.3 0.0 6.3e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 GBG71151.1 - 7.2e-13 49.0 0.0 2.7e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GBG71151.1 - 4.6e-12 46.6 0.7 0.00034 21.0 0.1 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GBG71151.1 - 3.8e-11 43.4 1.0 0.0043 17.3 0.1 5.2 4 2 1 5 5 4 2 AAA domain AAA_5 PF07728.14 GBG71151.1 - 8.3e-11 42.0 0.1 3.1e-05 24.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GBG71151.1 - 1.1e-10 41.8 0.0 8.3e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 GBG71151.1 - 4e-08 32.8 0.5 0.0015 17.8 0.0 2.6 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_18 PF13238.6 GBG71151.1 - 4.2e-08 33.8 0.0 0.018 15.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GBG71151.1 - 5.5e-08 32.9 0.0 0.006 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GBG71151.1 - 6.4e-07 29.0 0.4 0.031 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GBG71151.1 - 6.9e-07 29.2 0.0 0.049 13.4 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 GBG71151.1 - 1.1e-06 29.0 0.0 0.0052 17.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 GBG71151.1 - 3.3e-06 27.6 0.0 0.015 15.9 0.0 3.0 2 1 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.18 GBG71151.1 - 5.3e-06 26.3 0.0 0.003 17.4 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 GBG71151.1 - 1e-05 25.8 0.0 0.097 12.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain Vps4_C PF09336.10 GBG71151.1 - 1.1e-05 25.3 1.0 0.0031 17.5 0.0 3.6 4 0 0 4 4 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 GBG71151.1 - 1.2e-05 25.0 3.3 0.9 9.1 0.0 4.1 3 2 0 4 4 4 1 AAA domain ATPase_2 PF01637.18 GBG71151.1 - 1.4e-05 25.2 0.2 0.22 11.4 0.0 3.6 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea NACHT PF05729.12 GBG71151.1 - 2.2e-05 24.4 0.2 0.31 10.9 0.0 3.9 3 1 1 4 4 4 1 NACHT domain AAA_17 PF13207.6 GBG71151.1 - 2.6e-05 24.7 0.1 0.34 11.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 GBG71151.1 - 3.5e-05 23.2 0.0 0.17 11.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 GBG71151.1 - 5e-05 22.9 0.0 0.16 11.5 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 GBG71151.1 - 5.2e-05 22.7 1.4 2.5 7.4 0.0 3.8 4 0 0 4 4 4 1 KaiC Sigma54_activat PF00158.26 GBG71151.1 - 6.7e-05 22.6 0.0 0.53 10.0 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 GBG71151.1 - 7e-05 22.8 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 GBG71151.1 - 9.6e-05 21.6 0.0 0.035 13.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 GBG71151.1 - 0.00023 21.1 0.0 0.88 9.4 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_24 PF13479.6 GBG71151.1 - 0.00027 20.7 0.1 0.55 9.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.22 GBG71151.1 - 0.00046 19.4 0.1 0.25 10.5 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain ResIII PF04851.15 GBG71151.1 - 0.00083 19.4 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 GBG71151.1 - 0.00086 19.4 0.0 0.58 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 GBG71151.1 - 0.00096 18.4 0.0 0.092 11.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 GBG71151.1 - 0.0013 18.7 3.6 3.2 7.6 0.0 4.9 4 1 0 5 5 5 1 NTPase AAA_3 PF07726.11 GBG71151.1 - 0.0017 18.2 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 GBG71151.1 - 0.0026 18.1 0.8 7.5 6.9 0.1 3.7 3 1 0 4 4 3 0 AAA domain DUF2075 PF09848.9 GBG71151.1 - 0.003 16.8 0.0 2.4 7.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 GBG71151.1 - 0.0041 17.1 0.0 0.8 9.6 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain PhoH PF02562.16 GBG71151.1 - 0.0052 16.3 2.5 2.2 7.7 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein UFD1 PF03152.14 GBG71151.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin2 PF13189.6 GBG71151.1 - 0.013 15.6 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family PduV-EutP PF10662.9 GBG71151.1 - 0.028 14.2 0.0 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cytidylate_kin PF02224.18 GBG71151.1 - 0.031 14.0 0.0 7.6 6.2 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 GBG71151.1 - 0.032 14.3 0.6 8.7 6.4 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase AAA_30 PF13604.6 GBG71151.1 - 0.035 13.8 0.3 13 5.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.6 GBG71151.1 - 0.035 13.9 0.4 7 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 GBG71151.1 - 0.035 13.2 0.0 11 5.0 0.0 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_29 PF13555.6 GBG71151.1 - 0.038 13.7 0.0 7 6.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 GBG71151.1 - 0.1 11.8 0.0 1.7 7.8 0.0 2.6 2 1 0 3 3 3 0 KAP family P-loop domain Zot PF05707.12 GBG71151.1 - 0.13 11.9 0.0 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_23 PF13476.6 GBG71151.1 - 0.23 12.0 1.8 16 5.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain PCNA_C PF02747.15 GBG71152.1 - 0.2 11.9 0.0 0.35 11.0 0.0 1.4 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, C-terminal domain Pyr_redox PF00070.27 GBG71153.1 - 0.023 15.2 0.0 0.032 14.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YqzE PF14038.6 GBG71153.1 - 4 7.5 8.0 5.8 7.0 8.0 1.3 1 0 0 1 1 1 0 YqzE-like protein Myb_DNA-bind_4 PF13837.6 GBG71154.1 - 0.023 15.1 0.9 1.1 9.6 0.1 2.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Sec16_N PF12935.7 GBG71154.1 - 0.036 14.2 2.5 0.074 13.2 2.5 1.4 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus DDE_Tnp_4 PF13359.6 GBG71155.1 - 1.1e-26 93.4 0.0 2.5e-26 92.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71155.1 - 7.5e-14 51.8 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71155.1 - 0.00072 19.3 0.2 0.0025 17.5 0.0 1.9 2 0 0 2 2 2 1 Transposase DDE domain LRAT PF04970.13 GBG71156.1 - 1.8e-24 86.5 0.0 4.8e-24 85.1 0.0 1.8 1 1 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 GBG71156.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 NlpC/P60 family GRP PF07172.11 GBG71157.1 - 0.056 14.1 17.5 0.077 13.7 17.5 1.2 1 0 0 1 1 1 0 Glycine rich protein family Paf1 PF03985.13 GBG71157.1 - 7 5.5 7.2 8 5.3 7.2 1.0 1 0 0 1 1 1 0 Paf1 RVT_1 PF00078.27 GBG71158.1 - 3.3e-22 79.1 0.1 4.6e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG71158.1 - 1.3e-07 32.2 0.0 2.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71158.1 - 5.8e-07 30.0 0.0 1.2e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG71158.1 - 6e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71158.1 - 0.00037 20.3 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG71159.1 - 2.5e-08 33.6 2.8 4.4e-08 32.8 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Fzo_mitofusin PF04799.13 GBG71159.1 - 0.013 15.1 4.4 0.013 15.1 4.4 2.0 1 1 1 2 2 2 0 fzo-like conserved region DUF1943 PF09172.11 GBG71159.1 - 0.23 10.7 4.9 0.33 10.1 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) LMBR1 PF04791.16 GBG71159.1 - 6.8 5.5 8.1 10 4.9 8.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Nop14 PF04147.12 GBG71160.1 - 0.78 7.9 20.9 0.93 7.6 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG71160.1 - 4.1 6.7 21.9 5.1 6.4 21.9 1.1 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.10 GBG71160.1 - 6.8 7.0 9.9 10 6.4 9.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF778 PF05608.12 GBG71161.1 - 4.7e-07 30.4 0.0 4.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF778) AWS PF17907.1 GBG71161.1 - 0.034 14.2 3.6 0.071 13.1 3.6 1.6 1 1 0 1 1 1 0 AWS domain SOSSC PF15925.5 GBG71162.1 - 3.2e-09 38.0 0.3 5e-09 37.4 0.3 1.3 1 0 0 1 1 1 1 SOSS complex subunit C Pox_F11 PF04943.12 GBG71163.1 - 0.014 14.5 0.1 0.022 13.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein DNA_pol_B_palm PF14792.6 GBG71163.1 - 0.091 13.0 0.3 3.9 7.7 0.0 3.0 2 1 1 3 3 3 0 DNA polymerase beta palm SAWADEE PF16719.5 GBG71164.1 - 9.7e-34 116.4 1.9 1.6e-33 115.7 1.9 1.3 1 0 0 1 1 1 1 SAWADEE domain Homeodomain PF00046.29 GBG71164.1 - 0.025 14.4 0.1 0.025 14.4 0.1 1.8 2 0 0 2 2 2 0 Homeodomain CDC27 PF09507.10 GBG71166.1 - 0.19 11.1 32.1 0.29 10.5 32.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MctB PF11382.8 GBG71166.1 - 1.2 8.8 6.7 0.33 10.6 1.9 2.1 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB Bud13 PF09736.9 GBG71166.1 - 3.1 8.2 27.9 2.1 8.7 1.4 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex EBV-NA3 PF05009.12 GBG71166.1 - 3.4 7.1 5.8 8.2 5.9 5.8 1.7 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF4481 PF14800.6 GBG71166.1 - 5.7 6.3 14.7 0.085 12.3 7.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) RVT_1 PF00078.27 GBG71167.1 - 3.3e-31 108.5 0.1 5.9e-31 107.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WES_acyltransf PF03007.16 GBG71167.1 - 0.023 14.5 0.1 0.068 12.9 0.1 1.8 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Chromo PF00385.24 GBG71167.1 - 0.025 14.5 0.1 0.096 12.6 0.0 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG71167.1 - 1 9.6 5.1 1.9 8.8 3.0 2.6 1 1 1 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG71168.1 - 4.3e-23 82.0 0.1 7.8e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71168.1 - 1.1e-17 63.8 0.3 2.9e-17 62.5 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG71168.1 - 7.7e-07 29.6 0.0 2e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG71168.1 - 8.9e-07 28.8 0.0 2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71168.1 - 5.8e-06 26.9 0.0 1.7e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG71168.1 - 0.0018 18.5 0.0 0.0018 18.5 0.0 3.9 5 0 0 5 5 5 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG71168.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG71168.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Flot PF15975.5 GBG71168.1 - 0.13 12.4 5.0 0.3 11.3 5.0 1.6 1 0 0 1 1 1 0 Flotillin SURF6 PF04935.12 GBG71168.1 - 2.6 7.8 12.3 4.8 6.9 12.3 1.3 1 0 0 1 1 1 0 Surfeit locus protein 6 Ion_trans PF00520.31 GBG71169.1 - 0.0032 16.7 10.3 0.0032 16.7 10.3 2.1 2 0 0 2 2 2 1 Ion transport protein DUF1676 PF07898.13 GBG71169.1 - 0.02 14.9 0.1 0.02 14.9 0.1 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1676) Orf78 PF06024.12 GBG71169.1 - 0.3 11.4 5.5 0.62 10.4 0.5 3.5 3 0 0 3 3 3 0 Orf78 (ac78) DHHC PF01529.20 GBG71169.1 - 3.9 7.6 6.1 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase RT_RNaseH_2 PF17919.1 GBG71170.1 - 8.6e-22 77.1 0.0 2.2e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71170.1 - 6.4e-19 68.2 0.2 1.3e-18 67.2 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71170.1 - 4.2e-10 39.5 0.1 7.7e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG71170.1 - 3.1e-05 24.1 0.1 0.21 11.8 0.0 2.5 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG71171.1 - 0.0042 16.6 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) WASH-7_mid PF14744.6 GBG71173.1 - 1.3e-125 419.1 0.0 2.1e-125 418.4 0.0 1.3 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_N PF14745.6 GBG71173.1 - 1.2e-85 288.1 0.0 3.7e-85 286.6 0.0 1.7 1 1 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 GBG71173.1 - 2.1e-46 157.8 0.0 4.7e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal SET PF00856.28 GBG71173.1 - 4e-10 40.3 0.0 2e-09 38.1 0.0 2.3 1 0 0 1 1 1 1 SET domain Cullin PF00888.22 GBG71174.1 - 5.4e-182 606.7 8.9 6.4e-182 606.4 8.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GBG71174.1 - 8.4e-26 89.8 2.9 2.5e-25 88.3 2.9 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain zf-CCHC PF00098.23 GBG71175.1 - 5.6e-24 83.1 65.4 1.4e-05 24.9 0.7 8.4 8 0 0 8 8 8 6 Zinc knuckle zf-CCHC_4 PF14392.6 GBG71175.1 - 0.0093 15.7 49.6 0.084 12.6 0.7 7.9 7 1 1 8 8 8 5 Zinc knuckle LRR_8 PF13855.6 GBG71176.1 - 5.2e-19 67.8 16.9 2.1e-07 30.6 0.1 4.7 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 GBG71176.1 - 8e-18 64.2 22.9 7e-05 23.1 0.1 5.8 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG71176.1 - 9.3e-09 34.7 12.3 0.076 13.6 0.1 8.7 8 1 0 8 8 8 1 Leucine Rich Repeat SDA1 PF05285.12 GBG71176.1 - 0.043 13.2 39.7 0.06 12.8 39.7 1.1 1 0 0 1 1 1 0 SDA1 LRR_6 PF13516.6 GBG71176.1 - 1.5 9.1 11.2 9.2 6.6 0.0 5.0 7 0 0 7 7 7 0 Leucine Rich repeat FAM176 PF14851.6 GBG71176.1 - 2.5 7.8 0.0 2.5 7.8 0.0 3.5 2 1 0 2 2 2 0 FAM176 family SKG6 PF08693.10 GBG71176.1 - 2.6 7.5 6.0 4.7 6.7 6.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase PF00069.25 GBG71177.1 - 1.7e-39 135.8 0.0 2e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71177.1 - 1.2e-38 132.9 0.0 2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GBG71177.1 - 0.02 13.8 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PIP49_C PF12260.8 GBG71177.1 - 0.038 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 GBG71177.1 - 0.15 12.0 0.5 2.9 7.8 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family RVT_1 PF00078.27 GBG71179.1 - 8.2e-14 51.6 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PGK PF00162.19 GBG71181.1 - 1.9e-160 533.9 0.1 2.5e-160 533.6 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase Hydrolase PF00702.26 GBG71181.1 - 0.0052 17.1 0.1 0.52 10.6 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Topo_Zn_Ribbon PF08272.11 GBG71183.1 - 0.05 13.3 0.3 0.17 11.6 0.3 2.0 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG71183.1 - 0.1 12.7 2.3 0.28 11.3 2.3 1.9 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG71184.1 - 3.6e-08 33.2 0.0 5.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG71184.1 - 1.4e-07 32.0 0.1 5.6e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71184.1 - 3.6e-05 24.3 0.0 0.00011 22.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71184.1 - 0.0051 16.6 0.9 0.011 15.6 0.2 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG71184.1 - 0.19 12.1 0.0 0.53 10.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG71185.1 - 1.3e-20 73.8 0.1 2.8e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG71185.1 - 4.5e-05 23.3 0.0 8.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG71185.1 - 0.086 12.6 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Macoilin PF09726.9 GBG71185.1 - 0.59 8.6 2.5 0.86 8.1 2.5 1.1 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 GBG71186.1 - 8.8e-13 48.5 2.7 9.4e-07 29.4 0.0 4.7 5 1 1 6 6 6 3 WD domain, G-beta repeat RT_RNaseH_2 PF17919.1 GBG71187.1 - 5.5e-11 42.4 0.0 1.4e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71187.1 - 4.7e-10 39.4 0.0 8.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71187.1 - 4.5e-09 36.5 0.0 1.2e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_5 PF14787.6 GBG71187.1 - 0.088 12.5 0.4 0.17 11.6 0.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Bap31_Bap29_C PF18035.1 GBG71187.1 - 0.91 9.6 8.6 0.33 11.0 4.9 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain rve PF00665.26 GBG71188.1 - 5e-08 33.1 0.0 1.3e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG71188.1 - 0.00057 19.9 2.4 0.0012 18.9 2.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Tudor-knot PF11717.8 GBG71188.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG71188.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FAM76 PF16046.5 GBG71188.1 - 0.092 12.1 8.4 0.13 11.6 6.8 1.9 2 0 0 2 2 2 0 FAM76 protein TAF4 PF05236.14 GBG71188.1 - 0.16 11.7 10.6 0.33 10.6 10.6 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-CCHC PF00098.23 GBG71190.1 - 2.6e-07 30.4 3.0 2.6e-07 30.4 3.0 2.1 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG71190.1 - 0.041 13.8 0.7 0.14 12.2 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle Haem_bd PF14376.6 GBG71190.1 - 0.34 10.8 0.1 0.34 10.8 0.1 1.9 2 1 0 2 2 2 0 Haem-binding domain zf-CCHC_2 PF13696.6 GBG71190.1 - 0.42 10.5 6.4 0.11 12.3 2.8 1.8 2 0 0 2 2 2 0 Zinc knuckle KCNQC3-Ank-G_bd PF11956.8 GBG71190.1 - 1.9 8.8 5.9 0.36 11.1 0.9 2.1 1 1 2 3 3 3 0 Ankyrin-G binding motif of KCNQ2-3 zf-CCHC_4 PF14392.6 GBG71190.1 - 6.3 6.6 5.9 0.65 9.8 1.2 1.8 2 0 0 2 2 2 0 Zinc knuckle TMEM247 PF15444.6 GBG71191.1 - 0.005 16.9 0.3 0.011 15.8 0.0 1.6 2 0 0 2 2 2 1 Transmembrane protein 247 Glyoxalase_4 PF13669.6 GBG71192.1 - 2.7e-06 27.6 0.1 0.0066 16.7 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 GBG71192.1 - 0.00012 22.3 0.1 0.0026 17.9 0.0 2.8 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase PF00903.25 GBG71192.1 - 0.0012 19.0 0.2 0.01 16.0 0.0 2.3 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 GBG71192.1 - 0.096 12.8 0.5 1.4 9.0 0.0 2.6 3 1 0 3 3 3 0 Glyoxalase-like domain HSP70 PF00012.20 GBG71193.1 - 9.8e-261 866.2 14.1 1.1e-260 866.0 14.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG71193.1 - 6.2e-20 71.3 3.1 1.6e-17 63.4 0.3 2.8 1 1 1 2 2 2 2 MreB/Mbl protein DUF2096 PF09869.9 GBG71193.1 - 0.035 14.2 0.7 0.099 12.7 0.7 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) FGGY_C PF02782.16 GBG71193.1 - 0.046 13.4 0.2 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 GBG71193.1 - 1.1 8.5 5.7 0.42 9.8 0.1 2.9 3 1 1 4 4 4 0 StbA protein SRP54 PF00448.22 GBG71194.1 - 1.4e-67 227.1 0.0 2.3e-67 226.4 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain RT_RNaseH_2 PF17919.1 GBG71194.1 - 7.3e-29 99.8 0.0 1.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71194.1 - 5.4e-25 87.7 0.0 1e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71194.1 - 2.3e-12 46.8 0.6 5.4e-12 45.6 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain SRP54_N PF02881.19 GBG71194.1 - 5.6e-09 36.1 0.2 1.6e-08 34.6 0.2 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain RVT_1 PF00078.27 GBG71194.1 - 1.2e-08 34.7 0.0 3.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_22 PF13401.6 GBG71194.1 - 0.0041 17.4 0.2 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GBG71194.1 - 0.014 15.1 0.7 0.028 14.2 0.7 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GBG71194.1 - 0.02 14.2 0.1 0.058 12.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 GBG71194.1 - 0.052 13.9 0.1 0.19 12.1 0.1 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 GBG71194.1 - 0.059 13.8 0.0 0.059 13.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 GBG71194.1 - 0.12 12.3 1.3 4 7.3 1.4 2.7 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 GBG71194.1 - 1.5 9.3 4.7 1.5 9.3 0.1 3.0 3 1 0 3 3 3 0 ABC transporter TFIIE_alpha PF02002.17 GBG71195.1 - 1.8e-07 30.9 1.5 2.7e-05 24.0 0.5 2.5 2 0 0 2 2 2 2 TFIIE alpha subunit rve PF00665.26 GBG71195.1 - 0.00087 19.5 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_20 PF12840.7 GBG71195.1 - 0.0055 16.7 0.7 0.015 15.4 0.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4458 PF14660.6 GBG71195.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) GntR PF00392.21 GBG71195.1 - 0.47 10.2 2.4 0.57 9.9 0.5 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF659 PF04937.15 GBG71196.1 - 1.7e-19 70.2 0.1 3.2e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) TPH PF13868.6 GBG71197.1 - 8.3e-25 87.0 95.6 8.3e-25 87.0 95.6 2.3 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Acetyltransf_18 PF18014.1 GBG71197.1 - 3.3 7.5 10.6 0.16 11.8 1.1 3.0 1 1 1 3 3 3 0 Acetyltransferase (GNAT) domain zf-CCHC PF00098.23 GBG71198.1 - 0.00017 21.5 2.4 0.00017 21.5 2.4 2.5 3 0 0 3 3 3 1 Zinc knuckle TAXi_N PF14543.6 GBG71200.1 - 1.8e-33 116.3 0.8 2.4e-33 115.9 0.8 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GBG71200.1 - 4.3e-12 46.1 0.3 1.9e-11 44.0 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease RT_RNaseH_2 PF17919.1 GBG71201.1 - 9.9e-25 86.5 0.0 2.5e-24 85.2 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71201.1 - 1.2e-23 83.4 0.0 2.2e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG71201.1 - 1.6e-06 28.3 0.0 6.1e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_4 PF13359.6 GBG71203.1 - 1.6e-25 89.6 0.0 2.6e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71203.1 - 1.1e-07 31.7 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71203.1 - 0.0093 15.6 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG71204.1 - 1.1e-09 38.6 2.1 1.8e-09 37.8 2.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG71204.1 - 0.01 16.1 0.4 0.02 15.2 0.4 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG71204.1 - 0.069 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain RVT_1 PF00078.27 GBG71205.1 - 1.7e-13 50.6 0.0 2.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG71205.1 - 0.062 11.5 16.1 0.082 11.1 16.1 1.0 1 0 0 1 1 1 0 Nop14-like family Bud13 PF09736.9 GBG71205.1 - 0.84 10.0 9.7 1.3 9.4 9.7 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Presenilin PF01080.17 GBG71205.1 - 3.5 6.3 6.9 5.5 5.6 6.9 1.2 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GBG71205.1 - 3.9 6.7 16.3 5.4 6.2 16.3 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG71205.1 - 5.3 6.4 21.0 7.4 5.9 21.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG71205.1 - 5.5 5.2 14.8 7.5 4.7 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG71205.1 - 7.9 4.4 22.8 11 4.0 22.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4360 PF14273.6 GBG71206.1 - 2.7e-36 125.1 0.0 3.1e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RVT_1 PF00078.27 GBG71207.1 - 1.1e-29 103.6 0.0 2.8e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71207.1 - 3.1e-25 88.1 0.0 8.1e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71207.1 - 4.8e-24 84.6 0.0 1.2e-23 83.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HisKA PF00512.25 GBG71207.1 - 6.1e-17 61.4 2.1 2.2e-16 59.6 0.1 3.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 GBG71207.1 - 1.3e-10 41.8 0.1 6.3e-05 23.5 0.1 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Myb_DNA-bind_4 PF13837.6 GBG71207.1 - 1.2e-09 38.4 1.5 4.6e-09 36.6 1.5 2.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RVP_2 PF08284.11 GBG71207.1 - 3e-08 33.5 0.0 6.8e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71207.1 - 1e-07 32.5 0.0 2.7e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71207.1 - 5.2e-06 26.9 0.0 1.5e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease MADF_DNA_bdg PF10545.9 GBG71207.1 - 0.00084 19.6 1.4 0.0038 17.5 0.4 2.6 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like CDC45 PF02724.14 GBG71207.1 - 0.0011 17.3 8.8 0.0011 17.3 8.8 3.2 3 0 0 3 3 3 2 CDC45-like protein Myb_DNA-bind_5 PF13873.6 GBG71207.1 - 0.0031 17.5 1.1 0.015 15.3 1.1 2.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Asp_protease PF09668.10 GBG71207.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG71207.1 - 0.051 13.8 0.1 0.051 13.8 0.1 3.6 4 0 0 4 4 3 0 Retrotransposon gag protein FAM76 PF16046.5 GBG71207.1 - 0.11 11.8 4.5 0.21 10.9 4.5 1.4 1 0 0 1 1 1 0 FAM76 protein TMEM154 PF15102.6 GBG71207.1 - 0.14 12.1 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 1 0 TMEM154 protein family DUF3877 PF12993.7 GBG71207.1 - 0.15 11.9 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) RVT_1 PF00078.27 GBG71208.1 - 3.4e-16 59.4 0.1 1.3e-15 57.5 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG71208.1 - 1.1e-06 29.1 0.0 4.5e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71208.1 - 1.2e-06 28.3 0.0 4.8e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Response_reg PF00072.24 GBG71208.1 - 0.0016 18.6 0.1 0.0043 17.2 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain gag-asp_proteas PF13975.6 GBG71208.1 - 0.0022 18.5 0.0 0.0077 16.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG71208.1 - 0.013 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG71208.1 - 0.013 15.7 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG71209.1 - 2.8e-18 65.8 0.3 5.9e-18 64.7 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Response_reg PF00072.24 GBG71209.1 - 1.2e-11 44.8 0.1 2e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain zf-H2C2 PF09337.10 GBG71209.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG71210.1 - 5.3e-36 124.2 0.1 9.3e-36 123.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71210.1 - 7.1e-30 103.4 0.9 2.1e-29 101.9 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71210.1 - 1.9e-29 101.6 0.0 9.7e-29 99.4 0.0 2.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71210.1 - 9.2e-15 54.5 0.3 2.2e-14 53.3 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG71210.1 - 0.0037 17.4 2.3 0.0063 16.7 0.1 2.6 3 0 0 3 3 3 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG71210.1 - 0.62 9.6 0.0 0.62 9.6 0.0 3.3 2 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase BAF1_ABF1 PF04684.13 GBG71210.1 - 2.2 7.2 12.8 3.4 6.6 12.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SHIPPO-rpt PF07004.12 GBG71211.1 - 4.6e-10 39.9 14.2 0.15 13.0 0.3 5.5 5 0 0 5 5 5 5 Sperm-tail PG-rich repeat Spc7 PF08317.11 GBG71212.1 - 0.047 12.6 22.9 0.16 10.8 5.9 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein WD40_alt PF14077.6 GBG71212.1 - 0.34 10.8 5.7 1.4 8.8 1.3 3.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif PRKG1_interact PF15898.5 GBG71212.1 - 0.54 11.2 25.8 0.69 10.9 6.9 3.3 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF465 PF04325.13 GBG71212.1 - 2.9 8.0 11.4 1.3 9.1 2.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Fzo_mitofusin PF04799.13 GBG71212.1 - 5.8 6.5 9.5 0.36 10.4 0.3 2.9 2 1 1 3 3 3 0 fzo-like conserved region ADIP PF11559.8 GBG71212.1 - 8.9 6.4 22.1 0.78 9.8 3.8 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Myb_DNA-bind_4 PF13837.6 GBG71213.1 - 2.1e-09 37.6 0.5 6.2e-09 36.1 0.3 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG71213.1 - 0.11 12.9 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG71214.1 - 2.3e-32 111.9 0.0 3.9e-32 111.1 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71214.1 - 1.1e-13 51.3 0.0 1.6e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71214.1 - 0.0027 17.4 0.0 2.2 7.8 0.1 2.3 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG71214.1 - 0.06 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain HATPase_c PF02518.26 GBG71216.1 - 1.6e-22 80.1 0.0 7e-21 74.8 0.0 2.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GBG71216.1 - 7.2e-21 74.4 0.5 1.8e-20 73.2 0.3 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GBG71216.1 - 6.8e-17 61.3 0.1 1.5e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain YkuD_2 PF13645.6 GBG71216.1 - 0.03 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain HisKA PF00512.25 GBG71217.1 - 1.3e-17 63.5 0.1 2.9e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Humanin PF15040.6 GBG71217.1 - 0.29 10.6 1.3 0.54 9.7 1.3 1.5 1 0 0 1 1 1 0 Humanin family Response_reg PF00072.24 GBG71218.1 - 4.1e-21 75.3 0.5 1.1e-20 73.9 0.3 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 GBG71218.1 - 2.5e-18 66.6 0.1 7.4e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YkuD_2 PF13645.6 GBG71218.1 - 0.018 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain REV PF00424.18 GBG71219.1 - 0.66 10.0 7.4 0.97 9.5 0.5 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) TssO PF17561.2 GBG71219.1 - 3.1 7.9 8.6 5.8 7.0 8.6 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF383 PF04063.14 GBG71219.1 - 5.6 6.6 6.9 13 5.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF383) Ceramidase_alk PF04734.13 GBG71220.1 - 8e-10 38.0 0.0 0.0082 14.8 0.0 3.8 3 1 0 3 3 3 3 Neutral/alkaline non-lysosomal ceramidase, N-terminal DUF2070 PF09843.9 GBG71220.1 - 0.00073 18.0 0.0 0.0012 17.2 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) RT_RNaseH PF17917.1 GBG71221.1 - 8.9e-45 151.3 9.5 1e-24 86.8 0.1 4.3 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71221.1 - 9.3e-33 112.1 0.3 5.9e-15 55.1 0.0 4.0 3 0 0 3 3 3 2 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG71221.1 - 3.9e-30 103.8 0.0 6.2e-19 67.9 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Response_reg PF00072.24 GBG71221.1 - 7.1e-20 71.3 0.6 1.6e-19 70.1 0.6 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GBG71221.1 - 2.4e-19 69.9 0.0 3.1e-09 37.3 0.0 3.3 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase rve PF00665.26 GBG71221.1 - 5.1e-11 42.8 0.6 1.5e-08 34.8 0.0 2.9 3 0 0 3 3 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG71221.1 - 1.4e-08 34.8 0.0 3.8e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 H2C2 zinc finger RVT_3 PF13456.6 GBG71221.1 - 0.012 15.4 0.1 4.6 7.1 0.0 3.9 4 0 0 4 4 4 0 Reverse transcriptase-like DUF1942 PF09167.11 GBG71221.1 - 0.025 14.5 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) Phage_GPO PF05929.11 GBG71221.1 - 0.084 12.5 16.6 1.2 8.7 0.1 3.5 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DRY_EERY PF09750.9 GBG71221.1 - 1.5 9.1 11.5 13 6.0 0.0 3.8 3 0 0 3 3 2 0 Alternative splicing regulator Integrase_H2C2 PF17921.1 GBG71222.1 - 5.8e-17 61.6 0.2 1.6e-16 60.2 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71222.1 - 1.4e-10 41.4 0.0 3.7e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG71222.1 - 5.8e-06 26.5 0.4 1.2e-05 25.5 0.4 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NHase_beta PF02211.15 GBG71222.1 - 0.042 13.9 0.1 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Nitrile hydratase beta subunit DUF659 PF04937.15 GBG71223.1 - 5.6e-28 97.7 0.0 5.6e-27 94.5 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71223.1 - 0.0066 16.2 0.1 0.018 14.8 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf_C2H2_6 PF18450.1 GBG71223.1 - 0.072 12.8 0.4 0.25 11.1 0.4 1.9 1 0 0 1 1 1 0 Zinc Finger domain Efg1 PF10153.9 GBG71223.1 - 0.53 10.7 7.4 2 8.8 7.4 2.1 1 0 0 1 1 1 0 rRNA-processing protein Efg1 Myb_DNA-bind_4 PF13837.6 GBG71224.1 - 2.8e-07 30.8 1.9 5.9e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Dsh_C PF12316.8 GBG71224.1 - 0.024 15.1 1.5 0.028 14.8 0.0 1.8 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal MADF_DNA_bdg PF10545.9 GBG71224.1 - 0.15 12.4 2.8 0.46 10.8 0.0 2.5 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVT_1 PF00078.27 GBG71225.1 - 3.4e-26 92.1 0.1 6.9e-26 91.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71225.1 - 1e-22 80.4 0.1 2.2e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71225.1 - 1.9e-16 59.9 0.2 5.5e-16 58.4 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG71225.1 - 1.3e-15 57.3 0.0 3.1e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG71225.1 - 1.3e-14 54.5 0.0 2.8e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG71226.1 - 1.4e-22 79.9 0.0 3.4e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71226.1 - 5.4e-21 74.5 0.0 1.2e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71226.1 - 3.9e-18 65.3 0.6 9.3e-18 64.1 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG71226.1 - 2.6e-07 30.4 0.0 4.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG71226.1 - 0.002 18.3 0.1 0.0039 17.4 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG71226.1 - 0.0084 16.4 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG71226.1 - 0.01 15.9 2.5 0.029 14.4 2.5 1.7 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG71227.1 - 2.9e-29 101.0 0.0 5e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71227.1 - 1.3e-26 92.9 0.0 2.2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71227.1 - 3.3e-18 66.0 0.0 5.3e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG71227.1 - 0.004 16.9 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4746 PF15928.5 GBG71227.1 - 0.73 9.2 13.1 1.1 8.6 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Vfa1 PF08432.10 GBG71227.1 - 1.7 9.0 5.7 2.6 8.4 5.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HATPase_c PF02518.26 GBG71228.1 - 1e-14 55.0 0.0 6.1e-10 39.6 0.0 3.4 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase rve PF00665.26 GBG71228.1 - 9.2e-11 42.0 0.0 2.9e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HisKA PF00512.25 GBG71228.1 - 2.1e-10 40.5 0.1 6.5e-10 38.9 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Chromo PF00385.24 GBG71228.1 - 0.0058 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG71228.1 - 0.013 15.8 0.1 0.067 13.5 0.1 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein Herpes_BLRF2 PF05812.12 GBG71228.1 - 0.093 12.9 0.3 0.32 11.1 0.3 2.0 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF1826 PF08856.11 GBG71228.1 - 7.5 6.4 8.0 3.4 7.5 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1826) Response_reg PF00072.24 GBG71229.1 - 3.9e-05 23.8 0.0 0.00012 22.2 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain RVT_1 PF00078.27 GBG71230.1 - 8e-21 74.6 0.0 1.5e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG71230.1 - 5.4e-17 62.2 0.0 2.4e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG71230.1 - 6.3e-17 61.6 0.0 2.4e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71230.1 - 1.4e-13 51.2 0.0 1.2e-05 25.7 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG71230.1 - 2.2e-06 27.8 1.7 4.8e-05 23.5 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain Asp_protease PF09668.10 GBG71230.1 - 4.2e-05 23.3 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.20 GBG71230.1 - 6.7e-05 23.1 0.0 0.57 10.5 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease AMP-binding_C_2 PF14535.6 GBG71230.1 - 0.0055 17.0 0.0 6.6 7.1 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain FAM76 PF16046.5 GBG71230.1 - 0.28 10.5 24.2 1 8.7 6.2 2.3 2 0 0 2 2 2 0 FAM76 protein DUF4596 PF15363.6 GBG71230.1 - 1 9.6 5.5 7.5 6.9 0.8 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) LEA_3 PF03242.13 GBG71230.1 - 1.2 9.9 10.6 8.3 7.2 0.0 4.1 4 0 0 4 4 4 0 Late embryogenesis abundant protein YrbL-PhoP_reg PF10707.9 GBG71230.1 - 2.6 7.5 7.8 6.2 6.3 0.7 2.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF3573 PF12097.8 GBG71230.1 - 2.7 6.7 4.7 4.2 6.1 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Matrilin_ccoil PF10393.9 GBG71230.1 - 3.1 7.7 11.4 10 6.1 2.0 3.0 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Casc1_N PF15927.5 GBG71230.1 - 6.8 6.3 34.1 8 6.1 13.1 2.5 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus NDUFB11 PF17250.2 GBG71231.1 - 7.4e-36 122.7 0.3 9.8e-36 122.3 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase 11 kDa subunit SAE2 PF08573.10 GBG71231.1 - 0.004 18.2 0.1 0.0058 17.7 0.1 1.2 1 0 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus zf-CCHC PF00098.23 GBG71232.1 - 0.0076 16.3 2.5 0.014 15.4 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG71232.1 - 0.028 14.7 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG71233.1 - 1.7e-47 159.5 0.0 1.2e-28 99.1 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71233.1 - 9.3e-37 125.5 0.1 6.5e-29 100.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71233.1 - 1.5e-19 70.4 0.4 3.6e-15 56.1 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG71233.1 - 6.5e-10 39.2 1.9 0.0028 17.9 0.1 5.2 4 0 0 4 4 4 2 Retrotransposon gag protein zf-CCHC PF00098.23 GBG71233.1 - 1.7e-05 24.6 3.2 4.5e-05 23.3 3.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG71233.1 - 0.04 13.7 4.1 0.087 12.7 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG71234.1 - 1.4e-20 73.7 0.0 2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) BUD22 PF09073.10 GBG71234.1 - 0.00029 20.3 12.5 0.00041 19.8 12.5 1.1 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 GBG71234.1 - 0.15 11.5 17.1 0.22 10.9 17.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG71234.1 - 0.22 9.7 13.4 0.29 9.3 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG71234.1 - 5.2 5.0 26.8 7.1 4.6 26.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Herpes_UL32 PF06070.11 GBG71235.1 - 0.24 9.1 2.2 0.41 8.3 2.2 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DNA_pol_phi PF04931.13 GBG71235.1 - 1.7 6.6 7.3 2.6 6.0 7.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi HATPase_c PF02518.26 GBG71236.1 - 8.9e-12 45.5 0.1 1.3e-11 44.9 0.1 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RVT_1 PF00078.27 GBG71237.1 - 6.3e-21 74.9 0.0 1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71237.1 - 1.3e-19 70.1 0.2 2.4e-19 69.2 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71237.1 - 1.2e-07 32.0 0.0 2.9e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG71237.1 - 8.2e-05 23.2 0.0 0.00015 22.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71237.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71237.1 - 0.0022 18.5 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG71237.1 - 0.0083 16.3 0.0 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 H2C2 zinc finger Response_reg PF00072.24 GBG71238.1 - 1.9e-20 73.1 0.4 2.9e-20 72.5 0.4 1.3 1 0 0 1 1 1 1 Response regulator receiver domain VCBS PF13517.6 GBG71239.1 - 2.3e-14 53.7 17.5 0.0001 22.8 1.3 6.5 2 2 7 9 9 9 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GBG71239.1 - 1.6e-11 44.1 24.8 0.0092 16.1 1.1 6.7 6 0 0 6 6 6 4 FG-GAP repeat Itfg2 PF15907.5 GBG71239.1 - 2.4e-06 26.8 4.2 4.8 6.1 0.1 5.8 5 1 1 6 6 6 3 Integrin-alpha FG-GAP repeat-containing protein 2 PQQ_3 PF13570.6 GBG71239.1 - 7.4e-06 26.3 8.1 0.38 11.3 0.1 5.7 6 0 0 6 6 6 3 PQQ-like domain BBS2_Mid PF14783.6 GBG71239.1 - 1.9e-05 24.7 1.7 0.48 10.5 0.1 5.0 5 1 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 GBG71239.1 - 2.8e-05 23.8 0.3 0.0045 16.6 0.6 2.7 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 GBG71239.1 - 0.0044 16.9 4.7 0.93 9.5 0.0 5.0 5 0 0 5 5 5 1 PQQ enzyme repeat Tachylectin PF14517.6 GBG71239.1 - 0.0051 16.4 0.7 0.45 10.0 0.1 2.9 3 1 0 3 3 3 1 Tachylectin RVT_1 PF00078.27 GBG71240.1 - 1.8e-28 99.5 0.0 3.3e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG71240.1 - 9.5e-12 44.7 0.0 1.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain VasL PF12486.8 GBG71241.1 - 0.00082 19.3 0.1 0.0017 18.2 0.1 1.5 1 0 0 1 1 1 1 Type VI secretion system, EvfB, or VasL HTH_Tnp_1 PF01527.20 GBG71241.1 - 0.021 15.1 0.5 0.021 15.1 0.5 3.6 4 0 0 4 4 4 0 Transposase OmpH PF03938.14 GBG71241.1 - 0.032 14.6 0.6 0.032 14.6 0.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) KASH_CCD PF14662.6 GBG71241.1 - 0.034 14.0 0.8 0.034 14.0 0.8 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH COMP PF11598.8 GBG71241.1 - 0.064 13.7 5.3 2.4 8.7 1.1 2.7 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Fib_alpha PF08702.10 GBG71241.1 - 0.18 12.0 5.5 0.21 11.8 0.5 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 GBG71241.1 - 5.3 7.6 11.3 20 5.7 0.6 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF1192 PF06698.11 GBG71241.1 - 7.4 6.7 15.4 6.1 7.0 0.7 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) Efg1 PF10153.9 GBG71241.1 - 9 6.7 11.3 0.63 10.4 2.2 2.4 2 0 0 2 2 2 0 rRNA-processing protein Efg1 Protocadherin PF08374.11 GBG71242.1 - 0.094 12.7 4.5 0.18 11.7 4.5 1.4 1 0 0 1 1 1 0 Protocadherin PEX11 PF05648.14 GBG71242.1 - 0.32 10.4 1.5 0.57 9.6 1.5 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF4192 PF13830.6 GBG71242.1 - 4 7.4 6.4 6 6.8 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) C_GCAxxG_C_C PF09719.10 GBG71242.1 - 8.2 6.7 7.7 31 4.9 4.3 2.3 2 1 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Prenylcys_lyase PF07156.14 GBG71243.1 - 1.6e-77 261.1 0.0 2.1e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 GBG71243.1 - 4.7e-10 39.3 0.0 6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Glycohydro_20b2 PF14845.6 GBG71243.1 - 0.098 13.3 0.0 0.16 12.7 0.0 1.3 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like DUF659 PF04937.15 GBG71245.1 - 3.5e-25 88.7 0.1 7e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71245.1 - 4.9e-06 26.2 0.1 9.6e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NAD_binding_8 PF13450.6 GBG71246.1 - 2.6e-16 59.6 7.7 7.6e-09 35.7 0.9 3.3 4 0 0 4 4 4 2 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GBG71246.1 - 1.6e-15 57.4 0.9 1.2e-06 28.2 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 GBG71246.1 - 5.6e-09 36.0 6.4 0.00059 19.5 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GBG71246.1 - 1e-05 25.6 0.8 0.17 11.9 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GBG71246.1 - 0.00033 20.0 2.1 0.41 9.8 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GBG71246.1 - 0.0032 16.8 0.8 1.9 7.7 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain MCRA PF06100.11 GBG71246.1 - 0.0044 15.9 5.8 0.43 9.3 0.5 2.1 2 0 0 2 2 2 2 MCRA family SH3_13 PF18335.1 GBG71246.1 - 0.014 15.3 0.0 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain RexB PF15968.5 GBG71246.1 - 0.035 14.6 0.4 10 6.6 0.0 2.5 2 0 0 2 2 2 0 Membrane-anchored ion channel, Abi component Pyr_redox PF00070.27 GBG71246.1 - 0.037 14.6 4.1 6.4 7.4 0.3 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GBG71246.1 - 0.52 9.5 3.6 12 5.0 0.3 2.4 2 0 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 GBG71246.1 - 0.6 10.1 2.7 20 5.1 0.2 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RVT_1 PF00078.27 GBG71247.1 - 2.1e-30 105.9 0.3 7e-30 104.2 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71247.1 - 3.2e-22 78.4 0.0 7e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71247.1 - 4.9e-22 78.2 0.0 1.1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71247.1 - 8.8e-14 51.4 0.0 2.6e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG71247.1 - 0.0064 16.7 0.2 0.041 14.2 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein Integrin_b_cyt PF08725.11 GBG71247.1 - 0.069 12.8 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain zf-CCHC_3 PF13917.6 GBG71249.1 - 0.0025 17.7 1.6 0.0054 16.7 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle rve PF00665.26 GBG71250.1 - 2.4e-14 53.5 0.0 1.8e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG71250.1 - 0.021 14.9 0.6 0.039 14.1 0.6 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain DUF1564 PF07600.11 GBG71250.1 - 0.069 12.8 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Myb_DNA-bind_4 PF13837.6 GBG71252.1 - 1.8e-09 37.9 0.5 7.3e-08 32.7 0.3 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG71252.1 - 0.0063 16.6 1.6 0.018 15.1 1.6 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TraT PF05818.12 GBG71252.1 - 0.13 12.0 0.3 0.32 10.7 0.3 1.6 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DDE_Tnp_4 PF13359.6 GBG71253.1 - 1.6e-31 109.1 0.0 3.6e-31 108.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71253.1 - 6.5e-14 52.0 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71253.1 - 0.0037 17.0 0.3 3.3 7.3 0.1 2.7 3 0 0 3 3 3 2 Transposase DDE domain RT_RNaseH PF17917.1 GBG71254.1 - 1.9e-28 98.8 0.0 3.6e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71254.1 - 2.2e-23 82.2 0.1 9.2e-11 41.7 0.0 3.3 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71254.1 - 3.6e-15 56.1 0.1 4.9e-14 52.4 0.1 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71254.1 - 6.4e-15 55.0 2.0 1.4e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG71254.1 - 6e-05 23.2 0.0 0.00021 21.5 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger F-box-like PF12937.7 GBG71254.1 - 0.00012 21.9 0.3 0.00035 20.4 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG71254.1 - 0.07 13.0 3.2 0.25 11.2 0.1 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 GBG71255.1 - 0.00069 19.5 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG71255.1 - 0.0024 17.7 0.0 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 F-box domain CPSF100_C PF13299.6 GBG71255.1 - 0.072 13.3 1.5 0.13 12.5 1.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 GBG71255.1 - 0.098 10.9 7.2 0.13 10.5 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 GBG71255.1 - 0.19 10.9 12.6 0.26 10.4 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.12 GBG71255.1 - 0.85 8.1 18.7 1.3 7.6 18.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 GBG71255.1 - 2.4 6.3 14.0 3.1 5.9 14.0 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG71255.1 - 2.4 6.8 4.7 3.5 6.3 4.7 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 GBG71255.1 - 7.1 5.3 6.4 9.4 4.9 6.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4637 PF15470.6 GBG71255.1 - 8.4 6.1 15.6 17 5.1 15.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Med15_fungi PF05397.12 GBG71256.1 - 0.032 14.5 0.5 0.095 13.0 0.5 1.8 1 0 0 1 1 1 0 Mediator complex subunit 15 Ppx-GppA PF02541.16 GBG71256.1 - 0.093 12.2 0.7 0.53 9.7 0.5 2.1 2 0 0 2 2 2 0 Ppx/GppA phosphatase family HHH_8 PF14716.6 GBG71256.1 - 0.44 10.9 3.3 0.21 12.0 0.3 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain SOAR PF16533.5 GBG71256.1 - 3.6 7.6 11.4 7.9 6.5 2.7 3.2 3 1 1 4 4 4 0 STIM1 Orai1-activating region DUF4407 PF14362.6 GBG71256.1 - 4.4 6.6 11.3 0.59 9.4 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Herpes_UL6 PF01763.16 GBG71256.1 - 6.4 5.2 8.8 0.39 9.2 2.1 1.9 1 1 0 2 2 2 0 Herpesvirus UL6 like Prp19 PF08606.11 GBG71256.1 - 7.4 6.6 6.7 17 5.5 0.3 3.6 3 1 0 3 3 3 0 Prp19/Pso4-like Occludin_ELL PF07303.13 GBG71256.1 - 9.1 7.1 7.0 0.64 10.8 1.0 2.0 2 0 0 2 2 2 0 Occludin homology domain ABC_tran_Xtn PF12848.7 GBG71256.1 - 9.5 6.3 12.9 1.2 9.3 1.1 2.7 2 0 0 2 2 2 0 ABC transporter MerR-DNA-bind PF09278.11 GBG71256.1 - 9.8 6.8 10.7 0.34 11.5 2.2 2.6 2 0 0 2 2 2 0 MerR, DNA binding Pkinase PF00069.25 GBG71257.1 - 1.5e-13 50.7 0.0 3e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71257.1 - 2.6e-06 26.9 0.0 1.1e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 GBG71257.1 - 0.12 12.8 0.5 1.2 9.6 0.5 2.5 1 1 1 2 2 2 0 HEAT repeats Cnd3 PF12719.7 GBG71257.1 - 0.14 11.3 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 GBG71257.1 - 2.1 8.9 5.1 8.9 6.9 0.2 3.4 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 GBG71258.1 - 0.095 13.1 0.7 0.99 9.8 0.6 2.6 2 1 1 3 3 3 0 HEAT repeats Cnd3 PF12719.7 GBG71258.1 - 0.12 11.5 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 GBG71258.1 - 1.3 9.4 5.1 7.5 7.1 0.2 3.4 3 0 0 3 3 3 0 HEAT repeat RVT_1 PF00078.27 GBG71259.1 - 8.3e-26 90.9 0.1 1.3e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71259.1 - 4.4e-13 49.1 1.5 1.3e-12 47.6 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG71259.1 - 5.2e-12 45.5 0.0 1.2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG71259.1 - 8e-11 42.2 0.0 2.5e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71259.1 - 2.1e-05 24.7 0.0 6.3e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Mito_carr PF00153.27 GBG71260.1 - 2.5e-69 229.3 3.1 1.7e-24 85.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DLH PF01738.18 GBG71261.1 - 0.00094 18.8 0.1 0.0097 15.5 0.1 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family RVT_1 PF00078.27 GBG71262.1 - 3.6e-31 108.4 0.0 4.8e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71262.1 - 1.3e-21 76.5 0.0 3.4e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71262.1 - 5.5e-12 45.9 0.0 2.3e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase F-box-like PF12937.7 GBG71263.1 - 6.1e-06 26.0 0.7 1.4e-05 24.9 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG71263.1 - 0.0076 16.1 0.3 0.017 15.0 0.3 1.5 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 GBG71263.1 - 0.09 13.2 3.8 0.21 12.1 0.1 3.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 GBG71264.1 - 1.8e-06 27.7 0.1 3.6e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG71264.1 - 0.013 15.3 0.1 0.036 13.9 0.1 1.7 1 0 0 1 1 1 0 F-box domain CDC45 PF02724.14 GBG71265.1 - 0.077 11.3 8.3 0.095 11.0 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG71265.1 - 0.078 11.2 6.6 0.091 11.0 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG71265.1 - 0.2 11.3 7.0 0.31 10.7 7.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CRT10 PF08728.10 GBG71265.1 - 0.22 9.6 0.1 0.26 9.4 0.1 1.0 1 0 0 1 1 1 0 CRT10 SDA1 PF05285.12 GBG71265.1 - 0.35 10.3 7.8 0.42 10.0 7.8 1.1 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 GBG71265.1 - 0.38 10.7 12.5 0.5 10.3 12.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 GBG71267.1 - 0.044 13.2 8.6 0.056 12.9 8.6 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG71267.1 - 0.12 12.0 9.4 0.19 11.5 9.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG71267.1 - 0.31 9.3 8.3 0.34 9.2 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG71267.1 - 0.97 7.6 14.2 1.2 7.3 14.2 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 GBG71267.1 - 8.3 5.5 6.5 11 5.1 6.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Myb_DNA-bind_4 PF13837.6 GBG71268.1 - 2.2e-05 24.7 1.6 4e-05 23.9 1.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG71270.1 - 1.4e-30 106.5 0.1 2.7e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71270.1 - 1.4e-29 102.0 0.0 3.9e-29 100.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71270.1 - 3.2e-28 98.1 0.0 9.8e-28 96.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG71270.1 - 8.5e-07 28.8 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71270.1 - 1.1e-05 26.0 0.0 2.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71270.1 - 0.00053 20.5 0.2 0.0025 18.3 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG71270.1 - 0.0084 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Arc_PepC_II PF06847.11 GBG71270.1 - 1.9 9.0 6.4 33 5.1 1.1 4.3 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II Pkinase PF00069.25 GBG71271.1 - 3.2e-18 66.1 0.0 9.1e-18 64.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71271.1 - 4.7e-17 62.1 0.0 9.1e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG71271.1 - 6.2e-05 23.7 0.2 6.2e-05 23.7 0.2 3.9 4 0 0 4 4 3 1 WD domain, G-beta repeat DUF1664 PF07889.12 GBG71271.1 - 0.011 15.7 5.7 0.011 15.7 5.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4164 PF13747.6 GBG71271.1 - 0.012 15.9 8.2 0.012 15.9 8.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) CEP63 PF17045.5 GBG71271.1 - 0.012 15.5 20.5 0.021 14.7 20.5 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DELLA PF12041.8 GBG71271.1 - 0.049 13.5 1.0 13 5.8 0.0 3.5 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal DUF812 PF05667.11 GBG71271.1 - 0.094 11.6 16.0 0.14 11.0 16.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FapA PF03961.13 GBG71271.1 - 0.18 10.4 8.5 0.26 9.8 8.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A IFT57 PF10498.9 GBG71271.1 - 0.31 10.0 12.8 0.52 9.2 12.8 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SH3BP5 PF05276.14 GBG71271.1 - 0.46 10.3 13.2 0.78 9.5 13.2 1.3 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Troponin PF00992.20 GBG71271.1 - 0.49 10.7 26.6 0.3 11.4 11.8 2.4 1 1 1 2 2 2 0 Troponin DUF2730 PF10805.8 GBG71271.1 - 2 8.6 4.5 7.9 6.6 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) AAA_13 PF13166.6 GBG71271.1 - 2.5 6.6 14.7 0.86 8.2 4.2 1.9 1 1 1 2 2 2 0 AAA domain ATG16 PF08614.11 GBG71271.1 - 2.8 8.1 23.3 9.1 6.4 21.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) XhlA PF10779.9 GBG71271.1 - 3.8 7.8 7.4 0.7 10.1 2.1 2.5 1 1 3 4 4 4 0 Haemolysin XhlA YabA PF06156.13 GBG71271.1 - 3.9 8.2 10.0 0.26 11.9 1.6 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 GBG71271.1 - 4 6.9 9.7 7.2 6.1 9.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TTKRSYEDQ PF10212.9 GBG71271.1 - 4.1 6.3 13.7 6.2 5.7 13.7 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF3584 PF12128.8 GBG71271.1 - 6.2 4.2 17.9 8.7 3.7 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 GBG71271.1 - 7.2 7.1 7.8 2.4 8.6 0.5 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 GBG71271.1 - 8.8 7.1 14.4 0.19 12.5 3.8 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Sigma70_ner PF04546.13 GBG71272.1 - 0.83 9.5 0.0 0.83 9.5 0.0 2.9 2 1 0 2 2 2 0 Sigma-70, non-essential region BUD22 PF09073.10 GBG71272.1 - 6.1 6.1 12.5 8.1 5.7 12.5 1.3 1 0 0 1 1 1 0 BUD22 AC_N PF16214.5 GBG71272.1 - 8 5.5 5.2 13 4.7 5.2 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region UL17 PF17640.2 GBG71273.1 - 0.72 9.9 2.9 7.7 6.6 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized UL17 Sigma70_ner PF04546.13 GBG71273.1 - 0.89 9.4 7.6 1.7 8.5 7.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 GBG71273.1 - 1.8 6.5 20.5 2.9 5.9 20.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 GBG71273.1 - 5.4 5.3 11.9 9.3 4.6 11.9 1.3 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG71273.1 - 5.8 5.0 10.3 9.9 4.2 10.3 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 GBG71273.1 - 9.4 6.3 19.6 0.54 10.3 10.7 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Pkinase PF00069.25 GBG71274.1 - 1.3e-17 64.1 0.0 2.4e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71274.1 - 1.2e-15 57.5 0.0 2.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG71274.1 - 5.3e-11 42.9 4.1 2.5e-05 24.9 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG71274.1 - 0.011 16.0 0.1 0.15 12.4 0.1 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG71274.1 - 0.019 13.7 0.3 1.3 7.6 0.0 2.8 4 0 0 4 4 4 0 Nucleoporin Nup120/160 DUF1664 PF07889.12 GBG71274.1 - 0.33 11.0 6.6 0.15 12.1 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 GBG71274.1 - 0.34 9.8 2.4 0.53 9.1 2.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Dfp1_Him1_M PF08630.10 GBG71274.1 - 0.56 10.4 4.3 5.1 7.3 0.7 3.2 3 0 0 3 3 3 0 Dfp1/Him1, central region Matrilin_ccoil PF10393.9 GBG71274.1 - 1.5 8.8 7.7 1.9 8.4 2.6 3.2 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Exonuc_VII_L PF02601.15 GBG71274.1 - 7.2 6.1 8.6 13 5.2 8.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF659 PF04937.15 GBG71275.1 - 1.9e-19 70.0 0.0 2.7e-10 40.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) CHAT PF12770.7 GBG71276.1 - 1.3e-38 133.1 0.0 8.9e-21 74.5 0.0 2.3 2 0 0 2 2 2 2 CHAT domain BUD22 PF09073.10 GBG71277.1 - 2.5 7.3 11.7 3.2 7.0 11.7 1.2 1 0 0 1 1 1 0 BUD22 WD40 PF00400.32 GBG71278.1 - 5.7e-14 52.3 2.5 6.6e-05 23.6 0.1 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat zf-C4H2 PF10146.9 GBG71278.1 - 0.00094 19.5 4.2 0.0015 18.9 4.2 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein Nup160 PF11715.8 GBG71278.1 - 0.0049 15.6 0.2 0.27 9.8 0.0 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 EzrA PF06160.12 GBG71278.1 - 0.0065 14.7 2.8 0.0089 14.2 2.8 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA APG6_N PF17675.1 GBG71278.1 - 0.026 15.1 5.9 0.043 14.3 5.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Calici_PP_N PF08405.11 GBG71278.1 - 0.1 11.4 0.1 0.14 11.0 0.1 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal ANAPC4_WD40 PF12894.7 GBG71278.1 - 0.12 12.7 0.0 7.2 7.0 0.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CENP-K PF11802.8 GBG71278.1 - 0.14 11.7 4.1 0.21 11.2 4.1 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF4404 PF14357.6 GBG71278.1 - 0.2 12.3 2.1 0.52 11.0 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) IKBKB_SDD PF18397.1 GBG71278.1 - 0.27 10.5 5.4 0.39 10.0 5.4 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain DHR10 PF18595.1 GBG71278.1 - 0.3 11.1 9.6 0.71 9.9 9.5 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Prominin PF05478.11 GBG71278.1 - 0.54 8.1 3.9 0.74 7.7 3.9 1.0 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 GBG71278.1 - 0.65 10.1 5.6 1.4 8.9 5.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Ceramidase_alk PF04734.13 GBG71279.1 - 9.4e-140 466.6 0.0 1.5e-139 465.9 0.0 1.3 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 GBG71279.1 - 5.3e-47 159.8 0.0 8.9e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Pkinase PF00069.25 GBG71281.1 - 1.8e-20 73.4 0.1 2.1e-18 66.6 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71281.1 - 5e-20 71.9 0.0 1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG71281.1 - 1e-10 42.0 4.7 1.3e-06 29.0 0.1 4.2 5 0 0 5 5 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG71281.1 - 0.0013 19.0 0.0 0.083 13.2 0.1 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HSBP1 PF06825.12 GBG71281.1 - 0.04 13.8 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Heat shock factor binding protein 1 TPR_MLP1_2 PF07926.12 GBG71281.1 - 0.063 13.4 4.1 0.12 12.4 4.1 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Nup160 PF11715.8 GBG71281.1 - 0.089 11.4 0.0 3.5 6.2 0.0 3.0 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Not3 PF04065.15 GBG71281.1 - 0.091 12.2 4.2 0.16 11.4 4.2 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF4559 PF15112.6 GBG71281.1 - 0.17 11.6 4.4 0.26 10.9 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) ADIP PF11559.8 GBG71281.1 - 0.21 11.7 5.8 0.15 12.1 4.1 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 GBG71281.1 - 0.54 10.8 7.5 1.1 9.8 7.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Cep57_CLD PF14073.6 GBG71281.1 - 0.94 9.5 10.6 1.8 8.6 10.6 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 WD40 PF00400.32 GBG71282.1 - 3.8e-16 59.2 2.3 0.00013 22.7 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 GBG71282.1 - 7.1e-12 45.2 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG71282.1 - 8.5e-11 41.7 0.5 1.7e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain ANAPC4_WD40 PF12894.7 GBG71282.1 - 0.026 14.8 0.1 5.2 7.4 0.0 3.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Macoilin PF09726.9 GBG71282.1 - 0.18 10.3 18.4 0.24 9.9 18.4 1.1 1 0 0 1 1 1 0 Macoilin family ARGLU PF15346.6 GBG71282.1 - 0.42 10.5 26.0 0.88 9.4 26.0 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 AAA_11 PF13086.6 GBG71282.1 - 0.8 9.4 9.7 1.2 8.8 9.7 1.4 1 0 0 1 1 1 0 AAA domain DDHD PF02862.17 GBG71282.1 - 1.1 9.3 4.1 1.7 8.7 4.1 1.3 1 0 0 1 1 1 0 DDHD domain Exonuc_VII_L PF02601.15 GBG71282.1 - 3.9 7.0 8.7 6 6.3 8.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP11 PF06644.11 GBG71282.1 - 4.3 7.0 9.9 6.6 6.4 9.9 1.3 1 0 0 1 1 1 0 ATP11 protein DUF659 PF04937.15 GBG71284.1 - 3.2e-30 105.0 0.0 7.3e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71284.1 - 0.00061 19.5 0.2 0.0016 18.2 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Astro_capsid_p PF12226.8 GBG71285.1 - 0.91 8.6 11.0 1.4 8.0 11.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2457 PF10446.9 GBG71285.1 - 1.3 8.1 12.5 1.8 7.6 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 GBG71285.1 - 4.8 5.4 8.1 5.8 5.1 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP70 PF00012.20 GBG71286.1 - 9.5e-260 862.9 4.2 1.1e-259 862.7 4.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG71286.1 - 7.5e-15 54.6 0.4 9.9e-14 50.9 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG71286.1 - 0.021 14.5 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain PG_binding_4 PF12229.8 GBG71286.1 - 0.031 14.5 3.8 0.083 13.2 3.8 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DDR PF08841.10 GBG71286.1 - 0.044 12.8 0.1 0.76 8.7 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 GBG71286.1 - 0.11 11.8 0.7 0.44 9.8 0.2 2.2 1 1 0 2 2 2 0 Hydantoinase/oxoprolinase DUF4795 PF16043.5 GBG71286.1 - 1.4 8.5 9.7 5.2 6.6 9.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF659 PF04937.15 GBG71287.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG71288.1 - 5.5e-13 49.0 0.0 8.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG71290.1 - 1.6e-12 47.5 0.0 2.7e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71290.1 - 0.027 14.2 0.1 0.056 13.2 0.1 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region zf-CCHC PF00098.23 GBG71292.1 - 5.8e-06 26.2 2.9 5.8e-06 26.2 2.9 1.7 2 0 0 2 2 2 1 Zinc knuckle CAF-1_p150 PF11600.8 GBG71292.1 - 0.064 13.0 16.7 0.097 12.4 16.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SSURE PF11966.8 GBG71292.1 - 0.089 12.6 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Fibronectin-binding repeat zf-CCHC_6 PF15288.6 GBG71292.1 - 0.11 12.3 0.3 0.28 11.0 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle TLP-20 PF06088.11 GBG71292.1 - 0.15 11.9 2.8 0.22 11.4 2.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HNOBA PF07701.14 GBG71292.1 - 0.22 10.9 1.5 0.3 10.5 1.5 1.1 1 0 0 1 1 1 0 Heme NO binding associated RRN3 PF05327.11 GBG71292.1 - 0.35 9.3 5.0 0.47 8.9 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-CCHC_4 PF14392.6 GBG71292.1 - 0.38 10.5 1.7 0.76 9.6 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Eapp_C PF10238.9 GBG71292.1 - 0.49 10.5 4.0 0.74 9.9 4.0 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein HCMV_UL139 PF12507.8 GBG71292.1 - 3.2 8.1 10.4 5.9 7.3 6.7 2.1 1 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein TcdA_TcdB PF12919.7 GBG71296.1 - 0.21 10.9 0.1 0.45 9.7 0.0 1.5 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain RT_RNaseH_2 PF17919.1 GBG71298.1 - 6.8e-29 99.8 0.0 1.3e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71298.1 - 9.2e-27 93.4 0.0 1.9e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71298.1 - 2e-17 63.4 0.0 3.6e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG71298.1 - 0.00035 20.4 0.1 0.00082 19.2 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71298.1 - 0.0011 19.4 0.0 0.0031 18.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG71298.1 - 0.0038 17.2 0.4 0.01 15.9 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG71298.1 - 0.0068 17.0 0.0 0.02 15.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71298.1 - 0.041 13.7 0.1 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Nop14 PF04147.12 GBG71298.1 - 0.38 8.9 36.3 0.61 8.2 36.3 1.2 1 0 0 1 1 1 0 Nop14-like family MDM1 PF15501.6 GBG71298.1 - 0.89 8.6 26.3 1.6 7.8 26.3 1.3 1 0 0 1 1 1 0 Nuclear protein MDM1 MULE PF10551.9 GBG71299.1 - 6e-17 61.9 0.0 1.1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG71299.1 - 6.7e-09 35.6 0.1 1.6e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 MuDR family transposase SWIM PF04434.17 GBG71299.1 - 0.01 15.5 0.6 0.022 14.4 0.6 1.5 1 0 0 1 1 1 0 SWIM zinc finger Transposase_mut PF00872.18 GBG71299.1 - 0.019 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family DUF659 PF04937.15 GBG71300.1 - 3.5e-05 23.7 0.0 5.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG71302.1 - 2.8e-15 56.4 0.3 6.1e-08 32.4 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG71302.1 - 3.8e-11 43.1 0.0 8.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) TSC22 PF01166.18 GBG71302.1 - 0.25 11.7 0.9 8.5 6.8 0.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family MULE PF10551.9 GBG71304.1 - 1.9e-16 60.3 0.1 3.4e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG71304.1 - 1.2e-06 28.4 0.3 3.3e-06 27.0 0.3 1.7 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.18 GBG71304.1 - 0.00085 18.3 0.1 0.0014 17.6 0.1 1.2 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 GBG71305.1 - 2.5e-17 63.1 0.1 6.7e-17 61.7 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG71305.1 - 8.7e-06 25.6 0.4 2.2e-05 24.3 0.4 1.6 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.18 GBG71305.1 - 2.1e-05 23.6 0.1 3.3e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Ribosomal_S17e PF00833.18 GBG71305.1 - 0.56 10.1 2.2 7 6.6 0.4 2.8 2 1 1 3 3 3 0 Ribosomal S17 Rrp15p PF07890.12 GBG71306.1 - 0.037 14.4 2.4 0.047 14.0 2.4 1.1 1 0 0 1 1 1 0 Rrp15p FAM176 PF14851.6 GBG71306.1 - 0.065 12.9 1.9 0.077 12.7 1.9 1.2 1 0 0 1 1 1 0 FAM176 family Ribosomal_60s PF00428.19 GBG71306.1 - 0.068 13.8 5.7 0.11 13.1 5.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.18 GBG71306.1 - 0.083 12.8 0.9 0.1 12.5 0.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.14 GBG71306.1 - 2 6.6 3.8 2.2 6.5 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG71307.1 - 0.86 7.7 15.5 1 7.5 15.5 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG71307.1 - 1.1 9.0 12.8 1.3 8.8 12.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RPN2_C PF18004.1 GBG71307.1 - 1.9 8.4 11.7 2.2 8.2 11.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pox_Ag35 PF03286.14 GBG71307.1 - 1.9 8.2 10.6 2.4 7.9 10.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 GBG71307.1 - 2.2 7.5 9.9 3 7.1 9.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3464 PF11947.8 GBG71308.1 - 2.3e-35 121.5 0.0 4.2e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 DDE_Tnp_4 PF13359.6 GBG71309.1 - 9.9e-32 109.8 0.1 6.2e-31 107.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71309.1 - 6.7e-17 61.8 0.0 1.2e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71309.1 - 0.0028 17.3 0.5 1.6 8.4 0.0 2.8 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG71309.1 - 0.069 13.5 0.5 0.82 10.1 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG71311.1 - 4.8e-08 33.3 0.7 7.6e-07 29.4 0.3 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG71312.1 - 0.19 11.9 1.4 0.37 11.0 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG71313.1 - 7.3e-32 109.4 0.0 1.5e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71313.1 - 1.7e-28 98.9 0.1 4.1e-28 97.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71313.1 - 1.8e-22 80.0 0.2 2.6e-11 43.5 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71313.1 - 9.9e-18 64.0 0.0 2e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71313.1 - 2.3e-10 40.7 0.0 4.8e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF3629 PF12302.8 GBG71313.1 - 5.3 6.4 9.9 11 5.4 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) tRNA_U5-meth_tr PF05958.11 GBG71314.1 - 8.5e-16 57.9 0.3 5.7e-08 32.1 0.0 2.5 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GBG71314.1 - 1.2e-09 38.1 0.1 2.5e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG71314.1 - 1.2e-07 32.3 0.3 4.3e-07 30.6 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG71314.1 - 7.4e-05 22.4 0.1 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 GBG71314.1 - 0.00028 20.5 0.0 0.0006 19.4 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 GBG71314.1 - 0.00085 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GBG71314.1 - 0.0015 18.0 0.1 0.0027 17.2 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 GBG71314.1 - 0.0021 18.7 0.1 0.0069 17.0 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GBG71314.1 - 0.0021 17.9 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 GBG71314.1 - 0.004 16.6 0.1 0.0077 15.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 GBG71314.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) AviRa PF11599.8 GBG71314.1 - 0.14 11.6 3.3 0.15 11.5 0.0 2.3 2 1 1 3 3 3 0 RRNA methyltransferase AviRa Dimer_Tnp_hAT PF05699.14 GBG71315.1 - 0.022 14.5 0.1 0.041 13.7 0.1 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region SLC12 PF03522.15 GBG71315.1 - 3.3 6.6 24.1 6.2 5.7 24.1 1.6 1 0 0 1 1 1 0 Solute carrier family 12 DUF659 PF04937.15 GBG71316.1 - 7.8e-19 68.0 0.0 1.4e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG71316.1 - 1.5e-15 57.0 0.1 5.5e-13 48.8 0.0 3.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG71316.1 - 4.8e-13 49.3 0.0 9e-12 45.2 0.0 2.9 2 1 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG71317.1 - 6.1e-31 106.4 0.0 7.6e-30 102.9 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71317.1 - 7.4e-30 103.3 0.1 8.5e-29 99.9 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71317.1 - 4.8e-26 91.6 0.1 9.6e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71317.1 - 1.8e-19 69.6 0.4 4.3e-19 68.4 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71317.1 - 2.2e-16 60.1 0.0 6.8e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71317.1 - 0.00097 19.3 0.1 0.003 17.7 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCCH PF00642.24 GBG71318.1 - 8.3e-07 28.8 5.3 1.3e-06 28.1 5.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GBG71318.1 - 0.093 13.4 0.7 0.093 13.4 0.7 2.0 2 0 0 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 GBG71318.1 - 0.2 11.8 6.7 0.36 11.0 6.7 1.4 1 0 0 1 1 1 0 Zinc finger domain RT_RNaseH_2 PF17919.1 GBG71319.1 - 2.4e-22 78.8 0.0 5.6e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71319.1 - 3.1e-21 75.6 0.0 8.1e-20 71.1 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG71319.1 - 0.00038 20.9 0.0 0.00087 19.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG71319.1 - 0.0034 17.2 0.2 0.024 14.5 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG71319.1 - 0.0059 17.2 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG71319.1 - 0.034 14.4 0.0 0.12 12.7 0.0 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein RVP PF00077.20 GBG71319.1 - 0.035 14.4 0.0 0.095 13.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease STT3 PF02516.14 GBG71322.1 - 4.3e-89 299.7 32.7 2e-84 284.3 27.8 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit RT_RNaseH PF17917.1 GBG71323.1 - 1.1e-23 83.4 0.0 3.3e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71323.1 - 8e-22 77.2 0.0 1.6e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71323.1 - 3.4e-19 68.7 1.4 8.7e-19 67.4 1.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71323.1 - 1e-14 54.7 0.0 4.2e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG71323.1 - 0.0044 17.2 0.2 0.0086 16.3 0.2 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Plavaka PF18759.1 GBG71324.1 - 1.4e-26 93.5 0.1 2.8e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Plavaka transposase TFIIA PF03153.13 GBG71324.1 - 0.88 9.5 13.9 2.1 8.3 12.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PIGA PF08288.12 GBG71325.1 - 5.4e-37 126.3 1.7 1.1e-36 125.3 0.3 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 GBG71325.1 - 1.5e-29 103.2 1.1 2.4e-29 102.5 1.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 GBG71325.1 - 4.7e-27 94.6 0.0 7.3e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG71325.1 - 3.4e-22 79.3 0.8 8.4e-22 78.0 0.4 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GBG71325.1 - 4.6e-13 49.9 0.4 1.1e-12 48.7 0.4 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GBG71325.1 - 0.0034 17.7 0.0 0.0081 16.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 GBG71325.1 - 0.018 15.1 0.1 0.036 14.1 0.1 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like gag-asp_proteas PF13975.6 GBG71326.1 - 1.3e-06 28.8 0.1 3.6e-06 27.4 0.1 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71326.1 - 0.00023 21.7 0.1 0.00054 20.6 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71326.1 - 0.00052 19.8 0.1 0.00079 19.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71326.1 - 0.0056 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease cNMP_binding PF00027.29 GBG71326.1 - 0.11 12.6 0.0 0.9 9.6 0.0 2.3 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain Retrotrans_gag PF03732.17 GBG71327.1 - 0.95 9.8 4.4 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein DUF4407 PF14362.6 GBG71327.1 - 9.7 5.4 18.1 9.6 5.5 16.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GTP_EFTU PF00009.27 GBG71328.1 - 1.5e-62 210.6 0.0 2.1e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GBG71328.1 - 1.3e-30 105.7 0.0 3.8e-30 104.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 GBG71328.1 - 1.8e-21 76.0 0.0 4.8e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GBG71328.1 - 8.5e-13 48.2 0.0 1.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 GBG71328.1 - 1.8e-12 47.5 0.0 4.6e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG71328.1 - 0.0041 17.2 0.1 0.0089 16.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_25 PF13649.6 GBG71329.1 - 3.1e-06 27.8 0.0 5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG71329.1 - 1.7e-05 24.7 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG71329.1 - 1.9e-05 24.1 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GBG71329.1 - 0.0042 16.9 0.0 0.0059 16.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GBG71329.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 GBG71329.1 - 0.039 14.7 0.0 0.06 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Nucleotid_trans PF03407.16 GBG71330.1 - 7.1e-32 111.1 0.0 6.2e-30 104.8 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-diphospho-sugar transferase rve PF00665.26 GBG71332.1 - 0.0062 16.7 0.1 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain PAN_4 PF14295.6 GBG71333.1 - 9.3e-05 22.3 2.6 0.00018 21.3 2.6 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 GBG71334.1 - 4.6e-05 23.2 2.9 6.9e-05 22.7 2.9 1.4 1 0 0 1 1 1 1 PAN domain DDE_Tnp_4 PF13359.6 GBG71339.1 - 5.1e-14 52.2 0.8 1.1e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71339.1 - 2.5e-07 30.5 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein PAN_4 PF14295.6 GBG71340.1 - 0.086 12.8 3.0 0.18 11.7 3.0 1.6 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.6 GBG71341.1 - 0.039 13.8 3.0 0.066 13.1 3.0 1.4 1 0 0 1 1 1 0 PAN domain DUF659 PF04937.15 GBG71342.1 - 1.6e-07 31.3 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71342.1 - 0.00063 19.5 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MPP6 PF10175.9 GBG71344.1 - 0.00051 20.6 0.2 0.00084 19.8 0.2 1.5 1 1 0 1 1 1 1 M-phase phosphoprotein 6 FoP_duplication PF13865.6 GBG71344.1 - 7.8 7.1 25.7 1 9.9 19.1 2.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 VID27_N PF17748.1 GBG71345.1 - 0.013 15.4 3.9 0.013 15.4 3.9 2.7 2 1 0 2 2 2 0 VID27 N-terminal region CDC45 PF02724.14 GBG71345.1 - 0.85 7.8 56.5 0.17 10.2 3.3 2.0 2 0 0 2 2 2 0 CDC45-like protein TPR_12 PF13424.6 GBG71346.1 - 8.3e-11 42.0 22.4 3.8e-05 23.9 0.2 6.4 5 3 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG71346.1 - 9.8e-06 25.2 12.1 0.12 11.7 3.6 3.4 1 1 2 3 3 3 3 MalT-like TPR region TPR_7 PF13176.6 GBG71346.1 - 0.0081 16.1 7.6 9.7 6.5 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG71346.1 - 0.088 13.0 20.2 1.8 8.9 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG71346.1 - 0.19 11.6 3.6 34 4.5 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG71346.1 - 0.21 11.9 4.5 3.2 8.2 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG71346.1 - 0.24 11.3 12.2 1.8 8.5 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG71346.1 - 1.8 9.6 28.1 6.6 7.8 2.2 7.5 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG71346.1 - 2.2 8.9 17.7 0.76 10.3 4.2 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat WW PF00397.26 GBG71347.1 - 9.2e-23 80.0 13.4 4.3e-11 42.7 2.2 2.5 2 0 0 2 2 2 2 WW domain ALMT PF11744.8 GBG71347.1 - 6.3 5.5 4.4 11 4.8 4.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter WW PF00397.26 GBG71348.1 - 9.1e-23 80.0 13.4 4.3e-11 42.7 2.2 2.5 2 0 0 2 2 2 2 WW domain ALMT PF11744.8 GBG71348.1 - 7.4 5.3 4.7 12 4.5 4.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DEAD PF00270.29 GBG71350.1 - 1.6e-21 76.8 0.0 2.5e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG71350.1 - 4e-08 33.6 0.0 9.4e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Spt5_N PF11942.8 GBG71350.1 - 3 8.9 33.5 3.9 8.5 0.9 4.6 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal HLH PF00010.26 GBG71351.1 - 1e-12 47.8 0.5 2e-12 46.8 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nop14 PF04147.12 GBG71353.1 - 5.6 5.1 7.9 11 4.1 7.9 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG71354.1 - 0.14 10.4 10.7 0.19 10.0 10.7 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG71354.1 - 0.32 10.4 13.7 0.49 9.8 13.7 1.3 1 0 0 1 1 1 0 SDA1 SMN PF06003.12 GBG71354.1 - 0.38 10.0 4.5 0.7 9.1 4.5 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Nop14 PF04147.12 GBG71354.1 - 0.63 8.2 13.2 0.78 7.9 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.9 GBG71354.1 - 0.9 9.6 16.4 1.7 8.7 16.4 1.6 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 GBG71354.1 - 1.3 8.6 9.1 2.8 7.6 9.1 1.5 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 GBG71354.1 - 1.6 7.4 4.5 2 7.1 4.5 1.2 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 GBG71354.1 - 2.6 7.3 21.0 3.8 6.8 21.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hid1 PF12722.7 GBG71354.1 - 3 5.9 4.3 3.4 5.7 4.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NOA36 PF06524.12 GBG71354.1 - 3.9 6.7 7.4 6.1 6.1 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein Roughex PF06020.11 GBG71354.1 - 5.4 6.0 12.4 9.3 5.2 12.4 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Merozoite_SPAM PF07133.11 GBG71354.1 - 6.4 6.7 21.9 12 5.9 21.9 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SspB PF04386.13 GBG71355.1 - 2.3 8.1 4.0 3.5 7.5 4.0 1.2 1 0 0 1 1 1 0 Stringent starvation protein B RVT_1 PF00078.27 GBG71358.1 - 2.6e-30 105.6 1.6 5.8e-30 104.5 0.0 2.3 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71358.1 - 1.1e-22 80.2 0.0 2.7e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71358.1 - 4.6e-22 77.9 0.0 1.2e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71358.1 - 6.1e-18 64.7 0.1 1.3e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG71358.1 - 1.2e-07 31.5 0.0 3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71358.1 - 3.4e-07 30.8 0.0 1.3e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71358.1 - 2.4e-05 24.8 0.0 0.00013 22.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG71358.1 - 0.017 15.4 0.8 0.15 12.4 0.1 3.0 2 0 0 2 2 2 0 Retrotransposon gag protein Ribosomal_60s PF00428.19 GBG71358.1 - 1.3 9.7 26.3 0.034 14.7 6.2 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF4187 PF13821.6 GBG71358.1 - 2.3 8.0 6.9 0.27 11.1 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Na_trans_assoc PF06512.13 GBG71360.1 - 0.22 11.8 12.3 0.32 11.3 12.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG71360.1 - 8.7 4.4 27.5 12 4.0 27.5 1.1 1 0 0 1 1 1 0 Nop14-like family HEAT PF02985.22 GBG71361.1 - 1.4e-09 37.4 0.9 0.083 13.2 0.0 4.5 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 GBG71361.1 - 1.6e-06 28.4 1.8 0.0002 21.7 0.1 3.3 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 GBG71361.1 - 0.048 13.7 0.7 1.6 8.8 0.0 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RT_RNaseH PF17917.1 GBG71362.1 - 2.3e-30 105.0 0.2 1.9e-29 102.0 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71362.1 - 1.4e-29 102.0 0.0 8.3e-29 99.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71362.1 - 2.8e-18 65.8 1.6 6.6e-18 64.6 1.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71362.1 - 1.3e-13 51.1 0.0 3.6e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71362.1 - 0.013 15.7 0.3 0.036 14.3 0.3 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG71362.1 - 0.2 11.3 0.0 0.2 11.3 0.0 3.4 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase BST2 PF16716.5 GBG71364.1 - 0.014 15.9 14.9 0.014 15.9 14.9 13.2 2 2 12 14 14 14 0 Bone marrow stromal antigen 2 Lipase_GDSL PF00657.22 GBG71364.1 - 0.48 10.4 3.8 0.75 9.7 0.8 2.9 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase Coilin_N PF15862.5 GBG71365.1 - 0.15 11.8 14.0 0.26 11.1 14.0 1.4 1 1 0 1 1 1 0 Coilin N-terminus Paf1 PF03985.13 GBG71365.1 - 1.7 7.5 21.4 1.9 7.4 21.4 1.0 1 0 0 1 1 1 0 Paf1 DUF4820 PF16091.5 GBG71365.1 - 2 7.7 17.1 2.5 7.4 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 GBG71365.1 - 2.3 8.0 21.1 2.5 7.9 21.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 GBG71365.1 - 3.1 7.9 12.4 3.8 7.6 12.4 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 GBG71365.1 - 5.2 5.7 20.3 5.4 5.7 20.3 1.0 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 GBG71365.1 - 5.9 5.8 11.7 6.7 5.6 11.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RP-C_C PF11800.8 GBG71365.1 - 6.1 6.9 15.5 7.5 6.6 15.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region tRNA_bind_2 PF13725.6 GBG71365.1 - 6.4 6.4 12.7 6.7 6.3 12.7 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain EOS1 PF12326.8 GBG71365.1 - 6.5 6.6 9.4 7.8 6.4 9.4 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF4746 PF15928.5 GBG71365.1 - 7.8 5.8 16.1 9.3 5.6 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 GBG71365.1 - 8.6 4.5 20.3 9.1 4.4 20.3 1.0 1 0 0 1 1 1 0 CDC45-like protein C2 PF00168.30 GBG71366.1 - 1.9e-29 102.0 0.2 2.3e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 GBG71366.1 - 0.0085 15.6 0.0 0.024 14.1 0.0 1.8 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain FMN_red PF03358.15 GBG71367.1 - 1.9e-14 53.7 0.0 2.6e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GBG71367.1 - 4.7e-08 33.0 0.0 5.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 GBG71367.1 - 0.00014 22.1 0.1 0.0014 18.8 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.15 GBG71368.1 - 9.8e-13 48.1 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GBG71368.1 - 6.7e-07 29.2 0.0 8.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 GBG71368.1 - 6e-05 23.3 0.1 0.00019 21.6 0.1 1.8 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 GBG71368.1 - 0.073 13.3 0.0 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain zf-CCHC PF00098.23 GBG71369.1 - 0.00014 21.8 2.4 0.00038 20.4 2.4 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG71369.1 - 0.02 14.7 0.1 0.08 12.8 0.1 2.1 1 0 0 1 1 1 0 Zinc knuckle Spore_III_AF PF09581.10 GBG71369.1 - 0.092 12.8 8.0 0.13 12.3 8.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) zf-C2H2_10 PF16588.5 GBG71369.1 - 0.11 12.2 2.3 0.26 11.1 2.3 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger AAA_23 PF13476.6 GBG71369.1 - 0.14 12.7 6.5 0.2 12.2 6.5 1.3 1 0 0 1 1 1 0 AAA domain DUF572 PF04502.13 GBG71369.1 - 0.28 10.8 14.5 0.41 10.2 14.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hydin_ADK PF17213.3 GBG71369.1 - 0.43 10.8 6.4 0.76 10.0 6.4 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MCM3AP_GANP PF16769.5 GBG71369.1 - 1.1 7.4 8.3 1.5 7.0 8.3 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP DUF1676 PF07898.13 GBG71369.1 - 3.9 7.5 7.5 7 6.6 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Presenilin PF01080.17 GBG71369.1 - 7.9 5.1 5.1 8.3 5.1 5.1 1.2 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG71370.1 - 6.9e-14 51.9 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 GBG71370.1 - 0.0042 16.9 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG71372.1 - 0.00035 20.9 2.1 0.0007 19.9 2.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF1970 PF09301.10 GBG71372.1 - 0.19 12.0 2.8 0.51 10.6 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1970) zf-CCHC PF00098.23 GBG71373.1 - 1.2e-06 28.3 3.6 3e-06 27.1 3.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG71373.1 - 0.1 12.3 1.9 0.23 11.2 1.9 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG71373.1 - 0.14 12.0 1.0 0.43 10.3 1.0 1.8 1 0 0 1 1 1 0 Zinc knuckle FHIPEP PF00771.20 GBG71373.1 - 0.16 10.4 2.5 0.26 9.7 2.5 1.2 1 0 0 1 1 1 0 FHIPEP family Phage_Gp23 PF10669.9 GBG71373.1 - 7.9 6.8 12.1 15 5.9 9.7 2.8 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) Myb_DNA-bind_4 PF13837.6 GBG71374.1 - 1.6e-05 25.2 0.3 3.1e-05 24.3 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG71374.1 - 0.00038 20.6 0.2 0.00085 19.5 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG71374.1 - 0.037 14.3 0.2 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG71374.1 - 0.06 13.4 0.3 0.11 12.5 0.3 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain FAD_binding_8 PF08022.12 GBG71375.1 - 1.9e-17 63.3 0.0 4.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 GBG71375.1 - 6e-08 32.9 9.8 6e-08 32.9 9.8 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GBG71375.1 - 7.6e-07 29.4 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 GBG71375.1 - 0.033 14.6 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain RVT_1 PF00078.27 GBG71376.1 - 7.5e-30 104.1 0.0 1.2e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71376.1 - 1.9e-15 56.7 0.0 4.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71376.1 - 3.5e-14 53.0 0.0 7.4e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain CLP1_P PF16575.5 GBG71377.1 - 3.5e-36 124.8 0.0 6e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RT_RNaseH_2 PF17919.1 GBG71377.1 - 5.6e-25 87.3 0.0 1.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71377.1 - 5e-24 84.6 0.0 1.1e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG71377.1 - 5.5e-07 30.1 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71377.1 - 3.1e-06 27.6 0.0 6.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG71377.1 - 0.0019 18.0 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71377.1 - 0.0028 17.5 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease AAA_22 PF13401.6 GBG71377.1 - 0.017 15.4 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG71377.1 - 0.024 15.2 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GBG71377.1 - 0.04 14.4 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 GBG71377.1 - 0.043 14.3 0.0 0.078 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Retrotrans_gag PF03732.17 GBG71377.1 - 0.071 13.4 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Antifungal_prot PF11402.8 GBG71377.1 - 0.074 13.3 0.3 0.22 11.8 0.3 1.7 1 0 0 1 1 1 0 Antifungal protein AAA_21 PF13304.6 GBG71377.1 - 0.19 11.5 0.1 0.39 10.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Trns_repr_metal PF02583.17 GBG71378.1 - 0.034 14.5 0.1 0.058 13.8 0.1 1.3 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Methyltr_RsmB-F PF01189.17 GBG71379.1 - 1.1e-69 234.1 0.0 2.1e-69 233.2 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 GBG71379.1 - 1.3e-09 38.4 0.0 4.2e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 GBG71379.1 - 0.015 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Coilin_N PF15862.5 GBG71380.1 - 0.33 10.8 15.4 0.49 10.2 15.4 1.4 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 GBG71380.1 - 1.3 7.8 2.6 1.1 8.0 2.6 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 GBG71380.1 - 1.6 8.5 5.3 1.4 8.6 5.3 1.2 1 0 0 1 1 1 0 Connexin MDM10 PF12519.8 GBG71381.1 - 7.7 5.3 6.3 12 4.6 6.3 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PEPcase PF00311.17 GBG71382.1 - 3.2e-285 948.3 0.0 3.8e-285 948.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 GBG71382.1 - 0.003 16.2 0.0 0.0047 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Arm PF00514.23 GBG71384.1 - 1.1e-07 31.6 4.2 0.38 10.8 0.0 5.8 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat PUL PF08324.11 GBG71384.1 - 0.00018 20.9 0.2 0.00032 20.0 0.2 1.5 1 1 0 1 1 1 1 PUL domain Thioredoxin_3 PF13192.6 GBG71385.1 - 0.1 12.7 0.1 8 6.6 0.2 2.5 2 0 0 2 2 2 0 Thioredoxin domain PRIMA1 PF16101.5 GBG71385.1 - 3.9 7.5 6.0 5.7 7.0 1.3 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PEPcase PF00311.17 GBG71386.1 - 1.2e-282 939.7 0.0 1.5e-282 939.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 GBG71386.1 - 0.00021 19.9 0.0 0.00039 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase CDC45 PF02724.14 GBG71390.1 - 0.1 10.9 14.6 0.15 10.3 14.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG71390.1 - 2.7 7.3 20.7 4.4 6.6 20.7 1.3 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 GBG71390.1 - 3.2 7.7 30.8 5 7.1 30.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DNA_pol_phi PF04931.13 GBG71390.1 - 4.7 5.2 23.6 6.3 4.8 23.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 GBG71390.1 - 4.8 5.8 8.6 7.1 5.3 8.6 1.2 1 0 0 1 1 1 0 Presenilin DDE_Tnp_4 PF13359.6 GBG71391.1 - 3.2e-27 95.1 0.0 5e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71391.1 - 1.1e-12 48.0 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71391.1 - 0.042 13.5 0.0 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG71392.1 - 3.4e-07 30.6 0.6 4.4e-06 27.0 0.3 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG71394.1 - 1.1e-10 41.4 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG71394.1 - 0.039 12.2 12.8 0.046 12.0 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG71394.1 - 1.4 8.3 16.3 1.6 8.1 16.3 1.1 1 0 0 1 1 1 0 SDA1 DUF4746 PF15928.5 GBG71394.1 - 3.9 6.8 10.7 4.7 6.5 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GRAM PF02893.20 GBG71398.1 - 2e-08 34.1 0.4 7.6e-07 29.0 0.3 2.8 3 0 0 3 3 3 1 GRAM domain Membr_traf_MHD PF10540.9 GBG71398.1 - 3.5e-06 27.3 0.1 0.0025 18.0 0.0 3.0 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 GBG71398.1 - 1.8e-05 23.5 0.4 4e-05 22.4 0.1 1.7 2 1 0 2 2 2 1 Plant family of unknown function (DUF810) PH_TFIIH PF08567.11 GBG71398.1 - 0.015 15.7 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain Suv3_N PF18114.1 GBG71398.1 - 0.022 14.9 0.0 32 4.7 0.0 3.5 3 0 0 3 3 3 0 Suv3 helical N-terminal domain DDE_Tnp_4 PF13359.6 GBG71400.1 - 1.7e-05 24.5 0.9 3.2e-05 23.6 0.4 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71400.1 - 0.011 15.4 0.2 0.016 14.8 0.2 1.2 1 0 0 1 1 1 0 Plant transposon protein YscK PF06578.12 GBG71400.1 - 0.11 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) SDA1 PF05285.12 GBG71401.1 - 0.0039 16.7 10.6 0.0039 16.7 10.6 1.1 1 0 0 1 1 1 1 SDA1 PPP4R2 PF09184.11 GBG71401.1 - 0.039 13.6 9.1 0.036 13.6 9.1 1.2 1 0 0 1 1 1 0 PPP4R2 CobT PF06213.12 GBG71401.1 - 0.49 9.7 15.3 0.68 9.3 15.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFB6 PF17110.5 GBG71401.1 - 0.76 9.5 9.5 1.1 9.0 9.5 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH BUD22 PF09073.10 GBG71401.1 - 1.3 8.3 11.9 1.3 8.2 11.9 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG71401.1 - 7 4.7 21.8 8 4.5 21.8 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 GBG71401.1 - 9.7 6.1 20.2 9.3 6.1 20.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2358 PF10184.9 GBG71402.1 - 1.2e-06 28.8 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) zf-CCHC PF00098.23 GBG71403.1 - 1.9e-05 24.5 4.0 3.2e-05 23.8 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG71403.1 - 0.59 10.0 3.1 1 9.2 3.1 1.3 1 0 0 1 1 1 0 Zinc knuckle BT1 PF03092.16 GBG71403.1 - 5 5.2 6.1 7.4 4.7 6.1 1.1 1 0 0 1 1 1 0 BT1 family RVT_connect PF06815.13 GBG71404.1 - 0.093 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase connection domain PTPRCAP PF15713.5 GBG71404.1 - 3.1 8.1 12.9 5.6 7.3 12.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RT_RNaseH_2 PF17919.1 GBG71405.1 - 1.9e-29 101.6 0.0 3.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71405.1 - 2e-26 92.3 0.0 3.2e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71405.1 - 6.3e-09 35.7 0.0 9.2e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NARP1 PF12569.8 GBG71405.1 - 1.6 7.5 9.5 2.6 6.8 9.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BUD22 PF09073.10 GBG71405.1 - 2.6 7.3 34.2 3.7 6.8 34.2 1.1 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 GBG71405.1 - 3.5 6.3 10.4 4.8 5.9 10.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 GBG71405.1 - 4.3 6.2 5.2 5.9 5.8 5.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 C6_DPF PF10170.9 GBG71406.1 - 0.15 12.4 0.5 0.52 10.7 0.2 1.9 2 0 0 2 2 2 0 Cysteine-rich domain RT_RNaseH_2 PF17919.1 GBG71407.1 - 2.5e-36 123.7 0.0 4e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71407.1 - 4.8e-28 97.5 0.0 8.3e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71407.1 - 7.3e-12 45.3 0.1 1e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2OG-FeII_Oxy_2 PF13532.6 GBG71408.1 - 6.1e-44 150.6 0.0 9.5e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2HC5 PF06221.13 GBG71408.1 - 2.7e-11 43.3 7.5 4.8e-11 42.5 7.5 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type RVT_1 PF00078.27 GBG71409.1 - 3.2e-29 102.0 0.0 5.3e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71409.1 - 6.9e-18 64.5 0.0 3.2e-15 56.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71409.1 - 4.6e-16 58.7 0.0 1.1e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71409.1 - 6.3e-12 45.7 0.0 1.8e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG71409.1 - 6.5e-08 32.8 0.0 6.9e-07 29.5 0.0 2.5 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG71409.1 - 2.8e-05 24.3 0.0 7.5e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG71411.1 - 5.3e-34 116.2 0.0 9.8e-34 115.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71411.1 - 5.6e-33 113.4 0.0 1e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71411.1 - 1.3e-18 67.4 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG71411.1 - 9.1e-06 25.5 0.3 1.9e-05 24.5 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG71411.1 - 0.00018 21.2 0.9 0.00044 20.0 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Putative_G5P PF17426.2 GBG71413.1 - 0.16 12.1 0.8 0.35 11.0 0.8 1.5 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P CNP_C_terminal PF17839.1 GBG71413.1 - 1.6 9.5 6.8 0.27 12.0 1.0 2.2 2 1 0 2 2 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase Exonuc_VII_L PF02601.15 GBG71413.1 - 2.6 7.5 9.5 3.3 7.2 9.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PK PF00224.21 GBG71414.1 - 2.4e-153 510.1 1.4 2.4e-153 510.1 1.4 1.3 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG71414.1 - 2.3e-20 73.0 0.6 6.5e-20 71.5 0.3 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GBG71414.1 - 0.016 14.4 0.4 0.056 12.6 0.1 1.8 1 1 1 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family DUF371 PF04027.13 GBG71414.1 - 0.066 13.2 0.2 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF371) Ciart PF15673.5 GBG71414.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor Cuticle_1 PF08140.11 GBG71414.1 - 0.23 11.5 0.9 0.61 10.2 0.0 2.2 3 0 0 3 3 3 0 Crustacean cuticle protein repeat Integrase_H2C2 PF17921.1 GBG71415.1 - 1e-15 57.6 0.1 4.2e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG71415.1 - 9.5e-11 41.4 0.0 2.6e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG71415.1 - 1.2e-09 38.4 0.0 4e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71415.1 - 4e-05 23.8 0.0 9.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Tropomyosin_1 PF12718.7 GBG71415.1 - 4.7 7.4 29.8 0.47 10.6 4.4 3.7 2 1 1 3 3 3 0 Tropomyosin like PRKG1_interact PF15898.5 GBG71415.1 - 5.4 8.0 34.3 1.8 9.5 0.9 4.9 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain DDE_Tnp_4 PF13359.6 GBG71416.1 - 4.4e-30 104.4 0.0 3.4e-29 101.6 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71416.1 - 6.3e-17 61.8 0.0 1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71416.1 - 0.00054 19.7 0.0 0.041 13.5 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain gag-asp_proteas PF13975.6 GBG71417.1 - 2.8e-07 31.0 0.0 1e-06 29.2 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71417.1 - 8.5e-05 23.1 0.1 0.00022 21.8 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71417.1 - 0.00023 21.0 0.7 0.0012 18.7 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG71417.1 - 0.0029 17.4 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-RING_11 PF17123.5 GBG71418.1 - 4.5e-12 45.5 17.7 5.8e-06 26.0 4.5 2.9 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_2 PF13639.6 GBG71418.1 - 2.4e-11 43.8 30.6 1.8e-07 31.4 10.2 3.6 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 GBG71418.1 - 1.9e-08 34.1 26.1 1.7e-06 27.9 10.3 3.2 3 0 0 3 3 3 2 zinc-RING finger domain zf-rbx1 PF12678.7 GBG71418.1 - 3.9e-08 33.5 22.9 9.2e-05 22.7 8.4 3.1 3 0 0 3 3 2 2 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GBG71418.1 - 1.7e-07 31.1 28.1 5.7e-06 26.3 7.5 3.4 4 0 0 4 4 3 2 RING-type zinc-finger RVT_1 PF00078.27 GBG71418.1 - 1.6e-06 27.8 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG71418.1 - 1.7e-06 28.5 0.0 8.9e-06 26.2 0.0 2.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-C3HC4 PF00097.25 GBG71418.1 - 1.4e-05 24.8 25.9 4.4e-05 23.3 10.9 2.9 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG71418.1 - 8.5e-05 22.3 26.7 0.00058 19.7 10.6 3.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GBG71418.1 - 0.00023 21.1 17.1 0.0045 17.0 3.9 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger IQ PF00612.27 GBG71418.1 - 0.00095 18.8 3.1 0.0038 16.9 3.1 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif Asp_protease_2 PF13650.6 GBG71418.1 - 0.0011 19.5 0.0 0.0037 17.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease zf-C3HC4_3 PF13920.6 GBG71418.1 - 0.0038 17.0 8.8 0.0038 17.0 8.8 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) RVP PF00077.20 GBG71418.1 - 0.034 14.5 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71418.1 - 0.075 12.8 0.9 0.15 11.9 0.9 1.4 1 0 0 1 1 1 0 Aspartyl protease Zn_ribbon_17 PF17120.5 GBG71418.1 - 0.15 11.7 15.6 1.2 8.9 1.3 2.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 GBG71418.1 - 0.17 11.7 12.2 1.2 9.0 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 GBG71418.1 - 2.4 8.1 14.9 8.9 6.3 0.5 3.0 2 0 0 2 2 2 0 PHD-finger Jnk-SapK_ap_N PF09744.9 GBG71418.1 - 3 8.0 17.3 0.017 15.3 2.6 3.6 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Zf_RING PF16744.5 GBG71418.1 - 4.8 7.4 11.5 10 6.3 5.8 2.9 2 0 0 2 2 2 0 KIAA1045 RING finger Prok-RING_4 PF14447.6 GBG71418.1 - 8.2 6.4 26.7 0.13 12.1 9.5 4.1 3 2 2 5 5 5 0 Prokaryotic RING finger family 4 gag-asp_proteas PF13975.6 GBG71420.1 - 5.4e-08 33.3 0.1 1.3e-07 32.1 0.1 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71420.1 - 5.6e-06 26.9 0.1 1.4e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71420.1 - 1.7e-05 24.6 0.1 2.5e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71420.1 - 0.0092 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Cation_ATPase PF13246.6 GBG71421.1 - 4.1e-09 36.4 0.0 8.9e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GBG71421.1 - 0.00013 22.4 0.0 0.00033 21.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SSB PF00436.25 GBG71421.1 - 0.0068 16.4 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 Single-strand binding protein family FHIPEP PF00771.20 GBG71421.1 - 0.023 13.2 0.0 0.038 12.5 0.0 1.2 1 0 0 1 1 1 0 FHIPEP family BUD22 PF09073.10 GBG71422.1 - 2.3 7.5 51.2 0.088 12.1 22.4 2.2 2 0 0 2 2 2 0 BUD22 VDE PF07137.11 GBG71423.1 - 7.8e-41 140.2 0.1 1.7e-40 139.1 0.0 1.6 2 0 0 2 2 2 1 VDE lipocalin domain DUF3479 PF11965.8 GBG71423.1 - 3.5e-06 27.2 0.1 8.1e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3479) GYD PF08734.11 GBG71423.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 GYD domain DUF4033 PF13225.6 GBG71424.1 - 2.9e-35 120.1 0.2 6.7e-35 118.9 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) RVT_1 PF00078.27 GBG71424.1 - 5.1e-23 81.7 0.0 1.1e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG71424.1 - 0.0009 19.4 0.1 0.0031 17.7 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG71424.1 - 0.0065 16.7 2.9 0.11 12.8 0.0 3.9 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG71424.1 - 0.0074 16.2 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Senescence_reg PF04520.13 GBG71424.1 - 8.8 7.1 9.7 0.43 11.4 2.3 2.5 2 0 0 2 2 2 0 Senescence regulator DUF4033 PF13225.6 GBG71425.1 - 1.7e-41 140.1 2.6 2.5e-24 85.1 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4033) RVT_1 PF00078.27 GBG71425.1 - 5.3e-23 81.7 0.0 1.1e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG71425.1 - 0.00094 19.4 0.1 0.0032 17.7 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG71425.1 - 0.0071 16.6 2.9 0.11 12.8 0.0 3.9 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG71425.1 - 0.0076 16.1 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Senescence_reg PF04520.13 GBG71425.1 - 9.3 7.1 9.7 0.44 11.4 2.3 2.5 2 0 0 2 2 2 0 Senescence regulator F-box PF00646.33 GBG71426.1 - 1.4e-05 24.8 0.0 1.4e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GBG71426.1 - 0.0023 17.8 0.1 0.0023 17.8 0.1 2.3 2 0 0 2 2 2 1 F-box-like SlyX PF04102.12 GBG71427.1 - 0.011 16.3 0.3 0.011 16.3 0.3 3.1 3 1 0 3 3 3 0 SlyX TRPM_tetra PF16519.5 GBG71427.1 - 0.069 13.3 1.9 0.53 10.4 0.0 2.8 2 1 1 3 3 3 0 Tetramerisation domain of TRPM TolA_bind_tri PF16331.5 GBG71427.1 - 2.2 8.4 10.0 0.88 9.7 4.0 2.7 1 1 1 2 2 2 0 TolA binding protein trimerisation PTS_IIA PF02255.16 GBG71427.1 - 9.6 6.3 9.4 1.8 8.6 2.4 2.9 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit DDE_Tnp_4 PF13359.6 GBG71429.1 - 6.6e-26 90.9 0.1 2e-25 89.3 0.0 1.9 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71429.1 - 5.9e-12 45.6 0.0 9.4e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71429.1 - 5e-05 23.0 0.4 0.00057 19.6 0.0 2.6 3 0 0 3 3 3 1 Transposase DDE domain Ion_trans PF00520.31 GBG71430.1 - 1.9e-20 73.2 12.1 2.5e-20 72.7 12.1 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 GBG71430.1 - 1.1e-06 28.6 0.0 8.8e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain IQ PF00612.27 GBG71430.1 - 0.02 14.6 3.1 0.062 13.1 3.1 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ribosomal_60s PF00428.19 GBG71430.1 - 0.048 14.2 3.6 0.18 12.4 4.1 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF624 PF04854.14 GBG71430.1 - 6.7 6.9 7.1 1.2 9.3 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF624 RVT_1 PF00078.27 GBG71431.1 - 3e-24 85.8 0.1 1e-23 84.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71431.1 - 7.8e-22 77.5 0.0 2.1e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71431.1 - 1.7e-21 76.1 0.0 5.2e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71431.1 - 3.7e-05 23.7 0.1 7.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG71431.1 - 0.0019 18.4 0.8 0.018 15.3 0.0 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG71432.1 - 3.4e-26 91.2 0.0 9.2e-26 89.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71432.1 - 8.6e-22 77.4 0.0 2.8e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase cNMP_binding PF00027.29 GBG71432.1 - 5e-06 26.5 0.0 0.00015 21.8 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 GBG71432.1 - 0.0029 16.9 0.4 0.12 11.5 0.1 2.3 2 0 0 2 2 2 1 Ion transport protein IQ PF00612.27 GBG71432.1 - 0.0044 16.7 3.0 0.019 14.7 3.0 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ribosomal_60s PF00428.19 GBG71432.1 - 0.08 13.5 15.0 0.25 11.9 14.7 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein AIP3 PF03915.13 GBG71432.1 - 0.082 12.0 3.3 0.16 11.1 0.1 2.5 2 0 0 2 2 2 0 Actin interacting protein 3 DDRGK PF09756.9 GBG71433.1 - 4.8e-53 179.5 17.9 6.6e-53 179.1 17.9 1.1 1 0 0 1 1 1 1 DDRGK domain FeoC PF09012.10 GBG71433.1 - 3.2e-05 23.9 0.2 0.033 14.3 0.1 2.5 2 0 0 2 2 2 2 FeoC like transcriptional regulator Borrelia_P83 PF05262.11 GBG71433.1 - 0.016 13.7 11.4 0.018 13.6 11.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RNA_polI_A34 PF08208.11 GBG71433.1 - 0.31 11.1 16.8 0.6 10.2 16.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 eIF3_subunit PF08597.10 GBG71433.1 - 0.38 10.6 23.2 0.55 10.1 23.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit XAP5 PF04921.14 GBG71433.1 - 0.43 10.3 10.7 0.63 9.8 10.7 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Atg14 PF10186.9 GBG71433.1 - 0.67 9.0 8.4 0.92 8.5 8.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GHMP_kinases_N PF00288.26 GBG71433.1 - 1.2 9.4 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain NAM-associated PF14303.6 GBG71433.1 - 1.8 9.3 18.0 2.9 8.6 18.0 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Nop53 PF07767.11 GBG71433.1 - 3.2 7.0 25.4 4.4 6.6 25.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 GBG71433.1 - 5 6.9 10.3 7.9 6.2 10.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG71433.1 - 5.2 5.7 9.0 6.8 5.4 9.0 1.3 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 GBG71433.1 - 6.4 6.0 14.8 11 5.3 14.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Integrase_H2C2 PF17921.1 GBG71434.1 - 7.9e-13 48.3 0.3 1.7e-12 47.3 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71434.1 - 2.6e-06 27.6 0.0 7.1e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG71434.1 - 8.6e-06 26.2 0.1 7.2e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71434.1 - 0.0021 18.7 0.0 0.0073 16.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG71434.1 - 0.017 15.4 0.2 1.3 9.4 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG71434.1 - 0.092 12.5 0.7 0.17 11.7 0.7 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG71434.1 - 0.17 12.2 0.0 0.47 10.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF659 PF04937.15 GBG71435.1 - 1.1e-09 38.4 0.2 2.7e-09 37.1 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71435.1 - 0.0034 17.1 0.0 0.0092 15.7 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Secretin_N_2 PF07655.13 GBG71435.1 - 4.4 7.9 9.1 63 4.2 7.1 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Myb_DNA-bind_4 PF13837.6 GBG71436.1 - 8.7e-08 32.4 2.7 1.9e-07 31.3 2.7 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG71436.1 - 0.0027 18.0 1.0 0.0075 16.6 1.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG71436.1 - 0.019 15.0 0.9 0.041 14.0 0.9 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG71436.1 - 0.51 10.6 6.5 0.058 13.6 0.6 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain ProRS-C_1 PF09180.11 GBG71437.1 - 4.9e-29 100.3 0.5 1.2e-28 99.1 0.5 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 GBG71437.1 - 8.3e-19 68.2 0.0 1.3e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GBG71437.1 - 1.2e-15 57.4 0.0 2.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain YebG PF07130.12 GBG71437.1 - 0.14 12.0 0.9 1.4 8.8 0.3 2.4 2 0 0 2 2 2 0 YebG protein DDE_Tnp_4 PF13359.6 GBG71438.1 - 5.1e-28 97.7 0.0 7.1e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71438.1 - 2.6e-17 63.1 0.0 4.1e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71438.1 - 0.033 13.8 0.7 5.8 6.5 0.0 2.5 2 1 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG71439.1 - 2.9e-08 34.0 2.5 5e-08 33.2 2.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain tRNA-synt_1f PF01921.18 GBG71439.1 - 0.0056 15.6 0.4 0.0077 15.2 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) RVT_1 PF00078.27 GBG71440.1 - 8.5e-10 38.5 0.1 2.2e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG71440.1 - 2.9e-07 30.3 0.0 7.9e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71440.1 - 1.2e-06 29.1 0.0 3.8e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71440.1 - 1.9e-05 25.1 0.0 8.6e-05 23.0 0.0 2.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TAF4 PF05236.14 GBG71440.1 - 0.0053 16.5 5.3 0.016 15.0 5.3 1.8 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Asp_protease PF09668.10 GBG71440.1 - 0.026 14.3 0.0 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG71440.1 - 0.027 14.7 6.9 0.05 13.9 0.1 3.9 4 0 0 4 4 4 0 Retrotransposon gag protein FAM76 PF16046.5 GBG71440.1 - 0.69 9.2 15.8 1.9 7.7 9.8 2.4 2 0 0 2 2 2 0 FAM76 protein Baculo_PEP_C PF04513.12 GBG71440.1 - 3.9 7.5 13.9 2.5 8.1 0.7 3.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pectinesterase PF01095.19 GBG71442.1 - 2.9e-84 282.3 1.2 3.9e-84 281.9 1.2 1.2 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.15 GBG71442.1 - 2.1e-06 28.1 1.7 5.1e-06 26.9 1.7 1.7 1 1 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor V-set PF07686.17 GBG71442.1 - 0.034 14.3 0.1 0.087 13.0 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin V-set domain RT_RNaseH_2 PF17919.1 GBG71443.1 - 4.5e-25 87.6 0.0 7.7e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71443.1 - 2.1e-24 85.8 0.0 3.7e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71443.1 - 1.7e-10 40.8 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG71443.1 - 0.3 10.5 22.0 0.41 10.0 22.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG71443.1 - 3.9 5.6 24.9 15 3.7 25.7 1.4 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 GBG71443.1 - 4.9 5.3 18.1 7 4.8 18.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG71445.1 - 6.1e-24 84.8 0.0 1.3e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71445.1 - 5.6e-23 80.9 0.0 1.2e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71445.1 - 8.7e-21 74.2 0.0 9.6e-20 70.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71445.1 - 3.5e-16 59.1 2.2 5e-16 58.5 0.3 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG71445.1 - 0.0029 17.8 0.1 0.0091 16.2 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG71445.1 - 0.0042 17.0 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG71445.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG71445.1 - 0.044 14.0 0.2 0.17 12.2 0.2 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein rve PF00665.26 GBG71445.1 - 0.068 13.4 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain DUF659 PF04937.15 GBG71446.1 - 3.6e-22 78.9 0.1 7.3e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG71446.1 - 1e-09 38.6 0.1 1.1e-07 32.1 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain DUF659 PF04937.15 GBG71447.1 - 2.3e-22 79.5 0.1 4.7e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71447.1 - 0.11 12.3 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region HECT_2 PF09814.9 GBG71448.1 - 8.8e-18 64.3 1.5 4e-09 35.8 0.4 2.1 2 0 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Cytochrom_CIII PF02085.16 GBG71448.1 - 0.45 10.9 10.8 0.13 12.7 2.0 2.8 3 0 0 3 3 3 0 Class III cytochrome C family RVT_1 PF00078.27 GBG71449.1 - 6.7e-28 97.7 0.0 1.1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71449.1 - 4.7e-27 93.9 0.0 3.7e-14 52.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71449.1 - 5.4e-25 87.7 0.0 1.4e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71449.1 - 5.1e-16 58.5 0.0 1.1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71449.1 - 8.9e-12 45.3 0.0 3.1e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71449.1 - 2.5e-05 24.4 0.0 6.5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Ribosomal_60s PF00428.19 GBG71449.1 - 0.14 12.8 2.7 0.3 11.7 2.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Cupin_1 PF00190.22 GBG71451.1 - 7e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 GBG71451.1 - 2.9e-05 23.7 0.7 5e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Cupin domain DUF1971 PF09313.11 GBG71451.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) RT_RNaseH_2 PF17919.1 GBG71453.1 - 3.1e-27 94.5 0.0 6.7e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71453.1 - 7.1e-25 87.3 0.0 1.4e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71453.1 - 1.3e-07 31.4 0.0 2.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG71453.1 - 0.0015 18.5 2.2 0.0032 17.5 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Nexin_C PF08628.12 GBG71453.1 - 0.068 13.8 1.4 0.2 12.2 1.4 1.8 1 0 0 1 1 1 0 Sorting nexin C terminal zf-CCHC_4 PF14392.6 GBG71453.1 - 0.63 9.8 2.1 1.2 8.9 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1943 PF09172.11 GBG71453.1 - 1.3 8.2 8.8 2.6 7.2 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) MDM10 PF12519.8 GBG71453.1 - 3.1 6.6 6.5 6.8 5.4 6.5 1.5 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FHIPEP PF00771.20 GBG71453.1 - 3.2 6.1 6.3 6.4 5.1 6.3 1.4 1 0 0 1 1 1 0 FHIPEP family TBCC_N PF16752.5 GBG71453.1 - 5.6 7.4 16.3 0.28 11.6 8.0 2.7 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Pkinase PF00069.25 GBG71454.1 - 2.7e-24 85.9 0.0 3.5e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71454.1 - 1.1e-12 47.8 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG71454.1 - 8.4e-09 34.7 0.0 1.1e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG71454.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GBG71454.1 - 0.18 10.7 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sugar_tr PF00083.24 GBG71455.1 - 1.9e-75 254.4 9.7 3.7e-53 181.0 2.2 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 GBG71455.1 - 1.9e-14 53.4 39.2 1.1e-13 50.9 19.9 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GBG71455.1 - 0.035 12.5 3.2 0.052 12.0 3.2 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) RVT_1 PF00078.27 GBG71456.1 - 1.7e-08 34.3 0.0 2.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RWP-RK PF02042.15 GBG71457.1 - 5.9e-22 77.4 0.1 1.1e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 GBG71457.1 - 0.0094 15.9 0.0 0.022 14.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family CENP-B_dimeris PF09026.10 GBG71458.1 - 0.0029 17.9 17.5 0.0029 17.9 17.5 3.7 2 1 0 2 2 2 1 Centromere protein B dimerisation domain DUF5313 PF17240.2 GBG71458.1 - 0.89 10.0 12.7 1.4 9.4 12.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5313) RVP_2 PF08284.11 GBG71459.1 - 3e-08 33.5 0.0 1.1e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71459.1 - 2.2e-06 28.2 0.0 5.5e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71459.1 - 3.7e-06 27.4 0.0 8.8e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG71459.1 - 0.0034 17.2 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Tudor-knot PF11717.8 GBG71459.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain RT_RNaseH_2 PF17919.1 GBG71460.1 - 2.8e-27 94.7 0.0 5.3e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71460.1 - 3.4e-24 85.1 0.0 6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2249 PF10006.9 GBG71460.1 - 0.025 14.5 0.1 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) zf-TAZ PF02135.16 GBG71461.1 - 7.6e-11 42.3 11.9 1.3e-10 41.6 10.0 2.4 2 0 0 2 2 2 1 TAZ zinc finger KIX_2 PF16987.5 GBG71461.1 - 0.032 14.2 0.2 0.056 13.5 0.2 1.4 1 0 0 1 1 1 0 KIX domain DUF957 PF06117.11 GBG71461.1 - 0.21 11.1 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) EF-hand_6 PF13405.6 GBG71462.1 - 4.8e-06 26.1 0.7 2.4e-05 23.9 0.1 2.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 GBG71462.1 - 1.7e-05 24.0 0.3 0.00013 21.3 0.1 2.4 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 GBG71462.1 - 2.1e-05 24.9 0.0 4.1e-05 24.0 0.0 1.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 GBG71462.1 - 0.0013 18.1 0.3 0.0031 16.9 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 GBG71462.1 - 0.064 13.1 0.2 0.29 11.0 0.0 2.2 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 GBG71463.1 - 4.2e-06 26.2 0.7 2.2e-05 24.0 0.1 2.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 GBG71463.1 - 1.5e-05 24.2 0.3 0.00012 21.4 0.1 2.4 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 GBG71463.1 - 1.9e-05 25.1 0.0 3.7e-05 24.1 0.0 1.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 GBG71463.1 - 0.0012 18.2 0.3 0.0029 17.0 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 GBG71463.1 - 0.056 13.3 0.2 0.27 11.1 0.0 2.2 2 1 1 3 3 3 0 EF-hand domain pair Nop14 PF04147.12 GBG71464.1 - 0.017 13.4 51.7 0.02 13.1 51.7 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG71464.1 - 0.44 9.3 27.3 0.53 9.0 27.3 1.3 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GBG71464.1 - 1.4 8.2 51.3 1.7 7.9 51.3 1.1 1 0 0 1 1 1 0 BUD22 DUF4045 PF13254.6 GBG71464.1 - 3.7 7.1 25.6 4.8 6.7 25.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) EF-hand_5 PF13202.6 GBG71465.1 - 2.5e-05 23.6 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 GBG71465.1 - 5.7e-05 22.4 0.0 0.0016 17.8 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GBG71465.1 - 0.00016 21.3 0.0 0.00044 20.0 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 GBG71465.1 - 0.00024 21.5 0.0 0.00032 21.1 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GBG71465.1 - 0.065 13.1 0.0 2.3 8.1 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain pair RT_RNaseH PF17917.1 GBG71466.1 - 3.9e-21 75.3 0.0 1e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71466.1 - 3.4e-20 71.9 0.0 8.8e-20 70.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71466.1 - 4e-06 26.5 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MIT_C PF16565.5 GBG71466.1 - 0.081 12.9 0.3 0.27 11.2 0.3 1.9 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT zf-U11-48K PF05253.12 GBG71467.1 - 0.0047 16.8 6.3 0.0047 16.8 6.3 1.8 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Rad51 PF08423.11 GBG71468.1 - 8.1e-111 369.3 0.0 1.2e-110 368.8 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 GBG71468.1 - 7.2e-12 45.3 0.2 1.3e-11 44.5 0.2 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 GBG71468.1 - 1.6e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GBG71468.1 - 0.0012 18.2 0.1 0.003 16.9 0.1 1.7 1 0 0 1 1 1 1 KaiC RB_A PF01858.17 GBG71468.1 - 0.65 9.8 2.1 25 4.6 0.3 2.8 3 0 0 3 3 3 0 Retinoblastoma-associated protein A domain RT_RNaseH PF17917.1 GBG71470.1 - 1.1e-15 57.8 0.0 3e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71470.1 - 5.5e-12 45.6 0.0 1.7e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG71470.1 - 5.4e-07 29.5 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG71470.1 - 1.1e-06 28.8 0.1 4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG71470.1 - 8.3e-06 26.3 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71470.1 - 4.8e-05 23.9 0.0 8.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71470.1 - 0.0038 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG71471.1 - 6.7e-34 115.9 0.0 1.2e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71471.1 - 7.2e-26 90.5 0.2 1.8e-25 89.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71471.1 - 2.4e-23 82.8 0.0 4.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1635 PF07795.11 GBG71471.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) RT_RNaseH PF17917.1 GBG71472.1 - 2.9e-27 95.0 0.1 7.5e-27 93.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71472.1 - 2.4e-20 72.4 0.1 1.2e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG71472.1 - 0.00012 22.6 0.0 0.00044 20.7 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG71472.1 - 0.002 17.9 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG71472.1 - 0.0035 17.6 0.3 0.83 10.0 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF1758 PF05585.12 GBG71472.1 - 0.0086 15.9 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG71472.1 - 0.011 16.4 0.0 0.06 14.0 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC_3 PF13917.6 GBG71472.1 - 0.053 13.5 1.2 0.13 12.2 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG71473.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PIP5K PF01504.18 GBG71474.1 - 3e-85 285.8 0.0 8.8e-85 284.2 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MORN PF02493.20 GBG71474.1 - 1.4e-43 144.2 54.8 4.2e-06 26.3 0.8 9.1 8 0 0 8 8 8 8 MORN repeat ThiP_synth PF10120.9 GBG71475.1 - 0.056 13.1 0.1 0.063 12.9 0.1 1.1 1 0 0 1 1 1 0 Thiamine-phosphate synthase P53_C PF11619.8 GBG71475.1 - 0.087 12.9 0.1 0.85 9.7 0.0 2.1 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain zf-C3HC4_3 PF13920.6 GBG71476.1 - 8.6e-16 57.5 12.3 1.2e-15 57.1 12.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG71476.1 - 7.1e-08 32.2 11.5 1.2e-07 31.5 11.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GBG71476.1 - 4.9e-07 30.0 12.2 7.4e-07 29.4 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG71476.1 - 0.003 17.5 11.7 0.0069 16.3 11.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GBG71476.1 - 0.0072 16.1 12.4 0.011 15.6 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG71476.1 - 0.1 12.7 6.1 0.21 11.6 3.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 GBG71476.1 - 0.55 10.1 10.0 0.99 9.2 10.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 GBG71476.1 - 1.5 8.6 10.5 2.3 7.9 10.5 1.3 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_3 PF13920.6 GBG71477.1 - 1.6e-15 56.7 12.7 2.2e-15 56.2 12.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG71477.1 - 7.1e-08 32.2 11.5 1.2e-07 31.5 11.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GBG71477.1 - 4.5e-07 30.1 12.1 6.7e-07 29.5 12.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG71477.1 - 0.0045 16.9 12.2 0.008 16.1 12.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GBG71477.1 - 0.0071 16.2 12.4 0.011 15.6 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG71477.1 - 0.098 12.7 6.1 0.21 11.7 3.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 GBG71477.1 - 0.4 10.5 9.6 0.72 9.7 9.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RVT_1 PF00078.27 GBG71479.1 - 3.1e-26 92.3 0.0 5.2e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG71479.1 - 3.7e-06 26.8 3.2 6.8e-06 25.9 3.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG71479.1 - 0.25 11.2 4.6 0.48 10.3 4.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Syntaxin_2 PF14523.6 GBG71479.1 - 0.36 11.2 1.5 3.6 8.0 0.1 2.5 2 0 0 2 2 2 0 Syntaxin-like protein Trypsin PF00089.26 GBG71481.1 - 4.7e-30 105.0 0.0 1.1e-29 103.8 0.0 1.6 1 0 0 1 1 1 1 Trypsin Pkinase PF00069.25 GBG71482.1 - 0.00028 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Herpes_BLRF2 PF05812.12 GBG71483.1 - 0.014 15.5 1.3 0.063 13.4 0.3 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Med3 PF11593.8 GBG71483.1 - 1.1 8.3 10.8 0.069 12.3 5.7 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal GCN5L1 PF06320.13 GBG71483.1 - 10 6.3 8.7 1.3 9.2 0.0 2.9 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) RT_RNaseH PF17917.1 GBG71484.1 - 8.9e-18 64.5 0.2 1.5e-17 63.8 0.2 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71484.1 - 1.7e-09 37.6 0.1 2.9e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Skp1 PF01466.19 GBG71485.1 - 8.4e-13 48.2 0.1 2.1e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GBG71485.1 - 2.5e-07 30.8 0.0 6.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain ESM4 PF15952.5 GBG71485.1 - 0.15 12.4 12.8 0.36 11.2 12.8 1.5 1 0 0 1 1 1 0 Enhancer of split M4 family UPF0524 PF15823.5 GBG71485.1 - 0.86 9.0 4.7 1.7 8.0 4.7 1.4 1 0 0 1 1 1 0 UPF0524 of C3orf70 LMBR1 PF04791.16 GBG71485.1 - 3.7 6.4 3.6 5.8 5.7 3.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 GBG71485.1 - 4.7 5.0 9.4 8.3 4.2 9.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 GBG71485.1 - 6.2 6.9 9.2 0.41 10.8 3.0 2.0 2 0 0 2 2 2 0 DDHD domain TERB2 PF15101.6 GBG71485.1 - 9.4 6.2 15.8 21 5.1 15.8 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Cation_ATPase_C PF00689.21 GBG71486.1 - 7.4e-51 172.4 1.3 7.4e-51 172.4 1.3 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GBG71486.1 - 1.7e-48 164.6 2.0 2e-48 164.3 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 GBG71486.1 - 5.6e-21 74.0 0.0 1e-18 66.8 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 GBG71486.1 - 1.3e-17 64.8 2.6 4.6e-14 53.2 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GBG71486.1 - 8e-15 54.7 0.0 1.5e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GBG71486.1 - 0.00013 21.9 1.4 0.00059 19.7 1.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GBG71486.1 - 0.00097 19.6 0.1 0.0063 16.9 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase BLOC1S3 PF15753.5 GBG71486.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 ribosomal_L24 PF17136.4 GBG71487.1 - 2e-20 73.0 0.4 2e-20 73.0 0.4 2.0 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 GBG71487.1 - 7.6e-07 28.9 6.1 7e-06 25.8 2.7 3.0 3 0 0 3 3 3 1 KOW motif RT_RNaseH PF17917.1 GBG71489.1 - 4.8e-22 78.2 0.0 1.1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71489.1 - 6.7e-21 74.2 0.0 1.6e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Topo_Zn_Ribbon PF08272.11 GBG71489.1 - 0.045 13.4 0.3 0.14 11.8 0.3 1.9 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG71489.1 - 0.12 12.6 1.9 0.27 11.4 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle SF3b10 PF07189.11 GBG71490.1 - 2.2e-35 120.6 0.0 2.4e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) UCR_14kD PF02271.16 GBG71491.1 - 9.7e-27 92.9 4.0 1.2e-26 92.6 4.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF4136 PF13590.6 GBG71491.1 - 0.018 15.6 0.4 5.3 7.6 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4136) Aminotran_1_2 PF00155.21 GBG71492.1 - 2.3e-35 122.5 0.0 2.7e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GBG71492.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GBG71492.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 GBG71492.1 - 0.086 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V SDA1 PF05285.12 GBG71493.1 - 0.023 14.2 27.5 0.029 13.8 27.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG71493.1 - 0.053 11.8 22.7 0.072 11.4 22.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG71493.1 - 0.27 9.4 31.3 0.34 9.1 31.3 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG71493.1 - 0.72 9.1 30.7 1.1 8.6 30.7 1.2 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 GBG71493.1 - 0.82 9.0 23.0 1.3 8.4 23.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIF_alpha PF05793.12 GBG71493.1 - 2 6.9 29.5 4 5.9 29.5 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LAP1C PF05609.12 GBG71493.1 - 2.1 7.4 16.7 2.6 7.1 16.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Lin-8 PF03353.15 GBG71493.1 - 2.6 7.5 20.0 3.7 7.0 20.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 GBG71493.1 - 2.7 7.1 7.7 3.5 6.7 7.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 GBG71493.1 - 3.5 5.9 33.2 4.8 5.5 33.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Presenilin PF01080.17 GBG71493.1 - 4.2 6.0 18.0 5.3 5.7 18.0 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GBG71493.1 - 4.5 7.0 23.1 7.7 6.3 23.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cation_efflux PF01545.21 GBG71494.1 - 4.7e-35 121.1 38.4 4.7e-35 121.1 38.4 3.5 2 2 1 3 3 3 1 Cation efflux family RVT_1 PF00078.27 GBG71494.1 - 0.029 13.9 0.1 0.078 12.5 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF420 PF04238.12 GBG71494.1 - 3.8 7.8 9.1 0.15 12.3 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF420) Branch PF02485.21 GBG71497.1 - 1.3e-57 195.2 0.2 1.6e-57 194.8 0.2 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme adh_short PF00106.25 GBG71498.1 - 7.2e-29 100.6 0.0 1.8e-28 99.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG71498.1 - 1.4e-14 54.3 0.1 3e-14 53.1 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG71498.1 - 6.9e-09 35.9 0.3 1.4e-08 34.8 0.3 1.5 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 GBG71498.1 - 0.053 12.7 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GBG71498.1 - 0.11 12.6 0.3 0.17 12.0 0.3 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 GBG71498.1 - 0.16 11.2 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RVT_1 PF00078.27 GBG71499.1 - 3e-29 102.1 0.0 4.4e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71499.1 - 1.1e-14 54.3 0.0 2.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71499.1 - 3.6e-05 24.0 0.0 7.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HSP70 PF00012.20 GBG71501.1 - 7.9e-108 361.2 0.6 9.1e-108 361.0 0.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG71501.1 - 1.8e-10 40.2 1.2 2.7e-09 36.3 0.5 2.1 2 0 0 2 2 2 2 MreB/Mbl protein HSP70 PF00012.20 GBG71502.1 - 5.1e-259 860.5 5.3 5.8e-259 860.3 5.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG71502.1 - 3.7e-16 58.9 0.4 2.9e-15 55.9 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG71502.1 - 0.00024 20.9 0.0 0.00059 19.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 GBG71502.1 - 0.028 13.4 0.2 0.37 9.7 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Radial_spoke_3 PF06098.11 GBG71502.1 - 0.23 10.7 5.0 0.38 10.0 5.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 HSP70 PF00012.20 GBG71503.1 - 6.7e-262 870.0 5.8 7.6e-262 869.8 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG71503.1 - 7.2e-17 61.2 0.3 5.8e-16 58.2 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG71503.1 - 0.001 18.8 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 GBG71503.1 - 0.013 14.8 5.7 0.02 14.2 5.7 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 DDR PF08841.10 GBG71503.1 - 0.027 13.5 0.2 0.34 9.8 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain CRIC_ras_sig PF10534.9 GBG71503.1 - 0.065 13.4 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras Erg28 PF03694.13 GBG71504.1 - 1.2e-22 80.3 3.9 2e-22 79.7 3.9 1.3 1 0 0 1 1 1 1 Erg28 like protein Bot1p PF12298.8 GBG71504.1 - 3.1e-05 24.2 0.1 3.1e-05 24.2 0.1 2.3 3 0 0 3 3 3 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 GBG71504.1 - 5e-05 23.5 1.6 0.00016 21.9 1.6 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 GBG71504.1 - 0.00045 20.3 0.3 0.0015 18.6 0.1 1.9 2 0 0 2 2 2 1 Neugrin UPF0240 PF06784.11 GBG71504.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Cpn60_TCP1 PF00118.24 GBG71505.1 - 6.5e-91 305.4 19.7 2.7e-78 263.8 17.3 2.5 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family NUSAP PF16006.5 GBG71506.1 - 0.088 12.6 3.1 0.23 11.2 3.1 1.7 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein LAGLIDADG_2 PF03161.13 GBG71507.1 - 5.2e-18 65.6 0.0 1.2e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 LAGLIDADG DNA endonuclease family PPR PF01535.20 GBG71507.1 - 3.2e-13 48.9 0.0 0.1 12.9 0.0 7.2 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 GBG71507.1 - 7.6e-11 41.8 4.2 2.3e-05 23.9 0.1 3.5 2 2 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 GBG71507.1 - 6.9e-07 29.4 0.0 1.7 8.9 0.0 5.4 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.6 GBG71507.1 - 8.6e-06 25.8 0.0 0.28 11.3 0.0 4.8 4 0 0 4 4 4 1 Pentatricopeptide repeat domain TPR_14 PF13428.6 GBG71507.1 - 1.8 9.6 17.4 5.1 8.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 GBG71508.1 - 5.1e-23 81.0 0.0 1.4e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71508.1 - 1.6e-17 63.3 0.8 3.5e-17 62.2 0.8 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG71508.1 - 7.1e-14 52.0 0.0 1.9e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG71508.1 - 4.3e-07 30.1 0.0 1.3e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG71508.1 - 0.0001 22.8 0.0 0.0004 20.9 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71508.1 - 0.00033 21.2 0.0 0.00077 20.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71508.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG71508.1 - 0.0036 16.8 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG71508.1 - 0.015 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG71508.1 - 0.068 13.4 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG71509.1 - 2.8e-07 31.0 0.1 9.9e-07 29.2 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71509.1 - 1.2e-05 25.9 0.4 3e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG71509.1 - 0.00077 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71509.1 - 0.018 14.8 0.1 0.039 13.7 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG71509.1 - 0.039 14.0 1.9 0.069 13.3 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG71509.1 - 0.15 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like N_formyltrans_C PF18216.1 GBG71510.1 - 0.086 12.5 0.2 0.39 10.4 0.1 2.1 2 0 0 2 2 2 0 N-formyltransferase dimerization C-terminal domain Spc42p PF11544.8 GBG71510.1 - 0.96 9.5 6.1 11 6.1 0.3 3.1 2 1 1 3 3 3 0 Spindle pole body component Spc42p Histidinol_dh PF00815.20 GBG71511.1 - 3.5e-160 533.5 1.1 4.2e-160 533.2 1.1 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase Ribosomal_L1 PF00687.21 GBG71512.1 - 2.3e-20 73.2 0.0 3.7e-18 66.0 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L1p/L10e family RVT_1 PF00078.27 GBG71513.1 - 4.1e-34 118.0 0.1 8.2e-34 117.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71513.1 - 1.1e-30 105.6 0.0 4.4e-30 103.7 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71513.1 - 2.1e-30 105.1 0.4 1.3e-29 102.6 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71513.1 - 1.4e-17 63.5 0.5 3e-17 62.4 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71513.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71513.1 - 0.0065 16.7 0.0 0.027 14.7 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG71513.1 - 0.26 10.9 0.1 0.26 10.9 0.1 3.2 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase SET PF00856.28 GBG71514.1 - 1.9e-18 67.4 0.0 1.3e-17 64.7 0.0 2.3 1 1 0 1 1 1 1 SET domain DUF2052 PF09747.9 GBG71514.1 - 0.038 14.1 9.6 0.054 13.6 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Herpes_UL4 PF03277.13 GBG71514.1 - 0.085 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL4 family CobT PF06213.12 GBG71514.1 - 2.4 7.4 17.0 0.28 10.5 0.4 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Phage_integrase PF00589.22 GBG71515.1 - 2.9e-05 23.9 0.0 4.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Na_sulph_symp PF00939.19 GBG71516.1 - 8.6e-141 470.2 36.4 1.1e-140 469.8 36.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GBG71516.1 - 4.9e-19 68.7 49.2 3.5e-15 56.0 27.0 2.5 1 1 1 2 2 2 2 Citrate transporter zf-CCHC PF00098.23 GBG71517.1 - 2.9e-05 23.9 3.0 6.3e-05 22.9 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG71517.1 - 0.0018 18.1 2.8 0.0031 17.3 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle TMEM214 PF10151.9 GBG71517.1 - 9.8 4.5 7.6 17 3.7 7.6 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator zf-CCHC_3 PF13917.6 GBG71518.1 - 0.001 19.0 0.9 0.002 18.0 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG71518.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein rve PF00665.26 GBG71519.1 - 1.8e-08 34.6 0.1 3.1e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG71519.1 - 4e-05 23.4 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG71520.1 - 3.2e-29 100.9 0.0 7.1e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71520.1 - 5e-27 94.3 0.0 8.7e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71520.1 - 9.1e-14 51.5 0.1 1.3e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mpp10 PF04006.12 GBG71520.1 - 0.5 8.8 42.0 0.79 8.1 42.0 1.3 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 GBG71520.1 - 0.88 8.1 39.3 1.3 7.6 39.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 GBG71520.1 - 1.1 8.6 46.4 1.9 7.8 46.4 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG71520.1 - 1.7 7.9 49.8 2.9 7.1 49.8 1.2 1 0 0 1 1 1 0 BUD22 Plasmodium_Vir PF05795.11 GBG71520.1 - 5.3 6.4 14.0 8.2 5.7 14.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 GBG71520.1 - 6.2 5.5 21.7 9.4 4.9 21.7 1.3 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 GBG71521.1 - 2.9e-14 53.1 0.2 1.3e-11 44.4 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71521.1 - 1.4e-07 31.1 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GRP PF07172.11 GBG71521.1 - 0.00035 21.2 22.7 0.00035 21.2 22.7 5.8 5 1 1 6 6 6 1 Glycine rich protein family Radial_spoke PF04712.12 GBG71521.1 - 6.4 5.6 8.5 10 4.9 8.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Fasciclin PF02469.22 GBG71522.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Fasciclin domain DUF659 PF04937.15 GBG71523.1 - 5e-29 101.1 0.3 9.7e-29 100.2 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71523.1 - 5.7e-05 22.8 0.5 0.00021 21.0 0.3 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region GcnA_N PF18229.1 GBG71524.1 - 0.043 13.9 0.1 0.15 12.1 0.1 2.0 1 1 0 1 1 1 0 N-acetyl-beta-D-glucosaminidase N-terminal domain MAGE PF01454.19 GBG71525.1 - 3.9e-29 101.9 0.0 6.5e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 MAGE family Ribosomal_L31 PF01197.18 GBG71525.1 - 0.038 14.2 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L31 CLP_protease PF00574.23 GBG71526.1 - 8.9e-60 201.7 0.0 1.3e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease RT_RNaseH_2 PF17919.1 GBG71527.1 - 5.4e-29 100.2 0.0 1.2e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71527.1 - 2.8e-18 66.1 0.0 8.2e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Laminin_G_3 PF13385.6 GBG71527.1 - 1.8e-15 57.4 0.0 3.1e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF2866 PF11065.8 GBG71527.1 - 0.0015 18.5 0.4 0.66 10.0 0.2 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2866) Laminin_G_2 PF02210.24 GBG71527.1 - 0.003 18.1 0.0 0.0061 17.1 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Flavi_NS1 PF00948.21 GBG71527.1 - 0.088 11.7 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 CDC27 PF09507.10 GBG71527.1 - 0.11 11.9 15.9 0.15 11.4 15.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Myc_N PF01056.18 GBG71527.1 - 0.12 12.2 10.1 0.17 11.8 9.4 1.5 1 1 0 1 1 1 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 GBG71527.1 - 1.7 8.9 12.7 3.9 7.7 12.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PBP_sp32 PF07222.12 GBG71527.1 - 9.9 5.5 10.7 23 4.4 10.7 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Glycos_transf_2 PF00535.26 GBG71528.1 - 1.8e-31 109.3 0.1 3.4e-31 108.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 RT_RNaseH_2 PF17919.1 GBG71528.1 - 2.3e-24 85.3 0.0 4.4e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71528.1 - 1.9e-22 79.6 0.0 3.3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71528.1 - 1.3e-16 60.5 1.7 1.8e-15 56.8 0.5 3.0 3 0 0 3 3 3 1 Integrase zinc binding domain Glyco_tranf_2_3 PF13641.6 GBG71528.1 - 1.8e-14 54.2 0.1 3.3e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GBG71528.1 - 2.6e-12 46.8 0.1 2.4e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 RVT_1 PF00078.27 GBG71528.1 - 1.9e-09 37.3 0.1 3.3e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_tranf_2_4 PF13704.6 GBG71528.1 - 2e-06 28.2 0.1 1.6e-05 25.3 0.1 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 zf-H2C2 PF09337.10 GBG71528.1 - 0.0061 16.8 0.4 0.017 15.3 0.4 1.8 1 0 0 1 1 1 1 H2C2 zinc finger TPR_11 PF13414.6 GBG71528.1 - 0.094 12.4 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 TPR repeat TPR_6 PF13174.6 GBG71528.1 - 0.12 13.1 1.1 9.2 7.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG71528.1 - 0.25 11.2 1.7 1.2 9.1 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_4 PF12763.7 GBG71529.1 - 2.5e-05 24.2 0.0 0.0058 16.6 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 GBG71529.1 - 2.6e-05 23.4 0.0 0.069 12.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GBG71529.1 - 0.006 16.4 0.0 1.4 9.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GBG71529.1 - 0.01 16.3 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 GBG71529.1 - 0.15 12.0 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair ATP-grasp PF02222.22 GBG71530.1 - 2.4e-58 196.5 0.0 5.6e-58 195.3 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain AIRC PF00731.20 GBG71530.1 - 3.9e-36 123.9 3.5 2.7e-29 101.7 0.4 3.0 2 1 1 3 3 3 2 AIR carboxylase PurK_C PF17769.1 GBG71530.1 - 3.6e-20 71.4 0.1 7.2e-20 70.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 GBG71530.1 - 0.00012 21.7 0.0 0.00058 19.5 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 GBG71530.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 GBG71530.1 - 0.021 14.9 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp domain XdhC_C PF13478.6 GBG71530.1 - 0.054 14.0 0.9 1.5 9.4 0.0 3.3 3 0 0 3 3 3 0 XdhC Rossmann domain AhpC-TSA PF00578.21 GBG71531.1 - 5.6e-26 90.9 0.0 7.1e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GBG71531.1 - 2.5e-13 50.0 0.0 3.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GBG71531.1 - 7.5e-13 48.1 0.0 1.6e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 GBG71531.1 - 0.00052 20.1 0.0 0.00066 19.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme UAA PF08449.11 GBG71532.1 - 3.9e-58 197.1 17.9 5.1e-58 196.7 17.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GBG71532.1 - 0.0028 17.8 25.3 0.0051 17.0 12.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family TMEM173 PF15009.6 GBG71532.1 - 1.8 7.6 4.2 7.1 5.7 0.1 2.4 2 1 0 2 2 2 0 Transmembrane protein 173 HECT PF00632.25 GBG71533.1 - 1.5e-92 310.3 0.0 2.2e-92 309.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 GBG71533.1 - 3.5e-82 276.3 0.0 6.8e-80 268.8 0.0 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 GBG71533.1 - 2.1e-35 122.8 0.0 2.1e-34 119.5 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) UBM PF14377.6 GBG71533.1 - 3.2e-20 70.8 32.9 6.6e-09 34.9 2.5 6.9 5 1 1 6 6 6 3 Ubiquitin binding region UBA PF00627.31 GBG71533.1 - 5.7e-06 26.1 0.0 1.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF1461 PF07314.11 GBG71534.1 - 0.0025 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1461) zf-CCHC_2 PF13696.6 GBG71534.1 - 0.027 14.3 2.8 0.053 13.3 2.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG71534.1 - 0.35 11.0 2.5 0.71 10.1 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1664 PF07889.12 GBG71534.1 - 2 8.4 5.1 2.1 8.4 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2201_N PF13203.6 GBG71534.1 - 5.2 6.6 0.0 5.2 6.6 0.0 3.6 3 1 1 4 4 4 0 Putative metallopeptidase domain DDE_Tnp_4 PF13359.6 GBG71536.1 - 1.5e-30 105.9 0.0 2.8e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71536.1 - 2.1e-14 53.6 0.0 3.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein RVT_1 PF00078.27 GBG71536.1 - 6.6e-09 35.6 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG71536.1 - 0.00048 19.7 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DDE_Tnp_1 PF01609.21 GBG71536.1 - 0.0019 17.9 0.1 2.5 7.7 0.1 2.5 2 0 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG71537.1 - 3.6e-08 33.7 0.3 7.4e-08 32.7 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG71537.1 - 0.017 15.2 0.4 0.038 14.1 0.4 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG71538.1 - 3.9e-36 123.1 0.0 7.3e-36 122.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71538.1 - 9.6e-30 103.0 0.0 1.7e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71538.1 - 5.6e-24 84.9 0.0 9.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71538.1 - 1.6e-10 40.9 0.1 3.6e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-C3HC4_3 PF13920.6 GBG71540.1 - 1.5e-14 53.6 16.4 2.1e-14 53.1 16.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG71540.1 - 3.3e-07 30.5 15.3 5e-07 29.9 15.3 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GBG71540.1 - 2.3e-06 27.4 15.8 3.5e-06 26.8 15.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GBG71540.1 - 0.0024 17.7 15.3 0.0038 17.0 15.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG71540.1 - 0.01 15.8 16.8 0.017 15.1 16.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 GBG71540.1 - 1 9.1 10.0 1.8 8.3 10.0 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 GBG71540.1 - 2.2 8.1 14.4 4.1 7.3 14.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain bZIP_1 PF00170.21 GBG71541.1 - 6.7e-12 45.3 21.5 5.6e-10 39.2 14.4 2.4 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 GBG71541.1 - 0.00032 20.7 17.7 0.00032 20.7 17.7 2.4 1 1 1 2 2 2 1 Basic region leucine zipper HAP1_N PF04849.13 GBG71541.1 - 0.032 13.5 7.4 0.048 12.9 7.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_Maf PF03131.17 GBG71541.1 - 0.099 13.2 14.3 0.13 12.8 13.0 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor RT_RNaseH_2 PF17919.1 GBG71543.1 - 1.7e-33 114.7 0.0 4.1e-33 113.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71543.1 - 1.5e-29 102.4 0.2 3.1e-29 101.3 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71543.1 - 7.4e-11 42.0 0.1 1.5e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG71543.1 - 0.0091 15.7 1.0 0.036 13.8 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) rve PF00665.26 GBG71543.1 - 0.11 12.7 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain Nop14 PF04147.12 GBG71544.1 - 0.031 12.5 50.4 0.037 12.3 50.4 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG71544.1 - 0.16 10.3 52.4 0.22 10.0 52.4 1.3 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 GBG71544.1 - 0.28 10.5 52.7 0.33 10.2 52.7 1.0 1 0 0 1 1 1 0 BUD22 Caldesmon PF02029.15 GBG71544.1 - 0.35 9.6 47.2 0.48 9.1 47.2 1.2 1 0 0 1 1 1 0 Caldesmon SDA1 PF05285.12 GBG71544.1 - 0.87 9.0 57.3 1.3 8.4 57.3 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG71544.1 - 2.5 6.3 45.3 4.1 5.6 45.3 1.4 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 GBG71544.1 - 3.6 6.3 30.4 4.5 5.9 30.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 GBG71544.1 - 4.9 5.6 20.5 5.6 5.4 20.5 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 GBG71544.1 - 5.2 5.7 33.7 6.1 5.5 33.7 1.1 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.12 GBG71544.1 - 7.5 6.2 49.3 9.7 5.8 49.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4045 PF13254.6 GBG71544.1 - 8.7 5.9 30.8 9.9 5.7 30.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Lin-8 PF03353.15 GBG71544.1 - 9.6 5.7 34.8 12 5.4 34.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RT_RNaseH_2 PF17919.1 GBG71545.1 - 4.4e-19 68.4 0.0 1.4e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71545.1 - 7.8e-08 32.6 0.0 1.9e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71545.1 - 2.6e-07 30.4 0.0 3.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG71545.1 - 2 7.8 20.6 2.8 7.3 20.6 1.1 1 0 0 1 1 1 0 SDA1 NAD_binding_10 PF13460.6 GBG71546.1 - 1.4e-30 106.5 0.0 2e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GBG71546.1 - 3.1e-07 30.2 0.1 5.4e-06 26.1 0.1 2.5 1 1 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 GBG71546.1 - 0.012 15.7 0.1 0.024 14.8 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 GBG71546.1 - 0.096 11.7 0.0 0.55 9.2 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF659 PF04937.15 GBG71547.1 - 4.7e-11 42.8 0.7 3.6e-08 33.4 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF 659) Benyvirus_P25 PF05744.11 GBG71547.1 - 0.031 13.6 0.2 0.048 13.0 0.2 1.3 1 0 0 1 1 1 0 Benyvirus P25/P26 protein RT_RNaseH PF17917.1 GBG71548.1 - 1.4e-21 76.7 0.0 2.6e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71548.1 - 9.5e-20 70.5 0.0 2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71548.1 - 3.3e-13 49.5 0.5 7.3e-13 48.4 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG71548.1 - 1.7e-06 28.2 0.0 4.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71548.1 - 0.0029 17.8 0.0 0.0073 16.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG71548.1 - 0.029 14.7 0.0 0.11 12.7 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG71549.1 - 6.9e-06 26.5 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71549.1 - 0.00022 21.8 0.0 0.00043 20.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-C2H2_10 PF16588.5 GBG71549.1 - 0.67 9.7 3.3 1.7 8.5 3.3 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger DUF659 PF04937.15 GBG71550.1 - 6e-19 68.4 0.0 1.1e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71550.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region LRR_6 PF13516.6 GBG71551.1 - 1.7e-19 68.1 17.3 5.2e-05 23.0 0.0 12.3 13 0 0 13 13 13 4 Leucine Rich repeat F-box-like PF12937.7 GBG71551.1 - 5.1e-08 32.7 0.6 1.4e-07 31.3 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 GBG71551.1 - 7.3e-06 25.5 0.6 1.6e-05 24.4 0.6 1.6 1 0 0 1 1 1 1 F-box LRR_4 PF12799.7 GBG71551.1 - 0.00015 22.1 0.0 15 6.2 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG71551.1 - 0.0031 17.4 1.6 0.011 15.6 1.6 2.0 1 0 0 1 1 1 1 F-box domain DUF945 PF06097.11 GBG71551.1 - 0.22 10.6 0.6 0.33 10.0 0.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Ins_beta PF03488.14 GBG71551.1 - 0.26 11.3 8.1 0.12 12.5 0.7 3.1 3 0 0 3 3 3 0 Nematode insulin-related peptide beta type SPX PF03105.19 GBG71551.1 - 9.8 6.0 13.9 22 4.8 13.9 1.6 1 0 0 1 1 1 0 SPX domain RVT_1 PF00078.27 GBG71554.1 - 1.6e-22 80.1 0.0 3.3e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG71554.1 - 0.21 12.2 0.0 0.57 10.9 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease YL1 PF05764.13 GBG71555.1 - 0.043 13.9 18.4 0.056 13.5 18.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GBG71555.1 - 0.066 12.6 19.3 0.076 12.4 19.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG71555.1 - 0.12 10.6 15.5 0.15 10.4 15.5 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG71555.1 - 0.16 11.3 20.7 0.21 10.9 20.7 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG71555.1 - 0.63 9.5 9.7 0.78 9.3 9.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG71555.1 - 1.2 7.3 22.3 1.4 7.0 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG71555.1 - 1.8 8.3 13.8 2.7 7.7 13.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG71555.1 - 2 7.1 8.1 2.7 6.7 8.1 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 GBG71555.1 - 9.1 5.0 7.4 12 4.6 7.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 GBG71555.1 - 9.8 4.2 6.8 10 4.1 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-CCHC PF00098.23 GBG71556.1 - 0.072 13.2 3.4 0.12 12.5 3.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG71557.1 - 0.0019 18.4 0.2 0.0019 18.4 0.2 2.8 4 0 0 4 4 4 1 Retrotransposon gag protein CENP-K PF11802.8 GBG71557.1 - 0.022 14.4 2.2 0.043 13.4 2.2 1.4 1 0 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 GBG71557.1 - 0.15 12.0 11.0 0.22 11.5 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asp_protease_2 PF13650.6 GBG71558.1 - 2.1e-05 25.1 0.0 6.1e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71558.1 - 7.5e-05 23.2 0.0 0.00021 21.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG71558.1 - 0.0015 18.7 0.2 0.0063 16.8 0.2 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG71558.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71558.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG71559.1 - 2.1e-05 25.1 0.0 6.2e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71559.1 - 7.5e-05 23.2 0.0 0.00021 21.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG71559.1 - 0.0016 18.7 0.2 0.0063 16.8 0.2 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG71559.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71559.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG71560.1 - 2.1e-05 25.1 0.0 6.2e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71560.1 - 7.5e-05 23.2 0.0 0.00021 21.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG71560.1 - 0.0015 18.7 0.2 0.0063 16.8 0.2 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG71560.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71560.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Mitoc_mL59 PF18126.1 GBG71561.1 - 4.6e-07 30.2 1.8 5e-07 30.1 1.8 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 TBCC PF07986.12 GBG71562.1 - 4.3e-32 110.4 0.0 1.1e-31 109.1 0.0 1.7 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 GBG71562.1 - 1.7e-18 67.1 2.5 1.7e-18 67.1 2.5 2.3 2 0 0 2 2 1 1 Tubulin-specific chaperone C N-terminal domain MTS PF05175.14 GBG71562.1 - 1.5e-08 34.3 0.0 5.2e-08 32.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GBG71562.1 - 1.7e-07 31.2 0.0 4.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GBG71562.1 - 1.8e-07 30.9 0.0 2.3e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GBG71562.1 - 7.1e-05 23.4 0.0 0.00023 21.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GBG71562.1 - 0.0001 22.0 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 FAM176 PF14851.6 GBG71562.1 - 0.00041 20.0 0.6 0.00095 18.8 0.6 1.6 1 0 0 1 1 1 1 FAM176 family Methyltransf_15 PF09445.10 GBG71562.1 - 0.00043 19.9 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 GBG71562.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG71562.1 - 0.0063 17.1 0.0 0.054 14.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain NOA36 PF06524.12 GBG71562.1 - 6.3 6.0 15.0 14 4.9 15.0 1.5 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 GBG71562.1 - 8.2 6.9 10.2 22 5.5 10.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ada3 PF10198.9 GBG71563.1 - 2.3e-07 31.0 2.4 8.8e-07 29.1 2.4 2.0 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DDE_Tnp_4 PF13359.6 GBG71566.1 - 1.5e-11 44.2 0.2 2.9e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71566.1 - 0.00038 20.1 0.0 0.00071 19.2 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein Pkinase_Tyr PF07714.17 GBG71568.1 - 1.2e-46 159.1 0.0 1.9e-44 151.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG71568.1 - 5.4e-42 144.0 0.0 8.9e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LysM PF01476.20 GBG71568.1 - 1.5e-15 56.9 0.0 9.7e-05 22.3 0.0 3.4 3 0 0 3 3 3 3 LysM domain PIP49_C PF12260.8 GBG71568.1 - 0.004 16.8 0.0 0.004 16.8 0.0 1.7 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 APH PF01636.23 GBG71568.1 - 0.0053 16.7 0.1 0.32 10.9 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG71568.1 - 0.025 13.3 0.0 0.025 13.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase MSP1a PF11670.8 GBG71568.1 - 0.24 10.7 9.9 1 8.6 0.1 3.3 3 0 0 3 3 3 0 Major surface protein 1a (MSP1a) DUF659 PF04937.15 GBG71569.1 - 1.6e-11 44.3 0.0 2.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) BLM_N PF16202.5 GBG71569.1 - 0.15 11.1 1.9 0.24 10.5 1.9 1.2 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein Ribosomal_S4e PF00900.20 GBG71570.1 - 1.1e-33 114.9 0.2 2.9e-33 113.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 GBG71570.1 - 8.2e-23 79.8 0.0 2.7e-22 78.1 0.0 1.9 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 GBG71570.1 - 1.7e-20 72.8 4.4 3.2e-20 71.9 4.4 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 GBG71570.1 - 6.3e-08 32.3 1.3 1.7e-07 31.0 1.3 1.8 1 0 0 1 1 1 1 KOW motif S4 PF01479.25 GBG71570.1 - 1.5e-06 27.8 0.0 3.4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 S4 domain Sipho_tail PF05709.11 GBG71570.1 - 0.12 11.8 0.0 0.48 9.8 0.0 1.6 1 1 1 2 2 2 0 Phage tail protein Peptidase_S24 PF00717.23 GBG71571.1 - 5.1e-11 42.4 0.4 7.2e-11 41.9 0.4 1.3 1 0 0 1 1 1 1 Peptidase S24-like Ribosomal_L7Ae PF01248.26 GBG71573.1 - 1.8e-27 94.9 0.5 2.4e-27 94.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 GBG71573.1 - 0.0014 18.7 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 VirionAssem_T7 PF11653.8 GBG71573.1 - 0.6 10.6 5.9 0.31 11.6 1.8 2.0 1 1 1 2 2 2 0 Bacteriophage T7 virion assembly protein Trp_oprn_chp PF09534.10 GBG71574.1 - 2.6 7.8 8.1 1.5 8.6 0.7 2.2 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4418 PF14387.6 GBG71574.1 - 7.8 6.7 13.4 0.49 10.6 7.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) XPG_I PF00867.18 GBG71575.1 - 2.5e-21 75.8 0.1 5.3e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GBG71575.1 - 8.5e-06 26.2 0.0 4.5e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 GBG71575.1 - 0.0025 17.3 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Ribosomal_L41 PF05162.13 GBG71576.1 - 9.1e-11 41.6 32.2 1.5e-10 40.9 32.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1336 PF07059.12 GBG71577.1 - 1.1e-58 199.1 0.0 7.8e-58 196.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1336) PH PF00169.29 GBG71578.1 - 0.035 14.6 0.0 0.095 13.2 0.0 1.7 1 1 0 1 1 1 0 PH domain Patatin PF01734.22 GBG71579.1 - 1.3e-21 77.7 0.0 2.4e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Arm PF00514.23 GBG71579.1 - 1.5e-06 28.0 0.9 0.044 13.8 0.1 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat TBP PF00352.21 GBG71579.1 - 0.12 12.3 0.0 4.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIID (or TATA-binding protein, TBP) LRR_4 PF12799.7 GBG71581.1 - 2.7e-15 56.2 9.5 1.7e-06 28.3 0.7 3.3 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG71581.1 - 8.3e-08 31.9 11.0 3.9e-06 26.5 1.4 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 GBG71581.1 - 0.0055 17.1 10.6 2.7 8.9 0.1 5.5 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 GBG71581.1 - 7.1 7.0 8.2 28 5.1 0.3 4.4 5 0 0 5 5 5 0 Leucine Rich repeat Rgp1 PF08737.10 GBG71582.1 - 1.8e-25 90.0 0.0 1.1e-15 57.8 0.0 2.6 3 0 0 3 3 3 2 Rgp1 COX17 PF05051.13 GBG71582.1 - 3.4e-16 59.3 8.9 6.2e-16 58.5 8.9 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Astro_capsid_p PF12226.8 GBG71582.1 - 0.11 11.7 2.7 0.17 11.0 2.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EP400_N PF15790.5 GBG71582.1 - 0.36 9.6 0.0 0.36 9.6 0.0 1.9 2 0 0 2 2 2 0 E1A-binding protein p400, N-terminal CDC45 PF02724.14 GBG71582.1 - 0.49 8.6 4.8 0.71 8.1 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 GBG71582.1 - 2.8 7.2 12.1 4.8 6.5 12.1 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GBG71582.1 - 3.7 5.6 5.5 5.1 5.2 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.12 GBG71582.1 - 9.8 5.0 9.2 15 4.4 9.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Lycopene_cycl PF05834.12 GBG71583.1 - 2.9e-106 355.8 0.2 5.9e-105 351.4 0.2 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GBG71583.1 - 1.6e-05 24.3 0.1 0.019 14.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GBG71583.1 - 5.8e-05 22.8 0.4 0.0018 17.9 0.0 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GBG71583.1 - 7.4e-05 22.2 0.0 0.00059 19.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GBG71583.1 - 0.00018 20.8 1.4 0.23 10.7 0.1 2.7 3 0 0 3 3 3 2 Thi4 family FAD_binding_2 PF00890.24 GBG71583.1 - 0.00067 18.8 0.0 0.0023 17.1 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 GBG71583.1 - 0.0018 18.3 0.1 0.5 10.3 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GBG71583.1 - 0.0067 17.0 0.0 2.2 8.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GBG71583.1 - 0.0099 14.8 0.1 0.072 11.9 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase XdhC_C PF13478.6 GBG71583.1 - 0.02 15.4 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 GBG71583.1 - 0.021 14.1 0.3 2.9 7.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GBG71583.1 - 0.032 13.6 0.4 0.3 10.4 0.5 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GBG71583.1 - 0.036 14.3 0.1 0.13 12.5 0.0 2.0 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GBG71583.1 - 0.13 11.0 0.5 0.75 8.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 GBG71583.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 GBG71583.1 - 0.21 10.6 0.0 20 4.1 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A DFP PF04127.15 GBG71584.1 - 2.6e-06 27.4 0.0 4.9e-06 26.5 0.0 1.4 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein DFP PF04127.15 GBG71585.1 - 1.4e-07 31.5 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Cupin_1 PF00190.22 GBG71586.1 - 9.2e-39 132.5 0.1 1.3e-21 76.8 0.3 3.2 3 0 0 3 3 3 2 Cupin Zip PF02535.22 GBG71586.1 - 0.013 14.7 2.4 0.019 14.2 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-C_C PF11699.8 GBG71586.1 - 0.078 13.2 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Mif2/CENP-C like Presenilin PF01080.17 GBG71586.1 - 4.5 5.9 4.1 15 4.2 2.9 1.9 2 0 0 2 2 2 0 Presenilin Cupin_1 PF00190.22 GBG71587.1 - 3.1e-40 137.3 0.1 4.9e-23 81.4 0.5 3.2 3 0 0 3 3 3 2 Cupin Zip PF02535.22 GBG71587.1 - 0.011 14.9 2.2 0.016 14.4 2.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Cupin_1 PF00190.22 GBG71589.1 - 2.2e-38 131.2 0.0 4.1e-22 78.4 0.1 3.0 3 0 0 3 3 3 2 Cupin Zip PF02535.22 GBG71589.1 - 0.11 11.7 1.3 0.15 11.2 1.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GBG71591.1 - 0.07 11.9 11.4 0.091 11.5 11.4 1.1 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.13 GBG71591.1 - 0.18 10.4 14.5 0.23 10.0 14.5 1.1 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 GBG71591.1 - 2.8 6.9 11.0 4.2 6.3 11.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 MAPEG PF01124.18 GBG71592.1 - 0.12 12.3 0.1 0.4 10.6 0.1 1.9 1 0 0 1 1 1 0 MAPEG family RT_RNaseH_2 PF17919.1 GBG71593.1 - 2.7e-27 94.7 0.0 5.9e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71593.1 - 4.1e-26 91.9 0.1 6.2e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71593.1 - 2.7e-23 82.3 0.0 7e-23 80.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG71593.1 - 0.14 11.6 8.6 0.19 11.1 8.6 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG71593.1 - 0.16 10.1 9.9 0.21 9.8 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG71593.1 - 0.72 8.1 11.1 1 7.5 11.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG71593.1 - 1.5 8.3 5.5 2.3 7.7 5.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Atg14 PF10186.9 GBG71594.1 - 0.0076 15.4 9.2 0.013 14.6 9.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 GBG71594.1 - 0.16 12.0 10.2 0.046 13.7 1.4 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding WDCP PF15390.6 GBG71594.1 - 0.32 9.3 8.2 0.45 8.8 8.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family TSC22 PF01166.18 GBG71594.1 - 2.2 8.6 4.8 12 6.2 0.1 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family IFT57 PF10498.9 GBG71594.1 - 9.5 5.1 24.0 0.33 9.9 14.3 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DSPc PF00782.20 GBG71595.1 - 2.6e-19 69.4 0.0 4.4e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GBG71595.1 - 0.0017 18.5 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 GBG71595.1 - 0.0059 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 GBG71595.1 - 0.058 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain PFK PF00365.20 GBG71596.1 - 9.1e-62 208.9 0.5 1.4e-61 208.3 0.5 1.2 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 GBG71596.1 - 0.0029 17.2 0.5 0.01 15.5 0.5 1.9 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF659 PF04937.15 GBG71597.1 - 5.5e-33 114.0 0.1 8.8e-33 113.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cu_bind_like PF02298.17 GBG71598.1 - 0.00075 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Plastocyanin-like domain DnaJ_CXXCXGXG PF00684.19 GBG71599.1 - 0.0072 16.7 7.5 0.019 15.3 7.5 1.7 1 0 0 1 1 1 1 DnaJ central domain zf-Dof PF02701.15 GBG71599.1 - 0.041 14.0 1.2 13 6.0 0.1 3.0 3 0 0 3 3 3 0 Dof domain, zinc finger Anti-TRAP PF15777.5 GBG71599.1 - 0.085 12.8 1.1 0.28 11.2 1.1 1.8 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein BUD22 PF09073.10 GBG71600.1 - 6e-05 22.6 71.9 9.6e-05 21.9 71.9 1.2 1 0 0 1 1 1 1 BUD22 Ribosomal_60s PF00428.19 GBG71600.1 - 0.017 15.7 22.1 0.017 15.7 22.1 6.0 1 1 3 4 4 4 0 60s Acidic ribosomal protein GHMP_kinases_N PF00288.26 GBG71600.1 - 0.055 13.7 0.0 0.092 13.0 0.0 1.3 1 0 0 1 1 1 0 GHMP kinases N terminal domain DUF4710 PF15828.5 GBG71600.1 - 0.4 10.8 0.1 0.4 10.8 0.1 4.8 3 2 0 3 3 3 0 Domain of unknown function (DUF4710) AhpC-TSA_2 PF13911.6 GBG71601.1 - 8.8e-15 54.8 0.1 1.8e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 GBG71601.1 - 1.1e-08 35.1 0.0 2.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GBG71601.1 - 0.0017 18.0 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Redoxin RVT_1 PF00078.27 GBG71601.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71602.1 - 8.5e-34 115.6 0.0 1.6e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71602.1 - 3.2e-29 101.3 0.0 6.3e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71602.1 - 3.2e-19 68.8 0.1 7e-19 67.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71602.1 - 6.3e-16 58.6 0.1 3e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG71602.1 - 0.14 12.4 1.6 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 H2C2 zinc finger Zein-binding PF04576.15 GBG71603.1 - 7.9e-30 103.0 25.3 4.7e-15 55.7 9.3 2.8 2 0 0 2 2 2 2 Zein-binding DUF937 PF06078.11 GBG71603.1 - 0.062 13.9 3.4 1.1 9.8 0.2 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF937) G-gamma PF00631.22 GBG71603.1 - 1.1 9.3 3.3 34 4.5 0.4 2.9 2 1 0 2 2 2 0 GGL domain RT_RNaseH_2 PF17919.1 GBG71604.1 - 1.8e-32 111.3 0.1 3.5e-32 110.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71604.1 - 4e-29 101.7 0.1 6.8e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71604.1 - 2.5e-28 98.4 0.2 4.9e-28 97.5 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ABC_membrane PF00664.23 GBG71606.1 - 6.7e-08 32.5 0.3 9e-08 32.1 0.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region zf-CCHC PF00098.23 GBG71607.1 - 1.9e-05 24.5 3.2 3.5e-05 23.7 3.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG71607.1 - 0.0047 16.7 0.9 0.0047 16.7 0.9 2.1 2 0 0 2 2 2 1 Zinc knuckle AT_hook PF02178.19 GBG71607.1 - 0.018 14.9 1.2 0.018 14.9 1.2 3.4 2 0 0 2 2 2 0 AT hook motif zf-CCHC_4 PF14392.6 GBG71607.1 - 0.11 12.2 0.5 0.22 11.3 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle XRN_M PF17846.1 GBG71607.1 - 0.41 9.6 5.4 0.66 8.9 5.4 1.4 1 0 0 1 1 1 0 Xrn1 helical domain ANAPC15 PF15243.6 GBG71607.1 - 0.89 10.0 10.6 0.49 10.8 1.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 SOBP PF15279.6 GBG71607.1 - 2.4 8.7 6.3 3.5 8.2 6.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Kinesin PF00225.23 GBG71609.1 - 6.9e-108 360.5 2.7 1.2e-107 359.8 2.7 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG71609.1 - 1.1e-25 90.3 0.1 3e-25 88.9 0.1 1.8 1 0 0 1 1 1 1 Microtubule binding TPR_MLP1_2 PF07926.12 GBG71609.1 - 0.00036 20.6 6.3 0.00036 20.6 6.3 4.8 4 1 0 5 5 5 1 TPR/MLP1/MLP2-like protein ComC PF03047.14 GBG71609.1 - 0.062 13.1 0.2 6.3 6.7 0.0 2.6 2 0 0 2 2 2 0 COMC family ATG16 PF08614.11 GBG71609.1 - 0.51 10.5 43.5 0.016 15.4 13.8 4.9 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Tmemb_cc2 PF10267.9 GBG71609.1 - 1.6 7.8 30.1 2.5 7.2 6.9 4.2 3 1 1 4 4 4 0 Predicted transmembrane and coiled-coil 2 protein Lectin_N PF03954.14 GBG71609.1 - 4.6 7.0 6.2 1.1 9.0 0.2 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain gag-asp_proteas PF13975.6 GBG71610.1 - 1.7e-07 31.7 0.0 3.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71610.1 - 6.2e-06 26.8 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71610.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG71612.1 - 6.1e-15 55.1 0.1 1.7e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG71612.1 - 0.015 15.5 0.0 0.048 13.9 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG71614.1 - 5e-09 36.6 0.0 1.1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71614.1 - 2.4e-06 28.1 0.0 5.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71614.1 - 0.00011 22.0 0.8 0.00018 21.3 0.8 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG71614.1 - 0.0016 18.7 0.0 0.0061 16.8 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease GRIM-19 PF06212.12 GBG71615.1 - 1.2e-39 135.3 0.0 1.4e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein DUF2681 PF10883.8 GBG71615.1 - 0.032 14.6 0.6 0.043 14.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Integrase_H2C2 PF17921.1 GBG71617.1 - 5e-15 55.3 0.1 1e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71617.1 - 5.5e-05 23.3 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71617.1 - 0.00067 19.8 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG71619.1 - 2.3e-09 37.7 0.1 6.7e-09 36.2 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71619.1 - 4.6e-08 33.6 0.1 1.1e-07 32.3 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease CCDC-167 PF15188.6 GBG71619.1 - 0.0077 16.6 2.0 0.0077 16.6 2.0 3.8 4 0 0 4 4 4 1 Coiled-coil domain-containing protein 167 Asp_protease PF09668.10 GBG71619.1 - 0.05 13.4 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease RPW8 PF05659.11 GBG71619.1 - 0.1 12.3 3.3 2.5 7.8 0.5 3.3 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 zf-FCS PF06467.14 GBG71619.1 - 0.13 12.2 0.4 0.43 10.6 0.4 1.8 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif USP8_interact PF08941.10 GBG71619.1 - 0.31 10.8 7.2 0.6 9.9 3.9 2.5 2 0 0 2 2 2 0 USP8 interacting Sec8_exocyst PF04048.14 GBG71619.1 - 0.37 10.7 3.2 0.55 10.1 1.6 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 GBG71619.1 - 5.4 7.1 7.6 4.1 7.5 4.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) YTH PF04146.15 GBG71620.1 - 4.6e-47 160.1 2.1 4.7e-47 160.0 0.1 2.0 2 1 0 2 2 2 1 YT521-B-like domain tRNA-synt_2b PF00587.25 GBG71621.1 - 2.7e-37 128.5 0.0 5e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GBG71621.1 - 1.3e-20 73.4 0.3 3.7e-20 71.9 0.3 1.9 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 GBG71621.1 - 4.1e-16 58.8 0.0 7.8e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 GBG71621.1 - 7.4e-11 42.0 0.0 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RVT_1 PF00078.27 GBG71623.1 - 6.6e-26 91.2 0.0 1.4e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71623.1 - 3.1e-11 43.2 0.0 8.9e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG71623.1 - 1.1e-06 29.1 0.0 3.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71623.1 - 2.8e-06 27.9 0.0 6.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG71623.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71623.1 - 0.00071 19.4 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG71623.1 - 0.019 15.2 0.0 0.069 13.4 0.0 2.1 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG71623.1 - 0.023 15.0 0.7 0.19 12.0 0.2 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein Med26_M PF15694.5 GBG71623.1 - 0.63 10.0 3.7 1.3 9.0 3.7 1.6 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain DUF4407 PF14362.6 GBG71623.1 - 1.8 7.8 11.9 3.1 7.1 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pectinesterase PF01095.19 GBG71624.1 - 2.4e-58 197.2 0.0 3.3e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Pectinesterase Fasciclin PF02469.22 GBG71624.1 - 3.8e-14 53.0 0.0 5.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Retrotrans_gag PF03732.17 GBG71625.1 - 2.4e-05 24.5 0.2 0.0019 18.5 0.0 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG71625.1 - 0.01 15.7 0.9 0.021 14.7 0.1 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain AP1AR PF15745.5 GBG71625.1 - 0.016 14.9 4.2 0.025 14.2 4.2 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein AIF-MLS PF14962.6 GBG71625.1 - 0.13 12.2 5.7 0.23 11.4 5.7 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence RT_RNaseH_2 PF17919.1 GBG71626.1 - 3.3e-23 81.6 0.0 6.3e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71626.1 - 1.6e-19 70.1 0.0 4.1e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG71627.1 - 2.9e-31 108.4 0.1 4.8e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71627.1 - 0.0015 18.2 0.3 0.0045 16.8 0.3 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCCH PF00642.24 GBG71629.1 - 1.4e-40 136.4 50.5 4e-10 39.3 2.8 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG71629.1 - 1.7e-17 62.8 62.2 8.9e-07 28.8 5.0 5.4 5 0 0 5 5 5 5 Zinc finger domain zf-CCCH_4 PF18044.1 GBG71629.1 - 1.7e-16 59.5 52.4 5e-05 23.0 2.5 5.3 5 0 0 5 5 5 5 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GBG71629.1 - 1e-08 35.3 48.1 0.0014 19.0 2.5 5.5 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GBG71629.1 - 6.3e-07 30.1 29.5 0.17 12.6 0.6 6.0 5 1 1 6 6 6 4 Torus domain DUF2722 PF10846.8 GBG71629.1 - 0.0038 16.2 1.2 0.0038 16.2 1.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 GBG71629.1 - 0.15 11.6 32.0 0.027 14.1 9.1 3.1 3 0 0 3 3 3 0 Spt20 family DUF3402 PF11882.8 GBG71629.1 - 2.9 6.9 5.5 0.36 9.9 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) TFIIA PF03153.13 GBG71629.1 - 9.6 6.1 32.7 0.025 14.6 3.7 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit N6_N4_Mtase PF01555.18 GBG71630.1 - 0.00013 21.8 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 DNA methylase DUF2052 PF09747.9 GBG71630.1 - 0.023 14.8 9.7 0.13 12.3 10.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 GBG71630.1 - 0.061 12.7 11.4 0.093 12.1 11.4 1.2 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 GBG71630.1 - 0.071 12.5 12.7 0.12 11.8 12.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cnd2 PF05786.14 GBG71630.1 - 0.082 11.6 4.0 0.11 11.2 4.0 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 FAM176 PF14851.6 GBG71630.1 - 0.1 12.2 6.5 0.26 11.0 6.5 1.6 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 GBG71630.1 - 0.28 11.0 9.2 0.48 10.3 9.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Mpp10 PF04006.12 GBG71630.1 - 0.32 9.4 12.7 0.45 8.9 12.7 1.1 1 0 0 1 1 1 0 Mpp10 protein RPN2_C PF18004.1 GBG71630.1 - 0.34 10.8 5.6 0.59 10.0 5.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Paf1 PF03985.13 GBG71630.1 - 0.42 9.6 14.8 0.63 9.0 14.8 1.2 1 0 0 1 1 1 0 Paf1 CPSF100_C PF13299.6 GBG71630.1 - 0.43 10.7 2.6 0.73 10.0 2.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 GBG71630.1 - 0.51 8.5 15.1 0.7 8.0 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG71630.1 - 1.3 7.0 20.2 1.9 6.5 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi MCM_bind PF09739.9 GBG71630.1 - 4.8 5.5 5.0 1.9 6.9 2.2 1.6 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor RRN3 PF05327.11 GBG71630.1 - 5.5 5.4 10.0 7.4 5.0 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GBG71630.1 - 6.1 5.0 15.3 8.7 4.5 15.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG71630.1 - 9.1 5.6 10.7 20 4.5 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TraB PF01963.17 GBG71632.1 - 7.4e-22 78.5 2.4 4.5e-21 75.9 2.4 2.1 1 1 0 1 1 1 1 TraB family GxGYxYP_C PF14323.6 GBG71632.1 - 0.033 14.1 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain RVT_1 PF00078.27 GBG71633.1 - 6.9e-25 87.9 0.1 1e-24 87.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG71633.1 - 3.6e-07 30.4 0.0 8.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG71634.1 - 1.2e-28 100.2 0.1 1.8e-28 99.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71634.1 - 1.6e-27 95.5 0.0 6.2e-27 93.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71634.1 - 5e-24 84.6 0.0 1.5e-23 83.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG71634.1 - 3.3e-06 27.7 0.0 7.8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71634.1 - 2.5e-05 24.7 0.0 5.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG71634.1 - 4.8e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG71634.1 - 0.0066 16.7 0.0 0.043 14.1 0.0 2.4 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG71634.1 - 0.009 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease ABC_membrane PF00664.23 GBG71635.1 - 1.3e-74 251.4 30.5 7.8e-38 130.7 14.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GBG71635.1 - 2.2e-47 161.0 0.2 1.2e-25 90.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GBG71635.1 - 4.5e-09 36.1 0.0 0.011 15.2 0.4 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GBG71635.1 - 0.00019 21.4 0.9 0.088 12.7 0.0 3.2 2 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GBG71635.1 - 0.00022 21.3 0.0 0.15 12.2 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GBG71635.1 - 0.00061 20.2 0.1 0.14 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GBG71635.1 - 0.0028 17.4 1.1 0.36 10.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 GBG71635.1 - 0.0094 16.0 0.4 0.08 13.0 0.5 2.3 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 GBG71635.1 - 0.01 15.5 0.1 5.8 6.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GBG71635.1 - 0.016 15.1 0.2 2.8 7.7 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GBG71635.1 - 0.022 15.0 1.9 2 8.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 GBG71635.1 - 0.028 14.3 0.0 0.9 9.4 0.0 2.8 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 GBG71635.1 - 0.034 13.9 0.6 4.5 6.9 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain DUF815 PF05673.13 GBG71635.1 - 0.058 12.6 0.4 1.2 8.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GBG71635.1 - 0.1 13.0 0.1 4.3 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 GBG71635.1 - 0.11 12.0 0.4 4.7 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 GBG71635.1 - 0.11 13.0 4.8 1.4 9.4 0.1 2.9 3 0 0 3 3 2 0 AAA domain ABC_membrane PF00664.23 GBG71636.1 - 9.5e-73 245.2 25.2 1.3e-36 126.7 8.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GBG71636.1 - 2.2e-47 161.0 0.2 1.2e-25 90.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GBG71636.1 - 4.1e-09 36.2 0.0 0.011 15.2 0.4 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GBG71636.1 - 0.00024 21.1 0.0 0.15 12.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GBG71636.1 - 0.00061 20.2 0.1 0.14 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GBG71636.1 - 0.00064 19.7 2.9 0.087 12.7 0.0 3.4 3 1 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 GBG71636.1 - 0.0036 17.0 1.4 0.38 10.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 GBG71636.1 - 0.0057 17.2 0.4 1.4 9.4 0.1 2.9 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 GBG71636.1 - 0.0098 16.0 0.4 0.082 13.0 0.5 2.3 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 GBG71636.1 - 0.011 15.3 0.1 5.9 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 GBG71636.1 - 0.017 14.9 0.3 2.8 7.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GBG71636.1 - 0.023 15.0 2.0 2.1 8.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 GBG71636.1 - 0.033 13.9 0.0 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 GBG71636.1 - 0.037 13.9 0.0 0.92 9.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 GBG71636.1 - 0.059 12.5 0.4 1.2 8.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 GBG71636.1 - 0.11 12.3 0.3 8.3 6.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 GBG71636.1 - 0.11 12.0 0.4 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GBG71636.1 - 0.12 12.8 0.1 4.4 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase 7tm_1 PF00001.21 GBG71636.1 - 4 6.7 8.0 0.4 10.0 0.2 2.9 2 2 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) Filament PF00038.21 GBG71638.1 - 0.032 13.8 6.7 0.057 13.0 6.7 1.4 1 0 0 1 1 1 0 Intermediate filament protein Prp19 PF08606.11 GBG71638.1 - 0.045 13.7 7.5 1 9.4 5.0 2.8 2 1 0 2 2 2 0 Prp19/Pso4-like YlqD PF11068.8 GBG71638.1 - 0.31 11.4 7.5 0.13 12.6 3.8 2.0 2 0 0 2 2 2 0 YlqD protein DUF745 PF05335.13 GBG71638.1 - 0.91 9.2 7.0 16 5.1 7.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TolA_bind_tri PF16331.5 GBG71638.1 - 3.4 7.8 10.0 11 6.2 5.7 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation FUSC PF04632.12 GBG71638.1 - 6.9 5.1 10.1 9.5 4.6 10.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-CCHC PF00098.23 GBG71639.1 - 9.8e-06 25.4 3.8 1.4e-05 24.9 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle Queuosine_synth PF02547.15 GBG71639.1 - 0.0097 15.1 2.0 0.013 14.7 2.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein Eaf7 PF07904.13 GBG71639.1 - 3.2 8.2 8.3 3.9 7.9 6.9 2.0 1 1 1 2 2 2 0 Chromatin modification-related protein EAF7 YolD PF08863.10 GBG71639.1 - 4.6 7.4 12.0 0.12 12.4 3.8 2.5 3 0 0 3 3 3 0 YolD-like protein RT_RNaseH_2 PF17919.1 GBG71640.1 - 4.5e-76 251.2 0.1 1.4e-36 124.5 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71640.1 - 1.7e-63 211.4 0.0 3.1e-30 104.6 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71640.1 - 1.4e-07 31.3 0.1 4e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HoxA13_N PF12284.8 GBG71640.1 - 0.04 14.5 0.8 15 6.2 0.1 2.4 2 0 0 2 2 2 0 Hox protein A13 N terminal DrrA_P4M PF14860.6 GBG71640.1 - 0.089 12.7 0.0 19 5.2 0.0 2.3 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain AP1AR PF15745.5 GBG71641.1 - 0.0031 17.2 14.8 0.0054 16.4 14.8 1.3 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein Borrelia_P83 PF05262.11 GBG71641.1 - 1.8 7.0 14.0 2 6.8 14.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2229 PF09989.9 GBG71641.1 - 2.6 7.7 8.4 4.5 6.9 8.4 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) CDRT4 PF15213.6 GBG71641.1 - 7.4 7.2 8.5 20 5.8 8.5 1.7 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein XK-related PF09815.9 GBG71642.1 - 0.0047 16.0 3.1 0.0069 15.5 3.1 1.1 1 0 0 1 1 1 1 XK-related protein WBS28 PF15164.6 GBG71642.1 - 0.064 12.5 0.5 0.34 10.1 0.1 2.0 2 0 0 2 2 2 0 Williams-Beuren syndrome chromosomal region 28 protein homologue DNA_pol_phi PF04931.13 GBG71643.1 - 2.5 6.1 7.4 3.6 5.6 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 GBG71643.1 - 5.5 6.0 7.4 8.2 5.5 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAPP PF04051.16 GBG71644.1 - 1.3e-36 125.5 0.1 1.6e-36 125.3 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Josephin PF02099.17 GBG71645.1 - 0.00023 21.3 0.0 0.0013 18.9 0.0 2.1 2 0 0 2 2 2 1 Josephin AT_hook PF02178.19 GBG71647.1 - 0.00021 20.8 12.8 0.14 12.1 2.6 3.7 2 0 0 2 2 2 2 AT hook motif SR-25 PF10500.9 GBG71647.1 - 0.11 12.1 34.5 0.96 9.0 13.0 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FAM60A PF15396.6 GBG71647.1 - 0.32 11.0 18.2 0.67 9.9 3.8 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Mitofilin PF09731.9 GBG71647.1 - 4.3 6.1 24.0 2.7 6.7 8.0 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DUF755 PF05501.11 GBG71647.1 - 4.7 7.5 32.4 9.3 6.5 12.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) CDC27 PF09507.10 GBG71647.1 - 4.7 6.5 53.9 4.9 6.4 22.9 2.1 1 1 1 2 2 2 0 DNA polymerase subunit Cdc27 Phasin PF05597.11 GBG71647.1 - 5.9 6.9 18.0 9.1 6.3 5.0 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4615 PF15393.6 GBG71647.1 - 8.5 6.9 15.7 14 6.3 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) Hc1 PF07432.13 GBG71647.1 - 9 6.7 41.2 12 6.2 16.6 2.3 2 0 0 2 2 2 0 Histone H1-like protein Hc1 cNMP_binding PF00027.29 GBG71648.1 - 1.8e-38 130.5 0.1 1.4e-18 66.7 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 GBG71648.1 - 1.2e-12 47.8 0.0 1.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71648.1 - 0.0011 18.3 0.1 0.0017 17.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG71649.1 - 2e-35 122.5 0.0 3.5e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG71649.1 - 1.6e-15 56.9 0.0 4e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71649.1 - 6e-14 52.1 0.0 1.4e-13 50.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG71649.1 - 5.8e-13 48.7 0.0 9.9e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RT_RNaseH PF17917.1 GBG71649.1 - 1.7e-08 34.7 0.0 1.4e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG71649.1 - 3.1e-05 24.5 0.2 0.00015 22.3 0.0 2.2 3 0 0 3 3 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71649.1 - 3.9e-05 24.2 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Kinase-like PF14531.6 GBG71649.1 - 0.00025 20.5 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Retrotrans_gag PF03732.17 GBG71649.1 - 0.00093 19.4 4.5 0.076 13.3 0.1 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG71649.1 - 0.0081 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease FlxA PF14282.6 GBG71649.1 - 0.024 14.6 1.0 0.024 14.6 1.0 2.0 2 0 0 2 2 2 0 FlxA-like protein APG17 PF04108.12 GBG71649.1 - 0.037 13.2 0.1 0.36 9.9 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 Vfa1 PF08432.10 GBG71649.1 - 0.12 12.7 1.2 0.21 11.9 1.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pkinase PF00069.25 GBG71650.1 - 6.1e-20 71.7 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG71650.1 - 8.5e-17 61.0 0.0 2.2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71650.1 - 7.8e-14 51.7 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71650.1 - 1.1e-09 38.4 0.0 7.8e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Pkinase_Tyr PF07714.17 GBG71650.1 - 1e-05 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase gag-asp_proteas PF13975.6 GBG71650.1 - 4.2e-05 24.0 0.1 0.00018 22.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71650.1 - 5e-05 23.9 0.0 0.00014 22.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG71650.1 - 0.0017 18.6 4.5 0.094 13.0 0.1 3.7 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG71650.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease APG17 PF04108.12 GBG71650.1 - 0.055 12.6 0.1 0.44 9.6 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 Chromo PF00385.24 GBG71650.1 - 0.064 13.2 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Vfa1 PF08432.10 GBG71650.1 - 0.14 12.5 1.2 0.26 11.6 1.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FlxA PF14282.6 GBG71650.1 - 0.2 11.7 5.4 0.029 14.4 1.0 1.9 2 0 0 2 2 1 0 FlxA-like protein NOP5NT PF08156.13 GBG71652.1 - 0.03 14.7 3.1 1.4e+02 3.0 0.0 5.8 5 0 0 5 5 5 0 NOP5NT (NUC127) domain GLTT PF01744.20 GBG71653.1 - 0.0007 19.3 0.1 0.2 11.5 0.1 3.0 1 1 1 2 2 2 2 GLTT repeat (6 copies) DUF5582 PF17819.1 GBG71654.1 - 4e-06 27.3 0.0 6.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5582) EF-hand_6 PF13405.6 GBG71654.1 - 0.038 13.9 0.7 0.23 11.5 0.0 2.7 5 0 0 5 5 5 0 EF-hand domain EF-hand_7 PF13499.6 GBG71654.1 - 0.15 12.5 0.0 9 6.8 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain pair F5_F8_type_C PF00754.25 GBG71655.1 - 0.0028 17.8 0.0 0.0049 17.0 0.0 1.3 1 1 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 GBG71655.1 - 0.004 16.8 0.0 0.0074 15.9 0.0 1.4 2 0 0 2 2 2 1 Anaphase-promoting complex, subunit 10 (APC10) Spidroin_N PF16763.5 GBG71655.1 - 0.0055 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term XRCC1_N PF01834.16 GBG71655.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 XRCC1 N terminal domain UBD PF16455.5 GBG71656.1 - 2e-32 111.5 0.0 2.3e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-binding domain Trehalose_PPase PF02358.16 GBG71657.1 - 0.17 11.0 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Trehalose-phosphatase DUF3143 PF11341.8 GBG71658.1 - 8e-21 74.2 0.0 1.3e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3143) RVT_1 PF00078.27 GBG71660.1 - 7.5e-17 61.6 0.0 1.5e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71660.1 - 3e-09 36.8 0.0 7.6e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71660.1 - 0.024 14.9 0.0 0.081 13.2 0.0 2.0 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Fez1 PF06818.15 GBG71660.1 - 0.029 14.8 0.0 0.029 14.8 0.0 2.7 3 0 0 3 3 3 0 Fez1 Retrotrans_gag PF03732.17 GBG71662.1 - 0.0075 16.5 0.1 0.0075 16.5 0.1 2.7 4 0 0 4 4 4 1 Retrotransposon gag protein Fez1 PF06818.15 GBG71662.1 - 0.025 15.0 0.0 0.025 15.0 0.0 2.4 2 0 0 2 2 2 0 Fez1 DUF1664 PF07889.12 GBG71662.1 - 0.25 11.4 2.0 1.4 9.0 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 GBG71662.1 - 1.3 9.5 6.6 17 6.0 0.0 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4187 PF13821.6 GBG71662.1 - 3.8 7.4 8.0 0.81 9.5 2.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) gag-asp_proteas PF13975.6 GBG71663.1 - 0.00014 22.4 0.0 0.00034 21.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71663.1 - 0.0015 19.1 0.0 0.0034 18.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG71663.1 - 0.0036 17.6 0.0 0.0096 16.2 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG71663.1 - 0.0071 15.9 0.0 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG71663.1 - 0.018 15.3 0.1 0.11 12.8 0.1 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG71663.1 - 0.019 14.8 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_4 PF14392.6 GBG71664.1 - 0.18 11.5 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1840 PF08895.11 GBG71664.1 - 0.32 11.3 17.1 0.03 14.6 10.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) RT_RNaseH_2 PF17919.1 GBG71665.1 - 1.7e-66 220.5 0.0 1.6e-32 111.5 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71665.1 - 2.1e-61 207.3 0.5 2.2e-33 115.7 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71665.1 - 4.9e-60 200.3 0.1 4.6e-30 104.0 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG71665.1 - 1.2e-05 25.1 0.0 3.4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71665.1 - 0.0035 18.0 0.0 0.0072 17.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71665.1 - 0.18 12.4 0.0 0.46 11.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG71665.1 - 0.33 11.3 3.2 0.35 11.2 0.0 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG71666.1 - 2.2e-22 79.0 0.0 3.8e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71666.1 - 2.4e-19 69.5 0.0 5.1e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71666.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG71667.1 - 1.6e-13 50.8 0.0 3.2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Methyltransf_11 PF08241.12 GBG71667.1 - 1.4e-11 44.9 0.0 4.2e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG71667.1 - 1.3e-10 41.9 0.0 4.5e-10 40.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GBG71667.1 - 6.5e-08 32.4 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 GBG71667.1 - 5e-06 26.4 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG71667.1 - 6.1e-06 26.2 0.0 2.3e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GBG71667.1 - 4.3e-05 22.9 1.3 0.00032 20.1 0.0 2.7 3 0 0 3 3 3 1 Mycolic acid cyclopropane synthetase gag-asp_proteas PF13975.6 GBG71667.1 - 0.00039 20.9 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Methyltransf_12 PF08242.12 GBG71667.1 - 0.0011 19.6 0.0 0.0032 18.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Asp_protease PF09668.10 GBG71667.1 - 0.016 15.0 2.8 0.03 14.1 1.8 1.9 2 0 0 2 2 2 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG71667.1 - 0.02 15.6 0.0 0.084 13.5 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.27 GBG71668.1 - 0.019 14.4 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71669.1 - 1.4e-22 79.6 0.0 2.7e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71669.1 - 1.4e-21 76.7 0.0 5.1e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71669.1 - 1.8e-14 53.5 0.1 5.1e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Beach PF02138.18 GBG71670.1 - 5.9e-82 275.1 0.0 8.8e-82 274.6 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain DUF659 PF04937.15 GBG71670.1 - 4.9e-21 75.2 0.0 1.4e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) WD40 PF00400.32 GBG71670.1 - 1.6e-12 47.7 7.5 3.8e-06 27.5 0.4 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Dimer_Tnp_hAT PF05699.14 GBG71670.1 - 5.9e-09 35.6 1.4 1.5e-08 34.3 1.4 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ANAPC4_WD40 PF12894.7 GBG71670.1 - 0.00017 21.8 1.1 0.85 10.0 0.1 4.3 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Beach PF02138.18 GBG71671.1 - 5.6e-82 275.2 0.0 8.4e-82 274.6 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain DUF659 PF04937.15 GBG71671.1 - 4.6e-21 75.3 0.0 1.3e-20 73.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) WD40 PF00400.32 GBG71671.1 - 1.8e-12 47.6 7.5 3.7e-06 27.6 0.4 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Dimer_Tnp_hAT PF05699.14 GBG71671.1 - 5.6e-09 35.7 1.4 1.4e-08 34.4 1.4 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ANAPC4_WD40 PF12894.7 GBG71671.1 - 0.00015 22.0 1.0 0.82 10.0 0.1 4.4 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 GBG71673.1 - 3.9e-56 190.1 0.1 3e-32 111.9 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71673.1 - 3.4e-42 143.0 0.5 1.6e-21 76.5 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71673.1 - 1.6e-33 114.7 0.0 3.6e-22 78.3 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71673.1 - 2.6e-18 65.9 0.0 5.8e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF4800 PF16057.5 GBG71673.1 - 5.1e-10 39.0 0.6 1.5e-09 37.5 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) RVP_2 PF08284.11 GBG71673.1 - 4.6e-06 26.4 0.0 9.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71673.1 - 0.0001 22.8 0.0 0.00023 21.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71673.1 - 0.0037 17.8 0.0 0.013 16.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG71673.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG71673.1 - 0.032 14.5 0.0 0.24 11.7 0.0 2.5 2 0 0 2 2 2 0 H2C2 zinc finger Asp_protease PF09668.10 GBG71673.1 - 0.036 13.9 0.0 0.52 10.1 0.0 2.8 3 0 0 3 3 3 0 Aspartyl protease DUF1088 PF06469.11 GBG71673.1 - 0.075 12.7 0.5 0.2 11.3 0.5 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) DinB PF05163.12 GBG71673.1 - 4.3 7.2 5.4 43 4.0 0.0 3.1 3 0 0 3 3 3 0 DinB family zf-CCHC PF00098.23 GBG71674.1 - 9.7e-07 28.6 2.9 3.3e-06 26.9 2.9 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG71674.1 - 0.053 13.5 1.4 0.13 12.3 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Terminase_3C PF17288.2 GBG71674.1 - 0.057 13.8 2.3 1.9 8.9 3.6 2.3 2 0 0 2 2 2 0 Terminase RNAseH like domain zf-CCHC_2 PF13696.6 GBG71674.1 - 0.13 12.1 1.0 0.29 11.0 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle AP1AR PF15745.5 GBG71674.1 - 0.65 9.6 15.6 1.2 8.7 15.6 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF1682 PF07946.14 GBG71674.1 - 1.4 8.1 20.4 2.1 7.5 20.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SpoVR PF04293.13 GBG71674.1 - 2.7 6.6 9.3 4 6.0 9.3 1.2 1 0 0 1 1 1 0 SpoVR like protein SmAKAP PF15127.6 GBG71674.1 - 6.7 8.0 8.8 30 5.9 8.8 2.1 1 0 0 1 1 1 0 Small membrane A-kinase anchor protein DUF4704 PF15787.5 GBG71675.1 - 4.4e-64 216.4 2.1 9.7e-64 215.3 0.0 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 GBG71675.1 - 9.2e-09 35.6 0.0 2.8e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4703 PF15775.5 GBG71676.1 - 0.021 14.6 0.5 0.083 12.7 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4703) Integrase_H2C2 PF17921.1 GBG71677.1 - 1e-10 41.5 0.1 1.8e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG71677.1 - 2.2e-05 24.7 0.0 0.00083 19.6 0.0 2.3 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71677.1 - 0.00013 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Kinesin PF00225.23 GBG71678.1 - 2.6e-104 348.8 0.4 5.9e-104 347.6 0.4 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG71678.1 - 2.2e-47 160.7 11.0 3.1e-47 160.2 0.1 3.4 3 0 0 3 3 3 1 Microtubule binding MyTH4 PF00784.17 GBG71678.1 - 8.7e-27 93.7 0.0 8.7e-27 93.7 0.0 2.4 3 0 0 3 3 2 1 MyTH4 domain FERM_M PF00373.18 GBG71678.1 - 4.8e-17 62.4 0.0 4.8e-17 62.4 0.0 3.0 2 1 0 2 2 1 1 FERM central domain FERM_N PF09379.10 GBG71678.1 - 1.1e-08 34.8 0.0 2.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain HAP1_N PF04849.13 GBG71678.1 - 0.0006 19.1 11.0 0.0006 19.1 11.0 3.0 2 1 1 3 3 3 1 HAP1 N-terminal conserved region Med21 PF11221.8 GBG71678.1 - 0.0082 16.4 9.8 0.0082 16.4 9.8 5.4 4 1 0 6 6 6 1 Subunit 21 of Mediator complex DUF3426 PF11906.8 GBG71678.1 - 0.0086 16.3 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3426) Mce4_CUP1 PF11887.8 GBG71678.1 - 0.023 14.1 0.9 0.075 12.5 0.9 1.8 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Fez1 PF06818.15 GBG71678.1 - 0.036 14.5 54.9 0.3 11.5 26.6 3.9 2 1 1 3 3 3 0 Fez1 Laminin_II PF06009.12 GBG71678.1 - 0.37 10.8 34.8 0.36 10.8 4.4 3.9 2 1 0 3 3 3 0 Laminin Domain II DUF5395 PF17373.2 GBG71678.1 - 0.43 11.3 2.1 1.6 9.4 0.5 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5395) DUF1664 PF07889.12 GBG71678.1 - 0.7 9.9 28.3 0.61 10.1 4.5 4.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GBG71678.1 - 1.3 9.2 34.4 5.2 7.3 5.5 3.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 GBG71678.1 - 2.5 8.3 51.4 0.79 10.0 10.7 4.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 GBG71678.1 - 2.6 8.1 58.5 0.092 12.8 8.9 4.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Kinesin PF00225.23 GBG71679.1 - 2.4e-104 348.8 0.4 5.7e-104 347.6 0.4 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG71679.1 - 2.1e-47 160.8 11.0 3.1e-47 160.3 0.1 3.5 3 0 0 3 3 3 1 Microtubule binding MyTH4 PF00784.17 GBG71679.1 - 8.5e-27 93.8 0.0 8.5e-27 93.8 0.0 2.4 3 0 0 3 3 2 1 MyTH4 domain FERM_M PF00373.18 GBG71679.1 - 4.7e-17 62.5 0.0 4.7e-17 62.5 0.0 3.1 2 1 0 2 2 1 1 FERM central domain FERM_N PF09379.10 GBG71679.1 - 1.1e-08 34.9 0.0 2.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain HAP1_N PF04849.13 GBG71679.1 - 0.00058 19.2 11.0 0.00058 19.2 11.0 3.0 2 1 0 2 2 1 1 HAP1 N-terminal conserved region Med21 PF11221.8 GBG71679.1 - 0.0079 16.4 9.8 0.0079 16.4 9.8 5.4 4 1 0 6 6 6 1 Subunit 21 of Mediator complex DUF3426 PF11906.8 GBG71679.1 - 0.0082 16.3 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3426) Mce4_CUP1 PF11887.8 GBG71679.1 - 0.022 14.2 0.9 0.073 12.5 0.9 1.8 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Fez1 PF06818.15 GBG71679.1 - 0.033 14.7 54.9 0.29 11.5 26.6 3.9 2 1 1 3 3 3 0 Fez1 Laminin_II PF06009.12 GBG71679.1 - 0.34 10.9 34.8 0.35 10.9 4.4 3.9 2 1 0 3 3 3 0 Laminin Domain II DUF5395 PF17373.2 GBG71679.1 - 0.4 11.3 2.1 1.6 9.5 0.5 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5395) DUF1664 PF07889.12 GBG71679.1 - 0.65 10.0 28.3 0.6 10.2 4.5 4.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GBG71679.1 - 1.2 9.3 34.4 5 7.3 5.5 3.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 GBG71679.1 - 2.3 8.5 51.4 0.77 10.0 10.7 4.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 GBG71679.1 - 2.3 8.3 58.5 0.09 12.9 8.9 4.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 GBG71679.1 - 9.4 5.0 58.7 1.3 7.8 11.2 3.6 3 1 0 3 3 3 0 Spc7 kinetochore protein RVT_1 PF00078.27 GBG71681.1 - 2.1e-29 102.6 0.2 3.5e-29 101.9 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71681.1 - 9.5e-29 99.4 0.0 6.4e-15 55.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71681.1 - 3.5e-28 98.0 0.0 7.6e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71681.1 - 1.1e-14 54.2 0.1 1.1e-14 54.2 0.1 2.1 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG71681.1 - 8.4e-06 26.0 0.0 2.6e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71681.1 - 0.0013 18.8 0.2 0.0042 17.3 0.2 1.9 1 0 0 1 1 1 1 H2C2 zinc finger IDO PF01231.18 GBG71682.1 - 3.2e-06 26.2 0.0 8.3e-05 21.5 0.0 2.3 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase zf-CCHC PF00098.23 GBG71683.1 - 0.085 13.0 2.2 0.18 12.0 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG71683.1 - 0.14 12.0 0.6 0.26 11.1 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle YcbB PF08664.10 GBG71683.1 - 1.1 9.4 6.1 0.46 10.5 3.7 1.6 1 1 1 2 2 2 0 YcbB domain DUF3143 PF11341.8 GBG71684.1 - 0.011 16.1 0.1 0.04 14.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) FlpD PF02662.16 GBG71684.1 - 0.4 10.7 2.6 9.2 6.3 0.1 2.6 3 0 0 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit zf-CCCH PF00642.24 GBG71685.1 - 2.3e-10 40.1 19.3 3.3e-07 30.1 3.0 3.3 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 GBG71685.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 GBG71685.1 - 0.0086 16.1 2.3 0.0086 16.1 2.3 3.3 4 0 0 4 4 4 2 Zinc finger domain DUF3549 PF12069.8 GBG71685.1 - 0.036 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Torus PF16131.5 GBG71685.1 - 0.048 14.4 0.2 0.048 14.4 0.2 2.8 3 0 0 3 3 3 0 Torus domain KxDL PF10241.9 GBG71686.1 - 0.0046 17.2 0.3 0.41 10.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein SlyX PF04102.12 GBG71687.1 - 0.022 15.4 0.2 0.11 13.1 0.0 2.2 2 0 0 2 2 2 0 SlyX Mpp10 PF04006.12 GBG71688.1 - 0.38 9.1 39.2 0.41 9.0 39.2 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC27 PF09507.10 GBG71688.1 - 0.98 8.7 39.0 1.1 8.6 39.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 GBG71688.1 - 1.5 7.0 36.6 1.7 6.9 36.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4589 PF15252.6 GBG71688.1 - 3.3 7.7 15.8 4.9 7.1 15.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Nop14 PF04147.12 GBG71688.1 - 4.4 5.4 39.5 4.7 5.3 39.5 1.0 1 0 0 1 1 1 0 Nop14-like family eIF3_subunit PF08597.10 GBG71688.1 - 5.4 6.8 42.2 7.1 6.5 42.2 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Nop53 PF07767.11 GBG71688.1 - 6.8 6.0 43.6 8.4 5.7 43.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.12 GBG71688.1 - 8.1 5.8 44.3 9.5 5.5 44.3 1.1 1 0 0 1 1 1 0 SDA1 PrmA PF06325.13 GBG71689.1 - 6.2e-12 45.5 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GBG71689.1 - 7e-11 42.7 0.0 1.5e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG71689.1 - 2.8e-10 40.7 0.0 5.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG71689.1 - 7.3e-07 29.1 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG71689.1 - 2.6e-06 27.1 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GBG71689.1 - 1.8e-05 24.6 0.0 3.2e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 GBG71689.1 - 3.5e-05 23.3 0.0 5.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PRMT5 PF05185.16 GBG71689.1 - 6.9e-05 22.8 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 GBG71689.1 - 0.0002 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 GBG71689.1 - 0.00058 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GBG71689.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 GBG71689.1 - 0.0047 15.9 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 GBG71689.1 - 0.0051 17.8 0.1 0.012 16.6 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GBG71689.1 - 0.0074 16.0 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 GBG71689.1 - 0.071 13.9 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3274 PF11678.8 GBG71689.1 - 0.33 10.2 1.8 0.8 8.9 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3274) DUF659 PF04937.15 GBG71690.1 - 7.4e-21 74.6 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) UPF0561 PF10573.9 GBG71690.1 - 0.038 14.1 2.1 0.21 11.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Dimer_Tnp_hAT PF05699.14 GBG71690.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF4672 PF15716.5 GBG71690.1 - 0.17 11.5 0.7 0.35 10.5 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) RVT_1 PF00078.27 GBG71692.1 - 4.2e-18 65.7 0.0 5.8e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Focadhesin PF11229.8 GBG71692.1 - 0.063 11.5 0.0 0.078 11.2 0.0 1.1 1 0 0 1 1 1 0 Focadhesin Laminin_B PF00052.18 GBG71693.1 - 0.0094 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Laminin B (Domain IV) DUF2961 PF11175.8 GBG71693.1 - 0.083 12.5 0.6 0.38 10.4 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2961) zf-C3HC4_3 PF13920.6 GBG71694.1 - 3.1e-11 43.0 12.1 4.6e-11 42.4 12.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG71694.1 - 2.3e-06 27.4 11.5 3.8e-06 26.7 11.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GBG71694.1 - 0.0046 17.3 13.7 0.0086 16.4 13.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG71694.1 - 0.011 15.7 11.5 0.02 14.9 11.5 1.5 1 1 0 1 1 1 0 zinc-RING finger domain RT_RNaseH_2 PF17919.1 GBG71696.1 - 2.5e-33 114.1 0.0 4e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71696.1 - 3.8e-21 75.4 0.0 6.2e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71696.1 - 9.4e-06 25.3 0.1 1.5e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DRMBL PF07522.14 GBG71697.1 - 6.5e-11 42.4 0.0 1.8e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 GBG71697.1 - 4.2e-07 29.7 0.4 8.6e-07 28.7 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Eapp_C PF10238.9 GBG71697.1 - 1.2 9.2 6.3 3.4 7.7 6.3 1.8 1 0 0 1 1 1 0 E2F-associated phosphoprotein RR_TM4-6 PF06459.12 GBG71697.1 - 5.9 6.6 8.3 11 5.7 8.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 GBG71697.1 - 8.9 6.1 13.9 0.056 13.4 5.2 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal GCD14 PF08704.10 GBG71698.1 - 1.3e-88 296.8 0.0 1.6e-87 293.3 0.0 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CoaE PF01121.20 GBG71698.1 - 7.6e-31 107.2 0.0 1.2e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase Methyltransf_31 PF13847.6 GBG71698.1 - 3.3e-09 36.7 0.0 2.7e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 GBG71698.1 - 8.9e-06 25.6 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 GBG71698.1 - 2.9e-05 24.7 0.0 9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 GBG71698.1 - 0.00018 22.5 0.0 0.00042 21.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG71698.1 - 0.0026 18.5 0.0 0.0068 17.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG71698.1 - 0.004 17.8 0.0 0.012 16.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG71698.1 - 0.032 13.8 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 GBG71698.1 - 0.049 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 GBG71698.1 - 0.062 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 GBG71698.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase C2 PF00168.30 GBG71699.1 - 1.7e-13 50.8 0.1 6.9e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 C2 domain PLDc PF00614.22 GBG71699.1 - 2e-11 43.6 0.4 6.7e-06 26.1 0.0 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG71699.1 - 4.7e-11 42.7 0.4 7.7e-07 29.1 0.0 3.7 2 2 1 3 3 3 2 PLD-like domain zf-C3HC4_3 PF13920.6 GBG71701.1 - 9.8e-11 41.3 8.2 2.7e-10 39.9 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG71701.1 - 9.3e-10 38.2 11.7 1.8e-09 37.3 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG71701.1 - 2.7e-08 34.0 11.0 7.3e-08 32.6 11.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG71701.1 - 1.7e-06 27.9 5.4 1.7e-06 27.9 5.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG71701.1 - 2.2e-06 27.5 8.8 5.1e-06 26.3 8.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GBG71701.1 - 7.4e-05 22.8 11.2 0.00019 21.5 11.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GBG71701.1 - 0.00011 22.0 5.5 0.0003 20.6 5.5 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.15 GBG71701.1 - 0.00021 21.4 0.4 0.00092 19.3 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-C3HC4 PF00097.25 GBG71701.1 - 0.00027 20.7 10.4 0.00054 19.8 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 GBG71701.1 - 0.0014 18.3 5.8 0.0041 16.8 5.8 1.8 1 0 0 1 1 1 1 P-11 zinc finger Prok-RING_4 PF14447.6 GBG71701.1 - 0.0018 18.1 9.6 0.005 16.7 9.6 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GBG71701.1 - 0.15 12.4 8.2 0.51 10.7 8.2 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 GBG71701.1 - 0.25 11.1 15.3 0.061 13.1 11.6 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 GBG71701.1 - 0.34 11.1 5.4 0.83 9.8 5.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 GBG71701.1 - 0.4 10.5 7.1 0.82 9.5 7.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ISN1 PF06437.11 GBG71702.1 - 1.3e-94 317.4 0.0 1.8e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Hydrolase_3 PF08282.12 GBG71702.1 - 0.00018 21.3 0.1 0.044 13.5 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Pilt PF15453.6 GBG71702.1 - 1.3 8.4 3.5 2 7.8 3.5 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Ank_2 PF12796.7 GBG71703.1 - 2.9e-40 136.7 0.3 8.1e-19 68.0 0.2 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG71703.1 - 1.9e-24 85.7 3.2 3e-14 53.2 0.9 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG71703.1 - 4.2e-23 78.9 1.4 9.6e-07 28.7 0.0 5.6 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GBG71703.1 - 2.1e-22 78.9 6.2 2.1e-11 43.8 0.8 4.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GBG71703.1 - 4.5e-21 74.3 5.4 3e-06 27.4 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Stomagen PF16851.5 GBG71703.1 - 0.0012 18.9 0.5 0.0041 17.1 0.5 1.9 1 0 0 1 1 1 1 Stomagen RT_RNaseH_2 PF17919.1 GBG71704.1 - 1.3e-26 92.5 0.0 4.9e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71704.1 - 7.3e-23 80.9 0.0 2.2e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71704.1 - 5.6e-20 71.2 0.3 1.3e-19 70.0 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG71704.1 - 3.8e-08 33.9 0.0 1.1e-07 32.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71704.1 - 2.1e-07 31.4 0.0 8.9e-07 29.4 0.0 2.2 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG71704.1 - 8.7e-06 25.5 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG71704.1 - 8.4e-05 22.8 1.5 0.0017 18.6 0.1 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG71704.1 - 0.00017 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG71704.1 - 0.093 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger DUF4407 PF14362.6 GBG71704.1 - 0.096 12.0 10.5 0.92 8.8 6.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RNR_Alpha PF17975.1 GBG71704.1 - 0.13 12.8 0.1 11 6.6 0.0 2.8 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain Senescence_reg PF04520.13 GBG71704.1 - 0.57 11.0 6.8 0.18 12.6 2.7 2.2 2 0 0 2 2 2 0 Senescence regulator SNAPc19 PF15497.6 GBG71704.1 - 1.1 9.8 3.9 1.2 9.7 0.0 2.6 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Ank_2 PF12796.7 GBG71705.1 - 1.2e-24 86.7 0.6 2.2e-13 50.6 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG71705.1 - 5e-21 74.8 1.5 1.6e-07 31.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG71705.1 - 2.4e-20 72.3 1.0 2.2e-07 31.0 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GBG71705.1 - 5.9e-19 67.6 3.0 7.7e-07 29.3 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 GBG71705.1 - 9.7e-14 50.1 0.2 5e-05 23.4 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Glyoxalase_6 PF18029.1 GBG71705.1 - 2.1 9.2 5.4 11 6.9 0.5 2.3 1 1 1 2 2 2 0 Glyoxalase-like domain Annexin PF00191.20 GBG71706.1 - 1.2e-45 153.4 0.2 3.1e-17 62.4 0.0 4.2 4 0 0 4 4 4 3 Annexin DUF968 PF06147.11 GBG71706.1 - 0.00093 19.5 0.0 0.0071 16.6 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF968) TetR_C_15 PF17918.1 GBG71706.1 - 0.012 16.3 0.0 0.061 14.1 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain zf-HC5HC2H_2 PF13832.6 GBG71707.1 - 8.5e-31 106.4 6.6 8.5e-31 106.4 6.6 3.5 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GBG71707.1 - 2.9e-24 85.1 11.9 6.8e-23 80.7 3.1 4.1 3 0 0 3 3 3 2 PHD-like zinc-binding domain PWWP PF00855.17 GBG71707.1 - 1.9e-15 57.0 0.1 7.5e-15 55.1 0.1 2.2 1 0 0 1 1 1 1 PWWP domain FYRN PF05964.14 GBG71707.1 - 1.2e-14 53.8 0.1 2.8e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 GBG71707.1 - 2.2e-13 50.9 1.1 7.8e-13 49.2 0.1 2.6 2 1 0 2 2 2 1 SET domain PHD_2 PF13831.6 GBG71707.1 - 2.2e-12 46.3 2.8 2.2e-12 46.3 2.8 4.5 5 0 0 5 5 4 1 PHD-finger FYRC PF05965.14 GBG71707.1 - 9.6e-10 38.5 0.0 2.6e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus gag-asp_proteas PF13975.6 GBG71707.1 - 1.5e-07 31.8 0.8 3.7e-05 24.2 0.0 3.2 3 0 0 3 3 2 1 gag-polyprotein putative aspartyl protease PHD PF00628.29 GBG71707.1 - 2.2e-07 30.6 6.5 2.2e-07 30.6 6.5 4.7 5 0 0 5 5 5 1 PHD-finger Asp_protease_2 PF13650.6 GBG71707.1 - 4.6e-07 30.4 1.9 0.00041 20.9 0.0 4.0 4 0 0 4 4 4 1 Aspartyl protease C1_1 PF00130.22 GBG71707.1 - 0.0042 16.9 0.5 0.0042 16.9 0.5 4.6 4 1 0 4 4 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RVP PF00077.20 GBG71707.1 - 0.029 14.7 0.3 1.5 9.2 0.0 3.0 3 0 0 3 3 2 0 Retroviral aspartyl protease FYVE_2 PF02318.16 GBG71707.1 - 0.052 13.8 4.3 0.096 12.9 1.7 2.9 2 0 0 2 2 1 0 FYVE-type zinc finger Asp_protease PF09668.10 GBG71707.1 - 0.11 12.3 1.3 0.31 10.8 0.9 1.9 1 1 1 2 2 2 0 Aspartyl protease RT_RNaseH PF17917.1 GBG71709.1 - 7.5e-22 77.6 0.0 4.6e-21 75.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71709.1 - 5.1e-20 71.4 0.0 6e-19 67.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71709.1 - 2.8e-08 33.6 0.0 4.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG71709.1 - 0.13 12.1 0.3 0.22 11.3 0.3 1.3 1 0 0 1 1 1 0 Aspartyl protease LRR_8 PF13855.6 GBG71710.1 - 3.1e-11 42.9 22.9 0.0094 15.7 0.3 4.8 3 1 0 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 GBG71710.1 - 5.6e-06 26.2 12.7 14 6.7 0.0 8.9 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 GBG71710.1 - 2.5e-05 24.0 12.9 0.66 10.2 0.5 6.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 GBG71710.1 - 3e-05 24.3 10.4 0.00032 21.0 3.1 6.9 4 3 2 6 6 6 3 Leucine Rich repeats (2 copies) Lectin_C PF00059.21 GBG71710.1 - 0.0086 16.8 0.4 0.0086 16.8 0.4 3.3 3 1 0 3 3 3 1 Lectin C-type domain cEGF PF12662.7 GBG71710.1 - 0.34 10.9 13.0 0.68 9.9 0.2 4.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like LRR_9 PF14580.6 GBG71710.1 - 0.44 10.0 4.0 4.2 6.8 0.8 2.4 2 0 0 2 2 2 0 Leucine-rich repeat UL45 PF05473.12 GBG71710.1 - 1.9 8.1 5.3 0.96 9.0 1.3 2.3 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like LRR_8 PF13855.6 GBG71711.1 - 4.7e-11 42.3 22.7 0.0094 15.7 0.3 4.8 3 1 0 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 GBG71711.1 - 7.9e-06 25.7 13.1 14 6.7 0.0 8.9 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 GBG71711.1 - 2.4e-05 24.0 13.2 0.66 10.2 0.5 6.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 GBG71711.1 - 3e-05 24.3 10.4 0.00032 21.0 3.1 6.8 4 3 2 6 6 6 3 Leucine Rich repeats (2 copies) Lectin_C PF00059.21 GBG71711.1 - 0.0086 16.8 0.4 0.0086 16.8 0.4 3.3 3 1 0 3 3 3 1 Lectin C-type domain cEGF PF12662.7 GBG71711.1 - 0.48 10.4 13.3 0.82 9.7 0.2 4.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like LRR_9 PF14580.6 GBG71711.1 - 1.8 8.0 5.8 4.2 6.8 0.8 2.3 2 0 0 2 2 2 0 Leucine-rich repeat UL45 PF05473.12 GBG71711.1 - 2.4 7.7 5.6 0.96 9.0 1.3 2.3 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like CS PF04969.16 GBG71712.1 - 3.1e-08 34.5 0.0 4.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 CS domain FPL PF09758.9 GBG71713.1 - 1.4e-54 184.1 1.6 1.4e-54 184.1 1.6 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein FPL PF09758.9 GBG71714.1 - 1.4e-54 184.2 1.6 1.4e-54 184.2 1.6 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein RVT_1 PF00078.27 GBG71715.1 - 2.3e-28 99.3 0.1 3.4e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71715.1 - 2.4e-27 94.9 0.0 5.5e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71715.1 - 1.2e-25 89.8 0.0 2.3e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71715.1 - 2.3e-19 69.3 0.4 6.5e-19 67.8 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG71715.1 - 0.13 12.5 0.0 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 H2C2 zinc finger Coilin_N PF15862.5 GBG71716.1 - 0.15 11.9 2.8 0.26 11.1 2.8 1.4 1 0 0 1 1 1 0 Coilin N-terminus VWA_2 PF13519.6 GBG71717.1 - 9.9e-10 39.0 0.0 2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GBG71717.1 - 0.017 15.4 0.1 0.05 13.8 0.1 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain INT_SG_DDX_CT_C PF15300.6 GBG71717.1 - 0.034 13.9 0.0 0.083 12.7 0.0 1.7 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus DDE_Tnp_4 PF13359.6 GBG71718.1 - 5e-25 88.0 0.0 9.8e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71718.1 - 5.4e-10 39.2 0.0 8.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71718.1 - 0.004 16.8 0.3 0.038 13.6 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG71718.1 - 0.068 13.5 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 Transposase DDE domain Cyclin_N PF00134.23 GBG71719.1 - 6e-23 81.0 0.9 1.2e-22 80.0 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GBG71719.1 - 1.2e-12 48.0 0.1 2.1e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain CDC45 PF02724.14 GBG71719.1 - 0.16 10.2 13.1 0.27 9.5 13.1 1.3 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 GBG71719.1 - 6.3 6.3 19.5 0.19 11.3 12.2 2.1 2 0 0 2 2 2 0 PPP4R2 DUF374 PF04028.13 GBG71720.1 - 0.026 14.1 10.6 4.3 7.0 0.1 5.2 4 2 2 6 6 6 0 Domain of unknown function (DUF374) EPSP_synthase PF00275.20 GBG71721.1 - 4.2 5.9 9.6 5.7 5.5 1.2 2.1 1 1 1 2 2 2 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Chloroa_b-bind PF00504.21 GBG71722.1 - 2.7e-48 164.6 0.0 3.4e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein GCK PF07802.11 GBG71723.1 - 0.082 13.3 0.3 0.25 11.8 0.3 1.9 1 0 0 1 1 1 0 GCK domain Myb_DNA-binding PF00249.31 GBG71724.1 - 6e-08 32.8 0.5 1.1e-07 32.0 0.5 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG71724.1 - 4e-06 27.0 0.2 7.4e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 GBG71724.1 - 0.0081 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 SLIDE Retrotrans_gag PF03732.17 GBG71725.1 - 0.002 18.4 2.5 0.009 16.3 0.1 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG71725.1 - 0.0096 15.7 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease CENP-K PF11802.8 GBG71725.1 - 0.035 13.7 2.5 0.058 13.0 2.5 1.3 1 0 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 GBG71725.1 - 0.1 12.5 16.3 0.17 11.8 16.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PTS_EIIA_2 PF00359.22 GBG71725.1 - 0.2 11.6 1.0 9.4 6.1 0.1 2.5 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF3801 PF12687.7 GBG71725.1 - 0.53 10.3 4.4 1.1 9.4 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DUF3499 PF12005.8 GBG71725.1 - 2.3 8.8 9.0 2.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Dimer_Tnp_hAT PF05699.14 GBG71726.1 - 8.3e-10 38.3 0.2 1.9e-09 37.2 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region tRNA_U5-meth_tr PF05958.11 GBG71727.1 - 6.1e-20 71.5 0.0 5e-19 68.5 0.0 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GBG71727.1 - 3.2e-13 49.7 0.0 7.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG71727.1 - 3.6e-10 40.4 0.2 1.6e-09 38.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GBG71727.1 - 1.7e-06 27.7 0.0 3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 GBG71727.1 - 4.2e-05 23.2 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 GBG71727.1 - 6.5e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 GBG71727.1 - 0.00011 22.8 0.1 0.00084 19.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 GBG71727.1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 GBG71727.1 - 0.00035 20.3 0.7 0.011 15.4 0.7 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 GBG71727.1 - 0.00037 20.0 0.0 0.0014 18.1 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 GBG71727.1 - 0.0056 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GBG71727.1 - 0.014 16.2 0.0 0.033 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GBG71727.1 - 0.038 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 GBG71727.1 - 0.048 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 GBG71727.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase N6_N4_Mtase PF01555.18 GBG71727.1 - 0.21 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 DNA methylase tRNA_U5-meth_tr PF05958.11 GBG71728.1 - 6.9e-20 71.3 0.0 5.7e-19 68.3 0.0 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GBG71728.1 - 3.4e-13 49.6 0.0 7.8e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG71728.1 - 3.8e-10 40.3 0.1 1.7e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GBG71728.1 - 1.8e-06 27.6 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 GBG71728.1 - 4.5e-05 23.1 0.0 8.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 GBG71728.1 - 6.7e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 GBG71728.1 - 0.00012 22.6 0.1 0.00089 19.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 GBG71728.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 GBG71728.1 - 0.00039 20.2 0.7 0.011 15.4 0.7 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 GBG71728.1 - 0.0004 19.9 0.0 0.0015 18.0 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 GBG71728.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GBG71728.1 - 0.014 16.1 0.0 0.035 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GBG71728.1 - 0.039 13.7 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 GBG71728.1 - 0.051 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 GBG71728.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase N6_N4_Mtase PF01555.18 GBG71728.1 - 0.21 11.2 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Menin PF05053.13 GBG71730.1 - 0.019 13.4 0.2 0.025 12.9 0.2 1.2 1 0 0 1 1 1 0 Menin Methyltransf_12 PF08242.12 GBG71730.1 - 0.4 11.4 4.1 3.7 8.4 0.2 2.4 2 0 0 2 2 2 0 Methyltransferase domain DUF2076 PF09849.9 GBG71730.1 - 0.43 10.6 11.2 0.71 9.9 11.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Orf78 PF06024.12 GBG71730.1 - 2.2 8.6 5.1 3.4 8.0 0.4 2.2 2 0 0 2 2 2 0 Orf78 (ac78) CENP-B_dimeris PF09026.10 GBG71730.1 - 6 7.3 8.8 6.9 7.1 3.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PHO4 PF01384.20 GBG71731.1 - 9.9e-106 353.6 25.4 9.9e-106 353.6 25.4 1.8 2 0 0 2 2 2 1 Phosphate transporter family HTH_IclR PF09339.10 GBG71731.1 - 0.0015 18.3 0.0 2.8 7.8 0.0 2.7 2 0 0 2 2 2 2 IclR helix-turn-helix domain Dehydrin PF00257.19 GBG71731.1 - 8.7 6.9 11.1 0.88 10.1 5.0 2.3 2 0 0 2 2 2 0 Dehydrin DUF3574 PF12098.8 GBG71732.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Sigma70_r4 PF04545.16 GBG71733.1 - 5.9e-11 41.7 0.1 1.2e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 GBG71733.1 - 0.0082 16.1 0.0 0.024 14.6 0.0 1.9 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 GerE PF00196.19 GBG71733.1 - 0.071 12.7 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 GBG71733.1 - 0.075 12.7 0.1 0.2 11.4 0.1 1.8 1 1 0 1 1 1 0 Sigma-70, region 4 VIR_N PF15912.5 GBG71733.1 - 0.25 10.9 6.5 0.62 9.6 6.5 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal Nop14 PF04147.12 GBG71735.1 - 0.37 8.9 46.0 0.49 8.5 46.0 1.0 1 0 0 1 1 1 0 Nop14-like family Smg8_Smg9 PF10220.9 GBG71735.1 - 4.1 5.6 8.3 5.8 5.1 8.3 1.2 1 0 0 1 1 1 0 Smg8_Smg9 MnmE_helical PF12631.7 GBG71736.1 - 1.1e-48 166.1 0.0 2.3e-48 165.1 0.0 1.5 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 GBG71736.1 - 9.7e-37 125.8 0.0 9.7e-37 125.8 0.0 2.2 2 0 0 2 2 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 GBG71736.1 - 1.1e-23 83.5 0.3 5.7e-23 81.2 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG71736.1 - 2.8e-08 33.4 0.2 9.7e-08 31.7 0.2 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 GBG71736.1 - 0.00018 20.9 0.1 0.00034 20.0 0.1 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 GBG71736.1 - 0.0038 17.3 0.5 0.25 11.4 0.1 2.7 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 GBG71736.1 - 0.022 15.1 0.0 0.082 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 GBG71736.1 - 0.07 12.7 3.4 0.92 9.0 0.0 3.3 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain Ras PF00071.22 GBG71736.1 - 0.081 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 GBG71736.1 - 0.086 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase PRIMA1 PF16101.5 GBG71736.1 - 4.6 7.3 11.9 12 6.0 11.9 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Med8 PF10232.9 GBG71736.1 - 10 5.7 8.8 0.74 9.4 0.3 2.6 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 SWIB PF02201.18 GBG71737.1 - 5.9e-25 87.0 0.0 2.3e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain Mo25 PF08569.11 GBG71738.1 - 6.9e-99 331.3 8.7 7.9e-99 331.1 8.7 1.0 1 0 0 1 1 1 1 Mo25-like DUF1759 PF03564.15 GBG71738.1 - 0.002 18.1 1.0 0.81 9.6 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1759) V-ATPase_H_C PF11698.8 GBG71738.1 - 0.018 15.1 0.3 4.4 7.4 0.0 2.9 3 0 0 3 3 3 0 V-ATPase subunit H SAS-6_N PF16531.5 GBG71743.1 - 4.5e-27 94.5 0.5 6.3e-27 94.0 0.5 1.2 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal ATP-synt_Eps PF04627.13 GBG71743.1 - 0.018 15.0 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain RVT_1 PF00078.27 GBG71746.1 - 8.4e-25 87.6 0.0 2.1e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71746.1 - 5.4e-13 48.8 0.1 2.3e-12 46.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG71746.1 - 3.1e-07 30.9 0.0 7.8e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71746.1 - 4e-07 30.6 0.0 1e-06 29.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71746.1 - 1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71746.1 - 0.00011 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG71746.1 - 0.0041 17.4 1.0 0.0091 16.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase LUC7 PF03194.15 GBG71746.1 - 0.015 14.9 1.1 0.027 14.1 1.1 1.3 1 0 0 1 1 1 0 LUC7 N_terminus UPF0184 PF03670.13 GBG71746.1 - 0.21 12.0 0.9 16 6.0 0.0 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) ABC_tran_CTD PF16326.5 GBG71746.1 - 0.26 11.5 4.5 0.62 10.4 1.9 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain TSC22 PF01166.18 GBG71746.1 - 0.52 10.7 2.0 3.3 8.1 1.4 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Retrotrans_gag PF03732.17 GBG71746.1 - 0.61 10.4 11.7 0.036 14.3 2.8 3.3 2 1 1 3 3 3 0 Retrotransposon gag protein NPV_P10 PF05531.12 GBG71746.1 - 1.1 9.8 5.4 21 5.7 3.1 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 GBG71746.1 - 1.3 9.4 3.3 68 3.9 2.2 3.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 GBG71746.1 - 1.9 9.0 10.6 1.4 9.5 6.9 2.6 2 1 0 2 2 2 0 Cell division protein ZapB TANGO2 PF05742.12 GBG71747.1 - 1.2e-46 159.8 0.0 7.9e-43 147.3 0.0 2.3 2 1 0 2 2 2 2 Transport and Golgi organisation 2 Nop14 PF04147.12 GBG71747.1 - 0.49 8.5 12.2 0.58 8.3 12.2 1.0 1 0 0 1 1 1 0 Nop14-like family DARPP-32 PF05395.12 GBG71747.1 - 0.6 10.3 9.8 0.96 9.6 9.8 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 NOA36 PF06524.12 GBG71747.1 - 1.3 8.3 7.9 1.8 7.8 7.9 1.1 1 0 0 1 1 1 0 NOA36 protein P34-Arc PF04045.14 GBG71749.1 - 4.6e-54 183.7 0.0 7e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc P34-Arc PF04045.14 GBG71750.1 - 4.8e-54 183.6 0.0 6.5e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PPR_2 PF13041.6 GBG71751.1 - 1.1e-120 393.7 4.2 9.1e-18 64.2 0.0 13.1 5 2 8 13 13 13 12 PPR repeat family PPR_1 PF12854.7 GBG71751.1 - 7.6e-112 364.7 8.3 9.5e-10 38.0 0.0 14.4 14 0 0 14 14 14 13 PPR repeat PPR PF01535.20 GBG71751.1 - 4.2e-105 336.9 13.2 4.3e-10 39.1 0.0 15.5 15 1 0 15 15 15 12 PPR repeat PPR_3 PF13812.6 GBG71751.1 - 5.3e-84 276.3 0.0 2.6e-14 53.0 0.0 8.8 7 1 1 9 9 9 8 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG71751.1 - 1.2e-36 126.1 0.0 5.4e-11 42.3 0.0 5.2 1 1 4 6 6 6 5 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 GBG71751.1 - 9.2e-11 41.2 9.4 0.00021 20.3 0.0 4.7 2 1 3 5 5 4 3 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.6 GBG71751.1 - 1.4e-09 38.3 0.1 2 9.0 0.0 8.0 7 1 2 9 9 9 1 Tetratricopeptide repeat BTAD PF03704.17 GBG71751.1 - 2.8e-05 24.6 1.3 7 7.1 0.0 4.9 4 1 0 4 4 4 2 Bacterial transcriptional activator domain TPR_14 PF13428.6 GBG71751.1 - 4.2e-05 24.0 9.1 1.4e+02 3.7 0.0 9.4 7 2 4 11 11 8 0 Tetratricopeptide repeat ECSIT PF06239.11 GBG71751.1 - 4.4e-05 22.7 8.8 0.058 12.5 0.0 7.0 3 1 3 6 6 6 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.6 GBG71751.1 - 4.4e-05 23.2 2.8 18 5.6 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat Clathrin PF00637.20 GBG71751.1 - 0.00022 21.1 0.0 3.1 7.6 0.0 5.1 5 1 1 6 6 6 1 Region in Clathrin and VPS Smr PF01713.21 GBG71751.1 - 0.00068 20.0 0.0 0.0022 18.3 0.0 2.0 1 0 0 1 1 1 1 Smr domain TPR_12 PF13424.6 GBG71751.1 - 0.0026 18.0 11.3 1.3 9.4 0.0 7.1 8 1 0 8 8 7 1 Tetratricopeptide repeat PYRIN PF02758.16 GBG71751.1 - 0.0034 17.5 0.1 1 9.5 0.0 4.8 7 0 0 7 7 5 1 PAAD/DAPIN/Pyrin domain TPR_8 PF13181.6 GBG71751.1 - 0.0058 16.8 1.7 13 6.3 0.0 5.1 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF5490 PF17593.2 GBG71751.1 - 0.012 15.6 2.1 7.7 6.6 0.1 5.9 10 0 0 10 10 8 0 Family of unknown function (DUF5490) Coatomer_E PF04733.14 GBG71751.1 - 0.013 14.9 0.0 8.8 5.6 0.0 3.2 3 0 0 3 3 3 0 Coatomer epsilon subunit TPR_4 PF07721.14 GBG71751.1 - 0.046 14.4 7.4 3 8.7 0.1 6.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TFIIA PF03153.13 GBG71751.1 - 0.054 13.5 32.9 0.053 13.5 11.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH_2 PF17919.1 GBG71752.1 - 6.7e-30 103.1 0.0 3.9e-29 100.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71752.1 - 5.2e-27 94.2 0.0 2.2e-26 92.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71752.1 - 2.5e-24 86.1 0.1 3.7e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4746 PF15928.5 GBG71752.1 - 3.3 7.1 10.4 5.2 6.4 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDE_Tnp_4 PF13359.6 GBG71756.1 - 3.2e-28 98.4 0.0 1.1e-26 93.4 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71756.1 - 5.7e-12 45.7 0.0 9.9e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71756.1 - 0.00068 19.3 0.1 0.66 9.6 0.0 3.0 3 0 0 3 3 3 2 Transposase DDE domain DUF4360 PF14273.6 GBG71757.1 - 1.1e-46 159.0 0.1 1.2e-46 158.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DDE_Tnp_4 PF13359.6 GBG71758.1 - 1.4e-14 54.1 0.0 2.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71758.1 - 2.9e-05 23.8 0.0 5.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein RVT_1 PF00078.27 GBG71760.1 - 5.9e-09 35.8 0.0 2.2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG71760.1 - 7.8e-08 32.9 0.9 0.022 15.4 0.1 2.8 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG71760.1 - 2e-06 27.6 0.1 0.089 12.6 0.0 2.3 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 GBG71760.1 - 1.4e-05 24.9 0.7 0.19 11.5 0.1 2.5 2 0 0 2 2 2 2 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG71760.1 - 0.00037 20.1 2.3 0.74 9.5 0.1 2.8 2 0 0 2 2 2 2 Topoisomerase I zinc-ribbon-like cNMP_binding PF00027.29 GBG71760.1 - 0.0019 18.3 0.0 4.3 7.5 0.0 2.9 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF4992 PF16383.5 GBG71760.1 - 0.012 15.1 0.0 7.3 6.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function TetR_C_9 PF14514.6 GBG71760.1 - 0.084 13.0 0.0 26 5.0 0.0 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Gryzun PF07919.12 GBG71760.1 - 0.14 10.9 0.2 11 4.7 0.0 2.1 2 0 0 2 2 2 0 Gryzun, putative trafficking through Golgi DUF3869 PF12985.7 GBG71760.1 - 0.24 11.8 0.9 7.6 7.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3869) AfaD PF05775.12 GBG71760.1 - 0.39 11.2 1.7 52 4.4 0.1 3.2 2 2 0 2 2 2 0 Enterobacteria AfaD invasin protein TadF PF16964.5 GBG71763.1 - 0.1 12.4 1.9 0.23 11.2 1.9 1.6 1 0 0 1 1 1 0 Putative tight adherence pilin protein F DUF4360 PF14273.6 GBG71764.1 - 1.5e-45 155.2 0.1 1.8e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG71765.1 - 1.9e-39 135.4 0.0 2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DDE_Tnp_4 PF13359.6 GBG71766.1 - 5.4e-29 100.9 0.0 9.6e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71766.1 - 1.1e-09 38.1 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DUF4360 PF14273.6 GBG71767.1 - 1.5e-44 152.0 0.1 1.9e-44 151.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Podoplanin PF05808.11 GBG71769.1 - 3.9 7.6 18.1 0.82 9.8 2.2 3.4 2 1 2 4 4 4 0 Podoplanin DUF4360 PF14273.6 GBG71770.1 - 2e-40 138.6 0.5 2.2e-40 138.4 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NOA36 PF06524.12 GBG71773.1 - 0.11 11.8 26.2 0.19 11.1 26.2 1.4 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 GBG71773.1 - 0.12 12.2 12.4 0.2 11.5 12.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.11 GBG71773.1 - 1.6 8.3 20.4 2.3 7.7 20.4 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GBG71773.1 - 8.6 4.4 26.9 11 4.1 26.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4360 PF14273.6 GBG71774.1 - 3.6e-40 137.7 0.4 4.1e-40 137.5 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG71776.1 - 2e-35 122.3 0.1 2.3e-35 122.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Big_7 PF17957.1 GBG71776.1 - 0.062 14.1 0.5 1.5 9.7 0.0 2.6 1 1 0 2 2 2 0 Bacterial Ig domain DUF4360 PF14273.6 GBG71786.1 - 5.3e-39 133.9 0.0 6.1e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF659 PF04937.15 GBG71788.1 - 4.6e-25 88.3 0.0 7.5e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) USP8_interact PF08941.10 GBG71789.1 - 0.015 15.2 0.7 0.49 10.2 0.0 2.3 2 0 0 2 2 2 0 USP8 interacting MPLKIP PF15502.6 GBG71789.1 - 6.2 7.1 6.0 6.8 7.0 0.9 2.5 2 0 0 2 2 2 0 M-phase-specific PLK1-interacting protein DUF4360 PF14273.6 GBG71791.1 - 3.6e-38 131.2 0.0 3.9e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG71792.1 - 3.2e-31 107.3 0.0 8.1e-31 106.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71792.1 - 2.4e-30 104.9 0.1 7e-30 103.4 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG71792.1 - 0.021 14.7 0.4 0.076 12.9 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain SRR1 PF07985.12 GBG71792.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 SRR1 gpUL132 PF11359.8 GBG71792.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 DUF4360 PF14273.6 GBG71793.1 - 5.4e-36 124.1 1.9 6.5e-36 123.9 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) UPF0560 PF10577.9 GBG71794.1 - 1.3 7.4 7.5 2.6 6.4 7.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4360 PF14273.6 GBG71796.1 - 1.4e-43 148.8 0.5 1.7e-43 148.6 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Histone PF00125.24 GBG71797.1 - 2.7e-22 79.5 0.0 7.9e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-CCHC PF00098.23 GBG71797.1 - 0.29 11.3 0.9 0.5 10.5 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG71797.1 - 0.34 10.6 1.6 0.59 9.8 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Myb_DNA-bind_4 PF13837.6 GBG71798.1 - 6.8e-06 26.4 1.8 1e-05 25.8 1.8 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TetR_C_24 PF17932.1 GBG71798.1 - 0.013 15.8 0.1 0.025 14.8 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Myb_DNA-bind_5 PF13873.6 GBG71798.1 - 0.051 13.7 0.4 0.085 12.9 0.4 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF4360 PF14273.6 GBG71799.1 - 4e-39 134.3 2.5 4.5e-39 134.1 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Defensin_propep PF00879.18 GBG71799.1 - 0.21 11.9 0.8 0.36 11.1 0.8 1.3 1 0 0 1 1 1 0 Defensin propeptide DUF4360 PF14273.6 GBG71800.1 - 2.4e-28 99.2 0.0 3.3e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CCSAP PF15748.5 GBG71801.1 - 6.5 6.9 20.2 8.6 6.5 20.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated YL1 PF05764.13 GBG71802.1 - 0.017 15.2 16.1 0.021 14.9 16.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SMN PF06003.12 GBG71802.1 - 0.1 11.9 3.7 0.13 11.5 3.7 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Presenilin PF01080.17 GBG71802.1 - 1.5 7.5 4.3 1.7 7.3 4.3 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG71802.1 - 1.8 6.7 15.9 2.4 6.3 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG71802.1 - 2 7.7 15.1 2.4 7.5 15.1 1.1 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 GBG71802.1 - 3.3 7.5 9.5 4.8 6.9 9.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVT_1 PF00078.27 GBG71803.1 - 3.3e-29 102.0 0.1 5.1e-29 101.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71803.1 - 7.3e-23 80.5 0.0 1.9e-22 79.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71803.1 - 9.3e-20 70.9 0.0 1.7e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG71803.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 ST7 PF04184.12 GBG71803.1 - 0.11 11.0 0.1 0.18 10.3 0.1 1.2 1 0 0 1 1 1 0 ST7 protein DUF4360 PF14273.6 GBG71804.1 - 2.4e-46 157.8 0.0 2.7e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG71805.1 - 3.7e-34 118.2 0.4 4.2e-34 118.0 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) BUD22 PF09073.10 GBG71807.1 - 0.2 11.0 22.1 0.24 10.7 22.1 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG71807.1 - 2.2 6.4 23.9 2.6 6.1 23.9 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4360 PF14273.6 GBG71808.1 - 7.3e-37 127.0 1.7 1e-36 126.5 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG71809.1 - 4.1e-29 100.6 0.0 8.2e-29 99.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71809.1 - 1.3e-26 93.5 0.0 2.6e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71809.1 - 3.3e-25 88.4 0.1 9.1e-25 87.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71809.1 - 1.1e-14 54.3 0.0 4.3e-14 52.4 0.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71809.1 - 2.3e-13 50.4 0.0 4.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG71809.1 - 7.3e-05 23.3 0.0 0.00019 21.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG71809.1 - 0.00012 21.9 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71809.1 - 0.00036 21.1 0.0 0.00083 19.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG71809.1 - 0.025 14.8 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger GSHPx PF00255.19 GBG71809.1 - 0.074 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione peroxidase Rhamno_transf PF11316.8 GBG71809.1 - 0.13 11.6 0.1 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative rhamnosyl transferase STI1 PF17830.1 GBG71809.1 - 0.15 12.0 0.2 0.59 10.1 0.2 2.0 1 0 0 1 1 1 0 STI1 domain RVT_1 PF00078.27 GBG71810.1 - 9.3e-41 139.8 0.4 9.4e-31 107.0 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71810.1 - 9e-31 106.3 0.0 2.2e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71810.1 - 2.4e-30 104.5 0.0 6.2e-30 103.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_S8 PF00082.22 GBG71810.1 - 9.2e-27 94.1 2.6 2.3e-26 92.8 2.6 1.5 1 0 0 1 1 1 1 Subtilase family RVP_2 PF08284.11 GBG71810.1 - 2.3e-17 63.0 0.0 2.4e-07 30.6 0.0 3.4 3 0 0 3 3 3 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG71810.1 - 9.9e-16 58.2 0.0 5.2e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG71810.1 - 1.7e-12 47.7 0.0 5.8e-05 23.6 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG71810.1 - 1.2e-09 38.3 0.0 2.8e-08 34.0 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG71810.1 - 1.4e-09 38.0 0.1 6.9e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain DUF1758 PF05585.12 GBG71810.1 - 1.9e-06 27.8 0.0 0.00013 21.8 0.0 2.5 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG71810.1 - 0.004 16.9 0.0 0.093 12.5 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG71810.1 - 0.0053 17.0 0.0 0.61 10.4 0.0 2.8 2 1 0 2 2 2 1 Retroviral aspartyl protease Peptidase_A3 PF02160.15 GBG71810.1 - 0.05 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) RT_RNaseH_2 PF17919.1 GBG71811.1 - 7.1e-33 112.6 0.0 1.4e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71811.1 - 1.1e-28 99.5 0.0 2.2e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71811.1 - 1.6e-19 69.8 0.1 3.3e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG71811.1 - 3.3e-12 46.4 0.3 5.9e-12 45.6 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG71811.1 - 0.00015 21.9 0.0 0.00049 20.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG71811.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Crp PF00325.20 GBG71812.1 - 0.0013 18.3 1.4 16 5.3 0.0 4.6 4 1 1 5 5 5 3 Bacterial regulatory proteins, crp family EGF_2 PF07974.13 GBG71815.1 - 0.0019 18.5 6.9 0.0019 18.5 6.9 3.5 4 0 0 4 4 4 1 EGF-like domain RVT_1 PF00078.27 GBG71816.1 - 1.5e-31 109.6 0.1 2.5e-31 108.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71816.1 - 1.3e-29 102.2 0.0 3e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71816.1 - 5.7e-29 100.5 0.0 1.4e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG71816.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG71816.1 - 0.018 15.2 0.1 0.018 15.2 0.1 2.2 2 0 0 2 2 2 0 Integrase zinc binding domain zf-C2H2 PF00096.26 GBG71816.1 - 0.21 12.1 0.9 0.72 10.4 0.9 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Arc_PepC_II PF06847.11 GBG71816.1 - 9.4 6.8 6.5 13 6.4 0.0 3.8 3 1 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II RT_RNaseH_2 PF17919.1 GBG71817.1 - 1.9e-33 114.4 0.7 3.4e-33 113.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71817.1 - 2e-27 95.5 0.3 5.2e-27 94.2 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71817.1 - 6.5e-23 81.4 0.0 1.5e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG71817.1 - 3.2e-18 65.6 0.5 8e-18 64.3 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG71817.1 - 0.027 14.1 4.7 4.3 6.9 0.0 2.5 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Tho1_MOS11_C PF18592.1 GBG71817.1 - 0.047 13.5 0.8 0.15 11.9 0.8 1.8 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain CENP-Q PF13094.6 GBG71817.1 - 0.058 13.6 6.3 0.13 12.4 6.3 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NPV_P10 PF05531.12 GBG71817.1 - 0.17 12.4 0.1 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG71818.1 - 3.5e-21 75.7 0.1 5.9e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG71818.1 - 0.0012 19.1 0.0 0.0043 17.3 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG71820.1 - 6e-28 97.9 0.0 8.8e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LMBR1 PF04791.16 GBG71820.1 - 0.29 10.0 2.2 0.42 9.4 2.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RT_RNaseH_2 PF17919.1 GBG71821.1 - 2.6e-28 98.0 0.0 9.8e-28 96.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71821.1 - 2.5e-27 95.9 0.0 2.2e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71821.1 - 4.1e-26 91.3 0.0 1.6e-25 89.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71821.1 - 8e-16 57.9 0.1 3.1e-15 56.0 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG71821.1 - 4.5e-09 36.5 0.2 2.5e-08 34.1 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain Retrotrans_gag PF03732.17 GBG71821.1 - 0.0064 16.8 1.1 0.089 13.1 0.1 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein AP1AR PF15745.5 GBG71821.1 - 0.75 9.4 7.0 1.3 8.6 7.0 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein HIP1_clath_bdg PF16515.5 GBG71821.1 - 1.4 9.6 16.9 0.16 12.6 10.1 2.8 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RNA_polI_A34 PF08208.11 GBG71822.1 - 6.6 6.8 7.4 10 6.2 7.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF659 PF04937.15 GBG71823.1 - 4.9e-38 130.4 0.0 9.3e-38 129.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG71823.1 - 0.032 14.0 0.2 0.066 13.0 0.2 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region NR_Repeat PF14046.6 GBG71823.1 - 0.036 14.2 0.5 0.097 12.8 0.5 1.7 1 0 0 1 1 1 0 Nuclear receptor repeat Myco_haema PF05692.12 GBG71824.1 - 0.33 9.9 6.4 0.062 12.3 2.6 1.6 2 0 0 2 2 2 0 Mycoplasma haemagglutinin LysM PF01476.20 GBG71825.1 - 5.9e-13 48.7 0.1 7e-10 38.8 0.1 2.3 2 0 0 2 2 2 2 LysM domain Flagellin_IN PF07196.13 GBG71825.1 - 0.011 15.9 0.7 6.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Flagellin hook IN motif DDE_Tnp_4 PF13359.6 GBG71826.1 - 2e-20 73.1 0.0 5.9e-20 71.5 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71826.1 - 3.9e-12 46.2 0.0 1.2e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Plant transposon protein ZapB PF06005.12 GBG71826.1 - 0.00018 21.8 0.9 0.033 14.6 0.4 2.4 2 0 0 2 2 2 1 Cell division protein ZapB Cep57_CLD PF14073.6 GBG71826.1 - 0.0028 17.7 2.9 0.0043 17.1 2.9 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 BicD PF09730.9 GBG71826.1 - 0.0058 15.1 0.9 0.0078 14.7 0.9 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D MAR_sialic_bdg PF10564.9 GBG71826.1 - 0.0076 16.3 2.1 0.02 14.9 2.1 1.8 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat APG6_N PF17675.1 GBG71826.1 - 0.013 16.1 4.5 0.039 14.5 0.3 2.5 3 0 0 3 3 2 0 Apg6 coiled-coil region ADIP PF11559.8 GBG71826.1 - 0.015 15.4 4.2 0.026 14.6 1.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 GBG71826.1 - 0.022 14.5 1.1 1.7 8.5 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.12 GBG71826.1 - 0.029 14.4 5.9 0.33 11.0 1.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF713 PF05218.14 GBG71826.1 - 0.032 14.0 2.0 0.058 13.1 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) CCDC106 PF15794.5 GBG71826.1 - 0.057 13.1 1.3 0.07 12.8 0.5 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Tropomyosin_1 PF12718.7 GBG71826.1 - 0.39 10.9 3.8 8.4 6.5 0.7 2.2 2 0 0 2 2 2 0 Tropomyosin like NEMO PF11577.8 GBG71826.1 - 0.49 10.5 5.3 0.083 12.9 1.4 1.8 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO UPF0242 PF06785.11 GBG71826.1 - 4 7.5 6.8 44 4.1 6.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus IL13 PF03487.13 GBG71827.1 - 0.35 10.7 3.5 0.14 11.9 0.4 1.9 2 0 0 2 2 2 0 Interleukin-13 DUF1403 PF07183.11 GBG71830.1 - 0.027 14.0 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) RVT_1 PF00078.27 GBG71831.1 - 2.7e-22 79.4 0.0 6.6e-22 78.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG71831.1 - 0.00023 21.4 8.7 0.0041 17.4 0.0 4.1 3 0 0 3 3 3 1 Retrotransposon gag protein ERM PF00769.19 GBG71831.1 - 0.092 12.5 23.2 0.21 11.4 23.2 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.19 GBG71831.1 - 1.7 6.5 7.4 2.6 5.8 7.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.11 GBG71831.1 - 1.9 9.1 9.0 1.1 9.8 3.8 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.9 GBG71831.1 - 2.8 8.3 8.9 1.4 9.3 4.0 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0449 PF15136.6 GBG71831.1 - 3.9 8.0 12.8 13 6.3 8.2 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 NPV_P10 PF05531.12 GBG71831.1 - 4.4 7.8 7.2 16 6.1 0.8 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein WDCP PF15390.6 GBG71831.1 - 4.4 5.6 8.2 7.5 4.8 8.2 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family HIP1_clath_bdg PF16515.5 GBG71831.1 - 4.7 7.9 26.0 1.2 9.8 15.0 3.1 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RT_RNaseH_2 PF17919.1 GBG71833.1 - 4.2e-25 87.7 0.0 1e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71833.1 - 8.8e-23 80.6 0.0 1.8e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CRS1_YhbY PF01985.21 GBG71833.1 - 9.8e-17 60.9 0.2 2.6e-16 59.6 0.2 1.8 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain Retrotrans_gag PF03732.17 GBG71833.1 - 1.8e-05 24.9 1.6 0.026 14.8 0.0 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein RVT_1 PF00078.27 GBG71833.1 - 0.033 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71834.1 - 4.2e-25 87.7 0.0 1e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71834.1 - 8.8e-23 80.6 0.0 1.8e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CRS1_YhbY PF01985.21 GBG71834.1 - 9.8e-17 60.9 0.2 2.6e-16 59.6 0.2 1.8 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain Retrotrans_gag PF03732.17 GBG71834.1 - 1.8e-05 24.9 1.6 0.026 14.8 0.0 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein RVT_1 PF00078.27 GBG71834.1 - 0.033 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 GBG71839.1 - 2.1e-08 33.8 0.3 4.4e-08 32.8 0.3 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region G8 PF10162.9 GBG71841.1 - 5.7e-25 87.8 0.1 1.5e-18 67.0 0.0 2.4 2 0 0 2 2 2 2 G8 domain BSP_II PF05432.11 GBG71841.1 - 0.0011 18.7 22.5 0.0018 18.1 22.5 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF3381 PF11861.8 GBG71841.1 - 0.039 13.8 3.0 0.077 12.8 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DNA_pol_phi PF04931.13 GBG71841.1 - 1.1 7.2 14.6 1.6 6.7 14.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG71841.1 - 1.5 8.2 9.9 2.5 7.4 9.9 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG71841.1 - 3.5 6.9 11.5 5.4 6.2 11.5 1.2 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 GBG71841.1 - 3.5 5.9 10.7 5.6 5.3 10.7 1.2 1 0 0 1 1 1 0 Mpp10 protein Beta_helix PF13229.6 GBG71842.1 - 0.00016 21.5 9.8 0.0021 17.9 9.7 2.2 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 GBG71842.1 - 0.00097 18.5 4.3 0.0033 16.7 1.0 2.1 1 1 0 2 2 2 1 Periplasmic copper-binding protein (NosD) RT_RNaseH PF17917.1 GBG71845.1 - 4.2e-27 94.5 0.3 8.2e-27 93.6 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71845.1 - 3e-20 72.1 0.1 6.6e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Y_Y_Y PF07495.13 GBG71845.1 - 9.4e-05 22.3 0.0 1.1 9.3 0.0 4.4 4 0 0 4 4 4 1 Y_Y_Y domain Big_3_3 PF13750.6 GBG71845.1 - 0.00014 21.6 0.1 8.6 6.0 0.0 5.2 6 0 0 6 6 6 2 Bacterial Ig-like domain (group 3) Retrotrans_gag PF03732.17 GBG71845.1 - 0.0028 17.9 8.3 0.024 14.9 0.2 3.6 4 0 0 4 4 4 2 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG71845.1 - 0.036 14.0 0.6 0.084 12.9 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4187 PF13821.6 GBG71845.1 - 0.049 13.4 0.9 0.19 11.5 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) AAA_23 PF13476.6 GBG71845.1 - 2.9 8.3 6.1 15 6.0 1.0 2.7 2 0 0 2 2 2 0 AAA domain APG6_N PF17675.1 GBG71845.1 - 9.8 6.7 32.5 4.5 7.8 2.1 3.9 3 0 0 3 3 3 0 Apg6 coiled-coil region Cwf_Cwc_15 PF04889.12 GBG71847.1 - 0.093 12.5 19.8 0.15 11.8 19.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG71847.1 - 0.1 12.0 22.6 0.12 11.7 22.6 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG71847.1 - 0.62 9.3 21.6 0.79 9.0 21.6 1.1 1 0 0 1 1 1 0 BUD22 Zip PF02535.22 GBG71847.1 - 0.68 9.1 2.0 0.81 8.8 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 GBG71847.1 - 0.75 7.9 22.6 0.92 7.6 22.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG71847.1 - 1 7.5 18.1 1.3 7.2 18.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 GBG71847.1 - 1.8 6.6 7.0 2.3 6.2 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase_Tyr PF07714.17 GBG71848.1 - 1e-23 84.0 0.0 6.5e-23 81.3 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG71848.1 - 7.6e-18 64.8 0.0 2.6e-17 63.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GBG71848.1 - 0.0029 17.0 0.1 0.0061 15.9 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 GBG71849.1 - 8.6e-24 84.2 0.0 5.8e-23 81.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG71849.1 - 6.6e-18 65.0 0.0 2.3e-17 63.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GBG71849.1 - 0.0027 17.1 0.1 0.0057 16.0 0.1 1.6 1 1 0 1 1 1 1 Kinase-like IGPS PF00218.21 GBG71851.1 - 6.7e-78 261.4 0.0 7.4e-78 261.2 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase Melittin PF01372.17 GBG71851.1 - 4.7 7.4 5.0 2.2 8.4 0.1 2.9 3 1 0 3 3 3 0 Melittin RVT_1 PF00078.27 GBG71852.1 - 2.2e-27 96.0 0.1 3.3e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box-like PF12937.7 GBG71853.1 - 8.1e-08 32.1 0.9 8.1e-08 32.1 0.9 3.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GBG71853.1 - 1.6e-07 31.5 2.8 0.061 13.8 0.1 5.7 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG71853.1 - 7.4e-05 22.5 1.8 7.4e-05 22.5 1.8 3.0 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 GBG71853.1 - 0.00035 20.4 13.6 2 8.6 0.0 8.1 10 0 0 10 10 10 2 Leucine Rich repeat LRR_8 PF13855.6 GBG71853.1 - 0.01 15.6 2.8 1.6 8.5 0.1 4.4 6 1 0 6 6 6 0 Leucine rich repeat DUF3446 PF11928.8 GBG71853.1 - 5.5 7.4 9.3 26 5.2 7.7 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Pex14_N PF04695.13 GBG71855.1 - 6.5e-16 59.4 0.1 6.5e-16 59.4 0.1 1.6 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Retrotrans_gag PF03732.17 GBG71856.1 - 0.0067 16.7 1.9 0.065 13.5 0.0 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG71856.1 - 0.049 14.1 1.4 16 6.1 0.2 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 GBG71856.1 - 0.055 11.6 5.9 0.1 10.8 5.9 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CAP_N PF01213.19 GBG71856.1 - 0.11 11.9 0.8 0.21 11.0 0.8 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF489 PF04356.12 GBG71856.1 - 0.11 12.4 1.6 0.22 11.5 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) HrpB7 PF09486.10 GBG71856.1 - 0.81 10.1 13.9 0.3 11.5 10.0 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FlxA PF14282.6 GBG71856.1 - 1.5 8.9 11.3 6.6 6.8 0.1 2.7 2 0 0 2 2 2 0 FlxA-like protein DUF2802 PF10975.8 GBG71856.1 - 1.7 8.8 9.2 13 6.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Snapin_Pallidin PF14712.6 GBG71856.1 - 4.7 7.7 12.7 0.31 11.5 0.8 3.0 1 1 0 2 2 2 0 Snapin/Pallidin USP8_interact PF08941.10 GBG71856.1 - 9.1 6.1 7.5 2.1 8.1 2.3 2.5 2 2 0 2 2 2 0 USP8 interacting MIF4G_like_2 PF09090.11 GBG71857.1 - 0.11 12.0 4.7 0.18 11.3 4.7 1.2 1 0 0 1 1 1 0 MIF4G like PI3K_1B_p101 PF10486.9 GBG71857.1 - 0.2 9.4 1.2 0.27 8.9 1.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1980 PF09323.10 GBG71857.1 - 0.23 11.3 1.8 0.43 10.5 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RRN3 PF05327.11 GBG71857.1 - 1.6 7.2 7.7 2.3 6.6 7.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pex14_N PF04695.13 GBG71857.1 - 2 9.0 7.1 0.15 12.7 0.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nop14 PF04147.12 GBG71857.1 - 4.7 5.3 21.2 6.4 4.8 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG71857.1 - 5 6.4 21.5 7.3 5.9 21.5 1.2 1 0 0 1 1 1 0 SDA1 RT_RNaseH_2 PF17919.1 GBG71858.1 - 1.7e-18 66.5 0.0 4.6e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71858.1 - 3.2e-13 49.7 0.4 6.5e-13 48.7 0.4 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71858.1 - 2.3e-07 31.0 0.0 6.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5572 PF17733.1 GBG71859.1 - 6e-05 22.8 0.6 0.00023 20.9 0.6 2.1 1 0 0 1 1 1 1 Family of unknown function (DUF5572) PEGSRP PF07623.11 GBG71859.1 - 0.024 14.4 3.1 0.16 11.8 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) Trigger_C PF05698.14 GBG71860.1 - 2.6 8.0 10.6 6 6.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial trigger factor protein (TF) C-terminus DUF2076 PF09849.9 GBG71861.1 - 1.3 9.0 10.1 2 8.4 10.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Orf78 PF06024.12 GBG71861.1 - 2 8.8 6.4 3.2 8.1 6.4 1.3 1 0 0 1 1 1 0 Orf78 (ac78) FixS PF03597.15 GBG71862.1 - 0.29 10.9 9.2 3.5 7.4 1.3 3.1 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type Integrase_H2C2 PF17921.1 GBG71863.1 - 6.3e-13 48.6 0.0 1.4e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG71863.1 - 6.8e-11 42.4 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-RING_2 PF13639.6 GBG71864.1 - 2e-10 40.8 6.2 4.2e-10 39.8 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GBG71864.1 - 3.5e-09 36.8 7.0 1e-08 35.3 7.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GBG71864.1 - 4.9e-09 35.9 5.1 9.6e-09 34.9 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG71864.1 - 4.9e-08 32.7 6.1 8.5e-08 31.9 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG71864.1 - 1.7e-07 30.9 2.4 1.7e-07 30.9 2.4 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 GBG71864.1 - 3.5e-06 26.9 4.0 6.9e-06 25.9 4.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG71864.1 - 9.2e-06 25.6 1.7 1.3e-05 25.1 0.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GBG71864.1 - 0.00012 22.0 2.2 0.0003 20.8 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GBG71864.1 - 0.0046 16.8 5.1 0.0078 16.1 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF5427 PF10310.9 GBG71864.1 - 0.0086 15.1 6.4 0.014 14.4 6.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5427) TFIIA PF03153.13 GBG71864.1 - 0.018 15.1 8.7 0.029 14.4 8.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-Nse PF11789.8 GBG71864.1 - 0.046 13.5 2.0 0.092 12.6 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 GBG71864.1 - 0.051 13.7 5.7 0.094 12.9 5.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 GBG71864.1 - 0.19 11.4 3.2 0.42 10.3 3.2 1.5 1 0 0 1 1 1 0 P-11 zinc finger FANCL_C PF11793.8 GBG71864.1 - 0.25 11.6 5.6 2.1 8.6 5.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 GBG71864.1 - 0.76 10.1 4.9 2.2 8.6 4.9 1.9 1 0 0 1 1 1 0 RING-like domain PAT1 PF09770.9 GBG71864.1 - 1.5 7.0 10.2 2.2 6.5 10.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YppG PF14179.6 GBG71864.1 - 1.8 9.3 11.9 3.9 8.2 11.9 1.5 1 0 0 1 1 1 0 YppG-like protein Pex14_N PF04695.13 GBG71864.1 - 4.7 7.9 15.0 29 5.3 13.8 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_2 PF13639.6 GBG71865.1 - 4.2e-10 39.8 6.2 4.2e-10 39.8 6.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 GBG71865.1 - 3.3e-09 36.9 7.0 1e-08 35.3 7.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GBG71865.1 - 4e-09 36.2 5.1 9.5e-09 35.0 5.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG71865.1 - 3.8e-08 33.1 6.1 8.4e-08 32.0 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG71865.1 - 1.7e-07 30.9 2.4 1.7e-07 30.9 2.4 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 GBG71865.1 - 2.8e-06 27.2 4.0 6.8e-06 25.9 4.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG71865.1 - 7e-06 26.0 1.6 1.3e-05 25.1 0.6 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GBG71865.1 - 0.00012 22.1 2.2 0.0003 20.8 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GBG71865.1 - 0.0077 16.1 5.1 0.0077 16.1 5.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DUF5427 PF10310.9 GBG71865.1 - 0.0083 15.1 6.4 0.014 14.4 6.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5427) TFIIA PF03153.13 GBG71865.1 - 0.017 15.2 8.7 0.029 14.4 8.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-Nse PF11789.8 GBG71865.1 - 0.046 13.6 2.0 0.091 12.6 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 GBG71865.1 - 0.24 11.6 5.7 2.1 8.6 5.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PAT1 PF09770.9 GBG71865.1 - 1.5 7.0 10.3 2.1 6.5 10.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YppG PF14179.6 GBG71865.1 - 1.6 9.5 11.9 3.8 8.3 11.9 1.6 1 0 0 1 1 1 0 YppG-like protein Pex14_N PF04695.13 GBG71865.1 - 4.3 8.0 14.9 27 5.4 13.8 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_2 PF13639.6 GBG71866.1 - 2e-10 40.9 6.2 4.1e-10 39.8 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GBG71866.1 - 3.3e-09 36.9 7.0 1e-08 35.3 7.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GBG71866.1 - 4.9e-09 35.9 5.1 9.3e-09 35.0 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG71866.1 - 4.8e-08 32.7 6.1 8.2e-08 32.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG71866.1 - 1.6e-07 30.9 2.4 1.6e-07 30.9 2.4 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 GBG71866.1 - 3.4e-06 26.9 4.0 6.6e-06 26.0 4.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG71866.1 - 8.2e-06 25.7 1.6 1.2e-05 25.2 0.6 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GBG71866.1 - 0.00012 22.1 2.2 0.00029 20.8 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GBG71866.1 - 0.0046 16.8 5.1 0.0075 16.1 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF5427 PF10310.9 GBG71866.1 - 0.0082 15.2 6.4 0.013 14.5 6.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5427) TFIIA PF03153.13 GBG71866.1 - 0.015 15.3 8.6 0.025 14.6 8.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-Nse PF11789.8 GBG71866.1 - 0.045 13.6 2.0 0.089 12.6 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 GBG71866.1 - 0.05 13.8 5.7 0.091 12.9 5.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 GBG71866.1 - 0.19 11.4 3.2 0.41 10.4 3.2 1.5 1 0 0 1 1 1 0 P-11 zinc finger FANCL_C PF11793.8 GBG71866.1 - 0.24 11.6 5.7 2.1 8.6 5.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PAT1 PF09770.9 GBG71866.1 - 1.5 7.0 10.3 2.1 6.5 10.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YppG PF14179.6 GBG71866.1 - 1.7 9.4 11.9 3.7 8.3 11.9 1.6 1 0 0 1 1 1 0 YppG-like protein Pex14_N PF04695.13 GBG71866.1 - 3.3 8.3 14.6 27 5.4 13.8 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPT PF03151.16 GBG71867.1 - 3.2e-25 89.0 10.8 3.6e-25 88.9 10.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GBG71867.1 - 2e-08 33.8 10.6 2.5e-08 33.5 10.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GBG71867.1 - 1e-06 29.0 14.0 1e-06 29.0 14.0 1.5 2 0 0 2 2 2 1 EamA-like transporter family YwiC PF14256.6 GBG71867.1 - 0.067 13.5 6.8 0.49 10.7 1.5 2.2 1 1 1 2 2 2 0 YwiC-like protein MerC PF03203.14 GBG71867.1 - 5.3 7.5 12.0 1.4 9.3 8.6 1.8 2 1 0 2 2 2 0 MerC mercury resistance protein BAF250_C PF12031.8 GBG71870.1 - 0.0011 18.3 0.0 0.0034 16.7 0.0 1.8 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa RskA PF10099.9 GBG71870.1 - 0.02 15.2 11.3 0.48 10.7 0.7 3.0 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Arm PF00514.23 GBG71870.1 - 0.21 11.7 1.1 77 3.5 0.1 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4179 PF13786.6 GBG71870.1 - 2.4 8.7 5.6 40 4.8 1.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DUF4148 PF13663.6 GBG71870.1 - 5.4 7.3 11.3 3.5 7.9 2.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Beta_helix PF13229.6 GBG71871.1 - 4.4e-05 23.4 8.5 8.9e-05 22.4 7.8 1.9 1 1 0 1 1 1 1 Right handed beta helix region Chlorovi_GP_rpt PF06598.11 GBG71871.1 - 0.022 14.8 0.6 8.8 6.5 0.2 3.2 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat DUF4156 PF13698.6 GBG71871.1 - 0.038 14.3 0.2 15 6.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4156) Chlam_PMP PF02415.17 GBG71871.1 - 8.1 7.2 34.5 0.14 12.7 0.7 6.5 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Suf PF05843.14 GBG71872.1 - 0.012 15.6 3.0 0.025 14.6 3.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3603 PF12227.8 GBG71872.1 - 0.043 13.1 5.2 0.025 13.9 2.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3603) Retrotrans_gag PF03732.17 GBG71872.1 - 0.05 13.9 0.3 0.25 11.6 0.2 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein Presenilin PF01080.17 GBG71872.1 - 0.28 9.9 5.3 0.4 9.4 5.3 1.2 1 0 0 1 1 1 0 Presenilin Ta0938 PF11494.8 GBG71872.1 - 1.1 9.6 5.3 6.4 7.1 0.1 3.1 3 0 0 3 3 3 0 Ta0938 GUN4 PF05419.12 GBG71873.1 - 7.9e-52 175.1 0.1 1.1e-51 174.6 0.1 1.2 1 0 0 1 1 1 1 GUN4-like zf-CCHC PF00098.23 GBG71874.1 - 2.8e-06 27.2 4.5 2.8e-06 27.2 4.5 1.6 2 0 0 2 2 2 1 Zinc knuckle Rap1_C PF11626.8 GBG71874.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-CCHC_4 PF14392.6 GBG71874.1 - 0.15 11.8 1.8 0.34 10.7 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG71874.1 - 0.2 11.5 5.0 0.31 10.9 5.0 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG71876.1 - 1.2e-34 119.8 0.1 1.9e-34 119.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71876.1 - 1.5e-23 82.7 0.0 4.7e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71876.1 - 4.1e-12 46.3 0.0 9.4e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Senescence PF06911.12 GBG71878.1 - 1.1e-30 107.3 3.3 2e-30 106.5 3.3 1.4 1 0 0 1 1 1 1 Senescence-associated protein Phenol_Hydrox PF02332.18 GBG71878.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase SAPS PF04499.15 GBG71879.1 - 0.054 12.3 2.4 0.053 12.3 2.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Serinc PF03348.15 GBG71879.1 - 0.54 9.1 0.7 0.83 8.5 0.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nop53 PF07767.11 GBG71879.1 - 0.83 9.0 26.9 1.3 8.3 26.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BUD22 PF09073.10 GBG71879.1 - 1 8.6 26.1 1.7 7.9 26.1 1.3 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GBG71879.1 - 1.3 8.6 22.6 2.2 7.9 22.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG71879.1 - 1.7 6.9 18.3 2.1 6.5 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG71879.1 - 3.2 5.9 28.2 4.5 5.3 28.2 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG71879.1 - 5.6 6.3 29.1 7.6 5.9 29.1 1.1 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.10 GBG71879.1 - 7.1 6.9 15.3 15 5.9 15.3 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RT_RNaseH PF17917.1 GBG71880.1 - 4.5e-22 78.3 0.0 1.2e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71880.1 - 2.2e-20 72.6 0.0 4.4e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71880.1 - 4.6e-07 29.6 0.0 8.1e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG71880.1 - 1.4e-06 28.7 0.0 3.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG71880.1 - 1.6e-05 24.7 0.1 2.9e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG71880.1 - 3.3e-05 24.5 0.1 7.2e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71880.1 - 0.0024 17.6 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG71880.1 - 0.14 12.3 1.7 0.24 11.5 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHH PF10283.9 GBG71881.1 - 6.2 6.9 11.0 13 5.9 1.8 2.5 2 0 0 2 2 2 0 PBZ domain MCM PF00493.23 GBG71882.1 - 9e-101 335.6 0.0 1.2e-100 335.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 GBG71882.1 - 4.2e-25 88.0 0.7 8.7e-25 87.0 0.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GBG71882.1 - 1.4e-15 57.8 0.3 4.4e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain MCM_OB PF17207.3 GBG71882.1 - 1.4e-14 54.0 0.2 3e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 GBG71882.1 - 6.1e-08 32.3 0.1 5.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GBG71882.1 - 2e-07 31.1 0.1 3.6e-06 27.0 0.0 3.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GBG71882.1 - 0.0027 17.4 0.1 1.4 8.6 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_3 PF07726.11 GBG71882.1 - 0.0055 16.6 0.0 0.015 15.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 GBG71882.1 - 0.017 15.5 0.0 0.051 14.0 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) YhdB PF14148.6 GBG71882.1 - 0.14 12.3 0.3 0.27 11.4 0.3 1.4 1 0 0 1 1 1 0 YhdB-like protein DEAD PF00270.29 GBG71882.1 - 0.15 11.8 0.1 2.8 7.7 0.0 2.7 2 1 1 3 3 3 0 DEAD/DEAH box helicase Polysacc_synt_4 PF04669.13 GBG71883.1 - 6.5e-19 68.2 0.1 1.1e-17 64.3 0.1 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis Presenilin PF01080.17 GBG71884.1 - 1.9 7.2 9.6 3.3 6.4 9.6 1.3 1 1 0 1 1 1 0 Presenilin Integrase_H2C2 PF17921.1 GBG71885.1 - 1.1e-15 57.5 0.1 2.7e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG71885.1 - 8.8e-07 28.7 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG71885.1 - 1.2e-05 25.5 0.0 2.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71885.1 - 0.018 15.3 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Polysacc_syn_2C PF08485.10 GBG71886.1 - 2.4 7.9 6.3 7.6 6.3 0.1 2.6 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein C-terminal Polysacc_synt_4 PF04669.13 GBG71887.1 - 7.9e-17 61.4 0.2 4.4e-15 55.7 0.2 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis K_channel_TID PF07941.11 GBG71887.1 - 0.015 15.7 0.5 0.035 14.5 0.0 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Phage_BR0599 PF09356.10 GBG71887.1 - 0.019 15.3 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 Phage conserved hypothetical protein BR0599 RVT_1 PF00078.27 GBG71888.1 - 1.2e-29 103.4 0.0 2.1e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71888.1 - 1.4e-22 80.0 0.0 2.5e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71888.1 - 1.5e-22 79.5 0.0 3.9e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG71888.1 - 5.3e-07 30.2 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71888.1 - 3.3e-05 23.7 0.0 9.2e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71888.1 - 0.0004 20.9 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG71888.1 - 0.0014 18.8 0.1 0.0049 17.1 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG71888.1 - 0.035 13.9 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease HEAT_2 PF13646.6 GBG71888.1 - 0.15 12.5 0.1 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 HEAT repeats TolA_bind_tri PF16331.5 GBG71888.1 - 8.7 6.5 9.9 0.39 10.8 4.0 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation RVT_1 PF00078.27 GBG71889.1 - 1.2e-29 103.4 0.0 2.1e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71889.1 - 1.3e-22 80.0 0.0 2.4e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71889.1 - 1.5e-22 79.5 0.0 3.9e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG71889.1 - 5.2e-07 30.2 0.0 1.4e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71889.1 - 3.2e-05 23.7 0.0 9.1e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71889.1 - 0.00039 20.9 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG71889.1 - 0.0014 18.8 0.1 0.0048 17.1 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG71889.1 - 0.035 13.9 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease HEAT_2 PF13646.6 GBG71889.1 - 0.14 12.5 0.1 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 HEAT repeats TolA_bind_tri PF16331.5 GBG71889.1 - 8.6 6.5 9.9 0.39 10.8 4.0 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation RVT_1 PF00078.27 GBG71890.1 - 1.2e-18 67.5 0.1 7.5e-17 61.6 0.1 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71890.1 - 4.6e-12 45.9 0.0 4.8e-11 42.6 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG71890.1 - 4.2e-06 26.9 7.2 0.0091 16.2 0.3 4.2 4 1 0 4 4 4 3 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG71890.1 - 0.00043 20.5 0.0 0.0026 18.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase FAM76 PF16046.5 GBG71890.1 - 1.2 8.4 4.5 2.1 7.6 4.5 1.3 1 0 0 1 1 1 0 FAM76 protein Sde2_N_Ubi PF13019.6 GBG71891.1 - 0.023 14.5 0.3 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain ART PF01129.18 GBG71893.1 - 0.22 10.8 4.1 0.38 10.0 4.1 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase OmpH PF03938.14 GBG71893.1 - 0.7 10.2 13.7 1.2 9.5 13.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Gam PF06064.11 GBG71893.1 - 0.75 10.1 4.9 0.47 10.7 1.2 2.3 1 1 1 2 2 2 0 Host-nuclease inhibitor protein Gam RVT_1 PF00078.27 GBG71894.1 - 0.091 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AIM5 PF17050.5 GBG71895.1 - 0.46 11.3 4.6 2.3 9.1 4.6 2.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 FlaC_arch PF05377.11 GBG71895.1 - 3 8.3 20.1 1.5 9.3 1.4 4.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Ist1 PF03398.14 GBG71896.1 - 3.7e-23 82.2 0.1 4.4e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Transferase PF02458.15 GBG71897.1 - 3.6e-62 210.4 0.0 8.5e-60 202.6 0.0 3.7 1 1 0 1 1 1 1 Transferase family BT1 PF03092.16 GBG71898.1 - 7.9 4.6 6.4 10 4.2 6.4 1.1 1 0 0 1 1 1 0 BT1 family Zn_Tnp_IS91 PF14319.6 GBG71899.1 - 0.038 14.0 0.1 0.051 13.6 0.1 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF1561 PF07598.11 GBG71899.1 - 0.075 11.2 0.2 0.089 11.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) RVT_1 PF00078.27 GBG71900.1 - 3.9e-36 124.6 0.1 6.9e-36 123.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71900.1 - 4.2e-30 104.1 0.0 1.1e-29 102.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG71900.1 - 2.5e-29 101.2 0.0 7.1e-29 99.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG71900.1 - 0.039 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Transferase PF02458.15 GBG71901.1 - 1.8e-65 221.3 0.0 3.1e-63 213.9 0.0 3.5 1 1 0 1 1 1 1 Transferase family Transferase PF02458.15 GBG71902.1 - 6.2e-59 199.8 0.0 3.6e-28 98.4 0.1 3.6 2 2 0 2 2 2 2 Transferase family WES_acyltransf PF03007.16 GBG71902.1 - 0.054 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain GIY-YIG PF01541.24 GBG71903.1 - 9.4e-05 22.6 0.1 0.00031 21.0 0.1 2.0 1 0 0 1 1 1 1 GIY-YIG catalytic domain AC_N PF16214.5 GBG71903.1 - 4.9 6.2 6.4 1.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Aldo_ket_red PF00248.21 GBG71904.1 - 1.5e-59 201.7 0.0 1.8e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PPR_2 PF13041.6 GBG71905.1 - 2.8e-33 113.8 5.2 7.1e-08 32.5 0.0 7.5 3 3 5 8 8 8 8 PPR repeat family PPR PF01535.20 GBG71905.1 - 2.7e-32 108.7 17.5 0.0018 18.4 0.1 9.9 10 0 0 10 10 10 8 PPR repeat PPR_3 PF13812.6 GBG71905.1 - 1.4e-22 79.5 0.0 0.0011 18.9 0.0 6.7 4 3 2 7 7 7 4 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG71905.1 - 7.2e-18 64.7 1.8 1.2e-07 31.4 0.0 3.4 3 0 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GBG71905.1 - 4.3e-15 55.1 0.0 0.018 14.7 0.0 8.5 9 0 0 9 9 9 2 PPR repeat TPR_14 PF13428.6 GBG71905.1 - 0.00031 21.3 6.0 0.91 10.5 0.1 5.1 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG71905.1 - 0.0029 17.5 0.1 0.017 15.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG71905.1 - 0.033 14.7 1.3 0.43 11.1 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GBG71905.1 - 0.038 13.9 2.2 9.6 6.1 0.1 3.0 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_10 PF13374.6 GBG71905.1 - 0.043 13.7 1.2 0.21 11.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG71905.1 - 0.096 12.9 1.0 0.55 10.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ESCRT-II PF05871.12 GBG71906.1 - 4.3e-44 150.2 0.0 5.3e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit MMM1 PF10296.9 GBG71906.1 - 0.055 12.5 0.0 0.071 12.1 0.0 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 WD40 PF00400.32 GBG71907.1 - 1.4e-10 41.5 7.6 0.67 10.9 0.2 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG71907.1 - 2.1e-09 37.5 0.1 0.0019 18.4 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Phage_lysozyme PF00959.19 GBG71908.1 - 0.00058 20.3 0.5 0.0071 16.8 0.0 2.8 2 1 1 3 3 3 1 Phage lysozyme NdhM PF10664.9 GBG71908.1 - 0.023 15.0 0.7 0.046 14.0 0.0 1.8 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M Histone PF00125.24 GBG71910.1 - 8.1e-54 181.5 2.0 9.1e-54 181.4 2.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 GBG71910.1 - 0.00017 22.2 2.6 0.00021 21.9 2.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 GBG71910.1 - 0.00035 20.9 0.0 0.00053 20.3 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GBG71910.1 - 0.00067 19.7 0.6 0.001 19.2 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 GBG71910.1 - 0.008 16.2 0.1 0.015 15.3 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 GBG71910.1 - 0.01 16.1 0.1 0.02 15.2 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-CCHC PF00098.23 GBG71911.1 - 5.8e-08 32.5 2.0 1.1e-07 31.5 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle TSC22 PF01166.18 GBG71911.1 - 0.0084 16.4 7.1 0.085 13.2 0.1 3.9 3 1 0 3 3 3 1 TSC-22/dip/bun family zf-ZPR1 PF03367.13 GBG71911.1 - 0.19 11.6 8.8 5.6 6.8 0.0 3.4 2 1 0 2 2 2 0 ZPR1 zinc-finger domain Fzo_mitofusin PF04799.13 GBG71911.1 - 0.19 11.3 12.2 0.35 10.4 0.1 3.1 3 1 0 3 3 3 0 fzo-like conserved region zf-CCHC_4 PF14392.6 GBG71911.1 - 0.23 11.2 1.1 0.5 10.1 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle tRNA-synt_1b PF00579.25 GBG71912.1 - 1.1e-64 218.6 0.0 1.8e-64 217.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 GBG71912.1 - 9.2e-07 28.5 0.3 2.1e-06 27.3 0.3 1.7 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 GBG71912.1 - 0.013 15.3 0.0 0.045 13.5 0.0 1.9 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain PP2C PF00481.21 GBG71913.1 - 5.8e-14 52.4 0.0 9.2e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C RVP_2 PF08284.11 GBG71913.1 - 0.0045 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG71913.1 - 0.035 13.6 0.3 0.056 13.0 0.3 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PP2C PF00481.21 GBG71916.1 - 1.8e-13 50.8 0.0 2.6e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GBG71916.1 - 0.00096 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DsrH PF04077.12 GBG71916.1 - 0.004 17.3 0.0 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 DsrH like protein Med27 PF11571.8 GBG71919.1 - 1.6e-10 41.2 0.4 2e-08 34.5 0.0 2.9 3 0 0 3 3 3 2 Mediator complex subunit 27 Sterol_MT_C PF08498.10 GBG71920.1 - 4.2e-26 91.0 0.8 7.6e-26 90.2 0.8 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GBG71920.1 - 1.2e-15 58.0 0.0 2.6e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG71920.1 - 3.5e-14 52.9 0.0 4.9e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG71920.1 - 4.8e-13 49.6 0.0 1.3e-12 48.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 GBG71920.1 - 1.9e-10 40.5 0.0 2.7e-10 40.0 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GBG71920.1 - 7.4e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG71920.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GBG71920.1 - 0.00014 22.5 0.0 0.00037 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 GBG71920.1 - 0.0025 16.8 0.0 0.0036 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 GBG71920.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 GBG71920.1 - 0.18 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Yip1 PF04893.17 GBG71921.1 - 0.0035 17.1 14.4 0.0053 16.5 14.4 1.4 1 0 0 1 1 1 1 Yip1 domain PHD PF00628.29 GBG71922.1 - 1.1e-09 38.0 8.5 1.1e-09 38.0 8.5 2.8 2 0 0 2 2 2 1 PHD-finger Med4 PF10018.9 GBG71923.1 - 0.066 12.9 2.8 0.086 12.5 2.8 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DivIC PF04977.15 GBG71923.1 - 0.25 11.1 3.4 0.41 10.4 3.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Abhydrolase_6 PF12697.7 GBG71924.1 - 5.6e-17 63.1 0.6 1.2e-16 62.0 0.6 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG71924.1 - 9.7e-17 61.0 0.1 5.1e-16 58.7 0.0 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG71924.1 - 1.7e-13 50.8 0.0 2.9e-11 43.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 GBG71924.1 - 0.00084 19.1 0.1 0.0026 17.4 0.0 1.7 2 0 0 2 2 2 1 Putative esterase UPF0227 PF05728.12 GBG71924.1 - 0.18 11.8 0.1 2.2 8.2 0.1 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) FAM181 PF15238.6 GBG71925.1 - 0.3 10.9 8.0 0.32 10.8 8.0 1.2 1 1 0 1 1 1 0 FAM181 PA26 PF04636.13 GBG71925.1 - 0.84 8.5 6.6 0.96 8.3 6.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TTKRSYEDQ PF10212.9 GBG71925.1 - 1.4 7.8 10.5 1.6 7.7 10.5 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein RVT_1 PF00078.27 GBG71926.1 - 3.4e-26 92.1 0.1 6.8e-26 91.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG71926.1 - 4.8e-21 74.7 0.0 1.6e-20 73.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71926.1 - 3.4e-19 69.1 0.0 1.1e-18 67.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71926.1 - 0.00013 22.0 0.2 0.00032 20.7 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG71926.1 - 0.0021 18.3 0.5 0.023 14.9 0.3 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG71926.1 - 0.0023 17.7 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease ZapB PF06005.12 GBG71926.1 - 0.092 13.2 0.1 0.092 13.2 0.1 3.7 3 1 0 3 3 3 0 Cell division protein ZapB CsgE PF10627.9 GBG71926.1 - 1.4 9.2 4.5 3.5 7.9 4.5 1.7 1 0 0 1 1 1 0 Curli assembly protein CsgE NPV_P10 PF05531.12 GBG71926.1 - 1.7 9.1 5.4 6.3 7.3 1.8 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG71927.1 - 4.8e-19 68.8 0.0 9.4e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG71927.1 - 7.6e-06 25.6 0.1 1.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG71927.1 - 0.004 17.0 0.0 0.03 14.2 0.0 2.6 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Pro_CA PF00484.19 GBG71928.1 - 2.4e-30 105.9 17.7 4e-10 40.2 1.1 5.6 3 3 0 3 3 3 3 Carbonic anhydrase zinc_ribbon_6 PF14599.6 GBG71928.1 - 0.00053 19.9 0.1 11 6.1 0.0 3.7 3 0 0 3 3 3 3 Zinc-ribbon Cuticle_2 PF08184.11 GBG71928.1 - 0.47 10.5 2.4 86 3.3 0.0 3.2 3 0 0 3 3 3 0 Cuticle protein 7 isoform family Pep_deformylase PF01327.21 GBG71929.1 - 1.5e-48 164.4 0.0 2e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase NOA36 PF06524.12 GBG71930.1 - 0.074 12.4 11.5 0.08 12.3 11.5 1.0 1 0 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.12 GBG71930.1 - 0.43 10.4 8.4 0.47 10.2 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 GBG71930.1 - 0.96 7.6 15.0 1.1 7.4 15.0 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 GBG71930.1 - 5.5 6.1 9.4 6 6.0 9.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TRAP_alpha PF03896.16 GBG71932.1 - 0.13 11.5 3.2 0.14 11.3 3.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RPN2_C PF18004.1 GBG71932.1 - 0.2 11.6 2.4 0.23 11.3 2.4 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 GBG71932.1 - 0.29 10.4 3.8 0.39 10.0 3.8 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG71932.1 - 0.31 9.1 12.0 0.33 9.0 12.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 GBG71932.1 - 0.39 10.4 5.5 0.39 10.4 5.1 1.3 1 1 0 1 1 1 0 FAM176 family BUD22 PF09073.10 GBG71932.1 - 0.51 9.6 10.3 0.5 9.7 10.3 1.0 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 GBG71932.1 - 4 6.5 9.2 4.4 6.4 9.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Peptidase_M24 PF00557.24 GBG71933.1 - 7.3e-60 202.2 0.1 9.1e-60 201.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 RINGv PF12906.7 GBG71934.1 - 3.2e-11 43.2 7.4 3.2e-11 43.2 7.4 3.8 3 1 1 4 4 4 1 RING-variant domain PPR_2 PF13041.6 GBG71936.1 - 6.2e-69 228.0 24.3 9e-17 61.0 0.1 11.0 4 4 7 11 11 11 11 PPR repeat family PPR_3 PF13812.6 GBG71936.1 - 2.3e-66 219.8 0.0 1.1e-12 47.8 0.0 7.6 6 1 2 8 8 8 8 Pentatricopeptide repeat domain PPR PF01535.20 GBG71936.1 - 1.7e-48 159.5 47.0 7.6e-08 32.1 0.1 14.3 14 1 0 14 14 14 10 PPR repeat PPR_1 PF12854.7 GBG71936.1 - 1.7e-48 162.0 0.2 2.3e-09 36.8 0.2 12.3 13 0 0 13 13 13 9 PPR repeat PPR_long PF17177.4 GBG71936.1 - 5.2e-24 84.8 5.2 4.3e-06 26.3 0.0 5.1 2 1 3 5 5 5 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GBG71936.1 - 0.0056 17.4 0.4 93 4.3 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG71936.1 - 0.051 14.2 0.1 1.8 9.3 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Prp18 PF02840.15 GBG71936.1 - 0.17 11.9 0.4 0.85 9.7 0.1 2.1 2 0 0 2 2 2 0 Prp18 domain Clathrin PF00637.20 GBG71936.1 - 0.34 10.8 1.7 3.8 7.4 0.1 3.1 4 0 0 4 4 4 0 Region in Clathrin and VPS Vps54_N PF10475.9 GBG71936.1 - 0.58 9.4 2.2 1.5 8.1 0.0 2.6 4 0 0 4 4 4 0 Vacuolar-sorting protein 54, of GARP complex SPX PF03105.19 GBG71936.1 - 0.9 9.4 9.8 1.8 8.4 9.8 1.4 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 GBG71936.1 - 2.3 6.7 7.7 3.6 6.0 7.7 1.2 1 0 0 1 1 1 0 Macoilin family UDG PF03167.19 GBG71937.1 - 2.3e-20 73.1 0.0 4.4e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Dimer_Tnp_hAT PF05699.14 GBG71937.1 - 8.1e-10 38.4 0.3 2.8e-09 36.6 0.3 1.9 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Serglycin PF04360.12 GBG71937.1 - 8.7 6.3 11.8 0.1 12.5 2.2 2.6 3 0 0 3 3 3 0 Serglycin gag-asp_proteas PF13975.6 GBG71939.1 - 5.9e-06 26.8 0.1 2.3e-05 24.9 0.1 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG71939.1 - 0.00012 22.6 0.3 0.00041 20.9 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG71939.1 - 0.00038 20.2 0.1 0.00086 19.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71939.1 - 0.05 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG71939.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DUF1932 PF09130.11 GBG71939.1 - 0.23 11.5 1.5 0.45 10.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) DUF1997 PF09366.10 GBG71941.1 - 1e-35 123.2 0.1 2.1e-32 112.4 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1997) AAA_12 PF13087.6 GBG71942.1 - 1.7e-46 158.4 0.0 2.7e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG71942.1 - 6e-27 95.1 0.0 1.1e-13 51.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GBG71942.1 - 8.9e-09 35.3 0.0 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG71942.1 - 9.3e-08 32.5 0.0 2.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 GBG71942.1 - 5.8e-05 23.2 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2H2_jaz PF12171.8 GBG71942.1 - 0.00077 19.7 3.0 0.66 10.3 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Helicase_RecD PF05127.14 GBG71942.1 - 0.0041 17.0 0.0 0.0095 15.8 0.0 1.7 1 0 0 1 1 1 1 Helicase AAA PF00004.29 GBG71942.1 - 0.015 15.7 0.0 0.041 14.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG71942.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 GBG71942.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain zf-C2H2_2 PF12756.7 GBG71942.1 - 0.021 15.1 1.8 1.7 9.0 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GBG71942.1 - 0.55 11.2 5.8 6.5 7.9 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GBG71942.1 - 0.6 10.7 7.6 1.3 9.6 1.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type SR-25 PF10500.9 GBG71942.1 - 2 7.9 15.4 0.11 12.1 9.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 GBG71943.1 - 7.9e-35 120.4 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG71944.1 - 0.0046 17.0 0.7 0.0084 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF2205 PF10224.9 GBG71944.1 - 0.2 11.7 2.3 0.51 10.4 2.3 1.8 1 1 0 1 1 1 0 Short coiled-coil protein Con-6 PF10346.9 GBG71945.1 - 9.1 6.4 6.6 28 4.8 0.2 2.9 3 0 0 3 3 3 0 Conidiation protein 6 PrgI PF12666.7 GBG71946.1 - 0.31 11.8 1.5 0.95 10.2 0.8 2.0 2 0 0 2 2 2 0 PrgI family protein DUF4131 PF13567.6 GBG71946.1 - 1.1 8.9 9.8 5.2 6.7 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DDE_Tnp_4 PF13359.6 GBG71947.1 - 3.3e-25 88.6 0.3 6.4e-24 84.4 0.0 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71947.1 - 7.3e-11 42.1 0.0 0.00016 21.3 0.0 2.4 1 1 1 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71947.1 - 0.00082 19.1 0.1 0.079 12.6 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain RVT_1 PF00078.27 GBG71949.1 - 2.1e-29 102.6 0.0 3.2e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3410 PF11890.8 GBG71950.1 - 0.062 13.1 0.1 18 5.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3410) Ldl_recept_a PF00057.18 GBG71952.1 - 2.7e-22 78.7 42.8 1.4e-10 41.2 6.4 3.8 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A Pkinase_Tyr PF07714.17 GBG71952.1 - 5e-21 75.1 0.0 9.7e-13 48.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG71952.1 - 1e-19 70.9 0.0 2.6e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Glyco_transf_29 PF00777.18 GBG71952.1 - 0.97 8.8 2.4 1.4 8.2 2.4 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) RT_RNaseH_2 PF17919.1 GBG71953.1 - 1.7e-28 98.6 0.0 2.8e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71953.1 - 3e-26 91.7 0.0 5.2e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71953.1 - 4.8e-16 59.0 0.0 7.2e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG71953.1 - 0.04 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Vfa1 PF08432.10 GBG71953.1 - 0.14 12.5 3.0 0.21 11.9 3.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 GBG71953.1 - 3.9 5.6 8.6 5.4 5.2 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG71953.1 - 4.2 6.7 12.9 6.6 6.1 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Chromo PF00385.24 GBG71957.1 - 1.9e-11 43.7 0.0 3.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG71957.1 - 3e-10 40.3 0.0 8.1e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Tau95_N PF17682.1 GBG71958.1 - 0.28 11.4 1.7 0.53 10.5 1.7 1.4 1 0 0 1 1 1 0 Tau95 Triple barrel domain FAM176 PF14851.6 GBG71958.1 - 0.71 9.5 8.1 0.6 9.8 4.3 2.0 2 0 0 2 2 2 0 FAM176 family Connexin PF00029.19 GBG71958.1 - 1.7 8.3 3.0 1.7 8.4 1.8 1.5 2 0 0 2 2 2 0 Connexin Eapp_C PF10238.9 GBG71958.1 - 2.1 8.4 7.2 0.22 11.6 2.6 1.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein HTH_48 PF17906.1 GBG71959.1 - 0.052 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase UCH PF00443.29 GBG71960.1 - 6.8e-53 179.8 0.1 1e-52 179.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG71960.1 - 1.9e-25 90.1 0.3 2.7e-25 89.6 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2175 PF09943.9 GBG71960.1 - 0.1 12.9 0.2 0.51 10.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) POLO_box PF00659.18 GBG71961.1 - 6.3e-20 71.1 0.0 5.6e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Pkinase PF00069.25 GBG71961.1 - 0.00011 21.7 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71961.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4524 PF15025.6 GBG71961.1 - 0.2 11.4 5.8 0.23 11.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4524) SelP_N PF04592.14 GBG71961.1 - 8.1 5.8 12.4 29 4.0 12.4 1.9 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pkinase PF00069.25 GBG71962.1 - 2.1e-37 128.9 0.1 2.6e-37 128.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG71962.1 - 2.6e-23 82.6 0.1 3.7e-23 82.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG71962.1 - 2.1e-06 27.3 0.0 0.0015 17.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 GBG71962.1 - 0.1 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.27 GBG71963.1 - 6.3e-10 38.9 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Topo_Zn_Ribbon PF08272.11 GBG71963.1 - 0.015 14.9 0.3 0.035 13.8 0.3 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DUF2682 PF10909.8 GBG71964.1 - 1.3 9.6 5.9 19 5.8 0.1 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2682) Adaptin_N PF01602.20 GBG71965.1 - 7.8e-157 523.0 20.5 1.1e-156 522.5 20.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GBG71965.1 - 1.9e-65 219.9 3.1 1.9e-65 219.9 3.1 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 GBG71965.1 - 2.1e-24 85.8 0.0 4.8e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 GBG71965.1 - 2e-16 60.2 8.4 9.3e-08 32.4 0.2 5.8 3 2 3 6 6 5 4 HEAT repeats HEAT PF02985.22 GBG71965.1 - 6.5e-12 44.6 2.5 0.0021 18.2 0.1 5.2 4 0 0 4 4 4 3 HEAT repeat Alpha_adaptinC2 PF02883.20 GBG71965.1 - 7.1e-06 26.3 0.1 1.5e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd3 PF12719.7 GBG71965.1 - 0.00082 18.7 4.5 0.0031 16.7 0.0 3.2 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain Arm_2 PF04826.13 GBG71965.1 - 0.0012 18.4 1.6 0.022 14.2 0.0 2.5 1 1 1 2 2 2 1 Armadillo-like HEAT_EZ PF13513.6 GBG71965.1 - 0.0015 19.0 7.2 1 9.9 0.0 6.0 6 0 0 6 6 5 1 HEAT-like repeat RTP1_C1 PF10363.9 GBG71965.1 - 0.0018 18.5 4.8 0.13 12.4 0.0 4.5 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 GBG71965.1 - 0.0074 15.9 2.5 12 5.4 0.0 3.7 2 1 1 3 3 3 0 CLASP N terminal Arm PF00514.23 GBG71965.1 - 0.019 15.0 2.4 2.9 8.1 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 GBG71965.1 - 0.023 14.1 6.5 0.43 9.9 1.4 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5578) Atx10homo_assoc PF09759.9 GBG71965.1 - 0.031 14.3 4.4 1.6 8.8 0.1 3.8 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 GBG71965.1 - 0.079 12.9 4.4 2.2 8.2 0.5 3.9 3 2 0 3 3 3 0 Myosin-binding striated muscle assembly central PEP-utilisers_N PF05524.13 GBG71965.1 - 0.11 12.7 0.0 0.46 10.7 0.0 2.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal ANAPC3 PF12895.7 GBG71965.1 - 0.32 11.2 2.9 0.59 10.4 0.0 2.8 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec7_N PF12783.7 GBG71965.1 - 0.66 9.9 9.5 0.041 13.8 1.4 3.1 4 2 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Glyco_transf_34 PF05637.12 GBG71966.1 - 4e-30 105.3 0.5 1.1e-29 103.9 0.5 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family FdsD PF11390.8 GBG71966.1 - 0.067 13.5 0.4 8.8 6.7 0.0 2.6 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD Chlorophyllase2 PF12740.7 GBG71967.1 - 1.1e-21 76.9 0.0 1.1e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 GBG71967.1 - 1.3e-14 54.0 0.0 1.9e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_6 PF12697.7 GBG71967.1 - 1.4e-09 38.9 0.1 2.9e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 GBG71967.1 - 3.4e-06 25.8 0.0 0.054 12.0 0.0 2.7 3 0 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 GBG71967.1 - 0.0071 15.6 0.0 0.018 14.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 GBG71967.1 - 0.019 14.8 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 GBG71967.1 - 0.039 12.6 1.1 0.039 12.6 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 GBG71967.1 - 0.043 13.4 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 GBG71967.1 - 0.17 11.5 0.0 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold RT_RNaseH_2 PF17919.1 GBG71968.1 - 1.5e-29 102.0 0.0 3.9e-29 100.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG71968.1 - 6.2e-29 101.1 0.1 1.3e-28 100.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG71968.1 - 2.2e-25 89.0 0.0 4.3e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG71968.1 - 9.4e-16 57.7 0.0 3.6e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG71968.1 - 4.3e-15 56.0 0.0 8.8e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG71968.1 - 0.00078 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG71968.1 - 0.13 12.0 0.0 0.43 10.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain DBR1 PF05011.13 GBG71969.1 - 2.8e-34 118.5 0.0 4.4e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 GBG71969.1 - 5.9e-09 36.7 1.0 9.4e-09 36.1 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GBG71969.1 - 0.00016 21.9 0.0 0.00024 21.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-CCHC PF00098.23 GBG71970.1 - 1.4e-05 24.9 2.9 2.9e-05 23.9 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle HA2 PF04408.23 GBG71970.1 - 0.16 12.2 0.9 0.51 10.6 0.9 1.8 1 0 0 1 1 1 0 Helicase associated domain (HA2) Thioredoxin_4 PF13462.6 GBG71972.1 - 1.3e-13 51.4 0.0 1.6e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 GBG71972.1 - 2.4e-10 40.5 0.0 9e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Fer2_3 PF13085.6 GBG71972.1 - 0.0007 19.6 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Thioredoxin_5 PF13743.6 GBG71972.1 - 0.0057 16.4 0.1 0.043 13.5 0.0 1.9 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 GBG71972.1 - 0.23 11.5 0.0 9.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Retrotrans_gag PF03732.17 GBG71973.1 - 0.00023 21.4 0.3 0.00097 19.4 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG71974.1 - 1.4e-09 38.4 0.0 2.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71974.1 - 8.2e-09 35.3 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG71974.1 - 1.3e-07 32.1 0.0 3.2e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG71974.1 - 5.7e-05 22.9 0.0 9.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Vps39_2 PF10367.9 GBG71975.1 - 4.1e-20 72.3 0.1 1.1e-19 70.8 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 GBG71975.1 - 1.2e-15 57.7 0.0 1.9e-10 40.8 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Vps39_1 PF10366.9 GBG71975.1 - 4.7e-08 33.3 0.0 7.5e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 1 Paired_CXXCH_1 PF09699.10 GBG71975.1 - 0.058 13.2 0.5 0.12 12.1 0.5 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) HA2 PF04408.23 GBG71976.1 - 6.8e-26 90.7 0.1 1.4e-25 89.6 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GBG71976.1 - 3.2e-20 72.3 0.0 8.7e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GBG71976.1 - 3.2e-12 46.8 0.0 2.7e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GBG71976.1 - 1.2e-07 31.7 0.1 2.6e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GBG71976.1 - 2.7e-07 31.0 0.0 1.2e-06 28.8 0.1 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 GBG71976.1 - 3e-05 24.4 0.1 7.4e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG71976.1 - 9.1e-05 22.3 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 GBG71976.1 - 0.0022 18.0 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 GBG71976.1 - 0.0022 17.6 0.1 0.0065 16.1 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 GBG71976.1 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain IstB_IS21 PF01695.17 GBG71976.1 - 0.0072 16.1 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF2075 PF09848.9 GBG71976.1 - 0.0086 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 GBG71976.1 - 0.012 16.1 0.4 0.2 12.2 0.4 2.3 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.16 GBG71976.1 - 0.025 14.1 2.4 0.037 13.5 0.4 2.3 2 1 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 GBG71976.1 - 0.033 13.2 0.0 0.076 12.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 GBG71976.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 GBG71976.1 - 0.18 11.8 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CENP-B_dimeris PF09026.10 GBG71976.1 - 1.3 9.5 8.2 3.2 8.2 8.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Mito_carr PF00153.27 GBG71977.1 - 1.5e-58 194.7 1.8 2.6e-20 72.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF824 PF05688.11 GBG71977.1 - 0.027 14.3 0.1 0.55 10.1 0.0 2.6 2 1 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) PALP PF00291.25 GBG71978.1 - 3.4e-71 240.0 7.0 4.7e-70 236.3 7.0 2.2 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 GBG71978.1 - 1.5e-48 162.5 0.0 2.5e-24 84.8 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase NST1 PF13945.6 GBG71979.1 - 0.89 9.6 17.6 1.4 9.0 17.6 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator tRNA-synt_2b PF00587.25 GBG71980.1 - 1.1e-26 93.9 0.0 6e-25 88.3 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GBG71980.1 - 4.2e-16 59.1 6.8 7.9e-16 58.2 6.8 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4400 PF14348.6 GBG71980.1 - 0.094 12.2 0.4 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Baculo_PEP_C PF04513.12 GBG71980.1 - 0.13 12.3 1.0 0.22 11.6 1.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 GBG71980.1 - 0.26 11.8 1.0 0.48 10.9 1.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein eIF3_N PF09440.10 GBG71980.1 - 0.34 11.4 2.4 0.95 9.9 2.4 1.7 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain APG6_N PF17675.1 GBG71980.1 - 0.77 10.3 6.7 2.4 8.7 6.7 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Peptidase_S64 PF08192.11 GBG71980.1 - 0.83 8.1 5.5 1.5 7.2 5.5 1.3 1 0 0 1 1 1 0 Peptidase family S64 ERM PF00769.19 GBG71980.1 - 1.9 8.3 8.6 0.063 13.1 2.5 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RRM_1 PF00076.22 GBG71981.1 - 7.1e-16 57.8 0.0 8.9e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dimer_Tnp_hAT PF05699.14 GBG71982.1 - 2e-05 24.3 0.0 4.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ParcG PF10274.9 GBG71982.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Parkin co-regulated protein DDE_Tnp_4 PF13359.6 GBG71983.1 - 2.6e-30 105.2 0.0 4.5e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71983.1 - 5.2e-12 45.8 0.0 8.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71983.1 - 0.00039 20.1 0.2 0.74 9.4 0.3 2.3 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG71983.1 - 0.015 15.7 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG71984.1 - 8.6e-09 35.7 0.3 2e-08 34.5 0.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG71984.1 - 0.19 12.1 0.2 0.4 11.0 0.2 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-CCHC PF00098.23 GBG71985.1 - 0.019 15.0 1.9 0.032 14.3 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase_Tyr PF07714.17 GBG71986.1 - 2.8e-58 197.2 0.0 3.5e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG71986.1 - 1.1e-49 169.2 0.0 1.5e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 GBG71986.1 - 0.032 13.2 0.1 0.051 12.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DEC-1_N PF04625.13 GBG71986.1 - 6.7 5.6 8.4 11 5.0 8.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Myb_DNA-bind_4 PF13837.6 GBG71987.1 - 0.00093 19.5 4.9 0.0018 18.6 4.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG71988.1 - 2.1e-27 95.7 0.0 3.7e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG71988.1 - 1.4e-09 37.9 0.0 2.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG71988.1 - 0.0049 16.6 1.2 0.031 13.9 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain DUF2694 PF10904.8 GBG71988.1 - 0.092 12.8 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) Malectin_like PF12819.7 GBG71989.1 - 3.5e-94 315.7 0.0 2e-52 178.4 0.0 2.1 2 0 0 2 2 2 2 Malectin-like domain Malectin PF11721.8 GBG71989.1 - 7.6e-38 130.2 0.0 1.3e-14 54.7 0.0 4.3 4 0 0 4 4 4 3 Malectin domain LRR_8 PF13855.6 GBG71989.1 - 5.7e-11 42.0 10.0 8.4e-07 28.7 1.4 1.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GBG71989.1 - 2e-08 34.4 2.5 2e-08 34.4 2.5 2.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG71989.1 - 9.3e-05 22.5 2.4 0.31 11.7 0.3 3.2 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_6 PF13516.6 GBG71989.1 - 0.00017 21.4 4.6 0.022 14.8 0.2 2.9 2 0 0 2 2 2 2 Leucine Rich repeat Methyltransf_12 PF08242.12 GBG71991.1 - 0.3 11.8 2.1 2.4 8.9 0.0 3.0 2 1 1 3 3 3 0 Methyltransferase domain DUF4085 PF13315.6 GBG71991.1 - 2.6 7.6 7.6 11 5.6 3.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4085) DUF3006 PF11213.8 GBG71992.1 - 0.014 15.6 2.1 0.03 14.5 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Rep_fac_C PF08542.11 GBG71993.1 - 1.2e-25 89.7 0.0 2.8e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 GBG71993.1 - 1.2e-14 54.8 0.1 1.8e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GBG71993.1 - 1.6e-12 47.5 0.0 7.5e-10 38.8 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 GBG71993.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GBG71993.1 - 0.00014 21.3 0.0 0.0021 17.5 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 GBG71993.1 - 0.00016 21.5 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GBG71993.1 - 0.00018 21.8 0.1 0.071 13.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 GBG71993.1 - 0.00021 21.3 0.0 0.00072 19.5 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 GBG71993.1 - 0.00028 21.3 0.0 0.0073 16.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GBG71993.1 - 0.00084 19.1 0.0 0.0018 18.1 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 GBG71993.1 - 0.00086 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF5119 PF17145.4 GBG71993.1 - 0.0042 17.1 0.0 2.7 7.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5119) AAA_25 PF13481.6 GBG71993.1 - 0.0043 16.6 0.0 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GBG71993.1 - 0.005 17.4 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 GBG71993.1 - 0.0058 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GBG71993.1 - 0.0059 16.1 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 GBG71993.1 - 0.0063 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 GBG71993.1 - 0.0067 16.8 0.1 0.016 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GBG71993.1 - 0.0072 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 GBG71993.1 - 0.0084 16.4 0.0 0.025 14.9 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain TniB PF05621.11 GBG71993.1 - 0.014 14.8 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 GBG71993.1 - 0.017 14.9 0.1 0.041 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 GBG71993.1 - 0.025 13.6 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 GBG71993.1 - 0.034 14.4 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GBG71993.1 - 0.037 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 GBG71993.1 - 0.049 14.2 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 GBG71993.1 - 0.091 13.2 0.0 0.22 12.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase MipZ PF09140.11 GBG71993.1 - 0.095 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ T2SSE PF00437.20 GBG71993.1 - 0.097 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 GBG71993.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 GBG71993.1 - 0.22 10.7 0.1 3 7.0 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zf-CCHC PF00098.23 GBG71994.1 - 0.098 12.8 0.3 0.23 11.6 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Transferase PF02458.15 GBG71994.1 - 0.17 10.5 2.5 1.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Transferase family OmpH PF03938.14 GBG71994.1 - 2.7 8.3 20.6 0.25 11.7 6.3 3.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF4522 PF15022.6 GBG71994.1 - 4 7.7 8.0 2.2 8.6 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) RT_RNaseH_2 PF17919.1 GBG71995.1 - 1e-29 102.5 0.1 2e-29 101.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG71995.1 - 1.1e-26 93.2 0.2 2.3e-26 92.1 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG71995.1 - 0.0024 18.0 0.1 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG71995.1 - 0.0076 16.1 0.2 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG71995.1 - 0.018 14.7 0.7 0.099 12.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Peptidase_C39 PF03412.15 GBG71995.1 - 0.028 14.2 0.1 0.078 12.8 0.1 1.8 1 0 0 1 1 1 0 Peptidase C39 family DUF2862 PF11061.8 GBG71995.1 - 0.056 13.3 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) Asp_protease_2 PF13650.6 GBG71996.1 - 3.1e-08 34.1 0.0 9.3e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG71996.1 - 2.2e-07 31.4 0.0 6.1e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG71996.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG71996.1 - 0.00023 21.0 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease HIP1_clath_bdg PF16515.5 GBG71996.1 - 0.014 16.0 6.6 0.014 16.0 6.6 3.0 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4596 PF15363.6 GBG71996.1 - 0.18 12.0 1.8 0.68 10.2 1.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) NPV_P10 PF05531.12 GBG71996.1 - 0.44 11.0 2.9 0.58 10.7 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GBG71996.1 - 0.46 9.8 14.9 0.37 10.1 6.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DOG1 PF14144.6 GBG71997.1 - 1.3e-33 115.1 0.0 3.8e-33 113.5 0.0 1.9 1 0 0 1 1 1 1 Seed dormancy control bZIP_1 PF00170.21 GBG71997.1 - 5.5e-07 29.6 12.8 1.1e-06 28.6 12.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG71997.1 - 2.5e-06 27.5 13.2 5.6e-06 26.4 13.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Tape_meas_lam_C PF09718.10 GBG71997.1 - 0.028 14.5 1.3 0.082 13.0 1.3 1.7 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) MLTR_LBD PF17765.1 GBG71997.1 - 0.09 12.9 2.5 0.11 12.6 0.1 2.3 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain Baculo_gp41 PF04700.12 GBG71997.1 - 0.21 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region DOG1 PF14144.6 GBG71998.1 - 1.3e-33 115.1 0.0 3.9e-33 113.5 0.0 1.9 1 0 0 1 1 1 1 Seed dormancy control bZIP_1 PF00170.21 GBG71998.1 - 5.6e-07 29.6 12.8 1.1e-06 28.6 12.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG71998.1 - 2.5e-06 27.5 13.2 5.6e-06 26.3 13.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Tape_meas_lam_C PF09718.10 GBG71998.1 - 0.023 14.8 1.3 0.083 13.0 1.3 1.9 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) MLTR_LBD PF17765.1 GBG71998.1 - 0.092 12.9 2.5 0.11 12.6 0.1 2.3 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain Baculo_gp41 PF04700.12 GBG71998.1 - 0.21 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region DOG1 PF14144.6 GBG71999.1 - 1.2e-33 115.1 0.0 3.6e-33 113.6 0.0 1.9 1 0 0 1 1 1 1 Seed dormancy control bZIP_1 PF00170.21 GBG71999.1 - 5.3e-07 29.6 12.8 1.1e-06 28.7 12.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG71999.1 - 2.3e-06 27.6 13.2 5.3e-06 26.4 13.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Tape_meas_lam_C PF09718.10 GBG71999.1 - 0.022 14.9 1.3 0.079 13.1 1.3 1.9 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) MLTR_LBD PF17765.1 GBG71999.1 - 0.063 13.4 2.1 0.11 12.7 0.1 2.4 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain Baculo_gp41 PF04700.12 GBG71999.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region DOG1 PF14144.6 GBG72000.1 - 8.3e-34 115.6 0.0 2.7e-33 114.0 0.0 2.0 1 0 0 1 1 1 1 Seed dormancy control bZIP_1 PF00170.21 GBG72000.1 - 4.1e-07 30.0 12.8 8.3e-07 29.0 12.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG72000.1 - 2e-06 27.8 13.2 4.1e-06 26.8 13.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Tape_meas_lam_C PF09718.10 GBG72000.1 - 0.016 15.4 1.3 0.061 13.5 1.3 2.0 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) MLTR_LBD PF17765.1 GBG72000.1 - 0.06 13.5 2.5 0.08 13.1 0.1 2.3 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain Baculo_gp41 PF04700.12 GBG72000.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region TetR_C_29 PF17938.1 GBG72000.1 - 0.15 12.1 0.2 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain 2Fe-2S_thioredx PF01257.19 GBG72002.1 - 6.8e-56 188.2 0.0 9.2e-56 187.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.11 GBG72002.1 - 0.022 15.2 0.0 0.083 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) zf-CCHC PF00098.23 GBG72003.1 - 1e-05 25.4 3.9 2.8e-05 24.0 3.9 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG72003.1 - 0.015 15.1 2.5 0.032 14.1 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Eapp_C PF10238.9 GBG72003.1 - 0.058 13.5 0.1 0.058 13.5 0.1 3.0 2 1 0 2 2 2 0 E2F-associated phosphoprotein SLC12 PF03522.15 GBG72003.1 - 0.37 9.8 10.5 0.52 9.3 10.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 FliL PF03748.14 GBG72003.1 - 0.83 10.3 5.2 1.7 9.2 5.2 1.6 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL YjbH PF06082.11 GBG72003.1 - 1.2 7.9 5.0 1.6 7.5 5.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH PFL-like PF02901.15 GBG72003.1 - 1.3 7.6 9.7 1.8 7.1 9.7 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like CAF1 PF04857.20 GBG72003.1 - 4.8 6.3 7.6 7 5.7 7.6 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease RNA_pol_Rpc4 PF05132.14 GBG72003.1 - 4.8 7.6 13.3 17 5.8 8.1 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 gag-asp_proteas PF13975.6 GBG72004.1 - 1.6e-07 31.7 0.0 3.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72004.1 - 2.3e-05 25.0 0.0 4.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG72004.1 - 0.00092 19.0 0.4 0.0016 18.3 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG72004.1 - 0.019 15.3 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_5 PF14787.6 GBG72004.1 - 0.044 13.5 0.2 0.096 12.4 0.2 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SICA_C PF12879.7 GBG72004.1 - 0.19 11.7 2.3 0.67 10.0 2.3 2.0 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain RT_RNaseH_2 PF17919.1 GBG72005.1 - 2.9e-25 88.2 0.0 5.2e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72005.1 - 1.7e-22 79.7 0.0 3.5e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72005.1 - 2.1e-14 53.6 0.1 3.2e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG72005.1 - 0.16 10.2 10.0 0.2 9.8 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG72005.1 - 0.56 9.6 11.8 0.79 9.1 11.8 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG72005.1 - 1.3 7.3 8.4 1.7 6.8 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG72005.1 - 1.8 8.2 10.4 2.9 7.6 10.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RT_RNaseH_2 PF17919.1 GBG72006.1 - 2.2e-27 95.0 0.0 2.2e-26 91.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72006.1 - 2.8e-22 79.0 0.0 9.3e-22 77.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72006.1 - 4.1e-22 78.8 0.0 7.6e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG72006.1 - 9.9e-09 34.9 1.5 2.5e-08 33.6 1.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG72006.1 - 0.00033 20.4 2.0 0.00075 19.3 2.0 1.7 1 0 0 1 1 1 1 Zinc knuckle ADH_zinc_N PF00107.26 GBG72007.1 - 2.6e-22 79.2 0.0 4.2e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GBG72007.1 - 1e-18 68.7 0.0 1.7e-18 68.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GBG72007.1 - 5.9e-08 32.6 0.1 2.1e-07 30.8 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GBG72007.1 - 0.02 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Gly_rich_SFCGS PF14272.6 GBG72007.1 - 0.31 11.1 4.3 0.19 11.8 0.3 2.5 3 0 0 3 3 3 0 Glycine-rich SFCGS ADH_zinc_N PF00107.26 GBG72008.1 - 3e-18 66.0 0.0 5.4e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GBG72008.1 - 7.4e-15 56.2 0.0 1.4e-14 55.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GBG72008.1 - 1.4e-09 37.8 0.0 3.8e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GBG72008.1 - 0.088 12.7 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Gly_rich_SFCGS PF14272.6 GBG72008.1 - 0.21 11.6 2.7 0.16 12.0 0.2 2.1 2 1 0 2 2 2 0 Glycine-rich SFCGS EF-hand_1 PF00036.32 GBG72009.1 - 4.8e-08 32.0 0.5 6.3e-08 31.6 0.5 1.2 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 GBG72009.1 - 1.3e-07 30.7 1.2 2e-07 30.2 1.2 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GBG72009.1 - 1.2e-06 28.0 0.2 1.6e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GBG72009.1 - 1.5e-06 28.5 0.1 2e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GBG72009.1 - 1.1e-05 25.1 0.1 1.5e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 GBG72009.1 - 0.053 13.5 0.3 0.064 13.2 0.3 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand AAA PF00004.29 GBG72010.1 - 2.4e-30 105.7 0.0 4.5e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 GBG72010.1 - 6.1e-23 81.7 0.0 1.4e-22 80.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 GBG72010.1 - 1.3e-16 60.1 0.8 1.2e-15 57.0 0.1 2.8 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 GBG72010.1 - 3.6e-05 23.6 0.0 7.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GBG72010.1 - 0.00066 19.7 0.0 0.0038 17.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GBG72010.1 - 0.0025 17.9 0.1 0.0079 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 GBG72010.1 - 0.0035 16.6 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_17 PF13207.6 GBG72010.1 - 0.0042 17.5 0.6 0.1 13.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GBG72010.1 - 0.0048 17.3 1.8 0.22 11.9 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain TsaE PF02367.17 GBG72010.1 - 0.011 15.7 0.4 0.56 10.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GBG72010.1 - 0.015 15.4 0.0 0.051 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GBG72010.1 - 0.023 15.0 0.2 0.68 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG72010.1 - 0.046 13.3 0.1 0.94 9.0 0.0 2.7 1 1 1 2 2 2 0 AAA domain P53 PF00870.18 GBG72010.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P53 DNA-binding domain IstB_IS21 PF01695.17 GBG72010.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 GBG72010.1 - 0.11 11.8 0.1 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 GBG72010.1 - 0.13 11.6 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GBG72010.1 - 0.23 11.9 0.0 0.5 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TFIIE-A_C PF11521.8 GBG72010.1 - 0.51 10.7 7.5 1.4 9.2 7.5 1.7 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha SR-25 PF10500.9 GBG72010.1 - 7.8 6.0 10.5 25 4.4 10.5 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SAP PF02037.27 GBG72012.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 SAP domain Phage_endo_I PF05367.11 GBG72014.1 - 0.079 12.6 0.1 2.5 7.7 0.0 2.8 3 0 0 3 3 3 0 Phage endonuclease I CH PF00307.31 GBG72015.1 - 2.6e-20 72.6 0.0 0.00013 22.1 0.0 5.3 5 0 0 5 5 5 5 Calponin homology (CH) domain Myc_N PF01056.18 GBG72015.1 - 0.001 19.0 4.6 0.001 19.0 4.6 7.1 5 1 0 6 6 6 2 Myc amino-terminal region DDE_Tnp_4 PF13359.6 GBG72017.1 - 5.2e-24 84.7 0.1 2.1e-23 82.8 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72017.1 - 3.3e-11 43.2 0.0 5.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72017.1 - 0.00018 21.3 0.3 0.0029 17.3 0.0 2.5 3 0 0 3 3 3 1 Transposase DDE domain Stm1_N PF09598.10 GBG72018.1 - 0.12 13.2 0.6 0.12 13.2 0.6 2.1 2 0 0 2 2 2 0 Stm1 NPV_P10 PF05531.12 GBG72020.1 - 0.0088 16.5 22.1 8.3 7.0 0.8 6.7 6 2 1 7 7 7 3 Nucleopolyhedrovirus P10 protein LPP PF04728.13 GBG72020.1 - 0.02 15.3 1.1 0.02 15.3 1.1 8.4 9 1 0 9 9 9 0 Lipoprotein leucine-zipper HsbA PF12296.8 GBG72020.1 - 0.14 12.6 6.9 0.52 10.8 1.2 3.4 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Laminin_II PF06009.12 GBG72020.1 - 0.72 9.9 75.0 0.3 11.1 9.8 6.5 1 1 4 6 6 6 0 Laminin Domain II Myb_DNA-bind_4 PF13837.6 GBG72021.1 - 0.0052 17.1 1.5 0.0052 17.1 1.5 2.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Ctr PF04145.15 GBG72021.1 - 0.14 12.8 1.1 0.24 12.0 0.1 2.0 2 0 0 2 2 2 0 Ctr copper transporter family RT_RNaseH_2 PF17919.1 GBG72022.1 - 4.6e-23 81.1 0.0 7.6e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72022.1 - 1.8e-20 73.2 0.0 3.9e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72022.1 - 4.2e-10 39.5 0.0 6.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG72022.1 - 0.09 12.1 18.8 0.12 11.6 18.8 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG72022.1 - 3.6 6.9 18.9 5.5 6.3 18.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG72022.1 - 4.2 5.5 18.5 5.7 5.0 18.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG72022.1 - 6.5 4.9 16.7 8.9 4.5 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein MSA-2c PF12238.8 GBG72022.1 - 8.1 6.4 6.9 19 5.2 6.9 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c DEK_C PF08766.11 GBG72023.1 - 0.0083 16.0 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain RVT_1 PF00078.27 GBG72024.1 - 8.7e-30 103.9 0.1 1.4e-29 103.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72024.1 - 4.6e-22 77.9 0.0 1.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72024.1 - 6.7e-22 77.8 0.0 2.2e-21 76.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase XPG_I PF00867.18 GBG72024.1 - 4.9e-18 65.3 0.0 1.1e-14 54.6 0.0 3.0 2 0 0 2 2 2 2 XPG I-region XPG_N PF00752.17 GBG72024.1 - 7.9e-16 58.4 0.0 1.8e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 GBG72024.1 - 1.3e-05 24.8 0.0 3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 GBG72024.1 - 0.0033 17.4 0.5 0.01 15.9 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Retrotrans_gag PF03732.17 GBG72024.1 - 0.0045 17.2 0.6 0.0045 17.2 0.6 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein PaaX_C PF08223.11 GBG72024.1 - 0.032 14.5 0.0 0.22 11.8 0.0 2.5 1 1 1 2 2 2 0 PaaX-like protein C-terminal domain TPR_1 PF00515.28 GBG72024.1 - 0.039 13.8 0.3 0.12 12.3 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Epimerase PF01370.21 GBG72025.1 - 1.2e-36 126.4 0.0 5e-31 108.0 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GBG72025.1 - 1e-35 123.7 0.0 2.1e-28 99.7 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GBG72025.1 - 3.5e-16 59.0 0.0 7.8e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GBG72025.1 - 5.9e-13 48.6 0.0 1.6e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GBG72025.1 - 1e-10 41.3 0.0 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 GBG72025.1 - 8.9e-09 35.5 0.1 8.9e-09 35.5 0.1 1.9 2 0 0 2 2 1 1 KR domain RmlD_sub_bind PF04321.17 GBG72025.1 - 9.3e-08 31.5 0.3 2.5e-07 30.1 0.2 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 GBG72025.1 - 1.8e-06 27.5 1.0 3.5e-06 26.6 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 GBG72025.1 - 0.00084 19.3 0.7 0.0051 16.7 0.7 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Pyr_redox_2 PF07992.14 GBG72025.1 - 0.005 16.1 0.1 0.0082 15.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GBG72025.1 - 0.027 14.3 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GBG72025.1 - 0.057 14.0 0.1 0.15 12.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SR-25 PF10500.9 GBG72025.1 - 1.4 8.5 15.8 2.5 7.7 15.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LIAS_N PF16881.5 GBG72026.1 - 3.8e-18 65.9 0.0 7e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 GBG72026.1 - 8.1e-13 49.1 0.0 2e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily RT_RNaseH PF17917.1 GBG72027.1 - 1.1e-20 73.9 0.0 1.8e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72027.1 - 6.4e-19 67.9 0.0 1.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72027.1 - 6.8e-10 38.9 0.0 1.7e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG72028.1 - 1.9e-21 76.3 0.0 6.4e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72028.1 - 1.8e-19 69.6 0.0 7.3e-19 67.7 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72028.1 - 2e-13 50.6 0.0 1e-12 48.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG72028.1 - 3.5e-12 46.2 0.0 1e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG72028.1 - 1.5e-07 31.9 0.0 3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72028.1 - 3.8e-05 24.2 0.0 7.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG72028.1 - 0.04 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 GBG72028.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG72029.1 - 8.8e-22 77.4 0.0 2.8e-21 75.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72029.1 - 1e-19 70.4 0.0 3.3e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72029.1 - 1.4e-13 51.0 0.0 4.4e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG72029.1 - 1.9e-12 47.1 0.0 4.8e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG72029.1 - 0.026 14.8 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Inositol_P PF00459.25 GBG72030.1 - 3.1e-50 171.2 0.0 4e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Mg_trans_NIPA PF05653.14 GBG72031.1 - 1.8e-135 450.8 17.9 2e-135 450.6 17.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GBG72031.1 - 0.00013 22.1 7.1 0.00013 22.1 7.1 4.0 2 2 2 4 4 4 2 EamA-like transporter family zf-CCHC PF00098.23 GBG72032.1 - 9.8e-06 25.4 1.6 9.8e-06 25.4 1.6 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG72032.1 - 0.044 13.5 0.7 0.11 12.3 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle RR_TM4-6 PF06459.12 GBG72032.1 - 0.31 10.8 6.5 6.1 6.6 9.6 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peptidase_S26 PF10502.9 GBG72033.1 - 0.0011 18.7 0.0 0.12 12.1 0.0 2.1 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DHQ_synthase PF01761.20 GBG72034.1 - 2.7e-105 351.3 0.0 3.8e-105 350.8 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Peptidase_M22 PF00814.25 GBG72034.1 - 2.8e-72 243.7 0.0 4.2e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family Fe-ADH_2 PF13685.6 GBG72034.1 - 1.9e-11 44.2 0.1 7e-11 42.3 0.1 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 GBG72034.1 - 4.6e-05 22.4 0.3 0.00023 20.1 0.1 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Ammonium_transp PF00909.21 GBG72035.1 - 2.9e-125 418.1 26.8 3.6e-125 417.8 26.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Nop14 PF04147.12 GBG72037.1 - 0.63 8.2 8.4 0.68 8.1 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG72037.1 - 0.89 8.9 9.8 1.1 8.6 9.8 1.1 1 0 0 1 1 1 0 SDA1 RT_RNaseH_2 PF17919.1 GBG72038.1 - 1.2e-21 76.6 0.0 2.4e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72038.1 - 1.2e-19 70.5 0.0 3.3e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72038.1 - 4.6e-10 39.7 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG72038.1 - 0.0004 20.0 0.0 0.0008 19.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG72038.1 - 0.15 11.9 0.0 0.53 10.1 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Peptidase_C1 PF00112.23 GBG72039.1 - 5e-74 249.1 0.2 6.6e-74 248.7 0.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GBG72039.1 - 2.7e-14 53.4 2.7 4e-14 52.8 2.7 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GBG72039.1 - 9.9e-08 31.2 0.4 2.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family RVT_3 PF13456.6 GBG72040.1 - 3.2e-26 91.6 0.0 4.7e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like zf-GRF PF06839.12 GBG72040.1 - 2.7e-13 49.7 6.4 6.5e-13 48.5 6.4 1.7 1 0 0 1 1 1 1 GRF zinc finger RNase_H PF00075.24 GBG72040.1 - 2.5e-05 24.5 0.0 6.4e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 RNase H LisH_2 PF16045.5 GBG72042.1 - 5.4e-10 38.1 0.2 8.1e-10 37.6 0.2 1.3 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 GBG72042.1 - 4.6e-09 36.4 0.0 8.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain DUF659 PF04937.15 GBG72043.1 - 5.7e-06 26.3 0.0 9.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) EF-hand_7 PF13499.6 GBG72044.1 - 3.2e-20 72.3 3.2 1.2e-08 35.2 3.7 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GBG72044.1 - 1.1e-18 65.5 7.6 0.00081 19.1 0.3 6.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 GBG72044.1 - 1.1e-18 65.3 4.6 2.6e-05 23.4 0.6 5.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 GBG72044.1 - 6.2e-10 38.8 4.9 0.046 13.6 0.5 5.6 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG72044.1 - 6.5e-10 38.1 5.9 0.0015 17.9 1.1 4.4 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 GBG72044.1 - 0.00011 22.5 3.6 0.91 9.9 1.1 4.1 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 GBG72044.1 - 0.00043 20.6 0.2 0.61 10.5 0.2 3.7 3 1 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 GBG72044.1 - 0.0011 18.8 2.5 3.2 7.7 0.1 4.0 4 0 0 4 4 4 1 EF hand LEM PF03020.15 GBG72044.1 - 0.013 15.1 0.0 0.077 12.6 0.0 2.4 3 0 0 3 3 3 0 LEM domain EF-hand_13 PF17958.1 GBG72044.1 - 0.018 14.9 0.1 21 5.0 0.1 4.0 3 1 0 3 3 3 0 EF-hand domain PAC3 PF10178.9 GBG72044.1 - 0.066 13.4 0.0 0.59 10.3 0.0 2.2 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 ProQ PF04352.13 GBG72044.1 - 0.096 12.6 0.1 12 5.8 0.0 2.7 2 0 0 2 2 2 0 ProQ/FINO family Claudin_2 PF13903.6 GBG72045.1 - 0.25 11.1 1.4 42 3.8 0.1 3.0 1 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Polyketide_cyc PF03364.20 GBG72046.1 - 1.3e-07 31.9 0.1 2e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GBG72046.1 - 2.9e-06 27.6 0.1 6.1e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SNF2_N PF00176.23 GBG72047.1 - 6e-59 199.5 0.0 6e-59 199.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG72047.1 - 4.5e-18 65.6 0.0 1.2e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 GBG72047.1 - 1.2e-16 60.4 30.3 1.3e-09 37.8 7.1 3.2 3 0 0 3 3 3 2 PHD-finger Chromo PF00385.24 GBG72047.1 - 2e-16 59.6 0.4 2.1e-09 37.1 0.0 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 GBG72047.1 - 8.3e-16 58.2 0.6 8.3e-16 58.2 0.6 4.2 4 0 0 4 4 4 1 PWWP domain HDA2-3 PF11496.8 GBG72047.1 - 3.7e-08 32.9 0.1 3.7e-08 32.9 0.1 2.5 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DUF1087 PF06465.13 GBG72047.1 - 1.6e-06 28.0 0.6 1.6e-06 28.0 0.6 3.8 4 0 0 4 4 4 1 Domain of Unknown Function (DUF1087) zf-HC5HC2H PF13771.6 GBG72047.1 - 0.12 12.7 13.9 0.35 11.2 0.7 3.1 3 0 0 3 3 3 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GBG72047.1 - 0.4 10.8 8.8 3.8 7.7 1.1 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain SNF2_N PF00176.23 GBG72048.1 - 6e-59 199.5 0.0 6e-59 199.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG72048.1 - 4.5e-18 65.6 0.0 1.2e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 GBG72048.1 - 1.2e-16 60.4 30.3 1.3e-09 37.8 7.1 3.2 3 0 0 3 3 3 2 PHD-finger Chromo PF00385.24 GBG72048.1 - 1.9e-16 59.7 0.4 2.1e-09 37.1 0.0 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 GBG72048.1 - 8.3e-16 58.2 0.6 8.3e-16 58.2 0.6 4.2 4 0 0 4 4 4 1 PWWP domain HDA2-3 PF11496.8 GBG72048.1 - 3.5e-08 33.0 0.1 3.5e-08 33.0 0.1 2.5 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DUF1087 PF06465.13 GBG72048.1 - 1.6e-06 28.0 0.6 1.6e-06 28.0 0.6 3.8 4 0 0 4 4 4 1 Domain of Unknown Function (DUF1087) zf-HC5HC2H PF13771.6 GBG72048.1 - 0.12 12.7 13.9 0.35 11.2 0.7 3.1 3 0 0 3 3 3 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GBG72048.1 - 0.4 10.9 8.8 3.8 7.7 1.1 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain Orai-1 PF07856.12 GBG72049.1 - 0.057 13.1 0.2 0.078 12.7 0.2 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity zf-CCHC PF00098.23 GBG72051.1 - 1e-06 28.5 1.1 2.1e-06 27.6 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG72051.1 - 0.0013 18.5 1.4 0.0025 17.6 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF2229 PF09989.9 GBG72051.1 - 0.15 11.7 0.5 0.23 11.1 0.5 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DEK_C PF08766.11 GBG72053.1 - 0.0017 18.3 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 DEK C terminal domain Ctr PF04145.15 GBG72054.1 - 2.6e-21 76.8 15.4 2.1e-19 70.6 15.4 2.0 1 1 0 1 1 1 1 Ctr copper transporter family Lyase_8 PF02278.18 GBG72054.1 - 0.32 10.4 2.2 0.68 9.4 2.2 1.4 1 1 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain DDE_Tnp_4 PF13359.6 GBG72056.1 - 4.1e-14 52.6 0.0 1.1e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72056.1 - 7.8e-07 28.9 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72056.1 - 0.0064 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain Antiterm PF03589.13 GBG72057.1 - 0.072 13.4 0.0 0.87 10.0 0.0 2.4 2 0 0 2 2 2 0 Antitermination protein DUF5320 PF17253.2 GBG72057.1 - 0.17 12.9 8.5 0.88 10.7 0.1 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5320) SIR4_SID PF16991.5 GBG72057.1 - 2.6 8.1 5.5 11 6.0 0.2 2.6 2 0 0 2 2 2 0 Sir4 SID domain DUF573 PF04504.14 GBG72057.1 - 5.4 7.7 12.4 9.5 7.0 0.3 3.5 3 1 0 3 3 3 0 Protein of unknown function, DUF573 Ctr PF04145.15 GBG72058.1 - 2e-17 64.2 0.9 2.4e-17 64.0 0.9 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DDE_Tnp_4 PF13359.6 GBG72059.1 - 3.2e-27 95.2 0.0 9.8e-27 93.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72059.1 - 5.9e-15 55.4 0.0 9.3e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72059.1 - 0.00071 19.3 0.6 0.013 15.1 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain Ctr PF04145.15 GBG72060.1 - 3.3e-09 37.5 0.6 3.3e-09 37.5 0.6 1.9 2 0 0 2 2 2 1 Ctr copper transporter family Myb_DNA-bind_4 PF13837.6 GBG72060.1 - 3.4e-08 33.8 3.5 8e-08 32.6 3.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG72060.1 - 0.00052 20.1 0.8 0.0014 18.7 0.8 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG72060.1 - 0.0039 17.4 0.7 0.0099 16.1 0.7 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG72060.1 - 0.028 14.5 1.1 0.053 13.6 1.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72060.1 - 0.05 13.9 0.8 0.11 12.8 0.8 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 GBG72061.1 - 2.2e-05 24.7 5.8 3.6e-05 24.0 3.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RecG_N PF17190.4 GBG72061.1 - 0.11 13.2 1.4 28 5.5 0.5 3.0 2 1 1 3 3 3 0 RecG N-terminal helical domain Nop14 PF04147.12 GBG72062.1 - 0.21 9.8 24.9 0.23 9.6 24.9 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG72062.1 - 1.9 7.9 25.9 2.2 7.6 25.9 1.1 1 0 0 1 1 1 0 SDA1 KAP PF05804.12 GBG72063.1 - 1.2e-182 608.8 9.6 1.5e-182 608.5 9.6 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) UCR_hinge PF02320.16 GBG72063.1 - 1.1e-17 64.0 5.4 2.5e-17 62.8 5.4 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF4632 PF15451.6 GBG72063.1 - 0.034 14.2 0.5 0.074 13.1 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) CX9C PF16860.5 GBG72063.1 - 0.18 11.8 5.3 2.7 8.1 5.3 2.4 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Arm PF00514.23 GBG72063.1 - 0.3 11.2 5.3 1.9 8.7 0.1 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat UCR_hinge PF02320.16 GBG72064.1 - 4.4e-21 74.8 3.8 4.9e-21 74.7 3.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CX9C PF16860.5 GBG72064.1 - 0.014 15.4 1.2 0.014 15.4 1.2 1.9 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, LELP1 PF15042.6 GBG72064.1 - 0.016 15.6 1.7 0.022 15.2 0.6 1.6 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 UPF0203 PF05254.12 GBG72064.1 - 1.3 9.3 6.8 1.3 9.3 2.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Nop14 PF04147.12 GBG72065.1 - 3.5 5.7 50.9 0.058 11.6 40.8 2.2 2 0 0 2 2 2 0 Nop14-like family Pkinase PF00069.25 GBG72066.1 - 0.00041 19.8 0.1 0.0082 15.5 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Retrotrans_gag PF03732.17 GBG72066.1 - 0.025 14.8 2.1 0.04 14.2 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein Nop14 PF04147.12 GBG72066.1 - 2.5 6.2 38.5 3.4 5.8 28.7 2.4 2 0 0 2 2 2 0 Nop14-like family Pkinase PF00069.25 GBG72067.1 - 0.021 14.2 0.2 0.4 10.0 0.1 2.4 2 0 0 2 2 2 0 Protein kinase domain Retrotrans_gag PF03732.17 GBG72067.1 - 0.024 14.9 2.1 0.039 14.2 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein Nop14 PF04147.12 GBG72067.1 - 2.4 6.3 38.5 3.3 5.8 28.7 2.4 2 0 0 2 2 2 0 Nop14-like family rve PF00665.26 GBG72069.1 - 6.2e-13 49.0 0.0 1.7e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG72069.1 - 4.5e-12 46.0 0.0 7.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG72069.1 - 2.6e-11 43.3 0.0 6.3e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG72070.1 - 6.5e-31 107.6 0.0 1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72070.1 - 4.4e-29 100.5 0.0 3.1e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72070.1 - 3.3e-27 94.8 0.0 7.1e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72070.1 - 5.9e-14 51.9 1.5 1.2e-13 51.0 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG72070.1 - 3.6e-12 46.0 0.0 7.7e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG72070.1 - 1.6e-07 31.5 0.0 5.4e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72070.1 - 0.0067 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG72071.1 - 1.1e-07 31.6 4.9 2.3e-07 30.6 4.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG72071.1 - 0.0047 16.7 2.3 0.011 15.6 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG72071.1 - 0.0096 15.6 2.5 0.0096 15.6 2.5 2.0 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger Prok-RING_1 PF14446.6 GBG72071.1 - 0.034 14.1 0.6 0.034 14.1 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RVT_1 PF00078.27 GBG72073.1 - 1.1e-15 57.8 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG72073.1 - 2.4e-05 24.2 2.8 4.9e-05 23.2 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle YL1 PF05764.13 GBG72073.1 - 0.0062 16.7 26.9 0.015 15.4 26.9 1.6 1 0 0 1 1 1 1 YL1 nuclear protein zf-CCHC_2 PF13696.6 GBG72073.1 - 0.045 13.6 2.1 0.09 12.6 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Lin-8 PF03353.15 GBG72073.1 - 0.076 12.6 12.5 0.12 11.9 12.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 GBG72073.1 - 0.94 8.8 32.5 1.8 7.9 32.5 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG72073.1 - 2.2 7.5 30.6 3.6 6.8 30.6 1.2 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG72073.1 - 6.6 5.4 16.0 11 4.7 16.0 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG72073.1 - 9.4 4.4 22.7 15 3.7 22.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Citrate_synt PF00285.21 GBG72074.1 - 8.5e-88 294.8 0.0 1.6e-51 175.5 0.0 2.1 2 0 0 2 2 2 2 Citrate synthase, C-terminal domain Peripla_BP_2 PF01497.18 GBG72075.1 - 6.4e-17 61.9 0.0 2.1e-15 56.9 0.0 2.6 3 0 0 3 3 3 1 Periplasmic binding protein Asn_synthase PF00733.21 GBG72075.1 - 5.5e-16 59.2 1.1 1.5e-11 44.6 0.2 3.0 3 0 0 3 3 3 2 Asparagine synthase Chromo PF00385.24 GBG72077.1 - 0.0016 18.3 0.1 0.0026 17.6 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG72078.1 - 6.9e-29 99.8 0.0 2e-28 98.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72078.1 - 5.7e-25 87.6 0.0 1.3e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72078.1 - 4.3e-15 55.8 0.0 6.4e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hid1 PF12722.7 GBG72078.1 - 7.4 4.6 12.9 14 3.7 12.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Guanylate_kin PF00625.21 GBG72079.1 - 4.1e-37 127.6 0.0 5.9e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 GBG72079.1 - 0.016 15.7 0.0 0.028 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GBG72079.1 - 0.036 14.0 0.2 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 GBG72079.1 - 0.07 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GBG72079.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Integrase_H2C2 PF17921.1 GBG72081.1 - 2.5e-13 49.9 0.3 9.6e-13 48.0 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG72081.1 - 5.6e-09 35.8 0.0 1.6e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG72081.1 - 6e-05 23.6 0.1 0.00016 22.3 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72081.1 - 0.0012 19.4 0.1 0.0035 17.9 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG72081.1 - 0.066 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase NPR3 PF03666.13 GBG72082.1 - 0.6 8.8 15.7 0.86 8.3 15.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GBG72082.1 - 3.3 6.4 13.1 4.4 6.0 13.1 1.2 1 0 0 1 1 1 0 Presenilin N6_N4_Mtase PF01555.18 GBG72083.1 - 3.6e-06 26.9 0.0 7.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 DNA methylase SURF2 PF05477.11 GBG72083.1 - 0.15 11.7 3.6 0.48 10.1 3.6 1.8 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2457 PF10446.9 GBG72083.1 - 0.16 11.1 10.2 0.31 10.1 10.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 GBG72083.1 - 0.49 8.5 14.9 0.44 8.7 13.3 1.6 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 GBG72083.1 - 1.7 8.0 20.1 0.072 12.5 14.0 1.7 2 0 0 2 2 2 0 SDA1 PPP4R2 PF09184.11 GBG72084.1 - 0.21 11.2 10.8 0.35 10.4 10.8 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GBG72084.1 - 0.39 8.9 20.1 0.69 8.1 20.1 1.3 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG72084.1 - 1 7.4 19.9 1.4 6.9 19.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GBG72084.1 - 1 8.6 15.3 2.1 7.6 15.3 1.5 1 0 0 1 1 1 0 NOA36 protein E2F_TDP PF02319.20 GBG72085.1 - 1.3e-13 50.8 0.0 3.4e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Nitr_red_alph_N PF14710.6 GBG72086.1 - 0.087 13.3 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 Respiratory nitrate reductase alpha N-terminal rve PF00665.26 GBG72087.1 - 1.1e-13 51.4 0.0 3.4e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG72087.1 - 1.6e-11 44.0 0.0 3.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG72087.1 - 1.6e-07 31.3 1.9 4.2e-07 30.0 0.1 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG72087.1 - 0.024 14.8 0.1 0.067 13.4 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger MDM1 PF15501.6 GBG72089.1 - 0.0036 16.5 19.5 0.0057 15.9 19.5 1.2 1 0 0 1 1 1 1 Nuclear protein MDM1 DUF3161 PF11362.8 GBG72089.1 - 0.037 14.0 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Presenilin PF01080.17 GBG72089.1 - 0.11 11.2 12.3 0.17 10.6 12.3 1.2 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 GBG72089.1 - 0.15 11.0 7.1 0.17 10.9 7.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GAGA_bind PF06217.12 GBG72089.1 - 0.15 12.3 12.0 0.2 11.9 12.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family NPR3 PF03666.13 GBG72089.1 - 2.3 6.9 15.2 3.7 6.2 15.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 GBG72089.1 - 3 5.8 8.2 3.5 5.6 8.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2967 PF11179.8 GBG72089.1 - 4.4 5.3 11.2 5.4 5.0 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) FYDLN_acid PF09538.10 GBG72089.1 - 6.4 7.5 18.4 0.093 13.4 7.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) V_ATPase_I PF01496.19 GBG72089.1 - 6.7 4.5 12.5 11 3.7 12.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RVT_1 PF00078.27 GBG72090.1 - 8.1e-11 41.9 0.1 1.6e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG72090.1 - 1.5e-05 24.8 3.2 3.8e-05 23.6 3.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG72090.1 - 0.016 15.8 0.0 0.043 14.5 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG72090.1 - 0.032 14.8 0.1 0.074 13.6 0.1 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG72090.1 - 0.035 13.9 4.1 0.074 12.9 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle MyTH4 PF00784.17 GBG72091.1 - 7.7e-26 90.7 0.0 2.1e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain MyTH4 PF00784.17 GBG72092.1 - 7.7e-26 90.7 0.0 2.1e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain GTP_EFTU PF00009.27 GBG72093.1 - 3.6e-42 144.1 1.0 4.4e-41 140.6 1.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GBG72093.1 - 3.5e-21 75.6 0.0 7.4e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 GBG72093.1 - 8.2e-05 22.7 0.0 0.0029 17.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GBG72093.1 - 0.072 13.0 2.8 0.45 10.5 2.6 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 MFS_1 PF07690.16 GBG72094.1 - 7.7e-30 104.0 33.8 2e-29 102.7 30.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.27 GBG72094.1 - 9.9e-26 90.6 0.1 1.6e-25 90.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OATP PF03137.20 GBG72094.1 - 7.1e-20 70.8 16.1 4.2e-17 61.7 8.6 5.0 2 2 2 4 4 3 2 Organic Anion Transporter Polypeptide (OATP) family RT_RNaseH_2 PF17919.1 GBG72094.1 - 2e-19 69.4 0.0 5.6e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72094.1 - 2.8e-08 34.0 0.0 6.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MFS_4 PF06779.14 GBG72094.1 - 0.00073 18.9 1.9 0.00073 18.9 1.9 2.1 2 0 0 2 2 1 1 Uncharacterised MFS-type transporter YbfB gag-asp_proteas PF13975.6 GBG72094.1 - 0.012 16.1 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG72094.1 - 0.023 14.9 0.1 0.059 13.6 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_3 PF13917.6 GBG72094.1 - 0.027 14.4 0.5 0.055 13.4 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Apt1 PF10351.9 GBG72094.1 - 0.037 12.9 10.8 0.073 11.9 10.8 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-CCHC PF00098.23 GBG72094.1 - 2.9 8.1 4.9 7 6.9 4.9 1.7 1 0 0 1 1 1 0 Zinc knuckle SRP-alpha_N PF04086.13 GBG72094.1 - 9.4 6.1 45.6 0.082 12.8 2.7 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Cwf_Cwc_15 PF04889.12 GBG72096.1 - 0.084 12.6 8.2 0.11 12.2 8.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG72096.1 - 0.12 10.6 6.7 0.11 10.8 6.7 1.0 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 GBG72096.1 - 0.25 11.0 2.8 0.087 12.5 0.5 1.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Pes-10 PF07149.11 GBG72096.1 - 1.4 7.9 5.8 1.6 7.7 5.8 1.0 1 0 0 1 1 1 0 Pes-10 PGA2 PF07543.12 GBG72096.1 - 1.9 8.5 7.9 2.9 7.9 7.9 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Nop14 PF04147.12 GBG72096.1 - 4 5.5 13.1 4.9 5.2 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family Sel1 PF08238.12 GBG72098.1 - 0.00023 21.7 0.2 0.00023 21.7 0.2 4.6 5 0 0 5 5 5 2 Sel1 repeat IHABP4_N PF16174.5 GBG72099.1 - 0.64 10.6 7.7 1.5 9.4 7.7 1.6 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF659 PF04937.15 GBG72100.1 - 8.7e-14 51.6 0.0 1.4e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-primase PF09329.11 GBG72101.1 - 0.047 13.5 0.4 0.074 12.9 0.4 1.3 1 0 0 1 1 1 0 Primase zinc finger HATPase_c PF02518.26 GBG72103.1 - 5.1e-16 59.2 0.4 8.3e-14 52.0 0.2 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GBG72103.1 - 0.034 14.3 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 Response regulator receiver domain RT_RNaseH_2 PF17919.1 GBG72105.1 - 4.5e-32 110.1 0.0 9.1e-32 109.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72105.1 - 6.8e-28 97.0 0.1 1.5e-27 95.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72105.1 - 1.2e-19 70.2 0.1 2.8e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG72105.1 - 2.5e-18 66.4 0.0 5e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG72105.1 - 4e-09 36.7 0.0 1.5e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72105.1 - 0.00019 21.6 0.0 0.00077 19.6 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG72106.1 - 6.8e-25 87.0 0.0 1.5e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72106.1 - 1.2e-23 83.4 0.1 3e-23 82.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72106.1 - 1.9e-15 56.7 3.3 1.9e-14 53.5 0.6 3.2 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG72106.1 - 2.2e-06 27.8 0.0 7.2e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG72106.1 - 0.00031 20.6 0.0 0.00085 19.2 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG72106.1 - 0.024 14.8 0.4 0.069 13.4 0.4 1.9 1 0 0 1 1 1 0 H2C2 zinc finger NST1 PF13945.6 GBG72107.1 - 3.5 7.7 11.6 5.5 7.1 11.6 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator HATPase_c PF02518.26 GBG72110.1 - 5.1e-21 75.3 0.5 2.8e-18 66.4 0.4 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GBG72110.1 - 3.3e-06 27.0 0.1 8.5e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 GBG72110.1 - 0.0029 18.2 0.0 0.59 10.8 0.0 2.7 2 0 0 2 2 2 1 GAF domain GntR PF00392.21 GBG72110.1 - 0.077 12.7 0.1 0.24 11.1 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family PTPRCAP PF15713.5 GBG72111.1 - 0.079 13.2 0.2 0.12 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Ribosomal_L24e PF01246.20 GBG72112.1 - 3.2e-33 113.8 4.6 3.2e-33 113.8 4.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 GBG72112.1 - 0.11 12.5 3.5 0.24 11.4 3.1 1.8 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RT_RNaseH_2 PF17919.1 GBG72113.1 - 9.4e-30 102.6 0.0 1.4e-25 89.3 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72113.1 - 2.7e-22 79.1 0.0 7.3e-22 77.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72113.1 - 1.5e-13 50.8 0.7 1.4e-10 41.1 0.0 3.2 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72114.1 - 8.8e-28 96.2 3.3 3.3e-19 68.7 0.6 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG72114.1 - 3e-22 78.9 0.0 6.2e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72114.1 - 1.3e-21 76.5 0.0 2.4e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72114.1 - 1.6e-09 37.6 0.0 2.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG72114.1 - 8.4e-09 35.5 1.0 0.0029 17.8 0.1 2.7 2 0 0 2 2 2 2 H2C2 zinc finger rve PF00665.26 GBG72114.1 - 3.4e-06 27.2 0.0 0.041 14.1 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain Asp_protease_2 PF13650.6 GBG72114.1 - 0.0011 19.5 0.1 0.0039 17.8 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG72114.1 - 0.027 14.3 0.1 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG72114.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Metallophos PF00149.28 GBG72115.1 - 1.8e-20 74.3 0.0 2.8e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pilin_N PF07790.11 GBG72115.1 - 0.089 13.7 0.6 0.16 12.9 0.6 1.4 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Cyclin_N PF00134.23 GBG72116.1 - 1.5e-46 157.3 1.5 2.8e-46 156.4 1.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GBG72116.1 - 2e-35 121.4 0.1 4.6e-35 120.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Retrotrans_gag PF03732.17 GBG72117.1 - 0.0065 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotrans_gag PF03732.17 GBG72119.1 - 0.001 19.3 0.0 0.0046 17.2 0.0 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein Dimer_Tnp_hAT PF05699.14 GBG72120.1 - 0.0081 15.9 0.4 0.015 15.1 0.4 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DOMON PF03351.17 GBG72121.1 - 2.1e-06 28.0 0.0 5.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 GBG72121.1 - 0.00036 20.3 5.2 0.001 18.8 5.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 GBG72121.1 - 0.0006 19.9 13.5 0.0006 19.9 13.5 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 GBG72122.1 - 1.3e-05 25.4 0.0 3.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 GBG72122.1 - 0.0056 16.8 8.0 0.01 16.0 8.0 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 GBG72122.1 - 0.16 11.8 7.4 0.072 12.9 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) CRS1_YhbY PF01985.21 GBG72124.1 - 6.9e-17 61.4 0.3 1.3e-16 60.5 0.3 1.5 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain Sigma70_ner PF04546.13 GBG72125.1 - 4 7.3 39.9 0.61 9.9 10.1 2.1 1 1 1 2 2 2 0 Sigma-70, non-essential region Membralin PF09746.9 GBG72125.1 - 5.9 5.8 10.4 6.3 5.7 10.4 1.2 1 0 0 1 1 1 0 Tumour-associated protein RT_RNaseH PF17917.1 GBG72127.1 - 8.2e-25 87.1 0.2 2.4e-24 85.6 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72127.1 - 3.4e-16 59.1 0.0 1.8e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_lysozyme PF00959.19 GBG72127.1 - 0.072 13.5 0.2 1 9.8 0.0 3.0 3 0 0 3 3 3 0 Phage lysozyme ADP_ribosyl_GH PF03747.14 GBG72127.1 - 0.12 12.1 0.0 0.12 12.1 0.0 2.8 2 1 1 3 3 3 0 ADP-ribosylglycohydrolase DUF4360 PF14273.6 GBG72128.1 - 1.1e-18 67.8 1.5 1.3e-18 67.5 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RVT_1 PF00078.27 GBG72129.1 - 8.7e-27 94.1 0.1 1.4e-26 93.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72129.1 - 3.9e-15 55.7 0.0 9e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72129.1 - 9.5e-08 32.3 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72129.1 - 4.2e-06 26.9 0.0 1.3e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger AdoHcyase PF05221.17 GBG72130.1 - 1.3e-136 454.6 0.0 1.5e-136 454.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GBG72130.1 - 4.3e-73 244.7 1.6 7.5e-73 243.9 1.6 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GBG72130.1 - 6.9e-05 22.3 0.4 0.00013 21.4 0.4 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GBG72130.1 - 0.00065 19.3 0.9 0.0012 18.4 0.9 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 GBG72130.1 - 0.0014 18.7 0.5 0.0037 17.3 0.5 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 GBG72130.1 - 0.0027 18.1 0.3 0.0073 16.7 0.3 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 GBG72130.1 - 0.045 14.0 0.1 0.12 12.7 0.1 1.8 1 1 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 GBG72130.1 - 0.079 13.6 0.6 0.24 12.0 0.6 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent S4 PF01479.25 GBG72131.1 - 2.3e-13 49.6 0.8 5.4e-13 48.4 0.8 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 GBG72131.1 - 3.5e-07 31.0 2.7 1.3e-06 29.2 2.4 2.2 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Nucleotid_trans PF03407.16 GBG72132.1 - 5.7e-28 98.3 0.0 9.6e-27 94.3 0.0 2.4 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase RNA_pol_Rpc4 PF05132.14 GBG72132.1 - 0.0031 17.9 0.1 2.7 8.4 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase III RPC4 MPM1 PF17234.2 GBG72132.1 - 0.023 15.0 0.4 0.023 15.0 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 U1snRNP70_N PF12220.8 GBG72132.1 - 2.2 9.0 6.5 5 7.8 6.5 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Secretin_N_2 PF07655.13 GBG72132.1 - 4.5 7.9 10.9 15 6.2 10.9 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain RPA43_OB PF17875.1 GBG72132.1 - 6 7.5 7.6 91 3.7 4.9 2.6 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF2781 PF10914.8 GBG72133.1 - 0.082 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF2921 PF11145.8 GBG72134.1 - 1.6e-21 76.0 1.7 1.6e-09 36.2 3.4 3.4 2 2 0 2 2 2 2 Protein of unknown function (DUF2921) DUF1031 PF06275.11 GBG72134.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) DUF4131 PF13567.6 GBG72134.1 - 5.6 6.6 10.2 0.15 11.7 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4360 PF14273.6 GBG72135.1 - 1.1e-34 119.8 0.0 1.3e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF2866 PF11065.8 GBG72135.1 - 0.037 14.0 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) APG6_N PF17675.1 GBG72136.1 - 0.18 12.3 7.8 1.9 9.0 3.7 3.2 2 1 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 GBG72136.1 - 0.31 10.8 0.2 0.31 10.8 0.2 4.0 3 1 2 5 5 5 0 Septum formation initiator TolA_bind_tri PF16331.5 GBG72136.1 - 0.33 11.1 10.2 0.16 12.0 0.9 3.7 2 1 2 4 4 4 0 TolA binding protein trimerisation Fez1 PF06818.15 GBG72136.1 - 0.36 11.3 12.9 1.7 9.0 6.2 2.2 2 0 0 2 2 2 0 Fez1 Myb_DNA-bind_4 PF13837.6 GBG72137.1 - 7.4e-07 29.5 3.2 1.7e-05 25.1 0.9 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG72138.1 - 1.2e-26 93.2 0.0 6.2e-26 91.0 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72138.1 - 6.6e-16 58.5 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72138.1 - 1.9e-08 34.2 0.2 9.9e-05 22.1 0.0 3.2 2 1 0 2 2 2 2 Transposase DDE domain DUF4360 PF14273.6 GBG72139.1 - 1.7e-33 115.9 0.0 2.4e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pep_deformylase PF01327.21 GBG72140.1 - 5.8e-48 162.5 0.0 9e-48 161.9 0.0 1.3 1 0 0 1 1 1 1 Polypeptide deformylase DUF4187 PF13821.6 GBG72140.1 - 0.0053 16.5 0.4 0.012 15.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) SLC12 PF03522.15 GBG72141.1 - 0.13 11.2 1.6 0.17 10.9 1.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 GBG72141.1 - 6.5 5.5 5.7 9.2 5.0 5.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 GBG72141.1 - 8.3 5.1 11.3 12 4.6 11.3 1.2 1 0 0 1 1 1 0 Presenilin DUF4360 PF14273.6 GBG72143.1 - 2.2e-34 118.9 0.0 2.6e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RVT_1 PF00078.27 GBG72144.1 - 9.3e-29 100.5 0.1 1.6e-28 99.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72144.1 - 1.8e-09 37.5 0.0 5.8e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG72144.1 - 0.031 14.1 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG72145.1 - 3.5e-33 115.0 0.0 6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72145.1 - 6.1e-30 103.2 0.0 5.9e-29 100.1 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72145.1 - 2.3e-29 101.8 0.1 6.2e-29 100.4 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG72145.1 - 0.00035 20.4 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72145.1 - 0.0011 19.5 0.0 0.0025 18.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72145.1 - 0.0051 17.3 0.0 0.017 15.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG72145.1 - 0.045 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG72145.1 - 0.13 12.1 0.0 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease FlaC_arch PF05377.11 GBG72147.1 - 0.0005 20.4 2.8 0.00091 19.6 0.6 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) 4HB_MCP_1 PF12729.7 GBG72147.1 - 0.0021 17.6 4.5 0.0048 16.5 0.4 2.5 2 1 0 2 2 2 1 Four helix bundle sensory module for signal transduction VHL_C PF17211.3 GBG72147.1 - 0.045 13.8 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 VHL box domain GrpE PF01025.19 GBG72147.1 - 0.057 13.1 12.4 1.2 8.7 4.2 3.0 3 0 0 3 3 3 0 GrpE PEP-utilisers_N PF05524.13 GBG72147.1 - 0.062 13.5 5.1 3.5 7.8 0.1 2.9 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal OmpH PF03938.14 GBG72147.1 - 0.083 13.2 14.7 1.2 9.4 4.7 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF87 PF01935.17 GBG72147.1 - 0.46 10.5 3.1 5.2 7.1 1.6 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain XhlA PF10779.9 GBG72147.1 - 0.47 10.7 7.9 2.7 8.2 0.1 2.9 2 0 0 2 2 2 0 Haemolysin XhlA LMBR1 PF04791.16 GBG72147.1 - 0.66 8.8 1.3 0.87 8.4 1.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Syntaxin_2 PF14523.6 GBG72147.1 - 0.75 10.2 8.0 4.6 7.7 0.5 3.4 3 1 0 3 3 3 0 Syntaxin-like protein Syntaxin-6_N PF09177.11 GBG72147.1 - 1.2 9.7 7.2 0.22 12.1 0.5 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal ZapB PF06005.12 GBG72147.1 - 3.2 8.3 19.6 2.1 8.9 5.5 3.3 3 1 0 3 3 3 0 Cell division protein ZapB V_ATPase_I PF01496.19 GBG72147.1 - 3.6 5.4 7.8 15 3.3 7.8 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 GBG72147.1 - 3.9 7.5 11.8 0.53 10.4 7.6 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 GBG72147.1 - 4.9 7.8 11.8 3.3 8.4 0.2 3.1 3 0 0 3 3 3 0 Initiation control protein YabA DUF3450 PF11932.8 GBG72147.1 - 6.8 5.9 8.8 0.57 9.4 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) FapA PF03961.13 GBG72147.1 - 6.9 5.1 9.7 0.17 10.5 1.1 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4360 PF14273.6 GBG72148.1 - 1e-26 93.9 1.4 1.2e-26 93.7 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) gag-asp_proteas PF13975.6 GBG72149.1 - 2e-08 34.7 0.0 5.9e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72149.1 - 6.2e-05 23.6 0.0 0.00015 22.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG72149.1 - 0.00079 19.2 0.6 0.0015 18.3 0.6 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG72149.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG72149.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain Lamprin PF06403.11 GBG72149.1 - 0.21 11.5 7.1 0.48 10.4 7.1 1.5 1 0 0 1 1 1 0 Lamprin Myb_DNA-bind_4 PF13837.6 GBG72150.1 - 6.7e-11 42.4 1.0 1.9e-10 40.9 0.2 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72150.1 - 0.021 15.1 0.2 0.047 14.0 0.2 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG72151.1 - 3.3e-32 111.4 0.0 4.8e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72151.1 - 1.8e-10 40.7 0.0 2.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein S100PBPR PF15427.6 GBG72151.1 - 0.44 9.7 5.5 0.66 9.2 5.5 1.2 1 0 0 1 1 1 0 S100P-binding protein RVT_1 PF00078.27 GBG72152.1 - 3.3e-26 92.2 0.2 1.4e-25 90.1 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72152.1 - 1.8e-23 82.4 0.0 5.6e-23 80.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72152.1 - 7.4e-23 80.8 0.0 2.3e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72152.1 - 2.3e-17 62.9 0.0 5.2e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG72152.1 - 6.6e-07 29.2 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG72152.1 - 4.6e-06 26.8 0.0 1.9e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG72152.1 - 3.2e-05 24.5 0.0 7.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72152.1 - 3.9e-05 24.1 0.0 9.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG72152.1 - 0.0035 17.6 0.1 0.019 15.3 0.1 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein SlyX PF04102.12 GBG72152.1 - 0.016 15.9 0.2 0.016 15.9 0.2 3.6 4 0 0 4 4 2 0 SlyX CEP1-DNA_bind PF09287.10 GBG72152.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 CEP-1, DNA binding Tudor-knot PF11717.8 GBG72152.1 - 0.085 12.8 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain TolA_bind_tri PF16331.5 GBG72152.1 - 1.2 9.3 6.4 2.5 8.3 5.3 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation RT_RNaseH_2 PF17919.1 GBG72153.1 - 1e-33 115.3 0.0 3.1e-33 113.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72153.1 - 6.2e-30 103.6 0.1 1.4e-29 102.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72153.1 - 1.3e-26 93.5 0.1 2.1e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG72153.1 - 0.00025 21.5 0.0 0.00078 20.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG72153.1 - 0.0046 16.7 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.6 GBG72153.1 - 0.012 15.6 1.8 0.029 14.3 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 GBG72153.1 - 0.02 15.5 0.0 0.064 13.9 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease NAAA-beta PF15508.6 GBG72153.1 - 0.11 12.8 0.1 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Apc13p PF05839.11 GBG72153.1 - 0.13 12.5 0.2 0.58 10.4 0.2 2.1 1 0 0 1 1 1 0 Apc13p protein YTH PF04146.15 GBG72155.1 - 2.9e-39 134.7 0.0 2.9e-39 134.7 0.0 3.0 3 1 0 3 3 3 1 YT521-B-like domain CD99L2 PF12301.8 GBG72155.1 - 0.12 12.7 6.1 0.35 11.1 6.1 1.7 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF2052 PF09747.9 GBG72155.1 - 2.5 8.2 22.5 0.045 13.9 1.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SUIM_assoc PF16619.5 GBG72155.1 - 3.1 7.9 20.0 4 7.6 5.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DDE_Tnp_4 PF13359.6 GBG72157.1 - 4e-15 55.8 0.0 3.6e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72157.1 - 1.3e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72157.1 - 0.19 11.3 0.2 1.6 8.4 0.0 2.3 3 0 0 3 3 3 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG72158.1 - 5.7e-10 39.4 0.7 1.4e-09 38.2 0.7 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG72158.1 - 0.00022 21.2 2.0 0.00048 20.2 2.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Rit1_C PF17184.4 GBG72158.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Rit1 N-terminal domain Mlo PF03094.15 GBG72159.1 - 1.2e-57 195.4 2.3 2.2e-29 102.2 0.1 2.3 3 0 0 3 3 3 2 Mlo family CDC45 PF02724.14 GBG72159.1 - 2.9 6.1 12.6 4.5 5.4 12.6 1.3 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 GBG72159.1 - 6 5.8 7.6 9.7 5.2 7.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 GBG72160.1 - 0.34 9.6 8.4 0.48 9.1 8.4 1.1 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.13 GBG72160.1 - 2.7 6.5 9.5 3.5 6.1 9.5 1.1 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 GBG72160.1 - 8 5.4 11.0 12 4.8 11.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Retrotrans_gag PF03732.17 GBG72161.1 - 0.0008 19.6 6.4 0.014 15.6 0.3 3.8 3 1 1 4 4 4 2 Retrotransposon gag protein Use1 PF09753.9 GBG72161.1 - 0.36 10.5 6.9 0.22 11.2 4.0 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF3006 PF11213.8 GBG72161.1 - 2.6 8.4 6.5 2.1 8.6 4.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) Trypsin PF00089.26 GBG72162.1 - 5.6e-39 134.2 0.0 6.1e-38 130.8 0.0 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GBG72162.1 - 5.6e-05 24.1 0.0 0.00024 22.0 0.0 2.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain RVP_2 PF08284.11 GBG72163.1 - 2.6e-09 37.0 0.0 6.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72163.1 - 9.7e-09 35.8 0.0 3.4e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72163.1 - 6.3e-08 33.1 0.0 2.3e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG72163.1 - 0.0029 17.4 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG72163.1 - 0.062 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Matrilin_ccoil PF10393.9 GBG72163.1 - 0.11 12.4 0.5 0.29 11.0 0.5 1.8 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DASH_Spc34 PF08657.10 GBG72163.1 - 0.24 11.1 6.9 0.78 9.5 6.2 2.0 2 1 0 2 2 2 0 DASH complex subunit Spc34 Transposase_24 PF03004.14 GBG72163.1 - 3.6 7.7 7.4 2.6 8.1 2.8 2.4 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF16 PF01519.16 GBG72163.1 - 5 7.7 5.9 1.5 9.3 2.4 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 SR-25 PF10500.9 GBG72165.1 - 0.0034 17.0 11.7 0.0034 17.0 11.7 2.3 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF3899 PF13038.6 GBG72165.1 - 1.4 9.5 7.1 9.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF4604 PF15377.6 GBG72165.1 - 4.3 7.7 17.3 6.1 7.2 17.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) BCIP PF13862.6 GBG72165.1 - 9.3 6.0 8.5 14 5.3 8.5 1.2 1 0 0 1 1 1 0 p21-C-terminal region-binding protein AP3D1 PF06375.11 GBG72165.1 - 9.4 6.5 21.2 1.6 8.9 17.0 1.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 RVT_1 PF00078.27 GBG72166.1 - 1.6e-09 37.6 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1681 PF07933.14 GBG72170.1 - 5.5e-52 175.4 0.0 7.4e-52 175.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) RTC PF01137.21 GBG72172.1 - 2.5e-53 180.6 0.1 2.9e-53 180.4 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 GBG72172.1 - 1.4e-39 134.8 0.1 3e-39 133.7 0.1 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain TPT PF03151.16 GBG72173.1 - 5.1e-110 367.4 23.2 6.5e-110 367.0 23.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG72173.1 - 8.9e-13 48.6 29.2 8.7e-09 35.7 11.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GBG72173.1 - 4.7e-06 26.0 16.0 6.7e-06 25.5 16.0 1.2 1 0 0 1 1 1 1 UAA transporter family K_channel_TID PF07941.11 GBG72173.1 - 0.14 12.6 7.0 0.36 11.3 7.0 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF1003 PF06210.11 GBG72173.1 - 3.7 7.7 4.4 2.1 8.5 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Sdh_cyt PF01127.22 GBG72173.1 - 8.4 6.5 12.6 0.19 11.8 2.8 2.5 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Mlh1_C PF16413.5 GBG72174.1 - 7.1e-84 281.4 0.0 1.8e-83 280.0 0.0 1.7 1 1 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 GBG72174.1 - 2.2e-32 111.2 0.0 4.4e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 GBG72174.1 - 0.0052 16.6 0.1 3.3 7.5 0.0 2.5 2 0 0 2 2 2 2 MutL C terminal dimerisation domain AAA_13 PF13166.6 GBG72174.1 - 0.09 11.4 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain MCM2_N PF12619.8 GBG72174.1 - 1.3 9.3 6.5 5.5 7.3 4.0 2.5 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 Macoilin PF09726.9 GBG72175.1 - 3.6 6.0 7.2 4.2 5.8 7.2 1.1 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 GBG72175.1 - 7.7 4.7 13.4 11 4.3 13.4 1.2 1 0 0 1 1 1 0 Menin FKBP_C PF00254.28 GBG72178.1 - 7.5e-26 90.3 0.0 1.3e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CsgG PF03783.14 GBG72178.1 - 0.013 14.8 1.9 0.019 14.2 1.9 1.2 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG ATP-synt_E PF05680.12 GBG72178.1 - 3.5 8.0 8.2 5.7 7.3 8.2 1.2 1 0 0 1 1 1 0 ATP synthase E chain DUF3504 PF12012.8 GBG72179.1 - 5.1e-08 33.0 1.1 7.8e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) Herpes_UL6 PF01763.16 GBG72179.1 - 0.047 12.2 2.8 0.03 12.9 1.4 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like Tet_JBP PF12851.7 GBG72179.1 - 0.082 12.2 0.9 0.13 11.6 0.9 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Dimer_Tnp_hAT PF05699.14 GBG72181.1 - 1.6e-06 27.8 0.6 2.6e-06 27.1 0.6 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RNA_pol_3_Rpc31 PF11705.8 GBG72181.1 - 0.012 15.9 9.9 0.018 15.3 9.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Paf1 PF03985.13 GBG72181.1 - 0.033 13.2 7.2 0.043 12.8 7.2 1.2 1 0 0 1 1 1 0 Paf1 PPP4R2 PF09184.11 GBG72181.1 - 0.49 9.9 10.1 0.64 9.6 10.1 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 GBG72181.1 - 0.7 9.3 13.8 0.99 8.8 13.8 1.2 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 GBG72181.1 - 3.3 7.5 7.2 5.5 6.7 7.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 GBG72181.1 - 3.8 6.7 14.6 5.5 6.2 14.6 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GBG72181.1 - 4.5 5.3 14.1 6 4.9 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 GBG72181.1 - 7.8 6.2 9.9 14 5.4 9.9 1.3 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 GBG72181.1 - 8.3 4.4 18.0 12 3.9 18.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF659 PF04937.15 GBG72182.1 - 1.7e-06 28.0 0.1 5.9e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) SDA1 PF05285.12 GBG72183.1 - 0.087 12.2 40.9 0.11 11.9 40.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG72183.1 - 0.62 8.2 41.7 0.9 7.7 41.7 1.4 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG72183.1 - 0.72 9.1 35.6 0.86 8.9 35.6 1.3 1 0 0 1 1 1 0 BUD22 CCSAP PF15748.5 GBG72183.1 - 0.74 9.9 10.0 0.97 9.5 10.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF1681 PF07933.14 GBG72185.1 - 6.6e-52 175.2 0.0 9.5e-52 174.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF3082 PF11282.8 GBG72187.1 - 9.9e-07 28.9 2.9 2.6e-06 27.6 2.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) COPI_C PF06957.11 GBG72188.1 - 0.00022 20.1 0.2 0.0027 16.5 0.1 2.3 2 0 0 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 GBG72188.1 - 0.0041 16.2 0.0 0.061 12.4 0.0 2.7 4 0 0 4 4 4 1 Coatomer WD associated region Fis1_TPR_C PF14853.6 GBG72188.1 - 0.0065 16.5 0.0 0.044 13.9 0.0 2.2 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 GBG72188.1 - 0.021 14.9 1.4 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG72188.1 - 0.074 13.6 0.0 1.5 9.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PSII_BNR PF14870.6 GBG72189.1 - 9.8e-123 409.2 1.6 1.2e-122 409.0 1.6 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 GBG72189.1 - 7.7e-09 34.9 0.0 0.0046 15.8 0.0 3.1 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 GBG72189.1 - 8.3e-08 31.1 9.4 0.43 10.8 0.1 5.7 4 0 0 4 4 4 4 BNR/Asp-box repeat DUF4185 PF13810.6 GBG72189.1 - 0.0081 15.4 0.1 0.093 11.9 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4185) TPT PF03151.16 GBG72191.1 - 6.6e-112 373.6 26.2 7.7e-112 373.4 26.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG72191.1 - 3.7e-13 49.8 35.9 7.8e-10 39.1 15.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GBG72191.1 - 1.5e-05 24.3 17.8 3.1e-05 23.3 17.8 1.6 1 1 0 1 1 1 1 UAA transporter family Bac_RepA_C PF18008.1 GBG72192.1 - 0.16 12.4 1.8 0.59 10.5 0.0 2.2 2 1 0 2 2 2 0 Replication initiator protein A C-terminal domain DUF1043 PF06295.12 GBG72192.1 - 0.32 11.0 9.5 0.027 14.5 4.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) DUF4407 PF14362.6 GBG72192.1 - 0.74 9.1 3.1 1 8.7 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 GBG72192.1 - 1.6 7.8 8.1 2.5 7.1 8.1 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 GBG72192.1 - 2.2 8.6 8.8 0.4 11.0 3.3 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) LMBR1 PF04791.16 GBG72192.1 - 4.6 6.0 4.6 5.9 5.7 4.6 1.2 1 1 0 1 1 1 0 LMBR1-like membrane protein GrpE PF01025.19 GBG72192.1 - 4.7 6.8 15.3 0.85 9.3 8.7 2.2 2 1 0 2 2 2 0 GrpE DUF4680 PF15730.5 GBG72192.1 - 6.9 7.0 10.9 0.61 10.4 1.6 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4680) DHR10 PF18595.1 GBG72194.1 - 6.4 6.9 6.9 0.16 12.0 0.7 1.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain WD40 PF00400.32 GBG72195.1 - 2e-10 41.0 15.3 0.011 16.5 0.3 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG72195.1 - 1.5e-05 25.2 0.0 1.6 9.0 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain UTP15_C PF09384.10 GBG72195.1 - 0.0004 20.1 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal Nup160 PF11715.8 GBG72195.1 - 0.01 14.6 0.1 0.064 11.9 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40 PF00400.32 GBG72196.1 - 2e-10 41.1 15.3 0.011 16.5 0.3 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG72196.1 - 1.4e-05 25.2 0.0 1.6 9.1 0.0 4.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UTP15_C PF09384.10 GBG72196.1 - 0.00034 20.3 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal Nup160 PF11715.8 GBG72196.1 - 0.01 14.6 0.1 0.064 11.9 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Bac_rhamnosid_N PF08531.10 GBG72196.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain RT_RNaseH PF17917.1 GBG72198.1 - 4.3e-19 68.7 0.0 6.5e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72198.1 - 3.7e-09 36.5 0.0 6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PTPRCAP PF15713.5 GBG72198.1 - 0.028 14.7 6.4 0.056 13.7 6.4 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GBG72198.1 - 0.11 10.7 6.6 0.12 10.5 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG72198.1 - 0.38 10.1 6.9 0.48 9.8 6.9 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG72198.1 - 0.94 7.7 5.9 1.1 7.4 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG72198.1 - 4.9 6.4 13.1 6.9 5.9 13.1 1.3 1 0 0 1 1 1 0 BUD22 DDE_Tnp_4 PF13359.6 GBG72202.1 - 3.7e-23 82.0 0.0 6.6e-23 81.1 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72202.1 - 3.1e-11 43.3 0.0 5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein UcrQ PF02939.16 GBG72202.1 - 0.12 12.3 0.2 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 UcrQ family FAP PF07174.11 GBG72203.1 - 4.6 6.6 33.1 7 6.0 33.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4407 PF14362.6 GBG72204.1 - 5 6.4 16.5 13 5.0 16.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4990 PF16380.5 GBG72205.1 - 0.0099 16.0 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UvsW PF11637.8 GBG72205.1 - 0.18 11.9 0.3 7.3 6.8 0.0 2.2 2 0 0 2 2 2 0 ATP-dependant DNA helicase UvsW RVT_1 PF00078.27 GBG72207.1 - 2.3e-29 102.5 0.1 3.4e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72207.1 - 4.7e-16 58.7 0.0 9.5e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72207.1 - 9.3e-15 54.5 1.2 2.1e-07 31.0 0.0 3.1 3 0 0 3 3 3 2 Integrase zinc binding domain rve PF00665.26 GBG72207.1 - 5.6e-13 49.1 0.2 3.1e-12 46.7 0.0 2.3 2 1 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG72207.1 - 0.00025 21.2 0.4 0.46 10.8 0.1 2.7 1 1 1 2 2 2 2 H2C2 zinc finger RT_RNaseH PF17917.1 GBG72207.1 - 0.00032 20.9 0.0 0.00064 20.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CCSAP PF15748.5 GBG72208.1 - 0.12 12.6 17.3 0.12 12.5 17.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CobT PF06213.12 GBG72208.1 - 0.36 10.2 31.2 0.45 9.9 31.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Vfa1 PF08432.10 GBG72208.1 - 0.52 10.6 20.0 0.66 10.3 20.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FGF-BP1 PF06473.12 GBG72208.1 - 0.9 9.3 13.1 1 9.1 13.1 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Nop14 PF04147.12 GBG72208.1 - 1.2 7.2 34.2 1.4 7.0 34.2 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG72208.1 - 1.7 7.0 36.5 1.9 6.8 36.5 1.0 1 0 0 1 1 1 0 Mpp10 protein SLC12 PF03522.15 GBG72208.1 - 4 6.4 10.4 3.8 6.4 10.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 GBG72208.1 - 7.1 5.3 15.5 7.8 5.1 15.5 1.0 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 GBG72208.1 - 7.6 5.2 20.3 8.5 5.0 20.3 1.0 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 GBG72208.1 - 9.1 5.1 11.2 10 4.9 11.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Senescence_reg PF04520.13 GBG72209.1 - 5.7e-15 56.6 0.0 1.3e-14 55.4 0.0 1.6 2 0 0 2 2 2 1 Senescence regulator PalH PF08733.10 GBG72210.1 - 1.6 7.7 6.8 2.3 7.1 6.8 1.1 1 0 0 1 1 1 0 PalH/RIM21 SNN_linker PF09050.10 GBG72211.1 - 0.14 12.0 6.0 2.2 8.1 0.1 3.1 2 0 0 2 2 2 0 Stannin unstructured linker GDP_Man_Dehyd PF16363.5 GBG72212.1 - 1.1e-60 205.8 0.0 2.6e-60 204.6 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG72212.1 - 1.1e-46 159.2 0.0 1.4e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GBG72212.1 - 3.8e-13 49.1 0.0 8e-13 48.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GBG72212.1 - 4.5e-13 49.0 0.0 8.6e-08 31.7 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 GBG72212.1 - 1e-08 34.7 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GBG72212.1 - 1.6e-08 34.1 0.1 2.1e-07 30.4 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 GBG72212.1 - 0.0042 16.6 0.0 0.019 14.4 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_10 PF13460.6 GBG72212.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 GBG72212.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 KR domain TrkA_N PF02254.18 GBG72212.1 - 0.14 12.5 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NPF PF16601.5 GBG72214.1 - 0.21 12.0 3.8 0.47 10.9 3.8 1.5 1 0 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif RT_RNaseH_2 PF17919.1 GBG72215.1 - 1.4e-16 60.3 0.0 2.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72215.1 - 7.2e-15 54.8 0.1 2e-14 53.4 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG72215.1 - 2.6e-14 53.4 0.0 8.7e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72215.1 - 2.3e-13 50.4 0.0 5.4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG72215.1 - 1.1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG72215.1 - 0.0081 15.9 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain GDP_Man_Dehyd PF16363.5 GBG72216.1 - 2.4e-50 171.8 0.0 3.5e-43 148.3 0.0 2.1 1 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG72216.1 - 1.8e-36 125.8 0.0 2.3e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GBG72216.1 - 1.4e-12 47.3 0.1 4.7e-07 29.3 0.0 2.6 1 1 2 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 GBG72216.1 - 4.5e-12 45.6 0.0 6.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GBG72216.1 - 2.3e-07 30.2 0.0 1.6e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GBG72216.1 - 3.5e-07 29.7 0.2 2.4e-06 26.9 0.2 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 GBG72216.1 - 0.0067 15.9 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 GBG72216.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 GBG72216.1 - 0.039 13.9 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 KR domain TrkA_N PF02254.18 GBG72216.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.23 GBG72217.1 - 5.9e-47 159.3 0.1 9.8e-47 158.6 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 GBG72217.1 - 1.2e-46 158.7 0.0 2.3e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 GBG72217.1 - 7.6e-05 21.8 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 GBG72217.1 - 0.027 13.8 0.0 0.1 11.9 0.0 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 GBG72217.1 - 0.076 12.9 0.2 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H-binding TMEM192 PF14802.6 GBG72218.1 - 1.1 8.4 2.9 2.1 7.4 2.9 1.5 1 0 0 1 1 1 0 TMEM192 family PikAIV_N PF18605.1 GBG72218.1 - 5.8 6.6 12.5 7.4 6.2 1.7 4.3 4 0 0 4 4 4 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain RRM_1 PF00076.22 GBG72219.1 - 6.5e-14 51.5 0.0 7.4e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GBG72220.1 - 1.2e-15 57.1 0.0 2e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GBG72220.1 - 0.052 13.6 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 RNA binding motif Med20 PF08612.11 GBG72221.1 - 1.4e-29 103.1 0.0 1.8e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex RRM_1 PF00076.22 GBG72222.1 - 1.2e-11 44.3 0.0 3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 GBG72222.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RL domain Myb_DNA-bind_4 PF13837.6 GBG72223.1 - 1.1e-05 25.7 0.8 2.3e-05 24.7 0.8 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG72224.1 - 2e-08 34.5 0.6 3.9e-07 30.3 0.4 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain CLZ PF16526.5 GBG72227.1 - 0.0085 16.4 7.2 0.24 11.8 0.9 2.8 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF745 PF05335.13 GBG72227.1 - 0.012 15.3 4.9 0.022 14.5 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) IFT57 PF10498.9 GBG72227.1 - 0.02 13.8 8.5 0.028 13.4 8.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.9 GBG72227.1 - 0.026 14.8 4.2 0.14 12.5 0.3 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup88 PF10168.9 GBG72227.1 - 0.077 10.8 9.3 0.089 10.6 9.3 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF724 PF05266.14 GBG72227.1 - 0.093 12.5 9.7 0.086 12.7 7.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Laminin_II PF06009.12 GBG72227.1 - 0.097 12.7 2.8 0.13 12.3 2.0 1.6 1 1 0 1 1 1 0 Laminin Domain II TPR_MLP1_2 PF07926.12 GBG72227.1 - 0.1 12.7 13.8 0.21 11.7 13.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 GBG72227.1 - 0.12 12.4 19.6 0.049 13.7 15.7 2.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 GBG72227.1 - 0.19 11.0 13.4 0.31 10.4 13.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 GBG72227.1 - 0.23 9.3 5.9 0.29 9.0 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 GBG72227.1 - 0.36 9.4 4.0 0.47 9.0 4.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc24 PF08286.11 GBG72227.1 - 1.9 8.8 8.1 5.3 7.3 1.9 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 GrpE PF01025.19 GBG72227.1 - 1.9 8.1 14.8 1.3 8.7 3.1 2.3 1 1 1 2 2 2 0 GrpE APG6_N PF17675.1 GBG72227.1 - 2.9 8.4 23.9 1.5 9.3 4.7 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 GBG72227.1 - 3.7 7.6 13.6 3.6 7.6 3.9 2.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding IFT20 PF14931.6 GBG72227.1 - 4.9 7.3 11.5 0.23 11.6 3.2 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 TMPIT PF07851.13 GBG72227.1 - 9.2 5.4 7.2 13 4.9 7.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein UCH PF00443.29 GBG72228.1 - 6.4e-58 196.2 0.1 2e-57 194.6 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG72228.1 - 3.4e-28 99.2 0.1 1.5e-27 97.0 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SAPS PF04499.15 GBG72229.1 - 0.34 9.7 1.5 0.51 9.0 1.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DEAD PF00270.29 GBG72231.1 - 4.3e-42 143.8 0.0 7.4e-40 136.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG72231.1 - 0.00046 20.5 0.0 0.032 14.6 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Thg1 PF04446.12 GBG72232.1 - 9.2e-51 171.1 0.0 1.4e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 GBG72232.1 - 1.5e-44 151.0 14.1 2.3e-43 147.3 4.8 2.3 1 1 1 2 2 2 2 Thg1 C terminal domain TFB6 PF17110.5 GBG72232.1 - 0.001 18.8 4.8 0.0017 18.1 4.8 1.4 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH AIF_C PF14721.6 GBG72232.1 - 0.0032 17.8 3.3 0.0047 17.3 3.3 1.2 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pox_Ag35 PF03286.14 GBG72232.1 - 0.0043 16.9 13.8 0.0064 16.3 13.8 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein SpoIIP PF07454.11 GBG72232.1 - 0.013 14.9 9.2 0.018 14.5 9.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 GBG72232.1 - 0.015 15.5 6.5 0.022 14.9 6.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Afi1 PF07792.12 GBG72232.1 - 0.016 15.7 5.7 0.025 15.1 5.7 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Connexin PF00029.19 GBG72232.1 - 0.017 14.9 7.9 0.017 14.9 7.9 1.6 2 0 0 2 2 1 0 Connexin SID-1_RNA_chan PF13965.6 GBG72232.1 - 0.022 13.2 0.4 0.025 13.0 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 GBG72232.1 - 0.022 14.6 14.6 0.028 14.2 14.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG72232.1 - 0.046 12.5 5.3 0.063 12.0 5.3 1.2 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 GBG72232.1 - 0.047 13.8 1.8 0.063 13.4 1.8 1.2 1 0 0 1 1 1 0 DDHD domain DUF2052 PF09747.9 GBG72232.1 - 0.077 13.1 19.0 0.12 12.5 19.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) dsRBD2 PF17842.1 GBG72232.1 - 0.078 13.2 9.0 0.47 10.6 8.9 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 AAA_11 PF13086.6 GBG72232.1 - 0.09 12.5 4.7 0.12 12.2 4.7 1.2 1 0 0 1 1 1 0 AAA domain DUF913 PF06025.12 GBG72232.1 - 0.16 10.9 5.1 0.2 10.6 5.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_polI_A34 PF08208.11 GBG72232.1 - 0.29 11.2 26.0 0.44 10.6 26.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 BUD22 PF09073.10 GBG72232.1 - 0.31 10.4 20.7 0.4 10.0 20.7 1.1 1 0 0 1 1 1 0 BUD22 AFT PF08731.11 GBG72232.1 - 0.39 11.1 8.3 0.75 10.2 8.3 1.4 1 0 0 1 1 1 0 Transcription factor AFT RNA_pol_Rpc4 PF05132.14 GBG72232.1 - 0.6 10.5 11.4 0.93 9.9 11.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4746 PF15928.5 GBG72232.1 - 0.64 9.4 19.5 1 8.7 19.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Fmp27 PF10344.9 GBG72232.1 - 0.64 8.0 6.6 0.78 7.8 6.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Bud13 PF09736.9 GBG72232.1 - 0.67 10.3 19.4 1 9.8 19.4 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex NARP1 PF12569.8 GBG72232.1 - 0.7 8.7 19.8 0.99 8.2 19.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 V_ATPase_I PF01496.19 GBG72232.1 - 0.73 7.7 10.0 1 7.2 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TLP-20 PF06088.11 GBG72232.1 - 0.76 9.6 8.7 1.3 8.9 8.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RNA_pol_3_Rpc31 PF11705.8 GBG72232.1 - 0.82 9.9 22.1 1.1 9.4 22.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RPA43_OB PF17875.1 GBG72232.1 - 0.89 10.2 8.3 1.6 9.4 8.3 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I NPR3 PF03666.13 GBG72232.1 - 0.89 8.3 9.8 1.4 7.6 9.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 GBG72232.1 - 0.96 8.8 20.7 1.4 8.3 20.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 GBG72232.1 - 1 8.5 11.3 1.6 7.8 11.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Eapp_C PF10238.9 GBG72232.1 - 1.1 9.3 11.7 3.2 7.8 11.7 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein Neur_chan_memb PF02932.16 GBG72232.1 - 1.2 9.1 4.7 0.28 11.2 1.7 1.5 2 0 0 2 2 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2828 PF11443.8 GBG72232.1 - 1.2 7.1 9.9 1.6 6.7 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CDC45 PF02724.14 GBG72232.1 - 1.3 7.3 18.0 1.7 6.8 18.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 GBG72232.1 - 1.5 9.1 21.0 2.5 8.4 21.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDRGK PF09756.9 GBG72232.1 - 1.9 8.1 32.7 2.9 7.4 32.7 1.2 1 0 0 1 1 1 0 DDRGK domain PTPRCAP PF15713.5 GBG72232.1 - 2 8.7 19.6 2.9 8.2 19.6 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4820 PF16091.5 GBG72232.1 - 3 7.2 9.4 4.5 6.6 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CLN3 PF02487.17 GBG72232.1 - 4.1 6.3 6.3 5.9 5.8 6.3 1.1 1 0 0 1 1 1 0 CLN3 protein Astro_capsid_p PF12226.8 GBG72232.1 - 4.3 6.4 11.7 8 5.5 11.7 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Ureide_permease PF07168.11 GBG72232.1 - 4.5 5.9 4.5 6.4 5.4 4.5 1.2 1 0 0 1 1 1 0 Ureide permease MDM10 PF12519.8 GBG72232.1 - 5 5.9 8.1 6.6 5.5 8.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4637 PF15470.6 GBG72232.1 - 5.7 6.6 24.0 10 5.8 24.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Zip PF02535.22 GBG72232.1 - 5.8 6.0 9.1 9.8 5.3 9.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FancD2 PF14631.6 GBG72232.1 - 6.3 4.1 10.8 8.1 3.7 10.8 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Merozoite_SPAM PF07133.11 GBG72232.1 - 7.1 6.6 40.6 12 5.9 40.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DNA_pol_phi PF04931.13 GBG72232.1 - 7.4 4.5 27.2 9.9 4.1 27.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Tim54 PF11711.8 GBG72232.1 - 7.6 5.2 17.7 11 4.7 17.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YqfQ PF14181.6 GBG72232.1 - 8.9 6.5 11.4 14 5.9 11.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein BUD22 PF09073.10 GBG72233.1 - 0.43 9.9 27.2 0.52 9.6 27.2 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG72233.1 - 0.51 8.5 27.8 0.63 8.2 27.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 GBG72233.1 - 0.7 9.0 28.5 0.99 8.5 28.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Raftlin PF15250.6 GBG72233.1 - 1.1 7.9 8.0 1.4 7.6 8.0 1.2 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.12 GBG72233.1 - 1.2 8.5 27.7 1.8 7.9 27.7 1.3 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.7 GBG72233.1 - 2.6 6.1 10.2 3.2 5.8 10.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.11 GBG72233.1 - 4 6.8 6.7 4.7 6.5 6.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein V_ATPase_I PF01496.19 GBG72233.1 - 5 4.9 4.8 5.4 4.8 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SURF2 PF05477.11 GBG72233.1 - 5.1 6.7 14.5 6.7 6.3 14.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PPP4R2 PF09184.11 GBG72233.1 - 8.1 5.9 20.8 12 5.3 20.8 1.4 1 0 0 1 1 1 0 PPP4R2 RVT_1 PF00078.27 GBG72234.1 - 2e-11 43.9 0.0 2.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG72234.1 - 0.046 13.1 23.2 0.06 12.7 23.2 1.1 1 0 0 1 1 1 0 BUD22 DUF572 PF04502.13 GBG72234.1 - 0.088 12.4 10.7 0.12 12.0 10.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2457 PF10446.9 GBG72234.1 - 1 8.4 28.5 1.5 7.9 28.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Raftlin PF15250.6 GBG72234.1 - 3.2 6.4 8.1 4.2 6.0 8.1 1.2 1 0 0 1 1 1 0 Raftlin RPN2_C PF18004.1 GBG72234.1 - 3.9 7.4 13.8 7.5 6.5 13.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SDA1 PF05285.12 GBG72234.1 - 4.1 6.7 28.7 6.1 6.2 28.7 1.2 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.7 GBG72234.1 - 6.9 4.7 11.1 9.4 4.2 11.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 GBG72234.1 - 8.8 4.4 30.8 11 4.1 30.8 1.1 1 0 0 1 1 1 0 Nop14-like family HD_6 PF18019.1 GBG72235.1 - 0.048 13.8 0.4 0.071 13.2 0.4 1.4 1 0 0 1 1 1 0 HD domain DUF2457 PF10446.9 GBG72235.1 - 0.51 9.4 28.5 0.74 8.9 28.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 GBG72235.1 - 0.61 9.5 27.2 0.86 9.0 27.2 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG72235.1 - 1.4 7.0 29.4 1.7 6.8 29.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG72235.1 - 2.1 8.0 21.6 3.2 7.4 21.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GBG72235.1 - 7.2 5.8 31.2 9 5.5 31.2 1.1 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.7 GBG72235.1 - 7.3 4.6 11.8 8.6 4.3 11.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RINGv PF12906.7 GBG72236.1 - 2.9e-06 27.3 0.9 2.9e-06 27.3 0.9 2.6 2 0 0 2 2 2 1 RING-variant domain zf-RING-like PF08746.11 GBG72236.1 - 1.5 9.2 6.5 0.17 12.2 1.0 2.2 2 0 0 2 2 2 0 RING-like domain UBA PF00627.31 GBG72237.1 - 5.6e-10 38.9 0.1 9e-10 38.3 0.1 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 GBG72237.1 - 0.00046 20.2 7.0 0.00071 19.6 7.0 1.4 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.15 GBG72237.1 - 0.014 15.3 0.3 0.023 14.6 0.3 1.3 1 0 0 1 1 1 0 Der1-like family CUE PF02845.16 GBG72237.1 - 0.015 15.0 0.2 0.041 13.6 0.2 1.7 1 0 0 1 1 1 0 CUE domain UBA_3 PF09288.10 GBG72237.1 - 0.022 14.6 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Retrotrans_gag PF03732.17 GBG72238.1 - 0.00019 21.6 0.2 0.00019 21.6 0.2 2.9 4 0 0 4 4 4 1 Retrotransposon gag protein Baculo_PEP_C PF04513.12 GBG72238.1 - 0.14 12.2 6.6 0.41 10.7 6.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4205 PF13898.6 GBG72240.1 - 5.2e-61 206.5 0.0 8.2e-58 196.0 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) RVT_1 PF00078.27 GBG72241.1 - 1.5e-21 76.9 3.2 1.7e-21 76.8 0.3 2.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG72241.1 - 0.021 15.1 9.4 0.09 13.1 0.0 5.2 4 1 1 5 5 5 0 Retrotransposon gag protein EMP70 PF02990.16 GBG72242.1 - 1.1e-222 740.4 12.3 1.1e-222 740.4 12.3 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 Peptidase_A24 PF01478.18 GBG72242.1 - 0.095 13.1 0.4 0.095 13.1 0.4 4.4 3 2 1 4 4 4 0 Type IV leader peptidase family CopD PF05425.13 GBG72242.1 - 5.8 7.4 19.9 0.029 14.7 3.3 4.2 4 1 0 5 5 5 0 Copper resistance protein D RRM_1 PF00076.22 GBG72243.1 - 1.1e-16 60.4 0.0 1.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop53 PF07767.11 GBG72243.1 - 0.02 14.3 0.3 0.025 14.0 0.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RRM_5 PF13893.6 GBG72243.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF724 PF05266.14 GBG72243.1 - 0.043 13.6 3.0 0.064 13.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) EMP24_GP25L PF01105.24 GBG72243.1 - 0.82 9.6 2.9 1.2 9.0 2.9 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SOGA PF11365.8 GBG72243.1 - 0.82 10.8 6.4 1.2 10.3 5.3 1.8 1 1 1 2 2 2 0 Protein SOGA zf-U11-48K PF05253.12 GBG72246.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger DUF3242 PF11586.8 GBG72246.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) HAD_2 PF13419.6 GBG72247.1 - 9.7e-17 61.6 0.0 2.5e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GBG72247.1 - 2.7e-11 44.1 0.0 2.8e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG72247.1 - 2.1e-08 34.1 0.0 4.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GBG72247.1 - 0.0095 16.4 0.1 0.015 15.7 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase tRNA-synt_2e PF02091.15 GBG72247.1 - 0.087 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit Zip PF02535.22 GBG72249.1 - 0.11 11.7 1.2 0.098 11.9 1.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 GBG72249.1 - 0.16 11.4 9.9 0.17 11.3 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 GBG72249.1 - 0.27 9.4 32.8 0.29 9.3 32.8 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG72249.1 - 0.41 10.0 34.8 0.51 9.7 34.8 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 GBG72249.1 - 0.85 9.0 24.3 1 8.7 24.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 GBG72249.1 - 0.94 8.4 5.2 0.94 8.4 5.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 GBG72249.1 - 1.1 7.1 3.4 0.93 7.3 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RPN2_C PF18004.1 GBG72249.1 - 1.1 9.2 9.8 1.4 8.8 9.8 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 GBG72249.1 - 1.6 7.0 23.5 1.7 6.8 23.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Pes-10 PF07149.11 GBG72249.1 - 1.7 7.6 27.6 1.9 7.5 27.6 1.2 1 0 0 1 1 1 0 Pes-10 DUF2428 PF10350.9 GBG72249.1 - 5.7 6.1 5.7 6.2 6.0 5.7 1.2 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Mpp10 PF04006.12 GBG72249.1 - 7 5.0 27.9 7.8 4.8 27.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Utp14 PF04615.13 GBG72249.1 - 8 4.9 23.8 9.6 4.6 23.8 1.0 1 0 0 1 1 1 0 Utp14 protein THOC2_N PF16134.5 GBG72249.1 - 9.3 4.7 8.1 9.3 4.7 8.1 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF659 PF04937.15 GBG72250.1 - 1.7e-33 115.7 0.0 2.5e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG72250.1 - 1.2e-08 34.6 0.2 2.5e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Cwf_Cwc_15 PF04889.12 GBG72250.1 - 0.18 11.6 3.2 0.41 10.3 3.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 GBG72251.1 - 0.00016 21.8 43.8 0.00031 20.9 43.8 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit HAUS6_N PF14661.6 GBG72251.1 - 0.001 18.7 11.2 0.001 18.7 11.2 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus DUF2052 PF09747.9 GBG72251.1 - 0.15 12.2 30.8 0.038 14.1 5.2 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PAT1 PF09770.9 GBG72251.1 - 0.15 10.3 29.9 0.33 9.2 29.9 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 GBG72251.1 - 0.15 11.8 26.3 0.59 9.9 15.0 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PTPRCAP PF15713.5 GBG72251.1 - 0.43 10.9 38.8 0.18 12.1 8.4 2.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF2347 PF09804.9 GBG72251.1 - 1.4 8.4 6.9 1.1e+02 2.2 8.4 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Med15 PF09606.10 GBG72251.1 - 1.6 7.3 40.4 2.5 6.7 40.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Zip PF02535.22 GBG72251.1 - 1.7 7.8 15.8 3.5 6.8 10.6 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.17 GBG72251.1 - 1.8 7.2 27.2 0.55 8.9 18.1 2.2 2 0 0 2 2 2 0 Presenilin RNA_pol_Rpc4 PF05132.14 GBG72251.1 - 2.2 8.7 18.7 1.5 9.2 7.8 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 GBG72251.1 - 3.1 8.0 21.6 4.4 7.5 1.4 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 GBG72251.1 - 8.3 6.8 24.9 12 6.2 0.2 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like zf-RNPHF PF08080.12 GBG72252.1 - 0.51 10.3 8.5 0.1 12.6 1.1 3.6 2 1 1 3 3 3 0 RNPHF zinc finger Sel1 PF08238.12 GBG72253.1 - 0 977.5 202.6 5.5e-12 45.9 0.9 36.8 37 1 0 37 37 37 36 Sel1 repeat TPR_6 PF13174.6 GBG72253.1 - 6.8e-06 26.4 45.6 0.19 12.4 0.1 18.0 23 1 1 24 24 24 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG72253.1 - 0.028 14.8 27.2 30 5.3 0.0 14.5 18 1 0 18 18 18 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG72253.1 - 0.075 13.1 33.0 0.12 12.5 0.1 13.3 13 2 2 15 15 15 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG72253.1 - 0.33 11.6 114.5 0.28 11.9 3.6 19.0 14 7 9 23 23 23 0 Tetratricopeptide repeat CDC45 PF02724.14 GBG72254.1 - 6.7 4.9 9.1 7 4.8 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NUC173 PF08161.12 GBG72256.1 - 1.6e-52 178.1 8.2 7.7e-48 162.9 0.1 4.6 4 1 1 5 5 5 3 NUC173 domain MMS19_C PF12460.8 GBG72256.1 - 0.0021 17.3 2.0 0.043 12.9 0.6 3.4 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 GBG72256.1 - 0.0087 16.6 0.1 0.14 12.7 0.0 3.2 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 GBG72256.1 - 1.2 9.8 0.0 1.2 9.8 0.0 5.1 7 1 1 8 8 8 0 HEAT-like repeat Laminin_II PF06009.12 GBG72257.1 - 0.0017 18.4 3.5 0.0017 18.4 3.5 2.4 2 1 1 3 3 3 1 Laminin Domain II HsbA PF12296.8 GBG72257.1 - 0.012 16.0 5.5 0.015 15.7 1.0 2.2 1 1 1 2 2 2 0 Hydrophobic surface binding protein A DUF948 PF06103.11 GBG72257.1 - 0.025 14.8 10.5 0.025 14.8 10.5 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 GBG72257.1 - 0.028 14.4 1.7 0.38 10.8 0.2 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.21 GBG72257.1 - 0.029 14.2 7.2 0.095 12.5 4.8 2.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain YkyA PF10368.9 GBG72257.1 - 0.037 13.7 1.8 4.2 7.0 0.0 2.6 2 1 1 3 3 3 0 Putative cell-wall binding lipoprotein DASH_Duo1 PF08651.10 GBG72257.1 - 0.17 11.7 0.0 16 5.3 0.0 2.6 1 1 2 3 3 3 0 DASH complex subunit Duo1 ApoLp-III PF07464.11 GBG72257.1 - 0.25 11.5 5.8 0.36 10.9 1.8 2.5 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 GBG72257.1 - 1.1 10.0 3.9 25 5.6 2.4 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YlbD_coat PF14071.6 GBG72257.1 - 4.5 7.6 6.3 1e+02 3.2 5.7 2.5 1 1 0 1 1 1 0 Putative coat protein Cauli_AT PF03233.13 GBG72257.1 - 4.7 7.1 4.4 1.5 8.8 0.8 1.9 2 1 0 2 2 2 0 Aphid transmission protein YtxH PF12732.7 GBG72257.1 - 6.1 7.5 18.6 1.7e+04 -3.6 18.6 3.5 1 1 0 1 1 0 0 YtxH-like protein E2F_CC-MB PF16421.5 GBG72260.1 - 0.4 11.1 3.7 1.1 9.7 0.1 2.6 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain ORC_WH_C PF18137.1 GBG72260.1 - 7.2 6.7 12.2 0.96 9.5 1.0 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal RT_RNaseH_2 PF17919.1 GBG72261.1 - 1.8e-31 108.1 0.0 5.4e-31 106.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72261.1 - 2.6e-28 99.1 0.0 4.2e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72261.1 - 1.7e-23 82.9 0.0 4e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Metallophos PF00149.28 GBG72262.1 - 0.00024 21.7 0.0 0.00083 19.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ndc1_Nup PF09531.10 GBG72263.1 - 8e-23 81.0 1.9 1e-17 64.1 0.4 2.6 2 1 1 3 3 3 2 Nucleoporin protein Ndc1-Nup Serglycin PF04360.12 GBG72265.1 - 1.3 9.0 7.8 1.7 8.6 4.3 2.0 2 0 0 2 2 2 0 Serglycin Glyco_transf_8 PF01501.20 GBG72266.1 - 3.3e-80 269.3 2.7 3.3e-80 269.3 2.7 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GBG72266.1 - 0.0088 15.5 0.4 0.0088 15.5 0.4 1.6 1 1 0 2 2 2 1 Glucosyltransferase 24 RVT_1 PF00078.27 GBG72267.1 - 9.9e-15 54.6 0.1 1.3e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG72267.1 - 0.05 12.9 22.3 0.064 12.6 22.3 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG72267.1 - 0.075 11.3 15.8 0.1 10.9 15.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG72267.1 - 0.11 10.7 22.9 0.14 10.3 22.9 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG72267.1 - 0.12 11.8 21.8 0.15 11.5 21.8 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG72267.1 - 0.15 11.6 9.5 0.21 11.1 9.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NPR3 PF03666.13 GBG72267.1 - 0.52 9.0 3.2 0.66 8.7 3.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LAP1C PF05609.12 GBG72267.1 - 0.55 9.3 7.9 0.65 9.0 7.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 GBG72267.1 - 2.1 7.0 9.7 2.9 6.6 9.7 1.2 1 0 0 1 1 1 0 Presenilin Smg8_Smg9 PF10220.9 GBG72267.1 - 2.5 6.3 7.7 3.3 5.9 7.7 1.1 1 0 0 1 1 1 0 Smg8_Smg9 RR_TM4-6 PF06459.12 GBG72267.1 - 5.9 6.6 17.2 9.1 6.0 17.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_8 PF01501.20 GBG72268.1 - 2e-85 286.4 2.3 2.9e-85 285.9 2.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GBG72268.1 - 0.00049 19.6 0.1 0.00089 18.7 0.1 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_transf_8 PF01501.20 GBG72269.1 - 2e-85 286.4 2.3 3e-85 285.9 2.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GBG72269.1 - 0.00049 19.6 0.1 0.00089 18.7 0.1 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 BLM10_mid PF16507.5 GBG72270.1 - 0.00089 18.0 0.6 0.0038 16.0 0.0 2.0 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region FUSC PF04632.12 GBG72270.1 - 0.0025 16.4 0.4 0.0025 16.4 0.4 2.1 2 1 0 2 2 2 1 Fusaric acid resistance protein family MacB_PCD PF12704.7 GBG72270.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 MacB-like periplasmic core domain AAA_23 PF13476.6 GBG72270.1 - 1.2 9.6 14.9 2.3 8.7 14.9 1.5 1 0 0 1 1 1 0 AAA domain EF-hand_14 PF17959.1 GBG72270.1 - 1.3 9.5 4.9 2.9 8.3 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain Zip PF02535.22 GBG72270.1 - 9.4 5.3 7.3 5.1 6.2 4.6 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter AUDH_Cupin PF18637.1 GBG72271.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain RVT_1 PF00078.27 GBG72272.1 - 4.7e-76 255.2 0.5 4.5e-38 131.0 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72272.1 - 4.4e-31 106.9 0.0 1.2e-30 105.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72272.1 - 1.3e-30 105.8 0.1 4.2e-30 104.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HisKA PF00512.25 GBG72272.1 - 2.5e-16 59.5 4.5 3.2e-16 59.1 0.0 3.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Integrase_H2C2 PF17921.1 GBG72272.1 - 5.8e-10 39.1 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG72272.1 - 2.5e-05 24.8 0.0 7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG72272.1 - 8.7e-05 22.3 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG72272.1 - 0.0011 19.5 0.0 0.0036 17.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG72272.1 - 0.0028 17.4 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gpUL132 PF11359.8 GBG72272.1 - 0.075 12.6 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 Phage_GPO PF05929.11 GBG72272.1 - 0.078 12.6 0.0 0.078 12.6 0.0 3.1 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Response_reg PF00072.24 GBG72274.1 - 6.7e-25 87.4 0.5 3.3e-24 85.2 0.0 2.5 3 0 0 3 3 2 1 Response regulator receiver domain HATPase_c PF02518.26 GBG72274.1 - 5.1e-18 65.6 0.4 1.1e-17 64.6 0.4 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RVP_2 PF08284.11 GBG72274.1 - 3.4e-11 43.0 0.0 7.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG72274.1 - 9e-09 35.2 0.0 2.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG72274.1 - 9.8e-09 35.7 0.0 2.9e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72274.1 - 2e-06 28.3 0.0 6.4e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG72274.1 - 0.00073 19.8 0.4 0.0025 18.1 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein RVP PF00077.20 GBG72274.1 - 0.0037 17.6 0.0 0.22 11.9 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72274.1 - 0.0092 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RA PF00788.23 GBG72274.1 - 0.14 12.8 0.1 0.37 11.4 0.1 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain DUF1758 PF05585.12 GBG72274.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) HATPase_c PF02518.26 GBG72275.1 - 5e-18 65.7 0.4 1e-17 64.7 0.4 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RVP_2 PF08284.11 GBG72275.1 - 3.3e-11 43.1 0.0 6.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG72275.1 - 9.1e-09 35.2 0.0 2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG72275.1 - 9.4e-09 35.8 0.0 2.8e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Response_reg PF00072.24 GBG72275.1 - 1.5e-07 31.5 0.4 9.1e-07 29.0 0.0 2.6 3 0 0 3 3 3 1 Response regulator receiver domain gag-asp_proteas PF13975.6 GBG72275.1 - 1.9e-06 28.3 0.0 6.1e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG72275.1 - 0.00071 19.8 0.5 0.0024 18.1 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein RVP PF00077.20 GBG72275.1 - 0.0033 17.7 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72275.1 - 0.0088 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG72275.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) IBR PF01485.21 GBG72276.1 - 1.1e-24 86.4 19.6 3.6e-17 62.4 5.1 4.9 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 GBG72276.1 - 2.2e-05 24.4 31.1 0.014 15.5 0.7 4.4 3 1 0 3 3 3 2 RING-type zinc-finger zf-RanBP PF00641.18 GBG72276.1 - 0.00016 20.9 0.4 0.00016 20.9 0.4 3.0 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others zf-C3HC4_2 PF13923.6 GBG72276.1 - 0.0014 18.4 4.3 0.0014 18.4 4.3 5.5 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG72276.1 - 0.0018 18.1 9.5 0.0046 16.8 1.2 5.8 4 2 2 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG72276.1 - 0.0065 16.8 41.9 0.47 10.8 10.0 4.8 2 2 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 GBG72276.1 - 0.015 15.3 3.4 0.015 15.3 3.4 5.5 4 2 1 5 5 5 0 zinc-RING finger domain HTS PF04204.16 GBG72276.1 - 0.05 12.5 0.2 0.17 10.8 0.1 1.8 1 1 1 2 2 2 0 Homoserine O-succinyltransferase RVT_1 PF00078.27 GBG72279.1 - 1e-27 97.1 0.1 1.6e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG72279.1 - 2.3e-10 40.2 0.0 5.8e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG72279.1 - 2.5e-08 34.2 0.0 1.2e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG72280.1 - 5.2e-85 284.5 0.0 8.8e-32 110.4 0.0 3.5 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72280.1 - 4.1e-51 171.2 0.0 2.2e-26 91.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72280.1 - 8.1e-48 161.1 0.0 9e-24 83.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72280.1 - 1.8e-18 66.4 0.2 5.6e-18 64.8 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72280.1 - 3e-09 37.1 0.0 8.9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72280.1 - 0.0058 16.8 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger ST7 PF04184.12 GBG72280.1 - 0.056 11.9 0.6 2.3 6.6 0.1 2.2 2 0 0 2 2 2 0 ST7 protein DUF2202 PF09968.9 GBG72280.1 - 0.071 13.0 0.1 5.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) Integrin_b_cyt PF08725.11 GBG72280.1 - 0.1 12.3 0.0 18 5.1 0.0 2.6 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain zf-CCHC PF00098.23 GBG72281.1 - 3.7e-06 26.7 3.3 6.1e-06 26.1 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG72281.1 - 0.0032 17.4 3.9 0.0071 16.3 3.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG72281.1 - 0.42 10.4 3.5 0.22 11.3 1.0 1.7 2 0 0 2 2 2 0 Zinc knuckle OAM_dimer PF16554.5 GBG72282.1 - 0.11 12.9 0.9 0.26 11.8 0.9 1.6 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase Pex24p PF06398.11 GBG72282.1 - 0.32 9.9 3.5 0.45 9.4 3.5 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin AP1AR PF15745.5 GBG72282.1 - 0.51 9.9 15.4 0.84 9.2 15.4 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein TPR_2 PF07719.17 GBG72284.1 - 1.6e-19 68.4 0.1 6.3e-05 22.8 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG72284.1 - 3.3e-19 67.8 0.0 2e-05 24.2 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 GBG72284.1 - 3.7e-16 59.5 0.8 1.3e-07 32.2 0.5 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG72284.1 - 4.4e-15 55.1 0.0 6.8e-06 25.7 0.0 3.7 2 2 2 4 4 4 3 TPR repeat TPR_14 PF13428.6 GBG72284.1 - 3.2e-14 52.4 4.0 0.0033 18.1 0.0 4.9 2 1 3 5 5 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 GBG72284.1 - 9.4e-14 51.5 0.2 1.2e-08 35.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG72284.1 - 5.1e-13 48.1 0.0 0.0014 18.7 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GBG72284.1 - 1.3e-12 47.1 0.1 2.8e-05 24.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG72284.1 - 1.4e-09 37.2 1.1 0.014 15.3 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG72284.1 - 8.1e-09 35.9 9.1 0.00037 20.9 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG72284.1 - 3.9e-07 29.7 8.7 0.0078 16.1 0.2 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG72284.1 - 7.4e-07 29.2 0.5 0.0024 18.0 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG72284.1 - 2.9e-06 26.9 2.9 0.00071 19.1 0.4 1.7 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 GBG72284.1 - 1.1e-05 25.6 0.6 0.23 12.2 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG72284.1 - 0.00022 21.4 0.0 0.00066 19.9 0.0 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GBG72284.1 - 0.0011 19.4 0.2 8.2 7.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 GBG72284.1 - 0.004 16.4 0.2 0.65 9.2 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat Asp4 PF16996.5 GBG72284.1 - 0.063 13.1 0.1 0.29 11.0 0.0 2.1 3 0 0 3 3 3 0 Accessory secretory protein Sec Asp4 DUF4281 PF14108.6 GBG72284.1 - 0.084 13.2 0.1 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) TPR_20 PF14561.6 GBG72284.1 - 0.42 11.0 7.3 4.8 7.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SDA1 PF05285.12 GBG72285.1 - 1.2 8.5 26.5 2.1 7.7 26.5 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG72285.1 - 2.8 6.0 28.7 4 5.5 28.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF659 PF04937.15 GBG72286.1 - 9.5e-29 100.2 0.5 1.5e-28 99.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG72286.1 - 0.00045 20.0 0.2 0.0015 18.3 0.1 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region acVLRF1 PF18859.1 GBG72287.1 - 0.051 13.9 0.1 0.074 13.3 0.1 1.3 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor Myb_DNA-bind_4 PF13837.6 GBG72288.1 - 4.4e-06 27.0 0.9 7.9e-06 26.2 0.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG72288.1 - 0.0028 17.7 0.3 0.0045 17.0 0.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG72288.1 - 0.11 12.7 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain RT_RNaseH PF17917.1 GBG72289.1 - 5.2e-21 74.9 0.0 2.5e-20 72.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72289.1 - 4.4e-20 71.6 0.0 1.3e-19 70.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72289.1 - 3.2e-11 43.1 0.0 8.9e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG72289.1 - 0.00015 21.3 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PheRS_DBD2 PF18554.1 GBG72290.1 - 0.067 13.2 0.9 0.17 11.9 0.2 2.1 2 0 0 2 2 2 0 PheRS DNA binding domain 2 ECH_2 PF16113.5 GBG72291.1 - 2.9e-122 408.3 0.1 4.9e-88 295.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GBG72291.1 - 8.6e-22 77.7 0.0 1.4e-13 50.8 0.0 2.6 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase CAP_N PF01213.19 GBG72291.1 - 2.3 7.6 6.3 5.4 6.4 6.3 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RVT_1 PF00078.27 GBG72292.1 - 8e-30 104.0 0.0 1.4e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG72292.1 - 1e-08 35.0 0.0 1.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L28 PF00830.19 GBG72293.1 - 0.042 14.0 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L28 family DsbD_2 PF13386.6 GBG72294.1 - 0.002 18.1 11.5 0.002 18.1 11.5 2.7 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region DUF2583 PF10762.9 GBG72294.1 - 0.21 12.0 4.0 0.34 11.4 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) Dimer_Tnp_hAT PF05699.14 GBG72295.1 - 7.3e-05 22.5 0.2 0.00015 21.4 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Phage_integrase PF00589.22 GBG72296.1 - 2.2e-07 30.8 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Exostosin PF03016.15 GBG72298.1 - 3.7e-60 203.7 0.0 5.1e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Exostosin family DDE_Tnp_4 PF13359.6 GBG72299.1 - 1.6e-18 66.9 0.0 2.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72299.1 - 4.1e-11 42.9 0.0 7.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Ribosomal_60s PF00428.19 GBG72299.1 - 0.0025 18.4 15.1 0.0055 17.3 15.1 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pentapeptide_4 PF13599.6 GBG72299.1 - 0.01 16.0 0.6 0.061 13.5 0.6 2.2 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) NOA36 PF06524.12 GBG72299.1 - 1.1 8.5 3.3 7.5 5.8 2.9 2.0 2 0 0 2 2 2 0 NOA36 protein Chisel PF15355.6 GBG72300.1 - 0.18 12.1 0.6 0.43 10.9 0.6 1.6 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel Nop14 PF04147.12 GBG72302.1 - 0.1 10.8 39.6 0.16 10.1 39.6 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG72302.1 - 0.9 7.7 32.3 1.7 6.8 32.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG72302.1 - 1.7 7.3 14.6 3 6.5 14.6 1.3 1 0 0 1 1 1 0 Presenilin Mpp10 PF04006.12 GBG72302.1 - 2.3 6.6 35.8 3.6 5.9 35.8 1.2 1 0 0 1 1 1 0 Mpp10 protein SMN PF06003.12 GBG72302.1 - 2.8 7.1 11.2 5.1 6.3 11.2 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Lin-8 PF03353.15 GBG72302.1 - 3.5 7.1 17.5 5.1 6.6 17.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 GBG72302.1 - 5.9 5.7 17.0 9.7 5.0 17.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Apt1 PF10351.9 GBG72302.1 - 6 5.6 9.6 8.5 5.1 9.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-CCHC PF00098.23 GBG72303.1 - 6.1e-07 29.2 1.8 1.1e-06 28.5 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG72303.1 - 0.033 13.9 1.1 0.067 12.9 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG72303.1 - 0.079 12.8 0.4 0.19 11.6 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Packaging_FI PF14000.6 GBG72303.1 - 1.7 9.1 9.2 0.43 11.0 0.2 3.0 2 1 1 3 3 3 0 DNA packaging protein FI Methyltrn_RNA_4 PF09936.9 GBG72303.1 - 5.7 6.8 9.1 0.084 12.7 0.8 2.1 2 1 0 2 2 2 0 SAM-dependent RNA methyltransferase Exostosin PF03016.15 GBG72304.1 - 3.3e-59 200.6 0.0 4.7e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Exostosin family zf-CCHC PF00098.23 GBG72305.1 - 1.8e-05 24.6 2.6 3.1e-05 23.8 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG72305.1 - 0.0045 16.8 3.3 0.0058 16.4 0.9 2.0 2 0 0 2 2 2 1 Zinc knuckle CDC45 PF02724.14 GBG72305.1 - 0.85 7.8 9.2 1 7.5 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC_3 PF13917.6 GBG72305.1 - 1.3 9.1 8.1 0.069 13.1 2.0 2.1 2 0 0 2 2 2 0 Zinc knuckle Presenilin PF01080.17 GBG72305.1 - 5 5.8 8.8 5.4 5.7 8.8 1.3 1 0 0 1 1 1 0 Presenilin DUF4065 PF13274.6 GBG72305.1 - 7.5 7.5 8.9 2.9e+02 2.4 8.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) ALMT PF11744.8 GBG72305.1 - 7.6 5.2 6.1 11 4.7 6.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 GBG72305.1 - 7.9 4.5 7.4 8 4.5 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endostatin PF06482.11 GBG72305.1 - 9.5 5.6 9.9 7.1 6.0 8.3 1.4 1 1 0 1 1 1 0 Collagenase NC10 and Endostatin Lsr2 PF11774.8 GBG72306.1 - 4 7.6 6.1 42 4.3 0.1 2.5 2 0 0 2 2 2 0 Lsr2 RT_RNaseH_2 PF17919.1 GBG72307.1 - 8.5e-31 106.0 0.0 2.1e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72307.1 - 8.7e-29 99.9 1.1 1.4e-28 99.2 0.0 2.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase MRPL52 PF18699.1 GBG72307.1 - 0.11 12.7 0.2 0.11 12.7 0.2 4.0 3 1 2 5 5 5 0 Mitoribosomal protein mL52 FTHFS PF01268.19 GBG72307.1 - 0.3 9.2 1.5 0.42 8.7 1.5 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase TadF PF16964.5 GBG72307.1 - 0.62 9.8 4.4 1.4 8.7 4.4 1.5 1 0 0 1 1 1 0 Putative tight adherence pilin protein F BUD22 PF09073.10 GBG72307.1 - 2.2 7.5 43.7 0.11 11.9 12.8 2.3 2 0 0 2 2 2 0 BUD22 RT_RNaseH PF17917.1 GBG72308.1 - 1.5e-28 99.1 0.1 4.1e-28 97.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72308.1 - 2.2e-28 98.2 0.0 5.1e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72308.1 - 2.3e-19 69.3 1.0 4.7e-19 68.2 1.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72308.1 - 0.034 14.3 0.1 0.22 11.7 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 GBG72308.1 - 0.038 14.2 0.2 0.11 12.8 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG72309.1 - 2.5e-26 92.6 0.1 6.8e-26 91.2 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72309.1 - 2.6e-19 69.1 0.1 1.6e-18 66.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72309.1 - 1.9e-18 66.7 0.0 3.8e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG72309.1 - 0.0057 16.4 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG72309.1 - 0.016 15.5 0.0 0.045 14.0 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4187 PF13821.6 GBG72309.1 - 0.052 13.3 0.5 0.14 11.9 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RVT_1 PF00078.27 GBG72310.1 - 3.2e-52 177.3 0.7 2.4e-25 89.4 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72310.1 - 6.3e-27 93.6 0.0 8.2e-19 67.5 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72310.1 - 8.9e-14 51.7 0.3 5.3e-11 42.7 0.0 3.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG72310.1 - 3.3e-07 30.8 0.0 9.3e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72310.1 - 1e-06 29.3 0.0 3.1e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG72310.1 - 2.5e-05 24.1 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72310.1 - 2.7e-05 23.9 0.0 6.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG72310.1 - 0.0046 17.2 0.3 0.022 15.0 0.3 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG72310.1 - 0.049 13.4 0.8 0.2 11.5 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) CLZ PF16526.5 GBG72310.1 - 1.5 9.2 7.7 0.22 11.9 0.4 3.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RVT_1 PF00078.27 GBG72311.1 - 4.3e-37 127.8 0.0 7.7e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72311.1 - 1.2e-29 102.3 0.0 3.4e-29 100.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72311.1 - 9.8e-29 99.7 0.1 2.3e-28 98.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72311.1 - 3e-19 68.8 0.3 7.8e-19 67.5 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72311.1 - 8e-13 48.6 0.0 2e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG72311.1 - 0.002 17.9 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG72311.1 - 0.0026 17.9 0.0 0.0087 16.3 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger gpUL132 PF11359.8 GBG72311.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 FAM60A PF15396.6 GBG72311.1 - 0.055 13.5 5.2 0.12 12.4 5.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A 2OG-FeII_Oxy_2 PF13532.6 GBG72311.1 - 0.088 13.0 0.4 0.26 11.4 0.4 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RVT_1 PF00078.27 GBG72312.1 - 5.1e-24 85.0 0.1 1.6e-22 80.1 0.1 2.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72312.1 - 3.5e-12 46.2 0.0 9.8e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72312.1 - 0.005 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCCH PF00642.24 GBG72313.1 - 6.2e-05 22.8 2.0 0.00012 21.9 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Syntaxin_2 PF14523.6 GBG72313.1 - 0.012 16.0 1.0 0.024 15.0 1.0 1.5 1 0 0 1 1 1 0 Syntaxin-like protein Tropomyosin_1 PF12718.7 GBG72313.1 - 0.021 15.0 13.4 0.036 14.2 13.4 1.4 1 0 0 1 1 1 0 Tropomyosin like HOOK PF05622.12 GBG72313.1 - 0.11 10.6 12.4 0.15 10.2 12.4 1.1 1 0 0 1 1 1 0 HOOK protein zf-CCCH_3 PF15663.5 GBG72313.1 - 0.12 12.6 0.1 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger containing family FUSC PF04632.12 GBG72313.1 - 0.12 10.9 2.7 0.18 10.3 2.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 GBG72313.1 - 0.17 12.1 12.6 0.39 10.9 12.6 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Heme_oxygenase PF01126.20 GBG72313.1 - 0.2 11.4 3.0 6.5 6.5 0.1 2.2 1 1 1 2 2 2 0 Heme oxygenase CorA PF01544.18 GBG72313.1 - 0.29 10.4 1.1 0.4 10.0 1.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf_CCCH_4 PF18345.1 GBG72313.1 - 0.65 10.1 3.2 5.8 7.1 3.2 2.3 1 1 0 1 1 1 0 Zinc finger domain Mod_r PF07200.13 GBG72313.1 - 0.92 9.6 12.4 1.4 9.0 12.4 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein OmpH PF03938.14 GBG72313.1 - 1.3 9.4 11.4 2.2 8.6 11.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BRE1 PF08647.11 GBG72313.1 - 1.3 9.2 14.8 1.8 8.7 5.3 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase zf-C4H2 PF10146.9 GBG72313.1 - 3.9 7.7 10.3 0.097 13.0 3.4 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein SKA2 PF16740.5 GBG72313.1 - 4.4 7.1 12.9 0.74 9.6 3.0 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 APG6_N PF17675.1 GBG72313.1 - 6.6 7.3 15.0 6.6 7.3 12.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region RVT_1 PF00078.27 GBG72315.1 - 2.4e-24 86.1 0.0 4.1e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PDDEXK_1 PF12705.7 GBG72315.1 - 2.2 8.1 6.1 15 5.4 0.2 2.6 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily DUF4407 PF14362.6 GBG72315.1 - 2.6 7.3 6.0 38 3.5 8.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) eIF3_subunit PF08597.10 GBG72315.1 - 4.7 7.0 19.5 8.4 6.2 19.5 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit peroxidase PF00141.23 GBG72316.1 - 4.5e-47 160.7 0.0 7e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Autophagy_N PF03986.13 GBG72317.1 - 0.0096 15.9 3.2 0.019 14.9 3.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain NYAP_C PF15452.6 GBG72317.1 - 0.13 12.1 5.2 0.13 12.0 4.2 1.5 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter RNA_pol_Rpc4 PF05132.14 GBG72317.1 - 0.42 11.0 4.6 0.64 10.4 4.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 GBG72317.1 - 0.49 10.2 10.0 0.75 9.6 10.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2457 PF10446.9 GBG72317.1 - 0.87 8.7 23.4 1.2 8.2 23.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.12 GBG72317.1 - 9 5.6 25.8 16 4.8 25.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1517 PF07466.11 GBG72319.1 - 4.4e-68 229.1 0.0 5.9e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) TPM_phosphatase PF04536.14 GBG72320.1 - 6.5e-08 32.8 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 TPM domain Response_reg PF00072.24 GBG72321.1 - 5.2e-21 74.9 0.0 1.2e-20 73.8 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GBG72321.1 - 1.6e-18 67.3 0.0 8.7e-18 64.9 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GBG72321.1 - 4.6e-08 33.0 0.5 1.3e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 GBG72321.1 - 0.013 16.1 0.0 0.083 13.5 0.0 2.4 2 1 0 2 2 2 0 GAF domain RVT_1 PF00078.27 GBG72322.1 - 2.4e-30 105.7 0.1 4e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72322.1 - 6.5e-30 103.1 0.0 6.4e-15 55.0 0.0 2.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72322.1 - 1.2e-28 99.4 0.0 2.9e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72322.1 - 5.3e-17 61.7 0.0 2.5e-16 59.5 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG72322.1 - 5.8e-10 39.4 0.0 2e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72322.1 - 1.5e-05 25.1 0.0 7.2e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 GBG72323.1 - 2.1e-22 79.7 0.6 1.2e-11 44.6 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72323.1 - 2.3e-22 78.9 0.0 6.4e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72323.1 - 4.7e-11 42.9 0.0 1.4e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ADP_ribosyl_GH PF03747.14 GBG72323.1 - 0.0011 18.8 0.4 0.022 14.5 0.9 2.4 2 0 0 2 2 2 1 ADP-ribosylglycohydrolase Retrotrans_gag PF03732.17 GBG72323.1 - 0.021 15.1 0.3 0.21 11.9 0.0 2.9 4 0 0 4 4 4 0 Retrotransposon gag protein DUF2052 PF09747.9 GBG72323.1 - 0.2 11.8 13.2 0.38 10.8 13.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) eIF3_subunit PF08597.10 GBG72323.1 - 2.5 7.9 24.3 4.8 7.0 24.3 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PKcGMP_CC PF16808.5 GBG72324.1 - 0.047 13.5 11.1 0.26 11.2 0.9 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1481 PF07356.12 GBG72324.1 - 0.17 11.6 0.5 0.29 10.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) TMF_DNA_bd PF12329.8 GBG72324.1 - 0.27 11.3 11.8 13 5.9 11.5 2.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Potassium_chann PF11404.8 GBG72324.1 - 1.7 8.5 4.5 1.1 9.1 1.6 2.3 2 0 0 2 2 2 0 Potassium voltage-gated channel LETM1 PF07766.13 GBG72324.1 - 2.4 7.4 6.3 2 7.7 0.1 2.2 2 0 0 2 2 2 0 LETM1-like protein DUF883 PF05957.13 GBG72324.1 - 5.6 7.6 5.8 16 6.2 5.8 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RVT_1 PF00078.27 GBG72325.1 - 1.8e-30 106.1 0.4 2.8e-30 105.5 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72325.1 - 1e-27 96.0 0.0 3.9e-27 94.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72325.1 - 1.2e-24 86.6 0.0 3.4e-24 85.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG72325.1 - 1.2e-05 25.8 0.0 2.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72325.1 - 2.4e-05 24.8 0.0 6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG72325.1 - 0.00023 20.9 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG72325.1 - 0.00024 21.3 0.5 0.0011 19.2 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein LMBR1 PF04791.16 GBG72326.1 - 1.2 8.0 5.1 2.3 7.0 5.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 GBG72326.1 - 8.5 4.2 6.8 15 3.4 6.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RT_RNaseH_2 PF17919.1 GBG72327.1 - 3.1e-26 91.3 0.0 5.6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72327.1 - 7.1e-22 77.7 0.0 1.3e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72327.1 - 1.9e-05 24.3 0.1 2.9e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CobT PF06213.12 GBG72327.1 - 0.7 9.2 8.6 1 8.7 8.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RVT_1 PF00078.27 GBG72328.1 - 2.1e-28 99.3 0.1 3.1e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72328.1 - 4.7e-14 52.2 0.0 9.9e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG72328.1 - 3.6e-12 46.0 0.0 8.6e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG72328.1 - 0.071 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase YL1 PF05764.13 GBG72329.1 - 0.0019 18.4 1.1 0.0031 17.7 1.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Presenilin PF01080.17 GBG72329.1 - 0.034 12.9 0.4 0.047 12.4 0.4 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG72329.1 - 0.34 9.1 1.4 0.45 8.7 1.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG72329.1 - 0.39 9.0 2.4 0.53 8.5 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 GBG72329.1 - 0.8 9.5 2.7 1.4 8.7 2.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 GBG72329.1 - 6.9 7.1 8.0 15 6.0 8.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain gag-asp_proteas PF13975.6 GBG72332.1 - 1e-05 26.0 0.3 3.6e-05 24.2 0.0 2.1 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72332.1 - 0.012 16.3 0.0 0.15 12.7 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 GBG72332.1 - 0.13 12.6 0.0 0.44 10.9 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72332.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease TbpB_A PF17484.2 GBG72332.1 - 0.72 10.6 4.0 1.6 9.5 4.0 1.5 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B TP53IP5 PF15331.6 GBG72332.1 - 1.5 9.0 8.4 2.7 8.1 8.4 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PIP5K PF01504.18 GBG72333.1 - 1.3e-85 287.0 0.0 9.5e-85 284.1 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MORN PF02493.20 GBG72333.1 - 5.3e-43 142.4 54.9 2.1e-07 30.4 0.4 9.4 9 0 0 9 9 9 8 MORN repeat PPR_2 PF13041.6 GBG72334.1 - 4.5e-76 250.9 9.9 6.5e-14 51.9 0.3 12.4 9 3 4 13 13 13 10 PPR repeat family PPR_3 PF13812.6 GBG72334.1 - 1.7e-63 210.6 5.2 1.2e-11 44.5 0.2 10.9 7 3 4 11 11 11 10 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG72334.1 - 3e-48 161.2 17.7 2e-07 30.6 0.0 14.4 14 0 0 14 14 14 7 PPR repeat PPR PF01535.20 GBG72334.1 - 6e-45 148.4 20.5 1.3e-05 25.1 0.0 14.9 15 0 0 15 15 15 7 PPR repeat PPR_long PF17177.4 GBG72334.1 - 1.2e-31 109.8 0.2 2.2e-11 43.6 0.0 5.2 3 1 1 5 5 5 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG72334.1 - 9.2e-06 26.1 4.3 0.028 14.9 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat ATP13 PF12921.7 GBG72334.1 - 0.00036 20.4 0.0 17 5.3 0.0 5.0 4 1 0 4 4 4 1 Mitochondrial ATPase expression Exog_C PF18026.1 GBG72334.1 - 0.01 15.9 3.3 29 4.8 0.0 5.9 8 0 0 8 8 8 0 Endo/exonuclease (EXOG) C-terminal domain ECSIT PF06239.11 GBG72334.1 - 0.024 13.8 0.0 9.3 5.3 0.0 3.7 3 1 2 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_16 PF13432.6 GBG72334.1 - 0.099 13.3 5.8 1.2 9.8 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_2 PF13041.6 GBG72335.1 - 4.7e-76 250.8 9.8 6.5e-14 51.9 0.3 12.4 9 3 4 13 13 13 10 PPR repeat family PPR_3 PF13812.6 GBG72335.1 - 1.2e-61 204.7 4.8 1.2e-11 44.5 0.2 10.9 7 3 4 11 11 11 10 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG72335.1 - 3e-48 161.2 17.7 2e-07 30.6 0.0 14.4 14 0 0 14 14 14 7 PPR repeat PPR PF01535.20 GBG72335.1 - 2.3e-44 146.6 20.6 1.3e-05 25.1 0.0 14.4 14 0 0 14 14 14 7 PPR repeat PPR_long PF17177.4 GBG72335.1 - 1.2e-30 106.4 0.2 3.8e-10 39.5 0.0 5.5 3 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG72335.1 - 9.2e-06 26.1 4.3 0.028 14.9 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat ATP13 PF12921.7 GBG72335.1 - 0.00063 19.6 0.0 17 5.3 0.0 4.6 3 1 0 3 3 3 1 Mitochondrial ATPase expression Exog_C PF18026.1 GBG72335.1 - 0.011 15.7 3.7 29 4.8 0.0 6.0 9 0 0 9 9 9 0 Endo/exonuclease (EXOG) C-terminal domain ECSIT PF06239.11 GBG72335.1 - 0.027 13.6 0.0 9.2 5.3 0.0 3.6 3 1 1 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_16 PF13432.6 GBG72335.1 - 0.1 13.3 5.8 1.2 9.8 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.11 GBG72336.1 - 9.7 7.0 14.8 11 6.8 14.8 1.1 1 0 0 1 1 1 0 U3 snoRNA associated Kri1 PF05178.12 GBG72337.1 - 6.6 7.4 25.2 6.3 7.4 14.2 2.8 2 0 0 2 2 2 0 KRI1-like family RT_RNaseH_2 PF17919.1 GBG72338.1 - 7.8e-30 102.9 0.0 2.4e-29 101.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72338.1 - 5.2e-18 65.3 0.2 1.6e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72338.1 - 3.1e-13 50.0 0.0 1.1e-12 48.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG72338.1 - 3.7e-11 43.0 0.0 7.6e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG72338.1 - 0.044 13.6 0.8 3.2 7.6 0.0 2.8 2 0 0 2 2 2 0 Integrase core domain Chromo PF00385.24 GBG72338.1 - 0.09 12.7 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG72339.1 - 0.0033 17.7 0.5 0.0033 17.7 0.5 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG72340.1 - 1.1e-05 25.9 0.0 3.6e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG72340.1 - 3.9e-05 23.8 7.1 0.058 13.7 0.0 4.9 5 0 0 5 5 5 3 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG72340.1 - 6.1e-05 23.6 0.0 0.00028 21.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG72340.1 - 8.2e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72340.1 - 0.088 12.6 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease SlyX PF04102.12 GBG72341.1 - 0.0016 19.0 3.1 0.0016 19.0 3.1 3.6 2 2 1 3 3 3 1 SlyX CorA PF01544.18 GBG72341.1 - 0.36 10.1 4.1 0.34 10.2 0.2 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein SYCE1 PF15233.6 GBG72341.1 - 0.72 9.9 10.4 0.11 12.5 1.4 2.4 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 RVT_1 PF00078.27 GBG72342.1 - 1.7e-36 125.8 0.1 2.8e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72342.1 - 6.4e-29 99.9 0.0 1.5e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72342.1 - 1.9e-28 98.8 0.1 4.1e-28 97.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72342.1 - 6e-17 61.5 0.3 1.9e-16 59.9 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG72342.1 - 0.0036 17.5 0.1 0.0092 16.2 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG72342.1 - 0.017 15.4 1.8 1.2 9.4 0.0 3.7 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG72343.1 - 1.6e-21 76.2 0.1 4.4e-20 71.6 0.0 3.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72343.1 - 4.1e-13 49.5 0.0 1.3e-11 44.7 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72343.1 - 0.00022 21.4 0.0 0.00077 19.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG72343.1 - 0.031 13.8 0.7 0.11 12.0 0.1 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) LAP1C PF05609.12 GBG72343.1 - 4.9 6.1 20.7 7.8 5.5 20.7 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RT_RNaseH_2 PF17919.1 GBG72345.1 - 2.7e-17 62.6 0.0 7.2e-17 61.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72345.1 - 2.4e-13 50.1 0.0 4.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72345.1 - 3.1e-06 27.4 0.0 8.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG72345.1 - 0.011 15.7 4.9 0.021 14.8 1.8 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG72345.1 - 0.16 12.1 13.4 0.087 12.9 2.4 2.5 2 0 0 2 2 2 0 Zinc knuckle DXP_reductoisom PF02670.16 GBG72346.1 - 1.5e-45 155.0 5.3 2.5e-45 154.3 0.7 2.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.12 GBG72346.1 - 2.5e-40 136.5 0.3 8.5e-40 134.8 0.0 2.1 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXPR_C PF13288.6 GBG72346.1 - 1.6e-36 125.1 0.0 3.4e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain Semialdhyde_dh PF01118.24 GBG72346.1 - 0.08 13.4 0.1 0.42 11.1 0.0 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 GBG72346.1 - 0.084 13.5 0.3 1.7 9.3 0.1 3.0 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Dimer_Tnp_hAT PF05699.14 GBG72347.1 - 0.00016 21.4 0.5 0.00032 20.4 0.5 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AAA_34 PF13872.6 GBG72348.1 - 8.6e-134 445.2 0.0 1.4e-133 444.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 GBG72348.1 - 2.7e-105 351.9 0.0 4.8e-105 351.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue RT_RNaseH_2 PF17919.1 GBG72348.1 - 1.4e-31 108.5 0.2 3.3e-31 107.3 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72348.1 - 3.2e-27 94.9 0.3 7.4e-27 93.7 0.3 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72348.1 - 3.2e-18 65.6 0.1 9.5e-18 64.1 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72348.1 - 8.7e-14 51.7 0.0 2.1e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PHD PF00628.29 GBG72348.1 - 4.4e-07 29.7 13.4 4.4e-07 29.7 13.4 4.3 5 1 0 5 5 5 1 PHD-finger ResIII PF04851.15 GBG72348.1 - 4.9e-05 23.4 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RVT_1 PF00078.27 GBG72348.1 - 0.03 13.9 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Zot PF05707.12 GBG72348.1 - 0.08 12.6 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) zf-Sec23_Sec24 PF04810.15 GBG72348.1 - 0.47 10.5 4.5 1.5 8.9 0.4 3.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Tub_N PF16322.5 GBG72348.1 - 0.85 10.0 7.8 1.4 9.3 2.7 2.3 2 0 0 2 2 2 0 Tubby N-terminal AAA_34 PF13872.6 GBG72349.1 - 8.5e-134 445.2 0.0 1.4e-133 444.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 GBG72349.1 - 2.7e-105 351.9 0.0 4.8e-105 351.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue RT_RNaseH_2 PF17919.1 GBG72349.1 - 1.4e-31 108.5 0.2 3.3e-31 107.3 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72349.1 - 3.2e-27 94.9 0.3 7.3e-27 93.7 0.3 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72349.1 - 3.2e-18 65.6 0.1 9.4e-18 64.1 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72349.1 - 8.7e-14 51.7 0.0 2.1e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PHD PF00628.29 GBG72349.1 - 4.4e-07 29.7 13.4 4.4e-07 29.7 13.4 4.3 5 1 0 5 5 5 1 PHD-finger ResIII PF04851.15 GBG72349.1 - 4.8e-05 23.4 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RVT_1 PF00078.27 GBG72349.1 - 0.029 13.9 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Zot PF05707.12 GBG72349.1 - 0.08 12.6 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) zf-Sec23_Sec24 PF04810.15 GBG72349.1 - 0.47 10.5 4.5 1.5 8.9 0.4 3.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Tub_N PF16322.5 GBG72349.1 - 0.96 9.8 6.5 2 8.8 1.7 2.3 2 0 0 2 2 2 0 Tubby N-terminal gag-asp_proteas PF13975.6 GBG72350.1 - 4.6e-07 30.3 0.0 1.1e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72350.1 - 6.6e-07 29.9 0.0 1.3e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG72350.1 - 2e-05 24.4 0.0 4.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG72350.1 - 0.00021 21.5 0.0 0.00079 19.7 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG72350.1 - 0.00045 20.0 0.0 0.00075 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease V_ATPase_I PF01496.19 GBG72351.1 - 0.00078 17.5 0.0 0.00088 17.3 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 GBG72351.1 - 0.01 14.3 0.1 0.011 14.2 0.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RSN1_TM PF13967.6 GBG72351.1 - 0.015 15.0 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport SpoIIIAH PF12685.7 GBG72351.1 - 0.026 14.4 11.1 0.031 14.1 11.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.22 GBG72351.1 - 0.06 12.6 0.1 0.063 12.5 0.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter EMP70 PF02990.16 GBG72351.1 - 0.1 11.3 0.1 0.1 11.3 0.1 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 DUF2615 PF11027.8 GBG72351.1 - 0.47 10.6 11.4 3.7 7.7 11.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) SDA1 PF05285.12 GBG72351.1 - 1.2 8.5 51.1 1.2 8.5 51.1 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 GBG72351.1 - 6.4 5.7 7.0 8.7 5.2 7.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Myb_DNA-bind_4 PF13837.6 GBG72354.1 - 3.1e-08 33.9 1.1 5.4e-08 33.1 1.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG72354.1 - 2.3e-05 24.5 0.3 0.00012 22.2 0.3 2.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG72354.1 - 0.00062 19.8 0.5 0.0014 18.7 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG72354.1 - 0.024 14.9 1.5 0.042 14.1 0.0 2.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72354.1 - 0.045 14.1 1.2 0.11 12.9 1.2 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Cnn_1N PF07989.11 GBG72356.1 - 0.0096 16.1 3.4 0.0096 16.1 3.4 9.3 3 3 5 8 8 8 2 Centrosomin N-terminal motif 1 Gcd10p PF04189.13 GBG72357.1 - 0.21 10.7 7.2 0.37 9.8 7.2 1.5 1 1 0 1 1 1 0 Gcd10p family MDM10 PF12519.8 GBG72357.1 - 5 5.9 6.5 6.7 5.5 6.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4611 PF15387.6 GBG72359.1 - 2.4 8.5 12.8 0.027 14.7 3.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2262 PF10020.9 GBG72359.1 - 3.5 8.0 10.3 7.8 6.9 10.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) SURF2 PF05477.11 GBG72359.1 - 7 6.3 14.1 13 5.4 14.1 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RVT_1 PF00078.27 GBG72360.1 - 7.4e-31 107.4 0.1 1.1e-30 106.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72360.1 - 2.4e-27 94.9 0.0 5.5e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72360.1 - 7.8e-15 55.1 0.0 1.6e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72361.1 - 2.3e-35 122.1 0.2 3.4e-35 121.6 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72361.1 - 8.7e-16 57.8 0.0 3.1e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72361.1 - 3.7e-07 30.4 0.0 8.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4392 PF14336.6 GBG72361.1 - 0.059 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) GATase_4 PF13230.6 GBG72361.1 - 0.081 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II RT_RNaseH PF17917.1 GBG72362.1 - 4.8e-15 55.7 0.3 1.8e-14 53.9 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72362.1 - 1.5e-09 37.7 0.2 4.2e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72362.1 - 6.3e-08 32.6 0.0 1.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG72362.1 - 9.8e-08 31.9 0.0 2.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72362.1 - 1.3e-07 32.1 0.0 6.1e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72362.1 - 1.5e-05 25.5 0.1 0.0001 22.8 0.0 2.5 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG72362.1 - 0.0048 17.1 0.0 0.0048 17.1 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG72362.1 - 0.03 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease IL28A PF15177.6 GBG72362.1 - 0.21 11.4 4.8 0.45 10.3 4.8 1.5 1 0 0 1 1 1 0 Interleukin-28A SlyX PF04102.12 GBG72362.1 - 7.1 7.3 7.3 0.78 10.4 0.9 2.8 3 0 0 3 3 3 0 SlyX RT_RNaseH_2 PF17919.1 GBG72363.1 - 1.3e-33 115.0 0.1 3.1e-33 113.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72363.1 - 2.6e-32 112.1 0.1 5e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72363.1 - 6.3e-27 93.9 0.0 1.8e-26 92.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72363.1 - 1e-18 67.2 0.1 2.3e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72363.1 - 1.9e-14 53.8 0.1 1e-13 51.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG72363.1 - 0.0067 16.6 0.0 0.035 14.3 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger DUF3863 PF12979.7 GBG72363.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) RT_RNaseH_2 PF17919.1 GBG72364.1 - 6.5e-54 180.1 0.0 4.7e-29 100.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72364.1 - 3.6e-53 178.3 1.1 7.5e-28 96.9 0.2 3.4 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72364.1 - 1.9e-21 76.6 0.1 1.7e-12 47.4 0.2 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72364.1 - 6.2e-18 64.7 0.3 2e-17 63.0 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72364.1 - 4.1e-13 49.6 0.4 9.7e-09 35.5 0.1 2.7 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG72365.1 - 3e-18 65.7 0.0 8.4e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72365.1 - 5.1e-16 58.9 0.1 2.5e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72365.1 - 3e-10 40.0 0.0 5.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2066 PF09839.9 GBG72365.1 - 0.093 12.1 1.6 0.16 11.3 1.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) rve PF00665.26 GBG72366.1 - 1.7e-08 34.7 0.0 4.3e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PEX-2N PF09263.10 GBG72366.1 - 0.083 13.2 0.6 0.2 12.0 0.6 1.7 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal Nexin_C PF08628.12 GBG72366.1 - 0.91 10.1 3.9 0.94 10.1 0.6 2.4 2 0 0 2 2 2 0 Sorting nexin C terminal DUF4085 PF13315.6 GBG72366.1 - 1.1 8.8 5.8 8.4 6.0 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Adaptin_binding PF10199.9 GBG72366.1 - 3.6 8.2 13.3 0.77 10.4 6.0 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RVT_1 PF00078.27 GBG72367.1 - 1.2e-32 113.2 0.0 2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72367.1 - 4e-17 62.1 0.0 1.4e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72367.1 - 1.7e-09 37.9 0.2 7.4e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG72367.1 - 6.1e-07 29.3 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72367.1 - 0.0013 19.3 0.0 0.003 18.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG72367.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) TerB_C PF15615.6 GBG72367.1 - 0.029 14.7 5.0 0.058 13.7 5.0 1.5 1 0 0 1 1 1 0 TerB-C domain DUF1764 PF08576.10 GBG72367.1 - 0.59 11.1 10.2 1.7 9.6 10.0 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Presenilin PF01080.17 GBG72367.1 - 1.5 7.5 3.5 2.2 7.0 3.5 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG72367.1 - 3.4 5.8 6.9 5 5.3 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Mrr_N PF14338.6 GBG72367.1 - 3.5 7.8 7.6 54 4.0 3.8 3.3 3 0 0 3 3 3 0 Mrr N-terminal domain DUF5401 PF17380.2 GBG72367.1 - 4.6 5.2 21.8 6.8 4.6 21.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RT_RNaseH_2 PF17919.1 GBG72368.1 - 6.5e-29 99.9 0.0 1.6e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72368.1 - 1.8e-15 57.1 0.0 4.2e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72368.1 - 1.2e-09 38.0 0.2 2.1e-09 37.3 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-B_dimeris PF09026.10 GBG72368.1 - 8.6e-05 22.9 12.6 0.00016 22.0 11.3 2.1 2 0 0 2 2 2 1 Centromere protein B dimerisation domain GCIP PF13324.6 GBG72368.1 - 0.0042 16.7 11.6 0.0091 15.6 11.6 1.5 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting TFIIA PF03153.13 GBG72368.1 - 0.062 13.3 18.2 0.096 12.7 18.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRN3 PF05327.11 GBG72368.1 - 0.12 10.9 6.8 0.15 10.5 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4611 PF15387.6 GBG72368.1 - 0.18 12.0 12.1 0.056 13.7 8.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 GBG72368.1 - 0.18 11.1 13.0 0.34 10.2 13.0 1.4 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 GBG72368.1 - 1.8 8.1 10.6 2.6 7.6 10.6 1.2 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 GBG72368.1 - 1.9 6.5 13.4 3.3 5.7 13.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi FtsK_SpoIIIE PF01580.18 GBG72369.1 - 0.64 9.3 5.2 0.56 9.5 3.7 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family Met_gamma_lyase PF06838.11 GBG72370.1 - 0.025 13.1 0.0 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase PH_2 PF08458.10 GBG72370.1 - 0.033 14.5 1.3 0.23 11.8 0.3 2.9 2 1 0 2 2 2 0 Plant pleckstrin homology-like region DUF4159 PF13709.6 GBG72370.1 - 0.044 13.2 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Ish1 PF10281.9 GBG72370.1 - 0.051 13.9 0.8 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Ribosomal_S7e PF01251.18 GBG72371.1 - 1.6e-82 275.7 2.3 1.8e-82 275.6 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e WcbI PF18588.1 GBG72371.1 - 0.15 11.7 0.4 0.61 9.7 0.1 1.8 1 1 1 2 2 2 0 Polysaccharide biosynthesis enzyme WcbI NUP50 PF08911.11 GBG72371.1 - 3.4 8.4 4.8 29 5.4 0.1 2.3 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Histone PF00125.24 GBG72372.1 - 5.6e-19 68.8 0.1 5.6e-19 68.8 0.1 3.4 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG72372.1 - 0.12 12.8 0.3 0.27 11.6 0.3 1.5 1 0 0 1 1 1 0 CENP-S protein DUF659 PF04937.15 GBG72373.1 - 3.5e-11 43.2 0.0 7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF1660 PF07874.11 GBG72373.1 - 0.62 10.6 3.8 1.8 9.1 3.8 1.8 1 0 0 1 1 1 0 Prophage protein (DUF1660) SHMT PF00464.19 GBG72374.1 - 7.9e-191 633.9 0.0 9.3e-191 633.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Exo_endo_phos PF03372.23 GBG72375.1 - 0.18 11.3 0.2 0.31 10.5 0.2 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Trypan_PARP PF05887.11 GBG72377.1 - 8.9 6.3 9.5 0.32 11.0 0.2 2.7 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) RT_RNaseH_2 PF17919.1 GBG72378.1 - 1.8e-23 82.4 0.0 5.8e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72378.1 - 5.3e-22 78.1 0.0 1.3e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72378.1 - 1.2e-21 77.3 0.0 2.5e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG72378.1 - 7.2e-05 23.4 0.0 0.00015 22.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72378.1 - 8.5e-05 23.0 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG72378.1 - 0.00031 20.8 0.1 0.00031 20.8 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG72378.1 - 0.0004 20.2 0.0 0.00084 19.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG72378.1 - 0.0006 19.6 0.0 0.0017 18.1 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Longin PF13774.6 GBG72378.1 - 0.3 11.1 1.2 9.7 6.3 0.2 3.2 3 0 0 3 3 3 0 Regulated-SNARE-like domain MIT PF04212.18 GBG72379.1 - 0.16 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DASH_Dad3 PF08656.10 GBG72380.1 - 0.19 11.8 2.0 0.37 10.9 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 MADF_DNA_bdg PF10545.9 GBG72380.1 - 0.89 9.9 7.3 6.3 7.2 0.4 2.7 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PSGP PF07276.11 GBG72380.1 - 5 7.7 5.2 20 5.8 0.1 2.9 2 0 0 2 2 2 0 Apopolysialoglycoprotein (PSGP) Retrotrans_gag PF03732.17 GBG72381.1 - 0.049 13.9 0.2 0.23 11.8 0.1 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG72382.1 - 4.8e-24 84.3 0.0 7.5e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72382.1 - 1.3e-22 80.1 0.0 2.8e-22 79.0 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Exo_endo_phos PF03372.23 GBG72383.1 - 4.8e-06 26.2 0.0 8.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG72383.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TolA_bind_tri PF16331.5 GBG72384.1 - 0.0049 16.9 3.4 0.0049 16.9 3.4 2.9 3 1 0 3 3 3 1 TolA binding protein trimerisation ATG16 PF08614.11 GBG72384.1 - 0.016 15.5 14.4 0.058 13.6 2.1 3.9 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 GBG72384.1 - 0.2 12.3 14.6 0.84 10.3 2.9 4.5 3 1 1 4 4 4 0 SlyX Matrilin_ccoil PF10393.9 GBG72384.1 - 0.49 10.3 4.5 1.4 8.8 0.2 3.0 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1664 PF07889.12 GBG72384.1 - 1.2 9.2 10.8 0.43 10.6 1.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 GBG72384.1 - 4.1 5.9 8.0 2.3 6.7 0.5 2.4 2 0 0 2 2 2 0 AAA domain SesA PF17107.5 GBG72384.1 - 5.5 7.2 10.3 5.7 7.2 1.4 3.4 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Filament PF00038.21 GBG72384.1 - 6 6.4 9.6 6.3 6.3 1.8 2.4 2 0 0 2 2 2 0 Intermediate filament protein RT_RNaseH_2 PF17919.1 GBG72385.1 - 1.2e-26 92.7 0.0 2.8e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72385.1 - 1.2e-24 86.6 0.0 3.6e-24 85.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72385.1 - 0.0063 16.0 0.0 0.041 13.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) VIT1 PF01988.19 GBG72385.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.4 3 0 0 3 3 3 0 VIT family RT_RNaseH_2 PF17919.1 GBG72387.1 - 1e-27 96.1 0.0 2.7e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72387.1 - 2.8e-27 95.1 0.1 6.8e-27 93.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG72387.1 - 5.6e-07 29.4 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72387.1 - 5.1e-05 23.8 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72387.1 - 0.00034 21.1 0.0 0.00097 19.7 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG72387.1 - 0.0017 18.1 0.0 0.005 16.6 0.0 1.8 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG72387.1 - 0.061 12.9 1.0 0.1 12.2 0.1 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_lysozyme PF00959.19 GBG72387.1 - 0.13 12.8 0.4 1.2 9.6 0.1 2.7 2 1 0 2 2 2 0 Phage lysozyme PolyA_pol PF01743.20 GBG72388.1 - 0.55 10.7 3.1 0.79 10.2 3.1 1.2 1 0 0 1 1 1 0 Poly A polymerase head domain PA26 PF04636.13 GBG72388.1 - 2.3 7.0 6.7 2.8 6.8 6.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RT_RNaseH_2 PF17919.1 GBG72389.1 - 1.3e-24 86.1 0.0 2.6e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72389.1 - 6.8e-23 81.4 0.0 1.1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72389.1 - 8e-20 71.1 0.0 1.6e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72389.1 - 1.4e-17 63.5 0.4 1.4e-17 63.5 0.4 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG72389.1 - 2e-07 31.5 0.0 4.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72389.1 - 1.2e-05 25.7 0.0 2.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG72389.1 - 7.9e-05 22.4 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72389.1 - 9.7e-05 22.2 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG72389.1 - 0.037 13.9 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC_5 PF14787.6 GBG72391.1 - 0.002 17.8 0.6 0.0058 16.3 0.6 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 GBG72391.1 - 0.12 12.8 0.8 0.72 10.3 0.1 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G RVT_1 PF00078.27 GBG72392.1 - 1.8e-27 96.3 0.1 2.9e-27 95.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72392.1 - 2.8e-20 72.2 0.0 5.5e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72392.1 - 1.8e-08 34.6 0.0 4.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GAF PF01590.26 GBG72392.1 - 0.059 14.0 0.1 6.8 7.3 0.0 2.5 2 0 0 2 2 2 0 GAF domain Gluconate_2-dh3 PF13618.6 GBG72392.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 gag-asp_proteas PF13975.6 GBG72393.1 - 4.5e-06 27.1 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72393.1 - 0.0012 19.4 0.0 0.0031 18.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG72393.1 - 0.037 14.0 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG72393.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG72393.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) rve PF00665.26 GBG72393.1 - 0.11 12.7 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG72394.1 - 1.3e-30 105.4 0.0 2.7e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72394.1 - 3e-29 101.4 0.5 1.1e-28 99.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG72394.1 - 0.0029 17.9 0.1 0.093 13.0 0.0 3.2 3 0 0 3 3 3 1 Retrotransposon gag protein TerB_C PF15615.6 GBG72394.1 - 3.9 7.8 14.3 2.8 8.2 11.4 2.2 2 0 0 2 2 2 0 TerB-C domain Phage_GPO PF05929.11 GBG72394.1 - 6.8 6.2 15.5 0.57 9.7 0.1 2.8 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG72396.1 - 1.1e-84 278.9 0.0 4.8e-32 110.0 0.2 3.5 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72396.1 - 1.4e-76 253.6 1.1 1e-28 99.7 0.3 3.5 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72396.1 - 2.6e-25 89.3 0.1 5.2e-20 71.9 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72396.1 - 1.3e-17 63.6 0.2 2.7e-17 62.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG72396.1 - 0.0022 18.2 0.0 0.14 12.4 0.0 3.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG72396.1 - 0.099 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger TFIIA PF03153.13 GBG72396.1 - 0.54 10.2 37.2 0.0041 17.2 29.0 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 GBG72396.1 - 2.7 6.1 12.0 4.7 5.3 12.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_DNAp_acc PF04929.12 GBG72396.1 - 7.6 5.4 6.9 41 3.0 7.8 1.8 2 0 0 2 2 2 0 Herpes DNA replication accessory factor API5 PF05918.11 GBG72396.1 - 9.4 4.9 10.5 21 3.8 10.5 1.6 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) eIF-1a PF01176.19 GBG72398.1 - 0.089 12.6 0.1 16 5.4 0.0 2.5 2 1 0 2 2 2 0 Translation initiation factor 1A / IF-1 DPBB_1 PF03330.18 GBG72399.1 - 1.8e-10 40.9 0.1 3.2e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG72399.1 - 1.5e-07 31.3 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen Asp_protease_2 PF13650.6 GBG72401.1 - 0.00058 20.4 0.0 0.0012 19.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72401.1 - 0.00089 19.8 0.0 0.0018 18.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG72401.1 - 0.0065 16.8 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Ku_N PF03731.15 GBG72401.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain Integrase_H2C2 PF17921.1 GBG72402.1 - 2.4e-13 50.0 0.0 5.3e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG72402.1 - 5e-06 26.8 0.0 2.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72402.1 - 4.8e-05 23.3 0.1 0.00014 21.8 0.1 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG72402.1 - 0.0015 19.0 0.0 0.0035 17.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72402.1 - 0.037 14.7 0.0 0.096 13.3 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG72402.1 - 0.1 12.4 0.2 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG72404.1 - 9.3e-17 60.9 0.0 2.1e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72404.1 - 2.9e-15 56.4 0.0 5.2e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72404.1 - 4.2e-12 46.0 0.2 9e-12 44.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72404.1 - 6.5e-11 42.5 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG72404.1 - 5.3e-09 35.9 0.0 9.3e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG72404.1 - 7e-05 23.3 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72404.1 - 0.0017 19.0 0.0 0.0036 17.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG72404.1 - 0.068 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG72406.1 - 3.6e-14 52.6 0.3 7.6e-14 51.6 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG72406.1 - 0.049 13.9 0.0 2.4 8.5 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG72406.1 - 0.079 13.6 0.0 0.22 12.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG72406.1 - 0.15 12.7 0.0 0.46 11.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF913 PF06025.12 GBG72407.1 - 2.2 7.1 7.3 2.4 7.1 7.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pkinase PF00069.25 GBG72408.1 - 5.2e-30 104.7 0.1 7.2e-30 104.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG72408.1 - 5.6e-21 75.0 0.1 7.8e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RT_RNaseH_2 PF17919.1 GBG72409.1 - 1.3e-30 105.3 0.0 2.9e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72409.1 - 8.1e-27 93.6 0.0 1.8e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72409.1 - 3.7e-10 40.0 0.0 9.1e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG72409.1 - 4.8e-10 39.3 0.1 9.4e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rhamno_transf PF11316.8 GBG72409.1 - 0.031 13.6 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative rhamnosyl transferase CCDC85 PF10226.9 GBG72409.1 - 0.092 12.4 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 CCDC85 family DUF2385 PF09539.10 GBG72409.1 - 0.14 12.7 0.1 2.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) NPR3 PF03666.13 GBG72410.1 - 7.9 5.1 5.8 13 4.5 5.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pectinesterase PF01095.19 GBG72411.1 - 1.4e-59 201.3 0.7 1.7e-59 201.0 0.7 1.0 1 0 0 1 1 1 1 Pectinesterase Retrotrans_gag PF03732.17 GBG72412.1 - 0.083 13.2 0.3 0.083 13.2 0.3 2.4 3 0 0 3 3 3 0 Retrotransposon gag protein LRR_6 PF13516.6 GBG72413.1 - 5.8e-32 107.0 31.2 0.00081 19.3 0.0 15.8 18 0 0 18 18 18 11 Leucine Rich repeat LRR_4 PF12799.7 GBG72413.1 - 2.1e-20 72.4 0.0 0.058 13.9 0.0 9.5 7 2 2 10 10 10 4 Leucine Rich repeats (2 copies) F-box_5 PF18511.1 GBG72413.1 - 1.3e-11 43.8 0.6 3.1e-11 42.7 0.6 1.7 1 0 0 1 1 1 1 F-box LRR_8 PF13855.6 GBG72413.1 - 2.6e-11 43.1 2.2 0.0028 17.4 0.3 7.1 7 2 2 9 9 9 3 Leucine rich repeat LRR_1 PF00560.33 GBG72413.1 - 1.8e-07 30.7 11.1 13 6.8 0.0 10.6 10 3 0 10 10 10 1 Leucine Rich Repeat F-box-like PF12937.7 GBG72413.1 - 0.0013 18.6 1.2 0.0027 17.6 0.4 2.0 2 0 0 2 2 2 1 F-box-like Redoxin PF08534.10 GBG72414.1 - 1.1e-29 103.0 0.1 1.3e-29 102.8 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GBG72414.1 - 2.4e-09 37.2 0.0 2.8e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Dzip-like_N PF13815.6 GBG72415.1 - 4.1e-08 33.2 1.0 4.1e-08 33.2 1.0 15.9 17 3 3 21 21 21 2 Iguana/Dzip1-like DAZ-interacting protein N-terminal LRR_4 PF12799.7 GBG72416.1 - 3.6e-16 59.0 37.4 0.06 13.8 0.0 14.0 7 4 9 17 17 17 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 GBG72416.1 - 2.1e-08 33.9 2.2 3.7e-08 33.1 0.2 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GBG72416.1 - 1.7e-07 31.0 0.1 8.7e-07 28.7 0.1 2.3 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 GBG72416.1 - 5.6e-07 29.2 17.6 0.00061 19.5 0.0 9.2 8 2 1 9 9 9 1 Leucine rich repeat LRR_6 PF13516.6 GBG72416.1 - 4.8e-05 23.1 44.4 1.2 9.3 0.0 16.8 20 0 0 20 20 20 2 Leucine Rich repeat LRR_1 PF00560.33 GBG72416.1 - 0.0017 18.7 31.1 10 7.1 0.1 13.6 15 1 0 15 15 15 2 Leucine Rich Repeat Tubulin PF00091.25 GBG72417.1 - 3.4e-67 226.5 0.0 4.6e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG72417.1 - 2.7e-51 173.0 0.1 4.2e-51 172.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GBG72417.1 - 0.0074 16.0 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain RVT_1 PF00078.27 GBG72418.1 - 2.2e-30 105.8 0.0 3.4e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72418.1 - 9.4e-17 60.9 0.0 2.8e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72418.1 - 2.2e-16 59.7 0.2 6.7e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG72418.1 - 3.2e-12 46.7 0.2 1.4e-11 44.6 0.0 2.1 2 1 1 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG72418.1 - 2.9e-05 24.2 0.0 7.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG72418.1 - 8.7e-05 22.8 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG72418.1 - 0.029 15.0 0.0 0.18 12.5 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Tubulin PF00091.25 GBG72419.1 - 3.4e-67 226.5 0.0 4.6e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG72419.1 - 2.7e-51 173.0 0.1 4.2e-51 172.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GBG72419.1 - 0.0074 16.0 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain Spectrin PF00435.21 GBG72420.1 - 0.075 13.5 3.3 0.22 12.0 0.1 2.5 2 0 0 2 2 2 0 Spectrin repeat NACHT_N PF17100.5 GBG72420.1 - 0.4 10.5 4.0 0.93 9.3 2.6 2.0 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase Pup PF05639.11 GBG72420.1 - 3.8 8.5 5.3 17 6.4 0.3 2.4 1 1 1 2 2 2 0 Pup-like protein Glycos_transf_2 PF00535.26 GBG72421.1 - 6.3e-21 74.9 0.0 8.6e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG72421.1 - 5e-08 33.1 0.0 6.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GBG72421.1 - 8.3e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 GBG72421.1 - 0.0096 16.4 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PRiA4_ORF3 PF07929.11 GBG72423.1 - 2.6e-22 79.3 0.0 1.7e-21 76.7 0.0 2.2 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein adh_short_C2 PF13561.6 GBG72424.1 - 2.2e-55 187.8 0.1 4.1e-55 186.9 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GBG72424.1 - 4.5e-40 137.2 0.0 8.8e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RT_RNaseH PF17917.1 GBG72424.1 - 2.2e-19 69.7 0.0 1.2e-18 67.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72424.1 - 5.7e-17 61.6 0.6 1.6e-16 60.1 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG72424.1 - 8.9e-17 61.0 0.0 2.3e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72424.1 - 5.1e-06 26.7 0.0 1.6e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain KR PF08659.10 GBG72424.1 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 KR domain Retrotrans_gag PF03732.17 GBG72424.1 - 0.033 14.5 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Topo_Zn_Ribbon PF08272.11 GBG72425.1 - 0.051 13.2 0.3 0.051 13.2 0.3 2.0 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG72425.1 - 0.18 11.9 1.8 0.47 10.6 1.8 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-met PF12874.7 GBG72426.1 - 4.2e-07 30.2 15.9 8.4e-05 22.8 1.2 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GBG72426.1 - 0.0011 19.2 1.6 0.0011 19.2 1.6 4.0 4 0 0 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GBG72426.1 - 0.015 15.6 1.0 0.015 15.6 1.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-SCNM1 PF15803.5 GBG72426.1 - 1.4 8.6 6.4 1.9 8.2 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 CLN3 PF02487.17 GBG72426.1 - 2.9 6.8 15.0 0.042 12.9 6.9 2.0 2 0 0 2 2 2 0 CLN3 protein DUF4407 PF14362.6 GBG72426.1 - 3.6 6.9 9.6 10 5.3 9.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3142 PF11340.8 GBG72427.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) Pox_F11 PF04943.12 GBG72428.1 - 0.038 13.1 0.1 0.056 12.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein DUF287 PF03384.14 GBG72428.1 - 0.11 12.8 0.5 0.32 11.4 0.5 1.8 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 Histone PF00125.24 GBG72431.1 - 1.1e-22 80.8 0.5 1.1e-22 80.8 0.5 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG72431.1 - 0.12 12.8 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 CENP-S protein WW PF00397.26 GBG72434.1 - 3.8e-22 78.0 10.6 3.3e-11 43.0 1.5 2.6 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 GBG72434.1 - 0.15 12.3 1.5 0.69 10.2 1.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain DUF3040 PF11239.8 GBG72434.1 - 6.6 7.1 7.4 20 5.6 7.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF1838 PF08894.11 GBG72436.1 - 0.041 13.6 0.1 0.087 12.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1838) DUF1838 PF08894.11 GBG72437.1 - 0.041 13.6 0.1 0.087 12.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1838) Borrelia_P83 PF05262.11 GBG72439.1 - 0.15 10.5 8.2 0.19 10.2 8.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Casc1_N PF15927.5 GBG72439.1 - 0.17 11.6 16.0 0.27 10.9 16.0 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus NINJA_B PF16136.5 GBG72439.1 - 0.29 11.5 14.2 0.042 14.2 9.9 1.8 2 0 0 2 2 2 0 Putative nuclear localisation signal AP1AR PF15745.5 GBG72439.1 - 0.44 10.1 11.9 0.72 9.4 11.9 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein TPD PF14811.6 GBG72439.1 - 0.44 10.4 2.9 1.1 9.1 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function TPD sequence-motif SpoVR PF04293.13 GBG72439.1 - 0.54 8.9 6.1 0.72 8.5 6.1 1.1 1 0 0 1 1 1 0 SpoVR like protein CCDC-167 PF15188.6 GBG72439.1 - 1.7 9.1 11.9 3.3 8.1 11.9 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 MCU PF04678.13 GBG72439.1 - 3.4 7.7 8.3 6.3 6.9 8.3 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter RVT_1 PF00078.27 GBG72440.1 - 4.2e-33 114.7 0.0 6.4e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OPA3 PF07047.12 GBG72441.1 - 3.7e-05 23.5 0.1 6.4e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) bZIP_1 PF00170.21 GBG72441.1 - 0.014 15.5 5.3 0.021 14.9 5.3 1.2 1 0 0 1 1 1 0 bZIP transcription factor SGL PF08450.12 GBG72442.1 - 3.8e-64 216.6 0.0 5.1e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_2 PF13360.6 GBG72442.1 - 0.088 12.4 0.1 2.8 7.5 0.0 2.5 2 1 0 2 2 2 0 PQQ-like domain LisH PF08513.11 GBG72445.1 - 0.0064 16.4 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 LisH RT_RNaseH_2 PF17919.1 GBG72447.1 - 1.8e-30 104.9 0.0 6.9e-15 54.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72447.1 - 1.9e-27 96.3 0.0 3.4e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72447.1 - 3.3e-27 94.8 0.0 7e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PPR PF01535.20 GBG72448.1 - 2.3e-74 240.6 45.1 3.4e-08 33.2 0.1 15.0 14 0 0 14 14 14 13 PPR repeat PPR_2 PF13041.6 GBG72448.1 - 3.4e-70 232.1 26.6 7.1e-12 45.3 0.2 11.3 5 2 7 12 12 12 11 PPR repeat family PPR_1 PF12854.7 GBG72448.1 - 2.9e-57 190.0 1.5 8e-06 25.5 0.0 13.3 13 0 0 13 13 13 10 PPR repeat PPR_3 PF13812.6 GBG72448.1 - 2.7e-51 171.5 0.0 1.6e-10 40.9 0.0 8.5 7 2 2 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG72448.1 - 1.6e-17 63.6 0.4 2.6e-07 30.2 0.0 4.7 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP Clathrin PF00637.20 GBG72448.1 - 7.6e-06 25.9 0.1 6.7 6.6 0.0 5.0 5 0 0 5 5 5 1 Region in Clathrin and VPS Smr PF01713.21 GBG72448.1 - 0.0022 18.3 0.0 0.0067 16.8 0.0 1.8 1 0 0 1 1 1 1 Smr domain TPR_6 PF13174.6 GBG72448.1 - 1.5 9.6 3.2 49 4.9 1.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 GBG72449.1 - 1.3e-74 241.4 45.1 3.3e-08 33.2 0.1 15.0 14 0 0 14 14 14 13 PPR repeat PPR_2 PF13041.6 GBG72449.1 - 2.4e-71 235.7 27.5 6.8e-12 45.4 0.3 11.3 5 2 7 12 12 12 11 PPR repeat family PPR_1 PF12854.7 GBG72449.1 - 1.3e-57 191.2 1.0 7.7e-06 25.5 0.0 13.2 14 0 0 14 14 14 10 PPR repeat PPR_3 PF13812.6 GBG72449.1 - 1.9e-51 172.0 0.0 1.5e-10 41.0 0.0 8.5 7 2 2 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG72449.1 - 1.3e-17 63.9 0.4 2.5e-07 30.3 0.0 4.7 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP Clathrin PF00637.20 GBG72449.1 - 6.1e-06 26.2 0.1 6.4 6.7 0.0 5.0 5 0 0 5 5 5 1 Region in Clathrin and VPS Smr PF01713.21 GBG72449.1 - 0.0021 18.4 0.0 0.0064 16.8 0.0 1.9 1 0 0 1 1 1 1 Smr domain TPR_6 PF13174.6 GBG72449.1 - 1.3 9.8 3.2 47 4.9 1.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG72449.1 - 2.2 8.6 4.2 2 8.7 1.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG72449.1 - 4.8 7.2 8.2 5.4 7.0 2.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Chor_lyase PF04345.13 GBG72450.1 - 0.053 13.2 0.0 7.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Chorismate lyase NAD_binding_5 PF07994.12 GBG72451.1 - 6.1e-139 462.9 0.0 7e-139 462.7 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 GBG72451.1 - 1.5e-46 157.1 0.0 2.7e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF3148 PF11347.8 GBG72451.1 - 0.085 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) DUF659 PF04937.15 GBG72452.1 - 1.9e-40 138.2 0.0 3.6e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG72452.1 - 2.4e-07 30.4 0.7 6.4e-07 29.1 0.7 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG72452.1 - 0.03 14.2 3.9 0.091 12.7 3.9 1.9 1 0 0 1 1 1 0 AT hook motif Pox_A_type_inc PF04508.12 GBG72452.1 - 0.17 11.8 2.2 0.6 10.1 2.2 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF659 PF04937.15 GBG72453.1 - 1.7e-18 66.9 0.1 2.5e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) NAD_binding_11 PF14833.6 GBG72453.1 - 0.04 14.2 0.2 0.12 12.6 0.1 1.9 1 1 1 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DDE_Tnp_IS66 PF03050.14 GBG72453.1 - 0.056 12.9 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 Transposase IS66 family rve PF00665.26 GBG72454.1 - 3.8e-09 36.8 0.0 1.1e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG72454.1 - 0.0028 17.9 0.2 0.011 16.0 0.2 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG72454.1 - 0.0096 15.7 0.7 0.029 14.1 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Lipin_mid PF16876.5 GBG72454.1 - 0.14 12.3 1.2 0.42 10.8 0.0 2.3 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain NT-C2 PF10358.9 GBG72454.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2497 PF10691.9 GBG72454.1 - 1.6 9.2 4.7 0.46 10.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) TFIIA PF03153.13 GBG72454.1 - 6.4 6.7 16.4 0.79 9.6 10.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit C2 PF00168.30 GBG72455.1 - 3.2e-42 143.0 0.0 1e-23 83.6 0.0 2.8 3 0 0 3 3 3 2 C2 domain VASt PF16016.5 GBG72455.1 - 8.6e-28 97.7 0.1 2e-27 96.5 0.0 1.7 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GBG72455.1 - 3.2e-15 56.0 0.0 9.7e-14 51.2 0.0 2.9 2 1 0 2 2 2 1 GRAM domain YopE_N PF09020.10 GBG72455.1 - 0.3 11.4 1.7 0.83 9.9 1.7 1.7 1 0 0 1 1 1 0 YopE, N terminal PRCC PF10253.9 GBG72456.1 - 4.3e-13 50.5 1.4 4.3e-13 50.5 1.4 2.7 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting GTP_EFTU PF00009.27 GBG72457.1 - 2.1e-35 122.0 0.9 6.1e-34 117.3 0.9 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GBG72457.1 - 1.1e-26 93.0 0.1 2.9e-26 91.6 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 GBG72457.1 - 1.5e-08 34.7 0.0 3.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG72457.1 - 1e-05 25.5 0.1 0.0082 16.1 0.0 2.5 1 1 1 2 2 2 2 RsgA GTPase IF2_N PF04760.15 GBG72457.1 - 0.00022 21.0 1.2 0.00078 19.2 0.1 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 GBG72457.1 - 0.00023 21.5 4.8 0.0063 16.9 0.0 3.6 2 1 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.22 GBG72457.1 - 0.00048 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.21 GBG72457.1 - 0.00051 19.6 0.0 0.00094 18.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 GBG72457.1 - 0.00053 19.7 0.0 0.0025 17.5 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GBG72457.1 - 0.0007 19.1 0.0 0.0029 17.1 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GBG72457.1 - 0.0065 16.0 0.0 0.018 14.6 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 GBG72457.1 - 0.0099 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GBG72457.1 - 0.016 15.3 0.1 0.72 9.9 0.0 2.7 2 1 1 3 3 3 0 Dynamin family DMA PF03474.14 GBG72457.1 - 0.26 10.9 1.6 0.57 9.8 1.6 1.6 1 0 0 1 1 1 0 DMRTA motif Myb_DNA-bind_4 PF13837.6 GBG72458.1 - 3.8e-06 27.2 0.7 7.3e-06 26.3 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72458.1 - 0.081 13.3 0.4 0.17 12.2 0.4 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TraG_N PF07916.11 GBG72458.1 - 6.6 5.5 13.5 13 4.5 13.5 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Retrotrans_gag PF03732.17 GBG72459.1 - 6.4e-05 23.1 0.1 0.00017 21.8 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Ribosomal_S8e PF01201.22 GBG72462.1 - 6.3e-48 162.4 0.2 2.1e-47 160.8 0.0 1.7 1 1 1 2 2 2 1 Ribosomal protein S8e zf-ZPR1 PF03367.13 GBG72463.1 - 2.5e-24 85.9 0.0 3.9e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 ZPR1 zinc-finger domain HTH_26 PF13443.6 GBG72463.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain EF-hand_1 PF00036.32 GBG72464.1 - 4.4e-29 97.8 5.0 4.7e-06 25.8 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GBG72464.1 - 1.5e-26 92.6 1.5 5.6e-13 49.1 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG72464.1 - 1.6e-22 77.9 4.8 1.2e-05 24.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 GBG72464.1 - 5e-22 75.9 3.4 1.4e-06 27.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GBG72464.1 - 1.4e-21 76.1 5.2 5.1e-08 32.6 0.2 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 GBG72464.1 - 0.00014 22.1 0.1 0.018 15.3 0.0 3.3 3 1 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 GBG72464.1 - 0.00073 19.8 0.0 0.1 12.9 0.0 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 GBG72464.1 - 0.0073 14.9 0.0 0.012 14.2 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Caleosin PF05042.13 GBG72464.1 - 0.0083 16.1 0.0 0.61 10.0 0.0 2.5 2 1 0 2 2 2 1 Caleosin related protein EF-hand_11 PF08976.11 GBG72464.1 - 0.019 15.8 0.0 0.052 14.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Dockerin_1 PF00404.18 GBG72464.1 - 0.04 14.1 0.0 12 6.2 0.0 3.3 3 0 0 3 3 3 0 Dockerin type I domain EF-hand_4 PF12763.7 GBG72464.1 - 0.041 13.8 0.6 5.4 7.0 0.0 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3741 PF12552.8 GBG72464.1 - 0.047 13.7 0.5 0.52 10.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3741) EF-hand_10 PF14788.6 GBG72464.1 - 0.18 11.7 2.6 0.96 9.4 0.1 2.6 3 0 0 3 3 3 0 EF hand SNN_cytoplasm PF09051.10 GBG72464.1 - 1.1 9.2 3.8 32 4.5 0.0 3.3 3 0 0 3 3 3 0 Stannin cytoplasmic Phi29_Phage_SSB PF17427.2 GBG72465.1 - 2.9 8.1 9.3 4.3 7.5 0.4 2.7 1 1 1 2 2 2 0 Phage Single-stranded DNA-binding protein Phi29_Phage_SSB PF17427.2 GBG72466.1 - 6 7.1 9.1 4.7 7.4 1.9 2.6 1 1 1 2 2 2 0 Phage Single-stranded DNA-binding protein TTL PF03133.15 GBG72467.1 - 2.3e-51 174.7 0.1 4.1e-51 173.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family LRR_4 PF12799.7 GBG72467.1 - 5.3e-08 33.0 2.1 0.0025 18.2 0.0 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG72467.1 - 5.4e-05 22.9 1.3 0.19 11.5 0.1 2.8 2 0 0 2 2 2 2 Leucine rich repeat PsbQ PF05757.11 GBG72468.1 - 0.45 10.2 6.1 0.65 9.7 6.1 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) SID-1_RNA_chan PF13965.6 GBG72468.1 - 4.8 5.5 10.3 0.072 11.5 0.3 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 PfkB PF00294.24 GBG72471.1 - 5.6e-79 265.6 0.0 6.4e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase LRR_4 PF12799.7 GBG72472.1 - 6.3e-14 51.9 17.4 5.7e-05 23.4 4.8 5.2 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG72472.1 - 9.3e-13 47.7 8.5 3.7e-06 26.6 0.9 3.6 2 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 GBG72472.1 - 0.039 13.5 5.3 0.7 9.4 3.8 2.7 2 1 0 2 2 2 0 Leucine-rich repeat RsmF_methylt_CI PF17126.5 GBG72472.1 - 0.057 13.5 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain Carbam_trans_C PF16861.5 GBG72473.1 - 0.17 11.5 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 Carbamoyltransferase C-terminus Radial_spoke PF04712.12 GBG72474.1 - 1.8e-124 416.4 0.0 1.8e-124 416.4 0.0 2.0 1 1 1 2 2 2 1 Radial spokehead-like protein Pkinase PF00069.25 GBG72475.1 - 1.8e-70 237.3 0.1 3e-70 236.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG72475.1 - 4.3e-34 118.0 0.0 6.9e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG72475.1 - 3.3e-05 23.3 0.2 0.00036 19.9 0.1 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GBG72475.1 - 0.0011 17.9 6.8 0.028 13.2 0.0 3.0 2 1 1 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 GBG72475.1 - 0.0012 17.9 2.3 0.0028 16.7 2.3 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GBG72475.1 - 0.0013 18.1 1.0 0.0035 16.7 1.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-G-binding_N PF07299.11 GBG72475.1 - 0.01 16.3 0.8 8.1 7.0 0.0 2.8 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal FeoB_N PF02421.18 GBG72475.1 - 0.19 11.2 0.4 1 8.9 0.3 1.9 1 1 1 2 2 2 0 Ferrous iron transport protein B APH PF01636.23 GBG72475.1 - 0.41 10.5 10.7 0.55 10.1 0.0 3.4 2 2 1 3 3 3 0 Phosphotransferase enzyme family Sigma70_r4 PF04545.16 GBG72476.1 - 4.5e-06 26.1 0.1 7.9e-06 25.3 0.1 1.5 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 GBG72476.1 - 1.9e-05 24.2 0.3 0.00033 20.3 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 GBG72476.1 - 0.053 13.4 0.9 0.2 11.5 0.1 1.9 1 1 1 2 2 2 0 ECF sigma factor Pec_lyase_C PF00544.19 GBG72477.1 - 1.1e-23 83.9 3.5 1.3e-22 80.5 3.5 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG72477.1 - 5.8e-07 29.5 4.0 1.1e-06 28.6 4.0 1.4 1 0 0 1 1 1 1 Right handed beta helix region Pectate_lyase_3 PF12708.7 GBG72477.1 - 0.0098 15.8 0.4 0.021 14.7 0.4 1.5 1 0 0 1 1 1 1 Pectate lyase superfamily protein Phosphorylase PF00343.20 GBG72478.1 - 7.7e-295 979.8 0.0 1.6e-167 558.9 0.1 2.1 2 0 0 2 2 2 2 Carbohydrate phosphorylase YL1 PF05764.13 GBG72478.1 - 9.5e-07 29.2 10.8 1.6e-06 28.5 10.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein EPL1 PF10513.9 GBG72478.1 - 0.004 17.5 5.2 0.011 16.1 5.2 1.7 2 0 0 2 2 2 1 Enhancer of polycomb-like SR-25 PF10500.9 GBG72478.1 - 0.032 13.8 13.9 0.082 12.5 13.9 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 GBG72478.1 - 0.039 12.3 13.9 0.057 11.7 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 GBG72478.1 - 0.26 11.4 2.1 0.48 10.5 2.1 1.4 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 GBG72478.1 - 0.54 10.7 7.8 1.1 9.6 7.8 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 GBG72478.1 - 0.64 8.2 22.5 0.91 7.7 22.5 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG72478.1 - 0.94 9.8 14.1 1.9 8.8 14.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CobT PF06213.12 GBG72478.1 - 0.96 8.8 20.5 1.7 8.0 20.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3464 PF11947.8 GBG72478.1 - 1.2 8.9 12.2 2.3 8.0 12.2 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Neur_chan_memb PF02932.16 GBG72478.1 - 1.6 8.8 6.4 2.7 8.0 6.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GAGA_bind PF06217.12 GBG72478.1 - 3.1 8.0 11.7 5.1 7.3 11.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SLC12 PF03522.15 GBG72478.1 - 3.3 6.6 9.9 5.1 6.0 9.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF2052 PF09747.9 GBG72478.1 - 3.8 7.6 23.4 6.8 6.8 23.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 GBG72478.1 - 5 5.8 11.1 7.6 5.2 11.1 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG72478.1 - 6.5 5.4 10.2 7.2 5.3 8.9 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG72480.1 - 0.0075 14.6 0.2 0.009 14.3 0.2 1.0 1 0 0 1 1 1 1 Nop14-like family TM231 PF10149.9 GBG72480.1 - 0.022 14.1 0.9 0.026 13.9 0.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 Rubella_E2 PF05749.11 GBG72480.1 - 0.12 11.8 0.7 0.16 11.4 0.7 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Sec23_trunk PF04811.15 GBG72481.1 - 9.2e-57 192.4 0.0 1.4e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GBG72481.1 - 3.4e-26 91.8 0.2 6.2e-26 91.0 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 GBG72481.1 - 1.8e-21 75.9 0.0 3.4e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GBG72481.1 - 8.9e-17 60.9 6.9 8.9e-17 60.9 6.9 1.8 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GBG72481.1 - 1.1e-11 44.4 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat zinc_ribbon_10 PF10058.9 GBG72481.1 - 0.1 12.3 1.5 0.24 11.2 1.5 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein VWA_2 PF13519.6 GBG72481.1 - 0.13 12.9 0.0 0.53 11.0 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain Trypsin_2 PF13365.6 GBG72482.1 - 2.5e-07 31.7 0.0 4.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GBG72482.1 - 1.1e-06 28.6 0.3 1.5e-06 28.2 0.3 1.1 1 0 0 1 1 1 1 Trypsin Peptidase_S29 PF02907.15 GBG72482.1 - 0.0047 16.7 0.1 0.0068 16.2 0.1 1.2 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 GBG72482.1 - 0.041 12.5 0.5 0.053 12.2 0.5 1.1 1 0 0 1 1 1 0 Peptidase S46 RT_RNaseH_2 PF17919.1 GBG72483.1 - 3e-26 91.3 0.0 7e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72483.1 - 3e-24 85.3 0.0 6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72483.1 - 2.2e-17 63.3 0.0 3.4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3807 PF12720.7 GBG72483.1 - 0.2 11.9 10.6 0.33 11.2 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Nop14 PF04147.12 GBG72483.1 - 2.6 6.1 21.7 3.9 5.6 21.7 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 GBG72483.1 - 3 8.1 13.0 5.3 7.3 13.0 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG72483.1 - 5.6 6.3 25.4 8.2 5.7 25.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG72483.1 - 8.4 5.6 24.8 12 5.1 24.8 1.1 1 0 0 1 1 1 0 BUD22 WD40 PF00400.32 GBG72484.1 - 1e-33 114.8 21.0 6e-05 23.7 1.3 12.3 11 2 0 11 11 11 7 WD domain, G-beta repeat RT_RNaseH_2 PF17919.1 GBG72484.1 - 2.4e-25 88.5 0.0 5.6e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72484.1 - 6.3e-24 84.3 0.0 2.2e-23 82.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ANAPC4_WD40 PF12894.7 GBG72484.1 - 0.0011 19.2 0.4 0.6 10.5 0.0 4.3 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG72484.1 - 0.02 14.2 0.2 0.46 9.7 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain PALB2_WD40 PF16756.5 GBG72484.1 - 0.042 12.8 0.0 0.64 8.9 0.0 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 GBG72484.1 - 0.56 8.8 6.2 5.1 5.6 0.2 3.7 3 2 0 3 3 3 0 Nucleoporin Nup120/160 Mito_carr PF00153.27 GBG72485.1 - 1.4e-67 223.7 0.1 9.7e-24 83.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Nop14 PF04147.12 GBG72486.1 - 7.8 4.6 52.2 8.7 4.4 52.2 1.0 1 0 0 1 1 1 0 Nop14-like family AIP3 PF03915.13 GBG72487.1 - 0.00016 20.9 2.1 0.00027 20.2 2.1 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Retrotrans_gag PF03732.17 GBG72487.1 - 0.012 15.9 3.4 0.013 15.7 0.1 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein TMEM247 PF15444.6 GBG72487.1 - 0.098 12.7 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 247 Metal_resist PF13801.6 GBG72487.1 - 10 6.4 20.3 1.8 8.8 4.1 2.4 2 0 0 2 2 2 0 Heavy-metal resistance AIP3 PF03915.13 GBG72488.1 - 0.00017 20.8 2.1 0.00029 20.1 2.1 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Retrotrans_gag PF03732.17 GBG72488.1 - 0.012 15.9 3.4 0.014 15.7 0.1 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein TMEM247 PF15444.6 GBG72488.1 - 0.09 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 BAR PF03114.18 GBG72492.1 - 0.76 9.4 7.7 1.2 8.7 7.7 1.2 1 0 0 1 1 1 0 BAR domain Glyco_transf_8 PF01501.20 GBG72493.1 - 4.4e-60 203.4 0.0 2.2e-59 201.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GBG72493.1 - 2.5e-08 33.7 0.1 4.8e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 MTP18 PF10558.9 GBG72493.1 - 0.038 13.9 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) Glyco_transf_8 PF01501.20 GBG72494.1 - 4.3e-60 203.4 0.0 2.1e-59 201.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GBG72494.1 - 2.9e-08 33.4 0.1 4.8e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 MTP18 PF10558.9 GBG72494.1 - 0.043 13.8 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) zf-CCHC PF00098.23 GBG72495.1 - 0.00052 20.0 1.6 0.0011 18.9 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Keratin_assoc PF09775.9 GBG72496.1 - 2.6e-42 143.5 4.9 2.8e-42 143.4 4.9 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 DUF2976 PF11190.8 GBG72496.1 - 0.052 13.4 3.2 0.057 13.2 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) PHO4 PF01384.20 GBG72496.1 - 0.057 12.5 0.8 0.064 12.3 0.8 1.2 1 0 0 1 1 1 0 Phosphate transporter family SirB PF04247.12 GBG72496.1 - 0.28 11.3 7.8 0.64 10.1 7.6 1.6 1 1 1 2 2 2 0 Invasion gene expression up-regulator, SirB Oxidored_q3 PF00499.20 GBG72496.1 - 0.3 10.8 6.6 1.6 8.5 6.6 2.1 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 ECF_trnsprt PF12822.7 GBG72496.1 - 0.37 10.9 5.3 0.61 10.2 5.3 1.4 1 1 0 1 1 1 0 ECF transporter, substrate-specific component DUF3792 PF12670.7 GBG72496.1 - 4.6 7.4 10.8 3.5 7.8 5.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) Glyco_hydro_28 PF00295.17 GBG72498.1 - 4.9e-46 157.3 0.1 6.8e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 GBG72498.1 - 2.3e-06 27.6 1.0 0.0047 16.8 0.0 3.1 2 1 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.6 GBG72498.1 - 0.027 14.3 5.8 0.097 12.5 5.8 1.8 1 1 0 1 1 1 0 Right handed beta helix region DUF2457 PF10446.9 GBG72498.1 - 0.042 13.0 8.8 0.061 12.5 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.11 GBG72498.1 - 0.27 9.3 2.2 0.39 8.7 2.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4611 PF15387.6 GBG72498.1 - 1.7 8.9 7.1 2.8 8.2 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 GBG72498.1 - 5.3 7.5 9.6 9.8 6.6 9.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Carb_anhydrase PF00194.21 GBG72499.1 - 4.4e-35 121.4 0.0 9e-35 120.4 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 GBG72501.1 - 4.2e-34 118.2 0.0 6.2e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase PAF-AH_p_II PF03403.13 GBG72502.1 - 9.4e-57 192.2 0.0 1.2e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 GBG72502.1 - 1.1e-07 31.1 0.3 1.7e-06 27.2 0.3 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 GBG72502.1 - 3.5e-05 23.2 0.2 0.0042 16.4 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 GBG72502.1 - 0.00014 21.0 0.0 0.019 14.0 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_6 PF12697.7 GBG72502.1 - 0.0003 21.5 0.0 0.0004 21.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG72502.1 - 0.00045 19.9 0.0 0.00096 18.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 GBG72502.1 - 0.004 16.9 0.0 0.15 11.8 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 GBG72502.1 - 0.0052 15.5 0.1 0.028 13.1 0.0 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 GBG72502.1 - 0.054 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 GBG72502.1 - 0.054 13.4 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 GBG72502.1 - 0.062 12.8 0.1 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lzipper-MIP1 PF14389.6 GBG72502.1 - 0.069 13.4 1.0 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Nop14 PF04147.12 GBG72503.1 - 0.0018 16.6 21.1 0.0021 16.4 21.1 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG72503.1 - 0.0031 17.0 23.2 0.0031 17.0 23.2 1.5 2 0 0 2 2 2 1 SDA1 ZapB PF06005.12 GBG72504.1 - 0.019 15.4 0.5 5 7.7 0.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB TMCO5 PF14992.6 GBG72504.1 - 0.032 13.8 1.9 0.041 13.5 0.2 1.7 1 1 1 2 2 2 0 TMCO5 family KELK PF15796.5 GBG72504.1 - 1 9.8 4.6 1.2 9.6 0.6 2.7 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RVT_1 PF00078.27 GBG72505.1 - 2.4e-26 92.6 0.0 3.6e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG72505.1 - 1.5e-12 47.2 0.0 3.5e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG72505.1 - 0.01 16.4 0.0 0.021 15.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG72506.1 - 2.4e-26 91.7 0.0 6.1e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72506.1 - 3.5e-24 85.1 0.0 1.5e-23 83.0 0.0 2.1 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72506.1 - 6.6e-18 64.6 0.2 1.3e-17 63.7 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG72506.1 - 2.5e-11 43.5 0.0 3e-08 33.5 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG72506.1 - 0.02 15.1 0.5 0.076 13.3 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG72507.1 - 4.3e-22 78.4 0.0 8.2e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72507.1 - 9.2e-21 73.8 0.0 2.3e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG72507.1 - 0.012 16.2 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG72507.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2385 PF09539.10 GBG72508.1 - 0.004 17.7 0.1 0.22 12.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2385) HlyIII PF03006.20 GBG72509.1 - 8e-39 133.7 7.2 8.9e-39 133.5 7.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related CD225 PF04505.12 GBG72509.1 - 0.037 14.1 0.9 0.73 10.0 0.0 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Peptidase_M16_M PF16187.5 GBG72511.1 - 1e-91 307.2 0.2 1.5e-91 306.6 0.2 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GBG72511.1 - 1.3e-36 125.8 0.7 2.7e-36 124.8 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GBG72511.1 - 4.6e-25 88.7 0.8 6.6e-11 42.5 0.0 4.4 4 1 1 5 5 5 2 Peptidase M16 inactive domain DDE_Tnp_4 PF13359.6 GBG72512.1 - 7.4e-26 90.7 0.0 1e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72512.1 - 8.4e-12 45.1 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72512.1 - 0.24 11.0 0.5 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain ubiquitin PF00240.23 GBG72513.1 - 5e-34 115.9 0.6 9e-34 115.1 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 GBG72513.1 - 8e-26 90.0 1.7 8e-26 90.0 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 GBG72513.1 - 2.8e-16 59.1 0.8 2.8e-16 59.1 0.8 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GBG72513.1 - 2.1e-05 24.9 0.4 0.00019 21.8 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GBG72513.1 - 0.00046 20.3 0.9 0.001 19.2 0.9 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GBG72513.1 - 0.0045 17.5 1.0 0.0065 17.0 1.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 GBG72513.1 - 0.0065 16.4 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GBG72513.1 - 0.015 15.7 1.8 0.017 15.5 0.1 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 GBG72513.1 - 0.03 14.4 1.1 6.2 6.9 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain AlcCBM31 PF11606.8 GBG72513.1 - 0.07 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein Plexin_cytopl PF08337.12 GBG72513.1 - 0.12 11.0 3.3 2.2 6.8 0.2 2.6 2 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain RVT_1 PF00078.27 GBG72515.1 - 1.7e-37 129.1 0.0 2.9e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG72515.1 - 1.8e-08 35.0 5.7 6.1e-08 33.3 5.7 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Clathrin_bdg PF15045.6 GBG72515.1 - 0.86 9.7 2.9 1.1 9.3 1.0 2.2 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking MID_MedPIWI PF18296.1 GBG72516.1 - 0.044 13.6 7.1 1.8 8.3 0.3 2.5 2 0 0 2 2 2 0 MID domain of medPIWI SpoIIIAH PF12685.7 GBG72516.1 - 0.75 9.6 21.7 3.4 7.4 10.6 2.5 2 0 0 2 2 2 0 SpoIIIAH-like protein Utp14 PF04615.13 GBG72516.1 - 1.2 7.6 16.6 0.71 8.4 6.0 2.2 2 0 0 2 2 2 0 Utp14 protein CPSF100_C PF13299.6 GBG72516.1 - 1.6 8.8 8.6 5 7.3 1.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TCP PF03634.13 GBG72516.1 - 3.2 8.3 10.7 4.6 7.8 1.2 2.3 2 0 0 2 2 2 0 TCP family transcription factor FAM60A PF15396.6 GBG72516.1 - 4 7.4 11.2 6.6 6.7 3.3 2.4 2 0 0 2 2 2 0 Protein Family FAM60A SLC12 PF03522.15 GBG72516.1 - 7.8 5.4 12.6 4.8 6.1 3.9 2.1 2 0 0 2 2 2 0 Solute carrier family 12 PPP4R2 PF09184.11 GBG72516.1 - 7.8 6.0 31.5 3.6 7.1 18.5 2.4 2 0 0 2 2 2 0 PPP4R2 TT_ORF1 PF02956.14 GBG72516.1 - 9.5 4.8 14.1 3.4 6.2 1.1 2.1 2 0 0 2 2 2 0 TT viral orf 1 Asp_protease_2 PF13650.6 GBG72517.1 - 4.5e-05 24.0 0.0 0.00015 22.3 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG72517.1 - 0.00015 21.5 0.0 0.00073 19.3 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG72517.1 - 0.00039 20.9 0.0 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG72517.1 - 0.047 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF4596 PF15363.6 GBG72517.1 - 0.064 13.5 0.8 0.35 11.1 0.8 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) RT_RNaseH_2 PF17919.1 GBG72518.1 - 4.8e-27 93.9 0.0 7.9e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72518.1 - 8.8e-26 90.2 0.0 1.4e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72518.1 - 9.6e-18 64.1 0.6 3e-17 62.4 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG72518.1 - 0.17 12.2 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG72519.1 - 2.4e-19 69.8 0.0 3.7e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72519.1 - 3.4e-16 59.1 0.7 1.2e-15 57.3 0.1 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG72519.1 - 5.1e-13 49.3 0.1 1.8e-12 47.5 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG72519.1 - 5.2e-13 48.7 0.0 1.4e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG72519.1 - 9.1e-05 22.6 0.1 0.00022 21.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG72522.1 - 5.1e-12 46.0 5.5 8.1e-12 45.4 5.5 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72522.1 - 0.0085 16.4 2.6 0.015 15.6 2.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG72522.1 - 0.014 15.6 1.5 0.028 14.7 1.5 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 GBG72522.1 - 0.048 14.6 2.4 0.072 14.1 2.4 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG72522.1 - 0.79 10.0 4.9 2.3 8.5 4.9 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Tyrosinase PF00264.20 GBG72523.1 - 1.2e-29 104.2 11.0 3.2e-16 60.3 0.5 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG72523.1 - 1.6e-15 56.6 0.1 2.9e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain PPO1_KFDV PF12143.8 GBG72523.1 - 0.0002 21.5 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF_B2219) gag-asp_proteas PF13975.6 GBG72524.1 - 0.00028 21.4 0.0 0.00076 20.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72524.1 - 0.0014 19.3 0.0 0.0034 18.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG72524.1 - 0.0022 18.3 0.1 0.0065 16.8 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG72524.1 - 0.0069 16.6 0.1 0.029 14.6 0.1 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG72524.1 - 0.065 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease BUD22 PF09073.10 GBG72525.1 - 0.00051 19.5 27.8 0.00068 19.1 27.8 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 GBG72525.1 - 0.0041 15.4 33.6 0.0054 15.0 33.6 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG72525.1 - 0.051 13.0 39.2 0.074 12.5 39.2 1.1 1 0 0 1 1 1 0 SDA1 DUF4710 PF15828.5 GBG72525.1 - 0.15 12.2 12.1 0.44 10.7 12.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) CDC45 PF02724.14 GBG72525.1 - 0.33 9.2 28.1 0.46 8.7 28.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GBG72525.1 - 0.78 8.1 38.1 1.1 7.6 38.1 1.1 1 0 0 1 1 1 0 Mpp10 protein SRP72 PF08492.12 GBG72525.1 - 1.1 9.7 11.1 3.1 8.3 11.1 1.7 1 0 0 1 1 1 0 SRP72 RNA-binding domain DUF2201_N PF13203.6 GBG72525.1 - 1.2 8.7 10.7 0.088 12.4 5.5 1.7 2 1 0 2 2 2 0 Putative metallopeptidase domain DUF913 PF06025.12 GBG72525.1 - 3.3 6.6 8.7 5.5 5.9 8.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_11 PF13086.6 GBG72525.1 - 3.6 7.3 7.7 4.8 6.9 7.7 1.2 1 0 0 1 1 1 0 AAA domain Tyrosinase PF00264.20 GBG72526.1 - 3.5e-29 102.7 12.1 8.9e-16 58.8 0.9 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG72526.1 - 2e-15 56.3 0.1 4e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain Peptidase_M76 PF09768.9 GBG72527.1 - 1.7e-08 34.4 0.0 2.1e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase M76 family DDE_5 PF13546.6 GBG72528.1 - 0.029 13.7 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 GBG72529.1 - 3.3e-32 110.5 0.0 1e-31 108.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72529.1 - 1.6e-29 102.3 0.2 3.5e-29 101.2 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG72529.1 - 2.1e-15 57.1 0.0 3.2e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG72529.1 - 3.2e-14 53.3 0.0 3.1e-06 27.7 0.0 2.9 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG72529.1 - 1.4e-12 47.9 0.2 9.5e-08 32.3 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG72529.1 - 1.7e-11 44.1 0.0 3.8e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG72529.1 - 5.9e-11 42.3 0.0 5.5e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72529.1 - 4.1e-07 29.8 0.0 0.036 13.9 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease DUF1758 PF05585.12 GBG72529.1 - 0.0024 17.6 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Retrotrans_gag PF03732.17 GBG72529.1 - 0.0032 17.7 0.1 0.013 15.8 0.1 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein HepII_C PF18675.1 GBG72529.1 - 0.18 11.9 0.0 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Heparinase II C-terminal domain rve PF00665.26 GBG72530.1 - 2.3e-11 43.9 0.1 5.5e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG72531.1 - 2.8e-30 104.3 0.0 5e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72531.1 - 1.1e-28 99.6 0.1 3.8e-28 97.8 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG72531.1 - 0.02 15.1 0.1 0.045 14.0 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Mcp5_PH PF12814.7 GBG72531.1 - 0.026 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Nse4_C PF08743.10 GBG72531.1 - 0.39 11.0 1.2 3.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Nse4 C-terminal RVT_1 PF00078.27 GBG72532.1 - 9.7e-35 120.1 0.1 1.5e-34 119.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exotox-A_cataly PF09009.10 GBG72532.1 - 0.036 13.8 0.2 0.072 12.8 0.2 1.4 1 0 0 1 1 1 0 Exotoxin A catalytic YabA PF06156.13 GBG72532.1 - 1.3 9.7 0.0 1.3 9.7 0.0 3.5 4 1 0 4 4 4 0 Initiation control protein YabA DUF5464 PF17552.2 GBG72532.1 - 1.3 9.3 6.3 3.3 8.0 6.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5464) Tom22 PF04281.13 GBG72532.1 - 1.9 8.3 11.0 0.051 13.4 0.7 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 LMBR1 PF04791.16 GBG72532.1 - 4.5 6.1 7.3 3.5 6.4 0.0 2.3 2 0 0 2 2 2 0 LMBR1-like membrane protein RT_RNaseH PF17917.1 GBG72533.1 - 2.4e-19 69.5 0.0 4.3e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72533.1 - 1.8e-17 63.2 0.0 3.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72533.1 - 5.3e-05 23.2 1.6 7.2e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG72533.1 - 0.00021 20.9 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72534.1 - 4.2e-28 97.3 0.0 1.2e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72534.1 - 5.4e-28 97.4 0.0 1.5e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72534.1 - 9.4e-23 80.9 0.0 3.1e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72534.1 - 2.2e-15 56.5 0.1 7.1e-15 54.9 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72534.1 - 1.4e-07 31.7 0.0 5.1e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG72534.1 - 1.8e-07 31.7 0.0 4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72534.1 - 2e-06 28.2 0.0 5.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG72534.1 - 2.1e-05 24.3 0.0 4.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72534.1 - 0.00084 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG72534.1 - 0.0017 18.6 5.3 0.0088 16.3 0.0 4.3 4 0 0 4 4 4 1 Retrotransposon gag protein Chromo PF00385.24 GBG72534.1 - 0.0025 17.7 0.0 0.0061 16.5 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG72534.1 - 0.088 13.0 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger NPV_P10 PF05531.12 GBG72534.1 - 0.13 12.7 0.1 1.5 9.3 0.2 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG72535.1 - 1.5e-24 86.8 0.1 4.7e-24 85.1 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72535.1 - 1.9e-20 73.1 0.0 4.6e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72535.1 - 3.9e-20 71.8 0.0 1e-19 70.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72535.1 - 8.4e-19 67.4 0.4 2.1e-18 66.2 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG72535.1 - 0.01 16.1 0.1 0.068 13.4 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Integrin_b_cyt PF08725.11 GBG72535.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain SlyX PF04102.12 GBG72535.1 - 2.5 8.8 11.2 0.13 12.9 1.4 3.6 3 1 1 4 4 4 0 SlyX TolA_bind_tri PF16331.5 GBG72535.1 - 3.9 7.6 8.0 2 8.6 4.1 2.6 2 1 1 3 3 3 0 TolA binding protein trimerisation AT_hook PF02178.19 GBG72536.1 - 0.86 9.7 14.1 0.94 9.6 2.8 3.2 2 0 0 2 2 2 0 AT hook motif PAT1 PF09770.9 GBG72536.1 - 0.95 7.7 30.8 1.2 7.3 30.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.6 GBG72536.1 - 1.3 9.6 13.9 1.8 9.1 13.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Ufd2P_core PF10408.9 GBG72537.1 - 4.5e-140 468.2 0.5 5.9e-140 467.8 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 GBG72537.1 - 8.2e-31 106.0 0.7 2.5e-30 104.5 0.7 1.9 1 0 0 1 1 1 1 U-box domain rve PF00665.26 GBG72537.1 - 5.2e-09 36.3 0.1 1.7e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DUF724 PF05266.14 GBG72537.1 - 0.072 12.9 1.4 0.17 11.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF659 PF04937.15 GBG72539.1 - 3.9e-14 52.8 0.0 8.2e-13 48.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) Ufd2P_core PF10408.9 GBG72540.1 - 2.7e-48 165.1 0.0 4.2e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core DUF659 PF04937.15 GBG72540.1 - 8.5e-11 41.9 0.0 2e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG72540.1 - 0.0024 17.6 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG72541.1 - 2.9e-26 92.4 0.0 4.6e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72541.1 - 1.6e-15 57.0 0.0 3.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72541.1 - 1.3e-12 47.6 0.0 6e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG72541.1 - 1.6e-05 25.0 0.0 3.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG72541.1 - 0.00059 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG72542.1 - 2e-23 82.2 17.6 0.00039 21.2 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ATG16 PF08614.11 GBG72542.1 - 1.5e-18 67.8 15.2 1.5e-18 67.8 15.2 2.6 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) ANAPC4_WD40 PF12894.7 GBG72542.1 - 2.8e-06 27.5 3.5 0.0012 19.1 0.0 4.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Baculo_PEP_C PF04513.12 GBG72542.1 - 0.16 12.0 1.8 0.42 10.7 1.8 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus EGF_MSP1_1 PF12946.7 GBG72542.1 - 1.1 9.3 5.1 37 4.5 3.6 2.7 2 0 0 2 2 2 0 MSP1 EGF domain 1 FH2 PF02181.23 GBG72542.1 - 9.2 5.3 13.8 12 4.9 3.9 2.4 1 1 1 2 2 2 0 Formin Homology 2 Domain gag-asp_proteas PF13975.6 GBG72544.1 - 1.2e-07 32.1 0.1 7.5e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72544.1 - 0.00012 22.6 0.0 0.00048 20.7 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG72544.1 - 0.004 17.0 0.1 0.01 15.6 0.1 1.6 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 GBG72544.1 - 0.018 15.1 0.7 0.039 14.0 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 GBG72544.1 - 0.033 13.0 2.3 0.087 11.6 2.3 1.6 1 0 0 1 1 1 0 Presenilin RVP PF00077.20 GBG72544.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GBG72544.1 - 0.25 11.2 1.1 0.49 10.3 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG72547.1 - 2.8e-22 78.6 0.0 5.2e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72547.1 - 2.5e-20 72.7 0.0 5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG72547.1 - 0.019 15.5 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG72547.1 - 0.02 15.2 0.0 0.068 13.5 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72547.1 - 0.043 14.5 0.1 0.11 13.2 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease Mer2 PF09074.10 GBG72547.1 - 0.062 13.1 0.5 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 Mer2 Retrotrans_gag PF03732.17 GBG72547.1 - 0.13 12.5 0.6 0.39 11.0 0.6 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG72547.1 - 0.4 10.5 2.1 0.77 9.6 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG72548.1 - 4.3e-24 85.3 0.1 1.6e-22 80.2 0.1 2.7 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72548.1 - 4.8e-20 71.5 0.0 1.1e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72548.1 - 7.2e-09 35.9 0.0 1.9e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG72548.1 - 6.6e-05 22.8 2.8 0.00019 21.3 2.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG72548.1 - 0.18 11.5 1.2 0.51 10.1 1.2 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger MAT1 PF06391.13 GBG72548.1 - 3.5 7.4 20.5 6.8 6.5 20.5 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 RR_TM4-6 PF06459.12 GBG72549.1 - 0.0085 15.9 1.5 0.0099 15.7 1.5 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 GBG72549.1 - 0.042 12.6 0.3 0.048 12.4 0.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CUE PF02845.16 GBG72549.1 - 0.069 12.9 0.1 0.18 11.6 0.0 1.7 1 1 1 2 2 2 0 CUE domain PRTP PF01366.18 GBG72549.1 - 1 7.3 3.1 1.3 6.9 3.1 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RVT_1 PF00078.27 GBG72550.1 - 3e-27 95.6 0.1 9.5e-27 93.9 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_polI_A34 PF08208.11 GBG72550.1 - 0.00092 19.4 12.6 0.0015 18.7 12.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 SDA1 PF05285.12 GBG72550.1 - 0.0076 15.7 23.0 0.011 15.2 23.0 1.1 1 0 0 1 1 1 1 SDA1 SAPS PF04499.15 GBG72550.1 - 0.015 14.1 1.0 0.02 13.7 1.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 GBG72550.1 - 0.017 14.5 18.8 0.023 14.1 18.8 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG72550.1 - 0.079 11.2 25.2 0.11 10.7 25.2 1.1 1 0 0 1 1 1 0 Nop14-like family Eapp_C PF10238.9 GBG72550.1 - 0.14 12.2 6.9 0.23 11.5 6.9 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein DDHD PF02862.17 GBG72550.1 - 0.17 12.1 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 DDHD domain Mpp10 PF04006.12 GBG72550.1 - 0.55 8.6 26.0 0.78 8.1 26.0 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 GBG72550.1 - 0.58 8.4 18.2 0.83 7.9 18.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Drc1-Sld2 PF11719.8 GBG72550.1 - 0.94 9.0 11.9 1.5 8.3 11.9 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein NPR3 PF03666.13 GBG72550.1 - 1.1 8.0 8.4 1.6 7.5 8.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 GBG72550.1 - 1.3 8.4 11.6 1.9 7.9 11.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 GBG72550.1 - 2.4 6.8 10.3 3.5 6.3 10.3 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 GBG72550.1 - 2.4 8.6 10.7 4 7.9 10.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Spore_coat_CotO PF14153.6 GBG72550.1 - 4.2 7.3 19.3 6.6 6.6 19.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Na_trans_assoc PF06512.13 GBG72550.1 - 5.7 7.2 17.5 9.2 6.5 17.5 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Trypan_PARP PF05887.11 GBG72550.1 - 7.4 6.5 29.0 14 5.6 29.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RT_RNaseH_2 PF17919.1 GBG72552.1 - 3.8e-28 97.5 0.1 7.1e-28 96.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72552.1 - 1.6e-24 86.7 0.0 2.6e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72552.1 - 2.2e-24 85.8 0.1 3.6e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72552.1 - 2.5e-07 30.7 0.0 4.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG72553.1 - 2.5e-15 56.3 0.0 5.6e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72553.1 - 2.2e-06 27.9 0.0 4.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72553.1 - 0.038 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72554.1 - 6.6e-14 51.8 0.0 1.8e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72554.1 - 9.6e-06 25.8 0.0 2.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG72554.1 - 0.0097 15.4 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72555.1 - 1.6e-30 105.0 0.2 1.3e-29 102.1 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72555.1 - 3.1e-29 101.3 0.0 1.1e-28 99.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG72555.1 - 0.022 15.0 0.0 0.52 10.6 0.0 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein Pan_kinase PF03309.14 GBG72555.1 - 0.034 13.9 1.5 0.07 12.9 1.5 1.5 1 0 0 1 1 1 0 Type III pantothenate kinase WTX PF09422.10 GBG72555.1 - 0.16 11.0 3.9 0.24 10.4 3.9 1.2 1 0 0 1 1 1 0 WTX protein Phage_GPO PF05929.11 GBG72555.1 - 0.74 9.4 0.0 0.74 9.4 0.0 3.5 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG72556.1 - 5.3e-26 91.5 0.0 9.4e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72556.1 - 1.8e-21 76.0 0.0 6e-21 74.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72556.1 - 2e-18 66.2 0.1 2e-18 66.2 0.1 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG72556.1 - 3e-13 50.0 0.0 8.2e-11 42.1 0.0 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72556.1 - 7.3e-09 35.8 0.0 2.5e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG72556.1 - 0.0035 17.6 0.1 0.023 14.9 0.1 2.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG72556.1 - 0.15 12.3 0.6 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger RVP_2 PF08284.11 GBG72557.1 - 2.7e-08 33.7 0.0 5.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72557.1 - 2.1e-07 31.5 0.0 6.4e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72557.1 - 5.4e-05 23.7 0.0 0.0002 21.8 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Abhydrolase_1 PF00561.20 GBG72557.1 - 0.00012 21.8 0.0 0.00043 20.0 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Asp_protease PF09668.10 GBG72557.1 - 0.0042 16.9 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Hydrolase_4 PF12146.8 GBG72557.1 - 0.053 12.8 1.0 8 5.6 0.0 3.1 4 0 0 4 4 4 0 Serine aminopeptidase, S33 rve PF00665.26 GBG72559.1 - 8.7e-11 42.1 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG72559.1 - 0.0011 18.7 0.0 0.0034 17.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Pectinesterase PF01095.19 GBG72560.1 - 1.2e-64 217.9 4.3 1.4e-64 217.7 4.3 1.0 1 0 0 1 1 1 1 Pectinesterase Integrase_H2C2 PF17921.1 GBG72561.1 - 8.9e-17 60.9 0.4 2.3e-16 59.7 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG72561.1 - 5.4e-06 27.0 0.0 0.00011 22.8 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG72561.1 - 7.2e-06 26.2 0.1 0.18 12.1 0.0 2.6 2 0 0 2 2 2 2 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG72561.1 - 1.4e-05 25.6 0.0 7.6e-05 23.2 0.0 2.3 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG72561.1 - 0.00069 19.6 14.0 0.023 14.8 2.2 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-H2C2 PF09337.10 GBG72561.1 - 0.15 12.3 0.8 0.4 10.9 0.3 2.1 2 0 0 2 2 2 0 H2C2 zinc finger CAP_N PF01213.19 GBG72561.1 - 0.21 11.0 1.9 0.55 9.7 1.9 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RT_RNaseH_2 PF17919.1 GBG72562.1 - 1.7e-23 82.6 0.0 3.5e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72562.1 - 5.8e-22 78.0 0.0 1.4e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72562.1 - 1.5e-08 34.5 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72563.1 - 9.1e-15 54.5 0.1 1.6e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72563.1 - 2e-14 53.8 0.0 4.2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain CHASE3 PF05227.13 GBG72564.1 - 0.0051 16.7 0.6 0.033 14.1 0.3 2.0 1 1 1 2 2 2 1 CHASE3 domain RVT_1 PF00078.27 GBG72565.1 - 7.4e-32 110.7 0.1 1.1e-31 110.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72565.1 - 1.3e-28 99.0 0.0 2.3e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72565.1 - 3.2e-18 65.9 0.0 5.9e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Fic_N PF13784.6 GBG72565.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Fic/DOC family N-terminal RT_RNaseH_2 PF17919.1 GBG72566.1 - 1.7e-34 117.8 0.5 3.1e-34 117.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72566.1 - 8.2e-26 90.3 0.0 1.4e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72566.1 - 1.9e-05 24.7 0.0 4.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72566.1 - 0.00065 19.9 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG72567.1 - 6.3e-15 55.0 0.2 2.3e-14 53.2 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG72567.1 - 3.3e-05 24.0 0.0 5.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG72568.1 - 1.3e-27 96.8 0.0 8.3e-21 74.5 0.0 3.4 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIA PF03153.13 GBG72568.1 - 0.00059 20.0 16.1 0.00059 20.0 16.1 3.3 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit DEK_C PF08766.11 GBG72570.1 - 2.6e-07 30.5 0.1 0.036 14.0 0.0 2.5 2 0 0 2 2 2 2 DEK C terminal domain DUF573 PF04504.14 GBG72570.1 - 0.0034 18.0 0.1 8.7 7.1 0.1 3.1 4 0 0 4 4 4 2 Protein of unknown function, DUF573 DNA_pol_alpha_N PF12254.8 GBG72570.1 - 0.02 15.0 0.1 14 5.8 0.0 2.9 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal MADF_DNA_bdg PF10545.9 GBG72570.1 - 0.021 15.1 3.6 4.5 7.7 0.3 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Atu4866 PF11512.8 GBG72570.1 - 0.092 13.1 0.1 31 5.0 0.0 2.6 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 IL12p40_C PF10420.9 GBG72570.1 - 0.14 12.6 2.5 23 5.6 0.2 3.0 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus Erg28 PF03694.13 GBG72570.1 - 2.1 8.7 5.4 50 4.3 0.5 3.0 3 0 0 3 3 3 0 Erg28 like protein DUF659 PF04937.15 GBG72571.1 - 2.5e-25 89.1 0.0 4.8e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG72573.1 - 2.4e-34 118.8 0.6 2.9e-28 98.9 0.1 3.0 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72573.1 - 1.9e-19 69.5 0.0 2.4e-17 62.8 0.0 3.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72573.1 - 3.4e-17 62.7 0.1 2.1e-08 34.4 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG72573.1 - 7.8e-08 32.9 0.0 2.5e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72573.1 - 1.5e-07 31.9 0.0 8.3e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG72573.1 - 6e-06 26.1 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72573.1 - 0.00015 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG72573.1 - 0.00057 20.1 10.2 0.0038 17.5 0.0 4.4 3 1 2 5 5 5 2 Retrotransposon gag protein PKHD_C PF18331.1 GBG72573.1 - 0.014 15.4 0.3 0.22 11.6 0.1 2.8 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain HIP1_clath_bdg PF16515.5 GBG72573.1 - 0.039 14.6 5.7 0.042 14.5 3.1 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Senescence_reg PF04520.13 GBG72573.1 - 0.093 13.6 0.5 0.41 11.5 0.3 2.1 2 0 0 2 2 2 0 Senescence regulator NPV_P10 PF05531.12 GBG72573.1 - 1.2 9.6 2.7 1.7 9.2 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG72574.1 - 4.7e-11 42.6 0.0 8.2e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG72574.1 - 3.4e-07 30.7 1.3 1.7e-06 28.5 0.1 2.7 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72574.1 - 0.00023 21.8 0.1 0.00064 20.3 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG72574.1 - 0.00073 19.3 0.1 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG72574.1 - 0.039 13.6 0.3 0.083 12.6 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVP_2 PF08284.11 GBG72574.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG72574.1 - 0.071 13.2 2.3 0.14 12.3 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF484 PF04340.12 GBG72574.1 - 0.65 9.7 5.4 1.1 8.8 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF484 RT_RNaseH PF17917.1 GBG72575.1 - 1e-16 61.1 0.0 1.9e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72575.1 - 3.6e-15 55.8 0.5 2.6e-14 53.1 0.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG72575.1 - 2.2e-12 46.9 0.0 3.9e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72575.1 - 2.3e-09 37.5 0.0 5.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain ACT PF01842.25 GBG72576.1 - 0.00063 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 GBG72576.1 - 0.007 16.9 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain QWRF PF04484.12 GBG72576.1 - 3.2 7.4 7.1 6 6.5 7.1 1.4 1 0 0 1 1 1 0 QWRF family DUF3482 PF11981.8 GBG72576.1 - 9.6 5.5 7.1 14 5.0 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF659 PF04937.15 GBG72577.1 - 1.9e-18 66.8 0.1 3.6e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Methyltransf_16 PF10294.9 GBG72578.1 - 0.055 13.2 0.1 0.091 12.5 0.1 1.4 1 0 0 1 1 1 0 Lysine methyltransferase RT_RNaseH_2 PF17919.1 GBG72581.1 - 2.9e-27 94.6 0.1 5.4e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72581.1 - 4.3e-25 88.0 0.8 8.5e-25 87.1 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG72581.1 - 0.026 14.4 0.2 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC_3 PF13917.6 GBG72581.1 - 1.6 8.8 7.0 0.43 10.6 0.8 2.8 3 0 0 3 3 3 0 Zinc knuckle SIMPL PF04402.14 GBG72582.1 - 0.23 11.9 1.3 0.72 10.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF541) DUF659 PF04937.15 GBG72583.1 - 8.2e-30 103.7 0.0 1.4e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG72583.1 - 0.027 14.3 0.2 0.027 14.3 0.2 2.2 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Macoilin PF09726.9 GBG72583.1 - 5.5 5.4 14.3 8.2 4.9 14.3 1.2 1 0 0 1 1 1 0 Macoilin family RVP_2 PF08284.11 GBG72584.1 - 2.6e-06 27.2 0.0 7.8e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72584.1 - 2.8e-06 27.9 0.0 7.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72584.1 - 3.4e-06 27.5 0.0 1.6e-05 25.4 0.0 2.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG72584.1 - 0.00047 19.9 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Sec62 PF03839.16 GBG72584.1 - 0.22 11.0 1.2 0.38 10.2 1.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 PIEZO PF15917.5 GBG72584.1 - 0.87 9.0 9.4 0.13 11.7 5.5 1.5 2 0 0 2 2 2 0 Piezo HD_4 PF13328.6 GBG72585.1 - 7.3e-25 87.5 0.4 7.9e-25 87.4 0.4 1.0 1 0 0 1 1 1 1 HD domain HD PF01966.22 GBG72585.1 - 3.6e-06 27.2 0.0 5.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 HD domain RVT_1 PF00078.27 GBG72587.1 - 5.7e-25 88.1 0.1 9.7e-25 87.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72587.1 - 1.6e-16 60.1 0.2 3.3e-16 59.1 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG72587.1 - 3.8e-09 36.5 0.0 9.4e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72587.1 - 6.8e-06 26.3 0.1 0.053 13.8 0.0 2.9 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG72587.1 - 0.00048 20.3 0.6 0.0016 18.7 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein HD_4 PF13328.6 GBG72587.1 - 0.00086 19.1 0.0 0.0028 17.4 0.0 1.9 1 0 0 1 1 1 1 HD domain RVP_2 PF08284.11 GBG72587.1 - 0.00088 19.0 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG72589.1 - 7.5e-06 25.6 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 GBG72589.1 - 9.4 4.9 13.8 19 3.9 13.8 1.4 1 0 0 1 1 1 0 Presenilin CF222 PF15661.5 GBG72591.1 - 0.091 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 C6orf222, uncharacterised family RVT_1 PF00078.27 GBG72592.1 - 7e-27 94.4 0.0 3.5e-26 92.1 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIA PF03153.13 GBG72592.1 - 9.2e-16 58.9 3.0 9.2e-16 58.9 3.0 2.9 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Asp_protease_2 PF13650.6 GBG72592.1 - 1.1e-07 32.4 0.0 3e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72592.1 - 1.6e-06 28.6 0.0 4.6e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG72592.1 - 1.8e-06 27.7 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72592.1 - 0.00025 20.8 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG72592.1 - 0.00066 19.9 1.1 0.0047 17.2 0.0 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein CLZ PF16526.5 GBG72592.1 - 5.6 7.4 4.9 25 5.3 0.4 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RT_RNaseH_2 PF17919.1 GBG72593.1 - 1.8e-23 82.4 0.0 3.9e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72593.1 - 2.9e-21 75.7 0.0 1.2e-20 73.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72593.1 - 5.2e-20 71.9 0.0 1.2e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG72593.1 - 0.0064 15.7 1.6 0.95 8.5 0.4 2.8 2 1 1 3 3 3 1 Autophagy protein Apg17 Sigma54_CBD PF04963.13 GBG72593.1 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain AIP3 PF03915.13 GBG72593.1 - 0.16 11.0 0.3 0.28 10.2 0.3 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 RT_RNaseH PF17917.1 GBG72594.1 - 1e-53 180.0 0.9 6.2e-30 103.6 0.1 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72594.1 - 3e-50 168.4 0.9 1.8e-33 114.6 0.1 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72594.1 - 5.9e-36 124.1 0.3 9e-23 80.9 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIA PF03153.13 GBG72594.1 - 9.4e-27 95.1 0.2 9.4e-27 95.1 0.2 3.9 4 1 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit Integrase_H2C2 PF17921.1 GBG72594.1 - 4.3e-07 29.9 0.4 1.3e-06 28.4 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain SpvB PF03534.13 GBG72594.1 - 0.025 13.8 0.2 6.2 5.9 0.0 2.7 2 0 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein CENP-B_dimeris PF09026.10 GBG72594.1 - 9.9 6.6 8.7 5.8 7.4 2.3 3.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pannexin_like PF12534.8 GBG72595.1 - 1.4 8.0 2.7 1.5 7.8 0.0 1.9 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 RT_RNaseH_2 PF17919.1 GBG72596.1 - 1.7e-32 111.4 0.0 4.1e-32 110.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72596.1 - 1.2e-31 109.9 0.1 2e-31 109.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72596.1 - 3.2e-28 98.1 0.1 5.9e-28 97.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Tub PF01167.18 GBG72598.1 - 4.8e-90 301.5 0.0 6e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 Tub family F-box PF00646.33 GBG72598.1 - 2e-07 30.7 0.8 3e-07 30.1 0.1 1.7 2 0 0 2 2 2 1 F-box domain DUF3527 PF12043.8 GBG72598.1 - 0.016 14.8 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) F-box-like PF12937.7 GBG72598.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 F-box-like UQ_con PF00179.26 GBG72599.1 - 7e-38 129.4 0.0 9.5e-38 129.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mrr_N PF14338.6 GBG72601.1 - 0.17 12.0 0.6 3.1 8.0 0.0 2.7 2 1 1 3 3 3 0 Mrr N-terminal domain TRAF_BIRC3_bd PF16673.5 GBG72601.1 - 0.19 11.5 0.9 0.55 10.1 0.3 2.0 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain SlyX PF04102.12 GBG72601.1 - 0.28 11.8 2.9 49 4.6 0.0 3.9 4 0 0 4 4 4 0 SlyX DUF3629 PF12302.8 GBG72602.1 - 1.5 8.2 7.9 2.6 7.5 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) AAA_11 PF13086.6 GBG72602.1 - 5.2 6.8 9.9 5.7 6.6 9.9 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 GBG72603.1 - 1.3e-17 63.9 8.1 6.6e-05 23.6 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat TPR_14 PF13428.6 GBG72604.1 - 3.4e-19 67.9 14.6 0.0015 19.2 0.3 8.3 1 1 7 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 GBG72604.1 - 1.2e-15 57.8 7.1 4.8e-05 23.8 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG72604.1 - 6.2e-14 50.9 21.0 0.1 12.8 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 GBG72604.1 - 1.5e-12 47.0 2.3 0.0012 19.1 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GBG72604.1 - 1.4e-10 41.7 11.7 0.0022 18.6 0.0 5.0 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 GBG72604.1 - 6.6e-10 39.1 15.5 0.00019 21.7 0.1 6.3 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 GBG72604.1 - 1.4e-09 37.4 7.0 0.0095 16.1 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 GBG72604.1 - 4.9e-07 29.2 9.5 1.1e-06 28.1 9.2 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG72604.1 - 8.1e-05 22.4 15.1 0.0044 16.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG72604.1 - 0.00013 21.7 8.5 2.2 8.2 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat Suf PF05843.14 GBG72604.1 - 0.0015 18.6 0.1 0.03 14.3 0.0 2.6 1 1 2 3 3 3 1 Suppressor of forked protein (Suf) TPR_MalT PF17874.1 GBG72604.1 - 0.022 14.2 6.1 0.26 10.6 0.2 2.6 1 1 1 2 2 2 0 MalT-like TPR region Mad3_BUB1_I PF08311.12 GBG72604.1 - 0.029 14.3 7.4 3.5 7.6 0.1 5.4 6 2 0 7 7 7 0 Mad3/BUB1 homology region 1 TPR_11 PF13414.6 GBG72604.1 - 0.039 13.7 1.4 6 6.6 0.0 4.3 5 1 1 6 6 6 0 TPR repeat TPR_7 PF13176.6 GBG72604.1 - 0.065 13.3 1.0 0.94 9.7 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 GBG72604.1 - 0.098 13.3 10.6 0.23 12.2 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG72604.1 - 0.17 12.6 13.8 1.9 9.3 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG72604.1 - 0.27 11.4 12.1 27 5.0 0.0 5.4 3 1 1 6 6 5 0 Tetratricopeptide repeat HEM4 PF02602.15 GBG72605.1 - 7.8e-35 120.3 0.4 2.9e-34 118.5 0.4 1.8 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD CDC45 PF02724.14 GBG72606.1 - 0.83 7.9 2.6 0.92 7.7 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Arm PF00514.23 GBG72607.1 - 0.045 13.8 0.3 10 6.3 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Mito_fiss_reg PF05308.11 GBG72607.1 - 6.1 6.9 11.9 2.2 8.3 2.9 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator RVT_1 PF00078.27 GBG72608.1 - 1.2e-30 106.7 0.0 1.7e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72608.1 - 1.1e-19 70.3 0.4 3.9e-19 68.5 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG72608.1 - 2.8e-08 34.0 0.0 5.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72608.1 - 0.04 14.2 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF3563 PF12086.8 GBG72609.1 - 0.27 11.0 2.2 0.31 10.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) RVT_1 PF00078.27 GBG72610.1 - 2.6e-32 112.1 0.0 3.7e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCD48 PF15799.5 GBG72610.1 - 0.0054 15.1 3.1 0.0081 14.5 3.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 HALZ PF02183.18 GBG72610.1 - 0.11 12.8 1.1 0.26 11.5 1.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 GBG72610.1 - 0.75 10.3 5.9 0.29 11.6 2.8 1.9 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 GBG72610.1 - 2 8.6 9.1 2.2 8.4 2.7 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Roc PF08477.13 GBG72612.1 - 6e-07 29.7 0.0 3.1e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GBG72612.1 - 0.008 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 GBG72612.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Ras PF00071.22 GBG72612.1 - 0.09 12.4 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 Ras family COR PF16095.5 GBG72613.1 - 1.9e-08 34.3 0.0 7e-08 32.5 0.0 1.8 1 1 1 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 GBG72613.1 - 4.5e-08 33.3 0.0 2.7e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase EFhand_Ca_insen PF08726.10 GBG72613.1 - 0.0097 16.0 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 1 Ca2+ insensitive EF hand MMR_HSR1 PF01926.23 GBG72613.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.21 GBG72613.1 - 0.038 13.4 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Ras PF00071.22 GBG72613.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Ras family RVT_1 PF00078.27 GBG72615.1 - 0.01 15.3 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_12 PF13424.6 GBG72616.1 - 2.2e-30 104.8 17.9 1.1e-09 38.5 0.7 7.2 5 2 3 8 8 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 GBG72616.1 - 5.3e-23 80.2 15.6 4.5e-06 26.3 0.4 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat rve PF00665.26 GBG72616.1 - 1e-14 54.8 0.1 3.1e-14 53.2 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain TPR_2 PF07719.17 GBG72616.1 - 2.9e-11 42.6 20.6 0.002 18.1 0.0 7.5 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG72616.1 - 7.6e-09 35.4 6.6 1.5e-06 27.8 6.7 5.0 4 2 1 5 5 5 2 MalT-like TPR region TPR_1 PF00515.28 GBG72616.1 - 7.7e-08 31.8 11.4 0.045 13.6 0.3 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG72616.1 - 9.4e-07 28.6 10.1 0.14 12.4 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG72616.1 - 8.3e-06 25.5 15.2 1.1 9.5 0.2 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG72616.1 - 0.082 13.6 6.8 30 5.5 0.1 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG72616.1 - 0.93 10.5 0.0 0.93 10.5 0.0 8.0 7 1 1 8 8 6 0 Tetratricopeptide repeat Prefoldin PF02996.17 GBG72616.1 - 7.1 6.6 0.0 7.1 6.6 0.0 4.9 5 1 0 5 5 5 0 Prefoldin subunit Adaptin_binding PF10199.9 GBG72617.1 - 0.16 12.6 4.4 0.88 10.2 5.5 1.7 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 COMP PF11598.8 GBG72617.1 - 0.16 12.4 0.7 0.37 11.3 0.7 1.6 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Retrotrans_gag PF03732.17 GBG72618.1 - 4.8e-05 23.6 2.3 0.0017 18.6 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein SPACA9 PF15120.6 GBG72618.1 - 0.1 12.4 2.5 0.41 10.4 1.4 2.3 2 1 1 3 3 3 0 Sperm acrosome-associated protein 9 Syntaxin-6_N PF09177.11 GBG72618.1 - 0.11 13.1 1.6 3.4 8.3 0.3 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlxA PF14282.6 GBG72618.1 - 3.4 7.7 23.1 2.5 8.1 1.0 3.9 3 1 0 3 3 3 0 FlxA-like protein LMBR1 PF04791.16 GBG72618.1 - 3.8 6.3 5.4 6 5.6 5.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein NPV_P10 PF05531.12 GBG72618.1 - 6 7.4 6.4 3.5 8.2 0.3 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 GBG72619.1 - 0.022 14.7 2.5 0.037 14.0 2.5 1.4 1 0 0 1 1 1 0 FlxA-like protein Enkurin PF13864.6 GBG72619.1 - 0.027 14.9 2.6 0.041 14.3 2.6 1.4 1 1 0 1 1 1 0 Calmodulin-binding Myb_DNA-bind_4 PF13837.6 GBG72622.1 - 4.3e-10 39.8 2.5 1.2e-09 38.4 0.3 2.7 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72622.1 - 0.033 14.5 2.0 0.078 13.3 0.4 2.4 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG72622.1 - 0.93 9.6 5.9 0.15 12.1 1.2 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DEAD PF00270.29 GBG72623.1 - 1e-15 57.9 0.1 1.5e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase YL1_C PF08265.11 GBG72623.1 - 8.3e-12 44.7 2.5 1.3e-11 44.0 2.5 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CDC45 PF02724.14 GBG72623.1 - 0.073 11.4 2.1 0.11 10.8 2.1 1.3 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG72624.1 - 8.4e-30 102.8 0.0 1.7e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72624.1 - 3.2e-28 98.1 0.1 6.2e-28 97.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72624.1 - 3.2e-18 65.6 0.2 6.5e-18 64.6 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72624.1 - 5.3e-15 55.7 0.0 1.2e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72624.1 - 0.00099 19.3 0.0 0.0031 17.7 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG72624.1 - 0.0039 16.9 0.4 0.02 14.6 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) Rab3-GTPase_cat PF13890.6 GBG72624.1 - 0.056 13.1 0.2 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit SLM4 PF16818.5 GBG72626.1 - 0.16 12.0 0.7 0.32 11.0 0.7 1.5 1 0 0 1 1 1 0 Protein SLM4 Ribosomal_L6e PF01159.19 GBG72626.1 - 0.2 12.2 0.6 13 6.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L6e SUIM_assoc PF16619.5 GBG72626.1 - 0.35 11.0 6.7 2.4 8.3 0.1 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Mito_carr PF00153.27 GBG72627.1 - 2.1e-63 210.3 0.1 9.9e-22 76.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.21 GBG72627.1 - 0.64 8.9 2.4 1.1 8.1 2.4 1.3 1 0 0 1 1 1 0 Amidase PH_2 PF08458.10 GBG72628.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Ish1 PF10281.9 GBG72628.1 - 0.2 12.0 1.6 0.31 11.4 0.1 2.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein GST_N_3 PF13417.6 GBG72629.1 - 2.6e-08 34.2 0.0 6.9e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GBG72629.1 - 2.9e-08 33.9 0.0 5.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GBG72629.1 - 2.2e-06 27.6 0.0 3.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GBG72629.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GBG72629.1 - 9.4e-05 22.6 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 GBG72629.1 - 0.0036 18.0 0.0 0.013 16.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 GBG72629.1 - 0.031 14.5 0.0 0.081 13.2 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain LEA_5 PF00477.17 GBG72630.1 - 4.2e-15 56.1 2.1 5.4e-15 55.8 2.1 1.2 1 0 0 1 1 1 1 Small hydrophilic plant seed protein Histone PF00125.24 GBG72631.1 - 9.9e-22 77.7 3.9 1e-21 77.6 0.3 2.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG72631.1 - 0.14 12.6 0.7 0.46 10.9 0.2 2.1 2 0 0 2 2 2 0 CENP-S protein zf-U11-48K PF05253.12 GBG72631.1 - 0.18 11.7 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger PTPRCAP PF15713.5 GBG72632.1 - 0.0022 18.3 2.5 0.0022 18.3 2.5 2.2 2 0 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated RXLR PF16810.5 GBG72632.1 - 1.6 9.1 5.1 12 6.3 0.1 2.3 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Integrase_H2C2 PF17921.1 GBG72633.1 - 3.5e-15 55.8 0.1 7.8e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG72633.1 - 0.0095 16.1 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF1844 PF08899.11 GBG72633.1 - 0.16 12.2 0.0 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) GIY-YIG PF01541.24 GBG72634.1 - 1.6e-05 25.0 0.7 7.1e-05 23.0 0.5 2.4 2 0 0 2 2 2 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG72634.1 - 0.0011 18.9 1.6 0.0043 17.1 1.6 2.1 1 0 0 1 1 1 1 Zinc knuckle TPT PF03151.16 GBG72635.1 - 1.7e-11 44.0 11.5 2.4e-11 43.5 11.5 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF5353 PF17304.2 GBG72635.1 - 0.066 13.0 0.1 0.066 13.0 0.1 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5353) DnaJ PF00226.31 GBG72636.1 - 2.1e-19 69.4 0.0 3.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 GBG72636.1 - 2.9e-12 46.9 2.3 2.9e-12 46.9 2.3 2.6 3 0 0 3 3 3 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 GBG72636.1 - 8.5e-05 23.2 4.6 8.5e-05 23.2 4.6 3.1 3 1 0 3 3 3 1 4Fe-4S single cluster domain Fer4_10 PF13237.6 GBG72636.1 - 0.027 14.6 1.2 0.072 13.2 1.2 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain SSI PF00720.17 GBG72636.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Subtilisin inhibitor-like Fer4_21 PF14697.6 GBG72636.1 - 0.14 12.3 3.5 0.37 11.0 3.5 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 GBG72636.1 - 0.36 10.7 5.7 0.56 10.1 0.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain AFP PF02420.15 GBG72636.1 - 3.8 8.2 5.7 12 6.7 5.7 1.9 1 0 0 1 1 1 0 Insect antifreeze protein repeat YTH PF04146.15 GBG72638.1 - 1.7e-37 129.0 0.3 1.7e-37 129.0 0.3 3.6 3 0 0 3 3 3 1 YT521-B-like domain RE_AspBHI_N PF18062.1 GBG72638.1 - 7.2e-05 22.4 0.1 0.00023 20.8 0.0 1.8 2 0 0 2 2 2 1 Restriction endonuclease AspBHI N-terminal PrmA PF06325.13 GBG72638.1 - 0.99 8.7 3.0 1.6 8.1 3.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RT_RNaseH_2 PF17919.1 GBG72639.1 - 1.5e-26 92.3 0.0 2.5e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72639.1 - 3.9e-24 84.9 0.0 6.7e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72639.1 - 1.3e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG72639.1 - 0.31 9.2 9.2 0.42 8.8 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG72639.1 - 0.52 8.5 8.8 0.75 8.0 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG72639.1 - 0.63 9.4 9.9 0.88 8.9 9.9 1.1 1 0 0 1 1 1 0 SDA1 RRP36 PF06102.12 GBG72641.1 - 1.9e-42 145.0 20.4 2.2e-42 144.8 20.4 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 Lipoprotein_18 PF06804.11 GBG72643.1 - 0.44 9.5 4.7 0.73 8.8 4.7 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein rve PF00665.26 GBG72646.1 - 0.00013 22.1 0.0 0.00031 20.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG72646.1 - 0.1 12.5 0.2 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain TPR_12 PF13424.6 GBG72647.1 - 4.4e-16 58.9 0.6 5.3e-09 36.2 0.0 3.6 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG72647.1 - 7e-11 41.4 1.1 0.0047 16.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG72647.1 - 1.5e-08 34.1 0.5 0.11 12.4 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG72647.1 - 4.5e-07 29.6 1.9 0.17 12.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG72647.1 - 1.8e-05 24.4 0.0 0.75 10.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG72647.1 - 2.1e-05 24.2 2.8 0.013 15.4 0.0 4.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG72647.1 - 0.0016 17.9 0.0 0.33 10.3 0.0 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 GBG72647.1 - 0.002 18.8 0.0 12 7.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG72647.1 - 0.013 15.8 0.2 1.1 9.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GBG72647.1 - 0.017 14.8 0.2 7.6 6.3 0.0 3.3 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 GBG72647.1 - 0.16 12.7 1.2 8.1 7.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat APH PF01636.23 GBG72648.1 - 2.5e-16 60.4 0.0 3.8e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GBG72648.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 GBG72648.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase EcKinase PF02958.20 GBG72648.1 - 0.14 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase NPA PF16469.5 GBG72650.1 - 0.036 14.7 1.2 0.088 13.4 0.4 2.1 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 DivIC PF04977.15 GBG72650.1 - 0.85 9.4 3.5 1.5 8.6 1.2 2.4 1 1 1 2 2 2 0 Septum formation initiator ELMO_CED12 PF04727.13 GBG72651.1 - 3.2e-28 99.0 0.0 5.4e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family YL1 PF05764.13 GBG72651.1 - 0.08 13.0 15.3 0.12 12.4 15.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein BSP_II PF05432.11 GBG72651.1 - 0.083 12.6 16.7 0.13 11.9 16.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) GREB1 PF15782.5 GBG72651.1 - 0.48 7.5 1.5 0.56 7.3 1.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF755 PF05501.11 GBG72651.1 - 0.49 10.7 13.7 2.4 8.5 13.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Macoilin PF09726.9 GBG72651.1 - 1.8 7.0 8.2 2.3 6.6 8.2 1.1 1 0 0 1 1 1 0 Macoilin family RF-1 PF00472.20 GBG72652.1 - 0.043 13.7 7.9 0.076 13.0 7.9 1.4 1 0 0 1 1 1 0 RF-1 domain CDC45 PF02724.14 GBG72652.1 - 0.19 10.0 8.7 0.23 9.7 8.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 GBG72652.1 - 0.83 9.0 5.3 1.1 8.5 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ARF7EP_C PF14949.6 GBG72652.1 - 0.88 10.2 8.8 0.72 10.5 7.0 1.7 1 1 0 1 1 1 0 ARF7 effector protein C-terminus Presenilin PF01080.17 GBG72652.1 - 1.2 7.9 8.2 1.4 7.6 8.2 1.1 1 0 0 1 1 1 0 Presenilin Myc_N PF01056.18 GBG72652.1 - 1.2 8.9 7.8 1.6 8.5 7.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF4199 PF13858.6 GBG72652.1 - 7.7 6.9 5.4 11 6.4 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) FAM176 PF14851.6 GBG72652.1 - 7.8 6.2 10.2 12 5.6 10.2 1.3 1 0 0 1 1 1 0 FAM176 family Hid1 PF12722.7 GBG72652.1 - 8.1 4.4 5.7 9.7 4.2 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DEK_C PF08766.11 GBG72653.1 - 0.0031 17.4 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain PLD_C PF12357.8 GBG72654.1 - 1.4e-24 85.8 0.0 2.9e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Phospholipase D C terminal C2 PF00168.30 GBG72654.1 - 9.1e-24 83.7 0.0 2.4e-23 82.4 0.0 1.8 2 0 0 2 2 2 1 C2 domain PLDc PF00614.22 GBG72654.1 - 3.2e-18 65.1 0.1 1.4e-07 31.4 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG72654.1 - 2.6e-09 37.0 0.0 3.6e-06 26.9 0.0 3.1 3 0 0 3 3 3 2 PLD-like domain PTS_EIIB PF00367.20 GBG72654.1 - 0.092 12.3 0.1 0.4 10.2 0.1 2.0 2 0 0 2 2 2 0 phosphotransferase system, EIIB MqsR_toxin PF15723.5 GBG72654.1 - 0.95 9.9 5.0 0.4 11.1 0.6 2.6 3 0 0 3 3 3 0 Motility quorum-sensing regulator, toxin of MqsA RT_RNaseH PF17917.1 GBG72656.1 - 9.5e-30 103.0 0.1 2.3e-29 101.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72656.1 - 7.3e-29 99.8 0.0 1.5e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72656.1 - 4.4e-27 95.0 0.0 1.3e-26 93.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLD_C PF12357.8 GBG72656.1 - 2.2e-24 85.2 0.0 6.8e-23 80.4 0.0 2.7 2 0 0 2 2 2 1 Phospholipase D C terminal C2 PF00168.30 GBG72656.1 - 7.8e-21 74.3 0.0 2.6e-19 69.4 0.1 2.6 2 0 0 2 2 2 1 C2 domain PLDc PF00614.22 GBG72656.1 - 5.8e-16 57.9 0.1 1.7e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG72656.1 - 1.9e-08 34.3 0.0 2.9e-06 27.2 0.0 3.3 2 1 0 2 2 2 1 PLD-like domain MqsR_toxin PF15723.5 GBG72656.1 - 0.037 14.4 0.3 0.14 12.5 0.3 2.0 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA Helo_like_N PF17111.5 GBG72656.1 - 0.2 11.0 4.5 0.15 11.4 2.2 1.9 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Phage_GPO PF05929.11 GBG72656.1 - 0.33 10.5 3.7 0.37 10.4 0.1 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH PF17917.1 GBG72657.1 - 9.4e-30 103.0 0.1 2.3e-29 101.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72657.1 - 7.2e-29 99.8 0.0 1.5e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72657.1 - 4.4e-27 95.0 0.0 1.3e-26 93.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLD_C PF12357.8 GBG72657.1 - 2.1e-24 85.2 0.0 6.7e-23 80.4 0.0 2.7 2 0 0 2 2 2 1 Phospholipase D C terminal C2 PF00168.30 GBG72657.1 - 7.7e-21 74.3 0.0 2.6e-19 69.4 0.1 2.6 2 0 0 2 2 2 1 C2 domain PLDc PF00614.22 GBG72657.1 - 5.7e-16 58.0 0.1 1.7e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG72657.1 - 1.9e-08 34.3 0.0 2.8e-06 27.2 0.0 3.3 2 1 0 2 2 2 1 PLD-like domain MqsR_toxin PF15723.5 GBG72657.1 - 0.036 14.4 0.3 0.14 12.5 0.3 2.0 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA Helo_like_N PF17111.5 GBG72657.1 - 0.19 11.0 4.5 0.15 11.4 2.2 1.9 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Phage_GPO PF05929.11 GBG72657.1 - 0.33 10.5 3.7 0.36 10.4 0.1 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase C2 PF00168.30 GBG72658.1 - 1.2e-21 76.9 0.0 4e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 C2 domain PLD_C PF12357.8 GBG72658.1 - 1.5e-17 63.2 0.0 3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.22 GBG72658.1 - 8.6e-15 54.2 0.1 8.6e-07 28.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG72658.1 - 8.1e-10 38.7 0.0 2.3e-06 27.5 0.0 3.2 3 0 0 3 3 3 2 PLD-like domain MqsR_toxin PF15723.5 GBG72658.1 - 0.023 15.0 0.1 0.06 13.7 0.1 1.6 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA MFAP1 PF06991.11 GBG72659.1 - 1.8e-72 243.7 23.5 1.8e-72 243.7 23.5 2.2 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing DUF2510 PF10708.9 GBG72661.1 - 0.0016 18.1 0.1 0.94 9.3 0.0 3.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2510) PQQ_3 PF13570.6 GBG72662.1 - 0.00076 19.9 0.5 1.2e+02 3.3 0.0 6.2 5 0 0 5 5 5 0 PQQ-like domain DUF2510 PF10708.9 GBG72662.1 - 0.0019 17.9 0.1 0.93 9.3 0.0 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2510) PSII_BNR PF14870.6 GBG72662.1 - 0.013 14.8 2.5 15 4.7 0.3 4.2 3 1 0 3 3 3 0 Photosynthesis system II assembly factor YCF48 Integrase_H2C2 PF17921.1 GBG72663.1 - 2.1e-19 69.3 0.4 1.2e-18 67.0 0.2 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG72663.1 - 1.6e-13 50.8 0.0 3.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72663.1 - 3.4e-09 36.6 0.0 7.8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72663.1 - 8.4e-09 35.7 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72663.1 - 0.048 13.9 0.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 H2C2 zinc finger Chromo PF00385.24 GBG72663.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Dynactin_p62 PF05502.13 GBG72664.1 - 2.1e-05 23.5 45.2 0.0001 21.3 1.5 3.7 2 1 0 2 2 2 2 Dynactin p62 family Arm PF00514.23 GBG72664.1 - 0.012 15.7 0.9 0.079 13.0 0.1 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Myb_DNA-bind_4 PF13837.6 GBG72665.1 - 1.4e-08 34.9 1.2 2.6e-08 34.2 1.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG72665.1 - 0.0072 16.5 0.2 0.021 15.0 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Vps62 PF06101.11 GBG72666.1 - 0.00015 20.3 0.2 0.00022 19.7 0.2 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 SAPS PF04499.15 GBG72667.1 - 6e-55 186.9 1.6 7.1e-34 117.4 0.2 2.6 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein SAPS PF04499.15 GBG72668.1 - 2.2e-55 188.4 0.0 7.2e-34 117.4 0.2 2.6 1 1 1 2 2 2 2 SIT4 phosphatase-associated protein RT_RNaseH_2 PF17919.1 GBG72669.1 - 6.1e-14 51.9 0.0 1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72669.1 - 6.2e-05 23.2 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72669.1 - 0.0071 15.9 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG72669.1 - 0.05 11.9 9.9 0.059 11.7 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.11 GBG72669.1 - 0.91 8.9 8.0 1.2 8.5 8.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nop14 PF04147.12 GBG72669.1 - 3.6 5.7 24.2 4.5 5.4 24.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG72669.1 - 4.3 6.7 24.4 5.6 6.3 24.4 1.1 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 GBG72669.1 - 5.1 7.0 35.2 7.7 6.5 35.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) OST-HTH PF12872.7 GBG72670.1 - 1.7e-12 47.0 0.1 2.9e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain zf-C3HC4_2 PF13923.6 GBG72670.1 - 1.1e-10 41.2 10.8 3e-10 39.8 10.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG72670.1 - 1.3e-09 37.8 11.4 3.2e-09 36.5 11.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG72670.1 - 1.3e-09 38.1 12.1 3.2e-09 36.8 12.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GBG72670.1 - 2.1e-09 37.6 10.1 4.8e-09 36.4 10.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GBG72670.1 - 2.8e-09 36.7 8.5 7.1e-09 35.4 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG72670.1 - 3e-09 36.8 4.4 3e-09 36.8 4.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG72670.1 - 1.7e-06 27.8 9.1 5e-06 26.4 9.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain RRM_1 PF00076.22 GBG72670.1 - 2.6e-06 27.1 0.0 5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 GBG72670.1 - 1.8e-05 24.6 6.4 4.5e-05 23.4 6.4 1.7 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 GBG72670.1 - 4.7e-05 24.0 0.3 4.7e-05 24.0 0.3 3.7 3 0 0 3 3 2 1 Torus domain zf-Nse PF11789.8 GBG72670.1 - 6.2e-05 22.7 6.9 0.00017 21.3 6.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCCH PF00642.24 GBG72670.1 - 0.00011 22.0 5.4 0.00011 22.0 5.4 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-rbx1 PF12678.7 GBG72670.1 - 0.00051 20.3 5.3 0.00051 20.3 5.3 2.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GBG72670.1 - 0.00074 19.3 9.2 0.0054 16.6 9.5 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 GBG72670.1 - 0.0017 18.1 5.6 0.0036 17.1 5.6 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-RING_6 PF14835.6 GBG72670.1 - 0.0056 16.5 4.6 0.014 15.2 4.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 GBG72670.1 - 0.0065 16.6 7.5 0.017 15.2 7.5 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 GBG72670.1 - 0.28 11.0 9.2 1.1 9.2 9.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 GBG72670.1 - 0.49 10.9 4.4 12 6.4 0.3 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-P11 PF03854.14 GBG72670.1 - 1.3 8.7 4.0 3.9 7.2 4.0 1.8 1 0 0 1 1 1 0 P-11 zinc finger Presenilin PF01080.17 GBG72670.1 - 2.7 6.7 26.1 0.95 8.2 12.3 2.4 2 0 0 2 2 2 0 Presenilin DUF4746 PF15928.5 GBG72670.1 - 6.4 6.1 13.8 4.5 6.6 8.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) zf-CCHC PF00098.23 GBG72672.1 - 2.8e-52 172.6 92.4 4.2e-07 29.7 1.6 10.1 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_2 PF13696.6 GBG72672.1 - 3e-16 58.9 100.1 7.9e-05 22.4 2.1 10.2 10 0 0 10 10 10 9 Zinc knuckle zf-CCHC_4 PF14392.6 GBG72672.1 - 2e-12 46.7 73.2 0.041 13.6 0.9 10.1 10 0 0 10 10 10 9 Zinc knuckle zf-CCHC_3 PF13917.6 GBG72672.1 - 2.6e-05 24.1 71.4 0.062 13.3 0.7 10.0 6 1 4 10 10 10 9 Zinc knuckle zf-C2H2_10 PF16588.5 GBG72672.1 - 0.00086 19.0 2.2 0.00086 19.0 2.2 10.2 9 1 1 10 10 10 5 C2H2 zinc-finger zf-CCHC_6 PF15288.6 GBG72672.1 - 0.04 13.8 77.4 0.92 9.4 0.2 9.2 8 1 1 9 9 9 0 Zinc knuckle TRAP_alpha PF03896.16 GBG72673.1 - 2.3e-32 112.4 0.0 2.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Peptidase_S49_N PF08496.10 GBG72673.1 - 0.011 15.8 1.0 0.015 15.3 1.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal R_equi_Vir PF05526.11 GBG72673.1 - 0.13 12.1 2.4 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein TRAP_alpha PF03896.16 GBG72674.1 - 1.9e-32 112.6 0.0 2.5e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Peptidase_S49_N PF08496.10 GBG72674.1 - 0.011 15.8 1.0 0.015 15.3 1.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal R_equi_Vir PF05526.11 GBG72674.1 - 0.13 12.1 2.4 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein 2OG-FeII_Oxy_3 PF13640.6 GBG72676.1 - 2.8e-13 50.6 0.0 9.7e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GBG72676.1 - 1e-07 32.4 0.0 1.8e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 GBG72677.1 - 2.3e-13 50.8 0.0 9.6e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GBG72677.1 - 1e-07 32.4 0.0 1.8e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Synaphin PF05835.12 GBG72678.1 - 0.13 12.5 11.8 0.14 12.4 2.8 2.1 2 0 0 2 2 2 0 Synaphin protein RT_RNaseH_2 PF17919.1 GBG72679.1 - 5.3e-25 87.4 0.1 5.8e-24 84.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72679.1 - 1.1e-23 83.5 0.0 3.8e-23 81.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72679.1 - 1.8e-18 66.4 0.1 3.8e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72679.1 - 6.8e-09 35.9 0.0 4.2e-08 33.4 0.0 2.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG72679.1 - 0.0013 19.2 0.0 0.003 18.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72679.1 - 0.0018 18.9 0.0 0.0047 17.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG72679.1 - 0.11 12.8 0.0 0.47 10.8 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein DehI PF10778.9 GBG72679.1 - 0.3 11.2 2.3 0.56 10.3 0.0 2.4 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI TolA_bind_tri PF16331.5 GBG72679.1 - 0.68 10.1 6.4 0.93 9.6 0.8 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation BssS PF13991.6 GBG72680.1 - 4.2 7.5 10.3 0.42 10.7 1.7 4.1 3 0 0 3 3 3 0 BssS protein family BssS PF13991.6 GBG72681.1 - 4.8 7.3 10.3 0.41 10.7 1.7 3.9 3 0 0 3 3 3 0 BssS protein family RVT_1 PF00078.27 GBG72683.1 - 5.6e-29 101.2 0.0 8.9e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72683.1 - 4.3e-24 84.4 0.0 2.1e-23 82.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72683.1 - 3.6e-19 69.0 0.0 1.4e-18 67.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RasGEF_N PF00618.20 GBG72685.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 RasGEF N-terminal motif PAF-AH_p_II PF03403.13 GBG72685.1 - 1.7 7.0 5.6 2.9 6.3 5.6 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II RT_RNaseH_2 PF17919.1 GBG72686.1 - 6.3e-28 96.7 0.1 3.4e-27 94.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72686.1 - 5.4e-26 90.9 0.4 4.3e-25 88.0 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG72686.1 - 4.1e-10 39.4 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG72686.1 - 0.0054 16.3 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72687.1 - 1.5e-28 99.2 0.0 4.5e-28 97.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72687.1 - 1.9e-26 92.0 0.0 5.9e-13 48.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72687.1 - 2.8e-18 66.2 0.1 6.3e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NUDIX PF00293.28 GBG72688.1 - 7.7e-09 35.7 0.1 1.3e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain SF1-HH PF16275.5 GBG72690.1 - 1.8e-30 105.6 0.9 4.4e-30 104.3 0.9 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain RRM_1 PF00076.22 GBG72690.1 - 2.8e-20 71.9 0.0 5.1e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.29 GBG72690.1 - 2.4e-07 30.5 0.2 5.1e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 KH domain eIF3g PF12353.8 GBG72690.1 - 0.0029 18.0 3.5 0.069 13.6 0.4 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 GBG72690.1 - 0.011 15.8 8.9 0.074 13.2 2.4 2.9 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 GBG72690.1 - 0.014 15.5 1.2 0.027 14.5 1.2 1.5 1 0 0 1 1 1 0 PHD-finger RRM_5 PF13893.6 GBG72690.1 - 0.056 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.6 GBG72690.1 - 0.52 10.3 3.1 11 6.1 1.0 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG72690.1 - 1.9 8.4 11.0 1.4 8.8 2.1 2.5 2 0 0 2 2 2 0 Zinc knuckle RNA_pol_Rpb5_N PF03871.14 GBG72691.1 - 3.3e-33 114.1 0.6 5.7e-33 113.3 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 GBG72691.1 - 5.5e-33 112.7 0.8 1e-32 111.8 0.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.12 GBG72691.1 - 0.082 12.9 0.1 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 Restriction endonuclease Myb_DNA-bind_4 PF13837.6 GBG72692.1 - 3.2e-08 33.8 0.3 5.8e-08 33.0 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72692.1 - 0.069 13.5 0.2 0.13 12.6 0.2 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG72692.1 - 0.081 13.1 2.6 0.26 11.5 2.6 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG72692.1 - 0.22 11.6 2.4 0.35 11.0 2.4 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG72693.1 - 9.8e-28 96.8 0.0 1.4e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72693.1 - 1.4e-16 60.7 0.0 2.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72693.1 - 0.00018 21.2 0.3 0.63 9.7 0.0 2.6 2 1 0 2 2 2 2 Transposase DDE domain Integrase_H2C2 PF17921.1 GBG72694.1 - 2e-15 56.6 0.1 6e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG72694.1 - 4.6e-09 36.7 0.3 7e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG72694.1 - 1.9e-07 31.3 0.0 7.1e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG72694.1 - 2.2e-05 25.0 0.2 0.0001 22.9 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG72694.1 - 0.00088 19.1 0.5 0.0017 18.2 0.5 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG72694.1 - 0.0011 19.2 0.0 0.0036 17.6 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG72694.1 - 0.0023 18.1 0.0 0.0068 16.6 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Lamprin PF06403.11 GBG72694.1 - 0.66 9.9 14.6 1.3 9.0 14.6 1.4 1 0 0 1 1 1 0 Lamprin RVT_1 PF00078.27 GBG72695.1 - 1.5e-56 191.4 0.2 4.1e-28 98.4 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72695.1 - 1.3e-13 50.8 0.1 4.1e-13 49.2 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72695.1 - 5.2e-11 42.8 0.0 1.3e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72695.1 - 0.0014 18.8 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF4399 PF14347.6 GBG72695.1 - 0.0082 16.5 0.0 8.9 6.8 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4399) Asp_protease_2 PF13650.6 GBG72695.1 - 0.0089 16.7 0.0 0.029 15.0 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease LIME1 PF15332.6 GBG72695.1 - 0.26 10.9 2.5 0.56 9.8 2.5 1.5 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 RT_RNaseH_2 PF17919.1 GBG72697.1 - 5.2e-32 109.8 0.2 1.3e-31 108.6 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72697.1 - 1.9e-31 109.3 0.1 3.3e-31 108.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72697.1 - 1.2e-26 93.0 0.1 2.9e-26 91.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG72697.1 - 3.4e-07 30.4 1.1 0.00087 19.5 0.0 4.0 3 0 0 3 3 3 2 Retrotransposon gag protein DUF4288 PF14119.6 GBG72697.1 - 0.034 14.5 2.6 0.092 13.2 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) zf-CCHC_4 PF14392.6 GBG72698.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG72698.1 - 0.05 13.7 3.7 0.079 13.1 3.7 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG72698.1 - 0.12 12.2 2.0 0.12 12.2 0.5 1.8 2 0 0 2 2 2 0 Zinc knuckle P21-Arc PF04062.14 GBG72698.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit LMBR1 PF04791.16 GBG72699.1 - 0.0018 17.3 4.1 0.003 16.5 4.1 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein PEP-utilisers_N PF05524.13 GBG72699.1 - 0.58 10.4 15.5 0.092 12.9 4.6 2.8 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal Mitofilin PF09731.9 GBG72699.1 - 0.62 8.8 36.7 0.046 12.6 9.0 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DNA_pack_N PF02500.15 GBG72699.1 - 1.3 8.7 5.8 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus DUF4820 PF16091.5 GBG72699.1 - 1.6 8.1 13.3 0.045 13.1 5.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF5069 PF16798.5 GBG72699.1 - 1.6 8.9 9.2 0.21 11.8 0.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) DUF1664 PF07889.12 GBG72699.1 - 2.8 8.0 14.6 0.032 14.3 2.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RVT_1 PF00078.27 GBG72700.1 - 2.9e-28 98.9 0.1 4.7e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72700.1 - 1.4e-25 89.2 0.0 3.9e-25 87.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72700.1 - 7.8e-22 77.6 0.0 1.8e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72700.1 - 1.3e-12 47.7 1.4 2.1e-12 46.9 0.1 2.1 3 0 0 3 3 3 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG72700.1 - 2.3e-07 31.3 0.0 4.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72700.1 - 2.5e-07 31.3 0.0 5.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG72700.1 - 7e-06 25.9 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG72700.1 - 8.1e-05 22.5 0.0 0.001 18.9 0.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG72700.1 - 0.0029 17.4 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG72700.1 - 0.081 13.2 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG72701.1 - 0.024 14.9 1.3 0.085 13.1 0.1 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein ZapB PF06005.12 GBG72701.1 - 0.025 15.0 2.3 0.025 15.0 2.3 3.9 3 2 1 4 4 4 0 Cell division protein ZapB RVT_1 PF00078.27 GBG72702.1 - 5.7e-34 117.6 0.0 1e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72702.1 - 1.2e-30 105.8 0.1 3.8e-30 104.3 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72702.1 - 8.7e-30 102.7 0.0 1.1e-28 99.2 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG72702.1 - 0.092 12.4 0.0 0.092 12.4 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH PF17917.1 GBG72703.1 - 3.7e-77 255.4 8.0 3.4e-29 101.2 0.1 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72703.1 - 5.5e-76 251.0 1.8 1.3e-31 108.6 0.0 4.0 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72703.1 - 2.2e-53 178.2 10.0 7.4e-18 64.4 0.2 3.6 3 0 0 3 3 3 3 Integrase zinc binding domain RVT_1 PF00078.27 GBG72703.1 - 4.4e-50 170.3 0.6 5.2e-29 101.3 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG72703.1 - 2.4e-43 147.1 1.4 3.1e-13 49.9 0.1 4.8 4 0 0 4 4 4 4 Integrase core domain gag-asp_proteas PF13975.6 GBG72703.1 - 7.2e-05 23.3 0.0 0.00029 21.3 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG72703.1 - 0.00061 20.0 1.0 0.3 11.4 0.0 3.3 3 0 0 3 3 3 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG72703.1 - 0.00087 19.9 0.0 0.0025 18.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease DUF4834 PF16118.5 GBG72703.1 - 0.0011 19.9 0.4 0.0043 18.0 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 GBG72703.1 - 0.0013 19.5 0.2 0.0048 17.7 0.2 1.9 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1564 PF07600.11 GBG72703.1 - 0.0054 16.4 0.0 0.78 9.4 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Chromo PF00385.24 GBG72703.1 - 0.025 14.5 0.0 3.1 7.8 0.0 3.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain TMEM154 PF15102.6 GBG72703.1 - 0.099 12.5 1.4 0.3 11.0 1.4 1.7 1 0 0 1 1 1 0 TMEM154 protein family SID-1_RNA_chan PF13965.6 GBG72703.1 - 0.14 10.5 2.0 0.23 9.8 2.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 dCMP_cyt_deam_1 PF00383.23 GBG72703.1 - 0.54 10.2 1.6 1.4 8.8 1.6 1.7 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Baculo_11_kDa PF06143.11 GBG72703.1 - 1.1 8.9 5.9 3.2 7.4 5.9 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family ODV-E18 PF10717.9 GBG72703.1 - 1.8 8.5 14.1 5.1 7.0 14.1 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF929 PF06053.11 GBG72703.1 - 2.6 7.3 9.3 5.3 6.3 9.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF929) SR-25 PF10500.9 GBG72703.1 - 2.9 7.4 26.4 0.0055 16.4 10.8 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.7 GBG72704.1 - 1.7 8.5 10.5 2.9 7.7 10.5 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein RT_RNaseH PF17917.1 GBG72705.1 - 5.4e-15 55.6 1.1 9.7e-15 54.7 1.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72705.1 - 1.4e-14 54.0 0.2 4.4e-14 52.3 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72705.1 - 2.2e-14 53.7 0.0 7.4e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG72705.1 - 9.9e-08 31.9 0.2 1.9e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Lipase_3 PF01764.25 GBG72706.1 - 5.9e-22 78.1 0.0 2.1e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) RT_RNaseH_2 PF17919.1 GBG72706.1 - 1.2e-13 50.9 0.0 2.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72706.1 - 4.7e-13 49.2 0.0 8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG72706.1 - 0.00085 19.3 2.1 0.0018 18.3 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH PF17917.1 GBG72706.1 - 0.0091 16.3 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Abhydrolase_6 PF12697.7 GBG72706.1 - 0.054 14.1 0.0 0.054 14.1 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 GBG72706.1 - 0.13 11.9 0.4 0.99 9.0 0.0 2.2 2 0 0 2 2 2 0 Putative esterase DUF2058 PF09831.9 GBG72706.1 - 0.6 10.2 11.5 1.8 8.7 11.5 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Adeno_E1B_55K_N PF04623.12 GBG72707.1 - 0.28 11.9 7.7 1.7 9.4 3.0 2.7 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus RT_RNaseH_2 PF17919.1 GBG72708.1 - 8.7e-35 118.8 0.1 1.5e-34 118.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72708.1 - 7.3e-31 106.6 0.1 1.3e-30 105.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BTRD1 PF17660.1 GBG72708.1 - 0.0034 17.2 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial tandem repeat domain 1 Integrase_H2C2 PF17921.1 GBG72708.1 - 0.16 12.1 0.1 0.48 10.6 0.1 1.8 2 0 0 2 2 2 0 Integrase zinc binding domain RVT_1 PF00078.27 GBG72709.1 - 2.3e-27 95.9 0.1 5.4e-27 94.8 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HIP1_clath_bdg PF16515.5 GBG72709.1 - 0.0053 17.3 2.3 0.0053 17.3 2.3 3.2 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 RVP_2 PF08284.11 GBG72709.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG72709.1 - 0.014 15.6 4.2 0.016 15.4 0.1 3.2 2 1 0 2 2 2 0 Retrotransposon gag protein SLATT_6 PF18169.1 GBG72709.1 - 0.099 12.2 0.1 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 NPV_P10 PF05531.12 GBG72709.1 - 0.3 11.6 2.1 1.2 9.6 0.2 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 GBG72709.1 - 0.63 10.1 1.9 71 3.5 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 GBG72709.1 - 7.5 5.8 19.2 0.059 12.7 5.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF2057 PF09829.9 GBG72709.1 - 10 6.3 6.9 66 3.6 0.5 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) Myb_DNA-bind_4 PF13837.6 GBG72710.1 - 8.6e-07 29.3 0.5 1.7e-06 28.3 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG72710.1 - 0.00025 21.1 0.9 0.00048 20.1 0.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72710.1 - 0.012 15.9 0.1 0.027 14.8 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RRM_1 PF00076.22 GBG72713.1 - 4.7e-20 71.2 0.0 5.9e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG72713.1 - 0.0097 16.0 0.0 0.029 14.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif zf-CCHC PF00098.23 GBG72714.1 - 6.5e-05 22.8 1.6 0.00025 21.0 1.6 2.1 1 0 0 1 1 1 1 Zinc knuckle Ring_hydroxyl_A PF00848.19 GBG72714.1 - 0.037 14.0 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) SDA1 PF05285.12 GBG72715.1 - 0.087 12.2 13.9 0.11 11.9 13.9 1.2 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 GBG72715.1 - 0.27 11.0 8.1 0.42 10.4 8.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG72715.1 - 0.45 9.2 5.0 0.63 8.8 5.0 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG72715.1 - 0.83 7.8 17.7 0.96 7.6 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG72715.1 - 1.2 7.3 13.9 1.5 7.0 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 GBG72715.1 - 1.6 7.9 10.3 2.5 7.2 10.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HSP70 PF00012.20 GBG72715.1 - 3.9 5.5 8.1 5.1 5.2 8.1 1.1 1 0 0 1 1 1 0 Hsp70 protein RVT_1 PF00078.27 GBG72716.1 - 1.8e-29 102.8 0.0 3.1e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG72716.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Whi5 PF08528.11 GBG72716.1 - 0.17 11.5 0.0 0.45 10.2 0.0 1.8 1 0 0 1 1 1 0 Whi5 like RT_RNaseH PF17917.1 GBG72717.1 - 7.1e-30 103.4 0.0 1.5e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72717.1 - 7.4e-29 99.7 0.0 1.5e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72717.1 - 7.3e-27 94.3 0.0 1.3e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG72717.1 - 3.5e-06 26.8 0.0 6.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG72717.1 - 0.00022 21.7 0.0 0.00064 20.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72717.1 - 0.0031 18.1 0.0 0.0074 16.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG72717.1 - 0.033 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease PIF1 PF05970.14 GBG72718.1 - 1.6e-63 215.1 0.0 2.1e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 GBG72718.1 - 0.059 13.1 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain RT_RNaseH PF17917.1 GBG72719.1 - 9.4e-29 99.8 0.1 1.5e-27 95.9 0.1 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72719.1 - 1.9e-28 98.4 0.5 2.4e-27 94.9 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72719.1 - 2.2e-18 66.1 0.7 5.5e-18 64.8 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72719.1 - 3.2e-17 62.8 0.1 1.7e-16 60.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG72719.1 - 9.4e-05 22.0 0.1 0.00025 20.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG72719.1 - 0.0041 17.3 0.1 0.013 15.7 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Phage_lysozyme PF00959.19 GBG72719.1 - 0.018 15.5 1.0 6.6 7.2 0.0 3.3 3 0 0 3 3 3 0 Phage lysozyme Integrase_H2C2 PF17921.1 GBG72720.1 - 8.9e-19 67.4 0.2 1.9e-18 66.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG72720.1 - 0.0025 18.0 0.0 0.01 16.0 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG72720.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF4148 PF13663.6 GBG72720.1 - 0.13 12.4 3.2 0.5 10.6 3.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Uds1 PF15456.6 GBG72720.1 - 0.2 11.9 7.2 0.56 10.4 4.0 2.9 2 0 0 2 2 2 0 Up-regulated During Septation Pkinase PF00069.25 GBG72721.1 - 1.2e-117 392.0 0.0 1.5e-55 188.4 0.0 4.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GBG72721.1 - 8.4e-91 303.8 0.0 4.8e-44 150.6 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GBG72721.1 - 1.2e-12 47.8 0.0 2.5e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 GBG72721.1 - 2e-08 33.5 2.1 0.0076 15.1 0.0 3.7 4 0 0 4 4 4 2 Fungal protein kinase Kdo PF06293.14 GBG72721.1 - 1.2e-05 24.8 0.1 0.21 10.9 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG72721.1 - 0.00067 19.6 0.4 0.032 14.1 0.0 4.3 5 0 0 5 5 5 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG72721.1 - 0.0046 16.0 7.5 0.72 8.7 0.0 3.8 5 0 0 5 5 5 2 Haspin like kinase domain DUF2722 PF10846.8 GBG72721.1 - 0.14 11.1 7.6 0.28 10.1 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MMR1 PF08505.10 GBG72721.1 - 0.18 12.1 5.3 0.52 10.6 5.3 1.7 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 GBG72721.1 - 1.1 9.2 14.0 0.0094 16.0 5.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF659 PF04937.15 GBG72722.1 - 3.3e-31 108.2 0.0 5.4e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG72722.1 - 5.1e-07 29.4 0.1 2e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG72723.1 - 5e-33 114.1 0.0 9.1e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG72723.1 - 1.4e-08 34.3 0.1 3.3e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region BPA_C PF18040.1 GBG72725.1 - 0.031 14.2 1.2 2.6 8.0 0.4 2.4 2 0 0 2 2 2 0 beta porphyranase A C-terminal RT_RNaseH_2 PF17919.1 GBG72727.1 - 2.8e-21 75.4 0.0 6e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72727.1 - 1.8e-19 69.9 0.0 4.2e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72727.1 - 3.2e-15 56.0 0.7 3.2e-15 56.0 0.7 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG72727.1 - 1.3e-10 41.1 0.1 2.4e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C_2 PF13307.6 GBG72727.1 - 9.1e-09 35.7 0.3 1.6e-08 34.9 0.3 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain rve PF00665.26 GBG72727.1 - 3.7e-07 30.3 0.0 1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG72727.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DEAD_2 PF06733.15 GBG72728.1 - 1.9e-40 138.3 0.0 4.7e-40 137.1 0.0 1.7 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 GBG72728.1 - 1.8e-18 67.3 0.0 2.2e-17 63.7 0.0 2.6 1 1 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 GBG72728.1 - 0.00052 19.7 3.4 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 1 Helical and beta-bridge domain ResIII PF04851.15 GBG72728.1 - 0.0053 16.8 0.0 0.94 9.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG72728.1 - 0.015 15.1 0.0 0.48 10.2 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase SNF2_N PF00176.23 GBG72728.1 - 0.097 11.4 0.0 0.39 9.4 0.0 1.9 2 0 0 2 2 2 0 SNF2 family N-terminal domain DEAD_2 PF06733.15 GBG72729.1 - 1.3e-28 99.8 0.0 2.8e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 GBG72729.1 - 5.4e-19 69.0 0.0 7.3e-18 65.3 0.0 2.4 1 1 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 GBG72729.1 - 0.00024 20.8 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Helical and beta-bridge domain Exo_endo_phos PF03372.23 GBG72729.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SNF2_N PF00176.23 GBG72729.1 - 0.021 13.6 0.0 0.041 12.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain DEAD_2 PF06733.15 GBG72730.1 - 2.2e-05 24.1 1.1 3e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 GBG72730.1 - 0.15 12.0 0.0 0.47 10.4 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG72730.1 - 0.16 11.7 0.4 0.38 10.5 0.0 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase Kinesin PF00225.23 GBG72732.1 - 1.6e-83 280.4 0.0 1.6e-83 280.4 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GBG72732.1 - 1.4e-20 73.8 0.0 3.8e-16 59.3 0.0 2.6 2 0 0 2 2 2 2 Microtubule binding AAA_11 PF13086.6 GBG72732.1 - 0.081 12.7 3.6 0.11 12.3 2.8 1.6 2 0 0 2 2 2 0 AAA domain Connexin PF00029.19 GBG72732.1 - 0.4 10.4 5.6 0.7 9.6 5.6 1.3 1 0 0 1 1 1 0 Connexin DUF4604 PF15377.6 GBG72732.1 - 0.78 10.1 20.4 1.6 9.2 20.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Presenilin PF01080.17 GBG72732.1 - 1.5 7.5 6.7 2.3 6.9 6.7 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 GBG72732.1 - 3.8 5.3 5.2 5.4 4.8 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Afi1 PF07792.12 GBG72732.1 - 6 7.4 7.4 12 6.4 7.4 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking rve PF00665.26 GBG72733.1 - 2.9e-12 46.8 0.0 6.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG72733.1 - 0.0021 17.8 0.0 0.0095 15.7 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Fur_reg_FbpB PF13040.6 GBG72733.1 - 0.13 11.8 1.0 0.26 10.9 1.0 1.4 1 0 0 1 1 1 0 Fur-regulated basic protein B Retrotrans_gag PF03732.17 GBG72734.1 - 0.0012 19.0 0.6 0.0076 16.5 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_6 PF15288.6 GBG72734.1 - 0.095 12.6 1.5 0.23 11.3 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG72734.1 - 0.16 11.8 3.2 0.25 11.2 3.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG72735.1 - 2.1e-07 31.2 1.1 3.9e-07 30.4 1.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG72735.1 - 0.0032 17.6 3.1 0.012 15.7 3.1 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72735.1 - 0.027 14.8 0.4 0.062 13.6 0.4 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG72735.1 - 0.092 13.0 0.4 0.23 11.7 0.4 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG72735.1 - 0.16 12.0 1.6 0.29 11.2 1.6 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG72736.1 - 2.4e-26 92.3 0.0 4.4e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72736.1 - 1.5e-08 34.5 0.0 2.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DUF2345 PF10106.9 GBG72736.1 - 0.002 18.0 1.3 0.0038 17.1 1.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) DDE_Tnp_1 PF01609.21 GBG72736.1 - 0.18 11.5 0.3 8 6.0 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG72737.1 - 1.7e-05 25.1 4.3 1.7e-05 25.1 4.3 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG72737.1 - 0.0093 16.0 2.1 0.0093 16.0 2.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72737.1 - 0.38 11.1 6.7 0.063 13.6 2.4 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG72738.1 - 5.4e-29 100.9 0.0 7.9e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72738.1 - 4.9e-14 52.4 0.0 7.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72738.1 - 2.6e-05 24.0 0.1 0.24 11.0 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain Gln-synt_C PF00120.24 GBG72739.1 - 1.6e-15 57.0 0.0 1.3e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG72739.1 - 4.8e-11 42.2 0.0 8.3e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PGA2 PF07543.12 GBG72740.1 - 7.6 6.5 6.8 0.71 9.9 2.2 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 Gln-synt_C PF00120.24 GBG72743.1 - 1.5e-15 57.0 0.0 1.2e-12 47.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG72743.1 - 4.7e-11 42.3 0.0 8.2e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain ATP-synt_C PF00137.21 GBG72744.1 - 8.5e-34 115.7 35.8 3.1e-20 72.3 13.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Man-6-P_recep PF02157.15 GBG72744.1 - 0.21 10.7 1.0 1.9 7.5 0.3 2.2 1 1 2 3 3 3 0 Mannose-6-phosphate receptor SecE PF00584.20 GBG72744.1 - 0.56 10.2 0.1 0.56 10.2 0.1 2.2 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Glycophorin_A PF01102.18 GBG72744.1 - 7.1 6.9 5.1 1 9.7 1.0 1.7 2 0 0 2 2 2 0 Glycophorin A DDE_Tnp_4 PF13359.6 GBG72745.1 - 5.7e-27 94.3 0.0 8.6e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72745.1 - 4.4e-15 55.8 0.0 6.1e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72745.1 - 0.01 15.5 0.2 0.081 12.6 0.0 2.1 2 0 0 2 2 2 0 Transposase DDE domain Enolase_C PF00113.22 GBG72746.1 - 2.8e-160 532.4 0.5 3.5e-160 532.0 0.5 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GBG72746.1 - 7.8e-56 187.8 0.0 1.6e-55 186.9 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GBG72746.1 - 5e-11 42.6 0.0 8.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GBG72746.1 - 3.1e-06 26.5 0.0 6.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF572 PF04502.13 GBG72747.1 - 0.84 9.2 15.4 1.2 8.7 15.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2828 PF11443.8 GBG72747.1 - 4.1 5.4 9.5 5.6 4.9 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PDCD2_C PF04194.13 GBG72747.1 - 7.8 6.5 10.3 12 5.9 10.3 1.3 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain RVT_1 PF00078.27 GBG72748.1 - 7.6e-31 107.3 0.1 2.5e-30 105.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72748.1 - 1.4e-08 35.0 0.0 4.3e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72748.1 - 0.00027 20.9 0.0 0.0015 18.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HIP1_clath_bdg PF16515.5 GBG72748.1 - 0.00044 20.8 6.8 0.00044 20.8 6.8 3.6 4 0 0 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 RVP_2 PF08284.11 GBG72748.1 - 0.0038 17.0 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG72748.1 - 0.019 15.5 0.0 0.076 13.6 0.0 2.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72748.1 - 0.027 15.1 0.0 0.1 13.3 0.0 2.0 1 1 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG72748.1 - 0.049 13.9 0.1 0.049 13.9 0.1 4.4 4 1 0 4 4 4 0 Retrotransposon gag protein COMP PF11598.8 GBG72748.1 - 0.19 12.2 4.6 0.57 10.7 4.6 1.8 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein BLOC1_2 PF10046.9 GBG72748.1 - 0.32 11.3 7.5 0.2 12.0 2.5 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 GBG72748.1 - 0.7 9.9 4.2 10 6.2 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 GBG72748.1 - 1.1 9.8 5.3 26 5.3 0.2 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 GBG72748.1 - 1.6 9.2 10.2 0.082 13.3 3.0 2.6 3 0 0 3 3 3 0 Snapin/Pallidin Atg14 PF10186.9 GBG72748.1 - 2.6 7.1 9.8 0.058 12.5 0.5 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 GBG72748.1 - 6.9 6.1 10.9 11 5.4 9.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit PIN_12 PF16289.5 GBG72749.1 - 0.024 15.1 6.6 0.063 13.8 6.6 1.7 1 0 0 1 1 1 0 PIN domain HAD_SAK_2 PF18143.1 GBG72749.1 - 0.025 14.9 1.2 0.051 13.9 1.2 1.5 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins UPF0184 PF03670.13 GBG72749.1 - 0.12 12.8 0.4 0.12 12.8 0.4 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) DAG_kinase_N PF14513.6 GBG72749.1 - 0.25 11.6 4.8 0.076 13.2 1.1 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DASH_Dad2 PF08654.10 GBG72749.1 - 1.7 9.1 13.5 1.5 9.3 1.9 3.1 1 1 1 2 2 2 0 DASH complex subunit Dad2 DUF1840 PF08895.11 GBG72749.1 - 4 7.8 15.2 0.28 11.5 8.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) Baculo_PEP_C PF04513.12 GBG72749.1 - 4.2 7.4 8.0 37 4.4 2.7 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_60s PF00428.19 GBG72749.1 - 7 7.3 8.6 0.28 11.8 0.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Plasmid_RAQPRD PF09686.10 GBG72749.1 - 7.3 6.9 10.7 0.16 12.2 1.2 2.9 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Retrotrans_gag PF03732.17 GBG72750.1 - 0.071 13.4 0.0 2.4 8.5 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG72751.1 - 5.9e-30 103.3 0.0 1.1e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72751.1 - 2.8e-26 91.8 0.0 5.4e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72751.1 - 8.2e-15 54.7 0.1 2.2e-14 53.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72751.1 - 4.2e-10 39.9 0.0 1.3e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72751.1 - 0.0014 18.8 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger GCN5L1 PF06320.13 GBG72751.1 - 0.027 14.6 1.0 0.18 12.0 0.4 2.5 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Phage_GPO PF05929.11 GBG72751.1 - 0.13 11.8 3.6 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase AOX PF01786.17 GBG72752.1 - 0.096 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Alternative oxidase RVT_1 PF00078.27 GBG72753.1 - 2.4e-19 69.7 0.0 4.2e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Protocadherin PF08374.11 GBG72753.1 - 0.0016 18.5 3.6 0.0016 18.5 3.6 38.3 2 2 6 8 8 8 1 Protocadherin DDHD PF02862.17 GBG72753.1 - 0.27 11.4 2.4 4.7 7.3 0.0 2.1 2 0 0 2 2 2 0 DDHD domain HemX PF04375.14 GBG72753.1 - 0.7 9.1 23.3 11 5.1 16.6 4.3 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase SlyX PF04102.12 GBG72756.1 - 0.012 16.2 0.6 0.12 13.1 0.0 2.5 2 0 0 2 2 2 0 SlyX DUF977 PF06163.11 GBG72756.1 - 0.044 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Cnn_1N PF07989.11 GBG72756.1 - 0.064 13.4 1.1 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 GBG72756.1 - 0.24 10.7 7.3 0.33 10.3 6.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PilO PF04350.13 GBG72756.1 - 0.45 10.7 3.1 10 6.2 1.0 2.2 1 1 1 2 2 2 0 Pilus assembly protein, PilO FAM76 PF16046.5 GBG72756.1 - 4.9 6.4 7.9 9.5 5.5 7.7 1.6 1 1 0 1 1 1 0 FAM76 protein NPR3 PF03666.13 GBG72756.1 - 6.1 5.5 8.3 6.7 5.4 8.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PRKG1_interact PF15898.5 GBG72756.1 - 8.3 7.4 13.7 0.36 11.8 0.6 3.2 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Retrotrans_gag PF03732.17 GBG72757.1 - 2e-05 24.8 3.2 0.0011 19.3 0.0 3.4 3 0 0 3 3 3 2 Retrotransposon gag protein Nop14 PF04147.12 GBG72758.1 - 0.23 9.6 5.4 0.26 9.5 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG72758.1 - 0.99 7.6 5.7 1.2 7.3 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein ThiF PF00899.21 GBG72759.1 - 2.4e-43 148.2 0.0 3.8e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 GBG72759.1 - 0.00013 22.3 0.2 0.00032 21.0 0.2 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 GBG72759.1 - 0.028 14.9 0.1 0.077 13.5 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 GBG72759.1 - 0.056 13.7 0.3 0.18 12.1 0.3 1.9 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 GBG72759.1 - 0.71 9.4 3.2 0.41 10.2 0.4 2.1 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AP3D1 PF06375.11 GBG72760.1 - 0.00034 20.9 17.8 0.00039 20.7 17.8 1.1 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 BRF1 PF07741.13 GBG72760.1 - 0.0094 16.3 14.7 0.011 16.0 14.7 1.2 1 0 0 1 1 1 1 Brf1-like TBP-binding domain ATP-synt_E PF05680.12 GBG72760.1 - 0.2 12.0 10.8 0.24 11.7 10.8 1.2 1 0 0 1 1 1 0 ATP synthase E chain SR-25 PF10500.9 GBG72760.1 - 0.45 10.1 28.8 0.51 9.9 28.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNApol_Exo PF18136.1 GBG72760.1 - 0.47 9.5 7.2 0.57 9.3 7.2 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain DDE_Tnp_IS1595 PF12762.7 GBG72760.1 - 0.96 9.4 7.9 1.2 9.2 7.9 1.2 1 0 0 1 1 1 0 ISXO2-like transposase domain Eapp_C PF10238.9 GBG72760.1 - 1 9.5 11.4 1.2 9.2 11.4 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein MAP17 PF15807.5 GBG72760.1 - 1.1 9.5 12.8 1.3 9.3 12.8 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Rtf2 PF04641.12 GBG72760.1 - 1.3 8.3 18.4 1.5 8.1 18.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Protocadherin PF08374.11 GBG72760.1 - 1.6 8.7 12.2 1.8 8.5 12.2 1.0 1 0 0 1 1 1 0 Protocadherin Presenilin PF01080.17 GBG72760.1 - 1.8 7.2 5.8 1.9 7.2 5.8 1.0 1 0 0 1 1 1 0 Presenilin DUF1168 PF06658.12 GBG72760.1 - 1.8 8.4 26.5 2.2 8.1 26.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Cellulose_synt PF03552.14 GBG72760.1 - 2.6 6.4 5.9 2.7 6.4 5.9 1.0 1 0 0 1 1 1 0 Cellulose synthase GAGA_bind PF06217.12 GBG72760.1 - 2.9 8.1 18.7 3.4 7.9 18.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Connexin PF00029.19 GBG72760.1 - 3.3 7.4 11.2 3.5 7.3 11.2 1.1 1 0 0 1 1 1 0 Connexin Glucan_synthase PF02364.15 GBG72760.1 - 3.6 5.6 6.2 3.7 5.6 6.2 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Coilin_N PF15862.5 GBG72760.1 - 3.8 7.3 20.1 4.2 7.2 20.1 1.1 1 0 0 1 1 1 0 Coilin N-terminus PPL5 PF18168.1 GBG72760.1 - 4.1 6.6 10.2 4.6 6.4 10.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Zip PF02535.22 GBG72760.1 - 5.1 6.2 6.0 5.5 6.1 6.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter EOS1 PF12326.8 GBG72760.1 - 5.2 7.0 5.0 5.5 6.9 5.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein Jak1_Phl PF17887.1 GBG72760.1 - 5.7 6.9 13.1 7.3 6.6 13.1 1.2 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain SHR3_chaperone PF08229.11 GBG72760.1 - 5.8 5.8 8.3 7.8 5.4 8.3 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 O-antigen_lig PF13425.6 GBG72760.1 - 6.9 5.3 6.5 7.3 5.3 6.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Folate_carrier PF01770.18 GBG72760.1 - 7.4 5.2 6.4 8.4 5.0 6.4 1.0 1 0 0 1 1 1 0 Reduced folate carrier Sec62 PF03839.16 GBG72760.1 - 7.7 6.0 16.2 8.7 5.8 16.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Ureide_permease PF07168.11 GBG72760.1 - 8 5.1 4.9 8.2 5.1 4.9 1.0 1 0 0 1 1 1 0 Ureide permease Myb_DNA-bind_4 PF13837.6 GBG72763.1 - 1.3e-08 35.0 1.8 2.4e-08 34.2 1.8 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72763.1 - 0.00063 20.0 0.8 0.0015 18.8 0.8 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG72763.1 - 0.00082 19.5 0.4 0.0016 18.6 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG72763.1 - 0.00092 19.4 1.0 0.002 18.3 1.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG72763.1 - 0.0054 16.8 0.4 0.0093 16.0 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG72764.1 - 1.7e-22 79.8 1.0 8.1e-22 77.6 0.0 2.6 3 1 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72764.1 - 1.4e-10 41.1 0.0 7.8e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72764.1 - 0.0007 19.3 0.3 0.052 13.2 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG72764.1 - 0.039 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Transposase DDE domain MMR_HSR1 PF01926.23 GBG72765.1 - 9e-06 25.8 0.0 5.2e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GBG72765.1 - 6.8e-05 22.3 0.8 0.33 10.3 0.0 3.5 4 0 0 4 4 4 2 AIG1 family AAA_16 PF13191.6 GBG72765.1 - 0.00013 22.4 0.1 0.00078 19.9 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GBG72765.1 - 0.00019 21.4 0.0 0.00054 19.9 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase G-alpha PF00503.20 GBG72765.1 - 0.0006 19.1 0.5 0.0016 17.6 0.0 1.9 2 0 0 2 2 2 1 G-protein alpha subunit AAA_29 PF13555.6 GBG72765.1 - 0.00091 18.9 0.0 0.0031 17.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 GBG72765.1 - 0.0027 17.0 0.1 0.0071 15.7 0.1 1.7 1 1 0 1 1 1 1 Septin IIGP PF05049.13 GBG72765.1 - 0.0072 15.4 0.0 0.034 13.2 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 GBG72765.1 - 0.011 15.8 0.0 4.5 7.3 0.0 2.8 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 GBG72765.1 - 0.012 15.9 0.0 0.3 11.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GBG72765.1 - 0.013 14.7 0.1 0.11 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 GBG72765.1 - 0.02 15.4 0.2 0.02 15.4 0.2 2.7 3 0 0 3 3 2 0 AAA domain T2SSE PF00437.20 GBG72765.1 - 0.021 13.9 1.0 0.035 13.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 GBG72765.1 - 0.03 14.8 0.0 0.15 12.6 0.0 2.2 1 0 0 1 1 1 0 ABC transporter TniB PF05621.11 GBG72765.1 - 0.073 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 GBG72765.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 GBG72765.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GBG72765.1 - 0.11 12.9 0.0 0.41 11.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DSBA PF01323.20 GBG72765.1 - 0.13 12.0 0.4 0.49 10.2 0.1 2.0 2 0 0 2 2 2 0 DSBA-like thioredoxin domain TsaE PF02367.17 GBG72765.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rhodanese_C PF12368.8 GBG72765.1 - 0.9 10.0 9.3 1.2 9.6 3.0 2.9 2 0 0 2 2 2 0 Rhodanase C-terminal BUD22 PF09073.10 GBG72766.1 - 1 8.7 20.9 1.4 8.2 20.9 1.1 1 0 0 1 1 1 0 BUD22 MSA-2c PF12238.8 GBG72766.1 - 2.5 8.0 6.1 3.9 7.4 6.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Aldo_ket_red PF00248.21 GBG72767.1 - 4.1e-70 236.3 0.0 4.6e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ACOX PF01756.19 GBG72769.1 - 1.6e-31 109.2 0.1 1.8e-31 109.1 0.1 1.0 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 GBG72770.1 - 8.4e-17 61.2 0.0 1.5e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GBG72770.1 - 1.1e-10 41.9 0.1 2.2e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NLRC4_HD2 PF17776.1 GBG72770.1 - 0.084 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 NLRC4 helical domain HD2 Cullin_binding PF03556.15 GBG72771.1 - 3.7e-31 108.1 0.1 6.1e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 Cullin binding DUF326 PF03860.16 GBG72771.1 - 1.8 8.7 5.8 3.4 7.8 5.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) zf-C2H2 PF00096.26 GBG72772.1 - 7.7e-08 32.4 7.6 0.014 15.8 0.3 4.0 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GBG72772.1 - 5.7e-06 26.5 5.9 0.00042 20.5 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GBG72772.1 - 9.5e-05 22.3 4.2 0.094 12.7 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GBG72772.1 - 0.0038 17.9 13.8 0.43 11.5 0.2 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 GBG72772.1 - 0.0051 17.2 3.9 0.016 15.6 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type TFIIA PF03153.13 GBG72772.1 - 0.04 13.9 21.6 0.078 13.0 21.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 GBG72772.1 - 0.12 11.9 8.2 0.19 11.3 8.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pex14_N PF04695.13 GBG72772.1 - 0.54 10.9 13.9 0.057 14.1 6.4 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 GBG72772.1 - 2 7.3 6.1 3 6.7 6.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 GBG72772.1 - 4 8.5 8.6 13 6.8 8.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 GBG72772.1 - 4.1 7.4 4.4 9.9 6.1 4.4 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 GBG72772.1 - 5 7.0 8.0 9 6.2 8.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-H2C2_2 PF13465.6 GBG72772.1 - 7.3 7.2 17.8 0.75 10.3 6.6 3.6 3 0 0 3 3 3 0 Zinc-finger double domain DUF3807 PF12720.7 GBG72773.1 - 0.38 11.0 10.2 0.73 10.1 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SDA1 PF05285.12 GBG72773.1 - 2.9 7.2 21.5 6.1 6.2 21.5 1.4 1 0 0 1 1 1 0 SDA1 Myb_DNA-bind_4 PF13837.6 GBG72774.1 - 6.5e-09 36.1 0.5 6.5e-09 36.1 0.5 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72774.1 - 0.026 14.8 0.2 0.068 13.5 0.2 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG72774.1 - 0.061 13.4 0.5 0.15 12.1 0.5 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Kelch_1 PF01344.25 GBG72775.1 - 4.3e-47 157.5 9.4 2e-10 40.0 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 GBG72775.1 - 6.6e-42 141.3 0.9 7.3e-09 35.5 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GBG72775.1 - 8.8e-38 127.4 0.6 1.7e-09 37.6 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GBG72775.1 - 1.4e-35 120.9 5.5 5.1e-10 39.4 0.0 7.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 GBG72775.1 - 1.3e-28 97.9 7.2 4.4e-06 26.5 0.0 6.9 7 0 0 7 7 6 6 Kelch motif Kelch_5 PF13854.6 GBG72775.1 - 1.9e-26 91.6 10.9 1.8e-06 27.8 0.0 7.1 7 0 0 7 7 7 6 Kelch motif RVT_1 PF00078.27 GBG72775.1 - 7.4e-25 87.8 0.0 1.3e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTB PF00651.31 GBG72775.1 - 1.2e-23 83.4 0.4 3e-23 82.2 0.4 1.6 1 0 0 1 1 1 1 BTB/POZ domain RT_RNaseH PF17917.1 GBG72775.1 - 7.6e-20 71.2 0.2 3e-18 66.0 0.1 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72775.1 - 4.8e-17 61.8 0.9 2.9e-16 59.3 0.7 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG72775.1 - 1.2e-12 47.7 0.0 1.1e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72775.1 - 6.4e-09 36.0 0.1 2.7e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Skp1_POZ PF03931.15 GBG72775.1 - 0.014 15.5 0.0 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain BACK PF07707.15 GBG72775.1 - 0.14 12.3 0.3 8.1 6.6 0.0 2.9 2 0 0 2 2 2 0 BTB And C-terminal Kelch Aldedh PF00171.22 GBG72776.1 - 0.11 11.0 0.6 5.7 5.3 0.1 2.1 2 0 0 2 2 2 0 Aldehyde dehydrogenase family DUF305 PF03713.13 GBG72776.1 - 1.4 9.0 3.5 24 5.0 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF305) THEG PF14912.6 GBG72776.1 - 2.8 8.5 4.9 23 5.6 0.2 2.9 3 0 0 3 3 3 0 Testicular haploid expressed repeat zf-C3HC4_5 PF17121.5 GBG72777.1 - 0.019 14.9 0.2 0.067 13.1 0.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Auts2 PF15336.6 GBG72779.1 - 0.17 12.0 1.0 0.21 11.7 1.0 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Herpes_capsid PF06112.11 GBG72779.1 - 0.88 9.6 5.8 1.2 9.2 5.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AGO_N PF18236.1 GBG72780.1 - 0.55 10.5 2.9 1 9.6 0.0 2.7 1 1 0 2 2 2 0 Argonaute N domain DUF922 PF06037.11 GBG72780.1 - 1.5 8.6 7.8 0.29 10.9 2.4 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF922) TruB_C_2 PF16198.5 GBG72780.1 - 8.3 6.6 6.9 1.4 9.1 0.2 3.1 4 0 0 4 4 4 0 tRNA pseudouridylate synthase B C-terminal domain DUF659 PF04937.15 GBG72781.1 - 4.5e-24 85.0 0.0 9.3e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG72781.1 - 2.8e-05 23.8 0.1 5.8e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG72783.1 - 1.4e-07 32.0 0.0 3.9e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72783.1 - 0.00021 21.9 0.0 0.00053 20.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG72783.1 - 0.0022 17.8 0.3 0.0039 17.0 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG72783.1 - 0.035 14.4 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG72783.1 - 0.046 14.0 0.3 0.25 11.6 0.1 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein RPOL_N PF14700.6 GBG72784.1 - 0.093 12.1 7.3 0.14 11.5 7.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Connexin PF00029.19 GBG72784.1 - 0.36 10.6 3.0 0.68 9.7 3.0 1.4 1 0 0 1 1 1 0 Connexin DUF1682 PF07946.14 GBG72784.1 - 0.69 9.1 19.5 1.5 8.0 19.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NARP1 PF12569.8 GBG72784.1 - 0.7 8.7 13.0 1.3 7.9 13.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Protocadherin PF08374.11 GBG72784.1 - 0.77 9.7 3.7 1.3 8.9 3.7 1.4 1 0 0 1 1 1 0 Protocadherin DUF2514 PF10721.9 GBG72784.1 - 4.8 7.2 15.7 11 6.0 15.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) TcdA_TcdB PF12919.7 GBG72785.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Folate_rec PF03024.14 GBG72786.1 - 1.4e-15 57.6 0.4 1.9e-15 57.1 0.4 1.2 1 0 0 1 1 1 1 Folate receptor family Cwf_Cwc_15 PF04889.12 GBG72787.1 - 5.3 6.7 10.4 6.1 6.5 1.6 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Radial_spoke_3 PF06098.11 GBG72788.1 - 0.00025 20.4 11.2 0.00025 20.4 11.2 1.7 2 0 0 2 2 2 1 Radial spoke protein 3 PhoU PF01895.19 GBG72788.1 - 0.002 18.5 3.3 0.47 10.9 0.1 3.0 3 0 0 3 3 3 2 PhoU domain ZapB PF06005.12 GBG72788.1 - 0.0068 16.8 23.9 0.091 13.2 0.0 3.5 3 0 0 3 3 3 2 Cell division protein ZapB DivIC PF04977.15 GBG72788.1 - 0.11 12.3 0.1 0.11 12.3 0.1 3.7 3 0 0 3 3 3 0 Septum formation initiator Casc1_N PF15927.5 GBG72788.1 - 0.12 12.0 17.6 0.5 10.0 17.6 2.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus U79_P34 PF03064.16 GBG72788.1 - 0.16 11.3 10.7 0.36 10.2 10.7 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Afaf PF15339.6 GBG72788.1 - 1.8 8.2 5.6 1.8 8.3 2.1 2.1 2 0 0 2 2 2 0 Acrosome formation-associated factor Connexin PF00029.19 GBG72788.1 - 9.4 5.9 7.6 18 5.0 7.6 1.4 1 0 0 1 1 1 0 Connexin Atrophin-1 PF03154.15 GBG72789.1 - 6.4 4.9 18.4 13 3.9 18.4 1.5 1 0 0 1 1 1 0 Atrophin-1 family SAPS PF04499.15 GBG72789.1 - 6.6 5.4 11.3 8.7 5.0 11.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Retrotrans_gag PF03732.17 GBG72792.1 - 0.0041 17.4 7.4 0.01 16.1 0.0 3.6 3 2 0 3 3 3 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG72792.1 - 0.029 13.7 12.3 0.021 14.2 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 GBG72792.1 - 0.061 13.8 1.2 0.47 11.0 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CPG4 PF15481.6 GBG72792.1 - 0.12 13.0 1.0 16 6.2 0.2 2.5 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 M PF02370.16 GBG72792.1 - 1.7 9.5 7.4 0.96 10.2 1.8 3.1 2 0 0 2 2 2 0 M protein repeat ADIP PF11559.8 GBG72792.1 - 2.3 8.3 15.2 0.38 10.8 1.4 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Scaffolding_pro PF11418.8 GBG72792.1 - 6.4 7.4 6.3 30 5.3 0.1 3.0 3 1 0 3 3 3 0 Phi29 scaffolding protein ESM4 PF15952.5 GBG72793.1 - 0.009 16.5 1.1 0.018 15.5 1.1 1.4 1 0 0 1 1 1 1 Enhancer of split M4 family BAR PF03114.18 GBG72794.1 - 2.3 7.8 8.7 3.8 7.1 8.7 1.3 1 0 0 1 1 1 0 BAR domain Dimer_Tnp_hAT PF05699.14 GBG72798.1 - 5.6e-05 22.9 0.0 9.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SoxY PF13501.6 GBG72799.1 - 0.044 14.0 0.5 3 8.1 0.0 2.2 1 1 0 2 2 2 0 Sulfur oxidation protein SoxY DUF963 PF06131.11 GBG72799.1 - 1.2 8.6 6.6 23 4.5 6.6 2.8 1 1 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) MDMPI_C PF07398.11 GBG72800.1 - 0.029 15.2 0.2 0.067 14.1 0.2 1.6 1 0 0 1 1 1 0 MDMPI C-terminal domain DEAD PF00270.29 GBG72803.1 - 2e-46 157.9 0.0 3.4e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG72803.1 - 3e-30 104.8 0.0 7e-29 100.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GBG72803.1 - 0.002 17.4 0.0 0.002 17.4 0.0 2.9 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 GBG72803.1 - 0.05 12.4 0.0 0.12 11.1 0.0 1.7 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 GBG72803.1 - 0.22 10.8 0.0 0.22 10.8 0.0 5.4 6 0 0 6 6 6 0 U3-containing 90S pre-ribosomal complex subunit RVT_1 PF00078.27 GBG72804.1 - 5.5e-29 101.3 0.0 1e-28 100.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72804.1 - 3e-22 78.5 0.0 6e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72804.1 - 4.1e-20 72.0 0.0 7.9e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG72804.1 - 2.6e-07 31.2 0.0 5.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72804.1 - 2.8e-06 27.8 0.0 5.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG72804.1 - 7.5e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72804.1 - 0.0037 17.1 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG72804.1 - 0.1 12.9 0.0 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain SHMT PF00464.19 GBG72805.1 - 1.1e-192 640.0 0.0 1.3e-192 639.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF4972 PF16342.5 GBG72806.1 - 0.078 12.7 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) Snf7 PF03357.21 GBG72806.1 - 0.13 11.8 3.8 0.24 11.0 0.2 2.3 2 0 0 2 2 2 0 Snf7 DUF4972 PF16342.5 GBG72807.1 - 0.1 12.3 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) FA_desaturase PF00487.24 GBG72807.1 - 0.1 12.4 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Snf7 PF03357.21 GBG72807.1 - 0.17 11.4 3.7 0.28 10.8 0.2 2.3 2 0 0 2 2 2 0 Snf7 HNH_3 PF13392.6 GBG72808.1 - 0.11 12.3 3.7 3.7 7.4 0.1 2.4 2 1 1 3 3 3 0 HNH endonuclease ACCA PF03255.14 GBG72808.1 - 0.25 11.2 1.1 1.4 8.8 0.5 1.9 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FANCI_S4 PF14678.6 GBG72809.1 - 2.3e-47 161.2 0.0 4.8e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 FANCI solenoid 4 FANCI_HD2 PF14680.6 GBG72809.1 - 3.1e-37 128.1 0.0 6.8e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_S2 PF14676.6 GBG72809.1 - 7.4e-35 120.7 0.1 2.8e-34 118.8 0.0 2.1 2 0 0 2 2 2 1 FANCI solenoid 2 FANCI_S1 PF14675.6 GBG72809.1 - 2.8e-19 69.6 0.2 3.6e-16 59.4 0.0 3.6 4 0 0 4 4 4 1 FANCI solenoid 1 FANCI_HD1 PF14679.6 GBG72809.1 - 3.1e-18 65.5 2.8 2.6e-17 62.6 0.2 3.5 4 0 0 4 4 4 1 FANCI helical domain 1 DUF3301 PF11743.8 GBG72809.1 - 0.17 11.6 0.5 0.57 9.9 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) RhoGAP PF00620.27 GBG72810.1 - 8.8e-31 106.8 0.0 1.6e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain ApoLp-III PF07464.11 GBG72810.1 - 0.19 11.8 3.4 0.34 11.0 3.4 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Metallophos PF00149.28 GBG72812.1 - 1.8e-22 80.9 0.3 2.9e-22 80.2 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GBG72812.1 - 2e-13 50.7 0.1 4.4e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 GBG72812.1 - 1.3e-06 28.7 0.0 6.7e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EB1 PF03271.17 GBG72813.1 - 1.6e-19 69.8 0.3 3.5e-19 68.8 0.3 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 GBG72813.1 - 5.3e-10 39.5 1.8 5.6e-10 39.4 0.1 1.9 2 1 1 3 3 3 1 Calponin homology (CH) domain CH_2 PF06294.11 GBG72813.1 - 8.9e-06 25.7 0.1 1.9e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein FlxA PF14282.6 GBG72813.1 - 0.016 15.2 0.3 0.016 15.2 0.3 2.4 2 1 0 2 2 1 0 FlxA-like protein CAMSAP_CH PF11971.8 GBG72813.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain NEMO PF11577.8 GBG72813.1 - 0.086 12.9 0.8 0.17 11.9 0.8 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Tmemb_cc2 PF10267.9 GBG72813.1 - 0.1 11.7 3.4 0.13 11.4 3.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GIT_CC PF16559.5 GBG72813.1 - 0.15 11.9 3.2 0.15 11.9 1.3 1.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_N PF10481.9 GBG72813.1 - 0.24 11.0 6.5 0.37 10.4 6.5 1.3 1 0 0 1 1 1 0 Cenp-F N-terminal domain NAM-associated PF14303.6 GBG72813.1 - 0.29 11.9 6.6 0.46 11.2 6.6 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain HALZ PF02183.18 GBG72813.1 - 0.48 10.7 5.0 0.75 10.1 2.6 2.5 2 1 1 3 3 3 0 Homeobox associated leucine zipper FAM199X PF15814.5 GBG72813.1 - 0.56 9.2 10.3 0.77 8.8 10.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X AUX_IAA PF02309.16 GBG72813.1 - 0.67 9.8 6.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 AUX/IAA family SR-25 PF10500.9 GBG72813.1 - 0.93 9.1 14.5 2 8.0 14.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Use1 PF09753.9 GBG72813.1 - 1.2 8.8 6.3 1.9 8.1 6.3 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 bZIP_1 PF00170.21 GBG72813.1 - 1.4 9.1 4.4 0.73 10.0 1.7 1.9 2 0 0 2 2 2 0 bZIP transcription factor RAP1 PF07218.11 GBG72813.1 - 3 6.0 7.2 4 5.6 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ATG16 PF08614.11 GBG72813.1 - 5.5 7.2 10.7 1.3 9.2 7.5 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PIG-P PF08510.12 GBG72815.1 - 1.1e-34 118.9 2.0 1.8e-34 118.3 2.0 1.3 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 GBG72815.1 - 0.017 15.4 9.0 0.042 14.2 9.0 1.5 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) E1-E2_ATPase PF00122.20 GBG72815.1 - 0.29 10.6 0.7 0.48 9.9 0.7 1.3 1 0 0 1 1 1 0 E1-E2 ATPase SDA1 PF05285.12 GBG72815.1 - 9 5.6 29.7 0.17 11.3 22.8 1.6 2 0 0 2 2 2 0 SDA1 TPR_1 PF00515.28 GBG72816.1 - 1.7e-16 59.2 5.6 2.7e-06 26.9 0.0 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG72816.1 - 5.7e-15 54.1 7.5 3.4e-05 23.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG72816.1 - 2.1e-10 40.1 3.2 0.012 15.3 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_9 PF13371.6 GBG72816.1 - 1.1e-08 35.1 3.1 2.4e-06 27.6 1.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG72816.1 - 1.2e-08 34.5 0.9 0.00017 21.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG72816.1 - 4.1e-08 33.7 0.7 0.00035 21.2 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG72816.1 - 2.2e-06 27.9 4.8 0.00035 20.8 0.9 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG72816.1 - 1.3e-05 25.6 7.9 0.00036 21.0 4.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG72816.1 - 6.4e-05 23.5 4.0 0.0043 17.7 0.4 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG72816.1 - 0.00012 22.3 2.5 0.0062 16.8 0.2 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GBG72816.1 - 0.00031 21.2 1.5 0.047 14.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG72816.1 - 0.005 16.8 2.4 6.6 7.0 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 GBG72816.1 - 0.0059 15.9 3.4 0.015 14.5 1.7 2.0 1 1 0 2 2 2 1 Tetratricopeptide repeat OSCP PF00213.18 GBG72816.1 - 0.015 15.5 1.0 0.022 14.9 0.1 1.8 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit SPT16 PF08644.11 GBG72816.1 - 0.015 15.5 0.4 0.026 14.7 0.4 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Fis1_TPR_C PF14853.6 GBG72816.1 - 0.017 15.2 1.7 0.28 11.3 0.0 3.0 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 GBG72816.1 - 0.14 12.1 1.4 16 5.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 GBG72816.1 - 0.16 12.0 3.5 1 9.5 1.4 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 GBG72816.1 - 3 8.0 8.3 2 8.6 1.0 3.2 1 1 2 3 3 3 0 MIT (microtubule interacting and transport) domain Myb_DNA-bind_4 PF13837.6 GBG72818.1 - 0.4 11.1 3.4 0.3 11.5 0.7 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain IPPT PF01715.17 GBG72819.1 - 1.4e-50 172.2 0.0 2.2e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 IPP transferase dCMP_cyt_deam_1 PF00383.23 GBG72819.1 - 4.1e-18 65.1 0.1 1.1e-17 63.8 0.1 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GBG72819.1 - 2.1e-10 40.5 0.0 4.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase RibD_C PF01872.17 GBG72819.1 - 2.3e-10 40.6 0.2 7.2e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 RibD C-terminal domain IPT PF01745.16 GBG72819.1 - 8.7e-08 31.8 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase AAA_18 PF13238.6 GBG72819.1 - 0.0002 21.9 0.8 0.00099 19.7 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 GBG72819.1 - 0.0015 18.7 0.0 0.0046 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG72819.1 - 0.0026 18.1 0.0 0.01 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Hpr_kinase_C PF07475.12 GBG72819.1 - 0.0083 15.7 0.2 0.018 14.6 0.2 1.5 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 GBG72819.1 - 0.0088 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 GBG72819.1 - 0.0098 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GBG72819.1 - 0.015 15.7 0.1 0.039 14.4 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 GBG72819.1 - 0.017 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 GBG72819.1 - 0.027 14.2 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 GBG72819.1 - 0.039 13.9 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 GBG72819.1 - 0.044 13.0 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin PF02224.18 GBG72819.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 GBG72819.1 - 0.061 13.3 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GBG72819.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 GBG72819.1 - 0.27 10.7 0.7 0.49 9.8 0.2 1.6 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase AAA_28 PF13521.6 GBG72819.1 - 7.1 6.8 5.8 1.4 9.1 0.1 2.8 3 1 1 4 4 3 0 AAA domain Esterase PF00756.20 GBG72820.1 - 2.3e-61 207.6 0.0 2.7e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 GBG72820.1 - 2.1e-08 33.9 0.1 3.1e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 GBG72820.1 - 0.00014 21.5 0.0 0.0015 18.1 0.0 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 GBG72820.1 - 0.00022 20.6 0.0 0.00075 18.8 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 GBG72820.1 - 0.00049 19.7 0.3 0.004 16.7 0.1 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 GBG72820.1 - 0.0018 17.3 0.0 0.0037 16.2 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 GBG72820.1 - 0.0039 15.8 0.0 0.0073 14.9 0.0 1.3 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 GBG72820.1 - 0.0061 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.16 GBG72820.1 - 0.042 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 GBG72820.1 - 0.091 11.4 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) SR-25 PF10500.9 GBG72821.1 - 0.00054 19.6 19.7 0.00054 19.6 19.7 4.0 4 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein Miga PF10265.9 GBG72821.1 - 0.073 12.0 3.9 0.19 10.7 3.9 1.6 1 0 0 1 1 1 0 Mitoguardin DUF3446 PF11928.8 GBG72821.1 - 0.35 11.2 24.1 2.6 8.4 19.7 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF659 PF04937.15 GBG72822.1 - 7.2e-15 55.2 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) YL1 PF05764.13 GBG72822.1 - 4.2 7.4 12.4 1.1 9.4 1.4 2.4 2 1 0 2 2 2 0 YL1 nuclear protein Chlam_PMP PF02415.17 GBG72823.1 - 0.28 11.7 23.5 7.3 7.3 2.7 6.1 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RVT_1 PF00078.27 GBG72824.1 - 0.028 13.9 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG72825.1 - 1.1e-30 106.9 0.0 2.3e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C48 PF02902.19 GBG72825.1 - 1.4e-22 80.7 0.1 2.3e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Chromo PF00385.24 GBG72826.1 - 1.3e-12 47.4 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG72826.1 - 8.4e-09 35.6 0.0 2.6e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Thioredoxin_6 PF13848.6 GBG72828.1 - 6.5e-13 49.0 0.2 9.6e-09 35.4 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 GBG72828.1 - 7e-09 35.6 0.0 0.00083 19.3 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Histone PF00125.24 GBG72829.1 - 4.2e-24 85.4 0.3 4.2e-24 85.4 0.3 3.6 3 1 1 4 4 4 1 Core histone H2A/H2B/H3/H4 Plavaka PF18759.1 GBG72829.1 - 5.8e-18 65.2 0.1 1.2e-17 64.2 0.1 1.4 1 0 0 1 1 1 1 Plavaka transposase TFIIA PF03153.13 GBG72829.1 - 0.37 10.7 23.9 0.024 14.7 14.0 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 GBG72830.1 - 1.3e-25 90.3 0.6 1.3e-25 90.3 0.6 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Plavaka PF18759.1 GBG72830.1 - 6.6e-12 45.3 0.1 1.2e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase Chlam_PMP PF02415.17 GBG72831.1 - 4.5e-05 23.7 24.7 1.4 9.6 1.9 6.4 6 0 0 6 6 6 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 GBG72831.1 - 0.0001 22.2 11.9 0.0011 18.8 0.5 2.2 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 GBG72831.1 - 0.029 13.6 1.4 0.043 13.1 1.4 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Zwilch PF09817.9 GBG72832.1 - 0.14 10.6 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 RZZ complex, subunit zwilch DUF659 PF04937.15 GBG72834.1 - 2.9e-17 62.9 0.0 4.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Lysine_decarbox PF03641.14 GBG72837.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Possible lysine decarboxylase Chlam_PMP PF02415.17 GBG72837.1 - 0.47 11.1 24.2 13 6.5 0.9 6.3 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF1664 PF07889.12 GBG72838.1 - 0.015 15.3 5.2 0.031 14.3 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5069 PF16798.5 GBG72838.1 - 0.016 15.4 0.5 0.5 10.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) PEP-utilisers_N PF05524.13 GBG72838.1 - 0.062 13.5 5.9 0.072 13.3 4.6 1.8 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Nsp1_C PF05064.13 GBG72838.1 - 0.15 11.9 4.4 0.4 10.5 0.8 2.8 2 2 0 2 2 2 0 Nsp1-like C-terminal region FAP206 PF12018.8 GBG72838.1 - 0.19 11.2 4.7 0.29 10.6 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function ADIP PF11559.8 GBG72838.1 - 2.5 8.1 13.8 4.7 7.3 13.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-CCHC PF00098.23 GBG72839.1 - 0.0022 18.0 0.6 0.0054 16.8 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG72839.1 - 0.01 15.6 0.8 0.021 14.6 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle BDV_P10 PF06515.11 GBG72839.1 - 0.011 15.8 0.7 2.1 8.5 0.2 2.9 2 0 0 2 2 2 0 Borna disease virus P10 protein RVT_1 PF00078.27 GBG72841.1 - 3.5e-20 72.5 0.2 5.9e-20 71.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72841.1 - 1.9e-08 34.3 0.0 4.9e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72841.1 - 6.1e-05 23.2 0.1 0.00025 21.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG72849.1 - 1.2e-28 99.1 0.0 2e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72849.1 - 4.8e-27 94.3 0.0 7.8e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72849.1 - 2.6e-14 53.3 0.0 3.6e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG72849.1 - 0.71 10.1 14.4 1.1 9.5 14.4 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated CobT PF06213.12 GBG72849.1 - 1.7 7.9 19.9 3 7.2 19.9 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 GBG72849.1 - 2.3 6.3 24.9 3.3 5.8 24.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG72849.1 - 2.5 7.4 26.4 3.4 7.0 26.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG72849.1 - 3.9 5.7 17.4 6.3 5.0 17.4 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG72849.1 - 4.7 6.4 27.0 6.9 5.9 27.0 1.1 1 0 0 1 1 1 0 BUD22 SURF2 PF05477.11 GBG72849.1 - 9.1 5.9 11.3 16 5.0 11.3 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ACT PF01842.25 GBG72856.1 - 1.6e-11 43.8 0.0 0.00024 20.8 0.1 3.6 3 0 0 3 3 3 3 ACT domain ACT_4 PF13291.6 GBG72856.1 - 8.1e-11 42.4 0.0 0.0027 18.3 0.0 3.4 3 0 0 3 3 3 3 ACT domain ACT_6 PF13740.6 GBG72856.1 - 5.2e-08 32.8 0.6 9e-06 25.6 0.1 2.6 2 0 0 2 2 2 2 ACT domain DUF1247 PF06851.11 GBG72856.1 - 0.084 12.8 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) ArenaCapSnatch PF17296.2 GBG72856.1 - 0.13 11.7 0.1 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Arenavirus cap snatching domain DUF883 PF05957.13 GBG72857.1 - 0.015 15.9 1.0 0.015 15.9 1.0 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SOAR PF16533.5 GBG72857.1 - 0.23 11.5 5.6 0.11 12.5 1.6 2.5 2 0 0 2 2 2 0 STIM1 Orai1-activating region gag-asp_proteas PF13975.6 GBG72858.1 - 4.2e-19 68.9 0.1 3.2e-05 24.4 0.0 3.8 3 0 0 3 3 3 3 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72858.1 - 4.3e-13 49.7 0.1 0.0015 19.2 0.0 3.8 4 0 0 4 4 4 3 Aspartyl protease RVT_1 PF00078.27 GBG72858.1 - 1.9e-08 34.1 0.0 3.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 GBG72858.1 - 1.1e-07 32.1 0.1 0.47 10.8 0.0 3.6 3 0 0 3 3 3 3 Retroviral aspartyl protease Asp_protease PF09668.10 GBG72858.1 - 2.5e-07 30.5 15.3 0.016 15.0 1.5 3.4 3 0 0 3 3 3 3 Aspartyl protease DUF4379 PF14311.6 GBG72858.1 - 0.0015 18.8 3.9 17 5.9 0.3 3.8 3 0 0 3 3 3 3 Probable Zinc-ribbon domain Peptidase_A2E PF12382.8 GBG72858.1 - 0.0055 16.7 0.1 15 5.6 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon peptidase WAK PF08488.11 GBG72858.1 - 0.01 16.3 0.2 6.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Wall-associated kinase Zn_ribbon_SprT PF17283.2 GBG72858.1 - 0.058 13.3 6.9 12 5.9 0.2 3.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF4922 PF16269.5 GBG72860.1 - 6.4e-09 35.9 0.0 9.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) Band_7 PF01145.25 GBG72862.1 - 2.7e-11 43.8 0.8 2.7e-11 43.8 0.8 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family Alba PF01918.21 GBG72863.1 - 7.1e-13 48.2 0.9 9.3e-13 47.8 0.3 1.5 2 0 0 2 2 2 1 Alba Rpp20 PF12328.8 GBG72863.1 - 0.00017 21.6 1.1 0.00021 21.2 1.1 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P OsmC PF02566.19 GBG72863.1 - 0.022 15.2 0.2 0.034 14.6 0.2 1.2 1 0 0 1 1 1 0 OsmC-like protein Sybindin PF04099.12 GBG72864.1 - 2.5e-20 72.9 0.0 3.8e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Phi-29_GP3 PF05435.11 GBG72865.1 - 0.012 15.1 2.4 0.012 15.1 2.4 1.9 2 0 0 2 2 2 0 Phi-29 DNA terminal protein GP3 Trypan_PARP PF05887.11 GBG72865.1 - 0.012 15.6 2.8 0.012 15.6 2.8 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) HTH_17 PF12728.7 GBG72865.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Cytochrom_C1 PF02167.15 GBG72865.1 - 0.11 12.3 1.2 0.19 11.4 1.2 1.4 1 0 0 1 1 1 0 Cytochrome C1 family Bacillus_HBL PF05791.11 GBG72865.1 - 0.42 10.4 13.4 0.61 9.9 7.2 2.7 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Kelch_1 PF01344.25 GBG72867.1 - 3.7e-35 119.3 0.1 2e-13 49.7 0.0 3.1 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 GBG72867.1 - 1.6e-30 104.3 1.1 6.8e-10 38.9 0.0 3.1 1 1 2 3 3 3 3 Kelch motif Kelch_4 PF13418.6 GBG72867.1 - 3.6e-20 71.7 6.0 4.7e-08 32.9 0.1 3.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GBG72867.1 - 1.5e-17 62.8 0.2 0.0003 20.6 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 GBG72867.1 - 4.6e-17 61.8 1.1 6.5e-07 29.5 0.1 3.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG72867.1 - 1.7e-16 59.8 1.0 8.1e-05 22.5 0.6 3.3 3 0 0 3 3 3 3 Kelch motif PQQ_3 PF13570.6 GBG72867.1 - 0.11 13.1 4.1 16 6.1 0.3 3.6 4 0 0 4 4 4 0 PQQ-like domain RT_RNaseH PF17917.1 GBG72869.1 - 2.3e-26 92.1 0.0 3.6e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72869.1 - 3e-25 88.2 0.0 5.2e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG72870.1 - 0.00012 22.3 0.1 0.00012 22.3 0.1 3.8 5 1 0 5 5 5 1 Retrotransposon gag protein TAF4 PF05236.14 GBG72870.1 - 0.015 15.0 7.9 0.057 13.2 8.6 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family FAM76 PF16046.5 GBG72870.1 - 0.041 13.3 7.4 0.068 12.5 7.4 1.3 1 0 0 1 1 1 0 FAM76 protein SlyX PF04102.12 GBG72870.1 - 0.099 13.3 0.5 0.099 13.3 0.5 3.9 3 2 0 3 3 3 0 SlyX eIF3_subunit PF08597.10 GBG72870.1 - 1.8 8.4 13.0 3.4 7.5 13.0 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PspB PF06667.12 GBG72870.1 - 2.8 8.0 9.9 11 6.2 0.2 3.3 3 0 0 3 3 3 0 Phage shock protein B DUF4666 PF15697.5 GBG72870.1 - 3.3 8.4 6.3 2 9.2 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) APG6_N PF17675.1 GBG72870.1 - 8.8 6.9 24.6 2.3 8.7 0.8 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region Gpr1_Fun34_YaaH PF01184.19 GBG72871.1 - 5.7e-32 111.0 11.6 6.7e-32 110.8 11.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-RING_2 PF13639.6 GBG72873.1 - 0.00022 21.5 4.2 0.00022 21.5 4.2 7.0 8 0 0 8 8 8 1 Ring finger domain zf-RING_5 PF14634.6 GBG72873.1 - 0.0011 18.9 4.3 0.0011 18.9 4.3 7.2 7 2 1 8 8 8 2 zinc-RING finger domain SelP_C PF04593.14 GBG72874.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, C terminal region TAD2 PF18521.1 GBG72875.1 - 0.29 11.2 2.0 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Transactivation domain 2 Cation_efflux PF01545.21 GBG72877.1 - 5.7e-29 101.3 10.5 7.1e-29 101.0 10.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GBG72877.1 - 7.2e-13 48.5 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter CDC45 PF02724.14 GBG72877.1 - 0.0034 15.7 2.5 0.0047 15.3 2.5 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GBG72877.1 - 1.1 8.6 12.0 1.5 8.2 12.0 1.1 1 0 0 1 1 1 0 SDA1 DUF2516 PF10724.9 GBG72877.1 - 2.1 8.7 5.5 0.49 10.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) zf-CCHC PF00098.23 GBG72878.1 - 6.6e-06 26.0 2.9 1.2e-05 25.1 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG72878.1 - 0.00017 21.3 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72878.1 - 0.00094 19.8 0.1 0.003 18.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72878.1 - 0.0066 17.0 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG72878.1 - 0.027 14.3 3.5 0.045 13.6 3.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 GBG72878.1 - 0.03 14.1 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Cytochrome_CBB3 PF13442.6 GBG72878.1 - 0.076 13.4 1.0 0.15 12.4 1.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF4746 PF15928.5 GBG72878.1 - 0.23 10.9 15.5 0.34 10.3 12.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Inositol_P PF00459.25 GBG72878.1 - 0.23 10.9 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 Inositol monophosphatase family FRQ PF09421.10 GBG72878.1 - 0.49 8.4 4.6 0.68 7.9 4.6 1.1 1 0 0 1 1 1 0 Frequency clock protein Retrotrans_gag PF03732.17 GBG72879.1 - 0.0036 17.5 5.2 0.0037 17.5 0.1 3.4 4 0 0 4 4 4 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG72879.1 - 0.0085 15.9 1.0 0.031 14.0 1.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG72879.1 - 0.071 12.4 7.3 0.15 11.4 7.3 1.5 1 0 0 1 1 1 0 FAM76 protein DUF4666 PF15697.5 GBG72879.1 - 0.43 11.3 6.4 0.29 11.8 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) PIG-L PF02585.17 GBG72880.1 - 3.7e-23 82.6 0.0 1.1e-14 55.2 0.0 2.4 1 1 1 2 2 2 2 GlcNAc-PI de-N-acetylase Ureidogly_lyase PF04115.12 GBG72880.1 - 5.4e-06 26.3 0.0 0.0014 18.4 0.0 2.3 1 1 1 2 2 2 2 Ureidoglycolate lyase Sortilin-Vps10 PF15902.5 GBG72880.1 - 0.068 11.9 0.0 0.16 10.7 0.0 1.5 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, PBP1_TM PF14812.6 GBG72880.1 - 1.7 9.1 10.5 0.057 13.8 2.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DnaJ-X PF14308.6 GBG72881.1 - 0.018 14.5 5.4 0.023 14.1 5.4 1.2 1 0 0 1 1 1 0 X-domain of DnaJ-containing DDRGK PF09756.9 GBG72881.1 - 0.028 14.0 9.9 0.034 13.8 9.9 1.2 1 0 0 1 1 1 0 DDRGK domain GRIM-19 PF06212.12 GBG72881.1 - 0.66 9.9 6.6 1.1 9.2 6.6 1.3 1 0 0 1 1 1 0 GRIM-19 protein MIF4G_like_2 PF09090.11 GBG72881.1 - 0.7 9.3 5.3 0.77 9.2 5.3 1.1 1 0 0 1 1 1 0 MIF4G like V_ATPase_I PF01496.19 GBG72881.1 - 2.1 6.2 5.2 2.4 6.0 5.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mobilization_B PF17511.2 GBG72881.1 - 2.2 8.7 7.7 7.4 6.9 0.4 2.2 1 1 1 2 2 2 0 Mobilization protein B Branch PF02485.21 GBG72883.1 - 1.7e-78 263.6 0.0 2e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Methyltr_RsmB-F PF01189.17 GBG72884.1 - 1.1e-49 168.8 0.0 2.2e-49 167.8 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 GBG72884.1 - 5.3e-17 62.3 0.0 1.2e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 NusB family FtsJ PF01728.19 GBG72884.1 - 8e-09 35.9 0.0 4.8e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.16 GBG72884.1 - 0.00057 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 GBG72884.1 - 0.0011 19.6 0.2 0.0048 17.6 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GBG72884.1 - 0.0054 16.4 0.0 0.049 13.3 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 GBG72884.1 - 0.0059 16.4 0.0 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 GBG72884.1 - 0.007 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase GCD14 PF08704.10 GBG72884.1 - 0.088 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CmcI PF04989.12 GBG72884.1 - 0.15 11.7 0.1 1.1 8.9 0.0 2.3 3 0 0 3 3 3 0 Cephalosporin hydroxylase Lactamase_B_2 PF12706.7 GBG72885.1 - 8.1e-14 51.6 0.0 1.7e-07 31.0 0.0 2.5 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GBG72885.1 - 2.2e-12 47.4 0.1 4.9e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 GBG72885.1 - 4e-08 32.8 0.0 8.7e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease RT_RNaseH PF17917.1 GBG72887.1 - 3.5e-27 94.7 0.1 7.4e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72887.1 - 2.4e-19 69.2 0.0 6.1e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72887.1 - 5.6e-08 33.0 0.0 1.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain TetR_C_15 PF17918.1 GBG72887.1 - 0.073 13.8 0.4 0.22 12.3 0.4 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Jas PF16135.5 GBG72888.1 - 5.3e-08 32.9 0.2 1.2e-07 31.8 0.2 1.6 1 0 0 1 1 1 1 TPL-binding domain in jasmonate signalling HTH_32 PF13565.6 GBG72889.1 - 0.0082 16.7 0.0 0.75 10.5 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain RT_RNaseH PF17917.1 GBG72890.1 - 4.2e-12 46.3 0.0 7.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72890.1 - 0.0015 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG72890.1 - 0.24 9.6 6.2 0.28 9.3 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG72890.1 - 0.56 9.6 8.7 0.74 9.2 8.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG72890.1 - 3.3 5.9 9.5 4.1 5.6 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein rve PF00665.26 GBG72891.1 - 1.1e-15 57.9 0.0 2.7e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG72891.1 - 2.2e-09 37.3 0.0 5.3e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG72891.1 - 1.2e-05 25.5 0.0 0.0001 22.5 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72891.1 - 1.2e-05 24.9 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72891.1 - 4e-05 23.6 0.0 9.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG72891.1 - 0.00071 20.1 0.1 0.0017 18.9 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72891.1 - 0.0021 18.7 0.1 0.0052 17.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 GBG72891.1 - 0.0056 16.4 0.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVP PF00077.20 GBG72891.1 - 0.0078 16.5 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG72891.1 - 0.053 13.8 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4746 PF15928.5 GBG72892.1 - 0.46 9.9 13.0 0.6 9.5 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 GBG72892.1 - 3 7.2 22.0 3.7 6.9 22.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG72892.1 - 3.8 5.7 16.1 4.9 5.3 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG72892.1 - 8.8 4.4 24.3 11 4.0 24.3 1.1 1 0 0 1 1 1 0 Nop14-like family Collagen PF01391.18 GBG72894.1 - 0.00057 19.6 5.1 0.00098 18.8 5.1 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF1187 PF06688.11 GBG72894.1 - 0.0043 17.3 0.4 3.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1187) DUF2742 PF10888.8 GBG72894.1 - 0.21 11.9 2.5 0.77 10.1 0.4 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2742) DBD_HTH PF18430.1 GBG72894.1 - 3 7.7 5.6 6.7 6.6 0.3 2.7 3 0 0 3 3 3 0 Putative DNA-binding domain CENP-B_dimeris PF09026.10 GBG72894.1 - 4.7 7.7 11.3 9.7 6.7 11.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC50 PF03381.15 GBG72895.1 - 1.1e-82 277.8 0.0 1.8e-82 277.0 0.0 1.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Ribosomal_L18p PF00861.22 GBG72897.1 - 6.3e-16 58.8 1.1 9.5e-16 58.2 1.1 1.3 1 1 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast FANCI_S2 PF14676.6 GBG72897.1 - 0.045 14.1 0.1 0.063 13.6 0.1 1.2 1 0 0 1 1 1 0 FANCI solenoid 2 TINF2_N PF14973.6 GBG72897.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Connexin PF00029.19 GBG72898.1 - 0.14 11.9 2.6 0.13 12.1 2.6 1.1 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 GBG72898.1 - 0.14 10.9 1.8 0.13 11.0 1.8 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG72898.1 - 0.28 9.4 11.2 0.29 9.4 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 GBG72898.1 - 0.45 10.6 14.8 0.62 10.1 14.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.12 GBG72898.1 - 0.74 8.0 15.8 0.78 7.9 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 GBG72898.1 - 1.6 7.2 7.3 1.7 7.1 7.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2967 PF11179.8 GBG72898.1 - 3.8 5.5 7.8 3.8 5.5 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF4637 PF15470.6 GBG72898.1 - 5.1 6.8 18.3 8.8 6.0 18.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) V_ATPase_I PF01496.19 GBG72898.1 - 7.1 4.4 5.3 7.4 4.3 5.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 GBG72898.1 - 9.5 6.0 14.5 13 5.5 14.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PC-Esterase PF13839.6 GBG72899.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p RT_RNaseH_2 PF17919.1 GBG72902.1 - 3e-50 168.4 0.0 8.9e-24 83.4 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72902.1 - 7.7e-46 154.7 0.0 8.5e-23 80.6 0.0 3.1 3 0 0 3 3 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72902.1 - 2.6e-17 63.1 0.1 1.1e-16 61.1 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG72902.1 - 3.2e-16 59.6 0.1 7.5e-07 29.4 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG72902.1 - 8.4e-15 54.6 0.6 3.4e-14 52.7 0.2 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG72902.1 - 9.2e-06 26.2 0.0 2.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72902.1 - 1.1e-05 26.0 0.0 2.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG72902.1 - 2.4e-05 24.1 0.0 6.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG72902.1 - 0.00014 22.1 7.5 0.082 13.2 0.1 3.6 3 0 0 3 3 3 2 Retrotransposon gag protein Lipin_mid PF16876.5 GBG72902.1 - 0.00027 21.0 1.3 1.2 9.4 0.0 3.2 3 0 0 3 3 3 2 Lipin/Ned1/Smp2 multi-domain protein middle domain Asp_protease PF09668.10 GBG72902.1 - 0.00053 19.8 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease CDH1_2_SANT_HL1 PF18375.1 GBG72902.1 - 0.0032 18.1 0.1 4.9 7.9 0.0 3.0 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 zf-H2C2 PF09337.10 GBG72902.1 - 0.0068 16.6 0.1 0.018 15.3 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF2497 PF10691.9 GBG72902.1 - 0.17 12.3 1.2 32 5.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) RVT_1 PF00078.27 GBG72903.1 - 9.7e-28 97.2 0.1 1.4e-27 96.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG72903.1 - 0.0033 16.6 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 2 Autophagy protein Apg17 Trypsin PF00089.26 GBG72904.1 - 7.6e-34 117.4 1.4 1e-33 117.0 1.4 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GBG72904.1 - 2.4e-06 28.5 0.1 6.2e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain rve PF00665.26 GBG72905.1 - 0.0026 17.9 0.1 0.0068 16.6 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG72906.1 - 5.5e-24 84.5 0.0 1.1e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72906.1 - 1.1e-22 80.0 0.0 2.1e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG72906.1 - 0.027 15.0 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72906.1 - 0.13 12.9 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease CENP-N PF05238.13 GBG72906.1 - 0.43 9.8 5.2 0.8 8.9 5.2 1.4 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Presenilin PF01080.17 GBG72906.1 - 0.44 9.3 3.0 0.67 8.7 3.0 1.1 1 0 0 1 1 1 0 Presenilin DUF5476 PF17570.2 GBG72907.1 - 0.071 13.5 0.3 0.26 11.7 0.3 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5476) FAM101 PF15068.6 GBG72907.1 - 0.26 11.2 3.1 0.29 11.1 0.9 2.0 1 1 1 2 2 2 0 FAM101 family zf-CCHC PF00098.23 GBG72907.1 - 0.78 9.9 4.8 0.15 12.2 1.0 1.8 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH PF17917.1 GBG72908.1 - 6.8e-24 84.2 0.0 1.4e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72908.1 - 2e-23 82.3 0.0 4.6e-23 81.1 0.0 1.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Drf_GBD PF06371.13 GBG72908.1 - 0.23 11.0 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain RT_RNaseH PF17917.1 GBG72909.1 - 5.2e-24 84.5 0.0 1.1e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72909.1 - 1.1e-19 70.2 0.2 2.5e-19 69.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG72909.1 - 6.5e-17 61.4 0.0 1.4e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG72909.1 - 2e-09 37.3 0.0 3.6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG72909.1 - 1.9e-08 34.5 0.1 9.3e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG72909.1 - 4.1e-08 33.7 0.0 7.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72909.1 - 2.3e-07 31.3 0.0 4.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG72909.1 - 0.0072 16.5 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG72909.1 - 0.027 14.3 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG72909.1 - 0.063 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG72910.1 - 4.9e-21 75.0 0.0 1.1e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72910.1 - 3.1e-20 72.1 0.0 6.7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nucleo_P87 PF07267.11 GBG72910.1 - 0.54 9.0 2.5 0.81 8.5 2.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-CCHC PF00098.23 GBG72911.1 - 8.6e-09 35.1 2.6 1.6e-08 34.2 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG72911.1 - 0.00025 21.0 0.7 0.00086 19.2 0.7 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG72911.1 - 0.017 14.8 1.1 0.04 13.7 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG72911.1 - 0.03 14.2 1.7 0.081 12.8 1.7 1.8 1 0 0 1 1 1 0 Zinc knuckle Trimer_CC PF08954.11 GBG72911.1 - 0.036 13.6 0.4 0.036 13.6 0.4 4.3 3 1 1 4 4 4 0 Trimerisation motif zf-CCHC_2 PF13696.6 GBG72911.1 - 0.1 12.4 3.9 0.2 11.5 3.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Shugoshin_N PF07558.11 GBG72911.1 - 0.45 10.4 5.2 0.29 11.1 1.3 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Gal-3-0_sulfotr PF06990.11 GBG72911.1 - 0.47 9.3 1.8 6.4 5.5 0.2 2.3 2 0 0 2 2 2 0 Galactose-3-O-sulfotransferase SpoOE-like PF09388.10 GBG72911.1 - 5 7.1 11.8 0.35 10.8 2.1 3.4 4 0 0 4 4 4 0 Spo0E like sporulation regulatory protein RVT_1 PF00078.27 GBG72912.1 - 5.4e-25 88.2 0.6 1.8e-24 86.5 0.3 2.0 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72912.1 - 3.8e-20 71.8 0.0 6.8e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72912.1 - 9.3e-20 70.9 0.1 2.4e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72912.1 - 1.9e-16 59.9 0.9 4.8e-16 58.6 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG72913.1 - 6.9e-28 97.7 0.0 5.2e-24 85.0 0.1 4.1 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72913.1 - 1.4e-21 76.3 0.0 3.4e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72913.1 - 2.5e-21 75.9 0.0 6.2e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72913.1 - 1.6e-19 69.7 0.1 5.8e-19 68.0 0.1 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG72913.1 - 1.7e-08 34.4 0.0 1e-06 28.6 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease rve PF00665.26 GBG72913.1 - 4.9e-08 33.2 0.0 2.4e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG72913.1 - 1.4e-05 25.7 0.0 4.4e-05 24.0 0.0 1.9 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72913.1 - 0.00036 21.0 0.0 0.0008 19.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG72913.1 - 0.011 16.0 0.0 0.055 13.7 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG72913.1 - 0.03 14.5 0.2 0.52 10.6 0.0 2.9 2 0 0 2 2 2 0 H2C2 zinc finger Asp_protease PF09668.10 GBG72913.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG72914.1 - 1.7e-18 66.5 0.4 3e-18 65.7 0.4 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72914.1 - 5.4e-12 46.0 0.0 1.2e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG72914.1 - 7.7e-06 26.4 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG72914.1 - 0.00044 20.0 0.0 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72914.1 - 0.0014 19.2 0.0 0.0032 18.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG72914.1 - 0.043 14.0 0.0 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DUF1758 PF05585.12 GBG72914.1 - 0.094 12.5 0.0 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 Putative peptidase (DUF1758) DUF1564 PF07600.11 GBG72914.1 - 0.11 12.2 0.1 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG72915.1 - 8.4e-33 113.7 0.1 1.4e-32 113.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72915.1 - 1.5e-30 105.2 0.0 2.8e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72915.1 - 3.4e-27 94.8 0.1 7e-27 93.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rab3-GTPase_cat PF13890.6 GBG72915.1 - 0.13 11.9 2.5 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit MREG PF15812.5 GBG72916.1 - 0.00047 20.5 14.7 0.067 13.5 2.4 2.6 2 1 0 2 2 2 2 Melanoregulin Flavodoxin_3 PF12641.7 GBG72916.1 - 0.062 13.0 2.4 0.18 11.5 2.4 1.7 1 0 0 1 1 1 0 Flavodoxin domain RT_RNaseH_2 PF17919.1 GBG72918.1 - 4.2e-35 119.8 0.0 1.1e-34 118.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72918.1 - 3.1e-29 101.3 0.2 1.4e-28 99.2 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72918.1 - 3.4e-08 33.3 0.0 6.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG72918.1 - 2.2e-06 27.5 0.0 7.7e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72918.1 - 0.00017 22.1 0.0 0.0061 17.2 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72918.1 - 0.0072 16.9 0.0 0.098 13.2 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotran_gag_2 PF14223.6 GBG72918.1 - 0.029 14.0 0.1 3.8 7.2 0.0 3.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Phage_GPO PF05929.11 GBG72918.1 - 0.12 11.9 1.9 17 4.9 0.0 2.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase CENP-Q PF13094.6 GBG72918.1 - 0.22 11.7 6.6 0.28 11.4 4.8 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RVT_1 PF00078.27 GBG72919.1 - 2.3e-60 203.9 0.8 7.4e-31 107.4 0.1 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72919.1 - 2e-28 98.3 0.0 5.8e-28 96.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72919.1 - 1.9e-26 92.4 0.1 5.4e-26 90.9 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG72919.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Drf_DAD PF06345.11 GBG72920.1 - 0.035 14.1 1.2 0.098 12.7 1.2 1.8 1 0 0 1 1 1 0 DRF Autoregulatory Domain RVT_1 PF00078.27 GBG72921.1 - 2.5e-34 118.7 0.0 4.8e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72921.1 - 1.8e-17 63.2 0.0 3.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72921.1 - 1.8e-05 25.0 0.0 3.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Terminase_4 PF05119.12 GBG72921.1 - 0.037 14.4 0.5 6.7 7.2 0.1 2.7 2 0 0 2 2 2 0 Phage terminase, small subunit RT_RNaseH PF17917.1 GBG72922.1 - 1.5e-11 44.5 0.0 4e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72922.1 - 1.5e-10 41.0 0.6 2.7e-10 40.2 0.1 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72923.1 - 1.5e-17 63.9 0.0 1.7e-16 60.5 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.27 GBG72923.1 - 0.0014 18.1 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG72923.1 - 0.019 14.8 0.0 0.059 13.2 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH PF17917.1 GBG72924.1 - 2.1e-16 60.1 0.7 4.1e-16 59.2 0.7 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72924.1 - 4.3e-10 39.5 0.0 8.3e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72926.1 - 3.1e-33 113.8 0.0 7e-33 112.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72926.1 - 4.2e-27 94.5 0.0 1.5e-26 92.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72926.1 - 1.8e-16 60.0 0.2 3.7e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG72926.1 - 9.5e-14 51.3 0.0 7.1e-06 25.8 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72926.1 - 5.1e-12 46.3 0.0 3.1e-05 24.5 0.0 3.2 3 0 0 3 3 3 2 Aspartyl protease rve PF00665.26 GBG72926.1 - 4e-11 43.2 0.0 9.7e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG72926.1 - 5e-09 36.6 0.0 0.001 19.6 0.0 3.0 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG72926.1 - 0.00037 20.3 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG72926.1 - 0.012 15.2 0.0 4.6 6.7 0.0 2.4 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG72927.1 - 1.4e-12 47.6 0.0 3.1e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 GBG72927.1 - 1.5e-06 27.9 5.2 1.6e-06 27.8 0.8 2.8 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region rve PF00665.26 GBG72927.1 - 3.9e-05 23.8 0.0 0.00018 21.6 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG72927.1 - 0.0045 17.2 0.1 0.038 14.3 0.1 2.7 1 0 0 1 1 1 1 Retrotransposon gag protein AT_hook PF02178.19 GBG72927.1 - 0.061 13.2 22.4 0.065 13.1 3.3 3.3 3 0 0 3 3 3 0 AT hook motif DUF2951 PF11166.8 GBG72927.1 - 1.7 8.9 5.4 1.7 8.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) Baculo_PEP_C PF04513.12 GBG72927.1 - 5.5 7.0 17.6 0.2 11.7 5.5 3.3 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus gag-asp_proteas PF13975.6 GBG72929.1 - 9.7e-08 32.5 0.1 2.9e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG72929.1 - 0.0001 22.9 0.1 0.00036 21.1 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG72929.1 - 0.0032 17.2 0.3 0.0078 16.0 0.3 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG72929.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG72929.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) COG2 PF06148.11 GBG72929.1 - 0.018 15.1 1.5 0.018 15.1 1.5 2.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 GBG72929.1 - 0.2 9.6 0.2 0.31 8.9 0.2 1.3 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 GBG72929.1 - 0.25 10.6 4.3 0.47 9.8 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FYVE PF01363.21 GBG72930.1 - 0.075 13.2 1.9 0.22 11.7 1.6 1.8 2 0 0 2 2 2 0 FYVE zinc finger HAUS-augmin3 PF14932.6 GBG72932.1 - 0.0096 15.5 9.5 0.0096 15.5 9.5 2.2 2 1 1 3 3 3 1 HAUS augmin-like complex subunit 3 COG2 PF06148.11 GBG72932.1 - 0.022 14.8 4.4 0.022 14.8 4.4 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.11 GBG72932.1 - 0.04 14.2 18.3 0.16 12.2 17.9 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Filament PF00038.21 GBG72932.1 - 0.29 10.7 24.8 1.6 8.2 21.9 2.6 1 1 0 1 1 1 0 Intermediate filament protein TFA2_Winged_2 PF18121.1 GBG72932.1 - 0.66 9.7 5.6 0.44 10.3 1.4 2.6 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Iron_permease PF04120.12 GBG72932.1 - 0.98 9.2 6.0 1.2 8.9 0.1 2.5 3 0 0 3 3 3 0 Low affinity iron permease Nup54 PF13874.6 GBG72932.1 - 1.4 9.0 11.2 16 5.6 3.5 3.2 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF812 PF05667.11 GBG72932.1 - 3.6 6.3 21.5 6.6 5.5 21.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) UPF0242 PF06785.11 GBG72932.1 - 5.1 7.1 19.5 19 5.3 19.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 GBG72932.1 - 7.8 6.5 29.4 2.4 8.2 9.5 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TFIIA PF03153.13 GBG72933.1 - 0.37 10.7 21.7 0.11 12.5 18.9 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.9 GBG72934.1 - 1.9 7.5 12.7 3.8 6.5 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RVT_1 PF00078.27 GBG72935.1 - 3.7e-27 95.3 0.0 8e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG72935.1 - 3e-10 40.3 0.1 6.6e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72935.1 - 3.9e-07 30.3 0.2 1.3e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG72935.1 - 0.021 14.8 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Phage_pRha PF09669.10 GBG72935.1 - 0.16 12.6 0.0 0.59 10.7 0.0 2.0 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) SlyX PF04102.12 GBG72936.1 - 0.044 14.4 1.1 0.044 14.4 1.1 2.8 2 1 1 3 3 3 0 SlyX SKI PF01202.22 GBG72936.1 - 0.099 12.8 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Shikimate kinase CLZ PF16526.5 GBG72936.1 - 2.4 8.6 5.7 3.4 8.1 0.3 3.2 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RT_RNaseH_2 PF17919.1 GBG72937.1 - 3.6e-30 103.9 0.0 6.9e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72937.1 - 6.2e-27 94.0 0.1 1.2e-26 93.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG72937.1 - 5.1e-18 64.9 0.1 1e-17 63.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG72937.1 - 5.1e-16 58.9 0.0 8.6e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG72937.1 - 0.062 13.6 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG72937.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DUF659 PF04937.15 GBG72938.1 - 1.3e-38 132.3 0.0 3e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG72939.1 - 1.3e-27 96.7 0.0 6.2e-27 94.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72939.1 - 6.2e-19 67.9 0.3 1.6e-18 66.6 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72939.1 - 6.4e-08 32.8 0.2 2.2e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG72939.1 - 2.5e-06 27.7 0.2 7.2e-06 26.2 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG72939.1 - 0.018 15.3 0.1 0.018 15.3 0.1 4.5 5 1 1 6 6 6 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG72939.1 - 0.073 13.3 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger V_ATPase_I PF01496.19 GBG72939.1 - 1.9 6.3 4.8 3.5 5.4 4.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ThiS PF02597.20 GBG72939.1 - 4.5 8.0 4.5 1.5 9.5 0.4 2.5 2 0 0 2 2 2 0 ThiS family Snapin_Pallidin PF14712.6 GBG72939.1 - 9 6.8 18.2 0.064 13.7 4.8 3.7 4 0 0 4 4 4 0 Snapin/Pallidin RT_RNaseH_2 PF17919.1 GBG72941.1 - 1.5e-26 92.4 0.0 5.1e-26 90.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72941.1 - 2.2e-24 85.8 0.0 6.3e-24 84.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72941.1 - 1.9e-20 73.3 0.0 3.8e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG72941.1 - 1.1e-07 32.0 0.0 3.6e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG72941.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease S4_2 PF13275.6 GBG72941.1 - 0.1 12.4 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 S4 domain RT_RNaseH_2 PF17919.1 GBG72942.1 - 9.9e-27 92.9 0.0 3.1e-26 91.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72942.1 - 1.3e-24 86.4 0.0 3.8e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72942.1 - 1.1e-20 74.1 0.0 2.3e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72942.1 - 0.00067 19.7 0.2 0.0017 18.4 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG72942.1 - 0.049 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG72943.1 - 1.5e-34 118.0 0.1 3.2e-34 117.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72943.1 - 2.1e-30 105.1 0.1 4.4e-30 104.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72943.1 - 5e-27 94.9 0.1 8.4e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72943.1 - 3.9e-18 65.3 0.2 1e-17 64.0 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG72943.1 - 0.0016 18.6 0.0 0.0075 16.5 0.0 2.2 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG72943.1 - 0.0048 17.1 0.0 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG72944.1 - 1.4e-17 64.0 0.6 1.1e-14 54.5 0.0 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG72944.1 - 1e-07 31.8 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG72944.1 - 3.9e-06 27.4 0.0 8.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG72944.1 - 0.0007 20.1 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG72944.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DHC_N1 PF08385.12 GBG72946.1 - 1.3e-06 27.3 0.0 2.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 SEN1_N PF12726.7 GBG72946.1 - 0.02 13.1 0.1 0.026 12.8 0.1 1.0 1 0 0 1 1 1 0 SEN1 N terminal DHC_N1 PF08385.12 GBG72947.1 - 0.0025 16.5 0.0 0.0037 16.0 0.0 1.2 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 RVT_1 PF00078.27 GBG72948.1 - 2.1e-27 96.1 0.1 2.8e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72949.1 - 3e-32 110.6 0.0 6.3e-32 109.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72949.1 - 1.3e-30 105.8 0.1 2.9e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72949.1 - 2.9e-23 82.5 0.1 5.4e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG72949.1 - 3.4e-17 62.3 0.1 7.2e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG72949.1 - 1.9e-16 60.3 0.0 5.7e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG72949.1 - 0.061 13.6 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG72950.1 - 4.4e-30 104.1 0.0 1.1e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72950.1 - 2.2e-21 75.8 0.0 1.1e-20 73.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase MREG PF15812.5 GBG72950.1 - 0.035 14.4 2.0 0.12 12.7 2.0 1.9 1 0 0 1 1 1 0 Melanoregulin Phage_GPO PF05929.11 GBG72950.1 - 0.21 11.2 0.0 0.21 11.2 0.0 3.0 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase P21-Arc PF04062.14 GBG72951.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 ARP2/3 complex ARPC3 (21 kDa) subunit Integrase_H2C2 PF17921.1 GBG72952.1 - 2.1e-34 117.4 1.1 2.4e-19 69.2 0.3 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG72952.1 - 2.7e-25 88.7 0.2 6.2e-25 87.5 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72952.1 - 4.7e-21 74.7 0.0 3.7e-18 65.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG72952.1 - 6.8e-13 48.9 0.0 1e-06 28.9 0.0 3.0 2 0 0 2 2 2 2 Integrase core domain DHC_N1 PF08385.12 GBG72952.1 - 9.1e-11 41.1 0.3 2.3e-10 39.8 0.2 1.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 RVT_1 PF00078.27 GBG72952.1 - 4.7e-07 29.6 0.0 9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG72952.1 - 5.9e-05 23.2 0.1 0.00055 20.1 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger APG17 PF04108.12 GBG72952.1 - 0.03 13.5 0.0 0.57 9.2 0.0 2.4 2 0 0 2 2 2 0 Autophagy protein Apg17 Mannitol_dh_C PF08125.13 GBG72952.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain AAA_6 PF12774.7 GBG72953.1 - 1.7e-126 421.7 0.0 7.1e-126 419.6 0.0 2.2 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 GBG72953.1 - 1.3e-101 340.6 0.0 5.2e-101 338.6 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 GBG72953.1 - 8.7e-66 221.2 4.7 1e-65 221.0 0.0 3.4 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 GBG72953.1 - 2.2e-56 191.1 0.0 5.2e-56 189.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 GBG72953.1 - 2e-42 144.7 0.0 8e-34 116.7 0.0 4.3 4 0 0 4 4 4 3 P-loop containing dynein motor region MT PF12777.7 GBG72953.1 - 2.2e-37 128.9 1.8 2.2e-37 128.9 1.8 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor RT_RNaseH_2 PF17919.1 GBG72953.1 - 4.8e-30 103.5 0.0 1.6e-29 101.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72953.1 - 5.2e-29 101.3 0.2 1.9e-28 99.5 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_5 PF07728.14 GBG72953.1 - 9.6e-29 100.1 0.0 1.2e-11 44.7 0.0 5.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) RT_RNaseH PF17917.1 GBG72953.1 - 5.4e-27 94.1 0.2 6.8e-26 90.6 0.0 2.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase AAA_lid_11 PF18198.1 GBG72953.1 - 9.2e-26 90.6 0.0 2.1e-16 60.1 0.0 2.7 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GBG72953.1 - 1.4e-20 73.6 0.0 1.3e-19 70.4 0.0 2.9 3 0 0 3 3 1 1 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 GBG72953.1 - 3.9e-20 72.6 0.0 1.4e-05 25.5 0.0 5.2 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) Dynein_C PF18199.1 GBG72953.1 - 1.5e-18 67.1 0.0 5.4e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain rve PF00665.26 GBG72953.1 - 1.8e-14 54.0 0.0 6.9e-14 52.1 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain AAA_22 PF13401.6 GBG72953.1 - 3.2e-13 50.1 6.5 0.017 15.4 0.1 6.9 7 1 0 7 7 5 3 AAA domain Dynein_AAA_lid PF17852.1 GBG72953.1 - 4.4e-12 46.2 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 GBG72953.1 - 6.8e-11 42.8 7.1 0.51 10.7 0.0 7.0 5 1 0 6 6 5 3 AAA ATPase domain AAA_33 PF13671.6 GBG72953.1 - 1e-07 32.2 0.1 1.3 9.2 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 GBG72953.1 - 1.8e-07 31.1 0.0 1.2 8.8 0.0 5.2 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 GBG72953.1 - 5.2e-07 29.0 0.0 0.051 12.6 0.0 3.7 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 GBG72953.1 - 3.6e-06 27.5 9.4 0.21 12.2 0.0 5.6 5 0 0 5 5 4 2 AAA domain Integrase_H2C2 PF17921.1 GBG72953.1 - 4.3e-06 26.7 0.5 2.5e-05 24.3 0.5 2.4 1 1 0 1 1 1 1 Integrase zinc binding domain Rad17 PF03215.15 GBG72953.1 - 7.7e-06 25.9 0.1 1.4 8.8 0.0 4.2 4 0 0 4 4 4 1 Rad17 P-loop domain gag-asp_proteas PF13975.6 GBG72953.1 - 1e-05 26.0 0.0 5.2e-05 23.7 0.0 2.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease IstB_IS21 PF01695.17 GBG72953.1 - 1.6e-05 24.7 0.1 1.8 8.2 0.0 4.5 4 0 0 4 4 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 GBG72953.1 - 1.8e-05 24.2 1.8 0.85 9.0 0.1 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 GBG72953.1 - 2.4e-05 24.5 0.0 0.00011 22.4 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA_24 PF13479.6 GBG72953.1 - 4.2e-05 23.4 0.2 8 6.1 0.0 4.6 4 0 0 4 4 4 0 AAA domain Asp_protease_2 PF13650.6 GBG72953.1 - 5.1e-05 23.8 0.0 0.00015 22.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RNA_helicase PF00910.22 GBG72953.1 - 0.00016 22.0 0.0 12 6.3 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_19 PF13245.6 GBG72953.1 - 0.00021 21.7 5.2 0.44 10.9 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 GBG72953.1 - 0.00035 20.2 0.5 1.5 8.3 0.0 4.6 4 0 0 4 4 4 1 AAA domain Retrotrans_gag PF03732.17 GBG72953.1 - 0.00037 20.7 9.9 1.5 9.2 0.0 6.8 7 0 0 7 7 6 1 Retrotransposon gag protein ABC_tran PF00005.27 GBG72953.1 - 0.00063 20.3 3.9 2 8.9 0.0 4.9 5 0 0 5 5 3 1 ABC transporter AAA_28 PF13521.6 GBG72953.1 - 0.00082 19.7 0.5 4.4 7.5 0.0 5.1 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 GBG72953.1 - 0.0013 18.4 0.2 4 7.3 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_14 PF13173.6 GBG72953.1 - 0.0038 17.3 0.0 0.25 11.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 GBG72953.1 - 0.014 15.2 0.0 0.014 15.2 0.0 6.9 9 0 0 9 9 7 0 AAA domain RuvB_N PF05496.12 GBG72953.1 - 0.024 14.4 0.1 0.71 9.6 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 GBG72953.1 - 0.029 14.1 0.0 5.7 6.6 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain zf-CCHC PF00098.23 GBG72953.1 - 0.04 14.0 2.2 0.095 12.8 2.2 1.7 1 0 0 1 1 1 0 Zinc knuckle AAA_23 PF13476.6 GBG72953.1 - 0.28 11.7 0.0 0.28 11.7 0.0 6.1 6 1 0 6 6 3 0 AAA domain NACHT PF05729.12 GBG72953.1 - 0.35 10.8 2.0 50 3.8 0.0 4.0 3 0 0 3 3 3 0 NACHT domain DUF4746 PF15928.5 GBG72953.1 - 2.1 7.7 9.2 5.9 6.2 9.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAA_6 PF12774.7 GBG72955.1 - 1.7e-126 421.7 0.0 7e-126 419.6 0.0 2.2 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 GBG72955.1 - 1.3e-101 340.6 0.0 5.2e-101 338.6 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 GBG72955.1 - 8.9e-66 221.2 4.8 1e-65 221.0 0.0 3.4 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 GBG72955.1 - 2.1e-56 191.1 0.0 5.2e-56 189.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 GBG72955.1 - 2e-42 144.8 0.0 7.9e-34 116.7 0.0 4.3 4 0 0 4 4 4 3 P-loop containing dynein motor region MT PF12777.7 GBG72955.1 - 2.2e-37 128.9 1.8 2.2e-37 128.9 1.8 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor RT_RNaseH_2 PF17919.1 GBG72955.1 - 4.8e-30 103.5 0.0 1.6e-29 101.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG72955.1 - 5.1e-29 101.4 0.2 1.9e-28 99.5 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_5 PF07728.14 GBG72955.1 - 9.2e-29 100.2 0.0 1.2e-11 44.8 0.0 5.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) RT_RNaseH PF17917.1 GBG72955.1 - 5.4e-27 94.1 0.2 6.8e-26 90.6 0.0 2.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase AAA_lid_11 PF18198.1 GBG72955.1 - 9e-26 90.6 0.0 2.1e-16 60.2 0.0 2.7 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GBG72955.1 - 1.3e-20 73.6 0.0 1.3e-19 70.4 0.0 2.9 3 0 0 3 3 1 1 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 GBG72955.1 - 3.7e-20 72.7 0.0 1.4e-05 25.5 0.0 5.2 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) Dynein_C PF18199.1 GBG72955.1 - 1.4e-18 67.1 0.0 5.4e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain rve PF00665.26 GBG72955.1 - 1.7e-14 54.0 0.0 6.9e-14 52.1 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain AAA_22 PF13401.6 GBG72955.1 - 2.8e-13 50.3 6.4 0.017 15.4 0.0 6.9 7 1 0 7 7 5 3 AAA domain Dynein_AAA_lid PF17852.1 GBG72955.1 - 4.4e-12 46.2 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 GBG72955.1 - 3.3e-09 37.3 12.7 0.51 10.7 0.0 7.0 6 1 0 7 7 5 3 AAA ATPase domain AAA_33 PF13671.6 GBG72955.1 - 9.8e-08 32.3 0.1 1.3 9.2 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 GBG72955.1 - 1.7e-07 31.1 0.0 1.2 8.9 0.0 5.2 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 GBG72955.1 - 5e-07 29.0 0.0 0.05 12.6 0.0 3.7 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 GBG72955.1 - 3.5e-06 27.6 9.4 0.2 12.2 0.0 5.6 5 0 0 5 5 4 2 AAA domain Integrase_H2C2 PF17921.1 GBG72955.1 - 4.3e-06 26.7 0.5 2.5e-05 24.3 0.5 2.4 1 1 0 1 1 1 1 Integrase zinc binding domain Rad17 PF03215.15 GBG72955.1 - 7.5e-06 26.0 0.1 1.4 8.8 0.0 4.2 4 0 0 4 4 4 1 Rad17 P-loop domain gag-asp_proteas PF13975.6 GBG72955.1 - 1e-05 26.0 0.0 5.2e-05 23.7 0.0 2.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease IstB_IS21 PF01695.17 GBG72955.1 - 1.6e-05 24.7 0.1 1.8 8.3 0.0 4.5 4 0 0 4 4 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 GBG72955.1 - 1.7e-05 24.3 1.8 0.85 9.0 0.1 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 GBG72955.1 - 2.4e-05 24.5 0.0 0.00011 22.4 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA_24 PF13479.6 GBG72955.1 - 4e-05 23.4 0.2 8 6.1 0.0 4.6 4 0 0 4 4 4 0 AAA domain Asp_protease_2 PF13650.6 GBG72955.1 - 5e-05 23.9 0.0 0.00015 22.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RNA_helicase PF00910.22 GBG72955.1 - 0.00016 22.0 0.0 12 6.3 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_19 PF13245.6 GBG72955.1 - 0.0002 21.7 5.2 0.43 10.9 0.0 5.0 4 0 0 4 4 4 1 AAA domain Retrotrans_gag PF03732.17 GBG72955.1 - 0.00035 20.8 9.9 1.4 9.2 0.0 6.8 7 0 0 7 7 6 1 Retrotransposon gag protein AAA_25 PF13481.6 GBG72955.1 - 0.00036 20.2 0.6 1.5 8.3 0.0 4.6 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 GBG72955.1 - 0.00061 20.3 3.9 2 9.0 0.0 4.9 5 0 0 5 5 3 1 ABC transporter AAA_28 PF13521.6 GBG72955.1 - 0.00078 19.7 0.5 4.4 7.5 0.0 5.1 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 GBG72955.1 - 0.0013 18.5 0.2 4 7.3 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_14 PF13173.6 GBG72955.1 - 0.0037 17.3 0.0 0.25 11.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 GBG72955.1 - 0.014 15.2 0.0 0.014 15.2 0.0 7.0 9 0 0 9 9 7 0 AAA domain RuvB_N PF05496.12 GBG72955.1 - 0.023 14.4 0.1 0.7 9.6 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 GBG72955.1 - 0.028 14.1 0.0 5.7 6.6 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain zf-CCHC PF00098.23 GBG72955.1 - 0.04 14.0 2.2 0.094 12.8 2.2 1.7 1 0 0 1 1 1 0 Zinc knuckle AAA_23 PF13476.6 GBG72955.1 - 0.27 11.7 0.0 0.27 11.7 0.0 6.1 6 1 0 6 6 3 0 AAA domain DUF4746 PF15928.5 GBG72955.1 - 2.1 7.7 9.2 5.8 6.2 9.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RT_RNaseH PF17917.1 GBG72956.1 - 3.2e-30 104.5 0.0 4.6e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG72956.1 - 4.5e-24 84.4 0.0 6e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG72956.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Methyltransf_23 PF13489.6 GBG72956.1 - 0.91 9.3 4.9 3.5 7.4 0.1 2.8 2 1 1 3 3 3 0 Methyltransferase domain RT_RNaseH_2 PF17919.1 GBG72957.1 - 0.0052 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72957.1 - 0.042 14.1 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Glyco_tran_WbsX PF14307.6 GBG72958.1 - 0.098 12.1 5.7 1.1 8.6 0.2 2.6 2 1 0 2 2 2 0 Glycosyltransferase WbsX Protocadherin PF08374.11 GBG72958.1 - 0.45 10.5 3.0 0.97 9.4 3.0 1.5 1 0 0 1 1 1 0 Protocadherin Atg14 PF10186.9 GBG72958.1 - 3.5 6.6 25.2 1.5 7.9 6.8 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DNA_pack_N PF02500.15 GBG72958.1 - 8.1 6.2 12.6 0.44 10.3 2.0 2.3 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Integrase_H2C2 PF17921.1 GBG72959.1 - 8.3e-18 64.2 2.3 3.1e-17 62.4 1.6 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG72959.1 - 2.1e-09 37.6 0.0 7.6e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG72959.1 - 0.0014 18.5 0.1 0.0039 17.1 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG72959.1 - 0.014 15.6 1.2 0.032 14.4 1.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG72960.1 - 0.014 15.7 0.1 0.5 10.7 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein Baculo_PEP_C PF04513.12 GBG72960.1 - 0.044 13.8 2.1 0.073 13.1 2.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 GBG72960.1 - 0.099 12.7 0.3 0.4 10.8 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) HIP1_clath_bdg PF16515.5 GBG72960.1 - 1.6 9.4 9.9 5.7 7.6 0.3 2.7 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 GBG72960.1 - 2.5 7.4 12.5 3.5 6.9 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 GBG72960.1 - 5.9 7.6 12.7 0.21 12.2 2.4 3.0 2 1 1 3 3 3 0 SlyX TadF PF16964.5 GBG72961.1 - 0.38 10.5 4.9 0.53 10.0 4.9 1.3 1 0 0 1 1 1 0 Putative tight adherence pilin protein F NosD PF05048.13 GBG72962.1 - 1.8e-05 24.1 16.8 0.0024 17.2 5.5 2.5 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 GBG72962.1 - 2.8 7.2 7.8 0.39 10.0 0.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1565) ALG11_N PF15924.5 GBG72963.1 - 3e-84 282.3 0.0 4.1e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 GBG72963.1 - 1.9e-24 86.1 0.0 6.3e-24 84.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG72963.1 - 6.5e-13 49.3 0.1 1.4e-10 41.7 0.1 2.7 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG72963.1 - 3.7e-05 24.0 0.0 0.00015 22.1 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG72963.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DUF3328 PF11807.8 GBG72963.1 - 0.13 12.0 0.1 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) SR-25 PF10500.9 GBG72963.1 - 1.2 8.7 16.7 2.5 7.6 16.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HemY_N PF07219.13 GBG72963.1 - 3.6 7.8 6.8 0.43 10.8 1.6 2.1 2 0 0 2 2 2 0 HemY protein N-terminus zf-CCHC_6 PF15288.6 GBG72964.1 - 0.00027 20.7 2.8 0.00027 20.7 2.8 2.0 2 0 0 2 2 2 1 Zinc knuckle Aldedh PF00171.22 GBG72965.1 - 2.6e-161 537.3 0.5 1.4e-110 370.0 0.0 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family AT_hook PF02178.19 GBG72965.1 - 0.13 12.2 3.7 0.31 11.0 3.7 1.7 1 0 0 1 1 1 0 AT hook motif RVT_1 PF00078.27 GBG72966.1 - 2.6e-26 92.5 0.3 5.9e-26 91.4 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG72966.1 - 4.6e-24 84.3 0.0 2.3e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG72966.1 - 2.7e-23 82.3 0.0 5.6e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG72966.1 - 5.3e-09 36.6 0.0 1.2e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG72966.1 - 1.1e-07 31.7 0.0 2.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG72966.1 - 1.4e-06 28.8 0.0 3.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG72966.1 - 1.6e-06 28.3 0.0 5.6e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG72966.1 - 0.0016 18.6 0.1 0.0088 16.3 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG72966.1 - 0.0021 17.8 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease GLTT PF01744.20 GBG72967.1 - 0.0013 18.5 0.1 0.012 15.3 0.1 2.4 2 0 0 2 2 2 1 GLTT repeat (6 copies) Stig1 PF04885.13 GBG72968.1 - 3.1e-18 66.6 29.7 7.2e-18 65.4 30.1 1.3 1 1 0 1 1 1 1 Stigma-specific protein, Stig1 UPF0016 PF01169.19 GBG72969.1 - 7e-40 135.2 30.6 7.1e-21 74.3 7.2 3.2 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 PetL PF05115.14 GBG72969.1 - 0.061 13.3 0.2 0.061 13.3 0.2 3.5 4 0 0 4 4 4 0 Cytochrome B6-F complex subunit VI (PetL) Fasciclin PF02469.22 GBG72970.1 - 3.2e-18 66.2 0.0 4.1e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Phytochelatin_C PF09328.10 GBG72970.1 - 0.18 11.1 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) zf-CCHC PF00098.23 GBG72971.1 - 0.36 11.0 1.9 0.65 10.2 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Prenyltrans PF00432.21 GBG72972.1 - 2.6e-45 151.8 7.4 1e-10 41.2 0.4 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 GBG72972.1 - 0.0012 18.0 0.0 0.84 8.7 0.0 2.9 1 1 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 GBG72972.1 - 0.049 12.7 0.0 0.28 10.2 0.0 1.9 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain DUF659 PF04937.15 GBG72973.1 - 5.3e-10 39.3 0.0 1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DDE_Tnp_4 PF13359.6 GBG72974.1 - 7.9e-19 67.9 0.0 1.5e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG72974.1 - 8.3e-09 35.3 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG72974.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG72975.1 - 1.6e-09 38.0 2.7 1.9e-09 37.8 0.6 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG72975.1 - 0.0071 16.6 0.7 0.02 15.2 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like LST1 PF05083.13 GBG72975.1 - 1 9.7 6.3 14 6.0 0.2 3.4 3 0 0 3 3 3 0 LST-1 protein Pox_F11 PF04943.12 GBG72976.1 - 0.077 12.1 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein DUF1989 PF09347.10 GBG72976.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) DUF287 PF03384.14 GBG72976.1 - 0.45 10.9 4.5 0.31 11.5 0.8 2.4 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 Pkinase_Tyr PF07714.17 GBG72977.1 - 2.9e-36 125.1 0.0 1.2e-35 123.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG72977.1 - 1.4e-35 122.9 0.0 2.2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG72977.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GBG72978.1 - 1.7e-36 125.9 0.0 5.2e-36 124.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG72978.1 - 4.6e-35 121.3 0.0 6.9e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain NAD_kinase PF01513.21 GBG72979.1 - 3e-12 46.3 0.0 3.3e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GBG72979.1 - 0.016 14.8 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 GBG72980.1 - 1.6e-12 47.2 0.0 1.7e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GBG72980.1 - 0.015 14.9 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF760 PF05542.11 GBG72981.1 - 5e-43 145.4 2.2 2.8e-22 78.9 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF760) DUF4201 PF13870.6 GBG72983.1 - 4.3e-34 117.8 30.4 4.3e-34 117.8 30.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) TetR_C_19 PF17924.1 GBG72983.1 - 0.14 12.8 9.7 0.16 12.5 2.2 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MCM PF00493.23 GBG72984.1 - 5.6e-102 339.6 0.0 8.8e-102 338.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GBG72984.1 - 1.2e-39 135.0 0.3 2.8e-39 133.8 0.3 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GBG72984.1 - 9.5e-27 93.3 1.4 2.1e-26 92.2 1.4 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 GBG72984.1 - 6.5e-21 74.6 0.0 1.6e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 GBG72984.1 - 1.7e-19 70.4 1.2 4.8e-19 68.9 1.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GBG72984.1 - 1.8e-08 34.0 0.0 5.1e-07 29.3 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GBG72984.1 - 0.0002 21.4 0.0 0.00046 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GBG72984.1 - 0.0012 18.7 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GBG72984.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Churchill PF06573.11 GBG72984.1 - 0.13 12.6 0.2 1.7 9.0 0.1 2.6 2 0 0 2 2 2 0 Churchill protein GIDA_assoc PF13932.6 GBG72984.1 - 0.14 12.3 2.0 0.16 12.1 0.6 1.8 2 0 0 2 2 2 0 GidA associated domain DUF1754 PF08555.10 GBG72985.1 - 0.31 11.9 18.1 0.76 10.6 18.1 1.8 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) BING4CT PF08149.11 GBG72986.1 - 1.5e-35 120.9 0.0 2.9e-34 116.7 0.0 2.8 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 GBG72986.1 - 1.2e-07 32.3 1.3 0.00011 22.9 0.1 4.9 5 1 1 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG72986.1 - 6.7e-06 26.3 0.0 0.9 9.9 0.0 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IHABP4_N PF16174.5 GBG72986.1 - 0.0027 18.4 3.2 0.0027 18.4 3.2 3.0 3 0 0 3 3 3 1 Intracellular hyaluronan-binding protein 4 N-terminal WD40_like PF17005.5 GBG72986.1 - 0.081 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Kinesin PF00225.23 GBG72987.1 - 1.6e-57 195.0 0.0 2.7e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG72987.1 - 0.00069 19.6 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Replicase PF03090.17 GBG72987.1 - 0.048 13.5 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Replicase family p450 PF00067.22 GBG72988.1 - 1.4e-66 225.2 0.0 1.7e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2336 PF10098.9 GBG72988.1 - 0.031 13.8 0.3 0.054 13.0 0.1 1.4 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) Voltage_CLC PF00654.20 GBG72989.1 - 1.2e-13 51.1 5.0 2.5e-13 50.0 2.0 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 GBG72990.1 - 9.3e-13 48.4 0.0 5.7e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain Voltage_CLC PF00654.20 GBG72990.1 - 2.6e-10 40.1 0.9 4e-10 39.5 0.9 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel ANF_receptor PF01094.28 GBG72990.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Sec23_trunk PF04811.15 GBG72991.1 - 5.5e-67 225.9 0.0 7.6e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GBG72991.1 - 2.3e-25 89.2 0.0 4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 GBG72991.1 - 3.1e-22 78.3 0.1 5.7e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GBG72991.1 - 1.8e-18 66.3 4.4 3.3e-18 65.4 4.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GBG72991.1 - 1.4e-10 40.9 0.0 2.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 GBG72991.1 - 0.1 12.0 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zinc_ribbon_10 PF10058.9 GBG72991.1 - 0.25 11.1 0.4 0.47 10.2 0.4 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Calreticulin PF00262.18 GBG72992.1 - 2.4e-80 270.1 10.9 5.7e-60 203.1 2.1 3.0 2 1 1 3 3 3 2 Calreticulin family AP3D1 PF06375.11 GBG72992.1 - 0.0096 16.2 10.2 0.018 15.3 10.2 1.4 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 CDC45 PF02724.14 GBG72992.1 - 1.3 7.2 13.5 2.3 6.4 13.5 1.3 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.16 GBG72992.1 - 5.9 6.2 10.6 10 5.4 10.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TUTF7_u4 PF16631.5 GBG72993.1 - 0.05 14.2 0.0 14 6.4 0.0 3.1 2 0 0 2 2 2 0 Unstructured region 4 on terminal uridylyltransferase 7 Anillin_N PF16018.5 GBG72993.1 - 0.074 13.7 6.0 3.6 8.3 0.9 3.1 2 0 0 2 2 2 0 Anillin N-terminus Med3 PF11593.8 GBG72993.1 - 7.6 5.6 14.2 16 4.6 14.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NAD_binding_1 PF00175.21 GBG72995.1 - 6.1e-29 100.9 0.0 9.6e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GBG72995.1 - 0.0031 17.8 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Nebulin PF00880.18 GBG72995.1 - 0.08 12.9 0.3 0.08 12.9 0.3 2.4 2 0 0 2 2 2 0 Nebulin repeat Rhodanese PF00581.20 GBG72996.1 - 7.1e-10 39.4 0.0 2.9e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain BUD22 PF09073.10 GBG72998.1 - 0.02 14.2 7.7 0.024 14.0 7.7 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG72998.1 - 0.19 10.5 2.9 0.26 10.0 2.9 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GBG72998.1 - 0.67 9.7 7.0 0.94 9.2 7.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GBG72998.1 - 2 6.6 11.9 2.4 6.3 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG72998.1 - 4.2 5.5 17.3 5.2 5.2 17.3 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG72998.1 - 8.2 5.7 16.4 11 5.4 16.4 1.1 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 GBG72998.1 - 9.6 5.3 9.8 14 4.8 9.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit N6_N4_Mtase PF01555.18 GBG72999.1 - 1.6e-06 28.0 0.0 2.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 DNA methylase Cons_hypoth95 PF03602.15 GBG72999.1 - 0.021 14.5 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 FA_hydroxylase PF04116.13 GBG73000.1 - 2.6e-29 102.2 17.9 3.1e-29 102.0 17.9 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily rve PF00665.26 GBG73001.1 - 2e-07 31.2 0.1 6e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain TPR_7 PF13176.6 GBG73001.1 - 0.016 15.2 2.0 41 4.5 0.0 4.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG73001.1 - 0.084 13.0 3.5 12 6.3 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PUF PF00806.19 GBG73001.1 - 0.14 11.9 0.0 6.2 6.7 0.0 2.7 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Fe-ADH PF00465.19 GBG73001.1 - 1.3 7.8 6.9 0.62 8.8 0.1 2.6 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase Rrn6 PF10214.9 GBG73001.1 - 3.4 6.0 12.6 0.75 8.2 9.1 1.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor SNAP PF14938.6 GBG73001.1 - 4.7 6.5 18.2 0.025 14.0 4.8 2.9 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP RVT_1 PF00078.27 GBG73002.1 - 1.2e-36 126.3 0.0 2.2e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73002.1 - 2.6e-30 104.4 0.1 1e-29 102.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73002.1 - 7.6e-29 100.1 0.1 2.2e-28 98.6 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73002.1 - 3.8e-16 58.9 0.3 8.8e-16 57.8 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73002.1 - 0.0054 16.9 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG73003.1 - 3.3e-30 105.3 0.0 5.5e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG73003.1 - 1.4e-06 28.8 0.0 4e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73003.1 - 1.9e-05 25.1 0.0 6.6e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG73003.1 - 0.0002 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Coatomer_WDAD PF04053.14 GBG73003.1 - 0.001 18.2 0.7 0.14 11.2 0.0 2.4 1 1 1 2 2 2 2 Coatomer WD associated region Clathrin PF00637.20 GBG73003.1 - 0.0012 18.7 0.8 0.32 10.8 0.3 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Asp_protease PF09668.10 GBG73003.1 - 0.0022 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease TPR_2 PF07719.17 GBG73003.1 - 0.0032 17.5 3.8 14 6.0 0.2 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 GBG73003.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein TPR_7 PF13176.6 GBG73003.1 - 0.089 12.9 2.7 3.2 8.0 0.1 3.8 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 GBG73003.1 - 0.093 12.7 0.9 19 5.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG73003.1 - 0.27 11.1 3.0 9 6.3 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 GBG73003.1 - 0.38 11.7 3.5 5.5 8.0 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat NOA36 PF06524.12 GBG73003.1 - 2.9 7.1 7.5 5.6 6.2 7.5 1.4 1 0 0 1 1 1 0 NOA36 protein RT_RNaseH_2 PF17919.1 GBG73004.1 - 6.3e-32 109.6 0.0 1.8e-31 108.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73004.1 - 5.2e-29 100.6 0.1 1.7e-28 98.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG73004.1 - 1.8e-07 31.0 0.0 4.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73004.1 - 4.1e-05 24.1 0.0 0.0001 22.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG73004.1 - 0.00036 20.8 0.0 0.0022 18.2 0.0 2.5 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG73004.1 - 0.00077 20.0 0.3 0.0032 18.0 0.0 2.2 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73004.1 - 0.016 15.0 0.0 0.31 10.8 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease DUF1758 PF05585.12 GBG73004.1 - 0.026 14.3 0.0 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG73004.1 - 0.53 9.9 0.0 0.53 9.9 0.0 2.9 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG73005.1 - 8.2e-35 120.3 0.0 1.4e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG73005.1 - 3.9e-07 30.7 6.2 1.3e-06 29.0 6.2 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase CCDC85 PF10226.9 GBG73006.1 - 0.046 13.4 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 CCDC85 family HALZ PF02183.18 GBG73006.1 - 0.27 11.5 2.9 0.33 11.2 0.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2385 PF09539.10 GBG73006.1 - 1.3 9.6 4.3 6.1 7.4 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2385) DUF3416 PF11896.8 GBG73006.1 - 1.5 9.1 5.2 2 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) HEAT PF02985.22 GBG73008.1 - 2.5e-06 27.2 0.8 0.033 14.4 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 GBG73008.1 - 0.00014 22.2 0.1 2.4 8.6 0.0 3.4 2 1 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.6 GBG73008.1 - 0.00053 20.4 1.4 0.34 11.4 0.0 4.2 3 2 2 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 GBG73008.1 - 0.0062 16.6 0.0 0.93 9.5 0.0 2.3 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GBG73008.1 - 0.079 13.6 0.0 0.61 10.7 0.0 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HIP1_clath_bdg PF16515.5 GBG73011.1 - 0.023 15.3 5.9 0.023 15.3 5.9 3.6 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BLOC1_2 PF10046.9 GBG73011.1 - 0.027 14.8 2.1 0.027 14.8 2.1 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 GBG73011.1 - 0.097 12.7 5.4 1.2 9.1 0.2 2.8 3 0 0 3 3 3 0 Laminin Domain II FliD_N PF02465.18 GBG73011.1 - 0.22 12.3 4.9 0.5 11.1 0.1 3.2 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus FUSC PF04632.12 GBG73011.1 - 0.29 9.6 11.4 0.42 9.1 11.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 GBG73011.1 - 0.7 9.9 3.6 4.4 7.4 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 GBG73011.1 - 1.2 8.4 12.7 3.3 7.0 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 GBG73011.1 - 3.3 8.2 21.5 0.81 10.2 2.3 4.1 4 1 0 4 4 4 0 Cell division protein ZapB Swi5 PF07061.11 GBG73011.1 - 5 7.3 11.9 4.7 7.4 0.7 3.6 3 0 0 3 3 3 0 Swi5 NPV_P10 PF05531.12 GBG73011.1 - 5.3 7.6 9.2 6.3 7.3 0.4 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 GBG73011.1 - 6 7.6 17.9 0.079 13.6 2.5 3.8 3 1 0 3 3 3 0 SlyX Spc24 PF08286.11 GBG73011.1 - 7.8 6.8 12.9 1.2 9.4 1.7 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 SET PF00856.28 GBG73012.1 - 2.2e-22 80.2 0.0 2.2e-22 80.2 0.0 4.0 4 1 0 4 4 4 1 SET domain AWS PF17907.1 GBG73012.1 - 1.8e-12 47.1 13.3 4.1e-12 45.9 13.3 1.7 1 0 0 1 1 1 1 AWS domain Calpain_inhib PF00748.19 GBG73013.1 - 1.1 9.7 5.9 0.71 10.4 0.4 2.8 2 0 0 2 2 2 0 Calpain inhibitor HA2 PF04408.23 GBG73014.1 - 1.5e-17 63.8 0.0 1.5e-17 63.8 0.0 2.6 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GBG73014.1 - 2e-14 53.7 0.0 4.7e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GBG73014.1 - 2.6e-12 47.0 0.0 6.1e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.14 GBG73014.1 - 1.1e-11 44.7 0.0 2e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 Dicer dimerisation domain dsrm PF00035.26 GBG73014.1 - 6.2e-11 42.8 0.0 0.00026 21.6 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 GBG73014.1 - 7e-09 35.7 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 GBG73014.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 GBG73014.1 - 0.023 14.7 0.0 0.15 12.0 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 GBG73014.1 - 0.028 13.9 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 GBG73014.1 - 0.054 13.8 0.1 0.14 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GBG73014.1 - 0.069 13.4 0.6 0.42 10.9 0.6 2.3 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 GBG73014.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1989 PF09347.10 GBG73015.1 - 0.08 12.6 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) DUF287 PF03384.14 GBG73015.1 - 0.2 12.1 1.1 0.45 11.0 1.1 1.6 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 Mito_carr PF00153.27 GBG73016.1 - 3.1e-38 129.6 1.7 1.9e-18 66.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Phos_pyr_kin PF08543.12 GBG73017.1 - 1.8e-07 30.8 0.0 3.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Abhydrolase_1 PF00561.20 GBG73019.1 - 7.9e-10 38.8 0.1 4.8e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG73019.1 - 3.5e-08 34.3 2.1 3.5e-08 34.3 2.1 2.9 2 1 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG73019.1 - 7.8e-08 31.9 0.0 1.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 RVT_1 PF00078.27 GBG73021.1 - 1.6e-40 139.0 0.0 3.9e-40 137.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG73022.1 - 6.8e-06 26.4 3.2 1.3e-05 25.4 3.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG73022.1 - 0.21 11.8 4.7 0.76 10.0 4.7 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Psb28 PF03912.14 GBG73023.1 - 3e-42 143.2 0.1 4e-42 142.8 0.1 1.2 1 0 0 1 1 1 1 Psb28 protein SR-25 PF10500.9 GBG73023.1 - 0.76 9.3 5.1 1.2 8.6 5.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.7 GBG73025.1 - 0.13 12.8 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RT_RNaseH_2 PF17919.1 GBG73026.1 - 2.4e-34 117.3 0.0 5.4e-34 116.2 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73026.1 - 6.4e-22 77.8 0.0 1.3e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73026.1 - 2.5e-09 37.4 0.1 1.8e-08 34.6 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG73026.1 - 0.00015 21.8 0.2 0.00049 20.1 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Tubulin PF00091.25 GBG73027.1 - 5.9e-66 222.4 0.0 8.2e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG73027.1 - 2.7e-51 173.0 0.1 4.2e-51 172.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GBG73027.1 - 0.0081 15.9 0.0 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain MMACHC PF16690.5 GBG73028.1 - 1.8e-06 27.8 0.6 0.00013 21.7 0.0 3.0 3 1 0 3 3 3 2 Methylmalonic aciduria and homocystinuria type C family Retrotrans_gag PF03732.17 GBG73029.1 - 0.0016 18.6 6.6 0.032 14.5 0.1 4.3 4 0 0 4 4 4 1 Retrotransposon gag protein DUF2408 PF10303.9 GBG73029.1 - 0.0073 16.9 7.8 0.036 14.6 7.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) AIP3 PF03915.13 GBG73029.1 - 0.017 14.2 5.0 0.03 13.4 5.0 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Ribosomal_60s PF00428.19 GBG73029.1 - 0.36 11.4 3.8 4.2 8.0 3.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein FUSC PF04632.12 GBG73029.1 - 1.8 7.0 16.2 0.028 13.0 3.7 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family TMPIT PF07851.13 GBG73029.1 - 5 6.3 7.1 0.33 10.1 1.0 2.0 2 0 0 2 2 2 0 TMPIT-like protein G0-G1_switch_2 PF15103.6 GBG73029.1 - 8.6 6.9 6.5 8.3 6.9 0.6 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 Spike_torovirin PF17072.5 GBG73030.1 - 0.17 9.0 1.3 0.23 8.5 1.3 1.1 1 0 0 1 1 1 0 Torovirinae spike glycoprotein Sorting_nexin PF03700.13 GBG73031.1 - 0.053 14.1 5.4 0.08 13.5 5.4 1.2 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain CCDC84 PF14968.6 GBG73032.1 - 9.6e-37 127.4 39.6 1.8e-17 64.0 13.2 5.1 3 2 2 5 5 5 4 Coiled coil protein 84 PCI PF01399.27 GBG73033.1 - 2.4e-13 50.5 0.1 1.2e-12 48.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain DUF410 PF04190.13 GBG73033.1 - 0.0033 17.3 2.3 0.0074 16.1 1.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF410) RVT_1 PF00078.27 GBG73035.1 - 2e-30 106.0 0.0 3.4e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73035.1 - 2.3e-22 78.9 0.0 6.6e-22 77.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73035.1 - 2.2e-21 76.1 0.0 4.5e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Methyltr_RsmB-F PF01189.17 GBG73035.1 - 1.7e-16 60.5 0.3 7.6e-07 29.0 0.0 3.5 3 0 0 3 3 3 3 16S rRNA methyltransferase RsmB/F RVP_2 PF08284.11 GBG73035.1 - 5.8e-11 42.3 0.0 1.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73035.1 - 7.1e-08 33.0 0.0 1.9e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73035.1 - 1.4e-05 25.6 0.0 4.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73035.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease TolA_bind_tri PF16331.5 GBG73035.1 - 0.017 15.2 3.9 0.049 13.7 3.9 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation Helicase_C PF00271.31 GBG73038.1 - 2.1e-18 66.7 0.0 1.5e-15 57.5 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 GBG73038.1 - 7.1e-18 65.0 0.0 1.6e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 GBG73038.1 - 4.8e-12 46.4 4.9 1.6e-11 44.7 4.9 2.0 1 0 0 1 1 1 1 RecQ zinc-binding Dimer_Tnp_hAT PF05699.14 GBG73039.1 - 3.8e-10 39.4 4.0 2.5e-09 36.8 3.3 2.5 2 1 0 2 2 2 1 hAT family C-terminal dimerisation region RSB_motif PF16294.5 GBG73040.1 - 1.3e-13 51.1 0.6 1.3e-13 51.1 0.6 14.8 4 1 3 7 7 7 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 GBG73040.1 - 1.2e-10 40.9 1.0 1.2e-10 40.9 1.0 2.5 3 0 0 3 3 3 1 SAP domain HeH PF12949.7 GBG73040.1 - 0.021 14.6 0.3 0.037 13.7 0.3 1.4 1 0 0 1 1 1 0 HeH/LEM domain RRM_1 PF00076.22 GBG73040.1 - 0.033 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 GBG73041.1 - 2.2e-44 151.8 0.0 2.7e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG73041.1 - 1.2e-41 142.7 0.0 1.4e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 GBG73041.1 - 0.22 11.7 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 ABC1 family AalphaY_MDB PF04611.12 GBG73042.1 - 0.15 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region TPT PF03151.16 GBG73044.1 - 2.3e-21 76.4 20.1 2.9e-21 76.1 20.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG73044.1 - 0.001 19.3 11.1 0.001 19.3 11.1 3.1 2 2 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 GBG73044.1 - 0.0025 17.1 24.4 0.0035 16.6 24.4 1.2 1 0 0 1 1 1 1 UAA transporter family MtN3_slv PF03083.16 GBG73044.1 - 0.026 14.5 2.7 0.11 12.6 2.7 2.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange TMEM234 PF10639.9 GBG73044.1 - 3.2 7.8 9.6 3.3 7.8 0.6 2.9 3 0 0 3 3 3 0 Putative transmembrane family 234 WLM PF08325.10 GBG73045.1 - 4.8e-52 176.8 0.5 1.1e-51 175.7 0.0 1.8 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.18 GBG73045.1 - 3.4e-10 39.1 11.4 1.8e-06 27.1 0.9 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 GBG73045.1 - 0.079 13.0 1.5 0.085 12.9 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 DZR PF12773.7 GBG73045.1 - 0.19 11.8 7.1 0.4 10.7 7.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 GBG73045.1 - 0.26 11.4 1.3 5.3 7.2 0.1 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-CW PF07496.15 GBG73045.1 - 1.2 9.2 7.9 0.32 11.1 1.9 2.9 2 1 1 3 3 3 0 CW-type Zinc Finger Vps36-NZF-N PF16988.5 GBG73045.1 - 2.3 7.7 10.2 15 5.1 0.7 3.1 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MBR1 PF17058.5 GBG73046.1 - 7.1 6.9 16.8 26 5.0 12.5 2.1 2 0 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 YIF1 PF03878.15 GBG73047.1 - 1.1e-65 221.5 0.4 1.4e-65 221.2 0.4 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 GBG73047.1 - 0.0042 16.8 13.8 0.0042 16.8 13.8 1.6 1 1 1 2 2 2 2 Yip1 domain OrfB_Zn_ribbon PF07282.11 GBG73048.1 - 0.077 12.9 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Gar1 PF04410.14 GBG73049.1 - 5.5e-36 123.7 0.0 5.5e-36 123.7 0.0 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Dimer_Tnp_hAT PF05699.14 GBG73050.1 - 2.2e-06 27.3 0.0 4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RRM_1 PF00076.22 GBG73051.1 - 6.8e-31 105.9 0.0 8.3e-18 64.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG73051.1 - 0.00036 20.3 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 GBG73051.1 - 0.00096 19.2 0.0 0.0071 16.4 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 GBG73051.1 - 0.087 12.9 0.0 0.72 9.9 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif RRM_1 PF00076.22 GBG73052.1 - 5.7e-31 106.2 0.0 7.5e-18 64.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG73052.1 - 0.00033 20.5 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 GBG73052.1 - 0.00082 19.4 0.0 0.0065 16.6 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 GBG73052.1 - 0.074 13.1 0.0 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Katanin_con80 PF13925.6 GBG73053.1 - 5.9e-46 156.4 0.0 6.8e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 con80 domain of Katanin SAP PF02037.27 GBG73056.1 - 4.8e-13 48.5 0.2 1.5e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 SAP domain eIF3_subunit PF08597.10 GBG73056.1 - 0.15 12.0 14.0 0.24 11.3 14.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SpoIIP PF07454.11 GBG73056.1 - 2.6 7.4 7.8 4.1 6.8 7.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 GBG73056.1 - 3.5 6.3 13.7 0.08 11.7 6.5 1.7 2 0 0 2 2 2 0 Presenilin Pox_MCEL PF03291.16 GBG73057.1 - 1.3e-87 294.0 0.0 1.7e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 GBG73057.1 - 4.2e-12 46.6 0.0 1.2e-11 45.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG73057.1 - 2.7e-09 37.6 0.0 5.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG73057.1 - 6.7e-07 30.0 0.0 2.2e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG73057.1 - 4.8e-06 26.4 0.1 2.8e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG73057.1 - 5.1e-06 26.4 0.0 8.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GBG73057.1 - 0.00061 19.1 0.1 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family NodS PF05401.11 GBG73057.1 - 0.016 14.9 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 GBG73057.1 - 0.023 14.0 0.0 0.081 12.2 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family REV PF00424.18 GBG73058.1 - 0.58 10.2 4.4 1.2 9.2 0.5 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) TssO PF17561.2 GBG73058.1 - 1.5 8.9 6.1 3.1 7.9 6.1 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF3138 PF11336.8 GBG73058.1 - 2.4 6.7 4.3 1.3 7.6 2.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) ANAPC4_WD40 PF12894.7 GBG73059.1 - 0.15 12.4 0.0 0.57 10.5 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-bind_4 PF13837.6 GBG73060.1 - 1e-11 45.0 4.4 1.7e-11 44.3 4.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG73060.1 - 0.018 15.2 1.4 0.029 14.5 1.4 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG73060.1 - 0.12 12.5 1.1 0.21 11.7 1.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain PAS_3 PF08447.12 GBG73060.1 - 0.27 11.6 3.3 16 5.9 0.2 2.7 1 1 2 3 3 3 0 PAS fold Katanin_con80 PF13925.6 GBG73061.1 - 4.8e-34 117.7 0.2 7.3e-34 117.1 0.2 1.2 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 GBG73061.1 - 3.8e-11 43.3 0.1 1.4e-06 28.9 0.0 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG73061.1 - 0.0096 16.2 0.0 0.53 10.6 0.0 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.14 GBG73061.1 - 0.15 10.3 2.4 0.21 9.8 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 GBG73061.1 - 1.5 7.8 6.5 2.9 6.8 6.5 1.4 1 0 0 1 1 1 0 Paf1 RBR PF17208.3 GBG73061.1 - 5.2 7.8 7.1 0.51 11.1 2.2 1.8 2 0 0 2 2 2 0 RNA binding Region RVT_1 PF00078.27 GBG73062.1 - 9.1e-35 120.2 0.2 3e-34 118.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73062.1 - 1.9e-20 73.1 0.8 2.9e-19 69.3 0.3 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73062.1 - 2.4e-19 69.2 0.7 6.4e-19 67.8 0.7 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73062.1 - 1.1e-15 57.8 0.0 2.6e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG73062.1 - 2e-12 47.0 0.1 4.3e-11 42.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG73062.1 - 0.0012 19.0 1.3 0.0022 18.2 0.1 2.2 2 0 0 2 2 2 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG73062.1 - 0.03 13.9 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase H_PPase PF03030.16 GBG73063.1 - 9.3e-166 553.2 28.5 1.2e-138 463.7 17.9 2.0 1 1 1 2 2 2 2 Inorganic H+ pyrophosphatase H_PPase PF03030.16 GBG73064.1 - 4.8e-183 610.3 27.1 4.5e-156 521.2 16.9 2.0 1 1 1 2 2 2 2 Inorganic H+ pyrophosphatase Retrotrans_gag PF03732.17 GBG73065.1 - 7.3e-05 23.0 1.2 0.0015 18.8 0.2 2.6 1 1 1 2 2 2 1 Retrotransposon gag protein Topo_Zn_Ribbon PF08272.11 GBG73065.1 - 0.069 12.8 2.7 0.071 12.8 0.1 2.4 3 0 0 3 3 3 0 Topoisomerase I zinc-ribbon-like CHASE9 PF17153.4 GBG73065.1 - 0.17 12.0 0.4 0.52 10.5 0.2 1.9 2 0 0 2 2 2 0 Periplasmic sensor domain, extracellular zf-CCHC PF00098.23 GBG73065.1 - 0.39 10.9 3.4 0.7 10.1 3.4 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG73066.1 - 1.6e-23 82.6 0.0 2.7e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73066.1 - 1.7e-20 73.2 0.0 3.3e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73066.1 - 8.8e-11 41.7 0.1 1.3e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cwf_Cwc_15 PF04889.12 GBG73066.1 - 1.3 8.7 8.5 2 8.1 8.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG73066.1 - 2.5 6.3 8.3 3.6 5.8 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG73066.1 - 2.9 6.0 10.5 3.8 5.6 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG73066.1 - 3.2 7.0 13.2 4.5 6.5 13.2 1.1 1 0 0 1 1 1 0 BUD22 H_PPase PF03030.16 GBG73067.1 - 3.5e-251 835.5 37.6 4.1e-251 835.2 37.6 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase H_PPase PF03030.16 GBG73069.1 - 4.9e-43 147.7 1.2 5.4e-43 147.6 1.2 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF3042 PF11240.8 GBG73069.1 - 0.64 10.1 2.4 1.4 8.9 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) PT-VENN PF04829.13 GBG73069.1 - 6.7 6.9 6.8 21 5.3 4.3 2.2 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif RVT_1 PF00078.27 GBG73070.1 - 1.4e-25 90.1 0.0 2.4e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG73070.1 - 2.4e-06 28.1 0.0 8.2e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73070.1 - 0.00012 22.6 0.1 0.00052 20.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease H_PPase PF03030.16 GBG73071.1 - 4.4e-33 114.8 0.3 4.9e-33 114.7 0.3 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Topo_Zn_Ribbon PF08272.11 GBG73072.1 - 0.083 12.6 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG73072.1 - 0.22 11.7 1.9 0.32 11.1 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle HTH_48 PF17906.1 GBG73073.1 - 0.033 14.3 0.1 0.071 13.2 0.1 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase UPF0114 PF03350.16 GBG73074.1 - 1.1e-35 122.4 2.5 1.1e-35 122.4 2.5 1.7 2 0 0 2 2 2 1 Uncharacterized protein family, UPF0114 RVT_1 PF00078.27 GBG73075.1 - 2.2e-25 89.5 0.0 3.7e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73075.1 - 4.4e-22 78.4 0.1 9.2e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73075.1 - 1.8e-13 50.3 0.0 4.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73075.1 - 3.9e-13 49.6 0.1 1.9e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG73075.1 - 3.8e-12 46.1 0.0 8.8e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG73075.1 - 0.00014 22.0 0.0 0.00035 20.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG73075.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like HrpB7 PF09486.10 GBG73076.1 - 0.001 19.5 12.3 0.001 19.5 12.3 2.1 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) Myb_DNA-binding PF00249.31 GBG73077.1 - 1.2e-05 25.4 0.7 2.9e-05 24.2 0.3 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG73077.1 - 6.1e-05 23.3 1.1 0.00013 22.3 1.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG73077.1 - 0.012 15.9 0.7 0.039 14.2 0.2 2.1 1 1 1 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG73077.1 - 0.016 15.3 1.1 0.029 14.5 1.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Zip PF02535.22 GBG73079.1 - 3.5 6.8 6.4 4.9 6.3 6.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RRN3 PF05327.11 GBG73079.1 - 5 5.5 13.7 7 5.1 13.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GIY-YIG PF01541.24 GBG73081.1 - 3.4e-05 24.0 0.2 0.00035 20.8 0.0 2.7 2 0 0 2 2 2 1 GIY-YIG catalytic domain Trypsin_2 PF13365.6 GBG73082.1 - 3.4e-16 60.5 0.2 8.9e-16 59.1 0.2 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GBG73082.1 - 2e-08 34.4 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 GBG73082.1 - 2.3e-05 24.6 0.0 6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GBG73082.1 - 0.031 14.1 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 GBG73082.1 - 0.052 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF4187 PF13821.6 GBG73083.1 - 0.00071 19.3 0.2 0.0019 17.9 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG73083.1 - 0.0026 18.0 3.0 0.0038 17.5 0.1 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein PDZ_3 PF17815.1 GBG73084.1 - 8.1e-09 35.5 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Indigoidine_A PF04227.12 GBG73085.1 - 1.1e-128 428.7 4.9 1.4e-128 428.3 4.9 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein GAIN_A PF18619.1 GBG73085.1 - 0.027 14.7 0.4 0.073 13.3 0.4 1.7 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A NmrA PF05368.13 GBG73086.1 - 1e-12 48.1 0.0 1.5e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GBG73086.1 - 2.8e-10 40.1 0.1 3.6e-08 33.2 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GBG73086.1 - 7.8e-09 35.7 0.1 1.3e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 GBG73086.1 - 1.2e-06 27.8 0.0 0.00055 19.1 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 GBG73086.1 - 3.1e-06 26.4 0.0 0.00023 20.3 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GBG73086.1 - 0.0066 15.6 0.1 0.066 12.4 0.0 2.4 3 1 1 4 4 4 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GBG73086.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NOP19 PF10863.8 GBG73087.1 - 0.057 13.3 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Nucleolar protein 19 RT_RNaseH PF17917.1 GBG73088.1 - 1.9e-23 82.7 0.0 3.5e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73088.1 - 5.9e-23 80.8 0.0 1.1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG73088.1 - 1e-08 35.6 0.0 2.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73088.1 - 1.7e-06 28.5 0.0 3.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG73088.1 - 8.5e-05 22.2 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG73088.1 - 0.0012 18.6 0.5 0.0052 16.6 0.3 1.9 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 GBG73088.1 - 0.0037 17.3 8.7 0.062 13.4 1.4 2.6 2 0 0 2 2 2 2 Zinc knuckle RVP PF00077.20 GBG73088.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Sporozoite_P67 PF05642.11 GBG73088.1 - 0.013 13.6 0.0 0.046 11.8 0.0 1.8 1 1 1 2 2 2 0 Sporozoite P67 surface antigen Integrase_H2C2 PF17921.1 GBG73088.1 - 0.049 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain Exo_endo_phos PF03372.23 GBG73090.1 - 8e-11 41.9 0.0 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 GBG73090.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain Exo_endo_phos_2 PF14529.6 GBG73091.1 - 0.004 17.0 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GBG73091.1 - 0.02 14.4 0.1 0.039 13.5 0.1 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family CDC45 PF02724.14 GBG73091.1 - 0.46 8.7 10.9 0.63 8.3 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG73091.1 - 1.7 7.3 8.5 2.5 6.8 8.5 1.2 1 0 0 1 1 1 0 Presenilin Merozoite_SPAM PF07133.11 GBG73091.1 - 7.8 6.4 20.4 12 5.9 20.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RT_RNaseH_2 PF17919.1 GBG73092.1 - 2.9e-31 107.4 0.0 4.8e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73092.1 - 8.4e-29 100.0 0.0 1.9e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73092.1 - 2.6e-12 46.7 0.1 4.9e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73092.1 - 0.00052 20.2 0.1 0.0011 19.2 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG73092.1 - 0.041 14.1 0.1 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain PHD_4 PF16866.5 GBG73093.1 - 0.03 14.4 0.7 0.12 12.5 0.0 2.1 2 1 1 3 3 3 0 PHD-finger RVT_1 PF00078.27 GBG73094.1 - 1e-28 100.4 0.1 1.8e-28 99.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73094.1 - 5.9e-24 84.0 0.0 1.4e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73094.1 - 7.4e-11 42.3 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG73094.1 - 1.7e-05 25.3 0.0 3.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG73094.1 - 0.0002 21.2 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73094.1 - 0.00026 21.5 0.0 0.0007 20.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG73094.1 - 0.039 14.2 0.0 0.22 11.8 0.0 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein DUF1758 PF05585.12 GBG73094.1 - 0.1 12.3 0.1 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 Putative peptidase (DUF1758) zf-CCHC_3 PF13917.6 GBG73094.1 - 0.44 10.6 8.8 0.022 14.7 2.7 2.0 2 0 0 2 2 2 0 Zinc knuckle Sina PF03145.16 GBG73095.1 - 9.4e-52 175.9 0.3 1.2e-51 175.6 0.3 1.1 1 0 0 1 1 1 1 Seven in absentia protein family DUF4729 PF15866.5 GBG73095.1 - 0.039 13.3 0.2 0.35 10.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4729) DUF1272 PF06906.11 GBG73095.1 - 0.1 12.7 6.0 0.26 11.4 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-TRAF PF02176.18 GBG73095.1 - 0.43 11.3 0.2 0.43 11.3 0.2 3.0 2 1 2 4 4 4 0 TRAF-type zinc finger Glyco_tranf_2_3 PF13641.6 GBG73097.1 - 1.3e-24 87.3 0.2 1.9e-24 86.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG73097.1 - 1.4e-21 77.4 2.6 1.4e-21 77.4 2.6 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG73097.1 - 1e-11 45.0 0.0 1.7e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GBG73097.1 - 5e-10 39.1 0.0 9.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 GBG73097.1 - 0.001 17.8 1.1 0.92 8.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase GRP PF07172.11 GBG73097.1 - 0.027 15.2 7.2 0.84 10.4 1.4 2.8 3 0 0 3 3 3 0 Glycine rich protein family Glyco_trans_2_3 PF13632.6 GBG73098.1 - 1.4e-21 77.3 2.6 1.4e-21 77.3 2.6 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GBG73098.1 - 8.7e-21 74.9 0.3 1.3e-20 74.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GBG73098.1 - 4.4e-09 36.0 0.0 7.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GBG73098.1 - 3.8e-07 30.1 0.0 6.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.15 GBG73098.1 - 0.00071 18.3 0.6 0.95 8.0 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase TPPK_C PF12555.8 GBG73098.1 - 0.032 14.3 0.3 0.032 14.3 0.3 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal WWE PF02825.20 GBG73099.1 - 2.6e-11 43.9 0.0 5.7e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 WWE domain PARP PF00644.20 GBG73099.1 - 7.8e-06 25.6 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PTS_2-RNA PF01885.16 GBG73099.1 - 0.024 14.7 0.0 0.068 13.2 0.0 1.8 2 1 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family RCR PF12273.8 GBG73100.1 - 0.14 12.8 1.0 0.34 11.6 0.0 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DDE_Tnp_4 PF13359.6 GBG73101.1 - 3.3e-31 108.1 0.0 6.1e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73101.1 - 3e-13 49.8 0.0 4.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG73101.1 - 0.00022 21.0 0.1 0.02 14.6 0.0 2.6 3 0 0 3 3 3 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG73101.1 - 0.044 14.2 0.1 0.62 10.5 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain Glyco_tranf_2_3 PF13641.6 GBG73104.1 - 1.3e-24 87.4 0.4 1.8e-24 86.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG73104.1 - 3.7e-22 79.2 4.6 3.7e-22 79.2 4.6 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG73104.1 - 1.4e-10 41.2 0.0 2.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GBG73104.1 - 9.1e-10 38.3 0.1 1.5e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 GBG73104.1 - 0.00035 19.3 3.0 0.25 9.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase MNHE PF01899.16 GBG73104.1 - 1.5 8.5 7.3 1.9 8.2 0.1 2.7 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit gag-asp_proteas PF13975.6 GBG73105.1 - 1.4e-05 25.6 0.1 3.4e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73105.1 - 0.0012 19.5 0.1 0.0031 18.1 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG73105.1 - 0.005 16.6 0.1 0.008 16.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73105.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG73105.1 - 0.031 13.9 0.3 0.062 13.0 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG73105.1 - 0.057 13.5 1.9 0.12 12.5 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG73107.1 - 4.5e-18 65.4 0.0 6.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73107.1 - 2.5e-06 27.2 0.0 4.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein WWE PF02825.20 GBG73108.1 - 6.9e-09 36.2 0.0 2.5e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 WWE domain PARP PF00644.20 GBG73108.1 - 1.3e-05 24.9 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PTS_2-RNA PF01885.16 GBG73108.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 1 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family V_ATPase_I PF01496.19 GBG73109.1 - 6.1 4.6 10.0 6.5 4.5 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_tranf_2_3 PF13641.6 GBG73110.1 - 3.1e-22 79.6 0.2 4.4e-22 79.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG73110.1 - 2.6e-21 76.5 3.7 4e-21 75.8 3.7 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG73110.1 - 3.3e-10 40.0 0.0 5.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GBG73110.1 - 3.7e-07 29.8 0.0 6.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 GBG73110.1 - 0.0022 16.7 5.1 0.16 10.5 4.8 2.2 2 0 0 2 2 2 2 Chitin synthase Cellulose_synt PF03552.14 GBG73110.1 - 0.083 11.4 0.8 0.11 10.9 0.8 1.1 1 0 0 1 1 1 0 Cellulose synthase RT_RNaseH_2 PF17919.1 GBG73111.1 - 3.1e-29 101.0 0.0 2.4e-14 53.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73111.1 - 4.6e-29 100.8 0.0 9e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73111.1 - 6.6e-26 91.2 0.1 1.2e-25 90.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73111.1 - 1.6e-14 53.8 0.0 3.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73111.1 - 4e-10 39.9 0.0 1.9e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG73111.1 - 0.0024 18.0 0.0 0.0065 16.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG73112.1 - 0.0012 19.2 2.0 0.0012 19.2 2.0 1.8 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Barttin PF15462.6 GBG73112.1 - 0.0097 15.7 0.7 0.015 15.1 0.7 1.2 1 0 0 1 1 1 1 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Myb_DNA-bind_6 PF13921.6 GBG73112.1 - 0.016 15.4 0.7 0.034 14.4 0.7 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG73112.1 - 0.08 13.2 0.7 0.21 11.8 0.7 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG73112.1 - 1.1 9.4 5.0 0.29 11.3 1.5 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG73113.1 - 1.9e-24 85.6 0.0 4.2e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73113.1 - 4.8e-24 84.6 0.0 1e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73113.1 - 1.9e-20 72.7 0.1 3.9e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG73113.1 - 9e-11 41.7 2.2 1.8e-10 40.7 0.1 2.4 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG73113.1 - 6.3e-09 35.7 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG73113.1 - 2.4e-07 30.9 0.1 8.4e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG73113.1 - 3.3e-07 30.9 0.0 5.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73113.1 - 1.5e-05 25.5 0.0 2.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73113.1 - 0.0037 17.0 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG73113.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG73116.1 - 5.1e-08 33.2 0.8 2e-07 31.3 0.5 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG73116.1 - 0.019 15.0 1.6 0.019 15.0 1.6 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG73117.1 - 1.3e-33 115.9 0.0 8.5e-33 113.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73117.1 - 2.5e-14 53.4 0.0 4.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG73117.1 - 1.1e-05 25.2 0.1 0.17 11.5 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG73117.1 - 0.025 14.9 0.3 0.83 10.1 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain HTH_48 PF17906.1 GBG73117.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase PARP PF00644.20 GBG73118.1 - 0.0019 17.8 0.9 2.3 7.8 0.0 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain FAM76 PF16046.5 GBG73118.1 - 0.0073 15.7 10.9 0.0099 15.3 10.9 1.1 1 0 0 1 1 1 1 FAM76 protein DUF1387 PF07139.11 GBG73118.1 - 0.045 13.5 12.2 0.064 13.0 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SpoIIP PF07454.11 GBG73118.1 - 0.12 11.8 5.6 0.16 11.4 5.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 GBG73118.1 - 0.23 10.2 6.2 0.26 10.0 6.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Rxt3 PF08642.10 GBG73118.1 - 0.49 11.2 2.7 1 10.1 2.7 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Sec62 PF03839.16 GBG73118.1 - 0.79 9.2 9.7 1.1 8.7 9.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3807 PF12720.7 GBG73118.1 - 1.1 9.5 12.0 1.7 8.9 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2149 PF09919.9 GBG73118.1 - 1.7 8.9 7.2 9.5 6.6 5.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DUF4834 PF16118.5 GBG73118.1 - 2.6 9.1 7.5 4.3 8.4 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 GBG73118.1 - 2.6 7.8 8.4 3.9 7.2 8.4 1.2 1 0 0 1 1 1 0 Connexin Folate_carrier PF01770.18 GBG73118.1 - 3.6 6.2 5.1 5 5.7 5.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier tRNA_synt_1c_R2 PF04557.15 GBG73118.1 - 4.9 8.2 21.2 62 4.6 20.2 2.3 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Eapp_C PF10238.9 GBG73118.1 - 7.9 6.5 14.3 25 4.9 14.5 1.7 2 1 0 2 2 2 0 E2F-associated phosphoprotein TFIIF_alpha PF05793.12 GBG73119.1 - 0.0035 16.0 16.1 0.0035 16.0 16.1 1.5 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDRGK PF09756.9 GBG73119.1 - 0.53 9.9 24.8 1.4 8.5 24.8 1.7 1 0 0 1 1 1 0 DDRGK domain Ldh_1_C PF02866.18 GBG73120.1 - 2e-43 148.2 0.0 2.5e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F-box-like PF12937.7 GBG73121.1 - 9.8e-05 22.2 0.0 0.00031 20.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GBG73121.1 - 0.00014 22.1 12.1 0.52 10.8 0.1 6.7 7 1 0 7 7 7 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG73121.1 - 0.002 17.9 0.0 0.0069 16.2 0.0 2.0 1 0 0 1 1 1 1 F-box domain DUF659 PF04937.15 GBG73125.1 - 4.3e-10 39.7 0.0 7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) YL1 PF05764.13 GBG73125.1 - 0.084 13.0 3.5 0.24 11.5 3.5 1.8 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GBG73125.1 - 5.6 6.6 7.8 0.43 10.3 2.2 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG73125.1 - 9.3 4.4 7.1 16 3.6 7.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Hexapep PF00132.24 GBG73126.1 - 1.7e-13 49.7 22.0 0.22 11.3 0.1 8.7 4 3 3 8 8 8 6 Bacterial transferase hexapeptide (six repeats) DUF963 PF06131.11 GBG73126.1 - 5.3e-13 48.1 79.7 0.0017 17.8 8.6 9.7 3 3 6 10 10 10 10 Schizosaccharomyces pombe repeat of unknown function (DUF963) MadM PF03818.13 GBG73126.1 - 2.2 8.2 4.7 7 6.6 0.4 2.6 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit Dimer_Tnp_hAT PF05699.14 GBG73127.1 - 0.00041 20.1 0.2 0.00078 19.2 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG73128.1 - 5.1e-05 23.2 0.0 9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG73129.1 - 0.0034 17.6 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Lamprin PF06403.11 GBG73129.1 - 2.4 8.1 13.0 5.3 7.0 13.0 1.6 1 0 0 1 1 1 0 Lamprin UPF0184 PF03670.13 GBG73130.1 - 0.46 10.9 2.5 0.76 10.2 0.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) UPF0242 PF06785.11 GBG73130.1 - 6.3 6.9 17.5 11 6.1 17.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Form-deh_trans PF09163.11 GBG73132.1 - 0.3 10.9 2.7 1.5 8.7 0.0 2.4 2 1 0 2 2 2 0 Formate dehydrogenase N, transmembrane Beta_helix PF13229.6 GBG73133.1 - 7.7e-05 22.6 0.9 0.0012 18.7 1.3 2.2 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG73133.1 - 0.29 11.7 28.8 0.35 11.4 0.2 7.1 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Peptidase_C48 PF02902.19 GBG73135.1 - 7.3e-23 81.5 0.0 1.1e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pkinase_Tyr PF07714.17 GBG73137.1 - 6.9e-33 114.0 0.0 1.5e-32 112.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG73137.1 - 7.8e-29 100.8 0.0 1.5e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG73137.1 - 0.00014 21.9 0.0 0.0014 18.6 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4834 PF16118.5 GBG73137.1 - 0.00061 20.7 0.8 0.18 12.8 1.1 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4834) Pkinase_fungal PF17667.1 GBG73137.1 - 0.022 13.5 2.0 1.7 7.4 0.0 2.4 2 1 0 2 2 2 0 Fungal protein kinase PA26 PF04636.13 GBG73137.1 - 0.077 11.9 1.7 0.12 11.3 1.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CLASP_N PF12348.8 GBG73139.1 - 5.3e-48 163.5 0.2 4.5e-39 134.3 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal HEAT_2 PF13646.6 GBG73139.1 - 1.6e-06 28.4 5.3 0.05 14.0 0.5 4.4 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 GBG73139.1 - 3.9e-05 23.5 13.2 0.076 13.3 0.0 7.2 8 0 0 8 8 8 1 HEAT repeat Ecm29 PF13001.7 GBG73139.1 - 0.0088 14.8 0.4 0.13 10.9 0.0 2.4 2 0 0 2 2 2 1 Proteasome stabiliser Adaptin_N PF01602.20 GBG73139.1 - 0.014 14.0 0.9 0.077 11.5 0.4 2.1 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 GBG73139.1 - 0.02 15.4 12.6 1.9 9.1 0.2 5.5 5 0 0 5 5 5 0 HEAT-like repeat ParcG PF10274.9 GBG73139.1 - 0.05 13.7 1.3 2.3 8.3 0.2 2.6 2 0 0 2 2 2 0 Parkin co-regulated protein MMS19_C PF12460.8 GBG73139.1 - 0.25 10.4 5.1 7.2 5.6 0.6 3.3 2 1 1 3 3 3 0 RNAPII transcription regulator C-terminal Nop14 PF04147.12 GBG73140.1 - 0.076 11.2 6.8 0.079 11.2 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG73140.1 - 0.21 11.0 9.4 0.25 10.7 9.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG73140.1 - 9.3 4.4 8.2 11 4.2 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG73141.1 - 2e-33 115.8 0.0 3.4e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73141.1 - 1.2e-29 102.3 0.0 2.8e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73141.1 - 5e-29 100.7 0.0 1.1e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73141.1 - 7.9e-18 64.3 0.2 7.9e-18 64.3 0.2 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73141.1 - 0.056 13.7 0.0 0.23 11.7 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG73142.1 - 0.0084 16.4 1.2 0.2 12.0 0.0 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein Phage_lysozyme PF00959.19 GBG73142.1 - 0.014 15.8 0.1 0.58 10.6 0.0 2.7 2 0 0 2 2 2 0 Phage lysozyme gpUL132 PF11359.8 GBG73142.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 RT_RNaseH_2 PF17919.1 GBG73143.1 - 3.7e-33 113.5 0.0 7.8e-33 112.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73143.1 - 2.7e-29 101.5 0.0 5.4e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73143.1 - 2.6e-14 53.1 0.1 5.2e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73143.1 - 2.3e-12 47.2 0.1 3.9e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG73143.1 - 2.5e-09 37.0 0.1 4.5e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG73144.1 - 1.1e-27 97.0 0.1 1.9e-27 96.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73144.1 - 2.2e-14 53.3 0.1 5.1e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73144.1 - 1.4e-10 41.4 0.0 3.8e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG73144.1 - 1.3e-08 35.2 0.0 3.3e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73144.1 - 1.7e-08 35.0 0.0 4.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG73144.1 - 2.1e-07 30.8 0.0 4.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73144.1 - 1.6e-05 24.7 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease CENP-K PF11802.8 GBG73144.1 - 0.0026 17.4 1.3 0.0047 16.5 1.3 1.3 1 0 0 1 1 1 1 Centromere-associated protein K AIP3 PF03915.13 GBG73144.1 - 0.0041 16.3 2.1 0.0068 15.5 2.1 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Chromo PF00385.24 GBG73144.1 - 0.0095 15.8 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG73144.1 - 0.13 12.5 0.1 0.37 11.0 0.1 1.9 1 0 0 1 1 1 0 H2C2 zinc finger TMEM247 PF15444.6 GBG73144.1 - 0.14 12.2 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 1 0 Transmembrane protein 247 TFIIA PF03153.13 GBG73144.1 - 1.2 9.1 15.0 2.6 7.9 15.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LPAM_2 PF13627.6 GBG73145.1 - 2.3 8.2 4.0 3.7 7.5 4.0 1.3 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site RVT_1 PF00078.27 GBG73146.1 - 5e-26 91.6 0.1 9.8e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73146.1 - 2.4e-21 76.0 0.0 5e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73146.1 - 1.9e-20 72.7 0.0 5.1e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73146.1 - 1.1e-14 54.3 0.1 1.1e-14 54.3 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG73146.1 - 0.0014 18.3 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) DUF2730 PF10805.8 GBG73146.1 - 0.022 14.8 0.2 0.12 12.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Retrotrans_gag PF03732.17 GBG73146.1 - 0.032 14.5 0.8 1.1 9.5 0.0 3.3 3 0 0 3 3 3 0 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG73146.1 - 0.16 12.0 3.6 11 6.1 0.2 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation CDC27 PF09507.10 GBG73146.1 - 0.29 10.5 5.9 0.59 9.5 5.9 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 IBR PF01485.21 GBG73146.1 - 3.6 7.9 7.9 18 5.7 1.1 2.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain COR PF16095.5 GBG73148.1 - 7.9e-11 42.1 0.0 2.8e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 GBG73148.1 - 1.9e-05 24.8 0.0 0.0053 17.0 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GBG73148.1 - 0.088 12.4 0.0 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 Ras family RVT_1 PF00078.27 GBG73149.1 - 4.2e-28 98.4 0.1 8e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73149.1 - 9.6e-14 51.2 0.0 4.4e-13 49.1 0.0 2.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73149.1 - 3.9e-10 40.0 0.0 8.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain COR PF16095.5 GBG73149.1 - 2e-09 37.5 0.0 4.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Snapin_Pallidin PF14712.6 GBG73149.1 - 1.6 9.2 7.7 0.56 10.6 0.1 3.3 3 0 0 3 3 3 0 Snapin/Pallidin Integrase_H2C2 PF17921.1 GBG73151.1 - 1.2e-17 63.7 0.1 2.4e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG73151.1 - 2.9e-15 56.4 1.3 8.1e-15 55.0 1.3 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73151.1 - 9.9e-12 45.1 0.0 2.7e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain WD40 PF00400.32 GBG73151.1 - 1.2e-09 38.6 6.7 1.5e-07 32.0 0.2 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat RT_RNaseH_2 PF17919.1 GBG73151.1 - 4.1e-05 23.5 0.1 9.4e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG73151.1 - 0.00051 20.2 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger LAP2alpha PF11560.8 GBG73151.1 - 0.0083 15.6 0.6 0.02 14.4 0.4 1.7 1 1 1 2 2 2 2 Lamina-associated polypeptide 2 alpha ANAPC4_WD40 PF12894.7 GBG73151.1 - 0.048 14.0 0.0 0.21 11.9 0.0 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 GBG73152.1 - 1.7e-33 116.0 0.1 2.6e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG73152.1 - 1.3e-07 31.4 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73152.1 - 3.4e-05 24.4 0.0 0.0001 22.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73152.1 - 0.00021 21.8 0.0 0.00057 20.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73152.1 - 0.00023 21.0 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DivIC PF04977.15 GBG73152.1 - 0.032 14.0 1.4 0.083 12.7 1.4 1.7 1 0 0 1 1 1 0 Septum formation initiator CCD48 PF15799.5 GBG73152.1 - 0.058 11.7 1.0 0.093 11.0 1.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 YabA PF06156.13 GBG73152.1 - 0.16 12.6 0.2 2.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 GBG73152.1 - 3.6 8.1 4.5 1.1 9.7 0.8 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ntox46 PF15538.6 GBG73155.1 - 0.045 13.7 0.0 21 5.1 0.0 3.8 3 2 2 5 5 5 0 Bacterial toxin 46 Retrotrans_gag PF03732.17 GBG73157.1 - 0.01 16.1 0.6 0.039 14.2 0.6 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein GRP PF07172.11 GBG73157.1 - 3.5 8.4 16.7 1.9 9.2 13.6 2.1 2 0 0 2 2 2 0 Glycine rich protein family Peptidase_C14 PF00656.22 GBG73158.1 - 6.1e-22 78.8 0.0 9.8e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Ntox46 PF15538.6 GBG73159.1 - 0.018 15.0 0.0 91 3.0 0.0 4.6 3 2 1 5 5 5 0 Bacterial toxin 46 TcdA_TcdB PF12919.7 GBG73160.1 - 0.02 14.2 0.1 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF659 PF04937.15 GBG73161.1 - 2.1e-08 34.1 0.1 8.5e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73161.1 - 9.2e-06 25.4 0.0 2.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Topo_Zn_Ribbon PF08272.11 GBG73162.1 - 0.06 13.0 2.0 0.067 12.9 0.3 2.0 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG73162.1 - 0.064 13.4 1.9 0.13 12.4 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle SICA_C PF12879.7 GBG73166.1 - 1.5 8.9 6.7 0.19 11.8 2.3 1.8 2 0 0 2 2 2 0 SICA C-terminal inner membrane domain Peptidase_C14 PF00656.22 GBG73168.1 - 9.1e-20 71.7 0.0 2.1e-19 70.5 0.0 1.6 1 1 0 1 1 1 1 Caspase domain RT_RNaseH_2 PF17919.1 GBG73170.1 - 2.2e-27 95.0 0.0 4.2e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73170.1 - 3.5e-24 85.1 0.0 6.5e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG73170.1 - 9.3e-06 25.5 3.2 1.6e-05 24.7 3.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG73170.1 - 0.019 14.8 4.1 0.032 14.1 4.1 1.3 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.14 GBG73170.1 - 1.5 7.0 7.5 2.3 6.4 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C14 PF00656.22 GBG73171.1 - 1.1e-20 74.6 0.2 2e-20 73.8 0.1 1.4 2 0 0 2 2 2 1 Caspase domain TetR_N PF00440.23 GBG73171.1 - 0.12 12.2 0.4 1.2 9.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Eno-Rase_FAD_bd PF07055.12 GBG73173.1 - 1.9 9.0 5.4 2.6 8.5 3.0 2.7 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain Vir_act_alpha_C PF10400.9 GBG73174.1 - 0.0031 18.1 1.0 0.011 16.4 1.0 1.9 1 1 0 1 1 1 1 Virulence activator alpha C-term RNA_pol_Rpb4 PF03874.16 GBG73174.1 - 0.2 12.0 0.1 0.37 11.1 0.0 1.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 Nop14 PF04147.12 GBG73175.1 - 1.9 6.6 17.7 2.5 6.2 17.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG73175.1 - 2.2 6.5 13.1 3.1 6.0 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG73175.1 - 4 6.7 19.7 5.9 6.1 19.7 1.2 1 0 0 1 1 1 0 BUD22 RT_RNaseH PF17917.1 GBG73176.1 - 5.3e-24 84.5 0.0 1.6e-23 83.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73176.1 - 1.2e-23 83.1 0.0 3e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73176.1 - 1.8e-18 66.4 0.7 3.8e-18 65.3 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG73176.1 - 7.2e-18 64.9 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73176.1 - 8.4e-06 26.0 0.0 7.3e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG73176.1 - 0.036 14.4 0.5 0.26 11.6 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein SNAD1 PF18744.1 GBG73176.1 - 0.036 13.9 0.2 0.26 11.1 0.0 2.4 3 0 0 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 1 zf-H2C2 PF09337.10 GBG73176.1 - 0.038 14.2 0.7 0.19 12.0 0.7 2.3 1 1 0 1 1 1 0 H2C2 zinc finger DUF2716 PF10898.8 GBG73176.1 - 0.57 10.6 3.5 0.42 11.0 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2716) CDC45 PF02724.14 GBG73179.1 - 0.00014 20.3 10.1 0.00016 20.1 10.1 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GBG73179.1 - 0.0026 17.3 23.3 0.0032 17.0 23.3 1.0 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG73179.1 - 0.028 12.6 25.8 0.035 12.3 25.8 1.0 1 0 0 1 1 1 0 Nop14-like family zf_C2H2_ZHX PF18387.1 GBG73179.1 - 0.078 12.6 0.9 12 5.6 0.2 2.7 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain SART-1 PF03343.13 GBG73179.1 - 0.092 11.3 17.2 0.12 10.9 17.2 1.1 1 0 0 1 1 1 0 SART-1 family Nop25 PF09805.9 GBG73179.1 - 0.12 12.8 19.0 0.16 12.4 19.0 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Tim54 PF11711.8 GBG73179.1 - 0.63 8.8 9.3 0.91 8.2 9.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 GBG73179.1 - 0.65 9.8 15.4 0.88 9.3 15.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3c_N PF05470.12 GBG73179.1 - 0.69 8.1 16.3 0.91 7.7 16.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mpp10 PF04006.12 GBG73179.1 - 0.82 8.0 29.5 1 7.7 29.5 1.0 1 0 0 1 1 1 0 Mpp10 protein CCSAP PF15748.5 GBG73179.1 - 1.2 9.2 11.2 2.2 8.4 11.2 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BUD22 PF09073.10 GBG73179.1 - 1.4 8.1 22.5 1.8 7.8 22.5 1.1 1 0 0 1 1 1 0 BUD22 Na_trans_assoc PF06512.13 GBG73179.1 - 2.7 8.2 21.4 3.6 7.8 21.4 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated NPR3 PF03666.13 GBG73179.1 - 3.1 6.5 5.9 3.8 6.2 5.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.6 GBG73179.1 - 3.2 6.4 8.9 4.1 6.1 8.9 1.1 1 0 0 1 1 1 0 Raftlin DUF5523 PF17661.1 GBG73179.1 - 3.9 7.1 23.6 5.8 6.5 23.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) V_ATPase_I PF01496.19 GBG73179.1 - 4.7 5.0 8.8 5.6 4.8 8.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TP53IP5 PF15331.6 GBG73179.1 - 5 7.2 5.3 8.1 6.5 5.3 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Paf1 PF03985.13 GBG73179.1 - 7.8 5.4 34.6 11 4.9 34.6 1.1 1 0 0 1 1 1 0 Paf1 Kisspeptin PF15152.6 GBG73181.1 - 0.6 10.9 2.3 0.8 10.5 0.8 2.0 2 0 0 2 2 2 0 Kisspeptin Myb_DNA-bind_4 PF13837.6 GBG73184.1 - 5.6e-06 26.7 2.4 4.5e-05 23.7 1.2 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG73184.1 - 0.0016 18.4 1.4 0.011 15.8 1.3 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG73184.1 - 0.021 15.1 1.3 0.037 14.3 0.2 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GST_C PF00043.25 GBG73185.1 - 1.8e-05 24.8 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GBG73185.1 - 0.016 15.2 0.3 0.025 14.6 0.3 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GBG73185.1 - 0.069 13.7 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RVT_1 PF00078.27 GBG73186.1 - 8.8e-15 54.8 0.0 1.7e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73186.1 - 4.2e-07 29.9 0.3 1.1e-06 28.6 0.3 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG73187.1 - 1.3e-16 60.9 0.2 2.4e-16 59.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73187.1 - 0.00037 20.2 0.0 0.00088 19.0 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Peptidase_C14 PF00656.22 GBG73189.1 - 4.4e-22 79.2 0.0 7.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Caspase domain RT_RNaseH PF17917.1 GBG73190.1 - 1.8e-11 44.3 0.0 2.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73190.1 - 0.039 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase BUD22 PF09073.10 GBG73190.1 - 0.23 10.7 15.0 0.32 10.3 15.0 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG73190.1 - 0.44 8.8 10.0 0.55 8.5 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG73190.1 - 1.3 7.2 13.9 1.6 6.8 13.9 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG73190.1 - 1.6 8.4 11.6 1.6 8.4 10.6 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG73190.1 - 1.6 8.1 13.0 2 7.8 13.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG73192.1 - 3.7 5.7 5.9 4.6 5.4 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C14 PF00656.22 GBG73193.1 - 2.2e-22 80.3 0.1 3.9e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 GBG73194.1 - 9.6e-21 74.9 0.0 2.2e-20 73.7 0.0 1.6 1 1 0 1 1 1 1 Caspase domain F-box-like PF12937.7 GBG73195.1 - 1.6e-05 24.7 1.1 3.2e-05 23.7 1.1 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GBG73195.1 - 0.00033 21.0 0.9 0.99 9.9 0.0 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG73195.1 - 0.00044 20.1 1.2 0.0019 18.0 0.2 2.3 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 GBG73195.1 - 0.016 15.3 0.5 5.4 7.3 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Tyr_Deacylase PF02580.16 GBG73196.1 - 3e-51 173.7 0.0 3.5e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase F-box PF00646.33 GBG73197.1 - 2.6e-07 30.3 4.2 3.1e-06 26.9 0.2 3.0 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 GBG73197.1 - 7.1e-05 22.6 0.4 7.1e-05 22.6 0.4 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GBG73197.1 - 0.11 12.9 0.0 0.42 11.1 0.0 2.0 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 GBG73199.1 - 4.7e-40 137.5 0.0 1.4e-39 135.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG73199.1 - 1.4e-39 136.0 0.0 2e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG73199.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 GBG73199.1 - 0.14 12.3 0.0 0.93 9.7 0.0 2.0 2 0 0 2 2 2 0 ABC1 family RT_RNaseH PF17917.1 GBG73200.1 - 3.5e-19 69.0 0.0 8.7e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73200.1 - 3.6e-19 68.6 0.0 8.2e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG73200.1 - 1.7e-07 31.7 0.0 5.1e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG73200.1 - 3.1e-05 23.6 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG73200.1 - 4.3e-05 24.1 0.0 0.0001 22.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG73200.1 - 0.00015 21.5 0.9 0.00029 20.6 0.9 1.3 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG73200.1 - 0.016 15.3 0.0 0.055 13.6 0.0 1.9 1 0 0 1 1 1 0 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG73200.1 - 0.024 14.9 0.0 0.077 13.3 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RVP PF00077.20 GBG73200.1 - 0.068 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Lamprin PF06403.11 GBG73200.1 - 9.4 6.2 9.5 19 5.2 9.5 1.5 1 0 0 1 1 1 0 Lamprin Peptidase_C13 PF01650.18 GBG73201.1 - 7e-99 330.5 0.0 1e-98 330.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family ANAPC10 PF03256.16 GBG73201.1 - 0.19 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) E7 PF00527.18 GBG73201.1 - 1.7 8.9 7.7 17 5.7 0.5 3.2 3 0 0 3 3 3 0 E7 protein, Early protein Ferritin PF00210.24 GBG73202.1 - 4.4e-18 65.6 0.4 5.7e-18 65.2 0.4 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin PF00210.24 GBG73203.1 - 8.5e-17 61.4 0.1 9.7e-16 58.0 0.1 2.0 1 1 0 1 1 1 1 Ferritin-like domain R3H PF01424.22 GBG73203.1 - 0.051 13.6 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 R3H domain DUF659 PF04937.15 GBG73204.1 - 4.7e-33 114.2 0.0 7.4e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73204.1 - 0.015 15.0 0.1 0.073 12.9 0.0 2.0 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Nop14 PF04147.12 GBG73207.1 - 0.00022 19.6 32.4 0.00027 19.3 32.4 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG73207.1 - 0.035 13.6 37.9 0.045 13.2 37.9 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG73207.1 - 0.072 11.9 8.0 0.086 11.6 8.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 GBG73207.1 - 0.36 10.1 31.1 0.43 9.9 31.1 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 GBG73207.1 - 0.93 8.8 28.5 1.4 8.3 28.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIIAH PF12685.7 GBG73207.1 - 1 9.2 7.0 1.6 8.5 7.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Dimer_Tnp_hAT PF05699.14 GBG73208.1 - 6.4e-13 48.3 1.5 8.8e-12 44.7 1.5 2.5 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region DBD_Tnp_Hermes PF10683.9 GBG73208.1 - 0.00014 21.5 0.1 0.00036 20.2 0.0 1.8 2 0 0 2 2 2 1 Hermes transposase DNA-binding domain Tet_JBP PF12851.7 GBG73208.1 - 0.18 11.1 0.9 1.4 8.2 0.0 2.0 1 1 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily RRM_1 PF00076.22 GBG73209.1 - 5.7e-18 64.5 0.0 8.7e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GBG73209.1 - 4.4e-06 26.5 2.3 9.6e-06 25.4 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG73209.1 - 0.0003 20.7 0.2 0.00062 19.7 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 GBG73209.1 - 0.00066 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_6 PF15288.6 GBG73209.1 - 0.047 13.5 0.4 0.12 12.3 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle Coagulin PF02035.15 GBG73209.1 - 0.077 12.9 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Coagulin RVT_1 PF00078.27 GBG73210.1 - 6.3e-19 68.4 0.0 2.6e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG73210.1 - 0.0041 17.4 10.7 0.015 15.6 0.2 4.4 4 0 0 4 4 4 2 Retrotransposon gag protein SWIB PF02201.18 GBG73211.1 - 2.7e-22 78.4 0.0 4.8e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain RT_RNaseH PF17917.1 GBG73212.1 - 5.7e-23 81.2 0.0 9.2e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73212.1 - 6.4e-23 80.7 0.0 1.1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3700 PF12481.8 GBG73214.1 - 2.5e-80 269.2 0.0 2.9e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Aluminium induced protein GATase_7 PF13537.6 GBG73214.1 - 3.4e-10 39.9 0.0 4.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GBG73214.1 - 7.8e-06 26.1 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF659 PF04937.15 GBG73215.1 - 3e-31 108.3 0.0 7.9e-31 107.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG73215.1 - 0.1 12.5 2.2 0.36 10.9 2.2 1.9 1 0 0 1 1 1 0 AT hook motif RVT_1 PF00078.27 GBG73218.1 - 2.8e-29 102.2 0.1 6e-29 101.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73218.1 - 1.7e-22 79.7 0.0 3.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73218.1 - 1.2e-21 76.6 0.0 2.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG73218.1 - 5.3e-07 29.5 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease MRP-L27 PF09809.9 GBG73218.1 - 1.5e-05 24.8 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Asp_protease_2 PF13650.6 GBG73218.1 - 2.6e-05 24.8 0.0 5.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73218.1 - 0.0032 18.0 0.0 0.0063 17.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73220.1 - 0.091 13.4 0.0 0.37 11.5 0.0 2.1 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG73221.1 - 3.3e-32 110.5 0.1 7.1e-32 109.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73221.1 - 1.1e-30 106.0 0.2 2.7e-30 104.8 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73221.1 - 5.8e-13 48.9 0.9 1.2e-12 47.9 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACT_5 PF13710.6 GBG73221.1 - 0.054 13.3 0.1 9.1 6.2 0.0 2.7 3 0 0 3 3 3 0 ACT domain rve_3 PF13683.6 GBG73221.1 - 0.13 12.1 0.4 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain RVT_1 PF00078.27 GBG73222.1 - 7.2e-25 87.8 0.2 2e-24 86.4 0.2 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73222.1 - 1e-06 28.7 0.0 3.1e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73222.1 - 1e-05 25.7 0.0 2.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG73222.1 - 0.0057 16.4 0.0 0.1 12.4 0.0 2.2 1 1 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG73222.1 - 0.013 15.7 3.1 0.02 15.2 0.5 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein ZapB PF06005.12 GBG73222.1 - 0.014 15.8 1.2 0.098 13.1 0.1 3.0 2 0 0 2 2 2 0 Cell division protein ZapB Asp_protease PF09668.10 GBG73222.1 - 0.027 14.3 0.1 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 Aspartyl protease DUF2202 PF09968.9 GBG73222.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) ABC_tran_CTD PF16326.5 GBG73222.1 - 2.9 8.2 5.8 1.7 8.9 0.3 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF4407 PF14362.6 GBG73222.1 - 5.8 6.2 9.6 0.096 12.0 2.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GATA PF00320.27 GBG73223.1 - 0.0023 17.5 4.4 0.098 12.3 1.3 2.8 1 1 2 3 3 3 3 GATA zinc finger Toxin_3 PF00537.18 GBG73223.1 - 0.36 11.0 7.2 2.4 8.4 7.2 2.5 1 1 0 1 1 1 0 Scorpion toxin-like domain DUF3995 PF13160.6 GBG73223.1 - 0.4 11.0 3.7 7.6 6.9 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) RVT_1 PF00078.27 GBG73226.1 - 9.3e-09 35.1 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73226.1 - 4.5e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73226.1 - 0.0048 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NOB1_Zn_bind PF08772.11 GBG73226.1 - 0.17 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-CCHC_2 PF13696.6 GBG73227.1 - 0.42 10.5 1.3 0.63 9.9 1.3 1.3 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG73228.1 - 1.6e-07 31.8 0.1 6.2e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73228.1 - 0.0003 21.4 0.0 0.00092 19.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG73228.1 - 0.081 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG73229.1 - 1.2e-45 153.6 0.0 3.4e-24 84.8 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73229.1 - 4.3e-29 100.9 0.0 4.8e-15 55.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73229.1 - 1.8e-23 83.3 0.1 3.1e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73229.1 - 4.3e-09 36.6 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain SWIRM PF04433.17 GBG73229.1 - 3.1e-05 24.2 0.4 0.0001 22.6 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain DUF1564 PF07600.11 GBG73229.1 - 0.05 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG73230.1 - 9.9e-37 126.6 0.0 1.6e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73230.1 - 1.8e-29 101.7 0.0 4.4e-29 100.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73230.1 - 2.5e-28 98.4 0.0 5.4e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG73230.1 - 0.00031 20.5 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73230.1 - 0.042 14.5 0.0 0.085 13.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Phage_GPO PF05929.11 GBG73230.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase SelB-wing_1 PF09105.10 GBG73230.1 - 0.54 10.3 2.0 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Integrase_H2C2 PF17921.1 GBG73231.1 - 2.1e-17 63.0 0.1 4.3e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG73231.1 - 6.5e-08 32.4 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73231.1 - 6.6e-08 32.8 0.0 2.2e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG73231.1 - 4.4e-06 27.2 0.0 9.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73231.1 - 4.7e-06 26.4 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73231.1 - 0.00015 22.2 0.0 0.00036 21.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG73233.1 - 5.5e-14 52.0 0.0 1.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF4611 PF15387.6 GBG73233.1 - 0.039 14.2 0.3 0.039 14.2 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) zf-H2C2 PF09337.10 GBG73233.1 - 0.044 14.0 0.4 0.097 12.9 0.4 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Macoilin PF09726.9 GBG73233.1 - 0.13 10.8 3.1 0.23 10.0 3.1 1.4 1 0 0 1 1 1 0 Macoilin family RT_RNaseH_2 PF17919.1 GBG73234.1 - 8.4e-60 199.0 0.0 2.2e-35 120.7 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73234.1 - 4e-48 162.0 0.0 1.1e-27 96.3 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73234.1 - 5e-26 91.6 0.2 7e-18 64.9 0.0 3.2 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG73234.1 - 0.0046 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4187 PF13821.6 GBG73234.1 - 0.039 13.7 0.4 0.16 11.8 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RT_RNaseH_2 PF17919.1 GBG73235.1 - 8e-07 29.0 0.1 2.8e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73235.1 - 1.1e-05 25.6 0.1 4.6e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Rox3 PF08633.10 GBG73235.1 - 0.0057 17.0 0.4 0.41 10.9 0.2 2.2 2 0 0 2 2 2 1 Rox3 mediator complex subunit PDEase_II PF02112.15 GBG73235.1 - 0.046 12.8 0.1 0.065 12.3 0.1 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II MscS_TM PF12794.7 GBG73235.1 - 3.6 6.3 4.6 4.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 RT_RNaseH_2 PF17919.1 GBG73236.1 - 4.4e-31 106.9 0.0 4e-16 58.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73236.1 - 7.8e-30 103.3 0.0 1.5e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73236.1 - 3.5e-28 98.6 0.1 6.3e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73236.1 - 7.3e-12 45.2 0.1 1.5e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73236.1 - 0.00017 21.8 0.1 0.0004 20.6 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG73237.1 - 1.1e-22 80.3 0.0 3.1e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73237.1 - 4.3e-22 78.0 0.0 1.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73237.1 - 1.3e-11 44.7 0.0 3.1e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG73237.1 - 0.0037 17.0 0.0 0.015 15.1 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG73237.1 - 0.066 13.5 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG73237.1 - 0.21 11.5 1.5 0.35 10.8 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle PPP4R2 PF09184.11 GBG73238.1 - 4.1 6.9 19.3 4.8 6.7 19.3 1.1 1 0 0 1 1 1 0 PPP4R2 DUF659 PF04937.15 GBG73239.1 - 3.5e-15 56.2 0.2 9.6e-15 54.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) zf-C2H2_4 PF13894.6 GBG73239.1 - 0.085 13.7 0.4 0.42 11.6 0.4 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger Integrase_H2C2 PF17921.1 GBG73240.1 - 2.8e-17 62.6 0.1 5.1e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain TRAPP PF04051.16 GBG73240.1 - 8.5e-14 51.5 0.0 3.2e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Transport protein particle (TRAPP) component rve PF00665.26 GBG73240.1 - 0.00024 21.3 0.0 0.00051 20.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG73241.1 - 7.4e-28 96.5 0.0 1.7e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73241.1 - 4.3e-25 88.0 0.1 9.1e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73241.1 - 1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rhamno_transf PF11316.8 GBG73241.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase PSP PF04046.16 GBG73241.1 - 0.16 11.8 0.0 27 4.7 0.0 2.8 2 0 0 2 2 2 0 PSP Phage_GPO PF05929.11 GBG73241.1 - 1.1 8.8 6.1 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG73242.1 - 1.6e-35 121.1 0.0 4e-35 119.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73242.1 - 1e-29 102.9 0.6 6e-29 100.4 0.0 2.7 4 0 0 4 4 4 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73242.1 - 4.1e-26 91.9 0.0 7.4e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG73242.1 - 4.3e-05 23.3 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73242.1 - 0.016 15.8 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73242.1 - 0.016 15.8 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease FANCF PF11107.8 GBG73242.1 - 0.02 14.1 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Tho1_MOS11_C PF18592.1 GBG73242.1 - 0.067 13.0 1.2 0.26 11.1 1.2 2.0 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain Vir_act_alpha_C PF10400.9 GBG73242.1 - 0.11 13.2 1.6 0.58 10.9 0.4 2.6 2 0 0 2 2 2 0 Virulence activator alpha C-term CENP-Q PF13094.6 GBG73242.1 - 0.51 10.5 4.8 1.3 9.2 4.8 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Phage_GPO PF05929.11 GBG73242.1 - 4.1 7.0 5.3 7.9 6.0 0.0 3.0 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIC PF04977.15 GBG73242.1 - 6.2 6.7 6.9 26 4.7 6.9 2.1 1 0 0 1 1 1 0 Septum formation initiator Retrotrans_gag PF03732.17 GBG73243.1 - 0.0099 16.1 1.1 0.049 13.9 0.1 2.5 2 1 1 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG73244.1 - 7.1e-19 67.7 0.0 2.4e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73244.1 - 7.3e-17 61.6 0.0 3.8e-16 59.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG73244.1 - 0.00012 22.6 0.0 0.00028 21.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG73244.1 - 0.00034 20.2 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG73244.1 - 0.00058 20.4 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SPAM PF02090.15 GBG73244.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein RVP PF00077.20 GBG73244.1 - 0.088 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG73245.1 - 4e-27 95.2 0.1 6.7e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73245.1 - 2.7e-10 40.2 0.0 8e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NPV_P10 PF05531.12 GBG73245.1 - 0.19 12.2 2.1 1.2 9.6 1.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-CCHC_3 PF13917.6 GBG73246.1 - 0.0002 21.3 0.9 0.00047 20.1 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle RseA_C PF03873.13 GBG73246.1 - 0.3 11.3 0.2 0.3 11.3 0.2 3.0 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain zf-CCHC PF00098.23 GBG73246.1 - 1 9.5 3.7 1.8 8.8 3.7 1.4 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG73247.1 - 4.9e-06 27.0 0.1 1.4e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73247.1 - 1.2e-05 25.9 0.0 3.8e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG73247.1 - 0.089 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73248.1 - 6.8e-07 29.1 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73248.1 - 9.6e-07 29.3 0.0 5.1e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73248.1 - 9.8e-06 26.1 0.0 3.1e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG73248.1 - 0.036 14.3 0.8 0.078 13.3 0.1 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein tRNA-synt_2 PF00152.20 GBG73250.1 - 1.2e-80 270.9 0.9 1.5e-67 227.9 0.2 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GBG73250.1 - 9.9e-09 35.1 0.0 3e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain WHEP-TRS PF00458.20 GBG73250.1 - 3.7e-08 33.4 6.2 8.1e-08 32.3 6.2 1.5 1 0 0 1 1 1 1 WHEP-TRS domain RNA_pol_Rpb2_45 PF10385.9 GBG73250.1 - 0.011 16.0 0.3 0.049 13.9 0.2 2.2 1 1 0 1 1 1 0 RNA polymerase beta subunit external 1 domain tRNA-synt_2d PF01409.20 GBG73250.1 - 0.018 14.6 0.1 0.089 12.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Lip_A_acyltrans PF03279.13 GBG73250.1 - 0.077 12.2 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase YhfZ_C PF14503.6 GBG73250.1 - 0.13 11.8 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 YhfZ C-terminal domain RVT_1 PF00078.27 GBG73251.1 - 1.2e-21 77.2 0.0 2.3e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73251.1 - 1e-15 57.6 0.3 3.3e-15 55.9 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG73251.1 - 6.4e-13 48.6 0.0 2e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73251.1 - 5.7e-09 36.2 0.0 1.7e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG73251.1 - 2.2e-05 24.7 0.0 0.00054 20.2 0.0 2.6 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG73251.1 - 0.00024 21.3 2.4 0.0015 18.8 0.1 3.6 3 0 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG73252.1 - 4.4e-28 98.3 0.0 8.7e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73252.1 - 1.4e-15 57.1 0.0 3.4e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73252.1 - 0.00012 22.3 0.0 0.00027 21.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73252.1 - 0.01 16.0 0.0 0.043 14.0 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain DUF2385 PF09539.10 GBG73252.1 - 0.075 13.6 0.2 1 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Chromo PF00385.24 GBG73252.1 - 0.27 11.2 0.8 0.52 10.3 0.0 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain TFIIA PF03153.13 GBG73253.1 - 6.5e-05 23.1 37.0 0.018 15.1 12.8 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Pex24p PF06398.11 GBG73253.1 - 0.00032 19.8 2.8 0.00046 19.3 2.8 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DNA_pol_phi PF04931.13 GBG73253.1 - 0.00083 17.6 54.6 0.00088 17.5 13.8 2.4 2 0 0 2 2 2 2 DNA polymerase phi Paf1 PF03985.13 GBG73253.1 - 0.0029 16.7 3.5 0.0029 16.7 3.5 2.4 3 0 0 3 3 3 2 Paf1 PPP4R2 PF09184.11 GBG73253.1 - 0.018 14.6 30.6 0.037 13.6 12.0 2.4 2 0 0 2 2 2 0 PPP4R2 SUR7 PF06687.12 GBG73253.1 - 0.022 14.4 0.4 0.022 14.4 0.4 1.8 2 0 0 2 2 2 0 SUR7/PalI family PET PF06297.14 GBG73253.1 - 0.081 13.2 0.2 0.18 12.1 0.2 1.6 1 0 0 1 1 1 0 PET Domain Pho86 PF11124.8 GBG73253.1 - 0.21 11.0 11.2 0.13 11.7 6.5 2.0 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 DUF2457 PF10446.9 GBG73253.1 - 1.2 8.2 67.4 2.3 7.3 24.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Asp_protease_2 PF13650.6 GBG73255.1 - 0.011 16.4 0.0 0.021 15.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG73256.1 - 0.07 13.4 0.1 0.57 10.5 0.0 2.5 3 0 0 3 3 3 0 Retrotransposon gag protein DUF2385 PF09539.10 GBG73256.1 - 0.089 13.3 0.4 1.4 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) DUF4692 PF15763.5 GBG73256.1 - 1.6 9.2 8.1 0.93 9.9 0.5 2.7 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF659 PF04937.15 GBG73257.1 - 1.1e-29 103.3 0.0 1.8e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73257.1 - 5.7e-08 32.4 0.3 1.4e-07 31.2 0.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG73258.1 - 4.6e-34 117.9 0.0 9.3e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73258.1 - 2.1e-31 107.9 0.0 4.8e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73258.1 - 9.9e-31 106.1 0.1 1.9e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG73258.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH PF17917.1 GBG73259.1 - 2.4e-26 92.0 0.1 4.9e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73259.1 - 3.8e-26 92.0 0.0 6.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73259.1 - 1.1e-19 70.3 0.0 2.7e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73259.1 - 1.3e-18 66.8 0.1 3.2e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73259.1 - 2.4e-15 56.8 0.0 9.7e-15 54.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG73259.1 - 0.024 14.9 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger TrmB PF01978.19 GBG73259.1 - 0.14 12.1 0.4 11 6.0 0.1 3.1 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB SR-25 PF10500.9 GBG73259.1 - 3.3 7.3 9.4 6.4 6.3 9.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RT_RNaseH_2 PF17919.1 GBG73260.1 - 1.7e-33 114.7 0.0 3.8e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73260.1 - 2.2e-21 76.1 0.0 6.4e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73260.1 - 8.5e-20 71.2 0.0 1.7e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73260.1 - 5.3e-12 46.0 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG73261.1 - 1.8e-16 60.0 0.2 3.4e-16 59.1 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG73261.1 - 2.1e-06 28.2 0.0 4.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73261.1 - 2.9e-05 24.6 0.0 5.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG73261.1 - 0.00086 19.5 0.3 0.002 18.3 0.1 1.8 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG73261.1 - 0.0034 17.2 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73261.1 - 0.028 14.2 0.2 0.12 12.2 0.2 2.1 1 1 0 1 1 1 0 Aspartyl protease DUF2862 PF11061.8 GBG73261.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) gag-asp_proteas PF13975.6 GBG73262.1 - 5.6e-08 33.2 0.0 2e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73262.1 - 1.1e-07 32.4 0.0 2.9e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73262.1 - 1.5e-06 28.0 0.0 3.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG73262.1 - 7.4e-06 25.6 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG73262.1 - 2.5e-05 24.0 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease FAT PF02259.23 GBG73262.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 FAT domain rve PF00665.26 GBG73263.1 - 1.2e-10 41.6 0.2 5e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG73263.1 - 9.2e-09 35.5 16.5 0.023 15.0 0.1 6.4 6 1 1 7 7 7 4 Retrotransposon gag protein Chromo PF00385.24 GBG73263.1 - 0.00018 21.3 0.1 0.00042 20.2 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG73263.1 - 0.00024 20.8 13.9 0.021 14.6 2.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4187) DUF2730 PF10805.8 GBG73263.1 - 0.0098 16.0 1.5 1.8 8.7 0.2 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2730) SlyX PF04102.12 GBG73263.1 - 3.8 8.2 16.9 0.36 11.5 0.7 4.8 4 1 0 4 4 4 0 SlyX DUF1664 PF07889.12 GBG73263.1 - 8.3 6.5 11.4 0.96 9.5 0.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) RVP_2 PF08284.11 GBG73264.1 - 0.00058 19.6 0.0 0.0019 18.0 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73264.1 - 0.0031 17.3 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG73264.1 - 0.029 15.0 0.0 0.32 11.7 0.0 2.6 3 0 0 3 3 3 0 Aspartyl protease DUF2385 PF09539.10 GBG73264.1 - 0.076 13.6 0.1 1.6 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) RVT_1 PF00078.27 GBG73265.1 - 1.6e-28 99.8 0.1 3.8e-28 98.5 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73265.1 - 1.9e-23 82.4 0.0 6.3e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73265.1 - 1.7e-22 79.7 0.0 4.8e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73265.1 - 5.3e-19 68.1 0.4 2.6e-18 65.9 0.2 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG73265.1 - 4.4e-06 27.3 0.0 1.4e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73265.1 - 6e-05 23.5 0.0 0.00018 22.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG73265.1 - 0.0063 16.3 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73265.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG73266.1 - 1.4e-30 105.3 0.0 2.5e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73266.1 - 2.4e-29 102.4 0.1 3.9e-29 101.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73266.1 - 9.8e-27 93.3 0.0 1.7e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NAAA-beta PF15508.6 GBG73266.1 - 0.029 14.7 0.0 0.74 10.2 0.0 2.7 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Integrase_H2C2 PF17921.1 GBG73266.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain Herpes_UL25 PF01499.16 GBG73267.1 - 0.33 9.4 10.1 0.34 9.4 10.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family LMBR1 PF04791.16 GBG73267.1 - 0.9 8.4 5.8 0.97 8.3 5.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Selenoprotein_S PF06936.11 GBG73267.1 - 1.9 8.2 17.8 2.2 8.1 17.8 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF3629 PF12302.8 GBG73267.1 - 2.3 7.6 9.2 2.8 7.3 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) PA26 PF04636.13 GBG73267.1 - 2.6 6.9 12.2 2.9 6.7 12.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4407 PF14362.6 GBG73267.1 - 5.5 6.2 10.4 6.3 6.1 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5401 PF17380.2 GBG73267.1 - 5.6 4.9 23.5 6.5 4.7 23.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RT_RNaseH PF17917.1 GBG73270.1 - 3.1e-09 37.0 0.0 1e-07 32.1 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73270.1 - 8.7e-07 28.9 0.0 2.3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73271.1 - 8.4e-22 77.4 0.5 2.3e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73271.1 - 4.6e-21 74.7 0.0 1.6e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73271.1 - 1.8e-08 34.2 0.1 3.9e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V_ATPase_I PF01496.19 GBG73271.1 - 0.043 11.7 5.9 0.061 11.3 5.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BORG_CEP PF14957.6 GBG73271.1 - 1.2 10.4 4.0 2.6 9.2 4.0 1.5 1 0 0 1 1 1 0 Cdc42 effector Presenilin PF01080.17 GBG73271.1 - 1.4 7.6 3.4 2 7.1 3.4 1.2 1 0 0 1 1 1 0 Presenilin Cytadhesin_P30 PF07271.11 GBG73271.1 - 8.9 5.8 6.7 15 5.0 6.7 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF659 PF04937.15 GBG73272.1 - 3.3e-37 127.7 0.0 2.5e-36 124.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) zf-C2HE PF16278.5 GBG73272.1 - 0.022 15.2 1.0 0.06 13.8 1.0 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger rve PF00665.26 GBG73273.1 - 8.6e-27 93.7 0.2 2.4e-14 53.6 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG73273.1 - 4.9e-19 68.2 0.1 9.2e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG73273.1 - 0.0015 18.2 0.0 2.1 8.0 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1564) NHase_beta PF02211.15 GBG73273.1 - 0.0074 16.3 0.3 8.6 6.3 0.1 3.5 3 0 0 3 3 3 1 Nitrile hydratase beta subunit TOBE_2 PF08402.10 GBG73273.1 - 0.0094 16.1 0.2 6.4 7.0 0.0 2.6 2 0 0 2 2 2 2 TOBE domain rve_3 PF13683.6 GBG73273.1 - 0.013 15.2 0.2 2.3 8.1 0.0 3.1 2 0 0 2 2 2 0 Integrase core domain DUF3677 PF12432.8 GBG73273.1 - 0.068 13.5 0.1 0.25 11.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Peptidase_C39 PF03412.15 GBG73273.1 - 0.082 12.7 0.4 14 5.5 0.1 2.4 2 0 0 2 2 2 0 Peptidase C39 family Retrotrans_gag PF03732.17 GBG73273.1 - 0.086 13.1 0.1 0.28 11.5 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein U1snRNP70_N PF12220.8 GBG73273.1 - 0.95 10.1 8.8 13 6.5 0.2 4.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RT_RNaseH_2 PF17919.1 GBG73274.1 - 4e-25 87.8 0.0 1.7e-24 85.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73274.1 - 3.3e-21 75.5 0.0 7e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1427 PF07235.11 GBG73274.1 - 0.0025 17.7 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1427) TnsE_C PF18623.1 GBG73274.1 - 0.071 13.0 0.1 7.2 6.5 0.0 2.3 2 0 0 2 2 2 0 TnsE C-terminal domain PYC_OADA PF02436.18 GBG73274.1 - 0.21 11.3 0.7 4.1 7.1 0.1 2.4 1 1 1 2 2 2 0 Conserved carboxylase domain DUF572 PF04502.13 GBG73274.1 - 4.6 6.8 12.2 1.5 8.3 9.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) V-ATPase_G_2 PF16999.5 GBG73274.1 - 5.2 7.5 17.0 0.56 10.6 0.7 3.2 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit Retrotrans_gag PF03732.17 GBG73276.1 - 0.0024 18.1 0.0 0.012 15.9 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein SlyX PF04102.12 GBG73276.1 - 0.011 16.3 0.7 0.011 16.3 0.7 4.0 3 1 1 4 4 4 0 SlyX TRPM_tetra PF16519.5 GBG73276.1 - 0.031 14.4 4.3 1.8 8.7 0.1 3.6 3 1 1 4 4 4 0 Tetramerisation domain of TRPM PTS_IIA PF02255.16 GBG73276.1 - 8.4 6.5 14.1 0.92 9.6 2.3 3.3 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit RT_RNaseH_2 PF17919.1 GBG73277.1 - 4.5e-30 103.6 1.2 8.8e-30 102.7 0.2 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73277.1 - 7.3e-30 103.4 1.0 1.2e-29 102.7 0.3 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG73277.1 - 0.0069 16.3 1.8 0.016 15.2 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG73277.1 - 0.044 14.0 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG73278.1 - 1.4e-26 93.4 0.1 2.5e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73278.1 - 5.6e-18 64.8 0.3 1.7e-17 63.3 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG73278.1 - 6.2e-16 58.6 0.0 2.5e-15 56.6 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73278.1 - 2.6e-10 40.2 0.0 1e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73278.1 - 1.8e-09 37.8 0.2 1e-08 35.4 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG73278.1 - 4.3e-05 23.3 0.0 9.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73278.1 - 4.6e-05 24.0 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73278.1 - 0.00025 21.5 0.0 0.0007 20.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG73278.1 - 0.019 15.2 7.3 0.089 13.1 0.2 4.1 3 0 0 3 3 3 0 Retrotransposon gag protein DUF421 PF04239.12 GBG73278.1 - 0.21 11.3 1.6 0.22 11.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF421) ThiS PF02597.20 GBG73278.1 - 0.21 12.2 0.4 12 6.6 0.2 2.9 2 0 0 2 2 2 0 ThiS family CBP4 PF07960.11 GBG73278.1 - 1.3 8.9 4.1 3.4 7.5 4.1 1.7 1 0 0 1 1 1 0 CBP4 Phage_lysozyme PF00959.19 GBG73279.1 - 0.059 13.8 0.0 0.24 11.9 0.0 2.0 1 0 0 1 1 1 0 Phage lysozyme DBINO PF13892.6 GBG73279.1 - 0.11 12.8 12.6 0.3 11.5 12.6 1.7 1 0 0 1 1 1 0 DNA-binding domain RT_RNaseH_2 PF17919.1 GBG73280.1 - 1e-25 89.6 0.0 2.4e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73280.1 - 1.2e-21 77.0 0.0 2.7e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73280.1 - 4.3e-19 68.4 0.4 9.7e-19 67.2 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG73280.1 - 3e-17 62.9 0.0 4.5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73280.1 - 9.3e-09 35.5 0.0 2.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG73280.1 - 0.096 12.9 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG73281.1 - 4.2e-19 68.9 0.1 8.3e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG73281.1 - 2.9e-08 34.2 0.0 9.7e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73281.1 - 3.1e-07 30.2 0.0 7.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73281.1 - 4.3e-07 30.4 0.0 1.4e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG73281.1 - 1.5e-06 28.3 0.9 0.0028 17.9 0.0 3.2 2 0 0 2 2 2 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG73281.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease GIT_CC PF16559.5 GBG73281.1 - 0.11 12.3 1.4 0.34 10.8 0.1 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CCDC84 PF14968.6 GBG73281.1 - 0.67 9.5 2.4 1.1 8.8 2.4 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 DUF659 PF04937.15 GBG73282.1 - 8.4e-26 90.6 0.0 1.5e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73282.1 - 5.6e-09 35.7 0.1 1.2e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region rve PF00665.26 GBG73284.1 - 4.5e-32 110.7 0.0 9.7e-15 54.8 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG73284.1 - 9e-30 102.7 0.0 2.3e-29 101.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73284.1 - 1.3e-27 96.8 0.1 4e-27 95.2 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73284.1 - 1.1e-26 93.2 0.1 2.9e-26 91.8 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73284.1 - 5.6e-17 61.6 2.5 9.7e-13 48.0 0.1 3.6 3 0 0 3 3 3 2 Integrase zinc binding domain DUF659 PF04937.15 GBG73284.1 - 0.0023 17.8 0.2 0.0023 17.8 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) zf-H2C2 PF09337.10 GBG73284.1 - 0.0027 17.9 0.1 0.011 15.9 0.0 2.3 2 0 0 2 2 1 1 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG73284.1 - 0.0048 16.8 0.5 0.014 15.3 0.5 1.8 1 0 0 1 1 1 1 Zinc knuckle Cys_rich_CPXG PF14255.6 GBG73284.1 - 0.016 15.1 1.5 5.3 7.0 0.4 3.1 2 0 0 2 2 2 0 Cysteine-rich CPXCG AT_hook PF02178.19 GBG73284.1 - 0.18 11.8 3.3 0.63 10.1 3.3 2.0 1 0 0 1 1 1 0 AT hook motif zf-CCHC PF00098.23 GBG73284.1 - 2.3 8.5 4.7 7.2 6.9 4.7 2.0 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG73285.1 - 6e-56 189.4 3.0 1.7e-28 99.6 0.1 3.1 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73285.1 - 9.1e-28 96.2 0.1 4.3e-27 94.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73285.1 - 3.1e-22 78.4 2.8 6.6e-18 64.6 0.2 3.1 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG73285.1 - 7.7e-15 55.1 0.0 2.2e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG73285.1 - 3e-12 46.9 0.0 0.00011 22.7 0.0 4.0 3 0 0 3 3 3 3 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73285.1 - 1.8e-09 38.1 0.0 0.0086 16.7 0.0 3.9 3 0 0 3 3 3 3 Aspartyl protease Retrotrans_gag PF03732.17 GBG73285.1 - 8.3e-07 29.2 5.8 0.01 16.1 0.1 4.0 4 0 0 4 4 4 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG73285.1 - 1.2e-05 25.1 0.0 0.37 10.6 0.0 3.3 3 0 0 3 3 3 2 Retroviral aspartyl protease DUF1758 PF05585.12 GBG73285.1 - 1.9e-05 24.5 0.3 0.29 10.9 0.0 2.9 3 0 0 3 3 3 2 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG73285.1 - 0.00029 20.6 0.0 2.8 7.8 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease zf-H2C2 PF09337.10 GBG73285.1 - 0.0015 18.7 0.0 0.0015 18.7 0.0 2.7 3 0 0 3 3 3 1 H2C2 zinc finger rve PF00665.26 GBG73285.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG73286.1 - 3.7e-36 124.7 0.0 6.4e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73286.1 - 2.3e-30 104.6 0.0 5.4e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73286.1 - 3.8e-30 104.3 0.0 9.5e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73286.1 - 8.1e-18 64.3 1.2 2e-17 63.1 1.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73286.1 - 4.4e-08 33.3 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Phage_GPO PF05929.11 GBG73286.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.7 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase rve PF00665.26 GBG73287.1 - 1.8e-14 54.0 0.0 3.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG73287.1 - 9.6e-13 48.3 0.0 2.4e-11 43.8 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73287.1 - 1.4e-10 41.1 0.0 3.3e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG73287.1 - 0.005 17.4 0.0 0.024 15.2 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73287.1 - 0.0075 16.9 0.0 0.021 15.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG73287.1 - 0.037 14.3 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG73288.1 - 5.3e-32 109.8 0.0 1e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73288.1 - 2.4e-28 98.5 0.1 5.1e-28 97.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73288.1 - 2.4e-20 72.4 0.1 4.9e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73288.1 - 2.1e-15 57.0 0.0 5.1e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG73288.1 - 0.00022 21.3 0.0 0.00062 19.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Clr5 PF14420.6 GBG73288.1 - 0.065 13.5 0.2 9.5 6.5 0.2 3.2 2 0 0 2 2 2 0 Clr5 domain DegQ PF08181.11 GBG73289.1 - 0.3 11.2 2.0 0.51 10.5 2.0 1.3 1 0 0 1 1 1 0 DegQ (SacQ) family Sporozoite_P67 PF05642.11 GBG73289.1 - 6.8 4.6 10.1 0.13 10.3 2.2 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RT_RNaseH_2 PF17919.1 GBG73291.1 - 3e-33 113.9 0.0 7.3e-33 112.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73291.1 - 2.6e-30 104.8 0.1 6.1e-30 103.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73291.1 - 3.1e-19 68.8 0.2 6.8e-19 67.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG73291.1 - 5.4e-19 68.6 0.0 1.6e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG73291.1 - 1.4e-07 31.7 2.4 0.0078 16.5 0.0 3.7 3 0 0 3 3 3 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG73291.1 - 0.0029 17.8 0.0 0.0081 16.4 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger NIR_SIR PF01077.22 GBG73291.1 - 0.015 14.8 0.2 1.4 8.5 0.2 2.5 2 0 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain RAP1 PF07218.11 GBG73291.1 - 0.44 8.8 3.7 0.81 7.9 3.7 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Retrotrans_gag PF03732.17 GBG73292.1 - 0.0029 17.8 0.4 0.042 14.1 0.1 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein Toprim_N PF08275.11 GBG73293.1 - 7.6e-05 22.8 7.5 44 4.1 0.0 8.2 2 2 6 8 8 8 0 DNA primase catalytic core, N-terminal domain Speriolin_N PF15058.6 GBG73293.1 - 0.00027 21.1 1.2 0.00044 20.4 1.2 1.2 1 0 0 1 1 1 1 Speriolin N terminus PapC_C PF13953.6 GBG73293.1 - 0.00067 19.4 22.7 4.1 7.3 0.2 7.3 2 2 2 6 6 6 5 PapC C-terminal domain RTA1 PF04479.13 GBG73293.1 - 0.019 14.6 8.6 63 3.1 0.0 6.8 5 2 3 8 8 8 0 RTA1 like protein Retrotrans_gag PF03732.17 GBG73293.1 - 0.07 13.4 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Methyltransf_1N PF02870.15 GBG73293.1 - 0.52 11.2 4.9 73 4.3 0.0 4.9 3 1 2 5 5 5 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DdrB PF12747.7 GBG73293.1 - 5 6.9 19.8 4.2 7.2 0.3 5.8 3 1 3 6 6 6 0 DdrB-like protein RVT_1 PF00078.27 GBG73294.1 - 2.6e-30 105.6 0.1 3.9e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG73294.1 - 1.1e-05 25.8 0.0 2.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73294.1 - 0.00018 22.1 0.0 0.00043 20.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG73294.1 - 0.0025 17.7 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Topo_Zn_Ribbon PF08272.11 GBG73294.1 - 0.079 12.6 0.1 0.46 10.2 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG73294.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG73295.1 - 0.31 11.3 1.6 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein RVP_2 PF08284.11 GBG73297.1 - 4.5e-07 29.7 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73297.1 - 9.6e-06 26.2 0.0 2.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73297.1 - 0.00027 21.4 0.0 0.0011 19.5 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG73297.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG73297.1 - 0.0062 16.3 0.0 0.048 13.5 0.0 2.3 2 1 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG73298.1 - 2.3e-06 28.1 0.0 8.1e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73298.1 - 7e-06 26.5 0.0 4.4e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG73298.1 - 0.00017 21.4 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73298.1 - 0.0016 18.2 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Senescence_reg PF04520.13 GBG73298.1 - 0.095 13.5 1.5 0.23 12.3 1.5 1.8 1 0 0 1 1 1 0 Senescence regulator Chromo PF00385.24 GBG73299.1 - 0.0015 18.4 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CENP-Q PF13094.6 GBG73300.1 - 0.0046 17.2 7.8 0.0046 17.2 7.8 2.4 2 2 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Filament PF00038.21 GBG73300.1 - 0.064 12.8 12.5 0.18 11.3 0.3 3.1 3 0 0 3 3 3 0 Intermediate filament protein Integrase_H2C2 PF17921.1 GBG73301.1 - 9.2e-09 35.3 0.1 2.3e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG73302.1 - 0.03 14.4 1.9 0.058 13.5 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG73302.1 - 0.093 12.4 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like LRR_8 PF13855.6 GBG73304.1 - 1.3e-23 82.5 38.8 5e-09 35.8 4.2 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 GBG73304.1 - 7.9e-19 67.5 26.9 4.9e-07 30.0 0.6 4.2 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GBG73304.1 - 4e-09 36.2 1.0 9.6e-07 28.5 1.0 2.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 GBG73304.1 - 1.2e-05 25.0 13.7 3 8.1 0.8 6.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 GBG73304.1 - 0.00027 21.1 10.4 1.5 9.7 0.7 6.4 6 1 1 7 7 7 1 Leucine Rich Repeat FNIP PF05725.12 GBG73304.1 - 0.0014 18.7 0.0 0.0043 17.2 0.0 1.9 1 0 0 1 1 1 1 FNIP Repeat NAP PF00956.18 GBG73305.1 - 1.6e-33 116.1 0.0 4.3e-33 114.7 0.0 1.6 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF1041 PF06292.17 GBG73306.1 - 0.57 10.6 6.6 0.17 12.3 2.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) Prominin PF05478.11 GBG73306.1 - 3 5.7 5.2 2.7 5.8 4.3 1.5 1 1 1 2 2 2 0 Prominin Dimer_Tnp_hAT PF05699.14 GBG73308.1 - 3.1e-06 26.9 0.0 5.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG73310.1 - 2.9e-31 108.4 0.0 1.1e-30 106.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73310.1 - 4.9e-06 26.2 0.7 9.8e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RT_RNaseH PF17917.1 GBG73311.1 - 1.9e-29 102.0 0.0 5.9e-29 100.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73311.1 - 3.4e-29 100.8 0.0 1.1e-28 99.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73311.1 - 8.6e-13 48.3 0.0 1.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG73311.1 - 7.2e-06 25.8 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73311.1 - 2.3e-05 25.0 0.0 5.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73311.1 - 0.0011 19.5 0.0 0.0039 17.7 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG73311.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF4392 PF14336.6 GBG73311.1 - 0.0022 17.5 1.0 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4392) DUF4407 PF14362.6 GBG73311.1 - 0.16 11.3 8.7 23 4.2 10.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DDHD PF02862.17 GBG73311.1 - 1 9.5 4.8 1.8 8.7 4.8 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 GBG73311.1 - 6.9 5.3 9.8 9.9 4.8 9.8 1.2 1 0 0 1 1 1 0 Presenilin Histone PF00125.24 GBG73313.1 - 4.6e-14 52.9 0.2 4.6e-14 52.9 0.2 3.1 3 2 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG73313.1 - 0.063 13.7 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 CENP-S protein NIF PF03031.18 GBG73314.1 - 5.2e-13 49.0 0.5 3.1e-09 36.8 0.1 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase dsrm PF00035.26 GBG73314.1 - 6.3e-06 26.8 0.0 2.4e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif LRRFIP PF09738.9 GBG73314.1 - 1.6 8.2 8.9 4.1 6.8 8.9 1.6 1 0 0 1 1 1 0 LRRFIP family DUF775 PF05603.12 GBG73314.1 - 8.7 5.8 6.8 29 4.1 6.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF775) zf-RVT PF13966.6 GBG73315.1 - 9.1e-07 29.5 2.2 2.5e-06 28.1 2.2 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 GBG73315.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase ATC_hydrolase PF14196.6 GBG73316.1 - 0.31 11.8 5.8 1.1 10.1 0.7 2.8 3 0 0 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Gifsy-2 PF13856.6 GBG73316.1 - 0.89 10.0 5.5 5.9 7.3 0.7 2.4 2 0 0 2 2 2 0 ATP-binding sugar transporter from pro-phage BUD22 PF09073.10 GBG73317.1 - 0.005 16.3 31.8 0.0079 15.6 31.8 1.3 1 0 0 1 1 1 1 BUD22 SLC12 PF03522.15 GBG73317.1 - 2.2 7.2 8.7 2.8 6.9 8.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 AP3D1 PF06375.11 GBG73317.1 - 6 7.1 43.7 0.54 10.5 3.1 3.1 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 SAPS PF04499.15 GBG73317.1 - 6.9 5.3 13.5 8.6 5.0 13.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 GBG73317.1 - 8.8 5.0 10.5 12 4.6 10.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain RT_RNaseH_2 PF17919.1 GBG73318.1 - 1.3e-96 317.1 0.1 2.4e-30 104.5 0.1 5.1 5 0 0 5 5 5 4 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73318.1 - 3.3e-71 239.3 0.1 7.4e-29 100.8 0.1 4.8 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73318.1 - 2.2e-69 230.4 0.2 2.9e-19 69.3 0.0 5.0 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase TolA_bind_tri PF16331.5 GBG73318.1 - 0.00029 20.8 24.8 0.16 12.1 4.1 5.4 4 0 0 4 4 4 2 TolA binding protein trimerisation Retrotrans_gag PF03732.17 GBG73318.1 - 0.0021 18.3 19.0 0.01 16.1 0.1 6.4 7 0 0 7 7 7 1 Retrotransposon gag protein DUF4806 PF16064.5 GBG73318.1 - 0.032 14.5 0.6 18 5.7 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) Spc29 PF17082.5 GBG73318.1 - 0.04 13.8 26.2 0.15 11.9 0.1 4.9 4 1 0 4 4 4 0 Spindle Pole Component 29 Integrin_b_cyt PF08725.11 GBG73318.1 - 0.098 12.4 0.0 32 4.3 0.0 3.0 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain RVT_1 PF00078.27 GBG73319.1 - 7.7e-35 120.4 0.0 1.4e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73319.1 - 2.1e-29 101.5 0.0 5.6e-29 100.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73319.1 - 6.3e-29 100.4 0.0 1.5e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73319.1 - 7.4e-13 48.4 0.2 2e-12 47.0 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG73319.1 - 1.1e-07 32.4 0.1 5.5e-06 26.9 0.0 3.2 3 0 0 3 3 3 1 Aspartyl protease rve PF00665.26 GBG73319.1 - 1.6e-07 31.5 0.0 5.2e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG73319.1 - 8.4e-07 28.8 0.0 1e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73319.1 - 7.3e-05 23.3 0.1 0.00052 20.5 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease SlyX PF04102.12 GBG73319.1 - 0.0041 17.7 1.4 0.0041 17.7 1.4 4.9 6 0 0 6 6 5 1 SlyX Retrotrans_gag PF03732.17 GBG73319.1 - 0.0041 17.3 0.1 0.22 11.8 0.0 3.1 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG73319.1 - 0.034 13.9 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF4392 PF14336.6 GBG73319.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Phage_GPO PF05929.11 GBG73319.1 - 5.4 6.6 13.9 0.47 10.0 0.0 3.0 2 1 2 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG73320.1 - 4e-31 108.3 0.9 5.8e-31 107.7 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73320.1 - 7.3e-25 86.9 0.0 2.2e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73320.1 - 5.2e-16 58.8 0.0 2.2e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG73320.1 - 0.00075 19.4 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain APG17 PF04108.12 GBG73320.1 - 0.0089 15.2 0.4 4.1 6.4 0.0 2.6 2 1 0 2 2 2 2 Autophagy protein Apg17 RVT_1 PF00078.27 GBG73321.1 - 3.3e-29 102.0 0.1 5.7e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73321.1 - 2.1e-26 91.9 0.0 5.7e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73321.1 - 1.5e-25 89.5 0.0 3.2e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73321.1 - 4.1e-15 55.6 1.4 9.9e-15 54.4 1.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73321.1 - 1.1e-08 35.3 0.0 3.4e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG73321.1 - 3.2e-06 27.7 0.0 6.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73321.1 - 3.6e-05 24.2 0.0 7.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG73321.1 - 8e-05 22.4 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG73321.1 - 0.00081 19.6 0.0 0.004 17.4 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG73321.1 - 0.0085 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Lys-AminoMut_A PF09043.11 GBG73321.1 - 0.25 9.8 0.4 0.37 9.2 0.4 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit RVT_1 PF00078.27 GBG73322.1 - 5.1e-26 91.6 0.0 8.2e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG73322.1 - 3e-06 27.0 0.0 6.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73322.1 - 0.052 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG73322.1 - 0.12 13.0 0.0 0.3 11.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease GPS2_interact PF15784.5 GBG73322.1 - 0.21 12.1 1.9 6.2 7.3 1.6 2.5 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF812 PF05667.11 GBG73322.1 - 2.1 7.1 8.1 2.7 6.7 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) HrpB7 PF09486.10 GBG73322.1 - 2.2 8.6 10.1 0.18 12.2 4.3 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Uds1 PF15456.6 GBG73322.1 - 2.4 8.3 7.9 56 3.9 5.9 3.3 2 1 0 2 2 2 0 Up-regulated During Septation zf-CCHC_4 PF14392.6 GBG73323.1 - 0.016 14.9 0.1 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG73323.1 - 0.083 13.0 4.1 0.13 12.4 4.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG73323.1 - 0.15 11.9 2.9 0.11 12.3 1.0 1.8 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG73324.1 - 1.8e-56 191.2 0.3 4.9e-26 91.6 0.0 3.2 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73324.1 - 3e-40 136.3 0.0 5.3e-25 87.4 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73324.1 - 6e-26 90.8 0.0 2e-18 66.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG73324.1 - 0.00017 21.4 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73324.1 - 0.00017 22.1 0.0 0.00038 21.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73324.1 - 0.00027 21.4 0.0 0.00059 20.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG73324.1 - 0.03 14.2 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Rz1 PF06085.11 GBG73324.1 - 0.1 12.4 0.6 0.31 10.8 0.6 1.8 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor Sporozoite_P67 PF05642.11 GBG73325.1 - 6.7 4.7 12.0 0.015 13.4 2.0 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RVT_1 PF00078.27 GBG73326.1 - 4.4e-58 196.4 1.3 1.1e-28 100.2 0.2 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73326.1 - 3.2e-25 88.1 0.2 1.3e-22 79.7 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73326.1 - 2.6e-13 50.2 0.0 5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-RING_2 PF13639.6 GBG73327.1 - 2.1e-14 53.6 7.7 2.5e-14 53.3 7.7 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG73327.1 - 3.7e-11 42.7 7.9 4.5e-11 42.4 7.9 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG73327.1 - 2.4e-09 36.9 7.0 3.1e-09 36.5 7.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG73327.1 - 2.9e-09 36.5 6.8 2.9e-09 36.5 6.8 1.5 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 GBG73327.1 - 4.7e-09 36.4 10.1 1.1e-08 35.2 10.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GBG73327.1 - 7.5e-07 29.1 4.9 1.1e-06 28.6 4.9 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GBG73327.1 - 3.6e-06 26.7 5.4 4.6e-06 26.4 5.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG73327.1 - 2.1e-05 24.4 5.4 2.8e-05 24.0 5.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GBG73327.1 - 0.00026 21.0 6.5 0.00071 19.6 6.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GBG73327.1 - 0.0011 18.7 5.6 0.0021 17.9 5.7 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GBG73327.1 - 0.014 15.5 3.7 0.016 15.3 3.7 1.1 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 GBG73327.1 - 0.023 14.5 1.6 0.028 14.2 1.6 1.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 GBG73327.1 - 0.044 13.4 8.0 0.097 12.3 8.0 1.6 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GBG73327.1 - 0.27 11.4 9.0 1.1 9.4 9.0 1.9 1 1 0 1 1 1 0 RING-variant domain GAGA PF09237.11 GBG73327.1 - 0.29 11.0 2.2 4 7.3 0.1 2.1 2 0 0 2 2 2 0 GAGA factor FANCL_C PF11793.8 GBG73327.1 - 0.34 11.1 12.8 14 6.0 12.8 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain Integrase_H2C2 PF17921.1 GBG73328.1 - 1.3e-10 41.2 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG73328.1 - 0.00062 19.5 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1564) NHase_beta PF02211.15 GBG73328.1 - 0.0025 17.9 0.2 3.1 7.8 0.0 2.7 3 0 0 3 3 3 2 Nitrile hydratase beta subunit TOBE_2 PF08402.10 GBG73328.1 - 0.0035 17.5 0.3 4 7.7 0.0 2.4 2 0 0 2 2 2 2 TOBE domain Mistic PF11458.8 GBG73328.1 - 0.032 14.2 0.2 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Membrane-integrating protein Mistic MLVIN_C PF18697.1 GBG73328.1 - 0.033 14.3 0.1 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain VirDNA-topo-I_N PF09266.10 GBG73328.1 - 0.14 12.3 0.7 2.4 8.4 0.0 3.1 3 0 0 3 3 3 0 Viral DNA topoisomerase I, N-terminal EMP24_GP25L PF01105.24 GBG73328.1 - 0.16 11.9 0.2 12 5.8 0.0 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD SOAR PF16533.5 GBG73328.1 - 0.3 11.1 4.0 4.2 7.4 0.2 2.6 2 0 0 2 2 2 0 STIM1 Orai1-activating region DUF1918 PF08940.11 GBG73328.1 - 0.46 10.2 2.4 89 2.8 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1918) ERM PF00769.19 GBG73328.1 - 2.3 8.0 13.7 4.7 6.9 2.7 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family UVR PF02151.19 GBG73328.1 - 3.4 7.5 7.4 18 5.2 0.5 2.7 2 0 0 2 2 2 0 UvrB/uvrC motif GAGBD PF16828.5 GBG73328.1 - 3.6 7.7 6.0 16 5.6 0.2 2.6 3 0 0 3 3 3 0 GAG-binding domain on surface antigen DUF4398 PF14346.6 GBG73328.1 - 4.6 7.9 8.1 22 5.8 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) RVT_1 PF00078.27 GBG73329.1 - 8.8e-05 22.1 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG73330.1 - 2.4e-14 53.4 0.0 3.6e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG73333.1 - 3.7e-14 52.6 0.0 9.2e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73333.1 - 6.1e-14 52.2 0.0 2.1e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG73333.1 - 4e-08 33.7 0.0 8.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG73333.1 - 4.3e-08 32.9 0.0 7.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG73333.1 - 1e-06 29.3 0.0 2.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG73333.1 - 0.0084 15.9 0.4 0.018 14.9 0.4 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG73333.1 - 0.058 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG73333.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger TB2_DP1_HVA22 PF03134.19 GBG73335.1 - 7.1e-21 73.9 4.7 7.8e-21 73.8 4.7 1.0 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RT_RNaseH_2 PF17919.1 GBG73336.1 - 4.5e-31 106.8 0.1 9.9e-31 105.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73336.1 - 1.4e-29 103.2 0.0 2.4e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73336.1 - 2.8e-19 69.3 0.0 6.8e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ELFV_dehydrog PF00208.21 GBG73336.1 - 0.025 14.3 0.7 0.036 13.8 0.7 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Mito_fiss_reg PF05308.11 GBG73336.1 - 0.025 14.7 2.3 0.03 14.4 1.0 1.7 1 1 0 1 1 1 0 Mitochondrial fission regulator K_channel_TID PF07941.11 GBG73336.1 - 1.6 9.3 9.8 3.7 8.1 9.8 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DNA_pack_N PF02500.15 GBG73337.1 - 0.004 17.0 0.0 0.0046 16.8 0.0 1.1 1 0 0 1 1 1 1 Probable DNA packing protein, N-terminus DUF1664 PF07889.12 GBG73337.1 - 0.0086 16.1 3.6 0.0086 16.1 3.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF3527 PF12043.8 GBG73337.1 - 0.068 12.7 1.0 0.082 12.5 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) DUF659 PF04937.15 GBG73339.1 - 6.2e-41 139.8 0.0 9.6e-41 139.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG73340.1 - 1.5e-29 102.0 0.0 8.2e-29 99.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73340.1 - 2.2e-27 95.4 0.1 6.3e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73340.1 - 0.0038 16.8 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73340.1 - 0.036 14.2 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 Integrase zinc binding domain Phage_GPO PF05929.11 GBG73340.1 - 0.35 10.4 8.1 0.36 10.4 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PSK PF06404.12 GBG73340.1 - 6.8 7.8 7.3 27 5.8 7.3 2.0 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) rve PF00665.26 GBG73341.1 - 1.7e-08 34.7 0.0 4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Dppa2_A PF14049.6 GBG73341.1 - 0.00062 19.8 8.3 0.015 15.4 3.8 2.4 2 0 0 2 2 2 2 Dppa2/4 conserved region in higher vertebrates Miga PF10265.9 GBG73341.1 - 0.2 10.6 4.0 0.3 10.0 4.0 1.2 1 0 0 1 1 1 0 Mitoguardin RT_RNaseH_2 PF17919.1 GBG73343.1 - 2.6e-32 110.8 0.0 6.2e-32 109.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73343.1 - 8.4e-30 103.2 0.1 2e-29 101.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73343.1 - 5.8e-18 64.7 0.2 1.4e-17 63.6 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG73343.1 - 8.6e-17 61.4 0.8 1e-11 44.8 0.2 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG73343.1 - 0.00096 19.3 0.0 0.004 17.3 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG73343.1 - 0.045 14.0 0.1 0.5 10.7 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein rve PF00665.26 GBG73343.1 - 0.092 12.9 1.9 0.19 11.9 0.0 2.5 3 0 0 3 3 3 0 Integrase core domain RVP_2 PF08284.11 GBG73343.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4404 PF14357.6 GBG73343.1 - 2.6 8.8 4.8 1.6 9.4 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Integrase_H2C2 PF17921.1 GBG73344.1 - 3.1e-07 30.4 0.0 8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG73345.1 - 4.3e-14 52.6 0.1 3.9e-12 46.2 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3619 PF12279.8 GBG73345.1 - 0.0099 16.2 0.4 0.03 14.6 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3619) rve PF00665.26 GBG73345.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG73346.1 - 2.9e-30 105.5 0.0 4.3e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73346.1 - 4.7e-30 104.0 0.0 9.5e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73346.1 - 1.3e-26 92.6 0.0 3.3e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73346.1 - 6.3e-16 58.2 0.1 1.3e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73346.1 - 0.00011 22.3 0.1 0.00032 20.9 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG73347.1 - 0.0034 17.3 1.4 0.0078 16.2 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG73347.1 - 0.099 12.9 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein FtsK_4TM PF13491.6 GBG73347.1 - 0.34 10.6 0.0 0.34 10.6 0.0 1.5 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE FAM199X PF15814.5 GBG73347.1 - 0.39 9.7 8.9 0.65 9.0 8.9 1.3 1 0 0 1 1 1 0 Protein family FAM199X zf-CCHC_3 PF13917.6 GBG73348.1 - 0.003 17.5 1.4 0.0068 16.3 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG73348.1 - 0.082 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein FtsK_4TM PF13491.6 GBG73348.1 - 0.29 10.8 1.4 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE FAM199X PF15814.5 GBG73348.1 - 0.33 10.0 9.0 0.55 9.2 9.0 1.3 1 0 0 1 1 1 0 Protein family FAM199X Dppa2_A PF14049.6 GBG73348.1 - 3.5 7.8 9.3 14 5.9 2.2 2.5 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates N-SET PF11764.8 GBG73350.1 - 0.027 14.6 0.4 0.068 13.3 0.2 1.6 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N DUF533 PF04391.12 GBG73350.1 - 0.054 13.1 0.7 5 6.6 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF533) DUF533 PF04391.12 GBG73351.1 - 0.06 12.9 0.6 5.2 6.6 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF533) N-SET PF11764.8 GBG73351.1 - 0.072 13.2 1.2 0.079 13.1 0.3 1.4 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N zf-CCHC PF00098.23 GBG73352.1 - 3.4e-08 33.2 2.3 6.2e-08 32.4 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG73352.1 - 0.00029 20.6 1.1 0.00055 19.7 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG73352.1 - 0.0015 18.4 1.9 0.0049 16.7 1.9 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG73352.1 - 0.092 12.7 2.0 0.19 11.8 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle CDC27 PF09507.10 GBG73352.1 - 0.23 10.8 22.2 0.36 10.2 22.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-CCHC_4 PF14392.6 GBG73352.1 - 0.28 11.0 0.8 0.53 10.1 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG73353.1 - 3.1e-12 46.4 0.1 6e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG73353.1 - 3e-07 30.9 0.0 8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73353.1 - 7.5e-05 23.3 0.1 0.00023 21.7 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG73353.1 - 0.019 14.7 0.3 0.058 13.2 0.0 2.0 2 1 0 2 2 2 0 Aspartyl protease RVP PF00077.20 GBG73353.1 - 0.17 12.2 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease ICA69 PF04629.14 GBG73353.1 - 0.24 11.7 6.2 0.41 10.9 6.2 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain CDC45 PF02724.14 GBG73353.1 - 4.9 5.3 7.3 7.3 4.7 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Chromo PF00385.24 GBG73355.1 - 1.6e-12 47.1 0.0 2.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FmiP_Thoc5 PF09766.9 GBG73355.1 - 0.33 10.2 0.4 0.48 9.6 0.0 1.4 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 RVT_1 PF00078.27 GBG73356.1 - 9.7e-30 103.7 0.0 1.3e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG73358.1 - 9e-21 74.4 0.2 2.7e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG73358.1 - 0.0083 16.4 10.9 0.01 16.1 0.0 4.1 3 1 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG73358.1 - 0.022 14.7 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF421 PF04239.12 GBG73358.1 - 0.2 11.4 0.3 0.47 10.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Rotamase_2 PF13145.6 GBG73358.1 - 0.56 11.0 4.9 4.5 8.1 6.0 2.0 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF2408 PF10303.9 GBG73358.1 - 2.6 8.6 7.6 9.2 6.8 7.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 GBG73358.1 - 5.1 7.6 12.3 0.99 9.9 3.8 3.1 3 0 0 3 3 3 0 Snapin/Pallidin BLOC1_2 PF10046.9 GBG73358.1 - 6.7 7.1 7.6 0.9 9.9 2.2 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RT_RNaseH_2 PF17919.1 GBG73359.1 - 1.8e-23 82.4 0.0 3.6e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73359.1 - 4.6e-21 75.1 0.0 4.3e-20 72.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73359.1 - 1.2e-07 32.0 0.0 3.4e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG73359.1 - 0.1 12.4 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG73360.1 - 1.9e-24 86.5 0.0 3e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG73360.1 - 0.011 15.6 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Lys-AminoMut_A PF09043.11 GBG73360.1 - 0.38 9.2 0.9 0.56 8.6 0.9 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit RVT_1 PF00078.27 GBG73361.1 - 1.1e-55 188.5 0.0 2.9e-27 95.6 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73361.1 - 8.4e-25 86.7 0.0 2.2e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73361.1 - 2.4e-22 79.2 0.0 6.1e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73361.1 - 5.7e-17 61.6 0.2 1.4e-16 60.4 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73361.1 - 9.4e-10 38.7 0.0 2.5e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain WD40 PF00400.32 GBG73361.1 - 4.9e-06 27.2 1.7 2e-05 25.3 1.7 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG73361.1 - 0.00017 21.8 0.0 0.00041 20.6 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Chromo PF00385.24 GBG73361.1 - 0.009 15.9 1.1 0.012 15.5 0.1 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 GBG73361.1 - 0.026 15.1 0.0 0.77 10.4 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73361.1 - 0.032 14.0 0.0 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG73361.1 - 0.038 14.6 0.0 0.88 10.3 0.0 2.8 2 0 0 2 2 2 0 Aspartyl protease RT_RNaseH PF17917.1 GBG73362.1 - 3.2e-19 69.1 0.0 5.8e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73362.1 - 1.6e-18 66.6 0.0 2.6e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73362.1 - 7.2e-18 64.9 0.0 3.3e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73362.1 - 1.6e-14 53.7 0.1 3.9e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain EF-hand_6 PF13405.6 GBG73363.1 - 2.3e-14 52.0 0.3 0.0016 18.2 0.0 3.6 4 0 0 4 4 3 3 EF-hand domain EF-hand_7 PF13499.6 GBG73363.1 - 2.4e-12 47.1 4.0 1e-09 38.7 1.4 2.6 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GBG73363.1 - 1.3e-11 43.2 0.4 0.00035 19.9 1.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GBG73363.1 - 1.2e-07 31.5 0.5 5.1e-06 26.3 0.3 2.9 2 1 1 3 3 3 2 EF-hand domain pair BUD22 PF09073.10 GBG73363.1 - 2.8e-05 23.7 3.5 3.3e-05 23.4 3.5 1.1 1 0 0 1 1 1 1 BUD22 FYDLN_acid PF09538.10 GBG73363.1 - 0.00011 22.8 2.4 0.0002 22.0 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) Plasmodium_Vir PF05795.11 GBG73363.1 - 0.00044 19.8 0.8 0.00057 19.4 0.8 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein SR-25 PF10500.9 GBG73363.1 - 0.0011 18.6 6.4 0.0016 18.1 6.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RPN2_C PF18004.1 GBG73363.1 - 0.0012 18.8 11.7 0.0017 18.3 11.7 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 GBG73363.1 - 0.0014 18.3 7.3 0.0023 17.6 7.3 1.3 1 0 0 1 1 1 1 FAM176 family Eapp_C PF10238.9 GBG73363.1 - 0.0016 18.5 1.1 0.0022 18.1 1.1 1.3 1 0 0 1 1 1 1 E2F-associated phosphoprotein DUF5523 PF17661.1 GBG73363.1 - 0.0016 18.2 9.3 0.0022 17.7 9.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5523) DUF2052 PF09747.9 GBG73363.1 - 0.0022 18.2 7.2 0.003 17.7 7.2 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Radial_spoke PF04712.12 GBG73363.1 - 0.0023 17.0 6.6 0.0029 16.6 6.6 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein RPA43_OB PF17875.1 GBG73363.1 - 0.0035 17.9 2.6 0.0053 17.4 2.6 1.2 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I SpoIIP PF07454.11 GBG73363.1 - 0.0038 16.7 1.7 0.0046 16.4 1.7 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) BSP_II PF05432.11 GBG73363.1 - 0.0046 16.7 14.0 0.0063 16.3 14.0 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF1754 PF08555.10 GBG73363.1 - 0.0051 17.6 17.3 0.0092 16.8 17.3 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Sin_N PF04801.13 GBG73363.1 - 0.0056 15.9 0.4 0.0073 15.6 0.4 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region Pox_Ag35 PF03286.14 GBG73363.1 - 0.0087 15.9 13.2 0.013 15.3 13.2 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein V_ATPase_I PF01496.19 GBG73363.1 - 0.0093 13.9 2.8 0.012 13.6 2.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family AIF_C PF14721.6 GBG73363.1 - 0.014 15.7 1.4 0.022 15.1 1.4 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TFB6 PF17110.5 GBG73363.1 - 0.014 15.1 1.9 0.021 14.6 1.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TRAP_alpha PF03896.16 GBG73363.1 - 0.016 14.5 1.0 0.021 14.0 1.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit EF-hand_11 PF08976.11 GBG73363.1 - 0.018 15.9 0.1 0.025 15.4 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 GBG73363.1 - 0.025 14.1 2.3 0.15 11.6 1.2 2.6 2 0 0 2 2 2 0 EF hand DNA_pol_phi PF04931.13 GBG73363.1 - 0.029 12.5 11.8 0.039 12.1 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4820 PF16091.5 GBG73363.1 - 0.043 13.2 5.5 0.063 12.6 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Connexin PF00029.19 GBG73363.1 - 0.043 13.6 5.2 0.06 13.1 5.2 1.1 1 0 0 1 1 1 0 Connexin DUF3043 PF11241.8 GBG73363.1 - 0.043 13.8 1.5 0.068 13.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Nucleo_P87 PF07267.11 GBG73363.1 - 0.051 12.4 1.8 0.063 12.1 1.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3506 PF12014.8 GBG73363.1 - 0.053 13.5 0.6 0.093 12.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) DUF3464 PF11947.8 GBG73363.1 - 0.053 13.3 6.7 0.083 12.6 6.7 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 NEMP PF10225.9 GBG73363.1 - 0.056 13.1 1.0 0.083 12.5 1.0 1.2 1 0 0 1 1 1 0 NEMP family PPL5 PF18168.1 GBG73363.1 - 0.062 12.6 2.9 0.087 12.1 2.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DDHD PF02862.17 GBG73363.1 - 0.066 13.4 0.1 0.068 13.3 0.1 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 GBG73363.1 - 0.066 12.0 1.2 0.074 11.8 1.2 1.1 1 0 0 1 1 1 0 Presenilin DUF1387 PF07139.11 GBG73363.1 - 0.067 12.9 11.5 0.092 12.5 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Tim54 PF11711.8 GBG73363.1 - 0.069 11.9 7.6 0.11 11.3 7.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EF-hand_4 PF12763.7 GBG73363.1 - 0.091 12.7 0.3 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DNApol_Exo PF18136.1 GBG73363.1 - 0.098 11.8 3.7 0.17 11.0 3.7 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain OATP PF03137.20 GBG73363.1 - 0.1 10.8 0.6 0.14 10.5 0.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RNA_pol_Rpc4 PF05132.14 GBG73363.1 - 0.15 12.5 5.8 0.23 11.9 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 eIF3_subunit PF08597.10 GBG73363.1 - 0.15 11.9 19.4 0.23 11.3 19.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Folate_carrier PF01770.18 GBG73363.1 - 0.16 10.7 0.8 0.19 10.4 0.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier NPR3 PF03666.13 GBG73363.1 - 0.18 10.6 4.9 0.23 10.2 4.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CENP-B_dimeris PF09026.10 GBG73363.1 - 0.18 12.2 4.8 0.44 11.0 4.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 GBG73363.1 - 0.19 11.7 8.8 0.3 11.1 8.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Afi1 PF07792.12 GBG73363.1 - 0.21 12.1 5.7 0.33 11.4 5.7 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.22 GBG73363.1 - 0.22 10.7 2.2 0.29 10.3 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 GBG73363.1 - 0.24 10.8 12.0 0.33 10.3 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FTO_NTD PF12933.7 GBG73363.1 - 0.25 10.5 2.0 0.37 10.0 2.0 1.2 1 0 0 1 1 1 0 FTO catalytic domain CobT PF06213.12 GBG73363.1 - 0.29 10.5 12.0 0.51 9.7 12.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4337 PF14235.6 GBG73363.1 - 0.31 11.2 1.6 0.41 10.7 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RAI16-like PF10257.9 GBG73363.1 - 0.33 9.8 1.2 0.41 9.5 1.2 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein dsRBD2 PF17842.1 GBG73363.1 - 0.38 10.9 4.8 0.61 10.3 4.8 1.2 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 DUF913 PF06025.12 GBG73363.1 - 0.39 9.6 3.3 0.53 9.2 3.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NARP1 PF12569.8 GBG73363.1 - 0.41 9.5 13.7 0.58 9.0 13.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TMEM51 PF15345.6 GBG73363.1 - 0.43 10.4 7.6 0.68 9.7 7.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 EIIBC-GUT_N PF03612.14 GBG73363.1 - 0.56 9.9 4.2 0.86 9.3 4.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Cellulose_synt PF03552.14 GBG73363.1 - 0.58 8.6 3.5 0.74 8.2 3.5 1.1 1 0 0 1 1 1 0 Cellulose synthase MCM_bind PF09739.9 GBG73363.1 - 0.58 8.5 4.6 0.88 7.9 4.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDC27 PF09507.10 GBG73363.1 - 0.7 9.2 15.6 0.94 8.8 15.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CENP-N PF05238.13 GBG73363.1 - 0.73 9.1 4.0 0.96 8.7 4.0 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like RAB3GAP2_C PF14656.6 GBG73363.1 - 0.78 7.9 6.4 1.1 7.4 6.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Myc_N PF01056.18 GBG73363.1 - 0.91 9.4 8.7 1.4 8.7 8.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region OAD_gamma PF04277.13 GBG73363.1 - 0.93 10.1 5.9 2.1 9.0 5.9 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Vfa1 PF08432.10 GBG73363.1 - 1.1 9.5 15.1 1.7 9.0 15.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4775 PF16001.5 GBG73363.1 - 1.7 8.0 18.0 2.3 7.5 18.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) DUF2828 PF11443.8 GBG73363.1 - 1.8 6.6 7.1 2.5 6.1 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) eIF_4EBP PF05456.11 GBG73363.1 - 1.8 8.6 4.3 3 7.8 4.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CDC45 PF02724.14 GBG73363.1 - 1.8 6.7 10.0 2.5 6.3 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoside_tran PF01733.18 GBG73363.1 - 2.1 7.6 3.2 3 7.1 3.2 1.2 1 0 0 1 1 1 0 Nucleoside transporter MAS20 PF02064.15 GBG73363.1 - 2.6 8.1 11.4 4.6 7.4 11.4 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor Peptidase_S49_N PF08496.10 GBG73363.1 - 2.7 8.0 8.9 5.1 7.1 8.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ureide_permease PF07168.11 GBG73363.1 - 3.1 6.5 3.7 4.4 6.0 3.7 1.1 1 0 0 1 1 1 0 Ureide permease RR_TM4-6 PF06459.12 GBG73363.1 - 3.1 7.5 14.5 4.5 7.0 14.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_3_Rpc31 PF11705.8 GBG73363.1 - 3.7 7.7 18.9 5.6 7.2 18.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 HSP90 PF00183.18 GBG73363.1 - 4.1 6.2 14.3 5.6 5.7 14.3 1.1 1 0 0 1 1 1 0 Hsp90 protein PSK PF06404.12 GBG73363.1 - 6.1 7.9 12.8 10 7.2 12.8 1.3 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) Atrophin-1 PF03154.15 GBG73363.1 - 6.5 4.9 11.8 8.7 4.5 11.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family FancD2 PF14631.6 GBG73363.1 - 6.7 4.0 7.8 9.2 3.5 7.8 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DDRGK PF09756.9 GBG73363.1 - 7.4 6.1 26.0 11 5.6 26.0 1.1 1 0 0 1 1 1 0 DDRGK domain DUF4246 PF14033.6 GBG73364.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) CDC45 PF02724.14 GBG73364.1 - 0.31 9.3 9.8 0.4 8.9 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG73364.1 - 0.96 8.1 2.2 1.3 7.7 2.2 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG73364.1 - 1.6 6.8 15.8 2.6 6.2 15.8 1.3 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.23 GBG73365.1 - 7.9e-06 25.7 3.2 1.4e-05 24.9 3.2 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG73365.1 - 2.1e-05 24.3 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73365.1 - 0.016 15.8 0.0 0.045 14.3 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG73365.1 - 0.017 15.0 4.1 0.028 14.2 4.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 GBG73365.1 - 0.067 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF1726 PF08351.11 GBG73365.1 - 0.084 12.8 0.2 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) Integrase_H2C2 PF17921.1 GBG73367.1 - 2.9e-14 52.9 0.0 1e-13 51.1 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73367.1 - 3.6e-14 53.0 0.0 7.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG73367.1 - 0.0013 19.0 0.2 0.0035 17.6 0.2 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG73367.1 - 0.014 15.2 0.2 0.014 15.2 0.2 1.9 2 0 0 2 2 2 0 Zinc knuckle rve_3 PF13683.6 GBG73367.1 - 0.022 14.5 0.0 0.084 12.7 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 GBG73367.1 - 0.086 13.1 0.2 0.23 11.7 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG73367.1 - 2.3 8.5 4.2 0.57 10.3 0.5 2.0 2 0 0 2 2 2 0 Zinc knuckle Rpr2 PF04032.16 GBG73369.1 - 5e-12 45.9 9.5 7e-11 42.3 0.4 3.0 2 0 0 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain gag-asp_proteas PF13975.6 GBG73371.1 - 4e-06 27.3 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73371.1 - 4.3e-06 27.3 0.0 9.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG73371.1 - 0.0027 17.5 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73371.1 - 0.0087 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease cNMP_binding PF00027.29 GBG73371.1 - 0.051 13.6 0.4 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Cyclic nucleotide-binding domain UPF0561 PF10573.9 GBG73371.1 - 0.2 11.8 1.0 0.39 10.8 1.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Peptidase_A3 PF02160.15 GBG73371.1 - 0.23 10.9 0.5 0.46 9.9 0.0 1.8 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) rve PF00665.26 GBG73374.1 - 9e-09 35.6 0.1 5e-08 33.2 0.1 2.1 2 0 0 2 2 2 1 Integrase core domain TetR_C_15 PF17918.1 GBG73374.1 - 0.021 15.6 0.0 0.053 14.3 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain rve_3 PF13683.6 GBG73374.1 - 0.083 12.7 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain DUF3825 PF12873.7 GBG73375.1 - 5.8e-36 124.2 0.0 4.7e-20 72.1 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3825) DUF3825 PF12873.7 GBG73376.1 - 5.2e-36 124.3 0.0 4.4e-20 72.2 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3825) DUF659 PF04937.15 GBG73377.1 - 4.2e-22 78.6 0.0 7.7e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73377.1 - 0.026 14.3 0.1 0.057 13.2 0.1 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Lactamase_B_2 PF12706.7 GBG73379.1 - 1.1e-24 87.1 0.0 4e-23 82.0 0.1 2.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GBG73379.1 - 9.1e-06 25.8 2.1 2.7e-05 24.3 2.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Bowman-Birk_leg PF00228.20 GBG73379.1 - 0.12 12.8 0.1 0.32 11.4 0.1 1.8 1 0 0 1 1 1 0 Bowman-Birk serine protease inhibitor family RVT_1 PF00078.27 GBG73380.1 - 3e-26 92.3 0.1 7.1e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73380.1 - 3.1e-09 37.1 0.1 8.7e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG73380.1 - 2.3e-06 28.2 0.0 5.3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73380.1 - 1.5e-05 25.4 0.0 3.9e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG73380.1 - 1.7e-05 25.0 3.6 0.00054 20.2 0.0 3.6 3 0 0 3 3 3 1 Retrotransposon gag protein rve PF00665.26 GBG73380.1 - 0.00026 21.1 0.0 0.0016 18.6 0.0 2.4 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG73380.1 - 0.0008 19.2 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73380.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease YPEB PF14620.6 GBG73380.1 - 0.0086 15.5 1.0 0.018 14.4 1.0 1.5 1 0 0 1 1 1 1 YpeB sporulation RT_RNaseH_2 PF17919.1 GBG73380.1 - 0.093 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73381.1 - 2.5e-24 86.1 0.0 5.2e-24 85.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG73381.1 - 2.4e-08 33.8 0.0 5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73381.1 - 4.6e-07 30.4 0.0 9.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73381.1 - 2e-06 28.3 0.0 5e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73381.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF4187 PF13821.6 GBG73381.1 - 0.017 14.9 2.7 0.23 11.2 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) RT_RNaseH PF17917.1 GBG73382.1 - 9.5e-20 70.9 1.8 3e-19 69.3 1.8 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase G-patch PF01585.23 GBG73382.1 - 4.2e-12 45.7 0.3 1.1e-11 44.5 0.3 1.7 1 0 0 1 1 1 1 G-patch domain RT_RNaseH_2 PF17919.1 GBG73382.1 - 1.3e-11 44.4 0.2 3.4e-11 43.1 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73382.1 - 1.6e-07 31.5 0.0 0.013 15.6 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain G-patch_2 PF12656.7 GBG73382.1 - 0.001 19.1 0.1 0.0034 17.4 0.1 1.9 1 0 0 1 1 1 1 G-patch domain Integrase_H2C2 PF17921.1 GBG73382.1 - 0.0028 17.7 0.6 0.0073 16.4 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG73382.1 - 0.045 13.5 0.1 0.27 11.1 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain NAAA-beta PF15508.6 GBG73382.1 - 0.073 13.4 0.0 9.9 6.6 0.0 2.9 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1664 PF07889.12 GBG73382.1 - 0.1 12.6 5.5 0.16 12.0 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5069 PF16798.5 GBG73382.1 - 0.11 12.7 0.1 3 8.0 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) ADIP PF11559.8 GBG73382.1 - 2.9 8.0 12.4 8.3 6.5 12.4 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Maf1 PF09174.10 GBG73382.1 - 5.5 7.1 5.5 33 4.6 0.1 3.2 3 0 0 3 3 3 0 Maf1 regulator RT_RNaseH PF17917.1 GBG73383.1 - 7.5e-20 71.2 0.0 2.5e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73383.1 - 8.6e-16 57.8 0.0 2.1e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG73383.1 - 4.7e-11 42.6 0.0 1.9e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG73383.1 - 0.00013 22.1 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG73383.1 - 0.00063 19.5 0.1 0.81 9.4 0.0 2.3 2 0 0 2 2 2 2 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG73383.1 - 0.026 15.1 0.0 0.16 12.7 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG73383.1 - 0.091 13.3 0.0 17 6.1 0.0 2.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG73383.1 - 0.11 12.3 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease B1 PF02246.15 GBG73385.1 - 0.03 14.3 0.2 0.067 13.2 0.1 1.6 2 0 0 2 2 2 0 Protein L b1 domain gag-asp_proteas PF13975.6 GBG73387.1 - 1.8e-06 28.4 0.0 7.7e-06 26.4 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG73387.1 - 3.4e-06 26.7 0.1 6.2e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG73387.1 - 6.5e-06 26.7 0.0 2.4e-05 24.9 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease Gsf2 PF11055.8 GBG73387.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose signalling factor 2 Asp_protease PF09668.10 GBG73387.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Rhomboid_N PF12122.8 GBG73389.1 - 0.049 13.8 0.4 0.11 12.7 0.4 1.5 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease Cellulose_synt PF03552.14 GBG73389.1 - 0.35 9.3 1.5 0.56 8.6 1.5 1.2 1 0 0 1 1 1 0 Cellulose synthase TolA_bind_tri PF16331.5 GBG73389.1 - 2.6 8.2 11.3 2.9 8.0 9.5 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation RT_RNaseH_2 PF17919.1 GBG73390.1 - 2.8e-54 181.3 0.1 1.5e-22 79.5 0.0 3.6 2 1 1 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73390.1 - 1.2e-43 149.2 5.8 7.9e-24 84.4 0.2 3.7 4 0 0 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73390.1 - 4e-41 139.6 0.1 2.6e-18 66.2 0.3 3.7 2 1 1 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73390.1 - 8.2e-28 96.3 0.1 1.1e-19 70.3 0.1 2.9 2 0 0 2 2 2 2 Integrase zinc binding domain Asp_protease PF09668.10 GBG73390.1 - 0.00022 21.0 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease Asp_protease_2 PF13650.6 GBG73390.1 - 0.00051 20.6 0.0 0.21 12.2 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73390.1 - 0.00081 19.9 0.0 0.059 13.9 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG73390.1 - 0.061 13.6 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Peptidase_U32 PF01136.19 GBG73391.1 - 0.092 11.9 0.0 3.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase family U32 Integrase_H2C2 PF17921.1 GBG73393.1 - 1.1e-18 67.1 0.3 2.9e-18 65.7 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73393.1 - 2.7e-06 27.6 0.1 1.1e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG73393.1 - 8.5e-06 26.2 0.0 2.2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73393.1 - 1.2e-05 25.9 0.0 2.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73393.1 - 2.5e-05 24.1 0.0 5.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73393.1 - 0.00063 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG73393.1 - 0.0021 18.3 0.0 0.0074 16.5 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.24 GBG73393.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG73393.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG73394.1 - 0.021 15.1 0.6 0.084 13.2 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein PRTP PF01366.18 GBG73395.1 - 2.8 5.9 8.3 3.8 5.4 8.3 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RT_RNaseH_2 PF17919.1 GBG73396.1 - 5.1e-32 109.9 0.0 1.1e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73396.1 - 6.9e-26 90.6 0.0 1.5e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73396.1 - 8e-25 87.7 0.1 1.6e-24 86.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73396.1 - 9.7e-16 57.6 0.0 2.1e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73396.1 - 8.9e-15 54.9 0.0 2.3e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG73396.1 - 2.7e-05 24.6 0.0 7.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73396.1 - 0.0058 17.2 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF3437 PF11919.8 GBG73396.1 - 0.043 13.7 0.2 9.4 6.2 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF659 PF04937.15 GBG73397.1 - 3.1e-34 118.0 0.0 5e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Es2 PF09751.9 GBG73398.1 - 0.049 13.4 17.3 0.058 13.1 17.3 1.0 1 0 0 1 1 1 0 Nuclear protein Es2 LMBR1 PF04791.16 GBG73398.1 - 0.37 9.6 1.8 0.45 9.4 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC27 PF09507.10 GBG73398.1 - 1.2 8.4 30.3 1.6 8.0 30.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAM60A PF15396.6 GBG73398.1 - 2.6 8.0 13.4 2.1 8.3 12.4 1.3 1 1 0 1 1 1 0 Protein Family FAM60A PA26 PF04636.13 GBG73398.1 - 3.4 6.5 8.2 4.4 6.1 8.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Pkinase PF00069.25 GBG73399.1 - 5.4e-27 94.8 0.0 7.5e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG73399.1 - 5.1e-25 88.2 0.0 1.4e-24 86.8 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GBG73399.1 - 0.029 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP49_C PF12260.8 GBG73399.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kinase-like PF14531.6 GBG73399.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 GBG73399.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain rve PF00665.26 GBG73400.1 - 1.9e-13 50.6 0.0 4.8e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG73400.1 - 0.01 15.5 0.0 0.074 12.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG73401.1 - 1.1e-26 93.7 1.2 1e-25 90.6 1.0 2.4 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73401.1 - 6.9e-19 67.7 0.0 1.3e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73401.1 - 9.4e-08 32.3 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73402.1 - 3.8e-26 91.1 0.0 8.8e-26 89.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73402.1 - 1.2e-23 83.8 0.0 2e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73402.1 - 9.6e-23 80.5 0.0 2.4e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG73402.1 - 0.00015 21.5 0.0 0.0011 18.8 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73402.1 - 0.00021 21.8 0.0 0.00055 20.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73402.1 - 0.0016 19.0 0.0 0.0042 17.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A3 PF02160.15 GBG73402.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Cauliflower mosaic virus peptidase (A3) Asp_protease PF09668.10 GBG73402.1 - 0.0098 15.7 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease CHASE6_C PF17150.4 GBG73402.1 - 0.07 13.8 0.1 0.93 10.2 0.3 2.4 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain RVT_1 PF00078.27 GBG73403.1 - 1.6e-28 99.8 0.0 2.4e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73403.1 - 2.7e-23 81.9 0.0 9.5e-23 80.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73403.1 - 5e-20 71.8 0.0 1.2e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73403.1 - 1.6e-16 60.2 1.7 3.8e-16 58.9 1.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG73403.1 - 5.4e-08 33.4 0.0 1.2e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG73403.1 - 1.5e-07 31.6 0.0 4.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG73403.1 - 1.2e-06 28.9 0.0 3.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG73403.1 - 1.3e-06 28.2 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73403.1 - 0.0036 17.1 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG73404.1 - 5e-32 109.9 0.1 9.2e-32 109.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73404.1 - 9.8e-29 99.7 0.1 2.1e-28 98.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73404.1 - 2.3e-20 72.4 0.2 6e-20 71.1 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73404.1 - 5.5e-14 52.4 0.1 1.3e-13 51.2 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG73404.1 - 8.9e-05 22.6 0.0 0.00028 21.1 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG73404.1 - 0.0015 18.4 0.1 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG73404.1 - 0.058 13.1 0.5 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DUF2862 PF11061.8 GBG73404.1 - 0.1 12.5 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) Mcp5_PH PF12814.7 GBG73404.1 - 0.15 12.2 0.7 0.56 10.3 0.5 2.0 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology ZapB PF06005.12 GBG73406.1 - 0.043 14.3 1.7 1.5 9.3 1.7 2.1 1 1 0 1 1 1 0 Cell division protein ZapB RT_RNaseH_2 PF17919.1 GBG73407.1 - 4.7e-29 100.4 0.0 2.6e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73407.1 - 2e-25 89.1 0.0 5.2e-25 87.8 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73407.1 - 6.8e-25 87.9 0.1 1.1e-24 87.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG73408.1 - 6.9e-25 87.6 0.0 8.3e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73408.1 - 4.8e-09 36.1 0.0 6.3e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG73409.1 - 1.9e-06 28.1 0.2 3.6e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pkinase_Tyr PF07714.17 GBG73410.1 - 1.3e-32 113.2 0.0 2.8e-32 112.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG73410.1 - 3.2e-28 98.8 0.0 5.5e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 GBG73410.1 - 1.7e-09 37.3 19.2 4.1e-06 26.5 7.5 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GBG73410.1 - 2e-07 31.2 11.6 0.00014 22.2 6.3 3.5 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) Kdo PF06293.14 GBG73410.1 - 0.055 12.8 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_1 PF00560.33 GBG73410.1 - 0.082 13.5 13.5 0.35 11.6 1.6 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat CAP_N PF01213.19 GBG73410.1 - 3.3 7.1 10.8 4.1 6.8 2.6 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal RT_RNaseH_2 PF17919.1 GBG73411.1 - 1.7e-24 85.7 0.0 2.9e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73411.1 - 3e-22 78.9 0.0 5.3e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73411.1 - 2.1e-11 43.7 0.1 3.6e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.18 GBG73412.1 - 6.8e-37 127.2 0.1 1.2e-34 119.8 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Herpes_pp85 PF04637.12 GBG73412.1 - 1 7.7 3.9 0.2 10.0 0.1 1.6 1 1 1 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RT_RNaseH_2 PF17919.1 GBG73413.1 - 8.9e-52 173.3 0.0 1.9e-29 101.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73413.1 - 1.7e-40 137.5 0.1 1.3e-27 96.1 0.2 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73413.1 - 1.4e-11 44.6 0.0 4e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG73413.1 - 0.025 14.1 0.1 0.059 12.9 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CDH1_2_SANT_HL1 PF18375.1 GBG73413.1 - 0.062 14.0 0.3 6.8 7.5 0.0 3.3 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 RVT_1 PF00078.27 GBG73414.1 - 2e-20 73.3 0.0 3.1e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC27 PF09507.10 GBG73414.1 - 0.018 14.4 12.4 0.03 13.7 12.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BUD22 PF09073.10 GBG73414.1 - 0.029 13.8 24.7 0.047 13.0 24.7 1.3 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG73414.1 - 0.043 12.6 5.4 0.28 9.9 5.9 1.9 2 0 0 2 2 2 0 Presenilin Mpp10 PF04006.12 GBG73414.1 - 0.46 8.9 29.5 0.79 8.1 29.5 1.3 1 0 0 1 1 1 0 Mpp10 protein Pox_Ag35 PF03286.14 GBG73414.1 - 0.61 9.8 15.8 1.3 8.8 15.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.12 GBG73414.1 - 1.5 8.6 17.7 3.1 7.6 17.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 GBG73414.1 - 1.9 8.9 8.7 3.7 8.0 8.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Paf1 PF03985.13 GBG73414.1 - 2 7.3 31.6 3.6 6.5 31.6 1.3 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 GBG73414.1 - 2.5 6.1 41.1 3.6 5.6 41.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi V_ATPase_I PF01496.19 GBG73414.1 - 3.1 5.6 9.2 4.8 5.0 9.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SDA1 PF05285.12 GBG73414.1 - 4.3 6.7 33.5 0.11 12.0 26.5 1.8 2 0 0 2 2 2 0 SDA1 TFB6 PF17110.5 GBG73414.1 - 5.8 6.6 14.1 11 5.7 14.1 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2052 PF09747.9 GBG73414.1 - 6.4 6.9 28.8 0.084 13.0 21.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RXT2_N PF08595.11 GBG73414.1 - 7.4 6.6 17.1 14 5.6 17.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal SpoIIP PF07454.11 GBG73414.1 - 8.8 5.7 13.9 14 5.0 13.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tetraspanin PF00335.20 GBG73415.1 - 0.015 15.0 1.2 0.017 14.8 1.2 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2070 PF09843.9 GBG73415.1 - 0.2 9.9 14.6 0.23 9.7 14.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PhoLip_ATPase_C PF16212.5 GBG73415.1 - 0.78 9.4 11.3 0.99 9.1 11.3 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DDDD PF10161.9 GBG73415.1 - 1.2 8.9 0.0 1.2 8.9 0.0 3.8 3 2 0 3 3 3 0 Putative mitochondrial precursor protein TctB PF07331.11 GBG73415.1 - 4.5 7.6 15.5 29 4.9 17.0 1.6 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family RT_RNaseH_2 PF17919.1 GBG73416.1 - 3.9e-30 103.8 0.0 2.2e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73416.1 - 8e-29 100.0 0.0 1.8e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73416.1 - 2e-26 92.9 0.1 3.5e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73416.1 - 2.9e-16 59.3 0.0 6.5e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73416.1 - 2.2e-05 24.6 0.0 4.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF659 PF04937.15 GBG73417.1 - 1e-39 135.8 0.0 1.8e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73417.1 - 3.8e-05 23.4 0.1 8.4e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2065 PF09838.9 GBG73417.1 - 0.15 12.1 0.3 0.52 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) RVT_1 PF00078.27 GBG73419.1 - 8.9e-27 94.1 0.1 1.6e-26 93.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG73419.1 - 0.00018 21.3 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73419.1 - 0.0015 19.0 0.0 0.0042 17.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73419.1 - 0.0019 18.8 0.0 0.005 17.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease CDH1_2_SANT_HL1 PF18375.1 GBG73419.1 - 0.12 13.0 0.2 15 6.3 0.3 2.9 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 Nnf1 PF03980.14 GBG73419.1 - 3.7 8.0 8.2 2.1 8.8 5.1 2.3 2 0 0 2 2 2 0 Nnf1 RT_RNaseH_2 PF17919.1 GBG73420.1 - 2.3e-33 114.2 0.1 4.3e-33 113.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73420.1 - 4.5e-30 104.0 0.1 9.2e-30 103.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-RING_2 PF13639.6 GBG73420.1 - 1.9e-13 50.5 6.9 3.8e-13 49.5 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GBG73420.1 - 3.7e-10 39.4 3.1 7e-10 38.5 3.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GBG73420.1 - 3.7e-09 36.3 5.4 8.2e-09 35.2 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RVT_1 PF00078.27 GBG73420.1 - 6.4e-09 35.6 0.1 9.6e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4 PF00097.25 GBG73420.1 - 2.1e-07 30.7 4.2 3.8e-07 29.9 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG73420.1 - 3.1e-06 27.0 2.6 5.6e-06 26.1 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG73420.1 - 3.2e-06 27.0 5.2 6.2e-06 26.1 5.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GBG73420.1 - 1.1e-05 25.6 8.2 3.9e-05 23.9 8.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GBG73420.1 - 6.2e-05 22.9 3.7 0.00011 22.1 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GBG73420.1 - 9.1e-05 22.0 2.2 0.0002 20.9 2.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GBG73420.1 - 0.0075 16.3 1.5 0.0075 16.3 1.5 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_6 PF13912.6 GBG73420.1 - 0.017 15.1 0.1 0.017 15.1 0.1 2.2 2 0 0 2 2 1 0 C2H2-type zinc finger Prok-RING_4 PF14447.6 GBG73420.1 - 0.045 13.6 7.5 0.23 11.4 7.7 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 GBG73420.1 - 0.089 12.6 4.2 0.19 11.5 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GBG73420.1 - 0.29 11.3 8.6 0.83 9.9 6.4 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 GBG73420.1 - 1.8 8.7 3.7 7.1 6.8 3.7 2.1 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 GBG73420.1 - 3.6 8.0 8.3 0.19 12.1 1.8 2.1 2 0 0 2 2 2 0 RING-like domain DsrH PF04077.12 GBG73421.1 - 0.00013 22.0 0.7 31 4.8 0.0 6.1 2 2 5 8 8 8 1 DsrH like protein XendoU PF09412.10 GBG73421.1 - 0.14 11.3 14.9 0.16 11.1 3.5 3.2 1 1 3 4 4 4 0 Endoribonuclease XendoU PBP3 PF18056.1 GBG73421.1 - 0.23 11.6 4.5 12 6.1 0.1 3.6 1 1 1 4 4 4 0 Penicillin Binding Protein 3 Domain CstA PF02554.14 GBG73421.1 - 8.7 5.1 9.1 45 2.8 0.1 4.3 2 1 2 5 5 5 0 Carbon starvation protein CstA NST1 PF13945.6 GBG73422.1 - 4.2e-43 147.7 0.8 4.2e-43 147.7 0.8 5.5 5 1 0 5 5 5 1 Salt tolerance down-regulator Prok-RING_4 PF14447.6 GBG73423.1 - 1.4e-05 24.9 5.8 0.0031 17.3 3.0 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GBG73423.1 - 2.6e-05 24.0 5.4 0.00053 19.8 2.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG73423.1 - 0.022 14.7 4.7 0.062 13.3 4.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GBG73423.1 - 0.084 12.7 6.4 0.19 11.6 3.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 GBG73423.1 - 0.13 12.7 0.5 0.25 11.8 0.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 GBG73423.1 - 0.18 11.7 6.0 0.99 9.3 6.2 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG73423.1 - 3.7 8.0 10.4 47 4.4 10.4 2.6 1 1 0 1 1 1 0 Ring finger domain zf-CCHC PF00098.23 GBG73424.1 - 7.7e-09 35.2 1.9 1.4e-08 34.4 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG73424.1 - 0.00043 20.1 0.9 0.0013 18.5 0.9 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG73424.1 - 0.013 15.2 0.4 0.025 14.3 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG73424.1 - 0.058 13.2 1.4 0.11 12.3 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG73424.1 - 0.09 12.8 0.5 0.2 11.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle CLN3 PF02487.17 GBG73424.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 GBG73424.1 - 2.7 5.8 5.4 3 5.6 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-CCHC PF00098.23 GBG73425.1 - 0.00033 20.6 3.9 0.00069 19.6 3.9 1.6 1 0 0 1 1 1 1 Zinc knuckle AAA_23 PF13476.6 GBG73425.1 - 0.0029 18.1 3.5 0.0059 17.1 3.5 1.5 1 0 0 1 1 1 1 AAA domain VSG_B PF13206.6 GBG73425.1 - 0.0065 15.8 4.3 0.011 15.1 4.3 1.3 1 0 0 1 1 1 1 Trypanosomal VSG domain ALMT PF11744.8 GBG73425.1 - 0.076 11.8 5.8 0.11 11.3 5.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-CCHC_2 PF13696.6 GBG73425.1 - 0.09 12.6 1.7 0.16 11.8 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG73425.1 - 0.14 11.9 2.3 0.28 10.9 2.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger MCM3AP_GANP PF16769.5 GBG73425.1 - 0.2 9.8 8.0 0.27 9.5 8.0 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP TMPIT PF07851.13 GBG73425.1 - 0.26 10.5 9.7 0.38 9.9 9.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Tho2 PF11262.8 GBG73425.1 - 0.52 9.5 8.4 0.87 8.7 8.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Tmemb_161AB PF10268.9 GBG73425.1 - 0.83 8.2 3.8 1.2 7.8 3.8 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB V_ATPase_I PF01496.19 GBG73425.1 - 1.4 6.8 5.1 1.8 6.4 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 GBG73425.1 - 1.5 8.1 7.4 2.7 7.3 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EIIBC-GUT_N PF03612.14 GBG73425.1 - 3 7.5 4.9 9.8 5.9 4.9 1.9 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus LMBR1 PF04791.16 GBG73425.1 - 3.8 6.3 3.9 4.9 6.0 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PBP_sp32 PF07222.12 GBG73425.1 - 4.1 6.8 10.6 12 5.3 10.3 1.8 2 0 0 2 2 2 0 Proacrosin binding protein sp32 vATP-synt_E PF01991.18 GBG73425.1 - 6.1 6.2 19.9 0.56 9.6 13.9 2.0 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit GST_N PF02798.20 GBG73427.1 - 1.8e-14 53.8 0.0 2.2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GBG73427.1 - 1e-06 29.0 0.0 1.3e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG73427.1 - 1.6e-06 28.3 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Asp_protease_2 PF13650.6 GBG73429.1 - 0.066 13.9 0.0 0.24 12.1 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease Muted PF14942.6 GBG73429.1 - 1.2 9.5 15.2 0.021 15.2 7.4 2.0 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein RT_RNaseH_2 PF17919.1 GBG73431.1 - 9.2e-19 67.3 0.0 2.6e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73431.1 - 4.2e-12 46.1 0.0 7.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73431.1 - 1.7e-07 31.5 0.0 3.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GST_C PF00043.25 GBG73433.1 - 3.5e-12 46.4 0.0 4.6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GBG73433.1 - 2.2e-06 27.8 0.0 4.5e-06 26.8 0.0 1.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GBG73433.1 - 3.3e-05 23.8 0.0 5.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aminotran_1_2 PF00155.21 GBG73434.1 - 1.4e-87 294.2 0.0 1.8e-87 293.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zf-FCS PF06467.14 GBG73435.1 - 0.097 12.6 0.4 0.23 11.4 0.4 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CCHC PF00098.23 GBG73435.1 - 0.32 11.1 2.5 0.77 9.9 2.5 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG73436.1 - 1.9e-18 66.8 0.0 3.2e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73436.1 - 6.8e-05 22.6 0.2 0.00014 21.6 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Mpp10 PF04006.12 GBG73437.1 - 0.2 10.1 54.4 0.22 9.9 54.4 1.1 1 0 0 1 1 1 0 Mpp10 protein Pal1 PF08316.11 GBG73437.1 - 3.7 8.3 7.8 5.9 7.7 7.8 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Nop14 PF04147.12 GBG73437.1 - 6.2 4.9 59.5 7.5 4.6 59.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF5427 PF10310.9 GBG73437.1 - 9 5.1 32.2 12 4.7 32.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) NPR3 PF03666.13 GBG73437.1 - 10 4.8 30.5 12 4.6 30.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF659 PF04937.15 GBG73438.1 - 5e-26 91.4 0.0 8.9e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SDA1 PF05285.12 GBG73438.1 - 7.9 5.8 30.1 16 4.8 30.1 1.5 1 0 0 1 1 1 0 SDA1 RT_RNaseH PF17917.1 GBG73439.1 - 3.9e-24 85.0 0.3 1.2e-23 83.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73439.1 - 4.8e-15 55.4 0.0 1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG73439.1 - 6.2e-14 51.9 0.0 1.2e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73439.1 - 3e-13 50.0 0.0 1.2e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG73439.1 - 0.0003 21.0 0.0 0.00062 19.9 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG73440.1 - 1.2e-23 83.3 0.0 4.9e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73440.1 - 1.9e-23 82.4 0.0 6e-23 80.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG73440.1 - 4e-07 30.5 0.0 2.9e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG73440.1 - 4.2e-06 26.9 5.6 0.11 12.8 0.0 4.7 4 0 0 4 4 4 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG73440.1 - 6.4e-06 26.0 0.0 2.1e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73440.1 - 6.5e-06 26.7 0.0 2.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG73440.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CLZ PF16526.5 GBG73440.1 - 6 7.3 6.8 12 6.4 0.4 3.8 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RT_RNaseH_2 PF17919.1 GBG73441.1 - 1.3e-32 111.8 0.0 2.7e-18 65.9 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73441.1 - 6.6e-32 109.9 0.1 2.1e-22 79.4 0.1 3.7 2 1 1 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73441.1 - 5.7e-24 84.9 0.2 8.4e-22 77.8 0.1 2.7 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73441.1 - 8.8e-18 64.2 0.2 1.8e-17 63.2 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73441.1 - 2.2e-09 37.5 0.0 6.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG73441.1 - 3.7e-05 23.5 0.0 8.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73441.1 - 0.0022 18.6 0.0 0.0071 17.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-RVT PF13966.6 GBG73441.1 - 0.0064 17.2 10.8 0.012 16.3 8.0 2.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase gag-asp_proteas PF13975.6 GBG73441.1 - 0.06 13.9 0.0 0.22 12.1 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG73441.1 - 0.061 13.6 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger SlyX PF04102.12 GBG73441.1 - 0.14 12.7 4.2 0.28 11.8 0.3 3.2 3 0 0 3 3 2 0 SlyX RVT_1 PF00078.27 GBG73442.1 - 7.3e-28 97.6 0.2 2.2e-26 92.8 0.1 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73443.1 - 5.1e-34 116.3 0.0 1e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73443.1 - 9.1e-31 106.3 0.0 1.9e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73443.1 - 1.5e-30 106.3 0.1 2.8e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73443.1 - 5.1e-17 61.7 0.1 1.1e-16 60.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73443.1 - 9e-12 45.2 0.0 2.6e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG73443.1 - 0.059 13.6 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF4607 PF15380.6 GBG73444.1 - 0.087 12.3 5.8 0.37 10.2 5.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4607) DUF4607 PF15380.6 GBG73445.1 - 0.07 12.6 5.9 0.29 10.6 5.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4607) CSRNP_N PF16019.5 GBG73445.1 - 7 6.5 11.4 0.66 9.9 2.3 2.0 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus RVT_1 PF00078.27 GBG73446.1 - 7.6e-28 97.5 0.0 1e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73446.1 - 1.7e-13 50.5 0.0 3.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73446.1 - 2.1e-07 31.2 0.0 3.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2408 PF10303.9 GBG73447.1 - 0.0076 16.8 0.1 0.0076 16.8 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) Adaptin_binding PF10199.9 GBG73447.1 - 0.18 12.4 4.7 0.63 10.7 0.6 2.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 AAA_23 PF13476.6 GBG73447.1 - 1.5 9.2 4.7 8.5 6.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF659 PF04937.15 GBG73448.1 - 2.3e-41 141.2 0.0 4.1e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73448.1 - 5.3e-07 29.3 0.0 1.8e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG73449.1 - 1.9e-08 34.7 0.0 4.9e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73449.1 - 1.5e-07 32.0 0.0 3.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG73449.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG73449.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Med17 PF10156.9 GBG73449.1 - 0.017 13.8 0.5 0.031 13.0 0.5 1.3 1 0 0 1 1 1 0 Subunit 17 of Mediator complex RVP_2 PF08284.11 GBG73449.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4035 PF13227.6 GBG73450.1 - 0.11 12.2 0.2 0.33 10.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) PP28 PF10252.9 GBG73451.1 - 1.2e-28 99.4 19.7 1.2e-28 99.4 19.7 2.0 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 TPR_10 PF13374.6 GBG73451.1 - 1.3 9.0 4.7 0.87 9.5 1.3 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 GBG73452.1 - 0.024 14.9 0.1 0.075 13.3 0.1 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein PapC_C PF13953.6 GBG73452.1 - 1 9.2 32.3 14 5.6 1.1 8.5 1 1 10 11 11 11 0 PapC C-terminal domain RT_RNaseH PF17917.1 GBG73453.1 - 1.9e-22 79.5 0.0 3.7e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73453.1 - 7.9e-21 74.0 0.0 1.6e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73453.1 - 9e-19 67.3 0.3 1.9e-18 66.3 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73453.1 - 0.00044 20.4 0.1 0.00089 19.4 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Cytotoxic PF09000.10 GBG73453.1 - 0.021 15.1 1.2 1.2 9.5 0.2 2.3 2 0 0 2 2 2 0 Cytotoxic Claudin_2 PF13903.6 GBG73453.1 - 0.2 11.4 1.4 0.31 10.8 1.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DsrH PF04077.12 GBG73454.1 - 6.2e-06 26.2 1.1 22 5.3 0.0 7.1 4 3 4 8 8 8 1 DsrH like protein CstA PF02554.14 GBG73454.1 - 1.1 8.1 3.3 36 3.1 0.0 3.6 4 0 0 4 4 4 0 Carbon starvation protein CstA HTH_Tnp_1 PF01527.20 GBG73454.1 - 7.3 7.0 11.1 2 8.8 0.9 4.4 4 3 1 5 5 5 0 Transposase ATG_C PF09333.11 GBG73455.1 - 0.079 13.3 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain F-box PF00646.33 GBG73456.1 - 1.3e-07 31.3 0.6 2.4e-07 30.4 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG73456.1 - 9.2e-06 25.5 0.4 2.3e-05 24.2 0.4 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 GBG73457.1 - 3.8e-36 122.5 26.8 9.2e-08 32.6 0.6 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG73457.1 - 1.8e-17 63.4 10.8 6.4e-07 29.6 0.6 5.3 2 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG73457.1 - 0.01 15.2 0.0 0.034 13.5 0.0 1.7 2 0 0 2 2 2 1 WD40-like domain LDB19 PF13002.7 GBG73457.1 - 0.049 13.3 0.1 0.049 13.3 0.1 1.5 2 0 0 2 2 2 0 Arrestin_N terminal like VID27 PF08553.10 GBG73457.1 - 0.13 11.3 0.0 3.1 6.8 0.0 2.0 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain RT_RNaseH_2 PF17919.1 GBG73458.1 - 2.3e-19 69.3 0.0 6.1e-19 67.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73458.1 - 2.4e-17 63.1 0.0 6.2e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73458.1 - 2.2e-09 37.2 0.0 4.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73458.1 - 4.3e-06 26.9 0.0 1.4e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Pep_deformylase PF01327.21 GBG73458.1 - 0.067 12.8 2.4 0.17 11.5 2.4 1.6 1 0 0 1 1 1 0 Polypeptide deformylase zf-CCHC PF00098.23 GBG73458.1 - 4.1 7.7 6.8 1.1 9.5 3.3 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG73458.1 - 9.3 6.0 11.6 0.075 12.8 1.8 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger HSP70 PF00012.20 GBG73459.1 - 1.1e-154 516.0 2.9 3.8e-153 510.8 0.8 2.4 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 GBG73459.1 - 8.4e-09 34.7 0.1 8.7e-08 31.3 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DUF647 PF04884.14 GBG73461.1 - 6.5e-67 225.7 0.6 1.7e-66 224.3 0.1 1.9 2 0 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis Myb_DNA-bind_4 PF13837.6 GBG73463.1 - 7.7e-07 29.4 1.2 7.7e-07 29.4 1.2 2.3 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG73464.1 - 4.4e-07 30.2 2.1 4.4e-07 30.2 2.1 2.3 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain CATSPERG PF15064.6 GBG73465.1 - 7.9e-09 33.9 0.0 1.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Cation channel sperm-associated protein subunit gamma Ldh_1_N PF00056.23 GBG73467.1 - 3.4e-30 105.0 0.4 5.6e-30 104.3 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 GBG73467.1 - 2.4e-29 102.4 0.1 4.2e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Retrotrans_gag PF03732.17 GBG73468.1 - 0.0002 21.5 0.0 0.0002 21.5 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein zinc_ribbon_10 PF10058.9 GBG73468.1 - 0.018 14.7 0.1 0.084 12.6 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Myb_DNA-bind_4 PF13837.6 GBG73469.1 - 2.1e-09 37.6 0.5 4.5e-09 36.6 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain FAD-SLDH PF12318.8 GBG73470.1 - 0.002 18.2 0.1 1.4 9.0 0.1 2.2 2 0 0 2 2 2 2 Membrane bound FAD containing D-sorbitol dehydrogenase Rio2_N PF09202.11 GBG73470.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Rio2, N-terminal DUF2520 PF10728.9 GBG73470.1 - 0.24 11.1 1.8 0.59 9.9 1.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2520) DDE_Tnp_4 PF13359.6 GBG73471.1 - 1.9e-19 69.9 0.0 4.6e-19 68.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73471.1 - 1.8e-07 30.9 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG73471.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain RVT_1 PF00078.27 GBG73472.1 - 1.1e-29 103.5 0.5 1.2e-28 100.2 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73472.1 - 9.3e-18 64.1 0.2 1.9e-17 63.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73472.1 - 1.8e-07 31.3 0.0 7.5e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG73472.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG73472.1 - 0.018 15.3 0.1 0.018 15.3 0.1 3.7 4 0 0 4 4 4 0 Retrotransposon gag protein DUF4187 PF13821.6 GBG73472.1 - 0.45 10.3 6.5 0.068 13.0 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG73472.1 - 0.9 8.8 8.2 2.5 7.4 8.2 1.7 1 0 0 1 1 1 0 FAM76 protein Myb_DNA-bind_4 PF13837.6 GBG73473.1 - 7.5e-08 32.7 0.5 7.5e-08 32.7 0.5 2.2 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG73473.1 - 0.017 15.5 1.4 0.024 14.9 0.4 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG73473.1 - 0.031 14.3 2.8 0.083 13.0 2.8 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG73473.1 - 0.088 13.1 0.4 0.25 11.6 0.4 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain SNF2_N PF00176.23 GBG73474.1 - 5.3e-63 212.9 0.5 1e-62 211.9 0.2 1.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain DUF1086 PF06461.11 GBG73474.1 - 1.3e-29 102.8 0.0 3.3e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Chromo PF00385.24 GBG73474.1 - 4.4e-21 74.5 5.8 4.2e-13 49.0 0.1 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 GBG73474.1 - 2e-15 57.1 0.0 4.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1087 PF06465.13 GBG73474.1 - 7.9e-14 51.4 1.4 7.9e-14 51.4 1.4 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) ResIII PF04851.15 GBG73474.1 - 5.7e-09 36.2 0.0 1.3e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 GBG73474.1 - 1.5e-08 34.4 8.5 3.2e-08 33.3 8.5 1.5 1 0 0 1 1 1 1 PHD-finger HDA2-3 PF11496.8 GBG73474.1 - 3.2e-06 26.5 0.0 1.2e-05 24.7 0.0 1.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 CHDCT2 PF08074.11 GBG73474.1 - 0.00044 20.5 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain RT_RNaseH_2 PF17919.1 GBG73475.1 - 4.8e-30 103.5 0.1 1.4e-29 102.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73475.1 - 2e-26 92.3 0.5 5.9e-26 90.8 0.5 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73475.1 - 5.5e-17 62.1 0.0 2.2e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG73475.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 GBG73475.1 - 0.11 12.3 0.1 0.44 10.4 0.1 2.1 1 0 0 1 1 1 0 Integrase core domain Apc13p PF05839.11 GBG73475.1 - 0.15 12.3 0.5 1.2 9.3 0.5 2.4 2 0 0 2 2 2 0 Apc13p protein TMEM213 PF15192.6 GBG73478.1 - 0.043 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 TMEM213 family DUF896 PF05979.12 GBG73478.1 - 0.084 12.7 2.5 0.2 11.5 2.5 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Chordopox_A30L PF06015.12 GBG73479.1 - 0.033 14.0 0.2 0.071 13.0 0.2 1.5 1 0 0 1 1 1 0 Chordopoxvirus A30L protein DUF5595 PF18077.1 GBG73479.1 - 0.08 13.0 1.7 0.2 11.7 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) CRISPR_assoc PF08798.11 GBG73479.1 - 0.26 11.4 3.1 0.25 11.4 0.6 1.8 1 1 1 2 2 2 0 CRISPR associated protein DUF1542 PF07564.11 GBG73479.1 - 6.6 6.9 6.5 0.54 10.4 0.5 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) RVT_1 PF00078.27 GBG73480.1 - 3.9e-33 114.8 0.0 6.3e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73480.1 - 5.5e-19 68.1 0.0 2.2e-18 66.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73480.1 - 8.5e-09 35.6 0.0 2e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG73480.1 - 0.0071 16.6 0.0 0.075 13.3 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein PNMA PF14893.6 GBG73480.1 - 0.041 13.3 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 PNMA DUF1771 PF08590.10 GBG73481.1 - 5.3e-10 39.5 9.3 1.3e-09 38.3 9.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 GBG73481.1 - 3.3e-07 29.9 1.0 0.00015 21.4 0.1 3.2 4 0 0 4 4 4 2 CUE domain Smr PF01713.21 GBG73481.1 - 2.4e-06 27.8 0.0 6.2e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Smr domain DUF3410 PF11890.8 GBG73481.1 - 0.047 13.5 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) SOUL PF04832.12 GBG73482.1 - 1.8e-31 109.6 0.0 3.1e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 SOUL heme-binding protein Pec_lyase_C PF00544.19 GBG73485.1 - 3.6e-21 75.7 0.2 4.2e-20 72.2 0.2 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG73485.1 - 1.1e-06 28.6 1.8 5.8e-06 26.2 1.8 2.0 1 1 0 1 1 1 1 Right handed beta helix region Adeno_E1B_55K PF01696.17 GBG73485.1 - 0.086 11.5 0.4 0.12 11.1 0.4 1.1 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen NosD PF05048.13 GBG73485.1 - 0.14 11.4 0.4 0.51 9.6 0.1 1.8 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Pec_lyase_C PF00544.19 GBG73487.1 - 3.7e-21 75.7 0.2 4.3e-20 72.2 0.2 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG73487.1 - 1.4e-06 28.3 2.0 7.1e-06 25.9 2.0 2.1 1 1 0 1 1 1 1 Right handed beta helix region Adeno_E1B_55K PF01696.17 GBG73487.1 - 0.089 11.5 0.4 0.12 11.0 0.4 1.1 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen NosD PF05048.13 GBG73487.1 - 0.13 11.5 0.3 0.52 9.5 0.1 1.9 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Nup214_FG PF18617.1 GBG73487.1 - 1.9 9.1 9.0 0.81 10.2 4.7 2.6 2 0 0 2 2 2 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain Fes1 PF08609.10 GBG73488.1 - 2.8e-14 53.7 4.1 2.8e-14 53.7 4.1 2.8 3 1 1 4 4 4 1 Nucleotide exchange factor Fes1 Arm PF00514.23 GBG73488.1 - 6.5e-06 26.0 4.8 0.14 12.3 0.1 4.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GBG73488.1 - 0.00078 19.9 0.4 0.0051 17.3 0.1 2.6 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.22 GBG73488.1 - 0.0013 18.8 7.6 0.0038 17.4 0.1 3.9 4 0 0 4 4 4 1 HEAT repeat V-ATPase_H_C PF11698.8 GBG73488.1 - 0.0015 18.6 8.1 0.085 13.0 0.2 3.6 1 1 3 4 4 4 2 V-ATPase subunit H HEAT_2 PF13646.6 GBG73488.1 - 0.016 15.6 0.6 0.016 15.6 0.6 3.8 1 1 2 4 4 4 0 HEAT repeats DUF4363 PF14276.6 GBG73488.1 - 0.017 15.2 10.0 0.76 9.9 0.0 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF4363) Atx10homo_assoc PF09759.9 GBG73488.1 - 0.036 14.1 1.1 0.5 10.4 0.1 2.9 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain ILVD_EDD PF00920.21 GBG73488.1 - 0.061 11.9 0.2 0.14 10.8 0.1 1.5 2 0 0 2 2 2 0 Dehydratase family Cas_Csd1 PF09709.10 GBG73488.1 - 0.096 11.4 0.1 0.28 9.8 0.0 1.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csd1) VHS PF00790.19 GBG73488.1 - 0.11 12.4 1.7 2.7 7.8 0.3 2.9 1 1 1 2 2 2 0 VHS domain Lactamase_B PF00753.27 GBG73489.1 - 4.3e-11 43.2 0.1 1.1e-10 41.9 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 GBG73489.1 - 4.1e-10 39.4 1.5 2.3e-08 33.8 0.2 2.6 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 GBG73489.1 - 6.9e-05 22.5 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GBG73489.1 - 0.022 14.7 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase superfamily domain BUD22 PF09073.10 GBG73490.1 - 0.39 10.0 22.0 0.73 9.1 22.0 1.4 1 0 0 1 1 1 0 BUD22 PI3K_1B_p101 PF10486.9 GBG73490.1 - 2.8 5.6 11.3 4.3 5.0 11.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 GBG73490.1 - 3.7 4.5 11.5 5.3 4.0 11.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RT_RNaseH_2 PF17919.1 GBG73491.1 - 1e-30 105.7 0.0 2.1e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73491.1 - 7.1e-25 87.3 0.1 2.2e-24 85.7 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73491.1 - 3.2e-15 56.3 0.1 6.3e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRN3 PF05327.11 GBG73491.1 - 0.002 16.8 0.6 0.002 16.8 0.6 2.2 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Retrotrans_gag PF03732.17 GBG73491.1 - 0.038 14.3 0.2 0.15 12.4 0.2 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein PDEase_I PF00233.19 GBG73492.1 - 9.5e-70 235.0 0.0 2.6e-69 233.6 0.0 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 GBG73492.1 - 2.4e-15 56.6 0.0 4.5e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 GBG73492.1 - 0.00012 21.4 4.9 0.00012 21.4 4.9 1.9 2 0 0 2 2 2 1 Ion transport protein TPR_14 PF13428.6 GBG73492.1 - 0.023 15.5 0.2 0.2 12.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RR_TM4-6 PF06459.12 GBG73493.1 - 6.7 6.4 6.9 7.5 6.3 6.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVT_1 PF00078.27 GBG73494.1 - 2.2e-27 96.0 0.0 4.2e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73494.1 - 3.4e-23 81.9 0.0 5.9e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73494.1 - 2.9e-22 78.6 0.0 7.9e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG73494.1 - 2.4e-08 33.8 0.0 4.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73494.1 - 2.3e-07 31.3 0.0 5.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease mit_SMPDase PF14724.6 GBG73494.1 - 9.1e-07 27.3 0.2 0.18 9.7 0.0 3.4 4 0 0 4 4 4 3 Mitochondrial-associated sphingomyelin phosphodiesterase gag-asp_proteas PF13975.6 GBG73494.1 - 2.1e-05 25.0 0.0 4.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73494.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Glyco_hydro_77 PF02446.17 GBG73496.1 - 1e-144 482.9 0.0 1.4e-144 482.5 0.0 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase MID_MedPIWI PF18296.1 GBG73496.1 - 0.088 12.6 1.4 1.7 8.4 0.3 2.1 2 0 0 2 2 2 0 MID domain of medPIWI AIF_C PF14721.6 GBG73496.1 - 0.18 12.1 2.2 10 6.5 0.9 2.9 3 1 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CCDC53 PF10152.9 GBG73496.1 - 0.35 11.3 2.7 0.38 11.2 0.5 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3446 PF11928.8 GBG73496.1 - 0.8 10.0 24.3 1.8 8.9 22.6 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain eIF-3c_N PF05470.12 GBG73496.1 - 2.2 6.5 6.7 3.2 5.9 6.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tim54 PF11711.8 GBG73496.1 - 3.6 6.3 7.4 6.2 5.5 7.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pol_alpha_B_N PF08418.10 GBG73496.1 - 4.6 7.1 8.5 14 5.6 0.5 2.3 2 1 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Glyco_transf_29 PF00777.18 GBG73498.1 - 1.8e-33 116.1 1.7 8.3e-33 113.9 0.2 2.6 2 1 0 2 2 2 1 Glycosyltransferase family 29 (sialyltransferase) zf-LITAF-like PF10601.9 GBG73498.1 - 1.6 9.1 3.7 15 6.0 1.2 2.7 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Lyase_1 PF00206.20 GBG73499.1 - 4.8e-59 200.3 0.0 6.9e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 GBG73499.1 - 7.2e-52 174.3 0.0 1.6e-51 173.2 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal DDE_Tnp_IS66_C PF13817.6 GBG73499.1 - 0.052 13.8 0.4 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 IS66 C-terminal element RT_RNaseH_2 PF17919.1 GBG73501.1 - 5.8e-23 80.8 0.0 1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73501.1 - 8.7e-23 80.6 0.0 1.6e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73501.1 - 5.7e-08 32.6 0.4 3.9e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG73501.1 - 0.033 13.3 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 RVT_1 PF00078.27 GBG73502.1 - 1.3e-37 129.4 0.0 2.2e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG73502.1 - 3.1e-09 36.7 0.5 7.1e-09 35.5 0.5 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG73502.1 - 0.0008 19.3 0.0 0.0029 17.4 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Fer2 PF00111.27 GBG73503.1 - 0.0003 20.7 1.0 0.00033 20.5 1.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 GBG73503.1 - 0.004 17.2 5.0 0.023 14.7 5.0 1.9 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CDC45 PF02724.14 GBG73504.1 - 1.1 7.5 12.6 1.2 7.4 12.6 1.0 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG73504.1 - 9.6 6.2 17.9 10 6.2 17.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF4922 PF16269.5 GBG73506.1 - 1.2e-10 41.5 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) Mito_carr PF00153.27 GBG73507.1 - 3.4e-16 58.9 0.0 4.6e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein RVT_1 PF00078.27 GBG73508.1 - 8.2e-34 117.1 0.1 1.3e-33 116.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73508.1 - 1.8e-31 108.1 0.0 4e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73508.1 - 4.4e-30 104.1 0.0 9.1e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mito_carr PF00153.27 GBG73508.1 - 1.4e-10 41.0 0.2 1.5e-06 28.0 0.3 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein RVP_2 PF08284.11 GBG73508.1 - 1.3e-07 31.5 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73508.1 - 1.4e-06 28.8 0.0 2.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73508.1 - 7.7e-05 23.2 0.0 0.00022 21.7 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG73508.1 - 0.00096 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG73508.1 - 0.14 12.0 0.0 0.39 10.5 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease DUF4813 PF16072.5 GBG73509.1 - 6.7 6.3 19.5 12 5.5 19.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4813) TIM PF00121.18 GBG73510.1 - 2.6e-88 295.5 0.2 3.2e-88 295.2 0.2 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 GBG73510.1 - 0.042 13.3 0.0 0.16 11.5 0.0 1.8 2 1 0 2 2 2 0 CutC family MutS_V PF00488.21 GBG73512.1 - 3.7e-34 118.4 0.0 8.1e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain V Smr PF01713.21 GBG73512.1 - 6.9e-07 29.5 0.1 2.6e-06 27.7 0.1 2.1 1 0 0 1 1 1 1 Smr domain RNA_pol_3_Rpc31 PF11705.8 GBG73512.1 - 0.0031 17.8 0.8 0.0031 17.8 0.8 3.5 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 Caldesmon PF02029.15 GBG73512.1 - 0.93 8.2 31.6 1.5 7.5 5.4 2.5 2 0 0 2 2 2 0 Caldesmon Myc_N PF01056.18 GBG73512.1 - 3.4 7.5 16.0 0.056 13.3 6.0 2.5 2 0 0 2 2 2 0 Myc amino-terminal region DUF4834 PF16118.5 GBG73512.1 - 4.3 8.4 8.1 29 5.7 8.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RPA43_OB PF17875.1 GBG73512.1 - 5.4 7.7 11.5 3.8 8.1 5.2 2.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF4820 PF16091.5 GBG73512.1 - 5.9 6.2 19.6 0.088 12.2 10.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Pkinase_Tyr PF07714.17 GBG73513.1 - 4.1e-34 118.0 0.0 6.9e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG73513.1 - 1.4e-29 103.3 0.0 1.3e-19 70.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG73513.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PQQ_3 PF13570.6 GBG73513.1 - 0.0056 17.1 0.1 0.87 10.2 0.0 3.4 2 0 0 2 2 2 1 PQQ-like domain PTPRCAP PF15713.5 GBG73513.1 - 0.067 13.5 19.8 0.055 13.8 7.8 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Pkinase_fungal PF17667.1 GBG73513.1 - 0.18 10.5 0.0 0.36 9.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase CcmD PF04995.14 GBG73513.1 - 0.66 10.1 3.2 2.8 8.1 3.2 2.1 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Mito_fiss_reg PF05308.11 GBG73513.1 - 1.7 8.6 10.8 0.72 9.9 0.6 3.4 3 0 0 3 3 3 0 Mitochondrial fission regulator RT_RNaseH_2 PF17919.1 GBG73514.1 - 2.7e-27 94.7 0.0 5.7e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73514.1 - 7.5e-27 93.7 0.0 1.5e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73514.1 - 1.5e-16 60.6 0.0 3.4e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG73514.1 - 2.7e-05 24.0 3.2 2.7e-05 24.0 3.2 1.9 2 0 0 2 2 2 1 Zinc knuckle DUF2249 PF10006.9 GBG73514.1 - 0.016 15.1 0.0 0.89 9.5 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) Asp_protease_2 PF13650.6 GBG73514.1 - 0.021 15.5 0.0 0.048 14.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG73514.1 - 0.025 14.4 4.1 0.053 13.4 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 GBG73514.1 - 0.056 13.2 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73514.1 - 0.074 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CDC45 PF02724.14 GBG73514.1 - 3.8 5.7 14.7 6.7 4.9 14.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Pkinase_Tyr PF07714.17 GBG73515.1 - 8.7e-35 120.2 0.0 1.6e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG73515.1 - 2.5e-28 99.2 0.0 1e-19 70.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG73515.1 - 0.00028 20.9 0.0 0.00096 19.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family PQQ_3 PF13570.6 GBG73515.1 - 0.05 14.1 0.0 0.59 10.7 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain Pkinase_fungal PF17667.1 GBG73515.1 - 0.063 12.0 0.4 0.26 10.0 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase BSP_II PF05432.11 GBG73515.1 - 0.65 9.7 17.5 1.4 8.5 17.5 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.10 GBG73515.1 - 2.7 7.2 18.5 16 4.7 0.0 2.4 2 0 0 2 2 2 0 BUD22 SKG6 PF08693.10 GBG73515.1 - 8.5 5.9 11.6 21 4.6 11.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase_Tyr PF07714.17 GBG73516.1 - 9.9e-08 31.6 0.0 5.5e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG73516.1 - 3.5e-06 26.6 0.0 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Oxidored_q2 PF00420.24 GBG73516.1 - 0.074 12.7 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Pkinase_Tyr PF07714.17 GBG73517.1 - 4.1e-11 42.7 0.0 7.4e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG73517.1 - 4.1e-08 32.9 0.0 1.1e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain TAF1_subA PF14929.6 GBG73518.1 - 3e-13 50.0 0.0 8.6e-13 48.4 0.0 1.8 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_14 PF13428.6 GBG73518.1 - 0.00073 20.2 1.4 9 7.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG73518.1 - 0.019 15.5 0.0 5.5 7.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG73518.1 - 0.044 14.0 0.1 0.21 11.9 0.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GBG73518.1 - 0.12 12.1 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 TPR repeat Ank_2 PF12796.7 GBG73519.1 - 1.9e-34 118.1 0.0 5.1e-10 39.8 0.0 7.0 7 1 0 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG73519.1 - 7.3e-30 103.0 0.5 6e-10 39.4 0.1 5.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GBG73519.1 - 9.1e-29 98.6 3.5 3.5e-05 24.0 0.0 8.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 GBG73519.1 - 1.9e-24 83.0 3.1 0.028 15.0 0.0 9.5 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 GBG73519.1 - 2.8e-24 84.8 2.5 4.3e-08 33.3 0.2 8.3 5 2 2 7 7 7 5 Ankyrin repeats (many copies) SAM_2 PF07647.17 GBG73519.1 - 1.8e-17 63.2 7.2 0.0002 21.4 0.0 7.1 7 0 0 7 7 7 5 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GBG73519.1 - 2.9e-14 53.2 11.8 0.09 13.2 0.0 6.8 7 0 0 7 7 7 5 SAM domain (Sterile alpha motif) SR-25 PF10500.9 GBG73519.1 - 9.4e-06 25.4 9.0 9.4e-06 25.4 9.0 6.0 6 0 0 6 6 6 1 Nuclear RNA-splicing-associated protein SAM_PNT PF02198.16 GBG73519.1 - 0.73 9.8 16.2 26 4.9 0.0 5.7 7 0 0 7 7 7 0 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 GBG73519.1 - 1.6 9.0 13.2 1.3 9.3 0.0 5.3 6 0 0 6 6 6 0 Ste50p, sterile alpha motif DAGK_acc PF00609.19 GBG73520.1 - 1.3e-36 126.3 0.0 2.1e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 GBG73520.1 - 3.2e-21 75.2 0.0 1.3e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain SlyX PF04102.12 GBG73521.1 - 0.0024 18.4 0.7 0.0024 18.4 0.7 3.1 3 1 0 3 3 3 1 SlyX DnaJ PF00226.31 GBG73522.1 - 2.6e-20 72.3 0.1 4.6e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain CDC45 PF02724.14 GBG73522.1 - 0.35 9.1 12.4 0.49 8.6 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 GBG73523.1 - 0.0042 16.7 14.5 0.0042 16.7 14.5 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein PikAIV_N PF18605.1 GBG73523.1 - 0.017 14.7 2.2 0.039 13.5 2.2 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF5560 PF17715.1 GBG73523.1 - 0.22 10.9 1.9 0.74 9.2 1.9 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Integrase_H2C2 PF17921.1 GBG73525.1 - 1.4e-14 53.9 0.1 3.1e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG73525.1 - 0.00026 21.5 0.0 0.00058 20.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73525.1 - 0.00055 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG73525.1 - 0.0011 19.1 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger PRP1_N PF06424.12 GBG73525.1 - 0.83 10.0 24.5 4.1 7.8 1.2 2.9 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Nop14 PF04147.12 GBG73526.1 - 0.19 9.9 53.8 0.23 9.6 53.8 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG73526.1 - 1.1 8.6 57.7 1.1 8.6 57.7 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG73526.1 - 1.2 7.8 20.2 1.3 7.7 20.2 1.0 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 GBG73526.1 - 2.6 8.2 18.3 2.6 8.1 18.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SAPS PF04499.15 GBG73526.1 - 2.6 6.7 24.3 2.6 6.7 24.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 GBG73526.1 - 4 5.8 53.9 4.6 5.6 53.9 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF4045 PF13254.6 GBG73526.1 - 5.4 6.6 14.5 5.3 6.6 14.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TcdA_TcdB PF12919.7 GBG73527.1 - 0.13 11.5 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain AIRS_C PF02769.22 GBG73528.1 - 1.6e-26 93.3 0.0 3.1e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 GBG73528.1 - 6.7e-14 52.3 0.7 1.2e-13 51.5 0.7 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain RVT_1 PF00078.27 GBG73529.1 - 2.2e-27 96.0 0.1 5.4e-27 94.7 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73529.1 - 2e-20 72.6 0.2 4.6e-20 71.5 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG73529.1 - 8.8e-20 70.6 0.0 2.3e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73529.1 - 5.3e-14 52.4 0.0 1.4e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG73529.1 - 2.7e-08 34.4 0.0 7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG73529.1 - 5.3e-08 33.1 0.0 2.1e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG73529.1 - 9.3e-08 31.9 0.0 2.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73529.1 - 1.8e-06 28.4 0.0 6e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73529.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG73529.1 - 0.015 15.6 0.3 1.1 9.6 0.0 3.2 2 0 0 2 2 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG73529.1 - 0.021 15.0 0.2 0.067 13.4 0.2 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Cyclase_polyket PF04673.12 GBG73530.1 - 0.031 14.5 0.1 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 Polyketide synthesis cyclase Pkinase PF00069.25 GBG73531.1 - 4.1e-24 85.4 0.0 1.8e-21 76.7 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG73531.1 - 3.9e-11 42.7 0.0 6.4e-10 38.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG73531.1 - 0.0007 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 GBG73531.1 - 0.0046 16.6 0.0 0.0092 15.6 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 GBG73531.1 - 0.0063 15.3 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GBG73531.1 - 0.0083 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 GBG73531.1 - 0.0094 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 GBG73531.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Branch PF02485.21 GBG73533.1 - 1.1e-54 185.5 0.2 2.4e-54 184.4 0.2 1.5 1 0 0 1 1 1 1 Core-2/I-Branching enzyme RVT_1 PF00078.27 GBG73533.1 - 6.4e-28 97.8 0.3 1.5e-27 96.6 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG73533.1 - 0.0037 17.5 0.1 0.17 12.1 0.0 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein ADIP PF11559.8 GBG73533.1 - 0.013 15.6 1.3 0.029 14.5 1.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HrpB7 PF09486.10 GBG73533.1 - 0.23 11.9 4.6 0.42 11.0 3.7 1.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 GBG73534.1 - 0.084 12.9 1.7 0.33 11.0 1.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2116 PF09889.9 GBG73534.1 - 0.74 9.8 0.0 0.74 9.8 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) EOS1 PF12326.8 GBG73534.1 - 2.6 8.0 7.1 8.8 6.2 1.8 2.7 3 0 0 3 3 3 0 N-glycosylation protein Branch PF02485.21 GBG73535.1 - 5e-52 176.9 2.0 7e-52 176.4 2.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme HopA1 PF17914.1 GBG73535.1 - 0.18 11.6 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 HopA1 effector protein family PNTB PF02233.16 GBG73536.1 - 7.1e-172 572.5 24.2 7.1e-172 572.5 24.2 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 GBG73536.1 - 8.7e-68 227.8 0.1 1.7e-67 226.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 GBG73536.1 - 2.5e-39 134.7 0.1 4.9e-39 133.7 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 GBG73536.1 - 6.1e-31 106.7 0.7 6.1e-31 106.7 0.7 3.6 3 1 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Pyr_redox_2 PF07992.14 GBG73536.1 - 0.0003 20.1 0.1 0.00056 19.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG73536.1 - 0.0043 17.6 0.3 0.02 15.5 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GBG73536.1 - 0.048 13.0 0.0 1.8 7.9 0.0 3.2 3 1 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 GBG73536.1 - 0.11 12.3 0.1 3.6 7.3 0.1 3.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain HEAT PF02985.22 GBG73536.1 - 0.15 12.4 0.1 0.61 10.5 0.1 2.1 1 0 0 1 1 1 0 HEAT repeat DUF624 PF04854.14 GBG73536.1 - 4.2 7.5 6.2 11 6.3 0.7 3.1 1 1 0 2 2 2 0 Protein of unknown function, DUF624 Presenilin PF01080.17 GBG73537.1 - 0.019 13.8 19.1 0.019 13.8 19.1 1.1 1 0 0 1 1 1 0 Presenilin SpoIIIAH PF12685.7 GBG73537.1 - 0.065 13.1 19.5 0.08 12.8 19.5 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 GBG73537.1 - 0.099 10.8 51.2 0.11 10.6 51.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG73537.1 - 0.1 12.0 48.1 0.13 11.7 48.1 1.1 1 0 0 1 1 1 0 SDA1 DUF2151 PF10221.9 GBG73537.1 - 0.11 11.1 15.9 0.12 11.0 15.9 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Caldesmon PF02029.15 GBG73537.1 - 0.14 10.9 41.6 0.15 10.8 41.6 1.0 1 0 0 1 1 1 0 Caldesmon Mpp10 PF04006.12 GBG73537.1 - 0.23 9.9 49.9 0.28 9.6 49.9 1.0 1 0 0 1 1 1 0 Mpp10 protein Zip PF02535.22 GBG73537.1 - 1.4 8.1 14.9 1.6 7.8 14.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BORG_CEP PF14957.6 GBG73537.1 - 2.6 9.2 16.2 3.5 8.8 16.2 1.1 1 0 0 1 1 1 0 Cdc42 effector MDM10 PF12519.8 GBG73537.1 - 4.2 6.1 12.3 4.4 6.1 12.3 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CCSAP PF15748.5 GBG73537.1 - 4.2 7.5 26.3 5.3 7.1 26.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 GBG73537.1 - 7.6 4.7 39.4 11 4.2 39.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.6 GBG73537.1 - 9.8 5.7 23.1 11 5.5 23.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) potato_inhibit PF00280.18 GBG73539.1 - 2.5e-20 72.9 0.0 4.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Potato inhibitor I family 2OG-FeII_Oxy_3 PF13640.6 GBG73539.1 - 1.1e-13 51.9 0.1 3.5e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 GBG73539.1 - 8.3e-05 23.2 0.0 0.00019 22.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 GBG73539.1 - 0.018 14.6 0.1 2.5 7.6 0.0 3.0 2 1 0 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA SET PF00856.28 GBG73540.1 - 9.3e-12 45.6 0.3 9.3e-12 45.6 0.3 3.5 3 1 0 3 3 3 1 SET domain zf-MYND PF01753.18 GBG73540.1 - 1.6e-09 37.6 11.8 1.6e-09 37.6 11.8 3.2 3 0 0 3 3 3 1 MYND finger Ecl1 PF12855.7 GBG73540.1 - 0.045 14.9 19.7 0.29 12.3 0.5 3.1 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins Macoilin PF09726.9 GBG73540.1 - 0.11 11.0 22.4 0.0056 15.3 12.9 2.2 2 0 0 2 2 2 0 Macoilin family SDA1 PF05285.12 GBG73540.1 - 0.77 9.1 45.1 5 6.5 24.0 3.2 3 0 0 3 3 3 0 SDA1 DUF2052 PF09747.9 GBG73540.1 - 1.3 9.1 40.4 2.7 8.1 0.3 3.5 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) BUD22 PF09073.10 GBG73540.1 - 1.6 8.0 43.9 2.1 7.6 13.5 3.1 3 0 0 3 3 3 0 BUD22 zf-C6H2 PF15801.5 GBG73540.1 - 1.8 8.9 9.9 6.4 7.2 6.7 2.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PTPRCAP PF15713.5 GBG73540.1 - 2.2 8.6 42.4 1.2 9.4 4.3 3.6 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated CPSF100_C PF13299.6 GBG73540.1 - 6 7.0 21.0 2.8 8.1 1.4 3.5 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Nha1_C PF08619.10 GBG73540.1 - 9.6 5.3 33.8 2.2 7.4 7.3 3.2 3 0 0 3 3 3 0 Alkali metal cation/H+ antiporter Nha1 C terminus Caleosin PF05042.13 GBG73542.1 - 1e-72 243.6 0.1 1.2e-72 243.3 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 GBG73542.1 - 3e-05 23.6 1.5 0.013 15.3 0.4 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 GBG73542.1 - 0.00011 22.6 0.6 0.00072 20.0 0.6 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GBG73542.1 - 0.00085 18.7 4.2 0.021 14.4 0.7 3.1 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 GBG73542.1 - 0.0028 17.4 1.0 0.034 14.0 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 GBG73542.1 - 0.7 9.5 6.1 12 5.6 0.1 3.3 3 0 0 3 3 3 0 EF hand Afi1 PF07792.12 GBG73543.1 - 0.014 15.9 2.9 0.073 13.6 2.9 2.1 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SDA1 PF05285.12 GBG73543.1 - 0.069 12.6 28.7 0.088 12.2 28.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG73543.1 - 0.64 8.2 22.5 0.8 7.9 22.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG73543.1 - 0.8 7.8 30.5 1.2 7.2 30.5 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG73543.1 - 5.1 6.3 36.3 7.5 5.8 36.3 1.1 1 0 0 1 1 1 0 BUD22 MCM_bind PF09739.9 GBG73543.1 - 5.7 5.3 8.5 7.5 4.9 8.5 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Cwf_Cwc_15 PF04889.12 GBG73543.1 - 6.2 6.5 27.5 8.8 6.0 27.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 GBG73543.1 - 7.3 5.3 13.2 9 4.9 13.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Caleosin PF05042.13 GBG73544.1 - 1.2e-72 243.4 0.1 1.4e-72 243.1 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 GBG73544.1 - 2.8e-05 23.7 1.5 0.013 15.3 0.4 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 GBG73544.1 - 0.00012 22.5 0.6 0.001 19.5 0.8 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GBG73544.1 - 0.00084 18.7 4.2 0.021 14.4 0.7 3.1 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 GBG73544.1 - 0.0029 17.4 1.1 0.035 14.0 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 GBG73544.1 - 0.7 9.5 6.1 12 5.6 0.1 3.3 3 0 0 3 3 3 0 EF hand DDE_Tnp_4 PF13359.6 GBG73545.1 - 1.6e-18 66.8 0.0 2.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73545.1 - 1.9e-08 34.2 0.0 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Nop14 PF04147.12 GBG73545.1 - 6.8 4.8 9.3 9.7 4.3 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family OTU PF02338.19 GBG73547.1 - 6.4e-24 84.9 0.0 1.1e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DNA_topoisoIV PF00521.20 GBG73548.1 - 7.1e-147 489.7 0.0 9e-147 489.4 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 GBG73548.1 - 8.2e-55 182.1 4.8 8.1e-09 34.8 0.3 6.6 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller PPP4R2 PF09184.11 GBG73548.1 - 0.26 10.9 7.0 0.14 11.7 0.2 2.4 2 0 0 2 2 2 0 PPP4R2 RT_RNaseH_2 PF17919.1 GBG73549.1 - 1.5e-34 118.0 0.0 2.8e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73549.1 - 5e-31 107.1 0.0 9.7e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73549.1 - 4.2e-23 82.0 0.1 8.5e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73549.1 - 2.3e-16 59.6 0.5 4.7e-16 58.6 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73549.1 - 7e-08 32.7 0.2 5e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain LRAT PF04970.13 GBG73551.1 - 8.5e-19 68.1 0.0 1.5e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Myb_DNA-bind_4 PF13837.6 GBG73551.1 - 2.5e-07 31.0 0.0 6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF5607 PF18355.1 GBG73551.1 - 0.082 13.4 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) RVT_1 PF00078.27 GBG73553.1 - 1.2e-22 80.5 0.1 2e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG73553.1 - 5.1e-07 30.2 0.0 1.1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73553.1 - 9e-07 29.4 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73553.1 - 7.8e-06 25.7 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG73553.1 - 4.7e-05 23.6 0.1 0.00014 22.1 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG73553.1 - 0.00057 19.7 0.0 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG73553.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ubiquitin PF00240.23 GBG73554.1 - 0.043 13.6 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family DivIC PF04977.15 GBG73554.1 - 0.68 9.7 7.0 0.47 10.3 0.7 3.3 3 0 0 3 3 3 0 Septum formation initiator Cep57_CLD_2 PF14197.6 GBG73554.1 - 1.5 8.9 15.5 0.094 12.8 7.2 3.3 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 HALZ PF02183.18 GBG73554.1 - 3.5 7.9 7.8 2.2 8.6 0.4 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper LRAT PF04970.13 GBG73555.1 - 1.4e-28 99.8 0.0 2.9e-28 98.7 0.0 1.5 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 GBG73555.1 - 0.02 14.7 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain RVT_1 PF00078.27 GBG73556.1 - 6e-33 114.2 0.1 1.1e-32 113.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73556.1 - 4e-31 107.0 0.0 9e-31 105.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73556.1 - 2.2e-30 105.1 0.0 4.3e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73556.1 - 2.7e-10 40.2 0.0 6.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73556.1 - 0.083 13.1 0.0 0.35 11.1 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG73556.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SbcD_C PF12320.8 GBG73556.1 - 0.13 12.6 0.3 2.6 8.4 0.0 2.7 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain RVP_2 PF08284.11 GBG73556.1 - 0.21 11.4 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1664 PF07889.12 GBG73557.1 - 0.023 14.7 0.3 0.053 13.6 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 GBG73557.1 - 0.051 13.9 0.4 0.22 11.8 0.0 2.2 2 1 0 2 2 2 0 Retrotransposon gag protein PI3K_P85_iSH2 PF16454.5 GBG73557.1 - 0.056 13.0 1.1 0.14 11.7 0.5 1.8 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PspA_IM30 PF04012.12 GBG73557.1 - 0.085 12.4 2.1 0.12 11.9 2.1 1.2 1 0 0 1 1 1 0 PspA/IM30 family TMF_DNA_bd PF12329.8 GBG73557.1 - 0.092 12.8 0.3 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 GBG73557.1 - 0.1 12.6 2.5 0.17 11.9 1.7 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2730 PF10805.8 GBG73557.1 - 0.13 12.4 0.2 0.66 10.1 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) FUSC PF04632.12 GBG73557.1 - 0.13 10.8 0.6 0.18 10.3 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 GBG73557.1 - 0.13 12.5 2.0 0.18 12.0 2.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 GBG73557.1 - 0.26 11.9 3.9 0.63 10.7 1.9 2.6 1 1 2 3 3 3 0 SlyX Lipoxygenase PF00305.19 GBG73558.1 - 5.7e-124 415.0 1.6 2.2e-119 399.8 0.1 2.7 1 1 1 2 2 2 2 Lipoxygenase PDE8 PF08629.10 GBG73558.1 - 0.073 13.1 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 PDE8 phosphodiesterase RT_RNaseH PF17917.1 GBG73560.1 - 1.7e-22 79.7 0.0 3.3e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73560.1 - 2.4e-22 78.9 0.0 4.8e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73560.1 - 1.7e-14 53.7 0.0 4.8e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73560.1 - 5.5e-06 26.6 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG73560.1 - 0.00044 20.7 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG73560.1 - 0.059 13.7 0.5 0.24 11.7 0.5 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG73561.1 - 0.034 14.2 1.1 0.064 13.4 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle BRI3BP PF14965.6 GBG73561.1 - 7.8 6.0 5.4 61 3.1 0.0 2.7 3 0 0 3 3 3 0 Negative regulator of p53/TP53 kleA_kleC PF17383.2 GBG73562.1 - 0.12 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Retrotrans_gag PF03732.17 GBG73563.1 - 0.0083 16.4 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG73564.1 - 8e-30 102.8 0.0 1.4e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73564.1 - 1.1e-29 102.8 0.0 2.4e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LRRNT_2 PF08263.12 GBG73564.1 - 9.4e-05 22.6 0.1 0.00035 20.8 0.1 2.1 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Phage_GPO PF05929.11 GBG73564.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG73564.1 - 0.045 13.3 0.1 0.091 12.3 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG73566.1 - 1.5e-25 90.0 0.0 2.4e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG73566.1 - 2.1e-05 24.3 0.1 4.1e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG73567.1 - 0.00059 19.6 0.8 0.0017 18.1 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Lipin_mid PF16876.5 GBG73567.1 - 0.033 14.3 0.3 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain YbaJ PF10757.9 GBG73567.1 - 0.065 13.8 0.4 2.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Biofilm formation regulator YbaJ Yae1_N PF09811.9 GBG73569.1 - 0.00021 20.9 0.0 0.0033 17.1 0.0 2.8 1 1 1 2 2 2 1 Essential protein Yae1, N terminal Pkinase PF00069.25 GBG73570.1 - 1.6e-48 165.4 0.0 3.4e-48 164.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG73570.1 - 2.5e-48 164.6 0.0 8.1e-48 163.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RT_RNaseH_2 PF17919.1 GBG73570.1 - 2.6e-21 75.5 0.0 5.5e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73570.1 - 1.2e-19 70.5 0.1 2.3e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73570.1 - 5.5e-09 36.0 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain LRR_8 PF13855.6 GBG73570.1 - 3.1e-08 33.2 2.5 7.7e-08 32.0 2.5 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GBG73570.1 - 0.00021 21.6 3.9 0.0011 19.3 0.9 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) APH PF01636.23 GBG73570.1 - 0.0063 16.5 0.1 0.43 10.4 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family LRR_1 PF00560.33 GBG73570.1 - 0.0081 16.6 1.1 4.3 8.3 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat ABC1 PF03109.16 GBG73570.1 - 0.13 12.5 0.0 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 ABC1 family Nop14 PF04147.12 GBG73571.1 - 0.021 13.1 8.1 0.025 12.8 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG73571.1 - 0.17 11.3 10.3 0.21 11.0 10.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG73571.1 - 0.28 9.4 8.5 0.35 9.1 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 GBG73571.1 - 0.52 10.6 13.8 1 9.6 13.8 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated IPK PF03770.16 GBG73573.1 - 2.8e-37 128.5 0.2 4.9e-20 72.2 0.0 3.2 3 1 0 3 3 3 2 Inositol polyphosphate kinase YL1 PF05764.13 GBG73573.1 - 0.004 17.3 9.4 0.0085 16.2 9.4 1.5 1 0 0 1 1 1 1 YL1 nuclear protein UPF0239 PF06783.11 GBG73573.1 - 0.017 15.3 6.0 0.05 13.8 6.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) NST1 PF13945.6 GBG73573.1 - 0.12 12.5 8.5 0.2 11.7 8.5 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator AIF_C PF14721.6 GBG73573.1 - 0.28 11.5 1.8 0.55 10.6 1.8 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CDC45 PF02724.14 GBG73573.1 - 0.38 9.0 8.5 0.52 8.5 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 GBG73573.1 - 0.59 8.6 7.1 0.89 8.0 7.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 GBG73573.1 - 1.1 7.9 3.4 1.7 7.3 3.4 1.2 1 0 0 1 1 1 0 Presenilin Paf1 PF03985.13 GBG73573.1 - 2.6 7.0 10.6 20 4.0 11.4 1.8 2 0 0 2 2 2 0 Paf1 YqfQ PF14181.6 GBG73573.1 - 3.4 7.8 9.6 7.1 6.8 9.6 1.5 1 0 0 1 1 1 0 YqfQ-like protein zf-CCCH_3 PF15663.5 GBG73574.1 - 6e-15 55.4 5.0 5.1e-11 42.8 0.6 3.1 3 0 0 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 GBG73574.1 - 1.3e-08 35.0 17.9 0.0014 19.0 1.5 3.4 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 GBG73574.1 - 6.6e-07 29.2 21.9 1.2e-06 28.3 1.0 4.1 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH PF00642.24 GBG73574.1 - 1.3e-05 25.0 11.9 0.00042 20.1 0.3 3.5 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GBG73574.1 - 3.5e-05 23.5 14.6 0.0093 15.7 0.7 3.5 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 GBG73574.1 - 0.00021 21.9 0.8 0.00021 21.9 0.8 4.2 3 1 1 4 4 4 2 Torus domain Retrotrans_gag PF03732.17 GBG73575.1 - 0.0032 17.7 0.8 0.054 13.8 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein HHH_9 PF17674.1 GBG73575.1 - 0.49 11.3 2.6 46 5.0 1.2 2.8 1 1 1 2 2 2 0 HHH domain DUF5401 PF17380.2 GBG73575.1 - 1 7.3 5.3 1.8 6.5 5.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Chorion_2 PF03964.15 GBG73576.1 - 0.011 16.6 0.7 0.019 15.8 0.7 1.5 1 0 0 1 1 1 0 Chorion family 2 DUF4378 PF14309.6 GBG73579.1 - 4.5e-26 92.2 0.0 1e-25 91.0 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4378) bZIP_2 PF07716.15 GBG73579.1 - 8.9 6.5 7.4 2 8.5 2.5 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DUF4378 PF14309.6 GBG73580.1 - 4.5e-26 92.2 0.0 1e-25 91.0 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4378) bZIP_2 PF07716.15 GBG73580.1 - 8.9 6.5 7.4 2 8.5 2.5 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Filament PF00038.21 GBG73581.1 - 0.056 13.0 3.3 3.3 7.2 0.1 2.0 1 1 1 2 2 2 0 Intermediate filament protein gag-asp_proteas PF13975.6 GBG73582.1 - 1.6e-05 25.4 0.0 4.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73582.1 - 0.00031 21.3 0.0 0.00078 20.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease TP2 PF01254.18 GBG73582.1 - 0.0021 18.7 2.3 0.0035 17.9 2.3 1.3 1 0 0 1 1 1 1 Nuclear transition protein 2 RVT_1 PF00078.27 GBG73583.1 - 7.7e-09 35.4 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG73583.1 - 0.055 13.2 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Nbs1_C PF08599.10 GBG73583.1 - 0.2 11.8 2.0 0.43 10.7 2.0 1.5 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 U3_snoRNA_assoc PF08297.11 GBG73583.1 - 6.3 7.6 10.0 3.1 8.5 7.8 1.6 2 0 0 2 2 2 0 U3 snoRNA associated CDC45 PF02724.14 GBG73583.1 - 7.2 4.8 7.5 10 4.2 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 GBG73583.1 - 8.4 6.9 7.3 77 3.8 5.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PKcGMP_CC PF16808.5 GBG73584.1 - 0.033 14.0 0.3 0.033 14.0 0.3 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF724 PF05266.14 GBG73584.1 - 0.084 12.7 12.5 0.13 12.1 6.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) bZIP_1 PF00170.21 GBG73584.1 - 0.26 11.4 3.9 0.4 10.8 0.7 2.9 2 0 0 2 2 2 0 bZIP transcription factor Mo25 PF08569.11 GBG73584.1 - 0.52 9.6 2.4 0.81 9.0 2.4 1.2 1 0 0 1 1 1 0 Mo25-like Med8 PF10232.9 GBG73584.1 - 3.4 7.2 7.0 1.8 8.1 3.5 2.3 2 1 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 FlxA PF14282.6 GBG73584.1 - 3.7 7.6 6.7 14 5.7 6.7 2.1 1 0 0 1 1 1 0 FlxA-like protein RT_RNaseH_2 PF17919.1 GBG73586.1 - 4.7e-19 68.3 0.0 1.5e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73586.1 - 5.8e-16 58.7 0.0 1.4e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73586.1 - 3.1e-05 23.6 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4590 PF15257.6 GBG73587.1 - 0.068 13.1 0.5 0.096 12.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) KH_1 PF00013.29 GBG73588.1 - 2.6e-46 155.3 13.9 2.2e-17 62.6 1.9 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GBG73588.1 - 1.8e-11 43.7 9.7 0.0037 17.1 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GBG73588.1 - 2e-07 30.8 10.9 0.0063 16.4 0.3 4.1 5 0 0 5 5 5 3 KH domain KH_5 PF13184.6 GBG73588.1 - 4e-07 30.0 12.6 0.0017 18.4 0.8 3.4 3 0 0 3 3 3 3 NusA-like KH domain DUF370 PF04025.12 GBG73588.1 - 1.8 8.8 4.7 0.81 9.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF370) ATG16 PF08614.11 GBG73589.1 - 0.0019 18.5 18.4 0.0019 18.5 18.4 2.8 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 GBG73589.1 - 0.028 14.8 4.4 0.028 14.8 4.4 3.7 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 GBG73589.1 - 0.6 10.1 10.2 0.74 9.8 8.6 2.1 2 0 0 2 2 2 0 Laminin Domain II FAM76 PF16046.5 GBG73589.1 - 0.66 9.3 26.3 2 7.7 17.9 2.2 2 0 0 2 2 2 0 FAM76 protein Macoilin PF09726.9 GBG73589.1 - 7.2 5.0 21.6 0.53 8.8 13.3 2.0 2 0 0 2 2 2 0 Macoilin family Dimer_Tnp_hAT PF05699.14 GBG73590.1 - 1.4e-09 37.6 0.0 3.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Integrase_H2C2 PF17921.1 GBG73590.1 - 0.0032 17.6 4.5 0.058 13.5 0.0 3.6 4 0 0 4 4 4 2 Integrase zinc binding domain BNIP3 PF06553.12 GBG73591.1 - 0.0058 16.3 2.2 0.0089 15.7 2.2 1.5 1 0 0 1 1 1 1 BNIP3 AAA PF00004.29 GBG73592.1 - 7.9e-19 68.4 0.1 6.8e-15 55.7 0.0 2.8 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG73592.1 - 1.5e-10 40.7 0.0 3.8e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GBG73592.1 - 0.00038 20.9 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GBG73592.1 - 0.00097 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GBG73592.1 - 0.0028 17.8 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GBG73592.1 - 0.0033 17.8 0.0 0.0095 16.3 0.0 1.8 2 0 0 2 2 1 1 RNA helicase RuvB_N PF05496.12 GBG73592.1 - 0.01 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 GBG73592.1 - 0.015 15.6 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG73592.1 - 0.018 15.6 0.0 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GBG73592.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GBG73592.1 - 0.047 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 GBG73592.1 - 0.052 12.7 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 GBG73592.1 - 0.061 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GBG73592.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GBG73592.1 - 0.073 12.8 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GBG73592.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 GBG73592.1 - 0.16 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CBFD_NFYB_HMF PF00808.23 GBG73592.1 - 0.21 11.9 0.6 1.3 9.4 0.0 2.6 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-CCHC PF00098.23 GBG73593.1 - 4.6e-05 23.3 2.1 4.6e-05 23.3 2.1 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG73593.1 - 0.051 13.3 2.8 0.059 13.1 0.9 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG73593.1 - 0.12 12.2 0.8 0.25 11.1 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle FYDLN_acid PF09538.10 GBG73593.1 - 0.99 10.1 18.0 6.6 7.5 3.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Profilin PF00235.19 GBG73594.1 - 1.8e-36 125.2 0.0 2e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Profilin RT_RNaseH PF17917.1 GBG73595.1 - 1.3e-25 89.7 0.0 1.9e-24 85.9 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73595.1 - 1.4e-22 79.6 0.0 4.4e-22 78.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73595.1 - 3.1e-11 43.2 0.0 5.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG73595.1 - 4e-06 27.3 0.1 1.3e-05 25.6 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73595.1 - 4e-05 23.4 0.0 8.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG73595.1 - 6.8e-05 23.4 0.1 0.00022 21.8 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG73596.1 - 1.5e-29 101.9 0.0 3.5e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73596.1 - 5.1e-26 91.0 0.0 9.7e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73596.1 - 7.3e-15 55.1 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG73599.1 - 3.6e-39 134.1 0.0 1e-38 132.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73599.1 - 1.7e-06 27.8 0.1 2.9e-05 23.8 0.2 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG73599.1 - 7.9 6.7 19.1 0.1 12.6 3.9 3.3 3 0 0 3 3 3 0 AT hook motif eIF-5_eIF-2B PF01873.17 GBG73600.1 - 2.8e-34 117.5 0.3 3.2e-34 117.3 0.3 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 GBG73600.1 - 0.01 15.3 0.3 0.025 14.1 0.2 1.7 1 1 1 2 2 2 0 TFIIB zinc-binding HisG PF01634.18 GBG73601.1 - 1.2e-38 132.6 0.0 1.9e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 GBG73601.1 - 3.6e-14 52.7 0.0 1.1e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 HisG, C-terminal domain Polysacc_synt_2 PF02719.15 GBG73601.1 - 0.025 13.7 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Cwf_Cwc_15 PF04889.12 GBG73602.1 - 0.0094 15.7 8.1 0.024 14.4 4.7 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GBG73602.1 - 0.01 15.2 4.9 0.021 14.2 4.9 1.6 1 0 0 1 1 1 1 NOA36 protein ERF PF04404.12 GBG73602.1 - 6 6.7 5.3 12 5.7 5.3 1.5 1 0 0 1 1 1 0 ERF superfamily DNA_pol_phi PF04931.13 GBG73602.1 - 6.1 4.8 9.2 9.8 4.1 9.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Toprim_4 PF13662.6 GBG73603.1 - 2.3e-18 66.4 0.0 4.7e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DnaB_C PF03796.15 GBG73603.1 - 1e-11 44.7 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_2 PF13155.6 GBG73603.1 - 6.6e-08 32.9 0.0 1.6e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Toprim-like AAA_25 PF13481.6 GBG73603.1 - 5.4e-07 29.4 0.0 3e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain Toprim PF01751.22 GBG73603.1 - 3.6e-06 27.1 0.0 3.4e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Toprim domain Toprim_3 PF13362.6 GBG73603.1 - 0.00031 21.0 0.7 0.0053 17.1 0.1 2.3 2 0 0 2 2 2 1 Toprim domain AAA_29 PF13555.6 GBG73603.1 - 0.085 12.6 0.4 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 GBG73603.1 - 0.1 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNase_T PF00929.24 GBG73604.1 - 0.00015 22.4 0.0 0.00027 21.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DUF1619 PF07773.11 GBG73605.1 - 1.2e-48 166.7 0.0 2.6e-48 165.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1619) Tenui_NS4 PF03300.13 GBG73605.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus non-structural, movement protein NS4 Ribosomal_L18A PF01775.17 GBG73606.1 - 7.6e-52 174.5 0.9 9.8e-52 174.2 0.9 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A LRR_9 PF14580.6 GBG73607.1 - 5.4e-14 52.1 0.3 9.4e-14 51.3 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 GBG73607.1 - 2.3e-11 43.7 30.1 2.9e-05 24.3 7.5 3.7 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG73607.1 - 2.4e-06 27.2 15.4 0.0037 17.0 2.2 3.8 1 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 GBG73607.1 - 0.091 12.9 8.1 2.7 8.3 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Cwf_Cwc_15 PF04889.12 GBG73607.1 - 0.18 11.5 4.5 0.39 10.4 4.5 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 GBG73607.1 - 0.5 8.4 4.8 0.7 7.9 4.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GBG73607.1 - 0.62 9.3 2.9 0.89 8.8 2.9 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GBG73607.1 - 0.77 10.2 11.4 1.9 8.9 11.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LRR_1 PF00560.33 GBG73607.1 - 3 8.7 8.4 39 5.4 3.0 4.3 3 1 1 4 4 4 0 Leucine Rich Repeat TFIIA PF03153.13 GBG73607.1 - 9 6.2 9.6 1.1 9.1 2.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RVP_2 PF08284.11 GBG73608.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73608.1 - 0.04 14.5 0.0 0.11 13.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG73608.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG73610.1 - 1.3e-27 96.6 0.1 2e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73610.1 - 5.1e-05 23.0 0.2 0.00013 21.7 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PALP PF00291.25 GBG73611.1 - 5.4e-54 183.6 1.4 6e-54 183.4 1.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RVT_1 PF00078.27 GBG73612.1 - 5.1e-23 81.8 0.0 1.7e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73612.1 - 3.6e-17 62.2 0.3 9.8e-17 60.8 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG73612.1 - 5.8e-14 52.2 0.0 1.2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG73612.1 - 1.1e-11 44.7 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 GBG73612.1 - 1.2e-08 34.9 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Plant_tran PF04827.14 GBG73612.1 - 0.00026 20.7 0.0 0.00079 19.1 0.0 1.7 2 0 0 2 2 2 1 Plant transposon protein SE PF08491.10 GBG73614.1 - 0.12 11.4 0.3 0.13 11.3 0.3 1.0 1 0 0 1 1 1 0 Squalene epoxidase SDA1 PF05285.12 GBG73615.1 - 0.054 12.9 47.5 0.067 12.6 47.5 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG73615.1 - 0.098 10.9 46.0 0.12 10.6 46.0 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG73615.1 - 3.1 7.1 41.9 3.5 6.9 41.9 1.1 1 0 0 1 1 1 0 BUD22 CCSAP PF15748.5 GBG73615.1 - 3.3 7.8 19.1 5 7.2 19.1 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 GBG73615.1 - 4.3 6.0 19.7 4.5 5.9 19.7 1.1 1 0 0 1 1 1 0 Presenilin CAF1 PF04857.20 GBG73615.1 - 8.1 5.5 6.4 13 4.8 6.4 1.5 1 1 0 1 1 1 0 CAF1 family ribonuclease Mpp10 PF04006.12 GBG73616.1 - 2.2 6.6 37.6 3 6.2 37.6 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG73616.1 - 2.9 6.0 40.4 3.4 5.8 40.4 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG73616.1 - 4.9 7.4 36.7 6.9 7.0 36.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Histone PF00125.24 GBG73617.1 - 9e-21 74.6 0.7 9e-21 74.6 0.7 3.9 3 1 1 4 4 4 1 Core histone H2A/H2B/H3/H4 zf-U11-48K PF05253.12 GBG73617.1 - 0.1 12.5 0.2 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger Raftlin PF15250.6 GBG73617.1 - 0.39 9.4 0.0 0.39 9.4 0.0 3.4 3 0 0 3 3 3 0 Raftlin Na_trans_assoc PF06512.13 GBG73618.1 - 0.0047 17.2 13.5 0.0059 16.9 13.5 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated Nop14 PF04147.12 GBG73618.1 - 0.0074 14.6 35.0 0.0084 14.4 35.0 1.2 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.15 GBG73618.1 - 0.19 10.4 10.6 0.18 10.5 10.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 GBG73618.1 - 3.4 7.7 5.3 5.3 7.0 5.3 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PALP PF00291.25 GBG73620.1 - 1e-56 192.5 0.4 1.6e-56 191.9 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CDC45 PF02724.14 GBG73620.1 - 0.87 7.8 32.5 1.2 7.3 32.5 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG73620.1 - 2.1 7.6 32.3 2.9 7.1 32.3 1.3 1 0 0 1 1 1 0 BUD22 Roughex PF06020.11 GBG73620.1 - 5.8 5.9 23.2 10 5.1 23.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Red1 PF07964.11 GBG73620.1 - 8.3 4.5 11.2 10 4.2 11.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Zip PF02535.22 GBG73620.1 - 9.7 5.3 8.7 15 4.7 8.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 GBG73622.1 - 0.36 10.1 17.0 0.46 9.8 17.0 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG73622.1 - 0.38 10.1 13.4 0.45 9.9 13.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG73622.1 - 2.5 6.3 12.2 3.5 5.8 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG73622.1 - 3.3 5.8 15.5 4.1 5.5 15.5 1.0 1 0 0 1 1 1 0 Nop14-like family La PF05383.17 GBG73623.1 - 6.3e-23 80.6 0.0 1.2e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 GBG73623.1 - 0.0018 18.1 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRCC PF10253.9 GBG73623.1 - 0.019 15.8 0.0 0.019 15.8 0.0 5.8 3 2 1 4 4 4 0 Mitotic checkpoint regulator, MAD2B-interacting GIY-YIG PF01541.24 GBG73624.1 - 1.4e-08 34.9 0.0 1.4e-08 34.9 0.0 3.9 4 1 0 4 4 4 1 GIY-YIG catalytic domain Alanine_zipper PF11839.8 GBG73624.1 - 0.055 13.8 21.4 0.15 12.5 21.4 1.7 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DUF3439 PF11921.8 GBG73624.1 - 0.82 9.6 2.9 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF3381 PF11861.8 GBG73624.1 - 9 6.1 30.2 0.083 12.7 12.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) RVT_1 PF00078.27 GBG73625.1 - 5.2e-27 94.8 0.1 1e-26 93.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73625.1 - 1.1e-16 60.7 0.3 2.6e-16 59.4 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG73625.1 - 3.7e-09 36.4 0.0 7.6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG73625.1 - 1.3e-07 31.8 0.0 3.8e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG73625.1 - 2.7e-07 31.1 0.0 6.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73625.1 - 1.4e-06 28.8 0.0 3.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG73625.1 - 0.00025 20.8 0.0 0.00069 19.5 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG73625.1 - 0.0029 17.4 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG73625.1 - 0.04 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase SlyX PF04102.12 GBG73625.1 - 0.052 14.2 0.2 0.052 14.2 0.2 3.8 4 0 0 4 4 2 0 SlyX DUF16 PF01519.16 GBG73625.1 - 0.053 14.0 0.3 0.51 10.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 Retrotrans_gag PF03732.17 GBG73625.1 - 0.079 13.2 0.0 0.32 11.3 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Chromo PF00385.24 GBG73625.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain tRNA-synt_2 PF00152.20 GBG73626.1 - 8.2e-62 209.1 0.0 1.2e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GBG73626.1 - 2.6e-09 36.9 1.2 1e-08 35.1 0.7 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Sigma70_r2 PF04542.14 GBG73626.1 - 0.031 14.1 0.1 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 Sigma-70 region 2 RT_RNaseH_2 PF17919.1 GBG73627.1 - 2e-20 72.7 0.0 4.7e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73627.1 - 3.3e-20 72.3 0.0 7e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG73627.1 - 5.4e-07 30.1 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73627.1 - 3.7e-05 24.3 0.0 8.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG73627.1 - 0.0034 17.2 0.3 0.0059 16.4 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG73627.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_5 PF14787.6 GBG73627.1 - 0.14 11.9 0.6 0.35 10.6 0.6 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger ILVD_EDD PF00920.21 GBG73628.1 - 1.1e-217 723.7 0.1 1.4e-217 723.5 0.1 1.1 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 GBG73628.1 - 0.017 15.4 0.0 0.07 13.4 0.0 2.1 1 0 0 1 1 1 0 FeoA domain PspA_IM30 PF04012.12 GBG73629.1 - 1.2e-45 155.8 16.9 1.8e-45 155.2 16.9 1.2 1 0 0 1 1 1 1 PspA/IM30 family HAP1_N PF04849.13 GBG73629.1 - 0.018 14.3 1.5 0.018 14.3 1.5 2.4 3 0 0 3 3 3 0 HAP1 N-terminal conserved region TMF_DNA_bd PF12329.8 GBG73629.1 - 0.019 14.9 12.2 0.17 11.9 3.8 3.3 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 GBG73629.1 - 0.12 12.5 7.7 0.27 11.3 4.0 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 GBG73629.1 - 0.12 12.5 4.6 0.6 10.3 4.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Leu_zip PF15294.6 GBG73629.1 - 0.55 9.7 10.1 0.81 9.1 3.9 2.1 1 1 0 2 2 2 0 Leucine zipper DUF4201 PF13870.6 GBG73629.1 - 0.82 9.4 10.3 9.3 5.9 6.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Muted PF14942.6 GBG73629.1 - 1.2 9.5 5.8 0.75 10.1 2.5 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Spc7 PF08317.11 GBG73629.1 - 1.2 8.0 14.4 0.073 11.9 8.9 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein CHDCT2 PF08074.11 GBG73629.1 - 2.1 8.5 8.1 0.3 11.2 0.2 2.8 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain DivIC PF04977.15 GBG73629.1 - 2.2 8.1 7.2 0.64 9.8 2.8 2.4 3 0 0 3 3 3 0 Septum formation initiator XhlA PF10779.9 GBG73629.1 - 2.3 8.5 5.2 28 5.0 1.2 2.6 2 0 0 2 2 2 0 Haemolysin XhlA CLZ PF16526.5 GBG73629.1 - 3 8.3 11.3 0.84 10.0 2.7 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4094 PF13334.6 GBG73629.1 - 4.1 7.9 6.5 2.1 8.8 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) SlyX PF04102.12 GBG73629.1 - 5.4 7.7 6.7 21 5.8 0.5 3.2 3 0 0 3 3 3 0 SlyX Csm1_N PF18504.1 GBG73629.1 - 6.5 7.2 7.7 16 6.0 2.4 3.1 3 0 0 3 3 3 0 Csm1 N-terminal domain DDE_Tnp_4 PF13359.6 GBG73630.1 - 6.9e-33 113.6 0.0 5.3e-32 110.7 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73630.1 - 4.3e-17 62.4 0.0 1.1e-16 61.0 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG73630.1 - 0.041 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Methyltransf_25 PF13649.6 GBG73632.1 - 3.6e-22 78.9 5.3 1.1e-20 74.2 0.1 3.2 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG73632.1 - 3.2e-21 75.7 0.0 5.3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GBG73632.1 - 4.9e-19 68.8 1.5 3.8e-18 65.9 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG73632.1 - 3.9e-14 52.7 1.5 5.9e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG73632.1 - 1.9e-11 44.5 0.4 1.2e-10 42.0 0.0 2.4 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.14 GBG73632.1 - 5.9e-06 25.9 0.4 2.4e-05 24.0 0.5 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 GBG73632.1 - 7.3e-06 25.4 0.1 1.2e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 GBG73632.1 - 2.1e-05 24.4 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 GBG73632.1 - 0.00057 19.1 0.0 0.0008 18.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.17 GBG73632.1 - 0.0042 16.6 0.0 0.0087 15.5 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 GBG73632.1 - 0.0065 16.1 0.0 0.0096 15.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 GBG73632.1 - 0.011 15.5 1.4 0.021 14.5 0.1 1.9 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_8 PF05148.15 GBG73632.1 - 0.03 14.2 0.0 0.03 14.2 0.0 1.7 2 1 0 2 2 1 0 Hypothetical methyltransferase Methyltransf_18 PF12847.7 GBG73632.1 - 0.046 13.6 0.1 0.072 13.0 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 GBG73632.1 - 0.09 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DsbD PF02683.15 GBG73633.1 - 4e-45 154.3 8.6 5.9e-45 153.8 8.6 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Isochorismatase PF00857.20 GBG73634.1 - 1e-31 110.4 0.0 1.3e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family HupH_C PF04809.13 GBG73634.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region RNase_PH PF01138.21 GBG73635.1 - 1.1e-20 74.4 0.2 1.8e-20 73.7 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF659 PF04937.15 GBG73636.1 - 9.4e-19 67.8 0.0 2.3e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73636.1 - 1.7e-05 24.5 0.1 3.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PI-PLC-X PF00388.19 GBG73637.1 - 0.024 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain RVT_1 PF00078.27 GBG73638.1 - 9.5e-31 107.0 0.1 1.4e-30 106.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.7 GBG73640.1 - 1.6e-16 60.7 0.2 1.4e-13 51.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG73640.1 - 3.6e-15 56.1 0.6 7.2e-11 42.4 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG73640.1 - 6.8e-15 55.0 0.3 1.4e-11 44.4 0.4 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG73640.1 - 5.4e-13 47.9 0.5 3.2e-05 24.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat PARP PF00644.20 GBG73640.1 - 3.4e-11 43.1 0.0 6.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ank PF00023.30 GBG73640.1 - 9.4e-10 38.5 2.6 0.00018 21.8 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat SDA1 PF05285.12 GBG73641.1 - 0.041 13.3 19.3 0.047 13.1 19.3 1.2 1 0 0 1 1 1 0 SDA1 Serinc PF03348.15 GBG73641.1 - 0.56 9.1 0.9 0.77 8.6 0.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Lin-8 PF03353.15 GBG73641.1 - 0.56 9.7 13.4 0.66 9.5 13.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 GBG73641.1 - 1.8 6.7 17.8 2.1 6.6 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG73641.1 - 2.3 6.3 24.0 2.7 6.1 24.0 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 GBG73641.1 - 6.9 5.8 4.7 7.1 5.7 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_C48 PF02902.19 GBG73642.1 - 1.2e-07 31.9 5.2 4.9e-07 29.8 5.2 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4820 PF16091.5 GBG73643.1 - 0.015 14.6 0.8 0.037 13.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Abhydrolase_1 PF00561.20 GBG73644.1 - 1.5e-22 80.5 0.1 1.1e-16 61.2 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG73644.1 - 6.2e-21 76.0 0.7 6.2e-21 76.0 0.7 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG73644.1 - 2.5e-07 30.2 0.0 5.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 MBOAT PF03062.19 GBG73646.1 - 4.4e-35 121.7 18.9 4.4e-35 121.7 18.9 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SelK_SelG PF10961.8 GBG73646.1 - 0.72 10.5 6.5 0.49 11.1 0.7 2.7 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Topo_Zn_Ribbon PF08272.11 GBG73647.1 - 0.023 14.4 0.3 0.047 13.3 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like PRP1_N PF06424.12 GBG73650.1 - 2.8e-56 190.0 2.8 6.1e-56 188.9 2.8 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 GBG73650.1 - 3.8e-32 108.2 37.1 1e-05 26.0 0.1 15.3 6 5 11 17 17 16 9 Tetratricopeptide repeat TPR_19 PF14559.6 GBG73650.1 - 3.6e-23 81.9 3.4 4.5e-05 23.9 0.1 8.5 6 2 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 GBG73650.1 - 9.2e-13 47.6 1.0 0.061 13.7 0.0 8.6 9 2 1 10 10 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG73650.1 - 2.5e-12 47.3 15.3 0.031 14.9 0.0 7.8 7 2 1 9 9 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG73650.1 - 6.3e-11 41.5 14.3 0.49 10.6 0.0 9.4 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG73650.1 - 1e-08 34.7 0.0 1.5 9.2 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 GBG73650.1 - 7.2e-06 26.2 0.0 0.14 12.1 0.0 4.3 3 1 2 5 5 5 1 Suppressor of forked protein (Suf) TPR_11 PF13414.6 GBG73650.1 - 7.5e-06 25.5 1.0 17 5.2 0.0 6.5 5 1 1 6 6 6 0 TPR repeat NARP1 PF12569.8 GBG73650.1 - 0.00022 20.3 0.2 1.5 7.6 0.0 3.9 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 GBG73650.1 - 0.00023 21.2 10.2 0.68 10.1 0.0 5.9 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 GBG73650.1 - 0.00053 19.3 19.9 0.2 10.8 1.7 6.1 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG73650.1 - 0.0012 18.6 1.0 2.2 8.2 0.0 5.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG73650.1 - 0.0036 17.5 10.6 14 6.1 0.0 7.1 8 1 1 9 9 8 0 Tetratricopeptide repeat Hen1_Lam_C PF18441.1 GBG73650.1 - 0.15 11.9 0.0 12 5.7 0.0 2.3 1 1 1 2 2 2 0 Hen1 La-motif C-terminal domain TetR_C_11 PF16859.5 GBG73650.1 - 0.39 11.1 3.6 1.4 9.3 0.3 3.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PMC2NT PF08066.12 GBG73650.1 - 0.46 11.2 1.9 0.48 11.2 0.0 2.0 2 0 0 2 2 1 0 PMC2NT (NUC016) domain TPR_21 PF09976.9 GBG73650.1 - 0.5 10.1 5.1 18 5.0 0.9 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain DUF465 PF04325.13 GBG73650.1 - 1 9.5 4.7 19 5.4 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) TPR_4 PF07721.14 GBG73650.1 - 1.3 9.8 0.0 1.3 9.8 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG73650.1 - 2.4 9.0 15.7 39 5.2 0.0 7.1 8 0 0 8 8 5 0 Tetratricopeptide repeat APG6_N PF17675.1 GBG73650.1 - 7.6 7.1 6.5 2.8 8.5 0.6 3.0 2 1 0 2 2 2 0 Apg6 coiled-coil region Acyltransferase PF01553.21 GBG73651.1 - 2.8e-17 62.6 0.0 1.2e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase p12I PF12233.8 GBG73651.1 - 0.29 11.6 3.1 2.6 8.6 0.3 2.3 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein RT_RNaseH_2 PF17919.1 GBG73653.1 - 5.2e-23 81.0 0.0 8.6e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73653.1 - 6e-20 71.5 0.0 1.2e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73653.1 - 7.6e-14 51.7 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG73654.1 - 0.47 10.6 6.1 0.068 13.3 1.9 1.8 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L3 PF00297.22 GBG73655.1 - 1.4e-180 600.2 6.3 1.5e-180 600.0 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Cytochrom_B562 PF07361.11 GBG73655.1 - 0.044 14.5 0.2 1.2 9.9 0.0 2.4 2 0 0 2 2 2 0 Cytochrome b562 DUF3671 PF12420.8 GBG73655.1 - 0.062 13.4 2.4 0.13 12.4 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function IMS_HHH PF11798.8 GBG73655.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif Dimer_Tnp_hAT PF05699.14 GBG73656.1 - 0.00034 20.3 0.1 0.0063 16.3 0.0 2.5 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Pox_Ag35 PF03286.14 GBG73656.1 - 0.13 12.0 2.9 0.24 11.2 2.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 GBG73657.1 - 0.77 7.9 29.1 0.93 7.6 29.1 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-N PF05238.13 GBG73657.1 - 2.1 7.5 8.5 2.7 7.2 8.5 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Retrotrans_gag PF03732.17 GBG73658.1 - 0.14 12.4 0.5 0.55 10.6 0.2 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein Ribosomal_L4 PF00573.22 GBG73658.1 - 2.4 7.8 5.7 1.8 8.2 3.6 1.8 2 0 0 2 2 2 0 Ribosomal protein L4/L1 family gag-asp_proteas PF13975.6 GBG73659.1 - 7.8e-07 29.6 0.1 1.6e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73659.1 - 4e-05 24.2 0.1 8.8e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG73659.1 - 0.00028 20.7 0.1 0.00051 19.8 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73659.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG73659.1 - 0.41 10.8 1.9 0.99 9.6 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG73660.1 - 1.6e-12 47.3 0.1 4.7e-12 45.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG73660.1 - 9.7e-10 38.3 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73660.1 - 2.3e-05 24.5 0.0 5.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG73660.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG73661.1 - 2.2e-06 28.1 0.0 6.4e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73661.1 - 8.5e-06 26.3 0.0 2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG73661.1 - 3.2e-05 24.1 4.1 0.00019 21.6 0.1 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG73661.1 - 8.5e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73661.1 - 0.00017 21.4 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG73661.1 - 0.0078 15.7 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG73662.1 - 3.4e-05 24.3 0.1 0.00018 22.0 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG73662.1 - 3.7e-05 23.9 1.9 0.00028 21.1 0.2 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG73662.1 - 5.9e-05 23.6 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73662.1 - 0.00012 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73662.1 - 0.0016 18.2 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG73662.1 - 0.017 14.6 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG73663.1 - 4e-07 30.6 0.0 7.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73663.1 - 1.5e-06 28.7 0.0 2.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG73663.1 - 0.00023 20.9 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73663.1 - 0.00024 20.9 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG73663.1 - 0.0033 17.0 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG73664.1 - 5.1e-28 98.1 0.1 9e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73664.1 - 3.7e-27 94.3 0.0 1.8e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73664.1 - 1.4e-25 89.6 0.0 3e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73664.1 - 2.1e-07 30.9 0.2 5.5e-07 29.6 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF3106 PF11304.8 GBG73665.1 - 0.5 10.9 4.9 0.099 13.1 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) rve PF00665.26 GBG73667.1 - 5.6e-12 45.9 0.0 1.4e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG73667.1 - 1.1e-11 44.7 0.5 2.3e-11 43.6 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-C2H2_10 PF16588.5 GBG73668.1 - 0.061 13.1 3.5 0.12 12.1 3.5 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 GBG73668.1 - 0.15 11.8 0.7 0.33 10.7 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle DinB_2 PF12867.7 GBG73668.1 - 0.2 12.2 1.7 17 5.9 0.1 2.2 2 0 0 2 2 2 0 DinB superfamily zf-CCHC_2 PF13696.6 GBG73668.1 - 3.7 7.5 5.5 5.3 7.0 5.5 1.2 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L3 PF00297.22 GBG73669.1 - 1.6e-121 405.8 4.0 2e-121 405.4 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3671 PF12420.8 GBG73669.1 - 0.071 13.2 2.4 0.13 12.4 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function IMS_HHH PF11798.8 GBG73669.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Ribosomal_L3 PF00297.22 GBG73670.1 - 6e-136 453.3 3.2 6.8e-136 453.1 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3671 PF12420.8 GBG73670.1 - 0.029 14.4 1.8 0.058 13.5 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function IMS_HHH PF11798.8 GBG73670.1 - 0.093 13.1 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif PseudoU_synth_1 PF01416.20 GBG73671.1 - 7.2e-15 55.4 0.0 3.4e-12 46.8 0.0 2.8 2 0 0 2 2 2 2 tRNA pseudouridine synthase DDE_Tnp_4 PF13359.6 GBG73672.1 - 1.9e-18 66.7 0.0 7.3e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73672.1 - 1.5e-08 34.5 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG73672.1 - 0.083 13.3 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG73673.1 - 0.076 13.4 0.0 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DBD_Tnp_Mut PF03108.15 GBG73674.1 - 9.9e-17 60.7 0.3 2e-16 59.7 0.3 1.5 1 0 0 1 1 1 1 MuDR family transposase Jnk-SapK_ap_N PF09744.9 GBG73676.1 - 0.15 12.3 6.4 0.065 13.5 3.6 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Csm1_N PF18504.1 GBG73676.1 - 0.39 11.1 2.2 0.8 10.1 0.9 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain TPR_MLP1_2 PF07926.12 GBG73676.1 - 6.4 6.9 9.8 3.6 7.7 7.3 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Dimer_Tnp_hAT PF05699.14 GBG73677.1 - 0.0068 16.2 2.6 0.079 12.8 2.6 2.0 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region DUF5314 PF17241.2 GBG73677.1 - 0.08 12.6 0.1 0.09 12.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Asp_protease_2 PF13650.6 GBG73679.1 - 6.8e-07 29.9 0.0 5e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73679.1 - 0.00017 22.0 0.0 0.00044 20.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF659 PF04937.15 GBG73680.1 - 3.3e-29 101.7 0.4 3.6e-28 98.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG73683.1 - 3.9e-31 108.3 0.1 6.6e-31 107.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73683.1 - 7.3e-18 64.5 0.0 1.4e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG73683.1 - 3.8e-06 27.4 0.0 1.3e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG73683.1 - 1.3e-05 25.4 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG73683.1 - 3e-05 23.8 0.0 5.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG73683.1 - 0.00031 20.6 0.1 0.0019 18.0 0.0 2.0 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG73683.1 - 0.00053 20.6 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG73684.1 - 0.044 14.0 0.1 0.044 14.0 0.1 4.3 5 1 0 5 5 5 0 Retrotransposon gag protein Colicin_E5 PF12106.8 GBG73684.1 - 0.092 13.1 0.1 0.33 11.3 0.1 2.0 1 0 0 1 1 1 0 Colicin E5 ribonuclease domain CRR7 PF12095.8 GBG73684.1 - 2.7 8.5 7.3 12 6.5 1.5 3.8 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF3450 PF11932.8 GBG73686.1 - 0.1 11.9 23.6 0.2 10.9 1.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) RRP36 PF06102.12 GBG73686.1 - 0.34 10.9 15.3 0.079 12.9 6.4 2.3 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Aconitase PF00330.20 GBG73686.1 - 0.39 9.7 2.7 0.22 10.5 0.4 1.6 2 0 0 2 2 2 0 Aconitase family (aconitate hydratase) DUF4140 PF13600.6 GBG73686.1 - 0.49 10.9 12.6 2.3 8.7 6.0 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 GBG73686.1 - 0.5 9.7 11.5 3.2 7.0 5.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fungal_trans_2 PF11951.8 GBG73686.1 - 0.56 9.0 3.3 0.89 8.3 3.3 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain ISG65-75 PF11727.8 GBG73686.1 - 0.93 8.7 13.0 0.045 13.0 7.6 1.5 2 0 0 2 2 2 0 Invariant surface glycoprotein OmpH PF03938.14 GBG73686.1 - 1.1 9.5 19.6 0.24 11.7 11.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) YabA PF06156.13 GBG73686.1 - 2.3 8.9 14.4 5.6 7.7 7.6 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 GBG73686.1 - 3 7.3 8.1 0.92 9.0 2.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4164 PF13747.6 GBG73686.1 - 3.2 8.1 13.5 9.9 6.5 4.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF3552 PF12072.8 GBG73686.1 - 3.6 7.0 23.8 0.95 8.8 11.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) APG6_N PF17675.1 GBG73686.1 - 4.3 7.9 25.7 1.8 9.1 12.4 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 GBG73686.1 - 9.5 6.4 21.2 1.4 9.1 2.7 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 RT_RNaseH_2 PF17919.1 GBG73687.1 - 7e-35 119.1 0.3 2.5e-21 75.6 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73687.1 - 8.4e-31 106.4 1.5 7.2e-19 68.0 1.6 2.7 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73687.1 - 1.7e-19 69.6 0.1 3.4e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73687.1 - 1.4e-15 57.5 0.0 5.3e-15 55.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG73687.1 - 0.03 14.5 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Sporozoite_P67 PF05642.11 GBG73688.1 - 0.0016 16.6 9.7 0.0022 16.2 9.7 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CDC45 PF02724.14 GBG73688.1 - 0.095 11.0 31.8 0.0093 14.3 21.5 2.0 2 0 0 2 2 2 0 CDC45-like protein eIF-3c_N PF05470.12 GBG73688.1 - 0.46 8.7 18.0 0.44 8.8 15.8 1.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.13 GBG73688.1 - 1.4 8.7 31.3 2.4 8.0 1.9 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 GBG73688.1 - 2.7 6.0 30.7 0.14 10.2 24.7 1.7 2 0 0 2 2 2 0 DNA polymerase phi Astro_capsid_p PF12226.8 GBG73688.1 - 4.3 6.4 15.4 7.5 5.6 15.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DDHD PF02862.17 GBG73688.1 - 5.9 7.0 9.4 7 6.7 3.4 2.2 2 0 0 2 2 2 0 DDHD domain CENP-Q PF13094.6 GBG73689.1 - 0.0073 16.5 5.7 0.0073 16.5 5.7 2.3 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Filament PF00038.21 GBG73689.1 - 0.085 12.4 8.2 3.5 7.1 0.2 3.1 2 1 0 3 3 3 0 Intermediate filament protein Sod_Fe_C PF02777.18 GBG73690.1 - 5.7e-37 126.0 0.5 1.5e-36 124.6 0.2 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GBG73690.1 - 4.1e-32 110.5 0.9 6.8e-32 109.8 0.9 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF5617 PF18493.1 GBG73690.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) Ribosomal_60s PF00428.19 GBG73691.1 - 0.024 15.2 6.1 0.024 15.2 6.1 3.1 2 1 1 3 3 3 0 60s Acidic ribosomal protein Zip PF02535.22 GBG73691.1 - 0.16 11.1 1.9 0.17 11.1 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 GBG73691.1 - 0.21 9.8 15.4 0.25 9.6 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 GBG73691.1 - 1 8.9 22.2 1.6 8.2 22.2 1.3 1 0 0 1 1 1 0 PPP4R2 PNISR PF15996.5 GBG73691.1 - 1.6 9.0 17.4 1.9 8.7 17.4 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SAPS PF04499.15 GBG73691.1 - 2.8 6.6 6.5 3.1 6.5 6.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_polI_A34 PF08208.11 GBG73691.1 - 8 6.5 17.8 11 6.1 17.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Gly_transf_sug PF04488.15 GBG73692.1 - 2.1e-18 66.8 0.0 3.8e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 GBG73692.1 - 6.6e-15 55.4 0.2 1e-14 54.8 0.2 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region NAD_binding_7 PF13241.6 GBG73692.1 - 0.2 12.1 0.0 0.47 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Alpha-amyl_C2 PF07821.12 GBG73693.1 - 1e-20 73.7 0.0 2.5e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 GBG73693.1 - 1.9e-16 60.6 0.0 1.2e-15 57.9 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 GBG73693.1 - 0.064 11.4 0.0 0.12 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 Rhodanese PF00581.20 GBG73696.1 - 1.2e-24 86.9 0.0 1.8e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain TFIIE-A_C PF11521.8 GBG73697.1 - 0.48 10.7 5.5 7.1 7.0 2.2 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha RAP80_UIM PF18282.1 GBG73697.1 - 8.6 6.2 10.8 3 7.7 0.3 2.1 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif FERM_F1 PF18379.1 GBG73698.1 - 0.11 12.6 0.0 14 5.8 0.0 2.3 2 0 0 2 2 2 0 FERM F1 ubiquitin-like domain DUF588 PF04535.12 GBG73699.1 - 0.00081 19.2 0.5 0.0012 18.6 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF588) KleE PF17394.2 GBG73699.1 - 0.031 14.5 1.4 0.071 13.3 0.4 1.9 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein Claudin_2 PF13903.6 GBG73699.1 - 0.073 12.8 2.2 0.12 12.1 2.2 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Wzy_C PF04932.15 GBG73699.1 - 0.53 9.9 2.8 0.76 9.4 2.7 1.3 1 1 0 1 1 1 0 O-Antigen ligase DUF588 PF04535.12 GBG73702.1 - 0.0011 18.7 6.5 0.0016 18.2 6.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF588) MARVEL PF01284.23 GBG73702.1 - 1.2 9.2 12.3 2 8.4 12.3 1.3 1 0 0 1 1 1 0 Membrane-associating domain RVT_1 PF00078.27 GBG73704.1 - 1.6e-25 89.9 0.7 2.2e-25 89.5 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73704.1 - 1.5e-23 82.7 0.0 6.2e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73704.1 - 4.3e-20 72.0 0.0 7.5e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG73704.1 - 0.026 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 RVT_1 PF00078.27 GBG73705.1 - 6.2e-28 97.8 0.1 1.1e-27 97.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73705.1 - 1.8e-26 92.5 0.0 4.1e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73705.1 - 4.1e-26 90.9 0.0 4.4e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase CRCB PF02537.15 GBG73707.1 - 0.058 13.7 0.2 0.28 11.5 0.1 2.1 1 1 1 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) Utp14 PF04615.13 GBG73707.1 - 0.33 9.5 15.5 0.49 8.9 15.5 1.3 1 0 0 1 1 1 0 Utp14 protein Nop14 PF04147.12 GBG73707.1 - 5.5 5.1 21.7 7.1 4.7 21.7 1.0 1 0 0 1 1 1 0 Nop14-like family UFD1 PF03152.14 GBG73709.1 - 1.5e-78 262.2 0.0 1.9e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Period_C PF12114.8 GBG73709.1 - 1 8.9 3.9 1.7 8.2 3.9 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Cwf_Cwc_15 PF04889.12 GBG73709.1 - 7.9 6.1 26.3 0.84 9.3 21.1 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 GBG73709.1 - 8.1 6.9 19.4 18 5.7 19.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal POPLD PF08170.12 GBG73711.1 - 0.00064 20.0 0.7 0.00064 20.0 0.7 1.9 2 0 0 2 2 2 1 POPLD (NUC188) domain POP1 PF06978.11 GBG73711.1 - 0.0014 18.6 0.9 0.0042 17.1 0.9 1.8 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 Auts2 PF15336.6 GBG73711.1 - 0.15 12.1 8.8 0.083 13.0 5.8 2.1 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein DUF3915 PF13054.6 GBG73711.1 - 1.3 9.1 5.4 2.9 7.9 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF4294 PF14127.6 GBG73712.1 - 0.31 11.0 4.4 1.6 8.6 4.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4294) Radial_spoke_3 PF06098.11 GBG73713.1 - 2.8e-98 328.7 9.6 2.8e-98 328.7 9.6 4.2 2 1 1 4 4 4 1 Radial spoke protein 3 DUF2258 PF10015.9 GBG73713.1 - 0.00053 20.1 21.2 1.4 9.1 0.3 6.1 6 0 0 6 6 6 4 Uncharacterized protein conserved in archaea (DUF2258) Dimerisation2 PF16864.5 GBG73713.1 - 1.1 9.2 5.6 33 4.5 0.1 4.3 4 0 0 4 4 4 0 Dimerisation domain AA_kinase PF00696.28 GBG73713.1 - 1.2 8.7 8.1 0.77 9.3 1.8 3.3 3 1 0 3 3 3 0 Amino acid kinase family CN_hydrolase PF00795.22 GBG73714.1 - 2.3e-50 171.4 0.2 1.8e-43 148.8 0.0 2.2 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase Sulfate_transp PF00916.20 GBG73715.1 - 2.2e-111 372.3 14.3 2.8e-111 371.9 14.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GBG73715.1 - 1.5e-22 79.5 0.0 2.7e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GBG73715.1 - 3.3e-05 24.2 7.2 3.3e-05 24.2 7.2 2.6 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 GBG73715.1 - 0.05 13.9 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 STAS domain DUF659 PF04937.15 GBG73716.1 - 2.3e-27 95.7 0.0 3.9e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73716.1 - 6.8e-05 22.6 0.3 0.00014 21.6 0.3 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SDA1 PF05285.12 GBG73716.1 - 0.093 12.1 15.3 0.16 11.4 15.3 1.4 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 GBG73716.1 - 0.2 11.6 4.4 0.39 10.6 4.4 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 GBG73716.1 - 0.22 10.8 11.5 0.61 9.4 11.5 1.7 1 0 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.12 GBG73716.1 - 0.53 10.1 3.8 0.93 9.3 3.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 GBG73716.1 - 1.1 7.4 14.6 1.6 6.9 14.6 1.2 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.12 GBG73716.1 - 1.3 7.9 13.2 2 7.3 13.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Myc_N PF01056.18 GBG73716.1 - 1.6 8.5 7.7 5.4 6.8 7.4 1.8 2 0 0 2 2 2 0 Myc amino-terminal region Astro_capsid_p PF12226.8 GBG73716.1 - 2.9 7.0 7.5 4.6 6.3 7.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PPP4R2 PF09184.11 GBG73716.1 - 4.9 6.7 12.2 8.8 5.8 12.2 1.4 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 GBG73716.1 - 9.7 4.3 15.5 14 3.8 15.5 1.2 1 0 0 1 1 1 0 CDC45-like protein gag-asp_proteas PF13975.6 GBG73717.1 - 5.7e-05 23.6 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73717.1 - 0.00041 20.1 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG73717.1 - 0.0006 20.4 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG73717.1 - 0.067 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Presenilin PF01080.17 GBG73718.1 - 0.39 9.4 0.9 0.34 9.6 0.9 1.0 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 GBG73718.1 - 3.8 5.3 3.9 3.9 5.3 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 GBG73718.1 - 5.1 6.8 4.5 5.5 6.7 4.5 1.1 1 0 0 1 1 1 0 Connexin RVT_1 PF00078.27 GBG73722.1 - 7.7e-28 97.5 0.1 1.2e-27 96.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73722.1 - 3.3e-12 46.3 0.0 8.5e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73722.1 - 9.4e-05 22.7 0.0 0.00028 21.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG73722.1 - 0.0099 16.1 0.1 0.037 14.3 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG73722.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease MICSWaP PF17018.5 GBG73722.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Spore wall protein Glyco_transf_29 PF00777.18 GBG73723.1 - 5.9e-14 52.1 0.3 4.8e-13 49.1 0.3 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) EGF_Tenascin PF18720.1 GBG73723.1 - 0.00055 19.9 13.7 0.001 19.0 13.7 1.5 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 GBG73723.1 - 0.0023 18.3 11.7 0.0045 17.3 11.7 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 GBG73723.1 - 0.1 13.3 5.5 0.21 12.3 5.5 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF Glyco_transf_29 PF00777.18 GBG73724.1 - 3.7e-14 52.8 0.2 3.3e-13 49.7 0.2 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) RT_RNaseH_2 PF17919.1 GBG73725.1 - 1.1e-31 108.8 0.0 1.4e-16 60.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73725.1 - 4.3e-30 104.1 0.0 8.7e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73725.1 - 1.6e-27 96.5 0.1 2.8e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73725.1 - 9e-14 51.3 0.0 1.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73725.1 - 0.047 13.9 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVT_3 PF13456.6 GBG73725.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like EMC3_TMCO1 PF01956.16 GBG73726.1 - 0.00065 19.5 0.4 0.00065 19.5 0.4 2.0 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like DUF1676 PF07898.13 GBG73726.1 - 0.0079 16.3 1.2 0.0079 16.3 1.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1676) TMEM220 PF15071.6 GBG73726.1 - 0.0094 16.7 1.8 0.02 15.6 1.8 1.5 1 0 0 1 1 1 1 Transmembrane family 220, helix CENP-B_dimeris PF09026.10 GBG73726.1 - 0.01 16.2 17.5 0.01 16.2 17.5 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain ZapB PF06005.12 GBG73726.1 - 0.035 14.6 0.2 0.035 14.6 0.2 2.6 2 0 0 2 2 2 0 Cell division protein ZapB 7tm_1 PF00001.21 GBG73726.1 - 0.043 13.1 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Peptidase_S8 PF00082.22 GBG73726.1 - 0.054 12.7 0.5 0.12 11.7 0.5 1.6 1 0 0 1 1 1 0 Subtilase family HAUS5 PF14817.6 GBG73726.1 - 0.55 8.9 10.2 0.59 8.8 4.5 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 5 Spc7 PF08317.11 GBG73726.1 - 2 7.2 11.6 1.4 7.8 0.4 2.9 2 1 0 2 2 2 0 Spc7 kinetochore protein Cellulase PF00150.18 GBG73727.1 - 1.5e-11 44.3 0.0 2.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 GBG73728.1 - 1.7e-09 37.5 0.0 2.4e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DDE_Tnp_4 PF13359.6 GBG73730.1 - 8.4e-32 110.0 0.0 1.4e-31 109.3 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73730.1 - 2.9e-12 46.6 0.0 4.4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG73730.1 - 0.096 12.3 0.1 14 5.3 0.1 2.4 2 1 0 2 2 2 0 Transposase DDE domain RVT_1 PF00078.27 GBG73732.1 - 5.7e-29 101.2 0.1 9.3e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73732.1 - 3.7e-18 65.4 0.0 9.6e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73732.1 - 8.1e-07 29.3 0.0 2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73734.1 - 2.1e-31 107.9 0.0 6.3e-31 106.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73734.1 - 4.2e-31 107.4 0.1 8.2e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG73734.1 - 0.0017 18.6 0.1 0.0077 16.5 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Phage_GPO PF05929.11 GBG73734.1 - 0.078 12.6 0.1 0.078 12.6 0.1 2.5 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_lysozyme PF00959.19 GBG73734.1 - 0.11 12.9 0.1 0.92 10.0 0.0 2.6 3 0 0 3 3 3 0 Phage lysozyme Aminotran_5 PF00266.19 GBG73735.1 - 4.6e-92 308.8 0.0 1e-91 307.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GBG73735.1 - 9.5e-09 34.9 0.4 2.4e-08 33.6 0.1 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GBG73735.1 - 4.5e-05 22.9 0.0 8.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 GBG73735.1 - 5.8e-05 22.0 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain NIPSNAP PF07978.13 GBG73735.1 - 0.044 14.0 0.1 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 NIPSNAP Retrotrans_gag PF03732.17 GBG73739.1 - 0.0029 17.8 0.4 0.033 14.5 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein RasGEF_N PF00618.20 GBG73739.1 - 0.09 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 RasGEF N-terminal motif Prominin PF05478.11 GBG73739.1 - 4.7 5.0 7.5 6.7 4.5 7.5 1.2 1 0 0 1 1 1 0 Prominin RVT_1 PF00078.27 GBG73740.1 - 9.2e-25 87.5 1.6 3.2e-24 85.7 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73740.1 - 5.8e-20 71.2 0.0 1.8e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73740.1 - 5.3e-19 68.4 0.0 1.5e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG73740.1 - 2.9e-05 24.2 0.6 0.0033 17.6 0.0 3.1 2 0 0 2 2 2 1 Retrotransposon gag protein Aminotran_5 PF00266.19 GBG73742.1 - 2.9e-92 309.5 0.0 3.5e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GBG73742.1 - 1.3e-08 34.4 0.1 2e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 GBG73742.1 - 4.7e-05 22.3 0.0 9.5e-05 21.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 GBG73742.1 - 5.9e-05 22.5 0.0 9.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family NIPSNAP PF07978.13 GBG73742.1 - 0.014 15.6 0.1 0.082 13.1 0.0 2.1 2 0 0 2 2 2 0 NIPSNAP Cys_Met_Meta_PP PF01053.20 GBG73742.1 - 0.18 10.3 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme UPF0172 PF03665.13 GBG73743.1 - 3.9e-10 40.1 0.0 4.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) CYTH PF01928.21 GBG73744.1 - 2.8e-26 92.5 0.1 3.4e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 CYTH domain LMBR1 PF04791.16 GBG73745.1 - 0.21 10.5 2.7 0.3 9.9 2.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 GBG73745.1 - 0.48 9.1 11.2 0.81 8.4 11.2 1.3 1 1 0 1 1 1 0 Presenilin AAA_23 PF13476.6 GBG73745.1 - 5 7.6 21.1 5.7 7.4 0.3 2.1 2 0 0 2 2 2 0 AAA domain EF-hand_1 PF00036.32 GBG73746.1 - 2.6e-32 107.9 15.0 5.7e-08 31.8 0.2 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 GBG73746.1 - 5.3e-31 106.9 11.3 3.2e-16 59.5 1.9 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG73746.1 - 1.9e-26 89.7 10.4 2.4e-08 33.3 0.2 5.0 3 1 2 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 GBG73746.1 - 9.3e-21 73.4 13.9 3.6e-10 39.5 1.3 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GBG73746.1 - 2.7e-20 70.9 21.1 4.5e-07 29.1 0.3 5.5 6 0 0 6 6 5 4 EF hand EF-hand_9 PF14658.6 GBG73746.1 - 1.8e-10 41.0 1.5 1.7e-05 25.0 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GBG73746.1 - 4.6e-06 26.9 1.0 0.014 15.7 0.1 3.1 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GBG73746.1 - 0.00066 19.6 3.0 0.35 10.9 0.3 2.5 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 GBG73746.1 - 0.0014 18.5 0.9 0.46 10.4 0.0 3.1 2 2 1 3 3 3 1 Caleosin related protein RapH_N PF18801.1 GBG73746.1 - 0.014 15.5 0.1 0.36 10.9 0.0 2.5 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal DUF2666 PF10869.8 GBG73746.1 - 0.066 13.4 0.4 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) EF-hand_14 PF17959.1 GBG73746.1 - 0.17 12.2 0.2 7.2 7.0 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain p25-alpha PF05517.12 GBG73746.1 - 1.3 9.1 6.9 29 4.8 0.1 3.3 3 0 0 3 3 3 0 p25-alpha PPR_2 PF13041.6 GBG73747.1 - 1.6e-05 25.0 0.0 5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 GBG73747.1 - 0.031 14.5 0.4 0.43 10.9 0.0 3.2 4 0 0 4 4 4 0 PPR repeat B12-binding PF02310.19 GBG73748.1 - 2.8e-16 59.6 0.5 4.6e-16 59.0 0.5 1.3 1 0 0 1 1 1 1 B12 binding domain MM_CoA_mutase PF01642.22 GBG73749.1 - 6.9e-160 533.0 1.9 1.7e-138 462.4 0.1 2.1 1 1 1 2 2 2 2 Methylmalonyl-CoA mutase RT_RNaseH_2 PF17919.1 GBG73749.1 - 4.3e-32 110.1 0.0 9.3e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73749.1 - 4.2e-28 97.7 0.2 7.7e-28 96.9 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG73749.1 - 4e-07 30.5 0.0 1.7e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73749.1 - 0.0004 21.0 0.0 0.0012 19.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG73749.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG73749.1 - 0.067 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease PhnI PF05861.12 GBG73749.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) DUF393 PF04134.12 GBG73750.1 - 3.5e-21 76.7 0.1 6.3e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF393 ABC_membrane PF00664.23 GBG73751.1 - 7.2e-107 357.1 20.7 3.8e-60 203.9 6.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GBG73751.1 - 1.3e-70 236.2 0.0 2.9e-34 118.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GBG73751.1 - 1.3e-13 50.9 2.6 0.00017 21.1 0.0 4.3 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GBG73751.1 - 5.6e-08 33.4 0.3 0.0093 16.4 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 GBG73751.1 - 1e-06 27.9 0.8 0.0031 16.4 0.1 2.8 2 1 1 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 GBG73751.1 - 2.1e-06 27.4 0.1 0.06 13.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG73751.1 - 1e-05 25.8 0.3 0.072 13.4 0.0 3.5 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GBG73751.1 - 2e-05 24.5 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 GBG73751.1 - 2.2e-05 23.9 0.1 0.05 12.9 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin AAA_15 PF13175.6 GBG73751.1 - 2.5e-05 24.2 0.0 0.054 13.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GBG73751.1 - 3.3e-05 23.9 0.1 1.3 8.8 0.0 4.1 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 GBG73751.1 - 0.00096 19.2 0.5 6.6 6.7 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 GBG73751.1 - 0.0027 17.9 5.7 1.7 8.9 0.4 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 GBG73751.1 - 0.0055 16.5 3.9 2.2 8.0 0.4 3.5 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.17 GBG73751.1 - 0.0064 16.6 0.1 0.53 10.3 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain TetR_C_14 PF17754.1 GBG73751.1 - 0.017 15.0 0.0 2.8 7.9 0.0 3.1 3 0 0 3 3 2 0 MftR C-terminal domain APS_kinase PF01583.20 GBG73751.1 - 0.022 14.7 0.2 0.55 10.1 0.1 2.8 3 0 0 3 3 3 0 Adenylylsulphate kinase DUF815 PF05673.13 GBG73751.1 - 0.027 13.7 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_PrkA PF08298.11 GBG73751.1 - 0.035 13.0 0.1 0.68 8.8 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain AAA_25 PF13481.6 GBG73751.1 - 0.047 13.3 0.1 1.7 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 GBG73751.1 - 0.059 13.1 0.0 9 6.0 0.0 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 GBG73751.1 - 0.11 13.0 0.0 20 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GBG73751.1 - 0.12 11.9 0.0 8.6 5.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 GBG73751.1 - 0.14 11.3 0.0 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit CLP_protease PF00574.23 GBG73752.1 - 4.6e-69 231.9 0.1 6.8e-69 231.4 0.1 1.2 1 0 0 1 1 1 1 Clp protease GTP_EFTU PF00009.27 GBG73753.1 - 1.2e-68 230.5 0.0 1.7e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GBG73753.1 - 3.2e-46 156.0 0.1 6.9e-46 155.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 GBG73753.1 - 4.4e-33 113.2 0.1 1e-32 112.0 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GBG73753.1 - 7.9e-25 86.7 0.0 2.7e-24 85.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GBG73753.1 - 2.5e-14 53.4 0.1 6.6e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GBG73753.1 - 7.3e-07 29.1 0.1 1.5e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GBG73753.1 - 0.002 18.2 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GBG73753.1 - 0.0087 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF659 PF04937.15 GBG73754.1 - 1.4e-26 93.2 0.0 2.7e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG73755.1 - 3.4e-09 37.0 1.6 7.2e-09 35.9 0.5 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG73755.1 - 0.045 14.1 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG73756.1 - 1.6e-20 73.4 0.0 2.4e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73756.1 - 1.6e-07 31.2 0.0 2.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein UQ_con PF00179.26 GBG73757.1 - 5.1e-27 94.2 0.0 5.4e-21 74.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme tRNA_anti-codon PF01336.25 GBG73758.1 - 3.1e-07 30.3 0.3 5.3e-07 29.5 0.3 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 GBG73758.1 - 1.6e-05 24.8 0.1 2.5e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 RPA_C PF08784.11 GBG73758.1 - 3.4e-05 24.5 0.6 8.1e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 Replication protein A C terminal BOF PF04076.13 GBG73758.1 - 0.029 14.4 0.6 0.029 14.4 0.6 1.9 2 0 0 2 2 2 0 Bacterial OB fold (BOF) protein ABC_membrane PF00664.23 GBG73759.1 - 4.7e-107 357.7 23.0 2.3e-56 191.5 9.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GBG73759.1 - 7.7e-72 240.2 0.0 1.2e-34 119.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GBG73759.1 - 3.5e-14 52.8 5.6 0.00079 18.9 0.0 4.3 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GBG73759.1 - 1.9e-08 34.9 3.7 0.0008 19.8 0.2 3.2 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 GBG73759.1 - 2.8e-07 29.7 1.5 0.0057 15.5 0.1 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 GBG73759.1 - 6.8e-07 28.9 0.1 0.051 13.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GBG73759.1 - 3.8e-06 26.3 0.2 0.097 11.9 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin AAA_15 PF13175.6 GBG73759.1 - 5e-06 26.5 0.0 0.055 13.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GBG73759.1 - 1.2e-05 25.6 0.6 0.061 13.6 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GBG73759.1 - 2.1e-05 24.5 0.7 1.1 9.0 0.1 3.9 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GBG73759.1 - 3.1e-05 23.9 0.1 0.26 11.2 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 GBG73759.1 - 4.8e-05 23.1 1.5 0.037 13.7 0.1 3.1 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 GBG73759.1 - 0.00011 22.1 0.4 0.94 9.5 0.0 3.8 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 GBG73759.1 - 0.00014 22.3 0.6 2.1 8.8 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 GBG73759.1 - 0.00038 19.7 0.1 0.65 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) DUF87 PF01935.17 GBG73759.1 - 0.00078 19.6 0.3 1.9 8.5 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_7 PF12775.7 GBG73759.1 - 0.0016 18.0 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 GBG73759.1 - 0.0017 18.1 0.0 0.38 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GBG73759.1 - 0.0025 18.1 0.0 19 5.5 0.0 4.3 4 1 0 4 4 3 0 AAA domain AAA_25 PF13481.6 GBG73759.1 - 0.0057 16.2 0.3 0.33 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 GBG73759.1 - 0.0066 15.7 0.0 0.87 8.7 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_18 PF13238.6 GBG73759.1 - 0.0068 17.0 0.0 4.5 7.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 GBG73759.1 - 0.011 15.6 0.0 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 GBG73759.1 - 0.015 15.5 0.1 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 GBG73759.1 - 0.023 14.9 6.8 0.91 9.8 0.6 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Cytidylate_kin PF02224.18 GBG73759.1 - 0.026 14.2 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase PRK PF00485.18 GBG73759.1 - 0.04 13.7 0.1 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 GBG73759.1 - 0.048 13.3 0.0 2 8.0 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain KAP_NTPase PF07693.14 GBG73759.1 - 0.085 12.1 0.0 7.1 5.8 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain Roc PF08477.13 GBG73759.1 - 0.1 12.8 0.1 18 5.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GBG73759.1 - 0.12 12.5 0.8 16 5.6 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 GBG73759.1 - 0.19 11.6 0.0 21 5.0 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_23 PF13476.6 GBG73759.1 - 0.22 12.0 0.0 9.3 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain FumaraseC_C PF10415.9 GBG73759.1 - 0.25 11.8 1.6 0.6 10.6 0.2 2.3 2 0 0 2 2 1 0 Fumarase C C-terminus Dynamin_N PF00350.23 GBG73759.1 - 0.32 11.1 1.4 23 5.0 0.1 2.7 2 0 0 2 2 2 0 Dynamin family Glutaredoxin PF00462.24 GBG73760.1 - 3.1e-09 36.9 0.0 9.7e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 Glutaredoxin KH_7 PF17214.3 GBG73760.1 - 0.05 13.6 0.3 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 KH domain RVT_1 PF00078.27 GBG73761.1 - 1.7e-13 50.6 0.0 4.1e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GLTT PF01744.20 GBG73762.1 - 1.1e-12 47.3 5.2 2.5e-07 30.2 1.1 4.0 2 1 2 4 4 4 3 GLTT repeat (6 copies) CDC45 PF02724.14 GBG73763.1 - 7e-05 21.3 4.0 0.00014 20.3 3.6 1.7 2 0 0 2 2 2 1 CDC45-like protein DUF1676 PF07898.13 GBG73763.1 - 0.00029 20.9 3.1 0.0006 19.9 3.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) Cwf_Cwc_15 PF04889.12 GBG73763.1 - 0.0024 17.6 14.2 0.0044 16.8 14.2 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Pes-10 PF07149.11 GBG73763.1 - 0.0066 15.6 6.1 0.0093 15.1 6.1 1.1 1 0 0 1 1 1 1 Pes-10 NOA36 PF06524.12 GBG73763.1 - 0.017 14.5 17.9 0.028 13.8 17.9 1.2 1 0 0 1 1 1 0 NOA36 protein Orf78 PF06024.12 GBG73763.1 - 0.021 15.1 0.2 0.046 14.0 0.2 1.5 1 0 0 1 1 1 0 Orf78 (ac78) GCIP PF13324.6 GBG73763.1 - 0.03 13.9 5.2 0.063 12.9 5.2 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PBP1_TM PF14812.6 GBG73763.1 - 0.051 13.9 30.0 0.38 11.2 30.0 2.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 GBG73763.1 - 0.13 12.3 6.5 0.33 11.0 6.5 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal CNDH2_C PF16858.5 GBG73763.1 - 0.14 12.0 4.0 0.21 11.4 4.0 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Sigma70_ner PF04546.13 GBG73763.1 - 0.15 11.9 5.8 0.27 11.1 5.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 GBG73763.1 - 0.15 10.6 11.5 0.25 9.9 11.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Utp14 PF04615.13 GBG73763.1 - 0.18 10.3 8.7 0.23 10.0 8.7 1.1 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 GBG73763.1 - 0.21 10.9 4.6 0.31 10.3 4.6 1.2 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 GBG73763.1 - 0.26 11.5 14.8 0.5 10.6 14.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SKN1 PF03935.15 GBG73763.1 - 0.36 9.2 4.3 0.54 8.6 4.3 1.2 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) YL1 PF05764.13 GBG73763.1 - 0.52 10.4 14.6 1 9.4 14.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein PPP4R2 PF09184.11 GBG73763.1 - 0.62 9.6 7.6 0.98 9.0 7.6 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 GBG73763.1 - 0.64 9.4 10.3 1.2 8.4 10.3 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG73763.1 - 0.96 7.6 9.7 1.3 7.1 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family Lig_chan PF00060.26 GBG73763.1 - 0.97 9.3 3.3 2.8 7.8 3.3 1.7 1 0 0 1 1 1 0 Ligand-gated ion channel DUF2457 PF10446.9 GBG73763.1 - 1.4 7.9 24.6 2.4 7.2 24.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SURF2 PF05477.11 GBG73763.1 - 2.3 7.8 6.6 3.6 7.2 6.6 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DNA_pol_phi PF04931.13 GBG73763.1 - 3.1 5.8 19.2 4.6 5.2 19.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 GBG73763.1 - 6 5.3 12.7 11 4.5 12.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spt5_N PF11942.8 GBG73763.1 - 7.3 7.6 21.2 8.7 7.4 19.6 1.9 2 0 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal zf-CCHC PF00098.23 GBG73765.1 - 5.9e-05 23.0 6.4 0.00012 22.0 6.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Hamartin PF04388.12 GBG73765.1 - 0.0017 17.2 0.6 0.002 16.9 0.6 1.0 1 0 0 1 1 1 1 Hamartin protein DDRGK PF09756.9 GBG73765.1 - 0.13 11.8 14.5 0.18 11.4 14.5 1.2 1 0 0 1 1 1 0 DDRGK domain PRKG1_interact PF15898.5 GBG73765.1 - 1 10.3 11.6 3.3 8.7 8.0 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF659 PF04937.15 GBG73766.1 - 6.2e-20 71.6 0.0 9.2e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG73766.1 - 0.11 12.7 0.0 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain Integrase_H2C2 PF17921.1 GBG73768.1 - 1.1e-06 28.6 0.3 2.1e-06 27.8 0.3 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73768.1 - 0.0035 17.5 0.0 0.0064 16.7 0.0 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Na_trans_assoc PF06512.13 GBG73768.1 - 0.54 10.5 9.7 0.68 10.2 9.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG73768.1 - 0.73 9.2 18.9 0.94 8.8 18.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG73768.1 - 7.5 4.6 19.4 9.4 4.3 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG73769.1 - 4.3e-32 111.4 0.0 6.5e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-binding PF00249.31 GBG73770.1 - 3e-06 27.3 11.8 0.00054 20.1 2.3 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG73770.1 - 4.7e-06 26.8 4.9 1.1e-05 25.6 3.5 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 GBG73770.1 - 0.19 11.9 0.8 0.69 10.0 0.0 2.3 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_6 PF13921.6 GBG73771.1 - 4.1e-07 30.1 1.3 1.2e-06 28.7 1.3 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG73771.1 - 1.3e-06 28.5 9.1 0.00027 21.0 2.1 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain CDC45 PF02724.14 GBG73771.1 - 1.6e-05 23.5 6.5 1.6e-05 23.5 6.5 1.1 1 0 0 1 1 1 1 CDC45-like protein PTPRCAP PF15713.5 GBG73771.1 - 0.024 14.9 26.6 0.054 13.8 26.6 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GBG73771.1 - 0.042 12.1 18.8 0.052 11.8 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family Rap1_C PF11626.8 GBG73771.1 - 0.1 12.7 0.0 0.1 12.7 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain CPSF100_C PF13299.6 GBG73771.1 - 0.18 12.0 5.9 0.27 11.4 5.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 GBG73771.1 - 0.55 9.6 3.1 0.6 9.5 3.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SDA1 PF05285.12 GBG73771.1 - 0.62 9.4 22.7 0.88 8.9 22.7 1.1 1 0 0 1 1 1 0 SDA1 MDM1 PF15501.6 GBG73771.1 - 1.2 8.2 15.5 1.6 7.8 15.5 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 DUF2052 PF09747.9 GBG73771.1 - 6.2 6.9 25.8 4.2 7.5 23.8 1.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Mpp10 PF04006.12 GBG73771.1 - 6.8 5.0 26.3 9.1 4.6 26.3 1.0 1 0 0 1 1 1 0 Mpp10 protein Presenilin PF01080.17 GBG73771.1 - 8.4 5.0 10.7 11 4.6 10.7 1.1 1 0 0 1 1 1 0 Presenilin Merozoite_SPAM PF07133.11 GBG73771.1 - 9.8 6.1 39.4 14 5.6 39.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) S-AdoMet_synt_C PF02773.16 GBG73774.1 - 7.2e-65 217.1 0.6 1.9e-64 215.8 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GBG73774.1 - 9.6e-49 164.6 0.0 1.8e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG73774.1 - 2.7e-43 146.7 0.2 7.9e-43 145.2 0.2 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DnaJ_CXXCXGXG PF00684.19 GBG73774.1 - 0.28 11.6 3.6 0.59 10.5 3.6 1.5 1 0 0 1 1 1 0 DnaJ central domain PHD PF00628.29 GBG73774.1 - 2.1 8.3 4.4 6.4 6.8 0.1 2.3 2 0 0 2 2 2 0 PHD-finger RT_RNaseH_2 PF17919.1 GBG73775.1 - 3.1e-10 40.0 0.0 7.4e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73775.1 - 4.6e-09 36.5 0.0 2.1e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73775.1 - 1.5e-07 31.2 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG73775.1 - 4.4e-06 27.2 0.1 1e-05 26.0 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73775.1 - 4.8e-05 23.9 0.1 0.00012 22.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG73775.1 - 0.0011 18.7 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG73775.1 - 0.75 10.0 1.9 1.5 9.0 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Glucosamine_iso PF01182.20 GBG73776.1 - 7e-77 258.3 0.0 9.4e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HSP70 PF00012.20 GBG73777.1 - 3.1e-257 854.6 3.7 3.5e-257 854.4 3.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG73777.1 - 1.2e-15 57.2 0.2 9e-15 54.3 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG73777.1 - 1.3e-05 25.1 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 GBG73777.1 - 0.0026 16.8 0.4 0.2 10.6 0.2 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 GBG73777.1 - 0.029 14.8 1.7 33 5.0 0.0 3.6 3 1 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 GBG73777.1 - 0.042 13.1 0.3 0.25 10.6 0.1 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Radial_spoke_3 PF06098.11 GBG73777.1 - 0.048 12.9 5.0 0.1 11.9 5.0 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 DUF1464 PF07318.12 GBG73777.1 - 0.049 12.8 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) TBCA PF02970.16 GBG73777.1 - 8.8 6.7 13.2 3.6 8.0 8.2 2.4 2 0 0 2 2 2 0 Tubulin binding cofactor A MaoC_dehydratas PF01575.19 GBG73778.1 - 5.5e-23 80.9 0.1 7.3e-23 80.5 0.1 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GBG73778.1 - 0.001 19.2 0.0 0.0044 17.1 0.0 2.1 1 1 1 2 2 2 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 GBG73778.1 - 0.1 12.9 0.1 0.29 11.5 0.1 1.9 1 1 0 1 1 1 0 Thioesterase superfamily Sucrose_synth PF00862.19 GBG73779.1 - 1.4e-253 842.2 0.0 1.7e-253 842.0 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG73779.1 - 6.8e-28 97.3 0.0 1.3e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG73779.1 - 4.4e-10 40.1 0.0 1.1e-09 38.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG73779.1 - 0.00018 21.8 0.0 0.00053 20.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG73779.1 - 0.0011 18.9 0.1 0.081 12.9 0.1 3.0 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Pox_D5 PF03288.16 GBG73779.1 - 0.084 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like Adaptin_binding PF10199.9 GBG73780.1 - 0.047 14.3 3.5 0.15 12.7 3.5 1.7 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 GAS PF13851.6 GBG73780.1 - 0.3 10.4 15.3 1.3 8.3 2.0 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2681 PF10883.8 GBG73780.1 - 1.4 9.4 5.9 0.64 10.5 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF3496 PF12001.8 GBG73780.1 - 1.7 9.0 8.6 0.085 13.2 1.9 2.2 2 2 0 2 2 2 0 Domain of unknown function (DUF3496) Prefoldin_2 PF01920.20 GBG73780.1 - 5.3 7.1 13.3 3.7 7.5 5.7 2.7 2 1 0 2 2 2 0 Prefoldin subunit DUF5082 PF16888.5 GBG73780.1 - 7.7 6.8 9.5 1.7 8.9 0.3 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) Sucrose_synth PF00862.19 GBG73781.1 - 1.4e-253 842.2 0.0 1.7e-253 842.0 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG73781.1 - 1e-27 96.8 0.0 1.9e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG73781.1 - 7.4e-10 39.4 0.0 1.8e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG73781.1 - 0.00018 21.8 0.0 0.00053 20.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG73781.1 - 0.0012 18.9 0.1 0.081 12.9 0.1 2.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Pox_D5 PF03288.16 GBG73781.1 - 0.084 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like LPP PF04728.13 GBG73782.1 - 0.099 13.0 10.1 0.28 11.6 0.3 3.5 4 1 0 4 4 4 0 Lipoprotein leucine-zipper FliD_N PF02465.18 GBG73782.1 - 3.3 8.4 6.3 4.2 8.1 2.2 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Fzo_mitofusin PF04799.13 GBG73782.1 - 7.1 6.1 12.6 3.1 7.3 0.7 2.9 2 1 1 3 3 3 0 fzo-like conserved region TP53IP5 PF15331.6 GBG73783.1 - 1.1 9.3 13.0 1.7 8.7 13.0 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF5401 PF17380.2 GBG73783.1 - 3.3 5.6 24.3 4.5 5.2 24.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Sucrose_synth PF00862.19 GBG73784.1 - 2.4e-252 838.1 0.0 2.9e-252 837.9 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG73784.1 - 2.4e-27 95.6 0.0 4.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG73784.1 - 1.3e-09 38.6 0.0 3.3e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG73784.1 - 0.00017 21.9 0.0 0.00053 20.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG73784.1 - 0.0012 18.9 0.1 0.081 12.9 0.1 2.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Pox_D5 PF03288.16 GBG73784.1 - 0.085 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like PspA_IM30 PF04012.12 GBG73786.1 - 0.0011 18.6 10.8 0.0011 18.6 10.8 2.0 3 0 0 3 3 3 1 PspA/IM30 family Halo_GVPC PF05465.13 GBG73786.1 - 0.0087 16.3 0.6 0.019 15.2 0.6 1.5 1 0 0 1 1 1 1 Halobacterial gas vesicle protein C (GVPC) repeat PRIMA1 PF16101.5 GBG73786.1 - 4.6 7.3 12.0 9.4 6.3 12.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DivIC PF04977.15 GBG73786.1 - 4.9 7.0 6.4 3.3 7.6 0.5 3.0 3 0 0 3 3 3 0 Septum formation initiator Ran-binding PF05508.11 GBG73786.1 - 5.1 6.0 6.6 2 7.3 0.2 2.3 2 1 1 3 3 3 0 RanGTP-binding protein HSP70 PF00012.20 GBG73787.1 - 5.9e-94 315.4 0.0 1e-91 308.0 0.0 2.8 2 1 0 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG73787.1 - 7.8e-18 64.7 0.0 9e-12 44.9 0.0 3.2 2 1 0 2 2 2 2 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG73787.1 - 9.4e-07 27.9 0.7 0.00054 18.9 0.7 3.4 3 1 0 3 3 3 2 MreB/Mbl protein Sin_N PF04801.13 GBG73787.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Fib_alpha PF08702.10 GBG73788.1 - 0.38 10.9 4.7 0.57 10.4 4.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FAM178 PF14816.6 GBG73788.1 - 1.1 8.1 3.3 1.8 7.5 3.3 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF1943 PF09172.11 GBG73788.1 - 1.8 7.8 7.8 2.3 7.4 7.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) HSP70 PF00012.20 GBG73789.1 - 6.3e-33 113.8 0.0 9e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein TIM PF00121.18 GBG73789.1 - 5.2e-16 58.8 0.0 6.4e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 Triosephosphate isomerase Nop14 PF04147.12 GBG73790.1 - 1.8 6.7 19.1 3 5.9 19.1 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4519 PF15012.6 GBG73791.1 - 0.066 13.4 1.3 0.12 12.5 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) RelE PF06296.12 GBG73792.1 - 0.0046 17.1 0.3 0.011 15.9 0.3 1.5 1 0 0 1 1 1 1 RelE toxin of RelE / RelB toxin-antitoxin system HSP70 PF00012.20 GBG73794.1 - 7.4e-96 321.7 0.0 9.1e-69 232.2 0.2 2.1 2 0 0 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG73794.1 - 1.6e-22 80.1 0.0 2.1e-08 33.9 0.0 3.3 3 0 0 3 3 3 3 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG73794.1 - 7e-10 38.2 1.3 0.00064 18.6 0.4 3.3 3 0 0 3 3 3 2 MreB/Mbl protein DEC-1_N PF04625.13 GBG73794.1 - 8.2 5.3 7.3 14 4.6 7.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region HSP70 PF00012.20 GBG73795.1 - 4e-36 124.4 0.0 6.1e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein TIM PF00121.18 GBG73795.1 - 1.1e-16 61.0 0.0 1.6e-14 53.9 0.0 2.6 1 1 1 2 2 2 2 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG73795.1 - 0.061 12.1 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 MreB/Mbl protein gag-asp_proteas PF13975.6 GBG73796.1 - 1.5e-06 28.7 0.1 3.1e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73796.1 - 4e-05 24.2 0.1 9.6e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG73796.1 - 0.0013 18.5 0.1 0.0022 17.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73796.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG73796.1 - 0.063 13.4 1.9 0.14 12.3 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle HSP70 PF00012.20 GBG73797.1 - 6.3e-148 493.6 0.2 1.4e-121 406.6 0.1 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG73797.1 - 8.8e-14 51.1 1.0 4e-12 45.6 0.5 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG73797.1 - 2.2e-06 27.5 0.1 8.4e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain RT_RNaseH_2 PF17919.1 GBG73798.1 - 1.3e-35 121.4 0.0 2.1e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73798.1 - 3.9e-22 78.5 0.0 6.9e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73798.1 - 3.7e-14 52.8 0.1 5.1e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF16 PF01519.16 GBG73799.1 - 0.046 14.2 18.0 0.53 10.8 7.7 4.7 2 1 1 3 3 3 0 Protein of unknown function DUF16 EzrA PF06160.12 GBG73799.1 - 0.068 11.3 25.2 0.055 11.6 11.5 3.2 2 1 2 4 4 4 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 GBG73799.1 - 0.1 12.8 20.1 0.17 12.1 6.7 3.6 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.17 GBG73799.1 - 0.59 10.1 15.4 2.1 8.3 0.1 4.3 2 1 1 3 3 3 0 Prefoldin subunit Cauli_AT PF03233.13 GBG73799.1 - 0.7 9.8 10.0 5 7.0 5.1 3.1 3 1 0 3 3 3 0 Aphid transmission protein Baculo_p24 PF05073.12 GBG73799.1 - 0.8 9.5 4.8 0.35 10.6 2.0 1.9 2 0 0 2 2 2 0 Baculovirus P24 capsid protein NPV_P10 PF05531.12 GBG73799.1 - 1.7 9.2 8.2 4.3 7.9 0.4 4.5 4 2 2 6 6 6 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.25 GBG73799.1 - 2.1 8.0 25.7 0.045 13.4 7.9 4.2 2 1 1 4 4 4 0 Syntaxin Tweety PF04906.13 GBG73799.1 - 5.2 5.6 7.2 1.3 7.6 0.2 2.5 2 1 1 3 3 3 0 Tweety DUF5595 PF18077.1 GBG73799.1 - 6.2 7.0 9.6 1.9 8.6 3.2 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) PIN_2 PF10130.9 GBG73799.1 - 8.7 6.6 8.9 0.9 9.8 3.5 2.2 2 0 0 2 2 2 0 PIN domain GIDE PF12483.8 GBG73800.1 - 5.8e-21 74.5 0.0 1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.6 GBG73800.1 - 8.5e-10 38.3 17.1 1.2e-09 37.8 17.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2062 PF09835.9 GBG73800.1 - 0.085 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) zf-RING_5 PF14634.6 GBG73800.1 - 0.99 9.4 18.1 1.6 8.8 18.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG73800.1 - 1.1 9.2 18.3 1.6 8.6 18.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG73800.1 - 1.6 8.7 16.3 2.6 8.0 16.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FA_hydroxylase PF04116.13 GBG73803.1 - 1.6e-19 70.6 20.3 1.6e-19 70.6 20.3 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SPC25 PF06703.11 GBG73803.1 - 0.47 10.2 2.2 0.55 10.0 0.7 1.9 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3522 PF12036.8 GBG73804.1 - 8.9e-13 48.9 2.4 1.7e-12 48.0 2.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3522) Phage_holin_3_6 PF07332.11 GBG73804.1 - 0.035 14.1 9.4 0.11 12.6 0.5 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2244 PF10003.9 GBG73804.1 - 0.64 9.7 4.0 3.4 7.4 0.5 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4131 PF13567.6 GBG73804.1 - 0.65 9.6 7.9 0.14 11.8 4.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) IRK PF01007.20 GBG73804.1 - 2.4 8.0 7.1 1.3 8.8 0.0 2.8 1 1 1 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF2207 PF09972.9 GBG73804.1 - 9 4.9 9.2 0.62 8.8 1.1 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) RVT_1 PF00078.27 GBG73805.1 - 4.2e-31 108.2 0.1 7.4e-31 107.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73805.1 - 6.1e-10 39.3 0.1 1.8e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain BLOC1_2 PF10046.9 GBG73805.1 - 0.0073 16.6 0.2 1.9 8.8 0.1 2.9 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_BLRF2 PF05812.12 GBG73805.1 - 0.036 14.2 1.2 0.059 13.5 0.2 1.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Retrotrans_gag PF03732.17 GBG73805.1 - 0.11 12.8 0.2 1.4 9.3 0.1 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein Med3 PF11593.8 GBG73805.1 - 0.8 8.8 9.5 0.19 10.9 5.3 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF3522 PF12036.8 GBG73806.1 - 1.1e-12 48.7 0.1 1.8e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) zf-RanBP PF00641.18 GBG73807.1 - 1.6e-15 56.1 19.4 1.4e-08 33.9 4.8 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 GBG73807.1 - 4.1e-08 32.9 0.0 3.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 GBG73808.1 - 1.6e-15 56.1 19.4 1.4e-08 33.9 4.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 GBG73808.1 - 1.1e-08 34.7 0.0 3.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L4 PF00573.22 GBG73811.1 - 6.6e-58 195.6 1.1 6.6e-58 195.6 1.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family CS PF04969.16 GBG73812.1 - 5.7e-17 62.5 0.0 1.2e-16 61.5 0.0 1.6 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 GBG73812.1 - 0.0014 18.6 0.9 0.0027 17.6 0.9 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Pox_Ag35 PF03286.14 GBG73813.1 - 1.2 8.9 6.4 0.47 10.2 0.4 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.6 GBG73813.1 - 1.4 8.5 7.1 0.23 11.1 0.3 2.3 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.6 GBG73813.1 - 3.9 7.8 12.9 6 7.1 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Ribosomal_60s PF00428.19 GBG73813.1 - 4.7 7.9 10.9 0.7 10.5 6.1 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4602 PF15375.6 GBG73816.1 - 0.0031 17.8 15.2 0.0031 17.8 15.2 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4602) DUF4577 PF15145.6 GBG73816.1 - 0.023 14.7 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF1838 PF08894.11 GBG73817.1 - 0.00036 20.3 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) RT_RNaseH_2 PF17919.1 GBG73818.1 - 9.4e-33 112.2 0.1 2.4e-32 111.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73818.1 - 1.5e-28 99.8 0.1 2.8e-28 99.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73818.1 - 2e-20 73.0 0.0 5.1e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG73818.1 - 0.14 11.9 0.0 0.48 10.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) DUF5095 PF17016.5 GBG73818.1 - 0.15 11.8 0.3 0.27 10.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Sortilin-Vps10 PF15902.5 GBG73819.1 - 5.9e-77 259.3 0.2 8.8e-77 258.8 0.2 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 GBG73819.1 - 2e-25 90.1 2.3 6.9e-25 88.4 0.8 2.2 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, C-terminal BNR_6 PF15899.5 GBG73819.1 - 0.009 16.0 0.1 0.45 10.7 0.0 3.6 2 0 0 2 2 2 1 BNR-Asp box repeat BNR PF02012.20 GBG73819.1 - 0.014 15.3 14.5 7.5 7.0 0.1 6.2 7 0 0 7 7 7 0 BNR/Asp-box repeat gpUL132 PF11359.8 GBG73820.1 - 0.071 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 Arc_PepC_II PF06847.11 GBG73820.1 - 4.2 7.9 8.7 6.2 7.4 0.5 3.5 2 1 1 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II RVT_1 PF00078.27 GBG73821.1 - 1.5e-09 37.7 0.0 3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG73821.1 - 6.1e-05 22.5 49.3 6.1e-05 22.5 49.3 7.3 4 1 1 5 5 5 2 BUD22 Lactamase_B_2 PF12706.7 GBG73821.1 - 0.017 14.7 0.4 0.034 13.7 0.4 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Myb_DNA-bind_4 PF13837.6 GBG73822.1 - 8.9e-06 26.0 2.1 1.4e-05 25.4 2.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG73823.1 - 1.1e-34 118.4 0.0 4.2e-34 116.6 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73823.1 - 1.6e-30 105.5 0.0 6.4e-30 103.5 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73823.1 - 2.4e-30 105.7 0.0 4.8e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73823.1 - 1.2e-17 63.7 0.2 2.8e-17 62.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73823.1 - 8.7e-11 42.1 0.1 5.2e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain SMC_hinge PF06470.13 GBG73823.1 - 3.4e-10 40.2 0.0 8.5e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 GBG73823.1 - 5.3e-09 35.8 0.1 2.5e-08 33.6 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GBG73823.1 - 1.7e-06 28.0 0.8 1.7e-06 28.0 0.8 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 GBG73823.1 - 0.12 12.1 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 GBG73823.1 - 0.15 11.8 0.0 0.59 9.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GBG73823.1 - 0.48 10.7 6.9 3.3 8.0 0.0 3.7 4 0 0 4 4 4 0 AAA domain Baculo_PEP_C PF04513.12 GBG73823.1 - 2.3 8.3 9.4 12 5.9 1.1 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF262 PF03235.14 GBG73824.1 - 4.8e-27 95.6 0.8 5e-26 92.2 0.8 2.2 1 1 0 1 1 1 1 Protein of unknown function DUF262 RVT_1 PF00078.27 GBG73825.1 - 1.5e-10 41.0 0.2 2.2e-10 40.4 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG73825.1 - 0.67 8.1 15.9 0.82 7.8 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG73825.1 - 1.1 8.6 15.1 1.3 8.3 15.1 1.2 1 0 0 1 1 1 0 SDA1 Pes-10 PF07149.11 GBG73825.1 - 4 6.4 9.0 5.3 6.0 9.0 1.2 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 GBG73825.1 - 5.4 5.2 13.4 7.4 4.7 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 GBG73825.1 - 6.1 5.8 8.6 8.2 5.4 8.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_C48 PF02902.19 GBG73826.1 - 8.4e-25 87.9 0.0 1.6e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RT_RNaseH PF17917.1 GBG73827.1 - 8.7e-12 45.3 0.0 1.5e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73827.1 - 0.0038 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG73827.1 - 0.15 11.4 8.9 0.23 10.9 8.9 1.2 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 GBG73827.1 - 0.27 11.5 12.4 0.59 10.4 12.4 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GBG73827.1 - 0.9 7.7 11.9 1.1 7.4 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG73827.1 - 3 6.0 10.6 3.7 5.7 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C48 PF02902.19 GBG73828.1 - 0.0003 20.7 0.0 0.00068 19.5 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF659 PF04937.15 GBG73830.1 - 1.8e-30 105.8 0.0 3.4e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG73830.1 - 2.4e-29 102.4 0.1 5e-29 101.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73830.1 - 2.6e-25 88.4 0.0 6.2e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73830.1 - 1.1e-24 86.7 0.0 1.9e-23 82.8 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73830.1 - 4.3e-14 52.4 0.1 1.4e-13 50.7 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Meckelin PF09773.9 GBG73830.1 - 1.3e-13 50.0 0.1 2e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Asp_protease_2 PF13650.6 GBG73830.1 - 0.00017 22.1 0.0 0.00044 20.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73830.1 - 0.00022 21.7 0.0 0.00058 20.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG73830.1 - 0.00053 19.8 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73830.1 - 0.00088 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Meckelin PF09773.9 GBG73831.1 - 2e-43 148.6 1.0 2e-43 148.6 1.0 1.5 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) DUF4618 PF15397.6 GBG73831.1 - 0.0018 17.7 0.5 0.0031 17.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) FlxA PF14282.6 GBG73831.1 - 0.0055 16.7 2.1 0.5 10.4 0.8 2.4 2 0 0 2 2 2 1 FlxA-like protein BLOC1_2 PF10046.9 GBG73831.1 - 0.024 14.9 1.6 0.37 11.1 0.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GBG73831.1 - 0.082 13.4 2.5 0.49 10.9 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_3 PF07726.11 GBG73831.1 - 0.12 12.2 0.1 47 3.8 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DivIC PF04977.15 GBG73831.1 - 0.39 10.5 3.3 1.3 8.9 1.5 2.3 2 0 0 2 2 2 0 Septum formation initiator HIP1_clath_bdg PF16515.5 GBG73831.1 - 0.39 11.4 10.0 0.082 13.5 1.6 2.7 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LPP PF04728.13 GBG73831.1 - 0.87 10.0 3.9 7.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper WXG100 PF06013.12 GBG73831.1 - 1.6 9.0 5.9 2.4 8.5 0.2 2.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG CLZ PF16526.5 GBG73831.1 - 1.9 8.9 4.0 11 6.4 2.3 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RT_RNaseH PF17917.1 GBG73832.1 - 1.4e-23 83.2 0.0 2.8e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73832.1 - 5.1e-22 77.8 0.0 1.1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73832.1 - 8.6e-14 51.4 0.4 2.2e-13 50.1 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG73832.1 - 1.3e-07 32.1 0.1 5.1e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG73832.1 - 4.3e-07 29.7 0.0 7.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG73832.1 - 0.00023 21.8 0.0 0.00071 20.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG73832.1 - 0.00037 20.4 9.5 0.048 13.8 1.2 2.8 2 0 0 2 2 2 2 Zinc knuckle Asp_protease PF09668.10 GBG73832.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG73832.1 - 0.051 13.8 0.7 0.12 12.6 0.7 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Meckelin PF09773.9 GBG73833.1 - 7.9e-50 169.8 0.0 1e-49 169.4 0.0 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Rad60-SLD PF11976.8 GBG73834.1 - 4.9e-09 35.9 0.0 7.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Meckelin PF09773.9 GBG73835.1 - 3.1e-09 35.6 0.7 3.3e-09 35.5 0.7 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) DUF1943 PF09172.11 GBG73836.1 - 0.51 9.5 11.5 0.66 9.1 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF2058 PF09831.9 GBG73836.1 - 1.6 8.9 18.0 3.4 7.8 18.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF2828 PF11443.8 GBG73836.1 - 4.3 5.3 13.2 5.5 5.0 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FHIPEP PF00771.20 GBG73836.1 - 5.4 5.3 5.8 6.9 5.0 5.8 1.1 1 0 0 1 1 1 0 FHIPEP family DUF659 PF04937.15 GBG73838.1 - 1.3e-26 93.2 0.0 2.3e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PAT1 PF09770.9 GBG73838.1 - 0.2 9.9 20.0 0.28 9.4 20.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 GBG73838.1 - 1.8 9.2 15.0 3.5 8.3 15.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 GBG73838.1 - 8.6 6.4 13.2 15 5.7 13.2 1.3 1 0 0 1 1 1 0 DDHD domain Lin-8 PF03353.15 GBG73838.1 - 9.9 5.6 27.7 17 4.8 27.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sporozoite_P67 PF05642.11 GBG73839.1 - 0.17 9.9 4.2 0.22 9.6 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Paf1 PF03985.13 GBG73839.1 - 0.18 10.8 8.1 0.26 10.3 8.1 1.2 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.6 GBG73839.1 - 0.35 10.5 6.0 0.63 9.7 6.0 1.4 1 0 0 1 1 1 0 FAM176 family NPR3 PF03666.13 GBG73839.1 - 1.6 7.5 4.7 1.7 7.4 4.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 GBG73839.1 - 1.6 6.8 10.2 2 6.4 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4746 PF15928.5 GBG73839.1 - 4 6.8 7.0 5.3 6.4 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 GBG73839.1 - 4.6 5.4 9.6 5.9 5.1 9.6 1.2 1 1 0 1 1 1 0 CDC45-like protein Dehydrin PF00257.19 GBG73839.1 - 8.1 7.0 17.5 0.39 11.3 10.3 2.2 1 1 1 2 2 2 0 Dehydrin DUF4407 PF14362.6 GBG73839.1 - 8.1 5.7 10.1 23 4.2 10.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2052 PF09747.9 GBG73839.1 - 10 6.2 14.9 12 6.0 14.9 1.3 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Not3 PF04065.15 GBG73840.1 - 1.1e-82 277.0 20.6 1.6e-82 276.4 20.6 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 GBG73840.1 - 3.3e-40 137.2 6.6 3.3e-40 137.2 6.6 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 GBG73840.1 - 2.8 8.3 7.4 0.34 11.3 2.2 2.1 2 0 0 2 2 2 0 Syntaxin-like protein MULE PF10551.9 GBG73841.1 - 3.1e-18 66.0 0.0 5.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 GBG73841.1 - 5.2e-05 22.3 0.0 8.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family CDC45 PF02724.14 GBG73841.1 - 0.082 11.2 3.6 0.11 10.7 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 GBG73841.1 - 1.8 8.3 9.3 3.4 7.4 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RVT_1 PF00078.27 GBG73842.1 - 1.7e-28 99.6 0.0 2.9e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73842.1 - 0.021 15.0 0.0 0.066 13.4 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 GBG73844.1 - 2.9e-07 30.9 0.0 8.3e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73844.1 - 4.7e-05 23.9 0.0 0.00012 22.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73844.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG73844.1 - 0.0093 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease cNMP_binding PF00027.29 GBG73844.1 - 0.13 12.3 0.3 1.2 9.3 0.0 2.5 3 0 0 3 3 3 0 Cyclic nucleotide-binding domain Pectinesterase PF01095.19 GBG73845.1 - 1.2e-79 267.1 0.5 2.1e-79 266.3 0.5 1.4 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.15 GBG73845.1 - 2.8e-07 31.0 3.0 5.1e-07 30.2 3.0 1.5 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor RT_RNaseH_2 PF17919.1 GBG73846.1 - 8e-35 118.9 0.0 1.3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73846.1 - 2.4e-31 108.1 0.0 5.7e-31 106.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73846.1 - 1.2e-06 28.2 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pectinesterase PF01095.19 GBG73849.1 - 8.8e-80 267.6 0.2 1.8e-79 266.6 0.2 1.5 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.15 GBG73849.1 - 3.8e-05 24.1 6.4 3.8e-05 24.1 6.4 1.6 2 0 0 2 2 2 1 Plant invertase/pectin methylesterase inhibitor DUF4140 PF13600.6 GBG73849.1 - 0.17 12.4 1.6 2 8.9 0.0 3.3 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) ERM PF00769.19 GBG73850.1 - 0.0003 20.7 5.7 0.0006 19.7 5.7 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Amastin PF07344.11 GBG73851.1 - 1.1 9.2 3.9 1.3 8.8 3.9 1.3 1 1 0 1 1 1 0 Amastin surface glycoprotein Nop14 PF04147.12 GBG73853.1 - 0.57 8.3 8.9 0.6 8.3 8.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG73853.1 - 1.3 7.3 8.4 1.5 7.1 8.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Malic_M PF03949.15 GBG73855.1 - 3.4e-86 288.7 0.3 4.4e-86 288.3 0.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GBG73855.1 - 2.8e-74 248.8 0.2 1.2e-73 246.8 0.0 1.9 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain GTP_EFTU PF00009.27 GBG73856.1 - 1.3e-62 210.9 0.0 1.8e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GBG73856.1 - 1.3e-30 105.7 0.0 3.8e-30 104.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 GBG73856.1 - 6.1e-21 74.3 0.0 1.6e-20 72.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GBG73856.1 - 5e-13 48.9 0.0 1.1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 GBG73856.1 - 1e-12 48.3 0.0 2.6e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG73856.1 - 0.0038 17.3 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RT_RNaseH PF17917.1 GBG73857.1 - 1.1e-29 102.9 0.2 1.4e-28 99.2 0.1 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73857.1 - 1.4e-29 102.0 0.0 1.1e-28 99.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Peptidase_M48 PF01435.18 GBG73857.1 - 1.5e-28 100.0 0.0 2.1e-15 57.0 0.0 2.9 3 0 0 3 3 3 2 Peptidase family M48 rve PF00665.26 GBG73857.1 - 9.8e-18 64.5 0.0 2.7e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG73857.1 - 5.4e-16 58.5 0.2 1e-15 57.6 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG73859.1 - 1.8e-05 24.4 0.1 5.4e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CdvA PF18822.1 GBG73859.1 - 0.11 12.3 4.1 0.12 12.2 2.2 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain CheZ PF04344.13 GBG73859.1 - 0.14 12.0 0.3 0.27 11.2 0.3 1.4 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ YkyA PF10368.9 GBG73859.1 - 0.25 11.0 4.9 0.43 10.2 4.9 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF659 PF04937.15 GBG73860.1 - 1.8e-36 125.3 0.0 3.4e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG73860.1 - 0.0014 18.6 0.7 0.004 17.2 0.7 1.8 1 0 0 1 1 1 1 BED zinc finger Antigen_Bd37 PF11641.8 GBG73860.1 - 0.097 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein DUF678 PF05077.12 GBG73860.1 - 3.7 7.8 5.5 1.8 8.8 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF678) Peptidase_C48 PF02902.19 GBG73861.1 - 0.00041 20.3 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Integrase_H2C2 PF17921.1 GBG73862.1 - 3e-14 52.8 1.1 6.3e-14 51.8 0.2 2.0 1 1 1 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG73862.1 - 0.027 14.7 0.7 0.054 13.7 0.7 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG73862.1 - 0.092 13.0 0.0 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein PC-Esterase PF13839.6 GBG73864.1 - 3e-59 201.1 0.9 7.1e-59 199.9 0.1 1.9 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 GBG73864.1 - 2.3e-14 53.4 3.7 9.1e-14 51.5 3.7 2.1 1 0 0 1 1 1 1 PMR5 N terminal Domain YL1 PF05764.13 GBG73865.1 - 0.068 13.3 23.5 0.098 12.8 23.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG73865.1 - 0.14 11.4 25.9 0.2 11.0 25.9 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG73865.1 - 0.83 7.9 19.1 1.2 7.3 19.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG73865.1 - 0.96 8.8 27.4 1.3 8.4 27.4 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG73865.1 - 2.3 7.7 13.3 3.7 7.0 13.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG73865.1 - 3 5.9 27.4 4 5.5 27.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG73865.1 - 5.1 6.7 19.6 7.6 6.2 19.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SURF2 PF05477.11 GBG73865.1 - 6 6.5 12.6 8.9 5.9 12.6 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SAPS PF04499.15 GBG73865.1 - 6.9 5.3 6.3 7.9 5.1 6.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDE_Tnp_4 PF13359.6 GBG73866.1 - 2.8e-30 105.1 0.0 5.5e-30 104.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73866.1 - 2.7e-15 56.5 0.0 4.3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG73866.1 - 0.00083 19.1 0.1 0.73 9.4 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain RVT_1 PF00078.27 GBG73868.1 - 4e-28 98.4 0.2 7.3e-28 97.6 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDH1_2_SANT_HL1 PF18375.1 GBG73868.1 - 0.99 10.1 6.1 3.2 8.5 0.1 3.2 3 1 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 DMPK_coil PF08826.10 GBG73868.1 - 1.7 8.8 7.9 0.49 10.5 0.3 3.0 2 0 0 2 2 2 0 DMPK coiled coil domain like Spc42p PF11544.8 GBG73868.1 - 1.8 8.6 9.0 0.29 11.2 4.6 2.0 2 0 0 2 2 2 0 Spindle pole body component Spc42p BUD22 PF09073.10 GBG73869.1 - 6.8 5.9 12.2 7.6 5.8 12.2 1.0 1 0 0 1 1 1 0 BUD22 DUF659 PF04937.15 GBG73870.1 - 1.6e-30 106.0 0.1 2.4e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73870.1 - 1.2e-08 34.6 0.1 2.6e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG73872.1 - 6.4e-37 127.2 0.1 1e-36 126.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73872.1 - 5.1e-19 68.2 0.0 1.9e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73872.1 - 6.5e-08 32.8 0.0 1.9e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Es2 PF09751.9 GBG73872.1 - 0.02 14.6 10.4 0.029 14.1 10.4 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 Presenilin PF01080.17 GBG73872.1 - 5 5.8 10.6 9.9 4.8 10.6 1.4 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 GBG73873.1 - 7.1 6.1 9.7 14 5.2 9.7 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Asp_protease_2 PF13650.6 GBG73874.1 - 1.8e-08 34.9 0.0 7e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73874.1 - 8e-08 32.1 0.0 1.8e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73874.1 - 6.8e-07 29.8 0.2 5.7e-06 26.8 0.0 2.7 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG73874.1 - 0.00012 21.9 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG73874.1 - 0.00099 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG73874.1 - 0.0044 17.3 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG73876.1 - 1.1e-29 103.5 0.0 2.2e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG73876.1 - 9.4e-21 74.1 0.0 3.4e-20 72.3 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73876.1 - 9.3e-18 64.1 0.2 2.1e-17 63.0 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG73876.1 - 2e-12 47.0 0.0 4.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73876.1 - 5.7e-10 39.4 0.1 5.1e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG73876.1 - 1.7e-07 31.1 0.0 3.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73876.1 - 0.0021 18.5 0.0 0.0061 17.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73876.1 - 0.0055 17.3 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease CCD48 PF15799.5 GBG73877.1 - 0.0011 17.4 2.2 0.0017 16.8 2.2 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 DUF848 PF05852.11 GBG73877.1 - 0.021 14.9 0.6 0.044 13.9 0.6 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) CCDC85 PF10226.9 GBG73877.1 - 0.029 14.0 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 CCDC85 family HALZ PF02183.18 GBG73877.1 - 0.076 13.2 1.2 0.076 13.2 1.2 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GBG73877.1 - 0.089 12.9 1.7 0.21 11.7 1.7 1.6 1 0 0 1 1 1 0 bZIP transcription factor XhlA PF10779.9 GBG73877.1 - 0.36 11.1 1.1 0.84 9.9 0.3 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DivIC PF04977.15 GBG73877.1 - 0.56 10.0 5.8 0.29 10.9 2.5 2.2 1 1 0 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 GBG73877.1 - 3.5 7.8 11.4 0.06 13.4 3.0 2.4 3 0 0 3 3 3 0 Basic region leucine zipper Integrase_H2C2 PF17921.1 GBG73878.1 - 7e-20 70.9 0.1 1.1e-19 70.2 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73878.1 - 2.5e-08 34.1 0.0 5.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG73878.1 - 0.0075 16.5 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger TTC5_OB PF16669.5 GBG73880.1 - 6.3e-24 83.9 0.0 1e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_16 PF13432.6 GBG73880.1 - 3.2e-07 30.9 2.3 0.058 14.1 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG73880.1 - 2.3e-06 27.2 4.1 0.022 14.5 0.0 5.1 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.17 GBG73880.1 - 4.9e-06 26.2 15.0 0.012 15.6 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG73880.1 - 5.6e-06 26.4 0.9 0.5 10.9 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG73880.1 - 0.00015 21.4 15.7 0.48 10.3 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 GBG73880.1 - 0.0013 19.2 0.5 0.75 10.3 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TOM20_plant PF06552.12 GBG73880.1 - 0.02 14.7 0.7 5 6.8 0.1 2.7 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_12 PF13424.6 GBG73880.1 - 0.15 12.4 1.6 9.4 6.6 0.1 3.8 2 2 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG73880.1 - 0.22 12.4 4.1 21 6.3 0.0 4.3 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG73880.1 - 0.24 11.7 8.9 74 3.9 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Sucrose_synth PF00862.19 GBG73881.1 - 1.7e-255 848.6 0.0 2.1e-255 848.3 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG73881.1 - 8.1e-33 113.4 0.0 1.8e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG73881.1 - 2.2e-12 47.6 0.0 7.6e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG73881.1 - 7.3e-07 29.5 0.0 2.1e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2095 PF09868.9 GBG73881.1 - 0.052 13.5 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) RsfS PF02410.15 GBG73884.1 - 1.5e-26 92.7 0.3 3.9e-26 91.4 0.3 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Ribosomal_L14 PF00238.19 GBG73885.1 - 1.5e-36 125.2 0.2 1.8e-36 124.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Beta_helix PF13229.6 GBG73886.1 - 1.5e-05 24.9 5.4 5.6e-05 23.1 5.4 2.0 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG73886.1 - 0.072 12.3 0.3 0.13 11.5 0.3 1.5 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DDE_Tnp_4 PF13359.6 GBG73887.1 - 5.9e-30 104.0 0.0 3.2e-29 101.6 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73887.1 - 2.6e-13 50.1 0.0 4.4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG73887.1 - 0.00017 21.3 0.5 0.48 10.0 0.0 3.0 3 0 0 3 3 3 2 Transposase DDE domain NnrU PF07298.11 GBG73888.1 - 1.3e-52 178.4 8.4 2.2e-52 177.7 8.4 1.3 1 0 0 1 1 1 1 NnrU protein PEMT PF04191.13 GBG73888.1 - 0.0013 19.1 0.1 0.0013 19.1 0.1 2.4 2 1 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 GBG73888.1 - 0.082 13.3 0.2 0.34 11.3 0.1 2.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF5624 PF18538.1 GBG73889.1 - 4.8 7.3 6.1 0.66 10.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) DUF659 PF04937.15 GBG73890.1 - 3.6e-22 78.9 0.2 7.9e-22 77.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG73890.1 - 0.14 11.9 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF2326 PF10088.9 GBG73890.1 - 0.17 11.7 0.4 1.1 8.9 0.4 2.1 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) Ion_trans PF00520.31 GBG73891.1 - 8.1e-11 41.6 0.1 1.2e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 GBG73891.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Peptidase_C48 PF02902.19 GBG73892.1 - 2.6e-32 112.4 0.1 4.2e-32 111.7 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RT_RNaseH PF17917.1 GBG73893.1 - 1e-19 70.7 0.0 2.2e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73893.1 - 1e-18 67.2 0.0 2.2e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73893.1 - 2.8e-15 56.1 0.1 8e-15 54.7 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73893.1 - 5.4e-14 52.4 0.0 2.8e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG73893.1 - 4e-08 33.7 0.0 1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG73893.1 - 6.8e-08 32.3 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG73893.1 - 2.1e-06 28.3 0.0 6.4e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG73893.1 - 0.0012 19.0 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG73893.1 - 0.0012 18.6 0.1 0.0026 17.6 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG73893.1 - 0.028 14.7 0.0 0.08 13.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease SlyX PF04102.12 GBG73893.1 - 0.1 13.3 4.0 0.7 10.6 0.0 4.1 3 0 0 3 3 3 0 SlyX CDC45 PF02724.14 GBG73893.1 - 2.1 6.5 6.7 3.9 5.7 6.7 1.3 1 0 0 1 1 1 0 CDC45-like protein LPP PF04728.13 GBG73894.1 - 0.025 15.0 0.5 4.6 7.7 0.1 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Retrotrans_gag PF03732.17 GBG73894.1 - 0.12 12.7 2.7 0.64 10.3 0.0 3.2 4 1 0 4 4 4 0 Retrotransposon gag protein ATG16 PF08614.11 GBG73894.1 - 0.14 12.3 8.3 0.37 11.0 0.4 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Phasin PF05597.11 GBG73894.1 - 0.26 11.3 1.6 0.66 10.0 1.6 1.7 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FUSC PF04632.12 GBG73894.1 - 0.83 8.1 2.9 1.2 7.6 2.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4404 PF14357.6 GBG73894.1 - 2 9.1 4.5 2.3 8.9 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) RP-C_C PF11800.8 GBG73894.1 - 3.6 7.6 6.1 2.6 8.1 0.1 2.8 2 1 1 3 3 3 0 Replication protein C C-terminal region gag-asp_proteas PF13975.6 GBG73896.1 - 5.8e-08 33.2 0.0 1.5e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG73896.1 - 8.5e-06 26.3 0.0 2.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG73896.1 - 0.00093 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG73896.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG73896.1 - 5.1 7.4 5.9 0.77 9.9 1.9 1.8 2 0 0 2 2 2 0 Zinc knuckle Sec8_exocyst PF04048.14 GBG73897.1 - 0.016 15.1 0.3 0.016 15.1 0.3 1.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Senescence_reg PF04520.13 GBG73897.1 - 0.024 15.5 1.7 0.024 15.5 1.7 1.8 2 0 0 2 2 2 0 Senescence regulator DivIC PF04977.15 GBG73897.1 - 0.062 13.1 0.5 0.062 13.1 0.5 3.1 2 1 0 3 3 3 0 Septum formation initiator DUF948 PF06103.11 GBG73897.1 - 0.15 12.3 0.8 0.33 11.2 0.8 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RPW8 PF05659.11 GBG73897.1 - 0.21 11.2 6.4 0.77 9.4 0.2 2.6 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Rootletin PF15035.6 GBG73897.1 - 0.37 10.8 15.7 0.79 9.7 15.7 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lectin_N PF03954.14 GBG73897.1 - 1.6 8.5 5.0 0.26 11.0 0.5 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain YabA PF06156.13 GBG73897.1 - 2.3 8.9 10.6 0.11 13.1 2.3 2.6 2 1 0 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 GBG73897.1 - 3.3 7.9 13.2 0.12 12.6 5.1 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PsbP PF01789.16 GBG73898.1 - 7.1e-11 42.5 0.0 1.2e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 PsbP RT_RNaseH_2 PF17919.1 GBG73900.1 - 2e-25 88.7 0.0 5.1e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73900.1 - 3.7e-24 85.0 0.0 1.1e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73900.1 - 1.1e-17 63.9 0.3 2.5e-17 62.7 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Adap_comp_sub PF00928.21 GBG73900.1 - 3.9e-11 42.8 0.0 6.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RVT_1 PF00078.27 GBG73900.1 - 1.1e-10 41.4 0.0 2.5e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73900.1 - 1.7e-08 34.7 0.1 8.2e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG73900.1 - 0.00022 21.4 1.2 0.042 14.1 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein Clat_adaptor_s PF01217.20 GBG73900.1 - 0.00032 20.7 0.0 0.00069 19.6 0.0 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-H2C2 PF09337.10 GBG73900.1 - 0.021 15.0 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger FAM76 PF16046.5 GBG73900.1 - 0.09 12.1 5.0 0.25 10.7 5.0 1.7 1 0 0 1 1 1 0 FAM76 protein WASH-7_N PF14745.6 GBG73900.1 - 0.13 10.7 0.1 0.22 10.0 0.1 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal RT_RNaseH_2 PF17919.1 GBG73901.1 - 2e-25 88.7 0.0 5.2e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73901.1 - 3.8e-24 85.0 0.0 1.1e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73901.1 - 1.1e-17 63.8 0.3 2.6e-17 62.7 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Adap_comp_sub PF00928.21 GBG73901.1 - 9.7e-15 54.6 0.0 1.6e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RVT_1 PF00078.27 GBG73901.1 - 1.2e-10 41.3 0.0 2.6e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73901.1 - 1.8e-08 34.6 0.1 8.4e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG73901.1 - 0.00023 21.4 1.2 0.043 14.1 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein Clat_adaptor_s PF01217.20 GBG73901.1 - 0.00033 20.6 0.0 0.0007 19.5 0.0 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-H2C2 PF09337.10 GBG73901.1 - 0.021 15.0 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger WASH-7_N PF14745.6 GBG73901.1 - 0.13 10.7 0.1 0.23 9.9 0.1 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal FAM76 PF16046.5 GBG73901.1 - 0.36 10.1 6.9 0.99 8.7 6.9 1.6 1 0 0 1 1 1 0 FAM76 protein RVT_1 PF00078.27 GBG73902.1 - 1.3e-31 109.9 0.1 1.8e-31 109.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73903.1 - 1.3e-18 67.4 0.0 2.6e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG73903.1 - 0.0013 18.9 0.2 0.0041 17.3 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG73904.1 - 5.6e-20 71.3 0.0 1.4e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73904.1 - 7.3e-20 71.2 0.0 2.3e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73904.1 - 1.2e-15 57.3 2.1 1.4e-15 57.1 0.5 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG73904.1 - 7.2e-11 42.3 0.0 1.9e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG73904.1 - 0.012 15.8 0.1 0.028 14.6 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG73904.1 - 0.04 13.4 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG73904.1 - 0.044 14.0 0.1 0.044 14.0 0.1 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein RVP_2 PF08284.11 GBG73904.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Adap_comp_sub PF00928.21 GBG73905.1 - 1.1e-23 84.0 0.1 2.8e-12 46.6 0.2 2.4 2 0 0 2 2 2 2 Adaptor complexes medium subunit family RVP_2 PF08284.11 GBG73905.1 - 5e-18 65.2 0.0 4.9e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73905.1 - 1.5e-12 48.0 0.0 1.6e-05 25.4 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG73905.1 - 9.7e-10 38.9 0.0 0.00045 20.7 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG73905.1 - 2.1e-05 24.7 0.0 0.35 11.2 0.0 2.8 2 0 0 2 2 2 2 Retrotransposon gag protein DUF2294 PF10057.9 GBG73905.1 - 0.0055 16.8 0.8 0.015 15.4 0.5 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2294) Trans_reg_C PF00486.28 GBG73905.1 - 0.03 14.4 0.5 0.076 13.1 0.5 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal ZapD PF07072.11 GBG73905.1 - 0.51 10.0 6.8 0.43 10.3 4.7 2.0 2 1 0 2 2 2 0 Cell division protein NPV_P10 PF05531.12 GBG73905.1 - 4 8.0 10.9 8.9 6.9 0.2 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Histone PF00125.24 GBG73907.1 - 2.5e-15 57.0 0.1 2.5e-15 57.0 0.1 3.4 4 0 0 4 4 4 1 Core histone H2A/H2B/H3/H4 DUF835 PF05763.12 GBG73907.1 - 0.16 11.7 0.1 0.81 9.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF835) zf-CCHC PF00098.23 GBG73907.1 - 0.3 11.3 1.9 0.9 9.7 1.9 1.8 1 0 0 1 1 1 0 Zinc knuckle YabA PF06156.13 GBG73909.1 - 0.1 13.2 1.3 1.1 9.9 0.1 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Integrase_H2C2 PF17921.1 GBG73911.1 - 2.4e-18 66.0 0.1 5.6e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG73911.1 - 2.4e-16 59.9 0.3 5.2e-16 58.8 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73911.1 - 3.3e-10 39.9 0.0 7.8e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73911.1 - 2.9e-06 27.5 0.5 0.016 15.4 0.1 2.6 1 1 1 2 2 2 2 Integrase core domain DUF1564 PF07600.11 GBG73911.1 - 0.00037 20.2 0.8 0.0017 18.1 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG73913.1 - 4.7e-36 124.4 0.1 9.1e-36 123.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73913.1 - 7e-25 87.5 0.0 8.4e-16 58.2 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH PF17917.1 GBG73913.1 - 1.3e-19 70.4 0.5 7.5e-19 68.0 0.2 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73913.1 - 6.6e-16 58.2 2.2 1.5e-15 57.0 2.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG73913.1 - 3.9e-10 39.6 0.1 2.1e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG73913.1 - 0.044 14.0 0.7 0.13 12.5 0.7 1.8 1 0 0 1 1 1 0 H2C2 zinc finger DUF1043 PF06295.12 GBG73913.1 - 0.22 11.5 7.2 1.2 9.1 7.2 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) RT_RNaseH_2 PF17919.1 GBG73914.1 - 1.3e-29 102.1 0.1 5.5e-29 100.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73914.1 - 5.8e-26 90.8 0.3 1.3e-25 89.7 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73914.1 - 2.3e-17 62.8 0.4 4.7e-17 61.8 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73914.1 - 9.6e-15 54.8 0.0 2.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG73914.1 - 0.00048 20.3 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger WD40 PF00400.32 GBG73915.1 - 0.00012 22.8 0.3 0.36 11.8 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG73915.1 - 0.065 13.5 0.0 0.83 10.0 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain gag-asp_proteas PF13975.6 GBG73916.1 - 0.052 14.1 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Uds1 PF15456.6 GBG73916.1 - 0.47 10.6 3.3 0.49 10.6 0.5 2.1 2 0 0 2 2 2 0 Up-regulated During Septation RVT_1 PF00078.27 GBG73917.1 - 6.3e-31 107.6 0.2 2.8e-28 98.9 0.1 3.3 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG73917.1 - 8.5e-27 93.7 0.0 1.6e-15 57.3 0.0 3.3 3 0 0 3 3 3 2 Integrase core domain rve_3 PF13683.6 GBG73917.1 - 1.1e-06 28.4 1.4 0.033 14.0 0.0 4.1 4 0 0 4 4 4 2 Integrase core domain ABC_tran_CTD PF16326.5 GBG73917.1 - 0.081 13.2 1.3 0.4 11.0 1.3 2.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain Integrase_H2C2 PF17921.1 GBG73918.1 - 5.9e-17 61.5 0.1 1.2e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG73918.1 - 3.9e-13 49.6 0.1 1.2e-12 48.0 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG73918.1 - 8.1e-07 29.6 0.0 2.6e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG73918.1 - 1.4e-06 28.2 0.0 4.8e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG73918.1 - 2.5e-06 27.3 0.0 6.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73918.1 - 7.1e-05 23.3 0.0 0.00026 21.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG73918.1 - 8e-05 22.8 0.1 0.00041 20.6 0.1 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein SlyX PF04102.12 GBG73918.1 - 0.0055 17.3 1.5 0.0055 17.3 1.5 3.0 2 1 1 3 3 3 1 SlyX Asp_protease PF09668.10 GBG73918.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG73918.1 - 0.063 12.8 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73919.1 - 1e-20 73.6 0.2 2.6e-20 72.3 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG73919.1 - 2.7e-12 46.9 0.6 7e-12 45.6 0.6 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG73919.1 - 1.1e-05 25.6 6.8 0.0019 18.4 0.1 5.0 5 0 0 5 5 5 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG73919.1 - 0.0002 21.5 0.0 0.001 19.2 0.0 2.3 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG73919.1 - 0.0009 19.2 0.1 0.0024 17.9 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73919.1 - 0.00092 19.4 0.0 0.00092 19.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DUF1564 PF07600.11 GBG73919.1 - 0.029 14.0 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RT_RNaseH_2 PF17919.1 GBG73920.1 - 3.2e-29 100.9 0.0 8.5e-29 99.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73920.1 - 3.9e-28 97.8 0.2 2.4e-27 95.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73920.1 - 1.1e-18 67.5 0.0 2.6e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG73920.1 - 1.5e-16 60.2 0.7 3.7e-16 59.0 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG73920.1 - 0.0013 18.3 0.1 0.003 17.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG73920.1 - 0.12 11.9 0.1 0.12 11.9 0.1 3.2 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2870 PF11069.8 GBG73921.1 - 0.24 11.8 4.6 0.49 10.8 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Integrase_H2C2 PF17921.1 GBG73922.1 - 6.2e-18 64.7 0.2 1.2e-17 63.8 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG73922.1 - 3.8e-14 52.8 0.8 8.5e-14 51.7 0.8 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG73922.1 - 2.5e-13 50.3 0.0 7.5e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG73922.1 - 2.5e-05 24.2 0.1 2.5e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG73922.1 - 0.025 14.8 0.0 0.069 13.4 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger NHase_beta PF02211.15 GBG73922.1 - 0.027 14.5 0.4 0.067 13.2 0.2 1.8 2 0 0 2 2 2 0 Nitrile hydratase beta subunit RT_RNaseH PF17917.1 GBG73923.1 - 6.2e-30 103.6 0.0 2e-29 102.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG73923.1 - 2e-26 91.9 0.8 7e-26 90.2 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG73923.1 - 1.7e-22 80.0 0.0 3.4e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG73923.1 - 2.5e-17 62.7 0.1 5.8e-17 61.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73923.1 - 9.6e-12 45.1 0.0 2.5e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain RVP_2 PF08284.11 GBG73923.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG73923.1 - 0.23 11.7 8.6 24 5.3 0.1 4.3 4 0 0 4 4 4 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG73924.1 - 9.8e-35 120.1 0.1 1.7e-34 119.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73924.1 - 4.6e-32 110.0 0.0 1.8e-31 108.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73924.1 - 2.6e-31 108.0 0.1 6.3e-31 106.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG73924.1 - 0.13 11.9 0.1 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-CCHC_3 PF13917.6 GBG73924.1 - 0.18 11.8 0.9 0.4 10.7 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG73925.1 - 1e-18 67.2 0.1 3.3e-18 65.5 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG73925.1 - 0.023 15.0 0.0 0.14 12.4 0.0 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein Rad60-SLD PF11976.8 GBG73925.1 - 0.11 12.4 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF1664 PF07889.12 GBG73925.1 - 0.15 12.1 0.3 3.4 7.7 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) zf-H2C2 PF09337.10 GBG73925.1 - 0.17 12.2 0.5 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger RVP PF00077.20 GBG73925.1 - 0.18 12.1 0.0 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG73925.1 - 0.18 12.3 0.0 0.45 11.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG73925.1 - 8.2 6.4 6.6 0.49 10.3 0.6 2.2 2 0 0 2 2 2 0 Zinc knuckle RVP_2 PF08284.11 GBG73926.1 - 2.9e-07 30.3 0.0 6.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG73926.1 - 1.1e-06 29.1 0.0 4.6e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG73926.1 - 8.4e-06 26.3 0.0 3.1e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG73926.1 - 0.0034 17.6 2.9 0.01 16.1 0.0 3.0 3 1 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG73926.1 - 0.0072 15.9 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4407 PF14362.6 GBG73926.1 - 2.9 7.2 12.3 6.5 6.0 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CLZ PF16526.5 GBG73926.1 - 4.6 7.7 11.0 0.24 11.8 0.9 3.5 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KBP_C PF12309.8 GBG73927.1 - 8.7e-41 140.6 0.1 1.2e-40 140.2 0.1 1.2 1 0 0 1 1 1 1 KIF-1 binding protein C terminal DUF898 PF05987.13 GBG73929.1 - 0.039 13.0 3.5 0.061 12.4 3.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Myb_DNA-bind_4 PF13837.6 GBG73930.1 - 3.9e-12 46.4 5.1 7.4e-12 45.5 5.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG73930.1 - 0.0064 16.7 0.6 0.012 15.8 0.6 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 GBG73930.1 - 0.039 14.9 2.8 0.07 14.1 2.8 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG73930.1 - 4.2 7.7 6.3 0.94 9.8 0.9 2.4 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF659 PF04937.15 GBG73931.1 - 4.4e-20 72.1 0.5 7.3e-19 68.1 0.5 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) PPV_E2_C PF00511.17 GBG73931.1 - 0.026 14.7 0.0 7.7 6.8 0.0 2.8 2 0 0 2 2 2 0 E2 (early) protein, C terminal zf-BED PF02892.15 GBG73931.1 - 0.058 13.4 0.3 12 6.0 0.0 2.7 2 0 0 2 2 2 0 BED zinc finger RcpC PF16976.5 GBG73931.1 - 0.11 12.5 0.1 22 5.1 0.0 2.6 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB zinc_ribbon_4 PF13717.6 GBG73931.1 - 0.21 11.5 1.9 22 5.1 0.0 3.1 4 0 0 4 4 4 0 zinc-ribbon domain EIN3 PF04873.13 GBG73932.1 - 2.6e-121 403.7 7.7 3.6e-121 403.3 7.7 1.2 1 0 0 1 1 1 1 Ethylene insensitive 3 DUF2841 PF11001.8 GBG73932.1 - 0.00015 21.8 4.0 0.00022 21.3 1.4 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2841) Dimer_Tnp_hAT PF05699.14 GBG73935.1 - 1.3e-08 34.5 0.2 2.4e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PPL5 PF18168.1 GBG73935.1 - 1.3 8.2 5.6 1.9 7.7 5.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Myb_DNA-bind_4 PF13837.6 GBG73937.1 - 4.8e-10 39.7 1.6 6.2e-09 36.1 1.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG73937.1 - 4.1e-05 23.6 1.8 9.2e-05 22.5 1.8 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG73937.1 - 0.0034 17.7 0.6 0.0081 16.5 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like TxDE PF18711.1 GBG73937.1 - 0.12 12.5 0.0 3.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Toxoflavin-degrading enzyme DDE_Tnp_4 PF13359.6 GBG73938.1 - 1.1e-25 90.2 0.0 8.1e-25 87.3 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG73938.1 - 1.2e-06 28.3 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG73938.1 - 0.031 13.9 0.5 0.94 9.1 0.5 2.4 2 0 0 2 2 2 0 Transposase DDE domain GNAT_acetyltr_2 PF13718.6 GBG73939.1 - 0.26 10.7 2.1 0.83 9.0 2.1 1.8 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Toprim_4 PF13662.6 GBG73939.1 - 0.26 11.8 3.4 3.5 8.2 0.1 3.3 3 0 0 3 3 3 0 Toprim domain Prothymosin PF03247.14 GBG73941.1 - 1.4 9.4 25.2 3.4 8.2 21.6 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family RT_RNaseH_2 PF17919.1 GBG73943.1 - 1e-27 96.1 0.0 1.9e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73943.1 - 1.8e-25 89.2 0.0 3.1e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BUD22 PF09073.10 GBG73943.1 - 0.046 13.1 37.9 0.065 12.6 37.9 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG73943.1 - 2 7.8 40.2 3.3 7.0 40.2 1.3 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG73943.1 - 2.9 7.4 18.7 4.4 6.8 18.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG73943.1 - 10 4.2 42.1 14 3.7 42.1 1.1 1 0 0 1 1 1 0 Nop14-like family NRDE-2 PF08424.10 GBG73944.1 - 0.15 11.1 1.5 0.21 10.7 1.5 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference FSA_C PF10479.9 GBG73945.1 - 1.1 7.3 6.7 1.5 6.9 6.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus COPI_C PF06957.11 GBG73945.1 - 9.5 4.9 10.0 3.4 6.3 7.2 1.5 1 1 1 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus DUF659 PF04937.15 GBG73946.1 - 7.6e-29 100.5 0.1 1.1e-28 100.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG73947.1 - 0.037 14.1 0.1 0.076 13.1 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF935 PF06074.12 GBG73947.1 - 0.084 11.6 10.0 0.11 11.2 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Nucleoside_tran PF01733.18 GBG73947.1 - 5.6 6.2 5.6 4.4 6.6 4.7 1.3 1 1 0 1 1 1 0 Nucleoside transporter CDC45 PF02724.14 GBG73948.1 - 0.051 11.9 37.9 0.11 10.7 15.9 2.2 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 GBG73948.1 - 1.4 8.2 52.3 0.55 9.6 22.1 2.1 2 0 0 2 2 2 0 SDA1 DUF3807 PF12720.7 GBG73948.1 - 4 7.7 35.8 0.18 12.1 13.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Auxin_resp PF06507.13 GBG73949.1 - 5.8e-30 103.4 0.6 1.7e-29 101.9 0.6 1.9 1 0 0 1 1 1 1 Auxin response factor B3 PF02362.21 GBG73949.1 - 1.5e-21 76.1 0.0 4e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 B3 DNA binding domain AUX_IAA PF02309.16 GBG73949.1 - 4.4e-08 33.3 0.0 0.0014 18.6 0.0 2.4 1 1 1 2 2 2 2 AUX/IAA family MID_MedPIWI PF18296.1 GBG73950.1 - 0.057 13.2 11.2 0.18 11.6 9.1 2.0 1 1 1 2 2 2 0 MID domain of medPIWI Presenilin PF01080.17 GBG73950.1 - 0.061 12.1 1.6 0.084 11.6 1.6 1.3 1 0 0 1 1 1 0 Presenilin eIF_4EBP PF05456.11 GBG73950.1 - 0.29 11.1 8.4 0.09 12.7 3.2 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF4834 PF16118.5 GBG73950.1 - 0.34 11.9 10.2 3.1 8.8 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TRM13 PF05206.14 GBG73950.1 - 0.91 9.0 6.1 2.9 7.3 0.6 2.1 2 0 0 2 2 2 0 Methyltransferase TRM13 DUF1980 PF09323.10 GBG73950.1 - 6.6 6.6 6.9 17 5.3 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) IFT57 PF10498.9 GBG73951.1 - 2e-121 405.4 1.2 2.3e-121 405.2 0.0 1.6 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 AAA_13 PF13166.6 GBG73951.1 - 0.00096 17.9 4.1 0.0017 17.1 4.1 1.4 1 0 0 1 1 1 1 AAA domain Prefoldin_2 PF01920.20 GBG73951.1 - 0.0026 17.7 2.1 0.0026 17.7 2.1 4.6 3 1 2 5 5 4 1 Prefoldin subunit Spc7 PF08317.11 GBG73951.1 - 0.0036 16.2 12.7 0.0036 16.2 12.7 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Lebercilin PF15619.6 GBG73951.1 - 0.006 16.3 12.8 0.006 16.3 12.8 1.9 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 GBG73951.1 - 0.0084 16.1 9.9 0.64 10.1 1.5 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) DUF87 PF01935.17 GBG73951.1 - 0.024 14.7 1.5 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Baculo_PEP_C PF04513.12 GBG73951.1 - 0.025 14.6 4.3 0.34 10.9 4.3 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 GBG73951.1 - 0.073 13.1 22.0 0.046 13.8 11.1 3.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 GBG73951.1 - 0.11 10.7 11.4 0.048 11.8 6.6 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Erp_C PF06780.11 GBG73951.1 - 0.15 12.1 5.5 0.47 10.5 4.1 2.2 1 1 1 2 2 2 0 Erp protein C-terminus Sec20 PF03908.13 GBG73951.1 - 0.22 11.5 2.1 0.5 10.3 0.9 2.1 1 1 1 2 2 2 0 Sec20 DUF1759 PF03564.15 GBG73951.1 - 0.23 11.4 1.7 0.41 10.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) LRRFIP PF09738.9 GBG73951.1 - 0.36 10.3 19.3 0.012 15.1 7.6 2.8 2 1 1 3 3 3 0 LRRFIP family SpecificRecomb PF10136.9 GBG73951.1 - 0.55 8.5 4.0 0.95 7.7 4.0 1.3 1 0 0 1 1 1 0 Site-specific recombinase DUF948 PF06103.11 GBG73951.1 - 0.69 10.2 9.4 0.84 9.9 3.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 GBG73951.1 - 0.76 10.2 19.9 0.076 13.5 11.6 2.6 2 1 0 2 2 2 0 Fez1 DUF4164 PF13747.6 GBG73951.1 - 0.93 9.8 7.3 1.2 9.5 1.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Prominin PF05478.11 GBG73951.1 - 0.93 7.4 6.6 1.4 6.8 6.6 1.2 1 0 0 1 1 1 0 Prominin Sulfatase_C PF14707.6 GBG73951.1 - 1 10.1 5.1 9.8 6.9 2.6 3.1 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Exonuc_VII_L PF02601.15 GBG73951.1 - 1.6 8.3 12.7 0.27 10.8 7.4 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Sec8_exocyst PF04048.14 GBG73951.1 - 2.2 8.2 11.5 0.61 10.0 0.9 2.8 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Laminin_II PF06009.12 GBG73951.1 - 2.8 7.9 10.7 16 5.5 4.6 2.5 1 1 2 3 3 3 0 Laminin Domain II YojJ PF10372.9 GBG73951.1 - 3.4 7.8 8.2 27 4.9 0.5 3.7 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus NPV_P10 PF05531.12 GBG73951.1 - 3.4 8.2 9.1 8.8 6.9 1.7 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.20 GBG73951.1 - 4 6.7 18.3 0.55 9.5 3.8 3.4 2 1 2 4 4 4 0 Tropomyosin FemAB PF02388.16 GBG73951.1 - 5.1 5.9 8.1 0.31 9.9 2.9 1.8 2 0 0 2 2 2 0 FemAB family CENP-H PF05837.12 GBG73951.1 - 5.1 7.5 17.5 0.1 13.0 6.6 3.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 GBG73951.1 - 6.9 5.4 4.6 11 4.8 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein COG2 PF06148.11 GBG73951.1 - 8.3 6.5 9.0 35 4.5 0.7 2.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6_N PF17675.1 GBG73951.1 - 8.9 6.8 21.5 0.14 12.7 8.5 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region Xan_ur_permease PF00860.20 GBG73952.1 - 7.4e-58 196.1 19.0 4.5e-57 193.5 19.0 2.2 1 1 0 1 1 1 1 Permease family BUD22 PF09073.10 GBG73952.1 - 0.0019 17.6 12.2 0.0019 17.6 12.2 3.0 3 0 0 3 3 3 2 BUD22 Cwf_Cwc_15 PF04889.12 GBG73952.1 - 0.34 10.6 47.7 0.022 14.5 11.8 2.8 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CD20 PF04103.15 GBG73952.1 - 8.5 6.5 17.3 20 5.2 2.5 4.5 4 0 0 4 4 4 0 CD20-like family Xan_ur_permease PF00860.20 GBG73953.1 - 1.9e-57 194.8 20.4 1.1e-56 192.2 20.4 2.2 1 1 0 1 1 1 1 Permease family Cwf_Cwc_15 PF04889.12 GBG73953.1 - 0.0038 17.0 25.2 0.021 14.6 11.8 2.6 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG73953.1 - 2.3 7.6 28.9 2.8 7.3 15.3 2.5 2 0 0 2 2 2 0 SDA1 Pro_isomerase PF00160.21 GBG73954.1 - 6.8e-30 104.4 0.2 1.5e-29 103.3 0.2 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 GBG73955.1 - 6.8e-30 104.4 0.2 1.5e-29 103.3 0.2 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 GBG73956.1 - 9.1e-21 74.8 0.0 2.1e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ion_trans PF00520.31 GBG73957.1 - 9.3e-14 51.2 12.1 1.4e-13 50.7 12.1 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 GBG73957.1 - 0.0026 17.8 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain tRNA-synt_1 PF00133.22 GBG73958.1 - 1.3e-197 657.8 0.0 1.3e-89 301.1 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GBG73958.1 - 9.3e-27 93.9 0.2 7.5e-26 90.9 0.0 2.4 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GBG73958.1 - 7.8e-13 47.9 1.0 5.5e-06 25.4 0.1 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GBG73958.1 - 0.00071 19.0 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain OCRE PF17780.1 GBG73959.1 - 2.5e-11 43.4 5.8 4.8e-11 42.5 5.8 1.4 1 0 0 1 1 1 1 OCRE domain zf-U1 PF06220.12 GBG73959.1 - 5.5e-09 35.6 0.2 1.1e-08 34.7 0.2 1.5 1 0 0 1 1 1 1 U1 zinc finger NOA36 PF06524.12 GBG73960.1 - 3.7 6.8 4.8 5.6 6.2 4.8 1.2 1 0 0 1 1 1 0 NOA36 protein Plavaka PF18759.1 GBG73962.1 - 1.4e-13 50.8 0.4 2.1e-13 50.2 0.4 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF2284 PF10050.9 GBG73962.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Pkinase PF00069.25 GBG73963.1 - 3.6e-48 164.2 0.0 1.3e-47 162.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG73963.1 - 2e-41 142.0 0.0 4.8e-41 140.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase zf-CCHC PF00098.23 GBG73963.1 - 1.9e-06 27.7 4.0 4.5e-06 26.5 4.0 1.7 1 0 0 1 1 1 1 Zinc knuckle APH PF01636.23 GBG73963.1 - 0.011 15.6 2.9 3.1 7.7 0.1 3.7 3 1 1 4 4 4 0 Phosphotransferase enzyme family ABC1 PF03109.16 GBG73963.1 - 0.025 14.7 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family TFIIA PF03153.13 GBG73963.1 - 7.9 6.4 24.0 15 5.4 24.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MOZ_SAS PF01853.18 GBG73965.1 - 3.9e-86 287.3 0.4 5.7e-86 286.7 0.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GBG73965.1 - 1.8e-23 81.9 1.0 4e-23 80.8 1.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 GBG73965.1 - 8e-20 70.5 0.5 1.5e-19 69.6 0.5 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 GBG73965.1 - 0.0048 17.3 0.0 0.0097 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GBG73965.1 - 0.077 13.2 0.1 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Chromo PF00385.24 GBG73965.1 - 0.13 12.2 0.2 1 9.3 0.1 2.2 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain DDRGK PF09756.9 GBG73965.1 - 0.34 10.5 2.5 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 DDRGK domain Mito_carr PF00153.27 GBG73966.1 - 1.1e-45 153.5 2.6 2.1e-17 62.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GBG73966.1 - 0.0013 18.0 0.2 0.58 9.3 0.0 3.1 3 0 0 3 3 3 2 Gammaproteobacterial serine protease Ribosomal_60s PF00428.19 GBG73968.1 - 5.7 7.6 9.3 9.1 7.0 0.5 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pyr_redox_2 PF07992.14 GBG73969.1 - 2.3e-32 112.4 1.8 2.2e-26 92.8 1.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG73969.1 - 2.1e-10 41.0 1.8 3.2e-08 34.0 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG73969.1 - 0.0013 18.1 0.1 0.0013 18.1 0.1 2.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Zip PF02535.22 GBG73969.1 - 0.0069 15.7 12.5 0.014 14.6 12.5 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter NAD_binding_7 PF13241.6 GBG73969.1 - 0.0087 16.5 0.1 8.1 6.9 0.0 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GBG73969.1 - 0.012 14.7 1.5 0.55 9.2 0.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 GBG73969.1 - 0.018 13.9 0.4 1.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 GBG73969.1 - 0.14 11.3 0.0 0.14 11.3 0.0 3.8 3 1 1 4 4 3 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 GBG73969.1 - 0.26 11.6 1.3 38 4.6 0.1 3.3 3 0 0 3 3 3 0 TrkA-N domain DUF778 PF05608.12 GBG73969.1 - 0.98 9.8 11.4 0.14 12.5 6.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF778) MMR1 PF08505.10 GBG73969.1 - 7.3 6.8 22.2 20 5.3 22.2 1.7 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PAT1 PF09770.9 GBG73969.1 - 8.8 4.4 33.0 13 3.9 33.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 GBG73969.1 - 9.2 4.8 11.3 17 3.9 11.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dimer_Tnp_hAT PF05699.14 GBG73970.1 - 0.00018 21.2 0.2 0.00048 19.9 0.2 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Smr PF01713.21 GBG73971.1 - 2.5e-08 34.1 0.1 9e-08 32.4 0.1 2.0 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 GBG73971.1 - 1.6e-06 27.7 0.0 5.4e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 CUE domain DUF1771 PF08590.10 GBG73971.1 - 1e-05 25.8 10.9 2.9e-05 24.4 10.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DMA PF03474.14 GBG73971.1 - 0.019 14.6 0.0 0.096 12.3 0.0 2.0 2 0 0 2 2 2 0 DMRTA motif PSI_PsaE PF02427.17 GBG73972.1 - 2.9e-33 113.3 1.9 2.9e-33 113.3 1.9 1.5 2 0 0 2 2 2 1 Photosystem I reaction centre subunit IV / PsaE Ribosomal_60s PF00428.19 GBG73972.1 - 7.5 7.2 12.8 0.53 10.9 1.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein PQ-loop PF04193.14 GBG73974.1 - 0.0048 16.6 1.0 0.012 15.4 0.8 1.9 1 1 0 1 1 1 1 PQ loop repeat PsbM PF05151.12 GBG73974.1 - 0.25 11.2 1.6 2.6 7.9 0.1 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) RVT_1 PF00078.27 GBG73975.1 - 9.6e-32 110.3 0.1 1.7e-31 109.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG73975.1 - 6.8e-30 103.1 0.0 2.5e-29 101.2 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73975.1 - 7.6e-28 96.9 0.0 2.6e-27 95.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG73975.1 - 0.00042 20.4 0.0 0.00097 19.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain LAB_N PF07578.11 GBG73976.1 - 0.052 13.6 0.2 0.094 12.8 0.2 1.4 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain LAB_N PF07578.11 GBG73977.1 - 0.053 13.6 0.2 0.096 12.8 0.2 1.4 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain gag-asp_proteas PF13975.6 GBG73978.1 - 0.0022 18.5 0.0 0.0047 17.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG73978.1 - 0.0049 16.6 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Prenyltrans PF00432.21 GBG73979.1 - 2.6e-67 222.2 18.5 1.5e-14 53.4 0.6 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GBG73979.1 - 0.00074 18.7 0.0 0.057 12.5 0.0 2.4 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GBG73979.1 - 0.0008 18.6 0.0 0.12 11.4 0.0 2.8 2 2 3 5 5 5 3 Squalene-hopene cyclase N-terminal domain Rop PF01815.16 GBG73979.1 - 0.021 14.7 2.1 5.8 6.9 0.2 3.2 3 0 0 3 3 3 0 Rop protein ZnuA PF01297.17 GBG73981.1 - 0.15 11.4 0.2 0.22 10.9 0.2 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Integrase_H2C2 PF17921.1 GBG73982.1 - 1.1e-17 63.8 0.1 3.2e-17 62.4 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG73982.1 - 2.1e-14 53.8 0.0 5.8e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Dpy-30 PF05186.13 GBG73982.1 - 3.2e-06 26.7 0.1 7.2e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 Dpy-30 motif zf-H2C2 PF09337.10 GBG73982.1 - 0.016 15.5 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger CCDC24 PF15669.5 GBG73982.1 - 0.31 10.9 8.8 4.1 7.2 4.5 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Mucin PF01456.17 GBG73983.1 - 0.032 14.2 15.1 0.058 13.4 15.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Presenilin PF01080.17 GBG73984.1 - 0.3 9.8 0.1 0.33 9.7 0.1 1.0 1 0 0 1 1 1 0 Presenilin SseC PF04888.12 GBG73984.1 - 1.2 8.7 7.0 2.5 7.6 7.0 1.6 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family RR_TM4-6 PF06459.12 GBG73984.1 - 8.7 6.1 9.0 13 5.5 9.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EF-hand_1 PF00036.32 GBG73985.1 - 2.4e-09 36.1 2.0 0.00011 21.5 0.7 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GBG73985.1 - 5.7e-09 36.3 1.1 1.2e-08 35.3 1.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG73985.1 - 1.8e-08 33.7 1.2 0.0018 18.1 0.6 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GBG73985.1 - 0.00057 19.3 4.6 0.0014 18.0 0.4 2.9 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 GBG73985.1 - 0.00086 19.1 1.3 0.013 15.4 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GBG73985.1 - 0.21 11.9 0.3 6.8 7.1 0.0 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Got1 PF04178.12 GBG73987.1 - 2.4e-35 121.4 17.9 3e-35 121.0 17.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4064 PF13273.6 GBG73987.1 - 1 9.7 11.2 12 6.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Ribosomal_L6 PF00347.23 GBG73988.1 - 1.1e-28 99.7 0.3 6.3e-13 49.2 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 RVT_1 PF00078.27 GBG73989.1 - 5e-30 104.7 0.1 7.5e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Homeodomain PF00046.29 GBG73989.1 - 4.6e-15 55.2 0.8 1.1e-14 54.0 0.8 1.6 1 0 0 1 1 1 1 Homeodomain DDT PF02791.17 GBG73989.1 - 1.3e-14 54.2 1.8 2.3e-14 53.4 1.8 1.4 1 0 0 1 1 1 1 DDT domain HARE-HTH PF05066.13 GBG73989.1 - 1.1e-12 48.1 0.0 2.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain WSD PF15613.6 GBG73989.1 - 1.9e-10 41.1 0.3 1.9e-10 41.1 0.3 3.8 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 GBG73989.1 - 2.5e-06 26.9 0.0 6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Homeobox_KN PF05920.11 GBG73989.1 - 0.0017 18.2 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain RVT_1 PF00078.27 GBG73990.1 - 5e-30 104.7 0.1 7.5e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Homeodomain PF00046.29 GBG73990.1 - 4.5e-15 55.2 0.8 1.1e-14 54.0 0.8 1.6 1 0 0 1 1 1 1 Homeodomain DDT PF02791.17 GBG73990.1 - 1.3e-14 54.2 1.8 2.3e-14 53.4 1.8 1.4 1 0 0 1 1 1 1 DDT domain HARE-HTH PF05066.13 GBG73990.1 - 1.1e-12 48.1 0.0 2.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain WSD PF15613.6 GBG73990.1 - 1.9e-10 41.1 0.3 1.9e-10 41.1 0.3 3.8 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 GBG73990.1 - 2.5e-06 26.9 0.0 6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Homeobox_KN PF05920.11 GBG73990.1 - 0.0017 18.2 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain RT_RNaseH_2 PF17919.1 GBG73991.1 - 2.4e-34 117.3 0.0 4.3e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG73991.1 - 1.7e-22 79.6 0.0 3.2e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PAN_1 PF00024.26 GBG73992.1 - 0.0011 18.9 0.6 0.0019 18.1 0.6 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 GBG73992.1 - 0.017 15.0 1.4 0.03 14.2 1.4 1.4 1 0 0 1 1 1 0 PAN domain RuvX PF03652.15 GBG73995.1 - 3.8e-19 69.4 0.8 6.6e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction resolvase YjeF_N PF03853.15 GBG73995.1 - 0.021 14.7 0.2 2.5 8.0 0.3 2.5 2 0 0 2 2 2 0 YjeF-related protein N-terminus Pro_dh-DNA_bdg PF14850.6 GBG73995.1 - 0.074 13.6 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 DNA-binding domain of Proline dehydrogenase DUF1471 PF07338.13 GBG73995.1 - 3.9 7.5 11.7 2.1 8.4 0.9 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1471) PEPCK_ATP PF01293.20 GBG73996.1 - 2e-211 702.7 0.0 2.4e-211 702.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF4529 PF15032.6 GBG73996.1 - 0.061 12.4 0.2 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) WDCP PF15390.6 GBG73997.1 - 0.24 9.7 2.3 0.29 9.5 2.3 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DDRGK PF09756.9 GBG73997.1 - 5.2 6.6 8.9 6.9 6.2 8.9 1.2 1 0 0 1 1 1 0 DDRGK domain DUF4288 PF14119.6 GBG73997.1 - 5.3 7.5 6.6 15 6.1 6.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4288) WRW PF10206.9 GBG73998.1 - 0.037 14.4 0.1 0.068 13.5 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f PPDFL PF15060.6 GBG73998.1 - 0.52 10.9 3.6 4.6 7.8 0.6 2.7 2 0 0 2 2 2 0 Differentiation and proliferation regulator Hydrolase_4 PF12146.8 GBG73999.1 - 2e-14 53.5 0.0 6.8e-13 48.4 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG73999.1 - 3.5e-06 26.9 0.1 7.6e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 GBG73999.1 - 0.065 11.9 0.0 0.2 10.3 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) PhoPQ_related PF10142.9 GBG73999.1 - 0.3 9.7 0.1 0.45 9.1 0.1 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Integrase_H2C2 PF17921.1 GBG74000.1 - 1.5e-13 50.6 0.3 2.8e-13 49.8 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_4 PF13359.6 GBG74001.1 - 3.4e-20 72.3 0.0 8.5e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74001.1 - 1e-12 48.1 0.0 3e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Plant transposon protein ZapB PF06005.12 GBG74001.1 - 9.1e-05 22.8 1.0 0.01 16.3 0.6 2.5 2 0 0 2 2 2 1 Cell division protein ZapB NEMO PF11577.8 GBG74001.1 - 0.00059 19.8 0.7 0.0096 15.9 1.1 2.3 2 0 0 2 2 2 1 NF-kappa-B essential modulator NEMO BicD PF09730.9 GBG74001.1 - 0.01 14.3 1.3 0.016 13.6 1.3 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D ADIP PF11559.8 GBG74001.1 - 0.014 15.5 1.6 0.014 15.5 1.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HofP PF10748.9 GBG74001.1 - 0.014 14.9 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 DNA utilization proteins HofP CCDC106 PF15794.5 GBG74001.1 - 0.071 12.8 2.3 0.098 12.4 1.4 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 Myosin_tail_1 PF01576.19 GBG74001.1 - 0.091 10.6 3.5 0.15 9.9 3.5 1.2 1 0 0 1 1 1 0 Myosin tail DUF4838 PF16126.5 GBG74001.1 - 0.096 12.0 0.5 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) THOC7 PF05615.13 GBG74001.1 - 0.23 11.8 2.1 0.98 9.7 0.3 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 NPV_P10 PF05531.12 GBG74001.1 - 0.4 11.2 1.0 7.4 7.1 0.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 GBG74001.1 - 0.66 9.8 2.8 0.92 9.3 0.3 2.2 2 0 0 2 2 2 0 Septum formation initiator Phage_GP20 PF06810.11 GBG74001.1 - 1.6 8.6 3.8 2.7 7.8 0.5 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Prefoldin PF02996.17 GBG74001.1 - 1.9 8.4 5.0 1.7 8.6 2.3 2.1 2 0 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 GBG74001.1 - 3.2 7.8 9.9 0.8 9.8 1.5 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 GBG74001.1 - 5.9 7.1 9.1 33 4.7 5.9 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 RVT_1 PF00078.27 GBG74002.1 - 9.5e-26 90.7 0.0 1.6e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74002.1 - 1.1e-24 86.3 0.0 2.8e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74002.1 - 2.7e-23 82.3 0.0 5.9e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG74002.1 - 2.2e-05 24.3 0.0 3.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG74002.1 - 5.2e-05 23.7 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74002.1 - 9.1e-05 23.0 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG74002.1 - 0.00084 19.5 0.1 0.0021 18.2 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG74002.1 - 0.00092 19.0 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG74004.1 - 4.5e-29 100.8 0.1 5.3e-28 97.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74004.1 - 4e-28 97.4 0.0 3.7e-27 94.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74004.1 - 2.1e-26 92.8 0.1 4.5e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74004.1 - 4.2e-18 65.2 0.6 4.2e-18 65.2 0.6 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG74004.1 - 3.8e-14 52.9 0.0 1.3e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG74004.1 - 5.9e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74004.1 - 1.2e-05 25.9 0.0 2.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74004.1 - 0.0011 19.5 0.0 0.0043 17.6 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG74004.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG74004.1 - 0.0067 16.6 0.1 0.023 14.9 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG74004.1 - 0.04 13.7 0.0 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease Chromo PF00385.24 GBG74004.1 - 0.062 13.2 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain SOG2 PF10428.9 GBG74005.1 - 5.4 6.1 13.3 7.1 5.7 13.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RT_RNaseH_2 PF17919.1 GBG74006.1 - 1.4e-32 111.7 0.1 2.9e-32 110.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74006.1 - 1.3e-29 102.6 0.1 2.4e-29 101.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74006.1 - 1.3e-29 103.3 0.0 2.5e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74006.1 - 1.5e-18 66.7 0.3 5.4e-18 64.9 0.3 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74006.1 - 4.9e-09 36.4 0.6 0.0012 19.0 0.1 3.2 3 0 0 3 3 3 2 Integrase core domain zf-H2C2 PF09337.10 GBG74006.1 - 0.11 12.7 0.0 0.36 11.1 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Pkinase_Tyr PF07714.17 GBG74007.1 - 2.6e-46 158.0 0.0 5.9e-46 156.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG74007.1 - 1.1e-45 156.1 0.0 2.4e-45 155.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH PF17917.1 GBG74007.1 - 3.4e-29 101.2 0.0 9.7e-29 99.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74007.1 - 5.9e-29 100.1 0.0 2e-28 98.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74007.1 - 1.6e-25 89.9 0.1 3.6e-25 88.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74007.1 - 1e-09 38.3 0.0 2.9e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain ABC1 PF03109.16 GBG74007.1 - 0.0059 16.8 0.0 0.03 14.5 0.0 2.2 2 0 0 2 2 2 1 ABC1 family zf-H2C2 PF09337.10 GBG74007.1 - 0.093 13.0 0.0 0.35 11.1 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger APH PF01636.23 GBG74007.1 - 0.099 12.5 0.0 0.099 12.5 0.0 3.4 3 1 1 4 4 4 0 Phosphotransferase enzyme family REV PF00424.18 GBG74007.1 - 1.2 9.2 3.9 1.4 9.0 0.2 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) UPRTase PF14681.6 GBG74009.1 - 1.7e-59 200.8 0.0 2.1e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GBG74009.1 - 3.7e-10 39.5 0.0 6.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GGGtGRT PF14057.6 GBG74009.1 - 0.093 11.7 0.2 0.14 11.1 0.2 1.1 1 0 0 1 1 1 0 GGGtGRT protein CCDC154 PF15450.6 GBG74010.1 - 0.0061 15.2 14.2 0.059 11.9 3.0 2.1 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 154 Trimer_CC PF08954.11 GBG74010.1 - 0.0076 15.8 1.2 0.0076 15.8 1.2 4.4 6 0 0 6 6 6 1 Trimerisation motif Spc7 PF08317.11 GBG74010.1 - 0.02 13.8 14.1 0.045 12.6 4.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 GBG74010.1 - 0.067 13.3 0.6 0.067 13.3 0.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FTA4 PF13093.6 GBG74010.1 - 0.19 11.6 5.8 0.31 10.9 5.5 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Activator-TraM PF11657.8 GBG74010.1 - 0.29 11.0 3.3 0.22 11.4 0.2 2.2 1 1 1 2 2 2 0 Transcriptional activator TraM Uso1_p115_C PF04871.13 GBG74010.1 - 0.4 11.1 15.2 2.7e+02 1.9 15.2 2.7 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 GBG74010.1 - 0.83 10.3 9.9 1.9 9.2 1.7 2.7 2 1 0 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 GBG74010.1 - 1.3 9.3 19.5 1.8 8.8 2.3 3.3 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding HAUS-augmin3 PF14932.6 GBG74010.1 - 1.3 8.5 14.2 0.062 12.9 6.2 2.1 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 XhlA PF10779.9 GBG74010.1 - 2.5 8.4 7.4 2 8.7 1.7 2.6 2 0 0 2 2 2 0 Haemolysin XhlA APG6_N PF17675.1 GBG74010.1 - 2.9 8.4 25.5 78 3.8 5.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 GBG74010.1 - 3.5 6.9 10.7 9.4 5.5 10.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 GBG74010.1 - 4.2 7.6 13.5 0.65 10.3 3.5 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 GBG74010.1 - 5.1 7.2 18.7 8.9 6.4 5.7 3.4 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 GBG74010.1 - 6.1 6.0 5.4 4.4 6.5 1.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein RVT_1 PF00078.27 GBG74012.1 - 3.4e-31 108.5 0.0 5.2e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG74015.1 - 1.7e-07 31.8 0.0 3.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74015.1 - 3.7e-07 30.6 0.0 9.4e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74015.1 - 6e-07 29.3 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74015.1 - 4.8e-05 23.2 0.0 7.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease SUI1 PF01253.22 GBG74016.1 - 2e-19 69.9 0.1 4.5e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Bse634I PF07832.11 GBG74016.1 - 0.17 11.2 0.0 2.3 7.5 0.0 2.0 2 0 0 2 2 2 0 Cfr10I/Bse634I restriction endonuclease RVT_1 PF00078.27 GBG74017.1 - 5.9e-17 61.9 0.0 1.5e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG74017.1 - 1.6e-06 28.7 0.0 8.5e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74017.1 - 5.2e-06 26.9 0.0 1.7e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74017.1 - 8.7e-06 25.5 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG74017.1 - 0.0027 18.0 0.4 0.012 15.8 0.4 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG74017.1 - 0.0048 16.7 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_3 PF13917.6 GBG74017.1 - 0.073 13.0 1.4 0.2 11.6 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Borrelia_REV PF03978.13 GBG74017.1 - 0.92 9.4 3.1 0.28 11.1 0.1 1.7 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein RVT_1 PF00078.27 GBG74018.1 - 8.2e-28 97.4 0.1 1.4e-27 96.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RINGv PF12906.7 GBG74019.1 - 2e-16 59.8 7.3 4.8e-16 58.6 7.3 1.7 1 0 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 GBG74019.1 - 0.0068 16.4 2.6 0.018 15.1 2.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 GBG74019.1 - 0.018 15.4 7.2 0.048 14.0 7.2 1.8 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 GBG74019.1 - 0.39 10.9 3.6 1.1 9.5 3.6 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-rbx1 PF12678.7 GBG74019.1 - 2.5 8.5 4.4 6.9 7.0 4.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 GBG74019.1 - 5 7.5 7.2 20 5.6 7.2 2.1 1 0 0 1 1 1 0 RING-like domain Chorion_3 PF05387.11 GBG74020.1 - 1.3 8.6 4.7 15 5.1 1.5 2.0 2 0 0 2 2 2 0 Chorion family 3 Synaphin PF05835.12 GBG74020.1 - 3.1 8.1 14.6 0.24 11.7 1.7 2.2 2 0 0 2 2 2 0 Synaphin protein DUF659 PF04937.15 GBG74021.1 - 1e-18 67.6 0.0 2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF1640 PF07798.11 GBG74021.1 - 0.45 10.5 2.3 0.82 9.7 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Band_7 PF01145.25 GBG74022.1 - 7.8e-14 52.1 10.8 2e-13 50.8 10.8 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family Imm21 PF15589.6 GBG74023.1 - 0.14 12.2 0.1 11 6.0 0.0 2.1 1 1 1 2 2 2 0 Immunity protein 21 PBP3 PF18056.1 GBG74025.1 - 0.0041 17.2 0.3 1.1 9.5 0.0 2.7 3 0 0 3 3 3 2 Penicillin Binding Protein 3 Domain Asp_protease_2 PF13650.6 GBG74025.1 - 0.064 13.9 0.0 0.31 11.7 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease DUF913 PF06025.12 GBG74025.1 - 0.082 11.9 1.0 0.12 11.4 1.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4968 PF16338.5 GBG74025.1 - 0.11 12.8 0.3 3 8.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4968) gag-asp_proteas PF13975.6 GBG74034.1 - 7.4e-06 26.4 0.0 2.6e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74034.1 - 7.6e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74034.1 - 9.6e-06 26.2 0.0 4.3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG74034.1 - 0.00025 20.8 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Caudo_TAP PF02413.17 GBG74034.1 - 0.24 11.6 2.2 0.51 10.5 2.2 1.5 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK LPP PF04728.13 GBG74034.1 - 8.8 6.8 10.5 4.3 7.8 0.2 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Retrotrans_gag PF03732.17 GBG74035.1 - 0.038 14.3 0.1 0.088 13.1 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein PHO4 PF01384.20 GBG74036.1 - 2.1e-110 369.0 16.5 2.7e-110 368.6 16.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family LMBR1 PF04791.16 GBG74036.1 - 0.0012 17.8 0.7 0.01 14.8 0.0 2.3 2 0 0 2 2 2 1 LMBR1-like membrane protein Oxidored_molyb PF00174.19 GBG74037.1 - 0.19 11.4 1.7 0.21 11.2 0.3 1.8 2 0 0 2 2 2 0 Oxidoreductase molybdopterin binding domain DUF659 PF04937.15 GBG74039.1 - 1.1e-11 44.9 0.0 1.7e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4373 PF14297.6 GBG74039.1 - 0.11 13.3 0.1 0.22 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) zf-FCS PF06467.14 GBG74039.1 - 0.23 11.4 0.5 0.42 10.6 0.5 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DivIC PF04977.15 GBG74040.1 - 0.0013 18.4 0.9 0.0013 18.4 0.9 3.3 3 0 0 3 3 3 1 Septum formation initiator ZapB PF06005.12 GBG74040.1 - 0.006 17.0 5.3 0.006 17.0 5.3 4.7 4 1 0 4 4 4 1 Cell division protein ZapB Nup54 PF13874.6 GBG74040.1 - 0.0099 16.0 5.7 0.05 13.7 3.4 2.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Seryl_tRNA_N PF02403.22 GBG74040.1 - 0.01 16.1 2.7 0.01 16.1 2.7 3.9 4 2 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF5339 PF17274.2 GBG74040.1 - 0.011 16.6 4.0 1.5 9.7 1.4 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5339) TMF_DNA_bd PF12329.8 GBG74040.1 - 0.016 15.2 9.1 0.016 15.2 9.1 4.3 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.18 GBG74040.1 - 0.031 14.5 1.1 0.031 14.5 1.1 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper BLOC1_2 PF10046.9 GBG74040.1 - 0.41 11.0 6.2 9.2 6.6 2.1 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 GBG74040.1 - 0.92 9.6 6.4 1.6 8.8 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 GBG74040.1 - 4.3 7.5 28.3 0.022 15.0 3.1 3.6 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) SDA1 PF05285.12 GBG74041.1 - 0.27 10.6 45.5 0.29 10.5 45.5 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 GBG74041.1 - 0.69 8.8 3.8 0.87 8.5 3.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 GBG74041.1 - 8.3 5.1 16.3 7.8 5.1 16.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RVT_1 PF00078.27 GBG74042.1 - 9.2e-30 103.8 0.0 1.4e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHO4 PF01384.20 GBG74043.1 - 1.3e-110 369.6 18.2 1.7e-110 369.2 18.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family LMBR1 PF04791.16 GBG74043.1 - 0.0011 18.0 0.3 0.06 12.3 0.0 2.3 2 0 0 2 2 2 2 LMBR1-like membrane protein DUF4225 PF13988.6 GBG74043.1 - 0.38 10.3 1.3 0.88 9.1 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) PHO4 PF01384.20 GBG74044.1 - 3.4e-110 368.3 18.8 4.2e-110 368.0 18.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family LMBR1 PF04791.16 GBG74044.1 - 0.062 12.2 0.0 0.062 12.2 0.0 2.7 3 0 0 3 3 3 0 LMBR1-like membrane protein CCSAP PF15748.5 GBG74045.1 - 0.075 13.2 22.5 0.091 12.9 22.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SLC12 PF03522.15 GBG74045.1 - 1.2 8.0 16.7 1.5 7.8 16.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SDA1 PF05285.12 GBG74045.1 - 1.8 7.9 50.4 2.2 7.6 50.4 1.1 1 0 0 1 1 1 0 SDA1 Endostatin PF06482.11 GBG74045.1 - 3.8 6.9 6.5 4.4 6.7 6.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin MDM1 PF15501.6 GBG74045.1 - 4.3 6.4 29.2 6.1 5.9 29.2 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 NARP1 PF12569.8 GBG74045.1 - 4.4 6.1 18.5 5.2 5.9 18.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 GBG74045.1 - 4.8 5.9 25.1 5.8 5.6 25.1 1.0 1 0 0 1 1 1 0 Presenilin ARL6IP6 PF15062.6 GBG74046.1 - 0.07 13.3 0.0 0.079 13.1 0.0 1.1 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix DAP PF15228.6 GBG74049.1 - 0.62 11.3 3.4 0.71 11.1 3.4 1.1 1 0 0 1 1 1 0 Death-associated protein DNA_pol_delta_4 PF04081.13 GBG74049.1 - 2.6 8.4 12.7 2.9 8.2 12.7 1.0 1 0 0 1 1 1 0 DNA polymerase delta, subunit 4 DDE_Tnp_4 PF13359.6 GBG74051.1 - 6.6e-07 29.1 0.0 1.7e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease GHMP_kinases_N PF00288.26 GBG74052.1 - 0.015 15.5 9.4 0.042 14.1 9.4 1.8 1 0 0 1 1 1 0 GHMP kinases N terminal domain RVT_1 PF00078.27 GBG74054.1 - 4.3e-43 147.4 0.3 7e-22 78.0 0.0 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG74054.1 - 0.0012 19.1 0.3 0.01 16.1 0.0 2.8 3 1 0 3 3 3 1 Retrotransposon gag protein APG17 PF04108.12 GBG74054.1 - 0.016 14.3 0.1 0.25 10.4 0.0 2.6 3 1 0 3 3 3 0 Autophagy protein Apg17 Trans_reg_C PF00486.28 GBG74054.1 - 0.19 11.8 0.7 22 5.2 0.1 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal TFIIA PF03153.13 GBG74055.1 - 7.2 6.5 13.0 11 5.9 13.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LAP1C PF05609.12 GBG74057.1 - 0.046 12.8 0.2 0.046 12.8 0.2 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Toprim_N PF08275.11 GBG74059.1 - 1.5e-07 31.5 17.6 16 5.6 0.0 13.3 6 5 7 14 14 14 1 DNA primase catalytic core, N-terminal domain PapC_C PF13953.6 GBG74059.1 - 2e-06 27.5 64.8 3.1 7.7 0.8 15.7 2 2 17 20 20 20 12 PapC C-terminal domain RTA1 PF04479.13 GBG74059.1 - 0.00032 20.4 26.4 65 3.0 0.0 13.0 8 5 7 15 15 15 0 RTA1 like protein Swi6_N PF18530.1 GBG74065.1 - 0.0063 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Swi6 N-terminal domain rve PF00665.26 GBG74066.1 - 1.5e-16 60.6 0.0 4.1e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG74066.1 - 0.019 14.7 0.3 0.068 13.0 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain RNA_pol_Rpb2_1 PF04563.15 GBG74067.1 - 1.5e-40 138.8 0.0 2.3e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit ArfGap PF01412.18 GBG74068.1 - 1.7e-34 118.4 0.0 3.1e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Nuc_sug_transp PF04142.15 GBG74070.1 - 1.1e-12 47.7 8.8 3.5e-12 46.1 8.8 1.9 1 0 0 1 1 1 1 Nucleotide-sugar transporter Serinc PF03348.15 GBG74070.1 - 0.0038 16.2 2.0 0.0038 16.2 2.0 3.6 1 1 2 3 3 3 1 Serine incorporator (Serinc) BSMAP PF12280.8 GBG74070.1 - 0.38 10.9 0.0 0.38 10.9 0.0 4.2 1 1 2 3 3 3 0 Brain specific membrane anchored protein EamA PF00892.20 GBG74070.1 - 8.9 6.5 15.6 0.18 12.0 7.8 2.0 2 1 0 2 2 2 0 EamA-like transporter family Nuc_sug_transp PF04142.15 GBG74072.1 - 1.2e-11 44.4 3.0 1.4e-11 44.2 3.0 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter Nicastrin PF05450.15 GBG74072.1 - 0.036 13.5 0.2 0.11 11.9 0.2 1.8 1 1 1 2 2 2 0 Nicastrin DUF2269 PF10027.9 GBG74072.1 - 0.077 13.1 0.2 0.093 12.8 0.2 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF5455 PF17537.2 GBG74072.1 - 0.1 13.0 2.6 0.14 12.6 2.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5455) gag-asp_proteas PF13975.6 GBG74073.1 - 7.8e-05 23.2 0.1 0.00025 21.5 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74073.1 - 0.00073 20.1 0.5 0.0047 17.5 0.1 2.5 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG74073.1 - 0.0034 17.1 0.1 0.0069 16.1 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74073.1 - 0.015 15.1 0.2 0.028 14.2 0.2 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4881 PF16222.5 GBG74073.1 - 0.038 13.8 0.1 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4881) zf-CCHC PF00098.23 GBG74073.1 - 0.091 12.9 2.1 0.17 12.0 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle UCH PF00443.29 GBG74074.1 - 2.1e-34 119.2 0.0 1.4e-30 106.7 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG74074.1 - 3.3e-22 79.5 0.3 1.1e-14 54.8 0.0 3.2 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 GBG74074.1 - 0.00077 19.2 1.9 0.0043 16.9 1.9 2.4 1 0 0 1 1 1 1 Ubiquitin interaction motif zf-FPG_IleRS PF06827.14 GBG74074.1 - 9.2 6.2 11.2 11 6.0 0.5 3.7 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF659 PF04937.15 GBG74075.1 - 1.4e-38 132.2 0.2 3e-38 131.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Utp14 PF04615.13 GBG74076.1 - 0.014 14.0 12.4 0.014 14.0 12.4 1.2 1 0 0 1 1 1 0 Utp14 protein DUF2271 PF10029.9 GBG74076.1 - 0.021 14.5 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) SOG2 PF10428.9 GBG74076.1 - 0.05 12.8 13.5 0.065 12.4 13.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SDA1 PF05285.12 GBG74076.1 - 0.25 10.7 11.7 0.4 10.1 11.7 1.3 1 0 0 1 1 1 0 SDA1 LMBR1 PF04791.16 GBG74076.1 - 0.78 8.6 4.6 0.82 8.5 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Dapper PF15268.6 GBG74076.1 - 1.1 8.0 12.5 1.6 7.5 12.5 1.2 1 0 0 1 1 1 0 Dapper Rxt3 PF08642.10 GBG74076.1 - 2.4 8.9 11.8 12 6.7 0.0 2.9 1 1 1 2 2 2 0 Histone deacetylation protein Rxt3 Zip PF02535.22 GBG74076.1 - 3.8 6.6 8.3 5.9 6.0 8.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 GBG74076.1 - 4.9 5.2 17.1 6.9 4.8 17.1 1.2 1 0 0 1 1 1 0 Nop14-like family Gelsolin PF00626.22 GBG74077.1 - 9e-78 256.2 0.1 2.8e-16 59.2 0.0 6.4 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.19 GBG74077.1 - 1.2e-13 50.9 8.1 2.4e-13 49.9 8.1 1.6 1 0 0 1 1 1 1 Villin headpiece domain Bowman-Birk_leg PF00228.20 GBG74077.1 - 0.24 11.8 0.7 9.6 6.7 0.1 2.9 3 0 0 3 3 3 0 Bowman-Birk serine protease inhibitor family DUF348 PF03990.14 GBG74078.1 - 0.099 12.4 0.9 0.22 11.3 0.0 2.1 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain Branch PF02485.21 GBG74080.1 - 1.4e-56 191.7 0.0 2.9e-56 190.7 0.0 1.6 1 0 0 1 1 1 1 Core-2/I-Branching enzyme RT_RNaseH_2 PF17919.1 GBG74080.1 - 4e-53 177.6 0.0 9.5e-28 96.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74080.1 - 6.8e-52 174.2 1.6 9.6e-28 96.6 0.1 3.3 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74080.1 - 2.9e-26 92.4 0.4 1.8e-21 76.7 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG74080.1 - 0.0057 16.5 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG74080.1 - 0.073 13.4 1.3 0.36 11.1 0.1 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein SDA1 PF05285.12 GBG74081.1 - 0.018 14.5 5.9 0.023 14.2 5.9 1.1 1 0 0 1 1 1 0 SDA1 PNISR PF15996.5 GBG74081.1 - 0.073 13.3 0.9 0.095 13.0 0.9 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CybS PF05328.12 GBG74081.1 - 0.13 12.0 2.5 0.29 10.8 2.5 1.6 1 1 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit RVT_1 PF00078.27 GBG74082.1 - 5.1e-26 91.6 0.0 1.7e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74082.1 - 6.8e-17 61.3 0.2 1.7e-16 60.1 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG74082.1 - 2.1e-15 56.9 0.0 8.3e-15 55.0 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Lipase_3 PF01764.25 GBG74082.1 - 1.3e-12 47.8 0.0 3.2e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) RT_RNaseH_2 PF17919.1 GBG74082.1 - 5.4e-10 39.2 0.0 1.2e-08 34.9 0.0 2.8 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase DPBB_1 PF03330.18 GBG74084.1 - 4.4e-14 52.5 0.3 4.4e-14 52.5 0.3 1.7 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG74084.1 - 1.7e-11 44.0 0.0 2.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen BUD22 PF09073.10 GBG74085.1 - 0.0024 17.3 19.6 0.0034 16.8 19.6 1.1 1 0 0 1 1 1 1 BUD22 BSP_II PF05432.11 GBG74085.1 - 0.024 14.3 22.4 0.034 13.8 22.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Mitofilin PF09731.9 GBG74085.1 - 0.096 11.5 11.1 0.12 11.1 11.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC45 PF02724.14 GBG74085.1 - 0.33 9.2 14.9 0.42 8.8 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG74085.1 - 0.43 10.0 20.8 0.6 9.5 20.8 1.2 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 GBG74085.1 - 0.61 10.4 22.9 1.2 9.4 22.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GBG74085.1 - 0.63 8.2 21.6 0.82 7.8 21.6 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG74085.1 - 0.89 8.3 8.5 1.2 7.9 8.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GBG74085.1 - 3.4 6.3 11.1 4.7 5.9 11.1 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 GBG74085.1 - 5.8 4.9 9.0 7.3 4.6 9.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDE_Tnp_4 PF13359.6 GBG74086.1 - 7.6e-12 45.2 0.0 1.5e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74086.1 - 0.0031 17.2 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG74086.1 - 6.2 6.4 7.7 0.4 10.3 0.4 2.6 4 0 0 4 4 4 0 Transposase DDE domain Asp_protease_2 PF13650.6 GBG74088.1 - 0.0018 18.9 0.0 0.0034 18.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG74089.1 - 7.1e-28 97.6 0.0 1.2e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74089.1 - 1.1e-16 60.6 0.0 2.4e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG74089.1 - 7e-13 48.3 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG74089.1 - 3.9e-05 23.9 0.0 7.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pollen_allerg_1 PF01357.21 GBG74093.1 - 8.7e-14 51.3 0.1 1.5e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.18 GBG74093.1 - 2.4e-13 50.1 0.2 2.4e-13 50.1 0.2 1.8 2 0 0 2 2 2 1 Lytic transglycolase RT_RNaseH_2 PF17919.1 GBG74095.1 - 8e-27 93.2 0.0 1.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74095.1 - 3.5e-21 75.4 0.0 6.8e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74095.1 - 1.7e-06 27.7 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG74095.1 - 0.17 10.1 8.6 0.21 9.8 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG74095.1 - 0.81 9.0 11.6 1.1 8.6 11.6 1.1 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 GBG74095.1 - 2.6 8.3 14.4 4.2 7.7 14.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG74095.1 - 8.1 4.6 10.8 11 4.1 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Na_trans_assoc PF06512.13 GBG74096.1 - 0.0074 16.6 3.8 0.0074 16.6 3.8 1.1 1 0 0 1 1 1 1 Sodium ion transport-associated PTPRCAP PF15713.5 GBG74096.1 - 2.6 8.4 15.7 3.5 7.9 15.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SspB PF04386.13 GBG74096.1 - 5.5 6.9 9.1 7.5 6.4 9.1 1.1 1 0 0 1 1 1 0 Stringent starvation protein B CDC45 PF02724.14 GBG74096.1 - 7 4.8 15.9 8.6 4.5 15.9 1.0 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC PF00098.23 GBG74097.1 - 0.00028 20.8 1.4 0.00065 19.7 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF4280 PF14107.6 GBG74097.1 - 0.03 15.1 0.0 0.09 13.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4280) zf-CCHC_5 PF14787.6 GBG74097.1 - 0.046 13.4 1.9 0.099 12.4 1.9 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RNase_HII PF01351.18 GBG74099.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Ribonuclease HII DPBB_1 PF03330.18 GBG74100.1 - 1e-13 51.3 0.4 1e-13 51.3 0.4 2.0 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG74100.1 - 5.7e-12 45.5 0.1 1e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 Pollen allergen Hid1 PF12722.7 GBG74101.1 - 0.11 10.6 28.0 0.12 10.4 28.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BUD22 PF09073.10 GBG74101.1 - 0.13 11.6 59.6 0.17 11.2 59.6 1.1 1 0 0 1 1 1 0 BUD22 Ribosomal_60s PF00428.19 GBG74102.1 - 0.2 12.3 2.3 0.76 10.4 2.2 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein zinc-ribbons_6 PF07191.12 GBG74103.1 - 0.56 10.2 4.5 1.4 9.0 4.5 1.6 1 0 0 1 1 1 0 zinc-ribbons RVT_1 PF00078.27 GBG74104.1 - 1.7e-28 99.6 0.2 2.6e-28 99.1 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG74104.1 - 0.0021 17.5 30.4 0.003 17.0 30.4 1.2 1 0 0 1 1 1 1 SDA1 Orf78 PF06024.12 GBG74104.1 - 0.046 14.0 5.5 0.19 12.1 5.5 2.1 1 1 0 1 1 1 0 Orf78 (ac78) Nop14 PF04147.12 GBG74104.1 - 0.13 10.4 31.8 0.17 10.1 31.8 1.1 1 0 0 1 1 1 0 Nop14-like family PNISR PF15996.5 GBG74104.1 - 0.34 11.1 4.5 0.52 10.6 4.5 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF913 PF06025.12 GBG74104.1 - 0.63 9.0 4.6 0.91 8.4 4.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 GBG74104.1 - 0.83 8.4 9.2 1.3 7.8 9.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mpp10 PF04006.12 GBG74104.1 - 1.3 7.4 21.3 1.8 6.9 21.3 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 GBG74104.1 - 1.3 7.7 10.7 1.7 7.3 10.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.11 GBG74104.1 - 1.3 8.5 25.0 2.1 7.9 25.0 1.3 1 0 0 1 1 1 0 PPP4R2 Nop25 PF09805.9 GBG74104.1 - 3.1 8.3 10.7 5.9 7.4 10.7 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) BUD22 PF09073.10 GBG74104.1 - 3.1 7.0 27.8 4.1 6.7 27.8 1.1 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.16 GBG74106.1 - 8.1e-17 61.2 30.3 7e-13 48.2 14.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily SPX PF03105.19 GBG74106.1 - 7.1e-09 36.1 30.4 3.5e-08 33.8 0.7 4.7 3 1 0 3 3 3 1 SPX domain PilS PF08805.11 GBG74108.1 - 0.17 11.7 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 PilS N terminal Sigma70_r4 PF04545.16 GBG74109.1 - 5.4e-17 61.0 0.4 1.2e-16 60.0 0.4 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 GBG74109.1 - 0.011 15.3 0.2 0.049 13.2 0.2 2.0 1 1 0 1 1 1 0 Bacterial regulatory proteins, luxR family LBR_tudor PF09465.10 GBG74109.1 - 0.035 13.9 0.1 0.09 12.6 0.1 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain ADH_N_assoc PF13823.6 GBG74109.1 - 0.18 11.8 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated RVT_1 PF00078.27 GBG74110.1 - 2.4e-32 112.3 0.1 3.9e-32 111.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74110.1 - 2.6e-24 85.5 0.2 4.9e-24 84.6 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74110.1 - 1.5e-16 60.3 0.1 3.1e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74110.1 - 4.7e-16 59.1 0.0 1.2e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG74110.1 - 8.4e-14 51.4 0.0 1.9e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain STAT1_TAZ2bind PF12162.8 GBG74110.1 - 0.05 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Sigma70_r2 PF04542.14 GBG74111.1 - 4.5e-19 68.0 0.1 4.5e-19 68.0 0.1 1.9 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 GBG74111.1 - 1.5e-05 25.0 4.5 0.00026 21.0 0.5 2.9 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 GBG74111.1 - 0.0003 20.7 0.1 0.0003 20.7 0.1 1.9 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 CDC45 PF02724.14 GBG74111.1 - 0.24 9.7 6.7 0.38 9.0 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_r2 PF04542.14 GBG74112.1 - 4.4e-19 68.0 0.1 4.4e-19 68.0 0.1 1.9 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 GBG74112.1 - 9.9e-06 25.6 5.6 0.00025 21.1 0.5 2.9 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 GBG74112.1 - 0.00029 20.8 0.1 0.00029 20.8 0.1 1.9 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 CDC45 PF02724.14 GBG74112.1 - 0.23 9.7 6.7 0.37 9.0 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SQHop_cyclase_N PF13249.6 GBG74114.1 - 7.1e-21 74.6 0.1 3.1e-20 72.5 0.1 1.8 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 GBG74114.1 - 8.8e-18 63.7 0.1 6.1e-12 45.1 0.0 2.7 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GBG74114.1 - 3.7e-06 26.3 0.1 1.1e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_C PF13243.6 GBG74115.1 - 8.1e-48 163.1 0.1 1e-47 162.8 0.1 1.1 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 GBG74115.1 - 8.4e-18 63.8 2.9 2.8e-07 30.1 1.4 4.1 4 0 0 4 4 4 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 GBG74115.1 - 0.00011 21.5 0.0 0.059 12.4 0.0 3.9 4 1 0 4 4 4 1 Squalene-hopene cyclase N-terminal domain Pec_lyase PF09492.10 GBG74115.1 - 0.0018 17.7 0.0 1 8.7 0.0 2.8 3 0 0 3 3 3 2 Pectic acid lyase Chromo PF00385.24 GBG74116.1 - 1.3e-12 47.4 0.0 2.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-C2H2 PF00096.26 GBG74118.1 - 2.8e-05 24.3 12.7 0.019 15.4 0.3 4.2 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 GBG74118.1 - 0.00048 20.1 5.1 0.12 12.4 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GBG74118.1 - 0.00055 20.1 0.2 0.00055 20.1 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GBG74118.1 - 0.0022 18.3 0.1 0.021 15.2 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GBG74118.1 - 0.0077 17.0 10.6 0.58 11.2 0.2 4.4 3 0 0 3 3 3 2 C2H2-type zinc finger DDE_Tnp_4 PF13359.6 GBG74119.1 - 0.091 12.4 0.4 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 GBG74120.1 - 8.7e-27 93.7 0.0 1.6e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74120.1 - 4.1e-09 36.3 0.0 6.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG74120.1 - 0.028 14.1 0.1 4.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain CENP-F_leu_zip PF10473.9 GBG74121.1 - 0.00056 20.0 14.8 0.00056 20.0 14.8 7.1 2 2 4 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 GBG74121.1 - 0.0012 16.5 42.6 0.0012 16.5 42.6 3.4 1 1 1 3 3 3 1 Protein of unknown function (DUF3584) ZapB PF06005.12 GBG74121.1 - 0.0037 17.7 5.4 0.0037 17.7 5.4 10.0 2 2 5 8 8 8 2 Cell division protein ZapB CENP-F_leu_zip PF10473.9 GBG74122.1 - 0.00052 20.0 14.8 0.00052 20.0 14.8 6.7 2 2 4 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 GBG74122.1 - 0.0026 18.1 5.0 0.0026 18.1 5.0 10.0 2 2 5 8 8 8 2 Cell division protein ZapB Golgin_A5 PF09787.9 GBG74122.1 - 0.005 16.4 31.4 0.005 16.4 31.4 5.7 1 1 5 6 6 6 1 Golgin subfamily A member 5 UPF0242 PF06785.11 GBG74122.1 - 0.014 15.5 38.3 0.014 15.5 38.3 5.7 2 2 3 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus RVT_1 PF00078.27 GBG74123.1 - 1.7e-08 34.3 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG74123.1 - 0.98 8.8 21.9 1.3 8.4 21.9 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG74123.1 - 1.6 8.0 23.6 2.2 7.5 23.6 1.1 1 0 0 1 1 1 0 BUD22 DUF659 PF04937.15 GBG74124.1 - 7.1e-21 74.7 0.0 1.3e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG74124.1 - 8.9e-06 25.4 0.1 2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG74128.1 - 8.5e-22 77.1 0.0 2.4e-21 75.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74128.1 - 5.8e-19 68.5 0.5 4.7e-11 42.6 0.1 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74128.1 - 2.1e-11 44.0 0.0 5.9e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74128.1 - 4.3e-08 33.7 0.0 1.4e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74128.1 - 1.1e-07 32.4 0.1 6.3e-07 29.9 0.0 2.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74128.1 - 3.8e-05 23.5 0.0 8.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74128.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74128.1 - 0.0038 17.5 0.0 0.0038 17.5 0.0 3.7 4 0 0 4 4 4 1 Retrotransposon gag protein SPARC_Ca_bdg PF10591.9 GBG74128.1 - 0.61 10.4 2.4 1.4 9.3 0.8 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region RVT_1 PF00078.27 GBG74130.1 - 2.6e-30 105.6 0.0 5e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74130.1 - 1.7e-28 98.6 0.0 5e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74130.1 - 1.8e-28 98.9 0.2 5.2e-28 97.4 0.2 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG74130.1 - 1.2e-20 74.0 0.0 3.8e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DegQ PF08181.11 GBG74130.1 - 1.1 9.3 6.7 8.5 6.6 3.1 2.7 2 0 0 2 2 2 0 DegQ (SacQ) family RVT_1 PF00078.27 GBG74131.1 - 2.4e-28 99.2 0.0 4.2e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74131.1 - 1.5e-15 57.0 1.8 2.4e-15 56.4 0.1 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG74131.1 - 9.9e-12 45.1 0.0 2.8e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74131.1 - 8.3e-06 25.9 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1180 PF06679.12 GBG74132.1 - 5.6 7.3 9.4 0.15 12.5 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1180) MAP65_ASE1 PF03999.12 GBG74132.1 - 5.9 5.5 19.2 9 4.9 19.2 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pkinase PF00069.25 GBG74133.1 - 2.9e-12 46.5 0.0 3.1e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Integrase_H2C2 PF17921.1 GBG74134.1 - 5.6e-17 61.6 0.3 2.1e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG74134.1 - 2.6e-12 46.5 0.0 6e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG74134.1 - 1.3e-09 38.3 0.0 3.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74134.1 - 0.00025 21.2 0.0 0.00053 20.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF3439 PF11921.8 GBG74134.1 - 0.037 14.0 4.8 0.078 12.9 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RFC1 PF08519.12 GBG74134.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain BSP_II PF05432.11 GBG74134.1 - 0.39 10.4 22.7 0.58 9.8 22.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2457 PF10446.9 GBG74134.1 - 1 8.4 14.5 1.9 7.6 14.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF659 PF04937.15 GBG74136.1 - 3.6e-08 33.4 0.0 5.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) YjeF_N PF03853.15 GBG74136.1 - 0.099 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus WD40 PF00400.32 GBG74137.1 - 2.1e-07 31.5 11.0 0.00023 21.9 0.6 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG74137.1 - 2.7e-05 24.4 2.4 0.89 9.9 0.0 5.2 6 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain RT_RNaseH_2 PF17919.1 GBG74139.1 - 3.3e-23 81.6 0.0 8.6e-23 80.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74139.1 - 1.5e-19 70.2 0.0 4.5e-19 68.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74139.1 - 2.6e-19 69.6 0.0 1.2e-18 67.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG74139.1 - 0.00023 21.4 0.0 0.0016 18.6 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein SNAPc19 PF15497.6 GBG74139.1 - 0.15 12.6 0.1 0.47 11.0 0.0 1.8 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 F-box-like PF12937.7 GBG74140.1 - 6e-09 35.7 1.1 4.2e-08 32.9 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GBG74140.1 - 1.3e-08 34.5 0.5 1.3e-07 31.3 0.4 2.5 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 GBG74140.1 - 0.0007 19.9 0.0 0.011 16.1 0.0 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) FAD_binding_7 PF03441.14 GBG74140.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase Histone PF00125.24 GBG74141.1 - 2.4e-07 31.2 0.1 2.4e-07 31.2 0.1 2.5 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 RT_RNaseH_2 PF17919.1 GBG74142.1 - 1.8e-31 108.1 0.0 4.1e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74142.1 - 1.2e-30 105.9 0.0 4.2e-24 84.8 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74142.1 - 6.7e-18 65.0 0.0 2.2e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG74142.1 - 1.9e-12 47.1 0.0 6.1e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG74143.1 - 1.8e-34 119.2 0.0 2.8e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74143.1 - 4.8e-21 74.7 0.0 9.8e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74143.1 - 4.1e-08 33.5 0.0 9.2e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Ferritin PF00210.24 GBG74144.1 - 0.023 14.6 1.3 0.87 9.5 0.0 2.2 1 1 1 2 2 2 0 Ferritin-like domain YabA PF06156.13 GBG74144.1 - 0.071 13.7 0.4 0.14 12.8 0.0 1.6 2 0 0 2 2 2 0 Initiation control protein YabA FSA_C PF10479.9 GBG74144.1 - 0.073 11.2 0.8 0.087 10.9 0.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus GCN5L1 PF06320.13 GBG74144.1 - 0.1 12.7 4.4 0.098 12.8 3.0 1.6 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) PP2C PF00481.21 GBG74145.1 - 1.5e-35 123.0 0.1 3.2e-34 118.7 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Aminopep PF10023.9 GBG74145.1 - 0.076 12.4 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative aminopeptidase EGF_CA PF07645.15 GBG74147.1 - 4.7e-14 52.3 38.6 5e-07 29.8 5.1 4.5 3 1 1 4 4 4 4 Calcium-binding EGF domain cEGF PF12662.7 GBG74147.1 - 1.2e-07 31.5 31.0 0.00011 22.0 2.9 4.8 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.27 GBG74147.1 - 2.8e-07 30.7 55.7 0.00029 21.1 9.3 5.6 5 1 0 5 5 5 4 EGF-like domain hEGF PF12661.7 GBG74147.1 - 9.8e-05 22.8 21.2 0.00082 19.9 7.7 7.4 9 0 0 9 9 9 3 Human growth factor-like EGF EGF_3 PF12947.7 GBG74147.1 - 0.0024 18.0 40.7 0.29 11.3 4.1 5.4 5 0 0 5 5 5 4 EGF domain Plasmod_Pvs28 PF06247.11 GBG74147.1 - 0.0028 17.9 28.0 0.0031 17.8 0.8 4.7 5 1 0 5 5 5 3 Pvs28 EGF domain FXa_inhibition PF14670.6 GBG74147.1 - 0.0056 16.9 45.3 0.0074 16.5 6.1 4.8 2 2 1 4 4 4 2 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 GBG74147.1 - 0.32 11.4 55.2 0.28 11.6 6.9 5.5 4 1 0 4 4 4 0 EGF-like domain EGF_MSP1_1 PF12946.7 GBG74147.1 - 0.58 10.2 31.3 0.15 12.1 3.0 4.0 4 0 0 4 4 4 0 MSP1 EGF domain 1 TTSSLRR PF12468.8 GBG74148.1 - 0.0073 16.5 0.1 0.019 15.2 0.1 1.7 1 0 0 1 1 1 1 Type III secretion system leucine rich repeat protein Myb_DNA-bind_4 PF13837.6 GBG74149.1 - 9.6e-05 22.7 1.5 0.0002 21.7 1.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain GluR_Homer-bdg PF10606.9 GBG74149.1 - 0.25 11.5 5.8 2.6 8.3 2.0 3.2 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor DDE_Tnp_4 PF13359.6 GBG74150.1 - 2.2e-25 89.2 0.0 3e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74150.1 - 6e-17 61.9 0.0 9.6e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG74150.1 - 0.012 15.3 0.1 3.1 7.4 0.0 2.7 2 1 0 2 2 2 0 Transposase DDE domain DUF1206 PF06724.11 GBG74150.1 - 0.1 12.7 0.9 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) RVT_1 PF00078.27 GBG74151.1 - 3.1e-26 92.3 0.8 6e-26 91.3 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG74152.1 - 1.7e-05 25.0 8.1 0.0096 16.2 0.3 4.5 4 0 0 4 4 4 2 Retrotransposon gag protein SlyX PF04102.12 GBG74152.1 - 0.014 16.0 0.1 0.014 16.0 0.1 4.8 4 0 0 4 4 4 0 SlyX DUF572 PF04502.13 GBG74152.1 - 9.2 5.8 15.2 5.1 6.6 5.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) RT_RNaseH PF17917.1 GBG74153.1 - 1.3e-29 102.6 0.0 2.6e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74153.1 - 2.3e-29 101.4 0.0 1.2e-13 51.0 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74153.1 - 4.1e-28 98.4 0.1 6.8e-28 97.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74153.1 - 8.4e-13 48.2 0.1 1.7e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74153.1 - 4.2e-05 23.7 0.0 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74153.1 - 0.00094 19.4 0.0 0.0024 18.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Conotoxin PF02950.17 GBG74153.1 - 0.52 11.4 1.3 2.1 9.4 0.9 2.1 2 0 0 2 2 2 0 Conotoxin RNA_pol_Rpc4 PF05132.14 GBG74153.1 - 0.56 10.6 1.9 1.3 9.5 1.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 XAP5 PF04921.14 GBG74153.1 - 2.2 8.1 5.5 3.9 7.2 5.5 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.14 GBG74153.1 - 4 5.6 9.5 6.4 4.9 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG74153.1 - 5.6 6.3 15.2 8.1 5.8 15.2 1.1 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 GBG74153.1 - 9.3 5.1 15.5 15 4.4 15.5 1.2 1 0 0 1 1 1 0 Paf1 Cupin_2 PF07883.11 GBG74154.1 - 0.048 13.4 0.3 0.42 10.4 0.3 2.2 1 1 0 1 1 1 0 Cupin domain DUF4834 PF16118.5 GBG74154.1 - 0.29 12.1 1.6 0.86 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Myb_DNA-bind_4 PF13837.6 GBG74155.1 - 2.4e-05 24.6 3.9 4.4e-05 23.8 3.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG74155.1 - 0.35 11.1 5.8 1.6 9.0 5.8 2.4 1 1 0 1 1 1 0 Myb-like DNA-binding domain ubiquitin PF00240.23 GBG74156.1 - 7.5e-194 627.9 31.2 6.6e-33 112.3 0.6 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.8 GBG74156.1 - 3.3e-91 299.2 33.7 2e-15 56.4 0.8 6.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GBG74156.1 - 9.3e-32 109.3 17.4 0.0011 19.3 0.1 8.1 6 6 0 6 6 6 6 Ubiquitin-like domain TBK1_ULD PF18396.1 GBG74156.1 - 5e-22 77.6 10.4 0.055 13.4 0.0 6.2 6 0 0 6 6 6 6 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GBG74156.1 - 2.9e-19 69.2 6.4 0.26 11.4 0.1 7.0 5 4 1 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GBG74156.1 - 3.6e-19 69.2 4.3 0.17 12.5 0.0 6.2 1 1 2 6 6 6 6 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 GBG74156.1 - 4.1e-19 68.7 14.7 0.11 12.8 0.1 6.1 6 0 0 6 6 6 6 Ubiquitin-like domain Methyltrans_RNA PF04452.14 GBG74156.1 - 6.4e-08 32.2 3.5 2.4 7.4 0.0 4.6 5 0 0 5 5 5 4 RNA methyltransferase DUF2870 PF11069.8 GBG74156.1 - 1.4e-07 31.8 0.0 79 3.7 0.0 6.6 6 0 0 6 6 6 0 Protein of unknown function (DUF2870) Big_7 PF17957.1 GBG74156.1 - 6.5e-07 30.0 0.5 58 4.6 0.0 5.3 5 0 0 5 5 5 0 Bacterial Ig domain DUF969 PF06149.12 GBG74156.1 - 9.7e-07 28.4 0.4 32 3.9 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF969) Ubiquitin_4 PF18036.1 GBG74156.1 - 1.4e-06 28.2 35.5 28 4.8 0.2 10.9 11 0 0 11 11 11 0 Ubiquitin-like domain DUF3861 PF12977.7 GBG74156.1 - 2.9e-06 27.4 8.2 19 5.5 0.0 5.7 6 0 0 6 6 6 0 Domain of Unknown Function with PDB structure (DUF3861) UDP-g_GGTase PF06427.11 GBG74156.1 - 1.6e-05 24.9 5.8 15 5.8 0.0 5.0 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_3_3 PF13750.6 GBG74156.1 - 2e-05 24.3 0.4 54 3.4 0.0 5.3 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) NEAT PF05031.12 GBG74156.1 - 3.5e-05 24.4 5.7 0.81 10.3 0.3 3.7 1 1 4 5 5 5 4 Iron Transport-associated domain ACT_5 PF13710.6 GBG74156.1 - 0.00013 21.7 8.2 31 4.5 0.0 5.3 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 GBG74156.1 - 0.00052 20.5 0.2 2e+02 2.6 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 GBG74156.1 - 0.0007 19.7 0.0 2.4e+02 1.9 0.0 6.1 6 0 0 6 6 6 0 ORF11CD3 domain ACT_4 PF13291.6 GBG74156.1 - 0.0016 19.0 2.6 1.9e+02 2.7 0.0 5.3 5 0 0 5 5 5 0 ACT domain YcgR_2 PF12945.7 GBG74156.1 - 0.01 15.9 10.0 74 3.6 0.1 5.3 5 0 0 5 5 5 0 Flagellar protein YcgR Phage-tail_1 PF09097.10 GBG74156.1 - 0.27 11.0 4.1 2.2e+02 1.5 0.0 4.8 6 0 0 6 6 5 0 Baseplate structural protein, domain 1 ProRS-C_2 PF09181.10 GBG74156.1 - 0.35 11.0 11.2 1.8e+02 2.4 0.1 5.8 6 0 0 6 6 6 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 GBG74156.1 - 0.45 10.7 36.0 9.5 6.5 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 GBG74156.1 - 1.2 9.6 14.4 1.8e+02 2.6 0.1 5.0 1 1 1 2 2 1 0 Phage tail sheath protein beta-sandwich domain RT_RNaseH PF17917.1 GBG74158.1 - 1.3e-21 76.9 0.0 2.5e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74158.1 - 2.1e-20 72.6 0.0 4.5e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74158.1 - 7.4e-11 42.0 0.4 2e-10 40.6 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG74158.1 - 1.9e-08 34.7 0.2 1.4e-07 32.0 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG74158.1 - 2.1e-06 27.4 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG74158.1 - 8.5e-05 23.1 0.0 0.0003 21.4 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG74158.1 - 0.033 14.0 0.2 0.074 12.8 0.2 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG74158.1 - 0.18 12.2 0.0 0.46 10.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease ubiquitin PF00240.23 GBG74159.1 - 5.4e-168 545.1 26.9 5.2e-33 112.6 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 GBG74159.1 - 4.1e-80 263.6 29.8 1.6e-15 56.7 0.8 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GBG74159.1 - 3.6e-27 94.6 14.1 0.0009 19.7 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 GBG74159.1 - 3.8e-19 68.4 7.2 0.044 13.7 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GBG74159.1 - 1.4e-16 60.5 5.2 0.24 11.5 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GBG74159.1 - 1.5e-16 60.8 3.2 0.31 11.6 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 GBG74159.1 - 1.8e-16 60.3 12.2 0.09 13.1 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Methyltrans_RNA PF04452.14 GBG74159.1 - 1.6e-08 34.2 2.0 1.9 7.7 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase DUF3861 PF12977.7 GBG74159.1 - 3.2e-07 30.4 5.6 16 5.8 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 GBG74159.1 - 5.6e-07 30.2 1.3 48 4.8 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain Ubiquitin_4 PF18036.1 GBG74159.1 - 1.4e-06 28.2 32.6 23 5.1 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF2870 PF11069.8 GBG74159.1 - 2.6e-06 27.7 0.0 66 4.0 0.0 5.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Big_3_3 PF13750.6 GBG74159.1 - 1.1e-05 25.2 0.4 44 3.7 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) DUF969 PF06149.12 GBG74159.1 - 1.1e-05 25.0 0.3 25 4.2 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF969) NEAT PF05031.12 GBG74159.1 - 1.3e-05 25.7 5.0 0.58 10.8 0.2 3.5 1 1 3 4 4 4 4 Iron Transport-associated domain UDP-g_GGTase PF06427.11 GBG74159.1 - 2e-05 24.6 7.0 11 6.1 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 GBG74159.1 - 5.9e-05 22.8 8.2 26 4.8 0.0 5.3 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 GBG74159.1 - 0.00024 21.6 0.2 1.7e+02 2.9 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ACT_4 PF13291.6 GBG74159.1 - 0.00082 19.9 2.6 1.6e+02 3.0 0.0 5.1 5 0 0 5 5 5 0 ACT domain ORF11CD3 PF10549.9 GBG74159.1 - 0.0038 17.3 0.0 2e+02 2.2 0.0 5.3 5 0 0 5 5 5 0 ORF11CD3 domain YcgR_2 PF12945.7 GBG74159.1 - 0.0051 16.9 10.0 61 3.9 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR Phage-tail_1 PF09097.10 GBG74159.1 - 0.04 13.7 2.1 1.8e+02 1.8 0.0 4.6 5 0 0 5 5 5 0 Baseplate structural protein, domain 1 Phage_sheath_1N PF17481.2 GBG74159.1 - 0.18 12.3 12.7 83 3.7 0.2 4.9 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain ProRS-C_2 PF09181.10 GBG74159.1 - 0.2 11.8 9.2 1.5e+02 2.6 0.1 5.0 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 GBG74159.1 - 0.21 11.8 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Myosin_N PF02736.19 GBG74159.1 - 0.29 11.0 9.4 1.4e+02 2.4 0.0 6.1 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain FlgD_ig PF13860.6 GBG74159.1 - 2.6 8.0 13.8 1.2e+02 2.6 0.1 5.2 5 0 0 5 5 5 0 FlgD Ig-like domain RT_RNaseH PF17917.1 GBG74160.1 - 2e-22 79.4 0.0 5e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74160.1 - 1.5e-13 50.6 0.0 7e-11 42.1 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74160.1 - 1.7e-13 50.4 1.2 5.4e-13 48.8 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG74160.1 - 1.7e-11 43.8 0.0 3.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG74160.1 - 3.5e-07 30.0 2.1 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG74160.1 - 0.019 15.2 0.0 0.055 13.7 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Nop14 PF04147.12 GBG74161.1 - 0.093 10.9 22.1 0.1 10.8 22.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 GBG74161.1 - 0.11 11.6 21.3 0.13 11.4 21.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 GBG74161.1 - 0.21 11.0 22.4 0.25 10.8 22.4 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG74161.1 - 0.59 8.7 29.9 0.78 8.3 29.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TbpB_B_D PF01298.18 GBG74161.1 - 0.72 10.3 7.8 2.2 8.7 7.8 1.9 1 1 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B CDC45 PF02724.14 GBG74161.1 - 0.72 8.1 18.7 0.95 7.7 18.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG74161.1 - 0.75 7.8 29.5 0.92 7.5 29.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 GBG74161.1 - 0.84 8.6 18.7 1 8.4 18.7 1.2 1 0 0 1 1 1 0 Pes-10 TRAP_alpha PF03896.16 GBG74161.1 - 1.2 8.3 10.3 1.4 8.0 10.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2201_N PF13203.6 GBG74161.1 - 1.2 8.7 5.5 2.1 7.9 5.5 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain PIG-S PF10510.9 GBG74161.1 - 1.9 7.2 4.6 2.3 6.9 4.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein NPR3 PF03666.13 GBG74161.1 - 2.3 6.9 7.8 2.8 6.6 7.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GBG74161.1 - 3.7 6.2 5.9 4.1 6.1 5.9 1.2 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GBG74161.1 - 4.3 6.6 21.3 5.5 6.2 21.3 1.2 1 0 0 1 1 1 0 BUD22 Utp14 PF04615.13 GBG74161.1 - 5.2 5.5 20.0 6.3 5.2 20.0 1.0 1 0 0 1 1 1 0 Utp14 protein Pox_Ag35 PF03286.14 GBG74161.1 - 6 6.6 18.4 12 5.7 18.4 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_Rpc4 PF05132.14 GBG74161.1 - 6.1 7.3 8.2 12 6.4 8.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 PI3K_1B_p101 PF10486.9 GBG74161.1 - 6.2 4.5 9.9 7.6 4.2 9.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF913 PF06025.12 GBG74161.1 - 6.7 5.6 7.0 7.8 5.4 7.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RVT_1 PF00078.27 GBG74162.1 - 1.5e-12 47.5 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG74163.1 - 0.076 11.2 21.3 0.096 10.9 21.3 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG74163.1 - 0.15 11.4 20.5 0.19 11.1 20.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG74163.1 - 0.92 7.7 17.6 1.3 7.3 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TbpB_B_D PF01298.18 GBG74163.1 - 0.95 9.9 5.6 1.6 9.1 5.1 1.6 1 1 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B SH3_12 PF18129.1 GBG74163.1 - 2 8.6 16.7 1.4 9.1 3.3 3.9 4 0 0 4 4 4 0 Xrn1 SH3-like domain DUF2457 PF10446.9 GBG74163.1 - 2.3 7.3 25.8 3.1 6.9 25.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GBG74163.1 - 4.2 5.4 29.5 5.4 5.0 29.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 GBG74163.1 - 5.4 6.2 20.8 7 5.9 20.8 1.1 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 GBG74163.1 - 6.8 5.4 8.8 8.6 5.0 8.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SH3_18 PF18354.1 GBG74163.1 - 7 6.8 11.0 1.7 8.7 0.2 3.3 3 0 0 3 3 3 0 CarS bacterial SH3 domain RNA_pol_Rpc4 PF05132.14 GBG74163.1 - 8.4 6.8 8.5 16 5.9 8.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Myb_DNA-bind_4 PF13837.6 GBG74164.1 - 2e-08 34.5 0.7 2e-08 34.5 0.7 2.0 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain DUF3253 PF11625.8 GBG74164.1 - 0.0082 16.4 0.4 0.84 9.9 0.2 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3253) MADF_DNA_bdg PF10545.9 GBG74164.1 - 0.21 11.9 1.9 0.3 11.4 0.1 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like UPF0231 PF06062.11 GBG74166.1 - 0.014 15.7 2.2 0.76 10.1 0.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) CBM65_1 PF18259.1 GBG74166.1 - 0.11 12.6 0.4 2.5 8.3 0.1 2.0 1 1 1 2 2 2 0 Carbohydrate binding module 65 domain 1 RVT_1 PF00078.27 GBG74167.1 - 1.3e-09 37.9 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAPS PF04499.15 GBG74167.1 - 0.47 9.2 2.7 0.47 9.2 0.4 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Synaphin PF05835.12 GBG74169.1 - 0.041 14.2 23.6 0.051 13.9 23.6 1.2 1 0 0 1 1 1 0 Synaphin protein Cas_CT1975 PF09344.10 GBG74169.1 - 1.7 8.0 9.9 1.9 7.8 9.9 1.0 1 0 0 1 1 1 0 CT1975-like protein DUF4746 PF15928.5 GBG74169.1 - 4.2 6.7 10.2 4.9 6.5 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Aminotran_1_2 PF00155.21 GBG74171.1 - 2.8e-62 211.0 0.0 3.8e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SelP_N PF04592.14 GBG74172.1 - 0.033 13.6 1.9 0.039 13.4 1.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CEL_III_C PF18054.1 GBG74172.1 - 1 9.4 10.8 1.4 9.0 10.8 1.2 1 0 0 1 1 1 0 CEL-III C-terminal AF-4 PF05110.13 GBG74172.1 - 1.1 7.3 3.5 1.2 7.1 3.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pkinase PF00069.25 GBG74173.1 - 1.7e-58 198.1 0.0 2e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG74173.1 - 8.9e-31 107.1 0.0 1.1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG74173.1 - 0.00062 19.2 0.0 0.00086 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF2647 PF10839.8 GBG74173.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) RT_RNaseH PF17917.1 GBG74174.1 - 3.8e-21 75.3 0.0 2.9e-20 72.5 0.0 2.4 1 1 2 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74174.1 - 1.9e-12 47.1 0.0 6.8e-12 45.3 0.0 1.9 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG74174.1 - 0.029 12.6 5.2 0.047 11.9 5.2 1.3 1 0 0 1 1 1 0 Nop14-like family gag-asp_proteas PF13975.6 GBG74174.1 - 0.031 14.8 0.0 0.055 14.0 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HTH_32 PF13565.6 GBG74174.1 - 0.055 14.1 0.1 1.1 10.0 0.1 2.7 2 0 0 2 2 2 0 Homeodomain-like domain Asp_protease_2 PF13650.6 GBG74174.1 - 0.15 12.7 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease CDC45 PF02724.14 GBG74174.1 - 0.91 7.7 7.8 1.4 7.2 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG74174.1 - 6 6.1 14.7 14 4.9 0.3 2.1 2 0 0 2 2 2 0 BUD22 U-box PF04564.15 GBG74175.1 - 3.1e-21 75.3 0.0 1.1e-20 73.5 0.0 2.0 2 0 0 2 2 2 1 U-box domain Arm PF00514.23 GBG74175.1 - 2.6e-06 27.3 0.0 0.96 9.6 0.0 4.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat BAF250_C PF12031.8 GBG74175.1 - 0.034 13.4 0.1 5 6.3 0.0 2.4 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa zf-Nse PF11789.8 GBG74175.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 GBG74176.1 - 1.5e-14 53.9 0.0 7.8e-14 51.6 0.0 2.4 2 0 0 2 2 2 1 U-box domain Arm PF00514.23 GBG74176.1 - 5e-05 23.2 0.3 7.9 6.7 0.0 5.3 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat zf-Nse PF11789.8 GBG74176.1 - 0.0016 18.2 0.3 0.0051 16.6 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DUF659 PF04937.15 GBG74177.1 - 1.1e-17 64.3 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PA26 PF04636.13 GBG74180.1 - 3.3 6.5 9.0 4.8 6.0 9.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) M16C_assoc PF08367.11 GBG74181.1 - 6.7e-77 258.0 0.0 9.2e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 GBG74181.1 - 1.2e-27 97.1 0.0 2.3e-23 83.2 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GBG74181.1 - 0.00019 21.4 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF287 PF03384.14 GBG74182.1 - 0.47 10.9 4.0 0.36 11.3 0.6 2.5 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 CYYR1 PF10873.8 GBG74183.1 - 0.042 14.3 0.1 0.052 14.0 0.1 1.2 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 gag-asp_proteas PF13975.6 GBG74184.1 - 7.5e-06 26.4 0.1 2e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74184.1 - 0.00012 22.6 0.1 0.00035 21.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG74184.1 - 0.0011 18.7 0.6 0.0027 17.5 0.1 1.9 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 GBG74184.1 - 0.11 12.6 1.9 0.22 11.6 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle DAGK_acc PF00609.19 GBG74185.1 - 2.4e-23 83.3 0.0 1e-22 81.2 0.0 2.0 2 1 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 GBG74185.1 - 5.3e-20 71.3 0.0 9.6e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 GBG74186.1 - 4.9e-23 82.2 0.0 2.3e-22 80.0 0.0 2.0 2 1 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 GBG74186.1 - 5.4e-20 71.3 0.0 9.6e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain APOBEC_C PF05240.14 GBG74187.1 - 0.13 12.3 0.2 0.32 11.0 0.2 1.7 1 0 0 1 1 1 0 APOBEC-like C-terminal domain VEFS-Box PF09733.9 GBG74187.1 - 0.22 11.3 0.9 12 5.7 0.3 2.2 2 0 0 2 2 2 0 VEFS-Box of polycomb protein PPP4R2 PF09184.11 GBG74188.1 - 4e-16 59.5 0.2 1.6e-15 57.5 0.2 2.2 1 1 0 1 1 1 1 PPP4R2 FA_FANCE PF11510.8 GBG74189.1 - 3.5e-06 26.6 3.1 0.0052 16.2 0.2 2.5 3 0 0 3 3 3 2 Fanconi Anaemia group E protein FANCE OB_NTP_bind PF07717.16 GBG74190.1 - 2.1e-15 56.8 0.0 4.5e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GBG74190.1 - 8.7e-15 54.9 0.0 3.6e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GBG74190.1 - 3.2e-11 43.6 0.0 6.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GBG74190.1 - 2.9e-06 27.6 0.0 7.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 GBG74190.1 - 5.9e-06 26.2 0.0 1.5e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GBG74190.1 - 1.9e-05 24.5 0.0 6.2e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 GBG74190.1 - 0.00036 20.4 0.0 0.00073 19.4 0.0 1.5 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.6 GBG74190.1 - 0.003 17.9 0.1 0.006 16.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GBG74190.1 - 0.019 15.4 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.14 GBG74190.1 - 0.023 14.7 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_29 PF13555.6 GBG74190.1 - 0.026 14.3 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GBG74190.1 - 0.081 13.4 0.9 0.2 12.1 0.9 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 GBG74190.1 - 0.093 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 GBG74190.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 GBG74190.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 GBG74190.1 - 0.13 12.0 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PAPA-1 PF04795.12 GBG74191.1 - 4.9e-15 56.1 10.3 4.9e-15 56.1 10.3 3.9 4 0 0 4 4 4 1 PAPA-1-like conserved region zf-HIT PF04438.16 GBG74191.1 - 1.4e-07 31.3 9.4 2e-07 30.8 9.4 1.3 1 0 0 1 1 1 1 HIT zinc finger eIF-3c_N PF05470.12 GBG74191.1 - 3.5 5.8 5.9 7 4.8 5.9 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus EF-hand_1 PF00036.32 GBG74192.1 - 2.2e-32 108.2 12.3 3.5e-08 32.4 1.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GBG74192.1 - 1.1e-29 102.6 8.7 4.1e-16 59.2 1.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG74192.1 - 5.9e-26 88.1 8.9 1.5e-08 33.9 0.1 4.8 3 1 2 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 GBG74192.1 - 1.2e-25 87.8 10.0 2.6e-06 26.7 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GBG74192.1 - 3.2e-21 74.9 12.8 1e-10 41.3 1.0 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 GBG74192.1 - 3.8e-09 36.7 0.9 3.5e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GBG74192.1 - 1.5e-06 28.5 0.5 0.041 14.2 0.1 2.8 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 GBG74192.1 - 0.00012 22.0 1.7 0.33 10.9 0.0 3.0 2 2 2 4 4 4 2 Caleosin related protein EF-hand_4 PF12763.7 GBG74192.1 - 0.039 13.9 2.0 0.42 10.6 0.1 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EAP30 PF04157.16 GBG74192.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family Glyco_hydro_56 PF01630.18 GBG74192.1 - 0.17 10.9 0.0 9.9 5.0 0.0 2.1 2 0 0 2 2 2 0 Hyaluronidase Menin PF05053.13 GBG74193.1 - 3.8 5.8 19.9 5.3 5.3 19.9 1.1 1 0 0 1 1 1 0 Menin RVT_1 PF00078.27 GBG74194.1 - 3.5e-31 108.4 0.1 4.8e-31 108.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74194.1 - 1e-14 54.4 0.0 1.9e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74194.1 - 0.0031 17.8 0.0 0.0065 16.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5095 PF17016.5 GBG74194.1 - 0.09 12.5 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) RT_RNaseH_2 PF17919.1 GBG74195.1 - 9.9e-53 176.3 0.0 4.3e-31 106.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74195.1 - 2.2e-43 146.8 0.1 1.8e-22 79.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74195.1 - 1e-30 106.9 1.3 1.6e-17 63.8 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG74195.1 - 1.9e-15 57.1 0.0 5.8e-15 55.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG74195.1 - 1.8e-05 24.9 6.8 0.028 14.7 0.0 3.5 3 0 0 3 3 3 2 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG74195.1 - 0.0088 16.1 0.2 0.024 14.7 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG74195.1 - 0.028 15.0 0.0 0.11 13.0 0.0 2.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease GCS2 PF04107.13 GBG74196.1 - 8.1e-87 291.2 0.0 1.2e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) RT_RNaseH PF17917.1 GBG74197.1 - 5.2e-58 193.8 0.8 1.8e-28 98.9 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74197.1 - 1e-55 185.9 0.0 6.8e-32 109.5 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74197.1 - 6.9e-38 128.6 5.1 7e-19 67.7 0.2 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG74197.1 - 4.3e-33 114.7 0.2 1.2e-29 103.5 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG74197.1 - 8.7e-15 55.0 0.0 2.9e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74197.1 - 1.1e-08 35.2 0.3 0.0021 18.2 0.0 2.6 2 0 0 2 2 2 2 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG74197.1 - 3.5e-05 24.3 0.0 0.00011 22.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1564 PF07600.11 GBG74197.1 - 0.0076 15.9 0.0 0.039 13.7 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) PapD-like PF14874.6 GBG74197.1 - 0.018 15.2 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Flagellar-associated PapD-like Asp_protease_2 PF13650.6 GBG74197.1 - 0.018 15.7 0.0 0.045 14.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG74199.1 - 5.1e-20 71.9 0.0 8e-10 38.6 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG74199.1 - 2.3e-10 40.4 0.1 8.7e-10 38.5 0.1 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 GBG74199.1 - 4e-08 33.9 0.1 1.7e-07 31.8 0.1 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 GBG74199.1 - 1.2e-06 28.3 0.0 5.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Chromo PF00385.24 GBG74200.1 - 0.0063 16.4 0.2 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG74200.1 - 0.073 13.3 1.9 0.21 11.9 0.0 2.7 3 1 0 3 3 3 0 Retrotransposon gag protein Red1 PF07964.11 GBG74201.1 - 3.4 5.8 12.0 4.2 5.5 12.0 1.0 1 0 0 1 1 1 0 Rec10 / Red1 rve PF00665.26 GBG74202.1 - 0.0025 18.0 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF4219 PF13961.6 GBG74202.1 - 0.044 13.5 0.1 2.8 7.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) rve_3 PF13683.6 GBG74202.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain 6PGD PF00393.19 GBG74204.1 - 1.3e-127 425.2 0.0 1.7e-127 424.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GBG74204.1 - 1.7e-49 168.1 0.1 3.2e-49 167.1 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 GBG74204.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GBG74204.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 GBG74204.1 - 0.028 15.0 0.0 0.062 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GBG74204.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF732 PF05305.14 GBG74204.1 - 0.19 12.2 0.4 0.59 10.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF732) RT_RNaseH PF17917.1 GBG74205.1 - 4.4e-48 161.9 0.0 5.2e-27 94.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74205.1 - 1.7e-44 149.9 0.0 2.2e-32 111.1 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG74205.1 - 1.9e-05 24.5 3.2 3.5e-05 23.7 3.2 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG74205.1 - 0.04 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GBG74205.1 - 0.041 13.7 4.1 0.068 13.0 4.1 1.3 1 0 0 1 1 1 0 Zinc knuckle WRW PF10206.9 GBG74206.1 - 0.1 13.0 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Retrotrans_gag PF03732.17 GBG74208.1 - 0.012 15.9 0.7 0.036 14.3 0.0 2.3 3 0 0 3 3 3 0 Retrotransposon gag protein RAP1 PF07218.11 GBG74208.1 - 0.03 12.6 2.1 0.046 12.0 2.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Noelin-1 PF12308.8 GBG74208.1 - 0.19 11.7 2.0 0.52 10.3 0.4 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein PC-Esterase PF13839.6 GBG74209.1 - 1.7e-64 218.3 0.2 2.6e-64 217.7 0.2 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 GBG74209.1 - 3.3e-15 56.1 2.6 6.5e-15 55.2 2.6 1.5 1 0 0 1 1 1 1 PMR5 N terminal Domain PIG-U PF06728.13 GBG74210.1 - 2e-93 313.5 17.5 2.3e-52 178.3 17.3 2.2 2 0 0 2 2 2 2 GPI transamidase subunit PIG-U Y_phosphatase PF00102.27 GBG74211.1 - 3.5e-58 197.0 0.0 4.1e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GBG74211.1 - 0.00015 21.8 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GBG74211.1 - 0.0015 18.3 0.6 0.0046 16.8 0.2 2.0 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DDE_Tnp_4 PF13359.6 GBG74212.1 - 1.9e-06 27.6 0.0 4e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74212.1 - 0.028 14.0 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein Calcipressin PF04847.12 GBG74213.1 - 0.016 15.0 1.7 0.076 12.7 0.1 2.3 2 1 0 2 2 2 0 Calcipressin SDA1 PF05285.12 GBG74213.1 - 0.75 9.2 5.7 1 8.7 5.7 1.2 1 0 0 1 1 1 0 SDA1 Inhibitor_I66 PF16850.5 GBG74214.1 - 0.077 12.9 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I66 DUF1658 PF07871.11 GBG74214.1 - 0.68 10.0 7.5 12 6.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Pkinase PF00069.25 GBG74215.1 - 1.9e-76 256.9 0.0 2.4e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG74215.1 - 3.5e-35 121.5 0.0 4.8e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG74215.1 - 5.2e-06 26.0 0.1 0.001 18.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 GBG74215.1 - 0.0078 15.2 0.1 0.022 13.7 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 GBG74215.1 - 0.098 11.7 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 GBG74215.1 - 0.16 11.9 0.1 2.2 8.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_C2 PF00648.21 GBG74216.1 - 0.02 14.0 0.9 0.028 13.5 0.9 1.1 1 0 0 1 1 1 0 Calpain family cysteine protease FOXP-CC PF16159.5 GBG74216.1 - 0.094 13.4 1.1 0.25 12.0 0.4 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain LMBR1 PF04791.16 GBG74216.1 - 1.3 7.8 5.1 1.8 7.4 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LPP PF04728.13 GBG74216.1 - 4.1 7.9 7.1 1.6 9.2 0.3 3.0 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF2514 PF10721.9 GBG74216.1 - 4.3 7.4 12.7 6.7 6.7 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Casc1_N PF15927.5 GBG74216.1 - 7.8 6.1 19.8 1.3 8.7 9.2 2.2 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus HCMV_UL139 PF12507.8 GBG74216.1 - 9.5 6.6 9.6 73 3.8 0.1 3.2 1 1 2 3 3 3 0 Human Cytomegalovirus UL139 protein AAA PF00004.29 GBG74217.1 - 5.6e-15 55.9 0.0 1.6e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 GBG74217.1 - 0.0026 17.6 0.1 0.0066 16.3 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M41 MscS_porin PF12795.7 GBG74217.1 - 0.059 12.9 4.2 0.12 11.9 4.2 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain CENP-K PF11802.8 GBG74217.1 - 2.5 7.6 6.2 0.32 10.5 1.6 1.8 2 0 0 2 2 2 0 Centromere-associated protein K PALP PF00291.25 GBG74218.1 - 2.8e-62 210.8 3.0 4.3e-30 105.1 0.1 3.0 3 0 0 3 3 3 2 Pyridoxal-phosphate dependent enzyme Draxin PF15550.6 GBG74218.1 - 0.71 9.7 6.0 1.2 8.9 6.0 1.3 1 0 0 1 1 1 0 Draxin UCH PF00443.29 GBG74219.1 - 1.8e-26 93.2 0.0 2.7e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_photolyase PF00875.18 GBG74221.1 - 1.1e-28 100.3 0.0 1.9e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DNA_photolyase PF00875.18 GBG74222.1 - 1.1e-28 100.3 0.0 1.9e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase RNA_pol_Rpb4 PF03874.16 GBG74223.1 - 9.1e-21 74.5 0.1 1.2e-20 74.1 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 TRAF_BIRC3_bd PF16673.5 GBG74223.1 - 0.0053 16.5 0.3 0.17 11.7 0.1 2.3 2 0 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain WSD PF15613.6 GBG74223.1 - 0.13 12.8 0.1 0.18 12.3 0.1 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF5091 PF17012.5 GBG74223.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5091) zf-CCHC PF00098.23 GBG74224.1 - 3.8e-06 26.7 3.1 6.1e-06 26.1 3.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG74224.1 - 0.028 14.3 3.0 0.054 13.3 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG74224.1 - 0.046 13.4 2.2 0.11 12.2 2.2 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Tubulin PF00091.25 GBG74225.1 - 7.4e-50 169.9 0.0 1.1e-49 169.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain WD40 PF00400.32 GBG74226.1 - 1.6e-14 54.0 0.9 0.018 15.9 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat HTH_31 PF13560.6 GBG74226.1 - 0.095 13.1 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain His_Phos_1 PF00300.22 GBG74227.1 - 8.2e-14 51.7 0.0 2.5e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SMC_N PF02463.19 GBG74228.1 - 3e-59 200.1 38.2 2.2e-34 118.8 10.0 3.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GBG74228.1 - 2.3e-23 82.7 0.0 8.4e-23 80.9 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GBG74228.1 - 8.5e-11 42.2 0.1 4.7e-05 23.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GBG74228.1 - 1e-05 25.4 21.1 1e-05 25.4 21.1 4.1 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 GBG74228.1 - 4.6e-05 23.1 0.0 8.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Exotox-A_target PF09102.10 GBG74228.1 - 0.00094 19.2 1.7 1.4 8.9 0.1 3.0 2 0 0 2 2 2 2 Exotoxin A, targeting Spc7 PF08317.11 GBG74228.1 - 0.033 13.1 122.0 0.07 12.0 14.3 7.4 2 2 6 8 8 8 0 Spc7 kinetochore protein ABC_tran PF00005.27 GBG74228.1 - 0.15 12.5 0.0 0.15 12.5 0.0 5.8 4 2 0 4 4 4 0 ABC transporter NPV_P10 PF05531.12 GBG74228.1 - 3.6 8.1 56.0 1.5 9.4 1.3 10.2 5 2 5 10 10 10 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 GBG74228.1 - 6.1 7.5 71.9 0.9 10.2 4.7 10.8 6 3 4 10 10 10 0 SlyX Arf PF00025.21 GBG74231.1 - 1e-27 96.7 0.0 1.1e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 GBG74231.1 - 0.013 14.5 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Endosulfine PF04667.17 GBG74232.1 - 2.7e-09 37.0 7.1 3.3e-08 33.5 7.1 2.2 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region OSCP PF00213.18 GBG74233.1 - 3.2e-45 154.3 0.0 3.9e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Phage_fiber PF03335.13 GBG74233.1 - 0.16 12.2 3.0 0.44 10.8 3.0 1.6 1 0 0 1 1 1 0 Phage tail fibre repeat DUF604 PF04646.12 GBG74234.1 - 8.4e-87 290.8 0.0 1.2e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 GBG74234.1 - 3.2e-13 49.7 0.0 5.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF3446 PF11928.8 GBG74234.1 - 0.46 10.8 11.0 1.3 9.4 11.0 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain SSP160 PF06933.11 GBG74234.1 - 1.6 6.9 5.9 2.2 6.4 5.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SR-25 PF10500.9 GBG74234.1 - 2.6 7.6 12.2 5.4 6.6 12.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF604 PF04646.12 GBG74235.1 - 7.6e-87 290.9 0.0 1.1e-86 290.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 GBG74235.1 - 3e-13 49.8 0.0 5.1e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF3446 PF11928.8 GBG74235.1 - 0.43 10.9 11.0 1.2 9.5 11.0 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain SSP160 PF06933.11 GBG74235.1 - 1.5 7.0 5.9 2.1 6.4 5.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SR-25 PF10500.9 GBG74235.1 - 2.4 7.7 12.2 5.1 6.6 12.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RT_RNaseH_2 PF17919.1 GBG74236.1 - 2.6e-34 117.3 0.0 5.2e-34 116.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74236.1 - 2.1e-28 98.7 0.3 8.6e-28 96.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74236.1 - 5e-28 98.1 0.0 9e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG74236.1 - 2.7e-07 30.8 0.0 7.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG74236.1 - 8e-06 25.7 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG74236.1 - 0.00099 19.0 0.3 0.0024 17.7 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain UQ_con PF00179.26 GBG74237.1 - 8.9e-43 145.3 0.0 1.5e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PTCB-BRCT PF12738.7 GBG74237.1 - 4.5e-14 52.1 0.8 3.2e-11 43.0 0.1 2.5 2 0 0 2 2 2 2 twin BRCT domain BRCT_2 PF16589.5 GBG74237.1 - 1.2e-11 44.9 0.0 1.2e-05 25.6 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 GBG74237.1 - 9.1e-06 25.9 0.0 0.063 13.6 0.0 2.6 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT PF00533.26 GBG74237.1 - 2.9e-05 24.3 0.0 0.0004 20.7 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RWD PF05773.22 GBG74237.1 - 0.042 14.1 0.1 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 RWD domain UEV PF05743.13 GBG74237.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 UEV domain DUF5344 PF17279.2 GBG74238.1 - 0.16 12.6 3.8 0.33 11.6 0.1 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5344) Peptidase_S55 PF05580.12 GBG74238.1 - 0.2 11.6 4.0 0.065 13.2 0.6 1.8 2 0 0 2 2 2 0 SpoIVB peptidase S55 SHE3 PF17078.5 GBG74238.1 - 0.33 10.6 9.1 2 8.1 3.9 2.8 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF641 PF04859.12 GBG74238.1 - 0.6 10.4 8.3 1.2 9.5 3.4 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.9 GBG74238.1 - 0.62 10.1 16.4 0.24 11.4 1.6 2.7 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 GBG74238.1 - 0.67 9.2 7.0 0.13 11.5 1.7 2.0 2 0 0 2 2 2 0 TMPIT-like protein YabA PF06156.13 GBG74238.1 - 2.2 9.0 7.5 4.6 7.9 0.1 3.3 1 1 2 3 3 3 0 Initiation control protein YabA APG6_N PF17675.1 GBG74238.1 - 5.7 7.5 16.8 2.4 8.7 3.4 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region ACTH_assoc PF16102.5 GBG74239.1 - 0.047 14.5 3.9 10 7.1 0.3 3.2 2 0 0 2 2 2 0 ACTH-associated domain DUF1731 PF08338.11 GBG74240.1 - 0.091 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) gag-asp_proteas PF13975.6 GBG74241.1 - 3.6e-07 30.6 0.6 1e-06 29.2 0.1 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74241.1 - 1.3e-05 25.7 0.9 3.8e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG74241.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74241.1 - 0.0032 17.2 0.1 0.0056 16.5 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG74241.1 - 0.34 11.0 1.9 0.64 10.2 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 GBG74244.1 - 8.4e-50 169.6 0.0 1.1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG74244.1 - 6.9e-45 153.3 0.0 8.8e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG74244.1 - 0.0012 18.8 0.1 0.0028 17.6 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG74244.1 - 0.2 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase IPP-2 PF04979.14 GBG74245.1 - 1.2e-22 81.1 5.2 1.6e-22 80.7 5.2 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) ELH PF02323.15 GBG74245.1 - 0.028 13.8 3.4 0.046 13.1 3.4 1.4 1 0 0 1 1 1 0 Egg-laying hormone precursor YcaO PF02624.16 GBG74245.1 - 0.055 12.7 0.3 0.079 12.2 0.3 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Pes-10 PF07149.11 GBG74245.1 - 5.2 6.0 5.3 7.2 5.6 5.3 1.2 1 0 0 1 1 1 0 Pes-10 HORMA PF02301.18 GBG74246.1 - 4.9e-58 196.2 0.0 4.9e-58 196.2 0.0 2.1 2 0 0 2 2 2 1 HORMA domain Mog1 PF04603.12 GBG74247.1 - 1.2e-36 126.1 0.0 1.4e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Ribosomal_S19 PF00203.21 GBG74248.1 - 2.1e-34 117.3 0.2 2.8e-34 116.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 ALC PF17527.2 GBG74248.1 - 0.21 11.2 0.1 0.36 10.5 0.1 1.3 1 1 0 1 1 1 0 Phage ALC protein zf-CCHC PF00098.23 GBG74249.1 - 0.0039 17.2 4.3 0.0063 16.5 4.3 1.3 1 0 0 1 1 1 1 Zinc knuckle CorA PF01544.18 GBG74249.1 - 1.4 8.2 8.4 2.1 7.6 3.9 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein zf-CCHC_2 PF13696.6 GBG74249.1 - 1.6 8.7 4.3 2.5 8.0 4.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Usp PF00582.26 GBG74250.1 - 3.4e-32 111.9 0.8 1.3e-31 110.0 0.8 1.9 1 1 0 1 1 1 1 Universal stress protein family zf-RING_2 PF13639.6 GBG74251.1 - 3.8e-13 49.5 7.2 5.9e-13 48.9 7.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG74251.1 - 8e-09 35.2 6.9 1.2e-08 34.6 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG74251.1 - 2.4e-08 33.6 1.6 2.4e-08 33.6 1.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 GBG74251.1 - 3.3e-06 26.9 4.3 5.3e-06 26.3 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GBG74251.1 - 6.7e-06 26.3 10.4 2.1e-05 24.7 10.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GBG74251.1 - 1e-05 25.3 5.3 1.6e-05 24.7 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG74251.1 - 9e-05 22.3 5.6 0.00021 21.1 5.5 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG74251.1 - 0.00012 21.9 8.2 0.0011 18.8 8.2 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GBG74251.1 - 0.00052 20.0 4.3 0.002 18.1 4.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GBG74251.1 - 0.00091 19.2 7.9 0.0017 18.3 7.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-HC5HC2H_2 PF13832.6 GBG74251.1 - 0.021 15.0 0.3 0.042 14.0 0.1 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GBG74251.1 - 0.037 14.3 0.5 0.091 13.0 0.2 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.29 GBG74251.1 - 0.071 13.0 4.0 0.13 12.2 4.0 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 GBG74251.1 - 0.08 12.6 2.8 0.15 11.7 2.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GBG74251.1 - 0.11 12.7 3.6 0.2 11.8 3.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 GBG74251.1 - 0.67 10.3 3.2 1.2 9.6 3.2 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 GBG74251.1 - 1.1 9.3 5.5 2.4 8.1 0.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 GBG74251.1 - 1.3 8.9 7.9 4.7 7.1 7.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 GBG74251.1 - 4.1 7.7 5.0 18 5.6 5.0 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain BUD22 PF09073.10 GBG74252.1 - 0.0064 15.9 18.5 0.0077 15.6 18.5 1.1 1 0 0 1 1 1 1 BUD22 Nha1_C PF08619.10 GBG74252.1 - 0.0074 15.5 17.8 0.0088 15.3 17.8 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2201_N PF13203.6 GBG74252.1 - 0.0095 15.6 11.2 0.011 15.3 11.2 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain RPN2_C PF18004.1 GBG74252.1 - 0.012 15.5 17.0 0.016 15.1 17.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Afi1 PF07792.12 GBG74252.1 - 0.014 15.9 9.0 0.019 15.4 9.0 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2052 PF09747.9 GBG74252.1 - 0.055 13.6 20.5 0.087 13.0 20.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SPT6_acidic PF14632.6 GBG74252.1 - 0.074 13.6 2.8 0.074 13.6 2.8 3.1 2 1 0 2 2 1 0 Acidic N-terminal SPT6 Cwf_Cwc_15 PF04889.12 GBG74252.1 - 0.076 12.7 15.7 0.092 12.5 15.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF913 PF06025.12 GBG74252.1 - 0.088 11.8 4.5 0.095 11.7 4.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Caldesmon PF02029.15 GBG74252.1 - 0.1 11.4 25.8 0.14 10.9 25.8 1.2 1 0 0 1 1 1 0 Caldesmon RXT2_N PF08595.11 GBG74252.1 - 0.22 11.5 12.3 0.33 11.0 12.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM60A PF15396.6 GBG74252.1 - 0.23 11.4 3.5 0.28 11.2 3.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A NPR3 PF03666.13 GBG74252.1 - 0.24 10.1 12.3 0.28 9.9 12.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 V_ATPase_I PF01496.19 GBG74252.1 - 0.26 9.2 9.0 0.28 9.1 9.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 GBG74252.1 - 0.34 9.6 9.8 0.39 9.4 9.8 1.0 1 0 0 1 1 1 0 Presenilin FGF-BP1 PF06473.12 GBG74252.1 - 0.36 10.6 9.0 0.45 10.3 9.0 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) FancD2 PF14631.6 GBG74252.1 - 0.44 7.9 6.7 0.47 7.8 6.7 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DNA_pol_phi PF04931.13 GBG74252.1 - 0.44 8.6 25.5 0.44 8.6 25.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.10 GBG74252.1 - 0.47 10.8 13.8 0.6 10.4 13.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.12 GBG74252.1 - 0.47 9.7 18.7 0.64 9.3 18.7 1.2 1 0 0 1 1 1 0 NOA36 protein SLC12 PF03522.15 GBG74252.1 - 0.6 9.1 3.2 0.72 8.8 3.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RNA_pol_3_Rpc31 PF11705.8 GBG74252.1 - 0.69 10.1 28.1 0.98 9.6 28.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Serinc PF03348.15 GBG74252.1 - 1.1 8.1 3.4 1.1 8.1 3.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RRN3 PF05327.11 GBG74252.1 - 1.4 7.4 13.4 1.6 7.2 13.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 D123 PF07065.14 GBG74252.1 - 1.8 7.7 6.3 2 7.5 6.3 1.2 1 0 0 1 1 1 0 D123 Nop14 PF04147.12 GBG74252.1 - 1.9 6.6 27.4 2.4 6.2 27.4 1.1 1 0 0 1 1 1 0 Nop14-like family RAB3GAP2_C PF14656.6 GBG74252.1 - 1.9 6.6 6.1 1.7 6.7 6.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF2828 PF11443.8 GBG74252.1 - 2.6 6.0 8.4 3 5.8 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CAF1 PF04857.20 GBG74252.1 - 2.7 7.1 7.7 2.8 7.0 7.7 1.0 1 0 0 1 1 1 0 CAF1 family ribonuclease PPL5 PF18168.1 GBG74252.1 - 4.2 6.6 6.3 6.3 6.0 6.3 1.4 1 0 0 1 1 1 0 Prim-pol family 5 DUF2151 PF10221.9 GBG74252.1 - 4.6 5.7 7.8 4.7 5.7 7.8 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 GBG74252.1 - 6.2 5.9 7.2 6.8 5.8 7.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Fmp27 PF10344.9 GBG74252.1 - 6.3 4.8 13.1 7.5 4.5 13.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 SDA1 PF05285.12 GBG74252.1 - 6.4 6.1 29.1 9.8 5.5 29.1 1.2 1 0 0 1 1 1 0 SDA1 Dsh_C PF12316.8 GBG74252.1 - 7.7 6.9 5.4 8.2 6.8 5.4 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal MCM_bind PF09739.9 GBG74252.1 - 7.8 4.8 8.9 8.9 4.6 8.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Astro_capsid_p PF12226.8 GBG74252.1 - 9.9 5.2 14.0 11 5.1 14.0 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nicastrin PF05450.15 GBG74253.1 - 1.9e-10 40.6 0.0 2.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 GBG74253.1 - 8.3e-07 28.9 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Radical_SAM_C PF16199.5 GBG74255.1 - 2.2e-31 107.7 0.0 3.7e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Acetyltransf_1 PF00583.25 GBG74255.1 - 1e-09 38.6 0.2 1.8e-09 37.8 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Radical_SAM PF04055.21 GBG74255.1 - 7.6e-08 32.9 0.0 3.6e-07 30.7 0.0 2.2 3 1 0 3 3 3 1 Radical SAM superfamily Acetyltransf_10 PF13673.7 GBG74255.1 - 7.7e-06 25.9 0.1 1.5e-05 24.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GBG74255.1 - 0.001 19.4 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG74255.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Peptidase_S49_N PF08496.10 GBG74257.1 - 0.19 11.8 2.5 0.26 11.3 2.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal COPI_C PF06957.11 GBG74257.1 - 5.9 5.5 9.2 6.7 5.4 9.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CobT PF06213.12 GBG74257.1 - 8.7 5.6 14.2 10 5.4 14.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Myb_DNA-bind_4 PF13837.6 GBG74258.1 - 1.2e-09 38.4 0.9 1.2e-09 38.4 0.9 2.4 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG74258.1 - 0.15 12.4 0.4 0.39 11.1 0.4 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF659 PF04937.15 GBG74259.1 - 8.3e-08 32.2 0.1 6.6e-07 29.3 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) Myb_DNA-binding PF00249.31 GBG74260.1 - 1.9e-13 50.4 0.2 5.5e-06 26.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG74260.1 - 2.8e-09 37.1 0.0 0.0016 18.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG74260.1 - 0.091 13.2 1.0 0.54 10.7 0.1 2.6 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG74260.1 - 0.16 12.3 0.1 10 6.5 0.0 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FAM60A PF15396.6 GBG74260.1 - 0.38 10.7 3.4 6.3 6.7 0.1 2.6 2 1 1 3 3 3 0 Protein Family FAM60A CDV3 PF15359.6 GBG74260.1 - 1.7 9.2 5.1 16 6.0 0.3 2.4 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF2232 PF09991.9 GBG74261.1 - 3.1e-12 46.3 15.3 2.1e-11 43.5 15.3 2.0 1 1 0 1 1 1 1 Predicted membrane protein (DUF2232) DUF4267 PF14087.6 GBG74261.1 - 0.36 10.9 5.1 1.2 9.3 5.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) SDA1 PF05285.12 GBG74264.1 - 0.0011 18.5 49.8 0.0014 18.1 49.8 1.2 1 0 0 1 1 1 1 SDA1 LAP1C PF05609.12 GBG74264.1 - 0.13 11.3 20.0 0.16 11.1 20.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 GBG74264.1 - 0.24 10.1 22.8 0.28 9.9 22.8 1.1 1 0 0 1 1 1 0 Presenilin DUF262 PF03235.14 GBG74264.1 - 0.36 11.0 17.0 0.48 10.6 17.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 SLC12 PF03522.15 GBG74264.1 - 3.7 6.5 19.3 4.6 6.1 19.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LTV PF04180.14 GBG74264.1 - 4.1 7.0 34.0 6.2 6.4 34.0 1.3 1 0 0 1 1 1 0 Low temperature viability protein DUF4045 PF13254.6 GBG74264.1 - 5 6.7 20.7 6.7 6.2 20.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAPS PF04499.15 GBG74264.1 - 6.6 5.4 26.9 7.5 5.2 26.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pkinase_Tyr PF07714.17 GBG74265.1 - 4.8e-55 186.6 0.0 6.6e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG74265.1 - 3.3e-52 177.5 0.0 4.3e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG74265.1 - 2.9e-05 24.1 0.1 0.00022 21.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Leu_zip PF15294.6 GBG74265.1 - 0.0053 16.3 0.0 0.0075 15.8 0.0 1.1 1 0 0 1 1 1 1 Leucine zipper Haspin_kinase PF12330.8 GBG74265.1 - 0.019 14.0 0.0 0.08 11.9 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 GBG74265.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 GBG74265.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 1 0 1 1 1 0 Kinase-like ZapB PF06005.12 GBG74265.1 - 0.21 12.0 2.0 0.42 11.1 2.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB UQ_con PF00179.26 GBG74266.1 - 3.9e-43 146.5 0.0 4.4e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GBG74266.1 - 0.063 13.0 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Kinetochor_Ybp2 PF08568.10 GBG74267.1 - 5.4e-19 68.1 0.0 3.9e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin PTPRCAP PF15713.5 GBG74267.1 - 0.0065 16.8 2.1 0.0065 16.8 2.1 2.3 2 0 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated TFIIA PF03153.13 GBG74267.1 - 0.017 15.1 5.2 0.029 14.4 5.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF659 PF04937.15 GBG74268.1 - 3.9e-32 111.2 0.2 6.4e-32 110.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG74269.1 - 2e-19 69.8 0.0 4.4e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74269.1 - 8.1e-18 64.3 0.0 1.7e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74269.1 - 2e-11 43.8 0.3 5.5e-11 42.4 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG74269.1 - 6.7e-07 29.8 0.0 2.1e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG74269.1 - 0.00013 22.1 0.0 0.00041 20.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG74269.1 - 0.00021 21.9 0.0 0.00054 20.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG74269.1 - 0.00038 20.0 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG74269.1 - 0.0069 16.2 0.8 0.018 14.8 0.5 1.8 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.10 GBG74269.1 - 0.024 14.9 0.8 0.074 13.3 0.8 2.0 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 GBG74269.1 - 0.058 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_M24 PF00557.24 GBG74270.1 - 4.7e-50 170.2 0.1 5.7e-50 169.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 GBG74270.1 - 7.3e-15 55.0 8.1 1.5e-14 54.0 8.1 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 GBG74270.1 - 1.3e-05 25.2 6.7 1.3e-05 25.2 6.7 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 GBG74270.1 - 0.0004 20.2 6.4 0.00076 19.3 6.4 1.4 1 0 0 1 1 1 1 HIT zinc finger GIDA PF01134.22 GBG74271.1 - 5.7e-153 509.6 0.0 7.2e-153 509.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 GBG74271.1 - 1.5e-68 231.2 0.7 2.1e-68 230.6 0.7 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 GBG74271.1 - 8.3e-09 35.3 1.0 2.1e-08 34.0 0.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GBG74271.1 - 2.9e-06 26.7 0.1 8.5e-06 25.2 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GBG74271.1 - 9.1e-05 21.7 1.7 9.1e-05 21.7 1.7 2.5 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 GBG74271.1 - 0.0011 18.3 0.5 0.0011 18.3 0.5 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GBG74271.1 - 0.0018 18.8 0.1 0.0073 16.8 0.1 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG74271.1 - 0.0092 14.7 1.6 0.058 12.1 0.4 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 GBG74271.1 - 0.029 13.6 0.3 0.13 11.5 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GBG74271.1 - 0.11 12.1 5.4 0.18 11.3 0.5 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GBG74271.1 - 0.6 10.4 2.8 5.5 7.3 1.3 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain BPL_LplA_LipB PF03099.19 GBG74272.1 - 1.5e-09 37.9 0.0 2.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF659 PF04937.15 GBG74273.1 - 1.8e-15 57.1 0.0 2.5e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Glyco_trans_2_3 PF13632.6 GBG74274.1 - 1.9e-34 119.3 17.7 4.8e-20 72.3 5.0 3.9 4 2 1 5 5 5 2 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GBG74274.1 - 2.4e-26 93.1 1.4 2.3e-12 47.3 0.1 3.5 3 0 0 3 3 3 3 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 GBG74274.1 - 4.9e-24 84.9 17.4 2.3e-08 33.1 2.2 4.4 3 2 2 5 5 5 3 Cellulose synthase Glyco_transf_21 PF13506.6 GBG74274.1 - 3.3e-16 59.2 0.0 2.9e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GBG74274.1 - 4.5e-13 49.4 0.0 2.5e-06 27.4 0.0 3.4 3 0 0 3 3 3 2 Glycosyl transferase family 2 Cytochrome-c551 PF10643.9 GBG74274.1 - 0.13 11.8 4.2 6.5 6.3 0.3 2.4 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Endotoxin_N PF03945.14 GBG74274.1 - 0.16 11.7 0.1 22 4.7 0.0 2.2 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain Pro_isomerase PF00160.21 GBG74275.1 - 2.6e-32 112.3 0.4 6.2e-17 62.3 0.0 3.1 2 1 1 3 3 3 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RVT_1 PF00078.27 GBG74275.1 - 4.7e-22 78.6 0.1 8.7e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74276.1 - 3.2e-27 94.5 0.0 5.1e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74276.1 - 2e-26 92.3 0.0 3.1e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74276.1 - 3e-14 53.1 0.0 4.9e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG74276.1 - 0.043 13.7 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Trypan_PARP PF05887.11 GBG74277.1 - 0.51 10.3 8.7 0.51 10.3 8.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LRR_8 PF13855.6 GBG74278.1 - 3.1e-26 90.9 17.7 1.8e-08 34.0 0.1 3.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GBG74278.1 - 8.8e-23 80.0 3.5 8.5e-05 22.8 0.0 4.6 2 2 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG74278.1 - 2.2e-06 27.4 3.4 2.4 9.0 0.1 6.4 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 GBG74278.1 - 0.009 16.0 5.8 3.8 7.8 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeat RsmF_methylt_CI PF17126.5 GBG74278.1 - 0.05 13.7 0.1 29 4.8 0.0 3.0 2 1 1 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain RT_RNaseH_2 PF17919.1 GBG74279.1 - 1.1e-35 121.7 0.1 1.9e-35 120.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74279.1 - 2.6e-32 111.2 0.0 5.6e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG74279.1 - 2.2e-08 33.8 1.2 4.2e-08 32.9 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG74279.1 - 1.2e-06 28.7 0.1 2.7e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG74279.1 - 0.018 14.8 2.7 0.044 13.6 2.7 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF866 PF05907.13 GBG74280.1 - 2.3e-50 170.5 0.0 2.6e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zinc_ribbon_6 PF14599.6 GBG74280.1 - 0.2 11.7 3.0 1 9.4 0.2 2.8 3 0 0 3 3 3 0 Zinc-ribbon zf-NADH-PPase PF09297.11 GBG74280.1 - 0.48 10.1 3.2 18 5.1 0.9 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain EF-hand_6 PF13405.6 GBG74281.1 - 1.5e-08 33.9 0.8 0.00072 19.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 GBG74281.1 - 9.3e-07 28.0 0.7 0.0024 17.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GBG74281.1 - 2.7e-06 27.7 1.9 0.029 14.8 0.4 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG74281.1 - 9.2e-06 24.9 0.8 0.03 13.8 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 GBG74281.1 - 0.018 14.9 0.5 3.5 7.6 0.1 2.4 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 GBG74281.1 - 0.046 14.0 0.2 8.3 6.8 0.1 2.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 GBG74281.1 - 0.058 13.3 0.1 19 5.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair RT_RNaseH_2 PF17919.1 GBG74283.1 - 2.2e-33 114.2 0.0 4.5e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74283.1 - 2.4e-28 98.5 0.1 4.9e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74283.1 - 1.1e-27 97.0 0.2 1.7e-27 96.4 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74283.1 - 5.7e-19 68.0 0.2 1.4e-18 66.7 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG74283.1 - 0.033 14.4 0.0 0.16 12.2 0.0 2.3 1 0 0 1 1 1 0 H2C2 zinc finger SapB_1 PF05184.15 GBG74283.1 - 3.3 7.8 4.3 1.3 9.1 0.2 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 1 Acetyltransf_1 PF00583.25 GBG74284.1 - 2.6e-15 56.7 0.0 4.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GBG74284.1 - 9.1e-08 32.1 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GBG74284.1 - 1.8e-07 31.4 0.0 3.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG74284.1 - 2e-05 24.5 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GBG74284.1 - 0.0049 17.6 0.0 0.0074 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RVT_1 PF00078.27 GBG74285.1 - 1.5e-30 106.4 0.0 2.4e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_H_Exchanger PF00999.21 GBG74286.1 - 9.5e-59 199.1 39.9 1.4e-58 198.5 39.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family WD40 PF00400.32 GBG74288.1 - 4.5e-12 46.3 14.1 1.2e-06 29.1 0.4 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG74288.1 - 4.8e-08 33.2 4.9 0.0001 22.5 0.2 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain K_channel_TID PF07941.11 GBG74288.1 - 0.0023 18.3 4.3 0.0023 18.3 4.3 6.7 6 1 0 6 6 6 1 Potassium channel Kv1.4 tandem inactivation domain GRP PF07172.11 GBG74288.1 - 0.0034 18.0 13.3 0.0034 18.0 13.3 7.3 4 2 0 4 4 4 1 Glycine rich protein family ETRAMP PF09716.10 GBG74288.1 - 0.019 15.0 0.5 0.019 15.0 0.5 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) eIF2A PF08662.11 GBG74288.1 - 0.06 13.2 3.6 0.038 13.9 0.7 2.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A SR-25 PF10500.9 GBG74288.1 - 0.13 11.8 39.0 0.074 12.7 22.2 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DPPIV_N PF00930.21 GBG74288.1 - 0.13 11.0 0.7 3.4 6.3 0.1 2.3 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region GEN1_C PF18380.1 GBG74288.1 - 0.56 11.1 11.1 1.6 9.7 2.0 3.5 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain Peptidase_S49_N PF08496.10 GBG74288.1 - 4.2 7.4 10.7 9.3 6.3 10.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal gag-asp_proteas PF13975.6 GBG74289.1 - 5.8e-07 30.0 0.0 3.1e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74289.1 - 2.2e-06 28.2 0.0 1.8e-05 25.3 0.0 2.6 3 0 0 3 3 3 1 Aspartyl protease RVP_2 PF08284.11 GBG74289.1 - 1e-05 25.3 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG74289.1 - 0.088 13.1 0.9 1.5 9.2 0.0 3.2 3 0 0 3 3 3 0 Retrotransposon gag protein GCIP PF13324.6 GBG74289.1 - 2.8 7.5 6.5 6.1 6.4 6.5 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting HTH_Tnp_Mu_1 PF02316.16 GBG74290.1 - 0.09 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Mu DNA-binding domain FAM199X PF15814.5 GBG74290.1 - 0.13 11.3 3.6 0.21 10.6 3.6 1.3 1 0 0 1 1 1 0 Protein family FAM199X GIY-YIG PF01541.24 GBG74290.1 - 0.15 12.4 0.0 0.51 10.6 0.0 2.0 1 0 0 1 1 1 0 GIY-YIG catalytic domain DUF659 PF04937.15 GBG74292.1 - 1.7e-16 60.4 0.0 4.7e-16 59.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG74292.1 - 0.0042 16.9 0.3 0.0097 15.7 0.3 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region REF PF05755.12 GBG74293.1 - 5.3e-14 52.5 0.2 8.9e-14 51.8 0.2 1.3 1 0 0 1 1 1 1 Rubber elongation factor protein (REF) LRAT PF04970.13 GBG74294.1 - 3.7e-16 59.6 1.1 1.1e-08 35.4 0.0 2.4 2 0 0 2 2 2 2 Lecithin retinol acyltransferase Sde2_N_Ubi PF13019.6 GBG74294.1 - 0.17 11.7 1.2 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain PIP5K PF01504.18 GBG74295.1 - 1.2e-85 287.1 0.0 2.6e-85 286.0 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MORN PF02493.20 GBG74295.1 - 6.7e-41 135.8 58.2 6.9e-07 28.8 0.6 9.1 9 0 0 9 9 9 8 MORN repeat RT_RNaseH PF17917.1 GBG74296.1 - 1.8e-13 50.7 0.3 4e-13 49.5 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG74296.1 - 3.1e-06 27.0 0.0 7.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG74296.1 - 1.1e-05 25.3 0.0 3.3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74296.1 - 2.1e-05 25.1 0.0 8.6e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74296.1 - 0.00086 19.8 0.0 0.0053 17.3 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG74296.1 - 0.0095 16.2 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG74296.1 - 0.08 12.7 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease DNA_pol_phi PF04931.13 GBG74297.1 - 0.0013 16.9 21.5 0.0013 16.9 21.5 4.0 2 1 1 3 3 3 1 DNA polymerase phi Chloroa_b-bind PF00504.21 GBG74298.1 - 0.00019 22.0 0.2 0.02 15.4 0.1 2.0 1 1 1 2 2 2 2 Chlorophyll A-B binding protein 3Beta_HSD PF01073.19 GBG74299.1 - 1.9e-31 109.1 0.0 1.7e-12 46.9 0.0 3.4 4 0 0 4 4 4 3 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4499 PF14934.6 GBG74299.1 - 1.8e-16 60.2 2.7 3.7e-16 59.2 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Epimerase PF01370.21 GBG74299.1 - 1.6e-11 44.2 0.0 0.0001 21.9 0.0 3.3 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family zf-GRF PF06839.12 GBG74299.1 - 7.5e-07 29.1 0.6 2.4e-06 27.5 0.6 1.9 1 0 0 1 1 1 1 GRF zinc finger NmrA PF05368.13 GBG74299.1 - 5.1e-05 22.9 0.0 8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GBG74299.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Exo_endo_phos PF03372.23 GBG74299.1 - 0.0053 16.3 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-HC3 PF16827.5 GBG74299.1 - 0.19 11.9 1.7 0.4 10.9 0.9 2.0 1 1 0 1 1 1 0 zinc-finger GATase_2 PF00310.21 GBG74300.1 - 7.1e-176 585.0 0.0 9.9e-176 584.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GBG74300.1 - 6.2e-151 502.7 0.1 1.2e-150 501.7 0.1 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GBG74300.1 - 3.4e-111 371.2 0.0 1.7e-110 368.9 0.0 1.9 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GBG74300.1 - 2.7e-84 281.5 5.1 4.4e-84 280.8 5.1 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 GBG74300.1 - 1.3e-25 90.3 0.1 3.7e-25 88.7 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 GBG74300.1 - 2e-21 75.9 0.2 2e-21 75.9 0.2 1.9 2 0 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 GBG74300.1 - 2.3e-08 34.1 0.1 6.5e-07 29.5 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GBG74300.1 - 1.8e-06 27.5 0.4 0.35 10.1 0.0 3.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GBG74300.1 - 3.1e-06 27.0 0.4 0.0037 16.9 0.1 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GBG74300.1 - 9.4e-06 26.1 2.5 0.0027 18.2 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GBG74300.1 - 6.3e-05 22.4 0.7 9.8e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GBG74300.1 - 0.00074 18.7 0.3 0.0082 15.3 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 GBG74300.1 - 0.00079 19.8 0.4 0.99 9.9 0.1 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.14 GBG74300.1 - 0.0011 17.7 0.3 0.0011 17.7 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 GBG74300.1 - 0.0016 17.9 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.19 GBG74300.1 - 0.0021 16.6 0.3 0.46 8.8 0.0 3.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 GBG74300.1 - 0.006 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 GBG74300.1 - 0.012 14.7 1.0 0.42 9.6 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GBG74300.1 - 0.022 14.1 0.6 4.9 6.4 0.1 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GBG74300.1 - 0.026 13.7 0.1 0.069 12.4 0.1 1.7 1 0 0 1 1 1 0 Thi4 family FMN_dh PF01070.18 GBG74300.1 - 0.07 12.2 0.5 0.17 10.9 0.5 1.6 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Luciferase_cat PF10285.9 GBG74300.1 - 0.16 11.4 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Luciferase catalytic domain RT_RNaseH_2 PF17919.1 GBG74301.1 - 8.8e-25 86.7 0.0 1.9e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74301.1 - 1.1e-22 80.3 0.0 2.5e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74301.1 - 2.9e-14 53.1 0.0 6.7e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG74301.1 - 3.7e-06 27.4 0.0 1.2e-05 25.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74301.1 - 1.3e-05 25.7 0.0 6.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG74301.1 - 0.00048 19.9 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease ApoLp-III PF07464.11 GBG74301.1 - 0.00088 19.4 4.5 0.0018 18.4 4.5 1.4 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Asp_protease PF09668.10 GBG74301.1 - 0.002 17.9 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74301.1 - 0.052 13.8 6.0 0.11 12.8 0.3 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein DUF3552 PF12072.8 GBG74301.1 - 0.075 12.4 0.6 0.14 11.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4446 PF14584.6 GBG74301.1 - 0.27 11.2 1.4 2.2 8.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Apolipoprotein PF01442.18 GBG74301.1 - 0.45 10.4 4.0 0.68 9.8 2.4 2.0 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain RVT_1 PF00078.27 GBG74302.1 - 1.4e-38 132.7 0.0 1.2e-20 74.0 0.0 2.8 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG74302.1 - 1.3e-09 38.2 0.9 1.3e-09 38.2 0.9 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG74302.1 - 5.7e-08 32.7 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG74302.1 - 0.014 15.2 0.0 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74302.1 - 0.037 14.7 0.0 0.73 10.5 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease RNA_polI_A34 PF08208.11 GBG74302.1 - 0.061 13.4 3.4 0.13 12.3 3.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Sigma70_ner PF04546.13 GBG74302.1 - 0.11 12.3 7.7 0.061 13.2 2.4 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.12 GBG74302.1 - 0.12 11.7 7.9 0.3 10.3 7.9 1.7 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 GBG74302.1 - 0.83 9.2 12.0 2.4 7.7 12.0 1.8 1 0 0 1 1 1 0 PPP4R2 UBA PF00627.31 GBG74304.1 - 2e-08 34.0 0.0 5.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 GBG74304.1 - 4.2e-06 26.8 9.3 7.6e-06 26.0 8.8 1.6 1 1 1 2 2 2 2 Rhomboid family DER1 PF04511.15 GBG74304.1 - 0.0013 18.7 3.0 0.0018 18.2 3.0 1.3 1 0 0 1 1 1 1 Der1-like family GXGXG PF01493.19 GBG74306.1 - 1.7e-33 115.8 1.3 3.2e-33 114.9 1.3 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 GBG74306.1 - 4.4e-26 91.8 0.1 1.1e-25 90.5 0.1 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 GBG74306.1 - 1.1e-21 76.7 0.1 2e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_3 PF13738.6 GBG74306.1 - 6e-10 38.9 0.7 0.054 12.8 0.1 4.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GBG74306.1 - 1.6e-09 37.9 0.0 2.9e-08 33.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG74306.1 - 2.3e-07 30.8 0.5 0.00097 18.8 0.3 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GBG74306.1 - 7.9e-07 28.7 0.5 4.2e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 GBG74306.1 - 2.1e-06 28.2 7.3 0.00011 22.6 0.6 3.6 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GBG74306.1 - 1.7e-05 24.1 2.2 0.00049 19.3 0.6 3.2 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 GBG74306.1 - 5.2e-05 22.1 4.2 0.00013 20.8 0.4 2.9 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 GBG74306.1 - 0.00028 20.3 0.0 0.00028 20.3 0.0 1.6 2 0 0 2 2 1 1 FAD binding domain Thi4 PF01946.17 GBG74306.1 - 0.00034 19.9 1.3 0.00048 19.4 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 GBG74306.1 - 0.00038 19.9 0.1 0.00038 19.9 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GBG74306.1 - 0.00038 19.6 2.1 0.062 12.4 0.3 3.0 2 1 1 3 3 3 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 GBG74306.1 - 0.00082 19.8 1.2 1.7 9.1 0.2 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 GBG74306.1 - 0.0011 18.3 0.8 0.49 9.7 0.0 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 GBG74306.1 - 0.013 14.0 1.0 0.87 7.9 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Rossmann-like PF10727.9 GBG74306.1 - 0.061 13.2 1.2 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 Rossmann-like domain F420_oxidored PF03807.17 GBG74306.1 - 0.15 12.6 2.5 28 5.4 0.1 4.4 5 0 0 5 5 4 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 GBG74306.1 - 0.16 11.9 1.0 3.3 7.7 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.21 GBG74306.1 - 1.3 9.0 4.4 0.99 9.5 0.1 2.6 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase_2 PF00310.21 GBG74307.1 - 1.6e-179 597.0 0.0 2.5e-179 596.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GBG74307.1 - 8.2e-152 505.6 0.8 1.5e-151 504.7 0.4 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GBG74307.1 - 1.1e-114 382.7 0.0 2.3e-113 378.3 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GBG74307.1 - 1.8e-42 145.1 0.1 2.9e-42 144.4 0.1 1.4 1 0 0 1 1 1 1 GXGXG motif RVT_1 PF00078.27 GBG74308.1 - 1.7e-29 102.9 0.0 2.6e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74308.1 - 2.5e-21 75.6 0.0 6.2e-16 58.3 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74308.1 - 1.6e-09 38.0 0.0 4.2e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74308.1 - 0.023 15.4 0.0 0.063 13.9 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease DUF1138 PF06592.13 GBG74309.1 - 4.7e-22 77.8 0.2 5.1e-22 77.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1138) COX4 PF02936.14 GBG74309.1 - 5.2e-05 23.3 0.1 5.9e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1138 PF06592.13 GBG74310.1 - 5.9e-22 77.5 0.0 6.5e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1138) COX4 PF02936.14 GBG74310.1 - 0.00043 20.3 0.0 0.00048 20.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV RTT107_BRCT_5 PF16770.5 GBG74311.1 - 6.8e-09 35.5 0.0 2.5e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 GBG74311.1 - 2.9e-06 27.6 0.0 3.5e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GBG74311.1 - 5.5e-06 26.7 0.0 0.0034 17.8 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain zf-CCHC PF00098.23 GBG74313.1 - 7.7e-06 25.7 3.2 1.6e-05 24.8 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG74313.1 - 0.0065 16.7 0.0 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG74313.1 - 0.54 10.1 10.9 0.031 14.1 4.1 2.2 2 0 0 2 2 2 0 Zinc knuckle Na_trans_assoc PF06512.13 GBG74313.1 - 0.66 10.2 11.4 1.2 9.3 11.4 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG74313.1 - 1.3 8.3 18.4 2.2 7.6 18.4 1.2 1 0 0 1 1 1 0 SDA1 DUF4746 PF15928.5 GBG74313.1 - 2.4 7.5 11.9 4.4 6.6 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 GBG74313.1 - 3.7 5.6 18.6 5.6 5.0 18.6 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.6 GBG74313.1 - 3.8 7.0 8.2 8 6.0 8.2 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop53 PF07767.11 GBG74313.1 - 7.6 5.8 18.1 13 5.1 18.1 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FKBP_C PF00254.28 GBG74314.1 - 4.3e-31 107.1 0.0 1e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Utp14 PF04615.13 GBG74314.1 - 2.4 6.7 43.0 3.5 6.1 43.0 1.2 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 GBG74314.1 - 8.2 4.8 16.2 10 4.5 16.2 1.2 1 0 0 1 1 1 0 Macoilin family Ribonuclease_3 PF00636.26 GBG74315.1 - 3.6e-12 46.8 0.0 6.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain LRR_6 PF13516.6 GBG74316.1 - 0.041 14.0 10.3 15 6.0 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich repeat DDHD PF02862.17 GBG74316.1 - 0.28 11.3 2.8 0.73 10.0 0.3 2.3 2 0 0 2 2 2 0 DDHD domain LRR_1 PF00560.33 GBG74316.1 - 0.51 11.1 2.6 50 5.0 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 GBG74316.1 - 1.2 9.0 6.4 0.22 11.3 1.4 2.3 2 1 1 3 3 3 0 Leucine rich repeat Nop14 PF04147.12 GBG74316.1 - 1.3 7.1 21.4 1.9 6.6 21.4 1.2 1 0 0 1 1 1 0 Nop14-like family LRR_4 PF12799.7 GBG74316.1 - 4.4 7.9 6.5 9.2 6.8 4.0 2.7 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Ribosomal_S17 PF00366.20 GBG74317.1 - 1.2e-29 102.2 3.0 1.7e-29 101.7 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 RT_RNaseH_2 PF17919.1 GBG74318.1 - 4.8e-29 100.3 0.0 1.1e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74318.1 - 8.6e-29 99.9 0.0 1.7e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74318.1 - 1.7e-18 66.5 0.1 3.7e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74318.1 - 1.7e-16 60.5 0.0 3.9e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74318.1 - 0.0016 18.6 0.0 0.0045 17.2 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF4828 PF16110.5 GBG74319.1 - 0.092 13.2 0.0 0.1 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4828) RRN3 PF05327.11 GBG74320.1 - 0.00048 18.8 2.1 0.00066 18.3 2.1 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GBG74320.1 - 0.062 11.6 10.6 0.084 11.2 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 GBG74320.1 - 4.7 6.3 7.2 9 5.3 7.2 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 GBG74320.1 - 7 4.7 12.8 9.5 4.3 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family Sel1 PF08238.12 GBG74321.1 - 1.8e-86 282.6 53.1 3.7e-10 40.1 1.2 13.0 12 1 0 12 12 12 11 Sel1 repeat DDE_Tnp_4 PF13359.6 GBG74321.1 - 1.8e-09 37.5 0.0 3.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_7 PF13176.6 GBG74321.1 - 0.042 13.9 12.1 5.9 7.1 0.2 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG74321.1 - 0.26 12.0 20.0 4 8.3 0.1 7.7 9 0 0 9 9 7 0 Tetratricopeptide repeat Radial_spoke PF04712.12 GBG74321.1 - 0.37 9.7 11.5 0.59 9.0 11.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein TFIIA PF03153.13 GBG74321.1 - 0.52 10.3 10.5 0.97 9.4 10.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 GBG74321.1 - 0.63 8.1 8.1 1.4 6.9 8.1 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PPP4R2 PF09184.11 GBG74321.1 - 2.4 7.7 11.8 4.6 6.7 11.8 1.4 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GBG74321.1 - 2.5 6.2 20.0 3.7 5.6 20.0 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG74321.1 - 3.7 6.8 12.7 9.1 5.5 12.7 1.6 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.9 GBG74321.1 - 4.4 5.0 9.8 6.9 4.3 9.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TPR_11 PF13414.6 GBG74321.1 - 7.4 6.3 16.9 6.5 6.5 0.0 5.3 6 0 0 6 6 6 0 TPR repeat SDA1 PF05285.12 GBG74321.1 - 7.7 5.8 23.9 0.39 10.1 16.4 2.1 2 0 0 2 2 2 0 SDA1 Na_trans_cytopl PF11933.8 GBG74321.1 - 8.1 6.2 12.8 1.1 9.1 6.6 2.1 2 0 0 2 2 2 0 Cytoplasmic domain of voltage-gated Na+ ion channel DUF308 PF03729.13 GBG74322.1 - 0.38 11.1 26.6 1.8 8.9 5.1 3.5 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DNA_pol3_tau_4 PF12168.8 GBG74322.1 - 1.3 9.6 5.9 0.19 12.3 1.1 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding FAM176 PF14851.6 GBG74322.1 - 2.9 7.5 7.9 12 5.6 0.9 3.3 3 0 0 3 3 3 0 FAM176 family DDE_Tnp_4 PF13359.6 GBG74324.1 - 1.7e-34 118.8 0.1 2.7e-33 114.9 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74324.1 - 3.7e-18 65.9 0.0 6.7e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG74324.1 - 0.0043 17.4 0.7 0.062 13.7 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG74324.1 - 0.006 16.2 1.1 2.4 7.8 0.1 3.0 3 0 0 3 3 3 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG74326.1 - 3.2e-07 30.6 1.8 3.1e-06 27.5 0.5 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Dus PF01207.17 GBG74327.1 - 1.5e-54 185.2 0.2 3.4e-54 184.0 0.2 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.18 GBG74327.1 - 0.017 14.2 0.1 0.029 13.4 0.1 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Amidohydro_2 PF04909.14 GBG74327.1 - 0.052 13.3 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Amidohydrolase His_biosynth PF00977.21 GBG74327.1 - 0.089 12.2 0.1 0.17 11.3 0.1 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein DUF913 PF06025.12 GBG74327.1 - 0.17 10.8 4.0 0.24 10.3 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GBG74327.1 - 6.6 5.4 12.2 9.9 4.8 12.2 1.1 1 0 0 1 1 1 0 Presenilin Mur_ligase_M PF08245.12 GBG74328.1 - 1.4e-07 31.7 0.0 4.2e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 Mur ligase middle domain RVT_1 PF00078.27 GBG74329.1 - 8.1e-10 38.6 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74329.1 - 0.054 13.5 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG74329.1 - 3 6.0 10.7 4.1 5.6 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG74329.1 - 4.6 6.6 12.1 6.2 6.1 12.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG74329.1 - 4.6 5.3 10.7 5.9 5.0 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family gag-asp_proteas PF13975.6 GBG74330.1 - 2.5e-08 34.4 1.4 1.2e-06 29.0 0.0 3.2 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74330.1 - 0.0021 18.7 1.0 0.023 15.3 0.0 2.7 3 0 0 3 3 3 1 Aspartyl protease RVP PF00077.20 GBG74330.1 - 0.024 15.0 0.0 0.28 11.5 0.0 2.5 1 1 0 1 1 1 0 Retroviral aspartyl protease bZIP_1 PF00170.21 GBG74331.1 - 1.4e-12 47.5 7.2 3.1e-12 46.4 7.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG74331.1 - 5.4e-05 23.2 6.3 0.00017 21.6 6.3 1.8 1 1 0 1 1 1 1 Basic region leucine zipper CCDC66 PF15236.6 GBG74332.1 - 0.23 11.3 18.3 0.49 10.2 18.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DUF2514 PF10721.9 GBG74332.1 - 0.3 11.1 7.6 0.48 10.4 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Presenilin PF01080.17 GBG74332.1 - 5.8 5.6 4.5 7.1 5.3 4.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4337 PF14235.6 GBG74332.1 - 6.8 6.8 9.1 11 6.1 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) VIT1 PF01988.19 GBG74332.1 - 8.5 6.2 8.1 15 5.4 8.1 1.5 1 1 0 1 1 1 0 VIT family G6PD_C PF02781.16 GBG74333.1 - 1e-56 192.3 0.0 1.3e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GBG74334.1 - 1.3e-57 195.3 0.0 1.6e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 GBG74334.1 - 9.7e-16 57.8 0.1 1.4e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Gp_dh_C PF02800.20 GBG74335.1 - 1.2e-69 232.9 0.0 1.6e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG74335.1 - 1.9e-38 130.9 0.0 4.6e-38 129.6 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG74335.1 - 0.0059 16.7 0.3 0.017 15.2 0.0 2.0 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Radical_SAM PF04055.21 GBG74335.1 - 0.15 12.4 0.0 1.4 9.3 0.0 2.0 2 0 0 2 2 2 0 Radical SAM superfamily RVT_1 PF00078.27 GBG74336.1 - 2e-23 83.1 0.0 3.6e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG74336.1 - 0.00023 21.8 2.0 0.00023 21.8 2.0 2.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase IBB PF01749.20 GBG74336.1 - 0.048 14.1 1.4 0.22 12.0 1.4 2.2 1 0 0 1 1 1 0 Importin beta binding domain Gp_dh_C PF02800.20 GBG74337.1 - 5.4e-71 237.3 0.0 7.2e-71 236.9 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG74337.1 - 1.2e-38 131.5 0.0 5e-38 129.5 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG74337.1 - 0.0062 16.7 0.3 0.018 15.1 0.0 2.0 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Radical_SAM PF04055.21 GBG74337.1 - 0.15 12.4 0.0 1.5 9.2 0.0 2.0 2 0 0 2 2 2 0 Radical SAM superfamily RVT_1 PF00078.27 GBG74338.1 - 3.8e-22 78.9 0.1 7.2e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG74338.1 - 0.00072 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74338.1 - 0.017 14.9 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG74338.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Gp_dh_C PF02800.20 GBG74339.1 - 2e-69 232.2 0.0 2.9e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG74339.1 - 3.2e-38 130.1 0.0 9.1e-38 128.7 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG74339.1 - 0.0099 16.0 0.0 0.03 14.4 0.0 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Radical_SAM PF04055.21 GBG74339.1 - 0.082 13.3 0.0 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 Radical SAM superfamily Gp_dh_C PF02800.20 GBG74340.1 - 2.1e-43 147.7 0.0 1.4e-25 89.7 0.0 2.2 1 1 1 2 2 2 2 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG74340.1 - 1.4e-38 131.3 0.0 3.8e-38 129.9 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG74340.1 - 0.0043 17.2 0.4 0.015 15.4 0.0 2.2 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 GBG74340.1 - 0.069 13.0 0.3 4.8 7.0 0.0 2.7 3 0 0 3 3 3 0 NAD(P)H-binding Gp_dh_N PF00044.24 GBG74341.1 - 4.3e-22 78.3 0.0 4.8e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG74341.1 - 0.0012 19.0 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 GBG74341.1 - 0.042 13.2 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phage_head_chap PF11113.8 GBG74341.1 - 0.044 13.9 0.2 0.06 13.4 0.2 1.2 1 0 0 1 1 1 0 Head assembly gene product Gp_dh_N PF00044.24 GBG74342.1 - 3.3e-23 81.9 0.0 3.7e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG74342.1 - 0.0013 18.8 0.0 0.0013 18.8 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 GBG74342.1 - 0.055 12.8 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_4 PF01063.19 GBG74343.1 - 4.5e-34 118.2 0.0 9.9e-32 110.6 0.0 2.1 2 0 0 2 2 2 2 Amino-transferase class IV Gp_dh_C PF02800.20 GBG74344.1 - 1.4e-68 229.4 0.0 1.9e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG74344.1 - 1.4e-38 131.3 0.0 4.3e-38 129.7 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG74344.1 - 0.0058 16.8 0.1 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 GBG74344.1 - 0.068 13.1 0.1 1.8 8.4 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H-binding F-box-like PF12937.7 GBG74346.1 - 1.1e-09 38.0 0.7 2.2e-09 37.1 0.7 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG74346.1 - 2.2e-07 30.6 0.5 4.4e-07 29.6 0.5 1.5 1 0 0 1 1 1 1 F-box domain SelP_N PF04592.14 GBG74346.1 - 0.0037 16.7 13.4 0.0037 16.7 13.4 5.9 2 1 4 6 6 6 1 Selenoprotein P, N terminal region RT_RNaseH_2 PF17919.1 GBG74347.1 - 9.6e-21 73.7 0.0 2e-20 72.7 0.0 1.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74347.1 - 1.6e-18 66.9 0.0 3.5e-18 65.8 0.0 1.5 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74347.1 - 3.3e-14 52.9 0.1 4.9e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG74348.1 - 0.00016 21.8 1.3 0.00034 20.8 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG74348.1 - 0.028 14.3 0.6 0.054 13.4 0.0 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Inhibitor_I29 PF08246.12 GBG74348.1 - 0.14 12.6 0.1 0.37 11.2 0.1 1.7 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) NT-C2 PF10358.9 GBG74349.1 - 3.4e-14 52.8 0.0 8.3e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF745 PF05335.13 GBG74349.1 - 0.00055 19.7 11.0 0.00055 19.7 11.0 14.7 10 5 6 16 16 16 1 Protein of unknown function (DUF745) Fez1 PF06818.15 GBG74349.1 - 0.0066 16.9 10.6 0.0066 16.9 10.6 13.3 5 3 10 15 15 15 4 Fez1 TAFH PF07531.14 GBG74349.1 - 0.39 10.9 6.6 2.1 8.5 0.0 5.1 4 0 0 4 4 4 0 NHR1 homology to TAF DUF4250 PF14056.6 GBG74349.1 - 7.5 6.6 11.5 7.3 6.6 0.4 5.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) DDE_Tnp_4 PF13359.6 GBG74350.1 - 1.6e-16 60.4 0.0 1.7e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74350.1 - 3.2e-06 26.9 0.0 5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG74350.1 - 0.082 12.5 0.8 0.66 9.6 0.1 2.5 3 0 0 3 3 3 0 Transposase DDE domain Ion_trans PF00520.31 GBG74351.1 - 2.9e-40 138.0 16.7 3.8e-40 137.7 16.7 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 GBG74351.1 - 2.4e-07 29.8 11.7 9.2e-07 27.9 6.1 2.1 1 1 1 2 2 2 2 Polycystin cation channel TrkH PF02386.16 GBG74351.1 - 0.001 17.6 3.9 0.0017 16.9 3.9 1.2 1 0 0 1 1 1 1 Cation transport protein Retrotrans_gag PF03732.17 GBG74352.1 - 3.8e-05 23.9 3.4 0.00017 21.8 0.1 3.5 4 0 0 4 4 4 1 Retrotransposon gag protein FAM76 PF16046.5 GBG74352.1 - 0.035 13.5 8.3 0.063 12.6 8.3 1.4 1 0 0 1 1 1 0 FAM76 protein DUF4666 PF15697.5 GBG74352.1 - 2 9.1 5.6 0.99 10.1 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) RT_RNaseH_2 PF17919.1 GBG74354.1 - 3.3e-13 49.5 0.0 1.1e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74354.1 - 1.1e-12 48.2 0.0 2.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG74354.1 - 3.5e-12 46.2 0.3 8.9e-12 44.9 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG74354.1 - 2.1e-11 44.1 0.0 1.7e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74354.1 - 2e-07 30.8 0.0 4.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG74354.1 - 2.4e-06 28.0 0.1 7.7e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74354.1 - 0.00039 21.0 0.0 0.001 19.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG74354.1 - 0.0059 16.9 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74354.1 - 0.12 12.2 0.8 0.28 11.0 0.8 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG74354.1 - 0.15 12.3 0.4 0.39 11.0 0.4 1.8 1 0 0 1 1 1 0 H2C2 zinc finger TEX19 PF15553.6 GBG74355.1 - 0.065 13.2 0.3 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF3959 PF13105.6 GBG74355.1 - 0.37 10.3 0.6 0.5 9.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Pro_isomerase PF00160.21 GBG74356.1 - 1.4e-26 93.6 0.6 1.6e-26 93.5 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRS1 PF04939.12 GBG74357.1 - 3.3e-51 173.3 2.4 3.3e-51 173.3 2.4 1.9 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) AAA_lid_2 PF17863.1 GBG74358.1 - 3.3e-18 65.3 0.0 1.4e-17 63.3 0.0 2.2 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 GBG74358.1 - 2.8e-15 56.3 0.2 4.9e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI VWA_2 PF13519.6 GBG74358.1 - 2.1e-12 47.7 0.0 5e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GBG74358.1 - 5.8e-08 33.2 0.0 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain MCM PF00493.23 GBG74358.1 - 6e-07 28.8 0.0 3.7e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 GBG74358.1 - 9.4e-06 25.4 0.1 0.025 14.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 GBG74358.1 - 0.00021 21.3 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GBG74358.1 - 0.0022 18.3 0.0 0.012 15.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain VIR_N PF15912.5 GBG74358.1 - 0.0099 15.5 2.6 0.018 14.7 2.6 1.4 1 0 0 1 1 1 1 Virilizer, N-terminal CCDC53 PF10152.9 GBG74358.1 - 0.01 16.3 1.9 0.01 16.3 1.9 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex VWA_3 PF13768.6 GBG74358.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain PAXIP1_C PF15364.6 GBG74358.1 - 0.046 14.0 9.4 0.1 12.9 9.4 1.5 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein AAA PF00004.29 GBG74358.1 - 0.058 13.8 0.0 0.37 11.2 0.0 2.5 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_8 PF17868.1 GBG74358.1 - 0.088 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA lid domain CDC45 PF02724.14 GBG74358.1 - 0.13 10.6 2.2 0.2 9.9 2.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CAP_N PF01213.19 GBG74358.1 - 0.13 11.7 5.9 0.23 10.9 5.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF444 PF04285.12 GBG74358.1 - 0.18 10.8 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF444) FAM176 PF14851.6 GBG74358.1 - 0.25 11.0 3.5 0.69 9.6 3.5 1.7 1 0 0 1 1 1 0 FAM176 family AAA_28 PF13521.6 GBG74358.1 - 0.25 11.6 0.1 0.25 11.6 0.1 2.1 2 0 0 2 2 1 0 AAA domain RXT2_N PF08595.11 GBG74358.1 - 0.44 10.6 4.2 1.1 9.3 4.2 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal WPP PF13943.6 GBG74358.1 - 0.65 10.4 3.2 5.3 7.5 0.7 2.6 2 0 0 2 2 2 0 WPP domain TFB6 PF17110.5 GBG74358.1 - 0.8 9.4 2.4 1.7 8.4 2.4 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Pox_Ag35 PF03286.14 GBG74358.1 - 0.85 9.4 6.6 1.8 8.3 6.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein AAA_16 PF13191.6 GBG74358.1 - 2.1 8.7 7.8 0.42 11.0 0.8 3.1 2 2 0 2 2 1 0 AAA ATPase domain SRP-alpha_N PF04086.13 GBG74359.1 - 0.8 9.6 15.5 0.022 14.7 8.0 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Suf PF05843.14 GBG74359.1 - 9.5 6.1 7.7 1.8 8.4 3.4 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RVT_1 PF00078.27 GBG74360.1 - 2.6e-12 46.7 0.0 5.4e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74360.1 - 2.4e-06 27.5 0.0 6e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74360.1 - 0.0011 19.2 0.0 0.0036 17.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TIP120 PF08623.10 GBG74361.1 - 4.8e-56 189.1 4.9 6.9e-55 185.4 0.3 3.7 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 GBG74361.1 - 5.2e-14 52.4 10.5 0.00081 19.7 0.1 6.9 4 3 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 GBG74361.1 - 6.5e-11 42.5 16.0 0.00048 20.6 0.1 10.5 9 3 3 12 12 11 3 HEAT-like repeat HEAT PF02985.22 GBG74361.1 - 4.3e-07 29.6 36.4 0.07 13.4 0.1 10.8 12 0 0 12 12 9 3 HEAT repeat Adaptin_N PF01602.20 GBG74361.1 - 1e-06 27.6 9.1 0.028 13.0 0.0 4.2 3 1 1 4 4 4 2 Adaptin N terminal region DUF3385 PF11865.8 GBG74361.1 - 3.5e-06 27.0 0.5 0.016 15.2 0.0 4.9 6 0 0 6 6 5 1 Domain of unknown function (DUF3385) UME PF08064.13 GBG74361.1 - 1e-05 25.4 1.1 2.4 8.1 0.1 5.7 5 2 1 6 6 5 1 UME (NUC010) domain IFRD PF05004.13 GBG74361.1 - 1.4e-05 24.4 18.0 0.078 12.1 1.2 4.9 5 0 0 5 5 5 3 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 GBG74361.1 - 0.00042 20.4 12.8 0.094 12.8 0.0 6.5 6 2 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GBG74361.1 - 0.0019 18.2 8.7 0.068 13.2 0.0 6.0 5 2 1 6 6 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 GBG74361.1 - 0.0026 17.9 2.8 3.6 7.8 0.0 5.3 5 2 1 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Gcn1_N PF12074.8 GBG74361.1 - 0.0027 17.1 1.2 1.3 8.3 0.0 3.5 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal API5 PF05918.11 GBG74361.1 - 0.0055 15.6 1.6 0.026 13.3 0.1 2.7 3 0 0 3 3 3 1 Apoptosis inhibitory protein 5 (API5) Vac14_Fab1_bd PF12755.7 GBG74361.1 - 0.035 14.7 0.0 5.5 7.7 0.0 3.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region U3snoRNP10 PF12397.8 GBG74361.1 - 0.039 14.3 1.6 1.5 9.2 0.0 4.0 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 10 DUF2397 PF09660.10 GBG74361.1 - 0.041 12.8 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Cnd3 PF12719.7 GBG74361.1 - 0.045 12.9 8.9 0.68 9.1 0.1 4.6 5 1 1 6 6 6 0 Nuclear condensing complex subunits, C-term domain LuxT_C PF18285.1 GBG74361.1 - 0.06 13.9 0.1 1.6 9.4 0.0 3.5 3 1 0 3 3 2 0 Tetracycline repressor LuxT C-terminal domain DUF1981 PF09324.10 GBG74361.1 - 0.13 12.1 0.2 15 5.5 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1981) rve PF00665.26 GBG74362.1 - 1.3e-16 60.9 0.1 2.8e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG74362.1 - 0.0032 17.2 0.0 0.0095 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Integrase_H2C2 PF17921.1 GBG74362.1 - 0.02 15.0 0.6 0.039 14.1 0.6 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain Chromo PF00385.24 GBG74362.1 - 0.038 13.9 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Pan3_PK PF18101.1 GBG74363.1 - 9.2e-54 181.2 0.1 9.2e-54 181.2 0.1 2.2 3 0 0 3 3 3 1 Pan3 Pseudokinase domain zf-CCCH PF00642.24 GBG74363.1 - 1.9e-07 30.8 4.0 7e-05 22.6 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG74363.1 - 0.0041 17.1 3.8 0.0088 16.1 3.8 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 GBG74363.1 - 0.011 15.5 0.8 0.011 15.5 0.8 1.8 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GBG74363.1 - 0.31 11.6 1.3 0.65 10.6 1.3 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCHC PF00098.23 GBG74364.1 - 1.1e-15 56.9 29.6 0.0011 19.0 0.1 5.3 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 GBG74364.1 - 2.5e-05 24.0 26.2 0.074 12.9 0.1 5.2 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 GBG74364.1 - 2.7e-05 23.8 26.3 0.31 10.8 0.4 5.5 5 0 0 5 5 5 5 Zinc knuckle WD40_alt PF14077.6 GBG74365.1 - 0.044 13.7 0.8 0.63 9.9 0.1 3.0 2 1 0 2 2 2 0 Alternative WD40 repeat motif PHTB1_C PF14728.6 GBG74365.1 - 0.085 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 PTHB1 C-terminus zf-CCHC PF00098.23 GBG74367.1 - 0.48 10.6 1.9 0.78 9.9 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG74369.1 - 6.1e-26 90.4 0.1 1e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74369.1 - 3.3e-23 82.0 0.2 5.6e-23 81.2 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74369.1 - 3.3e-20 72.6 0.0 5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAUS6_N PF14661.6 GBG74370.1 - 0.066 12.8 1.5 0.095 12.3 1.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Peptidase_S64 PF08192.11 GBG74370.1 - 0.27 9.7 0.4 0.36 9.3 0.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 PHD20L1_u1 PF16660.5 GBG74370.1 - 0.35 11.6 5.3 1.3 9.8 0.4 2.4 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 DUF3729 PF12526.8 GBG74370.1 - 0.64 11.6 6.9 2.1 10.0 6.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) Baculo_PEP_C PF04513.12 GBG74370.1 - 0.71 9.9 2.1 1.5 8.9 2.1 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RVT_1 PF00078.27 GBG74372.1 - 1.3e-24 87.0 0.1 2.2e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74372.1 - 5.6e-23 80.9 0.0 1.3e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74372.1 - 1.2e-18 67.3 0.0 2.7e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DAPDH_C PF16654.5 GBG74372.1 - 0.029 14.2 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain zf-CCHC PF00098.23 GBG74372.1 - 0.33 11.1 4.0 0.65 10.2 4.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Terminase_2 PF03592.16 GBG74374.1 - 0.032 14.7 0.6 0.086 13.3 0.6 1.6 1 0 0 1 1 1 0 Terminase small subunit Sigma70_ner PF04546.13 GBG74374.1 - 8.6 6.2 0.0 8.6 6.2 0.0 7.8 4 2 0 5 5 5 0 Sigma-70, non-essential region RT_RNaseH_2 PF17919.1 GBG74376.1 - 6.8e-31 106.3 0.0 1.3e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74376.1 - 1.2e-26 93.7 0.0 2.2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74376.1 - 1.3e-25 89.6 0.1 2.9e-25 88.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74376.1 - 1.9e-19 69.5 0.1 5.1e-19 68.1 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74376.1 - 2.8e-14 53.3 0.2 1e-13 51.5 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG74376.1 - 0.0015 18.7 0.0 0.0063 16.7 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG74378.1 - 2.3e-16 59.6 0.1 8.5e-16 57.8 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG74378.1 - 2.4e-08 34.2 0.0 5.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG74378.1 - 0.00028 21.4 0.0 0.0008 19.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG74378.1 - 0.0072 16.5 0.1 0.018 15.3 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG74378.1 - 0.018 15.7 0.0 0.047 14.3 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease USP8_interact PF08941.10 GBG74379.1 - 0.12 12.2 1.1 0.82 9.5 0.0 2.3 2 0 0 2 2 2 0 USP8 interacting DUF3089 PF11288.8 GBG74381.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) RF-1 PF00472.20 GBG74383.1 - 0.0028 17.6 0.7 0.0047 16.9 0.3 1.6 2 0 0 2 2 2 1 RF-1 domain DDE_Tnp_4 PF13359.6 GBG74385.1 - 5e-26 91.3 0.0 1.2e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74385.1 - 2.6e-08 33.7 0.0 5.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein RT_RNaseH PF17917.1 GBG74387.1 - 4.8e-22 78.2 0.4 1.3e-21 76.8 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74387.1 - 1.1e-13 51.1 0.0 2.7e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Es2 PF09751.9 GBG74387.1 - 0.11 12.3 18.4 0.17 11.6 18.4 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 Phage_GPO PF05929.11 GBG74387.1 - 0.34 10.5 0.0 0.34 10.5 0.0 3.1 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH PF17917.1 GBG74390.1 - 2e-29 101.9 0.0 5.5e-29 100.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74390.1 - 7.7e-21 74.0 0.0 2.6e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74390.1 - 7.3e-17 61.2 1.2 1.6e-16 60.2 1.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG74390.1 - 7.7e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74390.1 - 0.0021 18.7 0.0 0.005 17.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG74390.1 - 0.03 14.5 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 GBG74390.1 - 0.048 13.9 0.1 0.15 12.3 0.1 1.9 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG74390.1 - 0.088 13.4 0.0 0.4 11.3 0.0 2.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG74390.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 GBG74391.1 - 3.9e-33 113.3 1.7 5.5e-16 58.4 0.1 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG74391.1 - 8.4e-32 109.2 0.0 2e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74391.1 - 8.7e-29 99.9 1.4 1.8e-28 98.9 0.4 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74391.1 - 1.1e-13 51.4 0.1 3.2e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG74391.1 - 2e-10 40.6 0.1 4.6e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG74391.1 - 2.8e-07 30.7 0.9 0.0059 16.9 0.2 4.4 3 0 0 3 3 3 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG74391.1 - 4.2e-05 23.7 0.0 0.38 11.0 0.0 2.9 2 0 0 2 2 2 2 H2C2 zinc finger DUF2862 PF11061.8 GBG74391.1 - 0.001 18.8 1.1 0.55 10.1 0.1 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2862) DUF1564 PF07600.11 GBG74391.1 - 0.029 14.1 0.2 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DUF4407 PF14362.6 GBG74391.1 - 1.6 8.0 18.8 0.089 12.1 12.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG74392.1 - 3.1e-39 134.8 0.1 7.8e-25 87.7 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74392.1 - 3.4e-14 52.7 0.3 9e-14 51.3 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Laminin_G_3 PF13385.6 GBG74392.1 - 1.3e-07 31.9 0.0 0.0012 19.0 0.0 2.8 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily RVP_2 PF08284.11 GBG74392.1 - 7.3e-05 22.5 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74392.1 - 7.8e-05 23.2 0.0 0.00028 21.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG74392.1 - 0.024 14.4 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG74392.1 - 0.045 14.3 0.0 0.17 12.5 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Laminin_G_2 PF02210.24 GBG74392.1 - 0.14 12.7 0.0 0.41 11.2 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain RVT_1 PF00078.27 GBG74393.1 - 6.6e-15 55.2 0.1 9.4e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74394.1 - 2.3e-18 66.4 0.0 4.8e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74394.1 - 2.4e-10 40.3 0.0 5.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG74394.1 - 1.9e-07 30.8 1.3 4.4e-07 29.7 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG74394.1 - 0.00021 21.0 2.1 0.00048 19.9 2.1 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG74394.1 - 0.0057 17.2 0.0 0.02 15.4 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74394.1 - 0.013 16.1 0.0 0.046 14.4 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease Arm PF00514.23 GBG74395.1 - 0.042 13.9 1.5 0.39 10.8 0.1 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF2517 PF10725.9 GBG74395.1 - 0.15 11.9 0.3 0.39 10.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) HEAT_2 PF13646.6 GBG74395.1 - 0.23 11.9 2.7 34 4.9 0.0 4.0 4 1 0 4 4 4 0 HEAT repeats HEAT PF02985.22 GBG74395.1 - 0.82 10.1 2.8 4.3 7.9 0.1 3.4 4 0 0 4 4 4 0 HEAT repeat XRN1_D1 PF18332.1 GBG74396.1 - 2.1 8.1 7.9 0.51 10.1 3.2 2.4 2 1 0 2 2 2 0 Exoribonuclease Xrn1 D1 domain Myb_DNA-bind_4 PF13837.6 GBG74397.1 - 8.5e-08 32.5 2.9 1.6e-07 31.6 0.5 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG74397.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVT_1 PF00078.27 GBG74399.1 - 8.4e-33 113.7 0.1 1.5e-32 112.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74399.1 - 1.2e-28 99.4 0.0 5.5e-28 97.3 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74399.1 - 3e-28 97.8 0.0 2.1e-27 95.0 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74399.1 - 1e-18 67.2 0.5 2.5e-18 65.9 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG74399.1 - 2.8e-05 24.2 0.1 0.00012 22.2 0.1 2.1 1 0 0 1 1 1 1 H2C2 zinc finger DUF1933 PF09147.10 GBG74399.1 - 0.16 11.5 0.0 0.48 10.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1933) DUF3138 PF11336.8 GBG74399.1 - 0.21 10.1 1.4 0.33 9.5 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RVT_1 PF00078.27 GBG74400.1 - 1.4e-05 24.8 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_4 PF14392.6 GBG74400.1 - 0.064 13.0 1.7 0.13 12.0 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG74400.1 - 0.62 10.2 3.2 1.1 9.4 1.6 2.3 2 0 0 2 2 2 0 Zinc knuckle CENP-N PF05238.13 GBG74400.1 - 6.2 6.0 6.7 3.2 7.0 3.4 2.1 2 0 0 2 2 2 0 Kinetochore protein CHL4 like zf-CCHC PF00098.23 GBG74401.1 - 0.00064 19.7 2.3 0.00064 19.7 2.3 2.2 2 0 0 2 2 2 1 Zinc knuckle HAUS-augmin3 PF14932.6 GBG74401.1 - 2.2 7.8 7.6 1.4 8.5 5.5 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 zf-CCHC_2 PF13696.6 GBG74401.1 - 3.5 7.5 5.1 1.6 8.7 2.1 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF4407 PF14362.6 GBG74402.1 - 0.53 9.6 12.5 0.025 13.9 2.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YjbH PF06082.11 GBG74402.1 - 4.2 6.1 8.9 0.4 9.4 4.7 1.3 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH RVT_1 PF00078.27 GBG74403.1 - 2.4e-33 115.5 0.1 4.6e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74403.1 - 3.2e-31 107.3 0.0 1.2e-30 105.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74403.1 - 1e-30 106.1 0.0 2.2e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74403.1 - 1.6e-19 69.7 0.4 3.6e-19 68.6 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74403.1 - 6e-17 61.9 0.0 1.4e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74403.1 - 0.00025 21.2 0.1 0.00072 19.7 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG74403.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Ssu72 PF04722.13 GBG74403.1 - 0.12 11.9 0.2 0.99 8.9 0.0 2.4 2 1 1 3 3 3 0 Ssu72-like protein DUF4392 PF14336.6 GBG74403.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) CCD48 PF15799.5 GBG74404.1 - 0.015 13.6 1.3 0.027 12.8 1.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF2385 PF09539.10 GBG74404.1 - 0.079 13.5 0.7 1.8 9.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) HALZ PF02183.18 GBG74404.1 - 0.1 12.8 1.5 0.3 11.4 1.5 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 GBG74404.1 - 0.69 10.0 5.0 0.44 10.7 1.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper RVT_1 PF00078.27 GBG74406.1 - 2.4e-24 86.1 0.1 4.4e-24 85.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG74406.1 - 0.00084 19.1 0.0 0.032 13.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Chromo PF00385.24 GBG74406.1 - 0.026 14.4 0.0 0.075 13.0 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG74406.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF5095 PF17016.5 GBG74406.1 - 0.12 12.1 0.2 0.24 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) RVT_1 PF00078.27 GBG74407.1 - 2.8e-27 95.7 0.1 6.2e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74407.1 - 9.5e-16 57.7 0.4 2e-15 56.6 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74407.1 - 3.1e-14 53.2 0.0 1.1e-13 51.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG74407.1 - 0.026 14.5 0.1 0.081 13.0 0.1 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG74407.1 - 0.034 14.4 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG74407.1 - 0.068 13.4 0.1 0.31 11.4 0.1 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG74408.1 - 1.3e-14 54.0 1.5 2.1e-14 53.3 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG74408.1 - 1.5e-09 38.0 0.0 4.9e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74408.1 - 7.8e-05 22.8 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Dimer_Tnp_hAT PF05699.14 GBG74409.1 - 1.5e-07 31.1 0.0 3.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG74409.1 - 5.9e-05 23.0 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4715 PF15835.5 GBG74410.1 - 2.1 8.4 11.8 17 5.5 8.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) Membralin PF09746.9 GBG74410.1 - 5.1 6.0 5.6 9 5.2 5.6 1.4 1 0 0 1 1 1 0 Tumour-associated protein rve PF00665.26 GBG74411.1 - 9.5e-33 112.9 0.0 6.8e-11 42.4 0.0 3.7 3 0 0 3 3 3 3 Integrase core domain Integrase_H2C2 PF17921.1 GBG74411.1 - 2.9e-18 65.7 0.0 6e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG74411.1 - 2.4e-11 44.1 0.0 2.9e-07 31.0 0.0 3.0 3 0 0 3 3 2 2 Aspartyl protease Retrotrans_gag PF03732.17 GBG74411.1 - 1.1e-10 41.6 6.3 0.0082 16.4 0.0 4.4 4 0 0 4 4 4 3 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG74411.1 - 1.5e-10 41.0 0.0 5.9e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG74411.1 - 1.1e-09 38.7 0.0 1.3e-05 25.7 0.0 3.1 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74411.1 - 1.9e-07 30.9 0.0 1.2e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74411.1 - 1e-05 25.3 0.0 0.02 14.7 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease rve_3 PF13683.6 GBG74411.1 - 0.0015 18.2 0.0 0.027 14.3 0.0 2.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG74411.1 - 0.018 15.3 0.0 0.06 13.6 0.0 1.9 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG74411.1 - 0.1 12.8 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG74412.1 - 6.9e-22 77.4 0.0 1.7e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74412.1 - 6.9e-12 45.4 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74412.1 - 3e-11 43.5 0.0 9e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4746 PF15928.5 GBG74412.1 - 0.53 9.7 8.2 0.87 8.9 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RT_RNaseH_2 PF17919.1 GBG74413.1 - 1.5e-32 111.6 0.0 3.9e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74413.1 - 6.9e-22 77.7 0.0 2.2e-21 76.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74413.1 - 5.7e-16 58.8 0.1 3e-15 56.4 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain FAM199X PF15814.5 GBG74413.1 - 1.4 7.9 9.5 2.4 7.2 9.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X RVT_1 PF00078.27 GBG74414.1 - 5.3e-33 114.4 0.1 1e-32 113.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74414.1 - 4.6e-29 100.4 0.0 9.2e-29 99.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74414.1 - 1.3e-24 86.5 0.0 2.4e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74414.1 - 1.7e-16 60.5 0.0 4.4e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG74414.1 - 8e-16 57.9 0.1 2e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG74414.1 - 0.00022 21.4 0.0 0.00073 19.7 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Es2 PF09751.9 GBG74415.1 - 0.0077 16.0 17.0 0.011 15.5 17.0 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 Presenilin PF01080.17 GBG74415.1 - 0.51 9.1 16.8 5.7 5.6 16.8 2.0 1 1 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG74416.1 - 1.3e-31 108.5 0.1 4.3e-31 106.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74416.1 - 4.2e-30 104.1 0.7 1.2e-29 102.7 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG74416.1 - 0.026 14.1 0.0 0.026 14.1 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG74417.1 - 9.6e-47 159.3 0.6 6.3e-27 94.5 0.2 3.2 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74417.1 - 1.7e-46 156.4 0.0 3e-26 91.4 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74417.1 - 9.2e-37 125.5 0.0 9.9e-24 83.6 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG74417.1 - 8.1e-06 25.7 2.6 2.6e-05 24.1 2.6 1.9 1 0 0 1 1 1 1 Zinc knuckle SAP PF02037.27 GBG74417.1 - 0.0022 17.7 0.1 0.0076 16.0 0.1 2.1 1 0 0 1 1 1 1 SAP domain Rhamno_transf PF11316.8 GBG74417.1 - 0.052 12.9 0.1 0.53 9.6 0.0 2.5 2 0 0 2 2 2 0 Putative rhamnosyl transferase Sec34 PF04136.15 GBG74417.1 - 0.052 13.4 0.6 0.18 11.7 0.6 1.9 1 0 0 1 1 1 0 Sec34-like family Baculo_PEP_C PF04513.12 GBG74417.1 - 0.7 9.9 6.4 1.7 8.7 6.4 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus gag-asp_proteas PF13975.6 GBG74418.1 - 6.4e-06 26.6 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74418.1 - 5e-05 23.9 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74418.1 - 0.00012 22.2 2.4 0.19 12.0 0.3 2.8 2 0 0 2 2 2 2 Retrotransposon gag protein DUF1758 PF05585.12 GBG74418.1 - 0.037 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG74418.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74418.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RLL PF10036.9 GBG74418.1 - 0.13 12.0 4.1 0.26 11.1 0.1 2.6 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein Docking PF08990.11 GBG74418.1 - 0.42 10.3 2.1 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 Erythronolide synthase docking RVT_1 PF00078.27 GBG74419.1 - 5.4e-25 88.2 0.2 1.2e-24 87.1 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74419.1 - 3.7e-23 81.4 0.0 1e-22 80.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74419.1 - 7.4e-22 77.6 0.0 1.3e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase tRNA-synt_1_2 PF13603.6 GBG74420.1 - 0.064 12.8 0.4 0.064 12.8 0.4 1.9 1 1 1 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 WAP PF00095.21 GBG74420.1 - 0.12 12.8 3.3 10 6.6 0.2 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF4607 PF15380.6 GBG74420.1 - 0.12 11.8 5.7 0.18 11.3 5.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4607) DUF3323 PF11796.8 GBG74420.1 - 0.43 10.4 10.2 0.59 10.0 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Presenilin PF01080.17 GBG74420.1 - 0.79 8.4 7.2 0.94 8.2 7.2 1.1 1 0 0 1 1 1 0 Presenilin YABBY PF04690.13 GBG74420.1 - 5 7.7 7.2 0.96 10.0 3.4 1.7 2 1 0 2 2 2 0 YABBY protein RT_RNaseH_2 PF17919.1 GBG74421.1 - 5.7e-25 87.3 0.0 1.2e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74421.1 - 2.3e-22 79.3 0.0 2.7e-21 75.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74421.1 - 0.0045 16.5 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HIP1_clath_bdg PF16515.5 GBG74421.1 - 0.12 13.0 2.9 0.17 12.5 0.8 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RVT_1 PF00078.27 GBG74423.1 - 7.7e-28 97.5 0.1 1.2e-27 96.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ZapB PF06005.12 GBG74423.1 - 1.4 9.4 10.5 1.6 9.2 0.1 3.0 2 1 0 2 2 2 0 Cell division protein ZapB Histone_HNS PF00816.21 GBG74423.1 - 2 9.3 7.6 1.2 10.0 5.1 1.9 2 0 0 2 2 2 0 H-NS histone family Chromo PF00385.24 GBG74424.1 - 1.3e-10 41.0 0.0 2.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4537 PF15057.6 GBG74424.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Mtf2_C PF14061.6 GBG74424.1 - 0.16 12.1 0.0 0.77 10.0 0.0 2.2 2 1 0 2 2 2 0 Polycomb-like MTF2 factor 2 rve PF00665.26 GBG74425.1 - 8.3e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG74425.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG74426.1 - 9.4e-17 61.3 0.0 1.8e-16 60.3 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74426.1 - 5.7e-10 39.1 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Hep_59 PF07052.11 GBG74426.1 - 0.089 13.5 7.0 0.18 12.6 7.0 1.4 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 CRA PF06589.11 GBG74426.1 - 0.66 10.1 5.8 1.5 9.0 5.8 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF1943 PF09172.11 GBG74426.1 - 2.1 7.5 5.3 3.1 6.9 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Cid2 PF09774.9 GBG74426.1 - 5.5 7.4 10.4 0.97 9.8 0.1 2.4 2 0 0 2 2 2 0 Caffeine-induced death protein 2 RVT_1 PF00078.27 GBG74428.1 - 5e-31 108.0 0.1 1e-30 106.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74428.1 - 1e-29 102.5 0.0 4.4e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74428.1 - 1.3e-29 102.5 0.3 5.2e-29 100.6 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74428.1 - 1.1e-19 70.2 0.8 3.5e-19 68.6 0.8 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74428.1 - 7.2e-17 61.7 0.0 1.8e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74428.1 - 0.00023 21.3 0.0 0.00068 19.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG74428.1 - 0.051 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Latarcin PF10279.9 GBG74428.1 - 0.24 11.9 0.5 1 9.8 0.1 2.2 2 0 0 2 2 2 0 Latarcin precursor PmbA_TldD PF01523.16 GBG74429.1 - 0.062 13.1 5.1 0.076 12.8 5.1 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase RE_AlwI PF09491.10 GBG74429.1 - 0.81 8.4 9.0 0.36 9.6 6.8 1.5 1 1 1 2 2 2 0 AlwI restriction endonuclease Med9 PF07544.13 GBG74429.1 - 0.88 9.7 12.5 0.76 9.9 4.1 2.9 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 USP8_interact PF08941.10 GBG74429.1 - 1 9.2 6.0 0.1 12.4 1.9 1.5 2 0 0 2 2 2 0 USP8 interacting TP53IP5 PF15331.6 GBG74429.1 - 1.9 8.6 10.1 2 8.5 10.1 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF16 PF01519.16 GBG74429.1 - 5.3 7.6 10.9 3.1 8.3 8.4 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4407 PF14362.6 GBG74429.1 - 6 6.1 13.8 6.7 6.0 13.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PA26 PF04636.13 GBG74429.1 - 7.6 5.3 8.7 8.2 5.2 8.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF659 PF04937.15 GBG74430.1 - 6.3e-17 61.8 0.0 1.6e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG74430.1 - 8.8e-05 22.7 0.0 0.72 10.2 0.0 2.7 2 0 0 2 2 2 2 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG74431.1 - 1.3e-16 60.4 0.4 4.1e-16 58.8 0.4 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74431.1 - 9.9e-09 35.4 0.1 3.4e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG74431.1 - 6.3e-07 29.6 0.2 1.4e-06 28.5 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG74431.1 - 0.063 13.5 0.1 0.17 12.1 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG74432.1 - 1.1e-29 103.5 0.0 2e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74432.1 - 5.4e-17 62.0 2.2 3.6e-16 59.4 1.5 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74432.1 - 1.5e-09 38.1 0.0 4.4e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG74432.1 - 1.3e-08 34.7 0.3 9.8e-08 32.0 0.1 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74432.1 - 1.4e-06 28.9 0.0 3.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74432.1 - 3.7e-06 27.4 0.0 9.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74432.1 - 0.00021 21.1 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74432.1 - 0.00028 20.7 0.0 0.00093 19.0 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Laminin_G_3 PF13385.6 GBG74433.1 - 4.8e-28 98.2 7.4 1.2e-12 48.2 0.0 6.6 5 2 0 5 5 5 3 Concanavalin A-like lectin/glucanases superfamily Filamin PF00630.19 GBG74433.1 - 0.0056 17.5 0.0 3.9 8.3 0.0 3.6 3 0 0 3 3 3 1 Filamin/ABP280 repeat Laminin_G_2 PF02210.24 GBG74433.1 - 0.065 13.8 0.0 35 5.0 0.0 3.1 3 0 0 3 3 3 0 Laminin G domain Patatin PF01734.22 GBG74434.1 - 0.042 14.0 0.1 0.092 12.9 0.1 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase RT_RNaseH_2 PF17919.1 GBG74436.1 - 2.4e-25 88.5 0.0 5.4e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74436.1 - 4.4e-24 84.8 0.0 9.1e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74436.1 - 2.7e-23 82.7 0.1 4.6e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74436.1 - 3.5e-17 62.3 0.3 8.8e-17 61.0 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG74436.1 - 1.6e-05 25.5 0.0 4.2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74436.1 - 3.1e-05 24.5 0.0 6.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG74436.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74436.1 - 0.00022 21.4 0.1 0.015 15.5 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG74436.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease BACK PF07707.15 GBG74437.1 - 0.061 13.4 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 BTB And C-terminal Kelch PDGF_N PF04692.13 GBG74437.1 - 0.097 13.5 0.1 0.17 12.7 0.1 1.4 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region RVT_1 PF00078.27 GBG74438.1 - 4.4e-29 101.6 0.0 1.5e-28 99.9 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74438.1 - 9e-26 89.8 0.0 7.7e-25 86.8 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74438.1 - 3.8e-24 85.0 0.0 1.3e-23 83.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74438.1 - 1e-07 32.5 0.0 4.5e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74438.1 - 5e-07 30.2 0.2 4.8e-06 27.0 0.0 2.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG74438.1 - 9.9e-07 28.8 0.1 2.3e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG74438.1 - 2.6e-06 27.2 0.0 5.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74438.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease GIT_CC PF16559.5 GBG74438.1 - 0.19 11.6 0.8 8.8 6.3 0.1 2.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 GBG74438.1 - 0.8 9.0 14.8 2.4 7.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DraK_HK_N PF18092.1 GBG74438.1 - 1 9.8 5.3 12 6.4 0.0 3.0 3 0 0 3 3 2 0 DraK Histidine Kinase N-terminal domain Retrotrans_gag PF03732.17 GBG74438.1 - 1.2 9.5 4.5 17 5.8 0.0 3.7 4 0 0 4 4 3 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG74439.1 - 1e-25 90.6 0.2 2.3e-25 89.4 0.2 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74439.1 - 2.5e-10 40.3 0.0 1.3e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74439.1 - 6.7e-07 29.9 0.0 1.7e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74439.1 - 2.9e-06 27.8 0.0 8.9e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74439.1 - 2.9e-05 23.9 0.0 6.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74439.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74439.1 - 0.0074 16.5 0.0 0.0074 16.5 0.0 5.1 5 1 0 5 5 5 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG74439.1 - 0.038 14.3 0.1 0.23 11.8 0.0 2.5 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase BTB PF00651.31 GBG74440.1 - 1.5e-33 115.3 0.1 4.4e-23 81.6 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Methyltransf_FA PF12248.8 GBG74440.1 - 1.3e-13 51.1 0.0 3.1e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase FoP_duplication PF13865.6 GBG74441.1 - 7.1e-13 48.9 13.6 7.1e-13 48.9 13.6 4.8 4 1 2 6 6 6 1 C-terminal duplication domain of Friend of PRMT1 Med15 PF09606.10 GBG74441.1 - 0.55 8.9 16.2 0.7 8.5 16.2 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1995 PF09353.10 GBG74443.1 - 1.7e-32 113.1 0.0 2.5e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) RVP_2 PF08284.11 GBG74444.1 - 8.6e-09 35.3 0.0 5e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74444.1 - 1.2e-08 35.4 0.0 4.3e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74444.1 - 1.3e-06 28.9 0.0 1.1e-05 25.9 0.0 2.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG74444.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74444.1 - 0.0084 16.4 0.0 0.032 14.5 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein Pan_kinase PF03309.14 GBG74444.1 - 0.062 13.1 0.2 0.23 11.3 0.2 1.9 2 0 0 2 2 2 0 Type III pantothenate kinase AMP-binding_C_2 PF14535.6 GBG74444.1 - 0.11 12.8 0.0 0.6 10.5 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain zf-CCHC_3 PF13917.6 GBG74445.1 - 0.0012 18.8 0.6 0.0026 17.7 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF3863 PF12979.7 GBG74445.1 - 0.045 12.6 0.0 0.09 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Retrotrans_gag PF03732.17 GBG74445.1 - 0.084 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Rad9 PF04139.13 GBG74445.1 - 0.11 11.9 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Rad9 DUF659 PF04937.15 GBG74447.1 - 2.2e-35 121.7 0.0 4e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG74447.1 - 3.3 7.9 9.4 0.33 11.0 2.6 2.8 2 0 0 2 2 2 0 AT hook motif DivIC PF04977.15 GBG74448.1 - 0.41 10.5 4.4 1.3 8.8 4.4 1.9 1 0 0 1 1 1 0 Septum formation initiator RT_RNaseH_2 PF17919.1 GBG74449.1 - 4.3e-32 110.1 0.0 6e-16 58.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74449.1 - 9e-31 107.1 0.0 1.6e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74449.1 - 1.1e-30 106.0 0.0 2.2e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 GBG74449.1 - 0.21 11.4 0.1 0.43 10.4 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like G8 PF10162.9 GBG74450.1 - 7e-60 200.5 0.0 9.2e-29 100.0 0.0 2.6 2 0 0 2 2 2 2 G8 domain RVT_1 PF00078.27 GBG74450.1 - 4.9e-39 134.1 0.0 1.3e-38 132.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TIG PF01833.24 GBG74450.1 - 1.6e-34 117.9 8.4 1.5e-09 37.8 0.3 6.5 5 1 0 5 5 5 5 IPT/TIG domain DUF659 PF04937.15 GBG74450.1 - 1.5e-18 67.1 0.0 3.8e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Beta_helix PF13229.6 GBG74450.1 - 5.4e-11 42.6 11.4 0.0015 18.4 1.2 4.4 3 1 1 4 4 4 4 Right handed beta helix region NosD PF05048.13 GBG74450.1 - 1.2e-05 24.7 8.5 0.006 15.9 0.1 3.3 2 1 2 4 4 4 2 Periplasmic copper-binding protein (NosD) DUF262 PF03235.14 GBG74450.1 - 9.7e-05 22.6 0.1 0.00032 21.0 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF262 Protocadherin PF08374.11 GBG74450.1 - 1.3 8.9 3.3 3 7.8 3.3 1.5 1 0 0 1 1 1 0 Protocadherin G8 PF10162.9 GBG74451.1 - 7.7e-60 200.4 0.0 9.6e-29 100.0 0.0 2.6 2 0 0 2 2 2 2 G8 domain RVT_1 PF00078.27 GBG74451.1 - 5.3e-39 134.0 0.0 1.4e-38 132.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TIG PF01833.24 GBG74451.1 - 2e-34 117.5 8.4 1.6e-09 37.7 0.3 6.5 5 1 0 5 5 5 5 IPT/TIG domain DUF659 PF04937.15 GBG74451.1 - 1.6e-18 67.0 0.0 4e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Beta_helix PF13229.6 GBG74451.1 - 1.6e-08 34.5 10.9 0.0014 18.5 1.1 4.5 3 1 1 4 4 4 3 Right handed beta helix region DUF262 PF03235.14 GBG74451.1 - 9.9e-05 22.6 0.1 0.00033 20.9 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF262 NosD PF05048.13 GBG74451.1 - 0.001 18.4 5.5 0.49 9.6 0.1 3.8 3 1 0 3 3 3 2 Periplasmic copper-binding protein (NosD) DUF1664 PF07889.12 GBG74451.1 - 0.32 11.0 3.6 0.92 9.6 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Protocadherin PF08374.11 GBG74451.1 - 1.4 8.9 3.3 3.1 7.7 3.3 1.5 1 0 0 1 1 1 0 Protocadherin TIG PF01833.24 GBG74452.1 - 2.4e-38 130.1 22.8 1.6e-08 34.5 0.1 6.6 6 0 0 6 6 6 6 IPT/TIG domain PA14 PF07691.12 GBG74452.1 - 2.7e-09 37.0 0.0 1e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 PA14 domain DUF5068 PF16781.5 GBG74452.1 - 0.0091 15.8 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5068) GLEYA PF10528.9 GBG74452.1 - 0.056 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 GLEYA domain RVP_2 PF08284.11 GBG74453.1 - 0.032 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Orf78 PF06024.12 GBG74453.1 - 2.3 8.5 4.9 4.2 7.7 4.9 1.3 1 0 0 1 1 1 0 Orf78 (ac78) RT_RNaseH PF17917.1 GBG74454.1 - 3.8e-27 94.6 0.9 2.1e-26 92.3 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74454.1 - 2.1e-26 91.8 0.0 7.5e-26 90.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ZapB PF06005.12 GBG74454.1 - 0.015 15.7 0.8 0.015 15.7 0.8 6.9 4 3 0 4 4 4 0 Cell division protein ZapB Antigen_C PF16364.5 GBG74454.1 - 6.2 7.2 9.0 2 8.8 2.7 2.7 3 0 0 3 3 3 0 Cell surface antigen C-terminus RT_RNaseH PF17917.1 GBG74455.1 - 4e-27 94.6 0.0 1e-26 93.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74455.1 - 1.8e-26 92.1 0.0 3.8e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DRY_EERY PF09750.9 GBG74455.1 - 2.2 8.6 0.0 2.2 8.6 0.0 3.0 2 1 1 3 3 3 0 Alternative splicing regulator DUF1658 PF07871.11 GBG74456.1 - 0.059 13.3 0.7 0.059 13.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) CRT10 PF08728.10 GBG74456.1 - 0.11 10.6 4.1 0.13 10.4 4.1 1.0 1 0 0 1 1 1 0 CRT10 FANCM-MHF_bd PF16783.5 GBG74456.1 - 0.5 10.4 7.3 0.079 13.0 2.2 2.1 1 1 1 2 2 2 0 FANCM to MHF binding domain CsgE PF10627.9 GBG74456.1 - 0.93 9.7 5.7 2.1 8.6 5.0 2.0 1 1 0 1 1 1 0 Curli assembly protein CsgE TMF_DNA_bd PF12329.8 GBG74456.1 - 1.1 9.3 12.0 0.54 10.3 0.2 3.0 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding RT_RNaseH_2 PF17919.1 GBG74457.1 - 7.9e-27 93.2 0.0 2e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74457.1 - 2.6e-26 92.5 0.1 4e-26 91.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74457.1 - 6.1e-24 84.3 0.0 1.5e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74457.1 - 7e-19 67.7 0.3 2.1e-18 66.2 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG74457.1 - 7.1e-07 29.8 0.0 1.7e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74457.1 - 1.4e-06 28.8 0.0 3.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74457.1 - 2.7e-06 27.2 0.0 5.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG74457.1 - 9.1e-05 22.6 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG74457.1 - 0.00029 20.6 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG74457.1 - 0.00092 19.1 0.3 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG74457.1 - 0.0046 17.1 0.1 0.014 15.6 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger GLEYA PF10528.9 GBG74458.1 - 0.0035 17.7 0.6 0.0089 16.4 0.6 1.7 1 0 0 1 1 1 1 GLEYA domain DUF4314 PF14192.6 GBG74458.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) RT_RNaseH_2 PF17919.1 GBG74459.1 - 5.9e-27 93.6 0.0 1.3e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RRM_1 PF00076.22 GBG74459.1 - 2.6e-24 84.8 0.2 2e-12 46.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RT_RNaseH PF17917.1 GBG74459.1 - 8.6e-21 74.2 0.0 2.1e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74459.1 - 1.5e-10 41.0 0.1 3.3e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nup35_RRM_2 PF14605.6 GBG74459.1 - 4.7e-05 23.3 0.1 0.0032 17.4 0.0 2.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 GBG74459.1 - 0.0012 18.8 0.0 0.36 10.9 0.0 2.8 2 0 0 2 2 2 1 RNA binding domain Retrotrans_gag PF03732.17 GBG74459.1 - 0.0087 16.3 0.1 0.076 13.3 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein RRM_5 PF13893.6 GBG74459.1 - 0.0097 15.5 0.0 0.3 10.7 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Integrase_H2C2 PF17921.1 GBG74461.1 - 1.9e-39 133.6 2.8 6.9e-19 67.7 0.2 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG74461.1 - 2.3e-25 88.9 0.0 1.9e-21 76.3 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74461.1 - 5.1e-25 87.4 0.0 1.3e-24 86.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74461.1 - 3e-19 69.4 0.0 6.8e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG74461.1 - 1.6e-09 38.0 0.0 5.3e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74461.1 - 2e-05 24.7 0.0 0.072 13.3 0.0 2.7 2 0 0 2 2 2 2 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG74461.1 - 0.0022 18.2 5.9 0.012 15.9 0.1 3.7 3 0 0 3 3 3 1 Retrotransposon gag protein SPACA9 PF15120.6 GBG74461.1 - 0.24 11.2 1.4 0.67 9.7 1.4 1.7 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Cytochrom_c3_2 PF14537.6 GBG74461.1 - 0.36 11.3 6.4 1.4 9.4 6.4 2.0 1 0 0 1 1 1 0 Cytochrome c3 LMBR1 PF04791.16 GBG74461.1 - 2.3 7.1 4.1 4.1 6.2 4.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein HIP1_clath_bdg PF16515.5 GBG74461.1 - 2.8 8.6 16.3 0.02 15.5 2.8 2.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DNA_pol_phi PF04931.13 GBG74462.1 - 4.8 5.2 16.7 5.6 4.9 16.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi EF-hand_7 PF13499.6 GBG74463.1 - 0.00053 20.4 0.2 0.0014 19.0 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GBG74463.1 - 0.0026 17.6 0.1 0.0053 16.6 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG74463.1 - 0.039 13.9 0.1 0.42 10.7 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain DUF4698 PF15769.5 GBG74463.1 - 0.12 11.4 2.8 0.17 10.9 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) PSI_PsaH PF03244.14 GBG74464.1 - 0.16 11.4 6.4 0.24 10.9 1.5 2.0 1 1 1 2 2 2 0 Photosystem I reaction centre subunit VI AA_permease PF00324.21 GBG74464.1 - 0.3 9.6 2.0 0.42 9.2 2.0 1.2 1 0 0 1 1 1 0 Amino acid permease PsbW PF07123.12 GBG74464.1 - 1 9.4 9.3 1 9.3 8.7 1.4 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Glutaredoxin PF00462.24 GBG74465.1 - 4.3e-16 58.9 0.0 6.5e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 GBG74465.1 - 3.5e-05 23.8 0.0 5.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 GBG74465.1 - 0.00033 21.1 0.1 0.00095 19.6 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 GBG74465.1 - 0.00098 19.5 0.0 0.0017 18.7 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 GBG74465.1 - 0.0038 17.4 0.1 0.71 10.0 0.2 2.2 1 1 1 2 2 2 2 Thioredoxin DSBA PF01323.20 GBG74465.1 - 0.0057 16.4 1.3 0.057 13.2 0.1 2.3 2 1 1 3 3 3 1 DSBA-like thioredoxin domain Thioredoxin PF00085.20 GBG74465.1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin GST_N_2 PF13409.6 GBG74465.1 - 0.092 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_7 PF13899.6 GBG74465.1 - 0.12 12.5 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 GBG74465.1 - 0.18 11.6 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF3138 PF11336.8 GBG74467.1 - 2.4 6.7 3.9 4.8 5.7 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ACBP PF00887.19 GBG74468.1 - 2.6e-27 94.8 1.3 2.9e-27 94.7 1.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Mon2_C PF16206.5 GBG74470.1 - 1.6e-56 192.0 0.0 1.4e-46 159.1 0.0 3.9 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DCB PF16213.5 GBG74470.1 - 2.8e-43 147.7 1.8 8.4e-43 146.1 1.8 1.8 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 GBG74470.1 - 8.4e-34 116.8 2.0 1.3e-32 112.9 0.2 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GBG74470.1 - 3.4e-05 23.6 0.0 0.0014 18.4 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) HEAT PF02985.22 GBG74470.1 - 0.00012 22.0 1.8 1.8 9.0 0.0 4.5 3 0 0 3 3 3 2 HEAT repeat He_PIG PF05345.12 GBG74470.1 - 0.037 14.2 0.1 0.091 13.0 0.1 1.7 1 0 0 1 1 1 0 Putative Ig domain RVT_1 PF00078.27 GBG74471.1 - 2.9e-26 92.4 0.0 4.5e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74471.1 - 9.2e-15 54.5 0.4 2e-14 53.4 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain GYF PF02213.16 GBG74471.1 - 2.5e-13 49.5 9.8 0.00039 20.0 0.1 4.8 4 0 0 4 4 4 4 GYF domain RT_RNaseH PF17917.1 GBG74471.1 - 8.9e-13 48.4 0.0 2.5e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74471.1 - 5.6e-07 29.5 0.0 1.5e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GYF_2 PF14237.6 GBG74471.1 - 6.2e-06 25.9 7.5 0.84 9.5 0.1 5.7 5 0 0 5 5 5 2 GYF domain 2 Chromo PF00385.24 GBG74471.1 - 0.0058 16.5 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG74471.1 - 0.14 12.4 1.3 0.25 11.6 0.1 2.1 2 0 0 2 2 2 0 H2C2 zinc finger SET PF00856.28 GBG74472.1 - 1.8e-20 74.0 0.3 8.5e-20 71.8 0.3 2.0 1 1 0 1 1 1 1 SET domain SET PF00856.28 GBG74473.1 - 8.6e-22 78.3 0.1 2.6e-21 76.8 0.1 1.7 1 1 0 1 1 1 1 SET domain DLEU7 PF15760.5 GBG74474.1 - 9 5.7 7.3 10 5.6 7.3 1.2 1 0 0 1 1 1 0 Leukemia-associated protein 7 RT_RNaseH_2 PF17919.1 GBG74475.1 - 2.1e-29 101.5 0.0 4e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74475.1 - 8e-28 96.8 0.0 1.3e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74475.1 - 3.2e-18 66.1 0.0 5.4e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OGG_N PF07934.12 GBG74475.1 - 0.16 12.1 0.1 0.47 10.6 0.0 1.7 2 0 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain PC-Esterase PF13839.6 GBG74476.1 - 1.4e-61 208.7 0.0 1.7e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 GBG74476.1 - 9.7e-15 54.6 9.4 9.7e-15 54.6 9.4 1.7 2 0 0 2 2 2 1 PMR5 N terminal Domain TPP_enzyme_N PF02776.18 GBG74477.1 - 5.1e-55 185.7 0.1 1.5e-53 180.9 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GBG74477.1 - 9.8e-47 158.6 0.0 4.8e-46 156.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GBG74477.1 - 8.3e-46 155.1 0.1 2e-45 153.9 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain SRP54 PF00448.22 GBG74478.1 - 2.6e-55 187.1 0.1 4.8e-55 186.2 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 GBG74478.1 - 3.8e-55 187.9 0.3 7.5e-55 186.9 0.1 1.6 1 1 1 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 GBG74478.1 - 1.2e-08 35.0 0.1 3.8e-08 33.4 0.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.6 GBG74478.1 - 6.3e-06 26.5 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG74478.1 - 0.00011 22.7 0.0 0.00043 20.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 GBG74478.1 - 0.0004 20.2 0.1 0.00089 19.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GBG74478.1 - 0.0021 18.5 0.2 0.022 15.2 0.0 2.6 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.12 GBG74478.1 - 0.0086 15.4 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 GBG74478.1 - 0.019 15.0 0.1 0.1 12.6 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 GBG74478.1 - 0.021 14.7 0.0 0.61 10.0 0.0 2.4 1 1 0 1 1 1 0 NTPase AAA_33 PF13671.6 GBG74478.1 - 0.032 14.4 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ETF PF01012.21 GBG74478.1 - 0.045 13.6 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Electron transfer flavoprotein domain MMR_HSR1 PF01926.23 GBG74478.1 - 0.048 13.8 1.1 0.58 10.3 1.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF190 PF02641.15 GBG74478.1 - 0.081 13.3 0.2 0.4 11.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, COG1993 ArsA_ATPase PF02374.15 GBG74478.1 - 0.093 11.9 0.5 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase NAD_binding_2 PF03446.15 GBG74479.1 - 2.1e-39 135.2 0.9 3.7e-39 134.4 0.9 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GBG74479.1 - 1.4e-28 99.6 1.0 1.4e-28 99.6 1.0 1.8 3 0 0 3 3 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GBG74479.1 - 6.3e-08 33.1 0.0 1.9e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 GBG74479.1 - 1.6e-05 24.6 0.0 4.3e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 GBG74479.1 - 4.2e-05 23.6 0.0 8.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 GBG74479.1 - 0.0012 18.4 0.0 0.004 16.7 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 GBG74479.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GBG74479.1 - 0.0019 18.1 0.1 0.0032 17.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 GBG74479.1 - 0.0043 17.0 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 GBG74479.1 - 0.0058 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GBG74479.1 - 0.043 13.3 0.2 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase TrkA_N PF02254.18 GBG74479.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PLD_C PF12357.8 GBG74480.1 - 2.8e-16 59.2 0.0 5.6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.22 GBG74480.1 - 5.2e-10 39.1 0.0 0.0018 18.4 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG74480.1 - 9.5e-08 32.0 0.0 8.4e-05 22.5 0.0 2.7 3 0 0 3 3 3 2 PLD-like domain TMEM171 PF15471.6 GBG74480.1 - 5.9 5.8 7.7 11 4.9 7.7 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Pro_isomerase PF00160.21 GBG74482.1 - 6.3e-22 78.5 0.1 1.5e-20 74.1 0.0 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 GBG74482.1 - 0.051 14.0 0.1 0.051 14.0 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) SecE PF00584.20 GBG74484.1 - 0.00061 19.7 1.0 0.00087 19.2 1.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Macoilin PF09726.9 GBG74484.1 - 0.39 9.2 3.3 0.48 8.9 3.3 1.2 1 0 0 1 1 1 0 Macoilin family FAM199X PF15814.5 GBG74484.1 - 1.5 7.8 16.3 2.8 6.9 16.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X WTX PF09422.10 GBG74485.1 - 0.0069 15.5 0.3 0.012 14.8 0.3 1.3 1 0 0 1 1 1 1 WTX protein DUF1664 PF07889.12 GBG74485.1 - 0.044 13.8 0.2 0.079 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 GBG74485.1 - 0.06 14.0 0.4 0.06 14.0 0.4 3.2 3 0 0 3 3 3 0 SlyX TolA_bind_tri PF16331.5 GBG74485.1 - 5.9 7.0 13.3 0.072 13.2 3.6 2.7 3 1 0 3 3 3 0 TolA binding protein trimerisation GDPD PF03009.17 GBG74486.1 - 9.2e-08 32.1 0.1 1.1e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 GBG74486.1 - 2.8e-06 27.6 0.3 6e-06 26.5 0.3 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Spt4 PF06093.13 GBG74486.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger BUD22 PF09073.10 GBG74486.1 - 0.037 13.4 5.0 0.039 13.3 5.0 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG74486.1 - 0.043 13.2 7.1 0.049 13.0 7.1 1.1 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.9 GBG74486.1 - 0.08 10.7 2.7 0.1 10.4 2.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CENP-B_dimeris PF09026.10 GBG74486.1 - 0.19 12.1 7.3 0.12 12.8 4.6 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RNA_pol_Rpc4 PF05132.14 GBG74486.1 - 0.3 11.5 2.6 0.44 11.0 2.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pox_Ag35 PF03286.14 GBG74486.1 - 0.41 10.4 6.7 0.57 9.9 6.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 GBG74486.1 - 0.48 11.1 8.6 1 10.1 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Usp PF00582.26 GBG74486.1 - 1.4 9.4 10.3 1.3 9.6 8.7 1.8 2 0 0 2 2 2 0 Universal stress protein family Sigma70_ner PF04546.13 GBG74486.1 - 1.7 8.5 12.3 2.6 7.9 12.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 GBG74486.1 - 2 6.4 15.2 2.6 6.0 15.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG74486.1 - 2.5 6.2 11.7 2.9 6.0 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG74486.1 - 3.2 7.5 10.0 31 4.3 10.8 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.16 GBG74486.1 - 4.1 6.5 6.9 5.6 6.1 6.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NARP1 PF12569.8 GBG74486.1 - 6.9 5.5 7.9 10 4.9 7.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPN2_C PF18004.1 GBG74486.1 - 9 6.2 10.9 17 5.3 10.9 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain rve PF00665.26 GBG74487.1 - 1.6e-14 54.1 0.0 4.2e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG74487.1 - 1.1e-07 31.9 0.9 1.8e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG74487.1 - 3.6e-05 23.9 0.1 8.8e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Spt46 PF17734.1 GBG74488.1 - 1.8 8.3 4.0 2.5 7.8 4.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 SPT6_acidic PF14632.6 GBG74488.1 - 5.4 7.7 20.2 0.12 12.9 11.9 2.0 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DDE_Tnp_4 PF13359.6 GBG74489.1 - 6.9e-09 35.6 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74489.1 - 0.0082 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein RT_RNaseH PF17917.1 GBG74490.1 - 4.2e-46 155.6 0.1 5.9e-23 81.2 0.1 3.1 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74490.1 - 6.2e-42 141.7 0.0 1.9e-23 82.3 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG74490.1 - 9.2e-35 119.8 0.1 1.9e-34 118.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG74490.1 - 3e-17 62.5 2.2 3.1e-17 62.4 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Dimer_Tnp_hAT PF05699.14 GBG74490.1 - 1.1e-09 37.9 0.2 3.2e-09 36.5 0.2 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region rve PF00665.26 GBG74490.1 - 6.9e-09 35.9 0.0 1.2e-07 32.0 0.0 2.8 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG74490.1 - 1.3e-07 31.4 1.4 0.039 13.9 0.0 4.2 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG74490.1 - 3.2e-07 30.9 0.0 7.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74490.1 - 1.9e-06 28.3 0.0 6.3e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74490.1 - 1.6e-05 24.7 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74490.1 - 0.0034 17.2 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease PFU PF09070.11 GBG74490.1 - 0.0041 17.4 0.0 0.025 14.8 0.0 2.2 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) Retrotrans_gag PF03732.17 GBG74490.1 - 0.017 15.4 8.2 0.49 10.7 0.0 4.6 5 0 0 5 5 5 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG74491.1 - 9.7e-32 110.3 0.1 1.7e-31 109.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74491.1 - 1.1e-29 102.4 0.0 2.6e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74491.1 - 1.2e-21 77.0 0.0 2.8e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74491.1 - 8.2e-17 61.1 0.1 2.8e-15 56.2 0.1 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG74491.1 - 6.2e-12 45.8 0.0 1.4e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74491.1 - 0.0005 20.2 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger CCDC85 PF10226.9 GBG74491.1 - 0.041 13.6 0.8 0.13 12.0 0.8 1.8 1 0 0 1 1 1 0 CCDC85 family DivIC PF04977.15 GBG74491.1 - 0.083 12.7 1.6 0.33 10.8 1.6 2.0 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 GBG74491.1 - 4.7 7.5 8.6 0.14 12.4 1.3 2.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 GBG74491.1 - 4.8 7.3 11.0 0.27 11.4 2.9 2.7 2 0 0 2 2 2 0 Basic region leucine zipper RVT_1 PF00078.27 GBG74492.1 - 2.2e-32 112.4 1.0 6e-28 97.9 0.1 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74492.1 - 1.1e-27 96.0 0.0 1.2e-22 79.8 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74492.1 - 2.4e-25 88.9 0.0 2.5e-21 75.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74492.1 - 9.2e-15 55.1 0.0 1.2e-06 29.1 0.0 3.7 3 0 0 3 3 3 2 Aspartyl protease RVP_2 PF08284.11 GBG74492.1 - 4.2e-13 49.2 0.0 0.0052 16.6 0.0 3.6 3 0 0 3 3 3 3 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG74492.1 - 2.2e-11 44.1 0.0 3.1e-05 24.4 0.0 3.5 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG74492.1 - 2.2e-07 30.7 0.0 0.026 14.3 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease Retrotrans_gag PF03732.17 GBG74492.1 - 0.0062 16.8 0.2 0.17 12.2 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein DMPK_coil PF08826.10 GBG74493.1 - 0.043 13.9 7.5 0.082 13.0 0.6 3.0 3 0 0 3 3 3 0 DMPK coiled coil domain like Flavi_DEAD PF07652.14 GBG74493.1 - 0.055 13.4 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Flavivirus DEAD domain EF-hand_1 PF00036.32 GBG74493.1 - 0.071 12.7 0.1 0.22 11.1 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 GBG74493.1 - 0.58 10.2 2.2 0.47 10.5 0.2 2.0 2 0 0 2 2 2 0 EF-hand domain gag-asp_proteas PF13975.6 GBG74494.1 - 5.7e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74494.1 - 0.00017 22.2 0.0 0.00043 20.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG74494.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74494.1 - 0.013 15.3 0.4 0.039 13.8 0.1 1.8 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG74495.1 - 3.1e-06 27.4 0.2 0.18 12.1 0.0 3.3 2 1 0 2 2 2 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG74495.1 - 0.00028 20.7 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease YL1 PF05764.13 GBG74495.1 - 0.0014 18.8 42.8 0.0014 18.8 42.8 4.9 4 1 0 4 4 4 1 YL1 nuclear protein Asp_protease_2 PF13650.6 GBG74495.1 - 0.0094 16.6 0.0 0.03 15.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74495.1 - 0.025 15.1 0.0 0.069 13.7 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF262 PF03235.14 GBG74495.1 - 0.39 10.9 9.4 0.95 9.6 9.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF262 RRN3 PF05327.11 GBG74495.1 - 8.7 4.8 12.7 17 3.8 12.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LSM PF01423.22 GBG74497.1 - 1.9e-21 75.5 2.4 2.1e-21 75.4 2.4 1.0 1 0 0 1 1 1 1 LSM domain HA2 PF04408.23 GBG74498.1 - 2e-19 69.9 5.0 2e-19 69.9 5.0 3.7 2 2 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GBG74498.1 - 4.4e-17 62.2 0.0 9e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GBG74498.1 - 1.2e-14 54.6 0.0 2.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GBG74498.1 - 2.5e-05 24.1 0.0 8.3e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GBG74498.1 - 8.2e-05 22.9 0.0 0.0003 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG74498.1 - 0.0011 18.7 0.1 0.0028 17.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG74498.1 - 0.0024 18.2 0.0 0.0086 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 GBG74498.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family CDC45 PF02724.14 GBG74498.1 - 0.026 12.9 13.5 0.03 12.6 2.9 2.2 2 0 0 2 2 2 0 CDC45-like protein T2SSE PF00437.20 GBG74498.1 - 0.029 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 GBG74498.1 - 0.036 13.5 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 GBG74498.1 - 0.13 12.2 4.2 9.3 6.2 0.0 3.5 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 GBG74498.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain C2 PF00168.30 GBG74499.1 - 2.5e-41 140.1 0.0 5.8e-24 84.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain VASt PF16016.5 GBG74499.1 - 1.7e-19 70.7 0.0 3.4e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GBG74499.1 - 2.4e-13 50.0 0.0 1.5e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 GRAM domain RT_RNaseH PF17917.1 GBG74501.1 - 2.2e-39 134.0 2.8 1.1e-18 67.4 0.1 3.2 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74501.1 - 5.6e-37 125.6 3.6 1.4e-17 63.5 0.2 3.0 3 0 0 3 3 3 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG74501.1 - 1.3e-28 100.0 0.0 2.3e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74501.1 - 3.9e-25 87.8 0.8 2.1e-11 43.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74501.1 - 1.7e-24 86.3 0.0 5.4e-12 46.0 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain RVP_2 PF08284.11 GBG74501.1 - 2.9e-06 27.1 0.0 6.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease VASt PF16016.5 GBG74501.1 - 0.00074 19.9 0.1 0.017 15.6 0.1 2.5 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain Asp_protease_2 PF13650.6 GBG74501.1 - 0.0029 18.2 0.0 0.0075 16.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74501.1 - 0.028 15.0 0.0 0.074 13.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG74501.1 - 0.033 14.1 0.2 0.033 14.1 0.2 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG74502.1 - 7.5e-05 23.3 0.0 0.00037 21.1 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74502.1 - 0.00014 22.3 0.2 0.00053 20.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG74502.1 - 0.033 14.4 0.8 15 5.9 0.0 3.5 3 1 0 3 3 3 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG74502.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF3006 PF11213.8 GBG74502.1 - 0.2 11.9 2.7 0.49 10.7 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) DUF4407 PF14362.6 GBG74502.1 - 2.4 7.4 12.2 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) INTS2 PF14750.6 GBG74503.1 - 6.1e-59 199.6 0.0 4.1e-48 163.7 0.5 4.4 4 0 0 4 4 4 4 Integrator complex subunit 2 IclR PF01614.18 GBG74504.1 - 6 6.7 11.6 7 6.5 0.5 2.4 2 0 0 2 2 2 0 Bacterial transcriptional regulator Pax7 PF12360.8 GBG74505.1 - 3.5 7.9 7.1 0.3 11.3 1.1 2.2 2 0 0 2 2 2 0 Paired box protein 7 Retrotrans_gag PF03732.17 GBG74506.1 - 0.001 19.3 1.8 0.0042 17.3 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein MRF_C1 PF13887.6 GBG74506.1 - 1.4 8.2 4.6 15 4.8 1.3 2.5 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 Retrotrans_gag PF03732.17 GBG74507.1 - 0.0032 17.7 0.0 0.015 15.5 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1664 PF07889.12 GBG74507.1 - 0.043 13.8 0.7 0.086 12.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 GBG74507.1 - 0.65 10.7 13.3 0.33 11.6 0.4 3.9 3 0 0 3 3 3 0 SlyX SpoIIP PF07454.11 GBG74507.1 - 3.2 7.1 16.0 2.9 7.3 11.8 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 GBG74507.1 - 3.7 6.5 15.3 0.065 12.2 6.8 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Pes-10 PF07149.11 GBG74507.1 - 6.3 5.7 31.4 12 4.8 31.4 1.3 1 0 0 1 1 1 0 Pes-10 RT_RNaseH_2 PF17919.1 GBG74508.1 - 7.3e-49 163.9 0.0 1.1e-26 92.8 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74508.1 - 5.4e-43 147.1 0.5 9.4e-31 107.0 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74508.1 - 5.7e-37 126.2 0.1 1.7e-26 92.5 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74508.1 - 3.5e-16 59.1 1.0 1.6e-15 56.9 0.7 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG74508.1 - 2.9e-12 46.8 0.0 4.2e-10 39.8 0.0 2.9 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG74508.1 - 1.2e-07 31.6 0.0 9.6e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74508.1 - 0.0013 19.3 0.0 0.0049 17.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74508.1 - 0.018 15.6 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Phage_GPO PF05929.11 GBG74508.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_lysozyme PF00959.19 GBG74509.1 - 0.011 16.1 0.7 0.066 13.7 0.0 2.4 2 1 0 2 2 2 0 Phage lysozyme RdRP PF05183.12 GBG74510.1 - 1.2e-35 123.3 0.1 1.8e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase TP53IP5 PF15331.6 GBG74510.1 - 1.9 8.6 8.3 3 8.0 8.3 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Presenilin PF01080.17 GBG74510.1 - 7.7 5.2 6.8 11 4.7 6.8 1.1 1 0 0 1 1 1 0 Presenilin RdRP PF05183.12 GBG74512.1 - 5.9e-133 444.6 0.0 8.7e-133 444.0 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RVT_1 PF00078.27 GBG74512.1 - 8.1e-09 35.3 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG74512.1 - 0.0019 18.4 8.7 0.021 15.1 0.0 4.5 5 0 0 5 5 5 2 Retrotransposon gag protein DUF4375 PF14300.6 GBG74512.1 - 0.59 10.4 7.9 0.95 9.7 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Use1 PF09753.9 GBG74512.1 - 1.2 8.8 10.4 3 7.5 10.4 1.6 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF87 PF01935.17 GBG74512.1 - 1.4 9.0 3.2 0.72 9.9 0.2 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain NSP2-B_epitope PF14757.6 GBG74513.1 - 0.17 11.5 7.6 0.49 10.0 7.8 1.7 1 1 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein RT_RNaseH_2 PF17919.1 GBG74514.1 - 4.7e-22 77.9 0.0 8.3e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74514.1 - 1e-20 74.0 0.0 2.3e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SET PF00856.28 GBG74514.1 - 6.2e-08 33.2 0.0 1.6e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 SET domain RVT_1 PF00078.27 GBG74514.1 - 2.3e-07 30.5 0.0 5.7e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ku_C PF03730.14 GBG74514.1 - 0.016 15.9 0.2 0.041 14.6 0.2 1.7 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm PEX-1N PF09262.11 GBG74514.1 - 0.048 14.1 0.6 0.23 11.9 0.2 2.2 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal RT_RNaseH_2 PF17919.1 GBG74515.1 - 1.6e-34 117.9 0.0 4.5e-34 116.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74515.1 - 1.2e-29 102.6 0.0 3.5e-29 101.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74515.1 - 9.6e-29 100.5 0.0 1.6e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74515.1 - 2.6e-15 56.3 0.1 6.1e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74515.1 - 3.2e-10 40.2 0.0 8.2e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG74515.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG74515.1 - 0.0097 16.2 1.7 0.018 15.3 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG74515.1 - 0.036 14.6 0.0 0.084 13.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.5 GBG74515.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Asp_protease_2 PF13650.6 GBG74515.1 - 0.081 13.6 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease eIF3_subunit PF08597.10 GBG74515.1 - 8 6.3 9.8 0.39 10.6 4.2 1.5 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit STAT_alpha PF01017.20 GBG74516.1 - 0.025 14.5 6.7 0.053 13.4 6.0 1.9 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF5401 PF17380.2 GBG74517.1 - 0.61 8.1 17.1 0.7 7.9 17.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DMPK_coil PF08826.10 GBG74517.1 - 1.1 9.4 13.5 95 3.2 0.2 2.7 1 1 1 2 2 2 0 DMPK coiled coil domain like DUF4820 PF16091.5 GBG74517.1 - 3.9 6.8 12.9 2.8 7.3 4.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4820) AAA_23 PF13476.6 GBG74517.1 - 4.2 7.8 9.5 0.53 10.8 4.1 2.0 2 0 0 2 2 2 0 AAA domain Retrotrans_gag PF03732.17 GBG74519.1 - 0.022 15.0 1.0 0.095 13.0 0.0 2.5 3 1 1 4 4 4 0 Retrotransposon gag protein DUF2781 PF10914.8 GBG74519.1 - 0.094 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) zf-HC5HC2H_2 PF13832.6 GBG74520.1 - 2.2e-27 95.4 30.0 7.9e-27 93.6 12.1 3.4 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GBG74520.1 - 1.5e-18 66.8 10.3 1.5e-18 66.8 10.3 4.2 3 1 1 4 4 4 2 PHD-like zinc-binding domain PHD_2 PF13831.6 GBG74520.1 - 1.6e-11 43.6 5.7 1.6e-11 43.6 5.7 4.0 4 0 0 4 4 4 2 PHD-finger PHD PF00628.29 GBG74520.1 - 3.3e-09 36.5 48.4 3.8e-07 29.9 9.0 4.2 4 0 0 4 4 4 2 PHD-finger PWWP PF00855.17 GBG74520.1 - 1.8e-07 31.4 0.7 4.9e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 PWWP domain RT_RNaseH_2 PF17919.1 GBG74520.1 - 0.00051 20.0 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG74520.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG74522.1 - 2.7e-12 46.7 0.0 4.6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG74522.1 - 2.3e-06 27.4 0.0 6.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74522.1 - 1.6e-05 25.4 0.0 3.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74522.1 - 0.00057 20.4 0.0 0.0027 18.2 0.0 2.2 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG74522.1 - 0.0022 17.8 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG74522.1 - 0.004 16.9 0.0 0.021 14.6 0.0 2.1 2 1 0 2 2 2 1 Aspartyl protease Mrr_N PF14338.6 GBG74522.1 - 0.13 12.4 3.5 14 5.9 2.4 3.0 2 0 0 2 2 2 0 Mrr N-terminal domain PHD PF00628.29 GBG74523.1 - 1e-12 47.7 31.1 5e-09 35.9 5.8 3.6 2 1 1 3 3 3 3 PHD-finger SET PF00856.28 GBG74524.1 - 4.9e-15 56.3 0.0 1.6e-14 54.7 0.0 2.0 1 0 0 1 1 1 1 SET domain zf-HC5HC2H_2 PF13832.6 GBG74524.1 - 5e-07 29.9 5.8 5e-07 29.9 5.8 3.4 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GBG74524.1 - 4e-05 23.8 9.2 4e-05 23.8 9.2 3.7 5 0 0 5 5 5 1 PHD-like zinc-binding domain FYRN PF05964.14 GBG74524.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 F/Y-rich N-terminus Pkinase PF00069.25 GBG74525.1 - 1e-42 146.4 0.0 1.8e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG74525.1 - 1.6e-42 145.6 0.0 3.4e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-bind_4 PF13837.6 GBG74525.1 - 0.0036 17.6 1.9 0.0058 17.0 0.5 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain PIP49_C PF12260.8 GBG74525.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 GBG74525.1 - 0.037 13.9 0.7 0.25 11.3 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 GBG74525.1 - 0.082 12.2 0.1 0.74 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like TPP_enzyme_C PF02775.21 GBG74526.1 - 9.4e-22 77.4 0.0 1.3e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RVT_1 PF00078.27 GBG74527.1 - 4.6e-14 52.5 0.0 9.5e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG74527.1 - 4e-07 30.6 0.0 9.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74527.1 - 2.7e-06 27.8 0.0 2.6e-05 24.7 0.0 2.5 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG74527.1 - 1.1e-05 25.6 1.4 0.23 11.8 0.0 3.4 2 0 0 2 2 2 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG74527.1 - 7.8e-05 22.5 0.1 0.052 13.3 0.0 3.4 2 1 1 3 3 3 1 Aspartyl protease RVP_2 PF08284.11 GBG74527.1 - 0.00016 21.4 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease rve PF00665.26 GBG74527.1 - 0.0024 18.1 0.0 0.016 15.4 0.0 2.4 1 0 0 1 1 1 1 Integrase core domain NPV_P10 PF05531.12 GBG74527.1 - 4.1 7.9 5.1 3.1e+02 1.9 5.5 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPP_enzyme_M PF00205.22 GBG74528.1 - 4.2e-21 75.1 0.0 5e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 GBG74528.1 - 0.024 14.4 0.0 0.036 13.9 0.0 1.3 1 1 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit RVT_1 PF00078.27 GBG74529.1 - 3.5e-29 101.9 0.1 5.9e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74529.1 - 7.7e-13 48.3 0.0 2.3e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74529.1 - 7.6e-08 32.9 0.0 2e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74529.1 - 2.2e-07 31.3 0.0 5.6e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74529.1 - 1.9e-06 27.7 0.0 4.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG74529.1 - 0.00051 20.3 0.7 0.072 13.4 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG74529.1 - 0.00062 20.0 0.0 0.002 18.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG74529.1 - 0.00064 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF4596 PF15363.6 GBG74529.1 - 0.48 10.7 3.1 1.4 9.2 3.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) DUF4407 PF14362.6 GBG74529.1 - 1.7 8.0 7.5 79 2.5 8.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Retrotrans_gag PF03732.17 GBG74530.1 - 0.04 14.2 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein TPP_enzyme_N PF02776.18 GBG74531.1 - 1e-28 100.1 0.0 1.5e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain BSD PF03909.17 GBG74532.1 - 1.2e-12 47.6 0.5 2.2e-12 46.8 0.5 1.4 1 0 0 1 1 1 1 BSD domain COPI_C PF06957.11 GBG74532.1 - 0.029 13.1 0.6 0.067 11.9 0.6 1.6 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus FXMRP1_C_core PF12235.8 GBG74532.1 - 0.15 12.7 0.1 0.15 12.7 0.1 3.1 3 1 0 3 3 3 0 Fragile X-related 1 protein core C terminal RVT_1 PF00078.27 GBG74533.1 - 2.1e-33 115.7 0.1 3.7e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74534.1 - 2e-25 89.1 0.0 6.7e-25 87.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74534.1 - 2.9e-22 79.3 0.0 5.4e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74534.1 - 1.4e-17 63.6 0.0 4.8e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG74534.1 - 9.4e-06 25.5 1.9 1.9e-05 24.5 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG74534.1 - 6.7e-05 22.6 2.4 6.7e-05 22.6 2.4 1.8 2 0 0 2 2 2 1 Zinc knuckle RVP_2 PF08284.11 GBG74534.1 - 0.00024 20.9 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG74534.1 - 0.015 15.8 0.1 0.034 14.7 0.1 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74534.1 - 0.016 15.8 0.0 0.041 14.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG74534.1 - 0.067 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease PALP PF00291.25 GBG74535.1 - 7.1e-67 225.9 0.7 1.2e-66 225.1 0.7 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF572 PF04502.13 GBG74536.1 - 1.8 8.1 23.3 2.3 7.8 23.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Myb_DNA-bind_4 PF13837.6 GBG74537.1 - 1.6e-06 28.4 0.5 4.6e-05 23.7 0.2 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG74538.1 - 1.3e-20 73.6 0.0 1.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74538.1 - 9e-13 48.3 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein ABC_tran_2 PF16949.5 GBG74538.1 - 0.24 10.2 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-binding cassette NOA36 PF06524.12 GBG74539.1 - 0.08 12.3 8.0 0.093 12.0 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.12 GBG74539.1 - 1 9.1 6.4 1 9.2 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nucleo_P87 PF07267.11 GBG74539.1 - 1.3 7.8 9.6 1.5 7.6 9.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PGA2 PF07543.12 GBG74539.1 - 1.8 8.6 12.3 2.4 8.1 12.3 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC45 PF02724.14 GBG74539.1 - 3.5 5.8 12.0 3.5 5.8 12.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG74539.1 - 4.2 5.5 14.7 4.3 5.4 14.7 1.0 1 0 0 1 1 1 0 Nop14-like family zf-CCCH PF00642.24 GBG74540.1 - 0.0052 16.7 0.6 0.0052 16.7 0.6 4.9 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DDE_Tnp_4 PF13359.6 GBG74541.1 - 9.1e-31 106.7 0.0 1.3e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74541.1 - 2.1e-13 50.4 0.0 3.2e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG74541.1 - 0.019 14.6 0.0 2.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Transposase DDE domain Carla_C4 PF01623.17 GBG74541.1 - 0.096 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein RT_RNaseH_2 PF17919.1 GBG74542.1 - 1.3e-20 73.3 0.0 2.5e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74542.1 - 2.3e-11 43.6 0.1 3.9e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74542.1 - 1.9e-08 34.6 0.0 4.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RXT2_N PF08595.11 GBG74543.1 - 0.37 10.8 6.3 0.27 11.2 3.8 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 GBG74543.1 - 0.41 8.7 7.1 0.59 8.2 7.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Sec5 PF15469.6 GBG74544.1 - 1.6e-45 155.2 0.8 1.2e-30 106.8 0.1 2.5 2 0 0 2 2 2 2 Exocyst complex component Sec5 RVT_1 PF00078.27 GBG74544.1 - 3.1e-29 102.1 0.1 6.6e-29 101.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74544.1 - 2.1e-27 95.1 0.0 1.4e-26 92.4 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74544.1 - 5.2e-23 81.3 0.0 3.1e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74544.1 - 3e-07 31.0 0.0 8.5e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74544.1 - 1.2e-06 28.9 0.0 4e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74544.1 - 1.1e-05 25.2 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Vps51 PF08700.11 GBG74544.1 - 1.5e-05 25.0 0.6 7.4e-05 22.8 0.1 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Asp_protease PF09668.10 GBG74544.1 - 0.00089 19.1 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease COG2 PF06148.11 GBG74544.1 - 0.074 13.1 0.9 0.46 10.6 0.3 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 GBG74544.1 - 0.32 10.2 4.5 0.094 12.0 0.6 2.0 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF4407 PF14362.6 GBG74544.1 - 3.7 6.8 13.8 0.86 8.9 9.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-CCHC PF00098.23 GBG74545.1 - 0.0073 16.3 3.2 0.013 15.6 3.2 1.4 1 0 0 1 1 1 1 Zinc knuckle DivIC PF04977.15 GBG74545.1 - 0.018 14.8 1.8 0.018 14.8 1.8 5.7 5 2 1 6 6 6 0 Septum formation initiator CCDC92 PF14916.6 GBG74545.1 - 0.029 14.1 12.3 18 5.2 0.1 5.4 2 1 3 5 5 5 0 Coiled-coil domain of unknown function RT_RNaseH_2 PF17919.1 GBG74546.1 - 4.1e-33 113.4 0.1 7e-33 112.6 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74546.1 - 1e-30 106.1 0.0 1.8e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74546.1 - 1.4e-06 28.3 0.0 3.9e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain Myb_DNA-bind_4 PF13837.6 GBG74547.1 - 9.3e-06 25.9 3.5 1.6e-05 25.2 3.5 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG74547.1 - 0.0054 16.8 2.2 0.0088 16.1 2.2 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Herpes_DNAp_acc PF04929.12 GBG74548.1 - 0.14 11.1 2.1 0.22 10.4 2.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Plasmodium_Vir PF05795.11 GBG74548.1 - 0.45 9.9 1.8 0.62 9.4 0.2 1.8 1 1 1 2 2 2 0 Plasmodium vivax Vir protein Metallophos PF00149.28 GBG74549.1 - 1.1e-36 127.2 0.1 1.7e-36 126.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GBG74549.1 - 0.00074 19.9 0.4 0.0016 18.9 0.4 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 GBG74549.1 - 0.073 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain MYCBPAP PF14646.6 GBG74550.1 - 0.11 11.5 0.2 0.79 8.6 0.1 1.9 2 0 0 2 2 2 0 MYCBP-associated protein family MazG_C PF18722.1 GBG74550.1 - 0.11 12.0 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 MazG C-terminal domain GGACT PF06094.12 GBG74551.1 - 2.3e-14 54.1 0.0 5.8e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 GBG74551.1 - 0.0079 16.6 0.2 0.048 14.1 0.0 2.3 3 0 0 3 3 3 1 AIG2-like family Usp PF00582.26 GBG74552.1 - 6.4e-50 169.3 0.5 3.9e-26 92.3 0.1 2.6 2 1 0 2 2 2 2 Universal stress protein family Ras PF00071.22 GBG74553.1 - 3e-30 105.0 0.0 5.3e-24 84.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GBG74553.1 - 3.1e-17 62.9 0.0 5.2e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG74553.1 - 4.2e-07 29.6 0.0 1.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GBG74553.1 - 0.056 13.3 0.0 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase DUF1198 PF06711.11 GBG74553.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) FAM184 PF15665.5 GBG74554.1 - 0.0028 17.5 0.3 0.0056 16.5 0.3 1.6 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B WD40 PF00400.32 GBG74555.1 - 8.1e-39 130.9 31.7 5.9e-06 26.9 0.1 13.3 13 0 0 13 13 13 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG74555.1 - 9.6e-11 41.8 4.9 0.26 11.6 0.1 7.3 5 2 1 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG74555.1 - 0.044 12.4 1.3 12 4.4 0.0 3.4 3 1 1 4 4 4 0 Nucleoporin Nup120/160 DUF4693 PF15764.5 GBG74556.1 - 2.8e-06 27.1 1.1 7.2e-06 25.8 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4693) BT1 PF03092.16 GBG74558.1 - 4.7e-86 289.1 10.1 3.6e-52 177.3 0.8 2.1 2 0 0 2 2 2 2 BT1 family BBS2_C PF14782.6 GBG74561.1 - 6.4e-119 397.5 0.2 5.3e-116 387.9 0.0 2.4 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 GBG74561.1 - 9.7e-42 141.4 0.0 1.1e-38 131.6 0.1 3.0 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 GBG74561.1 - 4.6e-36 122.9 0.0 2.5e-35 120.5 0.0 2.2 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal Itfg2 PF15907.5 GBG74561.1 - 7.3e-10 38.4 0.0 0.047 12.7 0.0 3.3 1 1 2 3 3 3 3 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 GBG74561.1 - 4.7e-08 33.0 0.1 0.00023 21.2 0.1 2.9 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.6 GBG74561.1 - 0.00014 22.4 0.8 0.027 15.1 0.2 2.8 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS1 PF14779.6 GBG74561.1 - 0.022 14.2 0.0 0.084 12.3 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 PQQ_2 PF13360.6 GBG74561.1 - 0.047 13.3 0.0 1.7 8.2 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain Eapp_C PF10238.9 GBG74564.1 - 0.00084 19.4 3.2 0.0014 18.7 3.2 1.3 1 0 0 1 1 1 1 E2F-associated phosphoprotein DDHD PF02862.17 GBG74564.1 - 0.0013 18.9 0.3 0.0018 18.5 0.3 1.2 1 0 0 1 1 1 1 DDHD domain NPR3 PF03666.13 GBG74564.1 - 0.002 17.0 0.2 0.0029 16.5 0.2 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF5308 PF17233.2 GBG74564.1 - 0.0056 16.9 0.2 0.0088 16.3 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5308) DUF3408 PF11888.8 GBG74564.1 - 0.0069 16.5 5.2 0.011 15.9 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3408) SpoIIP PF07454.11 GBG74564.1 - 0.0091 15.5 6.7 0.013 15.0 6.7 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) GOLD_2 PF13897.6 GBG74564.1 - 0.011 16.2 3.5 0.02 15.4 3.5 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking V_ATPase_I PF01496.19 GBG74564.1 - 0.016 13.2 3.2 0.021 12.8 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CPSF100_C PF13299.6 GBG74564.1 - 0.016 15.4 3.0 0.026 14.7 3.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 GBG74564.1 - 0.03 14.3 18.6 0.049 13.6 18.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 GBG74564.1 - 0.036 13.0 14.5 0.057 12.4 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spore_coat_CotO PF14153.6 GBG74564.1 - 0.051 13.5 11.8 0.076 12.9 11.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RPN2_C PF18004.1 GBG74564.1 - 0.053 13.4 8.4 0.082 12.8 8.4 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Serinc PF03348.15 GBG74564.1 - 0.055 12.4 1.8 0.1 11.5 1.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 GBG74564.1 - 0.16 11.7 6.1 0.31 10.8 6.1 1.4 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 GBG74564.1 - 0.2 11.3 9.9 0.32 10.6 9.9 1.2 1 0 0 1 1 1 0 FAM176 family FAM91_C PF14648.6 GBG74564.1 - 0.25 10.1 1.7 0.34 9.7 1.7 1.1 1 0 0 1 1 1 0 FAM91 C-terminus RPA43_OB PF17875.1 GBG74564.1 - 0.27 11.9 5.9 0.21 12.2 3.8 1.9 2 0 0 2 2 1 0 RPA43 OB domain in RNA Pol I RNA_pol_Rpc4 PF05132.14 GBG74564.1 - 0.35 11.3 7.6 0.64 10.4 7.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CSG2 PF16965.5 GBG74564.1 - 0.44 9.4 2.0 0.76 8.7 2.0 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator UPF0560 PF10577.9 GBG74564.1 - 0.51 8.8 14.1 0.71 8.3 14.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 eIF-3_zeta PF05091.12 GBG74564.1 - 0.52 9.2 11.1 0.72 8.8 11.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DNApol_Exo PF18136.1 GBG74564.1 - 0.58 9.2 6.5 0.92 8.6 6.5 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain PTPRCAP PF15713.5 GBG74564.1 - 0.91 9.8 16.6 1.7 8.9 16.6 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CCDC53 PF10152.9 GBG74564.1 - 1 9.8 9.8 2 8.8 9.8 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4407 PF14362.6 GBG74564.1 - 1 8.6 10.7 1.8 7.8 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_Ag35 PF03286.14 GBG74564.1 - 1.1 9.0 8.1 1.7 8.4 8.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4820 PF16091.5 GBG74564.1 - 1.2 8.5 7.8 1.8 7.9 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Folate_carrier PF01770.18 GBG74564.1 - 1.3 7.7 5.1 2 7.0 5.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier Presenilin PF01080.17 GBG74564.1 - 1.3 7.7 12.9 2.2 7.0 12.9 1.2 1 0 0 1 1 1 0 Presenilin FemAB PF02388.16 GBG74564.1 - 1.8 7.4 9.0 2.6 6.8 9.0 1.1 1 0 0 1 1 1 0 FemAB family DUF4746 PF15928.5 GBG74564.1 - 1.8 7.9 8.9 2.6 7.4 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GREB1 PF15782.5 GBG74564.1 - 2.3 5.2 6.7 3 4.8 6.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TERB2 PF15101.6 GBG74564.1 - 2.6 8.1 14.2 4.1 7.4 14.2 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 D123 PF07065.14 GBG74564.1 - 3 6.9 10.9 4.6 6.3 10.9 1.1 1 0 0 1 1 1 0 D123 TFB6 PF17110.5 GBG74564.1 - 3.2 7.5 8.5 5.8 6.6 8.5 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TRM13 PF05206.14 GBG74564.1 - 3.3 7.2 7.9 4.9 6.6 7.9 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Tim54 PF11711.8 GBG74564.1 - 3.6 6.3 11.7 2.4 6.9 10.0 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 AIF_C PF14721.6 GBG74564.1 - 3.7 7.9 11.4 6.4 7.2 11.4 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.12 GBG74564.1 - 6 6.6 14.6 9.2 6.0 14.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GBG74564.1 - 6.2 5.0 11.8 8.9 4.5 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 GBG74564.1 - 6.7 5.9 8.0 9.9 5.3 8.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 CobT PF06213.12 GBG74564.1 - 7 5.9 23.2 10 5.4 23.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PAT1 PF09770.9 GBG74564.1 - 8.2 4.6 16.9 11 4.1 16.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3464 PF11947.8 GBG74564.1 - 9.1 6.0 10.8 16 5.2 10.8 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RrnaAD PF00398.20 GBG74565.1 - 1.1e-61 208.3 0.0 1.4e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GBG74565.1 - 7.1e-08 33.0 0.0 1.4e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG74565.1 - 2.6e-05 24.8 0.0 5.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GBG74565.1 - 0.00013 21.7 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 GBG74565.1 - 0.00015 21.5 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PRMT5 PF05185.16 GBG74565.1 - 0.00026 20.9 0.1 0.0056 16.5 0.0 2.2 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 GBG74565.1 - 0.00053 20.7 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG74565.1 - 0.0012 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GBG74565.1 - 0.004 16.6 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 GBG74565.1 - 0.0046 16.5 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GBG74565.1 - 0.0076 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG74565.1 - 0.04 13.2 0.0 0.088 12.1 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PPS_PS PF02006.16 GBG74565.1 - 0.058 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase DREV PF05219.12 GBG74565.1 - 0.066 12.3 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.7 GBG74565.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 GBG74565.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Laminin_B PF00052.18 GBG74565.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Laminin B (Domain IV) Methyltransf_28 PF02636.17 GBG74565.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RVT_1 PF00078.27 GBG74566.1 - 2.6e-21 76.2 0.0 4.4e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SKI PF01202.22 GBG74567.1 - 0.00064 19.9 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase RNA_pol_Rpb2_3 PF04565.16 GBG74568.1 - 8.5e-24 83.5 0.1 1.7e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 GBG74568.1 - 5.8e-21 75.0 0.8 2.8e-19 69.5 0.8 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.15 GBG74568.1 - 1.5e-13 50.8 0.0 2.1e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit IPT PF01745.16 GBG74570.1 - 0.0036 16.7 0.1 0.0046 16.4 0.1 1.1 1 0 0 1 1 1 1 Isopentenyl transferase Myb_DNA-binding PF00249.31 GBG74571.1 - 2.5e-44 149.2 11.3 7.4e-18 64.5 0.8 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG74571.1 - 1.4e-34 118.1 11.3 3.4e-17 62.5 1.4 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GBG74571.1 - 0.00093 19.1 0.1 0.52 10.2 0.0 2.7 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 GBG74571.1 - 0.0011 19.0 0.1 0.43 10.6 0.0 2.3 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 GBG74571.1 - 0.23 11.7 0.3 3 8.1 0.0 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 GBG74572.1 - 2.4e-44 149.3 11.3 7.3e-18 64.5 0.8 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG74572.1 - 1.4e-34 118.2 11.3 3.3e-17 62.5 1.4 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GBG74572.1 - 0.0009 19.1 0.1 0.52 10.3 0.0 2.8 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 GBG74572.1 - 0.0011 19.0 0.1 0.43 10.6 0.0 2.4 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 GBG74572.1 - 0.22 11.7 0.3 2.9 8.1 0.0 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 GBG74573.1 - 1.8e-44 149.7 11.3 6.6e-18 64.6 0.8 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG74573.1 - 8.8e-35 118.8 11.3 3e-17 62.6 1.4 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GBG74573.1 - 0.00072 19.4 0.1 0.48 10.4 0.0 2.8 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 GBG74573.1 - 0.00089 19.3 0.1 0.39 10.8 0.0 2.4 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 GBG74573.1 - 0.18 12.0 0.3 2.7 8.2 0.0 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 RVT_1 PF00078.27 GBG74574.1 - 5.6e-29 101.2 0.1 1e-28 100.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74574.1 - 8.6e-22 77.1 0.0 4.4e-17 61.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74574.1 - 1.3e-14 54.0 0.3 2.7e-14 53.0 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG74574.1 - 3.4e-09 36.9 0.0 8.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG74574.1 - 0.0033 17.6 1.4 0.0064 16.7 0.2 2.2 2 0 0 2 2 2 1 H2C2 zinc finger Ribosomal_L34 PF00468.17 GBG74574.1 - 0.12 12.4 0.0 7.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L34 Piwi PF02171.17 GBG74575.1 - 5.8e-67 226.1 0.0 8.4e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain RVT_1 PF00078.27 GBG74575.1 - 1.8e-32 112.6 0.0 2.9e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG74575.1 - 0.0051 17.4 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG74576.1 - 4.5e-30 104.8 0.1 1e-29 103.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74576.1 - 2.8e-10 40.1 0.0 6.5e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG74576.1 - 0.0029 17.9 0.1 0.0029 17.9 0.1 3.4 4 0 0 4 4 4 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG74576.1 - 0.013 15.8 0.3 0.044 14.1 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74577.1 - 2e-32 112.5 0.1 4.1e-32 111.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArgoN PF16486.5 GBG74577.1 - 2.8e-26 92.8 0.0 5.7e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 GBG74577.1 - 1.6e-19 70.1 0.0 3.1e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.17 GBG74577.1 - 2.9e-18 66.2 0.0 6.5e-18 65.0 0.0 1.5 2 0 0 2 2 2 1 Piwi domain RT_RNaseH_2 PF17919.1 GBG74577.1 - 4.5e-18 65.1 0.0 2.1e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74577.1 - 4.4e-16 58.7 0.3 1.1e-15 57.5 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74577.1 - 1.8e-12 47.5 0.0 5e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain ArgoL1 PF08699.10 GBG74577.1 - 1.4e-11 43.9 0.0 3.1e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 GBG74577.1 - 1.2e-09 38.3 0.0 2.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 GBG74577.1 - 2.8e-09 37.1 0.1 1.5e-08 34.8 0.1 2.2 2 0 0 2 2 2 1 Mid domain of argonaute RT_RNaseH PF17917.1 GBG74577.1 - 2e-08 34.5 0.3 5.5e-05 23.4 0.0 3.0 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase Peptidase_C48 PF02902.19 GBG74578.1 - 9.7e-10 38.6 0.6 2e-09 37.6 0.6 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TPR_2 PF07719.17 GBG74579.1 - 8.1e-16 56.8 0.4 3.4e-06 26.7 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG74579.1 - 4.6e-15 54.7 0.4 8.9e-07 28.5 0.2 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG74579.1 - 4.1e-09 36.0 0.1 5.3e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 GBG74579.1 - 5.4e-08 33.4 0.0 0.00059 20.4 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG74579.1 - 1.5e-06 27.9 0.6 0.0023 18.0 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG74579.1 - 1.4e-05 25.1 0.2 0.16 12.4 0.1 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG74579.1 - 8.3e-05 23.1 0.0 0.7 10.9 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG74579.1 - 0.00012 22.5 1.3 0.029 15.0 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG74579.1 - 0.00053 20.4 0.2 0.2 12.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG74579.1 - 0.012 15.9 0.2 4.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG74579.1 - 0.11 12.6 0.0 0.94 9.7 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 GBG74579.1 - 0.14 12.5 0.5 1.8 8.9 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat NOP5NT PF08156.13 GBG74579.1 - 0.18 12.2 1.9 17 5.9 0.0 2.6 2 1 0 2 2 2 0 NOP5NT (NUC127) domain TOM20_plant PF06552.12 GBG74579.1 - 0.34 10.6 1.9 3.2 7.5 0.5 2.2 1 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DnaJ_C PF01556.18 GBG74581.1 - 1.3e-38 132.4 0.1 1.7e-38 132.0 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GBG74581.1 - 1.8e-29 101.6 3.1 2.7e-29 101.1 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain RVT_1 PF00078.27 GBG74583.1 - 3.5e-11 43.1 0.1 5.6e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74583.1 - 0.024 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG74583.1 - 0.21 9.8 8.1 0.25 9.5 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG74583.1 - 0.25 10.7 9.2 0.31 10.4 9.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG74583.1 - 0.57 8.4 7.6 0.73 8.1 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 GBG74583.1 - 0.77 10.0 12.9 1.2 9.4 12.9 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CHCH PF06747.13 GBG74584.1 - 6.9e-08 32.4 3.2 1.3e-07 31.6 3.2 1.5 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 GBG74584.1 - 0.00039 20.6 1.8 0.00096 19.3 1.8 1.6 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CX9C PF16860.5 GBG74584.1 - 0.0012 18.8 1.4 0.0021 18.0 1.4 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, V-ATPase_G PF03179.15 GBG74584.1 - 0.011 16.2 0.4 0.023 15.2 0.4 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit RVT_1 PF00078.27 GBG74585.1 - 3.1e-28 98.8 0.3 6.6e-28 97.7 0.3 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 GBG74585.1 - 0.24 11.2 0.0 0.44 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF659 PF04937.15 GBG74586.1 - 7.7e-32 110.3 0.0 1.3e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG74586.1 - 6.9e-07 29.0 0.1 1.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ints3 PF10189.9 GBG74587.1 - 2.5e-82 275.5 0.0 3.7e-82 275.0 0.0 1.3 1 0 0 1 1 1 1 Integrator complex subunit 3 DUF3586 PF12131.8 GBG74587.1 - 0.25 11.6 1.1 0.45 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) RRM_1 PF00076.22 GBG74588.1 - 4.9e-22 77.5 0.2 3.2e-09 36.5 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GBG74588.1 - 9.1e-14 51.1 0.3 1.7e-07 30.9 0.0 4.1 2 2 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 GBG74588.1 - 8.5e-11 41.9 0.2 1.3e-07 31.7 0.0 3.4 3 0 0 3 3 3 1 RRM-like domain RRM_occluded PF16842.5 GBG74588.1 - 0.0026 17.6 0.0 5.5 6.9 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif SEP PF08059.13 GBG74588.1 - 0.12 12.9 0.0 15 6.3 0.0 2.5 2 0 0 2 2 2 0 SEP domain RRM_1 PF00076.22 GBG74589.1 - 5e-22 77.5 0.2 3.2e-09 36.5 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GBG74589.1 - 5.2e-13 48.7 0.4 8.7e-07 28.6 0.0 4.1 2 2 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 GBG74589.1 - 8.2e-11 42.0 0.1 1.3e-07 31.7 0.0 3.4 3 0 0 3 3 3 1 RRM-like domain RRM_occluded PF16842.5 GBG74589.1 - 0.0026 17.6 0.0 5.5 6.9 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif SEP PF08059.13 GBG74589.1 - 0.12 12.9 0.0 15 6.3 0.0 2.5 2 0 0 2 2 2 0 SEP domain DUF659 PF04937.15 GBG74590.1 - 6.8e-14 52.0 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG74590.1 - 0.0061 16.3 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pro_isomerase PF00160.21 GBG74591.1 - 3.7e-34 118.3 0.3 2.6e-32 112.3 0.3 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BOP1NT PF08145.12 GBG74592.1 - 7.2e-108 360.4 13.0 1.1e-107 359.8 13.0 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 GBG74592.1 - 2.5e-25 88.2 4.3 4.5e-09 36.8 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG74592.1 - 1.2e-06 28.7 0.1 0.0076 16.5 0.0 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG74592.1 - 0.089 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Cys_Knot_tox PF17486.2 GBG74593.1 - 0.2 11.9 0.7 0.5 10.6 0.7 1.6 1 0 0 1 1 1 0 Cystine knot toxins BBS2_Mid PF14783.6 GBG74594.1 - 0.15 12.1 0.0 26 4.9 0.0 2.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 GBG74594.1 - 0.23 12.4 0.1 0.23 12.4 0.1 5.4 5 0 0 5 5 5 0 WD domain, G-beta repeat DDE_1 PF03184.19 GBG74595.1 - 7e-11 42.1 0.2 2.4e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 GBG74595.1 - 2.3e-09 37.1 0.8 4.4e-09 36.3 0.1 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 GBG74595.1 - 3.2e-06 27.3 2.5 1e-05 25.7 0.2 2.4 2 0 0 2 2 2 1 Transposase CENP-B_N PF04218.13 GBG74595.1 - 0.0022 17.6 0.0 0.0056 16.3 0.0 1.8 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DUF4207 PF13904.6 GBG74595.1 - 0.02 14.6 1.5 0.03 14.0 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) LptF_LptG PF03739.14 GBG74596.1 - 0.029 13.2 0.1 0.034 13.0 0.1 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG zf-NF-X1 PF01422.17 GBG74597.1 - 3.5e-13 49.3 86.3 2.4e-07 30.7 16.2 11.7 12 0 0 12 12 12 6 NF-X1 type zinc finger R3H PF01424.22 GBG74597.1 - 0.003 17.5 0.0 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 R3H domain Methyltransf_7 PF03492.15 GBG74598.1 - 9.4e-67 225.6 0.0 1.9e-59 201.6 0.0 2.2 2 0 0 2 2 2 2 SAM dependent carboxyl methyltransferase Peptidase_C48 PF02902.19 GBG74598.1 - 3.9e-20 72.6 0.0 8.9e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RVT_1 PF00078.27 GBG74600.1 - 6.5e-25 87.9 0.1 1.1e-24 87.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG74600.1 - 3.4e-12 46.1 0.0 6.3e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG74600.1 - 1.5e-11 44.6 0.0 5.6e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp-B-Hydro_N PF05279.11 GBG74601.1 - 2.3 8.2 21.4 2.8 8.0 21.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CP12 PF02672.15 GBG74602.1 - 2e-22 79.7 3.8 2.8e-22 79.2 3.8 1.2 1 0 0 1 1 1 1 CP12 domain Med26_M PF15694.5 GBG74602.1 - 0.059 13.4 0.4 0.076 13.1 0.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain Apolipoprotein PF01442.18 GBG74602.1 - 0.066 13.1 0.3 0.12 12.2 0.3 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain MCR PF18509.1 GBG74603.1 - 0.016 14.8 0.8 0.031 13.9 0.8 1.5 1 0 0 1 1 1 0 Magnetochrome domain Pkinase PF00069.25 GBG74604.1 - 1.5e-72 244.1 0.0 1.9e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG74604.1 - 1.8e-33 115.9 0.0 2.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG74604.1 - 3.1e-06 26.7 0.0 0.00093 18.6 0.0 2.2 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 GBG74604.1 - 3.4e-06 26.6 0.1 5.1e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GBG74604.1 - 0.00078 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GBG74604.1 - 0.0067 16.4 0.1 0.27 11.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family TrkH PF02386.16 GBG74605.1 - 5.6e-60 203.2 16.7 4.1e-49 167.4 11.7 3.6 3 1 0 3 3 3 3 Cation transport protein SbmA_BacA PF05992.12 GBG74606.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 SbmA/BacA-like family Myb_DNA-bind_4 PF13837.6 GBG74607.1 - 1.7e-07 31.5 5.2 1.7e-07 31.5 5.2 2.4 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG74607.1 - 0.0024 18.1 5.9 0.012 15.9 2.9 2.6 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG74607.1 - 0.0065 16.5 2.0 0.013 15.5 2.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG74607.1 - 0.025 14.8 0.6 1.5 9.0 0.6 2.9 3 0 0 3 3 3 0 Myb-like DNA-binding domain PHD_3 PF13922.6 GBG74607.1 - 0.072 13.5 1.3 0.2 12.1 1.3 1.8 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Myb_DNA-bind_4 PF13837.6 GBG74609.1 - 5.3e-09 36.3 4.7 1.5e-08 34.9 2.7 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG74609.1 - 0.00023 21.4 1.5 0.0043 17.3 0.4 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG74609.1 - 0.0008 19.6 1.4 0.0015 18.7 1.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG74609.1 - 0.0013 18.9 0.5 0.0028 17.8 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG74609.1 - 0.0066 16.5 0.6 0.012 15.7 0.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG74610.1 - 9.4e-32 110.3 0.1 1.4e-31 109.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74610.1 - 1e-30 105.7 0.0 2.4e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74610.1 - 2.8e-26 91.9 0.0 5.7e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CTP_transf_1 PF01148.20 GBG74610.1 - 0.063 13.0 8.6 0.21 11.3 8.6 1.9 1 1 0 1 1 1 0 Cytidylyltransferase family YvrJ PF12841.7 GBG74610.1 - 4.7 6.8 4.6 0.84 9.2 0.6 1.9 2 0 0 2 2 2 0 YvrJ protein family RVT_1 PF00078.27 GBG74611.1 - 9.6e-32 110.3 0.1 1.4e-31 109.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74611.1 - 1.1e-30 105.6 0.0 2.5e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74611.1 - 2.8e-26 91.8 0.0 5.9e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CTP_transf_1 PF01148.20 GBG74611.1 - 0.002 18.0 5.5 0.0057 16.5 5.5 1.8 1 0 0 1 1 1 1 Cytidylyltransferase family YvrJ PF12841.7 GBG74611.1 - 3.9 7.1 4.3 0.85 9.2 0.6 1.9 2 0 0 2 2 2 0 YvrJ protein family Neur_chan_LBD PF02931.23 GBG74612.1 - 2.5e-06 27.1 0.0 0.0081 15.6 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain ERAP1_C PF11838.8 GBG74615.1 - 1.1e-15 58.0 0.1 1.3e-15 57.8 0.1 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 GBG74616.1 - 5.5e-87 290.9 0.0 6.9e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 GBG74616.1 - 1.8e-11 44.2 0.0 1.3e-05 24.9 0.0 2.3 1 1 1 2 2 2 2 ERAP1-like C-terminal domain DUF45 PF01863.17 GBG74616.1 - 0.072 13.1 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF45 Aminopep PF10023.9 GBG74616.1 - 0.097 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative aminopeptidase DUF4200 PF13863.6 GBG74617.1 - 3e-35 121.2 17.6 3e-35 121.2 17.6 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4200) OmpH PF03938.14 GBG74617.1 - 0.012 16.0 2.9 0.012 16.0 2.9 4.4 4 1 0 4 4 4 0 Outer membrane protein (OmpH-like) Lectin_N PF03954.14 GBG74617.1 - 0.93 9.2 5.5 0.38 10.5 0.3 2.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.12 GBG74617.1 - 1.4 9.0 3.3 20 5.2 0.6 3.1 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc42p PF11544.8 GBG74617.1 - 2.4 8.2 12.7 0.52 10.4 0.3 4.3 3 0 0 3 3 3 0 Spindle pole body component Spc42p Tugs PF17840.1 GBG74617.1 - 5.4 7.3 9.2 42 4.4 0.2 3.1 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain RVT_1 PF00078.27 GBG74618.1 - 2.9e-36 125.1 0.1 4.5e-36 124.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74618.1 - 6.4e-28 96.7 0.0 1.5e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74618.1 - 3.7e-27 94.7 0.0 7.5e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74618.1 - 7.1e-09 35.6 0.1 2.3e-08 34.0 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG74618.1 - 0.33 10.5 0.0 0.33 10.5 0.0 1.9 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FKBP_C PF00254.28 GBG74619.1 - 1.3e-24 86.3 0.0 1.5e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Myb_DNA-bind_4 PF13837.6 GBG74622.1 - 5.1e-09 36.4 3.1 6.3e-09 36.1 1.2 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG74622.1 - 0.027 14.8 0.4 0.068 13.5 0.4 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like gag-asp_proteas PF13975.6 GBG74624.1 - 0.0024 18.4 0.0 0.0056 17.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG74624.1 - 0.016 15.5 0.3 0.034 14.4 0.3 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein RVP PF00077.20 GBG74624.1 - 0.03 14.6 0.0 0.086 13.2 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease AT_hook PF02178.19 GBG74625.1 - 0.014 15.2 1.4 0.014 15.2 1.4 5.1 6 0 0 6 6 6 0 AT hook motif DUF4296 PF14129.6 GBG74627.1 - 0.026 15.1 2.7 0.2 12.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4296) Aminopep PF10023.9 GBG74627.1 - 0.25 10.7 10.3 0.35 10.2 10.3 1.4 1 1 0 1 1 1 0 Putative aminopeptidase DUF2514 PF10721.9 GBG74627.1 - 5.2 7.1 18.3 12 6.0 18.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) WD40 PF00400.32 GBG74628.1 - 4e-15 56.0 3.2 6.7e-05 23.6 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG74628.1 - 3.6e-07 30.4 0.3 0.0017 18.6 0.0 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Shugoshin_N PF07558.11 GBG74628.1 - 0.066 13.1 0.9 0.14 12.0 0.9 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region RT_RNaseH_2 PF17919.1 GBG74629.1 - 1.6e-34 117.9 0.9 6.2e-34 116.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74629.1 - 2.8e-30 104.7 0.1 2.8e-30 104.7 0.1 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74629.1 - 2e-16 60.3 0.0 9.9e-16 58.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain DUF1564 PF07600.11 GBG74629.1 - 0.067 12.9 0.3 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Chromo PF00385.24 GBG74629.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain HTH_29 PF13551.6 GBG74632.1 - 0.017 15.1 1.6 0.043 13.8 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn helix Spc7 PF08317.11 GBG74632.1 - 0.16 10.8 13.8 0.55 9.1 1.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein CP12 PF02672.15 GBG74632.1 - 1.8 9.4 6.1 6.7 7.6 0.3 3.5 4 0 0 4 4 4 0 CP12 domain HAUS-augmin3 PF14932.6 GBG74632.1 - 3.5 7.1 9.6 0.44 10.1 1.0 2.4 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 GBG74632.1 - 9.4 6.9 10.1 16 6.2 0.3 3.2 2 1 0 2 2 2 0 Initiation control protein YabA Tim17 PF02466.19 GBG74633.1 - 8.9e-28 96.9 8.6 1.1e-27 96.6 8.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 GBG74633.1 - 1.2 9.6 11.6 3 8.3 7.6 2.8 1 1 2 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 RVT_1 PF00078.27 GBG74635.1 - 3e-21 76.0 0.0 6.5e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74635.1 - 8e-13 48.3 0.4 1.8e-12 47.2 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG74635.1 - 1.4e-07 31.4 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74635.1 - 2.8e-06 27.9 0.0 6.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74635.1 - 6.9e-05 23.3 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG74635.1 - 0.00079 19.2 0.1 0.0029 17.4 0.0 1.8 2 0 0 2 2 2 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG74635.1 - 0.042 14.1 0.0 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 H2C2 zinc finger Thioredoxin PF00085.20 GBG74636.1 - 1.1e-52 176.4 0.1 5.1e-26 90.6 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin RVT_1 PF00078.27 GBG74636.1 - 2.1e-28 99.3 0.0 4.3e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74636.1 - 1e-22 80.0 0.0 2.5e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74636.1 - 2.7e-19 69.4 0.0 6.8e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Thioredoxin_2 PF13098.6 GBG74636.1 - 0.00012 22.5 0.0 0.04 14.4 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin-like domain Retrotrans_gag PF03732.17 GBG74636.1 - 0.0003 21.0 0.5 0.0035 17.6 0.3 3.0 1 1 1 2 2 2 1 Retrotransposon gag protein Thioredoxin_8 PF13905.6 GBG74636.1 - 0.0074 16.6 0.2 6.6 7.1 0.0 4.1 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_6 PF13848.6 GBG74636.1 - 0.027 14.4 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like domain PBECR2 PF18810.1 GBG74636.1 - 0.17 12.2 0.4 74 3.7 0.0 4.0 5 0 0 5 5 5 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 DDE_Tnp_4 PF13359.6 GBG74637.1 - 5.3e-28 97.7 0.0 1.5e-27 96.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74637.1 - 1.1e-14 54.5 0.0 1.7e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG74637.1 - 0.0015 18.2 0.4 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG74637.1 - 0.01 16.2 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG74638.1 - 2.8e-08 34.0 2.2 7.8e-08 32.6 2.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG74638.1 - 2e-05 24.7 0.1 0.0034 17.5 0.4 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG74638.1 - 0.0011 19.1 1.6 0.0034 17.6 1.6 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG74638.1 - 0.004 17.4 0.4 0.0083 16.4 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG74638.1 - 0.022 14.8 0.7 0.041 14.0 0.7 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ThiF PF00899.21 GBG74639.1 - 6.9e-60 202.4 0.0 1.1e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 GBG74639.1 - 2.3e-10 40.9 0.0 5.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 GBG74639.1 - 0.01 16.1 1.2 0.029 14.6 1.2 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 GBG74639.1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 GBG74639.1 - 0.097 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 GBG74639.1 - 0.1 11.8 0.3 0.17 11.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain PglD_N PF17836.1 GBG74639.1 - 0.11 13.2 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 PglD N-terminal domain CDC45 PF02724.14 GBG74639.1 - 0.11 10.7 7.6 0.18 10.1 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GBG74639.1 - 3.5 6.0 6.4 4.9 5.6 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TPR_12 PF13424.6 GBG74642.1 - 4.4e-09 36.5 5.3 0.012 15.8 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG74642.1 - 1e-06 28.4 4.2 0.13 12.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 GBG74642.1 - 2.6e-05 24.0 11.9 5.7e-05 22.9 11.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.28 GBG74642.1 - 0.00031 20.4 0.0 0.6 10.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG74642.1 - 0.00067 19.5 0.0 0.34 11.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG74642.1 - 0.0012 18.5 0.0 0.7 9.6 0.1 2.5 2 0 0 2 2 2 2 TPR repeat zf-RING_2 PF13639.6 GBG74642.1 - 0.0027 18.0 12.1 0.0076 16.6 12.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG74642.1 - 0.007 16.3 11.1 0.014 15.3 11.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 GBG74642.1 - 0.011 15.9 6.2 0.021 15.0 6.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 TPR_10 PF13374.6 GBG74642.1 - 0.012 15.4 5.4 1.6 8.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 GBG74642.1 - 0.015 15.1 10.0 0.015 15.1 10.0 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 TPR_MalT PF17874.1 GBG74642.1 - 0.034 13.5 0.4 1.9 7.8 0.1 2.7 3 0 0 3 3 3 0 MalT-like TPR region zf-C3HC4 PF00097.25 GBG74642.1 - 0.04 13.8 11.6 0.081 12.8 11.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG74642.1 - 0.72 9.9 8.9 1.7 8.7 8.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 GBG74642.1 - 9.4 6.4 11.3 19 5.4 11.3 1.6 1 0 0 1 1 1 0 Zinc-finger RVT_1 PF00078.27 GBG74644.1 - 2.9e-09 36.8 0.0 4.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CTP_transf_like PF01467.26 GBG74645.1 - 1.7e-31 109.3 0.0 6.6e-25 88.0 0.0 2.2 1 1 1 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 GBG74645.1 - 0.0091 15.9 0.1 0.12 12.3 0.1 2.2 1 1 0 1 1 1 1 FAD synthetase RRM_1 PF00076.22 GBG74646.1 - 3.1e-39 132.6 0.0 6e-18 64.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG74646.1 - 7e-07 29.3 0.0 0.011 15.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM PF05172.13 GBG74646.1 - 7.7e-06 25.8 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 GBG74646.1 - 0.00024 21.0 0.0 0.3 11.1 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GBG74646.1 - 0.034 14.2 0.2 5.8 7.0 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Prominin PF05478.11 GBG74648.1 - 0.26 9.2 0.3 0.43 8.5 0.3 1.2 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 GBG74648.1 - 0.31 9.9 15.2 0.72 8.7 1.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 GBG74648.1 - 0.37 11.0 19.4 0.93 9.7 4.5 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 GBG74648.1 - 0.98 9.8 11.9 4.4 7.7 4.9 2.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 GBG74648.1 - 2 7.7 11.2 0.71 9.2 8.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HALZ PF02183.18 GBG74648.1 - 5.3 7.3 12.8 7.3 6.9 0.6 4.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 GBG74648.1 - 8.2 6.7 21.5 0.94 9.7 3.4 3.2 3 2 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1690 PF07956.11 GBG74648.1 - 8.7 6.8 11.5 0.93 9.9 4.3 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Cation_ATPase_C PF00689.21 GBG74649.1 - 1.4e-35 122.7 0.2 3.3e-17 62.8 0.3 2.2 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GBG74649.1 - 5.5e-18 66.0 0.1 6.8e-17 62.5 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GBG74649.1 - 3.8e-16 58.9 0.0 8.2e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 GBG74649.1 - 2.4e-05 24.8 0.2 0.00019 21.9 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GBG74649.1 - 3.6e-05 23.6 1.2 0.027 14.2 0.3 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HOOK PF05622.12 GBG74650.1 - 3.3e-12 45.4 43.5 3.3e-12 45.4 43.5 3.8 2 1 0 3 3 3 2 HOOK protein TMCO5 PF14992.6 GBG74650.1 - 0.0015 18.2 28.0 0.0015 18.2 28.0 4.3 2 1 3 5 5 5 1 TMCO5 family BLOC1_2 PF10046.9 GBG74650.1 - 0.005 17.1 5.5 0.005 17.1 5.5 6.5 3 2 3 6 6 6 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Par3_HAL_N_term PF12053.8 GBG74650.1 - 0.17 12.1 3.0 0.7 10.1 0.2 3.4 3 0 0 3 3 3 0 N-terminal of Par3 and HAL proteins NPV_P10 PF05531.12 GBG74650.1 - 1.4 9.5 32.1 1.3 9.6 0.7 7.4 5 2 0 6 6 6 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 GBG74650.1 - 1.4 8.9 113.8 0.17 11.9 23.8 6.7 2 2 5 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RasGEF_N_2 PF14663.6 GBG74650.1 - 5.1 7.5 11.2 0.32 11.4 0.7 3.3 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Prp19 PF08606.11 GBG74650.1 - 6.3 6.9 11.4 0.69 9.9 1.3 3.7 2 1 0 3 3 3 0 Prp19/Pso4-like TPR_MLP1_2 PF07926.12 GBG74650.1 - 6.8 6.8 124.3 0.065 13.3 4.7 8.5 3 3 3 8 8 8 0 TPR/MLP1/MLP2-like protein Ank_4 PF13637.6 GBG74651.1 - 1.2e-15 57.6 0.2 4.9e-13 49.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GBG74651.1 - 1.3e-14 54.5 0.0 1.5e-13 51.1 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) PARP PF00644.20 GBG74651.1 - 4.3e-12 46.0 0.0 1.2e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Ank PF00023.30 GBG74651.1 - 3.1e-11 43.2 0.9 7.3e-06 26.2 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GBG74651.1 - 4.7e-11 42.7 0.9 4.6e-09 36.3 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG74651.1 - 8.7e-11 41.1 0.1 0.00072 19.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat WWE PF02825.20 GBG74651.1 - 0.02 15.4 0.0 0.045 14.3 0.0 1.6 1 0 0 1 1 1 0 WWE domain RVT_1 PF00078.27 GBG74652.1 - 5.6e-34 117.6 0.0 8.1e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FoP_duplication PF13865.6 GBG74652.1 - 2.3 8.8 8.9 5.6 7.6 8.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Usp PF00582.26 GBG74653.1 - 4.1e-17 63.0 0.0 1.8e-15 57.7 0.0 2.2 2 0 0 2 2 2 1 Universal stress protein family SPX PF03105.19 GBG74653.1 - 0.59 10.0 2.6 0.67 9.8 2.6 1.0 1 0 0 1 1 1 0 SPX domain Xin PF08043.12 GBG74653.1 - 9.3 6.1 6.7 0.35 10.6 0.7 1.8 2 0 0 2 2 2 0 Xin repeat RVT_1 PF00078.27 GBG74655.1 - 1.3e-25 90.3 0.0 2e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74655.1 - 1.3e-24 86.1 0.0 2.8e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74655.1 - 2.1e-22 79.4 0.0 4.4e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74655.1 - 1.6e-17 63.3 0.1 3.8e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG74655.1 - 1.5e-06 28.0 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74655.1 - 0.00024 21.7 0.0 0.00057 20.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG74655.1 - 0.00026 21.1 0.0 0.00095 19.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG74655.1 - 0.00028 21.4 0.0 0.00069 20.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG74656.1 - 3.6e-05 23.6 1.8 8.4e-05 22.5 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG74656.1 - 0.0073 16.1 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG74656.1 - 0.072 13.1 0.8 0.072 13.1 0.8 2.6 3 1 0 3 3 3 0 Zinc knuckle DUF2514 PF10721.9 GBG74656.1 - 0.44 10.6 13.9 0.82 9.7 13.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) FUSC PF04632.12 GBG74656.1 - 0.73 8.3 9.1 0.82 8.1 9.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Connexin PF00029.19 GBG74656.1 - 2 8.1 7.1 3.1 7.5 7.1 1.4 1 0 0 1 1 1 0 Connexin ALMT PF11744.8 GBG74656.1 - 3.7 6.3 7.2 4.3 6.1 7.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 GBG74656.1 - 4.4 5.1 7.4 4.8 5.0 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rad60-SLD_2 PF13881.6 GBG74656.1 - 7 6.8 8.0 0.18 11.9 0.7 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like AAA_23 PF13476.6 GBG74657.1 - 0.26 11.7 1.3 0.63 10.5 1.3 1.6 1 0 0 1 1 1 0 AAA domain Brix PF04427.18 GBG74658.1 - 3.5e-24 86.0 0.1 3.5e-24 86.0 0.1 1.6 2 0 0 2 2 2 1 Brix domain MAS20 PF02064.15 GBG74658.1 - 0.034 14.2 0.5 0.064 13.4 0.5 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor RBM39linker PF15519.6 GBG74658.1 - 0.057 14.5 0.3 0.1 13.7 0.3 1.3 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein DDE_Tnp_4 PF13359.6 GBG74659.1 - 1e-56 191.0 0.0 5.2e-30 104.2 0.0 2.7 2 0 0 2 2 2 2 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 GBG74659.1 - 2.3e-25 88.5 0.0 5.1e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Plant_tran PF04827.14 GBG74659.1 - 6.3e-25 88.0 0.0 1.8e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Plant transposon protein RT_RNaseH PF17917.1 GBG74659.1 - 3.3e-20 72.3 0.0 7.5e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74659.1 - 0.0005 19.6 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3761 PF12587.8 GBG74659.1 - 0.044 14.2 0.5 0.26 11.8 0.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) DDE_Tnp_1 PF01609.21 GBG74659.1 - 0.29 10.7 6.9 4.6 6.8 0.0 4.5 5 0 0 5 5 5 0 Transposase DDE domain Lzipper-MIP1 PF14389.6 GBG74660.1 - 0.034 14.5 2.2 0.61 10.4 0.2 3.0 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Com_YlbF PF06133.11 GBG74660.1 - 0.041 14.5 8.3 0.062 13.9 4.5 2.5 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA ATG16 PF08614.11 GBG74660.1 - 0.056 13.7 9.7 1.2 9.4 5.3 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 GBG74660.1 - 0.18 10.3 1.7 0.22 10.0 1.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family GPS2_interact PF15784.5 GBG74660.1 - 0.36 11.3 13.0 0.24 11.9 1.1 3.3 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain DUF724 PF05266.14 GBG74660.1 - 0.79 9.5 7.5 0.49 10.2 4.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.7 GBG74660.1 - 0.95 9.6 10.6 2.4 8.3 9.0 2.4 1 1 1 2 2 2 0 Tropomyosin like DUF2968 PF11180.8 GBG74660.1 - 3.7 7.1 11.8 2.7 7.6 8.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Csm1_N PF18504.1 GBG74660.1 - 6.3 7.2 10.8 4.8 7.6 1.9 3.3 3 1 1 4 4 4 0 Csm1 N-terminal domain DUF4235 PF14019.6 GBG74661.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) RVT_1 PF00078.27 GBG74663.1 - 3.2e-32 111.9 0.1 5.5e-32 111.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74663.1 - 9.9e-29 99.3 0.0 3.2e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74663.1 - 2.6e-27 95.1 0.0 5.8e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG74663.1 - 8.5e-16 58.0 0.0 1.6e-14 53.9 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74663.1 - 5.7e-05 22.8 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG74663.1 - 0.017 15.5 0.8 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG74663.1 - 0.2 11.3 1.3 19 4.8 0.2 2.5 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG74664.1 - 6.8e-06 26.4 1.7 3.1e-05 24.3 0.5 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG74666.1 - 6.3e-26 90.3 0.0 1.1e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74666.1 - 3.5e-22 78.7 0.0 6.6e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74666.1 - 5.7e-11 42.4 0.1 9.3e-11 41.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG74666.1 - 2.1 6.5 11.5 2.7 6.1 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG74666.1 - 7.3 4.7 10.4 10 4.2 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Fasciclin PF02469.22 GBG74669.1 - 0.0074 16.5 0.3 0.012 15.8 0.2 1.3 1 1 0 1 1 1 1 Fasciclin domain Pheromone PF08015.11 GBG74670.1 - 1.3 10.1 4.8 1.2 10.2 0.3 3.6 2 0 0 2 2 2 0 Fungal mating-type pheromone Nop14 PF04147.12 GBG74671.1 - 0.43 8.7 27.3 0.6 8.2 27.3 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG74671.1 - 3.5 6.3 19.0 3.3 6.4 19.0 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GBG74671.1 - 7.4 5.7 9.7 9 5.4 9.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 GBG74671.1 - 8.4 6.3 15.1 12 5.9 15.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A GIY-YIG PF01541.24 GBG74672.1 - 4.2e-06 27.0 0.0 4.2e-06 27.0 0.0 2.8 2 1 1 3 3 3 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG74672.1 - 0.015 15.4 1.2 0.037 14.1 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG74673.1 - 1.2e-26 93.6 0.0 2e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG74673.1 - 0.019 15.6 0.0 0.061 14.0 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG74673.1 - 0.037 13.8 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DEK_C PF08766.11 GBG74674.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain Mito_carr PF00153.27 GBG74675.1 - 2.6e-54 181.1 7.5 1e-21 76.6 0.1 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Gly-zipper_YMGG PF13441.6 GBG74675.1 - 0.0001 22.0 5.8 0.078 12.7 0.0 3.7 3 1 0 3 3 3 2 YMGG-like Gly-zipper Ribosomal_60s PF00428.19 GBG74675.1 - 0.17 12.5 0.8 4.5 7.9 0.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein SR-25 PF10500.9 GBG74675.1 - 0.47 10.0 16.5 0.034 13.7 10.9 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 GBG74676.1 - 1.6e-29 103.1 0.1 2.8e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74676.1 - 1.1e-13 51.0 0.0 5.1e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG74676.1 - 1.5e-11 44.6 0.0 3.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain APH PF01636.23 GBG74676.1 - 5.1e-05 23.3 0.1 5.1e-05 23.3 0.1 2.3 3 0 0 3 3 2 1 Phosphotransferase enzyme family zf-H2C2 PF09337.10 GBG74676.1 - 0.0044 17.2 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger eIF-1a PF01176.19 GBG74676.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 RT_RNaseH PF17917.1 GBG74676.1 - 0.099 12.9 0.2 0.31 11.4 0.2 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG74676.1 - 0.11 12.3 0.0 0.39 10.5 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Tox-SHH PF15652.6 GBG74676.1 - 0.13 13.2 2.2 6.4 7.8 0.0 3.1 3 0 0 3 3 2 0 HNH/Endo VII superfamily toxin with a SHH signature bZIP_2 PF07716.15 GBG74676.1 - 0.16 12.1 3.8 0.64 10.2 3.8 2.1 1 0 0 1 1 1 0 Basic region leucine zipper DIT1_PvcA PF05141.12 GBG74676.1 - 0.17 11.3 0.0 0.46 9.9 0.0 1.7 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein RVT_1 PF00078.27 GBG74677.1 - 1.5e-29 103.1 0.1 2.6e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74677.1 - 1e-13 51.1 0.0 4.9e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG74677.1 - 1.4e-11 44.7 0.0 3.2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain APH PF01636.23 GBG74677.1 - 4.9e-05 23.4 0.1 4.9e-05 23.4 0.1 2.4 3 0 0 3 3 2 1 Phosphotransferase enzyme family zf-H2C2 PF09337.10 GBG74677.1 - 0.004 17.3 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger eIF-1a PF01176.19 GBG74677.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 RT_RNaseH PF17917.1 GBG74677.1 - 0.093 13.0 0.2 0.29 11.4 0.2 1.9 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG74677.1 - 0.1 12.4 0.0 0.37 10.6 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Tox-SHH PF15652.6 GBG74677.1 - 0.12 13.3 2.3 6.1 7.9 0.0 3.1 3 0 0 3 3 2 0 HNH/Endo VII superfamily toxin with a SHH signature bZIP_2 PF07716.15 GBG74677.1 - 0.15 12.2 3.8 0.6 10.2 3.8 2.1 1 0 0 1 1 1 0 Basic region leucine zipper DIT1_PvcA PF05141.12 GBG74677.1 - 0.16 11.4 0.0 0.44 10.0 0.0 1.7 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein HTH_55 PF18622.1 GBG74678.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 RctB helix turn helix domain DEK_C PF08766.11 GBG74678.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain SDA1 PF05285.12 GBG74679.1 - 1 8.7 16.2 1.4 8.3 16.2 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG74679.1 - 1.3 7.3 12.7 1.6 6.9 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C37 PF05416.12 GBG74679.1 - 6.6 5.1 6.6 9 4.7 6.6 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Nop14 PF04147.12 GBG74679.1 - 7.1 4.7 17.5 8.8 4.4 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG74681.1 - 9e-21 74.4 0.1 1.7e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_28 PF02636.17 GBG74681.1 - 7.8e-16 58.5 0.0 2.1e-10 40.7 0.0 3.6 3 1 0 3 3 3 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Asp_protease_2 PF13650.6 GBG74681.1 - 4.5e-07 30.4 0.0 1.5e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74681.1 - 3.7e-06 27.4 0.0 2.1e-05 25.0 0.0 2.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74681.1 - 3.7e-05 23.5 0.0 0.00013 21.7 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74681.1 - 0.0021 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF4407 PF14362.6 GBG74681.1 - 0.0063 15.9 5.8 0.027 13.9 4.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Retrotrans_gag PF03732.17 GBG74681.1 - 0.035 14.4 0.0 0.29 11.5 0.0 2.6 1 0 0 1 1 1 0 Retrotransposon gag protein Methyltransf_12 PF08242.12 GBG74681.1 - 0.075 13.8 0.0 0.34 11.7 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain UQ_con PF00179.26 GBG74683.1 - 1.6e-49 167.1 0.0 1.9e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GBG74683.1 - 0.00015 21.5 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GBG74683.1 - 0.02 14.7 0.1 0.039 13.8 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 GBG74683.1 - 0.085 13.1 0.2 0.12 12.7 0.2 1.6 1 1 0 1 1 1 0 RWD domain zf-CCHC PF00098.23 GBG74684.1 - 0.00095 19.1 3.7 0.0017 18.3 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4043 PF13252.6 GBG74684.1 - 0.0067 15.6 0.2 0.011 14.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4043) DUF3682 PF12446.8 GBG74684.1 - 0.0082 16.6 3.6 0.0082 16.6 3.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3682) DUF484 PF04340.12 GBG74684.1 - 0.018 14.7 0.1 0.018 14.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF484 zf-CCHC_2 PF13696.6 GBG74684.1 - 0.2 11.5 7.5 0.43 10.4 7.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Trimer_CC PF08954.11 GBG74684.1 - 0.48 10.0 11.8 0.5 10.0 1.2 4.8 6 0 0 6 6 6 0 Trimerisation motif DUF5339 PF17274.2 GBG74684.1 - 2.5 9.0 7.8 28 5.6 3.3 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5339) TolA_bind_tri PF16331.5 GBG74684.1 - 4.4 7.5 9.0 18 5.5 0.1 3.7 3 0 0 3 3 3 0 TolA binding protein trimerisation TMPIT PF07851.13 GBG74684.1 - 5.9 6.0 10.7 0.23 10.7 1.9 2.5 2 1 0 2 2 2 0 TMPIT-like protein FlaC_arch PF05377.11 GBG74684.1 - 6.5 7.2 13.1 29 5.1 0.1 4.3 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Abhydrolase_5 PF12695.7 GBG74685.1 - 1.7e-28 99.4 0.1 2.7e-20 72.8 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG74685.1 - 0.00022 20.9 0.1 0.00077 19.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG74685.1 - 0.011 15.0 0.2 0.043 13.1 0.0 2.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GBG74685.1 - 0.029 14.2 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase CCDC92 PF14916.6 GBG74686.1 - 0.13 12.0 19.6 0.68 9.7 0.1 5.1 5 1 0 5 5 5 0 Coiled-coil domain of unknown function DUF2481 PF10654.9 GBG74686.1 - 2.6 8.1 11.9 1.1 9.3 0.3 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2481) Abhydrolase_5 PF12695.7 GBG74687.1 - 1.4e-43 148.5 0.0 4.3e-20 72.1 0.0 3.3 3 0 0 3 3 3 2 Alpha/beta hydrolase family RVT_1 PF00078.27 GBG74687.1 - 5.3e-30 104.6 0.1 9.8e-30 103.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74687.1 - 1.7e-29 101.8 0.0 3.6e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74687.1 - 6.8e-29 100.2 0.0 1.3e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG74687.1 - 5.6e-07 29.9 1.2 1.4e-06 28.5 1.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Chlorophyllase PF07224.11 GBG74687.1 - 2.4e-06 26.8 0.6 0.037 13.0 0.1 2.3 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_1 PF00561.20 GBG74687.1 - 5.5e-06 26.2 0.1 0.049 13.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG74687.1 - 1.5e-05 24.4 0.0 0.45 9.7 0.0 3.7 4 0 0 4 4 4 2 Serine aminopeptidase, S33 TRAPPC10 PF12584.8 GBG74687.1 - 0.083 12.6 0.0 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 Pkinase PF00069.25 GBG74688.1 - 5.8e-55 186.5 0.0 7e-53 179.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG74688.1 - 5.3e-37 127.5 0.0 2.2e-36 125.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase dCMP_cyt_deam_1 PF00383.23 GBG74688.1 - 3.8e-21 74.9 0.0 7.1e-14 51.5 0.0 2.7 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GBG74688.1 - 1.2e-08 34.8 0.1 6.3e-06 26.0 0.1 2.7 2 0 0 2 2 2 2 MafB19-like deaminase Pkinase_fungal PF17667.1 GBG74688.1 - 0.00022 20.1 0.0 0.00053 18.9 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GBG74688.1 - 0.019 14.3 0.0 0.098 11.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 GBG74688.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop16 PF09420.10 GBG74689.1 - 5.8e-12 46.1 0.1 6.2e-12 46.0 0.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 RT_RNaseH_2 PF17919.1 GBG74690.1 - 4.3e-18 65.2 0.0 8.3e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74690.1 - 5.9e-18 65.1 0.0 1.3e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74690.1 - 8.7e-10 38.8 0.0 2.4e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG74690.1 - 5.7e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74691.1 - 2.6e-18 65.9 0.0 4.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74691.1 - 3.6e-18 65.8 0.0 7.4e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74691.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT PF02985.22 GBG74692.1 - 7.9e-06 25.7 5.5 3.5 8.1 0.1 6.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 GBG74692.1 - 9.9e-06 25.7 15.4 0.27 11.3 0.2 6.7 4 3 4 8 8 8 3 non-SMC mitotic condensation complex subunit 1 LBR_tudor PF09465.10 GBG74692.1 - 0.0017 18.2 0.7 0.0038 17.0 0.7 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain HEAT_2 PF13646.6 GBG74692.1 - 0.013 15.9 6.5 0.085 13.3 0.0 4.8 4 3 1 6 6 6 0 HEAT repeats MA3 PF02847.17 GBG74692.1 - 0.11 12.5 0.1 1.6 8.7 0.0 2.9 2 0 0 2 2 2 0 MA3 domain TAN PF11640.8 GBG74692.1 - 1.5 9.0 4.2 13 5.9 0.0 3.9 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair HEAT PF02985.22 GBG74693.1 - 7.6e-06 25.7 5.5 3.5 8.2 0.1 6.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 GBG74693.1 - 9.4e-06 25.8 15.4 0.27 11.3 0.2 6.7 4 3 4 8 8 8 3 non-SMC mitotic condensation complex subunit 1 LBR_tudor PF09465.10 GBG74693.1 - 0.0016 18.2 0.7 0.0037 17.0 0.7 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain HEAT_2 PF13646.6 GBG74693.1 - 0.014 15.8 6.6 0.084 13.3 0.0 4.8 4 3 1 6 6 6 0 HEAT repeats MA3 PF02847.17 GBG74693.1 - 0.1 12.5 0.1 1.6 8.7 0.0 2.9 2 0 0 2 2 2 0 MA3 domain TAN PF11640.8 GBG74693.1 - 1.1 9.3 3.8 12 6.0 0.0 3.9 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair CtsR PF05848.11 GBG74695.1 - 0.15 12.0 0.0 54 3.8 0.0 3.4 3 1 1 4 4 4 0 CtsR N-terminal HTH domain Glyco_transf_43 PF03360.16 GBG74696.1 - 4.1e-49 167.2 0.1 7.3e-49 166.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 43 GST_N_2 PF13409.6 GBG74697.1 - 5.1e-15 55.5 0.0 9.6e-15 54.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GBG74697.1 - 0.087 13.3 0.0 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain zf-CCHC PF00098.23 GBG74698.1 - 2.8e-05 24.0 4.4 4.5e-05 23.3 4.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG74698.1 - 0.0011 18.8 3.9 0.0016 18.2 3.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG74698.1 - 0.0043 17.0 1.5 0.0043 17.0 1.5 1.9 2 0 0 2 2 2 1 Zinc knuckle ASCH PF04266.14 GBG74698.1 - 0.05 14.2 0.3 0.14 12.7 0.0 1.9 1 1 1 2 2 2 0 ASCH domain Cytochrome_C554 PF13435.6 GBG74698.1 - 1.1 10.3 0.0 1.1 10.3 0.0 2.9 2 1 0 2 2 2 0 Cytochrome c554 and c-prime WDCP PF15390.6 GBG74698.1 - 1.3 7.3 5.8 1.6 7.1 5.8 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family UPF0242 PF06785.11 GBG74698.1 - 2 8.5 11.2 3 7.9 11.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CHD5 PF04420.14 GBG74698.1 - 3.9 7.3 7.7 6.9 6.5 7.7 1.4 1 0 0 1 1 1 0 CHD5-like protein PPR_2 PF13041.6 GBG74699.1 - 0.085 13.1 0.0 3.6 7.9 0.0 2.5 2 0 0 2 2 2 0 PPR repeat family Mito_carr PF00153.27 GBG74700.1 - 1.9e-43 146.3 2.9 2.1e-16 59.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 GBG74701.1 - 8.8e-41 137.8 2.4 4.8e-17 61.7 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GBG74701.1 - 0.15 11.2 0.0 25 3.9 0.0 3.3 4 0 0 4 4 4 0 Gammaproteobacterial serine protease Choline_kinase PF01633.20 GBG74702.1 - 1.5e-57 194.7 0.0 2.3e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GBG74702.1 - 7.7e-10 39.1 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF805 PF05656.14 GBG74702.1 - 0.022 15.2 0.1 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF805) EcKinase PF02958.20 GBG74702.1 - 0.16 11.3 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase CMS1 PF14617.6 GBG74704.1 - 6.6e-30 104.3 0.0 6.6e-30 104.3 0.0 2.8 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 GBG74704.1 - 1.9e-08 34.3 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PPP4R2 PF09184.11 GBG74704.1 - 0.051 13.2 4.8 0.069 12.7 4.8 1.1 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 GBG74704.1 - 2.4 8.3 14.1 4.2 7.6 14.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 GBG74704.1 - 3.4 5.9 7.6 2.7 6.2 6.3 1.5 2 0 0 2 2 2 0 CDC45-like protein AAA_2 PF07724.14 GBG74705.1 - 5.2e-58 195.9 0.4 3.2e-54 183.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GBG74705.1 - 6.9e-34 115.9 0.8 6.9e-34 115.9 0.8 3.0 1 1 2 3 3 2 1 AAA lid domain Clp_N PF02861.20 GBG74705.1 - 3.2e-29 100.8 0.2 4.1e-16 58.8 0.1 3.1 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component ClpB_D2-small PF10431.9 GBG74705.1 - 1.8e-26 92.0 3.4 2.7e-26 91.4 0.9 2.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GBG74705.1 - 1.8e-24 86.6 0.0 2e-12 47.7 0.0 3.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GBG74705.1 - 4.2e-19 68.9 0.3 7.5e-13 48.7 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG74705.1 - 1.4e-09 38.6 1.4 0.00014 22.3 0.0 4.3 3 2 1 5 5 3 2 AAA ATPase domain Sigma54_activat PF00158.26 GBG74705.1 - 1.5e-09 37.8 0.0 8.5e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 GBG74705.1 - 1.3e-07 31.5 0.0 0.011 15.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 GBG74705.1 - 3e-07 30.8 2.9 0.13 12.5 0.0 5.4 4 2 0 4 4 4 2 AAA domain AAA_14 PF13173.6 GBG74705.1 - 1.1e-05 25.4 0.0 0.32 11.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 GBG74705.1 - 1.5e-05 24.5 0.0 0.024 14.1 0.0 3.6 2 2 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 GBG74705.1 - 2.6e-05 24.1 0.0 0.028 14.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 GBG74705.1 - 3.3e-05 24.4 2.5 0.15 12.6 0.0 3.7 4 0 0 4 4 3 2 AAA domain RuvB_N PF05496.12 GBG74705.1 - 4e-05 23.4 0.3 2.4 7.9 0.0 4.1 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GBG74705.1 - 7.7e-05 23.0 0.0 0.72 10.3 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_7 PF12775.7 GBG74705.1 - 0.00013 21.5 0.0 0.15 11.6 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 GBG74705.1 - 0.00014 21.3 0.1 0.74 9.2 0.0 3.3 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GBG74705.1 - 0.0002 21.7 0.1 1.3 9.2 0.0 3.6 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 GBG74705.1 - 0.00026 20.3 0.0 0.088 12.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 GBG74705.1 - 0.00032 20.9 0.8 0.56 10.4 0.1 3.8 3 1 0 3 3 2 1 AAA domain NACHT PF05729.12 GBG74705.1 - 0.00065 19.7 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 GBG74705.1 - 0.00067 19.3 0.1 0.18 11.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 GBG74705.1 - 0.00078 19.7 0.1 4.7 7.5 0.0 3.7 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GBG74705.1 - 0.0012 18.8 0.0 1.3 8.9 0.0 3.2 2 1 0 2 2 2 1 RsgA GTPase ResIII PF04851.15 GBG74705.1 - 0.0013 18.7 1.4 0.22 11.5 0.0 4.0 4 1 1 5 5 3 1 Type III restriction enzyme, res subunit TsaE PF02367.17 GBG74705.1 - 0.0022 18.0 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GBG74705.1 - 0.0043 17.6 0.2 1.4 9.4 0.0 3.5 3 0 0 3 3 3 1 ABC transporter DNA_pol3_delta2 PF13177.6 GBG74705.1 - 0.0064 16.3 0.0 0.79 9.5 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 GBG74705.1 - 0.0071 16.2 0.2 2.3 8.1 0.1 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 GBG74705.1 - 0.0095 15.9 4.6 8.2 6.3 0.0 4.1 4 1 0 4 4 4 0 ATPase domain predominantly from Archaea PhoH PF02562.16 GBG74705.1 - 0.013 14.9 0.0 2.9 7.3 0.0 2.8 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 GBG74705.1 - 0.035 13.7 0.0 0.87 9.2 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Snapin_Pallidin PF14712.6 GBG74705.1 - 0.042 14.3 15.2 0.36 11.3 4.2 4.0 3 1 0 4 4 3 0 Snapin/Pallidin TIP49 PF06068.13 GBG74705.1 - 0.049 12.8 8.1 3.4 6.8 0.0 3.5 3 1 1 4 4 4 0 TIP49 P-loop domain AAA_23 PF13476.6 GBG74705.1 - 0.078 13.5 0.0 0.078 13.5 0.0 4.2 3 1 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 GBG74705.1 - 0.086 12.6 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 GBG74705.1 - 0.15 12.0 0.8 30 4.5 0.0 3.7 4 0 0 4 4 3 0 NTPase DUF4407 PF14362.6 GBG74705.1 - 1.2 8.4 8.9 3.3 7.0 8.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RT_RNaseH_2 PF17919.1 GBG74706.1 - 1.2e-25 89.4 0.0 1.9e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74706.1 - 5e-24 84.6 0.0 8.1e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG74706.1 - 0.038 12.2 7.0 0.047 11.9 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG74706.1 - 0.39 10.1 10.9 0.53 9.6 10.9 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG74706.1 - 0.43 8.8 10.8 0.55 8.4 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TauE PF01925.19 GBG74707.1 - 1.1e-20 74.3 18.3 8.9e-14 51.7 9.6 3.3 3 0 0 3 3 3 3 Sulfite exporter TauE/SafE RT_RNaseH_2 PF17919.1 GBG74708.1 - 1.4e-32 111.7 0.1 3.6e-32 110.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74708.1 - 2.1e-31 109.2 0.1 3.5e-31 108.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74708.1 - 2.1e-28 98.6 0.2 6.4e-28 97.1 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74708.1 - 8.5e-18 64.2 0.2 2.1e-17 63.0 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74708.1 - 2.9e-09 37.2 0.1 1.8e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Apc13p PF05839.11 GBG74708.1 - 0.078 13.2 0.3 0.23 11.6 0.3 1.8 1 0 0 1 1 1 0 Apc13p protein zf-H2C2 PF09337.10 GBG74708.1 - 0.097 12.9 0.2 0.96 9.7 0.1 2.6 2 0 0 2 2 2 0 H2C2 zinc finger IceA2 PF05862.11 GBG74708.1 - 0.18 11.7 0.3 0.36 10.8 0.3 1.5 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein TauE PF01925.19 GBG74709.1 - 2.2e-25 89.7 16.8 2.3e-13 50.4 5.0 2.3 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE rve PF00665.26 GBG74710.1 - 1.2e-09 38.4 0.0 2.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG74710.1 - 0.00043 20.1 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG74710.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG74711.1 - 2.5e-28 99.1 0.1 3.8e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74711.1 - 3.2e-24 85.2 0.0 5.9e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74711.1 - 3.2e-22 78.4 0.0 7.5e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG74711.1 - 1.1e-07 31.7 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74711.1 - 5.4e-06 27.0 0.0 1.7e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74711.1 - 0.0002 21.8 0.0 0.00052 20.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG74711.1 - 0.0036 17.1 0.0 0.0085 15.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG74711.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Chloroa_b-bind PF00504.21 GBG74713.1 - 4.7e-50 170.3 0.5 6.1e-50 169.9 0.1 1.4 2 0 0 2 2 2 1 Chlorophyll A-B binding protein Kinesin PF00225.23 GBG74715.1 - 2.8e-248 822.0 50.4 8.6e-69 232.0 2.8 10.1 7 3 3 10 10 10 10 Kinesin motor domain Microtub_bd PF16796.5 GBG74715.1 - 5.3e-52 175.7 5.9 2.4e-16 60.0 0.0 4.5 4 0 0 4 4 4 4 Microtubule binding ATPase_2 PF01637.18 GBG74715.1 - 3.6e-05 23.8 0.2 3.1 7.7 0.0 4.2 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea DUF3717 PF12512.8 GBG74715.1 - 4.6e-05 23.2 0.0 0.95 9.4 0.0 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3717) DUF3426 PF11906.8 GBG74715.1 - 0.00027 21.1 1.2 6.7 6.9 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3426) Katanin_con80 PF13925.6 GBG74715.1 - 0.01 15.9 3.3 6.2 6.8 0.1 4.7 4 0 0 4 4 4 0 con80 domain of Katanin DUF5062 PF16691.5 GBG74715.1 - 0.029 14.5 0.4 3 8.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5062) DUF2015 PF09435.10 GBG74715.1 - 0.048 13.5 0.0 28 4.6 0.0 3.5 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF2015) DUF2189 PF09955.9 GBG74715.1 - 0.25 11.6 0.3 1.1e+02 3.0 0.0 4.0 4 0 0 4 4 4 0 Predicted integral membrane protein (DUF2189) Hormone_1 PF00103.20 GBG74715.1 - 0.25 11.1 4.6 41 3.8 0.1 4.6 4 0 0 4 4 4 0 Somatotropin hormone family CHCH PF06747.13 GBG74715.1 - 0.69 10.1 6.3 82 3.5 0.0 4.7 5 0 0 5 5 5 0 CHCH domain Pro_3_hydrox_C PF05373.11 GBG74715.1 - 0.75 9.9 3.6 48 4.1 0.1 3.5 3 0 0 3 3 3 0 L-proline 3-hydroxylase, C-terminal Drf_GBD PF06371.13 GBG74715.1 - 1 8.9 8.3 2.5 7.6 0.1 3.8 4 0 0 4 4 4 0 Diaphanous GTPase-binding Domain Kinesin PF00225.23 GBG74716.1 - 4e-131 436.9 17.3 2.2e-57 194.5 4.6 4.1 3 1 1 4 4 4 4 Kinesin motor domain DUF3426 PF11906.8 GBG74716.1 - 1.9e-05 24.8 0.2 0.13 12.4 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3426) GST_N_4 PF17172.4 GBG74716.1 - 0.085 13.6 0.1 14 6.5 0.0 3.0 3 0 0 3 3 3 0 Glutathione S-transferase N-terminal domain Bcl-2_3 PF15286.6 GBG74717.1 - 0.034 14.8 0.8 0.039 14.6 0.8 1.0 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like EI24 PF07264.11 GBG74719.1 - 3.5e-30 105.6 4.7 4.2e-30 105.3 4.7 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) cIII PF08134.11 GBG74719.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 cIII protein family DUF4720 PF15846.5 GBG74719.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) Chloroa_b-bind PF00504.21 GBG74720.1 - 2.5e-50 171.2 0.5 3.4e-50 170.7 0.0 1.4 2 0 0 2 2 2 1 Chlorophyll A-B binding protein SAPS PF04499.15 GBG74722.1 - 2.8 6.6 12.3 3.2 6.5 12.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG74722.1 - 4.7 5.3 26.8 5.3 5.1 26.8 1.0 1 0 0 1 1 1 0 Nop14-like family Chloroa_b-bind PF00504.21 GBG74723.1 - 1.9e-29 103.3 0.0 2.3e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GBG74724.1 - 2.5e-50 171.2 0.5 3.4e-50 170.7 0.0 1.4 2 0 0 2 2 2 1 Chlorophyll A-B binding protein Retrotrans_gag PF03732.17 GBG74725.1 - 0.1 12.9 1.8 0.78 10.1 0.0 2.9 2 1 0 2 2 2 0 Retrotransposon gag protein DUF5401 PF17380.2 GBG74725.1 - 4.1 5.4 42.2 6.3 4.7 42.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Chloroa_b-bind PF00504.21 GBG74726.1 - 2.2e-50 171.3 0.3 3.4e-50 170.7 0.0 1.4 2 0 0 2 2 2 1 Chlorophyll A-B binding protein zf-CCHC PF00098.23 GBG74727.1 - 2.1e-08 33.8 2.4 5.2e-08 32.6 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG74727.1 - 0.00094 19.7 0.0 0.0035 17.9 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Nitr_red_alph_N PF14710.6 GBG74727.1 - 0.028 14.9 0.1 0.86 10.1 0.0 2.5 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal Asp_protease_2 PF13650.6 GBG74727.1 - 0.046 14.4 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG74727.1 - 0.048 13.5 2.6 0.089 12.6 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG74727.1 - 3.6 7.6 5.7 0.42 10.6 0.4 2.2 3 0 0 3 3 3 0 Zinc knuckle MSA-2c PF12238.8 GBG74727.1 - 4.9 7.1 6.3 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c RT_RNaseH_2 PF17919.1 GBG74728.1 - 1.4e-28 98.8 0.0 2.6e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74728.1 - 7.6e-26 90.4 0.0 1.6e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74728.1 - 1.7e-15 57.1 0.0 2.6e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C48 PF02902.19 GBG74729.1 - 9.5e-10 38.7 0.0 2.4e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RT_RNaseH_2 PF17919.1 GBG74730.1 - 7e-16 58.1 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG74730.1 - 4.5e-10 39.4 0.0 2e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG74730.1 - 1e-08 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74730.1 - 9.7e-07 29.0 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG74730.1 - 0.0002 21.3 1.3 0.00042 20.3 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Neur_chan_memb PF02932.16 GBG74730.1 - 0.083 12.9 0.8 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Plant_tran PF04827.14 GBG74730.1 - 0.17 11.4 0.0 0.49 10.0 0.0 1.7 2 0 0 2 2 2 0 Plant transposon protein SDA1 PF05285.12 GBG74730.1 - 0.25 10.7 10.9 0.41 10.0 10.9 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG74730.1 - 0.87 7.8 8.7 1.3 7.2 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG74731.1 - 2.8e-24 85.0 0.0 5.3e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74731.1 - 1.3e-14 54.3 0.0 2.8e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG74731.1 - 2.4e-10 40.3 0.0 1.3e-09 37.9 0.0 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG74731.1 - 6.7e-09 35.6 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG74731.1 - 0.00013 21.9 1.3 0.0003 20.7 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Plant_tran PF04827.14 GBG74731.1 - 0.098 12.2 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Plant transposon protein Chloroa_b-bind PF00504.21 GBG74733.1 - 4.1e-50 170.5 0.4 5.7e-50 170.0 0.0 1.4 2 0 0 2 2 2 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GBG74734.1 - 2.2e-50 171.4 0.5 2.9e-50 170.9 0.1 1.4 2 0 0 2 2 2 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GBG74735.1 - 1.9e-50 171.5 0.1 2.8e-50 171.0 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein NAD_binding_9 PF13454.6 GBG74736.1 - 0.0016 18.4 2.1 0.006 16.6 0.4 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding PRIMA1 PF16101.5 GBG74736.1 - 1 9.4 5.2 2.9 8.0 5.2 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG74736.1 - 3 7.3 6.7 5.9 6.3 6.7 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RVT_1 PF00078.27 GBG74737.1 - 6.8e-15 55.2 0.0 3.9e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG74738.1 - 0.00031 20.7 6.2 0.00071 19.5 6.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG74738.1 - 0.67 9.8 8.6 1.2 9.0 5.3 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF4407 PF14362.6 GBG74738.1 - 4.1 6.7 7.7 7.1 5.9 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Menin PF05053.13 GBG74738.1 - 6 5.1 10.1 7.9 4.7 10.1 1.1 1 0 0 1 1 1 0 Menin Zeta_toxin PF06414.12 GBG74739.1 - 0.00013 21.3 0.1 0.0002 20.7 0.1 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 GBG74739.1 - 0.00022 21.8 0.0 0.0015 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 GBG74739.1 - 0.0034 16.4 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 GBG74739.1 - 0.0045 17.5 0.0 0.0076 16.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GBG74739.1 - 0.0056 17.1 0.0 0.0095 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 GBG74739.1 - 0.0074 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 GBG74739.1 - 0.0094 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 GBG74739.1 - 0.013 15.9 0.1 0.022 15.2 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG74739.1 - 0.024 14.9 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GBG74739.1 - 0.025 14.8 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GBG74739.1 - 0.032 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 GBG74739.1 - 0.04 13.9 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 GBG74739.1 - 0.051 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 GBG74739.1 - 0.069 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 GBG74739.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 GBG74739.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 GBG74739.1 - 0.16 12.4 0.4 0.43 11.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 GBG74739.1 - 0.16 12.2 0.1 0.43 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GBG74739.1 - 0.22 11.4 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 NTPase tRNA_synt_2f PF02092.17 GBG74740.1 - 5.4e-176 586.6 0.0 6.9e-176 586.3 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit tRNA-synt_2e PF02091.15 GBG74740.1 - 3.4e-136 453.0 0.0 6.2e-136 452.1 0.0 1.4 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit DALR_1 PF05746.15 GBG74740.1 - 0.00063 19.9 0.0 0.0025 18.0 0.0 2.1 1 0 0 1 1 1 1 DALR anticodon binding domain HTH_32 PF13565.6 GBG74740.1 - 0.17 12.5 0.5 11 6.7 0.1 3.0 2 0 0 2 2 2 0 Homeodomain-like domain RVT_1 PF00078.27 GBG74741.1 - 5.6e-35 120.9 0.1 9.9e-35 120.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74741.1 - 8e-31 106.0 0.1 2.6e-30 104.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74741.1 - 2.2e-30 105.0 0.3 8.3e-30 103.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74741.1 - 1.2e-19 70.2 0.6 2.5e-19 69.1 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74741.1 - 5.3e-17 62.1 0.0 1.3e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74741.1 - 0.00056 20.1 0.1 0.0021 18.2 0.1 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG74741.1 - 0.075 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Latarcin PF10279.9 GBG74741.1 - 0.088 13.2 0.2 0.36 11.2 0.1 2.1 2 0 0 2 2 2 0 Latarcin precursor FAM60A PF15396.6 GBG74742.1 - 5.4 7.0 13.1 11 5.9 13.1 1.6 1 1 0 1 1 1 0 Protein Family FAM60A Ras PF00071.22 GBG74743.1 - 1.3e-55 187.4 0.8 1.6e-55 187.1 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG74743.1 - 5.9e-26 91.1 0.4 1.1e-25 90.2 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG74743.1 - 2.7e-14 53.0 0.2 3.1e-14 52.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GBG74743.1 - 2.4e-05 24.0 0.3 4.8e-05 23.0 0.2 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain LANC_like PF05147.13 GBG74743.1 - 0.018 13.7 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein DUF3873 PF12989.7 GBG74743.1 - 0.044 14.2 0.1 0.079 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) Gtr1_RagA PF04670.12 GBG74743.1 - 0.048 13.0 0.1 0.056 12.8 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dioxygenase_N PF04444.14 GBG74743.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Gb3_synth PF04572.12 GBG74744.1 - 1.2e-24 87.0 0.1 2.7e-24 85.8 0.1 1.6 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 GBG74744.1 - 7.1e-20 71.5 0.0 1.2e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 GBG74744.1 - 0.056 12.7 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain RT_RNaseH PF17917.1 GBG74746.1 - 8.3e-27 93.5 0.4 2.9e-26 91.8 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74746.1 - 4.3e-26 90.9 0.0 1.5e-25 89.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74746.1 - 0.073 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Mcl1_mid PF12341.8 GBG74747.1 - 2.2e-79 266.9 0.0 5.2e-79 265.7 0.0 1.7 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 GBG74747.1 - 4.8e-24 84.2 21.4 0.00011 23.0 0.3 7.8 8 0 0 8 8 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG74747.1 - 1.4e-19 70.2 0.0 0.00064 20.0 0.0 6.9 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG74747.1 - 0.00022 21.2 0.0 0.6 9.9 0.0 3.5 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GBG74747.1 - 0.022 13.7 0.0 1.2 8.1 0.0 3.3 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GBG74747.1 - 0.059 13.3 0.1 8.9 6.4 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 GBG74747.1 - 0.062 12.6 0.0 0.25 10.7 0.0 1.9 2 1 0 2 2 2 0 WD40-like domain Nop14 PF04147.12 GBG74747.1 - 2 6.5 32.6 2.8 6.0 32.6 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG74747.1 - 3 7.1 33.8 4.2 6.6 33.8 1.1 1 0 0 1 1 1 0 BUD22 Merozoite_SPAM PF07133.11 GBG74747.1 - 6.4 6.7 41.5 13 5.7 41.5 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 GBG74747.1 - 6.5 4.9 27.5 9.7 4.3 27.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 GBG74747.1 - 7.1 5.5 25.4 12 4.8 25.4 1.3 1 0 0 1 1 1 0 Paf1 MDM1 PF15501.6 GBG74747.1 - 8.9 5.3 21.8 13 4.8 21.8 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Mcl1_mid PF12341.8 GBG74748.1 - 2.5e-26 92.7 0.0 8.8e-26 90.9 0.0 1.9 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 GBG74748.1 - 2.3e-25 88.4 21.0 7e-05 23.5 0.3 7.7 8 0 0 8 8 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG74748.1 - 1.3e-20 73.4 0.0 0.00039 20.7 0.0 6.8 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG74748.1 - 5e-05 23.3 0.0 0.88 9.4 0.0 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GBG74748.1 - 0.0066 15.4 0.0 0.76 8.7 0.0 3.5 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GBG74748.1 - 0.017 15.1 0.1 6.1 6.9 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 GBG74748.1 - 0.032 13.6 0.0 0.16 11.3 0.0 2.0 2 1 1 3 3 3 0 WD40-like domain Frtz PF11768.8 GBG74748.1 - 0.13 10.6 0.0 1.3 7.3 0.0 2.3 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nop14 PF04147.12 GBG74748.1 - 1.2 7.2 32.6 1.7 6.8 32.6 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG74748.1 - 1.8 7.8 33.9 2.5 7.4 33.9 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG74748.1 - 4 5.6 27.6 5.9 5.1 27.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 GBG74748.1 - 5 7.1 41.5 8 6.4 41.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Paf1 PF03985.13 GBG74748.1 - 5.5 5.9 25.7 8.8 5.2 25.7 1.3 1 0 0 1 1 1 0 Paf1 PTPRCAP PF15713.5 GBG74748.1 - 7.1 6.9 26.8 14 5.9 26.8 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated MDM1 PF15501.6 GBG74748.1 - 7.4 5.6 22.3 10 5.1 22.3 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Jnk-SapK_ap_N PF09744.9 GBG74750.1 - 0.02 15.1 1.6 0.02 15.1 1.6 2.1 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 GBG74750.1 - 0.44 10.6 4.9 1.4 9.0 4.9 1.8 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Retrotrans_gag PF03732.17 GBG74751.1 - 0.00037 20.7 0.0 0.0015 18.8 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein SlyX PF04102.12 GBG74751.1 - 0.069 13.8 0.6 0.069 13.8 0.6 3.9 4 0 0 4 4 4 0 SlyX WTX PF09422.10 GBG74751.1 - 0.16 11.0 5.8 0.032 13.3 2.3 1.5 2 0 0 2 2 2 0 WTX protein DUF2722 PF10846.8 GBG74752.1 - 0.12 11.3 8.4 0.15 11.0 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BUD22 PF09073.10 GBG74752.1 - 7.9 5.7 31.2 30 3.8 31.2 1.7 1 1 0 1 1 1 0 BUD22 BUD22 PF09073.10 GBG74753.1 - 0.00011 21.7 18.8 0.00021 20.8 18.8 1.6 1 1 0 1 1 1 1 BUD22 DNA_pol_phi PF04931.13 GBG74754.1 - 0.085 10.9 3.3 0.13 10.3 3.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG74754.1 - 0.15 10.4 11.3 0.22 9.8 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SurE PF01975.17 GBG74754.1 - 0.2 11.4 2.0 0.46 10.2 2.0 1.6 1 0 0 1 1 1 0 Survival protein SurE ORC3_N PF07034.11 GBG74754.1 - 0.67 9.0 2.5 1 8.4 2.5 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus TFB6 PF17110.5 GBG74754.1 - 1.3 8.7 3.6 2.7 7.7 3.6 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SPATIAL PF15256.6 GBG74754.1 - 2.5 8.4 5.3 1.3 9.3 3.0 1.6 1 1 0 1 1 1 0 SPATIAL AF-4 PF05110.13 GBG74755.1 - 0.073 11.2 9.9 0.098 10.7 9.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RVT_1 PF00078.27 GBG74756.1 - 0.0023 17.5 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Thioredoxin_9 PF14595.6 GBG74757.1 - 4.4 7.1 6.0 7.7 6.3 1.9 2.6 2 0 0 2 2 2 0 Thioredoxin NAD_binding_1 PF00175.21 GBG74758.1 - 2.2e-27 95.8 0.0 3.8e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GBG74758.1 - 0.0032 17.8 0.0 0.0086 16.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.11 GBG74758.1 - 0.029 14.6 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain FAD_binding_1 PF00667.20 GBG74758.1 - 0.086 12.4 0.0 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain MULE PF10551.9 GBG74759.1 - 6.2e-17 61.8 0.0 3e-16 59.6 0.0 2.2 3 0 0 3 3 3 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG74759.1 - 1.7e-13 50.4 0.0 3.7e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase SWIM PF04434.17 GBG74759.1 - 3.4e-07 29.8 0.9 7.5e-07 28.7 0.1 2.0 2 0 0 2 2 2 1 SWIM zinc finger Transposase_mut PF00872.18 GBG74759.1 - 0.009 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family FhuF PF06276.12 GBG74759.1 - 0.071 13.5 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter AT_hook PF02178.19 GBG74759.1 - 1.5 9.0 17.6 3.9 7.7 8.1 3.0 2 0 0 2 2 2 0 AT hook motif SNF2_N PF00176.23 GBG74761.1 - 1.3e-68 231.3 1.8 2.2e-68 230.5 1.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG74761.1 - 8.7e-19 67.9 0.0 1.9e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG74761.1 - 5.5e-10 39.5 0.0 1.4e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG74761.1 - 7e-07 29.2 0.0 2.2e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-bind_6 PF13921.6 GBG74761.1 - 5.5e-05 23.3 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 GBG74761.1 - 0.00018 21.8 2.4 0.00018 21.8 2.4 3.4 3 0 0 3 3 3 1 HSA Nop14 PF04147.12 GBG74761.1 - 0.00044 18.6 26.1 0.00044 18.6 26.1 6.4 6 1 0 6 6 6 1 Nop14-like family Myb_DNA-binding PF00249.31 GBG74761.1 - 0.0026 17.9 0.0 0.0091 16.2 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain SNF2_N PF00176.23 GBG74762.1 - 1.3e-68 231.3 1.8 2.2e-68 230.5 1.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG74762.1 - 8.7e-19 67.9 0.0 1.9e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG74762.1 - 5.5e-10 39.5 0.0 1.4e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG74762.1 - 7e-07 29.2 0.0 2.2e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-bind_6 PF13921.6 GBG74762.1 - 5.5e-05 23.3 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 GBG74762.1 - 0.00018 21.8 2.4 0.00018 21.8 2.4 3.4 3 0 0 3 3 3 1 HSA Nop14 PF04147.12 GBG74762.1 - 0.00044 18.6 26.1 0.00044 18.6 26.1 6.3 6 1 0 6 6 6 1 Nop14-like family Myb_DNA-binding PF00249.31 GBG74762.1 - 0.0026 17.9 0.0 0.0091 16.2 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ion_trans PF00520.31 GBG74766.1 - 1e-36 126.4 16.3 1.5e-36 125.9 16.3 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 GBG74766.1 - 5.5e-05 22.0 11.7 0.00018 20.3 5.7 2.1 1 1 1 2 2 2 2 Polycystin cation channel Nop14 PF04147.12 GBG74766.1 - 0.0065 14.8 16.2 0.012 13.9 16.2 1.4 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 GBG74766.1 - 0.035 12.5 16.3 0.075 11.5 16.3 1.4 1 0 0 1 1 1 0 Mpp10 protein US6 PF17616.2 GBG74766.1 - 0.11 12.5 0.2 2.1 8.3 0.3 2.6 3 0 0 3 3 3 0 Viral unique short region 6 CDC45 PF02724.14 GBG74766.1 - 0.16 10.2 17.9 0.088 11.1 15.7 1.6 2 0 0 2 2 2 0 CDC45-like protein Myc_N PF01056.18 GBG74766.1 - 0.43 10.4 7.9 0.82 9.5 7.9 1.5 1 0 0 1 1 1 0 Myc amino-terminal region PPP4R2 PF09184.11 GBG74766.1 - 1.6 8.2 18.0 3.5 7.1 18.0 1.5 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 GBG74766.1 - 4.6 6.6 25.0 0.007 15.8 14.5 1.7 2 0 0 2 2 2 0 SDA1 gag-asp_proteas PF13975.6 GBG74768.1 - 1.7e-07 31.7 0.1 5.2e-07 30.1 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74768.1 - 0.00042 20.9 0.1 0.0011 19.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG74768.1 - 0.063 13.4 1.9 0.15 12.2 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG74769.1 - 2e-09 37.7 0.4 4.2e-09 36.7 0.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG74769.1 - 0.081 13.3 0.2 0.24 11.7 0.2 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG74769.1 - 0.17 12.0 0.7 0.44 10.6 0.7 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG74770.1 - 1e-11 44.7 0.0 1.4e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74770.1 - 0.013 15.2 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein CPSase_L_D2 PF02786.17 GBG74772.1 - 1.7e-72 243.3 0.0 2.4e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GBG74772.1 - 4.7e-45 152.6 0.0 3.5e-44 149.9 0.1 2.2 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GBG74772.1 - 2.9e-24 85.2 0.0 2e-14 53.6 0.0 2.5 1 1 1 2 2 2 2 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 GBG74772.1 - 1.5e-13 51.2 0.0 3.5e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 GBG74772.1 - 2.3e-06 27.3 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 GBG74772.1 - 0.015 15.3 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 GBG74772.1 - 0.029 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp LysM PF01476.20 GBG74773.1 - 3.7e-06 26.9 0.0 8.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 LysM domain SPRY PF00622.28 GBG74774.1 - 4.4e-12 46.2 2.8 8.3e-09 35.6 0.4 2.6 2 0 0 2 2 2 2 SPRY domain DDE_Tnp_4 PF13359.6 GBG74776.1 - 2.5e-21 76.0 0.0 3.3e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74776.1 - 3.9e-12 46.2 0.0 3.7e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG74776.1 - 0.0012 18.5 0.3 0.13 11.9 0.0 2.5 2 1 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG74777.1 - 8.5e-14 51.7 2.6 1.8e-13 50.7 2.6 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG74777.1 - 0.0019 18.3 0.8 0.0046 17.1 0.8 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG74777.1 - 0.046 14.0 0.5 0.046 14.0 0.5 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 GBG74777.1 - 0.22 12.5 1.2 0.42 11.6 1.2 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ENTH PF01417.20 GBG74780.1 - 6e-44 149.1 0.0 8e-44 148.7 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GBG74780.1 - 0.0023 17.0 0.1 0.0031 16.6 0.1 1.1 1 0 0 1 1 1 1 ANTH domain RVT_1 PF00078.27 GBG74781.1 - 1.8e-24 86.5 0.1 3.2e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74781.1 - 1.8e-16 60.0 0.0 5.5e-16 58.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74781.1 - 2.7e-15 56.2 2.1 5.1e-15 55.3 0.8 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG74781.1 - 8e-09 35.7 0.0 2e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG74781.1 - 1.1e-08 35.3 0.0 3.8e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG74781.1 - 0.0041 17.4 0.1 0.017 15.4 0.1 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG74781.1 - 0.092 13.0 0.4 0.25 11.6 0.4 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Caudo_TAP PF02413.17 GBG74781.1 - 0.19 11.9 10.2 2.8 8.1 2.0 2.6 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK TFIIA PF03153.13 GBG74781.1 - 0.98 9.4 7.4 2.1 8.2 7.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SMYLE_N PF18615.1 GBG74781.1 - 4.8 6.6 6.6 8 5.9 6.6 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Integrase_H2C2 PF17921.1 GBG74783.1 - 9.2e-19 67.3 0.2 2.2e-18 66.1 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG74783.1 - 6.6e-15 55.2 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG74783.1 - 0.00059 20.0 0.2 0.84 9.8 0.0 2.7 1 1 1 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG74783.1 - 0.18 12.1 0.0 0.51 10.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger NT-C2 PF10358.9 GBG74784.1 - 7e-13 48.5 0.0 1.3e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins LysM PF01476.20 GBG74784.1 - 3e-07 30.4 0.0 6.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 LysM domain YihI PF04220.12 GBG74784.1 - 0.0047 16.7 1.1 0.024 14.4 1.1 2.2 1 0 0 1 1 1 1 Der GTPase activator (YihI) RVT_1 PF00078.27 GBG74785.1 - 0.00019 21.0 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MAP7 PF05672.11 GBG74785.1 - 0.087 12.5 31.8 0.17 11.6 31.8 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF4637 PF15470.6 GBG74785.1 - 2 8.1 11.2 3.6 7.3 11.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2408 PF10303.9 GBG74787.1 - 3.8e-32 111.7 0.0 1.2e-10 42.1 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF2408) DUF948 PF06103.11 GBG74787.1 - 5.4e-05 23.4 0.7 0.14 12.4 0.0 3.0 3 0 0 3 3 2 2 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 GBG74787.1 - 8.8e-05 22.5 3.4 0.65 10.1 0.1 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) T3SS_needle_E PF08988.10 GBG74787.1 - 0.00062 19.9 2.6 0.083 13.1 0.2 3.6 3 1 1 4 4 3 1 Type III secretion system, cytoplasmic E component of needle BLOC1_2 PF10046.9 GBG74787.1 - 0.00092 19.5 7.0 0.053 13.8 0.4 3.1 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 GBG74787.1 - 0.0022 16.9 1.6 0.01 14.8 1.0 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF3450 PF11932.8 GBG74787.1 - 0.0044 16.4 3.2 0.016 14.5 0.2 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) CK2S PF15011.6 GBG74787.1 - 0.0055 16.6 1.1 0.53 10.1 0.1 2.6 3 0 0 3 3 2 1 Casein Kinase 2 substrate CENP-F_leu_zip PF10473.9 GBG74787.1 - 0.0084 16.1 4.0 0.98 9.4 1.5 2.4 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SesA PF17107.5 GBG74787.1 - 0.018 15.2 0.1 2.2 8.5 0.1 2.6 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF148 PF02520.17 GBG74787.1 - 0.028 14.5 1.0 7.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 Sec34 PF04136.15 GBG74787.1 - 0.038 13.9 3.8 3.9 7.4 0.1 2.7 3 0 0 3 3 2 0 Sec34-like family Laminin_II PF06009.12 GBG74787.1 - 0.048 13.7 1.0 2.5 8.1 0.2 2.5 2 0 0 2 2 2 0 Laminin Domain II Syntaxin PF00804.25 GBG74787.1 - 0.053 13.2 1.8 5.9 6.5 0.2 2.3 2 0 0 2 2 2 0 Syntaxin V_ATPase_I PF01496.19 GBG74787.1 - 0.058 11.3 0.9 0.081 10.8 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.11 GBG74787.1 - 0.069 13.2 3.7 3.7 7.6 0.1 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 WXG100 PF06013.12 GBG74787.1 - 0.071 13.3 0.5 10 6.5 0.0 3.5 3 0 0 3 3 2 0 Proteins of 100 residues with WXG KxDL PF10241.9 GBG74787.1 - 0.074 13.3 1.4 7.5 6.9 0.1 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF4559 PF15112.6 GBG74787.1 - 0.075 12.7 0.9 0.13 12.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Med4 PF10018.9 GBG74787.1 - 0.081 12.6 3.8 0.57 9.8 0.8 2.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 LXG PF04740.12 GBG74787.1 - 0.084 12.6 1.4 4.7 6.9 0.2 2.5 2 1 0 2 2 2 0 LXG domain of WXG superfamily eIF3_N PF09440.10 GBG74787.1 - 0.09 13.2 2.2 7.1 7.1 0.5 2.4 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Seryl_tRNA_N PF02403.22 GBG74787.1 - 0.092 13.0 1.5 2.6 8.3 0.2 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.6 GBG74787.1 - 0.097 12.7 6.7 1.5 8.9 0.7 2.7 3 0 0 3 3 2 0 FlxA-like protein DHR10 PF18595.1 GBG74787.1 - 0.1 12.7 4.0 2.1 8.4 1.0 3.1 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain TssO PF17561.2 GBG74787.1 - 0.11 12.6 2.8 3.9 7.6 0.0 2.8 4 0 0 4 4 2 0 Type VI secretion system, TssO Fungal_trans_2 PF11951.8 GBG74787.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain ACP_PD PF04336.12 GBG74787.1 - 0.14 12.6 1.4 26 5.3 0.1 3.4 2 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase DUF1759 PF03564.15 GBG74787.1 - 0.17 11.8 0.8 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Occludin_ELL PF07303.13 GBG74787.1 - 0.18 12.5 6.0 2.3 9.0 0.5 2.8 3 0 0 3 3 2 0 Occludin homology domain NCD2 PF04905.13 GBG74787.1 - 0.2 11.6 3.4 0.8 9.7 0.0 2.8 3 0 0 3 3 3 0 NAB conserved region 2 (NCD2) IFT57 PF10498.9 GBG74787.1 - 0.2 10.6 4.1 2 7.3 2.7 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 YabA PF06156.13 GBG74787.1 - 0.22 12.2 4.1 5.7 7.6 0.5 3.0 3 0 0 3 3 2 0 Initiation control protein YabA Rab5-bind PF09311.11 GBG74787.1 - 0.25 10.7 4.4 5.7 6.2 1.1 2.7 1 1 2 3 3 3 0 Rabaptin-like protein Syntaxin-6_N PF09177.11 GBG74787.1 - 0.27 11.8 1.9 5.2 7.7 1.3 2.6 2 1 0 2 2 1 0 Syntaxin 6, N-terminal Noelin-1 PF12308.8 GBG74787.1 - 0.28 11.2 1.9 1.8 8.6 0.0 2.6 3 0 0 3 3 2 0 Neurogenesis glycoprotein AAA_13 PF13166.6 GBG74787.1 - 0.33 9.5 2.7 0.39 9.3 0.3 1.8 1 1 1 2 2 2 0 AAA domain DUF4795 PF16043.5 GBG74787.1 - 0.61 9.7 6.4 7.1 6.2 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Filament PF00038.21 GBG74787.1 - 0.62 9.6 6.2 1.4 8.4 2.2 2.5 2 1 1 3 3 3 0 Intermediate filament protein EzrA PF06160.12 GBG74787.1 - 0.65 8.1 4.6 2.2 6.3 4.4 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Med9 PF07544.13 GBG74787.1 - 0.68 10.1 7.0 2 8.5 0.8 3.2 3 1 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 RecG_N PF17190.4 GBG74787.1 - 0.86 10.4 3.7 18 6.1 0.3 2.5 2 0 0 2 2 2 0 RecG N-terminal helical domain Rho_Binding PF08912.11 GBG74787.1 - 0.88 10.4 5.0 0.81 10.5 0.6 2.6 2 0 0 2 2 2 0 Rho Binding Secretin_N PF03958.17 GBG74787.1 - 0.91 10.0 3.6 14 6.1 0.2 3.3 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain TMPIT PF07851.13 GBG74787.1 - 1.3 8.2 4.3 7.8 5.6 0.5 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF5082 PF16888.5 GBG74787.1 - 1.5 9.1 5.7 7.5 6.9 2.2 3.4 3 1 1 4 4 3 0 Domain of unknown function (DUF5082) DUF4200 PF13863.6 GBG74787.1 - 1.8 9.0 7.7 6.4 7.2 1.8 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4200) DUF5089 PF17002.5 GBG74787.1 - 2.1 8.2 6.9 2.8 7.8 0.1 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF5089) V-SNARE PF05008.15 GBG74787.1 - 3.6 8.0 9.1 0.17 12.3 0.7 3.2 4 1 0 4 4 2 0 Vesicle transport v-SNARE protein N-terminus HAP2-GCS1 PF10699.9 GBG74789.1 - 8.6e-06 25.6 0.1 1.8e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Male gamete fusion factor Med7 PF05983.11 GBG74789.1 - 0.076 13.1 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 MED7 protein RVT_1 PF00078.27 GBG74792.1 - 1.7e-07 31.0 0.0 2.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG74792.1 - 0.0091 16.2 0.0 0.033 14.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain FoP_duplication PF13865.6 GBG74792.1 - 0.52 10.9 0.1 0.52 10.9 0.1 2.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 SDA1 PF05285.12 GBG74793.1 - 0.1 12.0 9.8 0.15 11.5 9.8 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG74793.1 - 0.15 10.3 8.1 0.18 10.0 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CRT10 PF08728.10 GBG74793.1 - 0.15 10.2 0.1 0.16 10.1 0.1 1.0 1 0 0 1 1 1 0 CRT10 Nop14 PF04147.12 GBG74793.1 - 0.26 9.5 10.0 0.3 9.3 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family SIR4_SID PF16991.5 GBG74793.1 - 3.9 7.5 6.1 6.6 6.8 6.1 1.3 1 0 0 1 1 1 0 Sir4 SID domain Chromo PF00385.24 GBG74795.1 - 8.8e-05 22.3 0.0 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG74795.1 - 0.012 15.3 0.7 0.036 13.9 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) COX16 PF14138.6 GBG74795.1 - 0.088 13.3 3.1 0.56 10.8 3.1 2.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Retrotrans_gag PF03732.17 GBG74795.1 - 0.37 11.1 4.5 0.21 11.9 0.1 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein Ribosomal_L36 PF00444.18 GBG74796.1 - 1e-20 73.6 11.3 1.5e-20 73.1 11.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 NPR3 PF03666.13 GBG74798.1 - 0.35 9.6 1.6 0.49 9.1 1.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 USP7_ICP0_bdg PF12436.8 GBG74800.1 - 3.5e-33 114.9 0.0 2.7e-32 112.0 0.0 2.6 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 Sel1 PF08238.12 GBG74800.1 - 2.9e-29 100.9 9.5 2.8e-11 43.7 0.2 4.0 3 0 0 3 3 3 3 Sel1 repeat USP7_C2 PF14533.6 GBG74800.1 - 1.6e-20 73.7 0.0 1.6e-20 73.7 0.0 4.0 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal TPR_6 PF13174.6 GBG74800.1 - 0.095 13.4 8.1 12 6.7 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ubiquitin PF00240.23 GBG74800.1 - 0.11 12.2 0.2 2.3 8.1 0.0 3.5 3 0 0 3 3 3 0 Ubiquitin family Baculo_PEP_C PF04513.12 GBG74800.1 - 0.15 12.1 0.1 0.15 12.1 0.1 6.6 4 3 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus PRIMA1 PF16101.5 GBG74800.1 - 1.5 8.9 14.1 1 9.4 1.8 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Asp_protease_2 PF13650.6 GBG74801.1 - 2.6e-06 28.0 0.0 6.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74801.1 - 6.3e-06 26.7 0.0 1.9e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74801.1 - 0.00028 20.7 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74801.1 - 0.00055 19.7 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease CENP-K PF11802.8 GBG74801.1 - 0.01 15.5 3.1 0.026 14.1 3.1 1.6 1 0 0 1 1 1 1 Centromere-associated protein K DUF4187 PF13821.6 GBG74801.1 - 0.029 14.1 0.6 0.029 14.1 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) eIF3g PF12353.8 GBG74801.1 - 0.55 10.6 3.1 0.65 10.4 0.2 2.7 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G RT_RNaseH_2 PF17919.1 GBG74802.1 - 2.9e-25 88.2 0.0 7.7e-25 86.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74802.1 - 8.5e-23 80.7 0.0 1.7e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74802.1 - 7.3e-22 78.0 0.1 1.2e-21 77.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG74802.1 - 1.9e-14 53.6 0.0 3.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG74802.1 - 4.5e-11 42.6 0.0 7e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Asp_protease_2 PF13650.6 GBG74802.1 - 4.2e-07 30.5 0.0 8.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74802.1 - 1e-06 29.2 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG74802.1 - 2e-06 27.6 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG74802.1 - 9.5e-06 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease APG17 PF04108.12 GBG74802.1 - 0.034 13.3 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF4886 PF16227.5 GBG74803.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) Pkinase PF00069.25 GBG74804.1 - 4.5e-09 36.0 0.0 6.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG74804.1 - 1.6e-06 27.6 0.0 2.1e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.22 GBG74805.1 - 8.8e-13 47.9 0.1 2.1e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG74805.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 GBG74806.1 - 7.4e-13 48.1 0.1 1.9e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG74806.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif DUF5352 PF17303.2 GBG74807.1 - 4.9 7.0 5.7 1.7 8.5 1.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5352) Histone PF00125.24 GBG74808.1 - 7.1e-15 55.5 0.1 7.1e-15 55.5 0.1 3.8 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 Nipped-B_C PF12830.7 GBG74809.1 - 1.4e-52 178.4 0.0 6.4e-52 176.3 0.0 2.2 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 GBG74809.1 - 4.9e-14 52.3 1.5 7.6e-12 45.3 0.1 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 GBG74809.1 - 9.6e-07 29.0 0.9 0.0052 16.9 0.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 PHD PF00628.29 GBG74809.1 - 2.1e-06 27.5 8.4 4.9e-06 26.3 8.4 1.7 1 0 0 1 1 1 1 PHD-finger HEAT PF02985.22 GBG74809.1 - 0.00012 22.0 2.2 8.9 6.9 0.0 5.6 5 0 0 5 5 4 1 HEAT repeat PHD_2 PF13831.6 GBG74809.1 - 0.0084 15.7 4.3 0.022 14.3 4.3 1.8 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 GBG74809.1 - 0.011 15.6 1.0 0.011 15.6 1.0 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 GBG74809.1 - 0.016 15.4 1.7 0.056 13.6 1.7 1.9 1 0 0 1 1 1 0 PHD-zinc-finger like domain Adaptin_N PF01602.20 GBG74809.1 - 0.022 13.3 2.5 0.14 10.7 0.2 3.0 3 1 0 3 3 3 0 Adaptin N terminal region C1_2 PF03107.16 GBG74809.1 - 0.069 13.5 1.1 0.19 12.1 1.1 1.8 1 0 0 1 1 1 0 C1 domain Zf_RING PF16744.5 GBG74809.1 - 0.32 11.1 6.1 1.8 8.7 6.1 2.3 1 1 0 1 1 1 0 KIAA1045 RING finger zf-HC5HC2H PF13771.6 GBG74809.1 - 0.76 10.1 7.0 2.4 8.4 7.0 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 GBG74809.1 - 3.1 8.2 6.3 10 6.5 6.3 2.0 1 0 0 1 1 1 0 Ring finger domain Peptidase_C48 PF02902.19 GBG74810.1 - 1.6e-05 24.9 0.1 3.1e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Streptin-Immun PF11083.8 GBG74810.1 - 0.064 13.7 0.4 0.15 12.5 0.4 1.6 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein Sec7 PF01369.20 GBG74811.1 - 8.8e-71 237.4 0.1 1.4e-70 236.7 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GBG74811.1 - 1.2e-30 106.5 0.3 1.2e-30 106.5 0.3 2.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GBG74811.1 - 0.0044 16.8 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) PAE PF03283.13 GBG74813.1 - 7e-33 114.2 0.0 2.8e-32 112.2 0.0 1.8 1 1 0 1 1 1 1 Pectinacetylesterase ABC_tran PF00005.27 GBG74813.1 - 1.9e-27 96.5 0.0 3.3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RVT_1 PF00078.27 GBG74813.1 - 1.4e-21 77.0 0.1 2.2e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC2_membrane PF01061.24 GBG74813.1 - 1.2e-10 41.1 23.9 2.5e-10 40.2 23.9 1.5 1 0 0 1 1 1 1 ABC-2 type transporter Rad17 PF03215.15 GBG74813.1 - 0.004 17.1 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 GBG74813.1 - 0.0092 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 GBG74813.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GBG74813.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 GBG74813.1 - 0.024 14.0 0.0 0.055 12.9 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GBG74813.1 - 0.029 14.2 0.0 3.7 7.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GBG74813.1 - 0.069 13.6 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG74813.1 - 0.088 12.6 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG74813.1 - 0.095 13.0 0.2 0.23 11.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG74813.1 - 0.13 12.8 0.4 0.49 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 GBG74813.1 - 1 8.4 22.0 1.8 7.6 22.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Rav1p_C PF12234.8 GBG74814.1 - 5e-63 213.5 0.0 4.1e-57 194.0 0.0 3.4 3 0 0 3 3 3 3 RAVE protein 1 C terminal WD40 PF00400.32 GBG74814.1 - 4.6e-08 33.6 12.1 0.0007 20.4 0.3 7.8 8 0 0 8 8 8 3 WD domain, G-beta repeat RT_RNaseH_2 PF17919.1 GBG74815.1 - 1.1e-14 54.3 0.0 2.3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74815.1 - 1.7e-13 50.8 0.0 4.4e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74815.1 - 2.5e-13 49.9 0.1 7.6e-13 48.4 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74815.1 - 1e-07 32.2 0.0 5.9e-07 29.7 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain gag-asp_proteas PF13975.6 GBG74815.1 - 2.6e-07 31.1 0.2 8.7e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74815.1 - 0.00016 22.2 0.0 0.00045 20.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG74815.1 - 0.0058 16.9 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74815.1 - 0.075 12.8 0.4 0.14 12.0 0.4 1.3 1 0 0 1 1 1 0 Aspartyl protease Peptidase_A2E PF12382.8 GBG74815.1 - 0.23 11.5 0.0 0.43 10.6 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon peptidase Jnk-SapK_ap_N PF09744.9 GBG74815.1 - 0.34 11.1 14.7 0.015 15.6 2.7 3.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 RVT_1 PF00078.27 GBG74816.1 - 2e-09 37.3 0.0 4.5e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0492 PF15744.5 GBG74816.1 - 0.062 12.5 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 ABC_membrane PF00664.23 GBG74818.1 - 4.4e-114 380.8 26.8 4.9e-59 200.2 6.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GBG74818.1 - 2e-71 238.9 0.0 5.3e-35 120.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GBG74818.1 - 4.9e-17 62.1 1.8 1e-05 25.1 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 GBG74818.1 - 3e-09 36.2 1.1 0.0044 15.9 0.1 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 GBG74818.1 - 5.3e-08 33.4 2.7 0.0007 20.0 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GBG74818.1 - 3e-07 30.1 0.7 0.018 14.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG74818.1 - 6e-07 29.8 1.9 0.047 14.0 0.1 3.5 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 GBG74818.1 - 1.2e-05 24.7 2.6 0.27 10.5 0.0 3.5 4 0 0 4 4 4 2 Zeta toxin AAA_30 PF13604.6 GBG74818.1 - 7e-05 22.6 2.2 0.44 10.2 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 GBG74818.1 - 9e-05 22.5 0.6 0.95 9.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 GBG74818.1 - 0.00012 21.9 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 GBG74818.1 - 0.00018 21.6 0.9 0.65 10.1 0.0 3.2 3 0 0 3 3 3 2 Helicase HerA, central domain G-alpha PF00503.20 GBG74818.1 - 0.00032 20.0 0.0 0.24 10.5 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 GBG74818.1 - 0.00037 20.1 2.1 0.41 10.2 0.0 3.8 4 1 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 GBG74818.1 - 0.0005 20.0 0.4 0.73 9.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 GBG74818.1 - 0.00051 20.2 4.7 0.92 9.8 0.7 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 GBG74818.1 - 0.0043 16.9 0.1 0.91 9.4 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_21 PF13304.6 GBG74818.1 - 0.0049 16.7 0.0 8.1 6.2 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 GBG74818.1 - 0.0052 16.5 0.0 3.4 7.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 GBG74818.1 - 0.018 15.6 0.1 8.1 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GBG74818.1 - 0.033 13.7 0.0 5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 GBG74818.1 - 0.037 14.2 0.0 19 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 GBG74818.1 - 0.043 13.6 0.1 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF3987 PF13148.6 GBG74818.1 - 0.069 12.2 0.0 4.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) NACHT PF05729.12 GBG74818.1 - 0.11 12.4 1.4 20 5.1 0.1 3.3 3 0 0 3 3 3 0 NACHT domain DDE_Tnp_4 PF13359.6 GBG74819.1 - 3.9e-28 98.1 0.0 6.6e-26 90.9 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74819.1 - 9.2e-11 41.7 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG74820.1 - 7.2e-07 29.5 1.5 7.2e-07 29.5 1.5 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SDA1 PF05285.12 GBG74820.1 - 4.7 6.6 43.1 0.66 9.3 37.9 2.2 2 0 0 2 2 2 0 SDA1 DUF3915 PF13054.6 GBG74821.1 - 2.8 7.9 12.1 17 5.4 13.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) RVT_1 PF00078.27 GBG74822.1 - 1.2e-22 80.6 0.0 2.8e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74822.1 - 3.5e-17 62.3 0.0 8.6e-17 61.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74822.1 - 3e-06 27.5 0.0 6.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74822.1 - 0.0086 16.7 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74822.1 - 0.016 15.8 0.0 0.035 14.7 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4746 PF15928.5 GBG74822.1 - 1.2 8.5 14.9 1.8 7.9 13.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) TFIIF_alpha PF05793.12 GBG74822.1 - 5.9 5.4 12.7 8.9 4.8 12.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) WD40 PF00400.32 GBG74823.1 - 1.3e-15 57.5 16.5 0.11 13.3 0.0 10.0 9 1 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG74823.1 - 2.9e-13 49.9 0.0 0.003 17.8 0.0 5.6 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GBG74823.1 - 2.7e-09 37.0 0.1 2.5e-06 27.3 0.0 3.2 2 1 1 3 3 3 2 PQQ-like domain PQQ_3 PF13570.6 GBG74823.1 - 8.1e-08 32.5 0.7 0.18 12.3 0.2 5.2 5 0 0 5 5 5 2 PQQ-like domain PQQ PF01011.21 GBG74823.1 - 0.048 13.6 0.0 0.46 10.5 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat Ge1_WD40 PF16529.5 GBG74823.1 - 0.061 12.3 0.1 1 8.3 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MMR_HSR1 PF01926.23 GBG74824.1 - 1.1e-17 64.2 0.1 1.8e-15 57.0 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase GN3L_Grn1 PF08701.11 GBG74824.1 - 7.1e-17 61.3 28.1 7.1e-17 61.3 28.1 5.1 5 1 0 5 5 5 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.18 GBG74824.1 - 3.1e-10 39.8 0.0 8.9e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GBG74824.1 - 5.3e-06 26.1 0.0 0.0013 18.3 0.0 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GBG74824.1 - 1e-05 25.5 0.6 0.0051 16.7 0.6 2.4 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 GBG74824.1 - 0.0023 18.0 3.3 0.0023 18.0 3.3 3.1 2 2 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 GBG74824.1 - 0.054 13.9 0.3 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 GBG74824.1 - 0.055 12.8 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 AIG1 family TPH PF13868.6 GBG74825.1 - 0.0015 17.1 24.1 0.0017 16.9 24.1 1.1 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain HIP1_clath_bdg PF16515.5 GBG74825.1 - 0.077 13.6 10.8 0.1 13.2 10.8 1.3 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMEM215 PF15746.5 GBG74825.1 - 0.11 11.9 0.2 0.12 11.8 0.2 1.0 1 0 0 1 1 1 0 TMEM215 family DUF659 PF04937.15 GBG74826.1 - 4e-34 117.7 0.0 6.2e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Sirohm_synth_C PF14823.6 GBG74826.1 - 0.073 12.7 0.1 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal TPH PF13868.6 GBG74827.1 - 1.8e-09 36.6 102.6 1.8e-09 36.6 102.6 2.5 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain ATP-synt_Eps PF04627.13 GBG74827.1 - 5.5 7.0 8.2 16 5.6 1.3 3.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain RVT_1 PF00078.27 GBG74828.1 - 2.2e-30 105.9 0.1 5.2e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74828.1 - 2.2e-10 40.5 0.0 5.6e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG74828.1 - 3.8e-05 24.2 0.0 0.00012 22.6 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74828.1 - 5.5e-05 23.7 0.0 0.00015 22.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG74828.1 - 0.00018 21.3 0.0 0.00041 20.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74828.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG74828.1 - 0.0024 18.1 0.0 0.019 15.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase CDH1_2_SANT_HL1 PF18375.1 GBG74828.1 - 0.72 10.6 2.1 4.7 8.0 0.0 2.8 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Pkinase PF00069.25 GBG74829.1 - 4e-26 92.0 0.0 5.4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG74829.1 - 8.3e-25 87.5 0.0 1.2e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 GBG74829.1 - 0.012 15.3 0.9 0.012 15.3 0.9 1.9 2 0 0 2 2 2 0 Leucine rich repeat LRRNT_2 PF08263.12 GBG74829.1 - 0.067 13.5 1.3 0.14 12.5 1.3 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Epiglycanin_C PF14654.6 GBG74829.1 - 0.082 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region RVT_1 PF00078.27 GBG74830.1 - 5.5e-34 117.6 0.0 1e-33 116.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74830.1 - 1.7e-30 105.4 0.0 4.2e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74830.1 - 3.8e-29 100.7 0.0 1e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74830.1 - 1.3e-14 54.1 0.1 3.1e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gpUL132 PF11359.8 GBG74830.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Phage_lysozyme PF00959.19 GBG74830.1 - 0.051 14.0 0.3 2.1 8.8 0.0 3.0 3 0 0 3 3 3 0 Phage lysozyme zf-H2C2 PF09337.10 GBG74830.1 - 0.077 13.2 0.1 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger DUF1870 PF08965.10 GBG74830.1 - 0.1 12.6 0.3 0.44 10.6 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) FAM60A PF15396.6 GBG74830.1 - 4.8 7.1 10.7 14 5.6 10.7 1.7 1 0 0 1 1 1 0 Protein Family FAM60A TPR_2 PF07719.17 GBG74831.1 - 2e-14 52.5 0.0 0.00065 19.6 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG74831.1 - 6.6e-12 44.7 0.0 0.031 14.1 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GBG74831.1 - 5.2e-10 39.3 5.9 0.52 11.3 0.0 6.2 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG74831.1 - 3.1e-08 33.2 0.0 0.044 13.5 0.0 4.3 2 1 2 4 4 4 3 TPR repeat TPR_16 PF13432.6 GBG74831.1 - 2e-07 31.5 0.3 0.012 16.3 0.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG74831.1 - 1.3e-05 25.0 0.0 0.15 12.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG74831.1 - 0.00013 22.1 0.7 2.1 8.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG74831.1 - 0.00033 20.8 0.0 0.57 10.4 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG74831.1 - 0.0031 17.8 0.9 11 6.4 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG74831.1 - 0.0047 17.4 0.4 0.89 10.1 0.1 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat Zn_ribbon_2 PF12674.7 GBG74832.1 - 0.11 13.2 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain PP2C PF00481.21 GBG74833.1 - 6.4e-67 225.9 0.0 2.2e-66 224.1 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 GBG74833.1 - 0.00062 19.5 0.1 0.003 17.2 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Spt20 PF12090.8 GBG74833.1 - 2.7 7.5 10.0 4 7.0 10.0 1.2 1 0 0 1 1 1 0 Spt20 family Myb_DNA-bind_4 PF13837.6 GBG74834.1 - 2.7e-07 30.9 2.3 4.1e-07 30.3 2.3 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DNA_pol_A_exo1 PF01612.20 GBG74835.1 - 1.4e-39 135.6 0.0 2.3e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 GBG74835.1 - 1.7e-13 50.3 0.0 3.5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 GBG74835.1 - 3.5e-06 27.6 0.1 1.7e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 PMC2NT (NUC016) domain RVT_1 PF00078.27 GBG74838.1 - 1.3e-28 100.0 0.1 2.2e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG74839.1 - 0.00015 22.0 2.0 0.00039 20.6 0.5 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DDE_Tnp_4 PF13359.6 GBG74840.1 - 1.5e-17 63.7 0.3 4.6e-17 62.1 0.0 1.9 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74840.1 - 1e-08 35.0 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG74840.1 - 0.044 14.1 0.4 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Nop14 PF04147.12 GBG74842.1 - 0.71 8.0 26.7 0.9 7.7 26.7 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG74842.1 - 1.9 8.3 18.3 2.7 7.7 18.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 GBG74842.1 - 3.8 7.0 17.6 5.7 6.4 17.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 GBG74842.1 - 5.2 6.0 10.3 7.3 5.5 10.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 GBG74842.1 - 9.2 5.1 9.3 12 4.7 9.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) EDR1 PF14381.6 GBG74843.1 - 3.5e-28 98.7 0.0 7.8e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 RT_RNaseH PF17917.1 GBG74844.1 - 2.8e-30 104.7 0.0 6.3e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74844.1 - 2.1e-28 98.3 0.0 4.7e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG74844.1 - 0.053 13.1 0.1 0.053 13.1 0.1 3.2 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Integrase_H2C2 PF17921.1 GBG74845.1 - 8.9e-16 57.7 0.5 1.8e-15 56.8 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74845.1 - 5.2e-08 33.1 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain EDR1 PF14381.6 GBG74845.1 - 0.0015 18.3 0.1 0.006 16.3 0.0 2.0 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 RT_RNaseH_2 PF17919.1 GBG74846.1 - 5.9e-31 106.5 0.0 6.2e-30 103.2 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74846.1 - 5.3e-30 103.8 0.0 1.7e-29 102.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG74846.1 - 0.13 11.9 0.0 0.13 11.9 0.0 3.1 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase TMEM100 PF16311.5 GBG74846.1 - 0.69 9.5 2.3 1.5 8.4 2.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 RT_RNaseH_2 PF17919.1 GBG74847.1 - 6.8e-30 103.1 0.0 1.4e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74847.1 - 1.4e-24 86.3 0.0 3.4e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74847.1 - 4.4e-23 82.0 0.1 1.1e-22 80.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG74847.1 - 5.4e-16 58.9 0.0 1.4e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG74847.1 - 7.5e-13 48.4 0.3 2.2e-12 46.9 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG74847.1 - 0.00017 21.8 0.0 0.0011 19.1 0.0 2.4 2 0 0 2 2 2 1 H2C2 zinc finger YabA PF06156.13 GBG74847.1 - 0.0073 16.9 1.1 0.05 14.2 0.0 2.8 3 0 0 3 3 3 1 Initiation control protein YabA Phage_GPO PF05929.11 GBG74847.1 - 0.0078 15.9 7.6 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Phage capsid scaffolding protein (GPO) serine peptidase CENP-H PF05837.12 GBG74847.1 - 0.055 13.9 2.1 0.12 12.8 0.4 2.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) EH_Signature PF15611.6 GBG74847.1 - 0.067 12.6 0.2 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 EH_Signature domain GCN5L1 PF06320.13 GBG74847.1 - 1.2 9.3 11.7 0.63 10.2 6.4 2.8 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) RT_RNaseH PF17917.1 GBG74848.1 - 2.7e-21 75.8 0.0 8.9e-21 74.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74848.1 - 2.9e-20 72.2 0.0 9.7e-20 70.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74848.1 - 2e-19 70.0 0.0 5.7e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG74848.1 - 1.6e-06 28.6 0.0 4.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG74848.1 - 1.1e-05 25.3 0.0 3.8e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG74848.1 - 0.00026 21.5 0.0 0.0011 19.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease WTX PF09422.10 GBG74848.1 - 0.013 14.6 1.0 0.027 13.6 1.0 1.4 1 0 0 1 1 1 0 WTX protein Retrotrans_gag PF03732.17 GBG74848.1 - 0.072 13.4 0.1 0.49 10.7 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG74848.1 - 0.25 11.4 4.1 0.64 10.1 4.1 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation RVT_1 PF00078.27 GBG74849.1 - 4.6e-29 101.5 0.1 7.5e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74849.1 - 3.8e-27 94.3 0.0 1.2e-26 92.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74849.1 - 7.7e-20 71.1 0.0 2.2e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG74849.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG74849.1 - 1.8e-06 28.4 0.0 5e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74849.1 - 2.1e-06 28.3 0.0 6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG74849.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG74849.1 - 0.0011 18.8 0.1 0.0062 16.4 0.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG74849.1 - 0.047 14.0 0.9 0.25 11.6 0.3 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG74850.1 - 6e-83 273.3 0.0 3.1e-28 97.7 0.0 3.9 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74850.1 - 6.2e-67 222.5 2.2 1.1e-24 86.7 0.0 5.0 4 1 1 5 5 4 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74850.1 - 3e-34 116.9 3.8 4.8e-17 61.8 0.2 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG74850.1 - 5e-13 49.1 0.8 2.8e-12 46.7 0.3 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG74850.1 - 7.6e-07 29.7 0.7 1.5e-06 28.7 0.0 1.9 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74850.1 - 3.5e-06 27.5 2.2 7e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG74850.1 - 3.9e-05 23.5 0.0 0.0075 16.2 0.0 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG74850.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG74850.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG74850.1 - 0.018 15.2 0.3 1.4 9.2 0.1 2.9 2 0 0 2 2 2 0 H2C2 zinc finger DUF1564 PF07600.11 GBG74850.1 - 0.023 14.4 0.0 0.064 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) DUF3863 PF12979.7 GBG74850.1 - 0.082 11.8 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3863) tRNA_deacylase PF04414.12 GBG74850.1 - 0.14 11.7 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 D-aminoacyl-tRNA deacylase Mcp5_PH PF12814.7 GBG74850.1 - 1.2 9.3 3.1 2.3 8.3 0.3 2.4 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology RT_RNaseH PF17917.1 GBG74851.1 - 4e-30 104.2 0.3 2.1e-29 101.9 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74851.1 - 6.3e-30 103.2 0.1 2e-29 101.6 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG74851.1 - 1.2e-13 51.2 0.0 5e-13 49.2 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG74851.1 - 1.2e-09 38.4 0.3 6.5e-09 36.0 0.1 2.3 2 0 0 2 2 2 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG74851.1 - 0.00042 20.1 0.4 0.00089 19.0 0.4 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ERF PF04404.12 GBG74851.1 - 0.0028 17.5 0.2 0.0056 16.6 0.2 1.4 1 0 0 1 1 1 1 ERF superfamily SMBP PF16785.5 GBG74851.1 - 4.2 7.6 5.3 2.4 8.4 2.3 2.1 2 0 0 2 2 2 0 Small metal-binding protein RVT_1 PF00078.27 GBG74853.1 - 2.3e-32 112.3 0.0 4.2e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74853.1 - 4.7e-30 103.6 0.0 2.6e-29 101.2 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74853.1 - 1.2e-28 99.5 0.4 4.2e-28 97.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4392 PF14336.6 GBG74853.1 - 0.056 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) RVT_1 PF00078.27 GBG74854.1 - 8.2e-39 133.4 0.1 2.1e-30 105.9 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74854.1 - 2e-23 82.7 0.1 4e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74854.1 - 3.2e-18 65.6 0.0 8.2e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74854.1 - 0.049 14.3 0.0 1.2 9.8 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease RVP_2 PF08284.11 GBG74854.1 - 0.15 11.9 0.0 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease DivIC PF04977.15 GBG74854.1 - 1.3 8.8 9.4 3.5 7.5 9.4 1.7 1 0 0 1 1 1 0 Septum formation initiator RVT_1 PF00078.27 GBG74855.1 - 1.6e-24 86.6 0.0 2.9e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74855.1 - 1.8e-17 63.2 0.0 4.9e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG74855.1 - 1.4e-08 34.6 0.0 2.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG74855.1 - 3.4e-08 33.7 0.0 8.8e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG74855.1 - 1.4e-07 32.0 0.0 3.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74855.1 - 3.2e-06 27.6 0.0 8.7e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG74855.1 - 0.00023 21.0 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Pkinase_Tyr PF07714.17 GBG74857.1 - 7.7e-50 169.6 0.1 1.5e-39 135.9 0.0 3.8 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 GBG74857.1 - 3.7e-40 137.9 0.0 3.7e-34 118.3 0.0 3.6 3 0 0 3 3 3 2 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG74857.1 - 9.9e-31 105.7 0.0 3.3e-16 59.1 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74857.1 - 3.1e-27 94.9 0.3 3.4e-19 69.1 0.4 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74857.1 - 3e-25 89.0 0.3 1e-13 51.3 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74857.1 - 5.7e-10 39.2 0.0 1.5e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG74857.1 - 0.0014 19.2 0.0 0.41 11.2 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG74857.1 - 0.0042 16.9 0.1 0.032 14.0 0.1 2.1 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG74857.1 - 0.0058 17.2 0.0 1.5 9.5 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease Peptidase_A3 PF02160.15 GBG74857.1 - 0.044 13.3 1.1 17 4.9 0.0 3.6 3 0 0 3 3 3 0 Cauliflower mosaic virus peptidase (A3) rve PF00665.26 GBG74858.1 - 8.7e-09 35.6 0.1 2e-08 34.5 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG74858.1 - 0.0002 21.2 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-CCHC_5 PF14787.6 GBG74859.1 - 0.051 13.3 1.7 0.051 13.3 1.7 1.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 GBG74859.1 - 0.31 11.4 4.3 0.1 13.0 1.2 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 GBG74859.1 - 2.1 8.6 8.2 0.5 10.5 4.7 1.8 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG74860.1 - 5.7e-06 26.8 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74860.1 - 0.00085 19.9 0.0 0.0023 18.5 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74860.1 - 0.0077 16.5 1.5 0.036 14.3 1.5 2.1 1 1 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG74860.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG74862.1 - 4.3e-29 100.9 0.0 1.3e-28 99.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74862.1 - 8.1e-29 99.6 0.0 2.4e-28 98.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74862.1 - 6.8e-16 58.1 0.6 1.7e-15 56.9 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG74862.1 - 3.4e-05 24.0 1.5 5.6e-05 23.3 0.1 2.2 2 0 0 2 2 2 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG74862.1 - 0.001 19.3 0.0 0.001 19.3 0.0 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein rve PF00665.26 GBG74862.1 - 0.077 13.2 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain REV PF00424.18 GBG74862.1 - 1.3 9.1 5.1 0.57 10.2 0.9 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) NPV_P10 PF05531.12 GBG74862.1 - 6.7 7.2 5.8 1.4 9.5 0.2 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG74863.1 - 7.8e-06 25.6 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG74863.1 - 0.071 13.3 0.0 0.36 11.0 0.0 2.2 1 1 1 2 2 2 0 Integrase core domain gag-asp_proteas PF13975.6 GBG74866.1 - 0.00023 21.6 0.0 0.00053 20.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74866.1 - 0.011 16.3 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG74867.1 - 1.7e-10 40.9 0.0 1.7e-10 40.9 0.0 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG74867.1 - 2.5e-09 37.4 0.1 3.2e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG74867.1 - 2.6e-07 30.4 0.1 4.7e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG74867.1 - 0.002 18.3 0.0 0.0052 17.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG74868.1 - 2.4e-95 313.1 0.0 1.6e-29 101.9 0.0 4.7 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74868.1 - 1.1e-80 266.7 0.3 7.8e-25 87.2 0.0 4.6 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74868.1 - 1.6e-78 263.3 3.0 2.9e-21 76.0 0.1 5.5 5 0 0 5 5 5 4 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG74868.1 - 1.3e-18 67.0 0.0 2.8e-08 33.6 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease rve PF00665.26 GBG74868.1 - 5e-17 62.2 0.0 3.5e-07 30.4 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain Asp_protease_2 PF13650.6 GBG74868.1 - 5.3e-17 62.2 0.0 4e-07 30.6 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease Integrase_H2C2 PF17921.1 GBG74868.1 - 9.1e-17 60.9 0.4 2.1e-16 59.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG74868.1 - 2.2e-13 50.6 0.0 6.7e-06 26.6 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG74868.1 - 7.4e-07 29.0 0.0 0.0029 17.4 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease Retrotrans_gag PF03732.17 GBG74868.1 - 5.7e-05 23.3 1.0 0.045 14.0 0.1 3.4 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG74868.1 - 0.035 14.3 0.0 0.09 13.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger zf-HC2 PF13490.6 GBG74868.1 - 0.068 13.4 1.3 0.37 11.1 0.4 2.8 2 0 0 2 2 2 0 Putative zinc-finger Integrin_b_cyt PF08725.11 GBG74868.1 - 0.15 11.8 0.1 24 4.7 0.0 2.7 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain RVT_1 PF00078.27 GBG74869.1 - 2.7e-71 239.6 0.6 1.3e-25 90.2 0.1 3.4 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74869.1 - 3.8e-25 88.2 0.0 9e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74869.1 - 4.8e-24 84.3 0.0 1.2e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG74869.1 - 3.1e-08 33.8 9.5 0.0058 16.9 0.0 5.6 5 0 0 5 5 5 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG74869.1 - 0.00019 21.2 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4187 PF13821.6 GBG74869.1 - 0.0095 15.7 1.0 0.054 13.3 1.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) CAMP_factor PF07373.11 GBG74869.1 - 0.011 15.4 0.4 0.025 14.2 0.4 1.5 1 0 0 1 1 1 0 CAMP factor (Cfa) HSBP1 PF06825.12 GBG74869.1 - 0.15 11.9 0.2 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Csm1_N PF18504.1 GBG74869.1 - 0.26 11.6 4.0 0.48 10.8 1.4 2.9 1 1 1 2 2 2 0 Csm1 N-terminal domain Fib_alpha PF08702.10 GBG74869.1 - 3.3 7.9 7.2 0.63 10.2 1.2 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family RT_RNaseH_2 PF17919.1 GBG74871.1 - 3.8e-27 94.2 0.0 6.1e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74871.1 - 4.6e-27 94.3 0.0 7.4e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74871.1 - 9.1e-10 38.4 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74872.1 - 5.6e-32 109.8 0.1 1.1e-31 108.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74872.1 - 8.2e-30 104.0 0.0 1.5e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74872.1 - 2.7e-19 69.4 0.0 5.4e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74872.1 - 2.4e-18 66.0 0.0 4.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74872.1 - 1.8e-08 34.6 0.0 5e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74872.1 - 0.046 13.9 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Dimer_Tnp_hAT PF05699.14 GBG74874.1 - 0.027 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Tup_N PF08581.10 GBG74875.1 - 0.023 15.0 0.5 0.023 15.0 0.5 2.3 2 0 0 2 2 2 0 Tup N-terminal RT_RNaseH PF17917.1 GBG74878.1 - 1.2e-28 99.4 0.2 2.5e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74878.1 - 2.5e-21 75.6 0.0 4.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74878.1 - 1.4e-17 63.5 0.6 2.9e-17 62.5 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG74878.1 - 0.002 18.3 0.2 0.006 16.8 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Mcp5_PH PF12814.7 GBG74878.1 - 0.024 14.8 0.7 0.059 13.5 0.7 1.6 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology DUF2862 PF11061.8 GBG74878.1 - 0.042 13.7 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) S_100 PF01023.19 GBG74878.1 - 0.049 13.3 0.4 0.52 10.1 0.1 2.6 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain rve PF00665.26 GBG74878.1 - 0.054 13.7 0.1 0.25 11.5 0.1 2.1 2 0 0 2 2 2 0 Integrase core domain LptF_LptG PF03739.14 GBG74879.1 - 1.8e-28 99.4 6.9 1.8e-21 76.4 4.6 2.4 2 0 0 2 2 2 2 Lipopolysaccharide export system permease LptF/LptG Retrotrans_gag PF03732.17 GBG74879.1 - 0.071 13.4 0.8 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG74880.1 - 2e-07 31.5 0.1 5.6e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74880.1 - 5.2e-06 27.0 0.2 1.4e-05 25.6 0.1 1.8 1 1 1 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG74880.1 - 2e-05 24.4 0.1 2.9e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG74880.1 - 0.00026 20.8 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease F-box-like PF12937.7 GBG74881.1 - 2.6e-08 33.6 0.8 4.7e-08 32.8 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG74881.1 - 5.6e-07 29.3 0.1 1.1e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain UN_NPL4 PF11543.8 GBG74881.1 - 1.2e-05 25.7 0.0 2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF659 PF04937.15 GBG74882.1 - 1.8e-16 60.3 0.0 2.5e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG74883.1 - 3.3e-23 82.0 0.0 1.2e-22 80.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74883.1 - 1.3e-20 73.3 0.0 3.3e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74883.1 - 3.6e-12 46.2 0.2 7.1e-12 45.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74883.1 - 2.5e-09 37.3 0.0 6.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG74883.1 - 1.6e-06 28.6 0.1 8.7e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74883.1 - 0.00025 21.6 0.1 0.0013 19.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG74883.1 - 0.00032 20.9 5.0 0.00032 20.9 5.0 2.1 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 zf-H2C2 PF09337.10 GBG74883.1 - 0.043 14.0 0.7 0.091 13.0 0.7 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 GBG74883.1 - 0.086 13.2 0.0 0.38 11.1 0.0 2.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Luciferase_N PF05295.11 GBG74883.1 - 0.2 11.7 0.3 0.82 9.7 0.1 2.1 2 0 0 2 2 1 0 Luciferase/LBP N-terminal domain Csm1_N PF18504.1 GBG74883.1 - 0.25 11.7 2.4 0.84 10.0 2.4 1.9 1 0 0 1 1 1 0 Csm1 N-terminal domain YGGT PF02325.17 GBG74887.1 - 2.8e-15 56.5 5.5 4.7e-15 55.8 5.5 1.4 1 0 0 1 1 1 1 YGGT family rve PF00665.26 GBG74888.1 - 7e-07 29.4 0.0 6.5e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Integrase core domain Med26 PF08711.11 GBG74889.1 - 0.0026 17.7 0.3 0.0056 16.7 0.0 1.7 2 0 0 2 2 2 1 TFIIS helical bundle-like domain RVT_1 PF00078.27 GBG74890.1 - 6.6e-25 87.9 0.0 1.3e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74890.1 - 3.5e-23 81.9 0.1 8.1e-22 77.5 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74890.1 - 3.2e-21 75.2 0.0 8.3e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74890.1 - 1.5e-11 44.2 0.0 3.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG74890.1 - 9.2e-08 31.9 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74890.1 - 7.9e-07 29.6 0.0 2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74890.1 - 6e-05 23.5 0.0 0.00029 21.3 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG74890.1 - 0.00025 20.9 0.1 0.00055 19.8 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG74890.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74890.1 - 0.0087 16.3 0.8 0.053 13.8 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG74890.1 - 0.0097 15.8 0.0 0.028 14.3 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG74892.1 - 4.2e-23 82.0 0.0 7.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG74892.1 - 1.1e-12 47.6 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain VirDNA-topo-I_N PF09266.10 GBG74892.1 - 0.15 12.2 0.1 28 5.0 0.0 2.5 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal DUF296 PF03479.15 GBG74893.1 - 3.8e-24 85.1 0.8 8.3e-24 84.0 0.8 1.6 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain AT_hook PF02178.19 GBG74893.1 - 8.3 6.7 23.8 5.9 7.1 7.2 2.8 2 0 0 2 2 2 0 AT hook motif RVT_1 PF00078.27 GBG74895.1 - 4.9e-08 32.8 0.0 7.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RecX PF02631.16 GBG74896.1 - 0.028 14.9 0.3 0.028 14.9 0.3 3.0 3 1 0 3 3 3 0 RecX family Pep_deformylase PF01327.21 GBG74896.1 - 0.25 11.0 2.0 0.55 9.8 2.0 1.5 1 0 0 1 1 1 0 Polypeptide deformylase IL32 PF15225.6 GBG74896.1 - 0.74 10.2 4.9 0.16 12.3 0.7 2.0 2 0 0 2 2 2 0 Interleukin 32 CPSF100_C PF13299.6 GBG74896.1 - 5.3 7.2 13.2 14 5.9 4.4 2.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RestrictionSfiI PF11487.8 GBG74897.1 - 0.046 13.6 1.8 0.071 13.0 1.8 1.2 1 0 0 1 1 1 0 Type II restriction enzyme SfiI Endomucin PF07010.12 GBG74897.1 - 0.22 11.5 10.1 0.34 10.9 10.1 1.2 1 0 0 1 1 1 0 Endomucin Btz PF09405.10 GBG74898.1 - 9.3e-17 61.5 2.8 9.3e-17 61.5 2.8 2.4 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Suf PF05843.14 GBG74899.1 - 0.17 11.9 4.7 0.13 12.2 1.9 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.19 GBG74899.1 - 8.1 7.1 7.4 9.5 6.9 0.4 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein RVT_1 PF00078.27 GBG74900.1 - 5.3e-34 117.7 0.1 9.6e-34 116.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74900.1 - 3.5e-29 101.2 0.0 8.6e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74900.1 - 1e-28 99.3 0.0 2.7e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74900.1 - 1.8e-09 37.6 0.0 4.3e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG74900.1 - 4.5e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74900.1 - 0.0042 17.7 0.0 0.01 16.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74900.1 - 0.033 14.4 0.0 1.2 9.4 0.0 3.7 3 0 0 3 3 3 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG74900.1 - 0.079 13.5 0.0 0.3 11.7 0.0 2.0 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Pkinase PF00069.25 GBG74901.1 - 4.2e-47 160.7 0.0 3.2e-31 108.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG74901.1 - 1.5e-43 149.0 0.0 2.1e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG74901.1 - 0.00031 20.7 0.5 0.0012 18.8 0.5 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DNA_pol_phi PF04931.13 GBG74901.1 - 6.6 4.7 15.6 10 4.1 15.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG74901.1 - 8.9 4.4 11.6 13 3.8 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG74902.1 - 3.9e-26 92.0 0.1 7.7e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74902.1 - 1.2e-18 66.9 0.0 2.4e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG74902.1 - 2.9e-13 49.5 0.0 5.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG74902.1 - 6.5e-12 45.4 0.2 3.3e-11 43.1 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG74902.1 - 7.9e-09 35.7 0.1 2.8e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG74902.1 - 2.3e-08 34.3 0.0 5.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG74902.1 - 0.0092 16.2 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger PaO PF08417.12 GBG74903.1 - 2.2e-10 40.5 0.0 4.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase DUF5427 PF10310.9 GBG74904.1 - 1 8.3 13.6 1.2 8.0 13.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Nop14 PF04147.12 GBG74904.1 - 2.4 6.3 29.3 2.6 6.1 29.3 1.0 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 GBG74904.1 - 2.4 8.2 22.6 2.8 8.0 22.6 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4407 PF14362.6 GBG74904.1 - 4.1 6.7 5.8 4.5 6.5 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_pol_Rpc4 PF05132.14 GBG74904.1 - 6.5 7.2 13.4 7.7 6.9 13.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 GBG74904.1 - 6.5 5.4 15.4 7.6 5.2 15.4 1.0 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG74905.1 - 2.4e-21 75.6 0.0 9.7e-21 73.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74905.1 - 6.2e-21 74.7 0.0 1.6e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG74905.1 - 5.3e-19 68.1 0.4 1.3e-18 66.9 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG74905.1 - 2.9e-08 34.2 0.0 6.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74905.1 - 1.8e-07 31.6 0.0 4.7e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG74905.1 - 1.4e-05 24.9 0.0 3.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG74905.1 - 4.1e-05 23.4 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74905.1 - 7.7e-05 22.9 1.5 0.3 11.4 0.0 3.8 3 0 0 3 3 3 1 Retrotransposon gag protein rve PF00665.26 GBG74905.1 - 9e-05 22.7 0.1 0.00035 20.8 0.1 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG74905.1 - 0.0033 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG74905.1 - 0.0048 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG74905.1 - 0.018 14.9 0.2 0.039 13.9 0.2 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain SARA PF11409.8 GBG74905.1 - 0.22 11.7 2.9 15 5.9 0.9 4.3 3 0 0 3 3 3 0 Smad anchor for receptor activation (SARA) Rieske PF00355.26 GBG74906.1 - 3.1e-10 39.9 0.0 6.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain RT_RNaseH_2 PF17919.1 GBG74907.1 - 5.1e-19 68.2 0.0 1.2e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74907.1 - 3.2e-18 66.1 0.0 5.1e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74907.1 - 1.1e-11 45.0 0.0 2.9e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG74907.1 - 9.2e-09 35.2 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG74907.1 - 5.8e-07 30.1 0.0 1.3e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG74907.1 - 2.3e-05 24.8 0.0 5.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG74907.1 - 0.00036 20.3 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG74907.1 - 0.038 14.6 0.2 0.038 14.6 0.2 3.2 3 0 0 3 3 3 0 SlyX Glyco_hyd_101C PF17451.2 GBG74907.1 - 0.065 13.5 1.3 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Rieske PF00355.26 GBG74908.1 - 2e-21 75.8 0.0 4.1e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG74908.1 - 3.6e-10 39.8 0.0 9.7e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Pheophorbide a oxygenase Nop14 PF04147.12 GBG74909.1 - 0.016 13.5 12.2 0.017 13.4 12.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG74909.1 - 0.13 11.6 13.6 0.15 11.5 13.6 1.1 1 0 0 1 1 1 0 SDA1 DUF4820 PF16091.5 GBG74909.1 - 0.26 10.6 2.9 0.29 10.4 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Astro_capsid_p PF12226.8 GBG74909.1 - 3.4 6.7 16.7 4.4 6.4 16.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CobT PF06213.12 GBG74909.1 - 9.9 5.5 21.4 15 4.9 21.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT LMBR1 PF04791.16 GBG74911.1 - 0.0053 15.7 8.0 0.0083 15.1 8.0 1.4 1 0 0 1 1 1 1 LMBR1-like membrane protein RVT_1 PF00078.27 GBG74912.1 - 1.1e-77 260.5 2.0 7.6e-28 97.5 0.2 3.4 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG74912.1 - 3.9e-28 97.4 0.0 2.1e-26 91.9 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74912.1 - 1.7e-23 82.9 0.0 3.5e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74912.1 - 2.9e-21 75.9 0.0 7.3e-08 32.6 0.0 3.7 3 0 0 3 3 3 3 Integrase core domain Integrase_H2C2 PF17921.1 GBG74912.1 - 2.1e-18 66.2 0.5 6.1e-18 64.7 0.5 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1758 PF05585.12 GBG74912.1 - 0.025 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Retrotrans_gag PF03732.17 GBG74912.1 - 0.034 14.4 0.0 0.16 12.3 0.0 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG74912.1 - 0.064 13.2 1.0 0.16 11.9 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG74913.1 - 2.7e-42 144.8 0.1 1.8e-23 83.3 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74913.1 - 4.9e-35 119.4 3.3 1.2e-16 60.5 0.2 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG74913.1 - 4.2e-22 78.1 0.0 9.8e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74913.1 - 7.7e-21 74.4 0.0 2e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG74913.1 - 5e-20 71.9 0.0 1.3e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG74913.1 - 4.9e-06 26.7 0.0 0.00035 20.8 0.0 3.6 2 1 1 3 3 3 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG74913.1 - 1.3e-05 24.9 1.1 0.00012 21.7 0.4 2.8 3 0 0 3 3 2 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG74913.1 - 0.0017 18.0 12.8 0.26 11.3 1.6 3.0 2 0 0 2 2 2 2 AT hook motif Retrotrans_gag PF03732.17 GBG74913.1 - 0.0054 17.0 13.6 0.16 12.3 0.1 5.4 5 0 0 5 5 5 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG74913.1 - 0.034 14.4 0.1 0.67 10.2 0.1 2.7 2 0 0 2 2 2 0 H2C2 zinc finger NCE101 PF11654.8 GBG74913.1 - 0.048 13.4 2.4 21 4.9 0.0 3.8 3 0 0 3 3 3 0 Non-classical export protein 1 RVT_1 PF00078.27 GBG74914.1 - 7.3e-31 107.4 0.0 1.3e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74914.1 - 8.4e-15 54.6 0.1 2.9e-14 52.9 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74914.1 - 1.6e-12 47.7 0.0 5.1e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG74914.1 - 0.00017 21.8 0.1 0.00044 20.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG74915.1 - 4.3e-29 100.5 0.1 7.7e-29 99.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74915.1 - 8.3e-29 100.7 0.2 1.4e-28 100.0 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74915.1 - 6.5e-27 93.9 0.2 1.2e-26 93.0 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG74915.1 - 9.1e-14 51.6 0.5 1.6e-13 50.8 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF5095 PF17016.5 GBG74915.1 - 0.84 9.3 2.2 0.79 9.4 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) Dimer_Tnp_hAT PF05699.14 GBG74916.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG74917.1 - 7.4e-17 61.2 0.0 1.6e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74917.1 - 9.8e-16 58.0 0.0 2.3e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG74917.1 - 8.8e-14 51.4 0.2 2.3e-13 50.0 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG74917.1 - 2.6e-12 47.0 0.0 2.6e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74917.1 - 1.6e-05 24.6 0.0 3.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG74917.1 - 0.0005 20.6 0.0 0.0021 18.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74917.1 - 0.0052 17.4 0.0 0.019 15.6 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 GBG74917.1 - 0.027 14.2 0.0 0.089 12.6 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 GBG74917.1 - 0.033 14.4 0.4 0.082 13.1 0.4 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 GBG74917.1 - 0.084 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GBG74917.1 - 2.9 7.8 8.2 0.25 11.2 2.0 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF659 PF04937.15 GBG74918.1 - 1.2e-17 64.2 0.0 1.6e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG74919.1 - 2.1e-29 101.5 0.0 3.2e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74919.1 - 1.3e-26 93.0 0.0 1.9e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74919.1 - 7.6e-10 38.7 0.1 1.2e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG74919.1 - 0.036 13.9 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Ku PF02735.16 GBG74920.1 - 8.6e-47 159.5 0.0 2.3e-46 158.1 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 GBG74920.1 - 2.3e-36 125.6 0.0 3.8e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 GBG74920.1 - 1.5e-13 51.3 0.0 5.2e-13 49.5 0.0 2.0 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 GBG74920.1 - 6.8e-09 35.3 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 GBG74920.1 - 0.12 12.1 0.0 0.46 10.2 0.0 2.0 1 0 0 1 1 1 0 HeH/LEM domain SopD PF11047.8 GBG74920.1 - 0.15 11.3 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Salmonella outer protein D MIF4G PF02854.19 GBG74922.1 - 4.1e-74 248.8 10.6 1.8e-35 122.5 0.1 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 GBG74922.1 - 3.8e-37 128.0 6.8 3.8e-37 128.0 6.8 3.9 3 1 0 3 3 3 1 Up-frameshift suppressor 2 DUF2615 PF11027.8 GBG74922.1 - 1.1 9.4 4.9 0.3 11.2 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Utp14 PF04615.13 GBG74923.1 - 2.7e-155 519.0 87.5 2.7e-155 519.0 87.5 3.1 1 1 1 2 2 2 1 Utp14 protein UQ_con PF00179.26 GBG74924.1 - 2e-21 76.1 0.1 2.7e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Plavaka PF18759.1 GBG74925.1 - 1.7e-10 40.6 0.0 3.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Peptidase_C48 PF02902.19 GBG74925.1 - 3e-05 24.0 0.7 6.4e-05 22.9 0.7 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF507 PF04368.13 GBG74925.1 - 0.061 13.2 0.5 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF507) MAP17 PF15807.5 GBG74925.1 - 0.29 11.4 3.4 0.67 10.2 3.4 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SDA1 PF05285.12 GBG74925.1 - 1.6 8.1 16.7 2.7 7.3 16.7 1.3 1 0 0 1 1 1 0 SDA1 UBX PF00789.20 GBG74926.1 - 2.5e-17 62.8 0.0 2.8e-06 27.4 0.0 3.3 3 0 0 3 3 3 3 UBX domain zf-RING_2 PF13639.6 GBG74926.1 - 2.2e-11 43.9 8.5 3.8e-11 43.1 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GBG74926.1 - 7.1e-08 32.1 5.5 1.3e-07 31.2 5.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GBG74926.1 - 1.2e-07 31.5 8.7 2e-07 30.7 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG74926.1 - 1.7e-06 28.2 9.5 3.3e-06 27.3 9.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GBG74926.1 - 0.00023 20.9 6.5 0.00037 20.3 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG74926.1 - 0.00054 19.9 6.5 0.00093 19.1 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG74926.1 - 0.0008 19.2 8.8 0.0013 18.5 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG74926.1 - 0.014 15.4 5.5 0.031 14.3 5.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 GBG74926.1 - 0.092 12.8 6.0 0.18 11.9 6.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 GBG74926.1 - 0.55 10.3 4.1 1.2 9.3 4.1 1.5 1 0 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 GBG74926.1 - 1.9 8.4 6.4 3.5 7.6 6.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 GBG74926.1 - 9.6 5.9 11.5 1.1 9.0 6.3 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Aldo_ket_red PF00248.21 GBG74928.1 - 3.9e-61 206.8 0.0 1.5e-50 172.1 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Det1 PF09737.9 GBG74929.1 - 1.3e-123 413.1 0.4 2.1e-83 280.7 0.4 2.1 2 0 0 2 2 2 2 De-etiolated protein 1 Det1 DUF659 PF04937.15 GBG74932.1 - 1.2e-20 73.9 0.0 2.4e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3730 PF12530.8 GBG74933.1 - 3.2e-47 161.0 1.2 3.2e-38 131.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3730) HEAT PF02985.22 GBG74933.1 - 0.42 11.0 7.3 2.6 8.5 0.2 4.6 5 0 0 5 5 5 0 HEAT repeat USP7_ICP0_bdg PF12436.8 GBG74934.1 - 1.5e-56 191.4 0.0 1.6e-41 142.2 0.0 3.0 3 0 0 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 GBG74934.1 - 1.4e-41 142.5 0.0 1.3e-39 136.1 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 GBG74934.1 - 1.8e-27 96.5 0.0 2.9e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 GBG74934.1 - 1.7e-15 57.2 0.0 3.6e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 MATH domain UCH_1 PF13423.6 GBG74934.1 - 1.5e-05 24.8 0.1 0.00015 21.5 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RA PF00788.23 GBG74934.1 - 0.0045 17.6 0.3 8.6 7.1 0.1 3.5 4 0 0 4 4 4 2 Ras association (RalGDS/AF-6) domain Ribosomal_60s PF00428.19 GBG74934.1 - 3.5 8.3 13.6 8.8 7.0 13.6 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Hid1 PF12722.7 GBG74935.1 - 7.7 4.5 13.3 11 4.1 13.3 1.2 1 1 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 GBG74935.1 - 8 5.1 15.6 12 4.6 15.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDE_Tnp_4 PF13359.6 GBG74936.1 - 1.6e-32 112.4 0.0 4.1e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74936.1 - 6.4e-15 55.3 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG74936.1 - 1.3e-06 28.3 0.4 0.018 14.7 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG74936.1 - 0.052 13.9 0.0 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain LIM_bind PF01803.16 GBG74937.1 - 1.6e-46 158.8 0.0 1.6e-46 158.8 0.0 6.5 3 1 0 3 3 3 2 LIM-domain binding protein DDHD PF02862.17 GBG74937.1 - 0.0032 17.7 3.2 0.0032 17.7 3.2 4.2 2 1 0 2 2 2 1 DDHD domain HNOBA PF07701.14 GBG74937.1 - 0.067 12.6 0.0 0.067 12.6 0.0 5.3 3 1 0 3 3 3 0 Heme NO binding associated NEMP PF10225.9 GBG74938.1 - 5.9e-37 127.7 7.2 3.5e-36 125.2 4.2 2.3 2 0 0 2 2 2 1 NEMP family UAF_Rrn10 PF05234.11 GBG74938.1 - 0.055 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 UAF complex subunit Rrn10 Hamartin PF04388.12 GBG74938.1 - 0.23 10.1 1.3 0.3 9.7 1.3 1.1 1 0 0 1 1 1 0 Hamartin protein CoA_binding_3 PF13727.6 GBG74938.1 - 5.7 6.9 8.2 8.2 6.4 3.3 2.4 2 1 0 2 2 2 0 CoA-binding domain NEMP PF10225.9 GBG74939.1 - 7.5e-37 127.3 7.6 4.3e-36 124.8 4.6 2.3 2 0 0 2 2 2 2 NEMP family UAF_Rrn10 PF05234.11 GBG74939.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 UAF complex subunit Rrn10 DUF1168 PF06658.12 GBG74941.1 - 0.029 14.2 2.4 0.034 14.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1168) His_Phos_1 PF00300.22 GBG74942.1 - 2.5e-23 82.8 0.0 7.2e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Chorion_2 PF03964.15 GBG74942.1 - 0.18 12.7 24.0 0.9 10.4 12.0 3.4 2 0 0 2 2 2 0 Chorion family 2 PI3K_1B_p101 PF10486.9 GBG74942.1 - 9.1 3.9 8.2 14 3.3 8.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Myb_DNA-bind_4 PF13837.6 GBG74943.1 - 2.5e-07 31.0 2.9 4.1e-07 30.3 2.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG74943.1 - 0.019 15.2 1.1 0.04 14.2 1.1 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CTP_transf_like PF01467.26 GBG74943.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase-like DDE_Tnp_4 PF13359.6 GBG74944.1 - 3.4e-26 91.8 0.0 2e-25 89.3 0.0 2.2 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG74944.1 - 2.9e-08 33.6 0.0 4.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG74944.1 - 8.8e-05 22.2 0.1 0.00061 19.5 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain rRNA_proc-arch PF13234.6 GBG74945.1 - 3e-61 207.7 0.0 4.6e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 GBG74945.1 - 3.1e-51 173.3 0.6 6.1e-51 172.3 0.6 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 GBG74945.1 - 4.4e-18 65.6 0.1 1.2e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG74945.1 - 1.2e-07 32.0 0.0 3e-06 27.5 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG74945.1 - 0.0047 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Plavaka PF18759.1 GBG74946.1 - 4.8e-21 75.3 0.6 4.8e-21 75.3 0.6 1.7 2 0 0 2 2 2 1 Plavaka transposase Histone PF00125.24 GBG74946.1 - 1.6e-20 73.8 1.0 2.6e-20 73.1 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 RRM_1 PF00076.22 GBG74947.1 - 0.076 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.6 GBG74948.1 - 0.11 12.2 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG74948.1 - 0.16 12.1 0.5 0.31 11.2 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle NifQ PF04891.12 GBG74948.1 - 0.58 10.5 4.4 1.7 9.0 0.7 2.8 1 1 1 2 2 2 0 NifQ Med2 PF11214.8 GBG74948.1 - 1.5 9.0 13.7 0.22 11.7 1.8 2.9 2 1 0 2 2 2 0 Mediator complex subunit 2 DUF4559 PF15112.6 GBG74948.1 - 1.8 8.2 8.2 4.4 6.9 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Integrase_H2C2 PF17921.1 GBG74951.1 - 1.7e-12 47.3 1.2 3e-12 46.5 0.4 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG74951.1 - 5.6e-10 39.4 0.0 1.6e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain TMEM247 PF15444.6 GBG74951.1 - 0.2 11.7 1.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 247 DUF4407 PF14362.6 GBG74951.1 - 6.1 6.1 18.1 6.2 6.1 15.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3499 PF12005.8 GBG74951.1 - 6.4 7.4 9.5 2.9 8.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Integrase_H2C2 PF17921.1 GBG74952.1 - 6.5e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG74952.1 - 4.9e-08 33.2 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain PEP-utilisers_N PF05524.13 GBG74953.1 - 0.17 12.1 0.3 0.17 12.1 0.3 2.8 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Itfg2 PF15907.5 GBG74953.1 - 0.23 10.4 2.7 0.61 9.1 1.4 1.9 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 BAF1_ABF1 PF04684.13 GBG74955.1 - 0.062 12.4 16.9 0.098 11.7 16.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nop14 PF04147.12 GBG74955.1 - 0.31 9.2 18.7 0.36 9.0 18.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG74955.1 - 0.41 8.9 14.5 0.52 8.5 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 GBG74955.1 - 1.4 7.3 5.0 1.9 7.0 5.0 1.2 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 GBG74955.1 - 2.3 6.9 11.1 2.7 6.7 11.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5308 PF17233.2 GBG74955.1 - 3.7 7.8 5.4 7.4 6.8 5.4 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5308) BUD22 PF09073.10 GBG74955.1 - 4.3 6.6 18.8 5.6 6.2 18.8 1.1 1 0 0 1 1 1 0 BUD22 Zip PF02535.22 GBG74955.1 - 6.8 5.8 7.6 8.9 5.4 7.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GBG74955.1 - 7 5.3 11.7 9.5 4.9 11.7 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 GBG74955.1 - 9.1 5.2 7.7 12 4.7 7.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Fzo_mitofusin PF04799.13 GBG74956.1 - 0.014 15.0 0.5 0.014 15.0 0.5 2.4 2 1 0 2 2 2 0 fzo-like conserved region T3SS_ExsE PF18286.1 GBG74956.1 - 0.028 14.3 0.6 0.21 11.6 0.2 2.3 2 0 0 2 2 2 0 Type III secretion system ExsE HLH PF00010.26 GBG74957.1 - 1.1e-07 31.7 0.2 2e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 GBG74958.1 - 1.1e-07 31.7 0.2 1.9e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RT_RNaseH_2 PF17919.1 GBG74959.1 - 1.3e-26 92.5 0.0 2.4e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74959.1 - 2.1e-23 82.6 0.0 4.7e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74959.1 - 1.4e-09 37.8 0.1 2.3e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG74959.1 - 1.9 6.7 8.0 3.5 5.8 8.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG74959.1 - 5.1 5.2 10.8 7.7 4.6 10.8 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG74959.1 - 8.4 5.6 18.2 7.1 5.8 12.9 2.1 2 0 0 2 2 2 0 BUD22 RVT_1 PF00078.27 GBG74960.1 - 3.3e-10 39.9 0.1 4.8e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) N_BRCA1_IG PF16158.5 GBG74961.1 - 2.8e-29 101.8 0.0 5.8e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 GBG74961.1 - 8.6e-10 38.4 0.5 1.6e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 PB1 domain ZZ PF00569.17 GBG74961.1 - 2.6e-08 33.5 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type UBA PF00627.31 GBG74961.1 - 0.2 11.6 1.1 6.7 6.7 0.0 3.2 3 0 0 3 3 3 0 UBA/TS-N domain N_BRCA1_IG PF16158.5 GBG74962.1 - 2.8e-29 101.9 0.0 5.6e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 GBG74962.1 - 8.3e-10 38.5 0.5 1.6e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 PB1 domain ZZ PF00569.17 GBG74962.1 - 2.5e-08 33.6 0.0 4.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type UBA PF00627.31 GBG74962.1 - 0.18 11.7 1.1 6.6 6.8 0.0 3.2 3 0 0 3 3 3 0 UBA/TS-N domain LDcluster4 PF18306.1 GBG74964.1 - 4e-20 72.0 0.5 4.9e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 SLOG cluster4 family Glycos_transf_2 PF00535.26 GBG74964.1 - 1.9e-10 40.8 0.5 2.3e-06 27.5 0.0 3.8 3 1 0 3 3 3 2 Glycosyl transferase family 2 Methyltransf_23 PF13489.6 GBG74964.1 - 1.2e-06 28.4 0.0 3.5e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Glyco_tranf_2_3 PF13641.6 GBG74964.1 - 1.1e-05 25.4 1.9 0.54 10.1 1.4 4.4 3 1 0 3 3 3 2 Glycosyltransferase like family 2 LSDAT_prok PF18171.1 GBG74964.1 - 0.014 14.6 1.5 0.019 14.2 0.2 1.8 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote Lysine_decarbox PF03641.14 GBG74964.1 - 0.033 14.3 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 Possible lysine decarboxylase PPR_2 PF13041.6 GBG74965.1 - 2.8e-65 216.3 18.7 5.5e-12 45.7 0.1 12.7 6 2 7 13 13 13 10 PPR repeat family PPR PF01535.20 GBG74965.1 - 4.9e-63 205.1 31.5 3.8e-07 29.9 0.0 14.3 14 0 0 14 14 14 11 PPR repeat PPR_1 PF12854.7 GBG74965.1 - 8.7e-46 153.3 17.3 2.4e-07 30.3 0.0 12.2 12 1 0 12 12 12 8 PPR repeat PPR_3 PF13812.6 GBG74965.1 - 3.6e-31 107.0 0.5 6.1e-08 32.6 0.0 7.0 5 1 0 6 6 6 4 Pentatricopeptide repeat domain TPR_14 PF13428.6 GBG74965.1 - 1.7e-08 34.6 11.7 6.2 7.9 0.1 10.0 7 2 3 10 10 10 1 Tetratricopeptide repeat PPR_long PF17177.4 GBG74965.1 - 4e-08 32.9 2.5 0.088 12.2 0.0 4.3 3 2 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG74965.1 - 2.1e-06 28.1 5.5 0.99 10.0 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat DUF2052 PF09747.9 GBG74965.1 - 0.0014 18.8 52.2 0.026 14.6 7.4 4.0 4 0 0 4 4 4 2 Coiled-coil domain containing protein (DUF2052) PKHD_C PF18331.1 GBG74965.1 - 0.07 13.2 0.5 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain TPR_12 PF13424.6 GBG74965.1 - 0.13 12.6 8.9 7.6 6.9 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat Sporozoite_P67 PF05642.11 GBG74965.1 - 0.15 10.1 0.0 0.15 10.1 0.0 4.3 4 1 0 4 4 2 0 Sporozoite P67 surface antigen CDC45 PF02724.14 GBG74965.1 - 0.34 9.1 41.3 0.14 10.5 4.9 3.2 3 0 0 3 3 3 0 CDC45-like protein TPR_2 PF07719.17 GBG74965.1 - 1.7 9.0 4.5 52 4.3 0.5 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG74965.1 - 1.7 8.8 14.2 4.1 7.7 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SDA1 PF05285.12 GBG74965.1 - 2 7.7 47.2 1.4 8.2 8.5 3.4 3 0 0 3 3 3 0 SDA1 Mpp10 PF04006.12 GBG74965.1 - 3.5 5.9 49.6 0.21 10.0 10.9 3.2 3 0 0 3 3 3 0 Mpp10 protein BUD22 PF09073.10 GBG74965.1 - 3.6 6.8 36.9 0.71 9.1 9.6 3.3 3 0 0 3 3 3 0 BUD22 RVT_1 PF00078.27 GBG74966.1 - 1.2e-06 28.2 0.1 2e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG74966.1 - 0.028 14.2 0.0 0.12 12.1 0.0 2.2 3 0 0 3 3 3 0 Retroviral aspartyl protease CDC45 PF02724.14 GBG74966.1 - 1.5 7.0 9.8 2.7 6.2 9.8 1.5 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG74966.1 - 5.8 6.6 16.5 39 3.9 14.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG74966.1 - 6.9 4.7 19.6 10 4.2 19.6 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1295 PF06966.12 GBG74967.1 - 4.6e-80 268.5 8.7 5.5e-80 268.3 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 GBG74967.1 - 2.8e-07 30.6 0.3 7.2e-07 29.3 0.3 1.8 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 GBG74967.1 - 0.001 19.5 0.1 0.001 19.5 0.1 2.4 4 0 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.14 GBG74967.1 - 0.0025 18.2 0.0 0.0025 18.2 0.0 2.8 4 0 0 4 4 4 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1430 PF07242.11 GBG74967.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1430) NIF3 PF01784.18 GBG74968.1 - 0.012 15.2 0.4 0.027 14.1 0.1 1.7 2 0 0 2 2 2 0 NIF3 (NGG1p interacting factor 3) RTP1_C1 PF10363.9 GBG74968.1 - 0.03 14.5 0.0 0.087 13.0 0.0 1.8 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 XRN_M PF17846.1 GBG74968.1 - 0.1 11.5 2.6 0.15 11.0 2.6 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF2408 PF10303.9 GBG74968.1 - 1.1 9.8 6.1 26 5.3 6.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Pkinase PF00069.25 GBG74969.1 - 4.2e-38 131.2 0.0 1.8e-36 125.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG74969.1 - 1.6e-37 129.2 0.0 2.5e-36 125.3 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG74969.1 - 0.00045 19.1 0.0 0.00062 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG74969.1 - 0.00099 19.1 0.0 0.003 17.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GBG74969.1 - 0.04 13.3 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ORMDL PF04061.14 GBG74969.1 - 0.048 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 ORMDL family Pacifastin_I PF05375.13 GBG74972.1 - 5.9e-05 22.7 5.8 0.00015 21.4 5.8 1.7 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) VWC PF00093.18 GBG74972.1 - 3.4 8.1 8.7 0.38 11.1 1.0 2.3 1 1 1 2 2 2 0 von Willebrand factor type C domain KELK PF15796.5 GBG74973.1 - 0.056 13.9 0.8 0.1 13.0 0.8 1.3 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LMWPc PF01451.21 GBG74974.1 - 7.2e-21 75.1 0.0 1.1e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PALP PF00291.25 GBG74975.1 - 3.1e-48 164.7 0.0 4.7e-48 164.1 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_60s PF00428.19 GBG74975.1 - 0.053 14.1 0.5 0.12 13.0 0.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Glucan_synthase PF02364.15 GBG74977.1 - 3.5e-191 637.4 8.9 5.6e-191 636.8 8.9 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Glucan_synthase PF02364.15 GBG74979.1 - 2.5e-20 72.3 0.0 4.7e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Glu_syn_central PF04898.14 GBG74979.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 Glutamate synthase central domain FKS1_dom1 PF14288.6 GBG74980.1 - 4.6e-27 94.9 0.0 1.5e-26 93.3 0.0 1.8 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 gag-asp_proteas PF13975.6 GBG74982.1 - 9.6e-10 38.9 0.2 8.7e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG74982.1 - 6e-07 30.0 0.0 1.6e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG74982.1 - 0.00017 21.3 0.2 0.00038 20.3 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG74982.1 - 0.002 18.4 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Histone PF00125.24 GBG74983.1 - 6.6e-20 71.8 0.1 1.6e-19 70.6 0.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG74983.1 - 0.14 12.6 0.1 0.45 10.9 0.1 1.9 1 0 0 1 1 1 0 CENP-S protein SAPS PF04499.15 GBG74984.1 - 0.023 13.5 0.2 0.02 13.7 0.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MID_MedPIWI PF18296.1 GBG74984.1 - 0.13 12.1 0.8 1.4 8.7 0.9 2.0 2 0 0 2 2 2 0 MID domain of medPIWI RNA_pol_Rpc4 PF05132.14 GBG74984.1 - 0.19 12.2 2.7 0.35 11.3 2.7 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Astro_capsid_p PF12226.8 GBG74984.1 - 0.21 10.7 12.7 0.29 10.2 12.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CPSF100_C PF13299.6 GBG74984.1 - 0.22 11.7 7.2 0.53 10.4 6.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 GBG74984.1 - 0.34 10.7 14.0 4.5 7.0 16.0 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Na_trans_assoc PF06512.13 GBG74984.1 - 0.35 11.1 11.4 0.62 10.3 11.4 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated DUF5523 PF17661.1 GBG74984.1 - 0.48 10.1 18.6 0.98 9.1 18.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Mpp10 PF04006.12 GBG74984.1 - 0.65 8.4 22.8 1.1 7.6 22.8 1.3 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG74984.1 - 0.7 8.0 22.2 1 7.5 22.2 1.2 1 0 0 1 1 1 0 Nop14-like family DinB PF05163.12 GBG74984.1 - 1.1 9.2 5.4 1.9 8.4 5.4 1.4 1 0 0 1 1 1 0 DinB family TFB6 PF17110.5 GBG74984.1 - 1.5 8.5 6.4 3.7 7.3 6.4 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Presenilin PF01080.17 GBG74984.1 - 3.9 6.2 11.7 6.2 5.5 11.7 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 GBG74984.1 - 5.7 5.6 7.8 7.9 5.1 7.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 GBG74984.1 - 8.2 4.4 9.2 12 3.9 9.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ABC_tran PF00005.27 GBG74985.1 - 1e-41 142.7 0.0 8.3e-20 71.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GBG74985.1 - 3.7e-11 43.4 6.8 0.023 14.5 0.0 4.6 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 GBG74985.1 - 1.6e-08 34.4 0.8 1.6e-08 34.4 0.8 3.0 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.19 GBG74985.1 - 9.3e-07 28.5 0.2 0.78 9.1 0.0 4.4 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 GBG74985.1 - 7.3e-06 26.3 1.8 1.5 9.0 0.0 4.3 4 1 0 4 4 4 2 AAA domain AAA_15 PF13175.6 GBG74985.1 - 1.9e-05 24.6 0.6 0.057 13.1 0.2 3.1 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 GBG74985.1 - 5.1e-05 23.2 0.1 0.22 11.4 0.0 3.1 3 0 0 3 3 3 2 NACHT domain AAA_29 PF13555.6 GBG74985.1 - 0.00022 20.9 0.4 0.44 10.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 GBG74985.1 - 0.0003 20.6 0.1 0.31 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GBG74985.1 - 0.00041 20.7 0.0 1.6 9.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 GBG74985.1 - 0.0007 19.8 3.6 0.51 10.5 0.0 3.7 4 1 0 4 4 3 2 AAA domain AAA PF00004.29 GBG74985.1 - 0.00073 20.0 0.2 3.1 8.2 0.0 3.5 4 1 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 GBG74985.1 - 0.00099 19.1 0.2 0.38 10.7 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 GBG74985.1 - 0.0019 18.5 0.4 2 8.7 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG74985.1 - 0.0019 18.6 1.4 2.4 8.5 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 GBG74985.1 - 0.0077 16.3 0.0 3 8.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 GBG74985.1 - 0.0092 15.7 1.3 1.8 8.3 0.1 3.5 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 GBG74985.1 - 0.045 13.3 0.1 1.2 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GBG74985.1 - 0.047 13.6 0.8 6.1 6.7 0.1 3.0 3 0 0 3 3 3 0 NTPase AAA_7 PF12775.7 GBG74985.1 - 0.052 13.1 0.1 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 GBG74985.1 - 0.069 13.2 0.2 6.3 6.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 GBG74985.1 - 0.079 12.6 0.2 2.7 7.6 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 GBG74985.1 - 0.085 12.9 3.3 0.63 10.1 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain Septin PF00735.18 GBG74985.1 - 0.1 11.9 1.4 19 4.4 0.0 3.0 3 0 0 3 3 3 0 Septin TsaE PF02367.17 GBG74985.1 - 0.11 12.6 1.6 3.3 7.7 0.1 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 GBG74985.1 - 0.11 11.7 0.4 7.6 5.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 GBG74985.1 - 0.41 10.7 2.4 8.2 6.5 0.2 3.0 2 1 1 3 3 3 0 Dynamin family AAA_23 PF13476.6 GBG74985.1 - 0.59 10.6 12.9 4.2 7.8 0.2 3.7 3 1 0 3 3 2 0 AAA domain AAA_13 PF13166.6 GBG74985.1 - 1.1 7.8 3.7 9.3 4.7 0.4 3.0 3 1 0 3 3 3 0 AAA domain RT_RNaseH_2 PF17919.1 GBG74987.1 - 9.2e-29 99.4 0.0 1.8e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG74987.1 - 3.7e-23 81.8 0.0 8e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74987.1 - 3.5e-11 43.0 0.1 4.9e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG74987.1 - 0.067 13.1 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) VIR_N PF15912.5 GBG74987.1 - 0.11 12.1 9.0 0.18 11.4 9.0 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Nop14 PF04147.12 GBG74987.1 - 0.6 8.3 18.3 0.78 7.9 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG74987.1 - 0.76 9.1 18.0 1 8.7 18.0 1.1 1 0 0 1 1 1 0 SDA1 PPL5 PF18168.1 GBG74987.1 - 0.78 9.0 2.4 1.1 8.5 2.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 CDC45 PF02724.14 GBG74987.1 - 2.4 6.4 14.3 3.3 5.9 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG74987.1 - 4 7.2 12.1 5.9 6.6 12.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SURF2 PF05477.11 GBG74987.1 - 5.9 6.5 9.9 9.1 5.9 9.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RRM_1 PF00076.22 GBG74988.1 - 0.0072 16.1 0.0 6.3 6.7 0.0 4.3 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim17 PF02466.19 GBG74990.1 - 2.9e-17 63.1 7.7 6.1e-17 62.0 7.7 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Varsurf_PPLC PF03490.13 GBG74990.1 - 0.12 12.4 0.2 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C Nop14 PF04147.12 GBG74991.1 - 2.2 6.4 29.4 0.76 7.9 20.2 2.0 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 GBG74991.1 - 2.3 7.6 31.2 1.2 8.5 21.0 2.1 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 GBG74991.1 - 5 6.4 29.0 2.3 7.4 19.4 2.1 2 0 0 2 2 2 0 BUD22 Toxin_4 PF00706.17 GBG74992.1 - 0.017 15.5 2.1 0.034 14.6 2.1 1.4 1 0 0 1 1 1 0 Anenome neurotoxin BUD22 PF09073.10 GBG74992.1 - 0.1 11.9 15.3 0.14 11.5 15.3 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG74992.1 - 0.1 10.9 11.4 0.2 9.9 11.4 1.4 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG74992.1 - 0.44 9.9 15.6 0.65 9.4 15.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG74992.1 - 2 6.5 17.3 2.6 6.1 17.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG74992.1 - 6.7 4.7 17.7 8.6 4.3 17.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Glyco_transf_34 PF05637.12 GBG74993.1 - 4.3e-22 79.0 0.0 1.1e-21 77.7 0.0 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ODV-E18 PF10717.9 GBG74993.1 - 0.16 11.8 0.2 0.5 10.3 0.1 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 RT_RNaseH PF17917.1 GBG74994.1 - 4.1e-25 88.1 0.0 9.3e-25 87.0 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74994.1 - 1.7e-24 85.7 0.0 3.9e-24 84.6 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74994.1 - 1.2e-13 51.1 0.0 1.8e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG74994.1 - 4.5 6.5 17.5 6.8 5.9 17.5 1.1 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 GBG74994.1 - 5.1 6.1 6.1 7.6 5.5 6.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cwf_Cwc_15 PF04889.12 GBG74994.1 - 6 6.5 12.5 11 5.7 12.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG74994.1 - 6 5.0 7.6 8.9 4.5 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG74996.1 - 2.9e-28 98.9 0.0 9.7e-28 97.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG74996.1 - 4e-19 68.5 0.2 1.2e-18 66.9 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG74996.1 - 2.5e-15 56.6 0.0 6.2e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG74996.1 - 8e-09 35.4 0.0 3.4e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG74996.1 - 1.5e-07 31.6 0.0 4.5e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG74996.1 - 0.0063 17.1 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG74996.1 - 0.019 15.2 7.4 0.05 13.9 0.1 4.5 3 0 0 3 3 3 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG74996.1 - 0.019 15.5 0.0 0.056 14.0 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG74996.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG74998.1 - 4.2e-33 113.4 0.0 1.4e-32 111.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG74998.1 - 4.4e-32 111.4 1.4 1.6e-18 67.0 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG74998.1 - 3e-28 98.2 0.1 8.3e-28 96.8 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG74998.1 - 9.1e-05 22.7 8.5 0.23 11.8 0.0 5.0 4 0 0 4 4 4 2 Retrotransposon gag protein TMEM247 PF15444.6 GBG74998.1 - 0.04 14.0 0.7 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 247 CDH1_2_SANT_HL1 PF18375.1 GBG74998.1 - 0.24 12.1 2.0 8.9 7.1 0.0 3.7 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 zf-CCHC_3 PF13917.6 GBG74998.1 - 0.25 11.4 1.9 0.87 9.6 1.9 2.0 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.11 GBG74998.1 - 6.7 4.9 5.0 11 4.2 5.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HAUS6_N PF14661.6 GBG74998.1 - 7.2 6.1 18.2 1.3 8.6 0.7 3.7 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus PUA_2 PF14306.6 GBG75000.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 PUA-like domain Retrotrans_gag PF03732.17 GBG75001.1 - 1.3e-05 25.4 0.5 7.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein SNAP PF14938.6 GBG75002.1 - 1.8e-102 342.6 17.5 2e-102 342.4 17.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 GBG75002.1 - 1.2e-07 31.2 0.7 0.72 10.0 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG75002.1 - 5.3e-07 29.8 7.9 0.2 12.0 0.2 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 GBG75002.1 - 9.4e-06 25.9 2.8 26 5.7 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 GBG75002.1 - 1e-05 25.3 7.2 0.0014 18.3 0.9 3.1 1 1 2 3 3 3 3 Foie gras liver health family 1 DHR-2 PF06920.13 GBG75002.1 - 2e-05 23.4 1.7 9.9e-05 21.2 1.7 1.9 1 1 0 1 1 1 1 Dock homology region 2 TPR_2 PF07719.17 GBG75002.1 - 0.0013 18.7 10.2 13 6.2 0.0 6.0 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG75002.1 - 0.0015 19.1 6.0 1.3 9.7 0.1 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG75002.1 - 0.0057 17.4 5.2 19 6.4 0.0 4.9 1 1 4 5 5 5 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 GBG75002.1 - 0.011 14.8 0.6 0.011 14.8 0.6 2.2 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_8 PF13181.6 GBG75002.1 - 0.011 15.8 7.0 7.7 7.0 0.1 5.3 3 1 2 5 5 5 0 Tetratricopeptide repeat DUF410 PF04190.13 GBG75002.1 - 0.018 14.8 5.0 0.1 12.4 5.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF410) MIT PF04212.18 GBG75002.1 - 0.38 10.9 8.8 7.3 6.7 0.2 4.0 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 GBG75002.1 - 1.3 9.2 6.5 22 5.3 0.1 2.9 2 2 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 GBG75002.1 - 3.8 7.5 11.7 9.2 6.3 0.0 5.0 5 1 0 6 6 6 0 Tetratricopeptide repeat gag-asp_proteas PF13975.6 GBG75003.1 - 0.00062 20.3 0.1 0.0038 17.7 0.0 2.2 1 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75003.1 - 0.0011 19.6 0.2 0.0063 17.1 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG75003.1 - 0.009 15.7 0.2 0.016 14.8 0.2 1.4 1 0 0 1 1 1 1 Topoisomerase I zinc-ribbon-like Cyt-b5 PF00173.28 GBG75004.1 - 2.5e-09 37.1 0.0 3.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SDA1 PF05285.12 GBG75004.1 - 2.1e-05 24.1 7.1 2.1e-05 24.1 7.1 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GBG75004.1 - 0.00046 19.7 6.4 0.00046 19.7 6.4 1.1 1 0 0 1 1 1 1 BUD22 RPN2_C PF18004.1 GBG75004.1 - 0.028 14.3 8.9 0.041 13.8 8.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 GBG75004.1 - 0.038 12.2 18.1 0.045 12.0 18.1 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 GBG75004.1 - 0.048 13.3 9.8 0.082 12.6 9.8 1.5 1 0 0 1 1 1 0 FAM176 family SpoIIP PF07454.11 GBG75004.1 - 0.064 12.7 4.0 0.083 12.3 4.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RPA43_OB PF17875.1 GBG75004.1 - 0.072 13.7 2.8 0.093 13.4 2.8 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Med17 PF10156.9 GBG75004.1 - 0.072 11.8 2.5 0.063 12.0 2.5 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Presenilin PF01080.17 GBG75004.1 - 0.11 11.2 0.6 0.11 11.3 0.6 1.1 1 0 0 1 1 1 0 Presenilin XAP5 PF04921.14 GBG75004.1 - 0.18 11.6 5.4 0.24 11.2 5.4 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Sigma70_ner PF04546.13 GBG75004.1 - 0.24 11.3 14.7 0.36 10.7 14.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.9 GBG75004.1 - 0.25 10.5 22.1 0.31 10.1 22.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Afi1 PF07792.12 GBG75004.1 - 0.25 11.8 6.5 0.38 11.2 6.5 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CPSF100_C PF13299.6 GBG75004.1 - 0.31 11.2 4.3 0.47 10.6 4.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2428 PF10350.9 GBG75004.1 - 0.33 10.2 1.3 0.43 9.8 1.3 1.1 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Zip PF02535.22 GBG75004.1 - 0.41 9.8 0.5 0.34 10.1 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop53 PF07767.11 GBG75004.1 - 0.48 9.7 18.3 0.38 10.1 17.2 1.4 2 0 0 2 2 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 GBG75004.1 - 0.65 9.8 11.0 0.88 9.3 10.6 1.4 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 PI3K_1B_p101 PF10486.9 GBG75004.1 - 0.79 7.4 6.0 0.9 7.2 6.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit IFT57 PF10498.9 GBG75004.1 - 0.82 8.6 12.1 1.1 8.2 12.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ORC_WH_C PF18137.1 GBG75004.1 - 0.97 9.5 8.3 1.4 8.9 8.3 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Pox_Ag35 PF03286.14 GBG75004.1 - 1.3 8.8 14.0 1.9 8.3 14.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.13 GBG75004.1 - 1.4 7.6 3.5 2 7.1 3.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mpp10 PF04006.12 GBG75004.1 - 1.9 6.8 22.4 2.6 6.4 22.4 1.1 1 0 0 1 1 1 0 Mpp10 protein Connexin PF00029.19 GBG75004.1 - 2 8.1 5.2 2.6 7.7 5.2 1.1 1 0 0 1 1 1 0 Connexin CDC27 PF09507.10 GBG75004.1 - 2.3 7.5 11.2 2.8 7.2 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF913 PF06025.12 GBG75004.1 - 2.4 7.1 5.7 3 6.7 5.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.8 GBG75004.1 - 2.7 6.7 9.5 3.4 6.4 9.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4637 PF15470.6 GBG75004.1 - 3.4 7.4 21.3 5.4 6.7 21.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF5523 PF17661.1 GBG75004.1 - 7.9 6.1 19.7 11 5.6 19.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) TRAP_alpha PF03896.16 GBG75004.1 - 8.4 5.5 13.8 11 5.1 13.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF98 PF01947.16 GBG75006.1 - 0.15 12.0 0.9 0.28 11.1 0.9 1.4 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase RT_RNaseH_2 PF17919.1 GBG75007.1 - 4.9e-25 87.5 0.0 8.2e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75007.1 - 1.8e-23 82.8 0.0 2.9e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75007.1 - 1.9e-08 34.1 0.1 3e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG75007.1 - 0.015 15.6 4.0 0.024 14.9 4.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG75007.1 - 0.21 9.7 8.3 0.29 9.3 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG75007.1 - 1.1 8.6 8.9 1.7 8.0 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ABC_tran PF00005.27 GBG75008.1 - 4.3e-23 82.3 0.0 7e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG75008.1 - 2.7e-13 49.8 9.5 3.9e-13 49.3 9.5 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG75008.1 - 2.4e-08 34.2 0.0 2.3e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GBG75008.1 - 0.01 15.3 0.2 0.63 9.4 0.0 2.6 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GBG75008.1 - 0.016 14.9 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 GBG75008.1 - 0.11 12.3 0.0 7.7 6.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF4162 PF13732.6 GBG75008.1 - 0.12 13.1 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) RT_RNaseH_2 PF17919.1 GBG75009.1 - 1e-29 102.5 0.0 4.1e-29 100.6 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75009.1 - 4.3e-29 100.9 0.1 1.4e-28 99.2 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75009.1 - 2.6e-12 46.7 0.0 6.1e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG75009.1 - 0.0091 15.6 12.7 0.031 13.9 0.0 2.3 2 0 0 2 2 2 1 Phage capsid scaffolding protein (GPO) serine peptidase PA26 PF04636.13 GBG75009.1 - 0.29 10.0 10.5 0.44 9.4 10.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Saccharop_dh_N PF04455.12 GBG75009.1 - 2.3 8.7 0.0 2.3 8.7 0.0 3.2 3 0 0 3 3 3 0 LOR/SDH bifunctional enzyme conserved region FlaC_arch PF05377.11 GBG75010.1 - 0.0054 17.1 0.6 0.0054 17.1 0.6 3.0 3 1 0 3 3 3 1 Flagella accessory protein C (FlaC) HALZ PF02183.18 GBG75010.1 - 0.0074 16.5 2.1 0.027 14.7 0.2 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper Lebercilin PF15619.6 GBG75010.1 - 0.017 14.8 1.3 0.017 14.8 1.3 3.0 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Ufd2P_core PF10408.9 GBG75010.1 - 0.17 10.4 2.6 0.19 10.3 1.1 1.6 2 0 0 2 2 2 0 Ubiquitin elongating factor core Mito_fiss_Elm1 PF06258.11 GBG75010.1 - 0.22 10.6 1.6 0.22 10.6 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial fission ELM1 AKAP95 PF04988.12 GBG75010.1 - 0.75 10.0 5.7 0.14 12.4 2.2 1.6 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) FTO_CTD PF12934.7 GBG75010.1 - 0.86 9.3 7.6 0.12 12.1 2.0 2.2 3 0 0 3 3 3 0 FTO C-terminal domain PEP-utilisers_N PF05524.13 GBG75010.1 - 1.1 9.5 11.0 3.5 7.8 0.2 3.1 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal OmpH PF03938.14 GBG75010.1 - 1.2 9.5 21.7 0.88 9.9 10.9 2.9 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) VSG_B PF13206.6 GBG75010.1 - 1.4 8.1 6.8 0.39 9.9 3.5 1.6 2 0 0 2 2 2 0 Trypanosomal VSG domain Presenilin PF01080.17 GBG75010.1 - 1.8 7.2 5.9 2.5 6.8 5.9 1.1 1 0 0 1 1 1 0 Presenilin Syntaxin_2 PF14523.6 GBG75010.1 - 2 8.8 14.1 1.8 9.0 0.6 3.4 3 1 0 3 3 3 0 Syntaxin-like protein DUF2703 PF10865.8 GBG75010.1 - 2.3 8.4 6.0 0.88 9.8 1.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF2703) ZapB PF06005.12 GBG75010.1 - 4.5 7.8 17.5 12 6.4 6.7 3.3 3 0 0 3 3 3 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 GBG75010.1 - 4.7 7.8 10.6 13 6.4 7.3 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FapA PF03961.13 GBG75010.1 - 6.2 5.3 12.6 0.035 12.7 0.6 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A 4HB_MCP_1 PF12729.7 GBG75010.1 - 6.6 6.2 9.0 1.8 8.1 0.2 3.0 2 1 0 3 3 3 0 Four helix bundle sensory module for signal transduction RT_RNaseH_2 PF17919.1 GBG75011.1 - 9.5e-29 99.4 0.2 2.8e-28 97.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75011.1 - 5e-27 94.3 0.1 1.3e-26 92.9 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75011.1 - 1.3e-19 70.0 0.1 2.8e-19 68.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75011.1 - 5e-13 49.3 0.0 1.8e-12 47.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG75011.1 - 4.2e-11 42.8 0.0 8.8e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG75011.1 - 0.00023 21.3 0.0 0.0006 20.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Sporozoite_P67 PF05642.11 GBG75011.1 - 0.044 11.9 2.7 0.068 11.3 2.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ELFV_dehydrog PF00208.21 GBG75013.1 - 1.8e-64 217.8 0.0 2.7e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 GBG75013.1 - 6.2e-51 171.7 0.0 1.4e-50 170.5 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain RT_RNaseH PF17917.1 GBG75013.1 - 4.7e-25 87.9 0.0 8.8e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75013.1 - 2.2e-23 82.2 0.0 3.9e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75013.1 - 9.3e-17 61.3 0.0 4.2e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-Hacid_dh_C PF02826.19 GBG75013.1 - 0.0083 15.5 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2249 PF10006.9 GBG75013.1 - 0.063 13.2 0.0 18 5.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) RVT_1 PF00078.27 GBG75014.1 - 1.9e-29 102.7 0.2 7.6e-29 100.8 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75014.1 - 3e-21 75.3 0.0 9.2e-21 73.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75014.1 - 6.3e-12 45.7 0.1 4.4e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Tudor-knot PF11717.8 GBG75014.1 - 0.072 13.0 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YrbL-PhoP_reg PF10707.9 GBG75014.1 - 0.13 11.7 1.2 0.34 10.4 1.2 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FAM76 PF16046.5 GBG75014.1 - 0.64 9.3 10.0 1.5 8.1 10.0 1.5 1 0 0 1 1 1 0 FAM76 protein CAC1F_C PF16885.5 GBG75015.1 - 2.7 7.6 16.8 3.4 7.2 16.8 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term PUF PF00806.19 GBG75016.1 - 0.00054 19.5 0.0 1.9 8.3 0.0 4.2 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat SUIM_assoc PF16619.5 GBG75017.1 - 0.0065 16.5 0.4 0.027 14.5 0.4 2.1 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DDE_Tnp_4 PF13359.6 GBG75018.1 - 1.5e-12 47.5 0.0 2.6e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75018.1 - 1.2e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG75018.1 - 0.16 11.6 0.0 4.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain Band_7_C PF16200.5 GBG75019.1 - 2.1e-26 91.7 0.9 6.4e-26 90.2 0.9 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 RVT_1 PF00078.27 GBG75019.1 - 9.9e-26 90.6 0.1 2.5e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75019.1 - 1.6e-20 73.0 0.0 3.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75019.1 - 5.6e-11 42.7 0.0 1.4e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG75019.1 - 0.015 15.6 2.2 0.079 13.3 0.0 3.3 5 0 0 5 5 5 0 Retrotransposon gag protein APG17 PF04108.12 GBG75019.1 - 0.062 12.4 0.2 0.39 9.8 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 gag-asp_proteas PF13975.6 GBG75019.1 - 0.16 12.6 0.0 0.57 10.8 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Peptidase_C33 PF05412.12 GBG75019.1 - 0.17 11.9 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase HIP1_clath_bdg PF16515.5 GBG75019.1 - 0.61 10.7 4.6 0.4 11.3 0.5 2.7 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 GBG75020.1 - 0.00092 19.8 3.7 0.012 16.2 0.4 2.9 2 0 0 2 2 2 1 SlyX Retrotrans_gag PF03732.17 GBG75020.1 - 0.022 15.0 0.8 0.058 13.7 0.0 2.1 2 1 0 2 2 2 0 Retrotransposon gag protein DUF641 PF04859.12 GBG75020.1 - 0.027 14.8 3.4 0.077 13.3 1.0 2.6 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) TRPM_tetra PF16519.5 GBG75020.1 - 0.063 13.4 2.7 1.8 8.7 0.1 3.1 3 1 0 3 3 3 0 Tetramerisation domain of TRPM TolA_bind_tri PF16331.5 GBG75020.1 - 0.68 10.1 7.7 0.34 11.0 3.6 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation Filament PF00038.21 GBG75020.1 - 3.6 7.1 12.3 1.3 8.5 6.9 2.1 1 1 1 2 2 2 0 Intermediate filament protein RT_RNaseH PF17917.1 GBG75021.1 - 1.2e-23 83.4 0.0 2.2e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75021.1 - 2.3e-23 82.1 0.0 6.9e-23 80.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG75021.1 - 3.4e-05 24.4 0.0 6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75021.1 - 6.1e-05 23.5 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG75021.1 - 0.0067 16.2 0.0 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG75021.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Band_7 PF01145.25 GBG75022.1 - 2.8e-25 89.4 0.0 3.7e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family RVT_1 PF00078.27 GBG75023.1 - 0.00026 20.6 1.1 0.0045 16.5 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1664 PF07889.12 GBG75023.1 - 0.0013 18.7 1.2 0.0044 17.0 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 GBG75023.1 - 0.0067 16.5 4.5 0.025 14.7 4.5 2.0 1 0 0 1 1 1 1 TolA binding protein trimerisation Spc29 PF17082.5 GBG75023.1 - 0.02 14.7 0.2 0.04 13.8 0.2 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF2730 PF10805.8 GBG75023.1 - 0.051 13.7 0.2 0.23 11.6 0.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Retrotrans_gag PF03732.17 GBG75023.1 - 0.17 12.2 1.3 1 9.7 0.1 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein HalX PF08663.10 GBG75023.1 - 0.45 10.9 8.0 0.49 10.8 0.4 3.6 4 0 0 4 4 4 0 HalX domain Acyltransf_C PF16076.5 GBG75024.1 - 1.4e-19 70.0 0.0 2.3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 GBG75024.1 - 0.00012 21.7 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 GBG75025.1 - 0.0015 18.1 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase EF-hand_6 PF13405.6 GBG75026.1 - 3e-09 36.1 0.1 6.3e-08 31.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GBG75026.1 - 8.3e-09 34.4 0.1 1.6e-07 30.3 0.0 2.4 2 1 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 GBG75026.1 - 3.2e-08 33.9 0.1 4.1e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GBG75026.1 - 2.6e-05 23.5 0.0 4.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 GBG75026.1 - 0.0064 16.3 0.1 0.019 14.8 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 GBG75026.1 - 0.13 12.6 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain RVT_1 PF00078.27 GBG75028.1 - 9.1e-27 94.0 0.1 1.6e-26 93.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75028.1 - 3.5e-21 75.4 0.1 7.6e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75028.1 - 7.6e-14 51.6 0.6 3.7e-13 49.3 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG75028.1 - 9.7e-12 45.1 0.0 4.5e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG75028.1 - 1e-11 44.7 0.0 2.3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG75028.1 - 0.0015 18.7 0.2 0.0054 16.9 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger Dimer_Tnp_hAT PF05699.14 GBG75030.1 - 0.0069 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG75032.1 - 0.00012 22.6 0.0 0.00026 21.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG75032.1 - 0.0074 16.1 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG75032.1 - 0.011 16.3 0.0 0.031 14.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG75032.1 - 0.013 15.8 0.0 0.042 14.2 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG75032.1 - 0.12 12.7 1.2 0.31 11.3 0.5 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein V_ATPase_I PF01496.19 GBG75032.1 - 2.2 6.1 4.6 0.91 7.4 0.7 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family UQ_con PF00179.26 GBG75033.1 - 6.6e-19 68.0 0.0 1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DNA_photolyase PF00875.18 GBG75033.1 - 0.056 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 DNA photolyase Asp_protease_2 PF13650.6 GBG75034.1 - 1.4e-07 32.1 0.0 2.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG75034.1 - 2.7e-07 30.4 0.0 6.3e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG75034.1 - 1.8e-06 28.4 0.0 3.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG75034.1 - 0.0014 18.5 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Thg1 PF04446.12 GBG75034.1 - 0.051 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 tRNAHis guanylyltransferase RT_RNaseH_2 PF17919.1 GBG75035.1 - 2.2e-40 136.7 0.3 2.7e-23 81.9 0.0 2.4 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75035.1 - 2.2e-36 124.3 0.8 8.8e-23 80.6 0.7 2.4 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75035.1 - 1.2e-19 70.1 0.1 2.7e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG75035.1 - 4.7e-12 45.9 0.3 8.5e-12 45.1 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG75035.1 - 0.085 13.0 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 GBG75035.1 - 0.12 12.6 1.4 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger RVT_1 PF00078.27 GBG75036.1 - 4.1e-36 124.6 0.0 7.3e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75036.1 - 4.6e-28 97.2 0.0 2.5e-27 94.8 0.0 2.4 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75036.1 - 5.2e-28 97.4 0.1 3.5e-27 94.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Uso1_p115_C PF04871.13 GBG75036.1 - 0.0086 16.4 6.1 0.3 11.5 3.6 3.4 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region CDRT4 PF15213.6 GBG75036.1 - 0.019 15.6 1.2 0.057 14.0 1.2 1.8 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein DUF4407 PF14362.6 GBG75036.1 - 0.022 14.1 3.6 0.37 10.1 0.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DinB PF05163.12 GBG75036.1 - 0.034 14.1 2.7 8.1 6.3 0.0 3.7 4 0 0 4 4 4 0 DinB family Phage_GPO PF05929.11 GBG75036.1 - 0.062 12.9 5.3 0.28 10.8 0.0 2.6 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase CLZ PF16526.5 GBG75036.1 - 0.16 12.4 8.0 0.2 12.0 0.0 3.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4392 PF14336.6 GBG75036.1 - 0.17 11.3 0.0 0.45 9.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) NPV_P10 PF05531.12 GBG75036.1 - 1 9.9 3.7 0.7 10.4 0.2 2.6 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein MRPL52 PF18699.1 GBG75036.1 - 1.5 9.0 8.2 37 4.6 0.0 2.6 2 0 0 2 2 2 0 Mitoribosomal protein mL52 RPN7 PF10602.9 GBG75036.1 - 8.1 6.1 7.2 8.4 6.1 5.0 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 zf-CCHC PF00098.23 GBG75037.1 - 4.5e-06 26.5 3.9 1e-05 25.4 3.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG75037.1 - 0.0065 16.3 3.6 0.012 15.4 3.6 1.5 1 0 0 1 1 1 1 Zinc knuckle WDCP PF15390.6 GBG75037.1 - 0.21 9.9 9.7 0.25 9.7 9.7 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family RNA_pol_Rpc4 PF05132.14 GBG75037.1 - 0.45 10.9 11.4 0.077 13.4 5.6 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 XRN_M PF17846.1 GBG75037.1 - 1.8 7.4 10.4 2.3 7.1 10.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain ArAE_2_N PF10337.9 GBG75037.1 - 2 7.3 6.2 2.5 7.0 6.2 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Atg14 PF10186.9 GBG75037.1 - 6.1 5.8 17.7 8.8 5.3 17.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DDT PF02791.17 GBG75039.1 - 0.013 15.8 0.0 8.7 6.7 0.0 2.3 2 0 0 2 2 2 0 DDT domain Asp_protease_2 PF13650.6 GBG75041.1 - 0.0017 18.9 0.0 0.076 13.7 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75041.1 - 0.003 18.1 0.0 0.024 15.2 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease FpoO PF10621.9 GBG75043.1 - 0.009 16.3 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 1 F420H2 dehydrogenase subunit FpoO DUF3215 PF11503.8 GBG75043.1 - 0.11 12.3 0.1 0.77 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) CDH PF02611.15 GBG75043.1 - 0.82 9.2 4.6 11 5.5 0.3 2.1 2 0 0 2 2 2 0 CDP-diacylglycerol pyrophosphatase CENP-F_leu_zip PF10473.9 GBG75043.1 - 1.4 8.9 38.1 2 8.4 8.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 GBG75043.1 - 3.3 7.0 16.9 4.8 6.4 16.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 GBG75043.1 - 3.5 7.8 14.0 0.24 11.6 5.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 GBG75043.1 - 7.8 6.3 8.5 34 4.2 7.2 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Cytochrom_C PF00034.21 GBG75044.1 - 9.2e-13 49.2 0.1 1.3e-12 48.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 GBG75044.1 - 7.1e-06 26.2 3.0 2.2e-05 24.7 3.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GBG75044.1 - 0.0037 17.0 0.2 0.018 14.8 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain Surfac_D-trimer PF09006.11 GBG75044.1 - 0.016 15.1 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Cytochrome_P460 PF16694.5 GBG75044.1 - 0.2 12.0 0.7 2.1 8.7 0.2 2.0 2 0 0 2 2 2 0 Cytochrome P460 BILBO1_N PF18281.1 GBG75045.1 - 0.26 11.7 0.3 0.4 11.1 0.3 1.3 1 0 0 1 1 1 0 BILBO1 N-terminal domain zf-CCHC_2 PF13696.6 GBG75046.1 - 0.0086 15.9 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG75046.1 - 0.11 12.8 0.1 0.62 10.4 0.0 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG75046.1 - 0.25 11.5 0.5 0.53 10.5 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DBINO PF13892.6 GBG75047.1 - 0.0055 17.1 20.4 0.0074 16.7 20.4 1.2 1 0 0 1 1 1 1 DNA-binding domain Paramyxo_ncap PF00973.19 GBG75047.1 - 3.3 6.5 7.3 3.7 6.4 7.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SSB PF00436.25 GBG75049.1 - 6.6e-22 77.5 0.0 1.2e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family Eapp_C PF10238.9 GBG75049.1 - 0.032 14.3 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein zf-CCHC PF00098.23 GBG75050.1 - 1.5 9.0 4.7 0.85 9.8 1.9 2.2 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG75051.1 - 0.00078 20.0 0.0 0.002 18.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75051.1 - 0.00085 19.9 0.0 0.0025 18.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG75051.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG75051.1 - 0.015 15.6 0.1 0.061 13.6 0.0 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 GBG75051.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG75052.1 - 0.055 13.1 0.3 0.055 13.1 0.3 2.0 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG75052.1 - 0.06 13.4 1.9 0.11 12.7 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG75053.1 - 2.4e-26 92.0 0.3 6.3e-25 87.5 0.1 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75053.1 - 7.6e-25 86.9 0.0 3.3e-23 81.6 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75053.1 - 7e-20 70.9 0.5 1.7e-19 69.7 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75053.1 - 5.9e-18 65.2 0.0 1.8e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG75053.1 - 2.9e-12 46.6 0.0 8.2e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG75053.1 - 0.00041 20.5 0.1 0.0012 19.0 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Rhamno_transf PF11316.8 GBG75053.1 - 0.081 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative rhamnosyl transferase LcrG PF07216.12 GBG75053.1 - 0.16 11.9 0.3 0.35 10.8 0.3 1.5 1 0 0 1 1 1 0 LcrG protein Latarcin PF10279.9 GBG75053.1 - 4.5 7.8 5.1 1.2 9.6 0.1 2.6 3 0 0 3 3 3 0 Latarcin precursor Rieske PF00355.26 GBG75054.1 - 7.8e-12 45.0 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 GBG75054.1 - 4.7e-11 43.0 0.0 8.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region LmjF365940-deam PF14421.6 GBG75054.1 - 0.26 10.9 0.7 0.6 9.7 0.7 1.7 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases cwf21 PF08312.12 GBG75055.1 - 2.2 8.5 5.5 1.5 9.0 2.0 2.3 2 0 0 2 2 2 0 cwf21 domain DDE_Tnp_4 PF13359.6 GBG75057.1 - 1.7e-25 89.5 0.0 2.7e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75057.1 - 2e-08 34.1 0.0 3.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein CENP-B_dimeris PF09026.10 GBG75057.1 - 0.48 10.8 8.4 0.92 9.9 8.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Hexokinase_2 PF03727.16 GBG75058.1 - 2.2e-63 213.9 0.0 2.2e-63 213.9 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 GBG75058.1 - 3.1e-55 187.2 0.0 6.5e-55 186.1 0.0 1.5 2 0 0 2 2 2 1 Hexokinase DDE_Tnp_4 PF13359.6 GBG75059.1 - 4.7e-27 94.6 0.0 8.1e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75059.1 - 3.8e-08 33.2 0.0 6.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Leo1 PF04004.13 GBG75061.1 - 0.32 10.8 1.3 0.54 10.1 1.3 1.3 1 0 0 1 1 1 0 Leo1-like protein Integrase_H2C2 PF17921.1 GBG75062.1 - 1.8e-15 56.8 0.1 5.1e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG75062.1 - 2.5e-09 37.0 0.0 4.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG75062.1 - 0.0028 17.8 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Angiomotin_C PF12240.8 GBG75062.1 - 0.006 16.2 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Angiomotin C terminal Pkinase_Tyr PF07714.17 GBG75064.1 - 8.1e-30 104.0 0.1 1e-19 70.8 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 GBG75064.1 - 2.9e-23 82.6 0.0 3.2e-15 56.2 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain SDA1 PF05285.12 GBG75064.1 - 0.0093 15.4 26.4 0.027 13.9 13.3 2.3 2 0 0 2 2 2 2 SDA1 RNA_pol_3_Rpc31 PF11705.8 GBG75064.1 - 0.041 14.1 26.5 0.014 15.7 1.8 3.0 3 0 0 3 3 2 0 DNA-directed RNA polymerase III subunit Rpc31 Mpp10 PF04006.12 GBG75064.1 - 0.27 9.6 34.2 0.27 9.6 18.5 2.2 2 0 0 2 2 2 0 Mpp10 protein Pox_Ag35 PF03286.14 GBG75064.1 - 0.28 11.0 27.7 0.65 9.8 2.0 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Na_trans_assoc PF06512.13 GBG75064.1 - 0.3 11.3 19.8 3.5 7.8 0.7 2.7 2 0 0 2 2 2 0 Sodium ion transport-associated MPP6 PF10175.9 GBG75064.1 - 0.57 10.7 15.4 1.2 9.7 4.5 2.6 2 0 0 2 2 2 0 M-phase phosphoprotein 6 BSP_II PF05432.11 GBG75064.1 - 1.2 8.8 36.9 1.3 8.7 14.1 2.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF2052 PF09747.9 GBG75064.1 - 3.1 7.9 35.2 0.023 14.8 9.7 2.7 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SURF2 PF05477.11 GBG75064.1 - 3.9 7.1 18.2 1.8 8.2 8.2 2.5 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Sigma70_ner PF04546.13 GBG75064.1 - 4.1 7.2 25.8 0.44 10.4 3.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region CPSF100_C PF13299.6 GBG75064.1 - 5.1 7.2 23.4 2.7 8.2 0.6 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Roughex PF06020.11 GBG75064.1 - 6.2 5.8 26.5 8.7 5.3 3.1 2.6 2 0 0 2 2 2 0 Drosophila roughex protein Radial_spoke PF04712.12 GBG75064.1 - 9.2 5.1 31.4 0.051 12.5 6.4 2.3 2 0 0 2 2 2 0 Radial spokehead-like protein DUF1840 PF08895.11 GBG75064.1 - 9.2 6.7 19.4 0.21 11.9 1.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) RT_RNaseH_2 PF17919.1 GBG75065.1 - 6.4e-27 93.5 0.0 2.7e-26 91.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75065.1 - 5.8e-24 84.4 0.0 2.4e-23 82.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG75065.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG75065.1 - 0.0018 18.8 0.0 0.016 15.8 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG75065.1 - 0.0045 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG75065.1 - 0.0095 16.6 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG75065.1 - 0.029 14.2 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.27 GBG75065.1 - 0.069 12.7 0.2 0.16 11.5 0.2 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG75068.1 - 4.4e-51 173.8 0.0 6.8e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG75068.1 - 9e-45 153.0 0.0 1.8e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG75068.1 - 0.0036 16.1 0.0 0.0085 14.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase gag-asp_proteas PF13975.6 GBG75069.1 - 0.00063 20.3 0.0 0.0019 18.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75069.1 - 0.0057 17.3 0.0 0.014 16.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG75069.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF659 PF04937.15 GBG75070.1 - 8.2e-13 48.5 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PPR PF01535.20 GBG75071.1 - 1.3e-15 56.4 14.5 0.0064 16.7 0.5 9.9 9 0 0 9 9 9 4 PPR repeat LAGLIDADG_2 PF03161.13 GBG75071.1 - 2.3e-14 53.8 0.0 4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 LAGLIDADG DNA endonuclease family PPR_2 PF13041.6 GBG75071.1 - 3.9e-11 43.0 7.1 0.00017 21.7 0.2 6.6 5 2 2 7 7 7 3 PPR repeat family PPR_long PF17177.4 GBG75071.1 - 4.8e-07 29.4 0.6 0.0012 18.3 0.0 2.9 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 GBG75071.1 - 6.3e-06 26.2 0.0 0.25 11.4 0.0 4.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG75071.1 - 2.6e-05 23.8 0.0 2.8 7.7 0.1 4.8 5 0 0 5 5 5 2 PPR repeat TPR_14 PF13428.6 GBG75071.1 - 0.0072 17.1 4.0 2.5 9.2 0.0 4.9 3 0 0 3 3 3 1 Tetratricopeptide repeat UCH PF00443.29 GBG75072.1 - 4.3e-40 137.8 0.0 9.3e-40 136.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG75072.1 - 2.7e-18 66.6 0.0 1.9e-17 63.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GBG75072.1 - 3.3e-13 50.1 0.0 0.0017 18.9 0.0 3.7 3 0 0 3 3 3 3 DUSP domain ubiquitin PF00240.23 GBG75072.1 - 5e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family MCM_bind PF09739.9 GBG75072.1 - 6.2 5.1 5.1 9.6 4.5 5.1 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor TFIIF_alpha PF05793.12 GBG75073.1 - 0.52 8.8 4.2 0.71 8.4 4.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF604 PF04646.12 GBG75074.1 - 6.4e-74 248.6 0.0 1.6e-72 244.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.16 GBG75074.1 - 1.1e-13 51.3 0.0 5.8e-13 48.9 0.0 2.0 1 1 0 1 1 1 1 Fringe-like DUF659 PF04937.15 GBG75076.1 - 6.5e-17 61.8 0.6 1.1e-16 61.0 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Relaxase PF03432.14 GBG75077.1 - 0.62 9.6 7.3 0.68 9.5 5.5 1.8 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain Glyco_transf_34 PF05637.12 GBG75078.1 - 9.2e-25 87.7 0.0 2.8e-24 86.1 0.0 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family RVT_1 PF00078.27 GBG75078.1 - 2.1e-17 63.4 0.1 3.5e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nucleotid_trans PF03407.16 GBG75078.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase RVP_2 PF08284.11 GBG75078.1 - 0.14 11.9 0.0 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG75079.1 - 2.8e-29 102.2 0.1 5.4e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG75079.1 - 1.8e-09 37.5 0.0 6e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75079.1 - 7.5e-06 26.5 0.0 1.9e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75079.1 - 0.00011 22.7 0.0 0.0003 21.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG75079.1 - 0.00048 20.3 0.8 0.021 15.1 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG75079.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG75079.1 - 0.0016 17.6 3.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 Autophagy protein Apg17 TolA_bind_tri PF16331.5 GBG75079.1 - 0.0041 17.2 4.3 0.0041 17.2 4.3 1.9 2 0 0 2 2 1 1 TolA binding protein trimerisation SlyX PF04102.12 GBG75079.1 - 0.013 16.1 3.3 0.013 16.1 3.3 3.1 2 1 1 3 3 3 0 SlyX ADIP PF11559.8 GBG75079.1 - 0.02 15.0 2.9 0.044 13.9 2.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 GBG75079.1 - 0.031 14.3 0.7 0.11 12.6 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 GBG75079.1 - 0.046 11.3 2.9 0.071 10.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc29 PF17082.5 GBG75079.1 - 0.053 13.4 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Spindle Pole Component 29 MscS_porin PF12795.7 GBG75079.1 - 0.053 13.1 9.4 0.1 12.1 9.4 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain SOG2 PF10428.9 GBG75079.1 - 0.21 10.7 1.7 0.33 10.1 1.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CorA PF01544.18 GBG75079.1 - 0.22 10.8 3.3 0.86 8.9 0.6 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 GBG75079.1 - 0.28 11.2 4.7 0.84 9.7 4.7 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 GBG75079.1 - 0.31 9.9 2.9 0.36 9.7 1.2 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.12 GBG75079.1 - 0.36 9.3 2.3 0.32 9.5 1.1 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Filament PF00038.21 GBG75079.1 - 0.41 10.2 3.7 1.5 8.3 1.2 2.2 2 0 0 2 2 2 0 Intermediate filament protein Fer4_24 PF18109.1 GBG75079.1 - 0.56 10.5 1.7 1.6 9.1 0.2 2.5 3 0 0 3 3 2 0 Ferredoxin I 4Fe-4S cluster domain Tropomyosin_1 PF12718.7 GBG75079.1 - 0.92 9.7 5.5 0.41 10.8 2.2 1.9 2 0 0 2 2 2 0 Tropomyosin like BLOC1_2 PF10046.9 GBG75079.1 - 1.6 9.1 5.2 2 8.8 0.8 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HalX PF08663.10 GBG75079.1 - 5 7.5 6.1 19 5.7 0.2 3.7 3 0 0 3 3 3 0 HalX domain RVT_1 PF00078.27 GBG75080.1 - 8.2e-30 104.0 0.1 1.3e-29 103.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75080.1 - 2.4e-15 56.4 0.0 5.6e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75080.1 - 0.0056 17.0 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG75081.1 - 4.7e-18 65.3 0.1 5.7e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75081.1 - 4.7e-05 23.1 0.0 8.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG75081.1 - 0.0037 16.9 0.1 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain FMN_dh PF01070.18 GBG75082.1 - 2.6e-139 464.1 1.1 3e-139 463.9 1.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 GBG75082.1 - 8.9e-07 28.6 1.9 1.6e-06 27.7 1.9 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GBG75082.1 - 2.1e-05 23.7 3.4 2.1e-05 23.7 3.4 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 GBG75082.1 - 0.00023 20.6 1.6 0.011 15.0 0.1 3.0 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GBG75082.1 - 0.00039 19.9 1.6 0.0092 15.5 0.0 2.8 1 1 1 3 3 3 1 Histidine biosynthesis protein TMP-TENI PF02581.17 GBG75082.1 - 0.0017 17.7 0.8 0.31 10.4 0.1 2.5 2 0 0 2 2 2 2 Thiamine monophosphate synthase Glu_synthase PF01645.17 GBG75082.1 - 0.0022 17.2 0.1 0.004 16.3 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 GBG75082.1 - 0.021 14.1 0.3 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PA PF02225.22 GBG75082.1 - 0.039 14.0 2.7 0.97 9.5 0.3 3.2 2 1 1 3 3 3 0 PA domain DUF4537 PF15057.6 GBG75082.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) FlpD PF02662.16 GBG75082.1 - 0.22 11.5 1.2 20 5.2 0.0 2.8 2 1 1 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit Nop53 PF07767.11 GBG75085.1 - 0.066 12.6 23.1 0.088 12.2 23.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ESM4 PF15952.5 GBG75085.1 - 0.51 10.7 4.5 0.71 10.3 4.5 1.2 1 0 0 1 1 1 0 Enhancer of split M4 family SDA1 PF05285.12 GBG75085.1 - 0.6 9.5 25.0 0.73 9.2 25.0 1.1 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 GBG75085.1 - 1.2 8.3 5.4 1.6 7.9 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 GBG75085.1 - 1.2 7.3 27.1 1.5 6.9 27.1 1.0 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 GBG75085.1 - 1.2 9.1 36.6 1.8 8.6 36.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.15 GBG75085.1 - 1.3 7.7 8.8 2 7.1 8.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein YL1 PF05764.13 GBG75085.1 - 1.6 8.8 26.5 2.4 8.2 26.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Vfa1 PF08432.10 GBG75085.1 - 1.7 9.0 12.4 2.5 8.4 12.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.10 GBG75085.1 - 2.1 7.6 27.5 3 7.1 27.5 1.1 1 0 0 1 1 1 0 BUD22 V_ATPase_I PF01496.19 GBG75085.1 - 2.9 5.7 4.4 3.6 5.4 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LAP1C PF05609.12 GBG75085.1 - 4.7 6.2 12.6 5.9 5.9 12.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 GBG75085.1 - 5.8 4.9 12.0 7.5 4.5 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NOA36 PF06524.12 GBG75085.1 - 6 6.1 15.6 8.4 5.6 15.6 1.2 1 0 0 1 1 1 0 NOA36 protein SAP PF02037.27 GBG75086.1 - 0.0051 16.5 0.5 0.46 10.3 0.1 2.7 2 0 0 2 2 2 2 SAP domain Integrase_H2C2 PF17921.1 GBG75087.1 - 4.4e-12 45.9 0.3 4.4e-12 45.9 0.3 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG75087.1 - 0.0016 18.6 0.1 0.004 17.3 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG75087.1 - 0.0088 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG75087.1 - 0.035 14.7 0.0 0.077 13.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG75088.1 - 1.3e-26 93.5 0.2 2.3e-26 92.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75088.1 - 2.1e-25 88.6 0.0 6e-25 87.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75088.1 - 3.4e-11 43.4 0.0 7.7e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF572 PF04502.13 GBG75088.1 - 0.12 12.0 1.6 0.22 11.1 1.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1640 PF07798.11 GBG75088.1 - 1.3 9.0 6.3 15 5.6 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) FadA PF09403.10 GBG75088.1 - 5.9 7.5 10.0 15 6.2 10.0 1.7 1 0 0 1 1 1 0 Adhesion protein FadA Dak2 PF02734.17 GBG75088.1 - 6.7 6.6 7.4 0.42 10.5 1.5 1.9 2 0 0 2 2 2 0 DAK2 domain Hydrolase_6 PF13344.6 GBG75089.1 - 1.1e-35 121.8 0.0 1.8e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG75089.1 - 1.1e-13 51.1 0.0 3.4e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GBG75089.1 - 4.2e-07 30.5 0.0 0.0016 18.8 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GBG75089.1 - 9.1e-05 22.6 0.3 0.2 11.7 0.0 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 GBG75089.1 - 0.00081 19.0 0.0 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase RT_RNaseH_2 PF17919.1 GBG75090.1 - 1.2e-25 89.4 0.0 2.6e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75090.1 - 8.3e-24 83.9 0.0 1.8e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG75090.1 - 6.6e-06 26.0 0.2 1.8e-05 24.6 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle GYF_2 PF14237.6 GBG75091.1 - 7.4e-13 48.1 1.8 1e-12 47.7 0.4 2.1 2 0 0 2 2 2 1 GYF domain 2 RRM_1 PF00076.22 GBG75091.1 - 1.2e-11 44.3 0.0 3.9e-06 26.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GYF PF02213.16 GBG75091.1 - 0.0031 17.2 0.2 0.0087 15.7 0.2 1.9 1 0 0 1 1 1 1 GYF domain Inhibitor_I34 PF10466.9 GBG75091.1 - 0.2 12.3 3.1 0.83 10.3 3.1 2.0 1 0 0 1 1 1 0 Saccharopepsin inhibitor I34 RVT_1 PF00078.27 GBG75094.1 - 3.4e-33 115.0 0.1 6.3e-33 114.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75094.1 - 7.5e-29 99.7 0.0 1.8e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75094.1 - 1.3e-24 86.5 0.0 3.1e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Tom22 PF04281.13 GBG75094.1 - 0.028 14.2 0.1 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 tRNA_lig_CPD PF08302.11 GBG75094.1 - 0.028 13.9 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Sec23_helical PF04815.15 GBG75094.1 - 0.087 12.7 0.1 35 4.3 0.0 3.5 3 0 0 3 3 3 0 Sec23/Sec24 helical domain YabA PF06156.13 GBG75094.1 - 0.53 11.0 6.4 1.2 9.8 0.0 4.0 5 0 0 5 5 5 0 Initiation control protein YabA GCN5L1 PF06320.13 GBG75094.1 - 1.4 9.1 10.4 0.054 13.6 3.2 2.4 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) SAP PF02037.27 GBG75095.1 - 3.1e-10 39.6 0.1 5.8e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 SAP domain RVT_1 PF00078.27 GBG75096.1 - 5.6e-31 107.8 0.0 9.9e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75096.1 - 5.9e-31 106.5 0.0 1.2e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75096.1 - 3e-26 91.7 0.0 6.1e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG75096.1 - 0.0024 16.3 11.5 0.0043 15.4 11.5 1.4 1 0 0 1 1 1 1 CDC45-like protein DUF4820 PF16091.5 GBG75096.1 - 0.033 13.6 3.6 0.095 12.1 3.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CobT PF06213.12 GBG75096.1 - 0.043 13.2 18.2 0.097 12.1 18.2 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Merozoite_SPAM PF07133.11 GBG75096.1 - 0.14 12.1 33.4 0.23 11.4 33.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Mpp10 PF04006.12 GBG75096.1 - 0.28 9.6 21.5 0.56 8.6 21.5 1.4 1 0 0 1 1 1 0 Mpp10 protein DUF3391 PF11871.8 GBG75096.1 - 0.45 11.1 7.6 0.035 14.7 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Nop14 PF04147.12 GBG75096.1 - 0.49 8.6 23.2 1.1 7.4 23.2 1.5 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 GBG75096.1 - 0.5 10.5 3.1 0.49 10.5 0.2 2.1 2 0 0 2 2 2 0 DDHD domain DNA_pol_phi PF04931.13 GBG75096.1 - 0.58 8.2 28.6 0.88 7.6 28.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM76 PF16046.5 GBG75096.1 - 1.1 8.6 6.1 0.21 10.9 0.7 2.1 2 0 0 2 2 2 0 FAM76 protein RR_TM4-6 PF06459.12 GBG75096.1 - 1.2 8.9 14.4 3.1 7.5 14.4 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 GBG75096.1 - 1.5 7.7 23.0 2.6 6.9 23.0 1.3 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.12 GBG75096.1 - 1.5 8.1 24.0 0.14 11.5 18.6 1.8 2 0 0 2 2 2 0 SDA1 NOA36 PF06524.12 GBG75096.1 - 2.5 7.3 18.5 5.7 6.2 18.5 1.5 1 0 0 1 1 1 0 NOA36 protein DUF5523 PF17661.1 GBG75096.1 - 8.3 6.0 20.7 17 5.0 20.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) pPIWI_RE_Y PF18156.1 GBG75097.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y Spore_GerAC PF05504.11 GBG75098.1 - 0.002 18.4 0.6 7.7 6.7 0.0 3.1 3 0 0 3 3 3 3 Spore germination B3/ GerAC like, C-terminal KASH PF10541.9 GBG75099.1 - 0.15 12.3 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 Nuclear envelope localisation domain PPTA PF01239.22 GBG75100.1 - 3.2e-40 134.7 12.2 7.5e-11 41.4 0.9 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat LRR_4 PF12799.7 GBG75100.1 - 0.00086 19.6 0.6 0.00086 19.6 0.6 2.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG75100.1 - 0.0011 18.7 7.2 0.0056 16.4 7.3 2.2 1 1 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 GBG75100.1 - 0.006 16.5 1.8 15 5.9 0.0 3.8 3 0 0 3 3 3 1 Leucine Rich repeat LRR_9 PF14580.6 GBG75100.1 - 0.02 14.4 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat VIR_N PF15912.5 GBG75100.1 - 0.08 12.5 1.8 0.14 11.8 1.8 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal CAP_N PF01213.19 GBG75100.1 - 0.26 10.7 5.9 0.44 10.0 5.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GBG75100.1 - 0.58 10.2 2.5 1.3 9.1 2.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator RVT_1 PF00078.27 GBG75101.1 - 2.8e-22 79.3 0.0 4.6e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75101.1 - 1.8e-15 56.7 0.8 4.1e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG75101.1 - 6.2e-13 48.4 0.0 6.8e-12 45.1 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG75101.1 - 5.4e-11 42.7 0.0 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG75101.1 - 0.00013 22.1 0.0 0.0004 20.5 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger COPIIcoated_ERV PF07970.12 GBG75102.1 - 3.9e-43 147.9 0.1 7.3e-43 147.0 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter RVT_1 PF00078.27 GBG75102.1 - 7.6e-29 100.8 0.0 1.4e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75102.1 - 1.1e-20 73.8 0.1 3e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75102.1 - 6.8e-19 68.2 0.1 6.4e-14 52.2 0.0 3.6 3 0 0 3 3 3 2 Integrase core domain ERGIC_N PF13850.6 GBG75102.1 - 2.8e-17 62.8 0.0 6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Integrase_H2C2 PF17921.1 GBG75102.1 - 6.4e-17 61.4 0.2 1.3e-16 60.4 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG75102.1 - 7.2e-16 58.1 0.0 2.9e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG75102.1 - 0.039 13.9 1.5 0.12 12.4 1.5 1.8 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG75102.1 - 0.096 13.0 0.0 0.33 11.3 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein NSP2-B_epitope PF14757.6 GBG75103.1 - 0.035 13.8 3.8 0.019 14.7 1.4 1.6 1 1 1 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein rve PF00665.26 GBG75104.1 - 1.2e-06 28.8 0.0 2.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG75104.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain GCN5L1 PF06320.13 GBG75104.1 - 2.9 8.0 6.3 3.4 7.8 4.2 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) PRP1_N PF06424.12 GBG75105.1 - 0.0031 17.9 5.9 0.0053 17.2 5.9 1.4 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal DUF4337 PF14235.6 GBG75105.1 - 1.9 8.6 7.3 2.9 8.0 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CDC27 PF09507.10 GBG75105.1 - 2.2 7.6 13.8 3 7.1 13.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RT_RNaseH PF17917.1 GBG75107.1 - 4.3e-23 81.6 0.0 7.8e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75107.1 - 1.2e-22 79.8 0.0 2.3e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75107.1 - 8.4e-13 48.2 0.1 1.9e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG75107.1 - 6.1e-06 26.7 0.0 1.7e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG75107.1 - 0.00038 20.7 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75107.1 - 0.001 19.7 0.0 0.0026 18.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG75107.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG75107.1 - 0.027 14.3 0.1 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 Aspartyl protease SAP PF02037.27 GBG75108.1 - 2.3e-12 46.3 0.4 5.3e-12 45.2 0.4 1.7 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 GBG75108.1 - 3.3e-12 46.0 13.1 2.5e-07 30.4 2.2 4.4 2 2 2 4 4 4 4 Tho1/MOS11 C-terminal domain tRNA-synt_2 PF00152.20 GBG75109.1 - 1e-76 258.1 0.0 1.2e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GBG75109.1 - 1.5e-09 37.7 1.0 2.8e-09 36.8 1.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GBG75109.1 - 0.00097 18.7 0.2 0.68 9.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Frigida PF07899.11 GBG75110.1 - 1.2e-98 330.0 2.0 2.4e-98 329.0 0.5 2.0 2 0 0 2 2 2 1 Frigida-like protein Nnf1 PF03980.14 GBG75110.1 - 1 9.8 13.4 0.28 11.6 0.4 3.6 2 1 0 2 2 2 0 Nnf1 Imm5 PF14423.6 GBG75110.1 - 5 7.3 7.5 6.9 6.9 3.8 2.6 2 0 0 2 2 2 0 Immunity protein Imm5 HSP70 PF00012.20 GBG75111.1 - 9.4e-258 856.3 9.3 7.2e-138 460.4 0.6 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG75111.1 - 3.7e-14 52.3 0.3 1.2e-10 40.7 0.1 2.9 2 1 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GBG75111.1 - 0.00019 21.2 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 GBG75111.1 - 0.03 13.3 0.2 0.38 9.7 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain T2SSK PF03934.13 GBG75112.1 - 0.033 13.6 0.1 0.039 13.3 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Ribosomal_S7 PF00177.21 GBG75113.1 - 8e-38 129.4 2.3 1e-37 129.1 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_L6e PF01159.19 GBG75113.1 - 0.12 13.0 0.1 0.19 12.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e Spc7 PF08317.11 GBG75114.1 - 0.0045 15.9 17.5 0.0053 15.7 17.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 GBG75114.1 - 0.0066 16.4 2.9 0.0066 16.4 2.9 3.0 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 GBG75114.1 - 0.015 15.6 14.9 0.081 13.2 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Fez1 PF06818.15 GBG75114.1 - 0.016 15.7 14.5 0.045 14.2 14.2 1.7 1 1 0 1 1 1 0 Fez1 Atg14 PF10186.9 GBG75114.1 - 0.031 13.4 15.3 0.037 13.1 15.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SAM_decarbox PF01536.16 GBG75114.1 - 0.045 12.8 1.9 0.049 12.6 1.9 1.1 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase GAS PF13851.6 GBG75114.1 - 0.068 12.5 16.0 0.26 10.6 8.5 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 GBG75114.1 - 0.1 11.9 11.8 0.12 11.7 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3053 PF11254.8 GBG75114.1 - 0.12 11.9 8.2 1.5 8.3 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) Csm1_N PF18504.1 GBG75114.1 - 0.13 12.6 13.7 0.47 10.8 2.9 3.2 1 1 2 3 3 3 0 Csm1 N-terminal domain ERM PF00769.19 GBG75114.1 - 0.15 11.8 22.4 0.18 11.6 22.4 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TolA_bind_tri PF16331.5 GBG75114.1 - 0.16 12.1 12.6 0.15 12.1 0.6 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation bZIP_1 PF00170.21 GBG75114.1 - 0.2 11.8 10.6 1.2 9.2 1.0 2.6 2 1 0 2 2 2 0 bZIP transcription factor Golgin_A5 PF09787.9 GBG75114.1 - 0.29 10.6 16.8 0.44 10.0 16.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 ADIP PF11559.8 GBG75114.1 - 0.33 11.0 17.6 0.16 12.1 6.4 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 GBG75114.1 - 0.46 9.8 14.3 19 4.5 14.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Mto2_bdg PF12808.7 GBG75114.1 - 0.78 10.1 10.9 2.2 8.7 1.9 3.1 1 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Paramyxo_ncap PF00973.19 GBG75114.1 - 0.88 8.4 7.4 0.95 8.3 7.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TssO PF17561.2 GBG75114.1 - 1.1 9.4 7.7 7.3 6.7 1.1 2.8 2 1 0 3 3 3 0 Type VI secretion system, TssO Jnk-SapK_ap_N PF09744.9 GBG75114.1 - 1.6 8.9 19.1 1.6 9.0 18.2 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 YabA PF06156.13 GBG75114.1 - 1.8 9.3 11.3 1.3 9.7 2.5 2.1 1 1 1 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 GBG75114.1 - 1.8 8.6 23.0 2.2 8.4 6.1 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cgr1 PF03879.14 GBG75114.1 - 1.9 8.9 12.1 8.4 6.8 12.0 1.9 1 1 0 1 1 1 0 Cgr1 family DUF4404 PF14357.6 GBG75114.1 - 1.9 9.2 15.7 0.79 10.4 3.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) V_ATPase_I PF01496.19 GBG75114.1 - 2.7 5.8 9.1 3 5.6 9.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Plasmid_RAQPRD PF09686.10 GBG75114.1 - 3.3 8.0 10.4 0.46 10.7 1.7 3.0 1 1 2 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) YlqD PF11068.8 GBG75114.1 - 3.9 7.8 13.5 2.4 8.6 0.2 2.1 1 1 1 2 2 2 0 YlqD protein APG6_N PF17675.1 GBG75114.1 - 5.5 7.5 23.4 38 4.8 14.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4140 PF13600.6 GBG75114.1 - 6 7.4 13.8 7.1e+03 -2.5 13.8 2.8 1 1 0 1 1 0 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 GBG75114.1 - 6.3 6.6 12.1 1.8 8.4 1.6 2.6 1 1 1 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 GBG75114.1 - 6.8 6.8 15.6 20 5.3 15.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2203 PF09969.9 GBG75114.1 - 6.8 7.4 8.6 61 4.4 8.4 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CENP-H PF05837.12 GBG75114.1 - 6.9 7.1 19.2 2.8 8.4 9.3 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FlxA PF14282.6 GBG75114.1 - 7.1 6.7 17.4 68 3.5 9.4 2.3 1 1 1 2 2 2 0 FlxA-like protein LPP20 PF02169.16 GBG75114.1 - 8.9 6.7 10.4 2.3 8.6 5.7 2.1 1 1 1 2 2 2 0 LPP20 lipoprotein S-AdoMet_synt_C PF02773.16 GBG75115.1 - 1.4e-65 219.4 0.3 4.3e-65 217.9 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GBG75115.1 - 5.9e-48 162.1 0.0 1.1e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG75115.1 - 2e-43 147.1 0.6 4.1e-43 146.1 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DnaJ_CXXCXGXG PF00684.19 GBG75115.1 - 0.59 10.5 3.4 1.3 9.4 3.4 1.5 1 0 0 1 1 1 0 DnaJ central domain PHD PF00628.29 GBG75115.1 - 1.9 8.4 4.3 6.3 6.8 0.1 2.3 2 0 0 2 2 2 0 PHD-finger gag-asp_proteas PF13975.6 GBG75116.1 - 1.6e-07 31.8 0.0 3.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75116.1 - 8.6e-06 26.3 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG75116.1 - 0.00028 20.7 0.3 0.00049 19.9 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG75116.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease tRNA-synt_His PF13393.6 GBG75117.1 - 2.5e-48 165.0 0.1 4.6e-48 164.1 0.1 1.5 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Lyase_aromatic PF00221.19 GBG75117.1 - 4.6e-20 71.7 0.9 4.6e-20 71.7 0.9 2.6 2 1 1 3 3 3 2 Aromatic amino acid lyase HGTP_anticodon PF03129.20 GBG75117.1 - 1e-13 51.2 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 GBG75117.1 - 1.7e-08 34.3 0.0 2.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 GBG75117.1 - 9.8e-06 25.7 0.0 0.0001 22.3 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 GBG75117.1 - 0.0049 16.0 0.0 0.081 12.0 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 GBG75117.1 - 0.024 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Bestrophin PF01062.21 GBG75119.1 - 1.3e-20 74.0 9.6 1.9e-20 73.5 9.6 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Leu_leader PF08054.11 GBG75119.1 - 0.039 13.5 1.8 0.1 12.2 1.8 1.6 1 0 0 1 1 1 0 Leucine operon leader peptide SHE3 PF17078.5 GBG75121.1 - 0.013 15.3 10.3 0.015 15.0 10.3 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Zein-binding PF04576.15 GBG75121.1 - 0.014 15.6 18.6 0.037 14.3 17.6 2.3 1 1 0 1 1 1 0 Zein-binding Rootletin PF15035.6 GBG75121.1 - 0.029 14.4 19.7 0.084 12.9 13.2 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.11 GBG75121.1 - 0.033 13.1 17.4 0.046 12.6 17.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 GBG75121.1 - 0.035 13.6 19.0 0.04 13.4 19.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 GBG75121.1 - 0.079 12.3 10.6 0.11 11.9 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 GBG75121.1 - 0.084 12.9 23.6 0.57 10.2 4.2 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prominin PF05478.11 GBG75121.1 - 0.091 10.7 7.6 0.12 10.3 7.6 1.2 1 0 0 1 1 1 0 Prominin Curto_V2 PF07325.11 GBG75121.1 - 0.17 11.7 1.9 0.16 11.8 1.0 1.4 1 1 0 1 1 1 0 Curtovirus V2 protein HIP1_clath_bdg PF16515.5 GBG75121.1 - 0.23 12.1 25.1 0.16 12.6 12.2 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tektin PF03148.14 GBG75121.1 - 0.42 9.3 16.3 0.53 9.0 16.3 1.1 1 0 0 1 1 1 0 Tektin family Fib_alpha PF08702.10 GBG75121.1 - 0.46 10.7 10.1 0.67 10.1 10.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 GBG75121.1 - 0.52 10.4 16.8 0.65 10.1 16.4 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Rab5-bind PF09311.11 GBG75121.1 - 0.54 9.6 20.8 1.2 8.4 19.3 1.8 1 1 1 2 2 2 0 Rabaptin-like protein HalX PF08663.10 GBG75121.1 - 0.61 10.4 13.3 0.51 10.7 3.9 2.8 3 0 0 3 3 3 0 HalX domain FUSC PF04632.12 GBG75121.1 - 0.62 8.5 7.2 0.68 8.4 7.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fzo_mitofusin PF04799.13 GBG75121.1 - 0.74 9.3 13.3 2.5 7.7 3.8 2.1 1 1 1 2 2 2 0 fzo-like conserved region OmpH PF03938.14 GBG75121.1 - 0.78 10.1 24.5 0.037 14.3 12.8 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) BST2 PF16716.5 GBG75121.1 - 0.89 10.2 21.1 0.23 12.1 11.6 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Exonuc_VII_L PF02601.15 GBG75121.1 - 1.2 8.7 10.6 1.6 8.3 10.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_MT_bd PF06657.13 GBG75121.1 - 1.2 9.6 20.5 4.4 7.8 0.8 3.1 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Jnk-SapK_ap_N PF09744.9 GBG75121.1 - 1.4 9.1 22.1 0.27 11.5 9.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 GBG75121.1 - 1.6 9.0 17.9 1.3 9.3 10.0 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 GBG75121.1 - 1.7 9.2 7.1 2.9 8.4 0.2 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Cut12 PF11500.8 GBG75121.1 - 1.8 8.5 15.7 0.86 9.6 4.4 2.3 1 1 1 2 2 2 0 Spindle pole body formation-associated protein GAS PF13851.6 GBG75121.1 - 2.8 7.2 21.6 24 4.2 21.8 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 GBG75121.1 - 3.7 6.3 18.2 5.1 5.9 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 GBG75121.1 - 4.8 7.2 13.1 5.7 7.0 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 GBG75121.1 - 5 7.5 12.8 7.3 6.9 1.4 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein TPR_MLP1_2 PF07926.12 GBG75121.1 - 5.5 7.1 24.7 5.7 7.0 10.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PRKCSH-like PF12999.7 GBG75121.1 - 7.2 6.4 8.6 1 9.1 2.6 2.0 1 1 1 2 2 2 0 Glucosidase II beta subunit-like Atg14 PF10186.9 GBG75121.1 - 8.4 5.4 18.4 23 4.0 18.4 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 GBG75121.1 - 8.5 7.1 14.1 4.5 8.0 6.0 2.8 1 1 2 3 3 3 0 Initiation control protein YabA RT_RNaseH_2 PF17919.1 GBG75122.1 - 7e-30 103.0 0.0 1.6e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75122.1 - 1e-26 93.2 0.5 2.8e-26 91.8 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75122.1 - 5.1e-18 64.9 0.2 1.1e-17 63.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75122.1 - 8.6e-15 55.0 0.0 3e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DUF659 PF04937.15 GBG75123.1 - 1e-40 139.1 0.0 1.9e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG75123.1 - 6e-07 29.2 1.5 1.7e-06 27.7 1.5 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FAM184 PF15665.5 GBG75124.1 - 4e-10 39.8 12.3 4e-10 39.8 12.3 2.3 2 0 0 2 2 2 1 Family with sequence similarity 184, A and B Retrotrans_gag PF03732.17 GBG75124.1 - 1.8 8.9 6.3 4.3 7.7 0.1 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein Exonuc_VII_L PF02601.15 GBG75124.1 - 2 7.9 11.8 5.1 6.6 1.0 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Thioredoxin PF00085.20 GBG75125.1 - 2.7e-15 56.2 0.0 4.1e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GBG75125.1 - 0.00087 19.6 0.0 0.0017 18.7 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin-like T4_deiodinase PF00837.17 GBG75125.1 - 0.0013 18.0 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase Thioredoxin_7 PF13899.6 GBG75125.1 - 0.017 15.3 0.3 0.05 13.8 0.3 1.8 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 GBG75125.1 - 0.025 15.0 0.2 0.97 9.9 0.2 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.21 GBG75125.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family zf-met PF12874.7 GBG75126.1 - 6.9e-10 39.0 12.8 2.3e-06 27.8 1.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GBG75126.1 - 2.5e-07 30.8 8.5 0.00053 20.2 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-SCNM1 PF15803.5 GBG75126.1 - 0.035 13.7 4.4 3.2 7.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 zf-C2H2_2 PF12756.7 GBG75126.1 - 0.12 12.8 5.2 0.16 12.3 0.9 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ribosomal_S10 PF00338.22 GBG75127.1 - 1.8e-33 114.7 0.0 2.6e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e RT_RNaseH_2 PF17919.1 GBG75129.1 - 3.6e-27 94.3 0.0 1.2e-26 92.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75129.1 - 3.8e-24 85.0 0.0 1e-23 83.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MORN PF02493.20 GBG75131.1 - 5.9e-30 101.4 43.0 9.1e-06 25.3 0.4 7.1 7 0 0 7 7 7 6 MORN repeat DUF445 PF04286.12 GBG75131.1 - 0.00029 20.7 6.6 0.00043 20.2 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Ribosomal_L11_N PF03946.14 GBG75131.1 - 0.013 15.3 2.0 4 7.4 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain DUF3646 PF12362.8 GBG75131.1 - 2.9 8.3 4.7 1e+02 3.2 1.2 3.9 2 1 1 3 3 3 0 DNA polymerase III gamma and tau subunits C terminal Ax_dynein_light PF10211.9 GBG75132.1 - 6.8e-52 176.1 15.6 5.9e-32 111.1 10.3 3.1 2 1 1 3 3 3 2 Axonemal dynein light chain DivIC PF04977.15 GBG75132.1 - 0.0065 16.2 1.1 0.0065 16.2 1.1 3.5 4 1 1 5 5 5 1 Septum formation initiator DUF4164 PF13747.6 GBG75132.1 - 0.25 11.6 11.7 5.2 7.4 6.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Integrase_H2C2 PF17921.1 GBG75133.1 - 6.3e-14 51.8 0.3 1.6e-13 50.5 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG75133.1 - 7.2e-08 32.9 0.0 1.6e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75133.1 - 2.1e-06 28.3 0.0 4.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG75133.1 - 3e-06 26.9 0.0 4.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75133.1 - 0.0005 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75133.1 - 0.0045 17.2 0.0 0.0094 16.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG75133.1 - 0.0082 15.9 0.2 0.024 14.4 0.1 1.7 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 GBG75133.1 - 0.0088 16.1 0.5 0.025 14.7 0.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 GBG75133.1 - 0.031 14.5 0.7 0.088 13.1 0.7 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 GBG75133.1 - 0.038 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG75134.1 - 6.5e-06 26.4 0.6 1.2e-05 25.6 0.6 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG75134.1 - 0.06 13.4 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DnaJ PF00226.31 GBG75135.1 - 0.00099 19.2 0.0 0.0032 17.6 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain Glyco_hydro_108 PF05838.12 GBG75135.1 - 0.013 15.9 0.1 0.073 13.5 0.1 2.3 1 0 0 1 1 1 0 Glycosyl hydrolase 108 CCDC71L PF15374.6 GBG75135.1 - 9.1 5.4 10.2 21 4.2 10.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Peptidase_M76 PF09768.9 GBG75136.1 - 0.0066 16.2 0.4 0.0098 15.7 0.4 1.2 1 0 0 1 1 1 1 Peptidase M76 family BUD22 PF09073.10 GBG75136.1 - 0.46 9.8 17.9 0.54 9.5 17.9 1.1 1 0 0 1 1 1 0 BUD22 ORC_WH_C PF18137.1 GBG75136.1 - 1.8 8.7 7.1 3 7.9 7.1 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Nop14 PF04147.12 GBG75136.1 - 2.2 6.4 18.8 2.7 6.1 18.8 1.0 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG75136.1 - 2.4 6.8 5.2 2.9 6.6 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 GBG75136.1 - 4 6.8 19.1 4.9 6.5 19.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG75136.1 - 4.9 5.3 14.0 4.1 5.6 12.7 1.5 2 0 0 2 2 2 0 CDC45-like protein DUF4746 PF15928.5 GBG75136.1 - 5.4 6.3 13.9 7.3 5.9 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RVP_2 PF08284.11 GBG75137.1 - 0.0094 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG75137.1 - 0.15 11.8 0.2 0.31 10.7 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVT_1 PF00078.27 GBG75138.1 - 4.4e-30 104.8 3.3 6.3e-30 104.3 0.0 2.6 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75138.1 - 1.2e-24 86.2 0.0 3e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75138.1 - 2.4e-24 85.6 0.0 4.5e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG75138.1 - 5.1e-08 33.4 0.0 1.6e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG75138.1 - 2.1e-07 30.8 0.0 7.9e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG75138.1 - 3.1e-06 27.6 0.0 7.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG75138.1 - 0.0019 18.4 1.3 0.0084 16.4 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG75138.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG75138.1 - 0.022 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 RVP PF00077.20 GBG75138.1 - 0.15 12.3 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RcpC PF16976.5 GBG75138.1 - 0.2 11.7 0.2 0.4 10.7 0.2 1.4 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB DUF4187 PF13821.6 GBG75138.1 - 0.28 11.0 6.2 0.037 13.8 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) AMP-binding PF00501.28 GBG75139.1 - 1e-86 291.2 0.0 1.4e-86 290.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GBG75139.1 - 5.7e-23 80.6 2.3 1.5e-22 79.3 2.3 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 GBG75139.1 - 5.9e-21 75.2 0.0 1.3e-20 74.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1932 PF09130.11 GBG75140.1 - 0.12 12.4 1.4 0.27 11.3 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1932) ABC_tran PF00005.27 GBG75141.1 - 3.4e-22 79.4 0.0 6.7e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG75141.1 - 8.5e-16 58.0 17.6 1.9e-15 56.8 17.6 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG75141.1 - 5.5e-08 33.0 0.0 4.7e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 GBG75141.1 - 0.005 17.5 0.0 0.0098 16.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 GBG75141.1 - 0.13 11.7 0.1 2.3 7.6 0.0 2.0 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain LRR_4 PF12799.7 GBG75142.1 - 3.3e-12 46.4 12.4 1.3e-06 28.7 0.8 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG75142.1 - 3.3e-11 42.8 16.9 4.1e-07 29.7 2.8 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 GBG75142.1 - 4.6e-08 32.5 11.9 0.32 11.7 0.0 5.2 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_6 PF13516.6 GBG75142.1 - 1.8e-06 27.5 7.0 0.92 9.7 0.3 4.3 4 0 0 4 4 4 3 Leucine Rich repeat LRRNT_2 PF08263.12 GBG75142.1 - 0.0073 16.6 0.4 0.019 15.2 0.4 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain GIY-YIG PF01541.24 GBG75143.1 - 0.047 14.0 0.2 0.15 12.4 0.0 2.0 1 1 1 2 2 2 0 GIY-YIG catalytic domain Pkinase PF00069.25 GBG75144.1 - 5.2e-49 167.0 0.0 6.5e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG75144.1 - 2.9e-40 138.2 0.0 6.1e-40 137.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG75144.1 - 0.035 14.0 0.7 0.23 11.3 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Telomere_res PF16684.5 GBG75144.1 - 0.095 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Telomere resolvase Pkinase_fungal PF17667.1 GBG75144.1 - 0.2 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ASF1_hist_chap PF04729.13 GBG75145.1 - 2.8e-55 186.5 0.2 3.8e-55 186.1 0.2 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RT_RNaseH PF17917.1 GBG75146.1 - 2e-23 82.7 0.0 4.5e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75146.1 - 3.2e-13 49.6 0.0 6.2e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG75146.1 - 2.2e-08 33.8 1.2 4.1e-08 32.9 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG75146.1 - 0.024 14.5 2.7 0.044 13.6 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Zip PF02535.22 GBG75147.1 - 5.5e-32 111.3 3.8 1e-31 110.4 3.8 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter CHS5_N PF16892.5 GBG75147.1 - 0.045 13.7 2.3 0.077 13.0 0.6 2.3 3 0 0 3 3 3 0 Chitin biosynthesis protein CHS5 N-terminus Wzy_C PF04932.15 GBG75147.1 - 0.11 12.2 3.4 0.19 11.3 0.0 2.4 2 0 0 2 2 2 0 O-Antigen ligase TGT PF01702.18 GBG75148.1 - 8.3e-107 357.4 1.0 5.8e-102 341.4 0.3 3.2 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase Biotin_carb_N PF00289.22 GBG75149.1 - 0.42 11.2 6.2 0.54 10.8 5.8 1.5 1 1 0 1 1 1 0 Biotin carboxylase, N-terminal domain HC2 PF07382.11 GBG75149.1 - 9.7 6.2 25.6 14 5.7 25.6 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DDHD PF02862.17 GBG75150.1 - 1.7e-25 90.5 0.9 1.3e-20 74.5 0.0 9.4 6 4 1 7 7 7 2 DDHD domain DUF1652 PF07865.11 GBG75150.1 - 1.9 8.4 5.4 26 4.7 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) UCH PF00443.29 GBG75151.1 - 3.1e-25 89.1 0.0 4.3e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG75151.1 - 1.7e-05 24.6 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase BUD22 PF09073.10 GBG75151.1 - 0.092 12.1 26.9 1.3 8.3 0.5 2.3 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 GBG75151.1 - 0.14 11.6 29.8 0.33 10.3 1.4 2.6 2 0 0 2 2 2 0 SDA1 DUF1738 PF08401.11 GBG75151.1 - 2.3 8.3 7.7 16 5.6 2.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) RPN2_C PF18004.1 GBG75151.1 - 2.6 8.0 16.5 5.7 6.8 0.6 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CPSF100_C PF13299.6 GBG75151.1 - 3.1 7.9 10.0 11 6.2 0.4 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 GBG75151.1 - 8.2 5.7 6.6 1.7 8.0 1.7 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SURF2 PF05477.11 GBG75151.1 - 8.6 6.0 15.7 5.6 6.6 6.8 2.4 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Connexin PF00029.19 GBG75151.1 - 9 6.0 6.0 42 3.8 2.8 2.1 2 0 0 2 2 2 0 Connexin DUF719 PF05334.13 GBG75151.1 - 9.3 6.4 9.7 2.7 8.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) LUC7 PF03194.15 GBG75153.1 - 1.1e-68 231.6 8.7 5.7e-68 229.3 8.7 2.0 1 1 0 1 1 1 1 LUC7 N_terminus Rpr2 PF04032.16 GBG75153.1 - 0.0066 16.7 0.1 0.034 14.4 0.0 2.2 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Protein_K PF12283.8 GBG75153.1 - 0.36 11.1 1.7 4.5 7.6 0.5 2.4 2 0 0 2 2 2 0 Bacteriophage protein K DUF2203 PF09969.9 GBG75153.1 - 0.39 11.5 6.6 1.1 10.1 0.5 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ran-binding PF05508.11 GBG75153.1 - 0.62 9.0 3.1 0.23 10.4 0.5 1.5 2 0 0 2 2 2 0 RanGTP-binding protein ZapB PF06005.12 GBG75153.1 - 1.9 9.0 9.2 3.2 8.3 1.2 2.8 2 0 0 2 2 2 0 Cell division protein ZapB DUF3460 PF11943.8 GBG75153.1 - 3.7 7.9 10.9 3.7 7.9 0.3 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3460) RRM_1 PF00076.22 GBG75154.1 - 2.8e-20 71.9 1.1 3.2e-10 39.7 0.1 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG75154.1 - 6.5e-08 32.6 0.0 0.022 14.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 GBG75154.1 - 0.14 12.0 0.0 6.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Ribosomal_L7Ae PF01248.26 GBG75155.1 - 9.2e-24 83.0 0.4 1.6e-23 82.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 GBG75155.1 - 0.078 12.0 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) RVT_1 PF00078.27 GBG75156.1 - 5.3e-27 94.8 0.1 9.5e-27 93.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75156.1 - 1.4e-11 44.3 0.0 2.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75156.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Hormone_3 PF00159.18 GBG75156.1 - 0.067 13.3 2.2 0.15 12.2 0.7 2.5 2 0 0 2 2 2 0 Pancreatic hormone peptide ActA PF05058.12 GBG75156.1 - 0.66 8.3 2.4 1 7.6 2.4 1.2 1 0 0 1 1 1 0 ActA Protein Histone PF00125.24 GBG75157.1 - 4.8e-19 69.0 0.0 6.4e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 GBG75157.1 - 2.2e-11 43.3 0.4 2.2e-11 43.3 0.4 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 GBG75157.1 - 0.00022 21.4 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RVP_2 PF08284.11 GBG75158.1 - 0.018 14.8 0.0 0.048 13.4 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF4392 PF14336.6 GBG75158.1 - 0.12 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) YidD PF01809.18 GBG75159.1 - 2.5e-24 84.9 1.2 3.9e-24 84.3 1.2 1.3 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor AC_N PF16214.5 GBG75159.1 - 5.1 6.1 7.0 9.9 5.2 6.9 1.6 1 1 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region YidD PF01809.18 GBG75160.1 - 3.8e-05 23.5 0.1 6.7e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor AC_N PF16214.5 GBG75160.1 - 0.24 10.5 2.1 0.49 9.5 2.1 1.6 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region RVT_1 PF00078.27 GBG75161.1 - 9.3e-28 97.2 0.0 1.6e-26 93.2 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75161.1 - 2.1e-24 85.5 0.0 6.1e-24 84.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75161.1 - 8.9e-22 77.4 0.0 2.9e-21 75.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG75161.1 - 4.9e-07 30.2 0.0 1.3e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75161.1 - 5.7e-07 30.1 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG75161.1 - 5.4e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75161.1 - 6.3e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG75161.1 - 0.0006 20.0 9.2 0.0008 19.6 0.0 3.9 4 0 0 4 4 4 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG75163.1 - 7.8e-17 61.5 0.1 1.6e-16 60.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG75163.1 - 2.3e-09 37.1 0.0 5.9e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75163.1 - 3.4e-09 37.2 0.0 1.6e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75163.1 - 7.3e-08 32.9 0.1 1.1e-06 29.1 0.0 2.9 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG75163.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease WTX PF09422.10 GBG75163.1 - 0.009 15.1 1.0 0.016 14.3 1.0 1.3 1 0 0 1 1 1 1 WTX protein V_ATPase_I PF01496.19 GBG75164.1 - 0.32 8.9 11.5 0.31 8.9 11.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.19 GBG75164.1 - 0.8 9.5 27.1 1.1 9.0 27.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Ribosomal_L1 PF00687.21 GBG75167.1 - 0.0001 22.1 0.2 0.00017 21.4 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family RNA_pol_Rpb4 PF03874.16 GBG75168.1 - 0.32 11.3 1.2 0.51 10.7 1.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 RVP_2 PF08284.11 GBG75169.1 - 1.3e-09 38.0 0.0 3.4e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75169.1 - 2.9e-08 34.2 0.0 7.2e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75169.1 - 2.4e-06 28.0 0.0 7.2e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG75169.1 - 0.0044 17.3 0.1 0.0044 17.3 0.1 3.0 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG75169.1 - 0.005 16.6 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF4677 PF15726.5 GBG75169.1 - 0.13 12.5 0.4 0.32 11.1 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) RNA_pol_Rpb4 PF03874.16 GBG75170.1 - 1.4e-08 35.1 0.0 2.2e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 Sterol_MT_C PF08498.10 GBG75170.1 - 0.15 12.4 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal DNA_pack_N PF02500.15 GBG75171.1 - 0.05 13.4 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Gp58 PF07902.11 GBG75171.1 - 0.14 10.4 0.3 0.28 9.4 0.3 1.4 1 1 0 1 1 1 0 gp58-like protein Cation_ATPase_C PF00689.21 GBG75171.1 - 0.29 10.8 0.7 0.43 10.3 0.7 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus RVT_1 PF00078.27 GBG75172.1 - 3e-64 216.6 1.9 9.7e-25 87.4 0.0 3.8 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75172.1 - 3.5e-44 148.9 0.0 3.3e-24 84.8 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase E1-E2_ATPase PF00122.20 GBG75172.1 - 8.1e-41 139.5 7.0 2e-39 135.0 1.6 3.5 3 0 0 3 3 3 1 E1-E2 ATPase rve PF00665.26 GBG75172.1 - 6.4e-29 100.6 0.1 3.9e-13 49.6 0.0 3.4 2 0 0 2 2 2 2 Integrase core domain Cation_ATPase_C PF00689.21 GBG75172.1 - 9.6e-27 93.9 2.7 9.2e-13 48.3 0.7 2.5 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GBG75172.1 - 4.3e-22 78.0 0.1 1.3e-21 76.4 0.0 1.9 2 0 0 2 2 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GBG75172.1 - 1.1e-20 74.9 0.0 4.8e-17 62.9 0.0 3.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase RT_RNaseH PF17917.1 GBG75172.1 - 1.2e-19 70.5 0.0 5.2e-11 42.8 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75172.1 - 8.6e-15 54.6 0.0 2.1e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG75172.1 - 5.7e-08 33.3 0.1 2.1e-07 31.5 0.0 2.0 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75172.1 - 1.1e-07 32.3 0.0 4.4e-07 30.4 0.0 2.1 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Hydrolase_3 PF08282.12 GBG75172.1 - 5.1e-07 29.7 3.4 5.4e-06 26.3 2.9 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RVP_2 PF08284.11 GBG75172.1 - 2.1e-06 27.6 0.0 4.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Cation_ATPase_N PF00690.26 GBG75172.1 - 7.7e-05 22.3 1.6 7.9e-05 22.3 0.0 1.9 2 0 0 2 2 1 1 Cation transporter/ATPase, N-terminus Asp_protease PF09668.10 GBG75172.1 - 0.00034 20.4 0.0 0.002 17.9 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease HAD PF12710.7 GBG75172.1 - 0.00072 20.0 0.0 0.0053 17.2 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Retrotrans_gag PF03732.17 GBG75172.1 - 0.079 13.2 6.0 0.17 12.2 0.3 3.1 3 0 0 3 3 2 0 Retrotransposon gag protein rve_3 PF13683.6 GBG75172.1 - 0.12 12.2 0.5 9.9 6.0 0.1 2.8 2 0 0 2 2 2 0 Integrase core domain AC_N PF16214.5 GBG75172.1 - 0.28 10.3 1.9 0.76 8.8 1.9 1.6 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region RVT_1 PF00078.27 GBG75174.1 - 4.5e-29 101.6 0.1 7.7e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75174.1 - 3.1e-24 85.3 0.0 6.4e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75174.1 - 1.7e-21 76.1 0.0 3.4e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG75174.1 - 3.6e-19 69.0 0.0 8.5e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Integrase_H2C2 PF17921.1 GBG75174.1 - 2.2e-18 66.1 1.0 7e-18 64.5 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG75174.1 - 4.5e-07 30.1 0.0 1.9e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Plant_tran PF04827.14 GBG75174.1 - 2e-06 27.6 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein RAP1 PF07218.11 GBG75175.1 - 0.2 9.9 4.9 0.25 9.6 4.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Histone PF00125.24 GBG75176.1 - 3.5e-20 72.7 0.5 3.5e-20 72.7 0.5 2.3 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF659 PF04937.15 GBG75178.1 - 1.1e-11 44.8 0.1 2.1e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG75178.1 - 4.6e-05 23.1 0.1 0.00013 21.7 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG75179.1 - 3.6e-32 111.3 0.1 7.1e-32 110.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PRD PF00874.20 GBG75181.1 - 0.015 15.6 0.1 0.028 14.7 0.1 1.3 1 0 0 1 1 1 0 PRD domain RuBisCO_small PF00101.20 GBG75182.1 - 1.4e-11 44.2 0.0 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain NPF PF16601.5 GBG75182.1 - 0.079 13.4 0.0 0.096 13.1 0.0 1.1 1 0 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif RuBisCO_small PF00101.20 GBG75183.1 - 6.7e-33 112.6 0.1 1.5e-32 111.5 0.1 1.5 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain DUF3367 PF11847.8 GBG75183.1 - 0.0093 13.9 0.1 0.014 13.3 0.1 1.2 1 0 0 1 1 1 1 Alpha-(1->3)-arabinofuranosyltransferase Macoilin PF09726.9 GBG75183.1 - 1.1 7.7 9.5 1.9 7.0 9.5 1.3 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 GBG75183.1 - 2.8 6.1 17.9 4 5.6 17.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG75183.1 - 6.1 4.9 22.2 8.9 4.4 22.2 1.3 1 0 0 1 1 1 0 Nop14-like family AUX_IAA PF02309.16 GBG75184.1 - 1.5e-26 93.7 0.0 1.8e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 AUX/IAA family DUF4813 PF16072.5 GBG75184.1 - 0.042 13.5 0.4 0.042 13.5 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) RT_RNaseH_2 PF17919.1 GBG75185.1 - 1.9e-19 69.5 0.0 4e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75185.1 - 3.7e-19 68.9 0.0 7.8e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75185.1 - 3.2e-14 52.8 0.1 8.9e-14 51.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75185.1 - 6.7e-10 39.2 0.0 3.3e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG75185.1 - 3.5e-08 33.2 0.0 6.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG75185.1 - 2.1e-07 31.4 0.0 4.8e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75185.1 - 5.2e-06 27.0 0.0 1.1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG75185.1 - 0.0014 18.8 0.1 0.0034 17.6 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG75185.1 - 0.012 15.5 0.5 0.024 14.4 0.5 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG75185.1 - 0.021 15.1 0.0 0.054 13.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease FAM176 PF14851.6 GBG75185.1 - 5 6.8 5.9 14 5.3 5.9 1.7 1 0 0 1 1 1 0 FAM176 family Integrase_H2C2 PF17921.1 GBG75186.1 - 1.9e-14 53.5 0.2 4e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG75186.1 - 5.2e-07 30.1 0.3 3.3e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG75186.1 - 3.7e-06 27.1 0.0 8.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG75186.1 - 0.001 19.2 0.2 0.0031 17.7 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG75186.1 - 0.0022 18.6 1.4 0.0081 16.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG75186.1 - 0.11 12.2 0.7 0.21 11.4 0.7 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG75187.1 - 1.6e-28 99.8 0.1 2.2e-28 99.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG75187.1 - 3.9e-08 33.8 0.0 8.1e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75187.1 - 5.9e-08 33.3 0.0 1.3e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG75187.1 - 1.8e-06 27.7 0.0 3.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG75187.1 - 6e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Trypsin_2 PF13365.6 GBG75188.1 - 5.1e-31 108.6 1.7 1.4e-30 107.2 0.3 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 GBG75188.1 - 3.5e-15 56.1 0.1 8.7e-15 54.8 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GBG75188.1 - 2e-10 40.4 0.3 6.1e-10 38.8 0.3 1.9 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 GBG75188.1 - 1.2e-09 38.3 0.0 2.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin PDZ PF00595.24 GBG75188.1 - 1.1e-06 28.8 0.2 4.5e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 GBG75188.1 - 0.016 15.5 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain EssA PF10661.9 GBG75189.1 - 0.11 12.3 1.2 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA gag-asp_proteas PF13975.6 GBG75190.1 - 5.9e-08 33.2 1.1 1.4e-07 31.9 0.1 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75190.1 - 4.4e-07 30.5 0.1 1.3e-06 28.9 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG75190.1 - 0.00033 20.4 0.1 0.00065 19.5 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75190.1 - 0.00054 19.8 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RskA PF10099.9 GBG75190.1 - 0.0072 16.6 0.4 0.26 11.6 0.5 2.4 2 0 0 2 2 2 1 Anti-sigma-K factor rskA zf-CCHC_3 PF13917.6 GBG75193.1 - 0.013 15.5 2.0 0.026 14.5 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle DBINO PF13892.6 GBG75193.1 - 0.35 11.2 13.6 0.51 10.7 7.5 2.8 2 0 0 2 2 2 0 DNA-binding domain zf-CCHC PF00098.23 GBG75193.1 - 1.5 9.0 4.9 2.6 8.3 4.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Mito_carr PF00153.27 GBG75194.1 - 6.7e-41 138.1 0.1 8.1e-16 57.7 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GBG75194.1 - 2e-10 41.0 0.1 0.00065 20.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG75194.1 - 3.7e-08 32.4 0.1 0.0083 15.6 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GBG75194.1 - 5.7e-08 32.1 0.0 0.018 15.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain DUF2666 PF10869.8 GBG75194.1 - 0.00055 20.2 0.0 0.38 11.0 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2666) EF-hand_5 PF13202.6 GBG75194.1 - 0.019 14.5 0.1 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 GBG75194.1 - 0.027 14.3 0.0 3.8 7.4 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair EspB PF05802.11 GBG75194.1 - 0.16 11.9 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein GIY-YIG PF01541.24 GBG75195.1 - 0.00029 21.0 1.2 0.0011 19.1 0.0 2.6 3 0 0 3 3 3 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG75195.1 - 0.031 14.4 0.2 0.067 13.3 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1178 PF06676.11 GBG75195.1 - 9.8 6.5 9.9 10 6.5 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) RVP_2 PF08284.11 GBG75196.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75196.1 - 0.0071 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A3 PF02160.15 GBG75196.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Topo_Zn_Ribbon PF08272.11 GBG75196.1 - 0.028 14.1 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease_2 PF13650.6 GBG75196.1 - 0.085 13.5 0.0 0.27 11.9 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease ox_reductase_C PF08635.10 GBG75198.1 - 0.0072 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain ArAE_2_N PF10337.9 GBG75198.1 - 0.2 10.6 2.0 0.31 10.0 2.0 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF4337 PF14235.6 GBG75198.1 - 4.3 7.4 10.5 11 6.1 10.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GTA_holin_3TM PF11351.8 GBG75198.1 - 5.9 7.5 5.3 11 6.5 5.3 1.5 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release CDC45 PF02724.14 GBG75200.1 - 0.063 11.6 13.6 0.089 11.1 13.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG75200.1 - 0.84 9.0 21.2 1.3 8.4 21.2 1.2 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 GBG75200.1 - 1.6 7.1 20.7 2.4 6.5 20.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG75200.1 - 5.7 5.0 26.9 9 4.4 26.9 1.2 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG75202.1 - 1e-24 86.4 0.0 1.7e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75202.1 - 3e-21 75.7 0.0 4.8e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75202.1 - 4e-14 52.7 0.1 5.3e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG75202.1 - 0.23 9.6 17.9 0.3 9.2 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family Porph_ging PF09697.10 GBG75202.1 - 0.64 10.6 11.1 2.3 8.8 11.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (Porph_ging) DNA_pol_phi PF04931.13 GBG75202.1 - 1.3 7.1 21.8 1.8 6.6 21.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Afi1 PF07792.12 GBG75202.1 - 1.3 9.5 5.2 2.3 8.7 5.2 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking BUD22 PF09073.10 GBG75202.1 - 1.5 8.0 13.2 2.1 7.6 13.2 1.1 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 GBG75202.1 - 1.9 8.3 10.9 2.8 7.7 10.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG75202.1 - 4.6 5.9 4.6 6.5 5.4 4.6 1.1 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG75204.1 - 1.2e-23 83.0 0.1 2.3e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75204.1 - 4.9e-11 42.8 0.2 1e-10 41.8 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG75204.1 - 5.6e-08 32.5 1.2 1.2e-07 31.5 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG75204.1 - 0.026 14.4 1.6 0.063 13.1 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG75205.1 - 3.4e-32 111.8 0.0 4.9e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Amino_oxidase PF01593.24 GBG75206.1 - 1.3e-99 334.5 0.0 1.7e-99 334.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG75206.1 - 5e-11 42.7 0.8 1.5e-10 41.2 0.8 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 GBG75206.1 - 2.2e-09 37.5 0.0 4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Pyr_redox_2 PF07992.14 GBG75206.1 - 9.1e-06 25.1 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG75206.1 - 0.00031 21.2 0.5 0.0016 19.0 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG75206.1 - 0.00062 18.6 0.1 0.0011 17.8 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 GBG75206.1 - 0.001 18.3 0.3 0.001 18.3 0.3 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 GBG75206.1 - 0.0017 17.7 0.6 0.0029 16.9 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 GBG75206.1 - 0.002 17.5 0.4 0.0052 16.1 0.4 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GBG75206.1 - 0.0033 16.8 5.6 0.0065 15.9 5.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GBG75206.1 - 0.014 14.5 0.6 0.021 13.9 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GBG75206.1 - 0.017 14.2 0.3 0.031 13.3 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Nucleoporin2 PF04096.14 GBG75208.1 - 1.1e-42 145.6 0.0 1.7e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Prefoldin PF02996.17 GBG75208.1 - 1.7e-23 82.8 0.1 2.5e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit BRE1 PF08647.11 GBG75208.1 - 0.19 11.8 0.3 0.42 10.7 0.3 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase gag-asp_proteas PF13975.6 GBG75209.1 - 1.4e-08 35.2 0.0 3.5e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75209.1 - 2.7e-06 27.9 0.0 8.3e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG75209.1 - 7.9e-05 22.6 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75209.1 - 0.00084 19.6 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG75209.1 - 0.0014 18.4 1.0 0.0024 17.7 0.2 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG75209.1 - 0.0042 17.4 0.0 0.0097 16.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG75209.1 - 0.0046 17.0 1.2 0.013 15.5 1.2 1.8 1 0 0 1 1 1 1 Zinc knuckle Itfg2 PF15907.5 GBG75210.1 - 0.01 14.9 0.4 4.3 6.3 0.0 2.5 2 0 0 2 2 2 2 Integrin-alpha FG-GAP repeat-containing protein 2 Nucleoporin2 PF04096.14 GBG75211.1 - 1.9e-44 151.4 0.0 2.9e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase SUIM_assoc PF16619.5 GBG75211.1 - 1.2 9.2 9.6 7.6 6.7 9.6 2.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GBG75211.1 - 1.5 8.4 5.3 2.7 7.5 5.3 1.3 1 0 0 1 1 1 0 Spt20 family Nucleoporin_FG PF13634.6 GBG75211.1 - 8.7 7.3 212.1 17 6.3 30.1 8.9 3 2 4 7 7 7 0 Nucleoporin FG repeat region CRF-BP PF05428.11 GBG75212.1 - 0.033 13.0 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Peptidase_C50 PF03568.17 GBG75213.1 - 0.00055 19.2 0.0 0.0012 18.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 Hid1 PF12722.7 GBG75213.1 - 1.3 7.1 0.0 1.3 7.1 0.0 4.6 7 0 0 7 7 7 0 High-temperature-induced dauer-formation protein Na_H_Exchanger PF00999.21 GBG75214.1 - 6.1e-49 166.8 31.9 7.9e-49 166.4 31.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 GBG75214.1 - 1.1e-07 32.4 0.0 0.093 13.2 0.0 3.4 3 0 0 3 3 3 3 Universal stress protein family Glyco_hydro_9 PF00759.19 GBG75217.1 - 6.8e-140 467.1 1.1 8.6e-140 466.8 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DDE_Tnp_4 PF13359.6 GBG75218.1 - 2.3e-28 98.8 0.0 5.6e-28 97.6 0.0 1.7 2 0 0 2 2 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75218.1 - 1.2e-11 44.6 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Nop14 PF04147.12 GBG75218.1 - 0.00047 18.5 25.1 0.00063 18.1 25.1 1.1 1 0 0 1 1 1 1 Nop14-like family Tim54 PF11711.8 GBG75218.1 - 0.0018 17.2 0.2 0.0026 16.6 0.2 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SDA1 PF05285.12 GBG75218.1 - 0.0033 16.9 23.0 0.0055 16.2 23.0 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG75218.1 - 0.0048 15.3 17.0 0.0066 14.8 17.0 1.1 1 0 0 1 1 1 1 CDC45-like protein DDE_Tnp_1_2 PF13586.6 GBG75218.1 - 0.0055 17.1 0.4 0.083 13.3 0.0 2.4 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG75218.1 - 0.0057 16.3 0.6 1.1 8.9 0.3 2.6 3 0 0 3 3 3 1 Transposase DDE domain V_ATPase_I PF01496.19 GBG75218.1 - 0.064 11.2 4.5 0.092 10.7 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2722 PF10846.8 GBG75218.1 - 0.085 11.8 13.5 0.12 11.3 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RNA_pol_Rpc4 PF05132.14 GBG75218.1 - 0.12 12.8 3.1 0.2 12.1 3.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 PTPRCAP PF15713.5 GBG75218.1 - 0.14 12.4 24.7 0.24 11.7 24.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Na_trans_assoc PF06512.13 GBG75218.1 - 0.15 12.3 18.8 0.12 12.6 17.1 1.6 2 0 0 2 2 1 0 Sodium ion transport-associated Vfa1 PF08432.10 GBG75218.1 - 0.17 12.2 8.2 0.32 11.3 8.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.12 GBG75218.1 - 0.2 10.1 26.8 0.28 9.6 26.8 1.1 1 0 0 1 1 1 0 Mpp10 protein DARPP-32 PF05395.12 GBG75218.1 - 0.5 10.6 16.1 0.79 9.9 16.1 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Rrn6 PF10214.9 GBG75218.1 - 0.61 8.5 4.4 0.82 8.1 4.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 GBG75218.1 - 1.5 7.5 7.0 2.4 6.8 7.0 1.2 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 GBG75218.1 - 1.6 7.6 5.9 2.4 7.1 5.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 GBG75218.1 - 1.8 8.8 7.3 3.5 7.8 7.3 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SAPS PF04499.15 GBG75218.1 - 1.9 7.2 7.1 2.6 6.7 7.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 GBG75218.1 - 3 5.8 36.3 4.5 5.3 36.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi BAF1_ABF1 PF04684.13 GBG75218.1 - 3.5 6.6 13.3 4.9 6.1 13.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RR_TM4-6 PF06459.12 GBG75218.1 - 4.5 7.0 13.2 6.7 6.5 13.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 GBG75218.1 - 4.9 6.9 4.9 8.6 6.0 4.9 1.3 1 0 0 1 1 1 0 Connexin SpoIIIAH PF12685.7 GBG75218.1 - 6 6.6 13.5 9.2 6.0 13.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Hid1 PF12722.7 GBG75218.1 - 6.4 4.8 7.6 9.6 4.2 7.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.13 GBG75218.1 - 6.8 5.4 9.8 10 4.8 9.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MRNIP PF15749.5 GBG75218.1 - 6.9 7.4 10.3 14 6.5 10.3 1.4 1 0 0 1 1 1 0 MRN-interacting protein DUF4820 PF16091.5 GBG75218.1 - 9.6 5.5 10.8 14 4.9 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) BUD22 PF09073.10 GBG75218.1 - 9.7 5.4 28.3 14 4.9 28.3 1.1 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 GBG75218.1 - 9.9 6.1 16.1 18 5.2 16.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Myb_DNA-bind_4 PF13837.6 GBG75220.1 - 3.6e-10 40.1 1.0 1.8e-08 34.6 0.9 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG75220.1 - 0.0037 17.3 0.3 0.011 15.8 0.3 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Transcrip_act PF04949.13 GBG75220.1 - 0.03 14.2 0.3 0.065 13.1 0.1 1.5 2 0 0 2 2 2 0 Transcriptional activator MADF_DNA_bdg PF10545.9 GBG75220.1 - 0.12 12.7 0.3 0.39 11.1 0.3 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RmlD_sub_bind PF04321.17 GBG75221.1 - 0.15 11.1 0.2 0.27 10.3 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain rve PF00665.26 GBG75222.1 - 2.6e-10 40.5 0.0 7.5e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Jnk-SapK_ap_N PF09744.9 GBG75222.1 - 0.0023 18.2 3.2 0.0023 18.2 3.2 2.0 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 CCDC-167 PF15188.6 GBG75222.1 - 0.39 11.1 2.3 0.8 10.1 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TPR_MLP1_2 PF07926.12 GBG75222.1 - 0.98 9.5 11.4 0.14 12.2 6.5 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RT_RNaseH_2 PF17919.1 GBG75223.1 - 1.7e-25 88.9 0.0 2.8e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75223.1 - 1.7e-20 73.2 0.0 3.1e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75223.1 - 6.6e-10 38.9 0.1 1e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BAF1_ABF1 PF04684.13 GBG75224.1 - 0.026 13.6 3.4 0.03 13.4 3.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor YlbD_coat PF14071.6 GBG75224.1 - 0.091 13.0 1.6 0.14 12.4 1.6 1.4 1 0 0 1 1 1 0 Putative coat protein Secretin_N_2 PF07655.13 GBG75224.1 - 0.11 13.1 3.9 0.18 12.4 3.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DDE_Tnp_4 PF13359.6 GBG75225.1 - 4.8e-46 156.3 0.0 1.5e-26 92.9 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75225.1 - 5.9e-21 75.0 0.0 6.7e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG75225.1 - 1.4e-05 25.4 0.1 0.26 11.7 0.0 2.5 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG75225.1 - 4.6e-05 23.2 3.6 0.0091 15.7 0.0 3.9 4 0 0 4 4 4 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG75226.1 - 1.3e-08 35.1 1.7 2.1e-08 34.4 1.1 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG75226.1 - 0.0019 18.4 0.7 0.0036 17.5 0.7 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG75226.1 - 0.0031 17.6 0.5 0.006 16.6 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG75226.1 - 0.025 14.9 0.4 0.13 12.6 0.1 2.2 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG75226.1 - 0.049 13.8 0.7 0.11 12.7 0.7 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Enolase_C PF00113.22 GBG75227.1 - 7.2e-142 471.9 0.0 9.4e-142 471.5 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GBG75227.1 - 1.1e-58 197.0 0.1 2e-58 196.2 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GBG75227.1 - 1.6e-07 31.1 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GBG75227.1 - 0.00081 18.6 0.4 0.002 17.3 0.0 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus VSP PF03302.13 GBG75227.1 - 0.11 11.4 0.1 0.18 10.6 0.1 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein FKBP_C PF00254.28 GBG75229.1 - 2.4e-06 27.7 0.0 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyclin_N PF00134.23 GBG75230.1 - 2.4e-46 156.6 1.1 2.4e-46 156.6 1.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GBG75230.1 - 3.6e-37 127.1 0.2 7.8e-37 126.0 0.2 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain RRM_1 PF00076.22 GBG75232.1 - 8.8e-18 63.9 0.0 1.5e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 3HCDH_N PF02737.18 GBG75233.1 - 2e-56 190.7 0.2 2e-56 190.7 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 GBG75233.1 - 5.6e-45 153.6 0.0 1.5e-44 152.2 0.0 1.7 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 GBG75233.1 - 1.8e-27 95.8 0.1 1.3e-22 80.2 0.1 3.3 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 GBG75233.1 - 3.8e-23 82.5 0.0 1e-22 81.1 0.0 1.7 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UPF0203 PF05254.12 GBG75233.1 - 0.069 13.4 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) SNF2_N PF00176.23 GBG75235.1 - 4.7e-21 74.9 1.1 3.2e-09 36.0 0.0 3.1 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG75235.1 - 6.4e-12 45.8 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG75235.1 - 7.6e-07 29.3 8.7 0.00014 21.9 0.0 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit SDA1 PF05285.12 GBG75235.1 - 0.00027 20.5 35.0 0.00027 20.5 35.0 8.5 4 3 1 7 7 7 1 SDA1 AAA_19 PF13245.6 GBG75235.1 - 0.043 14.2 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain SBP_bac_6 PF13343.6 GBG75236.1 - 1.5e-25 90.1 0.0 2.1e-20 73.2 0.0 2.8 2 1 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 GBG75236.1 - 2.2e-13 50.7 0.0 4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF2052 PF09747.9 GBG75236.1 - 0.028 14.6 14.8 0.54 10.4 6.6 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DAG_kinase_N PF14513.6 GBG75236.1 - 0.45 10.7 4.4 2.4 8.4 0.8 2.5 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF4746 PF15928.5 GBG75236.1 - 1.1 8.7 14.9 3.5 7.0 6.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Eapp_C PF10238.9 GBG75236.1 - 2.2 8.4 8.5 7.8 6.6 2.2 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein Tim54 PF11711.8 GBG75236.1 - 2.8 6.7 12.4 3.6 6.3 0.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 GBG75236.1 - 4.2 6.8 10.6 15 5.0 0.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4471 PF14740.6 GBG75236.1 - 5.4 6.2 6.6 17 4.5 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) FAM176 PF14851.6 GBG75236.1 - 7.6 6.2 15.4 3.2 7.4 1.1 2.5 2 0 0 2 2 2 0 FAM176 family FmiP_Thoc5 PF09766.9 GBG75236.1 - 8 5.6 13.2 0.84 8.9 0.2 2.2 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 GATase_5 PF13507.6 GBG75237.1 - 1.2e-106 355.5 0.0 2e-106 354.8 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain mTERF PF02536.14 GBG75237.1 - 6e-63 212.6 5.0 5.6e-41 140.5 0.1 3.0 1 1 2 3 3 3 3 mTERF AIRS_C PF02769.22 GBG75237.1 - 5.6e-41 140.3 2.9 6.8e-22 78.3 0.9 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 GBG75237.1 - 8.5e-19 67.6 0.0 1.9e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 GBG75237.1 - 4e-11 43.3 0.0 1.2e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 GBG75237.1 - 0.0051 17.4 0.0 0.019 15.6 0.0 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PPDFL PF15060.6 GBG75238.1 - 0.068 13.7 0.2 0.2 12.2 0.1 1.9 1 1 0 1 1 1 0 Differentiation and proliferation regulator LMP PF04778.12 GBG75239.1 - 0.17 11.8 13.4 0.22 11.4 7.8 2.4 1 1 1 2 2 2 0 LMP repeated region Glyco_tran_WbsX PF14307.6 GBG75239.1 - 3.5 7.0 4.5 5.3 6.4 4.5 1.2 1 0 0 1 1 1 0 Glycosyltransferase WbsX Surp PF01805.20 GBG75240.1 - 7.6e-14 51.4 0.1 1.5e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Surp module G-patch PF01585.23 GBG75240.1 - 8e-14 51.3 3.6 1.8e-13 50.2 3.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GBG75240.1 - 0.00033 20.7 0.6 0.00033 20.7 0.6 2.0 2 0 0 2 2 2 1 G-patch domain DUF4322 PF14210.6 GBG75240.1 - 0.21 11.5 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4322) Rhomboid PF01694.22 GBG75241.1 - 1e-25 90.5 13.4 1e-25 90.5 13.4 1.8 2 0 0 2 2 2 1 Rhomboid family Peptidase_U4 PF03419.13 GBG75241.1 - 0.015 14.6 3.5 0.027 13.8 3.5 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF1751 PF08551.10 GBG75241.1 - 0.025 15.1 0.5 0.078 13.6 0.5 1.8 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 GBG75242.1 - 8.3e-26 90.8 13.4 8.3e-26 90.8 13.4 1.8 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 GBG75242.1 - 0.02 15.4 0.5 0.068 13.7 0.5 1.9 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Peptidase_U4 PF03419.13 GBG75242.1 - 0.28 10.4 8.0 0.018 14.3 3.2 1.5 2 0 0 2 2 2 0 Sporulation factor SpoIIGA RT_RNaseH PF17917.1 GBG75243.1 - 2.7e-20 72.6 0.0 7e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75243.1 - 8.6e-20 70.6 0.0 1.9e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75243.1 - 2.2e-17 62.9 1.3 5.1e-17 61.7 1.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75243.1 - 5.3e-17 62.1 0.0 1.2e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG75243.1 - 1e-06 29.2 0.1 2.2e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75243.1 - 5e-05 23.9 0.1 0.00011 22.7 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG75243.1 - 0.00075 19.3 0.1 0.0015 18.3 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG75243.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG75244.1 - 6.8e-22 77.7 0.0 1.4e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75244.1 - 1e-20 73.7 0.0 3.3e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Drf_GBD PF06371.13 GBG75244.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Rhomboid PF01694.22 GBG75245.1 - 2.5e-27 95.7 12.1 2.5e-27 95.7 12.1 1.8 2 0 0 2 2 2 1 Rhomboid family Peptidase_U4 PF03419.13 GBG75245.1 - 2.3 7.4 8.4 0.16 11.2 3.5 1.5 2 0 0 2 2 2 0 Sporulation factor SpoIIGA COQ9 PF08511.11 GBG75246.1 - 6.7e-14 51.4 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 COQ9 Caldesmon PF02029.15 GBG75247.1 - 1.2e-06 27.6 7.0 1.5e-06 27.3 7.0 1.1 1 0 0 1 1 1 1 Caldesmon DNA_pol_phi PF04931.13 GBG75247.1 - 0.00014 20.1 22.9 0.00023 19.5 22.9 1.3 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 GBG75247.1 - 0.00018 21.0 13.7 0.00028 20.4 13.7 1.3 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 GBG75247.1 - 0.012 14.1 19.6 0.018 13.5 19.6 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 GBG75247.1 - 0.026 13.5 1.2 0.055 12.4 1.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GBG75247.1 - 0.043 12.6 2.8 0.059 12.1 2.8 1.3 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GBG75247.1 - 0.072 12.4 20.2 0.11 11.9 20.2 1.2 1 0 0 1 1 1 0 BUD22 SpoIIP PF07454.11 GBG75247.1 - 0.21 11.0 8.6 0.35 10.3 8.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2151 PF10221.9 GBG75247.1 - 0.69 8.4 2.5 0.99 7.9 2.5 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator CPSF100_C PF13299.6 GBG75247.1 - 1.9 8.7 9.9 4.7 7.4 9.9 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 GBG75247.1 - 2.9 7.0 13.3 4.9 6.3 13.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 GBG75247.1 - 4.1 5.5 29.1 6.5 4.8 29.1 1.2 1 0 0 1 1 1 0 Nop14-like family Connexin PF00029.19 GBG75247.1 - 6.5 6.4 9.9 3.1 7.5 7.5 1.6 2 0 0 2 2 2 0 Connexin NPR3 PF03666.13 GBG75247.1 - 8.4 5.1 10.7 0.34 9.7 4.8 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 NAP PF00956.18 GBG75248.1 - 8.3e-68 228.5 5.7 2.8e-66 223.5 0.0 2.1 2 0 0 2 2 1 1 Nucleosome assembly protein (NAP) DUF2967 PF11179.8 GBG75248.1 - 0.00025 19.3 0.0 0.00038 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) RNA_pol_3_Rpc31 PF11705.8 GBG75248.1 - 0.00073 19.9 14.3 0.0013 19.0 14.3 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RNA_pol_Rpc4 PF05132.14 GBG75248.1 - 0.15 12.5 4.1 0.16 12.4 3.2 1.5 2 0 0 2 2 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 GBG75248.1 - 0.22 9.8 18.6 0.37 9.0 18.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 GBG75248.1 - 0.42 9.6 22.9 0.61 9.0 22.9 1.2 1 0 0 1 1 1 0 Paf1 TRM13 PF05206.14 GBG75248.1 - 0.42 10.1 2.9 0.67 9.4 2.9 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 NOA36 PF06524.12 GBG75248.1 - 0.55 9.5 18.8 0.84 8.9 18.8 1.2 1 0 0 1 1 1 0 NOA36 protein PTPRCAP PF15713.5 GBG75248.1 - 0.68 10.2 21.1 1.7 9.0 21.1 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RPA43_OB PF17875.1 GBG75248.1 - 0.78 10.4 10.4 1.8 9.2 10.4 1.6 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Prothymosin PF03247.14 GBG75248.1 - 0.98 9.9 39.2 2.1 8.8 39.2 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nop14 PF04147.12 GBG75248.1 - 1.2 7.3 25.2 2 6.6 25.2 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG75248.1 - 1.2 8.4 24.4 1.8 7.9 24.4 1.1 1 0 0 1 1 1 0 SDA1 TLP-20 PF06088.11 GBG75248.1 - 2 8.3 13.3 3.2 7.6 13.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Presenilin PF01080.17 GBG75248.1 - 2.1 7.0 5.5 2.8 6.6 5.5 1.2 1 0 0 1 1 1 0 Presenilin Nop53 PF07767.11 GBG75248.1 - 2.3 7.5 19.3 3.3 7.0 19.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CPSF100_C PF13299.6 GBG75248.1 - 2.3 8.4 10.1 3.9 7.6 10.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIF_alpha PF05793.12 GBG75248.1 - 3 6.3 24.2 3.7 6.0 24.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.12 GBG75248.1 - 3.1 7.5 12.9 4.9 6.9 12.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GEN1_C PF18380.1 GBG75248.1 - 4.8 8.1 13.3 11 7.0 13.3 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain BUD22 PF09073.10 GBG75248.1 - 4.9 6.4 18.5 6.5 6.0 18.5 1.2 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 GBG75248.1 - 7.9 6.3 22.4 7.8 6.3 20.2 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region FRQ PF09421.10 GBG75248.1 - 8.1 4.3 11.1 12 3.8 11.1 1.1 1 0 0 1 1 1 0 Frequency clock protein DUF2457 PF10446.9 GBG75248.1 - 9.2 5.3 30.4 13 4.8 30.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Connexin PF00029.19 GBG75248.1 - 9.7 5.9 8.5 17 5.1 8.5 1.4 1 0 0 1 1 1 0 Connexin Tim17 PF02466.19 GBG75249.1 - 1.1e-18 67.6 8.5 1.1e-18 67.6 8.5 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RT_RNaseH PF17917.1 GBG75250.1 - 7e-19 68.1 0.2 1.6e-18 66.9 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TP6A_N PF04406.14 GBG75250.1 - 2.5e-16 59.4 0.3 7e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase RT_RNaseH_2 PF17919.1 GBG75250.1 - 1.9e-10 40.6 0.0 4.9e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TP6A_N PF04406.14 GBG75251.1 - 2.1e-16 59.6 0.3 6.3e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase VASP_tetra PF08776.11 GBG75251.1 - 0.68 9.6 9.9 2.6 7.7 1.1 3.9 4 0 0 4 4 4 0 VASP tetramerisation domain MIP PF00230.20 GBG75252.1 - 3.7e-59 200.2 11.6 5.8e-59 199.6 11.6 1.3 1 0 0 1 1 1 1 Major intrinsic protein Myb_DNA-bind_4 PF13837.6 GBG75252.1 - 0.05 14.0 0.2 0.18 12.2 0.2 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain SPX PF03105.19 GBG75252.1 - 7.5 6.4 6.1 2.3 8.1 2.9 1.7 2 0 0 2 2 2 0 SPX domain DDE_Tnp_4 PF13359.6 GBG75254.1 - 1.9e-21 76.4 0.1 2.2e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75254.1 - 1.6e-11 44.2 0.0 7.3e-08 32.3 0.0 2.2 1 1 1 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG75254.1 - 0.08 12.6 0.3 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG75255.1 - 1.5e-30 105.2 0.0 2.5e-16 59.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75255.1 - 3.4e-29 101.2 0.0 6.7e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75255.1 - 9.7e-16 57.6 0.0 2.1e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75255.1 - 3.3e-11 43.4 0.0 1.3e-10 41.5 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG75255.1 - 0.00044 20.4 0.0 0.00095 19.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger WD40 PF00400.32 GBG75256.1 - 0.14 13.1 1.8 0.33 11.9 0.7 2.1 2 1 1 3 3 3 0 WD domain, G-beta repeat WD40 PF00400.32 GBG75258.1 - 2.7e-11 43.8 5.5 2.1e-05 25.2 0.2 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat eIF2A PF08662.11 GBG75258.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A CAF1C_H4-bd PF12265.8 GBG75259.1 - 3.7e-17 62.3 0.2 1.5e-16 60.4 0.2 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GBG75259.1 - 0.12 13.3 0.0 4.2 8.4 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat MtN3_slv PF03083.16 GBG75260.1 - 5e-21 74.5 5.3 8.1e-21 73.9 5.3 1.2 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange rve PF00665.26 GBG75260.1 - 9.9e-08 32.2 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG75260.1 - 0.0015 18.6 0.5 0.0024 18.0 0.5 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG75261.1 - 1.7e-17 63.3 0.0 3.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75261.1 - 1.1e-07 32.1 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Cwf_Cwc_15 PF04889.12 GBG75261.1 - 0.18 11.5 25.7 0.28 10.9 25.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG75261.1 - 1.2 8.5 31.0 1.7 8.0 31.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG75261.1 - 1.7 6.8 31.4 2.5 6.2 31.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG75261.1 - 2 6.6 23.2 2.7 6.2 23.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG75261.1 - 4.6 6.7 17.9 6.8 6.1 17.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 GBG75261.1 - 8.2 5.6 30.8 12 5.1 30.8 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GBG75261.1 - 9.1 4.9 10.1 13 4.4 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Integrase_H2C2 PF17921.1 GBG75262.1 - 4.5e-18 65.1 0.3 7.7e-18 64.4 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG75262.1 - 0.021 15.0 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger FtsK_4TM PF13491.6 GBG75262.1 - 0.05 13.3 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE Rrn6 PF10214.9 GBG75262.1 - 2.4 6.5 6.4 3.2 6.1 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF659 PF04937.15 GBG75263.1 - 2e-31 108.9 0.1 5.3e-31 107.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG75263.1 - 3.6e-05 23.5 0.0 7.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCHC_6 PF15288.6 GBG75264.1 - 0.0027 17.5 2.9 0.0077 16.0 2.9 1.9 1 0 0 1 1 1 1 Zinc knuckle GDP_Man_Dehyd PF16363.5 GBG75265.1 - 2.6e-10 40.2 0.0 3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG75265.1 - 0.0016 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RVT_1 PF00078.27 GBG75266.1 - 6.5e-36 123.9 0.0 1.1e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75266.1 - 5e-31 106.7 0.0 1.7e-30 105.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75266.1 - 3.1e-29 101.3 0.0 1e-28 99.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-C3HC4_3 PF13920.6 GBG75267.1 - 3.2e-12 46.1 12.1 5.1e-12 45.5 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG75267.1 - 0.019 14.8 12.3 0.037 13.9 12.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GBG75267.1 - 0.14 12.5 13.9 0.24 11.8 13.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 GBG75267.1 - 0.46 10.5 13.1 0.87 9.6 13.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_p24 PF05073.12 GBG75267.1 - 6.7 6.4 6.5 44 3.8 6.5 2.4 1 1 0 1 1 1 0 Baculovirus P24 capsid protein zf-P11 PF03854.14 GBG75267.1 - 9.9 5.9 10.3 17 5.1 10.3 1.3 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_3 PF13920.6 GBG75268.1 - 3.2e-12 46.1 12.1 5.1e-12 45.5 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG75268.1 - 0.019 14.8 12.3 0.037 13.9 12.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GBG75268.1 - 0.14 12.5 13.9 0.24 11.8 13.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 GBG75268.1 - 0.46 10.5 13.1 0.87 9.6 13.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_p24 PF05073.12 GBG75268.1 - 6.7 6.4 6.5 44 3.8 6.5 2.4 1 1 0 1 1 1 0 Baculovirus P24 capsid protein zf-P11 PF03854.14 GBG75268.1 - 9.9 5.9 10.3 17 5.1 10.3 1.3 1 0 0 1 1 1 0 P-11 zinc finger GTP_EFTU PF00009.27 GBG75270.1 - 1.3e-53 181.5 0.0 2e-53 180.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GBG75270.1 - 4.7e-39 133.2 0.1 1.1e-38 132.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GBG75270.1 - 8.8e-14 51.7 0.2 8.8e-14 51.7 0.2 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG75270.1 - 0.00017 21.6 0.3 0.00078 19.5 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GBG75270.1 - 0.00022 20.7 0.1 0.0044 16.5 0.0 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 GBG75270.1 - 0.029 14.3 2.7 0.043 13.7 0.2 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 GBG75270.1 - 0.12 12.4 0.3 17 5.4 0.2 2.4 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 GBG75270.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU_D3 PF03143.17 GBG75271.1 - 3.4e-39 133.6 0.1 5e-39 133.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.27 GBG75271.1 - 9.1e-11 41.6 0.6 2.1e-10 40.5 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 GBG75271.1 - 0.015 14.5 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit GTP_EFTU PF00009.27 GBG75272.1 - 1.3e-53 181.5 0.0 2e-53 180.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GBG75272.1 - 4.7e-39 133.2 0.1 1.1e-38 132.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GBG75272.1 - 8.8e-14 51.7 0.2 8.8e-14 51.7 0.2 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG75272.1 - 0.00017 21.6 0.3 0.00078 19.5 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GBG75272.1 - 0.00022 20.7 0.1 0.0044 16.5 0.0 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 GBG75272.1 - 0.029 14.3 2.7 0.043 13.7 0.2 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 GBG75272.1 - 0.12 12.4 0.3 17 5.4 0.2 2.4 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 GBG75272.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 GBG75273.1 - 0.11 12.6 1.2 0.22 11.6 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4309 PF14172.6 GBG75273.1 - 0.13 12.3 0.0 29 4.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4309) GTP_EFTU PF00009.27 GBG75274.1 - 1.3e-53 181.5 0.0 2e-53 180.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GBG75274.1 - 4.7e-39 133.2 0.1 1.1e-38 132.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GBG75274.1 - 8.8e-14 51.7 0.2 8.8e-14 51.7 0.2 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG75274.1 - 0.00017 21.6 0.3 0.00078 19.5 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GBG75274.1 - 0.00022 20.7 0.1 0.0044 16.5 0.0 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 GBG75274.1 - 0.029 14.3 2.7 0.043 13.7 0.2 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 GBG75274.1 - 0.12 12.4 0.3 17 5.4 0.2 2.4 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 GBG75274.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mpp10 PF04006.12 GBG75275.1 - 0.12 10.8 24.2 0.11 10.9 24.2 1.1 1 0 0 1 1 1 0 Mpp10 protein SpoIIP PF07454.11 GBG75275.1 - 0.3 10.5 10.1 0.28 10.6 10.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 GBG75275.1 - 0.32 11.1 0.9 0.27 11.4 0.9 1.1 1 0 0 1 1 1 0 DDHD domain NPR3 PF03666.13 GBG75275.1 - 0.34 9.7 7.1 0.31 9.8 7.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GBG75275.1 - 0.6 8.8 7.8 0.54 9.0 7.8 1.0 1 0 0 1 1 1 0 Presenilin DUF4471 PF14740.6 GBG75275.1 - 0.7 9.1 4.7 0.63 9.2 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Zip PF02535.22 GBG75275.1 - 0.8 8.9 7.2 0.73 9.0 7.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3c_N PF05470.12 GBG75275.1 - 0.85 7.9 7.9 0.77 8.0 7.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.10 GBG75275.1 - 1.4 8.2 29.3 1.6 8.0 29.3 1.1 1 0 0 1 1 1 0 BUD22 Eapp_C PF10238.9 GBG75275.1 - 1.4 9.0 6.4 1.6 8.8 6.4 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein FYDLN_acid PF09538.10 GBG75275.1 - 6.7 7.4 19.7 2.4 8.9 17.5 1.5 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) CTU2 PF10288.9 GBG75275.1 - 7.2 6.9 7.4 9 6.6 7.4 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Plasmodium_Vir PF05795.11 GBG75275.1 - 7.3 5.9 11.2 7 6.0 11.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RVT_1 PF00078.27 GBG75276.1 - 1.9e-21 76.6 0.2 3.1e-11 43.2 0.0 3.8 3 1 1 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75276.1 - 1.9e-17 63.1 2.4 2.1e-17 62.9 0.2 2.3 2 0 0 2 2 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG75276.1 - 2.6e-10 40.5 0.1 8.1e-10 38.9 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG75276.1 - 1e-06 29.3 0.0 3.1e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75276.1 - 1.3e-06 28.9 0.0 3.5e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG75276.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG75276.1 - 0.00019 21.2 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG75276.1 - 0.01 15.8 0.0 0.046 13.8 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Nif11 PF07862.11 GBG75276.1 - 0.029 14.7 3.8 0.16 12.3 3.8 2.4 1 0 0 1 1 1 0 Nif11 domain Cnl2_NKP2 PF09447.10 GBG75276.1 - 0.49 10.6 6.0 6 7.1 2.5 3.5 3 0 0 3 3 3 0 Cnl2/NKP2 family protein BLOC1_2 PF10046.9 GBG75276.1 - 1.6 9.1 9.4 1.6 9.1 4.4 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GBG75276.1 - 6.3 7.3 7.6 23 5.5 1.2 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.24 GBG75276.1 - 7.4 6.5 8.3 52 3.7 3.6 3.1 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD GTP_EFTU_D3 PF03143.17 GBG75277.1 - 7.5e-39 132.5 0.1 1.2e-38 131.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.27 GBG75277.1 - 7.4e-35 120.3 0.6 1.4e-34 119.4 0.3 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GBG75277.1 - 0.0022 18.0 0.2 0.0095 16.0 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GBG75277.1 - 0.024 14.7 0.2 8.4 6.4 0.2 2.3 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 GBG75277.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 GBG75277.1 - 0.13 11.4 0.2 0.24 10.5 0.1 1.5 1 1 1 2 2 2 0 G-protein alpha subunit zf-CCHC PF00098.23 GBG75278.1 - 1.6e-05 24.7 3.4 1.6e-05 24.7 3.4 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG75278.1 - 0.009 16.0 1.5 0.009 16.0 1.5 2.4 2 0 0 2 2 2 1 Zinc knuckle DUF2058 PF09831.9 GBG75278.1 - 0.13 12.4 11.3 0.31 11.2 11.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) EMC3_TMCO1 PF01956.16 GBG75278.1 - 6.6 6.4 5.9 12 5.6 5.9 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like bZIP_2 PF07716.15 GBG75279.1 - 2.6e-07 30.6 9.9 2.6e-07 30.6 9.9 3.4 3 1 1 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.21 GBG75279.1 - 0.00046 20.2 10.4 0.0039 17.3 9.5 2.5 1 1 1 2 2 2 1 bZIP transcription factor NYD-SP28_assoc PF14775.6 GBG75279.1 - 7.6 6.7 6.3 5.7 7.1 0.7 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain Goodbye PF17109.5 GBG75281.1 - 0.054 14.0 0.0 0.066 13.7 0.0 1.2 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain FERM_f0 PF16511.5 GBG75281.1 - 6.2 7.2 9.9 2e+02 2.3 0.1 3.6 1 1 1 2 2 2 0 N-terminal or F0 domain of Talin-head FERM WD40 PF00400.32 GBG75282.1 - 7.2e-23 80.4 8.2 1.7e-06 28.6 0.1 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG75282.1 - 8.7e-06 25.9 0.0 0.13 12.5 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG75282.1 - 0.38 9.7 1.5 4.6 6.1 0.2 2.5 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LIM PF00412.22 GBG75283.1 - 6.4e-21 74.3 20.0 1.7e-10 41.0 6.4 2.4 2 0 0 2 2 2 2 LIM domain RecQ_Zn_bind PF16124.5 GBG75283.1 - 0.015 16.0 3.6 0.015 16.0 3.6 2.1 2 0 0 2 2 2 0 RecQ zinc-binding C1_1 PF00130.22 GBG75283.1 - 1.2 9.1 18.1 2 8.4 3.9 3.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LCCL PF03815.19 GBG75284.1 - 6.1 7.0 14.7 18 5.5 0.2 4.7 1 1 3 4 4 4 0 LCCL domain Rcd1 PF04078.13 GBG75285.1 - 2.8e-128 426.7 0.1 3.2e-128 426.5 0.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SchA_CurD PF04486.12 GBG75285.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 SchA/CurD like domain Glycos_transf_2 PF00535.26 GBG75287.1 - 7e-31 107.3 0.0 8.4e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG75287.1 - 9.8e-13 48.5 0.0 1.1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GBG75287.1 - 0.00081 18.9 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GBG75287.1 - 0.0094 15.4 0.0 0.021 14.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF4471 PF14740.6 GBG75287.1 - 0.065 12.5 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) PurL_C PF16904.5 GBG75287.1 - 0.076 13.3 0.0 30 5.0 0.1 2.8 1 1 2 3 3 3 0 Phosphoribosylformylglycinamidine synthase II C-terminus ArsA_ATPase PF02374.15 GBG75288.1 - 1.2e-73 248.0 0.0 1.7e-73 247.5 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 GBG75288.1 - 1.4e-09 38.0 0.0 2.8e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 GBG75288.1 - 1.1e-07 31.6 2.8 0.00022 20.8 0.2 2.9 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 GBG75288.1 - 5.4e-06 26.4 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 GBG75288.1 - 0.00018 21.1 0.0 0.00057 19.4 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 GBG75288.1 - 0.00026 20.6 0.1 0.0076 15.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 GBG75288.1 - 0.0014 18.3 0.3 0.013 15.2 0.1 2.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 GBG75288.1 - 0.0082 16.1 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase ATPase PF06745.13 GBG75288.1 - 0.0096 15.3 0.4 0.025 13.9 0.0 1.8 2 0 0 2 2 2 1 KaiC NACHT PF05729.12 GBG75288.1 - 0.027 14.4 0.3 0.087 12.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 GBG75288.1 - 0.032 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 GBG75288.1 - 0.036 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.15 GBG75288.1 - 0.064 13.3 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 GBG75288.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 GBG75288.1 - 0.075 12.7 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 GBG75288.1 - 0.087 12.3 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DnaB_C PF03796.15 GBG75288.1 - 0.099 12.0 0.2 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Med9 PF07544.13 GBG75288.1 - 0.1 12.7 0.2 0.27 11.3 0.2 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 tRNA_Me_trans PF03054.16 GBG75289.1 - 3.9e-113 377.8 0.0 3.4e-104 348.5 0.0 2.3 2 0 0 2 2 2 2 tRNA methyl transferase MeaB PF03308.16 GBG75289.1 - 1e-45 155.8 0.0 4.7e-38 130.7 0.0 2.3 1 1 1 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ThiI PF02568.14 GBG75289.1 - 2.8e-05 23.8 0.0 5.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) cobW PF02492.19 GBG75289.1 - 7.3e-05 22.4 0.7 0.024 14.2 0.0 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NAD_synthase PF02540.17 GBG75289.1 - 0.014 14.6 0.0 0.036 13.2 0.0 1.7 1 0 0 1 1 1 0 NAD synthase AAA_18 PF13238.6 GBG75289.1 - 0.019 15.5 0.1 0.061 13.9 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG75289.1 - 0.024 14.4 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 GBG75289.1 - 0.078 12.4 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 GBG75289.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Asn_synthase PF00733.21 GBG75289.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase ABC_tran PF00005.27 GBG75289.1 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 GBG75289.1 - 0.17 11.9 0.1 0.37 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 GBG75289.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 GBG75289.1 - 0.22 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 GBG75290.1 - 4.9e-89 297.9 0.1 7.6e-89 297.2 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 GBG75290.1 - 5.1e-08 32.7 0.2 1.6e-06 27.8 0.2 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 GBG75290.1 - 0.0071 16.2 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 GBG75290.1 - 0.0073 16.0 0.0 0.029 14.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GBG75290.1 - 0.008 15.9 0.2 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 GBG75290.1 - 0.014 15.9 1.6 0.045 14.3 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GBG75290.1 - 0.052 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GBG75290.1 - 0.059 13.7 0.1 0.25 11.7 0.1 2.1 1 0 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 GBG75290.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.15 GBG75290.1 - 0.093 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 NTPase SRP54 PF00448.22 GBG75290.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 GBG75290.1 - 0.13 12.5 0.1 0.75 10.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain C2 PF00168.30 GBG75291.1 - 3.2e-12 46.6 0.0 6.9e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain DnaJ PF00226.31 GBG75292.1 - 2.6e-18 65.9 0.8 4.1e-18 65.2 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain Chorion_2 PF03964.15 GBG75292.1 - 0.00092 20.0 8.4 0.00092 20.0 8.4 4.3 3 2 1 4 4 4 1 Chorion family 2 Peptidase_M3_N PF08439.10 GBG75294.1 - 0.044 14.1 0.2 0.12 12.7 0.2 1.7 1 0 0 1 1 1 0 Oligopeptidase F MADF_DNA_bdg PF10545.9 GBG75294.1 - 0.045 14.1 0.9 2.8 8.3 0.2 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like BolA PF01722.18 GBG75295.1 - 1.1e-18 67.2 0.0 3.2e-18 65.8 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein RVT_1 PF00078.27 GBG75296.1 - 1.7e-17 63.7 0.1 9e-12 45.0 0.0 2.8 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG75296.1 - 1.8e-06 28.1 0.6 6.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG75296.1 - 1.2e-05 25.9 0.0 2.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75296.1 - 2.7e-05 24.7 0.0 7.5e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG75296.1 - 3.1e-05 23.8 0.0 6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75296.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF2497 PF10691.9 GBG75296.1 - 0.12 12.8 0.2 0.77 10.2 0.2 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) CLZ PF16526.5 GBG75296.1 - 8.4 6.8 7.9 19 5.7 2.7 3.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels dCMP_cyt_deam_1 PF00383.23 GBG75297.1 - 1.3e-23 82.8 0.9 2.1e-23 82.1 0.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GBG75297.1 - 8.9e-22 77.3 1.0 2.3e-21 76.0 1.0 1.6 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GBG75297.1 - 5.1e-06 26.6 1.2 9.8e-06 25.7 1.2 1.5 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 GBG75297.1 - 0.053 13.6 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 GBG75297.1 - 0.15 12.1 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 APOBEC2 zf-CCHC PF00098.23 GBG75298.1 - 1.1e-07 31.6 1.9 1.8e-07 30.9 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG75298.1 - 0.053 13.3 0.5 0.11 12.3 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG75298.1 - 0.41 10.5 1.7 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle CAF-1_p150 PF11600.8 GBG75298.1 - 7.4 6.2 33.7 1.3 8.7 24.1 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Beta_helix PF13229.6 GBG75299.1 - 1.5e-12 47.6 41.6 0.01 15.7 2.0 6.6 2 2 3 5 5 5 5 Right handed beta helix region TRP PF06011.12 GBG75299.1 - 1.5e-06 27.2 14.3 7.7e-06 24.9 14.3 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TFIIA PF03153.13 GBG75299.1 - 0.25 11.3 11.3 0.41 10.6 11.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 GBG75299.1 - 0.27 10.0 0.1 0.39 9.4 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ephrin_rec_like PF07699.13 GBG75299.1 - 0.32 10.8 15.6 0.11 12.3 3.0 3.1 3 0 0 3 3 3 0 Putative ephrin-receptor like MDM10 PF12519.8 GBG75300.1 - 0.57 9.0 7.6 0.57 9.0 7.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Cellulose_synt PF03552.14 GBG75300.1 - 0.63 8.5 6.0 0.72 8.3 6.0 1.0 1 0 0 1 1 1 0 Cellulose synthase SOBP PF15279.6 GBG75300.1 - 0.66 10.5 7.3 0.75 10.3 7.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Endostatin PF06482.11 GBG75300.1 - 0.95 8.9 9.2 1.3 8.5 9.2 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin TFIIA PF03153.13 GBG75300.1 - 1 9.3 14.0 1.3 9.0 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 GBG75300.1 - 1.1 9.4 5.6 1.3 9.2 5.6 1.3 1 0 0 1 1 1 0 DDHD domain EOS1 PF12326.8 GBG75300.1 - 2.4 8.1 6.7 4 7.3 6.7 1.5 1 0 0 1 1 1 0 N-glycosylation protein SLC12 PF03522.15 GBG75300.1 - 2.4 7.1 11.4 2.5 7.0 11.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CLN3 PF02487.17 GBG75300.1 - 2.5 7.1 3.9 2.8 6.9 3.9 1.2 1 0 0 1 1 1 0 CLN3 protein NARP1 PF12569.8 GBG75300.1 - 3.2 6.5 19.3 4.5 6.1 19.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 GBG75300.1 - 3.9 6.6 7.0 4.1 6.5 7.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_11 PF13086.6 GBG75300.1 - 3.9 7.2 15.5 5.6 6.7 15.5 1.3 1 0 0 1 1 1 0 AAA domain MCM_bind PF09739.9 GBG75300.1 - 8.4 4.7 15.2 11 4.3 15.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Histone_H2A_C PF16211.5 GBG75301.1 - 1.9e-19 69.1 1.1 3.1e-19 68.4 1.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GBG75301.1 - 7.1e-15 55.5 0.0 9.5e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG75301.1 - 3.2e-07 30.5 0.0 4.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DDE_Tnp_4 PF13359.6 GBG75302.1 - 8.1e-29 100.3 0.0 2.6e-28 98.7 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75302.1 - 5.7e-15 55.5 0.0 8.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG75302.1 - 0.0021 17.7 1.3 1.4 8.5 0.8 2.5 2 0 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG75303.1 - 2.6e-06 27.7 2.0 2.6e-06 27.7 2.0 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG75303.1 - 0.00093 19.4 0.4 0.0023 18.2 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG75303.1 - 0.0022 18.3 0.6 0.0022 18.3 0.6 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG75303.1 - 0.0047 17.0 1.9 0.012 15.6 0.4 2.4 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain NAM-associated PF14303.6 GBG75303.1 - 2.4 8.8 6.8 0.79 10.4 0.2 2.3 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain Nop53 PF07767.11 GBG75303.1 - 3 7.1 8.3 0.28 10.5 3.7 1.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Collagen PF01391.18 GBG75304.1 - 1.2 9.0 26.3 7.5 6.4 0.0 5.3 3 2 0 3 3 3 0 Collagen triple helix repeat (20 copies) RVT_1 PF00078.27 GBG75305.1 - 1.6e-26 93.2 0.1 2.9e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG75305.1 - 0.0012 18.7 0.0 0.0032 17.2 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG75305.1 - 0.0051 17.3 0.0 0.03 14.9 0.0 2.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75305.1 - 0.0069 17.0 0.0 0.086 13.5 0.0 2.7 2 1 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG75305.1 - 0.0071 16.6 0.3 0.25 11.7 0.0 3.4 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG75305.1 - 1.1 8.6 7.1 3.1 7.1 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CLZ PF16526.5 GBG75305.1 - 4.3 7.8 7.2 0.5 10.7 0.3 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_TATA_bd PF12325.8 GBG75305.1 - 9.5 6.5 9.0 3.2 8.0 0.1 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding eIF3_subunit PF08597.10 GBG75306.1 - 4.3 7.2 13.4 6.5 6.6 13.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RT_RNaseH_2 PF17919.1 GBG75307.1 - 1.3e-90 297.9 0.0 5.4e-32 109.8 0.0 3.9 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75307.1 - 8.2e-87 286.4 3.7 1.2e-28 99.5 0.1 5.0 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75307.1 - 4.4e-73 245.5 1.5 1.9e-26 92.9 0.1 4.8 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75307.1 - 1e-15 57.6 1.1 3.1e-15 56.0 1.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75307.1 - 5.2e-08 33.1 0.1 6.9e-05 23.0 0.1 3.8 3 0 0 3 3 3 1 Integrase core domain Retrotrans_gag PF03732.17 GBG75307.1 - 5.5e-07 29.8 7.8 0.83 10.0 0.1 7.4 6 0 0 6 6 6 2 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG75307.1 - 1.3e-06 28.9 0.1 5.3e-06 26.9 0.0 2.2 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75307.1 - 1.3e-06 28.9 0.0 3.4e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG75307.1 - 6.9e-05 22.6 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Clathrin PF00637.20 GBG75307.1 - 8.7e-05 22.4 11.4 0.0066 16.3 0.2 4.9 4 1 1 5 5 5 2 Region in Clathrin and VPS Asp_protease PF09668.10 GBG75307.1 - 0.00015 21.5 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease TPR_1 PF00515.28 GBG75307.1 - 0.17 11.8 8.3 22 5.1 0.4 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 GBG75308.1 - 2e-19 69.5 0.0 4.8e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75308.1 - 8.5e-16 58.1 0.0 8.2e-15 55.0 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75308.1 - 1.1e-13 51.1 0.0 2.7e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG75308.1 - 0.00047 19.7 0.0 0.0013 18.2 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG75308.1 - 0.00049 20.6 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG75308.1 - 0.00069 19.9 0.0 0.0021 18.3 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75308.1 - 0.0082 16.8 0.0 0.021 15.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG75310.1 - 3.1e-33 113.8 0.1 7.3e-33 112.6 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75310.1 - 2.2e-29 101.8 0.0 4.1e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TPR_2 PF07719.17 GBG75311.1 - 0.051 13.7 2.9 5.8 7.3 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG75311.1 - 0.27 12.1 1.7 11 7.1 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG75311.1 - 0.39 11.0 2.0 3.3 8.2 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG75312.1 - 1.7e-26 93.1 0.1 3e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75312.1 - 5.2e-17 61.7 0.1 3.8e-16 58.9 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75312.1 - 4.2e-09 36.6 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG75312.1 - 1.1e-06 28.4 0.0 3.1e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75312.1 - 1.3e-06 29.0 0.0 3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75312.1 - 0.00043 20.8 0.0 0.0016 18.9 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG75312.1 - 0.0029 17.8 1.4 0.17 12.2 0.0 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein K1377 PF15352.6 GBG75312.1 - 5.5 5.1 8.0 5.8 5.0 3.3 2.0 2 0 0 2 2 2 0 Susceptibility to monomelic amyotrophy RT_RNaseH_2 PF17919.1 GBG75313.1 - 1.1e-34 118.4 0.1 5.6e-34 116.2 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75313.1 - 2.3e-31 109.0 0.1 4.7e-31 108.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75313.1 - 1.5e-29 102.4 0.1 5.8e-29 100.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75313.1 - 5.7e-15 55.6 0.0 1.6e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain TPR_14 PF13428.6 GBG75313.1 - 0.12 13.3 0.1 28 5.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RT_RNaseH PF17917.1 GBG75315.1 - 2.9e-25 88.6 0.0 6e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75315.1 - 3.5e-22 78.3 0.0 7.2e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75315.1 - 8.7e-10 38.8 0.0 2.8e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG75315.1 - 5e-05 23.3 0.1 0.00015 21.8 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain STI1 PF17830.1 GBG75315.1 - 0.042 13.8 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 STI1 domain tRNA_lig_CPD PF08302.11 GBG75315.1 - 0.048 13.1 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain rve_3 PF13683.6 GBG75315.1 - 0.13 12.1 0.0 0.69 9.7 0.0 2.4 1 0 0 1 1 1 0 Integrase core domain YabA PF06156.13 GBG75315.1 - 0.14 12.8 0.5 0.6 10.8 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Phage_GPO PF05929.11 GBG75315.1 - 0.15 11.7 5.4 2.3 7.8 0.0 2.5 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase GCN5L1 PF06320.13 GBG75315.1 - 0.67 10.1 3.6 1.9 8.6 3.6 1.8 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) RT_RNaseH_2 PF17919.1 GBG75316.1 - 2.1e-30 104.7 0.0 4.7e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75316.1 - 2.1e-29 102.6 0.1 4e-29 101.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75316.1 - 3.4e-27 94.8 0.1 6.9e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75316.1 - 3.3e-15 56.3 0.0 8e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG75316.1 - 1.3e-14 54.0 0.0 3.2e-13 49.6 0.0 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG75316.1 - 0.0021 18.2 0.0 0.006 16.8 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger eIF-1a PF01176.19 GBG75316.1 - 0.0096 15.7 0.1 0.023 14.5 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Rhamno_transf PF11316.8 GBG75316.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase HALZ PF02183.18 GBG75316.1 - 0.048 13.9 1.3 0.17 12.2 1.3 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 GBG75316.1 - 0.21 11.4 2.1 0.6 9.9 2.1 1.7 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 GBG75316.1 - 1 9.5 7.5 0.31 11.2 2.9 2.5 2 0 0 2 2 2 0 Basic region leucine zipper GvpL_GvpF PF06386.11 GBG75316.1 - 3 7.7 6.0 5.6 6.8 6.0 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ORC_WH_C PF18137.1 GBG75317.1 - 1.7 8.7 6.6 0.32 11.1 0.9 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal SAS4 PF15460.6 GBG75317.1 - 3.2 7.9 7.4 12 6.0 4.2 2.7 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 RT_RNaseH_2 PF17919.1 GBG75318.1 - 1e-33 115.3 0.0 2.3e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75318.1 - 2.7e-28 98.3 0.0 6.2e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75318.1 - 2.8e-26 92.4 0.0 4.6e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75318.1 - 3.2e-17 62.4 0.8 7e-17 61.3 0.8 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG75318.1 - 1.4e-07 31.4 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75318.1 - 0.0013 19.3 0.0 0.0027 18.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75318.1 - 0.0039 17.7 0.0 0.008 16.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG75318.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF2201_N PF13203.6 GBG75319.1 - 0.037 13.6 1.0 0.05 13.2 1.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.14 GBG75319.1 - 0.082 11.2 9.4 0.11 10.8 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Imm5 PF14423.6 GBG75319.1 - 0.17 12.1 1.1 0.4 10.9 0.2 2.1 2 0 0 2 2 2 0 Immunity protein Imm5 SDA1 PF05285.12 GBG75319.1 - 1.1 8.6 14.9 1.5 8.1 14.9 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG75319.1 - 3.4 7.1 7.2 4.6 6.7 7.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.12 GBG75319.1 - 3.5 7.4 8.2 5.1 6.8 8.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 GBG75319.1 - 4.7 5.3 14.1 5.8 5.0 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG75319.1 - 7.7 5.2 8.0 12 4.5 8.0 1.3 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 GBG75319.1 - 7.7 4.9 5.3 11 4.4 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CCDC106 PF15794.5 GBG75319.1 - 9.8 5.8 10.1 17 5.1 10.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RVT_1 PF00078.27 GBG75321.1 - 1e-27 97.1 0.0 1.7e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75321.1 - 8.3e-18 64.6 0.3 8.3e-18 64.6 0.3 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75321.1 - 4.4e-15 55.5 0.1 9.1e-15 54.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75321.1 - 1.5e-12 47.7 0.0 4.1e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG75321.1 - 3e-10 40.0 2.4 1.4e-09 37.9 0.1 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG75321.1 - 0.016 15.4 0.1 0.07 13.4 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger Apc13p PF05839.11 GBG75321.1 - 0.2 11.9 0.9 0.56 10.4 0.9 1.7 1 0 0 1 1 1 0 Apc13p protein RT_RNaseH_2 PF17919.1 GBG75322.1 - 1.2e-29 102.3 0.0 3.2e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75322.1 - 3.9e-28 97.8 0.5 9.5e-28 96.6 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75322.1 - 6.9e-13 48.5 0.1 2.3e-12 46.8 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Ssu72 PF04722.13 GBG75322.1 - 0.073 12.6 0.3 0.4 10.2 0.2 2.0 1 1 0 1 1 1 0 Ssu72-like protein Phage_GPO PF05929.11 GBG75322.1 - 0.3 10.7 0.1 0.3 10.7 0.1 3.3 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG75323.1 - 2.1e-31 109.2 0.1 3.7e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75323.1 - 2.2e-29 101.8 0.0 6e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75323.1 - 3.1e-28 97.8 0.0 8.2e-28 96.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75323.1 - 1e-18 67.2 2.1 1.2e-18 67.0 0.5 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG75323.1 - 1.6e-15 57.3 0.0 5.9e-15 55.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG75323.1 - 0.002 18.3 0.0 0.0062 16.7 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Pentapeptide_4 PF13599.6 GBG75326.1 - 1.1e-07 32.0 0.0 9.7 6.4 0.0 7.6 4 3 2 6 6 6 3 Pentapeptide repeats (9 copies) DUF1118 PF06549.12 GBG75326.1 - 0.33 11.3 4.2 30 4.9 0.1 4.9 5 1 0 5 5 5 0 Protein of unknown function (DUF1118) RVT_1 PF00078.27 GBG75327.1 - 5.7e-32 111.0 0.1 1.1e-31 110.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75327.1 - 5.3e-31 107.0 0.0 1.4e-30 105.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75327.1 - 4e-30 103.8 0.0 1.3e-29 102.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75327.1 - 1.2e-13 50.9 0.1 2.8e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG75327.1 - 1.1e-07 31.7 0.0 2.9e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75327.1 - 1.7e-06 28.6 0.0 3.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75327.1 - 0.00033 21.2 0.7 0.00091 19.7 0.0 2.2 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG75327.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG75327.1 - 0.0042 16.8 0.0 0.0042 16.8 0.0 3.2 3 0 0 3 3 3 1 Phage capsid scaffolding protein (GPO) serine peptidase Asp_protease PF09668.10 GBG75327.1 - 0.0051 16.6 0.0 0.062 13.1 0.0 2.5 1 1 1 2 2 2 1 Aspartyl protease Sirohm_synth_M PF14824.6 GBG75327.1 - 0.2 11.1 0.1 0.49 9.9 0.1 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Integrase_H2C2 PF17921.1 GBG75328.1 - 2.6e-18 65.9 0.4 5.8e-18 64.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75328.1 - 9.4e-16 58.1 0.0 4.8e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG75328.1 - 2.8e-13 50.0 1.0 5.3e-13 49.2 1.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75328.1 - 2.5e-07 30.7 0.3 4.6e-07 29.8 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG75328.1 - 0.012 15.8 0.1 0.039 14.2 0.1 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Ribosomal_S7 PF00177.21 GBG75329.1 - 0.021 14.5 0.3 0.023 14.4 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e GDE_N PF12439.8 GBG75329.1 - 0.092 12.2 0.3 0.09 12.2 0.3 1.0 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal RVT_1 PF00078.27 GBG75330.1 - 2.6e-08 33.7 0.0 5.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG75330.1 - 2.8e-05 23.9 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG75330.1 - 0.00026 21.5 0.1 0.00059 20.3 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG75330.1 - 0.00033 20.4 0.1 0.0039 17.0 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG75330.1 - 0.0012 19.5 0.0 0.0024 18.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease FRQ PF09421.10 GBG75330.1 - 1.4 6.9 6.1 1.9 6.4 6.1 1.1 1 0 0 1 1 1 0 Frequency clock protein BUD22 PF09073.10 GBG75330.1 - 4.9 6.4 15.4 8.4 5.6 15.4 1.2 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 GBG75330.1 - 7.3 5.9 16.9 2.3 7.6 13.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Mpp10 PF04006.12 GBG75330.1 - 9.9 4.5 23.9 5.6 5.3 0.1 2.1 2 0 0 2 2 2 0 Mpp10 protein RVT_1 PF00078.27 GBG75331.1 - 1.4e-34 119.5 0.1 2.5e-34 118.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75331.1 - 2e-15 56.6 0.1 1.1e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG75331.1 - 1e-09 38.6 0.0 3e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG75331.1 - 0.0015 18.8 0.3 0.0035 17.6 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG75331.1 - 0.002 18.3 0.0 0.0069 16.6 0.0 2.0 2 0 0 2 2 2 1 H2C2 zinc finger eIF-1a PF01176.19 GBG75331.1 - 0.025 14.4 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 CCD48 PF15799.5 GBG75331.1 - 0.077 11.3 2.5 0.12 10.6 2.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 GIT_CC PF16559.5 GBG75331.1 - 0.09 12.7 4.7 3.2 7.7 1.0 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2385 PF09539.10 GBG75331.1 - 0.12 12.9 0.1 2 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) DivIC PF04977.15 GBG75331.1 - 0.17 11.7 1.4 0.66 9.8 1.4 2.0 1 0 0 1 1 1 0 Septum formation initiator zf-CCHC PF00098.23 GBG75332.1 - 6.8e-09 35.4 1.5 1.6e-08 34.2 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG75332.1 - 0.00023 20.9 2.1 0.00049 19.9 2.0 1.7 2 0 0 2 2 2 1 Zinc knuckle HTH_32 PF13565.6 GBG75332.1 - 0.012 16.2 0.0 2 9.1 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain BUD22 PF09073.10 GBG75332.1 - 3.6 6.8 13.0 7.1 5.9 6.6 2.1 2 0 0 2 2 2 0 BUD22 DUF659 PF04937.15 GBG75333.1 - 3.3e-31 108.2 0.2 5.3e-31 107.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG75333.1 - 1.7e-13 50.8 0.0 7.7e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG75333.1 - 5.8e-07 29.5 0.3 9e-06 25.7 0.0 2.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 GBG75333.1 - 0.0077 16.0 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG75333.1 - 0.045 14.4 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease D5_N PF08706.11 GBG75335.1 - 0.74 10.1 11.4 0.89 9.8 11.4 1.2 1 0 0 1 1 1 0 D5 N terminal like GAGA_bind PF06217.12 GBG75335.1 - 1.3 9.2 20.3 1.6 9.0 20.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3807 PF12720.7 GBG75335.1 - 1.4 9.2 26.0 1.8 8.8 26.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) YqfQ PF14181.6 GBG75335.1 - 1.6 8.9 19.9 1.8 8.7 19.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein Vfa1 PF08432.10 GBG75335.1 - 2.5 8.4 29.7 3.1 8.1 29.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_polI_A34 PF08208.11 GBG75335.1 - 2.9 7.9 38.0 3.7 7.6 38.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 LicD PF04991.13 GBG75335.1 - 3.2 7.8 14.1 3.7 7.6 14.1 1.1 1 0 0 1 1 1 0 LicD family DDHD PF02862.17 GBG75335.1 - 3.8 7.6 10.5 4.4 7.4 10.5 1.2 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 GBG75335.1 - 4.4 5.5 26.6 5.2 5.2 26.6 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG75335.1 - 4.5 7.0 25.0 5.4 6.8 25.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3405 PF11885.8 GBG75335.1 - 5.8 5.4 16.6 6.2 5.3 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) SelP_N PF04592.14 GBG75335.1 - 6.4 6.1 14.3 8.1 5.8 14.3 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2828 PF11443.8 GBG75335.1 - 7 4.6 17.7 7.4 4.5 17.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RVT_1 PF00078.27 GBG75336.1 - 9.2e-26 90.7 0.1 1.4e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG75337.1 - 2.5e-16 59.9 0.0 4.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ARGLU PF15346.6 GBG75337.1 - 0.33 10.8 20.7 0.56 10.1 20.7 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DDRGK PF09756.9 GBG75337.1 - 0.34 10.5 14.7 0.55 9.8 14.7 1.2 1 0 0 1 1 1 0 DDRGK domain RVT_1 PF00078.27 GBG75338.1 - 1.2e-20 74.0 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75338.1 - 2.1e-17 63.0 0.0 5.4e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75338.1 - 1.5e-08 34.9 0.0 3.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG75338.1 - 0.0032 16.7 0.1 0.0094 15.1 0.0 1.6 1 1 1 2 2 2 1 Autophagy protein Apg17 zf-RING_2 PF13639.6 GBG75339.1 - 9.6e-11 41.8 5.6 9.6e-11 41.8 5.6 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG75339.1 - 3.3e-09 36.4 4.0 6.7e-09 35.4 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG75339.1 - 2.2e-07 31.1 9.3 8.4e-07 29.2 9.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GBG75339.1 - 3.2e-07 30.1 2.9 6.5e-07 29.1 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG75339.1 - 7.8e-07 29.0 4.1 2.2e-06 27.6 4.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 GBG75339.1 - 1.3e-06 28.0 1.1 2.2e-06 27.3 0.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 GBG75339.1 - 1e-05 25.4 3.0 2e-05 24.4 3.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GBG75339.1 - 2.2e-05 24.2 2.6 4.8e-05 23.1 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GBG75339.1 - 0.0037 17.3 2.7 0.012 15.7 2.1 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 GBG75339.1 - 0.0056 16.8 3.2 0.013 15.6 3.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GBG75339.1 - 0.0075 16.1 4.2 0.0075 16.1 4.2 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 GBG75339.1 - 0.012 15.5 0.2 0.036 13.9 0.2 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_10 PF16685.5 GBG75339.1 - 0.03 14.5 1.8 0.03 14.5 1.8 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 GBG75339.1 - 0.079 12.6 6.1 0.17 11.6 6.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 GBG75339.1 - 0.22 11.4 3.0 0.39 10.6 3.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Phlebovirus_NSM PF07246.11 GBG75341.1 - 0.0019 17.6 0.7 0.0032 16.9 0.7 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M Cnn_1N PF07989.11 GBG75341.1 - 0.012 15.7 0.3 0.026 14.7 0.3 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 GBG75341.1 - 0.032 14.3 3.6 0.075 13.1 3.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor GAS PF13851.6 GBG75341.1 - 0.048 13.0 3.2 0.079 12.3 3.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IFP_35_N PF07334.13 GBG75341.1 - 0.074 13.1 0.2 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus UPF0242 PF06785.11 GBG75341.1 - 0.16 12.1 2.4 0.23 11.5 2.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Shugoshin_N PF07558.11 GBG75341.1 - 0.26 11.2 4.2 0.88 9.5 0.8 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region HTH_Tnp_IS630 PF01710.16 GBG75341.1 - 0.39 10.8 1.7 10 6.2 0.0 3.1 3 0 0 3 3 3 0 Transposase Med21 PF11221.8 GBG75341.1 - 5.6 7.2 8.1 1 9.6 4.1 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Phlebovirus_NSM PF07246.11 GBG75342.1 - 0.0014 18.0 0.5 0.0022 17.5 0.5 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M Cnn_1N PF07989.11 GBG75342.1 - 0.0097 16.0 0.3 0.021 15.0 0.3 1.5 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 GBG75342.1 - 0.026 14.6 3.6 0.06 13.4 3.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor GAS PF13851.6 GBG75342.1 - 0.038 13.3 3.2 0.063 12.6 3.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IFP_35_N PF07334.13 GBG75342.1 - 0.06 13.4 0.2 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus UPF0242 PF06785.11 GBG75342.1 - 0.12 12.4 2.3 0.17 12.0 2.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FAM104 PF15434.6 GBG75342.1 - 0.16 12.6 0.8 0.74 10.4 0.2 2.3 2 0 0 2 2 2 0 Family 104 Shugoshin_N PF07558.11 GBG75342.1 - 0.17 11.8 4.2 0.71 9.8 0.8 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region HEXIM PF15313.6 GBG75342.1 - 0.17 12.0 0.0 0.17 12.0 0.0 2.1 2 1 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein HTH_Tnp_IS630 PF01710.16 GBG75342.1 - 0.21 11.6 1.6 8.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Transposase Med21 PF11221.8 GBG75342.1 - 5.6 7.2 8.6 0.81 9.9 4.1 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex CCDC-167 PF15188.6 GBG75342.1 - 9.8 6.6 7.9 3.5 8.0 3.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 RT_RNaseH_2 PF17919.1 GBG75344.1 - 1.5e-29 101.9 0.0 8.5e-15 54.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75344.1 - 1.5e-27 96.0 0.0 3.5e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75344.1 - 3.2e-25 89.0 0.0 5.3e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75344.1 - 1.1e-12 47.9 0.7 2.6e-12 46.7 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG75344.1 - 3.1e-12 46.2 0.0 6.2e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG75344.1 - 0.017 15.3 0.1 0.042 14.1 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_3 PF13456.6 GBG75344.1 - 0.13 12.0 0.5 0.75 9.6 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like DUF4399 PF14347.6 GBG75344.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) DUF659 PF04937.15 GBG75345.1 - 3.2e-32 111.5 0.0 5.5e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG75345.1 - 0.0005 19.8 1.1 0.0011 18.7 0.3 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Glyco_hydro_79n PF03662.14 GBG75345.1 - 0.0042 16.1 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain RNA_pol_3_Rpc31 PF11705.8 GBG75345.1 - 0.24 11.6 10.9 0.43 10.8 10.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.19 GBG75345.1 - 0.45 11.1 4.3 0.94 10.1 4.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Phage_Gp23 PF10669.9 GBG75346.1 - 6.4 7.1 5.2 11 6.4 5.2 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Gb3_synth PF04572.12 GBG75348.1 - 1.5e-17 64.0 0.4 5.2e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 GBG75348.1 - 1.1e-16 61.2 0.0 2.6e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Raptor_N PF14538.6 GBG75348.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain APOBEC_N PF08210.11 GBG75348.1 - 0.053 13.4 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF659 PF04937.15 GBG75349.1 - 2.3e-35 121.7 0.1 4e-35 120.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG75349.1 - 0.036 14.1 1.0 0.071 13.1 0.4 1.8 2 0 0 2 2 2 0 BED zinc finger Antigen_Bd37 PF11641.8 GBG75349.1 - 0.055 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein RVT_1 PF00078.27 GBG75350.1 - 2.7e-18 66.3 0.1 8.9e-18 64.6 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Viral_Hsp90 PF03225.14 GBG75350.1 - 0.084 11.4 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Vac_Fusion PF02346.16 GBG75350.1 - 0.14 11.8 0.4 1.6 8.4 0.5 2.6 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Gb3_synth PF04572.12 GBG75351.1 - 1.9e-16 60.4 2.8 1.2e-10 41.7 0.0 2.4 2 0 0 2 2 2 2 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 GBG75351.1 - 1.4e-14 54.5 0.0 3.9e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 GBG75352.1 - 3e-19 69.5 3.5 5.4e-11 42.8 0.1 3.0 4 0 0 4 4 4 2 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 GBG75352.1 - 6.4e-14 52.4 0.0 1.3e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif APOBEC_N PF08210.11 GBG75352.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain RT_RNaseH_2 PF17919.1 GBG75356.1 - 1.3e-34 118.3 0.0 6.3e-34 116.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75356.1 - 3.9e-29 101.0 0.0 1.1e-28 99.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75356.1 - 2.3e-15 56.8 0.0 9.3e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG75356.1 - 0.00043 20.2 1.1 0.0013 18.7 1.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG75356.1 - 1.6 9.0 3.7 3.8 7.8 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Peptidase_M50 PF02163.22 GBG75357.1 - 2.2e-08 33.7 0.0 2.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M50 Myb_DNA-bind_4 PF13837.6 GBG75357.1 - 5.6e-08 33.1 2.0 1e-07 32.2 2.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PDZ_2 PF13180.6 GBG75357.1 - 0.0013 19.0 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Retrotrans_gag PF03732.17 GBG75358.1 - 0.0082 16.4 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein API5 PF05918.11 GBG75358.1 - 1.9 7.2 5.9 5.9 5.6 3.3 2.5 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) RT_RNaseH PF17917.1 GBG75359.1 - 4.1e-22 78.5 0.0 8.3e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75359.1 - 2.8e-20 72.2 0.0 5.2e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75359.1 - 8.8e-09 35.2 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75359.1 - 2.1e-08 34.2 0.0 4.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Peptidase_M50 PF02163.22 GBG75361.1 - 3.1e-09 36.5 0.0 4.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 GBG75361.1 - 0.0019 18.5 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Big_11 PF18200.1 GBG75362.1 - 0.21 11.5 5.2 5.5 7.0 0.2 3.1 2 1 1 3 3 3 0 Bacterial Ig-like domain Keratin PF02422.16 GBG75362.1 - 0.37 10.5 2.5 0.67 9.7 1.2 2.0 2 0 0 2 2 2 0 Keratin DUF3153 PF11353.8 GBG75366.1 - 0.16 11.5 0.9 0.34 10.5 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) CENP-F_leu_zip PF10473.9 GBG75366.1 - 9.9 6.2 16.4 0.042 13.9 2.2 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RT_RNaseH PF17917.1 GBG75367.1 - 2.5e-22 79.1 0.0 1e-21 77.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75367.1 - 1.7e-19 69.7 0.0 5.2e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1002 PF06207.11 GBG75367.1 - 0.26 10.8 2.1 0.65 9.5 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) gag-asp_proteas PF13975.6 GBG75368.1 - 0.0082 16.7 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG75368.1 - 0.092 13.1 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75368.1 - 0.11 13.1 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG75368.1 - 0.11 12.6 0.7 0.34 11.0 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle CPSF100_C PF13299.6 GBG75369.1 - 0.001 19.3 2.8 0.0012 19.0 2.8 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal SDA1 PF05285.12 GBG75369.1 - 0.0011 18.5 14.6 0.0012 18.4 14.6 1.0 1 0 0 1 1 1 1 SDA1 DNA_pol_phi PF04931.13 GBG75369.1 - 0.0022 16.2 20.3 0.0025 16.0 20.3 1.0 1 0 0 1 1 1 1 DNA polymerase phi Mpp10 PF04006.12 GBG75369.1 - 0.0053 15.3 15.3 0.0058 15.1 15.3 1.0 1 0 0 1 1 1 1 Mpp10 protein PI3K_1B_p101 PF10486.9 GBG75369.1 - 0.0063 14.4 3.4 0.0076 14.1 3.4 1.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BUD22 PF09073.10 GBG75369.1 - 0.013 14.9 11.9 0.014 14.8 11.9 1.0 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 GBG75369.1 - 0.015 15.7 6.3 0.018 15.4 6.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SpoIIP PF07454.11 GBG75369.1 - 0.027 13.9 4.5 0.029 13.8 4.5 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4471 PF14740.6 GBG75369.1 - 0.03 13.5 0.4 0.029 13.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF4637 PF15470.6 GBG75369.1 - 0.041 13.6 14.8 0.053 13.2 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Prothymosin PF03247.14 GBG75369.1 - 0.054 14.0 34.6 0.075 13.5 34.6 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family DDRGK PF09756.9 GBG75369.1 - 0.055 13.1 18.7 0.067 12.8 18.7 1.1 1 0 0 1 1 1 0 DDRGK domain FmiP_Thoc5 PF09766.9 GBG75369.1 - 0.083 12.2 5.2 0.096 11.9 5.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Nop14 PF04147.12 GBG75369.1 - 0.097 10.9 20.0 0.11 10.7 20.0 1.0 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 GBG75369.1 - 0.13 12.4 1.8 0.16 12.1 1.8 1.1 1 0 0 1 1 1 0 DDHD domain DUF3391 PF11871.8 GBG75369.1 - 0.15 12.6 5.9 0.19 12.3 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Eapp_C PF10238.9 GBG75369.1 - 0.19 11.8 4.4 0.22 11.6 4.4 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein TRAP_alpha PF03896.16 GBG75369.1 - 0.19 10.9 11.3 0.23 10.7 11.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MRNIP PF15749.5 GBG75369.1 - 0.26 12.0 4.8 0.31 11.8 4.8 1.2 1 0 0 1 1 1 0 MRN-interacting protein Tim54 PF11711.8 GBG75369.1 - 0.29 9.9 8.9 0.35 9.6 8.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 XAP5 PF04921.14 GBG75369.1 - 0.3 10.9 8.1 0.35 10.7 8.1 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Connexin PF00029.19 GBG75369.1 - 0.34 10.6 6.3 0.42 10.3 6.3 1.1 1 0 0 1 1 1 0 Connexin FYDLN_acid PF09538.10 GBG75369.1 - 0.35 11.6 12.5 0.47 11.2 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Mem_trans PF03547.18 GBG75369.1 - 0.39 9.0 1.3 0.46 8.8 1.3 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4366 PF14283.6 GBG75369.1 - 0.41 10.7 9.4 0.88 9.6 9.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Sporozoite_P67 PF05642.11 GBG75369.1 - 0.45 8.5 8.1 0.61 8.1 8.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF913 PF06025.12 GBG75369.1 - 0.6 9.0 5.7 0.72 8.8 5.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3306 PF11748.8 GBG75369.1 - 0.71 10.8 8.3 0.9 10.4 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) MDM31_MDM32 PF08118.11 GBG75369.1 - 0.72 8.4 2.7 0.92 8.1 2.7 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins CbtA PF09490.10 GBG75369.1 - 0.75 9.5 2.7 0.92 9.2 2.7 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) CDC27 PF09507.10 GBG75369.1 - 0.75 9.1 13.5 0.92 8.8 13.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RAB3GAP2_C PF14656.6 GBG75369.1 - 0.76 7.9 5.7 0.88 7.7 5.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RPA43_OB PF17875.1 GBG75369.1 - 0.81 10.3 7.2 1.1 9.9 7.2 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RXT2_N PF08595.11 GBG75369.1 - 0.86 9.6 11.8 1.2 9.2 11.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Presenilin PF01080.17 GBG75369.1 - 0.88 8.3 6.5 1 8.0 6.5 1.1 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 GBG75369.1 - 0.92 9.2 5.1 1.1 8.9 5.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Sec62 PF03839.16 GBG75369.1 - 1 8.8 3.8 1.2 8.6 3.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 GBG75369.1 - 1.1 8.4 4.8 1.3 8.2 4.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cytomega_UL84 PF06284.11 GBG75369.1 - 1.1 7.6 6.3 1.3 7.4 6.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF5523 PF17661.1 GBG75369.1 - 1.4 8.6 19.4 1.7 8.3 19.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) PTPRCAP PF15713.5 GBG75369.1 - 1.5 9.1 21.0 2 8.7 21.0 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Sigma70_ner PF04546.13 GBG75369.1 - 1.5 8.6 17.3 1.9 8.3 17.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Afi1 PF07792.12 GBG75369.1 - 1.7 9.1 8.5 2.2 8.8 8.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pox_Ag35 PF03286.14 GBG75369.1 - 1.9 8.2 16.1 2.5 7.8 16.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RPN2_C PF18004.1 GBG75369.1 - 2.1 8.3 17.8 2.8 7.8 17.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain THOC2_N PF16134.5 GBG75369.1 - 2.2 6.8 6.0 2.6 6.6 6.0 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus RNA_pol_Rpc4 PF05132.14 GBG75369.1 - 2.2 8.7 8.2 2.9 8.3 8.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 ORC_WH_C PF18137.1 GBG75369.1 - 2.7 8.1 13.2 3.5 7.7 13.2 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal MCM_bind PF09739.9 GBG75369.1 - 3 6.2 5.3 3.4 6.0 5.3 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDC45 PF02724.14 GBG75369.1 - 3.3 5.9 17.0 4.1 5.6 17.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 GBG75369.1 - 3.9 6.8 11.1 5.7 6.2 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4746 PF15928.5 GBG75369.1 - 5.3 6.4 22.3 7.1 6.0 22.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DARPP-32 PF05395.12 GBG75369.1 - 5.4 7.2 18.1 8 6.7 18.1 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Nop53 PF07767.11 GBG75369.1 - 6.6 6.0 22.3 8.2 5.7 22.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 GBG75369.1 - 8.3 6.1 16.7 10 5.8 16.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 GBG75369.1 - 9 5.6 24.1 12 5.2 24.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT N6_N4_Mtase PF01555.18 GBG75370.1 - 2.5e-10 40.4 0.0 6.8e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 DNA methylase DUF659 PF04937.15 GBG75371.1 - 1.5e-20 73.6 0.0 2.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG75371.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RRM_1 PF00076.22 GBG75372.1 - 6.5e-11 41.9 0.0 9.3e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG75372.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Ribosomal_S10 PF00338.22 GBG75373.1 - 1.4e-30 105.4 0.2 1.7e-30 105.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e NUDIX PF00293.28 GBG75374.1 - 0.00017 21.6 1.1 0.00042 20.4 1.1 1.6 1 0 0 1 1 1 1 NUDIX domain RRN9 PF10680.9 GBG75374.1 - 0.41 11.0 2.1 16 5.9 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor PT-VENN PF04829.13 GBG75374.1 - 2.1 8.5 4.1 15 5.8 0.0 2.9 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Phage_lysozyme PF00959.19 GBG75375.1 - 0.12 12.9 1.1 13 6.3 0.1 2.6 2 0 0 2 2 2 0 Phage lysozyme ABATE PF07336.11 GBG75375.1 - 7.4 7.2 9.6 1.6 9.4 0.5 2.9 2 1 0 2 2 2 0 Putative stress-induced transcription regulator MACPF PF01823.19 GBG75376.1 - 3.4e-21 76.3 0.0 6.1e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain Neuropeptide_S PF14993.6 GBG75377.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Neuropeptide S precursor protein CBS PF00571.28 GBG75378.1 - 1.3e-23 83.2 2.5 1.6e-12 47.6 0.2 2.5 2 0 0 2 2 2 2 CBS domain PRC PF05239.16 GBG75378.1 - 0.00026 21.0 0.1 0.0092 16.0 0.0 2.8 2 0 0 2 2 2 1 PRC-barrel domain PcrB PF01884.17 GBG75378.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 PcrB family PikAIV_N PF18605.1 GBG75379.1 - 0.0002 20.9 2.8 0.16 11.6 1.0 3.3 2 0 0 2 2 2 2 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DivIC PF04977.15 GBG75379.1 - 0.023 14.5 0.6 0.023 14.5 0.6 4.4 3 1 1 4 4 4 0 Septum formation initiator SlyX PF04102.12 GBG75379.1 - 0.092 13.4 0.1 0.092 13.4 0.1 4.5 4 1 1 5 5 5 0 SlyX PhoU PF01895.19 GBG75379.1 - 0.12 12.9 6.0 4.6 7.8 0.1 3.1 2 2 0 2 2 2 0 PhoU domain Presenilin PF01080.17 GBG75379.1 - 5.6 5.6 8.7 8.4 5.0 8.7 1.4 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG75381.1 - 2e-28 99.5 0.1 4.6e-28 98.2 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75381.1 - 1.8e-25 88.8 0.0 6.1e-25 87.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75381.1 - 3.8e-23 81.8 0.0 1.2e-22 80.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75381.1 - 2.5e-18 65.9 0.3 1.1e-17 63.9 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG75381.1 - 9e-07 29.1 0.0 3.4e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG75381.1 - 6.7e-05 23.1 1.4 0.14 12.4 0.0 4.0 3 0 0 3 3 3 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG75381.1 - 0.064 13.5 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger CLZ PF16526.5 GBG75381.1 - 5.6 7.4 9.7 1.4 9.4 0.4 4.2 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Peptidase_M20 PF01546.28 GBG75382.1 - 7.9e-26 91.0 0.1 1.4e-24 87.0 0.0 2.6 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GBG75382.1 - 1.9e-07 31.0 0.3 5.2e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain DUF167 PF02594.16 GBG75382.1 - 0.12 12.5 0.1 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised ACR, YggU family COG1872 Fib_alpha PF08702.10 GBG75383.1 - 0.16 12.1 1.8 0.29 11.3 1.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RNA_polI_A14 PF08203.11 GBG75383.1 - 3.4 8.5 4.7 5.8 7.7 0.0 3.3 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 RNA_pol_Rpb8 PF03870.15 GBG75384.1 - 8.9e-23 81.0 0.0 9.8e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 O-FucT PF10250.9 GBG75385.1 - 9.8e-15 55.1 0.0 3.8e-13 49.9 0.0 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Hist_deacetyl PF00850.19 GBG75386.1 - 7.9e-87 291.6 0.0 1e-86 291.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Clathrin PF00637.20 GBG75387.1 - 7.8e-21 74.4 2.2 1.1e-13 51.3 0.7 3.0 2 1 1 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.8 GBG75387.1 - 5e-15 55.4 0.2 1.1e-14 54.3 0.2 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 GBG75387.1 - 1.5e-05 24.9 8.7 3.3e-05 23.8 8.7 1.6 1 0 0 1 1 1 1 Zinc-finger zf-RING_6 PF14835.6 GBG75387.1 - 7.4e-05 22.5 1.1 0.00015 21.6 1.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 GBG75387.1 - 0.0011 18.8 9.4 0.0023 17.7 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG75387.1 - 0.0037 17.6 8.8 0.0078 16.5 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG75387.1 - 0.0063 16.4 7.0 0.013 15.4 7.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain GDE_C PF06202.14 GBG75387.1 - 0.008 15.2 0.0 0.046 12.7 0.0 1.9 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Vps8 PF12816.7 GBG75387.1 - 0.013 15.1 0.2 0.23 11.0 0.0 2.4 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 TPR_11 PF13414.6 GBG75387.1 - 0.16 11.7 1.9 0.21 11.3 0.2 2.1 2 0 0 2 2 2 0 TPR repeat zf-rbx1 PF12678.7 GBG75387.1 - 0.25 11.7 7.0 0.52 10.6 7.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GBG75387.1 - 1.1 9.4 9.9 2.5 8.2 9.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger TPR_2 PF07719.17 GBG75387.1 - 1.4 9.3 4.9 18 5.8 0.1 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG75387.1 - 2.3 8.6 12.1 0.52 10.6 0.1 4.4 5 1 1 6 6 5 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 GBG75387.1 - 6.7 6.7 8.2 14 5.6 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BTB PF00651.31 GBG75388.1 - 7.7e-17 61.5 0.1 1.3e-16 60.8 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 GBG75388.1 - 0.005 16.9 1.1 1.4 9.1 0.0 2.6 3 0 0 3 3 3 2 BTB And C-terminal Kelch MttA_Hcf106 PF02416.16 GBG75391.1 - 7.1e-21 73.3 0.1 9.2e-21 72.9 0.1 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family YtxH PF12732.7 GBG75391.1 - 0.00082 19.9 1.4 0.0011 19.4 1.4 1.1 1 0 0 1 1 1 1 YtxH-like protein eIF-3_zeta PF05091.12 GBG75392.1 - 2.1e-204 680.3 0.0 2.4e-204 680.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 GBG75392.1 - 1.4e-06 28.0 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus RT_RNaseH PF17917.1 GBG75393.1 - 2.6e-27 95.2 0.0 5.7e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75393.1 - 4.6e-21 74.7 0.0 1.1e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75393.1 - 5.2e-20 71.3 0.5 1.4e-19 70.0 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG75393.1 - 0.00016 21.8 0.1 0.00045 20.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG75393.1 - 0.017 14.8 0.1 0.017 14.8 0.1 3.2 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG75394.1 - 2.7e-35 120.4 0.1 5.1e-35 119.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75394.1 - 1.1e-31 109.2 0.1 2.1e-31 108.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75394.1 - 1.4e-28 99.9 0.1 2.4e-28 99.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75394.1 - 1.2e-19 70.2 0.1 2.6e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF5095 PF17016.5 GBG75394.1 - 0.14 11.9 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) RT_RNaseH_2 PF17919.1 GBG75395.1 - 7.9e-29 99.7 0.1 3.4e-28 97.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75395.1 - 3e-24 85.3 1.2 5.4e-24 84.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75395.1 - 2.5e-18 66.4 0.0 6.5e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG75395.1 - 0.00089 19.8 0.2 0.0041 17.7 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG75395.1 - 0.0051 17.0 0.4 0.0051 17.0 0.4 3.7 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG75395.1 - 0.0073 16.9 0.0 0.021 15.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease CRT10 PF08728.10 GBG75395.1 - 0.98 7.5 6.3 1.6 6.8 6.3 1.2 1 0 0 1 1 1 0 CRT10 Cwf_Cwc_15 PF04889.12 GBG75396.1 - 0.0022 17.8 24.7 0.0022 17.8 24.7 2.9 3 0 0 3 3 3 2 Cwf15/Cwc15 cell cycle control protein CENP-Q PF13094.6 GBG75396.1 - 0.059 13.6 4.8 0.18 12.0 4.8 1.8 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Apt1 PF10351.9 GBG75396.1 - 0.33 9.8 6.7 0.5 9.2 6.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPR3 PF03666.13 GBG75396.1 - 0.51 9.1 12.9 0.81 8.4 12.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Plasmodium_Vir PF05795.11 GBG75396.1 - 0.6 9.5 3.0 0.98 8.8 3.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mito_fiss_reg PF05308.11 GBG75396.1 - 4.1 7.4 6.7 41 4.1 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial fission regulator SARAF PF06682.12 GBG75396.1 - 5.5 6.5 9.3 0.36 10.4 3.9 1.8 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF659 PF04937.15 GBG75397.1 - 6.5e-06 26.1 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG75399.1 - 1.5e-05 25.1 0.1 4e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG75399.1 - 0.0087 15.8 3.3 0.01 15.6 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) TolA_bind_tri PF16331.5 GBG75399.1 - 0.19 11.8 1.1 0.45 10.6 1.1 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF1360 PF07098.11 GBG75400.1 - 0.035 14.1 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) RVT_1 PF00078.27 GBG75401.1 - 2e-08 34.0 0.0 3.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG75401.1 - 4.8e-06 27.0 0.1 2.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75401.1 - 0.00036 21.1 0.0 0.0012 19.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG75401.1 - 0.0023 18.0 0.0 0.006 16.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75401.1 - 0.0074 16.6 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG75401.1 - 0.013 15.3 0.8 0.049 13.4 0.2 2.1 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC PF00098.23 GBG75401.1 - 0.017 15.2 1.4 0.043 13.9 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle F-box PF00646.33 GBG75402.1 - 1.6e-06 27.9 1.0 3.2e-06 26.9 0.3 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GBG75402.1 - 1.9e-05 24.5 0.5 4.1e-05 23.4 0.5 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GBG75402.1 - 0.0025 18.2 0.1 3.3 8.3 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG75402.1 - 0.061 13.4 0.4 30 5.0 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat HECT PF00632.25 GBG75402.1 - 0.19 11.2 0.0 1.1 8.7 0.0 1.9 2 0 0 2 2 2 0 HECT-domain (ubiquitin-transferase) F-box PF00646.33 GBG75403.1 - 1.4e-06 28.0 2.2 2.8e-06 27.1 0.2 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GBG75403.1 - 2.5e-05 24.1 0.8 7.3e-05 22.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GBG75403.1 - 0.00012 22.4 0.4 0.03 14.7 0.0 3.9 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 GBG75404.1 - 2.4e-05 24.6 1.3 0.07 13.6 0.0 4.3 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG75404.1 - 0.0028 17.6 0.3 1.2 9.3 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeat LRR_8 PF13855.6 GBG75404.1 - 0.11 12.3 0.4 7.3 6.4 0.0 3.3 4 0 0 4 4 4 0 Leucine rich repeat RT_RNaseH_2 PF17919.1 GBG75405.1 - 3.3e-27 94.5 0.0 6.1e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75405.1 - 2.4e-25 88.9 0.0 4.2e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75405.1 - 5.9e-07 29.2 0.1 9.9e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG75405.1 - 0.0012 18.6 0.0 2.2 8.2 0.0 3.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2249) Nop14 PF04147.12 GBG75405.1 - 0.77 7.9 25.7 1.3 7.2 25.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG75405.1 - 2.5 6.3 19.3 4.2 5.6 19.3 1.3 1 0 0 1 1 1 0 CDC45-like protein PIEZO PF15917.5 GBG75405.1 - 3.1 7.2 6.3 6.2 6.2 6.3 1.5 1 0 0 1 1 1 0 Piezo Presenilin PF01080.17 GBG75405.1 - 6.2 5.5 11.6 9.7 4.8 11.6 1.3 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.12 GBG75405.1 - 7.4 6.2 25.3 64 3.2 24.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Integrase_H2C2 PF17921.1 GBG75406.1 - 3.5e-12 46.2 0.1 7.9e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75406.1 - 2.2e-05 24.6 0.0 4.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG75406.1 - 0.0013 19.3 0.0 0.0032 18.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75406.1 - 0.0084 16.7 0.0 0.019 15.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG75406.1 - 0.12 12.5 0.7 0.36 11.0 0.7 1.9 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG75407.1 - 6.4e-08 32.9 0.5 1.2e-07 32.0 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG75407.1 - 0.011 15.9 0.3 0.031 14.4 0.3 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG75407.1 - 0.061 13.7 0.5 0.12 12.7 0.5 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like F-box PF00646.33 GBG75408.1 - 2.8e-07 30.2 3.1 9.5e-07 28.6 3.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG75408.1 - 5.1e-06 26.3 4.5 1.3e-05 24.9 4.5 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GBG75408.1 - 0.01 16.3 0.3 0.25 11.8 0.0 3.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG75408.1 - 0.22 11.7 0.9 39 4.7 0.0 3.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 GBG75408.1 - 0.24 11.2 1.8 25 4.7 0.1 3.3 2 2 1 3 3 3 0 Leucine rich repeat CNDH2_M PF16869.5 GBG75411.1 - 0.062 14.0 2.0 0.18 12.5 2.0 1.8 1 0 0 1 1 1 0 PF16858 CitMHS PF03600.16 GBG75411.1 - 4.1 6.5 34.2 5.1 6.2 34.2 1.1 1 0 0 1 1 1 0 Citrate transporter Nucleotid_trans PF03407.16 GBG75412.1 - 1.4e-16 61.1 0.0 1.9e-07 31.3 0.0 2.6 2 1 0 2 2 2 2 Nucleotide-diphospho-sugar transferase RasGEF_N PF00618.20 GBG75413.1 - 0.17 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 RasGEF N-terminal motif Presenilin PF01080.17 GBG75413.1 - 9.6 4.9 11.0 21 3.7 11.0 1.5 1 1 0 1 1 1 0 Presenilin TTSSLRR PF12468.8 GBG75414.1 - 0.0022 18.2 0.0 0.006 16.8 0.0 1.7 1 0 0 1 1 1 1 Type III secretion system leucine rich repeat protein Cornifin PF02389.15 GBG75416.1 - 0.0064 16.7 2.8 0.0088 16.2 2.8 1.2 1 0 0 1 1 1 1 Cornifin (SPRR) family Glyco_hydro_3 PF00933.21 GBG75419.1 - 5.2e-74 249.5 0.0 6.7e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain rve PF00665.26 GBG75420.1 - 1.5e-06 28.4 0.1 3.8e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG75420.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TMEM247 PF15444.6 GBG75420.1 - 0.019 15.0 0.1 0.019 15.0 0.1 2.5 3 0 0 3 3 3 0 Transmembrane protein 247 CENP-K PF11802.8 GBG75420.1 - 0.32 10.5 5.2 0.67 9.5 5.2 1.4 1 0 0 1 1 1 0 Centromere-associated protein K Hid1 PF12722.7 GBG75422.1 - 0.76 7.8 5.4 0.96 7.5 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Myb_DNA-bind_4 PF13837.6 GBG75423.1 - 0.012 16.0 6.5 0.022 15.1 6.5 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Sporozoite_P67 PF05642.11 GBG75423.1 - 0.11 10.6 7.5 0.14 10.2 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RT_RNaseH PF17917.1 GBG75425.1 - 8.9e-21 74.2 0.0 1.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75425.1 - 4.8e-18 65.1 0.0 7.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75425.1 - 3.1e-14 52.8 0.1 7.3e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75425.1 - 2.8e-09 37.2 0.0 5.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG75425.1 - 0.03 14.5 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG75426.1 - 3.4e-05 23.5 0.0 6.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DPBB_1 PF03330.18 GBG75428.1 - 2.5e-13 50.1 0.9 5.2e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG75428.1 - 2.9e-09 36.8 0.0 5.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Pollen allergen Abhydro_lipase PF04083.16 GBG75429.1 - 6.4e-19 67.3 0.0 1.4e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GBG75429.1 - 5.2e-11 42.7 0.1 7e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG75429.1 - 1.5e-07 31.0 0.1 2.2e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG75429.1 - 9.1e-06 26.4 2.2 2e-05 25.3 2.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Swi5 PF07061.11 GBG75429.1 - 0.19 11.9 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Swi5 SpoIIP PF07454.11 GBG75430.1 - 0.016 14.7 2.1 0.026 14.0 0.1 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RNA_polI_A34 PF08208.11 GBG75430.1 - 0.2 11.7 13.8 0.078 13.1 5.1 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 eIF-3c_N PF05470.12 GBG75430.1 - 0.54 8.5 5.3 0.67 8.2 5.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.12 GBG75430.1 - 4.2 6.7 26.0 11 5.3 26.0 1.6 1 1 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG75430.1 - 5.1 5.2 23.4 0.15 10.3 13.5 1.9 2 0 0 2 2 2 0 Nop14-like family SpoIIP PF07454.11 GBG75431.1 - 0.0021 17.6 10.2 0.0026 17.2 10.2 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Hep_59 PF07052.11 GBG75431.1 - 0.014 16.2 12.6 0.014 16.2 12.6 2.1 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 BUD22 PF09073.10 GBG75431.1 - 0.052 12.9 21.7 0.063 12.6 21.7 1.0 1 0 0 1 1 1 0 BUD22 ArAE_2_N PF10337.9 GBG75431.1 - 0.68 8.9 3.5 0.73 8.8 3.5 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Folliculin PF11704.8 GBG75431.1 - 1.1 9.1 10.0 1.4 8.8 9.6 1.4 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport EOS1 PF12326.8 GBG75431.1 - 1.9 8.4 6.0 3.2 7.6 6.0 1.3 1 0 0 1 1 1 0 N-glycosylation protein FHIPEP PF00771.20 GBG75431.1 - 2 6.8 3.9 2.2 6.6 3.9 1.1 1 0 0 1 1 1 0 FHIPEP family EFTUD2 PF16004.5 GBG75431.1 - 2.3 8.8 16.3 0.34 11.5 11.3 2.0 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus V_ATPase_I PF01496.19 GBG75431.1 - 4.2 5.2 9.7 4.2 5.2 9.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 GBG75431.1 - 6.2 5.5 10.8 6.8 5.4 10.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 GBG75431.1 - 8.2 5.1 13.8 9.4 4.9 13.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MDM10 PF12519.8 GBG75431.1 - 9.3 5.0 10.5 10 4.8 10.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 UCH PF00443.29 GBG75434.1 - 1.2e-63 215.0 0.0 1.6e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG75434.1 - 6e-23 81.9 0.0 9.2e-20 71.5 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WRC PF08879.10 GBG75435.1 - 5.5e-17 61.2 52.8 6.1e-10 38.6 4.4 6.2 5 1 1 6 6 6 4 WRC zf-C3Hc3H PF13891.6 GBG75435.1 - 3.1 8.2 18.9 0.17 12.3 0.3 4.2 4 0 0 4 4 4 0 Potential DNA-binding domain Plavaka PF18759.1 GBG75436.1 - 1.4e-24 87.0 0.1 2.7e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 Plavaka transposase GP24_25 PF17388.2 GBG75436.1 - 0.071 13.1 0.5 9.3 6.2 0.1 3.0 3 0 0 3 3 3 0 Tail assembly gene products 24 & 25 WD40 PF00400.32 GBG75437.1 - 4.4e-13 49.5 5.9 3.9e-05 24.3 0.1 5.6 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG75437.1 - 0.0071 16.6 0.0 0.039 14.2 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain VEGF_C PF14554.6 GBG75437.1 - 0.018 15.1 0.1 0.071 13.2 0.1 2.0 1 0 0 1 1 1 0 VEGF heparin-binding domain MULE PF10551.9 GBG75439.1 - 1.5e-20 73.4 0.0 4.9e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG75439.1 - 5.5e-15 55.1 0.7 1.3e-14 53.9 0.7 1.6 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.18 GBG75439.1 - 2.1e-07 30.1 0.0 5.3e-07 28.8 0.0 1.7 2 1 0 2 2 2 1 Transposase, Mutator family WD40 PF00400.32 GBG75440.1 - 4.1e-12 46.4 7.6 7e-06 26.7 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG75440.1 - 5.2e-05 23.5 0.1 0.0031 17.8 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 GBG75442.1 - 3.8e-07 29.9 0.0 6.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Topo_Zn_Ribbon PF08272.11 GBG75442.1 - 0.23 11.2 1.4 0.43 10.3 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like DUF4360 PF14273.6 GBG75443.1 - 2e-47 161.3 1.8 2.3e-47 161.2 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Plasmodium_Vir PF05795.11 GBG75444.1 - 0.2 11.0 0.2 0.35 10.2 0.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SHMT PF00464.19 GBG75447.1 - 9.5e-192 636.9 0.0 1.1e-191 636.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 GBG75447.1 - 0.008 15.4 0.0 0.017 14.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GBG75447.1 - 0.02 14.2 0.0 0.043 13.1 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Ubiq-Cytc-red_N PF09165.10 GBG75447.1 - 0.033 15.0 0.0 0.074 14.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal RVT_1 PF00078.27 GBG75448.1 - 4.6e-14 52.5 0.1 7.5e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG75449.1 - 4.9e-08 32.7 2.1 9.8e-08 31.7 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG75449.1 - 0.00014 21.6 1.4 0.00028 20.6 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG75449.1 - 0.00064 19.5 4.1 0.00066 19.5 1.6 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG75449.1 - 0.04 13.7 0.7 0.077 12.7 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Nop14 PF04147.12 GBG75449.1 - 0.069 11.4 24.5 0.09 11.0 24.5 1.0 1 0 0 1 1 1 0 Nop14-like family Tau95 PF09734.9 GBG75449.1 - 1.4 9.7 3.6 3.6 8.4 3.6 1.6 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain NACHT_N PF17100.5 GBG75449.1 - 2.1 8.1 8.4 6.7 6.5 7.2 2.0 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase CDC27 PF09507.10 GBG75449.1 - 2.8 7.2 24.0 4.5 6.6 24.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4360 PF14273.6 GBG75450.1 - 1.4e-38 132.6 4.9 1.6e-38 132.4 4.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) TraW_N PF12477.8 GBG75450.1 - 0.65 10.0 3.6 1.2 9.2 3.6 1.4 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal DUF4360 PF14273.6 GBG75451.1 - 7.6e-45 153.0 1.1 1.1e-44 152.5 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG75451.1 - 4.6e-31 106.8 0.0 1.1e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75451.1 - 3.5e-30 105.2 0.0 6.4e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75451.1 - 3.3e-27 94.8 0.1 7.3e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG75452.1 - 8.2e-05 22.5 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CDC45 PF02724.14 GBG75452.1 - 6.4 4.9 7.9 12 4.0 7.9 1.4 1 0 0 1 1 1 0 CDC45-like protein FCP1_C PF09309.10 GBG75453.1 - 0.21 11.4 9.0 0.34 10.8 9.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal RVT_1 PF00078.27 GBG75454.1 - 1.1e-36 126.4 0.0 1.8e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YkyA PF10368.9 GBG75454.1 - 0.2 11.3 0.1 0.43 10.2 0.1 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Exo_endo_phos PF03372.23 GBG75455.1 - 2.8e-06 27.0 0.0 5.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family KH_7 PF17214.3 GBG75455.1 - 0.024 14.6 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 KH domain Ubiquitin_4 PF18036.1 GBG75455.1 - 0.04 14.0 0.1 0.086 12.9 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain CDC45 PF02724.14 GBG75456.1 - 0.64 8.3 11.9 1 7.6 11.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Gp_dh_C PF02800.20 GBG75458.1 - 9.4e-70 233.3 0.0 1.3e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG75458.1 - 1.9e-38 130.9 0.0 6.1e-38 129.2 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG75458.1 - 0.0018 18.4 0.1 0.0059 16.7 0.1 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 GBG75458.1 - 0.011 15.7 0.1 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H-binding Radical_SAM PF04055.21 GBG75458.1 - 0.045 14.1 0.0 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 Radical SAM superfamily RT_RNaseH_2 PF17919.1 GBG75459.1 - 2.9e-18 65.8 0.0 5e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75459.1 - 9e-14 51.6 0.0 5.3e-12 46.0 0.0 2.3 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2249 PF10006.9 GBG75459.1 - 0.021 14.7 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Gp_dh_C PF02800.20 GBG75460.1 - 9.4e-70 233.3 0.0 1.3e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG75460.1 - 1.9e-38 130.9 0.0 6.1e-38 129.2 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG75460.1 - 0.0018 18.4 0.1 0.0059 16.7 0.1 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 GBG75460.1 - 0.011 15.7 0.1 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H-binding Radical_SAM PF04055.21 GBG75460.1 - 0.045 14.1 0.0 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 Radical SAM superfamily Myb_DNA-bind_4 PF13837.6 GBG75461.1 - 1e-09 38.6 0.0 4.1e-09 36.7 0.0 2.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG75461.1 - 8e-05 22.9 2.3 0.0013 19.0 0.9 3.1 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG75461.1 - 0.04 14.2 1.1 0.1 12.9 1.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG75461.1 - 0.37 10.9 3.6 0.27 11.3 1.4 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 GBG75461.1 - 0.82 10.7 4.0 0.33 12.0 0.2 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain NB-ARC PF00931.22 GBG75463.1 - 2.8e-40 138.1 0.0 4.1e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 GBG75463.1 - 3e-06 27.2 0.0 9e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GBG75463.1 - 0.00011 22.6 0.1 0.00044 20.7 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG75463.1 - 0.0024 18.1 0.0 0.0092 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GBG75463.1 - 0.014 15.3 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GBG75463.1 - 0.059 13.4 0.2 0.21 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GBG75463.1 - 0.1 12.5 0.0 0.85 9.5 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 GBG75463.1 - 0.1 13.0 0.0 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GBG75463.1 - 0.14 12.7 0.0 0.37 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain GTP1_OBG PF01018.22 GBG75463.1 - 0.22 11.1 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 GTP1/OBG DUF1005 PF06219.12 GBG75464.1 - 6.5e-122 407.7 3.2 8.1e-122 407.4 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1005) Peptidase_C48 PF02902.19 GBG75465.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Ribosomal_L6e PF01159.19 GBG75466.1 - 5e-40 136.5 1.1 8.2e-40 135.8 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 GBG75466.1 - 2e-10 40.8 1.5 2e-10 40.8 1.5 2.8 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain P30 PF07390.11 GBG75466.1 - 0.005 16.9 0.3 0.0088 16.1 0.3 1.3 1 0 0 1 1 1 1 Mycoplasma P30 protein BcrAD_BadFG PF01869.20 GBG75468.1 - 5.7e-38 131.0 2.1 1.1e-33 116.9 1.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family BcrAD_BadFG PF01869.20 GBG75469.1 - 6.2e-38 130.8 2.3 1.1e-33 116.8 1.1 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family TamB PF04357.13 GBG75470.1 - 2.6e-13 50.0 0.0 1.2e-11 44.5 0.0 3.8 3 1 1 4 4 4 1 TamB, inner membrane protein subunit of TAM complex Coilin_N PF15862.5 GBG75470.1 - 7 6.5 8.1 21 4.9 8.1 1.8 1 0 0 1 1 1 0 Coilin N-terminus Pheromone PF08015.11 GBG75471.1 - 4 8.5 13.9 0.77 10.8 6.7 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone Serglycin PF04360.12 GBG75472.1 - 2.4 8.1 4.1 35 4.3 0.1 2.7 2 0 0 2 2 2 0 Serglycin WD40 PF00400.32 GBG75476.1 - 0.00063 20.5 0.5 0.86 10.6 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat PTPRCAP PF15713.5 GBG75476.1 - 0.055 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FTCD_N PF07837.12 GBG75477.1 - 9.8e-41 139.4 0.0 2.9e-40 137.9 0.0 1.9 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain TFIIIC_delta PF12657.7 GBG75477.1 - 1.5e-16 60.9 0.1 7.4e-16 58.6 0.1 2.2 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Agenet PF05641.12 GBG75477.1 - 1.7e-06 28.4 7.3 0.00036 21.0 0.6 3.0 2 0 0 2 2 2 2 Agenet domain WD40 PF00400.32 GBG75477.1 - 1.3e-05 25.9 2.1 1.7 9.7 0.3 4.5 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-TFIIIC PF12660.7 GBG75477.1 - 0.0039 17.1 5.1 0.21 11.5 0.1 2.7 2 0 0 2 2 2 2 Putative zinc-finger of transcription factor IIIC complex MMR_HSR1 PF01926.23 GBG75478.1 - 1.2e-48 163.9 0.7 1.1e-25 90.0 0.1 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 GBG75478.1 - 1.1e-28 99.4 0.1 1.8e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 GBG75478.1 - 1.5e-23 83.0 0.1 2.8e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.16 GBG75478.1 - 2.1e-13 50.1 0.2 2.9e-06 26.8 0.1 2.3 2 0 0 2 2 2 2 AIG1 family GTP_EFTU PF00009.27 GBG75478.1 - 2.3e-12 46.9 0.1 2.4e-08 33.8 0.1 4.6 4 1 0 4 4 4 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GBG75478.1 - 1.7e-10 41.2 0.0 0.0017 18.5 0.1 4.0 2 2 2 4 4 4 3 Dynamin family RsgA_GTPase PF03193.16 GBG75478.1 - 8.9e-07 29.0 0.2 0.15 12.0 0.0 3.6 3 0 0 3 3 3 2 RsgA GTPase Roc PF08477.13 GBG75478.1 - 9.1e-06 25.9 0.2 0.12 12.6 0.1 3.3 3 1 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 GBG75478.1 - 4.5e-05 23.1 0.5 0.00085 18.9 0.2 2.7 2 2 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 GBG75478.1 - 0.00041 20.9 0.0 0.26 11.8 0.0 2.6 2 0 0 2 2 2 1 ABC transporter TniB PF05621.11 GBG75478.1 - 0.00046 19.7 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein SRPRB PF09439.10 GBG75478.1 - 0.0035 16.8 0.0 0.59 9.5 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GBG75478.1 - 0.024 14.3 0.1 4.3 6.9 0.0 2.7 2 1 0 2 2 2 0 Ras family AAA_16 PF13191.6 GBG75478.1 - 0.052 13.9 0.1 1.6 9.0 0.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GBG75478.1 - 0.053 13.8 0.0 6.2 7.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GBG75478.1 - 0.072 12.8 0.0 12 5.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 GBG75478.1 - 0.12 12.8 0.0 2.1 8.8 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Antimicrobial25 PF16839.5 GBG75478.1 - 2.3 8.4 7.4 0.35 11.0 2.0 2.3 2 0 0 2 2 2 0 Nematode antimicrobial peptide PP2 PF14299.6 GBG75479.1 - 6.3e-19 68.5 0.0 9.5e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Phloem protein 2 F-box-like PF12937.7 GBG75479.1 - 2.1e-07 30.7 0.3 4.2e-07 29.7 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG75479.1 - 1.4e-05 24.9 0.1 3.3e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain RNA_pol_3_Rpc31 PF11705.8 GBG75479.1 - 0.00067 20.0 12.5 0.00067 20.0 12.5 1.7 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 GBG75479.1 - 0.017 15.2 9.7 6.9 6.7 0.0 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal SDA1 PF05285.12 GBG75479.1 - 0.18 11.2 20.5 0.079 12.4 16.2 2.0 2 0 0 2 2 2 0 SDA1 Presenilin PF01080.17 GBG75479.1 - 1.4 7.6 7.9 0.7 8.6 2.9 2.0 2 0 0 2 2 2 0 Presenilin CPSF100_C PF13299.6 GBG75479.1 - 1.5 9.0 9.4 0.37 11.0 4.3 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MIF4G_like_2 PF09090.11 GBG75479.1 - 1.7 8.0 7.7 2.1 7.7 5.9 1.9 2 0 0 2 2 2 0 MIF4G like Eapp_C PF10238.9 GBG75479.1 - 3.2 7.8 9.2 13 5.9 5.7 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Sigma70_ner PF04546.13 GBG75479.1 - 6 6.7 20.0 0.16 11.8 11.7 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Coilin_N PF15862.5 GBG75479.1 - 7.5 6.4 10.0 0.54 10.1 3.1 2.3 2 0 0 2 2 2 0 Coilin N-terminus Plavaka PF18759.1 GBG75480.1 - 1.5e-22 80.3 0.6 2.5e-22 79.5 0.6 1.3 1 0 0 1 1 1 1 Plavaka transposase Lipocalin_2 PF08212.12 GBG75481.1 - 2.9e-05 24.0 0.0 0.72 9.8 0.0 3.4 2 1 0 2 2 2 2 Lipocalin-like domain T3SS_basalb_I PF17001.5 GBG75481.1 - 0.02 15.5 2.2 0.055 14.1 2.2 1.8 1 1 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF3562 PF12085.8 GBG75481.1 - 0.044 13.4 0.5 0.71 9.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3562) SEN1_N PF12726.7 GBG75481.1 - 0.28 9.3 1.1 0.39 8.9 1.1 1.2 1 0 0 1 1 1 0 SEN1 N terminal Laminin_I PF06008.14 GBG75481.1 - 0.68 9.6 5.7 1.8 8.2 1.7 2.1 1 1 1 2 2 2 0 Laminin Domain I UPF0181 PF03701.14 GBG75481.1 - 8 6.2 6.4 1.9 8.2 0.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) CENP-B_dimeris PF09026.10 GBG75482.1 - 0.012 16.0 1.3 0.025 15.0 1.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain T3SS_basalb_I PF17001.5 GBG75482.1 - 0.035 14.7 1.5 0.098 13.3 1.0 2.0 1 1 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF2935 PF11155.8 GBG75482.1 - 0.2 12.0 0.2 0.43 10.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Laminin_I PF06008.14 GBG75482.1 - 0.59 9.8 6.9 4.3 7.0 2.8 2.3 1 1 1 2 2 2 0 Laminin Domain I Lipocalin_2 PF08212.12 GBG75484.1 - 8.6e-06 25.7 0.0 0.18 11.7 0.0 3.1 2 1 1 3 3 3 3 Lipocalin-like domain YEATS PF03366.16 GBG75486.1 - 2.9e-33 113.7 0.1 4.6e-33 113.0 0.1 1.3 1 0 0 1 1 1 1 YEATS family DUF2189 PF09955.9 GBG75487.1 - 0.018 15.2 0.6 0.042 14.1 0.6 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) GIY-YIG PF01541.24 GBG75488.1 - 1e-13 51.3 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain IMS PF00817.20 GBG75489.1 - 1.6e-40 138.6 0.0 2.9e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 GBG75489.1 - 4.5e-09 35.7 0.3 1.2e-08 34.4 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 GBG75489.1 - 8.4e-06 25.8 0.0 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif IMS_C PF11799.8 GBG75489.1 - 0.00019 22.1 0.0 0.00036 21.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PrmA PF06325.13 GBG75491.1 - 0.013 14.9 4.7 0.019 14.3 4.7 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-CCHC PF00098.23 GBG75491.1 - 0.037 14.1 1.2 0.078 13.1 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle XRN_M PF17846.1 GBG75491.1 - 3.7 6.4 11.2 6.3 5.6 11.2 1.3 1 0 0 1 1 1 0 Xrn1 helical domain DUF4407 PF14362.6 GBG75491.1 - 7 5.9 12.2 5.5 6.3 10.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Sugar_tr PF00083.24 GBG75492.1 - 3.4e-32 111.9 11.4 1.3e-21 77.1 4.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GBG75492.1 - 7.5e-25 87.6 21.1 2.6e-19 69.4 13.2 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GBG75492.1 - 5.7e-06 25.9 8.5 5.7e-06 25.9 8.5 2.1 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB HRG PF16954.5 GBG75492.1 - 0.0055 17.1 2.2 2.4 8.6 0.0 3.4 2 0 0 2 2 2 1 Haem-transporter, endosomal/lysosomal, haem-responsive gene Tub_N PF16322.5 GBG75492.1 - 0.12 12.7 3.2 0.27 11.6 3.2 1.5 1 0 0 1 1 1 0 Tubby N-terminal DUF3493 PF11998.8 GBG75492.1 - 9.4 6.5 8.2 12 6.2 0.1 3.5 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 IQ PF00612.27 GBG75493.1 - 2.2e-07 30.0 2.6 0.059 13.2 0.1 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Ribosomal_60s PF00428.19 GBG75493.1 - 5.5 7.7 25.3 0.19 12.3 16.5 3.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DDE_Tnp_4 PF13359.6 GBG75494.1 - 1.9e-28 99.1 0.0 2.7e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75494.1 - 9.5e-12 45.0 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG75494.1 - 0.03 14.0 0.2 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG75495.1 - 5.1e-06 26.8 0.2 7.1e-05 23.1 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG75495.1 - 0.0024 17.9 0.6 0.0076 16.3 0.6 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF531 PF04407.12 GBG75495.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF531) Retrotrans_gag PF03732.17 GBG75497.1 - 0.08 13.2 1.5 0.55 10.5 0.2 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein Filo_glycop PF01611.16 GBG75497.1 - 0.13 11.2 0.5 0.2 10.5 0.5 1.3 1 0 0 1 1 1 0 Filovirus glycoprotein Pkinase PF00069.25 GBG75498.1 - 6.2e-56 189.7 0.0 1.7e-53 181.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG75498.1 - 1.3e-37 129.5 0.0 5.5e-37 127.5 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG75498.1 - 0.00014 20.8 0.7 0.00035 19.5 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 GBG75498.1 - 0.018 14.4 0.2 0.064 12.6 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 GBG75498.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.27 GBG75499.1 - 1.3e-33 116.4 0.0 2.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG75499.1 - 8e-16 58.3 0.0 1.9e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG75499.1 - 3.8e-08 33.2 0.0 7.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75499.1 - 4.4e-05 23.3 0.0 8.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG75499.1 - 6.2e-05 23.6 0.0 0.00015 22.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75499.1 - 0.00042 20.8 0.0 0.0008 19.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG75499.1 - 0.084 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain zf-DBF PF07535.12 GBG75499.1 - 0.097 12.8 0.2 0.32 11.1 0.2 1.9 1 0 0 1 1 1 0 DBF zinc finger RT_RNaseH_2 PF17919.1 GBG75501.1 - 7e-22 77.4 0.0 4.8e-21 74.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75501.1 - 5.5e-20 71.6 0.0 1.2e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75501.1 - 4.5e-18 65.1 0.1 1.4e-17 63.5 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RapA_C PF12137.8 GBG75501.1 - 0.056 12.5 5.4 0.096 11.7 5.4 1.3 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal CLIP1_ZNF PF16641.5 GBG75501.1 - 3.4 7.6 7.6 1.3 9.0 2.7 2.3 2 0 0 2 2 2 0 CLIP1 zinc knuckle TFIIA PF03153.13 GBG75501.1 - 5.9 6.8 9.0 8.4 6.3 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TLC PF03219.14 GBG75503.1 - 2e-201 670.0 16.8 2.5e-201 669.7 16.8 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter Integrase_H2C2 PF17921.1 GBG75507.1 - 3.7e-14 52.6 0.1 6.6e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75507.1 - 0.0025 18.0 0.0 0.0068 16.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG75507.1 - 0.01 16.1 0.5 0.018 15.2 0.5 1.5 1 0 0 1 1 1 0 H2C2 zinc finger FRG PF08867.11 GBG75507.1 - 0.14 13.1 0.0 0.35 11.9 0.0 1.6 1 0 0 1 1 1 0 FRG domain AcylCoA_dehyd_C PF12186.8 GBG75507.1 - 0.36 11.0 1.3 0.74 10.0 1.3 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal RVT_1 PF00078.27 GBG75510.1 - 1.5e-28 99.9 0.1 2e-28 99.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75510.1 - 1.7e-09 37.6 0.0 3.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75510.1 - 0.00031 21.0 0.0 0.0006 20.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG75510.1 - 0.0064 16.3 0.1 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG75511.1 - 1.4e-08 34.4 2.0 3.1e-08 33.3 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF1943 PF09172.11 GBG75511.1 - 0.23 10.7 3.9 0.43 9.8 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Fzo_mitofusin PF04799.13 GBG75511.1 - 0.27 10.8 10.9 0.061 12.9 2.7 2.7 3 0 0 3 3 3 0 fzo-like conserved region RT_RNaseH_2 PF17919.1 GBG75512.1 - 1.1e-26 92.8 0.0 1.7e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75512.1 - 1.2e-23 83.4 0.0 2.2e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75512.1 - 4.7e-11 42.6 0.1 7.8e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ubiq-assoc PF09145.10 GBG75514.1 - 0.013 15.5 1.7 0.02 14.9 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-associated RVT_1 PF00078.27 GBG75516.1 - 1.4e-19 70.5 0.0 2.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75516.1 - 1.4e-14 53.9 1.4 4.2e-14 52.4 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG75516.1 - 5.6e-13 49.1 0.0 1.5e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG75516.1 - 3e-11 43.1 0.0 5.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG75516.1 - 0.00033 20.8 0.0 0.00075 19.7 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Chloroa_b-bind PF00504.21 GBG75520.1 - 4e-50 170.5 0.0 6.1e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF4746 PF15928.5 GBG75522.1 - 0.029 13.8 3.9 0.038 13.4 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 GBG75522.1 - 0.45 10.3 7.8 0.67 9.7 7.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GBG75522.1 - 2.3 6.4 12.3 3 6.0 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG75522.1 - 3.6 5.7 15.9 4.7 5.3 15.9 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG75522.1 - 6.6 5.4 6.0 8.9 5.0 6.0 1.1 1 0 0 1 1 1 0 Presenilin Chloroa_b-bind PF00504.21 GBG75523.1 - 4e-50 170.5 0.0 6.1e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 GBG75524.1 - 4e-50 170.5 0.0 6.1e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RT_RNaseH_2 PF17919.1 GBG75525.1 - 4.4e-24 84.4 0.2 1.1e-23 83.1 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75525.1 - 5e-16 59.0 0.2 6.1e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG75525.1 - 1.6e-11 44.4 0.0 4.4e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75525.1 - 5.5e-07 29.6 0.1 1.2e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG75525.1 - 0.00014 22.0 0.1 0.00039 20.6 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Chloroa_b-bind PF00504.21 GBG75527.1 - 2.7e-50 171.0 0.0 4.1e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Lipoxygenase PF00305.19 GBG75528.1 - 4.3e-120 402.2 0.0 1.8e-113 380.3 0.0 2.5 1 1 1 2 2 2 2 Lipoxygenase DUF2710 PF10921.8 GBG75529.1 - 0.062 13.7 0.2 7.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2710) Hexapep PF00132.24 GBG75530.1 - 1.2e-14 53.4 30.2 2.4e-05 23.9 2.0 5.9 3 2 1 5 5 5 5 Bacterial transferase hexapeptide (six repeats) DUF11 PF01345.18 GBG75530.1 - 0.014 15.7 0.3 0.04 14.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF11 RT_RNaseH PF17917.1 GBG75531.1 - 3.8e-23 81.8 0.0 9e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75531.1 - 5.1e-23 81.0 0.0 2.2e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75531.1 - 1.1e-19 70.9 1.2 1.5e-18 67.1 0.0 2.6 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75531.1 - 2.5e-19 69.1 0.1 5.3e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG75531.1 - 4e-08 33.1 0.0 8.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75531.1 - 1.3e-07 32.1 0.0 4.3e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75531.1 - 5.7e-06 26.8 0.1 2.2e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease LRR_8 PF13855.6 GBG75531.1 - 5.5e-05 22.8 0.0 0.00018 21.2 0.0 2.0 1 0 0 1 1 1 1 Leucine rich repeat Asp_protease PF09668.10 GBG75531.1 - 0.00058 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG75531.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG75532.1 - 3.1e-07 30.2 2.3 7.1e-07 29.0 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-Mss51 PF13824.6 GBG75532.1 - 0.058 13.5 0.3 0.058 13.5 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 GIY-YIG PF01541.24 GBG75533.1 - 6e-05 23.2 0.2 0.00055 20.1 0.0 2.5 2 0 0 2 2 2 1 GIY-YIG catalytic domain tRNA_anti-codon PF01336.25 GBG75533.1 - 0.31 11.0 3.0 13 5.9 0.2 3.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain RT_RNaseH_2 PF17919.1 GBG75534.1 - 1.7e-30 105.0 0.1 3.7e-30 103.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75534.1 - 6.7e-28 97.0 0.2 1.4e-27 96.1 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Malectin_like PF12819.7 GBG75534.1 - 9.4e-23 80.9 0.0 1.5e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Malectin-like domain RVT_1 PF00078.27 GBG75534.1 - 5.7e-21 75.1 3.2 4.9e-20 72.0 0.4 3.2 3 1 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75534.1 - 7.9e-19 67.5 0.1 1.6e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG75534.1 - 6.7e-07 29.1 0.0 3e-06 27.1 0.0 2.0 2 1 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG75534.1 - 1.1e-06 29.1 0.0 7.7e-05 23.2 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75534.1 - 1.6e-06 28.7 0.0 6.4e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG75534.1 - 4e-05 23.8 1.1 0.0048 17.2 0.7 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG75534.1 - 0.00073 19.7 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG75534.1 - 0.0014 18.8 0.0 0.004 17.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG75534.1 - 0.025 14.2 0.5 0.051 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Asp_protease PF09668.10 GBG75534.1 - 0.089 12.6 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 1 0 Aspartyl protease RVP PF00077.20 GBG75534.1 - 0.13 12.6 0.0 0.52 10.6 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease KfrA_N PF11740.8 GBG75535.1 - 0.13 12.9 17.3 2.4 8.9 9.6 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Syntaxin PF00804.25 GBG75535.1 - 0.29 10.8 3.8 0.58 9.8 0.2 2.6 3 0 0 3 3 3 0 Syntaxin DUF1664 PF07889.12 GBG75535.1 - 0.3 11.1 3.5 6.6 6.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Med3 PF11593.8 GBG75535.1 - 2.4 7.3 19.3 0.99 8.5 17.1 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.16 GBG75536.1 - 7.2e-33 114.0 30.6 2.9e-32 112.0 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GBG75536.1 - 1e-25 90.1 11.9 1.2e-17 63.5 4.2 4.0 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 GBG75536.1 - 9.7e-07 28.0 7.6 9.7e-07 28.0 7.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 GBG75536.1 - 4.2e-05 23.0 2.6 4.2e-05 23.0 2.6 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PTR2 PF00854.21 GBG75536.1 - 0.0086 15.0 3.8 0.017 13.9 2.3 2.2 2 0 0 2 2 2 1 POT family MFS_3 PF05977.13 GBG75536.1 - 0.66 8.3 8.5 0.013 13.9 0.6 1.9 2 1 0 2 2 2 0 Transmembrane secretion effector Pkinase_Tyr PF07714.17 GBG75537.1 - 2.7e-29 102.3 0.0 5e-29 101.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG75537.1 - 6.1e-29 101.2 0.0 9.3e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG75537.1 - 0.013 15.4 0.0 0.051 13.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family HCV_NS4a PF01006.20 GBG75537.1 - 2.1 8.2 9.7 1.4 8.7 1.0 3.3 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a DnaJ PF00226.31 GBG75538.1 - 5.6e-25 87.2 1.2 1.7e-24 85.7 1.2 1.9 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 GBG75538.1 - 4.4e-15 55.8 5.1 1.2e-14 54.4 5.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 GBG75538.1 - 0.00018 21.3 0.7 0.00072 19.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG75538.1 - 0.006 16.4 0.9 0.015 15.1 0.0 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3958 PF13125.6 GBG75538.1 - 0.015 15.5 1.7 0.039 14.1 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) TPR_6 PF13174.6 GBG75538.1 - 0.041 14.5 4.3 0.044 14.4 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG75538.1 - 0.17 12.2 0.5 0.61 10.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG75538.1 - 0.22 12.4 2.3 0.44 11.5 0.1 2.7 2 1 2 4 4 4 0 Tetratricopeptide repeat Sporozoite_P67 PF05642.11 GBG75538.1 - 2 6.4 7.5 3.7 5.5 7.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF702 PF05142.12 GBG75539.1 - 0.044 14.3 2.0 0.044 14.3 2.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF702) Hydrolase_4 PF12146.8 GBG75541.1 - 2.8e-09 36.6 0.0 4.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG75541.1 - 8.1e-07 28.9 0.2 2.2e-05 24.2 0.2 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3377 PF11857.8 GBG75541.1 - 0.22 11.4 0.7 0.64 10.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF4667 PF15700.5 GBG75541.1 - 0.56 10.3 14.7 2.9 7.9 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4667) DUF3446 PF11928.8 GBG75541.1 - 1.5 9.2 35.0 0.085 13.2 10.2 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain TPT PF03151.16 GBG75542.1 - 8.9e-51 172.9 21.8 1.2e-50 172.5 21.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG75542.1 - 3.3e-11 43.5 35.9 9.2e-06 25.9 17.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GBG75542.1 - 2.1e-09 37.0 21.5 3.5e-09 36.3 21.5 1.4 1 0 0 1 1 1 1 UAA transporter family Transgly_assoc PF04226.13 GBG75542.1 - 0.026 14.8 1.0 0.83 10.0 0.1 2.8 2 0 0 2 2 2 0 Transglycosylase associated protein SSP160 PF06933.11 GBG75542.1 - 0.1 10.8 8.1 0.18 10.0 8.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 GBG75542.1 - 9 4.1 4.9 12 3.7 4.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pec_lyase_C PF00544.19 GBG75543.1 - 3.4e-30 105.2 3.1 1.4e-29 103.2 3.1 1.9 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG75543.1 - 4.5e-06 26.6 0.7 9e-06 25.6 0.7 1.4 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG75543.1 - 0.0065 15.8 1.0 0.022 14.0 0.7 1.8 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Dzip-like_N PF13815.6 GBG75543.1 - 0.035 14.1 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Glyco_hydro_28 PF00295.17 GBG75544.1 - 3.4e-38 131.5 0.0 5.2e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 GBG75544.1 - 0.00041 20.3 0.5 0.14 12.0 0.0 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.6 GBG75544.1 - 0.012 15.5 5.7 0.027 14.3 5.7 1.6 1 0 0 1 1 1 0 Right handed beta helix region Malectin_like PF12819.7 GBG75545.1 - 2.3e-17 63.2 0.0 3.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Malectin-like domain Malectin PF11721.8 GBG75545.1 - 2.2e-11 44.1 0.0 0.0002 21.5 0.0 2.2 2 0 0 2 2 2 2 Malectin domain LRR_8 PF13855.6 GBG75545.1 - 1.6e-08 34.2 0.4 3.3e-08 33.2 0.4 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GBG75545.1 - 1.5e-05 25.2 2.0 6.3e-05 23.3 1.0 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG75545.1 - 0.028 14.9 3.5 0.15 12.7 0.6 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat RnaseA PF00074.20 GBG75546.1 - 0.029 14.8 0.3 0.036 14.5 0.3 1.3 1 0 0 1 1 1 0 Pancreatic ribonuclease Palm_thioest PF02089.15 GBG75547.1 - 0.2 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase POB3_N PF17292.2 GBG75548.1 - 4e-24 84.9 0.8 6.2e-23 81.1 0.0 2.7 3 0 0 3 3 3 1 POB3-like N-terminal PH domain HMG_box PF00505.19 GBG75548.1 - 2.2e-23 82.4 3.6 3.6e-23 81.8 3.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Rtt106 PF08512.12 GBG75548.1 - 2.6e-23 82.2 0.2 2.8e-22 78.9 0.1 2.4 2 1 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 GBG75548.1 - 1.7e-22 79.1 0.2 3.5e-22 78.1 0.2 1.6 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) HMG_box_2 PF09011.10 GBG75548.1 - 1.1e-17 64.4 3.9 2.2e-17 63.4 3.9 1.5 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 GBG75548.1 - 0.079 13.5 1.4 0.14 12.7 1.4 1.4 1 0 0 1 1 1 0 YABBY protein CDC45 PF02724.14 GBG75548.1 - 1.2 7.4 13.5 1.6 6.9 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG75548.1 - 4.5 7.3 21.8 7.4 6.6 21.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PNP_UDP_1 PF01048.20 GBG75549.1 - 5.8e-12 45.4 4.2 7.1e-09 35.3 4.6 2.7 2 1 0 2 2 2 2 Phosphorylase superfamily YL1 PF05764.13 GBG75549.1 - 7.1e-05 23.0 1.9 9.1e-05 22.7 1.9 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Sigma70_ner PF04546.13 GBG75549.1 - 0.0048 16.8 2.9 0.0096 15.8 2.9 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 GBG75549.1 - 0.039 13.7 9.8 0.059 13.1 9.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 GBG75549.1 - 0.048 14.1 14.7 0.1 13.0 14.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Utp14 PF04615.13 GBG75549.1 - 0.097 11.2 3.2 0.13 10.8 3.2 1.1 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.14 GBG75549.1 - 0.12 10.7 2.9 0.17 10.2 2.9 1.2 1 0 0 1 1 1 0 CDC45-like protein EMC3_TMCO1 PF01956.16 GBG75549.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PGA2 PF07543.12 GBG75549.1 - 0.37 10.8 3.7 0.91 9.5 3.7 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 RRN3 PF05327.11 GBG75549.1 - 0.92 8.0 5.5 1.3 7.5 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 GBG75549.1 - 1.3 8.6 4.4 3.1 7.3 4.4 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 GBG75549.1 - 1.7 6.8 6.9 2.3 6.3 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG75549.1 - 2.1 6.3 12.9 3.1 5.8 12.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GBG75549.1 - 3 7.1 15.7 4.7 6.4 15.7 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 GBG75549.1 - 4.7 6.2 18.3 8.4 5.4 18.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.6 GBG75549.1 - 7.9 6.9 17.0 18 5.8 17.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_41 PF13844.6 GBG75551.1 - 0.021 13.3 0.9 0.035 12.5 0.9 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 41 CDC45 PF02724.14 GBG75551.1 - 0.48 8.6 8.7 0.56 8.4 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 GBG75551.1 - 2.1 8.4 14.2 0.26 11.4 9.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 GBG75551.1 - 2.9 6.6 7.3 0.66 8.7 4.0 1.6 2 0 0 2 2 2 0 Presenilin MMR_HSR1 PF01926.23 GBG75552.1 - 9.3e-20 70.8 0.0 2.3e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 GBG75552.1 - 1.3e-19 70.3 3.0 1.3e-18 67.1 3.0 2.6 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 GBG75552.1 - 3.4e-06 26.7 0.0 0.00019 21.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 GBG75552.1 - 0.0012 18.7 0.0 0.17 11.6 0.1 2.7 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Arf PF00025.21 GBG75552.1 - 0.0039 16.7 0.0 5.6 6.4 0.1 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family MeaB PF03308.16 GBG75552.1 - 0.0045 16.0 0.4 0.53 9.2 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Sde2_N_Ubi PF13019.6 GBG75552.1 - 0.0082 16.0 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain GTP_EFTU PF00009.27 GBG75552.1 - 0.048 13.2 0.2 0.8 9.2 0.3 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Ribosomal_L31e PF01198.19 GBG75553.1 - 2.3e-42 143.1 3.7 2.9e-42 142.8 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e RPAP2_Rtr1 PF04181.13 GBG75554.1 - 5.9e-14 52.1 0.7 1.3e-13 51.0 0.7 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Retrotrans_gag PF03732.17 GBG75555.1 - 0.00056 20.1 0.0 0.0021 18.3 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG75555.1 - 0.026 14.3 0.5 0.078 12.8 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DHquinase_I PF01487.15 GBG75557.1 - 7.9e-64 216.0 0.0 1.1e-63 215.6 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 GBG75557.1 - 1.3e-21 76.6 0.0 2.9e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 GBG75557.1 - 5.4e-05 22.9 1.2 7.9e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 GBG75557.1 - 0.00071 19.6 0.1 0.0018 18.3 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 GBG75557.1 - 0.0035 17.9 1.2 0.0096 16.5 0.3 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 GBG75557.1 - 0.0058 15.8 1.5 0.01 15.0 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain AdoHcyase_NAD PF00670.21 GBG75557.1 - 0.0072 16.4 0.5 0.014 15.5 0.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short PF00106.25 GBG75557.1 - 0.029 13.8 0.6 0.057 12.9 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase IlvN PF07991.12 GBG75557.1 - 0.05 13.2 0.2 0.097 12.2 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GPI2 PF06432.11 GBG75557.1 - 0.25 10.8 0.5 0.38 10.2 0.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase RVT_1 PF00078.27 GBG75558.1 - 4e-09 36.3 0.0 7.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SURF2 PF05477.11 GBG75560.1 - 0.16 11.6 1.0 0.84 9.3 1.0 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) DUF4746 PF15928.5 GBG75561.1 - 2 7.8 7.7 3.2 7.1 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RVT_1 PF00078.27 GBG75565.1 - 1e-28 100.4 0.1 1.6e-28 99.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75565.1 - 1.5e-16 60.2 1.1 4.1e-16 58.8 1.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75565.1 - 2.2e-07 31.1 0.0 5.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG75565.1 - 3e-05 24.2 0.3 7.6e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75565.1 - 0.0005 20.1 0.1 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG75565.1 - 0.0015 18.4 0.3 0.023 14.6 0.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG75565.1 - 0.0017 18.5 0.2 0.0051 17.0 0.2 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 GBG75565.1 - 0.0069 16.2 0.0 0.3 10.8 0.0 2.3 1 1 1 2 2 2 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG75566.1 - 1.8e-08 34.6 0.0 3.6e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG75566.1 - 2.4 6.4 6.8 2.7 6.2 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-bind_4 PF13837.6 GBG75567.1 - 5.2e-07 30.0 0.3 1.4e-06 28.6 0.3 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF3961 PF13106.6 GBG75567.1 - 1.9 8.2 3.2 35 4.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) DDE_Tnp_4 PF13359.6 GBG75568.1 - 4.6e-27 94.6 0.0 8.1e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75568.1 - 1.5e-16 60.6 0.0 2.3e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG75568.1 - 0.12 12.0 0.0 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain Fasciclin PF02469.22 GBG75569.1 - 1.3e-16 60.9 0.0 1.9e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 GBG75570.1 - 2e-15 57.1 0.0 2.8e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain DUF659 PF04937.15 GBG75572.1 - 2.2e-21 76.3 0.0 3.7e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Fasciclin PF02469.22 GBG75572.1 - 3.1e-14 53.3 0.0 6.3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain Dimer_Tnp_hAT PF05699.14 GBG75572.1 - 0.0016 18.2 0.2 0.0036 17.0 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Myb_DNA-bind_5 PF13873.6 GBG75573.1 - 0.05 13.7 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain NOA36 PF06524.12 GBG75573.1 - 0.24 10.7 19.1 0.42 9.9 19.1 1.4 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 GBG75573.1 - 0.64 9.3 12.1 1 8.6 12.1 1.2 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 GBG75573.1 - 1.2 9.1 15.3 0.26 11.3 10.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GCIP PF13324.6 GBG75573.1 - 9.6 5.7 7.3 15 5.1 7.3 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting V_ATPase_I PF01496.19 GBG75574.1 - 0.013 13.4 0.7 0.016 13.1 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NinG PF05766.12 GBG75574.1 - 0.063 13.2 8.7 0.11 12.4 8.7 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein ORC3_N PF07034.11 GBG75574.1 - 0.32 10.0 2.7 0.52 9.4 2.7 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Jak1_Phl PF17887.1 GBG75574.1 - 0.59 10.1 4.8 1.2 9.0 4.8 1.5 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Cnd1_N PF12922.7 GBG75574.1 - 1.2 9.0 6.7 2.1 8.1 6.7 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term MscS_TM PF12794.7 GBG75574.1 - 2.3 7.0 4.1 3.3 6.5 4.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF3464 PF11947.8 GBG75574.1 - 3.3 7.5 7.6 5.5 6.7 7.6 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TAF4 PF05236.14 GBG75574.1 - 6 6.5 16.2 11 5.6 16.2 1.5 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BTB PF00651.31 GBG75575.1 - 3.9e-10 39.9 0.0 1.6e-09 38.0 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain SDA1 PF05285.12 GBG75575.1 - 7.1 5.9 8.5 10 5.4 8.5 1.3 1 0 0 1 1 1 0 SDA1 Fasciclin PF02469.22 GBG75576.1 - 2.4e-13 50.4 0.0 3.2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain TFIIF_alpha PF05793.12 GBG75579.1 - 0.29 9.7 22.0 0.42 9.1 22.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2526 PF10735.9 GBG75579.1 - 0.34 11.1 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) Nop53 PF07767.11 GBG75579.1 - 0.39 10.0 18.6 0.53 9.6 18.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GBG75579.1 - 2.1 6.5 18.6 2.7 6.1 18.6 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 GBG75579.1 - 5.5 7.3 10.1 9 6.6 10.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 GBG75579.1 - 6.9 6.0 20.2 9.9 5.5 20.2 1.2 1 0 0 1 1 1 0 SDA1 DDE_Tnp_4 PF13359.6 GBG75580.1 - 7.1e-24 84.3 0.0 9.9e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75580.1 - 1.4e-10 41.1 0.0 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG75580.1 - 0.0092 15.6 1.7 3.4 7.2 0.0 2.7 2 1 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG75581.1 - 1.2e-07 32.0 0.9 2.4e-07 31.0 0.9 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG75581.1 - 0.01 16.0 0.7 0.035 14.3 0.7 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG75581.1 - 0.023 14.9 0.2 0.049 13.9 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG75581.1 - 0.048 14.0 0.5 0.11 12.9 0.5 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CDC45 PF02724.14 GBG75584.1 - 1 7.5 14.1 1.7 6.8 14.1 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG75584.1 - 5.4 6.4 25.4 7.4 5.9 25.4 1.1 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.7 GBG75584.1 - 9.9 4.1 7.5 13 3.7 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDE_Tnp_4 PF13359.6 GBG75585.1 - 1.1e-24 86.9 0.0 1.6e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75585.1 - 3.9e-10 39.7 0.0 6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG75585.1 - 0.00012 21.8 1.2 0.0043 16.7 1.2 2.5 1 1 0 1 1 1 1 Transposase DDE domain pP_pnuc_1 PF18165.1 GBG75585.1 - 0.04 13.8 0.3 7.2 6.5 0.1 2.3 1 1 1 2 2 2 0 Predicted pPIWI-associating nuclease SHD1 PF03983.12 GBG75585.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 Myb_DNA-bind_4 PF13837.6 GBG75586.1 - 8e-07 29.3 0.5 1.9e-06 28.1 0.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Senescence PF06911.12 GBG75586.1 - 0.007 16.7 0.5 0.017 15.4 0.1 1.7 2 0 0 2 2 2 1 Senescence-associated protein Myb_DNA-binding PF00249.31 GBG75586.1 - 0.018 15.3 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG75586.1 - 0.038 14.2 0.1 0.079 13.2 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG75586.1 - 0.04 14.2 0.3 0.079 13.3 0.3 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-3CxxC PF13695.6 GBG75586.1 - 0.26 11.8 1.7 0.51 10.8 1.7 1.4 1 0 0 1 1 1 0 Zinc-binding domain DUF659 PF04937.15 GBG75587.1 - 9.8e-17 61.2 0.0 1.5e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG75587.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Nop14 PF04147.12 GBG75588.1 - 0.98 7.5 10.5 1.2 7.2 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family ATE_N PF04376.13 GBG75589.1 - 0.046 14.1 0.2 0.71 10.3 0.0 2.5 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus RT_RNaseH_2 PF17919.1 GBG75590.1 - 4.1e-21 74.9 0.0 8.5e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75590.1 - 1.6e-19 70.2 0.0 3.8e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75590.1 - 6.4e-13 48.6 0.3 1.5e-12 47.4 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Jnk-SapK_ap_N PF09744.9 GBG75590.1 - 0.0059 16.8 0.7 0.0059 16.8 0.7 2.1 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 zf-H2C2 PF09337.10 GBG75590.1 - 0.087 13.1 0.5 0.19 12.0 0.5 1.6 1 0 0 1 1 1 0 H2C2 zinc finger TEX19 PF15553.6 GBG75590.1 - 0.092 12.7 0.5 1.7 8.6 0.6 2.7 2 0 0 2 2 2 0 Testis-expressed protein 19 TPR_MLP1_2 PF07926.12 GBG75590.1 - 0.79 9.8 7.9 0.37 10.9 5.1 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RVT_1 PF00078.27 GBG75592.1 - 4.9e-24 85.1 0.2 7.2e-24 84.5 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG75592.1 - 3.9e-19 69.0 0.0 4e-18 65.6 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG75592.1 - 1.6e-16 60.5 0.0 6.2e-16 58.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain GRA6 PF05084.13 GBG75592.1 - 0.0043 17.0 0.2 0.029 14.3 0.1 2.0 2 0 0 2 2 2 1 Granule antigen protein (GRA6) DUF659 PF04937.15 GBG75593.1 - 1.3e-34 119.3 0.0 2.1e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG75593.1 - 3.4e-07 29.9 0.1 3.2e-06 26.8 0.1 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DNA_pol_phi PF04931.13 GBG75593.1 - 9.6 4.2 7.2 15 3.6 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi RT_RNaseH_2 PF17919.1 GBG75594.1 - 1.5e-30 105.2 0.0 3.3e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75594.1 - 1.7e-18 66.9 0.2 4.2e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75594.1 - 2.3e-18 66.4 0.0 6.3e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75594.1 - 2.6e-10 40.5 0.0 5.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG75594.1 - 0.00092 19.3 0.2 0.0021 18.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG75594.1 - 0.0027 18.0 0.0 0.01 16.1 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein Pkinase_Tyr PF07714.17 GBG75595.1 - 3e-76 256.1 0.0 7.9e-37 126.9 0.0 2.7 2 2 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG75595.1 - 2.7e-69 233.5 0.0 2.3e-33 115.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG75595.1 - 5.1e-23 81.0 0.0 1.2e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75595.1 - 2.9e-20 72.5 0.0 9.1e-20 70.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75595.1 - 6e-16 58.6 0.0 2.7e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG75595.1 - 2.8e-05 24.7 0.0 0.00019 22.0 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG75595.1 - 7.7e-05 22.4 1.4 0.00021 21.0 0.0 2.5 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG75595.1 - 0.00031 21.3 0.0 0.0014 19.1 0.0 2.3 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG75595.1 - 0.001 19.3 9.9 0.015 15.6 0.0 4.2 5 0 0 5 5 4 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG75595.1 - 0.0063 16.3 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75595.1 - 0.0093 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease M PF02370.16 GBG75595.1 - 0.17 12.5 8.3 1.3 9.8 0.5 3.0 2 0 0 2 2 2 0 M protein repeat CDC45 PF02724.14 GBG75595.1 - 4 5.6 31.0 9.2 4.4 31.0 1.6 1 0 0 1 1 1 0 CDC45-like protein DUF812 PF05667.11 GBG75597.1 - 0.1 11.4 2.1 0.14 11.0 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DDE_Tnp_4 PF13359.6 GBG75598.1 - 5.2e-28 97.7 0.0 9.8e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75598.1 - 4.9e-15 55.7 0.1 1.6e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG75598.1 - 0.014 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG75598.1 - 0.18 11.4 0.6 6.6 6.3 0.4 2.3 1 1 1 2 2 2 0 Transposase DDE domain Pkinase PF00069.25 GBG75599.1 - 1.4e-25 90.2 0.0 2.5e-16 59.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG75599.1 - 3.3e-24 85.6 0.0 5.1e-13 48.9 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase PQQ_3 PF13570.6 GBG75599.1 - 0.13 12.8 1.0 0.61 10.7 0.2 2.5 2 0 0 2 2 2 0 PQQ-like domain DUF4366 PF14283.6 GBG75600.1 - 0.19 11.7 2.4 0.33 11.0 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SpoIIP PF07454.11 GBG75600.1 - 0.31 10.5 4.3 0.41 10.1 4.3 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EIF4E-T PF10477.9 GBG75600.1 - 0.36 9.6 12.9 0.52 9.1 12.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Presenilin PF01080.17 GBG75600.1 - 0.95 8.2 5.5 1.3 7.8 5.5 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG75600.1 - 3.5 5.8 14.0 4.7 5.4 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 GBG75600.1 - 6.1 6.9 14.6 9.2 6.3 14.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 BTB PF00651.31 GBG75601.1 - 4.9e-16 59.0 0.0 2.7e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 GBG75602.1 - 8.1e-12 45.4 0.0 1.6e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GBG75605.1 - 5.2e-15 55.6 0.0 1.1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 GBG75605.1 - 0.051 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF1127 PF06568.11 GBG75606.1 - 1.9 8.3 3.8 14 5.5 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) gag-asp_proteas PF13975.6 GBG75608.1 - 6.2e-07 29.9 0.3 1.4e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75608.1 - 8.4e-05 23.1 0.0 0.00019 22.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG75608.1 - 0.005 16.6 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG75608.1 - 0.02 14.6 0.3 0.046 13.4 0.3 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG75608.1 - 0.048 13.4 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG75608.1 - 0.12 12.6 0.6 0.21 11.7 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle BTB PF00651.31 GBG75614.1 - 4e-16 59.2 0.0 8.2e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Caldesmon PF02029.15 GBG75614.1 - 7.7e-05 21.6 11.0 9.7e-05 21.3 11.0 1.1 1 0 0 1 1 1 1 Caldesmon Skp1_POZ PF03931.15 GBG75614.1 - 0.00057 20.0 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 1 1 Skp1 family, tetramerisation domain SPRY PF00622.28 GBG75614.1 - 0.0036 17.4 0.0 0.04 14.0 0.0 2.3 1 1 0 1 1 1 1 SPRY domain RRN3 PF05327.11 GBG75614.1 - 0.029 12.9 8.9 0.042 12.4 8.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MDM1 PF15501.6 GBG75614.1 - 0.029 13.5 9.3 0.039 13.1 9.3 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 SpoIIP PF07454.11 GBG75614.1 - 0.032 13.7 6.3 0.046 13.2 6.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 GBG75614.1 - 0.049 13.8 0.2 0.063 13.4 0.2 1.3 1 0 0 1 1 1 0 DDHD domain SpoIIIAH PF12685.7 GBG75614.1 - 0.068 13.0 8.6 0.11 12.3 8.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein BUD22 PF09073.10 GBG75614.1 - 0.084 12.2 15.1 0.12 11.7 15.1 1.1 1 0 0 1 1 1 0 BUD22 SCAI PF12070.8 GBG75614.1 - 0.13 11.1 0.9 0.18 10.6 0.9 1.1 1 0 0 1 1 1 0 Protein SCAI SDA1 PF05285.12 GBG75614.1 - 0.21 11.0 19.6 0.3 10.5 19.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG75614.1 - 0.26 9.5 14.5 0.35 9.1 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5523 PF17661.1 GBG75614.1 - 0.39 10.4 20.6 0.61 9.7 20.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) NARP1 PF12569.8 GBG75614.1 - 0.41 9.5 9.3 0.58 9.0 9.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF913 PF06025.12 GBG75614.1 - 0.6 9.0 5.7 0.98 8.3 5.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3408 PF11888.8 GBG75614.1 - 0.71 10.0 14.4 1.3 9.1 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) PPL5 PF18168.1 GBG75614.1 - 0.82 8.9 5.9 1.2 8.3 5.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 CobT PF06213.12 GBG75614.1 - 0.95 8.8 22.3 1.4 8.2 22.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sec62 PF03839.16 GBG75614.1 - 0.97 8.9 6.8 1.4 8.4 6.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Nop14 PF04147.12 GBG75614.1 - 1.3 7.2 21.4 1.7 6.7 21.4 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG75614.1 - 1.4 7.3 23.8 2 6.8 23.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Connexin PF00029.19 GBG75614.1 - 1.5 8.5 8.8 2.5 7.8 8.8 1.3 1 0 0 1 1 1 0 Connexin SAPS PF04499.15 GBG75614.1 - 1.7 7.3 7.6 2.3 6.9 7.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GBG75614.1 - 2.5 6.8 9.0 3.5 6.3 9.0 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 GBG75614.1 - 2.8 8.1 11.2 4.6 7.4 11.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ORC_WH_C PF18137.1 GBG75614.1 - 3.1 7.9 14.5 5.2 7.1 14.5 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF4628 PF15429.6 GBG75614.1 - 3.7 7.1 9.4 6.1 6.4 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) NPR3 PF03666.13 GBG75614.1 - 5.2 5.7 9.6 7.9 5.1 9.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PTPRCAP PF15713.5 GBG75614.1 - 6.2 7.1 23.6 13 6.0 23.6 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated XAP5 PF04921.14 GBG75614.1 - 6.5 6.5 13.2 10 5.9 13.2 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator TRAP_alpha PF03896.16 GBG75614.1 - 7.4 5.7 12.5 11 5.1 12.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop53 PF07767.11 GBG75614.1 - 8.7 5.6 23.3 13 5.1 23.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF719 PF05334.13 GBG75615.1 - 0.83 9.8 5.7 0.47 10.6 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF719) SDA1 PF05285.12 GBG75618.1 - 0.0051 16.3 27.8 0.0061 16.0 27.8 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG75618.1 - 0.44 8.8 25.1 0.56 8.4 25.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Asp-B-Hydro_N PF05279.11 GBG75618.1 - 0.8 9.7 32.5 1 9.4 32.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region YL1 PF05764.13 GBG75618.1 - 1 9.4 34.7 1.7 8.7 34.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GBG75618.1 - 2.2 6.4 36.7 2.9 6.0 36.7 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 GBG75618.1 - 2.6 6.1 12.0 2.6 6.1 12.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.15 GBG75618.1 - 3.1 7.3 17.7 4 6.9 17.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S64 PF08192.11 GBG75618.1 - 9.3 4.6 5.4 11 4.4 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 BTB PF00651.31 GBG75619.1 - 7.2e-13 48.7 0.0 2.1e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Wzy_C PF04932.15 GBG75620.1 - 0.00065 19.4 0.0 0.001 18.7 0.0 1.3 1 1 0 1 1 1 1 O-Antigen ligase GPI2 PF06432.11 GBG75620.1 - 0.0011 18.5 2.8 0.0012 18.3 2.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Pex24p PF06398.11 GBG75620.1 - 0.017 14.1 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin TraG_N PF07916.11 GBG75620.1 - 0.22 10.3 7.7 0.25 10.1 7.7 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Halogen_Hydrol PF10112.9 GBG75620.1 - 0.26 11.3 1.8 0.39 10.7 1.8 1.3 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4870 PF09685.10 GBG75620.1 - 1.2 9.3 12.6 1.9 8.6 12.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) EphA2_TM PF14575.6 GBG75620.1 - 2.2 9.2 21.3 1.8e+04 -3.5 21.3 2.9 1 1 0 1 1 0 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 GBG75620.1 - 2.5 6.8 9.0 3.2 6.4 9.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CDC45 PF02724.14 GBG75620.1 - 3.3 5.9 7.3 4 5.6 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Amastin PF07344.11 GBG75620.1 - 5.4 6.9 18.6 6.5 6.6 18.6 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein SDA1 PF05285.12 GBG75620.1 - 7.8 5.8 14.0 9.6 5.5 14.0 1.1 1 0 0 1 1 1 0 SDA1 GRP PF07172.11 GBG75620.1 - 9.4 7.0 20.4 65 4.3 20.0 2.3 1 1 0 1 1 1 0 Glycine rich protein family Homeodomain PF00046.29 GBG75621.1 - 9.2e-14 51.0 0.1 1.5e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GBG75621.1 - 0.0001 22.1 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 GBG75621.1 - 0.067 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) Homez PF11569.8 GBG75621.1 - 0.073 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeodomain PF00046.29 GBG75622.1 - 4.9e-14 51.9 1.5 8.2e-14 51.2 1.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GBG75622.1 - 3.3e-06 26.9 0.1 7.5e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 GBG75622.1 - 0.031 13.8 0.1 0.078 12.5 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Topo_Zn_Ribbon PF08272.11 GBG75624.1 - 0.067 12.9 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease_2 PF13650.6 GBG75624.1 - 0.13 12.9 0.1 0.28 11.9 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG75624.1 - 0.5 10.5 2.5 1.1 9.4 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle NPV_P10 PF05531.12 GBG75625.1 - 0.0047 17.3 6.1 1.9 9.0 0.1 5.2 4 1 0 4 4 4 2 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 GBG75625.1 - 0.0097 16.1 4.6 0.0097 16.1 4.6 5.0 3 2 2 5 5 5 3 Fibrinogen alpha/beta chain family Peptidase_U32_C PF16325.5 GBG75625.1 - 0.58 10.5 3.6 0.48 10.7 0.2 2.6 3 0 0 3 3 3 0 Peptidase family U32 C-terminal domain zf-FCS PF06467.14 GBG75626.1 - 0.11 12.5 0.7 0.19 11.7 0.7 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif TT_ORF2 PF02957.15 GBG75626.1 - 0.24 12.3 4.1 0.12 13.3 2.2 1.6 1 1 0 1 1 1 0 TT viral ORF2 RVT_1 PF00078.27 GBG75628.1 - 1.8e-36 125.8 0.0 3.6e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75628.1 - 2.6e-29 101.2 0.0 8.4e-29 99.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75628.1 - 7.5e-24 84.0 0.0 2e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sugar_tr PF00083.24 GBG75628.1 - 3.1e-15 56.0 20.7 3.1e-15 56.0 20.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 GBG75628.1 - 3.5e-07 29.5 23.6 7.3e-07 28.4 23.6 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Angiomotin_C PF12240.8 GBG75630.1 - 0.015 14.9 1.4 0.015 14.9 1.4 2.1 2 0 0 2 2 2 0 Angiomotin C terminal FapA PF03961.13 GBG75630.1 - 0.26 9.8 2.2 0.47 9.0 2.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 GBG75630.1 - 0.3 11.1 1.2 3.5 7.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 GBG75630.1 - 0.35 11.4 2.8 0.15 12.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 GBG75630.1 - 3.3 8.4 5.8 6 7.6 2.6 2.8 2 1 1 3 3 3 0 SlyX Nefa_Nip30_N PF10187.9 GBG75630.1 - 4.5 7.7 6.6 0.61 10.5 0.3 2.3 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Macoilin PF09726.9 GBG75630.1 - 5.4 5.5 13.2 0.049 12.2 3.0 2.0 2 0 0 2 2 2 0 Macoilin family Angiomotin_C PF12240.8 GBG75631.1 - 0.015 14.9 1.4 0.015 14.9 1.4 2.2 2 0 0 2 2 2 0 Angiomotin C terminal FapA PF03961.13 GBG75631.1 - 0.26 9.8 2.2 0.46 9.0 2.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 GBG75631.1 - 0.28 11.2 1.2 3.4 7.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 GBG75631.1 - 0.35 11.4 2.8 0.15 12.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF641 PF04859.12 GBG75631.1 - 1.5 9.2 5.6 5.2 7.4 1.0 2.7 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 GBG75631.1 - 3 8.5 5.8 5.9 7.6 2.6 2.8 2 1 1 3 3 3 0 SlyX Nefa_Nip30_N PF10187.9 GBG75631.1 - 4 7.9 6.3 0.6 10.5 0.3 2.3 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Macoilin PF09726.9 GBG75631.1 - 6.2 5.2 13.1 0.048 12.2 3.0 1.9 2 0 0 2 2 2 0 Macoilin family Asp_protease_2 PF13650.6 GBG75632.1 - 0.0019 18.8 0.0 0.0034 18.0 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG75633.1 - 0.0047 17.0 5.0 0.015 15.3 5.0 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG75633.1 - 0.021 14.7 5.2 0.056 13.3 5.2 1.8 1 0 0 1 1 1 0 Zinc knuckle GIY-YIG PF01541.24 GBG75633.1 - 0.051 13.8 0.1 0.37 11.1 0.0 2.5 2 0 0 2 2 2 0 GIY-YIG catalytic domain RVT_1 PF00078.27 GBG75635.1 - 1.5e-25 90.0 0.1 2.3e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75635.1 - 7e-18 64.9 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75635.1 - 7.3e-15 54.8 0.0 1.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ABC_tran PF00005.27 GBG75636.1 - 2.7e-52 176.9 6.1 1.5e-25 90.3 0.1 3.6 4 0 0 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 GBG75636.1 - 2.3e-20 72.4 22.6 2e-18 66.2 0.5 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GBG75636.1 - 4.3e-13 49.7 1.4 0.0012 18.7 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GBG75636.1 - 4.6e-08 32.8 3.7 0.027 13.9 0.0 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GBG75636.1 - 1.6e-06 27.7 0.6 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG75636.1 - 6.9e-05 23.1 1.1 0.08 13.2 0.0 3.5 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GBG75636.1 - 7e-05 22.6 3.6 0.15 11.8 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 GBG75636.1 - 8.9e-05 22.7 0.0 0.09 12.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 GBG75636.1 - 9.6e-05 22.8 0.3 0.089 13.2 0.1 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 GBG75636.1 - 0.00015 21.8 0.0 0.051 13.7 0.0 2.9 2 1 1 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GBG75636.1 - 0.00018 21.9 2.2 0.48 10.8 0.0 3.1 4 0 0 4 4 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GBG75636.1 - 0.001 19.0 0.6 0.23 11.4 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 GBG75636.1 - 0.0029 17.7 0.5 0.3 11.2 0.0 3.1 3 0 0 3 3 3 1 Dynamin family MeaB PF03308.16 GBG75636.1 - 0.0037 16.3 0.2 0.075 12.0 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 GBG75636.1 - 0.0039 17.7 2.8 1.2 9.7 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 GBG75636.1 - 0.0085 15.8 0.0 4.3 7.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GBG75636.1 - 0.012 15.1 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 GBG75636.1 - 0.017 15.6 17.9 0.061 13.8 0.0 4.8 5 0 0 5 5 5 0 AAA domain AAA_28 PF13521.6 GBG75636.1 - 0.019 15.2 0.0 0.57 10.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GBG75636.1 - 0.019 14.5 0.0 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 GBG75636.1 - 0.039 13.6 0.9 2.9 7.5 0.1 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 GBG75636.1 - 0.055 13.9 4.1 4.2 7.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 GBG75636.1 - 0.058 12.8 0.3 2.3 7.6 0.0 2.9 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 GBG75636.1 - 0.064 13.2 1.0 2.9 7.8 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.6 GBG75636.1 - 0.11 12.1 0.4 2.3 7.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 GBG75636.1 - 0.13 11.9 4.7 2.1 8.0 0.0 3.8 4 0 0 4 4 4 0 Thymidylate kinase AAA_5 PF07728.14 GBG75636.1 - 0.2 11.6 0.7 18 5.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 GBG75636.1 - 0.32 10.7 13.5 3.8 7.1 7.0 3.6 2 2 0 2 2 2 0 AAA ATPase domain TPM_phosphatase PF04536.14 GBG75637.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 TPM domain APC1_C PF18122.1 GBG75638.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain TPR_20 PF14561.6 GBG75638.1 - 0.12 12.7 0.7 0.24 11.8 0.3 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2358 PF10184.9 GBG75639.1 - 2.3e-36 124.5 0.1 3.4e-36 123.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Sporozoite_P67 PF05642.11 GBG75639.1 - 8e-07 27.6 8.5 3e-06 25.6 0.3 2.4 2 1 0 2 2 2 2 Sporozoite P67 surface antigen RNase_H2_suC PF08615.11 GBG75639.1 - 0.0028 17.8 1.1 0.39 10.9 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SnoaL_2 PF12680.7 GBG75639.1 - 0.0035 17.9 0.6 0.013 16.1 0.2 2.1 2 0 0 2 2 2 1 SnoaL-like domain DUF2052 PF09747.9 GBG75639.1 - 0.0096 16.1 17.4 0.45 10.6 1.9 2.3 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Na_trans_assoc PF06512.13 GBG75639.1 - 0.015 15.6 8.7 0.46 10.7 0.4 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated MMU163 PF17119.5 GBG75639.1 - 0.016 14.4 3.0 3.2 6.8 0.0 4.2 4 0 0 4 4 4 0 Mitochondrial protein up-regulated during meiosis FAM176 PF14851.6 GBG75639.1 - 0.042 13.5 15.2 0.59 9.8 6.2 2.3 2 0 0 2 2 2 0 FAM176 family SAPS PF04499.15 GBG75639.1 - 0.053 12.3 0.5 0.077 11.8 0.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CENP-B_dimeris PF09026.10 GBG75639.1 - 0.059 13.8 13.2 0.38 11.2 4.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3438 PF11920.8 GBG75639.1 - 0.07 12.4 0.2 0.07 12.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3438) Mlh1_C PF16413.5 GBG75639.1 - 0.1 11.9 4.3 0.4 10.0 1.3 2.1 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus Radial_spoke PF04712.12 GBG75639.1 - 0.11 11.4 23.4 0.25 10.2 10.2 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein CPSF100_C PF13299.6 GBG75639.1 - 0.13 12.4 6.7 2.7 8.1 2.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIIAH PF12685.7 GBG75639.1 - 0.14 11.9 8.7 1.7 8.4 0.6 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein BUD22 PF09073.10 GBG75639.1 - 0.22 10.8 17.7 0.73 9.1 3.2 2.4 2 0 0 2 2 2 0 BUD22 CBF PF03914.17 GBG75639.1 - 0.44 10.6 3.6 11 6.0 0.2 2.3 2 0 0 2 2 2 0 CBF/Mak21 family DUF4637 PF15470.6 GBG75639.1 - 0.49 10.1 25.7 0.22 11.2 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) RPA43_OB PF17875.1 GBG75639.1 - 0.64 10.6 7.0 13 6.5 2.4 2.8 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Prothymosin PF03247.14 GBG75639.1 - 0.76 10.3 35.6 0.62 10.5 15.7 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family MPP6 PF10175.9 GBG75639.1 - 0.84 10.1 14.6 2.8 8.4 1.0 2.5 2 0 0 2 2 2 0 M-phase phosphoprotein 6 MAT1 PF06391.13 GBG75639.1 - 0.92 9.3 13.5 0.39 10.5 6.2 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 GEN1_C PF18380.1 GBG75639.1 - 1.2 10.1 10.1 11 6.9 3.8 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Tim54 PF11711.8 GBG75639.1 - 1.4 7.6 11.3 0.58 8.9 2.7 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 GBG75639.1 - 1.6 7.4 7.7 2.6 6.7 7.7 1.3 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 GBG75639.1 - 1.7 8.0 0.0 1.7 8.0 0.0 3.0 2 1 0 2 2 1 0 SDA1 Serinc PF03348.15 GBG75639.1 - 1.8 7.4 4.1 8.5 5.2 0.0 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) Sigma70_ner PF04546.13 GBG75639.1 - 2 8.3 16.5 2.7 7.8 1.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Mak16 PF04874.14 GBG75639.1 - 2.2 8.9 27.8 5.8 7.6 12.0 2.4 2 0 0 2 2 2 0 Mak16 protein C-terminal region NOA36 PF06524.12 GBG75639.1 - 3.5 6.9 17.0 1.5 8.1 6.9 2.2 2 0 0 2 2 2 0 NOA36 protein Connexin PF00029.19 GBG75639.1 - 3.6 7.3 10.2 2.6 7.7 4.4 2.2 2 0 0 2 2 2 0 Connexin SpoIIP PF07454.11 GBG75639.1 - 3.7 6.9 9.3 5 6.5 3.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) THOC2_N PF16134.5 GBG75639.1 - 7 5.1 9.1 0.29 9.7 2.1 1.9 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus DAP PF15228.6 GBG75639.1 - 7.6 7.8 9.5 10 7.4 0.4 2.7 2 0 0 2 2 2 0 Death-associated protein Nop14 PF04147.12 GBG75639.1 - 8.1 4.5 21.9 0.43 8.7 7.2 2.1 2 0 0 2 2 2 0 Nop14-like family RR_TM4-6 PF06459.12 GBG75639.1 - 9.9 5.9 15.2 1.8 8.3 4.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 GBG75640.1 - 3.8e-35 119.5 1.4 2.6e-17 62.4 0.4 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG75640.1 - 6.1e-14 51.9 0.7 5.8e-07 29.6 0.2 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 GBG75640.1 - 0.0047 17.0 0.7 2.2 8.4 0.1 2.3 2 0 0 2 2 2 2 RNA binding motif PHM7_cyt PF14703.6 GBG75640.1 - 0.0052 17.0 0.5 0.52 10.5 0.5 3.0 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 GBG75640.1 - 0.0074 16.3 0.2 1.7 8.7 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 GBG75640.1 - 0.14 12.1 0.1 1.7 8.7 0.1 2.1 2 0 0 2 2 2 0 RL domain MciZ PF13072.6 GBG75640.1 - 0.22 11.4 0.1 16 5.4 0.1 2.3 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ PAS_5 PF07310.13 GBG75641.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 PAS domain DUF659 PF04937.15 GBG75642.1 - 5.6e-18 65.2 0.0 9.1e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG75642.1 - 1.1e-05 25.2 0.1 0.00015 21.5 0.4 2.6 2 1 0 2 2 2 1 hAT family C-terminal dimerisation region BRO1 PF03097.18 GBG75643.1 - 3.8e-108 361.8 2.8 3.8e-108 361.8 2.8 2.2 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GBG75643.1 - 1.7e-55 188.4 8.4 1.7e-55 188.4 8.4 3.3 3 1 0 3 3 3 1 ALIX V-shaped domain binding to HIV T6PP_N PF18572.1 GBG75643.1 - 0.015 15.1 6.9 0.058 13.2 0.6 3.1 3 0 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF1829 PF08862.10 GBG75643.1 - 0.07 13.6 1.0 0.39 11.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF1829 IL22 PF14565.6 GBG75643.1 - 0.09 13.0 0.8 0.92 9.8 0.5 2.4 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor HutP PF09021.11 GBG75643.1 - 0.44 10.9 1.9 1.6 9.1 0.1 2.4 2 0 0 2 2 2 0 HutP Med29 PF11568.8 GBG75643.1 - 0.87 9.8 6.0 0.29 11.3 1.9 2.4 2 0 0 2 2 2 0 Mediator complex subunit 29 Med28 PF11594.8 GBG75643.1 - 3.2 7.8 8.5 0.33 11.0 1.1 2.9 3 1 0 3 3 3 0 Mediator complex subunit 28 Histone PF00125.24 GBG75644.1 - 9.8e-09 35.7 1.1 2.6e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Methyltransf_16 PF10294.9 GBG75645.1 - 2.5e-19 69.7 0.0 9.8e-15 54.7 0.0 2.6 2 0 0 2 2 2 2 Lysine methyltransferase Sld5 PF05916.11 GBG75645.1 - 0.00013 22.3 0.1 0.00026 21.4 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein Methyltransf_16 PF10294.9 GBG75646.1 - 2.4e-19 69.7 0.1 8.3e-15 55.0 0.0 2.6 1 1 1 2 2 2 2 Lysine methyltransferase Sld5 PF05916.11 GBG75646.1 - 0.00013 22.4 0.1 0.00025 21.5 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein Myb_DNA-bind_4 PF13837.6 GBG75647.1 - 8.9e-12 45.2 2.8 8.9e-12 45.2 2.8 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG75647.1 - 0.056 13.7 1.3 0.11 12.7 1.3 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG75647.1 - 0.14 12.3 1.2 0.31 11.1 1.2 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Apolipoprotein PF01442.18 GBG75647.1 - 0.36 10.7 3.2 1.7 8.5 0.9 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Myb_DNA-bind_4 PF13837.6 GBG75648.1 - 1.4e-09 38.2 0.7 1.4e-09 38.2 0.7 3.6 4 0 0 4 4 4 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG75648.1 - 0.0012 18.9 1.3 0.0093 16.0 0.6 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG75648.1 - 0.0023 18.2 0.5 0.0075 16.6 0.5 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like KIAA1430 PF13879.6 GBG75648.1 - 0.068 13.9 0.9 8 7.3 0.0 2.5 2 0 0 2 2 2 0 KIAA1430 homologue Myb_DNA-bind_4 PF13837.6 GBG75649.1 - 1.1e-09 38.6 0.7 1.1e-09 38.6 0.7 3.1 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG75649.1 - 0.00099 19.1 1.3 0.0074 16.3 0.6 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG75649.1 - 0.002 18.4 0.5 0.0059 16.9 0.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like PP2 PF14299.6 GBG75650.1 - 8.2e-20 71.3 0.6 1.1e-19 70.9 0.6 1.2 1 0 0 1 1 1 1 Phloem protein 2 DUF4666 PF15697.5 GBG75650.1 - 0.016 15.8 0.1 0.037 14.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) DUF659 PF04937.15 GBG75651.1 - 1.8e-19 70.1 0.0 2.6e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3619 PF12279.8 GBG75652.1 - 0.29 11.5 5.1 2.6 8.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Noc2 PF03715.13 GBG75653.1 - 1.3e-108 362.8 0.0 2.2e-108 362.0 0.0 1.4 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 GBG75653.1 - 0.065 11.4 0.0 0.065 11.4 0.0 5.0 4 1 1 5 5 5 0 Nop14-like family Na_trans_assoc PF06512.13 GBG75653.1 - 0.2 11.9 0.0 0.2 11.9 0.0 4.1 3 1 1 4 4 4 0 Sodium ion transport-associated Phosphodiest PF01663.22 GBG75654.1 - 1.8e-73 248.2 0.5 2.1e-41 142.7 0.0 2.6 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase RT_RNaseH_2 PF17919.1 GBG75654.1 - 5.7e-30 103.3 0.0 2.3e-29 101.4 0.0 2.1 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75654.1 - 2.2e-29 101.8 0.1 7.2e-29 100.2 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75654.1 - 1.4e-25 90.2 0.1 3.3e-25 88.9 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75654.1 - 1.9e-19 69.5 0.5 4.8e-19 68.2 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Sulfatase PF00884.23 GBG75654.1 - 5.4e-11 42.4 0.0 4.8e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Sulfatase zf-H2C2 PF09337.10 GBG75654.1 - 0.001 19.2 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF229 PF02995.17 GBG75654.1 - 0.001 17.7 0.4 0.0046 15.6 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 GBG75654.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF1501 PF07394.12 GBG75654.1 - 0.05 12.7 0.0 0.05 12.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1501) REV PF00424.18 GBG75654.1 - 1.1 9.3 3.4 1.9 8.6 0.4 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF2950 PF11453.8 GBG75654.1 - 2.4 7.3 10.1 4.1 6.5 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) RVT_1 PF00078.27 GBG75655.1 - 5.5e-34 117.6 0.1 8.8e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SRP40_C PF05022.12 GBG75655.1 - 1.3e-23 83.6 2.9 1.3e-23 83.6 2.9 7.3 8 1 1 9 9 9 1 SRP40, C-terminal domain rve PF00665.26 GBG75655.1 - 2.4e-14 53.5 0.0 4.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG75655.1 - 8.7e-08 32.0 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75655.1 - 0.0015 18.3 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75655.1 - 0.003 18.1 0.0 0.024 15.2 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75655.1 - 0.017 15.7 0.0 0.049 14.3 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease LisH_TPL PF17814.1 GBG75655.1 - 0.041 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 LisH-like dimerisation domain eIF-1a PF01176.19 GBG75655.1 - 0.063 13.1 0.1 0.21 11.4 0.1 1.9 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 PCO_ADO PF07847.12 GBG75655.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 PCO_ADO ACTH_assoc PF16102.5 GBG75656.1 - 4.7 8.2 6.4 49 5.0 0.1 3.6 3 0 0 3 3 3 0 ACTH-associated domain zf-HIT PF04438.16 GBG75657.1 - 8.6e-06 25.5 1.1 8.6e-06 25.5 1.1 3.4 4 0 0 4 4 4 1 HIT zinc finger zf-CCHC PF00098.23 GBG75657.1 - 0.0039 17.2 2.0 0.0039 17.2 2.0 3.7 4 0 0 4 4 4 1 Zinc knuckle Toprim_C_rpt PF13368.6 GBG75657.1 - 0.0084 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Topoisomerase C-terminal repeat CDC45 PF02724.14 GBG75657.1 - 0.6 8.3 13.2 0.86 7.8 13.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG75657.1 - 2.1 6.5 17.0 3 6.0 17.0 1.2 1 0 0 1 1 1 0 Nop14-like family TP6A_N PF04406.14 GBG75658.1 - 8.3e-20 70.5 0.4 1.5e-19 69.8 0.4 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase HALZ PF02183.18 GBG75658.1 - 0.16 12.2 4.9 3.1 8.1 0.0 3.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper TraE PF05309.11 GBG75658.1 - 0.35 10.2 1.4 0.63 9.4 1.4 1.3 1 0 0 1 1 1 0 TraE protein Phage_GP20 PF06810.11 GBG75658.1 - 1.6 8.5 7.1 1.3 8.8 4.9 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 Lzipper-MIP1 PF14389.6 GBG75658.1 - 1.9 8.9 12.1 12 6.3 6.2 2.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4600 PF15372.6 GBG75658.1 - 2.4 8.6 9.3 0.68 10.4 4.4 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4600) DUF4407 PF14362.6 GBG75658.1 - 6.4 6.0 18.6 9.9 5.4 11.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4472 PF14739.6 GBG75658.1 - 9.9 6.9 13.3 0.82 10.4 3.5 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Branch PF02485.21 GBG75659.1 - 5.6e-79 265.1 0.1 7.6e-79 264.7 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme zf-RING_2 PF13639.6 GBG75660.1 - 0.00085 19.6 0.4 0.00085 19.6 0.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 GBG75660.1 - 0.012 15.9 0.0 0.042 14.1 0.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GBG75660.1 - 1.4 9.0 4.2 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG75660.1 - 1.9 8.5 6.3 0.17 11.8 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FXR_C3 PF16097.5 GBG75660.1 - 5.4 7.8 7.7 0.66 10.7 1.4 2.8 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 Beta_helix PF13229.6 GBG75662.1 - 5.2e-11 42.6 17.4 3.8e-06 26.8 6.4 2.6 1 1 1 2 2 2 2 Right handed beta helix region K_channel_TID PF07941.11 GBG75662.1 - 0.48 10.9 6.0 1.3 9.5 6.0 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RT_RNaseH_2 PF17919.1 GBG75663.1 - 2e-32 111.2 0.0 6.4e-32 109.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75663.1 - 2.8e-30 105.5 0.0 5.2e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75663.1 - 5.6e-28 97.3 0.0 1.5e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75663.1 - 3.8e-17 62.1 0.2 1e-16 60.7 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Snapin_Pallidin PF14712.6 GBG75663.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.8 1 1 0 2 2 2 0 Snapin/Pallidin FSA_C PF10479.9 GBG75664.1 - 0.07 11.3 0.3 0.088 10.9 0.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Solute_trans_a PF03619.16 GBG75665.1 - 7.5e-36 124.0 0.1 1.1e-35 123.5 0.1 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha UAA PF08449.11 GBG75665.1 - 0.03 13.5 0.1 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 UAA transporter family Cytochrom_B_N_2 PF13631.6 GBG75665.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Solute_trans_a PF03619.16 GBG75666.1 - 2e-71 240.7 3.0 2.3e-71 240.4 3.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4199 PF13858.6 GBG75666.1 - 0.039 14.3 0.6 0.093 13.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) MARVEL PF01284.23 GBG75666.1 - 2.1 8.4 9.5 0.036 14.1 2.0 1.8 2 0 0 2 2 2 0 Membrane-associating domain zf-C3Hc3H PF13891.6 GBG75667.1 - 3.6e-13 49.7 0.6 8.3e-13 48.5 0.6 1.6 1 0 0 1 1 1 1 Potential DNA-binding domain Dscam_C PF12355.8 GBG75667.1 - 2.4 9.2 7.4 0.27 12.2 2.5 2.0 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Glyco_transf_29 PF00777.18 GBG75668.1 - 4.4e-35 121.4 0.0 2.4e-33 115.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Toxin_5 PF05294.13 GBG75668.1 - 0.067 13.6 7.0 0.15 12.5 7.0 1.6 1 0 0 1 1 1 0 Scorpion short toxin EGF_2 PF07974.13 GBG75668.1 - 3.4 8.1 11.2 6.6 7.2 11.2 1.4 1 0 0 1 1 1 0 EGF-like domain RVT_1 PF00078.27 GBG75669.1 - 2.3e-30 105.8 0.1 9.1e-30 103.8 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG75669.1 - 1.6e-07 31.8 0.0 8.6e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75669.1 - 2.1e-06 28.2 0.0 6.8e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG75669.1 - 3.1e-05 23.8 0.0 6.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75669.1 - 0.00068 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG75669.1 - 0.0022 18.2 0.1 0.0022 18.2 0.1 3.6 4 0 0 4 4 4 1 Retrotransposon gag protein Fzo_mitofusin PF04799.13 GBG75669.1 - 0.82 9.2 5.0 59 3.2 0.0 3.2 3 0 0 3 3 3 0 fzo-like conserved region BLOC1_2 PF10046.9 GBG75669.1 - 2.4 8.5 6.1 2.4 8.5 1.5 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GBG75669.1 - 2.4 8.7 4.3 2.4 8.7 0.2 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CBP4 PF07960.11 GBG75669.1 - 6.1 6.7 5.7 2.4 8.0 2.8 1.8 1 1 1 2 2 2 0 CBP4 Chromo PF00385.24 GBG75670.1 - 0.00063 19.6 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HMG_box PF00505.19 GBG75671.1 - 3.1e-09 37.1 0.0 3.1e-09 37.1 0.0 1.8 2 0 0 2 2 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GBG75671.1 - 5.3e-07 30.1 0.0 5.3e-07 30.1 0.0 2.6 2 0 0 2 2 1 1 HMG-box domain AAA_23 PF13476.6 GBG75671.1 - 0.0017 18.9 8.4 0.0029 18.1 8.4 1.3 1 0 0 1 1 1 1 AAA domain CHDNT PF08073.12 GBG75671.1 - 0.0025 17.7 0.1 0.0097 15.8 0.0 1.9 2 0 0 2 2 2 1 CHDNT (NUC034) domain FXR_C1 PF16096.5 GBG75671.1 - 0.028 14.6 2.4 0.076 13.2 2.4 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 FAM91_C PF14648.6 GBG75671.1 - 0.066 12.0 7.1 0.096 11.5 7.1 1.2 1 0 0 1 1 1 0 FAM91 C-terminus Band_3_cyto PF07565.13 GBG75671.1 - 0.19 11.5 12.9 0.32 10.7 12.9 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM60A PF15396.6 GBG75671.1 - 0.22 11.5 8.8 0.35 10.8 8.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.17 GBG75671.1 - 0.23 11.6 11.1 0.45 10.6 11.1 1.5 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.6 GBG75671.1 - 0.53 10.5 8.2 1.1 9.5 8.2 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 GBG75671.1 - 0.85 8.6 14.2 1.1 8.2 14.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 GBG75671.1 - 1.3 8.4 14.6 2 7.8 14.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 GBG75671.1 - 1.7 6.8 44.4 0.056 11.7 37.3 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 EOS1 PF12326.8 GBG75671.1 - 2.2 8.2 4.4 3.6 7.5 4.4 1.4 1 0 0 1 1 1 0 N-glycosylation protein Plasmodium_Vir PF05795.11 GBG75671.1 - 6.9 6.0 6.2 11 5.3 6.2 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1980 PF09323.10 GBG75671.1 - 8.7 6.2 8.1 16 5.3 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) GREB1 PF15782.5 GBG75671.1 - 9.5 3.2 18.9 12 2.8 18.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Skp1_POZ PF03931.15 GBG75672.1 - 4.4e-09 36.4 0.0 1.2e-08 35.0 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain RTX_C PF08339.10 GBG75672.1 - 0.048 13.7 0.1 0.057 13.5 0.1 1.2 1 1 0 1 1 1 0 RTX C-terminal domain BTB PF00651.31 GBG75672.1 - 0.11 12.8 0.3 0.2 11.9 0.3 1.5 1 1 0 1 1 1 0 BTB/POZ domain Bac_surface_Ag PF01103.23 GBG75673.1 - 5.1e-30 105.1 0.1 6.2e-30 104.8 0.1 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 GBG75673.1 - 7e-06 26.5 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Surface antigen variable number repeat RT_RNaseH_2 PF17919.1 GBG75674.1 - 7.7e-31 106.1 0.0 6.1e-15 55.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75674.1 - 7.5e-30 103.3 0.0 1.6e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75674.1 - 4.1e-14 52.4 0.0 2.1e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG75674.1 - 0.0026 17.9 0.0 0.0055 16.9 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Metallophos PF00149.28 GBG75675.1 - 1.1e-11 45.7 0.1 2.1e-11 44.7 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GBG75675.1 - 0.084 13.1 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain PHD_Oberon PF07227.11 GBG75678.1 - 1.4e-30 105.8 23.8 3.5e-30 104.5 23.8 1.7 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein Oberon_cc PF16312.5 GBG75678.1 - 3.7e-24 85.1 21.5 3.7e-24 85.1 21.5 1.8 2 0 0 2 2 2 1 Coiled-coil region of Oberon CENP-B_dimeris PF09026.10 GBG75679.1 - 0.021 15.2 0.0 0.027 14.9 0.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.19 GBG75679.1 - 0.023 15.3 7.2 0.031 14.8 7.2 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein ORC_WH_C PF18137.1 GBG75679.1 - 0.032 14.3 0.6 0.039 14.0 0.6 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal TYW3 PF02676.14 GBG75679.1 - 0.058 12.7 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF3824 PF12868.7 GBG75679.1 - 0.086 13.5 0.4 0.12 13.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Porph_ging PF09697.10 GBG75679.1 - 0.14 12.7 1.8 0.21 12.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) ERG4_ERG24 PF01222.17 GBG75680.1 - 1.7e-41 142.4 8.6 4.4e-24 85.0 0.3 3.1 3 0 0 3 3 3 3 Ergosterol biosynthesis ERG4/ERG24 family DUF659 PF04937.15 GBG75680.1 - 4.8e-15 55.7 0.0 8.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG75680.1 - 0.03 14.1 0.1 0.063 13.1 0.1 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Alg14 PF08660.11 GBG75681.1 - 6.9e-57 192.2 0.1 1.6e-54 184.5 0.1 2.2 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Alg14 PF08660.11 GBG75682.1 - 6.2e-57 192.3 0.1 1.4e-40 139.1 0.1 2.2 1 1 1 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like Aminotran_3 PF00202.21 GBG75684.1 - 9.7e-88 294.5 0.1 3e-87 292.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-III RT_RNaseH_2 PF17919.1 GBG75684.1 - 3.2e-27 94.5 0.1 9.6e-27 93.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75684.1 - 1.2e-22 80.2 0.0 2.1e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75684.1 - 7.8e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG75684.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease BUD22 PF09073.10 GBG75684.1 - 4.1 6.6 31.7 8.2 5.6 31.7 1.4 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG75684.1 - 4.9 5.3 19.9 7.9 4.6 19.9 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG75684.1 - 6 6.2 30.8 14 5.0 30.8 1.6 1 0 0 1 1 1 0 SDA1 Aminotran_3 PF00202.21 GBG75685.1 - 9.7e-88 294.5 0.1 3e-87 292.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-III RT_RNaseH_2 PF17919.1 GBG75685.1 - 3.2e-27 94.5 0.1 9.6e-27 93.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75685.1 - 1.2e-22 80.2 0.0 2.1e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75685.1 - 7.8e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG75685.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease BUD22 PF09073.10 GBG75685.1 - 4.1 6.6 31.7 8.2 5.6 31.7 1.4 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG75685.1 - 4.9 5.3 19.9 7.9 4.6 19.9 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG75685.1 - 6 6.2 30.8 14 5.0 30.8 1.6 1 0 0 1 1 1 0 SDA1 PPR PF01535.20 GBG75686.1 - 1.9e-39 131.2 5.6 1.8e-05 24.7 0.1 9.1 9 0 0 9 9 9 7 PPR repeat PPR_1 PF12854.7 GBG75686.1 - 6.5e-36 121.7 1.2 6.9e-10 38.5 0.1 7.5 7 1 1 8 8 8 6 PPR repeat PPR_2 PF13041.6 GBG75686.1 - 1.4e-35 121.2 0.1 6.1e-08 32.7 0.0 8.1 6 2 3 9 9 9 6 PPR repeat family PPR_3 PF13812.6 GBG75686.1 - 3.5e-19 68.6 0.1 0.041 14.0 0.0 6.9 4 2 3 7 7 7 6 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG75686.1 - 2e-09 37.1 0.0 0.00074 18.9 0.0 3.1 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP CBS PF00571.28 GBG75686.1 - 5.3e-05 23.6 1.1 0.023 15.1 0.0 4.2 4 0 0 4 4 4 1 CBS domain TPR_14 PF13428.6 GBG75686.1 - 0.00023 21.7 3.5 8.6 7.5 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG75686.1 - 0.00026 21.5 4.5 4.9 7.7 0.1 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat PAP_fibrillin PF04755.12 GBG75687.1 - 1.1e-14 54.9 0.0 1.4e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin zf-CCHC PF00098.23 GBG75688.1 - 0.0024 17.8 1.4 0.0061 16.6 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG75688.1 - 0.013 15.3 0.1 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG75688.1 - 0.11 12.3 0.8 0.23 11.2 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle NDUF_B5 PF09781.9 GBG75688.1 - 0.25 10.9 0.9 0.71 9.4 0.9 1.8 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Transferase PF02458.15 GBG75688.1 - 0.74 8.4 3.0 3 6.4 0.0 2.3 2 0 0 2 2 2 0 Transferase family zf-CCHC_5 PF14787.6 GBG75688.1 - 1.6 8.5 3.8 0.55 10.0 0.4 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF87 PF01935.17 GBG75688.1 - 5.2 7.1 9.9 0.37 10.8 1.8 2.3 2 1 0 2 2 2 0 Helicase HerA, central domain Pectinesterase PF01095.19 GBG75689.1 - 6.2e-79 264.8 0.4 1e-78 264.1 0.4 1.3 1 0 0 1 1 1 1 Pectinesterase PMEI PF04043.15 GBG75689.1 - 1.6e-06 28.5 6.9 4.7e-06 27.0 6.9 1.8 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor TPR_4 PF07721.14 GBG75690.1 - 0.13 12.9 4.9 4.2 8.3 0.7 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec8_exocyst PF04048.14 GBG75693.1 - 0.021 14.7 7.8 0.11 12.4 1.5 2.8 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain TACC_C PF05010.14 GBG75693.1 - 0.095 12.5 14.7 0.62 9.8 2.2 2.7 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Abhydrolase_1 PF00561.20 GBG75693.1 - 0.15 11.7 0.3 0.48 10.0 0.1 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2408 PF10303.9 GBG75693.1 - 0.46 11.1 10.1 0.47 11.0 2.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) YabA PF06156.13 GBG75693.1 - 1.3 9.7 7.5 23 5.7 2.6 2.9 3 0 0 3 3 3 0 Initiation control protein YabA AAA PF00004.29 GBG75694.1 - 8.5e-36 123.3 0.0 1.5e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG75694.1 - 2.9e-09 36.6 0.1 6.1e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GBG75694.1 - 3.9e-05 23.5 0.0 7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 GBG75694.1 - 0.00046 19.4 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 GBG75694.1 - 0.00051 19.4 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 GBG75694.1 - 0.00074 19.5 0.4 0.013 15.4 0.4 2.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GBG75694.1 - 0.00083 19.8 0.1 0.0028 18.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GBG75694.1 - 0.00083 19.4 0.0 0.0028 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GBG75694.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GBG75694.1 - 0.0021 18.6 0.0 0.026 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain LisH PF08513.11 GBG75694.1 - 0.0026 17.7 0.1 0.005 16.8 0.1 1.4 1 0 0 1 1 1 1 LisH AAA_7 PF12775.7 GBG75694.1 - 0.004 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 GBG75694.1 - 0.0046 17.0 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GBG75694.1 - 0.0046 16.4 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GBG75694.1 - 0.0057 16.3 0.1 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GBG75694.1 - 0.0065 16.8 0.3 0.035 14.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GBG75694.1 - 0.01 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 GBG75694.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GBG75694.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 GBG75694.1 - 0.013 14.6 0.1 0.025 13.6 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 GBG75694.1 - 0.017 14.9 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 GBG75694.1 - 0.026 14.2 0.0 0.34 10.6 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.6 GBG75694.1 - 0.037 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 GBG75694.1 - 0.057 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Vps4_C PF09336.10 GBG75694.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 GBG75694.1 - 0.067 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 GBG75694.1 - 0.13 11.5 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 GBG75694.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 GBG75694.1 - 0.17 11.2 0.1 0.76 9.1 0.1 1.9 1 1 1 2 2 2 0 KaiC DsbD_2 PF13386.6 GBG75695.1 - 2.8e-05 24.1 6.5 2.8e-05 24.1 6.5 2.5 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region V-SNARE_C PF12352.8 GBG75696.1 - 3.4e-14 52.9 3.7 4.2e-14 52.6 3.7 1.1 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GBG75696.1 - 3.9e-06 26.7 0.0 4.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Sec20 Tweety PF04906.13 GBG75696.1 - 3.7e-05 22.6 0.1 4.3e-05 22.4 0.1 1.0 1 0 0 1 1 1 1 Tweety Collectrin PF16959.5 GBG75696.1 - 0.033 13.9 0.1 0.047 13.5 0.1 1.3 1 1 0 1 1 1 0 Renal amino acid transporter DUF2383 PF09537.10 GBG75696.1 - 0.034 14.5 0.2 0.049 14.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) baeRF_family10 PF18854.1 GBG75696.1 - 0.041 14.1 0.9 0.047 13.9 0.9 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 RT_RNaseH_2 PF17919.1 GBG75698.1 - 4.6e-26 90.8 0.0 7.2e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75698.1 - 4.5e-23 81.5 0.0 7.2e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75698.1 - 2.3e-09 37.1 0.1 3.2e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Uricase PF01014.18 GBG75700.1 - 7.5e-41 139.5 0.1 2.2e-28 99.1 0.0 2.0 2 0 0 2 2 2 2 Uricase RVT_1 PF00078.27 GBG75701.1 - 4.8e-38 130.9 0.0 3.5e-28 98.6 0.0 3.0 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75701.1 - 1.5e-16 60.2 0.1 1.1e-15 57.4 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG75701.1 - 1.1e-08 35.3 0.0 3.8e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-RVT PF13966.6 GBG75701.1 - 6.3e-05 23.6 6.5 0.00017 22.3 5.4 2.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-H2C2 PF09337.10 GBG75701.1 - 6.7e-05 23.0 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG75702.1 - 1.2e-28 100.2 0.0 2e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG75702.1 - 2.9e-05 24.7 5.4 0.0001 22.9 5.4 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Pyrophosphatase PF00719.19 GBG75703.1 - 2.7e-45 154.0 0.2 3.5e-45 153.7 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DDE_Tnp_4 PF13359.6 GBG75704.1 - 3.1e-20 72.4 0.0 7e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75704.1 - 3.1e-12 46.5 0.0 7.2e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Plant transposon protein NEMO PF11577.8 GBG75704.1 - 0.0018 18.3 1.1 0.0037 17.2 1.1 1.5 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO MAR_sialic_bdg PF10564.9 GBG75704.1 - 0.008 16.2 1.5 0.079 13.0 1.2 2.4 2 1 1 3 3 3 1 Sialic-acid binding micronemal adhesive repeat ZapB PF06005.12 GBG75704.1 - 0.021 15.3 5.5 2 8.9 4.0 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Cep57_CLD PF14073.6 GBG75704.1 - 0.084 12.9 2.2 0.13 12.3 2.2 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DivIC PF04977.15 GBG75704.1 - 0.29 10.9 4.2 0.62 9.9 0.7 2.3 2 0 0 2 2 2 0 Septum formation initiator CCDC106 PF15794.5 GBG75704.1 - 0.48 10.1 1.8 0.73 9.5 0.9 1.6 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 106 ADIP PF11559.8 GBG75704.1 - 0.5 10.4 6.5 0.26 11.4 2.8 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fcf1 PF04900.12 GBG75705.1 - 8.9e-42 141.5 2.8 1.3e-41 141.0 2.8 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 GBG75705.1 - 2.8e-12 47.0 0.0 4.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 GBG75705.1 - 0.054 13.8 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 NTF2 fold immunity protein TMEM171 PF15471.6 GBG75706.1 - 0.0052 15.8 0.4 0.052 12.5 0.0 2.1 2 0 0 2 2 2 1 Transmembrane protein family 171 BRE1 PF08647.11 GBG75707.1 - 0.011 15.8 2.1 0.011 15.8 2.1 2.3 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Peptidase_M29 PF02073.15 GBG75707.1 - 0.037 12.8 8.1 0.058 12.2 8.1 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) HYLS1_C PF15311.6 GBG75707.1 - 0.053 14.3 3.6 0.34 11.7 0.9 2.8 2 1 1 3 3 3 0 Hydrolethalus syndrome protein 1 C-terminus Endonuc-FokI_C PF09254.11 GBG75707.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal CDH1_2_SANT_HL1 PF18375.1 GBG75707.1 - 0.95 10.2 3.5 9.5 7.0 0.9 3.0 2 1 1 3 3 3 0 CDH1/2 SANT-Helical linker 1 CLZ PF16526.5 GBG75707.1 - 8.7 6.8 7.9 0.68 10.3 1.3 2.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AKAP7_NLS PF10469.9 GBG75708.1 - 6e-50 170.0 0.0 1.3e-46 159.1 0.0 2.3 2 0 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 GBG75708.1 - 9.7e-15 54.2 1.9 2.6e-06 27.2 0.1 2.6 2 0 0 2 2 2 2 KH domain MOEP19 PF16005.5 GBG75708.1 - 0.078 13.0 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 KH-like RNA-binding domain DUF1084 PF06454.11 GBG75709.1 - 7.1e-130 432.3 13.0 8.1e-130 432.1 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF4153 PF13687.6 GBG75709.1 - 0.00073 19.2 5.1 0.00073 19.2 5.1 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4153) DUF3975 PF13126.6 GBG75709.1 - 0.16 12.5 1.8 0.67 10.4 1.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3975) 7tm_3 PF00003.22 GBG75709.1 - 0.72 9.5 14.4 0.12 12.1 8.3 2.1 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR CD225 PF04505.12 GBG75709.1 - 3.8 7.7 8.6 7.1 6.9 0.4 3.4 3 1 0 3 3 3 0 Interferon-induced transmembrane protein RT_RNaseH_2 PF17919.1 GBG75711.1 - 9.8e-33 112.2 0.0 1.8e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75711.1 - 8.8e-32 110.4 0.1 1.5e-31 109.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75711.1 - 3.7e-29 101.1 0.0 7.3e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Cellulase PF00150.18 GBG75712.1 - 5.7e-09 35.8 0.5 8.4e-09 35.3 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RT_RNaseH_2 PF17919.1 GBG75713.1 - 6.2e-34 116.0 0.0 1.2e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75713.1 - 1.2e-30 106.7 0.1 2e-30 106.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75713.1 - 3.8e-30 104.3 0.0 8e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Imm32 PF15566.6 GBG75714.1 - 0.019 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 32 TT_ORF2 PF02957.15 GBG75714.1 - 0.045 14.7 2.7 9.1 7.2 0.8 2.4 2 0 0 2 2 2 0 TT viral ORF2 INTAP PF16617.5 GBG75714.1 - 0.1 12.9 0.1 0.49 10.8 0.0 2.0 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region CPBP PF02517.16 GBG75715.1 - 9.1e-09 35.6 0.4 9.1e-09 35.6 0.4 1.7 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease CDC27 PF09507.10 GBG75715.1 - 0.023 14.1 2.2 0.035 13.5 2.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.12 GBG75715.1 - 0.14 11.9 15.3 0.22 11.2 15.3 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF-3c_N PF05470.12 GBG75715.1 - 0.84 7.9 4.5 1.2 7.4 4.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus GCIP PF13324.6 GBG75715.1 - 1.2 8.7 3.0 1.6 8.3 3.0 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GBG75715.1 - 2.9 5.9 13.2 4 5.4 13.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG75715.1 - 3.7 5.6 7.7 5.1 5.2 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG75715.1 - 6.3 6.0 10.8 11 5.2 10.8 1.4 1 0 0 1 1 1 0 NOA36 protein SIS PF01380.22 GBG75716.1 - 2.1e-21 76.2 0.0 3.9e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 GBG75716.1 - 2.6e-17 63.0 2.1 2.7e-07 30.9 0.1 3.0 3 0 0 3 3 3 2 CBS domain SIS_2 PF13580.6 GBG75716.1 - 0.00023 21.2 0.0 0.0059 16.6 0.0 2.3 1 1 1 2 2 2 1 SIS domain DUF2529 PF10740.9 GBG75716.1 - 0.022 14.4 0.0 0.041 13.5 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2529) Corazonin PF17308.2 GBG75717.1 - 0.0029 18.0 13.6 0.12 12.7 1.4 2.4 2 0 0 2 2 2 2 Pro-corazonin Menin PF05053.13 GBG75717.1 - 0.068 11.5 11.4 0.14 10.5 11.4 1.5 1 0 0 1 1 1 0 Menin TLV_coat PF00429.19 GBG75718.1 - 0.091 11.4 1.1 0.18 10.5 1.1 1.4 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Atg14 PF10186.9 GBG75718.1 - 0.19 10.7 8.8 0.52 9.4 8.8 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4010 PF13194.6 GBG75719.1 - 0.09 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Excalibur PF05901.11 GBG75719.1 - 0.4 11.3 0.1 0.4 11.3 0.1 2.3 2 0 0 2 2 2 0 Excalibur calcium-binding domain Herpes_capsid PF06112.11 GBG75719.1 - 4.9 7.2 6.8 8.2 6.5 6.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Excalibur PF05901.11 GBG75720.1 - 0.28 11.8 0.1 0.28 11.8 0.1 2.2 2 0 0 2 2 2 0 Excalibur calcium-binding domain Herpes_capsid PF06112.11 GBG75720.1 - 2.7 8.0 6.4 4.4 7.4 6.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Histone PF00125.24 GBG75721.1 - 3.9e-23 82.2 1.0 9.1e-23 81.1 1.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG75721.1 - 0.063 13.7 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 CENP-S protein DUF1179 PF06678.11 GBG75721.1 - 0.67 10.0 2.1 1.4 8.9 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) adh_short PF00106.25 GBG75722.1 - 4.8e-32 111.0 0.1 1.2e-24 86.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GBG75722.1 - 6.9e-25 88.0 0.4 6.5e-18 65.1 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG75722.1 - 8.7e-09 35.5 0.3 1.4e-08 34.8 0.3 1.3 1 0 0 1 1 1 1 KR domain GST_N_5 PF18485.1 GBG75722.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RT_RNaseH_2 PF17919.1 GBG75723.1 - 1.8e-15 56.8 0.0 3.6e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75723.1 - 4e-11 42.8 0.1 6.2e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75723.1 - 0.0002 21.6 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG75723.1 - 7.3 4.7 10.2 10 4.3 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DOMON PF03351.17 GBG75724.1 - 4.9e-16 59.1 0.2 2.3e-09 37.5 0.0 3.0 2 1 0 2 2 2 2 DOMON domain DM13 PF10517.9 GBG75724.1 - 1.6e-07 31.8 0.0 3.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Electron transfer DM13 DUF568 PF04526.13 GBG75724.1 - 0.071 13.9 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF568) DUF2427 PF10348.9 GBG75724.1 - 0.42 10.4 6.6 0.045 13.5 1.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DOMON PF03351.17 GBG75725.1 - 6.8e-16 58.6 0.1 2.3e-09 37.5 0.0 3.0 2 1 0 2 2 2 2 DOMON domain DM13 PF10517.9 GBG75725.1 - 1.7e-07 31.8 0.0 3.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Electron transfer DM13 DUF568 PF04526.13 GBG75725.1 - 0.073 13.8 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF568) DUF2427 PF10348.9 GBG75725.1 - 0.45 10.3 6.6 0.046 13.5 1.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Exo_endo_phos PF03372.23 GBG75726.1 - 8.6e-12 45.1 1.0 1.8e-11 44.0 1.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG75726.1 - 0.00021 21.1 0.0 0.00054 19.8 0.0 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase R3H PF01424.22 GBG75727.1 - 9.8e-13 47.9 0.9 2.1e-12 46.8 0.9 1.6 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 GBG75727.1 - 2.7e-11 44.1 1.9 2.7e-11 44.1 1.9 2.3 2 0 0 2 2 2 1 SUZ domain MYO10_CC PF16735.5 GBG75727.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain ENT PF03735.14 GBG75729.1 - 2.1e-20 72.6 2.4 2.1e-20 72.6 2.4 1.6 2 0 0 2 2 2 1 ENT domain LBR_tudor PF09465.10 GBG75729.1 - 0.0013 18.4 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Latarcin PF10279.9 GBG75729.1 - 0.037 14.4 0.1 0.12 12.8 0.3 1.7 1 1 0 1 1 1 0 Latarcin precursor ENT PF03735.14 GBG75730.1 - 1.5e-20 73.0 2.4 1.5e-20 73.0 2.4 1.6 2 0 0 2 2 2 1 ENT domain LBR_tudor PF09465.10 GBG75730.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Latarcin PF10279.9 GBG75730.1 - 0.035 14.5 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 Latarcin precursor ENT PF03735.14 GBG75731.1 - 1.4e-20 73.1 2.4 1.4e-20 73.1 2.4 1.6 2 0 0 2 2 2 1 ENT domain LBR_tudor PF09465.10 GBG75731.1 - 0.009 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Latarcin PF10279.9 GBG75731.1 - 0.033 14.6 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 Latarcin precursor Spore_III_AB PF09548.10 GBG75731.1 - 0.16 12.1 0.2 0.33 11.1 0.2 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) p25-alpha PF05517.12 GBG75732.1 - 1.9 8.7 3.9 4.5 7.4 0.2 2.1 2 0 0 2 2 2 0 p25-alpha Pre-PUA PF17832.1 GBG75733.1 - 2.3e-25 89.1 0.0 2.3e-25 89.1 0.0 2.4 3 1 0 3 3 3 1 Pre-PUA-like domain DUF445 PF04286.12 GBG75733.1 - 0.052 13.4 1.3 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Vinculin PF01044.19 GBG75733.1 - 0.087 11.0 0.5 0.12 10.6 0.5 1.1 1 0 0 1 1 1 0 Vinculin family Prominin PF05478.11 GBG75733.1 - 0.092 10.7 1.5 0.13 10.2 1.5 1.1 1 0 0 1 1 1 0 Prominin SBDS_C PF09377.10 GBG75733.1 - 0.23 11.5 1.0 0.45 10.5 1.0 1.7 1 1 0 1 1 1 0 SBDS protein C-terminal domain OmpH PF03938.14 GBG75733.1 - 0.69 10.3 7.8 0.42 10.9 4.3 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HIP1_clath_bdg PF16515.5 GBG75733.1 - 6.4 7.5 10.3 2.4 8.8 7.2 1.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RNase_PH PF01138.21 GBG75734.1 - 2.3e-20 73.4 0.1 7.2e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GBG75734.1 - 4.4e-08 33.1 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NMT_C PF02799.15 GBG75737.1 - 1.5e-77 259.9 0.1 2.1e-77 259.4 0.1 1.1 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 GBG75737.1 - 6e-77 257.0 0.2 8.4e-77 256.5 0.2 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 GBG75737.1 - 0.00037 20.6 0.0 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GBG75737.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MutL_C PF08676.11 GBG75738.1 - 0.055 13.2 0.3 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 MutL C terminal dimerisation domain DUF4019 PF13211.6 GBG75738.1 - 0.057 13.8 2.9 1.3 9.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) Syntaxin-6_N PF09177.11 GBG75738.1 - 0.065 13.8 9.0 0.17 12.4 2.2 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Endotoxin_C2 PF18449.1 GBG75738.1 - 0.1 12.9 0.3 4.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Delta endotoxin Keratin_2_head PF16208.5 GBG75738.1 - 0.6 10.2 15.1 0.024 14.8 1.3 2.5 2 0 0 2 2 2 0 Keratin type II head Macoilin PF09726.9 GBG75738.1 - 8 4.9 16.5 0.086 11.4 2.4 2.5 3 0 0 3 3 3 0 Macoilin family DUF287 PF03384.14 GBG75739.1 - 5.1 7.6 5.7 1.8 9.0 1.3 2.3 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 RT_RNaseH_2 PF17919.1 GBG75740.1 - 7.6e-22 77.2 0.0 1.2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75740.1 - 8.9e-20 70.9 0.0 1.5e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75740.1 - 1.6e-18 66.5 0.3 3.1e-18 65.6 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG75740.1 - 1.3e-10 41.2 0.4 4.5e-10 39.4 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG75740.1 - 0.08 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger SRP68 PF16969.5 GBG75741.1 - 7.4e-143 477.5 4.7 8.6e-143 477.3 4.7 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 BRO1 PF03097.18 GBG75741.1 - 0.19 10.5 2.6 0.3 9.8 2.6 1.3 1 0 0 1 1 1 0 BRO1-like domain DDE_Tnp_4 PF13359.6 GBG75742.1 - 7.8e-20 71.1 0.0 1.4e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75742.1 - 1.2e-09 38.1 0.0 2.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein zf-RING_2 PF13639.6 GBG75742.1 - 2.3e-06 27.8 13.9 2.3e-06 27.8 13.9 3.3 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 GBG75742.1 - 2.9e-05 23.7 4.0 2.9e-05 23.7 4.0 2.4 2 0 0 2 2 1 1 RING-like zinc finger PHD PF00628.29 GBG75742.1 - 8.5e-05 22.4 11.8 8.5e-05 22.4 11.8 3.0 3 0 0 3 3 1 1 PHD-finger PHD_2 PF13831.6 GBG75742.1 - 0.00021 20.8 3.2 0.0013 18.2 3.2 2.6 1 0 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.25 GBG75742.1 - 0.0024 17.7 13.7 0.0024 17.7 13.7 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG75742.1 - 0.0035 17.1 14.8 0.017 14.9 14.8 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 GBG75742.1 - 0.0057 16.5 1.0 0.045 13.6 1.0 2.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 GBG75742.1 - 0.029 14.6 21.9 0.13 12.6 9.6 3.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GBG75742.1 - 0.75 9.9 23.6 0.011 15.8 8.2 3.8 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GBG75742.1 - 1.6 8.9 13.5 0.28 11.4 8.2 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 GBG75742.1 - 1.8 8.5 12.2 0.16 12.0 6.1 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Myb_DNA-bind_4 PF13837.6 GBG75743.1 - 4.3e-10 39.8 4.2 8e-10 39.0 4.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG75743.1 - 0.078 13.2 0.2 0.18 12.0 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain vATP-synt_AC39 PF01992.16 GBG75744.1 - 7.4e-117 390.6 0.7 8.3e-117 390.4 0.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit RVT_1 PF00078.27 GBG75745.1 - 0.00018 21.1 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4407 PF14362.6 GBG75745.1 - 2.7 7.3 7.2 11 5.3 5.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ABC1 PF03109.16 GBG75746.1 - 2.6e-11 43.7 0.1 0.00011 22.4 0.0 2.5 1 1 1 2 2 2 2 ABC1 family APH PF01636.23 GBG75746.1 - 0.046 13.6 0.1 0.54 10.1 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 GBG75747.1 - 2.1e-21 76.3 0.0 4.3e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GBG75747.1 - 0.0019 18.2 0.0 0.0059 16.6 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Citrate_synt PF00285.21 GBG75748.1 - 5.3e-11 42.2 0.1 0.00013 21.1 0.0 3.7 1 1 2 3 3 3 3 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 GBG75748.1 - 3e-10 40.1 0.0 5.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 GBG75748.1 - 0.00016 22.3 0.0 0.00036 21.2 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 GBG75748.1 - 0.00081 19.2 0.4 0.0021 17.9 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Occludin_ELL PF07303.13 GBG75749.1 - 5.3e-10 39.9 7.0 5.3e-10 39.9 7.0 2.8 2 1 0 2 2 2 1 Occludin homology domain 60KD_IMP PF02096.20 GBG75751.1 - 1.3e-31 109.7 0.4 1.8e-31 109.3 0.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein mTERF PF02536.14 GBG75754.1 - 2.7e-74 249.9 0.1 2.4e-69 233.7 0.1 3.4 3 1 0 3 3 3 3 mTERF NOA36 PF06524.12 GBG75754.1 - 2.2 7.5 7.2 5 6.4 7.2 1.5 1 0 0 1 1 1 0 NOA36 protein RT_RNaseH_2 PF17919.1 GBG75756.1 - 8.3e-30 102.8 0.0 2.1e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75756.1 - 6.2e-29 100.4 0.0 1.4e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG75756.1 - 0.26 10.9 0.0 0.26 10.9 0.0 2.6 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase U-box PF04564.15 GBG75757.1 - 3e-10 40.1 1.9 3.8e-10 39.8 0.1 2.1 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 GBG75757.1 - 0.0022 18.1 0.1 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 GBG75757.1 - 0.0045 16.8 0.2 0.012 15.4 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit F-box-like PF12937.7 GBG75760.1 - 2.3e-09 37.0 5.0 8.4e-09 35.2 0.7 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 GBG75760.1 - 9.6e-05 22.2 1.2 9.6e-05 22.2 1.2 2.8 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 GBG75760.1 - 0.022 14.8 10.5 1.3 9.2 0.0 6.2 8 0 0 8 8 8 0 Leucine Rich repeat Na_trans_cytopl PF11933.8 GBG75760.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytoplasmic domain of voltage-gated Na+ ion channel Acyltransferase PF01553.21 GBG75762.1 - 1.1e-28 99.5 0.0 1.6e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4389 PF14333.6 GBG75762.1 - 0.68 9.9 3.4 0.55 10.2 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) RNA_pol_Rpb1_5 PF04998.17 GBG75763.1 - 2.3e-84 283.0 0.3 4.1e-84 282.1 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 GBG75763.1 - 3.6e-77 259.8 1.4 7.6e-77 258.7 1.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 GBG75763.1 - 1.4e-73 246.6 0.0 3.5e-73 245.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_4 PF05000.17 GBG75763.1 - 2.2e-30 104.7 0.0 6.2e-30 103.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 GBG75763.1 - 3.7e-16 59.4 0.0 8.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 APG6_N PF17675.1 GBG75763.1 - 0.49 10.9 8.8 0.67 10.5 0.6 3.7 4 0 0 4 4 4 0 Apg6 coiled-coil region Prp19 PF08606.11 GBG75763.1 - 8.3 6.5 10.8 75 3.4 6.1 3.4 2 1 0 2 2 2 0 Prp19/Pso4-like RNA_pol_Rpb1_5 PF04998.17 GBG75764.1 - 3.6e-82 275.8 0.4 6.4e-82 275.0 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 GBG75764.1 - 3.6e-77 259.8 1.4 7.5e-77 258.7 1.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 GBG75764.1 - 1.4e-73 246.6 0.0 3.5e-73 245.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GBG75764.1 - 1.6e-33 115.9 0.0 3.4e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 APG6_N PF17675.1 GBG75764.1 - 0.48 10.9 8.8 0.67 10.5 0.6 3.7 4 0 0 4 4 4 0 Apg6 coiled-coil region Prp19 PF08606.11 GBG75764.1 - 8 6.5 10.8 75 3.4 6.1 3.4 2 1 0 2 2 2 0 Prp19/Pso4-like Asp_protease PF09668.10 GBG75766.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG75766.1 - 0.021 15.4 0.1 0.065 13.9 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease cNMP_binding PF00027.29 GBG75766.1 - 0.095 12.8 0.1 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain gag-asp_proteas PF13975.6 GBG75767.1 - 1.6e-05 25.4 0.1 3.7e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75767.1 - 0.00027 21.5 0.1 0.00055 20.5 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG75767.1 - 0.02 14.7 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG75767.1 - 0.44 10.7 1.9 0.98 9.6 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG75768.1 - 2.3e-09 37.5 1.5 6.9e-09 36.0 1.5 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG75768.1 - 0.0062 16.8 1.6 0.011 16.0 0.6 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Apt1 PF10351.9 GBG75769.1 - 4.5 6.0 13.4 5.3 5.8 13.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CTU2 PF10288.9 GBG75770.1 - 0.076 13.3 9.4 0.09 13.0 9.4 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 UBA2_C PF16195.5 GBG75770.1 - 0.086 13.5 15.8 0.1 13.3 15.8 1.0 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Med19 PF10278.9 GBG75770.1 - 0.49 10.3 25.9 0.53 10.2 25.9 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TRAP_alpha PF03896.16 GBG75770.1 - 0.61 9.2 11.0 0.7 9.1 11.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Connexin PF00029.19 GBG75770.1 - 0.64 9.7 16.5 0.66 9.7 16.5 1.0 1 0 0 1 1 1 0 Connexin Tim54 PF11711.8 GBG75770.1 - 0.82 8.4 21.1 0.89 8.3 21.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3408 PF11888.8 GBG75770.1 - 0.89 9.7 21.0 1.1 9.3 21.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) AIF_C PF14721.6 GBG75770.1 - 1.2 9.5 11.4 1.3 9.3 11.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FGF-BP1 PF06473.12 GBG75770.1 - 1.2 8.9 17.7 1.2 8.9 17.7 1.0 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RNA_pol_Rpc4 PF05132.14 GBG75770.1 - 1.2 9.5 16.4 1.4 9.3 16.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4820 PF16091.5 GBG75770.1 - 1.7 8.0 12.6 2 7.7 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4746 PF15928.5 GBG75770.1 - 1.9 7.9 18.6 1.9 7.8 18.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GNAT_acetyltr_2 PF13718.6 GBG75770.1 - 2.2 7.6 9.6 2.3 7.6 9.6 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CPSF100_C PF13299.6 GBG75770.1 - 2.6 8.2 17.2 2.9 8.0 17.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ureide_permease PF07168.11 GBG75770.1 - 3 6.5 11.9 3.1 6.4 11.9 1.0 1 0 0 1 1 1 0 Ureide permease SpoIIP PF07454.11 GBG75770.1 - 3.6 7.0 19.3 3.9 6.8 19.3 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SelP_N PF04592.14 GBG75770.1 - 3.6 6.9 12.6 4.3 6.7 12.6 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region V_ATPase_I PF01496.19 GBG75770.1 - 4.1 5.2 13.7 4.1 5.2 13.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_polI_A34 PF08208.11 GBG75770.1 - 5.1 7.1 41.3 5.7 7.0 41.3 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.10 GBG75770.1 - 5.7 7.2 27.9 6.4 7.1 27.9 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PTPRCAP PF15713.5 GBG75770.1 - 6.1 7.1 23.8 7.4 6.9 23.8 1.0 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated TFB6 PF17110.5 GBG75770.1 - 6.9 6.4 12.4 8.1 6.2 12.4 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Presenilin PF01080.17 GBG75770.1 - 7.3 5.2 15.9 8.6 5.0 15.9 1.1 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.19 GBG75770.1 - 7.8 5.3 9.9 8.6 5.1 9.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Coilin_N PF15862.5 GBG75770.1 - 8 6.3 27.2 9.1 6.1 27.2 1.1 1 0 0 1 1 1 0 Coilin N-terminus Herpes_DNAp_acc PF04929.12 GBG75770.1 - 8.1 5.3 14.1 8.6 5.2 14.1 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF1168 PF06658.12 GBG75770.1 - 8.1 6.3 34.1 9.4 6.0 34.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) GOLD_2 PF13897.6 GBG75770.1 - 9.7 6.7 10.1 13 6.3 10.1 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking GAGA_bind PF06217.12 GBG75771.1 - 1.9 8.7 12.3 2 8.6 12.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SLC12 PF03522.15 GBG75771.1 - 6.2 5.7 12.6 7.1 5.5 12.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PIEZO PF15917.5 GBG75771.1 - 8 5.9 21.3 9.5 5.6 21.3 1.1 1 0 0 1 1 1 0 Piezo HATPase_c PF02518.26 GBG75774.1 - 0.0001 22.8 0.0 0.00013 22.4 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ndc1_Nup PF09531.10 GBG75775.1 - 0.041 12.6 0.5 0.065 11.9 0.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 GBG75775.1 - 0.046 13.3 3.4 0.077 12.6 3.4 1.3 1 0 0 1 1 1 0 Spt20 family Exo70 PF03081.15 GBG75775.1 - 0.41 9.7 1.9 0.81 8.7 0.0 1.9 2 0 0 2 2 2 0 Exo70 exocyst complex subunit DUF4834 PF16118.5 GBG75775.1 - 0.42 11.6 3.7 1.4 9.9 3.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RT_RNaseH_2 PF17919.1 GBG75776.1 - 1.4e-31 108.5 0.0 3.7e-31 107.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75776.1 - 2.7e-28 98.3 0.1 1e-27 96.5 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75776.1 - 2.1e-18 66.2 0.0 4.6e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG75776.1 - 0.00031 20.9 0.0 0.00077 19.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG75776.1 - 0.005 17.0 0.1 0.016 15.4 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG75778.1 - 1.5e-05 24.6 0.0 4.1e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spt5_N PF11942.8 GBG75778.1 - 1.7 9.7 0.0 1.7 9.7 0.0 2.9 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DDE_Tnp_4 PF13359.6 GBG75780.1 - 4.7e-15 55.6 0.1 1.6e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75780.1 - 4.6e-08 32.9 0.0 7.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG75780.1 - 0.0058 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Nucleotid_trans PF03407.16 GBG75781.1 - 6.4e-05 23.0 0.0 0.00018 21.6 0.0 1.7 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase CDV3 PF15359.6 GBG75782.1 - 3 8.3 7.8 0.24 11.9 2.1 2.2 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 RT_RNaseH_2 PF17919.1 GBG75783.1 - 1.5e-32 111.6 0.0 2.9e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75783.1 - 2e-29 101.9 0.3 4.6e-29 100.8 0.3 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75783.1 - 4.9e-18 65.0 0.2 1.1e-17 63.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG75783.1 - 6e-05 22.7 0.3 0.00014 21.5 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG75783.1 - 0.0076 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG75783.1 - 0.013 15.7 0.4 0.069 13.4 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Peptidase_S64 PF08192.11 GBG75783.1 - 0.048 12.1 0.8 0.083 11.4 0.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 Noelin-1 PF12308.8 GBG75783.1 - 0.18 11.8 2.9 0.43 10.6 1.1 2.6 2 0 0 2 2 2 0 Neurogenesis glycoprotein zf-CCHC PF00098.23 GBG75783.1 - 1.2 9.3 4.9 3.3 8.0 4.9 1.8 1 0 0 1 1 1 0 Zinc knuckle Miga PF10265.9 GBG75783.1 - 1.9 7.4 5.3 3 6.7 5.3 1.2 1 0 0 1 1 1 0 Mitoguardin SRP-alpha_N PF04086.13 GBG75783.1 - 2 8.3 14.6 0.17 11.8 0.7 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal HHH_9 PF17674.1 GBG75783.1 - 4.3 8.3 6.1 12 6.9 1.3 3.4 2 1 1 3 3 2 0 HHH domain U-box PF04564.15 GBG75784.1 - 4.8e-09 36.3 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 GBG75784.1 - 8.2e-06 25.6 1.7 3.8e-05 23.4 1.7 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG75784.1 - 1.6e-05 24.9 4.2 0.00011 22.3 4.2 2.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GBG75784.1 - 9.3e-05 22.4 4.7 0.00034 20.6 4.7 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG75784.1 - 0.00015 21.6 2.3 0.00073 19.4 2.3 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG75784.1 - 0.00091 19.0 0.7 0.00091 19.0 0.7 2.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Arm PF00514.23 GBG75784.1 - 0.00098 19.1 8.0 59 3.9 0.0 9.7 11 0 0 11 11 10 0 Armadillo/beta-catenin-like repeat Baculo_IE-1 PF05290.11 GBG75784.1 - 0.0019 18.2 2.2 0.0019 18.2 2.2 2.5 3 0 0 3 3 3 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 GBG75784.1 - 0.0068 16.7 3.8 0.045 14.1 3.8 2.6 1 0 0 1 1 1 1 Ring finger domain RTP1_C1 PF10363.9 GBG75784.1 - 0.022 14.9 0.3 1.5 9.0 0.1 4.4 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Prok-RING_4 PF14447.6 GBG75784.1 - 0.04 13.8 4.4 0.022 14.6 1.7 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RVT_1 PF00078.27 GBG75785.1 - 1.9e-29 102.8 0.1 2.6e-29 102.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75785.1 - 9.8e-20 70.5 0.0 4.3e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75785.1 - 2.1e-09 37.6 0.0 7.4e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG75785.1 - 6.8e-07 29.8 0.0 1.3e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75785.1 - 5.1e-06 27.0 0.0 9.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG75785.1 - 4.2e-05 23.3 0.0 9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75785.1 - 0.00052 19.8 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease VHL PF01847.16 GBG75787.1 - 1.6e-20 72.8 0.0 2.2e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 VHL beta domain Integrase_H2C2 PF17921.1 GBG75788.1 - 2.4e-16 59.6 0.7 6.6e-16 58.2 0.7 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG75788.1 - 2.5e-16 59.9 0.0 9.4e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG75788.1 - 9.7e-06 25.8 3.6 0.00019 21.6 0.0 3.9 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG75788.1 - 0.0023 17.8 0.0 0.0058 16.5 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG75788.1 - 0.035 13.9 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 GBG75788.1 - 0.049 13.8 0.0 0.25 11.5 0.0 2.3 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 GBG75788.1 - 0.085 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger NYD-SP28_assoc PF14775.6 GBG75788.1 - 1.1 9.5 5.0 2 8.6 0.7 3.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain F-box-like PF12937.7 GBG75789.1 - 5e-07 29.5 0.3 1.1e-06 28.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG75789.1 - 0.00035 20.4 0.6 0.0011 18.7 0.6 1.9 1 1 0 1 1 1 1 F-box domain RR_TM4-6 PF06459.12 GBG75789.1 - 1 9.1 35.1 2.6 7.8 15.4 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 GBG75789.1 - 2.2 8.4 10.8 3.4 7.8 0.9 2.3 2 0 0 2 2 2 0 DDHD domain CDC45 PF02724.14 GBG75789.1 - 2.8 6.1 54.7 0.026 12.9 23.2 2.1 2 0 0 2 2 2 0 CDC45-like protein CLN3 PF02487.17 GBG75789.1 - 3 6.8 5.3 2.5 7.1 0.3 2.3 2 0 0 2 2 2 0 CLN3 protein CCSAP PF15748.5 GBG75789.1 - 3.9 7.6 30.1 4.2 7.5 13.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SDA1 PF05285.12 GBG75789.1 - 8.9 5.6 70.6 0.18 11.2 33.6 2.1 2 0 0 2 2 2 0 SDA1 DUF5066 PF16728.5 GBG75790.1 - 0.03 13.7 0.0 0.035 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) GP38 PF05268.11 GBG75791.1 - 4.8 6.7 13.2 8.1 6.0 13.2 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 RT_RNaseH_2 PF17919.1 GBG75792.1 - 1.5e-10 41.0 0.0 2.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75792.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG75793.1 - 0.18 12.2 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG75794.1 - 0.033 14.3 2.3 0.064 13.4 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG75794.1 - 0.081 12.6 0.2 0.22 11.2 0.2 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like SQS_PSY PF00494.19 GBG75795.1 - 7.4e-74 248.6 0.1 1.1e-73 248.0 0.1 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase gag-asp_proteas PF13975.6 GBG75796.1 - 0.00018 22.0 0.1 0.0004 20.9 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75796.1 - 0.002 18.7 0.1 0.0041 17.7 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG75796.1 - 0.036 13.9 0.1 0.061 13.1 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG75796.1 - 0.066 12.9 0.2 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like ERCC4 PF02732.15 GBG75797.1 - 9e-09 35.7 1.8 1.3e-07 31.9 1.8 2.4 1 1 0 1 1 1 1 ERCC4 domain Nitrate_red_del PF02613.15 GBG75797.1 - 0.022 14.7 0.3 0.022 14.7 0.3 2.3 2 0 0 2 2 2 0 Nitrate reductase delta subunit MMR1 PF08505.10 GBG75797.1 - 1.1 9.5 8.3 0.19 12.0 3.6 2.0 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF5401 PF17380.2 GBG75797.1 - 6 4.8 24.6 9.9 4.1 24.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Radial_spoke_3 PF06098.11 GBG75797.1 - 9.4 5.4 18.8 17 4.6 15.1 2.5 2 0 0 2 2 2 0 Radial spoke protein 3 RT_RNaseH PF17917.1 GBG75799.1 - 2.7e-20 72.6 0.0 2.5e-19 69.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75799.1 - 5e-19 68.2 0.0 1.9e-18 66.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75799.1 - 1.4e-08 34.5 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75799.1 - 3.2e-08 33.6 0.2 7.4e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75799.1 - 0.0086 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain WD40 PF00400.32 GBG75800.1 - 7.2e-13 48.8 6.3 0.0019 19.0 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40 PF00400.32 GBG75801.1 - 5.1e-13 49.3 12.0 0.00018 22.2 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 GBG75802.1 - 3.3e-31 108.5 0.0 3.7e-17 62.5 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 GBG75802.1 - 5.2e-29 101.4 0.0 7.4e-27 94.4 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Tctex-1 PF03645.13 GBG75802.1 - 5.8e-25 87.5 0.0 1.2e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Tctex-1 family Kinase-like PF14531.6 GBG75802.1 - 0.28 10.5 0.3 1.1 8.5 0.0 2.0 3 0 0 3 3 3 0 Kinase-like RVT_1 PF00078.27 GBG75803.1 - 1.1e-52 178.7 0.1 2.9e-30 105.4 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) FAD_binding_3 PF01494.19 GBG75803.1 - 5e-41 141.1 7.7 1.7e-27 96.6 0.0 3.8 4 0 0 4 4 4 2 FAD binding domain RT_RNaseH_2 PF17919.1 GBG75803.1 - 3.3e-36 123.3 0.0 1.9e-22 79.2 0.0 3.7 2 1 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75803.1 - 7.2e-25 87.3 0.0 3.7e-20 72.2 0.0 3.5 2 1 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75803.1 - 2.4e-16 59.5 2.5 3.9e-16 58.9 0.4 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG75803.1 - 0.00027 21.1 0.2 0.0021 18.2 0.2 2.4 2 0 0 2 2 2 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG75803.1 - 0.0023 18.2 0.3 0.015 15.6 0.3 2.4 1 0 0 1 1 1 1 Retrotransposon gag protein CDH1_2_SANT_HL1 PF18375.1 GBG75803.1 - 0.034 14.8 0.0 15 6.3 0.0 3.2 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 ZapB PF06005.12 GBG75803.1 - 0.078 13.4 0.1 0.078 13.4 0.1 3.7 4 0 0 4 4 3 0 Cell division protein ZapB CsgE PF10627.9 GBG75803.1 - 5.3 7.3 6.2 13 6.1 6.2 1.7 1 0 0 1 1 1 0 Curli assembly protein CsgE NPV_P10 PF05531.12 GBG75803.1 - 9.7 6.7 8.3 2.5 8.6 0.3 3.6 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Profilin PF00235.19 GBG75804.1 - 0.0087 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Profilin Robl_LC7 PF03259.17 GBG75804.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain Roughex PF06020.11 GBG75804.1 - 2 7.4 7.8 2.7 7.0 7.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein BUD22 PF09073.10 GBG75805.1 - 0.32 10.3 31.1 0.47 9.8 31.1 1.2 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG75805.1 - 1.5 8.3 17.6 1.9 7.9 17.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG75805.1 - 8.2 4.5 30.4 11 4.1 30.4 1.1 1 0 0 1 1 1 0 Nop14-like family ABC_tran PF00005.27 GBG75807.1 - 5.8e-25 88.4 0.0 1.3e-24 87.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG75807.1 - 8.4e-24 84.3 19.0 1.3e-23 83.7 19.0 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG75807.1 - 2.6e-11 43.9 0.0 6.2e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GBG75807.1 - 0.00016 22.2 0.3 0.00016 22.2 0.3 1.6 2 0 0 2 2 1 1 AAA domain ABC2_membrane PF01061.24 GBG75807.1 - 0.00061 19.3 19.0 0.00061 19.3 19.0 2.3 2 0 0 2 2 2 1 ABC-2 type transporter Rad17 PF03215.15 GBG75807.1 - 0.075 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 GBG75807.1 - 0.089 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GBG75807.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG75807.1 - 0.15 11.8 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 GBG75807.1 - 0.2 11.4 0.1 15 5.2 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 GBG75807.1 - 0.28 10.9 0.0 2.6 7.6 0.2 2.0 2 0 0 2 2 2 0 AAA ATPase domain RT_RNaseH_2 PF17919.1 GBG75808.1 - 8.4e-35 118.8 0.0 1.6e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75808.1 - 4.7e-31 107.2 0.1 1e-30 106.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75808.1 - 1.6e-19 69.7 1.7 3e-19 68.8 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG75808.1 - 4.1e-16 59.2 0.1 3.1e-15 56.4 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain rve_3 PF13683.6 GBG75808.1 - 0.099 12.4 0.0 0.31 10.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 GBG75808.1 - 0.15 12.3 1.9 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger Myco_haema PF05692.12 GBG75810.1 - 0.16 10.9 2.0 0.19 10.7 1.0 1.6 2 0 0 2 2 2 0 Mycoplasma haemagglutinin DUF2547 PF10818.8 GBG75810.1 - 1.3 10.0 4.1 0.74 10.8 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) RVT_1 PF00078.27 GBG75811.1 - 8.6e-28 97.4 0.3 1.5e-27 96.5 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75811.1 - 4.5e-21 75.1 0.0 8.3e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75811.1 - 5e-21 74.6 0.0 1.1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mito_carr PF00153.27 GBG75813.1 - 7.5e-63 208.5 8.9 3.3e-22 78.2 0.2 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Dynein_attach_N PF15867.5 GBG75814.1 - 6e-13 48.5 1.0 9.4e-13 47.9 1.0 1.2 1 0 0 1 1 1 1 Dynein attachment factor N-terminus CAP_N PF01213.19 GBG75815.1 - 2.8e-78 263.6 0.0 3.9e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 GBG75815.1 - 2e-51 173.8 0.4 3.1e-51 173.1 0.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 GBG75815.1 - 0.00084 19.1 1.2 0.0013 18.4 1.2 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C RVT_1 PF00078.27 GBG75816.1 - 5.1e-32 111.2 0.1 8.2e-32 110.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75816.1 - 8.9e-31 105.9 0.0 2.6e-15 56.3 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75816.1 - 5.3e-30 103.8 0.0 1.9e-29 102.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75816.1 - 1.1e-15 57.5 0.0 3.7e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG75816.1 - 1.3e-13 51.1 0.0 6.3e-13 49.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG75816.1 - 1.6e-05 25.0 0.0 3.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Cu_bind_like PF02298.17 GBG75817.1 - 1.9e-07 31.0 0.0 3.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Plastocyanin-like domain RVT_1 PF00078.27 GBG75818.1 - 1.4e-20 73.8 0.0 2.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG75818.1 - 3.4e-16 59.1 0.1 1.2e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG75818.1 - 3.5e-05 23.9 0.0 7.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG75818.1 - 0.0017 18.5 0.0 0.0045 17.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG75818.1 - 0.064 13.9 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease UCR_UQCRX_QCR9 PF05365.12 GBG75820.1 - 1.9e-19 69.4 0.0 2.1e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like PID_2 PF14719.6 GBG75820.1 - 0.049 13.5 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) CDC45 PF02724.14 GBG75822.1 - 0.14 10.4 19.4 0.21 9.8 19.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG75822.1 - 3.6 5.7 24.3 4.9 5.3 24.3 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG75823.1 - 9.4e-68 228.0 1.5 4.3e-36 124.5 0.1 3.3 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75823.1 - 3.4e-29 101.2 0.0 7.7e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75823.1 - 1.6e-28 98.7 0.0 4e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 GBG75823.1 - 1.8e-25 89.8 0.0 2.8e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG75823.1 - 1.8e-13 50.4 0.0 2.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Integrase_H2C2 PF17921.1 GBG75823.1 - 6.1e-13 48.7 0.9 6.1e-13 48.7 0.9 1.9 2 0 0 2 2 1 1 Integrase zinc binding domain Pkinase_fungal PF17667.1 GBG75823.1 - 7.3e-10 38.2 0.0 1.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG75823.1 - 0.00038 20.5 1.7 0.0026 17.7 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF4392 PF14336.6 GBG75823.1 - 0.031 13.7 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) zf-H2C2 PF09337.10 GBG75823.1 - 0.041 14.1 0.6 0.18 12.1 0.1 2.3 2 0 0 2 2 2 0 H2C2 zinc finger Baculo_p24 PF05073.12 GBG75823.1 - 0.077 12.8 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Baculovirus P24 capsid protein RPAP1_N PF08621.10 GBG75823.1 - 0.32 10.8 1.8 10 6.0 0.2 2.9 2 0 0 2 2 2 0 RPAP1-like, N-terminal Snapin_Pallidin PF14712.6 GBG75823.1 - 0.99 9.9 3.6 0.79 10.2 0.4 2.7 2 1 0 2 2 1 0 Snapin/Pallidin Phage_GPO PF05929.11 GBG75823.1 - 1.4 8.5 5.6 0.77 9.3 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase gag-asp_proteas PF13975.6 GBG75824.1 - 0.022 15.3 0.1 0.1 13.1 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75824.1 - 0.037 14.7 0.1 0.2 12.3 0.0 2.3 2 1 0 2 2 2 0 Aspartyl protease Spc24 PF08286.11 GBG75824.1 - 0.049 13.9 4.5 0.11 12.8 3.9 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 GBG75824.1 - 0.12 10.3 8.0 0.17 9.8 8.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF572 PF04502.13 GBG75824.1 - 1.8 8.1 18.0 2.8 7.5 18.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF913 PF06025.12 GBG75824.1 - 2.7 6.9 5.5 6.2 5.7 5.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RT_RNaseH_2 PF17919.1 GBG75825.1 - 1.2e-29 102.3 0.0 5.7e-29 100.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75825.1 - 7.1e-29 100.2 0.1 1.8e-28 98.8 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75825.1 - 2.3e-14 53.5 0.1 4.7e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG75825.1 - 0.053 13.1 0.0 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Integrase_H2C2 PF17921.1 GBG75826.1 - 1.7e-32 111.3 2.6 1.3e-17 63.6 0.2 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG75826.1 - 1.3e-28 100.0 0.0 2.2e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG75826.1 - 1.2e-27 96.4 0.5 4.2e-12 46.3 0.0 3.2 3 0 0 3 3 3 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG75826.1 - 7.4e-24 83.7 0.0 1.8e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75826.1 - 6e-12 45.8 0.0 1.8e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG75826.1 - 3e-07 30.3 0.0 5.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG75826.1 - 0.011 16.4 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG75826.1 - 0.019 15.5 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG75826.1 - 0.024 14.9 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 H2C2 zinc finger Dimer_Tnp_hAT PF05699.14 GBG75827.1 - 3.8e-11 42.6 0.1 9e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Dimer_Tnp_hAT PF05699.14 GBG75828.1 - 1.2e-05 25.0 0.2 3.2e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ADIP PF11559.8 GBG75828.1 - 8.8 6.4 16.7 0.16 12.0 0.4 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Dimer_Tnp_hAT PF05699.14 GBG75829.1 - 5.3e-06 26.1 0.2 1.1e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCHC PF00098.23 GBG75830.1 - 0.00039 20.4 0.7 0.001 19.0 0.7 1.8 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG75831.1 - 1.2e-91 306.2 6.3 5.5e-28 98.0 0.1 4.6 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75831.1 - 1.7e-80 266.1 8.0 5.9e-20 71.5 0.0 5.9 6 0 0 6 6 5 4 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75831.1 - 5.5e-80 263.8 3.6 1.3e-25 89.3 0.0 6.9 5 1 1 6 6 6 6 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75831.1 - 4.5e-67 222.0 2.7 2.7e-18 65.8 0.2 4.8 4 0 0 4 4 4 4 Integrase zinc binding domain rve PF00665.26 GBG75831.1 - 7.2e-26 90.7 0.0 3.7e-13 49.7 0.0 3.4 3 0 0 3 3 3 2 Integrase core domain Asp_protease_2 PF13650.6 GBG75831.1 - 3.6e-12 46.7 0.0 9e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG75831.1 - 9.2e-12 45.4 0.0 5.3e-05 23.7 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG75831.1 - 7.7e-10 38.8 0.0 0.41 10.9 0.0 4.7 4 0 0 4 4 4 3 H2C2 zinc finger RVP_2 PF08284.11 GBG75831.1 - 1e-08 35.0 0.0 0.0011 18.7 0.0 3.4 3 0 0 3 3 3 2 Retroviral aspartyl protease Rhamno_transf PF11316.8 GBG75831.1 - 0.004 16.6 0.3 0.35 10.2 0.0 3.0 2 0 0 2 2 2 1 Putative rhamnosyl transferase Asp_protease PF09668.10 GBG75831.1 - 0.0057 16.4 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG75831.1 - 0.074 12.8 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Putative peptidase (DUF1758) SH3_16 PF18348.1 GBG75831.1 - 0.087 12.6 0.0 5 7.0 0.0 2.9 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain HAUS6_N PF14661.6 GBG75831.1 - 0.55 9.8 5.7 1 8.9 0.8 3.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.15 GBG75831.1 - 7.5 6.4 12.9 6.1 6.7 1.4 3.1 2 0 0 2 2 2 0 Septum formation initiator RVT_1 PF00078.27 GBG75832.1 - 1.2e-91 306.2 6.3 5.5e-28 98.0 0.1 4.6 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75832.1 - 1.6e-80 266.2 8.0 5.9e-20 71.5 0.0 5.9 6 0 0 6 6 5 4 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75832.1 - 5.3e-80 263.9 3.6 1.3e-25 89.3 0.0 6.9 5 1 1 6 6 6 6 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75832.1 - 4.4e-67 222.1 2.7 2.7e-18 65.8 0.2 4.8 4 0 0 4 4 4 4 Integrase zinc binding domain rve PF00665.26 GBG75832.1 - 7.4e-26 90.7 0.0 3.6e-13 49.7 0.0 3.4 3 0 0 3 3 3 2 Integrase core domain Asp_protease_2 PF13650.6 GBG75832.1 - 3.6e-12 46.8 0.0 8.9e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG75832.1 - 9.1e-12 45.4 0.0 5.3e-05 23.7 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG75832.1 - 7.6e-10 38.9 0.0 0.4 10.9 0.0 4.7 4 0 0 4 4 4 3 H2C2 zinc finger RVP_2 PF08284.11 GBG75832.1 - 1e-08 35.1 0.0 0.0011 18.7 0.0 3.4 3 0 0 3 3 3 2 Retroviral aspartyl protease Rhamno_transf PF11316.8 GBG75832.1 - 0.0039 16.6 0.3 0.35 10.2 0.0 3.0 2 0 0 2 2 2 1 Putative rhamnosyl transferase Asp_protease PF09668.10 GBG75832.1 - 0.0057 16.5 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG75832.1 - 0.073 12.8 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Putative peptidase (DUF1758) SH3_16 PF18348.1 GBG75832.1 - 0.086 12.7 0.0 5 7.0 0.0 2.9 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain HAUS6_N PF14661.6 GBG75832.1 - 0.54 9.8 5.7 1 8.9 0.8 3.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.15 GBG75832.1 - 7.4 6.4 12.9 6 6.7 1.4 3.1 2 0 0 2 2 2 0 Septum formation initiator IL11 PF07400.11 GBG75833.1 - 0.032 13.9 0.1 0.032 13.9 0.1 1.8 2 0 0 2 2 2 0 Interleukin 11 CCDC106 PF15794.5 GBG75833.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF659 PF04937.15 GBG75834.1 - 4e-17 62.5 0.0 5.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Collagen PF01391.18 GBG75835.1 - 4 7.3 27.5 27 4.6 27.5 2.2 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) RVT_1 PF00078.27 GBG75836.1 - 0.0053 16.3 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Attractin PF08037.11 GBG75837.1 - 0.4 10.7 0.0 0.4 10.7 0.0 2.6 3 0 0 3 3 3 0 Attractin family DUF659 PF04937.15 GBG75838.1 - 6.9e-28 97.4 0.0 1.7e-27 96.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Endostatin PF06482.11 GBG75838.1 - 9.3 5.6 17.6 14 5.1 17.6 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin GRP PF07172.11 GBG75839.1 - 0.026 15.2 29.6 0.65 10.7 20.3 2.2 2 0 0 2 2 2 0 Glycine rich protein family DUF1682 PF07946.14 GBG75839.1 - 0.13 11.4 3.5 0.18 11.0 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TT_ORF2 PF02957.15 GBG75839.1 - 0.58 11.1 6.1 0.1 13.5 1.2 2.0 2 0 0 2 2 2 0 TT viral ORF2 DUF4710 PF15828.5 GBG75839.1 - 1.1 9.4 8.9 1.7 8.9 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) SelK_SelG PF10961.8 GBG75839.1 - 1.5 9.5 24.3 2.4 8.8 1.0 2.2 2 0 0 2 2 2 0 Selenoprotein SelK_SelG TMEM208_SND2 PF05620.11 GBG75839.1 - 5 6.9 5.0 7.3 6.3 5.0 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Ferlin_C PF16165.5 GBG75839.1 - 5.7 6.9 5.9 8.4 6.3 5.9 1.2 1 0 0 1 1 1 0 Ferlin C-terminus MREG PF15812.5 GBG75840.1 - 0.018 15.4 1.4 0.034 14.5 1.4 1.4 1 0 0 1 1 1 0 Melanoregulin DNA_topoisoIV PF00521.20 GBG75840.1 - 0.74 8.6 5.2 0.82 8.5 5.2 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A AAA_24 PF13479.6 GBG75841.1 - 1.2 8.8 10.3 0.1 12.3 4.0 1.9 1 1 0 2 2 2 0 AAA domain DUF659 PF04937.15 GBG75842.1 - 8.6e-25 87.4 1.4 8.9e-25 87.3 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG75843.1 - 1.5e-28 99.8 0.2 2.3e-28 99.2 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75843.1 - 3.1e-24 84.9 0.0 8e-24 83.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75843.1 - 1.1e-15 57.8 0.0 2.4e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG75843.1 - 0.0014 19.2 0.0 0.003 18.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG75843.1 - 0.0079 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG75843.1 - 0.012 16.2 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG75843.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DIRP PF06584.13 GBG75843.1 - 0.14 12.3 0.0 0.57 10.4 0.0 2.0 1 0 0 1 1 1 0 DIRP RVT_1 PF00078.27 GBG75844.1 - 2e-27 96.2 0.1 3.1e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG75844.1 - 0.0069 16.6 0.3 0.18 12.1 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG75845.1 - 2.8e-28 97.9 0.0 6.4e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75845.1 - 8.7e-28 96.7 0.1 2.5e-27 95.2 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75845.1 - 5.2e-14 52.5 0.0 1.4e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG75845.1 - 6e-11 42.3 0.2 3.7e-10 39.8 0.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG75845.1 - 1.3e-07 31.5 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75845.1 - 5e-05 23.1 0.0 9.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG75845.1 - 5.2e-05 23.8 0.0 0.00023 21.8 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG75845.1 - 5.2e-05 23.7 0.0 0.00018 22.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease CCD48 PF15799.5 GBG75845.1 - 0.038 12.3 1.4 0.062 11.6 1.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Rhamno_transf PF11316.8 GBG75845.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase Chromo PF00385.24 GBG75845.1 - 0.14 12.1 0.1 0.56 10.2 0.0 2.2 2 0 0 2 2 1 0 Chromo (CHRromatin Organisation MOdifier) domain HALZ PF02183.18 GBG75845.1 - 2.4 8.4 6.4 0.84 9.9 1.9 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 GBG75845.1 - 6.7 6.9 7.9 0.98 9.5 3.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper RVT_1 PF00078.27 GBG75846.1 - 2.2e-32 112.4 0.0 3.4e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG75846.1 - 0.01 16.4 0.0 0.033 14.8 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG75846.1 - 0.011 16.3 0.6 0.038 14.6 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Miga PF10265.9 GBG75846.1 - 0.099 11.6 2.9 0.13 11.2 2.9 1.1 1 0 0 1 1 1 0 Mitoguardin RVP_2 PF08284.11 GBG75846.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Rrn6 PF10214.9 GBG75846.1 - 8.4 4.8 14.1 13 4.2 14.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF659 PF04937.15 GBG75847.1 - 1.9e-28 99.2 0.0 3.5e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SseC PF04888.12 GBG75847.1 - 0.0062 16.2 5.8 0.01 15.5 5.8 1.3 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Retrotrans_gag PF03732.17 GBG75848.1 - 0.012 15.9 0.0 0.058 13.7 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG75848.1 - 0.046 14.3 0.1 0.1 13.2 0.1 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG75848.1 - 0.055 13.3 0.1 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 GBG75848.1 - 0.096 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG75849.1 - 1.4e-31 108.5 0.0 2.8e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75849.1 - 2.3e-28 98.6 0.1 4.6e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75849.1 - 1.1e-17 63.9 1.8 1.6e-17 63.3 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG75849.1 - 2.4e-15 56.7 0.1 8.5e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG75849.1 - 0.024 14.9 0.0 0.075 13.3 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG75851.1 - 9.6e-08 31.8 2.2 2e-07 30.8 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG75851.1 - 0.032 14.1 1.8 0.066 13.1 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-Mss51 PF13824.6 GBG75851.1 - 0.15 12.1 1.7 0.27 11.4 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 KfrA_N PF11740.8 GBG75852.1 - 0.2 12.3 6.3 4.5 8.0 6.0 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF390 PF04094.14 GBG75852.1 - 0.25 9.6 10.0 0.38 9.0 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF1682 PF07946.14 GBG75852.1 - 4.4 6.4 13.7 7.2 5.7 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AFT PF08731.11 GBG75852.1 - 7.9 6.9 7.5 1e+02 3.3 7.5 2.6 1 1 0 1 1 1 0 Transcription factor AFT RcbX PF02341.15 GBG75854.1 - 1.7e-19 70.2 1.3 2.3e-19 69.7 1.3 1.1 1 0 0 1 1 1 1 RbcX protein DUF1460 PF07313.12 GBG75854.1 - 0.068 12.6 0.2 0.12 11.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1460) gag-asp_proteas PF13975.6 GBG75855.1 - 0.00097 19.7 0.0 0.0027 18.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG75855.1 - 0.0034 17.6 0.6 0.013 15.7 0.3 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein RVP PF00077.20 GBG75855.1 - 0.004 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG75855.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG75855.1 - 0.043 14.4 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease CDC45 PF02724.14 GBG75856.1 - 0.39 8.9 6.0 0.73 8.0 6.0 1.3 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG75857.1 - 1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG75857.1 - 0.042 14.4 0.4 0.19 12.3 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75857.1 - 0.11 13.2 0.0 0.46 11.2 0.0 2.1 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG75858.1 - 1.5e-12 47.6 0.0 2.3e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Med26_C PF15693.5 GBG75859.1 - 1.2 9.3 8.8 0.68 10.1 4.7 2.5 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal ORC6 PF05460.13 GBG75860.1 - 0.24 10.6 7.2 0.34 10.2 7.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ribosomal_60s PF00428.19 GBG75860.1 - 1.1 9.9 0.0 1.1 9.9 0.0 4.3 2 1 0 2 2 2 0 60s Acidic ribosomal protein CDC45 PF02724.14 GBG75860.1 - 1.2 7.4 21.8 1.6 6.9 21.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Yae1_N PF09811.9 GBG75861.1 - 0.012 15.3 15.7 1.3 8.8 0.0 8.2 9 1 1 10 10 10 0 Essential protein Yae1, N terminal Yae1_N PF09811.9 GBG75862.1 - 2.5e-08 33.5 4.2 6.4 6.6 0.0 9.9 12 1 1 13 13 13 2 Essential protein Yae1, N terminal DUF2717 PF10911.8 GBG75862.1 - 0.056 13.2 0.4 37 4.1 0.0 5.2 4 2 1 6 6 6 0 Protein of unknown function (DUF2717) Yae1_N PF09811.9 GBG75863.1 - 3.5e-08 33.0 7.3 0.26 11.0 0.0 6.7 5 3 2 7 7 7 6 Essential protein Yae1, N terminal Yae1_N PF09811.9 GBG75864.1 - 4.5e-07 29.5 11.7 3.5 7.4 1.8 9.3 5 3 2 7 7 7 3 Essential protein Yae1, N terminal Bactofilin PF04519.13 GBG75864.1 - 0.33 11.3 1.1 3.5 8.0 0.0 3.3 3 2 0 3 3 3 0 Polymer-forming cytoskeletal Ribosomal_L22 PF00237.19 GBG75866.1 - 1.7e-08 34.7 0.2 2.7e-08 34.0 0.2 1.6 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e DUF3987 PF13148.6 GBG75866.1 - 6.3e-05 22.2 0.1 0.0025 16.9 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3987) DUF3987 PF13148.6 GBG75867.1 - 1.2e-12 47.6 0.3 4.8e-07 29.1 0.1 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF3987) Ribosomal_L22 PF00237.19 GBG75867.1 - 2.7e-08 34.0 0.1 5.1e-08 33.1 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e UPF0020 PF01170.18 GBG75869.1 - 5.2e-08 32.8 0.1 0.00016 21.4 0.2 3.1 2 1 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 GBG75869.1 - 0.00056 20.6 0.0 0.015 16.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG75869.1 - 0.0032 17.3 0.0 0.0087 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 GBG75869.1 - 0.0033 17.2 0.0 0.0053 16.5 0.0 1.2 1 0 0 1 1 1 1 DNA methylase CMAS PF02353.20 GBG75869.1 - 0.0069 15.7 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 GBG75869.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SRF-TF PF00319.18 GBG75870.1 - 1.4e-24 85.3 0.2 2.2e-24 84.6 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Cwf_Cwc_15 PF04889.12 GBG75870.1 - 0.012 15.4 2.6 0.019 14.7 2.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HJURP_C PF12347.8 GBG75870.1 - 0.02 14.9 0.3 0.047 13.7 0.0 1.7 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat PPP4R2 PF09184.11 GBG75870.1 - 0.16 11.5 2.6 0.2 11.2 2.6 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GBG75870.1 - 0.25 9.5 7.3 0.33 9.1 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 GBG75870.1 - 1.5 7.9 2.8 2.7 7.1 2.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SpoU_methylase PF00588.19 GBG75871.1 - 1.1e-26 93.7 0.3 2.6e-26 92.5 0.0 1.8 2 0 0 2 2 2 1 SpoU rRNA Methylase family DUF1192 PF06698.11 GBG75871.1 - 0.024 14.7 1.5 0.024 14.7 1.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) RT_RNaseH_2 PF17919.1 GBG75872.1 - 5.6e-32 109.8 0.0 1.4e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75872.1 - 1.9e-31 109.3 0.1 3.6e-31 108.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75872.1 - 2.4e-27 95.3 0.0 7.1e-27 93.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75872.1 - 1.3e-14 54.0 0.0 3.2e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75872.1 - 2e-13 50.6 0.0 6e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain FtsK_4TM PF13491.6 GBG75872.1 - 0.19 11.4 0.1 0.33 10.6 0.1 1.2 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE MSP1_C PF07462.11 GBG75872.1 - 2.6 6.7 7.1 4.7 5.8 7.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-CCHC_4 PF14392.6 GBG75873.1 - 0.092 12.5 1.2 0.24 11.2 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG75873.1 - 9 6.6 7.1 0.65 10.2 1.1 2.4 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH PF17917.1 GBG75874.1 - 2e-48 163.0 0.1 4.1e-23 81.7 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75874.1 - 9e-41 138.0 0.0 2e-20 72.7 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75874.1 - 1.7e-13 50.8 0.0 4.6e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG75874.1 - 3.1e-12 46.4 0.2 7e-12 45.3 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Jnk-SapK_ap_N PF09744.9 GBG75874.1 - 0.0022 18.2 8.0 0.0022 18.2 8.0 3.3 4 0 0 4 4 4 1 JNK_SAPK-associated protein-1 zf-H2C2 PF09337.10 GBG75874.1 - 0.11 12.7 0.4 0.22 11.8 0.4 1.5 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG75875.1 - 8e-24 83.9 0.1 2.9e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75875.1 - 7.8e-18 64.4 0.0 2.1e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75875.1 - 1.2e-13 51.3 0.0 3.2e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG75875.1 - 2.6e-12 46.7 0.2 5.1e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Jnk-SapK_ap_N PF09744.9 GBG75875.1 - 0.0016 18.7 8.0 0.0016 18.7 8.0 3.4 4 0 0 4 4 4 1 JNK_SAPK-associated protein-1 zf-H2C2 PF09337.10 GBG75875.1 - 0.082 13.1 0.4 0.16 12.2 0.4 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Aminotran_5 PF00266.19 GBG75877.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V ABATE PF07336.11 GBG75877.1 - 2.6 8.7 7.9 0.33 11.6 0.7 3.3 4 0 0 4 4 4 0 Putative stress-induced transcription regulator Mut7-C PF01927.16 GBG75879.1 - 0.00037 20.6 0.2 0.0011 19.1 0.2 1.8 1 0 0 1 1 1 1 Mut7-C RNAse domain Baculo_p24 PF05073.12 GBG75879.1 - 0.0073 16.1 0.1 0.0073 16.1 0.1 2.2 3 0 0 3 3 3 1 Baculovirus P24 capsid protein NMD3 PF04981.13 GBG75879.1 - 0.015 14.8 1.8 0.067 12.7 0.1 2.4 2 0 0 2 2 2 0 NMD3 family DUF3194 PF11419.8 GBG75879.1 - 0.024 15.0 1.4 0.06 13.7 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3194) Kelch_5 PF13854.6 GBG75880.1 - 3.8e-15 55.5 2.7 0.024 14.7 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 GBG75880.1 - 2.2e-12 46.9 9.6 1.5e-05 25.2 0.1 7.5 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 GBG75880.1 - 1.6e-10 40.8 21.5 0.00023 21.1 0.1 8.1 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GBG75880.1 - 5.3e-08 32.9 5.8 0.089 13.1 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 GBG75880.1 - 2e-06 27.2 4.2 0.55 9.9 0.0 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 GBG75880.1 - 0.0016 18.4 7.9 6 7.0 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Bap31_Bap29_C PF18035.1 GBG75880.1 - 4.8 7.3 15.3 22 5.2 5.8 3.9 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Kelch_5 PF13854.6 GBG75881.1 - 3.5e-15 55.6 2.7 0.023 14.7 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 GBG75881.1 - 2e-12 47.1 9.6 1.4e-05 25.2 0.1 7.5 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 GBG75881.1 - 1.5e-10 40.9 21.6 0.00023 21.1 0.1 8.1 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GBG75881.1 - 4.8e-08 33.0 5.8 0.088 13.1 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 GBG75881.1 - 1.9e-06 27.4 4.2 0.54 9.9 0.0 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 GBG75881.1 - 0.0015 18.5 7.9 5.9 7.0 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Bap31_Bap29_C PF18035.1 GBG75881.1 - 4.4 7.4 15.3 21 5.2 5.8 3.9 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Peptidase_M23 PF01551.22 GBG75882.1 - 2.2e-27 95.1 2.4 2.6e-27 94.9 0.7 2.1 2 0 0 2 2 2 1 Peptidase family M23 RVT_1 PF00078.27 GBG75882.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Biotin_lipoyl_2 PF13533.6 GBG75882.1 - 0.0023 17.7 0.1 0.0062 16.3 0.1 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like Asp_protease_2 PF13650.6 GBG75882.1 - 0.066 13.9 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG75882.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Nsp1_C PF05064.13 GBG75884.1 - 1.9e-19 69.5 4.0 1.9e-19 69.5 4.0 1.6 1 1 1 2 2 2 1 Nsp1-like C-terminal region Unstab_antitox PF09720.10 GBG75884.1 - 0.042 13.9 0.9 0.1 12.7 0.9 1.6 1 0 0 1 1 1 0 Putative addiction module component Sec34 PF04136.15 GBG75884.1 - 0.049 13.5 3.0 0.062 13.2 2.3 1.4 1 1 0 1 1 1 0 Sec34-like family UPF0242 PF06785.11 GBG75884.1 - 5.3 7.1 8.7 7.6 6.6 8.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 GBG75884.1 - 9.8 6.7 15.7 19 5.8 15.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region F-box PF00646.33 GBG75885.1 - 7.2e-05 22.6 0.3 7.2e-05 22.6 0.3 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 GBG75885.1 - 0.0023 17.8 0.8 0.0023 17.8 0.8 2.5 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 GBG75885.1 - 0.0057 16.6 2.9 6.2 7.2 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 GBG75885.1 - 0.0091 16.4 0.2 3.6 8.1 0.0 3.5 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) Nop14 PF04147.12 GBG75885.1 - 5.9 5.0 8.3 10 4.2 8.3 1.3 1 0 0 1 1 1 0 Nop14-like family SPOUT_MTase PF02590.17 GBG75887.1 - 3.6e-42 143.9 2.5 1.1e-41 142.4 0.0 2.8 3 1 0 3 3 3 1 Predicted SPOUT methyltransferase CENP-B_dimeris PF09026.10 GBG75887.1 - 0.0028 18.0 6.9 0.0028 18.0 6.9 2.4 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Hint PF01079.20 GBG75887.1 - 0.073 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Hint module tRNA_synt_1c_R2 PF04557.15 GBG75887.1 - 3.2 8.8 9.5 8 7.5 1.5 2.8 3 0 0 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 FAM176 PF14851.6 GBG75887.1 - 4.5 6.9 15.8 6.4 6.4 4.9 2.7 2 0 0 2 2 2 0 FAM176 family Ribosomal_L4 PF00573.22 GBG75889.1 - 7.2e-42 143.2 0.1 7.2e-42 143.2 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 GBG75889.1 - 3.2e-26 91.2 4.9 3.2e-26 91.2 4.9 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DUF3008 PF11450.8 GBG75889.1 - 0.0054 16.9 0.5 0.014 15.6 0.5 1.8 1 0 0 1 1 1 1 Protein of unknwon function (DUF3008) FAM47 PF14642.6 GBG75889.1 - 0.6 9.6 3.3 0.6 9.6 0.6 2.0 2 0 0 2 2 2 0 FAM47 family CEND1 PF15677.5 GBG75890.1 - 5.6 7.5 8.8 5.5 7.5 1.8 3.3 3 0 0 3 3 3 0 Cell cycle exit and neuronal differentiation protein 1 Sporozoite_P67 PF05642.11 GBG75891.1 - 0.39 8.7 10.4 0.44 8.6 10.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 GBG75891.1 - 1.8 6.6 12.5 2.1 6.5 12.5 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG75891.1 - 3.5 6.3 4.9 3.9 6.1 4.9 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG75891.1 - 3.7 5.7 17.3 4.3 5.5 17.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 GBG75891.1 - 3.9 7.2 16.3 4.9 6.9 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) EIF4E-T PF10477.9 GBG75891.1 - 5.6 5.7 13.6 6.2 5.5 13.6 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Paf1 PF03985.13 GBG75891.1 - 6.5 5.6 20.6 7.7 5.4 20.6 1.0 1 0 0 1 1 1 0 Paf1 Popeye PF04831.13 GBG75892.1 - 1.9e-20 73.4 0.1 3.2e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 GBG75892.1 - 2.9e-11 43.3 0.0 7.2e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DIL PF01843.19 GBG75892.1 - 0.064 13.5 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 DIL domain AMP-binding PF00501.28 GBG75893.1 - 7.7e-56 189.5 0.0 1.1e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Carboxyl_trans PF01039.22 GBG75894.1 - 4.5e-158 526.9 0.0 6.2e-158 526.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 GBG75894.1 - 3.1e-142 475.4 0.0 5.9e-142 474.4 0.0 1.4 1 1 0 1 1 1 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 GBG75894.1 - 1.4e-46 158.6 0.0 2.5e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GBG75894.1 - 2.7e-31 108.4 0.0 6.6e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GBG75894.1 - 2.9e-20 72.4 0.0 8.4e-20 70.9 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_3 PF02655.14 GBG75894.1 - 1.6e-09 38.0 0.0 3.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.22 GBG75894.1 - 9.4e-08 31.8 0.0 2.5e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 GBG75894.1 - 3.1e-05 23.6 0.0 0.00013 21.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GBG75894.1 - 0.0017 18.0 0.0 0.006 16.1 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus RVT_1 PF00078.27 GBG75896.1 - 2.6e-30 105.6 0.1 4.9e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG75896.1 - 5e-19 68.2 0.0 1.1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75896.1 - 6.9e-07 29.5 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LOH1CR12 PF10158.9 GBG75896.1 - 0.082 12.9 0.4 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 Tumour suppressor protein Spectrin PF00435.21 GBG75896.1 - 0.41 11.2 6.5 0.11 13.0 0.9 2.8 3 0 0 3 3 3 0 Spectrin repeat zf-CCHC PF00098.23 GBG75897.1 - 3e-08 33.4 2.9 7.1e-08 32.2 2.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG75897.1 - 0.01 15.6 2.2 0.026 14.2 2.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Prok-RING_1 PF14446.6 GBG75897.1 - 0.12 12.3 0.6 0.28 11.1 0.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Astro_capsid_p PF12226.8 GBG75897.1 - 0.37 9.9 5.8 0.66 9.1 5.8 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-CCHC_2 PF13696.6 GBG75897.1 - 5.9 6.8 6.0 4.6 7.2 2.5 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF1980 PF09323.10 GBG75897.1 - 6.9 6.5 4.8 17 5.3 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Alanine_zipper PF11839.8 GBG75898.1 - 0.095 13.1 19.9 0.044 14.1 17.3 1.8 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Remorin_C PF03763.13 GBG75898.1 - 0.66 9.9 33.1 0.075 12.9 18.2 2.6 1 1 1 2 2 2 0 Remorin, C-terminal region Presenilin PF01080.17 GBG75898.1 - 6.7 5.4 8.4 9.6 4.8 8.4 1.1 1 0 0 1 1 1 0 Presenilin Pro_racemase PF05544.11 GBG75900.1 - 0.0056 15.8 1.3 0.29 10.1 0.1 2.6 2 1 0 3 3 3 2 Proline racemase Utp14 PF04615.13 GBG75900.1 - 5 5.6 22.8 6.2 5.3 22.8 1.0 1 0 0 1 1 1 0 Utp14 protein V_ATPase_I PF01496.19 GBG75900.1 - 10 3.9 16.8 0.18 9.7 0.1 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family COBRA PF04833.15 GBG75902.1 - 2.7e-19 69.7 4.4 5.1e-18 65.5 4.4 2.6 1 1 0 1 1 1 1 COBRA-like protein SDA1 PF05285.12 GBG75903.1 - 0.28 10.5 17.5 0.36 10.2 17.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG75903.1 - 0.73 8.1 13.0 0.92 7.7 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG75903.1 - 0.74 9.1 18.9 1 8.6 18.9 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG75903.1 - 1.6 6.8 19.7 2.2 6.4 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 GBG75903.1 - 3.3 6.8 8.9 4.5 6.3 8.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PPP4R2 PF09184.11 GBG75903.1 - 3.7 7.1 16.2 5.5 6.5 16.2 1.3 1 0 0 1 1 1 0 PPP4R2 DUF913 PF06025.12 GBG75903.1 - 4.6 6.1 4.5 6.4 5.6 4.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Na_trans_assoc PF06512.13 GBG75904.1 - 2.4 8.4 10.2 4.6 7.5 10.2 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG75904.1 - 3.2 7.1 16.9 0.082 12.3 10.0 1.8 2 0 0 2 2 2 0 SDA1 SIR4_SID PF16991.5 GBG75904.1 - 3.2 7.8 5.6 6.1 6.9 5.6 1.4 1 0 0 1 1 1 0 Sir4 SID domain PPP4R2 PF09184.11 GBG75904.1 - 3.3 7.2 9.3 6.3 6.3 9.3 1.4 1 0 0 1 1 1 0 PPP4R2 Exo_endo_phos PF03372.23 GBG75905.1 - 2.1e-13 50.3 0.0 5.7e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG75905.1 - 4.5e-06 26.5 0.1 8.7e-05 22.4 0.0 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG75906.1 - 0.01 15.6 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF2058 PF09831.9 GBG75907.1 - 0.3 11.2 13.5 0.61 10.2 13.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) V_ATPase_I PF01496.19 GBG75907.1 - 3.6 5.4 9.7 4.7 5.0 9.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phlebovirus_NSM PF07246.11 GBG75907.1 - 9.6 5.5 15.5 1.6 8.0 11.3 1.8 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Pkinase_Tyr PF07714.17 GBG75908.1 - 2.1e-13 50.2 0.8 1.1e-06 28.2 0.1 3.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG75908.1 - 1.2e-10 41.2 0.2 1.4e-09 37.7 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Cadherin_C_2 PF16492.5 GBG75908.1 - 0.12 13.2 0.2 0.34 11.7 0.2 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Mpp10 PF04006.12 GBG75908.1 - 2.1 6.7 44.2 3.2 6.1 44.2 1.2 1 0 0 1 1 1 0 Mpp10 protein Spore_coat_CotO PF14153.6 GBG75908.1 - 6.4 6.7 32.8 12 5.8 32.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO BTB PF00651.31 GBG75909.1 - 1.5e-14 54.1 0.0 3.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 GBG75909.1 - 0.0053 16.9 0.0 0.019 15.1 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Lin-8 PF03353.15 GBG75911.1 - 4.5 6.7 12.8 0.8 9.2 9.1 1.5 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist RT_RNaseH PF17917.1 GBG75912.1 - 5e-23 81.4 0.0 4.8e-21 75.0 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75912.1 - 5.2e-20 71.3 0.0 2.4e-19 69.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75912.1 - 2.1e-15 56.5 0.4 5.7e-15 55.2 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG75912.1 - 7.8e-07 28.8 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG75912.1 - 3.2e-06 27.3 0.0 1.3e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG75912.1 - 0.0011 19.2 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG75913.1 - 3.5e-27 94.4 0.3 1.8e-26 92.1 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75913.1 - 1e-21 77.2 0.2 3.5e-21 75.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75913.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3138 PF11336.8 GBG75913.1 - 1.1 7.9 3.1 1.8 7.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DDE_Tnp_4 PF13359.6 GBG75915.1 - 2.1e-19 69.8 0.0 5.8e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75915.1 - 0.0043 16.7 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Aldo_ket_red PF00248.21 GBG75916.1 - 2.2e-76 256.9 0.0 2.6e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA_lig_kinase PF08303.11 GBG75917.1 - 0.011 15.9 0.5 0.2 11.7 0.7 2.5 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF2812 PF11193.8 GBG75917.1 - 0.062 13.5 0.1 0.24 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) Aldo_ket_red PF00248.21 GBG75918.1 - 5.1e-75 252.4 0.0 6.5e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MannoseP_isomer PF01050.18 GBG75918.1 - 0.12 12.3 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase DDE_Tnp_4 PF13359.6 GBG75919.1 - 6.6e-30 103.9 0.0 1.1e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75919.1 - 1e-14 54.7 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG75919.1 - 0.052 13.2 0.2 2.2 7.9 0.1 2.5 2 1 0 2 2 2 0 Transposase DDE domain Ribosomal_L30_N PF08079.12 GBG75921.1 - 1.1e-22 80.0 8.3 1.1e-22 80.0 8.3 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 GBG75921.1 - 7.1e-07 29.0 0.2 1.9e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Aldo_ket_red PF00248.21 GBG75922.1 - 1.1e-76 257.9 0.0 1.2e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 GBG75923.1 - 8.5e-74 248.4 0.0 1.1e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RT_RNaseH PF17917.1 GBG75924.1 - 1.8e-22 79.6 0.0 4.2e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75924.1 - 5e-21 74.6 0.0 1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75924.1 - 4.2e-14 52.4 0.1 1.4e-13 50.7 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG75924.1 - 3.7e-12 46.5 0.0 1.4e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Ribosomal_60s PF00428.19 GBG75924.1 - 0.11 13.1 10.9 1.1 9.9 10.9 2.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Dapper PF15268.6 GBG75925.1 - 0.92 8.3 16.5 1.2 8.0 16.5 1.1 1 0 0 1 1 1 0 Dapper Utp14 PF04615.13 GBG75925.1 - 5 5.6 31.9 5.9 5.3 31.9 1.0 1 0 0 1 1 1 0 Utp14 protein Nop14 PF04147.12 GBG75927.1 - 0.91 7.7 5.5 1.2 7.3 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family Cnd2 PF05786.14 GBG75927.1 - 1.4 7.5 8.1 2.1 6.9 8.1 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 COPI_C PF06957.11 GBG75927.1 - 2.5 6.8 6.8 3.6 6.2 6.8 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Aldo_ket_red PF00248.21 GBG75928.1 - 3.3e-70 236.6 0.0 3.9e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ubiq_cyt_C_chap PF03981.12 GBG75928.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Ish1 PF10281.9 GBG75929.1 - 0.00082 19.6 0.4 0.0028 17.9 0.0 2.2 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein Slx4 PF09494.10 GBG75929.1 - 0.027 14.4 0.1 0.075 13.0 0.1 1.8 1 0 0 1 1 1 0 Slx4 endonuclease CHZ PF09649.10 GBG75930.1 - 0.056 12.9 0.3 0.21 11.1 0.3 2.0 1 0 0 1 1 1 0 Histone chaperone domain CHZ FliJ PF02050.16 GBG75930.1 - 6.6 7.0 9.1 4.3 7.6 2.3 2.8 3 1 0 3 3 3 0 Flagellar FliJ protein MMR_HSR1 PF01926.23 GBG75931.1 - 2.1e-07 31.0 0.1 3.5e-06 27.1 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 GBG75931.1 - 1.4e-06 27.8 0.0 0.0039 16.5 0.0 2.5 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 GBG75931.1 - 3.4e-05 23.8 0.0 0.0001 22.3 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 GBG75931.1 - 0.00034 20.4 0.0 0.17 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 GBG75931.1 - 0.00035 20.0 0.1 0.001 18.4 0.1 1.8 1 1 0 1 1 1 1 Septin AAA_29 PF13555.6 GBG75931.1 - 0.00094 18.9 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG75931.1 - 0.0012 19.3 0.0 0.005 17.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 GBG75931.1 - 0.0026 17.0 0.5 0.016 14.4 0.2 2.6 2 1 0 2 2 2 1 G-protein alpha subunit MCM PF00493.23 GBG75931.1 - 0.0061 15.7 0.0 0.025 13.7 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain AAA_7 PF12775.7 GBG75931.1 - 0.0093 15.5 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 GBG75931.1 - 0.01 15.0 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein IIGP PF05049.13 GBG75931.1 - 0.013 14.6 0.0 0.041 12.9 0.0 1.8 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 GBG75931.1 - 0.021 15.3 0.0 0.11 13.0 0.0 2.2 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 GBG75931.1 - 0.026 14.5 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 GBG75931.1 - 0.036 13.6 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GBG75931.1 - 0.04 14.2 0.0 0.56 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 GBG75931.1 - 0.042 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 GBG75931.1 - 0.072 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 GBG75931.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Luciferase_N PF05295.11 GBG75931.1 - 0.13 12.3 0.1 6.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Luciferase/LBP N-terminal domain Roc PF08477.13 GBG75931.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GBG75931.1 - 0.42 10.7 2.9 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Dynamin family C6_DPF PF10170.9 GBG75931.1 - 0.78 10.2 5.8 0.19 12.1 0.3 2.4 2 0 0 2 2 2 0 Cysteine-rich domain AAA_23 PF13476.6 GBG75931.1 - 6.5 7.2 11.8 40 4.6 8.1 3.3 2 1 0 2 2 2 0 AAA domain Prefoldin PF02996.17 GBG75932.1 - 0.02 14.8 2.1 0.62 10.0 0.1 3.3 2 2 0 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 GBG75932.1 - 0.03 14.7 3.7 0.23 11.9 1.2 2.8 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) betaPIX_CC PF16523.5 GBG75932.1 - 0.071 12.9 0.1 0.071 12.9 0.1 3.0 4 1 0 4 4 4 0 betaPIX coiled coil Flagellin_N PF00669.20 GBG75932.1 - 0.14 12.2 1.6 0.21 11.7 0.3 1.8 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Spc7 PF08317.11 GBG75932.1 - 0.15 10.9 16.3 0.42 9.4 7.3 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein CorA PF01544.18 GBG75932.1 - 0.15 11.3 3.6 0.11 11.8 1.9 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Rx_N PF18052.1 GBG75932.1 - 0.7 10.2 8.9 1.4 9.2 0.4 3.7 2 2 2 4 4 4 0 Rx N-terminal domain bZIP_1 PF00170.21 GBG75932.1 - 0.72 10.0 6.3 0.45 10.7 0.5 3.1 2 1 1 3 3 3 0 bZIP transcription factor Phage_GPO PF05929.11 GBG75932.1 - 0.83 9.2 6.4 0.1 12.2 1.8 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Filament PF00038.21 GBG75932.1 - 1 8.8 11.8 0.27 10.8 7.1 2.2 2 1 0 2 2 2 0 Intermediate filament protein HALZ PF02183.18 GBG75932.1 - 2.1 8.7 16.6 0.37 11.0 0.5 4.7 4 2 0 4 4 4 0 Homeobox associated leucine zipper DivIC PF04977.15 GBG75932.1 - 3.4 7.5 7.2 3 7.7 0.7 3.3 2 1 1 3 3 3 0 Septum formation initiator Cep57_CLD_2 PF14197.6 GBG75932.1 - 4.2 7.5 15.4 13 6.0 5.5 3.6 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 GBG75932.1 - 4.7 7.7 14.1 0.87 10.1 0.6 3.6 3 1 0 3 3 3 0 Cell division protein ZapB Cnn_1N PF07989.11 GBG75932.1 - 5.4 7.2 8.0 1.3 9.2 0.3 3.3 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 CCDC-167 PF15188.6 GBG75932.1 - 6.3 7.2 8.7 79 3.7 5.5 3.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 CENP-F_leu_zip PF10473.9 GBG75932.1 - 8.8 6.4 16.5 0.59 10.2 6.1 3.3 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Retrotrans_gag PF03732.17 GBG75933.1 - 0.0038 17.5 0.1 0.0038 17.5 0.1 3.6 3 1 1 4 4 4 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG75933.1 - 0.016 15.0 1.1 0.062 13.1 1.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG75933.1 - 0.041 13.2 7.5 0.074 12.4 7.5 1.4 1 0 0 1 1 1 0 FAM76 protein eIF3_subunit PF08597.10 GBG75933.1 - 0.18 11.7 8.2 0.28 11.0 8.2 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF5401 PF17380.2 GBG75933.1 - 0.23 9.5 8.9 0.38 8.8 8.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF3573 PF12097.8 GBG75933.1 - 0.27 10.0 0.5 0.45 9.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) APG6_N PF17675.1 GBG75933.1 - 7.9 7.0 23.0 0.55 10.8 1.6 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 GBG75933.1 - 9.5 6.3 18.5 2.9e+02 1.4 18.5 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Retrotrans_gag PF03732.17 GBG75934.1 - 0.02 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG75934.1 - 0.061 13.4 3.1 0.1 12.7 3.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG75935.1 - 1.1e-11 44.9 0.0 1.7e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) YL1 PF05764.13 GBG75935.1 - 0.00047 20.4 3.7 0.001 19.3 3.7 1.5 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 GBG75935.1 - 0.071 11.4 4.3 0.096 11.0 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG75935.1 - 0.4 10.4 5.5 0.86 9.3 5.5 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 GBG75935.1 - 3.2 8.2 6.4 12 6.3 6.4 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HSP70 PF00012.20 GBG75937.1 - 1.6e-140 469.2 0.0 2e-140 468.8 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG75937.1 - 3e-05 23.0 0.0 0.0094 14.8 0.1 3.0 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 GBG75937.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Raco_middle PF17651.1 GBG75937.1 - 0.19 11.4 0.0 0.85 9.3 0.0 2.0 2 0 0 2 2 2 0 RACo middle region HSP70 PF00012.20 GBG75939.1 - 1.4e-149 499.1 0.0 1.9e-149 498.7 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG75939.1 - 1.6e-09 37.1 0.0 1.8e-08 33.6 0.0 2.4 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG75939.1 - 0.0043 16.8 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MutL PF13941.6 GBG75939.1 - 0.064 11.9 0.0 0.14 10.7 0.0 1.5 1 0 0 1 1 1 0 MutL protein FtsA PF14450.6 GBG75939.1 - 0.08 13.4 0.1 2.7 8.5 0.0 2.9 2 1 0 2 2 2 0 Cell division protein FtsA Raco_middle PF17651.1 GBG75939.1 - 0.17 11.6 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 RACo middle region HSP70 PF00012.20 GBG75940.1 - 1e-157 526.0 0.0 1.5e-91 307.5 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG75940.1 - 8.9e-08 31.3 0.0 3.6e-05 22.7 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GBG75940.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG75940.1 - 0.057 13.8 0.0 1.5 9.3 0.0 3.0 2 1 0 2 2 2 0 Cell division protein FtsA Methyltransf_12 PF08242.12 GBG75940.1 - 0.1 13.4 0.0 20 6.0 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain HSP70 PF00012.20 GBG75941.1 - 9.6e-146 486.4 0.0 1.2e-145 486.1 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG75941.1 - 1.5e-08 33.9 0.1 3.3e-07 29.4 0.0 2.7 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG75941.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG75941.1 - 0.022 15.1 0.2 1 9.8 0.0 3.1 2 1 0 2 2 2 0 Cell division protein FtsA MutL PF13941.6 GBG75941.1 - 0.11 11.0 0.0 0.26 9.9 0.0 1.5 1 0 0 1 1 1 0 MutL protein RT_RNaseH_2 PF17919.1 GBG75942.1 - 2.2e-29 101.4 0.0 4.5e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75942.1 - 1.5e-28 99.9 0.1 2.7e-28 99.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75942.1 - 2.2e-16 60.0 0.0 4.9e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75942.1 - 5.7e-16 58.8 0.0 1.3e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain eIF-1a PF01176.19 GBG75942.1 - 0.011 15.5 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 rve_3 PF13683.6 GBG75942.1 - 0.12 12.2 0.0 0.46 10.3 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain HSP70 PF00012.20 GBG75943.1 - 5.3e-138 460.9 0.0 2.3e-75 254.0 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG75943.1 - 1e-10 41.0 0.0 2.3e-06 26.7 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein FGGY_C PF02782.16 GBG75943.1 - 0.098 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG75943.1 - 0.17 12.3 0.4 1.9 8.9 0.0 2.9 3 1 0 3 3 3 0 Cell division protein FtsA Ldh_1_C PF02866.18 GBG75945.1 - 1e-35 123.2 0.0 1.5e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GBG75945.1 - 5.1e-12 46.1 0.1 8.3e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF3930 PF13067.6 GBG75945.1 - 0.15 12.3 1.2 7.1 7.0 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3930) Myb_DNA-bind_4 PF13837.6 GBG75946.1 - 1.4e-10 41.4 0.3 2.1e-10 40.8 0.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG75947.1 - 2.5e-19 69.2 0.0 1.1e-18 67.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75947.1 - 2.4e-11 43.9 0.0 1.5e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75947.1 - 5.2e-09 35.9 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG75947.1 - 1.9e-07 31.3 0.4 6e-07 29.7 0.1 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG75947.1 - 0.0045 17.2 0.3 0.033 14.5 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG75947.1 - 0.0056 16.8 1.6 0.012 15.8 1.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG75947.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 GBG75947.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain gag-asp_proteas PF13975.6 GBG75947.1 - 0.23 12.0 1.0 0.49 11.0 0.1 2.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease HSP70 PF00012.20 GBG75948.1 - 1e-135 453.3 0.0 3.9e-112 375.4 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG75948.1 - 2.5e-07 29.8 0.0 5.5e-06 25.4 0.0 2.6 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 GBG75948.1 - 2.8e-05 23.9 0.0 6.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG75948.1 - 0.022 15.1 0.6 0.93 9.9 0.0 2.8 2 1 0 2 2 2 0 Cell division protein FtsA Ribosomal_60s PF00428.19 GBG75948.1 - 7 7.3 7.1 11 6.7 5.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Integrase_H2C2 PF17921.1 GBG75949.1 - 8.6e-15 54.6 2.0 1.6e-14 53.7 0.7 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG75949.1 - 9.1e-14 51.6 0.4 3.7e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75949.1 - 3.6e-09 36.9 0.0 8.9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG75949.1 - 6.6e-08 32.5 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG75949.1 - 0.00027 21.1 0.2 0.00091 19.4 0.2 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG75949.1 - 0.00065 19.6 0.1 0.0017 18.2 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG75949.1 - 0.0061 16.3 0.6 0.019 14.7 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG75949.1 - 0.023 15.0 1.8 0.047 14.0 0.2 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2497 PF10691.9 GBG75949.1 - 0.059 13.8 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) HSP70 PF00012.20 GBG75950.1 - 1.1e-146 489.5 0.0 1.4e-146 489.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG75950.1 - 1.8e-08 33.6 0.3 1.1e-07 31.0 0.1 2.2 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG75950.1 - 0.00064 19.5 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Raco_middle PF17651.1 GBG75950.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 RACo middle region FtsA PF14450.6 GBG75950.1 - 0.15 12.5 1.4 2.7 8.5 0.1 2.8 2 2 0 2 2 2 0 Cell division protein FtsA Retrotrans_gag PF03732.17 GBG75951.1 - 0.0093 16.2 1.9 0.019 15.2 0.1 2.3 2 1 1 3 3 3 1 Retrotransposon gag protein Pro-rich PF15240.6 GBG75951.1 - 2.4 8.4 10.4 4.5 7.5 10.5 1.3 1 1 0 1 1 1 0 Proline-rich PapC_C PF13953.6 GBG75952.1 - 0.0039 17.0 29.8 4.8 7.1 1.4 8.5 3 2 7 10 10 10 4 PapC C-terminal domain Methyltransf_1N PF02870.15 GBG75952.1 - 0.39 11.6 9.5 40 5.1 0.2 5.5 1 1 5 6 6 6 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain SH3_19 PF18597.1 GBG75952.1 - 0.96 9.3 35.7 40 4.1 0.1 9.8 10 0 0 10 10 10 0 Myosin X N-terminal SH3 domain RTA1 PF04479.13 GBG75952.1 - 2.2 7.8 4.7 92 2.5 0.0 4.9 4 2 3 7 7 7 0 RTA1 like protein Integrase_H2C2 PF17921.1 GBG75953.1 - 7.9e-19 67.5 0.4 1.8e-18 66.4 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG75953.1 - 6.1e-14 52.2 0.1 1.4e-13 51.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75953.1 - 2.2e-07 30.8 0.0 4.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG75953.1 - 6.7e-06 26.3 0.1 2.3e-05 24.6 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG75953.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger HSP70 PF00012.20 GBG75954.1 - 4e-153 510.8 0.0 4.5e-153 510.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG75954.1 - 2e-08 33.4 0.1 1.4e-07 30.7 0.1 2.3 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG75954.1 - 0.0039 17.0 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG75954.1 - 0.045 14.2 1.3 3.5 8.1 0.0 3.0 2 2 0 2 2 2 0 Cell division protein FtsA Raco_middle PF17651.1 GBG75954.1 - 0.12 12.0 0.0 0.38 10.4 0.0 1.9 1 0 0 1 1 1 0 RACo middle region RVT_1 PF00078.27 GBG75955.1 - 3.3e-30 105.3 0.0 4.9e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG75955.1 - 2.2e-08 34.7 0.3 8.4e-08 32.8 0.1 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 GBG75955.1 - 0.00019 21.2 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GBG75955.1 - 0.017 14.6 0.0 0.051 13.1 0.0 1.8 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family HSP70 PF00012.20 GBG75956.1 - 1.6e-154 515.4 0.0 2e-154 515.1 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG75956.1 - 3e-09 36.1 0.2 1.4e-08 34.0 0.1 2.1 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG75956.1 - 0.0036 17.1 0.0 0.0083 15.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG75956.1 - 0.0082 16.6 0.5 1.2 9.6 0.0 3.1 2 2 0 2 2 2 1 Cell division protein FtsA Myb_DNA-bind_4 PF13837.6 GBG75957.1 - 9.7e-08 32.3 3.3 1.7e-07 31.5 3.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG75957.1 - 0.00041 20.5 2.3 0.0013 18.9 2.3 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG75957.1 - 0.0079 16.5 1.3 0.018 15.4 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG75957.1 - 0.033 14.4 0.8 0.089 13.1 0.7 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG75957.1 - 0.1 12.7 2.7 0.19 11.8 2.7 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain NTP_transf_9 PF04248.12 GBG75957.1 - 0.32 10.9 1.1 0.85 9.5 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF427) HSP70 PF00012.20 GBG75958.1 - 7.7e-148 493.3 0.0 9.5e-148 493.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG75958.1 - 6.3e-09 35.1 0.1 1e-07 31.1 0.1 2.4 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG75958.1 - 0.0053 16.5 0.1 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG75958.1 - 0.022 15.2 0.0 1.8 9.0 0.0 2.8 2 1 0 2 2 2 0 Cell division protein FtsA EspF PF04806.12 GBG75958.1 - 0.057 13.8 0.1 0.16 12.4 0.1 1.8 1 0 0 1 1 1 0 EspF protein repeat Phage_TAC_11 PF11836.8 GBG75958.1 - 0.13 12.4 0.1 1.3 9.1 0.0 2.4 1 1 1 2 2 2 0 Phage tail tube protein, GTA-gp10 HSP70 PF00012.20 GBG75959.1 - 7.7e-152 506.5 0.0 9e-152 506.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG75959.1 - 1e-07 31.1 0.3 2.4e-06 26.6 0.1 2.6 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 GBG75959.1 - 0.00039 20.2 0.0 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG75959.1 - 0.0012 19.2 1.1 0.83 10.1 0.0 3.5 2 1 0 2 2 2 2 Cell division protein FtsA Raco_middle PF17651.1 GBG75959.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 RACo middle region HSP70 PF00012.20 GBG75960.1 - 2.8e-135 451.9 0.0 7.4e-135 450.5 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG75960.1 - 1.4e-08 33.9 0.1 3.3e-06 26.2 0.1 3.1 3 1 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GBG75960.1 - 0.0036 17.0 0.3 0.0085 15.8 0.3 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Cornifin PF02389.15 GBG75960.1 - 0.0093 16.2 0.5 0.0093 16.2 0.5 1.7 2 0 0 2 2 2 1 Cornifin (SPRR) family DnaJ_CXXCXGXG PF00684.19 GBG75961.1 - 0.0077 16.6 17.4 0.059 13.7 16.2 2.7 1 1 1 2 2 2 2 DnaJ central domain MRC1 PF09444.10 GBG75961.1 - 0.03 14.8 2.7 0.043 14.3 2.7 1.2 1 0 0 1 1 1 0 MRC1-like domain DUF5351 PF17302.2 GBG75961.1 - 5.7 7.2 22.8 12 6.2 10.6 3.9 2 2 0 2 2 2 0 Family of unknown function (DUF5351) SWIRM-assoc_2 PF16496.5 GBG75962.1 - 3.4 6.5 8.1 3.3 6.5 3.7 2.1 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal RT_RNaseH_2 PF17919.1 GBG75963.1 - 1.1e-29 102.3 0.0 2.1e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75963.1 - 7.3e-28 96.9 0.0 1.3e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75963.1 - 2.3e-18 66.5 0.0 4e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG75963.1 - 0.0037 17.0 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) DUF659 PF04937.15 GBG75964.1 - 8.1e-15 55.0 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG75964.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region TIR_3 PF18567.1 GBG75964.1 - 0.17 11.9 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain RVT_1 PF00078.27 GBG75965.1 - 2e-32 112.5 0.3 3.4e-32 111.8 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2950 PF11453.8 GBG75965.1 - 0.61 9.2 8.5 1 8.5 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) TssO PF17561.2 GBG75965.1 - 2.9 8.0 6.3 9 6.4 6.3 1.8 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF3629 PF12302.8 GBG75965.1 - 3.3 7.1 8.3 7 6.0 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) PA26 PF04636.13 GBG75965.1 - 7.3 5.4 14.2 6.5 5.6 13.1 1.4 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) rve PF00665.26 GBG75966.1 - 2.6e-14 53.4 0.1 5.4e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG75966.1 - 0.12 12.0 0.3 0.5 10.0 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG75967.1 - 3.4e-28 98.7 0.0 6.6e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG75967.1 - 1.6e-05 25.1 0.0 4.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4407 PF14362.6 GBG75967.1 - 0.12 11.7 12.2 0.31 10.4 12.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 GBG75967.1 - 7.3 6.5 10.1 1.6 8.6 6.3 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase_Tyr PF07714.17 GBG75968.1 - 6e-38 130.6 0.0 1.3e-37 129.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG75968.1 - 2.9e-36 125.2 0.0 4e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG75968.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG75968.1 - 0.17 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Myb_DNA-bind_4 PF13837.6 GBG75969.1 - 3.6e-11 43.3 2.7 5.5e-11 42.7 2.7 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG75969.1 - 0.0063 16.7 0.7 0.013 15.7 0.7 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG75969.1 - 0.022 15.0 0.5 0.041 14.1 0.5 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain MtrB_PioB PF11854.8 GBG75969.1 - 0.023 13.1 0.1 0.031 12.6 0.1 1.1 1 0 0 1 1 1 0 Putative outer membrane beta-barrel porin, MtrB/PioB Myb_DNA-bind_3 PF12776.7 GBG75969.1 - 0.11 13.5 0.5 0.17 12.8 0.5 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain FlaF PF07309.11 GBG75969.1 - 0.18 11.9 0.8 0.3 11.1 0.2 1.6 2 0 0 2 2 2 0 Flagellar protein FlaF RVT_1 PF00078.27 GBG75970.1 - 5.3e-08 32.6 0.0 8.7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.24 GBG75971.1 - 1e-12 48.5 0.3 2.3e-12 47.4 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pox_Ag35 PF03286.14 GBG75971.1 - 2.8 7.7 5.6 0.66 9.7 2.0 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein rve PF00665.26 GBG75972.1 - 1.6e-07 31.6 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain SDA1 PF05285.12 GBG75973.1 - 0.28 10.6 5.2 0.32 10.4 5.2 1.1 1 0 0 1 1 1 0 SDA1 HPIP_like PF18524.1 GBG75973.1 - 1.4 8.7 7.1 53 3.7 0.2 4.0 2 1 2 4 4 4 0 High potential iron-sulfur protein like UQ_con PF00179.26 GBG75974.1 - 1.6e-52 176.9 0.0 1.8e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PNMA PF14893.6 GBG75975.1 - 0.013 14.9 0.2 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 PNMA Copine PF07002.16 GBG75976.1 - 1e-63 214.8 0.0 1.2e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Copine zf-C3HC4_3 PF13920.6 GBG75976.1 - 8.4e-07 28.8 8.1 1.3e-06 28.2 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) vWA-TerF-like PF10138.9 GBG75976.1 - 0.00017 21.7 0.0 0.00037 20.7 0.0 1.4 1 1 0 1 1 1 1 vWA found in TerF C terminus zf-C3HC4 PF00097.25 GBG75976.1 - 0.053 13.4 5.9 0.14 12.1 5.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG75976.1 - 0.062 13.2 8.5 0.25 11.2 8.8 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG75976.1 - 0.082 12.9 10.4 0.17 11.9 10.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG75976.1 - 0.14 12.2 1.7 0.38 10.8 1.7 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 GBG75976.1 - 0.62 10.4 10.6 1.3 9.5 10.6 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 GBG75976.1 - 3.6 7.5 8.0 6.8 6.6 8.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RVT_1 PF00078.27 GBG75978.1 - 1.3e-36 126.2 0.1 2.3e-36 125.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG75978.1 - 7.3e-31 106.6 0.4 1.9e-30 105.3 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG75978.1 - 1.2e-30 105.5 0.0 3.6e-30 103.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG75978.1 - 2.3e-16 59.7 0.2 4.7e-16 58.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG75978.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Helicase_C PF00271.31 GBG75979.1 - 0.0047 17.3 0.0 0.0081 16.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3143 PF11341.8 GBG75980.1 - 0.086 13.2 0.6 0.17 12.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) DEAD PF00270.29 GBG75981.1 - 2e-08 34.2 0.0 3.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Paf1 PF03985.13 GBG75981.1 - 0.39 9.7 9.3 0.61 9.0 9.3 1.3 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 GBG75981.1 - 0.47 9.7 5.5 0.7 9.2 5.5 1.3 1 0 0 1 1 1 0 NOA36 protein RibD_C PF01872.17 GBG75984.1 - 2.6e-42 144.9 0.0 3.8e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 RibD C-terminal domain DUF1768 PF08719.11 GBG75984.1 - 6.8e-30 104.4 0.0 1e-29 103.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) dCMP_cyt_deam_1 PF00383.23 GBG75984.1 - 2.5e-07 30.5 0.0 6.8e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GBG75984.1 - 0.032 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase Fibrillarin PF01269.17 GBG75985.1 - 5.4e-111 369.1 0.1 6.2e-111 369.0 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 GBG75985.1 - 2.9e-06 27.1 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 GBG75985.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 GBG75985.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 GBG75985.1 - 0.052 13.6 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase RT_RNaseH_2 PF17919.1 GBG75986.1 - 2.1e-16 59.7 0.0 8.8e-16 57.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG75986.1 - 6.7e-14 52.1 0.0 5.3e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG75986.1 - 1.5e-10 41.0 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG75986.1 - 1.2e-08 35.4 0.2 4.7e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG75986.1 - 3.1e-05 24.5 0.2 0.0001 22.8 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG75986.1 - 0.0025 17.6 0.6 0.0048 16.7 0.6 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG75986.1 - 0.0062 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Amidohydro_1 PF01979.20 GBG75987.1 - 4.5e-19 69.0 0.0 2.4e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.14 GBG75987.1 - 0.00054 19.8 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase DUF1071 PF06378.11 GBG75988.1 - 0.21 11.2 0.0 0.53 9.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1071) DDE_Tnp_4 PF13359.6 GBG75990.1 - 1e-24 87.0 0.0 1.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG75990.1 - 2.7e-15 56.5 0.0 3.9e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG75991.1 - 2.6e-11 43.8 2.8 2.8e-11 43.6 0.3 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Ssl1 PF04056.14 GBG75993.1 - 5.5e-79 264.5 0.0 7.7e-79 264.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 GBG75993.1 - 1.2e-15 57.5 14.3 1.2e-15 57.5 14.3 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 GBG75993.1 - 1.4e-08 35.4 0.0 2.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GBG75993.1 - 0.09 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Ribosomal_S16 PF00886.19 GBG75994.1 - 2.8e-10 40.1 0.0 3.9e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 HTH_33 PF13592.6 GBG75994.1 - 0.049 13.3 0.1 0.089 12.5 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix PDR_assoc PF08370.11 GBG75994.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Plant PDR ABC transporter associated MAP65_ASE1 PF03999.12 GBG75995.1 - 1.1e-95 321.6 3.0 1.4e-95 321.2 3.0 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) zf-CCHC_4 PF14392.6 GBG75996.1 - 0.052 13.3 0.5 0.12 12.2 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG75996.1 - 0.39 10.6 3.9 1.2 9.0 3.9 1.9 1 0 0 1 1 1 0 Zinc knuckle CN_hydrolase PF00795.22 GBG75997.1 - 1.6e-48 165.3 0.0 2.5e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Beta_helix PF13229.6 GBG75998.1 - 1.2e-10 41.5 0.9 0.00017 21.5 0.0 2.5 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 GBG75998.1 - 0.0017 17.7 0.1 0.44 9.8 0.0 2.3 2 0 0 2 2 2 2 Periplasmic copper-binding protein (NosD) HEAT PF02985.22 GBG75999.1 - 8.1e-17 59.9 2.5 0.0012 18.9 0.0 8.1 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 GBG75999.1 - 2.6e-14 53.3 4.7 2.4e-06 27.9 0.0 9.0 10 1 1 11 11 10 2 HEAT-like repeat IBN_N PF03810.19 GBG75999.1 - 1.7e-11 43.8 1.5 6.6e-11 42.0 0.4 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 GBG75999.1 - 1.4e-09 38.4 1.6 0.0098 16.5 0.1 6.2 5 2 1 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 GBG75999.1 - 4.5e-06 27.0 7.0 1.9 8.9 0.0 7.2 5 2 4 9 9 9 4 HEAT repeats RTP1_C1 PF10363.9 GBG75999.1 - 0.00097 19.3 5.9 0.019 15.1 0.1 4.6 6 0 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 GBG75999.1 - 0.0027 16.9 0.3 1.1 8.4 0.0 3.0 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain MMS19_N PF14500.6 GBG75999.1 - 0.014 15.0 4.5 0.075 12.6 0.1 3.3 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.7 GBG75999.1 - 0.032 14.3 0.2 0.66 10.0 0.0 3.3 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF2612 PF11041.8 GBG75999.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) DUF577 PF04510.12 GBG75999.1 - 0.089 12.7 0.8 0.53 10.2 0.0 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF577) Presenilin PF01080.17 GBG76000.1 - 0.37 9.5 12.2 0.49 9.1 12.2 1.3 1 0 0 1 1 1 0 Presenilin Dapper PF15268.6 GBG76000.1 - 3.1 6.5 9.2 3.6 6.3 9.2 1.1 1 0 0 1 1 1 0 Dapper zf-CCHC PF00098.23 GBG76001.1 - 0.3 11.2 1.9 0.64 10.2 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.29 GBG76002.1 - 4.4e-35 121.0 0.0 1.1e-34 119.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG76002.1 - 6.4e-24 84.4 0.0 1.3e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 GBG76002.1 - 0.035 13.4 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 GBG76002.1 - 0.078 13.0 0.0 0.61 10.1 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Arf PF00025.21 GBG76003.1 - 1.4e-41 141.9 0.0 8.8e-26 90.4 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 GBG76003.1 - 0.00045 19.7 0.1 0.047 13.1 0.1 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GBG76003.1 - 0.0033 16.7 0.1 0.84 8.7 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit ABC_tran PF00005.27 GBG76003.1 - 0.037 14.5 0.0 0.057 13.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter 6PF2K PF01591.18 GBG76003.1 - 0.041 13.2 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase GPI2 PF06432.11 GBG76004.1 - 1.8e-84 283.5 0.0 4.3e-84 282.3 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase SR-25 PF10500.9 GBG76004.1 - 0.038 13.6 14.7 0.09 12.4 14.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Myc_N PF01056.18 GBG76004.1 - 0.41 10.5 1.7 0.5 10.2 0.0 1.8 2 0 0 2 2 2 0 Myc amino-terminal region Transketolase_N PF00456.21 GBG76005.1 - 1.2e-150 501.2 0.1 1.9e-150 500.5 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GBG76005.1 - 2.2e-43 148.0 0.1 4.4e-43 147.0 0.1 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GBG76005.1 - 5.8e-12 45.6 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GBG76005.1 - 0.00027 20.2 0.0 0.0061 15.8 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 GBG76005.1 - 0.0018 17.3 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component RT_RNaseH PF17917.1 GBG76006.1 - 1.4e-53 179.5 0.0 6.1e-27 94.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76006.1 - 3.5e-53 177.8 0.0 4e-21 74.9 0.0 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76006.1 - 7.4e-27 94.3 0.0 1.1e-16 61.0 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76006.1 - 8.5e-16 57.8 0.3 3.7e-14 52.6 0.0 3.2 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG76006.1 - 5.9e-12 45.3 0.0 2e-11 43.6 0.0 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG76006.1 - 4.2e-10 39.8 0.0 9.8e-07 29.0 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG76006.1 - 8.5e-05 22.7 0.0 0.00028 21.0 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG76006.1 - 0.025 15.2 0.0 0.06 14.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG76007.1 - 0.0026 18.4 0.0 0.0055 17.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Transketolase_N PF00456.21 GBG76008.1 - 2.6e-151 503.3 0.1 4.2e-151 502.6 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GBG76008.1 - 2.4e-43 147.9 0.1 4.4e-43 147.0 0.1 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GBG76008.1 - 5.9e-12 45.6 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 GBG76008.1 - 0.0019 17.2 0.1 0.0033 16.4 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GBG76008.1 - 0.0028 16.9 0.0 0.019 14.2 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase zf-CCHC PF00098.23 GBG76010.1 - 6.4e-05 22.8 0.9 0.0001 22.2 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG76010.1 - 0.11 12.3 1.4 0.23 11.3 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG76011.1 - 1.6e-36 125.9 0.1 2.8e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76011.1 - 2.2e-27 95.0 0.0 6.8e-27 93.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76011.1 - 2.3e-17 63.2 0.0 6.3e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG76011.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76011.1 - 3.7e-07 30.7 0.0 1e-06 29.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76011.1 - 8.6e-06 26.2 0.0 2.8e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG76011.1 - 0.01 15.6 0.0 0.029 14.2 0.0 1.7 2 0 0 2 2 2 0 Aspartyl protease LEA_3 PF03242.13 GBG76011.1 - 1.9 9.2 5.9 9.4 7.0 0.0 3.8 3 0 0 3 3 3 0 Late embryogenesis abundant protein DUF4716 PF15837.5 GBG76012.1 - 0.1 12.7 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4716) RT_RNaseH_2 PF17919.1 GBG76013.1 - 2.2e-28 98.2 0.0 5e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76013.1 - 2.8e-28 98.2 0.2 6e-28 97.2 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76013.1 - 3.1e-14 53.2 0.0 8.4e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG76013.1 - 0.00041 20.1 0.5 0.0033 17.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) CobU PF02283.16 GBG76013.1 - 0.84 9.2 2.8 34 3.9 0.2 3.5 3 0 0 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase zf-CCHC PF00098.23 GBG76014.1 - 2.4e-07 30.5 2.4 4.3e-07 29.7 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG76014.1 - 0.26 11.1 0.9 0.49 10.2 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle LMBR1 PF04791.16 GBG76014.1 - 1.2 8.0 3.2 1.3 7.8 3.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Methyltransf_16 PF10294.9 GBG76015.1 - 5.9e-09 35.9 0.0 0.00017 21.4 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 GBG76015.1 - 0.011 15.6 0.1 0.051 13.4 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Myb_DNA-bind_4 PF13837.6 GBG76016.1 - 2.9e-05 24.3 1.4 0.0001 22.6 0.2 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain IQ PF00612.27 GBG76018.1 - 1.3e-07 30.7 4.4 1.6e-06 27.4 0.6 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif RT_RNaseH_2 PF17919.1 GBG76020.1 - 1.4e-35 121.3 0.0 1.1e-34 118.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76020.1 - 1.5e-31 108.7 0.1 3.6e-31 107.5 0.1 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG76020.1 - 0.00025 20.9 0.8 0.0006 19.7 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG76020.1 - 1.2 9.4 3.7 2.4 8.4 3.7 1.6 1 0 0 1 1 1 0 Zinc knuckle H_PPase PF03030.16 GBG76021.1 - 3.3e-249 828.9 37.3 3.9e-249 828.7 37.3 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase NT5C PF06941.12 GBG76022.1 - 0.0047 16.8 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Dimer_Tnp_hAT PF05699.14 GBG76023.1 - 2.2e-08 33.7 0.1 4.6e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region dUTPase PF00692.19 GBG76026.1 - 7.4e-33 113.0 0.0 9.9e-33 112.6 0.0 1.2 1 0 0 1 1 1 1 dUTPase Prothymosin PF03247.14 GBG76027.1 - 0.22 12.0 43.8 0.31 11.5 43.8 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family NOA36 PF06524.12 GBG76027.1 - 2.3 7.5 32.3 2.7 7.2 32.3 1.1 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 GBG76027.1 - 2.3 7.1 28.7 2.8 6.8 28.7 1.1 1 0 0 1 1 1 0 Paf1 Afi1 PF07792.12 GBG76027.1 - 3.7 8.0 16.4 4.4 7.8 16.4 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking V_ATPase_I PF01496.19 GBG76027.1 - 8.1 4.2 12.8 8.8 4.1 12.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPR3 PF03666.13 GBG76027.1 - 9.3 4.9 14.2 10 4.8 14.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAN_4 PF14295.6 GBG76028.1 - 0.0055 16.6 2.5 0.0095 15.8 2.5 1.4 1 0 0 1 1 1 1 PAN domain Myb_DNA-bind_4 PF13837.6 GBG76029.1 - 1.6e-12 47.6 12.4 1.5e-07 31.7 3.0 3.2 4 0 0 4 4 4 2 Myb/SANT-like DNA-binding domain PAN_4 PF14295.6 GBG76030.1 - 0.023 14.6 2.8 0.037 13.9 2.8 1.4 1 0 0 1 1 1 0 PAN domain PAN_1 PF00024.26 GBG76031.1 - 0.0041 17.0 1.3 0.0068 16.4 0.5 1.7 1 1 1 2 2 2 1 PAN domain PAN_4 PF14295.6 GBG76031.1 - 0.0059 16.5 1.4 0.0083 16.0 1.4 1.3 1 0 0 1 1 1 1 PAN domain dUTPase PF00692.19 GBG76032.1 - 2e-34 118.0 0.0 2.6e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 dUTPase Birna_VP5 PF03042.14 GBG76032.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP5 protein UPF0561 PF10573.9 GBG76033.1 - 9.9 6.3 9.7 1.3 9.1 1.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 DSX_dimer PF08828.10 GBG76035.1 - 0.04 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Doublesex dimerisation domain PAN_4 PF14295.6 GBG76036.1 - 1.4e-05 24.9 4.1 2.5e-05 24.1 4.1 1.5 1 0 0 1 1 1 1 PAN domain DUF659 PF04937.15 GBG76040.1 - 3.9e-19 69.0 0.0 7.3e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG76041.1 - 5.1e-34 116.3 0.1 1e-33 115.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76041.1 - 6.4e-28 97.1 0.0 1.3e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76041.1 - 9.1e-27 94.0 0.2 1.4e-26 93.4 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAN_4 PF14295.6 GBG76042.1 - 0.00051 19.9 5.9 0.00073 19.4 5.9 1.2 1 0 0 1 1 1 1 PAN domain RT_RNaseH PF17917.1 GBG76043.1 - 1.9e-28 98.8 0.0 3.7e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76043.1 - 9.9e-27 92.9 0.0 2e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-C3H1 PF10650.9 GBG76043.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative zinc-finger domain PAN_4 PF14295.6 GBG76044.1 - 0.0026 17.6 5.7 0.0039 17.1 5.7 1.3 1 0 0 1 1 1 1 PAN domain SDA1 PF05285.12 GBG76045.1 - 1.4 8.2 45.3 0.4 10.1 24.8 2.6 2 0 0 2 2 2 0 SDA1 RVT_1 PF00078.27 GBG76046.1 - 1.7e-28 99.7 0.0 2.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76046.1 - 3.5e-19 68.7 0.0 1.3e-15 57.3 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76046.1 - 2.7e-08 34.0 0.0 7.7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Conotoxin PF02950.17 GBG76047.1 - 0.051 14.6 0.0 0.24 12.4 0.0 2.2 1 0 0 1 1 1 0 Conotoxin zf-CCHC PF00098.23 GBG76048.1 - 0.026 14.6 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle PAN_4 PF14295.6 GBG76049.1 - 0.00022 21.0 5.6 0.00034 20.5 5.6 1.3 1 0 0 1 1 1 1 PAN domain RVT_1 PF00078.27 GBG76052.1 - 4.6e-26 91.7 0.0 1e-25 90.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76052.1 - 0.00022 21.4 0.0 0.00059 20.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG76052.1 - 0.0019 18.4 0.0 0.018 15.3 0.0 2.7 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG76052.1 - 0.07 13.8 0.0 0.64 10.7 0.0 2.6 3 0 0 3 3 3 0 Aspartyl protease CENP-B_dimeris PF09026.10 GBG76053.1 - 1.4 9.4 6.1 2.6 8.5 6.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase_Tyr PF07714.17 GBG76055.1 - 1.4e-11 44.1 0.1 5e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76055.1 - 3.6e-11 42.9 0.3 4.3e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 GBG76055.1 - 6.8e-07 29.9 17.6 4.9e-05 24.0 0.3 5.9 5 1 1 6 6 6 2 WD domain, G-beta repeat Myb_DNA-bind_4 PF13837.6 GBG76055.1 - 1.1e-05 25.8 0.5 1.1e-05 25.8 0.5 3.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG76055.1 - 5.9e-05 23.1 1.7 5.9e-05 23.1 1.7 3.0 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG76055.1 - 0.002 18.3 1.3 0.0046 17.1 0.3 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG76055.1 - 0.021 15.1 0.6 0.092 13.0 0.6 2.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain HTH_57 PF18679.1 GBG76055.1 - 1.4 9.3 6.6 2.8 8.3 5.2 2.3 2 0 0 2 2 2 0 ThcOx helix turn helix domain PCAF_N PF06466.11 GBG76055.1 - 8.6 5.8 7.9 3.1 7.3 0.6 2.8 2 1 0 2 2 2 0 PCAF (P300/CBP-associated factor) N-terminal domain RT_RNaseH_2 PF17919.1 GBG76056.1 - 6e-27 93.6 0.0 1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76056.1 - 5e-24 84.6 0.0 8.2e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG76056.1 - 0.11 10.7 8.8 0.13 10.4 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG76056.1 - 0.91 8.9 11.6 1.2 8.5 11.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG76056.1 - 1.2 7.3 10.5 1.6 6.9 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 GBG76056.1 - 5.5 6.9 19.0 9.6 6.2 19.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) WD40 PF00400.32 GBG76057.1 - 2.6e-22 78.7 13.2 4.6e-06 27.3 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GBG76057.1 - 1.3e-13 50.6 2.9 0.00011 21.2 0.1 4.0 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 GBG76057.1 - 4.3e-12 46.2 0.8 0.036 14.4 0.0 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GBG76057.1 - 0.054 12.2 0.0 2.3 6.9 0.0 2.7 2 1 2 4 4 4 0 Nup133 N terminal like Nbas_N PF15492.6 GBG76057.1 - 0.084 12.2 0.0 0.64 9.3 0.0 2.4 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF846 PF05832.12 GBG76058.1 - 6.6e-48 162.3 9.2 8e-48 162.0 9.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4870 PF09685.10 GBG76058.1 - 0.037 14.1 0.7 0.037 14.1 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) YwiC PF14256.6 GBG76058.1 - 0.086 13.1 6.9 2.3 8.6 2.2 2.4 2 1 0 2 2 2 0 YwiC-like protein DUF2232 PF09991.9 GBG76058.1 - 0.46 9.6 10.3 0.49 9.5 1.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF5317 PF17248.2 GBG76058.1 - 4.8 7.2 9.9 0.66 10.0 3.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5317) NPH3 PF03000.14 GBG76060.1 - 3.3e-29 102.3 0.1 9.9e-29 100.8 0.0 1.8 2 0 0 2 2 2 1 NPH3 family BTB PF00651.31 GBG76060.1 - 0.007 16.6 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Exonuc_VII_L PF02601.15 GBG76060.1 - 0.27 10.8 6.9 0.42 10.1 6.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ORF6C PF10552.9 GBG76060.1 - 2 8.5 6.1 2.8 8.1 5.1 1.7 1 1 0 1 1 1 0 ORF6C domain TSC22 PF01166.18 GBG76060.1 - 2.3 8.6 7.7 0.56 10.6 0.7 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family Tho2 PF11262.8 GBG76060.1 - 6.7 5.8 6.2 11 5.2 6.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Pyr_redox_2 PF07992.14 GBG76061.1 - 2.2e-59 201.1 0.3 3.2e-59 200.6 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GBG76061.1 - 1.3e-32 112.3 0.7 2.5e-32 111.4 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GBG76061.1 - 6.2e-22 77.9 2.1 1.6e-21 76.6 0.5 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG76061.1 - 4e-17 62.4 0.2 5.5e-17 62.0 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GBG76061.1 - 0.0033 16.6 0.1 0.0076 15.4 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) UCH PF00443.29 GBG76062.1 - 8.1e-41 140.2 0.0 1.1e-40 139.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG76062.1 - 3.8e-11 43.2 0.0 6.4e-10 39.1 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 GBG76062.1 - 5.1e-05 22.9 2.5 0.00021 21.0 2.5 2.2 1 0 0 1 1 1 1 Ubiquitin interaction motif Ribonuclease_3 PF00636.26 GBG76063.1 - 1.3e-18 67.5 0.0 5.6e-18 65.5 0.0 2.2 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GBG76063.1 - 3.9e-12 46.4 0.0 1.1e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease-III-like AP3D1 PF06375.11 GBG76063.1 - 1.3 9.2 10.3 1.8 8.8 9.1 1.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Myb_DNA-bind_4 PF13837.6 GBG76064.1 - 1.3e-05 25.5 1.1 3e-05 24.3 1.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CENP-F_leu_zip PF10473.9 GBG76064.1 - 0.063 13.3 1.0 0.14 12.2 1.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TetR_C_24 PF17932.1 GBG76064.1 - 0.067 13.5 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3347 PF11827.8 GBG76064.1 - 0.55 10.4 3.3 0.32 11.2 0.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) FUSC PF04632.12 GBG76064.1 - 0.64 8.5 5.1 0.92 8.0 5.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family RT_RNaseH PF17917.1 GBG76065.1 - 7.9e-23 80.7 0.0 1.7e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76065.1 - 1.1e-21 76.7 0.0 2.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76065.1 - 1.7e-07 31.0 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG76065.1 - 5e-06 27.0 0.0 1.2e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76065.1 - 0.00016 22.2 0.0 0.00034 21.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76065.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG76065.1 - 0.038 13.7 1.8 0.039 13.6 0.2 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG76065.1 - 0.039 13.8 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG76065.1 - 0.16 12.1 3.2 0.22 11.7 1.7 2.0 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG76066.1 - 5.8e-24 84.8 0.0 9.9e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76066.1 - 4.6e-16 58.7 0.0 4.7e-15 55.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76066.1 - 6.5e-05 23.2 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SprA-related PF12118.8 GBG76067.1 - 0.0013 17.9 2.0 0.0019 17.4 2.0 1.1 1 0 0 1 1 1 1 SprA-related family BT1 PF03092.16 GBG76067.1 - 0.27 9.4 4.0 0.37 9.0 4.0 1.1 1 0 0 1 1 1 0 BT1 family Borrelia_P83 PF05262.11 GBG76067.1 - 0.8 8.1 6.8 1 7.8 6.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Tyrosinase PF00264.20 GBG76068.1 - 6.1e-32 111.7 10.7 6.9e-17 62.5 1.7 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG76068.1 - 8.6e-10 38.3 0.2 1.8e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain RVT_1 PF00078.27 GBG76069.1 - 2.2e-21 76.4 0.0 7.4e-21 74.7 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG76069.1 - 1.2e-14 54.6 0.1 2.2e-06 28.1 0.1 3.0 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76069.1 - 1.4e-13 51.3 0.0 2.5e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG76069.1 - 9.4e-13 48.1 0.0 7.7e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG76069.1 - 2.9e-07 30.7 1.1 0.091 13.0 0.1 3.9 2 1 1 3 3 3 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG76069.1 - 5.3e-07 29.5 0.0 0.0031 17.3 0.1 2.5 2 0 0 2 2 2 2 Aspartyl protease DUF4187 PF13821.6 GBG76069.1 - 0.072 12.9 0.8 0.22 11.4 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) YL1 PF05764.13 GBG76070.1 - 0.0093 16.1 25.1 0.0093 16.1 25.1 1.7 2 0 0 2 2 2 1 YL1 nuclear protein Sigma70_ner PF04546.13 GBG76070.1 - 0.016 15.1 14.8 0.016 15.1 14.8 3.2 3 0 0 3 3 3 0 Sigma-70, non-essential region CPSF100_C PF13299.6 GBG76070.1 - 0.12 12.6 12.8 0.072 13.3 6.6 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Mpp10 PF04006.12 GBG76070.1 - 0.55 8.6 34.7 0.0089 14.5 22.2 2.1 2 0 0 2 2 2 0 Mpp10 protein CDC27 PF09507.10 GBG76070.1 - 3 7.1 18.9 5.5 6.3 18.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Usp PF00582.26 GBG76070.1 - 4.4 7.8 16.5 0.52 10.8 11.0 2.0 2 0 0 2 2 2 0 Universal stress protein family EIIBC-GUT_N PF03612.14 GBG76070.1 - 8.9 6.0 7.6 1.1 8.9 2.7 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus zf-CCHC PF00098.23 GBG76072.1 - 0.0014 18.6 3.7 0.0025 17.8 3.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG76072.1 - 0.19 11.5 0.5 0.33 10.7 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle TFIIA PF03153.13 GBG76072.1 - 8.2 6.3 13.7 0.059 13.4 1.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 GBG76072.1 - 9.7 4.2 6.1 13 3.7 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDE_Tnp_4 PF13359.6 GBG76073.1 - 1.2e-30 106.2 0.0 2.3e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76073.1 - 6.1e-12 45.6 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Tyrosinase PF00264.20 GBG76075.1 - 1e-32 114.2 10.5 2.3e-18 67.3 1.0 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG76075.1 - 6.2e-15 54.7 0.2 1.3e-14 53.6 0.2 1.6 1 0 0 1 1 1 1 Polyphenol oxidase middle domain SICA_C PF12879.7 GBG76077.1 - 0.023 14.7 0.7 0.076 13.0 0.2 2.1 2 0 0 2 2 2 0 SICA C-terminal inner membrane domain Myb_DNA-bind_4 PF13837.6 GBG76079.1 - 9.4e-05 22.7 0.5 0.0002 21.7 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG76079.1 - 0.052 13.8 0.3 0.18 12.0 0.3 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG76081.1 - 1.5e-28 98.8 0.0 2.3e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76081.1 - 5.3e-27 94.2 0.0 8.5e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76081.1 - 1.6e-08 34.3 0.1 2.6e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG76081.1 - 0.0053 16.6 0.1 0.016 15.1 0.1 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2249) MAPEG PF01124.18 GBG76084.1 - 1.5e-21 76.7 1.3 1.9e-21 76.3 1.3 1.1 1 0 0 1 1 1 1 MAPEG family SH3_15 PF18346.1 GBG76085.1 - 3.7e-81 267.4 40.3 3.6e-10 40.0 0.2 12.5 11 1 0 11 11 11 10 Mind bomb SH3 repeat domain Pkinase_Tyr PF07714.17 GBG76085.1 - 9.7e-37 126.6 0.0 1.5e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76085.1 - 3.4e-36 125.0 0.0 5.5e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-RING_UBOX PF13445.6 GBG76085.1 - 9.7e-06 25.5 7.6 2.3e-05 24.3 7.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger NHase_beta PF02211.15 GBG76085.1 - 1.2e-05 25.5 2.1 7.7 6.5 0.0 6.6 5 2 2 7 7 7 1 Nitrile hydratase beta subunit zf-C3HC4_2 PF13923.6 GBG76085.1 - 0.00029 20.6 6.4 0.001 18.9 6.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG76085.1 - 0.0006 19.6 5.4 0.0014 18.5 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG76085.1 - 0.00061 20.1 6.1 0.0015 18.8 6.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG76085.1 - 0.00077 19.4 4.0 0.00077 19.4 4.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Ribosomal_L19 PF01245.20 GBG76085.1 - 0.00084 19.3 0.4 26 4.8 0.0 6.2 8 0 0 8 8 7 0 Ribosomal protein L19 MS_channel PF00924.18 GBG76085.1 - 0.013 15.0 0.2 18 4.8 0.0 4.6 5 0 0 5 5 5 0 Mechanosensitive ion channel zf-C3HC4_4 PF15227.6 GBG76085.1 - 0.083 13.1 4.6 0.28 11.4 4.6 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING APH PF01636.23 GBG76085.1 - 0.12 12.3 0.1 7.4 6.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-rbx1 PF12678.7 GBG76085.1 - 0.13 12.6 4.4 0.3 11.4 4.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GBG76085.1 - 0.18 11.9 2.9 0.74 9.9 2.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GBG76085.1 - 0.35 10.8 5.2 1.1 9.1 5.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 GBG76085.1 - 0.78 9.6 4.0 11 6.0 0.3 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Aminotran_1_2 PF00155.21 GBG76086.1 - 1.2e-51 176.0 0.0 1.5e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GBG76086.1 - 5.7e-07 28.4 0.0 8.6e-07 27.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 GBG76086.1 - 0.00059 19.2 0.1 0.0016 17.8 0.0 1.7 1 1 1 2 2 2 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 GBG76086.1 - 0.035 12.8 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 GBG76086.1 - 0.043 12.8 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Coatamer_beta_C PF07718.12 GBG76087.1 - 0.0026 17.7 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 GBG76087.1 - 0.035 14.5 7.7 0.48 10.9 0.5 5.2 5 2 2 7 7 7 0 HEAT repeats Galactosyl_T PF01762.21 GBG76088.1 - 1.1e-43 149.3 0.0 1.5e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF4094 PF13334.6 GBG76088.1 - 1.3e-05 25.5 0.6 0.00039 20.8 0.6 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4094) Fringe PF02434.16 GBG76088.1 - 0.00033 20.2 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF2730 PF10805.8 GBG76088.1 - 0.24 11.5 0.9 0.44 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) F-box PF00646.33 GBG76089.1 - 2.4e-09 36.8 2.2 5.8e-09 35.6 2.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG76089.1 - 1.7e-06 27.8 2.9 3.2e-06 26.9 2.9 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 GBG76089.1 - 0.00085 19.2 0.1 0.00085 19.2 0.1 2.1 2 1 1 3 3 3 1 F-box Macoilin PF09726.9 GBG76089.1 - 7.3 5.0 6.4 9.7 4.6 6.4 1.1 1 0 0 1 1 1 0 Macoilin family Fib_alpha PF08702.10 GBG76090.1 - 0.012 15.8 6.2 0.012 15.8 6.2 6.1 2 2 3 6 6 6 0 Fibrinogen alpha/beta chain family DapB_C PF05173.14 GBG76090.1 - 0.043 13.8 0.8 0.23 11.5 0.8 2.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Phage_tail_APC PF16778.5 GBG76090.1 - 1.3 9.0 4.2 2.9 7.8 0.1 3.5 2 1 0 3 3 3 0 Phage tail assembly chaperone protein FHA PF00498.26 GBG76091.1 - 2e-18 66.5 0.1 3.8e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GBG76091.1 - 1.3e-10 41.4 0.0 2.2e-08 34.3 0.0 2.3 1 1 1 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain SH3_3 PF08239.11 GBG76091.1 - 0.01 16.1 0.1 7 7.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain FHA PF00498.26 GBG76092.1 - 2.1e-18 66.4 0.1 3.1e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GBG76092.1 - 1.1e-11 44.8 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 GBG76092.1 - 0.011 16.0 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 FHA domain B3 PF02362.21 GBG76093.1 - 3.9e-26 90.9 0.0 9.1e-26 89.7 0.0 1.7 1 0 0 1 1 1 1 B3 DNA binding domain DUF3995 PF13160.6 GBG76093.1 - 2 8.8 5.5 5.1 7.5 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) ACC_epsilon PF13822.6 GBG76093.1 - 9.8 6.9 17.3 18 6.1 0.5 3.6 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit Goodbye PF17109.5 GBG76095.1 - 0.035 14.5 0.7 10 6.6 0.0 3.0 1 1 2 3 3 3 0 fungal STAND N-terminal Goodbye domain FERM_f0 PF16511.5 GBG76095.1 - 0.56 10.5 11.9 20 5.5 0.4 4.8 1 1 3 4 4 4 0 N-terminal or F0 domain of Talin-head FERM DUF4539 PF15072.6 GBG76096.1 - 3.6e-15 55.8 0.0 6.7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) RVT_1 PF00078.27 GBG76097.1 - 1.8e-20 73.4 0.0 3.3e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76097.1 - 1.8e-17 63.6 0.1 4.4e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76097.1 - 3.3e-12 46.3 0.0 1.1e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76097.1 - 9.1e-05 22.5 0.1 0.00026 21.0 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain PPTA PF01239.22 GBG76098.1 - 7.5e-35 117.6 23.9 7.8e-09 35.0 0.3 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 GBG76098.1 - 0.11 12.1 14.5 2.2 8.1 0.5 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4219) DWNN PF08783.11 GBG76099.1 - 1.5e-20 73.3 0.4 7.1e-15 55.1 0.0 2.8 2 0 0 2 2 2 2 DWNN domain zf-CCHC_2 PF13696.6 GBG76099.1 - 4.9e-13 48.6 14.7 7.9e-11 41.6 7.0 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-C3HC4_2 PF13923.6 GBG76099.1 - 2.1e-07 30.7 12.2 4.6e-07 29.6 12.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 GBG76099.1 - 4.3e-07 29.7 9.0 0.0027 17.7 1.3 2.5 2 0 0 2 2 2 2 Zinc knuckle U-box PF04564.15 GBG76099.1 - 6.2e-05 23.1 0.1 0.00028 21.0 0.1 2.2 2 0 0 2 2 1 1 U-box domain zf-C3HC4_3 PF13920.6 GBG76099.1 - 0.00028 20.7 11.1 0.00028 20.7 11.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG76099.1 - 0.0028 18.0 11.4 0.0083 16.4 11.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG76099.1 - 0.021 14.7 12.3 0.043 13.7 12.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG76099.1 - 0.022 14.8 8.8 0.046 13.8 8.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Paired_CXXCH_1 PF09699.10 GBG76099.1 - 0.037 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-RING_6 PF14835.6 GBG76099.1 - 0.19 11.6 4.0 0.45 10.4 4.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 GBG76099.1 - 0.49 10.6 12.1 1 9.6 12.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 GBG76099.1 - 1.1 9.3 17.8 0.039 13.9 11.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_10 PF16685.5 GBG76099.1 - 1.3 9.2 6.0 3.4 7.9 6.0 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 gag-asp_proteas PF13975.6 GBG76100.1 - 1.9e-06 28.4 0.0 9.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG76100.1 - 0.00044 19.8 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76100.1 - 0.0025 18.4 0.0 0.0093 16.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease ABC1 PF03109.16 GBG76101.1 - 1.1e-32 112.7 0.0 1.6e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 GBG76101.1 - 0.0006 19.2 0.0 0.0097 15.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 GBG76101.1 - 0.00067 19.7 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 GBG76101.1 - 0.032 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) rve_3 PF13683.6 GBG76102.1 - 0.052 13.3 0.2 0.34 10.7 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain rve PF00665.26 GBG76102.1 - 0.075 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain S1-like PF14444.6 GBG76102.1 - 0.085 12.8 0.0 6.1 6.9 0.0 2.5 2 0 0 2 2 2 0 S1-like DUF3863 PF12979.7 GBG76102.1 - 0.092 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) TPT PF03151.16 GBG76103.1 - 3.1e-08 33.3 27.4 3.9e-08 33.0 27.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG76103.1 - 0.016 15.4 18.9 0.016 15.4 18.9 2.3 2 0 0 2 2 2 0 EamA-like transporter family Bax1-I PF01027.20 GBG76104.1 - 4.3e-38 131.2 25.1 5.5e-38 130.9 25.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Galactosyl_T PF01762.21 GBG76105.1 - 1.5e-26 93.4 1.8 2.1e-16 60.3 0.0 2.8 3 0 0 3 3 3 2 Galactosyltransferase DUF4094 PF13334.6 GBG76105.1 - 4.8e-10 39.7 0.2 1.1e-09 38.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) Skp1 PF01466.19 GBG76107.1 - 2.6e-28 97.9 0.6 2.6e-28 97.9 0.6 2.2 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GBG76107.1 - 3.7e-28 97.5 0.6 8.1e-28 96.4 0.6 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Methyltransf_16 PF10294.9 GBG76107.1 - 0.053 13.3 0.5 0.079 12.7 0.5 1.2 1 0 0 1 1 1 0 Lysine methyltransferase BTB PF00651.31 GBG76107.1 - 0.11 12.8 0.3 0.53 10.5 0.3 1.9 1 1 0 1 1 1 0 BTB/POZ domain Integrase_H2C2 PF17921.1 GBG76108.1 - 2.3e-35 120.5 1.3 1.8e-18 66.4 0.2 3.7 3 0 0 3 3 3 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG76108.1 - 1.7e-33 116.0 0.2 3.5e-33 115.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76108.1 - 2.5e-30 105.1 0.0 8.5e-15 55.0 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG76108.1 - 2.2e-29 101.4 0.0 6e-29 100.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76108.1 - 2e-25 89.1 0.0 6.8e-25 87.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MCM PF00493.23 GBG76108.1 - 1.4e-24 86.5 0.1 3.3e-24 85.2 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GBG76108.1 - 7.9e-24 83.9 1.8 2.5e-23 82.3 1.8 1.9 1 0 0 1 1 1 1 MCM OB domain RVP_2 PF08284.11 GBG76108.1 - 6.2e-16 58.4 0.0 1.3e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76108.1 - 2.7e-13 50.3 0.0 9.3e-07 29.4 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG76108.1 - 1.3e-11 44.9 0.0 5.7e-06 26.8 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG76108.1 - 1.1e-09 38.1 0.0 0.0018 18.1 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease zf-H2C2 PF09337.10 GBG76108.1 - 7.4e-05 22.9 0.0 0.12 12.6 0.0 3.0 2 0 0 2 2 2 2 H2C2 zinc finger rve_3 PF13683.6 GBG76108.1 - 0.0036 17.0 0.0 2.8 7.8 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain AAA_16 PF13191.6 GBG76108.1 - 0.016 15.6 2.1 0.057 13.8 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Rhamno_transf PF11316.8 GBG76108.1 - 0.023 14.1 0.0 0.056 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative rhamnosyl transferase CCDC85 PF10226.9 GBG76108.1 - 0.095 12.4 0.6 0.21 11.2 0.6 1.5 1 0 0 1 1 1 0 CCDC85 family MCM PF00493.23 GBG76109.1 - 2.8e-34 118.2 0.0 4.6e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 GBG76109.1 - 2.1e-28 98.5 2.4 2.1e-28 98.5 2.4 2.2 3 0 0 3 3 3 1 MCM AAA-lid domain AAA_3 PF07726.11 GBG76109.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GBG76109.1 - 0.033 13.6 0.0 0.076 12.4 0.0 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI MCM_lid PF17855.1 GBG76110.1 - 1.6e-28 99.0 2.4 2.5e-28 98.3 2.4 1.3 1 0 0 1 1 1 1 MCM AAA-lid domain DUF5347 PF17282.2 GBG76115.1 - 0.015 15.6 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5347) RT_RNaseH_2 PF17919.1 GBG76116.1 - 2.8e-06 27.3 0.0 6.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76116.1 - 0.00011 22.4 0.0 0.00029 21.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG76116.1 - 0.0017 18.9 0.0 0.0046 17.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76116.1 - 0.0069 17.0 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG76116.1 - 0.0073 16.3 0.7 0.021 14.9 0.7 1.9 1 0 0 1 1 1 1 Zinc knuckle DUF3562 PF12085.8 GBG76118.1 - 0.12 12.0 1.3 0.37 10.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3562) SAP PF02037.27 GBG76121.1 - 0.014 15.2 0.1 0.045 13.5 0.1 2.0 1 0 0 1 1 1 0 SAP domain Retrotrans_gag PF03732.17 GBG76122.1 - 0.00027 21.1 2.0 0.00052 20.2 0.1 2.5 3 1 0 3 3 3 1 Retrotransposon gag protein GIT_CC PF16559.5 GBG76122.1 - 0.15 11.9 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor RT_RNaseH_2 PF17919.1 GBG76123.1 - 1.2e-26 92.7 0.0 2.5e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76123.1 - 3.3e-23 82.0 0.0 7.6e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76123.1 - 1.2e-19 70.2 0.4 5.1e-19 68.1 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76123.1 - 5.3e-17 62.1 0.0 7.8e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76123.1 - 5.6e-10 39.4 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG76123.1 - 0.041 14.1 0.0 0.041 14.1 0.0 1.9 2 0 0 2 2 2 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG76124.1 - 0.0025 18.0 0.5 0.024 14.9 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG76125.1 - 1.4e-33 114.9 0.0 2.9e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76125.1 - 2.4e-29 101.7 0.1 7.5e-29 100.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76125.1 - 5.5e-29 101.3 0.0 9.9e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76125.1 - 8.2e-17 61.1 0.8 1.7e-16 60.1 0.8 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain HalX PF08663.10 GBG76125.1 - 0.019 15.3 5.6 8.2 6.8 1.4 3.8 3 0 0 3 3 3 0 HalX domain DUF2802 PF10975.8 GBG76125.1 - 0.032 14.3 7.1 1.9 8.7 5.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Phage_GPO PF05929.11 GBG76125.1 - 0.19 11.3 5.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase EzrA PF06160.12 GBG76125.1 - 0.22 9.6 6.3 0.42 8.7 6.3 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4407 PF14362.6 GBG76125.1 - 0.4 10.0 2.6 1.2 8.5 2.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GBG76125.1 - 1.1 8.7 3.5 2 7.9 3.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4140 PF13600.6 GBG76125.1 - 1.7 9.1 6.6 22 5.6 1.5 3.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Cep57_MT_bd PF06657.13 GBG76125.1 - 5.5 7.5 10.1 0.14 12.6 1.4 2.8 4 0 0 4 4 3 0 Centrosome microtubule-binding domain of Cep57 RVT_1 PF00078.27 GBG76126.1 - 5.7e-24 84.9 0.1 1.3e-23 83.7 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76126.1 - 2.4e-20 72.4 0.0 6.1e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76126.1 - 3.1e-14 53.1 0.0 7.3e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG76126.1 - 1.6e-07 31.2 0.0 3.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76126.1 - 2.5e-06 28.1 0.0 5.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76126.1 - 1.1e-05 25.9 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG76126.1 - 0.00096 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG76127.1 - 2.8e-24 85.9 0.1 4.1e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76127.1 - 9.8e-21 73.7 0.0 2.3e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76127.1 - 1.4e-14 54.2 0.0 3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Coatomer_b_Cpla PF14806.6 GBG76127.1 - 0.18 11.8 0.1 20 5.2 0.0 2.3 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform Topoisom_bac PF01131.20 GBG76128.1 - 1.7e-36 126.2 1.5 6e-36 124.3 0.0 2.1 2 0 0 2 2 2 1 DNA topoisomerase RT_RNaseH_2 PF17919.1 GBG76128.1 - 3.5e-30 104.0 0.0 7e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76128.1 - 1.8e-29 102.1 0.0 4.2e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76128.1 - 6.6e-08 32.5 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain SPATA1_C PF15743.5 GBG76128.1 - 0.012 15.7 17.1 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus PIEZO PF15917.5 GBG76128.1 - 0.025 14.0 13.0 0.041 13.4 13.0 1.3 1 0 0 1 1 1 0 Piezo RVT_1 PF00078.27 GBG76128.1 - 0.037 13.5 0.1 0.083 12.4 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG76128.1 - 0.049 13.3 0.1 0.049 13.3 0.1 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PA26 PF04636.13 GBG76128.1 - 0.42 9.5 4.8 0.66 8.8 4.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM60A PF15396.6 GBG76128.1 - 2.4 8.1 5.9 4.3 7.3 5.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Asp_protease_2 PF13650.6 GBG76129.1 - 3.4e-08 34.0 0.0 1.1e-07 32.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76129.1 - 4e-08 33.7 0.2 1.3e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG76129.1 - 9.9e-07 28.6 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG76129.1 - 0.00018 21.3 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG76130.1 - 6e-26 90.4 0.0 1.3e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76130.1 - 1.8e-20 73.2 0.1 7.4e-20 71.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase PhyH PF05721.13 GBG76130.1 - 0.18 12.1 1.8 16 5.7 0.0 2.4 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) gag-asp_proteas PF13975.6 GBG76131.1 - 1.2e-11 45.0 0.0 5.9e-11 42.8 0.1 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76131.1 - 1.1e-09 38.8 0.1 3.2e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG76131.1 - 1.3e-08 35.0 0.0 0.0047 17.2 0.0 3.1 3 0 0 3 3 3 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG76131.1 - 0.00082 19.2 0.6 0.0035 17.1 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG76131.1 - 0.0036 17.6 0.0 0.0099 16.2 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-FCS PF06467.14 GBG76131.1 - 0.11 12.5 0.3 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CCHC PF00098.23 GBG76131.1 - 1.3 9.2 3.4 2.9 8.1 3.4 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG76132.1 - 6.2e-34 117.5 0.2 1e-33 116.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76132.1 - 1.6e-05 24.7 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76132.1 - 0.00025 21.6 0.0 0.0006 20.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76132.1 - 0.03 14.9 0.0 0.09 13.4 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG76132.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) CSN5_C PF18323.1 GBG76133.1 - 3.9 8.5 12.8 0.86 10.6 0.2 2.8 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain rve PF00665.26 GBG76134.1 - 3e-09 37.1 0.0 8e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG76134.1 - 0.063 13.5 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein SlyX PF04102.12 GBG76134.1 - 4 8.1 12.6 0.14 12.8 0.5 3.6 4 0 0 4 4 4 0 SlyX Topoisom_bac PF01131.20 GBG76135.1 - 1.5e-30 106.5 0.0 1.7e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase RT_RNaseH_2 PF17919.1 GBG76137.1 - 1e-65 218.0 0.2 2.8e-33 113.9 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76137.1 - 1.2e-57 192.6 2.2 8.2e-29 100.0 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76137.1 - 2.4e-27 95.9 5.7 4.7e-13 49.2 0.2 3.4 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76137.1 - 4.4e-21 74.7 0.1 5.4e-17 61.6 0.1 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain Toprim PF01751.22 GBG76137.1 - 4.2e-05 23.7 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 Toprim domain zf-H2C2 PF09337.10 GBG76137.1 - 0.00015 21.9 0.1 0.0025 18.0 0.0 2.6 2 0 0 2 2 2 1 H2C2 zinc finger rve PF00665.26 GBG76137.1 - 0.001 19.2 0.0 0.0038 17.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain NAAA-beta PF15508.6 GBG76137.1 - 0.028 14.7 0.5 7.1 7.0 0.0 3.3 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Ufm1 PF03671.14 GBG76137.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein DUF659 PF04937.15 GBG76138.1 - 7.9e-15 55.0 0.1 1.6e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG76138.1 - 1.5e-07 31.6 0.0 5.4e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG76138.1 - 0.15 11.9 0.0 0.48 10.2 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG76139.1 - 3e-74 245.4 0.0 1.7e-23 82.6 0.0 4.7 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76139.1 - 2.7e-61 204.4 0.0 8.9e-21 74.2 0.0 5.2 5 0 0 5 5 5 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76139.1 - 2e-49 168.1 0.2 4.2e-25 88.6 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76139.1 - 1.8e-31 108.0 1.7 1.9e-16 59.9 0.6 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG76139.1 - 1e-27 96.7 1.5 2.5e-14 53.5 0.0 4.3 5 0 0 5 5 4 2 Integrase core domain gag-asp_proteas PF13975.6 GBG76139.1 - 1e-05 26.0 0.0 2.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76139.1 - 1.3e-05 25.8 0.0 3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG76139.1 - 8.4e-05 22.4 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76139.1 - 0.00044 20.0 0.0 0.00097 18.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 GBG76139.1 - 0.00096 18.9 0.0 0.024 14.4 0.0 3.3 3 0 0 3 3 3 1 Integrase core domain Retrotrans_gag PF03732.17 GBG76139.1 - 0.0035 17.6 0.1 0.023 15.0 0.1 2.5 1 0 0 1 1 1 1 Retrotransposon gag protein Trans_reg_C PF00486.28 GBG76139.1 - 0.11 12.6 1.2 3.9 7.6 0.1 2.8 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Phage_tail_2 PF06199.11 GBG76140.1 - 0.029 14.5 0.0 0.11 12.6 0.0 2.0 2 1 1 3 3 3 0 Phage tail tube protein zf-CCHC_4 PF14392.6 GBG76140.1 - 0.093 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG76141.1 - 1.8e-29 102.8 0.0 2.9e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76141.1 - 0.00023 21.0 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A3 PF02160.15 GBG76141.1 - 0.028 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) NIF PF03031.18 GBG76141.1 - 0.066 13.0 0.0 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase IL11 PF07400.11 GBG76141.1 - 0.24 11.0 0.8 0.6 9.7 0.8 1.7 1 0 0 1 1 1 0 Interleukin 11 RT_RNaseH_2 PF17919.1 GBG76143.1 - 8e-29 99.6 0.0 2e-28 98.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76143.1 - 1.8e-27 95.7 0.0 4.8e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76143.1 - 3.7e-13 49.4 0.1 7.8e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG76143.1 - 1.7e-07 31.1 0.0 3.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76143.1 - 1.3e-06 28.9 0.0 2.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG76143.1 - 5.2e-05 22.9 0.3 0.048 13.2 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG76143.1 - 0.00021 21.8 0.0 0.00071 20.1 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG76143.1 - 0.0025 17.6 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG76143.1 - 0.028 14.2 0.0 0.076 12.8 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG76143.1 - 0.15 12.3 0.0 0.92 9.8 0.0 2.4 2 0 0 2 2 2 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG76144.1 - 8.3e-17 61.4 0.0 6.7e-16 58.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76144.1 - 1.2e-16 60.6 0.0 3.9e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76144.1 - 1.9e-09 37.4 0.0 3.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cbl_N PF02262.16 GBG76144.1 - 0.019 15.0 0.1 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 TAFII28 PF04719.14 GBG76144.1 - 0.14 12.3 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region RVT_1 PF00078.27 GBG76145.1 - 4.3e-32 111.4 0.2 6.9e-19 68.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76145.1 - 1.2e-26 92.6 2.0 2.4e-15 56.4 0.0 4.3 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76145.1 - 1.8e-24 86.0 0.0 5.6e-13 49.1 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76145.1 - 1e-15 57.5 0.4 2.9e-15 56.1 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76145.1 - 1.3e-08 35.1 0.0 4.2e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG76145.1 - 2.8e-06 27.1 0.0 6.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG76145.1 - 6e-06 26.8 0.0 3.2e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76145.1 - 1e-05 26.0 0.0 2.9e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG76145.1 - 0.00017 21.4 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG76145.1 - 0.0013 18.9 9.5 0.92 9.8 0.0 5.7 5 1 1 6 6 6 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG76145.1 - 0.0042 17.3 2.2 0.018 15.2 0.3 2.6 2 0 0 2 2 2 1 H2C2 zinc finger DUF1676 PF07898.13 GBG76146.1 - 0.087 12.9 0.1 0.12 12.5 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) RNase_J_C PF17770.1 GBG76147.1 - 0.28 12.3 3.2 30 5.8 0.0 3.9 3 1 1 4 4 4 0 Ribonuclease J C-terminal domain Pectinesterase PF01095.19 GBG76149.1 - 8.4e-61 205.3 0.3 1e-60 205.0 0.3 1.0 1 0 0 1 1 1 1 Pectinesterase Chondroitinas_B PF14592.6 GBG76149.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Chondroitinase B DUF3439 PF11921.8 GBG76149.1 - 4.8 7.2 15.1 0.66 10.0 9.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pectinesterase PF01095.19 GBG76150.1 - 1.2e-61 208.1 1.1 1.4e-61 207.8 1.1 1.1 1 0 0 1 1 1 1 Pectinesterase DUF4266 PF14086.6 GBG76151.1 - 0.13 13.2 2.1 0.53 11.3 2.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Shugoshin_N PF07558.11 GBG76151.1 - 0.2 11.6 5.8 2.6 8.0 0.0 4.0 4 1 1 5 5 5 0 Shugoshin N-terminal coiled-coil region ZapB PF06005.12 GBG76151.1 - 0.23 11.9 34.5 1.1 9.8 2.1 5.8 3 1 1 4 4 4 0 Cell division protein ZapB Filament PF00038.21 GBG76151.1 - 2.3 7.7 24.6 1.1 8.7 17.9 2.8 1 1 1 2 2 2 0 Intermediate filament protein PCRF PF03462.18 GBG76151.1 - 6.7 6.5 18.6 4.6 7.1 3.4 3.1 2 1 1 3 3 3 0 PCRF domain Pectinesterase PF01095.19 GBG76152.1 - 8.5e-61 205.3 1.0 1e-60 205.0 1.0 1.1 1 0 0 1 1 1 1 Pectinesterase VWA_3 PF13768.6 GBG76153.1 - 2.2e-16 60.1 0.0 3.8e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GBG76153.1 - 7.8e-10 39.4 0.0 1.9e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GBG76153.1 - 3.1e-07 30.8 0.0 5.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 GBG76153.1 - 0.00064 19.2 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Ost5 PF05251.12 GBG76153.1 - 0.035 14.4 0.1 0.083 13.2 0.1 1.6 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 vWA-TerF-like PF10138.9 GBG76153.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus InPase PF18823.1 GBG76153.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Inorganic Pyrophosphatase DUF5308 PF17233.2 GBG76154.1 - 2.3 8.4 5.4 2.7 8.2 5.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Nop14 PF04147.12 GBG76155.1 - 0.012 13.9 51.2 0.016 13.5 51.2 1.2 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 GBG76155.1 - 0.062 13.5 22.8 0.086 13.0 22.8 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SDA1 PF05285.12 GBG76155.1 - 0.31 10.4 57.3 0.4 10.1 57.3 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG76155.1 - 0.55 9.5 50.6 0.63 9.3 50.6 1.1 1 0 0 1 1 1 0 BUD22 DUF4045 PF13254.6 GBG76155.1 - 0.84 9.2 20.1 0.94 9.1 20.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 GBG76155.1 - 4.6 6.2 20.5 5.2 6.0 20.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 GBG76155.1 - 5.3 5.7 30.3 6.2 5.5 30.3 1.1 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 GBG76155.1 - 9 5.3 28.6 11 5.0 28.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AAA_12 PF13087.6 GBG76156.1 - 5.2e-42 143.7 0.0 8.9e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG76156.1 - 5.7e-29 101.7 0.2 1.3e-13 51.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GBG76156.1 - 1.9e-08 34.8 0.0 4.5e-06 27.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GBG76156.1 - 5.4e-08 32.8 0.2 0.00017 21.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 GBG76156.1 - 3.2e-05 23.4 2.0 0.016 14.4 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 GBG76156.1 - 0.00013 21.1 0.1 0.0008 18.5 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein UvrD-helicase PF00580.21 GBG76156.1 - 0.00074 19.1 0.0 0.0038 16.8 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 GBG76156.1 - 0.0008 18.9 0.1 0.0018 17.8 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.6 GBG76156.1 - 0.004 17.5 0.1 0.021 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ResIII PF04851.15 GBG76156.1 - 0.0075 16.3 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 GBG76156.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 GBG76156.1 - 0.036 14.4 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 GBG76156.1 - 0.046 13.5 1.3 0.23 11.2 1.3 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 GBG76156.1 - 0.05 13.0 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 GBG76156.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 GBG76156.1 - 0.1 12.6 0.1 0.34 10.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GBG76156.1 - 0.17 12.3 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RVT_1 PF00078.27 GBG76158.1 - 2.2e-31 109.1 0.1 3.5e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76158.1 - 1.3e-12 47.6 0.2 3.6e-12 46.2 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76158.1 - 7.1e-08 32.7 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG76158.1 - 0.021 14.8 2.0 0.06 13.3 2.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG76158.1 - 0.034 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG76160.1 - 3.1e-25 88.1 0.0 6.7e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76160.1 - 1.5e-21 76.6 0.0 2.9e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76160.1 - 6.6e-20 71.6 0.1 1.2e-19 70.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0262 PF06793.12 GBG76161.1 - 0.05 13.7 0.1 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) PvlArgDC PF01862.16 GBG76161.1 - 6.2 6.6 7.6 1.6 8.5 0.2 2.5 2 1 1 3 3 3 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) DUF3527 PF12043.8 GBG76162.1 - 0.0057 16.3 2.9 0.0057 16.3 2.9 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3527) RVT_1 PF00078.27 GBG76163.1 - 8.3e-35 120.3 0.0 1.2e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76163.1 - 3e-25 88.2 0.0 7.8e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76163.1 - 7.2e-14 52.0 0.0 1.6e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG76164.1 - 0.027 14.4 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG76164.1 - 0.063 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DUF1564 PF07600.11 GBG76164.1 - 0.14 11.8 0.1 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG76165.1 - 2.1e-28 99.4 0.0 3.1e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76165.1 - 1.1e-16 60.6 0.0 2.4e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76165.1 - 1.3e-05 25.4 0.0 2.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Methyltransf_1N PF02870.15 GBG76166.1 - 0.00024 21.9 7.8 11 6.9 0.1 6.6 3 2 4 7 7 7 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain PapC_C PF13953.6 GBG76166.1 - 0.0028 17.4 30.1 1.3 8.9 1.4 7.7 1 1 8 9 9 9 3 PapC C-terminal domain FBA_3 PF08268.12 GBG76166.1 - 0.12 12.4 8.3 8 6.4 0.1 4.3 1 1 4 5 5 5 0 F-box associated domain RTA1 PF04479.13 GBG76166.1 - 0.39 10.3 10.9 70 2.9 0.1 6.5 1 1 7 8 8 8 0 RTA1 like protein ImpE PF07024.13 GBG76166.1 - 2.9 8.0 11.1 44 4.2 0.1 5.2 1 1 4 7 7 7 0 ImpE protein SH3_19 PF18597.1 GBG76166.1 - 8.5 6.3 32.3 19 5.2 0.1 8.6 9 0 0 9 9 9 0 Myosin X N-terminal SH3 domain ATP_transf PF09830.9 GBG76166.1 - 9.6 6.4 15.0 62 3.8 0.1 6.4 1 1 6 8 8 8 0 ATP adenylyltransferase Ku_N PF03731.15 GBG76167.1 - 0.085 12.6 0.1 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain DUF2730 PF10805.8 GBG76167.1 - 0.14 12.3 0.2 0.54 10.4 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) RT_RNaseH_2 PF17919.1 GBG76168.1 - 3.4e-30 104.0 0.0 7.3e-30 103.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76168.1 - 1.2e-27 96.2 0.3 3.2e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76168.1 - 2.7e-18 65.8 0.1 6.2e-18 64.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76168.1 - 9.9e-12 44.8 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76168.1 - 1e-11 45.1 0.4 3.8e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Myosin_TH1 PF06017.13 GBG76168.1 - 0.052 13.2 0.2 0.095 12.4 0.2 1.4 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Rrn6 PF10214.9 GBG76168.1 - 2.1 6.7 8.5 3 6.2 8.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor rve PF00665.26 GBG76169.1 - 4.6e-11 42.9 0.0 1.4e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG76169.1 - 0.027 14.2 0.0 0.078 12.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain ACT_3 PF10000.9 GBG76169.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 ACT domain rve PF00665.26 GBG76170.1 - 2.9e-11 43.6 0.0 5.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG76170.1 - 0.012 15.4 0.0 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain DUF659 PF04937.15 GBG76171.1 - 2.4e-20 72.9 0.0 7.8e-20 71.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG76171.1 - 8.1e-14 51.8 0.0 3.3e-13 49.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG76171.1 - 0.00019 21.1 0.0 0.00051 19.8 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1564 PF07600.11 GBG76171.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) rve PF00665.26 GBG76172.1 - 2.9e-15 56.5 0.0 5.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG76172.1 - 6.1e-15 55.1 0.1 2.3e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 GBG76172.1 - 0.0022 17.7 0.0 0.0065 16.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG76172.1 - 0.0098 16.1 0.2 0.02 15.1 0.2 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG76173.1 - 9.7e-36 123.4 0.0 1.7e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76173.1 - 4e-29 100.6 0.0 1.1e-28 99.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76173.1 - 1.1e-28 99.6 0.0 2.7e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RNA_pol_3_Rpc31 PF11705.8 GBG76173.1 - 0.5 10.6 9.1 1.2 9.4 9.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Phage_GPO PF05929.11 GBG76173.1 - 1.1 8.8 8.7 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase NARP1 PF12569.8 GBG76173.1 - 2.2 7.1 14.8 4.2 6.2 14.8 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 VIR_N PF15912.5 GBG76173.1 - 4.8 6.7 5.8 7.9 6.0 5.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Plk4_PB1 PF18190.1 GBG76174.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 RT_RNaseH_2 PF17919.1 GBG76175.1 - 4.2e-25 87.7 0.0 9.5e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76175.1 - 1.2e-24 86.6 0.0 2.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76175.1 - 7.4e-13 48.7 0.0 3.8e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG76175.1 - 0.003 17.8 4.7 0.0081 16.4 0.0 4.1 5 0 0 5 5 5 1 Retrotransposon gag protein rve_3 PF13683.6 GBG76175.1 - 0.0038 17.0 0.0 0.016 15.0 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain FAM76 PF16046.5 GBG76175.1 - 0.053 12.9 3.7 0.1 11.9 3.7 1.4 1 0 0 1 1 1 0 FAM76 protein RT_RNaseH PF17917.1 GBG76176.1 - 4.1e-23 81.7 0.0 8.6e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76176.1 - 1.2e-21 76.6 0.0 2.3e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76176.1 - 8e-10 38.7 1.2 1.5e-09 37.8 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG76176.1 - 1.3e-07 32.2 0.1 3.1e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76176.1 - 1.7e-05 25.3 0.3 3.9e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG76176.1 - 0.16 11.7 0.9 0.34 10.7 0.9 1.4 1 0 0 1 1 1 0 Aspartyl protease Pep_deformylase PF01327.21 GBG76176.1 - 0.45 10.1 2.6 0.91 9.1 2.6 1.4 1 0 0 1 1 1 0 Polypeptide deformylase zf-CCHC PF00098.23 GBG76178.1 - 0.0058 16.6 2.1 0.013 15.6 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle CCDC32 PF14989.6 GBG76178.1 - 0.99 9.4 6.9 0.077 13.0 1.8 1.7 2 1 0 2 2 2 0 Coiled-coil domain containing 32 zf-CCHC_2 PF13696.6 GBG76178.1 - 3 7.7 6.9 0.67 9.8 3.1 1.8 2 0 0 2 2 2 0 Zinc knuckle CDC27 PF09507.10 GBG76179.1 - 5.1 6.4 32.5 6.5 6.0 32.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PCEMA1 PF07418.11 GBG76179.1 - 7.3 6.0 16.6 10 5.5 16.6 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF2385 PF09539.10 GBG76180.1 - 0.034 14.6 0.3 1 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) zf-CCHC_2 PF13696.6 GBG76180.1 - 8.9 6.2 6.5 14 5.6 6.5 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG76181.1 - 6.4e-29 101.0 0.1 9.8e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76181.1 - 5.2e-16 58.5 0.2 1.4e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG76181.1 - 1.4e-05 25.2 0.0 3.9e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 H2C2 zinc finger rve PF00665.26 GBG76181.1 - 0.00029 21.0 0.0 0.00068 19.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG76182.1 - 1.9e-27 96.2 0.8 4.8e-27 94.9 0.1 2.0 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG76182.1 - 2.2e-05 24.6 12.4 0.00011 22.4 0.2 4.1 5 0 0 5 5 5 2 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG76182.1 - 0.0064 17.1 3.8 0.0064 17.1 3.8 3.5 3 1 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 LMBR1 PF04791.16 GBG76182.1 - 0.52 9.2 3.3 0.9 8.4 2.6 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein FUSC PF04632.12 GBG76182.1 - 5.3 5.5 16.6 9.1 4.7 16.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Use1 PF09753.9 GBG76183.1 - 0.013 15.2 7.1 0.021 14.6 7.1 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF4404 PF14357.6 GBG76183.1 - 0.062 13.9 0.3 0.062 13.9 0.3 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) Plexin_cytopl PF08337.12 GBG76183.1 - 0.071 11.8 1.8 0.096 11.3 1.8 1.1 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Spc7 PF08317.11 GBG76183.1 - 0.54 9.1 10.3 2.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4288 PF14119.6 GBG76183.1 - 0.86 10.0 4.9 1.6 9.1 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) DUF659 PF04937.15 GBG76184.1 - 4.3e-34 117.6 0.0 6.2e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CAP59_mtransfer PF11735.8 GBG76184.1 - 0.037 13.7 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 UBA PF00627.31 GBG76188.1 - 7.5e-05 22.5 0.3 0.021 14.7 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain DUF4461 PF14688.6 GBG76189.1 - 1.4e-38 133.4 0.0 2.6e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.6 GBG76189.1 - 3.6e-14 52.8 0.3 8.2e-14 51.6 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DnaJ PF00226.31 GBG76189.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 DnaJ domain Dimer_Tnp_hAT PF05699.14 GBG76190.1 - 0.0021 17.8 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HBB PF06777.11 GBG76191.1 - 0.015 14.9 0.7 0.12 12.1 0.7 2.1 1 1 0 1 1 1 0 Helical and beta-bridge domain DUF919 PF06034.11 GBG76191.1 - 0.075 12.9 1.3 0.2 11.5 1.3 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) PET117 PF15786.5 GBG76191.1 - 5.4 7.3 6.8 20 5.5 5.9 2.3 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial DUF659 PF04937.15 GBG76192.1 - 8.8e-29 100.3 0.0 1.5e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG76192.1 - 4.3e-09 36.0 0.3 1.3e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF3306 PF11748.8 GBG76192.1 - 0.095 13.6 1.0 0.28 12.0 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Bclt PF15318.6 GBG76193.1 - 0.015 15.2 8.5 0.1 12.4 0.3 2.3 1 1 1 2 2 2 0 Putative Bcl-2 like protein of testis SID-1_RNA_chan PF13965.6 GBG76193.1 - 0.5 8.7 0.6 0.43 8.9 0.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CobT PF06213.12 GBG76193.1 - 0.7 9.2 23.3 0.78 9.1 23.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BNIP2 PF12496.8 GBG76193.1 - 3.1 8.3 14.3 4.9 7.6 14.3 1.5 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SDA1 PF05285.12 GBG76193.1 - 6.7 6.0 24.8 7.2 5.9 24.8 1.1 1 0 0 1 1 1 0 SDA1 Nup54 PF13874.6 GBG76194.1 - 9.7e-28 97.0 4.0 9.7e-28 97.0 4.0 2.2 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 CTD PF12815.7 GBG76194.1 - 1.3e-10 41.7 12.4 8e-06 26.3 12.4 3.3 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Nucleoporin_FG PF13634.6 GBG76194.1 - 0.076 13.9 68.3 31 5.5 19.2 3.6 1 1 1 2 2 2 0 Nucleoporin FG repeat region Nup54_C PF18437.1 GBG76194.1 - 0.083 12.8 0.2 0.083 12.8 0.2 2.1 3 0 0 3 3 3 0 Nup54 C-terminal interacting domain PRTP PF01366.18 GBG76195.1 - 1.1 7.3 9.0 1.4 6.8 9.0 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein BAF1_ABF1 PF04684.13 GBG76195.1 - 6.4 5.7 17.6 8.4 5.3 17.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RT_RNaseH_2 PF17919.1 GBG76196.1 - 2.6e-31 107.6 0.0 2e-15 56.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76196.1 - 6.9e-29 100.9 0.0 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76196.1 - 8e-29 100.0 0.0 1.9e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG76196.1 - 0.012 16.2 0.0 0.033 14.8 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC_6 PF15288.6 GBG76197.1 - 0.07 13.0 0.4 0.17 11.8 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG76197.1 - 0.15 12.2 4.9 0.23 11.6 4.9 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG76198.1 - 3.7e-13 49.5 0.0 7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG76198.1 - 1.6e-10 40.7 0.0 4e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG76198.1 - 8e-09 35.7 0.0 2.1e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Response_reg PF00072.24 GBG76199.1 - 6e-16 58.6 0.2 2.9e-11 43.5 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain OrfB_IS605 PF01385.19 GBG76199.1 - 2.9 8.1 5.2 6.3 7.1 5.2 1.5 1 0 0 1 1 1 0 Probable transposase Abhydrolase_1 PF00561.20 GBG76200.1 - 1.9e-14 53.9 0.0 1.2e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG76200.1 - 5.7e-08 32.3 0.0 2.1e-07 30.5 0.0 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 GBG76200.1 - 0.038 13.3 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LON_substr_bdg PF02190.16 GBG76201.1 - 8.3e-23 81.4 0.0 2.2e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 GBG76201.1 - 1.5e-07 31.6 0.0 2.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CDC45 PF02724.14 GBG76201.1 - 6.9 4.8 8.4 12 4.0 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG76201.1 - 7.9 5.7 9.4 14 4.9 9.4 1.4 1 0 0 1 1 1 0 NOA36 protein DUF1677 PF07911.13 GBG76202.1 - 0.8 10.1 6.0 13 6.3 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) Peptidase_C54 PF03416.19 GBG76203.1 - 1.3e-63 215.0 0.0 1.7e-63 214.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 WD40 PF00400.32 GBG76204.1 - 1.3e-06 29.0 14.0 0.016 16.0 0.2 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat RVT_1 PF00078.27 GBG76205.1 - 3.8e-13 49.5 0.3 1e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76205.1 - 1.3e-05 25.7 0.0 0.00011 22.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76205.1 - 2.3e-05 24.9 0.0 7.3e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG76205.1 - 5.5e-05 23.4 3.4 0.0028 17.9 0.0 3.6 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG76205.1 - 0.0003 20.6 0.0 0.00087 19.1 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG76205.1 - 0.00079 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG76208.1 - 1.5e-16 60.6 0.0 2.4e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76208.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DA1-like PF12315.8 GBG76208.1 - 0.086 12.2 0.8 7.9 5.8 0.0 3.1 3 0 0 3 3 3 0 Protein DA1 DDHD PF02862.17 GBG76208.1 - 0.13 12.4 4.3 5 7.2 1.2 2.4 2 0 0 2 2 2 0 DDHD domain FAM60A PF15396.6 GBG76208.1 - 4 7.4 14.1 0.37 10.8 0.7 2.5 2 0 0 2 2 2 0 Protein Family FAM60A Co_AT_N PF12557.8 GBG76209.1 - 0.034 14.1 4.7 0.034 14.1 4.7 2.3 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal UPF0561 PF10573.9 GBG76209.1 - 9.1 6.4 9.2 0.2 11.8 0.9 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0561 zf-CCHC PF00098.23 GBG76211.1 - 0.005 16.9 1.1 0.0098 15.9 0.2 1.9 2 0 0 2 2 2 1 Zinc knuckle SDA1 PF05285.12 GBG76211.1 - 0.96 8.8 5.7 1.2 8.4 5.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG76211.1 - 1.4 7.1 4.3 1.6 6.9 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG76211.1 - 1.8 6.7 5.3 2.6 6.3 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG76212.1 - 4.3e-26 90.9 0.0 7.4e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76212.1 - 5.2e-25 87.8 0.0 1.1e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76212.1 - 2.4e-11 43.6 0.1 3.7e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG76212.1 - 1.7 6.8 7.7 2.4 6.4 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG76212.1 - 3.6 5.7 10.3 4.5 5.3 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 GBG76213.1 - 3.2e-33 115.2 0.0 8.3e-33 113.9 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76213.1 - 1.5e-31 109.7 0.0 4.4e-31 108.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GBG76213.1 - 0.0024 17.8 0.3 0.02 14.8 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 GBG76213.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family TFIIF_alpha PF05793.12 GBG76213.1 - 0.2 10.2 17.2 0.28 9.7 17.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PTPRCAP PF15713.5 GBG76213.1 - 0.21 11.9 15.2 0.35 11.2 15.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated VEGFR-2_TMD PF17988.1 GBG76213.1 - 0.41 10.1 2.5 0.75 9.3 2.5 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Presenilin PF01080.17 GBG76213.1 - 2.5 6.7 8.1 4.7 5.9 8.1 1.3 1 0 0 1 1 1 0 Presenilin SspB PF04386.13 GBG76213.1 - 3.8 7.4 6.2 12 5.7 5.6 2.1 2 0 0 2 2 2 0 Stringent starvation protein B CDC45 PF02724.14 GBG76213.1 - 4.6 5.4 15.3 6.4 4.9 15.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 GBG76213.1 - 5.8 5.6 7.1 7.8 5.2 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PRP38_assoc PF12871.7 GBG76213.1 - 8.1 7.1 20.8 15 6.2 20.8 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Merozoite_SPAM PF07133.11 GBG76213.1 - 8.2 6.4 21.5 12 5.8 21.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PSP PF04046.16 GBG76214.1 - 3e-16 59.0 0.4 6.9e-16 57.9 0.4 1.6 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.23 GBG76214.1 - 0.0034 17.4 8.0 0.031 14.4 2.6 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 GBG76214.1 - 0.013 15.3 4.1 0.54 10.1 0.2 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG76214.1 - 0.28 10.9 1.8 0.53 10.1 0.4 2.0 2 0 0 2 2 2 0 Zinc knuckle PSP PF04046.16 GBG76215.1 - 3e-16 59.0 0.4 6.7e-16 57.9 0.4 1.6 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.23 GBG76215.1 - 0.0033 17.4 8.0 0.031 14.4 2.6 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 GBG76215.1 - 0.013 15.3 4.1 0.53 10.2 0.2 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG76215.1 - 0.28 11.0 1.8 0.52 10.1 0.4 2.0 2 0 0 2 2 2 0 Zinc knuckle DUF4360 PF14273.6 GBG76216.1 - 2.9e-106 353.0 1.6 3.6e-56 189.8 1.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4360) NPCBM_assoc PF10633.9 GBG76216.1 - 0.014 15.6 0.0 5.5 7.3 0.0 2.6 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SR-25 PF10500.9 GBG76216.1 - 1.6 8.3 9.7 2.7 7.5 9.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Beta_helix PF13229.6 GBG76217.1 - 0.0016 18.3 3.7 0.0029 17.5 3.7 1.4 1 0 0 1 1 1 1 Right handed beta helix region Dimer_Tnp_hAT PF05699.14 GBG76217.1 - 0.073 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Glyco_transf_20 PF00982.21 GBG76219.1 - 5.9e-87 292.3 0.0 6.6e-46 157.0 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase family 20 CDC45 PF02724.14 GBG76219.1 - 0.00038 18.9 22.0 0.0005 18.5 22.0 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GBG76219.1 - 0.61 9.5 38.3 0.83 9.0 38.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG76219.1 - 0.82 7.8 37.7 1.1 7.3 37.7 1.0 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 GBG76219.1 - 1.8 8.7 38.3 3.3 7.7 38.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG76219.1 - 2.4 7.4 34.1 3.2 7.0 34.1 1.1 1 0 0 1 1 1 0 BUD22 DUF4604 PF15377.6 GBG76219.1 - 9.3 6.6 32.4 18 5.7 32.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF2828 PF11443.8 GBG76220.1 - 0.0054 14.9 6.2 0.0075 14.4 6.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) RR_TM4-6 PF06459.12 GBG76220.1 - 0.1 12.4 8.7 0.14 12.0 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 GBG76220.1 - 0.1 12.0 2.8 0.14 11.6 2.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4366 PF14283.6 GBG76220.1 - 0.11 12.6 1.0 0.16 12.0 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Eapp_C PF10238.9 GBG76220.1 - 0.27 11.3 4.4 0.65 10.1 4.4 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein Presenilin PF01080.17 GBG76220.1 - 1 8.1 8.8 1.5 7.5 8.8 1.2 1 0 0 1 1 1 0 Presenilin IDO PF01231.18 GBG76220.1 - 2.4 6.9 5.4 3.2 6.4 5.4 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase Connexin PF00029.19 GBG76220.1 - 2.8 7.7 7.4 3.7 7.2 7.4 1.2 1 0 0 1 1 1 0 Connexin DUF4741 PF15897.5 GBG76220.1 - 3.8 7.3 7.0 7.6 6.3 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) Paf1 PF03985.13 GBG76220.1 - 6.4 5.7 21.1 8.9 5.2 21.1 1.1 1 0 0 1 1 1 0 Paf1 Glyco_transf_20 PF00982.21 GBG76221.1 - 1.1e-166 555.3 0.0 1.4e-166 554.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GBG76221.1 - 1.1e-65 221.0 0.0 4.6e-64 215.7 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.12 GBG76221.1 - 0.0016 18.2 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF659 PF04937.15 GBG76222.1 - 3.9e-32 111.2 0.1 8.6e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG76222.1 - 0.00045 20.0 0.9 0.0012 18.6 0.9 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Dapper PF15268.6 GBG76222.1 - 0.56 9.0 37.8 0.78 8.5 37.8 1.1 1 0 0 1 1 1 0 Dapper Caldesmon PF02029.15 GBG76222.1 - 5.2 5.7 46.5 8.2 5.1 46.5 1.2 1 0 0 1 1 1 0 Caldesmon GREB1 PF15782.5 GBG76222.1 - 7.4 3.5 30.3 9.9 3.1 30.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer gag-asp_proteas PF13975.6 GBG76223.1 - 1.9e-07 31.5 0.3 5.3e-07 30.1 0.1 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76223.1 - 1.9e-05 25.2 0.1 5.8e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG76223.1 - 0.00018 21.3 0.1 0.00029 20.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76223.1 - 0.0042 16.9 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG76223.1 - 0.13 11.9 0.2 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Integrase_H2C2 PF17921.1 GBG76224.1 - 6.6e-15 55.0 1.4 2e-14 53.4 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG76224.1 - 6.4e-12 45.7 0.2 2e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG76224.1 - 1.1e-11 44.5 0.0 2.2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG76224.1 - 0.00013 22.1 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Pkinase PF00069.25 GBG76225.1 - 5e-07 29.4 0.0 5.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76225.1 - 0.0005 19.4 0.0 0.00087 18.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 GBG76226.1 - 1.1e-09 38.1 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76226.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease PAS_3 PF08447.12 GBG76226.1 - 0.15 12.3 0.0 4.2 7.7 0.0 3.0 3 0 0 3 3 3 0 PAS fold LRR_4 PF12799.7 GBG76227.1 - 2.9e-07 30.7 2.1 4.6e-07 30.1 2.1 1.3 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG76227.1 - 2.7e-05 23.8 3.2 4.2e-05 23.2 3.2 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 GBG76227.1 - 0.00012 22.1 1.7 0.19 12.4 0.2 2.8 2 0 0 2 2 2 2 Leucine Rich Repeat Miga PF10265.9 GBG76227.1 - 2 7.3 7.9 2.7 6.9 7.9 1.0 1 0 0 1 1 1 0 Mitoguardin Neur_chan_memb PF02932.16 GBG76227.1 - 3.6 7.6 6.3 5.4 7.0 6.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 GBG76227.1 - 9.4 5.9 6.5 25 4.5 6.5 1.7 1 1 0 1 1 1 0 Connexin Malectin_like PF12819.7 GBG76228.1 - 1.1e-12 47.8 0.0 2.3e-12 46.8 0.0 1.5 2 0 0 2 2 2 1 Malectin-like domain Malectin PF11721.8 GBG76228.1 - 7.7e-08 32.6 0.0 0.0026 17.9 0.0 2.4 2 0 0 2 2 2 2 Malectin domain Pkinase PF00069.25 GBG76229.1 - 1.5e-41 142.6 0.0 2.3e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76229.1 - 1.1e-27 97.0 0.0 1.7e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG76229.1 - 0.00075 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GBG76229.1 - 0.077 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 GBG76230.1 - 6.1e-47 160.1 0.0 1e-46 159.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76230.1 - 1.3e-44 152.6 0.0 1.6e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PIP49_C PF12260.8 GBG76230.1 - 0.008 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 APH PF01636.23 GBG76230.1 - 0.05 13.5 0.2 0.084 12.8 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GBG76232.1 - 1.9e-48 165.0 0.0 2.8e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76232.1 - 2.1e-45 155.2 0.0 2.6e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PIP49_C PF12260.8 GBG76232.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 GBG76232.1 - 0.04 12.7 1.0 0.053 12.3 1.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GBG76232.1 - 0.065 13.1 0.1 0.1 12.5 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG76232.1 - 0.099 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RT_RNaseH_2 PF17919.1 GBG76233.1 - 1.1e-28 99.2 0.0 2.2e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76233.1 - 3.5e-26 91.5 0.0 8.7e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_M28 PF04389.17 GBG76233.1 - 6.1e-22 78.3 0.0 9.8e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 RVT_1 PF00078.27 GBG76233.1 - 2.8e-12 46.6 0.0 4.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG76233.1 - 1.3e-05 25.8 0.4 3e-05 24.6 0.4 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Peptidase_M20 PF01546.28 GBG76233.1 - 0.031 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 CDC45 PF02724.14 GBG76233.1 - 3.7 5.7 14.3 8.1 4.6 14.3 1.5 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG76233.1 - 4.4 6.6 24.6 8.5 5.7 24.6 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG76233.1 - 5.8 6.1 22.2 11 5.2 22.2 1.3 1 0 0 1 1 1 0 BUD22 RT_RNaseH_2 PF17919.1 GBG76234.1 - 4e-31 107.0 0.0 9.6e-31 105.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76234.1 - 2.3e-30 105.0 0.0 5.8e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76234.1 - 0.00033 20.7 0.0 0.00071 19.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76234.1 - 0.021 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG76236.1 - 1.2e-35 123.0 0.1 2.3e-35 122.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76236.1 - 2.4e-29 101.7 0.0 6.6e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76236.1 - 4.7e-28 97.2 0.2 2e-27 95.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76236.1 - 3.9e-14 52.5 0.1 1.1e-13 51.0 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76236.1 - 0.00024 21.3 0.1 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG76236.1 - 0.00074 19.7 0.0 0.0022 18.2 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG76237.1 - 1.6e-32 111.5 0.0 3.9e-32 110.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76237.1 - 1.2e-28 99.4 0.2 6.1e-28 97.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76237.1 - 8.8e-23 81.0 0.0 1.8e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76237.1 - 3e-18 65.6 0.3 1e-17 64.0 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG76237.1 - 4e-11 43.1 0.0 1.1e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Exonuc_VII_L PF02601.15 GBG76237.1 - 2.9 7.4 9.0 5.5 6.5 9.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit HrpB7 PF09486.10 GBG76237.1 - 6.6 7.1 14.5 15 5.9 14.5 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Phage_GPO PF05929.11 GBG76237.1 - 6.6 6.3 6.8 5 6.7 0.1 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Snapin_Pallidin PF14712.6 GBG76237.1 - 9.1 6.8 11.2 0.97 9.9 0.2 2.8 1 1 0 2 2 2 0 Snapin/Pallidin Myb_DNA-bind_4 PF13837.6 GBG76240.1 - 3.3e-06 27.4 4.5 6.2e-06 26.5 4.5 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG76240.1 - 0.92 9.8 4.2 2.6 8.3 4.2 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain Lipase_3 PF01764.25 GBG76243.1 - 1.4e-30 106.0 0.0 6.1e-30 104.0 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Myb_DNA-bind_4 PF13837.6 GBG76243.1 - 1.5e-08 34.9 2.2 4.5e-08 33.4 2.2 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Abhydrolase_6 PF12697.7 GBG76243.1 - 0.0022 18.6 0.9 0.0022 18.6 0.9 4.0 3 1 1 4 4 4 1 Alpha/beta hydrolase family LapA_dom PF06305.11 GBG76243.1 - 0.0039 17.0 0.1 0.0077 16.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain MADF_DNA_bdg PF10545.9 GBG76243.1 - 0.0085 16.4 0.9 0.031 14.6 0.3 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG76243.1 - 0.011 15.8 0.3 0.032 14.3 0.3 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2974 PF11187.8 GBG76243.1 - 0.023 14.3 0.0 0.94 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 GBG76243.1 - 0.088 12.5 0.3 0.21 11.3 0.1 1.6 2 0 0 2 2 2 0 PGAP1-like protein DDE_Tnp_4 PF13359.6 GBG76244.1 - 6.1e-29 100.7 0.0 7.9e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76244.1 - 2.2e-12 47.0 0.0 3.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG76244.1 - 0.00054 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Transposase DDE domain zf-CCHC PF00098.23 GBG76246.1 - 0.24 11.6 7.7 0.18 12.0 1.2 2.4 2 0 0 2 2 2 0 Zinc knuckle FMO-like PF00743.19 GBG76247.1 - 2.1e-56 191.4 0.0 2.5e-19 69.1 0.0 4.0 4 0 0 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GBG76247.1 - 2.3e-15 56.6 0.0 7.9e-08 31.9 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG76247.1 - 5.3e-15 55.5 0.0 6.5e-08 32.2 0.0 3.9 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GBG76247.1 - 6.2e-10 39.2 0.2 6.2e-10 39.2 0.2 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GBG76247.1 - 1.3e-07 31.3 1.1 3.5e-06 26.6 0.1 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 GBG76247.1 - 5.5e-07 30.0 2.3 0.00015 22.2 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GBG76247.1 - 1.6e-06 27.5 0.1 1.6e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 GBG76247.1 - 1.9e-06 28.0 1.0 0.00014 21.9 0.3 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 GBG76247.1 - 6.5e-06 25.5 0.2 0.027 13.6 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 GBG76247.1 - 7.3e-06 24.9 0.3 1.6e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 GBG76247.1 - 2.3e-05 24.2 12.4 2.3e-05 24.2 12.4 3.5 3 1 0 3 3 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GBG76247.1 - 8.2e-05 22.0 1.7 0.00014 21.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GBG76247.1 - 0.00052 19.5 0.4 0.00052 19.5 0.4 2.1 2 1 0 3 3 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GBG76247.1 - 0.0015 17.9 1.9 0.054 12.8 0.0 2.6 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GBG76247.1 - 0.0021 17.4 0.7 0.0038 16.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 GBG76247.1 - 0.0074 15.5 4.4 0.32 10.1 0.1 3.8 4 1 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 GBG76247.1 - 0.013 15.4 1.0 1.2 9.0 0.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 GBG76247.1 - 0.017 14.8 1.5 0.2 11.3 0.0 2.9 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 GBG76247.1 - 0.023 15.1 0.1 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GBG76247.1 - 0.062 12.3 0.4 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Adeno_terminal PF02459.15 GBG76247.1 - 1 7.7 8.8 1.8 6.8 8.8 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Integrase_H2C2 PF17921.1 GBG76248.1 - 1.2e-12 47.7 2.3 3.7e-12 46.2 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG76248.1 - 3e-05 24.2 0.0 0.00015 22.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76248.1 - 0.0019 18.2 0.1 0.15 12.1 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Linker_histone PF00538.19 GBG76249.1 - 6.3e-17 61.7 0.4 2.6e-16 59.8 0.1 2.3 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF936 PF06075.12 GBG76249.1 - 4.4 6.1 37.4 5.5 5.8 37.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) ERAP1_C PF11838.8 GBG76251.1 - 8.2e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 GBG76251.1 - 0.0013 18.3 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Aldose_epim PF01263.20 GBG76254.1 - 8.7e-38 130.3 0.0 1e-37 130.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase_Tyr PF07714.17 GBG76255.1 - 4e-31 108.2 0.0 4.3e-30 104.9 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76255.1 - 8.2e-31 107.3 0.0 1e-18 67.7 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain PRIMA1 PF16101.5 GBG76255.1 - 0.0014 18.7 6.0 0.0036 17.3 6.0 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 APH PF01636.23 GBG76255.1 - 0.0021 18.0 2.0 0.17 11.7 0.0 3.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family SGL PF08450.12 GBG76255.1 - 0.064 12.8 0.0 1.2 8.7 0.0 2.4 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region ABC1 PF03109.16 GBG76255.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Pkinase_Tyr PF07714.17 GBG76256.1 - 2.5e-33 115.5 0.0 2.5e-32 112.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76256.1 - 1.2e-29 103.5 0.0 2.5e-18 66.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain ABC1 PF03109.16 GBG76256.1 - 0.061 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Myb_DNA-bind_4 PF13837.6 GBG76258.1 - 9.1e-05 22.8 0.2 0.00017 21.9 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG76258.1 - 0.0012 19.0 0.3 0.0041 17.3 0.3 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain Pkinase_Tyr PF07714.17 GBG76259.1 - 9.1e-33 113.6 0.0 2.9e-31 108.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76259.1 - 2.9e-32 112.1 0.0 3.3e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain ABC1 PF03109.16 GBG76259.1 - 0.019 15.1 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Trp_oprn_chp PF09534.10 GBG76259.1 - 0.022 14.6 0.3 0.022 14.6 0.3 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NHL PF01436.21 GBG76259.1 - 0.1 12.7 0.0 15 5.8 0.0 2.9 2 0 0 2 2 2 0 NHL repeat zf-C3HC4_2 PF13923.6 GBG76259.1 - 1.4 8.8 3.1 2.8 7.8 3.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3446 PF11928.8 GBG76261.1 - 0.23 11.8 14.1 0.58 10.5 14.1 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain Orf78 PF06024.12 GBG76262.1 - 0.0016 18.7 10.0 0.23 11.8 7.5 2.9 2 1 0 2 2 2 1 Orf78 (ac78) EVI2A PF05399.11 GBG76262.1 - 0.011 15.4 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) AUX_IAA PF02309.16 GBG76262.1 - 0.016 15.1 5.7 0.017 15.0 4.8 1.5 1 1 0 1 1 1 0 AUX/IAA family SAPS PF04499.15 GBG76262.1 - 0.018 13.9 22.2 0.021 13.6 22.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.6 GBG76262.1 - 0.022 14.4 22.0 0.026 14.2 22.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) HCO3_cotransp PF00955.21 GBG76262.1 - 0.024 13.5 0.3 0.042 12.7 0.3 1.4 1 0 0 1 1 1 0 HCO3- transporter family CSG2 PF16965.5 GBG76262.1 - 0.064 12.2 9.7 0.62 9.0 0.6 2.1 1 1 1 2 2 2 0 Ceramide synthase regulator SARAF PF06682.12 GBG76262.1 - 0.096 12.3 6.2 1.6 8.3 0.1 2.2 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Smg8_Smg9 PF10220.9 GBG76262.1 - 0.32 9.2 18.5 0.34 9.2 18.5 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Ctr PF04145.15 GBG76262.1 - 0.51 10.9 4.3 2.6 8.7 4.3 2.1 1 1 0 1 1 1 0 Ctr copper transporter family Endostatin PF06482.11 GBG76262.1 - 0.59 9.6 6.2 0.71 9.3 6.2 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin GAGA_bind PF06217.12 GBG76262.1 - 1.1 9.5 8.3 1.1 9.4 8.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF262 PF03235.14 GBG76262.1 - 1.3 9.1 16.4 2.1 8.5 16.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 SLC12 PF03522.15 GBG76262.1 - 1.8 7.5 23.1 2.5 7.0 23.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 GBG76262.1 - 2.1 7.1 18.5 2.9 6.6 18.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Connexin PF00029.19 GBG76262.1 - 4 7.1 33.9 2.9 7.6 14.9 2.3 1 1 1 2 2 2 0 Connexin DUF4407 PF14362.6 GBG76262.1 - 6.6 6.0 10.7 11 5.3 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2956 PF11169.8 GBG76262.1 - 6.9 6.9 24.6 2.6e+03 -1.4 21.8 2.7 2 1 0 2 2 1 0 Protein of unknown function (DUF2956) Flavokinase PF01687.17 GBG76263.1 - 0.043 14.1 0.3 0.09 13.1 0.3 1.5 1 0 0 1 1 1 0 Riboflavin kinase COBRA PF04833.15 GBG76264.1 - 1.1e-20 74.2 0.1 2.3e-19 69.9 0.1 2.9 2 1 0 2 2 2 1 COBRA-like protein CBM_2 PF00553.19 GBG76264.1 - 0.00029 21.1 0.2 0.68 10.3 0.0 3.4 3 0 0 3 3 3 2 Cellulose binding domain Nup88 PF10168.9 GBG76265.1 - 5.6e-16 57.5 4.4 3.7e-11 41.6 0.0 2.6 2 1 0 2 2 2 2 Nuclear pore component DUF3060 PF11259.8 GBG76265.1 - 0.042 13.5 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) Pox_Ag35 PF03286.14 GBG76265.1 - 1.6 8.5 7.1 2.9 7.7 7.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Syntaxin_2 PF14523.6 GBG76265.1 - 2.2 8.7 7.3 17 5.9 1.1 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Casc1_N PF15927.5 GBG76266.1 - 0.12 12.0 5.2 0.18 11.5 3.7 1.8 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Mago-bind PF09282.10 GBG76267.1 - 4e-15 55.4 5.0 4e-15 55.4 5.0 2.5 3 0 0 3 3 3 1 Mago binding PAP1 PF08601.10 GBG76267.1 - 0.0052 16.6 7.5 0.0063 16.3 7.5 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 TcpS PF17456.2 GBG76267.1 - 0.22 11.6 1.3 0.39 10.7 1.3 1.3 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S FAM76 PF16046.5 GBG76267.1 - 0.37 10.1 8.5 0.53 9.6 8.5 1.1 1 0 0 1 1 1 0 FAM76 protein RSN1_7TM PF02714.15 GBG76268.1 - 8.7e-37 126.9 8.7 3.8e-29 101.9 5.2 2.1 1 1 1 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate DUF1479 PF07350.12 GBG76269.1 - 0.25 10.1 3.6 0.27 9.9 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) FAM60A PF15396.6 GBG76269.1 - 1.1 9.2 6.9 1.3 9.0 6.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDC27 PF09507.10 GBG76269.1 - 1.2 8.4 18.6 1.4 8.3 18.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PA26 PF04636.13 GBG76269.1 - 2.5 6.9 8.6 2.8 6.7 8.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PBP_sp32 PF07222.12 GBG76269.1 - 2.8 7.3 13.5 3.8 6.9 13.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PIEZO PF15917.5 GBG76269.1 - 2.9 7.3 10.0 3.5 7.0 10.0 1.2 1 0 0 1 1 1 0 Piezo IncFII_repA PF02387.15 GBG76269.1 - 3.4 6.8 7.9 4.5 6.4 7.9 1.1 1 0 0 1 1 1 0 IncFII RepA protein family DUF4375 PF14300.6 GBG76269.1 - 4.1 7.7 9.1 7.2 6.9 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Asp_protease_2 PF13650.6 GBG76272.1 - 7.6e-06 26.5 0.0 2.8e-05 24.7 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76272.1 - 9.2e-05 22.9 0.0 0.00026 21.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG76272.1 - 0.00067 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG76272.1 - 0.0034 17.6 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG76272.1 - 0.0083 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG76272.1 - 0.041 14.2 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Chromo PF00385.24 GBG76272.1 - 0.044 13.7 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain DUF563 PF04577.14 GBG76273.1 - 1e-24 87.8 0.1 2.2e-24 86.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RVT_1 PF00078.27 GBG76273.1 - 1.9e-09 37.4 0.0 3.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76273.1 - 1.6 8.9 12.3 0.056 13.6 4.5 2.6 2 1 1 3 3 3 0 Integrase zinc binding domain Folate_carrier PF01770.18 GBG76274.1 - 0.18 10.5 0.0 0.18 10.5 0.0 4.3 2 1 1 3 3 3 0 Reduced folate carrier RVT_1 PF00078.27 GBG76275.1 - 1.9e-63 214.0 0.1 3.1e-32 111.9 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 GBG76275.1 - 0.00094 19.0 0.0 0.0031 17.4 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GBG76275.1 - 0.0015 18.1 0.1 0.003 17.1 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 GBG76276.1 - 4.1e-09 36.9 3.9 0.029 15.2 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.8 GBG76276.1 - 0.011 14.5 0.2 5.4 5.5 0.0 3.2 2 1 2 4 4 4 0 Nucleoporin Nup120/160 CENP-Q PF13094.6 GBG76276.1 - 0.043 14.0 3.3 0.086 13.0 3.3 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 GBG76276.1 - 0.074 13.6 8.6 0.14 12.6 8.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region AKNA PF12443.8 GBG76276.1 - 0.17 12.5 1.4 0.38 11.4 1.4 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor ZapB PF06005.12 GBG76276.1 - 0.43 11.1 7.9 0.98 9.9 6.5 2.0 2 0 0 2 2 2 0 Cell division protein ZapB Ax_dynein_light PF10211.9 GBG76276.1 - 3.1 7.7 9.6 0.58 10.1 5.8 1.6 2 0 0 2 2 2 0 Axonemal dynein light chain TSC22 PF01166.18 GBG76276.1 - 3.4 8.0 7.9 1.2 9.4 3.3 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family GrpE PF01025.19 GBG76276.1 - 4.2 7.0 8.7 1.8 8.2 5.6 1.8 2 0 0 2 2 2 0 GrpE RT_RNaseH_2 PF17919.1 GBG76277.1 - 1.3e-31 108.6 0.0 2.7e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76277.1 - 4e-31 107.4 0.0 8.1e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG76277.1 - 1.4e-07 31.4 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76277.1 - 7e-06 26.6 9.4 3.3e-05 24.4 0.0 3.7 2 1 0 3 3 3 1 Aspartyl protease RVT_1 PF00078.27 GBG76277.1 - 0.00034 20.2 0.1 0.068 12.7 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG76277.1 - 0.0021 18.6 0.1 0.0021 18.6 0.1 3.4 2 2 1 3 3 3 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG76277.1 - 0.019 14.8 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DEDD_Tnp_IS110 PF01548.17 GBG76277.1 - 0.055 13.3 0.3 0.2 11.6 0.3 1.9 1 0 0 1 1 1 0 Transposase Transferase PF02458.15 GBG76279.1 - 9.5e-62 209.0 0.0 4e-32 111.4 0.0 3.4 2 2 0 2 2 2 2 Transferase family MaoC_dehydratas PF01575.19 GBG76281.1 - 5.4e-21 74.4 0.0 1.1e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain DUF1084 PF06454.11 GBG76282.1 - 8.1e-122 405.8 10.2 9.3e-122 405.6 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF4153 PF13687.6 GBG76282.1 - 0.0054 16.4 3.8 0.0054 16.4 3.8 2.6 1 1 0 2 2 2 1 Domain of unknown function (DUF4153) RT_RNaseH PF17917.1 GBG76283.1 - 1.6e-27 95.8 0.0 4.2e-27 94.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76283.1 - 1.7e-19 69.7 0.0 5.5e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase CHD5 PF04420.14 GBG76283.1 - 0.4 10.5 2.9 0.8 9.5 2.9 1.4 1 0 0 1 1 1 0 CHD5-like protein Sin_N PF04801.13 GBG76284.1 - 5e-103 345.6 1.7 5.2e-103 345.5 0.2 1.7 3 0 0 3 3 3 1 Sin-like protein conserved region RT_RNaseH PF17917.1 GBG76285.1 - 4.8e-30 103.9 0.0 1.1e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76285.1 - 1.4e-23 82.8 0.0 4e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG76285.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Astro_capsid_p2 PF16580.5 GBG76286.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal tail of astrovirus capsid projection or spike RT_RNaseH_2 PF17919.1 GBG76287.1 - 1.2e-30 105.5 0.0 8.6e-16 57.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76287.1 - 2e-30 106.0 0.0 3.5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76287.1 - 5.4e-29 100.6 0.0 1.1e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76287.1 - 4e-16 58.9 0.0 8.3e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG76287.1 - 2e-05 24.7 0.0 4.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF4360 PF14273.6 GBG76288.1 - 3e-35 121.7 0.3 3.6e-35 121.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NPCBM_assoc PF10633.9 GBG76288.1 - 0.054 13.8 0.9 0.53 10.6 0.0 2.6 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase WHEP-TRS PF00458.20 GBG76289.1 - 0.051 13.7 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 WHEP-TRS domain Nop14 PF04147.12 GBG76289.1 - 0.094 10.9 15.8 0.13 10.4 15.8 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG76289.1 - 0.31 10.4 14.7 0.51 9.7 14.7 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GBG76289.1 - 0.41 8.7 18.3 0.62 8.1 18.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG76289.1 - 1.2 7.4 11.5 1.8 6.8 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Csm1_N PF18504.1 GBG76292.1 - 0.0051 17.1 0.3 0.023 15.0 0.3 2.1 1 0 0 1 1 1 1 Csm1 N-terminal domain MMM1 PF10296.9 GBG76292.1 - 0.2 10.7 1.7 0.32 10.0 1.7 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Fib_alpha PF08702.10 GBG76292.1 - 0.26 11.5 2.6 0.49 10.6 0.9 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 GBG76292.1 - 1.8 8.8 9.3 0.12 12.6 0.7 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4360 PF14273.6 GBG76294.1 - 4.1e-46 157.1 0.0 4.6e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Gal-bind_lectin PF00337.22 GBG76295.1 - 5.9e-34 116.5 0.0 1.2e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Galactoside-binding lectin Galactosyl_T PF01762.21 GBG76295.1 - 7.5e-30 104.2 0.1 2.9e-29 102.3 0.1 1.8 2 0 0 2 2 2 1 Galactosyltransferase SARAF PF06682.12 GBG76295.1 - 0.015 15.0 0.6 0.015 15.0 0.6 1.6 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Fringe PF02434.16 GBG76295.1 - 0.19 11.1 0.0 0.46 9.9 0.0 1.6 2 0 0 2 2 2 0 Fringe-like SR-25 PF10500.9 GBG76295.1 - 0.23 11.0 15.9 0.55 9.8 15.9 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Retrotrans_gag PF03732.17 GBG76296.1 - 0.0017 18.6 0.1 0.0017 18.6 0.1 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein DUF16 PF01519.16 GBG76296.1 - 3.4 8.2 5.5 8.5 6.9 2.2 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4366 PF14283.6 GBG76297.1 - 0.004 17.2 3.8 0.0051 16.9 3.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) NPR3 PF03666.13 GBG76297.1 - 0.021 13.6 3.0 0.023 13.5 3.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 GBG76297.1 - 0.025 13.8 2.0 0.025 13.8 2.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter THOC2_N PF16134.5 GBG76297.1 - 0.041 12.5 5.0 0.046 12.3 5.0 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Connexin PF00029.19 GBG76297.1 - 0.067 12.9 2.7 0.062 13.0 2.7 1.1 1 0 0 1 1 1 0 Connexin Orf78 PF06024.12 GBG76297.1 - 0.074 13.4 0.2 0.076 13.3 0.2 1.1 1 0 0 1 1 1 0 Orf78 (ac78) EIIBC-GUT_N PF03612.14 GBG76297.1 - 0.09 12.5 3.4 0.097 12.4 3.4 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peroxin-13_N PF04088.13 GBG76297.1 - 0.13 12.6 0.1 0.13 12.6 0.1 1.0 1 0 0 1 1 1 0 Peroxin 13, N-terminal region CobT PF06213.12 GBG76297.1 - 0.14 11.5 17.5 0.13 11.6 17.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 GBG76297.1 - 0.15 10.8 6.9 0.15 10.8 6.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 GBG76297.1 - 0.17 12.0 5.5 0.18 12.0 5.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 GBG76297.1 - 0.18 11.0 10.9 0.17 11.0 10.9 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4746 PF15928.5 GBG76297.1 - 0.19 11.1 15.3 0.2 11.1 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Usp PF00582.26 GBG76297.1 - 0.19 12.2 6.2 0.19 12.2 6.2 1.0 1 0 0 1 1 1 0 Universal stress protein family BSP_II PF05432.11 GBG76297.1 - 0.39 10.4 24.3 0.5 10.0 24.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4337 PF14235.6 GBG76297.1 - 0.42 10.7 4.8 0.42 10.7 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Eapp_C PF10238.9 GBG76297.1 - 0.45 10.6 4.4 0.44 10.6 4.4 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF5523 PF17661.1 GBG76297.1 - 0.48 10.1 15.1 0.5 10.0 15.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Presenilin PF01080.17 GBG76297.1 - 0.6 8.8 4.4 0.62 8.8 4.4 1.1 1 0 0 1 1 1 0 Presenilin Prothymosin PF03247.14 GBG76297.1 - 0.61 10.6 32.9 0.74 10.3 32.9 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF3391 PF11871.8 GBG76297.1 - 0.62 10.6 7.5 0.67 10.5 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Paf1 PF03985.13 GBG76297.1 - 0.7 8.8 20.4 0.7 8.8 20.4 1.0 1 0 0 1 1 1 0 Paf1 RPN2_C PF18004.1 GBG76297.1 - 0.85 9.5 12.9 0.91 9.4 12.9 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain V_ATPase_I PF01496.19 GBG76297.1 - 0.9 7.4 6.7 0.87 7.4 6.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 GBG76297.1 - 1.1 8.2 5.2 1.1 8.1 5.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 GBG76297.1 - 1.1 9.7 7.0 1.2 9.6 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 ORC_WH_C PF18137.1 GBG76297.1 - 1.2 9.2 9.9 1.4 9.0 9.9 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Med4 PF10018.9 GBG76297.1 - 1.3 8.7 12.8 1.5 8.5 12.8 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 RAB3GAP2_C PF14656.6 GBG76297.1 - 1.3 7.1 5.7 1.3 7.2 5.7 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus TFB6 PF17110.5 GBG76297.1 - 1.5 8.6 10.0 1.5 8.6 10.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Mpp10 PF04006.12 GBG76297.1 - 1.7 7.0 20.7 1.8 6.9 20.7 1.0 1 0 0 1 1 1 0 Mpp10 protein Chloroa_b-bind PF00504.21 GBG76297.1 - 1.8 9.1 6.8 2.1 8.9 6.8 1.3 1 1 0 1 1 1 0 Chlorophyll A-B binding protein DUF4820 PF16091.5 GBG76297.1 - 1.9 7.8 8.9 1.9 7.8 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 GBG76297.1 - 1.9 8.3 12.2 1.9 8.2 12.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DARPP-32 PF05395.12 GBG76297.1 - 2.1 8.6 15.5 2.3 8.5 15.5 1.0 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF2428 PF10350.9 GBG76297.1 - 2.1 7.5 4.9 2.2 7.5 4.9 1.0 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) TMEM119 PF15724.5 GBG76297.1 - 2.3 8.2 10.9 2.5 8.1 10.9 1.0 1 0 0 1 1 1 0 TMEM119 family NOA36 PF06524.12 GBG76297.1 - 2.5 7.4 19.7 2.9 7.1 19.7 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG76297.1 - 3 5.8 26.7 3.2 5.7 26.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 GBG76297.1 - 3 7.7 18.5 3.4 7.5 18.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 GBG76297.1 - 3.1 5.9 22.4 3.4 5.8 22.4 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG76297.1 - 3.3 7.1 23.1 3.6 6.9 23.1 1.0 1 0 0 1 1 1 0 SDA1 Trypan_PARP PF05887.11 GBG76297.1 - 3.4 7.6 17.5 3.8 7.5 17.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.13 GBG76297.1 - 4 7.3 17.4 4.4 7.2 17.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SspB PF04386.13 GBG76297.1 - 4.2 7.2 10.0 4.5 7.1 10.0 1.1 1 0 0 1 1 1 0 Stringent starvation protein B XAP5 PF04921.14 GBG76297.1 - 4.6 7.0 12.1 5.2 6.8 12.1 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator HSP90 PF00183.18 GBG76297.1 - 5.7 5.7 16.4 5.8 5.7 16.4 1.0 1 0 0 1 1 1 0 Hsp90 protein MAP17 PF15807.5 GBG76297.1 - 5.8 7.2 12.4 6.2 7.1 12.4 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CDC45 PF02724.14 GBG76297.1 - 6.1 5.0 16.2 6.4 4.9 16.2 1.0 1 0 0 1 1 1 0 CDC45-like protein D123 PF07065.14 GBG76297.1 - 6.9 5.7 6.9 7.3 5.7 6.9 1.0 1 0 0 1 1 1 0 D123 Pox_Ag35 PF03286.14 GBG76297.1 - 7.2 6.3 15.3 8.2 6.2 15.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein YqfQ PF14181.6 GBG76297.1 - 7.3 6.8 7.2 8.6 6.5 7.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein SURF2 PF05477.11 GBG76297.1 - 7.9 6.1 10.8 8.6 6.0 10.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RNA_polI_A34 PF08208.11 GBG76297.1 - 8.9 6.3 15.5 10 6.2 15.5 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Astro_capsid_p PF12226.8 GBG76297.1 - 9.2 5.3 16.3 9 5.3 16.3 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SAGA-Tad1 PF12767.7 GBG76298.1 - 2.3e-39 135.6 0.0 2.2e-20 73.4 0.0 3.2 3 0 0 3 3 3 2 Transcriptional regulator of RNA polII, SAGA, subunit SR-25 PF10500.9 GBG76298.1 - 0.00013 21.6 9.8 0.00013 21.6 9.8 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein TAF4 PF05236.14 GBG76298.1 - 0.92 9.2 0.0 0.92 9.2 0.0 4.6 5 0 0 5 5 5 0 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 GBG76299.1 - 1.2e-36 126.7 0.0 1.6e-19 70.6 0.0 2.9 3 0 0 3 3 3 2 Transcriptional regulator of RNA polII, SAGA, subunit DUF601 PF04642.12 GBG76299.1 - 0.1 12.1 2.4 0.3 10.5 2.4 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF601 TAF4 PF05236.14 GBG76299.1 - 0.24 11.1 0.0 0.24 11.1 0.0 3.9 5 0 0 5 5 5 0 Transcription initiation factor TFIID component TAF4 family Plavaka PF18759.1 GBG76300.1 - 1.3e-26 93.7 0.7 2.9e-26 92.5 0.7 1.5 1 0 0 1 1 1 1 Plavaka transposase TFIIA PF03153.13 GBG76300.1 - 0.16 11.9 11.9 0.3 11.1 11.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ThiF PF00899.21 GBG76301.1 - 2.8e-105 351.1 0.0 1.4e-72 244.0 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GBG76301.1 - 1e-80 271.3 0.0 1.7e-80 270.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 GBG76301.1 - 5.4e-25 87.4 0.1 1.2e-24 86.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 GBG76301.1 - 5.1e-23 81.6 0.0 1.1e-22 80.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 GBG76301.1 - 1.4e-22 79.6 0.0 5.6e-22 77.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Histone PF00125.24 GBG76302.1 - 3.9e-10 40.2 0.2 1.2e-09 38.6 0.2 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ThiF PF00899.21 GBG76303.1 - 1.6e-103 345.3 0.0 1.5e-72 243.9 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GBG76303.1 - 1.1e-80 271.2 0.0 1.6e-80 270.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 GBG76303.1 - 5.8e-25 87.3 0.1 1.2e-24 86.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 GBG76303.1 - 4.4e-23 81.8 0.0 1.1e-22 80.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 GBG76303.1 - 1.6e-22 79.5 0.0 5.7e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle DUF3619 PF12279.8 GBG76304.1 - 0.022 15.1 5.9 0.061 13.6 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) ERM PF00769.19 GBG76304.1 - 0.1 12.4 9.8 0.13 12.0 9.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3584 PF12128.8 GBG76304.1 - 0.2 9.1 8.0 0.25 8.8 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rrn6 PF10214.9 GBG76304.1 - 8.1 4.8 9.5 11 4.4 9.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RVP_2 PF08284.11 GBG76305.1 - 1e-08 35.0 0.0 2.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76305.1 - 1.2e-05 25.8 0.0 3.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG76305.1 - 2.9e-05 24.2 0.3 0.00023 21.4 0.1 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG76305.1 - 0.00025 21.5 0.0 0.00056 20.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG76305.1 - 0.091 12.3 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) SlyX PF04102.12 GBG76305.1 - 1.3 9.6 3.8 1.7 9.3 0.1 3.0 4 0 0 4 4 4 0 SlyX BAR_2 PF10455.9 GBG76306.1 - 0.0039 16.4 14.4 0.064 12.4 2.6 2.2 1 1 1 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking TPR_MLP1_2 PF07926.12 GBG76306.1 - 0.0058 16.7 39.5 0.1 12.7 19.5 2.7 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 GBG76306.1 - 0.012 16.1 31.7 0.016 15.7 16.9 2.1 1 1 1 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 GBG76306.1 - 0.012 15.8 7.9 0.012 15.8 7.9 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 GBG76306.1 - 0.014 14.3 33.7 0.098 11.5 15.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein THOC7 PF05615.13 GBG76306.1 - 0.016 15.4 33.4 2.1 8.7 28.1 3.4 1 1 1 2 2 2 0 Tho complex subunit 7 NUDE_C PF04880.13 GBG76306.1 - 0.024 15.1 3.3 0.024 15.1 3.3 3.2 1 1 2 3 3 3 0 NUDE protein, C-terminal conserved region betaPIX_CC PF16523.5 GBG76306.1 - 0.044 13.6 18.2 0.33 10.8 2.4 3.4 1 1 1 3 3 3 0 betaPIX coiled coil HIP1_clath_bdg PF16515.5 GBG76306.1 - 0.072 13.7 38.3 0.11 13.2 9.0 3.5 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MAD PF05557.13 GBG76306.1 - 0.092 11.1 29.8 0.12 10.7 29.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein PRKG1_interact PF15898.5 GBG76306.1 - 0.14 13.0 31.0 0.32 11.9 10.4 3.6 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain OmpH PF03938.14 GBG76306.1 - 0.16 12.3 37.9 0.12 12.8 8.8 3.1 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DPM3 PF08285.11 GBG76306.1 - 0.35 11.1 2.6 3.4 7.9 0.3 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Leu_zip PF15294.6 GBG76306.1 - 0.41 10.1 26.0 2 7.9 14.8 2.1 1 1 1 2 2 2 0 Leucine zipper GAS PF13851.6 GBG76306.1 - 0.73 9.2 35.4 1.2 8.4 6.5 3.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 GBG76306.1 - 0.83 9.1 34.1 2.6 7.5 21.1 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 ATG16 PF08614.11 GBG76306.1 - 1 9.5 39.5 0.36 11.0 17.5 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) IFT57 PF10498.9 GBG76306.1 - 1.5 7.8 23.3 3.9 6.3 6.0 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 HrpB7 PF09486.10 GBG76306.1 - 1.7 9.0 36.4 2.4 8.5 5.7 2.6 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) TFIIA PF03153.13 GBG76306.1 - 2.1 8.3 19.6 2.7 7.9 19.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DICT PF10069.9 GBG76306.1 - 2.5 7.9 10.5 0.54 10.0 0.2 2.2 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system APG6_N PF17675.1 GBG76306.1 - 2.6 8.6 37.6 1.3 9.6 8.3 3.1 1 1 1 2 2 1 0 Apg6 coiled-coil region YabA PF06156.13 GBG76306.1 - 2.7 8.7 26.4 4.1 8.1 6.2 3.7 1 1 3 4 4 4 0 Initiation control protein YabA Rootletin PF15035.6 GBG76306.1 - 3.6 7.6 31.0 7.4 6.5 7.3 3.6 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 GBG76306.1 - 4 7.5 31.2 0.19 11.8 18.1 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus SHE3 PF17078.5 GBG76306.1 - 4.2 7.0 18.2 7.6 6.2 18.2 1.4 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 ADIP PF11559.8 GBG76306.1 - 4.5 7.3 34.5 13 5.8 7.3 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TBK1_CCD1 PF18394.1 GBG76306.1 - 5.4 6.5 18.0 3.4 7.2 5.3 2.5 1 1 1 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 DUF4407 PF14362.6 GBG76306.1 - 5.5 6.2 26.8 66 2.7 26.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 GBG76306.1 - 6.3 6.6 18.0 13 5.6 4.2 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 FeoB_Cyto PF17910.1 GBG76306.1 - 7.9 7.1 9.8 6.2e+02 1.0 9.8 2.7 1 1 0 1 1 1 0 FeoB cytosolic helical domain Spc29 PF17082.5 GBG76306.1 - 9 6.1 14.4 78 3.0 13.8 2.1 1 1 0 1 1 1 0 Spindle Pole Component 29 TMF_DNA_bd PF12329.8 GBG76306.1 - 9.6 6.3 25.1 1.4 9.0 2.9 3.9 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding Cation_efflux PF01545.21 GBG76308.1 - 1e-40 139.6 0.7 1.6e-40 139.0 0.7 1.3 1 0 0 1 1 1 1 Cation efflux family RT_RNaseH PF17917.1 GBG76308.1 - 2.3e-19 69.6 0.0 4.5e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76308.1 - 5.6e-19 68.0 0.0 1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76308.1 - 1.9e-15 56.7 0.0 1.9e-15 56.7 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76308.1 - 6.2e-09 35.7 0.4 2.3e-08 33.8 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76308.1 - 1.7e-06 28.2 0.2 1.2e-05 25.4 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain Doppel PF11466.8 GBG76308.1 - 0.14 11.9 0.3 0.34 10.6 0.3 1.7 1 0 0 1 1 1 0 Prion-like protein Doppel RHD3 PF05879.12 GBG76309.1 - 0.017 13.3 1.1 0.016 13.4 1.1 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) FlxA PF14282.6 GBG76309.1 - 0.4 10.7 8.3 0.28 11.2 6.0 1.8 2 0 0 2 2 2 0 FlxA-like protein DivIC PF04977.15 GBG76309.1 - 1.4 8.7 7.9 2.1 8.2 7.5 1.5 1 1 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 GBG76309.1 - 3 8.5 7.1 44 4.8 4.6 2.4 1 1 1 2 2 2 0 SlyX RT_RNaseH_2 PF17919.1 GBG76310.1 - 1.3e-31 108.6 0.1 2.5e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76310.1 - 6e-28 97.9 0.0 9.8e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76310.1 - 3.1e-27 94.9 0.1 7.2e-27 93.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76310.1 - 8.2e-20 70.7 0.1 1.7e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76310.1 - 1.4e-12 47.8 0.0 5.2e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG76310.1 - 0.061 13.5 0.0 0.26 11.5 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger rve PF00665.26 GBG76311.1 - 4.3e-08 33.4 0.1 1.1e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain MMR_HSR1 PF01926.23 GBG76311.1 - 1.9e-05 24.7 0.0 0.00016 21.8 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GBG76311.1 - 0.00013 21.3 0.0 0.21 10.9 0.0 2.6 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 GBG76311.1 - 0.00053 19.9 0.0 0.0034 17.3 0.0 2.3 1 1 0 1 1 1 1 RsgA GTPase Chromo PF00385.24 GBG76311.1 - 0.0021 18.0 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 GBG76311.1 - 0.0028 18.2 5.9 0.027 15.0 0.2 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GBG76311.1 - 0.0037 17.0 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 GBG76311.1 - 0.0047 16.2 0.2 0.046 13.0 0.0 2.2 2 0 0 2 2 2 1 Septin TsaE PF02367.17 GBG76311.1 - 0.0073 16.3 0.0 0.2 11.6 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 GBG76311.1 - 0.0078 15.4 0.1 0.025 13.8 0.0 1.8 2 0 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 GBG76311.1 - 0.015 15.4 0.0 0.75 9.8 0.0 2.9 1 1 0 1 1 1 0 Dynamin family ABC_tran PF00005.27 GBG76311.1 - 0.022 15.3 0.2 0.32 11.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 GBG76311.1 - 0.023 15.0 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GBG76311.1 - 0.029 14.8 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain DUF815 PF05673.13 GBG76311.1 - 0.032 13.4 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GBG76311.1 - 0.047 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IIGP PF05049.13 GBG76311.1 - 0.06 12.4 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 GBG76311.1 - 0.064 13.0 0.1 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Vir_act_alpha_C PF10400.9 GBG76311.1 - 0.14 12.9 1.7 51 4.6 0.4 3.9 3 1 1 4 4 3 0 Virulence activator alpha C-term zf-RVT PF13966.6 GBG76311.1 - 0.38 11.5 2.6 1.1 10.0 2.6 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Fib_alpha PF08702.10 GBG76311.1 - 0.7 10.1 8.9 7.8 6.7 0.4 3.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF2497 PF10691.9 GBG76311.1 - 0.78 10.2 2.3 4.5 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) CBS PF00571.28 GBG76312.1 - 4e-25 88.0 0.1 4.8e-06 26.9 0.0 4.3 4 0 0 4 4 4 4 CBS domain AMPK1_CBM PF16561.5 GBG76312.1 - 2e-14 53.6 0.0 4.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Nop14 PF04147.12 GBG76314.1 - 0.00045 18.6 45.5 0.00054 18.3 45.5 1.1 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.15 GBG76314.1 - 0.00098 18.0 15.4 0.0011 17.8 15.4 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Drc1-Sld2 PF11719.8 GBG76314.1 - 0.16 11.5 24.1 0.23 11.0 24.1 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF4045 PF13254.6 GBG76314.1 - 1.1 8.8 18.3 1.3 8.5 18.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SDA1 PF05285.12 GBG76314.1 - 1.1 8.6 57.3 1.5 8.2 57.3 1.1 1 0 0 1 1 1 0 SDA1 Smg8_Smg9 PF10220.9 GBG76314.1 - 1.2 7.4 12.9 1.1 7.5 12.9 1.0 1 0 0 1 1 1 0 Smg8_Smg9 FAM60A PF15396.6 GBG76314.1 - 1.6 8.6 10.3 2.3 8.2 10.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 GBG76314.1 - 1.9 6.5 17.7 2.1 6.4 17.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCSAP PF15748.5 GBG76314.1 - 2.7 8.1 25.5 4 7.5 25.5 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated NPR3 PF03666.13 GBG76314.1 - 3.3 6.4 23.4 4.1 6.1 23.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF262 PF03235.14 GBG76314.1 - 4.1 7.5 10.9 4.4 7.4 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 SID-1_RNA_chan PF13965.6 GBG76314.1 - 4.6 5.5 5.9 4.5 5.6 5.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GPCR_chapero_1 PF11904.8 GBG76314.1 - 8 5.8 13.8 8.4 5.7 13.8 1.1 1 0 0 1 1 1 0 GPCR-chaperone Neur_chan_memb PF02932.16 GBG76314.1 - 8.6 6.3 8.4 9.2 6.2 8.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Plavaka PF18759.1 GBG76315.1 - 2.1e-20 73.2 0.6 3.7e-20 72.4 0.6 1.3 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 GBG76315.1 - 0.14 11.5 9.0 0.26 10.7 9.0 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG76315.1 - 0.26 9.5 9.3 0.48 8.6 9.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG76315.1 - 9.8 4.2 13.8 16 3.5 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family Thioredoxin PF00085.20 GBG76316.1 - 2.6e-48 162.2 1.0 1.3e-29 102.2 0.0 3.6 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 GBG76316.1 - 3.5e-25 89.0 1.5 4.5e-19 69.1 0.2 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 GBG76316.1 - 3e-10 39.9 0.4 3.5e-05 23.3 0.0 3.5 3 1 0 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GBG76316.1 - 7.3e-10 39.3 0.9 2.8e-06 27.7 0.1 3.6 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GBG76316.1 - 4.5e-06 26.7 0.1 0.011 15.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 GBG76316.1 - 9.3e-06 25.9 0.0 1.1 9.7 0.0 3.9 2 1 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 GBG76316.1 - 0.0023 17.8 0.1 3.7 7.3 0.0 3.7 3 1 0 3 3 3 1 F plasmid transfer operon protein HEAT_EZ PF13513.6 GBG76317.1 - 4.8e-27 94.0 23.2 9.2e-15 54.8 0.2 9.9 11 2 1 12 12 10 4 HEAT-like repeat HEAT PF02985.22 GBG76317.1 - 7.1e-20 69.4 18.2 0.0054 16.9 0.5 10.0 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 GBG76317.1 - 2.8e-15 56.5 3.8 0.00037 20.8 0.0 7.1 4 3 4 8 8 8 4 HEAT repeats IBN_N PF03810.19 GBG76317.1 - 2e-10 40.4 0.0 1.4e-09 37.7 0.0 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 GBG76317.1 - 2.3e-07 30.6 0.0 3.7 7.0 0.0 5.9 6 1 0 6 6 6 2 CLASP N terminal Cnd1 PF12717.7 GBG76317.1 - 5.1e-07 29.9 0.0 0.13 12.3 0.0 3.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GBG76317.1 - 1.4e-06 28.8 0.0 0.2 12.3 0.0 5.4 5 2 2 7 7 6 2 Vacuolar 14 Fab1-binding region UME PF08064.13 GBG76317.1 - 1.2e-05 25.1 0.1 1.4 8.9 0.0 4.5 4 1 0 4 4 4 2 UME (NUC010) domain Nipped-B_C PF12830.7 GBG76317.1 - 2e-05 24.6 0.1 0.001 19.0 0.0 2.8 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 GBG76317.1 - 0.00019 20.1 0.6 2 6.9 0.0 3.7 3 2 1 4 4 4 3 Adaptin N terminal region DUF3437 PF11919.8 GBG76317.1 - 0.00047 20.0 0.0 3 7.8 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) DNA_alkylation PF08713.11 GBG76317.1 - 0.0019 18.0 0.0 3.9 7.1 0.0 3.1 3 0 0 3 3 3 2 DNA alkylation repair enzyme Xpo1 PF08389.12 GBG76317.1 - 0.0032 17.5 0.1 4.4 7.4 0.0 3.7 3 1 0 3 3 3 1 Exportin 1-like protein MMS19_C PF12460.8 GBG76317.1 - 0.005 16.0 0.0 14 4.7 0.0 3.5 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal TAF6_C PF07571.13 GBG76317.1 - 0.056 13.8 0.0 0.93 9.9 0.0 3.1 4 1 0 4 4 3 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 GBG76317.1 - 0.11 12.6 14.5 1.7 8.8 0.0 6.4 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 GBG76317.1 - 0.14 11.8 1.5 11 5.7 0.1 3.3 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 GBG76318.1 - 4.8e-27 94.0 23.2 9.2e-15 54.8 0.2 9.9 11 2 1 12 12 10 4 HEAT-like repeat HEAT PF02985.22 GBG76318.1 - 6.9e-20 69.4 18.2 0.0054 16.9 0.5 10.0 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 GBG76318.1 - 2.8e-15 56.5 3.8 0.00037 20.8 0.0 7.1 4 3 4 8 8 8 4 HEAT repeats IBN_N PF03810.19 GBG76318.1 - 2e-10 40.4 0.0 1.4e-09 37.7 0.0 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 GBG76318.1 - 2.2e-07 30.7 0.0 3.7 7.0 0.0 5.9 6 1 0 6 6 6 2 CLASP N terminal Cnd1 PF12717.7 GBG76318.1 - 5.1e-07 29.9 0.0 0.13 12.3 0.0 3.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GBG76318.1 - 1.5e-06 28.7 0.0 0.2 12.3 0.0 5.4 5 2 1 6 6 5 1 Vacuolar 14 Fab1-binding region UME PF08064.13 GBG76318.1 - 1.2e-05 25.1 0.1 1.4 8.9 0.0 4.5 4 1 0 4 4 4 2 UME (NUC010) domain Nipped-B_C PF12830.7 GBG76318.1 - 2e-05 24.6 0.1 0.001 19.0 0.0 2.8 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 GBG76318.1 - 0.00017 20.3 0.4 2 6.9 0.0 3.7 3 2 1 4 4 4 3 Adaptin N terminal region DUF3437 PF11919.8 GBG76318.1 - 0.00047 20.0 0.0 3 7.8 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) DNA_alkylation PF08713.11 GBG76318.1 - 0.0019 18.0 0.0 3.9 7.1 0.0 3.1 3 0 0 3 3 3 2 DNA alkylation repair enzyme Xpo1 PF08389.12 GBG76318.1 - 0.0032 17.5 0.1 4.4 7.4 0.0 3.7 3 1 0 3 3 3 1 Exportin 1-like protein MMS19_C PF12460.8 GBG76318.1 - 0.005 16.0 0.0 14 4.7 0.0 3.5 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal TAF6_C PF07571.13 GBG76318.1 - 0.056 13.8 0.0 0.93 9.9 0.0 3.1 4 1 0 4 4 3 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 GBG76318.1 - 0.11 12.6 14.5 1.7 8.8 0.0 6.4 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 GBG76318.1 - 0.14 11.9 1.5 11 5.7 0.1 3.3 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis FA_hydroxylase PF04116.13 GBG76319.1 - 0.044 14.1 3.4 0.18 12.2 0.5 2.1 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily GCP_C_terminal PF04130.13 GBG76320.1 - 1.2e-61 208.9 0.4 2.1e-61 208.1 0.4 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GBG76320.1 - 4.5e-27 95.5 0.0 3e-21 76.4 0.0 2.6 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal GST_N_3 PF13417.6 GBG76321.1 - 6.9e-16 58.4 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG76321.1 - 9.7e-15 54.6 0.0 2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GBG76321.1 - 3.6e-07 30.4 0.0 7.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GBG76321.1 - 1.8e-05 24.7 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GBG76321.1 - 0.0011 19.7 0.0 0.0019 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 GBG76321.1 - 0.0014 19.2 0.0 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GBG76321.1 - 0.0018 18.4 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Herpes_capsid PF06112.11 GBG76321.1 - 3.2 7.8 17.8 5.7 7.0 17.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ribosomal_60s PF00428.19 GBG76321.1 - 8 7.1 9.4 2.6 8.7 6.1 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_60s PF00428.19 GBG76324.1 - 0.024 15.2 9.8 0.049 14.2 9.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3138 PF11336.8 GBG76324.1 - 0.05 12.2 2.5 0.068 11.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3138 PF11336.8 GBG76325.1 - 0.083 11.5 1.1 0.1 11.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_60s PF00428.19 GBG76325.1 - 0.72 10.5 12.5 0.18 12.4 9.0 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein rve PF00665.26 GBG76326.1 - 2.4e-08 34.2 0.0 4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain CCDC84 PF14968.6 GBG76326.1 - 0.16 11.6 0.1 0.23 11.0 0.1 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 RT_RNaseH_2 PF17919.1 GBG76327.1 - 4.2e-24 84.5 0.1 7.6e-24 83.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76327.1 - 2.2e-11 44.0 0.0 4.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RIFIN PF02009.16 GBG76329.1 - 3.7 7.4 6.1 6 6.7 6.1 1.3 1 0 0 1 1 1 0 Rifin Dapper PF15268.6 GBG76329.1 - 3.9 6.2 9.8 5.2 5.8 9.8 1.1 1 0 0 1 1 1 0 Dapper zf-CW PF07496.15 GBG76330.1 - 1.1e-11 44.6 3.1 2.7e-11 43.3 3.1 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger TFIIA PF03153.13 GBG76330.1 - 0.0034 17.4 5.9 0.0034 17.4 5.9 6.0 4 2 2 6 6 6 1 Transcription factor IIA, alpha/beta subunit SHMT PF00464.19 GBG76331.1 - 7.6e-182 604.3 0.6 1.9e-152 507.5 0.2 2.0 2 0 0 2 2 2 2 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 GBG76331.1 - 0.0036 16.5 0.0 0.013 14.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GBG76331.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Menin PF05053.13 GBG76332.1 - 0.13 10.6 2.2 0.16 10.3 2.2 1.1 1 0 0 1 1 1 0 Menin Pkinase PF00069.25 GBG76333.1 - 7.3e-64 215.7 0.0 9.6e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76333.1 - 3.6e-26 92.0 0.0 4.7e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 GBG76333.1 - 0.00028 20.5 0.1 0.00042 20.0 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 GBG76333.1 - 0.00044 19.7 0.0 0.073 12.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 GBG76333.1 - 0.00058 19.9 0.1 0.042 13.8 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GBG76333.1 - 0.0056 16.1 0.1 0.0086 15.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_52 PF07922.11 GBG76333.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 52 MTH865 PF07747.11 GBG76334.1 - 0.022 14.6 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 MTH865-like family Sigma70_ner PF04546.13 GBG76335.1 - 0.1 12.4 0.5 0.13 12.1 0.5 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region RT_RNaseH_2 PF17919.1 GBG76336.1 - 2e-35 120.8 0.6 3.7e-35 120.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76336.1 - 2.6e-29 101.6 0.0 4.6e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76336.1 - 1.2e-13 51.0 0.1 2.5e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76336.1 - 3.1e-05 23.6 0.1 6.2e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) O-FucT PF10250.9 GBG76337.1 - 4.8e-67 227.0 0.0 1.2e-66 225.7 0.0 1.7 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Band_7 PF01145.25 GBG76337.1 - 2.4e-16 60.3 0.2 5.6e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family FAM178 PF14816.6 GBG76337.1 - 0.26 10.2 4.8 0.2 10.6 3.4 1.5 1 1 0 1 1 1 0 Family of unknown function, FAM178 Kelch_6 PF13964.6 GBG76337.1 - 0.77 10.1 2.1 3.5 8.1 0.0 3.1 4 0 0 4 4 4 0 Kelch motif STI1 PF17830.1 GBG76339.1 - 1.1e-09 38.0 0.0 1.1e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 STI1 domain Asp_protease_2 PF13650.6 GBG76340.1 - 1.6e-07 31.8 0.0 4e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76340.1 - 3.8e-06 27.4 0.0 1.8e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG76340.1 - 4.9e-06 26.4 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG76340.1 - 6e-05 23.2 0.2 0.00036 20.8 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG76340.1 - 0.00041 20.1 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF4407 PF14362.6 GBG76340.1 - 2.3 7.5 7.1 2.1 7.6 5.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DDE_Tnp_4 PF13359.6 GBG76343.1 - 7.8e-21 74.4 0.0 1.3e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76343.1 - 6.9e-08 32.3 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG76343.1 - 0.0087 15.7 0.1 3.2 7.3 0.1 2.3 2 0 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG76344.1 - 9.3e-10 38.8 1.9 9.3e-10 38.8 0.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 GBG76345.1 - 8.1e-38 130.3 0.0 2.2e-37 128.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76345.1 - 1.1e-37 129.8 0.0 2e-37 128.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG76345.1 - 0.057 13.3 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG76345.1 - 0.058 12.2 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4713 PF15831.5 GBG76345.1 - 1.3 9.5 4.4 3.9 8.0 4.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) Aminoglyc_resit PF10706.9 GBG76348.1 - 5.8e-06 26.1 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Aminoglycoside-2''-adenylyltransferase Pkinase_Tyr PF07714.17 GBG76350.1 - 2.8e-38 131.7 0.0 4.4e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76350.1 - 1.6e-36 126.0 0.0 2.5e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG76350.1 - 0.0018 17.1 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG76350.1 - 0.034 14.1 0.0 0.31 10.9 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF4448 PF14610.6 GBG76350.1 - 0.15 11.8 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) PRIMA1 PF16101.5 GBG76350.1 - 0.7 9.9 8.4 4.1 7.5 8.4 2.2 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase_Tyr PF07714.17 GBG76351.1 - 3.7e-38 131.3 0.0 6.1e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76351.1 - 7.2e-36 123.9 0.0 1.1e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG76351.1 - 0.0056 15.5 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Herpes_UL73 PF03554.13 GBG76351.1 - 0.034 14.1 0.3 0.076 13.0 0.3 1.5 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein DUF4448 PF14610.6 GBG76351.1 - 0.21 11.4 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) PRIMA1 PF16101.5 GBG76351.1 - 6.6 6.8 6.3 0.32 11.0 0.5 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RT_RNaseH_2 PF17919.1 GBG76352.1 - 2e-29 101.5 0.0 4.6e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76352.1 - 3.3e-29 101.3 0.0 7.1e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76352.1 - 1.2e-15 57.7 0.0 2.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76352.1 - 7.3e-06 25.8 0.0 1.8e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG76352.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG76352.1 - 0.0016 19.0 0.0 0.0035 17.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76352.1 - 0.0033 17.9 0.0 0.0071 16.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG76352.1 - 0.0072 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG76352.1 - 0.34 10.5 0.1 0.34 10.5 0.1 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG76353.1 - 4.6e-29 101.5 0.0 2.9e-28 98.9 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76353.1 - 2.5e-06 28.0 0.0 8.3e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76353.1 - 3.9e-06 27.3 0.0 1.5e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG76353.1 - 7.5e-06 25.7 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG76353.1 - 0.00029 20.7 0.0 0.0007 19.4 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG76353.1 - 0.0014 18.4 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG76353.1 - 0.0018 18.5 0.2 0.0074 16.5 0.2 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein Pkinase_Tyr PF07714.17 GBG76354.1 - 1.2e-39 136.2 0.0 2.5e-39 135.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76354.1 - 2.8e-39 135.1 0.0 4.8e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG76354.1 - 7.6e-05 21.7 2.0 0.00032 19.6 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GBG76354.1 - 0.0051 16.8 0.1 0.69 9.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family CD34_antigen PF06365.12 GBG76354.1 - 0.05 13.2 0.8 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF659 PF04937.15 GBG76355.1 - 1.3e-05 25.1 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pkinase_Tyr PF07714.17 GBG76357.1 - 2.7e-33 115.3 0.0 5e-33 114.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76357.1 - 6.2e-33 114.3 0.0 8.3e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG76357.1 - 0.0081 16.1 0.1 0.25 11.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family 5_nucleotid_C PF02872.18 GBG76360.1 - 0.024 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain RVT_1 PF00078.27 GBG76361.1 - 9.4e-08 31.8 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG76361.1 - 0.0026 17.3 0.1 0.0078 15.8 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 GBG76362.1 - 4.5e-05 23.3 1.4 0.00012 22.0 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG76362.1 - 0.037 13.9 3.1 0.07 13.0 1.2 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG76362.1 - 0.12 12.4 0.4 0.12 12.4 0.4 1.9 2 0 0 2 2 2 0 Zinc knuckle Cas_Csx8 PF09657.10 GBG76362.1 - 1.3 7.9 6.9 2.1 7.3 6.9 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) Pkinase PF00069.25 GBG76363.1 - 9.8e-37 126.7 0.0 1.4e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76363.1 - 3.7e-36 124.8 0.0 6.9e-36 123.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG76363.1 - 0.00032 19.6 0.0 0.00055 18.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Dimer_Tnp_hAT PF05699.14 GBG76363.1 - 0.0066 16.2 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Adeno_E3_CR2 PF02439.15 GBG76363.1 - 0.88 9.4 3.4 2.3 8.0 3.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DDE_Tnp_4 PF13359.6 GBG76364.1 - 1.2e-18 67.3 0.1 9.8e-18 64.3 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76364.1 - 0.0002 21.0 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein Pkinase PF00069.25 GBG76366.1 - 6.7e-39 133.8 0.0 9.8e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76366.1 - 1e-38 133.1 0.0 1.7e-38 132.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG76366.1 - 0.00012 22.1 0.2 0.0023 17.9 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family TMEM154 PF15102.6 GBG76366.1 - 0.0051 16.7 0.1 0.056 13.3 0.0 2.4 2 1 1 3 3 3 1 TMEM154 protein family Pkinase_fungal PF17667.1 GBG76366.1 - 0.045 12.5 1.1 0.05 12.4 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase DAP10 PF07213.11 GBG76366.1 - 0.075 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 DAP10 membrane protein Kdo PF06293.14 GBG76366.1 - 0.23 10.8 0.1 0.45 9.8 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chorion_2 PF03964.15 GBG76366.1 - 3.6 8.5 12.4 0.085 13.7 3.5 2.4 2 0 0 2 2 2 0 Chorion family 2 Myb_DNA-bind_4 PF13837.6 GBG76367.1 - 1.7e-11 44.3 3.0 3.7e-11 43.2 3.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG76367.1 - 0.081 13.1 0.2 0.49 10.6 0.3 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pkinase_Tyr PF07714.17 GBG76368.1 - 1.8e-39 135.6 0.0 3.2e-39 134.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76368.1 - 5.2e-38 130.9 0.0 7.4e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG76368.1 - 0.0017 18.3 0.1 0.14 12.0 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG76368.1 - 0.098 11.4 0.3 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 GBG76369.1 - 1e-42 146.3 0.0 1.5e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76369.1 - 1.6e-40 139.0 0.0 3.4e-40 138.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG76369.1 - 0.00096 19.1 0.0 0.0026 17.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG76369.1 - 0.022 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GHL13 PF14883.6 GBG76369.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 TMEM154 PF15102.6 GBG76369.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Pkinase PF00069.25 GBG76370.1 - 1.5e-36 126.2 0.0 2.2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76370.1 - 7.6e-36 123.7 0.0 1.6e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG76370.1 - 0.00032 19.6 3.8 0.00053 18.9 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase Chorion_2 PF03964.15 GBG76370.1 - 4 8.3 16.7 0.12 13.2 8.9 2.3 2 0 0 2 2 2 0 Chorion family 2 TMEM52 PF14979.6 GBG76370.1 - 6.3 6.7 6.3 3.8 7.4 3.7 1.9 2 0 0 2 2 2 0 Transmembrane 52 RT_RNaseH_2 PF17919.1 GBG76371.1 - 1.7e-30 105.0 0.0 2.5e-16 59.6 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76371.1 - 1.1e-28 99.5 0.0 2.9e-28 98.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76371.1 - 1.3e-15 57.2 2.3 2e-15 56.6 0.0 2.5 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG76371.1 - 5.9e-11 42.6 0.0 2e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG76371.1 - 6.2e-07 29.1 0.0 2.5e-06 27.2 0.0 1.9 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG76371.1 - 6.6e-06 26.2 0.0 1.9e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF496 PF04363.12 GBG76371.1 - 0.59 10.2 5.9 1.3 9.1 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF496) PPP4R2 PF09184.11 GBG76372.1 - 0.0042 16.7 10.1 0.0048 16.5 10.1 1.1 1 0 0 1 1 1 1 PPP4R2 NOA36 PF06524.12 GBG76372.1 - 5.6 6.2 16.7 10 5.3 16.7 1.4 1 0 0 1 1 1 0 NOA36 protein RT_RNaseH PF17917.1 GBG76373.1 - 2.3e-22 79.3 0.0 1.5e-21 76.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76373.1 - 2.6e-21 75.5 0.0 7.4e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76373.1 - 2.3e-12 47.1 0.0 1e-11 45.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG76373.1 - 4.3e-09 36.4 0.6 8.8e-09 35.4 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76373.1 - 4.5e-08 32.9 0.0 7.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG76375.1 - 2.2e-37 128.9 0.0 3e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76375.1 - 3.8e-37 128.0 0.0 6.9e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG76375.1 - 0.044 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PQQ_3 PF13570.6 GBG76375.1 - 0.053 14.0 0.1 0.78 10.3 0.0 3.0 2 0 0 2 2 2 0 PQQ-like domain APH PF01636.23 GBG76375.1 - 0.087 12.7 0.0 0.29 11.0 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Herpes_gE PF02480.16 GBG76375.1 - 0.17 10.6 0.1 0.27 9.9 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E rve PF00665.26 GBG76376.1 - 2.4e-07 30.9 0.0 6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG76376.1 - 6.4e-07 29.1 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG76376.1 - 0.11 13.0 0.1 0.38 11.3 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF3347 PF11827.8 GBG76376.1 - 0.29 11.3 1.1 0.66 10.1 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) TPR_MLP1_2 PF07926.12 GBG76376.1 - 1.2 9.2 10.4 0.22 11.6 5.9 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pkinase_Tyr PF07714.17 GBG76377.1 - 6.9e-33 114.0 0.0 2.8e-32 112.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76377.1 - 6e-31 107.8 0.0 9.1e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SGL PF08450.12 GBG76377.1 - 0.071 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Fumerase_C PF05683.12 GBG76378.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Fumarase C-terminus Pkinase PF00069.25 GBG76379.1 - 4.2e-19 68.9 0.0 6.6e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76379.1 - 1.2e-12 47.7 0.0 2.1e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Insulin_TMD PF17870.1 GBG76379.1 - 0.077 13.1 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Cytomega_UL20A PF05984.12 GBG76379.1 - 0.61 10.4 2.7 17 5.8 0.0 3.1 3 0 0 3 3 3 0 Cytomegalovirus UL20A protein Pkinase_Tyr PF07714.17 GBG76380.1 - 2.9e-29 102.2 0.0 5.5e-29 101.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76380.1 - 2.7e-25 89.2 0.0 4.2e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG76380.1 - 0.035 12.9 0.1 0.095 11.5 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase SR-25 PF10500.9 GBG76380.1 - 0.16 11.6 7.0 0.34 10.5 7.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EcsB PF05975.12 GBG76380.1 - 0.2 10.5 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Pkinase_Tyr PF07714.17 GBG76381.1 - 5.2e-64 216.0 0.0 7.4e-36 123.8 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 GBG76381.1 - 5.3e-60 203.0 0.0 4e-37 128.0 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain PQQ_3 PF13570.6 GBG76381.1 - 9.3e-08 32.3 3.7 1.1 9.9 0.0 5.7 6 0 0 6 6 3 3 PQQ-like domain SIT PF15330.6 GBG76381.1 - 1.3e-06 28.9 0.2 1.1 9.7 0.0 3.4 3 0 0 3 3 3 2 SHP2-interacting transmembrane adaptor protein, SIT rOmpB PF12334.8 GBG76381.1 - 1.9e-05 24.3 0.0 0.82 9.1 0.0 3.3 3 0 0 3 3 3 2 Rickettsia outer membrane protein B TMEM154 PF15102.6 GBG76381.1 - 2.7e-05 24.1 0.0 4.7 7.1 0.0 3.5 3 0 0 3 3 3 2 TMEM154 protein family Pkinase_fungal PF17667.1 GBG76381.1 - 0.0019 17.1 0.0 0.091 11.5 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase S1FA PF04689.13 GBG76381.1 - 0.002 18.2 1.7 6.8 6.9 0.0 3.3 3 0 0 3 3 3 2 DNA binding protein S1FA APH PF01636.23 GBG76381.1 - 0.0023 17.9 0.1 1 9.3 0.1 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family TMEM51 PF15345.6 GBG76381.1 - 0.03 14.2 0.0 1.9 8.2 0.0 3.2 4 0 0 4 4 4 0 Transmembrane protein 51 DUF1616 PF07760.11 GBG76381.1 - 0.11 11.8 4.1 8.4 5.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1616) DUF5305 PF17231.2 GBG76381.1 - 0.2 11.0 0.0 65 2.8 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5305) DUF4454 PF14628.6 GBG76381.1 - 0.21 11.4 0.0 5.5 6.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4454) YlbD_coat PF14071.6 GBG76381.1 - 0.24 11.7 0.0 47 4.3 0.0 3.1 3 0 0 3 3 3 0 Putative coat protein Herpes_gE PF02480.16 GBG76381.1 - 0.27 9.9 2.2 2.3 6.9 0.0 2.7 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E DUF3483 PF11982.8 GBG76381.1 - 0.37 10.4 2.3 72 2.9 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3483) Insulin_TMD PF17870.1 GBG76381.1 - 3.3 7.9 15.1 4.7 7.4 1.2 3.5 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment RT_RNaseH_2 PF17919.1 GBG76382.1 - 3.6e-22 78.3 0.1 6.5e-22 77.5 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76382.1 - 2.3e-11 43.6 0.1 3.7e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76382.1 - 1.9e-09 37.7 0.0 3.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 GBG76383.1 - 8.5e-38 130.2 0.0 9.6e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76383.1 - 1.8e-37 129.1 0.0 1.2e-36 126.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG76383.1 - 0.026 13.3 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GBG76383.1 - 0.055 13.4 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-bind_4 PF13837.6 GBG76385.1 - 5.7e-08 33.0 6.1 5.7e-08 33.0 6.1 2.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain CEP209_CC5 PF16574.5 GBG76385.1 - 0.0016 18.6 2.7 0.0016 18.6 2.7 4.2 4 1 0 5 5 5 1 Coiled-coil region of centrosome protein CE290 Spc24 PF08286.11 GBG76385.1 - 0.4 10.9 7.0 0.66 10.2 0.1 3.7 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DivIC PF04977.15 GBG76385.1 - 0.85 9.4 20.8 0.027 14.2 1.5 4.5 2 1 2 4 4 4 0 Septum formation initiator KASH_CCD PF14662.6 GBG76385.1 - 1.5 8.6 25.9 0.029 14.2 8.3 3.9 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH LPP PF04728.13 GBG76385.1 - 2.2 8.8 7.9 0.23 11.9 0.5 3.2 3 1 1 4 4 4 0 Lipoprotein leucine-zipper SOGA PF11365.8 GBG76385.1 - 2.3 9.4 17.0 0.59 11.3 3.2 4.3 2 1 1 3 3 3 0 Protein SOGA DDE_Tnp_4 PF13359.6 GBG76386.1 - 5.3e-25 87.9 0.0 8.9e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76386.1 - 3.6e-11 43.1 0.0 6.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG76386.1 - 0.069 12.8 0.0 9.4 5.8 0.0 2.6 2 1 0 2 2 2 0 Transposase DDE domain Beach PF02138.18 GBG76386.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Beige/BEACH domain Peptidase_C48 PF02902.19 GBG76388.1 - 5.4e-09 36.2 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain gpUL132 PF11359.8 GBG76388.1 - 0.069 12.7 0.7 0.15 11.6 0.7 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 Pkinase_Tyr PF07714.17 GBG76389.1 - 2.1e-38 132.1 0.0 9.7e-38 129.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76389.1 - 1.9e-37 129.1 0.0 2.7e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG76389.1 - 0.049 12.4 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PQQ_3 PF13570.6 GBG76389.1 - 0.051 14.1 0.1 0.72 10.4 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain TMEM154 PF15102.6 GBG76389.1 - 0.087 12.7 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family APH PF01636.23 GBG76389.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 GBG76390.1 - 2.3e-66 223.9 0.0 1.1e-34 120.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76390.1 - 1.1e-64 218.2 0.0 5.2e-35 121.0 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG76390.1 - 0.00061 18.7 0.0 0.14 10.9 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 GBG76390.1 - 0.011 15.6 0.0 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF659 PF04937.15 GBG76391.1 - 7.5e-22 77.8 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) UPF0561 PF10573.9 GBG76391.1 - 0.0043 17.2 2.1 2 8.5 0.6 2.6 2 0 0 2 2 2 2 Uncharacterised protein family UPF0561 TYA PF01021.19 GBG76391.1 - 0.007 16.7 0.5 0.6 10.5 0.0 3.1 2 0 0 2 2 2 1 TYA transposon protein DDE_Tnp_4 PF13359.6 GBG76392.1 - 6e-19 68.3 0.0 1.1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76392.1 - 1.9e-07 30.9 0.0 3.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DUF745 PF05335.13 GBG76392.1 - 4.4e-06 26.6 2.5 4.4e-06 26.6 2.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF745) UPF0242 PF06785.11 GBG76392.1 - 0.0054 16.9 5.6 0.0054 16.9 5.6 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 GBG76392.1 - 0.0071 15.3 3.5 0.013 14.4 3.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin PF00261.20 GBG76392.1 - 0.03 13.7 6.5 0.065 12.6 6.5 1.6 1 0 0 1 1 1 0 Tropomyosin YkyA PF10368.9 GBG76392.1 - 0.045 13.4 0.3 0.076 12.7 0.3 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein GAS PF13851.6 GBG76392.1 - 0.14 11.5 4.2 0.34 10.2 4.2 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 GBG76392.1 - 0.27 11.7 2.4 0.71 10.3 2.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PEARLI-4 PF05278.12 GBG76392.1 - 0.45 10.0 3.0 0.78 9.3 3.0 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) MAD PF05557.13 GBG76392.1 - 0.58 8.5 7.6 0.81 8.0 7.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein PEP-utilisers_N PF05524.13 GBG76392.1 - 0.6 10.3 2.6 1.3 9.2 2.6 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Uds1 PF15456.6 GBG76392.1 - 0.73 10.0 5.2 2 8.6 5.2 1.7 1 0 0 1 1 1 0 Up-regulated During Septation Cnn_1N PF07989.11 GBG76392.1 - 0.8 9.9 9.4 1.4 9.1 0.3 3.4 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Fez1 PF06818.15 GBG76392.1 - 1.2 9.5 11.5 2.5 8.5 11.5 1.4 1 1 0 1 1 1 0 Fez1 FliJ PF02050.16 GBG76392.1 - 1.5 9.1 6.8 3.1 8.0 6.8 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein Cep57_CLD_2 PF14197.6 GBG76392.1 - 2.5 8.3 13.3 1.5 9.0 2.2 3.7 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 SOGA PF11365.8 GBG76392.1 - 4.4 8.5 8.8 4.8 8.4 4.3 2.5 2 0 0 2 2 2 0 Protein SOGA ATG16 PF08614.11 GBG76392.1 - 8.8 6.5 10.0 1.3 9.2 5.5 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HemX PF04375.14 GBG76392.1 - 9.5 5.4 6.8 0.6 9.4 1.7 1.4 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase zf-CCHC PF00098.23 GBG76393.1 - 7.5e-07 28.9 1.1 1.8e-06 27.7 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle GIY-YIG PF01541.24 GBG76393.1 - 0.005 17.1 1.1 0.011 16.0 0.0 2.2 2 0 0 2 2 2 1 GIY-YIG catalytic domain CDC48_N PF02359.18 GBG76393.1 - 0.043 14.0 0.0 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Prok-RING_1 PF14446.6 GBG76393.1 - 0.15 12.0 0.6 0.4 10.6 0.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CCHC_5 PF14787.6 GBG76393.1 - 1.1 9.1 7.6 0.063 13.0 1.8 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_1 PF00078.27 GBG76394.1 - 1.5e-24 86.7 0.0 9.7e-17 61.2 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76394.1 - 7.9e-24 83.6 0.0 1.9e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76394.1 - 4.5e-21 75.1 0.0 1.2e-20 73.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76394.1 - 9.6e-16 57.6 0.5 9.6e-16 57.6 0.5 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG76394.1 - 3.9e-09 36.7 0.0 1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG76394.1 - 0.001 18.9 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG76394.1 - 0.0044 17.2 0.6 0.016 15.4 0.2 2.2 2 0 0 2 2 2 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG76396.1 - 0.011 15.8 1.9 0.027 14.6 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG76396.1 - 0.11 12.4 3.2 0.22 11.4 3.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4337 PF14235.6 GBG76396.1 - 0.52 10.4 3.3 1.2 9.3 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1682 PF07946.14 GBG76396.1 - 5.3 6.1 14.7 8.3 5.5 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RT_RNaseH_2 PF17919.1 GBG76398.1 - 4.2e-57 190.4 0.0 1.1e-28 99.1 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76398.1 - 9.4e-57 192.1 1.3 2.1e-30 105.9 0.2 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76398.1 - 6e-51 171.1 0.7 4.7e-24 84.7 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase HTH_micro PF17007.5 GBG76398.1 - 0.018 13.9 0.4 1.7 7.4 0.1 2.4 2 0 0 2 2 2 0 HTH-like Phage_GPO PF05929.11 GBG76398.1 - 0.94 9.0 15.2 0.5 9.9 0.0 3.5 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG76399.1 - 1.7e-30 106.2 0.1 3e-30 105.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76399.1 - 1.8e-22 79.6 0.0 3.8e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76399.1 - 4.5e-14 52.3 0.0 9.7e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76399.1 - 9.1e-14 51.3 0.0 2.5e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76399.1 - 3.5e-13 49.8 0.1 1.1e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG76399.1 - 3.4e-11 42.9 0.0 8.2e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG76399.1 - 0.065 13.5 0.1 0.79 10.0 0.0 2.5 2 0 0 2 2 2 0 H2C2 zinc finger RVT_3 PF13456.6 GBG76399.1 - 0.099 12.5 0.2 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like RT_RNaseH_2 PF17919.1 GBG76400.1 - 5.5e-26 90.5 0.0 1e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76400.1 - 9.1e-25 87.5 0.1 1.3e-24 87.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76400.1 - 1e-23 83.6 0.0 1.8e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG76402.1 - 4.8e-08 32.9 0.0 8.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG76402.1 - 2.5e-07 30.5 0.0 5.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76402.1 - 0.00022 21.8 0.0 0.00054 20.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG76402.1 - 0.0027 17.5 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG76402.1 - 0.0029 18.1 0.0 0.0066 17.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG76402.1 - 0.021 14.7 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain GRP PF07172.11 GBG76402.1 - 1.1 10.0 10.3 1.8 9.3 1.8 2.7 2 0 0 2 2 2 0 Glycine rich protein family Dimer_Tnp_hAT PF05699.14 GBG76403.1 - 0.0003 20.5 0.2 0.00081 19.1 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Integrase_H2C2 PF17921.1 GBG76404.1 - 6.2e-16 58.2 0.1 1.3e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76404.1 - 0.0039 17.4 0.0 0.017 15.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain LMBR1 PF04791.16 GBG76404.1 - 1.1 8.1 14.5 1.6 7.6 14.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein IclR PF01614.18 GBG76404.1 - 4.2 7.2 15.2 4.2 7.2 1.0 2.5 2 1 0 2 2 2 0 Bacterial transcriptional regulator EzrA PF06160.12 GBG76405.1 - 0.012 13.9 4.2 0.017 13.3 4.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA RRP36 PF06102.12 GBG76405.1 - 0.13 12.2 10.1 0.018 15.0 5.0 1.9 1 1 1 2 2 2 0 rRNA biogenesis protein RRP36 DUF1635 PF07795.11 GBG76405.1 - 0.26 11.1 3.7 0.37 10.6 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4407 PF14362.6 GBG76405.1 - 0.61 9.4 3.7 0.8 9.0 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 GBG76405.1 - 0.7 9.3 10.5 0.57 9.6 8.6 1.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 Dynein_C PF18199.1 GBG76408.1 - 1.1e-103 346.6 0.0 1.7e-103 346.1 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 GBG76408.1 - 9.7e-56 188.1 0.0 2e-55 187.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GBG76408.1 - 6.7e-43 145.6 0.0 1.3e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain RT_RNaseH_2 PF17919.1 GBG76409.1 - 8.3e-33 112.4 0.4 3.8e-32 110.3 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76409.1 - 2.2e-30 105.8 0.2 3.6e-30 105.1 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76409.1 - 1.4e-28 99.3 0.6 3.4e-28 98.0 0.2 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76409.1 - 5.1e-17 61.7 0.3 1.1e-16 60.7 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG76409.1 - 0.037 14.3 0.0 0.15 12.3 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Rrn6 PF10214.9 GBG76409.1 - 6.9 5.0 6.7 10 4.5 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RT_RNaseH_2 PF17919.1 GBG76412.1 - 6.5e-25 87.1 0.0 6.2e-24 83.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76412.1 - 4.6e-22 78.3 0.0 2e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76412.1 - 1.6e-19 70.3 0.0 2.5e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76412.1 - 2.3e-08 33.9 0.0 5.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG76412.1 - 3.8e-07 30.6 0.0 8.7e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76412.1 - 1.7e-06 28.6 0.0 1.2e-05 25.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG76412.1 - 0.00024 20.9 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG76413.1 - 7.7e-29 100.8 0.1 7.7e-29 100.8 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG76413.1 - 1.8e-11 43.8 0.0 3.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG76414.1 - 6.6e-45 153.3 0.2 6.9e-25 87.9 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76414.1 - 1.9e-30 104.9 0.0 4.6e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76414.1 - 2.4e-28 98.5 0.2 5.2e-28 97.4 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG76414.1 - 8.7e-06 26.2 0.0 2.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG76414.1 - 0.00092 19.4 0.0 0.0053 17.0 0.0 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG76414.1 - 0.0013 19.3 0.0 0.0034 18.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG76414.1 - 0.0044 17.1 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1758 PF05585.12 GBG76414.1 - 0.0045 16.8 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG76414.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG76414.1 - 0.19 11.5 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG76415.1 - 7.8e-18 64.4 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76415.1 - 2.5e-16 59.8 0.0 4.2e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76415.1 - 6.3e-09 35.7 0.2 1.7e-08 34.3 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG76418.1 - 8.9e-06 25.9 1.0 0.00011 22.4 0.1 2.8 2 1 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG76419.1 - 2.7e-27 95.8 0.1 3.8e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG76420.1 - 2.5e-30 105.6 4.0 3.5e-10 39.8 0.1 3.2 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76420.1 - 2.3e-09 37.2 0.0 5.5e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76420.1 - 0.012 15.8 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase TAF4 PF05236.14 GBG76420.1 - 0.11 12.3 6.2 0.59 9.8 5.4 2.0 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family SMAP PF15477.6 GBG76420.1 - 0.26 12.3 1.3 1.2 10.2 0.4 2.2 2 0 0 2 2 2 0 Small acidic protein family RVT_1 PF00078.27 GBG76421.1 - 2.3e-28 99.2 0.1 4.7e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCD48 PF15799.5 GBG76421.1 - 0.0073 14.7 2.0 0.012 13.9 2.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 HALZ PF02183.18 GBG76421.1 - 0.043 14.1 1.9 0.15 12.3 1.9 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2385 PF09539.10 GBG76421.1 - 0.073 13.6 0.7 0.62 10.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) bZIP_2 PF07716.15 GBG76421.1 - 0.17 12.0 10.3 0.11 12.5 3.1 3.0 2 0 0 2 2 2 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 GBG76421.1 - 1.1 9.6 7.0 0.83 9.9 1.4 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain PIG-L PF02585.17 GBG76421.1 - 1.8 9.2 4.0 8.3 7.1 0.4 3.2 4 0 0 4 4 4 0 GlcNAc-PI de-N-acetylase bZIP_1 PF00170.21 GBG76421.1 - 3.8 7.7 7.7 0.33 11.1 1.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor PilZ PF07238.14 GBG76422.1 - 0.14 12.5 0.2 0.38 11.1 0.0 1.8 2 0 0 2 2 2 0 PilZ domain RT_RNaseH_2 PF17919.1 GBG76423.1 - 1.6e-34 117.9 0.1 3.1e-34 117.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76423.1 - 4e-31 107.4 0.1 7.9e-31 106.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76423.1 - 6.1e-29 101.1 0.1 1e-28 100.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76423.1 - 1.4e-18 66.7 0.2 3.2e-18 65.6 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76423.1 - 5.3e-16 58.9 0.0 2e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG76423.1 - 0.017 15.3 0.1 0.097 12.9 0.0 2.3 2 0 0 2 2 2 0 H2C2 zinc finger NAAA-beta PF15508.6 GBG76423.1 - 0.079 13.3 0.1 9.8 6.6 0.0 3.1 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF659 PF04937.15 GBG76424.1 - 9.8e-29 100.2 0.7 5e-25 88.1 0.7 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) CENP-Q PF13094.6 GBG76424.1 - 0.021 15.1 1.1 0.021 15.1 1.1 2.6 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-BED PF02892.15 GBG76424.1 - 0.048 13.7 1.9 0.14 12.2 1.9 1.8 1 0 0 1 1 1 0 BED zinc finger DUF29 PF01724.16 GBG76424.1 - 0.079 13.2 2.7 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF29 zf-Sec23_Sec24 PF04810.15 GBG76424.1 - 0.14 12.2 0.8 0.33 11.0 0.8 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger API5 PF05918.11 GBG76424.1 - 0.86 8.3 5.3 0.064 12.1 0.5 1.4 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) DUF4407 PF14362.6 GBG76424.1 - 4.4 6.6 9.0 0.13 11.6 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 GBG76424.1 - 5.8 6.8 8.2 16 5.3 8.2 1.7 1 0 0 1 1 1 0 Septum formation initiator RT_RNaseH_2 PF17919.1 GBG76425.1 - 6.5e-32 109.5 0.1 1.4e-31 108.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76425.1 - 7.7e-20 71.1 0.0 1.8e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76425.1 - 1.1e-13 51.2 0.1 2.1e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG76425.1 - 0.0025 17.7 0.3 0.016 15.1 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG76425.1 - 0.011 15.4 0.5 0.054 13.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DUF5095 PF17016.5 GBG76425.1 - 0.053 13.2 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) DUF45 PF01863.17 GBG76425.1 - 3.2 7.7 6.3 1.2 9.1 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF45 Uds1 PF15456.6 GBG76426.1 - 0.97 9.6 7.3 0.43 10.7 4.3 2.0 2 0 0 2 2 2 0 Up-regulated During Septation K_channel_TID PF07941.11 GBG76426.1 - 2.1 8.9 7.7 5.4 7.6 7.7 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RVT_1 PF00078.27 GBG76428.1 - 3.9e-29 101.8 0.1 5.4e-29 101.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76428.1 - 2.6e-20 72.3 0.0 4.4e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76428.1 - 2.3e-09 37.5 0.0 3.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG76430.1 - 4e-08 33.0 4.4 7.7e-08 32.1 4.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG76430.1 - 0.03 14.1 0.5 0.071 13.0 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Atg14 PF10186.9 GBG76430.1 - 0.74 8.8 6.2 1.1 8.3 6.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 GBG76430.1 - 0.99 7.9 12.0 1.4 7.3 12.0 1.1 1 0 0 1 1 1 0 Macoilin family SAP PF02037.27 GBG76430.1 - 4.6 7.1 8.9 0.4 10.5 0.2 3.4 4 0 0 4 4 4 0 SAP domain RVT_1 PF00078.27 GBG76431.1 - 1.1e-06 28.3 0.0 0.063 12.8 0.0 3.8 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) Fungal_KA1 PF16797.5 GBG76431.1 - 0.0041 16.8 0.4 2 8.1 0.1 2.9 2 0 0 2 2 2 2 Fungal kinase associated-1 domain Lipid_DES PF08557.10 GBG76431.1 - 0.0063 16.0 0.0 0.53 9.8 0.0 3.2 3 0 0 3 3 3 1 Sphingolipid Delta4-desaturase (DES) DUF1414 PF07208.11 GBG76431.1 - 0.018 15.0 0.5 11 6.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1414) Usp PF00582.26 GBG76431.1 - 0.11 12.9 0.2 0.32 11.5 0.2 1.7 1 0 0 1 1 1 0 Universal stress protein family DUF3978 PF13123.6 GBG76431.1 - 0.15 11.8 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) DUF4554 PF15091.6 GBG76431.1 - 1.3 7.9 4.0 2.3 7.0 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) RVT_1 PF00078.27 GBG76432.1 - 4.3e-05 23.1 0.0 0.091 12.3 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG76433.1 - 8.2e-32 110.2 0.1 1.6e-31 109.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG76433.1 - 0.0012 18.4 0.3 0.14 11.7 0.1 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) JmjC PF02373.22 GBG76433.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Radial_spoke_3 PF06098.11 GBG76433.1 - 2.8 7.1 14.5 6.6 5.9 14.5 1.6 1 0 0 1 1 1 0 Radial spoke protein 3 Helitron_like_N PF14214.6 GBG76434.1 - 4.5e-22 79.2 0.0 8.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 GBG76434.1 - 0.00085 18.6 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase zf-CCHC PF00098.23 GBG76435.1 - 1.7e-07 31.0 0.4 4e-07 29.8 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG76435.1 - 3.9e-05 23.3 0.0 0.041 13.4 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG76435.1 - 0.037 13.9 0.8 0.092 12.6 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG76436.1 - 1.3e-29 103.4 0.1 1.7e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76436.1 - 4.4e-21 74.8 0.0 2.4e-20 72.4 0.0 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76436.1 - 2.2e-10 40.7 0.0 7.9e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase FAE1_CUT1_RppA PF08392.12 GBG76436.1 - 0.22 10.8 0.0 7.2 5.8 0.1 2.1 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein BUD22 PF09073.10 GBG76437.1 - 0.033 13.5 35.0 0.066 12.6 35.0 1.4 1 0 0 1 1 1 0 BUD22 AAA_11 PF13086.6 GBG76437.1 - 0.25 11.1 10.4 0.57 9.9 10.4 1.5 1 0 0 1 1 1 0 AAA domain SDA1 PF05285.12 GBG76437.1 - 1.4 8.2 46.9 3 7.2 46.9 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG76437.1 - 2.8 6.0 44.3 5 5.2 44.3 1.3 1 0 0 1 1 1 0 Nop14-like family SH3BP5 PF05276.14 GBG76438.1 - 0.0013 18.5 0.6 0.0014 18.5 0.6 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) SF-assemblin PF06705.11 GBG76438.1 - 0.0037 16.7 1.8 0.0053 16.1 1.8 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin Cas_Csy4 PF09618.10 GBG76438.1 - 0.042 14.0 0.9 0.045 13.9 0.9 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) KAP_NTPase PF07693.14 GBG76438.1 - 0.046 13.0 0.7 0.053 12.8 0.7 1.1 1 0 0 1 1 1 0 KAP family P-loop domain DUF3987 PF13148.6 GBG76438.1 - 0.053 12.5 1.3 0.056 12.4 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RT_RNaseH PF17917.1 GBG76439.1 - 2.9e-18 66.1 0.0 6.8e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76439.1 - 2.9e-16 59.3 0.0 7.7e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76439.1 - 5.4e-06 26.1 0.0 5.5e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mannitol_dh_C PF08125.13 GBG76439.1 - 0.083 12.4 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain Presenilin PF01080.17 GBG76439.1 - 0.25 10.1 1.7 0.44 9.3 1.7 1.3 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 GBG76439.1 - 4.1 7.3 14.1 0.53 10.2 8.4 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal gag-asp_proteas PF13975.6 GBG76440.1 - 0.018 15.6 0.1 0.061 13.9 0.1 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG76440.1 - 0.022 15.0 0.2 0.071 13.4 0.2 1.8 1 1 1 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 GBG76440.1 - 0.027 14.8 0.2 0.086 13.2 0.1 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76440.1 - 0.052 14.2 0.1 0.15 12.7 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG76442.1 - 2.7e-23 81.9 0.0 7.2e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76442.1 - 1.2e-18 67.3 0.0 3.1e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76442.1 - 8.8e-18 64.6 0.1 3e-07 30.2 0.0 4.3 4 0 0 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76442.1 - 1.9e-05 24.6 0.0 8.1e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG76442.1 - 6.7e-05 23.4 0.0 0.00019 21.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76442.1 - 0.026 15.2 0.0 0.066 13.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG76442.1 - 0.045 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG76442.1 - 0.09 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG76443.1 - 2.8e-33 114.9 0.9 4.8e-33 114.2 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG76443.1 - 0.00016 21.4 2.1 0.0002 21.1 0.5 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG76445.1 - 5.4e-18 65.3 0.2 8.1e-18 64.7 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76445.1 - 3e-07 31.0 0.0 6.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76445.1 - 9.8e-07 29.3 0.0 2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG76445.1 - 8.7e-06 25.5 0.0 2.1e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG76445.1 - 0.00012 21.9 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG76446.1 - 0.001 19.3 4.3 0.0048 17.1 0.1 3.3 2 1 0 2 2 2 1 Retrotransposon gag protein GIT_CC PF16559.5 GBG76446.1 - 0.094 12.6 0.1 0.094 12.6 0.1 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.6 GBG76446.1 - 4.9 7.2 12.8 4.3 7.4 0.0 3.6 3 0 0 3 3 3 0 FlxA-like protein DUF4407 PF14362.6 GBG76446.1 - 6.4 6.0 17.7 6.4 6.0 8.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Retrotrans_gag PF03732.17 GBG76447.1 - 0.0086 16.3 0.1 0.054 13.8 0.0 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein Latrophilin PF02354.16 GBG76447.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region PapC_C PF13953.6 GBG76448.1 - 0.00026 20.7 24.9 1.2 9.0 0.9 6.7 1 1 6 7 7 7 6 PapC C-terminal domain RVT_1 PF00078.27 GBG76449.1 - 1.1e-25 90.5 0.1 2.1e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76449.1 - 1.2e-22 79.8 0.0 2.8e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76449.1 - 1.9e-17 63.1 0.1 4.8e-17 61.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG76449.1 - 5.1e-15 55.7 0.0 1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76449.1 - 1.3e-08 35.0 0.0 3.8e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG76449.1 - 4.8e-06 26.4 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76449.1 - 0.00033 21.2 0.0 0.0009 19.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG76449.1 - 0.0088 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76449.1 - 0.0097 16.4 0.0 0.039 14.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease APG17 PF04108.12 GBG76449.1 - 0.03 13.4 0.0 0.062 12.4 0.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg17 zf-H2C2 PF09337.10 GBG76449.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Rho_N PF07498.12 GBG76450.1 - 0.0042 17.0 0.4 0.0089 15.9 0.4 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain RVT_1 PF00078.27 GBG76450.1 - 0.012 15.2 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG76452.1 - 1.2e-25 90.4 0.0 2.1e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG76452.1 - 0.035 14.1 0.0 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L34 DUF4859 PF16151.5 GBG76453.1 - 0.29 11.0 3.9 2.6 8.0 0.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4859) RVT_1 PF00078.27 GBG76454.1 - 2.1e-20 73.2 0.7 6.7e-12 45.4 0.2 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76454.1 - 2.5e-07 31.2 0.0 5.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76454.1 - 1.4e-06 28.7 0.0 3.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG76454.1 - 4.6e-06 26.4 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG76454.1 - 0.00021 21.1 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG76454.1 - 0.0028 17.9 1.2 0.014 15.6 0.1 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Connexin PF00029.19 GBG76454.1 - 0.11 12.2 5.7 0.23 11.2 5.7 1.4 1 0 0 1 1 1 0 Connexin Eapp_C PF10238.9 GBG76454.1 - 0.24 11.5 5.8 0.79 9.8 5.8 1.8 1 0 0 1 1 1 0 E2F-associated phosphoprotein NPV_P10 PF05531.12 GBG76454.1 - 0.38 11.2 1.6 1.8 9.1 0.2 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DDHD PF02862.17 GBG76454.1 - 0.72 10.0 6.3 0.06 13.5 0.8 2.0 2 0 0 2 2 2 0 DDHD domain Hid1 PF12722.7 GBG76454.1 - 1.2 7.2 5.1 2.3 6.3 5.1 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAF PF15715.5 GBG76454.1 - 1.4 9.5 10.3 3.5 8.2 10.3 1.6 1 0 0 1 1 1 0 PCNA-associated factor histone like domain DUF4820 PF16091.5 GBG76454.1 - 9.7 5.5 10.7 26 4.1 10.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SDA1 PF05285.12 GBG76454.1 - 9.8 5.5 35.0 0.026 13.9 25.2 1.6 2 0 0 2 2 1 0 SDA1 RT_RNaseH_2 PF17919.1 GBG76455.1 - 1e-32 112.1 0.0 2.8e-32 110.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76455.1 - 4.6e-29 100.8 0.0 1.2e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76455.1 - 1.8e-16 60.4 0.0 3.6e-10 39.7 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76455.1 - 1.2e-06 28.3 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG76455.1 - 0.03 14.4 0.3 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG76455.1 - 0.097 13.3 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG76455.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease NIF PF03031.18 GBG76455.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Snapin_Pallidin PF14712.6 GBG76455.1 - 0.19 12.2 0.0 0.19 12.2 0.0 3.1 3 0 0 3 3 3 0 Snapin/Pallidin RVT_1 PF00078.27 GBG76456.1 - 3.3e-36 124.9 0.0 6.5e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76456.1 - 3e-30 104.2 0.0 6.6e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76456.1 - 3.9e-29 101.0 0.1 7.8e-29 100.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76456.1 - 5.1e-15 55.3 0.5 1e-14 54.3 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76456.1 - 0.001 19.2 0.0 0.003 17.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain ETC_C1_NDUFA5 PF04716.14 GBG76456.1 - 0.075 12.8 0.1 0.48 10.3 0.0 2.4 2 0 0 2 2 2 0 ETC complex I subunit conserved region DUF4392 PF14336.6 GBG76456.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) RT_RNaseH_2 PF17919.1 GBG76457.1 - 2.3e-30 104.6 0.0 5.9e-30 103.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76457.1 - 3.3e-25 88.4 0.0 7.9e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76457.1 - 8.5e-19 67.4 0.1 2e-18 66.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76457.1 - 1.5e-16 60.7 0.2 5.5e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG76457.1 - 5.5e-12 45.7 0.3 1.2e-11 44.6 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG76457.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF5095 PF17016.5 GBG76457.1 - 0.025 14.3 1.1 0.39 10.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) DUF563 PF04577.14 GBG76458.1 - 9.7e-22 78.1 3.1 4.2e-21 76.1 1.3 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF563) Retrotrans_gag PF03732.17 GBG76459.1 - 0.00067 19.9 11.0 0.0084 16.4 0.2 3.6 4 0 0 4 4 4 2 Retrotransposon gag protein Pentapeptide_2 PF01469.18 GBG76462.1 - 0.036 14.0 3.8 0.068 13.1 3.8 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) DUF659 PF04937.15 GBG76465.1 - 1.7e-07 31.2 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG76466.1 - 0.73 10.0 4.2 1.7 8.9 4.2 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG76468.1 - 1.2e-25 90.3 0.0 2.2e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76468.1 - 4.3e-25 87.6 0.0 4.1e-11 42.8 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76468.1 - 9.3e-25 86.9 0.0 2.9e-24 85.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76468.1 - 1.6e-15 56.9 0.2 6.1e-15 55.1 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG76468.1 - 4.2e-07 29.8 0.0 7.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG76468.1 - 0.00071 19.8 0.0 1.9 8.7 0.0 3.8 2 1 1 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG76468.1 - 0.0043 17.2 0.1 0.011 16.0 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG76469.1 - 1.6e-06 27.9 3.0 2.7e-06 27.2 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG76469.1 - 0.0013 18.5 0.4 0.0021 17.8 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4142 PF13628.6 GBG76469.1 - 0.055 13.7 2.3 0.081 13.2 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) zf-CCHC_5 PF14787.6 GBG76469.1 - 0.064 13.0 0.7 0.11 12.2 0.7 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Herpes_UL25 PF01499.16 GBG76469.1 - 0.25 9.8 2.1 0.31 9.5 2.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family RNA_pol_L_2 PF13656.6 GBG76470.1 - 0.085 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain RVT_1 PF00078.27 GBG76471.1 - 0.00037 20.1 0.0 0.022 14.3 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Sigma70_ner PF04546.13 GBG76472.1 - 0.014 15.3 7.4 0.014 15.3 7.4 2.8 2 1 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.11 GBG76472.1 - 0.83 9.7 10.0 2.8 7.9 10.0 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 GBG76472.1 - 7.4 4.7 26.0 0.069 11.4 13.6 2.2 1 1 1 2 2 2 0 CDC45-like protein Sigma70_ner PF04546.13 GBG76473.1 - 0.014 15.3 7.4 0.014 15.3 7.4 2.8 2 1 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.11 GBG76473.1 - 0.83 9.7 10.0 2.8 7.9 10.0 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 GBG76473.1 - 7.6 4.7 26.1 0.058 11.7 13.4 2.2 1 1 1 2 2 2 0 CDC45-like protein CDC45 PF02724.14 GBG76474.1 - 0.72 8.1 21.1 3.7 5.7 20.2 2.1 1 1 1 2 2 2 0 CDC45-like protein NOA36 PF06524.12 GBG76474.1 - 1.3 8.2 25.6 2.7 7.3 25.6 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2722 PF10846.8 GBG76474.1 - 3.4 6.5 7.0 5.4 5.8 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RRN3 PF05327.11 GBG76474.1 - 5.8 5.3 13.1 0.31 9.6 7.2 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 XdhC_C PF13478.6 GBG76475.1 - 0.0051 17.3 1.6 1.2e+02 3.2 0.0 4.5 4 0 0 4 4 4 0 XdhC Rossmann domain DUF3916 PF13079.6 GBG76475.1 - 0.034 14.0 0.3 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3916) DUF1810 PF08837.11 GBG76475.1 - 0.064 13.0 0.3 36 4.2 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1810) RVT_1 PF00078.27 GBG76476.1 - 1.3e-29 103.3 0.1 2.5e-29 102.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG76476.1 - 4.4e-05 23.3 0.4 9.3e-05 22.3 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Apc13p PF05839.11 GBG76476.1 - 0.026 14.7 1.8 0.084 13.1 1.8 1.8 1 0 0 1 1 1 0 Apc13p protein DUF3863 PF12979.7 GBG76476.1 - 0.065 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Retrotrans_gag PF03732.17 GBG76476.1 - 0.15 12.3 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein FYDLN_acid PF09538.10 GBG76478.1 - 0.0098 16.6 4.7 0.01 16.5 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) BUD22 PF09073.10 GBG76478.1 - 1.3 8.3 10.4 1.2 8.4 10.4 1.0 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.13 GBG76478.1 - 2.3 7.2 9.4 2.3 7.2 9.4 1.0 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.14 GBG76478.1 - 3.3 7.5 11.8 3.9 7.2 11.8 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 GBG76478.1 - 3.3 6.7 12.8 3.5 6.6 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GBG76478.1 - 5.2 5.0 13.6 4.8 5.1 13.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 GBG76479.1 - 9.5 4.9 11.0 12 4.5 11.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF659 PF04937.15 GBG76480.1 - 1.4e-25 89.9 0.0 4.1e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG76480.1 - 7.5e-10 38.5 0.5 1.7e-09 37.3 0.5 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Tim54 PF11711.8 GBG76480.1 - 0.58 8.9 8.3 0.12 11.2 3.9 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.11 GBG76480.1 - 4.3 5.8 10.0 7.6 5.0 10.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.12 GBG76480.1 - 7.5 5.4 6.6 13 4.7 6.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Asp_protease_2 PF13650.6 GBG76481.1 - 1.7e-06 28.5 0.0 3.9e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76481.1 - 7.9e-05 23.1 0.0 0.00029 21.3 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG76481.1 - 0.026 14.6 3.3 0.051 13.7 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 GBG76481.1 - 0.027 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase_Tyr PF07714.17 GBG76482.1 - 1e-68 231.4 0.0 1.5e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EDR1 PF14381.6 GBG76482.1 - 2.1e-58 197.3 0.0 6.1e-58 195.8 0.0 1.8 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 Pkinase PF00069.25 GBG76482.1 - 4.2e-56 190.2 0.0 7.1e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RVT_1 PF00078.27 GBG76482.1 - 7.6e-28 97.5 0.0 1.2e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76482.1 - 1.6e-08 34.8 0.0 4.1e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG76482.1 - 2.2e-05 24.3 0.0 6.3e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76482.1 - 0.00048 20.7 0.0 0.0072 16.9 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease APH PF01636.23 GBG76482.1 - 0.0026 17.7 0.1 0.0026 17.7 0.1 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family gag-asp_proteas PF13975.6 GBG76482.1 - 0.031 14.8 0.0 0.077 13.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG76482.1 - 0.083 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease eIF-1a PF01176.19 GBG76482.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Haspin_kinase PF12330.8 GBG76482.1 - 0.13 11.2 0.1 0.28 10.1 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain CCDC85 PF10226.9 GBG76482.1 - 0.84 9.3 5.0 0.1 12.2 0.1 2.0 2 0 0 2 2 1 0 CCDC85 family Presenilin PF01080.17 GBG76483.1 - 1.9 7.2 10.4 2.9 6.6 10.4 1.3 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG76484.1 - 0.008 15.7 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76485.1 - 1.1e-14 54.6 0.0 2.3e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Methyltransf_21 PF05050.12 GBG76485.1 - 1.6e-05 25.0 0.0 4.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase FkbM domain RVP_2 PF08284.11 GBG76485.1 - 2.1e-05 24.3 0.0 7.9e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76485.1 - 0.00014 22.4 0.0 0.00033 21.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76485.1 - 0.0019 18.7 0.0 0.0052 17.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease GSHPx PF00255.19 GBG76485.1 - 0.13 11.8 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione peroxidase Asp_protease PF09668.10 GBG76485.1 - 0.18 11.6 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG76486.1 - 0.0013 19.0 1.8 0.0033 17.7 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG76487.1 - 3.9e-29 101.7 0.2 8.1e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76487.1 - 2.8e-24 85.4 0.0 5.9e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76487.1 - 1.6e-22 79.4 0.0 3.7e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76487.1 - 2.4e-19 69.2 0.2 4.6e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76487.1 - 2.5e-08 34.1 0.0 7.6e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG76487.1 - 0.0056 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger APG17 PF04108.12 GBG76487.1 - 0.054 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Tudor-knot PF11717.8 GBG76487.1 - 0.083 12.8 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain CHASE6_C PF17150.4 GBG76487.1 - 0.13 13.0 0.0 11 6.8 0.1 3.2 3 0 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain RVT_1 PF00078.27 GBG76488.1 - 2.3e-24 86.2 0.2 3.7e-24 85.5 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LegC3_N PF18654.1 GBG76488.1 - 0.2 10.8 6.1 0.33 10.1 6.1 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain BAH PF01426.18 GBG76489.1 - 6e-25 87.5 0.1 1.5e-24 86.2 0.0 1.6 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 GBG76489.1 - 1.2e-08 34.7 10.9 1.2e-08 34.7 10.9 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 GBG76489.1 - 0.76 9.4 8.3 0.093 12.3 3.9 1.8 2 0 0 2 2 2 0 PHD-finger RVT_1 PF00078.27 GBG76490.1 - 2.1e-12 47.0 0.1 3.2e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SET PF00856.28 GBG76491.1 - 2.7e-19 70.2 0.1 2.7e-19 70.2 0.1 4.4 3 1 0 3 3 3 1 SET domain zf-C2H2_3rep PF18868.1 GBG76491.1 - 6.7e-11 43.0 0.4 2.2e-09 38.0 0.0 3.6 4 0 0 4 4 4 2 Zinc finger C2H2-type, 3 repeats Pre-SET PF05033.16 GBG76491.1 - 9e-10 39.2 8.6 9e-10 39.2 8.6 2.8 2 1 0 2 2 2 1 Pre-SET motif AWS PF17907.1 GBG76491.1 - 0.00041 20.3 2.3 0.0013 18.7 2.3 1.9 1 0 0 1 1 1 1 AWS domain WRC PF08879.10 GBG76491.1 - 0.02 14.6 35.8 0.96 9.2 0.0 6.9 6 0 0 6 6 6 0 WRC Zn-ribbon_8 PF09723.10 GBG76491.1 - 0.021 14.9 0.4 3.6 7.8 0.0 3.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3Hc3H PF13891.6 GBG76491.1 - 0.059 13.7 23.8 14 6.1 0.0 6.6 6 0 0 6 6 6 0 Potential DNA-binding domain zf-C2H2_4 PF13894.6 GBG76491.1 - 1.1 10.3 11.1 1.4 10.0 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger SUIM_assoc PF16619.5 GBG76492.1 - 3.4 7.8 9.9 18 5.5 0.7 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CBM_48 PF02922.18 GBG76493.1 - 6.1e-15 55.3 0.0 1.6e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 GBG76493.1 - 1.4e-10 41.3 0.0 3.8e-09 36.6 0.0 2.5 2 1 1 3 3 3 1 Alpha amylase, catalytic domain CBM_48 PF02922.18 GBG76494.1 - 6.1e-15 55.3 0.0 1.6e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 GBG76494.1 - 1.4e-10 41.3 0.0 3.8e-09 36.6 0.0 2.5 2 1 1 3 3 3 1 Alpha amylase, catalytic domain Myb_DNA-bind_5 PF13873.6 GBG76495.1 - 2.2e-05 24.4 0.3 3.2e-05 23.9 0.3 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG76495.1 - 0.00061 20.1 1.7 0.00088 19.6 1.7 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG76495.1 - 0.021 15.0 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG76497.1 - 1.5e-30 105.9 0.1 2.3e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76497.1 - 1e-13 51.4 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG76497.1 - 6.2e-06 26.0 0.3 5.3e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Transposase DDE domain PRP38 PF03371.15 GBG76498.1 - 1.6e-52 177.9 0.1 2.5e-52 177.3 0.1 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 GBG76498.1 - 1.8e-07 31.6 19.2 1.8e-07 31.6 19.2 5.4 1 1 4 5 5 5 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term z-alpha PF02295.17 GBG76498.1 - 0.0024 17.9 0.1 2.8 8.0 0.0 2.4 2 0 0 2 2 2 2 Adenosine deaminase z-alpha domain PPR_2 PF13041.6 GBG76499.1 - 1e-70 233.8 1.0 7.5e-13 48.5 0.0 10.7 5 2 6 11 11 11 9 PPR repeat family PPR_3 PF13812.6 GBG76499.1 - 1.6e-48 162.6 0.0 2.5e-08 33.9 0.0 6.1 5 1 1 6 6 6 6 Pentatricopeptide repeat domain PPR PF01535.20 GBG76499.1 - 8.5e-48 157.3 19.9 1.6e-05 24.8 0.0 13.3 12 2 0 12 12 12 9 PPR repeat PPR_1 PF12854.7 GBG76499.1 - 3.2e-43 145.1 0.1 1.3e-05 24.8 0.0 11.4 11 0 0 11 11 11 9 PPR repeat PPR_long PF17177.4 GBG76499.1 - 1.5e-19 70.2 0.0 1.3e-07 31.2 0.0 4.4 2 2 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP CDC45 PF02724.14 GBG76499.1 - 0.0018 16.7 10.8 0.0018 16.7 10.8 2.4 3 0 0 3 3 3 1 CDC45-like protein RPM2 PF08579.11 GBG76499.1 - 0.0034 17.8 0.0 3.6 8.0 0.0 3.7 3 1 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 GBG76499.1 - 0.0066 17.2 0.1 2.5 9.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat 5_3_exonuc PF01367.20 GBG76499.1 - 0.13 12.9 0.1 0.32 11.6 0.1 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Nop14 PF04147.12 GBG76499.1 - 2 6.5 34.6 1.4 7.1 29.2 2.3 2 0 0 2 2 2 0 Nop14-like family BRD4_CDT PF17105.5 GBG76501.1 - 0.3 10.7 4.5 0.58 9.8 4.5 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 NMD3 PF04981.13 GBG76502.1 - 5.4e-82 274.9 2.4 7.2e-82 274.5 2.4 1.2 1 0 0 1 1 1 1 NMD3 family DUF1221 PF06760.11 GBG76502.1 - 0.058 12.9 0.2 0.097 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) DUF1289 PF06945.13 GBG76502.1 - 0.11 12.3 5.5 15 5.5 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) DZR PF12773.7 GBG76502.1 - 0.93 9.6 13.2 4.5 7.4 0.3 3.5 2 1 1 3 3 3 0 Double zinc ribbon HypA PF01155.19 GBG76502.1 - 1.2 9.2 7.8 0.11 12.5 1.1 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sec61_beta PF03911.16 GBG76503.1 - 5.7e-19 67.9 0.1 7.9e-19 67.4 0.1 1.2 1 0 0 1 1 1 1 Sec61beta family Sec61_beta PF03911.16 GBG76505.1 - 5.7e-19 67.9 0.1 7.9e-19 67.4 0.1 1.2 1 0 0 1 1 1 1 Sec61beta family PMI_typeI PF01238.21 GBG76506.1 - 1.9e-99 333.4 0.0 5.9e-53 180.4 0.0 2.1 2 0 0 2 2 2 2 Phosphomannose isomerase type I Cpn60_TCP1 PF00118.24 GBG76507.1 - 3.5e-151 504.2 18.2 4e-151 504.0 18.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COPIIcoated_ERV PF07970.12 GBG76509.1 - 5.4e-30 104.9 0.2 1.2e-29 103.7 0.3 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GBG76509.1 - 7.5e-25 87.1 0.2 7.5e-25 87.1 0.2 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 GBG76509.1 - 8.3e-21 73.9 0.0 1.7e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GBG76509.1 - 2.8e-05 23.6 0.0 6.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GBG76509.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Synapsin_C PF02750.14 GBG76509.1 - 0.12 11.8 0.2 0.76 9.3 0.1 2.0 1 1 0 2 2 2 0 Synapsin, ATP binding domain PITH PF06201.13 GBG76510.1 - 3.1e-39 134.6 0.0 3.7e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain DHHC PF01529.20 GBG76511.1 - 2.3e-29 102.2 15.0 2.3e-29 102.2 15.0 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Mpp10 PF04006.12 GBG76511.1 - 0.00013 20.6 6.8 0.00016 20.3 6.8 1.1 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 GBG76511.1 - 0.0014 18.0 9.3 0.0019 17.7 9.3 1.1 1 0 0 1 1 1 1 BUD22 RRN3 PF05327.11 GBG76511.1 - 0.004 15.8 1.5 0.005 15.4 1.5 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 GBG76511.1 - 0.021 14.3 18.7 0.029 13.8 18.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG76511.1 - 0.073 11.3 19.4 0.093 10.9 19.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF5308 PF17233.2 GBG76511.1 - 0.17 12.1 0.3 0.24 11.6 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Menin PF05053.13 GBG76511.1 - 0.29 9.4 1.6 0.42 8.9 1.6 1.1 1 0 0 1 1 1 0 Menin MMU163 PF17119.5 GBG76511.1 - 0.31 10.2 4.2 0.55 9.3 4.2 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis RNA_pol_Rpc4 PF05132.14 GBG76511.1 - 0.52 10.7 4.8 0.86 10.0 4.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 GBG76511.1 - 0.79 7.7 25.4 1.1 7.3 25.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Coilin_N PF15862.5 GBG76511.1 - 1 9.2 6.8 2.3 8.0 6.8 1.5 1 0 0 1 1 1 0 Coilin N-terminus PPP4R2 PF09184.11 GBG76511.1 - 1.5 8.4 16.5 2.3 7.8 16.5 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 GBG76511.1 - 2.6 6.3 15.5 3.6 5.8 15.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG76511.1 - 2.6 6.5 22.2 3.6 6.1 22.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF913 PF06025.12 GBG76511.1 - 2.8 6.8 3.7 3.9 6.4 3.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GBG76511.1 - 3.8 6.2 5.5 5.8 5.6 5.5 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GBG76511.1 - 6.4 6.5 13.0 9.7 5.9 13.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PRIMA1 PF16101.5 GBG76511.1 - 7.6 6.6 9.2 20 5.2 9.2 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ribosomal_L6e PF01159.19 GBG76511.1 - 8 7.0 5.8 14 6.3 5.8 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e TRAP_alpha PF03896.16 GBG76511.1 - 9.8 5.3 14.2 20 4.3 14.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Siah-Interact_N PF09032.11 GBG76512.1 - 7.2e-11 42.3 0.1 1.6e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Siah interacting protein, N terminal CS PF04969.16 GBG76512.1 - 9.6e-11 42.5 0.0 1.7e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 CS domain SGS PF05002.15 GBG76512.1 - 6e-05 23.1 0.2 0.00013 22.0 0.2 1.5 1 0 0 1 1 1 1 SGS domain RVT_1 PF00078.27 GBG76513.1 - 4.4e-27 95.1 0.1 6.2e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFB6 PF17110.5 GBG76514.1 - 1.8 8.3 13.4 2.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH V_ATPase_I PF01496.19 GBG76514.1 - 2.8 5.7 5.9 3.9 5.3 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PK PF00224.21 GBG76515.1 - 1.1e-116 389.5 4.3 1.5e-116 389.1 4.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG76515.1 - 6.3e-17 61.9 0.0 1.6e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GBG76515.1 - 0.0012 18.0 0.3 0.0029 16.8 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 GBG76515.1 - 0.066 12.2 0.1 0.066 12.2 0.1 1.9 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain SNF2_N PF00176.23 GBG76516.1 - 1.9e-60 204.5 0.0 3e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG76516.1 - 2.3e-17 63.3 0.0 4.4e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG76516.1 - 7.6e-07 29.3 0.0 5.7e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CCDC50_N PF15295.6 GBG76516.1 - 0.00014 22.0 3.2 0.00038 20.6 3.2 1.8 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus ERCC3_RAD25_C PF16203.5 GBG76516.1 - 0.012 14.8 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 GBG76516.1 - 0.021 14.0 0.0 0.79 8.8 0.0 2.3 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 KxDL PF10241.9 GBG76517.1 - 0.17 12.2 0.1 0.17 12.2 0.1 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein Cellulose_synt PF03552.14 GBG76518.1 - 0 1029.3 11.4 3.2e-237 789.6 0.1 2.0 2 0 0 2 2 2 2 Cellulose synthase zf-UDP PF14569.6 GBG76518.1 - 2.4e-15 56.4 4.3 2.4e-15 56.4 4.3 2.0 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 GBG76518.1 - 5.7e-11 42.0 11.0 1.8e-10 40.4 11.0 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Glyco_trans_2_3 PF13632.6 GBG76518.1 - 3.9e-07 30.2 2.7 0.0025 17.8 2.2 2.9 2 1 0 2 2 2 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG76518.1 - 1.5e-05 24.9 0.1 7.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF3413 PF11893.8 GBG76518.1 - 0.046 12.9 1.0 0.08 12.1 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Glyco_tranf_2_3 PF13641.6 GBG76518.1 - 0.051 13.5 0.0 2.9 7.7 0.0 3.0 3 0 0 3 3 3 0 Glycosyltransferase like family 2 Baculo_IE-1 PF05290.11 GBG76518.1 - 1.4 8.9 5.5 1.3 8.9 2.9 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) RT_RNaseH PF17917.1 GBG76519.1 - 9.3e-22 77.3 0.0 1.7e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76519.1 - 1.7e-20 72.9 0.0 3.2e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76519.1 - 4.1e-12 46.0 0.1 9.4e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76519.1 - 6.5e-07 29.6 0.0 1.9e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG76519.1 - 0.006 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Histone PF00125.24 GBG76520.1 - 9.1e-17 61.6 0.0 9.1e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Peptidase_M16 PF00675.20 GBG76521.1 - 1.1e-54 184.5 0.3 1.7e-54 183.9 0.3 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GBG76521.1 - 3.2e-36 125.0 0.0 1.4e-35 122.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 GBG76521.1 - 0.011 14.9 0.4 0.025 13.7 0.4 1.5 1 1 0 1 1 1 0 Peptidase M16C associated GHMP_kinases_N PF00288.26 GBG76522.1 - 1.2e-06 28.6 0.2 1.2e-06 28.6 0.2 3.4 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GBG76522.1 - 0.0018 18.6 0.0 0.0049 17.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Pyr_redox_2 PF07992.14 GBG76523.1 - 2e-22 79.8 0.0 3.7e-22 78.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG76523.1 - 7.9e-05 23.1 0.0 0.21 12.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG76523.1 - 0.0043 16.3 0.0 0.28 10.4 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GBG76523.1 - 0.01 15.0 0.2 0.85 8.7 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Cdc6_C PF09079.11 GBG76524.1 - 1.2e-15 57.2 0.1 3.8e-15 55.6 0.1 1.9 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 GBG76524.1 - 1.1e-14 54.9 0.0 2.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain MBD PF01429.19 GBG76524.1 - 3.5e-10 39.4 0.3 1.1e-09 37.9 0.1 1.9 2 0 0 2 2 2 1 Methyl-CpG binding domain AAA PF00004.29 GBG76524.1 - 1.5e-08 35.2 0.0 4.4e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG76524.1 - 5.1e-07 30.2 0.4 4.5e-06 27.1 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 GBG76524.1 - 8.4e-05 22.6 0.4 0.00051 20.1 0.0 2.3 2 0 0 2 2 2 1 AAA lid domain AAA_30 PF13604.6 GBG76524.1 - 0.00028 20.6 0.1 0.00058 19.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GBG76524.1 - 0.0004 20.4 0.0 0.00083 19.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TniB PF05621.11 GBG76524.1 - 0.00065 19.2 0.4 0.0028 17.1 0.4 2.0 1 1 0 1 1 1 1 Bacterial TniB protein AAA_19 PF13245.6 GBG76524.1 - 0.001 19.4 0.2 0.0021 18.4 0.2 1.5 1 0 0 1 1 1 1 AAA domain AT_hook PF02178.19 GBG76524.1 - 0.0021 17.7 17.9 0.12 12.4 4.7 2.8 2 0 0 2 2 2 2 AT hook motif PIF1 PF05970.14 GBG76524.1 - 0.017 14.3 0.0 0.04 13.1 0.0 1.5 2 0 0 2 2 2 0 PIF1-like helicase AAA_28 PF13521.6 GBG76524.1 - 0.028 14.7 0.1 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GBG76524.1 - 0.036 14.6 0.1 0.41 11.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GBG76524.1 - 0.066 12.9 0.2 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiB PF07689.12 GBG76524.1 - 0.084 12.6 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 KaiB domain AAA_7 PF12775.7 GBG76524.1 - 0.13 11.7 0.0 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 GBG76524.1 - 0.15 11.8 0.3 0.47 10.2 0.1 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Pectinesterase PF01095.19 GBG76525.1 - 6.8e-58 195.7 0.3 9.7e-58 195.2 0.3 1.1 1 0 0 1 1 1 1 Pectinesterase DUF3537 PF12056.8 GBG76527.1 - 0.27 10.0 1.9 3.7 6.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3537) Slu7 PF11708.8 GBG76527.1 - 1.8 8.3 49.2 3.3 7.4 24.4 2.2 1 1 1 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor RRP7 PF12923.7 GBG76527.1 - 1.8 8.7 65.1 0.13 12.4 17.5 3.2 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain PS_pyruv_trans PF04230.13 GBG76527.1 - 5.4 6.8 7.4 8.6 6.2 0.9 2.2 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase Pox_Ag35 PF03286.14 GBG76527.1 - 6.6 6.5 62.0 0.4 10.4 28.6 2.5 1 1 1 2 2 2 0 Pox virus Ag35 surface protein DUF3807 PF12720.7 GBG76527.1 - 7.2 6.8 55.6 0.74 10.1 14.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) zf-C2H2_10 PF16588.5 GBG76530.1 - 0.36 10.6 1.0 0.67 9.7 1.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Retrotrans_gag PF03732.17 GBG76532.1 - 0.00013 22.2 0.2 0.00013 22.2 0.2 4.3 4 1 0 4 4 4 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG76532.1 - 0.025 15.2 2.2 0.025 15.2 2.2 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RVT_1 PF00078.27 GBG76533.1 - 7.7e-31 107.3 0.0 1.3e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76533.1 - 2.5e-21 75.9 0.0 5.8e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76533.1 - 1e-16 60.7 0.0 1.9e-15 56.7 0.0 2.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76533.1 - 5.8e-05 23.3 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG76534.1 - 3e-23 82.1 0.0 7.2e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76534.1 - 4.6e-23 81.2 0.0 1e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76534.1 - 1.3e-11 44.8 0.0 3.3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG76534.1 - 5.4e-11 42.4 0.1 1.2e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG76534.1 - 0.026 14.7 0.6 0.059 13.6 0.6 1.6 1 0 0 1 1 1 0 H2C2 zinc finger PDCD2_C PF04194.13 GBG76536.1 - 3.3e-37 128.3 0.0 3.3e-37 128.3 0.0 4.9 3 1 0 3 3 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 GBG76536.1 - 0.00018 21.6 18.9 0.00018 21.6 18.9 3.3 3 1 0 3 3 3 1 MYND finger Mpp10 PF04006.12 GBG76536.1 - 0.00099 17.7 50.3 0.00099 17.7 50.3 2.8 3 0 0 3 3 2 1 Mpp10 protein DUF4604 PF15377.6 GBG76536.1 - 0.0012 19.3 40.6 0.0012 19.3 40.6 3.7 3 1 0 3 3 2 1 Domain of unknown function (DUF4604) Smg8_Smg9 PF10220.9 GBG76536.1 - 0.23 9.7 11.5 0.31 9.3 11.5 1.2 1 0 0 1 1 1 0 Smg8_Smg9 DUF908 PF06012.12 GBG76536.1 - 0.97 8.8 3.5 1.7 8.0 3.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF262 PF03235.14 GBG76536.1 - 2.4 8.3 13.5 4.1 7.5 13.5 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF262 SAPS PF04499.15 GBG76536.1 - 4.4 6.0 19.9 7.1 5.3 19.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 GBG76536.1 - 5 5.9 18.4 8 5.2 18.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SID-1_RNA_chan PF13965.6 GBG76536.1 - 5.1 5.4 9.9 7.1 4.9 9.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 GBG76536.1 - 8.8 5.2 28.4 15 4.4 28.4 1.4 1 0 0 1 1 1 0 Solute carrier family 12 CDT1_C PF16679.5 GBG76537.1 - 8.6e-08 32.5 0.6 1.9e-07 31.4 0.6 1.6 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain gag-asp_proteas PF13975.6 GBG76538.1 - 0.00075 20.0 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76538.1 - 0.0061 17.2 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease CDT1 PF08839.11 GBG76539.1 - 6.4e-05 23.3 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 GBG76539.1 - 0.0089 16.4 1.1 0.039 14.4 0.7 2.2 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain DDE_Tnp_4 PF13359.6 GBG76541.1 - 1.1e-07 31.6 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76541.1 - 0.03 13.9 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein DUF659 PF04937.15 GBG76542.1 - 7.8e-10 38.8 0.0 1.4e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG76542.1 - 1.6e-05 24.6 0.3 2.9e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.17 GBG76543.1 - 0.0015 18.8 0.0 0.015 15.5 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein RNA_pol_3_Rpc31 PF11705.8 GBG76543.1 - 5.1 7.3 16.8 27 4.9 16.8 2.1 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RR_TM4-6 PF06459.12 GBG76543.1 - 9.3 6.0 10.9 15 5.3 10.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NTF2 PF02136.20 GBG76544.1 - 9.1e-27 94.0 0.3 1.6e-26 93.2 0.3 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 GBG76544.1 - 1.3e-10 40.9 0.0 3.5e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG76544.1 - 0.00036 20.6 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Peptidase_C48 PF02902.19 GBG76545.1 - 6.7e-14 52.2 2.4 1.3e-13 51.3 1.0 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF21 PF01595.20 GBG76546.1 - 2.8e-41 141.1 5.6 4.2e-41 140.6 5.6 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 GBG76546.1 - 4.2e-19 68.3 0.0 1e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 GBG76546.1 - 1.5e-13 51.0 1.6 4e-05 24.0 0.3 3.3 3 0 0 3 3 3 2 CBS domain TrbC PF04956.13 GBG76546.1 - 1.4 9.2 0.0 1.4 9.2 0.0 2.5 3 0 0 3 3 3 0 TrbC/VIRB2 family PfkB PF00294.24 GBG76548.1 - 1.1e-74 251.5 0.8 1.3e-74 251.2 0.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 GBG76548.1 - 0.00017 21.1 0.1 0.00053 19.4 0.0 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DDE_Tnp_4 PF13359.6 GBG76549.1 - 3.5e-23 82.0 0.0 3.1e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76549.1 - 4.2e-12 46.1 0.0 8.3e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG76549.1 - 1.7e-05 24.6 0.2 0.055 13.1 0.0 3.0 3 0 0 3 3 3 2 Transposase DDE domain gag-asp_proteas PF13975.6 GBG76551.1 - 3.8e-08 33.8 0.1 1e-07 32.4 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76551.1 - 2.2e-06 28.2 0.1 6.8e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG76551.1 - 0.0011 18.8 0.1 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease EF-hand_4 PF12763.7 GBG76552.1 - 2.6e-16 59.4 0.0 2.6e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 GBG76552.1 - 3.9e-09 35.4 0.0 0.0011 18.4 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GBG76552.1 - 4.7e-06 26.1 0.0 0.085 12.8 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 GBG76552.1 - 1.1e-05 25.8 0.0 0.0025 18.2 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 GBG76552.1 - 0.0025 17.2 0.0 0.034 13.7 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 GBG76552.1 - 0.0072 16.2 0.0 0.97 9.3 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair ALIX_LYPXL_bnd PF13949.6 GBG76552.1 - 0.012 14.9 4.2 0.019 14.3 4.2 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Exonuc_VII_L PF02601.15 GBG76552.1 - 5.3 6.5 7.2 8.2 5.9 7.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit gag-asp_proteas PF13975.6 GBG76553.1 - 0.0004 20.9 0.0 0.00096 19.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76553.1 - 0.0026 18.4 0.0 0.0055 17.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG76553.1 - 0.0078 16.0 1.0 0.012 15.4 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 GBG76553.1 - 0.009 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG76553.1 - 0.011 16.0 0.5 0.034 14.4 0.5 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG76553.1 - 0.061 13.1 0.9 0.16 11.8 0.0 2.1 3 0 0 3 3 3 0 Aspartyl protease zf-CCHC_6 PF15288.6 GBG76553.1 - 0.14 12.0 0.3 0.33 10.8 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG76553.1 - 0.23 11.6 1.5 0.42 10.8 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG76556.1 - 2.6e-66 223.3 2.2 7.1e-27 94.4 0.1 3.4 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76556.1 - 6.5e-56 186.5 0.0 9e-30 102.7 0.0 3.2 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76556.1 - 1.3e-44 150.7 0.1 2.4e-21 76.0 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76556.1 - 1.1e-17 63.9 1.3 2.2e-17 62.9 0.5 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG76556.1 - 1.7e-14 54.0 0.1 3.4e-11 43.4 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain Retrotrans_gag PF03732.17 GBG76556.1 - 9.9e-09 35.4 0.6 0.045 14.0 0.0 4.7 3 0 0 3 3 3 3 Retrotransposon gag protein DUF1564 PF07600.11 GBG76556.1 - 0.0029 17.3 0.0 2.1 8.0 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1564) rve_3 PF13683.6 GBG76556.1 - 0.08 12.7 0.2 17 5.3 0.0 2.9 2 0 0 2 2 2 0 Integrase core domain MutS_V PF00488.21 GBG76557.1 - 5e-13 49.5 0.0 1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V RVT_1 PF00078.27 GBG76557.1 - 1.7e-06 27.7 0.1 3.4e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76557.1 - 5.4e-05 23.8 0.0 0.00012 22.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76557.1 - 0.00042 20.1 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG76557.1 - 0.0014 19.1 0.0 0.0047 17.5 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease AAA_29 PF13555.6 GBG76557.1 - 0.0033 17.1 0.1 0.0081 15.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 GBG76557.1 - 0.0037 17.8 0.1 0.0098 16.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain Asp_protease PF09668.10 GBG76557.1 - 0.018 14.9 0.0 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease CPSase_L_D3 PF02787.19 GBG76557.1 - 0.027 14.8 0.1 0.083 13.2 0.1 1.8 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ABC_tran PF00005.27 GBG76557.1 - 0.094 13.2 0.2 0.45 11.0 0.1 2.2 2 0 0 2 2 2 0 ABC transporter Flu_NS2 PF00601.19 GBG76558.1 - 0.36 11.2 2.1 7 7.0 0.7 2.4 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) DUF659 PF04937.15 GBG76559.1 - 1.4e-31 109.4 0.2 2.7e-31 108.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG76559.1 - 7.7e-07 28.8 0.1 1.9e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NIF PF03031.18 GBG76559.1 - 0.024 14.4 0.6 0.85 9.4 0.1 2.4 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase PadR PF03551.14 GBG76559.1 - 0.16 12.0 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family RVT_1 PF00078.27 GBG76560.1 - 8.4e-55 185.7 0.4 7.7e-27 94.3 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MutS_V PF00488.21 GBG76560.1 - 6.4e-21 75.2 0.0 1.5e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain V RT_RNaseH PF17917.1 GBG76560.1 - 3.4e-20 72.3 0.9 9.9e-20 70.8 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76560.1 - 2.4e-18 66.0 0.1 3.3e-17 62.3 0.0 2.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG76560.1 - 7.6e-08 32.5 5.9 0.088 13.1 0.1 6.5 6 0 0 6 6 6 3 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG76560.1 - 0.0032 18.0 0.0 0.013 16.0 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76560.1 - 0.0074 16.9 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Matrilin_ccoil PF10393.9 GBG76560.1 - 0.087 12.7 2.2 16 5.5 0.0 3.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin RT_RNaseH_2 PF17919.1 GBG76561.1 - 4.2e-20 71.6 0.0 8.1e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76561.1 - 1.3e-16 60.8 0.0 2.9e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG76561.1 - 5.9e-09 36.1 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76561.1 - 6.2e-05 23.0 0.6 0.00012 22.2 0.6 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76561.1 - 0.00052 19.6 0.2 0.0062 16.1 0.2 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) FSA_C PF10479.9 GBG76562.1 - 0.025 12.8 0.4 0.034 12.3 0.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MSP1_C PF07462.11 GBG76562.1 - 0.32 9.6 4.4 0.13 11.0 1.1 1.8 1 1 1 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus zf-HC5HC2H_2 PF13832.6 GBG76563.1 - 4.8e-51 171.6 35.3 2.9e-26 91.8 8.9 4.9 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GBG76563.1 - 3.7e-43 145.7 32.2 4.1e-24 84.6 5.9 5.0 4 0 0 4 4 4 3 PHD-like zinc-binding domain PHD_2 PF13831.6 GBG76563.1 - 4e-19 67.9 10.5 3.2e-13 49.0 3.3 5.2 5 0 0 5 5 3 2 PHD-finger PHD PF00628.29 GBG76563.1 - 4.6e-17 61.6 52.2 7.2e-09 35.4 6.2 6.1 6 0 0 6 6 6 3 PHD-finger LacI PF00356.21 GBG76563.1 - 0.0053 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family FYVE_2 PF02318.16 GBG76563.1 - 0.011 15.9 0.1 0.011 15.9 0.1 4.7 5 0 0 5 5 4 0 FYVE-type zinc finger C1_1 PF00130.22 GBG76563.1 - 0.014 15.3 0.4 0.014 15.3 0.4 5.6 6 0 0 6 6 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HTH_31 PF13560.6 GBG76563.1 - 0.015 15.6 0.1 0.066 13.6 0.1 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HNF-1_N PF04814.13 GBG76563.1 - 0.047 14.3 0.0 0.047 14.3 0.0 3.0 3 0 0 3 3 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus CUT PF02376.15 GBG76563.1 - 0.073 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 CUT domain zf-UDP PF14569.6 GBG76563.1 - 0.23 11.6 12.1 0.82 9.8 3.6 3.4 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF2318 PF10080.9 GBG76563.1 - 0.9 9.7 8.9 11 6.2 1.7 3.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Ada3 PF10198.9 GBG76563.1 - 4.4 7.5 13.3 0.019 15.1 3.5 2.1 2 0 0 2 2 1 0 Histone acetyltransferases subunit 3 zf-RING_7 PF02591.15 GBG76563.1 - 6.6 7.0 12.8 3.1 8.1 0.2 4.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain DHR-2 PF06920.13 GBG76566.1 - 2.2e-131 439.1 0.0 3.1e-131 438.6 0.0 1.2 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 GBG76566.1 - 1.9e-30 106.1 0.0 4.1e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Mitofilin PF09731.9 GBG76566.1 - 0.34 9.7 25.5 0.66 8.7 25.5 1.5 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Protamine_P1 PF00260.20 GBG76566.1 - 4.3 7.5 35.7 9.2 6.5 13.6 2.7 2 0 0 2 2 2 0 Protamine P1 gag-asp_proteas PF13975.6 GBG76569.1 - 0.00025 21.6 0.1 0.0007 20.1 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76569.1 - 0.0017 19.0 0.0 0.0046 17.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Glyco_hydro_38N PF01074.22 GBG76570.1 - 9.7e-47 159.7 0.0 1.5e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain RVT_1 PF00078.27 GBG76570.1 - 9e-23 81.0 0.1 1.8e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Alpha-mann_mid PF09261.11 GBG76570.1 - 8.7e-21 73.9 0.0 2.5e-20 72.4 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 GBG76570.1 - 5.2e-20 72.4 0.1 2.6e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain RT_RNaseH_2 PF17919.1 GBG76571.1 - 2.3e-23 82.1 0.0 4.8e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76571.1 - 8.3e-23 80.7 0.1 2.9e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76571.1 - 4.9e-19 68.7 1.0 1.5e-12 47.8 0.0 3.6 3 0 0 3 3 3 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG76571.1 - 5.4e-15 55.2 0.3 2.7e-14 53.0 0.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76571.1 - 2.4e-08 33.8 0.2 5.4e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PaaX_C PF08223.11 GBG76571.1 - 0.042 14.1 0.1 0.24 11.7 0.0 2.5 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Retrotrans_gag PF03732.17 GBG76571.1 - 0.085 13.1 0.2 0.38 11.0 0.2 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein rve_3 PF13683.6 GBG76571.1 - 0.1 12.4 0.1 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 Integrase core domain zf-H2C2 PF09337.10 GBG76571.1 - 0.16 12.2 0.2 0.52 10.6 0.1 2.0 2 0 0 2 2 2 0 H2C2 zinc finger CDH1_2_SANT_HL1 PF18375.1 GBG76571.1 - 0.16 12.6 0.1 1.1 10.0 0.0 2.4 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 RT_RNaseH_2 PF17919.1 GBG76572.1 - 1.6e-23 82.6 0.0 3e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76572.1 - 7.9e-23 80.7 0.0 1.8e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76572.1 - 1.4e-19 70.5 0.8 8.9e-13 48.5 0.0 3.6 3 0 0 3 3 3 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG76572.1 - 2.7e-15 56.2 0.3 1.7e-14 53.6 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76572.1 - 3.6e-08 33.2 0.2 7.4e-08 32.2 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PaaX_C PF08223.11 GBG76572.1 - 0.023 15.0 0.2 0.15 12.4 0.0 2.5 3 0 0 3 3 3 0 PaaX-like protein C-terminal domain rve_3 PF13683.6 GBG76572.1 - 0.04 13.7 0.1 0.94 9.3 0.0 3.2 3 0 0 3 3 3 0 Integrase core domain DUF45 PF01863.17 GBG76572.1 - 0.068 13.2 0.3 0.31 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 zf-H2C2 PF09337.10 GBG76572.1 - 0.081 13.2 0.3 0.34 11.2 0.1 2.2 2 0 0 2 2 2 0 H2C2 zinc finger CDH1_2_SANT_HL1 PF18375.1 GBG76572.1 - 0.086 13.5 0.0 0.71 10.6 0.0 2.5 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Fis1_TPR_C PF14853.6 GBG76572.1 - 0.13 12.4 0.0 0.52 10.4 0.0 2.1 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Integrin_b_cyt PF08725.11 GBG76572.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Glyco_hydro_38N PF01074.22 GBG76573.1 - 1.7e-19 70.3 0.3 2.8e-19 69.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain RT_RNaseH_2 PF17919.1 GBG76575.1 - 4.9e-32 109.9 0.1 8.4e-32 109.2 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76575.1 - 1.2e-28 99.5 0.2 2.2e-28 98.6 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76575.1 - 1.4e-20 73.1 0.5 3.5e-20 71.8 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76575.1 - 1.8e-08 34.2 0.2 3.4e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76575.1 - 9.7e-07 29.0 0.0 2.5e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG76575.1 - 0.0014 18.8 0.0 0.0014 18.8 0.0 2.2 3 0 0 3 3 3 1 H2C2 zinc finger DUF1478 PF07349.11 GBG76576.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) MADF_DNA_bdg PF10545.9 GBG76577.1 - 0.33 11.3 2.8 0.54 10.6 0.7 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG76578.1 - 2.9e-31 108.3 0.0 1.4e-30 106.1 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76578.1 - 1.8e-12 47.3 0.0 2.9e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG76578.1 - 0.017 14.7 0.1 3.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG76579.1 - 8.6e-10 38.9 0.6 8.6e-10 38.9 0.6 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG76579.1 - 0.16 12.3 0.5 0.43 10.9 0.5 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SLY PF12485.8 GBG76580.1 - 1.8 9.3 8.1 3.7 8.2 8.1 1.5 1 1 0 1 1 1 0 Lymphocyte signaling adaptor protein DUF4407 PF14362.6 GBG76580.1 - 4.3 6.6 16.9 5.8 6.2 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RT_RNaseH_2 PF17919.1 GBG76581.1 - 1.7e-33 114.6 0.0 4e-33 113.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76581.1 - 7.8e-30 103.3 0.3 3.9e-29 101.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76581.1 - 1.3e-28 100.1 0.0 2.1e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76581.1 - 3.5e-16 59.1 0.3 9e-16 57.7 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76581.1 - 1.5e-10 41.3 0.1 6.7e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG76581.1 - 1.8e-08 34.3 0.0 3.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76581.1 - 0.00059 20.4 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76581.1 - 0.0044 17.6 0.0 0.02 15.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG76581.1 - 0.029 14.6 0.1 1.2 9.5 0.0 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein EzrA PF06160.12 GBG76581.1 - 0.23 9.6 6.0 0.45 8.6 6.0 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 GBG76581.1 - 0.5 9.9 1.9 1.4 8.5 1.9 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 GBG76581.1 - 3.4 7.2 6.2 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HAD_2 PF13419.6 GBG76582.1 - 1.3e-17 64.5 0.0 2.4e-17 63.6 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GBG76582.1 - 5.1e-17 62.9 0.1 8.5e-17 62.1 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG76582.1 - 3e-09 36.8 0.1 6.1e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GBG76582.1 - 0.01 16.2 0.1 0.025 15.0 0.1 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GBG76582.1 - 0.13 12.4 0.1 4.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CENP-T_C PF15511.6 GBG76583.1 - 1.2e-07 31.8 0.0 2.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GBG76583.1 - 0.00016 21.9 0.1 0.00045 20.5 0.0 1.7 2 0 0 2 2 2 1 CENP-S protein TAF PF02969.17 GBG76583.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 GBG76583.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 GBG76583.1 - 0.03 14.6 0.0 0.077 13.3 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GBG76583.1 - 0.046 14.1 0.0 0.046 14.1 0.0 3.0 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GBG76583.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RT_RNaseH_2 PF17919.1 GBG76584.1 - 1e-20 73.6 0.0 1.6e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76584.1 - 6.8e-11 42.4 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76584.1 - 7.9e-11 41.9 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG76584.1 - 0.024 13.8 0.0 0.046 12.8 0.0 1.4 1 1 1 2 2 2 0 Autophagy protein Apg17 ARTD15_N PF18084.1 GBG76585.1 - 0.0074 16.5 1.6 0.49 10.7 0.1 3.7 2 1 1 3 3 3 1 ARTD15 N-terminal domain Spc7 PF08317.11 GBG76585.1 - 0.4 9.5 69.3 0.024 13.5 24.5 4.5 2 2 2 4 4 4 0 Spc7 kinetochore protein RT_RNaseH_2 PF17919.1 GBG76586.1 - 6e-40 135.3 0.0 5.2e-24 84.2 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76586.1 - 3.7e-39 133.2 0.1 2.3e-20 72.8 0.8 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76586.1 - 1.5e-07 31.6 0.0 4.8e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG76586.1 - 2e-07 30.8 0.9 0.001 18.6 0.1 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76586.1 - 1.7e-06 28.6 0.0 4.5e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76586.1 - 9.3e-06 25.5 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG76586.1 - 2.4e-05 24.8 0.0 5.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG76586.1 - 0.025 14.5 0.0 0.067 13.1 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG76586.1 - 0.098 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease BLOC1_2 PF10046.9 GBG76586.1 - 0.21 11.9 8.3 0.23 11.8 3.7 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2959 PF11172.8 GBG76586.1 - 0.23 11.6 5.3 0.49 10.5 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) DivIC PF04977.15 GBG76586.1 - 2.2 8.1 7.8 1.5 8.6 4.5 2.5 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 GBG76586.1 - 3.2 8.1 5.3 7.6 6.8 3.0 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 RT_RNaseH_2 PF17919.1 GBG76587.1 - 6.3e-40 135.3 0.0 5.3e-24 84.2 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76587.1 - 3.9e-39 133.2 0.1 2.4e-20 72.8 0.8 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76587.1 - 1.5e-07 31.6 0.0 4.9e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG76587.1 - 2.1e-07 30.7 0.9 0.0011 18.6 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76587.1 - 1.7e-06 28.5 0.0 4.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76587.1 - 9.4e-06 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG76587.1 - 2.4e-05 24.8 0.0 5.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG76587.1 - 0.025 14.5 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG76587.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease BLOC1_2 PF10046.9 GBG76587.1 - 0.22 11.8 8.3 0.23 11.8 3.7 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2959 PF11172.8 GBG76587.1 - 0.24 11.5 5.3 0.5 10.5 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) DivIC PF04977.15 GBG76587.1 - 2.3 8.0 7.8 1.5 8.6 4.5 2.5 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 GBG76587.1 - 3.2 8.1 5.3 7.8 6.8 3.0 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CBP4 PF07960.11 GBG76587.1 - 6.1 6.7 6.0 16 5.4 6.0 1.7 1 0 0 1 1 1 0 CBP4 RT_RNaseH_2 PF17919.1 GBG76588.1 - 1.7e-29 101.8 0.0 5.8e-29 100.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76588.1 - 5.8e-29 100.5 0.5 1.8e-28 98.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76588.1 - 2.8e-19 68.9 0.5 6.5e-19 67.8 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76588.1 - 1.5e-18 67.1 0.2 2.1e-17 63.4 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG76588.1 - 6.2e-14 52.0 0.1 1.4e-13 50.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG76588.1 - 0.0002 21.5 0.4 0.00075 19.7 0.1 2.2 2 0 0 2 2 2 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG76588.1 - 0.048 13.3 1.3 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Casc1_N PF15927.5 GBG76588.1 - 0.16 11.7 9.9 0.44 10.2 9.9 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus bHLH-MYC_N PF14215.6 GBG76589.1 - 2.9e-07 30.9 0.3 2.9e-07 30.9 0.3 2.7 1 1 1 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal RVT_1 PF00078.27 GBG76590.1 - 8.9e-26 90.8 0.1 1.7e-25 89.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76590.1 - 7.7e-19 67.9 0.1 4e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76590.1 - 9.8e-19 67.2 0.1 2.5e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG76590.1 - 2.1e-11 43.7 0.1 7.4e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4939 PF16297.5 GBG76590.1 - 0.013 15.3 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Snapin_Pallidin PF14712.6 GBG76590.1 - 0.15 12.5 0.0 0.15 12.5 0.0 3.1 3 0 0 3 3 3 0 Snapin/Pallidin SAP PF02037.27 GBG76592.1 - 0.014 15.1 0.1 0.044 13.6 0.1 1.9 1 0 0 1 1 1 0 SAP domain Paramyxo_C PF01692.18 GBG76592.1 - 0.057 12.8 2.5 0.084 12.3 2.5 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C Na_trans_assoc PF06512.13 GBG76594.1 - 0.065 13.5 4.3 0.084 13.1 4.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.14 GBG76594.1 - 0.53 8.5 9.1 0.64 8.2 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG76595.1 - 0.037 13.5 32.8 0.045 13.2 32.8 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG76595.1 - 0.048 13.4 26.9 0.06 13.1 26.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Serinc PF03348.15 GBG76595.1 - 0.081 11.8 1.5 0.13 11.2 1.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nop14 PF04147.12 GBG76595.1 - 0.13 10.5 32.7 0.17 10.1 32.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG76595.1 - 0.33 9.2 24.9 0.43 8.8 24.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 GBG76595.1 - 0.56 9.5 31.1 0.97 8.8 31.1 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Na_trans_assoc PF06512.13 GBG76595.1 - 1.5 9.0 21.4 4.7 7.4 21.4 1.8 1 1 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 GBG76595.1 - 1.6 8.0 32.9 2.5 7.4 32.9 1.3 1 0 0 1 1 1 0 BUD22 Neur_chan_memb PF02932.16 GBG76595.1 - 2.8 8.0 5.5 3.8 7.5 5.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 GBG76595.1 - 2.8 6.6 11.5 3.3 6.4 11.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 GBG76595.1 - 5.6 6.1 9.3 8 5.6 9.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Lin-8 PF03353.15 GBG76595.1 - 5.9 6.4 22.1 8.5 5.8 22.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 GBG76595.1 - 10 4.8 18.2 13 4.4 18.2 1.2 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG76596.1 - 1.3e-26 92.5 0.0 2.1e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76596.1 - 1.1e-24 86.7 0.0 2.5e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76596.1 - 1e-10 41.5 0.1 1.5e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IQ PF00612.27 GBG76596.1 - 1.6 8.7 4.0 2.3 8.2 0.9 2.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif DNA_pol_phi PF04931.13 GBG76597.1 - 3.6 5.6 45.5 4.4 5.3 45.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi RT_RNaseH_2 PF17919.1 GBG76598.1 - 4.9e-25 87.5 0.0 8.9e-25 86.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76598.1 - 3.3e-24 85.2 0.0 5.6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76598.1 - 4.8e-08 32.8 0.1 7.2e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG76598.1 - 2.1 8.6 18.3 3.5 7.9 18.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 GBG76598.1 - 3.6 6.8 32.3 5.7 6.2 32.3 1.2 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 GBG76598.1 - 7.4 6.9 17.1 13 6.1 17.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 gag-asp_proteas PF13975.6 GBG76602.1 - 8.7e-05 23.0 0.9 0.00025 21.5 0.1 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76602.1 - 0.0009 19.8 0.8 0.0027 18.3 0.1 2.2 3 0 0 3 3 3 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG76602.1 - 0.012 15.2 0.3 0.023 14.3 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG76602.1 - 0.034 14.0 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease UAA PF08449.11 GBG76603.1 - 3.5e-43 147.9 8.8 6.3e-43 147.1 8.8 1.3 1 0 0 1 1 1 1 UAA transporter family zf-CCHC PF00098.23 GBG76603.1 - 0.013 15.6 2.4 0.037 14.1 2.4 1.9 1 0 0 1 1 1 0 Zinc knuckle EspB_PE PF18625.1 GBG76603.1 - 3.6 8.1 6.7 3.4 8.2 1.2 2.9 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain Integrase_H2C2 PF17921.1 GBG76604.1 - 1.2e-31 108.6 10.5 2.9e-15 56.1 2.7 3.2 3 0 0 3 3 3 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG76604.1 - 4.3e-30 104.9 0.1 7.2e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76604.1 - 5.3e-25 87.4 0.0 1.3e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76604.1 - 1.8e-22 79.6 0.0 6.4e-22 77.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76604.1 - 2.6e-16 59.9 0.0 1.6e-10 41.2 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG76604.1 - 1.6e-06 28.2 3.5 0.0067 16.6 0.1 2.7 2 0 0 2 2 2 2 H2C2 zinc finger Cytochrome_C7 PF14522.6 GBG76604.1 - 0.034 14.2 0.1 4.1 7.5 0.0 2.8 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Retrotrans_gag PF03732.17 GBG76604.1 - 0.049 13.9 1.4 0.24 11.7 0.3 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2497 PF10691.9 GBG76604.1 - 4.8 7.7 6.9 0.71 10.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2497) RT_RNaseH_2 PF17919.1 GBG76605.1 - 2.6e-24 85.2 0.0 6.5e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76605.1 - 8.3e-23 80.7 0.0 2.6e-22 79.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76605.1 - 6.4e-19 68.3 0.0 1.3e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UAA PF08449.11 GBG76605.1 - 0.0017 17.7 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 UAA transporter family Retrotrans_gag PF03732.17 GBG76605.1 - 0.0025 18.1 1.6 0.027 14.8 0.0 3.4 2 1 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG76606.1 - 1.2e-08 35.1 0.0 3.5e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain MORN PF02493.20 GBG76606.1 - 4.3e-07 29.5 1.5 0.054 13.4 0.0 3.7 3 0 0 3 3 3 2 MORN repeat Chromo PF00385.24 GBG76606.1 - 0.0067 16.3 1.8 0.034 14.1 0.0 2.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG76606.1 - 0.14 12.4 1.7 0.45 10.8 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Tho2 PF11262.8 GBG76606.1 - 5.1 6.2 6.6 19 4.4 6.6 1.9 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Nmad4 PF18756.1 GBG76607.1 - 0.13 12.6 1.5 17 5.8 0.1 2.7 2 1 1 3 3 3 0 Nucleotide modification associated domain 4 WD40 PF00400.32 GBG76608.1 - 1.8e-37 126.7 22.6 9.2e-08 32.6 0.6 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG76608.1 - 1.7e-18 66.7 10.4 6.1e-07 29.6 0.5 5.3 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG76608.1 - 1.1e-06 28.6 2.2 0.011 15.6 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GBG76608.1 - 0.0082 15.5 0.0 0.04 13.3 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain VID27 PF08553.10 GBG76608.1 - 0.07 12.2 0.0 2.3 7.2 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 GBG76608.1 - 0.099 11.2 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain LDB19 PF13002.7 GBG76608.1 - 0.93 9.2 2.7 0.42 10.3 0.3 1.6 2 0 0 2 2 2 0 Arrestin_N terminal like Totivirus_coat PF05518.11 GBG76608.1 - 0.99 7.4 11.7 1.7 6.6 11.7 1.3 1 0 0 1 1 1 0 Totivirus coat protein Collagen PF01391.18 GBG76609.1 - 0.0013 18.4 16.1 0.0013 18.4 16.1 1.6 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Med6 PF04934.14 GBG76610.1 - 7.7e-35 119.6 0.0 1e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Fibin PF15819.5 GBG76610.1 - 0.04 13.7 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Fin bud initiation factor homologue NAC PF01849.18 GBG76611.1 - 2.5e-22 78.6 0.0 4e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 NAC domain ATP1G1_PLM_MAT8 PF02038.16 GBG76611.1 - 0.47 9.9 1.2 0.81 9.2 1.2 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family MFS_1 PF07690.16 GBG76612.1 - 1.4e-34 119.6 15.3 1.4e-34 119.6 15.3 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GBG76612.1 - 1.9e-07 30.3 13.0 0.0048 15.8 0.2 3.0 2 1 1 3 3 3 3 MFS_1 like family MFS_4 PF06779.14 GBG76612.1 - 0.00057 19.3 5.8 0.0012 18.2 5.8 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 GBG76612.1 - 0.003 16.5 4.0 0.003 16.5 4.0 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 GBG76612.1 - 0.42 8.9 5.2 1.4 7.1 0.1 2.8 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 GBG76612.1 - 0.58 8.5 5.6 1.3 7.4 5.6 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector DUF2157 PF09925.9 GBG76612.1 - 3.3 7.5 9.0 6.4 6.6 1.0 2.7 2 2 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2353 PF09789.9 GBG76613.1 - 0.011 15.1 7.2 0.018 14.4 7.2 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) THOC7 PF05615.13 GBG76613.1 - 0.022 15.1 2.4 0.022 15.1 2.4 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 KfrA_N PF11740.8 GBG76613.1 - 0.024 15.3 2.7 0.024 15.3 2.7 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term STAT_alpha PF01017.20 GBG76613.1 - 0.029 14.2 4.7 0.51 10.2 0.0 2.2 1 1 1 2 2 2 0 STAT protein, all-alpha domain Rac1 PF09632.10 GBG76613.1 - 0.051 12.8 1.0 3 6.9 0.3 2.1 1 1 1 2 2 2 0 Rac1-binding domain PRKG1_interact PF15898.5 GBG76613.1 - 0.17 12.8 10.5 0.6 11.0 0.9 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Cep57_CLD_2 PF14197.6 GBG76613.1 - 0.46 10.6 15.4 0.3 11.2 11.5 2.7 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Peptidase_M32 PF02074.15 GBG76613.1 - 0.62 8.8 4.6 0.85 8.3 4.6 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Spc7 PF08317.11 GBG76613.1 - 0.8 8.5 9.7 0.98 8.2 9.2 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.9 GBG76613.1 - 1.3 9.4 5.6 13 6.1 1.9 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein DASH_Duo1 PF08651.10 GBG76613.1 - 2.3 8.0 7.1 16 5.4 0.4 3.2 3 0 0 3 3 3 0 DASH complex subunit Duo1 HR1 PF02185.16 GBG76613.1 - 2.5 8.3 10.9 0.97 9.6 7.7 2.0 2 0 0 2 2 2 0 Hr1 repeat TPR_MLP1_2 PF07926.12 GBG76613.1 - 2.8 8.0 16.1 0.2 11.7 9.0 2.5 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein TEX13 PF15186.6 GBG76613.1 - 4 7.1 11.6 0.63 9.7 6.3 1.9 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF4200 PF13863.6 GBG76613.1 - 4.1 7.8 15.3 0.17 12.3 8.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-CCHC PF00098.23 GBG76614.1 - 8.8e-08 31.9 1.6 1.6e-07 31.1 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG76614.1 - 0.0061 16.2 0.8 0.0061 16.2 0.8 1.6 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger DUF2229 PF09989.9 GBG76614.1 - 0.016 14.9 0.1 0.02 14.6 0.1 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) zf-CCHC_6 PF15288.6 GBG76614.1 - 0.017 14.9 1.0 0.033 14.0 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG76614.1 - 0.034 14.0 0.8 0.051 13.4 0.8 1.2 1 0 0 1 1 1 0 Zinc knuckle Prothymosin PF03247.14 GBG76615.1 - 0.031 14.7 14.1 0.049 14.1 14.1 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family PRTP PF01366.18 GBG76615.1 - 0.25 9.3 1.6 0.3 9.1 1.6 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RXLR PF16810.5 GBG76615.1 - 0.32 11.4 2.7 0.46 10.9 2.7 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity PcfJ PF14284.6 GBG76615.1 - 5.1 7.0 8.1 6.4 6.6 7.6 1.5 1 1 0 1 1 1 0 PcfJ-like protein EF-hand_1 PF00036.32 GBG76619.1 - 5.9e-42 138.1 13.0 5.2e-10 38.1 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GBG76619.1 - 7.9e-36 122.3 5.5 6.6e-19 68.1 1.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG76619.1 - 8.2e-31 103.3 9.4 2.8e-09 36.1 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GBG76619.1 - 3.9e-30 103.5 12.4 1e-14 54.1 0.5 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GBG76619.1 - 4e-26 89.3 9.7 4.1e-06 26.0 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GBG76619.1 - 3.1e-16 59.4 0.4 8.5e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GBG76619.1 - 4.9e-11 42.5 2.4 1.6e-05 24.8 0.3 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GBG76619.1 - 1.5e-08 35.0 1.1 0.0018 18.6 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 GBG76619.1 - 3.4e-06 27.9 0.1 0.00081 20.2 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 GBG76619.1 - 1.6e-05 24.8 0.4 0.06 13.4 0.0 3.0 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 GBG76619.1 - 2e-05 24.7 6.0 0.062 13.5 1.0 2.9 1 1 2 3 3 3 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 GBG76619.1 - 7e-05 22.8 1.9 0.00016 21.7 0.7 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 GBG76619.1 - 0.00044 20.2 0.5 0.48 10.3 0.0 3.2 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 GBG76619.1 - 0.0012 19.6 0.4 6.3 7.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) TerB PF05099.13 GBG76619.1 - 0.0012 18.8 0.3 0.8 9.6 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 GBG76619.1 - 0.0028 18.0 1.1 1.5 9.2 0.1 2.8 2 1 1 3 3 3 1 RNA polymerase Rpb4 DUF5580 PF17743.1 GBG76619.1 - 0.0039 15.8 0.0 0.004 15.8 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF4497 PF14924.6 GBG76619.1 - 0.0048 17.4 0.0 0.73 10.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 GBG76619.1 - 0.0098 16.1 0.1 0.31 11.3 0.0 2.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 GBG76619.1 - 0.013 15.3 1.4 0.31 10.9 0.4 2.2 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 GBG76619.1 - 0.015 15.6 0.2 5 7.5 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain DUF1811 PF08838.10 GBG76619.1 - 0.022 15.0 0.0 4.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) MotA_activ PF09114.10 GBG76619.1 - 0.024 14.8 0.1 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain YqeY PF09424.10 GBG76619.1 - 0.048 13.7 1.3 0.18 11.8 0.6 1.9 1 1 1 2 2 2 0 Yqey-like protein SurA_N_3 PF13624.6 GBG76619.1 - 0.071 12.9 0.9 0.29 10.9 0.3 1.9 1 1 1 2 2 2 0 SurA N-terminal domain rve PF00665.26 GBG76620.1 - 5.3e-15 55.7 0.0 9.9e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG76620.1 - 1e-13 51.1 0.0 3.7e-13 49.4 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG76620.1 - 0.0073 16.1 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG76620.1 - 0.02 15.4 0.0 0.065 13.8 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG76620.1 - 0.067 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76620.1 - 0.087 13.5 0.0 0.27 11.9 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG76620.1 - 0.095 12.5 0.8 0.67 9.8 0.0 2.5 3 0 0 3 3 3 0 Aspartyl protease zf-CCHC PF00098.23 GBG76621.1 - 7.4e-07 29.0 4.2 1.9e-06 27.7 4.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG76621.1 - 0.2 11.4 2.6 0.64 9.8 2.6 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG76621.1 - 0.44 10.4 7.4 0.046 13.5 2.0 2.2 2 0 0 2 2 2 0 Zinc knuckle DDHD PF02862.17 GBG76621.1 - 1.8 8.7 5.6 4.5 7.4 5.6 1.7 1 0 0 1 1 1 0 DDHD domain Peptidase_C48 PF02902.19 GBG76624.1 - 4e-11 43.2 0.6 1.2e-10 41.6 0.6 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PTN13_u3 PF16599.5 GBG76624.1 - 0.0021 18.2 8.1 0.0035 17.4 8.1 1.3 1 0 0 1 1 1 1 Unstructured linker region on PTN13 protein between PDZ DUF1896 PF08989.10 GBG76624.1 - 0.0064 16.6 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1896) Plavaka PF18759.1 GBG76627.1 - 1.8e-22 80.0 0.1 5.3e-22 78.5 0.1 1.7 1 0 0 1 1 1 1 Plavaka transposase GIY-YIG PF01541.24 GBG76627.1 - 4e-08 33.4 0.0 7.6e-07 29.3 0.0 2.8 2 0 0 2 2 2 1 GIY-YIG catalytic domain LCM PF04072.14 GBG76627.1 - 0.039 13.9 0.2 0.11 12.4 0.2 1.7 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase Nop14 PF04147.12 GBG76628.1 - 0.072 11.3 8.1 0.089 11.0 8.1 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG76628.1 - 1.7 8.0 10.4 2.2 7.6 10.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG76628.1 - 1.8 6.8 7.3 2.2 6.5 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.12 GBG76628.1 - 8.7 4.5 7.4 12 4.1 7.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus APC1_C PF18122.1 GBG76629.1 - 2e-26 93.0 0.0 3.6e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 GBG76629.1 - 1.1e-08 35.7 0.0 3.1e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 GBG76629.1 - 0.00014 22.1 7.1 0.023 15.1 0.0 4.2 3 0 0 3 3 3 2 Proteasome/cyclosome repeat RT_RNaseH_2 PF17919.1 GBG76630.1 - 2.6e-30 104.4 0.0 5.5e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76630.1 - 7.6e-30 103.3 0.0 2.6e-29 101.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SelB-wing_1 PF09105.10 GBG76630.1 - 0.021 14.8 2.3 3.9 7.5 0.6 2.9 2 0 0 2 2 2 0 Elongation factor SelB, winged helix RVT_1 PF00078.27 GBG76630.1 - 0.12 11.9 0.1 0.27 10.7 0.1 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG76630.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.8 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase FRG1 PF06229.12 GBG76630.1 - 2.2 7.9 10.0 0.023 14.4 1.8 1.8 2 0 0 2 2 2 0 FRG1-like domain TerB_C PF15615.6 GBG76630.1 - 3 8.1 13.3 9.5 6.5 13.3 2.0 1 1 0 1 1 1 0 TerB-C domain RT_RNaseH PF17917.1 GBG76631.1 - 1.1e-23 83.5 0.0 2.1e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76631.1 - 1.4e-17 63.6 0.0 2.8e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76631.1 - 9.5e-17 60.9 0.1 7e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG76631.1 - 9.8e-11 41.9 0.0 1.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG76631.1 - 0.0024 18.0 0.0 0.0057 16.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG76632.1 - 0.016 15.4 0.8 0.15 12.3 0.4 2.7 1 1 1 2 2 2 0 Retrotransposon gag protein NolX PF05819.11 GBG76632.1 - 4.9 6.4 8.8 3.9 6.7 5.5 2.1 1 1 2 3 3 3 0 NolX protein RVT_1 PF00078.27 GBG76633.1 - 3e-18 66.2 0.4 1.9e-17 63.5 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76633.1 - 7.3e-07 29.7 0.0 2.1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76633.1 - 2e-06 28.2 0.0 4.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG76633.1 - 3.2e-05 23.7 0.0 7.6e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease HIP1_clath_bdg PF16515.5 GBG76633.1 - 0.00082 19.9 6.3 0.002 18.7 6.3 1.6 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Asp_protease PF09668.10 GBG76633.1 - 0.0027 17.5 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG76633.1 - 0.0066 16.7 0.8 0.077 13.3 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein Spc29 PF17082.5 GBG76633.1 - 0.035 14.0 0.4 0.073 12.9 0.4 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 ATG16 PF08614.11 GBG76633.1 - 0.041 14.1 6.2 1.2 9.3 4.9 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.6 GBG76633.1 - 0.079 13.4 2.3 0.24 11.9 2.3 1.9 1 0 0 1 1 1 0 Snapin/Pallidin DUF421 PF04239.12 GBG76633.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF421) BLOC1_2 PF10046.9 GBG76633.1 - 0.24 11.7 2.0 0.68 10.3 2.0 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GBG76633.1 - 0.38 11.2 1.4 34 5.0 0.0 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 GBG76633.1 - 1.1 7.7 4.2 1.8 7.0 4.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family RT_RNaseH_2 PF17919.1 GBG76634.1 - 7.9e-34 115.7 0.0 1.5e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76634.1 - 3.9e-31 107.5 0.2 7.4e-31 106.5 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76634.1 - 4.6e-28 98.2 0.1 7.4e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76634.1 - 1.3e-15 57.2 0.1 2.7e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76634.1 - 6e-07 29.7 0.3 4.3e-06 26.9 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG76634.1 - 0.12 12.6 0.0 0.55 10.5 0.0 2.2 1 0 0 1 1 1 0 H2C2 zinc finger Headcase PF16002.5 GBG76634.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Headcase protein BAF1_ABF1 PF04684.13 GBG76636.1 - 7.4 5.5 19.9 11 5.0 19.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Integrase_H2C2 PF17921.1 GBG76637.1 - 8.4e-21 73.8 1.7 5.7e-19 68.0 0.3 2.5 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG76637.1 - 5.4e-18 65.3 0.1 1.4e-12 47.9 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG76637.1 - 0.0014 18.8 0.0 0.0053 16.9 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG76637.1 - 0.0023 17.7 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) HAUS6_N PF14661.6 GBG76637.1 - 0.54 9.8 3.5 0.41 10.2 1.2 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus S_100 PF01023.19 GBG76637.1 - 1 9.1 3.5 14 5.5 0.1 2.9 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain RT_RNaseH_2 PF17919.1 GBG76639.1 - 1.2e-53 179.3 0.0 1.8e-29 101.7 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76639.1 - 9.1e-49 164.1 1.7 4.1e-25 88.1 0.4 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76639.1 - 1.8e-39 135.6 2.8 8.6e-19 67.9 0.1 3.4 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76639.1 - 1.3e-10 41.5 0.2 4.3e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG76640.1 - 5.8e-06 26.5 8.4 0.00062 20.0 0.1 3.7 3 0 0 3 3 3 2 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG76640.1 - 0.012 16.2 5.7 0.012 16.2 5.7 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BLOC1_2 PF10046.9 GBG76640.1 - 1.2 9.4 8.2 0.088 13.1 1.7 2.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RT_RNaseH PF17917.1 GBG76641.1 - 1.1e-25 90.0 0.0 1.9e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76641.1 - 2.9e-24 85.8 0.0 6.2e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76641.1 - 2.4e-21 75.6 0.0 4.9e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76641.1 - 4.1e-17 62.5 0.0 9.7e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG76641.1 - 7.1e-12 45.3 0.0 1.8e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG76641.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Phage_GPO PF05929.11 GBG76641.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG76642.1 - 1e-47 160.2 0.0 5.9e-23 80.8 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76642.1 - 1.8e-44 150.3 0.0 5.7e-21 74.8 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76642.1 - 1.6e-33 114.5 4.5 1.3e-15 57.2 0.1 3.7 4 0 0 4 4 4 2 Integrase zinc binding domain rve PF00665.26 GBG76642.1 - 1.4e-21 76.9 0.0 4.3e-09 36.6 0.0 3.2 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG76642.1 - 4.7e-18 65.5 0.0 2.8e-17 63.0 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG76642.1 - 0.00021 21.4 0.6 1 9.6 0.1 2.7 2 0 0 2 2 2 2 H2C2 zinc finger DUF4187 PF13821.6 GBG76642.1 - 0.0003 20.5 10.7 0.12 12.2 2.3 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4187) Lipin_mid PF16876.5 GBG76642.1 - 0.0092 16.1 1.9 1.2 9.3 0.0 3.2 3 0 0 3 3 3 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Integrin_b_cyt PF08725.11 GBG76642.1 - 0.01 15.5 0.2 5.7 6.7 0.0 2.9 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Retrotrans_gag PF03732.17 GBG76642.1 - 0.051 13.9 0.2 0.051 13.9 0.2 4.4 5 0 0 5 5 4 0 Retrotransposon gag protein Cys_rich_CPXG PF14255.6 GBG76642.1 - 0.091 12.7 0.6 22 5.0 0.1 2.6 2 0 0 2 2 2 0 Cysteine-rich CPXCG Vac7 PF12751.7 GBG76643.1 - 0.17 11.3 2.2 0.23 10.8 2.2 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Seryl_tRNA_N PF02403.22 GBG76643.1 - 1 9.7 15.7 2.2 8.6 15.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RPN2_C PF18004.1 GBG76643.1 - 2.4 8.0 13.6 3.4 7.6 13.6 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RT_RNaseH_2 PF17919.1 GBG76644.1 - 6.8e-24 83.8 0.0 1.3e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76644.1 - 6.7e-22 77.8 0.0 1.2e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76644.1 - 7.8e-19 68.1 0.1 2.4e-18 66.4 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76644.1 - 7.2e-17 61.2 1.3 3.1e-16 59.2 0.1 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG76644.1 - 3.6e-10 40.1 0.0 9.1e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG76644.1 - 0.1 12.8 0.1 0.27 11.5 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG76645.1 - 2.2e-56 190.9 0.1 8.6e-30 103.9 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Ammonium_transp PF00909.21 GBG76645.1 - 2.4e-22 79.2 3.0 3.5e-22 78.7 3.0 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family RT_RNaseH_2 PF17919.1 GBG76645.1 - 1.1e-20 73.5 0.0 1.2e-15 57.3 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76645.1 - 1.6e-14 53.7 0.0 5.7e-14 52.0 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76645.1 - 2e-11 44.1 0.0 5.5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG76645.1 - 2.8e-10 39.9 0.0 9e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG76645.1 - 1.5e-09 38.0 0.0 4.2e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG76645.1 - 0.00063 20.0 0.2 0.0027 18.0 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG76645.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG76648.1 - 1.9e-17 63.6 0.0 7.6e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76648.1 - 4.2e-08 33.1 0.0 9.4e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76648.1 - 2.3e-07 31.4 0.0 6.7e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76648.1 - 2.2e-06 28.1 0.0 1.9e-05 25.1 0.0 2.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG76648.1 - 0.0029 17.4 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Ribosomal_L12_N PF16320.5 GBG76648.1 - 0.035 13.8 1.9 0.093 12.4 1.9 1.7 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain RT_RNaseH PF17917.1 GBG76649.1 - 2e-24 85.9 0.1 3.3e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76649.1 - 6.8e-21 74.2 0.0 1.1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76649.1 - 1.6e-18 66.6 0.1 3.9e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76649.1 - 1.6e-09 37.6 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG76649.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 RVP_2 PF08284.11 GBG76650.1 - 1.9e-09 37.4 0.0 9.6e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76650.1 - 1.3e-08 35.4 0.0 3.1e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76650.1 - 3.6e-07 30.7 0.0 1.1e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG76650.1 - 0.00066 19.9 1.0 0.021 15.1 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG76650.1 - 0.004 16.9 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG76650.1 - 0.037 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease TadF PF16964.5 GBG76651.1 - 0.2 11.4 1.2 0.39 10.4 1.2 1.4 1 0 0 1 1 1 0 Putative tight adherence pilin protein F PP2C PF00481.21 GBG76652.1 - 1.6e-35 123.0 0.0 3.2e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C RVT_1 PF00078.27 GBG76652.1 - 2.2e-33 115.7 0.0 3.9e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76652.1 - 8.9e-26 90.2 0.1 2.6e-25 88.8 0.0 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76652.1 - 2.6e-25 88.3 0.0 8.1e-25 86.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG76652.1 - 1.3e-14 54.1 0.0 3.7e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76652.1 - 4.8e-12 46.4 0.0 6.6e-06 26.7 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG76652.1 - 1.2e-09 38.6 0.0 0.00082 19.9 0.0 3.1 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG76652.1 - 1.9e-06 28.0 0.5 0.017 15.4 0.0 3.9 3 0 0 3 3 3 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG76652.1 - 3.6e-05 23.6 0.0 0.39 10.5 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease DUF919 PF06034.11 GBG76652.1 - 0.017 15.0 0.4 0.053 13.4 0.4 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF1758 PF05585.12 GBG76652.1 - 0.02 14.7 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Putative peptidase (DUF1758) AMP-binding_C_2 PF14535.6 GBG76652.1 - 0.14 12.5 0.3 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Lzipper-MIP1 PF14389.6 GBG76652.1 - 3.9 7.8 7.4 7.3 7.0 0.2 3.3 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FAM60A PF15396.6 GBG76653.1 - 6.7 6.7 11.7 1.2 9.1 6.0 2.1 2 0 0 2 2 2 0 Protein Family FAM60A RT_RNaseH_2 PF17919.1 GBG76654.1 - 1.6e-17 63.3 0.0 4.2e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76654.1 - 4.6e-07 30.1 0.0 1.2e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76654.1 - 0.0012 18.4 0.1 0.0023 17.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_lysozyme PF00959.19 GBG76654.1 - 0.19 12.2 3.0 12 6.3 0.1 3.1 2 1 0 2 2 2 0 Phage lysozyme WD40 PF00400.32 GBG76656.1 - 2.4e-08 34.5 1.4 4e-05 24.3 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG76656.1 - 0.00074 19.8 0.0 0.49 10.7 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG76656.1 - 0.094 12.0 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Corazonin PF17308.2 GBG76657.1 - 0.82 10.0 8.4 2 8.8 1.2 2.3 2 0 0 2 2 2 0 Pro-corazonin bZIP_1 PF00170.21 GBG76658.1 - 3.4e-12 46.3 16.2 6.1e-12 45.5 16.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG76658.1 - 2.3e-09 37.2 17.3 5.1e-09 36.1 17.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.18 GBG76658.1 - 0.0062 16.8 2.8 0.035 14.4 2.3 2.4 1 1 1 2 2 2 1 TSC-22/dip/bun family DUF3563 PF12086.8 GBG76658.1 - 0.02 14.6 2.4 0.051 13.3 2.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) GIT_CC PF16559.5 GBG76658.1 - 0.06 13.2 3.7 0.12 12.2 3.7 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Nnf1 PF03980.14 GBG76658.1 - 0.31 11.4 9.6 0.55 10.6 9.6 1.5 1 0 0 1 1 1 0 Nnf1 UPF0242 PF06785.11 GBG76658.1 - 0.34 11.0 9.0 0.46 10.6 9.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TFIIA PF03153.13 GBG76658.1 - 1 9.3 10.8 1.4 8.8 10.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4554 PF15091.6 GBG76658.1 - 5.6 5.7 6.4 7.1 5.4 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DHHC PF01529.20 GBG76659.1 - 0.00029 21.0 0.0 0.0005 20.2 0.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase LAP1C PF05609.12 GBG76659.1 - 0.0023 17.1 23.1 0.0032 16.6 23.1 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 GBG76659.1 - 0.12 11.0 18.8 0.15 10.6 18.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF2956 PF11169.8 GBG76659.1 - 0.84 9.9 0.0 0.84 9.9 0.0 4.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2956) DUF4551 PF15087.6 GBG76659.1 - 2.4 6.9 18.7 3.2 6.5 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 GBG76660.1 - 0.53 8.5 11.2 0.62 8.3 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein 3A PF00803.18 GBG76661.1 - 0.018 14.3 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family DHHC PF01529.20 GBG76662.1 - 1.6e-11 44.5 10.3 1.6e-11 44.5 10.3 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 GBG76662.1 - 0.23 11.6 4.7 0.34 11.1 4.7 1.2 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger HTH_Tnp_Tc5 PF03221.16 GBG76663.1 - 3.6e-12 46.1 0.3 8.6e-12 44.9 0.3 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 GBG76663.1 - 5e-07 29.5 0.0 9.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 GBG76663.1 - 5.5e-05 23.2 0.0 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 GBG76663.1 - 0.00073 19.8 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 GBG76663.1 - 0.0016 18.5 0.2 0.0044 17.0 0.2 1.8 1 0 0 1 1 1 1 Winged helix-turn helix CENP-B_N PF04218.13 GBG76663.1 - 0.021 14.4 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 GBG76663.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain MerR PF00376.23 GBG76663.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein MerR_1 PF13411.6 GBG76663.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein GDA1_CD39 PF01150.17 GBG76667.1 - 2.3e-56 191.3 0.0 7.5e-39 133.6 0.0 3.0 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Myb_DNA-bind_4 PF13837.6 GBG76668.1 - 3.3e-07 30.6 2.3 5.8e-07 29.8 2.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG76668.1 - 0.031 14.6 1.5 0.063 13.6 1.5 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG76668.1 - 0.031 14.3 3.1 0.084 13.0 2.3 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Actin PF00022.19 GBG76668.1 - 0.12 11.0 0.1 0.17 10.4 0.1 1.2 1 0 0 1 1 1 0 Actin Saf_2TM PF18303.1 GBG76669.1 - 0.1 12.2 0.2 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain GspL_C PF12693.7 GBG76669.1 - 0.22 11.3 1.4 0.31 10.9 1.4 1.1 1 0 0 1 1 1 0 GspL periplasmic domain Retrotrans_gag PF03732.17 GBG76674.1 - 0.0018 18.5 3.8 0.061 13.6 0.1 3.7 4 0 0 4 4 4 2 Retrotransposon gag protein zf-CCHC PF00098.23 GBG76675.1 - 1.9e-05 24.5 2.9 4.3e-05 23.4 2.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG76675.1 - 5.6e-05 22.9 5.2 0.00039 20.2 0.8 3.0 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG76675.1 - 0.029 14.4 0.7 0.12 12.4 0.7 2.1 1 0 0 1 1 1 0 Zinc knuckle Menin PF05053.13 GBG76675.1 - 0.53 8.6 9.4 0.64 8.3 9.4 1.1 1 0 0 1 1 1 0 Menin Ins_P5_2-kin PF06090.12 GBG76676.1 - 1.9e-70 237.9 0.0 4.9e-66 223.4 0.0 2.5 2 0 0 2 2 2 2 Inositol-pentakisphosphate 2-kinase RT_RNaseH_2 PF17919.1 GBG76676.1 - 2e-33 114.4 0.0 4e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76676.1 - 7.1e-31 106.6 0.1 1.5e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76676.1 - 3.2e-29 102.0 0.0 1.1e-28 100.3 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76676.1 - 1.7e-14 54.0 0.1 1.3e-13 51.2 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG76676.1 - 7.4e-09 35.6 0.6 1.8e-08 34.4 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain P_proprotein PF01483.20 GBG76680.1 - 1.3e-20 73.2 0.1 2.9e-09 36.8 0.0 2.9 2 0 0 2 2 2 2 Proprotein convertase P-domain RT_RNaseH_2 PF17919.1 GBG76680.1 - 2.9e-11 43.3 0.0 7.4e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76680.1 - 4.6e-11 42.7 0.4 1.8e-06 27.6 0.1 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76680.1 - 3.4e-07 30.1 0.0 1.1e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76680.1 - 3.6e-07 30.7 0.0 2.4e-06 28.1 0.0 2.4 3 0 0 3 3 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76680.1 - 8.6e-06 26.2 0.0 9.1e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG76680.1 - 0.00036 20.8 0.0 0.00092 19.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG76680.1 - 0.0052 16.6 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG76680.1 - 0.0064 16.7 0.2 0.032 14.5 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein SpoIIP PF07454.11 GBG76680.1 - 2.5 7.5 24.3 1.9 7.9 2.3 3.2 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) Plasmodium_Vir PF05795.11 GBG76680.1 - 4.7 6.5 10.8 2.4 7.5 0.8 2.7 3 0 0 3 3 3 0 Plasmodium vivax Vir protein Complex1_LYR PF05347.15 GBG76681.1 - 7.8e-06 25.9 2.2 1.7e-05 24.7 2.2 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) XRN_M PF17846.1 GBG76681.1 - 0.0013 17.7 1.0 0.0086 15.1 0.0 2.2 2 0 0 2 2 2 1 Xrn1 helical domain Retrotrans_gag PF03732.17 GBG76681.1 - 0.026 14.8 2.1 0.062 13.6 0.0 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein DUF2490 PF10677.9 GBG76681.1 - 1 9.3 5.8 0.59 10.0 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2490) DUF1192 PF06698.11 GBG76682.1 - 0.029 14.4 0.1 0.087 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4164 PF13747.6 GBG76682.1 - 0.64 10.3 4.4 5.5 7.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) RVT_1 PF00078.27 GBG76683.1 - 5e-28 98.1 0.0 8.3e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76683.1 - 7e-16 58.1 0.1 1.8e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG76683.1 - 4.9e-12 46.1 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG76683.1 - 1.5e-05 25.1 0.1 4.5e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 GBG76684.1 - 1.1e-33 116.6 0.1 2.5e-33 115.5 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76684.1 - 1.4e-20 73.2 0.0 4e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG76684.1 - 1.6e-08 34.4 0.0 3.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG76684.1 - 1.3e-07 31.8 0.0 4.7e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG76684.1 - 2.6e-05 24.0 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG76684.1 - 5.3e-05 23.8 0.0 0.00026 21.6 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76684.1 - 0.00011 22.7 0.0 0.00036 21.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease PLDc_2 PF13091.6 GBG76684.1 - 0.00011 22.1 0.0 0.91 9.4 0.0 3.5 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 GBG76684.1 - 0.019 15.2 0.2 0.042 14.0 0.2 1.7 1 0 0 1 1 1 0 Phospholipase D Active site motif UPF0184 PF03670.13 GBG76684.1 - 0.14 12.6 1.6 14 6.2 0.2 3.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Trans_reg_C PF00486.28 GBG76684.1 - 0.17 12.0 0.6 0.47 10.6 0.6 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal CDC45 PF02724.14 GBG76685.1 - 6.5e-06 24.7 5.3 6.5e-06 24.7 5.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Na_trans_assoc PF06512.13 GBG76685.1 - 0.87 9.8 14.2 1.2 9.4 14.2 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG76685.1 - 6.8 4.8 29.7 8.5 4.5 29.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3490 PF11995.8 GBG76687.1 - 0.037 13.9 0.4 0.065 13.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Asp_protease_2 PF13650.6 GBG76688.1 - 0.049 14.3 0.0 0.093 13.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG76688.1 - 0.054 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG76688.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease XG_FTase PF03254.13 GBG76690.1 - 2.1e-79 267.4 0.1 9.3e-27 93.8 0.0 3.0 2 1 1 3 3 3 3 Xyloglucan fucosyltransferase Rab5ip PF07019.12 GBG76691.1 - 3.5e-14 53.1 16.0 4.1e-14 52.9 16.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF4231 PF14015.6 GBG76691.1 - 0.059 13.9 0.2 0.076 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) PrgI PF12666.7 GBG76691.1 - 1.9 9.3 6.3 0.66 10.7 3.5 1.6 1 1 1 2 2 2 0 PrgI family protein Integrase_H2C2 PF17921.1 GBG76692.1 - 1.9e-05 24.7 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Angiomotin_C PF12240.8 GBG76692.1 - 0.043 13.4 0.2 0.12 11.9 0.2 1.7 1 0 0 1 1 1 0 Angiomotin C terminal Phos_pyr_kin PF08543.12 GBG76693.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase FERM_f0 PF16511.5 GBG76694.1 - 5.8 7.3 14.3 35 4.8 0.5 4.9 1 1 6 7 7 7 0 N-terminal or F0 domain of Talin-head FERM DUF4436 PF14494.6 GBG76695.1 - 0.041 13.2 0.1 0.1 11.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4436) YabA PF06156.13 GBG76695.1 - 1.5 9.5 13.6 7.6 7.2 0.3 3.5 2 1 2 4 4 4 0 Initiation control protein YabA APG6_N PF17675.1 GBG76695.1 - 3.3 8.2 18.6 3.8 8.1 0.3 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region bZIP_1 PF00170.21 GBG76695.1 - 3.6 7.8 12.5 9.1 6.5 0.1 3.9 4 2 0 4 4 4 0 bZIP transcription factor Exonuc_VII_S PF02609.16 GBG76696.1 - 0.00068 19.6 0.3 0.0012 18.8 0.3 1.4 1 1 0 1 1 1 1 Exonuclease VII small subunit HxlR PF01638.17 GBG76696.1 - 0.0019 18.0 0.1 0.0029 17.4 0.1 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PA26 PF04636.13 GBG76697.1 - 1 8.2 7.5 1.1 8.1 7.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Sec62 PF03839.16 GBG76697.1 - 5.9 6.3 6.8 6.2 6.3 6.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.6 GBG76697.1 - 8.1 5.7 12.9 9.9 5.4 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 GBG76698.1 - 0.00025 21.6 4.4 0.0015 19.1 2.6 2.4 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 GBG76698.1 - 0.0099 16.0 2.6 0.16 12.0 1.0 2.4 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 GBG76698.1 - 0.011 16.2 0.7 0.22 12.0 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 GBG76698.1 - 0.034 13.9 1.4 0.52 10.1 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4618 PF15397.6 GBG76698.1 - 0.035 13.5 2.1 0.088 12.2 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) BLOC1_2 PF10046.9 GBG76698.1 - 0.073 13.4 2.1 1 9.7 0.7 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 GBG76698.1 - 0.13 12.9 5.8 12 6.6 3.8 3.5 3 1 0 3 3 3 0 SlyX SPARC_Ca_bdg PF10591.9 GBG76698.1 - 0.16 12.3 1.9 0.14 12.4 0.3 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region FUSC PF04632.12 GBG76698.1 - 0.52 8.8 4.3 0.69 8.4 4.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlxA PF14282.6 GBG76698.1 - 1 9.4 5.9 13 5.8 1.2 2.6 1 1 1 2 2 2 0 FlxA-like protein LPP PF04728.13 GBG76698.1 - 1.8 9.0 6.0 3.3 8.2 0.1 2.8 3 0 0 3 3 2 0 Lipoprotein leucine-zipper ATG16 PF08614.11 GBG76698.1 - 5.2 7.3 11.2 5.4 7.2 5.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 GBG76698.1 - 7.2 7.0 8.2 17 5.8 3.6 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF659 PF04937.15 GBG76699.1 - 8.8e-13 48.4 0.0 1.7e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Nucleotid_trans PF03407.16 GBG76700.1 - 1.3e-23 84.1 0.0 7.8e-23 81.6 0.0 2.2 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Glyco_tranf_2_3 PF13641.6 GBG76700.1 - 0.00063 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF2076 PF09849.9 GBG76700.1 - 0.43 10.6 2.2 0.78 9.7 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Mrpl_C PF18502.1 GBG76701.1 - 8.8 6.7 13.5 3.6 7.9 1.7 3.3 3 1 1 4 4 4 0 54S ribosomal protein L8 C-terminal domain Pkinase_Tyr PF07714.17 GBG76702.1 - 2.8e-57 194.0 0.0 4.7e-57 193.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76702.1 - 2.9e-37 128.5 0.0 5.8e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG76702.1 - 3.4e-21 75.2 0.0 1.1e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76702.1 - 3.1e-13 49.9 0.0 1e-12 48.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Kinase-like PF14531.6 GBG76702.1 - 6.3e-06 25.7 0.1 1.6e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RVT_1 PF00078.27 GBG76702.1 - 0.0098 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Matrilin_ccoil PF10393.9 GBG76702.1 - 0.01 15.7 0.4 0.028 14.3 0.4 1.8 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin SlyX PF04102.12 GBG76702.1 - 0.033 14.8 1.0 0.033 14.8 1.0 3.0 3 0 0 3 3 3 0 SlyX DUF2730 PF10805.8 GBG76702.1 - 0.13 12.4 1.6 1.9 8.6 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Retrotrans_gag PF03732.17 GBG76703.1 - 0.021 15.1 4.4 0.45 10.8 0.0 3.8 3 1 1 4 4 4 0 Retrotransposon gag protein DUF16 PF01519.16 GBG76703.1 - 0.77 10.3 9.1 0.36 11.3 0.8 3.5 2 1 0 3 3 3 0 Protein of unknown function DUF16 CENP-X PF09415.10 GBG76703.1 - 6 7.3 14.2 1.4 9.3 3.1 2.8 1 1 1 2 2 2 0 CENP-S associating Centromere protein X AAA_13 PF13166.6 GBG76704.1 - 0.00092 18.0 9.8 0.00092 18.0 9.8 7.0 3 1 3 8 8 8 2 AAA domain DUF2716 PF10898.8 GBG76704.1 - 2.9 8.2 5.3 55 4.1 0.3 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2716) RT_RNaseH PF17917.1 GBG76705.1 - 8.6e-23 80.6 0.1 1.9e-22 79.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76705.1 - 8.6e-22 77.1 0.1 2.2e-21 75.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76705.1 - 1.8e-16 60.0 0.1 3.7e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76705.1 - 1.2e-13 51.1 0.1 3.2e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76705.1 - 2.6e-12 47.0 0.0 7.8e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG76705.1 - 0.0037 17.5 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG76705.1 - 0.0055 16.5 0.0 0.04 13.7 0.0 2.3 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76705.1 - 0.009 16.6 0.0 0.027 15.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76705.1 - 0.092 13.3 0.3 0.31 11.6 0.1 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG76705.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF2862 PF11061.8 GBG76705.1 - 0.16 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) RT_RNaseH_2 PF17919.1 GBG76707.1 - 4.5e-32 110.1 0.0 1.1e-31 108.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76707.1 - 1.5e-30 106.4 0.2 2.2e-30 105.8 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76707.1 - 1.5e-30 105.6 0.4 3.5e-30 104.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76707.1 - 2.2e-16 59.7 0.1 4.8e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76707.1 - 1e-11 45.1 0.0 2.9e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DUF3327 PF11806.8 GBG76707.1 - 0.084 13.6 0.9 0.45 11.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3327) ANAPC_CDC26 PF10471.9 GBG76707.1 - 0.12 13.2 6.9 0.12 13.2 2.7 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 IceA2 PF05862.11 GBG76707.1 - 0.13 12.2 0.6 0.3 11.1 0.6 1.5 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein PTEN_C2 PF10409.9 GBG76708.1 - 4e-08 33.1 0.0 6.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DUF3020 PF11223.8 GBG76708.1 - 0.084 13.4 0.2 0.084 13.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) DUF4844 PF16133.5 GBG76708.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) RT_RNaseH_2 PF17919.1 GBG76709.1 - 2.5e-24 85.2 0.0 4.7e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76709.1 - 2.5e-20 72.7 0.0 6.3e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76709.1 - 5.1e-16 58.9 0.0 1.2e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG76709.1 - 1.5e-14 53.8 0.0 3.6e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG76709.1 - 0.01 15.6 0.0 0.037 13.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Asp_protease_2 PF13650.6 GBG76709.1 - 0.018 15.7 0.0 0.046 14.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG76709.1 - 0.043 14.4 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease PBS_linker_poly PF00427.21 GBG76709.1 - 0.08 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide RVP PF00077.20 GBG76709.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease NB-ARC PF00931.22 GBG76711.1 - 4.8e-37 127.5 0.1 8.4e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain LRR_8 PF13855.6 GBG76711.1 - 6.4e-11 41.9 0.3 0.0046 16.7 0.0 4.5 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 GBG76711.1 - 6.7e-11 42.3 6.9 0.011 16.1 0.3 5.8 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) NACHT PF05729.12 GBG76711.1 - 0.0022 17.9 0.1 0.016 15.1 0.1 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 GBG76711.1 - 0.017 15.4 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG76711.1 - 0.025 15.1 0.0 0.078 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain LRR_1 PF00560.33 GBG76711.1 - 0.035 14.6 21.8 2.6 8.9 0.1 8.3 9 0 0 9 9 9 0 Leucine Rich Repeat DsrH PF04077.12 GBG76712.1 - 0.00044 20.3 0.5 92 3.3 0.0 6.1 1 1 8 9 9 9 0 DsrH like protein SeleniumBinding PF11524.8 GBG76712.1 - 0.0062 17.0 19.0 20 5.7 0.2 7.6 1 1 5 6 6 6 2 Selenium binding protein Ribosomal_L6 PF00347.23 GBG76712.1 - 0.29 11.8 24.1 2.8 8.7 1.3 4.8 3 2 2 5 5 5 0 Ribosomal protein L6 XendoU PF09412.10 GBG76712.1 - 0.72 9.0 11.4 4.3 6.5 0.2 4.0 1 1 4 5 5 5 0 Endoribonuclease XendoU Neisseria_TspB PF05616.13 GBG76712.1 - 2.1 6.7 8.0 7 5.0 0.3 3.6 1 1 2 4 4 4 0 Neisseria meningitidis TspB protein Pkinase PF00069.25 GBG76714.1 - 1.6e-74 250.6 0.0 7.8e-59 199.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76714.1 - 1.6e-32 112.8 0.0 2.2e-27 96.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GBG76714.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GBG76714.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 GBG76715.1 - 6.8e-69 232.2 0.0 8.6e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76715.1 - 3.4e-30 105.2 0.0 4.6e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG76715.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GBG76715.1 - 0.15 11.7 0.0 0.33 10.5 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase V-SNARE PF05008.15 GBG76716.1 - 5.7e-26 90.7 0.7 5.7e-26 90.7 0.7 3.2 3 1 1 4 4 4 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 GBG76716.1 - 5.3e-22 77.9 10.8 3.3e-21 75.4 4.1 3.4 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GBG76716.1 - 4e-07 29.9 1.0 1.9e-06 27.7 0.3 2.4 1 1 2 3 3 3 1 Sec20 IFT57 PF10498.9 GBG76716.1 - 0.0049 15.9 3.8 0.046 12.7 0.8 2.1 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 Metal_resist PF13801.6 GBG76716.1 - 0.025 14.8 0.9 0.025 14.8 0.9 2.1 2 0 0 2 2 2 0 Heavy-metal resistance Fusion_gly PF00523.18 GBG76716.1 - 0.064 11.5 2.9 0.41 8.8 0.2 2.5 1 1 2 3 3 3 0 Fusion glycoprotein F0 SNARE PF05739.19 GBG76716.1 - 0.074 13.1 1.7 1.5 8.9 0.5 2.6 2 0 0 2 2 2 0 SNARE domain DUF5082 PF16888.5 GBG76716.1 - 0.089 13.1 3.3 0.53 10.6 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Uds1 PF15456.6 GBG76716.1 - 0.093 12.9 6.3 0.062 13.5 4.0 2.0 1 1 0 1 1 1 0 Up-regulated During Septation OppC_N PF12911.7 GBG76716.1 - 0.1 12.6 4.3 0.19 11.7 4.3 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4407 PF14362.6 GBG76716.1 - 0.12 11.7 10.2 0.44 9.9 10.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GBG76716.1 - 0.24 10.9 10.6 2.8 7.4 10.6 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4570 PF15134.6 GBG76716.1 - 0.44 10.6 8.5 0.082 12.9 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) PKK PF12474.8 GBG76716.1 - 0.56 10.3 5.6 0.99 9.5 5.6 1.5 1 0 0 1 1 1 0 Polo kinase kinase Spc7 PF08317.11 GBG76716.1 - 0.69 8.7 10.6 1.3 7.8 2.5 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Cnn_1N PF07989.11 GBG76716.1 - 0.81 9.9 7.0 0.28 11.4 0.7 2.8 2 2 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF745 PF05335.13 GBG76716.1 - 0.9 9.2 8.2 3.6 7.3 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Sec8_exocyst PF04048.14 GBG76716.1 - 1.2 9.0 7.6 11 5.9 0.6 3.4 2 1 2 4 4 4 0 Sec8 exocyst complex component specific domain Snapin_Pallidin PF14712.6 GBG76716.1 - 1.5 9.3 8.9 4.7 7.7 1.0 2.7 2 2 0 2 2 2 0 Snapin/Pallidin BST2 PF16716.5 GBG76716.1 - 1.9 9.1 8.3 0.76 10.4 1.1 2.7 2 1 0 3 3 3 0 Bone marrow stromal antigen 2 XhlA PF10779.9 GBG76716.1 - 4.2 7.6 9.7 4.8 7.5 0.1 3.7 4 0 0 4 4 4 0 Haemolysin XhlA Synaptobrevin PF00957.21 GBG76716.1 - 8.2 6.3 8.0 1.7 8.5 1.6 2.5 2 1 0 2 2 2 0 Synaptobrevin Integrase_H2C2 PF17921.1 GBG76717.1 - 3.3e-14 52.7 0.2 1.7e-13 50.5 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG76717.1 - 0.00012 22.5 0.0 0.00029 21.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76717.1 - 0.0067 17.0 0.0 0.017 15.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Glutaredoxin PF00462.24 GBG76718.1 - 2.3e-17 63.0 0.0 4.5e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 GBG76718.1 - 0.0026 18.0 0.0 0.0099 16.2 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GBG76718.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GIY-YIG PF01541.24 GBG76718.1 - 0.084 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain SH3BGR PF04908.15 GBG76718.1 - 0.21 11.8 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein GDI PF00996.18 GBG76719.1 - 5.7e-06 25.1 0.1 5.8e-06 25.1 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Retrotrans_gag PF03732.17 GBG76720.1 - 0.0062 16.8 0.3 0.017 15.4 0.3 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein TPR_2 PF07719.17 GBG76720.1 - 0.047 13.8 8.0 0.43 10.8 0.0 5.8 7 1 0 7 7 7 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 GBG76721.1 - 0.0063 16.8 0.3 0.017 15.4 0.3 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein TPR_2 PF07719.17 GBG76721.1 - 0.048 13.8 8.0 0.43 10.8 0.0 5.8 7 1 0 7 7 7 0 Tetratricopeptide repeat DnaJ_CXXCXGXG PF00684.19 GBG76722.1 - 1e-05 25.8 8.2 1e-05 25.8 8.2 3.3 2 1 1 3 3 3 2 DnaJ central domain Anti-TRAP PF15777.5 GBG76722.1 - 0.0083 16.1 0.4 0.0083 16.1 0.4 4.6 3 1 2 5 5 5 1 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 GBG76722.1 - 0.066 13.6 0.7 0.066 13.6 0.7 3.3 1 1 1 3 3 3 0 Restriction alleviation protein Lar PHD_4 PF16866.5 GBG76722.1 - 7.7 6.7 8.4 0.53 10.4 0.5 2.9 1 1 2 3 3 3 0 PHD-finger NUFIP1 PF10453.9 GBG76723.1 - 5.4e-11 42.2 4.3 5.4e-11 42.2 4.3 2.4 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 GBG76723.1 - 6.8e-05 23.0 1.3 6.8e-05 23.0 1.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf_CCCH_4 PF18345.1 GBG76723.1 - 0.00016 21.6 3.5 0.00042 20.3 3.5 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GBG76723.1 - 0.00046 20.0 4.7 0.001 18.9 4.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-met PF12874.7 GBG76723.1 - 0.00049 20.4 1.2 0.0015 18.8 1.2 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 GBG76723.1 - 0.0022 18.4 2.0 0.012 16.1 2.0 2.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GBG76723.1 - 0.0036 18.0 2.1 0.044 14.6 0.5 2.9 1 1 1 2 2 2 1 C2H2-type zinc finger zf-CCCH_4 PF18044.1 GBG76723.1 - 0.023 14.5 5.1 0.088 12.6 5.1 2.1 1 0 0 1 1 1 0 CCCH-type zinc finger Torus PF16131.5 GBG76723.1 - 0.13 13.0 6.4 0.21 12.3 0.6 3.0 2 0 0 2 2 2 0 Torus domain zf-CCHC PF00098.23 GBG76724.1 - 9.9e-06 25.4 2.2 1.7e-05 24.7 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG76724.1 - 0.00051 19.8 6.8 0.00086 19.1 6.8 1.3 1 0 0 1 1 1 1 Zinc knuckle FAD_binding_3 PF01494.19 GBG76725.1 - 1.7e-22 80.2 0.0 1.1e-21 77.5 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GBG76725.1 - 2.2e-07 30.8 0.2 4.1e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG76725.1 - 1.9e-06 27.3 0.4 3.1e-06 26.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GBG76725.1 - 5.3e-06 26.6 1.5 1.7e-05 24.9 1.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GBG76725.1 - 0.00083 18.7 0.2 0.0013 18.0 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GBG76725.1 - 0.0044 16.1 0.4 0.0072 15.4 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 GBG76725.1 - 0.019 15.5 0.7 0.046 14.3 0.7 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG76725.1 - 0.02 14.2 3.1 0.032 13.5 3.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG76725.1 - 0.046 12.4 1.8 0.069 11.8 1.8 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 GBG76725.1 - 0.058 12.6 1.7 0.098 11.9 1.7 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 GBG76725.1 - 0.13 11.6 4.1 0.24 10.7 4.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GBG76725.1 - 0.17 10.9 3.1 0.26 10.4 3.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 GBG76725.1 - 0.26 10.1 1.3 0.39 9.5 1.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 GBG76725.1 - 3 7.1 8.9 0.033 13.6 1.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase RIO1 PF01163.22 GBG76726.1 - 9.7e-49 165.5 0.7 8.6e-48 162.4 0.2 2.1 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 GBG76726.1 - 2.1e-33 114.4 0.8 6.1e-33 112.9 0.5 1.9 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 GBG76726.1 - 4e-09 36.7 0.6 0.00012 22.1 0.2 3.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GBG76726.1 - 6.2e-06 25.7 0.9 0.031 13.6 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GBG76726.1 - 0.017 14.5 0.1 0.065 12.5 0.0 1.8 2 0 0 2 2 2 0 Kinase-like TFIIF_beta PF02270.15 GBG76726.1 - 0.062 13.5 0.0 7.1 6.8 0.0 2.4 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain DUF3196 PF11428.8 GBG76726.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) Pkinase PF00069.25 GBG76726.1 - 0.37 10.1 1.2 1.2 8.4 1.2 1.8 1 1 0 1 1 1 0 Protein kinase domain Thioredoxin PF00085.20 GBG76727.1 - 1.3e-39 134.3 0.0 1.2e-16 60.5 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin AhpC-TSA PF00578.21 GBG76727.1 - 1.3e-10 41.3 0.1 0.0021 17.9 0.0 3.5 3 0 0 3 3 3 3 AhpC/TSA family Thioredoxin_2 PF13098.6 GBG76727.1 - 4.1e-10 40.1 0.3 0.0049 17.3 0.1 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.10 GBG76727.1 - 3.7e-08 33.2 0.0 0.047 13.4 0.0 3.6 3 1 0 3 3 3 3 Redoxin Thioredoxin_8 PF13905.6 GBG76727.1 - 3.6e-05 24.0 0.0 4.9 7.5 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 GBG76727.1 - 0.00016 21.8 0.8 3.3 8.0 0.0 4.5 3 1 0 3 3 3 2 Thioredoxin-like UPF0515 PF15135.6 GBG76727.1 - 0.0012 18.2 0.2 0.0012 18.2 0.2 1.6 2 0 0 2 2 2 1 Uncharacterised protein UPF0515 TraF PF13728.6 GBG76727.1 - 0.0015 18.4 14.4 0.028 14.2 0.0 4.2 5 0 0 5 5 5 3 F plasmid transfer operon protein SpoIIP PF07454.11 GBG76727.1 - 0.098 12.1 0.1 0.098 12.1 0.1 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) zf_PR_Knuckle PF18445.1 GBG76727.1 - 0.1 12.5 0.5 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 PR zinc knuckle motif OST3_OST6 PF04756.13 GBG76727.1 - 0.11 11.9 0.3 2.4 7.5 0.0 3.0 5 0 0 5 5 5 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 GBG76727.1 - 0.12 12.6 5.0 28 5.0 0.0 4.6 4 1 1 5 5 4 0 Glutaredoxin AAA_11 PF13086.6 GBG76727.1 - 3.1 7.5 12.8 3.5 7.3 3.9 2.5 3 0 0 3 3 3 0 AAA domain DUF2229 PF09989.9 GBG76727.1 - 9.3 5.8 9.2 6.1 6.4 0.1 2.8 3 0 0 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) Pkinase PF00069.25 GBG76729.1 - 5.3e-72 242.3 0.0 7.3e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG76729.1 - 9e-34 116.9 0.0 2.1e-33 115.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GBG76729.1 - 2.8e-05 23.6 0.2 4.5e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GBG76729.1 - 0.00096 18.6 0.1 0.0044 16.4 0.0 2.1 2 1 1 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 GBG76729.1 - 0.0014 17.6 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GBG76729.1 - 0.019 14.9 2.3 0.021 14.8 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family PPR PF01535.20 GBG76730.1 - 4.6e-125 399.5 54.4 2.8e-07 30.3 0.1 21.4 21 0 0 21 21 21 21 PPR repeat PPR_2 PF13041.6 GBG76730.1 - 6.8e-114 372.0 25.9 5.8e-14 52.0 0.0 18.2 11 7 9 20 20 20 16 PPR repeat family PPR_1 PF12854.7 GBG76730.1 - 1.2e-106 348.0 27.3 2.4e-08 33.5 0.0 21.1 21 0 0 21 21 21 19 PPR repeat PPR_3 PF13812.6 GBG76730.1 - 1.3e-64 214.1 0.0 3.3e-08 33.5 0.0 12.7 8 5 5 13 13 13 13 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG76730.1 - 4.3e-26 91.6 11.3 6.4e-06 25.7 0.0 7.0 5 2 2 7 7 7 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GBG76730.1 - 7.1e-12 45.1 27.7 0.19 12.6 0.0 13.2 15 2 2 17 17 13 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG76730.1 - 3.1e-10 39.4 10.0 0.69 10.1 0.0 10.9 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG76730.1 - 7.7e-10 39.1 3.1 25 5.5 0.0 9.3 8 1 2 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG76730.1 - 1.8e-06 28.5 12.8 3.2 8.5 0.5 9.8 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_4 PF07721.14 GBG76730.1 - 1.7e-05 25.0 22.7 5.4 7.9 0.0 10.2 11 0 0 11 11 10 1 Tetratricopeptide repeat Clathrin PF00637.20 GBG76730.1 - 0.0025 17.7 0.0 1.6 8.6 0.0 4.1 3 0 0 3 3 3 1 Region in Clathrin and VPS MRP-S27 PF10037.9 GBG76730.1 - 0.15 10.9 0.0 9.9 4.9 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_8 PF13181.6 GBG76730.1 - 0.16 12.2 3.2 17 5.9 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG76730.1 - 0.28 11.5 14.9 26 5.2 0.0 7.9 9 1 0 9 9 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG76730.1 - 0.9 9.8 20.2 11 6.4 0.0 9.2 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG76730.1 - 8.5 7.2 10.3 5.8 7.8 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 GBG76731.1 - 9.4e-17 61.4 0.0 2.4e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 GBG76731.1 - 9.9e-16 57.9 10.8 0.00011 22.9 0.0 7.1 6 0 0 6 6 6 4 WD domain, G-beta repeat GATase_4 PF13230.6 GBG76731.1 - 1.1e-12 47.5 0.0 2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 GBG76731.1 - 7.1e-08 32.7 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain M20_dimer PF07687.14 GBG76731.1 - 9.9e-06 25.4 0.0 3.2e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain WD40_like PF17005.5 GBG76731.1 - 1.4e-05 24.6 0.0 0.00067 19.1 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 GBG76731.1 - 0.00017 20.4 5.2 0.14 10.8 0.2 4.1 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Aldedh PF00171.22 GBG76733.1 - 7.9e-174 578.5 0.0 8.9e-174 578.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GBG76733.1 - 0.02 14.3 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) RVT_1 PF00078.27 GBG76734.1 - 2.4e-29 102.4 0.1 4.2e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76734.1 - 9.4e-22 77.3 0.0 2e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76734.1 - 4.9e-14 52.2 0.8 1.1e-13 51.0 0.8 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG76734.1 - 1.7e-13 50.4 0.0 4.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76734.1 - 2.8e-10 40.4 0.0 6.6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG76734.1 - 0.00054 20.1 0.3 0.0013 18.9 0.3 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Topoisom_bac PF01131.20 GBG76735.1 - 2.5e-112 375.9 0.0 3.3e-112 375.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 GBG76735.1 - 2.8e-22 78.9 0.0 6e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Toprim domain SWIB PF02201.18 GBG76735.1 - 1.4e-21 76.2 0.0 3.5e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Toprim_C_rpt PF13368.6 GBG76735.1 - 8.8e-21 73.7 0.0 5.2e-11 42.4 0.0 2.9 1 1 1 2 2 2 2 Topoisomerase C-terminal repeat zf-C4_Topoisom PF01396.19 GBG76735.1 - 3e-12 46.1 0.9 8.4e-12 44.7 0.9 1.8 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Toprim_4 PF13662.6 GBG76735.1 - 0.013 15.9 0.0 0.05 14.1 0.0 2.1 2 0 0 2 2 2 0 Toprim domain AT_hook PF02178.19 GBG76735.1 - 5.8 7.1 8.4 43 4.5 8.4 2.6 1 0 0 1 1 1 0 AT hook motif UCH PF00443.29 GBG76736.1 - 1.3e-76 257.5 0.0 1.8e-76 257.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GBG76736.1 - 3.7e-23 81.9 0.2 9.5e-23 80.6 0.2 1.7 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 GBG76736.1 - 1e-15 58.2 0.1 2e-07 30.9 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 GBG76736.1 - 1.1e-06 28.5 0.0 0.0002 21.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal Ubiquitin_3 PF14836.6 GBG76736.1 - 0.0073 16.3 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain UN_NPL4 PF11543.8 GBG76736.1 - 0.008 16.6 0.1 2.5 8.6 0.1 2.5 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 RA PF00788.23 GBG76736.1 - 0.04 14.5 0.2 19 5.9 0.0 2.8 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Ubiquitin_2 PF14560.6 GBG76736.1 - 0.15 12.6 0.1 0.34 11.4 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain RT_RNaseH_2 PF17919.1 GBG76737.1 - 6.3e-06 26.2 0.1 2.7e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76737.1 - 0.00021 20.9 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76738.1 - 6.3e-06 26.1 0.1 2.7e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76738.1 - 0.00021 20.9 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Toxin_19 PF08088.12 GBG76739.1 - 0.37 10.9 5.7 14 5.9 0.5 3.1 3 0 0 3 3 3 0 Conotoxin I-superfamily Mcp5_PH PF12814.7 GBG76740.1 - 0.025 14.7 0.2 0.048 13.8 0.2 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology DUF5387 PF17361.2 GBG76743.1 - 0.0056 16.4 0.5 0.014 15.1 0.5 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5387) C2 PF00168.30 GBG76744.1 - 1e-11 45.0 0.0 1.6e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain LysM PF01476.20 GBG76744.1 - 7.2e-10 38.8 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 LysM domain LysM PF01476.20 GBG76745.1 - 6.5e-10 38.9 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 LysM domain C2 PF00168.30 GBG76745.1 - 2.9e-07 30.7 0.0 5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain YjbE PF11106.8 GBG76745.1 - 0.93 9.8 4.3 2 8.7 4.3 1.6 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE zf-CCHC PF00098.23 GBG76746.1 - 0.00059 19.8 3.2 0.00059 19.8 3.2 2.7 2 0 0 2 2 2 1 Zinc knuckle VIR_N PF15912.5 GBG76746.1 - 0.017 14.8 1.1 0.017 14.8 1.1 2.7 4 0 0 4 4 4 0 Virilizer, N-terminal MbeD_MobD PF04899.12 GBG76746.1 - 1.1 9.5 9.4 0.23 11.6 0.4 3.0 3 0 0 3 3 3 0 MbeD/MobD like WD40_alt PF14077.6 GBG76746.1 - 1.3 8.9 7.6 0.27 11.1 0.2 3.6 3 0 0 3 3 3 0 Alternative WD40 repeat motif RVT_1 PF00078.27 GBG76747.1 - 3.7e-26 92.0 0.0 1.6e-25 89.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76747.1 - 3e-08 33.6 0.0 7.1e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG76747.1 - 0.016 14.4 0.1 0.063 12.4 0.0 1.8 2 0 0 2 2 2 0 Autophagy protein Apg17 Retrotrans_gag PF03732.17 GBG76747.1 - 0.057 13.7 0.3 0.61 10.4 0.0 2.6 2 1 0 2 2 2 0 Retrotransposon gag protein PK PF00224.21 GBG76749.1 - 2.1e-09 36.7 0.0 4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Sigma70_r2 PF04542.14 GBG76749.1 - 0.08 12.7 0.2 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 Sigma-70 region 2 Retrotrans_gag PF03732.17 GBG76749.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein PK PF00224.21 GBG76750.1 - 3e-63 213.8 1.4 3.9e-63 213.4 1.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG76750.1 - 1e-14 54.8 0.2 6.9e-14 52.1 0.0 2.3 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GBG76750.1 - 4.6e-05 22.7 0.0 9.6e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RibD_C PF01872.17 GBG76750.1 - 0.016 15.1 0.2 0.21 11.4 0.0 2.4 1 1 1 2 2 2 0 RibD C-terminal domain DUF659 PF04937.15 GBG76751.1 - 1.4e-13 51.0 0.0 2.8e-12 46.8 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG76753.1 - 3.8e-08 33.0 0.2 7.1e-08 32.1 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Vac14_Fig4_bd PF11916.8 GBG76755.1 - 6.1e-73 244.3 6.6 1.5e-72 243.0 6.6 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 GBG76755.1 - 1.1e-49 167.0 0.6 7.6e-40 135.4 0.0 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GBG76755.1 - 2.8e-14 52.0 7.6 0.00014 21.8 0.0 7.7 8 0 0 8 8 8 4 HEAT repeat Cnd1 PF12717.7 GBG76755.1 - 4.7e-12 46.2 1.3 1.7e-05 24.9 0.0 3.8 2 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GBG76755.1 - 9.4e-12 45.2 3.4 0.0015 19.0 0.0 6.3 6 0 0 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 GBG76755.1 - 1.5e-11 44.5 2.6 0.0071 16.7 0.0 5.5 3 2 3 6 6 6 4 HEAT repeats CLASP_N PF12348.8 GBG76755.1 - 8.6e-08 32.0 0.7 0.02 14.5 0.0 4.4 2 2 2 4 4 4 2 CLASP N terminal Tti2 PF10521.9 GBG76755.1 - 6.8e-06 25.8 0.1 0.1 12.1 0.0 4.5 3 1 1 5 5 5 1 Tti2 family RTP1_C1 PF10363.9 GBG76755.1 - 0.012 15.8 1.3 14 6.0 0.0 4.4 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 GBG76755.1 - 0.043 13.9 2.7 1.1 9.4 0.0 4.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat RVT_1 PF00078.27 GBG76756.1 - 3.5e-25 88.8 0.0 6.2e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76756.1 - 5.9e-21 74.7 0.1 1.5e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TPT PF03151.16 GBG76756.1 - 9.4e-18 64.6 5.3 1.4e-17 64.0 5.3 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family Integrase_H2C2 PF17921.1 GBG76756.1 - 1.1e-12 47.9 0.0 2.7e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG76756.1 - 2.9e-11 43.3 0.0 9.7e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase EamA PF00892.20 GBG76756.1 - 1.2e-07 32.0 18.6 1.1e-06 28.8 1.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GBG76756.1 - 0.0011 18.3 7.1 0.0019 17.5 7.1 1.3 1 0 0 1 1 1 1 UAA transporter family zf-H2C2 PF09337.10 GBG76756.1 - 0.02 15.1 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger PUNUT PF16913.5 GBG76756.1 - 2.2 7.4 10.9 23 4.1 10.9 2.1 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Ribosomal_S13_N PF08069.12 GBG76757.1 - 1.2e-31 108.5 0.3 2.3e-31 107.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 GBG76757.1 - 5.9e-15 55.2 0.7 8.4e-15 54.8 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 RT_RNaseH_2 PF17919.1 GBG76758.1 - 5e-30 103.5 0.0 7.2e-16 58.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76758.1 - 2.8e-20 72.6 0.0 6.7e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76758.1 - 1.4e-12 47.6 0.2 2.4e-12 46.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG76758.1 - 1.7e-12 47.1 0.0 2.9e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG76758.1 - 0.057 13.6 0.0 0.25 11.5 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain Methyltransf_11 PF08241.12 GBG76760.1 - 9e-18 64.7 0.0 1.7e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG76760.1 - 3.9e-17 62.7 0.0 8.1e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG76760.1 - 1.2e-15 57.5 0.0 1.2e-13 50.9 0.0 2.1 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GBG76760.1 - 4.4e-13 49.3 0.0 6.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG76760.1 - 2.4e-09 37.8 0.0 4.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG76760.1 - 3.9e-06 26.8 0.0 7.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 GBG76760.1 - 5.2e-06 25.9 0.0 8.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain GidB PF02527.15 GBG76760.1 - 0.00044 19.6 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G RrnaAD PF00398.20 GBG76760.1 - 0.00063 18.9 0.0 0.00084 18.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 GBG76760.1 - 0.0035 16.9 0.0 0.0073 15.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Met_10 PF02475.16 GBG76760.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.9 GBG76760.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF4535 PF15054.6 GBG76760.1 - 0.16 11.8 1.9 0.31 10.8 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) PCMT PF01135.19 GBG76760.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RVT_1 PF00078.27 GBG76761.1 - 1.4e-29 103.2 0.0 2.7e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CC2D2AN-C2 PF15625.6 GBG76761.1 - 9.2e-14 51.5 5.6 2.7e-13 50.0 0.0 3.3 3 0 0 3 3 3 1 CC2D2A N-terminal C2 domain gag-asp_proteas PF13975.6 GBG76761.1 - 1.2e-06 28.9 0.0 3.8e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76761.1 - 2.3e-06 28.2 0.0 6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76761.1 - 1.6e-05 24.7 0.0 3.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG76761.1 - 0.00025 20.8 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF2722 PF10846.8 GBG76761.1 - 0.00045 19.3 0.8 0.00045 19.3 0.8 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF2722) Retrotrans_gag PF03732.17 GBG76761.1 - 0.0049 17.1 0.3 0.0049 17.1 0.3 3.4 4 0 0 4 4 4 1 Retrotransposon gag protein EF-hand_14 PF17959.1 GBG76761.1 - 0.65 10.4 0.0 0.65 10.4 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain DUF659 PF04937.15 GBG76762.1 - 5.2e-36 123.8 0.1 1.2e-35 122.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG76762.1 - 0.039 14.0 0.9 0.039 14.0 0.9 2.0 2 0 0 2 2 2 0 BED zinc finger GHL6 PF14871.6 GBG76762.1 - 0.054 13.6 0.1 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 MFAP1 PF06991.11 GBG76762.1 - 3.6 7.4 15.8 4.3 7.1 2.7 2.5 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing HORMA PF02301.18 GBG76763.1 - 3.8e-23 82.2 0.0 7.4e-23 81.2 0.0 1.4 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 GBG76763.1 - 0.07 13.0 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial HORMA domain 2 Nop14 PF04147.12 GBG76765.1 - 0.061 11.5 1.9 0.061 11.5 1.9 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 GBG76765.1 - 0.38 9.9 1.2 0.51 9.5 1.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SATase_N PF06426.14 GBG76766.1 - 2.5e-39 133.9 0.3 4.1e-39 133.2 0.3 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 GBG76766.1 - 4.2e-13 48.4 10.1 2.4e-09 36.5 1.1 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GBG76766.1 - 1.3e-07 31.3 7.3 3.3e-06 26.7 2.5 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase JTB PF05439.12 GBG76767.1 - 0.0016 18.5 0.2 1.6 8.8 0.0 2.1 2 0 0 2 2 2 2 Jumping translocation breakpoint protein (JTB) INCENP_ARK-bind PF03941.15 GBG76768.1 - 1.3e-13 50.6 0.1 4.7e-13 48.9 0.1 2.1 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region RNA_pol_Rpc82 PF05645.13 GBG76769.1 - 0.63 9.8 9.4 1.3 8.7 9.4 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 EIIBC-GUT_N PF03612.14 GBG76769.1 - 1.5 8.5 4.0 3.2 7.5 4.0 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus NTP_transferase PF00483.23 GBG76771.1 - 0.052 13.1 0.1 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 Nucleotidyl transferase LPP PF04728.13 GBG76771.1 - 0.25 11.7 2.5 62 4.1 2.5 3.1 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DctP PF03480.13 GBG76772.1 - 3.9e-06 26.4 0.0 4.4e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein, family 7 FCD PF07729.12 GBG76772.1 - 2.7 8.4 6.1 15 6.0 3.3 2.3 1 1 1 2 2 2 0 FCD domain DctP PF03480.13 GBG76773.1 - 2.7e-13 49.9 0.0 3.5e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Myb_DNA-bind_4 PF13837.6 GBG76774.1 - 1.2e-08 35.2 2.0 2.8e-08 34.0 2.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG76774.1 - 0.019 15.3 1.9 0.023 15.0 0.6 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG76774.1 - 0.067 13.5 1.6 0.19 12.0 0.6 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG76774.1 - 0.11 12.6 0.3 0.28 11.3 0.3 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF5476 PF17570.2 GBG76774.1 - 0.36 11.2 1.2 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5476) DDE_Tnp_4 PF13359.6 GBG76775.1 - 1.1e-18 67.4 0.0 2.7e-18 66.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76775.1 - 1.4e-09 37.8 0.0 1.2e-07 31.6 0.0 2.2 1 1 1 2 2 2 2 Plant transposon protein RT_RNaseH PF17917.1 GBG76776.1 - 2.7e-22 79.0 0.0 5.1e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76776.1 - 1.3e-21 76.5 0.0 2.5e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76776.1 - 1.9e-19 69.5 1.2 4.7e-19 68.3 1.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG76776.1 - 1.4e-14 54.3 0.0 4.5e-14 52.6 0.0 1.9 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG76776.1 - 0.0041 17.3 0.2 0.0078 16.4 0.2 1.4 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG76778.1 - 7e-09 35.5 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MT PF12777.7 GBG76778.1 - 0.85 8.6 7.6 26 3.7 10.4 1.8 2 0 0 2 2 2 0 Microtubule-binding stalk of dynein motor ABC_tran PF00005.27 GBG76779.1 - 3.4e-20 73.0 0.0 4.9e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GBG76779.1 - 7.9e-11 41.8 4.9 1.1e-10 41.3 4.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_29 PF13555.6 GBG76779.1 - 0.0015 18.2 0.7 0.0031 17.2 0.7 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GBG76779.1 - 0.0018 18.2 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GBG76779.1 - 0.0025 18.0 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 GBG76779.1 - 0.0071 15.8 0.1 0.33 10.3 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GBG76779.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF2157 PF09925.9 GBG76779.1 - 0.034 13.9 3.2 0.048 13.5 1.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) AAA_16 PF13191.6 GBG76779.1 - 0.037 14.4 0.1 0.076 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 GBG76779.1 - 0.045 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GBG76779.1 - 0.053 14.0 0.1 0.079 13.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain Tmemb_55A PF09788.9 GBG76779.1 - 0.11 11.6 0.1 3.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 55A AAA_22 PF13401.6 GBG76779.1 - 0.21 11.9 0.2 0.53 10.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain FSA_C PF10479.9 GBG76780.1 - 0.16 10.1 0.2 0.21 9.7 0.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Jnk-SapK_ap_N PF09744.9 GBG76783.1 - 0.018 15.2 3.3 0.018 15.2 3.3 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FAM76 PF16046.5 GBG76783.1 - 0.31 10.4 2.2 0.49 9.7 2.2 1.2 1 0 0 1 1 1 0 FAM76 protein DUF3347 PF11827.8 GBG76783.1 - 0.97 9.6 4.2 1.8 8.7 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) TPR_MLP1_2 PF07926.12 GBG76783.1 - 2.2 8.4 15.3 0.21 11.7 5.7 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 GBG76783.1 - 3.9 6.7 10.4 0.066 12.6 1.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) RT_RNaseH PF17917.1 GBG76784.1 - 2e-21 76.3 0.0 1.7e-19 70.1 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76784.1 - 1.2e-18 67.0 0.0 9.2e-18 64.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC_4 PF14392.6 GBG76784.1 - 0.036 13.8 1.8 0.089 12.5 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG76785.1 - 1.2e-28 100.1 0.0 2e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76785.1 - 8.6e-18 64.2 0.0 1.1e-13 51.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76785.1 - 8.2e-15 54.7 1.2 1.6e-14 53.7 0.1 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG76785.1 - 6.6e-13 48.9 0.0 2.2e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG76785.1 - 4e-12 45.8 0.0 8.1e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG76785.1 - 5.4e-09 36.3 0.0 1.3e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG76785.1 - 5e-06 26.6 0.0 7.6e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger Glyco_hydro_47 PF01532.20 GBG76786.1 - 1.4e-115 386.9 0.0 1.9e-115 386.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Presenilin PF01080.17 GBG76786.1 - 2.8 6.6 5.4 7.6 5.2 5.4 1.7 1 0 0 1 1 1 0 Presenilin PKcGMP_CC PF16808.5 GBG76787.1 - 0.0041 16.9 0.7 0.0041 16.9 0.7 2.6 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF148 PF02520.17 GBG76787.1 - 1.6 8.9 4.7 7.9 6.6 4.8 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF148 Myb_DNA-bind_4 PF13837.6 GBG76788.1 - 0.00024 21.4 1.3 0.00047 20.5 1.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Gcn1_N PF12074.8 GBG76789.1 - 0.044 13.1 0.3 0.071 12.4 0.3 1.2 1 0 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal SecY PF00344.20 GBG76790.1 - 8.6e-96 320.8 4.6 1e-95 320.5 4.6 1.1 1 0 0 1 1 1 1 SecY translocase ATG101 PF07855.12 GBG76792.1 - 1.4e-42 145.3 0.1 1.7e-42 145.1 0.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 ATG101 PF07855.12 GBG76793.1 - 1.4e-42 145.3 0.1 1.6e-42 145.1 0.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 GIY-YIG PF01541.24 GBG76794.1 - 0.0078 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain RVT_1 PF00078.27 GBG76797.1 - 0.012 15.2 0.2 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PRP1_N PF06424.12 GBG76797.1 - 1.3 9.4 8.7 1.2 9.6 4.9 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Protocadherin PF08374.11 GBG76797.1 - 1.4 8.9 4.3 2.4 8.1 4.3 1.4 1 0 0 1 1 1 0 Protocadherin vATP-synt_E PF01991.18 GBG76797.1 - 1.8 7.9 17.9 2.6 7.4 17.9 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit zf-CCHC PF00098.23 GBG76798.1 - 6e-07 29.3 3.6 1.9e-06 27.6 3.6 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG76798.1 - 0.0058 16.4 0.8 0.014 15.2 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG76798.1 - 4.4 7.4 9.6 0.11 12.5 0.8 2.5 3 0 0 3 3 3 0 Zinc knuckle MoaC PF01967.21 GBG76799.1 - 2.5e-52 176.5 2.5 3.5e-52 176.1 2.5 1.2 1 0 0 1 1 1 1 MoaC family ZapB PF06005.12 GBG76800.1 - 0.002 18.5 0.0 0.002 18.5 0.0 3.8 2 2 0 2 2 2 1 Cell division protein ZapB FANCM-MHF_bd PF16783.5 GBG76800.1 - 0.13 12.3 4.4 0.45 10.6 4.4 1.9 1 0 0 1 1 1 0 FANCM to MHF binding domain DUF3090 PF11290.8 GBG76800.1 - 2.1 8.2 9.2 1.5 8.6 6.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) DUF1664 PF07889.12 GBG76800.1 - 2.2 8.3 6.2 0.47 10.5 0.2 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 GBG76800.1 - 4.2 7.9 8.4 8.6 6.9 2.3 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG76801.1 - 2.7e-25 89.2 0.0 3.9e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76801.1 - 4.8e-21 74.7 0.0 9.7e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76801.1 - 9.4e-12 45.2 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Response_reg PF00072.24 GBG76802.1 - 3.7e-19 68.9 0.1 2.1e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain RVT_1 PF00078.27 GBG76803.1 - 4.5e-31 108.1 0.1 8.1e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76803.1 - 0.0009 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG76803.1 - 0.016 15.8 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF5095 PF17016.5 GBG76803.1 - 0.21 11.3 0.2 0.42 10.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) HATPase_c PF02518.26 GBG76804.1 - 0.0025 18.3 0.0 0.2 12.2 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 GBG76806.1 - 1.5e-13 50.9 2.4 1.6e-13 50.9 0.0 2.3 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 GBG76806.1 - 1.7e-05 25.0 0.5 6.8e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 PAS domain CENP-Q PF13094.6 GBG76806.1 - 0.00085 19.6 0.7 0.00085 19.6 0.7 1.9 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Jnk-SapK_ap_N PF09744.9 GBG76806.1 - 0.012 15.8 10.0 0.012 15.8 10.0 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Herpes_UL6 PF01763.16 GBG76806.1 - 0.073 11.6 1.6 0.096 11.2 0.2 1.8 2 0 0 2 2 2 0 Herpesvirus UL6 like Atg14 PF10186.9 GBG76806.1 - 2.4 7.2 11.9 0.25 10.4 5.8 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 GBG76806.1 - 2.6 8.1 7.1 0.5 10.4 2.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Nup88 PF10168.9 GBG76806.1 - 3.1 5.5 4.1 5.3 4.7 4.1 1.2 1 0 0 1 1 1 0 Nuclear pore component Nup54 PF13874.6 GBG76806.1 - 3.5 7.7 11.4 3.3 7.8 7.5 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 BUD22 PF09073.10 GBG76807.1 - 0.095 12.0 14.3 0.12 11.7 14.3 1.0 1 0 0 1 1 1 0 BUD22 Merozoite_SPAM PF07133.11 GBG76807.1 - 0.51 10.3 22.5 0.79 9.7 22.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Cwf_Cwc_15 PF04889.12 GBG76807.1 - 1.2 8.9 12.3 1.5 8.5 12.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG76807.1 - 2.5 6.2 13.8 3 6.0 13.8 1.1 1 0 0 1 1 1 0 Nop14-like family MSA-2c PF12238.8 GBG76807.1 - 7.2 6.6 7.7 11 6.0 7.7 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c COPI_C PF06957.11 GBG76807.1 - 7.3 5.2 10.4 9.6 4.8 10.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CDC45 PF02724.14 GBG76807.1 - 8.2 4.6 11.8 10 4.3 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG76808.1 - 7.6e-28 96.5 0.0 3.2e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76808.1 - 1.4e-20 73.5 0.0 4.3e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76808.1 - 2.3e-11 43.7 0.5 1.2e-08 34.7 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76809.1 - 1.2e-19 70.5 0.0 2.3e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76809.1 - 1.6e-14 53.7 0.4 4.4e-14 52.3 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG76809.1 - 7.5e-12 45.0 0.0 1.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG76809.1 - 6.3e-11 42.5 0.0 2.2e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG76809.1 - 1.5e-09 37.8 0.0 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG76809.1 - 0.00087 19.5 0.1 0.0018 18.5 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG76810.1 - 5.3e-25 88.2 0.1 8.7e-25 87.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArfGap PF01412.18 GBG76811.1 - 1.6e-44 150.7 0.0 2.4e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-CCHC_6 PF15288.6 GBG76812.1 - 0.022 14.6 0.2 0.063 13.1 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle CLIP1_ZNF PF16641.5 GBG76812.1 - 0.023 14.6 0.5 0.042 13.7 0.5 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle MAGE PF01454.19 GBG76813.1 - 1.1e-30 107.0 0.7 2.9e-30 105.6 0.0 1.8 2 0 0 2 2 2 1 MAGE family CLP_protease PF00574.23 GBG76814.1 - 5.8e-60 202.3 0.0 8.9e-60 201.7 0.0 1.2 1 0 0 1 1 1 1 Clp protease CDK2AP PF09806.9 GBG76814.1 - 6.8 6.7 10.9 6.4 6.8 2.6 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Myb_DNA-bind_4 PF13837.6 GBG76815.1 - 0.00012 22.4 1.4 0.00024 21.4 1.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TetR_C_24 PF17932.1 GBG76815.1 - 0.25 11.6 0.0 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Peptidase_S24 PF00717.23 GBG76816.1 - 2.1e-06 27.6 0.1 4e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 GBG76816.1 - 0.0098 15.7 0.0 0.095 12.5 0.0 2.2 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 BAH PF01426.18 GBG76816.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 BAH domain HSP70 PF00012.20 GBG76817.1 - 4.4e-149 497.5 0.0 5.3e-149 497.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG76817.1 - 7.9e-13 47.9 0.0 3.8e-12 45.7 0.0 1.9 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG76817.1 - 0.0018 18.0 0.1 0.0047 16.7 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Actin PF00022.19 GBG76817.1 - 0.0067 15.1 0.0 1.2 7.6 0.0 2.5 3 0 0 3 3 3 2 Actin Hydantoinase_A PF01968.18 GBG76817.1 - 0.06 12.6 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Bromo_TP PF07524.13 GBG76818.1 - 4.3e-17 61.9 0.0 7e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 GBG76818.1 - 7.4e-16 58.4 0.1 7.4e-16 58.4 0.1 2.9 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term TFIID-31kDa PF02291.15 GBG76818.1 - 0.044 13.9 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit z-alpha PF02295.17 GBG76818.1 - 0.11 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain BRE PF06113.12 GBG76819.1 - 5.4e-28 97.8 0.3 1.3e-27 96.5 0.3 1.5 1 1 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) RWD PF05773.22 GBG76819.1 - 0.016 15.5 0.1 0.3 11.4 0.1 2.6 2 1 0 2 2 2 0 RWD domain RVT_1 PF00078.27 GBG76820.1 - 5.1e-27 94.8 0.0 6.8e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76820.1 - 2e-15 56.7 0.0 5.6e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76820.1 - 2.4e-07 31.0 0.0 5.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG76820.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 ATP-synt_C PF00137.21 GBG76821.1 - 8.7e-34 115.7 35.8 3.1e-20 72.3 13.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Man-6-P_recep PF02157.15 GBG76821.1 - 0.21 10.6 1.0 1.9 7.5 0.4 2.2 1 1 2 3 3 3 0 Mannose-6-phosphate receptor SecE PF00584.20 GBG76821.1 - 0.56 10.2 0.1 0.56 10.2 0.1 2.2 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Glycophorin_A PF01102.18 GBG76821.1 - 7.2 6.9 5.1 1 9.6 1.0 1.7 2 0 0 2 2 2 0 Glycophorin A CCDC53 PF10152.9 GBG76823.1 - 0.011 16.2 2.6 0.012 16.0 0.6 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex GRP PF07172.11 GBG76823.1 - 4.9 7.9 16.7 12 6.7 6.6 2.9 1 1 1 2 2 2 0 Glycine rich protein family CLIP1_ZNF PF16641.5 GBG76824.1 - 0.17 11.8 3.3 0.09 12.7 0.5 2.0 2 0 0 2 2 2 0 CLIP1 zinc knuckle Beta_helix PF13229.6 GBG76827.1 - 9.3e-11 41.8 2.9 2e-10 40.7 2.9 1.5 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG76827.1 - 5.1e-07 29.2 0.1 9.7e-07 28.3 0.1 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 GBG76827.1 - 0.008 15.5 0.4 0.017 14.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1565) RT_RNaseH_2 PF17919.1 GBG76828.1 - 6.3e-23 80.7 0.0 2.2e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76828.1 - 7.1e-12 45.6 0.0 2.4e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76828.1 - 4.5e-10 39.4 0.0 8.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pet191_N PF10203.9 GBG76829.1 - 3.8e-23 81.6 3.9 4.1e-23 81.4 3.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 GBG76829.1 - 0.049 13.3 1.3 0.053 13.2 0.2 1.5 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MYCBPAP PF14646.6 GBG76830.1 - 8.8e-52 176.5 0.1 8.8e-52 176.5 0.1 3.4 3 0 0 3 3 3 2 MYCBP-associated protein family RVT_1 PF00078.27 GBG76831.1 - 1.2e-29 103.5 0.1 1.9e-29 102.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76831.1 - 4.9e-24 84.3 0.0 1.5e-23 82.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76831.1 - 2.1e-23 82.6 0.0 5.7e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76831.1 - 9.5e-17 60.9 0.7 2.1e-16 59.8 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG76831.1 - 1.5e-06 28.6 0.0 4.9e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76831.1 - 5.5e-06 26.9 0.0 1.4e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76831.1 - 1.7e-05 24.6 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG76831.1 - 6.3e-05 22.8 0.0 0.00042 20.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG76831.1 - 0.00076 19.7 0.2 0.067 13.5 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_6 PF15288.6 GBG76831.1 - 0.12 12.2 0.1 0.51 10.2 0.1 2.1 1 0 0 1 1 1 0 Zinc knuckle DUF1682 PF07946.14 GBG76831.1 - 1.5 8.0 7.1 2.8 7.1 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Glyco_hydro_31 PF01055.26 GBG76832.1 - 2.6e-146 488.3 0.4 3.5e-146 487.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GBG76832.1 - 8.3e-22 77.3 0.0 5.9e-20 71.4 0.0 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 GBG76832.1 - 1.3e-05 25.3 0.0 3.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) T4BSS_DotI_IcmL PF11393.8 GBG76832.1 - 0.053 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component Galactosyl_T PF01762.21 GBG76833.1 - 3.3e-43 147.8 0.7 4.2e-43 147.4 0.7 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 GBG76833.1 - 0.0092 15.4 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Fringe-like CbtB PF09489.10 GBG76833.1 - 0.065 13.3 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) PBP-Tp47_c PF14888.6 GBG76833.1 - 0.081 12.9 0.3 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain C rve PF00665.26 GBG76834.1 - 3e-07 30.6 0.0 6.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1772 PF08592.11 GBG76835.1 - 3.4e-18 66.3 2.6 4.9e-18 65.8 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) UbiA PF01040.18 GBG76835.1 - 0.03 13.6 0.2 0.03 13.6 0.2 1.5 2 0 0 2 2 2 0 UbiA prenyltransferase family DUF4363 PF14276.6 GBG76835.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Prothymosin PF03247.14 GBG76836.1 - 1.9 9.0 28.9 0.3 11.6 8.8 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family Exo_endo_phos PF03372.23 GBG76837.1 - 7.8e-23 81.2 0.0 4.2e-16 59.2 0.0 3.3 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Torus PF16131.5 GBG76837.1 - 0.093 13.4 0.2 0.25 12.1 0.2 1.7 1 0 0 1 1 1 0 Torus domain Glucodextran_C PF09985.9 GBG76837.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal binding-module, SLH-like, of glucodextranase TFIIE-A_C PF11521.8 GBG76837.1 - 0.61 10.4 8.3 1.4 9.3 0.0 3.9 4 0 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha DEAD PF00270.29 GBG76838.1 - 4.6e-44 150.3 0.1 6.5e-44 149.8 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG76838.1 - 1.2e-26 93.2 0.9 2.2e-26 92.4 0.3 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG76838.1 - 0.00022 21.3 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG76838.1 - 0.0014 18.0 0.1 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DS PF01916.17 GBG76838.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase TFIIA PF03153.13 GBG76838.1 - 0.19 11.7 16.2 0.26 11.2 16.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DEAD PF00270.29 GBG76839.1 - 4.6e-44 150.3 0.1 6.5e-44 149.8 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG76839.1 - 1.2e-26 93.2 0.9 2.2e-26 92.4 0.3 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG76839.1 - 0.00022 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG76839.1 - 0.0014 18.0 0.1 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DS PF01916.17 GBG76839.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase TFIIA PF03153.13 GBG76839.1 - 0.18 11.8 15.7 0.24 11.3 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Transket_pyr PF02779.24 GBG76842.1 - 3.4e-46 157.2 0.0 4.6e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GBG76842.1 - 1.2e-42 144.7 0.0 2.4e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 GBG76842.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Transket_pyr PF02779.24 GBG76843.1 - 2.7e-47 160.8 0.0 3.7e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GBG76843.1 - 1.3e-42 144.6 0.0 2.8e-42 143.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 GBG76843.1 - 0.0016 18.7 0.0 0.0043 17.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Peptidase_M20 PF01546.28 GBG76843.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 RVT_1 PF00078.27 GBG76844.1 - 1.3e-27 96.8 0.1 5.4e-27 94.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76844.1 - 1.2e-22 79.8 0.0 4.4e-22 78.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76844.1 - 1.4e-21 76.7 0.0 7.5e-21 74.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76844.1 - 2.1e-09 37.6 0.0 6.1e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG76844.1 - 4.9e-07 30.3 0.0 1.2e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76844.1 - 8.9e-07 28.8 0.0 6.6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG76844.1 - 2.8e-06 27.4 1.8 6.6e-06 26.1 1.8 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG76844.1 - 0.00026 21.5 0.0 0.00072 20.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG76844.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG76844.1 - 0.077 13.3 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein AMP-binding_C_2 PF14535.6 GBG76844.1 - 0.16 12.3 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Brucella_OMP2 PF05244.11 GBG76844.1 - 0.27 10.6 0.6 0.81 9.0 0.1 1.9 2 0 0 2 2 2 0 Brucella outer membrane protein 2 zf-NF-X1 PF01422.17 GBG76848.1 - 5.9e-15 55.0 143.8 2.5e-07 30.6 14.5 9.2 8 0 0 8 8 8 4 NF-X1 type zinc finger Dscam_C PF12355.8 GBG76849.1 - 0.032 15.2 2.8 0.067 14.2 2.8 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal V-SNARE_C PF12352.8 GBG76849.1 - 0.039 14.3 1.2 4.9 7.5 0.3 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Exo_endo_phos PF03372.23 GBG76850.1 - 6.5e-13 48.7 0.0 1.8e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG76850.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Mon2_C PF16206.5 GBG76852.1 - 2.7e-53 181.3 0.2 4.8e-43 147.4 0.2 4.3 3 1 1 4 4 4 3 C-terminal region of Mon2 protein DCB PF16213.5 GBG76852.1 - 6.6e-36 123.6 4.6 1.8e-35 122.2 4.6 1.8 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 GBG76852.1 - 1.4e-30 106.3 0.1 1.4e-30 106.3 0.1 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 GBG76852.1 - 5.9e-06 26.1 0.6 0.019 15.2 0.2 4.4 3 0 0 3 3 3 1 HEAT repeat DUF3384 PF11864.8 GBG76852.1 - 0.0016 17.4 0.2 0.0016 17.4 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) HEAT_EZ PF13513.6 GBG76852.1 - 0.0027 18.2 0.0 9.3 6.9 0.0 4.3 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 GBG76852.1 - 0.023 15.1 0.2 2.5 8.5 0.1 3.6 3 0 0 3 3 3 0 HEAT repeats DUF1981 PF09324.10 GBG76852.1 - 0.04 13.8 0.0 0.55 10.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Fanconi_A PF03511.14 GBG76852.1 - 0.1 12.5 0.0 15 5.6 0.1 2.8 2 0 0 2 2 2 0 Fanconi anaemia group A protein PAE PF03283.13 GBG76853.1 - 3.1e-120 401.5 0.0 3.8e-120 401.3 0.0 1.0 1 0 0 1 1 1 1 Pectinacetylesterase NAD_binding_10 PF13460.6 GBG76854.1 - 5.2e-31 108.0 0.0 1.1e-16 61.3 0.0 2.3 2 0 0 2 2 2 2 NAD(P)H-binding CIA30 PF08547.12 GBG76854.1 - 1.7e-21 76.9 0.0 2.6e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NmrA PF05368.13 GBG76854.1 - 1.1e-06 28.4 0.0 6.4e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 GBG76854.1 - 5.2e-06 26.1 0.0 2.2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GBG76854.1 - 2e-05 23.9 0.0 2.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 GBG76854.1 - 0.00028 21.1 0.0 0.0007 19.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 GBG76854.1 - 0.0022 17.0 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 GBG76854.1 - 0.0033 17.4 0.1 0.0056 16.6 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GBG76854.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 GBG76854.1 - 0.014 14.8 0.1 0.038 13.4 0.1 1.6 2 0 0 2 2 2 0 short chain dehydrogenase SGBP_B_XBD PF18329.1 GBG76854.1 - 0.027 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain DapB_N PF01113.20 GBG76854.1 - 0.046 13.8 0.3 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 GBG76854.1 - 0.05 12.8 0.1 0.25 10.5 0.1 1.9 2 0 0 2 2 2 0 Male sterility protein WD40 PF00400.32 GBG76855.1 - 2.1e-23 82.2 9.3 3.1e-06 27.8 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GBG76855.1 - 1e-14 54.3 2.6 0.00011 21.3 0.1 4.1 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 GBG76855.1 - 3.3e-12 46.5 0.5 0.039 14.3 0.0 5.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GBG76855.1 - 0.04 12.7 0.0 0.43 9.3 0.0 2.3 2 1 0 2 2 2 0 Nup133 N terminal like ODV-E18 PF10717.9 GBG76855.1 - 0.048 13.5 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Ricin_B_lectin PF00652.22 GBG76855.1 - 0.058 13.6 1.4 0.15 12.3 1.0 1.9 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Nbas_N PF15492.6 GBG76855.1 - 0.063 12.6 0.0 0.52 9.6 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RT_RNaseH_2 PF17919.1 GBG76856.1 - 4.3e-36 123.0 0.1 7.1e-36 122.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76856.1 - 8e-32 109.7 0.1 1.4e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76856.1 - 1.3e-09 37.9 0.2 2.1e-09 37.2 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L28 PF00830.19 GBG76857.1 - 1.2e-21 76.6 4.9 1.4e-21 76.4 4.9 1.1 1 0 0 1 1 1 1 Ribosomal L28 family Asp_protease_2 PF13650.6 GBG76858.1 - 0.022 15.4 0.0 0.05 14.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG76858.1 - 0.062 13.0 0.3 0.062 13.0 0.3 2.2 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like p450 PF00067.22 GBG76859.1 - 2.3e-74 250.8 0.0 4.1e-53 180.8 0.0 2.4 2 0 0 2 2 2 2 Cytochrome P450 Asp_protease_2 PF13650.6 GBG76859.1 - 1.4e-07 32.0 0.0 3.3e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76859.1 - 1.6e-07 31.8 0.0 4.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG76859.1 - 1.6e-05 24.6 0.0 4.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG76859.1 - 0.034 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 GBG76860.1 - 3.8e-06 27.1 0.0 5.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG76860.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Presenilin PF01080.17 GBG76860.1 - 0.82 8.4 2.7 1 8.0 2.7 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG76860.1 - 1 7.5 19.6 1.2 7.2 19.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG76860.1 - 4.5 6.6 20.1 5.7 6.3 20.1 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG76860.1 - 5.1 5.3 13.5 6 5.0 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TrkH PF02386.16 GBG76861.1 - 2.2e-53 181.5 18.8 2.3e-51 174.8 14.3 3.3 2 1 0 2 2 2 2 Cation transport protein DUF4632 PF15451.6 GBG76861.1 - 0.08 13.0 4.7 0.095 12.8 0.9 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) DLIC PF05783.11 GBG76861.1 - 1.7 7.4 5.0 3.5 6.4 5.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) GCP_C_terminal PF04130.13 GBG76862.1 - 3.3e-25 89.2 0.7 6.6e-25 88.2 0.7 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GBG76862.1 - 2.1e-15 57.2 0.0 4.6e-14 52.8 0.0 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal Mating_C PF12737.7 GBG76863.1 - 0.0013 18.1 1.6 0.0013 18.1 1.6 1.9 2 0 0 2 2 2 1 C-terminal domain of homeodomain 1 Fucose_iso_N2 PF07882.12 GBG76863.1 - 1.6 8.2 6.0 3 7.4 6.0 1.4 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain DUF728 PF05304.12 GBG76863.1 - 5.9 6.7 10.0 4 7.3 4.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF728) gag-asp_proteas PF13975.6 GBG76864.1 - 1.6e-05 25.3 0.1 4.5e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76864.1 - 0.00024 21.7 0.1 0.0007 20.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG76864.1 - 0.00063 19.5 0.1 0.001 18.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76864.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG76864.1 - 0.046 13.8 1.9 0.089 12.9 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle cNMP_binding PF00027.29 GBG76864.1 - 0.086 12.9 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain Topo_Zn_Ribbon PF08272.11 GBG76864.1 - 0.13 11.9 0.2 0.26 11.0 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RRM_1 PF00076.22 GBG76865.1 - 6.8e-29 99.5 0.1 2.1e-23 81.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Radical_SAM_N PF08497.10 GBG76865.1 - 0.22 10.7 8.0 0.43 9.8 8.0 1.5 1 0 0 1 1 1 0 Radical SAM N-terminal RRM_7 PF16367.5 GBG76865.1 - 0.3 11.3 0.0 0.3 11.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif GREB1 PF15782.5 GBG76865.1 - 0.41 7.7 15.4 0.55 7.3 15.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FapA PF03961.13 GBG76865.1 - 0.44 9.1 7.1 0.78 8.3 7.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Serinc PF03348.15 GBG76865.1 - 1.1 8.1 4.5 1.8 7.4 4.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) ALMT PF11744.8 GBG76865.1 - 1.2 7.9 12.7 2.2 7.0 12.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Connexin PF00029.19 GBG76865.1 - 1.6 8.5 10.0 3.7 7.2 10.0 1.6 1 0 0 1 1 1 0 Connexin LMBR1 PF04791.16 GBG76865.1 - 2.4 7.0 6.5 3.3 6.5 6.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Membralin PF09746.9 GBG76865.1 - 2.5 7.0 12.5 4.7 6.1 12.5 1.4 1 0 0 1 1 1 0 Tumour-associated protein CLN3 PF02487.17 GBG76865.1 - 8.2 5.3 10.0 16 4.4 10.0 1.4 1 0 0 1 1 1 0 CLN3 protein Band_3_cyto PF07565.13 GBG76865.1 - 8.7 6.1 20.5 0.27 11.0 13.6 1.9 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Glycos_transf_2 PF00535.26 GBG76868.1 - 9.6e-13 48.3 0.1 2.6e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 GBG76868.1 - 0.035 14.6 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 2 Retrotrans_gag PF03732.17 GBG76869.1 - 0.00012 22.2 1.2 0.00093 19.4 0.1 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Lipin_mid PF16876.5 GBG76869.1 - 0.042 14.0 0.8 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Glyco_trans_2_3 PF13632.6 GBG76870.1 - 2.8e-13 50.2 0.8 7e-13 48.9 0.8 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GBG76870.1 - 0.00029 20.8 0.1 0.00056 19.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 GBG76870.1 - 0.00095 17.8 0.3 0.0018 16.9 0.3 1.3 1 0 0 1 1 1 1 Cellulose synthase UPF0270 PF06794.12 GBG76870.1 - 0.076 13.1 0.1 57 3.9 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) GTP_EFTU PF00009.27 GBG76871.1 - 2.1e-59 200.4 0.1 2.7e-59 200.0 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GBG76871.1 - 5e-29 100.9 0.0 9.6e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GBG76871.1 - 3.3e-17 62.6 4.0 7.3e-17 61.5 4.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG76871.1 - 5.5e-05 23.2 0.0 9.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 GBG76871.1 - 0.03 13.9 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_S8 PF00410.19 GBG76871.1 - 0.043 13.8 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S8 PduV-EutP PF10662.9 GBG76871.1 - 0.098 12.4 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DDE_Tnp_4 PF13359.6 GBG76872.1 - 7.7e-22 77.6 0.0 1.1e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG76872.1 - 1.4e-13 51.0 0.0 3.1e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG76872.1 - 0.085 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Peptidase_M24 PF00557.24 GBG76873.1 - 1.2e-25 90.4 0.0 2e-18 66.8 0.0 2.0 1 1 1 2 2 2 2 Metallopeptidase family M24 Integrase_H2C2 PF17921.1 GBG76874.1 - 1.6e-07 31.3 0.0 3.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76874.1 - 2.5e-06 27.2 0.0 4.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76874.1 - 0.00027 21.1 0.1 0.0019 18.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG76874.1 - 0.00056 20.1 0.1 0.0012 19.0 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG76874.1 - 0.0016 18.5 0.1 0.0044 17.0 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3043 PF11241.8 GBG76874.1 - 0.036 14.1 0.1 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) TIM PF00121.18 GBG76876.1 - 3.7e-75 252.4 0.3 4.1e-75 252.3 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase RT_RNaseH_2 PF17919.1 GBG76877.1 - 1.5e-30 105.2 0.0 3e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76877.1 - 1.4e-23 83.1 0.1 2.9e-23 82.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76877.1 - 9.8e-16 58.0 0.1 2e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG76877.1 - 5.5e-15 55.2 0.1 1.4e-14 53.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG76877.1 - 0.0074 16.0 0.6 0.065 12.9 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) Clr5 PF14420.6 GBG76877.1 - 0.09 13.0 0.6 3.6 7.9 0.5 3.0 2 0 0 2 2 2 0 Clr5 domain Cation_efflux PF01545.21 GBG76878.1 - 3.1e-33 115.2 16.2 3.8e-33 114.9 16.2 1.1 1 0 0 1 1 1 1 Cation efflux family DUF805 PF05656.14 GBG76878.1 - 0.65 10.4 4.7 2.5 8.5 4.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF805) TPT PF03151.16 GBG76879.1 - 8e-17 61.5 26.9 1e-16 61.1 26.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family COX14 PF14880.6 GBG76879.1 - 0.12 12.2 0.2 0.46 10.4 0.2 2.0 1 0 0 1 1 1 0 Cytochrome oxidase c assembly CCDC53 PF10152.9 GBG76879.1 - 0.94 9.9 3.8 8.9 6.7 0.6 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3558 PF12079.8 GBG76879.1 - 1.4 8.9 5.1 2.4 8.1 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Mito_fiss_reg PF05308.11 GBG76879.1 - 1.9 8.5 11.4 4.8 7.2 11.4 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3951 PF13131.6 GBG76879.1 - 2.2 8.6 9.8 0.85 9.9 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) CAP_N PF01213.19 GBG76879.1 - 2.8 7.4 16.1 5.2 6.5 16.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EamA PF00892.20 GBG76879.1 - 3.9 7.6 37.3 3.8 7.7 13.4 2.9 1 1 0 2 2 2 0 EamA-like transporter family RVT_1 PF00078.27 GBG76880.1 - 2e-26 92.9 0.0 3e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG76880.1 - 2.1e-09 37.2 0.0 3.9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF659 PF04937.15 GBG76882.1 - 3.4e-23 82.2 0.0 6.6e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG76884.1 - 8.1e-31 106.0 0.0 1.9e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76884.1 - 1.1e-29 103.5 0.0 2.2e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76884.1 - 3.4e-25 88.4 0.0 8.8e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Neisseria_TspB PF05616.13 GBG76884.1 - 0.33 9.4 6.9 0.54 8.7 6.9 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein EndIII_4Fe-2S PF10576.9 GBG76884.1 - 9.1 6.8 6.6 20 5.6 6.6 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III RVT_1 PF00078.27 GBG76885.1 - 5.3e-30 104.6 0.0 1e-29 103.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM60A PF15396.6 GBG76885.1 - 5.4 7.0 8.5 20 5.1 8.5 1.9 1 0 0 1 1 1 0 Protein Family FAM60A PurK_C PF17769.1 GBG76886.1 - 0.16 11.7 0.1 0.34 10.6 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain NOA36 PF06524.12 GBG76887.1 - 0.11 11.8 10.1 0.12 11.6 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein PGA2 PF07543.12 GBG76887.1 - 0.94 9.5 15.6 1.6 8.7 15.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2201_N PF13203.6 GBG76887.1 - 0.95 9.0 11.8 1.4 8.5 11.8 1.4 1 1 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.12 GBG76887.1 - 3.4 7.4 7.7 3.3 7.4 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 GBG76887.1 - 3.8 7.1 9.2 7.3 6.2 9.2 1.6 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 GBG76887.1 - 5.7 4.9 13.7 6.5 4.7 13.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop53 PF07767.11 GBG76887.1 - 6.2 6.1 17.0 9 5.6 17.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GBG76887.1 - 7.2 4.7 15.8 7.4 4.7 15.8 1.0 1 0 0 1 1 1 0 Nop14-like family gag-asp_proteas PF13975.6 GBG76888.1 - 1.2e-07 32.2 0.0 2.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76888.1 - 8.2e-07 29.6 0.0 1.8e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG76888.1 - 0.002 18.0 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG76888.1 - 0.0022 17.8 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG76888.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease MbeD_MobD PF04899.12 GBG76888.1 - 1.2 9.3 3.8 20 5.4 1.6 2.5 2 0 0 2 2 2 0 MbeD/MobD like CRM1_C PF08767.11 GBG76890.1 - 4.7e-123 410.4 14.7 2.4e-122 408.1 5.9 3.2 3 0 0 3 3 3 2 CRM1 C terminal Xpo1 PF08389.12 GBG76890.1 - 2.2e-39 134.9 2.4 2.2e-39 134.9 2.4 5.1 5 2 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 GBG76890.1 - 1.1e-29 101.9 2.3 2.8e-29 100.5 2.3 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 GBG76890.1 - 3.5e-29 100.6 1.1 3.5e-29 100.6 1.1 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 GBG76890.1 - 1.5e-17 63.3 0.6 1.2e-16 60.3 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 GBG76890.1 - 1.5e-16 59.6 1.9 3.7e-16 58.3 1.9 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat Sec7_N PF12783.7 GBG76890.1 - 1.7e-05 24.8 18.6 0.0082 16.1 0.2 5.0 4 2 1 5 5 5 3 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3385 PF11865.8 GBG76890.1 - 0.078 12.9 4.7 0.32 10.9 0.0 4.0 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 GBG76890.1 - 0.095 13.3 2.3 3.5 8.3 0.1 3.4 3 0 0 3 3 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 GBG76890.1 - 0.23 10.0 5.6 0.038 12.6 0.2 2.5 4 0 0 4 4 4 0 Adaptin N terminal region RIX1 PF08167.12 GBG76890.1 - 1.2 8.8 9.8 2.1 8.1 0.0 4.3 4 1 0 5 5 5 0 rRNA processing/ribosome biogenesis START PF01852.19 GBG76891.1 - 0.91 8.9 6.0 1 8.7 6.0 1.1 1 0 0 1 1 1 0 START domain BUD22 PF09073.10 GBG76891.1 - 4.9 6.4 21.1 6 6.1 21.1 1.0 1 0 0 1 1 1 0 BUD22 Glyco_transf_64 PF09258.10 GBG76892.1 - 2.2e-65 220.4 0.0 3.8e-65 219.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 GBG76892.1 - 7.8e-05 22.4 7.9 0.014 15.0 7.9 3.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GBG76892.1 - 0.0085 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative CdiI_N PF18228.1 GBG76892.1 - 0.017 14.9 0.0 4.7 7.1 0.0 2.8 2 0 0 2 2 2 0 CdiI N-terminal domain Nucleotid_trans PF03407.16 GBG76892.1 - 0.022 14.7 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_hydro_2 PF00703.21 GBG76893.1 - 4.6e-09 36.9 0.0 8.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_GlcNase PF18368.1 GBG76893.1 - 1.6e-08 34.6 0.2 1.1e-07 31.9 0.0 2.5 3 0 0 3 3 3 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2_C PF02836.17 GBG76893.1 - 0.001 18.2 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 GBG76893.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Histone PF00125.24 GBG76894.1 - 1.8e-15 57.5 0.0 1.8e-15 57.5 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG76894.1 - 0.028 14.8 0.1 0.063 13.7 0.1 1.6 1 0 0 1 1 1 0 CENP-S protein RT_RNaseH PF17917.1 GBG76895.1 - 1.1e-22 80.3 0.0 2.8e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76895.1 - 1.6e-21 76.2 0.0 3.3e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76895.1 - 5.7e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG76895.1 - 0.018 15.6 0.1 0.071 13.7 0.1 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76895.1 - 0.018 15.6 0.0 0.056 14.1 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Presenilin PF01080.17 GBG76895.1 - 1.3 7.7 4.3 3.6 6.3 4.3 1.7 1 0 0 1 1 1 0 Presenilin ArfGap PF01412.18 GBG76896.1 - 5.5e-33 113.5 0.0 2e-31 108.5 0.0 2.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 GBG76896.1 - 2.6e-31 109.1 5.5 6.6e-19 68.5 5.8 2.3 1 1 1 2 2 2 2 BAR domain of APPL family Ank_2 PF12796.7 GBG76896.1 - 4.5e-19 68.8 1.6 6.1e-10 39.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 GBG76896.1 - 5.9e-16 58.9 0.1 1e-15 58.1 0.1 1.4 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 GBG76896.1 - 1.8e-10 41.1 0.4 1.1e-06 29.0 0.5 3.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG76896.1 - 4.1e-09 36.5 0.5 2.5e-06 27.7 0.2 2.7 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG76896.1 - 6.6e-09 35.3 0.8 0.01 16.3 0.2 4.0 4 0 0 4 4 3 2 Ankyrin repeat Ank PF00023.30 GBG76896.1 - 1.7e-08 34.5 3.5 0.029 14.8 0.2 3.7 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 GBG76896.1 - 1.7e-06 28.2 0.1 5.8e-06 26.5 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GBG76896.1 - 0.0002 21.7 0.2 0.00061 20.2 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GBG76896.1 - 0.0052 16.9 0.3 0.025 14.7 0.3 2.0 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 GBG76896.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain DUF883 PF05957.13 GBG76896.1 - 2.4 8.8 5.9 2.1 9.0 0.2 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) bZIP_2 PF07716.15 GBG76896.1 - 9.1 6.5 9.3 2.4 8.3 3.7 2.4 2 0 0 2 2 2 0 Basic region leucine zipper zf_C2H2_10 PF18414.1 GBG76897.1 - 0.12 12.0 0.9 0.2 11.2 0.9 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger Chlam_PMP PF02415.17 GBG76898.1 - 9.1e-08 32.1 13.0 0.018 15.5 0.1 5.8 7 0 0 7 7 7 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 GBG76898.1 - 3.7e-05 23.6 4.1 0.00014 21.7 3.7 2.1 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG76898.1 - 0.034 13.4 0.4 0.05 12.9 0.4 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Rrp15p PF07890.12 GBG76899.1 - 1.8e-19 70.4 2.2 4.8e-19 69.0 2.2 1.8 1 0 0 1 1 1 1 Rrp15p CDC45 PF02724.14 GBG76899.1 - 0.44 8.8 7.4 0.76 8.0 7.4 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_14 PF13428.6 GBG76900.1 - 0.036 14.9 1.1 5.5 8.1 0.3 3.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF596 PF04591.12 GBG76900.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 TPR_7 PF13176.6 GBG76900.1 - 0.092 12.8 1.5 4.4 7.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG76900.1 - 0.2 12.3 4.2 0.81 10.4 0.3 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG76900.1 - 0.37 11.0 1.4 3.6 7.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG76901.1 - 9e-31 107.1 0.1 1.4e-30 106.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76901.1 - 4.9e-25 87.5 0.0 9.8e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76901.1 - 1.2e-23 83.4 0.0 2.3e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76901.1 - 1.4e-14 53.9 0.4 1.4e-14 53.9 0.4 3.0 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG76901.1 - 0.0023 17.8 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG76901.1 - 0.079 13.2 0.1 0.27 11.5 0.1 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Integrin_b_cyt PF08725.11 GBG76901.1 - 0.079 12.7 0.3 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain SLT PF01464.20 GBG76902.1 - 4.2e-14 52.2 0.0 7e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain DUF659 PF04937.15 GBG76903.1 - 3.9e-22 78.7 0.0 8.3e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Chromo PF00385.24 GBG76903.1 - 5.2e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG76903.1 - 3.3e-06 27.3 0.1 4.9e-05 23.5 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain CRS1_YhbY PF01985.21 GBG76904.1 - 0.03 14.5 0.1 0.046 13.9 0.1 1.4 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain PP2C PF00481.21 GBG76905.1 - 1.5e-36 126.4 1.6 8e-27 94.5 0.0 3.4 3 0 0 3 3 3 3 Protein phosphatase 2C SUIM_assoc PF16619.5 GBG76905.1 - 0.0045 17.0 6.4 0.026 14.6 6.4 2.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 PBP1_TM PF14812.6 GBG76906.1 - 0.26 11.7 3.5 0.49 10.8 3.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal rve PF00665.26 GBG76907.1 - 3.4e-08 33.7 0.0 9.1e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain ZapB PF06005.12 GBG76907.1 - 0.0056 17.1 2.1 0.011 16.1 0.1 2.5 2 0 0 2 2 2 1 Cell division protein ZapB RT_RNaseH_2 PF17919.1 GBG76908.1 - 2.2e-27 95.0 0.0 6.1e-27 93.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76908.1 - 1.9e-25 89.2 0.0 4.5e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76908.1 - 9.3e-18 64.1 0.2 3.8e-17 62.1 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG76908.1 - 3.2e-09 37.0 0.0 1e-08 35.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG76908.1 - 2.1e-05 24.7 5.4 0.0016 18.7 0.1 4.1 2 1 1 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG76908.1 - 0.0003 20.4 0.1 0.00055 19.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG76908.1 - 0.0042 17.0 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG76908.1 - 0.043 14.0 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger AIF-MLS PF14962.6 GBG76908.1 - 0.39 10.7 6.4 0.79 9.7 6.4 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Fib_alpha PF08702.10 GBG76908.1 - 0.4 10.9 6.6 0.78 9.9 0.4 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Proteasome PF00227.26 GBG76909.1 - 8e-56 188.5 0.1 9.4e-56 188.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit ERG4_ERG24 PF01222.17 GBG76910.1 - 2.1e-58 198.1 12.9 1.7e-41 142.4 1.0 2.7 2 1 1 3 3 3 2 Ergosterol biosynthesis ERG4/ERG24 family Dimer_Tnp_hAT PF05699.14 GBG76910.1 - 2.4e-08 33.6 0.2 6.1e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1295 PF06966.12 GBG76910.1 - 1.3e-07 31.4 0.0 2.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Retrotrans_gag PF03732.17 GBG76911.1 - 0.00038 20.7 0.9 0.13 12.5 0.0 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein Dynactin_p22 PF07426.11 GBG76911.1 - 0.042 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Dynactin subunit p22 ZapB PF06005.12 GBG76911.1 - 0.17 12.4 0.1 0.17 12.4 0.1 3.4 3 1 0 3 3 3 0 Cell division protein ZapB NBD_C PF17042.5 GBG76911.1 - 0.56 10.7 4.9 1.6 9.3 4.9 1.8 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain SAB PF04382.13 GBG76911.1 - 4.2 7.5 6.1 1.3 9.2 0.3 2.9 3 0 0 3 3 3 0 SAB domain ERG4_ERG24 PF01222.17 GBG76912.1 - 5.7e-06 25.3 0.0 5.8e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family BUD22 PF09073.10 GBG76913.1 - 0.35 10.2 24.4 0.4 10.0 24.4 1.1 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 GBG76913.1 - 4 6.3 3.8 5 6.0 3.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 GBG76913.1 - 5.4 6.1 4.6 5.6 6.1 4.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 GBG76913.1 - 6.4 4.8 32.0 9.4 4.3 32.0 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG76913.1 - 8.9 5.0 7.1 9.1 4.9 7.1 1.1 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG76914.1 - 2.1e-14 53.6 0.0 4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76914.1 - 0.00026 21.2 0.0 0.00073 19.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG76914.1 - 0.0076 16.9 0.0 0.019 15.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG76915.1 - 4.2e-29 101.6 0.1 6.9e-29 100.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG76915.1 - 3.9e-11 43.2 0.1 9.6e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG76915.1 - 8.3e-11 41.8 1.1 8.5e-10 38.6 0.0 3.2 4 0 0 4 4 4 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG76915.1 - 0.032 14.4 0.0 0.096 12.9 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG76916.1 - 1.8e-05 25.2 0.3 4.8e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76916.1 - 0.00055 20.5 0.5 0.0019 18.8 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG76916.1 - 0.0014 18.4 0.1 0.0023 17.7 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76916.1 - 0.0022 17.8 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG76916.1 - 0.021 14.5 0.4 0.048 13.3 0.4 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Molybdopterin_N PF18364.1 GBG76916.1 - 0.05 13.6 0.1 0.87 9.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain zf-CCHC PF00098.23 GBG76916.1 - 0.054 13.6 1.9 0.092 12.9 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG76918.1 - 5.5e-14 52.0 0.0 1.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76918.1 - 1e-11 45.0 0.0 3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76918.1 - 1.7e-07 31.4 0.0 4.8e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG76918.1 - 3.9e-06 26.5 0.0 1.2e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG76918.1 - 2.2e-05 24.9 0.0 5.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG76918.1 - 0.0015 18.8 0.0 0.0043 17.3 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG76918.1 - 0.0037 17.0 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG76918.1 - 0.011 16.4 0.1 0.051 14.2 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG76919.1 - 0.0043 17.3 0.6 0.018 15.3 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG76919.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Ras PF00071.22 GBG76919.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Ras family GAS PF13851.6 GBG76919.1 - 5.1 6.4 8.8 0.98 8.7 1.8 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding FLYWCH_u PF16662.5 GBG76920.1 - 0.0096 16.0 0.2 0.04 14.0 0.1 2.2 1 1 0 1 1 1 1 FLYWCH-type zinc finger-containing protein 1 RVT_1 PF00078.27 GBG76921.1 - 9.2e-09 35.1 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG76921.1 - 0.00013 22.5 0.1 0.00048 20.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Sporozoite_P67 PF05642.11 GBG76921.1 - 0.006 14.7 6.6 0.0067 14.6 5.3 1.7 1 1 0 1 1 1 1 Sporozoite P67 surface antigen Asp_protease_2 PF13650.6 GBG76921.1 - 0.011 16.4 0.0 0.037 14.7 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG76921.1 - 0.018 15.3 0.1 1.1 9.6 0.0 3.0 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG76921.1 - 0.24 11.6 13.0 0.035 14.2 1.5 3.7 3 0 0 3 3 3 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG76922.1 - 2.7e-32 110.8 0.1 7.3e-32 109.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG76922.1 - 1.4e-28 99.2 0.3 2.7e-28 98.3 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG76922.1 - 3.3e-18 65.5 0.4 1e-17 64.0 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG76922.1 - 1.8e-17 63.6 0.0 3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG76922.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger WASH_WAHD PF11945.8 GBG76923.1 - 2.6e-27 96.1 0.0 2.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex Pkinase_Tyr PF07714.17 GBG76924.1 - 2.3e-42 145.1 0.0 3.8e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76924.1 - 1.2e-41 142.9 0.0 1.6e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Malectin_like PF12819.7 GBG76924.1 - 2.8e-24 85.9 0.0 2.4e-21 76.3 0.0 2.6 2 1 0 2 2 2 2 Malectin-like domain Malectin PF11721.8 GBG76924.1 - 1.2e-15 58.0 0.0 6.3e-09 36.1 0.0 2.9 2 1 0 2 2 2 2 Malectin domain LRR_8 PF13855.6 GBG76924.1 - 0.00014 21.5 3.3 0.00031 20.4 3.3 1.6 1 0 0 1 1 1 1 Leucine rich repeat ABC1 PF03109.16 GBG76924.1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family LRRNT_2 PF08263.12 GBG76924.1 - 0.025 14.9 0.0 0.081 13.3 0.0 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 GBG76924.1 - 0.1 13.1 2.6 0.4 11.2 1.9 2.4 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) APH PF01636.23 GBG76924.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-bind_4 PF13837.6 GBG76927.1 - 8.8e-07 29.2 1.4 4.1e-06 27.1 2.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF4944 PF16302.5 GBG76928.1 - 0.27 11.3 9.5 5.1 7.2 0.5 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4944) Pkinase_Tyr PF07714.17 GBG76929.1 - 3.9e-42 144.3 0.0 6.8e-42 143.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76929.1 - 2.1e-41 142.1 0.0 2.9e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Malectin_like PF12819.7 GBG76929.1 - 7.4e-23 81.2 0.0 2.3e-20 73.1 0.0 2.4 1 1 0 2 2 2 2 Malectin-like domain Malectin PF11721.8 GBG76929.1 - 1.1e-17 64.6 0.0 2.1e-10 40.9 0.0 3.5 2 2 1 3 3 3 2 Malectin domain LRR_8 PF13855.6 GBG76929.1 - 2.8e-06 27.0 6.2 2.8e-06 27.0 6.2 1.8 2 0 0 2 2 2 1 Leucine rich repeat DUF3446 PF11928.8 GBG76929.1 - 0.0075 16.5 11.1 0.0075 16.5 11.1 2.9 2 0 0 2 2 2 1 Early growth response N-terminal domain LRRNT_2 PF08263.12 GBG76929.1 - 0.013 15.8 0.8 0.013 15.8 0.8 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain ABC1 PF03109.16 GBG76929.1 - 0.048 13.8 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC1 family DUF202 PF02656.15 GBG76929.1 - 0.11 12.9 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) LRR_4 PF12799.7 GBG76929.1 - 0.14 12.7 3.4 0.17 12.4 0.2 2.5 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) APH PF01636.23 GBG76929.1 - 0.19 11.6 0.0 0.44 10.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_1 PF00560.33 GBG76929.1 - 0.42 11.3 2.1 99 4.1 0.2 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat AA_permease_2 PF13520.6 GBG76930.1 - 5e-49 167.3 34.7 5e-49 167.3 34.7 1.4 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 GBG76930.1 - 4.5e-29 101.4 30.1 4.5e-29 101.4 30.1 1.8 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 GBG76930.1 - 2.2e-15 56.5 7.5 4.5e-15 55.5 4.7 3.0 2 0 0 2 2 2 1 C-terminus of AA_permease Spore_permease PF03845.13 GBG76930.1 - 0.0046 15.8 4.3 0.0046 15.8 4.3 2.7 3 0 0 3 3 3 2 Spore germination protein DUF3021 PF11457.8 GBG76930.1 - 0.016 15.5 4.0 0.016 15.5 4.0 4.2 5 1 1 6 6 6 0 Protein of unknown function (DUF3021) zf-RVT PF13966.6 GBG76931.1 - 4.4e-11 43.3 3.1 4.8e-11 43.2 0.9 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DNA_pol_lambd_f PF10391.9 GBG76931.1 - 0.071 13.0 1.8 5.1 7.0 0.2 3.2 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda Ribosomal_L32p PF01783.23 GBG76932.1 - 7.7e-14 51.7 2.5 7.7e-14 51.7 2.5 1.7 2 0 0 2 2 2 1 Ribosomal L32p protein family Yae1_N PF09811.9 GBG76932.1 - 1.7e-10 40.4 3.8 2.8e-10 39.7 3.8 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Myb_DNA-bind_4 PF13837.6 GBG76933.1 - 0.00038 20.8 1.0 0.00078 19.8 1.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG76933.1 - 0.19 11.8 0.3 0.36 10.9 0.3 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Cpn60_TCP1 PF00118.24 GBG76934.1 - 5.1e-105 351.9 19.3 9.9e-105 351.0 19.3 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family End_beta_barrel PF12195.8 GBG76934.1 - 0.037 14.0 0.5 0.44 10.5 0.2 2.7 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase UBA_6 PF18039.1 GBG76935.1 - 0.23 11.4 0.3 24 5.0 0.1 2.4 1 1 1 2 2 2 0 UBA-like domain Pkinase_Tyr PF07714.17 GBG76936.1 - 4.4e-43 147.4 0.0 8.5e-43 146.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG76936.1 - 1.2e-42 146.1 0.0 1.7e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain B_lectin PF01453.24 GBG76936.1 - 0.044 14.3 0.0 12 6.5 0.0 2.7 2 0 0 2 2 2 0 D-mannose binding lectin Dala_Dala_lig_N PF01820.21 GBG76936.1 - 0.11 13.0 0.0 0.48 10.9 0.0 2.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Radial_spoke PF04712.12 GBG76936.1 - 0.14 11.1 4.7 0.21 10.5 4.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Cytomega_UL84 PF06284.11 GBG76936.1 - 0.26 9.7 6.2 0.45 8.9 6.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CENP-B_dimeris PF09026.10 GBG76936.1 - 3.6 8.0 6.1 8.5 6.8 6.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RVT_1 PF00078.27 GBG76937.1 - 1e-33 116.7 0.1 1.8e-33 115.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG76937.1 - 6.1e-20 71.1 0.0 1.6e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG76937.1 - 2.6e-07 30.5 0.0 5.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG76937.1 - 7.1e-07 29.5 0.0 2.5e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG76937.1 - 2.3e-05 24.9 0.0 7e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG76937.1 - 2.5e-05 24.1 0.0 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG76937.1 - 4.4e-05 24.0 0.0 9.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ABC_tran_CTD PF16326.5 GBG76938.1 - 0.008 16.4 2.5 0.057 13.7 0.4 3.0 2 0 0 2 2 2 1 ABC transporter C-terminal domain CCD48 PF15799.5 GBG76938.1 - 0.011 14.1 5.6 0.02 13.2 5.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF2385 PF09539.10 GBG76938.1 - 0.047 14.2 0.1 1.6 9.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) DUF1216 PF06746.11 GBG76938.1 - 0.22 11.6 1.2 0.54 10.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) zf-CCHC_2 PF13696.6 GBG76938.1 - 0.6 10.0 3.2 0.93 9.4 3.2 1.3 1 0 0 1 1 1 0 Zinc knuckle PTPRCAP PF15713.5 GBG76939.1 - 0.022 15.0 0.2 0.035 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RVT_1 PF00078.27 GBG76940.1 - 5.2e-30 104.6 0.1 9.1e-30 103.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG76940.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG76940.1 - 0.0035 17.5 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG76940.1 - 0.023 14.5 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease APG17 PF04108.12 GBG76940.1 - 0.025 13.7 0.3 0.76 8.8 0.1 2.2 2 0 0 2 2 2 0 Autophagy protein Apg17 Retrotrans_gag PF03732.17 GBG76940.1 - 0.053 13.8 1.0 0.15 12.3 0.1 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein LrgB PF04172.16 GBG76941.1 - 1.7e-34 119.3 7.0 2.1e-34 118.9 7.0 1.0 1 0 0 1 1 1 1 LrgB-like family Sugar_tr PF00083.24 GBG76941.1 - 0.011 14.7 1.7 0.014 14.3 1.7 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter CBS PF00571.28 GBG76942.1 - 1.8e-27 95.5 2.5 7.7e-16 58.3 0.2 2.3 2 0 0 2 2 2 2 CBS domain PRC PF05239.16 GBG76942.1 - 0.29 11.2 2.6 14 5.8 0.1 2.9 3 0 0 3 3 3 0 PRC-barrel domain FAM199X PF15814.5 GBG76942.1 - 8.6 5.3 11.4 18 4.3 11.4 1.4 1 0 0 1 1 1 0 Protein family FAM199X SNF2_N PF00176.23 GBG76943.1 - 3.8e-67 226.5 0.1 7.3e-67 225.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG76943.1 - 9.2e-17 61.4 0.0 2.6e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SnAC PF14619.6 GBG76943.1 - 2.7e-08 34.3 0.5 2.7e-08 34.3 0.5 3.7 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex RT_RNaseH PF17917.1 GBG76944.1 - 2.7e-27 95.1 0.0 5.4e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG76944.1 - 2.8e-27 94.7 0.0 2.8e-13 49.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76944.1 - 1.8e-24 86.5 0.0 3e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG76944.1 - 2.6e-08 33.8 0.0 6.1e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain QLQ PF08880.11 GBG76945.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 QLQ Histone PF00125.24 GBG76948.1 - 5.6e-08 33.2 0.1 5.6e-08 33.2 0.1 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF3553 PF12073.8 GBG76948.1 - 0.41 10.4 2.5 0.32 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3553) VasL PF12486.8 GBG76949.1 - 0.0016 18.3 0.2 0.0039 17.1 0.2 1.7 1 0 0 1 1 1 1 Type VI secretion system, EvfB, or VasL XPG_I PF00867.18 GBG76949.1 - 0.055 13.8 0.6 0.29 11.5 0.0 2.3 2 1 0 2 2 2 0 XPG I-region COMP PF11598.8 GBG76949.1 - 0.41 11.1 5.0 6.3 7.4 0.1 2.8 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Fib_alpha PF08702.10 GBG76949.1 - 0.44 10.7 5.8 0.7 10.1 0.5 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 GBG76949.1 - 0.84 10.3 8.3 5.3 7.7 1.0 2.7 2 1 0 2 2 2 0 Initiation control protein YabA OmpH PF03938.14 GBG76949.1 - 1.2 9.5 7.2 0.38 11.1 1.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HR1 PF02185.16 GBG76949.1 - 1.6 8.9 9.1 0.19 11.8 1.3 2.8 2 1 0 2 2 2 0 Hr1 repeat SlyX PF04102.12 GBG76949.1 - 7.1 7.3 7.8 7.1 7.3 0.8 3.3 2 1 1 3 3 3 0 SlyX HD-ZIP_N PF04618.12 GBG76952.1 - 0.17 12.4 0.3 7 7.2 0.2 2.7 2 0 0 2 2 2 0 HD-ZIP protein N terminus RT_RNaseH_2 PF17919.1 GBG76953.1 - 3e-30 104.2 0.0 8.5e-30 102.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76953.1 - 8.9e-26 90.8 0.0 1.6e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76953.1 - 1.9e-21 76.3 0.0 5.9e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76953.1 - 2.2e-18 66.5 0.0 4.6e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Cytochrom_C PF00034.21 GBG76953.1 - 1.9e-11 44.9 0.0 5.3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 GBG76953.1 - 1.6e-05 25.1 2.3 6.6e-05 23.2 2.3 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GBG76953.1 - 0.0026 17.5 0.3 0.064 13.0 0.1 2.6 2 0 0 2 2 2 1 Cytochrome c-550 domain Phage_GPO PF05929.11 GBG76953.1 - 0.007 16.0 4.4 2 7.9 2.3 2.4 2 0 0 2 2 2 2 Phage capsid scaffolding protein (GPO) serine peptidase YabA PF06156.13 GBG76953.1 - 0.12 13.0 0.2 0.55 10.9 0.1 2.2 2 0 0 2 2 2 0 Initiation control protein YabA RVT_1 PF00078.27 GBG76955.1 - 6.8e-29 101.0 0.2 1.8e-28 99.6 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG76955.1 - 1.3e-08 34.7 0.0 2.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG76955.1 - 5.6e-08 33.3 0.0 2.1e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76955.1 - 7.7e-07 29.6 0.0 3.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG76955.1 - 8.6e-07 29.2 0.0 2.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG76955.1 - 9.9e-07 28.8 1.1 2.2e-06 27.7 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG76955.1 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG76955.1 - 0.053 13.8 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein SlyX PF04102.12 GBG76955.1 - 0.7 10.6 4.2 3.9 8.2 0.6 3.1 2 0 0 2 2 2 0 SlyX RT_RNaseH_2 PF17919.1 GBG76956.1 - 1.7e-26 92.2 0.0 3.9e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76956.1 - 7.5e-26 91.0 0.1 1.3e-25 90.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76956.1 - 7.1e-23 80.9 0.0 1.5e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG76956.1 - 0.62 8.3 8.7 0.88 7.8 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG76956.1 - 1.2 7.2 11.6 2.2 6.4 11.6 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG76956.1 - 1.3 8.4 10.6 2 7.7 10.6 1.2 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 GBG76956.1 - 1.3 9.3 13.0 2.3 8.5 13.0 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated ATP-synt_F PF01990.17 GBG76957.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit APO_RNA-bind PF05634.11 GBG76958.1 - 2.3e-59 200.1 0.9 7.2e-34 116.9 0.3 2.2 2 0 0 2 2 2 2 APO RNA-binding PTPRCAP PF15713.5 GBG76958.1 - 0.035 14.4 4.4 0.086 13.1 4.4 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated UPF0449 PF15136.6 GBG76959.1 - 0.28 11.7 14.5 1.4 9.4 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 NP1-WLL PF11733.8 GBG76959.1 - 1.6 8.5 7.2 3.3 7.4 7.2 1.5 1 0 0 1 1 1 0 Non-capsid protein NP1 CENP-N PF05238.13 GBG76961.1 - 0.11 11.8 2.4 0.25 10.6 0.4 2.2 2 1 1 3 3 3 0 Kinetochore protein CHL4 like Casc1_N PF15927.5 GBG76961.1 - 2.3 7.8 9.3 73 3.0 0.0 2.6 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Ferritin PF00210.24 GBG76962.1 - 2.3e-31 108.7 1.9 3.1e-31 108.2 1.9 1.2 1 0 0 1 1 1 1 Ferritin-like domain Presenilin PF01080.17 GBG76963.1 - 0.019 13.8 0.7 0.017 13.9 0.7 1.0 1 0 0 1 1 1 0 Presenilin DUF4366 PF14283.6 GBG76963.1 - 0.054 13.5 2.7 0.077 13.0 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SpoIIP PF07454.11 GBG76963.1 - 0.097 12.1 2.7 0.094 12.2 2.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RNA_polI_A34 PF08208.11 GBG76963.1 - 0.33 11.0 10.4 0.38 10.8 10.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 IDO PF01231.18 GBG76963.1 - 5.5 5.7 4.8 9.1 4.9 4.8 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase PPL5 PF18168.1 GBG76963.1 - 9.8 5.4 5.8 11 5.2 5.8 1.0 1 0 0 1 1 1 0 Prim-pol family 5 DUF659 PF04937.15 GBG76964.1 - 8.2e-33 113.4 0.0 1.4e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Na_sulph_symp PF00939.19 GBG76965.1 - 4.7e-72 243.5 10.2 6e-72 243.2 10.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GBG76965.1 - 4.3e-09 36.0 11.4 4.3e-09 36.0 11.4 1.5 1 1 0 1 1 1 1 Citrate transporter RT_RNaseH_2 PF17919.1 GBG76966.1 - 4.3e-30 103.7 0.0 4.2e-28 97.3 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG76966.1 - 3.5e-24 85.6 0.1 9.2e-24 84.2 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG76966.1 - 1.4e-23 83.1 0.1 2e-21 76.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG76966.1 - 1.4e-18 67.2 0.0 3.4e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG76966.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain MFS_5 PF05631.14 GBG76968.1 - 1.1e-85 287.7 8.1 1.5e-85 287.2 8.1 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Hydrolase PF00702.26 GBG76969.1 - 9.2e-36 124.1 2.4 8.5e-35 120.9 2.4 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GBG76969.1 - 1.3e-35 122.6 0.4 1.3e-35 122.6 0.4 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 GBG76969.1 - 1.9e-26 92.3 5.2 2.8e-11 43.7 0.1 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GBG76969.1 - 0.00026 20.8 1.3 0.00074 19.3 1.3 1.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 GBG76969.1 - 0.065 13.6 1.8 0.88 10.0 0.1 3.1 3 0 0 3 3 3 0 BFD-like [2Fe-2S] binding domain DDE_Tnp_1_assoc PF13808.6 GBG76969.1 - 0.099 12.7 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 DDE_Tnp_1-associated HAD PF12710.7 GBG76969.1 - 0.11 12.9 0.1 3.4 8.0 0.0 2.5 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase tRNA-synt_2d PF01409.20 GBG76970.1 - 4.3e-82 275.3 0.0 7.3e-82 274.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 GBG76970.1 - 6.8e-18 64.7 1.7 1.5e-17 63.6 0.2 2.3 3 0 0 3 3 3 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 GBG76970.1 - 2e-11 43.5 0.1 4.5e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 GBG76970.1 - 1.1e-07 31.5 0.0 0.00013 21.5 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 GBG76970.1 - 0.0012 18.0 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 GBG76970.1 - 0.03 14.3 0.0 0.068 13.1 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 GBG76970.1 - 0.11 12.5 0.2 0.33 11.0 0.2 1.9 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Mpp10 PF04006.12 GBG76972.1 - 0.019 13.4 17.5 0.021 13.3 17.5 1.0 1 0 0 1 1 1 0 Mpp10 protein Sporozoite_P67 PF05642.11 GBG76972.1 - 0.024 12.7 9.5 0.027 12.6 9.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FRQ PF09421.10 GBG76972.1 - 0.14 10.1 6.6 0.15 10.0 6.6 1.0 1 0 0 1 1 1 0 Frequency clock protein Nop14 PF04147.12 GBG76972.1 - 0.21 9.7 16.5 0.22 9.7 16.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG76972.1 - 0.23 10.9 18.8 0.24 10.8 18.8 1.0 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GBG76972.1 - 0.36 9.9 17.9 0.36 9.9 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RPN2_C PF18004.1 GBG76972.1 - 0.4 10.6 10.8 0.43 10.5 10.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 GBG76972.1 - 0.43 8.6 19.0 0.45 8.6 19.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 GBG76972.1 - 0.7 8.4 19.3 0.79 8.2 19.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_polI_A34 PF08208.11 GBG76972.1 - 0.86 9.7 13.0 0.89 9.6 13.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PTPRCAP PF15713.5 GBG76972.1 - 0.96 9.7 20.3 1.1 9.6 20.3 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated TERB2 PF15101.6 GBG76972.1 - 0.97 9.4 5.0 0.96 9.5 5.0 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Paf1 PF03985.13 GBG76972.1 - 2.4 7.1 18.5 2.6 7.0 18.5 1.1 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.16 GBG76972.1 - 2.8 7.1 13.8 3.5 6.8 13.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit LAP1C PF05609.12 GBG76972.1 - 2.8 6.9 9.7 3 6.8 9.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) U79_P34 PF03064.16 GBG76972.1 - 3 7.1 12.9 3.2 7.1 12.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.14 GBG76972.1 - 3.1 6.0 17.2 3.5 5.8 17.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG76972.1 - 3.1 7.1 13.0 3.7 6.9 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 GBG76972.1 - 3.2 7.5 12.4 3.4 7.4 12.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PI3K_1B_p101 PF10486.9 GBG76972.1 - 4.1 5.1 7.5 4.2 5.0 7.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Connexin PF00029.19 GBG76972.1 - 6.9 6.4 6.4 6.9 6.3 6.4 1.1 1 0 0 1 1 1 0 Connexin Zip PF02535.22 GBG76972.1 - 7 5.8 5.7 7 5.8 5.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Mem_trans PF03547.18 GBG76972.1 - 7.1 4.9 5.3 8 4.7 5.3 1.0 1 0 0 1 1 1 0 Membrane transport protein Roughex PF06020.11 GBG76972.1 - 8.8 5.3 11.8 8.9 5.3 11.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF659 PF04937.15 GBG76973.1 - 5.4e-32 110.8 0.0 1.1e-31 109.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) MAJIN PF15077.6 GBG76973.1 - 6.6 6.5 9.2 11 5.7 9.2 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF2109 PF09882.9 GBG76974.1 - 4.5 7.4 4.8 61 3.7 0.0 3.9 3 1 0 3 3 3 0 Predicted membrane protein (DUF2109) RVT_1 PF00078.27 GBG76976.1 - 9.4e-08 31.8 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GLTT PF01744.20 GBG76976.1 - 0.00019 21.1 0.1 0.0067 16.1 0.0 2.7 3 0 0 3 3 3 1 GLTT repeat (6 copies) Histone PF00125.24 GBG76977.1 - 3.3e-26 92.2 0.4 3.3e-26 92.2 0.4 4.1 2 1 0 4 4 4 1 Core histone H2A/H2B/H3/H4 Plavaka PF18759.1 GBG76977.1 - 3.3e-26 92.3 0.2 6.1e-26 91.4 0.2 1.4 1 0 0 1 1 1 1 Plavaka transposase CENP-S PF15630.6 GBG76977.1 - 0.15 12.5 1.6 0.29 11.5 0.4 2.0 2 0 0 2 2 2 0 CENP-S protein ACT_4 PF13291.6 GBG76978.1 - 4.7e-11 43.1 0.0 0.38 11.4 0.0 4.3 4 0 0 4 4 4 4 ACT domain ACT PF01842.25 GBG76978.1 - 1.5e-10 40.6 0.0 0.02 14.7 0.0 4.3 4 0 0 4 4 4 3 ACT domain Dapper PF15268.6 GBG76978.1 - 0.013 14.4 10.8 0.019 13.9 10.8 1.2 1 0 0 1 1 1 0 Dapper SUIM_assoc PF16619.5 GBG76978.1 - 0.14 12.2 20.2 1.5 9.0 2.7 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Macoilin PF09726.9 GBG76978.1 - 0.15 10.6 8.9 0.22 10.0 8.9 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 GBG76978.1 - 0.29 9.9 6.7 0.5 9.1 6.7 1.4 1 0 0 1 1 1 0 Presenilin PPR PF01535.20 GBG76979.1 - 5.4e-83 267.6 22.6 2.2e-09 36.9 0.1 11.5 11 0 0 11 11 11 11 PPR repeat PPR_2 PF13041.6 GBG76979.1 - 1.2e-82 271.9 10.3 8.5e-15 54.7 0.0 10.2 3 3 7 10 10 10 10 PPR repeat family PPR_1 PF12854.7 GBG76979.1 - 3.7e-80 263.3 17.0 1.4e-10 40.6 0.0 11.7 12 0 0 12 12 12 11 PPR repeat PPR_3 PF13812.6 GBG76979.1 - 2.7e-68 225.9 2.9 1.6e-09 37.7 0.0 8.5 2 2 9 11 11 11 11 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG76979.1 - 1.7e-30 106.0 1.9 3.9e-09 36.2 0.0 4.3 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 GBG76979.1 - 4.3e-06 26.4 0.1 6.1 7.1 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG76979.1 - 5.3e-05 23.7 8.0 53 5.0 0.1 8.5 6 3 4 10 10 9 0 Tetratricopeptide repeat MRP-S27 PF10037.9 GBG76979.1 - 6.3e-05 22.0 0.1 3.2 6.5 0.0 4.3 2 2 2 4 4 4 2 Mitochondrial 28S ribosomal protein S27 Exog_C PF18026.1 GBG76979.1 - 6.8e-05 22.8 0.0 0.18 11.9 0.0 4.4 4 0 0 4 4 4 1 Endo/exonuclease (EXOG) C-terminal domain DUF3368 PF11848.8 GBG76979.1 - 0.011 15.4 0.1 11 5.9 0.0 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF3368) ECSIT PF06239.11 GBG76979.1 - 0.056 12.6 1.7 13 4.9 0.0 4.7 5 1 2 7 7 7 0 Evolutionarily conserved signalling intermediate in Toll pathway PYRIN PF02758.16 GBG76979.1 - 0.059 13.5 2.0 36 4.6 0.1 4.6 5 0 0 5 5 5 0 PAAD/DAPIN/Pyrin domain Wzy_C_2 PF11846.8 GBG76979.1 - 0.064 13.2 0.1 13 5.7 0.0 3.5 1 1 2 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Peptidase_M3_N PF08439.10 GBG76979.1 - 0.16 12.2 0.1 6.1 7.2 0.0 2.8 2 0 0 2 2 2 0 Oligopeptidase F BTAD PF03704.17 GBG76979.1 - 0.47 10.9 7.3 19 5.6 0.1 4.5 5 2 1 6 6 6 0 Bacterial transcriptional activator domain Nop53 PF07767.11 GBG76980.1 - 0.027 13.9 22.7 0.039 13.4 22.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Serinc PF03348.15 GBG76980.1 - 0.38 9.6 0.7 0.57 9.0 0.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) BUD22 PF09073.10 GBG76980.1 - 0.97 8.7 26.3 1.3 8.3 26.3 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GBG76980.1 - 1.4 8.6 23.3 1.9 8.2 23.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TMEM174 PF15029.6 GBG76980.1 - 1.9 8.2 3.9 0.58 9.8 0.5 1.8 1 1 1 2 2 2 0 Transmembrane protein 174 PPL5 PF18168.1 GBG76980.1 - 2.2 7.5 6.2 3.1 7.0 6.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 CDC45 PF02724.14 GBG76980.1 - 2.8 6.1 21.4 3.5 5.8 21.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG76980.1 - 7.1 6.0 30.6 9.5 5.5 30.6 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG76981.1 - 9.7 5.4 22.4 14 4.8 22.4 1.3 1 0 0 1 1 1 0 BUD22 Ins134_P3_kin PF05770.11 GBG76982.1 - 7.4e-79 263.9 0.0 1.9e-78 262.6 0.0 1.6 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 GBG76982.1 - 4.3e-25 87.9 0.1 8.9e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain HSP33 PF01430.19 GBG76983.1 - 2.9e-44 151.5 0.6 5.3e-18 65.4 0.0 3.5 2 1 1 3 3 3 3 Hsp33 protein Dimer_Tnp_hAT PF05699.14 GBG76984.1 - 3.7e-05 23.4 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG76984.1 - 0.07 13.0 0.4 0.16 11.9 0.4 1.6 1 0 0 1 1 1 0 AT hook motif AAA PF00004.29 GBG76986.1 - 1.2e-06 28.9 0.0 3.6e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GBG76986.1 - 1.2e-05 25.1 0.1 2.9e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GBG76986.1 - 1.7e-05 25.1 0.2 6.5e-05 23.2 0.0 2.0 2 1 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 GBG76986.1 - 1.7e-05 24.8 0.1 0.034 14.0 0.0 2.6 2 0 0 2 2 2 2 NTPase AAA_16 PF13191.6 GBG76986.1 - 1.9e-05 25.1 0.3 7.7e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 GBG76986.1 - 4.2e-05 24.1 0.0 0.00012 22.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GBG76986.1 - 0.00025 20.8 0.0 0.00064 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GBG76986.1 - 0.00068 19.6 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GBG76986.1 - 0.0016 17.9 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 GBG76986.1 - 0.0051 15.9 0.3 0.0083 15.2 0.3 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 GBG76986.1 - 0.009 16.4 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 GBG76986.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 GBG76986.1 - 0.015 15.1 2.3 0.019 14.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG76986.1 - 0.023 14.3 0.1 0.023 14.3 0.1 2.6 3 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 GBG76986.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 GBG76986.1 - 0.031 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 GBG76986.1 - 0.034 14.1 0.0 0.09 12.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 GBG76986.1 - 0.041 14.3 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 GBG76986.1 - 0.041 14.1 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GBG76986.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_31 PF13614.6 GBG76986.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PI3K_1B_p101 PF10486.9 GBG76986.1 - 0.065 11.0 16.3 0.18 9.6 11.8 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CbiA PF01656.23 GBG76986.1 - 0.08 13.0 0.0 0.36 10.9 0.0 2.0 2 1 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 GBG76986.1 - 0.089 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 GBG76986.1 - 0.1 12.8 1.1 0.2 11.9 0.0 2.1 2 1 0 2 2 1 0 AAA domain KTI12 PF08433.10 GBG76986.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 GBG76986.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 GBG76986.1 - 0.15 11.0 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 GBG76986.1 - 0.15 12.0 0.0 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GBG76986.1 - 0.16 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RuvB_N PF05496.12 GBG76986.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Apt1 PF10351.9 GBG76986.1 - 0.22 10.3 12.2 0.019 13.8 5.5 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain NB-ARC PF00931.22 GBG76986.1 - 0.25 10.5 0.6 0.63 9.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Secretin_N_2 PF07655.13 GBG76986.1 - 0.97 10.0 13.8 1.2 9.7 10.0 2.8 2 0 0 2 2 2 0 Secretin N-terminal domain NOA36 PF06524.12 GBG76986.1 - 2.2 7.5 22.0 2.9 7.1 12.4 2.4 2 0 0 2 2 2 0 NOA36 protein DUF4551 PF15087.6 GBG76986.1 - 7.6 5.2 7.3 14 4.4 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2514 PF10721.9 GBG76987.1 - 0.21 11.6 8.4 0.4 10.7 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) gag-asp_proteas PF13975.6 GBG76988.1 - 1.5e-06 28.6 0.4 5.6e-06 26.8 0.1 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG76988.1 - 1.6e-06 28.6 0.1 5e-06 27.1 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG76988.1 - 7.8e-05 22.5 0.1 0.00016 21.5 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG76988.1 - 0.031 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Sucrose_synth PF00862.19 GBG76990.1 - 1.9e-254 845.1 0.0 2.3e-254 844.8 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG76990.1 - 1.8e-28 99.2 0.0 3.1e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG76990.1 - 2.1e-10 41.1 0.0 5.3e-10 39.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG76990.1 - 8.8e-05 22.8 0.0 0.00026 21.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pox_D5 PF03288.16 GBG76990.1 - 0.046 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like Myb_DNA-bind_4 PF13837.6 GBG76991.1 - 4.8e-09 36.5 0.3 4.8e-09 36.5 0.3 2.2 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Na_trans_assoc PF06512.13 GBG76991.1 - 0.00015 22.1 12.0 0.00015 22.1 12.0 2.2 3 0 0 3 3 3 1 Sodium ion transport-associated MADF_DNA_bdg PF10545.9 GBG76991.1 - 0.0019 18.5 0.0 0.0073 16.6 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like NPR3 PF03666.13 GBG76991.1 - 0.09 11.6 2.5 0.17 10.7 2.5 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Myb_DNA-bind_5 PF13873.6 GBG76991.1 - 0.12 12.5 0.5 0.35 11.0 0.5 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Nop25 PF09805.9 GBG76991.1 - 0.93 10.0 21.6 7.7 7.0 10.2 3.7 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) Presenilin PF01080.17 GBG76991.1 - 3.4 6.4 4.2 4.9 5.8 4.2 1.4 1 0 0 1 1 1 0 Presenilin PALP PF00291.25 GBG76993.1 - 1.2e-53 182.4 0.2 1.4e-53 182.2 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FragX_IP PF05994.11 GBG76995.1 - 1.2e-71 241.9 0.0 1.3e-71 241.8 0.0 1.0 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family RVP_2 PF08284.11 GBG76996.1 - 1.3e-07 31.5 0.0 3.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG76996.1 - 8.8e-07 28.7 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG76996.1 - 4.5e-05 24.0 0.0 0.00012 22.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG76996.1 - 0.00052 20.5 0.2 0.0037 17.8 0.0 2.5 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG76996.1 - 0.0012 18.6 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG76996.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Casc1_N PF15927.5 GBG76996.1 - 0.11 12.1 8.9 0.31 10.7 8.9 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus FragX_IP PF05994.11 GBG76997.1 - 1.7e-58 198.5 0.0 2.2e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 GBG76997.1 - 2.3e-10 40.2 0.0 7e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) CDC45 PF02724.14 GBG76999.1 - 0.039 12.2 15.6 0.044 12.1 15.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG76999.1 - 0.06 11.4 10.7 0.055 11.6 10.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG76999.1 - 0.39 8.9 13.6 0.45 8.7 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 GBG76999.1 - 1.6 8.1 12.2 2.1 7.7 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RRN3 PF05327.11 GBG76999.1 - 1.9 6.9 4.7 1.9 6.9 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 GBG76999.1 - 3 6.5 7.0 3.4 6.3 7.0 1.0 1 0 0 1 1 1 0 Presenilin HSP90 PF00183.18 GBG76999.1 - 6.9 5.4 11.2 9.6 5.0 11.2 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF4746 PF15928.5 GBG76999.1 - 8.8 5.7 12.0 14 5.0 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PALP PF00291.25 GBG77000.1 - 2.1e-65 221.1 0.5 2.5e-65 220.8 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tmemb_14 PF03647.13 GBG77000.1 - 0.7 10.7 3.4 25 5.7 0.1 2.7 3 0 0 3 3 3 0 Transmembrane proteins 14C FAM76 PF16046.5 GBG77001.1 - 0.27 10.6 1.7 0.33 10.3 1.7 1.1 1 0 0 1 1 1 0 FAM76 protein ANAPC4_WD40 PF12894.7 GBG77002.1 - 5.6e-12 45.8 0.3 2.5e-07 30.9 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GBG77002.1 - 2.2e-11 44.1 8.0 2.1e-06 28.4 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GBG77002.1 - 0.00012 21.2 0.2 0.43 9.5 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GBG77002.1 - 0.013 14.3 0.0 0.99 8.1 0.0 2.3 2 1 0 2 2 2 0 Nup133 N terminal like ANAPC4_WD40 PF12894.7 GBG77003.1 - 5.7e-12 45.8 0.3 2.6e-07 30.9 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GBG77003.1 - 2.4e-11 44.0 8.2 2.1e-06 28.4 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GBG77003.1 - 0.00011 21.2 0.2 0.43 9.5 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GBG77003.1 - 0.013 14.3 0.0 1 8.0 0.0 2.3 2 1 0 2 2 2 0 Nup133 N terminal like zf-RING_2 PF13639.6 GBG77004.1 - 7.7e-11 42.1 3.8 7.7e-11 42.1 3.8 2.2 2 0 0 2 2 2 1 Ring finger domain zinc_ribbon_9 PF14369.6 GBG77004.1 - 2.4e-08 34.1 0.5 2.4e-08 34.1 0.5 2.4 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_2 PF13923.6 GBG77004.1 - 3.7e-08 33.1 3.5 3.7e-08 33.1 3.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG77004.1 - 5.8e-08 32.3 0.6 1.3e-07 31.2 0.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GBG77004.1 - 1.3e-06 28.6 6.2 1.3e-06 28.6 6.2 2.0 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GBG77004.1 - 1.2e-05 25.0 2.7 1.2e-05 25.0 2.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG77004.1 - 0.0004 20.3 0.4 0.001 19.1 0.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GBG77004.1 - 0.00088 19.3 0.7 0.0019 18.2 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GBG77004.1 - 0.002 17.9 8.2 0.0042 16.9 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 GBG77004.1 - 0.018 15.4 3.4 0.04 14.2 3.4 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 GBG77004.1 - 0.068 13.2 11.0 0.36 10.9 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger zf-RING_5 PF14634.6 GBG77004.1 - 0.076 13.0 10.8 0.038 13.9 3.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG77004.1 - 1 9.2 10.6 0.08 12.8 3.5 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.7 GBG77004.1 - 9.6 6.3 8.6 1.3 9.1 0.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon Prp18 PF02840.15 GBG77005.1 - 8.9e-63 210.6 0.2 8.9e-63 210.6 0.2 1.6 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 GBG77005.1 - 7.6e-13 47.8 2.5 2e-12 46.4 2.5 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF3379 PF11859.8 GBG77005.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Nop14 PF04147.12 GBG77006.1 - 0.12 10.6 54.2 0.18 10.0 54.2 1.3 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 GBG77006.1 - 4.4 6.0 15.3 6.8 5.4 15.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ribosomal_L11_N PF03946.14 GBG77007.1 - 2.1e-28 97.9 1.4 4.7e-28 96.8 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 GBG77007.1 - 1.2e-17 64.1 0.4 2.5e-17 63.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain GST_C_2 PF13410.6 GBG77007.1 - 0.023 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Snf7 PF03357.21 GBG77008.1 - 1.9e-32 112.2 15.1 3.1e-32 111.5 15.1 1.3 1 0 0 1 1 1 1 Snf7 RVT_1 PF00078.27 GBG77009.1 - 4.5e-07 29.6 0.0 7.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAGAT PF03982.13 GBG77010.1 - 7.5e-56 189.2 0.0 9.1e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase ABC_tran PF00005.27 GBG77011.1 - 2.1e-37 128.7 0.0 1.7e-17 64.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 GBG77011.1 - 4.5e-14 52.0 5.9 1.2e-13 50.6 5.9 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 GBG77011.1 - 6.4e-13 48.7 6.0 3.9e-05 23.2 0.7 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GBG77011.1 - 5.4e-11 42.8 2.4 0.0075 16.1 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 GBG77011.1 - 5.6e-09 35.4 3.4 5.6e-09 35.4 3.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 GBG77011.1 - 4.5e-06 27.1 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GBG77011.1 - 5.4e-06 26.4 0.2 0.00099 19.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 GBG77011.1 - 6.2e-06 26.8 0.0 0.023 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GBG77011.1 - 6.6e-06 26.1 0.1 0.055 13.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Fer4_6 PF12837.7 GBG77011.1 - 1.3e-05 25.0 3.0 1.3e-05 25.0 3.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 GBG77011.1 - 2.2e-05 24.1 0.3 0.2 11.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 GBG77011.1 - 2.3e-05 24.3 3.9 0.1 12.3 0.0 3.6 3 1 1 4 4 4 1 AAA ATPase domain Rad17 PF03215.15 GBG77011.1 - 3.4e-05 23.9 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 GBG77011.1 - 4.2e-05 24.0 0.0 0.26 11.7 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GBG77011.1 - 0.00017 21.9 0.0 0.056 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 GBG77011.1 - 0.00032 20.8 11.5 0.00063 19.8 11.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 GBG77011.1 - 0.00034 20.5 0.7 0.00034 20.5 0.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 GBG77011.1 - 0.0004 20.6 0.1 0.51 10.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 GBG77011.1 - 0.00059 19.6 0.1 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 GBG77011.1 - 0.0007 19.6 0.1 0.045 13.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 GBG77011.1 - 0.0011 18.7 3.3 0.16 11.6 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Fer4_7 PF12838.7 GBG77011.1 - 0.0013 19.2 1.3 0.0013 19.2 1.3 2.4 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GBG77011.1 - 0.0014 18.7 1.2 0.0014 18.7 1.2 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain RNA_helicase PF00910.22 GBG77011.1 - 0.0025 18.2 0.0 4.3 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 GBG77011.1 - 0.0035 17.1 0.2 0.54 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 GBG77011.1 - 0.0049 17.0 12.0 0.0095 16.1 12.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_5 PF07728.14 GBG77011.1 - 0.0061 16.6 0.9 0.37 10.8 0.1 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 GBG77011.1 - 0.0077 15.5 0.1 0.64 9.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Thymidylate_kin PF02223.17 GBG77011.1 - 0.0099 15.6 0.1 3.7 7.2 0.0 3.0 3 0 0 3 3 2 1 Thymidylate kinase Fer4_16 PF13484.6 GBG77011.1 - 0.012 16.5 0.2 0.012 16.5 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_7 PF12775.7 GBG77011.1 - 0.014 14.9 0.2 1.3 8.5 0.0 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 GBG77011.1 - 0.015 15.5 0.0 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GBG77011.1 - 0.024 15.2 0.0 5.8 7.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GBG77011.1 - 0.027 14.4 2.1 4.2 7.2 0.0 3.2 3 0 0 3 3 3 0 NTPase DUF815 PF05673.13 GBG77011.1 - 0.045 12.9 0.1 8.9 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 GBG77011.1 - 0.075 13.1 0.3 26 4.9 0.0 3.2 2 1 1 3 3 3 0 AAA domain Mg_chelatase PF01078.21 GBG77011.1 - 0.088 12.2 0.5 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 GBG77011.1 - 0.11 12.5 1.9 14 5.8 0.4 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Septin PF00735.18 GBG77011.1 - 0.12 11.7 0.0 5.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Septin Fer4_8 PF13183.6 GBG77011.1 - 0.13 12.8 0.1 0.13 12.8 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain MeaB PF03308.16 GBG77011.1 - 0.14 11.1 0.7 0.59 9.1 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 GBG77011.1 - 0.15 12.3 0.0 11 6.4 0.0 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TniB PF05621.11 GBG77011.1 - 0.21 11.0 0.5 16 4.9 0.0 3.0 2 1 0 3 3 3 0 Bacterial TniB protein MukB PF04310.12 GBG77011.1 - 0.31 10.8 1.7 19 4.9 0.0 2.6 3 0 0 3 3 2 0 MukB N-terminal Fer4_4 PF12800.7 GBG77011.1 - 1.3 9.7 16.5 0.13 12.8 2.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain DEAD PF00270.29 GBG77012.1 - 8.9e-12 45.1 0.4 4.7e-11 42.8 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG77012.1 - 0.00063 20.1 0.1 0.015 15.6 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain GSH-S_ATP PF02955.16 GBG77012.1 - 0.033 13.6 0.1 0.082 12.3 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Anti-TRAP PF15777.5 GBG77013.1 - 0.014 15.3 0.2 0.98 9.4 0.0 2.8 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ_CXXCXGXG PF00684.19 GBG77013.1 - 0.034 14.5 0.8 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 DnaJ central domain DUF3439 PF11921.8 GBG77013.1 - 0.066 13.2 9.5 0.18 11.8 9.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Asparaginase PF00710.20 GBG77013.1 - 0.068 12.7 0.4 0.12 11.9 0.4 1.4 1 0 0 1 1 1 0 Asparaginase, N-terminal Dicty_REP PF05086.12 GBG77013.1 - 2.5 6.0 3.6 3.3 5.6 3.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PIP5K PF01504.18 GBG77014.1 - 3.8e-90 301.8 0.0 9.3e-90 300.6 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase MORN PF02493.20 GBG77014.1 - 1.1e-45 150.9 54.9 1.2e-06 28.1 1.1 9.6 9 0 0 9 9 9 8 MORN repeat BSP_II PF05432.11 GBG77014.1 - 0.19 11.4 11.1 0.39 10.4 11.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 GBG77014.1 - 3.5 5.8 7.0 5.5 5.2 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein HMGL-like PF00682.19 GBG77015.1 - 1.3e-90 303.5 0.0 2.4e-90 302.7 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 GBG77015.1 - 6.5e-37 126.4 0.0 1.2e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain EFhand_Ca_insen PF08726.10 GBG77015.1 - 0.2 11.8 0.1 0.42 10.7 0.1 1.5 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DNA_ligase_aden PF01653.18 GBG77016.1 - 1.3e-90 303.8 1.5 4e-52 177.3 0.0 4.1 2 1 1 3 3 3 3 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 GBG77016.1 - 2.1e-27 94.8 0.2 5.4e-27 93.5 0.2 1.7 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 GBG77016.1 - 3.3e-19 68.7 0.0 1.4e-17 63.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GBG77016.1 - 6.1e-15 55.6 0.4 7.6e-07 29.6 0.0 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT PF00533.26 GBG77016.1 - 3e-14 53.1 0.0 6.4e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GBG77016.1 - 9.6e-07 28.7 0.1 2.1e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain HHH PF00633.23 GBG77016.1 - 2e-05 24.2 0.0 0.00055 19.7 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 GBG77016.1 - 0.00014 22.0 0.1 0.36 11.1 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 GBG77016.1 - 0.068 13.8 0.0 3.4 8.3 0.0 2.9 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold BRCT_2 PF16589.5 GBG77016.1 - 0.17 12.3 0.0 0.77 10.2 0.0 2.1 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_aden PF01653.18 GBG77017.1 - 1.2e-89 300.5 0.1 1.2e-60 205.3 0.0 3.2 2 1 0 2 2 2 2 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 GBG77017.1 - 2e-27 94.9 0.2 5.3e-27 93.5 0.2 1.7 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 GBG77017.1 - 3.1e-19 68.8 0.0 1.3e-17 63.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GBG77017.1 - 5.8e-15 55.6 0.4 7.4e-07 29.7 0.0 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT PF00533.26 GBG77017.1 - 2.9e-14 53.2 0.0 6.2e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GBG77017.1 - 9.2e-07 28.7 0.1 2e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain HHH PF00633.23 GBG77017.1 - 1.9e-05 24.3 0.0 0.00054 19.7 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 GBG77017.1 - 0.00013 22.1 0.1 0.34 11.2 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 GBG77017.1 - 0.072 13.7 0.0 3.3 8.4 0.0 2.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DNA_ligase_aden PF01653.18 GBG77018.1 - 1.2e-89 300.5 0.1 1.2e-60 205.3 0.0 3.2 2 1 0 2 2 2 2 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 GBG77018.1 - 2e-27 94.9 0.2 5.3e-27 93.5 0.2 1.7 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 GBG77018.1 - 3.1e-19 68.8 0.0 1.3e-17 63.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GBG77018.1 - 5.8e-15 55.6 0.4 7.4e-07 29.7 0.0 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT PF00533.26 GBG77018.1 - 2.9e-14 53.2 0.0 6.2e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GBG77018.1 - 9.2e-07 28.7 0.1 2e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain HHH PF00633.23 GBG77018.1 - 1.9e-05 24.3 0.0 0.00054 19.7 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 GBG77018.1 - 0.00013 22.1 0.1 0.34 11.2 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 GBG77018.1 - 0.072 13.7 0.0 3.3 8.4 0.0 2.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DNA_ligase_aden PF01653.18 GBG77019.1 - 2.1e-75 253.8 0.6 3.9e-52 177.3 0.0 4.2 2 1 1 3 3 3 3 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 GBG77019.1 - 2.1e-27 94.8 0.2 5.4e-27 93.5 0.2 1.7 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 GBG77019.1 - 3.3e-19 68.7 0.0 1.4e-17 63.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GBG77019.1 - 6.1e-15 55.6 0.4 7.6e-07 29.6 0.0 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT PF00533.26 GBG77019.1 - 2.9e-14 53.2 0.0 6.4e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GBG77019.1 - 9.5e-07 28.7 0.1 2.1e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain HHH PF00633.23 GBG77019.1 - 1.9e-05 24.3 0.0 0.00055 19.7 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 GBG77019.1 - 0.00014 22.1 0.1 0.35 11.1 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 GBG77019.1 - 0.068 13.8 0.0 3.4 8.3 0.0 2.9 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold BRCT_2 PF16589.5 GBG77019.1 - 0.17 12.3 0.0 0.77 10.2 0.0 2.1 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain AMPK1_CBM PF16561.5 GBG77020.1 - 5.1e-18 65.1 0.0 8.1e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 GBG77020.1 - 3.1e-06 27.5 0.0 5.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF1664 PF07889.12 GBG77020.1 - 0.0045 17.0 0.1 0.0079 16.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CBM53 PF16760.5 GBG77020.1 - 0.0077 16.8 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) AMPK1_CBM PF16561.5 GBG77021.1 - 5.3e-18 65.0 0.0 8.5e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 GBG77021.1 - 2.8e-06 27.6 0.0 6.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 GBG77021.1 - 0.0075 16.8 0.0 0.02 15.5 0.0 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) MIP-T3_C PF17749.1 GBG77021.1 - 0.31 11.0 5.3 5 7.1 0.1 2.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Proteasome PF00227.26 GBG77023.1 - 1.7e-47 161.4 0.0 2e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RT_RNaseH_2 PF17919.1 GBG77024.1 - 3.2e-26 91.3 0.0 5.7e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77024.1 - 5.4e-15 55.6 0.0 1.6e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77024.1 - 2.8e-11 43.3 0.1 5.4e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG77024.1 - 0.075 11.2 6.6 0.11 10.8 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family Fer2_3 PF13085.6 GBG77024.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain CDC45 PF02724.14 GBG77024.1 - 0.69 8.1 9.7 0.91 7.7 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG77024.1 - 0.81 9.1 10.3 1.1 8.6 10.3 1.1 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG77025.1 - 4.4e-45 153.9 0.7 8.4e-26 90.9 0.1 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77025.1 - 2.7e-36 123.5 3.3 3.2e-17 62.4 0.2 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG77025.1 - 2.3e-28 98.6 1.4 1.4e-18 67.0 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77025.1 - 2.2e-16 59.7 0.0 2.8e-11 43.3 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77025.1 - 4.2e-11 43.1 0.3 2.2e-10 40.7 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain Asp_protease_2 PF13650.6 GBG77025.1 - 6.4e-06 26.7 0.0 1.9e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77025.1 - 1.7e-05 25.3 0.0 3.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77025.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG77025.1 - 0.00021 21.5 0.0 0.0012 19.0 0.0 2.4 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG77025.1 - 0.0026 17.6 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG77025.1 - 0.062 13.5 0.1 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 H2C2 zinc finger LRAT PF04970.13 GBG77026.1 - 1.8e-26 92.9 0.0 3e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 GBG77026.1 - 0.061 13.4 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 NlpC/P60 family Nudix_hydro PF18290.1 GBG77027.1 - 2.6e-26 91.4 0.0 5.9e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 GBG77027.1 - 1.7e-19 70.1 0.0 2.8e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ELP6 PF09807.9 GBG77028.1 - 1.3e-29 103.4 1.8 1.3e-16 60.8 0.5 3.2 3 0 0 3 3 3 3 Elongation complex protein 6 Elong_Iki1 PF10483.9 GBG77028.1 - 8e-06 25.6 0.0 0.001 18.7 0.0 2.3 2 0 0 2 2 2 2 Elongator subunit Iki1 ATPase PF06745.13 GBG77028.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.5 2 0 0 2 2 2 0 KaiC Myc_N PF01056.18 GBG77030.1 - 0.18 11.6 4.6 0.21 11.4 4.6 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 GBG77030.1 - 0.74 7.9 4.6 0.73 8.0 4.6 1.0 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.6 GBG77030.1 - 0.96 9.3 5.0 0.96 9.4 5.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Paf1 PF03985.13 GBG77030.1 - 1.5 7.8 6.7 1.5 7.8 6.7 1.0 1 0 0 1 1 1 0 Paf1 Nop53 PF07767.11 GBG77030.1 - 3.6 6.9 11.0 4 6.7 11.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Tic110 PF16940.5 GBG77030.1 - 4.1 5.8 8.6 4.7 5.6 8.6 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter Ribosomal_60s PF00428.19 GBG77030.1 - 4.3 8.0 49.6 7.1 7.3 28.7 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein Glyco_hydro_38N PF01074.22 GBG77031.1 - 5.7e-88 295.0 4.2 7.8e-88 294.6 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GBG77031.1 - 2.7e-47 161.6 0.0 4.4e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GBG77031.1 - 1.1e-18 67.2 0.2 2.3e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GBG77031.1 - 4.2e-06 26.8 0.2 1.1e-05 25.4 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF3473 PF11959.8 GBG77031.1 - 0.076 13.0 0.0 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3473) Tcp10_C PF07202.13 GBG77032.1 - 1.3e-20 74.0 0.1 1.3e-20 74.0 0.1 3.6 5 0 0 5 5 5 1 T-complex protein 10 C-terminus SUIM_assoc PF16619.5 GBG77032.1 - 3.4 7.8 43.9 0.69 10.0 8.5 4.4 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 zf-CCHC PF00098.23 GBG77033.1 - 1.4e-06 28.1 0.5 2.8e-06 27.2 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG77033.1 - 0.012 15.3 0.5 0.035 13.9 0.5 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG77033.1 - 0.021 14.7 0.2 0.047 13.5 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1943 PF09172.11 GBG77033.1 - 1.4 8.1 3.9 2.5 7.3 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DXP_reductoisom PF02670.16 GBG77033.1 - 2.1 9.1 5.2 1.4 9.6 0.5 2.6 2 1 1 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DNApol_Exo PF18136.1 GBG77033.1 - 8.2 5.5 6.6 2.3 7.3 3.5 1.6 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain Glyco_transf_34 PF05637.12 GBG77034.1 - 7.9e-23 81.4 0.0 5.9e-14 52.4 0.1 2.2 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family DAHP_synth_2 PF01474.16 GBG77036.1 - 1.7e-196 653.0 0.0 2e-196 652.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Glyco_transf_5 PF08323.11 GBG77039.1 - 2.9e-62 210.6 0.1 4.3e-62 210.0 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG77039.1 - 2e-13 50.3 0.0 3.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG77039.1 - 2.1e-11 44.4 0.0 3.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG77039.1 - 0.0061 16.6 0.5 0.067 13.2 0.1 2.5 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GBG77039.1 - 0.021 15.2 0.2 0.083 13.3 0.2 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain NYN PF01936.18 GBG77039.1 - 0.089 13.3 0.0 0.32 11.5 0.0 1.9 2 0 0 2 2 2 0 NYN domain DUF659 PF04937.15 GBG77041.1 - 2.9e-25 88.9 0.2 4.4e-25 88.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG77041.1 - 7.9e-06 25.6 0.2 1.6e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Drc1-Sld2 PF11719.8 GBG77041.1 - 0.038 13.6 4.8 0.058 12.9 4.8 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein CDC45 PF02724.14 GBG77041.1 - 0.2 9.9 10.5 0.29 9.4 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG77041.1 - 0.63 9.4 13.9 1.2 8.5 13.9 1.4 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 GBG77041.1 - 0.66 9.9 5.6 1.1 9.1 5.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 GBG77041.1 - 0.71 9.1 8.3 1.6 8.0 8.3 1.6 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GBG77041.1 - 1.8 6.7 14.4 2.6 6.2 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG77041.1 - 6.6 4.7 18.8 9.5 4.2 18.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 GBG77041.1 - 9 5.6 14.6 19 4.5 14.6 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 GBG77042.1 - 0.0028 17.0 20.2 0.0036 16.7 20.2 1.1 1 0 0 1 1 1 1 BUD22 Prothymosin PF03247.14 GBG77042.1 - 0.1 13.1 38.2 0.75 10.3 8.8 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family NOA36 PF06524.12 GBG77042.1 - 0.11 11.8 23.1 0.19 11.0 12.3 2.2 2 0 0 2 2 2 0 NOA36 protein YL1 PF05764.13 GBG77042.1 - 2 8.5 28.4 0.46 10.6 5.0 2.1 2 0 0 2 2 2 0 YL1 nuclear protein eIF-3c_N PF05470.12 GBG77042.1 - 4 5.6 9.8 5.3 5.2 9.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 GBG77043.1 - 2.9 6.1 8.8 3.8 5.7 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG77043.1 - 6 4.9 11.7 8.3 4.5 11.7 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG77044.1 - 0.2 11.0 14.0 0.3 10.4 14.0 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG77044.1 - 2.2 6.4 13.8 3.2 5.8 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG77044.1 - 3.8 5.7 10.9 5.4 5.2 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Ago_N_1 PF18351.1 GBG77045.1 - 0.058 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Fungal Argonaute N-terminal domain eIF-3_zeta PF05091.12 GBG77045.1 - 0.82 8.6 7.0 1.6 7.7 7.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.14 GBG77046.1 - 0.0016 16.9 10.5 0.0016 16.8 10.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG77046.1 - 0.069 11.4 15.6 0.075 11.2 15.6 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG77046.1 - 0.26 11.1 5.8 0.36 10.6 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YL1 PF05764.13 GBG77046.1 - 0.32 11.1 19.5 0.44 10.6 19.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Mpp10 PF04006.12 GBG77046.1 - 0.42 9.0 16.3 0.51 8.7 16.3 1.1 1 0 0 1 1 1 0 Mpp10 protein CCDC106 PF15794.5 GBG77046.1 - 0.6 9.8 4.7 0.84 9.3 4.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 BUD22 PF09073.10 GBG77046.1 - 0.88 8.8 18.1 1.1 8.5 18.1 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG77046.1 - 1.1 8.6 18.4 1.2 8.5 18.4 1.1 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.11 GBG77046.1 - 1.1 8.6 15.0 1.4 8.3 15.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 GBG77046.1 - 1.3 8.9 19.8 1.8 8.5 19.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Lin-8 PF03353.15 GBG77046.1 - 1.4 8.4 7.3 1.7 8.1 7.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LAP1C PF05609.12 GBG77046.1 - 2.7 7.0 6.2 3.1 6.8 6.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 GBG77046.1 - 4.7 6.0 6.2 5.1 5.8 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HGTP_anticodon2 PF12745.7 GBG77046.1 - 6.9 6.1 6.5 9.2 5.7 6.5 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Presenilin PF01080.17 GBG77046.1 - 8.4 5.0 7.8 9.1 4.9 7.8 1.1 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG77047.1 - 1e-09 38.3 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG77047.1 - 0.096 12.8 1.6 0.17 12.0 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG77048.1 - 1.5e-10 41.0 0.1 3.2e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG77048.1 - 2.3e-07 31.3 0.0 5.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77048.1 - 1.9e-05 25.2 0.0 4.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG77048.1 - 0.027 14.3 0.5 0.052 13.3 0.5 1.4 1 0 0 1 1 1 0 Aspartyl protease Cytochrom_C_2 PF01322.20 GBG77048.1 - 0.24 12.3 3.6 2.5 9.0 0.4 3.4 3 0 0 3 3 3 0 Cytochrome C' Myb_DNA-binding PF00249.31 GBG77049.1 - 1.3 9.3 3.8 0.33 11.2 0.2 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain zf-RING-like PF08746.11 GBG77049.1 - 1.4 9.3 4.3 4.3 7.7 4.3 1.8 1 0 0 1 1 1 0 RING-like domain DDE_Tnp_4 PF13359.6 GBG77050.1 - 9.7e-26 90.3 0.0 2.3e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77050.1 - 1.3e-13 51.1 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77050.1 - 0.00031 20.5 2.6 0.0013 18.4 0.0 2.6 3 0 0 3 3 3 1 Transposase DDE domain Defensin_2 PF01097.18 GBG77050.1 - 3.8 7.5 5.8 20 5.2 1.4 2.9 2 0 0 2 2 2 0 Arthropod defensin DDE_Tnp_4 PF13359.6 GBG77051.1 - 2.1e-14 53.5 0.2 4.5e-13 49.2 0.0 2.9 3 1 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77051.1 - 1.5e-06 28.0 0.0 2.1e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG77051.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG77053.1 - 3.5e-06 27.3 2.0 5.4e-06 26.7 2.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Dimer_Tnp_hAT PF05699.14 GBG77054.1 - 6.1e-05 22.7 1.2 0.00014 21.6 0.2 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 GBG77054.1 - 0.002 18.1 0.3 0.0046 16.9 0.3 1.7 1 0 0 1 1 1 1 BED zinc finger API5 PF05918.11 GBG77054.1 - 0.017 13.9 1.1 0.03 13.1 1.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RVT_1 PF00078.27 GBG77055.1 - 5.3e-21 75.1 0.1 1.2e-20 74.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG77055.1 - 6.5e-12 45.2 0.3 1.9e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Branch PF02485.21 GBG77056.1 - 2.2e-68 230.4 0.0 3.3e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Pro_isomerase PF00160.21 GBG77058.1 - 6.2e-45 153.3 0.7 6.2e-45 153.3 0.7 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PPP4R2 PF09184.11 GBG77058.1 - 0.0051 16.4 3.8 0.0051 16.4 3.8 1.6 2 0 0 2 2 2 1 PPP4R2 FAM176 PF14851.6 GBG77058.1 - 0.017 14.8 3.3 0.082 12.6 3.3 1.9 2 0 0 2 2 2 0 FAM176 family MPP6 PF10175.9 GBG77058.1 - 0.03 14.8 7.7 0.058 13.9 7.7 1.5 1 0 0 1 1 1 0 M-phase phosphoprotein 6 NOA36 PF06524.12 GBG77058.1 - 0.13 11.6 7.1 0.16 11.3 7.1 1.1 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 GBG77058.1 - 1.3 8.0 15.7 1.7 7.5 15.7 1.2 1 0 0 1 1 1 0 Paf1 Integrase_H2C2 PF17921.1 GBG77060.1 - 3.3e-13 49.5 0.0 7.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG77060.1 - 0.0035 17.5 0.0 0.0074 16.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG77061.1 - 1.9e-30 105.6 0.0 4.6e-30 104.4 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77061.1 - 1.4e-14 54.2 0.0 2.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77061.1 - 1.3e-06 28.2 0.1 0.011 15.4 0.0 3.3 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG77061.1 - 0.011 16.1 0.1 5.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain hNIFK_binding PF12196.8 GBG77062.1 - 0.89 9.1 0.0 0.89 9.1 0.0 3.2 4 0 0 4 4 4 0 FHA Ki67 binding domain of hNIFK Nop25 PF09805.9 GBG77062.1 - 7.5 7.0 12.6 47 4.4 0.2 2.7 2 1 0 2 2 2 0 Nucleolar protein 12 (25kDa) DDE_Tnp_4 PF13359.6 GBG77063.1 - 1.1e-30 106.4 0.0 2e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77063.1 - 3.4e-17 62.7 0.0 5.7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77063.1 - 9.3e-05 22.2 0.5 0.36 10.5 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG77064.1 - 1.4e-06 28.6 2.2 1.4e-06 28.6 2.2 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77064.1 - 1.9 8.8 4.9 1.3 9.4 1.0 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RT_RNaseH PF17917.1 GBG77065.1 - 9.3e-22 77.3 0.0 2.5e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77065.1 - 1.9e-21 75.9 0.0 4.7e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77065.1 - 6.6e-09 36.0 0.0 2.8e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG77065.1 - 0.0084 16.4 0.7 0.041 14.1 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG77066.1 - 8.4e-25 87.6 0.1 3.6e-24 85.5 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SBP PF03110.14 GBG77068.1 - 4.2e-30 103.9 13.5 8.5e-30 102.9 13.5 1.5 1 0 0 1 1 1 1 SBP domain zf-B_box PF00643.24 GBG77068.1 - 1.5 9.1 9.0 0.046 13.9 2.8 1.7 2 0 0 2 2 2 0 B-box zinc finger ClpS PF02617.17 GBG77069.1 - 1.1e-06 28.3 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Macoilin PF09726.9 GBG77069.1 - 0.027 13.1 5.3 0.034 12.7 5.3 1.1 1 0 0 1 1 1 0 Macoilin family Rad51 PF08423.11 GBG77070.1 - 2.7e-44 151.3 0.0 6.2e-44 150.2 0.0 1.6 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GBG77070.1 - 3.1e-10 39.9 0.0 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 GBG77070.1 - 1.4e-05 24.7 0.5 0.035 13.6 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 GBG77070.1 - 2.6e-05 23.7 0.5 0.00015 21.2 0.5 2.2 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 GBG77070.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF287 PF03384.14 GBG77071.1 - 1.2 9.6 5.3 0.26 11.7 1.2 2.1 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 His_Phos_1 PF00300.22 GBG77072.1 - 3.4e-14 53.0 0.7 3.2e-08 33.5 0.2 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 GBG77073.1 - 1.7e-14 54.0 0.3 4.1e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 GBG77075.1 - 2.4e-15 56.7 0.2 9.9e-09 35.2 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) CDC45 PF02724.14 GBG77076.1 - 2.2e-24 85.8 0.0 2.5e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Toxin_37 PF11415.8 GBG77076.1 - 1.2 9.1 4.1 4.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Antifungal peptide termicin CDC45 PF02724.14 GBG77077.1 - 4.6e-85 286.2 10.8 1.3e-84 284.8 10.8 1.6 1 1 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 GBG77077.1 - 0.0015 18.7 5.5 0.0025 18.0 5.5 1.3 1 0 0 1 1 1 1 YL1 nuclear protein NOA36 PF06524.12 GBG77077.1 - 1.1 8.5 11.1 1.9 7.7 11.1 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 GBG77077.1 - 2.7 5.9 3.5 3.6 5.6 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC27 PF09507.10 GBG77077.1 - 3.1 7.1 7.0 4.4 6.6 7.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CENP-B_dimeris PF09026.10 GBG77077.1 - 3.5 8.1 14.5 8.6 6.8 14.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 GBG77077.1 - 4.3 5.3 10.5 5.6 4.9 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi RVT_1 PF00078.27 GBG77079.1 - 9.5e-17 61.2 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG77079.1 - 0.00019 21.0 0.1 0.00039 20.0 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myb_DNA-bind_4 PF13837.6 GBG77080.1 - 1.2e-06 28.8 1.0 3.4e-06 27.4 0.3 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77080.1 - 0.14 12.5 0.2 2.9 8.3 0.1 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Histone PF00125.24 GBG77081.1 - 1.2e-15 58.0 0.1 3e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PARP PF00644.20 GBG77082.1 - 1.3e-14 54.2 0.0 1.3e-13 51.0 0.0 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 GBG77082.1 - 2.8e-12 46.7 0.0 5.9e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 ARTD15 N-terminal domain Exotox-A_cataly PF09009.10 GBG77082.1 - 0.042 13.6 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic DUF659 PF04937.15 GBG77083.1 - 4e-37 127.4 0.0 7.5e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Peptidase_M10_C PF08548.11 GBG77083.1 - 0.06 13.2 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal AT_hook PF02178.19 GBG77083.1 - 9.7 6.5 11.3 0.079 12.9 3.1 2.1 2 0 0 2 2 2 0 AT hook motif zf-CCHC PF00098.23 GBG77085.1 - 0.093 12.9 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Mitofilin PF09731.9 GBG77085.1 - 0.34 9.7 14.6 0.46 9.3 14.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TMEM214 PF10151.9 GBG77085.1 - 1 7.8 6.3 1.3 7.4 6.3 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Connexin PF00029.19 GBG77085.1 - 5.1 6.8 5.5 8.3 6.1 5.5 1.3 1 0 0 1 1 1 0 Connexin Ribosomal_L22 PF00237.19 GBG77086.1 - 3.3e-43 146.1 0.2 4.3e-43 145.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Glyco_hydro_9 PF00759.19 GBG77088.1 - 2.8e-103 346.5 2.4 3.3e-103 346.3 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 HTH_57 PF18679.1 GBG77089.1 - 0.52 10.6 2.7 1.2 9.4 0.6 2.3 3 0 0 3 3 3 0 ThcOx helix turn helix domain RskA PF10099.9 GBG77090.1 - 0.98 9.7 14.3 0.039 14.3 5.4 2.8 3 0 0 3 3 3 0 Anti-sigma-K factor rskA PRA1 PF03208.19 GBG77091.1 - 0.0054 16.4 8.7 0.0067 16.1 8.7 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2615 PF11027.8 GBG77091.1 - 0.012 15.7 2.3 0.012 15.7 2.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) 7tm_1 PF00001.21 GBG77091.1 - 0.021 14.1 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) EphA2_TM PF14575.6 GBG77091.1 - 0.057 14.3 2.1 0.5 11.3 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CytochromB561_N PF09786.9 GBG77091.1 - 0.12 11.4 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF4834 PF16118.5 GBG77091.1 - 0.16 13.0 0.0 1.9 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF973 PF06157.11 GBG77091.1 - 0.28 10.2 5.5 0.33 10.0 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Tmemb_9 PF05434.11 GBG77091.1 - 0.36 10.7 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 1 0 TMEM9 TRAP_alpha PF03896.16 GBG77091.1 - 0.42 9.8 7.1 0.029 13.6 1.2 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.6 GBG77091.1 - 1.4 8.6 4.3 0.52 10.0 0.1 2.1 1 1 1 2 2 2 0 FAM176 family PIG-P PF08510.12 GBG77091.1 - 2.3 8.2 9.6 3.5 7.6 9.6 1.4 1 1 0 1 1 1 0 PIG-P DHHC PF01529.20 GBG77091.1 - 7.3 6.7 15.8 9.1 6.4 15.8 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Spo7 PF03907.13 GBG77091.1 - 9.9 5.6 6.7 13 5.2 6.7 1.1 1 0 0 1 1 1 0 Spo7-like protein RVT_1 PF00078.27 GBG77092.1 - 2.4e-27 95.9 0.0 3.8e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77092.1 - 2.3e-19 69.6 0.2 4.3e-19 68.7 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77092.1 - 5.2e-12 45.7 0.1 1.2e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PfkB PF00294.24 GBG77093.1 - 6.9e-28 97.8 0.0 1.6e-27 96.6 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RVP_2 PF08284.11 GBG77093.1 - 1.3e-09 38.0 0.0 2.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77093.1 - 1e-07 32.5 0.0 2.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77093.1 - 2e-05 25.1 0.0 5.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG77093.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease MOZART1 PF12554.8 GBG77094.1 - 6.4e-25 86.7 0.3 8e-25 86.4 0.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated RNaseH_pPIWI_RE PF13032.6 GBG77094.1 - 0.069 13.0 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE RVT_1 PF00078.27 GBG77095.1 - 9.3e-28 97.3 0.0 1.4e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77095.1 - 6.2e-21 74.3 0.0 1.4e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG77095.1 - 7.7e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG77095.1 - 1.3e-10 41.4 0.0 2.8e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG77095.1 - 7.4e-08 32.9 0.0 1.8e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77095.1 - 3.2e-06 27.6 0.0 6.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77095.1 - 0.0036 17.1 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG77095.1 - 0.013 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 RVP PF00077.20 GBG77095.1 - 0.031 14.6 0.0 0.096 13.0 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease KRTAP PF11759.8 GBG77096.1 - 0.69 10.5 30.0 1.9 9.1 30.0 1.7 1 1 0 1 1 1 0 Keratin-associated matrix DUF4253 PF14062.6 GBG77097.1 - 0.0086 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4253) DUF3720 PF12517.8 GBG77097.1 - 0.18 12.8 0.0 0.33 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) RVT_1 PF00078.27 GBG77098.1 - 9e-31 107.1 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77098.1 - 3.1e-16 59.2 0.0 6.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77098.1 - 4.2e-05 23.8 0.0 8.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77099.1 - 7.9e-31 107.3 0.0 1.2e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77099.1 - 2.7e-16 59.4 0.0 6e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77099.1 - 3.7e-05 23.9 0.0 7.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77101.1 - 7.8e-30 102.9 0.0 3.6e-29 100.7 0.0 2.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77101.1 - 1.7e-22 80.0 0.0 1.7e-22 80.0 0.0 2.7 2 2 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77101.1 - 6.6e-19 68.1 0.0 6.6e-19 68.1 0.0 2.4 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase DUF5582 PF17819.1 GBG77102.1 - 0.025 15.0 0.2 0.047 14.2 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5582) DUF349 PF03993.12 GBG77102.1 - 0.084 13.2 5.0 0.17 12.2 2.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) PAP_central PF04928.17 GBG77102.1 - 0.48 9.3 2.1 1.9 7.4 3.2 1.3 1 1 0 1 1 1 0 Poly(A) polymerase central domain rve PF00665.26 GBG77103.1 - 9.9e-10 38.6 0.0 2.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.20 GBG77103.1 - 0.038 14.3 0.1 0.082 13.2 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG77103.1 - 0.039 14.5 0.0 0.097 13.2 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease gag-asp_proteas PF13975.6 GBG77104.1 - 1.7e-07 31.7 0.1 5.5e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77104.1 - 0.00056 20.5 0.0 0.0019 18.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG77104.1 - 0.002 17.9 0.3 0.0034 17.2 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG77104.1 - 0.035 14.4 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease NOP19 PF10863.8 GBG77104.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Nucleolar protein 19 Toprim_N PF08275.11 GBG77105.1 - 7.6e-05 22.8 14.2 55 3.8 0.0 9.9 4 2 8 12 12 12 1 DNA primase catalytic core, N-terminal domain RTA1 PF04479.13 GBG77105.1 - 0.00066 19.3 21.9 52 3.3 0.0 10.7 4 2 8 12 12 12 1 RTA1 like protein PapC_C PF13953.6 GBG77105.1 - 2.1 8.2 41.3 10 6.0 0.7 9.8 3 3 8 11 11 11 0 PapC C-terminal domain RT_RNaseH_2 PF17919.1 GBG77106.1 - 3.3e-29 100.8 0.0 1.1e-28 99.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77106.1 - 1.3e-27 96.8 0.2 1.5e-24 86.8 0.2 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77106.1 - 1.7e-24 86.1 0.0 3.3e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77107.1 - 2.8e-13 49.7 0.0 5.8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77107.1 - 2.8e-11 43.6 0.0 5.7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG77107.1 - 6.7e-05 23.4 0.3 0.00033 21.1 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77107.1 - 0.0031 18.1 0.0 0.0089 16.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG77107.1 - 0.0034 17.2 0.1 0.01 15.7 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG77107.1 - 0.005 17.1 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 GBG77107.1 - 0.077 12.8 0.1 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH PF17917.1 GBG77108.1 - 1.2e-24 86.6 0.1 2.3e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77108.1 - 7.8e-18 64.4 0.1 1.8e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77109.1 - 7.5e-36 123.7 0.6 5.3e-27 94.8 0.2 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77109.1 - 8.5e-30 102.8 0.0 2.1e-19 69.4 0.0 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77109.1 - 3.3e-15 56.2 0.0 2e-14 53.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase UPF0242 PF06785.11 GBG77109.1 - 0.022 14.9 10.8 0.07 13.2 10.8 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4399 PF14347.6 GBG77109.1 - 0.024 15.0 0.0 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) RT_RNaseH_2 PF17919.1 GBG77110.1 - 3.6e-31 107.2 0.0 6.8e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77110.1 - 2.1e-26 92.2 0.1 4.5e-26 91.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77110.1 - 3.8e-18 65.4 0.2 8.1e-18 64.3 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77110.1 - 1.5e-05 25.1 0.0 3.5e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG77110.1 - 0.0003 21.0 0.0 0.00096 19.3 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG77111.1 - 5.1e-32 109.9 0.1 9.9e-32 109.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77111.1 - 4e-28 97.8 0.3 7.6e-28 96.9 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77111.1 - 3.9e-17 62.5 0.0 6.6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77111.1 - 5.5e-17 61.6 0.2 1.2e-16 60.5 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77111.1 - 2.5e-13 50.2 0.0 7.9e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG77111.1 - 0.0049 17.1 0.1 0.0049 17.1 0.1 1.9 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 GBG77112.1 - 2.4e-31 109.0 0.0 4.8e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77112.1 - 1.5e-26 92.3 0.0 4.3e-26 90.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77112.1 - 3.7e-26 91.5 0.0 9.7e-26 90.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77112.1 - 8.9e-17 61.0 0.3 2e-16 59.8 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77112.1 - 1.7e-12 47.6 0.0 4.7e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG77112.1 - 0.0069 16.6 0.1 0.023 14.9 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG77113.1 - 7.8e-28 97.5 3.4 3.1e-27 95.5 0.2 2.8 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77113.1 - 1.2e-17 63.8 0.1 2.5e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG77113.1 - 6.3e-13 48.9 0.2 2.3e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77113.1 - 1.2e-09 38.4 0.1 5.2e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG77113.1 - 5.3e-07 29.6 0.1 0.00066 19.7 0.1 2.9 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG77113.1 - 0.081 13.2 0.0 0.38 11.0 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein ATP_bind_3 PF01171.20 GBG77114.1 - 5.7e-43 146.8 0.0 1e-42 146.0 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RT_RNaseH_2 PF17919.1 GBG77114.1 - 2.7e-31 107.6 0.0 4.6e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77114.1 - 2.3e-29 101.7 0.1 5.2e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SWIRM PF04433.17 GBG77115.1 - 3.7e-29 100.9 0.1 6.3e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 GBG77115.1 - 2.1e-28 98.1 11.2 5.1e-28 96.9 11.2 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 GBG77115.1 - 3.2e-11 43.2 0.1 6.4e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 GBG77115.1 - 1.1e-08 34.8 6.2 1.9e-08 34.0 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 GBG77115.1 - 2.6e-06 27.6 0.0 5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain HHH_4 PF14490.6 GBG77115.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain C1_2 PF03107.16 GBG77115.1 - 0.048 14.0 7.8 0.081 13.3 7.8 1.3 1 0 0 1 1 1 0 C1 domain Zn-ribbon_8 PF09723.10 GBG77115.1 - 7.2 6.8 7.0 15 5.8 7.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain RVT_1 PF00078.27 GBG77116.1 - 0.00013 21.6 0.0 0.0013 18.3 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2362 PF10154.9 GBG77116.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DUF3110 PF11360.8 GBG77117.1 - 3.1e-06 27.3 0.0 9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) RT_RNaseH_2 PF17919.1 GBG77118.1 - 2.7e-30 104.3 0.0 8.4e-30 102.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77118.1 - 3.3e-30 104.5 0.3 8.5e-30 103.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77118.1 - 0.038 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_UL25 PF01499.16 GBG77118.1 - 2.6 6.5 7.4 5.7 5.3 7.4 1.5 1 0 0 1 1 1 0 Herpesvirus UL25 family Pkinase_Tyr PF07714.17 GBG77119.1 - 6.5e-42 143.6 0.0 1e-41 143.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77119.1 - 2.7e-40 138.4 0.0 3.8e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Malectin_like PF12819.7 GBG77119.1 - 4.9e-27 95.0 0.0 4.6e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Malectin-like domain Malectin PF11721.8 GBG77119.1 - 4.6e-17 62.6 0.0 6e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Malectin domain LRR_8 PF13855.6 GBG77119.1 - 9e-08 31.8 2.4 1.9e-07 30.8 2.4 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRRNT_2 PF08263.12 GBG77119.1 - 0.0049 17.2 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 GBG77119.1 - 0.025 15.0 0.7 0.14 12.6 0.2 2.3 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Gram_pos_anchor PF00746.21 GBG77119.1 - 0.079 12.9 0.5 0.17 11.9 0.5 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif APH PF01636.23 GBG77119.1 - 0.091 12.7 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 GBG77119.1 - 0.097 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family LRR_1 PF00560.33 GBG77119.1 - 0.24 12.1 1.3 70 4.6 0.1 3.8 4 0 0 4 4 2 0 Leucine Rich Repeat Exo_endo_phos PF03372.23 GBG77120.1 - 5.2e-07 29.4 0.2 5.2e-07 29.4 0.2 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF724 PF05266.14 GBG77120.1 - 0.17 11.7 2.7 0.27 11.0 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) KH_8 PF17903.1 GBG77121.1 - 2.4e-31 107.7 0.1 2.4e-31 107.7 0.1 2.0 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 GBG77121.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 KH domain DUF5521 PF17659.1 GBG77121.1 - 0.055 11.3 0.3 0.1 10.4 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5521) RVT_1 PF00078.27 GBG77122.1 - 1.4e-16 60.7 0.0 2.5e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG77122.1 - 2.5e-06 27.2 1.4 9.2e-06 25.3 1.4 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HK_sensor PF16750.5 GBG77122.1 - 0.1 12.9 1.3 0.26 11.6 1.3 1.7 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase zf-BED PF02892.15 GBG77123.1 - 6.6e-09 35.7 10.2 0.0076 16.3 0.6 3.5 3 0 0 3 3 3 3 BED zinc finger PyrI_C PF02748.15 GBG77123.1 - 2e-05 24.4 2.6 0.9 9.5 0.0 3.5 3 0 0 3 3 3 3 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_ribbon_SprT PF17283.2 GBG77123.1 - 0.00033 20.5 5.1 1.8 8.5 0.3 3.4 3 0 0 3 3 3 3 SprT-like zinc ribbon domain zf-Sec23_Sec24 PF04810.15 GBG77123.1 - 0.0015 18.6 8.7 2.5 8.2 0.3 3.5 3 0 0 3 3 3 3 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 GBG77123.1 - 0.0045 17.3 5.3 7.9 6.9 0.1 3.5 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-HC5HC2H_2 PF13832.6 GBG77123.1 - 0.01 16.0 6.0 1.5 9.0 0.1 3.0 3 0 0 3 3 3 0 PHD-zinc-finger like domain Ribosomal_L37ae PF01780.19 GBG77123.1 - 0.026 14.6 4.2 16 5.7 0.2 3.4 3 0 0 3 3 3 0 Ribosomal L37ae protein family DUF866 PF05907.13 GBG77123.1 - 0.044 13.7 10.9 1.7 8.6 0.7 3.2 2 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF866) Rep_fac-A_C PF08646.10 GBG77123.1 - 0.052 13.3 3.9 18 5.0 0.2 3.4 3 0 0 3 3 3 0 Replication factor-A C terminal domain Elf1 PF05129.13 GBG77123.1 - 0.23 11.5 4.6 26 4.9 0.1 3.4 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.6 GBG77123.1 - 0.26 12.2 7.3 32 5.7 0.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 GBG77123.1 - 2.1 8.9 5.3 69 4.0 0.0 4.0 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE_2 PF02318.16 GBG77123.1 - 4.9 7.4 10.4 5.5 7.2 0.3 3.6 4 0 0 4 4 4 0 FYVE-type zinc finger zf-HC5HC2H PF13771.6 GBG77123.1 - 6.3 7.1 12.7 5.6 7.3 0.8 3.3 4 0 0 4 4 3 0 PHD-like zinc-binding domain JAB PF01398.21 GBG77124.1 - 2.4e-13 50.1 0.0 4.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Rhabdo_M2 PF04785.12 GBG77125.1 - 0.12 11.6 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Rhabdovirus matrix protein M2 Myb_DNA-bind_4 PF13837.6 GBG77126.1 - 1.2e-08 35.2 0.0 2.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain ALG3 PF05208.13 GBG77128.1 - 2.9e-142 474.3 15.0 4e-142 473.9 15.0 1.2 1 0 0 1 1 1 1 ALG3 protein Tam41_Mmp37 PF09139.11 GBG77128.1 - 1.8e-71 241.3 0.0 4.7e-71 239.9 0.0 1.6 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial GRP PF07172.11 GBG77128.1 - 1.3 9.8 32.1 3.6 8.3 28.2 3.3 2 0 0 2 2 2 0 Glycine rich protein family PLAC8 PF04749.17 GBG77129.1 - 5.3e-23 81.9 11.9 6.9e-23 81.5 11.9 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 GBG77130.1 - 4.7e-25 88.5 7.7 5.9e-25 88.1 7.7 1.1 1 0 0 1 1 1 1 PLAC8 family Orai-1 PF07856.12 GBG77131.1 - 8.8e-28 97.1 0.7 2.5e-27 95.6 0.7 1.7 1 1 0 1 1 1 1 Mediator of CRAC channel activity DUF2207 PF09972.9 GBG77131.1 - 0.14 10.9 5.4 1.7 7.3 5.8 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 GBG77131.1 - 0.85 9.3 4.9 0.28 10.9 1.4 1.8 2 0 0 2 2 2 0 Tetraspanin family RVT_1 PF00078.27 GBG77132.1 - 4.9e-26 91.6 0.1 7.2e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77132.1 - 2.6e-15 56.3 0.0 1.2e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77132.1 - 7.3e-06 26.2 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG77132.1 - 0.00012 22.6 0.0 0.00024 21.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77132.1 - 0.00016 22.3 0.0 0.00036 21.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG77132.1 - 0.00029 20.6 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG77132.1 - 0.002 17.9 0.0 0.0052 16.6 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Phage_lysozyme PF00959.19 GBG77133.1 - 0.017 15.5 0.7 0.55 10.7 0.1 2.4 2 0 0 2 2 2 0 Phage lysozyme TssO PF17561.2 GBG77133.1 - 0.56 10.3 3.8 0.31 11.1 1.4 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssO CDC45 PF02724.14 GBG77134.1 - 0.94 7.7 4.4 1.1 7.5 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG77134.1 - 1.2 7.2 5.7 1.2 7.3 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG77135.1 - 4.6e-25 87.6 0.0 1.8e-24 85.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77135.1 - 4.9e-23 81.4 0.0 1.6e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77135.1 - 2.5e-17 62.7 0.3 5.8e-17 61.5 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Cupin_1 PF00190.22 GBG77135.1 - 3.3e-15 56.0 0.2 1.1e-12 47.8 0.2 2.6 2 0 0 2 2 2 2 Cupin Asp_protease_2 PF13650.6 GBG77135.1 - 1.8e-07 31.7 0.0 4.2e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77135.1 - 1.8e-06 28.4 0.0 4.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77135.1 - 2.2e-06 27.5 0.0 4.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG77135.1 - 0.0005 20.3 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG77135.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG77135.1 - 0.053 13.7 0.2 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger NUDIX PF00293.28 GBG77136.1 - 1e-10 41.8 0.8 1.7e-10 41.0 0.8 1.3 1 0 0 1 1 1 1 NUDIX domain THUMP PF02926.17 GBG77139.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 THUMP domain DUF659 PF04937.15 GBG77140.1 - 7.6e-27 94.0 0.0 1.1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG77140.1 - 6.9e-05 22.6 0.0 0.00018 21.2 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SGP PF17228.2 GBG77140.1 - 1 10.3 4.2 3.1 8.7 4.2 1.8 1 0 0 1 1 1 0 Sulphur globule protein RVT_1 PF00078.27 GBG77141.1 - 7.2e-36 123.8 0.1 1.4e-35 122.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77141.1 - 1.4e-28 99.3 0.3 1.3e-27 96.1 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77141.1 - 3.7e-28 97.5 0.1 2.5e-27 94.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77141.1 - 7.7e-18 64.8 0.0 2.6e-17 63.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG77141.1 - 4e-15 55.7 1.9 8.6e-15 54.6 1.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG77141.1 - 0.085 12.8 1.4 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_M24 PF00557.24 GBG77142.1 - 4.6e-57 193.1 0.1 1e-56 191.9 0.1 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 RVT_1 PF00078.27 GBG77142.1 - 2.4e-24 86.1 0.1 5.9e-24 84.8 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77142.1 - 2.7e-11 43.4 0.0 8e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77142.1 - 0.0068 16.7 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Usp PF00582.26 GBG77144.1 - 2.9e-30 105.6 0.6 5.3e-29 101.5 0.6 2.0 1 1 0 1 1 1 1 Universal stress protein family RT_RNaseH_2 PF17919.1 GBG77147.1 - 2.9e-25 88.2 0.0 9.9e-25 86.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77147.1 - 2.9e-24 85.3 0.0 6.2e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77147.1 - 1.3e-09 38.2 0.0 5.3e-09 36.3 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG77147.1 - 5.8e-07 29.5 2.3 1.2e-06 28.5 2.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG77147.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG77148.1 - 4.1e-19 69.0 0.0 7.6e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tudor-knot PF11717.8 GBG77148.1 - 2.4e-05 24.1 0.5 0.0001 22.1 0.0 2.3 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG77148.1 - 0.008 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Spc29 PF17082.5 GBG77148.1 - 0.075 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 SlyX PF04102.12 GBG77148.1 - 2.6 8.7 12.2 0.17 12.6 4.5 3.0 2 1 1 3 3 3 0 SlyX Myb_DNA-bind_4 PF13837.6 GBG77150.1 - 1e-06 29.0 0.7 1e-06 29.0 0.7 2.8 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG77150.1 - 3e-05 23.9 2.4 7.9e-05 22.6 2.4 1.8 1 0 0 1 1 1 1 Zinc knuckle Borrelia_P83 PF05262.11 GBG77150.1 - 1.8 7.0 15.6 2.6 6.5 15.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2058 PF09831.9 GBG77150.1 - 2.7 8.1 14.6 9.4 6.3 14.6 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) CorA PF01544.18 GBG77151.1 - 0.007 15.7 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SlyX PF04102.12 GBG77151.1 - 0.021 15.4 4.4 0.025 15.2 1.1 2.5 1 1 1 2 2 2 0 SlyX YscO PF07321.12 GBG77151.1 - 0.057 13.4 0.6 0.088 12.8 0.6 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO DUF2730 PF10805.8 GBG77151.1 - 0.069 13.2 0.1 0.37 10.9 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) HrpB7 PF09486.10 GBG77151.1 - 0.093 13.1 4.1 0.18 12.2 4.1 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) TolA_bind_tri PF16331.5 GBG77151.1 - 0.36 10.9 4.9 0.39 10.8 3.0 1.9 1 1 1 2 2 2 0 TolA binding protein trimerisation Cnn_1N PF07989.11 GBG77151.1 - 0.54 10.5 2.6 12 6.1 0.3 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 RT_RNaseH_2 PF17919.1 GBG77152.1 - 3e-30 104.2 0.2 8.9e-30 102.7 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77152.1 - 3.2e-30 104.5 0.2 1.5e-29 102.4 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF454 PF04304.13 GBG77152.1 - 0.18 11.8 0.4 19 5.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF454) CdvA PF18822.1 GBG77152.1 - 1.8 8.4 8.2 24 4.8 0.1 3.3 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Methyltransf_1N PF02870.15 GBG77153.1 - 0.0015 19.3 14.2 11 6.9 0.0 7.9 1 1 9 10 10 10 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain PapC_C PF13953.6 GBG77153.1 - 0.0026 17.5 42.6 6.4 6.7 0.2 10.5 1 1 12 13 13 13 8 PapC C-terminal domain RTA1 PF04479.13 GBG77153.1 - 0.021 14.4 13.4 49 3.4 0.0 8.0 4 3 7 11 11 11 0 RTA1 like protein SH3_19 PF18597.1 GBG77153.1 - 4.1 7.3 41.2 23 4.9 0.2 10.6 12 0 0 12 12 12 0 Myosin X N-terminal SH3 domain DdrB PF12747.7 GBG77153.1 - 7.9 6.3 22.3 59 3.5 0.5 6.7 1 1 7 8 8 8 0 DdrB-like protein DUF2358 PF10184.9 GBG77154.1 - 2.3e-12 47.2 0.0 3.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 GBG77154.1 - 6.6e-05 23.5 0.0 0.00015 22.3 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain CytB6-F_Fe-S PF08802.10 GBG77154.1 - 0.35 10.9 1.6 0.79 9.8 1.6 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit DUF2358 PF10184.9 GBG77155.1 - 2.8e-13 50.1 0.0 4.4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 GBG77155.1 - 0.0011 19.5 0.1 0.002 18.7 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain W2 PF02020.18 GBG77156.1 - 1.1e-17 63.9 0.1 1.1e-17 63.9 0.1 3.8 3 0 0 3 3 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 GBG77156.1 - 4e-12 45.3 18.8 0.00028 20.5 3.3 3.7 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GBG77156.1 - 0.032 13.2 0.1 0.05 12.5 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase RNase_H2_suC PF08615.11 GBG77156.1 - 0.047 13.9 0.2 0.9 9.7 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) NTP_transferase PF00483.23 GBG77156.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase DUF4954 PF16314.5 GBG77156.1 - 0.14 10.2 2.5 0.28 9.2 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) Sigma70_ner PF04546.13 GBG77156.1 - 0.45 10.4 12.5 0.27 11.1 4.6 3.0 3 0 0 3 3 3 0 Sigma-70, non-essential region Hexapep_2 PF14602.6 GBG77156.1 - 1.1 9.1 12.6 3.4 7.5 2.3 3.8 3 2 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase RXT2_N PF08595.11 GBG77156.1 - 1.3 9.1 10.9 11 6.0 0.2 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 GBG77156.1 - 3.9 7.2 15.7 1.1 9.0 6.6 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.11 GBG77156.1 - 4.7 5.2 11.4 2.4 6.1 0.1 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Spore_III_AF PF09581.10 GBG77156.1 - 5.5 7.0 8.7 31 4.5 5.1 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) NAD_binding_10 PF13460.6 GBG77158.1 - 1.5e-15 57.5 0.2 3.4e-15 56.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GBG77158.1 - 2.3e-09 37.1 0.4 3.7e-09 36.5 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 GBG77158.1 - 2e-07 30.3 0.1 2.9e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GBG77158.1 - 3.5e-06 26.6 0.1 6.1e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family gag-asp_proteas PF13975.6 GBG77158.1 - 0.0011 19.5 0.0 0.0024 18.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77158.1 - 0.0037 17.0 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Polysacc_synt_2 PF02719.15 GBG77158.1 - 0.023 13.8 0.3 0.11 11.6 0.3 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Asp_protease_2 PF13650.6 GBG77158.1 - 0.042 14.5 0.0 0.13 13.0 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease NAD_binding_4 PF07993.12 GBG77158.1 - 0.046 12.9 1.1 0.48 9.6 1.1 2.2 1 1 0 1 1 1 0 Male sterility protein DUF1758 PF05585.12 GBG77158.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) GDP_Man_Dehyd PF16363.5 GBG77158.1 - 0.068 12.6 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 GBG77158.1 - 0.17 11.4 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF3640 PF12342.8 GBG77158.1 - 0.36 10.6 1.8 0.86 9.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) DUF4360 PF14273.6 GBG77159.1 - 1.4e-22 80.4 1.5 1.7e-22 80.2 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DIM PF08194.12 GBG77159.1 - 0.11 12.7 1.9 0.31 11.3 1.9 1.7 1 0 0 1 1 1 0 DIM protein Myb_DNA-bind_4 PF13837.6 GBG77161.1 - 9.3e-07 29.2 2.4 1.5e-06 28.5 2.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77161.1 - 0.37 11.2 1.8 0.46 10.8 0.6 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2730 PF10805.8 GBG77162.1 - 0.011 15.8 0.4 0.2 11.8 0.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) CENP-X PF09415.10 GBG77162.1 - 6.7 7.1 13.2 0.52 10.7 1.9 2.9 2 1 0 2 2 2 0 CENP-S associating Centromere protein X Integrase_H2C2 PF17921.1 GBG77163.1 - 1.7e-18 66.5 2.4 3.6e-18 65.4 0.5 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG77163.1 - 2.6e-08 34.1 0.0 9.9e-08 32.2 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG77163.1 - 3.6e-05 24.3 0.0 9.4e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77163.1 - 4.2e-05 24.0 0.0 0.00015 22.3 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77163.1 - 0.0019 18.0 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG77163.1 - 0.0039 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG77163.1 - 0.0091 16.2 7.1 0.013 15.8 0.0 4.0 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG77163.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG77164.1 - 1.7e-18 66.5 2.4 3.6e-18 65.4 0.5 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG77164.1 - 2.6e-08 34.1 0.0 9.9e-08 32.2 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG77164.1 - 3.6e-05 24.3 0.0 9.4e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77164.1 - 4.2e-05 24.0 0.0 0.00015 22.3 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77164.1 - 0.0019 18.0 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG77164.1 - 0.0039 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG77164.1 - 0.0091 16.2 7.1 0.013 15.8 0.0 4.0 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG77164.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG77165.1 - 0.00087 19.3 0.8 0.0023 17.9 0.8 1.8 1 0 0 1 1 1 1 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG77166.1 - 0.00052 20.4 3.7 0.00052 20.4 3.7 1.9 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain ETRAMP PF09716.10 GBG77168.1 - 0.45 10.6 8.4 7.3 6.7 0.2 3.0 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RT_RNaseH_2 PF17919.1 GBG77169.1 - 2e-22 79.1 0.0 4.8e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77169.1 - 5.1e-21 74.9 0.0 9e-20 70.9 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG77169.1 - 0.025 14.9 0.2 0.13 12.6 0.1 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein EXS PF03124.14 GBG77174.1 - 3.8e-80 269.7 25.4 5.5e-80 269.2 25.4 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GBG77174.1 - 3.6e-35 122.6 30.8 4.5e-17 63.1 0.0 4.3 4 1 0 4 4 4 3 SPX domain rve PF00665.26 GBG77174.1 - 5.8e-15 55.5 0.0 1.3e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Tmemb_14 PF03647.13 GBG77174.1 - 0.062 14.0 0.1 0.062 14.0 0.1 2.3 2 0 0 2 2 2 0 Transmembrane proteins 14C rve_3 PF13683.6 GBG77174.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain LapA_dom PF06305.11 GBG77174.1 - 4.1 7.3 4.9 18 5.3 0.4 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Retrotrans_gag PF03732.17 GBG77175.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein LAGLIDADG_1 PF00961.19 GBG77176.1 - 0.33 11.9 4.2 0.41 11.6 4.2 1.1 1 0 0 1 1 1 0 LAGLIDADG endonuclease WD40 PF00400.32 GBG77177.1 - 1.3e-23 82.8 15.7 2.6e-05 24.9 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF2951 PF11166.8 GBG77178.1 - 0.036 14.3 2.1 0.036 14.3 2.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) TMF_TATA_bd PF12325.8 GBG77178.1 - 0.063 13.5 0.4 0.063 13.5 0.4 5.1 2 2 2 5 5 5 0 TATA element modulatory factor 1 TATA binding DUF3216 PF11505.8 GBG77178.1 - 0.15 12.3 5.5 0.052 13.8 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) NPV_P10 PF05531.12 GBG77178.1 - 0.5 10.9 10.0 7.5 7.1 0.6 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3573 PF12097.8 GBG77178.1 - 1.3 7.8 2.4 1.4 7.7 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) CENP-F_leu_zip PF10473.9 GBG77178.1 - 1.4 8.9 47.7 0.35 10.9 9.0 4.5 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 GBG77178.1 - 2.2 8.5 49.6 1.1 9.4 12.3 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF3037 PF11236.8 GBG77178.1 - 2.9 8.3 13.7 1.2 9.6 1.1 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF3037) Fib_alpha PF08702.10 GBG77178.1 - 3.8 7.7 28.0 0.51 10.5 11.8 3.9 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family Rootletin PF15035.6 GBG77178.1 - 4.4 7.3 43.4 1.3 9.0 19.7 3.7 2 2 2 4 4 4 0 Ciliary rootlet component, centrosome cohesion GAS PF13851.6 GBG77178.1 - 6.1 6.1 45.9 2.6 7.4 18.7 3.7 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding GAS PF13851.6 GBG77179.1 - 0.00048 19.5 9.0 0.00048 19.5 9.0 2.9 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Tup_N PF08581.10 GBG77179.1 - 0.0056 16.9 9.8 0.0056 16.9 9.8 2.9 2 1 0 3 3 3 1 Tup N-terminal DUF4250 PF14056.6 GBG77179.1 - 0.38 10.7 2.1 5.9 6.9 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Atg14 PF10186.9 GBG77179.1 - 0.63 9.1 32.9 1.1 8.3 9.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.6 GBG77179.1 - 1.2 8.7 39.3 1.8 8.2 39.3 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF812 PF05667.11 GBG77179.1 - 1.7 7.5 32.4 3.3 6.5 32.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 GBG77179.1 - 2.2 7.7 39.0 4.9 6.5 12.6 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 GBG77179.1 - 3.1 6.6 37.8 3 6.6 17.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 GBG77179.1 - 4.1 7.5 34.4 0.062 13.4 13.6 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 GBG77179.1 - 5.3 7.1 40.4 0.048 13.7 11.4 2.7 1 1 1 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 GBG77179.1 - 5.8 6.7 29.8 0.24 11.2 5.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 GBG77179.1 - 7.1 6.7 19.9 0.16 12.0 4.3 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 GBG77179.1 - 9.5 6.6 36.2 9.1 6.7 24.3 2.4 1 1 1 2 2 2 0 Fez1 TPT PF03151.16 GBG77180.1 - 4.2e-08 32.9 4.3 5.7e-08 32.4 4.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG77180.1 - 0.21 11.8 22.2 0.052 13.7 6.3 2.5 2 0 0 2 2 2 0 EamA-like transporter family Cob_adeno_trans PF01923.18 GBG77181.1 - 0.18 11.9 12.3 0.056 13.6 7.3 2.4 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF1664 PF07889.12 GBG77181.1 - 0.71 9.9 16.1 1.5 8.9 7.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) H-kinase_dim PF02895.14 GBG77181.1 - 2.9 8.3 9.8 9.6 6.7 0.1 3.4 2 1 1 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF2730 PF10805.8 GBG77181.1 - 4.8 7.3 12.0 2.1 8.5 6.2 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) NPV_P10 PF05531.12 GBG77181.1 - 6.9 7.2 11.5 5 7.7 0.7 3.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 GBG77182.1 - 0.24 11.7 12.6 14 6.0 2.1 4.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 GBG77182.1 - 0.67 10.0 11.9 2.6 8.1 3.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 GBG77182.1 - 0.71 10.4 6.3 4.9 7.7 1.0 3.1 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 GBG77182.1 - 0.73 10.0 7.8 0.34 11.0 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Sec34 PF04136.15 GBG77182.1 - 0.94 9.3 14.8 3.1 7.7 2.5 2.8 2 0 0 2 2 2 0 Sec34-like family USP8_interact PF08941.10 GBG77182.1 - 3.1 7.6 14.5 0.44 10.3 1.2 3.0 3 0 0 3 3 3 0 USP8 interacting FlaC_arch PF05377.11 GBG77182.1 - 6.2 7.3 15.7 1.4 9.4 3.8 4.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) FOXP-CC PF16159.5 GBG77182.1 - 9.6 6.9 7.0 5.8 7.6 1.6 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain SOBP PF15279.6 GBG77183.1 - 9.3 6.8 21.1 14 6.2 21.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Lebercilin PF15619.6 GBG77185.1 - 0.0093 15.6 7.6 0.011 15.4 6.0 1.7 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF4164 PF13747.6 GBG77185.1 - 0.011 16.0 7.4 0.023 14.9 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 GBG77185.1 - 0.014 15.9 8.8 0.027 15.0 8.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 GBG77185.1 - 0.015 15.4 2.0 0.023 14.8 2.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DASH_Duo1 PF08651.10 GBG77185.1 - 0.038 13.8 0.1 0.081 12.7 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 CLZ PF16526.5 GBG77185.1 - 0.038 14.3 0.7 0.038 14.3 0.7 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fmp27_WPPW PF10359.9 GBG77185.1 - 0.068 12.0 1.3 0.079 11.8 1.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Laminin_II PF06009.12 GBG77185.1 - 0.071 13.1 3.5 2.3 8.2 0.4 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF3450 PF11932.8 GBG77185.1 - 0.16 11.2 5.4 0.31 10.3 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Rho_Binding PF08912.11 GBG77185.1 - 0.23 12.3 5.0 0.37 11.6 1.1 2.4 1 1 1 2 2 2 0 Rho Binding Syntaxin-6_N PF09177.11 GBG77185.1 - 0.33 11.5 5.1 0.73 10.4 3.9 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DivIC PF04977.15 GBG77185.1 - 0.62 9.9 5.4 1 9.2 3.2 2.4 1 1 2 3 3 3 0 Septum formation initiator RT_RNaseH_2 PF17919.1 GBG77186.1 - 2.7e-27 94.7 0.0 5e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77186.1 - 2.4e-25 88.8 0.0 4.7e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77186.1 - 0.00026 21.0 0.3 0.00064 19.8 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG77188.1 - 1.8e-07 31.6 0.0 4.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77188.1 - 4.6e-05 24.0 0.1 0.00013 22.6 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG77188.1 - 0.00056 19.7 0.1 0.0052 16.6 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG77188.1 - 0.0032 17.8 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4045 PF13254.6 GBG77188.1 - 4.6 6.8 20.3 2.2 7.8 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Thiolase_N PF00108.23 GBG77189.1 - 1.1e-23 83.9 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GBG77190.1 - 1.3e-49 167.0 1.1 1.5e-49 166.7 0.4 1.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 GBG77190.1 - 1e-07 31.6 0.5 1.7e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Thiolase, N-terminal domain ACP_syn_III_C PF08541.10 GBG77190.1 - 0.00056 20.0 0.1 0.0018 18.4 0.0 1.8 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ketoacyl-synt_C PF02801.22 GBG77190.1 - 0.055 13.5 0.1 0.54 10.3 0.0 2.2 1 1 1 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF659 PF04937.15 GBG77191.1 - 7.8e-19 68.0 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Beta_helix PF13229.6 GBG77192.1 - 1.2e-05 25.2 11.2 0.00093 19.1 0.7 2.2 1 1 2 3 3 3 2 Right handed beta helix region NeA_P2 PF12312.8 GBG77193.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Beta_helix PF13229.6 GBG77193.1 - 0.11 12.3 4.9 0.45 10.3 4.9 1.9 1 1 0 1 1 1 0 Right handed beta helix region Chlam_PMP PF02415.17 GBG77193.1 - 0.2 12.2 32.4 3 8.5 0.1 6.9 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Mur_ligase PF01225.25 GBG77193.1 - 4.6 7.6 7.0 25 5.3 0.2 2.3 1 1 1 2 2 2 0 Mur ligase family, catalytic domain zf-TRAF PF02176.18 GBG77195.1 - 1.5e-12 48.0 10.3 6.6e-11 42.7 2.4 2.5 2 0 0 2 2 2 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 GBG77195.1 - 0.05 14.1 11.9 0.41 11.1 5.2 2.3 1 1 1 2 2 2 0 TRAF-like zinc-finger Sina PF03145.16 GBG77195.1 - 3 7.8 10.8 11 6.0 3.0 2.5 1 1 2 3 3 3 0 Seven in absentia protein family DUF815 PF05673.13 GBG77196.1 - 3.6e-34 118.1 0.0 5.6e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 GBG77196.1 - 1.1e-05 25.9 0.0 2.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 GBG77196.1 - 0.00071 18.6 0.3 0.0012 17.8 0.3 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 GBG77196.1 - 0.0014 18.9 0.1 0.0035 17.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 GBG77196.1 - 0.0052 16.9 0.1 0.0088 16.2 0.1 1.2 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_30 PF13604.6 GBG77196.1 - 0.013 15.3 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GBG77196.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 GBG77196.1 - 0.016 15.2 0.3 0.047 13.7 0.2 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 GBG77196.1 - 0.025 14.6 0.1 0.045 13.8 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 GBG77196.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 GBG77196.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 GBG77196.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GBG77196.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4023 PF13215.6 GBG77196.1 - 0.09 12.8 0.9 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) DUF853 PF05872.12 GBG77196.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Kinesin PF00225.23 GBG77196.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain AAA_24 PF13479.6 GBG77196.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 GBG77196.1 - 0.26 11.1 0.0 0.48 10.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein DUF815 PF05673.13 GBG77197.1 - 2.2e-40 138.4 0.0 1.7e-22 79.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF815) AAA_16 PF13191.6 GBG77197.1 - 2.1e-05 24.9 0.7 7.9e-05 23.1 0.7 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 GBG77197.1 - 0.00021 21.5 0.2 0.0096 16.0 0.1 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 GBG77197.1 - 0.00025 21.4 0.3 0.0039 17.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 GBG77197.1 - 0.00084 18.3 1.8 0.0013 17.7 0.3 1.9 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 GBG77197.1 - 0.0051 16.8 0.1 0.049 13.6 0.1 2.1 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 GBG77197.1 - 0.0084 15.8 0.7 0.029 14.1 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GBG77197.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 GBG77197.1 - 0.013 15.5 0.2 0.052 13.5 0.2 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 GBG77197.1 - 0.025 14.6 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 GBG77197.1 - 0.031 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 GBG77197.1 - 0.036 14.1 0.0 9 6.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GBG77197.1 - 0.044 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 GBG77197.1 - 0.088 13.2 0.0 0.22 11.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4023 PF13215.6 GBG77197.1 - 0.11 12.6 0.9 1.9 8.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Kinesin PF00225.23 GBG77197.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain DUF853 PF05872.12 GBG77197.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_24 PF13479.6 GBG77197.1 - 0.21 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 GBG77197.1 - 0.21 10.4 0.1 0.41 9.5 0.1 1.4 1 0 0 1 1 1 0 AFG1-like ATPase AAA_26 PF13500.6 GBG77197.1 - 0.22 11.3 0.0 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 GBG77197.1 - 0.34 10.8 1.2 2.6 7.9 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B HSP70 PF00012.20 GBG77198.1 - 1.1e-19 70.1 0.0 1.3e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF3490 PF11995.8 GBG77199.1 - 0.00068 19.5 0.5 0.0017 18.2 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3490) SUIM_assoc PF16619.5 GBG77199.1 - 5.6 7.1 22.9 13 5.9 3.8 4.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Retrotrans_gag PF03732.17 GBG77200.1 - 0.13 12.6 0.1 0.49 10.7 0.0 1.9 1 1 1 2 2 2 0 Retrotransposon gag protein Myb_DNA-bind_4 PF13837.6 GBG77201.1 - 8.6e-10 38.9 0.8 8.6e-10 38.9 0.8 2.3 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77201.1 - 0.12 12.7 0.3 0.32 11.3 0.3 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like IRK_C PF17655.1 GBG77202.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain DUF810 PF05664.11 GBG77203.1 - 9.1e-182 606.2 0.2 1.3e-181 605.6 0.2 1.2 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) Membr_traf_MHD PF10540.9 GBG77203.1 - 0.013 15.7 0.0 0.057 13.6 0.0 2.2 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain zf-C3HC4_3 PF13920.6 GBG77204.1 - 2.3e-18 65.7 23.2 1.6e-09 37.5 10.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG77204.1 - 2.8e-06 27.1 23.9 0.00059 19.7 4.4 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 PUF PF00806.19 GBG77204.1 - 4.8e-06 26.0 0.0 0.19 11.5 0.0 5.1 5 0 0 5 5 5 1 Pumilio-family RNA binding repeat zf-C3HC4 PF00097.25 GBG77204.1 - 1.9e-05 24.5 5.5 1.9e-05 24.5 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG77204.1 - 4e-05 23.9 5.5 4e-05 23.9 5.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GBG77204.1 - 0.00016 21.6 7.1 0.00016 21.6 7.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG77204.1 - 0.0089 16.0 3.1 0.0089 16.0 3.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 GBG77204.1 - 0.0091 15.8 6.8 0.0091 15.8 6.8 2.7 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain Pellino PF04710.14 GBG77204.1 - 0.3 9.7 1.0 0.54 8.9 1.0 1.3 1 0 0 1 1 1 0 Pellino DUF659 PF04937.15 GBG77205.1 - 2.9e-22 79.2 0.0 4.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG77205.1 - 0.0028 17.4 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF494 PF04361.13 GBG77205.1 - 0.23 11.4 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF494) DRMBL PF07522.14 GBG77206.1 - 3.1e-31 107.8 0.0 5.5e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 GBG77206.1 - 0.008 16.2 1.4 0.026 14.6 0.1 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GBG77206.1 - 0.013 15.0 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain RMMBL PF07521.12 GBG77206.1 - 0.052 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Radial_spoke PF04712.12 GBG77206.1 - 3.4 6.5 23.0 1.6 7.6 12.5 2.6 3 0 0 3 3 3 0 Radial spokehead-like protein CCT PF06203.14 GBG77207.1 - 1.2e-14 54.1 11.6 1.6e-14 53.6 11.6 1.2 1 0 0 1 1 1 1 CCT motif GATA PF00320.27 GBG77207.1 - 6.1e-14 51.3 1.8 1.5e-13 50.0 1.8 1.8 1 0 0 1 1 1 1 GATA zinc finger tify PF06200.14 GBG77207.1 - 6.6e-09 34.9 0.0 1.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 tify domain CCT_2 PF09425.10 GBG77207.1 - 1.3e-05 25.0 3.4 2.3e-05 24.2 3.4 1.4 1 0 0 1 1 1 1 Divergent CCT motif zf-Dof PF02701.15 GBG77207.1 - 0.067 13.4 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger Spt20 PF12090.8 GBG77207.1 - 0.27 10.8 10.4 0.69 9.5 10.4 1.6 1 0 0 1 1 1 0 Spt20 family zf-CCCH PF00642.24 GBG77208.1 - 3e-18 65.2 22.7 7.5e-07 28.9 4.2 3.9 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GBG77208.1 - 0.45 10.4 25.3 0.023 14.5 5.6 3.5 3 0 0 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GBG77208.1 - 0.73 10.0 32.8 0.37 10.9 5.2 4.0 4 0 0 4 4 4 0 Zinc finger domain RT_RNaseH_2 PF17919.1 GBG77209.1 - 3.5e-34 116.8 0.1 6.4e-34 116.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77209.1 - 1e-31 109.3 0.1 1.8e-31 108.5 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77209.1 - 9.6e-15 54.7 0.1 1.4e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PPR PF01535.20 GBG77210.1 - 7.9e-26 88.5 26.5 1.2e-05 25.2 0.4 12.0 13 0 0 13 13 13 8 PPR repeat PPR_2 PF13041.6 GBG77210.1 - 1.4e-22 79.6 10.2 6.9e-06 26.2 0.3 8.2 6 2 3 9 9 9 6 PPR repeat family PPR_1 PF12854.7 GBG77210.1 - 5.8e-17 61.1 0.0 9.7e-05 22.0 0.0 5.9 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 GBG77210.1 - 1.1e-08 34.7 0.0 0.00058 19.3 0.0 3.7 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 GBG77210.1 - 1.1e-07 31.8 0.1 5.7 7.1 0.0 6.1 5 1 1 6 6 6 3 Pentatricopeptide repeat domain TPR_19 PF14559.6 GBG77210.1 - 0.077 13.5 1.0 14 6.2 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Linker_histone PF00538.19 GBG77211.1 - 0.048 14.0 0.5 3.1 8.2 0.1 2.6 1 1 1 2 2 2 0 linker histone H1 and H5 family DUF2868 PF11067.8 GBG77211.1 - 0.58 9.6 4.2 0.74 9.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) PPR_2 PF13041.6 GBG77212.1 - 6.5e-22 77.5 0.2 1.4e-06 28.4 0.0 5.7 3 1 3 6 6 6 5 PPR repeat family PPR_3 PF13812.6 GBG77212.1 - 3.8e-19 68.5 0.1 2.7e-05 24.1 0.0 4.3 3 1 1 4 4 4 4 Pentatricopeptide repeat domain PPR PF01535.20 GBG77212.1 - 2.3e-11 43.1 4.1 0.053 13.8 0.0 5.5 6 0 0 6 6 6 3 PPR repeat PPR_1 PF12854.7 GBG77212.1 - 3.1e-10 39.6 0.0 0.0098 15.6 0.0 5.2 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 GBG77212.1 - 7.1e-10 38.6 0.0 5.8e-06 25.8 0.0 2.5 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 GBG77212.1 - 0.47 9.3 0.0 0.47 9.3 0.0 3.0 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S27 UPF0524 PF15823.5 GBG77212.1 - 7.9 5.8 10.1 18 4.6 10.1 1.6 1 0 0 1 1 1 0 UPF0524 of C3orf70 Aldo_ket_red PF00248.21 GBG77213.1 - 2.5e-54 184.5 0.0 2.8e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HCO3_cotransp PF00955.21 GBG77214.1 - 4.4e-115 385.4 9.4 1.3e-59 202.4 3.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family ZF-HD_dimer PF04770.12 GBG77214.1 - 0.11 12.8 0.3 0.36 11.2 0.3 1.9 1 0 0 1 1 1 0 ZF-HD protein dimerisation region Multi_Drug_Res PF00893.19 GBG77214.1 - 1.5 9.6 6.7 2.4 8.9 0.1 3.4 2 1 2 4 4 4 0 Small Multidrug Resistance protein RT_RNaseH_2 PF17919.1 GBG77215.1 - 5.4e-27 93.7 0.0 2.2e-26 91.8 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77215.1 - 6.8e-21 74.5 0.0 2.4e-20 72.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Noelin-1 PF12308.8 GBG77215.1 - 2.3 8.3 8.5 2.4 8.2 0.6 3.2 2 0 0 2 2 2 0 Neurogenesis glycoprotein FAM199X PF15814.5 GBG77216.1 - 0.27 10.2 10.0 0.47 9.5 10.0 1.3 1 0 0 1 1 1 0 Protein family FAM199X Kinesin PF00225.23 GBG77218.1 - 1.8e-99 332.9 0.0 1.8e-99 332.9 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GBG77218.1 - 2.7e-18 66.4 0.0 7.6e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding RT_RNaseH_2 PF17919.1 GBG77218.1 - 4.3e-16 58.8 0.0 2.6e-15 56.2 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77218.1 - 1.2e-11 44.6 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77218.1 - 4.8e-07 30.0 0.0 2.9e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase LSM PF01423.22 GBG77219.1 - 8.7e-19 67.0 0.1 9.8e-19 66.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GBG77219.1 - 0.00039 20.5 0.0 0.00044 20.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain COBRA PF04833.15 GBG77220.1 - 4.1e-20 72.3 0.3 1.9e-19 70.1 0.3 2.0 1 1 0 1 1 1 1 COBRA-like protein CBM_2 PF00553.19 GBG77220.1 - 0.043 14.1 0.7 1.7 9.0 0.1 3.1 3 0 0 3 3 3 0 Cellulose binding domain RVT_1 PF00078.27 GBG77221.1 - 5e-27 94.9 0.0 7.5e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG77221.1 - 1.4e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77221.1 - 0.0027 18.3 0.0 0.0062 17.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77221.1 - 0.011 16.3 0.0 0.03 14.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease FAM176 PF14851.6 GBG77221.1 - 0.073 12.7 2.1 0.28 10.8 2.1 2.0 1 1 0 1 1 1 0 FAM176 family NOA36 PF06524.12 GBG77221.1 - 0.08 12.3 4.0 0.14 11.5 4.0 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GBG77221.1 - 0.45 8.8 6.4 0.73 8.0 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 GBG77221.1 - 0.48 9.5 0.0 0.48 9.5 0.0 2.3 2 0 0 2 2 2 0 Drosophila roughex protein TFIIA PF03153.13 GBG77221.1 - 2.3 8.1 12.6 0.076 13.0 5.7 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 GBG77221.1 - 2.4 7.5 15.6 5.3 6.4 15.6 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG77221.1 - 5.2 5.1 14.7 8.4 4.5 14.7 1.2 1 0 0 1 1 1 0 Nop14-like family TPR_1 PF00515.28 GBG77222.1 - 1.2e-23 81.9 2.1 3.3e-06 26.7 0.0 4.8 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 GBG77222.1 - 2.3e-20 71.0 5.2 3e-05 23.8 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GBG77222.1 - 2.4e-15 55.4 0.9 0.0055 16.8 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG77222.1 - 7.4e-15 54.4 3.7 0.00035 20.2 0.0 4.5 3 1 1 4 4 4 4 TPR repeat TPR_16 PF13432.6 GBG77222.1 - 8.4e-14 51.9 5.2 1e-06 29.3 0.1 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 GBG77222.1 - 4.7e-13 48.5 4.9 0.008 16.5 0.0 5.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 GBG77222.1 - 1.8e-11 44.0 0.2 0.0082 16.3 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG77222.1 - 1e-08 35.3 3.6 0.032 15.0 0.1 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG77222.1 - 2.5e-08 33.4 4.4 0.14 12.3 0.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG77222.1 - 3e-08 33.8 0.7 0.092 13.4 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG77222.1 - 1.8e-06 28.2 2.8 0.096 13.0 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 GBG77222.1 - 6.4e-05 22.3 0.5 0.014 14.6 0.0 3.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG77222.1 - 0.00017 22.0 5.3 0.067 13.7 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 GBG77222.1 - 0.027 14.8 1.6 0.6 10.5 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GBG77222.1 - 0.3 10.6 1.3 0.81 9.2 0.0 2.4 3 0 0 3 3 3 0 SHNi-TPR PTS_IIA PF02255.16 GBG77222.1 - 0.5 10.5 2.7 0.88 9.7 0.1 2.2 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit PBP1_TM PF14812.6 GBG77223.1 - 7.1 7.1 8.8 12 6.4 0.8 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Integrase_H2C2 PF17921.1 GBG77224.1 - 1.1e-16 60.7 0.1 2.2e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77224.1 - 2e-07 31.2 0.0 6.6e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG77224.1 - 4.1e-06 26.6 0.0 8.3e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77224.1 - 2.2e-05 25.0 0.0 6.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77224.1 - 0.0024 18.4 0.0 0.009 16.6 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77224.1 - 0.026 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4187 PF13821.6 GBG77224.1 - 0.039 13.7 2.0 0.15 11.9 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG77224.1 - 0.049 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG77224.1 - 0.097 12.9 0.2 0.4 10.9 0.2 2.1 1 1 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG77225.1 - 2.2e-28 98.2 0.0 4.9e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77225.1 - 2e-26 92.9 0.2 4.1e-21 75.5 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_1 PF00515.28 GBG77225.1 - 8.9e-24 82.3 4.4 2.8e-10 39.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG77225.1 - 4.9e-20 70.0 2.7 4e-08 32.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG77225.1 - 2.4e-17 62.3 4.6 1.9e-08 33.9 0.0 3.4 1 1 2 3 3 3 2 TPR repeat TPR_8 PF13181.6 GBG77225.1 - 3.7e-16 57.9 2.1 7.7e-06 25.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat RT_RNaseH PF17917.1 GBG77225.1 - 1.2e-15 57.7 0.0 2.4e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TPR_17 PF13431.6 GBG77225.1 - 4.7e-14 51.7 0.7 9.9e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG77225.1 - 1.7e-11 44.6 0.0 1.2e-05 25.9 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG77225.1 - 5.4e-10 39.4 0.8 1.2e-05 25.5 0.4 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG77225.1 - 1e-06 28.9 0.4 0.33 11.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG77225.1 - 2.8e-06 27.4 0.0 0.0015 18.6 0.0 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GBG77225.1 - 3.2e-05 23.3 0.1 0.95 9.0 0.0 3.3 3 0 0 3 3 3 2 SHNi-TPR TPR_7 PF13176.6 GBG77225.1 - 0.00025 20.8 0.9 0.15 12.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG77225.1 - 0.00067 20.1 0.3 0.053 14.0 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG77225.1 - 0.00079 19.2 0.6 2 8.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG77225.1 - 0.0024 18.5 0.0 2.5 9.1 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG77225.1 - 0.043 14.0 0.7 0.089 13.0 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 GBG77225.1 - 0.21 11.7 3.6 11 6.2 1.3 3.2 2 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain RT_RNaseH PF17917.1 GBG77226.1 - 6.2e-19 68.2 0.0 1.5e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77226.1 - 9.9e-19 67.2 0.0 2.5e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77226.1 - 1.4e-18 66.7 0.0 2.9e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77226.1 - 5.9e-10 39.4 0.0 2.1e-09 37.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG77226.1 - 7.5e-10 38.7 0.1 2.1e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG77226.1 - 5.4e-07 29.5 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77226.1 - 9e-06 26.2 0.0 2.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77226.1 - 4.6e-05 23.9 0.1 0.00014 22.3 0.0 1.9 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77226.1 - 0.00088 19.1 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG77226.1 - 0.023 15.0 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG77226.1 - 0.081 13.2 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG77227.1 - 9e-30 103.8 0.1 1.6e-29 103.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77227.1 - 8.7e-26 89.9 0.0 2.2e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77227.1 - 6.9e-24 84.2 0.0 1.8e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77227.1 - 3.7e-18 65.4 0.3 9.4e-18 64.1 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77227.1 - 3.2e-09 37.0 0.0 1.2e-08 35.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG77227.1 - 9.4e-06 26.2 0.0 2.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG77227.1 - 1.9e-05 24.5 0.0 3.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG77227.1 - 8.1e-05 23.1 0.0 0.00028 21.4 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77227.1 - 0.029 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease FAE1_CUT1_RppA PF08392.12 GBG77227.1 - 0.037 13.3 0.3 2.9 7.1 0.1 2.5 3 0 0 3 3 3 0 FAE1/Type III polyketide synthase-like protein Senescence_reg PF04520.13 GBG77227.1 - 0.17 12.7 1.4 0.63 10.9 1.4 2.0 1 0 0 1 1 1 0 Senescence regulator RVT_1 PF00078.27 GBG77229.1 - 2.6e-29 102.3 0.0 5.1e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77229.1 - 1.4e-13 50.7 0.1 3.7e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77229.1 - 0.0017 18.6 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase eIF-1a PF01176.19 GBG77229.1 - 0.03 14.1 0.1 0.078 12.8 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 SSP160 PF06933.11 GBG77229.1 - 2.3 6.3 8.8 3.3 5.8 8.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 gag-asp_proteas PF13975.6 GBG77232.1 - 6.5e-06 26.6 0.0 1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77232.1 - 6.9e-05 23.4 0.0 0.00015 22.3 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG77232.1 - 0.0031 17.3 0.5 0.0053 16.5 0.5 1.3 1 0 0 1 1 1 1 Aspartyl protease pP_pnuc_2 PF18166.1 GBG77232.1 - 0.025 14.7 0.1 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease RVP PF00077.20 GBG77232.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease Cwf_Cwc_15 PF04889.12 GBG77233.1 - 2.6 7.7 15.6 4.2 7.0 15.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG77233.1 - 6 6.2 19.2 9.4 5.6 19.2 1.2 1 0 0 1 1 1 0 SDA1 zf-FCS PF06467.14 GBG77234.1 - 0.22 11.5 2.9 0.3 11.1 0.2 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF659 PF04937.15 GBG77235.1 - 1.3e-28 99.7 0.0 2.6e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG77235.1 - 6.1e-12 45.2 0.2 1.8e-11 43.7 0.2 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TPR_1 PF00515.28 GBG77235.1 - 1.6e-08 34.0 0.0 0.0016 18.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Asp_protease_2 PF13650.6 GBG77235.1 - 2.9e-08 34.2 0.0 8.2e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG77235.1 - 4.2e-07 29.8 0.0 9.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG77235.1 - 2.9e-06 27.8 0.0 8.5e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TPR_2 PF07719.17 GBG77235.1 - 1e-05 25.3 0.0 0.18 12.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG77235.1 - 0.00066 19.8 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Asp_protease PF09668.10 GBG77235.1 - 0.0011 18.7 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease TPR_17 PF13431.6 GBG77235.1 - 0.0065 16.8 0.0 0.39 11.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG77235.1 - 0.017 15.1 0.0 1.1 9.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5082 PF16888.5 GBG77235.1 - 0.025 14.8 0.9 0.025 14.8 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) TPR_12 PF13424.6 GBG77235.1 - 0.035 14.4 0.1 0.3 11.4 0.1 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF1664 PF07889.12 GBG77235.1 - 0.11 12.5 4.7 0.77 9.8 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 GBG77235.1 - 0.13 12.4 3.2 0.28 11.3 3.2 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UDPG_MGDP_dh_C PF03720.15 GBG77235.1 - 0.13 12.7 0.0 0.6 10.6 0.0 2.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TolA_bind_tri PF16331.5 GBG77235.1 - 0.65 10.1 6.7 3.1 8.0 6.7 2.1 1 1 0 1 1 1 0 TolA binding protein trimerisation SlyX PF04102.12 GBG77235.1 - 2 9.1 7.5 0.57 10.8 2.0 2.5 1 1 1 2 2 2 0 SlyX RT_RNaseH PF17917.1 GBG77236.1 - 1.9e-23 82.7 0.0 3.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77236.1 - 4.9e-23 81.1 0.0 8.1e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77236.1 - 6e-06 25.9 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77237.1 - 2.1e-23 82.2 0.0 5.7e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77237.1 - 4.1e-21 75.2 0.0 9.9e-21 74.0 0.0 1.7 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77237.1 - 1.1e-14 54.3 0.6 1.1e-14 54.3 0.6 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77237.1 - 1.4e-10 41.1 0.7 1.8e-05 24.4 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG77237.1 - 2.9e-09 37.1 0.0 8.2e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG77237.1 - 0.00058 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG77237.1 - 0.0028 18.2 0.0 0.0056 17.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77237.1 - 0.0056 17.3 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG77237.1 - 0.014 15.6 0.0 0.04 14.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG77237.1 - 0.042 13.7 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease APG17 PF04108.12 GBG77237.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF4192 PF13830.6 GBG77238.1 - 0.37 10.8 10.3 0.5 10.4 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) RVT_1 PF00078.27 GBG77240.1 - 1.7e-36 125.8 0.1 2.9e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77240.1 - 5.7e-31 106.9 0.0 1.4e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77240.1 - 6.7e-31 106.3 0.0 1.8e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG77240.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CSRNP_N PF16019.5 GBG77241.1 - 0.65 9.9 12.5 0.039 13.9 4.2 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Peptidase_S64 PF08192.11 GBG77241.1 - 3 6.2 7.7 3.7 5.9 7.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 FAM60A PF15396.6 GBG77241.1 - 4.3 7.3 18.0 13 5.7 17.9 1.8 1 1 0 1 1 1 0 Protein Family FAM60A TPR_1 PF00515.28 GBG77242.1 - 5e-10 38.8 0.2 8.7e-10 38.0 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GBG77242.1 - 1.8e-08 33.9 0.1 4.1e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG77242.1 - 8.8e-08 31.7 0.2 1.6e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG77242.1 - 1.1e-06 28.2 0.1 2.2e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG77242.1 - 5.2e-05 22.8 0.5 0.05 13.3 0.0 2.2 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.6 GBG77242.1 - 6.6e-05 23.1 0.1 0.00012 22.3 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG77242.1 - 0.00047 20.4 0.3 0.0013 19.0 0.2 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_5 PF12688.7 GBG77242.1 - 0.0027 17.9 0.4 0.0034 17.6 0.4 1.2 1 0 0 1 1 1 1 Tetratrico peptide repeat TPR_9 PF13371.6 GBG77242.1 - 0.0029 17.7 0.2 0.0053 16.9 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG77242.1 - 0.0056 17.3 0.2 0.011 16.4 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF357 PF04010.13 GBG77242.1 - 0.014 15.5 0.2 0.024 14.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF357) MIT PF04212.18 GBG77242.1 - 0.053 13.6 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 GBG77242.1 - 0.08 13.6 0.3 0.2 12.4 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG77242.1 - 0.14 13.0 0.1 0.27 12.2 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 GBG77243.1 - 1.1e-34 118.4 0.0 2.1e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77243.1 - 3.1e-30 104.5 0.0 6.2e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77243.1 - 4.9e-20 71.4 0.1 9.9e-20 70.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77243.1 - 1.6e-08 34.3 0.3 2.6e-08 33.7 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG77243.1 - 0.026 14.7 1.1 0.047 13.9 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger RVT_1 PF00078.27 GBG77245.1 - 2.8e-27 95.7 0.1 9.2e-27 94.0 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77245.1 - 2.7e-16 59.4 0.0 9.3e-16 57.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77245.1 - 2e-15 56.6 0.1 4.4e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77245.1 - 3.1e-08 33.8 0.0 7.8e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG77245.1 - 7.3e-08 32.7 0.0 2.1e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG77245.1 - 4e-07 29.9 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77245.1 - 3.4e-05 24.4 0.0 7.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77245.1 - 0.0063 17.0 0.0 0.019 15.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Fez1 PF06818.15 GBG77245.1 - 0.0091 16.5 0.3 0.025 15.0 0.3 1.7 1 0 0 1 1 1 1 Fez1 DUF659 PF04937.15 GBG77246.1 - 5e-07 29.7 0.0 8.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) NYN_YacP PF05991.11 GBG77247.1 - 0.19 11.7 0.1 0.28 11.1 0.1 1.2 1 0 0 1 1 1 0 YacP-like NYN domain RVT_1 PF00078.27 GBG77249.1 - 2.9e-29 102.2 0.1 5e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG77249.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease EzrA PF06160.12 GBG77249.1 - 0.18 9.9 7.9 0.36 8.9 7.9 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Retrotrans_gag PF03732.17 GBG77249.1 - 0.31 11.3 2.6 1.7 9.0 0.0 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein DUF2870 PF11069.8 GBG77249.1 - 0.5 10.8 2.1 1.2 9.6 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DUF4140 PF13600.6 GBG77249.1 - 1.2 9.6 10.2 7.3 7.1 1.2 3.7 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Exonuc_VII_L PF02601.15 GBG77249.1 - 1.7 8.1 4.8 3.3 7.2 4.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Snapin_Pallidin PF14712.6 GBG77249.1 - 2.5 8.6 13.3 1.4 9.4 0.1 3.0 3 0 0 3 3 3 0 Snapin/Pallidin Trans_reg_C PF00486.28 GBG77251.1 - 0.035 14.2 0.3 0.099 12.7 0.3 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal NifQ PF04891.12 GBG77251.1 - 5.9 7.2 7.2 2.2 8.6 0.9 3.0 2 1 1 3 3 3 0 NifQ Baculo_PEP_C PF04513.12 GBG77251.1 - 8 6.5 6.7 2 8.5 1.5 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RT_RNaseH PF17917.1 GBG77252.1 - 2.5e-32 111.3 0.1 3.9e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77252.1 - 9e-32 109.1 0.1 1.4e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77252.1 - 2e-12 47.0 0.0 4.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77252.1 - 7.3e-08 32.2 0.1 1.3e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77253.1 - 8e-21 74.0 0.0 2e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77253.1 - 5.8e-20 71.5 0.0 1.6e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77253.1 - 5.9e-16 58.3 0.1 1.2e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77253.1 - 2.2e-07 31.1 0.0 9.2e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG77253.1 - 2.3e-07 30.6 2.1 1.7e-06 27.7 0.0 2.6 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG77253.1 - 0.025 14.8 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG77254.1 - 3.1e-39 134.8 0.0 5.4e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GAGA_bind PF06217.12 GBG77255.1 - 4 7.6 11.9 6.4 7.0 11.9 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RVT_1 PF00078.27 GBG77256.1 - 5.1e-31 107.9 0.1 8.5e-31 107.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PET PF06297.14 GBG77256.1 - 0.13 12.6 0.3 0.48 10.8 0.3 1.9 1 0 0 1 1 1 0 PET Domain LOH1CR12 PF10158.9 GBG77256.1 - 0.15 12.1 1.2 0.24 11.4 0.2 1.9 2 0 0 2 2 2 0 Tumour suppressor protein Cep57_MT_bd PF06657.13 GBG77256.1 - 7.1 7.2 8.7 1.6 9.2 0.4 3.1 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ATP-synt_10 PF05176.14 GBG77257.1 - 1.6e-07 30.8 0.1 2.4e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 ATP10 protein RVT_1 PF00078.27 GBG77257.1 - 8.4e-06 25.5 0.0 1.2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nup35_RRM_2 PF14605.6 GBG77258.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RR_TM4-6 PF06459.12 GBG77259.1 - 0.11 12.3 35.6 0.14 12.0 35.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 GBG77259.1 - 0.69 8.1 59.8 1.1 7.4 59.8 1.3 1 0 0 1 1 1 0 Nop14-like family PPR PF01535.20 GBG77260.1 - 1e-39 132.0 1.7 1.7e-06 27.9 0.0 8.5 9 0 0 9 9 8 7 PPR repeat PPR_2 PF13041.6 GBG77260.1 - 5.9e-32 109.6 0.0 2.7e-06 27.5 0.0 7.2 3 3 4 7 7 7 7 PPR repeat family PPR_1 PF12854.7 GBG77260.1 - 1.7e-25 88.4 0.0 3.2e-06 26.7 0.0 7.7 8 0 0 8 8 8 4 PPR repeat PPR_3 PF13812.6 GBG77260.1 - 7.3e-18 64.4 0.0 0.0003 20.8 0.0 5.1 2 2 5 7 7 7 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG77260.1 - 1.4e-11 44.2 0.0 0.0002 20.8 0.0 2.7 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 GBG77260.1 - 0.00034 20.4 3.2 0.43 10.7 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG77260.1 - 0.00059 20.3 0.0 3.5 8.2 0.0 4.0 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG77260.1 - 0.00099 19.7 10.5 2.7 9.0 0.1 5.7 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 GBG77260.1 - 0.0013 19.1 6.5 11 7.0 0.0 5.7 6 0 0 6 6 4 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GBG77260.1 - 0.055 13.4 0.6 7.2 6.5 0.0 3.2 3 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 GBG77260.1 - 0.092 13.0 2.2 8.4 6.8 0.1 4.4 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG77260.1 - 0.13 12.9 0.3 4.1 8.3 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat PMBR PF09373.10 GBG77260.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Pseudomurein-binding repeat TPR_1 PF00515.28 GBG77260.1 - 0.18 11.7 0.0 5.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 GBG77261.1 - 3.4e-37 128.2 0.0 7.1e-37 127.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77261.1 - 2.3e-36 125.5 0.0 3.6e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG77261.1 - 0.022 14.7 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RVT_1 PF00078.27 GBG77262.1 - 2.9e-12 46.6 0.0 4.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTPRCAP PF15713.5 GBG77262.1 - 0.027 14.8 12.1 0.06 13.6 12.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GBG77262.1 - 0.12 10.6 7.6 0.15 10.2 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG77262.1 - 0.95 8.8 11.0 1.5 8.2 11.0 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG77262.1 - 2.3 6.4 9.6 3.2 6.0 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase_Tyr PF07714.17 GBG77264.1 - 1.6e-07 30.9 0.0 2.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77264.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SDA1 PF05285.12 GBG77265.1 - 9.6 5.5 19.6 12 5.2 19.6 1.1 1 0 0 1 1 1 0 SDA1 Pkinase_Tyr PF07714.17 GBG77267.1 - 8.1e-38 130.2 0.0 2e-37 128.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77267.1 - 1.4e-34 119.6 0.0 2.6e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG77267.1 - 0.0071 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Lin-8 PF03353.15 GBG77269.1 - 1.5 8.3 5.8 2.5 7.6 5.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RNA_pol_3_Rpc31 PF11705.8 GBG77271.1 - 0.012 15.9 9.8 0.016 15.5 9.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 GBG77271.1 - 0.021 13.1 9.0 0.02 13.1 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG77271.1 - 0.035 13.5 9.8 0.037 13.4 9.8 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 GBG77271.1 - 0.051 13.5 6.7 0.082 12.8 6.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 GBG77271.1 - 0.13 11.6 10.2 0.17 11.2 10.2 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GBG77271.1 - 0.25 9.6 6.6 0.23 9.7 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG77271.1 - 0.63 8.1 14.5 0.81 7.7 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 GBG77271.1 - 0.71 9.2 11.7 0.88 8.8 11.7 1.1 1 0 0 1 1 1 0 BUD22 DDHD PF02862.17 GBG77271.1 - 0.79 9.8 4.7 1.1 9.4 4.8 1.3 1 1 0 1 1 1 0 DDHD domain RRN3 PF05327.11 GBG77271.1 - 7.6 5.0 7.6 9 4.7 7.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM76 PF16046.5 GBG77276.1 - 0.39 10.0 7.1 0.24 10.7 5.5 1.4 1 1 0 1 1 1 0 FAM76 protein HSP90 PF00183.18 GBG77277.1 - 3.1e-236 785.3 26.8 4.1e-236 784.9 26.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GBG77277.1 - 1.9e-14 54.1 0.1 3.6e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GBG77277.1 - 2.1e-10 40.5 0.1 7e-10 38.9 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 GBG77277.1 - 0.024 14.6 0.1 0.066 13.2 0.1 1.7 1 0 0 1 1 1 0 Tumour suppressor protein zf-CCHC PF00098.23 GBG77278.1 - 2.9e-09 36.6 2.8 6.7e-09 35.4 2.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG77278.1 - 0.00034 20.3 0.7 0.00064 19.5 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle V_ATPase_I PF01496.19 GBG77278.1 - 0.4 8.5 11.1 0.5 8.2 11.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MRP-S31 PF15433.6 GBG77278.1 - 0.65 9.6 13.3 0.77 9.4 13.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 FapA PF03961.13 GBG77278.1 - 2.4 6.7 8.3 3.3 6.2 8.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-CCHC_6 PF15288.6 GBG77278.1 - 2.6 8.0 8.0 0.3 11.0 3.0 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG77278.1 - 3.3 7.5 5.4 0.54 10.0 1.2 1.9 2 0 0 2 2 2 0 Zinc knuckle Pkinase_Tyr PF07714.17 GBG77280.1 - 1.1e-38 133.1 0.0 2.4e-38 131.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77280.1 - 2.1e-37 128.9 0.0 4.1e-37 128.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG77280.1 - 0.00034 20.6 0.1 0.0032 17.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG77280.1 - 0.049 12.4 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Nop14 PF04147.12 GBG77281.1 - 0.99 7.5 5.8 1.2 7.3 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG77281.1 - 4.9 5.3 8.1 6.4 4.9 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Integrase_H2C2 PF17921.1 GBG77282.1 - 1.4e-10 41.1 0.0 3.9e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77282.1 - 4.9e-08 33.2 0.0 1.3e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG77282.1 - 9.3e-06 26.1 0.0 2.8e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77282.1 - 0.00047 20.7 0.3 0.0012 19.5 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG77282.1 - 0.01 15.6 0.1 0.064 13.1 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 GBG77282.1 - 0.029 14.7 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase_Tyr PF07714.17 GBG77283.1 - 6e-38 130.6 0.0 9.7e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77283.1 - 2.1e-35 122.3 0.0 3.5e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG77283.1 - 0.00013 22.0 0.0 0.00036 20.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG77283.1 - 0.0049 15.7 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 GBG77284.1 - 1.4e-36 126.1 0.0 2.7e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77284.1 - 1e-32 113.6 0.0 2.1e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG77284.1 - 0.038 13.9 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GRP PF07172.11 GBG77284.1 - 0.35 11.6 0.0 0.35 11.6 0.0 3.2 3 0 0 3 3 3 0 Glycine rich protein family Ecl1 PF12855.7 GBG77284.1 - 5.9 8.0 57.9 1.8 9.7 14.9 3.4 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins CDC45 PF02724.14 GBG77285.1 - 0.6 8.3 10.2 0.81 7.9 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein GCP5-Mod21 PF14609.6 GBG77285.1 - 2 6.7 4.1 2.6 6.3 4.1 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 RR_TM4-6 PF06459.12 GBG77285.1 - 3.6 7.3 6.2 5.9 6.6 6.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-CCHC PF00098.23 GBG77286.1 - 4.4e-06 26.5 3.8 1.1e-05 25.3 3.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG77286.1 - 0.043 13.8 0.7 0.12 12.4 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle WD40_alt PF14077.6 GBG77286.1 - 0.068 13.0 2.7 8.3 6.4 1.2 3.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF2937 PF11157.8 GBG77286.1 - 0.075 12.7 0.9 0.62 9.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) zf-CCHC_2 PF13696.6 GBG77286.1 - 0.3 11.0 5.0 0.56 10.1 5.0 1.5 1 0 0 1 1 1 0 Zinc knuckle CCDC92 PF14916.6 GBG77286.1 - 1.2 9.0 15.2 4.3 7.2 0.0 5.9 5 1 2 7 7 7 0 Coiled-coil domain of unknown function Shugoshin_N PF07558.11 GBG77286.1 - 1.9 8.5 9.9 7.4 6.5 0.1 3.8 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Speriolin_N PF15058.6 GBG77286.1 - 4.4 7.4 6.2 47 4.0 2.9 3.1 2 1 0 2 2 2 0 Speriolin N terminus SGL PF08450.12 GBG77287.1 - 0.00057 19.5 0.3 1.1 8.7 0.0 3.0 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region SKG6 PF08693.10 GBG77287.1 - 1.4 8.4 10.9 3.1 7.3 10.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Myb_DNA-bind_4 PF13837.6 GBG77288.1 - 1.7e-06 28.3 0.5 7.8e-05 23.0 0.1 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77288.1 - 0.18 12.1 1.5 0.55 10.6 0.2 2.5 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase PF00069.25 GBG77289.1 - 2.4e-35 122.2 0.0 4.3e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG77289.1 - 3.5e-35 121.5 0.0 1.2e-34 119.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG77289.1 - 0.0017 18.3 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG77289.1 - 0.045 12.5 0.0 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pex14_N PF04695.13 GBG77289.1 - 0.068 13.8 0.5 0.068 13.8 0.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRIMA1 PF16101.5 GBG77289.1 - 0.66 10.0 2.8 0.81 9.7 1.0 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Chromo PF00385.24 GBG77290.1 - 2.1e-10 40.4 0.0 3.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG77290.1 - 7.5e-06 25.6 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bac_globin PF01152.21 GBG77290.1 - 0.077 13.1 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Bacterial-like globin Ribosomal_L22e PF01776.17 GBG77291.1 - 6.4e-23 81.2 0.3 7.8e-23 80.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family ADP_PFK_GK PF04587.15 GBG77291.1 - 0.0072 14.9 0.0 0.0082 14.8 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Pkinase_Tyr PF07714.17 GBG77292.1 - 4.9e-29 101.4 0.0 5.5e-27 94.7 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG77292.1 - 9.3e-26 90.8 0.0 1.1e-23 84.0 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Herpes_gE PF02480.16 GBG77292.1 - 0.0048 15.7 0.0 0.0069 15.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E PsbX PF06596.11 GBG77292.1 - 0.27 11.3 2.3 0.67 10.0 2.3 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Pkinase PF00069.25 GBG77293.1 - 3.1e-27 95.6 0.0 5.3e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG77293.1 - 9e-27 94.0 0.0 2.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase NESP55 PF06390.12 GBG77293.1 - 0.0018 17.9 9.3 0.0031 17.1 9.3 1.3 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) CAP_N PF01213.19 GBG77293.1 - 0.0095 15.5 0.9 0.022 14.3 0.9 1.6 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CobT PF06213.12 GBG77293.1 - 0.02 14.3 18.2 0.032 13.6 18.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Myc_N PF01056.18 GBG77293.1 - 0.023 14.6 1.6 0.053 13.4 1.6 1.7 1 0 0 1 1 1 0 Myc amino-terminal region PSK PF06404.12 GBG77293.1 - 0.084 13.9 3.2 0.22 12.6 3.2 1.7 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) FAM176 PF14851.6 GBG77293.1 - 0.42 10.3 9.7 0.86 9.3 9.7 1.5 1 0 0 1 1 1 0 FAM176 family DUF3311 PF11755.8 GBG77293.1 - 0.56 10.2 2.9 1.6 8.7 2.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) DUF2796 PF10986.8 GBG77293.1 - 1.4 8.9 7.8 2.5 8.1 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Paf1 PF03985.13 GBG77293.1 - 1.5 7.8 13.9 2.2 7.2 13.9 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 GBG77293.1 - 1.5 8.5 6.1 2.8 7.7 6.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sigma70_ner PF04546.13 GBG77293.1 - 1.6 8.5 15.4 2.7 7.8 15.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Mpp10 PF04006.12 GBG77293.1 - 2.9 6.2 18.8 4.4 5.6 18.8 1.1 1 0 0 1 1 1 0 Mpp10 protein RPN2_C PF18004.1 GBG77293.1 - 3.4 7.6 8.5 6 6.8 8.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SDA1 PF05285.12 GBG77293.1 - 5.8 6.2 21.7 9.8 5.5 21.7 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GBG77293.1 - 6.6 5.8 31.0 12 4.9 31.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 GBG77293.1 - 7.8 6.1 18.4 15 5.3 18.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG77293.1 - 8.4 4.5 18.3 13 3.9 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 GBG77293.1 - 9 5.4 11.8 13 4.9 11.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 GBG77293.1 - 9.7 4.3 22.8 14 3.8 22.8 1.1 1 0 0 1 1 1 0 Nop14-like family API5 PF05918.11 GBG77294.1 - 0.006 15.5 3.2 0.0072 15.2 3.2 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) E7 PF00527.18 GBG77294.1 - 0.067 13.4 5.8 0.12 12.6 5.8 1.4 1 0 0 1 1 1 0 E7 protein, Early protein Laps PF10169.9 GBG77294.1 - 0.33 11.5 7.1 0.43 11.2 7.1 1.1 1 0 0 1 1 1 0 Learning-associated protein TRAP_alpha PF03896.16 GBG77294.1 - 1 8.5 3.5 1.2 8.2 3.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paf1 PF03985.13 GBG77294.1 - 1.3 7.9 10.8 1.6 7.6 10.8 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 GBG77294.1 - 6.8 4.8 6.1 8.2 4.6 6.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Bindin PF02084.15 GBG77294.1 - 8.6 6.6 16.6 12 6.0 16.6 1.3 1 0 0 1 1 1 0 Bindin SDA1 PF05285.12 GBG77295.1 - 0.11 11.9 20.0 0.13 11.6 20.0 1.1 1 0 0 1 1 1 0 SDA1 DUF2201_N PF13203.6 GBG77295.1 - 0.2 11.2 5.1 0.24 11.0 5.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4820 PF16091.5 GBG77295.1 - 0.22 10.9 2.9 0.35 10.2 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RNA_pol_Rpc4 PF05132.14 GBG77295.1 - 1.1 9.7 4.7 1.7 9.0 4.7 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nucleo_P87 PF07267.11 GBG77295.1 - 1.8 7.3 4.3 2 7.2 4.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF913 PF06025.12 GBG77295.1 - 2 7.3 4.1 2.3 7.1 4.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 GBG77295.1 - 3.5 7.0 15.9 4.8 6.5 15.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 GBG77295.1 - 4.2 5.5 17.9 5.5 5.2 17.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG77295.1 - 6.8 5.9 21.6 8.2 5.7 21.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG77295.1 - 7 4.7 25.4 8 4.5 25.4 1.0 1 0 0 1 1 1 0 Nop14-like family VIR_N PF15912.5 GBG77295.1 - 9.2 5.8 12.3 12 5.3 12.3 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal DDE_Tnp_4 PF13359.6 GBG77296.1 - 3.1e-29 101.7 0.0 6.1e-29 100.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77296.1 - 1.4e-14 54.2 0.0 2.2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77296.1 - 0.0018 18.0 0.4 1.1 8.9 0.0 3.3 4 0 0 4 4 4 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG77297.1 - 4.7e-10 39.7 1.2 3.6e-08 33.7 0.5 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG77297.1 - 0.019 15.0 0.6 0.049 13.7 0.6 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77297.1 - 0.085 13.2 0.2 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_C48 PF02902.19 GBG77298.1 - 1.9e-10 40.9 0.9 2.9e-10 40.3 0.9 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF507 PF04368.13 GBG77298.1 - 0.0048 16.8 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF507) DUF659 PF04937.15 GBG77300.1 - 3.1e-07 30.4 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RecX PF02631.16 GBG77300.1 - 0.061 13.8 3.0 1.5 9.3 0.0 2.9 3 0 0 3 3 3 0 RecX family COR PF16095.5 GBG77300.1 - 0.14 12.0 0.1 15 5.3 0.0 2.4 2 0 0 2 2 2 0 C-terminal of Roc, COR, domain RVT_1 PF00078.27 GBG77301.1 - 3.5e-26 92.1 0.0 6e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77301.1 - 2.2e-24 85.4 0.0 7.7e-24 83.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77301.1 - 2.1e-20 72.9 0.0 6e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77301.1 - 7.9e-16 57.9 0.1 2.7e-15 56.2 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77301.1 - 1.5e-09 38.1 0.0 5.4e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG77301.1 - 5.5e-06 26.9 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG77301.1 - 8.3e-06 25.6 0.0 2.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG77301.1 - 2.4e-05 24.8 0.0 8.6e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG77301.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG77301.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG77302.1 - 3.8e-15 56.1 0.0 8.1e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Menin PF05053.13 GBG77303.1 - 2.8 6.2 6.8 3 6.1 6.8 1.0 1 0 0 1 1 1 0 Menin DUF4554 PF15091.6 GBG77303.1 - 6.5 5.5 8.1 7.7 5.3 8.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) RR_TM4-6 PF06459.12 GBG77303.1 - 6.8 6.4 14.5 7.6 6.3 14.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF659 PF04937.15 GBG77304.1 - 2.1e-07 30.9 0.0 4.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Ribosomal_60s PF00428.19 GBG77304.1 - 0.00067 20.2 3.6 0.00067 20.2 3.6 3.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Pkinase_Tyr PF07714.17 GBG77305.1 - 3.3e-37 128.2 0.0 6.8e-37 127.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77305.1 - 3.8e-32 111.7 0.0 8.6e-32 110.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG77305.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG77305.1 - 0.033 13.0 0.0 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF3328 PF11807.8 GBG77305.1 - 0.31 10.8 0.7 0.87 9.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF659 PF04937.15 GBG77307.1 - 6.5e-10 39.1 0.0 1.4e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Topo_Zn_Ribbon PF08272.11 GBG77307.1 - 0.065 12.9 0.3 0.15 11.7 0.3 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG77307.1 - 0.14 12.2 1.9 0.29 11.3 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Pkinase_Tyr PF07714.17 GBG77308.1 - 9.9e-13 48.0 0.0 7.2e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG77308.1 - 2e-09 37.2 0.0 2.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Exonuc_VII_L PF02601.15 GBG77310.1 - 0.15 11.6 8.1 0.23 11.0 8.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0184 PF03670.13 GBG77310.1 - 0.44 11.0 2.4 1.1 9.7 0.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) NPV_P10 PF05531.12 GBG77310.1 - 3.9 8.0 5.7 8.4 6.9 0.8 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 GBG77310.1 - 4.5 7.3 19.8 1.4 8.9 17.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus N6_N4_Mtase PF01555.18 GBG77312.1 - 3.4e-09 36.8 0.0 5.4e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 DNA methylase Pkinase_Tyr PF07714.17 GBG77313.1 - 1.6e-51 175.1 0.0 1.4e-33 116.3 0.0 2.8 2 2 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG77313.1 - 1.3e-50 172.3 0.0 5.4e-32 111.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 GBG77313.1 - 4.6e-08 32.3 0.0 0.0067 15.3 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 GBG77313.1 - 3.5e-07 30.4 0.0 0.02 14.8 0.0 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GBG77313.1 - 0.078 12.5 0.0 5.8 6.4 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL gag-asp_proteas PF13975.6 GBG77314.1 - 8.2e-06 26.3 0.1 2.8e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77314.1 - 0.0018 18.8 0.0 0.0071 17.0 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG77314.1 - 0.0076 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Phage_head_fibr PF11133.8 GBG77314.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Head fiber protein RVP_2 PF08284.11 GBG77314.1 - 0.023 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG77314.1 - 0.13 12.0 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like CAF1-p150_C2 PF15539.6 GBG77314.1 - 1.2 8.5 4.0 2.9 7.3 4.0 1.5 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Topo_Zn_Ribbon PF08272.11 GBG77315.1 - 0.068 12.8 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like CAF1-p150_C2 PF15539.6 GBG77315.1 - 5.2 6.4 7.6 1.1 8.6 4.1 1.6 2 0 0 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Pkinase_Tyr PF07714.17 GBG77316.1 - 3.5e-39 134.7 0.0 1.6e-38 132.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77316.1 - 3.2e-34 118.5 0.0 5.9e-34 117.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG77316.1 - 0.005 16.8 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family TMEM154 PF15102.6 GBG77316.1 - 0.11 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Pkinase_fungal PF17667.1 GBG77316.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 GBG77318.1 - 2.4e-26 92.7 0.0 3.7e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG77318.1 - 1.5e-16 60.4 0.0 2.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG77318.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RL PF17797.1 GBG77318.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 RL domain DUF659 PF04937.15 GBG77320.1 - 4e-23 82.0 0.0 6.1e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG77320.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG77321.1 - 1.6e-18 67.0 0.0 3.3e-18 66.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) ECH_1 PF00378.20 GBG77322.1 - 1.1e-18 67.5 7.7 4.4e-16 58.9 0.0 2.7 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GBG77322.1 - 2.7e-07 30.4 0.0 2.7e-07 30.4 0.0 3.4 2 2 2 4 4 4 2 Enoyl-CoA hydratase/isomerase GLTSCR1 PF15249.6 GBG77322.1 - 0.018 15.4 4.7 0.049 14.1 4.7 1.7 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein FYVE PF01363.21 GBG77322.1 - 0.063 13.4 0.7 0.16 12.1 0.7 1.6 1 0 0 1 1 1 0 FYVE zinc finger Bac_A_amyl_C PF18612.1 GBG77322.1 - 0.12 12.2 0.0 25 4.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial Alpha amylase C-terminal domain RT_RNaseH_2 PF17919.1 GBG77323.1 - 2.7e-26 91.5 0.0 4.5e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77323.1 - 8.5e-25 87.1 0.0 1.5e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77323.1 - 1.1e-09 38.2 0.0 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG77323.1 - 0.47 8.7 8.8 0.67 8.2 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG77323.1 - 0.72 9.2 14.0 0.15 11.5 10.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 GBG77323.1 - 3.2 7.1 15.5 6.2 6.1 15.5 1.4 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG77323.1 - 8.3 5.1 8.1 14 4.3 8.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein N2227 PF07942.12 GBG77324.1 - 0.19 10.9 1.5 3.7 6.7 0.3 2.0 1 1 1 2 2 2 0 N2227-like protein Usp PF00582.26 GBG77325.1 - 5e-30 104.8 3.5 1.6e-29 103.3 0.7 2.3 2 1 0 2 2 2 1 Universal stress protein family CENP-X PF09415.10 GBG77326.1 - 0.023 15.0 2.7 0.067 13.5 2.7 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Trimer_CC PF08954.11 GBG77327.1 - 0.0007 19.1 0.7 0.0044 16.5 0.7 2.4 1 0 0 1 1 1 1 Trimerisation motif TolA_bind_tri PF16331.5 GBG77327.1 - 0.45 10.6 11.3 0.41 10.8 0.6 3.8 3 1 0 3 3 3 0 TolA binding protein trimerisation HALZ PF02183.18 GBG77327.1 - 0.68 10.2 7.2 3.5 7.9 0.7 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper DCA16 PF15349.6 GBG77328.1 - 0.12 12.0 0.2 0.2 11.2 0.1 1.5 1 1 0 1 1 1 0 DDB1- and CUL4-associated factor 16 RGS-like PF09128.11 GBG77328.1 - 0.94 9.2 7.7 0.32 10.7 4.9 1.6 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain zf-CCCH PF00642.24 GBG77330.1 - 2.8e-21 74.9 45.5 4e-08 33.0 7.2 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GBG77330.1 - 1.1e-14 53.8 46.5 0.00071 19.3 6.4 4.3 4 0 0 4 4 4 4 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GBG77330.1 - 1.7e-14 53.3 39.3 0.00024 21.0 4.4 4.5 4 0 0 4 4 4 4 Zinc finger domain KH_1 PF00013.29 GBG77330.1 - 4.1e-13 49.0 0.4 7e-13 48.2 0.4 1.4 1 0 0 1 1 1 1 KH domain zf-CCCH_2 PF14608.6 GBG77330.1 - 1.2e-09 38.2 38.7 0.0068 16.8 5.5 4.4 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger oligo_HPY PF08352.12 GBG77330.1 - 3.5e-06 27.4 15.0 0.12 12.9 0.5 4.3 4 0 0 4 4 4 3 Oligopeptide/dipeptide transporter, C-terminal region Torus PF16131.5 GBG77330.1 - 3.7e-06 27.6 19.2 0.021 15.5 1.1 4.1 2 1 2 4 4 4 2 Torus domain KH_2 PF07650.17 GBG77330.1 - 0.0011 18.7 0.1 0.002 17.9 0.1 1.3 1 0 0 1 1 1 1 KH domain FAD_oxidored PF12831.7 GBG77330.1 - 0.044 13.1 1.5 0.33 10.3 1.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase ATX_III PF08098.11 GBG77330.1 - 0.14 12.2 0.3 0.14 12.2 0.3 4.1 4 0 0 4 4 4 0 Anemonia sulcata toxin III family KH_5 PF13184.6 GBG77330.1 - 0.2 11.8 0.1 0.36 11.0 0.1 1.4 1 0 0 1 1 1 0 NusA-like KH domain zf-CCCH_3 PF15663.5 GBG77330.1 - 0.47 10.7 16.8 7.6 6.8 0.4 4.3 4 0 0 4 4 4 0 Zinc-finger containing family Lustrin_cystein PF14625.6 GBG77330.1 - 8.4 6.9 21.8 2.2 8.7 1.5 4.2 4 0 0 4 4 4 0 Lustrin, cysteine-rich repeated domain SpoIIP PF07454.11 GBG77331.1 - 0.65 9.4 9.7 2.5 7.5 0.9 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4366 PF14283.6 GBG77331.1 - 1.3 9.1 4.9 0.72 9.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) TFB6 PF17110.5 GBG77331.1 - 2.9 7.6 15.0 0.94 9.2 4.3 2.5 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH zf-CCCH PF00642.24 GBG77332.1 - 4.5e-21 74.2 40.1 6.3e-09 35.5 7.1 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) KH_1 PF00013.29 GBG77332.1 - 2e-13 49.9 0.3 3.2e-13 49.3 0.3 1.3 1 0 0 1 1 1 1 KH domain zf_CCCH_4 PF18345.1 GBG77332.1 - 1.6e-11 43.9 39.0 5e-05 23.2 5.1 4.4 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 GBG77332.1 - 4.7e-11 42.2 40.2 0.00017 21.3 5.2 4.3 4 0 0 4 4 4 4 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GBG77332.1 - 2.8e-06 27.6 29.0 0.015 15.7 4.1 4.4 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GBG77332.1 - 0.00016 22.4 10.2 0.0074 17.0 0.1 3.3 3 0 0 3 3 3 1 Torus domain oligo_HPY PF08352.12 GBG77332.1 - 0.0011 19.4 18.5 0.19 12.3 0.5 4.2 3 1 0 3 3 3 2 Oligopeptide/dipeptide transporter, C-terminal region KH_2 PF07650.17 GBG77332.1 - 0.0067 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_5 PF13184.6 GBG77332.1 - 0.061 13.4 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 NusA-like KH domain Rer1 PF03248.13 GBG77334.1 - 2e-68 229.5 6.4 2.4e-68 229.2 6.4 1.1 1 0 0 1 1 1 1 Rer1 family Halogen_Hydrol PF10112.9 GBG77334.1 - 1.2 9.1 2.7 19 5.2 2.0 2.0 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein eIF-3c_N PF05470.12 GBG77335.1 - 2.2e-216 719.8 4.0 3.1e-216 719.3 4.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 GBG77335.1 - 7e-16 58.6 0.4 3.7e-15 56.3 0.0 2.4 3 0 0 3 3 3 1 PCI domain FtsQ PF03799.15 GBG77335.1 - 0.057 14.2 2.7 3.9 8.3 0.3 4.0 4 1 0 4 4 4 0 Cell division protein FtsQ PDT PF00800.18 GBG77335.1 - 0.062 13.1 1.8 0.13 12.1 0.2 2.1 2 0 0 2 2 2 0 Prephenate dehydratase Fic PF02661.18 GBG77335.1 - 0.13 13.2 0.9 0.95 10.4 0.4 2.8 2 0 0 2 2 2 0 Fic/DOC family zf-RING_2 PF13639.6 GBG77336.1 - 8.5e-06 26.0 1.0 2e-05 24.8 1.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GBG77336.1 - 1.4e-05 25.3 0.4 3.6e-05 23.9 0.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GBG77336.1 - 2.6e-05 24.0 0.6 5.1e-05 23.1 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG77336.1 - 2.8e-05 23.8 0.1 7.9e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GBG77336.1 - 4.4e-05 23.2 1.2 9.2e-05 22.2 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG77336.1 - 0.0049 16.9 0.5 0.011 15.7 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 GBG77336.1 - 0.0057 16.2 1.3 0.022 14.4 1.3 1.9 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GBG77336.1 - 0.031 14.3 0.9 0.063 13.2 0.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG77336.1 - 0.066 13.1 1.0 0.17 11.8 1.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 GBG77336.1 - 0.095 13.0 0.3 0.23 11.8 0.3 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 GBG77336.1 - 0.24 11.3 0.9 0.48 10.3 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RVT_1 PF00078.27 GBG77337.1 - 9.5e-19 67.8 0.7 5.6e-15 55.5 0.2 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Spore_coat_CotO PF14153.6 GBG77337.1 - 0.0057 16.6 3.1 0.0088 16.0 3.1 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Integrase_H2C2 PF17921.1 GBG77338.1 - 3.6e-17 62.2 0.1 7.7e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77338.1 - 2.6e-13 50.2 0.0 5.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG77338.1 - 0.015 15.0 0.1 0.073 12.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG77338.1 - 0.019 15.2 0.0 0.063 13.5 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG77338.1 - 0.021 14.7 0.0 0.064 13.2 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain LSDAT_euk PF18139.1 GBG77339.1 - 0.17 11.2 1.3 0.33 10.3 1.3 1.4 1 0 0 1 1 1 0 SLOG in TRPM rve PF00665.26 GBG77340.1 - 1e-15 58.0 0.0 2.1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG77340.1 - 7.8e-13 48.3 0.1 2.8e-12 46.5 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG77340.1 - 6.4e-05 22.9 0.7 0.017 15.2 0.2 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG77340.1 - 0.0013 18.5 0.0 0.0038 17.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG77340.1 - 0.0023 18.2 0.0 0.0051 17.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77341.1 - 6.3e-25 87.1 0.0 1.4e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77341.1 - 3.7e-24 85.5 0.1 7e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77341.1 - 5.6e-23 81.2 0.0 1.7e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG77342.1 - 1.6e-05 24.8 3.2 4e-05 23.5 3.2 1.7 1 0 0 1 1 1 1 Zinc knuckle FNIP_N PF14636.6 GBG77342.1 - 0.0045 18.0 0.3 0.0059 17.6 0.3 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein N-terminus zf-CCHC_4 PF14392.6 GBG77342.1 - 0.02 14.6 2.1 0.046 13.5 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle TMEM171 PF15471.6 GBG77342.1 - 0.18 10.7 0.4 0.27 10.2 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Ribosomal_60s PF00428.19 GBG77342.1 - 2.9 8.5 13.4 0.23 12.1 7.5 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Eapp_C PF10238.9 GBG77342.1 - 7.3 6.7 7.9 0.34 11.0 0.9 2.0 2 0 0 2 2 2 0 E2F-associated phosphoprotein zf-CCHC_6 PF15288.6 GBG77343.1 - 0.083 12.7 2.0 0.25 11.2 2.0 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF1564 PF07600.11 GBG77344.1 - 0.02 14.6 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG77345.1 - 1.5e-29 103.1 0.0 2.4e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77345.1 - 6.8e-22 77.4 0.0 1.4e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77345.1 - 1.4e-18 67.1 0.0 3.6e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77345.1 - 2.9e-18 65.7 0.1 5.9e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77345.1 - 2.9e-09 37.2 0.1 9.5e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG77345.1 - 3.7e-07 30.0 0.0 7.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77345.1 - 3.9e-07 30.6 0.0 7.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77345.1 - 4.8e-05 23.8 0.0 8.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG77345.1 - 5.9e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG77345.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Acetyltransf_10 PF13673.7 GBG77346.1 - 4.7e-05 23.3 0.0 8.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG77346.1 - 0.00028 20.8 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein FAA_hydrolase PF01557.18 GBG77346.1 - 0.037 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family Acetyltransf_1 PF00583.25 GBG77346.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 GBG77346.1 - 0.15 12.8 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_C2 PF00648.21 GBG77348.1 - 2.2e-85 286.3 0.1 2.6e-85 286.0 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 GBG77348.1 - 3e-15 56.7 0.0 5e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III rve PF00665.26 GBG77349.1 - 3.1e-06 27.4 0.0 9e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF4187 PF13821.6 GBG77349.1 - 0.0031 17.3 0.6 0.0079 16.0 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG77349.1 - 0.0065 16.7 0.2 0.0065 16.7 0.2 2.6 4 0 0 4 4 4 1 Retrotransposon gag protein rve_3 PF13683.6 GBG77349.1 - 0.048 13.4 0.2 0.13 12.0 0.2 1.8 1 0 0 1 1 1 0 Integrase core domain DUF3526 PF12040.8 GBG77350.1 - 0.044 14.3 0.3 0.089 13.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) DUF659 PF04937.15 GBG77351.1 - 1.3e-31 109.6 0.1 2.8e-31 108.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG77353.1 - 9.6e-31 106.2 0.1 2.3e-30 105.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77353.1 - 2.2e-30 104.6 0.0 5.2e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77353.1 - 7.3e-24 84.5 0.4 5e-21 75.3 0.4 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77353.1 - 4.3e-19 68.4 0.6 9.9e-19 67.2 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG77353.1 - 2.8e-07 30.4 0.0 5.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77353.1 - 3e-06 27.8 0.0 6.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77353.1 - 0.00013 22.4 0.1 0.00042 20.8 0.1 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG77353.1 - 0.00044 20.4 0.1 0.0017 18.5 0.1 2.1 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG77353.1 - 0.0018 18.0 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG77353.1 - 2.2 7.9 14.2 0.37 10.4 0.1 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase COX16 PF14138.6 GBG77353.1 - 5.1 7.7 12.2 1.7e+02 2.8 11.7 3.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Herpes_LMP1 PF05297.11 GBG77354.1 - 0.72 9.0 5.3 0.85 8.8 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2070 PF09843.9 GBG77354.1 - 1.9 6.7 5.9 2.2 6.5 5.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CENP-K PF11802.8 GBG77355.1 - 0.032 13.8 3.6 0.051 13.2 3.6 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Retrotrans_gag PF03732.17 GBG77355.1 - 0.043 14.1 0.2 0.043 14.1 0.2 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein Lipin_mid PF16876.5 GBG77355.1 - 0.057 13.6 1.2 0.32 11.2 0.0 2.6 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain TFIIA PF03153.13 GBG77355.1 - 4.7 7.1 17.4 0.81 9.6 10.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RVT_1 PF00078.27 GBG77356.1 - 1.5e-29 103.1 0.0 2.3e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG77356.1 - 7.5e-11 42.3 0.0 2.1e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG77356.1 - 4.6e-08 33.6 0.0 1e-07 32.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77356.1 - 6.8e-08 33.0 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77356.1 - 4.3e-06 26.5 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG77356.1 - 6.1e-06 26.2 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG77356.1 - 1.3e-05 25.0 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG77356.1 - 5.9e-05 22.9 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG77357.1 - 2e-13 50.6 0.4 6.8e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG77358.1 - 2.5e-33 115.5 0.1 4.5e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77358.1 - 9.7e-15 54.4 0.2 3.7e-14 52.6 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG77358.1 - 3.7e-14 52.9 0.0 8.3e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG77358.1 - 1.5e-11 44.5 2.1 2.3e-11 43.9 0.9 2.0 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG77358.1 - 1.4e-07 31.4 0.0 3.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG77358.1 - 0.00032 21.2 0.0 0.0018 18.8 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG77358.1 - 0.0018 18.3 1.4 0.17 12.0 0.1 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG77358.1 - 0.0019 18.4 0.0 0.0076 16.4 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG77358.1 - 0.0025 18.4 3.0 0.015 16.0 0.0 3.4 4 0 0 4 4 3 1 Aspartyl protease Asp_protease PF09668.10 GBG77358.1 - 0.009 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease CCDC85 PF10226.9 GBG77358.1 - 0.047 13.4 0.4 0.13 12.0 0.4 1.7 1 0 0 1 1 1 0 CCDC85 family DUF2385 PF09539.10 GBG77358.1 - 0.048 14.2 0.2 0.67 10.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) ABC_tran_CTD PF16326.5 GBG77358.1 - 1.5 9.1 7.1 0.27 11.5 1.3 2.9 2 0 0 2 2 1 0 ABC transporter C-terminal domain zf-CCHC PF00098.23 GBG77359.1 - 0.083 13.0 2.3 0.18 11.9 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle SLATT_5 PF18160.1 GBG77359.1 - 1.5 8.1 3.4 4.4 6.6 3.4 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Myb_DNA-bind_4 PF13837.6 GBG77360.1 - 1.2e-05 25.6 3.0 1.2e-05 25.6 3.0 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77360.1 - 0.079 13.3 4.4 0.063 13.6 1.4 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG77360.1 - 3.5 7.8 8.9 0.53 10.4 4.4 1.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Cwf_Cwc_15 PF04889.12 GBG77361.1 - 0.0011 18.8 29.8 0.0011 18.8 29.8 2.4 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 GBG77361.1 - 1 8.4 21.2 1.7 7.8 21.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop53 PF07767.11 GBG77361.1 - 1.1 8.5 46.7 0.13 11.6 31.8 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF3527 PF12043.8 GBG77361.1 - 1.1 8.7 7.3 2.1 7.8 6.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) CDC45 PF02724.14 GBG77361.1 - 1.2 7.4 32.0 0.19 9.9 27.9 1.6 2 0 0 2 2 2 0 CDC45-like protein Striatin PF08232.12 GBG77361.1 - 5 7.7 27.9 6.9 7.2 19.6 2.9 2 0 0 2 2 2 0 Striatin family BUD22 PF09073.10 GBG77361.1 - 5.3 6.3 36.3 0.19 11.0 29.7 1.8 2 0 0 2 2 2 0 BUD22 DUF2722 PF10846.8 GBG77361.1 - 8.1 5.3 13.1 18 4.2 13.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Ank PF00023.30 GBG77362.1 - 3.5e-11 43.0 0.2 0.0004 20.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 GBG77362.1 - 1.2e-10 40.7 0.0 0.0001 22.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 GBG77362.1 - 6.6e-09 36.2 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GBG77362.1 - 7.8e-09 35.6 0.6 4.4e-05 23.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GBG77362.1 - 1.6e-06 28.6 0.0 2.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Sporozoite_P67 PF05642.11 GBG77362.1 - 0.026 12.6 3.7 0.041 12.0 3.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GCN5L1 PF06320.13 GBG77362.1 - 0.073 13.2 4.4 0.084 13.0 2.9 1.8 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) YabA PF06156.13 GBG77362.1 - 0.1 13.2 0.1 0.37 11.5 0.0 1.9 2 0 0 2 2 2 0 Initiation control protein YabA FUSC PF04632.12 GBG77362.1 - 0.32 9.5 4.5 0.7 8.4 0.1 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family FSA_C PF10479.9 GBG77362.1 - 0.45 8.6 1.8 0.63 8.1 1.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Redoxin PF08534.10 GBG77363.1 - 6e-34 116.9 0.0 9.1e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GBG77363.1 - 2.6e-13 50.0 0.0 3.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family IF-2B PF01008.17 GBG77364.1 - 2.9e-74 249.8 0.1 5.2e-74 249.0 0.0 1.4 2 0 0 2 2 2 1 Initiation factor 2 subunit family APH PF01636.23 GBG77364.1 - 1.8e-17 64.1 0.0 3.9e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GBG77364.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 GBG77364.1 - 0.0029 17.0 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Fructosamin_kin PF03881.14 GBG77364.1 - 0.039 13.2 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase RT_RNaseH PF17917.1 GBG77365.1 - 9.2e-17 61.3 0.0 2.7e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77365.1 - 1.1e-14 54.3 0.0 2.7e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77365.1 - 2.6e-09 36.9 0.0 4.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG77365.1 - 1.3e-07 32.0 0.0 7.7e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG77365.1 - 0.00063 20.0 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77365.1 - 0.00095 19.8 0.0 0.003 18.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Raftlin PF15250.6 GBG77365.1 - 0.071 11.9 0.2 0.16 10.7 0.2 1.5 1 0 0 1 1 1 0 Raftlin RXLR PF16810.5 GBG77365.1 - 0.098 13.1 3.2 3.6 8.0 2.3 2.7 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Asp_protease PF09668.10 GBG77365.1 - 0.2 11.5 0.3 0.39 10.5 0.3 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG77366.1 - 6.2e-17 61.8 0.0 1.2e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77366.1 - 6.2e-15 55.1 0.0 1.3e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77366.1 - 1.1e-09 38.1 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG77367.1 - 4.7e-08 33.3 0.3 8.8e-08 32.4 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG77367.1 - 0.0043 17.1 1.2 0.01 15.9 1.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG77368.1 - 2.1e-07 31.2 1.0 1.4e-06 28.6 0.6 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG77371.1 - 3.5e-12 46.3 0.1 9.5e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CSRNP_N PF16019.5 GBG77373.1 - 2.5 7.9 10.3 0.22 11.4 1.5 2.0 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Integrase_H2C2 PF17921.1 GBG77374.1 - 1.9e-15 56.7 0.1 4.9e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77374.1 - 0.00011 22.3 0.0 0.00031 20.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG77374.1 - 0.0013 19.0 0.0 0.0056 16.9 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger RXLR PF16810.5 GBG77374.1 - 2.3 8.6 3.9 11 6.5 0.1 2.4 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity CDC45 PF02724.14 GBG77376.1 - 0.94 7.7 23.1 1 7.6 23.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 GBG77376.1 - 2.2 8.6 30.7 2.6 8.3 30.7 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF1168 PF06658.12 GBG77376.1 - 2.3 8.0 37.0 3 7.6 37.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF2052 PF09747.9 GBG77376.1 - 2.5 8.2 24.7 3.8 7.6 24.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pal1 PF08316.11 GBG77376.1 - 2.8 8.7 7.3 4.2 8.1 7.3 1.4 1 0 0 1 1 1 0 Pal1 cell morphology protein RR_TM4-6 PF06459.12 GBG77376.1 - 2.9 7.6 25.0 3.5 7.4 25.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Membralin PF09746.9 GBG77376.1 - 3 6.8 7.0 3.2 6.7 7.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 GBG77376.1 - 4.4 6.2 13.7 4.9 6.1 13.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 GBG77376.1 - 5 5.9 10.7 5.3 5.8 10.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 GBG77376.1 - 5.2 5.7 18.9 5.5 5.7 18.9 1.0 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 GBG77376.1 - 6 7.0 8.7 7.4 6.7 8.7 1.3 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.6 GBG77376.1 - 6.6 6.7 12.8 7.7 6.5 12.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SAPS PF04499.15 GBG77376.1 - 8.5 5.0 13.7 8.5 5.0 13.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HSP70 PF00012.20 GBG77376.1 - 8.8 4.4 16.0 8.7 4.4 16.0 1.0 1 0 0 1 1 1 0 Hsp70 protein 17kDa_Anti_2 PF16998.5 GBG77377.1 - 0.0047 16.8 1.8 1.8 8.5 0.0 2.9 1 1 2 3 3 3 2 17 kDa outer membrane surface antigen Gp138_N PF18352.1 GBG77377.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain RVT_1 PF00078.27 GBG77378.1 - 5.2e-35 121.0 0.2 8e-35 120.4 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77378.1 - 6.4e-13 48.6 0.0 3.4e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG77378.1 - 2.8e-07 30.4 0.0 7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77378.1 - 4.2e-06 27.3 0.0 9.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77378.1 - 0.0003 21.3 0.0 0.001 19.5 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG77378.1 - 0.0012 18.7 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG77378.1 - 0.0037 17.0 0.0 0.01 15.6 0.0 1.7 1 1 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG77378.1 - 0.0053 17.0 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4392 PF14336.6 GBG77378.1 - 0.03 13.8 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) RT_RNaseH_2 PF17919.1 GBG77379.1 - 1.2e-32 111.9 0.0 2.4e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77379.1 - 4.1e-28 97.7 0.0 9e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77379.1 - 1.8e-23 83.2 0.0 4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77379.1 - 3.3e-18 65.5 0.2 7.4e-18 64.4 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77379.1 - 7.9e-09 35.7 0.0 8.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain BRAP2 PF07576.12 GBG77380.1 - 1.9e-31 108.2 0.0 3.2e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 GBG77380.1 - 4.1e-18 65.5 9.7 1.2e-17 64.0 9.7 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 GBG77380.1 - 1.7e-08 34.7 6.8 1.7e-08 34.7 6.8 2.4 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG77380.1 - 3.2e-07 30.1 5.9 3.2e-07 30.1 5.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG77380.1 - 3.4e-06 27.2 5.2 3.4e-06 27.2 5.2 2.5 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GBG77380.1 - 7.2e-06 25.8 9.0 4.5e-05 23.2 9.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG77380.1 - 1.4e-05 24.9 4.8 1.4e-05 24.9 4.8 2.5 3 0 0 3 3 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG77380.1 - 0.00012 22.0 7.7 0.00026 21.0 6.3 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 GBG77380.1 - 0.0004 20.1 3.9 0.0013 18.4 3.9 2.0 1 0 0 1 1 1 1 RING-like zinc finger AAA_23 PF13476.6 GBG77380.1 - 0.0033 18.0 0.3 0.0049 17.4 0.3 1.3 1 0 0 1 1 1 1 AAA domain E2F_CC-MB PF16421.5 GBG77380.1 - 0.006 16.9 0.2 0.015 15.7 0.1 1.7 1 1 1 2 2 2 1 E2F transcription factor CC-MB domain zf-RING_6 PF14835.6 GBG77380.1 - 0.021 14.7 4.0 0.062 13.2 4.0 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein UPF0242 PF06785.11 GBG77380.1 - 1 9.4 12.3 1.6 8.8 12.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SHE3 PF17078.5 GBG77380.1 - 1.1 9.0 13.4 10 5.8 13.5 2.2 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 GBG77380.1 - 1.2 9.7 18.3 2.1 8.9 18.3 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-C3HC4_3 PF13920.6 GBG77380.1 - 1.9 8.4 18.8 0.26 11.2 7.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sigma70_ner PF04546.13 GBG77380.1 - 4 7.3 10.9 0.63 9.9 2.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region SlyX PF04102.12 GBG77380.1 - 9.2 7.0 8.2 3 8.5 1.3 2.7 1 1 1 2 2 2 0 SlyX Cadherin_4 PF17803.1 GBG77381.1 - 1.7 9.3 8.8 2.3 8.9 8.8 1.3 1 0 0 1 1 1 0 Bacterial cadherin-like domain HTH_Tnp_Tc5 PF03221.16 GBG77382.1 - 1.4e-11 44.3 0.4 3.6e-11 42.9 0.4 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 GBG77382.1 - 2.1e-10 40.5 0.0 4.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 GBG77382.1 - 0.0003 21.0 0.6 0.0045 17.3 0.1 2.9 3 0 0 3 3 3 1 Transposase CENP-B_N PF04218.13 GBG77382.1 - 0.01 15.5 0.0 0.048 13.3 0.0 2.2 2 1 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DUF4207 PF13904.6 GBG77382.1 - 0.031 14.0 3.3 0.05 13.3 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) NAD_binding_1 PF00175.21 GBG77383.1 - 6.1e-05 23.6 0.0 0.00013 22.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ribosomal_L22 PF00237.19 GBG77384.1 - 1.8e-08 34.5 2.3 4.2e-05 23.7 0.2 2.5 3 0 0 3 3 3 2 Ribosomal protein L22p/L17e RT_RNaseH_2 PF17919.1 GBG77385.1 - 5.4e-24 84.1 0.0 1.3e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77385.1 - 1.2e-23 83.3 0.0 2.8e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77385.1 - 8.6e-20 70.6 0.1 1.6e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77385.1 - 1.4e-08 34.9 0.0 4.6e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG77385.1 - 3.5e-07 30.8 0.0 9e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG77385.1 - 1.9e-06 27.7 0.0 4.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG77385.1 - 2.5e-05 24.7 0.0 8.8e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77385.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG77385.1 - 0.033 14.4 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG77385.1 - 0.083 13.2 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Macoilin PF09726.9 GBG77386.1 - 5.8 5.3 10.0 6.8 5.1 10.0 1.0 1 0 0 1 1 1 0 Macoilin family Ribosomal_60s PF00428.19 GBG77387.1 - 0.11 13.1 5.8 0.5 11.0 5.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 GBG77387.1 - 0.13 10.7 0.1 0.15 10.5 0.1 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein LRR_4 PF12799.7 GBG77388.1 - 2.8e-08 33.9 11.9 1.3 9.6 0.2 9.7 9 2 6 15 15 15 3 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG77388.1 - 1.4e-05 24.8 3.5 2.4e-05 24.1 1.3 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GBG77388.1 - 1.7e-05 24.6 0.4 6.6e-05 22.7 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 GBG77388.1 - 3.7e-05 23.2 1.9 3.7e-05 23.2 1.9 1.9 2 0 0 2 2 2 1 F-box LRR_2 PF07723.13 GBG77388.1 - 0.0064 17.1 0.9 1.8 9.4 0.0 3.5 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 GBG77388.1 - 0.03 14.4 18.1 77 3.7 0.0 9.6 11 0 0 11 11 11 0 Leucine Rich repeat SDA1 PF05285.12 GBG77390.1 - 0.00026 20.5 24.4 0.00031 20.3 24.4 1.1 1 0 0 1 1 1 1 SDA1 YL1 PF05764.13 GBG77390.1 - 0.0033 17.6 25.7 0.0048 17.1 25.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein BUD22 PF09073.10 GBG77390.1 - 0.0099 15.3 26.3 0.015 14.7 26.3 1.2 1 0 0 1 1 1 1 BUD22 Lin-8 PF03353.15 GBG77390.1 - 0.023 14.3 11.0 0.029 13.9 11.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG77390.1 - 0.053 11.7 25.7 0.064 11.5 25.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4551 PF15087.6 GBG77390.1 - 0.16 10.8 1.2 0.19 10.5 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 GBG77390.1 - 0.46 9.2 12.0 0.55 8.9 12.0 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG77390.1 - 0.48 9.1 8.8 0.58 8.9 8.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LAP1C PF05609.12 GBG77390.1 - 1.6 7.8 13.2 1.9 7.5 13.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 GBG77390.1 - 2.3 6.2 9.6 2.6 6.1 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.6 GBG77390.1 - 2.4 6.8 10.3 2.9 6.6 10.3 1.2 1 0 0 1 1 1 0 Raftlin Smg8_Smg9 PF10220.9 GBG77390.1 - 3.1 6.0 9.6 3.8 5.7 9.6 1.1 1 0 0 1 1 1 0 Smg8_Smg9 TMEM214 PF10151.9 GBG77391.1 - 1.2 7.6 4.7 0.68 8.3 3.3 1.3 1 1 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator AnfO_nitrog PF09582.10 GBG77392.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Adap_comp_sub PF00928.21 GBG77393.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Adaptor complexes medium subunit family Peptidase_C48 PF02902.19 GBG77394.1 - 1.3e-22 80.8 0.0 5.9e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Dicty_REP PF05086.12 GBG77395.1 - 0.2 9.6 7.7 0.25 9.3 7.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2076 PF09849.9 GBG77395.1 - 0.61 10.1 12.2 0.8 9.7 12.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) zf-CCHC PF00098.23 GBG77397.1 - 1.3e-06 28.2 2.7 2.7e-06 27.2 2.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG77397.1 - 0.021 14.5 2.6 0.047 13.4 2.6 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger CpXC PF14353.6 GBG77397.1 - 0.029 14.4 0.5 9.9 6.2 0.0 2.5 2 0 0 2 2 2 0 CpXC protein Prok-RING_1 PF14446.6 GBG77397.1 - 0.047 13.6 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF4551 PF15087.6 GBG77397.1 - 8.9 5.0 19.3 17 4.1 19.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RVT_1 PF00078.27 GBG77398.1 - 3.3e-19 69.3 0.1 7.9e-19 68.0 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG77398.1 - 9.8e-07 28.6 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77398.1 - 1.4e-06 28.8 0.0 3.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77398.1 - 4.8e-05 23.9 0.0 0.00011 22.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG77398.1 - 0.0019 18.3 0.0 0.006 16.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG77398.1 - 0.0021 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG77398.1 - 0.0065 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4187 PF13821.6 GBG77398.1 - 0.09 12.6 1.5 0.31 10.9 1.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DUF1697 PF08002.11 GBG77398.1 - 6 7.3 6.3 1.8 9.0 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1697) HSP70 PF00012.20 GBG77400.1 - 8.1e-261 866.5 5.0 9.2e-261 866.3 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG77400.1 - 6.9e-15 54.7 0.5 9e-14 51.0 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Zincin_2 PF10103.9 GBG77400.1 - 0.12 11.6 0.3 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Zincin-like metallopeptidase Ntox15 PF15604.6 GBG77400.1 - 0.53 10.4 7.3 1.1 9.3 7.3 1.5 1 0 0 1 1 1 0 Novel toxin 15 Pkinase_Tyr PF07714.17 GBG77401.1 - 2.7e-24 85.8 0.0 7.4e-24 84.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77401.1 - 1.6e-23 83.4 0.0 7.8e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain NHL PF01436.21 GBG77401.1 - 0.13 12.4 3.1 2.2 8.4 0.2 3.2 3 0 0 3 3 3 0 NHL repeat DEK_C PF08766.11 GBG77401.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain TFIIS_C PF01096.18 GBG77402.1 - 2.1e-17 62.7 1.6 2.8e-17 62.3 1.6 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) zf-TFIIB PF13453.6 GBG77402.1 - 0.0031 16.8 1.4 0.0055 16.0 1.4 1.4 1 0 0 1 1 1 1 Transcription factor zinc-finger zf-Mss51 PF13824.6 GBG77402.1 - 0.0082 16.2 4.0 0.3 11.2 0.3 2.2 1 1 1 2 2 2 2 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.6 GBG77402.1 - 0.026 13.9 3.9 0.74 9.3 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain VP_N-CPKC PF11475.8 GBG77402.1 - 0.028 14.3 5.7 1.4 8.9 0.3 2.4 2 0 0 2 2 2 0 Virion protein N terminal domain Zn-ribbon_8 PF09723.10 GBG77402.1 - 0.029 14.5 2.6 1.2 9.3 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 GBG77402.1 - 0.031 14.2 2.1 0.077 13.0 2.1 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 GBG77402.1 - 0.031 14.7 6.1 0.13 12.7 2.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain RNA_POL_M_15KD PF02150.16 GBG77402.1 - 0.033 14.1 2.4 0.32 10.9 2.4 2.2 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit Terminase_GpA PF05876.12 GBG77402.1 - 0.1 11.2 0.3 0.1 11.1 0.3 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-C2H2_3 PF13878.6 GBG77402.1 - 0.23 11.3 5.3 0.93 9.4 0.3 2.3 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO PADR1 PF08063.12 GBG77402.1 - 0.28 11.0 2.9 7.4 6.4 0.1 2.2 2 0 0 2 2 2 0 PADR1 (NUC008) domain DUF1610 PF07754.11 GBG77402.1 - 0.34 10.9 6.1 7.7 6.6 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) C1_4 PF07975.12 GBG77402.1 - 0.38 11.0 3.9 4.6 7.5 3.9 2.1 1 1 0 1 1 1 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 GBG77402.1 - 0.4 10.6 5.3 3.7 7.5 1.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 GBG77402.1 - 0.55 10.4 4.9 5.8 7.2 5.2 2.1 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf_C2H2_10 PF18414.1 GBG77402.1 - 0.65 9.6 6.6 6 6.5 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-C4_Topoisom PF01396.19 GBG77402.1 - 1 9.2 8.3 7.2 6.5 8.3 2.1 1 1 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zf_UBZ PF18439.1 GBG77402.1 - 1.7 8.3 4.6 3.5 7.3 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 GBG77402.1 - 4.3 8.0 6.6 4.9 7.8 2.4 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pkinase_Tyr PF07714.17 GBG77403.1 - 5.5e-43 147.1 0.0 9.2e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77403.1 - 1.9e-37 129.1 0.0 3.3e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG77403.1 - 4.2e-05 23.6 0.0 0.0008 19.4 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family NHL PF01436.21 GBG77403.1 - 6e-05 22.9 0.9 0.14 12.3 0.3 2.8 2 0 0 2 2 2 2 NHL repeat SGL PF08450.12 GBG77403.1 - 0.002 17.7 0.0 0.5 9.9 0.0 3.6 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Kdo PF06293.14 GBG77403.1 - 0.0095 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Lactonase PF10282.9 GBG77403.1 - 0.044 13.0 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Pkinase_fungal PF17667.1 GBG77403.1 - 0.12 11.2 0.3 0.24 10.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase HTH_ABP1_N PF18107.1 GBG77404.1 - 0.013 15.2 0.3 0.023 14.4 0.3 1.3 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Period_C PF12114.8 GBG77404.1 - 0.068 12.8 11.2 0.057 13.0 3.8 2.1 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DDE_Tnp_4 PF13359.6 GBG77406.1 - 4.6e-13 49.1 0.1 1e-12 48.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77406.1 - 1.2e-06 28.3 0.0 4.2e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77406.1 - 0.052 13.2 0.1 0.57 9.8 0.0 2.1 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG77408.1 - 2.7e-07 30.9 1.2 5.6e-07 29.9 1.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG77408.1 - 0.0083 16.2 2.1 0.018 15.1 2.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG77409.1 - 9.9e-32 109.8 0.0 1.3e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77409.1 - 1.8e-16 60.3 0.0 2.7e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77409.1 - 0.00088 19.0 1.3 0.44 10.2 0.0 2.5 3 0 0 3 3 3 2 Transposase DDE domain Pkinase PF00069.25 GBG77410.1 - 1.4e-34 119.7 0.0 2.3e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG77410.1 - 5.5e-30 104.5 0.0 8.7e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG77410.1 - 0.13 12.1 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 GBG77410.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 ABC1 family PfkB PF00294.24 GBG77412.1 - 1.8e-20 73.4 0.6 3.9e-19 69.1 0.3 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Pkinase PF00069.25 GBG77413.1 - 1.8e-44 152.1 0.0 4.8e-22 78.6 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG77413.1 - 8e-22 77.8 0.0 6.7e-10 38.7 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Myb_DNA-bind_4 PF13837.6 GBG77414.1 - 6.3e-08 32.9 2.0 2.8e-07 30.8 2.4 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77414.1 - 0.0015 18.8 1.1 0.0044 17.3 1.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3472 PF11958.8 GBG77414.1 - 0.0043 17.5 1.5 0.0096 16.4 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Myb_DNA-bind_6 PF13921.6 GBG77414.1 - 0.014 15.6 0.6 0.03 14.6 0.6 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG77414.1 - 0.027 14.6 0.3 0.07 13.2 0.3 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Pox_F15 PF04596.12 GBG77414.1 - 0.057 13.2 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus protein F15 BUD22 PF09073.10 GBG77415.1 - 0.087 12.1 16.1 0.11 11.9 16.1 1.0 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG77415.1 - 1.6 7.4 5.2 2 7.1 5.2 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG77415.1 - 3.1 6.0 15.1 4 5.6 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG77415.1 - 3.8 5.5 17.2 4.6 5.2 17.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Merozoite_SPAM PF07133.11 GBG77415.1 - 4.2 7.3 28.8 5.7 6.9 28.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 GBG77415.1 - 4.6 6.6 18.2 5.9 6.2 18.2 1.1 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 GBG77415.1 - 7.2 5.7 8.1 11 5.1 8.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Glyco_transf_34 PF05637.12 GBG77416.1 - 3.2e-08 33.6 0.0 2.8e-06 27.2 0.0 2.8 2 1 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family SPX PF03105.19 GBG77416.1 - 0.84 9.5 8.1 0.32 10.9 4.3 1.9 2 0 0 2 2 2 0 SPX domain Myb_DNA-bind_4 PF13837.6 GBG77417.1 - 4.1e-07 30.3 2.1 6e-07 29.8 0.1 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77417.1 - 0.015 15.6 1.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Dsh_C PF12316.8 GBG77417.1 - 0.061 13.7 1.3 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Integrase_H2C2 PF17921.1 GBG77418.1 - 2.5e-14 53.1 0.1 6.5e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77418.1 - 2.4e-05 24.0 0.0 4.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG77418.1 - 9.6e-05 22.9 0.5 0.00026 21.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77418.1 - 0.00035 21.2 0.2 0.0012 19.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.10 GBG77418.1 - 0.00048 20.3 0.0 0.0014 18.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG77418.1 - 0.057 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG77419.1 - 3.4e-12 46.4 0.0 4.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpc4 PF05132.14 GBG77419.1 - 0.43 11.0 2.3 0.85 10.0 2.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 GBG77419.1 - 0.6 8.8 3.6 0.74 8.5 3.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG77419.1 - 3.5 5.7 24.1 4.6 5.3 24.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG77419.1 - 3.9 6.8 25.8 0.62 9.4 22.2 1.4 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 GBG77419.1 - 4.5 5.4 18.6 6.3 5.0 18.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG77420.1 - 4.3e-26 91.8 0.1 6e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77420.1 - 1.7e-11 44.0 0.0 5.6e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG77420.1 - 9.4e-06 25.4 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77420.1 - 2.7e-05 24.7 0.0 5.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77420.1 - 4e-05 24.1 0.0 8.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77420.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG77420.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.7 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase HIP1_clath_bdg PF16515.5 GBG77421.1 - 0.0031 18.1 5.8 0.0031 18.1 5.8 2.6 2 1 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ERM PF00769.19 GBG77421.1 - 0.045 13.6 17.9 0.062 13.1 17.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FliD_N PF02465.18 GBG77421.1 - 0.065 13.9 0.3 0.065 13.9 0.3 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus YscO-like PF16789.5 GBG77421.1 - 0.071 13.1 8.8 0.083 12.9 8.1 1.4 1 1 0 1 1 1 0 YscO-like protein Retrotrans_gag PF03732.17 GBG77421.1 - 0.092 13.0 0.2 0.092 13.0 0.2 2.6 1 1 0 2 2 2 0 Retrotransposon gag protein Barttin PF15462.6 GBG77421.1 - 0.33 10.7 4.1 0.12 12.1 0.6 1.8 1 1 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) YabA PF06156.13 GBG77421.1 - 0.47 11.1 6.5 1.7 9.3 0.3 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Use1 PF09753.9 GBG77421.1 - 0.61 9.8 14.0 2.5 7.8 14.2 1.8 1 1 1 2 2 2 0 Membrane fusion protein Use1 XRCC4 PF06632.12 GBG77421.1 - 0.67 8.7 11.0 0.024 13.5 2.7 2.0 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Spc24 PF08286.11 GBG77421.1 - 1.2 9.4 9.3 0.23 11.7 1.4 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TMPIT PF07851.13 GBG77421.1 - 2.8 7.1 5.9 0.97 8.6 0.3 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 GBG77421.1 - 4.9 6.4 16.8 2.5 7.4 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FUSC PF04632.12 GBG77421.1 - 6.4 5.2 19.0 7.8 4.9 19.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family VIT1 PF01988.19 GBG77422.1 - 3.3e-49 167.7 0.2 3.7e-49 167.5 0.2 1.0 1 0 0 1 1 1 1 VIT family EcoEI_R_C PF08463.10 GBG77422.1 - 0.035 14.2 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 EcoEI R protein C-terminal NADHdeh_related PF10125.9 GBG77422.1 - 0.035 13.5 2.9 0.045 13.1 2.9 1.1 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein DivIC PF04977.15 GBG77422.1 - 0.16 11.7 1.0 6 6.7 0.8 2.3 1 1 0 2 2 2 0 Septum formation initiator Peptidase_M23 PF01551.22 GBG77424.1 - 2.2e-33 114.3 0.4 6.4e-33 112.8 0.3 1.9 2 0 0 2 2 2 1 Peptidase family M23 LysM PF01476.20 GBG77424.1 - 1.1e-18 67.0 0.0 7.9e-09 35.4 0.0 3.1 3 0 0 3 3 3 2 LysM domain RVT_1 PF00078.27 GBG77425.1 - 1.3e-26 93.5 0.0 1.9e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77425.1 - 7.9e-22 77.2 0.0 1.8e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77425.1 - 1.9e-11 44.2 0.0 3.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG77425.1 - 0.011 14.8 0.3 0.032 13.3 0.3 1.5 1 1 1 2 2 2 0 Autophagy protein Apg17 RVT_1 PF00078.27 GBG77426.1 - 1.7e-28 99.6 0.1 2.8e-28 98.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG77426.1 - 1.4e-10 40.9 0.0 3.8e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG77427.1 - 2.2e-30 105.0 0.0 4.6e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77427.1 - 2.6e-29 101.2 0.0 5.6e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77427.1 - 3.4e-16 59.1 2.8 8e-16 57.9 2.8 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77427.1 - 6.7e-11 42.1 0.1 1.3e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG77427.1 - 2.3e-10 40.7 0.1 7.5e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG77427.1 - 0.00033 20.8 0.3 0.0012 19.0 0.3 2.1 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG77428.1 - 4.2e-26 91.3 0.2 1.1e-25 89.9 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77428.1 - 1.4e-18 66.8 0.3 2.7e-18 65.8 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG77428.1 - 1.7e-18 66.5 0.0 5.1e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77428.1 - 1.6e-16 60.5 0.0 4.7e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG77428.1 - 0.0012 19.0 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG77428.1 - 0.039 13.6 0.3 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) AAA_15 PF13175.6 GBG77429.1 - 0.19 11.4 3.8 0.27 10.9 3.8 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF1682 PF07946.14 GBG77429.1 - 0.42 9.8 14.0 0.73 9.0 14.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Histone PF00125.24 GBG77430.1 - 3.8e-21 75.8 0.4 7.3e-21 74.9 0.4 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-CCHC PF00098.23 GBG77431.1 - 5.8e-07 29.3 5.4 1.1e-06 28.5 5.4 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF2514 PF10721.9 GBG77431.1 - 0.079 13.0 9.5 0.16 11.9 9.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) MDM31_MDM32 PF08118.11 GBG77431.1 - 0.69 8.5 2.5 1.1 7.8 2.5 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Protocadherin PF08374.11 GBG77431.1 - 0.78 9.7 3.9 1.5 8.8 3.9 1.4 1 0 0 1 1 1 0 Protocadherin DUF1682 PF07946.14 GBG77431.1 - 1.6 7.9 21.4 2.7 7.1 21.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NARP1 PF12569.8 GBG77431.1 - 2.4 6.9 14.3 3.6 6.4 14.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TMEM214 PF10151.9 GBG77431.1 - 3.5 6.0 7.0 4.9 5.5 7.0 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Presenilin PF01080.17 GBG77431.1 - 3.8 6.2 4.9 5.2 5.7 4.9 1.3 1 0 0 1 1 1 0 Presenilin DUF4337 PF14235.6 GBG77431.1 - 9.7 6.3 8.4 18 5.4 8.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Myb_DNA-bind_4 PF13837.6 GBG77432.1 - 4.9e-05 23.6 2.1 5.6e-05 23.4 1.1 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG77432.1 - 0.06 13.4 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Ribosomal_S21e PF01249.18 GBG77432.1 - 0.16 12.1 0.2 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S21e ECH_1 PF00378.20 GBG77433.1 - 3.1e-19 69.3 0.0 4.8e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 GBG77433.1 - 1.1e-13 51.2 0.0 2.4e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Formyl_trans_N PF00551.19 GBG77433.1 - 7.3e-13 48.6 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Y_phosphatase2 PF03162.13 GBG77434.1 - 1.9e-11 43.8 0.0 2.8e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family RT_RNaseH_2 PF17919.1 GBG77435.1 - 8.9e-27 93.1 0.2 9.1e-24 83.4 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77435.1 - 1e-26 93.9 0.0 1.8e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77435.1 - 7.6e-25 87.2 0.2 8.3e-24 83.9 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG77435.1 - 6.5e-09 35.7 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77435.1 - 5.5e-08 33.3 0.0 1.3e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77435.1 - 3.7e-06 27.4 0.0 9.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG77435.1 - 1.2e-05 25.5 0.1 6.6e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG77435.1 - 0.00025 20.9 0.0 0.0007 19.4 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG77435.1 - 0.0036 17.1 0.0 0.0093 15.8 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease DUF2730 PF10805.8 GBG77435.1 - 0.027 14.6 0.3 0.083 13.0 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SlyX PF04102.12 GBG77435.1 - 0.046 14.3 0.6 0.046 14.3 0.6 4.9 4 1 1 5 5 4 0 SlyX DUF16 PF01519.16 GBG77435.1 - 0.093 13.2 1.0 0.34 11.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 AMP-binding_C_2 PF14535.6 GBG77435.1 - 0.099 13.0 0.0 0.43 10.9 0.0 2.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Chromo PF00385.24 GBG77435.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PTS_IIA PF02255.16 GBG77435.1 - 3 8.0 9.1 0.61 10.2 2.2 3.1 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit DDRGK PF09756.9 GBG77435.1 - 6.4 6.3 10.0 17 5.0 10.0 1.6 1 0 0 1 1 1 0 DDRGK domain Y_phosphatase2 PF03162.13 GBG77436.1 - 3e-45 153.8 0.0 3.7e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GBG77436.1 - 3.3e-08 33.8 0.0 3.5e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GBG77436.1 - 0.0011 18.6 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 GBG77436.1 - 0.0011 18.7 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Nop14 PF04147.12 GBG77437.1 - 0.26 9.5 28.2 0.36 9.0 28.2 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG77437.1 - 0.41 9.9 29.9 0.55 9.5 29.9 1.2 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 GBG77437.1 - 1 9.6 14.5 1.7 8.9 14.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 GBG77437.1 - 1.5 8.2 30.1 2.4 7.5 30.1 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG77437.1 - 6.1 5.0 24.8 7.9 4.6 24.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4360 PF14273.6 GBG77438.1 - 5.1e-43 147.0 0.1 5.8e-43 146.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pox_Ag35 PF03286.14 GBG77439.1 - 7.9e-05 22.5 9.0 7.9e-05 22.5 9.0 2.3 2 0 0 2 2 2 1 Pox virus Ag35 surface protein PTPRCAP PF15713.5 GBG77439.1 - 0.0014 18.9 31.8 0.049 13.9 2.7 2.8 2 0 0 2 2 2 2 Protein tyrosine phosphatase receptor type C-associated RPN2_C PF18004.1 GBG77439.1 - 0.0055 16.6 10.4 0.0055 16.6 10.4 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 GBG77439.1 - 0.0059 16.0 14.0 0.0059 16.0 14.0 2.2 2 0 0 2 2 2 1 BUD22 CCDC53 PF10152.9 GBG77439.1 - 0.016 15.6 6.0 0.78 10.1 5.1 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ribosomal_60s PF00428.19 GBG77439.1 - 0.025 15.2 2.1 0.025 15.2 2.1 3.6 2 1 0 2 2 1 0 60s Acidic ribosomal protein DDHD PF02862.17 GBG77439.1 - 0.041 14.1 2.3 0.057 13.6 1.1 1.8 2 0 0 2 2 2 0 DDHD domain Prothymosin PF03247.14 GBG77439.1 - 0.052 14.0 45.8 0.15 12.6 30.1 2.8 2 0 0 2 2 2 0 Prothymosin/parathymosin family Myc_N PF01056.18 GBG77439.1 - 0.069 13.0 20.2 0.11 12.3 0.1 2.5 2 0 0 2 2 2 0 Myc amino-terminal region DUF2052 PF09747.9 GBG77439.1 - 0.075 13.2 27.5 0.1 12.7 16.6 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SpoIIP PF07454.11 GBG77439.1 - 0.24 10.8 10.8 0.18 11.3 7.6 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Mpp10 PF04006.12 GBG77439.1 - 0.78 8.1 27.0 0.095 11.1 17.2 2.1 2 0 0 2 2 2 0 Mpp10 protein DUF5523 PF17661.1 GBG77439.1 - 0.78 9.4 25.8 0.74 9.5 19.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SDA1 PF05285.12 GBG77439.1 - 0.93 8.9 30.3 0.072 12.5 17.9 2.2 2 0 0 2 2 2 0 SDA1 FYDLN_acid PF09538.10 GBG77439.1 - 1 10.1 25.5 3.8 8.2 18.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RR_TM4-6 PF06459.12 GBG77439.1 - 1.7 8.4 20.2 1.1 9.1 14.9 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BSP_II PF05432.11 GBG77439.1 - 2.4 7.8 34.9 0.099 12.3 17.0 2.6 3 0 0 3 3 2 0 Bone sialoprotein II (BSP-II) Plasmodium_Vir PF05795.11 GBG77439.1 - 2.4 7.5 6.9 0.27 10.6 2.2 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Eapp_C PF10238.9 GBG77439.1 - 2.7 8.1 11.0 1.6 8.8 7.2 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Presenilin PF01080.17 GBG77439.1 - 3 6.5 12.4 0.23 10.2 6.5 1.9 2 0 0 2 2 2 0 Presenilin DUF913 PF06025.12 GBG77439.1 - 3.1 6.7 10.6 2.6 7.0 6.9 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF4628 PF15429.6 GBG77439.1 - 3.4 7.3 13.0 2.2 7.9 6.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) RPA43_OB PF17875.1 GBG77439.1 - 3.6 8.2 12.9 4.5 7.9 6.8 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Vfa1 PF08432.10 GBG77439.1 - 3.7 7.8 17.9 5.8 7.2 13.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Hid1 PF12722.7 GBG77439.1 - 3.7 5.5 5.4 6.3 4.8 5.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 GBG77439.1 - 4.4 6.4 8.5 0.55 9.4 4.3 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter DARPP-32 PF05395.12 GBG77439.1 - 4.5 7.5 26.4 16 5.7 19.3 2.7 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 DUF4820 PF16091.5 GBG77439.1 - 4.8 6.5 18.1 1.2 8.4 12.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CPSF100_C PF13299.6 GBG77439.1 - 5.1 7.3 15.4 2.7 8.1 9.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 GBG77439.1 - 5.7 7.4 13.6 1.5 9.2 8.1 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 MRNIP PF15749.5 GBG77439.1 - 7.6 7.3 15.1 7.2 7.4 11.1 2.3 2 0 0 2 2 2 0 MRN-interacting protein DUF4471 PF14740.6 GBG77439.1 - 7.8 5.6 9.6 1.9 7.6 5.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) PPL5 PF18168.1 GBG77439.1 - 8 5.7 10.8 1.2 8.3 6.7 1.7 2 0 0 2 2 2 0 Prim-pol family 5 DUF1995 PF09353.10 GBG77440.1 - 5.6e-35 121.2 0.0 8.7e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DHC_N1 PF08385.12 GBG77441.1 - 1e-188 628.5 15.9 1e-188 628.5 15.9 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 GBG77441.1 - 2.3e-130 434.4 0.0 1.6e-129 431.6 0.0 2.6 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 GBG77441.1 - 2.3e-123 412.2 12.7 2.3e-123 412.2 12.7 4.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 GBG77441.1 - 2.8e-92 308.7 0.1 1.6e-91 306.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 GBG77441.1 - 2.2e-86 289.9 0.1 2.2e-86 289.9 0.1 3.0 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 GBG77441.1 - 2.1e-82 275.5 1.5 2.1e-82 275.5 1.5 3.9 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 GBG77441.1 - 1.1e-63 214.1 0.1 3.4e-58 196.1 0.0 4.1 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 GBG77441.1 - 5.1e-52 176.0 0.0 1.4e-51 174.5 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 GBG77441.1 - 1.9e-49 168.5 13.6 5.8e-49 167.0 13.6 1.9 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 GBG77441.1 - 9.2e-42 141.9 0.0 2.7e-39 133.9 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 GBG77441.1 - 1.9e-25 89.4 2.7 1.3e-23 83.5 0.0 4.0 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 GBG77441.1 - 9.6e-20 71.0 0.0 5.3e-08 33.0 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 GBG77441.1 - 1.4e-17 63.8 0.8 7.6e-15 55.0 0.0 3.8 2 1 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 GBG77441.1 - 2.2e-11 44.3 0.1 0.0033 17.8 0.0 5.2 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG77441.1 - 0.00029 21.1 2.4 4.9 7.4 0.1 5.4 5 0 0 5 5 4 1 AAA domain Mg_chelatase PF01078.21 GBG77441.1 - 0.00086 18.7 0.1 0.0073 15.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MIX PF18529.1 GBG77441.1 - 0.025 14.3 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial membrane-anchored proteins AAA_18 PF13238.6 GBG77441.1 - 0.027 15.0 2.6 5.3 7.6 0.0 4.0 4 0 0 4 4 2 0 AAA domain T2SSE PF00437.20 GBG77441.1 - 0.031 13.4 0.2 12 4.8 0.0 3.3 3 0 0 3 3 3 0 Type II/IV secretion system protein RNA_helicase PF00910.22 GBG77441.1 - 0.16 12.3 0.5 20 5.6 0.0 3.5 3 0 0 3 3 3 0 RNA helicase Pkinase PF00069.25 GBG77442.1 - 3.1e-49 167.7 0.0 7e-49 166.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG77442.1 - 1e-42 146.2 0.0 1.8e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG77442.1 - 0.0013 18.7 5.7 0.0079 16.1 0.4 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family GAGA_bind PF06217.12 GBG77442.1 - 0.28 11.4 8.9 0.55 10.5 8.9 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family CitMHS PF03600.16 GBG77444.1 - 4e-23 82.1 2.7 5.1e-23 81.7 2.7 1.2 1 0 0 1 1 1 1 Citrate transporter RT_RNaseH_2 PF17919.1 GBG77444.1 - 1.9e-19 69.5 0.0 3.5e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TrkA_C PF02080.21 GBG77444.1 - 7.4e-13 48.1 0.4 8.1e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 TrkA-C domain RT_RNaseH PF17917.1 GBG77444.1 - 1.2e-10 41.7 0.0 2.9e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Na_sulph_symp PF00939.19 GBG77444.1 - 3.6e-05 23.0 8.8 0.017 14.2 1.2 2.1 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region Oleosin PF01277.17 GBG77445.1 - 3.8e-08 33.1 11.2 1.7e-07 31.0 11.2 1.9 1 1 0 1 1 1 1 Oleosin DUF883 PF05957.13 GBG77445.1 - 0.17 12.5 0.6 6 7.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Oleosin PF01277.17 GBG77446.1 - 1e-07 31.7 10.3 4.2e-07 29.7 10.3 1.9 1 1 0 1 1 1 1 Oleosin DUF418 PF04235.12 GBG77446.1 - 0.15 12.0 7.6 0.8 9.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF418) PRIMA1 PF16101.5 GBG77447.1 - 2.2 8.3 7.5 5.2 7.1 7.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RT_RNaseH_2 PF17919.1 GBG77448.1 - 1.2e-27 95.8 0.0 2.1e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77448.1 - 1.6e-23 83.0 0.0 2.9e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77448.1 - 9.7e-06 25.2 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG77448.1 - 0.086 12.3 10.5 0.11 11.8 10.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG77448.1 - 0.14 10.4 9.1 0.21 9.9 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG77448.1 - 0.28 11.2 13.0 0.46 10.6 13.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GBG77448.1 - 0.36 10.5 8.7 0.58 9.9 8.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG77448.1 - 0.39 8.9 12.3 0.5 8.5 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG77448.1 - 1.3 9.3 13.6 2.7 8.3 13.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SIR4_SID PF16991.5 GBG77448.1 - 7.5 6.6 6.7 13 5.8 6.7 1.3 1 0 0 1 1 1 0 Sir4 SID domain Ammonium_transp PF00909.21 GBG77449.1 - 1e-105 353.8 21.6 1.2e-105 353.5 21.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Complex1_LYR_2 PF13233.6 GBG77450.1 - 4.9e-08 33.6 0.3 6.4e-08 33.2 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like XPC-binding PF09280.11 GBG77451.1 - 0.11 12.2 0.5 2.3 8.0 0.1 2.6 2 0 0 2 2 2 0 XPC-binding domain VirDNA-topo-I_N PF09266.10 GBG77451.1 - 0.22 11.7 0.0 0.46 10.7 0.0 1.4 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal SecE PF00584.20 GBG77452.1 - 5.5e-15 55.0 0.5 6.4e-15 54.8 0.5 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Plavaka PF18759.1 GBG77453.1 - 5.3e-10 39.0 0.0 1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase Histone PF00125.24 GBG77453.1 - 2.8e-07 30.9 0.1 6.3e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.24 GBG77455.1 - 9.6e-20 71.3 0.0 1.8e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 IBN_N PF03810.19 GBG77457.1 - 1.6e-10 40.7 0.0 6.4e-10 38.8 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GBG77457.1 - 0.00015 21.8 0.0 0.42 10.7 0.0 3.3 2 1 1 3 3 3 2 Exportin 1-like protein HEAT_EZ PF13513.6 GBG77457.1 - 0.065 13.8 15.2 1.5 9.4 0.3 6.5 6 0 0 6 6 6 0 HEAT-like repeat HEAT PF02985.22 GBG77457.1 - 0.14 12.4 4.6 5.1 7.6 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat RT_RNaseH PF17917.1 GBG77458.1 - 4.5e-35 120.1 6.2 1.1e-20 73.9 0.4 4.0 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77458.1 - 1.4e-33 114.9 0.0 2.6e-19 69.1 0.0 3.3 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77458.1 - 1.2e-23 83.8 0.0 2.5e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OST-HTH PF12872.7 GBG77458.1 - 2.5e-10 40.0 0.1 6.1e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Torus PF16131.5 GBG77458.1 - 1.5e-05 25.7 0.3 1.5e-05 25.7 0.3 3.9 3 1 1 4 4 1 1 Torus domain zf_CCCH_4 PF18345.1 GBG77458.1 - 2.1e-05 24.4 7.2 4.5e-05 23.3 7.2 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GBG77458.1 - 2.5e-05 24.1 6.2 5.3e-05 23.0 6.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GBG77458.1 - 0.00036 20.3 6.3 0.00075 19.2 6.3 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger RskA PF10099.9 GBG77458.1 - 0.0015 18.8 18.3 0.013 15.8 7.4 2.6 2 0 0 2 2 2 2 Anti-sigma-K factor rskA RVP_2 PF08284.11 GBG77458.1 - 0.0043 16.8 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Mitofilin PF09731.9 GBG77458.1 - 0.0091 14.9 23.2 0.05 12.4 4.7 2.2 2 0 0 2 2 2 2 Mitochondrial inner membrane protein DUF4834 PF16118.5 GBG77458.1 - 0.012 16.5 8.1 0.012 16.5 8.1 4.7 3 1 0 3 3 2 0 Domain of unknown function (DUF4834) DUF4746 PF15928.5 GBG77458.1 - 0.028 13.8 16.6 0.11 11.9 8.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Caldesmon PF02029.15 GBG77458.1 - 0.041 12.7 28.8 0.27 10.0 5.7 2.5 3 0 0 3 3 3 0 Caldesmon Nha1_C PF08619.10 GBG77458.1 - 0.088 12.0 32.2 0.11 11.7 14.4 2.3 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus BAF1_ABF1 PF04684.13 GBG77458.1 - 0.092 11.8 27.9 0.024 13.7 8.7 2.8 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 GBG77458.1 - 0.22 10.3 35.6 1.1 8.0 12.7 2.2 2 0 0 2 2 2 0 Presenilin Macoilin PF09726.9 GBG77458.1 - 2.4 6.6 31.0 0.044 12.3 11.5 2.3 2 0 0 2 2 2 0 Macoilin family Dapper PF15268.6 GBG77458.1 - 3 6.6 37.6 0.19 10.5 12.6 2.3 2 0 0 2 2 2 0 Dapper MscS_TM PF12794.7 GBG77458.1 - 3.9 6.2 11.8 13 4.5 11.8 1.9 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Mpp10 PF04006.12 GBG77458.1 - 5.2 5.4 37.9 1.5 7.1 11.8 2.2 2 0 0 2 2 2 0 Mpp10 protein Lin-8 PF03353.15 GBG77458.1 - 6 6.3 37.4 6.5 6.2 17.0 2.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF659 PF04937.15 GBG77459.1 - 3.5e-20 72.4 0.0 2.4e-19 69.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Tho2 PF11262.8 GBG77459.1 - 0.062 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 zf-BED PF02892.15 GBG77459.1 - 0.1 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C3HC4_2 PF13923.6 GBG77460.1 - 5.3e-11 42.2 10.8 1.1e-10 41.1 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG77460.1 - 6.8e-10 38.7 11.5 1.4e-09 37.6 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG77460.1 - 1.8e-09 37.7 9.7 4.5e-09 36.5 9.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 GBG77460.1 - 2.6e-09 37.1 10.4 7e-09 35.7 10.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 GBG77460.1 - 3.8e-09 36.3 8.6 8.4e-09 35.2 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG77460.1 - 4.3e-09 36.2 6.0 5.9e-09 35.8 2.9 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG77460.1 - 1.2e-06 28.4 9.3 2.6e-06 27.3 9.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG77460.1 - 0.00011 22.0 7.9 0.00028 20.7 7.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GBG77460.1 - 0.00012 22.1 6.6 0.00026 21.1 6.6 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 GBG77460.1 - 0.00037 20.7 8.2 0.0041 17.4 8.2 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 GBG77460.1 - 0.00068 19.4 6.1 0.0015 18.3 6.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 GBG77460.1 - 0.0018 18.1 4.2 0.0049 16.7 4.2 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 GBG77460.1 - 0.041 13.7 8.1 0.14 11.9 8.1 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 GBG77460.1 - 0.19 11.5 10.1 0.46 10.3 6.9 2.7 2 0 0 2 2 2 0 RING-like zinc finger zf-P11 PF03854.14 GBG77460.1 - 0.6 9.8 4.2 1.3 8.7 4.2 1.6 1 0 0 1 1 1 0 P-11 zinc finger RT_RNaseH_2 PF17919.1 GBG77462.1 - 2.2e-33 114.3 0.1 4.9e-33 113.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77462.1 - 6.6e-29 100.3 0.1 1.6e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Presenilin PF01080.17 GBG77464.1 - 1.2 7.8 6.5 1.7 7.3 6.5 1.3 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GBG77464.1 - 3.3 6.9 30.3 4.6 6.5 0.1 2.1 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 GBG77464.1 - 8.3 4.6 21.2 13 4.0 21.2 1.2 1 0 0 1 1 1 0 CDC45-like protein O-FucT PF10250.9 GBG77465.1 - 1.3e-40 140.1 0.0 1.9e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PurA PF04845.13 GBG77466.1 - 0.0069 15.7 0.0 2 7.7 0.0 2.0 2 0 0 2 2 2 2 PurA ssDNA and RNA-binding protein Abhydrolase_1 PF00561.20 GBG77467.1 - 6.5e-12 45.6 0.0 1e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG77467.1 - 1.5e-07 32.2 0.1 1.5e-06 29.0 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 GBG77467.1 - 0.0028 17.8 0.0 0.014 15.5 0.0 2.1 3 0 0 3 3 3 1 TAP-like protein FAM176 PF14851.6 GBG77467.1 - 0.081 12.6 3.2 0.17 11.6 3.2 1.5 1 0 0 1 1 1 0 FAM176 family DUF2615 PF11027.8 GBG77467.1 - 0.11 12.7 1.6 0.19 11.9 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DNA_pol_phi PF04931.13 GBG77467.1 - 0.2 9.7 23.8 0.31 9.1 23.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 GBG77467.1 - 0.21 9.7 0.8 0.31 9.1 0.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CobT PF06213.12 GBG77467.1 - 0.67 9.3 11.5 1.2 8.5 11.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 GBG77467.1 - 0.83 8.8 9.0 1.2 8.2 9.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 GBG77467.1 - 3.7 5.7 12.8 5.6 5.1 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG77467.1 - 4.8 6.5 14.6 8.4 5.7 14.6 1.3 1 0 0 1 1 1 0 SDA1 Pkinase_Tyr PF07714.17 GBG77470.1 - 3.8e-33 114.9 0.0 1.8e-32 112.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77470.1 - 9.8e-31 107.1 0.0 2.3e-30 105.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG77472.1 - 1.1e-12 47.9 0.0 1.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77472.1 - 2.9e-11 43.6 0.0 5.7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG77472.1 - 0.052 13.6 1.9 0.094 12.8 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Pkinase_Tyr PF07714.17 GBG77473.1 - 3.8e-38 131.3 0.0 1.9e-37 129.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77473.1 - 2.3e-33 115.7 0.0 3.8e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF659 PF04937.15 GBG77474.1 - 2.2e-14 53.6 0.0 3.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3385 PF11865.8 GBG77478.1 - 3.7e-26 92.0 0.8 1.9e-24 86.4 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) HEAT PF02985.22 GBG77478.1 - 2.8e-10 39.5 6.4 0.069 13.4 0.1 8.3 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 GBG77478.1 - 1.2e-09 38.5 0.3 1.6 9.1 0.0 6.9 6 0 0 6 6 6 3 HEAT repeats Cnd1 PF12717.7 GBG77478.1 - 3.2e-09 37.0 3.6 0.00011 22.3 0.1 5.9 8 0 0 8 8 8 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 GBG77478.1 - 0.00037 20.3 3.0 1.2 9.1 0.1 5.1 5 1 1 6 6 6 1 UME (NUC010) domain HEAT_EZ PF13513.6 GBG77478.1 - 0.0024 18.3 11.0 2.2 8.9 0.1 7.4 8 0 0 8 8 8 1 HEAT-like repeat ParcG PF10274.9 GBG77478.1 - 0.0048 17.0 0.5 15 5.7 0.0 4.3 4 1 0 4 4 4 1 Parkin co-regulated protein Adaptin_N PF01602.20 GBG77478.1 - 0.026 13.1 0.0 0.85 8.1 0.0 3.3 2 1 0 3 3 3 0 Adaptin N terminal region DUF3385 PF11865.8 GBG77479.1 - 3.3e-26 92.1 0.9 1.8e-24 86.5 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) HEAT PF02985.22 GBG77479.1 - 1.9e-10 40.1 6.5 0.065 13.5 0.1 8.4 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 GBG77479.1 - 1.2e-09 38.4 1.3 1.5 9.2 0.0 6.9 7 0 0 7 7 7 3 HEAT repeats Cnd1 PF12717.7 GBG77479.1 - 2.2e-09 37.6 3.5 0.0001 22.4 0.1 5.9 8 0 0 8 8 8 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 GBG77479.1 - 0.00023 21.0 2.7 1.1 9.2 0.1 5.2 5 1 1 6 6 6 1 UME (NUC010) domain HEAT_EZ PF13513.6 GBG77479.1 - 0.0015 19.0 10.8 2.1 9.0 0.1 7.5 8 0 0 8 8 8 1 HEAT-like repeat ParcG PF10274.9 GBG77479.1 - 0.004 17.3 0.6 14 5.7 0.0 4.4 4 1 0 4 4 4 1 Parkin co-regulated protein DUF3437 PF11919.8 GBG77479.1 - 0.011 15.6 0.4 22 5.1 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Adaptin_N PF01602.20 GBG77479.1 - 0.021 13.4 0.0 0.8 8.2 0.0 3.4 2 1 0 3 3 3 0 Adaptin N terminal region HEAT PF02985.22 GBG77480.1 - 8.5e-11 41.2 5.2 0.04 14.2 0.1 7.8 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 GBG77480.1 - 9.5e-11 42.0 0.6 5.7e-05 23.2 0.1 5.3 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GBG77480.1 - 5.6e-10 39.5 0.1 0.91 10.0 0.0 5.9 6 1 0 6 6 6 3 HEAT repeats DUF3385 PF11865.8 GBG77480.1 - 1.7e-08 34.6 2.2 5.3e-07 29.7 0.0 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 GBG77480.1 - 3.8e-05 24.1 5.6 1.2 9.7 0.0 6.1 6 0 0 6 6 6 1 HEAT-like repeat ParcG PF10274.9 GBG77480.1 - 0.03 14.5 0.1 7.9 6.6 0.0 2.9 2 1 0 2 2 2 0 Parkin co-regulated protein Adaptin_N PF01602.20 GBG77480.1 - 0.042 12.4 0.3 0.47 9.0 0.0 2.7 3 2 1 4 4 4 0 Adaptin N terminal region DUF659 PF04937.15 GBG77481.1 - 4.6e-19 68.8 0.0 7.5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ATP_bind_3 PF01171.20 GBG77481.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 PP-loop family HLH PF00010.26 GBG77486.1 - 4.2e-10 39.4 0.1 4.2e-10 39.4 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain gag-asp_proteas PF13975.6 GBG77487.1 - 1e-08 35.6 0.0 2.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77487.1 - 3.2e-06 27.7 0.0 7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG77487.1 - 0.00064 19.5 0.4 0.0014 18.4 0.1 1.6 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG77487.1 - 0.026 14.8 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG77488.1 - 0.0035 17.6 4.7 0.0099 16.1 0.1 3.2 2 1 0 2 2 2 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG77488.1 - 0.017 15.7 2.6 0.017 15.7 2.6 3.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FliD_N PF02465.18 GBG77488.1 - 0.55 11.0 4.8 0.13 13.0 0.6 2.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Scaffolding_pro PF11418.8 GBG77488.1 - 1.2 9.8 4.5 7.4 7.2 0.1 2.7 3 0 0 3 3 3 0 Phi29 scaffolding protein zf-CCHC PF00098.23 GBG77489.1 - 6.3e-07 29.2 0.4 1.7e-06 27.9 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG77489.1 - 0.0038 17.0 1.2 0.0085 15.9 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Borrelia_P83 PF05262.11 GBG77489.1 - 2.9 6.3 13.0 3.2 6.1 13.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Cas_Csx8 PF09657.10 GBG77490.1 - 0.021 13.9 0.1 0.032 13.2 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) RT_RNaseH PF17917.1 GBG77491.1 - 3.6e-28 97.9 0.1 1.4e-27 96.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77491.1 - 5e-27 93.9 0.0 1.9e-26 92.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77491.1 - 5.7e-09 36.0 1.2 1.8e-08 34.3 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77491.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_10 PF05971.12 GBG77492.1 - 1.2e-67 228.3 1.3 3e-28 99.0 0.4 4.2 3 1 0 3 3 3 3 RNA methyltransferase Methyltransf_12 PF08242.12 GBG77492.1 - 0.0037 18.0 0.0 0.0092 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG77492.1 - 0.0046 16.5 0.0 0.65 9.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 GBG77492.1 - 0.018 15.7 0.0 0.14 12.9 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 GBG77492.1 - 0.031 14.9 0.7 0.41 11.3 0.0 3.3 5 0 0 5 5 5 0 Methyltransferase domain Methyltransf_31 PF13847.6 GBG77492.1 - 0.14 11.9 0.0 0.59 9.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 GBG77492.1 - 0.22 10.9 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FbpC_C_terminal PF17845.1 GBG77493.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain SDA1 PF05285.12 GBG77493.1 - 0.05 13.0 81.9 0.18 11.2 10.0 5.1 4 0 0 4 4 4 0 SDA1 FbpC_C_terminal PF17845.1 GBG77494.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain SDA1 PF05285.12 GBG77494.1 - 0.047 13.1 81.9 0.17 11.3 10.0 5.1 4 0 0 4 4 4 0 SDA1 FbpC_C_terminal PF17845.1 GBG77495.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain SDA1 PF05285.12 GBG77495.1 - 0.05 13.0 81.9 0.18 11.2 10.0 5.1 4 0 0 4 4 4 0 SDA1 PsbP PF01789.16 GBG77496.1 - 2.9e-15 56.7 1.4 3.5e-15 56.5 0.5 1.5 2 0 0 2 2 2 1 PsbP GIY-YIG PF01541.24 GBG77497.1 - 1.2e-06 28.7 0.1 1.2e-06 28.7 0.1 2.9 2 1 1 3 3 3 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG77497.1 - 0.00011 22.1 1.3 0.00026 20.9 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG77497.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4238 PF14022.6 GBG77497.1 - 0.038 13.5 0.8 0.15 11.5 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DUF4192 PF13830.6 GBG77497.1 - 1.5 8.8 3.7 3.5 7.6 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) BT1 PF03092.16 GBG77497.1 - 3.6 5.7 8.3 5.7 5.0 8.3 1.2 1 0 0 1 1 1 0 BT1 family Glycoprotein_G PF00802.19 GBG77497.1 - 7.8 5.8 11.8 1.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G AAA_2 PF07724.14 GBG77498.1 - 1.1e-43 149.4 0.0 1.6e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 GBG77498.1 - 1.4e-14 54.7 0.0 2.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GBG77498.1 - 3.2e-14 52.7 0.1 6.3e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GBG77498.1 - 3.9e-05 23.7 0.0 9.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 GBG77498.1 - 0.0002 20.6 0.1 0.00032 19.9 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 GBG77498.1 - 0.00022 21.5 0.1 0.00078 19.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GBG77498.1 - 0.00032 20.5 0.3 0.0014 18.4 0.1 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 GBG77498.1 - 0.00068 19.1 0.0 0.026 13.9 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 GBG77498.1 - 0.0026 17.5 0.0 0.022 14.5 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 GBG77498.1 - 0.0026 17.9 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 GBG77498.1 - 0.008 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 GBG77498.1 - 0.016 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 GBG77498.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 GBG77498.1 - 0.017 15.6 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 GBG77498.1 - 0.039 13.7 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 GBG77498.1 - 0.044 14.2 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 GBG77498.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GBG77498.1 - 0.087 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GBG77498.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GBG77498.1 - 0.17 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 GBG77498.1 - 0.17 11.6 0.1 0.82 9.4 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 GBG77498.1 - 0.19 12.1 0.2 5.8 7.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain polyprenyl_synt PF00348.17 GBG77500.1 - 7.7e-53 179.2 1.7 5.1e-28 97.8 0.0 3.1 1 1 2 3 3 3 3 Polyprenyl synthetase DUF4457 PF14652.6 GBG77500.1 - 0.0021 17.3 0.0 0.81 8.9 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) COX5B PF01215.19 GBG77500.1 - 0.0065 16.2 0.1 2.7 7.7 0.0 2.3 2 0 0 2 2 2 2 Cytochrome c oxidase subunit Vb DUF1989 PF09347.10 GBG77500.1 - 0.18 11.4 0.3 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1989) CDC45 PF02724.14 GBG77500.1 - 3 6.0 8.2 3.9 5.6 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.27 GBG77501.1 - 6.9e-29 101.1 0.0 1.2e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG77501.1 - 6e-07 29.6 0.0 0.0057 16.5 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GBG77501.1 - 0.0001 22.0 0.2 0.00027 20.6 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG77501.1 - 0.019 15.4 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 GBG77501.1 - 0.03 14.1 0.1 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GBG77501.1 - 0.034 14.1 0.1 0.076 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SMC_N PF02463.19 GBG77501.1 - 0.092 12.2 0.1 2.7 7.4 0.1 2.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Cytidylate_kin PF02224.18 GBG77501.1 - 0.11 12.3 0.1 0.31 10.8 0.1 1.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_22 PF13401.6 GBG77501.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GBG77501.1 - 0.11 13.0 0.1 0.37 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GBG77501.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 GBG77501.1 - 0.14 12.6 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GBG77501.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 GBG77501.1 - 0.32 10.7 0.0 2 8.0 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain Glyco_transf_8 PF01501.20 GBG77506.1 - 2.5e-85 286.1 0.3 3.5e-85 285.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GBG77506.1 - 3.7e-05 23.3 0.1 8.4e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 Glucosyltransferase 24 HATPase_c PF02518.26 GBG77507.1 - 8.1e-19 68.2 0.1 5.5e-13 49.4 0.0 3.3 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Presenilin PF01080.17 GBG77508.1 - 5.9 5.6 4.9 5.8 5.6 4.9 1.2 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG77509.1 - 5.1e-30 103.5 0.0 8.2e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77509.1 - 3.1e-27 94.9 0.0 4.8e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77509.1 - 3.2e-13 49.7 0.1 4.6e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG77509.1 - 0.14 12.0 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) ThrE PF06738.12 GBG77511.1 - 4.2e-36 124.5 7.2 4.2e-36 124.5 7.2 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GBG77511.1 - 1.7e-08 34.7 29.7 4.5e-05 23.6 10.7 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF2273 PF10031.9 GBG77511.1 - 0.5 10.4 7.9 5.3 7.1 1.0 2.9 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF1189 PF06691.11 GBG77511.1 - 5.8 6.4 6.8 1.7 8.1 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) ThrE PF06738.12 GBG77512.1 - 3.7e-36 124.7 7.2 3.7e-36 124.7 7.2 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GBG77512.1 - 1.4e-08 34.9 29.7 4.2e-05 23.7 10.7 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF2273 PF10031.9 GBG77512.1 - 0.42 10.7 7.9 5 7.2 1.0 3.0 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF1189 PF06691.11 GBG77512.1 - 4.9 6.6 6.8 1.6 8.2 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) RT_RNaseH_2 PF17919.1 GBG77513.1 - 6.5e-28 96.7 0.0 1.1e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77513.1 - 3.7e-24 85.0 0.0 6.9e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77513.1 - 1.2e-11 44.6 0.1 1.9e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG77513.1 - 0.16 10.1 8.1 0.21 9.8 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG77513.1 - 0.78 8.0 8.7 1 7.6 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG77513.1 - 1.3 8.4 10.1 1.7 8.0 10.1 1.1 1 0 0 1 1 1 0 SDA1 REV PF00424.18 GBG77514.1 - 0.015 15.3 2.2 0.053 13.5 0.1 2.3 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF3629 PF12302.8 GBG77514.1 - 0.33 10.4 15.6 0.012 15.0 7.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3629) FapA PF03961.13 GBG77514.1 - 7 5.1 18.4 1.9 7.0 8.3 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A PIP5K PF01504.18 GBG77516.1 - 1.4e-85 286.8 0.0 3.8e-85 285.5 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MORN PF02493.20 GBG77516.1 - 1.2e-38 128.7 60.6 7.4e-06 25.6 0.5 9.6 9 0 0 9 9 9 8 MORN repeat SF-assemblin PF06705.11 GBG77517.1 - 0.047 13.0 11.7 0.081 12.3 11.7 1.3 1 1 0 1 1 1 0 SF-assemblin/beta giardin Perilipin PF03036.16 GBG77517.1 - 0.13 11.3 6.0 0.14 11.1 5.0 1.5 1 1 0 1 1 1 0 Perilipin family MIF4G_like_2 PF09090.11 GBG77517.1 - 5.9 6.3 11.2 4.2 6.8 10.0 1.3 1 1 0 1 1 1 0 MIF4G like Wtap PF17098.5 GBG77519.1 - 1.2e-37 129.2 10.5 1.2e-37 129.2 10.5 3.6 3 0 0 3 3 3 1 WTAP/Mum2p family TolA_bind_tri PF16331.5 GBG77519.1 - 0.018 15.1 31.8 0.9 9.7 1.6 4.6 4 0 0 4 4 4 0 TolA binding protein trimerisation Seryl_tRNA_N PF02403.22 GBG77519.1 - 0.047 13.9 0.2 0.047 13.9 0.2 6.1 5 2 1 6 6 6 0 Seryl-tRNA synthetase N-terminal domain DUF3452 PF11934.8 GBG77519.1 - 0.7 9.4 5.1 2.9 7.5 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) DASH_Hsk3 PF08227.11 GBG77519.1 - 1.5 9.3 8.6 0.75 10.2 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like NPV_P10 PF05531.12 GBG77519.1 - 2.3 8.8 7.9 8.9 6.9 0.1 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 GBG77519.1 - 9 6.6 7.2 15 5.9 0.2 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4448 PF14610.6 GBG77520.1 - 0.001 18.9 0.0 0.18 11.5 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) MacB_PCD PF12704.7 GBG77520.1 - 0.0012 19.2 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 MacB-like periplasmic core domain Ninjurin PF04923.12 GBG77520.1 - 0.0063 16.4 4.0 0.052 13.5 4.0 2.2 1 1 0 1 1 1 1 Ninjurin Glypican PF01153.19 GBG77520.1 - 0.0092 14.9 2.1 0.01 14.7 2.1 1.2 1 0 0 1 1 1 1 Glypican DUF898 PF05987.13 GBG77520.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF1676 PF07898.13 GBG77520.1 - 0.013 15.6 0.1 0.96 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Orf78 PF06024.12 GBG77520.1 - 0.033 14.5 4.3 1.8 8.9 0.4 2.7 2 1 1 3 3 3 0 Orf78 (ac78) BUD22 PF09073.10 GBG77520.1 - 0.29 10.4 9.5 0.31 10.3 9.5 1.2 1 0 0 1 1 1 0 BUD22 EphA2_TM PF14575.6 GBG77520.1 - 0.48 11.3 0.0 0.48 11.3 0.0 3.4 3 1 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain DUF983 PF06170.12 GBG77520.1 - 0.58 10.6 6.5 3.4 8.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF2615 PF11027.8 GBG77520.1 - 0.82 9.8 12.9 0.76 9.9 0.9 3.0 3 2 0 3 3 3 0 Protein of unknown function (DUF2615) Zip PF02535.22 GBG77520.1 - 2.7 7.1 11.1 3.9 6.6 7.5 2.1 1 1 1 2 2 2 0 ZIP Zinc transporter SelP_N PF04592.14 GBG77520.1 - 5.8 6.2 15.5 2.6 7.4 12.8 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region zinc_ribbon_9 PF14369.6 GBG77521.1 - 9.5e-12 45.0 1.2 9.5e-12 45.0 1.2 2.4 3 0 0 3 3 2 1 zinc-ribbon zf-RING_2 PF13639.6 GBG77521.1 - 1.1e-09 38.4 5.1 1.1e-09 38.4 5.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG77521.1 - 5.6e-08 32.5 5.7 5.6e-08 32.5 5.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG77521.1 - 3.6e-07 29.8 1.4 8.8e-07 28.6 1.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GBG77521.1 - 5.8e-06 26.5 5.8 5.8e-06 26.5 5.8 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GBG77521.1 - 1.2e-05 25.1 4.5 1.2e-05 25.1 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG77521.1 - 0.00013 21.8 10.4 0.00052 19.9 3.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG77521.1 - 0.00031 20.7 1.2 0.00062 19.7 0.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GBG77521.1 - 0.00058 19.7 10.5 0.0012 18.6 3.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 GBG77521.1 - 0.0089 16.0 5.8 0.02 14.9 0.1 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ANAPC11 PF12861.7 GBG77521.1 - 0.011 15.7 1.0 0.03 14.3 1.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 GBG77521.1 - 0.012 15.6 6.4 0.061 13.4 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon Rad50_zn_hook PF04423.14 GBG77521.1 - 0.015 15.1 0.6 7.9 6.4 0.0 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 GBG77521.1 - 0.021 14.7 2.9 0.021 14.7 2.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GBG77521.1 - 0.058 13.5 2.3 0.14 12.3 2.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 DNA_RNApol_7kD PF03604.13 GBG77521.1 - 0.19 11.4 4.2 0.16 11.6 0.9 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.6 GBG77521.1 - 0.22 11.5 9.0 1 9.3 0.2 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 TF_Zn_Ribbon PF08271.12 GBG77521.1 - 1.3 8.6 4.3 2.3 7.8 1.3 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zinc-ribbons_6 PF07191.12 GBG77521.1 - 2.7 8.0 6.7 4.2 7.4 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbons zf-C3H2C3 PF17122.5 GBG77521.1 - 4.8 7.3 10.7 7.4 6.7 3.9 2.6 2 0 0 2 2 2 0 Zinc-finger DUF4164 PF13747.6 GBG77522.1 - 0.005 17.1 41.2 0.042 14.1 0.0 5.7 4 1 1 5 5 5 3 Domain of unknown function (DUF4164) Baculo_PEP_C PF04513.12 GBG77522.1 - 0.11 12.5 0.0 0.11 12.5 0.0 3.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 GBG77525.1 - 0.42 10.8 4.7 1 9.5 4.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CREPT PF16566.5 GBG77525.1 - 0.77 9.9 6.5 1.7 8.8 6.5 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Peptidase_S9 PF00326.21 GBG77526.1 - 2.6e-43 148.0 0.0 4.6e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 GBG77526.1 - 2.8e-07 30.3 4.2 0.0057 16.6 0.1 3.0 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DLH PF01738.18 GBG77526.1 - 0.00031 20.4 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 GBG77526.1 - 0.0034 16.1 0.0 2 7.0 0.0 2.7 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 GBG77526.1 - 0.0044 16.3 0.0 0.011 15.0 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 GBG77526.1 - 0.021 14.4 0.0 0.26 10.8 0.0 2.1 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 GBG77526.1 - 0.021 14.7 0.1 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 GBG77526.1 - 0.031 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) ComK PF06338.11 GBG77526.1 - 0.28 10.8 0.0 1.1 8.9 0.0 1.9 2 0 0 2 2 2 0 ComK protein RT_RNaseH_2 PF17919.1 GBG77527.1 - 3.1e-27 94.5 0.0 4.4e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77527.1 - 9.4e-26 90.1 0.0 1.4e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77528.1 - 3.8e-30 103.9 0.0 8.4e-15 54.6 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77528.1 - 4.4e-29 100.9 0.0 1.1e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77528.1 - 5.2e-28 98.1 0.2 1.5e-27 96.6 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77528.1 - 3e-16 59.3 0.0 1.4e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG77528.1 - 2.9e-05 24.2 0.0 7.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG77529.1 - 2e-05 24.6 0.0 5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG77529.1 - 0.00014 22.3 0.0 0.00031 21.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77529.1 - 0.00029 21.4 0.0 0.0006 20.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG77529.1 - 0.00058 20.1 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77530.1 - 2.9e-23 81.8 0.0 5.7e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77530.1 - 9.3e-20 70.9 0.0 4.7e-19 68.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG77530.1 - 0.082 13.2 0.2 0.53 10.6 0.1 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein rve PF00665.26 GBG77530.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 GBG77530.1 - 0.14 12.8 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG77530.1 - 0.16 11.7 0.0 0.54 10.1 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG77530.1 - 0.21 11.1 0.0 0.52 9.8 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1664 PF07889.12 GBG77530.1 - 1.4 9.0 3.9 2.2 8.3 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Mitofilin PF09731.9 GBG77533.1 - 0.14 10.9 24.1 0.16 10.8 24.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4778 PF16008.5 GBG77533.1 - 0.31 11.1 13.9 0.4 10.7 13.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) SOBP PF15279.6 GBG77533.1 - 0.89 10.1 10.2 1.1 9.8 10.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 GBG77533.1 - 1.3 7.7 18.3 1.5 7.5 18.3 1.2 1 0 0 1 1 1 0 Presenilin Red1 PF07964.11 GBG77533.1 - 1.7 6.8 30.7 2 6.6 30.7 1.2 1 0 0 1 1 1 0 Rec10 / Red1 DUF5523 PF17661.1 GBG77533.1 - 2.9 7.5 31.4 4.3 6.9 31.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Ndc1_Nup PF09531.10 GBG77533.1 - 5.7 5.5 8.3 6.8 5.3 8.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RT_RNaseH_2 PF17919.1 GBG77534.1 - 7.5e-60 199.2 0.0 8.2e-31 106.0 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77534.1 - 2.3e-50 169.2 0.1 2.9e-25 88.6 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77534.1 - 1.9e-39 135.5 0.7 1e-25 90.5 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG77534.1 - 1.8e-05 24.9 15.0 0.0094 16.2 0.1 5.4 5 0 0 5 5 5 2 Retrotransposon gag protein DUF5066 PF16728.5 GBG77534.1 - 0.052 12.9 0.1 0.15 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) rve PF00665.26 GBG77534.1 - 0.11 12.6 0.0 0.53 10.5 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain NIR_SIR PF01077.22 GBG77534.1 - 0.2 11.1 0.5 0.72 9.3 0.4 1.9 2 0 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain Chromo PF00385.24 GBG77534.1 - 0.38 10.7 1.4 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Kelch_1 PF01344.25 GBG77535.1 - 5.6e-16 57.9 25.7 6.1e-05 22.5 0.0 8.2 7 1 0 7 7 7 3 Kelch motif Kelch_6 PF13964.6 GBG77535.1 - 2.1e-11 43.7 3.7 0.053 13.8 0.0 7.0 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 GBG77535.1 - 3.2e-09 36.4 6.9 0.025 14.6 0.0 7.5 8 0 0 8 8 8 1 Kelch motif Myb_DNA-bind_4 PF13837.6 GBG77535.1 - 1.5e-07 31.7 2.0 3.3e-07 30.6 2.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain F-box PF00646.33 GBG77535.1 - 1.7e-07 30.9 2.5 3.8e-07 29.8 2.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG77535.1 - 1.6e-06 27.9 3.5 3.4e-06 26.8 3.5 1.5 1 0 0 1 1 1 1 F-box-like Kelch_5 PF13854.6 GBG77535.1 - 0.0012 18.7 0.2 2.8 8.0 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Myb_DNA-bind_5 PF13873.6 GBG77535.1 - 0.012 15.7 1.2 0.031 14.3 1.2 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77535.1 - 0.02 15.2 0.3 0.059 13.7 0.3 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Kelch_3 PF13415.6 GBG77535.1 - 0.39 11.1 3.0 4.8 7.6 0.0 4.2 5 0 0 5 5 5 0 Galactose oxidase, central domain BTB PF00651.31 GBG77537.1 - 2.1e-25 89.1 0.1 3e-24 85.4 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 GBG77537.1 - 9.7e-05 22.4 0.2 0.0019 18.3 0.1 2.6 1 1 1 2 2 2 1 BTB And C-terminal Kelch MATH PF00917.26 GBG77537.1 - 0.00017 21.7 0.0 0.00096 19.3 0.0 2.1 1 1 0 1 1 1 1 MATH domain NIR_SIR PF01077.22 GBG77538.1 - 5.2e-57 191.8 0.0 4.1e-49 166.1 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 GBG77538.1 - 2.7e-27 94.4 0.0 1e-14 54.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain RT_RNaseH_2 PF17919.1 GBG77539.1 - 2.4e-34 117.3 0.0 1e-33 115.3 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77539.1 - 3.5e-30 104.4 0.2 1.7e-29 102.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77539.1 - 3.1e-24 85.7 0.0 2.2e-23 82.9 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77539.1 - 5e-17 61.8 0.4 1.3e-16 60.4 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG77539.1 - 3.5e-06 27.2 7.1 0.039 14.2 0.0 4.7 4 1 0 4 4 4 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG77539.1 - 5.3e-06 26.2 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG77539.1 - 6.9e-05 23.2 1.8 0.00026 21.3 1.8 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Succ_CoA_lig PF13607.6 GBG77539.1 - 0.026 14.3 0.9 0.38 10.6 0.1 2.4 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Asp_protease_2 PF13650.6 GBG77539.1 - 0.032 14.9 0.0 0.099 13.3 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Myb_DNA-binding PF00249.31 GBG77539.1 - 0.072 13.3 0.2 0.47 10.7 0.5 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain gag-asp_proteas PF13975.6 GBG77539.1 - 0.08 13.5 0.0 0.27 11.8 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease AIP3 PF03915.13 GBG77539.1 - 0.088 11.9 5.6 0.23 10.5 5.6 1.6 1 0 0 1 1 1 0 Actin interacting protein 3 LPP PF04728.13 GBG77539.1 - 4 7.9 5.8 26 5.3 0.2 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DDE_Tnp_4 PF13359.6 GBG77540.1 - 4.2e-21 75.2 0.0 9.4e-21 74.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77540.1 - 5.9e-14 52.1 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Paramyxo_C PF01692.18 GBG77540.1 - 0.26 10.6 0.9 8.3 5.7 0.1 2.3 2 0 0 2 2 2 0 Paramyxovirus non-structural protein C GST_N_5 PF18485.1 GBG77541.1 - 7 7.1 10.5 5.7 7.4 0.4 3.3 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain EMP24_GP25L PF01105.24 GBG77542.1 - 7.7e-37 127.0 0.1 9.7e-37 126.7 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RT_RNaseH PF17917.1 GBG77543.1 - 4.8e-19 68.6 0.2 1.1e-18 67.4 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77543.1 - 1e-13 51.5 0.0 3.2e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG77543.1 - 5.5e-11 42.4 0.0 1.4e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG77543.1 - 0.014 15.1 0.2 0.048 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) FAM199X PF15814.5 GBG77543.1 - 3.5 6.6 9.2 6.5 5.7 9.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X DUF659 PF04937.15 GBG77545.1 - 7.1e-37 126.6 0.0 1.3e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) BAF1_ABF1 PF04684.13 GBG77545.1 - 9.6 5.1 9.6 12 4.8 9.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ydr279_N PF17745.1 GBG77546.1 - 7.7e-05 22.9 0.0 9.1e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain LRR_4 PF12799.7 GBG77547.1 - 8.2e-11 42.0 7.3 0.45 11.0 0.0 8.7 5 2 5 10 10 10 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG77547.1 - 4.8e-09 35.5 16.0 0.27 11.4 0.0 10.1 11 0 0 11 11 11 3 Leucine Rich repeat F-box-like PF12937.7 GBG77547.1 - 5.7e-07 29.3 1.5 1.7e-06 27.8 0.6 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GBG77547.1 - 2.7e-05 23.9 0.3 0.00014 21.7 0.3 2.3 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 GBG77547.1 - 0.21 11.4 13.8 0.55 10.0 0.5 6.2 6 2 2 8 8 8 0 Leucine rich repeat BAR PF03114.18 GBG77548.1 - 0.015 15.0 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 BAR domain DTHCT PF08070.11 GBG77548.1 - 0.3 11.8 1.5 1.6 9.5 0.8 2.1 1 1 1 2 2 2 0 DTHCT (NUC029) region Adeno_terminal PF02459.15 GBG77549.1 - 0.081 11.3 5.9 0.11 10.9 5.9 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein gag-asp_proteas PF13975.6 GBG77550.1 - 3e-10 40.5 0.0 1.7e-09 38.1 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77550.1 - 5.7e-09 35.8 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG77550.1 - 2.7e-07 31.2 0.0 1.1e-06 29.2 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG77550.1 - 0.0012 19.1 1.6 0.0018 18.5 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG77550.1 - 0.012 15.7 1.2 0.024 14.7 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1805 PF08827.11 GBG77550.1 - 0.22 11.9 0.9 44 4.5 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) Ribosomal_60s PF00428.19 GBG77550.1 - 0.4 11.3 7.0 0.36 11.4 2.7 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cas_APE2256 PF09651.10 GBG77550.1 - 0.97 9.3 2.9 4.2 7.3 0.1 2.7 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_APE2256) RT_RNaseH_2 PF17919.1 GBG77551.1 - 4.8e-65 215.9 0.0 9.9e-33 112.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77551.1 - 6.1e-59 196.8 0.3 1e-29 102.9 0.1 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77551.1 - 1.2e-38 132.9 0.2 1.5e-26 93.3 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77551.1 - 6.8e-18 64.5 0.1 1.5e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77551.1 - 1e-14 54.7 0.3 3.6e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Acyltransferase PF01553.21 GBG77551.1 - 0.00053 19.6 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase zf-H2C2 PF09337.10 GBG77551.1 - 0.15 12.3 0.0 0.56 10.5 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Zip PF02535.22 GBG77551.1 - 0.74 9.0 2.2 1.2 8.3 2.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter O-antigen_lig PF13425.6 GBG77551.1 - 2.2 7.0 5.5 3.6 6.3 5.5 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Connexin PF00029.19 GBG77551.1 - 7.4 6.2 6.6 16 5.2 6.6 1.5 1 0 0 1 1 1 0 Connexin Integrase_H2C2 PF17921.1 GBG77553.1 - 1.1e-17 63.9 0.4 2e-17 63.0 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77553.1 - 1.2e-10 41.6 0.0 3.6e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG77553.1 - 7.8e-07 28.8 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPAP1_N PF08621.10 GBG77553.1 - 0.03 14.1 2.9 6.5 6.6 0.2 3.0 2 0 0 2 2 2 0 RPAP1-like, N-terminal Retrotrans_gag PF03732.17 GBG77553.1 - 0.05 13.9 0.0 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4939 PF16297.5 GBG77553.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Snapin_Pallidin PF14712.6 GBG77553.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.8 1 1 0 2 2 2 0 Snapin/Pallidin Phycobilisome PF00502.19 GBG77553.1 - 0.71 9.8 2.9 11 5.9 0.0 2.6 2 1 0 2 2 2 0 Phycobilisome protein eIF3_subunit PF08597.10 GBG77553.1 - 1.2 9.0 6.2 2.2 8.1 6.2 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit EzrA PF06160.12 GBG77553.1 - 1.6 6.8 7.2 2.5 6.2 6.6 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Mito_fiss_reg PF05308.11 GBG77553.1 - 3.2 7.8 16.9 1.1 9.3 8.6 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Flagellin_C PF00700.21 GBG77553.1 - 6.1 7.3 7.4 0.54 10.6 0.2 2.4 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region RVT_1 PF00078.27 GBG77554.1 - 0.0036 16.9 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG77555.1 - 9.5e-32 110.3 0.1 5e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77555.1 - 1.6e-31 108.3 0.0 4.1e-31 107.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77555.1 - 1.7e-29 102.2 0.1 5e-29 100.7 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG77555.1 - 3.6e-09 37.2 0.0 0.0014 19.3 0.0 3.7 4 0 0 4 4 3 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG77555.1 - 3.6e-09 37.1 0.0 0.0019 18.7 0.0 3.0 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77555.1 - 5.2e-08 32.8 0.0 5.1e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG77555.1 - 1.6e-05 24.7 0.0 0.012 15.4 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease DUF1758 PF05585.12 GBG77555.1 - 0.0077 16.0 0.0 0.037 13.8 0.0 2.0 2 0 0 2 2 2 1 Putative peptidase (DUF1758) DUF848 PF05852.11 GBG77555.1 - 0.063 13.4 6.4 0.4 10.8 0.4 2.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DivIC PF04977.15 GBG77555.1 - 2.3 8.0 10.0 2 8.3 0.8 3.5 3 0 0 3 3 3 0 Septum formation initiator HALZ PF02183.18 GBG77555.1 - 7.3 6.9 6.0 3.6 7.9 0.5 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper QIL1 PF15884.5 GBG77556.1 - 0.047 14.3 0.0 0.061 13.9 0.0 1.2 1 0 0 1 1 1 0 MICOS complex subunit MIC13, QIL1 RT_RNaseH PF17917.1 GBG77557.1 - 2.5e-22 79.2 0.0 5.8e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77557.1 - 1.4e-21 76.3 0.0 2.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77557.1 - 7.1e-17 61.7 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG77557.1 - 1e-12 47.9 0.4 2.4e-12 46.7 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77557.1 - 0.0032 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG77557.1 - 0.053 13.8 0.6 0.13 12.5 0.6 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 GBG77557.1 - 0.16 11.8 0.0 0.47 10.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RNase_T PF00929.24 GBG77558.1 - 2.2e-11 44.6 0.0 4.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease NOA36 PF06524.12 GBG77558.1 - 1.5 8.1 4.7 3.1 7.0 4.7 1.5 1 0 0 1 1 1 0 NOA36 protein DUF3754 PF12576.8 GBG77559.1 - 1.6e-20 73.4 0.0 3.1e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) RVT_1 PF00078.27 GBG77561.1 - 1e-26 93.8 0.0 1.8e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG77561.1 - 3.6e-06 27.6 1.4 1.6e-05 25.5 1.4 2.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-UBP_var PF17807.1 GBG77565.1 - 0.069 12.9 0.0 5.3 6.9 0.1 2.6 2 1 0 2 2 2 0 Variant UBP zinc finger PGA2 PF07543.12 GBG77565.1 - 0.33 10.9 5.1 0.71 9.8 5.1 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 RVT_1 PF00078.27 GBG77566.1 - 1.4e-37 129.4 0.0 2.1e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) G10 PF01125.17 GBG77566.1 - 0.034 13.9 1.2 0.045 13.5 0.1 1.7 2 0 0 2 2 2 0 G10 protein zf-RVT PF13966.6 GBG77568.1 - 0.00057 20.6 5.8 0.00057 20.6 5.8 3.0 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 GBG77568.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Corazonin PF17308.2 GBG77571.1 - 0.12 12.7 12.1 2.4 8.5 4.8 2.5 2 0 0 2 2 2 0 Pro-corazonin YlbD_coat PF14071.6 GBG77571.1 - 0.52 10.6 4.2 0.55 10.5 2.0 2.1 2 0 0 2 2 2 0 Putative coat protein RVT_1 PF00078.27 GBG77572.1 - 5.5e-20 71.8 0.0 1e-18 67.7 0.0 2.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Biotin_carb_C PF02785.19 GBG77573.1 - 0.076 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain ubiquitin PF00240.23 GBG77575.1 - 3e-19 68.5 0.0 3e-19 68.5 0.0 2.1 2 0 0 2 2 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 GBG77575.1 - 1.1e-05 25.8 0.0 1.1e-05 25.8 0.0 2.0 2 0 0 2 2 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 GBG77575.1 - 5.6e-05 22.9 0.0 5.6e-05 22.9 0.0 2.3 2 1 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 GBG77575.1 - 0.0026 17.9 0.0 0.0026 17.9 0.0 2.8 2 1 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like NigD_C PF17415.2 GBG77575.1 - 0.086 12.9 2.4 0.55 10.3 0.3 2.2 1 1 1 2 2 2 0 NigD-like C-terminal beta sandwich domain DUF2407 PF10302.9 GBG77575.1 - 0.16 12.5 0.1 0.16 12.5 0.1 3.3 3 1 0 3 3 1 0 DUF2407 ubiquitin-like domain DDHD PF02862.17 GBG77575.1 - 0.31 11.2 12.6 0.32 11.1 7.9 2.5 2 0 0 2 2 2 0 DDHD domain Connexin PF00029.19 GBG77575.1 - 0.7 9.6 13.1 0.06 13.1 8.0 1.7 2 0 0 2 2 2 0 Connexin HCO3_cotransp PF00955.21 GBG77575.1 - 1.3 7.7 3.0 2.5 6.8 3.0 1.3 1 0 0 1 1 1 0 HCO3- transporter family LMBR1 PF04791.16 GBG77575.1 - 1.4 7.7 6.5 2.1 7.2 6.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3520 PF12034.8 GBG77575.1 - 2.3 8.3 7.8 4.6 7.3 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3520) EOS1 PF12326.8 GBG77575.1 - 2.8 7.8 4.9 0.92 9.4 1.5 1.8 2 0 0 2 2 2 0 N-glycosylation protein SpoIIP PF07454.11 GBG77575.1 - 5.9 6.3 13.1 0.95 8.9 6.8 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Adaptin_N PF01602.20 GBG77576.1 - 9.4e-132 440.2 9.8 1.1e-131 439.9 9.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 GBG77576.1 - 9.6e-57 191.4 0.5 2.8e-56 189.9 0.1 2.0 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 GBG77576.1 - 3.5e-34 117.4 0.0 7.3e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 GBG77576.1 - 3e-16 59.6 3.5 6.4e-08 32.9 0.0 6.0 2 1 5 7 7 7 3 HEAT repeats Cnd1 PF12717.7 GBG77576.1 - 1.4e-10 41.5 14.9 1.3e-05 25.3 0.4 4.5 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GBG77576.1 - 2.2e-05 24.8 5.0 0.044 14.3 0.2 4.0 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 GBG77576.1 - 0.00023 21.1 6.7 10 6.7 0.1 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_PBS PF03130.16 GBG77576.1 - 0.006 17.1 0.8 0.44 11.4 0.1 3.9 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Arm PF00514.23 GBG77576.1 - 0.15 12.1 0.1 16 5.7 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF659 PF04937.15 GBG77577.1 - 1.4e-26 93.2 0.0 2.8e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG77577.1 - 7.1e-11 41.7 0.2 1.7e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Myosin_head PF00063.21 GBG77578.1 - 4.3e-250 831.6 0.2 4.3e-250 831.6 0.2 1.8 2 1 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.19 GBG77578.1 - 6e-25 87.5 0.1 6e-25 87.5 0.1 4.4 4 2 1 5 5 5 1 DIL domain IQ PF00612.27 GBG77578.1 - 1.6e-16 58.5 24.6 4.6e-05 22.9 1.1 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.19 GBG77578.1 - 0.00012 21.8 1.9 0.00024 20.9 1.9 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 GBG77578.1 - 0.075 13.4 0.0 0.075 13.4 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain Cupin_8 PF13621.6 GBG77578.1 - 0.35 10.5 2.9 1.1 9.0 2.7 2.0 1 1 0 1 1 1 0 Cupin-like domain AAA_19 PF13245.6 GBG77578.1 - 0.47 10.8 0.0 0.47 10.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 GBG77578.1 - 1.5 9.1 7.8 0.95 9.7 0.1 3.8 4 0 0 4 4 4 0 AAA domain GAS PF13851.6 GBG77578.1 - 3.2 7.0 53.9 0.03 13.7 22.3 3.6 1 1 2 3 3 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 GBG77578.1 - 4.6 7.9 39.9 0.61 10.8 6.0 4.9 1 1 3 4 4 4 0 Initiation control protein YabA FtsK_SpoIIIE PF01580.18 GBG77578.1 - 6.5 6.0 8.6 3.9 6.7 0.0 3.3 2 1 1 3 3 3 0 FtsK/SpoIIIE family UPF0242 PF06785.11 GBG77578.1 - 8.7 6.4 50.4 0.53 10.4 16.1 3.6 1 1 1 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus PALP PF00291.25 GBG77579.1 - 7.3e-31 107.7 0.0 1.3e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme OKR_DC_1_N PF03709.15 GBG77579.1 - 0.04 14.2 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain RVT_1 PF00078.27 GBG77580.1 - 2.9e-28 98.9 0.2 5.5e-28 98.0 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77580.1 - 3.2e-06 27.1 0.0 9.1e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glu-tRNAGln PF02686.15 GBG77580.1 - 0.13 12.6 0.5 12 6.3 0.0 3.3 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit CobU PF02283.16 GBG77580.1 - 2.9 7.4 4.3 5.7 6.5 0.7 2.0 1 1 1 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RT_RNaseH_2 PF17919.1 GBG77582.1 - 1.1e-21 76.8 0.0 3.6e-21 75.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77582.1 - 9.1e-21 74.1 0.0 3.1e-20 72.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77582.1 - 5.6e-15 55.5 0.7 8.6e-12 45.0 0.2 2.7 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG77582.1 - 0.0015 18.7 4.5 0.0027 17.9 0.2 3.4 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG77582.1 - 0.0031 17.3 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease TFIIA PF03153.13 GBG77582.1 - 1 9.3 12.0 1.5 8.7 12.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CREPT PF16566.5 GBG77582.1 - 2.2 8.5 8.2 11 6.2 2.3 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SpoIIIAH PF12685.7 GBG77582.1 - 3.8 7.3 12.3 6 6.6 12.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein PALP PF00291.25 GBG77583.1 - 3.2e-11 43.2 0.0 5.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RVT_1 PF00078.27 GBG77585.1 - 5.5e-26 91.4 0.1 1.9e-25 89.7 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG77585.1 - 5e-10 39.6 0.0 2.3e-09 37.5 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG77585.1 - 2e-09 37.7 0.1 6.5e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG77585.1 - 6.2e-05 23.6 0.0 0.00018 22.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77585.1 - 0.00016 22.1 0.0 0.00056 20.4 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77585.1 - 0.00038 20.2 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease HIP1_clath_bdg PF16515.5 GBG77585.1 - 0.0035 17.9 3.8 0.0035 17.9 3.8 3.3 4 0 0 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 RT_RNaseH_2 PF17919.1 GBG77585.1 - 0.014 15.5 0.0 0.044 13.8 0.0 1.9 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG77585.1 - 0.041 13.7 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Senescence_reg PF04520.13 GBG77585.1 - 0.057 14.3 2.7 0.33 11.8 2.7 2.4 1 0 0 1 1 1 0 Senescence regulator Asp_protease_2 PF13650.6 GBG77587.1 - 0.00047 20.8 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77587.1 - 0.00051 20.5 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 GBG77587.1 - 0.00083 19.3 0.4 0.0018 18.2 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF1758 PF05585.12 GBG77587.1 - 0.0048 16.7 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG77587.1 - 0.053 13.3 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC PF00098.23 GBG77587.1 - 0.61 10.3 9.7 0.069 13.3 4.8 2.1 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG77588.1 - 3.2e-26 92.2 0.1 4.7e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77589.1 - 4.2e-61 203.2 0.1 8.1e-32 109.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77589.1 - 1.4e-52 176.4 0.0 5.5e-29 100.5 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77589.1 - 2.1e-32 112.4 0.1 3.7e-32 111.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77589.1 - 3.6e-18 65.4 0.2 7.4e-18 64.4 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77589.1 - 3.8e-14 52.9 0.0 1.9e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG77589.1 - 6.8e-05 23.4 0.0 0.00018 22.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77589.1 - 0.00013 21.7 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG77589.1 - 0.024 14.4 0.1 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG77589.1 - 0.14 12.9 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG77590.1 - 5.8e-17 61.9 0.0 1.5e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77590.1 - 3.4e-14 52.7 0.0 7.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG77590.1 - 2.8e-08 34.2 0.0 6.6e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG77590.1 - 7.5e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG77590.1 - 3.4e-05 24.4 0.0 7.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG77590.1 - 0.0018 18.1 0.1 0.0036 17.1 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG77590.1 - 0.0028 17.9 0.0 0.0079 16.5 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RPW8 PF05659.11 GBG77590.1 - 0.026 14.2 0.5 4.7 6.9 0.2 2.6 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Adeno_terminal PF02459.15 GBG77591.1 - 0.004 15.6 0.3 0.004 15.6 0.3 1.1 1 0 0 1 1 1 1 Adenoviral DNA terminal protein Ribosomal_60s PF00428.19 GBG77591.1 - 0.016 15.8 12.7 0.04 14.5 12.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.18 GBG77591.1 - 0.026 14.4 2.3 0.027 14.4 2.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_L18_c PF14204.6 GBG77591.1 - 0.042 14.8 5.9 0.12 13.3 5.9 1.8 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region RbsD_FucU PF05025.13 GBG77591.1 - 0.047 14.1 2.5 0.11 13.0 2.2 1.7 2 0 0 2 2 2 0 RbsD / FucU transport protein family Retrotrans_gag PF03732.17 GBG77592.1 - 0.0019 18.5 0.3 0.0056 16.9 0.3 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein ETC_C1_NDUFA4 PF04800.12 GBG77594.1 - 0.16 12.3 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 ETC complex I subunit conserved region RRF_GI PF12614.8 GBG77594.1 - 0.59 10.3 7.6 1.9 8.7 2.2 2.3 2 0 0 2 2 2 0 Ribosome recycling factor DUF4407 PF14362.6 GBG77594.1 - 1.4 8.2 8.6 4.3 6.6 8.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RNB PF00773.19 GBG77594.1 - 1.7 7.9 4.3 0.94 8.7 1.7 1.7 1 1 0 2 2 2 0 RNB domain RasGAP_C PF03836.15 GBG77594.1 - 1.9 8.6 13.4 14 5.8 0.4 3.5 3 1 0 3 3 3 0 RasGAP C-terminus DUF1664 PF07889.12 GBG77594.1 - 3.2 7.8 15.8 7.2 6.7 1.0 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 GBG77594.1 - 4.4 7.5 26.0 6.1 7.0 1.3 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 GBG77594.1 - 6.6 7.1 29.7 0.67 10.4 16.8 2.2 1 1 1 2 2 2 0 Fez1 Atg14 PF10186.9 GBG77594.1 - 7.4 5.6 10.6 3.2 6.8 7.9 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CorA PF01544.18 GBG77594.1 - 8.9 5.5 9.6 1.4 8.2 0.3 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Complex1_LYR PF05347.15 GBG77595.1 - 5.8e-06 26.3 0.5 8.4e-06 25.7 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Rota_VP2 PF05087.12 GBG77595.1 - 0.11 10.6 0.0 0.11 10.6 0.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein 4HBT PF03061.22 GBG77596.1 - 1e-08 35.4 0.1 0.0016 18.7 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily DEK_C PF08766.11 GBG77597.1 - 0.011 15.7 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 0 DEK C terminal domain RT_RNaseH_2 PF17919.1 GBG77598.1 - 7.8e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77598.1 - 4.8e-06 26.8 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77598.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SlyX PF04102.12 GBG77598.1 - 0.18 12.4 0.1 0.18 12.4 0.1 3.3 3 0 0 3 3 3 0 SlyX PKcGMP_CC PF16808.5 GBG77598.1 - 1.6 8.6 6.4 4.5 7.2 0.9 3.6 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase gag-asp_proteas PF13975.6 GBG77599.1 - 0.00012 22.5 0.0 0.00034 21.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77599.1 - 0.011 16.3 0.0 0.029 15.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Ribosomal_60s PF00428.19 GBG77599.1 - 0.11 13.1 3.1 0.54 10.9 3.1 2.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein MutS_III PF05192.18 GBG77600.1 - 5.9e-34 118.0 1.4 8.6e-34 117.4 1.4 1.3 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.21 GBG77600.1 - 1.5e-24 87.1 0.2 4.4e-24 85.5 0.2 1.8 2 0 0 2 2 2 1 MutS domain V MutS_IV PF05190.18 GBG77600.1 - 4.5e-18 65.4 2.7 1.2e-17 64.0 2.7 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 GBG77600.1 - 5.1e-13 49.3 0.0 1.1e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain I AAA_15 PF13175.6 GBG77600.1 - 0.0011 18.7 1.7 0.0015 18.4 0.6 1.8 2 0 0 2 2 2 1 AAA ATPase domain CAMP_factor PF07373.11 GBG77600.1 - 0.22 11.1 2.6 3 7.4 0.1 2.5 2 1 0 2 2 2 0 CAMP factor (Cfa) GTP1_OBG PF01018.22 GBG77601.1 - 8.1e-52 174.9 9.9 1.9e-51 173.7 9.9 1.7 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 GBG77601.1 - 4.9e-23 81.4 0.0 1.5e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1967 PF09269.11 GBG77601.1 - 6.4e-13 48.4 0.1 1.4e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) FeoB_N PF02421.18 GBG77601.1 - 3.6e-08 33.1 0.0 7.5e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 GBG77601.1 - 0.0036 16.3 0.1 1.7 7.5 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 GBG77601.1 - 0.16 12.5 0.0 0.16 12.5 0.0 2.5 2 1 0 2 2 2 0 ABC transporter zf-CCHC PF00098.23 GBG77602.1 - 8.3e-06 25.6 2.8 1.8e-05 24.6 2.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG77602.1 - 0.023 14.4 0.9 0.051 13.3 0.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG77602.1 - 0.32 10.9 2.9 0.7 9.8 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle C2 PF00168.30 GBG77603.1 - 5.6e-15 55.5 0.0 1.2e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain MMM1 PF10296.9 GBG77603.1 - 4.3e-05 22.7 0.0 0.029 13.4 0.0 2.3 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 SMP_LBD PF17047.5 GBG77603.1 - 0.00024 20.6 0.1 0.00039 19.9 0.1 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain DOCK-C2 PF14429.6 GBG77603.1 - 0.055 13.3 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins DnaJ PF00226.31 GBG77604.1 - 2.7e-19 69.1 0.1 8.6e-19 67.4 0.1 1.8 1 1 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 GBG77604.1 - 1.2e-13 50.3 10.1 0.00016 21.3 0.1 7.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG77604.1 - 1.2e-09 37.5 19.3 0.025 14.7 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 GBG77604.1 - 3.9e-06 27.3 9.1 0.011 16.2 0.0 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG77604.1 - 0.00029 21.4 19.4 2.5 9.1 0.0 7.6 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG77604.1 - 0.00033 20.9 8.8 0.93 9.8 0.4 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG77604.1 - 0.0048 16.6 9.8 1.7 8.4 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_6 PF13174.6 GBG77604.1 - 0.074 13.7 1.1 17 6.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG77604.1 - 0.13 12.4 9.2 7.5 6.8 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG77604.1 - 0.14 12.6 0.4 49 4.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG77604.1 - 0.45 10.9 9.6 5.9 7.4 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG77604.1 - 3 7.8 11.6 26 4.9 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG77604.1 - 6.2 7.0 16.0 0.63 10.2 0.7 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-CCCH PF00642.24 GBG77605.1 - 5.5e-47 156.9 46.5 1.3e-09 37.7 5.3 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG77605.1 - 3.5e-18 65.0 59.8 3.6e-05 23.7 6.7 5.4 5 0 0 5 5 5 5 Zinc finger domain zf-CCCH_4 PF18044.1 GBG77605.1 - 3.5e-14 52.2 48.2 0.00079 19.2 4.7 5.3 5 0 0 5 5 5 5 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GBG77605.1 - 8.5e-11 41.9 48.2 0.025 15.1 4.0 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GBG77605.1 - 5.6e-07 30.2 21.4 0.69 10.6 0.4 5.3 5 0 0 5 5 5 5 Torus domain DUF4129 PF13559.6 GBG77605.1 - 0.1 12.9 0.7 4 7.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) zf-CCCH_3 PF15663.5 GBG77605.1 - 0.28 11.4 21.6 3.4 7.9 0.8 5.1 5 0 0 5 5 5 0 Zinc-finger containing family zf-CCCH PF00642.24 GBG77606.1 - 4e-47 157.3 46.5 1.2e-09 37.8 5.3 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG77606.1 - 2.8e-18 65.3 59.8 3.3e-05 23.8 6.7 5.3 5 0 0 5 5 5 5 Zinc finger domain zf-CCCH_4 PF18044.1 GBG77606.1 - 2.5e-14 52.7 48.2 0.00074 19.3 4.7 5.3 5 0 0 5 5 5 5 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GBG77606.1 - 6.1e-11 42.4 48.2 0.023 15.2 4.0 5.3 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GBG77606.1 - 9.3e-08 32.7 19.1 0.64 10.7 0.4 5.2 5 0 0 5 5 5 5 Torus domain zf-CCCH_3 PF15663.5 GBG77606.1 - 0.046 13.9 19.3 2.5 8.3 0.2 5.1 5 0 0 5 5 5 0 Zinc-finger containing family DUF4129 PF13559.6 GBG77606.1 - 0.083 13.2 0.7 3.6 7.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) DUF2012 PF09430.10 GBG77607.1 - 1.6e-22 79.9 0.2 2.2e-22 79.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 GBG77607.1 - 0.0017 18.0 0.2 0.0057 16.2 0.1 1.8 2 0 0 2 2 2 1 Suppressor of PMA 1-7 protein CarboxypepD_reg PF13620.6 GBG77607.1 - 0.071 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 GBG77607.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 CarboxypepD_reg-like domain DUF5134 PF17197.4 GBG77607.1 - 0.56 10.1 7.4 2.3 8.1 7.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) RT_RNaseH PF17917.1 GBG77608.1 - 1.4e-19 70.4 0.0 2.8e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77608.1 - 8.6e-18 64.2 0.0 1.6e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77608.1 - 2.9e-11 43.3 0.1 4.2e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77609.1 - 1.8e-39 133.8 0.0 3.3e-25 88.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77609.1 - 1.3e-36 126.3 0.6 7.2e-24 84.5 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77609.1 - 1.8e-27 95.6 0.0 4.3e-24 84.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG77609.1 - 1.3e-07 31.4 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77609.1 - 1.1e-06 29.1 0.0 3e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77609.1 - 2.9e-05 24.5 0.0 7.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG77609.1 - 0.0013 19.0 1.8 0.0044 17.3 0.1 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG77610.1 - 2.4e-25 88.5 0.0 4.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77610.1 - 1.4e-20 73.5 0.0 2.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77610.1 - 2.4e-15 56.6 0.1 3.7e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG77610.1 - 0.0055 16.7 0.3 0.0055 16.7 0.3 1.8 2 0 0 2 2 2 1 Zinc knuckle Lin-8 PF03353.15 GBG77610.1 - 0.36 10.4 16.3 0.54 9.8 16.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG77610.1 - 1 7.5 27.3 1.4 7.0 27.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG77610.1 - 1.4 8.3 28.8 1.9 7.8 28.8 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG77610.1 - 2.8 7.2 29.8 4.3 6.6 29.8 1.2 1 0 0 1 1 1 0 BUD22 DUF2201_N PF13203.6 GBG77610.1 - 4 6.9 8.8 9.2 5.8 8.8 1.6 1 0 0 1 1 1 0 Putative metallopeptidase domain YL1 PF05764.13 GBG77610.1 - 9.2 6.3 28.6 17 5.4 28.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 GBG77610.1 - 9.5 4.4 22.5 14 3.8 22.5 1.2 1 0 0 1 1 1 0 CDC45-like protein PRIMA1 PF16101.5 GBG77611.1 - 0.025 14.6 3.7 0.054 13.5 3.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 GBG77611.1 - 2.7 8.0 6.2 2.1 8.3 0.9 2.6 3 0 0 3 3 3 0 Mitochondrial fission regulator RT_RNaseH_2 PF17919.1 GBG77613.1 - 1.9e-25 88.8 0.0 4.4e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77613.1 - 1.5e-23 83.1 0.0 3.1e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77613.1 - 1.9e-15 57.0 0.0 3.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG77613.1 - 8.1e-09 35.2 1.5 2.5e-08 33.6 1.5 1.9 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG77613.1 - 1.2e-05 25.7 0.0 2.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG77613.1 - 0.00026 20.8 2.0 0.00075 19.3 2.0 1.9 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG77613.1 - 0.00037 21.1 0.0 0.0008 20.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG77614.1 - 1.4e-27 96.6 0.0 2.4e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG77614.1 - 1.1e-11 44.4 0.0 2.6e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG77614.1 - 5.5e-08 33.0 0.0 1.8e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain CDC45 PF02724.14 GBG77615.1 - 0.36 9.1 10.4 0.46 8.7 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG77615.1 - 1 7.9 14.4 1.3 7.5 14.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ferlin_C PF16165.5 GBG77615.1 - 2.5 8.0 4.8 0.76 9.7 1.5 1.8 2 0 0 2 2 2 0 Ferlin C-terminus Nop14 PF04147.12 GBG77615.1 - 5.6 5.0 13.6 7.6 4.6 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family Hydrolase_6 PF13344.6 GBG77616.1 - 2.3e-21 75.8 0.0 3.7e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Trehalase PF01204.18 GBG77617.1 - 3.5e-144 481.4 0.0 1.2e-97 327.9 0.0 2.0 2 0 0 2 2 2 2 Trehalase Caudo_TAP PF02413.17 GBG77619.1 - 0.17 12.1 9.3 0.5 10.5 9.3 1.8 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Borrelia_P83 PF05262.11 GBG77619.1 - 0.53 8.7 14.9 0.66 8.4 14.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RE_AlwI PF09491.10 GBG77619.1 - 1.4 7.6 7.7 2.5 6.8 7.7 1.3 1 0 0 1 1 1 0 AlwI restriction endonuclease Mt_ATP-synt_B PF05405.14 GBG77619.1 - 3.2 7.3 10.9 1.7 8.2 8.3 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TP53IP5 PF15331.6 GBG77619.1 - 4 7.5 14.0 7 6.7 14.0 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Connexin PF00029.19 GBG77619.1 - 8.1 6.1 7.4 53 3.5 8.0 2.0 2 0 0 2 2 2 0 Connexin Presenilin PF01080.17 GBG77619.1 - 9.1 4.9 10.2 13 4.4 10.2 1.2 1 0 0 1 1 1 0 Presenilin CAF1C_H4-bd PF12265.8 GBG77620.1 - 7.4e-30 103.0 0.1 5.6e-29 100.2 0.2 2.5 4 0 0 4 4 4 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GBG77620.1 - 6.7e-25 86.9 3.4 0.00027 21.7 0.3 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG77620.1 - 6e-06 26.5 0.3 0.025 14.8 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG77620.1 - 0.00055 19.9 0.4 0.22 11.4 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 GBG77621.1 - 2.5e-160 534.4 0.0 6.9e-160 532.9 0.0 1.7 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 GBG77621.1 - 1.1e-37 127.4 9.1 3.5e-07 30.8 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Clathrin PF00637.20 GBG77621.1 - 0.0075 16.1 0.1 0.018 14.9 0.1 1.7 2 0 0 2 2 2 1 Region in Clathrin and VPS Nup160 PF11715.8 GBG77621.1 - 0.067 11.8 2.2 13 4.3 0.1 3.5 3 1 1 4 4 4 0 Nucleoporin Nup120/160 CiPC PF15800.5 GBG77622.1 - 7.8 6.1 14.3 8 6.1 14.3 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian RT_RNaseH PF17917.1 GBG77624.1 - 2.1e-28 98.7 0.1 4.8e-28 97.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77624.1 - 5.4e-28 97.0 0.2 2.1e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77624.1 - 1.4e-13 50.7 0.2 4.4e-13 49.1 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Rhomboid PF01694.22 GBG77624.1 - 1.1e-12 48.2 5.1 2.2e-12 47.2 5.1 1.5 1 0 0 1 1 1 1 Rhomboid family RVT_1 PF00078.27 GBG77624.1 - 1.9e-10 40.6 0.1 3.9e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG77624.1 - 0.058 13.1 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) CKAP2_C PF15297.6 GBG77625.1 - 0.12 11.5 0.2 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus RVT_1 PF00078.27 GBG77626.1 - 1.9e-25 89.7 0.0 3.8e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77626.1 - 1e-23 83.2 0.0 2.3e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77626.1 - 7.7e-19 67.9 0.0 1.8e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77626.1 - 4.1e-17 62.0 0.2 4.1e-17 62.0 0.2 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG77626.1 - 1.5e-08 34.8 0.0 4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG77626.1 - 0.00027 21.1 0.0 0.0017 18.6 0.0 2.4 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.24 GBG77626.1 - 0.0063 16.4 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain WD40 PF00400.32 GBG77627.1 - 3.8e-59 195.3 25.3 3.1e-09 37.3 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG77627.1 - 1.1e-16 60.8 0.0 0.015 15.6 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG77627.1 - 8.3e-05 21.7 3.2 0.2 10.6 0.0 4.5 2 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GBG77627.1 - 0.011 14.4 2.8 18 3.8 0.0 4.3 3 2 2 5 5 5 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 GBG77627.1 - 0.15 11.8 0.6 10 5.9 0.1 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Myb_DNA-bind_4 PF13837.6 GBG77628.1 - 1.6e-07 31.6 0.4 1.6e-07 31.6 0.4 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77628.1 - 0.0017 18.6 0.1 0.0049 17.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like NAM-associated PF14303.6 GBG77628.1 - 0.14 12.8 0.3 0.14 12.8 0.3 2.6 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain Myb_DNA-bind_5 PF13873.6 GBG77628.1 - 5.2 7.2 9.6 0.14 12.2 1.4 2.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG77629.1 - 8.4e-31 106.8 0.0 1.6e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77629.1 - 9.1e-15 54.8 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77629.1 - 0.026 14.2 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain DUF1223 PF06764.11 GBG77631.1 - 1.6e-55 188.3 0.2 1.6e-55 188.3 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1223) PhoD PF09423.10 GBG77632.1 - 1.5e-08 34.1 0.0 4.4e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase DUF4705 PF15788.5 GBG77632.1 - 0.028 14.6 0.5 0.028 14.6 0.5 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4705) VWA_3_C PF18571.1 GBG77632.1 - 0.2 11.6 0.1 13 5.7 0.0 2.5 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain Homoserine_dh PF00742.19 GBG77634.1 - 2.6e-48 164.2 0.0 7.3e-48 162.7 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 GBG77634.1 - 1.6e-09 38.4 1.3 5.2e-08 33.6 1.3 2.4 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GBG77634.1 - 0.017 15.4 2.1 0.17 12.1 2.1 2.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_S8 PF00082.22 GBG77635.1 - 1.9e-43 148.9 1.3 3.5e-35 121.7 0.2 2.9 3 0 0 3 3 3 2 Subtilase family BUD22 PF09073.10 GBG77637.1 - 7.5 5.8 23.4 8.8 5.5 23.4 1.2 1 0 0 1 1 1 0 BUD22 zf-CCCH PF00642.24 GBG77638.1 - 1.6e-13 50.2 8.5 2.5e-09 36.8 0.6 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GBG77638.1 - 2.3e-07 30.5 8.9 6.3e-05 22.7 1.8 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GBG77638.1 - 1.4e-05 24.9 13.6 0.00066 19.7 2.7 2.9 2 0 0 2 2 2 2 Zinc finger domain Exostosin PF03016.15 GBG77638.1 - 0.0096 15.2 0.1 0.019 14.2 0.1 1.4 1 0 0 1 1 1 1 Exostosin family zf-CCCH_2 PF14608.6 GBG77638.1 - 0.2 12.2 9.9 0.3 11.6 0.8 3.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GBG77638.1 - 0.38 11.5 8.6 2.4 8.9 0.8 3.0 1 1 1 2 2 2 0 Torus domain Lustrin_cystein PF14625.6 GBG77638.1 - 0.79 10.1 9.1 0.17 12.3 0.3 3.7 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain E3_UbLigase_R4 PF13764.6 GBG77640.1 - 1.1e-280 933.4 0.0 1.8e-279 929.4 0.0 2.8 3 0 0 3 3 3 1 E3 ubiquitin-protein ligase UBR4 Integrase_H2C2 PF17921.1 GBG77640.1 - 1.6e-18 66.5 0.2 5e-18 65.0 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG77640.1 - 9.6e-17 60.9 0.0 2.1e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77640.1 - 1e-09 38.3 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ZZ PF00569.17 GBG77640.1 - 2.9e-09 36.6 12.7 2.9e-09 36.6 12.7 3.7 3 0 0 3 3 1 1 Zinc finger, ZZ type RT_RNaseH PF17917.1 GBG77640.1 - 2.5e-08 34.2 0.0 8.7e-08 32.4 0.0 1.9 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase PAT1 PF09770.9 GBG77640.1 - 0.029 12.7 6.5 0.052 11.8 6.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 GBG77640.1 - 0.15 12.7 11.4 1.2 9.7 11.9 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Velvet PF11754.8 GBG77640.1 - 0.52 10.2 7.1 1.4 8.8 7.1 1.7 1 0 0 1 1 1 0 Velvet factor Spt20 PF12090.8 GBG77640.1 - 1.3 8.6 21.3 0.89 9.1 19.4 1.6 2 0 0 2 2 2 0 Spt20 family Med15 PF09606.10 GBG77640.1 - 7.6 5.1 23.5 16 4.0 23.5 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CSRNP_N PF16019.5 GBG77641.1 - 0.011 15.7 1.5 0.017 15.0 1.5 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus HAUS6_N PF14661.6 GBG77641.1 - 0.031 13.9 4.7 0.041 13.4 4.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RNA_polI_A34 PF08208.11 GBG77641.1 - 0.035 14.2 16.2 0.047 13.8 16.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.10 GBG77641.1 - 0.07 13.5 11.5 0.094 13.0 11.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 GBG77641.1 - 0.089 12.6 12.4 0.11 12.2 12.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP70 PF00012.20 GBG77641.1 - 0.19 9.8 7.9 0.22 9.6 7.9 1.1 1 0 0 1 1 1 0 Hsp70 protein Borrelia_P83 PF05262.11 GBG77641.1 - 0.2 10.1 12.2 0.2 10.1 12.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Zip PF02535.22 GBG77641.1 - 0.27 10.4 1.5 0.28 10.4 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NARP1 PF12569.8 GBG77641.1 - 0.28 10.1 11.4 0.32 9.8 11.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.17 GBG77641.1 - 0.28 11.3 1.5 0.31 11.2 1.5 1.2 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.16 GBG77641.1 - 0.29 10.6 6.7 0.35 10.3 6.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.6 GBG77641.1 - 0.46 9.8 4.8 0.51 9.6 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MDM10 PF12519.8 GBG77641.1 - 0.93 8.3 5.8 1.2 7.9 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Fmp27 PF10344.9 GBG77641.1 - 1 7.3 8.3 1.3 7.0 8.3 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Connexin PF00029.19 GBG77641.1 - 1.3 8.7 8.1 1.8 8.3 8.1 1.2 1 0 0 1 1 1 0 Connexin DUF4337 PF14235.6 GBG77641.1 - 1.4 9.0 7.7 1.8 8.6 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pinin_SDK_memA PF04696.13 GBG77641.1 - 1.9 8.6 29.8 0.19 11.8 25.2 1.6 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region EMC3_TMCO1 PF01956.16 GBG77641.1 - 2.7 7.7 6.4 3.6 7.3 6.4 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Presenilin PF01080.17 GBG77641.1 - 4.5 5.9 8.9 5.5 5.6 8.9 1.1 1 0 0 1 1 1 0 Presenilin DUF740 PF05340.12 GBG77641.1 - 5.9 5.5 10.6 8.1 5.1 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF4820 PF16091.5 GBG77641.1 - 6.5 6.0 10.7 9.8 5.5 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CAF1 PF04857.20 GBG77641.1 - 7.1 5.7 8.0 10 5.1 8.0 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease PA26 PF04636.13 GBG77641.1 - 7.9 5.3 11.4 9.8 5.0 11.4 1.4 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC45 PF02724.14 GBG77641.1 - 8.6 4.5 11.4 9.3 4.4 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM76 PF16046.5 GBG77643.1 - 0.043 13.2 8.2 0.07 12.5 8.2 1.3 1 0 0 1 1 1 0 FAM76 protein Retrotrans_gag PF03732.17 GBG77643.1 - 2.7 8.3 9.8 0.27 11.5 0.2 3.7 4 1 0 4 4 4 0 Retrotransposon gag protein PspB PF06667.12 GBG77643.1 - 3.3 7.8 9.1 22 5.2 0.2 3.1 3 1 0 3 3 3 0 Phage shock protein B HGTP_anticodon PF03129.20 GBG77644.1 - 5.2e-21 74.6 0.4 2.3e-20 72.5 0.1 2.4 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.20 GBG77644.1 - 4.4e-05 23.5 0.7 0.00018 21.6 0.7 2.1 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 GBG77644.1 - 0.00037 20.5 0.0 0.00078 19.5 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) KASH_CCD PF14662.6 GBG77644.1 - 0.048 13.5 0.1 0.048 13.5 0.1 2.8 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF728 PF05304.12 GBG77644.1 - 0.1 12.4 0.2 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF728) HSP70 PF00012.20 GBG77645.1 - 4.5e-270 897.0 3.3 5.2e-270 896.8 3.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG77645.1 - 7.2e-12 44.8 0.2 2e-09 36.7 0.0 2.9 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG77645.1 - 6.2e-07 29.3 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG77645.1 - 0.026 14.9 2.3 6.4 7.3 0.0 3.8 3 2 0 3 3 3 0 Cell division protein FtsA RNA_pol_Rpb1_6 PF04992.14 GBG77645.1 - 0.11 12.3 0.9 0.2 11.4 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 RNA_pol_Rbc25 PF08292.12 GBG77647.1 - 0.069 13.4 0.6 0.087 13.1 0.6 1.3 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 RT_RNaseH_2 PF17919.1 GBG77648.1 - 2.1e-21 75.8 0.0 4.9e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77648.1 - 4.7e-19 68.6 0.0 1.6e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77648.1 - 5.5e-06 26.6 0.1 2.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG77648.1 - 0.0022 17.9 0.0 0.0052 16.7 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG77648.1 - 0.013 15.3 0.6 0.043 13.6 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) TMEM247 PF15444.6 GBG77648.1 - 0.013 15.5 0.0 0.038 14.0 0.0 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 MAS20 PF02064.15 GBG77648.1 - 0.97 9.5 0.0 0.97 9.5 0.0 4.2 5 0 0 5 5 5 0 MAS20 protein import receptor zf-CCHC_3 PF13917.6 GBG77648.1 - 0.99 9.4 8.0 0.092 12.7 2.7 2.0 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG77649.1 - 1.2e-32 113.2 0.1 1.9e-32 112.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG77650.1 - 5.8e-33 114.3 0.1 1.3e-32 113.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77650.1 - 3.6e-31 107.6 0.1 5.3e-30 103.8 0.1 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77650.1 - 3.9e-29 100.6 0.0 3.2e-28 97.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77650.1 - 2e-17 63.0 1.0 5.3e-17 61.7 1.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77650.1 - 2.8e-17 63.0 0.0 6.7e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG77650.1 - 0.038 14.2 0.0 0.15 12.3 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger NurA PF09376.10 GBG77650.1 - 0.13 11.9 0.1 0.51 10.0 0.1 2.1 2 0 0 2 2 2 0 NurA domain RVT_1 PF00078.27 GBG77651.1 - 1.1e-17 64.3 0.0 6.7e-14 51.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG77651.1 - 5e-06 26.3 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77651.1 - 6e-06 26.8 0.0 1.6e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77651.1 - 7.8e-06 26.4 0.0 2.3e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77651.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease AvrLm4-7 PF18661.1 GBG77651.1 - 0.38 11.8 2.4 30 5.7 1.2 2.8 2 0 0 2 2 2 0 Avirulence Effector AvrLm4-7 Retrotrans_gag PF03732.17 GBG77652.1 - 0.00081 19.6 0.0 0.0034 17.6 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein PBP1_TM PF14812.6 GBG77652.1 - 0.082 13.3 4.3 0.17 12.3 4.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3824 PF12868.7 GBG77652.1 - 1 10.0 5.7 2.1 9.0 5.7 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) zf-primase PF09329.11 GBG77652.1 - 2.6 7.9 4.5 52 3.8 4.5 2.4 1 1 0 1 1 1 0 Primase zinc finger RVT_1 PF00078.27 GBG77653.1 - 2e-30 106.0 0.0 3.3e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PET PF06297.14 GBG77653.1 - 0.11 12.8 1.2 0.48 10.8 0.3 2.5 3 0 0 3 3 3 0 PET Domain PCI PF01399.27 GBG77654.1 - 7.4e-26 90.7 2.8 2.2e-25 89.2 0.9 2.5 2 0 0 2 2 2 1 PCI domain TPR_14 PF13428.6 GBG77654.1 - 0.087 13.7 0.1 4.6 8.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat GAT PF03127.14 GBG77654.1 - 0.29 11.5 5.5 0.61 10.4 0.2 3.8 4 0 0 4 4 4 0 GAT domain TPR_8 PF13181.6 GBG77654.1 - 0.43 10.9 3.8 26 5.4 0.7 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ubie_methyltran PF01209.18 GBG77655.1 - 6.5e-20 71.5 0.0 9.4e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GBG77655.1 - 4.2e-19 69.1 0.1 1.5e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG77655.1 - 3.5e-17 62.8 0.2 3.9e-16 59.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG77655.1 - 1.8e-14 53.8 0.0 3.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG77655.1 - 5.2e-12 46.4 0.4 1.3e-11 45.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GBG77655.1 - 1.3e-06 28.0 0.1 2.8e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 GBG77655.1 - 3e-05 23.7 0.1 0.00012 21.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GBG77655.1 - 0.00085 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 GBG77655.1 - 0.00087 19.1 0.0 0.0071 16.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF938) BSP_II PF05432.11 GBG77655.1 - 0.0014 18.4 8.5 0.0019 18.0 8.5 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Methyltransf_16 PF10294.9 GBG77655.1 - 0.0064 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 GBG77655.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_8 PF05148.15 GBG77655.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_18 PF12847.7 GBG77655.1 - 0.028 14.4 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 GBG77655.1 - 0.047 13.0 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase tRNA_U5-meth_tr PF05958.11 GBG77655.1 - 0.094 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Myc_N PF01056.18 GBG77655.1 - 0.096 12.6 1.0 0.14 12.0 1.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Methyltr_RsmB-F PF01189.17 GBG77655.1 - 0.12 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F CDC45 PF02724.14 GBG77655.1 - 0.14 10.4 0.5 0.19 10.0 0.5 1.1 1 0 0 1 1 1 0 CDC45-like protein BHD_2 PF10404.9 GBG77655.1 - 0.26 12.3 4.1 0.72 10.9 4.1 1.7 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 GRP PF07172.11 GBG77655.1 - 1.4 9.6 13.7 2.4 8.9 13.7 1.3 1 0 0 1 1 1 0 Glycine rich protein family DNA_pol_phi PF04931.13 GBG77655.1 - 5.2 5.0 8.6 7.3 4.5 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP_sp32 PF07222.12 GBG77655.1 - 5.7 6.3 6.7 9.4 5.6 6.7 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RNA_pol_3_Rpc31 PF11705.8 GBG77655.1 - 8.2 6.6 14.0 15 5.8 14.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 GBG77655.1 - 9.8 6.6 10.0 22 5.5 10.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Stevor PF17410.2 GBG77656.1 - 0.03 13.9 6.3 0.044 13.3 6.3 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Menin PF05053.13 GBG77656.1 - 2.6 6.3 10.3 3.2 6.0 10.3 1.2 1 0 0 1 1 1 0 Menin DDE_Tnp_4 PF13359.6 GBG77657.1 - 1.3e-18 67.2 0.0 1.4e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77657.1 - 7.6e-08 32.2 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG77658.1 - 2.4e-07 31.0 3.2 2.8e-07 30.8 1.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77658.1 - 0.062 13.6 0.3 0.17 12.2 0.3 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG77658.1 - 0.21 11.7 2.3 0.59 10.3 2.3 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf_CCCH_4 PF18345.1 GBG77659.1 - 1.3e-05 25.1 18.1 0.032 14.3 2.5 3.7 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 GBG77659.1 - 2.1e-05 25.2 9.1 0.027 15.2 3.3 3.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 GBG77659.1 - 0.00086 19.0 17.4 0.0031 17.3 2.5 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 GBG77659.1 - 0.0053 17.0 2.4 0.016 15.4 2.4 1.8 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 GBG77659.1 - 0.0085 16.5 18.9 0.08 13.4 5.3 3.6 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 GBG77659.1 - 1.6 8.7 13.6 0.69 9.9 2.1 3.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG77660.1 - 1.3e-05 25.1 18.1 0.032 14.3 2.5 3.7 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 GBG77660.1 - 2.1e-05 25.2 9.1 0.028 15.1 3.2 3.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 GBG77660.1 - 0.00087 19.0 17.4 0.0031 17.3 2.5 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 GBG77660.1 - 0.0053 17.0 2.4 0.016 15.4 2.4 1.8 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 GBG77660.1 - 0.0086 16.5 18.9 0.08 13.4 5.3 3.6 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 GBG77660.1 - 1.7 8.7 13.6 0.69 9.9 2.1 3.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sugar_tr PF00083.24 GBG77662.1 - 2.2e-33 115.8 29.0 3.1e-30 105.4 10.9 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GBG77662.1 - 6.5e-17 61.5 46.7 9.1e-12 44.6 22.6 3.3 3 0 0 3 3 3 2 Major Facilitator Superfamily Oleosin PF01277.17 GBG77662.1 - 7.9 6.3 10.0 1.2 8.9 0.5 3.5 3 0 0 3 3 3 0 Oleosin Sugar_tr PF00083.24 GBG77663.1 - 2.3e-33 115.8 29.0 3.2e-30 105.4 10.9 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GBG77663.1 - 5.2e-18 65.1 43.3 9.2e-12 44.5 22.6 3.3 3 0 0 3 3 3 2 Major Facilitator Superfamily Oleosin PF01277.17 GBG77663.1 - 8 6.3 10.0 1.2 8.9 0.5 3.5 3 0 0 3 3 3 0 Oleosin zf-CCHC PF00098.23 GBG77664.1 - 4.2e-06 26.6 3.2 4.2e-06 26.6 3.2 1.7 2 0 0 2 2 2 1 Zinc knuckle RVP_2 PF08284.11 GBG77664.1 - 0.0044 16.8 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG77664.1 - 0.014 15.2 0.2 0.024 14.4 0.2 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG77664.1 - 0.17 11.7 4.6 0.3 11.0 4.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Mei5 PF10376.9 GBG77664.1 - 0.31 10.9 9.0 0.64 9.8 9.0 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein BUD22 PF09073.10 GBG77664.1 - 9.7 5.4 25.9 17 4.6 25.9 1.3 1 0 0 1 1 1 0 BUD22 Myb_DNA-bind_4 PF13837.6 GBG77665.1 - 7.6e-05 23.0 3.2 0.00013 22.3 3.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4551 PF15087.6 GBG77666.1 - 3.9e-09 35.9 1.6 7.9e-05 21.7 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF4551) SGP PF17228.2 GBG77666.1 - 0.04 14.7 12.3 0.045 14.6 8.9 2.4 2 0 0 2 2 2 0 Sulphur globule protein Actin PF00022.19 GBG77667.1 - 1.3e-144 481.8 0.0 4.4e-144 480.1 0.0 1.7 1 1 0 1 1 1 1 Actin Asp_protease_2 PF13650.6 GBG77668.1 - 2.6e-08 34.4 0.0 5.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG77668.1 - 6.3e-08 32.5 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG77668.1 - 4.8e-06 27.1 0.0 1.4e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77668.1 - 0.00084 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG77668.1 - 0.0042 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein VID27 PF08553.10 GBG77669.1 - 2.7e-19 69.4 0.0 1.1e-18 67.4 0.0 1.9 1 1 0 1 1 1 1 VID27 C-terminal WD40-like domain Str_synth PF03088.16 GBG77669.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Strictosidine synthase BNR PF02012.20 GBG77669.1 - 0.93 9.8 3.7 4.3 7.7 0.3 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Actin PF00022.19 GBG77670.1 - 5e-128 427.2 0.0 1.3e-127 425.8 0.0 1.7 1 1 0 1 1 1 1 Actin RVT_1 PF00078.27 GBG77670.1 - 7.9e-36 123.6 0.0 2e-35 122.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) KH_7 PF17214.3 GBG77670.1 - 0.041 13.8 0.0 0.74 9.8 0.0 2.6 2 0 0 2 2 2 0 KH domain MreB_Mbl PF06723.13 GBG77670.1 - 0.08 11.7 0.0 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein AIG1 PF04548.16 GBG77671.1 - 8.8e-19 67.7 0.0 1.8e-18 66.7 0.0 1.5 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GBG77671.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Foie-gras_1 PF11817.8 GBG77674.1 - 1.8e-47 162.2 0.4 2.6e-47 161.6 0.4 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.12 GBG77674.1 - 1.6e-05 23.9 0.1 0.0012 17.7 0.2 2.2 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi TPR_2 PF07719.17 GBG77674.1 - 0.034 14.3 0.4 7.2 7.0 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG77674.1 - 0.97 9.8 2.9 62 4.0 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CCHC PF00098.23 GBG77675.1 - 4.8e-06 26.4 1.7 9.1e-06 25.5 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG77675.1 - 0.0065 16.4 1.2 0.015 15.2 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle D5_N PF08706.11 GBG77675.1 - 0.077 13.3 3.2 0.14 12.5 3.2 1.4 1 0 0 1 1 1 0 D5 N terminal like hDGE_amylase PF14701.6 GBG77675.1 - 0.079 12.0 1.8 0.11 11.6 1.8 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Spore_III_AF PF09581.10 GBG77675.1 - 3 7.8 11.6 5.2 7.1 11.6 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Eapp_C PF10238.9 GBG77675.1 - 7.9 6.6 7.1 26 4.9 2.7 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein Actin PF00022.19 GBG77676.1 - 8.8e-150 498.8 0.0 2.9e-149 497.1 0.0 1.6 1 1 0 1 1 1 1 Actin PAPS_reduct PF01507.19 GBG77677.1 - 7.8e-43 146.5 0.0 1.1e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 GBG77677.1 - 2.3e-05 24.3 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Collagen PF01391.18 GBG77677.1 - 0.11 12.3 0.3 0.11 12.3 0.3 2.5 2 1 1 3 3 3 0 Collagen triple helix repeat (20 copies) TILa PF12714.7 GBG77677.1 - 3.1 7.8 6.7 0.96 9.4 2.0 2.3 2 0 0 2 2 2 0 TILa domain CDC73_N PF16050.5 GBG77678.1 - 0.26 10.6 5.8 0.42 9.9 5.8 1.2 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal SNARE PF05739.19 GBG77679.1 - 6.2e-17 61.3 3.5 1.6e-16 60.1 3.5 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 GBG77679.1 - 7.7e-06 25.7 15.4 0.006 16.3 4.3 2.9 3 0 0 3 3 3 2 Syntaxin Syntaxin_2 PF14523.6 GBG77679.1 - 0.0034 17.7 9.1 0.0034 17.7 9.1 2.7 2 1 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.21 GBG77679.1 - 0.013 15.3 7.1 0.013 15.3 7.1 2.9 4 0 0 4 4 4 0 Synaptobrevin MCPsignal PF00015.21 GBG77679.1 - 0.039 13.8 4.2 0.092 12.6 1.1 2.6 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Use1 PF09753.9 GBG77679.1 - 0.055 13.2 13.0 0.094 12.4 13.0 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Orf78 PF06024.12 GBG77679.1 - 0.088 13.1 1.3 0.23 11.8 1.3 1.7 1 0 0 1 1 1 0 Orf78 (ac78) TMCO5 PF14992.6 GBG77679.1 - 0.46 10.0 13.5 1.2 8.7 13.5 1.7 1 1 0 1 1 1 0 TMCO5 family T2SSF PF00482.23 GBG77679.1 - 1.1 9.3 5.8 0.45 10.5 1.6 2.3 2 2 0 2 2 2 0 Type II secretion system (T2SS), protein F COG5 PF10392.9 GBG77679.1 - 1.4 9.1 8.6 0.37 11.0 0.8 2.6 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Prominin PF05478.11 GBG77679.1 - 5.4 4.9 12.4 0.36 8.7 3.9 2.0 1 1 0 2 2 2 0 Prominin DUF5383 PF17355.2 GBG77679.1 - 5.7 7.3 7.6 0.35 11.2 0.8 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5383) DUF4315 PF14193.6 GBG77679.1 - 5.7 7.0 13.7 4.7 7.3 0.6 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4315) Tyrosinase PF00264.20 GBG77680.1 - 5e-23 82.6 24.3 5.3e-16 59.6 2.1 3.8 2 2 2 4 4 4 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG77680.1 - 3.8e-15 55.4 0.2 7.9e-15 54.4 0.2 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain PPO1_KFDV PF12143.8 GBG77680.1 - 0.00014 22.0 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF_B2219) Myb_DNA-binding PF00249.31 GBG77681.1 - 1.4e-08 34.8 0.1 4.2e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG77681.1 - 0.0001 22.4 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG77681.1 - 0.014 15.5 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Nop14 PF04147.12 GBG77681.1 - 0.019 13.2 48.8 0.034 12.4 48.8 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG77681.1 - 0.45 9.9 53.8 0.92 8.9 53.8 1.4 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 GBG77681.1 - 0.82 9.2 43.0 1.9 8.0 43.0 1.6 1 0 0 1 1 1 0 PPP4R2 Pkinase_Tyr PF07714.17 GBG77683.1 - 8.7e-48 162.8 0.0 1.1e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG77683.1 - 1.7e-43 148.9 0.0 2.3e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG77683.1 - 0.0025 16.7 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG77683.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 GBG77686.1 - 3.2e-23 81.7 0.0 1.2e-22 79.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77686.1 - 1.7e-19 70.3 0.0 2.8e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77686.1 - 1.3e-14 54.3 0.0 4.7e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG77686.1 - 6.4e-07 29.2 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77686.1 - 0.00012 22.6 0.0 0.00034 21.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77686.1 - 0.0014 19.2 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SlyX PF04102.12 GBG77686.1 - 0.0051 17.4 0.9 0.16 12.6 0.2 2.9 2 0 0 2 2 2 1 SlyX SQS_PSY PF00494.19 GBG77687.1 - 3.1e-50 171.1 0.8 4.1e-50 170.7 0.8 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase BLM10_mid PF16507.5 GBG77688.1 - 4.2e-56 190.7 0.0 1.7e-28 99.6 0.0 4.0 4 0 0 4 4 4 3 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 GBG77688.1 - 1.9e-31 107.8 0.0 3.8e-30 103.6 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) HEAT PF02985.22 GBG77688.1 - 1e-05 25.4 0.3 0.031 14.5 0.1 3.3 2 0 0 2 2 2 2 HEAT repeat CLASP_N PF12348.8 GBG77688.1 - 0.21 11.1 0.8 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal RVT_1 PF00078.27 GBG77689.1 - 1.5e-24 86.8 0.0 3e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77689.1 - 2.9e-17 62.5 0.6 4.3e-16 58.8 0.2 2.8 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG77689.1 - 4.2e-11 42.8 0.0 1.3e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77689.1 - 2.4e-09 37.4 0.1 1.4e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG77689.1 - 1.1e-07 32.4 0.0 3.8e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77689.1 - 7.2e-07 29.7 0.0 1.9e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG77689.1 - 1.6e-06 28.3 0.1 0.0059 16.9 0.0 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG77689.1 - 2e-05 24.3 0.0 4.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG77689.1 - 0.00032 20.5 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG77689.1 - 0.0041 17.4 0.7 0.12 12.7 0.0 3.6 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG77689.1 - 0.026 14.7 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF4407 PF14362.6 GBG77689.1 - 4.5 6.5 12.9 1.8 7.9 4.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Cpn60_TCP1 PF00118.24 GBG77690.1 - 2.3e-165 550.9 1.3 2.7e-165 550.7 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribonuc_P_40 PF08584.11 GBG77691.1 - 7.2e-54 183.0 0.0 3.5e-52 177.4 0.0 2.3 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit rve PF00665.26 GBG77691.1 - 1.6e-05 25.1 0.0 5.1e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Na_trans_assoc PF06512.13 GBG77691.1 - 0.14 12.4 13.6 0.25 11.6 13.6 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG77691.1 - 0.94 8.8 23.4 1.7 8.0 23.4 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG77691.1 - 1.5 6.9 24.0 2.1 6.5 24.0 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG77691.1 - 2.1 7.1 6.6 3.1 6.5 6.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pyrophosphatase PF00719.19 GBG77692.1 - 2.9e-53 179.9 0.2 4e-53 179.5 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pilus_CpaD PF09476.10 GBG77692.1 - 0.052 13.3 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Exostosin PF03016.15 GBG77693.1 - 1.1e-51 175.9 0.3 2.5e-51 174.7 0.3 1.5 1 1 0 1 1 1 1 Exostosin family KptA_kDCL PF18176.1 GBG77694.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain DUF287 PF03384.14 GBG77694.1 - 0.87 10.0 4.0 0.45 10.9 0.6 2.2 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 rve PF00665.26 GBG77695.1 - 8.9e-06 25.9 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG77695.1 - 4.6e-05 23.2 0.0 9.9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG77695.1 - 0.00051 19.8 1.2 0.0013 18.5 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG77695.1 - 0.088 13.1 0.2 0.3 11.4 0.2 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Lipin_mid PF16876.5 GBG77695.1 - 0.097 12.8 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Plavaka PF18759.1 GBG77696.1 - 1.3e-22 80.5 0.3 2.2e-22 79.7 0.3 1.3 1 0 0 1 1 1 1 Plavaka transposase TFIIF_alpha PF05793.12 GBG77696.1 - 0.017 13.7 8.5 0.027 13.1 8.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LCM PF04072.14 GBG77696.1 - 0.018 15.0 0.8 0.12 12.3 0.1 2.3 2 0 0 2 2 2 0 Leucine carboxyl methyltransferase Nucleo_P87 PF07267.11 GBG77696.1 - 0.58 9.0 2.4 0.96 8.2 2.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 GBG77696.1 - 0.72 8.1 10.6 1.2 7.3 10.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DEAD PF00270.29 GBG77697.1 - 5.2e-50 169.6 0.0 8e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG77697.1 - 3.5e-32 111.1 0.0 1.2e-30 106.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG77697.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Met_synt_B12 PF02965.17 GBG77698.1 - 9.6e-118 392.6 0.0 1.7e-117 391.8 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 GBG77698.1 - 8.4e-75 252.0 0.1 1.6e-74 251.1 0.1 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 GBG77698.1 - 2e-56 191.4 2.6 7.2e-56 189.6 0.8 2.6 3 0 0 3 3 3 1 Pterin binding enzyme B12-binding_2 PF02607.17 GBG77698.1 - 3.9e-25 88.1 0.3 1.9e-24 85.9 0.3 2.4 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 GBG77698.1 - 3.6e-19 69.0 1.5 9.6e-19 67.6 0.5 2.4 2 0 0 2 2 2 1 B12 binding domain AMPK1_CBM PF16561.5 GBG77698.1 - 5.3e-11 42.6 0.0 1.4e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF2760 PF10816.8 GBG77698.1 - 0.16 11.8 0.4 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2760) HTH_Tnp_Tc5 PF03221.16 GBG77698.1 - 0.19 11.8 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain GalKase_gal_bdg PF10509.9 GBG77699.1 - 5.6e-23 80.2 0.0 1.1e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 GBG77699.1 - 2e-13 50.5 0.1 7.4e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GBG77699.1 - 5.2e-13 49.0 3.1 9e-13 48.3 2.2 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain COX15-CtaA PF02628.15 GBG77700.1 - 5.2e-109 364.2 10.6 7.6e-109 363.7 10.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Ins_allergen_rp PF06757.13 GBG77700.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification zf-CCHC PF00098.23 GBG77702.1 - 2.7e-07 30.3 6.9 2.7e-07 30.3 6.9 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG77702.1 - 0.013 15.5 0.7 0.013 15.5 0.7 2.0 2 0 0 2 2 2 0 Zinc knuckle Prominin PF05478.11 GBG77702.1 - 0.11 10.4 3.0 0.18 9.7 3.0 1.3 1 0 0 1 1 1 0 Prominin zf-CCHC_2 PF13696.6 GBG77702.1 - 0.33 10.8 7.2 0.63 9.9 7.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG77702.1 - 0.33 10.8 3.0 0.78 9.6 2.1 2.2 2 0 0 2 2 2 0 Zinc knuckle TMEM51 PF15345.6 GBG77702.1 - 0.46 10.3 3.4 0.98 9.2 3.4 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 CLIP1_ZNF PF16641.5 GBG77702.1 - 1.8 8.5 5.5 2.9 7.9 5.5 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle Hemerythrin PF01814.23 GBG77703.1 - 0.0075 16.9 0.2 0.0096 16.5 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain COX2 PF00116.20 GBG77703.1 - 0.06 13.2 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain HAUS-augmin3 PF14932.6 GBG77703.1 - 0.066 12.8 0.1 0.086 12.4 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 zf-CCHC PF00098.23 GBG77704.1 - 0.052 13.6 2.3 0.11 12.6 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG77704.1 - 0.059 13.0 0.3 0.059 13.0 0.3 1.8 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG77704.1 - 0.14 11.9 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Gryzun PF07919.12 GBG77704.1 - 0.16 10.7 0.1 0.23 10.2 0.1 1.1 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi RVP_2 PF08284.11 GBG77704.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease PfkB PF00294.24 GBG77705.1 - 9.1e-80 268.2 0.0 1e-79 268.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MlaD PF02470.20 GBG77706.1 - 3.5e-14 52.9 0.3 6.2e-14 52.1 0.3 1.4 1 0 0 1 1 1 1 MlaD protein Rop-like PF05082.13 GBG77706.1 - 0.051 13.4 0.4 0.11 12.3 0.4 1.5 1 0 0 1 1 1 0 Rop-like zf_Hakai PF18408.1 GBG77707.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 C2H2 Hakai zinc finger domain zf-RING_5 PF14634.6 GBG77707.1 - 0.19 11.7 11.8 0.36 10.8 11.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG77707.1 - 0.87 9.5 9.8 1.7 8.6 9.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GBG77707.1 - 6.2 6.8 10.5 13 5.7 10.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NifU_N PF01592.16 GBG77708.1 - 4.7e-54 182.0 0.1 4.7e-54 182.0 0.1 1.3 2 0 0 2 2 2 1 NifU-like N terminal domain RVT_1 PF00078.27 GBG77709.1 - 1.8e-31 109.4 0.0 2.8e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77709.1 - 2.5e-30 104.5 0.0 2.8e-15 56.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77709.1 - 4.2e-28 97.7 0.0 9.3e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77709.1 - 6e-16 58.3 0.1 2.1e-15 56.6 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG77709.1 - 1.8e-12 47.0 0.0 3.7e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG77709.1 - 3.8e-10 40.0 0.3 1.5e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG77709.1 - 0.00014 22.0 0.1 0.00034 20.8 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Eapp_C PF10238.9 GBG77710.1 - 1e-13 51.6 0.3 1e-13 51.6 0.3 2.9 3 1 1 4 4 4 1 E2F-associated phosphoprotein TraB PF01963.17 GBG77710.1 - 0.03 14.2 0.4 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 TraB family S6OS1 PF15676.5 GBG77710.1 - 0.055 12.0 2.3 0.44 9.0 0.1 2.2 2 0 0 2 2 2 0 Six6 opposite strand transcript 1 family GRP PF07172.11 GBG77710.1 - 5 7.9 33.7 1.3 9.7 17.8 2.9 3 0 0 3 3 3 0 Glycine rich protein family GCIP PF13324.6 GBG77710.1 - 8.1 6.0 6.8 40 3.7 5.2 2.3 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Myb_DNA-bind_4 PF13837.6 GBG77712.1 - 1.7e-10 41.1 5.3 1.3e-09 38.3 1.0 3.1 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77712.1 - 0.013 15.8 0.3 0.036 14.4 0.3 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HemY_N PF07219.13 GBG77712.1 - 0.17 12.1 0.1 0.47 10.7 0.1 1.7 1 0 0 1 1 1 0 HemY protein N-terminus Myb_DNA-bind_5 PF13873.6 GBG77712.1 - 0.18 11.9 2.8 0.27 11.4 1.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain AOX PF01786.17 GBG77713.1 - 3.1e-82 275.3 0.1 4.6e-82 274.8 0.1 1.2 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 GBG77713.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 RVT_1 PF00078.27 GBG77714.1 - 1.7e-32 112.8 0.0 2.9e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG77714.1 - 3.9e-09 36.4 0.0 6.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77714.1 - 6.8e-05 23.4 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77714.1 - 0.00075 20.0 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG77714.1 - 0.0054 16.5 0.1 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Putative peptidase (DUF1758) DUF4399 PF14347.6 GBG77714.1 - 0.032 14.6 0.1 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) AOX PF01786.17 GBG77715.1 - 1.6e-81 273.0 0.1 2.1e-81 272.6 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase Myb_DNA-bind_4 PF13837.6 GBG77717.1 - 5.8e-09 36.2 4.9 5.6e-08 33.1 0.5 3.0 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77717.1 - 0.044 14.1 3.3 1.6 9.1 0.2 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG77719.1 - 8.9e-31 106.7 0.0 1.9e-30 105.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77719.1 - 2.1e-17 63.4 0.0 3.1e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG77719.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG77719.1 - 0.19 11.3 0.2 13 5.3 0.0 2.4 2 1 0 2 2 2 0 Transposase DDE domain ENOD93 PF03386.14 GBG77720.1 - 2e-23 82.1 2.9 2.7e-23 81.6 2.9 1.1 1 0 0 1 1 1 1 Early nodulin 93 ENOD93 protein DDE_Tnp_4 PF13359.6 GBG77721.1 - 9.5e-26 90.4 0.0 1.5e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77721.1 - 8.5e-17 61.4 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77721.1 - 0.00012 21.8 0.6 0.19 11.4 0.7 2.6 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG77721.1 - 0.058 13.8 0.1 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Transposase DDE domain SDA1 PF05285.12 GBG77722.1 - 0.001 18.6 19.4 0.0013 18.3 19.4 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG77722.1 - 0.002 16.4 23.8 0.0026 16.1 23.8 1.1 1 0 0 1 1 1 1 Nop14-like family DNA_pol_phi PF04931.13 GBG77722.1 - 0.0086 14.2 34.1 0.012 13.7 34.1 1.2 1 0 0 1 1 1 1 DNA polymerase phi Myb_DNA-bind_4 PF13837.6 GBG77722.1 - 0.0094 16.3 0.4 0.017 15.5 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain BUD22 PF09073.10 GBG77722.1 - 0.019 14.4 20.7 0.025 13.9 20.7 1.2 1 0 0 1 1 1 0 BUD22 Nop25 PF09805.9 GBG77722.1 - 0.048 14.1 5.2 0.093 13.2 5.2 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) PPP4R2 PF09184.11 GBG77722.1 - 0.18 11.3 18.6 0.36 10.4 18.6 1.5 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 GBG77722.1 - 0.51 9.0 8.3 0.69 8.6 8.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 GBG77722.1 - 0.73 8.1 19.6 1 7.5 19.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GBG77722.1 - 1.4 7.3 22.5 1.9 6.9 22.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 GBG77722.1 - 1.6 8.6 28.3 2.3 8.1 28.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 GBG77722.1 - 2.3 7.5 22.3 3.5 7.0 22.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT eIF-3c_N PF05470.12 GBG77722.1 - 3.8 5.7 9.8 5.2 5.3 9.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DDE_Tnp_4 PF13359.6 GBG77723.1 - 9.5e-26 90.4 0.0 1.5e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77723.1 - 8.5e-17 61.4 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77723.1 - 0.00012 21.8 0.6 0.19 11.4 0.7 2.6 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG77723.1 - 0.058 13.8 0.1 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Transposase DDE domain Dpy-30 PF05186.13 GBG77724.1 - 1.4e-16 59.9 1.5 1.7e-16 59.6 0.4 1.8 2 0 0 2 2 2 1 Dpy-30 motif Hanta_nucleocap PF00846.18 GBG77724.1 - 0.16 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein SUIM_assoc PF16619.5 GBG77724.1 - 6.5 6.9 13.4 12 6.0 13.4 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF5542 PF17696.1 GBG77724.1 - 7.4 6.8 6.3 15 5.7 6.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5542) RT_RNaseH PF17917.1 GBG77725.1 - 7e-22 77.7 0.0 2.3e-21 76.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77725.1 - 1.1e-21 76.7 0.0 2.7e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77725.1 - 4.3e-15 55.6 0.3 1.6e-14 53.7 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77725.1 - 1.1e-08 34.8 0.0 2.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77727.1 - 1.2e-19 70.5 0.0 2.1e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77727.1 - 9e-19 67.4 0.0 1.7e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG77727.1 - 0.0052 17.3 0.3 0.013 16.0 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77727.1 - 0.0087 16.7 0.0 0.02 15.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease CDC27 PF09507.10 GBG77727.1 - 0.19 11.1 9.8 0.29 10.5 9.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CAAD PF14159.6 GBG77728.1 - 2e-08 33.9 2.7 3.2e-08 33.3 0.3 2.8 2 0 0 2 2 2 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase CENP-F_leu_zip PF10473.9 GBG77728.1 - 0.00094 19.2 8.9 0.00094 19.2 8.9 11.9 1 1 13 14 14 14 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GRP PF07172.11 GBG77729.1 - 0.0032 18.1 15.9 0.0032 18.1 15.9 1.6 2 0 0 2 2 2 1 Glycine rich protein family Adaptin_binding PF10199.9 GBG77730.1 - 3.6e-13 50.2 0.0 1.4e-11 45.1 0.0 2.5 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.22 GBG77730.1 - 5.5e-05 22.8 0.1 0.0002 21.0 0.1 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GBG77730.1 - 0.015 15.5 0.0 0.19 11.9 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 GBG77730.1 - 0.02 15.3 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.23 GBG77731.1 - 3.8e-56 190.3 0.0 3.1e-25 88.7 0.0 4.1 4 0 0 4 4 4 3 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG77731.1 - 1.3e-14 54.5 0.2 5.6e-14 52.4 0.0 2.3 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 GBG77731.1 - 2.4e-06 27.3 1.3 2.4e-06 27.3 1.3 3.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG77731.1 - 1.4e-05 25.0 0.3 6.2e-05 22.9 0.3 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GBG77731.1 - 6.7e-05 22.7 3.0 6.7e-05 22.7 3.0 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG77731.1 - 0.00023 21.1 6.2 0.00023 21.1 6.2 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 GBG77731.1 - 0.00046 20.5 2.6 0.00046 20.5 2.6 3.4 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 GBG77731.1 - 0.00046 20.0 2.9 0.00046 20.0 2.9 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG77731.1 - 0.011 15.8 1.7 0.011 15.8 1.7 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GBG77731.1 - 0.16 12.3 4.7 0.073 13.4 0.5 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GBG77731.1 - 0.28 11.1 8.3 0.2 11.5 3.3 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GBG77731.1 - 5.2 7.2 6.2 2.6 8.2 2.2 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TTL PF03133.15 GBG77732.1 - 2.9e-38 131.7 0.0 4.4e-23 81.8 0.0 2.3 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GBG77732.1 - 4.5e-05 22.8 0.0 7.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 GBG77732.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Ish1 PF10281.9 GBG77732.1 - 0.25 11.7 0.7 0.55 10.6 0.1 1.9 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein E7 PF00527.18 GBG77732.1 - 0.36 11.1 5.9 9.9 6.4 0.1 3.2 3 0 0 3 3 3 0 E7 protein, Early protein Connexin PF00029.19 GBG77732.1 - 0.45 10.2 1.6 0.95 9.2 1.6 1.4 1 0 0 1 1 1 0 Connexin Cwf_Cwc_15 PF04889.12 GBG77734.1 - 0.028 14.2 3.7 0.034 13.9 3.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2076 PF09849.9 GBG77734.1 - 0.075 13.1 3.0 0.077 13.0 3.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Bd3614-deam PF14439.6 GBG77734.1 - 0.27 11.3 2.5 0.48 10.5 2.5 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase DUF3537 PF12056.8 GBG77734.1 - 0.36 9.6 0.1 0.36 9.6 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) NOA36 PF06524.12 GBG77734.1 - 7.4 5.8 8.9 9.5 5.4 8.9 1.2 1 0 0 1 1 1 0 NOA36 protein Myb_DNA-bind_4 PF13837.6 GBG77738.1 - 2.2e-07 31.2 5.7 3.5e-07 30.5 3.7 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77738.1 - 0.0011 19.2 2.3 0.01 16.1 0.9 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG77738.1 - 0.024 14.8 0.7 0.057 13.6 0.7 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Beta-lactamase PF00144.24 GBG77739.1 - 3.9e-40 138.1 0.0 6.1e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 GBG77739.1 - 0.049 13.2 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase enzyme family Cwf_Cwc_15 PF04889.12 GBG77740.1 - 0.66 9.7 8.1 1.2 8.8 8.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 GBG77740.1 - 0.9 10.0 9.8 0.086 13.2 2.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Myb_DNA-bind_4 PF13837.6 GBG77741.1 - 1.8e-07 31.5 4.3 2.1e-07 31.2 3.3 1.6 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain SNAP PF14938.6 GBG77743.1 - 2.8e-26 92.6 14.8 3.7e-26 92.2 14.8 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 GBG77743.1 - 2.5e-06 27.7 10.8 0.0012 19.1 1.9 3.7 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG77743.1 - 0.0016 17.9 4.8 0.004 16.6 2.6 1.6 1 1 1 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 GBG77743.1 - 0.0042 16.8 9.2 2.8 7.9 0.4 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG77743.1 - 0.016 15.3 15.1 1.9 8.8 0.3 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG77743.1 - 0.041 14.1 4.3 0.94 9.7 0.1 3.4 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GBG77743.1 - 0.15 12.6 7.7 3.2 8.4 1.5 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG77743.1 - 0.41 11.0 16.5 0.68 10.3 0.1 5.5 5 2 2 7 7 7 0 Tetratricopeptide repeat PMEI PF04043.15 GBG77743.1 - 1.6 9.1 5.1 0.72 10.2 0.6 2.3 1 1 2 3 3 2 0 Plant invertase/pectin methylesterase inhibitor TPR_10 PF13374.6 GBG77743.1 - 2.3 8.2 5.2 13 5.8 0.2 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG77743.1 - 4 8.3 12.0 5.5 7.9 0.2 5.3 4 2 2 6 6 6 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.6 GBG77744.1 - 0.0012 19.2 0.3 0.0021 18.4 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG77745.1 - 2.4e-25 88.5 0.0 4.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77745.1 - 1.4e-19 70.3 0.0 2.7e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77745.1 - 4.5e-12 46.0 0.0 6.4e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG77745.1 - 0.96 8.7 21.7 1.3 8.3 21.7 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG77745.1 - 1.9 6.7 17.0 2.7 6.2 17.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG77745.1 - 6.5 6.1 22.8 9.2 5.6 22.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG77745.1 - 9.6 4.3 24.0 15 3.6 24.0 1.2 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_4 PF13837.6 GBG77746.1 - 2.7e-05 24.4 1.9 5.5e-05 23.5 1.1 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG77746.1 - 0.01 15.9 0.7 0.024 14.7 0.7 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG77746.1 - 0.16 12.2 0.1 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Retrotrans_gag PF03732.17 GBG77748.1 - 3.2e-05 24.1 8.9 0.0064 16.7 0.0 4.3 4 2 0 4 4 4 2 Retrotransposon gag protein CLZ PF16526.5 GBG77748.1 - 2.1 8.7 10.6 0.076 13.4 1.0 3.4 4 1 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Myb_DNA-bind_4 PF13837.6 GBG77749.1 - 2.3e-08 34.3 5.2 2.3e-08 34.3 5.2 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG77749.1 - 0.00026 21.0 1.0 0.00062 19.8 1.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG77749.1 - 0.0015 18.8 4.1 0.0018 18.6 2.8 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG77749.1 - 0.0019 18.4 1.0 0.0049 17.1 1.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG77749.1 - 0.07 13.3 1.0 0.21 11.8 1.0 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain RNA_pol_3_Rpc31 PF11705.8 GBG77750.1 - 0.45 10.7 26.0 0.55 10.5 26.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 GBG77750.1 - 2.2 7.8 24.0 2.3 7.8 24.0 1.0 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 GBG77750.1 - 3 7.1 11.4 3.4 6.9 11.4 1.2 1 0 0 1 1 1 0 NOA36 protein Perilipin PF03036.16 GBG77750.1 - 3.3 6.6 15.2 3.5 6.6 15.2 1.0 1 0 0 1 1 1 0 Perilipin family DUF4581 PF15167.6 GBG77751.1 - 0.091 12.9 0.2 0.45 10.7 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) PepSY_2 PF13670.6 GBG77751.1 - 1.2 9.2 5.4 19 5.3 0.0 4.1 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain Ribonuclease_3 PF00636.26 GBG77752.1 - 3e-39 133.9 0.6 2e-20 73.4 0.0 3.5 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GBG77752.1 - 6.5e-25 87.7 0.2 4e-10 40.0 0.0 4.5 4 0 0 4 4 4 3 Ribonuclease-III-like RT_RNaseH_2 PF17919.1 GBG77752.1 - 5.3e-18 64.9 0.0 1.3e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77752.1 - 5.8e-07 29.8 0.0 1.6e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG77752.1 - 0.16 12.0 2.7 0.35 10.9 2.7 1.5 1 0 0 1 1 1 0 Zinc knuckle PCEMA1 PF07418.11 GBG77753.1 - 0.4 10.1 14.5 0.66 9.4 14.5 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 RT_RNaseH_2 PF17919.1 GBG77754.1 - 1.5e-25 89.2 0.0 3.1e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77754.1 - 9.4e-24 83.7 0.0 1.8e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77754.1 - 2.4e-16 59.6 0.6 6.1e-16 58.3 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG77754.1 - 0.00013 22.5 0.0 0.00037 21.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG77754.1 - 0.0037 17.5 4.4 0.015 15.5 0.1 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG77754.1 - 0.0069 16.9 0.0 0.02 15.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77754.1 - 0.097 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG77755.1 - 5.6e-23 81.2 0.0 1.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77755.1 - 3.9e-19 68.5 0.0 7.7e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77755.1 - 4.6e-15 55.5 0.0 1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77755.1 - 9e-15 54.9 0.0 2.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG77758.1 - 0.0086 16.3 4.1 1.4 9.2 0.1 3.2 3 0 0 3 3 3 2 Retrotransposon gag protein EzrA PF06160.12 GBG77758.1 - 0.019 13.2 0.0 0.019 13.2 0.0 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF1081 PF06448.11 GBG77758.1 - 0.12 12.8 0.2 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) TFIIA PF03153.13 GBG77758.1 - 0.3 11.0 19.8 0.43 10.5 19.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RVT_1 PF00078.27 GBG77760.1 - 3.8e-29 101.8 0.0 5.7e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77760.1 - 5.3e-15 55.3 0.0 1.2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DEAD PF00270.29 GBG77760.1 - 5.9e-05 22.9 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GBG77760.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RT_RNaseH PF17917.1 GBG77760.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77761.1 - 5e-16 58.9 0.6 2.7e-09 36.9 0.1 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77762.1 - 1.8e-28 98.5 0.0 2.8e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77762.1 - 1e-26 93.2 0.0 1.6e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77762.1 - 3.6e-09 36.5 0.0 5.3e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG77762.1 - 0.055 13.4 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) DUF3807 PF12720.7 GBG77763.1 - 0.14 12.4 13.5 0.19 12.0 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2201_N PF13203.6 GBG77763.1 - 0.21 11.2 6.1 0.27 10.8 6.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain SDA1 PF05285.12 GBG77763.1 - 0.4 10.1 25.2 0.52 9.7 25.2 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG77763.1 - 1.1 7.9 3.8 1.2 7.9 3.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG77763.1 - 4.1 5.5 25.5 5.3 5.1 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG77763.1 - 5.7 6.6 20.6 8.3 6.1 20.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RVT_1 PF00078.27 GBG77764.1 - 2.3e-05 24.0 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG77764.1 - 0.0043 17.6 0.0 0.015 15.9 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77764.1 - 0.03 15.0 0.0 0.068 13.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Prominin PF05478.11 GBG77764.1 - 0.14 10.1 3.7 0.26 9.2 3.7 1.3 1 0 0 1 1 1 0 Prominin Ribosomal_L29 PF00831.23 GBG77764.1 - 1.6 8.7 11.5 8 6.5 0.3 3.1 2 0 0 2 2 2 0 Ribosomal L29 protein Snapin_Pallidin PF14712.6 GBG77764.1 - 2.4 8.6 7.7 8.1 6.9 2.9 3.2 3 0 0 3 3 3 0 Snapin/Pallidin COMP PF11598.8 GBG77764.1 - 2.8 8.5 5.4 8.5 6.9 5.4 1.8 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein DUF659 PF04937.15 GBG77765.1 - 4.6e-34 117.5 0.1 6.9e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG77765.1 - 0.00015 21.5 0.2 0.0003 20.5 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG77766.1 - 1.1e-09 38.1 0.0 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG77766.1 - 0.012 13.9 21.3 0.016 13.5 21.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG77766.1 - 0.015 13.9 22.7 0.02 13.5 22.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 GBG77766.1 - 0.03 13.8 24.7 0.039 13.4 24.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG77766.1 - 0.076 11.2 26.5 0.1 10.8 26.5 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG77766.1 - 0.094 12.8 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase PLATZ PF04640.14 GBG77766.1 - 0.14 12.8 3.8 1.1 9.9 3.8 2.2 1 1 0 1 1 1 0 PLATZ transcription factor Mpp10 PF04006.12 GBG77766.1 - 0.36 9.2 29.3 0.49 8.8 29.3 1.1 1 0 0 1 1 1 0 Mpp10 protein Na_trans_assoc PF06512.13 GBG77766.1 - 0.55 10.5 19.7 0.99 9.7 19.7 1.5 1 1 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 GBG77766.1 - 0.56 9.5 24.8 0.72 9.1 24.8 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG77766.1 - 0.74 9.3 13.8 0.95 9.0 13.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 GBG77766.1 - 2.2 7.4 7.0 3.2 6.9 7.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 GBG77766.1 - 3.9 7.2 21.3 6.1 6.6 21.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4683 PF15735.5 GBG77766.1 - 5.4 6.5 14.1 7.3 6.1 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) LAP1C PF05609.12 GBG77766.1 - 6 5.8 13.8 7.7 5.5 13.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SAPS PF04499.15 GBG77766.1 - 6.3 5.5 11.6 8.3 5.1 11.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ebola_NP PF05505.12 GBG77766.1 - 6.3 5.0 10.2 8.6 4.5 10.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Apt1 PF10351.9 GBG77766.1 - 6.5 5.5 10.4 8.4 5.1 10.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Afi1 PF07792.12 GBG77766.1 - 8.8 6.8 14.0 15 6.0 14.0 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 GBG77767.1 - 0.0069 14.7 20.6 0.0089 14.4 20.6 1.1 1 0 0 1 1 1 1 CDC45-like protein TFIIF_alpha PF05793.12 GBG77767.1 - 0.0089 14.7 22.1 0.012 14.3 22.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 GBG77767.1 - 0.027 13.9 24.8 0.035 13.6 24.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG77767.1 - 0.1 10.8 27.0 0.13 10.4 27.0 1.1 1 0 0 1 1 1 0 Nop14-like family PLATZ PF04640.14 GBG77767.1 - 0.13 12.9 3.8 1 10.0 3.8 2.1 1 1 0 1 1 1 0 PLATZ transcription factor Mpp10 PF04006.12 GBG77767.1 - 0.34 9.3 29.3 0.44 8.9 29.3 1.1 1 0 0 1 1 1 0 Mpp10 protein Na_trans_assoc PF06512.13 GBG77767.1 - 0.5 10.6 19.7 0.89 9.8 19.7 1.5 1 1 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 GBG77767.1 - 0.51 9.6 24.8 0.65 9.3 24.8 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG77767.1 - 0.66 9.5 13.9 0.84 9.1 13.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 GBG77767.1 - 1.7 7.8 6.8 2.5 7.2 6.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 GBG77767.1 - 3.7 7.3 21.3 5.5 6.7 21.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4683 PF15735.5 GBG77767.1 - 4.8 6.7 14.1 6.5 6.3 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) LAP1C PF05609.12 GBG77767.1 - 5.5 6.0 13.8 6.9 5.6 13.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SAPS PF04499.15 GBG77767.1 - 5.7 5.6 11.6 7.4 5.2 11.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ebola_NP PF05505.12 GBG77767.1 - 5.8 5.1 10.2 7.8 4.7 10.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Apt1 PF10351.9 GBG77767.1 - 6.5 5.5 10.5 8.4 5.1 10.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Afi1 PF07792.12 GBG77767.1 - 6.5 7.2 13.8 11 6.5 13.8 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 GBG77767.1 - 8.8 5.0 17.1 12 4.5 17.1 1.1 1 0 0 1 1 1 0 Presenilin Paf1 PF03985.13 GBG77767.1 - 9.3 5.1 29.8 14 4.5 29.8 1.3 1 0 0 1 1 1 0 Paf1 DDE_Tnp_4 PF13359.6 GBG77768.1 - 3.8e-31 107.9 0.0 6.7e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77768.1 - 1.4e-15 57.4 0.0 2.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77768.1 - 4.6e-05 23.2 0.0 0.047 13.3 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain DUF2785 PF10978.8 GBG77769.1 - 0.17 11.6 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) LIN52 PF10044.9 GBG77770.1 - 0.091 13.5 0.0 0.56 11.0 0.0 2.3 2 0 0 2 2 2 0 Retinal tissue protein aGPT-Pplase2 PF18724.1 GBG77770.1 - 0.23 11.2 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 Cupin_1 PF00190.22 GBG77771.1 - 7.4e-32 110.0 0.1 1e-31 109.6 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 GBG77771.1 - 3.7e-12 45.8 0.0 5.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 GBG77771.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 GBG77771.1 - 0.085 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 GBG77771.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Ldh_1_N PF00056.23 GBG77773.1 - 1.7e-44 151.3 0.2 3.1e-44 150.5 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 GBG77773.1 - 1.9e-23 83.2 0.0 3.3e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 GBG77773.1 - 0.029 13.9 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase TPR_19 PF14559.6 GBG77774.1 - 1.2e-11 44.9 13.0 0.00039 20.9 1.3 6.1 6 1 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG77774.1 - 6e-11 42.4 26.7 0.00096 19.3 1.9 5.6 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 GBG77774.1 - 1.3e-06 28.4 0.4 0.062 13.4 1.5 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG77774.1 - 4e-06 27.4 2.5 0.75 10.5 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG77774.1 - 8.3e-06 26.2 7.4 9.2 7.4 0.2 7.1 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 GBG77774.1 - 0.00051 20.5 5.9 0.98 10.2 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 GBG77774.1 - 0.003 17.6 9.0 0.62 10.1 3.5 3.3 3 1 0 3 3 3 2 Putative TPR-like repeat TPR_12 PF13424.6 GBG77774.1 - 0.0094 16.2 17.0 8.6 6.7 1.5 7.1 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 GBG77774.1 - 0.11 13.1 0.0 18 6.4 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG77774.1 - 0.3 11.2 14.5 0.39 10.9 0.5 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG77774.1 - 0.31 11.2 38.6 1 9.6 1.0 9.0 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG77774.1 - 2.8 8.4 13.5 32 5.1 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG77775.1 - 1.2e-31 110.0 0.0 1.8e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pneumo_phosprot PF02478.16 GBG77775.1 - 0.17 11.4 1.1 2.5 7.5 1.2 2.0 1 1 1 2 2 2 0 Pneumovirus phosphoprotein DUF4366 PF14283.6 GBG77776.1 - 0.00015 21.8 9.7 0.016 15.3 2.7 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4366) FAM176 PF14851.6 GBG77776.1 - 0.0038 16.9 0.9 0.0038 16.9 0.9 2.4 2 1 0 2 2 2 1 FAM176 family Connexin PF00029.19 GBG77776.1 - 0.0079 16.0 0.2 0.17 11.6 0.3 2.1 2 0 0 2 2 2 1 Connexin DUF4064 PF13273.6 GBG77776.1 - 0.018 15.3 0.0 0.82 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) TRAP_alpha PF03896.16 GBG77776.1 - 0.041 13.1 4.7 0.16 11.1 3.3 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 GBG77776.1 - 0.042 13.2 11.2 0.057 12.8 11.2 1.1 1 0 0 1 1 1 0 BUD22 PBP1_TM PF14812.6 GBG77776.1 - 0.045 14.1 2.6 4.2 7.8 2.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 GBG77776.1 - 0.047 14.1 14.3 11 6.5 0.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FHIPEP PF00771.20 GBG77776.1 - 0.05 12.1 0.1 0.079 11.4 0.1 1.3 1 0 0 1 1 1 0 FHIPEP family DUF4604 PF15377.6 GBG77776.1 - 0.055 13.9 8.4 0.071 13.5 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CDC27 PF09507.10 GBG77776.1 - 0.063 12.7 8.7 0.08 12.3 8.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PIP5K PF01504.18 GBG77776.1 - 0.065 12.4 0.0 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Presenilin PF01080.17 GBG77776.1 - 0.066 12.0 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Presenilin MFS_1_like PF12832.7 GBG77776.1 - 0.07 12.0 0.0 0.36 9.6 0.0 1.9 1 1 0 1 1 1 0 MFS_1 like family DUF913 PF06025.12 GBG77776.1 - 0.071 12.1 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RRN3 PF05327.11 GBG77776.1 - 0.071 11.6 1.6 0.095 11.2 1.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Afi1 PF07792.12 GBG77776.1 - 0.081 13.4 3.0 0.38 11.2 1.6 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Orf78 PF06024.12 GBG77776.1 - 0.098 13.0 0.5 2.1 8.7 0.2 2.3 2 1 0 2 2 2 0 Orf78 (ac78) DUF4199 PF13858.6 GBG77776.1 - 0.1 13.0 2.6 7.6 6.9 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Peroxin-13_N PF04088.13 GBG77776.1 - 0.21 11.9 0.0 1.4 9.2 0.0 1.9 2 0 0 2 2 2 0 Peroxin 13, N-terminal region THOC2_N PF16134.5 GBG77776.1 - 0.33 9.5 5.8 0.067 11.8 2.6 1.3 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus ORC_WH_C PF18137.1 GBG77776.1 - 0.42 10.7 7.8 4.9 7.2 7.3 2.0 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal CbtA PF09490.10 GBG77776.1 - 0.43 10.3 2.1 2.4 7.9 1.0 2.0 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) TFB6 PF17110.5 GBG77776.1 - 0.49 10.1 6.3 0.085 12.6 1.5 1.9 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Conotoxin PF02950.17 GBG77776.1 - 0.49 11.4 0.0 0.49 11.4 0.0 2.4 2 1 1 3 3 2 0 Conotoxin RXT2_N PF08595.11 GBG77776.1 - 0.61 10.1 7.9 0.087 12.9 1.7 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal V_ATPase_I PF01496.19 GBG77776.1 - 0.61 7.9 6.0 1.1 7.1 6.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPR3 PF03666.13 GBG77776.1 - 0.76 8.5 4.0 0.2 10.4 1.3 1.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 GBG77776.1 - 1.3 8.4 19.0 0.099 12.0 10.8 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RAB3GAP2_C PF14656.6 GBG77776.1 - 1.3 7.2 3.3 1.1 7.4 2.0 1.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Sigma70_ner PF04546.13 GBG77776.1 - 1.8 8.4 18.8 0.032 14.1 8.3 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region eIF-3c_N PF05470.12 GBG77776.1 - 2.3 6.4 6.5 3 6.0 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AIF_C PF14721.6 GBG77776.1 - 4.2 7.7 5.0 6.5 7.1 3.0 1.9 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Zip PF02535.22 GBG77776.1 - 8.1 5.5 5.8 16 4.6 5.4 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter Mak16 PF04874.14 GBG77776.1 - 9.6 6.9 26.8 9.8 6.9 18.1 2.1 2 0 0 2 2 2 0 Mak16 protein C-terminal region REV PF00424.18 GBG77777.1 - 1 9.4 5.2 2.7 8.1 0.1 3.2 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) TPR_11 PF13414.6 GBG77778.1 - 3.9e-12 45.6 12.6 0.0024 17.5 0.1 4.9 5 0 0 5 5 5 4 TPR repeat TOM20_plant PF06552.12 GBG77778.1 - 1e-08 35.2 1.9 0.00055 19.7 1.9 2.9 2 1 1 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 SDA1 PF05285.12 GBG77778.1 - 0.013 15.0 24.1 0.021 14.2 24.1 1.4 1 0 0 1 1 1 0 SDA1 TPR_17 PF13431.6 GBG77778.1 - 0.015 15.6 5.6 0.12 12.8 0.5 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC45 PF02724.14 GBG77778.1 - 0.03 12.6 18.7 0.036 12.4 17.8 1.5 2 0 0 2 2 2 0 CDC45-like protein FAT PF02259.23 GBG77778.1 - 0.69 9.1 8.0 0.63 9.2 0.6 2.8 2 1 1 3 3 3 0 FAT domain TFIIA PF03153.13 GBG77778.1 - 3.2 7.7 17.9 0.68 9.9 13.7 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 GBG77778.1 - 8.5 5.0 7.8 12 4.5 7.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ASH PF15780.5 GBG77779.1 - 2.4e-15 56.5 0.3 0.23 11.7 0.0 8.7 9 0 0 9 9 9 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CH PF00307.31 GBG77779.1 - 8.2e-06 26.0 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Motile_Sperm PF00635.26 GBG77779.1 - 2e-05 24.4 0.0 0.016 15.0 0.1 4.2 4 0 0 4 4 4 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 GBG77779.1 - 9.5e-05 22.6 0.3 3 8.1 0.0 4.9 4 0 0 4 4 4 2 Transmembrane protein 131-like Acetyltransf_1 PF00583.25 GBG77780.1 - 8.8e-18 64.6 0.0 1.5e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GBG77780.1 - 1.2e-09 38.2 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GBG77780.1 - 4.9e-08 33.3 0.0 9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG77780.1 - 0.0021 18.0 0.0 0.0057 16.6 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Polyoma_lg_T_C PF06431.11 GBG77780.1 - 0.032 13.1 4.3 0.05 12.5 4.3 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Acetyltransf_3 PF13302.7 GBG77780.1 - 0.07 13.8 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SDA1 PF05285.12 GBG77780.1 - 0.074 12.5 14.6 0.11 11.9 14.6 1.3 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 GBG77780.1 - 0.081 12.3 11.1 0.13 11.7 11.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GBG77780.1 - 1.3 7.2 14.7 1.8 6.8 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 GBG77780.1 - 1.3 8.5 13.8 2 7.9 13.8 1.3 1 0 0 1 1 1 0 PPP4R2 CNDH2_C PF16858.5 GBG77780.1 - 1.5 8.7 7.1 2.2 8.1 7.1 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term TFB6 PF17110.5 GBG77780.1 - 1.5 8.5 11.7 2.9 7.6 11.7 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop14 PF04147.12 GBG77780.1 - 6.6 4.8 21.5 9.3 4.3 21.5 1.1 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.11 GBG77780.1 - 7.7 4.8 11.9 9.7 4.5 11.9 1.1 1 0 0 1 1 1 0 SGT1 protein CAP_N PF01213.19 GBG77781.1 - 0.42 10.0 11.0 0.79 9.1 11.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GBG77781.1 - 8.2 6.4 12.6 0.34 11.0 7.0 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator GlutR_dimer PF00745.20 GBG77782.1 - 0.2 12.1 13.7 0.45 11.0 2.5 3.4 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain ASH PF15780.5 GBG77783.1 - 2e-08 34.3 1.1 0.029 14.6 0.1 3.3 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF5308 PF17233.2 GBG77783.1 - 6.2e-05 23.3 7.0 9e-05 22.8 7.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Myc_N PF01056.18 GBG77783.1 - 0.0012 18.9 12.5 0.0015 18.5 12.5 1.2 1 0 0 1 1 1 1 Myc amino-terminal region BUD22 PF09073.10 GBG77783.1 - 0.0025 17.3 30.7 0.003 17.0 30.7 1.1 1 0 0 1 1 1 1 BUD22 Rtf2 PF04641.12 GBG77783.1 - 0.004 16.6 25.4 0.0053 16.2 25.4 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger GAGA_bind PF06217.12 GBG77783.1 - 0.008 16.5 15.5 0.013 15.8 15.5 1.4 1 0 0 1 1 1 1 GAGA binding protein-like family RNA_pol_Rpc4 PF05132.14 GBG77783.1 - 0.0089 16.5 15.8 0.016 15.6 15.8 1.5 1 0 0 1 1 1 1 RNA polymerase III RPC4 fn3_6 PF17766.1 GBG77783.1 - 0.017 15.3 0.1 2.3 8.5 0.4 3.1 2 2 0 2 2 2 0 Fibronectin type-III domain SAPS PF04499.15 GBG77783.1 - 0.02 13.7 11.8 0.023 13.5 11.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein U79_P34 PF03064.16 GBG77783.1 - 0.06 12.7 21.3 0.11 11.8 21.3 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FapA PF03961.13 GBG77783.1 - 0.063 11.9 16.6 0.086 11.4 16.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CSRNP_N PF16019.5 GBG77783.1 - 0.07 13.0 15.5 0.14 12.1 15.5 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FAM60A PF15396.6 GBG77783.1 - 0.074 13.1 25.0 0.1 12.6 25.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF1168 PF06658.12 GBG77783.1 - 0.084 12.7 44.9 0.13 12.1 44.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) AAA_11 PF13086.6 GBG77783.1 - 0.15 11.9 20.0 0.21 11.3 20.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_pol_3_Rpc31 PF11705.8 GBG77783.1 - 0.47 10.7 34.9 0.68 10.1 34.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 EOS1 PF12326.8 GBG77783.1 - 0.88 9.5 7.8 1.5 8.7 7.8 1.5 1 0 0 1 1 1 0 N-glycosylation protein DUF3807 PF12720.7 GBG77783.1 - 1.2 9.4 31.7 1.8 8.8 31.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SID-1_RNA_chan PF13965.6 GBG77783.1 - 1.2 7.4 7.1 1.6 7.1 7.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF3_subunit PF08597.10 GBG77783.1 - 1.8 8.4 43.5 3.1 7.6 43.5 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4746 PF15928.5 GBG77783.1 - 2 7.7 32.3 3 7.2 32.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CRT10 PF08728.10 GBG77783.1 - 2.1 6.4 10.9 3 5.9 10.9 1.3 1 0 0 1 1 1 0 CRT10 Neur_chan_memb PF02932.16 GBG77783.1 - 2.3 8.2 13.6 3.3 7.7 13.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Endostatin PF06482.11 GBG77783.1 - 3.2 7.1 14.0 4.7 6.6 14.0 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin NARP1 PF12569.8 GBG77783.1 - 4.5 6.1 36.6 7 5.4 36.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GREB1 PF15782.5 GBG77783.1 - 4.9 4.1 17.9 5.7 3.9 17.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Afi1 PF07792.12 GBG77783.1 - 9.4 6.7 23.8 17 5.9 23.8 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ASH PF15780.5 GBG77784.1 - 3.5e-08 33.6 1.3 0.004 17.3 0.0 4.8 4 1 1 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 GBG77784.1 - 3.5e-07 30.4 0.0 0.00014 22.0 0.0 2.8 3 0 0 3 3 3 2 Transmembrane protein 131-like DUF1573 PF07610.11 GBG77784.1 - 0.00019 21.4 0.0 6.3 6.9 0.0 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF1573) RSF PF14876.6 GBG77784.1 - 0.068 12.1 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator DUF913 PF06025.12 GBG77785.1 - 5 6.0 6.3 5.8 5.8 6.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Integrase_H2C2 PF17921.1 GBG77788.1 - 6.1e-18 64.7 0.2 1.1e-17 63.8 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG77788.1 - 1e-08 35.4 0.0 2.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77788.1 - 3.8e-08 33.5 0.0 2.2e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG77788.1 - 1.2e-07 31.5 0.0 2.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77788.1 - 6.3e-06 26.8 0.0 1.4e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77788.1 - 0.0013 19.2 0.0 0.0029 18.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG77788.1 - 0.0045 17.2 0.0 0.033 14.4 0.0 2.5 3 0 0 3 3 3 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG77788.1 - 0.031 14.3 0.0 0.085 12.9 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG77788.1 - 0.065 13.5 0.3 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Integrin_b_cyt PF08725.11 GBG77788.1 - 0.15 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain eIF3_subunit PF08597.10 GBG77788.1 - 3.1 7.6 10.8 5 7.0 10.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Peptidase_S9 PF00326.21 GBG77789.1 - 1.2e-21 77.2 0.0 2.7e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family rve PF00665.26 GBG77789.1 - 9.7e-14 51.6 0.0 2.9e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG77789.1 - 1.1e-06 28.3 0.0 0.0017 17.9 0.0 3.1 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Abhydrolase_6 PF12697.7 GBG77789.1 - 0.00016 22.3 0.5 0.00099 19.8 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 GBG77789.1 - 0.011 15.3 0.0 0.049 13.2 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GBG77789.1 - 0.011 15.0 0.1 0.21 10.8 0.0 2.3 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GBG77789.1 - 0.014 15.2 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.20 GBG77789.1 - 0.085 12.5 0.0 0.37 10.4 0.0 2.1 1 0 0 1 1 1 0 Putative esterase LIDHydrolase PF10230.9 GBG77789.1 - 0.091 12.3 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase zf-CCHC PF00098.23 GBG77789.1 - 0.14 12.3 0.5 0.53 10.5 0.5 2.0 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_1 PF00561.20 GBG77789.1 - 0.19 11.3 0.2 1.5 8.4 0.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold RT_RNaseH PF17917.1 GBG77790.1 - 1.3e-23 83.2 0.0 2.9e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77790.1 - 1.5e-22 80.2 0.4 2e-21 76.6 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77790.1 - 1.7e-21 76.1 0.0 3.6e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77790.1 - 3.2e-16 59.2 0.1 6.6e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77790.1 - 0.031 14.5 0.1 0.19 11.9 0.1 2.4 2 0 0 2 2 2 0 Integrase core domain Herpes_pp85 PF04637.12 GBG77790.1 - 0.38 9.1 1.5 0.66 8.3 1.5 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) GAS PF13851.6 GBG77790.1 - 2.1 7.6 5.9 1.7 8.0 1.7 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Asp_protease_2 PF13650.6 GBG77791.1 - 1.2e-07 32.2 0.0 2.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77791.1 - 1.8e-07 31.6 0.0 3.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77791.1 - 5.9e-06 26.1 0.0 1.7e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG77791.1 - 1.3e-05 25.0 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease FAT PF02259.23 GBG77791.1 - 0.18 11.0 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 FAT domain zf-CCHC_3 PF13917.6 GBG77792.1 - 0.00016 21.6 5.5 0.037 14.0 0.2 2.4 2 0 0 2 2 2 2 Zinc knuckle CpXC PF14353.6 GBG77792.1 - 0.0042 17.1 0.2 1 9.4 0.1 2.4 2 0 0 2 2 2 2 CpXC protein Retrotrans_gag PF03732.17 GBG77792.1 - 0.035 14.4 0.1 0.69 10.2 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein MDH PF02315.16 GBG77792.1 - 0.14 12.3 0.6 26 5.0 0.1 2.7 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit C1_1 PF00130.22 GBG77792.1 - 0.6 10.0 4.2 3.1 7.7 0.5 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1079 PF06435.11 GBG77792.1 - 0.63 10.3 6.9 7.3 6.9 0.3 3.1 3 0 0 3 3 3 0 Repeat of unknown function (DUF1079) Fer4_2 PF12797.7 GBG77792.1 - 1.6 9.0 4.3 11 6.4 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain RVT_1 PF00078.27 GBG77793.1 - 1.3e-25 90.2 0.0 2.1e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG77793.1 - 4.7e-09 36.7 0.0 1.1e-08 35.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77793.1 - 1.5e-07 32.0 0.0 3.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG77793.1 - 0.0091 15.8 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG77793.1 - 0.017 15.4 0.0 0.056 13.7 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein zf-FCS PF06467.14 GBG77793.1 - 0.095 12.7 1.7 0.42 10.6 0.3 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RVP PF00077.20 GBG77793.1 - 0.16 12.3 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG77793.1 - 1.8 8.8 3.4 4.6 7.5 3.4 1.7 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG77794.1 - 2.5e-30 104.4 0.0 8.8e-30 102.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77794.1 - 7.8e-29 100.0 0.1 1.8e-28 98.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77794.1 - 1.2e-12 47.9 0.0 2.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_lysozyme PF00959.19 GBG77794.1 - 0.28 11.7 1.6 1.3 9.6 0.0 2.9 4 0 0 4 4 4 0 Phage lysozyme Phage_GPO PF05929.11 GBG77794.1 - 0.88 9.1 4.1 0.86 9.2 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4404 PF14357.6 GBG77795.1 - 0.076 13.7 0.7 0.076 13.7 0.7 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) DUF4192 PF13830.6 GBG77795.1 - 0.12 12.4 17.2 0.1 12.6 8.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) BRCA-2_OB3 PF09104.10 GBG77795.1 - 0.43 10.2 3.9 0.74 9.5 0.3 2.7 3 0 0 3 3 3 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 CBP4 PF07960.11 GBG77795.1 - 3.3 7.6 7.8 1 9.2 4.3 1.9 1 1 1 2 2 2 0 CBP4 DUF3235 PF11574.8 GBG77795.1 - 3.9 8.4 9.3 53 4.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Vir_act_alpha_C PF10400.9 GBG77795.1 - 4.6 8.0 17.8 2.4 8.9 0.8 3.5 1 1 2 3 3 3 0 Virulence activator alpha C-term Asp_protease_2 PF13650.6 GBG77796.1 - 2.4e-07 31.3 0.0 4.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77796.1 - 3e-07 30.9 0.0 5.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77796.1 - 2.4e-06 27.3 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG77796.1 - 5.2e-06 26.3 0.0 9.8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG77797.1 - 3.3e-27 94.4 0.0 6.4e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77797.1 - 1.3e-24 86.5 0.0 2.6e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77797.1 - 7.9e-18 64.3 0.5 2.1e-17 62.9 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77797.1 - 5.6e-16 58.7 0.0 9.1e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG77797.1 - 1.3e-08 35.1 0.0 3.7e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG77797.1 - 0.011 15.9 0.0 0.035 14.3 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG77798.1 - 2e-36 125.6 0.1 3.6e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77798.1 - 1.2e-30 105.5 0.0 2.9e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77798.1 - 7.7e-30 103.3 0.1 1.5e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG77798.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SbcD_C PF12320.8 GBG77798.1 - 0.14 12.5 0.0 15 6.0 0.0 2.9 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain L51_S25_CI-B8 PF05047.16 GBG77798.1 - 0.16 11.9 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RT_RNaseH_2 PF17919.1 GBG77799.1 - 9.9e-29 99.3 0.0 2.4e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77799.1 - 3.2e-18 66.0 0.0 7.3e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77799.1 - 3e-15 56.4 0.3 8.1e-09 35.3 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4932 PF16286.5 GBG77799.1 - 0.12 11.7 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) Thg1C PF14413.6 GBG77799.1 - 2.2 8.5 6.0 27 4.9 0.5 3.0 3 0 0 3 3 3 0 Thg1 C terminal domain PcfK PF14058.6 GBG77799.1 - 2.7 8.3 12.3 0.048 13.9 2.4 2.4 2 0 0 2 2 2 0 PcfK-like protein RVT_1 PF00078.27 GBG77800.1 - 5.8e-29 101.2 0.1 1e-28 100.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77800.1 - 2.2e-26 91.8 0.0 4.1e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77800.1 - 1.6e-21 76.5 0.0 2.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77800.1 - 2.7e-18 66.3 0.0 5.7e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG77800.1 - 5.3e-15 55.3 0.1 1.2e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG77800.1 - 0.0029 17.8 0.0 0.01 16.0 0.0 2.0 2 0 0 2 2 2 1 H2C2 zinc finger Rdx PF10262.9 GBG77800.1 - 0.059 13.6 0.0 1.9 8.7 0.0 2.8 3 0 0 3 3 3 0 Rdx family Chromo PF00385.24 GBG77801.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain HAUS5 PF14817.6 GBG77801.1 - 0.067 12.0 3.7 0.1 11.3 3.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 RVT_1 PF00078.27 GBG77802.1 - 1e-33 116.8 0.1 1.7e-33 116.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77802.1 - 3.4e-30 104.0 0.0 2.1e-29 101.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77802.1 - 4.8e-23 81.4 0.0 1.4e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77802.1 - 1.4e-12 47.5 0.6 3.7e-12 46.2 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain ERM PF00769.19 GBG77802.1 - 0.056 13.3 9.5 0.11 12.3 9.5 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family zf-H2C2 PF09337.10 GBG77802.1 - 0.073 13.3 0.1 0.23 11.7 0.1 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG77802.1 - 0.075 12.6 6.3 0.46 10.0 0.0 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.11 GBG77802.1 - 1.9 7.3 6.6 4.6 6.0 6.6 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein RT_RNaseH_2 PF17919.1 GBG77803.1 - 2.8e-25 88.3 0.0 4.9e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77803.1 - 1.3e-23 83.2 0.0 2.1e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77803.1 - 7.1e-15 55.1 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrin_b_cyt PF08725.11 GBG77803.1 - 0.15 11.8 0.5 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain RT_RNaseH_2 PF17919.1 GBG77804.1 - 1.6e-33 114.7 0.0 5.9e-20 71.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77804.1 - 6.6e-15 55.3 0.0 7.2e-10 39.1 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG77804.1 - 1.4e-08 34.9 4.0 0.0036 17.5 0.1 3.7 3 0 0 3 3 3 2 Retrotransposon gag protein WD40 PF00400.32 GBG77804.1 - 4.9e-06 27.2 1.1 0.098 13.6 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Chromo PF00385.24 GBG77804.1 - 0.00026 20.8 0.0 0.00064 19.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ANAPC4_WD40 PF12894.7 GBG77804.1 - 0.0058 16.9 0.1 0.02 15.2 0.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 GBG77804.1 - 0.007 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG77804.1 - 0.01 15.0 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Autophagy protein Apg17 Glyco_hydro_2_N PF02837.18 GBG77804.1 - 0.015 15.2 1.1 0.65 9.9 0.1 2.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Baculo_PEP_C PF04513.12 GBG77804.1 - 0.96 9.5 3.8 31 4.6 0.0 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus RT_RNaseH_2 PF17919.1 GBG77805.1 - 4.5e-32 110.1 0.0 9.7e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77805.1 - 1.9e-28 98.8 0.3 3.9e-28 97.8 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77805.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG77805.1 - 0.032 14.2 5.2 0.068 13.1 5.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG77805.1 - 0.074 13.3 1.9 0.25 11.7 0.0 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG77805.1 - 1.6 8.9 4.9 2.9 8.1 4.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG77807.1 - 2.3e-36 125.4 0.0 3.8e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG77807.1 - 8.3e-05 22.2 0.1 0.00018 21.1 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RT_RNaseH PF17917.1 GBG77808.1 - 4.9e-30 103.9 0.1 6.6e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77808.1 - 1.2e-24 86.2 0.0 1.7e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DEAD PF00270.29 GBG77809.1 - 6.6e-22 78.1 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GBG77809.1 - 1e-05 25.6 0.0 3.5e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RVT_1 PF00078.27 GBG77810.1 - 8.4e-30 103.9 0.1 1.5e-29 103.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C PF00271.31 GBG77810.1 - 7.5e-21 74.6 0.0 2e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RT_RNaseH_2 PF17919.1 GBG77810.1 - 2.2e-17 62.9 0.2 8.3e-17 61.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4217 PF13959.6 GBG77810.1 - 1.9e-16 60.0 0.4 4.9e-16 58.7 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RT_RNaseH PF17917.1 GBG77810.1 - 4.6e-09 36.5 0.0 2.2e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG77810.1 - 2.9e-08 34.3 0.0 1e-07 32.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77810.1 - 1.6e-07 31.8 0.0 4.9e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77810.1 - 2.7e-05 24.0 0.0 6.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG77810.1 - 0.00047 19.9 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF4187 PF13821.6 GBG77810.1 - 0.013 15.3 0.7 0.041 13.7 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) TMEM247 PF15444.6 GBG77810.1 - 0.06 13.4 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 247 CDH1_2_SANT_HL1 PF18375.1 GBG77810.1 - 0.17 12.5 0.5 9.5 7.0 0.0 3.0 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 DUF659 PF04937.15 GBG77811.1 - 1.8e-17 63.6 0.0 3.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG77812.1 - 3.1e-98 322.4 0.2 1.2e-31 108.7 0.0 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77812.1 - 3.6e-87 287.5 5.8 4e-28 97.8 0.1 3.6 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77812.1 - 4e-16 58.8 0.1 9.1e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77812.1 - 2.2e-13 50.2 0.3 5e-13 49.1 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAAA-beta PF15508.6 GBG77812.1 - 2.5e-05 24.5 0.2 4.3 7.7 0.0 4.0 3 0 0 3 3 3 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Mcp5_PH PF12814.7 GBG77812.1 - 0.0016 18.6 8.7 3.8 7.7 0.2 3.6 3 0 0 3 3 3 3 Meiotic cell cortex C-terminal pleckstrin homology DUF1564 PF07600.11 GBG77812.1 - 0.015 15.0 0.0 0.063 13.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) rve PF00665.26 GBG77812.1 - 0.02 15.1 0.7 1.2 9.3 0.1 3.7 3 0 0 3 3 3 0 Integrase core domain Rab3-GTPase_cat PF13890.6 GBG77812.1 - 0.033 13.8 14.1 1.1 8.8 0.0 4.7 5 0 0 5 5 3 0 Rab3 GTPase-activating protein catalytic subunit DUF5066 PF16728.5 GBG77812.1 - 0.045 13.1 0.2 0.7 9.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5066) zf-H2C2 PF09337.10 GBG77812.1 - 0.06 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger TOBE_2 PF08402.10 GBG77812.1 - 0.089 13.0 0.2 8 6.7 0.0 3.6 3 0 0 3 3 3 0 TOBE domain DUF2862 PF11061.8 GBG77812.1 - 0.17 11.8 1.0 21 5.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2862) PUF PF00806.19 GBG77812.1 - 0.2 11.4 0.1 16 5.4 0.0 2.7 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat zf-C4H2 PF10146.9 GBG77812.1 - 0.23 11.7 10.4 14 5.9 0.0 4.7 3 0 0 3 3 3 0 Zinc finger-containing protein DEDD_Tnp_IS110 PF01548.17 GBG77812.1 - 0.46 10.3 7.9 1.2 9.0 0.3 3.7 3 0 0 3 3 3 0 Transposase Rrn6 PF10214.9 GBG77812.1 - 0.57 8.6 32.3 0.0084 14.7 3.8 3.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription-initiation factor GAS PF13851.6 GBG77812.1 - 2.4 7.5 20.4 0.31 10.4 1.9 4.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Integrase_H2C2 PF17921.1 GBG77813.1 - 8.3e-19 67.4 0.3 2.6e-18 65.9 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77813.1 - 1.5e-14 54.1 0.0 3.7e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG77813.1 - 7.4e-08 32.6 0.0 3.9e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG77813.1 - 5.9e-07 29.7 0.0 1.8e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG77813.1 - 2.7e-06 27.9 0.0 1.1e-05 25.9 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77813.1 - 5.1e-06 27.0 0.0 3.1e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG77813.1 - 3.3e-05 24.1 0.5 0.0025 18.0 0.1 3.3 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG77813.1 - 6.8e-05 22.7 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG77813.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG77813.1 - 0.0033 17.5 0.0 0.0094 16.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG77813.1 - 0.036 14.3 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG77814.1 - 3.1e-28 98.8 0.2 6.5e-28 97.8 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77814.1 - 7e-24 83.8 0.0 2.9e-23 81.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77814.1 - 2.9e-20 72.5 0.0 1.1e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG77814.1 - 0.00015 22.0 3.6 0.0066 16.7 0.0 3.6 3 0 0 3 3 3 1 Retrotransposon gag protein TRPM_tetra PF16519.5 GBG77814.1 - 0.17 12.0 1.4 7.3 6.8 0.0 2.9 3 0 0 3 3 3 0 Tetramerisation domain of TRPM HXXSHH PF07586.11 GBG77814.1 - 9.1 5.8 10.3 4.6 6.7 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1552) NusG PF02357.19 GBG77815.1 - 2.3e-10 40.8 0.2 6.3e-10 39.4 0.0 1.9 1 1 1 2 2 2 1 Transcription termination factor nusG KOW PF00467.29 GBG77815.1 - 9.2e-05 22.3 0.9 0.00023 21.0 0.9 1.7 1 0 0 1 1 1 1 KOW motif Asp_protease_2 PF13650.6 GBG77815.1 - 0.0012 19.4 0.0 0.0038 17.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77815.1 - 0.0013 19.2 0.2 0.0048 17.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG77815.1 - 0.022 15.0 0.6 0.049 13.9 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein DNA_pol_phi PF04931.13 GBG77815.1 - 0.095 10.8 12.7 0.15 10.2 12.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi DivIC PF04977.15 GBG77815.1 - 0.13 12.1 1.1 0.55 10.0 1.1 2.1 1 0 0 1 1 1 0 Septum formation initiator PSK_trans_fac PF07704.11 GBG77815.1 - 3.9 8.3 6.3 10 7.0 0.2 3.7 2 0 0 2 2 2 0 Rv0623-like transcription factor RT_RNaseH_2 PF17919.1 GBG77816.1 - 6.5e-30 103.1 0.2 1.5e-29 101.9 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77816.1 - 2.4e-28 98.5 0.2 5.3e-28 97.4 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77816.1 - 4.4e-27 95.0 0.1 9.7e-27 93.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77816.1 - 6.6e-19 67.8 0.3 1.5e-18 66.7 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77816.1 - 4.4e-14 52.7 0.0 1.7e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG77816.1 - 0.066 13.4 1.8 0.12 12.6 0.0 2.5 2 0 0 2 2 2 0 H2C2 zinc finger DUF5095 PF17016.5 GBG77816.1 - 0.5 10.0 3.2 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) Integrase_H2C2 PF17921.1 GBG77817.1 - 4.3e-17 62.0 0.2 9.6e-17 60.8 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG77817.1 - 1.2e-15 57.7 0.5 3e-15 56.4 0.5 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77817.1 - 9.7e-10 38.7 0.0 5.2e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG77817.1 - 6.8e-08 32.5 0.8 1.5e-07 31.3 0.2 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG77817.1 - 0.095 13.0 0.6 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein Snapin_Pallidin PF14712.6 GBG77817.1 - 0.77 10.2 7.3 0.5 10.8 0.1 2.8 2 0 0 2 2 2 0 Snapin/Pallidin RVT_1 PF00078.27 GBG77818.1 - 0.017 14.6 0.3 0.025 14.1 0.3 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Bcr-Abl_Oligo PF09036.10 GBG77818.1 - 0.094 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain CstA PF02554.14 GBG77819.1 - 7.1 5.4 9.1 1e+02 1.6 0.1 5.4 5 2 4 9 9 9 0 Carbon starvation protein CstA Cep57_MT_bd PF06657.13 GBG77820.1 - 0.0092 16.4 4.6 0.03 14.8 3.0 2.4 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 DUF4939 PF16297.5 GBG77820.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Exonuc_VII_L PF02601.15 GBG77820.1 - 0.79 9.2 8.4 0.2 11.2 4.9 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4806 PF16064.5 GBG77820.1 - 0.9 9.9 4.4 24 5.3 0.2 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4806) Fmp27_WPPW PF10359.9 GBG77820.1 - 0.95 8.2 6.2 13 4.5 6.3 2.1 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1180 PF06679.12 GBG77820.1 - 2.9 8.3 6.1 12 6.3 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) F-box-like PF12937.7 GBG77821.1 - 6.8e-08 32.3 0.5 1.6e-07 31.1 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG77821.1 - 7.5e-07 28.9 0.3 2.1e-06 27.5 0.3 1.7 1 0 0 1 1 1 1 F-box domain ENTH PF01417.20 GBG77822.1 - 2.4e-05 24.4 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 GBG77822.1 - 0.03 14.2 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 VHS domain ANTH PF07651.16 GBG77822.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 ANTH domain rve PF00665.26 GBG77823.1 - 9.8e-10 38.7 0.1 2.7e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG77823.1 - 0.015 15.1 0.0 0.046 13.5 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain DUF547 PF04784.14 GBG77823.1 - 0.036 14.1 0.0 0.081 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF547 Chromo PF00385.24 GBG77823.1 - 0.081 12.8 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG77823.1 - 0.099 12.3 0.0 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) SpoIIP PF07454.11 GBG77824.1 - 0.33 10.4 15.5 0.37 10.2 15.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 GBG77824.1 - 0.76 9.9 4.7 0.88 9.7 4.7 1.2 1 0 0 1 1 1 0 DDHD domain CCSAP PF15748.5 GBG77824.1 - 0.81 9.8 16.7 0.91 9.6 16.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 GBG77824.1 - 5.1 5.8 18.9 5.4 5.7 18.9 1.0 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG77824.1 - 5.5 5.1 48.2 6 5.0 48.2 1.1 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 GBG77824.1 - 9.7 6.0 20.2 13 5.6 20.2 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein rve PF00665.26 GBG77825.1 - 4.1e-15 56.0 0.0 9.3e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG77825.1 - 1.3e-07 32.1 0.0 1e-06 29.2 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77825.1 - 0.0003 21.4 0.0 0.00087 19.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG77825.1 - 0.0015 18.7 0.1 0.011 16.0 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein DUF1758 PF05585.12 GBG77825.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF1564 PF07600.11 GBG77825.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) gag-asp_proteas PF13975.6 GBG77826.1 - 2.6e-07 31.1 0.1 6.1e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77826.1 - 1.5e-05 25.5 0.2 5e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG77826.1 - 0.00088 19.1 0.1 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG77826.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease cNMP_binding PF00027.29 GBG77826.1 - 0.13 12.4 0.0 0.97 9.5 0.0 2.3 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain zf-CCHC PF00098.23 GBG77826.1 - 0.48 10.6 1.9 1.1 9.4 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG77830.1 - 8.6e-23 81.0 0.1 1.3e-22 80.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG77830.1 - 0.00062 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF2232 PF09991.9 GBG77831.1 - 3.1e-11 43.0 5.7 3.1e-11 43.0 5.7 1.8 1 1 1 2 2 2 1 Predicted membrane protein (DUF2232) IclR PF01614.18 GBG77832.1 - 0.37 10.6 7.0 0.53 10.1 2.5 2.5 2 0 0 2 2 2 0 Bacterial transcriptional regulator PCEMA1 PF07418.11 GBG77832.1 - 1.1 8.7 15.1 0.78 9.2 14.0 1.2 1 1 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 PRTP PF01366.18 GBG77832.1 - 1.6 6.7 7.8 1.9 6.4 7.8 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RT_RNaseH_2 PF17919.1 GBG77833.1 - 2.7e-31 107.5 0.0 9.9e-31 105.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77833.1 - 7.8e-31 106.5 0.0 2.6e-30 104.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77833.1 - 2e-18 66.3 0.7 2e-18 66.3 0.7 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG77833.1 - 0.0029 17.8 0.1 0.0081 16.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG77833.1 - 0.1 12.2 0.0 0.1 12.2 0.0 3.6 3 1 1 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG77836.1 - 4.1e-28 98.4 0.1 6.1e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77836.1 - 6.4e-22 77.5 0.0 3.3e-21 75.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77836.1 - 2.4e-21 76.0 0.0 7.3e-21 74.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77836.1 - 1e-15 57.5 0.3 2.6e-15 56.3 0.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG77836.1 - 6.9e-10 39.2 0.0 2.3e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG77836.1 - 6.8e-06 26.6 0.0 2e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77836.1 - 1.1e-05 26.0 0.0 2.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG77836.1 - 1.8e-05 24.5 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG77836.1 - 0.00022 21.0 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Sel1 PF08238.12 GBG77837.1 - 1.6e-18 66.7 4.7 0.0011 19.5 0.0 6.2 6 0 0 6 6 6 5 Sel1 repeat RT_RNaseH_2 PF17919.1 GBG77839.1 - 1.1e-22 80.0 0.0 2e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77839.1 - 3e-20 72.5 0.0 6.3e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77839.1 - 7.6e-10 39.0 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG77839.1 - 0.016 15.0 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 GBG77839.1 - 0.13 12.9 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CDC45 PF02724.14 GBG77840.1 - 0.021 13.2 14.1 0.024 12.9 14.1 1.0 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG77840.1 - 0.063 12.6 16.4 0.074 12.4 16.4 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GBG77840.1 - 0.069 11.9 1.4 0.07 11.9 1.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG77840.1 - 0.17 10.0 14.8 0.2 9.9 14.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG77840.1 - 0.24 10.8 5.4 0.29 10.5 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIF_alpha PF05793.12 GBG77840.1 - 0.59 8.7 21.5 0.73 8.4 21.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 GBG77840.1 - 0.97 8.8 19.2 1.1 8.6 19.2 1.1 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 GBG77840.1 - 1 9.1 7.8 1.4 8.7 7.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC106 PF15794.5 GBG77840.1 - 1.8 8.2 11.1 2.5 7.8 11.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Nop53 PF07767.11 GBG77840.1 - 2.2 7.6 19.6 2.8 7.2 19.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RRN3 PF05327.11 GBG77840.1 - 3.1 6.3 10.4 3.8 6.0 10.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pes-10 PF07149.11 GBG77840.1 - 4.3 6.3 16.7 6.2 5.8 16.7 1.1 1 0 0 1 1 1 0 Pes-10 Presenilin PF01080.17 GBG77840.1 - 8 5.1 11.7 10 4.8 11.7 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 GBG77840.1 - 8.2 5.2 10.1 9.7 4.9 10.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 GBG77840.1 - 9 4.3 8.5 11 4.0 8.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4342 PF14242.6 GBG77841.1 - 1.5 8.8 4.2 2.7 8.1 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) RVT_1 PF00078.27 GBG77842.1 - 0.00043 19.9 0.0 0.0008 19.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG77842.1 - 0.012 15.6 2.4 0.032 14.3 2.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Pox_Ag35 PF03286.14 GBG77843.1 - 0.21 11.3 16.7 0.39 10.5 16.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 GBG77843.1 - 1.8 8.3 26.9 2.9 7.5 26.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG77843.1 - 9.2 4.3 31.5 12 4.0 31.5 1.1 1 0 0 1 1 1 0 Nop14-like family Sel1 PF08238.12 GBG77844.1 - 6.2e-16 58.5 2.2 0.21 12.3 0.0 6.1 6 0 0 6 6 6 5 Sel1 repeat Dimer_Tnp_hAT PF05699.14 GBG77845.1 - 7e-09 35.4 0.1 1.6e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Integrase_H2C2 PF17921.1 GBG77846.1 - 1.9e-18 66.3 0.2 1.9e-18 66.3 0.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG77846.1 - 8.2e-15 55.0 0.0 1.8e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG77846.1 - 0.045 14.0 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG77847.1 - 0.015 15.5 0.4 0.13 12.5 0.1 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein ACT_3 PF10000.9 GBG77847.1 - 0.18 11.7 0.6 0.78 9.7 0.0 2.3 3 0 0 3 3 3 0 ACT domain Pro-rich PF15240.6 GBG77847.1 - 0.2 11.9 4.4 0.34 11.2 4.4 1.2 1 0 0 1 1 1 0 Proline-rich zf-CCHC_2 PF13696.6 GBG77847.1 - 0.48 10.3 2.0 0.8 9.6 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle PQQ PF01011.21 GBG77851.1 - 0.092 12.7 0.1 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 PQQ enzyme repeat DUF4360 PF14273.6 GBG77852.1 - 6.2e-36 123.9 0.0 8.3e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RskA PF10099.9 GBG77852.1 - 0.03 14.6 0.1 0.044 14.1 0.1 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DNA_methylase PF00145.17 GBG77853.1 - 0.12 11.7 0.0 0.9 8.8 0.0 1.9 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase DUF4360 PF14273.6 GBG77854.1 - 3.4e-33 115.0 0.0 4.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) zf-RVT PF13966.6 GBG77854.1 - 1.2e-09 38.8 2.8 2.3e-09 37.9 2.8 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RskA PF10099.9 GBG77854.1 - 0.032 14.5 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4360 PF14273.6 GBG77856.1 - 3.4e-46 157.4 0.0 3.8e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Cm_res_leader PF08077.11 GBG77856.1 - 0.17 12.0 1.9 4.5 7.7 0.1 3.0 2 0 0 2 2 2 0 Chloramphenicol resistance gene leader peptide GldM_N PF12081.8 GBG77859.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 2 0 0 2 2 2 0 GldM N-terminal domain DUF659 PF04937.15 GBG77860.1 - 1.6e-27 96.3 0.0 7.5e-15 55.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) DUF4360 PF14273.6 GBG77861.1 - 1.8e-43 148.5 0.0 2.4e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DDE_Tnp_4 PF13359.6 GBG77862.1 - 3.8e-28 98.2 0.0 8e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77862.1 - 5.5e-10 39.2 0.0 8.5e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77862.1 - 0.019 14.7 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Beach PF02138.18 GBG77862.1 - 0.24 10.8 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 Beige/BEACH domain DUF4360 PF14273.6 GBG77863.1 - 1.7e-36 125.7 0.0 2.9e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG77866.1 - 6.4e-26 91.3 0.0 7.4e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG77869.1 - 1e-41 142.8 0.0 1.2e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PROL5-SMR PF15621.6 GBG77869.1 - 0.072 13.6 1.2 0.11 13.0 0.2 1.8 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF4360 PF14273.6 GBG77870.1 - 5.5e-39 133.9 0.0 6.3e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PROL5-SMR PF15621.6 GBG77870.1 - 0.044 14.3 0.7 0.096 13.2 0.1 1.8 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family LRR_4 PF12799.7 GBG77872.1 - 3.2e-05 24.2 3.8 3.2 8.3 0.0 6.7 5 2 2 7 7 7 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG77872.1 - 9.8 6.5 12.4 7.5 6.9 0.0 6.1 9 0 0 9 9 9 0 Leucine Rich repeat RVT_1 PF00078.27 GBG77874.1 - 3e-26 92.3 0.1 4.9e-26 91.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77874.1 - 1.3e-23 82.9 0.0 2.8e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77874.1 - 5.8e-23 81.2 0.0 1.3e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TcdA_TcdB PF12919.7 GBG77875.1 - 0.023 14.0 0.0 0.079 12.2 0.0 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Retrotrans_gag PF03732.17 GBG77877.1 - 3.6e-06 27.2 0.0 1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein EMC1_C PF07774.13 GBG77877.1 - 0.31 10.7 0.9 0.54 9.9 0.9 1.3 1 0 0 1 1 1 0 ER membrane protein complex subunit 1, C-terminal Sarcoglycan_1 PF04790.13 GBG77877.1 - 0.64 9.3 3.6 1.1 8.5 3.6 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein DUF2236 PF09995.9 GBG77878.1 - 5.7e-36 124.8 4.7 8e-36 124.3 4.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DMRT-like PF15791.5 GBG77878.1 - 0.0063 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Doublesex-and mab-3-related transcription factor C1 and C2 AP2 PF00847.20 GBG77878.1 - 0.019 15.2 0.0 0.083 13.1 0.0 1.9 2 0 0 2 2 2 0 AP2 domain DUF659 PF04937.15 GBG77880.1 - 2.1e-33 115.3 0.1 4.1e-33 114.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zinc_ribbon_5 PF13719.6 GBG77880.1 - 0.16 11.7 0.5 0.48 10.2 0.5 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DUF2236 PF09995.9 GBG77881.1 - 4.4e-41 141.6 5.3 8.6e-41 140.6 5.3 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DBD_Tnp_Mut PF03108.15 GBG77881.1 - 0.00012 22.0 0.2 0.00038 20.4 0.0 2.0 2 0 0 2 2 2 1 MuDR family transposase RVT_1 PF00078.27 GBG77882.1 - 0.02 14.4 0.0 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pyridoxal_deC PF00282.19 GBG77883.1 - 1.8e-84 283.6 0.0 2.2e-84 283.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain gag-asp_proteas PF13975.6 GBG77884.1 - 3.5e-08 33.9 0.0 7.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77884.1 - 7.3e-05 23.3 0.0 0.00018 22.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG77884.1 - 0.00037 20.3 0.2 0.00061 19.6 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG77884.1 - 0.012 15.9 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease TMEM171 PF15471.6 GBG77885.1 - 0.99 8.3 2.7 1.4 7.9 2.7 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 BUD22 PF09073.10 GBG77885.1 - 2.8 7.2 11.4 3.3 7.0 11.4 1.2 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 GBG77885.1 - 10 5.2 6.0 15 4.6 6.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pyridoxal_deC PF00282.19 GBG77886.1 - 8.4e-96 320.9 0.0 1.1e-95 320.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain RVT_1 PF00078.27 GBG77888.1 - 7.3e-24 84.5 0.1 5.2e-22 78.5 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77888.1 - 3e-17 62.5 0.0 6.7e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77888.1 - 0.00011 22.5 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG77890.1 - 1.3e-20 73.8 0.0 2.3e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG77891.1 - 1.7e-20 73.5 0.1 3.4e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77891.1 - 2.1e-15 56.6 0.9 4.6e-15 55.5 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG77891.1 - 4.2e-13 49.5 0.0 1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77891.1 - 3.7e-07 30.1 0.0 9.4e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG77891.1 - 0.00035 20.4 0.0 0.00078 19.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG77891.1 - 0.019 15.2 0.1 0.055 13.7 0.1 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG77893.1 - 3.6e-31 108.0 0.0 4.9e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG77893.1 - 5.7e-12 45.7 0.0 9.5e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG77893.1 - 0.021 14.5 1.8 5.8 6.5 0.8 2.5 2 1 0 2 2 2 0 Transposase DDE domain Toxin_YhaV PF11663.8 GBG77893.1 - 0.13 12.3 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system Metallophos_2 PF12850.7 GBG77895.1 - 0.049 13.8 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DEK_C PF08766.11 GBG77896.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain RT_RNaseH_2 PF17919.1 GBG77898.1 - 7.6e-29 99.7 0.0 1.5e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77898.1 - 2.3e-27 95.3 0.0 4.9e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77898.1 - 2.1e-18 66.1 0.7 5.1e-18 64.9 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77898.1 - 2.3e-14 53.6 0.0 5.9e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG77898.1 - 0.00023 21.3 0.7 0.0005 20.2 0.1 1.9 2 0 0 2 2 2 1 H2C2 zinc finger GerA PF03323.13 GBG77898.1 - 0.12 10.8 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein RNA_pol_3_Rpc31 PF11705.8 GBG77898.1 - 1.5 9.0 11.5 2.8 8.1 11.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RVT_1 PF00078.27 GBG77899.1 - 2e-10 40.6 0.0 3.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sigma70_ner PF04546.13 GBG77899.1 - 0.00098 19.1 5.8 0.0013 18.6 5.8 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region BSP_II PF05432.11 GBG77899.1 - 0.0014 18.4 16.5 0.0018 18.1 16.5 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) GreA_GreB PF01272.19 GBG77899.1 - 0.0065 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term Myc_N PF01056.18 GBG77899.1 - 0.0078 16.2 7.8 0.013 15.5 7.8 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Nop14 PF04147.12 GBG77899.1 - 0.032 12.5 15.9 0.041 12.1 15.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG77899.1 - 0.16 10.3 20.1 0.21 9.8 20.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Mif2_N PF15624.6 GBG77899.1 - 0.23 12.1 8.8 0.34 11.6 8.8 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal RNA_pol_Rpc4 PF05132.14 GBG77899.1 - 0.31 11.4 5.6 0.67 10.4 5.6 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 PI3K_1B_p101 PF10486.9 GBG77899.1 - 0.51 8.0 4.8 0.66 7.7 4.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 GBG77899.1 - 0.67 8.0 15.6 0.91 7.5 15.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 GBG77899.1 - 1.6 8.9 8.4 3 8.0 8.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC27 PF09507.10 GBG77899.1 - 2.5 7.4 18.3 3.4 7.0 18.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sin_N PF04801.13 GBG77899.1 - 3 7.0 11.1 4.2 6.5 11.1 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region RR_TM4-6 PF06459.12 GBG77899.1 - 3.1 7.6 15.8 4.5 7.0 15.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Astro_capsid_p PF12226.8 GBG77899.1 - 3.3 6.8 9.1 4.7 6.3 9.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 GBG77899.1 - 3.5 6.9 12.5 5.8 6.1 12.5 1.3 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 GBG77899.1 - 4.7 6.1 4.9 6.3 5.7 4.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) XAP5 PF04921.14 GBG77899.1 - 6.3 6.5 14.9 9.4 6.0 14.9 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Sporozoite_P67 PF05642.11 GBG77899.1 - 7.7 4.5 8.3 11 4.0 8.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 GBG77899.1 - 8 6.9 15.5 13 6.2 14.4 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Paf1 PF03985.13 GBG77899.1 - 8.5 5.3 22.1 14 4.6 22.1 1.2 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 GBG77899.1 - 8.9 5.6 17.6 14 5.0 17.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT LRR_4 PF12799.7 GBG77901.1 - 1.5e-06 28.4 4.7 5.2 7.6 0.0 7.3 6 3 2 8 8 8 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG77901.1 - 1.8e-05 24.5 0.1 6.4e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG77901.1 - 0.0046 16.8 0.1 0.0046 16.8 0.1 3.0 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.7 GBG77903.1 - 1e-08 35.3 0.1 4.3 7.9 0.0 5.9 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG77903.1 - 1.3 9.3 4.9 32 4.9 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich repeat DUF659 PF04937.15 GBG77904.1 - 2e-21 76.5 0.0 5.6e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG77904.1 - 2e-08 33.9 0.4 6.1e-08 32.3 0.4 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LRR_4 PF12799.7 GBG77905.1 - 2.1e-09 37.5 0.0 5 7.7 0.0 5.8 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG77905.1 - 3.5e-05 23.6 0.1 8.4e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG77905.1 - 0.0014 18.5 0.2 0.0014 18.5 0.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 GBG77905.1 - 0.095 12.8 0.5 1.2e+02 3.2 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich repeat F-box PF00646.33 GBG77907.1 - 0.0031 17.4 3.0 0.0066 16.3 0.2 3.2 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 GBG77907.1 - 0.0065 16.3 0.0 0.025 14.5 0.0 2.1 1 0 0 1 1 1 1 F-box-like CENP-K PF11802.8 GBG77909.1 - 0.00018 21.1 4.8 0.00031 20.4 4.8 1.3 1 0 0 1 1 1 1 Centromere-associated protein K Retrotrans_gag PF03732.17 GBG77909.1 - 0.0029 17.8 0.2 0.0029 17.8 0.2 2.9 4 0 0 4 4 4 1 Retrotransposon gag protein DUF3499 PF12005.8 GBG77909.1 - 0.76 10.4 13.6 0.78 10.4 4.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3499) Jnk-SapK_ap_N PF09744.9 GBG77909.1 - 0.8 9.9 10.8 0.09 13.0 1.9 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Mt_ATP-synt_B PF05405.14 GBG77909.1 - 5.1 6.7 11.7 4.9 6.7 10.0 1.9 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FmiP_Thoc5 PF09766.9 GBG77909.1 - 7.7 5.7 14.4 0.084 12.1 4.9 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 RVT_1 PF00078.27 GBG77910.1 - 1.4e-27 96.7 0.1 2.6e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77910.1 - 5.1e-23 81.0 0.0 9.4e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77910.1 - 1.8e-20 73.2 0.0 3.2e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77910.1 - 4.2e-14 52.4 1.9 1.3e-13 50.8 0.7 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG77910.1 - 1.9e-05 24.8 0.0 5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG77910.1 - 0.00012 22.0 0.0 0.0003 20.6 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1018 PF06252.12 GBG77910.1 - 0.76 10.8 2.7 69 4.5 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1018) DUF1018 PF06252.12 GBG77911.1 - 0.13 13.3 4.7 7.7 7.5 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) DUF1891 PF09004.10 GBG77911.1 - 0.2 11.3 0.7 0.36 10.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) RT_RNaseH_2 PF17919.1 GBG77912.1 - 2.1e-34 117.5 0.0 3.9e-34 116.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77912.1 - 5.1e-31 107.1 0.1 9.7e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77912.1 - 5.2e-30 104.6 0.1 1.1e-29 103.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77912.1 - 2.3e-17 62.8 0.2 7.3e-17 61.2 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG77912.1 - 1.1e-14 54.6 0.1 5.1e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG77912.1 - 2.5e-06 27.9 0.0 6.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG77912.1 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77912.1 - 0.0004 21.0 0.0 0.00089 19.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG77912.1 - 0.0021 17.8 0.1 0.0088 15.8 0.0 1.9 2 0 0 2 2 2 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG77912.1 - 0.019 15.1 0.0 0.072 13.3 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger DUF659 PF04937.15 GBG77913.1 - 2e-31 108.9 0.0 3.4e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG77913.1 - 0.00075 19.2 2.4 0.00077 19.2 0.6 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zinc_ribbon_5 PF13719.6 GBG77913.1 - 0.017 14.9 0.1 0.043 13.6 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain TFIIA PF03153.13 GBG77913.1 - 0.53 10.2 36.2 1.1 9.2 29.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 GBG77914.1 - 7.6e-40 134.6 0.2 7.3e-17 61.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG77914.1 - 1.4e-07 31.5 0.0 0.0016 18.5 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GBG77914.1 - 0.0086 16.1 0.0 0.093 12.7 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 GBG77914.1 - 0.035 13.9 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 GBG77914.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif RL PF17797.1 GBG77914.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 RL domain Spem1 PF15670.5 GBG77915.1 - 3.1 7.3 21.6 3.8 7.0 21.6 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 FAM60A PF15396.6 GBG77915.1 - 5.8 6.9 28.5 7.4 6.5 28.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 GBG77915.1 - 7.2 5.5 26.2 7.9 5.4 26.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 EF-hand_7 PF13499.6 GBG77916.1 - 0.008 16.6 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair 2OG-FeII_Oxy_2 PF13532.6 GBG77917.1 - 0.042 14.0 0.4 0.1 12.8 0.4 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4392 PF14336.6 GBG77917.1 - 0.054 12.9 0.4 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Phage_lysozyme PF00959.19 GBG77917.1 - 0.13 12.7 0.1 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Phage lysozyme Es2 PF09751.9 GBG77917.1 - 0.54 9.9 16.5 0.87 9.3 16.5 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 RT_RNaseH_2 PF17919.1 GBG77918.1 - 1.2e-27 95.8 0.0 3.4e-27 94.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77918.1 - 1.7e-25 89.3 0.1 4.4e-25 88.0 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77918.1 - 2.7e-11 43.4 0.0 5.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77918.1 - 6e-08 32.7 1.6 1.1e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG77918.1 - 2.3e-07 30.6 0.0 6.7e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG77918.1 - 8.9e-06 26.2 0.0 0.00011 22.7 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77918.1 - 6.4e-05 23.5 0.0 0.00034 21.2 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease CCD48 PF15799.5 GBG77918.1 - 0.0016 16.8 2.0 0.0029 16.0 2.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 Asp_protease PF09668.10 GBG77918.1 - 0.003 17.3 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease EF-hand_8 PF13833.6 GBG77918.1 - 0.02 14.8 0.2 0.048 13.5 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair DUF2385 PF09539.10 GBG77918.1 - 0.12 12.9 0.3 2.4 8.7 0.0 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF2385) GvpL_GvpF PF06386.11 GBG77918.1 - 9.8 6.0 7.6 5.8 6.8 4.9 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF AbiEi_3_N PF17194.4 GBG77920.1 - 0.016 15.3 0.0 0.23 11.5 0.1 2.6 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Retrotrans_gag PF03732.17 GBG77920.1 - 0.11 12.8 0.6 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG77921.1 - 1.8e-34 119.2 0.1 3.1e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77921.1 - 1.6e-30 105.5 0.0 3.6e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77921.1 - 1.7e-30 105.0 0.0 5.4e-30 103.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77921.1 - 3e-06 27.2 0.1 7.5e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Cas_DxTHG PF09455.10 GBG77921.1 - 0.015 14.9 3.7 0.045 13.3 3.7 1.7 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Phage_GPO PF05929.11 GBG77921.1 - 5.2 6.6 17.8 1 9.0 0.0 2.5 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Peptidase_S46 PF10459.9 GBG77921.1 - 7.3 5.1 11.7 17 3.9 10.6 1.8 2 0 0 2 2 2 0 Peptidase S46 Kazal_2 PF07648.15 GBG77922.1 - 1.5e-15 57.1 39.8 1.2e-06 28.6 2.2 4.3 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 GBG77922.1 - 5.4e-13 48.7 43.8 4.3e-07 29.8 7.4 4.8 4 1 2 6 6 6 3 Kazal-type serine protease inhibitor domain FOLN PF09289.10 GBG77922.1 - 0.07 13.3 0.2 0.07 13.3 0.2 3.8 3 0 0 3 3 3 0 Follistatin/Osteonectin-like EGF domain Sugar_tr PF00083.24 GBG77923.1 - 1.7e-109 366.7 43.9 9.2e-88 295.1 2.2 4.3 4 0 0 4 4 4 3 Sugar (and other) transporter MFS_1 PF07690.16 GBG77923.1 - 2.9e-67 227.1 76.0 2.1e-32 112.5 11.1 4.3 3 1 1 4 4 4 4 Major Facilitator Superfamily TRI12 PF06609.13 GBG77923.1 - 8.8e-07 27.7 1.3 8.8e-07 27.7 1.3 2.5 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) UL42 PF17638.2 GBG77923.1 - 0.19 11.7 1.6 0.51 10.3 0.1 2.3 2 0 0 2 2 2 0 HCMV UL42 Rick_17kDa_Anti PF05433.15 GBG77923.1 - 0.55 10.1 8.9 0.8 9.6 0.5 3.7 3 0 0 3 3 3 0 Glycine zipper 2TM domain DUF2048 PF09752.9 GBG77924.1 - 9.7e-103 343.9 0.0 1.8e-102 343.1 0.0 1.4 1 1 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 GBG77924.1 - 0.00019 21.1 0.0 0.097 12.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 GBG77924.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SQS_PSY PF00494.19 GBG77925.1 - 4e-42 144.5 0.1 8.1e-42 143.5 0.1 1.5 1 0 0 1 1 1 1 Squalene/phytoene synthase LigT_PEase PF02834.16 GBG77925.1 - 0.039 14.1 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 LigT like Phosphoesterase SecY PF00344.20 GBG77926.1 - 1.9e-56 191.6 7.4 2.5e-56 191.2 7.4 1.2 1 0 0 1 1 1 1 SecY translocase SPX PF03105.19 GBG77926.1 - 0.16 11.9 4.4 0.22 11.4 4.4 1.1 1 0 0 1 1 1 0 SPX domain rve PF00665.26 GBG77928.1 - 2.6e-10 40.5 0.3 9e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG77928.1 - 3.8e-07 30.1 0.5 8.6e-07 29.0 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG77928.1 - 0.0019 17.9 0.2 0.1 12.3 0.2 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG77928.1 - 0.0037 17.5 0.4 0.11 12.8 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG77928.1 - 0.13 11.6 7.2 0.31 10.4 7.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 GBG77928.1 - 0.91 9.7 2.9 2.8 8.1 2.9 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Integrase_H2C2 PF17921.1 GBG77929.1 - 6.9e-19 67.7 0.4 2.3e-18 66.0 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG77929.1 - 3.2e-16 59.5 0.0 7.8e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77929.1 - 2.6e-10 40.2 0.0 5.7e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77929.1 - 3e-09 37.1 0.0 9.2e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG77929.1 - 0.024 14.8 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Ribosomal_L11_N PF03946.14 GBG77930.1 - 7.2e-22 77.0 0.2 1.2e-21 76.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 GBG77930.1 - 1.1e-16 61.0 1.1 1.5e-16 60.7 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain PAP_fibrillin PF04755.12 GBG77931.1 - 0.00029 20.9 0.4 0.17 11.8 0.4 2.8 1 1 0 1 1 1 1 PAP_fibrillin Integrase_H2C2 PF17921.1 GBG77934.1 - 3.4e-13 49.5 0.0 7.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77934.1 - 1.2e-08 35.1 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG77934.1 - 0.00029 21.4 0.0 0.00078 20.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG77934.1 - 0.0024 18.5 0.0 0.0059 17.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG77934.1 - 0.12 12.7 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Lipoprotein_18 PF06804.11 GBG77935.1 - 0.031 13.3 0.8 0.048 12.7 0.8 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein RT_RNaseH_2 PF17919.1 GBG77936.1 - 1.1e-30 105.6 0.0 2.8e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77936.1 - 4.9e-30 103.9 0.0 1.6e-29 102.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77936.1 - 8.8e-18 64.2 1.5 2.1e-17 63.0 1.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG77936.1 - 2.4e-15 56.7 0.0 4.4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG77936.1 - 0.00057 20.0 0.1 0.0016 18.6 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF5401 PF17380.2 GBG77936.1 - 7.6 4.5 48.1 11 3.9 48.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Nucleotid_trans PF03407.16 GBG77937.1 - 4.7e-33 115.0 0.0 1e-31 110.6 0.0 2.3 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Myb_DNA-bind_4 PF13837.6 GBG77939.1 - 3.5e-06 27.3 1.3 1.5e-05 25.3 0.2 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Nha1_C PF08619.10 GBG77940.1 - 0.032 13.4 4.3 0.05 12.8 4.3 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus OAD_gamma PF04277.13 GBG77940.1 - 0.098 13.3 3.3 1.2 9.8 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Claudin_2 PF13903.6 GBG77940.1 - 0.12 12.1 0.0 10 5.8 0.0 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2075 PF09848.9 GBG77940.1 - 0.61 9.3 4.4 1.4 8.0 4.5 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) LapA_dom PF06305.11 GBG77940.1 - 8.2 6.3 5.3 22 5.0 1.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF659 PF04937.15 GBG77941.1 - 7.1e-30 103.9 0.2 1.2e-29 103.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG77941.1 - 0.00029 20.6 0.3 0.00069 19.4 0.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ABC_membrane PF00664.23 GBG77942.1 - 3.1e-58 197.6 17.4 5.8e-36 124.5 1.6 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 GBG77942.1 - 2.4e-49 167.4 0.0 8e-27 94.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GBG77942.1 - 6e-07 29.1 0.4 0.65 9.4 0.0 4.2 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GBG77942.1 - 8.8e-07 29.0 0.2 2.6 7.8 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GBG77942.1 - 3.4e-06 27.1 1.7 0.078 13.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 GBG77942.1 - 3.6e-05 23.9 2.6 0.008 16.3 0.2 2.6 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 GBG77942.1 - 5.1e-05 23.2 0.2 0.032 14.1 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GBG77942.1 - 5.7e-05 22.8 0.7 0.072 12.8 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG77942.1 - 0.00034 21.0 0.7 0.12 12.7 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain MliC PF09864.9 GBG77942.1 - 0.0034 17.3 0.0 0.0092 15.9 0.0 1.7 1 0 0 1 1 1 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme AAA_23 PF13476.6 GBG77942.1 - 0.02 15.4 0.2 5.3 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 GBG77942.1 - 0.049 12.9 0.9 2.4 7.4 0.3 2.4 2 0 0 2 2 2 0 AIG1 family Zeta_toxin PF06414.12 GBG77942.1 - 0.088 12.1 0.2 1 8.6 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 GBG77942.1 - 1.2 9.2 5.4 5.1 7.1 0.3 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 GBG77942.1 - 2.2 7.8 4.2 2.7 7.6 0.3 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Retrotrans_gag PF03732.17 GBG77943.1 - 0.017 15.4 5.3 0.018 15.3 0.1 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein FWWh PF14922.6 GBG77943.1 - 0.049 13.6 0.9 2.1 8.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function Methyltransf_21 PF05050.12 GBG77944.1 - 1.3e-07 31.8 0.0 1.8e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain zf-CCHC PF00098.23 GBG77945.1 - 3.3e-07 30.1 5.4 3.3e-07 30.1 5.4 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG77945.1 - 0.057 13.1 3.1 0.15 11.8 3.1 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG77945.1 - 0.33 10.8 7.0 0.21 11.4 2.7 2.5 2 0 0 2 2 2 0 Zinc knuckle TPR_MLP1_2 PF07926.12 GBG77946.1 - 0.00056 20.0 43.0 0.068 13.2 21.9 4.2 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein APC_N_CC PF16689.5 GBG77946.1 - 0.037 14.1 0.5 0.037 14.1 0.5 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Filament PF00038.21 GBG77946.1 - 0.58 9.7 35.2 0.26 10.8 15.3 2.3 1 1 1 2 2 2 0 Intermediate filament protein MetOD2 PF18548.1 GBG77946.1 - 0.64 10.2 14.7 0.13 12.4 1.4 3.5 2 2 1 3 3 3 0 Metanogen output domain 2 ZapB PF06005.12 GBG77946.1 - 1 9.9 42.7 1 9.8 6.7 4.8 2 2 2 4 4 4 0 Cell division protein ZapB MbeD_MobD PF04899.12 GBG77946.1 - 1.4 9.1 16.0 0.3 11.2 0.3 3.6 2 1 1 3 3 3 0 MbeD/MobD like Fib_alpha PF08702.10 GBG77946.1 - 3.8 7.7 15.4 0.35 11.1 6.2 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 GBG77946.1 - 8.6 6.8 10.6 43 4.6 0.2 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Radical_SAM PF04055.21 GBG77947.1 - 3.2e-18 66.6 0.0 6.2e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 GBG77947.1 - 6.6e-14 51.8 0.0 3.2e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 RT_RNaseH PF17917.1 GBG77948.1 - 7.4e-23 80.8 0.0 3.2e-22 78.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77948.1 - 1.6e-22 79.4 0.0 5.3e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG77948.1 - 0.002 18.4 0.0 0.013 15.7 0.0 2.4 1 0 0 1 1 1 1 Retrotransposon gag protein WTX PF09422.10 GBG77948.1 - 0.067 12.3 6.3 0.1 11.6 6.3 1.2 1 0 0 1 1 1 0 WTX protein DUF5523 PF17661.1 GBG77948.1 - 1.3 8.7 5.4 2.2 7.9 5.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) TolA_bind_tri PF16331.5 GBG77948.1 - 2.9 8.0 11.0 0.25 11.4 6.0 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation TRAM PF01938.20 GBG77949.1 - 0.0015 18.4 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 TRAM domain DUF908 PF06012.12 GBG77949.1 - 0.16 11.4 0.3 0.18 11.2 0.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) AAA_16 PF13191.6 GBG77950.1 - 0.0055 17.1 0.1 0.024 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GBG77950.1 - 0.057 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF3142 PF11340.8 GBG77950.1 - 0.068 13.0 0.2 0.18 11.6 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3142) AAA_14 PF13173.6 GBG77950.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GBG77950.1 - 0.16 11.9 0.0 0.74 9.7 0.0 2.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea UCH PF00443.29 GBG77951.1 - 3.4e-35 121.8 0.0 4.4e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GBG77951.1 - 9.3e-15 54.7 5.9 9.3e-15 54.7 5.9 2.4 3 0 0 3 3 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GBG77951.1 - 2.3e-12 47.2 0.0 3.2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cwf_Cwc_15 PF04889.12 GBG77951.1 - 0.0066 16.2 19.3 0.01 15.6 19.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG77951.1 - 0.044 12.0 12.1 0.061 11.5 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 GBG77951.1 - 0.28 11.1 9.0 0.45 10.4 9.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Mpp10 PF04006.12 GBG77951.1 - 0.28 9.6 10.2 0.38 9.1 10.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Peptidase_C98 PF15499.6 GBG77951.1 - 0.88 9.0 4.9 2.2 7.7 0.4 2.3 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CDC45 PF02724.14 GBG77951.1 - 1.2 7.3 12.9 1.8 6.8 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG77951.1 - 1.5 8.9 20.9 2.6 8.1 20.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GBG77951.1 - 1.5 8.1 15.3 2.3 7.6 15.3 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GBG77951.1 - 1.8 6.6 26.6 2.5 6.1 26.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 GBG77951.1 - 1.9 7.6 4.1 3 6.9 4.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.14 GBG77951.1 - 3.4 7.4 6.9 7 6.4 6.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Roughex PF06020.11 GBG77951.1 - 9.1 5.3 9.0 13 4.7 9.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein UCH PF00443.29 GBG77952.1 - 1.3e-54 185.4 0.0 1.7e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG77952.1 - 4e-21 75.9 0.0 2.2e-20 73.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GBG77952.1 - 5.1e-15 55.6 10.2 1.2e-14 54.3 5.9 3.0 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein YL1 PF05764.13 GBG77952.1 - 1.2e-05 25.6 7.6 1.9e-05 24.9 7.6 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GBG77952.1 - 0.0019 18.0 17.3 0.003 17.3 17.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG77952.1 - 0.068 11.4 14.5 0.095 10.9 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG77952.1 - 0.24 10.7 18.5 0.35 10.2 18.5 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 GBG77952.1 - 0.36 9.2 12.8 0.51 8.7 12.8 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG77952.1 - 0.72 9.2 16.1 1.1 8.7 16.1 1.1 1 0 0 1 1 1 0 SDA1 Peptidase_C98 PF15499.6 GBG77952.1 - 0.76 9.2 8.5 2.9 7.3 0.4 3.2 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DNA_pol_phi PF04931.13 GBG77952.1 - 2.8 5.9 26.5 4 5.4 26.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi eIF3_subunit PF08597.10 GBG77952.1 - 3.3 7.5 16.2 5.3 6.9 16.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Roughex PF06020.11 GBG77952.1 - 5.1 6.1 8.6 7.6 5.5 8.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PT-VENN PF04829.13 GBG77954.1 - 0.016 15.2 0.5 3.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif DUF389 PF04087.14 GBG77954.1 - 0.061 13.4 6.0 0.55 10.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF389) Mannosyl_trans2 PF04188.13 GBG77955.1 - 8.4e-12 45.1 0.0 1e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) KN17_SH3 PF18131.1 GBG77956.1 - 8e-06 25.9 3.6 76 3.5 0.0 7.0 1 1 7 9 9 9 0 KN17 SH3-like C-terminal domain PDZ PF00595.24 GBG77956.1 - 0.0015 18.9 8.0 15 6.0 0.1 5.0 2 2 3 5 5 5 2 PDZ domain Mucin-like PF16058.5 GBG77956.1 - 0.0074 16.3 0.0 0.38 10.9 0.0 2.5 1 1 2 3 3 3 2 Mucin-like CspB_prodomain PF18425.1 GBG77956.1 - 0.19 11.7 0.6 8.8 6.4 0.1 3.3 2 2 1 3 3 3 0 Csp protease B prodomain DUF1039 PF06287.11 GBG77956.1 - 5.4 7.5 10.7 22 5.6 0.1 5.8 5 3 3 9 9 9 0 Protein of unknown function (DUF1039) RT_RNaseH PF17917.1 GBG77957.1 - 5.6e-23 81.2 0.0 1.5e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77957.1 - 2.5e-22 78.8 0.0 2.1e-21 75.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77957.1 - 3.3e-17 62.3 0.6 1.4e-16 60.4 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG77957.1 - 7.3e-06 26.5 0.0 0.0013 19.4 0.0 2.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77957.1 - 2.9e-05 24.5 0.0 0.002 18.7 0.0 2.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG77957.1 - 0.00042 19.9 0.0 0.00076 19.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG77957.1 - 0.011 15.4 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease PIF1 PF05970.14 GBG77958.1 - 2.4e-56 191.5 0.0 3.8e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 GBG77958.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF659 PF04937.15 GBG77959.1 - 1.2e-18 67.5 0.0 1.8e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG77960.1 - 2.8e-18 66.1 0.0 7.5e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77960.1 - 3.1e-16 59.2 0.0 8.8e-16 57.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77960.1 - 1.6e-07 31.1 0.0 3.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG77961.1 - 1.1e-08 34.7 0.4 3.4e-08 33.2 0.4 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG77961.1 - 0.059 13.2 1.2 0.14 12.0 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG77961.1 - 0.11 12.2 0.4 0.26 11.1 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle PGBA_C PF15437.6 GBG77961.1 - 9.9 6.6 24.8 2.8 8.4 16.1 2.8 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal RVT_1 PF00078.27 GBG77962.1 - 1.3e-26 93.5 0.1 2.2e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77962.1 - 7.6e-15 54.8 0.4 9.7e-14 51.2 0.0 3.0 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG77962.1 - 1.5e-12 47.7 0.0 4.7e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG77962.1 - 0.00085 19.5 0.0 0.0044 17.2 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 GBG77963.1 - 6.5e-33 114.1 0.1 8.7e-29 100.6 0.0 2.5 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77963.1 - 7.7e-20 70.8 0.0 1.6e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77963.1 - 5.1e-10 39.6 0.0 1.4e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 GBG77963.1 - 9.7e-05 21.9 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG77963.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase zf-CCHC_6 PF15288.6 GBG77963.1 - 0.085 12.7 0.6 0.26 11.1 0.4 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG77963.1 - 2.5 8.3 8.5 0.44 10.7 4.1 2.1 2 0 0 2 2 2 0 Zinc knuckle RelE PF06296.12 GBG77965.1 - 0.06 13.5 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system DUF5568 PF17724.1 GBG77966.1 - 4.4 7.1 10.6 19 5.0 10.6 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5568) RT_RNaseH_2 PF17919.1 GBG77967.1 - 9.4e-60 198.9 0.1 5.6e-33 113.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77967.1 - 3.8e-46 155.7 0.3 8.3e-28 96.8 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77967.1 - 3e-33 115.2 0.0 5.3e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG77967.1 - 4.1e-18 65.2 0.1 1.1e-17 63.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77967.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG77967.1 - 0.085 13.1 0.0 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG77968.1 - 2.1e-42 143.2 0.1 2.2e-27 95.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77968.1 - 6.9e-30 103.4 1.1 2.1e-24 85.8 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77968.1 - 1.6e-12 47.4 0.3 4e-12 46.1 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG77968.1 - 0.0024 18.1 0.1 0.0068 16.6 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG77968.1 - 0.0068 16.7 0.0 0.024 14.9 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG77968.1 - 0.011 15.7 1.8 0.021 14.8 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG77968.1 - 1.5 9.0 4.9 2.8 8.2 4.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 GBG77969.1 - 1.7e-08 34.3 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77969.1 - 7.6e-08 32.8 0.0 2.7e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG77969.1 - 2.3e-06 27.6 0.1 6.6e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG77969.1 - 1.3e-05 25.7 0.0 4.2e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG77969.1 - 0.00041 20.3 4.0 0.025 14.7 1.0 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 GBG77970.1 - 0.0019 18.2 3.3 0.0045 17.0 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF2514 PF10721.9 GBG77970.1 - 0.52 10.3 9.8 0.99 9.4 8.7 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2514) DUF5320 PF17253.2 GBG77970.1 - 3.6 8.7 5.7 2 9.5 2.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) RT_RNaseH_2 PF17919.1 GBG77971.1 - 3.7e-42 142.4 0.2 1.8e-22 79.2 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77971.1 - 6.1e-38 130.5 6.5 6.3e-34 117.4 0.1 3.3 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77971.1 - 8.6e-37 125.6 0.2 1.4e-22 80.0 0.3 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77971.1 - 1.5e-31 108.2 2.6 2.3e-17 62.9 0.5 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG77971.1 - 3.6e-06 27.2 0.1 1.3e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG77971.1 - 0.058 13.6 0.0 0.44 10.8 0.0 2.5 2 0 0 2 2 2 0 H2C2 zinc finger TRF PF08558.10 GBG77971.1 - 0.092 12.3 0.1 13 5.3 0.0 3.0 3 0 0 3 3 3 0 Telomere repeat binding factor (TRF) Asp_protease_2 PF13650.6 GBG77971.1 - 0.1 13.2 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG77971.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 GBG77972.1 - 1.1e-26 92.8 0.0 2.5e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77972.1 - 6.8e-25 87.4 0.0 1.6e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77972.1 - 0.00029 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG77972.1 - 0.0011 18.2 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF3740 PF12548.8 GBG77972.1 - 0.64 10.5 4.2 6 7.3 0.5 2.4 2 0 0 2 2 2 0 Sulfatase protein RT_RNaseH PF17917.1 GBG77973.1 - 1.2e-27 96.3 0.2 4.1e-27 94.5 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77973.1 - 1.3e-24 86.2 0.0 3.4e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77973.1 - 8e-14 51.5 0.2 2.9e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG77973.1 - 0.0014 18.8 0.0 0.0051 17.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG77973.1 - 0.013 15.8 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG77973.1 - 0.014 15.6 0.0 0.042 14.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Cnl2_NKP2 PF09447.10 GBG77973.1 - 0.064 13.4 0.0 21 5.3 0.1 2.8 2 0 0 2 2 2 0 Cnl2/NKP2 family protein eIF-1a PF01176.19 GBG77973.1 - 0.069 13.0 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Chromo PF00385.24 GBG77973.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG77974.1 - 1.4e-29 102.0 0.0 2.4e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77974.1 - 4.8e-16 58.9 0.0 9.3e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77975.1 - 1.7e-23 82.5 0.0 3.8e-23 81.4 0.0 1.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77975.1 - 1.9e-23 82.7 0.0 3.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77975.1 - 0.0017 17.9 0.0 0.087 12.3 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG77976.1 - 0.082 13.0 3.1 0.13 12.4 3.1 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG77977.1 - 6.5e-28 97.8 0.3 2.2e-25 89.5 0.0 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77977.1 - 1.5e-23 82.7 0.0 3.4e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77977.1 - 9.6e-23 80.5 0.0 1.9e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG77977.1 - 2.9e-13 49.7 0.0 6.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG77977.1 - 4.2e-09 36.6 0.2 1.9e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG77977.1 - 1.3e-08 35.4 0.0 2.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG77977.1 - 2.2e-08 33.9 0.0 5.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG77977.1 - 6.5e-06 26.6 0.0 1.3e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77977.1 - 0.003 17.4 0.0 0.0086 15.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Tudor-knot PF11717.8 GBG77977.1 - 0.0038 17.1 0.0 0.0087 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Integrin_b_cyt PF08725.11 GBG77977.1 - 0.04 13.6 0.1 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain RT_RNaseH_2 PF17919.1 GBG77978.1 - 6.4e-40 135.2 1.7 3.9e-16 58.9 0.0 3.6 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77978.1 - 4.9e-38 129.6 7.0 3.6e-15 56.1 0.1 4.7 3 1 1 4 4 4 4 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG77978.1 - 1.1e-24 86.9 0.5 1.1e-13 51.4 0.0 3.3 3 0 0 3 3 3 2 Integrase core domain RVT_1 PF00078.27 GBG77978.1 - 9e-23 80.9 0.1 1.6e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG77978.1 - 4.3e-16 58.9 0.0 1.2e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG77978.1 - 2.1e-11 43.7 0.2 4.7e-11 42.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG77978.1 - 1.6e-10 41.1 4.1 0.034 14.4 0.1 5.4 5 0 0 5 5 5 3 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG77978.1 - 2.8e-10 40.7 0.0 1.3e-07 32.1 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77978.1 - 2.3e-08 34.5 0.0 5e-06 27.0 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG77978.1 - 0.0016 18.3 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease DUF1564 PF07600.11 GBG77978.1 - 0.081 12.6 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) TOBE_2 PF08402.10 GBG77978.1 - 0.12 12.5 0.1 15 5.8 0.0 3.0 2 0 0 2 2 2 0 TOBE domain Cep57_MT_bd PF06657.13 GBG77978.1 - 3.3 8.2 12.0 0.71 10.4 4.8 3.6 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF443 PF04276.12 GBG77980.1 - 0.0087 15.9 6.1 0.012 15.4 6.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF443) DUF2721 PF11026.8 GBG77980.1 - 0.017 15.0 8.0 0.03 14.2 8.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Wzy_C PF04932.15 GBG77980.1 - 0.018 14.7 0.1 0.041 13.5 0.0 1.5 1 1 1 2 2 2 0 O-Antigen ligase OPT PF03169.15 GBG77980.1 - 0.021 13.5 3.6 0.027 13.1 3.6 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Orf78 PF06024.12 GBG77980.1 - 0.023 15.0 2.8 0.023 15.0 2.8 2.4 1 1 1 2 2 1 0 Orf78 (ac78) DUF2207 PF09972.9 GBG77980.1 - 0.054 12.3 2.0 0.072 11.8 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4191 PF13829.6 GBG77980.1 - 0.068 12.5 7.8 0.12 11.7 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF454 PF04304.13 GBG77980.1 - 0.075 13.0 8.4 0.064 13.3 6.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF454) FA_desaturase PF00487.24 GBG77980.1 - 0.09 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase ETRAMP PF09716.10 GBG77980.1 - 0.11 12.6 6.5 0.09 12.8 2.8 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SUR7 PF06687.12 GBG77980.1 - 0.25 11.0 5.3 0.38 10.3 4.7 1.5 1 1 0 1 1 1 0 SUR7/PalI family DUF1676 PF07898.13 GBG77980.1 - 0.42 10.6 14.6 0.77 9.8 12.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1676) DUF805 PF05656.14 GBG77980.1 - 0.91 10.0 4.4 0.48 10.8 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF1129 PF06570.11 GBG77980.1 - 1 8.8 8.2 1.7 8.1 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) UL45 PF05473.12 GBG77980.1 - 3.4 7.2 7.5 0.19 11.4 1.7 1.8 1 1 1 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like LMF1 PF06762.14 GBG77980.1 - 3.5 6.6 5.7 5.4 6.0 5.7 1.3 1 0 0 1 1 1 0 Lipase maturation factor Peptidase_C48 PF02902.19 GBG77981.1 - 2.2e-12 47.3 0.1 4.1e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Gln-synt_N PF03951.19 GBG77981.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain ESF1 PF18209.1 GBG77981.1 - 2.8 7.9 5.5 2.3 8.2 0.2 2.8 2 0 0 2 2 2 0 Embryo surrounding factor 1 DUF3307 PF11750.8 GBG77982.1 - 0.089 12.9 0.6 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3307) Peptidase_C48 PF02902.19 GBG77983.1 - 8.2e-14 52.0 0.0 2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RVT_1 PF00078.27 GBG77984.1 - 1.3e-16 60.8 0.2 2.1e-16 60.1 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG77985.1 - 1.4 7.2 6.2 1.6 6.9 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein CCDC71L PF15374.6 GBG77986.1 - 0.087 12.1 3.1 0.12 11.6 3.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L zf-CCHC PF00098.23 GBG77987.1 - 8.8e-08 31.9 5.4 1.7e-07 31.0 5.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Metal_resist PF13801.6 GBG77987.1 - 0.017 15.3 0.5 0.017 15.3 0.5 2.0 1 1 0 2 2 2 0 Heavy-metal resistance zf-CCHC_5 PF14787.6 GBG77987.1 - 0.034 13.8 3.5 0.034 13.8 3.5 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF1110 PF06533.12 GBG77987.1 - 0.071 13.1 0.7 0.094 12.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) zf-CCHC_2 PF13696.6 GBG77987.1 - 0.13 12.1 4.2 0.11 12.3 2.7 1.6 2 0 0 2 2 2 0 Zinc knuckle Takusan PF04822.13 GBG77987.1 - 0.71 9.8 8.0 1.8 8.5 8.0 1.7 1 1 0 1 1 1 0 Takusan TAF4 PF05236.14 GBG77987.1 - 2.8 7.6 19.6 0.92 9.2 17.0 1.4 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family RT_RNaseH_2 PF17919.1 GBG77989.1 - 1.4e-27 95.6 0.0 5.3e-27 93.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77989.1 - 8e-26 90.9 0.3 3.1e-25 89.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG77989.1 - 1.6e-25 89.4 0.0 4.1e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Use1 PF09753.9 GBG77989.1 - 0.088 12.5 2.9 0.14 11.9 1.1 2.2 2 0 0 2 2 2 0 Membrane fusion protein Use1 NPV_P10 PF05531.12 GBG77989.1 - 0.18 12.3 0.3 3.4 8.2 0.3 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG77990.1 - 1.5e-25 90.1 0.0 3e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG77990.1 - 1.2e-20 73.4 0.0 2.9e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG77990.1 - 1.3e-10 41.5 0.0 4.3e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG77990.1 - 4.3e-10 39.5 0.0 8.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG77990.1 - 0.00024 21.7 0.0 0.00072 20.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG77990.1 - 0.025 15.1 0.0 0.058 14.0 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Endonuc-PvuII PF09225.10 GBG77990.1 - 0.14 11.9 0.1 8.6 6.1 0.0 2.8 3 0 0 3 3 3 0 Restriction endonuclease PvuII Vir_act_alpha_C PF10400.9 GBG77990.1 - 0.57 10.9 3.3 4.1 8.2 3.5 2.3 2 0 0 2 2 2 0 Virulence activator alpha C-term DUF4140 PF13600.6 GBG77990.1 - 0.69 10.4 6.1 15 6.1 1.7 3.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 GBG77991.1 - 0.024 15.0 0.4 0.024 15.0 0.4 2.9 3 2 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_TATA_bd PF12325.8 GBG77991.1 - 0.06 13.6 0.5 0.06 13.6 0.5 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RNR_Alpha PF17975.1 GBG77991.1 - 3.4 8.2 5.6 2.8 8.5 0.1 2.3 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain rve PF00665.26 GBG77993.1 - 5.8e-08 32.9 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG77994.1 - 0.0034 17.6 0.1 0.0034 17.6 0.1 3.4 4 0 0 4 4 4 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG77994.1 - 0.0071 16.1 0.8 0.027 14.2 0.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG77994.1 - 0.046 13.1 9.0 0.088 12.1 9.0 1.4 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 GBG77994.1 - 10 6.7 27.1 2.7 8.5 2.8 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region Retrotrans_gag PF03732.17 GBG77995.1 - 1.2 9.4 5.4 1.1 9.6 1.7 2.6 2 1 1 3 3 3 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG77996.1 - 8.8e-09 35.1 3.2 2.3e-08 33.7 3.2 1.8 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG77996.1 - 9.5e-07 28.5 0.4 0.091 12.3 0.0 3.4 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG77996.1 - 0.11 12.4 8.0 0.049 13.5 2.0 2.8 2 0 0 2 2 2 0 Zinc knuckle PPP4R2 PF09184.11 GBG77997.1 - 1.6 8.2 13.6 0.23 11.0 3.4 2.2 2 0 0 2 2 2 0 PPP4R2 CDC45 PF02724.14 GBG77997.1 - 3.7 5.7 12.7 0.22 9.7 6.4 1.8 2 0 0 2 2 2 0 CDC45-like protein CENP-B_dimeris PF09026.10 GBG77997.1 - 7.2 7.1 14.2 17 5.9 14.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RT_RNaseH PF17917.1 GBG77998.1 - 3e-47 159.3 3.3 7.2e-31 106.6 0.1 3.5 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG77998.1 - 1.5e-42 143.7 0.0 1.5e-29 101.9 0.0 3.5 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG77998.1 - 4.8e-19 68.8 0.1 1.3e-18 67.4 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) cNMP_binding PF00027.29 GBG77998.1 - 2.4e-09 37.1 0.0 6.2e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Retrotrans_gag PF03732.17 GBG77998.1 - 4.9e-06 26.7 0.9 0.048 13.9 0.0 4.8 3 0 0 3 3 3 1 Retrotransposon gag protein Csm1_N PF18504.1 GBG77999.1 - 0.033 14.5 0.1 0.033 14.5 0.1 2.6 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF2508 PF10704.9 GBG77999.1 - 0.66 10.2 8.6 12 6.2 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) DUF853 PF05872.12 GBG77999.1 - 1.1 7.8 10.0 0.21 10.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) PSK PF06404.12 GBG77999.1 - 1.7 9.7 8.9 0.26 12.3 3.6 2.3 2 1 0 2 2 2 0 Phytosulfokine precursor protein (PSK) RT_RNaseH PF17917.1 GBG78000.1 - 7.1e-44 148.4 2.0 1.2e-24 86.6 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78000.1 - 2e-36 124.0 0.1 1.2e-23 83.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78000.1 - 1.3e-19 70.0 0.0 3.1e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG78000.1 - 1.1e-16 61.1 0.0 3.1e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78000.1 - 9.2e-12 45.2 0.0 6.2e-06 26.4 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain Chromo PF00385.24 GBG78000.1 - 0.0003 20.7 0.0 0.4 10.6 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG78000.1 - 0.00067 19.8 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Tudor-knot PF11717.8 GBG78000.1 - 0.0013 18.6 0.0 0.0043 16.9 0.0 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-CCHC_3 PF13917.6 GBG78000.1 - 0.0016 18.4 0.8 0.0038 17.2 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle TOBE_2 PF08402.10 GBG78000.1 - 0.019 15.1 0.3 9.9 6.4 0.0 2.6 2 0 0 2 2 2 0 TOBE domain DUF1564 PF07600.11 GBG78000.1 - 0.062 13.0 3.9 0.08 12.6 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1564) zf-CCHC PF00098.23 GBG78000.1 - 0.38 10.9 3.6 0.91 9.7 3.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Filament PF00038.21 GBG78000.1 - 0.75 9.3 9.3 3.9 7.0 6.5 2.6 2 0 0 2 2 2 0 Intermediate filament protein RVT_1 PF00078.27 GBG78001.1 - 3.3e-32 111.8 0.1 6e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG78001.1 - 0.0038 17.9 2.3 0.006 17.3 0.3 2.4 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase DNA_pol_lambd_f PF10391.9 GBG78001.1 - 0.079 12.8 0.2 0.38 10.6 0.1 2.1 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Collagen PF01391.18 GBG78003.1 - 0.0085 15.8 6.6 0.017 14.9 6.6 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) RT_RNaseH_2 PF17919.1 GBG78004.1 - 5.2e-21 74.6 0.0 9.5e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78004.1 - 6.5e-21 74.6 0.0 1.3e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78004.1 - 1.5e-15 57.4 0.0 3.5e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78004.1 - 4e-12 46.0 0.1 1.2e-11 44.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG78004.1 - 0.0047 16.7 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG78005.1 - 4.4e-14 52.3 0.0 8.8e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78005.1 - 1.1e-13 51.4 0.0 2.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG78005.1 - 2.2e-10 40.4 0.1 3.3e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78005.1 - 1.2e-05 25.3 0.3 3.8e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG78005.1 - 2.5e-05 24.5 0.0 6.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG78005.1 - 0.0029 17.8 0.0 0.0059 16.8 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger PLATZ PF04640.14 GBG78005.1 - 0.12 13.0 0.0 0.41 11.3 0.0 1.9 1 0 0 1 1 1 0 PLATZ transcription factor MLVIN_C PF18697.1 GBG78005.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain CDC45 PF02724.14 GBG78005.1 - 3.6 5.8 19.8 5.4 5.2 19.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG78005.1 - 4.6 6.6 26.1 7.4 5.9 26.1 1.2 1 0 0 1 1 1 0 SDA1 tRNA-synt_1c PF00749.21 GBG78006.1 - 2e-103 345.6 0.0 2.9e-103 345.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Exonuc_VII_S PF02609.16 GBG78006.1 - 0.13 12.3 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Exonuclease VII small subunit RVP_2 PF08284.11 GBG78007.1 - 7e-08 32.3 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF2913 PF11140.8 GBG78007.1 - 0.00082 19.2 1.9 0.0017 18.2 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2913) Retrotrans_gag PF03732.17 GBG78007.1 - 0.0041 17.4 0.3 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Snapin_Pallidin PF14712.6 GBG78007.1 - 0.012 16.0 3.1 0.064 13.7 0.0 2.6 2 0 0 2 2 2 0 Snapin/Pallidin gag-asp_proteas PF13975.6 GBG78007.1 - 0.015 15.8 0.0 0.043 14.4 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78007.1 - 0.018 15.6 0.0 0.046 14.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease HAUS4 PF14735.6 GBG78007.1 - 0.21 11.3 7.8 0.37 10.5 7.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF349 PF03993.12 GBG78007.1 - 0.21 11.9 5.7 0.35 11.2 3.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Dimer_Tnp_hAT PF05699.14 GBG78008.1 - 1.8e-07 30.8 0.1 5e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG78010.1 - 1.4e-32 111.7 0.3 3.2e-32 110.5 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78010.1 - 4.2e-27 94.5 0.5 9.4e-27 93.4 0.5 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78010.1 - 2.4e-21 76.2 0.8 1.3e-13 51.2 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain PUF PF00806.19 GBG78010.1 - 0.02 14.6 0.2 6.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Reprolysin_4 PF13583.6 GBG78010.1 - 0.039 13.6 0.1 0.15 11.7 0.1 1.8 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF3837 PF12939.7 GBG78010.1 - 0.079 13.4 0.1 20 5.6 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) rve_3 PF13683.6 GBG78010.1 - 0.11 12.4 0.4 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH PF17917.1 GBG78011.1 - 8e-30 103.2 1.5 2.1e-29 101.9 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78011.1 - 8e-30 102.8 0.0 4.7e-29 100.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78011.1 - 3.1e-19 68.8 0.5 6.6e-19 67.8 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78011.1 - 6.9e-16 58.5 0.0 2.7e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG78011.1 - 3.5e-12 46.8 0.0 2.5e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG78011.1 - 6.5e-12 45.8 0.0 5e-05 23.8 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG78011.1 - 7.2e-10 38.8 0.0 4.5e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 GBG78011.1 - 1.1e-06 28.5 0.0 0.031 14.0 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease zf-H2C2 PF09337.10 GBG78011.1 - 0.00088 19.4 0.1 0.0023 18.1 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG78011.1 - 0.0031 17.8 2.3 12 6.3 0.0 4.7 6 0 0 6 6 3 2 Retrotransposon gag protein RVP PF00077.20 GBG78011.1 - 0.027 14.8 0.0 15 5.9 0.0 2.7 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG78012.1 - 1.6e-31 109.6 0.1 2.4e-31 109.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78012.1 - 7e-18 64.5 0.0 1.6e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78012.1 - 2.4e-16 59.6 0.4 5.1e-16 58.5 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG78012.1 - 9e-10 38.8 0.1 4.2e-06 27.0 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78012.1 - 0.0025 18.0 0.1 1.9 8.7 0.0 2.8 1 1 1 2 2 2 2 Integrase core domain Chromo PF00385.24 GBG78012.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RR_TM4-6 PF06459.12 GBG78013.1 - 0.03 14.2 9.8 0.039 13.8 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YL1 PF05764.13 GBG78013.1 - 0.2 11.8 22.8 0.33 11.0 22.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG78013.1 - 0.38 10.0 22.6 0.49 9.7 22.6 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG78013.1 - 0.66 8.7 3.6 0.76 8.5 3.6 1.2 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 GBG78013.1 - 1.8 7.5 5.8 2.2 7.2 5.8 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Merozoite_SPAM PF07133.11 GBG78013.1 - 2 8.4 30.9 0.086 12.8 15.3 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) AAA_11 PF13086.6 GBG78013.1 - 6 6.6 6.5 6.5 6.4 6.5 1.2 1 1 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 GBG78015.1 - 0.00019 21.4 2.5 0.00032 20.6 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle TFIIA PF03153.13 GBG78015.1 - 0.024 14.6 6.9 0.034 14.2 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCHC_2 PF13696.6 GBG78015.1 - 0.18 11.6 3.1 0.28 11.1 3.1 1.2 1 0 0 1 1 1 0 Zinc knuckle MIF4G_like_2 PF09090.11 GBG78015.1 - 8.1 5.8 9.4 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 MIF4G like Pkinase PF00069.25 GBG78017.1 - 1.5e-51 175.3 0.0 5.2e-39 134.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG78017.1 - 1.4e-27 96.7 0.0 8.9e-24 84.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG78017.1 - 1.6e-07 30.5 0.0 2.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GBG78017.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GBG78017.1 - 0.0035 17.3 0.2 0.0072 16.3 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GBG78017.1 - 0.03 13.7 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GBG78017.1 - 0.24 10.3 0.1 0.35 9.8 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain TAD2 PF18521.1 GBG78018.1 - 0.016 15.2 0.6 0.65 10.1 0.0 2.9 3 0 0 3 3 3 0 Transactivation domain 2 Mito_fiss_reg PF05308.11 GBG78018.1 - 0.03 14.4 1.1 0.1 12.7 0.4 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF5102 PF17104.5 GBG78018.1 - 0.052 13.6 0.6 0.077 13.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) DUF2312 PF10073.9 GBG78018.1 - 0.11 12.2 1.7 0.39 10.4 0.1 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Macoilin PF09726.9 GBG78018.1 - 0.13 10.7 4.5 0.23 10.0 4.5 1.3 1 0 0 1 1 1 0 Macoilin family gag-asp_proteas PF13975.6 GBG78019.1 - 9.6e-05 22.9 0.1 0.00031 21.3 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78019.1 - 0.0012 19.4 0.0 0.0033 18.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease ZapB PF06005.12 GBG78019.1 - 0.0033 17.8 4.1 0.0033 17.8 4.1 3.9 5 1 0 5 5 5 1 Cell division protein ZapB Prominin PF05478.11 GBG78019.1 - 0.045 11.7 0.8 0.071 11.1 0.8 1.2 1 0 0 1 1 1 0 Prominin Snapin_Pallidin PF14712.6 GBG78019.1 - 0.41 11.1 5.2 3.1 8.3 1.3 3.2 3 0 0 3 3 3 0 Snapin/Pallidin COMP PF11598.8 GBG78019.1 - 2 9.0 5.6 5.1 7.7 5.6 1.7 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein RT_RNaseH_2 PF17919.1 GBG78020.1 - 0.00021 21.3 0.0 0.00049 20.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78020.1 - 0.0061 16.8 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3450 PF11932.8 GBG78020.1 - 2.3 7.5 6.3 0.41 9.9 1.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF659 PF04937.15 GBG78021.1 - 0.054 13.3 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) UEV PF05743.13 GBG78022.1 - 3.9e-28 97.7 0.0 6.5e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 GBG78022.1 - 6.7e-19 67.6 0.3 1.2e-18 66.8 0.3 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 GBG78022.1 - 0.051 13.2 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme KxDL PF10241.9 GBG78022.1 - 0.056 13.7 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein RT_RNaseH_2 PF17919.1 GBG78023.1 - 4.4e-41 139.0 0.0 1.7e-21 76.1 0.0 3.2 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78023.1 - 1.9e-32 112.6 0.1 7.8e-28 97.5 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78023.1 - 7e-31 106.6 0.0 6.3e-21 74.6 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG78023.1 - 2.4e-16 60.1 0.0 4.7e-07 30.4 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG78023.1 - 3.1e-15 56.1 0.0 1.1e-06 28.4 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG78023.1 - 4.8e-13 49.5 0.0 6.2e-06 26.7 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG78023.1 - 3.6e-08 33.2 0.0 0.0018 18.1 0.0 2.8 3 0 0 3 3 3 2 Aspartyl protease Retrotrans_gag PF03732.17 GBG78023.1 - 5.1e-06 26.7 15.7 0.024 14.9 0.2 6.2 6 0 0 6 6 6 3 Retrotransposon gag protein Chromo PF00385.24 GBG78023.1 - 1.9e-05 24.4 0.3 0.012 15.4 0.3 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG78023.1 - 0.0065 16.6 0.0 0.039 14.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVP PF00077.20 GBG78023.1 - 0.14 12.5 0.0 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG78024.1 - 2.1e-55 184.9 0.0 1.3e-29 102.1 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78024.1 - 1.5e-48 163.4 0.1 4.2e-26 91.3 0.2 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78024.1 - 1.7e-27 96.4 0.2 3.3e-27 95.5 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78024.1 - 1.1e-07 31.8 0.1 2.4e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78024.1 - 1.9e-06 28.1 0.4 0.00015 21.9 0.1 2.7 2 0 0 2 2 2 1 Integrase core domain Scaffolding_pro PF11418.8 GBG78024.1 - 0.1 13.2 2.8 4.2 8.0 0.1 2.9 2 0 0 2 2 2 0 Phi29 scaffolding protein DUF4407 PF14362.6 GBG78024.1 - 4.8 6.4 16.8 4.3 6.6 4.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) YmaF PF12788.7 GBG78025.1 - 0.12 12.9 10.1 2.9 8.5 0.4 2.9 1 1 2 3 3 3 0 YmaF family zf-B_box PF00643.24 GBG78026.1 - 7.7e-09 35.6 8.9 8.2e-08 32.3 1.3 2.2 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.5 GBG78026.1 - 0.01 16.1 0.9 0.01 16.1 0.9 2.2 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain C1_1 PF00130.22 GBG78026.1 - 0.057 13.3 0.9 0.057 13.3 0.9 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 GBG78026.1 - 0.28 11.5 4.6 0.099 13.0 1.6 1.8 1 1 1 2 2 2 0 C1 domain AAA_33 PF13671.6 GBG78027.1 - 9.5e-07 29.1 0.0 3.4e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GBG78027.1 - 1.1e-05 26.0 0.0 0.00018 22.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GBG78027.1 - 0.00036 20.8 0.1 0.0015 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GBG78027.1 - 0.0008 18.7 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.15 GBG78027.1 - 0.0025 17.8 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain PAC4 PF16093.5 GBG78027.1 - 0.0029 17.8 0.3 0.0076 16.4 0.3 1.7 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 RsgA_GTPase PF03193.16 GBG78027.1 - 0.0035 17.3 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 GBG78027.1 - 0.0042 17.5 0.0 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GBG78027.1 - 0.0057 17.0 0.0 0.053 13.9 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.6 GBG78027.1 - 0.013 15.9 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GBG78027.1 - 0.015 15.9 0.1 0.031 14.8 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 GBG78027.1 - 0.025 15.0 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 GBG78027.1 - 0.026 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GBG78027.1 - 0.042 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 GBG78027.1 - 0.055 13.5 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PRK PF00485.18 GBG78027.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 GBG78027.1 - 0.07 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 GBG78027.1 - 0.08 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 GBG78027.1 - 0.092 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Cytidylate_kin PF02224.18 GBG78027.1 - 0.17 11.6 0.4 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase She2p PF11435.8 GBG78027.1 - 0.17 11.5 0.2 0.27 10.9 0.2 1.2 1 0 0 1 1 1 0 RNA binding protein She2p Ribosomal_L37ae PF01780.19 GBG78029.1 - 2.9e-39 133.0 5.3 3.2e-39 132.9 5.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 GBG78029.1 - 0.0039 17.3 0.2 0.0053 16.9 0.2 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-FPG_IleRS PF06827.14 GBG78029.1 - 0.054 13.4 3.4 0.062 13.2 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 GBG78029.1 - 0.11 12.6 1.2 0.23 11.6 1.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 GBG78029.1 - 0.29 11.7 3.1 8.4 7.0 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain CarbpepA_inh PF02977.15 GBG78029.1 - 0.6 9.9 3.6 3.2 7.6 0.2 2.2 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor MA3 PF02847.17 GBG78031.1 - 2.6e-27 95.1 0.7 4.4e-27 94.3 0.7 1.4 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 GBG78031.1 - 1.4e-10 41.2 0.0 2.6e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain Ish1 PF10281.9 GBG78032.1 - 0.092 13.1 0.8 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein OB_Dis3 PF17849.1 GBG78034.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) DUF713 PF05218.14 GBG78034.1 - 0.2 11.4 0.7 0.41 10.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF713) ZapB PF06005.12 GBG78034.1 - 0.99 9.9 14.7 0.85 10.1 4.0 3.1 3 0 0 3 3 3 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 GBG78034.1 - 3.4 7.9 12.0 0.034 14.4 2.2 2.3 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Autophagy_N PF03986.13 GBG78035.1 - 0.077 12.9 0.1 0.077 12.9 0.1 3.1 2 1 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain HALZ PF02183.18 GBG78036.1 - 0.041 14.1 0.2 0.14 12.4 0.2 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper CCD48 PF15799.5 GBG78036.1 - 0.042 12.2 0.6 0.067 11.5 0.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 bZIP_2 PF07716.15 GBG78036.1 - 0.058 13.5 0.7 0.19 11.8 0.7 1.9 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 GBG78036.1 - 0.12 12.2 0.6 0.39 10.5 0.6 1.9 1 0 0 1 1 1 0 Septum formation initiator ABC_tran_CTD PF16326.5 GBG78036.1 - 3.7 7.9 5.5 1.1 9.5 1.2 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain RT_RNaseH_2 PF17919.1 GBG78037.1 - 1.6e-22 79.4 0.0 4.4e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78037.1 - 5.4e-21 74.8 0.0 4.4e-20 71.9 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78037.1 - 1e-15 58.0 0.0 3.1e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78037.1 - 1.1e-05 25.5 0.0 3.8e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG78037.1 - 0.0021 17.8 0.0 0.0065 16.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG78037.1 - 0.013 15.7 0.1 0.045 14.0 0.1 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG78037.1 - 0.16 11.8 0.9 0.33 10.8 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG78038.1 - 0.029 14.6 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein UFD1 PF03152.14 GBG78038.1 - 0.076 12.5 0.2 0.17 11.3 0.2 1.5 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 RT_RNaseH PF17917.1 GBG78040.1 - 8.4e-25 87.1 0.0 2.2e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78040.1 - 1.7e-23 82.5 0.0 5e-23 81.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78040.1 - 2.2e-22 79.7 0.8 5.2e-22 78.5 0.2 2.0 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78040.1 - 6.3e-09 36.0 0.2 3.4e-08 33.7 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain RVP_2 PF08284.11 GBG78040.1 - 0.0033 17.2 0.3 0.0064 16.3 0.3 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Csm1_N PF18504.1 GBG78040.1 - 0.069 13.5 0.3 0.069 13.5 0.3 2.4 3 0 0 3 3 3 0 Csm1 N-terminal domain RVT_1 PF00078.27 GBG78041.1 - 7e-37 127.1 0.0 1.3e-36 126.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78041.1 - 7.2e-19 68.0 0.8 2e-18 66.6 0.8 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78041.1 - 1.8e-09 37.5 0.1 5.6e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG78041.1 - 1.3 8.5 6.7 0.5 9.9 0.1 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase MT PF12777.7 GBG78042.1 - 0.00031 19.9 2.7 0.00045 19.3 2.7 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor PEX-2N PF09263.10 GBG78043.1 - 0.015 15.6 0.4 0.036 14.4 0.4 1.7 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal DUF4939 PF16297.5 GBG78043.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) eIF3g PF12353.8 GBG78043.1 - 0.12 12.8 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Exonuc_VII_L PF02601.15 GBG78043.1 - 0.24 10.9 4.5 0.46 10.0 4.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit RT_RNaseH_2 PF17919.1 GBG78044.1 - 1e-29 102.5 0.0 2.2e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78044.1 - 5.3e-25 87.7 0.0 1e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78044.1 - 2e-24 86.3 0.1 4.8e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78044.1 - 2.2e-15 56.9 0.0 4.7e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78044.1 - 5.7e-14 52.0 0.1 1.6e-13 50.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78044.1 - 0.013 15.7 0.0 0.042 14.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger SIL1 PF16782.5 GBG78044.1 - 0.22 10.7 1.1 0.43 9.8 1.1 1.4 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 Phage_GPO PF05929.11 GBG78044.1 - 0.34 10.5 2.3 25 4.4 0.0 2.7 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF659 PF04937.15 GBG78045.1 - 1.1e-23 83.8 0.1 1.9e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78045.1 - 7.2e-05 22.5 0.1 0.00021 21.0 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG78046.1 - 3.1e-31 108.6 0.2 5.9e-31 107.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78046.1 - 7.4e-21 74.1 0.0 2.3e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78046.1 - 3.5e-09 36.9 0.0 8.6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop53 PF07767.11 GBG78046.1 - 0.1 11.9 10.3 0.24 10.8 10.3 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) USP8_interact PF08941.10 GBG78047.1 - 0.099 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 USP8 interacting DUF659 PF04937.15 GBG78048.1 - 1.7e-13 50.7 0.1 7.3e-12 45.4 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) Cwf_Cwc_15 PF04889.12 GBG78048.1 - 0.78 9.4 14.3 2.1 8.0 14.3 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Asp_protease PF09668.10 GBG78051.1 - 0.00051 19.8 0.1 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78051.1 - 0.0022 18.5 0.2 0.01 16.4 0.1 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78051.1 - 0.047 14.3 0.1 0.16 12.6 0.1 2.0 1 0 0 1 1 1 0 Aspartyl protease DUF1805 PF08827.11 GBG78051.1 - 0.12 12.7 0.7 7.7 6.9 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) DDHD PF02862.17 GBG78051.1 - 2.4 8.3 10.7 3.3 7.8 9.7 2.0 1 1 0 1 1 1 0 DDHD domain Dynamin_N PF00350.23 GBG78051.1 - 9.5 6.2 8.3 0.43 10.6 1.3 2.2 2 1 0 2 2 2 0 Dynamin family N6_N4_Mtase PF01555.18 GBG78053.1 - 5.4e-08 32.8 0.0 1e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 DNA methylase Paf1 PF03985.13 GBG78054.1 - 2.9 6.8 17.6 3.3 6.6 17.6 1.0 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 GBG78054.1 - 3.4 5.9 11.0 3.6 5.7 11.0 1.0 1 0 0 1 1 1 0 CDC45-like protein CENP-T_N PF16171.5 GBG78054.1 - 3.4 6.5 6.1 3.9 6.3 6.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus DNA_pol_phi PF04931.13 GBG78055.1 - 3.8 5.5 28.7 5.9 4.9 28.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi RVT_1 PF00078.27 GBG78056.1 - 2e-35 122.4 0.1 3.7e-35 121.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78056.1 - 1.4e-16 60.3 0.0 4.6e-16 58.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG78056.1 - 9.6e-08 31.9 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG78056.1 - 4.2e-07 30.2 0.0 1.2e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG78056.1 - 3.6e-05 24.3 0.0 7.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78056.1 - 0.00014 22.4 0.1 0.0005 20.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG78056.1 - 0.063 13.1 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease DUF1758 PF05585.12 GBG78056.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG78057.1 - 4.6e-07 29.7 0.0 9.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78057.1 - 8.4e-06 26.3 0.0 3.1e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78057.1 - 0.0013 19.3 0.1 0.0091 16.5 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG78057.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG78058.1 - 1.2e-30 106.7 0.0 2.1e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78058.1 - 1.2e-27 95.8 0.0 3.4e-27 94.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78058.1 - 1.1e-24 86.7 0.4 4.5e-24 84.8 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase CCD48 PF15799.5 GBG78058.1 - 0.0011 17.4 3.2 0.0018 16.7 3.2 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 CCDC85 PF10226.9 GBG78058.1 - 0.026 14.2 1.3 0.059 13.1 0.2 2.1 2 0 0 2 2 2 0 CCDC85 family HALZ PF02183.18 GBG78058.1 - 0.042 14.1 2.0 0.11 12.7 2.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF848 PF05852.11 GBG78058.1 - 0.074 13.2 1.6 0.21 11.7 1.6 1.7 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) GvpL_GvpF PF06386.11 GBG78058.1 - 0.075 13.0 6.8 0.21 11.5 6.8 1.7 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF2385 PF09539.10 GBG78058.1 - 0.18 12.3 0.4 2.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) bZIP_1 PF00170.21 GBG78058.1 - 2.3 8.4 6.1 0.24 11.5 1.2 1.9 2 0 0 2 2 2 0 bZIP transcription factor AAA_9 PF12781.7 GBG78059.1 - 2.8e-18 65.9 0.9 4.4e-18 65.2 0.9 1.2 1 0 0 1 1 1 1 ATP-binding dynein motor region SIMPL PF04402.14 GBG78059.1 - 0.071 13.6 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) RVT_1 PF00078.27 GBG78060.1 - 7e-32 110.7 0.1 1.3e-31 109.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78060.1 - 4.2e-19 68.8 0.0 9.6e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78060.1 - 2e-15 56.7 0.0 5.6e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG78060.1 - 1.1e-09 38.3 0.0 1.2e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78060.1 - 4.8e-08 33.2 0.1 2.5e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG78060.1 - 4.5e-06 26.8 0.0 1.2e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG78061.1 - 2.6e-30 104.4 0.0 8.7e-15 54.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78061.1 - 1.2e-29 102.6 0.0 2.7e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78061.1 - 2.7e-27 95.8 0.0 4.8e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1727 PF08353.10 GBG78063.1 - 0.14 12.1 0.2 0.27 11.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) DUF659 PF04937.15 GBG78066.1 - 2.6e-19 69.6 0.0 4.3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) HTH_32 PF13565.6 GBG78066.1 - 0.5 11.0 4.7 0.26 11.9 0.3 2.7 2 0 0 2 2 2 0 Homeodomain-like domain Dynein_C PF18199.1 GBG78067.1 - 3.3e-107 358.3 0.0 4.9e-107 357.7 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 GBG78067.1 - 1.6e-59 200.4 0.0 2.7e-59 199.6 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GBG78067.1 - 3.7e-45 152.9 0.0 8.9e-45 151.6 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 GBG78067.1 - 0.0091 15.1 0.1 0.024 13.8 0.1 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region DUF659 PF04937.15 GBG78068.1 - 2.1e-10 40.7 0.0 4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78068.1 - 0.002 17.9 0.0 0.0065 16.2 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG78069.1 - 3.4e-58 193.9 0.1 1.4e-29 102.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78069.1 - 7.1e-52 174.1 0.3 2.7e-25 88.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78069.1 - 7.9e-22 77.9 0.1 1.6e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78069.1 - 1.9e-15 56.7 0.2 4.8e-15 55.4 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain CotJB PF12652.7 GBG78069.1 - 0.0043 17.2 0.5 6.2 7.1 0.0 4.1 3 0 0 3 3 3 1 CotJB protein rve PF00665.26 GBG78069.1 - 0.081 13.1 0.1 1.6 9.0 0.0 2.7 2 1 0 2 2 2 0 Integrase core domain DUF3134 PF11332.8 GBG78070.1 - 6.3 7.2 7.3 1.1 9.6 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) DUF4614 PF15391.6 GBG78072.1 - 6.6 6.7 12.0 7.5 6.5 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) ketoacyl-synt PF00109.26 GBG78074.1 - 1.2e-55 188.9 0.4 1.3e-54 185.4 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GBG78074.1 - 4.1e-32 110.7 1.1 1e-31 109.4 1.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GBG78074.1 - 0.00056 19.4 2.0 0.0019 17.6 0.3 2.3 2 1 0 3 3 3 1 Thiolase, N-terminal domain RVT_1 PF00078.27 GBG78075.1 - 6.9e-21 74.8 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78075.1 - 1.6e-14 53.7 0.0 5.7e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78075.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase tRNA_deacylase PF04414.12 GBG78075.1 - 0.044 13.3 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 D-aminoacyl-tRNA deacylase Retrotrans_gag PF03732.17 GBG78075.1 - 0.13 12.6 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG78076.1 - 2.5e-24 85.2 0.0 6.4e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78076.1 - 4.4e-23 81.6 0.0 1.2e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78076.1 - 2.4e-18 66.0 0.3 5.7e-18 64.8 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG78076.1 - 8.4e-11 41.8 1.8 1.7e-10 40.8 0.0 2.3 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG78076.1 - 0.0016 18.7 3.9 0.0058 16.9 0.2 3.4 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG78076.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Baculo_PEP_C PF04513.12 GBG78076.1 - 1.9 8.5 5.4 2 8.4 2.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PspB PF06667.12 GBG78076.1 - 6.5 6.9 7.7 22 5.2 0.1 3.1 2 0 0 2 2 2 0 Phage shock protein B RVT_1 PF00078.27 GBG78077.1 - 2.9e-30 105.4 0.0 3.8e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78077.1 - 6.1e-15 55.1 0.0 1.9e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78077.1 - 2.3e-07 31.0 0.0 4.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG78077.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH PF17917.1 GBG78078.1 - 0.00016 21.9 0.0 0.0021 18.3 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG78078.1 - 0.016 15.8 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG78078.1 - 0.023 15.0 0.9 0.11 12.8 0.1 2.5 2 1 1 3 3 3 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG78078.1 - 0.026 14.6 0.1 0.055 13.5 0.1 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG78078.1 - 0.11 12.8 0.2 0.29 11.4 0.2 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Histone PF00125.24 GBG78079.1 - 6.7e-08 33.0 0.1 1.3e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RRM_1 PF00076.22 GBG78081.1 - 1.2e-47 159.6 0.0 5.6e-15 54.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG78081.1 - 1.6e-06 28.1 0.1 0.064 13.4 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 GBG78081.1 - 2.6e-05 24.2 0.0 0.00072 19.6 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 GBG78081.1 - 3e-05 23.6 0.0 0.021 14.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG78081.1 - 0.0017 18.3 0.1 0.017 15.1 0.0 2.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 GBG78081.1 - 0.14 11.9 0.5 24 4.7 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain T4SS PF07996.11 GBG78085.1 - 1.6 9.1 9.0 0.53 10.6 5.8 1.7 2 0 0 2 2 2 0 Type IV secretion system proteins RT_RNaseH_2 PF17919.1 GBG78088.1 - 3.7e-27 94.3 0.0 6.4e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78088.1 - 2.8e-26 91.9 0.0 4.8e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78088.1 - 1.2e-12 47.8 0.0 1.8e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG78088.1 - 0.099 10.8 31.3 0.14 10.4 31.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG78088.1 - 0.23 10.8 32.5 0.33 10.3 32.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG78088.1 - 0.32 9.2 23.7 0.49 8.6 23.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2249 PF10006.9 GBG78088.1 - 0.43 10.5 3.5 1.7 8.5 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2249) TFIIF_alpha PF05793.12 GBG78088.1 - 2.3 6.7 32.9 3.6 6.1 32.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 GBG78088.1 - 2.4 7.4 30.8 3.6 6.8 30.8 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 GBG78088.1 - 3.2 6.1 30.7 5.3 5.4 30.7 1.2 1 0 0 1 1 1 0 Mpp10 protein Topo_Zn_Ribbon PF08272.11 GBG78090.1 - 0.016 14.9 0.3 0.029 14.0 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RRM_1 PF00076.22 GBG78091.1 - 8.2e-09 35.2 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG78091.1 - 0.037 14.0 0.1 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CytochromB561_N PF09786.9 GBG78091.1 - 3.5 6.5 4.9 5.9 5.8 4.9 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal RRM_1 PF00076.22 GBG78092.1 - 8.1e-09 35.2 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG78092.1 - 0.036 14.1 0.1 0.069 13.2 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CytochromB561_N PF09786.9 GBG78092.1 - 3 6.7 6.6 4.9 6.0 6.6 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ribosomal_S4 PF00163.19 GBG78094.1 - 3.5e-10 40.7 1.1 4.2e-10 40.4 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Occludin_ELL PF07303.13 GBG78094.1 - 0.043 14.5 0.0 0.056 14.2 0.0 1.3 1 0 0 1 1 1 0 Occludin homology domain DNA_pol3_beta_2 PF02767.16 GBG78094.1 - 0.071 13.3 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III beta subunit, central domain Ribosomal_S6e PF01092.19 GBG78096.1 - 3.2e-55 185.5 0.0 6.7e-55 184.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e RT_RNaseH PF17917.1 GBG78097.1 - 7.9e-23 80.8 0.0 2.1e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78097.1 - 1.7e-21 76.1 0.0 3.5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78097.1 - 1.8e-17 63.1 2.2 4.8e-17 61.8 2.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78097.1 - 7.8e-16 58.3 0.0 1.8e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG78097.1 - 5.4e-09 35.9 0.0 9.5e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG78097.1 - 0.0053 17.0 0.4 0.017 15.3 0.4 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Rieske PF00355.26 GBG78098.1 - 8.7e-17 60.9 0.0 1.8e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG78098.1 - 9.9e-14 51.3 0.0 3e-13 49.7 0.0 1.8 1 1 1 2 2 2 1 Pheophorbide a oxygenase RT_RNaseH PF17917.1 GBG78099.1 - 1.9e-29 102.0 0.0 6.6e-29 100.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78099.1 - 2.6e-29 101.2 0.0 7.4e-29 99.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rieske PF00355.26 GBG78099.1 - 2e-16 59.7 0.0 4.7e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG78099.1 - 1.6e-13 50.6 0.1 3.8e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 Pheophorbide a oxygenase RVT_1 PF00078.27 GBG78099.1 - 2.1e-12 47.1 0.1 3.9e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2866 PF11065.8 GBG78099.1 - 0.11 12.6 0.1 1.6 8.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) Glyoxalase_6 PF18029.1 GBG78099.1 - 0.71 10.7 3.6 0.62 10.9 0.5 2.6 2 0 0 2 2 2 0 Glyoxalase-like domain NdhM PF10664.9 GBG78100.1 - 1.8e-42 143.9 0.1 2.5e-42 143.5 0.1 1.2 1 0 0 1 1 1 1 Cyanobacterial and plastid NDH-1 subunit M DNA_pol_E_B PF04042.16 GBG78101.1 - 1.3e-34 119.4 0.0 1.9e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 GBG78101.1 - 6.5e-05 23.0 2.0 0.00015 21.9 0.0 2.5 3 0 0 3 3 3 1 DNA polymerase alpha subunit B N-terminal DUF3043 PF11241.8 GBG78102.1 - 0.15 12.1 1.7 0.23 11.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DNA_pol_phi PF04931.13 GBG78103.1 - 0.67 8.0 10.4 0.77 7.8 10.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GBG78103.1 - 5.5 5.4 6.4 5.9 5.3 6.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RVT_1 PF00078.27 GBG78104.1 - 1e-28 100.4 0.1 2.1e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78104.1 - 1.5e-15 57.1 0.0 3.6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78104.1 - 1.7e-14 54.0 0.0 4e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain PAC2 PF09754.9 GBG78106.1 - 2.7e-24 86.4 0.0 3.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 PAC2 family DUF4366 PF14283.6 GBG78107.1 - 0.085 12.9 0.2 14 5.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) BES1_N PF05687.13 GBG78107.1 - 0.72 10.2 9.1 0.7 10.3 2.1 2.2 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal Ribosomal_60s PF00428.19 GBG78107.1 - 1.4 9.6 24.6 0.39 11.3 4.4 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein H_PPase PF03030.16 GBG78108.1 - 2.9e-220 733.3 35.4 3.6e-220 733.0 35.4 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Sec23_trunk PF04811.15 GBG78109.1 - 4.4e-71 239.3 0.0 5.9e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GBG78109.1 - 1.6e-21 76.8 0.2 5.4e-21 75.2 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 GBG78109.1 - 1.3e-20 73.2 0.3 2e-20 72.5 0.3 1.3 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GBG78109.1 - 1.4e-16 60.2 2.2 1.4e-16 60.2 2.2 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GBG78109.1 - 1.6e-11 43.9 0.0 4.5e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat MRNIP PF15749.5 GBG78109.1 - 0.13 13.0 0.1 0.21 12.3 0.1 1.3 1 0 0 1 1 1 0 MRN-interacting protein Sen15 PF09631.10 GBG78109.1 - 0.18 12.1 0.0 0.54 10.6 0.0 1.7 1 0 0 1 1 1 0 Sen15 protein EPSP_synthase PF00275.20 GBG78110.1 - 2.5e-138 461.3 0.0 1.4e-137 458.8 0.0 1.8 1 1 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) ABC_tran PF00005.27 GBG78111.1 - 3.6e-14 53.4 0.0 5.7e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GBG78111.1 - 9.2e-07 28.5 1.2 0.016 14.7 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GBG78111.1 - 5.5e-06 26.4 0.0 0.052 13.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GBG78111.1 - 0.0042 16.8 0.2 0.0086 15.8 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 GBG78111.1 - 0.027 13.1 0.0 0.038 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG78111.1 - 0.039 14.5 0.0 0.085 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GBG78111.1 - 0.042 13.7 0.2 0.065 13.1 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 GBG78111.1 - 0.055 14.0 0.2 0.11 13.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GBG78111.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4611 PF15387.6 GBG78112.1 - 0.86 9.9 11.3 0.35 11.1 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) WRNPLPNID PF15017.6 GBG78112.1 - 5.9 7.9 13.2 18 6.3 1.1 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Autophagy_N PF03986.13 GBG78113.1 - 0.0041 17.1 0.4 0.0065 16.4 0.4 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Rho_N PF07498.12 GBG78113.1 - 0.011 15.7 0.3 0.018 15.0 0.3 1.3 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Cyclin_N PF00134.23 GBG78114.1 - 4.5e-44 149.2 1.0 4.5e-44 149.2 1.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GBG78114.1 - 1.1e-35 122.3 1.2 2.5e-35 121.2 1.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Carb_kinase PF01256.17 GBG78116.1 - 5.1e-48 163.7 0.0 6.8e-47 160.0 0.0 2.1 1 1 0 1 1 1 1 Carbohydrate kinase DUF5566 PF17721.1 GBG78116.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5566) Hydantoinase_A PF01968.18 GBG78117.1 - 1.4e-101 339.7 0.4 2.6e-101 338.7 0.4 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GBG78117.1 - 1.7e-61 207.1 0.2 2.7e-59 199.9 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region RVT_1 PF00078.27 GBG78117.1 - 4.9e-28 98.1 0.0 9.5e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78117.1 - 3e-24 84.9 0.2 5e-22 77.8 0.2 2.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78117.1 - 2e-18 66.6 1.0 5.2e-16 58.8 1.0 2.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78117.1 - 6.3e-16 58.2 1.0 1.5e-15 57.0 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG78117.1 - 7e-13 48.8 0.0 1.8e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Hydantoinase_B PF02538.14 GBG78117.1 - 2e-09 36.4 0.0 3.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase RVP_2 PF08284.11 GBG78117.1 - 3.1e-05 23.8 0.0 6.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78117.1 - 0.0042 17.7 0.0 0.049 14.3 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78117.1 - 0.024 15.2 0.0 0.093 13.3 0.0 2.0 2 0 0 2 2 1 0 gag-polyprotein putative aspartyl protease Phage_GPO PF05929.11 GBG78117.1 - 0.077 12.6 1.4 11 5.5 0.4 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase CENP-Q PF13094.6 GBG78117.1 - 0.1 12.8 4.7 0.24 11.6 4.7 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit YscO-like PF16789.5 GBG78117.1 - 1.5 8.8 7.0 0.72 9.9 2.0 2.6 3 0 0 3 3 3 0 YscO-like protein Integrase_H2C2 PF17921.1 GBG78118.1 - 6.6e-16 58.2 0.2 1.3e-15 57.2 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG78118.1 - 1.9e-15 57.0 0.6 3.3e-15 56.3 0.6 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78118.1 - 1.4e-11 44.6 0.1 4.4e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG78118.1 - 4.5e-08 33.1 0.2 8.7e-08 32.1 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG78118.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG78119.1 - 8e-26 90.0 0.1 1.6e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78119.1 - 1.5e-12 47.7 0.0 3.3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78119.1 - 1.9e-12 47.2 0.4 3.8e-12 46.2 0.4 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG78121.1 - 0.011 15.3 0.1 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Hydantoinase_B PF02538.14 GBG78122.1 - 8.1e-118 394.0 0.1 1.2e-117 393.5 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase tRNA-synt_1b PF00579.25 GBG78124.1 - 2.5e-35 122.2 0.0 4.2e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Lipocalin_5 PF13924.6 GBG78125.1 - 0.077 12.8 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Lipocalin-like domain Plasmid_RAQPRD PF09686.10 GBG78125.1 - 0.27 11.4 8.9 2.2 8.5 0.7 3.0 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) LYRIC PF15686.5 GBG78125.1 - 2 7.9 19.6 4.9 6.6 19.6 1.6 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family YebG PF07130.12 GBG78125.1 - 2.5 8.0 6.2 0.86 9.5 0.6 2.9 3 0 0 3 3 3 0 YebG protein Baculo_PEP_C PF04513.12 GBG78125.1 - 4.2 7.4 5.8 5 7.2 0.1 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RT_RNaseH_2 PF17919.1 GBG78127.1 - 2.8e-23 81.8 0.0 8e-23 80.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78127.1 - 2e-18 66.6 0.0 5.7e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78127.1 - 8.6e-06 25.9 0.0 2.7e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG78127.1 - 1e-05 25.3 0.3 3.2e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain tRNA-synt_1b PF00579.25 GBG78128.1 - 8.6e-08 31.8 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MMR_HSR1 PF01926.23 GBG78130.1 - 9.7e-06 25.6 0.0 5.2e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG78130.1 - 6.1e-05 23.0 0.3 0.00039 20.4 0.0 2.5 2 1 0 2 2 1 1 RsgA GTPase AAA_29 PF13555.6 GBG78130.1 - 0.00035 20.3 0.1 0.0015 18.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG78130.1 - 0.0007 20.0 0.2 0.0059 17.0 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain G-alpha PF00503.20 GBG78130.1 - 0.0018 17.5 0.0 0.0018 17.5 0.0 3.3 3 1 0 3 3 3 1 G-protein alpha subunit DUF815 PF05673.13 GBG78130.1 - 0.0022 17.2 0.0 0.016 14.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 GBG78130.1 - 0.0023 17.7 0.1 0.07 12.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain Septin PF00735.18 GBG78130.1 - 0.0043 16.4 0.1 0.0043 16.4 0.1 3.2 3 1 0 3 3 3 1 Septin AIG1 PF04548.16 GBG78130.1 - 0.0066 15.8 7.5 0.18 11.1 0.0 3.9 4 0 0 4 4 3 2 AIG1 family IIGP PF05049.13 GBG78130.1 - 0.018 14.1 0.2 0.11 11.5 0.1 2.4 1 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 GBG78130.1 - 0.02 15.2 0.5 0.12 12.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 GBG78130.1 - 0.022 15.2 0.0 0.062 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.23 GBG78130.1 - 0.022 14.8 0.1 0.022 14.8 0.1 3.7 3 2 0 3 3 2 0 Dynamin family ABC_tran PF00005.27 GBG78130.1 - 0.035 14.6 5.2 0.068 13.7 0.0 3.4 4 0 0 4 4 2 0 ABC transporter TniB PF05621.11 GBG78130.1 - 0.052 12.9 0.0 0.3 10.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein DUF1664 PF07889.12 GBG78130.1 - 0.059 13.4 0.2 0.059 13.4 0.2 3.7 5 0 0 5 5 4 0 Protein of unknown function (DUF1664) Roc PF08477.13 GBG78130.1 - 0.079 13.2 0.0 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 GBG78130.1 - 0.14 12.3 0.5 1.5 8.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain Phage_lysozyme PF00959.19 GBG78130.1 - 1.5 9.3 8.5 1.8 9.0 0.0 3.6 3 0 0 3 3 3 0 Phage lysozyme DPPIV_N PF00930.21 GBG78131.1 - 3.4e-77 259.6 0.0 4.2e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GBG78131.1 - 1.1e-49 168.9 2.4 2e-49 167.9 2.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GBG78131.1 - 1.2e-06 28.3 5.9 0.00019 21.1 3.5 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 GBG78131.1 - 1.6e-05 24.3 1.8 9.8e-05 21.7 1.8 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 GBG78131.1 - 0.0023 17.5 1.4 0.0037 16.9 0.1 1.8 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S28 PF05577.12 GBG78131.1 - 0.0034 16.3 0.1 0.0048 15.7 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Esterase PF00756.20 GBG78131.1 - 0.011 15.4 0.3 0.021 14.5 0.3 1.4 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 GBG78131.1 - 0.019 14.9 0.2 0.18 11.7 0.0 2.3 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 GBG78131.1 - 0.037 13.7 0.3 0.081 12.5 0.3 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PD40 PF07676.12 GBG78131.1 - 0.18 11.8 1.4 18 5.4 0.4 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RT_RNaseH_2 PF17919.1 GBG78132.1 - 5.2e-26 90.6 0.0 9.4e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78132.1 - 5.3e-24 84.5 0.0 9.3e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78132.1 - 2.8e-13 49.9 0.0 4.1e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG78132.1 - 0.13 12.6 12.9 0.27 11.5 12.9 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG78132.1 - 0.37 10.2 28.0 0.72 9.2 28.0 1.4 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 GBG78132.1 - 0.4 9.8 2.6 0.81 8.8 2.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2457 PF10446.9 GBG78132.1 - 1.4 7.9 23.7 2.1 7.4 23.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 GBG78132.1 - 1.7 6.7 25.9 2.6 6.1 25.9 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG78132.1 - 3.3 7.0 28.4 5.3 6.3 28.4 1.2 1 0 0 1 1 1 0 BUD22 RT_RNaseH_2 PF17919.1 GBG78133.1 - 4.3e-26 90.9 0.0 7.6e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78133.1 - 4.3e-24 84.8 0.0 7.5e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78133.1 - 2.3e-13 50.2 0.0 3.4e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG78133.1 - 0.15 12.3 13.2 0.25 11.6 13.2 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Zip PF02535.22 GBG78133.1 - 0.31 10.2 2.6 0.62 9.2 2.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.12 GBG78133.1 - 0.4 10.1 28.0 0.58 9.5 28.0 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GBG78133.1 - 1.1 8.4 23.6 1.5 7.9 23.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 GBG78133.1 - 1.4 7.0 25.9 2.1 6.5 25.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG78133.1 - 3 7.1 28.4 4.2 6.6 28.4 1.1 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 GBG78133.1 - 9.4 5.6 16.7 16 4.8 16.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ribosomal_L24e PF01246.20 GBG78134.1 - 1.1e-28 99.2 0.6 1.1e-28 99.2 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e M-inducer_phosp PF06617.13 GBG78134.1 - 0.0018 17.6 0.7 0.0018 17.6 0.7 2.0 1 1 1 2 2 2 1 M-phase inducer phosphatase MMTV_SAg PF01054.17 GBG78134.1 - 0.039 13.5 0.3 0.045 13.3 0.3 1.2 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen DUF4897 PF16238.5 GBG78134.1 - 0.064 13.1 0.2 0.078 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) RR_TM4-6 PF06459.12 GBG78134.1 - 2.4 7.9 8.0 3 7.6 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG78134.1 - 5.3 5.7 5.2 5.9 5.5 5.2 1.1 1 0 0 1 1 1 0 Presenilin DUF659 PF04937.15 GBG78135.1 - 4.6e-20 72.0 0.0 8.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78135.1 - 8.9e-06 25.4 0.1 2.1e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Prenyltransf PF01255.19 GBG78136.1 - 5.9e-77 258.2 0.0 9.4e-77 257.5 0.0 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Integrase_H2C2 PF17921.1 GBG78137.1 - 3e-19 68.9 0.3 5.3e-19 68.1 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG78137.1 - 3.7e-18 65.8 0.5 7.6e-18 64.7 0.5 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78137.1 - 1.3e-10 41.2 0.1 2.7e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG78137.1 - 0.00037 20.6 0.1 0.00078 19.6 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Lyase_1 PF00206.20 GBG78138.1 - 4.5e-118 394.2 0.0 6.2e-118 393.7 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 GBG78138.1 - 1.1e-25 89.7 0.1 2.6e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus SBP_bac_3 PF00497.20 GBG78138.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Retrotrans_gag PF03732.17 GBG78139.1 - 0.00087 19.5 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein WD40 PF00400.32 GBG78140.1 - 6.8e-06 26.7 0.3 2.3e-05 25.1 0.3 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG78140.1 - 0.013 15.8 0.3 0.031 14.6 0.2 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2282 PF10048.9 GBG78140.1 - 0.041 13.9 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) RVP_2 PF08284.11 GBG78141.1 - 8.8e-07 28.8 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78141.1 - 5e-05 23.9 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78141.1 - 0.0024 18.4 0.0 0.0057 17.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG78141.1 - 0.0071 15.9 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SlyX PF04102.12 GBG78141.1 - 0.022 15.4 0.6 0.022 15.4 0.6 3.2 3 0 0 3 3 3 0 SlyX Asp_protease PF09668.10 GBG78141.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG78142.1 - 7.7e-15 55.1 0.0 1.7e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SWI-SNF_Ssr4 PF08549.10 GBG78142.1 - 0.017 13.8 0.2 0.024 13.3 0.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) RVT_1 PF00078.27 GBG78145.1 - 1e-25 90.6 0.0 1.5e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_8 PF01501.20 GBG78146.1 - 5.2e-71 239.2 0.0 7.8e-71 238.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 GBG78146.1 - 0.00021 20.8 0.1 0.0012 18.3 0.0 2.3 2 0 0 2 2 2 1 Glucosyltransferase 24 Cnd2 PF05786.14 GBG78147.1 - 1.5e-133 447.2 0.0 1.9e-133 446.8 0.0 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 GBG78147.1 - 0.0016 18.7 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Cnd2 PF05786.14 GBG78148.1 - 5.6e-134 448.6 0.0 7.3e-134 448.2 0.0 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 GBG78148.1 - 0.0015 18.7 0.0 0.0039 17.4 0.0 1.7 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal NUDIX PF00293.28 GBG78149.1 - 2.9e-19 69.4 0.1 3.9e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Chromo PF00385.24 GBG78150.1 - 0.00022 21.0 0.1 0.00022 21.0 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG78150.1 - 0.0045 16.7 0.3 0.011 15.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG78150.1 - 0.0048 17.2 0.5 0.039 14.2 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein NiFe-hyd_HybE PF11939.8 GBG78150.1 - 0.079 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE Lipin_mid PF16876.5 GBG78150.1 - 0.081 13.1 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Porin_1 PF00267.21 GBG78150.1 - 0.18 11.2 0.1 0.25 10.7 0.1 1.1 1 0 0 1 1 1 0 Gram-negative porin Cwf_Cwc_15 PF04889.12 GBG78152.1 - 3.8 7.2 7.9 4.4 7.0 7.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRM_1 PF00076.22 GBG78153.1 - 1e-19 70.1 0.0 1.4e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GBG78153.1 - 6.8e-09 35.4 2.6 1.4e-08 34.5 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 GBG78153.1 - 0.00045 20.3 0.0 0.00089 19.3 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif zf-CCHC_3 PF13917.6 GBG78153.1 - 0.00068 19.5 0.2 0.0013 18.7 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG78153.1 - 0.0027 17.4 2.0 0.0051 16.5 2.0 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG78153.1 - 0.0032 17.2 3.3 0.0032 17.2 3.3 1.7 2 0 0 2 2 2 1 Zinc knuckle MMS19_N PF14500.6 GBG78155.1 - 3.5e-57 193.9 0.6 9.9e-56 189.2 0.0 3.4 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 GBG78155.1 - 1.3e-33 116.7 0.0 5.8e-32 111.3 0.0 3.1 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 GBG78155.1 - 0.044 14.0 9.8 1.4 9.4 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat Myb_DNA-bind_4 PF13837.6 GBG78156.1 - 4.1e-10 39.9 0.5 8.7e-10 38.9 0.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG78156.1 - 0.0074 16.6 0.4 0.031 14.6 0.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG78156.1 - 0.097 12.8 0.7 0.26 11.4 0.7 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG78157.1 - 1.1e-29 103.1 0.0 1.7e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78157.1 - 2.4e-16 60.0 0.0 3.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG78157.1 - 1.1e-05 25.2 0.0 0.078 12.6 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain TPM_phosphatase PF04536.14 GBG78158.1 - 1.5e-16 60.7 0.0 3.3e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 TPM domain RVT_1 PF00078.27 GBG78159.1 - 3e-27 95.6 0.2 5.2e-27 94.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78159.1 - 2.4e-09 37.2 0.0 5.4e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG78159.1 - 9.3e-09 35.2 0.0 2.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78159.1 - 4.2e-07 30.5 0.0 9.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78159.1 - 1.4e-05 25.5 0.0 3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease AMP-binding_C_2 PF14535.6 GBG78159.1 - 0.0075 16.6 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SlyX PF04102.12 GBG78159.1 - 0.017 15.8 0.3 0.017 15.8 0.3 3.5 4 0 0 4 4 3 0 SlyX RT_RNaseH PF17917.1 GBG78159.1 - 0.017 15.4 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase TolA_bind_tri PF16331.5 GBG78159.1 - 0.018 15.1 2.1 0.056 13.5 2.1 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation Asp_protease PF09668.10 GBG78159.1 - 0.041 13.7 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Med28 PF11594.8 GBG78159.1 - 0.12 12.5 0.2 0.52 10.4 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 28 CENP-F_leu_zip PF10473.9 GBG78159.1 - 1.4 9.0 4.6 11 6.1 3.3 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TRPM_tetra PF16519.5 GBG78159.1 - 6.5 6.9 9.2 0.89 9.7 0.2 3.1 3 1 0 3 3 3 0 Tetramerisation domain of TRPM Laminin_G_3 PF13385.6 GBG78160.1 - 0.0056 16.8 0.0 0.083 13.0 0.0 2.3 1 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_3 PF13385.6 GBG78161.1 - 0.0068 16.6 0.0 0.1 12.8 0.0 2.3 1 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_3 PF13385.6 GBG78162.1 - 0.00043 20.5 0.0 0.0009 19.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Beach PF02138.18 GBG78163.1 - 1.4e-121 405.2 0.0 1.9e-121 404.7 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GBG78163.1 - 8.5e-23 80.3 0.0 2.2e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 GBG78163.1 - 2e-14 53.5 0.2 1e-10 41.4 0.0 2.8 2 1 0 3 3 3 2 Domain of unknown function (DUF4704) WD40 PF00400.32 GBG78163.1 - 1.4e-07 32.1 1.9 0.17 12.8 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1088 PF06469.11 GBG78163.1 - 0.00061 19.5 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) Beach PF02138.18 GBG78164.1 - 1.3e-121 405.2 0.0 1.8e-121 404.7 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GBG78164.1 - 8.4e-23 80.4 0.0 2.2e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 GBG78164.1 - 1.9e-14 53.6 0.2 1e-10 41.4 0.0 2.9 2 1 0 3 3 3 2 Domain of unknown function (DUF4704) WD40 PF00400.32 GBG78164.1 - 1.3e-07 32.1 1.9 0.17 12.8 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1088 PF06469.11 GBG78164.1 - 0.0006 19.5 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) RVT_1 PF00078.27 GBG78166.1 - 1.9e-16 60.3 0.1 6e-13 48.8 0.1 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_12 PF13424.6 GBG78167.1 - 1.1e-10 41.6 3.4 0.00019 21.6 0.4 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 GBG78167.1 - 9.7e-09 34.5 7.5 1.5e-08 33.9 0.1 3.1 3 0 0 3 3 3 1 SHNi-TPR TPR_1 PF00515.28 GBG78167.1 - 1.5e-07 30.9 1.6 0.0056 16.5 0.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG78167.1 - 7.3e-05 22.6 9.2 0.11 12.7 1.7 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG78167.1 - 0.00024 20.9 1.0 1.6 8.9 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG78167.1 - 0.0026 17.4 0.3 0.033 13.9 0.1 2.5 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 GBG78167.1 - 0.028 15.1 2.6 0.028 15.1 2.6 4.3 4 2 0 4 4 4 0 Tetratricopeptide repeat DUF2064 PF09837.9 GBG78167.1 - 0.054 13.3 0.3 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) TPR_9 PF13371.6 GBG78167.1 - 0.25 11.5 4.6 16 5.7 0.6 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG78167.1 - 1.5 9.9 8.2 1.5 9.8 0.8 4.1 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG78167.1 - 2.6 8.5 9.5 1.4 9.3 1.0 3.8 5 0 0 5 5 4 0 Tetratricopeptide repeat GCK PF07802.11 GBG78168.1 - 9.7e-21 74.0 6.5 1.9e-20 73.0 6.5 1.5 1 0 0 1 1 1 1 GCK domain CX9C PF16860.5 GBG78168.1 - 0.00024 21.0 1.5 0.00049 20.0 1.5 1.5 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ATP-synt_S1 PF05827.12 GBG78169.1 - 0.047 13.5 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) MCM3AP_GANP PF16769.5 GBG78169.1 - 0.18 10.1 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP zf-CCHC PF00098.23 GBG78170.1 - 2.2e-08 33.8 2.1 3.9e-08 33.0 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG78170.1 - 0.0065 16.1 1.5 0.014 15.1 1.5 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Sigma70_ner PF04546.13 GBG78170.1 - 0.0071 16.3 6.4 0.011 15.6 6.4 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF3523 PF12037.8 GBG78170.1 - 0.67 9.3 19.8 0.032 13.6 14.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) Borrelia_P83 PF05262.11 GBG78170.1 - 1.7 7.0 9.7 1.9 6.9 9.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Phlebovirus_NSM PF07246.11 GBG78170.1 - 2.6 7.3 9.4 3.8 6.8 9.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M OmpH PF03938.14 GBG78170.1 - 2.6 8.4 16.5 6 7.2 16.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FHIPEP PF00771.20 GBG78170.1 - 6.2 5.2 5.4 8.3 4.7 5.4 1.1 1 0 0 1 1 1 0 FHIPEP family GNAT_acetyltr_2 PF13718.6 GBG78170.1 - 8.8 5.7 6.0 15 4.9 6.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Lipase_GDSL_2 PF13472.6 GBG78171.1 - 0.038 14.4 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family PASTA PF03793.19 GBG78172.1 - 0.076 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 PASTA domain Asparaginase_C PF17763.1 GBG78172.1 - 0.082 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain VIGSSK PF14773.6 GBG78172.1 - 0.8 9.9 0.1 0.8 9.9 0.1 2.9 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal RT_RNaseH_2 PF17919.1 GBG78173.1 - 8.2e-27 93.2 0.0 1.3e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78173.1 - 1.8e-22 79.6 0.0 3.2e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78173.1 - 1e-10 41.5 0.1 1.5e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG78173.1 - 1.2 7.4 9.0 1.6 6.9 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG78173.1 - 2.2 7.6 9.8 3 7.2 9.8 1.1 1 0 0 1 1 1 0 SDA1 SH3_15 PF18346.1 GBG78174.1 - 1.8e-85 281.2 38.1 3.9e-10 39.9 0.1 14.6 12 2 0 12 12 12 12 Mind bomb SH3 repeat domain RVT_1 PF00078.27 GBG78174.1 - 2.2e-09 37.2 0.0 3.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Es2 PF09751.9 GBG78174.1 - 0.013 15.3 13.1 0.025 14.3 13.1 1.3 1 0 0 1 1 1 0 Nuclear protein Es2 TMEM174 PF15029.6 GBG78174.1 - 0.044 13.5 0.0 16 5.1 0.0 4.1 4 0 0 4 4 4 0 Transmembrane protein 174 NHase_beta PF02211.15 GBG78174.1 - 0.14 12.1 11.6 19 5.2 0.0 6.5 9 1 0 9 9 9 0 Nitrile hydratase beta subunit Pkinase_Tyr PF07714.17 GBG78175.1 - 1.9e-15 56.8 0.1 3e-15 56.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG78175.1 - 5.9e-15 55.3 0.0 9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SpoIIIAH PF12685.7 GBG78175.1 - 0.0027 17.6 16.2 39 4.0 16.2 9.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Neur_chan_memb PF02932.16 GBG78175.1 - 0.33 11.0 10.3 7.5e+03 -3.3 10.3 9.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF755 PF05501.11 GBG78175.1 - 0.5 10.7 11.8 1e+04 -3.2 11.8 9.9 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Plasmodium_Vir PF05795.11 GBG78175.1 - 2.2 7.6 14.4 4.9e+02 -0.1 14.4 5.9 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLC12 PF03522.15 GBG78175.1 - 3 6.7 18.4 2.4e+03 -2.8 18.4 6.8 1 0 0 1 1 1 0 Solute carrier family 12 Lzipper-MIP1 PF14389.6 GBG78176.1 - 0.18 12.1 5.1 1.7 9.0 0.2 3.0 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 THOC7 PF05615.13 GBG78176.1 - 0.29 11.4 16.7 0.23 11.7 0.7 2.6 3 0 0 3 3 3 0 Tho complex subunit 7 DUF2458 PF10454.9 GBG78176.1 - 0.34 10.6 11.5 0.042 13.5 6.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) MbeD_MobD PF04899.12 GBG78176.1 - 0.34 11.0 7.4 0.18 11.9 0.5 3.1 3 1 0 3 3 3 0 MbeD/MobD like DUF641 PF04859.12 GBG78176.1 - 0.79 10.1 12.7 0.29 11.5 1.1 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Relaxase PF03432.14 GBG78176.1 - 2.4 7.7 9.6 1.1 8.9 4.2 2.1 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain XhlA PF10779.9 GBG78176.1 - 6.5 7.0 8.3 0.78 10.0 1.3 2.6 2 1 1 3 3 3 0 Haemolysin XhlA zf-CCHC PF00098.23 GBG78177.1 - 8.2e-06 25.7 1.0 1.8e-05 24.6 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF4614 PF15391.6 GBG78177.1 - 7.9 6.4 7.4 22 5.0 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4614) zf-CCHC PF00098.23 GBG78178.1 - 1.7 8.8 9.3 3.1 8.0 9.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG78179.1 - 6e-05 22.9 2.1 0.00021 21.2 2.1 2.0 1 0 0 1 1 1 1 Zinc knuckle DBD_Tnp_Mut PF03108.15 GBG78179.1 - 0.032 14.2 0.1 0.095 12.7 0.1 1.8 1 0 0 1 1 1 0 MuDR family transposase DUF4192 PF13830.6 GBG78179.1 - 0.076 13.1 4.4 0.13 12.3 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Presenilin PF01080.17 GBG78181.1 - 1.3 7.7 6.9 1.8 7.3 6.9 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG78181.1 - 5.2 5.1 15.1 6.4 4.9 15.1 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_15 PF13175.6 GBG78182.1 - 0.036 13.8 1.9 0.036 13.8 1.9 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF4407 PF14362.6 GBG78182.1 - 0.47 9.8 9.6 0.54 9.6 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop14 PF04147.12 GBG78182.1 - 1.8 6.7 17.8 2.1 6.4 17.8 1.0 1 0 0 1 1 1 0 Nop14-like family 5_nucleotid PF05761.14 GBG78182.1 - 5.9 5.7 7.3 7.5 5.3 7.3 1.0 1 0 0 1 1 1 0 5' nucleotidase family CDC45 PF02724.14 GBG78184.1 - 0.033 12.5 14.5 0.042 12.2 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG78184.1 - 0.059 12.8 21.4 0.083 12.3 21.4 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG78184.1 - 0.28 9.4 21.1 0.36 9.0 21.1 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG78184.1 - 0.53 9.0 10.9 0.73 8.5 10.9 1.1 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GBG78184.1 - 1.5 8.1 20.9 2.2 7.5 20.9 1.2 1 0 0 1 1 1 0 BUD22 PGA2 PF07543.12 GBG78184.1 - 1.6 8.7 17.5 3.1 7.8 17.5 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 SpoIIIAH PF12685.7 GBG78184.1 - 4.6 7.0 9.9 6.9 6.4 9.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DDE_Tnp_4 PF13359.6 GBG78185.1 - 6.5e-17 61.6 0.0 2.7e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78185.1 - 2.3e-05 24.1 0.0 4.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG78185.1 - 0.069 13.5 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 Transposase DDE domain HTH_48 PF17906.1 GBG78185.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 HTH domain in Mos1 transposase EMC1_C PF07774.13 GBG78188.1 - 0.31 10.7 0.3 0.96 9.1 0.0 1.7 2 0 0 2 2 2 0 ER membrane protein complex subunit 1, C-terminal EB1 PF03271.17 GBG78191.1 - 0.00031 20.9 0.0 0.00096 19.4 0.0 1.8 1 1 0 1 1 1 1 EB1-like C-terminal motif Trypan_PARP PF05887.11 GBG78192.1 - 0.0021 18.0 5.1 0.0021 18.0 5.1 2.6 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) PBP1_TM PF14812.6 GBG78192.1 - 0.0036 17.6 6.5 0.01 16.2 6.5 1.7 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 GBG78192.1 - 3.5 5.8 6.4 5.1 5.3 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Mucin PF01456.17 GBG78193.1 - 0.0026 17.8 1.9 0.0041 17.1 1.9 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.12 GBG78193.1 - 0.005 14.9 20.0 0.0061 14.6 20.0 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 GBG78193.1 - 0.0093 15.9 0.7 0.016 15.2 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) CbiG_mid PF11761.8 GBG78193.1 - 0.05 13.7 0.0 0.093 12.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis central region SLC12 PF03522.15 GBG78193.1 - 0.21 10.6 7.9 0.24 10.4 7.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Serinc PF03348.15 GBG78193.1 - 1.5 7.7 3.0 1.7 7.5 3.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Med13_C PF06333.12 GBG78193.1 - 1.8 7.8 6.3 2.1 7.5 6.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain O-antigen_lig PF13425.6 GBG78193.1 - 2 7.1 7.3 2.3 6.9 7.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ABC2_membrane_3 PF12698.7 GBG78193.1 - 5.9 5.9 10.4 6.8 5.7 10.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RT_RNaseH_2 PF17919.1 GBG78194.1 - 9.6e-36 121.8 0.0 1.6e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78194.1 - 8.5e-33 112.8 0.0 1.3e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase_Tyr PF07714.17 GBG78195.1 - 8.5e-35 120.3 0.0 3.9e-33 114.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG78195.1 - 2.7e-34 118.7 0.0 4.6e-22 78.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain PRIMA1 PF16101.5 GBG78195.1 - 0.031 14.3 10.4 0.071 13.2 10.4 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SR-25 PF10500.9 GBG78195.1 - 0.72 9.4 9.7 0.13 11.8 1.0 2.8 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein GTP_EFTU PF00009.27 GBG78197.1 - 5.9e-52 176.0 0.0 1e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GBG78197.1 - 1.1e-20 73.5 0.0 2.3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 GBG78197.1 - 6.7e-07 29.4 0.4 1.4e-06 28.3 0.4 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 GBG78197.1 - 6.5e-05 22.9 0.0 0.00015 21.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Septin PF00735.18 GBG78197.1 - 0.00089 18.6 0.1 0.0015 17.9 0.1 1.2 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 GBG78197.1 - 0.0012 18.4 0.2 0.051 13.1 0.1 3.5 4 1 0 4 4 4 1 Ferrous iron transport protein B Roc PF08477.13 GBG78197.1 - 0.034 14.4 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG78197.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family SRPRB PF09439.10 GBG78197.1 - 0.1 12.0 0.1 0.38 10.2 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TMEM219 PF14940.6 GBG78197.1 - 0.15 11.6 2.9 0.26 10.8 2.9 1.3 1 0 0 1 1 1 0 Transmembrane 219 Pkinase_Tyr PF07714.17 GBG78198.1 - 1.2e-32 113.3 0.0 4.3e-31 108.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG78198.1 - 3e-32 112.1 0.0 3.7e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Trp_oprn_chp PF09534.10 GBG78198.1 - 0.0079 16.0 0.3 0.017 15.0 0.3 1.5 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ABC1 PF03109.16 GBG78198.1 - 0.017 15.3 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family zf-C3HC4_2 PF13923.6 GBG78198.1 - 0.8 9.6 2.3 1.6 8.6 2.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BUD22 PF09073.10 GBG78199.1 - 0.27 10.6 24.0 0.36 10.1 24.0 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG78199.1 - 0.28 9.4 18.3 0.41 8.9 18.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG78199.1 - 0.49 9.8 22.8 0.66 9.3 22.8 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG78199.1 - 0.98 8.1 5.9 1.2 7.9 5.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG78199.1 - 1.2 7.2 24.2 1.6 6.8 24.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 GBG78199.1 - 5.2 6.4 24.4 7.2 5.9 24.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pkinase_Tyr PF07714.17 GBG78200.1 - 2.9e-31 108.7 0.0 4.9e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG78200.1 - 4.5e-31 108.2 0.0 9.4e-20 71.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain ABC1 PF03109.16 GBG78200.1 - 0.067 13.4 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 ABC1 family DDE_Tnp_4 PF13359.6 GBG78201.1 - 4.7e-09 36.1 0.0 7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78201.1 - 0.0007 19.2 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DUF3446 PF11928.8 GBG78202.1 - 0.034 14.4 6.8 0.088 13.1 6.8 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain Pkinase PF00069.25 GBG78203.1 - 1.4e-32 113.1 0.0 3.1e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG78203.1 - 1e-28 100.4 0.0 7.9e-28 97.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PRIMA1 PF16101.5 GBG78203.1 - 0.014 15.4 4.4 0.014 15.4 4.4 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 APH PF01636.23 GBG78203.1 - 0.035 14.0 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 GBG78203.1 - 0.041 14.0 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family zf-CCHC PF00098.23 GBG78204.1 - 0.21 11.7 0.1 0.39 10.9 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle cNMP_binding PF00027.29 GBG78205.1 - 8.3e-06 25.8 0.0 2.3e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Scramblase PF03803.15 GBG78206.1 - 5.2e-55 186.1 0.0 7.4e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Scramblase Tetraspanin PF00335.20 GBG78207.1 - 6.8e-33 114.3 9.1 8.3e-33 114.0 9.1 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 GBG78207.1 - 0.071 11.9 4.6 0.19 10.4 2.9 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) YfhO PF09586.10 GBG78207.1 - 0.15 10.3 0.7 0.21 9.8 0.7 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SIT PF15330.6 GBG78207.1 - 0.16 12.5 0.6 1.1 9.8 0.1 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT LtrA PF06772.11 GBG78207.1 - 0.41 9.8 10.3 0.033 13.4 5.6 1.4 2 0 0 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) DUF1772 PF08592.11 GBG78207.1 - 1 9.7 8.1 0.92 9.8 4.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Cytochrom_B_C PF00032.17 GBG78207.1 - 1.4 9.3 4.7 0.85 9.9 2.1 1.9 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF92 PF01940.16 GBG78209.1 - 1.2e-42 145.9 17.8 3.1e-42 144.6 17.8 1.7 1 0 0 1 1 1 1 Integral membrane protein DUF92 Glycos_transf_2 PF00535.26 GBG78209.1 - 9.9e-23 80.8 0.1 3.8e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GBG78209.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 GBG78209.1 - 0.00035 20.5 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Sensor PF13796.6 GBG78210.1 - 0.028 14.5 0.2 0.039 14.0 0.2 1.1 1 0 0 1 1 1 0 Putative sensor DUF4586 PF15239.6 GBG78211.1 - 2e-12 47.9 0.4 2.9e-12 47.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) RVT_1 PF00078.27 GBG78212.1 - 6.4e-08 32.4 0.1 0.0043 16.6 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) IQ PF00612.27 GBG78213.1 - 1.8e-17 61.4 13.5 3.6e-06 26.3 0.7 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif FmdE PF02663.14 GBG78213.1 - 1.3 9.0 3.3 0.56 10.3 0.3 1.9 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon RVT_1 PF00078.27 GBG78214.1 - 1.6e-23 83.4 0.1 3.6e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78214.1 - 4.6e-18 65.1 0.1 1.6e-17 63.3 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG78214.1 - 1.3e-10 41.5 0.1 1.9e-09 37.7 0.2 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78214.1 - 5.2e-08 33.1 0.0 2.1e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG78214.1 - 2.4e-07 30.7 0.0 0.0052 16.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG78214.1 - 0.009 16.3 1.6 0.027 14.7 0.4 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG78214.1 - 0.11 12.7 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG78216.1 - 5e-05 23.2 2.3 0.00013 21.8 2.3 1.8 1 0 0 1 1 1 1 Zinc knuckle SLD5_C PF16922.5 GBG78216.1 - 0.061 13.5 0.1 0.32 11.2 0.1 2.3 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus Mit_ribos_Mrp51 PF11709.8 GBG78216.1 - 0.083 12.5 2.8 0.15 11.7 2.8 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit HrcA PF01628.21 GBG78216.1 - 0.12 12.2 3.5 0.28 11.0 3.5 1.5 1 0 0 1 1 1 0 HrcA protein C terminal domain DUF3292 PF11696.8 GBG78216.1 - 0.33 9.3 6.7 0.46 8.8 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) zf-CCHC_2 PF13696.6 GBG78216.1 - 0.99 9.3 5.4 0.22 11.4 1.8 1.8 2 0 0 2 2 2 0 Zinc knuckle DUF4192 PF13830.6 GBG78216.1 - 2.1 8.4 11.7 6.4 6.7 9.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) ASH PF15780.5 GBG78217.1 - 3.9e-06 27.0 0.0 0.0019 18.4 0.0 2.2 1 1 1 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MYCBPAP PF14646.6 GBG78217.1 - 9.4e-05 21.5 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 MYCBP-associated protein family PapD-like PF14874.6 GBG78217.1 - 0.0014 18.7 0.0 0.025 14.7 0.0 2.1 2 0 0 2 2 2 1 Flagellar-associated PapD-like DUF1573 PF07610.11 GBG78217.1 - 0.0043 17.1 0.0 0.52 10.4 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1573) PapD-like PF14874.6 GBG78218.1 - 3.7e-12 46.3 0.8 0.00012 22.2 0.1 4.1 5 0 0 5 5 5 3 Flagellar-associated PapD-like ASH PF15780.5 GBG78218.1 - 8.5e-08 32.3 4.8 1.1 9.5 0.0 5.9 6 0 0 6 6 6 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 GBG78218.1 - 5.5e-05 23.0 0.0 2.2 8.2 0.0 4.8 5 0 0 5 5 5 1 MSP (Major sperm protein) domain DUF1573 PF07610.11 GBG78218.1 - 0.15 12.1 0.0 86 3.3 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1573) DUF3498 PF12004.8 GBG78218.1 - 2.6 7.1 3.7 37 3.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3498) MCM_bind PF09739.9 GBG78220.1 - 0.098 11.1 4.2 0.12 10.7 4.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SDA1 PF05285.12 GBG78220.1 - 0.17 11.3 20.9 0.21 11.0 20.9 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 GBG78220.1 - 0.97 9.1 9.0 1.1 8.8 9.0 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PPL5 PF18168.1 GBG78220.1 - 1.1 8.5 3.8 1.4 8.2 3.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 LAP1C PF05609.12 GBG78220.1 - 1.8 7.5 8.1 2 7.4 8.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG78220.1 - 1.8 6.6 23.2 2.2 6.4 23.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG78220.1 - 4.6 5.4 20.1 5.8 5.1 20.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG78221.1 - 3.9e-17 62.1 0.0 1.2e-16 60.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78221.1 - 9.1e-08 32.3 0.0 2.9e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78221.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NusB PF01029.18 GBG78221.1 - 0.11 12.7 3.3 0.11 12.7 1.1 2.1 1 1 1 2 2 2 0 NusB family Peptidase_M32 PF02074.15 GBG78221.1 - 0.13 11.0 10.0 0.27 10.0 10.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Sporozoite_P67 PF05642.11 GBG78221.1 - 0.77 7.8 6.7 1.7 6.7 6.7 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen V_ATPase_I PF01496.19 GBG78221.1 - 1 7.2 11.1 1.7 6.4 6.8 2.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2937 PF11157.8 GBG78221.1 - 5.5 6.7 11.6 0.64 9.7 3.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Symplekin_C PF12295.8 GBG78223.1 - 0.013 15.6 0.1 0.061 13.4 0.1 2.0 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal DNA_pack_N PF02500.15 GBG78223.1 - 0.043 13.6 0.2 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus DUF3301 PF11743.8 GBG78223.1 - 0.14 11.9 0.7 0.26 11.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) DUF4763 PF15960.5 GBG78223.1 - 0.16 11.3 10.6 0.35 10.1 8.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Casc1_N PF15927.5 GBG78223.1 - 0.19 11.4 9.5 0.43 10.2 9.5 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF1664 PF07889.12 GBG78223.1 - 0.44 10.6 7.2 0.15 12.1 3.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 GBG78223.1 - 0.64 9.2 3.4 1.1 8.5 3.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.16 GBG78223.1 - 6.6 7.3 9.6 6.8 7.2 7.7 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 ADIP PF11559.8 GBG78223.1 - 9.6 6.3 17.5 2.9 8.0 13.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding RVT_1 PF00078.27 GBG78224.1 - 8.9e-27 94.0 0.1 2.3e-26 92.7 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG78224.1 - 3e-07 30.3 0.0 6.2e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG78224.1 - 0.0016 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG78224.1 - 0.0031 18.1 0.0 0.0095 16.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78224.1 - 0.0067 17.0 0.0 0.019 15.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease GAS PF13851.6 GBG78224.1 - 0.36 10.1 9.4 0.035 13.4 1.3 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 GBG78224.1 - 1.7 8.7 10.6 0.089 12.8 2.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 GBG78224.1 - 3.9 7.2 7.8 0.25 11.1 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 GBG78224.1 - 3.9 6.3 10.9 0.19 10.5 1.4 2.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Tup_N PF08581.10 GBG78224.1 - 6.5 7.1 12.0 0.35 11.2 2.9 3.3 3 0 0 3 3 2 0 Tup N-terminal YabA PF06156.13 GBG78224.1 - 9.1 7.0 7.7 31 5.3 0.0 3.4 3 0 0 3 3 2 0 Initiation control protein YabA rve PF00665.26 GBG78225.1 - 1.8e-14 53.9 0.1 8.5e-14 51.8 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78225.1 - 1e-12 47.9 0.0 2.5e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain UPF0184 PF03670.13 GBG78225.1 - 0.056 13.8 0.3 0.14 12.5 0.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) DAG_kinase_N PF14513.6 GBG78225.1 - 1.4 9.1 6.7 0.17 12.1 0.4 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus SR-25 PF10500.9 GBG78225.1 - 4.2 6.9 15.9 1.2 8.7 6.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Retrotrans_gag PF03732.17 GBG78226.1 - 0.0015 18.7 0.1 0.0075 16.5 0.1 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein DUF4611 PF15387.6 GBG78226.1 - 0.17 12.1 4.3 0.39 11.0 4.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Utp12 PF04003.12 GBG78227.1 - 0.0027 18.0 0.1 0.006 16.9 0.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nodulin PF02451.15 GBG78227.1 - 0.11 11.9 1.0 0.2 11.1 0.2 1.8 2 0 0 2 2 2 0 Nodulin Pyrophosphatase PF00719.19 GBG78228.1 - 2.5e-51 173.7 1.2 3.1e-51 173.3 0.2 1.7 2 0 0 2 2 2 1 Inorganic pyrophosphatase HMGL-like PF00682.19 GBG78228.1 - 2.9e-44 151.6 0.1 8.2e-44 150.1 0.0 1.8 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 GBG78228.1 - 7.9e-21 74.3 0.1 2.8e-20 72.6 0.0 1.9 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain LRR_6 PF13516.6 GBG78230.1 - 7.7e-13 47.4 2.4 0.037 14.1 0.0 8.3 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 GBG78230.1 - 0.0053 17.1 4.1 1.3e+02 3.7 0.0 6.4 6 0 0 6 6 6 0 Leucine Rich Repeat UPF0254 PF06787.11 GBG78230.1 - 0.19 11.5 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Fer4_23 PF18009.1 GBG78230.1 - 0.52 10.8 3.3 0.56 10.7 1.3 2.0 2 0 0 2 2 2 0 4Fe-4S iron-sulfur cluster binding domain Fasciclin PF02469.22 GBG78231.1 - 0.0012 19.1 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 GBG78232.1 - 0.0083 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain 2-oxogl_dehyd_N PF16078.5 GBG78232.1 - 0.14 11.8 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus DEC-1_N PF04625.13 GBG78234.1 - 1.3 7.9 7.0 2.1 7.3 7.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RL10P_insert PF17777.1 GBG78236.1 - 1.7e-24 85.6 0.0 4.3e-24 84.3 0.0 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 GBG78236.1 - 2e-14 53.5 0.0 3.1e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 TIM PF00121.18 GBG78239.1 - 8.1e-89 297.2 0.3 9.2e-89 297.0 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Acid_PPase PF12689.7 GBG78240.1 - 2.4e-37 128.4 0.4 3.1e-30 105.2 0.0 2.2 1 1 1 2 2 2 2 Acid Phosphatase HAD_2 PF13419.6 GBG78240.1 - 2e-07 31.2 0.0 2.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GBG78240.1 - 0.033 14.5 0.0 0.056 13.7 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Wtap PF17098.5 GBG78241.1 - 0.016 15.2 3.0 0.024 14.5 3.0 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family zf-CCHC PF00098.23 GBG78241.1 - 0.024 14.7 0.5 0.04 14.0 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Herpes_UL87 PF03043.14 GBG78241.1 - 0.15 10.5 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family ALMT PF11744.8 GBG78241.1 - 0.43 9.4 1.3 0.61 8.8 1.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter RT_RNaseH PF17917.1 GBG78242.1 - 2.8e-54 181.8 0.0 4.3e-32 110.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78242.1 - 6.2e-48 161.0 0.0 6.1e-35 119.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78242.1 - 2.7e-45 154.6 0.4 3.1e-30 105.4 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78242.1 - 2.3e-12 46.8 0.1 1.7e-11 44.1 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78242.1 - 6.2e-05 23.1 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG78242.1 - 0.13 12.1 0.2 1.9 8.3 0.0 2.7 3 0 0 3 3 3 0 Reverse transcriptase-like SOUL PF04832.12 GBG78243.1 - 3.1e-47 160.8 5.3 5.5e-26 91.7 1.6 3.1 2 1 0 2 2 2 2 SOUL heme-binding protein Axin_b-cat_bind PF08833.10 GBG78243.1 - 0.024 14.7 4.2 0.06 13.5 4.2 1.7 1 0 0 1 1 1 0 Axin beta-catenin binding domain DUF563 PF04577.14 GBG78244.1 - 4.9e-17 62.8 0.0 8e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RVT_1 PF00078.27 GBG78245.1 - 1.3e-35 123.0 0.1 2e-35 122.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 GBG78245.1 - 1.8 7.3 4.9 2.8 6.6 4.9 1.2 1 0 0 1 1 1 0 Presenilin RNase_PH PF01138.21 GBG78246.1 - 1.4e-27 96.8 0.0 2.4e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GBG78246.1 - 1.1e-07 31.7 0.0 2.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TPR_MLP1_2 PF07926.12 GBG78247.1 - 0.0033 17.5 37.0 0.26 11.4 19.6 2.5 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 GBG78247.1 - 0.0065 16.7 5.7 0.0065 16.7 5.7 3.3 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding PCRF PF03462.18 GBG78247.1 - 0.0075 16.2 4.0 0.0075 16.2 4.0 2.2 1 1 1 2 2 2 1 PCRF domain ATG16 PF08614.11 GBG78247.1 - 0.011 16.0 14.1 0.011 16.0 14.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 GBG78247.1 - 0.019 15.6 35.7 0.14 12.8 1.9 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 GBG78247.1 - 0.022 15.2 28.5 0.069 13.6 16.1 2.1 1 1 1 2 2 2 0 Fez1 Surfac_D-trimer PF09006.11 GBG78247.1 - 0.097 12.6 10.1 0.16 11.9 1.5 3.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Spc7 PF08317.11 GBG78247.1 - 0.16 10.8 29.7 0.36 9.6 10.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein BAR_2 PF10455.9 GBG78247.1 - 0.31 10.1 10.9 0.47 9.6 3.1 2.2 1 1 1 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4407 PF14362.6 GBG78247.1 - 0.36 10.1 24.3 8.4 5.6 4.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) THOC7 PF05615.13 GBG78247.1 - 0.38 11.0 30.6 42 4.4 24.7 3.4 1 1 1 2 2 2 0 Tho complex subunit 7 Fungal_TACC PF12709.7 GBG78247.1 - 0.4 11.2 17.3 1.2 9.7 0.2 4.7 1 1 5 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins Leu_zip PF15294.6 GBG78247.1 - 0.45 10.0 23.5 0.76 9.2 12.2 2.1 1 1 1 2 2 2 0 Leucine zipper IFT57 PF10498.9 GBG78247.1 - 0.75 8.7 21.0 0.92 8.4 3.2 2.1 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 MHB PF16525.5 GBG78247.1 - 0.78 10.0 9.1 5.5 7.3 0.1 3.2 2 1 1 3 3 3 0 Haemophore, haem-binding TFIIA PF03153.13 GBG78247.1 - 1.3 9.0 18.7 1.8 8.5 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRKG1_interact PF15898.5 GBG78247.1 - 1.3 10.0 28.5 0.65 10.9 8.1 3.7 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain MAD PF05557.13 GBG78247.1 - 2 6.7 30.2 4.1 5.7 30.2 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein NBP1 PF08537.10 GBG78247.1 - 2.2 7.6 11.5 2.8 7.2 11.5 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Spc29 PF17082.5 GBG78247.1 - 2.2 8.0 11.3 8.2 6.2 11.1 1.9 1 1 0 1 1 1 0 Spindle Pole Component 29 GAS PF13851.6 GBG78247.1 - 2.2 7.6 31.4 3.6 6.9 8.0 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding betaPIX_CC PF16523.5 GBG78247.1 - 2.3 8.1 16.0 2.5 8.0 3.1 3.3 1 1 1 3 3 3 0 betaPIX coiled coil Phage_GP20 PF06810.11 GBG78247.1 - 3.8 7.3 15.6 6 6.7 1.9 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Cep57_CLD_2 PF14197.6 GBG78247.1 - 4.4 7.5 29.7 0.092 12.8 3.7 4.8 1 1 4 5 5 5 0 Centrosome localisation domain of PPC89 DUF2408 PF10303.9 GBG78247.1 - 4.9 7.7 15.1 6e+02 1.0 15.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) BLOC1_2 PF10046.9 GBG78247.1 - 5.7 7.3 17.7 1.9 8.9 2.1 3.6 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 GBG78247.1 - 5.8 7.0 32.0 2.3 8.3 4.4 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 GBG78247.1 - 6.6 6.8 16.6 0.089 12.8 5.9 2.5 1 1 1 2 2 2 0 Laminin Domain II YscO PF07321.12 GBG78247.1 - 6.7 6.7 37.1 16 5.4 9.4 2.6 1 1 1 2 2 2 0 Type III secretion protein YscO CENP-F_leu_zip PF10473.9 GBG78247.1 - 8.8 6.4 30.3 53 3.8 15.8 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.14 GBG78247.1 - 9.2 6.6 38.0 0.61 10.4 6.3 3.0 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) CSN8_PSD8_EIF3K PF10075.9 GBG78248.1 - 5.4e-22 78.3 0.0 7.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TLP-20 PF06088.11 GBG78250.1 - 0.092 12.6 3.4 0.79 9.6 3.4 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Rhomboid PF01694.22 GBG78251.1 - 2.9e-22 79.3 14.5 5.7e-22 78.3 14.5 1.5 1 0 0 1 1 1 1 Rhomboid family UBA PF00627.31 GBG78251.1 - 7.7e-11 41.7 0.5 1.4e-10 40.9 0.5 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Potass_KdpF PF09604.10 GBG78251.1 - 0.017 15.1 1.6 0.086 12.8 1.6 2.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) DUF4268 PF14088.6 GBG78251.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) DUF1751 PF08551.10 GBG78251.1 - 0.18 12.4 1.9 0.19 12.3 0.5 1.8 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) SDA1 PF05285.12 GBG78252.1 - 0.011 15.2 36.9 0.014 14.9 36.9 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG78252.1 - 0.94 8.7 36.5 1.1 8.5 36.5 1.1 1 0 0 1 1 1 0 BUD22 Myb_DNA-binding PF00249.31 GBG78253.1 - 2.4e-07 30.8 0.0 7.1e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3042 PF11240.8 GBG78253.1 - 2.8 8.0 0.0 2.8 8.0 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3042) Myb_DNA-binding PF00249.31 GBG78254.1 - 2.9e-07 30.6 0.0 7e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Spore_coat_CotO PF14153.6 GBG78254.1 - 0.0075 16.2 6.3 0.0075 16.2 6.3 5.1 2 1 2 4 4 4 1 Spore coat protein CotO DUF3042 PF11240.8 GBG78254.1 - 2.8 8.0 0.0 2.8 8.0 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3042) Myb_DNA-binding PF00249.31 GBG78255.1 - 2.9e-07 30.6 0.0 7e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Spore_coat_CotO PF14153.6 GBG78255.1 - 0.0075 16.2 6.3 0.0075 16.2 6.3 5.1 2 1 2 4 4 4 1 Spore coat protein CotO DUF3042 PF11240.8 GBG78255.1 - 2.8 8.0 0.0 2.8 8.0 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3042) DIRP PF06584.13 GBG78256.1 - 6e-28 97.1 0.0 1.1e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 DIRP RT_RNaseH_2 PF17919.1 GBG78257.1 - 4.4e-28 97.2 0.0 7.7e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78257.1 - 3.8e-23 81.8 0.0 7.1e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78257.1 - 5.9e-11 42.3 0.4 9.3e-11 41.7 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG78257.1 - 0.26 10.7 8.3 0.46 9.9 8.3 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG78257.1 - 0.39 8.9 9.7 0.48 8.6 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG78257.1 - 1.6 6.9 9.8 2.3 6.4 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein PapC_C PF13953.6 GBG78258.1 - 0.0022 17.7 26.9 8.7 6.2 0.2 7.7 1 1 9 10 10 10 5 PapC C-terminal domain RTA1 PF04479.13 GBG78258.1 - 0.0054 16.4 10.3 21 4.7 0.0 6.7 2 2 6 9 9 9 1 RTA1 like protein ORF_2_N PF18492.1 GBG78258.1 - 0.1 12.8 0.0 36 4.6 0.0 3.7 2 1 1 4 4 4 0 Open reading frame 2 N-terminal domain SH3_19 PF18597.1 GBG78258.1 - 0.21 11.5 35.3 11 5.9 0.1 8.9 10 0 0 10 10 10 0 Myosin X N-terminal SH3 domain Methyltransf_1N PF02870.15 GBG78258.1 - 0.22 12.3 7.0 82 4.1 0.1 5.7 4 2 1 5 5 5 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DdrB PF12747.7 GBG78258.1 - 7.9 6.3 19.1 51 3.7 0.2 6.0 1 1 5 7 7 7 0 DdrB-like protein Morc6_S5 PF17942.1 GBG78259.1 - 3.8e-37 127.4 0.2 8.1e-22 77.8 0.0 2.3 1 1 1 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like HATPase_c_3 PF13589.6 GBG78259.1 - 1e-14 54.5 0.0 2.2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GBG78259.1 - 2.4e-05 24.8 2.4 0.00031 21.2 0.0 2.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Leu_zip PF15294.6 GBG78259.1 - 0.13 11.8 3.0 0.2 11.2 3.0 1.2 1 0 0 1 1 1 0 Leucine zipper ZapB PF06005.12 GBG78259.1 - 7.4 7.1 7.9 24 5.5 7.9 1.9 1 1 0 1 1 1 0 Cell division protein ZapB HAD_2 PF13419.6 GBG78260.1 - 7.1e-07 29.5 0.0 8.5e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GBG78260.1 - 0.005 17.2 0.0 0.049 13.9 0.0 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase NT5C PF06941.12 GBG78260.1 - 0.03 14.2 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_like PF13242.6 GBG78261.1 - 0.003 17.6 0.0 0.038 14.1 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 GBG78261.1 - 0.027 14.5 0.2 0.083 13.0 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NHL PF01436.21 GBG78262.1 - 4.1e-33 111.7 0.0 1.5e-05 24.8 0.0 6.5 6 0 0 6 6 6 6 NHL repeat SGL PF08450.12 GBG78262.1 - 3.2e-11 43.3 0.7 0.013 15.1 0.1 4.5 3 1 1 5 5 5 3 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 GBG78262.1 - 4.8e-07 29.9 0.0 0.92 9.7 0.0 5.6 6 0 0 6 6 6 2 Arylesterase DUF5128 PF17170.4 GBG78262.1 - 0.00013 21.2 0.5 0.02 14.1 0.1 3.1 4 0 0 4 4 4 1 6-bladed beta-propeller GTP1_OBG PF01018.22 GBG78262.1 - 0.00062 19.4 4.3 0.014 15.0 0.9 2.7 2 1 1 3 3 3 2 GTP1/OBG Phytase-like PF13449.6 GBG78262.1 - 0.067 13.1 0.5 57 3.5 0.0 3.8 2 1 1 3 3 3 0 Esterase-like activity of phytase PRTP PF01366.18 GBG78263.1 - 0.95 7.4 5.9 1.7 6.6 5.9 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein zf-C2H2 PF00096.26 GBG78263.1 - 2.9 8.5 5.2 1.3 9.6 1.7 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.29 GBG78264.1 - 8e-40 136.5 0.0 1.4e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG78264.1 - 3.3e-30 104.7 0.1 4.8e-29 100.9 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG78264.1 - 4.4e-05 23.6 0.0 7.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG78264.1 - 0.019 14.3 0.3 0.072 12.4 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 GBG78264.1 - 0.061 13.7 0.1 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GBG78264.1 - 0.075 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 GBG78264.1 - 0.098 12.6 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Flavivirus DEAD domain FUSC-like PF12805.7 GBG78264.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DEAD PF00270.29 GBG78265.1 - 4.9e-39 133.9 0.0 8.3e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG78265.1 - 1.4e-28 99.5 0.1 4.4e-28 97.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Integrase_H2C2 PF17921.1 GBG78265.1 - 4.6e-18 65.1 0.9 9.6e-18 64.0 0.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78265.1 - 9e-12 45.2 0.0 3.2e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain cNMP_binding PF00027.29 GBG78265.1 - 0.047 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain zf-H2C2 PF09337.10 GBG78265.1 - 0.063 13.5 0.3 0.16 12.2 0.3 1.7 1 0 0 1 1 1 0 H2C2 zinc finger CMS1 PF14617.6 GBG78265.1 - 0.45 9.8 0.0 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 GBG78266.1 - 6.4e-40 136.8 0.0 1.1e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG78266.1 - 3.7e-30 104.5 0.1 4.6e-29 101.0 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG78266.1 - 6.4e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG78266.1 - 0.016 14.5 0.2 0.074 12.4 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 GBG78266.1 - 0.06 13.7 0.1 0.1 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 GBG78266.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain FUSC-like PF12805.7 GBG78266.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS RT_RNaseH PF17917.1 GBG78267.1 - 5.1e-24 84.6 0.0 1.1e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78267.1 - 8.1e-22 77.1 0.0 1.7e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78267.1 - 1e-18 67.2 1.6 2.4e-18 66.0 1.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78267.1 - 5.4e-18 65.3 0.0 1.8e-17 63.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG78267.1 - 0.023 14.9 0.2 0.045 14.0 0.2 1.5 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG78268.1 - 1.5e-06 28.0 3.0 4.7e-06 26.4 3.0 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG78268.1 - 0.007 16.0 1.9 0.016 14.9 1.9 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG78268.1 - 0.013 15.3 0.9 0.037 13.9 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF572 PF04502.13 GBG78268.1 - 0.5 9.9 20.0 0.82 9.2 20.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) MAT1 PF06391.13 GBG78268.1 - 1.9 8.2 17.2 1.8 8.3 15.4 1.8 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Sipho_Gp157 PF05565.11 GBG78269.1 - 0.42 10.6 4.9 0.52 10.3 4.9 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 FUSC PF04632.12 GBG78269.1 - 1.1 7.8 10.4 1.2 7.6 10.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C3HC4_4 PF15227.6 GBG78270.1 - 1.6e-11 44.1 0.5 4.1e-11 42.8 0.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GBG78270.1 - 9.6e-09 35.0 0.4 3.4e-08 33.2 0.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG78270.1 - 2.3e-08 33.9 2.5 6.4e-08 32.5 2.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.15 GBG78270.1 - 2.3e-08 34.1 0.0 7.1e-07 29.3 0.0 3.1 3 1 0 3 3 3 1 U-box domain zf-C3HC4_2 PF13923.6 GBG78270.1 - 1.8e-07 30.8 1.2 6.5e-07 29.1 1.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG78270.1 - 0.00011 22.0 2.0 0.00011 22.0 2.0 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG78270.1 - 0.00085 19.6 4.2 0.0034 17.7 4.2 2.2 1 0 0 1 1 1 1 Ring finger domain Arm PF00514.23 GBG78270.1 - 0.0059 16.6 11.8 3.4 7.8 0.0 8.1 9 1 1 10 10 10 1 Armadillo/beta-catenin-like repeat zf-RING_5 PF14634.6 GBG78270.1 - 0.038 14.0 0.4 0.17 11.9 0.4 2.1 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG78270.1 - 0.082 12.8 1.2 0.24 11.3 1.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GBG78270.1 - 0.1 12.9 3.0 0.43 10.9 3.0 2.2 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF3446 PF11928.8 GBG78270.1 - 4.3 7.7 9.9 12 6.3 9.9 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain Desulfoferrod_N PF06397.12 GBG78271.1 - 0.0041 16.7 2.4 0.29 10.8 0.1 2.4 2 0 0 2 2 2 2 Desulfoferrodoxin, N-terminal domain zf-BED PF02892.15 GBG78271.1 - 0.068 13.2 0.3 7.2 6.7 0.0 2.4 2 0 0 2 2 2 0 BED zinc finger RT_RNaseH_2 PF17919.1 GBG78272.1 - 2.8e-30 104.3 0.0 4.5e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78272.1 - 1.6e-25 89.4 0.0 2.7e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nicastrin PF05450.15 GBG78272.1 - 1.2e-14 54.3 0.0 2.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Nicastrin PF05450.15 GBG78273.1 - 6.2e-09 35.7 0.2 7.9e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 Nicastrin DnaJ PF00226.31 GBG78274.1 - 1.5e-22 79.5 0.4 2.5e-22 78.8 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain FKBP_C PF00254.28 GBG78274.1 - 1.1e-08 35.3 0.0 2.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SBD PF17882.1 GBG78274.1 - 0.015 15.1 0.1 0.038 13.8 0.0 1.7 2 0 0 2 2 2 0 OAA-family lectin sugar binding domain tRNA-synt_1c PF00749.21 GBG78275.1 - 5.3e-104 347.5 0.1 6.6e-104 347.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GBG78275.1 - 2.7e-35 121.8 0.0 4.4e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 GBG78275.1 - 1.6e-06 28.2 0.0 3.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GBG78275.1 - 9e-05 22.6 0.0 0.00031 20.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GBG78275.1 - 0.0046 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GBG78275.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 GBG78275.1 - 0.012 14.9 0.1 0.027 13.8 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Ribosomal_60s PF00428.19 GBG78276.1 - 2.2 8.9 7.8 0.1 13.2 1.7 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Histone PF00125.24 GBG78277.1 - 2.2e-12 47.5 0.3 4.7e-12 46.4 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RT_RNaseH_2 PF17919.1 GBG78279.1 - 2.4e-25 88.4 0.0 5e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78279.1 - 1.9e-20 73.1 0.0 3.5e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78279.1 - 2.4e-17 63.2 0.7 1.7e-13 50.6 0.2 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG78279.1 - 0.39 10.0 23.2 0.58 9.4 23.2 1.1 1 0 0 1 1 1 0 BUD22 CPSF100_C PF13299.6 GBG78279.1 - 1.3 9.2 6.1 2.4 8.3 6.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 GBG78279.1 - 6.7 4.8 22.7 9.3 4.3 22.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG78279.1 - 8.3 5.7 23.0 12 5.2 23.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG78279.1 - 9.5 4.4 17.1 14 3.9 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein ubiquitin PF00240.23 GBG78280.1 - 1.5e-07 31.1 0.3 3.8e-07 29.7 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 GBG78280.1 - 1.6e-05 25.3 0.1 7.1e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 GBG78280.1 - 0.0097 15.7 0.2 0.059 13.2 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 GBG78280.1 - 0.081 13.0 0.2 0.32 11.1 0.2 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain SufE PF02657.15 GBG78281.1 - 1.5e-37 128.1 0.0 2.2e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.18 GBG78281.1 - 9.7e-29 99.5 0.2 1.6e-28 98.8 0.2 1.4 1 0 0 1 1 1 1 BolA-like protein Axin_b-cat_bind PF08833.10 GBG78281.1 - 0.1 12.7 0.5 24 5.2 0.0 3.3 3 0 0 3 3 3 0 Axin beta-catenin binding domain MarR_2 PF12802.7 GBG78282.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 MarR family DUF4150 PF13665.6 GBG78282.1 - 0.072 13.3 0.4 0.63 10.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) HTH_IclR PF09339.10 GBG78282.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain DNA_pol_B_exo1 PF03104.19 GBG78283.1 - 1.9e-07 30.6 0.0 1.4e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 GBG78284.1 - 4.4e-98 329.0 0.0 5.3e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 GBG78284.1 - 6e-13 49.0 0.8 1.1e-12 48.2 0.8 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta GRP PF07172.11 GBG78285.1 - 0.11 13.2 22.8 0.16 12.7 22.8 1.3 1 0 0 1 1 1 0 Glycine rich protein family Pex19 PF04614.12 GBG78286.1 - 0.26 11.0 19.1 0.36 10.6 19.1 1.2 1 0 0 1 1 1 0 Pex19 protein family Prominin PF05478.11 GBG78286.1 - 2.8 5.8 5.7 3.3 5.5 5.7 1.0 1 0 0 1 1 1 0 Prominin N36 PF11438.8 GBG78286.1 - 8.9 6.2 10.1 7.7 6.4 1.1 2.8 2 0 0 2 2 2 0 36-mer N-terminal peptide of the N protein (N36) TMEM192 PF14802.6 GBG78287.1 - 0.00018 20.7 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 TMEM192 family TMCO5 PF14992.6 GBG78287.1 - 0.018 14.6 0.1 0.024 14.2 0.1 1.1 1 0 0 1 1 1 0 TMCO5 family Fez1 PF06818.15 GBG78287.1 - 0.044 14.2 4.0 0.057 13.9 4.0 1.2 1 0 0 1 1 1 0 Fez1 RGCC PF15151.6 GBG78287.1 - 0.06 13.6 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Response gene to complement 32 protein family Phage_GP20 PF06810.11 GBG78287.1 - 0.22 11.3 0.9 1.5 8.6 0.2 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 SlyX PF04102.12 GBG78287.1 - 4.5 8.0 8.4 1.5 9.5 0.8 3.5 3 1 2 5 5 5 0 SlyX TMEM192 PF14802.6 GBG78288.1 - 7.6e-09 35.0 0.0 1.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 TMEM192 family TMCO5 PF14992.6 GBG78288.1 - 0.016 14.8 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 TMCO5 family Fez1 PF06818.15 GBG78288.1 - 0.058 13.9 4.5 0.073 13.5 4.5 1.2 1 0 0 1 1 1 0 Fez1 RGCC PF15151.6 GBG78288.1 - 0.058 13.6 0.3 0.097 12.9 0.3 1.3 1 0 0 1 1 1 0 Response gene to complement 32 protein family Phage_GP20 PF06810.11 GBG78288.1 - 0.19 11.5 0.9 1.4 8.7 0.2 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Pkinase PF00069.25 GBG78289.1 - 1.8e-35 122.6 0.0 2.8e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG78289.1 - 5.1e-33 114.5 0.0 1.2e-32 113.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 GBG78289.1 - 1.3e-14 52.5 7.7 5e-05 22.7 0.3 3.7 3 0 0 3 3 3 3 IQ calmodulin-binding motif TMEM154 PF15102.6 GBG78289.1 - 0.00013 21.9 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family APH PF01636.23 GBG78289.1 - 0.012 15.6 1.2 0.021 14.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family SGL PF08450.12 GBG78289.1 - 0.07 12.7 0.0 0.8 9.2 0.0 2.5 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Insulin_TMD PF17870.1 GBG78289.1 - 0.27 11.4 3.2 0.12 12.5 0.2 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Trypan_PARP PF05887.11 GBG78289.1 - 7.6 6.5 30.2 10 6.1 5.1 2.9 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) RVT_1 PF00078.27 GBG78290.1 - 3.5e-09 36.5 0.0 5.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG78290.1 - 1.2 8.5 18.0 1.8 7.9 18.0 1.2 1 0 0 1 1 1 0 SDA1 DDRGK PF09756.9 GBG78290.1 - 3 7.4 20.3 4.7 6.8 20.3 1.2 1 0 0 1 1 1 0 DDRGK domain DUF4746 PF15928.5 GBG78290.1 - 6.8 6.0 8.9 10 5.4 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Integrase_H2C2 PF17921.1 GBG78291.1 - 2.1e-15 56.5 0.1 5.2e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF659 PF04937.15 GBG78291.1 - 6.5e-14 52.1 0.1 1.4e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG78291.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78291.1 - 0.084 13.1 0.2 44 4.3 0.0 3.4 3 0 0 3 3 3 0 Integrase core domain Myb_DNA-bind_4 PF13837.6 GBG78292.1 - 4.2e-07 30.2 3.1 4.2e-07 30.2 3.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG78292.1 - 0.017 15.4 2.7 0.049 14.0 0.8 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG78292.1 - 0.029 14.4 0.5 0.066 13.3 0.5 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF627 PF04781.12 GBG78292.1 - 0.1 12.6 0.3 0.18 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) bZIP_1 PF00170.21 GBG78292.1 - 0.11 12.7 0.2 0.23 11.6 0.1 1.6 1 1 0 1 1 1 0 bZIP transcription factor Myb_DNA-binding PF00249.31 GBG78292.1 - 0.14 12.4 0.7 0.35 11.1 0.7 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2344 PF10105.9 GBG78293.1 - 1.1e-39 136.0 0.0 2.2e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) DDE_Tnp_4 PF13359.6 GBG78293.1 - 4.6e-31 107.6 0.0 7.9e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Radical_SAM PF04055.21 GBG78293.1 - 5.7e-16 59.3 0.0 4.3e-15 56.5 0.0 2.4 2 0 0 2 2 2 1 Radical SAM superfamily Plant_tran PF04827.14 GBG78293.1 - 3.1e-14 53.1 0.0 7.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG78293.1 - 0.00089 19.0 0.1 1.7 8.3 0.0 2.6 2 0 0 2 2 2 2 Transposase DDE domain Radial_spoke PF04712.12 GBG78293.1 - 0.29 10.0 1.3 0.42 9.5 1.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Dscam_C PF12355.8 GBG78293.1 - 2.1 9.3 7.5 3.5 8.6 1.3 2.5 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal NAD_binding_8 PF13450.6 GBG78294.1 - 2.9e-14 53.0 0.5 9.1e-14 51.4 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GBG78294.1 - 0.00022 20.6 0.0 0.002 17.5 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 GBG78294.1 - 0.0043 16.3 0.8 0.0067 15.7 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GBG78294.1 - 0.0069 15.1 0.1 0.0096 14.7 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GBG78294.1 - 0.01 15.1 0.1 0.015 14.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG78294.1 - 0.069 13.7 0.4 0.13 12.9 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GBG78294.1 - 0.27 10.3 0.7 0.37 9.8 0.7 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A SMP PF04927.12 GBG78295.1 - 8e-25 87.1 5.6 1.9e-12 47.5 1.3 2.8 2 1 1 3 3 3 2 Seed maturation protein Peptidase_A22B PF04258.13 GBG78297.1 - 4.4e-73 246.3 6.9 6.3e-73 245.8 6.9 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF3671 PF12420.8 GBG78297.1 - 0.085 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function mTERF PF02536.14 GBG78298.1 - 5.5e-110 367.2 0.0 3e-68 230.1 0.0 3.2 2 1 1 3 3 3 3 mTERF PRIMA1 PF16101.5 GBG78298.1 - 0.34 11.0 21.7 2.4 8.2 5.5 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG78298.1 - 3.9 6.9 21.1 1.8 7.9 5.8 2.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal RRF PF01765.19 GBG78300.1 - 1.1e-36 126.2 0.2 3e-36 124.8 0.0 1.7 1 1 1 2 2 2 1 Ribosome recycling factor Diphthamide_syn PF01866.17 GBG78301.1 - 2.2e-77 260.5 0.0 6.6e-76 255.7 0.0 2.6 2 1 0 2 2 2 1 Putative diphthamide synthesis protein DUF5567 PF17722.1 GBG78302.1 - 0.035 14.0 0.3 0.046 13.6 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5567) Suv3_N PF18114.1 GBG78302.1 - 0.075 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Suv3 helical N-terminal domain QRPTase_C PF01729.19 GBG78303.1 - 0.19 11.5 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF659 PF04937.15 GBG78304.1 - 6.5e-14 52.1 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Presenilin PF01080.17 GBG78305.1 - 0.016 14.0 4.9 0.019 13.7 4.9 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.19 GBG78305.1 - 0.055 14.1 8.9 0.055 14.1 8.9 4.1 2 1 1 3 3 3 0 60s Acidic ribosomal protein SAPS PF04499.15 GBG78305.1 - 0.32 9.7 10.3 0.34 9.7 10.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 GBG78305.1 - 0.44 9.5 1.9 0.5 9.3 1.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Nop25 PF09805.9 GBG78305.1 - 5.3 7.5 35.9 0.17 12.4 20.1 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) SWIB PF02201.18 GBG78306.1 - 9.4e-57 188.8 1.2 2.8e-27 94.4 0.1 2.4 2 0 0 2 2 2 2 SWIB/MDM2 domain DEK_C PF08766.11 GBG78306.1 - 1.3e-11 44.3 0.6 3.4e-11 42.9 0.6 1.8 1 0 0 1 1 1 1 DEK C terminal domain CDC45 PF02724.14 GBG78306.1 - 0.023 13.0 0.2 0.027 12.8 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG78306.1 - 0.029 12.5 9.5 0.043 11.9 9.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF3295 PF11702.8 GBG78306.1 - 0.089 12.1 3.7 0.13 11.6 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Nop14 PF04147.12 GBG78306.1 - 0.38 8.9 10.0 0.51 8.5 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG78306.1 - 0.75 9.1 11.7 1.2 8.4 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein Nop25 PF09805.9 GBG78306.1 - 3 8.3 10.3 8.1 6.9 10.3 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Roughex PF06020.11 GBG78306.1 - 9.9 5.1 7.8 14 4.6 7.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Ribosomal_L27A PF00828.19 GBG78307.1 - 1e-22 81.2 0.2 1.4e-22 80.7 0.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 GBG78307.1 - 0.083 13.0 1.9 0.3 11.2 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5026) PhoLip_ATPase_C PF16212.5 GBG78308.1 - 3.6e-67 226.7 17.4 4.5e-67 226.4 17.4 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 GBG78308.1 - 1.8e-09 38.2 0.3 1.2e-06 29.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Fe_hyd_lg_C PF02906.14 GBG78309.1 - 6.5e-94 314.2 0.0 1e-93 313.5 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 GBG78309.1 - 6e-24 83.9 2.4 1.1e-23 83.0 2.4 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer2_4 PF13510.6 GBG78309.1 - 1.7e-17 63.2 0.6 5.1e-17 61.7 0.1 2.2 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 GBG78309.1 - 2.4e-08 33.5 11.3 0.00019 21.1 2.3 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain NADH-G_4Fe-4S_3 PF10588.9 GBG78309.1 - 3.3e-08 32.9 0.1 3.3e-08 32.9 0.1 2.3 3 0 0 3 3 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4_21 PF14697.6 GBG78309.1 - 7.7e-08 32.3 4.6 2.7e-07 30.6 4.6 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 GBG78309.1 - 8e-06 25.9 5.7 8e-06 25.9 5.7 3.0 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 GBG78309.1 - 9.9e-06 25.6 9.6 0.0069 16.5 0.4 3.3 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 GBG78309.1 - 6.8e-05 23.7 7.7 0.00018 22.4 0.2 3.3 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 GBG78309.1 - 0.0001 22.8 14.2 0.00015 22.3 10.5 3.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 GBG78309.1 - 0.00014 22.3 12.4 0.0003 21.2 8.6 2.9 1 1 3 4 4 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 GBG78309.1 - 0.0012 18.8 19.5 0.012 15.7 2.9 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 GBG78309.1 - 0.0027 18.2 10.1 0.14 12.7 0.3 3.0 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 GBG78309.1 - 0.0057 17.4 4.8 2 9.2 0.1 3.2 3 0 0 3 3 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.6 GBG78309.1 - 0.028 14.6 6.4 1.9 8.7 0.7 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 GBG78309.1 - 0.16 12.8 0.3 0.16 12.8 0.3 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain RseC_MucC PF04246.12 GBG78309.1 - 0.23 11.4 2.8 0.73 9.8 0.0 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Fer4_4 PF12800.7 GBG78309.1 - 0.3 11.7 20.1 0.038 14.5 2.8 3.4 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 GBG78309.1 - 1.1 9.9 8.6 12 6.6 2.6 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I CDK2AP PF09806.9 GBG78309.1 - 3.8 7.5 12.0 6.7 6.7 3.5 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein RT_RNaseH_2 PF17919.1 GBG78310.1 - 3.7e-29 100.7 0.0 6.9e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78310.1 - 1e-28 99.7 0.0 2.1e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PhoLip_ATPase_N PF16209.5 GBG78310.1 - 1.1e-18 66.6 0.0 2.9e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 GBG78310.1 - 3.6e-06 26.6 0.2 0.00053 19.6 0.0 2.4 2 0 0 2 2 2 2 E1-E2 ATPase Phage_GPO PF05929.11 GBG78310.1 - 0.086 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG78311.1 - 3.6e-29 100.7 0.0 6.7e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78311.1 - 9.8e-29 99.7 0.0 2.1e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PhoLip_ATPase_N PF16209.5 GBG78311.1 - 1.1e-18 66.7 0.0 2.8e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Phage_GPO PF05929.11 GBG78311.1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SRP72 PF08492.12 GBG78312.1 - 1.4e-14 54.3 8.6 1.4e-14 54.3 8.6 2.6 2 1 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.6 GBG78312.1 - 1.1e-07 32.0 9.8 0.0021 18.3 0.1 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG78312.1 - 2e-07 31.4 17.3 0.27 11.7 0.7 7.7 4 2 3 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG78312.1 - 4.8e-06 26.7 5.1 0.0055 16.9 0.1 5.0 4 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GBG78312.1 - 1.8e-05 25.1 16.5 3.6 8.6 0.0 8.7 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG78312.1 - 3.6e-05 23.5 13.2 7.4 6.9 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 GBG78312.1 - 8.2e-05 22.6 0.9 0.064 13.3 0.0 3.3 2 2 0 3 3 3 2 Putative TPR-like repeat TPR_16 PF13432.6 GBG78312.1 - 9.6e-05 22.9 25.2 0.93 10.2 0.0 7.9 8 1 0 8 8 7 3 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 GBG78312.1 - 0.00032 20.3 4.9 0.0045 16.6 0.8 3.7 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 GBG78312.1 - 0.087 12.7 7.7 1.1 9.2 0.3 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG78312.1 - 0.42 11.4 18.2 6.1 7.7 0.0 7.3 9 0 0 9 9 8 0 Tetratricopeptide repeat HEAT_2 PF13646.6 GBG78312.1 - 1.4 9.4 5.4 0.98 9.9 0.1 3.2 2 1 1 3 3 3 0 HEAT repeats TPR_3 PF07720.12 GBG78312.1 - 1.8 8.6 5.8 13 5.9 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 GBG78313.1 - 4.7e-07 29.6 8.0 7.9e-07 28.8 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG78313.1 - 4e-05 23.5 12.5 7.5e-05 22.6 12.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG78313.1 - 4.4e-05 23.3 12.7 7.8e-05 22.5 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG78313.1 - 0.00014 21.6 11.4 0.00022 21.0 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG78313.1 - 0.00031 21.0 11.1 0.00052 20.3 11.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 GBG78313.1 - 0.0013 18.8 5.4 0.0025 17.9 5.4 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 GBG78313.1 - 0.0043 17.1 10.9 0.0092 16.0 10.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GBG78313.1 - 0.02 14.7 9.8 0.041 13.7 9.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 YebO PF13974.6 GBG78313.1 - 0.12 12.5 0.1 0.12 12.5 0.1 3.1 3 0 0 3 3 3 0 YebO-like protein Roughex PF06020.11 GBG78313.1 - 0.14 11.2 11.3 0.041 13.0 7.3 2.1 2 0 0 2 2 2 0 Drosophila roughex protein zf-C3HC4_4 PF15227.6 GBG78313.1 - 0.22 11.7 9.5 0.44 10.8 9.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 GBG78313.1 - 0.23 11.2 7.8 0.53 10.0 7.8 1.6 1 1 0 1 1 1 0 P-11 zinc finger DUF2256 PF10013.9 GBG78313.1 - 0.58 10.3 4.6 2.7 8.2 0.2 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Nse PF11789.8 GBG78313.1 - 1.5 8.7 5.5 3 7.7 5.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 GBG78313.1 - 2.6 8.4 10.5 9.9 6.5 10.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Spt20 PF12090.8 GBG78313.1 - 5.9 6.4 9.2 12 5.4 9.2 1.4 1 0 0 1 1 1 0 Spt20 family Lactamase_B_2 PF12706.7 GBG78314.1 - 1.5e-24 86.6 0.1 4.3e-24 85.2 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GBG78314.1 - 1.8e-06 28.1 1.5 5.6e-06 26.5 1.3 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Peptidase_C48 PF02902.19 GBG78317.1 - 3.5e-12 46.6 0.1 7.3e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Bud13 PF09736.9 GBG78318.1 - 7.7e-38 130.2 2.4 7.7e-38 130.2 2.4 2.9 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Zip PF02535.22 GBG78319.1 - 0.24 10.6 4.6 0.23 10.6 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF948 PF06103.11 GBG78319.1 - 0.36 11.1 2.8 0.51 10.6 0.2 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Dsh_C PF12316.8 GBG78319.1 - 7.8 6.9 13.3 14 6.0 13.3 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SLT_2 PF13406.6 GBG78320.1 - 1.8e-70 237.5 0.7 1e-62 212.0 0.3 2.2 1 1 1 2 2 2 2 Transglycosylase SLT domain HEAT PF02985.22 GBG78321.1 - 4.4e-40 132.3 26.5 0.00083 19.4 0.0 12.8 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.6 GBG78321.1 - 6.9e-37 125.7 2.6 4.6e-12 46.2 0.0 7.3 3 3 5 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.7 GBG78321.1 - 4.8e-11 43.1 2.1 0.027 15.1 0.0 7.0 3 3 4 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GBG78321.1 - 1.4e-10 41.4 9.0 0.013 15.5 0.1 5.3 4 2 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 GBG78321.1 - 1.5e-08 34.8 1.0 0.91 9.7 0.0 4.7 4 2 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 GBG78321.1 - 1.2e-06 28.9 8.8 0.0082 16.6 0.0 6.4 7 1 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.8 GBG78321.1 - 0.00011 21.8 0.0 0.41 10.2 0.0 3.3 3 1 0 3 3 3 2 CLASP N terminal Adaptin_N PF01602.20 GBG78321.1 - 0.00068 18.3 2.6 0.8 8.2 0.1 4.0 1 1 2 3 3 3 3 Adaptin N terminal region HEAT_PBS PF03130.16 GBG78321.1 - 0.0066 17.0 0.4 13 6.8 0.0 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat DUF3389 PF11869.8 GBG78321.1 - 0.16 12.2 0.1 2.7 8.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3389) HEAT PF02985.22 GBG78322.1 - 4.4e-40 132.3 26.7 0.00081 19.4 0.0 12.8 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.6 GBG78322.1 - 5.5e-37 126.0 2.4 4.5e-12 46.2 0.0 7.3 3 3 5 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.7 GBG78322.1 - 4.4e-11 43.2 1.9 0.027 15.0 0.0 6.9 3 3 4 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GBG78322.1 - 9.4e-11 42.0 8.8 0.013 15.6 0.1 5.3 4 2 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 GBG78322.1 - 1.4e-08 34.9 1.0 0.89 9.8 0.0 4.7 4 1 1 5 5 5 4 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 GBG78322.1 - 3.5e-07 30.6 7.2 0.008 16.7 0.0 6.4 7 1 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.8 GBG78322.1 - 0.00014 21.5 0.0 0.52 9.8 0.0 3.3 3 1 0 3 3 3 2 CLASP N terminal Adaptin_N PF01602.20 GBG78322.1 - 0.00043 19.0 2.1 0.83 8.1 0.1 4.0 1 1 2 3 3 3 3 Adaptin N terminal region HEAT_PBS PF03130.16 GBG78322.1 - 0.0053 17.3 0.2 13 6.8 0.0 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat DUF3389 PF11869.8 GBG78322.1 - 0.19 11.9 0.4 2.7 8.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3389) FlaC_arch PF05377.11 GBG78324.1 - 0.048 14.1 0.7 0.099 13.1 0.7 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Mpp10 PF04006.12 GBG78325.1 - 2.8e-15 55.8 85.5 2.3e-14 52.8 18.1 2.8 1 1 1 2 2 2 2 Mpp10 protein DUF2201_N PF13203.6 GBG78325.1 - 0.033 13.8 0.1 0.033 13.8 0.1 3.1 1 1 2 3 3 3 0 Putative metallopeptidase domain PilZ_2 PF16823.5 GBG78325.1 - 1.2 9.3 0.0 1.2 9.3 0.0 3.1 3 1 0 3 3 3 0 Atypical PilZ domain, cyclic di-GMP receptor Mpp10 PF04006.12 GBG78326.1 - 2.2e-83 280.8 8.5 2.6e-83 280.5 8.5 1.0 1 0 0 1 1 1 1 Mpp10 protein FAA_hydrolase PF01557.18 GBG78327.1 - 4.1e-60 203.2 0.0 4.8e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family OCD_Mu_crystall PF02423.15 GBG78327.1 - 0.0056 15.7 0.2 0.011 14.6 0.0 1.5 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Thioredoxin PF00085.20 GBG78328.1 - 4.6e-23 81.2 0.0 5.7e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GBG78328.1 - 1.2e-06 28.7 0.0 7.3e-05 23.0 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GBG78328.1 - 9.3e-06 25.7 0.0 3.1e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GBG78328.1 - 2.2e-05 24.2 0.1 2.6e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG78328.1 - 0.00017 22.0 0.0 0.00082 19.8 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GBG78328.1 - 0.0027 17.1 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 GBG78328.1 - 0.0057 16.6 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family KaiB PF07689.12 GBG78328.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiB domain Thioredoxin PF00085.20 GBG78329.1 - 1.8e-24 85.7 0.0 2.2e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GBG78329.1 - 1.1e-07 32.0 0.3 7.4e-05 23.0 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 GBG78329.1 - 3.4e-07 30.1 0.0 3.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GBG78329.1 - 9e-07 28.5 0.0 9.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GBG78329.1 - 9e-07 29.0 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GBG78329.1 - 1.3e-06 28.8 0.0 4.6e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GBG78329.1 - 0.0014 18.6 0.1 0.0023 17.8 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GBG78329.1 - 0.014 15.1 0.1 0.029 14.1 0.1 1.4 1 1 0 1 1 1 0 Redoxin TraF PF13728.6 GBG78329.1 - 0.055 13.3 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein MDD_C PF18376.1 GBG78330.1 - 2.2e-69 232.9 0.0 3.8e-69 232.2 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 GBG78330.1 - 2.1e-08 34.2 6.5 3.2e-08 33.7 3.5 2.6 2 0 0 2 2 2 1 GHMP kinases N terminal domain DNA_pol_A_exo1 PF01612.20 GBG78331.1 - 6e-16 58.6 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease SDA1 PF05285.12 GBG78332.1 - 0.028 13.8 17.5 0.026 14.0 17.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG78332.1 - 0.19 9.9 16.3 0.16 10.2 16.3 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 GBG78332.1 - 0.36 10.2 12.9 0.42 10.0 12.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 GBG78332.1 - 0.45 8.9 16.2 0.37 9.2 16.2 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 GBG78332.1 - 1.3 8.3 14.2 1.1 8.5 14.2 1.1 1 0 0 1 1 1 0 BUD22 DUF2076 PF09849.9 GBG78332.1 - 4.7 7.2 13.1 5 7.1 13.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) YL1 PF05764.13 GBG78332.1 - 9.8 6.2 23.9 12 6.0 23.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DDE_Tnp_4 PF13359.6 GBG78333.1 - 5.7e-28 97.6 0.0 9.7e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78333.1 - 5.2e-14 52.3 0.0 8e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG78333.1 - 0.004 16.8 0.4 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Transposase DDE domain CN_hydrolase PF00795.22 GBG78334.1 - 1.5e-56 191.6 0.0 2e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Exotox-A_cataly PF09009.10 GBG78334.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Exotoxin A catalytic MVL PF12151.8 GBG78335.1 - 0.099 12.5 0.8 0.6 10.0 0.1 2.4 2 0 0 2 2 2 0 Mannan-binding protein RVT_1 PF00078.27 GBG78336.1 - 2e-21 76.6 0.1 3.2e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG78336.1 - 0.082 12.7 0.2 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG78339.1 - 9.2e-07 29.2 0.3 1.7e-06 28.3 0.2 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG78339.1 - 0.0019 18.2 0.5 0.0038 17.3 0.1 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain GP40 PF11025.8 GBG78339.1 - 3.1 7.5 7.6 0.28 10.9 0.5 2.3 1 1 1 2 2 2 0 Glycoprotein GP40 of Cryptosporidium CDC48_N PF02359.18 GBG78342.1 - 1.4 9.2 9.3 9.4 6.5 0.7 3.8 3 1 1 4 4 4 0 Cell division protein 48 (CDC48), N-terminal domain KorB_C PF06613.11 GBG78343.1 - 2.8 8.0 4.8 0.84 9.7 0.3 2.2 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain RVT_1 PF00078.27 GBG78347.1 - 1.9e-36 125.7 0.0 3.3e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG78347.1 - 0.001 19.7 0.0 0.0025 18.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG78347.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG78347.1 - 0.0015 19.1 0.0 0.0038 17.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG78347.1 - 0.066 13.0 0.0 0.52 10.1 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG78348.1 - 3.8e-22 78.2 0.0 7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78348.1 - 3e-15 56.3 0.1 2.4e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78348.1 - 3.9e-13 49.6 0.0 7.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Occludin_ELL PF07303.13 GBG78348.1 - 0.058 14.1 0.9 0.17 12.6 0.9 1.7 1 0 0 1 1 1 0 Occludin homology domain Myb_DNA-bind_4 PF13837.6 GBG78351.1 - 5.3e-05 23.5 1.4 0.0002 21.7 1.4 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF2207 PF09972.9 GBG78351.1 - 1.5 7.4 6.5 2.9 6.5 6.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Nop14 PF04147.12 GBG78353.1 - 0.007 14.7 35.0 0.0075 14.6 35.0 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 GBG78353.1 - 0.016 13.5 28.5 0.019 13.3 28.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GBG78353.1 - 0.045 12.2 35.9 0.05 12.1 35.9 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG78353.1 - 0.15 11.4 39.9 0.18 11.2 39.9 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG78353.1 - 0.55 9.5 39.3 0.58 9.4 39.3 1.0 1 0 0 1 1 1 0 BUD22 Merozoite_SPAM PF07133.11 GBG78353.1 - 0.93 9.5 55.0 1.5 8.7 55.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2151 PF10221.9 GBG78353.1 - 2.9 6.4 13.7 2.8 6.4 13.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 GBG78353.1 - 3.9 6.6 12.0 4.3 6.5 12.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 GBG78353.1 - 4.8 6.9 29.0 7.7 6.3 29.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 GBG78353.1 - 5.6 6.4 22.6 6.8 6.2 22.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 GBG78353.1 - 5.8 5.8 13.2 5.9 5.8 13.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 GBG78353.1 - 8.7 4.8 15.2 10 4.5 15.2 1.0 1 0 0 1 1 1 0 Macoilin family NOA36 PF06524.12 GBG78354.1 - 0.15 11.3 4.4 0.16 11.2 4.4 1.1 1 0 0 1 1 1 0 NOA36 protein Connexin PF00029.19 GBG78354.1 - 2.4 7.8 3.2 2.4 7.8 3.2 1.0 1 0 0 1 1 1 0 Connexin zf-TAZ PF02135.16 GBG78355.1 - 2.6 8.6 18.1 0.057 13.9 9.9 2.4 2 0 0 2 2 2 0 TAZ zinc finger DUF2052 PF09747.9 GBG78355.1 - 3.6 7.7 15.1 1 9.5 1.5 3.5 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Oleosin PF01277.17 GBG78356.1 - 1.9e-14 53.4 6.0 3e-14 52.7 6.0 1.3 1 0 0 1 1 1 1 Oleosin OpgC_C PF10129.9 GBG78356.1 - 0.13 11.1 5.5 0.15 10.9 5.5 1.1 1 0 0 1 1 1 0 OpgC protein DUF3318 PF11780.8 GBG78356.1 - 4.2 7.3 6.8 2.6 8.0 3.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3318) Phage_holin_3_6 PF07332.11 GBG78356.1 - 5.6 7.0 18.4 44 4.2 18.4 2.1 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RVT_1 PF00078.27 GBG78357.1 - 2.4e-29 102.5 0.1 4.1e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG78357.1 - 0.19 12.4 0.0 0.41 11.3 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Sel1 PF08238.12 GBG78360.1 - 1.6e-55 184.3 34.9 7.9e-10 39.1 0.4 9.5 10 0 0 10 10 10 8 Sel1 repeat TPR_11 PF13414.6 GBG78360.1 - 0.0021 17.7 1.1 0.68 9.7 0.1 3.9 4 0 0 4 4 4 1 TPR repeat TPR_16 PF13432.6 GBG78360.1 - 0.0082 16.8 13.3 2.1 9.1 1.6 5.2 3 1 2 5 5 5 4 Tetratricopeptide repeat Oleosin PF01277.17 GBG78361.1 - 1.6e-05 24.7 9.2 1.6e-05 24.7 9.2 2.3 2 1 0 2 2 2 1 Oleosin NTP_transferase PF00483.23 GBG78363.1 - 9.7e-51 172.7 0.0 1.7e-50 171.9 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 GBG78363.1 - 1e-10 42.2 0.0 1.3e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 GBG78363.1 - 2.3e-09 36.6 4.9 9.6e-06 25.1 0.7 3.4 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 GBG78363.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 GBG78363.1 - 0.038 13.9 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.12 GBG78363.1 - 0.11 11.4 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 GBG78363.1 - 0.11 10.6 0.1 0.16 10.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 GBG78363.1 - 0.4 10.5 2.6 2.1 8.2 1.0 3.1 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Amino_oxidase PF01593.24 GBG78364.1 - 2.2e-56 192.1 0.3 4e-41 141.7 0.0 3.0 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG78364.1 - 2.3e-09 37.3 0.0 5.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG78364.1 - 1.5e-05 24.7 1.5 4.4e-05 23.2 0.7 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GBG78364.1 - 2e-05 24.0 0.1 3.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 GBG78364.1 - 3.6e-05 23.0 0.8 0.00023 20.3 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GBG78364.1 - 3.7e-05 23.1 0.0 8.3e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG78364.1 - 7.8e-05 23.2 0.7 0.0005 20.6 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GBG78364.1 - 0.00027 20.1 0.4 0.00056 19.1 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GBG78364.1 - 0.00061 19.3 2.6 0.011 15.2 0.7 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GBG78364.1 - 0.0011 18.2 0.1 0.0026 16.9 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GBG78364.1 - 0.0026 17.1 0.1 0.0051 16.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GBG78364.1 - 0.0034 16.1 0.1 0.0091 14.7 0.1 1.7 1 0 0 1 1 1 1 HI0933-like protein Mqo PF06039.15 GBG78364.1 - 0.0081 14.8 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 GBG78364.1 - 0.18 11.8 2.3 0.34 10.9 0.2 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Myb_DNA-bind_4 PF13837.6 GBG78365.1 - 2.4e-06 27.8 5.0 7.6e-06 26.2 3.0 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG78365.1 - 0.043 14.1 2.2 0.1 12.9 0.7 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG78365.1 - 0.047 13.9 0.8 0.096 13.0 0.8 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG78365.1 - 0.3 11.2 3.8 0.097 12.8 1.0 1.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG78367.1 - 1.5e-23 83.2 0.0 5.7e-23 81.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78367.1 - 2e-12 47.2 0.0 3.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG78367.1 - 0.0079 15.9 0.3 0.028 14.0 0.0 2.0 2 0 0 2 2 2 1 Transposase DDE domain SNAD2 PF18745.1 GBG78368.1 - 0.12 12.1 9.0 0.059 13.1 2.0 2.5 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 2 HALZ PF02183.18 GBG78368.1 - 7.7 6.8 27.1 14 6.0 0.0 6.0 5 1 0 5 5 5 0 Homeobox associated leucine zipper Oleosin PF01277.17 GBG78369.1 - 9.5e-09 35.0 8.1 1.6e-08 34.3 8.1 1.3 1 0 0 1 1 1 1 Oleosin 60KD_IMP PF02096.20 GBG78370.1 - 0.0012 18.8 9.4 0.0019 18.1 9.4 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2457 PF10446.9 GBG78370.1 - 0.003 16.8 5.8 0.003 16.8 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GBG78370.1 - 0.0037 15.5 1.5 0.0037 15.5 1.5 1.2 1 0 0 1 1 1 1 DNA polymerase phi CENP-B_dimeris PF09026.10 GBG78370.1 - 0.0076 16.6 10.1 0.0076 16.6 10.1 1.6 2 0 0 2 2 2 1 Centromere protein B dimerisation domain AJAP1_PANP_C PF15298.6 GBG78370.1 - 0.033 14.4 2.1 0.041 14.1 2.1 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus GCIP PF13324.6 GBG78370.1 - 0.039 13.5 5.5 0.048 13.3 5.5 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF3439 PF11921.8 GBG78370.1 - 0.1 12.5 11.7 0.14 12.1 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sigma70_ner PF04546.13 GBG78370.1 - 0.12 12.3 0.5 0.12 12.3 0.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region TFIIF_alpha PF05793.12 GBG78370.1 - 0.12 10.9 3.9 0.13 10.8 3.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp14 PF04615.13 GBG78370.1 - 0.14 10.7 0.6 0.14 10.7 0.6 1.0 1 0 0 1 1 1 0 Utp14 protein NDUF_B8 PF05821.11 GBG78370.1 - 0.2 11.5 8.9 0.24 11.2 8.9 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Sporozoite_P67 PF05642.11 GBG78370.1 - 0.5 8.4 2.0 0.6 8.1 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 GBG78370.1 - 2.3 6.7 5.4 2.7 6.4 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Orf78 PF06024.12 GBG78370.1 - 9.9 6.5 6.9 19 5.6 6.9 1.5 1 1 0 1 1 1 0 Orf78 (ac78) Sel1 PF08238.12 GBG78371.1 - 1e-88 289.7 33.9 7.2e-12 45.6 0.2 9.0 9 0 0 9 9 9 9 Sel1 repeat TPR_16 PF13432.6 GBG78371.1 - 0.00074 20.1 13.8 0.15 12.8 1.6 4.9 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG78371.1 - 0.0057 17.2 17.2 12 6.7 0.1 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat Flu_M1_C PF08289.11 GBG78371.1 - 0.051 13.8 0.2 26 5.1 0.1 3.4 3 0 0 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain YcbB PF08664.10 GBG78371.1 - 0.086 12.9 0.0 6.9 6.7 0.1 3.0 3 0 0 3 3 3 0 YcbB domain TMEM190 PF15431.6 GBG78371.1 - 0.6 10.3 2.4 32 4.7 0.0 3.4 3 1 1 4 4 4 0 Transmembrane protein 190 TPR_1 PF00515.28 GBG78371.1 - 2 8.4 29.0 15 5.6 0.0 9.5 11 0 0 11 11 11 0 Tetratricopeptide repeat RRM_1 PF00076.22 GBG78372.1 - 4.4e-15 55.3 0.0 7.8e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 GBG78372.1 - 6.5e-12 45.3 2.3 1.4e-11 44.2 2.3 1.6 1 0 0 1 1 1 1 WW domain HALZ PF02183.18 GBG78372.1 - 0.31 11.3 8.7 4 7.7 0.4 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper betaPIX_CC PF16523.5 GBG78372.1 - 0.61 10.0 14.8 0.86 9.5 1.3 3.3 2 1 1 3 3 3 0 betaPIX coiled coil LURAP PF14854.6 GBG78372.1 - 2.1 8.3 5.6 0.49 10.3 1.1 2.2 2 0 0 2 2 2 0 Leucine rich adaptor protein IF-2B PF01008.17 GBG78372.1 - 2.1 7.5 5.2 3.7 6.7 5.2 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family CENP-F_leu_zip PF10473.9 GBG78372.1 - 3.4 7.7 33.4 16 5.5 9.1 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Arm-DNA-bind_5 PF17293.2 GBG78373.1 - 0.19 12.2 2.2 4.3 7.8 2.1 2.6 1 1 1 2 2 2 0 Arm DNA-binding domain CDC45 PF02724.14 GBG78374.1 - 0.0016 16.8 9.3 0.0022 16.4 9.3 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG78374.1 - 0.0047 15.2 13.5 0.0074 14.6 13.5 1.2 1 0 0 1 1 1 1 Nop14-like family WD40 PF00400.32 GBG78376.1 - 4.2e-21 74.8 0.3 2.5e-07 31.2 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG78376.1 - 0.023 15.0 0.1 3.3 8.1 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG78376.1 - 0.06 12.7 0.1 9.5 5.4 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain RVT_1 PF00078.27 GBG78377.1 - 9.4e-28 97.2 0.1 1.7e-27 96.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78377.1 - 7.3e-17 61.6 0.5 1.6e-16 60.5 0.5 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78377.1 - 1.1e-11 44.7 0.0 2.9e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAM104 PF15434.6 GBG78377.1 - 1.3 9.6 6.9 0.42 11.2 0.9 3.0 3 0 0 3 3 3 0 Family 104 Myb_DNA-binding PF00249.31 GBG78378.1 - 4.6e-07 29.9 0.1 9.6e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GBG78378.1 - 3.1e-05 23.8 0.1 7.7e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Lin-8 PF03353.15 GBG78379.1 - 0.82 9.2 24.6 1.5 8.3 4.9 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 GBG78379.1 - 2.2 7.6 26.7 3.2 7.1 11.3 2.2 2 0 0 2 2 2 0 SDA1 Integrase_H2C2 PF17921.1 GBG78380.1 - 1.7e-15 56.8 0.8 3.5e-15 55.8 0.8 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-RING_UBOX PF13445.6 GBG78381.1 - 2.1e-07 30.9 2.3 8.4e-07 28.9 2.3 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GBG78381.1 - 2.9e-07 30.5 2.6 2.9e-07 30.5 2.6 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GBG78381.1 - 5.8e-06 26.1 0.7 2.8e-05 23.9 0.7 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG78381.1 - 7.4e-06 25.7 0.5 4.5e-05 23.2 0.5 2.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 GBG78381.1 - 4.3e-05 23.6 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain V-ATPase_H_N PF03224.14 GBG78381.1 - 0.00046 19.6 8.0 1.1 8.5 0.0 6.2 6 1 0 6 6 6 2 V-ATPase subunit H Arm PF00514.23 GBG78381.1 - 0.00093 19.2 37.6 0.23 11.6 0.1 13.9 17 1 1 18 18 18 2 Armadillo/beta-catenin-like repeat zf-RING_2 PF13639.6 GBG78381.1 - 0.0042 17.4 4.5 0.027 14.8 4.5 2.6 1 0 0 1 1 1 1 Ring finger domain UNC45-central PF11701.8 GBG78381.1 - 0.013 15.5 1.3 1.5 8.7 0.1 4.5 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Baculo_IE-1 PF05290.11 GBG78381.1 - 0.015 15.3 0.3 0.015 15.3 0.3 2.7 3 0 0 3 3 2 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 GBG78381.1 - 0.015 15.1 1.9 0.047 13.5 0.6 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 HEAT_2 PF13646.6 GBG78381.1 - 0.017 15.5 22.6 1.1 9.7 0.1 8.9 10 1 0 10 10 8 0 HEAT repeats TAF6_C PF07571.13 GBG78381.1 - 0.028 14.7 0.2 1.7 9.0 0.0 3.6 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain PUL PF08324.11 GBG78381.1 - 0.11 11.7 6.0 0.69 9.1 0.0 3.6 4 0 0 4 4 4 0 PUL domain tRNA_anti-codon PF01336.25 GBG78382.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RVT_1 PF00078.27 GBG78383.1 - 2.1e-11 43.8 0.1 2.9e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG78383.1 - 0.14 10.3 8.6 0.17 10.1 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG78383.1 - 0.53 9.7 9.5 0.66 9.3 9.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG78383.1 - 0.56 8.4 6.9 0.72 8.1 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG78383.1 - 7.3 5.8 13.3 9.7 5.4 13.3 1.1 1 0 0 1 1 1 0 BUD22 Homoserine_dh PF00742.19 GBG78384.1 - 1.5e-53 181.3 0.0 5e-53 179.6 0.0 2.0 2 0 0 2 2 2 1 Homoserine dehydrogenase AA_kinase PF00696.28 GBG78384.1 - 8.2e-41 140.2 0.0 1.5e-40 139.3 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 GBG78384.1 - 5.1e-19 67.7 0.2 1.1e-08 34.7 0.0 2.8 2 0 0 2 2 2 2 ACT domain NAD_binding_3 PF03447.16 GBG78384.1 - 3.1e-17 63.3 0.0 1.6e-16 61.0 0.0 2.2 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.6 GBG78384.1 - 6.4e-14 51.5 1.4 1.1e-07 31.6 0.1 2.5 2 0 0 2 2 2 2 ACT domain Thioredoxin PF00085.20 GBG78385.1 - 8.5e-16 57.8 0.1 1.8e-09 37.5 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin DUF4301 PF14134.6 GBG78385.1 - 0.00026 19.9 3.8 0.00036 19.5 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4301) Thioredoxin_7 PF13899.6 GBG78385.1 - 0.0013 18.9 0.3 0.077 13.2 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GBG78385.1 - 0.0075 16.6 4.8 1.4 9.3 0.7 3.7 3 1 1 4 4 4 1 Thioredoxin-like HyaE PF07449.11 GBG78385.1 - 0.0081 16.1 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 GBG78385.1 - 0.014 15.8 8.9 0.31 11.5 0.1 3.5 2 2 0 2 2 2 0 Thioredoxin-like domain CENP-N PF05238.13 GBG78385.1 - 0.42 9.9 4.7 0.66 9.2 4.7 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like zf-CCHC PF00098.23 GBG78387.1 - 1.1e-42 142.2 64.2 2.5e-06 27.3 0.7 9.2 9 0 0 9 9 9 9 Zinc knuckle zf-CCHC_3 PF13917.6 GBG78387.1 - 1.5e-13 50.4 41.4 0.01 15.8 0.1 8.9 3 3 5 8 8 8 7 Zinc knuckle zf-CCHC_2 PF13696.6 GBG78387.1 - 7e-12 44.9 65.1 0.0031 17.3 1.6 9.4 9 0 0 9 9 9 9 Zinc knuckle zf-CCHC_4 PF14392.6 GBG78387.1 - 3.1e-08 33.2 56.6 0.39 10.5 2.0 9.2 9 0 0 9 9 9 8 Zinc knuckle zf-CCHC_5 PF14787.6 GBG78387.1 - 3.2e-06 26.7 52.9 0.08 12.7 1.8 9.1 4 2 5 9 9 9 8 GAG-polyprotein viral zinc-finger RVT_1 PF00078.27 GBG78388.1 - 5.8e-24 84.9 0.1 8.6e-24 84.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mucin PF01456.17 GBG78391.1 - 0.054 13.5 1.2 0.054 13.5 1.2 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein gag-asp_proteas PF13975.6 GBG78393.1 - 6e-08 33.1 0.1 1.7e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78393.1 - 9.3e-06 26.2 0.1 2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG78393.1 - 0.0002 21.2 0.2 0.00031 20.5 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG78393.1 - 0.0057 16.4 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG78393.1 - 0.014 15.0 0.3 0.026 14.2 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RT_RNaseH_2 PF17919.1 GBG78394.1 - 3.9e-27 94.2 0.0 6.6e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78394.1 - 2.8e-20 72.6 0.0 5.1e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78394.1 - 0.0022 17.6 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop53 PF07767.11 GBG78394.1 - 0.016 14.6 26.4 0.025 14.0 26.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GBG78394.1 - 0.52 8.5 19.6 0.79 7.9 19.6 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG78394.1 - 2.1 7.7 31.9 2.8 7.3 31.9 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG78394.1 - 2.6 7.3 30.5 3.7 6.8 30.5 1.1 1 0 0 1 1 1 0 BUD22 DUF572 PF04502.13 GBG78394.1 - 3.2 7.3 18.1 4.5 6.8 18.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) LAP1C PF05609.12 GBG78394.1 - 3.3 6.7 17.4 4.4 6.3 17.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DNA_pol_phi PF04931.13 GBG78394.1 - 4.8 5.2 30.4 6.5 4.7 30.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 GBG78394.1 - 4.8 5.2 16.1 6.5 4.7 16.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.15 GBG78394.1 - 7.1 6.1 20.5 12 5.3 20.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG78394.1 - 9.4 4.3 31.3 13 3.8 31.3 1.1 1 0 0 1 1 1 0 Nop14-like family TEBP_beta PF07404.11 GBG78395.1 - 5.8 6.2 7.9 7.6 5.8 7.9 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Tautomerase PF01361.21 GBG78395.1 - 6.1 6.9 7.6 4.9 7.2 3.2 2.8 2 1 1 3 3 3 0 Tautomerase enzyme RVT_1 PF00078.27 GBG78396.1 - 1.5e-29 103.1 0.3 2.9e-29 102.2 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78396.1 - 4.3e-17 62.0 0.0 1.1e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78396.1 - 1.3e-09 38.3 0.0 1.2e-08 35.1 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG78396.1 - 0.15 12.3 3.3 0.18 12.1 0.2 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein VirC1 PF07015.11 GBG78397.1 - 0.0088 15.4 3.0 1.1 8.5 0.2 2.1 1 1 1 2 2 2 2 VirC1 protein Lzipper-MIP1 PF14389.6 GBG78397.1 - 0.014 15.7 4.6 0.019 15.3 4.3 1.4 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 RVT_1 PF00078.27 GBG78398.1 - 9.5e-53 179.0 0.2 2e-32 112.5 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78398.1 - 3.3e-32 110.5 0.1 7.2e-32 109.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78398.1 - 4.6e-25 87.9 0.0 1.2e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78398.1 - 8e-16 57.9 0.1 2.2e-15 56.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain She9_MDM33 PF05546.11 GBG78398.1 - 0.016 15.0 1.0 0.047 13.5 1.0 1.7 1 0 0 1 1 1 0 She9 / Mdm33 family zf-H2C2 PF09337.10 GBG78398.1 - 0.1 12.9 0.0 0.43 10.8 0.0 2.2 1 0 0 1 1 1 0 H2C2 zinc finger DUF5095 PF17016.5 GBG78398.1 - 0.11 12.2 0.7 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) DUF1640 PF07798.11 GBG78398.1 - 8.6 6.4 7.2 1.2 9.2 1.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) RT_RNaseH_2 PF17919.1 GBG78399.1 - 3.8e-29 100.7 0.1 2.2e-27 95.0 0.0 3.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78399.1 - 2.2e-26 92.2 0.4 7.2e-25 87.3 0.0 3.2 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78399.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG78399.1 - 0.29 10.7 0.0 0.29 10.7 0.0 3.4 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Flavodoxin_1 PF00258.25 GBG78400.1 - 2.1e-24 86.3 0.4 6.4e-24 84.8 0.1 1.9 2 0 0 2 2 2 1 Flavodoxin ThiC-associated PF13667.6 GBG78400.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 ThiC-associated domain RT_RNaseH PF17917.1 GBG78402.1 - 4.8e-19 68.6 0.0 8e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78402.1 - 9.1e-17 60.9 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG78403.1 - 0.0076 16.0 0.3 0.019 14.7 0.3 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CENP-F_leu_zip PF10473.9 GBG78403.1 - 0.0084 16.1 13.2 0.019 15.0 13.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ORF_2_N PF18492.1 GBG78404.1 - 5.9e-05 23.3 0.0 7.8 6.7 0.0 5.2 4 2 1 6 6 6 2 Open reading frame 2 N-terminal domain PapC_C PF13953.6 GBG78404.1 - 0.00051 19.8 42.2 5.8 6.8 0.2 10.2 2 2 9 12 12 12 5 PapC C-terminal domain Methyltransf_1N PF02870.15 GBG78404.1 - 0.00066 20.4 16.8 12 6.8 0.3 8.2 5 3 4 9 9 9 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain RTA1 PF04479.13 GBG78404.1 - 0.0075 15.9 18.7 47 3.5 0.0 9.5 4 3 9 13 13 13 0 RTA1 like protein FBA_3 PF08268.12 GBG78404.1 - 0.12 12.3 23.1 9.6 6.2 0.1 6.3 1 1 5 6 6 6 0 F-box associated domain ImpE PF07024.13 GBG78404.1 - 1.3 9.1 23.3 33 4.6 0.0 8.6 3 3 6 11 11 11 0 ImpE protein RT_RNaseH_2 PF17919.1 GBG78407.1 - 1.9e-28 98.4 0.0 4.4e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78407.1 - 1e-25 90.0 0.1 2.1e-25 89.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PET117 PF15786.5 GBG78407.1 - 0.95 9.8 4.2 2.5 8.4 4.2 1.7 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial SelP_N PF04592.14 GBG78407.1 - 1 8.7 6.9 2 7.8 6.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RT_RNaseH_2 PF17919.1 GBG78408.1 - 3.7e-19 68.6 0.0 7.7e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78408.1 - 1.5e-18 67.0 0.0 1.3e-17 64.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78408.1 - 4.8e-05 23.0 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG78408.1 - 0.011 16.0 0.1 0.052 13.8 0.0 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG78408.1 - 0.025 14.4 1.3 0.043 13.6 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Strep_SA_rep PF06696.11 GBG78408.1 - 0.16 12.0 2.0 0.22 11.6 0.2 2.2 2 0 0 2 2 2 0 Streptococcal surface antigen repeat RT_RNaseH_2 PF17919.1 GBG78409.1 - 1.4e-24 86.0 0.0 2.5e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78409.1 - 3.2e-22 78.8 0.0 1.3e-21 76.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78409.1 - 5e-11 42.8 0.0 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG78409.1 - 2.5e-05 23.9 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG78409.1 - 0.0036 17.0 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG78411.1 - 7.4e-66 221.8 0.3 1.1e-31 110.1 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78411.1 - 1.1e-60 201.9 0.0 1.6e-29 101.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78411.1 - 4.1e-58 194.2 0.5 1.6e-29 102.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78411.1 - 1.2e-33 115.8 0.0 8.5e-16 58.2 0.0 4.0 4 0 0 4 4 4 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG78411.1 - 9.3e-33 112.1 1.7 5e-18 65.0 0.1 3.0 3 0 0 3 3 3 2 Integrase zinc binding domain RVP_2 PF08284.11 GBG78411.1 - 6.1e-07 29.3 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG78411.1 - 2.4e-05 24.4 0.0 0.083 13.1 0.0 2.8 2 0 0 2 2 2 2 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG78411.1 - 0.00015 22.3 0.0 0.00035 21.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Rhamno_transf PF11316.8 GBG78411.1 - 0.00037 20.0 0.2 0.09 12.1 0.0 2.5 2 0 0 2 2 2 1 Putative rhamnosyl transferase gag-asp_proteas PF13975.6 GBG78411.1 - 0.00037 21.0 0.0 0.001 19.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease WD40 PF00400.32 GBG78411.1 - 0.00053 20.7 12.8 0.35 11.8 0.3 6.1 5 1 0 5 5 5 1 WD domain, G-beta repeat rve_3 PF13683.6 GBG78411.1 - 0.0082 15.9 0.1 5.1 7.0 0.0 3.2 2 0 0 2 2 2 1 Integrase core domain SH3_16 PF18348.1 GBG78411.1 - 0.033 14.0 0.1 4.9 7.0 0.0 2.7 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF1758 PF05585.12 GBG78411.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) TEX19 PF15553.6 GBG78412.1 - 0.1 12.5 4.5 0.037 14.0 1.2 2.0 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF2434 PF10361.9 GBG78412.1 - 0.14 11.1 0.2 0.23 10.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) WD40 PF00400.32 GBG78412.1 - 0.14 13.1 10.2 12 7.0 0.1 4.7 4 1 0 4 4 4 0 WD domain, G-beta repeat BUD22 PF09073.10 GBG78414.1 - 2 7.6 11.3 2.1 7.6 11.3 1.1 1 0 0 1 1 1 0 BUD22 DUF2921 PF11145.8 GBG78415.1 - 2e-18 65.7 7.7 1e-06 27.0 0.0 4.4 3 2 0 3 3 3 3 Protein of unknown function (DUF2921) Bindin PF02084.15 GBG78416.1 - 0.022 15.0 5.4 0.027 14.8 5.4 1.1 1 0 0 1 1 1 0 Bindin GRP PF07172.11 GBG78416.1 - 0.027 15.2 13.6 0.034 14.8 13.6 1.1 1 0 0 1 1 1 0 Glycine rich protein family XS PF03468.14 GBG78421.1 - 1.3e-28 99.5 2.6 1.6e-28 99.2 0.1 2.4 2 1 0 2 2 2 1 XS domain RT_RNaseH PF17917.1 GBG78421.1 - 1.8e-18 66.8 0.2 1.8e-18 66.8 0.2 2.3 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78421.1 - 1e-15 57.9 0.2 2.1e-15 56.8 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78421.1 - 1.5e-10 41.0 2.5 1.6e-10 40.9 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-TRAF PF02176.18 GBG78422.1 - 3.8e-13 49.9 16.4 7.5e-08 33.0 7.1 3.0 1 1 1 2 2 2 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 GBG78422.1 - 2.5e-07 30.5 3.6 2.5e-07 30.5 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG78422.1 - 6.8e-07 29.0 4.8 6.8e-07 29.0 4.8 3.1 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG78422.1 - 8.6e-06 25.5 5.2 8.6e-06 25.5 5.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG78422.1 - 3.5e-05 23.9 5.1 3.5e-05 23.9 5.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.5 GBG78422.1 - 5.3e-05 23.6 16.8 0.0005 20.5 8.0 3.3 2 1 1 3 3 3 2 TRAF-like zinc-finger Sina PF03145.16 GBG78422.1 - 0.00011 22.3 12.3 0.036 14.0 2.8 2.7 1 1 2 3 3 3 2 Seven in absentia protein family zf-RING_UBOX PF13445.6 GBG78422.1 - 0.00078 19.4 5.4 0.00078 19.4 5.4 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG78422.1 - 0.0013 18.7 5.4 0.0013 18.7 5.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GBG78422.1 - 0.0072 16.6 7.2 0.0072 16.6 7.2 3.1 2 1 1 3 3 1 1 Ring finger domain zf_UBZ PF18439.1 GBG78422.1 - 0.051 13.2 0.7 0.2 11.3 0.7 2.1 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-U11-48K PF05253.12 GBG78422.1 - 0.11 12.4 4.7 17 5.5 0.0 3.8 4 0 0 4 4 4 0 U11-48K-like CHHC zinc finger zf-C3HC4_5 PF17121.5 GBG78422.1 - 0.13 12.1 6.5 0.47 10.4 6.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GBG78422.1 - 0.43 10.5 5.1 1.7 8.6 5.1 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DM PF00751.18 GBG78422.1 - 0.58 10.1 9.6 3.1 7.8 1.7 3.8 2 1 1 3 3 3 0 DM DNA binding domain Prok-RING_4 PF14447.6 GBG78422.1 - 1.2 9.0 17.0 0.039 13.8 6.5 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 rve PF00665.26 GBG78423.1 - 3.9e-18 65.8 0.0 8.7e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78423.1 - 0.0033 17.5 3.6 0.0068 16.5 3.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG78423.1 - 0.021 14.7 0.0 0.078 12.9 0.0 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain LcrG PF07216.12 GBG78423.1 - 0.055 13.4 1.0 0.14 12.1 1.0 1.6 1 0 0 1 1 1 0 LcrG protein RVT_1 PF00078.27 GBG78424.1 - 1.5e-32 112.9 0.0 2.8e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78424.1 - 7.8e-17 61.6 0.0 1.7e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78424.1 - 1.2e-15 57.3 0.1 4.2e-14 52.4 0.1 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78424.1 - 0.0018 18.4 0.0 0.023 14.9 0.0 2.6 2 0 0 2 2 2 1 H2C2 zinc finger CCD48 PF15799.5 GBG78424.1 - 0.0023 16.3 2.2 0.0037 15.6 2.2 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 HALZ PF02183.18 GBG78424.1 - 0.042 14.1 3.7 0.11 12.8 3.7 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper rve_3 PF13683.6 GBG78424.1 - 0.084 12.7 0.0 0.35 10.7 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain CCDC85 PF10226.9 GBG78424.1 - 0.14 11.8 0.2 0.37 10.4 0.2 1.6 1 0 0 1 1 1 0 CCDC85 family YscO PF07321.12 GBG78424.1 - 0.88 9.5 9.0 3 7.8 9.0 1.9 1 0 0 1 1 1 0 Type III secretion protein YscO CRISPR_Cse2 PF09485.10 GBG78424.1 - 3.7 8.1 6.3 4.3 7.8 3.4 2.3 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) bZIP_1 PF00170.21 GBG78424.1 - 6.1 7.0 7.2 0.93 9.6 2.4 2.1 2 0 0 2 2 1 0 bZIP transcription factor UCH PF00443.29 GBG78426.1 - 1e-63 215.2 0.0 1.3e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG78426.1 - 5.2e-19 69.0 0.0 3.6e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase BUD22 PF09073.10 GBG78426.1 - 4.2 6.6 5.9 9.3 5.5 5.9 1.5 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 GBG78426.1 - 8 6.3 14.2 18 5.1 0.2 2.2 2 0 0 2 2 2 0 SPX domain Mito_carr PF00153.27 GBG78428.1 - 7.2e-74 243.8 1.8 1.4e-25 89.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF659 PF04937.15 GBG78430.1 - 2.6e-14 53.4 0.0 4.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ATP_bind_1 PF03029.17 GBG78431.1 - 1.7e-68 231.0 0.3 1.9e-68 230.8 0.3 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Glyco_hydro_32N PF00251.20 GBG78432.1 - 3.7e-94 315.7 0.0 4.9e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 GBG78432.1 - 4.5e-22 78.7 0.0 6.9e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal RT_RNaseH_2 PF17919.1 GBG78433.1 - 1.5e-33 114.8 0.0 2.5e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78433.1 - 2e-30 105.2 0.2 3.7e-30 104.3 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78433.1 - 2.3e-19 69.3 1.5 6e-19 67.9 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG78433.1 - 5.3e-09 36.3 0.0 1.2e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG78433.1 - 0.0016 18.6 0.0 0.0051 17.0 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger tRNA_edit PF04073.15 GBG78434.1 - 1.1e-07 31.9 0.0 4.1e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain CLZ PF16526.5 GBG78434.1 - 0.42 11.0 3.9 0.39 11.1 2.2 1.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 GBG78434.1 - 0.85 9.5 8.7 6.5 6.7 0.1 3.1 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Tau95_N PF17682.1 GBG78435.1 - 8.6e-30 103.5 0.3 2.5e-21 76.2 0.0 3.2 3 0 0 3 3 3 2 Tau95 Triple barrel domain Tau95 PF09734.9 GBG78435.1 - 2.9e-17 63.8 0.8 4.4e-15 56.7 0.4 2.8 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tub_N PF16322.5 GBG78435.1 - 0.0095 16.4 11.5 0.0098 16.3 3.7 3.1 2 1 0 2 2 2 1 Tubby N-terminal SDA1 PF05285.12 GBG78435.1 - 1.1 8.6 23.5 0.017 14.5 12.6 2.6 3 0 0 3 3 3 0 SDA1 Importin_rep_4 PF18808.1 GBG78435.1 - 1.6 9.1 9.3 3.9 7.8 9.3 1.7 1 0 0 1 1 1 0 Importin repeat Vfa1 PF08432.10 GBG78435.1 - 5 7.4 9.6 0.63 10.3 4.2 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RRM_1 PF00076.22 GBG78436.1 - 1.8e-34 117.3 0.6 8.5e-17 60.8 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG78436.1 - 6.7e-14 51.8 0.4 1.4e-06 28.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GBG78436.1 - 0.0074 16.3 0.1 0.71 9.9 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 GBG78436.1 - 0.011 16.0 0.4 6.7 6.9 0.0 3.1 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 GBG78436.1 - 0.12 12.5 0.3 8.3 6.5 0.1 2.2 2 0 0 2 2 2 0 RNA binding motif RL PF17797.1 GBG78436.1 - 0.15 12.0 0.0 1.6 8.7 0.1 2.1 2 0 0 2 2 2 0 RL domain DUF659 PF04937.15 GBG78439.1 - 4.1e-28 98.2 0.0 8.5e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PCB_OB PF17092.5 GBG78439.1 - 0.13 13.0 3.1 0.39 11.5 3.1 1.8 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain DUF659 PF04937.15 GBG78440.1 - 1.7e-14 54.0 0.0 2.5e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CDC45 PF02724.14 GBG78440.1 - 9.4 4.4 16.4 0.074 11.3 8.0 1.6 2 0 0 2 2 2 0 CDC45-like protein DUF659 PF04937.15 GBG78441.1 - 5.7e-18 65.2 0.1 2.3e-17 63.2 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) ATP-synt_ab PF00006.25 GBG78442.1 - 3.7e-68 229.4 0.0 6.7e-68 228.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GBG78442.1 - 1.6e-14 54.1 1.7 2.9e-14 53.3 1.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Chromo PF00385.24 GBG78443.1 - 1.8e-12 46.9 0.0 5.7e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG78443.1 - 0.0014 18.8 0.1 0.0059 16.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG78443.1 - 0.011 16.4 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG78443.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG78444.1 - 0.021 15.1 1.1 0.068 13.5 0.4 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein DUF1869 PF08956.10 GBG78444.1 - 0.093 12.6 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) DUF659 PF04937.15 GBG78445.1 - 6.2e-13 48.9 0.2 1.6e-12 47.5 0.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG78446.1 - 7.5e-26 90.8 0.1 2e-25 89.4 0.0 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78446.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG78447.1 - 0.26 11.1 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Presenilin PF01080.17 GBG78448.1 - 4.3 6.0 27.8 5.8 5.6 27.8 1.1 1 0 0 1 1 1 0 Presenilin BAF1_ABF1 PF04684.13 GBG78448.1 - 6.4 5.7 24.7 9.3 5.2 24.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF421 PF04239.12 GBG78449.1 - 0.05 13.4 0.5 0.11 12.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF421) EDR1 PF14381.6 GBG78449.1 - 0.16 11.7 1.6 0.51 10.0 1.6 1.9 1 1 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 HIP1_clath_bdg PF16515.5 GBG78449.1 - 5.7 7.6 21.0 0.14 12.8 6.4 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RGS-like PF09128.11 GBG78451.1 - 0.31 10.7 7.3 0.37 10.5 7.3 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Utp11 PF03998.13 GBG78452.1 - 9.4e-61 205.8 20.9 1.2e-60 205.5 20.9 1.1 1 0 0 1 1 1 1 Utp11 protein APP_amyloid PF10515.9 GBG78452.1 - 0.11 13.0 0.7 0.46 11.0 0.1 2.4 2 0 0 2 2 2 0 Beta-amyloid precursor protein C-terminus AAA_11 PF13086.6 GBG78452.1 - 1.4 8.6 6.6 1.8 8.3 6.6 1.1 1 0 0 1 1 1 0 AAA domain FOXP-CC PF16159.5 GBG78452.1 - 2.4 8.8 4.7 1.7 9.3 0.6 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain Ribosom_S12_S23 PF00164.25 GBG78453.1 - 3.3e-50 168.5 0.6 4.1e-50 168.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PRP38_assoc PF12871.7 GBG78454.1 - 6.8 7.4 19.0 0.2 12.2 0.6 3.3 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Pkinase_Tyr PF07714.17 GBG78456.1 - 1e-43 149.5 0.0 1.5e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG78456.1 - 1.1e-38 133.1 0.0 1.7e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Malectin_like PF12819.7 GBG78456.1 - 2.9e-32 112.2 0.0 3.7e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Malectin-like domain Malectin PF11721.8 GBG78456.1 - 9.2e-22 77.9 0.0 1.3e-09 38.3 0.0 2.4 2 0 0 2 2 2 2 Malectin domain LRRNT_2 PF08263.12 GBG78456.1 - 3.2e-05 24.1 0.0 8.2e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 GBG78456.1 - 0.00062 19.5 4.3 0.00062 19.5 4.3 2.0 2 0 0 2 2 2 1 Leucine rich repeat PIP49_C PF12260.8 GBG78456.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 GBG78456.1 - 0.18 11.7 0.0 0.51 10.2 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_1 PF00560.33 GBG78456.1 - 0.79 10.5 2.1 33 5.6 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 GBG78456.1 - 2.4 8.7 8.5 3.7 8.1 1.8 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Integrase_H2C2 PF17921.1 GBG78457.1 - 1.9e-19 69.5 1.7 3.8e-19 68.5 1.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78457.1 - 2e-19 69.9 0.0 4.5e-19 68.8 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG78457.1 - 0.0038 17.4 0.2 0.0077 16.4 0.2 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Cpn60_TCP1 PF00118.24 GBG78458.1 - 3.4e-151 504.2 10.7 3.9e-151 504.0 10.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATP-grasp_2 PF08442.10 GBG78459.1 - 6.9e-60 202.1 2.2 1.2e-59 201.3 2.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 GBG78459.1 - 3.9e-27 95.0 4.5 7.5e-27 94.0 4.5 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 GBG78459.1 - 8.2e-08 32.0 1.3 1.4e-07 31.2 1.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GBG78459.1 - 0.0012 18.6 0.8 0.0043 16.8 0.8 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SASA PF03629.18 GBG78459.1 - 0.051 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase Succ_CoA_lig PF13607.6 GBG78459.1 - 0.068 13.0 0.7 0.16 11.8 0.7 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain RT_RNaseH_2 PF17919.1 GBG78460.1 - 2.2e-24 85.4 0.0 4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78460.1 - 7e-24 84.1 0.0 1.2e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78460.1 - 1.4e-18 66.8 0.3 1.4e-18 66.8 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG78460.1 - 2.2e-09 37.5 0.0 6.9e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG78460.1 - 7.5e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78460.1 - 2.2e-06 28.2 0.0 3.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78460.1 - 9.2e-06 26.1 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG78460.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG78460.1 - 0.0031 17.7 1.1 0.11 12.8 1.7 3.2 3 1 0 3 3 3 1 H2C2 zinc finger ABC_membrane_2 PF06472.15 GBG78462.1 - 8.1e-32 110.7 1.8 1.4e-31 109.9 1.8 1.3 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 GBG78462.1 - 1.5e-11 44.3 5.1 4.5e-06 26.3 1.4 2.3 1 1 1 2 2 2 2 SbmA/BacA-like family ABC_membrane PF00664.23 GBG78462.1 - 0.0075 16.0 0.8 0.0075 16.0 0.8 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_membrane_2 PF06472.15 GBG78463.1 - 1.2e-57 195.4 4.2 1.2e-57 195.4 4.2 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 GBG78463.1 - 3.3e-18 66.2 7.5 1.3e-17 64.3 7.5 1.8 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_tran PF00005.27 GBG78463.1 - 4.7e-17 62.8 0.0 2.6e-16 60.4 0.0 2.3 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GBG78463.1 - 7.8e-06 25.7 10.2 1.3e-05 25.0 10.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GBG78463.1 - 0.00015 21.2 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 GBG78463.1 - 0.0004 20.2 0.4 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GBG78463.1 - 0.00045 20.1 0.1 0.0052 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GBG78463.1 - 0.00056 20.3 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 GBG78463.1 - 0.0028 17.6 0.1 0.007 16.3 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 GBG78463.1 - 0.0071 16.1 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG78463.1 - 0.021 15.1 0.2 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GBG78463.1 - 0.022 15.1 0.0 0.062 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GBG78463.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 GBG78463.1 - 0.061 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 GBG78463.1 - 0.075 13.5 0.5 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GBG78463.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 GBG78463.1 - 0.14 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 GBG78463.1 - 0.18 11.2 0.1 0.39 10.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FAM184 PF15665.5 GBG78464.1 - 0.027 14.2 49.7 0.026 14.3 33.3 3.2 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B Filament PF00038.21 GBG78464.1 - 0.49 9.9 36.7 0.066 12.8 25.6 2.4 1 1 1 2 2 2 0 Intermediate filament protein Bacillus_HBL PF05791.11 GBG78464.1 - 1.8 8.4 11.2 0.73 9.6 0.9 2.9 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Polo_box_3 PF18544.1 GBG78464.1 - 5.2 7.8 7.8 0.72 10.5 1.7 2.6 2 1 0 2 2 2 0 Polo box domain Use1 PF09753.9 GBG78465.1 - 1.7e-47 162.2 0.5 2e-47 162.0 0.5 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4175 PF13779.6 GBG78465.1 - 0.005 14.8 11.4 0.0063 14.5 11.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) DUF5383 PF17355.2 GBG78465.1 - 0.015 15.7 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF2207 PF09972.9 GBG78465.1 - 0.056 12.2 0.1 0.072 11.8 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5082 PF16888.5 GBG78465.1 - 0.065 13.5 1.3 1.2 9.4 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) zf-LITAF-like PF10601.9 GBG78465.1 - 0.3 11.4 1.5 0.5 10.7 1.5 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain RVP_2 PF08284.11 GBG78466.1 - 8e-08 32.1 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG78466.1 - 2.2e-06 27.4 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG78466.1 - 8.5e-06 26.3 0.0 1.7e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78466.1 - 0.00019 21.9 0.0 0.00064 20.2 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG78466.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG78466.1 - 0.0039 17.0 0.0 0.014 15.2 0.1 1.8 2 1 0 2 2 2 1 Aspartyl protease DUF4392 PF14336.6 GBG78466.1 - 0.034 13.6 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) GATase_4 PF13230.6 GBG78466.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II RT_RNaseH_2 PF17919.1 GBG78467.1 - 1.4e-25 89.2 0.0 2.7e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78467.1 - 1e-23 83.6 0.0 2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78467.1 - 5.1e-19 68.1 1.3 1.4e-18 66.8 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG78467.1 - 9.8e-17 61.2 0.0 1.7e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG78467.1 - 0.0049 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG78467.1 - 0.015 15.4 0.1 0.051 13.8 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Myb_DNA-bind_4 PF13837.6 GBG78468.1 - 2.7e-10 40.5 1.4 9.2e-10 38.8 1.0 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG78468.1 - 0.0073 16.4 1.5 0.017 15.2 1.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG78468.1 - 0.42 11.0 1.7 0.67 10.3 0.2 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF659 PF04937.15 GBG78470.1 - 1.8e-12 47.3 0.0 3.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78471.1 - 0.0018 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region GCHY-1 PF02649.14 GBG78471.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 zf-C2H2_6 PF13912.6 GBG78473.1 - 0.00054 19.9 1.9 0.0014 18.6 1.9 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GBG78473.1 - 0.0018 19.0 0.3 0.0056 17.4 0.3 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 GBG78473.1 - 0.014 15.8 0.4 0.041 14.3 0.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3584 PF12128.8 GBG78474.1 - 0.0004 18.1 12.4 0.0004 18.1 12.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Ndc1_Nup PF09531.10 GBG78474.1 - 2.1 6.9 4.4 2.2 6.8 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3332 PF11810.8 GBG78474.1 - 4.8 6.8 6.4 1.3 8.6 3.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) Fzo_mitofusin PF04799.13 GBG78474.1 - 5.3 6.6 6.6 1.7 8.2 0.1 2.7 2 1 1 3 3 3 0 fzo-like conserved region LPP PF04728.13 GBG78474.1 - 6.7 7.2 10.8 48 4.4 6.0 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper SDA1 PF05285.12 GBG78475.1 - 0.00061 19.3 52.2 0.00074 19.1 52.2 1.1 1 0 0 1 1 1 1 SDA1 Caldesmon PF02029.15 GBG78475.1 - 0.042 12.6 51.6 0.047 12.5 51.6 1.1 1 0 0 1 1 1 0 Caldesmon Lin-8 PF03353.15 GBG78475.1 - 6 6.3 28.8 9.3 5.7 28.8 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG78475.1 - 9.2 4.3 63.0 14 3.8 63.0 1.2 1 0 0 1 1 1 0 Nop14-like family rve PF00665.26 GBG78476.1 - 2.3e-14 53.6 0.0 4.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78476.1 - 0.025 14.7 0.6 0.052 13.7 0.6 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain DUF1564 PF07600.11 GBG78476.1 - 0.045 13.4 0.0 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DUF659 PF04937.15 GBG78477.1 - 1.1e-35 122.7 0.0 2e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78477.1 - 1e-06 28.4 2.3 1.2e-06 28.2 0.5 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG78477.1 - 1.9 8.6 7.0 8.3 6.7 7.0 2.2 1 0 0 1 1 1 0 AT hook motif Integrase_H2C2 PF17921.1 GBG78478.1 - 1.3e-19 70.0 0.3 2.6e-19 69.1 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78478.1 - 3.9e-15 56.1 0.0 7.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG78478.1 - 0.014 15.6 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DUF1564 PF07600.11 GBG78478.1 - 0.085 12.5 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG78479.1 - 0.0011 19.2 0.2 0.0011 19.2 0.2 2.8 3 1 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG78480.1 - 7.7e-31 107.3 0.1 1.2e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78480.1 - 3.5e-24 84.7 0.0 7.5e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78480.1 - 6.9e-20 71.3 0.0 1.2e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78481.1 - 1.4e-26 92.4 0.0 3.1e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78481.1 - 2e-21 76.2 0.0 5.2e-21 74.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78481.1 - 9.4e-13 48.2 0.4 4.1e-07 29.7 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG78481.1 - 8.2e-07 29.6 0.0 1.8e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78481.1 - 5.1e-05 23.8 0.0 9.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG78481.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG78481.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH PF17917.1 GBG78482.1 - 1.2e-11 44.8 0.1 4.9e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG78482.1 - 6.7e-09 36.2 0.0 1.3e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78482.1 - 7e-09 36.2 0.0 1.4e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG78482.1 - 1.6e-06 27.9 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG78482.1 - 8.1e-06 25.8 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG78482.1 - 4.4e-05 23.3 0.0 8.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG78482.1 - 0.0089 16.3 0.2 0.0089 16.3 0.2 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG78482.1 - 0.015 15.1 0.7 0.036 13.8 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RT_RNaseH PF17917.1 GBG78483.1 - 4.7e-12 46.1 0.7 1.7e-11 44.3 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78483.1 - 2.7e-06 27.3 0.0 6.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG78483.1 - 0.0053 17.0 0.2 0.0053 17.0 0.2 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG78483.1 - 0.022 14.5 1.9 0.054 13.3 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Chromo PF00385.24 GBG78483.1 - 0.098 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Surfac_D-trimer PF09006.11 GBG78484.1 - 0.19 11.6 4.2 0.7 9.8 0.0 3.1 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation GAS PF13851.6 GBG78484.1 - 3.4 7.0 25.7 0.94 8.8 13.9 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding RT_RNaseH_2 PF17919.1 GBG78485.1 - 2.3e-16 59.6 0.1 7.9e-16 57.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78485.1 - 7.7e-12 45.2 0.3 1.5e-11 44.2 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78485.1 - 4.4e-06 26.9 0.0 2.1e-05 24.8 0.0 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78485.1 - 0.017 15.3 0.1 0.044 14.0 0.1 1.7 1 1 0 1 1 1 0 Integrase core domain DUF3243 PF11588.8 GBG78485.1 - 0.18 12.2 4.9 0.18 12.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3243) Nop14 PF04147.12 GBG78486.1 - 0.11 10.7 31.3 0.11 10.7 31.3 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG78486.1 - 0.32 9.1 47.7 0.36 8.9 47.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 GBG78486.1 - 0.38 9.1 23.2 0.4 9.1 23.2 1.0 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 GBG78486.1 - 0.58 8.4 25.4 0.7 8.1 25.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 GBG78486.1 - 2.9 8.3 4.2 3.7 8.0 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 BAF1_ABF1 PF04684.13 GBG78486.1 - 4.3 6.3 15.8 4.8 6.1 15.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nop25 PF09805.9 GBG78486.1 - 5.2 7.5 14.9 5.9 7.4 14.9 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SDA1 PF05285.12 GBG78486.1 - 8.9 5.6 35.7 10 5.4 35.7 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG78487.1 - 0.11 10.7 31.3 0.11 10.7 31.3 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG78487.1 - 0.32 9.1 47.7 0.36 8.9 47.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 GBG78487.1 - 0.38 9.1 23.2 0.4 9.1 23.2 1.0 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 GBG78487.1 - 0.58 8.4 25.4 0.7 8.1 25.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 GBG78487.1 - 2.9 8.3 4.2 3.7 8.0 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 BAF1_ABF1 PF04684.13 GBG78487.1 - 4.3 6.3 15.8 4.8 6.1 15.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nop25 PF09805.9 GBG78487.1 - 5.2 7.5 14.9 5.9 7.4 14.9 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SDA1 PF05285.12 GBG78487.1 - 8.9 5.6 35.7 10 5.4 35.7 1.0 1 0 0 1 1 1 0 SDA1 rve PF00665.26 GBG78488.1 - 1.5e-08 34.8 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain PRTP PF01366.18 GBG78489.1 - 8.2 4.3 11.9 13 3.7 11.9 1.3 1 1 0 1 1 1 0 Herpesvirus processing and transport protein RVT_1 PF00078.27 GBG78490.1 - 4.9e-10 39.3 0.0 8.1e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cnn_1N PF07989.11 GBG78490.1 - 0.26 11.4 4.3 8.3 6.7 0.1 3.1 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 GBG78490.1 - 0.38 11.2 5.9 2.9 8.4 0.4 3.2 3 0 0 3 3 3 0 Cell division protein ZapB NUDE_C PF04880.13 GBG78490.1 - 1.5 9.2 7.3 1.7 9.1 2.5 2.5 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region TMF_TATA_bd PF12325.8 GBG78490.1 - 3.2 8.0 10.7 7.5 6.8 0.4 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding FabA PF07977.13 GBG78491.1 - 1.5e-34 118.6 0.0 1.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 GBG78491.1 - 6.2e-05 22.6 0.1 9.8e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.22 GBG78491.1 - 0.017 15.5 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily AAA PF00004.29 GBG78492.1 - 5.8e-39 133.5 0.0 1e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG78492.1 - 7.9e-08 32.0 0.0 1.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 GBG78492.1 - 3.4e-07 30.2 0.0 8.8e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 GBG78492.1 - 3.9e-05 23.7 0.1 0.0002 21.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG78492.1 - 0.00016 21.4 0.0 0.00034 20.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GBG78492.1 - 0.00037 19.8 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 GBG78492.1 - 0.00056 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GBG78492.1 - 0.00076 19.8 0.3 0.016 15.5 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG78492.1 - 0.0029 18.0 0.4 0.63 10.4 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 GBG78492.1 - 0.017 14.5 0.2 0.034 13.5 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GBG78492.1 - 0.024 14.2 0.1 0.18 11.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 GBG78492.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 GBG78492.1 - 0.054 13.5 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GBG78492.1 - 0.1 13.1 0.3 0.45 11.0 0.2 1.9 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 GBG78492.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PBP1_TM PF14812.6 GBG78492.1 - 0.28 11.6 4.5 0.87 10.0 4.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_18 PF13238.6 GBG78492.1 - 0.52 10.9 2.3 0.55 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain RVT_1 PF00078.27 GBG78493.1 - 1.7e-33 116.0 0.1 3e-33 115.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78493.1 - 3.3e-30 104.1 0.0 6.7e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78493.1 - 2.7e-26 91.9 0.0 5.6e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78493.1 - 4.8e-18 65.5 0.0 1.3e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78493.1 - 2.1e-15 56.6 0.1 5.2e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78493.1 - 6.3e-05 23.1 0.0 0.0004 20.5 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG78493.1 - 0.047 13.3 2.2 3.7 7.1 1.7 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase tRNA_lig_CPD PF08302.11 GBG78493.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain YabA PF06156.13 GBG78493.1 - 0.19 12.4 0.7 1.5 9.5 0.0 2.8 2 0 0 2 2 2 0 Initiation control protein YabA GCN5L1 PF06320.13 GBG78493.1 - 1.7 8.8 6.4 1.1 9.4 4.1 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) FUSC PF04632.12 GBG78493.1 - 9.5 4.6 7.1 5.8 5.3 0.1 2.3 1 1 1 2 2 2 0 Fusaric acid resistance protein family RT_RNaseH PF17917.1 GBG78494.1 - 5.7e-33 113.3 0.0 1.1e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78494.1 - 2.2e-30 104.6 0.0 4.6e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78494.1 - 2.3e-07 30.8 0.1 5.6e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78494.1 - 0.0005 20.2 0.1 0.0021 18.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG78494.1 - 0.0011 19.1 0.1 0.0028 17.8 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger UvrD-helicase PF00580.21 GBG78495.1 - 2.5e-22 79.8 2.0 3.3e-22 79.4 2.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 GBG78495.1 - 5.1e-12 46.4 0.3 1.1e-11 45.3 0.3 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG78495.1 - 0.0013 18.5 1.3 0.0018 18.0 0.3 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GBG78495.1 - 0.46 10.2 8.0 1.2 8.9 8.0 1.6 1 1 0 1 1 1 0 AAA domain Nucleo_P87 PF07267.11 GBG78495.1 - 6.3 5.5 7.3 8.6 5.1 7.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RT_RNaseH_2 PF17919.1 GBG78496.1 - 1.1e-28 99.2 0.0 4.7e-28 97.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78496.1 - 7.8e-27 93.6 0.0 1.8e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase UvrD-helicase PF00580.21 GBG78496.1 - 3.1e-15 56.5 0.3 3.1e-15 56.5 0.3 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain RVT_1 PF00078.27 GBG78496.1 - 0.00048 19.7 0.0 0.00092 18.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG78496.1 - 0.018 14.6 8.8 0.66 9.5 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Endostatin PF06482.11 GBG78496.1 - 0.18 11.2 2.0 0.38 10.2 2.0 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin HAUS6_N PF14661.6 GBG78496.1 - 0.33 10.5 7.1 0.74 9.4 7.1 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FdhE PF04216.12 GBG78496.1 - 3.4 7.5 7.4 7.3 6.4 7.4 1.5 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation RT_RNaseH_2 PF17919.1 GBG78497.1 - 2.5e-20 72.4 0.0 5.9e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78497.1 - 9.1e-16 58.1 0.0 2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78497.1 - 4.7e-14 52.2 1.5 2.2e-13 50.1 0.1 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG78497.1 - 7.2e-13 48.6 0.3 1.2e-12 47.8 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78497.1 - 4.7e-07 30.1 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG78497.1 - 0.029 14.6 0.0 0.071 13.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 GBG78497.1 - 0.045 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain FANCI_S1-cap PF14674.6 GBG78497.1 - 0.11 12.5 0.4 0.33 11.1 0.4 1.8 1 0 0 1 1 1 0 FANCI solenoid 1 cap DSHCT PF08148.12 GBG78498.1 - 2.9e-25 88.9 0.1 5.9e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 GBG78498.1 - 8.9e-14 51.6 0.0 2.2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GBG78498.1 - 0.0023 18.2 0.0 0.009 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain FYRC PF05965.14 GBG78498.1 - 0.0031 17.6 0.0 0.0085 16.2 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus AAA_30 PF13604.6 GBG78498.1 - 0.0054 16.5 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG78498.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain gag-asp_proteas PF13975.6 GBG78499.1 - 3.7e-08 33.8 0.1 2.7e-07 31.0 0.0 2.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG78499.1 - 2.9e-07 30.3 0.0 4.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG78499.1 - 1.8e-06 28.5 0.0 1e-05 26.1 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG78499.1 - 4.8e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG78499.1 - 0.00061 19.6 0.1 0.0013 18.6 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG78499.1 - 0.0016 18.7 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG78499.1 - 0.024 14.9 0.0 0.06 13.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG78505.1 - 4e-06 27.3 0.0 1.2e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78505.1 - 4.4e-06 27.3 0.0 1.8e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG78505.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG78505.1 - 0.00018 21.3 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG78505.1 - 0.019 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG78505.1 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MEIOC PF15189.6 GBG78506.1 - 0.03 13.9 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF2194 PF09960.9 GBG78506.1 - 0.11 10.8 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) DUF659 PF04937.15 GBG78507.1 - 2.6e-12 46.8 0.0 3.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG78510.1 - 6.3e-31 106.4 0.0 1.1e-14 54.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78510.1 - 2.2e-30 105.8 0.1 3.8e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78510.1 - 1.7e-29 102.2 0.0 3.6e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 GBG78513.1 - 1.1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG78513.1 - 6e-42 143.7 0.0 8.8e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CAP_GLY PF01302.25 GBG78513.1 - 3e-22 78.4 0.7 5.6e-22 77.5 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.6 GBG78513.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GBG78513.1 - 0.00016 20.6 0.1 0.0004 19.3 0.1 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GBG78513.1 - 0.044 13.1 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG78513.1 - 0.085 12.8 4.1 0.88 9.4 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GBG78513.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 GBG78514.1 - 1.1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG78514.1 - 6e-42 143.7 0.0 8.7e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CAP_GLY PF01302.25 GBG78514.1 - 1.6e-22 79.3 0.6 3e-22 78.4 0.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.6 GBG78514.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GBG78514.1 - 0.00016 20.6 0.1 0.0004 19.3 0.1 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GBG78514.1 - 0.044 13.1 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG78514.1 - 0.076 12.9 4.0 0.87 9.5 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GBG78514.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 GBG78515.1 - 1.1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG78515.1 - 6e-42 143.7 0.0 8.7e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CAP_GLY PF01302.25 GBG78515.1 - 1.6e-22 79.3 0.6 3e-22 78.4 0.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.6 GBG78515.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GBG78515.1 - 0.00016 20.6 0.1 0.0004 19.3 0.1 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GBG78515.1 - 0.044 13.1 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG78515.1 - 0.082 12.8 4.1 0.88 9.4 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GBG78515.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Mlo PF03094.15 GBG78517.1 - 2.1e-116 389.2 3.1 2.6e-116 388.9 3.1 1.0 1 0 0 1 1 1 1 Mlo family Cadherin_C_2 PF16492.5 GBG78517.1 - 1.2 9.9 3.6 3.1 8.6 0.0 3.3 4 1 0 4 4 4 0 Cadherin cytoplasmic C-terminal Ribosomal_S7e PF01251.18 GBG78518.1 - 4.6e-83 277.5 2.8 5.2e-83 277.3 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Herpes_BLRF2 PF05812.12 GBG78518.1 - 0.073 13.2 0.4 0.18 11.9 0.3 1.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein WcbI PF18588.1 GBG78518.1 - 0.098 12.3 0.6 0.34 10.5 0.1 1.8 1 1 1 2 2 2 0 Polysaccharide biosynthesis enzyme WcbI RVT_1 PF00078.27 GBG78519.1 - 1.8e-31 109.4 0.0 2.9e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78519.1 - 3.6e-31 107.2 0.0 4.4e-16 58.7 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78519.1 - 4.3e-30 104.1 0.0 1.2e-29 102.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78519.1 - 2.6e-16 59.4 0.2 5.5e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78519.1 - 6.7e-05 23.0 0.1 0.00022 21.4 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Ribosomal_L34 PF00468.17 GBG78519.1 - 0.088 12.8 0.0 8.5 6.4 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L34 Nop PF01798.18 GBG78520.1 - 8.1e-69 231.6 9.7 2.3e-53 181.0 0.1 3.0 2 1 1 3 3 3 2 snoRNA binding domain, fibrillarin BUD22 PF09073.10 GBG78521.1 - 0.031 13.6 10.3 0.035 13.5 10.3 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG78521.1 - 0.055 12.9 14.2 0.059 12.8 14.2 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 GBG78521.1 - 0.34 10.2 14.3 0.44 9.8 14.3 1.3 1 0 0 1 1 1 0 NOA36 protein Zip PF02535.22 GBG78521.1 - 0.75 9.0 1.8 0.85 8.8 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nucleo_P87 PF07267.11 GBG78521.1 - 0.76 8.6 9.9 0.8 8.5 9.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mpp10 PF04006.12 GBG78521.1 - 1 7.7 15.0 1.3 7.4 15.0 1.1 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 GBG78521.1 - 1.1 9.1 8.3 1.3 8.8 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GBG78521.1 - 1.4 7.1 13.4 1.7 6.8 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 GBG78521.1 - 2 7.3 14.7 2.2 7.2 14.7 1.2 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 GBG78521.1 - 2.3 6.9 4.4 2.3 6.9 4.4 1.1 1 0 0 1 1 1 0 Presenilin TRAP_alpha PF03896.16 GBG78521.1 - 2.9 7.0 7.2 3.6 6.7 7.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DIMCO_N PF16844.5 GBG78523.1 - 0.04 14.2 0.3 5.3 7.4 0.0 3.4 3 1 1 4 4 4 0 Dinitrogenase iron-molybdenum cofactor, N-terminal DLIC PF05783.11 GBG78525.1 - 1.1e-13 50.9 0.0 2.1e-06 26.9 0.0 3.4 4 0 0 4 4 4 2 Dynein light intermediate chain (DLIC) DUF3459 PF11941.8 GBG78525.1 - 0.075 13.4 0.4 0.51 10.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) Myb_DNA-bind_4 PF13837.6 GBG78526.1 - 0.00025 21.3 3.4 0.00031 21.1 2.2 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG78527.1 - 2e-14 53.7 0.0 1.9e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78527.1 - 0.00099 18.9 0.1 0.0023 17.7 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG78528.1 - 4.7e-06 26.3 0.0 1.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG78528.1 - 0.008 16.0 0.0 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG78529.1 - 1.5e-32 112.9 0.0 2.3e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Totivirus_coat PF05518.11 GBG78531.1 - 1.1 7.2 17.2 1.2 7.0 17.2 1.2 1 0 0 1 1 1 0 Totivirus coat protein BUD22 PF09073.10 GBG78531.1 - 4.6 6.5 73.9 0.085 12.2 55.1 2.0 1 1 1 2 2 2 0 BUD22 Red1 PF07964.11 GBG78531.1 - 8.5 4.5 24.4 10 4.2 24.4 1.2 1 0 0 1 1 1 0 Rec10 / Red1 Fe-S_biosyn PF01521.20 GBG78532.1 - 1.1e-14 54.5 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PLAC8 PF04749.17 GBG78533.1 - 2.2e-20 73.5 10.9 2.7e-20 73.2 10.9 1.1 1 0 0 1 1 1 1 PLAC8 family gag-asp_proteas PF13975.6 GBG78534.1 - 9.5e-07 29.3 0.1 2.2e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78534.1 - 4.9e-05 23.9 0.1 0.00012 22.7 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG78534.1 - 0.002 17.9 0.1 0.0034 17.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG78534.1 - 0.06 13.4 2.3 0.14 12.3 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 GBG78534.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease SAICAR_synt PF01259.18 GBG78535.1 - 1.1e-70 238.2 0.0 1.5e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase IMUP PF15761.5 GBG78535.1 - 0.52 11.0 14.0 0.2 12.4 7.9 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Caleosin PF05042.13 GBG78537.1 - 2.1e-73 245.8 0.1 2.5e-73 245.6 0.1 1.0 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 GBG78537.1 - 5.9e-05 22.7 0.1 0.015 15.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GBG78537.1 - 0.0002 21.8 0.0 0.02 15.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GBG78537.1 - 0.0002 21.1 0.3 0.0016 18.2 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GBG78537.1 - 0.0012 18.3 1.1 0.058 13.0 0.2 2.5 2 0 0 2 2 2 1 EF hand LCD1 PF09798.9 GBG78539.1 - 0.12 10.9 0.0 0.12 10.9 0.0 3.1 3 0 0 3 3 3 0 DNA damage checkpoint protein DUF4446 PF14584.6 GBG78540.1 - 0.11 12.5 1.8 0.16 12.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) baeRF_family12 PF18856.1 GBG78540.1 - 2.8 8.5 9.4 1.9 9.1 3.6 2.0 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 TEX19 PF15553.6 GBG78540.1 - 3.1 7.7 9.1 0.55 10.2 4.6 1.7 1 1 1 2 2 2 0 Testis-expressed protein 19 Myb_DNA-bind_4 PF13837.6 GBG78541.1 - 2.3e-07 31.1 4.0 2.3e-07 31.1 4.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG78541.1 - 0.00043 20.5 4.2 0.0021 18.4 1.7 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG78541.1 - 0.037 14.1 0.8 0.084 13.0 0.8 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG78543.1 - 6.7e-32 109.5 0.0 1.3e-15 57.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78543.1 - 1.5e-29 102.3 0.0 3.2e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78543.1 - 1.9e-27 96.2 0.2 3.4e-27 95.4 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3824 PF12868.7 GBG78543.1 - 0.59 10.8 10.3 1.1 10.0 10.3 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3641 PF12345.8 GBG78544.1 - 1.3e-49 167.7 0.0 3e-49 166.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) RVT_1 PF00078.27 GBG78544.1 - 9e-28 97.3 0.2 1.4e-27 96.7 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SLC12 PF03522.15 GBG78545.1 - 1.6e-45 155.9 0.0 1.2e-29 103.7 0.0 2.0 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease PF00324.21 GBG78545.1 - 2.6e-10 39.5 5.4 3.4e-10 39.1 5.4 1.1 1 0 0 1 1 1 1 Amino acid permease NAD_binding_6 PF08030.12 GBG78545.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Phage_sheath_1 PF04984.14 GBG78545.1 - 0.14 12.0 0.1 8.1 6.3 0.1 2.2 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain EI24 PF07264.11 GBG78545.1 - 0.17 12.1 5.1 0.27 11.5 5.1 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) AA_permease PF00324.21 GBG78547.1 - 7.4e-33 113.9 17.1 9.2e-33 113.5 17.1 1.1 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.17 GBG78547.1 - 0.00014 21.3 2.4 0.00031 20.2 2.4 1.6 1 1 0 1 1 1 1 Sodium:alanine symporter family Mis12 PF05859.12 GBG78548.1 - 8.6e-08 32.3 0.2 1.9e-07 31.2 0.2 1.6 1 1 0 1 1 1 1 Mis12 protein DUF2046 PF09755.9 GBG78548.1 - 0.00059 19.2 0.3 0.0011 18.2 0.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Yuri_gagarin PF15934.5 GBG78548.1 - 0.00094 19.1 1.1 0.0016 18.3 1.1 1.4 1 0 0 1 1 1 1 Yuri gagarin Rootletin PF15035.6 GBG78548.1 - 0.011 15.8 1.7 0.017 15.2 1.7 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FUSC PF04632.12 GBG78548.1 - 0.013 14.1 4.2 0.019 13.5 4.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CdvA PF18822.1 GBG78548.1 - 0.022 14.6 1.6 0.058 13.2 0.2 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Spc7 PF08317.11 GBG78548.1 - 0.059 12.2 1.8 0.11 11.4 1.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 GBG78548.1 - 0.1 12.8 6.5 0.054 13.7 4.5 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 GBG78548.1 - 1.2 9.2 3.6 0.61 10.2 0.8 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ZapB PF06005.12 GBG78551.1 - 0.027 14.9 2.1 0.027 14.9 2.1 4.8 3 2 1 4 4 4 0 Cell division protein ZapB ZapB PF06005.12 GBG78552.1 - 0.026 15.0 2.1 0.026 15.0 2.1 4.8 3 2 1 4 4 4 0 Cell division protein ZapB Sod_Cu PF00080.20 GBG78553.1 - 1.7e-10 41.2 0.2 2.4e-08 34.2 0.0 2.6 3 0 0 3 3 3 2 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 GBG78553.1 - 4.7e-05 23.8 0.0 9.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain DDE_Tnp_4 PF13359.6 GBG78554.1 - 1.7e-17 63.5 0.0 2.5e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78554.1 - 1.3e-11 44.5 0.0 2.9e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein RT_RNaseH_2 PF17919.1 GBG78555.1 - 9.4e-13 48.1 0.0 1.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78555.1 - 1.5e-10 41.0 0.1 2.2e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG78555.1 - 0.54 9.6 12.0 0.72 9.2 12.0 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG78555.1 - 1.7 8.3 10.0 2.4 7.9 10.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG78555.1 - 2.2 6.4 12.8 2.8 6.0 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG78555.1 - 3.9 5.7 10.7 5 5.3 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CDC45 PF02724.14 GBG78556.1 - 0.034 12.4 4.6 0.038 12.3 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG78556.1 - 0.52 9.7 12.3 0.7 9.3 12.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG78556.1 - 2.7 6.1 13.6 3.6 5.7 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG78556.1 - 3.9 7.1 11.5 5.3 6.7 11.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein XendoU PF09412.10 GBG78557.1 - 8.3e-86 287.5 0.0 1e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease XendoU Med11 PF10280.9 GBG78558.1 - 1e-07 32.5 0.0 3.2e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Mediator complex protein RNase_P_p30 PF01876.16 GBG78559.1 - 4.2e-05 23.1 0.0 7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 PHD_Oberon PF07227.11 GBG78560.1 - 2.6e-24 85.5 7.2 2.6e-24 85.5 7.2 2.0 2 0 0 2 2 2 1 PHD - plant homeodomain finger protein fn3 PF00041.21 GBG78560.1 - 8.9e-10 38.8 0.1 3.9e-09 36.7 0.1 2.1 1 1 0 1 1 1 1 Fibronectin type III domain zf-HC5HC2H_2 PF13832.6 GBG78560.1 - 3.8e-07 30.2 8.0 1.9e-05 24.8 0.1 2.5 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GBG78560.1 - 1.6e-06 28.3 0.1 1.6e-06 28.3 0.1 2.6 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.29 GBG78560.1 - 0.00026 20.8 4.7 0.00026 20.8 4.7 3.2 3 1 0 3 3 3 2 PHD-finger Pur_ac_phosph_N PF16656.5 GBG78560.1 - 0.088 13.4 0.1 0.45 11.1 0.0 2.2 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain zf-ANAPC11 PF12861.7 GBG78560.1 - 0.14 12.2 1.9 0.4 10.7 1.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SUZ PF12752.7 GBG78560.1 - 0.23 12.3 2.2 1.6 9.5 2.2 2.6 1 0 0 1 1 1 0 SUZ domain RebB PF11747.8 GBG78560.1 - 0.6 10.3 3.9 2.1 8.5 3.9 1.9 1 0 0 1 1 1 0 Killing trait RVT_1 PF00078.27 GBG78561.1 - 1.5e-26 93.3 0.2 2.7e-26 92.5 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78561.1 - 2.3e-22 78.9 0.0 7.1e-22 77.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78561.1 - 4.5e-18 65.5 0.0 1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG78561.1 - 1.9e-06 28.4 0.0 3.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78561.1 - 2.5e-06 28.0 0.0 4.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG78561.1 - 1.4e-05 24.9 0.0 3.8e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG78561.1 - 6.7e-05 22.7 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG78561.1 - 0.016 15.4 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Chromo PF00385.24 GBG78561.1 - 0.024 14.6 0.3 0.046 13.6 0.3 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG78562.1 - 1.9e-05 24.8 0.0 2.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG78562.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Nop53 PF07767.11 GBG78562.1 - 2.3 7.5 16.2 3.2 7.0 16.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Presenilin PF01080.17 GBG78562.1 - 3.5 6.3 4.1 4.6 5.9 4.1 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG78562.1 - 5.3 5.2 11.9 7.2 4.8 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG78562.1 - 8.5 4.4 11.8 11 4.1 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family TAF4 PF05236.14 GBG78563.1 - 0.0041 16.9 8.6 0.0047 16.7 8.6 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family FAM76 PF16046.5 GBG78563.1 - 0.019 14.3 3.4 0.02 14.3 3.4 1.1 1 0 0 1 1 1 0 FAM76 protein eIF3_subunit PF08597.10 GBG78563.1 - 0.14 12.1 11.7 0.13 12.1 11.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4666 PF15697.5 GBG78563.1 - 0.16 12.7 3.6 0.23 12.1 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) Presenilin PF01080.17 GBG78563.1 - 4.2 6.0 5.2 4.3 6.0 5.2 1.1 1 0 0 1 1 1 0 Presenilin PHD_Oberon PF07227.11 GBG78564.1 - 1.9e-15 56.9 12.8 3.4e-15 56.1 12.8 1.4 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein DUF659 PF04937.15 GBG78565.1 - 3.4e-24 85.5 0.1 6.4e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78565.1 - 2e-10 40.3 0.1 5.1e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region EccE PF11203.8 GBG78565.1 - 0.15 12.4 1.0 0.85 10.0 1.0 2.3 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE AT_hook PF02178.19 GBG78565.1 - 5.9 7.1 11.7 5.1 7.3 3.9 3.0 2 0 0 2 2 2 0 AT hook motif fn3 PF00041.21 GBG78566.1 - 7.7e-06 26.2 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain zf-HC5HC2H PF13771.6 GBG78566.1 - 1.3e-05 25.4 4.2 3.3e-05 24.1 4.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.29 GBG78566.1 - 0.00035 20.4 5.2 0.00035 20.4 5.2 1.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 GBG78566.1 - 0.0004 20.5 3.2 0.0004 20.5 3.2 1.8 2 0 0 2 2 2 1 PHD-zinc-finger like domain ADK_lid PF05191.14 GBG78566.1 - 0.01 15.8 0.3 0.03 14.3 0.3 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-RING_2 PF13639.6 GBG78566.1 - 0.097 13.0 4.5 0.26 11.6 4.5 1.8 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 GBG78566.1 - 0.47 10.8 3.0 1.1 9.6 3.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 GBG78566.1 - 1.2 9.2 5.8 0.74 9.8 1.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RanBP PF00641.18 GBG78566.1 - 1.6 8.1 4.8 0.19 11.0 0.2 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PRP38 PF03371.15 GBG78568.1 - 2.6e-60 203.3 0.0 3.2e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Methyltransf_29 PF03141.16 GBG78569.1 - 2.5e-200 666.3 0.0 2.9e-200 666.1 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 GBG78569.1 - 3e-08 34.2 0.0 4e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG78569.1 - 1e-06 29.3 0.0 7.1e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain HDA2-3 PF11496.8 GBG78569.1 - 0.23 10.6 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-bind_4 PF13837.6 GBG78570.1 - 0.0069 16.7 0.7 0.35 11.3 0.1 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG78571.1 - 8.1e-27 93.8 0.0 1.1e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78571.1 - 4.3e-12 46.1 0.0 2e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG78571.1 - 2.2e-05 24.2 0.1 0.00016 21.4 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain Gp45_2 PF17470.2 GBG78572.1 - 0.11 12.5 0.4 3.3 7.7 0.0 3.0 3 0 0 3 3 3 0 Phage gene product 45.2 Histone PF00125.24 GBG78573.1 - 6.9e-09 36.2 0.1 2.2e-08 34.5 0.1 1.9 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Myb_DNA-bind_4 PF13837.6 GBG78574.1 - 4.1e-07 30.3 4.1 8.7e-07 29.2 4.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG78574.1 - 0.0075 16.4 0.8 0.0075 16.4 0.8 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain TilS PF09179.11 GBG78574.1 - 0.0078 16.7 1.6 0.027 15.0 0.1 2.7 3 0 0 3 3 3 1 TilS substrate binding domain Myb_DNA-bind_5 PF13873.6 GBG78574.1 - 0.022 14.8 1.9 0.043 13.9 1.9 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG78574.1 - 0.13 12.6 0.7 0.31 11.4 0.7 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RT_RNaseH_2 PF17919.1 GBG78575.1 - 3.8e-27 94.2 0.0 7.5e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78575.1 - 6.2e-24 84.3 0.0 1.2e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG78575.1 - 5.3e-16 58.7 0.0 2.2e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG78575.1 - 4.5e-07 29.6 0.1 7.5e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plant_tran PF04827.14 GBG78575.1 - 3e-05 23.7 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG78575.1 - 0.0082 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain BSP_II PF05432.11 GBG78575.1 - 0.047 13.4 16.4 0.073 12.8 16.4 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PTPRCAP PF15713.5 GBG78575.1 - 0.57 10.5 13.2 1.4 9.2 13.2 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG78575.1 - 1.3 7.2 9.7 1.3 7.2 8.4 1.5 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 GBG78575.1 - 4.4 5.4 9.6 6.2 4.9 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG78576.1 - 0.15 10.4 13.3 0.19 10.0 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 GBG78576.1 - 5.4 6.2 5.3 7.9 5.7 5.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Nop14 PF04147.12 GBG78576.1 - 7.9 4.6 21.0 11 4.1 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG78576.1 - 8.8 4.3 21.4 12 3.9 21.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG78576.1 - 9.3 5.6 19.8 13 5.1 19.8 1.1 1 0 0 1 1 1 0 SDA1 DUF3219 PF11514.8 GBG78579.1 - 0.072 13.1 0.3 1.4 9.0 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3219) RVT_1 PF00078.27 GBG78580.1 - 7.2e-25 87.8 0.1 1.2e-24 87.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78580.1 - 4.2e-14 52.4 0.0 1e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78580.1 - 0.032 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DTW PF03942.15 GBG78581.1 - 6.7e-19 68.4 0.0 1.3e-18 67.4 0.0 1.4 2 0 0 2 2 2 1 DTW domain RVT_1 PF00078.27 GBG78582.1 - 7.9e-29 100.7 0.0 1.5e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78582.1 - 5.6e-21 74.5 0.0 1.4e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78582.1 - 1.1e-20 73.8 0.0 3.2e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78582.1 - 2.7e-08 33.8 0.7 8.5e-08 32.2 0.5 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain OsmC PF02566.19 GBG78583.1 - 8.3e-17 61.5 0.0 1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein Phage_CRI PF05144.14 GBG78583.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Phage replication protein CRI BORCS8 PF10167.9 GBG78584.1 - 0.04 13.9 0.6 0.096 12.6 0.6 1.6 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 zf-FCS PF06467.14 GBG78584.1 - 0.067 13.1 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif USP8_interact PF08941.10 GBG78584.1 - 0.072 12.9 3.9 0.25 11.1 3.9 1.9 1 0 0 1 1 1 0 USP8 interacting DUF1664 PF07889.12 GBG78584.1 - 0.94 9.5 8.1 0.3 11.1 4.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Pep_deformylase PF01327.21 GBG78584.1 - 3.9 7.1 6.9 0.63 9.6 1.4 2.3 2 0 0 2 2 2 0 Polypeptide deformylase YabA PF06156.13 GBG78584.1 - 9.9 6.9 11.2 16 6.2 6.2 3.5 3 2 0 3 3 3 0 Initiation control protein YabA LCD1 PF09798.9 GBG78585.1 - 2.3 6.7 5.4 2.6 6.5 5.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4666 PF15697.5 GBG78586.1 - 0.052 14.2 1.8 0.068 13.9 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) PspB PF06667.12 GBG78586.1 - 0.09 12.8 2.9 0.19 11.8 2.9 1.7 1 1 0 1 1 1 0 Phage shock protein B Toxin_10 PF05431.11 GBG78586.1 - 0.092 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 eIF3_subunit PF08597.10 GBG78586.1 - 0.45 10.4 13.1 0.48 10.3 13.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 GBG78586.1 - 1.6 7.4 4.6 1.7 7.3 4.6 1.0 1 0 0 1 1 1 0 Presenilin DUF4337 PF14235.6 GBG78586.1 - 3.9 7.6 9.0 4.6 7.3 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) UCH PF00443.29 GBG78587.1 - 1.9 7.9 5.1 2.4 7.6 5.1 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase RVT_1 PF00078.27 GBG78588.1 - 1.6e-07 31.1 0.1 3.1e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_7 PF13499.6 GBG78588.1 - 0.1 13.1 0.1 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair rve PF00665.26 GBG78589.1 - 3.9e-11 43.2 0.0 9.8e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG78589.1 - 3.2e-08 34.1 0.0 5.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78589.1 - 4.6e-08 33.5 0.0 8.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG78589.1 - 3.8e-07 29.9 0.0 8.9e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG78589.1 - 1.6e-06 27.9 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG78590.1 - 1.6e-31 108.3 0.0 4.8e-31 106.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78590.1 - 6.6e-31 106.7 0.1 2.3e-30 105.0 0.1 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78590.1 - 7.7e-25 87.7 0.0 1.5e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78590.1 - 4e-06 26.8 0.0 9.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG78590.1 - 0.0014 18.5 0.0 0.0041 17.0 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Phage_lysozyme PF00959.19 GBG78590.1 - 0.013 15.9 0.2 9 6.8 0.0 3.6 3 0 0 3 3 3 0 Phage lysozyme RasGEF_N PF00618.20 GBG78590.1 - 0.066 13.4 0.0 11 6.3 0.0 2.7 2 0 0 2 2 2 0 RasGEF N-terminal motif RT_RNaseH_2 PF17919.1 GBG78592.1 - 7.9e-34 115.7 0.1 1.5e-33 114.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78592.1 - 2.4e-30 104.9 0.1 5.9e-30 103.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78592.1 - 3.1e-16 59.6 0.1 1.3e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78592.1 - 2.6e-07 30.6 1.9 6.2e-07 29.4 1.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC_6 PF15288.6 GBG78593.1 - 0.014 15.2 1.6 0.042 13.7 1.6 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG78593.1 - 0.03 14.1 0.1 0.049 13.4 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG78594.1 - 2.5e-28 98.0 0.0 2.2e-27 95.0 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78594.1 - 3.9e-28 97.8 0.3 2.4e-27 95.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78594.1 - 0.025 14.1 0.2 0.092 12.2 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG78595.1 - 6.1e-15 55.4 1.8 1.2e-14 54.4 1.8 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG78595.1 - 1.4e-05 25.2 0.2 3e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG78595.1 - 0.0096 16.2 0.4 0.019 15.2 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG78595.1 - 0.061 13.6 1.3 0.14 12.5 0.5 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 GBG78595.1 - 0.081 13.9 0.8 0.19 12.8 0.8 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG78596.1 - 1.4e-38 130.9 0.0 9.7e-24 83.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78596.1 - 7.7e-32 109.7 0.0 2.6e-22 79.1 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78596.1 - 3.5e-26 92.1 0.0 2.3e-22 79.6 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78596.1 - 3.2e-07 30.3 0.0 8.6e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG78596.1 - 0.00012 21.9 0.0 0.00032 20.5 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG78596.1 - 0.025 14.3 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG78596.1 - 0.19 12.1 2.4 0.47 10.8 0.4 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein DUF1917 PF08939.10 GBG78596.1 - 0.37 10.6 4.2 0.4 10.5 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) DUF1682 PF07946.14 GBG78596.1 - 2 7.6 6.1 4 6.6 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RT_RNaseH_2 PF17919.1 GBG78597.1 - 4.2e-25 87.7 0.0 7.7e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78597.1 - 2.5e-23 82.4 0.0 6.1e-23 81.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78597.1 - 0.034 13.6 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG78598.1 - 0.015 15.6 0.2 0.038 14.3 0.2 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF1664 PF07889.12 GBG78598.1 - 0.23 11.5 1.2 4.3 7.4 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DDE_Tnp_4 PF13359.6 GBG78599.1 - 3.1e-31 108.2 0.0 3.4e-30 104.8 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG78599.1 - 6.6e-28 97.7 0.1 1.1e-27 97.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78599.1 - 5.5e-25 87.3 0.0 1.3e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78599.1 - 2.1e-24 85.8 0.0 4.3e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78599.1 - 2.6e-19 69.1 0.2 6.8e-19 67.7 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Plant_tran PF04827.14 GBG78599.1 - 1.2e-14 54.4 0.0 2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein rve PF00665.26 GBG78599.1 - 1.2e-05 25.5 0.1 0.0001 22.5 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain DDE_Tnp_1 PF01609.21 GBG78599.1 - 0.0024 17.6 0.3 0.59 9.7 0.0 2.8 3 0 0 3 3 3 2 Transposase DDE domain zf-H2C2 PF09337.10 GBG78599.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG78601.1 - 6.8e-21 74.6 0.0 1e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78601.1 - 3.9e-07 29.9 0.0 6.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein RVT_1 PF00078.27 GBG78603.1 - 1e-27 97.1 0.1 1.6e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78603.1 - 7.4e-22 77.3 0.0 1.6e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78603.1 - 9.4e-11 41.9 0.0 2.3e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NAAA-beta PF15508.6 GBG78603.1 - 0.14 12.5 0.0 2.2 8.7 0.0 2.7 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase IclR PF01614.18 GBG78604.1 - 1.7 8.5 11.0 0.97 9.3 2.8 2.2 2 0 0 2 2 2 0 Bacterial transcriptional regulator PCEMA1 PF07418.11 GBG78604.1 - 3.4 7.1 16.0 4 6.9 16.0 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 zf-CCHC PF00098.23 GBG78605.1 - 2e-07 30.8 3.5 4.1e-07 29.8 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG78605.1 - 0.0037 16.9 0.9 0.0087 15.7 0.9 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG78605.1 - 0.056 13.2 0.8 0.11 12.2 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Olfactory_mark PF06554.12 GBG78605.1 - 0.19 11.4 2.1 0.44 10.3 2.1 1.5 1 0 0 1 1 1 0 Olfactory marker protein Ribosomal_S3_C PF00189.20 GBG78606.1 - 0.0028 18.1 0.1 0.0053 17.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain RVT_1 PF00078.27 GBG78606.1 - 0.0033 17.0 0.1 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Se-cys_synth_N PF12390.8 GBG78606.1 - 0.058 13.6 1.0 0.13 12.5 0.2 2.2 2 1 0 2 2 2 0 Selenocysteine synthase N terminal Retrotrans_gag PF03732.17 GBG78607.1 - 0.058 13.7 0.1 0.058 13.7 0.1 3.4 4 0 0 4 4 4 0 Retrotransposon gag protein FAM76 PF16046.5 GBG78607.1 - 0.35 10.2 8.0 0.49 9.7 7.2 1.5 2 0 0 2 2 2 0 FAM76 protein DUF5401 PF17380.2 GBG78607.1 - 0.62 8.1 10.4 0.96 7.4 10.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RT_RNaseH_2 PF17919.1 GBG78608.1 - 1e-19 70.4 0.0 2.3e-19 69.3 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78608.1 - 1.1e-11 44.9 0.0 2.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78608.1 - 1.5e-09 37.7 0.0 2.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG78608.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 SlyX PF04102.12 GBG78609.1 - 0.0077 16.8 0.8 0.0077 16.8 0.8 3.5 3 1 0 3 3 3 1 SlyX TRPM_tetra PF16519.5 GBG78609.1 - 0.0089 16.1 2.2 0.5 10.5 0.1 3.2 3 1 0 3 3 3 1 Tetramerisation domain of TRPM DUF2730 PF10805.8 GBG78609.1 - 0.021 14.9 0.6 0.11 12.6 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Retrotrans_gag PF03732.17 GBG78609.1 - 0.067 13.5 1.0 0.25 11.7 0.0 2.4 2 1 0 2 2 2 0 Retrotransposon gag protein Trimer_CC PF08954.11 GBG78609.1 - 0.088 12.4 3.0 0.19 11.3 1.7 2.1 1 1 1 2 2 2 0 Trimerisation motif TolA_bind_tri PF16331.5 GBG78609.1 - 5.7 7.1 16.4 0.081 13.0 5.5 3.0 2 1 1 3 3 3 0 TolA binding protein trimerisation Integrase_H2C2 PF17921.1 GBG78610.1 - 1.2e-14 54.1 0.2 3.9e-14 52.5 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG78610.1 - 1.1e-08 34.9 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sec8_exocyst PF04048.14 GBG78610.1 - 0.06 13.2 0.6 0.16 11.9 0.6 1.7 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 GBG78610.1 - 0.47 10.5 4.4 0.42 10.7 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Bap31_Bap29_C PF18035.1 GBG78610.1 - 3.9 7.6 8.1 0.095 12.7 1.3 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain PIF1 PF05970.14 GBG78611.1 - 1e-72 245.4 0.0 1.6e-72 244.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 GBG78611.1 - 3.7e-08 33.3 0.0 7.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG78611.1 - 0.00098 19.5 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG78611.1 - 0.014 15.8 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RVT_1 PF00078.27 GBG78612.1 - 3.2e-41 141.3 2.8 3.2e-28 98.8 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78612.1 - 5.6e-34 116.2 1.1 2.2e-22 78.9 0.0 3.6 2 1 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78612.1 - 1.2e-28 99.4 1.1 9.1e-16 58.1 0.4 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78612.1 - 1e-17 64.0 0.1 2.7e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78612.1 - 3.2e-14 53.2 0.0 9e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain PUF PF00806.19 GBG78612.1 - 0.011 15.4 0.1 6.3 6.7 0.0 3.0 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat DUF1564 PF07600.11 GBG78612.1 - 0.023 14.4 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG78612.1 - 0.052 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG78612.1 - 0.14 12.7 0.0 1 9.9 0.0 2.5 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease FAM60A PF15396.6 GBG78613.1 - 0.059 13.4 3.4 0.074 13.1 3.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PA26 PF04636.13 GBG78613.1 - 0.15 10.9 6.6 0.18 10.7 6.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF501 PF04417.12 GBG78613.1 - 0.47 10.2 3.9 0.62 9.9 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) PRTP PF01366.18 GBG78613.1 - 0.87 7.6 5.1 1.1 7.2 5.1 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein PSK PF06404.12 GBG78613.1 - 3.4 8.7 10.0 6.3 7.9 10.0 1.5 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) RVT_1 PF00078.27 GBG78614.1 - 3.5e-32 111.7 0.0 6.1e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78614.1 - 6.9e-27 93.4 0.0 1.5e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78614.1 - 4.6e-23 81.5 0.1 1.6e-22 79.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG78614.1 - 0.00023 20.9 0.0 0.00083 19.1 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78614.1 - 0.00057 20.5 0.0 0.0059 17.2 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG78614.1 - 0.00058 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78614.1 - 0.0042 17.6 0.0 0.014 15.9 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2385 PF09539.10 GBG78614.1 - 0.12 13.0 0.6 3.1 8.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) RVT_1 PF00078.27 GBG78615.1 - 4.7e-36 124.4 0.1 7.8e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78615.1 - 5.4e-28 97.0 0.0 1.5e-27 95.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78615.1 - 1.7e-27 95.7 0.0 3.8e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG78615.1 - 3.2e-05 24.5 0.1 6.8e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78615.1 - 5.6e-05 23.6 0.2 0.00018 22.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG78615.1 - 0.00017 21.4 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG78615.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG78615.1 - 0.023 14.5 0.0 0.48 10.2 0.0 2.4 2 1 0 2 2 2 0 Aspartyl protease Phage_GPO PF05929.11 GBG78615.1 - 0.18 11.4 0.1 0.18 11.4 0.1 3.1 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase FAM60A PF15396.6 GBG78615.1 - 1.9 8.5 11.4 0.058 13.4 4.9 1.7 2 0 0 2 2 2 0 Protein Family FAM60A RVT_1 PF00078.27 GBG78617.1 - 5.5e-60 202.6 1.8 4e-29 101.7 0.1 3.4 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78617.1 - 6.2e-38 128.7 1.2 5.3e-18 64.9 0.2 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG78617.1 - 2.8e-31 107.5 0.0 7.4e-31 106.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78617.1 - 8.2e-28 96.8 0.2 1.9e-27 95.6 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78617.1 - 8.1e-25 87.3 0.1 1e-13 51.5 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain RVP_2 PF08284.11 GBG78617.1 - 6.5e-06 26.0 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG78617.1 - 1.3e-05 25.3 0.0 0.43 10.8 0.0 3.3 2 0 0 2 2 2 2 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG78617.1 - 2.8e-05 24.7 0.0 6.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG78617.1 - 0.00091 19.5 0.1 0.065 13.5 0.0 3.3 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG78617.1 - 0.0063 17.0 0.2 0.025 15.2 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG78617.1 - 0.064 13.0 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease Cys_rich_CPXG PF14255.6 GBG78617.1 - 4.9 7.1 5.8 28 4.7 0.4 2.5 2 0 0 2 2 2 0 Cysteine-rich CPXCG Integrase_H2C2 PF17921.1 GBG78618.1 - 5.4e-14 52.0 0.1 1.5e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78618.1 - 2.8e-06 27.5 0.0 6.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG78618.1 - 3.1e-05 23.6 0.0 6.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG78618.1 - 9e-05 23.0 0.0 0.00028 21.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78618.1 - 0.0051 17.4 0.1 0.016 15.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH PF17917.1 GBG78619.1 - 1.9e-27 95.6 0.0 5.4e-27 94.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78619.1 - 9.6e-27 93.0 0.0 2.7e-26 91.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG78619.1 - 1.6e-07 31.1 0.0 3.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78619.1 - 1.8e-06 28.5 0.0 4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78619.1 - 0.00014 22.3 0.0 0.0006 20.3 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG78619.1 - 0.0048 16.7 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG78619.1 - 0.01 15.6 0.0 0.071 12.9 0.0 2.3 2 1 0 2 2 2 0 Aspartyl protease Phage_GPO PF05929.11 GBG78619.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RVP_2 PF08284.11 GBG78620.1 - 2.9e-09 36.8 0.0 5.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG78620.1 - 4.8e-07 29.5 0.1 7.5e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG78620.1 - 1.4e-06 28.9 0.0 3.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78620.1 - 7.3e-06 26.5 0.0 2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG78620.1 - 0.00085 19.6 0.1 0.0022 18.2 0.1 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG78620.1 - 0.0069 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF4187 PF13821.6 GBG78620.1 - 0.014 15.2 0.7 0.037 13.8 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RT_RNaseH_2 PF17919.1 GBG78621.1 - 1e-49 166.7 0.0 1.4e-24 86.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78621.1 - 4e-49 165.3 0.0 4.7e-23 81.5 0.0 3.5 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78621.1 - 9.5e-17 61.2 0.0 7.5e-10 38.7 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78621.1 - 1.7e-13 50.4 0.0 5.1e-13 48.9 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG78621.1 - 0.12 12.7 0.0 0.42 10.9 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein PapC_C PF13953.6 GBG78622.1 - 6.5e-05 22.7 26.3 1.1 9.1 0.3 6.7 1 1 6 7 7 7 4 PapC C-terminal domain Toprim_N PF08275.11 GBG78622.1 - 0.011 15.8 3.2 51 3.9 0.0 4.8 2 1 3 5 5 5 0 DNA primase catalytic core, N-terminal domain SH3_19 PF18597.1 GBG78622.1 - 0.24 11.3 26.6 13 5.7 0.2 6.9 7 0 0 7 7 7 0 Myosin X N-terminal SH3 domain ImpE PF07024.13 GBG78622.1 - 0.25 11.4 8.9 11 6.1 0.1 4.8 2 2 4 6 6 6 0 ImpE protein MU2_FHA PF18221.1 GBG78622.1 - 0.63 10.1 6.8 33 4.6 0.1 4.6 1 1 5 6 6 6 0 Mutator 2 Fork head associated domain RTA1 PF04479.13 GBG78622.1 - 1.3 8.6 5.5 1e+02 2.4 0.0 4.5 2 1 4 6 6 6 0 RTA1 like protein ATP_transf PF09830.9 GBG78622.1 - 9.6 6.4 7.2 16 5.8 0.1 4.2 3 2 2 5 5 5 0 ATP adenylyltransferase rve PF00665.26 GBG78623.1 - 3.1e-14 53.2 0.0 7.3e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78623.1 - 1.5e-11 44.2 0.5 4.5e-11 42.7 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78623.1 - 0.0057 16.8 0.1 0.015 15.5 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_5 PF14787.6 GBG78623.1 - 0.024 14.3 2.4 0.065 13.0 2.4 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PG_binding_4 PF12229.8 GBG78623.1 - 0.082 13.2 0.8 0.27 11.5 0.1 2.1 1 1 1 2 2 2 0 Putative peptidoglycan binding domain ImpA_N PF06812.12 GBG78623.1 - 1.6 8.9 5.3 0.7 10.0 1.2 2.7 2 1 0 2 2 2 0 ImpA, N-terminal, type VI secretion system YabA PF06156.13 GBG78623.1 - 6.6 7.4 9.1 0.74 10.5 2.9 2.5 2 0 0 2 2 2 0 Initiation control protein YabA WDCP PF15390.6 GBG78623.1 - 7.2 4.9 5.8 19 3.5 5.7 1.6 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF3512 PF12024.8 GBG78623.1 - 9 5.7 7.5 2.9 7.3 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) RT_RNaseH_2 PF17919.1 GBG78625.1 - 4.1e-24 84.5 0.0 8.5e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78625.1 - 1e-23 84.0 0.9 1.6e-23 83.4 0.2 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78625.1 - 2.8e-20 72.6 0.0 4.8e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG78626.1 - 0.0067 16.7 0.4 0.036 14.3 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG78626.1 - 0.14 12.0 1.2 0.21 11.4 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG78627.1 - 5.6e-39 132.0 1.5 4e-18 65.3 0.1 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG78627.1 - 2.3e-23 82.5 0.0 7.1e-22 77.7 0.0 2.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78627.1 - 3e-22 78.5 0.0 9.8e-22 76.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78627.1 - 7.1e-16 58.5 0.3 1.9e-08 34.5 0.0 3.5 3 0 0 3 3 3 2 Integrase core domain RVT_1 PF00078.27 GBG78627.1 - 8.9e-08 31.9 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG78627.1 - 5.9e-06 26.4 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG78627.1 - 0.00077 19.7 14.6 0.047 14.0 0.2 4.3 5 0 0 5 5 5 2 Retrotransposon gag protein CARD_2 PF16739.5 GBG78627.1 - 0.015 15.2 0.0 5.3 7.1 0.0 3.2 3 0 0 3 3 3 0 Caspase recruitment domain DUF1664 PF07889.12 GBG78627.1 - 0.68 10.0 2.0 7.8 6.6 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 GBG78629.1 - 0.0019 18.6 17.8 2.4 8.7 0.7 4.6 4 0 0 4 4 4 2 Nucleopolyhedrovirus P10 protein Inhibitor_I29 PF08246.12 GBG78629.1 - 0.0037 17.7 2.4 2.9 8.4 0.2 2.5 2 0 0 2 2 2 2 Cathepsin propeptide inhibitor domain (I29) Retrotrans_gag PF03732.17 GBG78629.1 - 0.0083 16.4 0.0 0.0083 16.4 0.0 5.4 5 0 0 5 5 5 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG78629.1 - 0.066 13.8 47.1 0.12 13.0 6.9 5.2 4 1 1 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 EF-hand_14 PF17959.1 GBG78629.1 - 0.077 13.3 0.6 26 5.3 0.1 3.4 3 0 0 3 3 2 0 EF-hand domain BLOC1_2 PF10046.9 GBG78629.1 - 0.27 11.5 25.2 0.38 11.1 2.8 4.4 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec2p PF06428.11 GBG78629.1 - 0.31 11.0 32.0 11 6.1 3.1 4.4 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p DUF1664 PF07889.12 GBG78629.1 - 0.32 11.0 16.2 10 6.2 0.1 4.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) DASH_Dad3 PF08656.10 GBG78629.1 - 0.37 10.9 8.6 86 3.3 0.0 4.6 4 0 0 4 4 4 0 DASH complex subunit Dad3 Syntaxin-6_N PF09177.11 GBG78629.1 - 0.41 11.2 20.6 4.1 8.0 5.0 4.8 2 2 2 4 4 4 0 Syntaxin 6, N-terminal UPF0449 PF15136.6 GBG78629.1 - 1.3 9.6 25.1 3.4 8.2 0.9 4.7 5 0 0 5 5 4 0 Uncharacterised protein family UPF0449 DUF3552 PF12072.8 GBG78629.1 - 1.4 8.3 31.6 1.5 8.2 20.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1682 PF07946.14 GBG78629.1 - 1.8 7.7 10.9 3.7 6.7 10.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Sas10_Utp3 PF04000.15 GBG78629.1 - 2.7 8.7 11.7 51 4.6 0.1 4.6 4 0 0 4 4 4 0 Sas10/Utp3/C1D family USP8_interact PF08941.10 GBG78629.1 - 3.6 7.4 12.1 8.9 6.1 0.3 4.1 4 0 0 4 4 4 0 USP8 interacting ERM PF00769.19 GBG78629.1 - 7.4 6.3 39.8 0.08 12.7 22.5 2.7 2 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF743 PF05332.11 GBG78631.1 - 0.55 10.3 0.0 0.55 10.3 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF743) DUF4481 PF14800.6 GBG78631.1 - 4 6.8 6.2 6.7 6.1 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) DUF4375 PF14300.6 GBG78631.1 - 6.2 7.1 10.5 5.4 7.3 6.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) SAP PF02037.27 GBG78633.1 - 0.049 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 SAP domain Myb_DNA-bind_4 PF13837.6 GBG78636.1 - 2.4e-07 31.1 2.1 3.4e-07 30.5 2.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG78637.1 - 2.6e-53 180.8 0.5 4.9e-30 104.7 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78637.1 - 2.9e-27 94.6 0.0 6.5e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78637.1 - 3e-17 62.8 0.2 1.3e-13 51.1 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78637.1 - 6.8e-17 61.3 0.1 1.6e-16 60.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78637.1 - 1.5e-14 54.2 0.1 6.6e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG78637.1 - 0.0031 17.7 0.1 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 H2C2 zinc finger DUF5095 PF17016.5 GBG78637.1 - 0.17 11.5 1.5 0.36 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) ZapB PF06005.12 GBG78638.1 - 0.026 14.9 1.8 0.026 14.9 1.8 4.6 4 1 0 4 4 4 0 Cell division protein ZapB RT_RNaseH PF17917.1 GBG78639.1 - 9.8e-26 90.1 0.0 4.3e-25 88.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78639.1 - 4.3e-23 81.3 0.0 9.7e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78639.1 - 1.8e-18 66.4 1.2 4e-18 65.3 1.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78639.1 - 4.8e-17 62.2 0.0 1.4e-16 60.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG78639.1 - 0.074 13.3 0.3 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 H2C2 zinc finger BCL_N PF04714.13 GBG78640.1 - 2.4e-06 27.5 0.4 2.4e-06 27.5 0.4 3.3 3 1 0 3 3 3 1 BCL7, N-terminal conserver region TFIIF_alpha PF05793.12 GBG78640.1 - 0.14 10.7 51.9 0.2 10.2 51.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Caskin-tail PF16632.5 GBG78640.1 - 3.7 8.0 6.8 6.8 7.2 5.3 2.3 1 1 1 2 2 2 0 C-terminal region of Caskin DUF659 PF04937.15 GBG78641.1 - 4e-34 117.7 0.0 9.6e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78641.1 - 0.025 14.4 0.2 0.072 12.9 0.2 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region zf-CCHC PF00098.23 GBG78641.1 - 0.22 11.7 0.8 0.49 10.6 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle HHV6-IE PF03753.13 GBG78641.1 - 2.4 5.5 5.3 4 4.8 5.3 1.2 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein zf-CCHC_6 PF15288.6 GBG78642.1 - 0.041 13.7 0.6 0.13 12.1 0.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG78642.1 - 0.089 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 GBG78642.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG78642.1 - 0.13 12.4 4.1 0.2 11.8 4.1 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG78643.1 - 1.3e-22 80.0 0.0 2.5e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78643.1 - 9.9e-22 76.9 0.0 2.1e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG78643.1 - 0.013 16.0 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF659 PF04937.15 GBG78644.1 - 1.9e-26 92.8 0.0 3.3e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG78644.1 - 0.027 14.5 0.9 0.058 13.4 0.9 1.5 1 0 0 1 1 1 0 BED zinc finger Cwf_Cwc_15 PF04889.12 GBG78646.1 - 0.043 13.6 7.6 0.058 13.1 7.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG78646.1 - 0.1 10.8 11.5 0.11 10.7 11.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG78646.1 - 0.35 10.3 13.7 0.42 10.0 13.7 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 GBG78646.1 - 2.3 7.7 10.5 3.7 7.1 10.5 1.3 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 GBG78646.1 - 2.7 6.2 12.3 3.5 5.8 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG78646.1 - 5.9 6.1 17.9 7.9 5.7 17.9 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 GBG78646.1 - 8.4 5.7 15.4 13 5.1 15.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DOMON PF03351.17 GBG78647.1 - 1.2e-06 28.8 0.1 1.5e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 DOMON domain Retrotrans_gag PF03732.17 GBG78648.1 - 0.0012 19.0 0.0 0.0041 17.3 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein CENP-X PF09415.10 GBG78648.1 - 4.8 7.6 8.5 48 4.4 5.4 3.1 2 1 0 2 2 2 0 CENP-S associating Centromere protein X T4SS_CagC PF16943.5 GBG78649.1 - 0.018 15.2 0.2 0.021 15.0 0.2 1.2 1 1 0 1 1 1 0 Cag pathogenicity island, type IV secretory system PI3_PI4_kinase PF00454.27 GBG78650.1 - 4e-38 131.6 0.0 2.2e-37 129.2 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.23 GBG78650.1 - 0.00018 21.2 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Styelin PF17562.2 GBG78650.1 - 0.087 13.2 0.0 0.31 11.4 0.0 2.0 1 0 0 1 1 1 0 Styelin PAP_PilO PF06864.12 GBG78651.1 - 0.066 12.0 0.7 0.068 12.0 0.7 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) RVT_1 PF00078.27 GBG78653.1 - 2.4e-17 63.2 0.0 4.4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78653.1 - 1.8e-14 53.9 0.0 2.7e-13 50.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78653.1 - 1.5e-07 31.4 1.5 3.2e-07 30.3 0.4 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Myb_DNA-bind_4 PF13837.6 GBG78653.1 - 8.6e-05 22.8 1.4 0.00019 21.8 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG78653.1 - 0.0047 17.0 0.5 0.012 15.7 0.5 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Asp_protease_2 PF13650.6 GBG78653.1 - 0.024 15.3 0.0 0.051 14.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG78653.1 - 0.043 14.0 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF4746 PF15928.5 GBG78653.1 - 1.3 8.4 11.2 2.6 7.4 11.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Integrase_H2C2 PF17921.1 GBG78654.1 - 3.8e-14 52.5 0.1 8.4e-14 51.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78654.1 - 2.3e-07 31.0 0.0 4.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG78654.1 - 0.00011 22.7 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78654.1 - 0.00027 21.5 0.0 0.00054 20.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG78654.1 - 0.0075 16.5 0.0 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease PF09668.10 GBG78654.1 - 0.07 12.9 0.5 0.13 12.1 0.5 1.3 1 0 0 1 1 1 0 Aspartyl protease PTPRCAP PF15713.5 GBG78654.1 - 0.086 13.1 4.4 0.21 11.9 4.4 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RVP PF00077.20 GBG78654.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease PGA2 PF07543.12 GBG78654.1 - 5.9 6.9 9.7 18 5.3 9.7 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 Vps5 PF09325.10 GBG78655.1 - 0.25 10.9 0.1 0.25 10.9 0.1 1.5 2 0 0 2 2 2 0 Vps5 C terminal like Nop14 PF04147.12 GBG78656.1 - 1.7 6.7 34.8 2.1 6.5 34.8 1.2 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 GBG78656.1 - 3.1 6.2 17.0 3.7 6.0 17.0 1.2 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 GBG78656.1 - 4.6 5.2 21.5 4.9 5.2 21.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein F-box-like PF12937.7 GBG78657.1 - 8.1e-06 25.6 0.6 2.4e-05 24.1 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG78657.1 - 4.9e-05 23.1 0.3 0.00012 21.9 0.3 1.6 1 0 0 1 1 1 1 F-box domain VHP PF02209.19 GBG78658.1 - 2.3e-10 40.4 0.1 3.9e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Villin headpiece domain NAD_kinase PF01513.21 GBG78659.1 - 1.5e-55 188.5 0.0 2.4e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GBG78659.1 - 0.0018 17.9 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ASD2 PF08687.11 GBG78659.1 - 2.9 7.4 5.3 0.57 9.7 1.1 1.9 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 NAD_kinase PF01513.21 GBG78660.1 - 6.6e-57 192.9 0.0 1.2e-56 192.1 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GBG78660.1 - 0.0019 17.8 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ASD2 PF08687.11 GBG78660.1 - 2.9 7.4 5.3 0.58 9.7 1.1 1.9 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 PsaA_PsaB PF00223.19 GBG78661.1 - 6.1e-12 44.6 0.2 8.9e-12 44.0 0.2 1.1 1 0 0 1 1 1 1 Photosystem I psaA/psaB protein HSBP1 PF06825.12 GBG78661.1 - 0.92 9.4 7.0 25 4.8 0.4 4.3 4 0 0 4 4 4 0 Heat shock factor binding protein 1 WD40 PF00400.32 GBG78662.1 - 1.2e-23 82.9 9.6 2.5e-06 28.1 0.4 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG78662.1 - 3.8e-07 30.3 2.5 0.039 14.3 0.1 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG78662.1 - 0.0031 16.5 3.1 1.4 7.8 0.6 3.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pex14_N PF04695.13 GBG78662.1 - 0.0036 18.0 18.6 0.0036 18.0 18.6 3.4 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IKI3 PF04762.12 GBG78662.1 - 0.012 13.7 0.0 0.012 13.7 0.0 3.1 4 0 0 4 4 4 0 IKI3 family CCSAP PF15748.5 GBG78662.1 - 0.15 12.2 33.8 0.31 11.2 12.9 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated eIF3_subunit PF08597.10 GBG78662.1 - 0.24 11.3 27.0 0.012 15.6 11.0 3.1 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit TFIIA PF03153.13 GBG78662.1 - 0.48 10.4 78.9 0.097 12.6 35.2 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 GBG78662.1 - 0.82 9.2 28.2 0.19 11.2 13.8 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4407 PF14362.6 GBG78662.1 - 1.3 8.3 36.0 3 7.1 7.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SET PF00856.28 GBG78662.1 - 2.4 8.5 5.5 8.2 6.8 1.7 2.8 2 0 0 2 2 2 0 SET domain XRN_M PF17846.1 GBG78662.1 - 6.7 5.5 15.7 3.2 6.6 8.2 2.2 2 0 0 2 2 2 0 Xrn1 helical domain SAPS PF04499.15 GBG78662.1 - 7.6 5.2 17.5 3 6.5 8.0 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein GramPos_pilinD1 PF16555.5 GBG78662.1 - 7.7 6.7 18.4 6.1 7.0 3.7 2.6 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain WD40 PF00400.32 GBG78663.1 - 1.2e-23 83.0 9.6 2.5e-06 28.1 0.4 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG78663.1 - 3.3e-07 30.5 2.5 0.024 14.9 0.0 4.4 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG78663.1 - 0.0025 16.8 2.9 1.4 7.8 0.6 3.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pex14_N PF04695.13 GBG78663.1 - 0.0036 18.0 18.6 0.0036 18.0 18.6 3.4 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IKI3 PF04762.12 GBG78663.1 - 0.011 13.7 0.0 0.011 13.7 0.0 3.1 4 0 0 4 4 4 0 IKI3 family CCSAP PF15748.5 GBG78663.1 - 0.15 12.2 33.8 0.31 11.2 12.9 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated eIF3_subunit PF08597.10 GBG78663.1 - 0.23 11.3 27.0 0.012 15.6 11.0 3.1 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit TFIIA PF03153.13 GBG78663.1 - 0.59 10.1 79.2 0.14 12.1 35.7 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 GBG78663.1 - 0.79 9.2 28.2 0.19 11.3 13.7 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4407 PF14362.6 GBG78663.1 - 1.3 8.3 36.0 2.9 7.1 7.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SET PF00856.28 GBG78663.1 - 2.4 8.5 5.5 8.1 6.8 1.7 2.8 2 0 0 2 2 2 0 SET domain XRN_M PF17846.1 GBG78663.1 - 6.7 5.5 15.8 3.1 6.6 8.2 2.2 2 0 0 2 2 2 0 Xrn1 helical domain SAPS PF04499.15 GBG78663.1 - 7.5 5.2 17.5 3 6.5 8.0 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF2894 PF11445.8 GBG78663.1 - 8.4 6.8 30.9 1.6 9.2 18.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) WD40 PF00400.32 GBG78664.1 - 1.2e-23 82.9 9.6 2.5e-06 28.1 0.4 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG78664.1 - 3.4e-07 30.5 2.5 0.025 14.9 0.0 4.4 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG78664.1 - 0.0025 16.8 2.9 1.4 7.8 0.6 3.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pex14_N PF04695.13 GBG78664.1 - 0.0036 18.0 18.6 0.0036 18.0 18.6 3.4 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF3_subunit PF08597.10 GBG78664.1 - 0.0082 16.1 10.5 0.0082 16.1 10.5 3.1 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit IKI3 PF04762.12 GBG78664.1 - 0.011 13.7 0.0 0.011 13.7 0.0 3.1 4 0 0 4 4 4 0 IKI3 family CCSAP PF15748.5 GBG78664.1 - 0.15 12.2 33.8 0.31 11.2 12.9 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated TFIIA PF03153.13 GBG78664.1 - 0.47 10.4 78.9 0.097 12.7 35.2 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 GBG78664.1 - 0.82 9.2 28.2 0.19 11.2 13.8 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4407 PF14362.6 GBG78664.1 - 1.3 8.3 36.0 2.9 7.1 7.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SET PF00856.28 GBG78664.1 - 2.4 8.5 5.5 8.2 6.8 1.7 2.8 2 0 0 2 2 2 0 SET domain XRN_M PF17846.1 GBG78664.1 - 6.8 5.5 15.8 3.1 6.6 8.2 2.2 2 0 0 2 2 2 0 Xrn1 helical domain SAPS PF04499.15 GBG78664.1 - 7.6 5.2 17.5 3 6.5 8.0 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein GramPos_pilinD1 PF16555.5 GBG78664.1 - 7.7 6.7 18.4 6.1 7.0 3.7 2.6 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain SlyX PF04102.12 GBG78665.1 - 0.18 12.5 0.1 1.2 9.9 0.2 2.1 2 0 0 2 2 2 0 SlyX PHD PF00628.29 GBG78666.1 - 1.2e-06 28.3 28.0 0.0048 16.8 2.3 3.8 3 0 0 3 3 3 3 PHD-finger DNMT1-RFD PF12047.8 GBG78666.1 - 0.0065 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain PHD_4 PF16866.5 GBG78666.1 - 0.095 12.8 10.5 4.2 7.5 6.1 3.1 1 1 1 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.6 GBG78666.1 - 0.78 10.0 21.9 0.33 11.2 6.7 3.7 1 1 2 3 3 3 0 PHD-like zinc-binding domain PfkB PF00294.24 GBG78668.1 - 5.4e-30 104.7 0.3 4.5e-21 75.4 0.0 3.1 3 1 0 3 3 3 2 pfkB family carbohydrate kinase Ribosomal_L3 PF00297.22 GBG78669.1 - 7.1e-19 68.0 4.3 1.1e-17 64.1 4.0 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Methyltransf_29 PF03141.16 GBG78670.1 - 8.5e-201 667.9 0.0 9.8e-201 667.7 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 GBG78670.1 - 3.4e-08 34.0 0.0 4.9e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GBG78670.1 - 9.3e-07 29.5 0.0 3.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain RT_RNaseH PF17917.1 GBG78671.1 - 2e-18 66.6 0.0 5.7e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78671.1 - 2.7e-17 62.6 0.0 8.6e-17 61.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Porin_3 PF01459.22 GBG78672.1 - 3.4e-58 197.2 5.1 3.9e-58 197.0 5.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin IgG_binding_B PF01378.17 GBG78672.1 - 0.23 11.6 6.6 3.6 7.7 0.2 3.3 3 0 0 3 3 3 0 B domain RVT_1 PF00078.27 GBG78673.1 - 4.2e-31 108.2 0.0 6.4e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78673.1 - 2.4e-29 101.3 0.0 2.2e-15 56.5 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78673.1 - 4.9e-29 100.7 0.0 1.2e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78673.1 - 2.7e-15 56.2 0.0 1.1e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG78673.1 - 2.1e-07 31.1 0.1 7e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG78673.1 - 9.5e-05 22.5 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger UPF0242 PF06785.11 GBG78675.1 - 0.012 15.7 11.7 0.026 14.6 11.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 GBG78675.1 - 0.056 13.0 8.9 0.099 12.2 8.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Med4 PF10018.9 GBG78675.1 - 0.21 11.3 10.0 0.046 13.4 5.4 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF501 PF04417.12 GBG78675.1 - 2.8 7.7 6.4 0.98 9.2 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF501) DUF4404 PF14357.6 GBG78675.1 - 7.8 7.2 10.6 16 6.2 9.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) PAP2 PF01569.21 GBG78676.1 - 5.9e-15 55.2 2.4 5.9e-15 55.2 2.4 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 GBG78676.1 - 0.14 11.8 13.9 0.014 15.1 7.5 2.5 3 0 0 3 3 3 0 PAP2 superfamily PsaL PF02605.15 GBG78677.1 - 1.8e-54 183.5 0.7 2.5e-54 183.0 0.7 1.2 1 0 0 1 1 1 1 Photosystem I reaction centre subunit XI Sep15_SelM PF08806.11 GBG78678.1 - 5.1e-11 42.6 0.0 6.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Sep15/SelM redox domain Thioredoxin_3 PF13192.6 GBG78678.1 - 0.034 14.2 0.2 0.17 12.0 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin domain RVT_1 PF00078.27 GBG78679.1 - 1.4e-33 116.3 0.0 2.5e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG78681.1 - 8.1e-09 35.3 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG78683.1 - 1.7e-36 125.8 0.0 2.6e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG78683.1 - 6e-06 26.9 3.9 8.5e-06 26.4 1.5 2.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 GBG78684.1 - 1.2e-08 34.8 0.0 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FimH_man-bind PF09160.10 GBG78684.1 - 0.21 11.3 0.0 0.54 9.9 0.0 1.6 1 0 0 1 1 1 0 FimH, mannose binding C2 PF00168.30 GBG78685.1 - 5.1e-19 68.5 0.0 1.2e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain gag-asp_proteas PF13975.6 GBG78685.1 - 4.2e-06 27.2 0.0 9.8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78685.1 - 7.6e-05 23.3 0.0 0.00019 22.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG78685.1 - 0.00047 20.3 0.1 0.0009 19.4 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain DUF1758 PF05585.12 GBG78685.1 - 0.0093 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG78685.1 - 0.048 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease CDC45 PF02724.14 GBG78685.1 - 3.5 5.8 13.2 6.4 4.9 13.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG78686.1 - 4.7e-33 114.2 0.3 7.4e-33 113.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) FUSC PF04632.12 GBG78687.1 - 1.9 6.9 5.3 2.2 6.7 4.3 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family LMBR1 PF04791.16 GBG78689.1 - 4.8 6.0 8.8 7.8 5.3 8.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein RVT_1 PF00078.27 GBG78690.1 - 1.1e-30 106.8 0.0 1.4e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG78692.1 - 6e-25 88.1 0.0 8.6e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG78692.1 - 8.6e-07 29.5 0.0 2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78692.1 - 9.9e-07 29.2 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG78692.1 - 2.3e-05 24.1 0.0 4.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG78692.1 - 4.7e-05 23.2 0.0 8.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG78692.1 - 0.016 15.5 0.1 0.059 13.6 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Rtf2 PF04641.12 GBG78693.1 - 4.5 6.6 12.6 24 4.2 9.5 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger NPR3 PF03666.13 GBG78693.1 - 6.9 5.3 10.0 9.4 4.9 10.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF659 PF04937.15 GBG78694.1 - 1.1e-20 74.1 0.0 1.9e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78694.1 - 0.00045 20.0 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG78695.1 - 3.5e-11 43.0 0.1 6e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78695.1 - 2.8e-10 40.1 0.0 1.1e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78695.1 - 0.037 14.3 0.1 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase REV PF00424.18 GBG78695.1 - 0.78 9.8 5.1 1.4 8.9 0.2 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) YrbL-PhoP_reg PF10707.9 GBG78695.1 - 2 7.9 7.2 2.6 7.5 0.9 2.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Phage_lysozyme PF00959.19 GBG78696.1 - 0.025 15.0 0.1 4.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Phage lysozyme DUF3453 PF11935.8 GBG78696.1 - 0.052 13.2 0.5 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3453) RVT_1 PF00078.27 GBG78697.1 - 8.6e-29 100.6 0.1 3.2e-28 98.8 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78697.1 - 1.2e-25 89.4 0.0 3.1e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78697.1 - 4.2e-24 84.9 0.0 1.6e-23 83.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HIP1_clath_bdg PF16515.5 GBG78697.1 - 0.0073 16.9 3.4 0.0073 16.9 3.4 2.6 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Retrotrans_gag PF03732.17 GBG78697.1 - 0.041 14.2 3.7 0.065 13.5 0.0 3.2 3 0 0 3 3 3 0 Retrotransposon gag protein Alpha_Helical PF18489.1 GBG78697.1 - 0.24 11.6 0.9 0.63 10.2 0.9 1.8 1 0 0 1 1 1 0 Alpha helical domain CAP160 PF07918.11 GBG78697.1 - 0.77 9.5 9.8 4.1 7.2 0.1 3.9 3 0 0 3 3 3 0 CAP160 repeat RVT_1 PF00078.27 GBG78698.1 - 8.3e-20 71.3 0.0 9.9e-19 67.7 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG78698.1 - 5.5e-09 36.6 0.0 2.5e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78698.1 - 1e-07 32.4 0.0 6.3e-07 29.9 0.0 2.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG78698.1 - 1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG78698.1 - 0.00025 21.3 11.6 0.0032 17.7 0.1 4.3 4 0 0 4 4 4 2 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG78698.1 - 0.00025 21.0 0.0 0.00084 19.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG78698.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease PaaX_C PF08223.11 GBG78698.1 - 0.0052 17.0 1.0 1 9.7 0.0 3.0 2 0 0 2 2 2 1 PaaX-like protein C-terminal domain HIP1_clath_bdg PF16515.5 GBG78698.1 - 0.018 15.6 3.7 0.018 15.6 3.7 3.5 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tachystatin_A PF11406.8 GBG78701.1 - 0.00022 21.2 2.5 0.27 11.3 0.1 2.3 2 0 0 2 2 2 2 Antimicrobial peptide tachystatin A Invas_SpaK PF03519.14 GBG78701.1 - 0.2 11.8 0.6 25 5.0 0.0 3.3 2 1 1 3 3 3 0 Invasion protein B family Tachystatin_B PF11478.8 GBG78701.1 - 0.22 11.5 1.1 2.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B Annexin PF00191.20 GBG78702.1 - 4.4e-56 186.8 1.5 1.4e-19 69.9 0.1 4.4 4 0 0 4 4 4 4 Annexin SlyX PF04102.12 GBG78702.1 - 0.0096 16.5 0.1 0.0096 16.5 0.1 3.5 3 0 0 3 3 3 1 SlyX DUF3492 PF11997.8 GBG78702.1 - 0.046 13.4 0.3 0.097 12.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) TolA_bind_tri PF16331.5 GBG78702.1 - 0.55 10.4 11.7 0.32 11.1 0.5 3.1 3 0 0 3 3 3 0 TolA binding protein trimerisation TRPM_tetra PF16519.5 GBG78702.1 - 0.56 10.4 3.8 7.5 6.7 0.1 2.9 2 1 0 2 2 2 0 Tetramerisation domain of TRPM Integrase_H2C2 PF17921.1 GBG78703.1 - 1e-50 169.6 3.7 2e-15 56.6 0.0 3.9 3 0 0 3 3 3 3 Integrase zinc binding domain rve PF00665.26 GBG78703.1 - 3.5e-35 120.8 0.4 8.7e-12 45.3 0.0 4.1 3 0 0 3 3 3 3 Integrase core domain RVT_1 PF00078.27 GBG78703.1 - 1.7e-23 83.3 0.2 4.3e-23 82.0 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78703.1 - 2.7e-16 59.7 1.1 4.4e-09 36.6 0.1 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG78703.1 - 3.8e-07 30.2 5.6 0.0041 17.3 0.3 4.7 4 1 0 4 4 4 2 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG78703.1 - 9.4e-07 28.8 0.1 0.0086 16.1 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG78703.1 - 1.2e-06 28.3 0.0 3.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG78703.1 - 0.0029 18.2 0.0 0.015 15.8 0.0 2.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78703.1 - 0.0037 17.9 0.0 0.012 16.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG78703.1 - 0.0046 16.8 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG78703.1 - 0.023 14.5 0.7 0.097 12.5 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) TFIIB PF00382.19 GBG78703.1 - 1.1 9.3 3.4 3.6 7.7 0.2 2.9 3 0 0 3 3 3 0 Transcription factor TFIIB repeat SDA1 PF05285.12 GBG78704.1 - 5.9 6.2 6.4 5.5 6.3 6.4 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG78704.1 - 8.6 4.4 5.6 8 4.5 5.6 1.0 1 0 0 1 1 1 0 Nop14-like family Histone PF00125.24 GBG78705.1 - 2.7e-20 73.0 0.0 6.9e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DAHP_synth_1 PF00793.20 GBG78705.1 - 0.036 12.9 0.0 3.3 6.5 0.0 2.2 2 0 0 2 2 2 0 DAHP synthetase I family Mucin PF01456.17 GBG78706.1 - 6.2 6.8 14.7 8.6 6.3 14.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein RVT_1 PF00078.27 GBG78707.1 - 4.6e-61 206.2 0.4 3.3e-29 102.0 0.1 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78707.1 - 6.1e-59 196.3 0.0 1.8e-33 114.5 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78707.1 - 3.8e-47 158.9 0.1 4e-23 81.7 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78707.1 - 1.4e-18 66.7 0.2 3.5e-18 65.5 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78707.1 - 4.8e-14 52.6 1.0 2.6e-08 34.1 0.0 3.1 3 0 0 3 3 3 2 Integrase core domain Retrotrans_gag PF03732.17 GBG78707.1 - 0.0091 16.3 0.3 0.06 13.6 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG78708.1 - 2.3e-27 96.0 0.1 3.9e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78708.1 - 1.4e-24 86.0 0.0 2.9e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78708.1 - 2.9e-22 78.9 0.0 4.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78708.1 - 1.2e-16 60.5 0.6 5.1e-16 58.5 0.2 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78708.1 - 0.025 14.8 0.1 0.071 13.3 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger TPR_2 PF07719.17 GBG78710.1 - 4.4e-12 45.1 4.5 0.0033 17.4 0.2 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG78710.1 - 6.2e-09 36.0 9.0 0.0072 16.6 1.1 5.8 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG78710.1 - 6.4e-09 35.3 6.6 0.0016 18.2 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG78710.1 - 9.3e-08 31.7 3.4 0.0015 18.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG78710.1 - 1.6e-05 24.7 2.1 0.065 13.5 0.1 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat RT_RNaseH PF17917.1 GBG78710.1 - 1.9e-05 24.9 0.4 4e-05 23.8 0.4 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78710.1 - 3.8e-05 23.9 0.0 9.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain TPR_17 PF13431.6 GBG78710.1 - 0.00019 21.6 1.4 0.98 10.0 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG78710.1 - 0.00052 20.2 0.8 0.14 12.4 0.3 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GBG78710.1 - 0.0014 18.5 0.9 0.82 9.8 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG78710.1 - 0.0034 17.9 1.3 0.59 10.7 0.4 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG78710.1 - 0.0036 17.9 0.6 85 3.9 0.1 5.1 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG78710.1 - 0.005 16.2 4.7 0.11 11.9 0.1 3.3 3 0 0 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 GBG78710.1 - 0.23 12.4 8.3 5 8.2 0.2 6.1 7 1 1 8 8 5 0 Tetratricopeptide repeat Lysis_col PF02402.16 GBG78710.1 - 2.6 7.8 4.9 3.8 7.3 1.4 2.8 1 1 1 2 2 2 0 Lysis protein RVT_1 PF00078.27 GBG78711.1 - 1.2e-24 87.1 0.4 2.3e-24 86.1 0.4 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78711.1 - 3.9e-19 68.6 0.0 1.1e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78711.1 - 8.4e-07 29.2 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Anoct_dimer PF16178.5 GBG78711.1 - 0.05 13.3 5.2 0.14 11.9 1.0 2.7 3 0 0 3 3 3 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin rve PF00665.26 GBG78711.1 - 0.076 13.2 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG78712.1 - 0.0094 16.2 0.2 0.062 13.6 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein CHCH PF06747.13 GBG78713.1 - 1.1e-06 28.6 9.1 1.7e-06 28.0 9.1 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 GBG78713.1 - 0.0025 18.1 5.5 0.0049 17.1 5.5 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 GBG78713.1 - 0.0028 17.3 1.5 0.0043 16.7 1.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CCSAP PF15748.5 GBG78713.1 - 0.0049 17.1 0.3 0.0062 16.7 0.3 1.1 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Cmc1 PF08583.10 GBG78713.1 - 0.024 14.6 6.5 0.093 12.8 6.7 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 GBG78713.1 - 0.21 11.6 5.5 0.53 10.3 5.5 1.7 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 GBG78713.1 - 0.94 9.9 6.5 1.1 9.6 1.4 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GFO_IDH_MocA PF01408.22 GBG78714.1 - 3.1e-20 73.2 0.0 5.5e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 GBG78714.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF659 PF04937.15 GBG78715.1 - 1.3e-14 54.3 0.0 2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78715.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG78716.1 - 6.2e-30 104.4 0.4 1.1e-29 103.5 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78716.1 - 1.6e-24 86.2 0.0 2.7e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78716.1 - 3.1e-19 68.9 0.0 6.3e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78716.1 - 7.3e-13 48.4 0.1 1.5e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG78719.1 - 2.3e-06 27.4 4.1 4.7e-06 26.4 4.1 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG78719.1 - 0.016 14.7 0.0 1.5 8.3 0.0 2.3 1 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_5 PF14787.6 GBG78719.1 - 0.02 14.6 1.4 0.044 13.5 1.4 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG78719.1 - 0.31 10.8 1.0 0.75 9.6 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG78719.1 - 0.49 10.3 1.8 0.98 9.3 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Pkinase_Tyr PF07714.17 GBG78720.1 - 7.4e-43 146.7 0.0 1.3e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG78720.1 - 5e-41 140.8 0.0 7.6e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Malectin_like PF12819.7 GBG78720.1 - 6.9e-11 41.9 0.0 2.1e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Malectin-like domain Malectin PF11721.8 GBG78720.1 - 7.6e-09 35.9 0.0 5.1e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Malectin domain ABC1 PF03109.16 GBG78720.1 - 0.0036 17.4 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 ABC1 family LRR_8 PF13855.6 GBG78720.1 - 0.0046 16.7 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeat RskA PF10099.9 GBG78720.1 - 0.079 13.2 12.3 0.83 9.9 1.4 3.5 4 0 0 4 4 4 0 Anti-sigma-K factor rskA DUF4179 PF13786.6 GBG78720.1 - 0.39 11.2 1.7 11 6.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) BUD22 PF09073.10 GBG78721.1 - 0.046 13.1 15.0 0.069 12.5 15.0 1.3 1 0 0 1 1 1 0 BUD22 Consortin_C PF15281.6 GBG78721.1 - 0.065 13.2 0.2 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 Consortin C-terminus Phage_holin_3_1 PF05106.12 GBG78721.1 - 0.16 12.4 1.1 0.29 11.6 1.1 1.3 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) Band_7 PF01145.25 GBG78722.1 - 6.1e-17 62.2 3.2 9.7e-17 61.5 3.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Macoilin PF09726.9 GBG78722.1 - 0.77 8.2 12.1 1.1 7.8 12.1 1.1 1 0 0 1 1 1 0 Macoilin family Integrase_H2C2 PF17921.1 GBG78723.1 - 8.9e-15 54.6 0.1 2e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-C2H2_10 PF16588.5 GBG78723.1 - 0.025 14.3 0.9 4.2 7.2 0.2 2.6 2 0 0 2 2 2 0 C2H2 zinc-finger KOW PF00467.29 GBG78724.1 - 6.5e-27 92.6 30.9 2.3e-06 27.3 0.3 7.7 7 0 0 7 7 7 5 KOW motif Spt5-NGN PF03439.13 GBG78724.1 - 6.1e-23 80.5 0.2 1.6e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 GBG78724.1 - 0.00041 21.3 16.1 0.00041 21.3 16.1 3.9 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal SH3_13 PF18335.1 GBG78724.1 - 0.15 11.9 0.5 3 7.7 0.3 2.8 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain SH3_15 PF18346.1 GBG78724.1 - 0.16 12.3 1.8 27 5.2 0.0 4.4 4 1 0 4 4 4 0 Mind bomb SH3 repeat domain Rho_N PF07498.12 GBG78725.1 - 0.00036 20.4 0.3 0.00074 19.4 0.3 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 GBG78725.1 - 0.041 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 SAP domain Ribosomal_S3_C PF00189.20 GBG78725.1 - 0.072 13.6 0.5 0.57 10.7 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S3, C-terminal domain Filament PF00038.21 GBG78726.1 - 0.16 11.6 52.7 2.8 7.4 6.6 4.3 1 1 2 4 4 4 0 Intermediate filament protein Lzipper-MIP1 PF14389.6 GBG78726.1 - 1.4 9.3 33.1 1.6 9.0 0.5 6.5 2 2 4 7 7 7 0 Leucine-zipper of ternary complex factor MIP1 Fib_alpha PF08702.10 GBG78726.1 - 1.7 8.8 13.2 7.2 6.8 5.1 3.3 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family CENP-I PF07778.11 GBG78727.1 - 0.79 8.4 5.6 0.97 8.1 5.6 1.2 1 0 0 1 1 1 0 Mis6 Tfb2 PF03849.14 GBG78727.1 - 1.5 7.7 5.7 1.8 7.4 5.7 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 GEN1_C PF18380.1 GBG78727.1 - 9 7.2 18.4 4.1 8.4 9.5 2.2 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain AAA PF00004.29 GBG78728.1 - 3.6e-31 108.3 0.0 5.5e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG78728.1 - 1.9e-08 34.0 1.0 4.5e-08 32.8 1.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain UreF PF01730.16 GBG78729.1 - 5.3e-18 65.9 2.1 8.9e-18 65.2 2.1 1.3 1 0 0 1 1 1 1 UreF TFIID_20kDa PF03847.13 GBG78731.1 - 5.4e-30 103.7 0.1 9.4e-30 102.9 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Integrase_H2C2 PF17921.1 GBG78732.1 - 7.6e-17 61.2 1.1 3.1e-15 56.0 0.6 2.7 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG78732.1 - 1.8e-13 50.6 0.0 5.7e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78732.1 - 7.4e-09 35.4 0.1 1.2e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78732.1 - 2.4e-08 33.9 0.0 7e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG78732.1 - 0.038 14.2 0.2 0.09 13.0 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Cortex-I_coil PF09304.10 GBG78732.1 - 0.054 13.7 2.0 0.13 12.5 2.0 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil K_channel_TID PF07941.11 GBG78732.1 - 4.3 7.9 13.2 8.9 6.9 13.2 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DDA1 PF10172.9 GBG78733.1 - 4.5e-13 49.3 0.0 8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase SAP PF02037.27 GBG78733.1 - 2.2e-09 36.8 2.8 2.2e-09 36.8 2.8 1.8 2 0 0 2 2 2 1 SAP domain Ish1 PF10281.9 GBG78733.1 - 0.03 14.6 0.3 0.061 13.6 0.3 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein HeH PF12949.7 GBG78733.1 - 0.093 12.5 0.8 0.21 11.3 0.8 1.6 1 1 0 1 1 1 0 HeH/LEM domain DDA1 PF10172.9 GBG78734.1 - 4.9e-13 49.1 0.0 8.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase SAP PF02037.27 GBG78734.1 - 7.5e-10 38.3 2.8 2.4e-09 36.7 2.8 1.9 1 0 0 1 1 1 1 SAP domain Ish1 PF10281.9 GBG78734.1 - 0.032 14.5 0.3 0.065 13.5 0.3 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein HeH PF12949.7 GBG78734.1 - 0.096 12.4 0.8 0.22 11.3 0.8 1.6 1 1 0 1 1 1 0 HeH/LEM domain Peptidase_M16_M PF16187.5 GBG78735.1 - 1.1e-76 257.8 0.0 2.9e-41 141.6 0.0 2.4 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GBG78735.1 - 6.9e-35 120.2 1.6 6.3e-34 117.1 0.3 3.0 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GBG78735.1 - 8.3e-26 91.1 0.0 7.1e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain DinB_2 PF12867.7 GBG78735.1 - 0.016 15.7 0.2 0.049 14.1 0.1 1.9 2 0 0 2 2 2 0 DinB superfamily SDA1 PF05285.12 GBG78735.1 - 0.43 10.0 15.0 0.86 9.0 15.0 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG78735.1 - 1.2 8.4 17.4 2.6 7.3 16.1 1.9 2 0 0 2 2 2 0 BUD22 CENP-B_dimeris PF09026.10 GBG78735.1 - 1.2 9.5 26.9 5.6 7.4 0.4 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HEAT_2 PF13646.6 GBG78736.1 - 0.0085 16.5 0.9 0.028 14.8 0.9 1.9 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 GBG78736.1 - 0.033 14.4 0.1 5 7.6 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat Arf PF00025.21 GBG78737.1 - 1.1e-80 269.2 0.2 1.3e-80 269.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GBG78737.1 - 6.9e-14 52.1 0.0 9.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GBG78737.1 - 1.1e-13 51.1 0.0 1.4e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GBG78737.1 - 6.5e-13 48.6 1.7 9.5e-09 34.9 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GBG78737.1 - 9.6e-13 48.0 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GBG78737.1 - 1.4e-10 40.9 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GBG78737.1 - 2e-05 24.6 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GBG78737.1 - 0.0028 17.0 0.6 0.0065 15.8 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase BUD22 PF09073.10 GBG78738.1 - 7.9 5.7 12.3 10 5.4 12.3 1.1 1 0 0 1 1 1 0 BUD22 DUF3395 PF11875.8 GBG78739.1 - 9.6e-25 87.3 0.1 2.1e-24 86.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 GBG78739.1 - 3.7e-20 71.8 1.3 3.7e-20 71.8 1.3 1.9 2 0 0 2 2 2 1 DnaJ domain GSCFA PF08885.11 GBG78739.1 - 0.056 13.1 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 GSCFA family RVT_1 PF00078.27 GBG78740.1 - 2.7e-19 69.6 0.2 5.7e-19 68.5 0.2 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YccV-like PF08755.11 GBG78743.1 - 4.2e-22 78.5 0.0 9.9e-22 77.3 0.0 1.7 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like UVR PF02151.19 GBG78743.1 - 1.7e-05 24.4 15.5 0.00012 21.7 5.8 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif DUF4510 PF14971.6 GBG78743.1 - 0.92 9.8 6.5 2.5 8.4 6.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DUF4140 PF13600.6 GBG78743.1 - 1.4 9.4 7.7 8.8 6.8 1.3 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) GvpL_GvpF PF06386.11 GBG78743.1 - 1.6 8.6 13.3 0.46 10.4 3.2 2.3 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF3509 PF12021.8 GBG78743.1 - 4.3 7.2 5.6 0.49 10.2 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) V_ATPase_I PF01496.19 GBG78744.1 - 3.7 5.4 6.0 4.7 5.0 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Casc1_N PF15927.5 GBG78744.1 - 9.5 5.9 28.7 17 5.0 28.7 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus SDA1 PF05285.12 GBG78745.1 - 3.1 7.2 48.3 3.7 6.9 48.3 1.0 1 0 0 1 1 1 0 SDA1 RNA_polI_A34 PF08208.11 GBG78745.1 - 6.2 6.9 37.4 8.3 6.4 37.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Abhydrolase_6 PF12697.7 GBG78746.1 - 4.6e-06 27.4 0.0 6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family F-box PF00646.33 GBG78747.1 - 1.7e-09 37.3 3.3 4.1e-09 36.1 3.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG78747.1 - 5.8e-06 26.1 2.0 1.5e-05 24.7 2.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG78750.1 - 2.8e-10 39.8 2.6 2.8e-10 39.8 2.6 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GBG78750.1 - 6.1e-08 32.4 2.7 1.2e-07 31.5 2.7 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GBG78750.1 - 0.041 14.3 0.4 0.18 12.3 0.2 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) DUF659 PF04937.15 GBG78751.1 - 9.6e-20 71.0 0.0 1.5e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78751.1 - 2.7e-05 23.8 0.0 5.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF687 PF05095.12 GBG78751.1 - 0.29 9.6 0.6 0.47 8.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF687) RT_RNaseH PF17917.1 GBG78753.1 - 3.5e-13 49.7 0.0 8.6e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78753.1 - 8.4e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78754.1 - 1.7e-16 60.1 0.7 7.3e-16 58.0 0.5 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG78754.1 - 2.7e-13 49.9 0.0 4.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78754.1 - 2.6e-10 40.5 0.0 8.2e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG78754.1 - 1.2e-09 38.4 0.1 2.8e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG78754.1 - 4.5e-05 23.9 0.0 8.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG78754.1 - 4.9e-05 23.1 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78754.1 - 6.8e-05 23.4 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG78754.1 - 0.00048 19.9 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG78754.1 - 0.14 12.2 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Phosphodiest PF01663.22 GBG78755.1 - 1.4e-79 268.3 0.0 1.7e-79 268.0 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GBG78755.1 - 1.2e-09 38.0 0.0 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Sulfatase DUF229 PF02995.17 GBG78755.1 - 0.023 13.3 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 GBG78755.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF1501 PF07394.12 GBG78755.1 - 0.041 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) fn3_3 PF14686.6 GBG78757.1 - 3.7e-09 36.3 0.1 3e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 GBG78757.1 - 9.1e-09 35.4 0.1 1.3e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III DDE_Tnp_4 PF13359.6 GBG78758.1 - 2.3e-08 33.9 0.0 4.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78758.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein rve PF00665.26 GBG78759.1 - 1.2e-17 64.2 0.0 3.4e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78759.1 - 3.9e-17 62.1 0.1 7.9e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG78759.1 - 5.8e-06 26.0 0.0 9.3e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cytotoxic PF09000.10 GBG78759.1 - 0.0063 16.8 4.7 0.82 10.0 0.3 3.7 4 0 0 4 4 4 1 Cytotoxic zf-H2C2 PF09337.10 GBG78759.1 - 0.009 16.2 0.2 0.031 14.5 0.0 2.0 2 0 0 2 2 2 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG78760.1 - 8.3e-20 70.7 0.9 1.8e-19 69.6 0.9 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78760.1 - 3.3e-14 53.1 0.0 1e-13 51.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG78760.1 - 2.2e-07 31.3 0.1 6.1e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78760.1 - 9.1e-06 26.2 0.1 2.3e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG78760.1 - 0.00093 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG78760.1 - 0.012 15.8 0.3 0.027 14.7 0.3 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Topo_Zn_Ribbon PF08272.11 GBG78760.1 - 0.4 10.4 1.8 0.51 10.1 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like DDE_Tnp_4 PF13359.6 GBG78763.1 - 1.2e-28 99.7 0.0 3.4e-28 98.3 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78763.1 - 9.3e-14 51.5 0.0 1.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG78763.1 - 0.0011 18.6 0.3 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG78763.1 - 0.082 13.3 0.1 0.54 10.7 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG78764.1 - 5e-09 36.4 2.5 1.4e-08 35.0 2.5 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG78764.1 - 0.00019 21.6 0.1 0.002 18.3 1.3 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG78764.1 - 0.0014 18.7 0.8 0.0014 18.7 0.8 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG78764.1 - 0.0061 16.8 0.3 0.014 15.7 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG78764.1 - 0.0072 16.4 1.0 0.015 15.3 1.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF2868 PF11067.8 GBG78764.1 - 0.46 9.9 2.3 0.76 9.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF659 PF04937.15 GBG78765.1 - 6.9e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Nop14 PF04147.12 GBG78766.1 - 1.5 6.9 5.6 2.1 6.4 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG78766.1 - 8.1 4.4 8.6 12 3.8 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi MULE PF10551.9 GBG78767.1 - 2.9e-13 50.0 0.0 6.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG78767.1 - 8.5e-08 32.1 1.7 2.3e-07 30.7 0.7 2.1 2 0 0 2 2 2 1 MuDR family transposase DUF3138 PF11336.8 GBG78769.1 - 0.26 9.9 4.0 0.11 11.1 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF755 PF05501.11 GBG78769.1 - 3.1 8.1 12.7 0.86 9.9 6.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RT_RNaseH_2 PF17919.1 GBG78770.1 - 3e-33 113.8 0.0 5.1e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78770.1 - 2.1e-20 73.0 0.0 3.6e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG78772.1 - 1.1e-32 113.0 0.0 1.6e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Lin-8 PF03353.15 GBG78773.1 - 6.1 6.3 8.8 13 5.3 8.8 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Rrn6 PF10214.9 GBG78775.1 - 1.9 6.9 15.0 2.6 6.5 15.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RT_RNaseH_2 PF17919.1 GBG78776.1 - 2.6e-25 88.4 0.0 5.7e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78776.1 - 3.5e-23 81.9 0.0 9.7e-23 80.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78776.1 - 5.1e-07 29.4 0.5 1.1e-06 28.4 0.5 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG78776.1 - 0.0031 16.7 0.3 2.1 7.4 0.0 2.8 2 1 1 3 3 3 2 Autophagy protein Apg17 Retrotrans_gag PF03732.17 GBG78776.1 - 0.011 16.0 0.5 0.011 16.0 0.5 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein LTXXQ PF07813.12 GBG78776.1 - 0.083 13.6 0.0 0.22 12.3 0.0 1.8 1 0 0 1 1 1 0 LTXXQ motif family protein Rrn6 PF10214.9 GBG78777.1 - 2 6.8 4.6 2.6 6.4 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Nop14 PF04147.12 GBG78779.1 - 0.0014 16.9 0.9 0.0016 16.8 0.9 1.3 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.12 GBG78779.1 - 0.0018 17.7 10.3 0.0025 17.2 10.3 1.2 1 0 0 1 1 1 1 NOA36 protein PPP4R2 PF09184.11 GBG78779.1 - 0.01 15.4 5.0 0.012 15.2 5.0 1.1 1 0 0 1 1 1 0 PPP4R2 Voldacs PF03517.13 GBG78779.1 - 0.017 15.2 8.0 0.026 14.6 8.0 1.2 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF3245 PF11595.8 GBG78779.1 - 0.48 10.9 6.6 1.6 9.2 6.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) FAM176 PF14851.6 GBG78779.1 - 0.62 9.7 6.7 1.4 8.6 6.7 1.6 1 0 0 1 1 1 0 FAM176 family RPN2_C PF18004.1 GBG78779.1 - 0.96 9.4 7.0 2.4 8.1 7.0 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2722 PF10846.8 GBG78779.1 - 1 8.3 5.1 1.3 7.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFB6 PF17110.5 GBG78779.1 - 2.7 7.7 5.9 4.3 7.0 5.9 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NPV_P10 PF05531.12 GBG78779.1 - 4.1 7.9 10.1 7.6 7.1 0.8 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Dicty_REP PF05086.12 GBG78779.1 - 8 4.3 7.8 12 3.7 7.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF659 PF04937.15 GBG78781.1 - 1.1e-14 54.6 0.0 2.3e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78781.1 - 0.00022 21.0 0.1 0.001 18.8 0.2 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF2457 PF10446.9 GBG78782.1 - 0.01 15.0 13.3 0.015 14.5 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 GBG78782.1 - 0.015 13.6 10.5 0.02 13.2 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 GBG78782.1 - 0.17 12.2 12.3 0.3 11.3 12.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop53 PF07767.11 GBG78782.1 - 0.29 10.5 12.6 0.4 10.0 12.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.12 GBG78782.1 - 2.9 7.2 15.3 3.8 6.8 15.3 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 GBG78782.1 - 7.4 5.0 8.0 10 4.5 8.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GBG78782.1 - 9 4.4 16.0 12 3.9 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.23 GBG78783.1 - 7.4e-07 29.0 2.4 1.5e-06 28.0 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Peptidase_C101 PF16218.5 GBG78783.1 - 0.1 11.8 1.9 0.22 10.7 1.9 1.5 1 0 0 1 1 1 0 Peptidase family C101 SlyX PF04102.12 GBG78783.1 - 1.4 9.6 13.3 1.9 9.1 0.1 4.8 4 2 0 5 5 5 0 SlyX LPP PF04728.13 GBG78783.1 - 6.1 7.3 10.4 1e+02 3.4 0.0 4.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Fzo_mitofusin PF04799.13 GBG78783.1 - 8.6 5.9 9.8 0.89 9.1 1.1 2.8 2 1 1 3 3 3 0 fzo-like conserved region RNA_polI_A34 PF08208.11 GBG78785.1 - 0.015 15.4 9.3 0.031 14.4 9.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3391 PF11871.8 GBG78785.1 - 0.26 11.8 6.0 0.6 10.7 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Borrelia_P83 PF05262.11 GBG78785.1 - 7.1 5.0 15.7 10 4.5 15.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CSRNP_N PF16019.5 GBG78786.1 - 0.014 15.4 4.5 0.014 15.4 4.5 1.9 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Es2 PF09751.9 GBG78786.1 - 1.8 8.2 17.6 2.5 7.8 17.6 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 FAM60A PF15396.6 GBG78786.1 - 3 7.8 19.8 8.4 6.3 19.8 1.8 1 1 0 1 1 1 0 Protein Family FAM60A AIRC PF00731.20 GBG78787.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 AIR carboxylase Pes-10 PF07149.11 GBG78787.1 - 0.92 8.5 3.4 1.4 7.9 3.4 1.2 1 0 0 1 1 1 0 Pes-10 RT_RNaseH_2 PF17919.1 GBG78788.1 - 4e-32 110.2 0.0 8e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78788.1 - 1.2e-29 102.7 0.1 2.3e-29 101.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78788.1 - 4.2e-24 85.3 0.0 8.9e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78788.1 - 4.8e-20 71.4 0.2 1e-19 70.4 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78788.1 - 1.9e-14 53.9 0.0 4.4e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG78788.1 - 5.7e-06 26.8 0.0 1.4e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78788.1 - 0.00034 21.2 0.0 0.00073 20.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG78788.1 - 0.0027 17.9 0.0 0.0074 16.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG78788.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG78788.1 - 0.033 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG78788.1 - 0.034 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2862 PF11061.8 GBG78788.1 - 0.1 12.5 0.1 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) DUF1904 PF08921.11 GBG78788.1 - 0.16 12.3 0.1 3.9 7.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1904) Cupin_1 PF00190.22 GBG78789.1 - 3.5e-08 33.2 0.0 4.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 GBG78789.1 - 0.00038 20.1 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_8 PF13621.6 GBG78789.1 - 0.068 12.9 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Cupin_4 PF08007.12 GBG78789.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_1 PF00190.22 GBG78790.1 - 3e-08 33.4 0.0 3.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 GBG78790.1 - 0.00057 19.6 0.0 0.00087 19.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_8 PF13621.6 GBG78790.1 - 0.089 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cupin-like domain Epimerase PF01370.21 GBG78791.1 - 4.7e-09 36.1 0.0 7.5e-08 32.1 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GBG78791.1 - 0.00013 21.9 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GBG78791.1 - 0.017 14.6 0.0 0.087 12.2 0.0 2.1 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Glyco_trans_4_4 PF13579.6 GBG78791.1 - 0.053 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Apt1 PF10351.9 GBG78791.1 - 3.6 6.3 5.2 4.7 6.0 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-4CXXC_R1 PF10497.9 GBG78794.1 - 3.3e-26 91.4 13.3 2.2e-25 88.7 13.3 2.1 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF659 PF04937.15 GBG78796.1 - 6.2e-19 68.3 0.2 1.8e-18 66.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG78797.1 - 9.5e-06 25.5 3.5 1.6e-05 24.8 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG78797.1 - 0.0044 16.8 0.4 0.01 15.6 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG78797.1 - 0.04 13.6 0.5 0.082 12.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2362 PF10154.9 GBG78797.1 - 0.061 12.3 10.9 0.078 11.9 10.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) BASP1 PF05466.12 GBG78797.1 - 1.1 9.2 19.5 1.6 8.7 19.5 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) SLC12 PF03522.15 GBG78797.1 - 8 5.4 13.4 9.4 5.1 13.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF659 PF04937.15 GBG78799.1 - 1e-34 119.6 0.5 1.4e-34 119.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG78801.1 - 3.2e-29 100.9 0.0 7.4e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78801.1 - 2.5e-28 98.4 0.7 6.6e-28 97.1 0.1 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG78801.1 - 1.4e-27 96.4 0.0 2.8e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG78801.1 - 5.1e-15 55.3 0.1 1.3e-14 54.0 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Dimer_Tnp_hAT PF05699.14 GBG78801.1 - 4.1e-06 26.5 0.1 1.2e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-H2C2 PF09337.10 GBG78801.1 - 0.00022 21.4 0.0 0.00052 20.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Rhamno_transf PF11316.8 GBG78801.1 - 0.033 13.6 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase SDA1 PF05285.12 GBG78801.1 - 0.56 9.6 6.5 0.9 8.9 6.5 1.2 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 GBG78801.1 - 3.6 7.3 9.9 37 4.0 0.0 2.6 2 0 0 2 2 2 0 FAM176 family RT_RNaseH_2 PF17919.1 GBG78802.1 - 8.4e-30 102.8 0.0 1.4e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78802.1 - 8.8e-30 103.1 0.0 1.5e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PQQ_3 PF13570.6 GBG78802.1 - 0.00024 21.5 1.2 1.1 9.9 0.0 4.3 4 0 0 4 4 4 2 PQQ-like domain NHL PF01436.21 GBG78802.1 - 0.006 16.6 0.5 6.2 7.1 0.0 4.0 3 0 0 3 3 3 1 NHL repeat RVT_1 PF00078.27 GBG78802.1 - 0.01 15.4 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NHL PF01436.21 GBG78803.1 - 0.00057 19.8 1.0 3.6 7.8 0.0 4.4 4 0 0 4 4 4 2 NHL repeat CENP-B_dimeris PF09026.10 GBG78804.1 - 0.0068 16.8 1.4 0.016 15.5 1.4 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RVT_1 PF00078.27 GBG78805.1 - 7.6e-17 61.6 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2201_N PF13203.6 GBG78805.1 - 0.0042 16.7 4.2 0.0042 16.7 4.2 1.6 1 1 0 1 1 1 1 Putative metallopeptidase domain Lin-8 PF03353.15 GBG78805.1 - 0.012 15.2 11.4 0.022 14.3 11.4 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 GBG78805.1 - 0.014 14.9 36.3 0.018 14.5 36.3 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG78805.1 - 0.11 11.8 32.6 0.17 11.2 32.6 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG78805.1 - 0.29 9.3 34.4 0.4 8.8 34.4 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG78805.1 - 3.2 6.4 15.9 4.8 5.9 15.9 1.3 1 0 0 1 1 1 0 Presenilin Integrase_H2C2 PF17921.1 GBG78806.1 - 3.4e-15 55.9 0.0 6.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG78806.1 - 6.2e-07 29.9 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG78806.1 - 3.3e-05 24.0 0.0 5.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG78806.1 - 3.8e-05 24.2 0.0 7.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG78806.1 - 0.037 13.8 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG78806.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG78806.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger DotA PF11388.8 GBG78806.1 - 0.19 11.9 0.0 0.55 10.5 0.0 1.7 2 0 0 2 2 2 0 Phagosome trafficking protein DotA RVT_1 PF00078.27 GBG78807.1 - 4.3e-50 170.3 0.3 5.1e-29 101.4 0.1 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78807.1 - 7e-21 74.1 0.0 1.4e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78807.1 - 5.9e-20 71.5 0.0 2.3e-19 69.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78807.1 - 9.1e-14 51.3 0.0 3e-13 49.7 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78807.1 - 2.2e-09 37.5 0.0 5.9e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG78807.1 - 3.3e-06 27.3 2.6 0.02 15.2 0.2 3.1 2 0 0 2 2 2 2 Retrotransposon gag protein DUF659 PF04937.15 GBG78807.1 - 0.0026 17.6 0.1 0.0079 16.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DUF4187 PF13821.6 GBG78807.1 - 0.028 14.2 0.8 0.098 12.5 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-H2C2 PF09337.10 GBG78807.1 - 0.033 14.4 0.0 0.083 13.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Lipin_mid PF16876.5 GBG78807.1 - 0.076 13.2 0.0 3.6 7.8 0.0 2.8 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Mucin PF01456.17 GBG78808.1 - 7.5 6.5 29.0 15 5.5 29.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein RVT_1 PF00078.27 GBG78809.1 - 7.9e-27 94.2 0.1 1.3e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78809.1 - 3e-22 78.9 0.0 7.7e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78809.1 - 7.6e-17 61.2 0.0 2.4e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78809.1 - 1.8e-15 56.8 1.5 3.8e-15 55.7 1.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG78809.1 - 9.7e-08 32.5 0.0 2.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG78809.1 - 2.7e-07 30.4 0.0 5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78809.1 - 7e-07 29.8 0.0 1.6e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG78809.1 - 5e-05 23.1 0.0 8.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG78809.1 - 0.014 15.5 0.0 0.053 13.7 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG78809.1 - 0.018 15.3 0.1 0.071 13.4 0.1 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein PilZ_2 PF16823.5 GBG78810.1 - 0.041 14.0 0.8 0.26 11.4 0.2 2.2 2 0 0 2 2 2 0 Atypical PilZ domain, cyclic di-GMP receptor Integrase_H2C2 PF17921.1 GBG78811.1 - 7.6e-15 54.8 0.9 5e-14 52.2 0.1 2.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG78811.1 - 7.5e-13 48.7 0.1 1.9e-10 41.0 0.0 3.9 4 0 0 4 4 4 1 Integrase core domain SAWADEE PF16719.5 GBG78811.1 - 1.5e-11 44.5 0.7 1.5e-11 44.5 0.7 2.3 2 0 0 2 2 2 1 SAWADEE domain rve_3 PF13683.6 GBG78811.1 - 0.011 15.5 0.0 5.4 6.9 0.0 3.0 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 GBG78811.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger LcrG PF07216.12 GBG78811.1 - 0.062 13.2 0.6 0.27 11.2 0.6 2.1 1 0 0 1 1 1 0 LcrG protein RPN2_C PF18004.1 GBG78811.1 - 1.5 8.7 7.8 5 7.0 7.8 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RT_RNaseH_2 PF17919.1 GBG78812.1 - 2.1e-55 184.9 0.1 2.6e-31 107.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78812.1 - 1.4e-45 153.9 0.6 1.9e-27 95.6 0.2 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78812.1 - 4.5e-23 81.9 0.0 8.5e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78812.1 - 8.7e-15 54.6 0.0 2.1e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78812.1 - 0.0023 18.1 0.0 0.01 16.1 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG78812.1 - 0.012 15.9 0.9 0.095 13.0 0.1 3.0 2 0 0 2 2 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG78812.1 - 0.093 13.0 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger FAM76 PF16046.5 GBG78812.1 - 1.8 7.9 12.0 3.5 6.9 12.0 1.4 1 0 0 1 1 1 0 FAM76 protein SNF2_N PF00176.23 GBG78813.1 - 1.2e-25 90.0 0.0 2.5e-11 42.9 0.0 3.4 3 0 0 3 3 3 2 SNF2 family N-terminal domain ResIII PF04851.15 GBG78813.1 - 6.3e-10 39.3 0.0 1.7e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GBG78813.1 - 4.4e-09 36.7 0.0 8.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 GBG78813.1 - 7.7e-05 22.5 0.1 0.067 12.9 0.0 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase DEAD PF00270.29 GBG78813.1 - 0.039 13.7 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase NifU PF01106.17 GBG78813.1 - 0.19 11.9 0.7 0.46 10.7 0.7 1.6 1 0 0 1 1 1 0 NifU-like domain AT_hook PF02178.19 GBG78813.1 - 0.28 11.2 32.0 1.5 9.0 4.9 4.9 4 0 0 4 4 4 0 AT hook motif HEPN_RES_NTD1 PF18870.1 GBG78815.1 - 0.077 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 HEAT_EZ PF13513.6 GBG78816.1 - 2.7e-45 152.3 64.7 0.00058 20.3 0.0 26.1 19 7 9 28 28 27 13 HEAT-like repeat HEAT PF02985.22 GBG78816.1 - 6.9e-45 147.2 35.8 0.0068 16.6 0.0 26.3 29 0 0 29 29 28 10 HEAT repeat HEAT_2 PF13646.6 GBG78816.1 - 7.2e-36 122.5 52.4 0.00067 20.0 0.1 20.9 14 4 5 20 20 20 9 HEAT repeats Cnd1 PF12717.7 GBG78816.1 - 1.6e-19 70.6 0.0 0.054 13.5 0.0 10.6 9 2 1 10 10 10 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 GBG78816.1 - 1.4e-15 57.5 0.0 0.0022 17.6 0.0 8.0 7 1 1 8 8 8 2 CLASP N terminal Adaptin_N PF01602.20 GBG78816.1 - 2e-12 46.5 0.0 1.3 7.5 0.1 8.7 6 3 2 9 9 9 3 Adaptin N terminal region MMS19_C PF12460.8 GBG78816.1 - 7.1e-12 45.2 2.0 0.0035 16.5 0.0 8.2 8 1 0 8 8 8 2 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 GBG78816.1 - 7.3e-12 45.7 0.0 2.1 9.0 0.0 10.0 11 2 2 13 13 11 1 Vacuolar 14 Fab1-binding region Gcn1_N PF12074.8 GBG78816.1 - 1.2e-09 37.9 1.4 2.3e-06 27.2 0.0 4.8 5 0 0 5 5 5 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal IFRD PF05004.13 GBG78816.1 - 9e-08 31.6 3.4 0.0065 15.6 0.0 7.4 8 2 1 9 9 9 1 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 GBG78816.1 - 2.9e-05 24.3 0.3 6.6 6.8 0.0 5.8 6 0 0 6 6 6 1 Parkin co-regulated protein NUC173 PF08161.12 GBG78816.1 - 0.00012 21.8 0.0 0.11 12.1 0.0 3.9 2 1 1 3 3 3 1 NUC173 domain DUF3437 PF11919.8 GBG78816.1 - 0.0036 17.2 0.2 6.4 6.8 0.1 5.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) Cohesin_HEAT PF12765.7 GBG78816.1 - 0.004 17.4 4.4 3.9 7.9 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat associated with sister chromatid cohesion Arm PF00514.23 GBG78816.1 - 0.013 15.5 16.3 29 4.9 0.1 11.4 15 0 0 15 15 14 0 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 GBG78816.1 - 0.014 14.6 0.2 24 3.9 0.0 4.8 5 3 2 7 7 7 0 Dopey, N-terminal Proteasom_PSMB PF10508.9 GBG78816.1 - 0.038 12.5 0.0 7.9 4.8 0.0 3.1 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Tti2 PF10521.9 GBG78816.1 - 0.044 13.3 0.1 4.3 6.8 0.0 3.6 3 0 0 3 3 3 0 Tti2 family RTP1_C1 PF10363.9 GBG78816.1 - 0.045 13.9 0.1 3.2e+02 1.5 0.0 6.7 9 1 0 9 9 9 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF937 PF06078.11 GBG78816.1 - 0.076 13.6 10.9 5 7.7 0.1 6.3 6 1 0 6 6 5 0 Bacterial protein of unknown function (DUF937) Ecm29 PF13001.7 GBG78816.1 - 0.079 11.6 5.2 13 4.3 0.4 4.9 5 1 1 6 6 6 0 Proteasome stabiliser ALF PF03752.13 GBG78816.1 - 2.3 8.3 11.3 44 4.2 0.0 6.3 6 0 0 6 6 6 0 Short repeats of unknown function RRM_1 PF00076.22 GBG78818.1 - 7.2e-19 67.4 0.0 1.4e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 GBG78818.1 - 1.5e-18 67.2 1.1 1.5e-18 67.2 1.1 2.7 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_8 PF11835.8 GBG78818.1 - 0.2 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain EAP30 PF04157.16 GBG78819.1 - 1.8e-73 246.7 0.0 2.1e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family ApoC-I PF04691.12 GBG78819.1 - 0.28 11.2 0.4 2.1 8.3 0.0 2.6 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Retrotrans_gag PF03732.17 GBG78820.1 - 0.0059 16.9 0.0 0.0059 16.9 0.0 3.0 4 1 1 5 5 5 1 Retrotransposon gag protein Filo_VP35 PF02097.15 GBG78820.1 - 0.016 14.3 0.4 0.029 13.4 0.4 1.4 1 0 0 1 1 1 0 Filoviridae VP35 FAM76 PF16046.5 GBG78820.1 - 0.3 10.4 7.8 0.49 9.7 7.8 1.2 1 0 0 1 1 1 0 FAM76 protein MRP-S26 PF14943.6 GBG78820.1 - 9.2 6.1 14.3 65 3.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 RT_RNaseH_2 PF17919.1 GBG78822.1 - 7.8e-32 109.3 0.0 1.4e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78822.1 - 4e-28 97.8 0.1 7.7e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78822.1 - 1.7e-16 60.1 0.1 4.2e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG78822.1 - 8.1e-11 41.9 0.2 1.4e-10 41.1 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78822.1 - 2.8e-08 34.0 0.1 1.2e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 GBG78822.1 - 0.055 13.7 0.2 3.6 7.8 0.1 2.8 2 1 1 3 3 3 0 DDE domain RVT_1 PF00078.27 GBG78825.1 - 1.9e-29 102.8 0.1 3e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78825.1 - 1.5e-23 82.7 0.0 3.4e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78825.1 - 2.2e-22 79.3 0.0 3.8e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78825.1 - 5.1e-09 36.1 0.1 5.1e-09 36.1 0.1 3.0 3 0 0 3 3 3 1 Integrase zinc binding domain Integrase_H2C2 PF17921.1 GBG78826.1 - 5.1e-21 74.5 0.2 9.5e-21 73.7 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG78826.1 - 2e-08 34.8 0.0 5.6e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG78826.1 - 1e-07 31.8 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG78826.1 - 8.6e-06 26.2 0.0 2.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG78826.1 - 1.1e-05 25.6 0.0 5.2e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease PF09668.10 GBG78826.1 - 0.0029 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease TolA_bind_tri PF16331.5 GBG78826.1 - 0.061 13.4 3.8 0.18 11.9 3.8 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation Retrotrans_gag PF03732.17 GBG78826.1 - 0.093 13.0 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG78827.1 - 5.1e-13 48.9 0.4 1e-12 47.9 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Jnk-SapK_ap_N PF09744.9 GBG78827.1 - 0.00089 19.5 7.9 0.00089 19.5 7.9 3.2 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 zf-H2C2 PF09337.10 GBG78827.1 - 0.033 14.4 0.9 0.078 13.2 0.9 1.6 1 0 0 1 1 1 0 H2C2 zinc finger CENP-N PF05238.13 GBG78827.1 - 0.14 11.5 2.9 0.31 10.3 2.9 1.6 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Vma12 PF11712.8 GBG78827.1 - 2.3 8.3 6.7 0.45 10.6 0.1 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CENP-N PF05238.13 GBG78828.1 - 1.3 8.2 7.3 1.9 7.7 7.3 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Pox_Ag35 PF03286.14 GBG78828.1 - 4.4 7.0 9.3 9.9 5.9 9.3 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein zf-C3HC4_3 PF13920.6 GBG78829.1 - 1.6e-14 53.5 7.3 2.8e-14 52.7 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 GBG78829.1 - 2.4e-11 44.1 0.0 5.5e-09 36.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GBG78829.1 - 3e-09 37.0 0.0 6e-07 29.6 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GBG78829.1 - 9.9e-09 35.6 0.0 1.1e-05 25.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GBG78829.1 - 3.1e-08 33.7 0.0 0.37 11.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 GBG78829.1 - 1.3e-07 31.3 0.0 0.089 13.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_2 PF13639.6 GBG78829.1 - 6.8e-06 26.3 9.0 1.5e-05 25.2 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GBG78829.1 - 4.4e-05 23.2 10.1 9.9e-05 22.1 10.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GBG78829.1 - 0.00049 19.9 9.2 0.00049 19.9 9.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG78829.1 - 0.001 18.8 10.0 0.0023 17.8 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG78829.1 - 0.0088 16.0 7.9 0.023 14.7 7.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GBG78829.1 - 0.096 12.9 10.3 0.21 11.8 10.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GBG78829.1 - 0.25 11.4 7.9 2 8.5 8.4 2.2 1 1 1 2 2 2 0 RING-type zinc-finger DUF1644 PF07800.12 GBG78829.1 - 2.2 8.3 12.3 1.9 8.6 8.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) zf-B_box PF00643.24 GBG78829.1 - 3 8.1 5.8 6.5 7.0 5.8 1.5 1 0 0 1 1 1 0 B-box zinc finger TerY_C PF15616.6 GBG78829.1 - 9.5 6.3 7.6 21 5.2 7.6 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain DUF659 PF04937.15 GBG78830.1 - 7e-15 55.2 0.0 1.7e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG78831.1 - 1.6e-30 105.1 0.0 3.3e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78831.1 - 4.9e-30 103.9 0.1 1.2e-29 102.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78831.1 - 7.9e-16 57.9 0.1 1.7e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78831.1 - 3.2e-15 56.4 0.0 7.8e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG78831.1 - 0.0059 16.8 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG78831.1 - 0.034 14.1 2.8 0.092 12.7 2.8 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF1564 PF07600.11 GBG78831.1 - 0.042 13.6 0.2 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-CCHC PF00098.23 GBG78831.1 - 2 8.6 4.9 4.9 7.4 4.9 1.7 1 0 0 1 1 1 0 Zinc knuckle RPN13_C PF16550.5 GBG78832.1 - 1e-23 83.6 0.4 2e-23 82.7 0.4 1.4 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 GBG78832.1 - 1.4e-23 83.2 0.0 2.2e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RETICULATA-like PF11891.8 GBG78833.1 - 4.7e-65 218.7 0.1 7.6e-65 218.0 0.1 1.3 1 0 0 1 1 1 1 Protein RETICULATA-related XS PF03468.14 GBG78834.1 - 1e-15 58.0 0.6 2.3e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 XS domain Collagen PF01391.18 GBG78834.1 - 0.83 9.5 4.5 4.8 7.0 4.5 2.3 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Chromo PF00385.24 GBG78836.1 - 2.4e-10 40.2 0.0 4.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG78836.1 - 7.3e-09 35.8 0.0 1.9e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG78837.1 - 0.051 13.7 1.9 0.11 12.6 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Histone PF00125.24 GBG78838.1 - 9.9e-25 87.4 1.1 2.3e-24 86.2 1.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Plavaka PF18759.1 GBG78838.1 - 4.1e-22 78.8 0.0 6.5e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase LCM PF04072.14 GBG78838.1 - 0.038 13.9 0.9 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 Leucine carboxyl methyltransferase DUF1236 PF06823.12 GBG78839.1 - 0.14 12.1 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1236) Plavaka PF18759.1 GBG78840.1 - 1.9e-16 60.2 0.0 2.5e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF2284 PF10050.9 GBG78840.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) RRM_1 PF00076.22 GBG78841.1 - 3.9e-28 97.1 0.0 6.7e-19 67.5 0.1 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG78841.1 - 0.00014 21.9 0.1 0.31 11.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif DUF1866 PF08952.11 GBG78841.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Mito_fiss_reg PF05308.11 GBG78841.1 - 2.2 8.3 7.6 0.42 10.7 2.8 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator RT_RNaseH_2 PF17919.1 GBG78842.1 - 1.9e-23 82.4 0.0 3.7e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78842.1 - 4.6e-22 78.3 0.0 9.6e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG78842.1 - 0.0002 21.9 0.0 0.00056 20.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78842.1 - 0.0011 19.5 0.0 0.0028 18.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG78842.1 - 0.0029 17.9 0.0 0.0086 16.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG78842.1 - 0.0032 17.3 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Na_trans_assoc PF06512.13 GBG78844.1 - 0.026 14.8 2.7 0.032 14.5 2.7 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PI3K_1B_p101 PF10486.9 GBG78844.1 - 1.2 6.9 2.6 1.5 6.5 2.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 GBG78844.1 - 1.3 7.1 9.7 1.6 6.7 9.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4637 PF15470.6 GBG78844.1 - 3.7 7.3 7.8 6.7 6.4 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 GBG78844.1 - 3.7 5.7 5.9 4.7 5.4 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein KIND PF16474.5 GBG78844.1 - 6.1 6.7 9.0 9.4 6.1 9.0 1.2 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Lung_7-TM_R PF06814.13 GBG78845.1 - 6e-06 25.7 5.3 6e-06 25.7 5.3 1.6 2 0 0 2 2 2 1 Lung seven transmembrane receptor UPF0114 PF03350.16 GBG78845.1 - 0.36 11.0 5.4 0.13 12.4 1.3 2.4 3 0 0 3 3 3 0 Uncharacterized protein family, UPF0114 PSI_PSAK PF01241.18 GBG78846.1 - 7.9e-18 64.2 0.2 1.4e-17 63.5 0.2 1.4 1 0 0 1 1 1 1 Photosystem I psaG / psaK HIT PF01230.23 GBG78849.1 - 1.8e-19 70.3 0.0 3.6e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GBG78849.1 - 1.7e-10 41.4 0.0 2.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 GBG78849.1 - 0.0038 17.1 0.1 0.012 15.5 0.1 1.9 1 1 1 2 2 2 1 Protein similar to CwfJ C-terminus 1 GAGA_bind PF06217.12 GBG78849.1 - 9.6 6.4 13.1 16 5.7 13.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Autophagy_act_C PF03987.15 GBG78851.1 - 1.3e-17 64.2 0.2 3.4e-17 62.8 0.2 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 GBG78851.1 - 7.4e-16 57.3 3.3 1.5e-15 56.3 3.3 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal rve PF00665.26 GBG78851.1 - 1.5e-10 41.3 0.0 2.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Autophagy_N PF03986.13 GBG78851.1 - 0.024 14.6 0.0 0.079 12.9 0.0 1.9 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_N PF03986.13 GBG78852.1 - 8.6e-33 113.2 0.3 1.2e-32 112.7 0.3 1.2 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Flavoprotein PF02441.19 GBG78853.1 - 1.9e-45 154.4 0.1 2.2e-45 154.2 0.1 1.0 1 0 0 1 1 1 1 Flavoprotein DDE_Tnp_4 PF13359.6 GBG78854.1 - 3.5e-07 30.0 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG78854.1 - 0.021 14.4 0.0 0.026 14.2 0.0 1.3 1 1 0 1 1 1 0 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG78854.1 - 0.029 14.7 0.3 0.053 13.9 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain Amino_oxidase PF01593.24 GBG78855.1 - 8.8e-13 48.3 2.0 9.3e-09 35.1 0.7 3.1 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG78855.1 - 9.9e-13 48.1 0.6 9.9e-13 48.1 0.6 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG78855.1 - 1.2e-09 38.2 3.9 1.2e-08 34.9 3.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG78855.1 - 6.5e-09 35.4 1.6 6.5e-09 35.4 1.6 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 GBG78855.1 - 3.9e-07 29.8 3.5 1.9e-06 27.5 1.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GBG78855.1 - 1.7e-05 24.2 0.8 0.00027 20.3 0.2 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GBG78855.1 - 3.6e-05 22.6 0.4 0.0016 17.2 1.5 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GBG78855.1 - 0.00031 19.9 3.8 0.0033 16.6 1.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GBG78855.1 - 0.00037 19.8 2.7 0.00037 19.8 2.7 1.8 2 0 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.19 GBG78855.1 - 0.00092 18.7 1.9 0.0017 17.8 0.3 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GBG78855.1 - 0.0011 18.3 0.7 0.0011 18.3 0.7 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4525 PF15027.6 GBG78855.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) MCRA PF06100.11 GBG78855.1 - 0.016 14.1 0.1 0.024 13.4 0.1 1.2 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 GBG78855.1 - 0.017 14.4 0.1 0.031 13.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GBG78855.1 - 0.085 12.1 0.6 0.15 11.3 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GBG78855.1 - 0.11 13.1 4.0 0.078 13.5 0.9 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase_Tyr PF07714.17 GBG78856.1 - 1.1e-42 146.1 0.0 2.4e-42 145.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG78856.1 - 7.6e-42 143.5 0.0 1.4e-41 142.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 GBG78856.1 - 4.1e-05 23.3 0.1 7.7e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat Malectin PF11721.8 GBG78856.1 - 0.00016 21.8 0.0 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 Malectin domain APH PF01636.23 GBG78856.1 - 0.00018 21.5 0.0 0.31 10.9 0.1 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family LRR_1 PF00560.33 GBG78856.1 - 0.00025 21.1 0.5 5 8.1 0.2 4.0 3 0 0 3 3 3 1 Leucine Rich Repeat Malectin_like PF12819.7 GBG78856.1 - 0.00062 19.0 0.0 1.3 8.2 0.0 3.0 3 0 0 3 3 3 2 Malectin-like domain LRR_4 PF12799.7 GBG78856.1 - 0.0015 18.9 0.0 0.0093 16.4 0.2 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) MtN3_slv PF03083.16 GBG78857.1 - 1.6e-35 121.0 15.0 2.8e-18 65.8 2.8 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DAD PF02109.16 GBG78857.1 - 0.012 16.0 2.1 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 DAD family MPC PF03650.13 GBG78857.1 - 0.2 11.8 0.6 16 5.7 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers PQ-loop PF04193.14 GBG78857.1 - 0.45 10.3 6.1 1.4 8.8 0.9 3.2 2 1 1 3 3 3 0 PQ loop repeat Retrotrans_gag PF03732.17 GBG78859.1 - 0.032 14.5 3.0 0.062 13.6 0.1 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG78860.1 - 8.7e-28 97.3 0.1 1.3e-27 96.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78860.1 - 4.7e-24 84.3 0.0 1.3e-23 82.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78860.1 - 4.6e-22 78.3 0.0 7.8e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78860.1 - 4e-17 62.1 1.1 2.7e-16 59.4 0.3 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78860.1 - 0.0021 18.2 0.1 0.006 16.8 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Tyr_Deacylase PF02580.16 GBG78861.1 - 8.7e-50 169.0 0.0 1e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase SNARE PF05739.19 GBG78862.1 - 0.00061 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 SNARE domain DUF4559 PF15112.6 GBG78862.1 - 0.012 15.3 1.3 0.015 15.0 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) K_channel_TID PF07941.11 GBG78862.1 - 0.021 15.3 9.4 0.041 14.3 9.4 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain KxDL PF10241.9 GBG78862.1 - 0.19 12.0 1.3 0.34 11.2 1.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Peptidase_M20 PF01546.28 GBG78863.1 - 1.1e-34 120.0 0.2 1.7e-34 119.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GBG78863.1 - 5e-11 42.5 0.0 1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DnaJ_CXXCXGXG PF00684.19 GBG78864.1 - 2.3 8.7 21.9 0.65 10.4 15.4 3.0 2 2 1 3 3 3 0 DnaJ central domain zf-HIT PF04438.16 GBG78864.1 - 8.9 6.3 8.3 4.6 7.2 1.1 2.7 2 0 0 2 2 2 0 HIT zinc finger RVT_1 PF00078.27 GBG78866.1 - 3.9e-31 108.3 0.7 3.1e-30 105.4 0.1 2.4 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78866.1 - 1.2e-23 83.3 0.0 3e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78866.1 - 2.4e-22 78.8 0.0 6e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Tyr-DNA_phospho PF06087.12 GBG78866.1 - 3.8e-17 62.3 0.0 7.5e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Retrotrans_gag PF03732.17 GBG78866.1 - 1.3e-07 31.8 3.2 0.0034 17.6 0.0 3.8 3 0 0 3 3 3 2 Retrotransposon gag protein RE_AlwI PF09491.10 GBG78867.1 - 0.047 12.5 4.9 0.047 12.5 4.9 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF3629 PF12302.8 GBG78867.1 - 0.082 12.3 7.4 0.1 12.1 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) REV PF00424.18 GBG78867.1 - 0.084 12.9 0.6 0.12 12.4 0.3 1.5 1 1 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Prominin PF05478.11 GBG78867.1 - 0.16 9.9 3.2 0.17 9.8 3.2 1.0 1 0 0 1 1 1 0 Prominin MT PF12777.7 GBG78867.1 - 0.43 9.6 9.3 0.55 9.2 9.3 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor TP53IP5 PF15331.6 GBG78867.1 - 1.6 8.8 12.8 1.7 8.7 12.8 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 UPF0242 PF06785.11 GBG78867.1 - 2 8.5 11.7 2.7 8.1 11.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PA26 PF04636.13 GBG78867.1 - 2.6 6.9 10.0 2.9 6.7 10.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SLC12 PF03522.15 GBG78867.1 - 4.8 6.1 10.9 4.9 6.1 10.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Metal_resist PF13801.6 GBG78867.1 - 5.3 7.3 8.9 1.3 9.3 3.8 2.0 1 1 1 2 2 2 0 Heavy-metal resistance DUF4672 PF15716.5 GBG78867.1 - 5.5 6.6 8.1 6.6 6.3 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) TMPIT PF07851.13 GBG78867.1 - 8.2 5.6 6.8 9.1 5.4 6.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein CCDC85 PF10226.9 GBG78869.1 - 0.0089 15.7 0.1 0.025 14.3 0.1 1.7 1 0 0 1 1 1 1 CCDC85 family HALZ PF02183.18 GBG78869.1 - 0.1 12.8 1.9 0.23 11.7 1.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2385 PF09539.10 GBG78869.1 - 0.14 12.7 0.6 2.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) DivIC PF04977.15 GBG78869.1 - 0.8 9.5 3.4 0.47 10.3 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 GBG78869.1 - 1.2 9.4 4.6 1.1 9.5 1.0 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain bZIP_2 PF07716.15 GBG78869.1 - 1.5 8.9 7.6 0.15 12.2 2.6 2.0 2 0 0 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 GBG78869.1 - 3.7 8.1 5.8 1.6 9.3 2.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 GBG78869.1 - 4.9 7.3 6.7 1.2 9.3 1.7 2.3 2 0 0 2 2 2 0 bZIP transcription factor Retrotrans_gag PF03732.17 GBG78870.1 - 0.00016 21.9 0.1 0.00016 21.9 0.1 3.2 4 0 0 4 4 4 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG78870.1 - 0.0096 15.7 0.7 0.031 14.1 0.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG78870.1 - 0.16 11.3 8.0 0.3 10.4 8.0 1.4 1 0 0 1 1 1 0 FAM76 protein PspB PF06667.12 GBG78870.1 - 2.9 8.0 8.6 19 5.4 0.2 3.0 3 0 0 3 3 3 0 Phage shock protein B RVP_2 PF08284.11 GBG78871.1 - 5.1e-09 36.0 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78871.1 - 1.7e-07 31.8 0.0 7e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78871.1 - 7.1e-06 26.5 0.0 2.4e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SlyX PF04102.12 GBG78871.1 - 0.00075 20.1 12.4 0.0043 17.6 0.3 4.0 4 0 0 4 4 3 1 SlyX Asp_protease PF09668.10 GBG78871.1 - 0.0043 16.8 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG78871.1 - 0.0063 16.8 0.9 0.28 11.5 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2730 PF10805.8 GBG78871.1 - 0.058 13.5 3.6 0.41 10.8 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) CCDC85 PF10226.9 GBG78871.1 - 0.1 12.3 0.1 0.1 12.3 0.1 2.3 2 0 0 2 2 2 0 CCDC85 family DUF1515 PF07439.11 GBG78871.1 - 0.13 12.3 4.6 0.95 9.5 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) CCD48 PF15799.5 GBG78871.1 - 0.15 10.3 12.1 0.038 12.3 2.8 2.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 48 DivIC PF04977.15 GBG78871.1 - 0.15 11.8 8.3 2.8 7.8 1.4 3.0 3 0 0 3 3 3 0 Septum formation initiator YabA PF06156.13 GBG78871.1 - 0.21 12.2 2.4 25 5.6 0.0 3.1 4 0 0 4 4 2 0 Initiation control protein YabA XhlA PF10779.9 GBG78871.1 - 0.23 11.7 2.1 15 5.9 0.1 3.0 2 1 1 3 3 3 0 Haemolysin XhlA DUF16 PF01519.16 GBG78871.1 - 0.51 10.8 0.1 0.51 10.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 bZIP_1 PF00170.21 GBG78871.1 - 0.56 10.3 3.3 2.1 8.5 1.3 2.6 2 1 1 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.15 GBG78871.1 - 0.92 9.6 8.5 1.1 9.4 2.6 2.9 3 0 0 3 3 2 0 Basic region leucine zipper Fez1 PF06818.15 GBG78871.1 - 1.3 9.5 5.2 0.52 10.7 0.7 2.2 2 0 0 2 2 2 0 Fez1 ZapB PF06005.12 GBG78871.1 - 2.1 8.8 7.7 1.8 9.1 0.5 3.2 2 1 0 2 2 2 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 GBG78871.1 - 2.3 8.4 6.3 1.1 9.5 1.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 GBG78871.1 - 5.5 7.3 6.1 10 6.4 1.1 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 GBG78871.1 - 7.1 6.8 9.7 0.99 9.5 1.6 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 GBG78871.1 - 7.9 6.6 6.6 8.1 6.5 0.6 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RVT_1 PF00078.27 GBG78872.1 - 1.4e-24 86.9 0.2 2.3e-24 86.2 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78872.1 - 2.8e-15 56.2 0.0 6e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG78872.1 - 2.3e-06 27.8 0.0 6.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG78872.1 - 2.6e-06 27.2 0.0 4.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78872.1 - 2e-05 25.1 0.0 4.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78872.1 - 2.4e-05 24.8 0.0 6.9e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG78872.1 - 7.3e-05 23.0 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG78872.1 - 0.0022 17.8 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG78873.1 - 2.3e-30 105.8 0.1 4.7e-30 104.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG78873.1 - 5e-09 36.6 0.0 1.6e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78873.1 - 1.9e-08 34.8 0.0 5.5e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG78873.1 - 4.6e-06 26.4 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG78873.1 - 0.00013 21.7 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG78873.1 - 0.0044 17.3 0.2 0.0044 17.3 0.2 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein PapC_C PF13953.6 GBG78875.1 - 0.013 15.3 28.0 0.61 9.9 0.2 8.1 3 2 6 10 10 10 0 PapC C-terminal domain Toprim_N PF08275.11 GBG78875.1 - 0.031 14.3 2.7 64 3.6 0.0 5.8 3 3 4 8 8 8 0 DNA primase catalytic core, N-terminal domain DdrB PF12747.7 GBG78875.1 - 0.73 9.6 18.9 3.6 7.4 0.3 6.2 2 2 3 6 6 6 0 DdrB-like protein gag-asp_proteas PF13975.6 GBG78876.1 - 2.6e-05 24.7 0.0 5.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG78876.1 - 0.00064 20.0 0.1 0.0026 18.0 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG78876.1 - 0.002 17.9 0.0 0.0072 16.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG78876.1 - 0.0049 17.5 0.0 0.014 16.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ACT_3 PF10000.9 GBG78876.1 - 0.049 13.6 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 ACT domain RT_RNaseH_2 PF17919.1 GBG78877.1 - 8.7e-29 99.5 0.0 2e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78877.1 - 2.8e-19 69.0 0.0 4.9e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78877.1 - 7.9e-16 58.3 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG78877.1 - 1.5e-15 57.3 0.0 3.3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG78877.1 - 0.00027 21.1 0.0 0.0006 20.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG78878.1 - 1.8e-30 104.9 0.1 3.6e-30 103.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78878.1 - 1.8e-30 106.1 0.0 3e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78878.1 - 1.6e-19 70.1 0.0 3.4e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_4 PF14392.6 GBG78878.1 - 4.2 7.2 5.4 0.52 10.1 0.0 2.2 2 0 0 2 2 2 0 Zinc knuckle GH-E PF14410.6 GBG78878.1 - 7.9 7.0 7.8 1.4 9.4 1.4 2.9 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Toprim_N PF08275.11 GBG78879.1 - 0.00014 21.9 10.6 21 5.2 0.0 8.4 1 1 9 10 10 10 1 DNA primase catalytic core, N-terminal domain PapC_C PF13953.6 GBG78879.1 - 0.0035 17.1 23.4 3 7.7 0.3 7.7 1 1 6 9 9 9 2 PapC C-terminal domain RTA1 PF04479.13 GBG78879.1 - 0.0043 16.7 11.2 38 3.8 0.0 7.4 5 4 5 10 10 10 0 RTA1 like protein DCR PF14047.6 GBG78879.1 - 0.013 15.7 5.6 74 3.7 0.0 6.3 4 2 4 8 8 8 0 Dppa2/4 conserved region Methyltransf_1N PF02870.15 GBG78879.1 - 0.046 14.5 8.8 1.1e+02 3.8 0.0 6.2 4 2 2 7 7 7 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain ORF_2_N PF18492.1 GBG78879.1 - 0.11 12.6 0.0 55 4.0 0.0 4.3 3 1 2 6 6 6 0 Open reading frame 2 N-terminal domain ImpE PF07024.13 GBG78879.1 - 1.6 8.8 12.8 1.2e+02 2.8 0.1 6.1 5 2 2 8 8 8 0 ImpE protein ATP_transf PF09830.9 GBG78879.1 - 7.9 6.7 15.5 1.7e+02 2.4 0.1 6.8 1 1 6 7 7 7 0 ATP adenylyltransferase rve PF00665.26 GBG78880.1 - 5.1e-15 55.7 0.0 1.2e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78880.1 - 1.7e-10 40.9 0.0 4.5e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG78880.1 - 0.0014 19.2 0.0 0.004 17.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG78880.1 - 0.002 17.9 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 GBG78880.1 - 0.0079 16.0 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG78880.1 - 0.013 15.7 0.1 0.087 13.1 0.1 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG78880.1 - 0.02 14.4 0.0 0.063 12.8 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 GBG78880.1 - 0.075 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78880.1 - 0.083 13.5 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG78880.1 - 0.12 12.2 1.6 0.29 11.0 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle ACT_3 PF10000.9 GBG78880.1 - 0.16 11.9 0.0 0.7 9.8 0.0 2.1 1 0 0 1 1 1 0 ACT domain Toprim_N PF08275.11 GBG78881.1 - 0.00031 20.8 8.0 39 4.3 0.0 7.0 1 1 7 8 8 8 0 DNA primase catalytic core, N-terminal domain Methyltransf_1N PF02870.15 GBG78881.1 - 0.0034 18.2 4.3 32 5.4 0.1 5.0 3 3 1 4 4 4 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain ATP_transf PF09830.9 GBG78881.1 - 0.0053 16.9 7.2 2.5 8.3 0.0 5.3 1 1 5 7 7 7 1 ATP adenylyltransferase ORF_2_N PF18492.1 GBG78881.1 - 0.027 14.6 0.0 23 5.2 0.0 3.5 1 1 1 3 3 3 0 Open reading frame 2 N-terminal domain RTA1 PF04479.13 GBG78881.1 - 0.25 10.9 7.2 65 3.0 0.0 6.0 2 2 7 9 9 9 0 RTA1 like protein DdrB PF12747.7 GBG78881.1 - 1.1 9.1 14.6 24 4.8 0.2 5.2 1 1 5 6 6 6 0 DdrB-like protein tify PF06200.14 GBG78881.1 - 6.2 6.2 13.0 15 5.0 0.1 5.9 7 0 0 7 7 7 0 tify domain Retrotrans_gag PF03732.17 GBG78882.1 - 0.00012 22.3 0.6 1 9.7 0.0 3.5 3 0 0 3 3 3 2 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG78882.1 - 0.0095 16.0 6.2 0.025 14.6 6.2 1.7 1 0 0 1 1 1 1 TolA binding protein trimerisation MAD PF05557.13 GBG78882.1 - 0.026 12.9 1.7 0.043 12.2 1.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF1664 PF07889.12 GBG78882.1 - 0.031 14.3 2.0 0.059 13.4 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YusW PF14039.6 GBG78882.1 - 0.092 13.3 0.6 0.31 11.6 0.5 1.9 2 0 0 2 2 2 0 YusW-like protein ADIP PF11559.8 GBG78882.1 - 0.38 10.8 7.2 0.053 13.6 3.2 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding RVT_1 PF00078.27 GBG78883.1 - 2.8e-29 102.2 0.1 3.9e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78883.1 - 7.7e-10 38.7 0.0 2.5e-09 37.1 0.0 1.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG78883.1 - 0.05 12.7 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH PF17917.1 GBG78883.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Trans_reg_C PF00486.28 GBG78883.1 - 0.14 12.2 0.2 0.39 10.8 0.2 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Integrase_H2C2 PF17921.1 GBG78885.1 - 2.8e-19 69.0 0.3 4.9e-19 68.2 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78885.1 - 1.7e-08 34.7 0.0 6.2e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG78885.1 - 0.00088 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DUF2862 PF11061.8 GBG78885.1 - 0.076 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) Cytochrome_CBB3 PF13442.6 GBG78885.1 - 0.11 12.8 0.2 1.6 9.1 0.0 2.5 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III APG17 PF04108.12 GBG78886.1 - 0.00052 19.3 0.1 0.0011 18.1 0.0 1.5 2 0 0 2 2 2 1 Autophagy protein Apg17 RVT_1 PF00078.27 GBG78886.1 - 0.0031 17.1 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG78886.1 - 0.042 14.1 0.3 0.38 11.0 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein CCDC50_N PF15295.6 GBG78886.1 - 0.45 10.7 4.5 1.1 9.4 4.5 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Prominin PF05478.11 GBG78887.1 - 0.12 10.3 3.7 0.11 10.4 3.7 1.0 1 0 0 1 1 1 0 Prominin MT PF12777.7 GBG78887.1 - 0.46 9.4 9.4 0.54 9.2 9.4 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor RE_AlwI PF09491.10 GBG78887.1 - 0.55 9.0 7.8 0.58 8.9 7.8 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease ANXA2R PF15721.5 GBG78887.1 - 2.6 8.5 6.1 1.4 9.4 2.8 1.7 1 1 1 2 2 2 0 Annexin-2 receptor TP53IP5 PF15331.6 GBG78887.1 - 2.6 8.1 15.6 2.6 8.1 15.6 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Metal_resist PF13801.6 GBG78887.1 - 3.1 8.0 11.5 21 5.3 11.5 2.0 1 1 0 1 1 1 0 Heavy-metal resistance RVT_1 PF00078.27 GBG78889.1 - 2.1e-29 102.6 0.1 3.7e-29 101.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78889.1 - 8.7e-20 70.6 0.0 1.9e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78889.1 - 2.9e-11 43.6 0.0 6.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TFIIF_alpha PF05793.12 GBG78889.1 - 0.00091 17.9 47.8 0.0012 17.5 47.8 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 GBG78889.1 - 0.0091 15.5 48.3 0.016 14.6 48.3 1.4 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG78889.1 - 0.1 10.9 37.3 0.17 10.1 37.3 1.3 1 0 0 1 1 1 0 CDC45-like protein MDM10 PF12519.8 GBG78889.1 - 1.2 7.9 12.8 1.8 7.3 12.8 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 LAP1C PF05609.12 GBG78889.1 - 2.7 7.0 25.1 4.2 6.3 25.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) rve PF00665.26 GBG78890.1 - 9.4e-15 54.8 0.0 2.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG78890.1 - 3e-09 37.3 0.0 1.2e-08 35.4 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78890.1 - 3.6e-06 27.5 0.0 8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG78890.1 - 0.0017 18.2 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 GBG78890.1 - 0.0034 17.5 0.5 0.0071 16.4 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG78890.1 - 0.0074 16.1 0.0 0.018 14.8 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG78890.1 - 0.033 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease PPP4R2 PF09184.11 GBG78890.1 - 2 7.9 13.2 2.8 7.5 13.2 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4140 PF13600.6 GBG78891.1 - 8.3 6.9 8.0 0.86 10.1 0.9 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) RVT_1 PF00078.27 GBG78892.1 - 3.7e-05 23.3 0.5 0.014 14.9 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG78892.1 - 6.1e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG78892.1 - 0.0017 18.9 0.0 0.005 17.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78892.1 - 0.002 18.7 0.0 0.0082 16.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease DUF805 PF05656.14 GBG78894.1 - 0.12 12.8 0.4 0.14 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) zf-CCHC_2 PF13696.6 GBG78895.1 - 0.003 17.4 0.8 0.0047 16.7 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG78895.1 - 0.0058 16.9 0.5 0.019 15.2 0.3 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG78895.1 - 0.13 12.9 0.1 0.31 11.6 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG78895.1 - 0.21 11.7 1.9 0.36 11.0 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG78896.1 - 5.3e-06 26.4 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG78897.1 - 2.9e-33 113.9 0.0 5.3e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78897.1 - 7e-30 103.4 0.0 1.3e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78897.1 - 4.6e-23 81.9 0.3 8.7e-23 81.0 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78897.1 - 3e-16 59.3 0.2 6.8e-16 58.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78897.1 - 8.2e-10 38.9 0.0 2.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HydF_tetramer PF18133.1 GBG78899.1 - 7.7e-35 119.2 0.0 1.5e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 Hydrogen maturase F tetramerization domain RT_RNaseH PF17917.1 GBG78899.1 - 4.1e-27 94.5 0.4 8.9e-27 93.4 0.4 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78899.1 - 2.7e-23 82.6 0.2 6.8e-22 78.1 0.2 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78899.1 - 2.8e-19 69.0 0.0 6.8e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78899.1 - 9.9e-16 57.6 0.0 2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78899.1 - 5.1e-06 26.7 0.3 1.8e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain HydF_dimer PF18128.1 GBG78899.1 - 0.041 13.9 0.3 0.57 10.3 0.0 3.0 3 0 0 3 3 3 0 Hydrogen maturase F dimerization domain K-box PF01486.17 GBG78899.1 - 4.8 7.4 11.0 0.39 10.9 1.6 3.4 4 0 0 4 4 4 0 K-box region RT_RNaseH_2 PF17919.1 GBG78901.1 - 7.1e-24 83.7 0.0 1.5e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78901.1 - 2.2e-22 79.3 0.0 4.6e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78901.1 - 3.4e-17 62.7 0.0 4.8e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG78901.1 - 0.069 12.2 0.1 0.17 11.0 0.0 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG78902.1 - 4.7e-31 106.8 0.0 3.1e-30 104.2 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78902.1 - 6e-23 81.1 0.0 1.6e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78902.1 - 8.9e-14 51.5 0.1 5.2e-11 42.5 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG78902.1 - 4.5e-06 26.5 0.0 9.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG78902.1 - 0.001 19.7 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78902.1 - 0.11 13.1 0.0 0.33 11.6 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF659 PF04937.15 GBG78903.1 - 5.4e-28 97.8 0.1 9.3e-28 97.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78903.1 - 2.6e-09 36.8 0.1 5.8e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG78904.1 - 6.5e-09 35.8 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG78907.1 - 2e-27 96.1 0.1 3.5e-27 95.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78907.1 - 6.2e-23 80.7 0.0 1.9e-22 79.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78907.1 - 2.6e-15 56.6 0.0 7.7e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG78907.1 - 7.9e-06 26.4 0.0 9.4e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78907.1 - 1.4e-05 25.6 0.0 7.4e-05 23.2 0.0 2.3 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG78907.1 - 0.00012 22.3 0.8 0.0017 18.6 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG78907.1 - 0.00037 20.3 0.0 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG78907.1 - 0.00076 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Lys-AminoMut_A PF09043.11 GBG78907.1 - 0.39 9.1 0.6 0.61 8.5 0.6 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit HXXSHH PF07586.11 GBG78907.1 - 0.57 9.7 3.0 14 5.1 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) DUF4404 PF14357.6 GBG78907.1 - 4.4 8.0 7.1 0.48 11.1 0.7 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4404) RT_RNaseH_2 PF17919.1 GBG78909.1 - 1.3e-24 86.1 0.0 3e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78909.1 - 5.2e-22 78.1 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78909.1 - 3.6e-14 52.6 2.2 1.4e-13 50.8 0.2 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG78909.1 - 1.1e-09 38.1 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78909.1 - 4e-09 36.7 0.0 1.1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrin_b_cyt PF08725.11 GBG78909.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RVT_1 PF00078.27 GBG78910.1 - 6e-21 75.0 0.2 3e-20 72.7 0.1 2.1 1 1 2 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78910.1 - 2.9e-12 46.5 0.9 8.4e-12 45.0 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG78910.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF5095 PF17016.5 GBG78910.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) DUF1758 PF05585.12 GBG78910.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Retrotrans_gag PF03732.17 GBG78911.1 - 0.00044 20.5 1.1 0.00097 19.4 0.2 2.1 2 1 1 3 3 3 1 Retrotransposon gag protein Lys-AminoMut_A PF09043.11 GBG78911.1 - 0.076 11.5 0.6 0.11 10.9 0.6 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit DUF4211 PF13926.6 GBG78911.1 - 0.31 11.1 2.2 2 8.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) RT_RNaseH_2 PF17919.1 GBG78912.1 - 5.2e-45 151.6 0.0 6.2e-22 77.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78912.1 - 5e-40 136.0 0.0 8.9e-19 67.7 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78912.1 - 1.5e-30 106.3 0.2 3.6e-18 65.9 0.0 3.5 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78912.1 - 6.3e-15 55.0 1.1 8.5e-15 54.6 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG78912.1 - 3.2e-09 37.0 0.0 8.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 GBG78913.1 - 3.4e-16 59.5 0.0 7.7e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain PLD_C PF12357.8 GBG78913.1 - 0.039 13.9 1.2 13 5.8 0.1 2.9 3 0 0 3 3 3 0 Phospholipase D C terminal Tachylectin PF14517.6 GBG78913.1 - 0.048 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Tachylectin rve PF00665.26 GBG78914.1 - 1.2e-06 28.7 0.0 2.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG78914.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG78914.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG78914.1 - 0.022 15.0 0.0 0.065 13.5 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein RAP1 PF07218.11 GBG78914.1 - 0.14 10.4 3.1 0.21 9.9 3.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S64 PF08192.11 GBG78914.1 - 0.22 10.0 1.5 0.33 9.4 1.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Miga PF10265.9 GBG78914.1 - 1.3 7.9 4.3 2 7.3 4.3 1.2 1 0 0 1 1 1 0 Mitoguardin Retrotrans_gag PF03732.17 GBG78915.1 - 0.0077 16.5 1.0 0.016 15.5 0.0 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG78916.1 - 1.6e-32 111.5 0.0 3.4e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78916.1 - 1.1e-28 100.3 0.2 2.1e-28 99.4 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78916.1 - 2.5e-28 98.4 0.2 5.3e-28 97.4 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78916.1 - 2.5e-17 62.7 0.5 6.4e-17 61.4 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG78916.1 - 7.9e-13 48.6 0.0 2.2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG78916.1 - 9e-05 22.6 0.0 0.0005 20.2 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger DUF1564 PF07600.11 GBG78916.1 - 0.0075 16.0 0.4 0.03 14.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) CotJB PF12652.7 GBG78916.1 - 0.43 10.8 2.7 56 4.1 0.0 3.8 4 0 0 4 4 4 0 CotJB protein RT_RNaseH_2 PF17919.1 GBG78917.1 - 1.4e-32 111.7 0.0 4.4e-32 110.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78917.1 - 2.2e-31 109.1 0.5 1.3e-30 106.6 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78917.1 - 4.2e-19 68.8 0.0 1.4e-18 67.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG78917.1 - 1.7e-06 28.5 0.0 5.9e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78917.1 - 0.00044 20.8 0.0 0.0017 18.9 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG78917.1 - 0.0014 18.8 0.1 0.99 9.7 0.0 2.8 2 0 0 2 2 2 2 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG78917.1 - 0.0028 17.7 0.1 0.0062 16.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG78917.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG78917.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Integrase_H2C2 PF17921.1 GBG78918.1 - 3.4e-18 65.5 0.6 7.6e-18 64.4 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG78918.1 - 1.9e-17 63.5 0.0 3.6e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78918.1 - 2e-11 43.8 0.0 4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrin_b_cyt PF08725.11 GBG78918.1 - 0.046 13.4 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RT_RNaseH_2 PF17919.1 GBG78919.1 - 1.3e-33 115.0 0.1 5.7e-33 112.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78919.1 - 7.9e-29 100.0 0.0 2.9e-28 98.2 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78919.1 - 1.8e-28 99.6 0.1 3.7e-28 98.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78919.1 - 0.00065 19.9 0.1 0.0033 17.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain TetR_C_15 PF17918.1 GBG78919.1 - 0.046 14.5 0.3 0.4 11.5 0.3 2.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RT_RNaseH_2 PF17919.1 GBG78920.1 - 1.6e-74 246.3 0.0 5.6e-34 116.2 0.1 3.5 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78920.1 - 2e-52 175.9 0.3 1.1e-30 105.9 0.1 3.6 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78920.1 - 3.4e-18 66.0 7.4 7.3e-09 35.5 0.1 4.6 3 1 1 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78920.1 - 3.7e-17 62.6 0.1 1.7e-16 60.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Radical_SAM PF04055.21 GBG78920.1 - 7.8e-12 45.9 1.0 2.6e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 Radical SAM superfamily REV PF00424.18 GBG78920.1 - 5.4 7.1 7.9 4.7 7.3 0.1 3.4 4 0 0 4 4 4 0 REV protein (anti-repression trans-activator protein) rve PF00665.26 GBG78921.1 - 5.1e-11 42.8 0.0 1.9e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78921.1 - 0.34 11.0 1.3 0.63 10.2 1.3 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain rve PF00665.26 GBG78922.1 - 2.5e-15 56.7 0.0 6.7e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78922.1 - 9.7e-09 35.2 0.5 2e-08 34.2 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG78922.1 - 0.0079 15.9 0.0 0.071 12.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Chromo PF00385.24 GBG78922.1 - 0.011 15.7 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF659 PF04937.15 GBG78923.1 - 2.8e-31 108.4 0.0 4.8e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78923.1 - 0.00064 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG78924.1 - 7.3e-17 61.6 0.0 3.8e-15 56.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78924.1 - 0.00046 19.9 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RRM_1 PF00076.22 GBG78925.1 - 7.1e-22 77.0 0.1 1e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG78925.1 - 0.0035 17.4 0.0 0.006 16.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 GBG78925.1 - 0.0035 16.9 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG78925.1 - 0.0099 15.7 0.0 0.021 14.7 0.0 1.6 1 1 0 1 1 1 1 Occluded RNA-recognition motif DUF4944 PF16302.5 GBG78925.1 - 0.055 13.5 0.0 0.069 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) AAR2 PF05282.11 GBG78926.1 - 3.5e-84 283.2 0.0 5.1e-84 282.7 0.0 1.3 1 0 0 1 1 1 1 AAR2 protein NdhS PF11623.8 GBG78927.1 - 2.3e-28 97.6 0.0 3.5e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H dehydrogenase subunit S RVT_1 PF00078.27 GBG78928.1 - 3.3e-25 88.9 0.0 5.8e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG78928.1 - 4.1e-16 58.8 0.4 1.1e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG78928.1 - 9.5e-13 48.4 0.0 2.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG78928.1 - 7.4e-06 26.1 0.0 3.1e-05 24.1 0.0 2.2 1 0 0 1 1 1 1 H2C2 zinc finger Dppa2_A PF14049.6 GBG78928.1 - 0.06 13.5 0.2 0.16 12.1 0.1 1.7 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates Integrase_H2C2 PF17921.1 GBG78929.1 - 1.5e-10 41.0 0.1 4e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG78929.1 - 4.1e-08 33.0 0.0 7.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG78929.1 - 1.9e-06 28.3 0.1 7.1e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG78929.1 - 6.7e-06 26.1 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78929.1 - 0.00022 21.5 0.0 0.00047 20.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG78929.1 - 0.00026 21.6 0.1 0.00087 19.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG78929.1 - 0.0057 16.4 1.2 0.011 15.5 1.2 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG78929.1 - 0.029 14.7 0.0 0.079 13.3 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease HBS1_N PF08938.10 GBG78929.1 - 1.1 9.7 8.1 11 6.4 5.6 3.0 2 0 0 2 2 2 0 HBS1 N-terminus RVT_1 PF00078.27 GBG78930.1 - 7.1e-09 35.5 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2025 PF09634.10 GBG78930.1 - 0.056 13.5 0.2 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2025) zinc_ribbon_4 PF13717.6 GBG78931.1 - 0.033 14.1 4.9 3.2 7.8 0.8 2.7 2 0 0 2 2 2 0 zinc-ribbon domain HECT_2 PF09814.9 GBG78931.1 - 0.085 11.7 1.5 5.9 5.6 0.2 2.1 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Eapp_C PF10238.9 GBG78931.1 - 0.19 11.8 0.6 3.8 7.6 0.9 2.2 2 1 0 2 2 2 0 E2F-associated phosphoprotein TPR_9 PF13371.6 GBG78932.1 - 7.8e-11 42.0 0.1 0.00014 21.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG78932.1 - 1.6e-10 40.4 0.6 0.062 13.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG78932.1 - 1.7e-10 40.2 0.2 0.042 14.0 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 GBG78932.1 - 2.8e-10 40.1 0.1 0.016 15.9 0.1 4.8 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG78932.1 - 1.6e-09 37.3 0.2 0.11 12.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 GBG78932.1 - 1.9e-08 34.7 1.1 0.0016 18.9 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG78932.1 - 1.3e-07 31.2 0.2 0.016 14.9 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_6 PF13174.6 GBG78932.1 - 7.5e-07 29.4 0.5 0.38 11.5 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG78932.1 - 2.6e-06 28.0 0.0 0.043 14.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG78932.1 - 0.00012 22.2 0.0 0.44 11.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 GBG78932.1 - 0.00066 19.4 0.1 0.018 14.8 0.1 2.3 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_MalT PF17874.1 GBG78932.1 - 0.0015 17.9 0.3 0.0085 15.5 0.5 1.9 1 1 1 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 GBG78932.1 - 0.0019 18.4 0.7 1.6 9.1 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 GBG78932.1 - 0.0056 17.0 0.2 2 8.8 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Elf4 PF07011.11 GBG78932.1 - 0.015 15.2 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Early Flowering 4 domain TPR_7 PF13176.6 GBG78932.1 - 0.018 15.1 0.1 2.7 8.2 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 GBG78932.1 - 0.021 14.6 0.4 0.33 10.6 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 GBG78932.1 - 0.04 14.2 0.0 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 GBG78932.1 - 0.048 12.4 0.0 0.16 10.7 0.0 1.7 1 1 1 2 2 2 0 Protein kinase G tetratricopeptide repeat NARP1 PF12569.8 GBG78932.1 - 0.049 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PPR PF01535.20 GBG78932.1 - 0.078 13.3 0.2 19 5.8 0.0 3.3 3 0 0 3 3 3 0 PPR repeat FokI_N PF02981.15 GBG78933.1 - 0.0053 16.9 0.7 0.0085 16.3 0.7 1.3 1 0 0 1 1 1 1 Restriction endonuclease FokI, recognition domain FtsK_SpoIIIE PF01580.18 GBG78933.1 - 2.1 7.6 6.3 8.1 5.7 6.4 1.8 1 1 0 1 1 1 0 FtsK/SpoIIIE family Med9 PF07544.13 GBG78933.1 - 6.6 6.9 17.8 1.5 8.9 0.5 3.4 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 WD40 PF00400.32 GBG78934.1 - 4.5e-06 27.3 0.0 0.014 16.2 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GBG78934.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 GBG78934.1 - 0.03 14.6 0.0 0.13 12.6 0.0 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF659 PF04937.15 GBG78935.1 - 1.3e-12 47.8 0.0 2.1e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) WD40 PF00400.32 GBG78936.1 - 3.1e-15 56.3 9.2 2.6e-05 24.9 0.4 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Retrotrans_gag PF03732.17 GBG78936.1 - 0.0026 18.0 0.2 0.038 14.3 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein Cytochrom_D1 PF02239.16 GBG78936.1 - 0.0058 15.2 0.5 1.6 7.2 0.1 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Borrelia_P83 PF05262.11 GBG78936.1 - 0.1 11.1 8.6 0.15 10.6 8.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CSRNP_N PF16019.5 GBG78936.1 - 0.13 12.2 3.2 0.3 11.0 3.2 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FAM60A PF15396.6 GBG78936.1 - 1.3 9.0 6.4 2.3 8.2 6.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A APS_kinase PF01583.20 GBG78938.1 - 2.7e-67 225.6 0.0 3.7e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 GBG78938.1 - 5.9e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ParA PF10609.9 GBG78938.1 - 0.0008 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_29 PF13555.6 GBG78938.1 - 0.00089 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 GBG78938.1 - 0.001 19.6 0.0 0.0016 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG78938.1 - 0.0015 18.9 0.1 0.0032 17.9 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain CbiA PF01656.23 GBG78938.1 - 0.0021 18.1 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 GBG78938.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MeaB PF03308.16 GBG78938.1 - 0.043 12.8 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 GBG78938.1 - 0.047 14.2 0.0 0.076 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 GBG78938.1 - 0.076 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 GBG78938.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GBG78938.1 - 0.092 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GBG78938.1 - 0.096 13.2 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GBG78938.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GBG78938.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SMC_N PF02463.19 GBG78938.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 GBG78938.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 GBG78938.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.12 GBG78938.1 - 0.21 11.4 0.2 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RVT_1 PF00078.27 GBG78939.1 - 5.1e-30 104.6 0.0 8.1e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78939.1 - 1.2e-25 89.4 0.0 3.9e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78939.1 - 7.6e-22 77.6 0.0 2.8e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG78939.1 - 1.1e-06 29.2 0.0 3.7e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78939.1 - 1.5e-06 28.6 0.0 5.3e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG78939.1 - 8e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease BORCS8 PF10167.9 GBG78939.1 - 8.2e-05 22.5 0.0 0.00024 21.0 0.0 1.8 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 Asp_protease PF09668.10 GBG78939.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG78939.1 - 0.015 15.5 0.4 0.1 12.9 0.1 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG78940.1 - 5.1e-30 104.6 0.0 8.1e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78940.1 - 1.2e-25 89.4 0.0 3.9e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78940.1 - 7.7e-22 77.6 0.0 2.9e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG78940.1 - 1.1e-06 29.2 0.0 3.7e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78940.1 - 1.5e-06 28.6 0.0 5.3e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG78940.1 - 8e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease BORCS8 PF10167.9 GBG78940.1 - 8.9e-05 22.4 0.0 0.00025 20.9 0.0 1.8 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 Asp_protease PF09668.10 GBG78940.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG78940.1 - 0.016 15.5 0.4 0.1 12.9 0.1 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein PHD PF00628.29 GBG78942.1 - 3.1e-08 33.4 6.1 6.7e-08 32.3 6.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 GBG78942.1 - 0.00069 19.7 4.7 0.0026 17.8 4.7 2.1 1 0 0 1 1 1 1 PHD-finger Neisseria_TspB PF05616.13 GBG78942.1 - 2 6.8 6.2 3.5 6.0 6.2 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Myc_N PF01056.18 GBG78942.1 - 8.3 6.2 13.4 6.2 6.6 1.1 3.4 3 0 0 3 3 3 0 Myc amino-terminal region RVT_1 PF00078.27 GBG78943.1 - 7.9e-23 81.1 0.0 4.6e-20 72.1 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG78943.1 - 0.00067 19.9 1.9 0.0053 17.0 0.0 3.3 4 0 0 4 4 4 1 Retrotransposon gag protein OTCace PF00185.24 GBG78944.1 - 8.8e-53 178.6 0.1 1.4e-52 178.0 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 GBG78944.1 - 2.5e-46 157.3 0.0 4.2e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain cEGF PF12662.7 GBG78944.1 - 0.095 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like Glyco_hydro_101 PF12905.7 GBG78944.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase Transferrin PF00405.17 GBG78945.1 - 2.9e-32 112.2 0.0 4.5e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Transferrin Phosphonate-bd PF12974.7 GBG78945.1 - 7e-06 25.8 0.0 4.5e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein KH_7 PF17214.3 GBG78946.1 - 0.061 13.3 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 KH domain BTHB PF18410.1 GBG78946.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Basic tilted helix bundle domain Rib_5-P_isom_A PF06026.14 GBG78947.1 - 2.8e-64 215.9 0.0 3.3e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) BSP_II PF05432.11 GBG78948.1 - 0.00038 20.3 21.8 0.00057 19.7 21.8 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 GBG78948.1 - 0.00093 19.2 14.3 0.012 15.6 0.7 2.1 2 0 0 2 2 2 2 Myc amino-terminal region FAM176 PF14851.6 GBG78948.1 - 0.0019 17.9 13.7 0.08 12.6 1.8 2.2 2 0 0 2 2 2 2 FAM176 family PBP1_TM PF14812.6 GBG78948.1 - 0.0069 16.7 9.9 0.065 13.6 3.8 2.2 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Prothymosin PF03247.14 GBG78948.1 - 0.022 15.2 30.4 0.15 12.5 10.1 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.10 GBG78948.1 - 0.037 14.4 2.1 0.037 14.4 2.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 GBG78948.1 - 0.12 12.1 14.4 0.64 9.8 1.5 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein GEN1_C PF18380.1 GBG78948.1 - 0.14 13.1 10.8 1.4 9.9 2.9 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain WRNPLPNID PF15017.6 GBG78948.1 - 0.16 12.9 20.6 1 10.3 8.6 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box BAF1_ABF1 PF04684.13 GBG78948.1 - 0.21 10.6 9.1 0.24 10.4 9.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RXT2_N PF08595.11 GBG78948.1 - 0.31 11.1 11.2 1.1 9.2 2.0 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal MRNIP PF15749.5 GBG78948.1 - 0.38 11.5 11.5 3 8.6 2.8 2.2 2 0 0 2 2 2 0 MRN-interacting protein Nha1_C PF08619.10 GBG78948.1 - 0.43 9.7 19.0 0.55 9.4 19.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4746 PF15928.5 GBG78948.1 - 0.84 9.0 18.6 0.4 10.0 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF5523 PF17661.1 GBG78948.1 - 1.1 8.9 17.0 2.7 7.6 4.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Sporozoite_P67 PF05642.11 GBG78948.1 - 1.3 7.1 6.1 2.2 6.3 0.2 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF2956 PF11169.8 GBG78948.1 - 1.8 8.8 6.8 6.2 7.1 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) GOLD_2 PF13897.6 GBG78948.1 - 2.1 8.8 9.6 3.7 8.0 1.3 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking TFIIE-A_C PF11521.8 GBG78948.1 - 2.4 8.5 19.4 0.46 10.8 1.7 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha E7 PF00527.18 GBG78948.1 - 3.3 8.0 12.5 3.7 7.8 2.4 2.5 2 0 0 2 2 2 0 E7 protein, Early protein NOA36 PF06524.12 GBG78948.1 - 4.3 6.6 19.5 4.4 6.5 6.1 2.1 2 0 0 2 2 2 0 NOA36 protein RPN2_C PF18004.1 GBG78948.1 - 4.5 7.2 16.3 6.5 6.7 3.6 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Tub_N PF16322.5 GBG78948.1 - 6 7.2 19.4 9.5 6.6 2.2 2.1 2 0 0 2 2 2 0 Tubby N-terminal eIF3_subunit PF08597.10 GBG78948.1 - 8.2 6.3 24.7 6.8 6.5 11.7 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit TFB6 PF17110.5 GBG78948.1 - 9.4 5.9 10.3 12 5.6 0.8 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF1336 PF07059.12 GBG78949.1 - 2.1e-58 198.1 0.0 3e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) NHL PF01436.21 GBG78950.1 - 0.00067 19.6 0.0 0.12 12.4 0.1 2.9 2 0 0 2 2 2 1 NHL repeat Retrotrans_gag PF03732.17 GBG78950.1 - 0.0045 17.2 2.3 0.0079 16.5 0.3 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein SGL PF08450.12 GBG78950.1 - 0.047 13.3 0.2 0.7 9.4 0.2 2.6 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region NAM-associated PF14303.6 GBG78950.1 - 0.15 12.8 8.0 0.25 12.1 8.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TFIIA PF03153.13 GBG78950.1 - 2.4 8.1 11.8 4.7 7.1 11.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RVT_1 PF00078.27 GBG78951.1 - 1.4e-31 109.7 0.1 2.1e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78951.1 - 1.6e-24 85.9 0.0 3.1e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78951.1 - 1.1e-22 80.2 0.0 1.9e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG78952.1 - 2.7e-30 105.2 0.0 5.5e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG78952.1 - 2.1e-06 27.4 0.4 2.1e-06 27.4 0.4 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region ZapB PF06005.12 GBG78953.1 - 0.0016 18.8 18.8 2 8.9 0.0 5.3 4 1 0 4 4 3 1 Cell division protein ZapB DivIC PF04977.15 GBG78953.1 - 0.0021 17.8 0.3 0.0021 17.8 0.3 4.7 3 1 1 4 4 4 1 Septum formation initiator KIAA1430 PF13879.6 GBG78953.1 - 0.0084 16.9 3.9 0.021 15.6 3.9 1.8 1 0 0 1 1 1 1 KIAA1430 homologue CCDC92 PF14916.6 GBG78953.1 - 0.0093 15.7 10.5 7.7 6.4 0.1 4.9 3 2 2 5 5 5 2 Coiled-coil domain of unknown function SlyX PF04102.12 GBG78953.1 - 0.042 14.5 5.6 20 5.9 0.0 3.9 3 1 1 4 4 4 0 SlyX DUF4515 PF14988.6 GBG78953.1 - 0.1 12.4 12.9 0.42 10.4 1.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) Lzipper-MIP1 PF14389.6 GBG78953.1 - 0.12 12.6 8.9 19 5.7 0.1 4.9 4 1 0 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 T6PP_N PF18572.1 GBG78953.1 - 0.16 11.8 3.6 3.3 7.6 3.6 2.5 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain NYD-SP28_assoc PF14775.6 GBG78953.1 - 0.51 10.5 16.5 16 5.7 0.5 5.0 5 0 0 5 5 5 0 Sperm tail C-terminal domain PikAIV_N PF18605.1 GBG78953.1 - 0.58 9.8 17.2 4.4 7.0 0.6 4.5 4 0 0 4 4 4 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain FlaC_arch PF05377.11 GBG78953.1 - 1.3 9.5 11.2 2.2 8.7 0.2 4.2 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 GBG78953.1 - 3.6 7.7 21.7 15 5.8 0.4 4.8 5 0 0 5 5 5 0 Basic region leucine zipper bZIP_1 PF00170.21 GBG78953.1 - 4.6 7.4 20.3 2.8 8.1 0.3 5.2 4 1 1 5 5 5 0 bZIP transcription factor CASP_C PF08172.12 GBG78953.1 - 6 6.1 8.4 3.3 7.0 0.0 2.8 2 1 0 2 2 2 0 CASP C terminal M PF02370.16 GBG78953.1 - 6.7 7.6 7.3 25 5.9 0.0 4.1 4 0 0 4 4 3 0 M protein repeat Herpes_BLRF2 PF05812.12 GBG78953.1 - 7.2 6.8 12.2 1.6 8.9 1.8 3.7 2 1 2 4 4 4 0 Herpesvirus BLRF2 protein Integrase_H2C2 PF17921.1 GBG78954.1 - 1.1e-13 51.0 0.1 2.2e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78954.1 - 0.0012 19.0 0.0 0.004 17.3 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger UCH PF00443.29 GBG78955.1 - 2.4e-31 109.2 0.0 5.3e-21 75.3 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG78955.1 - 1.2e-08 34.9 0.0 0.00068 19.3 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_4 PF13717.6 GBG78955.1 - 1 9.3 5.6 7.6 6.6 0.4 3.6 3 0 0 3 3 3 0 zinc-ribbon domain UCH PF00443.29 GBG78956.1 - 9.9e-32 110.4 0.0 2.3e-21 76.5 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG78956.1 - 1.6e-08 34.5 0.0 0.00086 19.0 0.1 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_4 PF13717.6 GBG78956.1 - 1 9.4 5.6 7.5 6.6 0.4 3.6 3 0 0 3 3 3 0 zinc-ribbon domain YbjQ_1 PF01906.17 GBG78959.1 - 1.6e-07 31.9 0.3 0.00061 20.4 0.1 2.4 2 0 0 2 2 2 2 Putative heavy-metal-binding HSP70 PF00012.20 GBG78961.1 - 1.5e-147 492.4 0.0 2e-147 492.0 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG78961.1 - 9.4e-17 60.8 1.2 2.1e-07 30.1 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 GBG78961.1 - 0.0004 20.8 0.5 0.031 14.7 0.0 3.0 2 1 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.16 GBG78961.1 - 0.00086 19.1 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 GBG78961.1 - 0.017 14.1 0.4 0.23 10.4 0.3 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain RuvX PF03652.15 GBG78961.1 - 0.064 13.7 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Holliday junction resolvase IATP PF04568.12 GBG78961.1 - 3.2 8.2 5.5 2.8 8.4 0.4 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP HSP70 PF00012.20 GBG78963.1 - 5.4e-148 493.8 0.0 6.9e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG78963.1 - 4.9e-18 65.0 1.3 5.7e-08 31.9 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 GBG78963.1 - 2.4e-05 24.7 0.2 0.02 15.3 0.0 2.9 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.16 GBG78963.1 - 0.0002 21.1 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 GBG78963.1 - 0.0045 16.0 0.6 0.077 12.0 0.5 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain RuvX PF03652.15 GBG78963.1 - 0.04 14.3 0.2 0.12 12.7 0.1 1.8 2 0 0 2 2 2 0 Holliday junction resolvase PilM_2 PF11104.8 GBG78963.1 - 0.059 12.4 0.0 0.47 9.4 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; StbA PF06406.11 GBG78963.1 - 0.19 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein IATP PF04568.12 GBG78963.1 - 0.24 11.9 5.6 0.6 10.6 0.2 2.6 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP HSP70 PF00012.20 GBG78964.1 - 3.7e-150 501.0 0.0 4.6e-150 500.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG78964.1 - 1.5e-18 66.8 1.6 1.3e-08 34.0 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 GBG78964.1 - 3.4e-05 24.2 0.3 0.023 15.1 0.0 2.8 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.16 GBG78964.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 GBG78964.1 - 0.029 13.4 1.1 0.38 9.7 0.8 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain RuvX PF03652.15 GBG78964.1 - 0.045 14.1 0.1 0.13 12.7 0.1 1.8 1 0 0 1 1 1 0 Holliday junction resolvase StbA PF06406.11 GBG78964.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 StbA protein RT_RNaseH_2 PF17919.1 GBG78966.1 - 7.8e-32 109.3 0.0 2.8e-31 107.5 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78966.1 - 8.2e-31 106.4 0.0 2.4e-30 104.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78966.1 - 1.1e-18 67.1 0.7 2.3e-18 66.0 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78966.1 - 0.00017 21.7 0.2 0.00047 20.3 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG78966.1 - 0.0012 19.1 0.0 0.0032 17.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG78966.1 - 0.0025 17.4 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG78966.1 - 0.39 10.3 0.0 0.39 10.3 0.0 3.1 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Peptidase_M10 PF00413.24 GBG78967.1 - 7.2e-48 162.4 0.2 9.8e-48 162.0 0.2 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 GBG78967.1 - 3.5e-11 43.1 0.1 2.3e-10 40.5 0.0 2.4 3 0 0 3 3 3 1 Putative peptidoglycan binding domain Astacin PF01400.24 GBG78967.1 - 0.00027 20.6 0.1 0.24 11.0 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.11 GBG78967.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_3 PF13582.6 GBG78967.1 - 0.033 14.7 0.1 0.063 13.8 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 GBG78967.1 - 0.049 12.9 0.0 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Met-zincin Metallopep PF12044.8 GBG78967.1 - 0.062 11.9 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.9 GBG78967.1 - 0.069 12.1 0.1 0.16 10.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase M66 RVT_1 PF00078.27 GBG78968.1 - 4e-25 88.6 0.1 6.4e-25 88.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG78968.1 - 1.6e-12 47.7 0.0 4.3e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG78968.1 - 3.3e-12 46.3 1.8 9.7e-12 44.8 0.0 2.7 4 0 0 4 4 4 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG78968.1 - 0.0003 20.9 0.0 0.00083 19.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG78968.1 - 0.007 17.0 0.0 0.024 15.3 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease BUD22 PF09073.10 GBG78969.1 - 1.1 8.6 38.0 1.5 8.1 38.0 1.3 1 0 0 1 1 1 0 BUD22 Endostatin PF06482.11 GBG78969.1 - 3.3 7.1 6.1 1.5 8.2 4.0 1.5 1 1 0 1 1 1 0 Collagenase NC10 and Endostatin zf-CCHC PF00098.23 GBG78970.1 - 0.29 11.3 1.9 0.71 10.1 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle HSP70 PF00012.20 GBG78971.1 - 1.3e-140 469.5 0.0 2e-79 267.4 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG78971.1 - 7.4e-13 48.0 0.3 4.3e-05 22.5 0.0 3.2 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 GBG78971.1 - 0.0067 16.8 0.1 2.6 8.5 0.0 3.3 3 1 0 3 3 3 1 Cell division protein FtsA BRX PF08381.11 GBG78971.1 - 0.064 12.6 0.6 0.13 11.6 0.6 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Raco_middle PF17651.1 GBG78971.1 - 0.11 12.2 0.2 7.3 6.3 0.0 2.8 3 0 0 3 3 3 0 RACo middle region HSP70 PF00012.20 GBG78974.1 - 8.4e-144 480.0 0.0 3.1e-143 478.1 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG78974.1 - 3.7e-14 52.3 1.5 5.8e-10 38.5 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 GBG78974.1 - 5.4e-05 23.5 0.4 0.059 13.8 0.0 2.8 2 0 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.16 GBG78974.1 - 0.00033 20.4 0.0 0.00057 19.7 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 GBG78975.1 - 5.5e-149 497.1 0.0 3.1e-147 491.3 0.0 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG78975.1 - 4.4e-14 52.0 5.3 1.6e-08 33.7 0.1 3.2 2 1 0 3 3 3 3 MreB/Mbl protein FGGY_C PF02782.16 GBG78975.1 - 6e-06 26.1 0.1 1.4e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG78975.1 - 4.1e-05 24.0 0.6 0.011 16.1 0.0 3.0 2 1 0 2 2 2 1 Cell division protein FtsA DDR PF08841.10 GBG78975.1 - 0.0034 16.4 0.6 0.0063 15.6 0.6 1.3 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain DMRL_synthase PF00885.19 GBG78975.1 - 0.049 13.4 0.3 0.16 11.8 0.3 1.8 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase PilM_2 PF11104.8 GBG78975.1 - 0.12 11.3 0.0 0.33 9.9 0.0 1.6 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; PPP4R2 PF09184.11 GBG78976.1 - 0.1 12.2 11.6 0.15 11.7 11.6 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIF_alpha PF05793.12 GBG78976.1 - 0.48 8.9 16.5 0.73 8.4 16.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop53 PF07767.11 GBG78976.1 - 0.95 8.8 18.3 1.3 8.3 18.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.12 GBG78976.1 - 1.1 8.6 20.2 1.4 8.3 20.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG78976.1 - 1.3 7.3 15.8 1.7 6.9 15.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG78976.1 - 2.6 6.1 20.7 3.4 5.8 20.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG78976.1 - 4.1 6.7 14.8 5.7 6.3 14.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Retrotrans_gag PF03732.17 GBG78978.1 - 0.006 16.8 0.6 0.07 13.4 0.1 2.7 2 1 1 3 3 3 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG78978.1 - 0.0065 17.1 0.1 0.016 15.8 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG78978.1 - 0.038 14.5 0.1 0.1 13.2 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG78978.1 - 0.11 12.8 0.1 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease HSP70 PF00012.20 GBG78979.1 - 1.8e-100 336.9 0.0 8.4e-43 146.4 0.0 4.1 3 1 0 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 GBG78979.1 - 0.082 11.7 7.0 4.1 6.1 0.0 3.4 4 0 0 4 4 4 0 MreB/Mbl protein RVT_1 PF00078.27 GBG78980.1 - 8.9e-16 58.1 0.0 2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG78980.1 - 2.2e-08 34.6 0.0 6.4e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG78980.1 - 2.9e-08 34.3 0.0 7.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG78980.1 - 3.4e-06 26.9 0.0 8.1e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG78980.1 - 5.3e-06 26.2 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF4187 PF13821.6 GBG78980.1 - 0.00091 19.0 0.4 0.0026 17.5 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG78980.1 - 0.0018 18.5 1.2 0.0075 16.5 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF1639 PF07797.14 GBG78981.1 - 4.8e-07 29.6 0.0 4.8e-07 29.6 0.0 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1639) Presenilin PF01080.17 GBG78981.1 - 0.0072 15.1 17.9 0.0082 14.9 17.9 1.2 1 0 0 1 1 1 1 Presenilin SOBP PF15279.6 GBG78981.1 - 0.02 15.5 31.8 0.025 15.2 31.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF966 PF06136.13 GBG78981.1 - 0.13 12.0 15.1 0.16 11.6 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.9 GBG78981.1 - 0.13 10.8 12.7 0.15 10.6 12.7 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 GBG78981.1 - 0.15 11.6 21.4 0.18 11.3 21.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Med15 PF09606.10 GBG78981.1 - 0.28 9.8 51.1 0.32 9.6 51.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM60A PF15396.6 GBG78981.1 - 0.45 10.5 19.7 0.9 9.5 18.9 1.7 2 0 0 2 2 2 0 Protein Family FAM60A Zip PF02535.22 GBG78981.1 - 0.5 9.5 11.4 0.58 9.3 11.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 GBG78981.1 - 0.68 8.2 14.9 0.78 8.0 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 GBG78981.1 - 0.8 8.4 18.5 0.97 8.1 18.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF-3_zeta PF05091.12 GBG78981.1 - 0.91 8.4 21.3 1.3 7.9 21.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 GBG78981.1 - 1.1 9.0 20.4 1.7 8.4 20.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 GBG78981.1 - 1.5 6.8 18.3 1.6 6.7 18.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sin_N PF04801.13 GBG78981.1 - 1.7 7.8 28.8 2.1 7.5 28.8 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region SLC12 PF03522.15 GBG78981.1 - 2.1 7.3 21.5 2.9 6.8 21.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 GBG78981.1 - 2.7 5.0 23.5 3.1 4.8 23.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Menin PF05053.13 GBG78981.1 - 3.9 5.7 13.9 18 3.5 14.0 1.8 2 0 0 2 2 2 0 Menin PAT1 PF09770.9 GBG78981.1 - 3.9 5.6 41.4 4.7 5.4 41.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK5_activator PF03261.15 GBG78981.1 - 6.1 6.3 18.8 7.4 6.0 18.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4551 PF15087.6 GBG78981.1 - 7.7 5.2 23.4 10 4.8 23.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MDM10 PF12519.8 GBG78981.1 - 8.3 5.1 16.6 11 4.7 16.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ndc1_Nup PF09531.10 GBG78981.1 - 9.9 4.7 22.1 12 4.4 22.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RVT_1 PF00078.27 GBG78982.1 - 3e-26 92.3 0.0 5.4e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG78982.1 - 1.2e-20 73.8 0.0 3.4e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG78982.1 - 1.8e-16 60.0 0.0 7.7e-16 58.0 0.0 2.2 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78982.1 - 5.6e-10 39.2 0.0 1.5e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG78982.1 - 0.00052 20.2 0.1 0.0032 17.7 0.1 2.4 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.26 GBG78982.1 - 0.00065 19.9 0.1 0.0019 18.3 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG78982.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain 2-oxoacid_dh PF00198.23 GBG78983.1 - 1.4e-71 240.7 0.0 1.9e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GBG78983.1 - 1.2e-16 60.3 0.3 1.2e-16 60.3 0.3 2.4 3 0 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.17 GBG78983.1 - 3.3e-11 43.3 0.0 8.3e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GBG78983.1 - 0.0031 17.3 0.0 0.13 12.1 0.0 2.8 2 1 1 3 3 3 1 Biotin-lipoyl like 2-oxoacid_dh PF00198.23 GBG78984.1 - 4.9e-71 238.9 0.0 6.7e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GBG78984.1 - 4.6e-17 61.6 1.2 1.2e-16 60.3 0.3 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 GBG78984.1 - 3e-11 43.5 0.0 8.3e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GBG78984.1 - 0.0031 17.3 0.0 0.13 12.1 0.0 2.8 2 1 1 3 3 3 1 Biotin-lipoyl like RVT_1 PF00078.27 GBG78986.1 - 1.4e-33 116.3 0.0 2.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG78986.1 - 6.4e-33 112.8 0.0 8.7e-17 61.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78986.1 - 5.9e-24 84.4 0.0 1.2e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4399 PF14347.6 GBG78986.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) zf-RVT PF13966.6 GBG78987.1 - 2.9e-09 37.5 1.8 5.4e-09 36.6 0.4 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Integrase_H2C2 PF17921.1 GBG78988.1 - 1.6e-14 53.7 2.0 2.6e-14 53.1 0.1 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG78988.1 - 1.2e-12 48.1 0.0 3.3e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG78988.1 - 8.7e-12 44.8 0.0 1.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG78988.1 - 2.3e-07 30.6 0.0 2.4e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG78988.1 - 0.0012 19.0 0.1 0.0035 17.5 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Dppa2_A PF14049.6 GBG78988.1 - 0.078 13.1 0.0 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates DUF1191 PF06697.12 GBG78990.1 - 3.4e-05 23.7 0.0 0.00016 21.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1191) DUF4720 PF15846.5 GBG78990.1 - 0.082 12.8 0.1 13 5.7 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4720) RVP_2 PF08284.11 GBG78991.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG78991.1 - 0.43 10.3 2.6 0.42 10.3 0.2 2.3 3 0 0 3 3 3 0 Topoisomerase I zinc-ribbon-like RT_RNaseH_2 PF17919.1 GBG78992.1 - 6.9e-28 96.6 0.0 1.3e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG78992.1 - 2.2e-26 92.2 0.0 5.9e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG78992.1 - 2.2e-15 56.8 0.0 3.5e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG78992.1 - 5.3e-15 55.6 0.0 8.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2249 PF10006.9 GBG78992.1 - 0.023 14.6 0.0 2.8 7.9 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Glyco_trans_2_3 PF13632.6 GBG78992.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DDE_Tnp_1_7 PF13843.6 GBG78996.1 - 2.4e-21 76.5 0.8 2.9e-21 76.2 0.1 1.5 2 0 0 2 2 2 1 Transposase IS4 RVT_1 PF00078.27 GBG78996.1 - 6e-14 52.1 0.0 1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG78998.1 - 1.5e-05 24.8 2.3 2.5e-05 24.1 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG78998.1 - 0.00093 19.0 0.3 0.0015 18.3 0.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG78998.1 - 0.016 15.2 2.2 0.06 13.3 0.9 2.6 2 0 0 2 2 2 0 Zinc knuckle Myco_haema PF05692.12 GBG78998.1 - 0.062 12.3 3.1 0.088 11.8 3.1 1.1 1 0 0 1 1 1 0 Mycoplasma haemagglutinin MMgT PF10270.9 GBG78998.1 - 0.56 10.6 2.4 0.4 11.1 0.2 1.9 1 1 1 2 2 2 0 Membrane magnesium transporter Plasmodium_Vir PF05795.11 GBG78998.1 - 0.72 9.2 8.5 0.91 8.9 8.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ALMT PF11744.8 GBG78998.1 - 1.5 7.6 12.8 1.9 7.2 12.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2072 PF09845.9 GBG78998.1 - 2.9 8.2 16.0 5 7.4 0.2 2.4 2 0 0 2 2 2 0 Zn-ribbon containing protein DUF3597 PF12200.8 GBG78999.1 - 0.02 15.4 1.1 0.033 14.7 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3597) Poxvirus_B22R PF04395.12 GBG78999.1 - 0.021 14.4 6.9 0.028 13.9 6.9 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein RR_TM4-6 PF06459.12 GBG78999.1 - 0.31 10.8 14.4 0.38 10.5 14.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2151 PF10221.9 GBG78999.1 - 1 7.9 7.5 1.2 7.7 7.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator NPR3 PF03666.13 GBG78999.1 - 1.2 7.8 7.0 1.4 7.6 7.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 GBG78999.1 - 1.6 7.0 10.7 1.7 6.8 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.6 GBG78999.1 - 1.7 8.5 13.4 2.7 7.9 13.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Radial_spoke_3 PF06098.11 GBG78999.1 - 2 7.6 16.9 2.7 7.2 16.9 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 RNA_pol_Rpc4 PF05132.14 GBG78999.1 - 2.1 8.7 7.4 11 6.5 7.2 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Hid1 PF12722.7 GBG78999.1 - 2.2 6.3 4.2 2.3 6.2 4.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2058 PF09831.9 GBG78999.1 - 3.5 7.7 15.9 5.2 7.2 15.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) ALMT PF11744.8 GBG78999.1 - 4.8 5.9 5.7 5.6 5.7 5.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 GBG78999.1 - 5.6 5.6 9.2 6.6 5.4 9.2 1.1 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.12 GBG78999.1 - 7.2 5.9 15.7 11 5.3 15.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger MCM_bind PF09739.9 GBG78999.1 - 7.9 4.8 10.5 9.6 4.5 10.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Connexin PF00029.19 GBG78999.1 - 9.1 6.0 8.0 12 5.6 8.0 1.2 1 0 0 1 1 1 0 Connexin Sec62 PF03839.16 GBG78999.1 - 9.2 5.7 13.2 12 5.3 13.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 BT1 PF03092.16 GBG78999.1 - 9.9 4.2 5.0 12 4.0 5.0 1.0 1 0 0 1 1 1 0 BT1 family Dimer_Tnp_hAT PF05699.14 GBG79000.1 - 0.0034 17.1 0.8 0.0078 16.0 0.2 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region GLTSCR1 PF15249.6 GBG79001.1 - 1.4 9.3 7.7 20 5.7 0.2 3.8 4 0 0 4 4 4 0 Conserved region of unknown function on GLTSCR protein RT_RNaseH_2 PF17919.1 GBG79003.1 - 6.7e-28 96.7 0.0 1.8e-27 95.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79003.1 - 5.3e-27 94.2 0.1 2e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79003.1 - 1.4e-08 34.5 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG79004.1 - 8.1e-13 48.5 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG79006.1 - 2.4e-23 82.0 0.0 4.8e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79006.1 - 4.1e-22 78.4 0.0 9.4e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79006.1 - 5.9e-22 78.3 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79006.1 - 2.1e-19 69.4 0.1 4.5e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79006.1 - 2e-07 31.2 0.1 2.2e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Integrin_b_cyt PF08725.11 GBG79006.1 - 0.0093 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain zf-H2C2 PF09337.10 GBG79006.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG79007.1 - 7.4e-17 61.6 0.0 1.6e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79007.1 - 1.7e-15 57.2 0.0 6.4e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG79007.1 - 2.4e-07 30.7 0.0 1.4e-06 28.3 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG79007.1 - 0.003 17.8 8.4 0.015 15.5 0.4 3.9 2 2 1 3 3 3 1 Retrotransposon gag protein FtsK_4TM PF13491.6 GBG79007.1 - 0.092 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE SlyX PF04102.12 GBG79007.1 - 0.11 13.1 0.1 0.11 13.1 0.1 5.1 6 0 0 6 6 6 0 SlyX APG6_N PF17675.1 GBG79007.1 - 0.37 11.3 0.0 0.37 11.3 0.0 3.5 3 0 0 3 3 3 0 Apg6 coiled-coil region RVT_1 PF00078.27 GBG79008.1 - 3.3e-26 92.2 0.1 5.2e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79008.1 - 3.2e-12 46.3 0.0 7e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79008.1 - 5.2e-09 36.3 0.1 1.8e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG79008.1 - 4.8e-08 33.0 0.2 1.2e-07 31.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG79008.1 - 1.1e-06 28.8 0.1 0.0075 16.5 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG79008.1 - 0.042 13.8 0.1 0.082 12.8 0.1 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Ribonuc_2-5A PF06479.12 GBG79009.1 - 2e-16 60.3 0.9 5.2e-16 59.0 0.9 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A RT_RNaseH_2 PF17919.1 GBG79009.1 - 4.6e-13 49.1 0.0 9.8e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79009.1 - 0.0001 22.5 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 GBG79009.1 - 0.00057 19.3 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RVT_1 PF00078.27 GBG79010.1 - 2e-21 76.6 0.0 7.1e-21 74.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79010.1 - 5.4e-18 64.9 0.0 1.5e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79010.1 - 1.3e-08 35.1 0.0 3.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG79010.1 - 0.0039 17.4 0.1 0.0039 17.4 0.1 4.7 6 2 1 7 7 7 1 Retrotransposon gag protein Sulfatase_C PF14707.6 GBG79010.1 - 0.095 13.4 2.4 0.2 12.4 0.4 2.5 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DUF2781 PF10914.8 GBG79010.1 - 0.11 12.8 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) HXXSHH PF07586.11 GBG79010.1 - 3.2 7.3 8.2 8.5 5.8 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1552) PIF1 PF05970.14 GBG79011.1 - 3.9e-100 335.6 0.0 6.3e-100 334.9 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase RT_RNaseH_2 PF17919.1 GBG79011.1 - 2.6e-59 197.5 0.0 3.8e-28 97.5 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79011.1 - 7.6e-57 190.1 1.4 2.2e-27 95.4 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Helitron_like_N PF14214.6 GBG79011.1 - 1.4e-56 191.7 0.0 1.4e-56 191.7 0.0 1.9 2 0 0 2 2 1 1 Helitron helicase-like domain at N-terminus Integrase_H2C2 PF17921.1 GBG79011.1 - 7.1e-18 64.5 0.8 2.1e-17 63.0 0.8 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Pkinase PF00069.25 GBG79011.1 - 2.5e-12 46.7 0.2 1.8e-10 40.6 0.1 2.5 2 0 0 2 2 2 1 Protein kinase domain AAA_30 PF13604.6 GBG79011.1 - 1.6e-09 37.7 0.0 4.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Pkinase_Tyr PF07714.17 GBG79011.1 - 2.1e-07 30.5 0.0 4.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase rve PF00665.26 GBG79011.1 - 4.6e-05 23.6 0.1 0.0002 21.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG79011.1 - 0.0072 16.5 0.1 0.027 14.7 0.1 2.1 1 0 0 1 1 1 1 H2C2 zinc finger AAA_19 PF13245.6 GBG79011.1 - 0.016 15.6 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 GBG79011.1 - 0.023 14.2 0.8 0.62 9.5 0.2 2.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79013.1 - 3.4e-20 71.9 0.1 6.5e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79013.1 - 1.5e-16 60.6 0.0 3.9e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79013.1 - 0.00027 21.1 0.0 0.00079 19.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG79013.1 - 0.00059 19.8 0.1 0.0016 18.4 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG79013.1 - 0.87 9.4 2.4 1.7 8.5 0.0 3.0 3 0 0 3 3 3 0 Integrase core domain SR-25 PF10500.9 GBG79013.1 - 1.2 8.7 9.0 1.8 8.1 3.7 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 GBG79014.1 - 5.6e-26 91.4 0.0 9.1e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YabA PF06156.13 GBG79014.1 - 0.033 14.8 0.8 0.16 12.6 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA APG17 PF04108.12 GBG79014.1 - 0.043 12.9 0.8 1.7 7.7 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 FliD_N PF02465.18 GBG79014.1 - 0.11 13.2 2.6 0.46 11.2 1.1 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ATG16 PF08614.11 GBG79014.1 - 0.12 12.6 2.3 0.36 11.0 2.3 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 GBG79014.1 - 0.13 12.6 0.2 0.32 11.4 0.2 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CENP-N PF05238.13 GBG79015.1 - 0.0095 15.3 1.7 0.028 13.8 0.0 2.6 2 1 0 2 2 2 1 Kinetochore protein CHL4 like zf-CCHC PF00098.23 GBG79017.1 - 2.6e-06 27.3 1.6 7.3e-06 25.8 1.6 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF4980 PF16352.5 GBG79017.1 - 0.071 13.1 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4980) Preseq_ALAS PF09029.10 GBG79017.1 - 0.15 12.5 3.3 0.15 12.6 1.5 1.9 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence zf-CCHC_4 PF14392.6 GBG79017.1 - 0.31 10.8 1.9 1 9.2 1.9 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG79017.1 - 0.5 10.3 2.9 1 9.2 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Mem_trans PF03547.18 GBG79017.1 - 0.52 8.6 0.9 0.66 8.3 0.9 1.1 1 0 0 1 1 1 0 Membrane transport protein Dimer_Tnp_hAT PF05699.14 GBG79018.1 - 0.0038 17.0 0.1 0.0064 16.3 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCHC PF00098.23 GBG79020.1 - 0.00027 20.9 2.1 0.00056 19.9 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG79020.1 - 1.2 9.0 2.9 2.2 8.2 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 GBG79021.1 - 2.2e-08 34.6 0.0 4.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79021.1 - 3.7e-08 33.2 0.0 7.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG79021.1 - 2.8e-06 27.8 0.0 6.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG79021.1 - 0.0017 18.5 0.9 0.013 15.8 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG79021.1 - 0.0053 16.5 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Tudor-knot PF11717.8 GBG79021.1 - 0.042 13.8 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF4187 PF13821.6 GBG79021.1 - 0.042 13.6 1.7 0.13 12.0 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG79021.1 - 0.089 12.1 6.3 0.2 11.0 6.3 1.5 1 0 0 1 1 1 0 FAM76 protein Podoplanin PF05808.11 GBG79022.1 - 2 8.5 6.5 6.2 6.9 0.3 2.7 1 1 2 3 3 3 0 Podoplanin RVT_1 PF00078.27 GBG79026.1 - 1.8e-28 99.6 0.0 3.5e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG79026.1 - 3.6e-07 30.7 0.0 1.1e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79026.1 - 5.2e-05 23.7 0.0 0.00014 22.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG79026.1 - 0.00064 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG79026.1 - 0.00082 19.6 0.0 0.0042 17.3 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG79026.1 - 0.0063 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Senescence_reg PF04520.13 GBG79026.1 - 0.83 10.5 5.4 0.29 12.0 2.3 1.8 2 0 0 2 2 2 0 Senescence regulator Nop14 PF04147.12 GBG79028.1 - 0.31 9.2 19.8 0.36 9.0 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG79028.1 - 0.53 9.7 20.6 0.68 9.3 20.6 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG79028.1 - 6.5 4.9 18.2 8.1 4.6 18.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 GBG79028.1 - 9.4 4.2 7.2 10 4.1 7.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DGF-1_5 PF11038.8 GBG79029.1 - 0.054 12.8 1.0 1.2 8.4 1.8 2.2 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 zf-CCHC PF00098.23 GBG79030.1 - 4.5e-07 29.7 1.9 9e-07 28.7 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG79030.1 - 0.002 17.8 1.2 0.0061 16.2 1.2 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Ribosomal_S3_C PF00189.20 GBG79030.1 - 0.028 14.9 0.7 0.2 12.2 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S3, C-terminal domain RT_RNaseH_2 PF17919.1 GBG79031.1 - 1.2e-18 67.0 0.0 2.2e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79031.1 - 1.3e-14 54.4 0.0 3e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79031.1 - 3.4e-10 40.2 0.0 7.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG79031.1 - 0.02 14.7 0.0 0.074 12.8 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Cnd2 PF05786.14 GBG79032.1 - 0.063 11.9 1.0 0.076 11.7 1.0 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 RVT_1 PF00078.27 GBG79034.1 - 4.3e-14 52.6 0.0 6.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG79035.1 - 2.8e-26 92.4 0.1 5.2e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG79035.1 - 1.6e-07 31.8 0.0 5.1e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79035.1 - 2.8e-07 31.0 0.0 1e-06 29.2 0.0 2.1 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG79035.1 - 1.9e-05 24.4 0.0 4.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG79035.1 - 0.00044 20.0 0.0 0.00088 19.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG79035.1 - 0.0016 18.6 6.7 0.0056 16.9 0.1 4.1 4 0 0 4 4 4 1 Retrotransposon gag protein Senescence_reg PF04520.13 GBG79035.1 - 0.012 16.4 1.2 0.055 14.3 1.2 2.2 1 0 0 1 1 1 0 Senescence regulator HIP1_clath_bdg PF16515.5 GBG79035.1 - 0.019 15.6 3.6 0.019 15.6 3.6 3.3 3 1 0 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SPARC_Ca_bdg PF10591.9 GBG79035.1 - 0.099 13.0 0.7 0.41 11.0 0.7 2.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region LMBR1 PF04791.16 GBG79035.1 - 2.3 7.0 3.4 4.7 6.0 3.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Fzo_mitofusin PF04799.13 GBG79035.1 - 6.5 6.3 6.6 20 4.7 2.0 2.9 3 0 0 3 3 3 0 fzo-like conserved region Gp_dh_C PF02800.20 GBG79036.1 - 1.1e-35 122.5 0.0 2.3e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG79036.1 - 1e-13 51.5 0.0 2.2e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF4407 PF14362.6 GBG79036.1 - 0.16 11.3 2.8 0.23 10.8 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF659 PF04937.15 GBG79038.1 - 4.2e-31 107.9 0.0 6.4e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG79038.1 - 9.6e-08 31.7 0.1 2.2e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UPF0561 PF10573.9 GBG79038.1 - 0.0039 17.3 2.8 0.039 14.1 0.0 2.8 2 0 0 2 2 2 1 Uncharacterised protein family UPF0561 DUF4672 PF15716.5 GBG79038.1 - 0.15 11.6 0.3 0.34 10.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) HSP70 PF00012.20 GBG79039.1 - 2.1e-129 432.5 0.0 4.5e-83 279.4 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FGGY_C PF02782.16 GBG79039.1 - 0.00011 22.0 0.2 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.13 GBG79039.1 - 0.00033 19.6 0.1 0.018 13.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 GBG79039.1 - 0.12 11.6 0.1 0.38 10.0 0.1 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase MAGI_u5 PF16666.5 GBG79039.1 - 0.18 12.0 0.1 0.32 11.2 0.1 1.3 1 0 0 1 1 1 0 Unstructured region on MAGI HSP70 PF00012.20 GBG79041.1 - 3.7e-138 461.4 0.0 6.3e-136 454.0 0.0 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG79041.1 - 1.8e-08 33.6 0.0 0.00027 19.9 0.0 3.1 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GBG79041.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG79041.1 - 0.0051 17.2 0.0 1.3 9.5 0.0 2.8 2 0 0 2 2 2 1 Cell division protein FtsA Hydantoinase_A PF01968.18 GBG79041.1 - 0.012 14.8 0.1 0.026 13.8 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase MutL PF13941.6 GBG79041.1 - 0.049 12.2 0.0 0.083 11.5 0.0 1.3 1 0 0 1 1 1 0 MutL protein TraQ PF09679.10 GBG79042.1 - 0.13 12.2 1.4 1.1 9.2 0.1 3.1 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) zf-nanos PF05741.13 GBG79043.1 - 0.0082 16.3 0.0 6 7.2 0.0 3.6 4 0 0 4 4 4 2 Nanos RNA binding domain Strep_pep PF14404.6 GBG79043.1 - 4.3 7.7 13.3 6 7.2 0.3 5.0 3 2 2 5 5 5 0 Ribosomally synthesized peptide in Streptomyces species Integrase_H2C2 PF17921.1 GBG79044.1 - 5.9e-16 58.3 1.7 1.5e-15 57.0 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG79044.1 - 2.6e-12 47.0 0.2 7.9e-12 45.4 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG79044.1 - 2.5e-11 43.3 0.0 5.9e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG79044.1 - 7.1e-08 32.2 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG79044.1 - 2.3e-06 27.7 0.0 7.8e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 H2C2 zinc finger DUF659 PF04937.15 GBG79050.1 - 2.3e-20 73.0 0.1 3.9e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ELYS PF13934.6 GBG79050.1 - 0.06 13.3 0.0 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Nuclear pore complex assembly CCAP PF11105.8 GBG79050.1 - 0.098 12.6 0.3 8.1 6.4 0.0 2.7 3 0 0 3 3 3 0 Arthropod cardioacceleratory peptide 2a TerB PF05099.13 GBG79051.1 - 0.13 12.2 0.5 0.25 11.3 0.5 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB UNC45-central PF11701.8 GBG79051.1 - 0.21 11.5 0.1 0.9 9.5 0.0 2.0 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central TMEM174 PF15029.6 GBG79053.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 174 SDA1 PF05285.12 GBG79059.1 - 0.00078 19.0 13.2 0.0011 18.4 13.2 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG79059.1 - 0.008 14.5 14.4 0.011 14.0 14.4 1.2 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.9 GBG79059.1 - 0.027 13.6 16.2 0.043 13.0 16.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 GBG79059.1 - 0.033 12.5 8.9 0.043 12.1 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.13 GBG79059.1 - 0.15 12.7 2.0 0.55 10.9 0.0 2.3 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HSP90 PF00183.18 GBG79059.1 - 0.78 8.6 9.6 1 8.2 9.6 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF3439 PF11921.8 GBG79059.1 - 1 9.4 7.4 2 8.4 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GBG79059.1 - 3.5 7.6 14.0 1.4 8.9 9.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Na_trans_assoc PF06512.13 GBG79059.1 - 5.2 7.3 18.3 0.48 10.7 13.5 1.7 2 0 0 2 2 2 0 Sodium ion transport-associated eIF-3c_N PF05470.12 GBG79059.1 - 5.2 5.3 6.8 6.9 4.8 6.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Myb_DNA-bind_4 PF13837.6 GBG79060.1 - 4.3e-07 30.2 0.5 8.1e-07 29.3 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG79060.1 - 0.052 13.6 1.4 0.094 12.8 1.4 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG79062.1 - 1.4e-31 109.3 0.0 1.9e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79062.1 - 3.4e-15 56.2 0.0 5.4e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79062.1 - 0.0012 18.6 0.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG79063.1 - 2.7e-25 88.3 0.0 5.4e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79063.1 - 7e-25 87.9 0.2 3.7e-24 85.5 0.0 2.0 1 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79063.1 - 9e-23 80.6 0.0 1.7e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79063.1 - 4.1e-17 62.0 0.8 9.3e-17 60.9 0.8 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG79063.1 - 0.015 15.5 0.0 0.073 13.4 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein rve PF00665.26 GBG79063.1 - 0.026 14.7 0.2 0.077 13.2 0.2 1.9 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 GBG79063.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger dCache_1 PF02743.18 GBG79065.1 - 2.9e-05 24.0 0.7 0.0005 19.9 0.0 2.1 1 1 0 2 2 2 1 Cache domain sCache_3_2 PF17203.4 GBG79065.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 GRP PF07172.11 GBG79065.1 - 7.9 7.2 31.2 17 6.2 31.2 1.5 1 0 0 1 1 1 0 Glycine rich protein family Myb_DNA-bind_4 PF13837.6 GBG79066.1 - 8.4e-10 38.9 1.7 5.3e-09 36.3 1.0 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG79066.1 - 0.45 10.6 6.1 0.13 12.3 2.4 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG79067.1 - 2.6e-30 104.4 0.0 5.1e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79067.1 - 3.4e-30 104.4 0.2 1.2e-29 102.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG79067.1 - 1.2e-29 103.0 0.0 2.7e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79067.1 - 8.7e-14 51.6 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DUF659 PF04937.15 GBG79067.1 - 1.3e-13 51.1 0.0 2.7e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DDE_Tnp_1 PF01609.21 GBG79067.1 - 0.14 11.7 0.2 16 5.0 0.0 2.9 3 0 0 3 3 3 0 Transposase DDE domain RVT_1 PF00078.27 GBG79068.1 - 3.4e-29 102.0 0.0 5.6e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79068.1 - 7.2e-15 54.9 0.0 1.7e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG79068.1 - 1.2e-12 47.6 0.8 1.9e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG79068.1 - 0.00072 19.8 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4360 PF14273.6 GBG79069.1 - 5.1e-31 107.9 0.0 5.8e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG79070.1 - 3.4e-28 98.7 0.0 3.9e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NPCBM_assoc PF10633.9 GBG79070.1 - 0.036 14.3 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF4360 PF14273.6 GBG79072.1 - 4e-26 92.0 0.0 4.6e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NPCBM_assoc PF10633.9 GBG79072.1 - 0.028 14.7 0.1 0.065 13.5 0.0 1.6 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase RT_RNaseH PF17917.1 GBG79073.1 - 1.4e-27 96.1 0.0 3.3e-27 94.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79073.1 - 8e-26 90.0 0.0 1.9e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79073.1 - 1.6e-17 63.8 0.0 3.1e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG79073.1 - 2.3e-15 56.5 0.1 2.8e-14 52.9 0.1 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain eIF-1a PF01176.19 GBG79073.1 - 0.0018 18.1 0.1 0.0037 17.0 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 zf-H2C2 PF09337.10 GBG79073.1 - 0.0021 18.2 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger CCD48 PF15799.5 GBG79073.1 - 0.0071 14.7 2.8 0.011 14.1 2.8 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 rve_3 PF13683.6 GBG79073.1 - 0.012 15.4 0.0 0.045 13.5 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain YscO PF07321.12 GBG79073.1 - 0.059 13.3 7.2 0.23 11.4 7.2 1.9 1 0 0 1 1 1 0 Type III secretion protein YscO DUF2385 PF09539.10 GBG79073.1 - 0.091 13.3 0.3 2 9.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) HALZ PF02183.18 GBG79073.1 - 0.73 10.1 4.5 0.41 10.9 1.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper HSP70 PF00012.20 GBG79075.1 - 3.2e-142 474.8 0.0 3.9e-142 474.5 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG79075.1 - 3e-07 29.6 0.2 2.6e-05 23.2 0.0 2.9 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 GBG79075.1 - 0.005 16.6 1.0 0.018 14.8 0.1 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG79075.1 - 0.076 13.4 0.1 1.1 9.7 0.0 2.7 2 1 0 2 2 2 0 Cell division protein FtsA Myb_DNA-bind_4 PF13837.6 GBG79076.1 - 1.5e-08 34.9 4.3 1.5e-08 34.9 4.3 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG79076.1 - 0.00099 19.3 0.7 0.0028 17.8 0.7 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG79076.1 - 0.004 17.4 3.0 0.012 15.9 1.6 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG79076.1 - 0.012 15.6 1.6 0.028 14.5 1.6 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG79077.1 - 2.6e-07 30.5 0.1 1.5e-06 28.0 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease Integrase_H2C2 PF17921.1 GBG79079.1 - 3.7e-11 43.0 0.1 1.5e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG79079.1 - 3.3e-10 40.2 0.0 9.8e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG79079.1 - 9.9e-06 25.4 0.2 2.3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG79079.1 - 0.00076 19.6 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Glyco_hydro_46 PF01374.18 GBG79080.1 - 4.8e-34 117.8 0.0 6.7e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Myb_DNA-bind_4 PF13837.6 GBG79081.1 - 2e-09 37.7 1.7 3.9e-09 36.8 1.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG79081.1 - 0.00066 20.0 0.8 0.0014 18.9 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG79081.1 - 0.002 18.2 0.5 0.0043 17.1 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG79081.1 - 0.021 15.0 0.4 0.046 13.9 0.4 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2433 PF10360.9 GBG79082.1 - 0.19 11.8 0.0 0.41 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) RT_RNaseH PF17917.1 GBG79083.1 - 2.2e-21 76.1 0.1 4.6e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79083.1 - 6e-17 61.5 0.1 2.3e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG79083.1 - 1.1e-12 47.9 0.0 2.1e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79083.1 - 7.5e-12 45.5 0.0 2.7e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG79083.1 - 2.9e-05 24.2 0.0 6.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG79083.1 - 0.00031 21.0 0.0 0.0012 19.1 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG79083.1 - 0.034 14.8 0.0 0.091 13.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVT_3 PF13456.6 GBG79083.1 - 0.18 11.6 0.1 0.73 9.7 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like AAA_2 PF07724.14 GBG79085.1 - 2.1e-57 193.9 0.1 2.7e-54 183.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GBG79085.1 - 8.1e-37 125.3 1.9 8.1e-37 125.3 1.9 2.3 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 GBG79085.1 - 1e-27 97.2 0.1 1.3e-13 51.5 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GBG79085.1 - 1.7e-21 76.0 0.3 8.1e-21 73.9 0.3 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GBG79085.1 - 1e-18 67.6 0.7 2.8e-12 46.8 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 GBG79085.1 - 1e-15 57.6 4.6 2.3e-07 30.8 0.6 3.3 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 GBG79085.1 - 4.2e-12 46.1 0.0 1.2e-07 31.6 0.0 3.2 2 1 1 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 GBG79085.1 - 3.8e-11 43.7 16.2 5.9e-06 26.8 0.0 5.7 5 2 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 GBG79085.1 - 4.6e-11 43.1 0.1 9.5e-05 22.7 0.0 4.2 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 GBG79085.1 - 8.8e-09 35.3 0.0 0.0014 18.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 GBG79085.1 - 2.1e-07 31.0 0.0 0.04 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GBG79085.1 - 5.8e-07 29.2 0.0 0.0014 18.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 GBG79085.1 - 8.7e-07 29.1 3.4 0.48 10.3 0.1 3.9 4 0 0 4 4 3 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 GBG79085.1 - 1.5e-06 28.8 0.0 0.037 14.6 0.0 3.3 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 GBG79085.1 - 5.9e-05 23.3 0.0 0.063 13.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_3 PF07726.11 GBG79085.1 - 7e-05 22.7 0.0 0.056 13.3 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GBG79085.1 - 7.7e-05 23.0 0.0 0.26 11.7 0.0 3.1 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.12 GBG79085.1 - 8e-05 22.6 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 GBG79085.1 - 8.2e-05 22.4 0.9 0.67 9.7 0.0 4.0 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GBG79085.1 - 9.8e-05 22.5 0.0 0.14 12.3 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GBG79085.1 - 0.00013 22.3 1.7 0.96 9.7 0.0 4.3 2 2 1 3 3 3 2 AAA domain ABC_tran PF00005.27 GBG79085.1 - 0.00018 22.0 0.8 0.12 12.8 0.0 4.0 4 0 0 4 4 3 1 ABC transporter DUF815 PF05673.13 GBG79085.1 - 0.00019 20.7 0.0 0.76 8.9 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) TsaE PF02367.17 GBG79085.1 - 0.00025 21.0 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 GBG79085.1 - 0.00039 20.3 0.0 0.054 13.3 0.0 2.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 GBG79085.1 - 0.0004 19.8 0.0 0.29 10.5 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GBG79085.1 - 0.00046 19.8 1.3 0.061 12.9 0.0 3.8 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 GBG79085.1 - 0.00073 18.9 1.4 0.13 11.5 0.0 3.6 4 0 0 4 4 3 1 Zeta toxin RsgA_GTPase PF03193.16 GBG79085.1 - 0.002 18.1 0.0 2 8.3 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase ResIII PF04851.15 GBG79085.1 - 0.0035 17.4 0.0 0.24 11.4 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GBG79085.1 - 0.0043 16.8 0.2 5.6 6.6 0.2 3.5 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GBG79085.1 - 0.0052 17.1 0.1 0.56 10.5 0.1 3.4 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 GBG79085.1 - 0.0058 16.4 0.0 3.2 7.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain TACC_C PF05010.14 GBG79085.1 - 0.01 15.6 10.3 0.013 15.3 9.0 1.8 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Torsin PF06309.11 GBG79085.1 - 0.014 15.4 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Torsin Bac_DnaA PF00308.18 GBG79085.1 - 0.015 15.1 0.1 4.9 6.9 0.0 3.5 4 0 0 4 4 3 0 Bacterial dnaA protein DUF87 PF01935.17 GBG79085.1 - 0.019 15.1 0.9 0.37 10.9 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain T2SSE PF00437.20 GBG79085.1 - 0.022 13.8 0.0 0.06 12.4 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 GBG79085.1 - 0.023 14.2 0.0 4.3 6.7 0.0 3.3 3 0 0 3 3 3 0 PhoH-like protein NTPase_1 PF03266.15 GBG79085.1 - 0.03 14.2 1.2 9.1 6.2 0.0 3.3 4 0 0 4 4 2 0 NTPase DASH_Spc19 PF08287.11 GBG79085.1 - 0.035 14.0 9.2 0.11 12.4 8.9 2.0 2 0 0 2 2 1 0 Spc19 SRP54 PF00448.22 GBG79085.1 - 0.038 13.6 0.0 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CobU PF02283.16 GBG79085.1 - 0.047 13.3 0.0 3.5 7.2 0.0 3.0 3 0 0 3 3 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase PduV-EutP PF10662.9 GBG79085.1 - 0.052 13.3 0.0 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 GBG79085.1 - 0.057 13.2 0.0 6.2 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GBG79085.1 - 0.072 13.6 10.4 1.1 9.7 0.0 3.5 3 1 0 3 3 3 0 AAA domain Spc7 PF08317.11 GBG79085.1 - 0.11 11.4 9.4 0.19 10.6 9.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Ras PF00071.22 GBG79085.1 - 0.15 11.7 0.1 21 4.6 0.0 2.9 3 0 0 3 3 2 0 Ras family DUF4795 PF16043.5 GBG79085.1 - 0.18 11.4 7.1 6.9 6.2 5.8 3.1 3 1 0 3 3 1 0 Domain of unknown function (DUF4795) DUF573 PF04504.14 GBG79085.1 - 1.7 9.3 7.8 12 6.7 4.5 3.2 3 1 0 3 3 2 0 Protein of unknown function, DUF573 DUF724 PF05266.14 GBG79085.1 - 2.2 8.1 8.6 12 5.7 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Enkurin PF13864.6 GBG79085.1 - 2.8 8.4 9.0 4 7.9 6.7 2.4 2 0 0 2 2 2 0 Calmodulin-binding TbpB_B_D PF01298.18 GBG79086.1 - 0.042 14.3 1.8 0.062 13.7 1.8 1.4 1 1 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B PTRF_SDPR PF15237.6 GBG79086.1 - 0.053 13.1 3.5 0.057 13.0 3.5 1.0 1 0 0 1 1 1 0 PTRF/SDPR family UPF0181 PF03701.14 GBG79086.1 - 0.11 12.1 0.3 9.8 5.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Pox_Ag35 PF03286.14 GBG79086.1 - 0.2 11.4 10.2 0.22 11.3 10.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 GBG79086.1 - 0.91 7.5 23.0 0.96 7.5 23.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG79086.1 - 1.1 7.5 12.9 1.1 7.5 12.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG79086.1 - 1.1 7.3 19.0 1.2 7.3 19.0 1.0 1 0 0 1 1 1 0 Nop14-like family GEMIN8 PF15348.6 GBG79086.1 - 1.3 9.3 7.8 1.6 9.0 7.8 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 TRAP_alpha PF03896.16 GBG79086.1 - 1.8 7.7 8.2 1.7 7.8 8.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 GBG79086.1 - 2.1 7.7 16.8 2.5 7.4 16.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.9 GBG79086.1 - 2.7 7.0 21.6 3.1 6.9 21.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 GBG79086.1 - 3.6 6.9 18.1 3.6 6.9 18.1 1.0 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 GBG79086.1 - 3.6 6.5 12.6 4.1 6.3 12.6 1.0 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 GBG79086.1 - 5.1 6.0 5.2 5.3 5.9 5.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 GBG79086.1 - 5.1 6.3 14.7 5.3 6.3 14.7 1.0 1 0 0 1 1 1 0 BUD22 PIH1 PF08190.12 GBG79087.1 - 5.1e-39 133.4 0.1 6.4e-39 133.1 0.1 1.1 1 0 0 1 1 1 1 PIH1 N-terminal domain Lipocalin_7 PF14651.6 GBG79087.1 - 0.0037 17.2 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF3844 PF12955.7 GBG79087.1 - 1.2 9.2 3.8 8.8 6.5 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3844) DUF3783 PF12646.7 GBG79088.1 - 5.4e-11 42.3 0.2 1e-08 35.0 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF3783) CAP_N PF01213.19 GBG79088.1 - 0.04 13.4 8.8 0.073 12.5 8.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GBG79088.1 - 0.061 13.4 5.8 0.088 12.9 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator EF-hand_7 PF13499.6 GBG79089.1 - 3.1e-13 50.0 0.7 1.7e-12 47.6 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG79089.1 - 2e-11 42.8 1.4 8.3e-05 22.2 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 GBG79089.1 - 2.6e-11 42.5 3.4 0.00016 21.0 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 GBG79089.1 - 7e-11 40.9 3.8 1.4e-05 24.3 0.0 3.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 GBG79089.1 - 6.8e-10 38.7 0.4 2.3e-05 24.1 0.1 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 GBG79089.1 - 0.067 13.2 4.9 5.3 7.0 0.2 3.2 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Menin PF05053.13 GBG79090.1 - 0.87 7.9 3.8 0.96 7.7 3.8 1.0 1 0 0 1 1 1 0 Menin zf-CCHC PF00098.23 GBG79091.1 - 3.7e-08 33.1 3.2 9.7e-08 31.8 3.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG79091.1 - 0.029 14.2 1.3 0.029 14.2 1.3 2.2 2 0 0 2 2 2 0 Zinc knuckle Adeno_E4 PF05385.11 GBG79091.1 - 0.14 12.3 1.4 0.33 11.1 1.4 1.6 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein zf-CCHC_5 PF14787.6 GBG79091.1 - 0.18 11.5 2.8 0.43 10.3 2.8 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger YlaC PF10777.9 GBG79091.1 - 0.49 10.2 2.8 0.57 10.0 0.1 2.3 3 0 0 3 3 3 0 Inner membrane protein YlaC gag-asp_proteas PF13975.6 GBG79093.1 - 1.7e-07 31.7 0.0 2e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG79093.1 - 1.7e-06 27.8 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG79093.1 - 6.2e-05 23.6 0.0 0.00022 21.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG79093.1 - 0.0095 15.7 0.2 0.025 14.4 0.2 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG79093.1 - 0.021 15.1 0.0 1.3 9.3 0.0 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein TcdA_TcdB PF12919.7 GBG79094.1 - 0.15 11.4 0.1 0.94 8.7 0.0 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Trypan_PARP PF05887.11 GBG79094.1 - 1.1 9.3 6.6 3 7.8 6.6 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) K-box PF01486.17 GBG79096.1 - 1.4e-17 63.6 7.6 2.1e-17 63.1 7.6 1.2 1 0 0 1 1 1 1 K-box region PHM7_cyt PF14703.6 GBG79096.1 - 0.047 13.9 1.6 0.67 10.2 0.1 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter ZapB PF06005.12 GBG79096.1 - 0.63 10.5 11.2 0.92 10.0 3.6 2.3 1 1 1 2 2 2 0 Cell division protein ZapB K-box PF01486.17 GBG79097.1 - 1.4e-17 63.6 7.6 2.1e-17 63.0 7.6 1.2 1 0 0 1 1 1 1 K-box region PHM7_cyt PF14703.6 GBG79097.1 - 0.049 13.9 1.6 0.67 10.2 0.1 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter ZapB PF06005.12 GBG79097.1 - 0.63 10.5 11.2 0.93 10.0 3.6 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Chromo PF00385.24 GBG79098.1 - 0.7 9.8 15.2 0.78 9.7 0.2 3.6 3 1 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain SNN_linker PF09050.10 GBG79099.1 - 0.013 15.2 6.2 0.088 12.6 0.5 2.6 2 0 0 2 2 2 0 Stannin unstructured linker CDC45 PF02724.14 GBG79099.1 - 0.091 11.0 23.2 0.13 10.6 23.2 1.2 1 0 0 1 1 1 0 CDC45-like protein GDI PF00996.18 GBG79100.1 - 6.4e-220 730.1 0.1 7.3e-220 729.9 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SH3_14 PF18343.1 GBG79100.1 - 0.015 15.4 0.3 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 Dda helicase SH3 domain XylR_N PF06505.11 GBG79100.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Activator of aromatic catabolism zf-CCCH PF00642.24 GBG79102.1 - 6.7e-13 48.2 11.3 8.8e-08 31.9 3.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 GBG79102.1 - 1.5e-05 24.7 0.0 9.2e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 GBG79102.1 - 0.00025 20.8 10.6 0.0057 16.4 5.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GBG79102.1 - 0.0014 18.6 14.3 0.0022 18.0 4.6 2.5 2 0 0 2 2 2 2 Zinc finger domain Nup35_RRM_2 PF14605.6 GBG79102.1 - 0.22 11.6 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Elong-fact-P_C PF09285.11 GBG79103.1 - 6e-19 67.5 1.0 1.4e-18 66.3 0.2 2.0 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP PF01132.20 GBG79103.1 - 6.1e-15 55.0 0.1 1.2e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.12 GBG79103.1 - 1.5e-12 47.4 0.1 2.5e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain DUF3082 PF11282.8 GBG79104.1 - 4.8e-25 87.6 7.9 4.8e-25 87.6 7.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3082) Retrotrans_gag PF03732.17 GBG79106.1 - 0.0045 17.2 3.2 0.0051 17.1 0.0 2.8 4 0 0 4 4 4 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG79106.1 - 0.034 14.6 0.6 0.44 11.0 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HIP1_clath_bdg PF16515.5 GBG79106.1 - 0.14 12.8 5.3 0.09 13.4 0.8 2.8 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 GBG79106.1 - 0.27 11.3 5.9 0.48 10.5 1.9 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding RVT_1 PF00078.27 GBG79107.1 - 3.1e-28 98.8 0.0 5.4e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79107.1 - 1.3e-26 92.5 0.0 4.2e-26 90.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79107.1 - 6.5e-25 87.5 0.0 1.7e-24 86.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG79107.1 - 5.9e-08 33.3 0.0 3.1e-07 30.9 0.0 2.3 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79107.1 - 8.7e-07 29.4 0.0 2.7e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG79107.1 - 3.1e-06 27.4 0.0 1.1e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG79107.1 - 4.7e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG79107.1 - 0.0092 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Plexin_cytopl PF08337.12 GBG79107.1 - 0.012 14.3 2.4 0.022 13.5 2.4 1.3 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Lipin_mid PF16876.5 GBG79108.1 - 0.1 12.8 1.2 0.85 9.8 0.0 2.6 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain CENP-K PF11802.8 GBG79108.1 - 0.32 10.5 6.4 0.57 9.7 6.4 1.4 1 1 0 1 1 1 0 Centromere-associated protein K PT PF04886.12 GBG79109.1 - 0.0019 17.7 0.7 0.012 15.1 0.7 2.5 1 0 0 1 1 1 1 PT repeat Ferrochelatase PF00762.19 GBG79110.1 - 2.3e-107 358.8 0.0 3e-107 358.4 0.0 1.2 1 0 0 1 1 1 1 Ferrochelatase Chloroa_b-bind PF00504.21 GBG79110.1 - 0.00022 21.8 0.0 0.00048 20.7 0.0 1.5 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CbiX PF01903.17 GBG79110.1 - 0.078 13.3 0.0 18 5.7 0.0 2.5 2 0 0 2 2 2 0 CbiX Ras PF00071.22 GBG79113.1 - 1.4e-45 154.8 0.0 1.7e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG79113.1 - 1.3e-26 93.1 0.0 2e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG79113.1 - 3.3e-12 46.2 0.0 4.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GBG79113.1 - 0.0025 17.9 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pox_A32 PF04665.12 GBG79113.1 - 0.0029 17.1 0.4 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 Poxvirus A32 protein ATP_bind_1 PF03029.17 GBG79113.1 - 0.0056 16.5 0.1 0.22 11.3 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 GBG79113.1 - 0.014 15.5 0.1 0.045 13.9 0.0 2.0 1 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GBG79113.1 - 0.037 13.9 0.0 6.9 6.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 GBG79113.1 - 0.067 12.3 0.1 0.24 10.5 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit TsaE PF02367.17 GBG79113.1 - 0.095 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Gtr1_RagA PF04670.12 GBG79113.1 - 0.12 11.8 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 GBG79113.1 - 0.14 12.7 0.0 0.41 11.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Epimerase PF01370.21 GBG79115.1 - 1.3e-43 149.2 0.0 1.8e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GBG79115.1 - 4.5e-24 85.5 0.0 7.7e-23 81.4 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GBG79115.1 - 2.2e-08 33.4 0.0 3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GBG79115.1 - 1.6e-06 27.5 0.0 8.5e-05 21.8 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 GBG79115.1 - 2.6e-06 27.4 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GBG79115.1 - 2.6e-05 23.5 0.0 0.014 14.5 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GBG79115.1 - 0.014 14.5 0.0 0.067 12.3 0.0 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain PTPRCAP PF15713.5 GBG79116.1 - 0.058 13.7 5.7 0.077 13.3 5.7 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SHR3_chaperone PF08229.11 GBG79116.1 - 0.56 9.1 5.0 0.75 8.7 5.0 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 Radial_spoke PF04712.12 GBG79116.1 - 0.65 8.9 10.5 0.82 8.5 10.5 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein Paf1 PF03985.13 GBG79116.1 - 1.6 7.7 7.5 1.9 7.4 7.5 1.0 1 0 0 1 1 1 0 Paf1 Ribosomal_60s PF00428.19 GBG79116.1 - 2.9 8.6 15.9 4.4 8.0 15.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein TFIIA PF03153.13 GBG79118.1 - 0.069 13.1 16.4 0.096 12.7 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-K PF11802.8 GBG79118.1 - 0.14 11.7 3.9 0.24 11.0 3.9 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Swi6_N PF18530.1 GBG79119.1 - 0.073 13.2 0.1 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Swi6 N-terminal domain ZnuA PF01297.17 GBG79119.1 - 0.075 12.4 0.1 0.076 12.4 0.1 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF659 PF04937.15 GBG79120.1 - 5.8e-17 62.0 0.0 9.6e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG79120.1 - 0.027 14.3 0.2 0.054 13.3 0.2 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RelE PF06296.12 GBG79121.1 - 0.054 13.6 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system CDC27 PF09507.10 GBG79126.1 - 0.81 9.0 34.0 1.1 8.6 34.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RT_RNaseH_2 PF17919.1 GBG79127.1 - 2.2e-28 98.2 0.1 3.5e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79127.1 - 1.6e-26 92.6 0.1 3e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79127.1 - 1.6e-16 60.1 0.7 3.2e-16 59.2 0.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79127.1 - 0.00034 20.8 0.0 0.002 18.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG79127.1 - 0.037 14.2 0.0 0.037 14.2 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger Rab3-GTPase_cat PF13890.6 GBG79127.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit RT_RNaseH PF17917.1 GBG79128.1 - 8.1e-29 100.0 0.1 1.7e-28 98.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79128.1 - 1.3e-27 95.7 0.1 2.7e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79128.1 - 5e-13 49.3 0.2 1.3e-12 47.9 0.2 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG79128.1 - 0.012 15.3 0.1 0.049 13.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Chromo PF00385.24 GBG79128.1 - 0.073 13.0 0.2 0.38 10.7 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG79129.1 - 1.7e-30 105.0 0.0 3.6e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79129.1 - 4e-29 101.7 0.1 8.3e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79129.1 - 6.1e-28 97.2 0.1 1.6e-27 95.9 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79129.1 - 1.7e-14 54.0 0.1 6.2e-14 52.2 0.1 2.0 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG79129.1 - 0.018 15.0 0.5 0.036 14.0 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG79129.1 - 0.24 11.1 1.1 0.67 9.7 0.8 1.9 2 0 0 2 2 2 0 Zinc knuckle CENP-Q PF13094.6 GBG79129.1 - 1.9 8.7 14.3 5.1 7.3 9.3 3.3 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-CCHC PF00098.23 GBG79129.1 - 2.6 8.3 4.9 4.5 7.5 4.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DegQ PF08181.11 GBG79129.1 - 7.5 6.7 5.8 65 3.7 0.1 2.9 2 0 0 2 2 2 0 DegQ (SacQ) family RVT_1 PF00078.27 GBG79131.1 - 3.2e-26 92.2 0.1 7e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79131.1 - 1.2e-24 86.2 0.0 4.1e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79131.1 - 2.3e-20 72.9 0.0 7.3e-20 71.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG79131.1 - 0.0013 19.0 5.9 0.2 11.9 0.0 4.4 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG79131.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease NPV_P10 PF05531.12 GBG79131.1 - 6.7 7.3 7.7 92 3.6 0.7 3.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF659 PF04937.15 GBG79132.1 - 3.5e-34 117.9 0.0 6.1e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) VHP PF02209.19 GBG79132.1 - 0.095 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Villin headpiece domain RVT_1 PF00078.27 GBG79135.1 - 2e-21 76.5 0.0 4.1e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79135.1 - 6.1e-15 55.5 0.1 1.4e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG79135.1 - 4.4e-13 49.1 0.0 9.8e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG79135.1 - 1.7e-06 28.5 0.0 4.9e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79135.1 - 0.00023 21.7 0.0 0.00063 20.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79135.1 - 0.035 13.9 0.0 0.14 11.9 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG79135.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF1478 PF07349.11 GBG79135.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) RVP_2 PF08284.11 GBG79135.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.20 GBG79137.1 - 9.6e-05 22.6 0.1 0.00022 21.5 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG79137.1 - 0.00024 21.6 0.0 0.00047 20.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG79137.1 - 0.00049 20.4 0.0 0.0009 19.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG79137.1 - 0.00068 20.2 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG79137.1 - 0.0036 17.3 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG79137.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease TAF4 PF05236.14 GBG79138.1 - 0.023 14.5 2.2 0.031 14.0 2.2 1.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SMAP PF15477.6 GBG79138.1 - 0.13 13.2 1.0 0.3 12.1 0.5 1.9 2 1 0 2 2 2 0 Small acidic protein family K_channel_TID PF07941.11 GBG79138.1 - 0.3 11.6 4.9 0.67 10.5 4.9 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DnaJ PF00226.31 GBG79139.1 - 8.6e-27 93.1 3.3 2e-26 91.9 3.3 1.7 1 0 0 1 1 1 1 DnaJ domain RT_RNaseH PF17917.1 GBG79139.1 - 1.4e-22 80.0 0.0 3.5e-22 78.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79139.1 - 2.8e-22 78.6 0.0 6.9e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79139.1 - 7.3e-09 35.9 0.0 4e-08 33.5 0.0 2.4 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG79139.1 - 9.5e-08 32.6 0.0 2.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79139.1 - 9.8e-08 31.9 0.0 2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG79139.1 - 1.2e-06 28.5 2.7 2.8e-06 27.3 2.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG79139.1 - 4.7e-06 27.1 0.0 1.2e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG79139.1 - 6.2e-05 23.2 0.3 0.22 11.8 0.0 2.9 2 0 0 2 2 2 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG79139.1 - 0.00041 20.1 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Tudor-knot PF11717.8 GBG79139.1 - 0.0091 15.9 0.0 0.028 14.3 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RVT_1 PF00078.27 GBG79139.1 - 0.018 14.5 0.3 0.12 11.9 0.0 2.4 2 1 1 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3492 PF11997.8 GBG79139.1 - 0.028 14.1 0.3 0.056 13.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DUF4187 PF13821.6 GBG79139.1 - 0.088 12.6 4.4 0.13 12.1 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) SlyX PF04102.12 GBG79139.1 - 2.1 9.0 6.5 1.5 9.5 1.0 3.6 3 0 0 3 3 3 0 SlyX gag-asp_proteas PF13975.6 GBG79140.1 - 0.00029 21.4 0.0 0.00072 20.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79140.1 - 0.021 15.5 0.0 0.043 14.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG79140.1 - 0.046 13.5 0.3 0.082 12.7 0.3 1.3 1 0 0 1 1 1 0 Aspartyl protease SUIM_assoc PF16619.5 GBG79140.1 - 0.22 11.6 2.7 10 6.3 0.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RT_RNaseH_2 PF17919.1 GBG79142.1 - 3.9e-32 110.2 0.1 1.4e-31 108.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79142.1 - 7.7e-29 100.1 0.3 2.7e-28 98.3 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79142.1 - 7.8e-20 70.7 0.1 2.1e-19 69.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG79142.1 - 9.5e-12 44.9 0.4 1.7e-11 44.0 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG79142.1 - 0.00013 22.1 0.0 0.00085 19.5 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG79142.1 - 0.01 16.1 0.0 0.032 14.5 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG79142.1 - 0.012 15.5 1.7 0.038 14.0 1.7 1.8 1 0 0 1 1 1 0 Zinc knuckle NIR_SIR PF01077.22 GBG79142.1 - 0.14 11.6 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain zf-CCHC_4 PF14392.6 GBG79142.1 - 0.15 11.8 0.8 0.39 10.5 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG79142.1 - 0.71 10.1 4.9 2.7 8.2 4.9 2.1 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 GBG79143.1 - 8.7e-07 29.5 0.0 2.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79143.1 - 1e-06 28.6 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG79143.1 - 3.7e-05 24.2 0.0 0.00016 22.1 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG79143.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG79143.1 - 0.0056 16.5 0.0 0.018 14.9 0.0 1.9 1 1 0 1 1 1 1 Aspartyl protease DNA_pack_N PF02500.15 GBG79143.1 - 0.012 15.4 2.9 0.027 14.3 0.0 2.4 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus DNA_pack_N PF02500.15 GBG79144.1 - 0.012 15.5 1.7 0.012 15.5 1.7 2.2 1 1 0 2 2 2 0 Probable DNA packing protein, N-terminus DUF3527 PF12043.8 GBG79144.1 - 1.7 8.2 18.3 0.015 14.9 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) LMBR1 PF04791.16 GBG79144.1 - 4.2 6.2 14.4 7.9 5.3 14.4 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein RNA_polI_A34 PF08208.11 GBG79144.1 - 7.2 6.6 26.3 0.057 13.5 15.7 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3611 PF12263.8 GBG79146.1 - 3.4e-19 69.4 2.7 5.8e-19 68.7 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) DUF4837 PF16125.5 GBG79146.1 - 0.03 13.3 3.4 0.3 10.1 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4837) RseA_C PF03873.13 GBG79146.1 - 0.093 13.0 1.9 4.1 7.7 0.1 2.7 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain CPSF73-100_C PF11718.8 GBG79146.1 - 0.44 10.1 4.6 0.22 11.1 1.6 1.8 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term RT_RNaseH PF17917.1 GBG79147.1 - 5.7e-21 74.8 0.0 1.4e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79147.1 - 4.5e-18 65.6 0.0 1.2e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79147.1 - 1.4e-17 63.5 0.0 3.6e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Tudor-knot PF11717.8 GBG79147.1 - 0.00088 19.1 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Peptidase_C14 PF00656.22 GBG79147.1 - 0.11 12.5 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Caspase domain Retrotrans_gag PF03732.17 GBG79148.1 - 0.0032 17.7 0.1 0.0093 16.2 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein AIP3 PF03915.13 GBG79148.1 - 0.012 14.8 0.4 0.016 14.3 0.4 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 TraD PF06412.11 GBG79148.1 - 0.34 10.8 2.1 12 5.8 0.0 2.8 3 0 0 3 3 3 0 Conjugal transfer protein TraD zf-CCHC PF00098.23 GBG79148.1 - 1.7 8.8 3.8 2.9 8.1 3.8 1.4 1 0 0 1 1 1 0 Zinc knuckle REV PF00424.18 GBG79149.1 - 0.11 12.5 0.4 0.11 12.5 0.4 2.5 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF3138 PF11336.8 GBG79149.1 - 0.11 11.1 0.0 0.23 10.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) Casc1_N PF15927.5 GBG79149.1 - 0.52 10.0 33.1 0.034 13.8 13.5 2.3 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus LMBR1 PF04791.16 GBG79149.1 - 6.4 5.6 4.2 7.6 5.3 4.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4366 PF14283.6 GBG79150.1 - 9.6 6.2 9.7 2.5 8.2 5.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) CW_binding_2 PF04122.12 GBG79151.1 - 0.029 15.0 0.0 0.041 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 DUF659 PF04937.15 GBG79152.1 - 1.5e-07 31.4 0.0 2.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVP PF00077.20 GBG79153.1 - 0.00078 19.7 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG79153.1 - 0.00086 19.8 0.1 0.0021 18.6 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79153.1 - 0.0047 17.5 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease NPBW PF15180.6 GBG79153.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Neuropeptides B and W Asp_protease PF09668.10 GBG79153.1 - 0.093 12.5 0.2 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG79154.1 - 1.9e-23 82.4 0.0 4.4e-23 81.2 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79154.1 - 1.2e-21 76.9 0.0 3.7e-21 75.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG79155.1 - 0.004 17.7 0.1 0.0083 16.7 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG79155.1 - 0.0042 17.4 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG79155.1 - 0.049 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG79155.1 - 0.096 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG79155.1 - 0.12 13.0 0.1 0.3 11.7 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG79158.1 - 4.5e-07 30.3 0.2 9.4e-06 26.1 0.0 2.8 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79158.1 - 1.3e-05 25.7 0.0 8.4e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG79158.1 - 0.027 14.3 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG79158.1 - 0.034 14.2 3.7 0.079 13.1 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Plavaka PF18759.1 GBG79159.1 - 1.5e-20 73.7 0.1 2.8e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Plavaka transposase RVT_1 PF00078.27 GBG79161.1 - 6.3e-23 81.5 0.1 1.2e-22 80.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YabA PF06156.13 GBG79161.1 - 0.025 15.2 0.9 0.052 14.2 0.1 1.9 2 0 0 2 2 2 0 Initiation control protein YabA Cep57_MT_bd PF06657.13 GBG79161.1 - 0.08 13.4 2.3 0.29 11.6 2.1 2.1 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 GCN5L1 PF06320.13 GBG79161.1 - 0.1 12.8 5.2 0.18 12.0 5.2 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) FUSC PF04632.12 GBG79161.1 - 2 6.9 5.0 0.92 8.0 0.2 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family Retrotrans_gag PF03732.17 GBG79162.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG79163.1 - 1.3e-14 54.0 0.1 5.1e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG79163.1 - 0.012 15.9 0.2 0.062 13.6 0.1 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG79163.1 - 0.088 13.0 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC_2 PF13696.6 GBG79163.1 - 6.3 6.7 6.6 0.63 9.9 1.7 1.9 2 0 0 2 2 2 0 Zinc knuckle DDOST_48kD PF03345.14 GBG79164.1 - 5.9e-125 417.3 0.0 6.7e-125 417.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta RVT_1 PF00078.27 GBG79167.1 - 2.4e-06 27.3 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79168.1 - 1.1e-22 80.0 0.0 2.7e-22 78.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79168.1 - 8.8e-22 77.4 0.0 5.8e-21 74.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG79168.1 - 0.028 15.0 0.1 0.083 13.5 0.1 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG79168.1 - 0.087 13.1 0.0 0.37 11.1 0.0 2.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG79168.1 - 0.29 11.4 4.8 0.24 11.7 0.1 2.8 2 1 1 3 3 3 0 Retrotransposon gag protein Toprim_N PF08275.11 GBG79169.1 - 0.001 19.1 7.0 30 4.7 0.0 6.5 1 1 7 8 8 8 0 DNA primase catalytic core, N-terminal domain DCR PF14047.6 GBG79169.1 - 0.0018 18.4 5.8 19 5.5 0.0 5.4 1 1 5 6 6 6 1 Dppa2/4 conserved region SH3_19 PF18597.1 GBG79169.1 - 0.004 16.9 32.5 12 5.8 0.1 8.4 8 0 0 8 8 8 1 Myosin X N-terminal SH3 domain PapC_C PF13953.6 GBG79169.1 - 0.27 11.1 33.1 4.2 7.3 1.5 8.0 2 1 6 9 9 9 0 PapC C-terminal domain Methyltransf_1N PF02870.15 GBG79169.1 - 0.34 11.8 5.9 34 5.4 0.2 4.6 4 1 1 5 5 5 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain MU2_FHA PF18221.1 GBG79169.1 - 0.36 10.9 12.8 16 5.6 0.1 5.7 1 1 6 7 7 7 0 Mutator 2 Fork head associated domain tify PF06200.14 GBG79169.1 - 0.56 9.6 15.1 4.2 6.8 0.2 7.3 9 0 0 9 9 9 0 tify domain RTA1 PF04479.13 GBG79169.1 - 0.94 9.0 11.9 47 3.5 0.0 6.3 2 2 6 8 8 8 0 RTA1 like protein FBA_3 PF08268.12 GBG79169.1 - 2.3 8.2 11.7 13 5.8 2.6 4.1 1 1 4 5 5 5 0 F-box associated domain Integrase_H2C2 PF17921.1 GBG79170.1 - 3.8e-15 55.7 0.6 8.3e-15 54.6 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG79170.1 - 0.0043 17.6 0.0 0.0088 16.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG79170.1 - 0.0081 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG79170.1 - 0.025 15.2 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG79171.1 - 2.8e-22 78.6 0.0 9.5e-22 76.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79171.1 - 6.8e-22 77.8 0.0 1.7e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79171.1 - 1.9e-06 27.5 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4611 PF15387.6 GBG79171.1 - 0.021 15.0 4.0 0.51 10.6 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-CCHC PF00098.23 GBG79172.1 - 0.07 13.2 8.0 0.12 12.5 8.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Prefoldin_2 PF01920.20 GBG79172.1 - 0.084 12.8 0.5 0.084 12.8 0.5 4.9 4 1 1 5 5 5 0 Prefoldin subunit TraC_F_IV PF11130.8 GBG79172.1 - 2.8 7.5 10.6 0.56 9.8 2.9 2.2 1 1 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer zf-CCHC_4 PF14392.6 GBG79172.1 - 3.4 7.5 6.0 7 6.5 6.0 1.6 1 0 0 1 1 1 0 Zinc knuckle PTS_2-RNA PF01885.16 GBG79173.1 - 1.1e-63 214.5 0.0 1.7e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RT_RNaseH_2 PF17919.1 GBG79174.1 - 4.8e-23 81.1 0.0 1.1e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79174.1 - 1.2e-22 80.1 0.0 7.7e-22 77.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG79174.1 - 0.0091 16.5 0.1 0.024 15.2 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79174.1 - 0.024 15.3 0.1 0.064 13.9 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG79174.1 - 0.11 12.8 0.0 0.42 11.0 0.0 2.0 1 0 0 1 1 1 0 Retroviral aspartyl protease IQ PF00612.27 GBG79178.1 - 0.0043 16.7 0.2 0.013 15.3 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif RT_RNaseH_2 PF17919.1 GBG79179.1 - 5.2e-33 113.1 0.0 1.1e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79179.1 - 4.1e-29 100.9 0.4 1.6e-28 99.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79179.1 - 4e-26 91.9 0.0 7.1e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79179.1 - 7.9e-18 64.3 0.3 1.9e-17 63.1 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain EzrA PF06160.12 GBG79179.1 - 0.72 7.9 7.0 1.3 7.2 7.0 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Phage_GPO PF05929.11 GBG79179.1 - 4.2 6.9 8.7 0.75 9.4 0.1 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Snapin_Pallidin PF14712.6 GBG79179.1 - 6.4 7.3 12.6 0.91 10.0 0.7 3.1 1 1 1 2 2 2 0 Snapin/Pallidin RT_RNaseH PF17917.1 GBG79180.1 - 1.9e-05 24.9 0.2 7.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79180.1 - 0.0056 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain SepF PF04472.12 GBG79180.1 - 0.17 12.2 0.1 0.52 10.6 0.1 1.8 1 0 0 1 1 1 0 Cell division protein SepF TP53IP5 PF15331.6 GBG79180.1 - 4 7.5 12.0 7.5 6.6 12.0 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF1754 PF08555.10 GBG79181.1 - 3.2e-13 50.3 17.0 6.2e-10 39.7 7.9 2.4 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) DUF1387 PF07139.11 GBG79181.1 - 0.032 14.0 16.1 0.11 12.3 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) ANAPC_CDC26 PF10471.9 GBG79181.1 - 2.1 9.2 8.2 27 5.7 0.1 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4752 PF15944.5 GBG79181.1 - 3.4 7.8 6.0 11 6.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4752) IHABP4_N PF16174.5 GBG79181.1 - 7.5 7.1 18.5 3.6 8.2 8.3 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF659 PF04937.15 GBG79182.1 - 1e-28 100.2 0.0 1.8e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG79182.1 - 3.9e-26 91.9 0.0 1e-25 90.5 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79182.1 - 1.2e-21 76.9 0.0 4.4e-21 75.1 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79182.1 - 5.4e-21 74.5 0.0 1.7e-20 72.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79182.1 - 4.2e-19 68.4 2.1 1.7e-18 66.4 0.2 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain Dimer_Tnp_hAT PF05699.14 GBG79182.1 - 5.6e-10 38.9 0.1 1.6e-09 37.4 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region rve PF00665.26 GBG79182.1 - 1.8e-08 34.6 0.1 1.1e-07 32.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG79182.1 - 3.9e-06 27.4 0.0 9.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79182.1 - 4.4e-06 26.5 0.0 1.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG79182.1 - 0.00037 21.0 0.0 0.0011 19.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG79182.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG79184.1 - 2.1e-28 99.3 0.1 4.4e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79184.1 - 3.2e-18 65.6 0.3 1.3e-17 63.6 0.3 2.2 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG79184.1 - 1.9e-16 60.2 0.0 4.5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79184.1 - 2.2e-11 44.0 0.1 1.1e-10 41.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG79184.1 - 1e-09 38.3 0.0 3.4e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG79184.1 - 1.5e-05 25.5 0.0 3.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG79184.1 - 0.00024 20.9 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79184.1 - 0.00031 21.3 0.0 0.00072 20.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG79184.1 - 0.0018 18.5 0.2 0.013 15.8 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG79185.1 - 6e-14 51.9 0.2 1.2e-13 51.0 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79185.1 - 2.1e-12 47.3 0.0 4.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Jnk-SapK_ap_N PF09744.9 GBG79185.1 - 0.0006 20.1 2.0 0.0012 19.0 2.0 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 zf-H2C2 PF09337.10 GBG79185.1 - 0.013 15.7 0.4 0.025 14.8 0.4 1.5 1 0 0 1 1 1 0 H2C2 zinc finger TPR_MLP1_2 PF07926.12 GBG79185.1 - 0.035 14.2 7.3 0.079 13.0 7.3 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 GBG79185.1 - 5 6.6 9.5 3.4 7.2 3.1 2.1 2 0 0 2 2 2 0 Intermediate filament protein RVT_1 PF00078.27 GBG79186.1 - 6.9e-19 68.2 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79186.1 - 6.8e-16 58.1 0.0 1.8e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79186.1 - 8.5e-10 38.9 0.1 2.8e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG79186.1 - 8.6e-08 32.4 0.0 2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG79186.1 - 0.00028 20.7 0.0 0.00089 19.0 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG79186.1 - 0.029 14.6 1.4 0.12 12.7 0.1 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG79187.1 - 8.8e-23 80.2 0.0 2.1e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79187.1 - 2.3e-21 76.0 0.0 1.2e-20 73.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79187.1 - 1.3e-19 70.6 0.0 4.7e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79187.1 - 8e-19 67.5 8.2 2.7e-15 56.2 0.5 3.2 3 0 0 3 3 3 2 Integrase zinc binding domain rve PF00665.26 GBG79187.1 - 1.5e-12 47.7 0.0 4.8e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG79187.1 - 2.1e-05 25.0 0.0 7.9e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG79187.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79187.1 - 0.0002 21.9 0.0 0.00052 20.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG79187.1 - 0.0022 18.2 0.3 0.0022 18.2 0.3 2.8 3 0 0 3 3 3 1 H2C2 zinc finger Asp_protease PF09668.10 GBG79187.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Cys_rich_CPXG PF14255.6 GBG79187.1 - 0.034 14.0 1.4 10 6.1 0.0 2.7 2 0 0 2 2 2 0 Cysteine-rich CPXCG Retrotrans_gag PF03732.17 GBG79187.1 - 0.066 13.5 2.0 0.26 11.6 2.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG79188.1 - 8.9e-24 83.4 0.0 1.8e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79188.1 - 2.9e-23 82.1 0.0 6e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79188.1 - 8.7e-23 81.0 0.7 2.2e-22 79.7 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79188.1 - 2.3e-14 53.2 0.7 5e-14 52.2 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79188.1 - 2.7e-07 30.8 0.0 1.1e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG79188.1 - 0.0001 22.1 0.0 0.00036 20.3 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Asp_protease_2 PF13650.6 GBG79188.1 - 0.00016 22.2 0.0 0.00037 21.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79188.1 - 0.00016 22.1 0.0 0.00034 21.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG79188.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG79188.1 - 0.027 14.3 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF35_N PF12172.8 GBG79189.1 - 0.0092 15.8 1.6 0.0092 15.8 1.6 1.9 2 0 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF659 PF04937.15 GBG79190.1 - 5.2e-28 97.8 0.0 8e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG79191.1 - 4.4e-74 244.9 0.0 4.3e-24 84.4 0.0 4.5 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79191.1 - 3.1e-72 239.5 0.0 4.8e-25 87.9 0.0 3.6 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79191.1 - 2.2e-68 230.1 0.2 2.7e-24 85.9 0.1 3.9 4 0 0 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79191.1 - 3.6e-17 62.2 0.5 9.8e-17 60.8 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79191.1 - 7.5e-08 32.6 0.0 3.9e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG79191.1 - 0.089 12.7 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG79191.1 - 0.13 12.1 0.9 0.9 9.5 0.0 2.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Cbl_N PF02262.16 GBG79191.1 - 0.28 11.2 0.7 0.75 9.8 0.2 2.0 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 DUF2917 PF11142.8 GBG79192.1 - 2.3e-05 23.7 26.1 0.93 8.9 0.0 8.0 8 1 0 8 8 8 4 Protein of unknown function (DUF2917) PapC_C PF13953.6 GBG79192.1 - 2.7e-05 23.9 30.6 0.85 9.5 0.2 8.2 1 1 8 10 10 10 5 PapC C-terminal domain DCR PF14047.6 GBG79192.1 - 3.9e-05 23.8 7.0 19 5.6 0.0 7.0 4 3 5 9 9 9 2 Dppa2/4 conserved region MU2_FHA PF18221.1 GBG79192.1 - 0.027 14.5 6.0 29 4.8 0.0 5.5 5 2 1 6 6 6 0 Mutator 2 Fork head associated domain ImpE PF07024.13 GBG79192.1 - 2.2 8.4 14.8 78 3.4 0.1 6.5 3 2 5 9 9 9 0 ImpE protein Gcd10p PF04189.13 GBG79192.1 - 2.7 7.0 5.7 15 4.6 0.1 3.0 3 0 0 3 3 3 0 Gcd10p family tify PF06200.14 GBG79192.1 - 7.1 6.1 13.2 97 2.4 0.0 7.3 10 0 0 10 10 10 0 tify domain RVT_1 PF00078.27 GBG79193.1 - 5.9e-32 111.0 0.0 4.6e-26 91.7 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79193.1 - 7.8e-24 83.6 0.0 2.4e-23 82.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79193.1 - 5.2e-20 71.7 0.0 2.3e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79193.1 - 4e-06 27.0 0.1 3e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG79193.1 - 5.6e-06 26.5 12.2 0.0089 16.3 0.5 4.3 4 0 0 4 4 4 2 Retrotransposon gag protein RNase_E_G PF10150.9 GBG79193.1 - 1.1e-05 25.0 0.1 1.1e-05 25.0 0.1 3.1 2 1 1 3 3 3 1 Ribonuclease E/G family CsgE PF10627.9 GBG79193.1 - 8.5 6.7 10.2 27 5.0 7.2 3.2 2 0 0 2 2 2 0 Curli assembly protein CsgE RT_RNaseH_2 PF17919.1 GBG79194.1 - 2.6e-26 91.6 0.0 6e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79194.1 - 1.9e-24 85.9 0.0 4.7e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79194.1 - 1.1e-19 70.2 0.3 7.6e-19 67.6 0.3 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG79194.1 - 6.7e-08 33.1 0.0 1.7e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79194.1 - 3.9e-07 30.5 0.0 1.2e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG79194.1 - 8.8e-06 25.9 0.0 4e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG79194.1 - 0.00026 20.8 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG79194.1 - 0.00046 19.8 0.0 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG79194.1 - 0.00062 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG79194.1 - 0.0017 18.6 3.8 0.03 14.6 0.0 4.1 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG79194.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger SPACA9 PF15120.6 GBG79194.1 - 0.16 11.7 0.6 0.62 9.8 0.3 2.1 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 RT_RNaseH_2 PF17919.1 GBG79195.1 - 8.6e-30 102.7 0.0 2.6e-29 101.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79195.1 - 2e-29 102.0 0.1 6.6e-29 100.3 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG79195.1 - 4.7e-07 30.0 1.1 0.00021 21.5 0.1 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein SlyX PF04102.12 GBG79195.1 - 2.5 8.8 6.1 6.1 7.5 0.0 4.1 4 0 0 4 4 4 0 SlyX RT_RNaseH_2 PF17919.1 GBG79196.1 - 6.3e-30 103.2 0.0 1.5e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79196.1 - 1.3e-29 102.5 0.1 3.6e-29 101.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG79196.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.6 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH PF17917.1 GBG79197.1 - 4.3e-21 75.2 0.0 8.5e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79197.1 - 4.5e-19 68.3 0.0 8.7e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79197.1 - 6.3e-16 58.2 0.1 1.6e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79197.1 - 3.2e-06 27.3 0.0 7.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79197.1 - 0.0094 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG79198.1 - 9.2e-28 97.3 0.1 1.5e-27 96.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79198.1 - 4.4e-06 26.7 0.0 8.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG79199.1 - 0.00027 20.9 2.1 0.00065 19.7 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG79199.1 - 0.043 13.6 2.5 0.085 12.7 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF5073 PF16817.5 GBG79199.1 - 0.52 10.4 4.1 1.6 8.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5073) zf-C2H2_10 PF16588.5 GBG79199.1 - 1.9 8.3 4.1 0.58 9.9 0.8 1.9 2 0 0 2 2 2 0 C2H2 zinc-finger BT1 PF03092.16 GBG79199.1 - 8.3 4.5 5.8 13 3.9 5.8 1.2 1 0 0 1 1 1 0 BT1 family RVT_1 PF00078.27 GBG79201.1 - 1.7e-29 102.9 0.0 2.3e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_E_G PF10150.9 GBG79202.1 - 2.2e-22 79.8 0.3 2.2e-22 79.8 0.3 1.5 2 0 0 2 2 2 1 Ribonuclease E/G family T2SS_PulS_OutS PF09691.10 GBG79202.1 - 0.021 15.0 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system pilotin lipoprotein (PulS_OutS) FtsL PF04999.13 GBG79202.1 - 0.1 12.6 6.3 5.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Cell division protein FtsL PV-1 PF06637.11 GBG79203.1 - 0.025 13.4 3.8 0.061 12.1 3.8 1.6 1 0 0 1 1 1 0 PV-1 protein (PLVAP) TMF_TATA_bd PF12325.8 GBG79203.1 - 0.028 14.6 4.1 0.12 12.6 4.1 2.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ImpA_N PF06812.12 GBG79203.1 - 0.2 11.8 1.3 0.67 10.1 1.3 1.9 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Bap31_Bap29_C PF18035.1 GBG79203.1 - 0.29 11.2 2.7 0.76 9.8 2.7 1.7 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain YabA PF06156.13 GBG79203.1 - 0.45 11.2 4.3 0.84 10.3 2.8 2.3 2 0 0 2 2 1 0 Initiation control protein YabA DUF1664 PF07889.12 GBG79203.1 - 0.58 10.2 5.8 0.29 11.2 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RPW8 PF05659.11 GBG79203.1 - 0.77 9.4 3.3 1.2 8.8 1.8 2.0 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Prefoldin_2 PF01920.20 GBG79203.1 - 1.4 9.0 6.5 3.6 7.6 4.7 2.4 2 0 0 2 2 2 0 Prefoldin subunit ZapB PF06005.12 GBG79203.1 - 2.5 8.6 5.2 13 6.3 5.2 2.3 1 0 0 1 1 1 0 Cell division protein ZapB AAA_13 PF13166.6 GBG79203.1 - 3.1 6.3 5.4 5.9 5.4 5.4 1.3 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 GBG79203.1 - 5.8 7.0 12.5 17 5.5 12.5 1.8 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 GBG79203.1 - 9.2 6.1 7.7 5.3 6.9 2.0 2.5 2 0 0 2 2 2 0 Septum formation initiator RT_RNaseH_2 PF17919.1 GBG79204.1 - 9.4e-34 115.4 0.1 1.6e-33 114.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79204.1 - 2.4e-31 109.0 0.1 4.1e-31 108.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79204.1 - 5.9e-29 100.4 0.1 1.1e-28 99.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79204.1 - 3.5e-15 55.9 0.1 8.2e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG79204.1 - 6.2e-05 23.5 0.0 0.0002 21.9 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG79204.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79204.1 - 0.0047 17.6 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG79204.1 - 0.055 13.2 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG79204.1 - 0.065 13.5 0.0 0.065 13.5 0.0 2.7 2 0 0 2 2 2 0 H2C2 zinc finger RVT_1 PF00078.27 GBG79205.1 - 3.7e-28 98.6 0.1 5.5e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG79205.1 - 6.1e-07 29.9 0.0 1.3e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79205.1 - 8.9e-07 29.5 0.0 2.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG79205.1 - 2.2e-06 27.6 0.0 8.7e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG79205.1 - 1.8e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79205.1 - 0.00074 19.3 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease APG17 PF04108.12 GBG79205.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Sigma70_ner PF04546.13 GBG79205.1 - 1.1 9.1 9.9 1.8 8.4 3.8 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region BUD22 PF09073.10 GBG79205.1 - 2 7.7 11.5 4 6.7 11.5 1.4 1 0 0 1 1 1 0 BUD22 Es2 PF09751.9 GBG79207.1 - 0.0059 16.4 20.9 0.21 11.3 6.6 2.0 2 0 0 2 2 2 2 Nuclear protein Es2 Muted PF14942.6 GBG79207.1 - 2.6 8.4 32.7 1.9 8.8 11.1 2.5 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF1908 PF08926.11 GBG79207.1 - 3.1 6.8 14.8 0.11 11.6 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) DUF3110 PF11360.8 GBG79207.1 - 5.1 7.4 7.2 2.4 8.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) RT_RNaseH_2 PF17919.1 GBG79208.1 - 1.4e-27 95.7 0.0 4.5e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79208.1 - 8.9e-25 87.0 0.0 2.4e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG79208.1 - 8.8e-05 22.7 1.8 0.00028 21.1 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4596 PF15363.6 GBG79208.1 - 0.075 13.3 1.6 0.32 11.3 1.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) HIP1_clath_bdg PF16515.5 GBG79208.1 - 0.17 12.5 5.0 0.18 12.4 1.9 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Inhibitor_I29 PF08246.12 GBG79208.1 - 0.19 12.2 0.1 0.48 10.9 0.1 1.6 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) DivIC PF04977.15 GBG79208.1 - 2 8.2 3.8 3.7 7.4 0.8 2.4 2 0 0 2 2 2 0 Septum formation initiator zf-CCHC PF00098.23 GBG79209.1 - 4.7e-05 23.3 4.4 7.6e-05 22.6 4.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG79209.1 - 2.1 8.2 3.6 3.7 7.4 3.6 1.4 1 0 0 1 1 1 0 Zinc knuckle FlxA PF14282.6 GBG79209.1 - 3.2 7.8 31.9 0.23 11.5 6.2 4.8 3 1 1 4 4 4 0 FlxA-like protein LPP PF04728.13 GBG79209.1 - 3.8 8.0 8.4 3.8 8.0 0.3 4.3 2 2 1 3 3 3 0 Lipoprotein leucine-zipper PBP_sp32 PF07222.12 GBG79209.1 - 5.9 6.3 15.2 0.19 11.1 1.0 2.8 2 0 0 2 2 2 0 Proacrosin binding protein sp32 IF-2B PF01008.17 GBG79209.1 - 6.5 5.9 7.1 0.95 8.6 1.4 2.2 3 0 0 3 3 3 0 Initiation factor 2 subunit family Laminin_II PF06009.12 GBG79209.1 - 8.3 6.4 16.2 0.23 11.5 1.7 3.3 2 1 1 3 3 3 0 Laminin Domain II DUF1336 PF07059.12 GBG79210.1 - 1.7e-34 119.9 0.0 2.2e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) RT_RNaseH_2 PF17919.1 GBG79211.1 - 3.8e-32 110.3 0.0 1.9e-16 59.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79211.1 - 4.6e-31 107.2 0.0 1e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79211.1 - 5.6e-30 104.5 0.1 8.8e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79211.1 - 4.8e-14 52.2 0.6 1.9e-13 50.3 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG79211.1 - 4.7e-12 45.6 0.0 9.4e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG79211.1 - 0.0001 22.5 0.0 0.00046 20.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79211.1 - 0.0094 16.1 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger START PF01852.19 GBG79213.1 - 2e-17 63.3 0.0 2.8e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 START domain LAP1C PF05609.12 GBG79216.1 - 1.1 8.3 10.0 1.7 7.7 10.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RT_RNaseH PF17917.1 GBG79217.1 - 1.4e-22 80.0 0.0 6.4e-22 77.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79217.1 - 3.7e-21 75.0 0.0 2.1e-19 69.4 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Cpn60_TCP1 PF00118.24 GBG79218.1 - 3.5e-96 322.8 20.7 5.9e-96 322.0 20.7 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family GAF_2 PF13185.6 GBG79218.1 - 0.086 13.1 0.0 4.2 7.7 0.0 2.6 2 0 0 2 2 2 0 GAF domain Nuc_N PF14448.6 GBG79218.1 - 0.24 11.3 4.3 0.96 9.3 0.4 3.6 4 0 0 4 4 4 0 Nuclease N terminal DMRL_synthase PF00885.19 GBG79219.1 - 1.2e-50 171.0 0.1 1.7e-50 170.5 0.1 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RVT_1 PF00078.27 GBG79220.1 - 5.2e-26 91.5 0.5 1.1e-25 90.4 0.2 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79220.1 - 4.9e-19 68.2 0.3 1.1e-18 67.1 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79220.1 - 0.00043 20.5 0.4 0.1 12.8 0.0 2.9 2 1 1 3 3 3 2 Integrase core domain zf-H2C2 PF09337.10 GBG79220.1 - 0.024 14.8 0.0 0.099 12.9 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger Pkinase PF00069.25 GBG79221.1 - 2.1e-43 148.6 0.0 2.9e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79221.1 - 9.9e-43 146.3 0.0 1.4e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 GBG79221.1 - 8.7e-07 28.6 4.9 2.2e-06 27.3 4.9 1.7 1 0 0 1 1 1 1 Leucine rich repeat APH PF01636.23 GBG79221.1 - 0.0019 18.2 0.1 0.03 14.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GBG79221.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PIP49_C PF12260.8 GBG79221.1 - 0.18 11.5 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 LRR_4 PF12799.7 GBG79221.1 - 0.37 11.3 7.6 0.51 10.8 5.5 2.2 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) PCI PF01399.27 GBG79223.1 - 7.9e-13 48.8 0.1 7.9e-13 48.8 0.1 3.2 3 0 0 3 3 3 1 PCI domain Amino_oxidase PF01593.24 GBG79224.1 - 1.1e-57 196.3 0.0 1.9e-57 195.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase RT_RNaseH_2 PF17919.1 GBG79224.1 - 1.2e-27 95.8 0.0 2.5e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79224.1 - 2.3e-25 89.5 0.2 4.8e-25 88.4 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79224.1 - 2.8e-17 62.9 0.0 5.4e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HTH_micro PF17007.5 GBG79224.1 - 0.074 11.9 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 HTH-like Retrotrans_gag PF03732.17 GBG79226.1 - 0.0031 17.7 0.0 0.0082 16.4 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Tetraspanin PF00335.20 GBG79227.1 - 3.1 7.4 15.6 6.2 6.5 5.3 2.4 2 0 0 2 2 2 0 Tetraspanin family RVT_1 PF00078.27 GBG79229.1 - 5.2e-21 75.2 0.2 6e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG79229.1 - 2.7e-11 43.2 0.0 9.5e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG79229.1 - 1.4e-07 31.7 0.0 5.3e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Histone PF00125.24 GBG79230.1 - 7.8e-07 29.5 0.1 1.8e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-CCHC PF00098.23 GBG79231.1 - 2.2e-06 27.5 3.3 3.6e-06 26.8 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG79231.1 - 0.011 15.6 1.8 0.025 14.5 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2895 PF11444.8 GBG79231.1 - 0.028 13.8 1.6 0.052 12.9 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) zf-CCHC_2 PF13696.6 GBG79231.1 - 0.11 12.3 1.0 0.18 11.7 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4192 PF13830.6 GBG79231.1 - 2.6 8.0 5.8 3.7 7.5 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) MGDG_synth PF06925.11 GBG79232.1 - 1.9e-49 168.0 0.0 2.7e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 GBG79232.1 - 1.7e-09 37.8 0.0 2.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 GBG79232.1 - 0.014 15.8 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG79232.1 - 0.15 12.1 0.7 0.56 10.2 0.7 2.1 1 1 0 1 1 1 0 Glycosyltransferase Family 4 DDE_Tnp_4 PF13359.6 GBG79233.1 - 5.2e-20 71.7 0.0 1.1e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79233.1 - 7.3e-05 22.5 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG79234.1 - 4.5e-09 36.6 0.1 9.2e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CDC45 PF02724.14 GBG79235.1 - 0.44 8.8 5.1 0.5 8.6 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 GBG79237.1 - 0.064 13.1 9.9 0.12 12.3 9.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PTRF_SDPR PF15237.6 GBG79237.1 - 0.11 12.1 7.2 0.16 11.5 7.2 1.2 1 0 0 1 1 1 0 PTRF/SDPR family JAB PF01398.21 GBG79237.1 - 0.26 11.3 3.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SDA1 PF05285.12 GBG79237.1 - 0.58 9.5 14.1 0.065 12.7 9.3 1.7 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 GBG79237.1 - 0.66 8.1 13.2 0.95 7.6 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 GBG79237.1 - 0.68 10.4 2.5 1 9.8 2.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 D123 PF07065.14 GBG79237.1 - 0.75 8.9 5.9 2.6 7.1 1.5 2.1 2 0 0 2 2 2 0 D123 CDC45 PF02724.14 GBG79237.1 - 1.3 7.3 9.5 1.9 6.7 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein CDRT4 PF15213.6 GBG79237.1 - 1.3 9.7 0.0 1.3 9.7 0.0 2.1 2 0 0 2 2 1 0 CMT1A duplicated region transcript 4 protein Sporozoite_P67 PF05642.11 GBG79237.1 - 1.3 7.0 4.8 1.7 6.7 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ORC_WH_C PF18137.1 GBG79237.1 - 1.4 9.0 8.4 8.2 6.5 6.3 2.2 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal RRN3 PF05327.11 GBG79237.1 - 1.5 7.3 5.7 2.4 6.6 5.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 GBG79237.1 - 1.7 8.0 12.7 2.6 7.4 12.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Rad54_N PF08658.10 GBG79237.1 - 1.9 8.6 6.6 0.14 12.3 1.3 1.7 2 0 0 2 2 2 0 Rad54 N terminal FAM176 PF14851.6 GBG79237.1 - 3.2 7.4 12.6 0.12 12.0 6.3 1.8 2 0 0 2 2 2 0 FAM176 family TFB6 PF17110.5 GBG79237.1 - 4.1 7.1 6.2 9 6.0 6.2 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4637 PF15470.6 GBG79237.1 - 4.4 7.0 13.9 9.3 5.9 13.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4746 PF15928.5 GBG79237.1 - 8.4 5.7 15.1 16 4.8 15.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2457 PF10446.9 GBG79237.1 - 9.8 5.2 16.2 17 4.4 16.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GBG79237.1 - 10 4.1 19.3 16 3.5 19.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_M50 PF02163.22 GBG79238.1 - 1.3e-07 31.2 4.1 9.1e-05 21.8 0.1 2.5 1 1 1 2 2 2 2 Peptidase family M50 Dicty_REP PF05086.12 GBG79238.1 - 0.31 9.0 0.4 0.43 8.5 0.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AJAP1_PANP_C PF15298.6 GBG79238.1 - 0.56 10.4 5.5 1.2 9.3 5.5 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus MRG PF05712.13 GBG79239.1 - 1e-47 162.1 0.1 1.6e-47 161.4 0.1 1.3 1 0 0 1 1 1 1 MRG DDE_Tnp_4 PF13359.6 GBG79239.1 - 2.6e-22 79.2 0.0 3.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79239.1 - 1.4e-15 57.5 0.0 3.7e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein Tudor-knot PF11717.8 GBG79239.1 - 3e-10 39.8 1.8 5.5e-10 39.0 1.8 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MRG PF05712.13 GBG79240.1 - 9.8e-48 162.1 0.1 1.6e-47 161.4 0.1 1.3 1 0 0 1 1 1 1 MRG DDE_Tnp_4 PF13359.6 GBG79240.1 - 2.6e-22 79.2 0.0 3.8e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79240.1 - 1.4e-15 57.5 0.0 3.6e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein Tudor-knot PF11717.8 GBG79240.1 - 2.9e-10 39.9 1.8 5.5e-10 39.0 1.8 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain K_channel_TID PF07941.11 GBG79240.1 - 1.2 9.6 11.6 6.7 7.3 4.9 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain SH3_9 PF14604.6 GBG79241.1 - 3.3e-11 42.9 0.0 6.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GBG79241.1 - 9.3e-10 38.0 0.0 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GBG79241.1 - 2.1e-08 33.7 0.0 4.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 GBG79241.1 - 3.4e-05 23.7 3.1 5.1e-05 23.1 3.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family DUF4682 PF15733.5 GBG79241.1 - 0.046 14.3 0.5 0.046 14.3 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) NAP PF00956.18 GBG79241.1 - 0.24 10.5 1.0 0.39 9.8 0.2 1.7 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) DUF641 PF04859.12 GBG79241.1 - 0.41 11.0 6.6 2.4 8.5 2.5 3.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Histone PF00125.24 GBG79242.1 - 5.4e-10 39.7 2.9 6.4e-10 39.5 0.1 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 BUD22 PF09073.10 GBG79242.1 - 0.72 9.1 17.3 1.2 8.3 17.3 1.3 1 0 0 1 1 1 0 BUD22 Imm1 PF14430.6 GBG79243.1 - 0.045 14.4 0.0 0.072 13.7 0.0 1.2 1 0 0 1 1 1 0 Immunity protein Imm1 DUF5338 PF17273.2 GBG79244.1 - 0.07 13.2 0.2 15 5.8 0.0 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5338) DNA_pol3_delta2 PF13177.6 GBG79245.1 - 1.5e-12 47.6 0.1 3.1e-12 46.6 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 GBG79245.1 - 6.8e-08 33.0 0.1 2e-07 31.5 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GBG79245.1 - 4.2e-06 26.8 0.0 9e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 GBG79245.1 - 2.4e-05 24.3 0.0 7.6e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 GBG79245.1 - 2.6e-05 24.8 0.0 5.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Sigma54_activ_2 PF14532.6 GBG79245.1 - 0.00013 22.1 0.1 0.00055 20.1 0.1 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 GBG79245.1 - 0.00013 21.9 0.1 0.012 15.6 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 GBG79245.1 - 0.00015 22.2 0.1 0.0016 18.8 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.18 GBG79245.1 - 0.00032 20.6 0.2 0.012 15.4 0.2 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.6 GBG79245.1 - 0.0014 18.9 0.3 0.017 15.4 0.0 2.9 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 GBG79245.1 - 0.0018 17.7 0.0 0.032 13.6 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 GBG79245.1 - 0.002 17.9 0.1 0.0073 16.1 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 GBG79245.1 - 0.0025 17.6 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 GBG79245.1 - 0.0033 17.9 0.0 0.0045 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GBG79245.1 - 0.0043 16.8 0.0 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 GBG79245.1 - 0.014 15.6 0.0 0.035 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 GBG79245.1 - 0.02 14.1 0.0 0.06 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 GBG79245.1 - 0.025 14.5 0.1 0.069 13.1 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Rep_fac_C PF08542.11 GBG79245.1 - 0.035 14.5 0.1 0.12 12.8 0.1 1.9 1 0 0 1 1 1 0 Replication factor C C-terminal domain T2SSE PF00437.20 GBG79245.1 - 0.056 12.5 0.0 0.098 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4085 PF13315.6 GBG79245.1 - 0.078 12.6 0.5 0.19 11.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Sigma54_activat PF00158.26 GBG79245.1 - 0.11 12.2 0.0 17 5.0 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 GBG79245.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain SprT-like PF10263.9 GBG79245.1 - 0.12 12.3 0.2 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 SprT-like family MMR_HSR1_Xtn PF16897.5 GBG79245.1 - 0.12 12.4 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RNA_helicase PF00910.22 GBG79245.1 - 0.14 12.6 0.0 0.6 10.5 0.0 2.2 1 1 0 1 1 1 0 RNA helicase DUF1077 PF06417.12 GBG79246.1 - 1e-34 119.1 0.8 1.4e-34 118.6 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) CRAL_TRIO PF00650.20 GBG79247.1 - 1.4e-30 106.1 0.0 2.4e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GBG79247.1 - 8.4e-11 41.9 0.3 4.4e-10 39.6 0.2 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Herpes_UL17 PF04559.12 GBG79248.1 - 0.71 8.6 4.5 1.1 8.0 4.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein IHABP4_N PF16174.5 GBG79249.1 - 0.014 16.0 1.2 0.014 16.0 1.2 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal FoP_duplication PF13865.6 GBG79249.1 - 3.8 8.1 14.0 4.6 7.9 14.0 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SelK_SelG PF10961.8 GBG79249.1 - 9.8 6.9 13.1 15 6.3 13.1 1.4 1 0 0 1 1 1 0 Selenoprotein SelK_SelG RT_RNaseH_2 PF17919.1 GBG79250.1 - 2.6e-19 69.1 0.1 1.8e-18 66.4 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79250.1 - 2.9e-17 62.9 0.0 5.9e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79250.1 - 1.1e-14 54.6 0.0 5.5e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase PHD PF00628.29 GBG79250.1 - 2.5e-10 40.1 4.9 4.9e-10 39.1 4.9 1.5 1 0 0 1 1 1 1 PHD-finger rve PF00665.26 GBG79250.1 - 1.7e-09 37.9 0.0 4.4e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PHD_2 PF13831.6 GBG79250.1 - 0.0007 19.1 0.6 0.0018 17.8 0.6 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 GBG79250.1 - 0.025 14.5 1.9 0.055 13.4 1.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 GBG79250.1 - 0.038 13.9 1.5 0.09 12.7 1.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.19 GBG79250.1 - 0.13 12.3 4.1 0.46 10.5 4.1 2.0 1 0 0 1 1 1 0 AT hook motif C1_2 PF03107.16 GBG79250.1 - 1.1 9.7 4.4 1 9.7 1.9 2.1 2 0 0 2 2 2 0 C1 domain zf-HC5HC2H PF13771.6 GBG79250.1 - 2.9 8.2 5.1 9.5 6.6 5.1 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain IF4E PF01652.18 GBG79251.1 - 1e-50 171.7 0.0 1.4e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Macoilin PF09726.9 GBG79251.1 - 0.012 14.2 2.2 0.012 14.2 2.2 1.2 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 GBG79251.1 - 0.019 13.8 0.6 0.53 9.0 0.6 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SPX PF03105.19 GBG79251.1 - 5 6.9 11.6 6.6 6.5 11.6 1.2 1 0 0 1 1 1 0 SPX domain Mpv17_PMP22 PF04117.12 GBG79252.1 - 2.7e-16 59.5 0.1 6.4e-16 58.3 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family IMUP PF15761.5 GBG79252.1 - 0.13 13.0 1.7 0.23 12.2 0.1 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein zf-CCHC PF00098.23 GBG79253.1 - 4.4e-05 23.3 5.4 0.00011 22.1 5.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG79253.1 - 0.011 15.6 0.2 0.031 14.2 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG79255.1 - 0.0026 17.5 7.1 0.0054 16.5 7.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG79255.1 - 0.35 11.0 3.9 0.64 10.2 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4407 PF14362.6 GBG79255.1 - 0.4 10.0 4.6 0.53 9.6 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4303 PF14136.6 GBG79255.1 - 1.3 8.8 7.1 2.1 8.1 7.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4303) Radial_spoke_3 PF06098.11 GBG79255.1 - 1.6 7.9 15.2 2.2 7.5 15.2 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 WD40 PF00400.32 GBG79256.1 - 1.6e-19 69.9 16.4 4.3e-05 24.2 0.2 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 GBG79256.1 - 0.0002 20.0 0.1 0.035 12.6 0.0 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 GBG79256.1 - 0.0025 18.1 0.1 8.9 6.7 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 GBG79256.1 - 0.026 14.4 0.4 0.072 13.1 0.4 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat DivIC PF04977.15 GBG79256.1 - 0.03 14.1 0.1 0.12 12.1 0.1 2.1 1 0 0 1 1 1 0 Septum formation initiator PQQ_3 PF13570.6 GBG79256.1 - 0.17 12.4 0.4 1 9.9 0.1 2.5 2 0 0 2 2 2 0 PQQ-like domain RXT2_N PF08595.11 GBG79256.1 - 0.52 10.3 3.8 0.22 11.5 0.6 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 GBG79256.1 - 3.3 5.7 8.6 5.7 4.9 8.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 GBG79256.1 - 5.4 7.2 12.1 0.042 14.1 3.4 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 GBG79256.1 - 9 5.5 12.0 19 4.4 12.0 1.5 1 0 0 1 1 1 0 NOA36 protein Mon1 PF03164.14 GBG79257.1 - 2.2e-95 320.1 0.0 4.8e-64 216.9 0.0 3.6 4 0 0 4 4 4 3 Trafficking protein Mon1 RT_RNaseH_2 PF17919.1 GBG79257.1 - 2.8e-32 110.7 0.0 5.8e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79257.1 - 2.7e-28 99.0 0.0 4.8e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79257.1 - 8.2e-27 93.6 0.0 1.6e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2389 PF09493.10 GBG79257.1 - 0.1 13.2 1.5 0.32 11.7 0.0 2.6 3 0 0 3 3 3 0 Tryptophan-rich protein (DUF2389) UQ_con PF00179.26 GBG79258.1 - 1.4e-27 96.0 0.0 1.7e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Plk4_PB1 PF18190.1 GBG79258.1 - 0.035 14.3 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 RVT_1 PF00078.27 GBG79259.1 - 7.1e-15 55.1 0.1 9.4e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIF_alpha PF05793.12 GBG79259.1 - 0.11 11.0 15.1 0.16 10.5 15.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PLATZ PF04640.14 GBG79259.1 - 0.14 12.8 0.0 0.32 11.7 0.0 1.6 1 0 0 1 1 1 0 PLATZ transcription factor CDC45 PF02724.14 GBG79259.1 - 0.27 9.5 16.1 0.35 9.1 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG79259.1 - 0.35 9.0 21.5 0.45 8.7 21.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG79259.1 - 0.7 9.2 22.0 0.98 8.8 22.0 1.1 1 0 0 1 1 1 0 SDA1 Afi1 PF07792.12 GBG79259.1 - 2.8 8.4 8.9 4.6 7.7 8.9 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Paf1 PF03985.13 GBG79259.1 - 3.1 6.7 21.4 4.5 6.2 21.4 1.2 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.14 GBG79259.1 - 5.7 6.7 13.3 9.5 6.0 13.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.10 GBG79259.1 - 6.1 6.1 23.0 8.4 5.6 23.0 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG79259.1 - 7.6 5.2 9.5 11 4.7 9.5 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_C48 PF02902.19 GBG79260.1 - 1.7e-08 34.6 0.3 3.5e-08 33.6 0.3 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Mak10 PF04112.13 GBG79261.1 - 1.4e-33 115.8 0.0 1.1e-27 96.6 0.0 2.9 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Dpy-30 PF05186.13 GBG79262.1 - 1e-05 25.1 0.2 2.5e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Dpy-30 motif DUF2207 PF09972.9 GBG79262.1 - 0.067 11.9 2.2 0.2 10.4 2.2 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PMEI PF04043.15 GBG79262.1 - 0.5 10.7 5.1 0.94 9.8 0.1 2.6 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor RT_RNaseH_2 PF17919.1 GBG79263.1 - 1.8e-25 88.9 0.0 4.4e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79263.1 - 1e-24 87.3 0.1 1.8e-24 86.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79263.1 - 7.7e-23 80.8 0.0 1.8e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG79265.1 - 2.2e-14 53.6 0.0 4.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Condensin2nSMC PF12422.8 GBG79266.1 - 3.1e-43 147.5 0.1 1.9e-36 125.5 0.0 3.3 3 0 0 3 3 3 2 Condensin II non structural maintenance of chromosomes subunit RVT_1 PF00078.27 GBG79266.1 - 1.9e-31 109.3 0.1 3.2e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79266.1 - 6.3e-30 103.2 0.0 1.3e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79266.1 - 2.1e-25 89.0 0.0 4.3e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79266.1 - 3e-15 56.1 0.1 7.8e-15 54.7 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79266.1 - 5.9e-15 55.5 0.0 1.7e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Adaptin_N PF01602.20 GBG79266.1 - 3.4e-05 22.6 1.9 0.001 17.7 1.9 2.8 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 GBG79266.1 - 0.00014 22.2 0.9 0.35 11.3 0.1 4.6 4 1 0 4 4 4 1 HEAT repeats zf-H2C2 PF09337.10 GBG79266.1 - 0.00017 21.7 0.0 0.0006 20.0 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger HEAT PF02985.22 GBG79266.1 - 0.00025 21.0 2.2 0.081 13.2 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 GBG79266.1 - 0.0037 17.3 6.0 1.6 8.7 0.1 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HBS1_N PF08938.10 GBG79266.1 - 0.077 13.3 0.2 1.8 8.9 0.0 3.0 3 0 0 3 3 3 0 HBS1 N-terminus Sporozoite_P67 PF05642.11 GBG79266.1 - 1.3 7.0 4.2 2 6.4 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RVT_1 PF00078.27 GBG79267.1 - 1.4e-31 109.7 0.1 2.4e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79267.1 - 4.9e-30 103.5 0.0 1e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79267.1 - 1.6e-25 89.4 0.0 3.3e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79267.1 - 2.4e-15 56.4 0.1 6.2e-15 55.1 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79267.1 - 4.3e-15 55.9 0.0 1.3e-14 54.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79267.1 - 0.00014 22.0 0.0 0.00048 20.3 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Condensin2nSMC PF12422.8 GBG79267.1 - 0.00069 19.8 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit Sporozoite_P67 PF05642.11 GBG79267.1 - 1 7.4 4.2 1.5 6.8 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen P3A PF08727.11 GBG79267.1 - 1.3 8.5 3.0 1.9 7.9 0.0 2.8 3 0 0 3 3 3 0 Poliovirus 3A protein like DUF5566 PF17721.1 GBG79268.1 - 0.13 12.5 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5566) Retrotrans_gag PF03732.17 GBG79269.1 - 4.1e-05 23.8 2.1 0.00032 20.9 0.2 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein Glyco_hydro2_C5 PF18565.1 GBG79269.1 - 0.051 13.4 0.3 0.17 11.8 0.3 1.8 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 DUF4407 PF14362.6 GBG79269.1 - 4.1 6.7 20.0 1.1e+02 2.0 20.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) v110 PF01639.17 GBG79272.1 - 0.11 12.4 0.4 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Viral family 110 Pox_D5 PF03288.16 GBG79274.1 - 0.007 16.8 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Nab1 PF04902.12 GBG79274.1 - 0.03 14.7 0.1 0.047 14.1 0.1 1.4 1 1 0 1 1 1 0 Conserved region in Nab1 DUF1397 PF07165.11 GBG79274.1 - 0.11 11.9 0.1 4 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) Cyt-b5 PF00173.28 GBG79275.1 - 4.7e-25 87.5 0.0 6.4e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain VbhA PF18495.1 GBG79275.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Antitoxin VbhA Trypan_PARP PF05887.11 GBG79276.1 - 0.33 10.9 12.1 0.43 10.5 2.0 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Myc_N PF01056.18 GBG79276.1 - 0.46 10.3 2.0 0.65 9.8 2.0 1.4 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.6 GBG79276.1 - 5.4 6.7 7.8 11 5.7 7.8 1.4 1 0 0 1 1 1 0 FAM176 family Thioredoxin PF00085.20 GBG79277.1 - 3.6e-38 129.7 0.1 5.6e-23 80.9 0.2 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 GBG79277.1 - 1.3e-15 57.8 1.0 1.5e-11 44.6 0.1 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 GBG79277.1 - 1.4e-07 31.9 0.8 0.00022 21.6 0.1 3.4 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 GBG79277.1 - 4.9e-06 26.5 0.0 1.5e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 GBG79277.1 - 1.8e-05 24.8 0.1 0.041 14.1 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 GBG79277.1 - 0.00012 21.6 0.5 0.016 14.6 0.1 3.2 3 1 1 4 4 4 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GBG79277.1 - 0.001 19.3 1.0 0.0084 16.4 0.1 2.9 3 2 1 4 4 4 1 Thioredoxin-like Redoxin PF08534.10 GBG79277.1 - 0.0014 18.4 0.1 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 Redoxin HyaE PF07449.11 GBG79277.1 - 0.028 14.4 0.1 0.33 11.0 0.0 2.5 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 GBG79277.1 - 0.033 14.3 0.1 6.1 7.0 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.6 GBG79277.1 - 0.033 14.0 0.1 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 F plasmid transfer operon protein DUF2870 PF11069.8 GBG79278.1 - 2.5e-41 139.9 3.2 2.5e-41 139.9 3.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 GBG79278.1 - 0.069 12.9 0.4 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin family Retrotrans_gag PF03732.17 GBG79279.1 - 0.00012 22.3 0.0 0.00045 20.4 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Endonuc-FokI_C PF09254.11 GBG79279.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal TFIIA PF03153.13 GBG79280.1 - 4.2e-07 30.3 1.5 6.5e-07 29.7 1.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1635 PF07795.11 GBG79280.1 - 0.27 11.0 3.1 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF508 PF04370.12 GBG79280.1 - 2.6 7.8 8.2 5.2 6.8 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) RT_RNaseH_2 PF17919.1 GBG79281.1 - 2.7e-32 110.7 0.0 6.6e-32 109.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79281.1 - 2.8e-27 95.1 0.0 8e-27 93.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79281.1 - 2.5e-24 86.0 0.0 5.4e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79281.1 - 4.1e-16 58.8 0.1 1.2e-15 57.3 0.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG79281.1 - 1.9e-08 34.5 0.0 2.4e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG79281.1 - 0.059 13.6 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Metallophos PF00149.28 GBG79282.1 - 0.00022 21.8 0.6 0.00045 20.8 0.6 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DEK_C PF08766.11 GBG79283.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain PNISR PF15996.5 GBG79284.1 - 0.0014 19.0 7.8 0.0014 19.0 7.8 3.0 4 0 0 4 4 4 1 Arginine/serine-rich protein PNISR Mrpl_C PF18502.1 GBG79284.1 - 0.96 9.8 5.3 0.24 11.7 0.8 2.3 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain RVT_1 PF00078.27 GBG79285.1 - 2e-27 96.1 0.0 4.1e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79285.1 - 3.9e-20 71.7 0.4 1.3e-19 70.1 0.4 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG79285.1 - 3.4e-08 34.0 0.0 9.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79285.1 - 3.1e-07 30.2 0.0 6.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG79285.1 - 6.3e-07 29.9 0.0 1.5e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG79285.1 - 5.3e-06 26.6 0.0 2.2e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG79285.1 - 0.00044 20.0 0.0 0.00077 19.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG79285.1 - 0.015 15.6 10.2 0.018 15.3 0.0 3.8 4 0 0 4 4 4 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG79285.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger LAP1C PF05609.12 GBG79286.1 - 0.66 9.0 15.6 0.75 8.8 15.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PI3K_1B_p101 PF10486.9 GBG79286.1 - 3 5.5 13.8 3.6 5.2 13.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit E3_UFM1_ligase PF09743.9 GBG79287.1 - 5.9e-90 301.6 0.0 8.5e-90 301.1 0.0 1.2 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 FeoC PF09012.10 GBG79287.1 - 0.0051 16.9 0.1 0.47 10.6 0.0 2.7 2 0 0 2 2 2 1 FeoC like transcriptional regulator HTH_24 PF13412.6 GBG79287.1 - 0.042 13.4 0.0 14 5.3 0.0 2.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 GBG79287.1 - 0.069 12.9 0.2 0.93 9.3 0.0 2.6 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain IF3_N PF05198.16 GBG79288.1 - 7.8e-23 80.5 0.1 1.8e-22 79.4 0.1 1.7 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 GBG79288.1 - 5.2e-10 39.1 0.0 8.2e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Usp PF00582.26 GBG79288.1 - 0.0075 16.8 1.1 0.0096 16.4 0.1 1.6 2 0 0 2 2 2 1 Universal stress protein family Metallophos_2 PF12850.7 GBG79289.1 - 1.2e-18 67.9 0.0 1.5e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 GBG79289.1 - 0.029 14.9 0.8 0.29 11.6 0.8 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Beach PF02138.18 GBG79290.1 - 1.2e-120 402.0 0.0 1.8e-120 401.5 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GBG79290.1 - 5.9e-09 35.9 0.4 1.6e-08 34.5 0.4 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Methyltransf_11 PF08241.12 GBG79290.1 - 2.3e-08 34.6 0.0 1e-07 32.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain WD40 PF00400.32 GBG79290.1 - 5.6e-06 27.0 9.9 0.12 13.3 0.2 5.4 5 0 0 5 5 4 1 WD domain, G-beta repeat Methyltransf_25 PF13649.6 GBG79290.1 - 9.7e-05 23.0 0.0 0.00045 20.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Laminin_G_3 PF13385.6 GBG79290.1 - 0.00012 22.2 0.9 0.042 14.0 0.2 2.7 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Methyltransf_12 PF08242.12 GBG79290.1 - 0.00017 22.3 0.0 0.00056 20.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DUF4704 PF15787.5 GBG79290.1 - 0.00024 20.5 4.2 0.22 10.7 0.3 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) Methyltransf_23 PF13489.6 GBG79290.1 - 0.022 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Arm PF00514.23 GBG79290.1 - 0.065 13.3 1.9 6.9 6.9 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ubie_methyltran PF01209.18 GBG79290.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family LSM PF01423.22 GBG79291.1 - 2.9e-07 30.1 0.0 4.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain DivIC PF04977.15 GBG79293.1 - 0.077 12.8 0.5 0.077 12.8 0.5 3.9 4 1 1 5 5 5 0 Septum formation initiator GIT_CC PF16559.5 GBG79293.1 - 0.7 9.8 6.0 4.3 7.3 0.3 2.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 GBG79293.1 - 2.4 8.8 15.2 0.11 13.2 2.2 3.3 1 1 2 3 3 3 0 Initiation control protein YabA DUF2688 PF10892.8 GBG79294.1 - 0.02 14.4 8.5 17 5.0 0.1 5.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2688) DUF4357 PF14267.6 GBG79295.1 - 0.042 13.8 0.1 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) DUF2931 PF11153.8 GBG79295.1 - 0.19 11.4 0.5 0.33 10.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) PseudoU_synth_2 PF00849.22 GBG79296.1 - 2.6e-25 89.4 0.0 6.3e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 RNA pseudouridylate synthase S4 PF01479.25 GBG79296.1 - 1.2e-09 37.7 0.2 3e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 S4 domain SDA1 PF05285.12 GBG79296.1 - 0.025 14.0 12.7 0.037 13.5 12.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG79296.1 - 0.15 10.3 6.3 0.21 9.8 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 GBG79296.1 - 0.29 10.5 12.0 0.5 9.7 12.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT eIF-3c_N PF05470.12 GBG79296.1 - 0.33 9.2 0.9 0.45 8.8 0.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NOA36 PF06524.12 GBG79296.1 - 1.1 8.5 21.9 1.7 7.9 21.9 1.2 1 0 0 1 1 1 0 NOA36 protein FRQ PF09421.10 GBG79296.1 - 1.9 6.4 8.0 2.7 5.9 8.0 1.1 1 0 0 1 1 1 0 Frequency clock protein PPR_2 PF13041.6 GBG79297.1 - 8.4e-69 227.6 0.8 3.9e-13 49.4 0.0 9.7 4 2 6 10 10 10 10 PPR repeat family PPR PF01535.20 GBG79297.1 - 7.4e-64 207.7 24.3 2.4e-06 27.4 0.1 12.0 13 0 0 13 13 13 11 PPR repeat PPR_1 PF12854.7 GBG79297.1 - 5.7e-63 208.3 2.8 3.4e-09 36.3 0.0 11.4 11 0 0 11 11 11 11 PPR repeat PPR_3 PF13812.6 GBG79297.1 - 1.6e-41 140.2 0.0 2.1e-10 40.5 0.0 7.8 6 2 3 9 9 9 6 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG79297.1 - 3.4e-29 101.7 0.2 6e-10 38.9 0.0 5.3 3 1 2 5 5 5 5 Pentacotripeptide-repeat region of PRORP SR-25 PF10500.9 GBG79297.1 - 0.0088 15.7 32.8 0.012 15.2 17.7 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein TPR_14 PF13428.6 GBG79297.1 - 0.011 16.4 21.2 2.2 9.3 0.1 9.3 6 2 5 11 11 11 0 Tetratricopeptide repeat Herpes_pp85 PF04637.12 GBG79297.1 - 1.1 7.6 4.2 2.1 6.7 4.2 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) tRNA-synt_1 PF00133.22 GBG79298.1 - 1.8e-108 363.4 0.0 1.8e-108 363.4 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GBG79298.1 - 4e-27 95.0 0.4 1.9e-26 92.8 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GBG79298.1 - 4.8e-06 25.6 0.0 0.03 13.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GBG79298.1 - 1.2e-05 24.9 0.4 5.7e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 GBG79298.1 - 3.1e-05 23.7 2.3 5.8e-05 22.8 2.3 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS DUF3145 PF11343.8 GBG79298.1 - 0.032 13.8 1.1 0.26 10.8 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3145) 2OG-FeII_Oxy_2 PF13532.6 GBG79298.1 - 0.053 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pkinase_Tyr PF07714.17 GBG79299.1 - 5.5e-47 160.2 0.0 7.3e-46 156.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG79299.1 - 8.7e-46 156.4 0.0 1.4e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Malectin PF11721.8 GBG79299.1 - 4.6e-06 26.8 0.0 0.00018 21.7 0.0 2.4 2 0 0 2 2 2 1 Malectin domain DUF1676 PF07898.13 GBG79299.1 - 0.019 15.0 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) APH PF01636.23 GBG79299.1 - 0.031 14.2 0.2 1.6 8.6 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 GBG79299.1 - 0.068 13.3 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 ABC1 family Pkinase_fungal PF17667.1 GBG79299.1 - 0.07 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ODV-E18 PF10717.9 GBG79299.1 - 0.13 12.2 0.2 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 TMEM154 PF15102.6 GBG79299.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family TsaE PF02367.17 GBG79301.1 - 2.3e-28 98.7 0.0 3.9e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GBG79301.1 - 0.0068 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 GBG79301.1 - 0.093 12.9 0.0 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GBG79301.1 - 0.097 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GBG79301.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GBG79301.1 - 0.23 11.4 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Pkinase_Tyr PF07714.17 GBG79302.1 - 9.2e-12 44.8 0.0 1.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 GBG79302.1 - 1.5e-08 34.8 7.1 8e-05 22.9 0.9 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Pkinase PF00069.25 GBG79302.1 - 3.7e-08 33.0 0.0 6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 GBG79302.1 - 1.2e-07 31.4 10.0 0.00026 20.7 0.5 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 GBG79302.1 - 0.069 13.7 7.0 42 5.3 0.0 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 GBG79302.1 - 2.5 8.4 11.4 2.2 8.5 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase_Tyr PF07714.17 GBG79303.1 - 9.1e-12 44.8 0.0 1.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 GBG79303.1 - 1.5e-08 34.8 7.1 8e-05 22.9 0.9 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Pkinase PF00069.25 GBG79303.1 - 3.7e-08 33.0 0.0 6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 GBG79303.1 - 1.1e-07 31.5 9.9 0.00026 20.7 0.5 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 GBG79303.1 - 0.069 13.7 7.0 41 5.3 0.0 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 GBG79303.1 - 2.4 8.4 11.4 2.2 8.5 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat RT_RNaseH_2 PF17919.1 GBG79304.1 - 2.4e-22 78.8 0.0 4.3e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79304.1 - 3.1e-17 62.8 0.0 7.7e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79304.1 - 0.00055 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG79304.1 - 0.026 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF640 PF04852.12 GBG79305.1 - 1.8e-57 192.9 0.3 2.4e-57 192.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF640) DUF3915 PF13054.6 GBG79307.1 - 3.5 7.6 7.5 1.4 8.9 4.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Novirhabdo_Nv PF05554.11 GBG79308.1 - 0.16 11.7 0.0 4.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein RT_RNaseH PF17917.1 GBG79311.1 - 2.6e-21 75.9 0.0 5.9e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79311.1 - 9.1e-20 70.5 0.1 1.8e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG79311.1 - 2.2e-14 53.3 0.0 7e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79311.1 - 3.4e-10 40.1 0.1 1.5e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG79311.1 - 0.0092 15.9 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-H2C2 PF09337.10 GBG79311.1 - 0.024 14.8 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger SlyX PF04102.12 GBG79311.1 - 2.6 8.7 11.8 0.33 11.6 0.2 3.6 3 0 0 3 3 3 0 SlyX rve PF00665.26 GBG79312.1 - 9.9e-08 32.2 0.0 2.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG79312.1 - 0.11 12.3 0.8 2.7 7.8 0.0 3.4 4 0 0 4 4 4 0 Integrase core domain DUF4407 PF14362.6 GBG79314.1 - 1.9 7.8 10.5 4 6.7 10.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ANTH PF07651.16 GBG79315.1 - 6.7e-94 314.0 0.1 8.4e-94 313.6 0.1 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 GBG79315.1 - 7.7e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain TFIIE-A_C PF11521.8 GBG79317.1 - 2.5 8.4 14.8 1 9.7 1.6 2.6 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Radial_spoke PF04712.12 GBG79317.1 - 2.9 6.7 8.7 4.2 6.2 8.7 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein bZIP_1 PF00170.21 GBG79318.1 - 8e-21 73.9 12.1 2.5e-20 72.3 12.1 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG79318.1 - 1.9e-08 34.2 10.4 1.9e-08 34.2 10.4 3.5 2 1 1 3 3 3 1 Basic region leucine zipper JIP_LZII PF16471.5 GBG79318.1 - 0.0013 18.8 0.4 0.006 16.7 0.4 2.2 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II Mito_fiss_reg PF05308.11 GBG79318.1 - 0.0053 16.9 0.6 0.014 15.5 0.6 1.7 1 0 0 1 1 1 1 Mitochondrial fission regulator HALZ PF02183.18 GBG79318.1 - 0.0077 16.4 0.3 0.24 11.7 0.0 2.4 1 1 1 2 2 2 1 Homeobox associated leucine zipper ZapB PF06005.12 GBG79318.1 - 0.011 16.2 0.3 0.011 16.2 0.3 6.4 3 2 3 6 6 6 0 Cell division protein ZapB ADIP PF11559.8 GBG79318.1 - 0.02 15.0 10.9 0.056 13.5 10.9 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 GBG79318.1 - 0.97 10.1 6.8 0.19 12.4 0.4 3.4 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_Maf PF03131.17 GBG79318.1 - 5.1 7.7 22.9 0.26 11.8 11.1 5.1 2 0 0 2 2 2 0 bZIP Maf transcription factor MFMR PF07777.11 GBG79319.1 - 0.51 10.9 15.1 0.12 12.8 11.4 1.9 1 1 1 2 2 2 0 G-box binding protein MFMR IMUP PF15761.5 GBG79319.1 - 3.6 8.3 9.3 3.3 8.4 7.8 1.6 1 1 1 2 2 2 0 Immortalisation up-regulated protein Ntox1 PF15500.6 GBG79320.1 - 0.14 12.5 4.3 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 DUF4795 PF16043.5 GBG79320.1 - 0.18 11.4 7.6 0.11 12.1 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF1640 PF07798.11 GBG79320.1 - 1.4 8.9 8.3 0.75 9.8 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) APG6_N PF17675.1 GBG79320.1 - 1.7 9.2 16.1 1.9 9.0 4.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4140 PF13600.6 GBG79320.1 - 1.7 9.1 6.6 3.2 8.2 2.8 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MCU PF04678.13 GBG79320.1 - 3 7.9 6.7 0.31 11.1 1.8 1.7 1 1 1 2 2 2 0 Mitochondrial calcium uniporter betaPIX_CC PF16523.5 GBG79320.1 - 4.3 7.2 11.4 0.05 13.4 3.1 1.9 2 0 0 2 2 2 0 betaPIX coiled coil MFMR PF07777.11 GBG79321.1 - 2.8e-15 56.6 18.3 9.7e-15 54.8 18.3 1.9 1 0 0 1 1 1 1 G-box binding protein MFMR bZIP_1 PF00170.21 GBG79321.1 - 4.9e-07 29.7 12.4 8e-07 29.1 12.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor MFMR_assoc PF16596.5 GBG79321.1 - 0.015 15.7 19.0 0.39 11.2 19.0 2.9 1 1 0 1 1 1 0 Disordered region downstream of MFMR bZIP_2 PF07716.15 GBG79321.1 - 0.099 12.7 10.2 0.17 12.0 10.2 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Mito_fiss_reg PF05308.11 GBG79321.1 - 2.4 8.2 12.7 0.024 14.7 3.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF445 PF04286.12 GBG79322.1 - 0.0014 18.6 0.8 0.0017 18.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF2497 PF10691.9 GBG79322.1 - 0.093 13.2 2.5 0.41 11.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) COMPASS-Shg1 PF05205.12 GBG79322.1 - 0.27 12.0 8.9 4.5 8.0 5.2 2.4 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 bZIP_1 PF00170.21 GBG79323.1 - 5.8e-07 29.5 1.3 5.8e-07 29.5 1.3 3.1 2 1 1 3 3 2 2 bZIP transcription factor SDA1 PF05285.12 GBG79323.1 - 8.1e-06 25.5 19.7 8.1e-06 25.5 19.7 1.6 2 0 0 2 2 2 1 SDA1 HALZ PF02183.18 GBG79323.1 - 9.8e-06 25.7 1.1 0.00069 19.8 0.0 2.7 1 1 1 2 2 2 1 Homeobox associated leucine zipper GIT_CC PF16559.5 GBG79323.1 - 6.5e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor CASP_C PF08172.12 GBG79323.1 - 0.0032 16.8 1.9 0.0032 16.8 1.9 2.1 2 0 0 2 2 1 1 CASP C terminal APG6_N PF17675.1 GBG79323.1 - 0.0041 17.6 2.0 0.0041 17.6 2.0 2.4 2 0 0 2 2 1 1 Apg6 coiled-coil region PTPRCAP PF15713.5 GBG79323.1 - 0.0086 16.4 27.4 0.0086 16.4 27.4 2.3 2 0 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated YabA PF06156.13 GBG79323.1 - 0.011 16.4 1.3 0.011 16.4 1.3 2.6 2 0 0 2 2 1 0 Initiation control protein YabA ADIP PF11559.8 GBG79323.1 - 0.016 15.3 3.5 0.016 15.3 3.5 2.4 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding FlhC PF05280.11 GBG79323.1 - 0.039 13.7 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Shugoshin_N PF07558.11 GBG79323.1 - 0.053 13.4 1.3 0.11 12.4 0.4 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Zip PF02535.22 GBG79323.1 - 1.6 7.9 6.8 3.1 6.9 6.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 GBG79323.1 - 1.9 6.7 24.4 0.03 12.6 16.8 1.8 2 0 0 2 2 2 0 CDC45-like protein DDHD PF02862.17 GBG79323.1 - 2 8.5 4.9 4.8 7.3 2.0 2.2 2 0 0 2 2 2 0 DDHD domain RRM_1 PF00076.22 GBG79324.1 - 7.5e-62 205.1 1.3 9.4e-18 63.8 0.1 6.4 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG79324.1 - 0.17 12.1 0.0 1.7 8.9 0.0 2.7 4 0 0 4 4 4 0 RNA recognition motif Dimer_Tnp_hAT PF05699.14 GBG79325.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Pkinase_Tyr PF07714.17 GBG79326.1 - 4.2e-35 121.3 0.0 7.7e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG79326.1 - 2.2e-30 105.9 0.0 7.5e-30 104.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain SGL PF08450.12 GBG79326.1 - 4.1e-05 23.3 0.0 0.13 11.8 0.0 3.0 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GBG79326.1 - 0.0075 16.3 0.0 13 6.1 0.1 4.2 3 0 0 3 3 3 1 NHL repeat Lactonase PF10282.9 GBG79326.1 - 0.053 12.8 0.0 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Pkinase PF00069.25 GBG79327.1 - 2.4e-75 253.3 0.5 9.9e-75 251.3 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain EF-hand_1 PF00036.32 GBG79327.1 - 2e-32 108.3 0.7 2.2e-07 30.0 0.1 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.17 GBG79327.1 - 8.5e-29 100.6 0.1 2e-28 99.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GBG79327.1 - 5.6e-28 97.2 0.5 5.8e-13 49.1 0.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG79327.1 - 9.8e-26 87.5 0.3 7.1e-06 25.5 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GBG79327.1 - 3.4e-22 76.9 0.1 4.5e-06 25.9 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GBG79327.1 - 8.5e-21 73.6 4.9 2.6e-09 36.8 0.0 4.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 GBG79327.1 - 1.1e-08 34.9 0.1 0.0039 17.1 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GBG79327.1 - 7e-08 32.8 0.1 0.0011 19.3 0.1 3.0 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GBG79327.1 - 1.7e-06 28.3 0.1 0.011 16.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.14 GBG79327.1 - 2e-05 24.1 1.7 5.3e-05 22.7 1.7 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EFhand_Ca_insen PF08726.10 GBG79327.1 - 3.5e-05 23.8 0.1 0.22 11.7 0.1 2.6 2 0 0 2 2 2 2 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 GBG79327.1 - 3.6e-05 23.8 0.1 5.2 7.3 0.0 3.4 3 0 0 3 3 3 1 Dockerin type I domain Kinase-like PF14531.6 GBG79327.1 - 0.00059 19.2 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Toprim_2 PF13155.6 GBG79327.1 - 0.0089 16.4 0.2 0.86 10.1 0.0 2.9 1 1 1 2 2 2 1 Toprim-like EF-hand_11 PF08976.11 GBG79327.1 - 0.02 15.8 0.0 2.2 9.2 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain ADH_zinc_N PF00107.26 GBG79328.1 - 4e-16 59.2 0.0 9.1e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GBG79328.1 - 4.7e-10 39.3 0.0 1.4e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GBG79328.1 - 2.1e-06 28.8 0.1 9.2e-06 26.7 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NmrA PF05368.13 GBG79328.1 - 0.0048 16.5 0.6 0.0078 15.8 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family CoA_binding_2 PF13380.6 GBG79328.1 - 0.009 16.5 0.2 0.032 14.7 0.1 1.9 1 1 1 2 2 2 1 CoA binding domain GRP PF07172.11 GBG79329.1 - 0.024 15.3 15.9 0.031 15.0 15.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family BSP_II PF05432.11 GBG79329.1 - 0.42 10.3 29.9 0.47 10.1 29.9 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 GBG79329.1 - 0.51 8.5 16.3 0.54 8.4 16.3 1.0 1 0 0 1 1 1 0 Nop14-like family Sec62 PF03839.16 GBG79329.1 - 1.2 8.6 9.3 1.3 8.5 9.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.14 GBG79329.1 - 1.5 7.1 14.5 1.5 7.1 14.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 GBG79329.1 - 1.7 8.6 16.5 2.2 8.2 16.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Tim54 PF11711.8 GBG79329.1 - 2 7.1 9.2 2.1 7.0 9.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 GBG79329.1 - 3.4 6.3 8.0 3.4 6.3 8.0 1.0 1 0 0 1 1 1 0 Presenilin zf-CCHC PF00098.23 GBG79330.1 - 0.014 15.4 2.6 0.026 14.6 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DAG1 PF05454.11 GBG79330.1 - 0.051 13.0 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) FYTT PF07078.11 GBG79330.1 - 0.41 9.9 6.0 3.2 7.0 0.2 2.2 2 0 0 2 2 2 0 Forty-two-three protein AUDH_Cupin PF18637.1 GBG79330.1 - 0.65 10.0 2.9 4.4 7.3 0.8 2.2 2 0 0 2 2 2 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain Ferlin_C PF16165.5 GBG79330.1 - 0.79 9.7 7.6 1.6 8.7 7.6 1.4 1 0 0 1 1 1 0 Ferlin C-terminus RT_RNaseH_2 PF17919.1 GBG79331.1 - 1.5e-33 114.8 0.1 2.9e-33 113.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79331.1 - 2.6e-28 98.4 0.3 5.1e-28 97.4 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79331.1 - 3e-26 92.3 0.5 6.3e-26 91.3 0.5 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79331.1 - 2.4e-10 40.6 0.1 6.1e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DUF2862 PF11061.8 GBG79331.1 - 0.11 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) DUF5095 PF17016.5 GBG79331.1 - 1.4 8.5 6.5 0.46 10.1 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) RVT_1 PF00078.27 GBG79332.1 - 1e-35 123.3 0.1 1.7e-35 122.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79332.1 - 1.5e-29 102.0 0.0 5.1e-29 100.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79332.1 - 7.6e-29 100.1 0.0 1.8e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG79333.1 - 1.6e-30 105.9 0.0 2.7e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 GBG79333.1 - 1.2e-12 48.1 0.1 4.3e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Plant_tran PF04827.14 GBG79333.1 - 2.4e-12 46.9 0.0 4.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Surp PF01805.20 GBG79333.1 - 3.5e-10 39.7 0.2 1.1e-09 38.1 0.2 1.9 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 GBG79333.1 - 4.9e-09 36.9 0.0 1.3e-08 35.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RVT_1 PF00078.27 GBG79333.1 - 4.7e-08 32.8 0.0 5.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79333.1 - 1.2e-05 25.3 0.1 1.2e-05 25.3 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Sporozoite_P67 PF05642.11 GBG79333.1 - 0.001 17.3 3.7 0.0026 15.9 3.7 1.6 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Chromo PF00385.24 GBG79333.1 - 0.06 13.3 0.5 0.14 12.1 0.5 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DDE_Tnp_1 PF01609.21 GBG79333.1 - 0.34 10.5 5.1 1.5 8.4 0.0 3.2 4 0 0 4 4 4 0 Transposase DDE domain UPF0193 PF05250.11 GBG79334.1 - 2e-11 44.1 0.8 2e-11 44.1 0.8 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0193) Myb_DNA-bind_4 PF13837.6 GBG79334.1 - 1.6e-09 38.0 0.9 2.2e-08 34.3 0.6 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG79334.1 - 0.014 15.5 2.0 0.049 13.7 2.0 2.0 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain HemY_N PF07219.13 GBG79334.1 - 0.09 13.0 1.2 0.23 11.7 1.2 1.7 1 0 0 1 1 1 0 HemY protein N-terminus CD34_antigen PF06365.12 GBG79334.1 - 0.23 11.0 1.0 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 CD34/Podocalyxin family zf-CCHC PF00098.23 GBG79335.1 - 1.5e-05 24.9 3.2 1.5e-05 24.9 3.2 2.8 2 0 0 2 2 2 1 Zinc knuckle Alanine_zipper PF11839.8 GBG79335.1 - 0.096 13.1 24.6 0.25 11.7 24.6 1.7 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein GHMP_kinases_N PF00288.26 GBG79336.1 - 1.9e-13 50.4 1.1 8.9e-13 48.3 1.1 2.3 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GBG79336.1 - 3.6e-08 33.6 0.1 1.1e-07 32.1 0.1 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Glyco_trans_1_3 PF13528.6 GBG79336.1 - 2e-07 30.6 0.1 2e-06 27.3 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 1 GalKase_gal_bdg PF10509.9 GBG79336.1 - 1.4e-05 24.5 0.3 3.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Galactokinase galactose-binding signature Glyco_transf_4 PF13439.6 GBG79336.1 - 0.00082 19.4 0.5 0.0027 17.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GBG79336.1 - 0.0014 19.1 0.3 0.0037 17.7 0.3 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Myb_DNA-bind_4 PF13837.6 GBG79337.1 - 1.4e-08 35.0 0.4 2.7e-08 34.1 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG79337.1 - 0.0067 16.6 0.1 0.018 15.2 0.1 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG79337.1 - 0.028 14.5 0.5 0.056 13.5 0.5 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Herpes_ICP4_N PF03584.15 GBG79337.1 - 0.81 9.5 4.0 1.1 9.1 0.3 2.5 2 1 1 3 3 3 0 Herpesvirus ICP4-like protein N-terminal region DDE_Tnp_4 PF13359.6 GBG79338.1 - 1e-30 106.5 0.0 1.5e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79338.1 - 1.7e-17 63.7 0.0 2.4e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79338.1 - 1.5e-06 28.0 2.9 0.00011 21.9 2.9 2.7 1 1 0 1 1 1 1 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG79339.1 - 3.2e-62 206.8 0.1 4e-31 107.0 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79339.1 - 2.4e-55 185.3 1.1 5.1e-28 97.4 0.2 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79339.1 - 3.3e-45 154.3 1.2 4.1e-31 108.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79339.1 - 1.8e-13 50.3 0.1 4.5e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG79339.1 - 0.00092 19.2 2.6 0.00092 19.2 2.6 3.0 2 0 0 2 2 2 1 Zinc knuckle zf-H2C2 PF09337.10 GBG79339.1 - 0.019 15.2 0.0 0.058 13.6 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF1564 PF07600.11 GBG79339.1 - 0.026 14.2 0.0 0.12 12.1 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) STI1 PF17830.1 GBG79339.1 - 0.13 12.2 0.5 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 STI1 domain zf-CCHC_2 PF13696.6 GBG79339.1 - 0.43 10.4 5.3 1.1 9.2 5.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG79339.1 - 0.7 9.9 3.5 0.32 11.0 0.4 2.1 2 0 0 2 2 2 0 Zinc knuckle E1-E2_ATPase PF00122.20 GBG79340.1 - 7.3e-47 159.2 1.2 7.3e-47 159.2 1.2 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GBG79340.1 - 6.6e-30 105.0 0.6 1.5e-29 103.8 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GBG79340.1 - 0.071 13.6 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GBG79340.1 - 1.8 8.3 3.0 2.1 8.0 1.2 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ion_trans PF00520.31 GBG79341.1 - 2.5e-32 112.1 24.9 3.1e-32 111.7 24.9 1.1 1 0 0 1 1 1 1 Ion transport protein Neur_chan_memb PF02932.16 GBG79341.1 - 0.32 11.0 2.0 1.2 9.1 0.3 2.6 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PKD_channel PF08016.12 GBG79341.1 - 0.42 9.2 23.1 0.55 8.8 14.4 2.2 1 1 1 2 2 2 0 Polycystin cation channel DUF4834 PF16118.5 GBG79341.1 - 3.6 8.6 0.0 3.6 8.6 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) DEK_C PF08766.11 GBG79342.1 - 0.015 15.2 1.4 0.015 15.2 1.4 2.3 2 0 0 2 2 2 0 DEK C terminal domain Ribosomal_60s PF00428.19 GBG79342.1 - 0.023 15.2 4.7 0.023 15.2 4.7 10.7 7 4 3 10 10 10 0 60s Acidic ribosomal protein PRP1_N PF06424.12 GBG79344.1 - 2.2 8.7 19.8 0.061 13.7 11.0 2.1 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal COQ7 PF03232.13 GBG79344.1 - 2.8 7.7 7.4 0.2 11.4 2.7 1.5 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 GSHPx PF00255.19 GBG79345.1 - 6.3e-31 106.2 0.0 1e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 GBG79345.1 - 2.4e-06 27.5 0.7 3.8e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 GBG79345.1 - 0.0042 16.8 0.0 0.0097 15.6 0.0 1.6 2 0 0 2 2 2 1 Redoxin Bd3614-deam PF14439.6 GBG79345.1 - 0.02 15.0 2.0 0.043 13.9 2.0 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase RVT_1 PF00078.27 GBG79346.1 - 1.3e-32 113.1 0.0 2.1e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG79346.1 - 7.8e-12 45.2 0.1 2.2e-11 43.7 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 GBG79346.1 - 3.7e-09 37.2 1.4 2.3e-08 34.6 1.4 2.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 GBG79346.1 - 4.4e-06 26.5 0.0 4.2e-05 23.4 0.0 2.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase HemY_N PF07219.13 GBG79347.1 - 9.2 6.5 7.8 15 5.8 7.8 1.3 1 0 0 1 1 1 0 HemY protein N-terminus RVT_1 PF00078.27 GBG79349.1 - 3.7e-25 88.8 0.1 7e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Apolipoprotein PF01442.18 GBG79349.1 - 0.037 13.9 0.8 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 GBG79349.1 - 0.091 12.9 1.6 0.11 12.5 0.3 1.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 GBG79349.1 - 0.42 10.7 1.7 2.3 8.3 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 GBG79349.1 - 0.78 10.1 6.5 0.25 11.6 2.6 2.3 2 1 0 2 2 2 0 Retrotransposon gag protein FlxA PF14282.6 GBG79349.1 - 2.4 8.2 4.1 13 5.8 0.4 2.4 2 1 0 2 2 2 0 FlxA-like protein Pkinase PF00069.25 GBG79350.1 - 2.4e-70 236.9 0.0 4.2e-70 236.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79350.1 - 2.9e-39 134.9 0.0 5.6e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG79350.1 - 4.1e-12 46.0 0.0 6.1e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GBG79350.1 - 0.00019 20.9 0.7 0.0004 19.8 0.7 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG79350.1 - 0.0011 19.0 0.1 0.0035 17.3 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG79350.1 - 0.014 14.4 0.1 0.027 13.4 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 GBG79351.1 - 2.4e-70 236.9 0.0 4.1e-70 236.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79351.1 - 2.9e-39 134.9 0.0 5.6e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG79351.1 - 4.1e-12 46.0 0.0 6.1e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GBG79351.1 - 0.00019 20.9 0.7 0.0004 19.8 0.7 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG79351.1 - 0.0011 19.0 0.1 0.0035 17.3 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG79351.1 - 0.014 14.4 0.1 0.027 13.4 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 GBG79352.1 - 2.4e-70 236.9 0.0 4.1e-70 236.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79352.1 - 2.9e-39 134.9 0.0 5.6e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG79352.1 - 4.1e-12 46.0 0.0 6.1e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GBG79352.1 - 0.00019 20.9 0.7 0.0004 19.8 0.7 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG79352.1 - 0.0011 19.0 0.1 0.0035 17.3 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG79352.1 - 0.014 14.4 0.1 0.027 13.4 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RT_RNaseH_2 PF17919.1 GBG79354.1 - 1.3e-35 121.4 0.0 3.1e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79354.1 - 3.5e-30 104.4 0.0 7.3e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79354.1 - 4e-28 98.4 0.0 6.7e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79354.1 - 1.4e-15 57.1 0.2 2.9e-15 56.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79354.1 - 6e-09 36.1 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Adaptin_N PF01602.20 GBG79355.1 - 1.2e-73 248.5 0.0 1.7e-44 152.3 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region Alpha_adaptin_C PF02296.16 GBG79355.1 - 2.1e-14 53.7 0.0 4.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 GBG79355.1 - 1.2e-12 48.2 0.0 2.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 GBG79355.1 - 3e-05 24.1 0.0 0.00035 20.7 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 ATP-synt_ab PF00006.25 GBG79355.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NUDIX PF00293.28 GBG79356.1 - 5e-13 49.2 0.1 8.6e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Nudix_N_2 PF14803.6 GBG79356.1 - 1e-10 41.3 0.7 2.4e-10 40.1 0.7 1.7 1 0 0 1 1 1 1 Nudix N-terminal zf-NADH-PPase PF09297.11 GBG79356.1 - 0.0037 16.9 2.4 0.028 14.1 0.1 2.6 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Macoilin PF09726.9 GBG79357.1 - 0.049 12.2 7.5 0.046 12.3 7.5 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 GBG79357.1 - 0.26 10.1 6.9 0.23 10.2 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 GBG79357.1 - 0.37 10.6 7.2 0.36 10.7 7.2 1.1 1 0 0 1 1 1 0 SPX domain LTP_2 PF14368.6 GBG79357.1 - 1 9.5 6.8 0.68 10.1 4.1 2.2 2 0 0 2 2 2 0 Probable lipid transfer SSP160 PF06933.11 GBG79357.1 - 2 6.5 24.7 2.2 6.4 24.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 B12D PF06522.11 GBG79358.1 - 4.1e-21 74.6 0.0 5.1e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit SpoU_methylase PF00588.19 GBG79359.1 - 2.8e-07 30.8 0.0 5.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF2884 PF11101.8 GBG79360.1 - 0.51 9.8 10.2 2.7 7.5 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) XRN_M PF17846.1 GBG79360.1 - 3.9 6.3 15.1 5.4 5.9 15.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Cas_Csy4 PF09618.10 GBG79360.1 - 4.5 7.4 7.3 7.5 6.7 7.3 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) SpoU_methylase PF00588.19 GBG79361.1 - 7.1e-05 23.0 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family Pec_lyase_C PF00544.19 GBG79362.1 - 1.5e-14 54.1 1.9 1.9e-13 50.5 1.9 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG79362.1 - 4.1e-05 23.5 7.9 0.0018 18.2 7.9 2.3 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG79362.1 - 0.022 14.0 0.4 0.022 14.0 0.4 1.7 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 GBG79362.1 - 0.038 13.8 2.3 0.037 13.9 0.9 1.7 2 0 0 2 2 2 0 Pectate lyase superfamily protein Retrotrans_gag PF03732.17 GBG79364.1 - 0.0041 17.4 3.8 0.0069 16.6 0.2 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG79365.1 - 1.8e-26 93.0 0.2 8.8e-26 90.8 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79365.1 - 1.8e-19 69.6 0.4 4.8e-19 68.2 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG79365.1 - 2.1e-08 34.3 0.0 5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79365.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger BLOC1_2 PF10046.9 GBG79365.1 - 0.044 14.1 2.1 0.3 11.4 1.1 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF659 PF04937.15 GBG79367.1 - 4.1e-29 101.4 0.2 7.3e-29 100.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG79367.1 - 9e-08 31.8 0.1 2.2e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pec_lyase_C PF00544.19 GBG79369.1 - 8.5e-17 61.4 0.9 2.2e-15 56.8 0.9 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG79369.1 - 2.5e-07 30.7 5.4 6.7e-07 29.3 4.0 1.9 1 1 1 2 2 2 1 Right handed beta helix region NosD PF05048.13 GBG79369.1 - 0.0015 17.8 0.4 0.0015 17.8 0.4 1.5 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 GBG79369.1 - 0.016 15.0 1.0 0.027 14.3 1.0 1.3 1 0 0 1 1 1 0 Pectate lyase superfamily protein RT_RNaseH_2 PF17919.1 GBG79371.1 - 3e-15 56.1 0.0 5.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79371.1 - 1.1e-14 54.5 0.1 1.5e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79371.1 - 7e-05 23.1 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG79371.1 - 0.07 12.5 15.2 0.088 12.2 15.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG79371.1 - 3.2 7.0 18.6 4.4 6.5 18.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG79371.1 - 6.2 4.9 17.8 8.4 4.5 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG79371.1 - 9.5 4.4 12.7 13 3.9 12.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-bind_4 PF13837.6 GBG79372.1 - 5.2e-07 30.0 3.1 5.3e-07 29.9 0.3 2.3 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG79372.1 - 0.032 14.5 0.2 0.098 13.0 0.2 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVT_1 PF00078.27 GBG79373.1 - 2.9e-28 98.9 0.0 5.1e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG79374.1 - 5.5e-10 39.1 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79374.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein Retrotrans_gag PF03732.17 GBG79375.1 - 0.00025 21.2 1.8 0.0026 18.0 0.1 3.0 3 1 1 4 4 4 1 Retrotransposon gag protein Nodulin-like PF06813.13 GBG79377.1 - 4.4e-49 167.2 13.3 7.7e-49 166.4 13.3 1.4 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 GBG79377.1 - 0.058 12.3 32.7 0.027 13.4 0.8 3.3 2 1 0 3 3 3 0 Major Facilitator Superfamily DUF2070 PF09843.9 GBG79377.1 - 8 4.6 10.3 14 3.8 10.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-CCHC PF00098.23 GBG79378.1 - 4.3e-05 23.4 3.0 8.3e-05 22.5 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle VIGSSK PF14773.6 GBG79378.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.6 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal YtkA PF13115.6 GBG79378.1 - 0.68 10.6 5.6 0.96 10.1 0.5 3.0 3 0 0 3 3 3 0 YtkA-like zf-CCHC_2 PF13696.6 GBG79378.1 - 1.6 8.6 4.1 2.9 7.8 4.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG79379.1 - 5.7e-34 117.2 0.2 8.6e-34 116.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG79379.1 - 0.00035 20.3 0.2 0.00072 19.3 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LSM PF01423.22 GBG79380.1 - 2.2e-17 62.5 0.0 3.8e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 LSM domain Ras PF00071.22 GBG79381.1 - 3.7e-44 150.2 0.0 4.8e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG79381.1 - 3.2e-29 101.6 0.0 5.3e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG79381.1 - 1.2e-10 41.1 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family TsaE PF02367.17 GBG79381.1 - 0.00044 20.2 0.0 0.00082 19.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 GBG79381.1 - 0.0073 15.8 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GBG79381.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 GBG79381.1 - 0.018 15.4 0.0 0.27 11.6 0.0 2.2 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 GBG79381.1 - 0.02 14.4 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.6 GBG79381.1 - 0.021 15.0 0.1 0.037 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 GBG79381.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 GBG79381.1 - 0.1 11.8 1.9 0.56 9.3 0.2 2.5 2 1 1 3 3 3 0 G-protein alpha subunit ATP_bind_1 PF03029.17 GBG79381.1 - 0.14 11.9 0.0 3 7.6 0.0 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein zf-CCHC PF00098.23 GBG79382.1 - 0.00024 21.0 0.1 0.00039 20.3 0.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Presenilin PF01080.17 GBG79382.1 - 1.6 7.4 3.2 2 7.1 3.2 1.0 1 0 0 1 1 1 0 Presenilin HNOBA PF07701.14 GBG79382.1 - 3.3 7.1 6.1 4.2 6.7 5.8 1.3 1 1 0 1 1 1 0 Heme NO binding associated Peptidase_S49_N PF08496.10 GBG79382.1 - 5.9 6.9 8.8 9.2 6.3 8.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SpoIIP PF07454.11 GBG79383.1 - 5.5 6.4 10.2 5.6 6.3 10.2 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 GBG79383.1 - 8.4 5.0 7.4 8.6 5.0 7.4 1.0 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG79385.1 - 3.2e-35 120.2 0.0 5.9e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79385.1 - 2.3e-21 76.1 0.0 5.4e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG79385.1 - 1.5e-05 24.9 0.1 4.2e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 Zinc knuckle WD40 PF00400.32 GBG79386.1 - 4.6e-26 90.6 15.7 9.5e-05 23.1 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG79386.1 - 5.3e-07 29.9 0.7 0.37 11.1 0.1 5.6 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG79386.1 - 9.3e-07 28.1 0.1 0.68 8.8 0.0 4.0 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GBG79386.1 - 0.0003 19.6 1.7 0.0056 15.4 0.7 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 N2227 PF07942.12 GBG79387.1 - 1.1e-89 300.2 0.0 1.7e-89 299.6 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein RVT_1 PF00078.27 GBG79387.1 - 4.3e-30 104.9 0.3 6.3e-29 101.1 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79387.1 - 1.9e-22 79.1 0.0 4e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79387.1 - 4.1e-22 78.5 0.0 8e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG79387.1 - 1.1e-08 34.9 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79387.1 - 5.4e-06 27.0 0.0 2.2e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79387.1 - 2e-05 25.0 0.0 4.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4106 PF13388.6 GBG79387.1 - 0.011 15.1 2.0 0.091 12.0 2.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4106) Asp_protease PF09668.10 GBG79387.1 - 0.024 14.4 0.0 0.081 12.7 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease APG17 PF04108.12 GBG79387.1 - 0.11 11.6 0.0 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 Autophagy protein Apg17 Fe_bilin_red PF05996.12 GBG79388.1 - 4.2e-40 137.8 0.1 5e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase KNOX2 PF03791.13 GBG79388.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 KNOX2 domain RNA_pol_3_Rpc31 PF11705.8 GBG79389.1 - 0.0087 16.3 13.0 0.0087 16.3 13.0 3.7 2 1 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 GIY-YIG PF01541.24 GBG79389.1 - 0.048 13.9 0.0 0.31 11.3 0.0 2.3 2 1 0 2 2 2 0 GIY-YIG catalytic domain HypD PF01924.16 GBG79389.1 - 0.16 11.0 0.3 0.25 10.4 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Prothymosin PF03247.14 GBG79389.1 - 0.6 10.6 63.9 0.02 15.3 23.1 4.2 4 0 0 4 4 4 0 Prothymosin/parathymosin family rve PF00665.26 GBG79390.1 - 2.9e-13 50.1 0.0 7.7e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG79390.1 - 0.002 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) RT_RNaseH PF17917.1 GBG79390.1 - 0.015 15.6 0.1 0.044 14.1 0.1 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase SIMPL PF04402.14 GBG79390.1 - 3.4 8.1 10.4 0.2 12.1 3.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF541) Peripla_BP_2 PF01497.18 GBG79391.1 - 4.2e-17 62.5 0.0 7e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein DUF5522 PF17653.1 GBG79391.1 - 3.4e-11 42.9 5.6 6.6e-11 42.0 5.6 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Na_Ca_ex PF01699.24 GBG79392.1 - 6.3e-31 107.4 22.6 2.4e-17 63.3 7.6 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein gag-asp_proteas PF13975.6 GBG79393.1 - 1.6e-08 34.9 0.2 1.7e-07 31.7 0.1 2.3 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79393.1 - 2.4e-06 28.1 0.2 6.4e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79393.1 - 5.3e-05 23.0 0.1 8.7e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79393.1 - 0.0046 16.7 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease MLTR_LBD PF17765.1 GBG79393.1 - 0.088 12.9 0.2 12 6.0 0.0 2.2 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain Elf4 PF07011.11 GBG79397.1 - 6.2e-26 90.1 0.3 1.5e-25 88.9 0.3 1.6 1 0 0 1 1 1 1 Early Flowering 4 domain DDE_Tnp_4 PF13359.6 GBG79397.1 - 2.2e-13 50.2 0.0 4.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79397.1 - 9.8e-08 31.8 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79397.1 - 0.0064 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain RVT_1 PF00078.27 GBG79398.1 - 9.7e-08 31.8 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 GBG79400.1 - 1.5e-16 60.4 0.7 0.00028 21.6 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG79400.1 - 8.7e-07 29.2 0.0 0.078 13.3 0.0 3.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG79400.1 - 0.057 12.1 0.0 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40 PF00400.32 GBG79401.1 - 2.8e-17 62.7 1.5 0.00031 21.5 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG79401.1 - 7.1e-08 32.6 0.0 0.087 13.1 0.0 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG79401.1 - 0.062 11.9 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PAP2 PF01569.21 GBG79402.1 - 2.6e-18 66.1 7.3 6e-18 64.9 7.3 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 GBG79402.1 - 5.1e-05 23.1 14.1 0.0001 22.1 3.7 2.8 2 1 0 2 2 2 2 PAP2 superfamily PAP2_C PF14360.6 GBG79402.1 - 0.0086 16.6 2.3 0.0086 16.6 2.3 2.5 3 0 0 3 3 3 1 PAP2 superfamily C-terminal Cyclin_C_2 PF16899.5 GBG79403.1 - 1.8e-11 44.4 0.0 1.4e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 GBG79403.1 - 2.3e-10 40.3 0.0 4.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 GBG79403.1 - 3.4e-06 27.0 0.0 6.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat PikAIV_N PF18605.1 GBG79403.1 - 0.37 10.4 0.1 0.37 10.4 0.1 2.1 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain AA_kinase PF00696.28 GBG79404.1 - 2e-28 99.6 0.0 8.1e-23 81.3 0.0 2.3 1 1 1 2 2 2 2 Amino acid kinase family ACT PF01842.25 GBG79404.1 - 1.2e-11 44.2 0.4 8.7e-06 25.4 0.0 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 GBG79404.1 - 3.4e-06 26.7 1.4 0.016 15.0 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_5 PF13710.6 GBG79404.1 - 0.027 14.3 0.2 0.49 10.3 0.0 2.4 2 1 0 2 2 2 0 ACT domain MarR_2 PF12802.7 GBG79404.1 - 0.062 13.2 0.1 4.4 7.3 0.0 2.8 3 0 0 3 3 3 0 MarR family AA_kinase PF00696.28 GBG79405.1 - 2.6e-28 99.2 0.0 9.4e-23 81.0 0.0 2.3 1 1 1 2 2 2 2 Amino acid kinase family ACT PF01842.25 GBG79405.1 - 1.6e-11 43.8 0.4 9.9e-06 25.2 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 GBG79405.1 - 4.9e-06 26.2 1.4 0.018 14.8 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT_5 PF13710.6 GBG79405.1 - 0.034 14.0 0.2 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 ACT domain MarR_2 PF12802.7 GBG79405.1 - 0.11 12.3 0.0 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 MarR family Lysine_decarbox PF03641.14 GBG79406.1 - 2.1e-38 131.4 0.0 2.8e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 GBG79406.1 - 4.4e-12 45.9 1.7 2.6e-11 43.4 1.4 2.0 1 1 1 2 2 2 1 SLOG cluster4 family Sde2_N_Ubi PF13019.6 GBG79407.1 - 2e-26 92.8 2.5 2e-26 92.8 2.5 2.6 1 1 1 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Telomere_Sde2_2 PF13297.6 GBG79407.1 - 7.5e-24 83.1 2.9 1.5e-23 82.2 2.9 1.5 1 0 0 1 1 1 1 Telomere stability C-terminal ubiquitin PF00240.23 GBG79407.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family TP53IP5 PF15331.6 GBG79410.1 - 2.9 8.0 11.7 4.5 7.4 11.7 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PA26 PF04636.13 GBG79410.1 - 3.1 6.6 10.7 4.1 6.2 10.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RVT_1 PF00078.27 GBG79412.1 - 2.1e-12 47.0 0.0 3.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AA_kinase PF00696.28 GBG79413.1 - 7.4e-10 38.8 0.4 2.6e-05 24.0 0.0 2.3 1 1 1 2 2 2 2 Amino acid kinase family DAP_epimerase PF01678.19 GBG79413.1 - 2.6e-06 27.6 0.0 8.9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Diaminopimelate epimerase SNF2_N PF00176.23 GBG79414.1 - 1.4e-66 224.7 0.5 2.9e-66 223.6 0.5 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG79414.1 - 4.7e-19 68.8 0.0 1.4e-18 67.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.6 GBG79414.1 - 2.2e-10 41.0 2.6 2.2e-10 41.0 2.6 6.0 5 1 1 6 6 6 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 GBG79414.1 - 1.9e-08 34.5 0.0 8.7e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GBG79414.1 - 4e-05 22.9 0.5 0.00015 21.1 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 CitMHS PF03600.16 GBG79416.1 - 5.4e-18 65.2 10.7 5.4e-18 65.2 10.7 1.7 1 1 0 1 1 1 1 Citrate transporter ArsB PF02040.15 GBG79416.1 - 0.00014 21.4 8.5 0.00019 20.9 8.5 1.1 1 0 0 1 1 1 1 Arsenical pump membrane protein TAF4 PF05236.14 GBG79417.1 - 0.049 13.4 8.7 0.053 13.3 8.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CDC27 PF09507.10 GBG79417.1 - 0.17 11.3 16.5 0.2 11.0 16.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ORC6 PF05460.13 GBG79417.1 - 0.17 11.1 4.7 0.19 10.9 4.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Dicty_REP PF05086.12 GBG79417.1 - 3.2 5.6 6.7 4 5.3 6.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF755 PF05501.11 GBG79417.1 - 3.6 7.9 13.0 5.9 7.2 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) HHV6-IE PF03753.13 GBG79417.1 - 5.1 4.4 11.8 6.6 4.1 11.8 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Presenilin PF01080.17 GBG79417.1 - 8.6 5.0 6.1 9.8 4.8 6.1 1.1 1 0 0 1 1 1 0 Presenilin Integrase_H2C2 PF17921.1 GBG79418.1 - 3.1e-13 49.6 0.1 6.8e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG79418.1 - 1.3e-08 35.3 0.0 4.5e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79418.1 - 1.1e-05 26.0 0.0 3.3e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease rve PF00665.26 GBG79418.1 - 1.7e-05 25.0 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG79418.1 - 0.00024 20.7 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG79418.1 - 0.0038 17.0 0.6 0.0074 16.1 0.6 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG79418.1 - 0.0099 16.2 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease ZapB PF06005.12 GBG79419.1 - 0.0042 17.5 0.1 0.0042 17.5 0.1 3.2 2 1 0 2 2 2 1 Cell division protein ZapB DUF1664 PF07889.12 GBG79419.1 - 0.084 12.9 0.7 0.4 10.7 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4455 PF14643.6 GBG79420.1 - 7.1e-16 57.9 5.9 9.5e-16 57.5 5.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) Cortex-I_coil PF09304.10 GBG79420.1 - 0.016 15.4 1.1 0.03 14.5 0.9 1.5 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF4455 PF14643.6 GBG79421.1 - 5.1e-24 84.8 4.8 5.8e-24 84.6 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) SH3_3 PF08239.11 GBG79422.1 - 0.032 14.5 0.1 0.077 13.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial SH3 domain DUF3139 PF11337.8 GBG79423.1 - 5.4 7.8 5.2 3.9 8.2 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) RR_TM4-6 PF06459.12 GBG79423.1 - 6 6.6 14.2 9 6.0 14.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 GBG79423.1 - 6.2 3.8 6.7 7 3.6 6.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 GBG79424.1 - 1.2 9.1 2.4 2 8.4 2.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RVT_1 PF00078.27 GBG79425.1 - 2.7e-28 99.0 0.1 4.4e-28 98.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79425.1 - 3.2e-25 88.1 0.0 7.8e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79425.1 - 8.2e-24 83.9 0.0 1.5e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79425.1 - 1.5e-15 57.0 0.2 1.3e-14 54.0 0.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG79425.1 - 0.0018 18.5 0.0 0.0044 17.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrin_b_cyt PF08725.11 GBG79425.1 - 0.099 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Herpes_BLRF2 PF05812.12 GBG79426.1 - 0.0082 16.3 0.5 0.0082 16.3 0.5 1.9 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein Baculo_PEP_C PF04513.12 GBG79426.1 - 0.15 12.1 4.5 1.2 9.2 4.5 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_TM PF12794.7 GBG79426.1 - 1.3 7.8 3.9 2.5 6.9 3.9 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 CSTF2_hinge PF14327.6 GBG79428.1 - 0.021 15.3 0.6 0.036 14.5 0.6 1.3 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DUF4375 PF14300.6 GBG79428.1 - 0.088 13.1 10.3 0.17 12.2 10.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) FAM60A PF15396.6 GBG79428.1 - 0.57 10.1 9.4 0.62 10.0 9.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TRAP_alpha PF03896.16 GBG79428.1 - 3.5 6.7 8.3 4.5 6.4 8.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PA26 PF04636.13 GBG79428.1 - 7.4 5.4 13.2 8.9 5.1 13.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Phage_int_SAM_1 PF02899.17 GBG79429.1 - 0.011 16.0 0.9 0.16 12.3 0.3 2.7 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain FAM184 PF15665.5 GBG79429.1 - 0.45 10.3 7.1 0.76 9.5 7.1 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF4335 PF14233.6 GBG79429.1 - 0.53 10.2 2.4 1.1 9.1 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4335) DUF3347 PF11827.8 GBG79429.1 - 1.7 8.8 4.7 2.9 8.0 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Integrase_H2C2 PF17921.1 GBG79430.1 - 2e-15 56.6 1.2 3.7e-15 55.8 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG79430.1 - 7e-09 35.9 0.0 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Myb_DNA-bind_4 PF13837.6 GBG79430.1 - 9.4e-09 35.5 5.4 2e-08 34.5 5.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-H2C2 PF09337.10 GBG79430.1 - 3.2e-05 24.1 0.0 7.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG79431.1 - 7.3e-26 90.1 0.0 1.5e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79431.1 - 1.3e-22 80.1 0.0 2.4e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79431.1 - 1.9e-12 47.2 0.0 3.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2457 PF10446.9 GBG79431.1 - 0.17 11.0 26.1 0.34 10.0 26.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.25 GBG79433.1 - 2e-64 217.5 0.0 2.6e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79433.1 - 1.6e-32 112.8 0.0 2.4e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GBG79433.1 - 2.2e-06 27.2 0.1 5e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG79433.1 - 0.00047 20.2 0.0 0.0033 17.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_6 PF13405.6 GBG79433.1 - 0.0019 18.0 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 GBG79433.1 - 0.0035 16.8 0.1 0.0077 15.7 0.1 1.6 1 0 0 1 1 1 1 EF hand Kinase-like PF14531.6 GBG79433.1 - 0.0044 16.4 0.2 0.018 14.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like EF-hand_7 PF13499.6 GBG79433.1 - 0.011 16.1 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 GBG79433.1 - 0.1 12.1 0.5 0.22 11.1 0.5 1.5 1 0 0 1 1 1 0 EF hand gag-asp_proteas PF13975.6 GBG79434.1 - 6.3e-07 29.9 0.0 1.6e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79434.1 - 1.4e-05 25.6 0.0 3.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79434.1 - 0.00082 19.2 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG79434.1 - 0.0032 17.8 0.0 0.0077 16.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG79434.1 - 0.0034 17.6 0.1 0.018 15.3 0.1 2.0 1 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG79434.1 - 0.025 14.4 1.0 0.039 13.8 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG79434.1 - 0.12 12.5 0.6 0.22 11.7 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG79436.1 - 0.066 13.6 0.1 0.099 13.0 0.1 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DGOK PF05035.12 GBG79436.1 - 0.076 11.9 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase gag-asp_proteas PF13975.6 GBG79437.1 - 5.6e-05 23.6 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79437.1 - 0.00026 21.6 0.0 0.00061 20.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG79437.1 - 0.0011 19.2 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG79437.1 - 0.002 17.9 0.3 0.0057 16.5 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Strep_SA_rep PF06696.11 GBG79437.1 - 0.12 12.4 0.2 0.12 12.4 0.2 1.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF659 PF04937.15 GBG79438.1 - 6.7e-21 74.7 0.0 1.1e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SDA1 PF05285.12 GBG79438.1 - 7.5 5.9 22.8 0.096 12.1 10.4 2.5 2 0 0 2 2 2 0 SDA1 zf-CCHC PF00098.23 GBG79439.1 - 0.016 15.3 0.7 0.034 14.2 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Cupin_8 PF13621.6 GBG79440.1 - 2e-22 80.2 0.1 2e-20 73.6 0.0 3.0 2 1 1 3 3 3 1 Cupin-like domain JmjC PF02373.22 GBG79440.1 - 2.3e-11 44.1 0.3 2e-05 25.0 0.1 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase F-box-like PF12937.7 GBG79440.1 - 8.4e-05 22.4 0.1 0.00026 20.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG79440.1 - 0.003 17.4 0.0 0.0074 16.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain HAD_SAK_2 PF18143.1 GBG79440.1 - 0.014 15.8 0.2 0.7 10.2 0.1 2.5 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins Cupin_4 PF08007.12 GBG79440.1 - 0.076 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_1 PF00190.22 GBG79440.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 Cupin CT47 PF15623.6 GBG79440.1 - 0.63 9.8 7.3 1.2 9.0 6.8 1.6 2 0 0 2 2 2 0 Cancer/testis gene family 47 Aldedh PF00171.22 GBG79441.1 - 9.7e-119 396.9 0.1 9.7e-119 396.9 0.1 2.8 3 0 0 3 3 3 1 Aldehyde dehydrogenase family Phage_lysozyme PF00959.19 GBG79441.1 - 8.6e-05 23.0 0.2 0.11 12.9 0.0 2.8 2 0 0 2 2 2 2 Phage lysozyme Es2 PF09751.9 GBG79441.1 - 2 8.1 20.7 3.3 7.4 20.7 1.3 1 0 0 1 1 1 0 Nuclear protein Es2 RT_RNaseH PF17917.1 GBG79442.1 - 8e-23 80.7 0.0 2.4e-22 79.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79442.1 - 2.2e-19 69.3 0.0 5.3e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase IL1_propep PF02394.16 GBG79443.1 - 0.061 14.3 2.0 0.064 14.2 0.3 1.9 2 0 0 2 2 2 0 Interleukin-1 propeptide Aldedh PF00171.22 GBG79444.1 - 0.0068 15.0 0.0 0.0087 14.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RVT_1 PF00078.27 GBG79446.1 - 1.7e-33 116.1 0.0 2.7e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG79446.1 - 4.2e-07 29.8 0.0 9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79446.1 - 3.6e-06 27.5 0.0 8.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79446.1 - 0.00012 22.6 0.1 0.00039 20.9 0.1 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG79446.1 - 0.0019 18.0 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 GBG79446.1 - 0.095 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG79446.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG79447.1 - 7.3e-66 218.5 0.0 5.6e-34 116.2 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79447.1 - 1.6e-58 195.5 0.0 9.2e-30 103.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79447.1 - 3e-28 98.9 0.0 5.1e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79447.1 - 9e-11 41.7 0.0 2.8e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG79447.1 - 0.0007 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG79447.1 - 0.00097 18.9 0.1 0.0017 18.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79447.1 - 0.004 17.7 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79447.1 - 0.023 15.3 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DivIC PF04977.15 GBG79447.1 - 0.72 9.7 5.1 2.8 7.8 5.1 2.0 1 0 0 1 1 1 0 Septum formation initiator PriA_3primeBD PF17764.1 GBG79448.1 - 0.027 14.3 0.5 0.64 10.0 0.1 2.5 1 1 0 2 2 2 0 3′ DNA-binding domain (3′BD) DUF4226 PF10774.9 GBG79448.1 - 0.051 13.9 1.1 0.051 13.9 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) DUF3240 PF11582.8 GBG79448.1 - 0.15 12.2 3.0 2.7 8.2 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3240) Baculo_PEP_C PF04513.12 GBG79448.1 - 0.51 10.4 6.9 0.99 9.4 1.5 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FPP PF05911.11 GBG79448.1 - 0.68 8.1 32.3 1.2 7.2 20.2 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF3114 PF11311.8 GBG79448.1 - 2.2 7.7 10.7 4.6 6.7 5.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3114) NPV_P10 PF05531.12 GBG79448.1 - 2.7 8.5 7.7 7 7.2 0.2 3.0 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Vfa1 PF08432.10 GBG79448.1 - 9.7 6.5 12.6 19 5.5 12.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FUSC PF04632.12 GBG79448.1 - 10 4.5 8.4 12 4.2 8.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sulfate_transp PF00916.20 GBG79449.1 - 4.7e-105 351.5 13.8 5e-59 200.0 0.7 2.0 1 1 1 2 2 2 2 Sulfate permease family COX2-transmemb PF09125.10 GBG79449.1 - 5.8 6.8 6.8 17 5.3 1.2 2.8 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane Sulfate_transp PF00916.20 GBG79450.1 - 2.4e-106 355.7 11.5 2.8e-106 355.5 11.5 1.0 1 0 0 1 1 1 1 Sulfate permease family PSS PF03034.15 GBG79450.1 - 0.066 13.0 0.3 0.31 10.7 0.3 2.0 1 1 1 2 2 2 0 Phosphatidyl serine synthase Sulfate_transp PF00916.20 GBG79451.1 - 2.4e-106 355.7 11.5 2.8e-106 355.5 11.5 1.0 1 0 0 1 1 1 1 Sulfate permease family PSS PF03034.15 GBG79451.1 - 0.066 13.0 0.3 0.31 10.7 0.3 2.0 1 1 1 2 2 2 0 Phosphatidyl serine synthase FAM176 PF14851.6 GBG79452.1 - 0.0014 18.4 1.4 0.0014 18.4 1.4 2.8 2 1 1 3 3 3 1 FAM176 family SDA1 PF05285.12 GBG79452.1 - 0.0021 17.6 15.2 0.0028 17.1 15.2 1.4 1 0 0 1 1 1 1 SDA1 DUF2615 PF11027.8 GBG79452.1 - 0.054 13.6 1.5 0.12 12.5 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Tmemb_9 PF05434.11 GBG79452.1 - 0.079 12.9 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 TMEM9 NOA36 PF06524.12 GBG79452.1 - 0.45 9.8 38.8 0.71 9.1 10.4 2.3 2 0 0 2 2 2 0 NOA36 protein RVT_1 PF00078.27 GBG79453.1 - 4.5e-29 101.6 0.0 7.1e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79453.1 - 3.4e-23 81.6 0.0 1.1e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79453.1 - 4.3e-22 78.4 0.0 8.2e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG79453.1 - 6.3e-08 32.5 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79453.1 - 1.3e-07 32.2 0.0 2.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79453.1 - 3.2e-06 27.6 0.0 7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG79453.1 - 0.0018 18.1 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease KH_1 PF00013.29 GBG79454.1 - 4.2e-06 26.5 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 KH domain RT_RNaseH_2 PF17919.1 GBG79455.1 - 8.3e-27 93.2 0.0 1.5e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79455.1 - 1.7e-24 86.1 0.0 2.6e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79455.1 - 3.9e-09 36.4 0.0 5.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG79455.1 - 0.047 13.6 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) DUF659 PF04937.15 GBG79456.1 - 4.5e-15 55.8 0.0 6.4e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG79456.1 - 1.9e-07 30.8 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1192 PF06698.11 GBG79456.1 - 0.035 14.2 1.4 0.13 12.3 1.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF659 PF04937.15 GBG79457.1 - 8.5e-37 126.3 1.9 1.4e-36 125.7 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG79458.1 - 0.015 15.1 2.7 0.065 13.1 2.7 2.2 1 0 0 1 1 1 0 AT hook motif XG_FTase PF03254.13 GBG79459.1 - 1.8e-16 59.8 2.3 2.7e-08 32.9 0.9 3.1 2 1 0 2 2 2 2 Xyloglucan fucosyltransferase O-FucT PF10250.9 GBG79459.1 - 0.015 15.0 1.4 0.035 13.8 1.4 1.6 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 GBG79459.1 - 0.022 14.0 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 11 RT_RNaseH_2 PF17919.1 GBG79461.1 - 8e-23 80.4 0.0 1.8e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79461.1 - 1e-17 64.4 0.1 2.2e-17 63.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79461.1 - 2e-13 50.5 0.0 3.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG79461.1 - 9.1e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79461.1 - 0.00015 22.4 0.0 0.00033 21.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79461.1 - 0.006 17.1 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Dus PF01207.17 GBG79463.1 - 5.9e-49 166.8 0.0 8.8e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 GBG79463.1 - 5.5e-06 26.2 6.2 0.00083 19.2 0.1 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GBG79463.1 - 9.5e-05 22.1 7.0 0.00096 18.9 0.3 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger PEP_mutase PF13714.6 GBG79463.1 - 0.0041 16.6 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase oligo_HPY PF08352.12 GBG79463.1 - 0.15 12.6 1.6 2.8 8.5 0.1 2.9 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf_CCCH_4 PF18345.1 GBG79463.1 - 0.53 10.4 11.3 0.43 10.7 1.9 3.4 3 0 0 3 3 3 0 Zinc finger domain Ribophorin_I PF04597.14 GBG79464.1 - 5.1e-129 431.3 0.0 6.3e-129 431.0 0.0 1.1 1 0 0 1 1 1 1 Ribophorin I OmpH PF03938.14 GBG79464.1 - 0.043 14.2 1.9 0.14 12.5 1.9 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 GBG79464.1 - 0.066 13.4 5.1 2.6 8.2 1.3 2.9 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour IZUMO PF15005.6 GBG79464.1 - 0.17 12.4 1.1 4.4 7.8 0.2 2.2 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated HisKA_3 PF07730.13 GBG79464.1 - 0.94 10.0 6.8 0.23 12.0 1.4 2.6 2 1 1 3 3 3 0 Histidine kinase ApoLp-III PF07464.11 GBG79464.1 - 1.2 9.2 5.2 5.5 7.1 1.6 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TEX13 PF15186.6 GBG79464.1 - 1.9 8.1 6.5 0.27 10.9 1.3 2.0 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family CLZ PF16526.5 GBG79464.1 - 5 7.6 6.8 2.8 8.4 1.9 2.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2203 PF09969.9 GBG79464.1 - 6.3 7.5 6.9 13 6.5 0.3 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2207 PF09972.9 GBG79465.1 - 0.041 12.7 4.6 0.051 12.3 4.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Vps55 PF04133.14 GBG79465.1 - 0.061 13.3 4.1 0.085 12.8 4.1 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 55 AbfB PF05270.13 GBG79465.1 - 0.062 13.3 0.0 0.09 12.8 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) domain FtsX PF02687.21 GBG79465.1 - 0.11 13.0 0.1 0.11 13.0 0.1 2.7 2 1 0 2 2 2 0 FtsX-like permease family DUF3784 PF12650.7 GBG79465.1 - 0.12 12.6 7.7 5.6 7.2 5.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF4131 PF13567.6 GBG79465.1 - 0.17 11.5 2.2 0.36 10.5 1.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4191 PF13829.6 GBG79465.1 - 3.9 6.8 4.2 2.2 7.5 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) Collagen PF01391.18 GBG79466.1 - 0.11 12.2 0.3 0.11 12.2 0.3 2.2 3 0 0 3 3 3 0 Collagen triple helix repeat (20 copies) CTP_transf_3 PF02348.19 GBG79467.1 - 3.5e-16 59.8 0.1 3.3e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 Cytidylyltransferase QLQ PF08880.11 GBG79467.1 - 0.06 13.1 1.2 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 QLQ FerB PF08150.12 GBG79469.1 - 0.07 13.7 0.1 8.8 7.0 0.0 2.7 2 0 0 2 2 2 0 FerB (NUC096) domain RVT_1 PF00078.27 GBG79471.1 - 8e-36 123.6 0.1 1.3e-35 122.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG79471.1 - 2.3e-06 27.4 0.0 5.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79471.1 - 1.3e-05 25.8 0.0 2.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79471.1 - 0.0028 18.2 0.0 0.0096 16.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG79471.1 - 0.046 13.5 0.0 0.21 11.4 0.0 2.1 2 1 0 2 2 2 0 Aspartyl protease F-box-like PF12937.7 GBG79472.1 - 2.6e-07 30.4 0.0 6.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG79472.1 - 8.5e-06 25.5 0.0 5.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 GBG79472.1 - 0.00032 21.0 4.4 2.9 8.4 0.0 4.2 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG79472.1 - 0.00054 19.7 3.2 0.00079 19.1 0.2 2.7 4 0 0 4 4 4 1 Leucine rich repeat CAP_N PF01213.19 GBG79472.1 - 0.79 9.1 3.3 1.2 8.6 3.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RVT_1 PF00078.27 GBG79473.1 - 5.9e-25 88.1 0.0 9.3e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_tran PF00005.27 GBG79474.1 - 1.1e-43 149.1 0.0 1.1e-21 77.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 GBG79474.1 - 2.1e-34 119.2 26.9 2.7e-20 72.8 6.3 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 GBG79474.1 - 5.2e-09 36.3 0.0 0.0095 15.8 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GBG79474.1 - 0.00014 21.8 1.3 0.0099 15.8 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 GBG79474.1 - 0.0012 18.5 1.0 0.18 11.6 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG79474.1 - 0.0031 17.9 0.3 0.16 12.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 GBG79474.1 - 0.0079 15.6 0.0 3.4 7.0 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GBG79474.1 - 0.019 15.1 0.5 2.3 8.3 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 GBG79474.1 - 0.023 14.8 1.8 0.45 10.6 0.4 2.4 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 GBG79474.1 - 0.18 12.3 0.3 11 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 GBG79475.1 - 1.8e-51 175.0 0.0 3.4e-51 174.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79475.1 - 5.5e-29 101.2 0.0 2.2e-28 99.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG79475.1 - 0.012 14.5 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 GBG79475.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family HhH-GPD PF00730.25 GBG79476.1 - 4.9e-20 72.0 0.0 1e-19 71.0 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GBG79476.1 - 3.9e-10 39.1 0.2 3.4e-09 36.1 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GBG79476.1 - 0.00034 21.2 0.0 0.6 10.8 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_8 PF14716.6 GBG79476.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain PseudoU_synth_2 PF00849.22 GBG79478.1 - 1.5e-11 44.6 0.0 2.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 GBG79478.1 - 4.3e-11 42.4 0.0 1e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 S4 domain CCSAP PF15748.5 GBG79479.1 - 7.6 6.6 44.2 10 6.2 44.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BUD22 PF09073.10 GBG79479.1 - 8.8 5.5 73.1 13 4.9 73.1 1.3 1 0 0 1 1 1 0 BUD22 SlyX PF04102.12 GBG79480.1 - 0.1 13.2 2.3 0.97 10.1 0.0 3.2 3 0 0 3 3 3 0 SlyX DUF4407 PF14362.6 GBG79480.1 - 0.41 10.0 6.8 0.27 10.6 4.6 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF659 PF04937.15 GBG79481.1 - 1.8e-13 50.6 0.0 2.6e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Asp_protease_2 PF13650.6 GBG79483.1 - 0.00059 20.4 0.0 0.0024 18.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79483.1 - 0.0014 19.1 0.0 0.0036 17.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG79483.1 - 0.076 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Utp14 PF04615.13 GBG79485.1 - 0.069 11.7 10.1 0.069 11.7 10.1 1.0 1 0 0 1 1 1 0 Utp14 protein SpoIIIAH PF12685.7 GBG79485.1 - 0.088 12.6 4.6 0.092 12.6 4.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Presenilin PF01080.17 GBG79485.1 - 0.87 8.3 4.6 0.93 8.2 4.6 1.0 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GBG79485.1 - 2 7.7 18.1 2.7 7.3 18.1 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG79485.1 - 2.1 7.7 24.1 2.7 7.3 24.1 1.2 1 0 0 1 1 1 0 SDA1 SelK_SelG PF10961.8 GBG79485.1 - 2.3 8.9 24.3 3.1 8.5 0.6 2.2 2 0 0 2 2 2 0 Selenoprotein SelK_SelG DUF3043 PF11241.8 GBG79485.1 - 4.7 7.2 4.9 6 6.9 4.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) RRN3 PF05327.11 GBG79485.1 - 5.4 5.4 11.8 6.5 5.2 11.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 gag-asp_proteas PF13975.6 GBG79486.1 - 0.016 15.7 0.1 0.038 14.5 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease ATE_N PF04376.13 GBG79486.1 - 0.073 13.5 0.4 0.69 10.4 0.0 2.5 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus zf-CCHC PF00098.23 GBG79486.1 - 0.079 13.1 1.9 0.14 12.3 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 GBG79486.1 - 0.099 13.3 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG79486.1 - 0.2 11.4 1.7 0.26 11.0 0.3 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like FAM76 PF16046.5 GBG79488.1 - 0.11 11.8 6.0 0.18 11.2 6.0 1.1 1 0 0 1 1 1 0 FAM76 protein DDE_Tnp_4 PF13359.6 GBG79489.1 - 1.9e-27 95.8 0.0 2.8e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79489.1 - 4.1e-20 72.3 0.0 6.6e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79489.1 - 0.024 14.3 0.1 5.5 6.6 0.0 2.4 2 1 0 2 2 2 0 Transposase DDE domain RT_RNaseH PF17917.1 GBG79491.1 - 4.1e-09 36.7 0.0 7.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79491.1 - 0.0027 17.7 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG79491.1 - 1.2 7.3 7.9 1.5 7.0 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Topo_Zn_Ribbon PF08272.11 GBG79494.1 - 0.01 15.5 0.4 0.022 14.4 0.4 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVP_2 PF08284.11 GBG79494.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease GATase_4 PF13230.6 GBG79497.1 - 1.7e-10 40.2 0.1 7.2e-10 38.2 0.1 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 GBG79497.1 - 1.3e-08 35.1 0.0 3.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GBG79499.1 - 3.2e-09 37.1 0.0 6.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GBG79499.1 - 4.5e-09 35.6 0.2 2e-07 30.2 0.2 2.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Mif2_N PF15624.6 GBG79499.1 - 0.1 13.3 2.4 0.16 12.7 0.4 2.1 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Copine PF07002.16 GBG79501.1 - 5.4e-34 117.5 0.0 8.6e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Copine zf-C3HC4_3 PF13920.6 GBG79501.1 - 0.00065 19.5 9.1 0.001 18.9 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG79501.1 - 1.3 8.9 10.9 2.5 8.0 10.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG79501.1 - 1.7 8.6 9.5 3.8 7.4 9.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG79501.1 - 9.8 6.2 12.0 19 5.3 12.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Na_trans_assoc PF06512.13 GBG79502.1 - 0.035 14.4 16.6 0.067 13.5 16.5 1.6 1 1 0 1 1 1 0 Sodium ion transport-associated Cwf_Cwc_15 PF04889.12 GBG79502.1 - 0.48 10.1 25.1 0.67 9.6 25.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Serinc PF03348.15 GBG79502.1 - 0.75 8.6 1.6 1.2 8.0 1.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nop14 PF04147.12 GBG79502.1 - 1.1 7.4 31.0 1.4 7.1 31.0 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG79502.1 - 2 7.1 10.2 2.4 6.8 10.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 GBG79502.1 - 3.7 6.3 12.0 4.6 6.0 12.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.12 GBG79502.1 - 4 6.8 33.7 5.1 6.4 33.7 1.1 1 0 0 1 1 1 0 SDA1 Neur_chan_memb PF02932.16 GBG79502.1 - 5.4 7.0 5.4 7.2 6.6 5.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 GBG79502.1 - 7.3 4.8 25.1 9.4 4.4 25.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Ldl_recept_a PF00057.18 GBG79503.1 - 2.4e-16 59.7 30.3 3.7e-09 36.7 10.7 2.6 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.7 GBG79503.1 - 0.053 13.3 15.8 0.11 12.3 15.8 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like SKG6 PF08693.10 GBG79503.1 - 4.4 6.8 12.4 0.064 12.7 3.9 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DDE_Tnp_4 PF13359.6 GBG79505.1 - 3.9e-29 101.4 0.0 5.9e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79505.1 - 2.6e-14 53.3 0.0 4.3e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79505.1 - 0.036 13.7 0.1 0.094 12.3 0.0 1.7 2 0 0 2 2 2 0 Transposase DDE domain PBP1_TM PF14812.6 GBG79506.1 - 0.01 16.2 1.8 0.027 14.9 1.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myb_DNA-bind_4 PF13837.6 GBG79507.1 - 9e-12 45.2 0.8 1.8e-11 44.3 0.8 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG79507.1 - 0.0018 18.6 0.1 0.0044 17.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG79507.1 - 4.8 7.3 6.9 0.75 9.9 1.9 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain FAM180 PF15173.6 GBG79508.1 - 0.037 14.0 0.1 10 6.1 0.0 2.3 2 0 0 2 2 2 0 FAM180 family Sec62 PF03839.16 GBG79508.1 - 5.5 6.4 5.9 9 5.7 5.9 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 FKBP_C PF00254.28 GBG79509.1 - 1.7e-74 246.2 0.9 4.1e-33 113.6 0.0 3.5 3 0 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 GBG79509.1 - 2.7e-10 39.6 6.4 2.8e-05 23.7 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG79509.1 - 3.4e-08 33.0 5.6 0.00016 21.6 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_N_2 PF18023.1 GBG79509.1 - 1.3e-06 28.5 0.0 0.01 16.0 0.0 3.9 3 2 0 3 3 3 2 BDBT FKBP like N-terminal TPR_11 PF13414.6 GBG79509.1 - 4.3e-05 23.1 2.7 0.2 11.4 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 GBG79509.1 - 0.0011 19.0 4.6 0.0069 16.5 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG79509.1 - 0.0019 18.8 0.1 0.25 12.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG79509.1 - 0.0024 18.3 2.3 0.0034 17.9 0.7 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG79509.1 - 0.0053 17.0 0.5 0.16 12.3 0.3 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG79509.1 - 0.042 14.2 1.0 0.1 13.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG79509.1 - 0.045 13.9 0.1 0.091 12.9 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG79509.1 - 0.074 13.9 1.1 0.32 11.9 0.7 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG79509.1 - 0.33 11.2 5.0 1.1 9.5 0.3 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CENP-B_dimeris PF09026.10 GBG79510.1 - 0.036 14.4 4.4 0.077 13.4 4.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2722 PF10846.8 GBG79510.1 - 0.092 11.7 0.2 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FAM176 PF14851.6 GBG79510.1 - 0.17 11.5 1.9 0.28 10.8 1.9 1.3 1 0 0 1 1 1 0 FAM176 family Med4 PF10018.9 GBG79510.1 - 0.37 10.5 3.8 0.62 9.7 3.8 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 FKBP_C PF00254.28 GBG79512.1 - 3.3e-74 245.3 0.7 4.1e-33 113.6 0.0 3.5 3 0 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 GBG79512.1 - 8.2e-10 38.1 11.1 2.7e-05 23.8 0.1 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG79512.1 - 4.2e-09 35.8 4.5 0.00036 20.4 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat FKBP_N_2 PF18023.1 GBG79512.1 - 1.5e-06 28.3 0.0 0.009 16.1 0.0 3.9 3 2 0 3 3 3 2 BDBT FKBP like N-terminal TPR_8 PF13181.6 GBG79512.1 - 3.2e-06 26.9 5.5 0.0012 18.9 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG79512.1 - 4.5e-06 26.2 2.6 0.025 14.2 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 GBG79512.1 - 0.00044 20.7 2.0 0.0021 18.6 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG79512.1 - 0.0016 18.7 0.4 0.11 12.8 0.2 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG79512.1 - 0.013 16.2 0.1 4.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG79512.1 - 0.045 14.6 0.2 1.3 10.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG79512.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG79512.1 - 0.38 11.2 1.8 0.86 10.1 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG79512.1 - 0.5 11.1 1.9 40 5.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG79512.1 - 1.3 9.3 6.4 2.1 8.7 0.3 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_L7Ae PF01248.26 GBG79514.1 - 1.2e-25 89.0 0.0 1.4e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 GBG79514.1 - 0.029 14.5 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF659 PF04937.15 GBG79516.1 - 1.1e-08 35.1 0.0 2.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG79518.1 - 1.1e-13 51.3 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG79518.1 - 6.5e-09 35.5 0.2 3.2e-08 33.2 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Dimer_Tnp_hAT PF05699.14 GBG79520.1 - 3.8e-08 33.0 0.1 7.6e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG79521.1 - 8e-25 87.5 0.0 1.3e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DNA_pol_phi PF04931.13 GBG79521.1 - 0.00087 17.5 16.7 0.0013 16.9 16.7 1.2 1 0 0 1 1 1 1 DNA polymerase phi NOA36 PF06524.12 GBG79521.1 - 0.057 12.7 15.8 0.094 12.0 15.8 1.3 1 0 0 1 1 1 0 NOA36 protein Spem1 PF15670.5 GBG79521.1 - 0.23 11.0 8.3 0.51 9.9 8.3 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 Nop14 PF04147.12 GBG79521.1 - 0.39 8.9 26.9 1.9 6.6 27.2 1.7 2 0 0 2 2 2 0 Nop14-like family SAPS PF04499.15 GBG79521.1 - 0.97 8.1 7.5 1.6 7.4 7.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1168 PF06658.12 GBG79521.1 - 2.5 7.9 39.3 6.5 6.6 39.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Radial_spoke PF04712.12 GBG79521.1 - 2.7 6.8 24.2 5.2 5.9 24.2 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein eIF-3_zeta PF05091.12 GBG79521.1 - 3.5 6.5 15.6 7 5.5 15.6 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PPP4R2 PF09184.11 GBG79521.1 - 3.7 7.1 26.5 7.4 6.1 26.5 1.5 1 0 0 1 1 1 0 PPP4R2 SAGA-Tad1 PF12767.7 GBG79521.1 - 4.6 6.9 12.6 0.75 9.5 8.7 1.6 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Zip PF02535.22 GBG79521.1 - 6.3 5.9 5.8 9.4 5.3 5.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2151 PF10221.9 GBG79521.1 - 7.6 5.0 11.6 11 4.4 11.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator NPR3 PF03666.13 GBG79521.1 - 8 5.1 21.9 7.5 5.2 20.5 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Sporozoite_P67 PF05642.11 GBG79521.1 - 9.3 4.2 8.3 19 3.2 8.3 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.13 GBG79521.1 - 9.8 6.1 19.8 0.73 9.8 14.2 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 GBG79522.1 - 0.079 11.1 3.1 0.11 10.6 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG79522.1 - 0.15 10.3 11.5 0.22 9.8 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein ORC3_N PF07034.11 GBG79522.1 - 0.67 9.0 2.5 1 8.4 2.5 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus TFB6 PF17110.5 GBG79522.1 - 1.4 8.6 3.6 2.6 7.8 3.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SPATIAL PF15256.6 GBG79522.1 - 3.3 8.0 5.6 1.4 9.2 3.2 1.5 1 1 0 1 1 1 0 SPATIAL BUD22 PF09073.10 GBG79523.1 - 1e-14 54.8 80.9 2.7e-07 30.3 60.3 4.3 2 1 1 3 3 3 3 BUD22 NPR3 PF03666.13 GBG79524.1 - 1.6 7.5 3.7 3.6 6.3 3.7 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SNF2_N PF00176.23 GBG79525.1 - 3.4e-26 91.8 0.0 5.9e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HARP PF07443.13 GBG79525.1 - 1.8e-13 49.9 0.0 8.9e-05 22.1 0.0 3.8 4 0 0 4 4 4 3 HepA-related protein (HARP) Helicase_C PF00271.31 GBG79525.1 - 4.1e-12 46.4 0.0 1.3e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG79525.1 - 4.9e-05 23.4 0.0 0.00026 21.0 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit NAM-associated PF14303.6 GBG79525.1 - 0.018 15.8 1.8 0.018 15.8 1.8 2.6 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Lipase_GDSL_2 PF13472.6 GBG79525.1 - 0.071 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RMI1_C PF16099.5 GBG79526.1 - 1.3 8.9 5.1 0.55 10.1 2.1 1.8 1 1 1 2 2 2 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Rota_VP2 PF05087.12 GBG79526.1 - 2.6 6.1 3.8 3.4 5.7 3.8 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein RT_RNaseH_2 PF17919.1 GBG79527.1 - 4.8e-29 100.3 0.0 1.8e-15 56.8 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79527.1 - 1.3e-27 96.2 0.0 3.3e-27 94.8 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79527.1 - 2.1e-13 50.5 0.1 1.1e-12 48.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG79527.1 - 1.1e-11 44.7 0.1 2.8e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG79527.1 - 2.1e-10 40.5 0.3 4.3e-10 39.5 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG79527.1 - 0.036 14.3 0.0 0.095 12.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_3 PF13456.6 GBG79527.1 - 0.14 11.9 0.1 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like Integrase_H2C2 PF17921.1 GBG79529.1 - 3.2e-14 52.8 0.1 6.9e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG79529.1 - 8.6e-08 32.7 0.0 1.6e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG79529.1 - 1.4e-06 28.5 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG79529.1 - 4.4e-05 24.0 0.0 9.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79529.1 - 0.0015 18.3 0.6 0.0027 17.5 0.6 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG79529.1 - 0.01 16.1 0.0 0.029 14.7 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG79529.1 - 0.04 14.1 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger BSP_II PF05432.11 GBG79530.1 - 0.65 9.7 58.7 1.4 8.6 58.7 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF659 PF04937.15 GBG79531.1 - 3.3e-26 92.0 0.0 1.5e-25 89.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Hid1 PF12722.7 GBG79531.1 - 5.6 5.0 14.6 8.6 4.3 14.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 GBG79531.1 - 8.7 3.3 17.4 12 2.9 17.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer rve PF00665.26 GBG79532.1 - 9.2e-08 32.3 0.0 2.9e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG79532.1 - 0.00011 22.2 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG79532.1 - 0.00092 19.7 0.3 0.0047 17.5 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG79532.1 - 0.0017 18.6 0.0 0.0072 16.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG79532.1 - 0.0082 16.8 0.1 0.041 14.5 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Prothymosin PF03247.14 GBG79532.1 - 1.1 9.8 12.5 4.7 7.7 12.5 2.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family API5 PF05918.11 GBG79532.1 - 3.1 6.5 6.2 6.7 5.4 6.2 1.5 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CENP-N PF05238.13 GBG79532.1 - 3.3 6.9 6.6 3.1 7.0 5.2 1.6 2 0 0 2 2 2 0 Kinetochore protein CHL4 like FAM76 PF16046.5 GBG79533.1 - 0.017 14.5 8.6 0.022 14.1 8.6 1.1 1 0 0 1 1 1 0 FAM76 protein PspB PF06667.12 GBG79533.1 - 1.1 9.4 9.2 14 5.9 0.2 3.2 3 1 0 3 3 3 0 Phage shock protein B MRP-S26 PF14943.6 GBG79533.1 - 1.5 8.7 13.3 25 4.7 12.6 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 APG6_N PF17675.1 GBG79533.1 - 6.5 7.3 26.5 1.4 9.4 2.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Dimer_Tnp_hAT PF05699.14 GBG79534.1 - 1.4e-08 34.4 0.0 4.1e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Cytochrom_B559 PF00283.19 GBG79534.1 - 5.1 6.6 6.2 18 4.9 1.4 2.4 2 0 0 2 2 2 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits RT_RNaseH_2 PF17919.1 GBG79535.1 - 1.5e-18 66.7 0.0 3.2e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79535.1 - 2.8e-18 66.2 0.1 4.2e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79535.1 - 3.5e-10 40.1 0.0 9.3e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG79535.1 - 0.0019 17.4 0.1 0.0027 16.9 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 Ribosomal_L34 PF00468.17 GBG79536.1 - 4.7e-11 42.5 8.6 9.5e-11 41.5 8.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Sigma70_r2 PF04542.14 GBG79537.1 - 5.2e-14 51.8 0.0 1.2e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 GBG79537.1 - 6.5e-09 35.2 0.5 7.3e-08 31.8 0.1 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 GBG79537.1 - 0.037 14.1 0.1 3.2 7.9 0.0 3.1 3 0 0 3 3 3 0 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 GBG79537.1 - 0.046 13.4 0.1 0.19 11.4 0.1 2.1 1 1 0 1 1 1 0 Sigma-70, region 4 Toxin_10 PF05431.11 GBG79537.1 - 0.13 11.7 0.3 0.26 10.7 0.3 1.4 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 Lin-8 PF03353.15 GBG79537.1 - 0.71 9.4 6.5 1.1 8.8 6.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spem1 PF15670.5 GBG79537.1 - 9.9 5.7 7.3 25 4.4 0.2 2.6 3 0 0 3 3 3 0 Spermatid maturation protein 1 GLTP PF08718.11 GBG79538.1 - 4.5e-33 114.6 0.0 1.2e-32 113.2 0.0 1.8 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) rve PF00665.26 GBG79538.1 - 2.8e-05 24.3 0.3 9.5e-05 22.6 0.3 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG79538.1 - 0.006 16.8 2.2 0.029 14.6 0.1 3.1 2 0 0 2 2 2 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG79538.1 - 0.017 15.8 3.2 0.017 15.8 3.2 3.3 5 0 0 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4618 PF15397.6 GBG79538.1 - 0.05 13.0 0.2 0.13 11.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Chromo PF00385.24 GBG79538.1 - 0.062 13.2 0.0 0.22 11.5 0.0 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain BLOC1_2 PF10046.9 GBG79538.1 - 2.3 8.6 4.2 22 5.4 0.7 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 GBG79538.1 - 4.9 7.7 10.0 3.2 8.3 5.8 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region Syntaxin-18_N PF10496.9 GBG79540.1 - 1e-06 28.9 0.4 0.0018 18.5 0.0 3.0 2 1 1 3 3 3 2 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 GBG79540.1 - 0.0013 18.7 0.2 0.0029 17.6 0.2 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 GBG79540.1 - 0.0076 15.5 0.1 0.019 14.2 0.1 1.7 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain TMCO5 PF14992.6 GBG79540.1 - 0.064 12.8 4.2 0.3 10.6 4.0 1.8 1 1 1 2 2 2 0 TMCO5 family CorA PF01544.18 GBG79540.1 - 0.12 11.6 2.7 0.066 12.5 1.1 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-HIT PF04438.16 GBG79541.1 - 1.2e-10 41.0 12.5 2.1e-10 40.3 12.5 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 GBG79541.1 - 0.003 17.6 6.9 0.003 17.6 6.9 1.8 1 1 0 1 1 1 1 MYND finger zf-C2H2_4 PF13894.6 GBG79541.1 - 3.2 8.8 8.8 0.58 11.2 3.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger AAA PF00004.29 GBG79542.1 - 8.4e-43 146.0 1.0 8.4e-41 139.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 GBG79542.1 - 3.9e-06 26.9 0.0 3.9e-06 26.9 0.0 2.5 2 1 0 2 2 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 GBG79542.1 - 4.3e-06 26.4 0.9 1.2e-05 25.0 0.1 2.2 3 0 0 3 3 2 1 AAA+ lid domain AAA_2 PF07724.14 GBG79542.1 - 2.6e-05 24.4 0.0 2.6e-05 24.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GBG79542.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG79542.1 - 0.00091 19.5 0.1 0.037 14.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GBG79542.1 - 0.0012 18.9 0.0 0.004 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG79542.1 - 0.0013 19.1 2.2 0.0015 18.9 0.2 2.1 2 1 0 2 2 1 1 AAA ATPase domain Phage_Gp23 PF10669.9 GBG79542.1 - 0.007 16.7 6.0 0.019 15.3 6.0 1.7 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) TIP49 PF06068.13 GBG79542.1 - 0.013 14.7 0.1 0.04 13.1 0.1 1.8 1 0 0 1 1 1 0 TIP49 P-loop domain Ntox15 PF15604.6 GBG79542.1 - 0.032 14.3 4.8 0.25 11.5 5.3 2.1 2 0 0 2 2 2 0 Novel toxin 15 Sigma54_activat PF00158.26 GBG79542.1 - 0.063 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Alpha_GJ PF03229.13 GBG79542.1 - 0.068 13.7 0.2 0.53 10.8 0.2 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J IstB_IS21 PF01695.17 GBG79542.1 - 0.069 12.9 0.1 0.19 11.4 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein Tfb4 PF03850.14 GBG79542.1 - 0.075 12.5 0.6 0.13 11.7 0.6 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 TsaE PF02367.17 GBG79542.1 - 0.092 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE WASH-7_C PF14746.6 GBG79542.1 - 0.13 11.9 1.8 0.28 10.9 1.8 1.5 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Zeta_toxin PF06414.12 GBG79542.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 1 0 Zeta toxin OSTbeta PF15048.6 GBG79542.1 - 0.34 11.1 4.3 0.096 12.8 0.7 2.0 2 0 0 2 2 1 0 Organic solute transporter subunit beta protein NACHT PF05729.12 GBG79542.1 - 0.55 10.1 1.9 0.65 9.9 0.1 2.1 3 0 0 3 3 2 0 NACHT domain AAA_18 PF13238.6 GBG79542.1 - 0.62 10.6 0.0 0.62 10.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Connexin PF00029.19 GBG79542.1 - 6.4 6.5 5.6 0.6 9.8 1.0 1.5 2 0 0 2 2 1 0 Connexin Mito_fiss_reg PF05308.11 GBG79543.1 - 0.0089 16.1 2.5 0.0098 16.0 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial fission regulator HAUS-augmin3 PF14932.6 GBG79543.1 - 0.033 13.8 2.5 0.043 13.4 2.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 MRF_C1 PF13887.6 GBG79543.1 - 0.035 13.3 2.5 2.5 7.3 0.2 2.9 3 0 0 3 3 3 0 Myelin gene regulatory factor -C-terminal domain 1 Macoilin PF09726.9 GBG79543.1 - 0.039 12.5 7.5 0.04 12.5 7.5 1.1 1 0 0 1 1 1 0 Macoilin family T2SSF PF00482.23 GBG79543.1 - 0.075 13.0 3.2 0.09 12.7 3.2 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F WES_acyltransf PF03007.16 GBG79543.1 - 0.13 12.1 3.9 0.14 11.9 3.9 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain RT_RNaseH PF17917.1 GBG79545.1 - 7.2e-22 77.7 0.0 1.6e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79545.1 - 6.5e-20 71.0 0.0 1.5e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79545.1 - 2.4e-09 37.0 0.0 4.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_2 PF07719.17 GBG79546.1 - 1.3e-16 59.3 20.2 0.0016 18.4 0.1 10.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 GBG79546.1 - 3.4e-14 52.0 14.1 0.008 16.0 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 GBG79546.1 - 1e-11 44.6 25.7 0.74 10.8 0.1 10.5 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG79546.1 - 1.3e-10 41.6 13.9 6.7 7.3 0.0 9.1 7 1 2 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 GBG79546.1 - 4.1e-10 38.9 9.9 0.25 11.5 0.1 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG79546.1 - 1.1e-06 28.4 9.8 0.21 11.9 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG79546.1 - 2.1e-06 27.3 3.9 0.85 9.4 0.0 5.6 5 0 0 5 5 5 1 TPR repeat TPR_16 PF13432.6 GBG79546.1 - 7e-06 26.6 20.9 3.9 8.2 0.0 7.8 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG79546.1 - 3e-05 24.1 0.4 0.95 10.0 0.0 6.0 8 0 0 8 8 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG79546.1 - 6.5e-05 23.1 15.7 0.91 9.8 0.1 7.3 7 2 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GBG79546.1 - 0.00031 21.0 18.3 0.58 10.5 0.9 7.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG79546.1 - 0.13 12.5 9.3 1.8 8.8 0.4 5.0 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 GBG79546.1 - 1.6 9.1 12.3 9.2 6.7 0.5 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG79546.1 - 1.6 9.5 14.2 12 6.8 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat gag-asp_proteas PF13975.6 GBG79547.1 - 1.3e-07 32.0 0.1 3.5e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79547.1 - 2.5e-06 28.0 0.1 9e-06 26.2 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79547.1 - 9.7e-05 22.2 0.2 0.00019 21.3 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79547.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG79547.1 - 0.13 12.0 0.3 0.23 11.1 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like gag-asp_proteas PF13975.6 GBG79548.1 - 4.4e-06 27.2 0.0 9.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG79548.1 - 0.00013 21.7 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79548.1 - 0.00015 21.5 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79548.1 - 0.00022 21.8 0.1 0.00057 20.5 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease TGT PF01702.18 GBG79549.1 - 4.9e-85 285.8 0.4 9e-85 284.9 0.4 1.4 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase CHCH PF06747.13 GBG79550.1 - 0.0023 18.0 5.9 0.0052 16.9 5.9 1.6 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 GBG79550.1 - 0.0054 17.0 1.5 0.0054 17.0 1.5 2.7 3 0 0 3 3 3 1 Cytochrome c oxidase assembly protein PET191 KELK PF15796.5 GBG79550.1 - 0.01 16.3 9.6 0.01 16.3 9.6 8.0 7 2 1 8 8 8 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RVT_1 PF00078.27 GBG79551.1 - 6.7e-20 71.6 0.1 9.9e-20 71.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG79551.1 - 1.5e-08 35.1 0.0 3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79551.1 - 9.5e-08 32.6 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79551.1 - 7.7e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG79551.1 - 2.2e-06 27.5 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG79552.1 - 6e-27 93.6 0.0 1.2e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79552.1 - 2.9e-22 78.9 0.1 1.5e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79552.1 - 2.3e-14 53.5 0.1 3.8e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG79552.1 - 0.026 13.7 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 zf-CCHC PF00098.23 GBG79553.1 - 2.7e-06 27.2 2.0 4.5e-06 26.5 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG79553.1 - 0.0044 16.7 0.5 0.0075 16.0 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG79553.1 - 0.028 14.3 0.7 0.11 12.3 0.7 2.1 1 0 0 1 1 1 0 Zinc knuckle Piwi PF02171.17 GBG79554.1 - 4.6e-94 315.1 0.0 6.3e-94 314.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 GBG79554.1 - 3.6e-16 59.2 0.0 5.9e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 GBG79554.1 - 4.6e-11 43.5 0.0 1.1e-10 42.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 GBG79554.1 - 1.1e-09 37.8 0.1 2.6e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 GBG79554.1 - 1.4e-06 28.5 0.0 4.9e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 GBG79554.1 - 0.00059 20.1 0.2 0.0042 17.3 0.1 2.3 2 0 0 2 2 2 1 Mid domain of argonaute Opi1 PF08618.10 GBG79554.1 - 0.19 10.9 0.0 0.45 9.7 0.0 1.6 1 0 0 1 1 1 0 Transcription factor Opi1 zf-CCHC PF00098.23 GBG79556.1 - 1.8e-06 27.8 4.5 1.8e-06 27.8 4.5 1.9 2 0 0 2 2 2 1 Zinc knuckle TAF4 PF05236.14 GBG79556.1 - 0.0012 18.6 10.6 0.002 18.0 10.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family zf-CCHC_5 PF14787.6 GBG79556.1 - 0.19 11.4 2.1 0.49 10.2 2.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RT_RNaseH_2 PF17919.1 GBG79557.1 - 6.5e-16 58.2 0.0 1.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79557.1 - 7.9e-16 58.2 0.0 1.6e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79557.1 - 7.5e-12 45.2 0.0 1.8e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG79557.1 - 4.5e-06 26.3 0.0 8.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79557.1 - 0.0002 21.6 0.0 0.00066 19.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG79557.1 - 0.02 15.1 0.3 0.051 13.8 0.3 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG79557.1 - 0.038 14.6 0.0 0.086 13.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG79557.1 - 0.14 12.7 0.1 0.31 11.6 0.1 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Chorion_2 PF03964.15 GBG79558.1 - 0.0021 18.9 1.2 0.0021 18.9 1.2 2.2 2 0 0 2 2 2 1 Chorion family 2 YfhO PF09586.10 GBG79558.1 - 0.94 7.6 14.1 1.2 7.3 14.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3488 PF11992.8 GBG79558.1 - 6.6 5.6 7.5 9.9 5.0 6.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3488) RT_RNaseH PF17917.1 GBG79560.1 - 4.5e-31 107.2 0.0 9.2e-31 106.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79560.1 - 5.1e-29 100.2 0.0 9.9e-29 99.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG79560.1 - 7.1e-08 32.3 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG79560.1 - 1.3e-06 28.2 1.2 2.7e-06 27.2 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG79560.1 - 1.5e-05 25.4 0.0 3.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79560.1 - 0.00099 19.7 0.0 0.0054 17.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG79560.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG79560.1 - 0.026 14.4 3.3 0.055 13.3 3.3 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG79561.1 - 0.032 13.7 0.1 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG79562.1 - 0.00024 21.0 2.1 0.00051 20.0 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG79562.1 - 1.1 9.1 2.9 2 8.3 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG79563.1 - 0.029 13.9 0.1 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PI_PP_I PF18363.1 GBG79563.1 - 0.28 11.4 0.9 32 4.8 0.1 3.2 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain gag-asp_proteas PF13975.6 GBG79565.1 - 1.3e-07 32.1 0.0 3.6e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79565.1 - 2e-06 28.4 0.0 7e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79565.1 - 6.3e-06 26.0 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79565.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Phage_head_fibr PF11133.8 GBG79565.1 - 0.092 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Head fiber protein Topo_Zn_Ribbon PF08272.11 GBG79565.1 - 0.11 12.2 0.2 0.23 11.2 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG79565.1 - 0.32 11.2 1.9 0.6 10.3 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle LMWPc PF01451.21 GBG79566.1 - 6.7e-38 130.3 0.0 1.2e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Piwi PF02171.17 GBG79568.1 - 0.0024 17.2 0.0 0.0027 17.0 0.0 1.0 1 0 0 1 1 1 1 Piwi domain NOA36 PF06524.12 GBG79568.1 - 0.22 10.8 10.4 0.24 10.7 10.4 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 GBG79568.1 - 0.32 10.1 10.7 0.31 10.1 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 GBG79568.1 - 2.8 7.6 9.7 2.7 7.6 9.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PAZ PF02170.22 GBG79569.1 - 1.8e-08 34.3 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 PAZ domain Q_salvage PF10343.9 GBG79569.1 - 6.2e-07 29.3 0.0 9.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family MPS2 PF17060.5 GBG79570.1 - 0.0023 17.3 1.7 0.0046 16.3 1.7 1.4 1 0 0 1 1 1 1 Monopolar spindle protein 2 CTP_transf_like PF01467.26 GBG79570.1 - 0.024 14.8 0.5 0.055 13.7 0.5 1.6 1 0 0 1 1 1 0 Cytidylyltransferase-like G-patch PF01585.23 GBG79571.1 - 1.6e-15 56.7 3.4 5.6e-15 55.0 1.9 2.3 2 0 0 2 2 2 1 G-patch domain Borrelia_P83 PF05262.11 GBG79571.1 - 0.051 12.1 1.3 0.063 11.8 1.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Atrophin-1 PF03154.15 GBG79571.1 - 0.72 8.1 20.2 1.2 7.3 20.2 1.3 1 0 0 1 1 1 0 Atrophin-1 family eIF3_subunit PF08597.10 GBG79571.1 - 0.77 9.6 8.8 1.2 8.9 8.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit NARP1 PF12569.8 GBG79571.1 - 1.2 8.0 7.0 1.7 7.4 7.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Mitofilin PF09731.9 GBG79571.1 - 1.9 7.2 14.2 2.7 6.7 14.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein VIR_N PF15912.5 GBG79571.1 - 2 7.9 4.5 3.3 7.2 4.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF5401 PF17380.2 GBG79571.1 - 4.6 5.2 25.0 6.6 4.7 25.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Tom7 PF08038.12 GBG79572.1 - 5.3e-16 58.0 0.7 7.9e-16 57.4 0.7 1.3 1 0 0 1 1 1 1 TOM7 family Tom7 PF08038.12 GBG79573.1 - 7.3e-16 57.6 0.7 1.1e-15 57.0 0.7 1.3 1 0 0 1 1 1 1 TOM7 family Hydrolase_4 PF12146.8 GBG79574.1 - 2e-08 33.8 0.0 0.0069 15.7 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG79574.1 - 3.1e-07 31.2 0.0 9.1e-07 29.7 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG79574.1 - 9.1e-07 28.8 0.0 0.00038 20.2 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 GBG79574.1 - 1.8e-06 27.9 0.0 3.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 GBG79574.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein PGAP1 PF07819.13 GBG79574.1 - 0.059 13.1 0.0 0.29 10.8 0.0 2.0 1 1 1 2 2 2 0 PGAP1-like protein DLH PF01738.18 GBG79574.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.25 GBG79574.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) WD40 PF00400.32 GBG79575.1 - 7.1e-21 74.1 5.9 0.0016 19.2 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG79575.1 - 0.00034 20.9 0.1 22 5.4 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG79575.1 - 0.012 14.3 0.0 0.08 11.6 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.11 GBG79575.1 - 0.045 13.6 0.0 1.7 8.5 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Inhibitor_I71 PF12628.7 GBG79575.1 - 0.083 12.7 1.8 0.33 10.8 0.0 2.4 3 0 0 3 3 3 0 Falstatin, cysteine peptidase inhibitor PA26 PF04636.13 GBG79576.1 - 0.0057 15.6 8.1 0.0065 15.4 8.1 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) RE_AlwI PF09491.10 GBG79576.1 - 0.034 13.0 3.5 0.035 12.9 3.5 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF3138 PF11336.8 GBG79576.1 - 0.18 10.4 0.8 0.21 10.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SET PF00856.28 GBG79576.1 - 0.28 11.5 2.3 0.33 11.3 2.3 1.2 1 0 0 1 1 1 0 SET domain PRTP PF01366.18 GBG79576.1 - 0.72 7.8 7.0 0.84 7.6 7.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF5401 PF17380.2 GBG79576.1 - 1.2 7.1 24.6 1.4 6.9 24.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Herpes_UL25 PF01499.16 GBG79576.1 - 2 6.8 8.0 2.3 6.6 8.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF4407 PF14362.6 GBG79576.1 - 6 6.1 13.4 8 5.7 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nucleo_P87 PF07267.11 GBG79576.1 - 6.4 5.5 9.7 7.5 5.3 9.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.11 GBG79576.1 - 6.5 6.3 16.1 9.5 5.7 16.1 1.2 1 0 0 1 1 1 0 PPP4R2 TMPIT PF07851.13 GBG79576.1 - 8.6 5.5 6.0 9.6 5.3 6.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Phospholip_A2_1 PF00068.19 GBG79578.1 - 0.034 14.6 2.5 0.059 13.8 2.5 1.3 1 0 0 1 1 1 0 Phospholipase A2 RVT_1 PF00078.27 GBG79579.1 - 3.2e-36 124.9 0.0 5e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG79579.1 - 9.9e-07 28.6 0.0 2.8e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79579.1 - 1.4e-05 25.6 0.0 3.3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79579.1 - 0.00046 20.7 0.3 0.0018 18.8 0.0 2.2 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG79579.1 - 0.047 13.5 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG79579.1 - 0.074 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF3138 PF11336.8 GBG79579.1 - 0.14 10.7 4.1 0.24 10.0 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PRTP PF01366.18 GBG79579.1 - 9.4 4.1 9.7 19 3.2 9.7 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Casc1_N PF15927.5 GBG79581.1 - 0.054 13.2 10.4 0.13 12.0 10.4 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF659 PF04937.15 GBG79582.1 - 3.6e-30 104.8 0.1 6.3e-30 104.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Lipase_3 PF01764.25 GBG79582.1 - 1.5e-20 73.5 0.0 3.3e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) RT_RNaseH_2 PF17919.1 GBG79582.1 - 2.9e-16 59.3 0.0 6.9e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79582.1 - 3.8e-07 30.4 0.0 1.3e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG79582.1 - 1e-06 29.3 0.0 3.6e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79582.1 - 3.1e-06 27.0 0.0 6.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG79582.1 - 1.7e-05 24.5 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG79582.1 - 0.00087 19.8 0.0 0.0023 18.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG79582.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF1289 PF06945.13 GBG79583.1 - 0.1 12.4 1.8 0.18 11.6 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DUF659 PF04937.15 GBG79584.1 - 4.1e-10 39.7 0.0 6.8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG79585.1 - 6.5e-26 91.2 0.4 1.3e-25 90.2 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG79585.1 - 0.0016 18.6 7.9 0.004 17.4 0.1 4.1 4 0 0 4 4 4 1 Retrotransposon gag protein CLZ PF16526.5 GBG79585.1 - 0.058 13.8 5.2 0.11 12.9 0.6 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RT_RNaseH_2 PF17919.1 GBG79586.1 - 6.5e-25 87.1 0.0 1.1e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79586.1 - 1.1e-23 83.4 0.0 2.1e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79586.1 - 1.1e-20 74.1 0.0 1.9e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDH1_2_SANT_HL1 PF18375.1 GBG79586.1 - 0.11 13.2 1.1 3 8.6 0.0 2.6 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 AAA PF00004.29 GBG79589.1 - 8.7e-06 26.2 0.0 2.9e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GBG79589.1 - 0.00021 21.3 0.0 0.003 17.5 0.0 2.7 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 GBG79589.1 - 0.014 15.7 2.3 0.04 14.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 GBG79589.1 - 0.12 12.7 1.2 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DJ-1_PfpI PF01965.24 GBG79590.1 - 4e-108 358.5 0.0 9.2e-53 178.4 0.0 2.0 2 0 0 2 2 2 2 DJ-1/PfpI family ThiJ_like PF17124.5 GBG79590.1 - 1.3e-07 31.5 0.1 0.0054 16.4 0.0 3.3 2 2 1 3 3 3 2 ThiJ/PfpI family-like GATase PF00117.28 GBG79590.1 - 4.3e-06 26.6 0.0 0.089 12.6 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Catalase_C PF18011.1 GBG79590.1 - 1.2e-05 25.0 0.0 0.043 13.4 0.0 2.4 2 0 0 2 2 2 2 C-terminal domain found in long catalases GATase_3 PF07685.14 GBG79590.1 - 5.7e-05 22.8 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 GBG79590.1 - 7.2e-05 22.7 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family DUF3053 PF11254.8 GBG79590.1 - 0.024 14.2 0.0 5.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) Peptidase_C26 PF07722.13 GBG79590.1 - 0.11 12.2 0.1 20 4.8 0.0 2.8 2 1 0 2 2 2 0 Peptidase C26 CCB1 PF12046.8 GBG79591.1 - 1.2e-56 190.7 0.0 1.5e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B Hydrolase_4 PF12146.8 GBG79592.1 - 2e-58 197.5 0.4 7.8e-58 195.6 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG79592.1 - 1.4e-10 41.3 0.0 5.5e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG79592.1 - 6.7e-10 39.9 0.0 1.1e-09 39.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GBG79592.1 - 8.6e-07 28.6 4.2 0.0068 15.9 0.0 3.1 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GBG79592.1 - 4.3e-05 23.4 0.0 1.3 8.8 0.0 3.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 GBG79592.1 - 0.002 18.0 0.9 0.0051 16.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 GBG79592.1 - 0.0022 17.7 0.0 0.0022 17.7 0.0 2.3 2 1 0 2 2 1 1 Putative esterase PGAP1 PF07819.13 GBG79592.1 - 0.12 12.1 0.7 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Macoilin PF09726.9 GBG79592.1 - 0.17 10.4 27.8 0.23 10.0 27.8 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 GBG79592.1 - 0.38 9.4 14.3 0.5 9.0 14.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitofilin PF09731.9 GBG79592.1 - 0.42 9.4 33.2 0.57 9.0 33.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4551 PF15087.6 GBG79592.1 - 0.47 9.2 23.7 0.63 8.8 23.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RVT_1 PF00078.27 GBG79593.1 - 1e-35 123.3 0.0 1.9e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Heme_oxygenase PF01126.20 GBG79593.1 - 3e-12 46.8 0.1 3.3e-11 43.4 0.1 2.1 2 0 0 2 2 2 1 Heme oxygenase KH_7 PF17214.3 GBG79593.1 - 0.078 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 KH domain Na_H_Exchanger PF00999.21 GBG79594.1 - 2e-65 221.0 47.1 2.4e-65 220.8 47.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2457 PF10446.9 GBG79595.1 - 0.023 13.9 7.1 0.03 13.5 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 GBG79595.1 - 0.12 11.7 1.4 0.15 11.4 1.4 1.1 1 0 0 1 1 1 0 BUD22 Myb_DNA-binding PF00249.31 GBG79596.1 - 2e-18 66.3 0.3 8.2e-15 54.7 0.3 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG79596.1 - 2.5e-10 40.4 1.3 2.7e-08 33.9 0.5 3.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 GBG79596.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 SLIDE YL1 PF05764.13 GBG79596.1 - 2.4 8.2 13.8 0.034 14.3 4.4 2.1 2 0 0 2 2 2 0 YL1 nuclear protein RVT_1 PF00078.27 GBG79597.1 - 4e-18 65.7 0.1 1.6e-17 63.8 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79597.1 - 4.6e-15 55.5 0.0 8.9e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79597.1 - 0.0005 20.3 0.0 0.00095 19.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF223 PF02721.14 GBG79599.1 - 0.071 13.4 0.1 0.26 11.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF223 FlgM PF04316.13 GBG79599.1 - 5.6 7.4 10.4 68 3.9 0.3 3.4 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM Integrase_H2C2 PF17921.1 GBG79600.1 - 2.7e-09 37.0 0.0 7.5e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79600.1 - 2.3e-06 27.8 0.0 1.6e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain SKA1 PF07160.12 GBG79600.1 - 1.9 8.3 5.0 0.18 11.6 0.2 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 BUD22 PF09073.10 GBG79601.1 - 2.4 7.4 17.1 3.2 7.0 17.1 1.1 1 0 0 1 1 1 0 BUD22 DDE_Tnp_4 PF13359.6 GBG79602.1 - 2.3e-31 108.6 0.0 9.5e-31 106.6 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79602.1 - 1.9e-16 60.3 0.0 3.3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79602.1 - 8.3e-08 32.1 1.6 0.0014 18.3 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG79604.1 - 6.1e-12 45.8 0.6 5.4e-10 39.5 0.2 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF695 PF05117.12 GBG79604.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF695) Myb_DNA-bind_5 PF13873.6 GBG79604.1 - 0.2 11.7 0.6 0.53 10.4 0.6 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG79605.1 - 5.5e-05 23.1 2.8 0.00011 22.1 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG79605.1 - 0.013 15.3 5.1 0.021 14.6 5.1 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF2381 PF09544.10 GBG79605.1 - 6.1 6.3 14.1 1 8.9 8.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) CAF-1_p150 PF11600.8 GBG79605.1 - 8.5 6.0 37.7 2.2 7.9 22.8 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NPV_P10 PF05531.12 GBG79606.1 - 0.42 11.1 2.4 15 6.1 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DDE_Tnp_4 PF13359.6 GBG79608.1 - 1.7e-20 73.3 0.0 2.9e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79608.1 - 1.8e-07 30.9 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79608.1 - 0.044 13.4 0.0 5.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG79609.1 - 3.2e-05 24.2 1.5 4.5e-05 23.8 0.8 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG79609.1 - 0.0065 16.5 0.2 0.014 15.5 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG79609.1 - 0.041 14.1 0.2 0.074 13.2 0.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Apo-CII PF05355.11 GBG79609.1 - 0.074 13.2 0.2 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein C-II Dimer_Tnp_hAT PF05699.14 GBG79610.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DEAD PF00270.29 GBG79613.1 - 1.2e-22 80.6 0.0 3.6e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG79613.1 - 5.8e-20 71.7 0.0 1.2e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GBG79613.1 - 0.0022 17.3 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SDA1 PF05285.12 GBG79613.1 - 0.91 8.9 12.6 1.3 8.4 12.6 1.2 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG79614.1 - 3.4e-31 108.5 0.0 7.2e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79614.1 - 8.1e-11 41.8 0.0 2.2e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG79614.1 - 6.8e-10 38.9 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79614.1 - 1.2e-07 32.3 0.0 2.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79614.1 - 1.1e-05 25.9 0.0 3.2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG79614.1 - 0.0058 16.9 2.5 0.012 15.8 0.3 2.8 2 1 1 3 3 3 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG79614.1 - 0.015 15.6 0.2 0.063 13.6 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG79614.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease APG17 PF04108.12 GBG79614.1 - 0.05 12.7 0.3 0.24 10.5 0.0 2.0 2 0 0 2 2 2 0 Autophagy protein Apg17 RVP PF00077.20 GBG79614.1 - 0.15 12.4 0.0 0.44 10.9 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease CTP_transf_like PF01467.26 GBG79615.1 - 1.6e-31 109.4 0.0 3.3e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like ABC2_membrane PF01061.24 GBG79617.1 - 7.3e-45 153.0 18.5 9.3e-45 152.6 18.5 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GBG79617.1 - 3.9e-22 79.2 0.0 6.1e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG79617.1 - 2.5e-07 30.1 15.1 4.9e-07 29.2 15.1 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG79617.1 - 5.9e-05 23.0 0.1 0.11 12.2 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GBG79617.1 - 0.00057 19.5 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GBG79617.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 GBG79617.1 - 0.0031 17.0 0.0 0.027 13.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GBG79617.1 - 0.036 14.4 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 GBG79617.1 - 0.055 14.0 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GBG79617.1 - 0.061 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 GBG79617.1 - 0.13 12.5 0.2 0.32 11.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GBG79617.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PhoH PF02562.16 GBG79617.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 GBG79617.1 - 0.19 12.1 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 GBG79617.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PHO4 PF01384.20 GBG79617.1 - 0.62 9.0 6.3 0.97 8.4 6.3 1.3 1 0 0 1 1 1 0 Phosphate transporter family ABC2_membrane_2 PF12679.7 GBG79617.1 - 1.2 8.4 9.7 0.16 11.3 2.4 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Mito_fiss_reg PF05308.11 GBG79621.1 - 0.024 14.7 1.2 0.024 14.7 1.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Folate_rec PF03024.14 GBG79623.1 - 0.0049 16.8 0.1 0.0049 16.8 0.1 2.1 2 0 0 2 2 2 1 Folate receptor family NPC1_N PF16414.5 GBG79623.1 - 0.044 13.3 0.0 0.044 13.3 0.0 2.0 2 0 0 2 2 2 0 Niemann-Pick C1 N terminus ZapB PF06005.12 GBG79624.1 - 0.04 14.4 8.7 4.8 7.7 0.5 3.6 2 2 1 3 3 3 0 Cell division protein ZapB DUF2383 PF09537.10 GBG79624.1 - 0.08 13.3 1.7 10 6.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) PikAIV_N PF18605.1 GBG79624.1 - 0.31 10.6 4.8 0.23 11.1 0.6 2.9 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DivIC PF04977.15 GBG79624.1 - 0.42 10.4 10.1 2 8.3 0.2 3.6 2 2 1 3 3 3 0 Septum formation initiator G_path_suppress PF15991.5 GBG79624.1 - 0.43 10.7 4.8 4.6 7.3 2.2 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor Cep57_CLD_2 PF14197.6 GBG79624.1 - 1.1 9.4 8.9 11 6.2 3.8 3.1 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Cnn_1N PF07989.11 GBG79624.1 - 2.6 8.3 9.2 0.72 10.0 3.1 2.7 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 SlyX PF04102.12 GBG79624.1 - 2.9 8.6 10.6 64 4.3 0.1 4.4 3 2 2 5 5 5 0 SlyX PTCB-BRCT PF12738.7 GBG79625.1 - 1.6e-21 76.0 0.6 6.5e-20 70.9 0.1 3.2 3 0 0 3 3 3 1 twin BRCT domain BRCT PF00533.26 GBG79625.1 - 3.5e-20 72.2 0.0 1.3e-07 31.8 0.1 3.6 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PHD PF00628.29 GBG79625.1 - 1.8e-09 37.3 4.4 1.8e-09 37.3 4.4 1.8 2 0 0 2 2 2 1 PHD-finger BRCT_2 PF16589.5 GBG79625.1 - 1.3e-05 25.5 0.0 1.9 9.0 0.0 4.2 3 1 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 GBG79625.1 - 0.0022 17.8 0.0 0.024 14.5 0.0 2.4 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain RT_RNaseH_2 PF17919.1 GBG79627.1 - 2.7e-33 114.0 0.1 7.5e-33 112.5 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79627.1 - 4.1e-29 101.0 0.2 8.3e-29 100.0 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79627.1 - 1.5e-25 90.1 0.0 2.6e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhoLip_ATPase_N PF16209.5 GBG79627.1 - 2.3e-20 72.0 1.5 5.4e-20 70.9 1.5 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Integrase_H2C2 PF17921.1 GBG79627.1 - 1.3e-15 57.2 0.1 2.7e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79627.1 - 1.7e-14 54.0 0.0 8e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain PhoLip_ATPase_C PF16212.5 GBG79627.1 - 3e-13 50.1 0.2 6.8e-13 48.9 0.2 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 GBG79627.1 - 7.7e-11 41.9 0.0 3.6e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GBG79627.1 - 8.3e-09 36.0 0.3 0.0021 18.4 0.1 4.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase gag-asp_proteas PF13975.6 GBG79627.1 - 1.7e-05 25.3 0.0 6.2e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Virul_fac_BrkB PF03631.15 GBG79627.1 - 0.00039 20.1 0.4 0.04 13.5 1.0 2.4 2 0 0 2 2 2 1 Virulence factor BrkB E1-E2_ATPase PF00122.20 GBG79627.1 - 0.0008 19.0 0.0 0.0053 16.3 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase RVP_2 PF08284.11 GBG79627.1 - 0.0022 17.8 0.0 0.0065 16.2 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Hydrolase_3 PF08282.12 GBG79627.1 - 0.13 12.0 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4357 PF14267.6 GBG79627.1 - 0.73 9.8 2.9 1.9 8.5 2.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) RT_RNaseH_2 PF17919.1 GBG79628.1 - 7.5e-18 64.4 0.0 1.6e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79628.1 - 1.2e-08 35.2 0.0 2.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79628.1 - 4.3e-07 29.7 0.1 6.3e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG79628.1 - 0.51 9.7 18.9 0.71 9.2 18.9 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG79628.1 - 0.76 9.0 22.1 1 8.6 22.1 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG79628.1 - 1.1 7.4 17.2 1.6 6.9 17.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GBG79628.1 - 1.2 7.5 20.3 1.5 7.1 20.3 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG79628.1 - 1.8 6.7 20.9 2.5 6.2 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG79628.1 - 5.5 5.7 8.0 8 5.1 8.0 1.1 1 0 0 1 1 1 0 Presenilin zf-C3HC4_2 PF13923.6 GBG79629.1 - 1.4e-09 37.6 5.6 1.4e-09 37.6 5.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG79629.1 - 1.5e-09 38.0 4.4 1.5e-09 38.0 4.4 2.9 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 GBG79629.1 - 1.4e-08 34.5 3.4 1.4e-08 34.5 3.4 3.2 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG79629.1 - 1.6e-08 34.3 4.4 1.6e-08 34.3 4.4 2.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG79629.1 - 3.1e-08 33.4 2.4 3.1e-08 33.4 2.4 3.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG79629.1 - 3.1e-07 30.3 3.7 3.1e-07 30.3 3.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GBG79629.1 - 2e-05 24.7 1.5 2e-05 24.7 1.5 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GBG79629.1 - 0.00015 21.6 5.7 0.00015 21.6 5.7 3.4 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GBG79629.1 - 0.00028 21.0 5.6 0.00028 21.0 5.6 2.4 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.5 GBG79629.1 - 0.0031 17.9 6.3 0.0031 17.9 6.3 2.2 1 1 1 2 2 2 1 TRAF-like zinc-finger zf-ANAPC11 PF12861.7 GBG79629.1 - 0.0032 17.5 1.4 0.0032 17.5 1.4 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GBG79629.1 - 0.013 15.2 5.5 0.013 15.2 5.5 2.3 2 1 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 GBG79629.1 - 0.028 14.2 3.9 0.028 14.2 3.9 2.5 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_6 PF14835.6 GBG79629.1 - 0.51 10.2 10.4 0.086 12.7 1.8 2.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Elf1 PF05129.13 GBG79629.1 - 3.6 7.7 7.9 2.8 8.0 1.2 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like RT_RNaseH_2 PF17919.1 GBG79630.1 - 8.6e-32 109.2 0.0 1.9e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79630.1 - 3.8e-31 107.5 0.0 7.8e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79630.1 - 9.7e-20 70.4 0.2 2.1e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG79630.1 - 4.2e-13 49.3 0.1 8.6e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79630.1 - 3.2e-05 24.1 0.0 9e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79630.1 - 5.4e-05 23.3 0.1 0.00016 21.8 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG79630.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RNase_HII PF01351.18 GBG79631.1 - 2e-29 102.9 0.5 3.6e-26 92.2 0.0 2.0 1 1 1 2 2 2 2 Ribonuclease HII Methyltransf_24 PF13578.6 GBG79632.1 - 9.9e-09 36.2 0.1 3.7e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain RVT_1 PF00078.27 GBG79634.1 - 1e-26 93.8 0.0 1.7e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79634.1 - 1.1e-21 77.0 0.1 3.3e-21 75.6 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79634.1 - 6.6e-13 48.6 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79634.1 - 9.9e-13 48.3 0.0 3.3e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG79634.1 - 1.2e-12 47.7 1.4 2.3e-12 46.8 0.1 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG79634.1 - 1.2e-10 41.1 0.0 2.9e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG79634.1 - 6.7e-05 23.0 0.1 0.00014 22.0 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG79634.1 - 0.059 13.1 0.1 0.2 11.5 0.1 1.9 1 0 0 1 1 1 0 Integrase core domain Tic110 PF16940.5 GBG79636.1 - 7.5e-237 787.4 14.3 1.4e-232 773.4 5.0 3.0 2 1 1 3 3 3 2 Chloroplast envelope transporter ENT PF03735.14 GBG79636.1 - 0.001 19.1 0.2 0.01 15.9 0.0 2.8 2 1 1 3 3 3 1 ENT domain MccV PF17508.2 GBG79636.1 - 0.021 15.3 2.3 0.031 14.8 0.9 2.1 2 0 0 2 2 2 0 Microcin V bacteriocin T2SSK PF03934.13 GBG79636.1 - 0.14 11.5 4.8 2.8 7.3 0.2 3.5 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein K Annexin PF00191.20 GBG79638.1 - 7.3e-55 182.9 0.3 2.1e-19 69.3 0.0 4.2 4 0 0 4 4 4 4 Annexin SAM_Exu PF18609.1 GBG79638.1 - 0.086 12.9 0.0 0.35 11.0 0.0 2.0 1 0 0 1 1 1 0 Exuperantia SAM-like domain IL22 PF14565.6 GBG79639.1 - 0.14 12.4 1.6 2.6 8.3 0.3 2.5 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Tup_N PF08581.10 GBG79639.1 - 0.27 11.6 9.4 0.11 12.8 1.2 3.9 3 2 0 3 3 3 0 Tup N-terminal bZIP_1 PF00170.21 GBG79639.1 - 3.7 7.7 20.2 2.7 8.1 0.1 4.0 3 1 1 4 4 4 0 bZIP transcription factor LMBR1 PF04791.16 GBG79639.1 - 4.9 5.9 4.3 5.2 5.9 4.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein RVT_1 PF00078.27 GBG79640.1 - 1.4e-09 37.8 0.0 2.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG79640.1 - 1.6e-06 28.6 0.1 7.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG79640.1 - 7.5e-06 25.9 0.0 1.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG79640.1 - 6.1e-05 23.6 0.0 0.00021 21.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH PF17917.1 GBG79640.1 - 0.00025 21.3 0.0 0.00051 20.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG79640.1 - 0.01 16.1 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG79640.1 - 0.12 12.2 0.5 0.22 11.3 0.5 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG79640.1 - 0.37 10.9 1.7 0.96 9.6 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG79641.1 - 1.8e-28 98.5 0.0 3.4e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79641.1 - 6.3e-25 87.5 0.0 1.3e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79641.1 - 7.1e-14 51.8 0.1 1.2e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3381 PF11861.8 GBG79641.1 - 0.019 14.8 10.9 0.029 14.2 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Nop53 PF07767.11 GBG79641.1 - 0.35 10.2 14.8 0.46 9.8 14.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PBP1_TM PF14812.6 GBG79641.1 - 4.4 7.7 9.4 8.2 6.9 9.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_polI_A34 PF08208.11 GBG79641.1 - 7.3 6.6 19.8 10 6.1 19.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Annexin PF00191.20 GBG79642.1 - 1.4e-53 178.8 0.0 8.3e-16 57.8 0.0 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 GBG79642.1 - 0.067 13.1 0.0 0.94 9.4 0.0 2.5 2 1 1 3 3 3 0 Myb DNA-binding like Imm30 PF15565.6 GBG79642.1 - 0.14 12.3 0.0 0.46 10.6 0.0 1.9 1 0 0 1 1 1 0 Immunity protein 30 Annexin PF00191.20 GBG79644.1 - 3.5e-51 171.2 2.4 5.6e-17 61.6 0.0 4.2 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 GBG79644.1 - 0.00073 19.4 0.0 0.012 15.5 0.0 2.7 3 1 1 4 4 4 1 Myb DNA-binding like Annexin PF00191.20 GBG79645.1 - 1.4e-42 143.6 5.8 9.3e-18 64.1 0.2 4.1 4 0 0 4 4 4 4 Annexin YlbE PF14003.6 GBG79645.1 - 0.02 15.3 0.0 0.57 10.7 0.0 2.8 3 0 0 3 3 3 0 YlbE-like protein Spt5_N PF11942.8 GBG79645.1 - 0.067 14.2 1.6 4.6 8.3 0.0 2.8 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF3574 PF12098.8 GBG79645.1 - 0.18 11.6 0.2 38 4.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3574) Annexin PF00191.20 GBG79646.1 - 4.7e-60 199.6 2.4 5.3e-21 74.5 0.0 4.1 4 0 0 4 4 4 4 Annexin Peptidase_S28 PF05577.12 GBG79646.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Annexin PF00191.20 GBG79647.1 - 1.7e-43 146.5 5.1 1.3e-13 50.8 0.0 4.2 4 0 0 4 4 4 4 Annexin RVT_1 PF00078.27 GBG79648.1 - 7.8e-31 107.3 0.0 1.3e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79648.1 - 1.5e-15 57.0 0.3 5.3e-15 55.3 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG79648.1 - 1.6e-12 47.1 0.0 3.6e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG79648.1 - 7.2e-11 42.3 0.0 2e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79648.1 - 0.00066 19.8 0.1 0.0018 18.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG79649.1 - 1.7e-31 109.4 0.0 3.3e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79649.1 - 7.6e-11 41.9 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79649.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Ribosomal_L34 PF00468.17 GBG79649.1 - 0.18 11.8 0.0 5.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L34 Annexin PF00191.20 GBG79651.1 - 1.1e-43 147.1 1.1 4.2e-16 58.8 0.1 4.2 4 0 0 4 4 4 4 Annexin Brix PF04427.18 GBG79652.1 - 1e-19 71.4 0.2 3.1e-17 63.3 0.2 2.2 1 1 0 1 1 1 1 Brix domain gag-asp_proteas PF13975.6 GBG79653.1 - 9.2e-07 29.4 0.1 2.8e-06 27.8 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79653.1 - 7.2e-06 26.6 0.1 2.5e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79653.1 - 8.7e-05 22.3 0.1 0.00016 21.4 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79653.1 - 0.011 15.5 0.0 0.064 13.0 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG79653.1 - 0.11 12.2 0.2 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Ribosomal_S6 PF01250.17 GBG79653.1 - 0.12 12.6 0.1 8.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S6 BUD22 PF09073.10 GBG79654.1 - 0.15 11.4 24.1 0.18 11.1 24.1 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG79654.1 - 0.39 10.1 23.2 0.46 9.9 23.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG79654.1 - 0.47 8.6 24.5 0.57 8.3 24.5 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG79654.1 - 0.7 8.1 17.6 0.87 7.8 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 GBG79654.1 - 0.97 8.6 3.3 0.98 8.6 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 GBG79654.1 - 1.1 8.7 18.4 1.3 8.4 18.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 GBG79654.1 - 2.6 6.7 9.9 3.2 6.4 9.9 1.1 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 GBG79654.1 - 3 6.3 23.4 4.4 5.8 23.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.7 GBG79654.1 - 8.7 4.3 7.5 9.2 4.3 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_60s PF00428.19 GBG79655.1 - 7 7.3 20.1 0.29 11.8 6.1 4.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Aph-1 PF06105.12 GBG79656.1 - 8.4e-12 45.0 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Aph-1 protein Integrase_H2C2 PF17921.1 GBG79657.1 - 4.4e-14 52.3 0.5 4.4e-14 52.3 0.5 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG79657.1 - 3.4e-13 49.8 0.0 1.1e-12 48.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG79657.1 - 0.1 12.8 0.4 0.27 11.5 0.4 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG79658.1 - 0.0017 18.6 0.1 0.0047 17.2 0.0 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG79659.1 - 7.7e-09 36.0 0.1 1.6e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79659.1 - 2e-07 31.5 0.1 4.5e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG79659.1 - 0.00061 20.0 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG79659.1 - 0.0031 17.3 0.1 0.0051 16.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG79659.1 - 0.057 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG79659.1 - 0.09 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase SQAPI PF16845.5 GBG79660.1 - 2.8e-16 59.6 0.7 1e-15 57.8 0.6 1.9 2 0 0 2 2 2 1 Aspartic acid proteinase inhibitor Cystatin PF00031.21 GBG79660.1 - 1.4e-13 50.9 0.0 9.2e-12 45.1 0.1 2.2 2 0 0 2 2 2 2 Cystatin domain Branch PF02485.21 GBG79661.1 - 3.4e-58 197.1 0.3 4.3e-58 196.7 0.3 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF659 PF04937.15 GBG79662.1 - 0.00025 20.9 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Branch PF02485.21 GBG79664.1 - 6e-61 206.1 0.0 8.1e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme LCM PF04072.14 GBG79665.1 - 3e-28 99.1 0.0 8e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase F_bP_aldolase PF01116.20 GBG79667.1 - 4.3e-61 206.8 0.1 5.2e-61 206.6 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II F_bP_aldolase PF01116.20 GBG79668.1 - 7.6e-22 78.1 0.1 1.3e-21 77.3 0.1 1.3 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NBD_C PF17042.5 GBG79668.1 - 1.7e-16 61.2 0.7 1.7e-16 61.2 0.7 2.6 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain DnaJ PF00226.31 GBG79668.1 - 0.00014 21.9 0.1 0.00028 20.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain SBD_N PF07005.11 GBG79669.1 - 2.2e-47 161.7 0.0 2.2e-47 161.7 0.0 2.0 2 0 0 2 2 2 1 Sugar-binding N-terminal domain RT_RNaseH PF17917.1 GBG79669.1 - 3.5e-30 104.4 0.2 1.3e-29 102.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79669.1 - 8.1e-30 102.8 0.0 2.9e-29 101.1 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79669.1 - 5.5e-05 22.8 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4392 PF14336.6 GBG79669.1 - 0.0052 16.3 0.0 0.0052 16.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4392) RVP_2 PF08284.11 GBG79669.1 - 0.095 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease SSP160 PF06933.11 GBG79669.1 - 3 5.9 10.5 4.8 5.3 10.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NAD_binding_2 PF03446.15 GBG79670.1 - 1.3e-35 122.9 2.5 1.8e-35 122.4 2.5 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GBG79670.1 - 3.4e-14 53.1 1.2 3.4e-14 53.1 1.2 2.0 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 GBG79670.1 - 4.9e-08 32.5 0.0 6.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GBG79670.1 - 6.3e-06 26.7 0.1 1.4e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 GBG79670.1 - 2.1e-05 24.5 0.6 4e-05 23.6 0.6 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 GBG79670.1 - 0.0071 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_C PF03720.15 GBG79670.1 - 0.018 15.4 0.0 0.072 13.5 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.14 GBG79670.1 - 0.099 12.2 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Erg28 PF03694.13 GBG79672.1 - 3.4e-25 88.6 5.0 4.6e-25 88.2 5.0 1.2 1 0 0 1 1 1 1 Erg28 like protein DUF5493 PF17597.2 GBG79672.1 - 0.03 14.6 1.4 0.83 9.9 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5493) UPF0242 PF06785.11 GBG79672.1 - 3.5 7.7 4.5 0.64 10.1 1.3 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RVT_1 PF00078.27 GBG79673.1 - 8.5e-14 51.6 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4296 PF14129.6 GBG79673.1 - 0.054 14.1 0.1 0.12 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) UTP15_C PF09384.10 GBG79673.1 - 0.13 11.9 1.5 0.18 11.4 0.5 1.7 1 1 0 1 1 1 0 UTP15 C terminal Vir_act_alpha_C PF10400.9 GBG79673.1 - 0.18 12.5 2.0 0.65 10.7 2.0 2.0 1 0 0 1 1 1 0 Virulence activator alpha C-term DUF4140 PF13600.6 GBG79673.1 - 2.1 8.8 9.2 21 5.6 1.8 4.1 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Snapin_Pallidin PF14712.6 GBG79673.1 - 3.3 8.2 10.1 0.87 10.1 0.1 2.9 3 0 0 3 3 3 0 Snapin/Pallidin DUF4806 PF16064.5 GBG79673.1 - 7.9 6.9 6.0 20 5.6 0.4 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4806) HSP70 PF00012.20 GBG79675.1 - 3.5e-141 471.4 0.0 2e-140 468.8 0.0 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG79675.1 - 3e-13 49.3 6.5 4.4e-06 25.7 0.1 3.1 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 GBG79675.1 - 3.6e-05 24.1 0.9 0.033 14.6 0.0 2.9 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 GBG79675.1 - 0.06 13.1 0.3 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF3670 PF12419.8 GBG79675.1 - 0.35 10.7 1.9 1 9.2 0.0 2.3 2 0 0 2 2 2 0 SNF2 Helicase protein Raco_middle PF17651.1 GBG79675.1 - 0.72 9.5 0.0 0.72 9.5 0.0 2.1 3 0 0 3 3 3 0 RACo middle region NdhO PF11910.8 GBG79676.1 - 5e-24 84.3 0.0 7.2e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 Cyanobacterial and plant NDH-1 subunit O Myb_DNA-bind_4 PF13837.6 GBG79679.1 - 2.5e-07 31.0 6.5 9.2e-07 29.2 1.3 2.9 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG79679.1 - 0.0059 16.9 0.6 0.023 15.0 0.6 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like UPF0184 PF03670.13 GBG79679.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Myb_DNA-bind_5 PF13873.6 GBG79679.1 - 0.12 12.5 1.7 0.45 10.6 1.7 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ADH_N PF08240.12 GBG79680.1 - 1.9e-28 98.5 1.2 4e-28 97.5 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GBG79680.1 - 4e-23 81.8 2.3 2.5e-21 76.0 2.3 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GBG79680.1 - 1.8e-07 30.9 1.0 0.0081 15.7 0.0 2.7 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GBG79680.1 - 2.8e-05 25.2 0.0 5.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GBG79680.1 - 0.00092 18.6 0.3 0.0015 17.8 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AMP-binding PF00501.28 GBG79680.1 - 0.0026 16.4 0.8 0.004 15.8 0.8 1.2 1 0 0 1 1 1 1 AMP-binding enzyme 2-Hacid_dh_C PF02826.19 GBG79680.1 - 0.031 13.6 0.1 0.069 12.5 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Chloroa_b-bind PF00504.21 GBG79680.1 - 0.032 14.8 0.7 0.084 13.4 0.7 1.7 1 1 0 1 1 1 0 Chlorophyll A-B binding protein Sacchrp_dh_NADP PF03435.18 GBG79680.1 - 0.12 12.7 2.8 4.6 7.5 0.3 2.4 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 GBG79680.1 - 0.15 11.3 2.5 0.28 10.4 2.4 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GBG79680.1 - 0.76 9.6 5.3 1.9 8.3 4.9 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RPN2_C PF18004.1 GBG79680.1 - 1.6 8.6 8.0 2.5 8.0 8.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RT_RNaseH_2 PF17919.1 GBG79681.1 - 6.3e-26 90.3 0.0 1.1e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79681.1 - 4.5e-24 84.7 0.0 9e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79681.1 - 3.3e-16 59.5 0.0 6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG79681.1 - 1.2e-11 44.3 0.0 1.2e-11 44.3 0.0 2.5 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 GBG79681.1 - 0.00022 21.7 0.1 0.00044 20.8 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG79681.1 - 0.00027 20.7 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79681.1 - 0.00059 20.4 0.0 0.0013 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79681.1 - 0.0055 16.5 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DDHD PF02862.17 GBG79681.1 - 0.12 12.5 2.3 0.25 11.5 2.3 1.6 1 0 0 1 1 1 0 DDHD domain GREB1 PF15782.5 GBG79681.1 - 2.7 5.0 11.6 3.8 4.5 11.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Borrelia_P83 PF05262.11 GBG79681.1 - 7.4 4.9 19.6 10 4.5 19.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RicinB_lectin_2 PF14200.6 GBG79682.1 - 5.7e-12 46.2 0.0 0.013 16.2 0.0 3.7 2 1 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like betaPIX_CC PF16523.5 GBG79683.1 - 0.03 14.2 3.3 0.03 14.2 3.3 2.8 2 1 1 3 3 3 0 betaPIX coiled coil WASH_WAHD PF11945.8 GBG79683.1 - 0.13 11.7 8.6 0.51 9.8 0.9 2.1 2 0 0 2 2 2 0 WAHD domain of WASH complex DUF5401 PF17380.2 GBG79683.1 - 1.5 6.8 28.3 1.9 6.4 28.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Folliculin PF11704.8 GBG79683.1 - 2.6 7.9 8.8 0.24 11.2 3.3 1.8 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport RicinB_lectin_2 PF14200.6 GBG79685.1 - 2.2e-10 41.1 0.0 0.029 15.1 0.0 3.4 3 0 0 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Retrotrans_gag PF03732.17 GBG79687.1 - 0.00047 20.4 5.0 0.0061 16.8 0.0 3.6 3 1 0 3 3 3 1 Retrotransposon gag protein DUF3006 PF11213.8 GBG79687.1 - 0.085 13.1 1.6 0.23 11.7 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) SNAPc19 PF15497.6 GBG79687.1 - 0.54 10.8 4.6 1.9 9.0 0.0 2.8 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF4407 PF14362.6 GBG79687.1 - 0.65 9.3 15.5 3.6 6.8 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GIT_CC PF16559.5 GBG79687.1 - 1.4 8.8 8.8 2.4 8.1 0.1 3.4 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor CLZ PF16526.5 GBG79687.1 - 1.8 9.0 10.5 0.14 12.5 0.6 3.6 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 GBG79687.1 - 6 6.9 8.4 11 6.0 3.7 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 GBG79687.1 - 7.2 7.1 17.7 0.5 10.8 0.9 3.7 3 1 0 3 3 3 0 Cell division protein ZapB RT_RNaseH_2 PF17919.1 GBG79688.1 - 2e-25 88.7 0.0 4.6e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79688.1 - 7.1e-25 87.8 0.0 1.1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79688.1 - 1.2e-23 83.4 0.0 2.5e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79688.1 - 1.2e-15 57.3 0.5 3.3e-15 55.9 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79688.1 - 5.7e-09 36.2 0.0 1.6e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG79688.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG79690.1 - 3.9e-22 78.5 0.0 6.9e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79690.1 - 6.1e-21 74.3 0.0 1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79690.1 - 5.1e-10 39.2 0.0 9.9e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG79690.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH PF17917.1 GBG79691.1 - 4e-07 30.3 0.0 9.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79691.1 - 9.3e-07 28.8 0.1 1.9e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG79691.1 - 1.5e-06 28.0 1.2 1.5e-06 28.0 1.2 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG79691.1 - 0.4 10.5 8.2 0.03 14.1 3.3 1.7 2 0 0 2 2 2 0 Zinc knuckle Peptidase_C78 PF07910.13 GBG79692.1 - 4e-43 147.4 0.2 5.4e-41 140.4 0.0 2.6 3 0 0 3 3 3 2 Peptidase family C78 ZZ PF00569.17 GBG79692.1 - 2.5e-07 30.4 0.1 8.8e-07 28.6 0.1 2.0 1 0 0 1 1 1 1 Zinc finger, ZZ type Peptidase_C54 PF03416.19 GBG79692.1 - 0.076 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C54 UIM PF02809.20 GBG79692.1 - 0.11 12.5 1.4 0.3 11.1 1.4 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Methyltransf_31 PF13847.6 GBG79692.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C78 PF07910.13 GBG79693.1 - 2.7e-43 147.9 0.1 4.5e-41 140.7 0.0 2.7 3 0 0 3 3 3 2 Peptidase family C78 ZZ PF00569.17 GBG79693.1 - 2.8e-07 30.2 0.1 7.7e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type Peptidase_C54 PF03416.19 GBG79693.1 - 0.067 12.6 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C54 UIM PF02809.20 GBG79693.1 - 0.097 12.6 1.4 0.27 11.3 1.4 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Methyltransf_31 PF13847.6 GBG79693.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 GBG79694.1 - 4.7e-75 252.4 0.0 5.3e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79694.1 - 2.5e-31 108.9 0.0 3e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GBG79694.1 - 7.7e-05 21.8 0.2 0.00012 21.1 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GBG79694.1 - 0.00042 19.7 0.1 0.17 11.2 0.0 2.3 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 GBG79694.1 - 0.014 14.7 0.2 0.028 13.8 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG79694.1 - 0.037 14.0 0.1 0.051 13.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GBG79694.1 - 0.07 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 GBG79694.1 - 0.096 12.3 0.2 1 8.9 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF647 PF04884.14 GBG79695.1 - 1.2e-91 306.6 1.8 1.6e-91 306.3 1.8 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Reticulon PF02453.17 GBG79695.1 - 0.048 13.6 0.2 0.088 12.8 0.2 1.5 1 0 0 1 1 1 0 Reticulon DUF647 PF04884.14 GBG79696.1 - 7e-92 307.4 1.8 8.5e-92 307.1 1.8 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Reticulon PF02453.17 GBG79696.1 - 0.033 14.2 0.2 0.062 13.3 0.2 1.5 1 0 0 1 1 1 0 Reticulon TMEM65 PF10507.9 GBG79696.1 - 0.23 11.4 2.7 11 6.1 0.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 65 Mem_trans PF03547.18 GBG79697.1 - 4.5e-48 163.6 0.3 4e-47 160.5 0.3 2.0 1 1 0 1 1 1 1 Membrane transport protein Mem_trans PF03547.18 GBG79698.1 - 6.2e-37 126.9 0.0 1.7e-36 125.4 0.0 1.6 1 1 0 1 1 1 1 Membrane transport protein DUF382 PF04037.13 GBG79699.1 - 1.2e-58 196.8 1.2 1.2e-58 196.8 1.2 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF382) PSP PF04046.16 GBG79699.1 - 1.6e-21 75.9 4.2 3.3e-21 74.9 4.2 1.5 1 0 0 1 1 1 1 PSP Caldesmon PF02029.15 GBG79699.1 - 8.8 5.0 51.3 0.13 11.0 24.3 2.2 2 0 0 2 2 2 0 Caldesmon DDE_Tnp_4 PF13359.6 GBG79701.1 - 3.7e-25 88.4 0.0 6e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79701.1 - 7.5e-14 51.8 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79701.1 - 0.037 13.7 0.2 0.74 9.4 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG79701.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Sporozoite_P67 PF05642.11 GBG79702.1 - 5.9 4.8 7.1 8.3 4.4 7.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RVT_1 PF00078.27 GBG79703.1 - 1.4e-28 99.9 0.0 2.2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG79703.1 - 0.059 14.0 0.0 0.15 12.7 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG79704.1 - 2.5e-29 101.3 0.0 5.8e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79704.1 - 2e-25 89.1 0.0 5.2e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79704.1 - 4.6e-17 62.3 0.0 7.5e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG79704.1 - 9e-06 25.5 2.9 2.1e-05 24.3 2.9 1.7 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG79704.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG79704.1 - 0.00085 19.8 0.1 0.0021 18.6 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79704.1 - 0.0021 18.7 0.0 0.0057 17.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79704.1 - 0.0051 16.6 0.1 0.0085 15.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG79704.1 - 0.04 13.7 3.5 0.077 12.8 3.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Na_trans_assoc PF06512.13 GBG79705.1 - 0.27 11.5 13.4 0.38 11.0 13.4 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated RNA_pol_Rpc4 PF05132.14 GBG79705.1 - 0.82 10.1 4.2 1.3 9.4 4.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 GBG79705.1 - 2 6.5 26.9 2.9 6.0 26.9 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG79705.1 - 3.3 6.4 8.0 4.1 6.1 8.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RVT_1 PF00078.27 GBG79707.1 - 2.6e-12 46.7 0.0 3.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4746 PF15928.5 GBG79707.1 - 3.2 7.1 13.2 5.5 6.3 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Phage_HK97_TLTM PF06120.11 GBG79708.1 - 0.0022 17.3 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Tail length tape measure protein MscS_porin PF12795.7 GBG79708.1 - 0.0053 16.3 2.2 0.0072 15.9 2.2 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 GBG79708.1 - 0.0082 16.2 2.2 0.015 15.3 2.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 GBG79708.1 - 0.017 14.5 2.3 0.033 13.5 2.1 1.6 1 1 0 1 1 1 0 Tropomyosin Taxilin PF09728.9 GBG79708.1 - 0.032 13.4 0.2 0.047 12.9 0.2 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein ZapB PF06005.12 GBG79708.1 - 0.083 13.3 1.4 0.19 12.2 1.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB TolA_bind_tri PF16331.5 GBG79708.1 - 0.1 12.7 3.4 7.1 6.8 0.3 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation FUSC PF04632.12 GBG79708.1 - 0.11 11.0 1.6 0.12 10.8 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 GBG79708.1 - 0.14 12.7 1.5 0.2 12.2 1.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_Maf PF03131.17 GBG79708.1 - 0.16 12.5 3.0 2.8 8.5 0.1 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor H-kinase_dim PF02895.14 GBG79708.1 - 0.19 12.1 0.3 0.19 12.1 0.3 1.8 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain 3-PAP PF12578.8 GBG79708.1 - 0.22 11.2 0.8 18 5.1 0.2 2.4 2 0 0 2 2 2 0 Myotubularin-associated protein HAP1_N PF04849.13 GBG79708.1 - 0.51 9.5 4.5 0.59 9.3 0.5 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region PSK_trans_fac PF07704.11 GBG79708.1 - 1.4 9.8 5.8 1.1 10.1 3.4 2.1 2 1 0 2 2 2 0 Rv0623-like transcription factor DDE_Tnp_4 PF13359.6 GBG79709.1 - 7.4e-34 116.7 0.0 1.1e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79709.1 - 3.3e-14 53.0 0.0 6.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79709.1 - 0.00017 21.3 0.3 0.0029 17.3 0.3 2.5 1 1 0 1 1 1 1 Transposase DDE domain F-box-like PF12937.7 GBG79712.1 - 6.7e-08 32.3 0.3 2.8e-07 30.3 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG79712.1 - 3.6e-07 29.9 0.5 3.6e-07 29.9 0.5 2.6 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 GBG79712.1 - 0.0049 16.4 0.4 0.0049 16.4 0.4 1.8 2 0 0 2 2 2 1 F-box LRR_1 PF00560.33 GBG79712.1 - 0.04 14.5 5.8 4.9 8.1 0.1 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 GBG79712.1 - 0.37 11.0 2.7 5.9 7.2 0.9 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 GBG79712.1 - 2.6 8.6 10.7 10 6.7 0.8 5.0 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) RVT_1 PF00078.27 GBG79714.1 - 6.6e-31 107.5 0.0 1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79714.1 - 1.3e-19 70.0 0.0 2.6e-15 56.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79714.1 - 1.5e-16 60.2 0.9 7.4e-16 58.0 0.0 2.7 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG79714.1 - 1.7e-10 41.1 0.1 5.4e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG79714.1 - 1.2e-08 35.1 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG79714.1 - 2.2e-05 24.6 0.0 6.5e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG79715.1 - 0.00088 19.9 0.3 0.0092 16.6 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79715.1 - 0.0028 18.2 1.0 0.034 14.7 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease CENP-N PF05238.13 GBG79715.1 - 5.9 6.1 6.2 0.97 8.7 2.1 1.6 2 0 0 2 2 2 0 Kinetochore protein CHL4 like Myb_DNA-bind_4 PF13837.6 GBG79716.1 - 1.8e-10 41.1 5.3 3.5e-10 40.1 5.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG79716.1 - 0.0026 17.9 0.4 0.015 15.5 0.2 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG79716.1 - 0.01 16.2 2.2 0.01 16.2 2.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Nop14 PF04147.12 GBG79717.1 - 0.38 8.9 17.7 0.43 8.7 17.7 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG79717.1 - 0.63 9.4 19.0 0.78 9.1 19.0 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG79717.1 - 0.67 8.5 20.6 0.91 8.0 20.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4746 PF15928.5 GBG79717.1 - 0.75 9.2 8.3 1 8.7 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop53 PF07767.11 GBG79717.1 - 1.4 8.3 16.1 2 7.7 16.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Lin-8 PF03353.15 GBG79717.1 - 2.6 7.5 7.9 3.3 7.2 7.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 GBG79717.1 - 2.8 7.2 22.0 4.1 6.7 22.0 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 GBG79717.1 - 7 5.1 7.9 8.9 4.7 7.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RVT_1 PF00078.27 GBG79720.1 - 4.3e-26 91.8 0.1 8e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG79720.1 - 0.068 13.8 0.0 0.29 11.8 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG79720.1 - 0.073 13.3 2.2 0.081 13.2 0.2 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein TTSSLRR PF12468.8 GBG79722.1 - 0.04 14.2 0.1 0.093 13.0 0.1 1.5 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein DUF659 PF04937.15 GBG79723.1 - 1.7e-23 83.1 0.0 2.5e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Lenti_VIF_2 PF07401.12 GBG79723.1 - 0.035 13.5 0.1 0.074 12.4 0.1 1.5 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein RT_RNaseH_2 PF17919.1 GBG79724.1 - 2.1e-30 104.7 0.0 4.5e-15 55.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79724.1 - 7.1e-29 100.2 0.0 1.9e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79724.1 - 1.2e-26 93.6 0.0 2.2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79725.1 - 9e-25 86.6 0.0 3.2e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79725.1 - 1.1e-24 87.2 0.0 2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79725.1 - 3.6e-22 78.6 0.0 1e-21 77.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79725.1 - 4.2e-19 68.4 0.2 1.1e-18 67.0 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG79725.1 - 0.012 15.5 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG79725.1 - 0.065 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Plasmodium_Vir PF05795.11 GBG79727.1 - 5.6 6.3 6.6 11 5.4 6.6 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mito_carr PF00153.27 GBG79729.1 - 7.6e-37 125.1 0.0 6.6e-15 54.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GBG79729.1 - 3.9e-10 40.0 0.3 2.7e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG79729.1 - 8.7e-07 28.1 0.0 0.00015 21.1 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 GBG79729.1 - 3.9e-06 26.3 0.0 0.0011 18.7 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 GBG79729.1 - 0.00077 18.9 0.3 0.0026 17.2 0.1 2.0 2 0 0 2 2 2 1 EF hand DUF2666 PF10869.8 GBG79729.1 - 0.0043 17.3 0.1 0.72 10.1 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2666) EF-hand_8 PF13833.6 GBG79729.1 - 0.017 14.9 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair rve PF00665.26 GBG79730.1 - 2.3e-15 56.8 0.0 4.8e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG79730.1 - 4.6e-15 55.5 0.2 1e-14 54.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG79730.1 - 0.00064 20.2 0.1 0.0023 18.5 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79730.1 - 0.023 15.3 0.5 0.067 13.8 0.1 2.0 2 0 0 2 2 2 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG79730.1 - 0.078 12.7 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Integrase_H2C2 PF17921.1 GBG79731.1 - 5.2e-35 119.3 1.8 1.1e-18 67.1 0.1 3.2 3 0 0 3 3 3 2 Integrase zinc binding domain rve PF00665.26 GBG79731.1 - 2.8e-11 43.7 0.0 4.7e-06 26.8 0.1 2.6 2 0 0 2 2 2 2 Integrase core domain EF-hand_7 PF13499.6 GBG79731.1 - 2.9e-06 27.6 0.6 0.0014 19.0 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair zf-H2C2 PF09337.10 GBG79731.1 - 1e-05 25.6 0.0 0.02 15.1 0.0 2.6 2 0 0 2 2 2 2 H2C2 zinc finger EF-hand_1 PF00036.32 GBG79731.1 - 0.00029 20.2 0.1 0.0038 16.7 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 GBG79731.1 - 0.0088 15.9 0.0 0.072 13.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 GBG79731.1 - 0.18 11.4 0.2 1.6 8.3 0.0 2.7 2 0 0 2 2 2 0 EF hand Plavaka PF18759.1 GBG79732.1 - 2.2e-08 33.7 3.7 1.6e-07 30.9 0.1 2.5 1 1 1 2 2 2 2 Plavaka transposase Dehydrin PF00257.19 GBG79732.1 - 0.016 15.7 4.2 0.041 14.4 4.2 1.6 1 0 0 1 1 1 0 Dehydrin CDC27 PF09507.10 GBG79733.1 - 0.044 13.2 25.1 0.088 12.2 25.1 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sporozoite_P67 PF05642.11 GBG79733.1 - 0.056 11.5 6.4 0.075 11.1 6.4 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen eIF-3c_N PF05470.12 GBG79733.1 - 0.057 11.7 6.0 0.06 11.7 6.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 GBG79733.1 - 0.076 11.1 17.4 0.11 10.5 17.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi I-EGF_1 PF18372.1 GBG79733.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 Zip PF02535.22 GBG79733.1 - 0.4 9.9 2.8 0.45 9.7 2.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 GBG79733.1 - 0.44 9.3 18.8 0.57 8.9 18.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GBG79733.1 - 1.3 7.7 16.5 1.9 7.2 16.5 1.3 1 0 0 1 1 1 0 Presenilin Spem1 PF15670.5 GBG79733.1 - 2.4 7.7 12.8 3.3 7.2 12.8 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF2151 PF10221.9 GBG79733.1 - 3.1 6.3 13.3 3.9 6.0 13.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF1168 PF06658.12 GBG79733.1 - 3.6 7.4 41.6 9.4 6.1 41.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) NOA36 PF06524.12 GBG79733.1 - 7.1 5.9 18.1 13 4.9 18.1 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG79734.1 - 1.4 6.9 13.7 0.016 13.3 5.9 1.6 2 0 0 2 2 2 0 DNA polymerase phi Mito_carr PF00153.27 GBG79735.1 - 3.9e-36 122.9 0.0 4.8e-15 55.2 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GBG79735.1 - 1.3e-09 38.4 0.5 0.0001 22.6 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG79735.1 - 3.5e-05 23.0 0.0 0.0031 16.9 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 GBG79735.1 - 4.1e-05 23.2 0.0 0.0074 16.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 GBG79735.1 - 0.01 15.3 0.2 0.033 13.7 0.1 2.0 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 GBG79735.1 - 0.12 12.3 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair DUF2666 PF10869.8 GBG79735.1 - 0.12 12.6 0.1 17 5.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Trypan_PARP PF05887.11 GBG79735.1 - 0.65 10.0 7.2 1.7 8.6 7.2 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Chromo PF00385.24 GBG79736.1 - 4.8e-12 45.6 0.0 7.3e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2156 PF09924.9 GBG79736.1 - 0.094 11.7 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) TLV_coat PF00429.19 GBG79737.1 - 0.014 14.1 1.8 0.021 13.5 1.8 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) DUF1682 PF07946.14 GBG79737.1 - 5.4 6.1 8.8 11 5.1 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Mito_carr PF00153.27 GBG79738.1 - 3.5e-38 129.4 0.0 1.2e-15 57.2 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 GBG79741.1 - 3.6e-33 113.4 0.0 2e-14 53.2 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GBG79741.1 - 6.3e-08 33.0 0.2 0.00028 21.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG79741.1 - 0.00026 20.3 0.0 0.0023 17.4 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 GBG79741.1 - 0.00071 19.3 0.0 0.011 15.6 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 GBG79741.1 - 0.0079 15.7 0.1 0.018 14.5 0.1 1.7 1 0 0 1 1 1 1 EF hand RT_RNaseH_2 PF17919.1 GBG79742.1 - 1.9e-28 98.5 0.0 9.9e-28 96.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79742.1 - 7.5e-26 90.5 0.1 3.1e-25 88.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79742.1 - 2.6e-12 46.8 0.2 5.8e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG79742.1 - 0.11 12.1 11.8 0.43 10.1 0.0 2.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2950 PF11453.8 GBG79742.1 - 0.61 9.2 8.4 1 8.5 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) PA26 PF04636.13 GBG79742.1 - 2.4 7.0 10.7 3.7 6.4 10.7 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3629 PF12302.8 GBG79742.1 - 9.7 5.6 10.0 18 4.6 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DUF659 PF04937.15 GBG79743.1 - 6.9e-29 100.7 0.1 1e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SGP PF17228.2 GBG79745.1 - 0.04 14.8 2.8 0.09 13.6 2.8 1.6 1 0 0 1 1 1 0 Sulphur globule protein Mpv17_PMP22 PF04117.12 GBG79746.1 - 1.4e-18 66.8 0.8 2.8e-18 65.9 0.8 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family RT_RNaseH_2 PF17919.1 GBG79747.1 - 7.1e-28 96.6 0.0 1.9e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79747.1 - 2e-27 95.5 0.0 5.1e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79747.1 - 1.9e-18 66.3 0.9 4.5e-18 65.1 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79747.1 - 8.7e-18 64.6 0.0 3.2e-17 62.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79747.1 - 0.0048 17.1 0.1 0.013 15.7 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG79747.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3987 PF13148.6 GBG79747.1 - 1.5 7.7 8.4 28 3.6 9.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Presenilin PF01080.17 GBG79747.1 - 7.7 5.2 8.9 13 4.4 8.9 1.2 1 0 0 1 1 1 0 Presenilin ACP_syn_III_C PF08541.10 GBG79748.1 - 7.9e-36 122.1 0.1 2.5e-35 120.5 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 GBG79748.1 - 5.6e-31 106.2 1.2 5.6e-31 106.2 1.2 4.1 5 0 0 5 5 5 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 GBG79748.1 - 0.00024 20.6 0.0 0.00024 20.6 0.0 2.4 4 0 0 4 4 4 1 Thiolase, N-terminal domain Chal_sti_synt_C PF02797.15 GBG79748.1 - 0.00089 19.3 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain UDPG_MGDP_dh_N PF03721.14 GBG79748.1 - 0.23 11.0 0.2 1.5 8.4 0.0 2.1 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ZapB PF06005.12 GBG79749.1 - 0.0073 16.7 0.0 0.0073 16.7 0.0 3.7 3 2 0 3 3 3 1 Cell division protein ZapB FANCM-MHF_bd PF16783.5 GBG79749.1 - 0.5 10.5 5.5 0.11 12.5 1.3 2.1 2 0 0 2 2 2 0 FANCM to MHF binding domain TMF_DNA_bd PF12329.8 GBG79749.1 - 0.58 10.2 11.5 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4746 PF15928.5 GBG79749.1 - 0.72 9.2 8.9 1 8.7 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FAM76 PF16046.5 GBG79749.1 - 1.4 8.2 9.2 2.3 7.5 9.2 1.3 1 0 0 1 1 1 0 FAM76 protein NPV_P10 PF05531.12 GBG79749.1 - 1.6 9.2 5.9 6.5 7.3 1.2 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Presenilin PF01080.17 GBG79749.1 - 6.2 5.5 8.4 8.1 5.1 8.4 1.4 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG79750.1 - 8.9e-34 116.9 0.0 2.2e-33 115.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79750.1 - 6.2e-29 100.0 0.0 1.5e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79750.1 - 1.1e-28 99.6 0.0 2.1e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79750.1 - 5.5e-19 68.0 0.5 1.1e-18 67.1 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79750.1 - 1.7e-16 60.5 0.0 3.5e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79750.1 - 2.4e-05 24.5 0.1 5.5e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF3458_C PF17432.2 GBG79751.1 - 1.6e-122 408.9 1.1 2.9e-122 408.0 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 GBG79751.1 - 7.9e-57 192.3 0.3 2.4e-42 145.0 0.1 2.4 1 1 1 2 2 2 2 Peptidase family M1 domain DUF3458 PF11940.8 GBG79751.1 - 5.1e-28 97.4 0.0 1.7e-27 95.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold RVT_1 PF00078.27 GBG79751.1 - 1.7e-25 89.9 0.1 3.1e-25 89.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79751.1 - 5.8e-14 52.3 0.1 1.8e-13 50.7 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_M1_N PF17900.1 GBG79751.1 - 1.9e-13 51.0 0.0 6.1e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain RT_RNaseH_2 PF17919.1 GBG79751.1 - 1e-05 25.5 0.0 3.2e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SlyX PF04102.12 GBG79751.1 - 0.0055 17.3 3.0 0.42 11.3 0.1 3.5 3 0 0 3 3 2 1 SlyX Peptidase_M61 PF05299.12 GBG79751.1 - 0.014 15.8 0.4 0.077 13.4 0.2 2.5 2 1 0 2 2 2 0 M61 glycyl aminopeptidase APG6_N PF17675.1 GBG79751.1 - 0.015 15.8 0.0 0.042 14.4 0.0 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region Asp_Arg_Hydrox PF05118.15 GBG79751.1 - 0.054 13.3 1.1 0.12 12.2 0.2 2.0 2 0 0 2 2 2 0 Aspartyl/Asparaginyl beta-hydroxylase FlxA PF14282.6 GBG79751.1 - 0.06 13.3 0.2 0.06 13.3 0.2 2.5 3 0 0 3 3 3 0 FlxA-like protein DUF4795 PF16043.5 GBG79751.1 - 0.16 11.5 0.4 0.37 10.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DivIC PF04977.15 GBG79751.1 - 0.64 9.8 2.2 6 6.7 0.2 2.8 2 0 0 2 2 2 0 Septum formation initiator Retrotrans_gag PF03732.17 GBG79751.1 - 0.69 10.2 3.4 4.2 7.7 0.1 3.5 3 0 0 3 3 3 0 Retrotransposon gag protein DUF4140 PF13600.6 GBG79751.1 - 1.3 9.5 6.4 1.2e+02 3.1 0.0 4.9 5 0 0 5 5 5 0 N-terminal domain of unknown function (DUF4140) Peptidase_M1 PF01433.20 GBG79752.1 - 1.1e-34 119.9 0.3 1.4e-34 119.5 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 GBG79752.1 - 6.9e-12 45.7 0.0 2.4e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold DDE_Tnp_4 PF13359.6 GBG79753.1 - 1.4e-33 115.8 0.1 1.1e-32 112.9 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79753.1 - 3.2e-14 53.0 0.0 6.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79753.1 - 5.1e-07 29.6 1.1 0.0057 16.3 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain RhlB PF12300.8 GBG79753.1 - 0.034 14.3 6.4 0.069 13.3 6.4 1.5 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB zf-RING_6 PF14835.6 GBG79753.1 - 0.26 11.2 1.6 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FERM_f0 PF16511.5 GBG79754.1 - 0.48 10.8 9.1 19 5.6 0.4 3.7 1 1 2 3 3 3 0 N-terminal or F0 domain of Talin-head FERM DUF846 PF05832.12 GBG79756.1 - 2.1e-48 163.9 9.8 2.5e-48 163.7 9.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.6 GBG79756.1 - 0.0012 19.1 3.2 0.44 10.9 0.4 2.1 2 0 0 2 2 2 2 YwiC-like protein DUF2232 PF09991.9 GBG79756.1 - 0.18 11.0 10.2 0.12 11.5 1.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF4191 PF13829.6 GBG79756.1 - 0.93 8.8 7.3 0.085 12.2 1.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF4227 PF14004.6 GBG79756.1 - 4.3 7.4 5.8 0.89 9.6 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4227) RT_RNaseH PF17917.1 GBG79757.1 - 1.1e-18 67.4 0.0 2.8e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79757.1 - 5.1e-17 61.8 0.0 1.3e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79757.1 - 4e-07 29.8 0.0 7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79757.1 - 0.00042 20.5 0.0 0.0009 19.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG79757.1 - 0.017 15.7 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Peptidase_C14 PF00656.22 GBG79759.1 - 2e-27 96.8 0.0 3.4e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Nif11 PF07862.11 GBG79759.1 - 0.043 14.1 1.5 8.8 6.7 0.0 4.0 5 1 0 5 5 5 0 Nif11 domain COX4 PF02936.14 GBG79759.1 - 0.06 13.4 0.0 46 4.0 0.0 3.3 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Plus-3 PF03126.18 GBG79760.1 - 3e-27 95.3 0.3 1.3e-26 93.2 0.1 2.1 2 0 0 2 2 2 1 Plus-3 domain Roc PF08477.13 GBG79760.1 - 0.097 12.9 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase OAD_gamma PF04277.13 GBG79760.1 - 0.99 10.0 6.4 2.5 8.7 6.4 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S66 PF02016.15 GBG79761.1 - 4.8e-28 97.7 0.0 7.2e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 GBG79761.1 - 8.3e-25 87.7 0.0 1.3e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain RT_RNaseH PF17917.1 GBG79762.1 - 1.2e-29 102.7 0.1 2.8e-29 101.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79762.1 - 1e-28 99.3 0.0 1.9e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79762.1 - 1e-05 25.2 0.3 2e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HU-CCDC81_bac_2 PF18175.1 GBG79762.1 - 0.059 13.3 0.0 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 CutA1 PF03091.15 GBG79762.1 - 0.076 12.9 0.1 0.076 12.9 0.1 2.5 3 0 0 3 3 3 0 CutA1 divalent ion tolerance protein Phage_GPO PF05929.11 GBG79762.1 - 0.13 11.8 4.0 0.22 11.1 0.1 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase LEA_1 PF03760.15 GBG79762.1 - 0.15 12.7 6.7 0.46 11.2 6.7 1.8 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 RT_RNaseH PF17917.1 GBG79763.1 - 4.1e-12 46.3 0.1 1.1e-11 44.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG79763.1 - 3.4e-08 33.7 0.1 1.4e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG79763.1 - 1.4e-06 28.1 0.0 3.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79763.1 - 1.2e-05 25.8 0.0 2.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Tudor-knot PF11717.8 GBG79763.1 - 4.8e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RT_RNaseH_2 PF17919.1 GBG79763.1 - 9.5e-05 22.4 0.0 0.00027 20.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG79763.1 - 0.00044 20.8 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG79763.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Nif11 PF07862.11 GBG79763.1 - 0.029 14.7 0.0 3.8 7.9 0.0 2.7 2 0 0 2 2 2 0 Nif11 domain Chromo PF00385.24 GBG79763.1 - 0.037 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG79764.1 - 5.2e-21 75.2 0.0 8.1e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79764.1 - 1.9e-16 59.9 0.0 8.5e-16 57.8 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG79764.1 - 7.5e-11 42.3 0.1 1.6e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79764.1 - 1.9e-05 24.8 0.0 4.9e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG79764.1 - 0.015 15.3 0.0 0.061 13.4 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79764.1 - 0.13 12.5 0.1 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase HNH PF01844.23 GBG79765.1 - 3.8e-05 23.8 0.7 0.0001 22.4 0.7 1.8 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 GBG79765.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 GBG79765.1 - 0.0025 17.7 0.7 0.0055 16.5 0.2 1.9 2 1 0 2 2 2 1 HNH endonuclease DUF1681 PF07933.14 GBG79766.1 - 1.1e-55 187.4 0.0 1.4e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) RVT_1 PF00078.27 GBG79767.1 - 5.5e-31 107.8 0.1 7.4e-31 107.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79767.1 - 1.8e-12 47.2 0.0 7.9e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79767.1 - 0.0016 18.7 0.0 0.0036 17.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG79767.1 - 0.082 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 LAP1C PF05609.12 GBG79768.1 - 0.57 9.2 11.1 0.65 9.0 11.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SDA1 PF05285.12 GBG79768.1 - 0.61 9.5 23.1 0.77 9.1 23.1 1.1 1 0 0 1 1 1 0 SDA1 BAF1_ABF1 PF04684.13 GBG79768.1 - 0.64 9.0 12.8 0.75 8.8 12.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nop14 PF04147.12 GBG79768.1 - 1.2 7.3 19.9 1.5 6.9 19.9 1.2 1 0 0 1 1 1 0 Nop14-like family Roughex PF06020.11 GBG79768.1 - 1.7 7.7 13.5 2 7.4 13.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF2722 PF10846.8 GBG79768.1 - 2.3 7.0 9.3 2.6 6.9 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 GBG79768.1 - 3.9 5.6 18.5 4.9 5.3 18.5 1.1 1 0 0 1 1 1 0 CDC45-like protein LegC3_N PF18654.1 GBG79768.1 - 6.9 5.8 11.8 9.2 5.4 11.8 1.1 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain Hydrolase PF00702.26 GBG79769.1 - 2.3e-06 28.1 0.0 4.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GBG79769.1 - 0.00029 20.7 0.1 0.00044 20.1 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GBG79770.1 - 6.1e-41 139.9 3.9 6.1e-41 139.9 3.9 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GBG79770.1 - 2.2e-16 60.8 0.3 1.7e-15 57.9 0.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GBG79770.1 - 4.5e-12 45.5 0.0 2.1e-11 43.4 0.0 2.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GBG79770.1 - 4.7e-05 23.3 0.1 0.00077 19.3 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GBG79770.1 - 0.0011 19.0 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) MIF4G_like_2 PF09090.11 GBG79770.1 - 0.047 13.2 0.1 0.078 12.4 0.1 1.2 1 0 0 1 1 1 0 MIF4G like Ion_trans_2 PF07885.16 GBG79770.1 - 0.2 11.6 2.1 3.6 7.6 0.1 3.2 3 0 0 3 3 3 0 Ion channel RVT_1 PF00078.27 GBG79771.1 - 2.4e-29 102.4 0.1 4.7e-29 101.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79771.1 - 1e-15 57.6 0.0 4.7e-15 55.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79771.1 - 4.8e-07 30.0 0.0 1.9e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG79771.1 - 1.8e-06 28.5 0.0 3.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79771.1 - 1.9e-06 28.3 0.0 5.1e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG79771.1 - 2.9e-05 23.9 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG79771.1 - 0.007 16.2 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG79771.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TMF_TATA_bd PF12325.8 GBG79771.1 - 0.022 15.0 0.6 0.022 15.0 0.6 3.4 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Retrotrans_gag PF03732.17 GBG79771.1 - 2 8.8 5.9 6.3 7.1 0.2 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein E1-E2_ATPase PF00122.20 GBG79772.1 - 1e-40 139.2 3.7 1e-40 139.2 3.7 4.2 2 2 2 4 4 4 1 E1-E2 ATPase DUF659 PF04937.15 GBG79772.1 - 1.2e-11 44.7 1.3 1.7e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Cation_ATPase_N PF00690.26 GBG79772.1 - 3.1e-09 36.4 0.0 8.1e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GBG79772.1 - 0.0023 17.9 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GBG79772.1 - 0.0069 16.7 4.5 1.1 9.5 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase MIF4G_like_2 PF09090.11 GBG79772.1 - 0.4 10.1 3.4 0.12 11.8 0.1 1.7 2 0 0 2 2 2 0 MIF4G like Integrase_H2C2 PF17921.1 GBG79773.1 - 7.5e-18 64.4 0.3 1.8e-17 63.2 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG79773.1 - 3.2e-13 49.5 0.1 2.5e-07 30.6 0.0 2.9 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79773.1 - 1.7e-12 47.6 0.5 2.6e-10 40.5 0.2 3.0 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79773.1 - 4.4e-07 29.6 0.1 3.6e-06 26.7 0.0 2.3 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79773.1 - 4.4e-07 30.1 0.0 1.3e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Nop14 PF04147.12 GBG79775.1 - 0.0051 15.1 13.6 0.0053 15.1 13.6 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 GBG79775.1 - 0.0081 14.5 8.8 0.0095 14.3 8.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Sigma70_ner PF04546.13 GBG79775.1 - 0.041 13.8 9.0 0.058 13.3 9.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 GBG79775.1 - 0.052 12.9 10.1 0.052 12.9 10.1 1.2 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 GBG79775.1 - 0.26 10.7 14.4 0.33 10.3 14.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TbpB_B_D PF01298.18 GBG79775.1 - 0.3 11.5 3.5 0.35 11.3 2.7 1.6 1 1 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B YL1 PF05764.13 GBG79775.1 - 0.4 10.7 14.2 0.46 10.6 14.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 GBG79775.1 - 1.1 7.3 24.5 1.3 7.0 24.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi BIRC6 PF12356.8 GBG79775.1 - 2.2 7.7 5.1 3.3 7.1 5.1 1.3 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 TRAP_alpha PF03896.16 GBG79775.1 - 2.3 7.4 9.0 2.8 7.1 9.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pes-10 PF07149.11 GBG79775.1 - 3.2 6.7 17.3 4.1 6.4 17.3 1.1 1 0 0 1 1 1 0 Pes-10 RRN3 PF05327.11 GBG79775.1 - 4.1 5.8 15.6 4.7 5.6 15.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 GBG79775.1 - 5 5.1 11.1 5.2 5.0 11.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.9 GBG79775.1 - 9.6 5.2 23.7 12 4.9 23.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SBP PF03110.14 GBG79776.1 - 2.5e-23 82.2 8.5 5.7e-23 81.0 8.5 1.6 1 0 0 1 1 1 1 SBP domain Gly-rich_Ago1 PF12764.7 GBG79776.1 - 5.2 7.9 11.1 0.074 13.8 2.1 2.4 2 1 0 2 2 2 0 Glycine-rich region of argonaut Ion_trans PF00520.31 GBG79777.1 - 0.048 12.9 5.2 0.073 12.3 5.2 1.1 1 0 0 1 1 1 0 Ion transport protein Heliorhodopsin PF18761.1 GBG79777.1 - 0.9 8.8 7.0 1.4 8.2 7.0 1.2 1 0 0 1 1 1 0 Heliorhodopsin Ac81 PF05820.11 GBG79777.1 - 5.3 6.6 7.1 8.8 5.8 7.1 1.2 1 0 0 1 1 1 0 Baculoviridae AC81 Semialdhyde_dhC PF02774.18 GBG79778.1 - 1.2e-44 152.6 0.2 1.7e-44 152.1 0.2 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 GBG79778.1 - 2.4e-33 115.1 0.4 8.8e-33 113.3 0.1 2.1 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 GBG79778.1 - 0.086 12.4 0.3 0.21 11.2 0.1 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Semialdhyde_dhC PF02774.18 GBG79779.1 - 1.6e-44 152.2 0.2 2.5e-44 151.6 0.2 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 GBG79779.1 - 2.4e-33 115.2 0.4 8.7e-33 113.3 0.1 2.1 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 GBG79779.1 - 0.085 12.5 0.3 0.21 11.2 0.1 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Ribosomal_60s PF00428.19 GBG79781.1 - 0.49 11.0 8.2 1.2 9.8 8.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Na_trans_assoc PF06512.13 GBG79782.1 - 0.0055 17.0 5.4 0.0057 17.0 5.4 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated DUF2828 PF11443.8 GBG79782.1 - 0.012 13.7 0.0 0.013 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Mpp10 PF04006.12 GBG79782.1 - 0.016 13.7 16.8 0.025 13.0 16.8 1.3 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG79782.1 - 0.031 13.7 18.2 0.041 13.3 18.2 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG79782.1 - 0.034 12.8 14.1 0.042 12.4 14.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GBG79782.1 - 0.047 12.0 15.2 0.062 11.6 15.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 GBG79782.1 - 0.052 13.7 17.2 0.075 13.2 17.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FRQ PF09421.10 GBG79782.1 - 0.11 10.5 6.2 0.14 10.2 6.2 1.0 1 0 0 1 1 1 0 Frequency clock protein SAPS PF04499.15 GBG79782.1 - 0.11 11.2 3.2 0.13 11.0 3.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG79782.1 - 0.14 10.3 18.6 0.19 9.9 18.6 1.0 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.11 GBG79782.1 - 0.35 10.5 27.6 0.51 10.0 27.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4666 PF15697.5 GBG79782.1 - 0.69 10.6 6.6 0.41 11.4 4.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) VIR_N PF15912.5 GBG79782.1 - 1.7 8.2 12.1 2.4 7.7 12.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal BUD22 PF09073.10 GBG79782.1 - 2.1 7.6 19.2 2.9 7.1 19.2 1.1 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.7 GBG79782.1 - 3.5 5.7 7.7 4.3 5.3 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 GBG79782.1 - 4.6 6.4 6.8 6.6 5.9 6.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 GBG79782.1 - 5 5.8 8.3 6.5 5.4 8.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 GBG79782.1 - 5.7 5.8 5.1 8.4 5.3 5.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 GBG79782.1 - 6.2 6.6 14.7 9.2 6.0 14.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 GBG79782.1 - 7 6.0 18.4 9.9 5.5 18.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 GBG79782.1 - 7 5.3 13.1 9.7 4.8 13.1 1.1 1 0 0 1 1 1 0 Presenilin Flu_B_M2 PF04772.12 GBG79784.1 - 0.16 12.2 2.3 0.19 12.0 1.1 1.7 1 1 0 1 1 1 0 Influenza B matrix protein 2 (BM2) Pkinase_Tyr PF07714.17 GBG79785.1 - 2.4e-34 118.8 0.0 1.3e-22 80.3 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 GBG79785.1 - 3.6e-32 111.8 0.0 2e-31 109.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain LysM PF01476.20 GBG79785.1 - 1e-07 31.9 0.0 0.0073 16.4 0.0 3.4 3 0 0 3 3 3 3 LysM domain RT_RNaseH_2 PF17919.1 GBG79788.1 - 1.8e-28 98.5 0.0 2.6e-27 94.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79788.1 - 9.3e-25 87.4 0.0 1.6e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79788.1 - 4.3e-16 59.1 0.0 4.1e-15 56.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG79788.1 - 0.14 11.9 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease NOA36 PF06524.12 GBG79791.1 - 0.0015 17.9 13.6 0.0034 16.7 13.6 1.6 1 0 0 1 1 1 1 NOA36 protein Sigma70_ner PF04546.13 GBG79791.1 - 0.55 10.1 8.5 1 9.2 8.5 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 GBG79791.1 - 0.83 7.7 21.0 1.2 7.1 21.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 GBG79791.1 - 1.2 8.7 13.4 0.15 11.6 8.9 1.7 2 0 0 2 2 2 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 GBG79791.1 - 1.7 8.8 21.4 0.025 14.9 12.0 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 GCIP PF13324.6 GBG79791.1 - 3.1 7.3 7.7 4.7 6.8 7.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting SGT1 PF07093.11 GBG79791.1 - 3.6 5.9 8.1 5.3 5.4 8.1 1.1 1 0 0 1 1 1 0 SGT1 protein RRN3 PF05327.11 GBG79791.1 - 6.1 5.3 11.3 8.6 4.8 11.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 eIF3_subunit PF08597.10 GBG79792.1 - 0.013 15.5 26.7 0.013 15.5 26.7 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit K_channel_TID PF07941.11 GBG79792.1 - 0.097 13.1 5.9 0.27 11.7 5.9 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Vfa1 PF08432.10 GBG79792.1 - 0.44 10.8 60.0 1.3 9.4 28.4 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Spem1 PF15670.5 GBG79792.1 - 1.1 8.8 16.7 0.06 12.9 1.0 2.5 1 1 1 2 2 2 0 Spermatid maturation protein 1 DUF913 PF06025.12 GBG79792.1 - 2.4 7.0 27.9 0.25 10.3 9.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 GBG79792.1 - 3.4 7.4 61.3 4.6 7.0 23.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 GBG79792.1 - 9.5 6.3 60.7 2.8 8.1 30.3 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated MRP-L47 PF06984.13 GBG79793.1 - 1.8e-30 104.9 0.1 2.2e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 GBG79793.1 - 4.9e-09 36.0 0.0 7.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L29 protein IGPD PF00475.18 GBG79794.1 - 0.024 14.9 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase ubiquitin PF00240.23 GBG79794.1 - 0.05 13.3 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin family TFIIA PF03153.13 GBG79794.1 - 1.5 8.8 15.2 2.7 7.9 15.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ASH PF15780.5 GBG79795.1 - 1e-05 25.6 0.0 0.72 10.1 0.0 4.3 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 GBG79795.1 - 0.014 15.2 0.0 0.067 13.0 0.0 2.2 3 0 0 3 3 3 0 MSP (Major sperm protein) domain PapD-like PF14874.6 GBG79795.1 - 0.026 14.7 0.0 1 9.6 0.0 2.9 3 0 0 3 3 3 0 Flagellar-associated PapD-like GEN1_C PF18380.1 GBG79795.1 - 1.2 10.0 4.1 1.1 10.1 0.1 2.3 1 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain DUF659 PF04937.15 GBG79796.1 - 4.2e-36 124.1 0.0 1.7e-35 122.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) zf_C2H2_6 PF18450.1 GBG79796.1 - 0.16 11.7 0.3 0.4 10.4 0.3 1.7 1 0 0 1 1 1 0 Zinc Finger domain Myb_DNA-bind_4 PF13837.6 GBG79797.1 - 1.4e-07 31.8 8.6 2.3e-07 31.1 3.5 3.1 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG79797.1 - 0.082 13.0 4.6 0.14 12.2 2.6 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG79797.1 - 0.15 12.4 5.8 0.22 11.9 1.9 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2890 PF11081.8 GBG79797.1 - 0.21 11.7 1.8 0.5 10.5 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) GRP PF07172.11 GBG79797.1 - 0.69 10.6 15.0 1.4 9.6 0.8 2.7 2 0 0 2 2 2 0 Glycine rich protein family peroxidase PF00141.23 GBG79798.1 - 7.5e-46 156.7 0.0 1e-45 156.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Varsurf_PPLC PF03490.13 GBG79798.1 - 0.074 13.0 0.0 0.48 10.4 0.0 2.4 1 1 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C PseudoU_synth_1 PF01416.20 GBG79799.1 - 1.1e-37 128.7 0.1 1e-18 67.8 0.0 3.2 3 0 0 3 3 3 3 tRNA pseudouridine synthase ACOX PF01756.19 GBG79800.1 - 5.1e-39 133.7 0.4 9.5e-38 129.5 0.4 2.3 1 1 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GBG79800.1 - 6.4e-28 97.8 0.1 6.4e-28 97.8 0.1 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GBG79800.1 - 4.6e-14 52.4 0.0 1e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GBG79800.1 - 8.4e-05 22.8 5.4 0.0001 22.5 0.1 2.7 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain CDC45 PF02724.14 GBG79800.1 - 0.35 9.1 6.0 0.53 8.5 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG79800.1 - 1.6 6.8 8.5 2.7 6.1 8.5 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG79800.1 - 2 8.2 4.4 4.2 7.1 4.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 GBG79800.1 - 2.3 7.9 9.8 26 4.5 8.3 2.8 3 0 0 3 3 3 0 FAM176 family NOA36 PF06524.12 GBG79800.1 - 2.9 7.1 6.6 5.3 6.3 6.6 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG79800.1 - 8.3 4.4 11.5 13 3.8 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi PDZ_3 PF17815.1 GBG79801.1 - 2e-23 82.8 0.1 3.3e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 GBG79801.1 - 5.8e-22 79.2 0.7 1.4e-21 78.0 0.7 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GBG79801.1 - 2.3e-13 50.5 0.0 4.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 GBG79801.1 - 7.5e-06 26.2 0.1 0.0017 18.6 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 GBG79801.1 - 0.0093 16.3 0.0 0.27 11.6 0.0 3.0 3 0 0 3 3 3 1 PDZ domain ABC_tran PF00005.27 GBG79802.1 - 6.3e-32 111.0 0.0 1.2e-31 110.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GBG79802.1 - 1.5e-06 27.8 0.8 0.00048 19.6 0.3 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GBG79802.1 - 0.0027 17.8 0.0 0.0069 16.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 GBG79802.1 - 0.0056 16.4 0.1 0.014 15.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 GBG79802.1 - 0.011 15.8 0.2 0.03 14.4 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 GBG79802.1 - 0.014 15.6 0.1 0.086 13.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GBG79802.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 GBG79802.1 - 0.051 13.3 0.1 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 GBG79802.1 - 0.07 12.9 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GBG79802.1 - 0.075 13.5 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Orf78 PF06024.12 GBG79803.1 - 1.2 9.5 5.1 0.56 10.5 0.8 2.0 1 1 1 2 2 2 0 Orf78 (ac78) SDA1 PF05285.12 GBG79803.1 - 1.4 8.3 33.2 1.9 7.8 33.2 1.1 1 0 0 1 1 1 0 SDA1 DUF2615 PF11027.8 GBG79803.1 - 3.2 7.9 8.3 0.94 9.6 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) BUD22 PF09073.10 GBG79803.1 - 4.2 6.6 28.7 5.4 6.3 28.7 1.1 1 0 0 1 1 1 0 BUD22 Integrase_H2C2 PF17921.1 GBG79804.1 - 9.1e-20 70.5 0.1 1.5e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG79804.1 - 0.024 14.9 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG79804.1 - 0.072 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG79806.1 - 3.8e-46 155.2 0.0 9e-24 83.4 0.0 3.1 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase ABC_membrane PF00664.23 GBG79806.1 - 6.6e-40 137.5 20.0 2.6e-25 89.6 5.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region RT_RNaseH PF17917.1 GBG79806.1 - 4.6e-39 132.9 0.0 2.4e-18 66.3 0.0 3.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase ABC_tran PF00005.27 GBG79806.1 - 3.8e-20 72.8 0.0 3.8e-20 72.8 0.0 4.1 5 1 0 5 5 3 1 ABC transporter RVT_1 PF00078.27 GBG79806.1 - 2.4e-14 53.4 0.4 7.1e-06 25.7 0.1 3.6 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 GBG79806.1 - 2.6e-07 30.3 1.0 7.4e-07 28.9 0.1 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.17 GBG79806.1 - 0.0014 18.8 0.0 0.0014 18.8 0.0 6.0 7 0 0 7 7 6 1 Retrotransposon gag protein SMC_N PF02463.19 GBG79806.1 - 0.036 13.5 0.8 0.29 10.5 0.6 2.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GBG79806.1 - 0.072 13.0 0.0 0.33 10.8 0.0 2.1 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 GBG79806.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG79806.1 - 0.45 10.9 0.0 0.45 10.9 0.0 3.6 3 1 0 3 3 2 0 AAA ATPase domain DUF659 PF04937.15 GBG79807.1 - 2.4e-29 102.2 0.9 4.2e-29 101.4 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Death PF00531.22 GBG79807.1 - 0.058 13.6 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Death domain Med26 PF08711.11 GBG79807.1 - 0.064 13.3 0.2 0.25 11.4 0.2 2.0 1 0 0 1 1 1 0 TFIIS helical bundle-like domain SSXT PF05030.12 GBG79807.1 - 0.18 11.5 0.2 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 SSXT protein (N-terminal region) TFIIA PF03153.13 GBG79808.1 - 0.7 9.8 11.7 0.92 9.4 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TspO_MBR PF03073.15 GBG79811.1 - 7e-46 155.6 22.5 8.6e-46 155.3 22.5 1.0 1 0 0 1 1 1 1 TspO/MBR family Retrotrans_gag PF03732.17 GBG79812.1 - 5e-05 23.5 0.3 0.0011 19.1 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG79812.1 - 0.001 19.6 0.0 0.0019 18.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79812.1 - 0.0018 18.8 0.0 0.0038 17.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Ldl_recept_a PF00057.18 GBG79814.1 - 3.8e-47 158.2 114.3 2.6e-08 33.9 8.0 11.2 11 0 0 11 11 11 10 Low-density lipoprotein receptor domain class A RT_RNaseH_2 PF17919.1 GBG79816.1 - 4.1e-32 110.2 0.1 9.6e-32 109.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79816.1 - 8.4e-29 99.9 0.1 1.9e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG79816.1 - 0.00023 21.0 0.0 0.00065 19.6 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG79816.1 - 0.0053 17.0 0.1 0.023 14.9 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain CDV3 PF15359.6 GBG79816.1 - 0.16 12.5 1.1 0.46 11.0 0.1 2.1 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Ku PF02735.16 GBG79817.1 - 1.5e-41 142.4 0.0 2.2e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 GBG79817.1 - 8.2e-13 48.6 0.0 2e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_C PF03730.14 GBG79817.1 - 0.036 14.8 0.5 0.1 13.3 0.1 2.0 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm rve PF00665.26 GBG79819.1 - 5.7e-07 29.7 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG79819.1 - 0.04 13.6 0.1 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) LRR_6 PF13516.6 GBG79820.1 - 1.9e-11 43.1 20.1 0.16 12.1 0.1 10.5 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.7 GBG79820.1 - 8.8e-09 35.5 0.7 0.81 10.2 0.0 6.6 6 2 2 8 8 8 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 GBG79820.1 - 0.00012 21.9 0.3 0.00012 21.9 0.3 3.5 4 0 0 4 4 4 1 F-box-like LRR_1 PF00560.33 GBG79820.1 - 0.00038 20.6 14.0 9.5 7.2 0.0 9.0 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.6 GBG79820.1 - 0.00041 20.1 2.8 1.3 8.8 0.1 5.6 3 2 2 5 5 5 1 Leucine rich repeat F-box_5 PF18511.1 GBG79820.1 - 0.00073 19.1 0.1 0.0015 18.0 0.1 1.5 1 0 0 1 1 1 1 F-box DUF3950 PF13132.6 GBG79820.1 - 0.14 11.9 0.2 0.37 10.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) Preseq_ALAS PF09029.10 GBG79820.1 - 1.6 9.2 4.8 78 3.8 0.1 3.5 3 0 0 3 3 3 0 5-aminolevulinate synthase presequence zf-BED PF02892.15 GBG79823.1 - 0.1 12.7 1.3 0.18 11.8 1.3 1.4 1 0 0 1 1 1 0 BED zinc finger zf-CCHC_2 PF13696.6 GBG79824.1 - 3.1e-05 23.7 4.5 4.8e-05 23.1 4.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG79824.1 - 9.5e-05 22.3 2.4 0.00015 21.7 2.4 1.3 1 0 0 1 1 1 1 Zinc knuckle Myb_DNA-binding PF00249.31 GBG79825.1 - 8.6e-08 32.3 0.0 2.1e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3050 PF11251.8 GBG79825.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) SDA1 PF05285.12 GBG79825.1 - 1.5 8.1 24.0 2.2 7.6 24.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG79825.1 - 8.5 4.5 20.4 12 4.1 20.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG79826.1 - 3.6e-28 98.6 0.1 6.3e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG79826.1 - 3.8e-06 27.4 0.1 8.7e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG79826.1 - 9.7e-06 25.4 0.0 2.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79826.1 - 4.6e-05 24.0 0.0 0.00019 22.0 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Chromo PF00385.24 GBG79826.1 - 0.00068 19.5 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG79826.1 - 0.0012 19.1 0.5 0.0066 16.7 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Herpes_BLRF2 PF05812.12 GBG79826.1 - 0.019 15.1 0.1 0.048 13.8 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Prp19 PF08606.11 GBG79826.1 - 0.17 11.9 1.6 0.5 10.4 1.0 2.1 2 0 0 2 2 2 0 Prp19/Pso4-like RT_RNaseH_2 PF17919.1 GBG79827.1 - 7e-28 96.6 0.0 1.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79827.1 - 8.3e-25 87.1 0.0 1.5e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79827.1 - 1e-17 64.0 1.9 1.9e-17 63.1 0.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG79827.1 - 9.7e-11 41.6 0.6 1.9e-08 34.1 0.2 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79827.1 - 1e-06 28.9 0.0 2.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79827.1 - 0.0022 18.2 0.0 0.01 16.0 0.1 2.2 2 0 0 2 2 2 1 H2C2 zinc finger DUF1870 PF08965.10 GBG79828.1 - 0.035 14.1 4.4 0.43 10.6 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1870) DUF3752 PF12572.8 GBG79828.1 - 1.4 9.4 11.8 2.9 8.4 11.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF1664 PF07889.12 GBG79828.1 - 1.7 8.7 7.3 0.24 11.4 0.3 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) RT_RNaseH_2 PF17919.1 GBG79829.1 - 1.1e-33 115.3 0.0 1.9e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79829.1 - 3.5e-32 111.7 0.1 6.3e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79829.1 - 3.7e-29 101.1 0.0 6.8e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1758 PF05585.12 GBG79829.1 - 0.00096 19.0 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG79829.1 - 0.035 14.7 0.0 0.082 13.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG79829.1 - 0.041 14.4 0.0 0.16 12.5 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG79829.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG79830.1 - 1e-26 92.9 0.0 2.1e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79830.1 - 4.6e-25 87.9 0.0 9.4e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79830.1 - 1.6e-17 63.3 0.4 5.5e-17 61.6 0.4 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG79830.1 - 6.6e-11 42.1 0.2 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79830.1 - 7.3e-10 39.1 0.0 1.8e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Metallophos PF00149.28 GBG79830.1 - 1.1e-07 32.6 0.0 2.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase gag-asp_proteas PF13975.6 GBG79830.1 - 1.4e-05 25.5 0.0 2.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79830.1 - 2e-05 25.2 0.0 3.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79830.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF2052 PF09747.9 GBG79830.1 - 0.0078 16.4 3.9 0.0078 16.4 3.9 2.5 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) DUF4366 PF14283.6 GBG79830.1 - 0.012 15.7 2.9 0.86 9.6 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) SapB_2 PF03489.17 GBG79830.1 - 0.025 14.7 0.1 0.049 13.7 0.1 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 2 zf-H2C2 PF09337.10 GBG79830.1 - 0.037 14.3 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG79830.1 - 0.051 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease PTPRCAP PF15713.5 GBG79830.1 - 5.5 7.3 25.7 1.8 8.9 13.5 3.0 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated Jnk-SapK_ap_N PF09744.9 GBG79831.1 - 0.0092 16.2 1.5 0.0092 16.2 1.5 2.1 2 1 0 2 2 2 1 JNK_SAPK-associated protein-1 DUF3347 PF11827.8 GBG79831.1 - 0.16 12.2 0.2 0.27 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) TPR_MLP1_2 PF07926.12 GBG79831.1 - 1.9 8.6 7.9 2.4 8.2 6.6 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein gag-asp_proteas PF13975.6 GBG79832.1 - 1.5e-07 31.9 0.3 8e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79832.1 - 7.3e-05 23.3 0.0 0.0002 21.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG79832.1 - 0.0011 19.3 0.0 0.0031 17.8 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG79832.1 - 0.0029 17.4 0.7 0.0057 16.4 0.7 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF4795 PF16043.5 GBG79832.1 - 0.13 11.9 0.1 0.35 10.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Agouti PF05039.12 GBG79832.1 - 1.8 9.4 4.8 1.2 9.9 1.7 2.4 2 0 0 2 2 2 0 Agouti protein Zn-ribbon_8 PF09723.10 GBG79832.1 - 1.9 8.7 6.8 1 9.6 1.3 3.2 3 0 0 3 3 3 0 Zinc ribbon domain RT_RNaseH PF17917.1 GBG79833.1 - 4.7e-22 78.3 0.0 9.8e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79833.1 - 3.5e-20 71.9 0.0 9.5e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79833.1 - 1e-12 47.9 0.1 3.3e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG79833.1 - 3.5e-06 26.7 0.0 7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79833.1 - 2.5e-05 24.5 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG79833.1 - 0.0018 18.8 0.2 0.0061 17.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79833.1 - 0.012 16.2 0.0 0.033 14.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG79833.1 - 0.013 15.8 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein RXLR PF16810.5 GBG79833.1 - 1.4 9.4 3.0 2.6 8.5 3.0 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity PGA2 PF07543.12 GBG79833.1 - 6 6.9 12.2 27 4.7 12.2 2.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Ribosomal_L9_N PF01281.19 GBG79834.1 - 2.5e-15 55.7 0.0 5.4e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 GBG79834.1 - 1.4e-07 31.8 0.0 3.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain tRNA-Thr_ED PF08915.11 GBG79834.1 - 0.036 14.1 0.1 0.053 13.6 0.1 1.2 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase DUF1685 PF07939.11 GBG79834.1 - 0.18 11.6 0.0 0.6 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) ABC2_membrane_3 PF12698.7 GBG79836.1 - 0.051 12.7 2.8 0.064 12.4 2.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Dimer_Tnp_hAT PF05699.14 GBG79837.1 - 1.2e-05 25.0 0.6 2.5e-05 24.0 0.6 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Mito_carr PF00153.27 GBG79838.1 - 2.8e-69 229.1 13.2 9.8e-25 86.3 0.4 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein Serine_protease PF18405.1 GBG79838.1 - 0.24 10.5 2.0 1.5 7.9 0.1 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease LEP503 PF15221.6 GBG79838.1 - 3.1 8.2 6.7 2.4 8.5 0.6 3.5 4 0 0 4 4 4 0 Lens epithelial cell protein LEP503 ASFV_J13L PF05568.11 GBG79838.1 - 5.6 6.7 7.0 1.5 8.5 3.5 1.8 2 0 0 2 2 2 0 African swine fever virus J13L protein SPA PF08616.10 GBG79840.1 - 1.9e-06 27.8 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis zf_CCCH_4 PF18345.1 GBG79841.1 - 4.1e-08 33.0 10.7 5.7e-06 26.2 6.9 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GBG79841.1 - 3.3e-07 29.9 11.7 2.8e-06 27.0 5.6 2.9 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 GBG79841.1 - 3.9e-06 26.6 5.6 0.0004 20.2 2.7 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) BUD22 PF09073.10 GBG79841.1 - 0.0048 16.3 33.6 0.0048 16.3 33.6 3.6 3 0 0 3 3 3 1 BUD22 zf-CCHC PF00098.23 GBG79842.1 - 5.5e-05 23.0 2.9 9.2e-05 22.3 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle Trimer_CC PF08954.11 GBG79842.1 - 0.031 13.8 5.7 0.082 12.5 1.0 3.6 3 0 0 3 3 3 0 Trimerisation motif DUF484 PF04340.12 GBG79842.1 - 0.046 13.4 1.2 0.069 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF484 TolA_bind_tri PF16331.5 GBG79842.1 - 0.068 13.2 7.2 1 9.5 0.3 4.0 3 2 1 4 4 4 0 TolA binding protein trimerisation PikAIV_N PF18605.1 GBG79842.1 - 0.8 9.3 7.6 4.4 7.0 2.6 3.0 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain SlyX PF04102.12 GBG79842.1 - 1.7 9.3 16.3 1.8 9.2 0.1 5.1 4 2 1 5 5 5 0 SlyX zf-CCHC_2 PF13696.6 GBG79842.1 - 4.1 7.3 6.0 6.5 6.7 6.0 1.3 1 0 0 1 1 1 0 Zinc knuckle PsbR PF04725.12 GBG79844.1 - 1.9e-33 114.7 1.6 3e-33 114.1 1.6 1.3 1 0 0 1 1 1 1 Photosystem II 10 kDa polypeptide PsbR RVT_1 PF00078.27 GBG79844.1 - 2e-28 99.5 0.1 3.3e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79844.1 - 1.5e-16 60.2 0.0 3.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79844.1 - 0.00029 21.1 0.0 0.00065 20.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SET PF00856.28 GBG79845.1 - 0.0019 18.6 1.5 0.016 15.6 0.1 2.9 2 1 0 2 2 2 1 SET domain YL1 PF05764.13 GBG79845.1 - 0.019 15.1 28.4 0.066 13.3 11.9 2.5 2 0 0 2 2 2 0 YL1 nuclear protein NUFIP1 PF10453.9 GBG79845.1 - 0.072 12.9 0.0 0.072 12.9 0.0 2.5 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) SDA1 PF05285.12 GBG79846.1 - 0.0015 18.0 25.6 0.0017 17.9 25.6 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GBG79846.1 - 0.017 14.5 32.2 0.024 14.0 32.2 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG79846.1 - 0.32 9.1 31.0 0.4 8.8 31.0 1.1 1 0 0 1 1 1 0 Nop14-like family Coilin_N PF15862.5 GBG79846.1 - 0.39 10.5 5.1 0.6 9.9 5.1 1.5 1 0 0 1 1 1 0 Coilin N-terminus Astro_capsid_p PF12226.8 GBG79846.1 - 0.58 9.3 16.6 0.79 8.8 16.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TFIIF_alpha PF05793.12 GBG79846.1 - 1.3 7.5 32.8 1.9 7.0 32.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 GBG79846.1 - 1.9 8.2 23.6 2.9 7.5 23.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Raftlin PF15250.6 GBG79846.1 - 2.2 7.0 12.4 2.8 6.6 12.4 1.3 1 0 0 1 1 1 0 Raftlin Zip PF02535.22 GBG79846.1 - 2.6 7.2 9.2 3.5 6.8 9.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 GBG79846.1 - 4.1 6.7 7.5 9 5.6 7.5 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NPR3 PF03666.13 GBG79846.1 - 5.9 5.6 11.5 6.9 5.3 11.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GREB1 PF15782.5 GBG79846.1 - 6.7 3.7 11.3 8 3.4 11.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HSP70 PF00012.20 GBG79846.1 - 8.6 4.4 10.5 8.7 4.4 10.5 1.1 1 0 0 1 1 1 0 Hsp70 protein LAP1C PF05609.12 GBG79846.1 - 8.7 5.3 19.3 12 4.9 19.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 GBG79847.1 - 0.082 11.7 2.5 0.11 11.3 2.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 GBG79847.1 - 0.63 8.5 7.0 0.88 8.1 7.0 1.1 1 0 0 1 1 1 0 Macoilin family RVT_1 PF00078.27 GBG79848.1 - 1.7e-05 24.4 0.1 2.5e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YL1 PF05764.13 GBG79848.1 - 0.023 14.8 9.2 0.029 14.5 9.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GBG79848.1 - 0.32 9.2 11.1 0.37 8.9 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG79848.1 - 0.44 8.8 10.1 0.56 8.4 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG79848.1 - 0.92 8.9 11.4 1.1 8.6 11.4 1.1 1 0 0 1 1 1 0 SDA1 Pkinase_Tyr PF07714.17 GBG79849.1 - 4.7e-31 108.0 0.0 1.3e-30 106.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG79849.1 - 9.7e-31 107.1 0.6 2e-30 106.1 0.0 1.8 2 0 0 2 2 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG79849.1 - 1.6e-29 101.9 0.0 4.1e-29 100.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79849.1 - 3.9e-29 101.0 0.1 9.7e-29 99.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79849.1 - 1.3e-18 66.8 0.6 3e-18 65.6 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG79849.1 - 3.9e-11 42.9 0.0 8.8e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG79849.1 - 3.8e-06 26.7 0.0 7.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79849.1 - 7.1e-06 26.6 0.0 1.8e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG79849.1 - 0.00021 21.5 0.0 0.00062 20.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG79849.1 - 0.00049 20.6 0.0 0.0016 18.9 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG79849.1 - 0.0017 18.6 0.1 0.0041 17.3 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG79849.1 - 0.009 15.8 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Usp PF00582.26 GBG79849.1 - 0.035 14.6 0.1 0.035 14.6 0.1 4.1 4 0 0 4 4 2 0 Universal stress protein family rve PF00665.26 GBG79850.1 - 1.2e-06 28.7 0.0 2.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG79850.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LYTB PF02401.18 GBG79851.1 - 1e-79 267.5 0.0 1.5e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 LytB protein RT_RNaseH_2 PF17919.1 GBG79851.1 - 3.7e-31 107.1 0.0 8.3e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79851.1 - 1.3e-28 100.1 0.1 2.1e-28 99.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79851.1 - 1.2e-26 93.1 0.1 2.2e-26 92.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79851.1 - 9.1e-21 73.7 0.8 2.8e-19 69.0 0.5 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG79851.1 - 0.0008 19.6 0.0 0.0025 18.0 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG79852.1 - 9.6e-30 103.7 0.1 1.5e-29 103.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79852.1 - 3e-09 37.1 0.1 2.1e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG79852.1 - 0.044 14.4 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Pkinase PF00069.25 GBG79853.1 - 1.1e-59 202.0 0.0 2.1e-59 201.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79853.1 - 2.7e-43 148.1 0.0 4.9e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG79853.1 - 1.4e-05 24.1 0.0 1.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GBG79853.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GBG79853.1 - 0.0046 16.0 0.0 0.0046 16.0 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 GBG79853.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Trypan_PARP PF05887.11 GBG79853.1 - 0.048 13.6 11.1 0.22 11.5 11.1 2.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) APH PF01636.23 GBG79853.1 - 0.14 12.1 0.0 0.14 12.1 0.0 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family NARP1 PF12569.8 GBG79853.1 - 7 5.4 14.3 2.2 7.1 0.1 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RVT_1 PF00078.27 GBG79855.1 - 8.7e-24 84.3 0.1 1.6e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79855.1 - 1.2e-17 63.8 0.5 3.9e-17 62.1 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG79855.1 - 3.8e-15 55.8 0.0 2e-14 53.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79855.1 - 4.1e-09 36.7 0.4 1.3e-05 25.4 0.0 3.6 3 1 1 4 4 4 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG79855.1 - 4.3e-08 33.7 0.0 1.8e-07 31.7 0.0 2.1 2 0 0 2 2 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79855.1 - 1.1e-07 31.7 0.0 2.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG79855.1 - 1.1e-07 32.0 0.0 5.1e-07 29.9 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG79855.1 - 1.3e-06 28.9 0.0 5.1e-06 27.0 0.0 2.1 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG79855.1 - 0.00027 20.7 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG79855.1 - 0.0053 17.0 5.1 0.0099 16.1 0.0 3.6 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG79855.1 - 0.019 14.9 0.1 0.053 13.5 0.1 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DivIC PF04977.15 GBG79855.1 - 1.4 8.7 5.1 2.8 7.8 1.9 2.9 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 GBG79855.1 - 3 7.1 16.1 1.3 8.3 6.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG79856.1 - 1.5e-32 112.9 0.1 2.9e-32 112.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79856.1 - 9.2e-29 99.4 0.0 1.8e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79856.1 - 2.9e-26 91.8 0.3 5.4e-26 90.9 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79856.1 - 3.1e-15 56.0 0.5 8.7e-15 54.6 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79856.1 - 1e-14 54.7 0.0 2.4e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79856.1 - 0.00053 20.2 0.0 0.0017 18.5 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger CK2S PF15011.6 GBG79858.1 - 1.1e-29 103.4 0.4 1.3e-29 103.2 0.4 1.0 1 0 0 1 1 1 1 Casein Kinase 2 substrate DUF3437 PF11919.8 GBG79858.1 - 0.076 12.9 0.4 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Pept_tRNA_hydro PF01195.19 GBG79859.1 - 6e-54 182.5 0.0 1.4e-53 181.4 0.0 1.6 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase RVT_1 PF00078.27 GBG79859.1 - 2.9e-12 46.6 0.0 4.8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAM-associated PF14303.6 GBG79859.1 - 0.11 13.2 1.3 5.2 7.8 0.0 2.9 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain SbcCD_C PF13558.6 GBG79859.1 - 4.7 7.5 5.4 3.1 8.1 1.9 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SLC35F PF06027.12 GBG79860.1 - 2.6e-94 316.1 21.6 3.2e-94 315.8 21.6 1.0 1 0 0 1 1 1 1 Solute carrier family 35 UAA PF08449.11 GBG79860.1 - 3.8e-08 32.9 8.1 6.9e-08 32.0 8.2 1.4 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 GBG79860.1 - 2.1e-07 30.2 6.0 4.7e-07 29.1 4.8 1.9 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GBG79860.1 - 0.00044 20.4 35.4 0.0036 17.5 14.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family Acyltransferase PF01553.21 GBG79861.1 - 1.5e-25 89.3 0.0 3.6e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Adap_comp_sub PF00928.21 GBG79862.1 - 2.7e-11 43.4 0.0 6.6e-07 29.0 0.0 2.2 1 1 1 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GBG79862.1 - 0.0071 16.3 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2242 PF10001.9 GBG79862.1 - 0.034 14.3 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) Oxidored_q3 PF00499.20 GBG79863.1 - 0.13 11.9 4.9 0.45 10.2 0.7 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Conotoxin PF02950.17 GBG79863.1 - 4.6 8.3 5.9 14 6.8 1.8 2.6 2 1 1 3 3 3 0 Conotoxin DNA_pol_phi PF04931.13 GBG79863.1 - 5 5.1 15.4 6.3 4.8 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Paramyxo_ncap PF00973.19 GBG79863.1 - 5.7 5.7 11.3 6.9 5.5 11.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein UPF0239 PF06783.11 GBG79863.1 - 9.5 6.5 8.5 1.2 9.4 2.0 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0239) RT_RNaseH PF17917.1 GBG79864.1 - 1.4e-24 86.4 0.0 4.7e-24 84.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79864.1 - 2.2e-24 85.4 0.0 6.3e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase C2 PF00168.30 GBG79864.1 - 2.7e-17 62.9 0.5 5.5e-16 58.7 0.1 2.5 2 0 0 2 2 2 1 C2 domain Integrase_H2C2 PF17921.1 GBG79864.1 - 1e-15 57.5 0.6 4.1e-15 55.6 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain SMP_LBD PF17047.5 GBG79864.1 - 3.6e-11 42.9 0.2 5.7e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain RVT_1 PF00078.27 GBG79864.1 - 0.0076 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG79864.1 - 0.008 16.4 0.1 0.018 15.2 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Glyco_hydro_2_N PF02837.18 GBG79864.1 - 0.023 14.6 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Retrotrans_gag PF03732.17 GBG79864.1 - 0.039 14.2 0.1 0.039 14.2 0.1 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein Solute_trans_a PF03619.16 GBG79866.1 - 4.1e-60 203.6 19.2 4.6e-60 203.4 19.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Histone PF00125.24 GBG79867.1 - 7.5e-26 91.0 0.2 7.5e-26 91.0 0.2 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Myb_DNA-bind_4 PF13837.6 GBG79868.1 - 2.2e-07 31.2 0.6 6.3e-07 29.7 0.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG79868.1 - 0.0005 20.1 0.4 0.0013 18.7 0.4 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SPC22 PF04573.12 GBG79869.1 - 0.0082 15.6 2.6 0.01 15.3 2.6 1.1 1 0 0 1 1 1 1 Signal peptidase subunit ABC2_membrane_3 PF12698.7 GBG79869.1 - 0.24 10.5 9.4 0.29 10.2 9.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1676 PF07898.13 GBG79869.1 - 0.38 10.8 9.5 0.47 10.5 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Amnionless PF14828.6 GBG79869.1 - 0.91 8.3 3.0 1 8.1 3.0 1.1 1 0 0 1 1 1 0 Amnionless Myb_DNA-bind_4 PF13837.6 GBG79870.1 - 7.5e-08 32.7 0.5 1.3e-07 31.9 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG79870.1 - 0.0074 16.6 0.4 0.017 15.4 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like EIN3 PF04873.13 GBG79871.1 - 2.5e-120 400.5 10.3 3.5e-120 400.0 10.3 1.2 1 0 0 1 1 1 1 Ethylene insensitive 3 DUF2841 PF11001.8 GBG79871.1 - 1.7e-05 24.9 0.8 1.7e-05 24.9 0.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2841) Exo_endo_phos PF03372.23 GBG79873.1 - 0.00068 19.2 0.0 0.0023 17.5 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nop14 PF04147.12 GBG79874.1 - 8.7 4.4 21.8 9.8 4.2 21.8 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG79876.1 - 0.18 11.1 31.5 0.28 10.5 31.5 1.2 1 0 0 1 1 1 0 BUD22 Na_trans_assoc PF06512.13 GBG79876.1 - 0.23 11.7 17.5 0.8 10.0 17.5 1.9 1 1 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG79876.1 - 0.91 8.9 30.7 1.1 8.6 30.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG79876.1 - 1.3 7.1 29.7 1.5 6.9 29.7 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG79876.1 - 2.3 6.7 26.9 3.2 6.2 26.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF45 PF01863.17 GBG79877.1 - 0.003 17.6 10.7 0.014 15.5 6.8 2.7 2 1 0 2 2 2 1 Protein of unknown function DUF45 Med5 PF08689.10 GBG79877.1 - 0.03 12.1 0.3 0.034 12.0 0.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit Med5 DUF4211 PF13926.6 GBG79877.1 - 1.2 9.2 5.2 2.2 8.3 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) LMBR1 PF04791.16 GBG79877.1 - 1.9 7.3 8.6 2.5 6.9 8.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein hDGE_amylase PF14701.6 GBG79877.1 - 4.2 6.3 7.7 7.1 5.6 7.7 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF826 PF05696.11 GBG79877.1 - 5.8 7.1 6.6 29 4.8 0.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF826) rve PF00665.26 GBG79878.1 - 3.8e-18 65.8 0.1 1.6e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG79878.1 - 2e-14 53.4 0.0 4.5e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG79878.1 - 0.0025 18.0 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Miff PF05644.11 GBG79878.1 - 0.17 11.5 8.3 0.29 10.7 8.3 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff UPF0184 PF03670.13 GBG79878.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) DAG_kinase_N PF14513.6 GBG79878.1 - 0.27 11.4 4.5 0.093 12.9 1.3 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF2407_C PF13373.6 GBG79878.1 - 0.42 10.8 2.7 0.95 9.6 2.7 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain CCDC53 PF10152.9 GBG79878.1 - 2 8.8 14.6 0.08 13.4 1.5 2.3 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Iron_permease PF04120.12 GBG79878.1 - 2.1 8.1 8.3 0.25 11.1 3.5 1.9 2 0 0 2 2 2 0 Low affinity iron permease Plasmid_RAQPRD PF09686.10 GBG79878.1 - 4.9 7.4 10.1 0.66 10.2 1.2 3.5 4 0 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) RVT_1 PF00078.27 GBG79879.1 - 4.6e-35 121.2 0.1 8.3e-35 120.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79879.1 - 4.2e-28 97.7 0.1 9.8e-28 96.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79879.1 - 1.7e-27 95.4 0.0 5.1e-27 93.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79879.1 - 4.3e-18 65.2 0.8 9.8e-18 64.0 0.8 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG79879.1 - 4.8e-08 32.9 0.0 8.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79879.1 - 8.6e-07 29.5 0.1 5.2e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79879.1 - 8e-05 23.1 0.1 0.0013 19.2 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG79879.1 - 0.0007 19.4 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF1564 PF07600.11 GBG79879.1 - 0.009 15.7 0.0 0.057 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Asp_protease PF09668.10 GBG79879.1 - 0.01 15.6 0.0 0.035 13.9 0.0 1.9 2 0 0 2 2 1 0 Aspartyl protease rve PF00665.26 GBG79879.1 - 0.011 15.9 0.0 0.044 14.0 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain PLD_C PF12357.8 GBG79879.1 - 0.017 15.0 0.0 1.5 8.8 0.0 2.8 2 0 0 2 2 2 0 Phospholipase D C terminal PA26 PF04636.13 GBG79879.1 - 1.7 7.4 10.2 3.7 6.4 10.2 1.6 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CP12 PF02672.15 GBG79880.1 - 0.013 16.2 0.8 0.042 14.6 0.8 1.9 1 1 0 1 1 1 0 CP12 domain RVT_1 PF00078.27 GBG79881.1 - 5.7e-33 114.3 0.1 9e-33 113.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79881.1 - 1.5e-14 53.8 0.1 9.5e-14 51.3 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG79881.1 - 5.2e-12 46.0 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG79881.1 - 1.2e-07 31.6 0.0 3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79881.1 - 9.8e-05 22.9 0.0 0.00033 21.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG79881.1 - 0.00011 22.7 0.0 0.00089 19.8 0.0 2.6 3 0 0 3 3 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG79881.1 - 0.00049 19.9 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG79881.1 - 0.0085 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger CCDC85 PF10226.9 GBG79881.1 - 0.039 13.6 0.6 0.087 12.5 0.6 1.6 1 0 0 1 1 1 0 CCDC85 family HALZ PF02183.18 GBG79881.1 - 0.44 10.8 2.3 1.4 9.2 2.3 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 GBG79881.1 - 0.81 9.8 12.0 0.22 11.6 4.0 3.1 3 0 0 3 3 3 0 Basic region leucine zipper YscO PF07321.12 GBG79881.1 - 0.86 9.5 12.1 2.5 8.0 12.1 1.7 1 0 0 1 1 1 0 Type III secretion protein YscO bZIP_1 PF00170.21 GBG79881.1 - 4.5 7.4 7.2 0.95 9.6 2.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor RVT_1 PF00078.27 GBG79882.1 - 8.5e-27 94.1 0.0 1.6e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG79882.1 - 1.1e-07 32.3 0.0 6.1e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79882.1 - 1.7e-07 31.8 0.0 4.8e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG79882.1 - 5.5e-06 26.2 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG79882.1 - 4.8e-05 23.1 0.0 9.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG79882.1 - 0.0016 18.7 2.3 0.015 15.6 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG79882.1 - 0.25 10.6 5.2 0.56 9.5 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 GBG79882.1 - 6.9 7.0 8.1 45 4.3 5.4 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RraA-like PF03737.15 GBG79883.1 - 0.045 13.9 1.1 0.13 12.4 0.4 2.0 2 0 0 2 2 2 0 Aldolase/RraA BNR_2 PF13088.6 GBG79884.1 - 2.1e-07 30.5 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain Retrotrans_gag PF03732.17 GBG79884.1 - 0.0028 17.9 0.3 0.0056 16.9 0.3 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotrans_gag PF03732.17 GBG79885.1 - 0.0017 18.6 0.3 0.0034 17.6 0.3 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein SIR4_SID PF16991.5 GBG79886.1 - 3.1 7.8 12.7 6.8 6.7 4.2 2.4 2 0 0 2 2 2 0 Sir4 SID domain BNR_2 PF13088.6 GBG79887.1 - 2.1e-36 125.7 0.0 3.5e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain DUF4185 PF13810.6 GBG79887.1 - 0.017 14.4 0.3 3.9 6.6 0.0 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4185) BNR PF02012.20 GBG79887.1 - 0.021 14.8 13.2 7.6 7.0 0.9 5.5 5 0 0 5 5 5 0 BNR/Asp-box repeat Ammonium_transp PF00909.21 GBG79889.1 - 1.9e-131 438.4 34.0 1.9e-131 438.4 34.0 1.4 2 0 0 2 2 2 1 Ammonium Transporter Family RT_RNaseH_2 PF17919.1 GBG79890.1 - 6.1e-68 225.1 0.1 2e-33 114.4 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79890.1 - 8.1e-59 196.4 0.7 4e-28 97.8 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79890.1 - 1.4e-36 124.3 1.8 7.3e-18 64.4 0.0 2.9 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG79890.1 - 1.1e-33 116.7 0.1 2.7e-32 112.1 0.1 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG79890.1 - 1.7e-17 63.7 0.0 1.7e-13 50.8 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain gag-asp_proteas PF13975.6 GBG79890.1 - 2.2e-08 34.5 0.3 2.1e-07 31.4 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79890.1 - 2.2e-05 25.0 0.0 6.5e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG79890.1 - 7.5e-05 22.9 0.3 0.15 12.3 0.1 2.9 2 0 0 2 2 2 2 H2C2 zinc finger DUF1758 PF05585.12 GBG79890.1 - 0.0082 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG79890.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Mcp5_PH PF12814.7 GBG79890.1 - 0.15 12.2 2.5 4.5 7.4 0.3 2.6 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology RVT_1 PF00078.27 GBG79892.1 - 2.3e-33 115.6 0.0 4.5e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG79892.1 - 4.1e-17 62.4 0.0 7.8e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain rve PF00665.26 GBG79892.1 - 3.2e-16 59.6 0.0 6.9e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Abhydrolase_6 PF12697.7 GBG79892.1 - 8.4e-09 36.4 1.1 8.4e-09 36.4 1.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG79892.1 - 5.9e-08 32.7 0.0 1.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold cNMP_binding PF00027.29 GBG79892.1 - 3.9e-05 23.6 0.0 0.00016 21.7 0.0 2.1 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 GBG79892.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Hydrolase_4 PF12146.8 GBG79892.1 - 0.0027 17.0 0.2 0.71 9.1 0.0 2.7 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 GBG79892.1 - 0.055 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative esterase CCDC85 PF10226.9 GBG79892.1 - 0.16 11.6 0.2 1 9.0 0.3 2.1 2 0 0 2 2 2 0 CCDC85 family DivIC PF04977.15 GBG79892.1 - 0.32 10.8 2.1 1 9.2 2.1 1.8 1 0 0 1 1 1 0 Septum formation initiator DED PF01335.21 GBG79892.1 - 0.48 10.7 2.4 14 6.1 0.1 2.8 2 0 0 2 2 2 0 Death effector domain RVT_1 PF00078.27 GBG79893.1 - 6.9e-31 107.5 0.0 1.3e-30 106.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG79893.1 - 5.3e-26 91.0 0.8 1.3e-25 89.7 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79893.1 - 1.9e-24 85.6 0.1 1.3e-23 82.9 0.1 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG79893.1 - 0.064 12.9 0.1 0.064 12.9 0.1 3.3 2 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase cNMP_binding PF00027.29 GBG79894.1 - 1e-21 76.8 0.4 1.6e-09 37.7 0.0 4.2 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Retrotrans_gag PF03732.17 GBG79895.1 - 0.015 15.5 3.0 0.015 15.5 3.0 2.9 2 2 1 3 3 3 0 Retrotransposon gag protein Rab_bind PF16704.5 GBG79895.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Rab binding domain ERM PF00769.19 GBG79895.1 - 0.39 10.5 27.6 0.85 9.4 27.6 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Herpes_UL17 PF04559.12 GBG79895.1 - 1.3 7.7 12.1 2 7.2 12.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein XRN_M PF17846.1 GBG79895.1 - 6.7 5.5 8.6 10 4.9 8.6 1.3 1 0 0 1 1 1 0 Xrn1 helical domain RVT_1 PF00078.27 GBG79896.1 - 8.3e-26 90.9 0.1 1.1e-25 90.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 GBG79897.1 - 6.2e-10 38.7 0.1 1.1e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Atg29_N PF18388.1 GBG79897.1 - 1.1 9.1 5.2 2.7 7.9 0.3 2.8 1 1 1 2 2 2 0 Atg29 N-terminal domain RNase_PH PF01138.21 GBG79898.1 - 2.5e-34 118.6 0.0 1.1e-15 58.3 0.0 2.7 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GBG79898.1 - 4.4e-14 52.3 0.6 7.9e-10 38.6 0.1 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.14 GBG79898.1 - 1e-09 38.8 0.1 1.5e-05 25.4 0.0 2.5 2 0 0 2 2 2 2 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_1 PF00013.29 GBG79898.1 - 6.3e-07 29.1 0.6 1.7e-06 27.7 0.6 1.7 1 0 0 1 1 1 1 KH domain gag-asp_proteas PF13975.6 GBG79900.1 - 2e-05 25.0 0.0 4.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79900.1 - 4.8e-05 23.9 0.0 0.0001 22.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG79900.1 - 0.0033 17.0 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG79900.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG79901.1 - 3.1e-06 27.0 4.0 6.3e-06 26.0 4.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG79901.1 - 0.13 12.0 0.9 0.28 10.9 0.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG79901.1 - 0.18 11.7 4.4 0.33 10.8 4.4 1.4 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.29 GBG79902.1 - 3e-48 163.9 0.0 6.9e-48 162.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG79902.1 - 2e-28 99.0 0.0 6e-28 97.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 GBG79902.1 - 3.2e-14 53.0 0.0 6.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 GBG79902.1 - 9.1e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG79902.1 - 0.002 17.5 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 GBG79902.1 - 0.0055 16.0 0.0 0.0085 15.3 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase TPR_2 PF07719.17 GBG79903.1 - 7.5e-22 75.6 26.3 0.00015 21.6 0.4 10.9 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 GBG79903.1 - 2.4e-17 62.0 20.5 0.0058 16.4 0.4 9.8 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 GBG79903.1 - 3.9e-16 58.2 1.0 0.022 15.1 0.0 8.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG79903.1 - 2.4e-13 50.4 23.1 0.15 12.6 0.0 9.4 7 3 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 GBG79903.1 - 2.1e-11 44.2 28.2 0.074 13.7 0.2 9.8 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 GBG79903.1 - 2.9e-11 43.2 28.2 0.69 10.9 0.0 11.1 8 3 4 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.6 GBG79903.1 - 2.3e-10 39.8 13.6 3.5 7.9 0.0 9.9 11 1 0 11 11 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG79903.1 - 6.8e-10 38.4 8.9 0.017 15.3 0.1 8.2 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG79903.1 - 3e-07 30.0 9.6 5.8 6.7 0.0 7.8 7 1 1 8 8 8 1 TPR repeat ANAPC3 PF12895.7 GBG79903.1 - 5.6e-07 29.7 9.9 0.18 12.0 0.0 6.6 8 1 0 9 9 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GBG79903.1 - 2.2e-06 27.9 21.8 0.0078 16.5 0.9 8.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.6 GBG79903.1 - 1.1e-05 25.7 4.1 0.0072 16.6 0.0 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 GBG79903.1 - 0.023 14.4 0.1 0.42 10.3 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 GBG79903.1 - 0.058 14.0 20.9 23 5.9 0.1 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG79903.1 - 0.083 12.8 14.1 13 5.8 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG79903.1 - 0.089 12.9 20.5 0.11 12.7 0.2 6.6 5 2 2 7 7 7 0 Tetratricopeptide repeat MRP-S23 PF10484.9 GBG79904.1 - 0.0057 16.9 0.1 0.01 16.1 0.1 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 MRP-S25 PF13741.6 GBG79904.1 - 0.0078 15.8 9.2 0.13 11.8 0.0 3.0 1 1 2 3 3 3 2 Mitochondrial ribosomal protein S25 Pectinesterase PF01095.19 GBG79905.1 - 1.4e-60 204.6 1.4 1.8e-60 204.2 1.4 1.0 1 0 0 1 1 1 1 Pectinesterase RVT_1 PF00078.27 GBG79907.1 - 1.1e-20 74.2 0.1 1.8e-20 73.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79907.1 - 1.1e-14 54.2 0.5 3.6e-14 52.6 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG79907.1 - 2.9e-13 50.0 0.0 5.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain SDA1 PF05285.12 GBG79907.1 - 9.7e-05 21.9 13.3 0.00013 21.5 13.3 1.1 1 0 0 1 1 1 1 SDA1 zf-H2C2 PF09337.10 GBG79907.1 - 0.00024 21.3 0.1 0.00058 20.0 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG79907.1 - 0.00052 20.6 0.0 0.00099 19.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF4366 PF14283.6 GBG79907.1 - 3.3 7.7 4.8 9.1 6.3 4.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) NPR3 PF03666.13 GBG79907.1 - 8 5.1 14.4 15 4.2 14.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RVP_2 PF08284.11 GBG79908.1 - 0.041 13.7 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease Na_trans_assoc PF06512.13 GBG79908.1 - 6.1 7.1 21.1 13 6.0 21.1 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated Plasmodium_Vir PF05795.11 GBG79908.1 - 9.4 5.5 8.9 14 5.0 8.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Topo_Zn_Ribbon PF08272.11 GBG79909.1 - 0.015 14.9 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG79909.1 - 0.18 12.0 1.9 0.31 11.2 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Pectinesterase PF01095.19 GBG79910.1 - 1.3e-64 217.8 5.9 1.6e-64 217.5 5.9 1.1 1 0 0 1 1 1 1 Pectinesterase RVT_1 PF00078.27 GBG79912.1 - 7.3e-32 110.7 0.0 1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4399 PF14347.6 GBG79912.1 - 0.052 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Dabb PF07876.12 GBG79913.1 - 1.4e-12 48.1 0.0 1.6e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3425 PF11905.8 GBG79913.1 - 0.23 11.5 0.1 0.33 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) RVT_1 PF00078.27 GBG79914.1 - 5.5e-32 111.1 0.1 8.8e-32 110.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79914.1 - 1.1e-16 60.7 0.0 3e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79914.1 - 0.00017 21.8 0.0 0.00045 20.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1079 PF06435.11 GBG79914.1 - 0.14 12.4 1.6 14 6.1 0.3 2.7 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) MMR1 PF08505.10 GBG79915.1 - 0.043 14.1 25.2 0.11 12.8 25.2 1.8 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SLC12 PF03522.15 GBG79915.1 - 0.073 12.1 34.5 0.18 10.8 34.5 1.6 1 0 0 1 1 1 0 Solute carrier family 12 DUF262 PF03235.14 GBG79915.1 - 0.29 11.3 17.2 0.56 10.4 17.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF262 Apt1 PF10351.9 GBG79915.1 - 0.44 9.3 24.8 0.96 8.2 24.8 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain SID-1_RNA_chan PF13965.6 GBG79915.1 - 0.93 7.8 9.0 1.9 6.8 9.0 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 GBG79915.1 - 0.96 8.1 36.1 0.042 12.6 28.7 2.2 2 0 0 2 2 2 0 Presenilin Endostatin PF06482.11 GBG79915.1 - 3.2 7.1 18.6 7.6 5.9 18.6 1.6 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin AF-4 PF05110.13 GBG79915.1 - 6.2 4.8 54.5 14 3.6 54.5 1.6 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Nop14 PF04147.12 GBG79915.1 - 9 4.4 54.5 3.2 5.9 2.9 2.2 2 0 0 2 2 2 0 Nop14-like family DDE_Tnp_4 PF13359.6 GBG79916.1 - 1.6e-31 109.1 0.0 1e-30 106.5 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG79916.1 - 5.9e-14 52.2 0.0 9.8e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG79916.1 - 1.7e-05 24.6 0.3 0.21 11.2 0.3 2.4 2 0 0 2 2 2 2 Transposase DDE domain Pkinase PF00069.25 GBG79918.1 - 2.1e-35 122.4 0.0 2.7e-22 79.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79918.1 - 3.7e-35 121.4 0.0 3.4e-33 115.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG79918.1 - 9.4e-05 21.4 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG79918.1 - 0.0014 18.6 0.0 0.025 14.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_60s PF00428.19 GBG79918.1 - 0.099 13.2 0.0 0.099 13.2 0.0 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein ParA PF10609.9 GBG79920.1 - 9.2e-83 277.5 0.1 1.3e-82 277.0 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 GBG79920.1 - 4.3e-17 62.0 0.0 1.1e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 GBG79920.1 - 3.4e-12 46.5 0.0 6.7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GBG79920.1 - 4.3e-10 39.8 1.2 8.2e-09 35.6 1.2 2.1 1 1 0 1 1 1 1 AAA domain DUF971 PF06155.12 GBG79920.1 - 5.2e-08 33.4 0.1 1.7e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) MipZ PF09140.11 GBG79920.1 - 2.6e-06 26.9 0.1 6.5e-06 25.6 0.1 1.7 1 1 0 1 1 1 1 ATPase MipZ VirC1 PF07015.11 GBG79920.1 - 0.00034 20.0 0.0 0.00054 19.3 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein Fer4_NifH PF00142.18 GBG79920.1 - 0.0046 16.4 0.2 0.0091 15.5 0.2 1.5 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 GBG79920.1 - 0.0068 15.6 0.6 0.025 13.8 0.2 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 GBG79920.1 - 0.027 13.9 0.2 0.082 12.4 0.1 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ CAP_GLY PF01302.25 GBG79921.1 - 5.6e-22 77.5 3.3 9.3e-22 76.8 3.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 GBG79921.1 - 1.1e-20 73.9 0.0 1.7e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Mito_carr PF00153.27 GBG79922.1 - 1e-53 179.2 12.7 4.9e-18 64.8 1.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 GBG79922.1 - 0.0022 18.2 1.2 0.058 13.6 0.4 3.1 3 1 1 4 4 4 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF5336 PF17270.2 GBG79922.1 - 0.0044 16.7 0.1 0.031 13.9 0.0 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5336) SNARE_assoc PF09335.11 GBG79922.1 - 0.41 11.1 5.5 2 8.9 0.2 3.4 4 0 0 4 4 4 0 SNARE associated Golgi protein RT_RNaseH PF17917.1 GBG79924.1 - 3.5e-29 101.2 0.0 7.1e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79924.1 - 3.3e-27 94.4 0.0 7e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG79924.1 - 3.5e-13 49.4 0.1 8.8e-13 48.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC_4 PF14392.6 GBG79924.1 - 0.00062 19.4 0.1 0.0018 18.0 0.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG79924.1 - 0.02 14.7 1.3 0.056 13.3 1.3 1.8 1 0 0 1 1 1 0 Zinc knuckle MS_channel PF00924.18 GBG79924.1 - 0.034 13.7 3.7 1.3 8.6 0.0 3.1 3 0 0 3 3 3 0 Mechanosensitive ion channel RVT_1 PF00078.27 GBG79924.1 - 0.068 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_tran_Xtn PF12848.7 GBG79924.1 - 0.22 11.6 2.9 0.61 10.1 2.9 1.8 1 0 0 1 1 1 0 ABC transporter zf-CCHC PF00098.23 GBG79924.1 - 0.34 11.1 3.2 1.1 9.5 3.2 1.9 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 GBG79925.1 - 8.5e-39 133.5 0.0 5.8e-25 88.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79925.1 - 9.2e-39 133.3 0.0 5.9e-37 127.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GBG79925.1 - 3.5e-05 23.9 0.1 0.0002 21.4 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG79925.1 - 0.00022 20.1 0.0 0.00035 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Shisa PF13908.6 GBG79925.1 - 0.0031 17.8 0.0 3.3 7.9 0.0 2.3 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator Ribosomal_60s PF00428.19 GBG79925.1 - 0.083 13.5 0.5 0.47 11.1 0.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein EphA2_TM PF14575.6 GBG79925.1 - 0.17 12.8 0.0 13 6.7 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.12 GBG79925.1 - 1.5 9.2 10.9 0.02 15.3 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) zf-CCHC PF00098.23 GBG79926.1 - 4.2e-08 32.9 2.7 1.6e-07 31.1 2.7 2.1 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG79926.1 - 0.00075 19.4 0.9 0.0022 17.9 0.9 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG79926.1 - 0.041 13.6 0.7 0.12 12.1 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG79926.1 - 0.043 13.7 1.2 0.098 12.5 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle V_ATPase_I PF01496.19 GBG79926.1 - 0.88 7.4 5.8 1 7.2 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1943 PF09172.11 GBG79926.1 - 2.8 7.1 8.9 3.8 6.7 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) SOBP PF15279.6 GBG79926.1 - 4.1 7.9 8.2 5.7 7.4 8.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein VIR_N PF15912.5 GBG79926.1 - 8.1 6.0 9.5 14 5.2 9.5 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal AAA_11 PF13086.6 GBG79926.1 - 9.2 6.0 15.1 15 5.2 15.1 1.3 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 GBG79926.1 - 9.6 4.4 15.8 12 4.0 15.8 1.2 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG79927.1 - 6.7e-20 71.0 0.0 1.3e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79927.1 - 2.8e-18 66.1 0.0 6.9e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79927.1 - 3e-08 33.5 0.0 5.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SlyX PF04102.12 GBG79927.1 - 0.024 15.3 3.3 0.19 12.4 0.0 3.7 3 0 0 3 3 3 0 SlyX RT_RNaseH_2 PF17919.1 GBG79928.1 - 4.7e-20 71.5 0.0 1.1e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79928.1 - 2.9e-18 66.1 0.0 6.1e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG79928.1 - 1.5e-08 35.0 0.0 3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG79928.1 - 2.6e-08 33.7 0.0 4.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG79928.1 - 2.1e-06 28.3 0.0 4.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79928.1 - 0.00076 19.3 0.1 0.0015 18.3 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG79928.1 - 0.017 15.4 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease SlyX PF04102.12 GBG79928.1 - 0.031 14.9 0.7 0.17 12.5 0.0 2.7 2 0 0 2 2 2 0 SlyX RT_RNaseH_2 PF17919.1 GBG79929.1 - 2.4e-28 98.1 0.0 4.2e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79929.1 - 2.1e-23 82.6 0.0 4.1e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79929.1 - 4.2e-09 36.2 0.1 6.7e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG79929.1 - 0.42 8.8 6.3 0.52 8.5 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG79929.1 - 1.3 7.2 7.1 1.8 6.8 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG79929.1 - 1.9 7.8 9.1 2.8 7.3 9.1 1.1 1 0 0 1 1 1 0 SDA1 Choline_transpo PF04515.12 GBG79930.1 - 9.5e-53 179.5 0.0 2.4e-52 178.2 0.0 1.7 2 0 0 2 2 2 1 Plasma-membrane choline transporter Mit_proteolip PF08039.11 GBG79930.1 - 0.27 11.7 6.2 12 6.5 0.1 3.6 4 0 0 4 4 4 0 Mitochondrial proteolipid RVT_1 PF00078.27 GBG79931.1 - 2.4e-14 53.4 0.0 4.7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG79931.1 - 1.2e-05 25.1 2.2 2e-05 24.4 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG79931.1 - 0.008 16.0 2.3 0.014 15.2 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG79931.1 - 0.0089 16.3 0.0 0.046 14.0 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Pkinase_Tyr PF07714.17 GBG79932.1 - 7.2e-33 114.0 0.0 9.9e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG79932.1 - 2.9e-32 112.1 0.0 9.2e-19 67.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 GBG79932.1 - 2.9e-05 23.0 0.0 4.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG79932.1 - 0.043 13.7 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family RCC1 PF00415.18 GBG79934.1 - 3e-61 203.9 31.8 2.9e-13 50.2 4.0 9.9 9 1 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG79934.1 - 1.7e-33 113.7 47.2 6e-08 32.3 0.0 9.7 10 0 0 10 10 10 8 Regulator of chromosome condensation (RCC1) repeat Reg_prop PF07494.11 GBG79934.1 - 0.037 14.2 0.1 22 5.7 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller Pkinase PF00069.25 GBG79935.1 - 8.4e-25 87.6 0.0 2e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79935.1 - 4.2e-23 81.9 0.0 1.4e-10 40.9 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase SKG6 PF08693.10 GBG79935.1 - 0.1 12.0 6.2 0.33 10.4 5.3 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain HTH_28 PF13518.6 GBG79935.1 - 0.13 12.4 0.1 3.5 7.8 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain VEGFR-2_TMD PF17988.1 GBG79935.1 - 0.42 10.1 4.1 1.1 8.7 4.1 1.7 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Dimer_Tnp_hAT PF05699.14 GBG79937.1 - 0.099 12.4 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Cwf_Cwc_15 PF04889.12 GBG79937.1 - 3.3 7.4 11.2 0.53 10.0 5.8 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 GBG79938.1 - 3.4e-35 121.7 0.0 4.5e-22 78.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG79938.1 - 3.5e-35 121.6 0.0 3.1e-33 115.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG79938.1 - 6e-05 22.0 0.0 9.8e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG79938.1 - 0.0038 17.2 0.0 0.064 13.2 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_60s PF00428.19 GBG79938.1 - 0.096 13.3 0.0 0.096 13.3 0.0 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein BCIP PF13862.6 GBG79940.1 - 2.6e-55 187.4 7.3 9.9e-46 156.1 0.8 2.7 2 1 0 2 2 2 2 p21-C-terminal region-binding protein RVT_1 PF00078.27 GBG79940.1 - 2.5e-33 115.5 0.1 4.8e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG79940.1 - 3.4e-23 81.6 0.0 1.3e-22 79.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79940.1 - 1.7e-11 44.3 0.0 5.1e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MFS_1 PF07690.16 GBG79941.1 - 4.7e-19 68.5 39.2 8.9e-10 38.0 19.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GBG79941.1 - 0.00059 18.8 6.3 0.0041 16.0 6.3 2.4 1 1 0 1 1 1 1 MFS_1 like family Sporozoite_P67 PF05642.11 GBG79941.1 - 0.002 16.3 1.4 0.002 16.3 1.4 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen ATG22 PF11700.8 GBG79941.1 - 0.026 13.2 0.5 0.026 13.2 0.5 3.2 4 0 0 4 4 4 0 Vacuole effluxer Atg22 like Saf_2TM PF18303.1 GBG79941.1 - 0.035 13.7 0.7 0.085 12.4 0.0 2.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF3720 PF12517.8 GBG79941.1 - 0.39 11.7 13.8 0.77 10.7 13.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) DUF485 PF04341.12 GBG79941.1 - 0.57 10.2 0.0 0.57 10.2 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Zw10 PF06248.13 GBG79942.1 - 1.1e-55 189.3 0.0 4.4e-34 118.0 0.0 5.4 5 0 0 5 5 5 5 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 GBG79942.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal YqzE PF14038.6 GBG79942.1 - 0.18 11.9 0.6 12 5.9 0.0 2.4 2 0 0 2 2 2 0 YqzE-like protein FSA_C PF10479.9 GBG79942.1 - 0.84 7.7 2.5 1.3 7.0 2.5 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF659 PF04937.15 GBG79943.1 - 2.7e-34 118.2 0.0 6.3e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4407 PF14362.6 GBG79943.1 - 7.9 5.7 10.7 13 5.0 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) dCache_1 PF02743.18 GBG79945.1 - 0.025 14.4 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Cache domain D123 PF07065.14 GBG79945.1 - 0.69 9.0 5.0 1.2 8.2 5.0 1.3 1 0 0 1 1 1 0 D123 TRAP_alpha PF03896.16 GBG79945.1 - 3.7 6.7 6.5 0.67 9.1 1.7 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit D123 PF07065.14 GBG79946.1 - 0.41 9.8 5.0 0.77 8.9 5.0 1.3 1 0 0 1 1 1 0 D123 TRAP_alpha PF03896.16 GBG79946.1 - 0.94 8.6 5.7 0.31 10.2 1.3 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Trypan_PARP PF05887.11 GBG79946.1 - 4.1 7.4 19.8 0.47 10.4 0.2 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RVT_1 PF00078.27 GBG79947.1 - 1.4e-26 93.4 0.1 8.1e-24 84.4 0.0 3.0 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79947.1 - 1.2e-18 67.0 0.1 2.7e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79947.1 - 1.7e-07 31.4 0.0 5.3e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG79947.1 - 3.2e-05 23.7 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG79947.1 - 0.00015 22.3 0.0 0.00034 21.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG79947.1 - 0.00063 19.7 2.1 0.00063 19.7 2.1 2.9 3 0 0 3 3 3 1 Zinc knuckle DUF4187 PF13821.6 GBG79947.1 - 0.0096 15.7 0.5 0.036 13.8 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG79947.1 - 0.015 15.6 2.9 0.22 11.8 0.0 3.7 4 1 0 4 4 4 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG79947.1 - 0.023 15.3 0.0 0.065 13.8 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Mt_ATP-synt_B PF05405.14 GBG79947.1 - 6.3 6.4 9.0 16 5.1 8.6 2.0 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-CCHC PF00098.23 GBG79948.1 - 7.2e-05 22.7 2.1 0.00016 21.6 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG79948.1 - 0.017 14.6 0.0 2.8 7.4 0.0 2.3 1 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4_5 PF17121.5 GBG79948.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 GBG79948.1 - 0.2 11.6 2.2 2.1 8.4 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3292 PF11696.8 GBG79948.1 - 0.79 8.0 5.8 1.1 7.6 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF4192 PF13830.6 GBG79948.1 - 7.4 6.5 12.5 34 4.4 12.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) DUF4187 PF13821.6 GBG79949.1 - 0.002 17.9 0.6 0.0055 16.5 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Astro_capsid_p PF12226.8 GBG79949.1 - 0.0046 16.2 14.0 0.011 14.9 14.0 1.6 1 0 0 1 1 1 1 Turkey astrovirus capsid protein DUF4407 PF14362.6 GBG79949.1 - 0.39 10.0 8.6 1.1 8.5 8.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop14 PF04147.12 GBG79949.1 - 0.88 7.7 14.6 0.24 9.6 6.9 2.2 2 0 0 2 2 2 0 Nop14-like family PPP4R2 PF09184.11 GBG79949.1 - 1.1 8.7 11.2 0.021 14.4 1.4 2.6 3 0 0 3 3 3 0 PPP4R2 RT_RNaseH_2 PF17919.1 GBG79950.1 - 1.8e-19 69.6 0.0 3.2e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79950.1 - 6.7e-11 42.4 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79950.1 - 2.5e-08 33.7 0.1 3.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG79950.1 - 0.025 14.0 23.7 0.032 13.7 23.7 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG79950.1 - 0.075 12.4 21.5 0.096 12.0 21.5 1.2 1 0 0 1 1 1 0 BUD22 Nop53 PF07767.11 GBG79950.1 - 0.2 11.0 21.4 0.3 10.4 21.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cwf_Cwc_15 PF04889.12 GBG79950.1 - 0.21 11.3 22.3 0.32 10.7 22.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG79950.1 - 0.42 8.8 25.9 0.57 8.3 25.9 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG79950.1 - 0.92 8.2 7.6 1.2 7.9 7.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.10 GBG79950.1 - 1.1 9.6 11.7 1.7 8.9 11.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 GBG79950.1 - 4 5.6 21.3 5.7 5.1 21.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 GBG79950.1 - 4.3 6.9 10.0 6.1 6.5 10.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Lin-8 PF03353.15 GBG79950.1 - 6.3 6.3 16.3 9.9 5.6 16.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2358 PF10184.9 GBG79951.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) BORCS6 PF10157.9 GBG79951.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DFRP_C PF16543.5 GBG79952.1 - 9.3e-18 64.5 4.9 9.3e-18 64.5 4.9 3.6 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 GBG79952.1 - 1.1e-05 26.1 15.6 0.00022 21.9 4.2 3.9 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 GBG79952.1 - 0.00023 21.0 2.5 0.00023 21.0 2.5 2.9 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GBG79952.1 - 0.00062 19.5 3.4 0.00062 19.5 3.4 3.0 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GBG79952.1 - 0.012 15.6 7.9 0.012 15.6 7.9 3.2 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 GBG79952.1 - 0.5 10.6 5.6 0.72 10.1 0.7 2.7 1 1 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 GBG79952.1 - 4 8.1 11.0 3.8 8.1 4.4 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 GBG79953.1 - 2.8e-20 71.7 17.3 2.2e-11 43.4 3.7 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG79953.1 - 1.1e-09 38.0 17.7 4.5e-05 23.3 2.8 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 GBG79953.1 - 2.3e-07 30.5 10.3 0.0015 18.2 1.2 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GBG79953.1 - 1.4 9.5 13.6 0.63 10.6 2.0 2.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GBG79953.1 - 6.6 7.5 9.4 2.1 9.1 1.1 2.8 1 1 1 2 2 2 0 Torus domain Integrase_H2C2 PF17921.1 GBG79954.1 - 1.1e-13 51.1 0.2 2.4e-13 50.0 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG79954.1 - 1.9e-09 37.8 0.0 4.8e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG79954.1 - 4.9e-08 32.7 0.0 9.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG79954.1 - 3.8e-06 27.4 0.0 9.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79954.1 - 0.00065 20.3 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG79954.1 - 0.002 18.4 8.5 0.002 18.4 8.5 2.1 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 Asp_protease PF09668.10 GBG79954.1 - 0.012 15.4 0.6 0.023 14.5 0.6 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG79954.1 - 0.023 14.9 0.6 0.054 13.7 0.6 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Kinesin PF00225.23 GBG79956.1 - 9.5e-98 327.2 0.1 9.5e-98 327.2 0.1 2.9 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GBG79956.1 - 7.6e-22 77.8 0.0 7.6e-22 77.8 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding CopK PF11525.8 GBG79956.1 - 0.045 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Copper resistance protein K DSPc PF00782.20 GBG79959.1 - 5.2e-05 23.1 0.1 9.4e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 GBG79959.1 - 0.0069 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GBG79959.1 - 0.015 14.9 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GBG79959.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 GBG79959.1 - 0.22 11.1 0.2 0.36 10.5 0.2 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TPR_4 PF07721.14 GBG79960.1 - 2.5e-05 24.5 1.4 0.081 13.6 0.3 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat PPR_3 PF13812.6 GBG79960.1 - 8e-05 22.6 0.4 0.6 10.2 0.0 3.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG79960.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG79960.1 - 0.00057 20.4 0.1 2.3 8.8 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG79960.1 - 0.0023 18.6 1.8 3.1 8.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 GBG79960.1 - 0.0099 16.1 1.9 1.2 9.5 0.0 3.3 4 0 0 4 4 4 1 PPR repeat PknG_TPR PF16918.5 GBG79960.1 - 0.012 14.4 0.0 0.44 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat PPR_2 PF13041.6 GBG79960.1 - 0.021 15.0 0.0 1.8 8.8 0.0 3.1 2 0 0 2 2 2 0 PPR repeat family Clp_N PF02861.20 GBG79960.1 - 0.044 13.9 0.3 0.11 12.7 0.3 1.7 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component Thg1C PF14413.6 GBG79960.1 - 0.74 10.0 3.8 1.4 9.1 3.8 1.4 1 0 0 1 1 1 0 Thg1 C terminal domain DUF809 PF05663.11 GBG79960.1 - 3.1 7.9 6.4 15 5.7 7.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Pkinase_Tyr PF07714.17 GBG79962.1 - 6.9e-31 107.5 0.0 1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG79962.1 - 1.6e-30 106.4 0.0 2.4e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain MATH PF00917.26 GBG79962.1 - 1.4e-23 83.2 0.0 7.2e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 MATH domain USP7_ICP0_bdg PF12436.8 GBG79962.1 - 2.3e-22 79.5 0.0 5.4e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 U-box PF04564.15 GBG79962.1 - 3.6e-17 62.3 0.0 9.3e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GBG79962.1 - 0.00067 19.4 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Spc7 PF08317.11 GBG79962.1 - 0.024 13.5 1.2 0.039 12.8 1.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TetR_C_24 PF17932.1 GBG79963.1 - 0.036 14.3 0.0 0.037 14.3 0.0 1.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1515 PF07439.11 GBG79963.1 - 0.075 13.1 0.1 0.093 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) BRK PF07533.16 GBG79963.1 - 0.4 10.4 2.8 7.4 6.3 0.3 2.2 2 0 0 2 2 2 0 BRK domain PTPRCAP PF15713.5 GBG79964.1 - 0.0051 17.1 16.3 0.0066 16.7 16.3 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG79964.1 - 0.012 14.0 8.8 0.012 13.9 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Usp PF00582.26 GBG79964.1 - 0.02 15.4 9.7 0.033 14.7 9.7 1.3 1 0 0 1 1 1 0 Universal stress protein family RNA_pol_Rpc4 PF05132.14 GBG79964.1 - 0.026 15.0 2.3 0.034 14.6 2.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC27 PF09507.10 GBG79964.1 - 0.059 12.8 13.8 0.072 12.5 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Na_trans_assoc PF06512.13 GBG79964.1 - 0.097 12.9 15.4 0.11 12.7 15.4 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2072 PF09845.9 GBG79964.1 - 0.16 12.2 8.8 0.21 11.8 8.8 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF5308 PF17233.2 GBG79964.1 - 0.19 12.0 4.4 0.21 11.8 4.4 1.2 1 1 0 1 1 1 0 Family of unknown function (DUF5308) DUF740 PF05340.12 GBG79964.1 - 0.21 10.3 16.9 0.26 10.0 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) V_ATPase_I PF01496.19 GBG79964.1 - 0.45 8.4 2.3 0.43 8.4 2.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mpp10 PF04006.12 GBG79964.1 - 0.49 8.8 22.5 0.59 8.5 22.5 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 GBG79964.1 - 0.53 9.2 4.0 0.55 9.1 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4366 PF14283.6 GBG79964.1 - 0.59 10.2 10.0 0.84 9.7 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) GNAT_acetyltr_2 PF13718.6 GBG79964.1 - 0.64 9.4 4.8 0.86 9.0 4.8 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 SID-1_RNA_chan PF13965.6 GBG79964.1 - 0.64 8.4 1.1 0.73 8.2 1.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Afi1 PF07792.12 GBG79964.1 - 0.73 10.3 7.9 0.98 9.9 7.9 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4045 PF13254.6 GBG79964.1 - 0.81 9.3 5.2 0.88 9.1 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Paf1 PF03985.13 GBG79964.1 - 0.82 8.6 23.0 1 8.3 23.0 1.1 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 GBG79964.1 - 0.99 8.7 18.8 1.2 8.5 18.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 GBG79964.1 - 1 8.7 23.1 1.3 8.4 23.1 1.0 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG79964.1 - 1.1 8.0 5.6 1.3 7.7 5.6 1.1 1 0 0 1 1 1 0 Presenilin PPL5 PF18168.1 GBG79964.1 - 1.3 8.3 6.9 1.9 7.7 6.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 PA26 PF04636.13 GBG79964.1 - 1.5 7.6 5.4 1.8 7.4 5.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.12 GBG79964.1 - 1.5 8.6 15.0 1.9 8.2 15.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3984 PF13136.6 GBG79964.1 - 2.2 7.6 9.4 2.4 7.5 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) GRP PF07172.11 GBG79964.1 - 2.3 9.0 31.2 1.2e+02 3.4 31.2 2.4 1 1 0 1 1 1 0 Glycine rich protein family Connexin PF00029.19 GBG79964.1 - 2.4 7.8 5.8 3.4 7.4 5.8 1.2 1 0 0 1 1 1 0 Connexin Drc1-Sld2 PF11719.8 GBG79964.1 - 2.7 7.4 11.4 3.7 7.0 11.4 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 GBG79964.1 - 4.1 5.5 24.1 5 5.2 24.1 1.0 1 0 0 1 1 1 0 Nop14-like family MDM1 PF15501.6 GBG79964.1 - 4.1 6.4 14.0 5.2 6.1 14.0 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 DUF3306 PF11748.8 GBG79964.1 - 5.1 8.0 12.1 7.6 7.4 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) BUD22 PF09073.10 GBG79964.1 - 7.1 5.9 18.3 9 5.5 18.3 1.1 1 0 0 1 1 1 0 BUD22 VIT1 PF01988.19 GBG79964.1 - 9.1 6.1 7.3 14 5.5 7.3 1.3 1 0 0 1 1 1 0 VIT family Cwf_Cwc_15 PF04889.12 GBG79964.1 - 9.6 5.9 17.8 12 5.5 17.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MCM PF00493.23 GBG79965.1 - 5.2e-99 329.9 0.1 8.8e-99 329.1 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain RT_RNaseH_2 PF17919.1 GBG79965.1 - 1.6e-65 217.4 0.1 5.7e-34 116.1 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG79965.1 - 8.6e-53 177.1 0.0 2.6e-30 104.8 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG79965.1 - 4.3e-30 104.9 0.1 6.9e-30 104.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MCM_OB PF17207.3 GBG79965.1 - 5.1e-29 100.7 0.2 1.4e-28 99.3 0.2 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 GBG79965.1 - 6.7e-16 58.8 1.1 2.1e-15 57.2 0.4 2.3 2 0 0 2 2 1 1 MCM N-terminal domain MCM_lid PF17855.1 GBG79965.1 - 1.7e-07 31.5 0.2 5.8e-07 29.8 0.2 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GBG79965.1 - 2.3e-07 30.4 0.0 4.1e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GBG79965.1 - 2.1e-06 27.8 0.0 4.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GBG79965.1 - 0.00027 20.8 0.0 0.00073 19.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GBG79965.1 - 0.037 13.7 0.1 0.57 9.9 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 GBG79965.1 - 0.059 13.1 0.9 0.41 10.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GBG79965.1 - 0.18 12.3 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) rve PF00665.26 GBG79966.1 - 1e-14 54.8 0.0 2.7e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain MCM_lid PF17855.1 GBG79966.1 - 1.7e-14 54.0 0.0 5.3e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_lid_2 PF17863.1 GBG79966.1 - 0.0075 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain Poxvirus PF06227.12 GBG79966.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 dsDNA Poxvirus DUF1564 PF07600.11 GBG79966.1 - 0.03 14.0 0.4 0.15 11.7 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) B56 PF01603.20 GBG79968.1 - 1.7e-193 643.3 4.2 2e-193 643.0 4.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sporozoite_P67 PF05642.11 GBG79968.1 - 0.12 10.5 4.4 0.15 10.2 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dec-1 PF04624.14 GBG79968.1 - 0.25 11.2 0.5 0.45 10.4 0.5 1.3 1 0 0 1 1 1 0 Dec-1 repeat RVT_1 PF00078.27 GBG79969.1 - 6e-30 104.4 0.0 9.6e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CSRNP_N PF16019.5 GBG79969.1 - 1 9.2 3.7 1.8 8.4 3.7 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus gag-asp_proteas PF13975.6 GBG79970.1 - 2.6e-07 31.1 0.5 1.1e-06 29.1 0.1 2.3 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG79970.1 - 3e-05 24.6 0.1 9.6e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG79970.1 - 0.00049 19.9 0.2 0.00094 19.0 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG79970.1 - 0.0037 17.0 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease cNMP_binding PF00027.29 GBG79970.1 - 0.055 13.5 0.0 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain LEA_5 PF00477.17 GBG79971.1 - 5.2e-27 94.5 48.0 1.7e-24 86.4 17.8 2.9 1 1 1 2 2 2 2 Small hydrophilic plant seed protein KGG PF10685.9 GBG79971.1 - 3 8.2 48.9 0.088 13.1 4.6 6.7 7 0 0 7 7 7 0 Stress-induced bacterial acidophilic repeat motif Mod_r PF07200.13 GBG79972.1 - 1.1e-31 110.0 12.9 1.3e-31 109.6 12.9 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 GBG79972.1 - 0.2 12.2 17.8 6.4 7.3 17.8 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region MRP-S26 PF14943.6 GBG79972.1 - 0.56 10.1 8.7 0.72 9.8 8.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PhoU PF01895.19 GBG79972.1 - 0.77 10.3 6.3 0.63 10.5 0.6 2.9 2 1 1 3 3 3 0 PhoU domain COX5B PF01215.19 GBG79974.1 - 3.7e-19 68.7 0.1 5.2e-19 68.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 GBG79974.1 - 8.6e-07 28.9 0.2 1.4e-06 28.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain Coronavirus_5 PF05528.11 GBG79974.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Coronavirus gene 5 protein Zn-C2H2_12 PF18112.1 GBG79974.1 - 0.12 12.9 0.5 0.22 12.0 0.5 1.4 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain LEA_5 PF00477.17 GBG79975.1 - 2.1e-20 73.2 6.1 2.1e-20 73.2 6.1 2.0 2 1 0 2 2 2 1 Small hydrophilic plant seed protein PPDK_N PF01326.19 GBG79977.1 - 8.7e-27 94.2 0.0 7.2e-26 91.2 0.0 2.1 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM_20 PF00686.19 GBG79977.1 - 2.4e-13 49.8 0.1 9.6e-13 47.9 0.1 2.0 2 0 0 2 2 2 1 Starch binding domain PPDK_N PF01326.19 GBG79978.1 - 8.7e-27 94.2 0.0 7.2e-26 91.2 0.0 2.1 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM_20 PF00686.19 GBG79978.1 - 2.4e-13 49.8 0.1 9.6e-13 47.9 0.1 2.0 2 0 0 2 2 2 1 Starch binding domain RVT_1 PF00078.27 GBG79979.1 - 4.5e-28 98.3 0.1 8.5e-28 97.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG79979.1 - 2.8e-15 56.1 0.9 9.2e-15 54.5 0.1 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG79979.1 - 7.7e-07 29.3 0.0 4.3e-06 26.9 0.0 2.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG79979.1 - 2.3e-05 24.5 0.0 6.7e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger BNR_2 PF13088.6 GBG79980.1 - 3.5e-40 138.1 0.9 6.4e-40 137.2 0.9 1.4 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 GBG79980.1 - 0.0022 17.7 23.6 0.51 10.6 2.1 5.7 5 0 0 5 5 5 3 BNR/Asp-box repeat FYVE PF01363.21 GBG79981.1 - 2.9e-19 68.9 12.8 2.9e-19 68.9 12.8 3.1 3 0 0 3 3 3 2 FYVE zinc finger Elf1 PF05129.13 GBG79981.1 - 1.2 9.2 15.2 3.8 7.6 0.1 3.6 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.7 GBG79981.1 - 4.1 7.5 27.3 0.3 11.1 0.6 4.4 3 1 0 3 3 3 0 Double zinc ribbon Keratin_assoc PF09775.9 GBG79982.1 - 0.0092 15.6 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 DapB_N PF01113.20 GBG79983.1 - 5.5e-17 62.1 0.4 1e-16 61.2 0.4 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DapB_C PF05173.14 GBG79983.1 - 3.5e-10 39.9 0.0 8e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus Aminotran_1_2 PF00155.21 GBG79985.1 - 1.6e-66 224.9 0.0 2.1e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GBG79985.1 - 3.4e-08 33.2 0.0 5.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 GBG79985.1 - 9.9e-08 31.3 0.0 1.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GBG79985.1 - 3.3e-07 29.2 0.0 4.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 GBG79985.1 - 2.2e-05 23.9 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase WD40 PF00400.32 GBG79986.1 - 2.1e-10 41.0 4.3 0.1 13.5 0.0 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat GCIP PF13324.6 GBG79986.1 - 0.0062 16.2 0.6 0.011 15.4 0.6 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting ANAPC4_WD40 PF12894.7 GBG79986.1 - 0.063 13.6 0.0 12 6.2 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BRK PF07533.16 GBG79986.1 - 0.086 12.5 0.4 6.6 6.4 0.0 2.9 2 0 0 2 2 2 0 BRK domain FAM176 PF14851.6 GBG79986.1 - 0.15 11.7 0.1 0.53 9.9 0.1 2.0 1 0 0 1 1 1 0 FAM176 family DUF2615 PF11027.8 GBG79986.1 - 0.68 10.1 2.9 0.65 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) NOA36 PF06524.12 GBG79986.1 - 10 5.4 11.5 22 4.3 11.5 1.5 1 0 0 1 1 1 0 NOA36 protein SRP14 PF02290.15 GBG79987.1 - 2.5e-22 79.0 0.1 3.3e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DNA_pol3_alpha PF07733.12 GBG79988.1 - 7.7e-89 297.7 0.0 1.3e-88 296.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 GBG79988.1 - 2.5e-55 186.3 0.0 4.2e-55 185.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 GBG79988.1 - 8.4e-44 149.8 0.0 1.7e-43 148.8 0.0 1.6 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 GBG79988.1 - 1e-24 86.6 0.0 2.8e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 GBG79988.1 - 1.7e-06 27.9 0.3 4.2e-06 26.7 0.3 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 GBG79988.1 - 0.1 12.6 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) SAPS PF04499.15 GBG79989.1 - 0.56 8.9 11.4 0.65 8.7 11.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PG_binding_1 PF01471.18 GBG79990.1 - 5.1e-08 33.0 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain DnaJ_CXXCXGXG PF00684.19 GBG79990.1 - 9e-06 26.0 8.3 5.5e-05 23.4 8.3 2.3 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GBG79990.1 - 0.23 11.5 10.5 0.14 12.1 0.9 3.4 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DDRGK PF09756.9 GBG79990.1 - 0.72 9.4 8.5 1.2 8.7 8.5 1.3 1 0 0 1 1 1 0 DDRGK domain DUF1356 PF07092.12 GBG79990.1 - 0.87 8.8 4.7 1.1 8.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) FUSC PF04632.12 GBG79990.1 - 5.9 5.3 7.0 8.4 4.8 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ETC_C1_NDUFA4 PF04800.12 GBG79991.1 - 3e-34 117.1 0.9 4.1e-34 116.7 0.9 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region AA_permease_2 PF13520.6 GBG79992.1 - 4.6e-38 131.2 31.4 5.7e-38 130.9 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GBG79992.1 - 4.8e-16 58.4 27.2 7.1e-15 54.6 27.2 2.0 1 1 0 1 1 1 1 Amino acid permease TFIID_30kDa PF03540.13 GBG79993.1 - 8.9e-19 67.2 0.0 1.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 GBG79993.1 - 0.1 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PNRC PF15365.6 GBG79994.1 - 0.025 14.4 1.0 0.045 13.6 1.0 1.5 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif RVT_1 PF00078.27 GBG79995.1 - 3.6e-28 98.6 0.1 5.6e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG79995.1 - 1.2e-12 47.9 0.2 2.6e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG79995.1 - 0.022 14.5 0.6 0.069 12.9 0.2 2.2 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region zf-CCHC_6 PF15288.6 GBG79996.1 - 0.2 11.5 3.5 0.6 10.0 3.5 1.8 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG79997.1 - 5.2e-26 91.0 0.0 1.2e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG79997.1 - 6e-26 90.4 0.0 9.8e-26 89.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG79997.1 - 0.3 9.3 10.4 0.39 8.9 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG79997.1 - 1.5 7.1 10.9 2.1 6.5 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG79997.1 - 2.1 7.7 11.3 3 7.2 11.3 1.2 1 0 0 1 1 1 0 SDA1 Retrotrans_gag PF03732.17 GBG79998.1 - 0.0068 16.7 0.2 0.0068 16.7 0.2 3.2 4 1 0 4 4 4 1 Retrotransposon gag protein FAM76 PF16046.5 GBG79998.1 - 0.029 13.8 8.1 0.042 13.2 8.1 1.2 1 0 0 1 1 1 0 FAM76 protein TAF4 PF05236.14 GBG79998.1 - 0.041 13.6 8.2 0.12 12.1 8.3 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family SoPB_HTH PF18090.1 GBG79998.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Centromere-binding protein HTH domain UPF0242 PF06785.11 GBG79998.1 - 3.9 7.5 16.2 34 4.4 16.2 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PspB PF06667.12 GBG79998.1 - 6.7 6.8 10.6 12 6.0 0.2 3.1 3 0 0 3 3 3 0 Phage shock protein B Pkinase PF00069.25 GBG80001.1 - 2.1e-31 109.2 0.0 3.2e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG80001.1 - 8.8e-31 107.1 0.0 1.4e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L35Ae PF01247.18 GBG80002.1 - 1.2e-11 44.6 0.2 1.3e-11 44.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae Pkinase_Tyr PF07714.17 GBG80004.1 - 1.4e-29 103.2 0.0 4.7e-29 101.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG80004.1 - 1.4e-27 96.7 0.0 2.1e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain MgtE_N PF03448.17 GBG80004.1 - 0.028 15.0 7.9 0.051 14.2 7.9 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain Gag_p24 PF00607.20 GBG80005.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Myb_DNA-bind_4 PF13837.6 GBG80007.1 - 2.2e-05 24.8 0.8 3.9e-05 24.0 0.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Integrase_H2C2 PF17921.1 GBG80008.1 - 2e-15 56.6 0.1 4.4e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80008.1 - 2.1e-14 53.7 0.0 4.9e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80008.1 - 0.0029 17.8 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG80010.1 - 5.1e-29 100.3 0.0 9.1e-29 99.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80010.1 - 5.8e-27 94.0 0.0 1.2e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80010.1 - 6.3e-16 58.2 0.1 1.8e-15 56.8 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80010.1 - 3.6e-15 56.2 0.1 1.9e-14 53.9 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain U1snRNP70_N PF12220.8 GBG80010.1 - 0.038 14.6 0.2 0.11 13.2 0.2 1.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-H2C2 PF09337.10 GBG80010.1 - 0.052 13.8 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Mcp5_PH PF12814.7 GBG80010.1 - 0.14 12.2 2.3 0.1 12.7 0.4 1.7 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Mpp10 PF04006.12 GBG80011.1 - 0.0027 16.2 10.5 0.0027 16.2 10.5 2.1 2 0 0 2 2 2 1 Mpp10 protein Retrotrans_gag PF03732.17 GBG80011.1 - 0.01 16.1 2.0 0.035 14.4 0.0 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein DUF4407 PF14362.6 GBG80011.1 - 0.66 9.3 7.0 1.5 8.1 5.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RNase_H2_suC PF08615.11 GBG80011.1 - 9.1 6.5 8.8 42 4.3 5.6 3.0 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) NPV_P10 PF05531.12 GBG80012.1 - 1.7 9.1 4.2 6.9 7.2 0.4 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 GBG80012.1 - 1.8 8.9 11.1 0.3 11.4 1.8 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.11 GBG80012.1 - 2.3 8.5 11.2 2.6 8.4 2.2 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 RVT_1 PF00078.27 GBG80013.1 - 3.7e-28 98.6 0.1 5.5e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80013.1 - 0.013 16.2 0.0 0.027 15.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease UQ_con PF00179.26 GBG80014.1 - 3.2e-54 182.4 0.0 3.6e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GBG80014.1 - 0.00081 19.7 0.0 0.00096 19.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 GBG80014.1 - 0.017 14.9 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 GBG80014.1 - 0.036 13.9 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain Dimer_Tnp_hAT PF05699.14 GBG80015.1 - 8e-09 35.2 3.1 9.2e-09 35.0 1.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG80016.1 - 3.3e-31 108.5 0.0 4.9e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80016.1 - 6.6e-21 74.2 0.0 1.7e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80016.1 - 3.6e-11 43.3 0.0 8.8e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG80016.1 - 2.2e-09 37.6 0.0 6e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3552 PF12072.8 GBG80019.1 - 0.027 13.9 0.0 0.034 13.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Syntaxin-6_N PF09177.11 GBG80019.1 - 0.043 14.4 0.0 0.058 14.0 0.0 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF1465 PF07323.12 GBG80019.1 - 0.047 13.5 0.1 0.06 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) IL15 PF02372.15 GBG80020.1 - 0.08 13.0 2.6 18 5.3 1.1 3.2 3 0 0 3 3 3 0 Interleukin 15 DAGK_cat PF00781.24 GBG80021.1 - 1.4e-33 115.2 0.9 1.8e-32 111.6 0.0 2.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain DUF659 PF04937.15 GBG80021.1 - 3.3e-15 56.3 0.0 5.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80021.1 - 3.2e-09 36.5 0.2 7.2e-09 35.3 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3701 PF12482.8 GBG80021.1 - 0.094 12.8 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 Phage integrase protein Presenilin PF01080.17 GBG80021.1 - 0.35 9.6 0.9 0.51 9.0 0.9 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 GBG80021.1 - 2.6 6.5 6.9 4 5.9 6.9 1.2 1 0 0 1 1 1 0 Macoilin family Fis1_TPR_C PF14853.6 GBG80022.1 - 1.4e-17 63.5 0.0 2e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 GBG80022.1 - 4.3e-08 32.7 0.1 5.3e-06 26.1 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 GBG80022.1 - 4.5e-07 29.4 0.0 8.5e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_14 PF13428.6 GBG80022.1 - 3.5e-06 27.4 1.4 8e-05 23.1 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG80022.1 - 0.00073 19.8 1.3 0.0036 17.6 1.3 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG80022.1 - 0.0018 18.0 0.0 0.0086 15.9 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG80022.1 - 0.0018 18.1 1.2 0.012 15.6 0.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GBG80022.1 - 0.0025 18.3 3.2 0.062 14.0 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG80022.1 - 0.0046 16.8 2.5 0.013 15.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG80022.1 - 0.0084 16.6 1.5 0.072 13.6 0.2 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG80022.1 - 0.038 14.2 0.1 0.12 12.6 0.1 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GBG80022.1 - 0.048 13.9 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 GBG80022.1 - 0.051 13.3 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.6 GBG80022.1 - 0.1 13.3 7.2 0.23 12.1 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG80022.1 - 0.44 10.7 0.1 0.44 10.7 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 GBG80022.1 - 0.79 10.5 0.1 0.79 10.5 0.1 3.7 4 1 1 5 5 4 0 Tetratricopeptide repeat BORCS8 PF10167.9 GBG80023.1 - 4.1e-21 75.0 0.0 8.2e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 RT_RNaseH_2 PF17919.1 GBG80026.1 - 6.9e-34 115.9 0.0 1.7e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80026.1 - 1.8e-29 102.1 0.4 5.4e-29 100.6 0.0 2.1 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80026.1 - 7.2e-25 87.8 0.0 1.3e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80026.1 - 2.8e-08 33.6 0.0 5.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80026.1 - 0.022 15.4 0.0 0.061 14.0 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG80026.1 - 0.025 14.8 0.3 0.29 11.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG80026.1 - 0.066 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Snapin_Pallidin PF14712.6 GBG80026.1 - 0.23 11.9 6.4 1.3 9.5 0.0 3.1 2 0 0 2 2 2 0 Snapin/Pallidin EzrA PF06160.12 GBG80026.1 - 0.64 8.1 6.8 1.3 7.2 6.8 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4140 PF13600.6 GBG80026.1 - 2.7 8.5 5.5 55 4.3 1.1 3.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Phage_GPO PF05929.11 GBG80026.1 - 10 5.7 8.3 3.1 7.4 0.0 2.6 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RVP_2 PF08284.11 GBG80027.1 - 1.3e-05 24.9 0.0 0.00011 21.9 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80027.1 - 0.00058 20.5 0.0 0.0013 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80027.1 - 0.00073 20.0 0.0 0.002 18.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80027.1 - 0.012 15.4 0.0 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease YwqJ-deaminase PF14431.6 GBG80027.1 - 0.019 15.2 0.7 0.041 14.1 0.3 1.8 1 1 0 1 1 1 0 YwqJ-like deaminase SlyX PF04102.12 GBG80027.1 - 0.069 13.8 0.0 0.069 13.8 0.0 3.4 3 0 0 3 3 3 0 SlyX DDRGK PF09756.9 GBG80027.1 - 2.4 7.7 8.8 4 7.0 8.8 1.2 1 0 0 1 1 1 0 DDRGK domain RT_RNaseH_2 PF17919.1 GBG80028.1 - 3.4e-31 107.2 0.0 1.5e-30 105.2 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80028.1 - 1.4e-30 105.6 0.1 5e-30 103.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG80028.1 - 0.13 11.9 4.1 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG80029.1 - 7.1e-32 109.4 0.0 1.4e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80029.1 - 1.5e-27 95.9 0.0 2.8e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80029.1 - 8.5e-17 61.4 0.0 2e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG80029.1 - 8.1e-16 57.9 0.6 1.5e-14 53.8 0.1 3.0 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG80029.1 - 0.0013 18.9 0.0 0.0038 17.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG80029.1 - 0.0025 17.3 0.1 0.0049 16.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) eIF-1a PF01176.19 GBG80029.1 - 0.039 13.8 0.1 0.083 12.7 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Rhamno_transf PF11316.8 GBG80029.1 - 0.05 13.0 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase rve_3 PF13683.6 GBG80029.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain MREG PF15812.5 GBG80030.1 - 0.44 10.8 8.5 1.6 9.1 6.2 2.3 1 1 1 2 2 2 0 Melanoregulin Pkinase_Tyr PF07714.17 GBG80031.1 - 1.4e-27 96.6 0.0 1.6e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG80031.1 - 2.4e-27 95.9 0.0 2.6e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG80031.1 - 0.00019 20.4 0.0 0.00024 20.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG80031.1 - 0.0041 17.1 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GBG80031.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RVP_2 PF08284.11 GBG80032.1 - 4.1e-07 29.8 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80032.1 - 0.00014 22.4 0.0 0.00036 21.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80032.1 - 0.00032 21.2 0.0 0.001 19.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SlyX PF04102.12 GBG80032.1 - 0.015 15.9 0.3 0.015 15.9 0.3 3.1 3 0 0 3 3 3 0 SlyX 4HBT_3 PF13622.6 GBG80032.1 - 0.05 13.9 0.9 2.2 8.5 0.0 2.8 2 1 1 3 3 3 0 Thioesterase-like superfamily GPR15L PF15854.5 GBG80034.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Herpes_gE PF02480.16 GBG80034.1 - 0.031 13.0 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NCU-G1 PF15065.6 GBG80034.1 - 2.1 7.2 0.0 2.1 7.2 0.0 2.0 1 1 1 2 2 2 0 Lysosomal transcription factor, NCU-G1 rve PF00665.26 GBG80035.1 - 3e-09 37.1 0.1 4.9e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain PUF PF00806.19 GBG80035.1 - 0.21 11.3 0.5 0.83 9.5 0.0 2.1 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat PRTP PF01366.18 GBG80036.1 - 0.52 8.3 6.5 0.62 8.0 6.5 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Herpes_UL25 PF01499.16 GBG80036.1 - 9.8 4.6 14.1 0.25 9.8 8.1 1.3 2 0 0 2 2 2 0 Herpesvirus UL25 family Sigma70_r4 PF04545.16 GBG80037.1 - 0.043 13.3 0.0 1.5 8.4 0.0 2.6 3 0 0 3 3 3 0 Sigma-70, region 4 RT_RNaseH_2 PF17919.1 GBG80039.1 - 5.9e-31 106.5 0.0 1.2e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80039.1 - 3.7e-29 101.1 0.1 9.7e-29 99.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80039.1 - 4.4e-19 68.4 0.3 9.2e-19 67.3 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80039.1 - 3.9e-12 46.2 0.2 8.1e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG80039.1 - 0.0011 19.1 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger MnmE_helical PF12631.7 GBG80039.1 - 0.38 10.9 1.9 1.7 8.8 0.0 2.5 3 0 0 3 3 3 0 MnmE helical domain TMF_TATA_bd PF12325.8 GBG80041.1 - 0.59 10.4 4.6 0.92 9.7 0.2 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding RBD-FIP PF09457.10 GBG80041.1 - 1.5 8.8 8.2 0.32 10.9 1.3 3.0 3 0 0 3 3 3 0 FIP domain Kelch_4 PF13418.6 GBG80042.1 - 1.6e-40 136.8 13.8 4.5e-08 33.0 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GBG80042.1 - 7.3e-38 128.2 22.5 3.5e-10 39.9 0.1 8.3 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG80042.1 - 6.5e-29 99.4 8.6 7.3e-05 22.7 0.0 7.2 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 GBG80042.1 - 1.3e-27 95.1 14.4 2.3e-05 24.5 0.2 6.6 4 1 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GBG80042.1 - 1.7e-25 88.3 15.7 2.4e-07 30.2 0.0 6.5 6 1 1 7 7 7 5 Kelch motif Kelch_2 PF07646.15 GBG80042.1 - 1.2e-22 79.0 12.1 0.00074 19.4 0.2 6.9 6 0 0 6 6 6 5 Kelch motif DUF659 PF04937.15 GBG80042.1 - 6.6e-20 71.5 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80042.1 - 0.00014 21.6 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RAG2 PF03089.14 GBG80042.1 - 0.24 10.3 0.1 3.8 6.4 0.0 2.8 3 1 0 3 3 3 0 Recombination activating protein 2 Kelch_4 PF13418.6 GBG80043.1 - 5.2e-42 141.6 14.0 5.1e-08 32.8 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GBG80043.1 - 3.4e-38 129.2 22.5 3.9e-10 39.8 0.1 8.2 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG80043.1 - 8.8e-29 99.0 8.6 8.1e-05 22.5 0.0 7.2 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 GBG80043.1 - 8.7e-28 95.7 14.6 2.6e-05 24.4 0.2 6.6 4 1 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GBG80043.1 - 3.6e-25 87.3 15.9 2.7e-07 30.1 0.0 6.4 6 1 1 7 7 7 5 Kelch motif Kelch_2 PF07646.15 GBG80043.1 - 4.5e-22 77.1 12.4 0.00082 19.2 0.2 6.9 6 0 0 6 6 6 5 Kelch motif DUF659 PF04937.15 GBG80043.1 - 7.2e-20 71.4 0.0 1.3e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80043.1 - 0.00013 21.6 0.0 0.00039 20.2 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RAG2 PF03089.14 GBG80043.1 - 0.091 11.7 0.0 4.2 6.3 0.0 2.9 3 1 0 3 3 3 0 Recombination activating protein 2 DUF4611 PF15387.6 GBG80043.1 - 1.6 9.0 6.9 0.46 10.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Kelch_4 PF13418.6 GBG80044.1 - 3.3e-40 135.9 13.8 5.1e-08 32.8 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GBG80044.1 - 1.7e-37 127.0 22.5 3.9e-10 39.8 0.1 8.2 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG80044.1 - 1.2e-28 98.5 8.6 8.1e-05 22.5 0.0 7.2 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 GBG80044.1 - 2.4e-27 94.3 14.4 2.6e-05 24.3 0.2 6.6 4 1 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GBG80044.1 - 2.8e-25 87.6 15.6 2.7e-07 30.1 0.0 6.4 6 1 1 7 7 7 5 Kelch motif Kelch_2 PF07646.15 GBG80044.1 - 2.3e-22 78.1 12.1 0.00083 19.2 0.2 6.9 6 0 0 6 6 6 5 Kelch motif DUF659 PF04937.15 GBG80044.1 - 7.2e-20 71.4 0.0 1.3e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80044.1 - 0.00013 21.6 0.0 0.00039 20.2 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4611 PF15387.6 GBG80044.1 - 1.6 9.0 6.9 0.46 10.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Kelch_4 PF13418.6 GBG80045.1 - 3.3e-40 135.8 13.8 5.1e-08 32.8 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GBG80045.1 - 1.7e-37 127.0 22.5 3.9e-10 39.8 0.1 8.2 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG80045.1 - 1.2e-28 98.5 8.6 8.1e-05 22.5 0.0 7.2 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 GBG80045.1 - 2.4e-27 94.2 14.4 2.6e-05 24.3 0.2 6.6 4 1 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GBG80045.1 - 2.9e-25 87.6 15.6 2.7e-07 30.1 0.0 6.4 6 1 1 7 7 7 5 Kelch motif Kelch_2 PF07646.15 GBG80045.1 - 2.3e-22 78.0 12.1 0.00083 19.2 0.2 6.9 6 0 0 6 6 6 5 Kelch motif DUF659 PF04937.15 GBG80045.1 - 7.2e-20 71.4 0.0 1.3e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80045.1 - 0.00013 21.6 0.0 0.00039 20.2 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4611 PF15387.6 GBG80045.1 - 1.6 9.0 6.9 0.46 10.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Integrase_H2C2 PF17921.1 GBG80046.1 - 1.2e-14 54.2 0.0 2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80046.1 - 4.1e-05 23.8 0.1 0.00033 20.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG80046.1 - 0.0059 16.8 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG80047.1 - 9.8e-06 26.1 0.0 4.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80047.1 - 2e-05 25.1 0.0 8.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG80047.1 - 4.6e-05 23.2 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG80047.1 - 8.4e-05 22.8 1.8 0.0009 19.5 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG80047.1 - 0.0015 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease HIP1_clath_bdg PF16515.5 GBG80047.1 - 0.013 16.1 4.3 0.013 16.1 4.3 2.9 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Senescence_reg PF04520.13 GBG80047.1 - 0.046 14.6 4.0 0.068 14.0 1.1 2.7 3 0 0 3 3 3 0 Senescence regulator Exonuc_VII_L PF02601.15 GBG80047.1 - 6.7 6.2 8.8 11 5.4 8.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Chromo PF00385.24 GBG80048.1 - 0.00013 21.8 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CDH1_2_SANT_HL1 PF18375.1 GBG80048.1 - 0.23 12.2 0.7 1.8 9.3 0.0 2.6 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 DUF3801 PF12687.7 GBG80048.1 - 1.4 9.0 8.3 4 7.5 8.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) TFIIA PF03153.13 GBG80048.1 - 5.1 7.0 14.7 3.5 7.5 13.0 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF416 PF04222.12 GBG80050.1 - 0.05 13.0 2.0 0.12 11.8 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF416) FAM199X PF15814.5 GBG80050.1 - 1.2 8.1 10.9 1.9 7.5 10.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X Vac_ImportDeg PF09783.9 GBG80051.1 - 8.9e-50 168.7 0.1 1e-49 168.5 0.1 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF4172 PF13776.6 GBG80051.1 - 0.098 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) IL3Ra_N PF18611.1 GBG80052.1 - 0.027 14.4 0.1 0.062 13.3 0.1 1.6 1 0 0 1 1 1 0 IL-3 receptor alpha chain N-terminal domain Mac PF12464.8 GBG80052.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Maltose acetyltransferase FGGY_C PF02782.16 GBG80053.1 - 6.3e-62 208.8 0.0 1.6e-61 207.5 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GBG80053.1 - 4.7e-59 199.9 0.2 2.5e-41 141.9 0.1 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain RT_RNaseH_2 PF17919.1 GBG80053.1 - 9.7e-32 109.0 0.0 2.3e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80053.1 - 1.4e-30 105.7 0.3 3.7e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80053.1 - 4.2e-07 29.7 0.1 6.9e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80054.1 - 6.8e-09 35.6 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80054.1 - 6.8e-05 22.7 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG80054.1 - 9.3e-05 23.0 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80054.1 - 0.00014 22.3 0.0 0.00035 21.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease eIF-1a PF01176.19 GBG80054.1 - 0.046 13.5 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 Integrase_H2C2 PF17921.1 GBG80056.1 - 5.4e-15 55.2 0.2 1.1e-14 54.2 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80056.1 - 8.3e-15 55.0 0.0 2.1e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80056.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG80056.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG80057.1 - 4.4e-30 103.7 0.0 8.9e-30 102.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80057.1 - 1.9e-27 95.6 0.0 3.9e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Band_7 PF01145.25 GBG80057.1 - 2.4e-21 76.5 0.1 2.4e-21 76.5 0.1 2.7 3 0 0 3 3 3 1 SPFH domain / Band 7 family Integrase_H2C2 PF17921.1 GBG80057.1 - 1.8e-10 40.8 0.0 5.2e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80057.1 - 0.015 14.8 0.2 0.08 12.4 0.1 2.2 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG80057.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG80059.1 - 4.8e-35 121.1 0.1 8e-35 120.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80059.1 - 1.7e-17 63.3 0.0 1.9e-16 59.9 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80059.1 - 3e-07 30.7 0.0 9e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Caldesmon PF02029.15 GBG80059.1 - 2.4 6.8 81.1 0.27 9.9 23.1 2.3 2 0 0 2 2 2 0 Caldesmon BSP_II PF05432.11 GBG80060.1 - 0.06 13.0 9.3 0.073 12.8 9.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SURF2 PF05477.11 GBG80060.1 - 0.09 12.5 9.9 0.12 12.0 9.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC27 PF09507.10 GBG80060.1 - 0.94 8.8 12.9 1.3 8.3 12.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nucleo_P87 PF07267.11 GBG80060.1 - 3.5 6.4 6.0 5.6 5.7 6.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 GBG80060.1 - 4.4 6.0 4.7 5.1 5.7 4.7 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 GBG80060.1 - 7.3 4.5 11.4 9 4.3 11.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 GBG80060.1 - 7.8 6.4 15.6 55 3.6 15.6 1.9 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RVT_1 PF00078.27 GBG80061.1 - 3.9e-34 118.1 0.0 6.5e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80061.1 - 6.6e-25 87.4 0.0 1.6e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80061.1 - 1.1e-24 86.4 0.0 3.1e-24 84.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80061.1 - 4.6e-13 49.1 0.1 9.9e-13 48.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80061.1 - 5.4e-09 36.3 0.0 1.4e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG80061.1 - 2.6e-06 27.2 0.0 9.1e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80061.1 - 9e-06 26.3 0.0 2.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80061.1 - 0.0013 19.2 0.0 0.012 16.1 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG80061.1 - 0.016 15.0 0.0 0.051 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative peptidase (DUF1758) T4_baseplate PF12322.8 GBG80061.1 - 0.017 14.6 2.8 0.034 13.6 2.8 1.4 1 0 0 1 1 1 0 T4 bacteriophage base plate protein DUF4632 PF15451.6 GBG80061.1 - 0.054 13.6 0.3 0.18 11.9 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) RT_RNaseH_2 PF17919.1 GBG80064.1 - 2.4e-17 62.8 0.0 5.1e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80064.1 - 6.4e-07 29.6 0.0 1.8e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80064.1 - 2.6e-05 23.9 0.2 5.8e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80065.1 - 1.1e-30 105.7 0.0 9.4e-16 57.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80065.1 - 1.5e-27 96.0 0.0 4.5e-27 94.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80065.1 - 5.4e-24 84.9 0.1 1e-23 84.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3824 PF12868.7 GBG80065.1 - 7.1 7.3 9.9 16 6.1 9.9 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) RT_RNaseH_2 PF17919.1 GBG80067.1 - 1e-32 112.1 0.1 2.8e-32 110.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80067.1 - 1.4e-30 105.7 0.1 3e-30 104.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80067.1 - 6.2e-19 67.9 0.2 1.6e-18 66.5 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80067.1 - 1.9e-14 53.9 0.0 6.7e-14 52.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG80067.1 - 1.9e-11 43.9 0.2 3.5e-11 43.0 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG80067.1 - 0.013 15.2 0.0 0.049 13.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG80068.1 - 3e-25 89.1 0.0 4.1e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80068.1 - 1.7e-11 44.0 0.0 3.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80068.1 - 0.00089 19.5 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80070.1 - 3.3e-24 85.6 3.1 1.2e-23 83.8 0.2 2.5 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80070.1 - 4.5e-16 58.7 0.2 9.1e-16 57.7 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG80070.1 - 4.4e-14 52.6 0.0 1.3e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG80070.1 - 9.7e-07 28.6 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG80070.1 - 3e-06 27.2 0.0 9.6e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG80070.1 - 7.8e-06 26.4 0.0 3.1e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80070.1 - 9.9e-05 22.8 0.0 0.00036 21.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80070.1 - 0.0081 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG80070.1 - 0.013 16.2 2.9 0.1 13.2 0.6 3.3 3 0 0 3 3 3 0 SlyX WTX PF09422.10 GBG80070.1 - 0.22 10.6 2.3 0.38 9.8 2.3 1.3 1 0 0 1 1 1 0 WTX protein RT_RNaseH_2 PF17919.1 GBG80071.1 - 1.9e-56 188.3 0.0 1.2e-32 112.0 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80071.1 - 5.5e-42 142.3 0.2 2.5e-29 101.6 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80071.1 - 2.7e-29 102.3 0.0 5.1e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG80071.1 - 2.8e-05 24.6 0.0 6.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80071.1 - 0.00017 22.2 0.0 0.00037 21.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG80071.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG80071.1 - 0.022 14.6 0.1 0.056 13.2 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG80071.1 - 0.029 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease TcdB_N PF12918.7 GBG80071.1 - 0.049 13.9 0.4 9.7 6.6 0.0 3.1 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain DUF5095 PF17016.5 GBG80071.1 - 0.13 11.9 1.7 0.91 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) SlyX PF04102.12 GBG80072.1 - 0.0003 21.3 1.2 0.0003 21.3 1.2 3.0 2 1 1 3 3 3 1 SlyX TolA_bind_tri PF16331.5 GBG80072.1 - 0.038 14.1 2.3 0.038 14.1 2.3 3.2 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF1664 PF07889.12 GBG80072.1 - 0.048 13.7 1.1 0.12 12.5 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 GBG80072.1 - 0.13 10.9 7.2 0.24 10.0 7.3 1.4 1 1 0 1 1 1 0 AAA domain ATG16 PF08614.11 GBG80072.1 - 0.17 12.1 10.9 0.27 11.4 10.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 GBG80072.1 - 2.9 7.1 4.0 0.73 9.0 0.3 1.7 2 0 0 2 2 2 0 TMPIT-like protein MIF4G_like_2 PF09090.11 GBG80072.1 - 6.8 6.1 8.3 2 7.8 0.1 2.0 1 1 1 2 2 2 0 MIF4G like RVT_1 PF00078.27 GBG80073.1 - 3.3e-28 98.7 0.0 5.7e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG80073.1 - 3.1e-06 27.7 0.0 9.2e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80073.1 - 0.00016 22.3 0.0 0.00059 20.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease DUF1564 PF07600.11 GBG80073.1 - 0.0017 18.0 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) Asp_protease PF09668.10 GBG80073.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease HepII_C PF18675.1 GBG80073.1 - 0.14 12.3 0.0 25 5.0 0.0 2.6 2 0 0 2 2 2 0 Heparinase II C-terminal domain DUF1758 PF05585.12 GBG80073.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Nop53 PF07767.11 GBG80074.1 - 0.93 8.8 48.8 1.1 8.5 48.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GBG80074.1 - 2 6.6 36.8 2.4 6.4 36.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG80074.1 - 2.9 6.0 35.2 3.3 5.8 35.2 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG80075.1 - 3.8e-55 186.8 0.1 1.2e-26 93.6 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80075.1 - 2.1e-15 56.6 0.0 7.2e-15 54.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80075.1 - 1.3e-06 28.7 0.0 3.9e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG80075.1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80075.1 - 0.00065 20.3 0.0 0.0019 18.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80075.1 - 0.00076 20.0 0.0 0.0024 18.4 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG80075.1 - 0.0015 18.7 1.3 0.26 11.6 0.0 4.1 3 0 0 3 3 3 1 Retrotransposon gag protein Trans_reg_C PF00486.28 GBG80075.1 - 0.0053 16.8 0.7 5.3 7.2 0.1 3.2 3 0 0 3 3 3 2 Transcriptional regulatory protein, C terminal Asp_protease PF09668.10 GBG80075.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Fib_alpha PF08702.10 GBG80075.1 - 1.3 9.2 4.8 1.8 8.8 0.2 3.1 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Integrase_H2C2 PF17921.1 GBG80076.1 - 6e-10 39.1 1.7 6.9e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG80076.1 - 1.7e-06 28.3 0.1 4.2e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG80077.1 - 4.1e-08 33.8 0.0 9.7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80077.1 - 3e-07 30.9 0.0 6.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80077.1 - 4.9e-06 26.3 0.0 8.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80077.1 - 9.6e-05 22.2 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG80077.1 - 0.0017 17.9 0.1 0.0032 17.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 GBG80077.1 - 3.7 6.2 14.1 7.2 5.3 14.1 1.4 1 0 0 1 1 1 0 Presenilin Dicty_REP PF05086.12 GBG80077.1 - 6.1 4.7 6.7 9.3 4.1 6.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RVT_1 PF00078.27 GBG80078.1 - 1.6e-32 112.8 0.1 2.6e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80078.1 - 4.1e-15 56.0 0.0 9e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG80078.1 - 1.3e-14 54.1 0.1 8.7e-14 51.4 0.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG80078.1 - 0.0042 17.3 0.0 0.016 15.4 0.0 2.0 2 0 0 2 2 2 1 H2C2 zinc finger CCDC85 PF10226.9 GBG80078.1 - 0.051 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 CCDC85 family DUF3417 PF11897.8 GBG80078.1 - 0.061 13.8 0.0 0.26 11.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF2385 PF09539.10 GBG80078.1 - 0.093 13.3 0.2 1.3 9.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) HALZ PF02183.18 GBG80078.1 - 0.1 12.8 1.4 0.49 10.7 1.4 2.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper YscO PF07321.12 GBG80078.1 - 0.4 10.6 11.1 1.2 9.1 11.1 1.8 1 0 0 1 1 1 0 Type III secretion protein YscO bZIP_2 PF07716.15 GBG80078.1 - 1.8 8.7 13.4 0.093 12.8 2.9 3.0 3 0 0 3 3 3 0 Basic region leucine zipper RVT_1 PF00078.27 GBG80079.1 - 4.7e-29 101.5 0.3 4.2e-28 98.4 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80079.1 - 3.9e-17 62.5 0.0 1.2e-16 60.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80079.1 - 2.8e-10 40.1 0.0 9.5e-10 38.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG80079.1 - 8.9e-07 28.8 0.0 2.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG80079.1 - 2.3e-06 27.6 0.0 5.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG80079.1 - 3.3e-05 24.5 0.0 0.00019 22.0 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80079.1 - 0.00097 19.7 0.0 0.0036 17.8 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG80079.1 - 0.0048 17.1 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein NCBP3 PF10309.9 GBG80079.1 - 0.078 12.8 0.1 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 Nuclear cap-binding protein subunit 3 Asp_protease PF09668.10 GBG80079.1 - 0.08 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease TolA_bind_tri PF16331.5 GBG80079.1 - 0.088 12.9 2.5 0.32 11.1 2.5 2.0 1 0 0 1 1 1 0 TolA binding protein trimerisation WTX PF09422.10 GBG80079.1 - 1.1 8.3 5.1 0.2 10.7 0.8 1.8 2 0 0 2 2 2 0 WTX protein Histone PF00125.24 GBG80080.1 - 7.4e-23 81.3 5.1 1.8e-22 80.1 5.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Plavaka PF18759.1 GBG80080.1 - 6.7e-21 74.9 0.3 1.4e-20 73.8 0.3 1.4 1 0 0 1 1 1 1 Plavaka transposase Dimer_Tnp_hAT PF05699.14 GBG80081.1 - 0.0029 17.3 0.1 0.0058 16.4 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG80081.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG80082.1 - 3e-18 65.7 0.3 6e-18 64.7 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG80082.1 - 0.0017 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Exo_endo_phos PF03372.23 GBG80083.1 - 6e-22 78.3 0.1 1e-21 77.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG80083.1 - 0.00044 20.1 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase CENP-B_dimeris PF09026.10 GBG80083.1 - 0.021 15.2 10.8 0.021 15.2 10.8 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Dapper PF15268.6 GBG80083.1 - 0.8 8.5 28.9 1.1 8.0 28.9 1.2 1 0 0 1 1 1 0 Dapper Retrotrans_gag PF03732.17 GBG80084.1 - 0.014 15.7 0.2 0.059 13.7 0.1 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG80085.1 - 8.6e-33 112.4 0.0 1.9e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80085.1 - 1.1e-29 102.8 0.1 2.6e-29 101.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80085.1 - 5.1e-14 52.5 0.1 1.5e-13 50.9 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG80085.1 - 1.6e-09 37.7 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG80085.1 - 0.001 18.8 0.8 0.0052 16.5 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) Chromo PF00385.24 GBG80085.1 - 0.09 12.7 0.3 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain ATG16 PF08614.11 GBG80086.1 - 0.24 11.6 1.5 0.42 10.8 1.5 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Integrase_H2C2 PF17921.1 GBG80087.1 - 4.4e-18 65.1 0.4 7.9e-18 64.3 0.4 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80087.1 - 2.1e-14 53.6 0.0 3.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80087.1 - 0.078 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80087.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain APG17 PF04108.12 GBG80087.1 - 0.18 10.9 0.2 0.29 10.2 0.0 1.4 2 0 0 2 2 2 0 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG80089.1 - 1.5e-22 79.5 0.0 3.2e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80089.1 - 1e-19 70.7 0.0 2.2e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80089.1 - 0.001 18.6 0.0 0.0034 16.9 0.0 1.9 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TAF4 PF05236.14 GBG80089.1 - 2.4 7.9 12.6 4.3 7.0 12.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Integrase_H2C2 PF17921.1 GBG80090.1 - 5.2e-11 42.5 0.8 1.3e-10 41.2 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG80090.1 - 3.8e-10 40.0 0.0 8.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG80090.1 - 4.5e-10 39.3 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG80090.1 - 0.046 13.9 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Dppa2_A PF14049.6 GBG80090.1 - 0.056 13.6 0.4 0.15 12.2 0.4 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates gag-asp_proteas PF13975.6 GBG80091.1 - 4.2e-05 24.0 0.1 0.00011 22.7 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80091.1 - 7.1e-05 23.4 0.0 0.00019 22.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80091.1 - 0.0039 17.0 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG80091.1 - 0.053 13.3 0.0 0.19 11.5 0.0 1.9 2 1 0 2 2 2 0 Retroviral aspartyl protease DBD_Tnp_Hermes PF10683.9 GBG80092.1 - 1.8e-06 27.5 0.0 3.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain Neurexophilin PF06312.12 GBG80092.1 - 0.069 12.6 0.9 0.17 11.3 0.5 1.8 1 1 1 2 2 2 0 Neurexophilin Integrase_H2C2 PF17921.1 GBG80093.1 - 3.7e-14 52.6 0.0 8.1e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80093.1 - 4.4e-11 43.0 0.0 8.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG80093.1 - 0.0002 21.9 0.1 0.00046 20.7 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG80093.1 - 0.00041 20.1 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG80093.1 - 0.00059 19.6 0.4 0.002 17.9 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG80093.1 - 0.0033 18.0 0.1 0.0069 17.0 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG80093.1 - 0.0099 16.2 0.1 0.03 14.6 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG80093.1 - 0.032 14.4 0.1 0.08 13.2 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG80094.1 - 4e-34 116.6 0.0 8.3e-34 115.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80094.1 - 1.3e-30 105.8 0.0 3e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80094.1 - 3.1e-15 56.4 0.0 1.7e-14 54.0 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain Tup_N PF08581.10 GBG80094.1 - 5.2 7.5 5.7 4.2 7.7 1.2 2.6 2 0 0 2 2 2 0 Tup N-terminal RVT_1 PF00078.27 GBG80095.1 - 1.8e-27 96.3 0.1 3.2e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80095.1 - 1.1e-21 77.1 0.1 3.2e-21 75.6 0.0 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80095.1 - 2.2e-21 75.8 0.0 2.1e-20 72.6 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80095.1 - 7.9e-16 57.9 0.6 7.9e-16 57.9 0.6 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG80095.1 - 1.4e-08 34.6 0.0 3.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80095.1 - 2.3e-08 34.5 0.0 7.3e-08 32.9 0.0 1.8 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80095.1 - 5.2e-06 26.9 0.0 2e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80095.1 - 0.0031 17.3 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG80095.1 - 0.004 17.4 0.1 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein SlyX PF04102.12 GBG80095.1 - 0.019 15.6 8.0 0.062 13.9 0.3 3.6 4 0 0 4 4 4 0 SlyX Integrin_b_cyt PF08725.11 GBG80095.1 - 0.055 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain AMP-binding_C_2 PF14535.6 GBG80095.1 - 0.09 13.1 0.0 0.7 10.2 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain TolA_bind_tri PF16331.5 GBG80095.1 - 0.37 10.9 5.0 0.93 9.6 5.0 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation Asp_protease_2 PF13650.6 GBG80096.1 - 5.3e-06 27.0 0.0 1.5e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80096.1 - 6.8e-06 26.6 0.1 2.8e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG80096.1 - 0.014 15.4 2.6 0.037 14.1 2.6 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG80097.1 - 3.1e-25 89.0 0.1 5.3e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80097.1 - 6.5e-19 67.8 0.2 6.5e-19 67.8 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG80097.1 - 1.7e-11 44.4 0.0 7.6e-11 42.2 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG80097.1 - 2.3e-06 28.1 0.0 5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80097.1 - 2.9e-06 27.8 0.0 7.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80097.1 - 2.6e-05 24.0 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80097.1 - 0.0047 16.7 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG80097.1 - 0.011 15.6 0.3 0.027 14.4 0.0 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG80097.1 - 0.026 14.8 0.1 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG80097.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG80098.1 - 1.1e-26 92.7 0.0 4.3e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80098.1 - 5.8e-26 91.4 0.0 1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80098.1 - 7.8e-24 84.0 0.0 2.6e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG80098.1 - 7.7e-07 29.7 0.0 1.7e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80098.1 - 2.4e-06 28.0 0.0 4.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80098.1 - 6e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG80098.1 - 0.0013 19.0 0.0 0.0047 17.2 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein COX_ARM PF06481.14 GBG80098.1 - 0.39 10.6 1.8 7.4 6.6 0.1 3.2 4 0 0 4 4 4 0 COX Aromatic Rich Motif Retrotrans_gag PF03732.17 GBG80099.1 - 0.0053 17.0 0.2 0.015 15.6 0.2 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein SKA1 PF07160.12 GBG80099.1 - 0.033 14.0 1.6 0.18 11.6 0.1 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Angiomotin_C PF12240.8 GBG80099.1 - 0.18 11.3 2.7 0.13 11.8 0.2 2.0 2 0 0 2 2 2 0 Angiomotin C terminal IMPDH PF00478.25 GBG80100.1 - 5.4e-124 413.7 2.4 6.3e-124 413.4 2.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 GBG80100.1 - 2.4e-13 50.3 0.6 3.1e-08 33.9 0.0 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 GBG80100.1 - 6.3e-13 48.8 3.5 2.4e-10 40.3 1.8 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 GBG80100.1 - 9.6e-10 38.0 0.6 1.7e-09 37.2 0.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 GBG80100.1 - 1.4e-05 24.7 2.4 4.6e-05 23.0 1.8 2.2 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 GBG80100.1 - 3.8e-05 23.1 0.5 7.9e-05 22.1 0.5 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG BATS PF06968.13 GBG80100.1 - 0.003 17.6 0.0 0.32 11.2 0.0 2.7 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain PK PF00224.21 GBG80100.1 - 0.03 13.2 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Glu_synthase PF01645.17 GBG80100.1 - 0.039 13.1 0.3 0.062 12.4 0.3 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase IGPS PF00218.21 GBG80100.1 - 0.049 12.8 0.0 4.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF561 PF04481.12 GBG80100.1 - 0.061 12.5 0.1 0.15 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Aldolase PF01081.19 GBG80100.1 - 0.11 12.0 0.2 1 8.8 0.0 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase zf-CCHC PF00098.23 GBG80103.1 - 1.5e-09 37.5 2.6 2.6e-09 36.8 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG80103.1 - 9.4e-05 22.3 2.2 0.00011 22.1 0.6 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG80103.1 - 0.0039 16.9 1.1 0.0065 16.2 1.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG80103.1 - 0.015 15.2 0.6 0.045 13.6 0.6 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG80103.1 - 0.02 14.7 3.9 0.032 14.0 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG80106.1 - 1.3e-25 89.3 0.0 2.2e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80106.1 - 5.7e-22 78.0 0.0 1.2e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80106.1 - 1.9e-14 53.7 0.1 3.1e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG80106.1 - 0.17 10.1 5.9 0.22 9.7 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG80106.1 - 1.4 7.1 6.6 1.9 6.7 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG80106.1 - 4 6.8 9.2 5.4 6.3 9.2 1.1 1 0 0 1 1 1 0 SDA1 SIR4_SID PF16991.5 GBG80106.1 - 4.2 7.4 4.3 7.4 6.6 4.3 1.3 1 0 0 1 1 1 0 Sir4 SID domain RVT_1 PF00078.27 GBG80107.1 - 6.7e-09 35.6 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Serinc PF03348.15 GBG80107.1 - 0.0061 15.5 2.1 0.01 14.8 2.1 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) RNA_pol_Rpc4 PF05132.14 GBG80107.1 - 1.7 9.1 5.2 2.7 8.4 5.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4746 PF15928.5 GBG80107.1 - 4.6 6.6 17.9 7 6.0 17.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) zf-CCHC PF00098.23 GBG80108.1 - 9.2e-09 35.0 1.4 1.9e-08 34.0 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG80108.1 - 0.00024 20.8 2.0 0.00055 19.7 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG80108.1 - 0.13 12.8 0.0 0.55 10.8 0.0 2.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CDC45 PF02724.14 GBG80108.1 - 0.55 8.5 10.8 0.7 8.1 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG80108.1 - 1.9 6.6 14.4 3.1 5.9 14.4 1.3 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG80108.1 - 2.1 8.0 11.4 3.3 7.4 11.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG80108.1 - 3.2 7.1 14.6 5.4 6.3 14.6 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG80108.1 - 4.3 6.6 21.4 10 5.3 0.2 2.1 2 0 0 2 2 2 0 BUD22 Suc_Fer-like PF06999.12 GBG80109.1 - 1.2e-21 77.5 0.0 1.9e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like gag-asp_proteas PF13975.6 GBG80110.1 - 8.1e-07 29.5 0.0 2.2e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80110.1 - 4.7e-06 27.2 0.0 1.2e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG80110.1 - 5.4e-06 26.2 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG80110.1 - 2.1e-05 24.7 5.5 0.0011 19.2 0.1 4.1 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG80110.1 - 8.4e-05 22.4 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF4618 PF15397.6 GBG80110.1 - 0.0049 16.3 0.3 0.0089 15.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) SPARC_Ca_bdg PF10591.9 GBG80110.1 - 0.17 12.2 1.6 0.89 9.9 1.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region HIP1_clath_bdg PF16515.5 GBG80110.1 - 1 10.0 10.4 0.034 14.8 2.9 2.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Speriolin_N PF15058.6 GBG80110.1 - 1.8 8.6 7.0 14 5.7 2.9 2.4 2 0 0 2 2 2 0 Speriolin N terminus CLZ PF16526.5 GBG80110.1 - 5.6 7.4 6.8 4.2 7.8 2.6 2.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Retrotrans_gag PF03732.17 GBG80111.1 - 0.081 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein SDA1 PF05285.12 GBG80114.1 - 0.25 10.7 19.5 0.47 9.8 19.5 1.3 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG80114.1 - 0.31 11.3 12.6 0.5 10.6 12.6 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG80114.1 - 0.58 8.3 17.4 0.83 7.8 17.4 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG80114.1 - 1.6 8.0 17.4 2.3 7.5 17.4 1.2 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 GBG80114.1 - 1.9 7.9 13.5 2.9 7.3 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 GBG80114.1 - 3.8 5.7 13.0 5.7 5.1 13.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG80114.1 - 4.5 6.8 7.9 6.9 6.1 7.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF659 PF04937.15 GBG80117.1 - 2.7e-12 46.8 0.0 3.9e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CDC27 PF09507.10 GBG80117.1 - 0.018 14.4 0.3 0.018 14.4 0.3 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Dimer_Tnp_hAT PF05699.14 GBG80117.1 - 0.046 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Pro_isomerase PF00160.21 GBG80118.1 - 6.6e-46 156.5 0.2 8.1e-46 156.2 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3577 PF12101.8 GBG80118.1 - 0.14 11.9 0.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3577) Myb_DNA-bind_4 PF13837.6 GBG80119.1 - 3.2e-10 40.2 5.2 3.2e-10 40.2 5.2 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG80119.1 - 0.0019 18.4 0.2 0.0045 17.1 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-CCHC PF00098.23 GBG80120.1 - 7.9e-07 28.9 2.2 1.6e-06 27.9 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG80120.1 - 0.033 14.0 3.9 0.069 13.0 3.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Borrelia_P83 PF05262.11 GBG80120.1 - 0.042 12.3 12.5 0.05 12.1 12.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein hDGE_amylase PF14701.6 GBG80120.1 - 0.28 10.2 5.6 0.4 9.7 5.6 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Preseq_ALAS PF09029.10 GBG80120.1 - 1.7 9.2 8.4 0.11 13.0 1.7 2.4 1 1 2 3 3 3 0 5-aminolevulinate synthase presequence VIT1 PF01988.19 GBG80120.1 - 4.8 7.0 4.9 7.5 6.4 4.9 1.4 1 0 0 1 1 1 0 VIT family LUC7 PF03194.15 GBG80121.1 - 0.1 12.2 8.8 0.14 11.8 8.8 1.2 1 0 0 1 1 1 0 LUC7 N_terminus RVT_1 PF00078.27 GBG80123.1 - 4.6e-13 49.2 0.0 8.3e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80123.1 - 1.5e-09 37.8 0.0 3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80123.1 - 2.3e-06 28.2 0.0 6.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80123.1 - 2.8e-05 24.6 0.1 8.8e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80123.1 - 0.0024 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG80123.1 - 0.031 14.6 0.0 0.095 13.0 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Glyco_transf_29 PF00777.18 GBG80124.1 - 1.2e-36 126.5 0.4 2.5e-18 66.4 0.2 2.0 1 1 1 2 2 2 2 Glycosyltransferase family 29 (sialyltransferase) Myb_DNA-bind_4 PF13837.6 GBG80125.1 - 6.8e-08 32.8 0.3 1.8e-07 31.4 0.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG80125.1 - 0.042 14.2 0.1 0.093 13.1 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4400 PF14348.6 GBG80125.1 - 2.5 7.6 4.2 4 6.9 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) DDE_Tnp_4 PF13359.6 GBG80126.1 - 2.6e-14 53.2 0.0 4.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80126.1 - 0.00063 19.4 0.0 0.00097 18.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein CDC27 PF09507.10 GBG80127.1 - 0.00071 19.1 49.3 0.001 18.6 49.3 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 RVT_1 PF00078.27 GBG80128.1 - 3.9e-29 101.7 0.1 6e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80128.1 - 1.6e-15 57.3 0.1 3.5e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80128.1 - 1.1e-08 35.0 0.0 2.8e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80128.1 - 1.8e-08 34.6 0.0 4.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG80128.1 - 0.0029 17.5 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Integrase_H2C2 PF17921.1 GBG80128.1 - 0.0064 16.6 0.2 0.014 15.5 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80130.1 - 4.4e-16 59.1 0.0 6.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCD48 PF15799.5 GBG80130.1 - 0.002 16.5 2.5 0.0029 16.0 2.5 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 APG17 PF04108.12 GBG80130.1 - 0.0092 15.1 0.2 0.046 12.8 0.0 2.0 2 0 0 2 2 2 1 Autophagy protein Apg17 HALZ PF02183.18 GBG80130.1 - 0.015 15.5 1.3 0.038 14.2 1.3 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DMPK_coil PF08826.10 GBG80130.1 - 0.019 15.1 6.2 0.61 10.2 1.4 2.7 2 0 0 2 2 2 0 DMPK coiled coil domain like CCDC85 PF10226.9 GBG80130.1 - 0.041 13.6 0.2 0.041 13.6 0.2 2.1 2 0 0 2 2 2 0 CCDC85 family DivIC PF04977.15 GBG80130.1 - 0.062 13.1 1.7 0.17 11.7 1.7 1.7 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 GBG80130.1 - 0.083 13.0 1.2 0.21 11.7 1.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor GvpL_GvpF PF06386.11 GBG80130.1 - 1.9 8.4 8.9 1.6 8.6 5.2 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.15 GBG80130.1 - 4.2 7.5 12.0 0.069 13.2 3.1 2.5 3 0 0 3 3 3 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 GBG80130.1 - 4.9 7.5 6.9 0.45 10.8 1.0 2.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain XS PF03468.14 GBG80132.1 - 5.7e-05 23.4 0.0 0.00052 20.3 0.0 2.5 3 0 0 3 3 3 1 XS domain TSC22 PF01166.18 GBG80132.1 - 2 8.8 4.3 1.1 9.6 0.5 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Retrotrans_gag PF03732.17 GBG80133.1 - 0.0022 18.3 3.6 0.0049 17.1 0.0 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein Rotamase_3 PF13616.6 GBG80134.1 - 1.1e-17 64.6 0.0 1.5e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 GBG80134.1 - 4.7e-17 62.7 0.0 7e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GBG80134.1 - 0.0093 16.8 0.0 0.012 16.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain ISG65-75 PF11727.8 GBG80136.1 - 3.5 6.8 23.4 0.2 10.9 2.7 2.4 1 1 0 2 2 2 0 Invariant surface glycoprotein Terminase_6 PF03237.15 GBG80136.1 - 9.5 5.8 7.5 0.34 10.5 0.8 2.1 2 1 1 3 3 3 0 Terminase-like family DUF1565 PF07602.11 GBG80137.1 - 1.6e-07 30.9 6.8 1.2e-05 24.7 4.2 3.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1565) Beta_helix PF13229.6 GBG80137.1 - 9.8e-05 22.2 1.6 9.8e-05 22.2 1.6 2.3 1 1 1 2 2 2 2 Right handed beta helix region Sec6 PF06046.13 GBG80138.1 - 1e-92 311.4 0.0 1.6e-92 310.7 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Sec20 PF03908.13 GBG80138.1 - 0.12 12.3 0.9 0.74 9.8 0.1 2.5 1 1 1 2 2 2 0 Sec20 DUF725 PF05267.12 GBG80138.1 - 0.17 11.9 4.9 0.14 12.1 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF725) DDE_Tnp_4 PF13359.6 GBG80140.1 - 3.5e-18 65.8 0.0 6.2e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80140.1 - 3.1e-09 36.7 0.0 9.8e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG80141.1 - 0.0089 16.4 3.6 0.0089 16.4 3.6 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Glyco_transf_10 PF00852.19 GBG80142.1 - 3.8e-29 101.6 0.0 6.7e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_trans_1_2 PF13524.6 GBG80142.1 - 0.0081 16.5 0.2 0.027 14.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF4793 PF16041.5 GBG80143.1 - 0.08 13.1 0.1 17 5.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4793) CBM_2 PF00553.19 GBG80143.1 - 0.09 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Cellulose binding domain PPP4R2 PF09184.11 GBG80144.1 - 2.8 7.4 8.2 4.6 6.7 8.2 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 GBG80144.1 - 3.6 5.8 11.9 6.1 5.0 11.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG80144.1 - 9.1 4.3 13.8 13 3.8 13.8 1.1 1 0 0 1 1 1 0 Nop14-like family Integrase_H2C2 PF17921.1 GBG80146.1 - 1.1e-13 51.0 0.4 2.9e-13 49.7 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80146.1 - 1.5e-10 41.3 0.0 4.3e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG80146.1 - 5.2e-08 32.7 0.0 9.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG80146.1 - 1.3e-06 28.9 0.1 5e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80146.1 - 7e-05 23.4 0.0 0.0002 21.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG80146.1 - 9.4e-05 22.6 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG80146.1 - 0.034 14.4 0.8 0.084 13.1 0.8 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG80146.1 - 0.057 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG80146.1 - 0.067 13.0 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Aspartyl protease SeqA_N PF17206.3 GBG80146.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 SeqA protein N-terminal domain ABC_tran PF00005.27 GBG80147.1 - 7.9e-15 55.6 0.2 3.8e-07 30.7 0.1 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GBG80147.1 - 6.9e-13 49.1 0.7 3.4e-06 27.1 0.0 2.7 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GBG80147.1 - 0.002 18.7 1.8 0.016 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GBG80147.1 - 0.0046 16.7 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 GBG80147.1 - 0.0056 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 GBG80147.1 - 0.009 15.8 0.7 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Arf PF00025.21 GBG80147.1 - 0.028 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.29 GBG80147.1 - 0.084 13.3 0.3 0.32 11.4 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GBG80147.1 - 0.095 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 GBG80147.1 - 0.11 10.0 0.0 0.11 10.0 0.0 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SRP54 PF00448.22 GBG80147.1 - 0.21 11.2 0.2 0.4 10.3 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 GBG80147.1 - 0.29 11.7 1.4 0.46 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain RT_RNaseH_2 PF17919.1 GBG80148.1 - 4e-32 110.2 0.0 4.7e-31 106.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80148.1 - 8.6e-32 109.6 0.2 1.7e-30 105.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80148.1 - 1.2e-18 66.9 0.7 3e-18 65.7 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80148.1 - 1.7e-16 60.5 0.0 4.1e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG80148.1 - 5e-05 22.9 0.3 0.0001 21.9 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG80148.1 - 0.0037 17.5 0.1 0.0096 16.1 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG80148.1 - 0.13 11.9 0.1 0.13 11.9 0.1 3.5 3 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase rve PF00665.26 GBG80149.1 - 4e-12 46.4 0.0 9.3e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG80149.1 - 0.00021 21.1 0.3 0.00052 19.9 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2497 PF10691.9 GBG80149.1 - 0.11 12.9 0.1 0.46 11.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) PQQ_2 PF13360.6 GBG80152.1 - 4.8e-18 65.6 2.6 7.3e-10 38.8 0.3 2.3 2 0 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 GBG80152.1 - 1.1e-09 38.4 12.4 0.00077 19.9 0.0 5.3 5 0 0 5 5 5 4 PQQ-like domain PQQ PF01011.21 GBG80152.1 - 6.8e-06 25.8 0.6 0.9 9.6 0.0 4.3 4 0 0 4 4 4 2 PQQ enzyme repeat Glyco_tranf_2_4 PF13704.6 GBG80153.1 - 1.5e-07 31.8 0.1 7.3e-07 29.6 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 GBG80153.1 - 0.0015 18.3 0.3 0.0038 16.9 0.3 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 92 TMEM189_B_dmain PF10520.9 GBG80155.1 - 6e-54 182.8 2.3 1.5e-29 103.3 0.8 2.2 2 0 0 2 2 2 2 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 GBG80155.1 - 0.0086 16.4 8.9 0.0086 16.4 8.9 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TPR_1 PF00515.28 GBG80156.1 - 4e-56 184.7 17.0 5.2e-09 35.6 0.2 10.1 9 0 0 9 9 9 8 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 GBG80156.1 - 1.1e-53 182.3 0.0 1.2e-27 96.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 GBG80156.1 - 5.8e-39 129.1 9.5 5.1e-06 26.2 0.1 9.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 GBG80156.1 - 2.5e-38 129.5 21.0 1.3e-07 31.2 0.0 11.8 6 4 6 12 12 12 10 TPR repeat TPR_8 PF13181.6 GBG80156.1 - 1.7e-34 115.1 6.3 3.5e-06 26.8 0.0 8.8 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 GBG80156.1 - 2.3e-34 114.9 2.3 1.3e-05 24.9 0.0 8.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 GBG80156.1 - 4.4e-30 101.9 21.4 0.0018 18.5 0.1 11.2 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 GBG80156.1 - 2.8e-29 101.2 16.2 1.2e-06 28.7 0.0 7.9 7 1 0 7 7 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 GBG80156.1 - 6.6e-27 92.6 15.3 0.00085 19.1 0.1 10.1 8 1 1 9 9 9 6 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 GBG80156.1 - 9.9e-23 80.1 0.0 2.1e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80156.1 - 2e-20 73.0 0.1 6e-20 71.5 0.0 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase TPR_19 PF14559.6 GBG80156.1 - 7e-20 71.3 10.7 0.008 16.7 0.0 7.9 4 3 3 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 GBG80156.1 - 6.9e-19 68.2 10.9 2.2e-05 25.0 0.0 7.6 5 2 1 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 GBG80156.1 - 2.9e-16 58.8 2.8 0.14 13.0 0.0 9.6 4 4 6 10 10 10 3 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 GBG80156.1 - 1.3e-14 54.4 6.3 2.4e-07 30.5 0.1 4.5 4 1 1 5 5 5 2 Est1 DNA/RNA binding domain TPR_9 PF13371.6 GBG80156.1 - 7.6e-14 51.6 5.1 0.00096 19.3 0.0 6.6 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 GBG80156.1 - 3.5e-12 46.1 8.0 0.19 12.4 0.0 9.2 9 0 0 9 9 9 2 Tetratricopeptide repeat NARP1 PF12569.8 GBG80156.1 - 3.4e-08 32.9 4.6 0.011 14.7 0.1 4.1 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 GBG80156.1 - 3.3e-05 23.3 0.0 0.0071 15.6 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG80156.1 - 4.8e-05 22.9 0.4 0.16 11.3 0.0 3.7 2 1 1 4 4 4 2 MalT-like TPR region TPR_4 PF07721.14 GBG80156.1 - 0.0018 18.7 0.0 30 5.6 0.0 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 GBG80156.1 - 0.013 15.8 0.1 0.058 13.7 0.1 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein RPN7 PF10602.9 GBG80156.1 - 0.031 14.0 0.4 1.6 8.4 0.1 3.5 2 1 1 3 3 3 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 GBG80156.1 - 0.051 13.8 3.5 8.1 6.7 0.1 3.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4407 PF14362.6 GBG80156.1 - 2.1 7.6 7.9 5 6.4 7.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_1 PF00515.28 GBG80157.1 - 7.7e-58 190.1 14.7 5.1e-09 35.6 0.2 10.0 9 0 0 9 9 9 8 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 GBG80157.1 - 1.1e-53 182.4 0.0 1.1e-27 96.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.6 GBG80157.1 - 7.2e-41 137.6 19.7 1.3e-07 31.2 0.0 11.8 6 4 6 12 12 12 10 TPR repeat TPR_2 PF07719.17 GBG80157.1 - 1.9e-40 133.7 7.6 5.1e-06 26.2 0.1 9.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 GBG80157.1 - 1.8e-36 121.2 2.5 3.5e-06 26.8 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 GBG80157.1 - 2.3e-34 114.9 0.6 1.3e-05 24.9 0.0 8.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 GBG80157.1 - 1.3e-29 102.3 13.3 4.5e-06 26.9 0.0 7.9 7 1 0 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 GBG80157.1 - 3.4e-29 99.1 23.6 0.0018 18.5 0.1 11.9 12 0 0 12 12 11 8 Tetratricopeptide repeat TPR_10 PF13374.6 GBG80157.1 - 1.9e-26 91.1 14.1 0.0011 18.8 0.1 10.1 8 1 1 9 9 9 6 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 GBG80157.1 - 9.8e-23 80.1 0.0 2.1e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80157.1 - 2e-20 73.0 0.1 5.9e-20 71.5 0.0 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase TPR_19 PF14559.6 GBG80157.1 - 5e-20 71.8 11.9 0.0064 17.0 0.0 8.2 4 4 4 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 GBG80157.1 - 7e-20 71.4 8.8 9.7e-06 26.1 0.0 7.6 5 2 1 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 GBG80157.1 - 1.1e-17 63.2 2.0 0.14 13.1 0.0 9.6 4 4 6 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 GBG80157.1 - 1.4e-15 57.1 3.8 0.00095 19.3 0.0 6.6 5 2 1 6 6 6 3 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 GBG80157.1 - 5.6e-15 55.6 4.5 2.3e-07 30.6 0.1 4.4 4 0 0 4 4 4 2 Est1 DNA/RNA binding domain TPR_6 PF13174.6 GBG80157.1 - 1.8e-14 53.3 6.9 0.19 12.4 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat NARP1 PF12569.8 GBG80157.1 - 1.4e-07 30.8 3.5 0.01 14.8 0.1 4.1 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 GBG80157.1 - 7e-06 25.4 0.0 0.007 15.6 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG80157.1 - 6.1e-05 22.5 0.8 0.16 11.3 0.0 3.8 2 1 1 4 4 4 2 MalT-like TPR region TPR_4 PF07721.14 GBG80157.1 - 0.0083 16.7 0.0 30 5.7 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 GBG80157.1 - 0.012 15.8 0.1 0.057 13.7 0.1 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein ANAPC3 PF12895.7 GBG80157.1 - 0.056 13.7 3.5 8.1 6.8 0.1 3.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 GBG80157.1 - 0.12 12.1 0.5 1.6 8.4 0.1 3.1 2 1 1 3 3 3 0 26S proteasome subunit RPN7 DUF4407 PF14362.6 GBG80157.1 - 1.7 7.9 7.6 4 6.7 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_1 PF00515.28 GBG80158.1 - 4.4e-56 184.6 17.0 5.1e-09 35.6 0.2 10.0 9 0 0 9 9 9 8 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 GBG80158.1 - 1.1e-53 182.4 0.0 1.1e-27 96.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 GBG80158.1 - 6.1e-39 129.0 9.5 5.1e-06 26.2 0.1 9.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 GBG80158.1 - 2.3e-38 129.6 20.9 1.3e-07 31.2 0.0 11.8 6 4 6 12 12 12 10 TPR repeat TPR_8 PF13181.6 GBG80158.1 - 6.3e-35 116.5 4.6 3.5e-06 26.8 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 GBG80158.1 - 2.3e-34 114.9 2.3 1.3e-05 24.9 0.0 8.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 GBG80158.1 - 4.6e-30 101.8 21.4 0.0018 18.5 0.1 11.1 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 GBG80158.1 - 2.9e-29 101.2 16.3 1.2e-06 28.7 0.0 7.9 7 1 0 7 7 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 GBG80158.1 - 6.3e-27 92.6 15.3 0.00084 19.1 0.1 10.1 8 1 1 9 9 9 6 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 GBG80158.1 - 9.8e-23 80.1 0.0 2.1e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80158.1 - 2e-20 73.0 0.1 5.9e-20 71.5 0.0 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase TPR_19 PF14559.6 GBG80158.1 - 3.1e-19 69.2 13.3 0.0064 17.0 0.0 8.0 4 4 3 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 GBG80158.1 - 5.1e-19 68.6 10.5 2.1e-05 25.0 0.0 7.6 5 2 1 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 GBG80158.1 - 3.2e-16 58.6 3.1 0.14 13.1 0.0 9.5 4 4 6 10 10 10 3 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 GBG80158.1 - 8.2e-15 55.0 6.7 2.3e-07 30.6 0.1 4.6 4 1 1 5 5 5 2 Est1 DNA/RNA binding domain TPR_9 PF13371.6 GBG80158.1 - 9.1e-14 51.4 5.6 0.00095 19.3 0.0 6.6 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 GBG80158.1 - 3.3e-12 46.2 8.0 0.19 12.4 0.0 9.2 9 0 0 9 9 9 2 Tetratricopeptide repeat NARP1 PF12569.8 GBG80158.1 - 4.3e-08 32.5 5.2 0.01 14.8 0.1 4.1 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 GBG80158.1 - 1.1e-05 24.8 0.1 0.007 15.6 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG80158.1 - 9.4e-05 21.9 1.4 0.16 11.3 0.0 3.8 2 1 1 4 4 4 2 MalT-like TPR region TPR_4 PF07721.14 GBG80158.1 - 0.0017 18.8 0.0 30 5.7 0.0 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 GBG80158.1 - 0.012 15.8 0.1 0.057 13.7 0.1 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein RPN7 PF10602.9 GBG80158.1 - 0.032 14.0 0.3 1.6 8.4 0.1 3.5 2 1 1 3 3 3 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 GBG80158.1 - 0.049 13.9 3.5 8.1 6.8 0.1 3.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4407 PF14362.6 GBG80158.1 - 1.7 7.9 7.6 4 6.7 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) N6_N4_Mtase PF01555.18 GBG80160.1 - 1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 DNA methylase TTSSLRR PF12468.8 GBG80160.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Cons_hypoth95 PF03602.15 GBG80160.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF421 PF04239.12 GBG80161.1 - 0.031 14.0 0.2 0.065 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Retrotrans_gag PF03732.17 GBG80161.1 - 3.5 8.0 10.4 19 5.6 0.1 4.1 3 1 0 3 3 3 0 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG80161.1 - 6.2 7.5 23.0 0.086 13.5 6.1 3.7 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GIT_CC PF16559.5 GBG80161.1 - 7.3 6.5 11.0 16 5.5 0.0 3.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3138 PF11336.8 GBG80161.1 - 9.9 4.6 8.0 23 3.4 7.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Integrase_H2C2 PF17921.1 GBG80165.1 - 1.5e-15 57.1 0.1 3.8e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80165.1 - 2.4e-10 40.3 0.0 3.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG80165.1 - 1.7e-05 25.3 0.0 4.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80165.1 - 0.00062 20.4 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG80165.1 - 0.0029 17.8 0.1 0.01 16.0 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease PF09668.10 GBG80165.1 - 0.0068 16.2 0.4 0.014 15.2 0.4 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG80165.1 - 0.18 12.1 0.0 0.49 10.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RPN2_C PF18004.1 GBG80165.1 - 7.7 6.4 7.7 27 4.7 7.7 1.9 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Peptidase_C48 PF02902.19 GBG80167.1 - 3.5e-18 66.2 0.0 9.7e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain N6_N4_Mtase PF01555.18 GBG80167.1 - 7.8e-08 32.3 0.0 4.8e-07 29.7 0.0 2.3 2 1 0 2 2 2 1 DNA methylase DUF659 PF04937.15 GBG80170.1 - 1.8e-18 66.8 0.0 2.6e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80170.1 - 0.0028 17.4 0.1 0.0058 16.4 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG80172.1 - 0.0013 18.6 0.0 0.027 14.3 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) Glu_syn_central PF04898.14 GBG80172.1 - 0.22 10.9 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Glutamate synthase central domain Retrotrans_gag PF03732.17 GBG80174.1 - 4.8e-05 23.6 0.2 4.8e-05 23.6 0.2 3.3 4 0 0 4 4 4 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG80174.1 - 0.17 12.4 0.3 3.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AIF-MLS PF14962.6 GBG80174.1 - 0.25 11.3 3.5 0.46 10.4 3.5 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Histone_HNS PF00816.21 GBG80174.1 - 2 9.3 8.7 66 4.4 6.5 3.1 3 0 0 3 3 3 0 H-NS histone family FlxA PF14282.6 GBG80174.1 - 3.9 7.5 14.2 10 6.2 0.0 3.4 3 1 1 4 4 4 0 FlxA-like protein RT_RNaseH_2 PF17919.1 GBG80175.1 - 1.1e-27 96.0 0.0 1.6e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80175.1 - 7.6e-26 90.5 0.0 1.3e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80175.1 - 8.7e-06 25.8 0.1 2.1e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain EF-hand_7 PF13499.6 GBG80176.1 - 4.8e-05 23.7 2.9 0.00015 22.2 0.0 3.1 3 1 0 3 3 3 1 EF-hand domain pair TFIIA PF03153.13 GBG80176.1 - 0.019 15.0 9.4 0.028 14.4 9.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF-hand_6 PF13405.6 GBG80176.1 - 0.1 12.6 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Hemagglutinin PF00509.18 GBG80176.1 - 2.7 6.3 4.0 4.4 5.6 4.0 1.2 1 0 0 1 1 1 0 Haemagglutinin YL1 PF05764.13 GBG80177.1 - 0.89 9.6 27.6 0.13 12.4 18.5 2.2 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 GBG80179.1 - 0.78 8.0 23.9 0.95 7.7 23.9 1.1 1 0 0 1 1 1 0 CDC45-like protein ATP-synt_E PF05680.12 GBG80180.1 - 1.4 9.3 17.9 1.8 9.0 11.4 2.4 2 0 0 2 2 2 0 ATP synthase E chain DUF4522 PF15022.6 GBG80180.1 - 9.8 6.5 8.7 0.71 10.1 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) BSP_II PF05432.11 GBG80182.1 - 0.041 13.6 28.4 0.056 13.1 28.2 1.3 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) Lin-8 PF03353.15 GBG80182.1 - 0.15 11.6 8.3 0.17 11.4 8.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG80182.1 - 0.23 9.6 14.5 0.27 9.4 14.5 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG80182.1 - 0.28 10.5 24.1 0.31 10.3 24.1 1.1 1 0 0 1 1 1 0 BUD22 CENP-B_dimeris PF09026.10 GBG80182.1 - 0.7 10.3 13.4 1.6 9.1 13.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 GBG80182.1 - 1.2 7.3 17.6 1.5 7.0 17.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG80182.1 - 1.8 7.9 11.9 0.12 11.7 7.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) PAP1 PF08601.10 GBG80182.1 - 6 6.5 17.7 7.3 6.2 17.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 NOA36 PF06524.12 GBG80182.1 - 7.1 5.9 14.4 0.12 11.6 6.8 1.8 2 0 0 2 2 2 0 NOA36 protein DAP PF15228.6 GBG80182.1 - 9.7 7.4 7.2 4.5 8.5 1.7 2.3 2 0 0 2 2 2 0 Death-associated protein DDE_Tnp_4 PF13359.6 GBG80185.1 - 5.5e-30 104.1 0.0 9.8e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80185.1 - 1.6e-11 44.2 0.0 2.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG80185.1 - 0.23 11.1 0.2 6.6 6.3 0.1 2.5 3 0 0 3 3 3 0 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG80186.1 - 1.8e-30 105.7 0.0 3.4e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80186.1 - 5.6e-12 45.7 0.0 8.8e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG80186.1 - 0.068 12.8 0.0 3.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG80187.1 - 1e-09 38.6 3.1 1e-09 38.6 0.9 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG80187.1 - 0.056 13.8 0.5 0.14 12.5 0.5 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG80192.1 - 1.1e-25 90.2 0.0 3.1e-25 88.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80192.1 - 2.2e-12 47.0 0.0 3.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG80192.1 - 0.029 14.0 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain Presenilin PF01080.17 GBG80193.1 - 0.82 8.4 2.0 1.1 8.0 2.0 1.2 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 GBG80193.1 - 3.4 5.9 14.5 4.6 5.5 14.5 1.1 1 0 0 1 1 1 0 Menin DUF2190 PF09956.9 GBG80194.1 - 0.0025 18.2 2.5 0.005 17.3 2.5 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2190) RVT_1 PF00078.27 GBG80195.1 - 9.6e-33 113.6 0.0 1.6e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80195.1 - 9.2e-13 48.4 0.0 2.1e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG80195.1 - 4.3e-12 46.0 0.0 4.5e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG80195.1 - 2.1e-07 30.8 0.0 3.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80195.1 - 7.1e-05 23.4 0.0 0.00016 22.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80195.1 - 0.00013 22.4 0.0 0.00049 20.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80195.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG80195.1 - 0.0078 16.4 0.0 0.026 14.7 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Pkinase_Tyr PF07714.17 GBG80196.1 - 1.2e-31 110.0 0.0 3.8e-31 108.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG80196.1 - 9.8e-29 100.5 0.0 2.1e-28 99.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG80196.1 - 0.00087 19.3 0.0 0.0025 17.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG80196.1 - 0.039 12.7 0.0 0.47 9.2 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Transposase_20 PF02371.16 GBG80196.1 - 0.082 13.2 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family RVT_1 PF00078.27 GBG80198.1 - 3.8e-27 95.2 0.6 2.3e-26 92.7 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80198.1 - 4.3e-23 81.2 0.0 1.4e-22 79.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80198.1 - 6.5e-23 81.0 0.0 1.3e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG80198.1 - 6.3e-08 32.5 0.0 1.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80198.1 - 6.8e-08 33.0 0.0 1.7e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80198.1 - 1.1e-05 25.9 0.0 3.1e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80198.1 - 0.0037 17.0 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease API5 PF05918.11 GBG80198.1 - 0.025 13.4 0.1 0.037 12.9 0.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DDE_Tnp_1_2 PF13586.6 GBG80200.1 - 0.1 13.0 2.4 0.32 11.4 2.4 1.8 1 0 0 1 1 1 0 Transposase DDE domain IMS PF00817.20 GBG80201.1 - 6.7e-49 165.7 0.0 1e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 GBG80201.1 - 0.0094 16.2 0.2 0.026 14.9 0.2 1.8 1 0 0 1 1 1 1 IMS family HHH motif DUF1805 PF08827.11 GBG80201.1 - 0.1 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Myb_DNA-bind_4 PF13837.6 GBG80203.1 - 6.4e-10 39.3 1.2 6.4e-10 39.3 1.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG80203.1 - 0.0052 17.1 0.1 0.015 15.6 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2514 PF10721.9 GBG80205.1 - 0.00091 19.3 4.0 0.00091 19.3 4.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2514) Linker_histone PF00538.19 GBG80206.1 - 2.2e-12 47.2 0.1 3.7e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family XhlA PF10779.9 GBG80208.1 - 0.61 10.3 9.5 0.81 9.9 0.1 3.3 2 1 1 3 3 3 0 Haemolysin XhlA JHY PF15261.6 GBG80209.1 - 1.5e-07 32.2 0.7 1.5e-07 32.2 0.7 2.3 2 0 0 2 2 2 1 Jhy protein TatD_DNase PF01026.21 GBG80209.1 - 0.071 12.5 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 TatD related DNase SCAB_CC PF16712.5 GBG80209.1 - 0.076 12.8 6.5 0.13 12.1 6.5 1.4 1 1 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein LpoB PF13036.6 GBG80209.1 - 0.27 11.2 1.7 0.41 10.6 0.3 1.9 1 1 1 2 2 2 0 Peptidoglycan-synthase activator LpoB RT_RNaseH_2 PF17919.1 GBG80211.1 - 1.4e-18 66.8 0.0 2.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80211.1 - 3.4e-11 43.1 0.1 6.8e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80211.1 - 1.5e-10 41.3 0.0 3.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG80211.1 - 5.3e-10 39.5 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG80211.1 - 0.068 12.3 0.3 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 Autophagy protein Apg17 RVT_1 PF00078.27 GBG80212.1 - 5.5e-33 114.3 0.0 9.3e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80212.1 - 3.5e-06 26.8 0.0 6.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80212.1 - 2.7e-05 24.0 0.0 5.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG80212.1 - 0.00015 22.4 0.0 0.00031 21.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80212.1 - 0.0017 18.8 0.0 0.0035 17.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Fascin PF06268.13 GBG80212.1 - 0.078 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Fascin domain SSP160 PF06933.11 GBG80212.1 - 1.5 6.9 5.4 2.4 6.2 5.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Nop14 PF04147.12 GBG80213.1 - 0.095 10.9 7.5 0.11 10.7 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG80213.1 - 0.21 11.9 10.9 0.41 10.9 10.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG80213.1 - 0.63 8.3 8.3 0.8 7.9 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG80213.1 - 1.3 8.4 10.2 1.6 8.1 10.2 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 GBG80213.1 - 1.8 7.9 10.2 2.9 7.2 10.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_photolyase PF00875.18 GBG80214.1 - 9.9e-41 139.5 0.0 3.4e-40 137.7 0.0 2.0 1 0 0 1 1 1 1 DNA photolyase RVT_1 PF00078.27 GBG80214.1 - 4.4e-27 95.0 0.1 1.2e-26 93.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80214.1 - 9.2e-20 70.6 0.0 3.9e-19 68.5 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80214.1 - 2.9e-18 65.7 0.3 8.7e-18 64.2 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG80214.1 - 2e-12 47.3 0.0 8.1e-10 38.9 0.0 2.9 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG80214.1 - 3e-06 27.8 0.0 1e-05 26.1 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80214.1 - 7e-06 26.5 0.0 1.8e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80214.1 - 4.7e-05 23.2 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80214.1 - 0.00046 20.0 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Lys-AminoMut_A PF09043.11 GBG80214.1 - 0.023 13.2 0.4 0.048 12.1 0.4 1.5 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit zf-H2C2 PF09337.10 GBG80214.1 - 0.033 14.4 0.4 0.23 11.7 0.0 2.7 2 0 0 2 2 2 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG80214.1 - 2.5 8.5 6.9 19 5.6 0.1 3.8 4 0 0 4 4 3 0 Retrotransposon gag protein FAD_binding_7 PF03441.14 GBG80215.1 - 1.5e-69 233.6 1.4 3.6e-69 232.3 1.4 1.7 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase RT_RNaseH_2 PF17919.1 GBG80215.1 - 1.5e-30 105.2 0.3 2.9e-30 104.2 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80215.1 - 1.2e-28 100.2 0.6 1.3e-27 96.8 0.6 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80215.1 - 2.3e-19 69.6 0.1 5.3e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80215.1 - 0.0002 21.5 2.4 0.029 14.6 0.4 2.7 2 0 0 2 2 2 2 Retrotransposon gag protein BaffR-Tall_bind PF09256.10 GBG80215.1 - 0.079 12.7 0.6 0.18 11.6 0.6 1.6 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding RT_RNaseH PF17917.1 GBG80216.1 - 2.4e-23 82.4 0.0 6.7e-21 74.6 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80216.1 - 6.5e-21 74.3 0.0 6.3e-20 71.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80216.1 - 0.00072 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_29 PF03141.16 GBG80217.1 - 8.1e-202 671.3 0.0 9.6e-202 671.0 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 GBG80217.1 - 3e-08 34.2 0.0 4.9e-06 27.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG80217.1 - 7.1e-06 26.7 0.0 9.7e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG80217.1 - 0.0001 22.2 0.0 0.0014 18.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG80217.1 - 0.0001 22.1 0.0 0.44 10.3 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GBG80217.1 - 0.013 16.2 0.0 1.5 9.6 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Dimer_Tnp_hAT PF05699.14 GBG80219.1 - 0.00097 18.9 0.1 0.0018 18.0 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-FCS PF06467.14 GBG80220.1 - 0.18 11.7 0.2 0.18 11.7 0.2 1.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Lipase_GDSL_2 PF13472.6 GBG80221.1 - 0.083 13.3 0.1 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Gp5_C PF06715.12 GBG80221.1 - 0.15 12.3 4.6 7.4 6.9 0.4 3.1 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) Transthyretin PF00576.21 GBG80222.1 - 3.1e-27 95.4 0.0 1.6e-25 89.9 0.0 2.8 1 1 0 1 1 1 1 HIUase/Transthyretin family OHCU_decarbox PF09349.10 GBG80222.1 - 4.8e-27 95.4 0.0 9.1e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 OHCU decarboxylase DUF659 PF04937.15 GBG80223.1 - 1.1e-22 80.5 0.0 1.7e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GTP_EFTU PF00009.27 GBG80224.1 - 2.8e-06 27.0 1.7 0.00017 21.2 0.0 2.4 3 0 0 3 3 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GBG80224.1 - 0.0002 21.7 1.9 0.01 16.2 1.9 2.5 1 1 0 1 1 1 1 Elongation factor Tu domain 2 Myc_N PF01056.18 GBG80224.1 - 0.0053 16.7 1.2 0.0073 16.2 1.2 1.2 1 0 0 1 1 1 1 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 GBG80224.1 - 0.0093 16.2 4.6 0.014 15.7 4.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.19 GBG80224.1 - 0.013 16.1 11.5 0.024 15.2 11.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein BSP_II PF05432.11 GBG80224.1 - 0.052 13.2 12.1 0.074 12.7 12.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RPN2_C PF18004.1 GBG80224.1 - 0.056 13.4 0.7 0.082 12.8 0.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Radial_spoke PF04712.12 GBG80224.1 - 0.13 11.1 8.9 0.18 10.7 8.9 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein NOA36 PF06524.12 GBG80224.1 - 0.27 10.5 6.2 0.43 9.9 6.2 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GBG80224.1 - 0.36 9.0 7.0 0.46 8.6 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG80224.1 - 0.48 9.8 5.5 0.66 9.3 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 GBG80224.1 - 1.8 6.5 9.9 2.3 6.2 9.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 GBG80224.1 - 2.1 7.3 8.3 3.3 6.6 8.3 1.2 1 0 0 1 1 1 0 Paf1 DUF2457 PF10446.9 GBG80224.1 - 2.7 7.0 10.1 3.8 6.6 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 GBG80224.1 - 9.1 6.7 13.6 25 5.3 13.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GTP_EFTU PF00009.27 GBG80225.1 - 5.3e-12 45.7 0.1 1.2e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TMEM247 PF15444.6 GBG80225.1 - 0.061 13.4 0.3 0.14 12.2 0.3 1.6 1 1 0 1 1 1 0 Transmembrane protein 247 Retrotrans_gag PF03732.17 GBG80225.1 - 0.083 13.2 0.0 0.083 13.2 0.0 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein MobB PF03205.14 GBG80225.1 - 0.18 11.7 1.4 5.3 7.0 0.1 2.7 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DDHD PF02862.17 GBG80225.1 - 5.5 7.1 6.1 1.4 9.0 2.7 1.7 1 1 1 2 2 2 0 DDHD domain NUDIX PF00293.28 GBG80226.1 - 5e-15 55.7 0.0 8.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF2095 PF09868.9 GBG80226.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) NUDIX PF00293.28 GBG80227.1 - 8e-15 55.0 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CLTH PF10607.9 GBG80229.1 - 3.1e-35 121.3 0.0 4.7e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 GBG80229.1 - 9.5e-10 38.3 1.0 2e-09 37.3 1.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG80229.1 - 8.1e-06 25.7 0.8 1.8e-05 24.6 0.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GBG80229.1 - 1.1e-05 25.5 1.4 3e-05 24.1 1.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GBG80229.1 - 5.9e-05 23.3 1.3 0.00014 22.1 1.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG80229.1 - 9.3e-05 22.2 1.5 0.00023 21.0 1.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG80229.1 - 0.00011 22.0 1.0 0.00021 21.1 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG80229.1 - 0.0008 19.2 2.0 0.0022 17.8 2.1 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GBG80229.1 - 0.0056 16.5 2.4 0.013 15.3 2.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 GBG80229.1 - 0.18 11.1 1.5 0.29 10.5 1.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger ARD PF03079.14 GBG80231.1 - 5.4e-46 156.6 0.3 5e-43 147.0 0.2 2.0 1 1 1 2 2 2 2 ARD/ARD' family Cupin_2 PF07883.11 GBG80231.1 - 5.2e-09 35.7 0.1 9.2e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 GBG80231.1 - 6.6e-07 29.3 0.1 1e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 GBG80231.1 - 0.00072 19.2 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 GBG80232.1 - 1e-45 155.7 0.3 7.6e-43 146.4 0.2 2.0 1 1 1 2 2 2 2 ARD/ARD' family Cupin_2 PF07883.11 GBG80232.1 - 6.2e-09 35.4 0.1 1.3e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 GBG80232.1 - 8.6e-07 28.9 0.1 1.4e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 GBG80232.1 - 0.00098 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Cupin PIP5K PF01504.18 GBG80233.1 - 0.021 14.1 0.0 0.14 11.4 0.0 2.0 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase RVT_1 PF00078.27 GBG80234.1 - 7.7e-31 107.3 0.0 1.3e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80234.1 - 2.8e-15 56.2 0.0 8.3e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG80234.1 - 1.1e-06 29.2 0.0 2.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80234.1 - 1.8e-06 28.4 0.0 4.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80234.1 - 8.1e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG80234.1 - 3.1e-05 24.2 0.0 9.8e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80234.1 - 0.00024 21.3 0.0 0.00064 19.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG80234.1 - 0.00064 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Hepatitis_core PF00906.20 GBG80234.1 - 0.015 14.8 2.7 0.16 11.5 0.2 2.3 2 0 0 2 2 2 0 Hepatitis core antigen Chromo PF00385.24 GBG80234.1 - 0.026 14.4 0.1 0.17 11.8 0.0 2.4 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG80234.1 - 0.041 14.1 2.8 0.12 12.7 1.2 2.6 2 1 0 2 2 2 0 Retrotransposon gag protein UPF0184 PF03670.13 GBG80234.1 - 0.1 13.0 0.2 0.91 9.9 0.0 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) Taeniidae_ag PF05596.11 GBG80236.1 - 0.028 14.4 1.0 3.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Taeniidae antigen DUF410 PF04190.13 GBG80236.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) vATP-synt_E PF01991.18 GBG80236.1 - 3.7 6.9 20.8 5.7 6.3 20.8 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit VIT1 PF01988.19 GBG80236.1 - 5.6 6.8 4.6 11 5.8 4.6 1.6 1 0 0 1 1 1 0 VIT family adh_short_C2 PF13561.6 GBG80237.1 - 1.9e-58 197.8 0.1 2.3e-58 197.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GBG80237.1 - 2.2e-51 174.1 0.1 2.6e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GBG80237.1 - 2.1e-14 53.8 0.8 2.8e-14 53.5 0.8 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 GBG80237.1 - 1.7e-05 24.2 0.0 2.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein THF_DHG_CYH_C PF02882.19 GBG80237.1 - 0.048 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 GBG80237.1 - 0.053 13.0 0.3 0.2 11.1 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Retrotrans_gag PF03732.17 GBG80238.1 - 0.00087 19.5 0.4 0.0017 18.6 0.1 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG80238.1 - 0.0017 18.1 0.7 0.0043 16.8 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Pkinase PF00069.25 GBG80240.1 - 7.5e-41 140.2 0.2 4.8e-40 137.6 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG80240.1 - 4.5e-14 52.4 0.0 7.1e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GBG80240.1 - 0.035 13.4 0.1 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG80240.1 - 0.036 14.0 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nop14 PF04147.12 GBG80241.1 - 0.21 9.7 7.1 0.24 9.6 7.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG80241.1 - 0.22 9.8 7.0 0.26 9.6 7.0 1.0 1 0 0 1 1 1 0 CDC45-like protein A2L_zn_ribbon PF08792.10 GBG80242.1 - 0.45 10.3 2.2 1.9 8.3 2.6 1.8 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF4187 PF13821.6 GBG80243.1 - 0.00049 19.8 1.2 0.002 17.9 1.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG80243.1 - 0.0018 18.5 2.4 0.006 16.8 0.5 2.6 2 1 1 3 3 3 1 Retrotransposon gag protein C1_1 PF00130.22 GBG80243.1 - 0.14 12.1 0.4 0.26 11.2 0.4 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PRIMA1 PF16101.5 GBG80244.1 - 0.0048 16.9 2.7 0.0089 16.1 2.7 1.3 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG80244.1 - 0.016 14.7 6.3 0.028 13.9 6.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GBG80244.1 - 0.16 12.1 1.7 0.36 10.9 1.7 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Rhomboid PF01694.22 GBG80245.1 - 2.4e-27 95.8 5.5 2.4e-27 95.8 5.5 1.6 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.15 GBG80245.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Der1-like family HEAT_2 PF13646.6 GBG80246.1 - 2.1e-13 50.5 23.1 0.00073 19.9 0.6 8.2 7 2 1 8 8 8 5 HEAT repeats HEAT PF02985.22 GBG80246.1 - 4.4e-09 35.8 30.5 0.06 13.6 0.2 11.0 11 0 0 11 11 11 4 HEAT repeat CLASP_N PF12348.8 GBG80246.1 - 8.8e-06 25.4 1.3 0.44 10.1 0.0 4.3 5 1 0 5 5 5 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 GBG80246.1 - 8.8e-06 26.2 3.5 3.7 8.2 0.0 6.8 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 GBG80246.1 - 0.00073 19.2 0.0 5.9 6.3 0.0 3.8 4 0 0 4 4 4 2 Tti2 family RTP1_C1 PF10363.9 GBG80246.1 - 0.0017 18.5 2.3 0.32 11.2 0.0 4.4 3 1 2 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 GBG80246.1 - 0.023 14.7 7.6 1.4 8.9 0.0 5.4 6 0 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 GBG80246.1 - 0.025 13.7 1.5 23 3.9 0.0 4.4 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 GBG80246.1 - 0.11 12.3 0.1 1.3 8.9 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 GBG80246.1 - 0.79 10.3 31.9 1.5 9.4 0.0 8.5 10 1 1 11 11 11 0 HEAT-like repeat RT_RNaseH_2 PF17919.1 GBG80247.1 - 1.6e-35 121.2 0.0 2.6e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80247.1 - 4.1e-31 107.4 0.0 6.9e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80247.1 - 1.3e-07 31.4 0.1 1.8e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Abhydrolase_6 PF12697.7 GBG80249.1 - 0.0019 18.9 0.0 0.0025 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4746 PF15928.5 GBG80249.1 - 0.093 12.1 7.1 0.13 11.7 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FAM181 PF15238.6 GBG80249.1 - 0.1 12.5 2.6 0.14 12.0 2.6 1.2 1 0 0 1 1 1 0 FAM181 WRNPLPNID PF15017.6 GBG80249.1 - 0.88 10.5 13.0 0.66 10.9 0.6 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DNA_pol_phi PF04931.13 GBG80249.1 - 1.7 6.6 8.9 2.5 6.1 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 GBG80249.1 - 8.8 6.8 8.1 5.7 7.4 1.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NUMOD3 PF07460.11 GBG80250.1 - 6.7e-10 39.0 6.7 0.0001 22.5 0.0 4.3 4 0 0 4 4 4 3 NUMOD3 motif (2 copies) HAD PF12710.7 GBG80250.1 - 0.081 13.3 0.3 0.19 12.1 0.3 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RskA PF10099.9 GBG80250.1 - 0.75 10.1 9.3 9.1 6.5 5.5 2.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA dCache_1 PF02743.18 GBG80251.1 - 0.039 13.7 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Cache domain SOG2 PF10428.9 GBG80251.1 - 2.1 7.5 18.5 3.1 6.9 18.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Myb_DNA-bind_4 PF13837.6 GBG80252.1 - 4.6e-10 39.7 1.7 1.1e-09 38.5 0.3 2.1 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG80252.1 - 0.00078 19.7 0.4 0.0026 18.0 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG80252.1 - 0.0023 18.0 0.8 0.0023 18.0 0.8 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG80252.1 - 0.0055 16.9 0.1 0.0098 16.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain FERM_N_2 PF18038.1 GBG80252.1 - 0.03 15.1 0.0 0.059 14.2 0.0 1.4 1 0 0 1 1 1 0 FERM N-terminal domain DDE_Tnp_4 PF13359.6 GBG80254.1 - 2.6e-27 95.4 0.0 4.2e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80254.1 - 5.3e-10 39.2 0.0 8.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG80254.1 - 0.21 11.2 0.4 24 4.5 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain DUF3593 PF12159.8 GBG80255.1 - 5.4e-15 55.2 1.0 8.1e-15 54.6 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) XG_FTase PF03254.13 GBG80256.1 - 4.6e-68 230.0 0.0 3.7e-47 161.0 0.0 3.7 3 1 0 3 3 3 2 Xyloglucan fucosyltransferase NodZ PF05830.11 GBG80256.1 - 0.081 11.7 0.0 0.94 8.2 0.0 2.4 3 0 0 3 3 3 0 Nodulation protein Z (NodZ) HAD_2 PF13419.6 GBG80257.1 - 3e-32 112.1 0.0 3.5e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GBG80257.1 - 6.6e-15 56.0 0.0 2.6e-13 50.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GBG80257.1 - 1.2e-08 35.5 0.0 1.8e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG80257.1 - 1.5e-06 28.1 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like OCD_Mu_crystall PF02423.15 GBG80257.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family F-box-like PF12937.7 GBG80258.1 - 1.7e-07 31.0 0.3 3e-07 30.2 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG80258.1 - 6.4e-05 22.7 0.5 0.00014 21.6 0.5 1.6 1 0 0 1 1 1 1 F-box domain Cupin_2 PF07883.11 GBG80258.1 - 0.0045 16.7 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Dimer_Tnp_hAT PF05699.14 GBG80259.1 - 3e-06 26.9 0.1 5.7e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG80259.1 - 8.1e-06 25.8 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SDA1 PF05285.12 GBG80259.1 - 0.18 11.2 17.7 0.3 10.5 17.7 1.3 1 0 0 1 1 1 0 SDA1 GREB1 PF15782.5 GBG80259.1 - 0.19 8.8 4.6 0.25 8.4 4.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SDA1 PF05285.12 GBG80260.1 - 2.3 7.6 112.6 0.73 9.2 20.6 3.0 3 0 0 3 3 3 0 SDA1 Oberon_cc PF16312.5 GBG80261.1 - 1.1e-38 132.1 20.6 1.1e-38 132.1 20.6 1.9 2 0 0 2 2 2 1 Coiled-coil region of Oberon PHD_Oberon PF07227.11 GBG80261.1 - 2.1e-32 111.7 27.9 3.7e-32 110.9 27.9 1.4 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein DUF3915 PF13054.6 GBG80261.1 - 0.00053 20.0 7.1 0.00053 20.0 7.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) PRP38_assoc PF12871.7 GBG80261.1 - 0.012 16.3 14.5 0.012 16.3 14.5 3.4 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Exonuc_VII_L PF02601.15 GBG80261.1 - 0.82 9.2 9.6 1.5 8.3 9.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit YnfE PF17452.2 GBG80261.1 - 3.2 8.1 6.9 0.87 9.9 0.9 2.5 1 1 1 2 2 2 0 Uncharacterized YnfE-like Pex14_N PF04695.13 GBG80261.1 - 4.4 8.0 14.0 0.97 10.1 10.6 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RVT_1 PF00078.27 GBG80262.1 - 3.1e-30 105.3 0.1 4.8e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Miga PF10265.9 GBG80262.1 - 0.18 10.7 0.3 0.25 10.3 0.3 1.1 1 0 0 1 1 1 0 Mitoguardin RT_RNaseH_2 PF17919.1 GBG80263.1 - 1.2e-28 99.1 0.0 2.3e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80263.1 - 2.3e-22 79.3 0.0 5e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80263.1 - 2.3e-16 60.0 0.0 3.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG80263.1 - 6.3 6.0 31.3 10 5.3 31.3 1.3 1 0 0 1 1 1 0 BUD22 zf-CCHC PF00098.23 GBG80264.1 - 1.9e-06 27.7 3.0 3.2e-06 27.0 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle PASTA PF03793.19 GBG80264.1 - 0.018 14.9 0.1 0.018 14.9 0.1 2.4 4 0 0 4 4 4 0 PASTA domain zf-CCHC_2 PF13696.6 GBG80264.1 - 1.5 8.7 4.0 2.9 7.8 4.0 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG80265.1 - 1.3e-06 28.2 3.1 2.1e-06 27.5 3.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG80265.1 - 0.0035 17.0 0.5 0.0094 15.6 0.5 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG80265.1 - 0.011 15.6 3.0 0.019 14.7 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle RR_TM4-6 PF06459.12 GBG80265.1 - 5.4 6.8 13.6 6.8 6.4 13.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VIR_N PF15912.5 GBG80265.1 - 8.8 5.8 16.7 6 6.4 15.5 1.4 1 1 0 1 1 1 0 Virilizer, N-terminal CLP_protease PF00574.23 GBG80266.1 - 1.2e-67 227.3 0.2 1.7e-67 226.8 0.2 1.2 1 0 0 1 1 1 1 Clp protease Myb_DNA-bind_4 PF13837.6 GBG80267.1 - 1.8e-08 34.6 2.2 3.2e-08 33.8 2.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG80267.1 - 0.0059 16.8 0.2 0.014 15.6 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG80267.1 - 0.0084 16.2 2.1 0.016 15.3 2.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain JmjC PF02373.22 GBG80268.1 - 5.1e-43 146.1 0.2 8.2e-43 145.5 0.2 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 GBG80268.1 - 1.3e-16 60.3 1.6 2.5e-16 59.3 1.6 1.5 1 0 0 1 1 1 1 jmjN domain PAH PF02671.21 GBG80268.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Paired amphipathic helix repeat RVT_1 PF00078.27 GBG80269.1 - 3.8e-31 108.3 0.1 7.9e-31 107.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80269.1 - 3.6e-25 87.9 0.1 8.6e-25 86.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80269.1 - 1.1e-19 70.7 0.7 3.2e-19 69.1 0.7 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80269.1 - 3.6e-17 62.2 0.1 1.1e-16 60.7 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG80269.1 - 8.5e-17 61.5 0.0 2.8e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80269.1 - 0.00027 21.1 0.0 0.00079 19.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG80269.1 - 0.14 12.0 0.0 0.42 10.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain DUF5095 PF17016.5 GBG80269.1 - 0.15 11.8 0.2 0.29 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) zf-C5HC2 PF02928.16 GBG80270.1 - 4.7e-11 42.9 11.1 8.2e-11 42.1 11.1 1.4 1 0 0 1 1 1 1 C5HC2 zinc finger Flagellar_rod PF05149.12 GBG80270.1 - 0.044 13.2 1.8 0.071 12.6 1.8 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein zf-RanBP PF00641.18 GBG80271.1 - 1e-07 31.1 14.1 2.7e-05 23.4 1.6 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 GBG80271.1 - 0.012 15.7 3.3 0.66 10.1 0.1 2.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 GBG80271.1 - 0.056 12.8 7.2 0.28 10.6 2.2 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 GBG80271.1 - 0.63 10.1 9.0 8.8 6.4 9.1 2.5 1 1 0 1 1 1 0 Double zinc ribbon DUF3615 PF12274.8 GBG80271.1 - 2 9.0 3.9 2.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3615) OrfB_Zn_ribbon PF07282.11 GBG80271.1 - 4.1 7.4 5.6 12 6.0 1.2 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF3678 PF12435.8 GBG80271.1 - 7.5 6.0 5.8 27 4.2 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) AT_hook PF02178.19 GBG80272.1 - 0.2 11.6 5.4 0.23 11.4 1.7 2.5 2 0 0 2 2 2 0 AT hook motif Nop14 PF04147.12 GBG80274.1 - 0.039 12.2 21.2 0.046 11.9 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG80274.1 - 0.64 8.2 20.8 0.88 7.8 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG80274.1 - 1.6 8.0 24.6 2.1 7.7 24.6 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG80274.1 - 2.4 7.4 28.7 3.5 6.9 28.7 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG80274.1 - 2.9 7.4 14.5 4.1 6.9 14.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LRR_6 PF13516.6 GBG80275.1 - 3.8e-31 104.5 15.4 3.4e-06 26.7 0.1 7.0 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 GBG80275.1 - 2.3e-13 50.1 4.3 0.00029 21.2 0.2 4.3 3 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG80275.1 - 7.9e-09 34.9 5.5 3.9 8.4 0.1 6.0 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.6 GBG80275.1 - 2.6e-07 30.3 6.5 0.021 14.6 0.6 5.2 2 1 2 4 4 4 4 Leucine rich repeat SDA1 PF05285.12 GBG80276.1 - 0.12 11.8 18.8 0.14 11.5 18.8 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG80276.1 - 0.53 8.5 16.7 0.65 8.2 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG80276.1 - 0.56 8.4 21.1 0.74 8.0 21.1 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 GBG80276.1 - 1.5 7.9 3.3 2.1 7.5 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 GBG80276.1 - 1.9 6.5 20.2 2.4 6.1 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 GBG80276.1 - 1.9 8.5 22.6 2.7 8.0 22.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG80276.1 - 3.2 7.0 22.7 4.1 6.7 22.7 1.1 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.7 GBG80276.1 - 4.6 5.3 7.1 5.5 5.0 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 GBG80276.1 - 9.3 4.9 9.8 12 4.5 9.8 1.1 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG80277.1 - 3.3e-54 181.1 0.0 3.9e-28 97.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80277.1 - 6.7e-37 126.0 0.0 1.7e-21 76.4 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80277.1 - 6e-32 111.0 0.1 1.2e-31 109.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80277.1 - 0.019 14.7 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80277.1 - 0.02 15.5 0.0 0.047 14.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG80277.1 - 0.065 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG80278.1 - 0.00042 20.5 5.0 0.0011 19.2 0.1 3.4 2 1 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG80279.1 - 1.3e-10 41.5 0.0 2.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG80279.1 - 0.0003 21.1 0.0 0.00062 20.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80279.1 - 0.00091 19.2 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG80279.1 - 0.0018 18.0 0.0 0.0052 16.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG80279.1 - 0.0023 18.5 0.0 0.0049 17.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG80279.1 - 0.0036 17.6 0.1 0.012 16.0 0.1 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80279.1 - 0.0063 17.1 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG80280.1 - 1.9e-31 108.0 0.0 2.2e-16 59.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80280.1 - 3.9e-30 104.2 0.0 8.1e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80280.1 - 5.8e-26 91.4 0.0 1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80280.1 - 8e-16 57.9 0.2 3.5e-15 55.9 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG80280.1 - 1.5e-12 47.3 0.0 3e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG80280.1 - 7.7e-12 45.4 0.0 2.8e-11 43.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80280.1 - 6.8e-05 23.0 0.1 0.00016 21.8 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Med14 PF08638.11 GBG80281.1 - 0.0062 16.0 0.2 0.0071 15.8 0.2 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG16 PF08614.11 GBG80281.1 - 0.012 15.8 13.5 0.015 15.5 13.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 GBG80281.1 - 0.036 13.1 11.2 0.046 12.8 11.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_lysozyme2 PF18013.1 GBG80281.1 - 0.048 13.7 0.6 0.063 13.3 0.6 1.2 1 0 0 1 1 1 0 Phage tail lysozyme Lectin_N PF03954.14 GBG80281.1 - 0.066 12.9 5.1 0.59 9.9 4.2 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain CobU PF02283.16 GBG80281.1 - 0.069 12.7 3.4 0.087 12.4 3.4 1.1 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Filament PF00038.21 GBG80281.1 - 0.075 12.6 16.3 0.063 12.9 7.4 2.0 1 1 1 2 2 2 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 GBG80281.1 - 0.36 11.0 17.3 0.49 10.6 17.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 GBG80281.1 - 0.42 10.7 13.7 1.6 8.8 4.4 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 GBG80281.1 - 0.46 10.7 6.4 0.62 10.2 5.8 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family THOC7 PF05615.13 GBG80281.1 - 0.65 10.3 19.3 1 9.6 5.0 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 FlaC_arch PF05377.11 GBG80281.1 - 1.1 9.8 11.1 6.5 7.2 0.6 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) BST2 PF16716.5 GBG80281.1 - 1.1 9.9 12.4 18 6.0 1.7 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF724 PF05266.14 GBG80281.1 - 1.1 9.0 13.7 1.5 8.6 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HAUS5 PF14817.6 GBG80281.1 - 1.2 7.8 17.1 4.8 5.8 16.8 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 PRKG1_interact PF15898.5 GBG80281.1 - 1.8 9.5 17.0 0.77 10.7 13.9 1.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TMPIT PF07851.13 GBG80281.1 - 5 6.3 7.2 6.3 6.0 7.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 GBG80281.1 - 5.7 5.7 18.0 6.6 5.5 18.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 GBG80281.1 - 6.1 7.4 13.8 16 6.0 2.3 2.8 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 GBG80281.1 - 8.3 6.3 15.2 5.1 6.9 1.6 3.0 1 1 1 3 3 3 0 Septum formation initiator Efg1 PF10153.9 GBG80281.1 - 8.5 6.8 14.7 40 4.6 14.8 1.9 1 1 0 1 1 1 0 rRNA-processing protein Efg1 AAA_2 PF07724.14 GBG80282.1 - 1.9e-41 142.0 0.0 4.7e-33 114.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 GBG80282.1 - 1.6e-14 54.5 0.2 2.8e-06 27.8 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GBG80282.1 - 1.2e-07 31.8 0.1 2.1e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 GBG80282.1 - 5.7e-07 29.5 5.1 2.5e-06 27.5 0.3 2.8 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 GBG80282.1 - 3e-06 26.5 0.1 0.0009 18.4 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain AAA_22 PF13401.6 GBG80282.1 - 2.4e-05 24.6 0.2 0.00022 21.5 0.0 2.5 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 GBG80282.1 - 3.4e-05 23.3 0.1 0.0024 17.3 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 GBG80282.1 - 6.5e-05 23.4 0.7 0.00015 22.2 0.2 2.0 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 GBG80282.1 - 7e-05 22.2 0.1 0.00015 21.1 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 GBG80282.1 - 0.00032 20.5 0.8 0.0038 17.0 0.1 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 GBG80282.1 - 0.00064 19.1 0.2 0.0014 17.9 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 GBG80282.1 - 0.002 18.6 0.0 0.006 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GBG80282.1 - 0.0022 17.7 1.0 0.053 13.2 0.0 3.0 4 0 0 4 4 4 1 Sigma-54 interaction domain ABC_tran PF00005.27 GBG80282.1 - 0.0027 18.2 0.0 0.0087 16.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 GBG80282.1 - 0.0038 17.5 0.3 0.016 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GBG80282.1 - 0.0081 16.3 0.0 0.018 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 GBG80282.1 - 0.011 15.8 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 GBG80282.1 - 0.032 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 GBG80282.1 - 0.034 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 GBG80282.1 - 0.051 13.0 0.2 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 GBG80282.1 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 GBG80282.1 - 0.08 12.8 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein G-alpha PF00503.20 GBG80282.1 - 0.083 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit IstB_IS21 PF01695.17 GBG80282.1 - 0.093 12.5 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 GBG80282.1 - 0.097 12.7 0.6 6.7 6.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 GBG80282.1 - 0.18 11.5 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Dimer_Tnp_hAT PF05699.14 GBG80283.1 - 2.5e-05 24.0 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region VEGFR-2_TMD PF17988.1 GBG80285.1 - 0.11 11.9 0.5 0.2 11.1 0.5 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain RT_RNaseH_2 PF17919.1 GBG80286.1 - 3.1e-30 104.2 0.0 2.4e-29 101.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80286.1 - 3.2e-29 101.3 0.3 4.3e-28 97.7 0.1 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80286.1 - 1.9e-18 66.3 1.2 4.6e-18 65.1 1.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG80286.1 - 0.0001 22.4 0.2 0.00033 20.8 0.1 2.0 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 GBG80286.1 - 0.026 14.1 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3138 PF11336.8 GBG80286.1 - 0.5 8.9 2.5 0.77 8.3 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RVT_1 PF00078.27 GBG80287.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) gpUL132 PF11359.8 GBG80290.1 - 0.045 13.3 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Glycoprotein UL132 RVT_1 PF00078.27 GBG80291.1 - 4.1e-32 111.5 0.0 6.1e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80291.1 - 1.5e-18 66.7 0.0 4.9e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80291.1 - 1.1e-05 25.7 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG80293.1 - 2.6e-13 50.1 0.0 6.6e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-C2HE PF16278.5 GBG80293.1 - 0.038 14.4 0.5 0.14 12.6 0.5 2.0 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger RVT_1 PF00078.27 GBG80294.1 - 9.2e-96 319.6 1.3 6.4e-34 117.4 0.0 4.5 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80294.1 - 4.2e-87 286.6 0.0 3.5e-32 110.4 0.1 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80294.1 - 3.3e-72 239.5 0.1 3.4e-23 81.9 0.0 5.1 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80294.1 - 2e-49 165.5 14.6 1.2e-18 66.9 0.1 4.8 4 0 0 4 4 4 4 Integrase zinc binding domain rve PF00665.26 GBG80294.1 - 2.4e-26 92.3 0.0 5.4e-12 46.0 0.0 4.0 3 0 0 3 3 3 2 Integrase core domain zf-H2C2 PF09337.10 GBG80294.1 - 2.1e-07 31.1 0.0 1.7 8.9 0.0 4.0 3 0 0 3 3 3 3 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG80294.1 - 3e-05 24.2 0.5 0.038 14.3 0.0 3.6 2 0 0 2 2 2 2 Retrotransposon gag protein Chromo PF00385.24 GBG80294.1 - 6.6e-05 22.7 0.0 0.36 10.8 0.0 3.8 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG80294.1 - 0.00049 19.8 0.0 0.94 9.1 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1564) rve_3 PF13683.6 GBG80294.1 - 0.0053 16.5 0.0 5.7 6.8 0.0 3.1 2 0 0 2 2 2 2 Integrase core domain DUF4392 PF14336.6 GBG80294.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) gag-asp_proteas PF13975.6 GBG80297.1 - 2e-09 37.9 0.1 4.4e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG80297.1 - 2.1e-09 37.2 0.0 5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80297.1 - 1.7e-08 35.0 0.1 3.6e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80297.1 - 0.00069 19.4 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG80298.1 - 5.7e-26 90.5 0.0 1.5e-25 89.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80298.1 - 1.4e-24 86.4 0.0 3.7e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80298.1 - 1.5e-24 86.7 0.0 3.8e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG80298.1 - 6.5e-09 36.2 0.0 2.3e-08 34.5 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80298.1 - 2.7e-08 34.3 0.1 1e-07 32.5 0.0 2.1 2 0 0 2 2 1 1 Aspartyl protease RNA_polI_A34 PF08208.11 GBG80298.1 - 2.5e-06 27.7 20.6 2.5e-06 27.7 20.6 2.1 2 0 0 2 2 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Nop53 PF07767.11 GBG80298.1 - 2.1e-05 24.1 16.9 2.1e-05 24.1 16.9 2.7 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Asp_protease PF09668.10 GBG80298.1 - 0.0021 17.9 0.1 0.004 16.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RR_TM4-6 PF06459.12 GBG80298.1 - 0.0044 16.9 14.3 0.0044 16.9 14.3 3.4 4 0 0 4 4 3 1 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 GBG80298.1 - 0.005 17.0 11.3 0.005 17.0 11.3 3.9 5 0 0 5 5 4 1 Coiled-coil domain containing protein (DUF2052) Retrotrans_gag PF03732.17 GBG80298.1 - 0.0071 16.6 2.5 0.034 14.4 0.0 3.3 3 0 0 3 3 2 1 Retrotransposon gag protein RVP PF00077.20 GBG80298.1 - 0.014 15.7 0.0 0.047 14.0 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_5 PF14787.6 GBG80298.1 - 0.016 14.9 1.7 0.041 13.6 1.7 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG80298.1 - 0.69 10.1 4.6 2.1 8.5 4.6 1.9 1 0 0 1 1 1 0 Zinc knuckle SpoIIP PF07454.11 GBG80298.1 - 1.3 8.5 13.0 3.5 7.0 13.0 1.7 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SAPS PF04499.15 GBG80298.1 - 2.5 6.8 13.9 0.019 13.7 5.3 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein rve PF00665.26 GBG80299.1 - 4.4e-15 55.9 0.0 7.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HIP1_clath_bdg PF16515.5 GBG80299.1 - 0.42 11.3 6.2 0.77 10.4 5.7 1.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Integrase_H2C2 PF17921.1 GBG80300.1 - 3.9e-17 62.1 0.2 8e-17 61.1 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG80300.1 - 2e-14 53.8 1.6 4.8e-14 52.5 1.6 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80300.1 - 1.6e-07 31.3 0.3 3.7e-07 30.1 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG80300.1 - 0.0027 17.9 0.0 0.0069 16.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG80300.1 - 0.02 15.0 0.1 0.08 13.1 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain DUF3729 PF12526.8 GBG80300.1 - 4 9.0 8.3 12 7.5 8.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) RVT_1 PF00078.27 GBG80301.1 - 4.7e-35 121.1 0.3 2.4e-28 99.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80301.1 - 2e-20 73.0 0.0 4.8e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80301.1 - 6.1e-15 55.1 0.4 2.3e-14 53.2 0.4 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80301.1 - 9.2e-15 54.9 0.3 6.7e-10 39.2 0.0 3.2 3 0 0 3 3 3 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG80301.1 - 3.2e-14 52.8 0.0 8.3e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG80301.1 - 0.01 15.6 0.0 1.9 8.3 0.0 2.8 2 0 0 2 2 2 0 Integrase core domain Retrotrans_gag PF03732.17 GBG80301.1 - 0.096 13.0 0.0 0.48 10.7 0.0 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein GCN5L1 PF06320.13 GBG80301.1 - 1.9 8.6 5.6 5 7.3 5.6 1.7 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) RT_RNaseH_2 PF17919.1 GBG80302.1 - 1.9e-24 85.6 0.0 4.2e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80302.1 - 7.2e-22 77.7 0.0 1.4e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80302.1 - 1.4e-17 64.0 0.1 3.9e-16 59.2 0.1 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG80304.1 - 6.9e-11 42.1 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG80305.1 - 3.4e-05 23.5 0.0 5.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG80305.1 - 0.00031 20.6 0.0 0.00073 19.4 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 GBG80306.1 - 5.4e-09 35.9 0.0 9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DciA PF05258.12 GBG80306.1 - 0.043 14.2 0.0 23 5.5 0.0 2.8 2 0 0 2 2 2 0 Dna[CI] antecedent, DciA NTP_transf_2 PF01909.23 GBG80306.1 - 0.072 13.4 0.1 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Nucleotidyltransferase domain CLIP1_ZNF PF16641.5 GBG80306.1 - 0.079 12.9 4.7 3 7.8 0.2 2.5 2 0 0 2 2 2 0 CLIP1 zinc knuckle KAR9 PF08580.10 GBG80306.1 - 7.7 4.9 25.3 1.2 7.5 9.7 2.3 2 0 0 2 2 2 0 Yeast cortical protein KAR9 rve PF00665.26 GBG80307.1 - 1.6e-12 47.7 0.1 3.8e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG80307.1 - 3.7e-06 27.4 0.0 1.5e-05 25.4 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80307.1 - 0.00027 21.5 0.0 0.0009 19.8 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80307.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease EF-hand_1 PF00036.32 GBG80308.1 - 9.1e-23 78.1 0.0 1.7e-06 27.1 0.0 5.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 GBG80308.1 - 1.5e-18 65.0 0.7 0.00012 21.7 0.1 5.1 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 GBG80308.1 - 1.2e-16 60.9 0.5 8e-08 32.6 0.0 3.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG80308.1 - 5.4e-13 47.8 0.0 0.00025 20.4 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 GBG80308.1 - 6.3e-12 45.2 0.5 1.7e-05 24.5 0.0 4.2 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 GBG80308.1 - 1.1e-06 28.9 0.1 0.0021 18.3 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain Caleosin PF05042.13 GBG80308.1 - 0.003 17.5 0.2 1.1 9.2 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein Integrase_H2C2 PF17921.1 GBG80309.1 - 4.9e-14 52.2 2.0 9.1e-14 51.3 0.1 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG80309.1 - 5.2e-11 42.3 0.0 1.6e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG80309.1 - 1.5e-09 38.1 0.0 3.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80309.1 - 3.3e-06 27.2 0.0 7.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Nop14 PF04147.12 GBG80310.1 - 0.35 9.0 5.4 0.39 8.9 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG80310.1 - 9.5 4.4 7.2 12 4.0 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein WES_acyltransf PF03007.16 GBG80311.1 - 1.1 9.0 5.7 1.2 8.8 5.7 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain RT_RNaseH_2 PF17919.1 GBG80312.1 - 2.4e-31 107.7 0.0 6.1e-31 106.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80312.1 - 2.1e-30 105.1 0.0 6.1e-30 103.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Arc_PepC_II PF06847.11 GBG80312.1 - 0.59 10.7 3.9 93 3.6 1.2 4.3 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II Linker_histone PF00538.19 GBG80313.1 - 1.8e-18 66.6 0.3 1.8e-18 66.6 0.3 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family Linker_histone PF00538.19 GBG80314.1 - 3.3e-18 65.8 0.3 3.3e-18 65.8 0.3 2.9 3 0 0 3 3 3 1 linker histone H1 and H5 family MAP65_ASE1 PF03999.12 GBG80314.1 - 5.8 5.5 13.6 8.8 4.9 13.6 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RT_RNaseH_2 PF17919.1 GBG80315.1 - 1.3e-25 89.3 0.0 3.5e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80315.1 - 1.9e-23 82.7 0.0 5.1e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80315.1 - 5.8e-18 64.7 0.3 1.9e-17 63.1 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80315.1 - 3.9e-12 46.2 0.1 8e-10 38.6 0.0 2.4 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80315.1 - 2.8e-08 34.0 0.0 1e-07 32.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG80315.1 - 1.2e-06 29.0 0.0 4.5e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80315.1 - 2.2e-05 25.0 0.0 5.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80315.1 - 8.6e-05 22.3 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80315.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG80315.1 - 0.043 14.1 4.0 0.2 11.9 0.0 3.9 4 0 0 4 4 4 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG80315.1 - 0.095 12.9 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger CLZ PF16526.5 GBG80315.1 - 0.14 12.6 4.2 5 7.6 0.7 3.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 GBG80315.1 - 0.52 10.8 9.2 1.9 9.0 0.0 3.9 3 0 0 3 3 3 0 Cell division protein ZapB Plasmid_RAQPRD PF09686.10 GBG80316.1 - 0.091 13.0 0.9 0.28 11.4 0.9 1.8 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Virul_Fac PF10139.9 GBG80316.1 - 0.15 10.3 10.1 0.2 9.8 10.1 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor TED_complement PF07678.14 GBG80316.1 - 0.2 10.6 3.4 0.14 11.1 1.6 1.6 2 0 0 2 2 2 0 A-macroglobulin TED domain CAC1F_C PF16885.5 GBG80316.1 - 9.8 5.7 12.7 18 4.9 12.7 1.4 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term RT_RNaseH_2 PF17919.1 GBG80317.1 - 4.9e-26 90.7 0.0 2.2e-25 88.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80317.1 - 8.2e-24 83.9 0.0 2.8e-23 82.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80317.1 - 2e-22 79.8 0.1 3.7e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80317.1 - 1.4e-15 57.1 0.7 4e-15 55.7 0.7 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80317.1 - 1.1e-09 38.5 0.0 3.1e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG80317.1 - 0.008 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease ZapB PF06005.12 GBG80317.1 - 1.1 9.7 4.0 2.3 8.7 0.8 3.2 2 1 0 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 GBG80317.1 - 1.9 9.2 4.6 1.1 10.0 0.1 3.1 3 1 0 3 3 3 0 SlyX Sec8_exocyst PF04048.14 GBG80319.1 - 4.6e-28 97.9 0.6 1.4e-27 96.3 0.6 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 GBG80319.1 - 1e-10 41.4 0.3 2.3e-10 40.2 0.3 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Dor1 PF04124.12 GBG80319.1 - 0.088 11.5 1.0 0.14 10.8 1.0 1.3 1 0 0 1 1 1 0 Dor1-like family Zw10 PF06248.13 GBG80319.1 - 0.088 11.4 0.5 0.19 10.3 0.5 1.5 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Exonuc_VII_L PF02601.15 GBG80319.1 - 0.1 12.1 2.0 0.14 11.7 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Aminotran_3 PF00202.21 GBG80321.1 - 4e-47 160.8 0.0 2.4e-31 108.8 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 GBG80321.1 - 2.4e-11 43.8 0.0 1.7e-05 24.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain PDCD2_C PF04194.13 GBG80322.1 - 1.7e-32 112.9 0.1 1.7e-32 112.9 0.1 1.8 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Cys_rich_CPXG PF14255.6 GBG80322.1 - 0.16 11.9 1.5 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG MFS_1 PF07690.16 GBG80323.1 - 1.9e-28 99.4 25.0 2.7e-27 95.6 0.4 3.2 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GBG80323.1 - 1.9e-10 40.2 0.2 1.9e-10 40.2 0.2 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter VIT1 PF01988.19 GBG80323.1 - 7.7e-05 22.7 8.9 7.7e-05 22.7 8.9 3.6 4 1 0 4 4 4 1 VIT family OATP PF03137.20 GBG80323.1 - 0.0024 16.3 21.1 0.058 11.7 12.5 4.4 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family Na_trans_assoc PF06512.13 GBG80323.1 - 0.0058 16.9 3.2 0.41 10.9 0.0 3.0 3 0 0 3 3 3 1 Sodium ion transport-associated ATG22 PF11700.8 GBG80323.1 - 0.016 13.9 3.5 0.063 11.9 1.3 2.4 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like FAM176 PF14851.6 GBG80323.1 - 0.088 12.5 14.2 0.63 9.7 0.1 4.5 3 1 1 4 4 4 0 FAM176 family FHIPEP PF00771.20 GBG80323.1 - 0.23 9.9 1.0 4.3 5.7 0.3 2.8 3 0 0 3 3 3 0 FHIPEP family DUF4834 PF16118.5 GBG80323.1 - 3 8.9 10.1 62 4.6 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Nckap1 PF09735.9 GBG80324.1 - 5.3e-184 614.2 0.0 2.8e-78 264.1 0.0 4.3 4 1 0 4 4 4 4 Membrane-associated apoptosis protein Myc_N PF01056.18 GBG80324.1 - 0.013 15.4 0.2 0.013 15.4 0.2 2.4 2 0 0 2 2 2 0 Myc amino-terminal region GCIP PF13324.6 GBG80324.1 - 0.14 11.7 0.9 1.2 8.7 0.1 2.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting RskA PF10099.9 GBG80324.1 - 0.28 11.5 15.3 0.49 10.7 1.4 4.0 3 0 0 3 3 3 0 Anti-sigma-K factor rskA RVT_1 PF00078.27 GBG80326.1 - 1.1e-23 83.9 0.0 2.3e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80326.1 - 2.4e-12 46.7 0.0 8.9e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG80326.1 - 6e-07 30.0 0.0 1.7e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80326.1 - 2e-06 28.2 0.0 7.2e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80326.1 - 1.2e-05 25.1 0.0 3.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG80326.1 - 0.00052 20.3 0.0 0.0018 18.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG80326.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG80326.1 - 0.006 16.8 4.9 0.05 13.9 0.0 3.6 4 0 0 4 4 4 1 Retrotransposon gag protein DUF5645 PF18713.1 GBG80326.1 - 0.26 11.6 1.7 1 9.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5645) Histone_HNS PF00816.21 GBG80326.1 - 4.5 8.2 9.2 7.5 7.5 6.5 3.0 2 0 0 2 2 2 0 H-NS histone family Thioredoxin PF00085.20 GBG80327.1 - 4.4e-16 58.7 0.0 7.7e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG80327.1 - 2.3e-09 37.6 0.0 4.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GBG80327.1 - 1.4e-08 34.8 0.0 3.1e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GBG80327.1 - 2.8e-06 27.5 0.0 0.00014 22.1 0.1 2.3 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 GBG80327.1 - 0.0002 21.3 0.0 0.00052 19.9 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_4 PF13462.6 GBG80327.1 - 0.021 15.0 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 GBG80327.1 - 0.031 14.3 0.2 0.095 12.8 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_6 PF13848.6 GBG80327.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Use1 PF09753.9 GBG80328.1 - 0.0014 18.4 10.9 0.0019 18.0 10.9 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Plexin_cytopl PF08337.12 GBG80328.1 - 0.0079 14.9 3.1 0.011 14.5 3.1 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain PIEZO PF15917.5 GBG80328.1 - 0.32 10.4 6.4 0.49 9.8 6.4 1.2 1 0 0 1 1 1 0 Piezo DUF4288 PF14119.6 GBG80328.1 - 0.38 11.2 3.2 1 9.8 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) DUF3006 PF11213.8 GBG80328.1 - 4.9 7.5 6.1 4.3 7.6 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) CLZ PF16526.5 GBG80328.1 - 6.4 7.2 9.0 0.59 10.5 0.4 3.3 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Retrotrans_gag PF03732.17 GBG80329.1 - 0.034 14.4 0.2 0.07 13.4 0.2 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG80329.1 - 0.063 13.8 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ank_2 PF12796.7 GBG80330.1 - 1e-28 99.7 0.0 5.2e-09 36.6 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GBG80330.1 - 2.8e-17 62.3 0.7 0.014 15.8 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 GBG80330.1 - 9.9e-17 61.1 0.6 8.8e-06 26.2 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG80330.1 - 1.9e-16 59.9 5.6 0.0012 19.1 0.0 5.7 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG80330.1 - 3.3e-15 54.7 0.2 0.2 12.3 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat F-box-like PF12937.7 GBG80330.1 - 2.7e-06 27.2 0.0 6.5e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like p25-alpha PF05517.12 GBG80331.1 - 2.3e-32 112.3 0.0 3.7e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 p25-alpha zf-C3HC4_4 PF15227.6 GBG80331.1 - 1.8e-08 34.4 6.1 1.8e-08 34.4 6.1 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GBG80331.1 - 6.8e-08 32.4 4.9 2.2e-07 30.8 4.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GBG80331.1 - 5.2e-07 29.4 1.7 5.2e-07 29.4 1.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG80331.1 - 9.5e-06 25.4 3.7 2.8e-05 23.9 3.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG80331.1 - 6.1e-05 23.3 4.3 0.00019 21.7 4.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GBG80331.1 - 9.7e-05 22.2 4.3 0.00029 20.6 4.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG80331.1 - 0.00031 20.6 4.3 0.00031 20.6 4.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain EF-hand_7 PF13499.6 GBG80331.1 - 0.022 15.2 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 GBG80331.1 - 0.031 14.1 0.1 0.09 12.6 0.1 1.8 2 0 0 2 2 1 0 EF-hand domain pair zf-RING_10 PF16685.5 GBG80331.1 - 2 8.6 14.1 0.12 12.5 6.6 2.7 2 1 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 GBG80331.1 - 2.4 8.1 5.4 12 5.9 5.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DDE_Tnp_4 PF13359.6 GBG80332.1 - 5.8e-22 78.0 0.0 9.4e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80332.1 - 2.3e-15 56.8 0.0 3.6e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Dimer_Tnp_hAT PF05699.14 GBG80332.1 - 0.00028 20.6 0.2 0.00055 19.7 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG80333.1 - 2.5e-28 98.0 0.0 1.2e-26 92.6 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80333.1 - 4.8e-26 91.7 0.1 7.1e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80333.1 - 9.1e-26 90.2 0.0 2.6e-24 85.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HAND PF09110.11 GBG80333.1 - 0.022 15.5 4.2 0.044 14.5 4.2 1.5 1 0 0 1 1 1 0 HAND BUD22 PF09073.10 GBG80333.1 - 0.87 8.9 17.0 1.2 8.4 17.0 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GBG80333.1 - 7 6.3 14.0 11 5.7 14.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG80333.1 - 7.1 4.7 15.3 9.8 4.2 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG80333.1 - 7.5 5.9 15.2 10 5.4 15.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG80333.1 - 7.6 4.7 13.6 11 4.2 13.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Integrase_H2C2 PF17921.1 GBG80335.1 - 6.6e-17 61.4 0.2 1.3e-16 60.5 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80335.1 - 1e-10 41.8 0.0 1.4e-09 38.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG80335.1 - 1.8e-07 31.0 0.0 3.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80335.1 - 0.00063 20.3 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80335.1 - 0.0023 18.5 0.0 0.0052 17.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG80336.1 - 7.6e-26 90.1 0.0 2.6e-25 88.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80336.1 - 6.8e-23 81.0 0.0 2.1e-22 79.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80336.1 - 5.8e-19 68.5 0.1 1.4e-18 67.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80336.1 - 7.9e-19 67.5 0.2 2.4e-18 66.0 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80336.1 - 1.7e-08 34.7 0.0 5.1e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG80336.1 - 9e-08 32.7 0.0 2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80336.1 - 4.1e-07 30.5 0.0 1.1e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80336.1 - 4.6e-06 26.4 0.0 8.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG80336.1 - 0.00012 21.9 0.2 0.00075 19.4 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG80336.1 - 0.00056 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG80336.1 - 0.0043 17.2 0.1 0.012 15.9 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG80336.1 - 0.011 16.0 3.3 0.076 13.3 0.2 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein UPF0184 PF03670.13 GBG80336.1 - 0.65 10.4 2.0 1.3 9.4 0.0 2.6 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0184) FDF PF09532.10 GBG80336.1 - 1.6 9.7 4.3 5.2 8.0 4.3 1.9 1 0 0 1 1 1 0 FDF domain DUF572 PF04502.13 GBG80336.1 - 9.5 5.7 14.6 19 4.7 14.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) EF-hand_5 PF13202.6 GBG80337.1 - 1.4e-10 40.2 14.0 2.3e-05 23.7 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GBG80337.1 - 8.3e-10 37.8 16.2 9e-05 22.1 0.1 4.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 GBG80337.1 - 7.1e-09 34.6 26.5 4.9e-05 22.6 0.0 5.3 6 1 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 GBG80337.1 - 1.2e-08 35.2 3.5 6.6e-05 23.3 0.4 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 GBG80337.1 - 2.5e-05 24.0 12.7 0.1 12.5 0.1 5.2 4 1 1 5 5 5 2 EF-hand domain pair TPX2_importin PF12214.8 GBG80337.1 - 0.028 14.6 4.5 0.057 13.6 4.5 1.4 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein EF-hand_4 PF12763.7 GBG80337.1 - 0.15 12.0 0.5 2.5 8.1 0.0 2.7 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand E2F_CC-MB PF16421.5 GBG80337.1 - 0.33 11.3 2.4 1.1 9.7 2.4 1.8 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain BSP_II PF05432.11 GBG80337.1 - 0.49 10.1 22.4 0.21 11.2 9.6 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DivIC PF04977.15 GBG80337.1 - 0.73 9.6 2.8 1.8 8.4 2.8 1.6 1 0 0 1 1 1 0 Septum formation initiator RVT_1 PF00078.27 GBG80338.1 - 4.9e-27 94.9 0.1 7.7e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80338.1 - 5.1e-26 90.6 0.0 1.4e-25 89.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80338.1 - 2e-22 79.5 0.0 4.6e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80338.1 - 1.3e-15 57.2 0.9 3.1e-15 56.0 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80338.1 - 8.8e-10 38.8 0.0 2.5e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG80338.1 - 0.0049 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease p25-alpha PF05517.12 GBG80339.1 - 4.2e-14 53.0 2.2 8.7e-14 52.0 2.2 1.5 1 0 0 1 1 1 1 p25-alpha Retrotrans_gag PF03732.17 GBG80339.1 - 0.0027 18.0 4.4 0.13 12.6 0.0 3.8 4 0 0 4 4 4 2 Retrotransposon gag protein WDCP PF15390.6 GBG80339.1 - 1.2 7.4 4.6 1.8 6.8 4.6 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family gag-asp_proteas PF13975.6 GBG80341.1 - 9e-06 26.2 0.0 3.1e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80341.1 - 4e-05 24.2 0.0 0.00013 22.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80341.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG80341.1 - 0.0082 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG80341.1 - 0.031 13.9 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like cNMP_binding PF00027.29 GBG80341.1 - 0.13 12.4 0.0 0.48 10.5 0.0 2.0 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain TPM_phosphatase PF04536.14 GBG80342.1 - 3.5e-19 69.2 0.2 5.6e-19 68.5 0.2 1.3 1 0 0 1 1 1 1 TPM domain MFS_1 PF07690.16 GBG80343.1 - 1.5e-25 89.9 32.7 1.8e-25 89.6 28.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GBG80343.1 - 0.12 11.2 10.1 0.083 11.7 3.1 2.7 2 1 0 2 2 2 0 MFS_1 like family Myb_DNA-bind_4 PF13837.6 GBG80344.1 - 0.00015 22.1 0.3 0.00027 21.2 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Ac81 PF05820.11 GBG80344.1 - 1.5 8.3 3.0 2.4 7.7 3.0 1.2 1 0 0 1 1 1 0 Baculoviridae AC81 Toxin_8 PF07365.12 GBG80344.1 - 6.2 7.1 7.9 7 6.9 0.8 3.9 4 0 0 4 4 4 0 Alpha conotoxin precursor ESSS PF10183.9 GBG80345.1 - 0.0053 17.0 1.6 0.044 14.0 0.2 2.6 2 1 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Translin PF01997.16 GBG80346.1 - 1.2e-45 156.0 0.2 1.8e-45 155.5 0.2 1.2 1 0 0 1 1 1 1 Translin family MFS_1 PF07690.16 GBG80346.1 - 2.1e-25 89.4 31.7 9.5e-25 87.3 28.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SDA1 PF05285.12 GBG80346.1 - 0.00011 21.8 19.5 0.00017 21.2 19.5 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG80346.1 - 0.00042 18.7 24.7 0.00071 17.9 24.7 1.3 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 GBG80346.1 - 0.0015 18.0 21.6 0.0015 18.0 21.6 1.6 2 0 0 2 2 2 1 BUD22 CDC45 PF02724.14 GBG80346.1 - 0.024 12.9 14.9 0.039 12.3 14.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG80346.1 - 0.034 13.9 17.9 0.06 13.1 17.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SpoIIIAH PF12685.7 GBG80346.1 - 0.061 13.1 6.2 0.11 12.3 6.2 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein YL1 PF05764.13 GBG80346.1 - 0.077 13.1 19.3 0.14 12.3 19.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein SAPS PF04499.15 GBG80346.1 - 0.086 11.6 3.1 0.13 11.1 3.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 GBG80346.1 - 0.13 11.0 4.9 0.3 9.8 4.9 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Na_trans_assoc PF06512.13 GBG80346.1 - 0.22 11.8 12.3 0.47 10.7 12.3 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Zip PF02535.22 GBG80346.1 - 0.89 8.7 4.3 2.1 7.5 4.3 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.14 GBG80346.1 - 0.97 9.9 4.2 3.1 8.2 4.2 1.8 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mpp10 PF04006.12 GBG80346.1 - 1.1 7.6 27.7 1.8 6.9 27.7 1.2 1 0 0 1 1 1 0 Mpp10 protein TFIIA PF03153.13 GBG80346.1 - 2.1 8.2 19.0 4.2 7.3 19.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2530 PF10745.9 GBG80346.1 - 2.9 8.2 5.2 1.8 8.8 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) SURF2 PF05477.11 GBG80346.1 - 3.3 7.4 10.4 5.9 6.5 10.4 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Afi1 PF07792.12 GBG80346.1 - 6.5 7.2 15.0 14 6.2 15.0 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 GBG80346.1 - 7.2 5.3 6.6 14 4.3 6.6 1.4 1 0 0 1 1 1 0 Presenilin Myb_DNA-bind_4 PF13837.6 GBG80347.1 - 2.9e-09 37.2 0.8 2.9e-09 37.2 0.8 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG80347.1 - 0.013 15.8 0.3 0.013 15.8 0.3 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PriCT_1 PF08708.11 GBG80347.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) RVT_1 PF00078.27 GBG80349.1 - 3e-29 102.1 0.0 5e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG80349.1 - 3.4e-29 102.0 0.0 6.6e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG80349.1 - 3e-27 95.6 0.0 5.9e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG80349.1 - 0.14 12.0 1.3 3.4 7.5 0.1 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family PIP49_C PF12260.8 GBG80349.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 GCN5L1 PF06320.13 GBG80349.1 - 0.36 11.0 5.5 0.31 11.2 3.2 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) YabA PF06156.13 GBG80349.1 - 0.69 10.6 2.4 1.2 9.8 0.0 2.5 3 0 0 3 3 3 0 Initiation control protein YabA Ferritin PF00210.24 GBG80349.1 - 0.82 9.6 5.2 6.5 6.7 0.1 3.1 2 1 1 3 3 3 0 Ferritin-like domain ALIX_LYPXL_bnd PF13949.6 GBG80349.1 - 4.6 6.4 8.1 0.45 9.7 2.9 1.8 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Wzy_C PF04932.15 GBG80350.1 - 0.066 12.9 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 O-Antigen ligase Amnionless PF14828.6 GBG80350.1 - 0.11 11.3 3.5 0.15 10.9 3.5 1.2 1 0 0 1 1 1 0 Amnionless GWT1 PF06423.12 GBG80350.1 - 0.68 10.0 10.1 1 9.4 10.1 1.3 1 0 0 1 1 1 0 GWT1 Integrase_H2C2 PF17921.1 GBG80351.1 - 3.7e-18 65.4 0.3 8.1e-18 64.3 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80351.1 - 1.2e-09 38.3 0.0 3.1e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG80351.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG80351.1 - 0.025 14.8 0.1 0.051 13.8 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG80352.1 - 1e-24 86.8 0.0 2.9e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80352.1 - 3.2e-24 84.9 0.0 8.8e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80352.1 - 4.2e-20 72.2 0.0 1.2e-19 70.7 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80352.1 - 1.1e-08 35.3 0.0 6.6e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG80352.1 - 0.0009 19.5 0.2 0.025 14.8 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG80352.1 - 0.023 14.4 1.0 0.023 14.4 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Fib_alpha PF08702.10 GBG80352.1 - 10 6.3 8.1 36 4.5 0.1 3.2 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family RT_RNaseH PF17917.1 GBG80353.1 - 8.2e-25 87.1 0.0 2.3e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80353.1 - 2.5e-24 85.2 0.0 7e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80353.1 - 3.5e-20 72.5 0.0 9.5e-20 71.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG80353.1 - 0.00066 19.9 0.3 0.02 15.1 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG80353.1 - 0.019 14.7 1.0 0.019 14.7 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) RVT_1 PF00078.27 GBG80354.1 - 2.8e-27 95.7 0.8 4.9e-27 94.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80354.1 - 9.9e-07 29.3 0.0 9.6e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80354.1 - 6.8e-05 23.4 0.0 0.00021 21.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80354.1 - 7.5e-05 22.5 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG80354.1 - 0.0003 21.0 3.9 0.059 13.6 0.1 3.7 3 0 0 3 3 3 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG80354.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease ODV-E18 PF10717.9 GBG80355.1 - 0.0048 16.7 0.1 0.093 12.6 0.1 2.1 2 0 0 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 DUF3357 PF11837.8 GBG80355.1 - 1.1 9.7 5.6 0.89 10.0 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Marek_A PF02124.15 GBG80355.1 - 1.2 8.9 11.6 0.51 10.1 3.3 2.2 2 1 0 2 2 2 0 Marek's disease glycoprotein A DUF4448 PF14610.6 GBG80355.1 - 3.2 7.5 5.1 10 5.8 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Asparaginase_2 PF01112.18 GBG80357.1 - 2.1e-32 112.4 10.2 4.4e-13 48.9 0.3 5.2 5 0 0 5 5 5 5 Asparaginase TPR_2 PF07719.17 GBG80358.1 - 3.3e-12 45.5 0.8 0.02 15.0 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG80358.1 - 1.1e-11 44.0 0.2 0.0019 18.3 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG80358.1 - 4.6e-11 42.0 1.0 0.0079 16.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG80358.1 - 1.6e-08 34.3 0.3 0.0076 16.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG80358.1 - 1.2e-06 29.0 0.0 0.18 12.5 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG80358.1 - 2.2e-05 24.6 0.2 0.19 12.0 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG80358.1 - 0.00077 19.6 0.0 4.5 7.5 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG80358.1 - 0.0031 17.2 1.0 3.1 7.6 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 GBG80358.1 - 0.006 17.1 0.4 0.49 10.9 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG80358.1 - 0.097 12.6 0.6 14 5.7 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG80358.1 - 0.1 12.6 0.1 12 6.2 0.0 3.4 3 1 0 4 4 4 0 Tetratricopeptide repeat RT_RNaseH PF17917.1 GBG80359.1 - 2.8e-20 72.5 0.3 1.9e-19 69.9 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80359.1 - 2.2e-15 56.5 0.0 5.9e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG80359.1 - 0.0082 16.0 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG80359.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG80359.1 - 0.16 12.2 0.1 0.16 12.2 0.1 3.2 5 0 0 5 5 5 0 Retrotransposon gag protein CENP-K PF11802.8 GBG80359.1 - 0.46 10.0 4.0 0.96 9.0 4.0 1.6 1 0 0 1 1 1 0 Centromere-associated protein K Mt_ATP-synt_B PF05405.14 GBG80359.1 - 4.9 6.8 7.3 11 5.6 7.3 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RVT_1 PF00078.27 GBG80360.1 - 6.3e-18 65.1 0.1 1.1e-17 64.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_14 PF13428.6 GBG80360.1 - 0.0012 19.5 0.1 1.1 10.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG80360.1 - 0.0017 18.1 0.6 0.11 12.4 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG80360.1 - 0.009 16.1 0.7 2.1 8.7 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 GBG80360.1 - 0.039 13.2 0.1 0.073 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG80360.1 - 0.052 13.8 0.0 22 5.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG80360.1 - 0.15 12.4 0.3 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 GBG80361.1 - 9.7e-13 49.2 4.8 9.7e-13 49.2 4.8 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG80361.1 - 5.4e-05 23.0 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG80361.1 - 0.00013 21.3 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GBG80361.1 - 0.068 12.9 0.0 8.6 6.0 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 GBG80361.1 - 0.096 12.8 0.0 1.9 8.6 0.1 2.4 1 1 1 2 2 2 0 Thioesterase domain DUF659 PF04937.15 GBG80364.1 - 5.3e-19 68.6 0.0 9.2e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80364.1 - 0.00011 21.9 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 GBG80365.1 - 5.9e-43 147.1 0.0 1.2e-42 146.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG80365.1 - 1.4e-42 145.8 0.0 3.4e-42 144.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 GBG80365.1 - 3.5e-07 29.9 0.3 7e-07 28.9 0.3 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 GBG80365.1 - 9.2e-06 25.5 1.7 1.2 9.9 0.7 3.9 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_4 PF12799.7 GBG80365.1 - 6.7e-05 23.2 0.4 0.00072 19.9 1.5 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Malectin PF11721.8 GBG80365.1 - 0.00059 20.0 0.0 0.0048 17.0 0.0 2.2 2 0 0 2 2 2 1 Malectin domain Malectin_like PF12819.7 GBG80365.1 - 0.0043 16.3 0.0 0.31 10.2 0.0 2.6 3 0 0 3 3 3 1 Malectin-like domain DUF4360 PF14273.6 GBG80367.1 - 2.1e-29 102.7 0.0 2.6e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF1295 PF06966.12 GBG80369.1 - 5.8e-61 206.0 2.0 8.6e-61 205.4 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 GBG80369.1 - 0.0011 19.3 0.2 0.0042 17.5 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 GBG80369.1 - 0.0032 17.5 0.2 0.0059 16.6 0.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 GBG80369.1 - 0.0094 14.8 2.8 0.044 12.5 2.8 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 GBG80369.1 - 0.083 13.3 1.8 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase SelK_SelG PF10961.8 GBG80370.1 - 1.1 10.0 18.6 5 7.8 13.9 2.2 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Presenilin PF01080.17 GBG80370.1 - 2.7 6.7 11.7 3 6.5 11.7 1.0 1 0 0 1 1 1 0 Presenilin MDM1 PF15501.6 GBG80370.1 - 4.1 6.4 20.7 4.9 6.2 20.7 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 tRNA_synt_1c_R2 PF04557.15 GBG80370.1 - 4.3 8.3 15.3 1 10.3 6.2 2.0 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 EIIBC-GUT_N PF03612.14 GBG80370.1 - 4.5 7.0 8.8 2.5 7.8 3.2 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FRQ PF09421.10 GBG80370.1 - 5.1 5.0 7.9 6.1 4.7 7.9 1.0 1 0 0 1 1 1 0 Frequency clock protein BUD22 PF09073.10 GBG80370.1 - 9.3 5.5 26.2 11 5.2 26.2 1.0 1 0 0 1 1 1 0 BUD22 DUF3402 PF11882.8 GBG80370.1 - 9.8 5.2 9.3 12 4.8 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) CCSAP PF15748.5 GBG80370.1 - 9.8 6.3 15.6 14 5.8 15.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Nop14 PF04147.12 GBG80372.1 - 0.032 12.4 46.8 0.044 12.0 46.8 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG80372.1 - 0.4 10.1 44.1 0.4 10.1 44.1 1.2 1 0 0 1 1 1 0 SDA1 DUF4045 PF13254.6 GBG80372.1 - 3.4 7.2 14.6 3.6 7.1 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BUD22 PF09073.10 GBG80372.1 - 7.7 5.7 39.5 7.7 5.7 39.5 1.2 1 0 0 1 1 1 0 BUD22 MCM_bind PF09739.9 GBG80372.1 - 8.5 4.7 11.3 11 4.4 11.3 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Nop14 PF04147.12 GBG80373.1 - 2.7 6.1 17.7 2.8 6.0 17.7 1.0 1 0 0 1 1 1 0 Nop14-like family Ribosomal_60s PF00428.19 GBG80374.1 - 0.024 15.2 0.5 0.024 15.2 0.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein UPF0184 PF03670.13 GBG80374.1 - 0.062 13.7 0.6 0.19 12.1 0.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Macoilin PF09726.9 GBG80374.1 - 0.069 11.7 18.2 0.12 10.9 18.2 1.3 1 0 0 1 1 1 0 Macoilin family DUF1840 PF08895.11 GBG80374.1 - 4.2 7.8 14.8 0.47 10.8 8.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) DAG_kinase_N PF14513.6 GBG80374.1 - 4.7 7.4 8.8 0.12 12.6 1.2 2.2 2 1 0 2 2 2 0 Diacylglycerol kinase N-terminus DASH_Dad2 PF08654.10 GBG80374.1 - 5.4 7.5 15.0 2.2 8.8 1.4 3.4 4 1 0 4 4 4 0 DASH complex subunit Dad2 RT_RNaseH_2 PF17919.1 GBG80375.1 - 1.4e-33 114.9 0.0 3.6e-33 113.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80375.1 - 2.9e-27 95.0 0.2 1.1e-26 93.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80375.1 - 2.2e-26 92.7 0.1 4e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80375.1 - 1.3e-16 60.4 0.6 3e-16 59.3 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Vir_act_alpha_C PF10400.9 GBG80375.1 - 1.6 9.4 4.8 5.7 7.7 4.8 1.9 1 0 0 1 1 1 0 Virulence activator alpha C-term Exonuc_VII_L PF02601.15 GBG80375.1 - 3.4 7.1 6.8 7.1 6.1 6.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DDE_Tnp_4 PF13359.6 GBG80376.1 - 9.6e-20 70.8 0.0 2.8e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80376.1 - 7.5e-13 48.6 0.0 2.4e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 Plant transposon protein Golgin_A5 PF09787.9 GBG80376.1 - 0.05 13.1 0.3 0.088 12.3 0.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 KELK PF15796.5 GBG80376.1 - 0.27 11.7 1.8 0.46 11.0 0.3 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Myb_DNA-bind_4 PF13837.6 GBG80377.1 - 4.2e-09 36.7 4.1 6.8e-09 36.0 4.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG80377.1 - 0.8 9.9 2.6 1 9.6 1.7 1.7 1 1 1 2 2 2 0 Myb-like DNA-binding domain Rab3-GTPase_cat PF13890.6 GBG80378.1 - 0.16 11.6 6.8 0.071 12.7 1.1 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit DUF668 PF05003.12 GBG80378.1 - 0.64 10.5 4.4 0.33 11.4 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF668) LMBR1 PF04791.16 GBG80378.1 - 9.3 5.0 8.0 11 4.8 8.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Rhodanese PF00581.20 GBG80379.1 - 2.9e-07 31.0 0.0 6.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Phage_holin_7_1 PF16081.5 GBG80379.1 - 0.04 14.1 0.2 0.04 14.1 0.2 3.0 3 0 0 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Nucleotid_trans PF03407.16 GBG80380.1 - 7.9e-48 163.2 0.0 1.5e-47 162.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase SURF6 PF04935.12 GBG80380.1 - 1.9e-28 99.6 57.1 8e-28 97.6 30.6 3.2 2 1 1 3 3 3 2 Surfeit locus protein 6 RRP14 PF15459.6 GBG80380.1 - 4e-16 59.4 4.4 4e-16 59.4 4.4 4.9 5 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 Bax1-I PF01027.20 GBG80382.1 - 5.2e-33 114.6 17.0 6.3e-33 114.3 17.0 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Cnn_1N PF07989.11 GBG80383.1 - 0.0032 17.6 1.5 0.0032 17.6 1.5 12.0 8 4 7 15 15 15 1 Centrosomin N-terminal motif 1 Yae1_N PF09811.9 GBG80383.1 - 0.0051 16.5 4.2 0.016 14.9 4.2 1.9 1 0 0 1 1 1 1 Essential protein Yae1, N terminal OMP_b-brl_2 PF13568.6 GBG80383.1 - 0.87 9.6 4.4 4.9 7.1 5.0 2.0 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain Myb_DNA-bind_4 PF13837.6 GBG80384.1 - 6.7e-11 42.4 0.4 6.7e-11 42.4 0.4 2.4 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG80384.1 - 0.099 13.0 3.0 0.25 11.7 0.2 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AbiJ_NTD4 PF18863.1 GBG80384.1 - 0.12 12.8 0.8 0.21 12.1 0.4 1.5 2 0 0 2 2 2 0 AbiJ N-terminal domain 4 PEGSRP PF07623.11 GBG80385.1 - 1.6 8.6 5.1 90 3.0 1.8 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1584) Hydrolase PF00702.26 GBG80388.1 - 0.031 14.6 0.0 0.15 12.3 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1350 PF07082.11 GBG80389.1 - 1.5e-55 188.2 0.2 1.6e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1350) CENP-F_leu_zip PF10473.9 GBG80390.1 - 0.019 15.0 20.9 0.02 14.9 17.3 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dimer_Tnp_hAT PF05699.14 GBG80393.1 - 0.00041 20.1 0.1 0.00075 19.2 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG80394.1 - 3.4e-28 98.7 0.0 4.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.23 GBG80394.1 - 0.027 14.4 0.0 0.027 14.4 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family RVT_1 PF00078.27 GBG80397.1 - 4.9e-20 72.0 0.0 7.9e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG80399.1 - 6.8e-26 91.2 0.0 9.5e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG80400.1 - 4.6e-10 39.4 1.5 6.6e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG80400.1 - 0.00036 20.4 0.0 0.00097 19.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 GBG80403.1 - 9.4e-39 133.2 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG80403.1 - 0.0011 18.5 1.5 0.0023 17.5 1.5 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CobU PF02283.16 GBG80403.1 - 0.041 13.5 0.7 0.097 12.2 0.7 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Integrase_H2C2 PF17921.1 GBG80404.1 - 4.9e-33 113.0 2.1 1.8e-17 63.2 0.6 3.6 3 0 0 3 3 3 2 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG80404.1 - 6.5e-24 83.9 0.0 1.5e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80404.1 - 1.4e-23 83.1 0.0 1.2e-22 80.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG80404.1 - 0.00017 21.7 0.3 0.24 11.7 0.0 2.7 2 0 0 2 2 2 2 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG80404.1 - 0.019 15.5 0.0 0.053 14.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease BLOC1_2 PF10046.9 GBG80404.1 - 0.41 11.0 7.1 0.16 12.3 3.7 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Retrotrans_gag PF03732.17 GBG80404.1 - 1 9.7 6.4 0.78 10.1 0.2 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein DivIC PF04977.15 GBG80404.1 - 2.8 7.8 9.1 1.1 9.1 4.5 2.6 2 0 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 GBG80404.1 - 7.4 7.1 5.6 23 5.6 1.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sybindin PF04099.12 GBG80405.1 - 2.4e-49 167.0 0.0 2.8e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 GBG80405.1 - 2e-06 27.9 0.0 2.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RVT_1 PF00078.27 GBG80406.1 - 1.4e-25 90.1 0.0 1.7e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80406.1 - 0.096 13.3 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG80406.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG80406.1 - 0.15 12.7 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG80407.1 - 7.5e-18 64.4 0.0 1.3e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80407.1 - 2e-08 34.5 0.0 5.1e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4407 PF14362.6 GBG80407.1 - 4.6 6.5 5.6 6.1 6.1 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Complex1_49kDa PF00346.19 GBG80408.1 - 2e-46 158.3 0.0 6e-46 156.7 0.0 1.8 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RT_RNaseH_2 PF17919.1 GBG80408.1 - 4.8e-45 151.7 0.0 4.6e-24 84.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80408.1 - 4.4e-31 107.3 0.0 1.9e-20 73.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Peptidase_S8 PF00082.22 GBG80408.1 - 3e-30 105.5 0.4 3.4e-22 79.1 0.4 2.4 2 0 0 2 2 2 2 Subtilase family RVT_1 PF00078.27 GBG80408.1 - 2.5e-10 40.3 0.1 3.1e-08 33.4 0.1 2.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80408.1 - 0.023 15.3 0.1 0.11 13.2 0.1 2.1 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG80408.1 - 0.025 15.1 0.0 0.077 13.6 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG80408.1 - 0.038 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease TMEM51 PF15345.6 GBG80408.1 - 2.1 8.1 6.0 4.4 7.1 6.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 CCDC92 PF14916.6 GBG80408.1 - 4.1 7.3 5.6 8.5 6.2 0.2 3.3 2 1 1 3 3 3 0 Coiled-coil domain of unknown function RVT_1 PF00078.27 GBG80409.1 - 4e-28 98.4 0.1 6.8e-28 97.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80409.1 - 5.4e-17 61.7 0.0 1.5e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80409.1 - 7.7e-05 22.9 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5095 PF17016.5 GBG80409.1 - 0.2 11.3 0.3 0.34 10.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Spectrin PF00435.21 GBG80409.1 - 6.5 7.3 7.6 5.9 7.4 0.9 3.4 3 1 0 3 3 3 0 Spectrin repeat RT_RNaseH_2 PF17919.1 GBG80410.1 - 2.9e-54 181.3 0.1 3.4e-29 100.8 0.1 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80410.1 - 2.8e-40 136.8 0.0 6.6e-20 71.4 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80410.1 - 3.6e-24 85.5 0.1 5.4e-23 81.7 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80410.1 - 2e-14 53.4 0.1 4.9e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80410.1 - 4e-08 33.5 0.5 6.1e-05 23.2 0.0 3.0 2 0 0 2 2 2 2 Integrase core domain RVP_2 PF08284.11 GBG80410.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG80410.1 - 0.0045 16.9 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 GBG80410.1 - 0.011 16.3 0.0 0.036 14.6 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG80410.1 - 0.66 10.3 12.8 23 5.3 0.1 5.3 5 0 0 5 5 5 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG80411.1 - 1e-26 92.9 0.0 2.9e-26 91.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80411.1 - 3.3e-24 85.2 0.0 8.8e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80411.1 - 6.6e-19 68.3 0.0 1.3e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG80411.1 - 0.00034 20.8 0.7 0.002 18.4 0.3 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG80411.1 - 0.21 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease CsgE PF10627.9 GBG80411.1 - 4 7.7 6.4 9.3 6.5 6.4 1.7 1 0 0 1 1 1 0 Curli assembly protein CsgE TraG_N PF07916.11 GBG80411.1 - 7.2 5.3 5.6 14 4.4 5.6 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF4139 PF13598.6 GBG80413.1 - 0.36 10.5 10.4 1.6 8.4 2.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4139) RVT_1 PF00078.27 GBG80415.1 - 5.5e-28 98.0 0.0 8.2e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80415.1 - 7.4e-10 39.1 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG80415.1 - 2.1e-05 24.5 0.2 9e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain DUF5053 PF16476.5 GBG80415.1 - 0.15 11.7 0.0 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) Retrotrans_gag PF03732.17 GBG80416.1 - 0.097 13.0 2.1 0.38 11.1 0.0 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein rve PF00665.26 GBG80417.1 - 5e-28 97.7 0.2 2.6e-14 53.4 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG80417.1 - 3.6e-27 95.3 0.1 6.5e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80417.1 - 1.1e-25 89.5 0.0 2.4e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80417.1 - 2.3e-17 62.8 0.2 7.5e-17 61.2 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG80417.1 - 2e-12 47.3 0.0 4.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG80417.1 - 0.051 13.4 0.2 3.8 7.4 0.1 2.9 2 0 0 2 2 2 0 Integrase core domain PUF PF00806.19 GBG80417.1 - 0.11 12.2 0.1 14 5.6 0.0 2.8 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Retrotrans_gag PF03732.17 GBG80418.1 - 0.028 14.7 0.4 0.1 12.9 0.2 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein Rx_N PF18052.1 GBG80418.1 - 0.081 13.2 0.2 6.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Rx N-terminal domain DUF1664 PF07889.12 GBG80418.1 - 0.097 12.7 0.8 1.5 8.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) rve PF00665.26 GBG80419.1 - 4.1e-16 59.2 0.0 9e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG80419.1 - 5.1e-08 32.9 0.0 1.6e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80419.1 - 2.5e-05 24.5 0.0 6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CCD48 PF15799.5 GBG80419.1 - 0.0012 17.2 3.8 0.0018 16.7 3.8 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 HALZ PF02183.18 GBG80419.1 - 0.043 14.0 1.8 0.14 12.4 1.8 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2385 PF09539.10 GBG80419.1 - 0.055 14.0 0.2 1.1 9.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) CASP_C PF08172.12 GBG80419.1 - 0.095 12.0 1.0 0.3 10.4 0.2 2.1 2 0 0 2 2 2 0 CASP C terminal bZIP_2 PF07716.15 GBG80419.1 - 0.095 12.8 2.4 0.3 11.2 2.4 1.9 1 0 0 1 1 1 0 Basic region leucine zipper GIT_CC PF16559.5 GBG80419.1 - 0.29 11.0 2.0 0.84 9.6 2.0 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 GBG80419.1 - 0.31 11.2 5.5 0.11 12.6 1.7 2.2 2 0 0 2 2 2 0 bZIP transcription factor Retrotrans_gag PF03732.17 GBG80420.1 - 0.00052 20.2 1.2 0.001 19.3 0.0 2.0 3 0 0 3 3 3 1 Retrotransposon gag protein DUF2781 PF10914.8 GBG80420.1 - 0.095 13.1 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF3701 PF12482.8 GBG80420.1 - 3.1 7.9 5.7 51 4.0 3.3 2.5 2 0 0 2 2 2 0 Phage integrase protein RT_RNaseH PF17917.1 GBG80421.1 - 3.2e-36 123.8 0.2 5.9e-18 65.1 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80421.1 - 9.2e-34 115.5 0.0 6.2e-22 77.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80421.1 - 6.7e-19 68.3 0.1 1.5e-15 57.3 0.0 3.2 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG80421.1 - 0.12 12.7 0.0 0.6 10.4 0.0 2.4 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG80422.1 - 3.4e-11 43.1 0.1 5.1e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG80422.1 - 0.0018 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG80424.1 - 4.5e-15 55.9 0.9 4.3e-14 52.7 0.2 2.9 3 0 0 3 3 3 1 Integrase core domain DUF659 PF04937.15 GBG80424.1 - 5.2e-05 23.1 0.0 0.00015 21.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) FAM199X PF15814.5 GBG80424.1 - 1.3 8.0 5.6 2.5 7.1 5.6 1.3 1 0 0 1 1 1 0 Protein family FAM199X RVT_1 PF00078.27 GBG80425.1 - 3.1e-26 92.3 0.0 5.7e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80425.1 - 3.6e-26 91.1 0.0 8.5e-26 89.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80425.1 - 4e-24 84.9 0.0 9.7e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80425.1 - 1.9e-14 53.5 0.2 4.2e-14 52.4 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain APG17 PF04108.12 GBG80425.1 - 0.11 11.6 0.0 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG80426.1 - 3.2e-24 84.9 0.0 7.9e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80426.1 - 7e-23 80.9 0.0 1.6e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80426.1 - 4.8e-19 68.2 0.1 1.1e-18 67.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG80426.1 - 6e-05 23.2 0.0 0.00024 21.3 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein SlyX PF04102.12 GBG80426.1 - 0.0085 16.7 0.3 0.0085 16.7 0.3 4.3 5 0 0 5 5 5 1 SlyX Integrin_b_cyt PF08725.11 GBG80426.1 - 0.095 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain DUF2389 PF09493.10 GBG80426.1 - 0.13 12.9 1.1 0.56 10.9 0.1 2.4 2 0 0 2 2 2 0 Tryptophan-rich protein (DUF2389) RT_RNaseH PF17917.1 GBG80427.1 - 2.1e-14 53.7 0.0 5.1e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80427.1 - 7.9e-13 48.3 0.1 2.5e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DsrH PF04077.12 GBG80427.1 - 0.0016 18.5 6.6 81 3.4 0.1 7.3 6 2 2 8 8 8 0 DsrH like protein RVT_1 PF00078.27 GBG80428.1 - 2.2e-32 112.4 0.1 3.1e-32 111.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80428.1 - 1.3e-19 70.4 0.5 2.2e-19 69.7 0.5 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80428.1 - 6.1e-12 45.5 0.1 1.2e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG80429.1 - 1.4e-19 70.1 0.4 1.7e-05 25.4 0.0 4.9 3 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG80429.1 - 1.8e-16 60.2 0.1 7e-05 23.1 0.0 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 GBG80429.1 - 3.7e-05 22.2 0.0 0.034 12.5 0.0 3.1 3 0 0 3 3 3 3 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 GBG80429.1 - 0.041 13.5 0.1 2.9 7.4 0.0 2.2 1 1 0 2 2 2 0 PQQ-like domain PQQ PF01011.21 GBG80429.1 - 0.14 12.1 0.2 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat Nup160 PF11715.8 GBG80429.1 - 0.17 10.5 2.5 14 4.2 0.2 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Presenilin PF01080.17 GBG80430.1 - 0.69 8.6 8.4 0.79 8.4 8.4 1.3 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 GBG80430.1 - 7.7 5.4 8.6 8.8 5.2 8.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 zf-CCHC PF00098.23 GBG80431.1 - 1.1e-05 25.2 3.4 2.1e-05 24.4 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle RNase_H2-Ydr279 PF09468.10 GBG80431.1 - 0.081 13.1 0.4 0.081 13.1 0.4 3.0 2 1 1 3 3 3 0 Ydr279p protein family (RNase H2 complex component) wHTH domain zf-CCHC_4 PF14392.6 GBG80431.1 - 0.17 11.6 0.8 0.65 9.8 0.4 2.1 2 0 0 2 2 2 0 Zinc knuckle LpxI_N PF17930.1 GBG80431.1 - 0.36 10.7 3.1 0.47 10.4 1.5 2.0 2 0 0 2 2 2 0 LpxI N-terminal domain zf-CCHC_2 PF13696.6 GBG80431.1 - 1.3 8.9 5.6 2.3 8.1 5.6 1.5 1 0 0 1 1 1 0 Zinc knuckle CDC14 PF08045.11 GBG80431.1 - 5.5 6.0 10.4 0.16 11.0 0.3 2.7 3 0 0 3 3 3 0 Cell division control protein 14, SIN component Actin PF00022.19 GBG80432.1 - 1.7e-91 306.9 0.1 7.7e-91 304.7 0.1 1.7 1 1 0 1 1 1 1 Actin RVT_1 PF00078.27 GBG80434.1 - 6.6e-31 107.6 0.1 1.6e-30 106.3 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80434.1 - 7.4e-25 87.3 0.0 2.1e-24 85.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80434.1 - 5.2e-24 84.2 0.0 2.6e-23 81.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80434.1 - 3e-19 68.9 0.2 7.3e-19 67.6 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG80434.1 - 1.2e-07 31.6 0.0 2.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80434.1 - 7.2e-06 26.6 0.0 2.9e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80434.1 - 0.00011 22.7 0.0 0.00053 20.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG80434.1 - 0.00026 20.8 0.0 0.00069 19.5 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Retrotrans_gag PF03732.17 GBG80434.1 - 0.013 15.8 0.2 0.066 13.5 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein AMP-binding_C_2 PF14535.6 GBG80434.1 - 0.028 14.7 0.0 0.34 11.3 0.0 2.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Asp_protease PF09668.10 GBG80434.1 - 0.035 13.9 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG80435.1 - 1.2e-25 89.5 0.0 3e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80435.1 - 4e-15 56.0 0.0 1.3e-14 54.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80435.1 - 5e-10 39.6 0.0 1.4e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG80435.1 - 0.0018 18.9 0.0 0.0084 16.7 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80435.1 - 0.0019 18.7 0.0 0.0065 17.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG80435.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG80435.1 - 0.0055 17.0 0.1 0.053 13.8 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Josephin PF02099.17 GBG80436.1 - 0.0004 20.5 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Josephin HEAT PF02985.22 GBG80436.1 - 0.12 12.6 2.3 7.3 7.1 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Nop53 PF07767.11 GBG80436.1 - 0.24 10.7 9.3 0.51 9.7 9.3 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GBG80436.1 - 4.7 5.4 5.6 9.9 4.3 5.6 1.4 1 0 0 1 1 1 0 CDC45-like protein HEAT PF02985.22 GBG80437.1 - 0.19 12.1 3.9 5.5 7.5 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat Nop53 PF07767.11 GBG80437.1 - 0.2 11.0 9.3 0.38 10.1 9.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GBG80437.1 - 2.3 6.3 8.9 3.5 5.7 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG80437.1 - 5 5.3 5.7 7.8 4.7 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Tim44 PF04280.15 GBG80438.1 - 1.4e-36 125.8 0.3 1.4e-36 125.8 0.3 2.2 3 0 0 3 3 3 1 Tim44-like domain Apolipoprotein PF01442.18 GBG80438.1 - 0.0013 18.7 8.7 0.0013 18.7 8.7 3.0 3 1 0 3 3 3 1 Apolipoprotein A1/A4/E domain Gly_rich PF12810.7 GBG80438.1 - 0.0026 17.7 0.7 0.0035 17.3 0.7 1.2 1 0 0 1 1 1 1 Glycine rich protein FCD PF07729.12 GBG80438.1 - 0.012 16.1 0.0 0.12 12.8 0.0 2.4 2 0 0 2 2 2 0 FCD domain YtxH PF12732.7 GBG80438.1 - 0.072 13.6 18.2 0.41 11.2 2.5 4.1 3 1 1 4 4 4 0 YtxH-like protein Syntaxin_2 PF14523.6 GBG80438.1 - 0.14 12.5 5.5 0.46 10.9 5.5 1.9 1 0 0 1 1 1 0 Syntaxin-like protein DUF1451 PF07295.11 GBG80438.1 - 0.32 11.0 4.6 5.6 7.0 3.1 2.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain Leu_zip PF15294.6 GBG80438.1 - 3.8 6.9 9.1 1.1 8.7 4.8 2.1 2 0 0 2 2 2 0 Leucine zipper DUF948 PF06103.11 GBG80438.1 - 8.8 6.7 9.3 1.6e+02 2.6 5.8 3.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.11 GBG80438.1 - 9.1 6.4 16.0 2.6 8.1 8.8 3.3 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Com_YlbF PF06133.11 GBG80438.1 - 9.8 6.8 10.8 19 6.0 6.8 3.3 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA TPT PF03151.16 GBG80439.1 - 6e-17 61.9 16.9 6.7e-17 61.8 16.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GBG80439.1 - 1.4e-05 24.5 19.4 1.7e-05 24.2 19.4 1.2 1 0 0 1 1 1 1 UAA transporter family TMEM174 PF15029.6 GBG80439.1 - 0.0007 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Transmembrane protein 174 EamA PF00892.20 GBG80439.1 - 0.0075 16.4 26.1 0.054 13.7 9.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TMEM151 PF14857.6 GBG80439.1 - 6.9 5.5 6.4 1.5 7.7 0.6 2.0 2 0 0 2 2 2 0 TMEM151 family ABC1 PF03109.16 GBG80440.1 - 6.2e-31 107.0 0.0 1.6e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GBG80440.1 - 0.001 19.1 0.6 0.93 9.4 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family FCH PF00611.23 GBG80440.1 - 0.0096 16.2 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Myb_DNA-bind_4 PF13837.6 GBG80441.1 - 2.7e-09 37.3 3.1 3.7e-09 36.8 3.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG80441.1 - 1.3e-05 25.3 1.2 2e-05 24.8 1.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG80441.1 - 6.3e-05 23.0 0.6 8.5e-05 22.6 0.6 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG80441.1 - 0.00037 20.6 0.5 0.00076 19.6 0.5 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG80441.1 - 0.0011 19.3 1.1 0.0016 18.7 1.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like bHLH-MYC_N PF14215.6 GBG80444.1 - 2e-05 24.9 0.0 3.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal BUD22 PF09073.10 GBG80444.1 - 0.059 12.7 10.2 0.06 12.7 10.2 1.1 1 0 0 1 1 1 0 BUD22 MSP1_C PF07462.11 GBG80444.1 - 0.39 9.4 0.8 0.51 9.0 0.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SDA1 PF05285.12 GBG80444.1 - 0.57 9.5 17.7 0.65 9.4 17.7 1.0 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 GBG80444.1 - 0.78 9.7 13.9 0.85 9.5 13.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mpp10 PF04006.12 GBG80444.1 - 0.93 7.9 10.4 1.1 7.6 10.4 1.1 1 0 0 1 1 1 0 Mpp10 protein TTSSLRR PF12468.8 GBG80445.1 - 0.34 11.2 2.2 0.48 10.7 0.3 2.2 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein zf-CCHC PF00098.23 GBG80446.1 - 5.3e-05 23.1 3.7 9.7e-05 22.3 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG80446.1 - 0.032 14.1 1.7 0.062 13.1 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG80446.1 - 0.19 11.7 0.2 0.19 11.7 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF2924 PF11149.8 GBG80446.1 - 8.8 6.7 7.7 13 6.2 6.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2924) DUF4793 PF16041.5 GBG80447.1 - 1.2e-16 60.8 0.0 1.9e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) zf-C3HC4_3 PF13920.6 GBG80447.1 - 9.5e-15 54.2 7.0 1.7e-14 53.4 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG80447.1 - 3.3e-07 30.1 7.4 9.1e-07 28.7 7.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG80447.1 - 9.3e-07 28.6 8.1 1.8e-06 27.7 8.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GBG80447.1 - 2.5e-05 24.0 9.0 5.9e-05 22.8 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG80447.1 - 4.4e-05 23.7 8.7 0.00011 22.5 8.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG80447.1 - 0.0079 16.1 7.6 0.016 15.2 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 GBG80447.1 - 0.74 9.7 7.1 1.9 8.4 7.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RT_RNaseH PF17917.1 GBG80448.1 - 1.2e-25 89.8 1.1 2.2e-25 88.9 1.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80448.1 - 5.7e-19 68.0 0.1 1.4e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80448.1 - 3e-17 62.5 0.0 5.9e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80448.1 - 1.8e-16 60.4 0.0 7.6e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG80448.1 - 0.084 12.7 0.1 0.33 10.8 0.1 2.1 1 0 0 1 1 1 0 Integrase core domain Tup_N PF08581.10 GBG80448.1 - 2.4 8.5 6.0 1.8 8.9 1.8 2.5 2 0 0 2 2 2 0 Tup N-terminal RT_RNaseH_2 PF17919.1 GBG80449.1 - 1.3e-24 86.1 0.1 2.1e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80449.1 - 9e-18 64.5 0.3 1.4e-17 63.8 0.3 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG80450.1 - 2e-16 60.2 0.0 2.8e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SDA1 PF05285.12 GBG80452.1 - 0.013 14.9 54.5 0.017 14.6 54.5 1.1 1 0 0 1 1 1 0 SDA1 V_ATPase_I PF01496.19 GBG80452.1 - 0.51 8.2 4.4 0.75 7.6 4.4 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 GBG80452.1 - 0.57 9.3 4.2 0.78 8.9 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GBG80452.1 - 3.5 6.3 4.1 4.5 5.9 4.1 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG80452.1 - 5.4 5.1 61.4 8.1 4.5 61.4 1.2 1 0 0 1 1 1 0 Nop14-like family QRPTase_C PF01729.19 GBG80453.1 - 7.7e-58 195.0 1.4 1e-57 194.6 1.4 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 GBG80453.1 - 1.2e-26 92.6 0.2 3.1e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain QRPTase_C PF01729.19 GBG80454.1 - 1.5e-57 194.1 1.4 2.1e-57 193.6 1.4 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 GBG80454.1 - 2.3e-26 91.6 0.2 5.3e-26 90.5 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2312 PF10073.9 GBG80455.1 - 0.0097 15.5 0.5 0.075 12.7 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2312) SIKE PF05769.11 GBG80455.1 - 0.06 13.3 0.8 0.06 13.3 0.8 1.9 2 0 0 2 2 2 0 SIKE family Macoilin PF09726.9 GBG80455.1 - 0.16 10.5 2.4 0.16 10.5 2.4 1.1 1 0 0 1 1 1 0 Macoilin family Actin PF00022.19 GBG80456.1 - 5.2e-137 456.8 0.0 1.8e-136 455.0 0.0 1.7 1 1 0 1 1 1 1 Actin CDC45 PF02724.14 GBG80458.1 - 0.0071 14.7 30.9 0.0085 14.4 30.9 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG80458.1 - 1.4 7.1 39.4 2 6.5 39.4 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG80458.1 - 9 5.5 38.5 13 4.9 38.5 1.2 1 0 0 1 1 1 0 BUD22 RVT_1 PF00078.27 GBG80459.1 - 7.4e-35 120.5 0.1 1.3e-34 119.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80459.1 - 3e-25 88.1 0.0 8.8e-25 86.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80459.1 - 1e-24 86.8 0.0 1.9e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80459.1 - 8e-07 29.1 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80460.1 - 5.2e-36 124.2 0.0 9.7e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80460.1 - 5.8e-29 100.1 0.1 6.1e-28 96.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80460.1 - 4.3e-27 94.5 0.8 2.6e-26 91.9 0.2 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80460.1 - 2.9e-19 68.9 0.4 7.4e-19 67.6 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80460.1 - 6.4e-17 61.8 0.0 1.8e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80460.1 - 0.0015 18.7 0.1 0.0054 16.9 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG80460.1 - 0.085 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TPR_19 PF14559.6 GBG80461.1 - 0.00044 20.7 0.1 0.00044 20.7 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG80461.1 - 0.0017 18.1 0.1 0.0044 16.8 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG80461.1 - 0.0048 16.9 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat CsgE PF10627.9 GBG80461.1 - 1 9.6 5.8 2.6 8.3 5.8 1.8 1 0 0 1 1 1 0 Curli assembly protein CsgE NPV_P10 PF05531.12 GBG80461.1 - 1.9 9.0 5.4 4.1 7.9 2.6 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RT_RNaseH_2 PF17919.1 GBG80462.1 - 1.1e-24 86.4 0.0 2.2e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80462.1 - 1.7e-24 86.1 0.0 3e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80462.1 - 2.3e-13 50.2 1.5 1e-07 31.7 0.1 2.9 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80462.1 - 2.9e-07 30.4 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80462.1 - 1.2e-05 25.9 0.0 2.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG80462.1 - 9.1e-05 22.6 0.1 0.00036 20.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG80462.1 - 0.00012 22.6 0.0 0.00022 21.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease APG17 PF04108.12 GBG80462.1 - 0.0087 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG80463.1 - 1.4e-26 92.4 0.0 4.5e-26 90.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80463.1 - 1.4e-24 86.3 0.0 3.5e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80463.1 - 5e-11 42.6 0.2 7.4e-06 25.6 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) HIP1_clath_bdg PF16515.5 GBG80464.1 - 0.026 15.1 14.1 0.16 12.6 1.2 2.9 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2781 PF10914.8 GBG80464.1 - 0.029 14.8 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) OmpH PF03938.14 GBG80464.1 - 0.11 12.8 17.0 0.12 12.7 0.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) LPP PF04728.13 GBG80464.1 - 0.56 10.6 11.6 51 4.4 0.0 3.7 3 0 0 3 3 3 0 Lipoprotein leucine-zipper NAPRTase_C PF17956.1 GBG80464.1 - 1.7 9.1 4.6 8.8 6.8 0.1 3.2 2 1 1 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain Spc24 PF08286.11 GBG80464.1 - 1.7 8.9 6.8 8.4 6.7 0.3 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 zf-CCHC PF00098.23 GBG80465.1 - 3.6e-08 33.1 3.1 6.1e-08 32.4 3.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG80465.1 - 0.018 14.9 2.1 0.029 14.2 2.1 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4407 PF14362.6 GBG80465.1 - 3.2 7.0 17.7 5.2 6.3 17.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Thioredoxin PF00085.20 GBG80466.1 - 7.2e-23 80.5 2.1 5.2e-22 77.8 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG80466.1 - 6.3e-06 26.6 0.6 0.0006 20.2 0.1 2.8 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GBG80466.1 - 6.9e-06 25.9 0.1 1.2e-05 25.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GBG80466.1 - 0.00041 20.6 0.3 0.0011 19.2 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 GBG80466.1 - 0.0018 17.7 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 GBG80466.1 - 0.033 14.4 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin RT_RNaseH_2 PF17919.1 GBG80467.1 - 3.7e-11 42.9 0.0 7.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80467.1 - 6.3e-07 29.1 0.0 8.4e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG80467.1 - 0.045 13.2 21.2 0.059 12.8 21.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG80467.1 - 0.097 12.0 22.0 0.13 11.6 22.0 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG80467.1 - 0.15 10.3 24.4 0.19 9.9 24.4 1.0 1 0 0 1 1 1 0 Nop14-like family Bud13 PF09736.9 GBG80467.1 - 1.3 9.4 15.9 1.9 8.8 15.9 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex TFIIF_alpha PF05793.12 GBG80467.1 - 1.3 7.5 21.3 1.7 7.2 21.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GBG80467.1 - 1.6 7.0 18.1 2.1 6.5 18.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG80467.1 - 2 8.2 15.0 3 7.6 15.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Na_trans_assoc PF06512.13 GBG80467.1 - 2.2 8.5 15.8 3.3 7.9 15.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SAPS PF04499.15 GBG80467.1 - 3.5 6.3 9.0 4.6 5.9 9.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 GBG80467.1 - 8.4 4.4 10.4 12 3.9 10.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein KH_1 PF00013.29 GBG80468.1 - 6.5e-47 157.2 5.5 2.3e-16 59.4 0.6 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GBG80468.1 - 6.2e-13 48.4 1.9 0.0011 18.7 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GBG80468.1 - 1.6e-10 40.7 0.1 0.015 15.2 0.0 3.5 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 GBG80468.1 - 0.054 13.5 0.1 0.55 10.3 0.0 2.3 3 0 0 3 3 3 0 KH-like RNA-binding domain Mltc_N PF11873.8 GBG80468.1 - 0.062 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain KH_5 PF13184.6 GBG80468.1 - 0.087 12.9 5.6 0.48 10.5 0.4 3.3 3 0 0 3 3 3 0 NusA-like KH domain KH_1 PF00013.29 GBG80469.1 - 4.4e-47 157.8 5.5 2e-16 59.5 0.6 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GBG80469.1 - 3.6e-13 49.1 1.6 0.00096 18.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GBG80469.1 - 1.1e-10 41.2 0.1 0.013 15.4 0.0 3.5 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 GBG80469.1 - 0.042 13.8 0.1 0.48 10.4 0.0 2.4 3 0 0 3 3 3 0 KH-like RNA-binding domain Mltc_N PF11873.8 GBG80469.1 - 0.057 13.1 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain KH_5 PF13184.6 GBG80469.1 - 0.077 13.1 5.8 0.43 10.7 0.4 3.3 3 0 0 3 3 3 0 NusA-like KH domain DNA_primase_S PF01896.19 GBG80470.1 - 7.7e-56 188.9 0.3 1.2e-55 188.3 0.3 1.3 1 0 0 1 1 1 1 DNA primase small subunit WD40 PF00400.32 GBG80471.1 - 1.6e-31 107.9 10.0 1.7e-07 31.8 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG80471.1 - 5.5e-09 36.2 0.0 0.0008 19.7 0.0 3.6 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GBG80471.1 - 4.6e-07 29.5 0.2 2.4e-06 27.1 0.6 1.9 2 0 0 2 2 2 1 WD40-like domain PQQ_2 PF13360.6 GBG80471.1 - 0.00026 20.7 0.0 0.0087 15.7 0.0 2.1 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 GBG80471.1 - 0.0029 17.5 0.0 2.6 8.1 0.0 3.0 3 0 0 3 3 3 2 PQQ enzyme repeat Cytochrom_D1 PF02239.16 GBG80471.1 - 0.027 13.0 0.1 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain VID27 PF08553.10 GBG80471.1 - 0.053 12.6 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain DUF1279 PF06916.13 GBG80473.1 - 8.2e-22 77.6 0.1 1.6e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Type2_restr_D3 PF16902.5 GBG80473.1 - 0.14 12.1 0.3 1.3 9.0 0.0 2.4 2 1 1 3 3 3 0 Type-2 restriction enzyme D3 domain DUF659 PF04937.15 GBG80474.1 - 5.6e-11 42.5 0.0 1.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80474.1 - 1.7e-08 34.1 0.1 7.6e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region VHP PF02209.19 GBG80474.1 - 0.19 11.8 0.1 0.39 10.8 0.1 1.5 1 0 0 1 1 1 0 Villin headpiece domain Retrotrans_gag PF03732.17 GBG80475.1 - 0.016 15.4 0.0 0.057 13.7 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_5 PF14787.6 GBG80475.1 - 0.11 12.2 1.8 0.22 11.2 1.8 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG80475.1 - 0.69 10.1 4.7 2.3 8.4 4.7 2.0 1 0 0 1 1 1 0 Zinc knuckle Apolipoprotein PF01442.18 GBG80476.1 - 6.9e-05 22.8 2.4 0.00065 19.6 0.4 4.0 2 2 1 3 3 2 2 Apolipoprotein A1/A4/E domain Lectin_N PF03954.14 GBG80476.1 - 0.0013 18.5 9.4 0.0013 18.5 9.4 2.2 2 0 0 2 2 1 1 Hepatic lectin, N-terminal domain Spc7 PF08317.11 GBG80476.1 - 0.0022 16.9 26.3 0.0022 16.9 26.3 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein IL2 PF00715.17 GBG80476.1 - 0.019 14.9 10.2 0.023 14.6 9.0 1.7 1 1 0 1 1 1 0 Interleukin 2 Atg14 PF10186.9 GBG80476.1 - 0.12 11.5 26.7 0.35 9.9 26.7 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 GBG80476.1 - 0.15 12.2 21.2 3.1 7.9 3.6 4.1 1 1 1 3 3 3 0 bZIP transcription factor V_ATPase_I PF01496.19 GBG80476.1 - 0.25 9.2 13.4 0.41 8.5 9.5 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ApoO PF09769.9 GBG80476.1 - 0.53 10.3 7.2 0.7 9.9 3.2 2.8 2 1 0 2 2 2 0 Apolipoprotein O Bacillus_HBL PF05791.11 GBG80476.1 - 0.65 9.8 13.4 0.52 10.1 9.9 2.4 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) KASH_CCD PF14662.6 GBG80476.1 - 0.72 9.7 32.0 4 7.2 12.4 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Leu_zip PF15294.6 GBG80476.1 - 0.8 9.2 25.8 3.4 7.1 10.0 2.6 1 1 1 2 2 2 0 Leucine zipper TMF_TATA_bd PF12325.8 GBG80476.1 - 0.85 9.9 28.1 1.2 9.4 11.4 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 GBG80476.1 - 1.1 9.7 13.4 2.5 8.6 2.3 4.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Gp58 PF07902.11 GBG80476.1 - 1.2 7.4 9.8 1.6 6.9 9.8 1.2 1 0 0 1 1 1 0 gp58-like protein HAP1_N PF04849.13 GBG80476.1 - 1.3 8.1 29.5 28 3.8 28.0 2.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 GBG80476.1 - 1.4 9.0 11.4 0.58 10.2 5.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 GBG80476.1 - 2.8 8.3 7.6 0.67 10.3 2.3 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 GBG80476.1 - 3.1 8.1 14.9 3.1 8.2 8.1 3.2 1 1 0 2 2 2 0 Uncharacterized conserved protein TFIID_NTD2 PF04494.15 GBG80476.1 - 4.5 7.5 11.0 0.85 9.8 3.7 2.7 3 0 0 3 3 2 0 WD40 associated region in TFIID subunit, NTD2 domain HALZ PF02183.18 GBG80476.1 - 4.5 7.6 17.1 3.1 8.1 1.5 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper GIT_CC PF16559.5 GBG80476.1 - 4.5 7.2 20.0 8.6 6.3 6.0 3.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor USP8_interact PF08941.10 GBG80476.1 - 7.1 6.4 9.3 10 5.9 7.8 2.2 1 1 1 2 2 2 0 USP8 interacting YabA PF06156.13 GBG80476.1 - 7.4 7.3 21.1 5 7.8 6.6 3.5 2 1 1 3 3 3 0 Initiation control protein YabA TSC22 PF01166.18 GBG80476.1 - 8.4 6.8 13.2 8.2 6.8 1.2 3.5 3 1 1 4 4 3 0 TSC-22/dip/bun family Prominin PF05478.11 GBG80476.1 - 8.7 4.2 12.7 8.7 4.2 11.0 1.8 2 0 0 2 2 2 0 Prominin Allexi_40kDa PF05549.11 GBG80476.1 - 9 5.7 9.8 23 4.4 9.6 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein TEX13 PF15186.6 GBG80476.1 - 9.4 5.9 22.4 0.057 13.1 9.7 2.6 1 1 1 2 2 1 0 Testis-expressed sequence 13 protein family DDE_Tnp_4 PF13359.6 GBG80477.1 - 1.5e-19 70.2 0.0 1.5e-19 70.2 0.0 3.3 3 2 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80477.1 - 2.1e-14 53.6 0.0 5.9e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Plant transposon protein RVT_1 PF00078.27 GBG80478.1 - 4.9e-16 58.9 0.2 1.3e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80478.1 - 6.7e-11 42.1 0.0 1.6e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG80478.1 - 1.2e-08 34.6 1.5 3e-08 33.4 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG80478.1 - 3.2e-05 24.4 0.0 6.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80478.1 - 0.00032 21.3 0.0 0.00081 20.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG80478.1 - 0.00034 20.4 2.0 0.00088 19.0 2.0 1.8 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 GBG80478.1 - 3 6.0 7.4 4.4 5.5 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG80479.1 - 6.1 4.9 24.7 7.8 4.6 24.7 1.2 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.23 GBG80481.1 - 0.0029 17.6 2.6 0.0052 16.8 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG80481.1 - 0.01 15.8 2.2 0.025 14.6 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle RR_TM4-6 PF06459.12 GBG80481.1 - 0.59 9.9 10.3 0.74 9.6 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 GBG80481.1 - 4.4 7.0 10.6 5.3 6.7 10.6 1.2 1 0 0 1 1 1 0 AAA domain CCDC53 PF10152.9 GBG80481.1 - 4.6 7.6 8.2 6.9 7.1 7.9 1.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 GBG80481.1 - 5.2 5.7 6.1 6.2 5.5 6.1 1.2 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 GBG80481.1 - 9.3 5.7 13.7 12 5.3 13.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DNA_pol_phi PF04931.13 GBG80482.1 - 0.47 8.5 7.3 0.55 8.3 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG80482.1 - 0.66 8.2 4.6 0.68 8.2 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.19 GBG80482.1 - 1.2 9.8 13.3 3.2 8.4 13.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Paf1 PF03985.13 GBG80482.1 - 2 7.3 13.4 3.3 6.6 13.4 1.3 1 0 0 1 1 1 0 Paf1 DUF4637 PF15470.6 GBG80482.1 - 3.1 7.5 10.9 0.86 9.3 7.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Radial_spoke PF04712.12 GBG80482.1 - 3.6 6.4 10.5 5.2 5.9 10.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein CENP-B_dimeris PF09026.10 GBG80482.1 - 4.2 7.8 10.8 8.6 6.8 10.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 GBG80482.1 - 5.6 6.6 8.5 0.82 9.3 4.6 1.6 2 0 0 2 2 2 0 FAM176 family Nucleo_P87 PF07267.11 GBG80482.1 - 7.2 5.3 7.1 11 4.7 7.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF442 PF04273.13 GBG80483.1 - 0.038 14.1 0.7 0.052 13.6 0.7 1.2 1 0 0 1 1 1 0 Putative phosphatase (DUF442) ABC_membrane PF00664.23 GBG80484.1 - 8.9e-44 150.2 3.1 1.6e-43 149.3 3.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GBG80484.1 - 6.4e-34 117.4 0.0 1.3e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GBG80484.1 - 0.00052 19.5 0.0 0.0027 17.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GBG80484.1 - 0.017 14.8 0.1 0.047 13.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG80484.1 - 0.036 14.3 0.5 0.45 10.8 0.5 2.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GBG80484.1 - 0.045 13.3 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GBG80484.1 - 0.052 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 GBG80484.1 - 0.065 13.6 0.9 0.25 11.7 0.2 2.3 2 1 0 2 2 2 0 AAA ATPase domain ABC_membrane_2 PF06472.15 GBG80484.1 - 0.086 12.2 4.2 0.033 13.6 0.4 2.1 3 0 0 3 3 3 0 ABC transporter transmembrane region 2 SbcCD_C PF13558.6 GBG80484.1 - 0.17 12.1 0.3 1.7 8.9 0.3 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 GBG80484.1 - 0.2 11.4 4.2 0.27 10.9 0.9 2.7 2 1 0 2 2 2 0 AAA domain TPR_14 PF13428.6 GBG80485.1 - 4.8e-24 83.0 30.8 0.0016 19.1 1.3 10.9 3 2 8 11 11 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 GBG80485.1 - 2.1e-20 71.1 14.6 0.0054 16.7 0.0 11.1 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 GBG80485.1 - 1e-18 67.6 5.8 5.3e-05 23.6 0.2 6.9 7 1 2 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG80485.1 - 5.2e-13 48.1 0.0 0.19 12.0 0.0 9.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG80485.1 - 1.8e-11 44.2 17.6 0.39 11.0 0.1 8.9 4 2 4 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 GBG80485.1 - 5.1e-11 41.9 0.0 0.97 9.4 0.0 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 GBG80485.1 - 8.8e-09 35.9 36.8 0.0025 18.4 0.0 8.4 6 2 2 10 10 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 GBG80485.1 - 1.2e-07 31.6 0.4 0.47 11.0 0.0 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 GBG80485.1 - 3.6e-06 27.3 11.5 22 6.0 0.0 9.6 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG80485.1 - 5.5e-06 26.4 17.3 0.18 12.0 0.1 6.2 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG80485.1 - 1.3e-05 24.8 0.1 3.5 7.4 0.0 5.2 4 2 2 6 6 6 2 TPR repeat TPR_15 PF13429.6 GBG80485.1 - 7.3e-05 22.1 0.8 7.3e-05 22.1 0.8 3.9 2 1 1 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GBG80485.1 - 0.001 19.0 2.0 11 6.0 0.0 5.7 6 2 0 7 7 7 0 Mad3/BUB1 homology region 1 FAT PF02259.23 GBG80485.1 - 0.0023 17.2 13.1 0.58 9.3 0.5 5.1 1 1 4 5 5 5 1 FAT domain HAT PF02184.16 GBG80485.1 - 0.0068 16.3 3.4 0.49 10.4 0.0 3.9 4 0 0 4 4 4 1 HAT (Half-A-TPR) repeat Suf PF05843.14 GBG80485.1 - 0.065 13.2 0.0 40 4.1 0.0 3.6 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) TPR_20 PF14561.6 GBG80485.1 - 4.7 7.6 5.6 14 6.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 GBG80486.1 - 1e-35 121.8 0.0 1.6e-34 117.9 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80486.1 - 1.6e-31 108.7 0.1 4.4e-31 107.3 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG80486.1 - 0.0011 18.9 1.3 0.0025 17.8 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG80486.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG80486.1 - 0.039 14.2 0.1 0.082 13.2 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG80486.1 - 1.2 9.4 3.7 2.3 8.5 3.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Choline_kin_N PF04428.14 GBG80487.1 - 0.097 12.4 0.4 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Choline kinase N terminus IBN_N PF03810.19 GBG80488.1 - 1.7e-08 34.3 0.3 5.7e-08 32.6 0.3 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Peptidase_C1 PF00112.23 GBG80489.1 - 1.9e-58 198.1 5.5 3.2e-34 118.9 0.1 3.3 2 1 1 3 3 3 3 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GBG80489.1 - 0.26 10.0 0.2 0.44 9.2 0.2 1.2 1 0 0 1 1 1 0 Peptidase C1-like family Nop14 PF04147.12 GBG80490.1 - 0.0059 14.9 27.8 0.0059 14.9 27.8 1.0 1 0 0 1 1 1 1 Nop14-like family SpoIIIAH PF12685.7 GBG80490.1 - 0.077 12.8 7.3 0.08 12.8 7.3 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein SDA1 PF05285.12 GBG80490.1 - 0.12 11.7 32.9 0.13 11.7 32.9 1.0 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 GBG80490.1 - 0.32 9.4 28.0 0.37 9.2 28.0 1.0 1 0 0 1 1 1 0 Mpp10 protein Zip PF02535.22 GBG80490.1 - 0.35 10.0 4.9 0.37 10.0 4.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.12 GBG80490.1 - 0.93 8.8 28.6 1.1 8.6 28.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 GBG80490.1 - 2.8 6.6 3.0 2.9 6.6 3.0 1.0 1 0 0 1 1 1 0 Presenilin Na_trans_assoc PF06512.13 GBG80490.1 - 4.3 7.6 18.5 5.3 7.3 18.5 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated RPN2_C PF18004.1 GBG80490.1 - 4.8 7.1 10.0 6.5 6.6 10.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RhlB PF12300.8 GBG80490.1 - 8.2 6.5 9.6 12 6.0 9.6 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Cnd2 PF05786.14 GBG80490.1 - 8.7 4.9 23.1 12 4.4 23.1 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 RNA_polI_A34 PF08208.11 GBG80490.1 - 9.6 6.2 11.1 12 5.9 11.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 M16C_assoc PF08367.11 GBG80491.1 - 5.3e-27 94.5 0.0 5.3e-27 94.5 0.0 2.8 3 0 0 3 3 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 GBG80491.1 - 6.4e-08 32.8 5.1 1.5e-07 31.6 0.1 3.4 3 1 0 3 3 3 1 Peptidase M16 inactive domain BUD22 PF09073.10 GBG80491.1 - 0.00017 21.1 22.7 0.00028 20.4 22.7 1.2 1 0 0 1 1 1 1 BUD22 Mpp10 PF04006.12 GBG80491.1 - 0.00063 18.3 28.4 0.001 17.6 28.4 1.2 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 GBG80491.1 - 0.0007 19.1 28.6 0.0012 18.4 28.6 1.2 1 0 0 1 1 1 1 SDA1 DUF4604 PF15377.6 GBG80491.1 - 0.0024 18.3 39.1 0.0052 17.2 39.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Nop14 PF04147.12 GBG80491.1 - 0.056 11.7 32.0 0.015 13.6 28.9 1.5 2 0 0 2 2 2 0 Nop14-like family Drc1-Sld2 PF11719.8 GBG80491.1 - 0.23 11.0 25.9 0.012 15.2 20.4 1.6 2 0 0 2 2 2 0 DNA replication and checkpoint protein BSP_II PF05432.11 GBG80491.1 - 0.39 10.4 29.4 0.67 9.6 29.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) EMC3_TMCO1 PF01956.16 GBG80491.1 - 0.48 10.1 5.1 19 5.0 3.5 2.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Presenilin PF01080.17 GBG80491.1 - 0.81 8.4 16.7 1.2 7.8 16.7 1.2 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 GBG80491.1 - 1.1 9.0 23.9 0.44 10.3 14.0 2.4 2 0 0 2 2 2 0 Coilin N-terminus XRN_M PF17846.1 GBG80491.1 - 1.5 7.7 13.5 2.5 7.0 13.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain CDC45 PF02724.14 GBG80491.1 - 2 6.6 29.1 3.4 5.9 29.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GBG80491.1 - 3.4 6.3 9.2 6.2 5.5 9.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Eapp_C PF10238.9 GBG80491.1 - 6.9 6.7 16.8 2.1 8.4 4.1 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Pox_Ag35 PF03286.14 GBG80491.1 - 7.7 6.2 30.1 0.86 9.4 8.4 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein BSMAP PF12280.8 GBG80491.1 - 7.9 6.6 7.2 26 5.0 0.3 2.3 2 0 0 2 2 2 0 Brain specific membrane anchored protein SLC12 PF03522.15 GBG80491.1 - 9.4 5.1 16.2 16 4.3 16.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_M16 PF00675.20 GBG80492.1 - 2.7e-09 37.2 0.0 4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) CTK3 PF12243.8 GBG80492.1 - 0.097 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 RVT_1 PF00078.27 GBG80493.1 - 0.0084 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF563 PF04577.14 GBG80494.1 - 1.1e-11 45.2 0.0 2.4e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF563) PikAIV_N PF18605.1 GBG80494.1 - 0.17 11.5 1.6 0.3 10.7 1.6 1.4 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Presenilin PF01080.17 GBG80494.1 - 4.7 5.9 5.2 4.6 5.9 3.1 1.9 2 0 0 2 2 2 0 Presenilin Ald_Xan_dh_C2 PF02738.18 GBG80495.1 - 2.1e-137 458.9 0.0 2.7e-137 458.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase DUF2401 PF10287.9 GBG80495.1 - 0.043 13.4 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) FAD_binding_5 PF00941.21 GBG80496.1 - 9.5e-44 149.1 0.0 1.9e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 GBG80496.1 - 2.6e-32 110.6 0.0 5.9e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 GBG80496.1 - 3.3e-28 97.9 0.0 7.2e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 GBG80496.1 - 1.3e-27 96.3 0.1 2.4e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain RVT_1 PF00078.27 GBG80496.1 - 1.1e-24 87.2 0.0 2.6e-24 86.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ald_Xan_dh_C2 PF02738.18 GBG80496.1 - 1.1e-09 37.3 0.0 1.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2 PF00111.27 GBG80496.1 - 8.2e-09 35.3 1.2 1.5e-08 34.5 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 GBG80496.1 - 0.26 11.1 4.7 0.15 11.9 1.9 2.1 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B DUF563 PF04577.14 GBG80497.1 - 7.2e-16 59.0 0.0 2e-11 44.5 0.0 2.9 2 1 0 3 3 3 2 Protein of unknown function (DUF563) RF-1 PF00472.20 GBG80497.1 - 0.15 12.0 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 RF-1 domain PikAIV_N PF18605.1 GBG80497.1 - 0.76 9.4 4.6 0.44 10.2 1.3 2.3 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DivIC PF04977.15 GBG80498.1 - 0.016 15.0 9.6 0.4 10.5 6.3 2.6 2 0 0 2 2 2 0 Septum formation initiator Golgin_A5 PF09787.9 GBG80498.1 - 0.029 13.8 7.3 0.049 13.1 7.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 GBG80498.1 - 0.041 13.0 4.3 0.069 12.2 3.6 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prp19 PF08606.11 GBG80498.1 - 0.043 13.8 0.2 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Prp19/Pso4-like DUF948 PF06103.11 GBG80498.1 - 0.075 13.3 2.2 1.8 8.8 0.5 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Remorin_C PF03763.13 GBG80498.1 - 0.11 12.4 12.1 1.6 8.6 10.1 2.2 1 1 1 2 2 2 0 Remorin, C-terminal region FAM76 PF16046.5 GBG80498.1 - 0.13 11.6 1.5 0.18 11.1 1.5 1.3 1 0 0 1 1 1 0 FAM76 protein DUF4806 PF16064.5 GBG80498.1 - 0.15 12.4 0.6 0.29 11.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) Fez1 PF06818.15 GBG80498.1 - 0.23 11.9 12.3 0.37 11.2 10.9 1.9 1 1 2 3 3 3 0 Fez1 Mod_r PF07200.13 GBG80498.1 - 0.41 10.7 7.7 0.74 9.9 7.8 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein START PF01852.19 GBG80498.1 - 0.49 9.8 2.1 0.82 9.0 2.1 1.2 1 0 0 1 1 1 0 START domain PV-1 PF06637.11 GBG80498.1 - 9.4 4.9 11.8 3.1 6.5 8.4 1.7 2 0 0 2 2 2 0 PV-1 protein (PLVAP) DivIC PF04977.15 GBG80499.1 - 0.0049 16.6 8.7 0.52 10.1 7.3 2.4 2 1 0 2 2 2 1 Septum formation initiator Prp19 PF08606.11 GBG80499.1 - 0.033 14.2 0.4 0.13 12.3 0.0 2.1 2 1 0 2 2 2 0 Prp19/Pso4-like Remorin_C PF03763.13 GBG80499.1 - 0.038 13.9 14.0 1.1 9.2 12.7 2.1 1 1 1 2 2 2 0 Remorin, C-terminal region Atg14 PF10186.9 GBG80499.1 - 0.045 12.8 5.3 0.095 11.8 5.3 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 GBG80499.1 - 0.077 12.3 1.3 0.092 12.1 1.3 1.2 1 0 0 1 1 1 0 FAM76 protein HemX PF04375.14 GBG80499.1 - 0.11 11.8 10.0 0.16 11.2 0.0 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fez1 PF06818.15 GBG80499.1 - 0.25 11.8 13.5 0.23 11.9 10.9 1.8 1 1 1 2 2 2 0 Fez1 Golgin_A5 PF09787.9 GBG80499.1 - 0.36 10.2 12.1 0.21 11.0 10.4 1.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF4806 PF16064.5 GBG80499.1 - 0.41 11.0 1.6 0.76 10.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) Cwf_Cwc_15 PF04889.12 GBG80499.1 - 0.42 10.3 8.3 0.47 10.1 8.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GrpE PF01025.19 GBG80499.1 - 1.4 8.5 9.7 0.68 9.6 7.4 1.6 2 0 0 2 2 2 0 GrpE YscO-like PF16789.5 GBG80499.1 - 2.5 8.1 16.8 6.3 6.8 3.0 2.1 1 1 1 2 2 2 0 YscO-like protein PV-1 PF06637.11 GBG80499.1 - 4.3 6.0 10.0 5.5 5.7 10.0 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Integrase_H2C2 PF17921.1 GBG80500.1 - 4e-18 65.3 0.3 1.2e-17 63.8 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80500.1 - 3e-14 53.2 0.0 8.4e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG80500.1 - 6.6e-14 51.8 0.0 1.7e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80500.1 - 4.5e-12 46.0 0.2 8.4e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG80500.1 - 0.0044 17.2 1.9 0.0052 17.0 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG80500.1 - 0.0075 16.5 0.0 0.027 14.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80501.1 - 1.2e-31 108.7 0.0 2.7e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80501.1 - 1.4e-19 70.3 0.2 3.3e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80501.1 - 6.3e-08 32.4 0.1 9.2e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG80502.1 - 2.7e-23 82.5 0.0 4.4e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80502.1 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region rve PF00665.26 GBG80503.1 - 1.6e-12 47.6 0.0 4.6e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG80503.1 - 1.2e-11 44.3 0.0 2.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG80503.1 - 5.7e-10 39.2 2.2 8.3e-10 38.6 0.1 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG80503.1 - 0.00028 21.1 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Ribosomal_L37 PF08561.10 GBG80504.1 - 0.13 12.8 2.2 0.31 11.6 2.2 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 SAPS PF04499.15 GBG80505.1 - 0.46 9.2 12.8 0.56 8.9 12.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.10 GBG80505.1 - 1.2 9.4 22.2 1.9 8.8 0.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 GBG80505.1 - 1.8 7.2 16.6 2.4 6.8 16.6 1.1 1 0 0 1 1 1 0 Presenilin RT_RNaseH PF17917.1 GBG80506.1 - 3e-21 75.7 0.0 6.1e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80506.1 - 1.7e-16 60.5 0.0 3.1e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80506.1 - 3.7e-13 49.4 0.0 7.8e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG80506.1 - 0.00011 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG80506.1 - 0.00012 22.6 0.0 0.00028 21.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80506.1 - 0.00074 20.1 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80506.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG80507.1 - 1.7e-25 89.3 0.0 3.3e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80507.1 - 2.8e-24 85.0 0.0 5.7e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80507.1 - 3.1e-09 36.7 0.5 8.7e-07 28.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80507.1 - 0.021 14.6 0.0 0.066 13.0 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease DDE_Tnp_4 PF13359.6 GBG80508.1 - 2.2e-25 89.1 0.0 5.4e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease RT_RNaseH PF17917.1 GBG80508.1 - 1.1e-23 83.6 0.0 2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80508.1 - 1.1e-23 83.1 0.0 2.2e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80508.1 - 2.3e-13 50.2 0.0 3.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plant_tran PF04827.14 GBG80508.1 - 1.2e-10 41.4 0.0 2.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG80508.1 - 0.006 16.3 0.3 0.068 12.8 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain RVP_2 PF08284.11 GBG80508.1 - 0.007 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DDE_Tnp_1_2 PF13586.6 GBG80508.1 - 0.033 14.6 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG80509.1 - 0.048 14.0 0.6 0.37 11.2 0.1 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG80510.1 - 6e-20 71.7 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80510.1 - 5.9e-06 26.1 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80510.1 - 9.1e-05 23.0 0.0 0.00024 21.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80510.1 - 9.7e-05 22.2 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80510.1 - 0.00041 20.8 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease EFP_N PF08207.12 GBG80512.1 - 0.0039 17.2 0.3 1.1 9.4 0.1 2.7 2 0 0 2 2 2 2 Elongation factor P (EF-P) KOW-like domain APC_N_CC PF16689.5 GBG80512.1 - 0.024 14.7 1.2 0.5 10.5 0.1 2.9 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain FlaC_arch PF05377.11 GBG80512.1 - 0.088 13.2 0.3 0.32 11.4 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 GBG80512.1 - 0.15 12.7 0.0 0.15 12.7 0.0 2.7 2 2 1 3 3 3 0 Initiation control protein YabA RVT_1 PF00078.27 GBG80513.1 - 1e-17 64.4 0.0 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80513.1 - 4.3e-10 39.5 0.0 8.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MPS2 PF17060.5 GBG80513.1 - 0.053 12.8 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 SVIP PF15811.5 GBG80514.1 - 0.004 17.6 4.4 0.012 16.0 4.4 1.8 1 0 0 1 1 1 1 Small VCP/p97-interacting protein Lin-8 PF03353.15 GBG80514.1 - 0.075 12.6 7.4 0.12 11.9 7.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG80514.1 - 0.16 10.1 10.6 0.21 9.8 10.6 1.2 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 GBG80514.1 - 2.6 7.0 5.6 4.2 6.4 5.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SDA1 PF05285.12 GBG80514.1 - 3.1 7.1 13.5 4.5 6.6 13.5 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG80514.1 - 3.1 6.0 12.0 4.1 5.6 12.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 GBG80517.1 - 1.9 7.8 16.4 2.4 7.5 16.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RVT_1 PF00078.27 GBG80518.1 - 7.1e-12 45.3 0.1 1.7e-11 44.1 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rota_Capsid_VP6 PF00980.17 GBG80518.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 Retrotrans_gag PF03732.17 GBG80520.1 - 0.0009 19.5 0.5 0.052 13.8 0.0 3.3 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG80520.1 - 0.0091 15.9 0.2 0.023 14.6 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG80521.1 - 4.3e-31 106.9 0.0 2.1e-16 59.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80521.1 - 4.4e-29 100.9 0.0 8.8e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80521.1 - 5.7e-26 91.4 0.0 1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80521.1 - 7.3e-15 54.8 1.7 1.7e-14 53.7 1.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80521.1 - 1.8e-05 24.9 0.0 4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80521.1 - 0.029 14.6 0.3 0.077 13.2 0.3 1.8 1 0 0 1 1 1 0 H2C2 zinc finger IFP_35_N PF07334.13 GBG80522.1 - 1.3 9.2 9.8 3.6 7.7 9.3 2.1 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus RVT_1 PF00078.27 GBG80525.1 - 9.3e-29 100.5 0.0 1.4e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80525.1 - 2.3e-07 30.6 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Atg14 PF10186.9 GBG80525.1 - 4.1e-07 29.4 0.0 0.00039 19.6 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 Asp_protease_2 PF13650.6 GBG80525.1 - 5.1e-07 30.3 0.0 1.5e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80525.1 - 0.00025 21.6 0.0 0.00061 20.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80525.1 - 0.079 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease BK_channel_a PF03493.18 GBG80526.1 - 7.3e-22 77.4 0.0 1.7e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 GBG80526.1 - 1.2e-14 54.0 0.7 2.5e-14 53.0 0.7 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 GBG80526.1 - 3e-08 33.2 7.1 5.2e-08 32.4 7.1 1.2 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 GBG80526.1 - 0.069 13.0 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4233 PF14017.6 GBG80526.1 - 0.18 12.1 2.7 0.66 10.3 2.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) IRK PF01007.20 GBG80526.1 - 0.19 11.6 0.4 0.61 9.9 0.4 1.8 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Myb_DNA-bind_4 PF13837.6 GBG80527.1 - 0.00021 21.6 1.0 0.00069 20.0 0.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain tRNA_int_end_N2 PF12928.7 GBG80527.1 - 0.17 12.0 0.6 4.8 7.4 0.0 3.0 3 0 0 3 3 3 0 tRNA-splicing endonuclease subunit sen54 N-term DDE_Tnp_4 PF13359.6 GBG80528.1 - 0.16 11.6 0.1 7.5 6.2 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease Auts2 PF15336.6 GBG80529.1 - 0.01 15.9 3.0 0.01 15.9 3.0 2.0 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein zf-CCHC PF00098.23 GBG80529.1 - 0.015 15.4 0.2 0.04 14.0 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG80530.1 - 0.013 15.7 0.3 0.04 14.2 0.1 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG80532.1 - 2.7e-32 110.8 0.0 5.6e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80532.1 - 4e-29 101.0 0.1 7.9e-29 100.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80532.1 - 6.3e-18 64.6 0.1 1.5e-17 63.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80532.1 - 1.8e-15 57.0 0.0 3.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80532.1 - 6.6e-10 39.2 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG80532.1 - 3.4e-05 24.3 0.0 7.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG80532.1 - 0.0003 20.9 0.0 0.00076 19.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG80532.1 - 0.0031 18.1 0.0 0.0068 17.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease End3 PF12761.7 GBG80533.1 - 3.3 7.9 22.9 0.27 11.4 15.5 2.4 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 ThiC_Rad_SAM PF01964.18 GBG80535.1 - 7.7e-195 647.5 0.0 8.9e-195 647.3 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family RT_RNaseH_2 PF17919.1 GBG80536.1 - 2.8e-29 101.1 0.0 9.8e-29 99.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80536.1 - 4.5e-29 100.8 0.5 1.5e-28 99.1 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80536.1 - 2.2e-26 92.8 0.1 4.5e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FNIP_M PF14637.6 GBG80536.1 - 0.024 14.6 0.2 3 7.8 0.0 2.4 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain RVT_1 PF00078.27 GBG80537.1 - 3.3e-15 56.2 0.0 5.3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80538.1 - 3.7e-29 100.7 0.0 7.9e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80538.1 - 4.5e-23 81.5 0.0 1.4e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Tic22 PF04278.12 GBG80538.1 - 0.059 12.7 0.1 1 8.7 0.5 2.3 2 0 0 2 2 2 0 Tic22-like family RVT_1 PF00078.27 GBG80539.1 - 2.3e-34 118.9 0.0 3.9e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80539.1 - 1.9e-30 104.8 0.0 5.8e-30 103.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80539.1 - 5.2e-30 103.8 0.1 1.4e-29 102.5 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3987 PF13148.6 GBG80539.1 - 6 5.8 21.1 0.073 12.1 8.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_7 PF12775.7 GBG80540.1 - 8e-54 181.9 0.0 4.5e-42 143.6 0.0 2.2 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_lid_1 PF17857.1 GBG80540.1 - 4.4e-09 36.5 0.1 1.3e-08 34.9 0.1 1.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 GBG80540.1 - 0.0028 17.9 0.0 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 GBG80540.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 GBG80540.1 - 0.016 15.2 0.0 0.9 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GBG80540.1 - 0.032 14.6 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 GBG80540.1 - 0.038 13.2 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 GBG80540.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GBG80540.1 - 0.14 11.6 0.1 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GBG80541.1 - 3.8e-54 183.0 0.0 2.6e-42 144.4 0.0 2.1 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 GBG80541.1 - 0.0019 18.5 0.0 0.0072 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GBG80541.1 - 0.0067 16.4 0.0 0.63 10.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) TniB PF05621.11 GBG80541.1 - 0.0071 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 GBG80541.1 - 0.022 15.2 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 GBG80541.1 - 0.026 13.7 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 GBG80541.1 - 0.069 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GBG80541.1 - 0.086 12.2 0.1 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 GBG80541.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.13 GBG80541.1 - 0.23 10.6 0.0 0.47 9.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.7 GBG80541.1 - 0.25 10.2 0.0 0.42 9.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF659 PF04937.15 GBG80543.1 - 3.6e-30 104.9 0.1 5.9e-30 104.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG80544.1 - 2.2e-18 66.1 0.0 4.3e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80544.1 - 4.4e-08 33.3 0.0 8.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PBP_N PF17093.5 GBG80544.1 - 7.6 6.8 7.1 20 5.4 7.1 1.7 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus RVT_1 PF00078.27 GBG80545.1 - 1e-22 80.8 0.1 1.7e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG80547.1 - 1.6e-30 106.3 0.0 2.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80547.1 - 2.4e-06 28.1 0.0 4.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG80547.1 - 4.3e-05 23.3 0.0 8.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG80547.1 - 5e-05 23.8 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80547.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG80548.1 - 3.7e-31 107.1 0.0 1.1e-30 105.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80548.1 - 1e-29 102.9 0.2 4.1e-29 100.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80548.1 - 5.7e-19 68.0 0.7 1.4e-18 66.7 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80548.1 - 0.0028 17.8 0.0 0.0078 16.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80548.1 - 0.0063 16.7 0.1 0.016 15.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG80548.1 - 0.054 13.8 0.4 0.87 9.9 0.0 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein Herpes_ORF11 PF04797.13 GBG80548.1 - 0.14 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus dUTPase protein DUF4569 PF15133.6 GBG80548.1 - 7.1 6.3 14.5 6.4 6.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) RVT_1 PF00078.27 GBG80550.1 - 3.1e-30 105.3 0.1 4.8e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80550.1 - 6.3e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG80550.1 - 3.4e-05 24.3 0.0 7.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80550.1 - 5.7e-05 23.7 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG80550.1 - 0.065 12.3 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Argos PF11581.8 GBG80550.1 - 0.065 13.3 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos Retrotrans_gag PF03732.17 GBG80551.1 - 0.001 19.3 0.0 0.001 19.3 0.0 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein ERM PF00769.19 GBG80551.1 - 0.088 12.6 10.2 0.2 11.5 10.2 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_9 PF12781.7 GBG80554.1 - 8.6e-70 234.3 1.5 5.3e-67 225.2 0.0 3.2 3 1 1 4 4 4 2 ATP-binding dynein motor region MT PF12777.7 GBG80554.1 - 9.7e-14 51.1 0.1 9.7e-14 51.1 0.1 1.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor DUF1640 PF07798.11 GBG80554.1 - 0.018 15.1 1.7 0.047 13.7 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) APG6_N PF17675.1 GBG80554.1 - 0.019 15.5 1.2 0.019 15.5 1.2 2.6 3 0 0 3 3 2 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 GBG80554.1 - 0.038 13.6 0.9 0.094 12.3 0.9 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4349 PF14257.6 GBG80554.1 - 0.046 13.2 0.7 0.084 12.3 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) EMP24_GP25L PF01105.24 GBG80554.1 - 0.15 11.9 0.4 0.37 10.7 0.4 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 GBG80554.1 - 0.19 9.9 3.6 0.34 9.0 3.6 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA UPF0242 PF06785.11 GBG80554.1 - 0.36 10.9 4.7 0.14 12.3 1.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1043 PF06295.12 GBG80554.1 - 0.4 10.7 3.9 0.98 9.4 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) RasGAP_C PF03836.15 GBG80554.1 - 0.43 10.7 4.0 0.55 10.4 1.1 2.2 2 0 0 2 2 2 0 RasGAP C-terminus DUF4201 PF13870.6 GBG80554.1 - 0.44 10.2 10.1 0.15 11.7 5.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 GBG80554.1 - 0.48 10.6 9.9 0.054 13.7 4.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PI3K_P85_iSH2 PF16454.5 GBG80554.1 - 0.51 9.9 8.1 1.5 8.4 3.6 2.7 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tropomyosin_1 PF12718.7 GBG80554.1 - 0.61 10.2 9.7 8.1 6.6 0.2 2.5 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 GBG80554.1 - 0.65 8.8 9.1 0.05 12.5 3.8 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein MscS_porin PF12795.7 GBG80554.1 - 0.65 9.5 14.2 0.38 10.3 5.7 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Retrotrans_gag PF03732.17 GBG80554.1 - 2.4 8.5 4.5 0.8 10.0 0.0 2.5 3 0 0 3 3 2 0 Retrotransposon gag protein DHR10 PF18595.1 GBG80554.1 - 2.7 8.1 17.3 0.38 10.8 7.4 2.8 3 0 0 3 3 2 0 Designed helical repeat protein 10 domain Snapin_Pallidin PF14712.6 GBG80554.1 - 5.6 7.5 8.8 1.4 9.4 4.4 2.5 2 0 0 2 2 1 0 Snapin/Pallidin DUF4795 PF16043.5 GBG80554.1 - 8.7 5.9 10.0 0.96 9.0 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) TMF_TATA_bd PF12325.8 GBG80554.1 - 8.8 6.6 13.3 0.11 12.7 3.8 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.11 GBG80554.1 - 9.2 6.9 6.2 9.8 6.8 1.4 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal AAA_9 PF12781.7 GBG80555.1 - 9e-47 159.0 0.3 6.9e-46 156.1 0.0 2.3 2 1 1 3 3 3 1 ATP-binding dynein motor region MT PF12777.7 GBG80555.1 - 4.7e-14 52.2 0.1 7.9e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor APG6_N PF17675.1 GBG80555.1 - 0.0071 16.9 1.2 0.015 15.9 1.2 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF1640 PF07798.11 GBG80555.1 - 0.02 14.9 1.7 0.039 14.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Spc7 PF08317.11 GBG80555.1 - 0.024 13.5 3.8 0.042 12.7 3.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 GBG80555.1 - 0.025 14.8 4.1 0.045 14.0 4.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 GBG80555.1 - 0.038 13.6 0.9 0.077 12.6 0.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4349 PF14257.6 GBG80555.1 - 0.041 13.3 0.7 0.069 12.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) TMF_TATA_bd PF12325.8 GBG80555.1 - 0.049 13.8 3.8 0.094 12.9 3.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 GBG80555.1 - 0.062 13.0 5.6 0.13 12.0 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF745 PF05335.13 GBG80555.1 - 0.091 12.5 5.5 0.19 11.5 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) EMP24_GP25L PF01105.24 GBG80555.1 - 0.15 12.0 0.4 0.31 11.0 0.4 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CCDC144C PF14915.6 GBG80555.1 - 0.16 11.0 6.9 0.27 10.3 6.9 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region EzrA PF06160.12 GBG80555.1 - 0.19 9.9 3.6 0.28 9.3 3.6 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Snapin_Pallidin PF14712.6 GBG80555.1 - 0.31 11.5 4.3 1.1 9.8 4.3 2.0 1 0 0 1 1 1 0 Snapin/Pallidin DUF4795 PF16043.5 GBG80555.1 - 0.38 10.3 4.4 0.79 9.3 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1043 PF06295.12 GBG80555.1 - 0.4 10.7 3.9 0.81 9.7 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DHR10 PF18595.1 GBG80555.1 - 0.64 10.1 10.2 0.44 10.6 7.9 1.9 2 0 0 2 2 1 0 Designed helical repeat protein 10 domain Retrotrans_gag PF03732.17 GBG80555.1 - 0.67 10.3 0.0 0.67 10.3 0.0 2.5 3 0 0 3 3 2 0 Retrotransposon gag protein Nup54 PF13874.6 GBG80555.1 - 0.96 9.5 6.0 1.9 8.6 6.0 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 FliJ PF02050.16 GBG80555.1 - 1.5 9.1 11.3 0.46 10.7 7.8 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein RT_RNaseH_2 PF17919.1 GBG80556.1 - 5e-24 84.2 0.0 1.1e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80556.1 - 3.9e-19 68.9 0.0 1.1e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80556.1 - 0.0022 18.2 0.3 0.075 13.3 0.0 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein DUF3006 PF11213.8 GBG80556.1 - 0.078 13.2 0.7 0.16 12.2 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) RT_RNaseH PF17917.1 GBG80557.1 - 7.6e-29 100.1 0.2 2.3e-28 98.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80557.1 - 1.3e-27 95.7 0.0 3.6e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80557.1 - 1.5e-12 47.6 0.1 3.5e-11 43.0 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80557.1 - 3.7e-10 39.8 0.0 9.2e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF3510 PF12022.8 GBG80557.1 - 0.24 11.8 2.8 1.3 9.4 2.8 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) RVT_1 PF00078.27 GBG80558.1 - 4.8e-27 94.9 0.5 2.4e-26 92.6 0.2 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80558.1 - 5.3e-07 29.6 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG80558.1 - 0.024 14.3 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RT_RNaseH PF17917.1 GBG80559.1 - 4e-13 49.6 0.0 3.3e-12 46.6 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80559.1 - 9.1e-12 44.9 0.0 5.6e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80559.1 - 3.3e-10 40.2 0.0 8.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG80559.1 - 2.9e-08 34.2 0.0 6.9e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG80559.1 - 3e-06 27.2 0.2 3e-06 27.2 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG80559.1 - 1.4e-05 25.6 0.0 3.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG80559.1 - 0.0052 17.0 0.4 0.0052 17.0 0.4 4.3 6 0 0 6 6 6 1 Retrotransposon gag protein RVP PF00077.20 GBG80559.1 - 0.01 16.2 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80559.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG80559.1 - 0.12 12.6 0.2 0.26 11.5 0.2 1.6 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG80560.1 - 2.8e-05 24.6 0.1 5.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80560.1 - 0.0045 17.6 0.1 0.0091 16.6 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80560.1 - 0.018 14.8 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG80560.1 - 0.03 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG80561.1 - 0.012 15.8 0.3 0.061 13.6 0.1 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein Kelch_3 PF13415.6 GBG80561.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Galactose oxidase, central domain Topo-VIb_trans PF09239.11 GBG80562.1 - 1.7e-54 184.0 0.0 3.7e-54 182.9 0.0 1.6 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.26 GBG80562.1 - 6.9e-06 26.5 0.0 7.2e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GBG80562.1 - 1e-05 25.4 0.2 6.7e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RVT_1 PF00078.27 GBG80563.1 - 2.3e-13 50.2 0.1 4e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_23 PF13489.6 GBG80563.1 - 6e-08 32.7 0.0 2.7e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG80563.1 - 6.7e-06 26.8 0.0 1.7e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG80563.1 - 8.9e-06 25.6 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG80563.1 - 9.3e-06 26.3 0.0 3.7e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG80563.1 - 0.00013 22.5 0.0 0.00045 20.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 GBG80563.1 - 0.00016 21.1 0.0 0.0003 20.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 GBG80563.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain HVSL PF09749.9 GBG80564.1 - 4.7e-50 170.3 0.0 1.6e-49 168.5 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised conserved protein PRIMA1 PF16101.5 GBG80564.1 - 0.89 9.6 7.2 1.9 8.5 7.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG80564.1 - 1.1 8.6 5.7 1.2 8.6 3.2 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PI3_PI4_kinase PF00454.27 GBG80565.1 - 1.8e-30 106.6 0.0 3.7e-20 72.8 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GBG80565.1 - 3.5e-20 72.2 0.0 6.3e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Evr1_Alr PF04777.13 GBG80567.1 - 1.9e-27 95.6 0.4 3e-27 95.0 0.4 1.3 1 0 0 1 1 1 1 Erv1 / Alr family MyTH4 PF00784.17 GBG80567.1 - 0.053 14.0 0.2 0.089 13.3 0.2 1.3 1 0 0 1 1 1 0 MyTH4 domain Kinesin PF00225.23 GBG80569.1 - 1.3e-12 47.3 0.1 1.3e-12 47.3 0.1 2.0 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GBG80569.1 - 1.6e-05 24.9 3.3 0.00015 21.8 0.0 2.8 2 1 0 2 2 2 1 Microtubule binding S1FA PF04689.13 GBG80569.1 - 1.3 9.2 3.3 2 8.6 0.8 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA DUF1319 PF07028.11 GBG80569.1 - 1.5 9.1 14.8 9.6 6.5 4.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Leucyl-specific PF14795.6 GBG80569.1 - 2 8.5 10.3 0.081 13.0 1.4 2.8 2 1 0 2 2 2 0 Leucine-tRNA synthetase-specific domain ATG16 PF08614.11 GBG80569.1 - 2.2 8.4 31.8 0.15 12.3 11.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 GBG80569.1 - 2.8 8.4 14.7 1.5 9.2 1.6 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 GBG80569.1 - 6.5 6.8 13.6 17 5.5 1.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF659 PF04937.15 GBG80571.1 - 7e-10 39.0 0.2 1.2e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG80571.1 - 0.0019 18.8 0.2 0.0044 17.5 0.2 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80571.1 - 0.016 15.8 0.1 0.049 14.3 0.1 1.8 1 0 0 1 1 1 0 Aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG80571.1 - 0.08 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RPW8 PF05659.11 GBG80573.1 - 0.053 13.2 2.8 0.16 11.7 2.8 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BBP1_C PF15272.6 GBG80573.1 - 0.22 11.3 13.1 0.017 14.9 3.3 2.5 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal KapB PF08810.10 GBG80573.1 - 0.63 10.2 5.6 0.21 11.8 2.1 2.1 2 0 0 2 2 2 0 Kinase associated protein B zf-ZPR1 PF03367.13 GBG80573.1 - 3.6 7.4 5.1 5.8 6.8 0.6 2.7 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DUF1640 PF07798.11 GBG80573.1 - 5.3 7.1 11.5 0.05 13.6 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) gag-asp_proteas PF13975.6 GBG80574.1 - 2.3e-07 31.3 0.0 4.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80574.1 - 3.8e-06 27.4 0.0 8.9e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG80574.1 - 0.00055 19.7 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease cNMP_binding PF00027.29 GBG80574.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain RVP_2 PF08284.11 GBG80574.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG80576.1 - 7.9e-06 26.4 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80576.1 - 3.1e-05 24.5 0.1 8.3e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG80576.1 - 0.0038 17.0 0.0 0.0069 16.2 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG80576.1 - 0.041 13.7 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease DEAD PF00270.29 GBG80577.1 - 2e-44 151.5 0.1 7.9e-44 149.5 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG80577.1 - 1.1e-28 99.8 0.0 5.1e-28 97.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG80577.1 - 8.6e-05 22.6 0.0 0.00039 20.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_L34e PF01199.18 GBG80578.1 - 1.9e-43 146.7 6.2 2.7e-43 146.2 6.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e PRODH PF18327.1 GBG80578.1 - 0.025 14.8 0.1 0.043 14.0 0.1 1.3 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain FhuF_C PF11575.8 GBG80578.1 - 0.032 14.1 2.3 2.3 8.2 0.1 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain gag-asp_proteas PF13975.6 GBG80580.1 - 1.4e-06 28.7 0.1 3e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80580.1 - 4e-05 24.2 0.1 8.5e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG80580.1 - 0.0075 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG80580.1 - 0.008 16.2 3.0 0.014 15.4 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 GBG80580.1 - 0.012 15.4 0.2 0.02 14.7 0.2 1.3 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG80580.1 - 0.079 12.6 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVT_1 PF00078.27 GBG80582.1 - 1.6e-30 106.3 0.1 2.5e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80582.1 - 1.1e-12 48.2 0.0 2.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG80582.1 - 2.2e-12 46.9 1.0 7.5e-12 45.2 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG80582.1 - 0.068 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG80584.1 - 0.041 14.0 2.6 0.074 13.2 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Neuraminidase PF18413.1 GBG80584.1 - 0.91 9.2 8.8 0.067 12.8 3.4 1.8 3 0 0 3 3 3 0 Neuraminidase-like domain DUF659 PF04937.15 GBG80585.1 - 2.9e-10 40.2 0.1 5.2e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG80586.1 - 4.2e-13 49.5 0.0 9.7e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF659 PF04937.15 GBG80586.1 - 2.3e-12 47.0 0.6 4.8e-12 46.0 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG80586.1 - 3.6e-06 26.9 0.0 7.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80586.1 - 0.00053 20.2 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80586.1 - 0.00074 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG80586.1 - 0.049 13.7 0.8 0.1 12.7 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG80588.1 - 6.2e-40 136.5 0.2 1e-39 135.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80588.1 - 3.3e-05 23.6 5.8 0.00011 21.9 2.4 2.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region STAG PF08514.11 GBG80592.1 - 3.5e-25 88.1 0.0 8.1e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 STAG domain HEAT PF02985.22 GBG80592.1 - 5.3e-05 23.1 0.2 0.92 9.9 0.1 4.3 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 GBG80592.1 - 0.00074 19.6 2.5 0.65 10.0 0.1 3.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GBG80592.1 - 0.024 15.0 0.2 2.3 8.7 0.1 3.1 2 0 0 2 2 2 0 HEAT repeats IFRD PF05004.13 GBG80592.1 - 1.1 8.3 13.8 0.15 11.2 0.1 3.7 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Myb_DNA-bind_4 PF13837.6 GBG80593.1 - 4.7e-09 36.5 1.0 7.7e-09 35.8 1.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Chromo PF00385.24 GBG80594.1 - 1.7e-11 43.8 0.0 3.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG80594.1 - 1.7e-09 37.9 0.2 5.6e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG80595.1 - 7.2e-27 94.3 0.1 1.2e-26 93.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRCF PF03461.15 GBG80595.1 - 0.036 14.5 0.1 8 6.9 0.0 2.7 3 0 0 3 3 3 0 TRCF domain RE_MjaI PF09568.10 GBG80595.1 - 0.21 11.4 0.0 24 4.7 0.0 2.2 2 0 0 2 2 2 0 MjaI restriction endonuclease Integrase_H2C2 PF17921.1 GBG80596.1 - 3.4e-12 46.3 0.2 1e-11 44.7 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80596.1 - 1.7e-06 28.2 0.0 4.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG80596.1 - 0.00084 19.6 0.5 0.0062 16.8 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF659 PF04937.15 GBG80597.1 - 0.001 18.9 0.0 0.0053 16.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Raftlin PF15250.6 GBG80597.1 - 0.7 8.6 14.3 10 4.8 15.8 2.1 2 0 0 2 2 2 0 Raftlin Clathrin PF00637.20 GBG80598.1 - 7.6e-195 638.6 31.4 2.8e-32 111.5 0.2 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 GBG80598.1 - 2e-31 107.7 0.9 1.8e-30 104.7 0.2 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 GBG80598.1 - 3.7e-26 90.1 0.0 4.7e-08 33.0 0.0 6.3 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin-link PF09268.10 GBG80598.1 - 1.6e-09 37.0 0.1 4.4e-09 35.5 0.1 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 GBG80598.1 - 0.0016 17.6 1.5 0.5 9.4 0.1 3.0 3 0 0 3 3 3 2 Coatomer WD associated region TPR_1 PF00515.28 GBG80598.1 - 0.0093 15.7 1.5 21 5.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG80598.1 - 0.034 14.3 0.4 4 7.8 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ASRT PF07100.11 GBG80598.1 - 0.039 14.0 0.1 0.15 12.2 0.1 2.0 1 0 0 1 1 1 0 Anabaena sensory rhodopsin transducer TPR_14 PF13428.6 GBG80598.1 - 0.051 14.4 1.8 50 5.1 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat DpnII PF04556.12 GBG80598.1 - 0.11 11.7 1.7 0.19 11.0 0.1 2.1 2 0 0 2 2 2 0 DpnII restriction endonuclease RVT_1 PF00078.27 GBG80599.1 - 5.3e-42 143.8 0.7 3.6e-33 115.0 0.1 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80599.1 - 6.9e-17 61.3 0.0 1.4e-15 57.2 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80599.1 - 1.8e-05 25.0 0.0 5.5e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Trans_reg_C PF00486.28 GBG80599.1 - 0.053 13.6 0.1 0.89 9.7 0.0 2.8 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal DUF2990 PF11693.8 GBG80599.1 - 0.12 12.5 0.0 6.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Integrase_H2C2 PF17921.1 GBG80600.1 - 6.5e-11 42.2 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80601.1 - 5.7e-29 101.2 0.1 7.8e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NESP55 PF06390.12 GBG80601.1 - 0.0042 16.7 11.0 0.0042 16.7 11.0 1.7 2 0 0 2 2 2 1 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 GBG80601.1 - 0.017 15.1 6.9 0.045 13.7 6.9 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-CCHC PF00098.23 GBG80602.1 - 0.04 14.0 1.9 0.073 13.2 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG80602.1 - 0.069 12.8 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like gag-asp_proteas PF13975.6 GBG80603.1 - 0.024 15.2 0.0 0.064 13.8 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80603.1 - 0.037 13.8 0.1 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG80604.1 - 0.0013 19.0 2.3 0.0054 17.0 0.9 3.6 4 1 0 4 4 4 2 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG80604.1 - 0.0051 16.8 2.6 0.018 15.0 2.6 1.9 1 0 0 1 1 1 1 Zinc knuckle IceA2 PF05862.11 GBG80604.1 - 0.17 11.8 0.9 0.48 10.4 0.2 2.0 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein CpXC PF14353.6 GBG80604.1 - 0.19 11.7 1.9 0.49 10.5 0.0 2.5 2 0 0 2 2 2 0 CpXC protein zf-CCHC PF00098.23 GBG80604.1 - 2.5 8.3 4.1 5.9 7.1 4.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG80605.1 - 7.8e-06 26.1 6.3 0.0023 18.2 0.0 4.2 4 0 0 4 4 4 2 Retrotransposon gag protein Fib_alpha PF08702.10 GBG80605.1 - 0.014 15.6 3.5 0.1 12.8 0.3 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 GBG80605.1 - 0.03 14.7 0.4 0.03 14.7 0.4 3.2 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 GBG80605.1 - 7 6.7 9.0 2.2 8.3 0.6 3.0 3 1 0 3 3 3 0 Laminin Domain II RVT_1 PF00078.27 GBG80606.1 - 1.4e-25 90.2 0.1 2e-25 89.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80606.1 - 1.5e-15 57.0 0.0 4.1e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80606.1 - 2.8e-07 30.8 0.0 7.8e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TPT PF03151.16 GBG80607.1 - 4.2e-07 29.6 14.8 5.7e-07 29.2 14.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG80607.1 - 0.051 13.8 29.3 0.73 10.0 9.3 2.4 2 1 0 2 2 2 0 EamA-like transporter family RVT_1 PF00078.27 GBG80608.1 - 4.3e-30 104.9 0.1 6.4e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80608.1 - 3e-06 27.8 0.0 6.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80608.1 - 8.9e-05 23.0 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80608.1 - 0.0026 17.6 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease ETC_C1_NDUFA5 PF04716.14 GBG80609.1 - 1.1e-24 86.0 0.1 1.6e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Integrase_H2C2 PF17921.1 GBG80610.1 - 4.3e-12 46.0 0.6 8.5e-12 45.0 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80610.1 - 4.4e-11 43.0 0.0 9.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG80611.1 - 1.8e-37 129.0 0.7 3.4e-37 128.1 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AhpC-TSA PF00578.21 GBG80613.1 - 3.3e-20 72.2 0.0 2.2e-19 69.6 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family rve PF00665.26 GBG80613.1 - 7.2e-16 58.5 0.0 1.9e-15 57.1 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Redoxin PF08534.10 GBG80613.1 - 1.5e-10 40.9 0.0 8.8e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Redoxin US2 PF02476.15 GBG80613.1 - 0.0065 17.2 0.0 0.012 16.3 0.0 1.5 1 1 0 1 1 1 1 US2 family AhpC-TSA_2 PF13911.6 GBG80613.1 - 0.052 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme gag-asp_proteas PF13975.6 GBG80614.1 - 0.00017 22.1 0.0 0.00039 20.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG80614.1 - 0.00043 20.5 0.0 0.0012 19.1 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80614.1 - 0.0039 17.8 0.0 0.0077 16.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80614.1 - 0.036 13.9 0.1 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease TRAPP PF04051.16 GBG80615.1 - 3.6e-44 150.0 0.0 4.1e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RVT_1 PF00078.27 GBG80616.1 - 1.6e-34 119.3 0.2 3.5e-34 118.3 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80616.1 - 9e-29 99.5 0.0 5.9e-28 96.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80616.1 - 2e-24 85.9 0.0 5.8e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Helo_like_N PF17111.5 GBG80617.1 - 0.016 14.6 1.2 0.037 13.4 1.2 1.5 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins RVT_1 PF00078.27 GBG80618.1 - 0.00036 20.1 0.0 0.00061 19.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACT_3 PF10000.9 GBG80618.1 - 0.049 13.6 0.1 0.19 11.7 0.1 2.0 1 0 0 1 1 1 0 ACT domain RT_RNaseH_2 PF17919.1 GBG80619.1 - 6.1e-23 80.8 0.0 1.3e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80619.1 - 2.6e-20 72.7 0.0 2.9e-19 69.3 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80619.1 - 5.3e-09 36.3 0.0 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.20 GBG80619.1 - 0.0055 17.0 0.1 0.016 15.5 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 GBG80619.1 - 0.007 16.1 0.0 0.03 14.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG80619.1 - 0.028 14.7 0.4 3.2 8.1 0.0 2.9 2 1 0 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG80619.1 - 0.039 14.6 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG80619.1 - 0.047 13.5 0.2 0.076 12.9 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG80619.1 - 0.12 13.0 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ku_N PF03731.15 GBG80619.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain Retrotrans_gag PF03732.17 GBG80620.1 - 0.003 17.8 0.2 0.021 15.1 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG80621.1 - 9.8e-21 73.7 0.0 2.1e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80621.1 - 1.4e-18 67.1 0.0 1.1e-17 64.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80621.1 - 8.6e-08 32.4 0.0 1.9e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG80621.1 - 0.012 15.1 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG80621.1 - 0.13 12.6 0.0 0.47 10.8 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG80622.1 - 2.2e-24 85.4 0.0 4e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80622.1 - 4.1e-24 84.9 0.0 6.8e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80622.1 - 6.7e-22 78.1 0.2 1.3e-20 73.9 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAUS6_N PF14661.6 GBG80623.1 - 9.2 5.8 26.2 0.043 13.4 5.8 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus RVT_1 PF00078.27 GBG80624.1 - 4e-30 105.0 0.0 7.4e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80624.1 - 5.2e-26 90.6 0.0 1.6e-25 89.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80624.1 - 5.5e-20 71.6 0.0 1.6e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80624.1 - 2.4e-09 37.4 0.1 1.1e-08 35.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain TAF4 PF05236.14 GBG80624.1 - 0.043 13.6 8.4 0.077 12.7 8.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family FAM76 PF16046.5 GBG80624.1 - 0.13 11.6 9.7 0.29 10.5 9.7 1.5 1 0 0 1 1 1 0 FAM76 protein Retrotrans_gag PF03732.17 GBG80625.1 - 0.00024 21.3 1.1 0.00086 19.5 0.5 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein Senescence_reg PF04520.13 GBG80625.1 - 0.034 15.0 3.3 0.047 14.5 2.2 1.8 2 0 0 2 2 2 0 Senescence regulator RT_RNaseH_2 PF17919.1 GBG80626.1 - 1.1e-22 79.9 0.0 2.1e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80626.1 - 4.6e-20 71.9 0.0 1e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80626.1 - 1.3e-13 50.8 0.0 3.2e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80626.1 - 4.9e-13 49.3 0.0 1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG80626.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG80628.1 - 2.3e-27 95.9 0.3 4e-22 78.8 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80628.1 - 1.3e-23 82.9 0.0 4.8e-23 81.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80628.1 - 4.8e-22 78.2 0.0 3.2e-21 75.6 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80628.1 - 9.6e-09 35.4 9.7 0.0023 18.1 0.3 5.3 4 0 0 4 4 4 2 Retrotransposon gag protein rve PF00665.26 GBG80628.1 - 4.8e-05 23.5 0.0 0.00016 21.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG80628.1 - 0.00038 20.3 0.0 0.00086 19.2 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG80628.1 - 0.023 14.4 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease FlxA PF14282.6 GBG80628.1 - 0.082 12.9 0.1 0.082 12.9 0.1 5.2 5 1 1 6 6 6 0 FlxA-like protein RT_RNaseH PF17917.1 GBG80629.1 - 2.6e-23 82.3 0.0 8.5e-23 80.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80629.1 - 7.5e-22 77.3 0.0 2.3e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80629.1 - 9.7e-10 38.3 0.2 3.8e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80629.1 - 1.8e-09 37.8 0.3 9.4e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG80629.1 - 0.00081 19.6 0.2 0.0049 17.1 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein Tudor-knot PF11717.8 GBG80629.1 - 0.0024 17.7 0.0 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain ORC6 PF05460.13 GBG80630.1 - 4.6e-11 42.6 0.1 5e-11 42.5 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Integrase_H2C2 PF17921.1 GBG80631.1 - 5e-15 55.4 0.8 1.5e-14 53.8 0.8 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1712 PF08217.11 GBG80631.1 - 5.9e-07 28.4 0.0 0.015 13.8 0.0 2.1 1 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) rve PF00665.26 GBG80631.1 - 0.0011 19.1 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80631.1 - 0.058 13.6 0.2 0.36 11.1 0.0 2.3 2 0 0 2 2 2 0 H2C2 zinc finger RVT_1 PF00078.27 GBG80632.1 - 2.5e-40 138.3 3.2 5.9e-28 97.9 0.1 2.6 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80632.1 - 1.4e-33 114.9 0.1 4.2e-15 55.6 0.0 3.8 2 1 1 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80632.1 - 6.9e-33 113.1 0.0 1.2e-17 64.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG80632.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG80632.1 - 0.0065 16.5 0.1 0.016 15.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Spc29 PF17082.5 GBG80634.1 - 0.0062 16.4 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 Spindle Pole Component 29 SlyX PF04102.12 GBG80634.1 - 0.01 16.4 0.7 0.01 16.4 0.7 3.6 3 1 1 4 4 4 0 SlyX DUF1664 PF07889.12 GBG80634.1 - 0.049 13.7 1.5 0.26 11.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 GBG80634.1 - 0.12 12.7 1.3 3 8.2 0.0 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein DUF16 PF01519.16 GBG80634.1 - 0.13 12.8 4.0 0.36 11.3 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function DUF16 TolA_bind_tri PF16331.5 GBG80634.1 - 0.19 11.8 8.3 0.03 14.4 3.4 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Baculo_PEP_C PF04513.12 GBG80634.1 - 0.53 10.3 6.3 0.34 10.9 3.9 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 GBG80634.1 - 7.3 6.7 13.2 0.053 13.6 1.1 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF919 PF06034.11 GBG80635.1 - 5.8e-05 22.8 1.6 0.00045 20.0 0.2 2.9 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF919) Nif11 PF07862.11 GBG80635.1 - 4.9 7.5 7.7 0.91 9.9 0.6 3.3 4 1 0 4 4 4 0 Nif11 domain RT_RNaseH_2 PF17919.1 GBG80636.1 - 1.6e-30 105.1 0.0 3.3e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80636.1 - 5.9e-26 91.3 0.1 1.2e-25 90.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80636.1 - 3.2e-25 88.4 0.1 7.6e-25 87.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80636.1 - 8.6e-18 64.2 0.1 2e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80636.1 - 3.7e-15 56.2 0.0 8.5e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80636.1 - 0.0036 17.5 0.2 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG80636.1 - 0.012 16.2 0.0 0.047 14.3 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF3225 PF11533.8 GBG80636.1 - 0.098 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) Asp_protease_2 PF13650.6 GBG80636.1 - 0.21 12.2 0.0 0.47 11.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease APC_N_CC PF16689.5 GBG80636.1 - 1 9.5 3.7 2.4 8.3 0.2 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1712 PF08217.11 GBG80637.1 - 5e-12 45.1 0.0 7.1e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Asp_protease_2 PF13650.6 GBG80637.1 - 0.0041 17.7 0.0 0.008 16.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80637.1 - 0.017 15.7 0.0 0.037 14.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80637.1 - 0.027 14.3 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG80638.1 - 1.9e-30 106.1 0.1 3.2e-30 105.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80638.1 - 1.2e-18 66.9 0.4 1.2e-18 66.9 0.4 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain DUF751 PF05421.11 GBG80638.1 - 9.8e-17 61.4 3.4 2e-16 60.4 3.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF751) RT_RNaseH PF17917.1 GBG80638.1 - 2.8e-10 40.4 0.0 8.4e-10 38.9 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG80638.1 - 8.9e-08 32.7 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80638.1 - 4.1e-07 30.5 0.0 8.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80638.1 - 5.1e-06 26.3 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG80638.1 - 0.00025 21.3 0.4 0.00078 19.7 0.1 2.0 2 0 0 2 2 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG80638.1 - 0.00026 20.8 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG80638.1 - 0.0021 18.0 0.0 0.0068 16.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG80638.1 - 0.029 14.6 0.0 0.11 12.7 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCCH PF00642.24 GBG80639.1 - 5.6e-12 45.3 13.8 3.5e-07 30.0 3.0 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG80639.1 - 5.5e-05 23.1 15.9 0.0091 16.0 2.3 2.6 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 GBG80639.1 - 0.0001 22.0 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 GBG80639.1 - 0.0011 19.6 2.7 0.053 14.2 0.2 2.6 2 0 0 2 2 2 1 Torus domain zf-CCCH_3 PF15663.5 GBG80639.1 - 0.25 11.6 4.2 9 6.6 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 GBG80639.1 - 3.7 7.5 15.5 0.36 10.7 3.5 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger Glyco_transf_25 PF01755.17 GBG80641.1 - 5.7e-27 94.9 0.0 2.6e-17 63.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) EamA PF00892.20 GBG80641.1 - 8.1e-05 22.8 0.6 8.1e-05 22.8 0.6 2.6 2 0 0 2 2 2 1 EamA-like transporter family SDA1 PF05285.12 GBG80641.1 - 0.0031 17.0 0.6 0.0031 17.0 0.6 5.3 6 0 0 6 6 6 1 SDA1 BUD22 PF09073.10 GBG80641.1 - 0.0071 15.7 0.4 0.0071 15.7 0.4 5.9 7 0 0 7 7 7 1 BUD22 PUNUT PF16913.5 GBG80641.1 - 0.02 14.1 0.7 0.036 13.3 0.7 1.3 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport TPT PF03151.16 GBG80641.1 - 0.03 13.7 1.7 0.25 10.6 0.3 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF4366 PF14283.6 GBG80641.1 - 2.5 8.1 11.1 1.7 8.7 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) DUF4746 PF15928.5 GBG80642.1 - 4.1 6.7 5.4 6.6 6.1 4.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) RT_RNaseH_2 PF17919.1 GBG80643.1 - 6.4e-27 93.5 0.0 1.4e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80643.1 - 3.7e-25 88.2 0.0 8.9e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80643.1 - 3.6e-16 59.0 0.6 8.5e-16 57.8 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG80643.1 - 1.7e-06 28.6 0.0 1.2e-05 25.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80643.1 - 2.9e-05 24.5 0.0 8.9e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG80643.1 - 0.00043 19.8 0.2 0.0026 17.3 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80643.1 - 0.0018 18.0 0.0 0.0054 16.5 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80643.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease MAD PF05557.13 GBG80643.1 - 0.26 9.6 7.3 0.5 8.7 7.3 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.11 GBG80643.1 - 0.51 9.2 7.1 1.2 8.0 7.1 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Spectrin PF00435.21 GBG80643.1 - 0.51 10.9 4.3 0.54 10.8 1.8 2.3 1 1 1 2 2 2 0 Spectrin repeat Tropomyosin_1 PF12718.7 GBG80643.1 - 4.2 7.5 7.9 10 6.2 0.0 2.6 2 1 0 2 2 2 0 Tropomyosin like Apolipoprotein PF01442.18 GBG80643.1 - 8.1 6.3 21.2 0.76 9.6 16.1 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF563 PF04577.14 GBG80644.1 - 3.6e-19 69.7 0.0 5.6e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DDE_Tnp_4 PF13359.6 GBG80646.1 - 1.9e-31 108.9 0.0 1.7e-30 105.8 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80646.1 - 3.5e-15 56.2 0.0 6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG80646.1 - 1e-07 31.8 0.2 0.0029 17.3 0.0 3.2 3 0 0 3 3 3 3 Transposase DDE domain RVT_1 PF00078.27 GBG80647.1 - 2.5e-30 105.6 4.3 3.8e-24 85.4 0.1 2.5 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80647.1 - 4.9e-09 36.7 0.0 2.7e-06 27.9 0.0 2.8 3 0 0 3 3 3 2 Aspartyl protease RVP_2 PF08284.11 GBG80647.1 - 6.7e-09 35.6 0.0 0.00035 20.4 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG80647.1 - 2e-07 31.5 0.0 9.5e-06 26.1 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80647.1 - 2.2e-05 24.2 0.0 0.00051 19.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG80648.1 - 3.1e-26 91.3 0.0 7e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80648.1 - 2.6e-24 85.5 0.0 5.5e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG80648.1 - 4.7e-08 33.6 0.0 3.2e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80648.1 - 5e-06 27.0 0.0 1.4e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80648.1 - 1.1e-05 25.2 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80648.1 - 0.0037 17.0 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG80648.1 - 0.048 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG80649.1 - 8.8e-23 80.2 0.0 2.1e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80649.1 - 1.4e-20 73.6 0.0 2.6e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80649.1 - 1.6e-19 69.7 0.2 3.3e-19 68.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80649.1 - 3.9e-19 69.1 0.1 6.7e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG80649.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RR_TM4-6 PF06459.12 GBG80650.1 - 0.011 15.6 12.4 0.018 14.9 12.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 GBG80650.1 - 0.023 14.5 3.7 0.042 13.6 3.7 1.5 1 0 0 1 1 1 0 Coilin N-terminus DDHD PF02862.17 GBG80650.1 - 0.067 13.3 3.2 0.12 12.6 3.2 1.5 1 0 0 1 1 1 0 DDHD domain DUF4746 PF15928.5 GBG80650.1 - 0.12 11.7 5.9 0.19 11.1 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 GBG80650.1 - 0.15 12.0 20.6 0.11 12.5 13.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sin_N PF04801.13 GBG80650.1 - 0.45 9.7 14.7 0.63 9.2 14.7 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region CPSF100_C PF13299.6 GBG80650.1 - 0.86 9.8 6.9 1.9 8.7 6.9 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 GBG80650.1 - 1.6 8.1 6.7 2.5 7.4 6.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_S64 PF08192.11 GBG80650.1 - 2 6.8 10.3 2.5 6.5 10.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 GBG80650.1 - 2.4 6.8 12.7 3.3 6.4 12.7 1.2 1 0 0 1 1 1 0 Presenilin CCDC53 PF10152.9 GBG80650.1 - 2.8 8.4 12.4 7.8 6.9 12.4 1.7 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SLC12 PF03522.15 GBG80650.1 - 3 6.8 8.9 3.9 6.4 8.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 GBG80650.1 - 3.4 6.5 7.3 4.7 6.0 7.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF913 PF06025.12 GBG80650.1 - 6.5 5.6 6.4 11 4.8 6.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 GBG80650.1 - 7.7 5.6 4.9 9.6 5.3 4.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4065 PF13274.6 GBG80652.1 - 0.15 13.0 0.2 0.15 13.0 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4065) Pox_Ag35 PF03286.14 GBG80652.1 - 0.22 11.3 22.5 1.9 8.3 1.4 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein COPI_C PF06957.11 GBG80652.1 - 0.55 8.9 12.9 0.73 8.5 11.8 1.6 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus SpoIIIAH PF12685.7 GBG80652.1 - 8.9 6.1 13.2 4.1 7.2 5.5 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Nop14 PF04147.12 GBG80652.1 - 9.9 4.2 27.3 0.22 9.7 19.6 1.9 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 GBG80653.1 - 1.4 8.1 17.8 0.51 9.6 11.9 2.2 2 0 0 2 2 2 0 BUD22 SURF2 PF05477.11 GBG80653.1 - 4.4 6.9 9.6 3.8 7.1 6.2 2.4 2 1 0 2 2 2 0 Surfeit locus protein 2 (SURF2) SDA1 PF05285.12 GBG80654.1 - 0.0021 17.5 30.6 0.0026 17.2 30.6 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GBG80654.1 - 0.64 9.3 27.8 0.82 8.9 27.8 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG80654.1 - 5.3 5.1 36.1 6.9 4.7 36.1 1.1 1 0 0 1 1 1 0 Nop14-like family LON_substr_bdg PF02190.16 GBG80658.1 - 5e-13 49.4 0.0 5.9e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Protocadherin PF08374.11 GBG80659.1 - 0.21 11.6 1.8 0.47 10.4 1.8 1.5 1 0 0 1 1 1 0 Protocadherin LMBR1 PF04791.16 GBG80659.1 - 0.26 10.1 4.9 0.38 9.6 4.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein PEP-utilisers_N PF05524.13 GBG80659.1 - 0.61 10.3 16.6 0.1 12.8 6.9 2.7 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF5069 PF16798.5 GBG80659.1 - 0.74 10.0 7.3 0.14 12.4 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) Pex24p PF06398.11 GBG80659.1 - 1.6 7.7 6.1 2.9 6.8 6.1 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin RT_RNaseH_2 PF17919.1 GBG80660.1 - 8.2e-22 77.1 0.0 2.4e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80660.1 - 2e-21 76.3 0.1 9.1e-21 74.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80660.1 - 8e-16 58.2 0.6 1.1e-08 34.9 0.2 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80660.1 - 8.2e-07 29.6 0.0 2.2e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80660.1 - 1.2e-06 29.0 0.0 3.4e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG80660.1 - 4.7e-06 26.8 3.4 0.037 14.3 0.1 3.6 3 0 0 3 3 3 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG80660.1 - 2.6e-05 24.0 0.0 7.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80660.1 - 0.00035 20.4 0.0 0.00085 19.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease CENP-K PF11802.8 GBG80660.1 - 0.51 9.9 7.8 0.077 12.6 2.0 2.2 2 0 0 2 2 2 0 Centromere-associated protein K Fez1 PF06818.15 GBG80660.1 - 1.3 9.5 10.8 4.9 7.5 6.1 2.4 2 0 0 2 2 2 0 Fez1 RT_RNaseH_2 PF17919.1 GBG80661.1 - 3.7e-29 100.7 0.0 9.4e-29 99.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80661.1 - 5e-29 100.7 0.0 1.3e-28 99.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80661.1 - 3.5e-10 39.8 0.0 8.9e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA PF00004.29 GBG80661.1 - 1.1e-05 25.8 0.0 4.5e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 GBG80661.1 - 0.0007 18.6 0.0 0.0095 14.9 0.0 2.2 2 0 0 2 2 2 1 PrkA AAA domain Chromo PF00385.24 GBG80661.1 - 0.00091 19.1 0.0 0.0031 17.4 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_5 PF07728.14 GBG80661.1 - 0.0013 18.8 0.0 0.0058 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 GBG80661.1 - 0.0017 18.3 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_16 PF13191.6 GBG80661.1 - 0.0024 18.3 0.1 0.063 13.7 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GBG80661.1 - 0.024 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_3 PF07726.11 GBG80661.1 - 0.055 13.3 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GBG80661.1 - 0.086 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Phage_GPO PF05929.11 GBG80661.1 - 0.19 11.3 0.0 0.19 11.3 0.0 2.8 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG80662.1 - 5e-57 193.0 5.6 5.1e-28 98.1 0.1 3.1 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80662.1 - 7.1e-51 170.4 0.0 6.3e-24 83.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80662.1 - 1.1e-50 170.2 0.0 8.3e-24 83.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80662.1 - 2.3e-17 62.8 0.4 5e-17 61.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG80662.1 - 1.2e-08 34.8 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG80662.1 - 2.5e-08 34.1 0.8 8.2e-08 32.5 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain Asp_protease_2 PF13650.6 GBG80662.1 - 8e-07 29.6 0.0 1.8e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80662.1 - 3e-05 24.5 0.0 6.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG80662.1 - 0.00018 21.3 0.0 0.00054 19.8 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG80662.1 - 0.0025 17.6 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF3806 PF12713.7 GBG80662.1 - 0.0038 17.0 0.0 5.3 6.9 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3806) Integrin_b_cyt PF08725.11 GBG80662.1 - 0.017 14.8 0.1 9.5 6.0 0.0 2.7 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Occludin_ELL PF07303.13 GBG80662.1 - 0.03 15.0 2.2 15 6.4 0.2 3.4 2 0 0 2 2 2 0 Occludin homology domain P4Ha_N PF08336.11 GBG80662.1 - 0.044 13.8 0.7 15 5.6 0.1 2.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3510 PF12022.8 GBG80662.1 - 0.046 14.1 2.8 10 6.5 0.0 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF3510) Chromo PF00385.24 GBG80662.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG80663.1 - 4e-20 71.7 0.3 4e-20 71.7 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG80663.1 - 1.2e-19 70.6 0.2 2e-19 69.8 0.2 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80663.1 - 3.8e-14 52.5 0.1 7.2e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80663.1 - 0.0012 19.0 0.0 0.005 17.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG80663.1 - 0.0068 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Lon_C PF05362.13 GBG80664.1 - 1.9e-77 259.5 1.9 2.8e-77 258.9 1.9 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 GBG80664.1 - 1.7e-07 31.7 0.0 3.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 GBG80664.1 - 2.6e-07 30.5 0.0 6.7e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase RVT_1 PF00078.27 GBG80665.1 - 1.4e-28 99.9 1.3 3.9e-28 98.5 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80665.1 - 6e-10 39.1 0.0 1.4e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80665.1 - 1.8e-09 37.7 1.6 0.054 13.8 0.1 4.1 3 0 0 3 3 3 3 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG80665.1 - 0.046 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80667.1 - 3.5e-17 62.7 0.0 5.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_6 PF15288.6 GBG80667.1 - 0.057 13.3 0.3 0.14 12.0 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle PET PF06297.14 GBG80667.1 - 0.078 13.3 0.5 0.73 10.2 0.3 2.7 3 0 0 3 3 3 0 PET Domain Retrotrans_gag PF03732.17 GBG80667.1 - 0.082 13.2 0.1 0.4 11.0 0.1 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG80667.1 - 0.12 12.5 3.7 0.2 11.8 3.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG80667.1 - 0.15 11.8 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG80668.1 - 6.5e-26 91.2 0.0 1.2e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80668.1 - 7.6e-18 64.4 0.0 1.9e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80668.1 - 5.6e-10 39.4 0.0 1.5e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG80668.1 - 2.2e-06 27.5 0.0 4.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80668.1 - 2.5e-06 28.0 0.0 4.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80668.1 - 0.00049 20.6 0.0 0.001 19.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG80668.1 - 0.0068 16.3 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG80668.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.12 GBG80669.1 - 0.0027 18.3 0.2 0.0027 18.3 0.2 2.9 3 1 0 3 3 3 1 SlyX RVT_1 PF00078.27 GBG80670.1 - 1.7e-26 93.2 0.1 3.4e-26 92.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80670.1 - 2e-16 59.8 0.3 3.8e-16 58.9 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG80670.1 - 1.7e-15 56.9 0.0 4.5e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80670.1 - 1.2e-10 41.6 0.0 4.3e-07 30.2 0.0 2.8 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG80670.1 - 3.6e-05 23.5 0.2 0.00022 20.9 0.0 2.4 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.17 GBG80670.1 - 0.00053 20.2 0.2 0.0022 18.3 0.2 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein WD40 PF00400.32 GBG80672.1 - 4.2e-11 43.2 0.3 10 7.2 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40 PF00400.32 GBG80673.1 - 4.1e-11 43.2 0.3 10 7.2 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat DDE_Tnp_4 PF13359.6 GBG80675.1 - 1.2e-05 25.0 0.2 2e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Rxt3 PF08642.10 GBG80676.1 - 3 8.6 5.8 0.82 10.5 1.8 2.1 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Met_gamma_lyase PF06838.11 GBG80677.1 - 2.8e-167 556.3 0.0 3.5e-167 556.0 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Cys_Met_Meta_PP PF01053.20 GBG80677.1 - 7.7e-10 37.8 0.0 1.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GBG80677.1 - 3.5e-07 29.7 0.0 6.5e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GBG80677.1 - 0.038 12.9 0.0 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V RVT_1 PF00078.27 GBG80678.1 - 3.8e-36 124.7 0.0 1.6e-35 122.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIA PF03153.13 GBG80678.1 - 0.22 11.5 18.4 0.34 10.8 18.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Polyketide_cyc PF03364.20 GBG80680.1 - 3.6e-15 56.3 0.0 6.2e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GBG80680.1 - 5.6e-06 26.7 1.0 7.2e-06 26.3 0.1 1.7 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 GBG80680.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) rve PF00665.26 GBG80682.1 - 6.6e-09 36.0 0.0 1.5e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG80682.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DAGAT PF03982.13 GBG80683.1 - 0.1 11.5 1.1 5 5.9 0.2 2.1 1 1 1 2 2 2 0 Diacylglycerol acyltransferase RT_RNaseH_2 PF17919.1 GBG80684.1 - 2.2e-27 95.0 0.0 4e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80684.1 - 3.6e-24 85.1 0.0 8.9e-24 83.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80684.1 - 1.2e-10 41.3 0.1 2.1e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG80684.1 - 0.82 7.8 7.8 1.1 7.4 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG80684.1 - 0.89 7.8 10.1 1.3 7.3 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein HATPase_c PF02518.26 GBG80685.1 - 3e-27 95.3 0.0 8.2e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GBG80685.1 - 5.9e-20 71.5 0.1 4.6e-15 55.7 0.1 3.1 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 GBG80685.1 - 7.5e-15 54.7 1.8 1.5e-14 53.8 0.1 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Dynamin_N PF00350.23 GBG80685.1 - 0.11 12.5 0.3 0.31 11.1 0.3 1.8 1 0 0 1 1 1 0 Dynamin family TIMELESS PF04821.14 GBG80685.1 - 0.87 8.8 9.2 2.2 7.5 9.2 1.6 1 0 0 1 1 1 0 Timeless protein Eapp_C PF10238.9 GBG80685.1 - 8.5 6.4 7.1 28 4.8 4.8 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein rve PF00665.26 GBG80686.1 - 7.9e-10 39.0 0.0 2.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG80686.1 - 0.05 13.5 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF3801 PF12687.7 GBG80686.1 - 2.2 8.3 8.3 5.7 7.0 8.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DnaJ PF00226.31 GBG80688.1 - 3.6e-09 36.6 0.0 6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Fer4_15 PF13459.6 GBG80688.1 - 0.0017 19.0 0.8 0.0039 17.9 0.8 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 GBG80688.1 - 0.0063 17.0 0.7 0.014 15.9 0.7 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I zf-CCHC PF00098.23 GBG80689.1 - 1e-05 25.3 1.6 2.4e-05 24.2 1.6 1.7 1 0 0 1 1 1 1 Zinc knuckle RNA_pol_Rpc4 PF05132.14 GBG80689.1 - 0.1 13.0 3.2 0.089 13.2 1.6 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 zf-CCHC_2 PF13696.6 GBG80689.1 - 0.39 10.6 3.0 0.76 9.7 3.0 1.5 1 0 0 1 1 1 0 Zinc knuckle hDGE_amylase PF14701.6 GBG80689.1 - 0.42 9.6 2.3 0.59 9.2 2.3 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF3464 PF11947.8 GBG80689.1 - 1.4 8.7 6.2 2.5 7.8 6.2 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Porin_5 PF16930.5 GBG80689.1 - 6 5.2 6.0 8.6 4.7 6.0 1.1 1 0 0 1 1 1 0 Putative porin zf-TRAF PF02176.18 GBG80692.1 - 9.7e-14 51.8 7.1 2.8e-08 34.3 2.0 3.2 2 0 0 2 2 2 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 GBG80692.1 - 7.8e-08 32.1 6.0 7.8e-08 32.1 6.0 2.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG80692.1 - 6.8e-07 29.0 6.3 6.8e-07 29.0 6.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG80692.1 - 2.2e-06 27.9 6.7 2.2e-06 27.9 6.7 3.5 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG80692.1 - 1.5e-05 24.7 6.8 1.5e-05 24.7 6.8 3.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG80692.1 - 1.7e-05 24.7 1.4 1.7e-05 24.7 1.4 3.8 4 1 0 4 4 4 1 RING-type zinc-finger zf-TRAF_2 PF15965.5 GBG80692.1 - 8.9e-05 22.9 20.4 0.00036 20.9 2.2 3.1 2 1 1 3 3 2 2 TRAF-like zinc-finger Prok-RING_4 PF14447.6 GBG80692.1 - 0.00018 21.3 6.0 0.00018 21.3 6.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GBG80692.1 - 0.00028 20.8 6.8 0.00028 20.8 6.8 2.8 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GBG80692.1 - 0.0013 18.8 8.7 0.0013 18.8 8.7 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 GBG80692.1 - 0.0071 16.3 1.2 0.017 15.1 1.2 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 GBG80692.1 - 0.0072 16.4 0.5 0.021 14.8 0.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Sina PF03145.16 GBG80692.1 - 0.0094 15.9 9.2 0.36 10.7 2.2 2.5 2 0 0 2 2 2 2 Seven in absentia protein family zf-rbx1 PF12678.7 GBG80692.1 - 0.014 15.6 3.4 0.014 15.6 3.4 2.8 3 1 0 3 3 2 0 RING-H2 zinc finger domain YdjO PF14169.6 GBG80692.1 - 0.93 9.3 5.0 5.1 6.9 4.3 2.5 1 1 1 2 2 2 0 Cold-inducible protein YdjO zf-U11-48K PF05253.12 GBG80692.1 - 0.94 9.5 5.7 19 5.3 0.0 4.4 5 0 0 5 5 5 0 U11-48K-like CHHC zinc finger DM PF00751.18 GBG80692.1 - 1.2 9.1 7.4 1.5 8.8 0.2 3.4 3 0 0 3 3 2 0 DM DNA binding domain zf-RING_6 PF14835.6 GBG80692.1 - 1.3 8.9 6.3 0.78 9.7 3.1 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 GBG80692.1 - 3.5 7.5 17.2 0.042 13.6 6.4 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 GBG80692.1 - 5.3 7.3 11.8 0.076 13.2 3.9 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-CCHC PF00098.23 GBG80693.1 - 4.8e-05 23.2 3.7 8.8e-05 22.4 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG80693.1 - 0.092 12.5 0.4 0.29 10.9 0.4 1.9 1 0 0 1 1 1 0 Zinc knuckle YlbD_coat PF14071.6 GBG80693.1 - 0.14 12.4 8.3 2 8.7 1.8 2.6 1 1 1 2 2 2 0 Putative coat protein EMC3_TMCO1 PF01956.16 GBG80693.1 - 2.2 8.0 7.0 3.8 7.2 7.0 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Flu_NS2 PF00601.19 GBG80693.1 - 2.8 8.3 10.3 3.4 8.0 7.6 2.3 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) Atg14 PF10186.9 GBG80693.1 - 7.9 5.5 14.1 11 5.0 14.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Methyltransf_15 PF09445.10 GBG80694.1 - 6.5e-43 146.2 0.0 1e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 GBG80694.1 - 2.9e-08 33.7 0.0 5.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 GBG80694.1 - 5.2e-07 30.3 0.0 1.4e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GBG80694.1 - 9.4e-07 28.7 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 GBG80694.1 - 5.5e-06 26.2 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GBG80694.1 - 6.5e-05 22.7 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 WW PF00397.26 GBG80694.1 - 7.7e-05 22.7 8.2 0.00017 21.6 8.2 1.6 1 0 0 1 1 1 1 WW domain Methyltransf_11 PF08241.12 GBG80694.1 - 0.0007 20.2 0.0 0.0019 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG80694.1 - 0.0033 17.0 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 GBG80694.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 GBG80694.1 - 0.018 14.5 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 GBG80694.1 - 0.07 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_15 PF09445.10 GBG80695.1 - 7.7e-43 145.9 0.0 1.2e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 GBG80695.1 - 3.3e-08 33.5 0.0 6.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 GBG80695.1 - 6.1e-07 30.1 0.0 1.7e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GBG80695.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 GBG80695.1 - 6.5e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GBG80695.1 - 7.5e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 WW PF00397.26 GBG80695.1 - 9e-05 22.5 8.2 0.0002 21.4 8.2 1.6 1 0 0 1 1 1 1 WW domain Methyltransf_11 PF08241.12 GBG80695.1 - 0.00083 20.0 0.0 0.0023 18.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG80695.1 - 0.0039 16.8 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 GBG80695.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 GBG80695.1 - 0.021 14.2 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 GBG80695.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RVT_1 PF00078.27 GBG80696.1 - 3.7e-31 108.4 0.0 5.8e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80696.1 - 1.9e-16 59.9 0.5 6.8e-16 58.1 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG80696.1 - 2.2e-15 56.5 0.0 5.2e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80696.1 - 1.5e-11 44.5 0.4 9.7e-11 41.9 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.24 GBG80696.1 - 1.6e-11 43.9 0.0 3.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG80696.1 - 2.2e-05 24.5 0.0 5.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG80696.1 - 0.001 19.3 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG80697.1 - 6.4e-12 45.2 0.0 1.5e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG80697.1 - 5.7e-11 42.7 0.1 3.4e-10 40.1 0.1 2.1 2 0 0 2 2 2 1 Integrase core domain DUF1664 PF07889.12 GBG80698.1 - 3e-41 140.3 1.6 7.7e-40 135.8 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) FlxA PF14282.6 GBG80698.1 - 0.00012 22.0 4.7 0.034 14.1 0.3 2.4 2 0 0 2 2 2 2 FlxA-like protein YlqD PF11068.8 GBG80698.1 - 0.00013 22.4 8.8 0.047 14.1 3.1 2.4 2 0 0 2 2 2 2 YlqD protein Apolipoprotein PF01442.18 GBG80698.1 - 0.0002 21.3 5.6 0.0024 17.8 0.7 2.2 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain SseC PF04888.12 GBG80698.1 - 0.00064 19.4 4.3 0.00088 19.0 4.3 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family THOC7 PF05615.13 GBG80698.1 - 0.00082 19.7 0.4 0.0015 18.8 0.4 1.4 1 1 0 1 1 1 1 Tho complex subunit 7 Spc7 PF08317.11 GBG80698.1 - 0.0014 17.6 4.9 0.0018 17.3 1.6 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Filament PF00038.21 GBG80698.1 - 0.0075 15.9 0.5 0.0075 15.9 0.5 1.9 2 0 0 2 2 2 1 Intermediate filament protein DUF948 PF06103.11 GBG80698.1 - 0.011 15.9 7.5 0.31 11.3 2.1 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CdvA PF18822.1 GBG80698.1 - 0.013 15.3 6.5 0.27 11.1 0.3 2.8 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Baculo_PEP_C PF04513.12 GBG80698.1 - 0.015 15.4 6.1 0.35 10.9 1.3 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GCN5L1 PF06320.13 GBG80698.1 - 0.038 14.1 4.9 0.37 10.9 0.9 2.7 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) ACP PF06857.11 GBG80698.1 - 0.056 13.7 2.1 0.37 11.1 0.3 2.7 2 1 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) Matrilin_ccoil PF10393.9 GBG80698.1 - 0.058 13.3 10.3 12 5.8 0.1 4.3 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4407 PF14362.6 GBG80698.1 - 0.073 12.4 2.3 0.19 11.0 1.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 GBG80698.1 - 0.078 13.5 7.1 0.082 13.4 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 COG2 PF06148.11 GBG80698.1 - 0.095 12.8 8.3 0.21 11.7 1.3 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Snapin_Pallidin PF14712.6 GBG80698.1 - 0.11 13.0 7.0 1.2 9.6 2.3 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Erp_C PF06780.11 GBG80698.1 - 0.12 12.4 1.5 0.15 12.1 0.4 1.6 2 0 0 2 2 1 0 Erp protein C-terminus Noelin-1 PF12308.8 GBG80698.1 - 0.14 12.2 5.2 0.87 9.6 0.2 3.3 2 1 1 3 3 3 0 Neurogenesis glycoprotein TMF_TATA_bd PF12325.8 GBG80698.1 - 0.18 12.0 8.8 1.9 8.7 2.3 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding LPP PF04728.13 GBG80698.1 - 0.24 11.8 3.1 9.6 6.7 0.1 3.0 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DUF2203 PF09969.9 GBG80698.1 - 0.25 12.1 1.6 2.9 8.6 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Atg14 PF10186.9 GBG80698.1 - 0.26 10.3 2.9 0.12 11.4 0.4 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HemX PF04375.14 GBG80698.1 - 0.27 10.5 5.0 0.35 10.1 0.1 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4600 PF15372.6 GBG80698.1 - 0.44 11.0 3.2 1.4 9.4 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Prominin PF05478.11 GBG80698.1 - 0.45 8.4 3.1 0.66 7.9 0.7 1.9 2 0 0 2 2 2 0 Prominin APG17 PF04108.12 GBG80698.1 - 0.57 9.2 8.2 3.5 6.6 0.7 2.2 1 1 0 2 2 2 0 Autophagy protein Apg17 Fib_alpha PF08702.10 GBG80698.1 - 0.6 10.3 5.6 1.5 9.0 0.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 GBG80698.1 - 1 6.8 5.4 9.6 3.6 5.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) YabA PF06156.13 GBG80698.1 - 1 10.0 5.1 3.3 8.4 1.6 2.7 2 1 0 2 2 2 0 Initiation control protein YabA KxDL PF10241.9 GBG80698.1 - 1.1 9.5 7.5 0.4 11.0 1.1 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 GBG80698.1 - 1.2 9.7 4.5 5.2 7.7 2.2 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CENP-K PF11802.8 GBG80698.1 - 1.3 8.5 6.3 1.8 8.1 2.4 2.1 2 0 0 2 2 2 0 Centromere-associated protein K Syntaxin_2 PF14523.6 GBG80698.1 - 1.4 9.3 5.5 1.8 9.0 0.1 2.8 3 1 0 3 3 2 0 Syntaxin-like protein SlyX PF04102.12 GBG80698.1 - 1.6 9.4 9.6 2.5 8.8 1.0 3.3 3 0 0 3 3 3 0 SlyX Laminin_II PF06009.12 GBG80698.1 - 1.6 8.7 7.1 2.3 8.2 2.1 2.7 2 1 0 2 2 2 0 Laminin Domain II DUF4795 PF16043.5 GBG80698.1 - 2 8.0 6.1 1.3 8.6 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) T7SS_ESX_EspC PF10824.8 GBG80698.1 - 3.2 8.3 7.3 5.7 7.5 1.7 2.7 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DUF4746 PF15928.5 GBG80701.1 - 0.012 15.1 1.0 0.044 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RT_RNaseH_2 PF17919.1 GBG80702.1 - 2.3e-23 82.1 0.1 6.9e-23 80.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80702.1 - 9.1e-23 80.5 0.0 3.4e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80702.1 - 3.5e-06 27.2 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF4187 PF13821.6 GBG80702.1 - 0.0038 17.0 1.2 0.011 15.5 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG80702.1 - 0.017 15.4 0.2 0.017 15.4 0.2 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein CoA_binding_3 PF13727.6 GBG80704.1 - 0.0015 18.6 0.6 0.0051 16.9 0.2 2.0 2 0 0 2 2 2 1 CoA-binding domain Peptidase_M56 PF05569.11 GBG80704.1 - 0.096 11.9 0.2 0.096 11.9 0.2 2.1 1 1 1 2 2 2 0 BlaR1 peptidase M56 DUF2530 PF10745.9 GBG80704.1 - 0.2 11.9 5.4 0.44 10.8 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DUF4040 PF13244.6 GBG80704.1 - 0.35 11.1 6.1 0.71 10.1 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) TMP_2 PF06791.13 GBG80704.1 - 3.1 7.4 8.3 0.87 9.2 4.6 1.8 1 1 1 2 2 2 0 Prophage tail length tape measure protein Zn_ribbon_2 PF12674.7 GBG80705.1 - 0.15 12.7 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain CBP_BcsG PF11658.8 GBG80706.1 - 0.13 10.6 6.9 0.031 12.7 4.1 1.3 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF2076 PF09849.9 GBG80706.1 - 1.6 8.7 13.5 2.6 8.0 13.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NOA36 PF06524.12 GBG80706.1 - 2.2 7.5 18.2 2.7 7.2 18.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3995 PF13160.6 GBG80706.1 - 2.4 8.5 8.4 2.8 8.3 7.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3995) DUF1345 PF07077.11 GBG80706.1 - 5.6 6.6 18.5 2.4 7.9 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) PPP4R2 PF09184.11 GBG80706.1 - 6.6 6.2 11.1 8.3 5.9 11.1 1.2 1 0 0 1 1 1 0 PPP4R2 LMF1 PF06762.14 GBG80706.1 - 8 5.4 13.8 9.5 5.2 13.8 1.1 1 0 0 1 1 1 0 Lipase maturation factor F-box-like PF12937.7 GBG80708.1 - 0.00025 20.9 0.4 0.00057 19.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG80708.1 - 0.0003 20.6 0.5 0.0014 18.5 0.5 2.2 1 0 0 1 1 1 1 F-box domain PC-Esterase PF13839.6 GBG80710.1 - 1.2e-43 149.9 0.0 1.8e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 GBG80710.1 - 2e-15 56.8 5.2 2e-15 56.8 5.2 2.0 2 0 0 2 2 2 1 PMR5 N terminal Domain Retrotrans_gag PF03732.17 GBG80710.1 - 1.6e-05 25.1 2.6 0.00011 22.4 0.5 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4288 PF14119.6 GBG80710.1 - 0.12 12.8 4.8 0.27 11.6 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) PC-Esterase PF13839.6 GBG80711.1 - 1.2e-43 149.9 0.0 1.8e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 GBG80711.1 - 2e-15 56.8 5.2 2e-15 56.8 5.2 2.0 2 0 0 2 2 2 1 PMR5 N terminal Domain Retrotrans_gag PF03732.17 GBG80711.1 - 1.6e-05 25.1 2.6 0.00011 22.4 0.5 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4288 PF14119.6 GBG80711.1 - 0.12 12.8 4.8 0.27 11.6 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) CH PF00307.31 GBG80712.1 - 1.3e-12 47.8 0.0 1.8e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain SAM_1 PF00536.30 GBG80713.1 - 7.9e-15 55.0 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GBG80713.1 - 1.2e-11 44.6 0.0 2.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Spt20 PF12090.8 GBG80713.1 - 0.014 15.0 21.3 0.025 14.2 21.3 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 GBG80713.1 - 0.39 10.7 19.0 0.08 12.9 14.9 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 GBG80713.1 - 0.52 9.0 4.0 0.82 8.4 4.0 1.2 1 0 0 1 1 1 0 Presenilin DUF5327 PF17261.2 GBG80713.1 - 0.75 10.6 14.2 2 9.2 14.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Roughex PF06020.11 GBG80713.1 - 0.83 8.7 5.7 1.5 7.9 5.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 GBG80713.1 - 1.9 9.5 10.0 6.8 7.7 10.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-CCHC PF00098.23 GBG80714.1 - 3.9e-05 23.5 0.3 3.9e-05 23.5 0.3 2.4 3 0 0 3 3 3 1 Zinc knuckle DUF2828 PF11443.8 GBG80714.1 - 1.6 6.7 9.4 2.3 6.2 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) K_channel_TID PF07941.11 GBG80715.1 - 0.0051 17.2 18.5 0.0051 17.2 18.5 4.3 5 2 1 6 6 6 1 Potassium channel Kv1.4 tandem inactivation domain KH_1 PF00013.29 GBG80716.1 - 3e-07 30.1 1.3 7.2e-07 28.9 1.3 1.7 1 0 0 1 1 1 1 KH domain Collagen PF01391.18 GBG80716.1 - 0.00035 20.3 11.8 0.00035 20.3 11.8 3.6 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) zf-CCHC_2 PF13696.6 GBG80716.1 - 0.002 17.9 1.3 0.0034 17.2 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF2345 PF10106.9 GBG80716.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) zf-CCHC PF00098.23 GBG80716.1 - 0.082 13.0 0.4 0.17 12.0 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 GBG80716.1 - 0.089 13.2 0.2 0.089 13.2 0.2 2.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G HEAT PF02985.22 GBG80717.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 HEAT repeat CLASP_N PF12348.8 GBG80718.1 - 1.5e-11 44.3 0.0 1.9e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal VHS PF00790.19 GBG80718.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 VHS domain RVT_1 PF00078.27 GBG80719.1 - 1.2e-37 129.6 0.1 3.7e-31 108.4 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80719.1 - 3.3e-25 88.4 0.7 9.3e-25 86.9 0.7 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80719.1 - 2.2e-18 66.2 0.1 5.6e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80719.1 - 5e-14 52.5 0.8 1.6e-13 50.9 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain zf-CCHC PF00098.23 GBG80719.1 - 0.0015 18.5 3.6 0.78 9.9 0.1 2.6 2 0 0 2 2 2 2 Zinc knuckle RVT_1 PF00078.27 GBG80720.1 - 1.2e-54 185.2 2.5 4.9e-27 94.9 0.3 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80720.1 - 1e-25 89.7 0.0 3.6e-25 87.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80720.1 - 1e-21 77.3 0.3 5.8e-14 52.3 0.1 2.7 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH PF17917.1 GBG80720.1 - 3.3e-21 75.6 0.0 1.5e-20 73.5 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CLASP_N PF12348.8 GBG80720.1 - 0.0023 17.5 0.5 0.011 15.3 0.1 2.3 2 0 0 2 2 2 1 CLASP N terminal DUF4543 PF15076.6 GBG80720.1 - 0.0094 16.1 0.2 0.94 9.7 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4543) QVR PF17064.5 GBG80721.1 - 0.048 13.9 0.9 0.14 12.5 0.9 1.8 1 0 0 1 1 1 0 Sleepless protein DivIC PF04977.15 GBG80721.1 - 5.3 6.9 24.2 0.13 12.1 4.7 4.0 3 1 0 3 3 3 0 Septum formation initiator RT_RNaseH PF17917.1 GBG80723.1 - 3.2e-20 72.4 0.0 1.3e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80723.1 - 8e-20 70.7 0.0 1.8e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80723.1 - 8.7e-16 57.8 0.1 3.4e-15 55.9 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG80723.1 - 1.6e-08 34.3 0.0 3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG80723.1 - 0.00029 21.0 0.0 0.00092 19.4 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF659 PF04937.15 GBG80724.1 - 6.5e-07 29.3 0.1 1.2e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80724.1 - 0.00031 20.5 0.1 0.0007 19.3 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH PF17917.1 GBG80725.1 - 1.3e-20 73.6 0.0 7e-20 71.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80725.1 - 8.9e-19 67.4 0.0 4.5e-17 61.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG80725.1 - 6.8e-11 42.6 0.0 2.4e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80725.1 - 1.3e-07 32.1 0.0 3.2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG80725.1 - 8.4e-05 22.8 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80725.1 - 0.0041 16.9 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.8 GBG80725.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon peptidase CENP-F_leu_zip PF10473.9 GBG80725.1 - 1.1 9.3 5.5 0.35 10.9 1.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RVT_1 PF00078.27 GBG80728.1 - 1.6e-22 80.2 0.1 3.3e-22 79.1 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSCB_C PF07743.13 GBG80729.1 - 5.6e-07 30.0 1.0 5.6e-07 30.0 1.0 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain tRNA-synt_1 PF00133.22 GBG80730.1 - 1.7e-206 687.1 0.0 3.3e-205 682.9 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GBG80730.1 - 1.2e-37 129.2 0.0 1.2e-37 129.2 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GBG80730.1 - 2.2e-14 53.0 0.9 4.8e-07 28.9 0.0 4.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GBG80730.1 - 3.4e-10 39.8 0.0 2.8e-08 33.5 0.0 2.6 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 GBG80730.1 - 1.8e-06 28.1 1.1 1.8e-06 28.1 1.1 2.6 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 GBG80730.1 - 2.6e-05 23.7 0.0 0.031 13.6 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain RCDG1 PF15725.5 GBG80730.1 - 0.041 14.3 1.9 0.67 10.4 1.6 2.6 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein ABC_tran PF00005.27 GBG80731.1 - 2.9e-23 82.9 0.0 7.5e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 GBG80731.1 - 0.0012 18.7 0.1 0.003 17.5 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 GBG80731.1 - 0.0044 16.9 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GBG80731.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GBG80731.1 - 0.025 14.3 0.1 0.093 12.5 0.1 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_A24 PF01478.18 GBG80731.1 - 0.025 15.0 1.6 0.038 14.4 0.1 2.1 2 0 0 2 2 2 0 Type IV leader peptidase family SMC_N PF02463.19 GBG80731.1 - 0.064 12.7 0.0 6.7 6.1 0.0 2.3 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 GBG80731.1 - 0.12 12.1 0.3 0.26 11.0 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GBG80731.1 - 0.2 11.8 1.3 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Topo_Zn_Ribbon PF08272.11 GBG80732.1 - 0.12 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG80732.1 - 0.42 10.8 1.7 1 9.6 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle HIP1_clath_bdg PF16515.5 GBG80736.1 - 0.017 15.7 3.7 0.017 15.7 3.7 2.7 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sec8_exocyst PF04048.14 GBG80736.1 - 0.054 13.4 0.4 0.054 13.4 0.4 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF16 PF01519.16 GBG80736.1 - 0.079 13.5 10.6 0.22 12.0 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 YabA PF06156.13 GBG80736.1 - 0.083 13.5 1.0 0.083 13.5 1.0 2.6 2 0 0 2 2 2 0 Initiation control protein YabA BRE1 PF08647.11 GBG80736.1 - 0.37 10.9 14.7 0.2 11.8 3.8 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase PEARLI-4 PF05278.12 GBG80736.1 - 1.4 8.4 14.1 2.2 7.8 3.0 2.3 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) USP8_interact PF08941.10 GBG80736.1 - 2.4 7.9 7.5 0.12 12.1 0.4 2.1 2 0 0 2 2 2 0 USP8 interacting Rx_N PF18052.1 GBG80736.1 - 3.7 7.9 10.2 0.15 12.4 3.8 2.0 2 0 0 2 2 2 0 Rx N-terminal domain Pkinase PF00069.25 GBG80737.1 - 7.9e-56 189.3 0.0 7.9e-56 189.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG80737.1 - 5.2e-27 94.8 0.0 1e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF659 PF04937.15 GBG80737.1 - 1.9e-15 57.0 0.0 4.2e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Mad3_BUB1_I PF08311.12 GBG80737.1 - 2.5e-11 43.6 0.1 6.6e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 GBG80737.1 - 0.00058 20.0 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Pkinase_fungal PF17667.1 GBG80737.1 - 0.0038 16.0 0.0 0.0038 16.0 0.0 3.3 2 1 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 GBG80737.1 - 0.0057 16.3 0.0 0.0057 16.3 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Prominin PF05478.11 GBG80739.1 - 0.0018 16.3 2.1 0.003 15.6 2.1 1.3 1 0 0 1 1 1 1 Prominin CENP-F_leu_zip PF10473.9 GBG80739.1 - 0.11 12.5 29.3 0.18 11.8 0.0 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 GBG80739.1 - 1.2 8.4 21.6 0.013 14.9 10.5 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 GBG80739.1 - 1.5 9.0 26.6 0.037 14.2 12.7 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Occludin_ELL PF07303.13 GBG80739.1 - 7.3 7.4 10.7 3.2 8.6 1.9 2.7 2 0 0 2 2 2 0 Occludin homology domain TilS PF09179.11 GBG80740.1 - 0.012 16.1 0.6 0.19 12.3 0.3 2.6 1 1 1 2 2 2 0 TilS substrate binding domain PRIMA1 PF16101.5 GBG80740.1 - 8.5 6.4 15.1 14 5.7 11.9 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Lycopene_cycl PF05834.12 GBG80741.1 - 3e-93 312.9 0.1 1.3e-88 297.7 0.0 2.2 1 1 1 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GBG80741.1 - 4.4e-07 29.4 1.0 0.00062 19.1 0.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG80741.1 - 0.00024 20.0 0.9 0.037 12.7 0.6 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 GBG80741.1 - 0.017 14.2 1.4 0.033 13.3 1.4 1.4 1 0 0 1 1 1 0 FAD binding domain SR-25 PF10500.9 GBG80741.1 - 0.02 14.5 6.8 0.038 13.6 6.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DAO PF01266.24 GBG80741.1 - 0.026 14.1 3.7 1.7 8.2 0.0 2.4 1 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 GBG80741.1 - 0.038 13.1 0.1 0.091 11.8 0.1 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 GBG80741.1 - 0.082 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 GBG80741.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Keratin_2_head PF16208.5 GBG80741.1 - 0.24 11.5 17.5 0.24 11.5 6.9 2.7 2 0 0 2 2 2 0 Keratin type II head IMUP PF15761.5 GBG80741.1 - 6.1 7.6 10.1 0.59 10.9 4.7 2.0 2 0 0 2 2 2 0 Immortalisation up-regulated protein FAD_oxidored PF12831.7 GBG80741.1 - 8.1 5.7 10.4 0.19 11.0 1.9 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase RVT_1 PF00078.27 GBG80742.1 - 1.6e-34 119.4 0.0 2.5e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NDUF_B12 PF08122.12 GBG80744.1 - 0.69 10.0 4.5 10 6.3 0.1 2.5 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family FoP_duplication PF13865.6 GBG80744.1 - 2.6 8.7 23.1 5.9 7.5 10.9 2.5 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 RVT_1 PF00078.27 GBG80745.1 - 8.1e-25 87.6 0.0 1.7e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80745.1 - 7.8e-18 64.3 1.2 3.3e-17 62.3 0.8 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG80745.1 - 6.7e-13 48.8 0.1 3.3e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80745.1 - 1.1e-09 38.2 0.0 3.2e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80745.1 - 4.3e-09 36.6 0.3 1.3e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG80745.1 - 5.4e-07 30.2 0.0 1.8e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80745.1 - 5.5e-07 30.1 0.0 1.7e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80745.1 - 0.00053 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80745.1 - 0.00071 19.4 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG80745.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG80747.1 - 1.9e-12 47.1 0.0 4.2e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80747.1 - 2.4e-06 27.3 0.0 5.4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein T3SSipB PF16535.5 GBG80747.1 - 0.027 15.0 3.6 0.045 14.2 3.6 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB KELK PF15796.5 GBG80747.1 - 0.1 13.1 2.2 0.23 12.0 2.2 1.5 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GAS PF13851.6 GBG80747.1 - 0.11 11.8 0.1 0.36 10.2 0.1 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CorA PF01544.18 GBG80747.1 - 0.35 10.1 1.6 1.2 8.4 1.9 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DHR10 PF18595.1 GBG80747.1 - 0.49 10.5 10.3 3.6 7.7 1.1 3.3 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Golgin_A5 PF09787.9 GBG80747.1 - 2.4 7.5 6.2 9.3 5.6 6.2 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 APG6_N PF17675.1 GBG80747.1 - 5.8 7.5 7.9 0.82 10.2 2.0 2.3 3 0 0 3 3 3 0 Apg6 coiled-coil region RT_RNaseH_2 PF17919.1 GBG80748.1 - 1.8e-31 108.1 0.0 3.1e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80748.1 - 2e-27 96.1 0.3 3.8e-27 95.3 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80748.1 - 1e-26 93.2 0.0 2.2e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG80749.1 - 1e-09 38.6 4.7 1e-09 38.6 4.7 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG80749.1 - 0.061 13.5 1.1 0.16 12.2 0.1 2.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain Cellulose_synt PF03552.14 GBG80750.1 - 0 1153.9 1.0 0 1153.4 1.0 1.2 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.6 GBG80750.1 - 1.2e-17 63.8 6.6 1.2e-17 63.8 6.6 2.0 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 GBG80750.1 - 3e-12 46.1 12.7 3e-12 46.1 12.7 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Glyco_trans_2_3 PF13632.6 GBG80750.1 - 2.1e-06 27.8 2.1 2.1e-06 27.8 2.1 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG80750.1 - 5.6e-06 26.3 0.1 0.00022 21.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG80750.1 - 0.034 14.0 0.1 4 7.3 0.0 3.0 3 0 0 3 3 3 0 Glycosyltransferase like family 2 DUF2090 PF09863.9 GBG80751.1 - 0.043 12.9 0.1 0.066 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Cellulose_synt PF03552.14 GBG80752.1 - 2e-143 479.5 10.8 5.2e-81 273.2 0.2 2.2 1 1 1 2 2 2 2 Cellulose synthase zf-UDP PF14569.6 GBG80752.1 - 7.1e-20 70.9 6.3 1.3e-19 70.0 6.3 1.3 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 GBG80752.1 - 2.2e-12 46.5 12.4 3.9e-12 45.8 12.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 GBG80752.1 - 0.12 12.3 6.4 0.33 10.8 6.4 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GBG80752.1 - 0.19 12.1 9.5 0.37 11.2 9.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 GBG80752.1 - 0.3 11.0 7.2 0.51 10.3 7.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 GBG80752.1 - 0.9 9.8 3.0 1.8 8.8 3.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_5 PF14634.6 GBG80752.1 - 2.4 8.2 9.9 4.4 7.3 9.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Cellulose_synt PF03552.14 GBG80753.1 - 0 1146.0 4.7 0 1145.2 4.7 1.3 1 1 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.6 GBG80753.1 - 2e-19 69.5 6.6 2e-19 69.5 6.6 1.9 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 GBG80753.1 - 1.7e-12 46.9 12.9 1.7e-12 46.9 12.9 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Glyco_trans_2_3 PF13632.6 GBG80753.1 - 1.9e-07 31.2 8.9 1.9e-06 27.9 1.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG80753.1 - 8.6e-05 22.4 0.1 0.00024 20.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 CYSTM PF12734.7 GBG80753.1 - 0.029 14.7 10.7 0.12 12.7 10.7 2.1 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Glyco_tranf_2_3 PF13641.6 GBG80753.1 - 0.13 12.1 0.1 0.82 9.5 0.0 2.2 3 0 0 3 3 3 0 Glycosyltransferase like family 2 RT_RNaseH_2 PF17919.1 GBG80754.1 - 9.2e-31 105.9 0.0 1.9e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80754.1 - 8.1e-26 90.4 0.2 1.8e-25 89.2 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80754.1 - 3.3e-10 39.9 0.0 8.4e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG80754.1 - 0.016 15.1 0.3 0.032 14.2 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Mcp5_PH PF12814.7 GBG80754.1 - 0.1 12.7 0.4 0.25 11.5 0.4 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology zf-CCHC PF00098.23 GBG80754.1 - 2.6 8.3 4.3 4.5 7.5 4.3 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG80755.1 - 5.2e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80757.1 - 1.5e-22 79.5 0.0 5.8e-16 58.4 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80757.1 - 9.7e-17 61.2 0.0 2.1e-14 53.6 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80757.1 - 3.5e-10 40.1 0.0 1.1e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80759.1 - 1.4e-102 336.3 0.0 2.5e-34 117.3 0.0 4.8 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80759.1 - 1.3e-87 288.9 0.0 3.1e-30 104.5 0.1 4.8 4 0 0 4 4 4 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80759.1 - 1.7e-46 158.6 0.3 9.9e-25 87.3 0.0 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80759.1 - 3.2e-20 72.5 0.0 1.2e-11 44.9 0.0 3.0 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG80759.1 - 1.1e-15 57.5 1.7 2e-15 56.7 0.5 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG80759.1 - 5.5e-09 36.2 0.4 0.039 14.2 0.0 5.1 4 0 0 4 4 4 2 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG80760.1 - 2.3e-37 127.0 0.0 4.7e-26 90.7 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80760.1 - 2.7e-27 95.1 0.0 1.3e-24 86.5 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80760.1 - 2.2e-25 89.5 0.0 4.4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80760.1 - 2.7e-16 59.4 0.5 9.3e-16 57.7 0.5 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80760.1 - 3.4e-06 27.2 0.0 1.3e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG80760.1 - 0.0029 17.8 3.1 0.025 14.8 0.1 3.7 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG80760.1 - 0.2 12.3 0.0 0.55 10.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease TSA PF03249.13 GBG80760.1 - 4.4 6.0 5.4 7.5 5.2 5.4 1.3 1 0 0 1 1 1 0 Type specific antigen RT_RNaseH_2 PF17919.1 GBG80762.1 - 3.3e-26 91.2 0.0 1.8e-25 88.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80762.1 - 1.3e-22 80.5 0.0 2.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80762.1 - 3.2e-16 59.5 0.0 2.1e-15 56.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG80762.1 - 3.3e-07 30.8 0.0 9e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80762.1 - 7.1e-07 29.8 0.0 1.7e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG80762.1 - 5.9e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80762.1 - 0.0037 17.1 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG80762.1 - 0.0059 16.8 0.0 0.0059 16.8 0.0 4.2 5 0 0 5 5 4 1 Retrotransposon gag protein OSCP PF00213.18 GBG80762.1 - 0.042 14.0 1.6 0.23 11.6 0.2 2.4 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit YabA PF06156.13 GBG80762.1 - 0.16 12.6 1.6 2.7 8.7 0.0 3.2 3 0 0 3 3 3 0 Initiation control protein YabA Phage_GPO PF05929.11 GBG80762.1 - 9.7 5.7 6.8 11 5.6 0.4 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Succ_DH_flav_C PF02910.20 GBG80763.1 - 0.00068 19.6 3.8 0.21 11.6 0.3 2.9 1 1 0 2 2 2 2 Fumarate reductase flavoprotein C-term SIN1 PF05422.12 GBG80763.1 - 0.28 11.8 10.7 1.6 9.2 0.2 3.7 2 1 1 3 3 3 0 Stress-activated map kinase interacting protein 1 (SIN1) MSA-2c PF12238.8 GBG80763.1 - 4.3 7.3 9.4 9.8 6.1 9.4 1.5 1 1 0 1 1 1 0 Merozoite surface antigen 2c RVT_1 PF00078.27 GBG80764.1 - 3.3e-21 75.8 0.0 5.4e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80764.1 - 2.3e-06 27.4 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80764.1 - 5.6e-06 26.9 0.0 1.3e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG80764.1 - 5.1e-05 23.4 0.0 0.00017 21.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG80764.1 - 0.0015 19.1 0.0 0.0029 18.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80764.1 - 0.037 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG80765.1 - 8e-32 110.5 0.1 1.3e-31 109.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80765.1 - 8.9e-17 61.0 0.1 2.6e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80765.1 - 5.4e-05 23.4 0.4 0.00022 21.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HALZ PF02183.18 GBG80765.1 - 0.023 14.9 1.2 0.073 13.3 1.2 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper EMP24_GP25L PF01105.24 GBG80765.1 - 0.19 11.6 8.8 0.37 10.7 0.2 3.9 4 0 0 4 4 4 0 emp24/gp25L/p24 family/GOLD TSC22 PF01166.18 GBG80765.1 - 0.55 10.6 3.4 3.7 7.9 1.5 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family FlaC_arch PF05377.11 GBG80765.1 - 3.6 8.0 5.9 2.1 8.8 0.9 3.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Herpes_capsid PF06112.11 GBG80765.1 - 8.8 6.4 10.8 0.33 11.0 3.8 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Yae1_N PF09811.9 GBG80769.1 - 0.00028 20.5 2.2 0.05 13.3 0.7 2.6 2 0 0 2 2 2 2 Essential protein Yae1, N terminal ADIP PF11559.8 GBG80769.1 - 0.064 13.3 0.2 0.097 12.8 0.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ECR1_N PF14382.6 GBG80770.1 - 1.3e-06 28.1 0.2 3e-06 26.9 0.2 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 GBG80770.1 - 0.0032 18.0 0.0 0.0069 17.0 0.0 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 DUF659 PF04937.15 GBG80771.1 - 4.2e-32 111.1 0.0 9.9e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf_C2H2_6 PF18450.1 GBG80771.1 - 0.077 12.7 0.3 0.21 11.3 0.3 1.7 1 0 0 1 1 1 0 Zinc Finger domain DUF1564 PF07600.11 GBG80772.1 - 0.041 13.6 0.0 0.27 10.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) KH_6 PF15985.5 GBG80774.1 - 1.2e-13 51.2 0.0 2.5e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 KH domain gag-asp_proteas PF13975.6 GBG80775.1 - 5.2e-05 23.7 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80775.1 - 0.00026 21.6 0.0 0.00052 20.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80775.1 - 0.0071 16.1 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Peripla_BP_2 PF01497.18 GBG80776.1 - 3.6e-08 33.3 0.1 8.7e-08 32.0 0.1 1.7 1 1 0 1 1 1 1 Periplasmic binding protein RVT_1 PF00078.27 GBG80776.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4482 PF14818.6 GBG80777.1 - 0.0081 17.0 2.1 0.0081 17.0 2.1 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4482) KIAA1430 PF13879.6 GBG80777.1 - 0.029 15.1 1.1 0.063 14.0 0.7 1.8 1 1 0 1 1 1 0 KIAA1430 homologue MerR-DNA-bind PF09278.11 GBG80777.1 - 0.087 13.4 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 MerR, DNA binding TPR_MLP1_2 PF07926.12 GBG80777.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SAGA-Tad1 PF12767.7 GBG80777.1 - 0.89 9.2 6.4 1.8 8.2 6.2 1.6 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Taxilin PF09728.9 GBG80777.1 - 1.4 8.0 7.6 0.055 12.7 2.0 1.6 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Borrelia_P83 PF05262.11 GBG80777.1 - 5.2 5.4 13.3 10 4.5 13.3 1.6 1 1 0 1 1 1 0 Borrelia P83/100 protein RVT_1 PF00078.27 GBG80778.1 - 4e-22 78.8 0.2 4.6e-21 75.4 0.0 2.4 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80778.1 - 2.9e-16 59.3 0.0 9.5e-16 57.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80778.1 - 3.9e-08 33.5 0.0 3.2e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80778.1 - 0.00059 20.1 4.3 0.0025 18.1 0.1 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein BLOC1_2 PF10046.9 GBG80778.1 - 0.026 14.8 6.2 0.088 13.1 2.8 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2681 PF10883.8 GBG80778.1 - 0.14 12.5 2.7 0.58 10.6 2.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) SPACA9 PF15120.6 GBG80778.1 - 0.19 11.5 2.1 0.48 10.2 1.3 2.1 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 SYCE1 PF15233.6 GBG80778.1 - 0.51 10.4 13.0 2.5 8.1 0.1 2.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 DivIC PF04977.15 GBG80778.1 - 0.89 9.4 5.6 0.36 10.6 1.8 2.4 2 0 0 2 2 2 0 Septum formation initiator LPP PF04728.13 GBG80778.1 - 4.4 7.8 6.4 18 5.8 0.1 3.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper SlyX PF04102.12 GBG80778.1 - 5.1 7.8 10.6 1.3 9.7 3.0 3.3 3 0 0 3 3 2 0 SlyX NPV_P10 PF05531.12 GBG80778.1 - 9.3 6.8 6.9 32 5.1 2.2 2.8 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CDC27 PF09507.10 GBG80779.1 - 0.003 17.0 22.4 0.0037 16.7 22.4 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF4566 PF15130.6 GBG80779.1 - 0.13 11.7 0.1 0.31 10.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4566) ALMT PF11744.8 GBG80779.1 - 0.3 9.9 4.9 0.44 9.3 4.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SDA1 PF05285.12 GBG80779.1 - 5.1 6.4 59.2 12 5.2 59.2 1.5 1 0 0 1 1 1 0 SDA1 AAA_11 PF13086.6 GBG80779.1 - 6.5 6.5 9.7 13 5.5 9.7 1.5 1 0 0 1 1 1 0 AAA domain BLM_N PF16202.5 GBG80780.1 - 0.21 10.7 8.2 0.34 10.0 8.2 1.3 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein Pox_A_type_inc PF04508.12 GBG80780.1 - 0.22 11.4 0.1 0.22 11.4 0.1 2.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Fzo_mitofusin PF04799.13 GBG80780.1 - 4.6 6.8 7.8 0.76 9.3 1.9 2.1 2 0 0 2 2 2 0 fzo-like conserved region Chromo PF00385.24 GBG80781.1 - 9.7e-05 22.2 0.3 0.00025 20.9 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG80781.1 - 0.0037 16.8 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80781.1 - 0.004 17.3 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG80781.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG80781.1 - 0.041 14.2 0.3 0.041 14.2 0.3 2.8 4 0 0 4 4 4 0 Retrotransposon gag protein N6_N4_Mtase PF01555.18 GBG80782.1 - 1.5e-06 28.1 0.0 1.9e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 DNA methylase Asp_protease_2 PF13650.6 GBG80783.1 - 0.00041 20.9 0.0 0.0012 19.4 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80783.1 - 0.0024 18.4 0.0 0.005 17.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Apolipoprotein PF01442.18 GBG80783.1 - 0.071 13.0 4.5 0.13 12.1 4.5 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Asp_protease_2 PF13650.6 GBG80785.1 - 0.0084 16.7 0.0 0.029 15.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80785.1 - 0.018 15.6 0.0 0.045 14.3 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG80785.1 - 0.094 12.8 3.1 0.2 11.8 3.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG80790.1 - 1.3e-32 111.8 0.0 4.7e-32 110.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80790.1 - 6.9e-20 71.3 0.0 1.5e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80790.1 - 8.5e-11 41.8 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80790.1 - 0.0095 16.1 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Nop14 PF04147.12 GBG80791.1 - 0.015 13.5 11.5 0.019 13.2 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 GBG80791.1 - 0.031 13.4 31.1 0.049 12.8 31.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 GBG80791.1 - 0.24 10.7 12.3 0.32 10.3 12.3 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG80791.1 - 0.6 9.5 18.5 1.3 8.4 18.5 1.5 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 GBG80791.1 - 1.4 9.0 17.9 0.13 12.3 12.8 1.8 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 GBG80791.1 - 4.1 5.6 16.0 6.3 5.0 16.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.13 GBG80791.1 - 5.6 5.4 13.9 11 4.4 13.9 1.4 1 0 0 1 1 1 0 Utp14 protein zf-CCHC PF00098.23 GBG80792.1 - 5.5e-05 23.1 3.7 8.6e-05 22.4 3.7 1.3 1 0 0 1 1 1 1 Zinc knuckle PV-1 PF06637.11 GBG80792.1 - 0.023 13.5 12.3 0.033 13.0 12.3 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) zf-CCHC_2 PF13696.6 GBG80792.1 - 0.034 14.0 1.7 0.055 13.3 1.7 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4456 PF14644.6 GBG80792.1 - 0.15 11.7 10.8 0.065 12.9 7.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) PBP_sp32 PF07222.12 GBG80792.1 - 1.5 8.2 13.7 0.2 11.1 8.9 1.8 2 1 1 3 3 3 0 Proacrosin binding protein sp32 GST_C_5 PF16865.5 GBG80795.1 - 5.4e-09 36.6 0.0 1.8e-07 31.7 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GBG80795.1 - 2e-08 34.1 0.1 1.1e-07 31.7 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Hemerythrin PF01814.23 GBG80795.1 - 3.4e-07 30.9 12.1 7.8e-07 29.8 4.9 3.4 2 1 1 3 3 3 2 Hemerythrin HHE cation binding domain GST_C PF00043.25 GBG80795.1 - 0.0012 19.0 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GBG80795.1 - 0.018 15.4 2.7 3.2 8.2 0.0 3.7 5 1 1 6 6 6 0 Glutathione S-transferase, N-terminal domain Mfp-3 PF04202.13 GBG80795.1 - 3.8 8.0 4.9 0.85 10.1 1.3 1.8 2 0 0 2 2 2 0 Foot protein 3 DUF659 PF04937.15 GBG80797.1 - 1.8e-22 79.8 0.0 2.8e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) UPF0561 PF10573.9 GBG80797.1 - 0.064 13.4 0.3 0.21 11.7 0.3 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 DUF3100 PF11299.8 GBG80797.1 - 2.7 7.3 4.2 4.9 6.5 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) rve PF00665.26 GBG80798.1 - 0.00029 21.0 0.0 0.0021 18.2 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain RT_RNaseH PF17917.1 GBG80799.1 - 8.8e-08 32.4 0.2 2.5e-07 30.9 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80799.1 - 2.6e-05 24.2 0.1 0.00026 21.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80800.1 - 2.9e-16 59.3 0.0 8.9e-16 57.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80800.1 - 1.2e-05 25.6 0.0 2.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80800.1 - 0.00022 20.8 0.1 0.00037 20.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG80801.1 - 1.8e-34 119.2 0.1 2.9e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80801.1 - 1e-17 64.0 0.0 2.9e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80801.1 - 1.7e-16 60.5 0.0 3.4e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG80801.1 - 2.6e-05 24.4 0.0 9.6e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase CCDC85 PF10226.9 GBG80801.1 - 0.036 13.7 0.2 0.088 12.5 0.2 1.6 1 0 0 1 1 1 0 CCDC85 family DUF2385 PF09539.10 GBG80801.1 - 0.056 14.0 0.1 0.96 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) rve_3 PF13683.6 GBG80801.1 - 0.11 12.3 0.0 0.44 10.4 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain Integrase_H2C2 PF17921.1 GBG80801.1 - 0.16 12.1 0.6 2.1 8.5 0.5 2.5 2 0 0 2 2 2 0 Integrase zinc binding domain XhlA PF10779.9 GBG80801.1 - 0.44 10.8 1.7 0.96 9.7 0.2 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Rad52_Rad22 PF04098.15 GBG80802.1 - 0.019 14.9 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein Ribosomal_S30AE PF02482.19 GBG80802.1 - 0.055 14.3 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein RVT_1 PF00078.27 GBG80803.1 - 3.2e-17 62.8 0.2 6.2e-17 61.9 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIN_4 PF13638.6 GBG80803.1 - 6.2 7.1 5.8 15 5.9 5.8 1.6 1 0 0 1 1 1 0 PIN domain RT_RNaseH_2 PF17919.1 GBG80804.1 - 7.3e-32 109.4 0.1 1.5e-31 108.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80804.1 - 3.6e-30 104.3 0.2 8.3e-30 103.2 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80804.1 - 3.1e-20 72.6 0.0 5.9e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80806.1 - 3e-13 50.0 0.0 7.4e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG80806.1 - 1.2e-11 44.5 0.0 3.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80806.1 - 1.6e-10 41.2 0.0 3.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG80806.1 - 5.7e-05 23.6 0.0 0.00015 22.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80806.1 - 0.013 16.1 0.0 0.028 15.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG80806.1 - 0.047 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG80806.1 - 0.097 12.4 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG80806.1 - 0.55 10.4 10.9 0.016 15.3 3.4 2.2 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG80807.1 - 1.6e-27 95.5 0.0 2.2e-26 91.8 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80807.1 - 3.6e-24 85.1 0.1 8.2e-24 83.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80807.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Caldesmon PF02029.15 GBG80807.1 - 0.034 12.9 61.3 0.047 12.5 61.3 1.2 1 0 0 1 1 1 0 Caldesmon Nop14 PF04147.12 GBG80807.1 - 0.36 9.0 70.7 0.6 8.3 70.7 1.3 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG80808.1 - 0.027 13.3 4.2 0.028 13.2 4.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG80808.1 - 0.12 10.5 30.9 0.14 10.3 30.9 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG80808.1 - 0.16 11.4 30.4 0.19 11.1 30.4 1.0 1 0 0 1 1 1 0 SDA1 CCSAP PF15748.5 GBG80808.1 - 0.24 11.5 8.9 0.29 11.3 8.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 GBG80808.1 - 1.2 7.3 25.5 1.5 7.1 25.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.6 GBG80808.1 - 8.8 5.8 10.8 10 5.6 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF4484 PF14831.6 GBG80808.1 - 9.5 6.2 15.0 13 5.8 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Integrase_H2C2 PF17921.1 GBG80809.1 - 1.1e-13 51.0 0.3 1.1e-13 51.0 0.3 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG80809.1 - 5.7e-13 49.1 0.0 1.4e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG80809.1 - 9.1e-09 35.1 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG80809.1 - 5e-06 27.0 0.1 6e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG80809.1 - 5.3e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80809.1 - 0.00077 19.7 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG80809.1 - 0.0045 17.6 0.1 0.016 15.8 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.10 GBG80809.1 - 0.029 14.6 0.8 0.082 13.1 0.8 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG80810.1 - 1.9e-24 86.4 0.1 3.6e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG80810.1 - 1e-09 38.6 0.0 2.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG80810.1 - 5.7e-05 23.6 0.0 0.00015 22.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80810.1 - 0.0071 16.1 0.0 0.027 14.2 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80810.1 - 0.041 14.5 0.0 0.13 13.0 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_3 PF13917.6 GBG80810.1 - 0.1 12.6 7.6 0.022 14.7 1.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG80810.1 - 0.12 12.5 14.3 0.12 12.4 2.7 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG80810.1 - 0.81 9.5 8.3 1.5 8.6 1.1 2.7 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG80811.1 - 2.5e-59 197.5 0.0 3.7e-30 103.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80811.1 - 9e-56 188.9 0.0 4.6e-30 104.8 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80811.1 - 1.2e-52 176.6 0.0 4.7e-26 91.1 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80811.1 - 0.0054 17.0 0.0 0.058 13.7 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein RNR_Alpha PF17975.1 GBG80812.1 - 0.021 15.3 0.8 0.095 13.2 0.0 2.2 2 1 0 2 2 2 0 Ribonucleotide reductase alpha domain DUF3006 PF11213.8 GBG80812.1 - 0.31 11.3 2.1 0.62 10.3 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) AIF-MLS PF14962.6 GBG80812.1 - 0.38 10.7 4.3 1 9.3 2.9 2.0 2 0 0 2 2 2 0 Mitochondria Localisation Sequence DUF4407 PF14362.6 GBG80812.1 - 0.39 10.0 15.1 0.37 10.1 6.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG80813.1 - 2.6e-28 99.1 0.1 4e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG80813.1 - 5.5e-06 26.9 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80813.1 - 0.00015 22.3 0.0 0.00046 20.8 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG80813.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80813.1 - 0.0038 17.0 0.2 0.01 15.7 0.2 1.7 1 1 0 1 1 1 1 Aspartyl protease DUF2862 PF11061.8 GBG80813.1 - 0.006 16.4 0.3 0.026 14.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2862) DUF1758 PF05585.12 GBG80813.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF5095 PF17016.5 GBG80813.1 - 0.063 13.0 0.3 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) rve PF00665.26 GBG80814.1 - 3.2e-15 56.4 0.0 5.8e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG80814.1 - 5e-12 45.7 0.0 1.4e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG80814.1 - 0.0042 16.8 0.0 0.013 15.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG80814.1 - 0.019 15.5 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Toprim_N PF08275.11 GBG80815.1 - 5.2e-05 23.3 5.7 33 4.5 0.0 6.7 2 2 4 6 6 6 0 DNA primase catalytic core, N-terminal domain SH3_19 PF18597.1 GBG80815.1 - 6.6e-05 22.7 31.8 17 5.3 0.1 9.2 9 0 0 9 9 9 2 Myosin X N-terminal SH3 domain PapC_C PF13953.6 GBG80815.1 - 0.00012 21.8 29.4 2 8.3 0.1 7.8 1 1 9 10 10 10 5 PapC C-terminal domain RTA1 PF04479.13 GBG80815.1 - 0.00053 19.7 12.2 15 5.1 0.0 6.9 2 2 6 8 8 8 1 RTA1 like protein DCR PF14047.6 GBG80815.1 - 0.016 15.4 7.0 39 4.6 0.1 5.9 2 2 5 7 7 7 0 Dppa2/4 conserved region FBA_3 PF08268.12 GBG80815.1 - 0.46 10.4 14.5 7.9 6.4 0.3 4.6 1 1 4 6 6 6 0 F-box associated domain ImpE PF07024.13 GBG80815.1 - 0.55 10.3 15.8 32 4.6 0.3 5.9 2 2 5 7 7 7 0 ImpE protein DdrB PF12747.7 GBG80815.1 - 2.4 8.0 17.4 17 5.3 1.7 4.9 1 1 2 4 4 4 0 DdrB-like protein DUF2917 PF11142.8 GBG80815.1 - 5 6.6 32.8 2.4 7.6 0.5 7.1 3 2 6 9 9 9 0 Protein of unknown function (DUF2917) ATP_transf PF09830.9 GBG80815.1 - 9.9 6.4 13.8 71 3.7 0.1 6.1 1 1 6 7 7 7 0 ATP adenylyltransferase RVT_1 PF00078.27 GBG80816.1 - 0.0022 17.5 0.0 0.0072 15.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG80816.1 - 0.0083 16.4 0.2 0.056 13.7 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein Diphthami_syn_2 PF01902.17 GBG80816.1 - 0.032 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Diphthamide synthase Filamin PF00630.19 GBG80817.1 - 6.1e-81 267.9 0.0 2.8e-09 37.7 0.0 19.8 20 0 0 20 20 20 13 Filamin/ABP280 repeat Cadherin-like PF12733.7 GBG80817.1 - 7.8e-11 42.4 19.1 3.6e-06 27.4 0.2 8.5 10 0 0 10 10 10 3 Cadherin-like beta sandwich domain Invasin_D3 PF09134.10 GBG80817.1 - 1.7e-09 37.8 34.2 1.7 9.0 0.0 13.8 15 0 0 15 15 15 5 Invasin, domain 3 Big_1 PF02369.16 GBG80817.1 - 0.013 15.5 29.5 1.6 8.8 0.0 11.0 12 0 0 12 12 12 0 Bacterial Ig-like domain (group 1) Filamin PF00630.19 GBG80819.1 - 7.3e-47 158.4 0.0 1.6e-10 41.7 0.0 9.2 9 0 0 9 9 9 5 Filamin/ABP280 repeat REJ PF02010.15 GBG80819.1 - 1.8e-13 50.2 0.0 2.7e-05 23.2 0.0 3.3 3 0 0 3 3 3 3 REJ domain Invasin_D3 PF09134.10 GBG80819.1 - 2.3e-08 34.2 16.5 0.055 13.8 0.1 6.8 6 1 1 7 7 7 4 Invasin, domain 3 Dimer_Tnp_hAT PF05699.14 GBG80819.1 - 2.2e-06 27.4 0.1 5.3e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG80819.1 - 0.00091 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) YtkA PF13115.6 GBG80819.1 - 0.066 13.8 0.2 1.5 9.5 0.0 3.4 2 0 0 2 2 2 0 YtkA-like SUIM_assoc PF16619.5 GBG80819.1 - 0.16 12.1 4.0 0.41 10.8 4.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Big_1 PF02369.16 GBG80819.1 - 0.86 9.7 8.7 5.5 7.1 0.0 5.0 4 1 0 4 4 4 0 Bacterial Ig-like domain (group 1) SKG6 PF08693.10 GBG80819.1 - 8.1 5.9 8.3 0.54 9.7 2.2 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain RT_RNaseH PF17917.1 GBG80820.1 - 2.5e-07 31.0 0.1 5e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80820.1 - 6.5e-05 22.9 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FtsK_SpoIIIE PF01580.18 GBG80820.1 - 0.12 11.7 0.3 0.25 10.7 0.3 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DDE_Tnp_4 PF13359.6 GBG80823.1 - 6.7e-11 42.1 0.0 2e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80823.1 - 5.9e-06 26.0 0.0 9.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein RT_RNaseH_2 PF17919.1 GBG80824.1 - 3.1e-24 84.9 0.0 8.1e-24 83.6 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80824.1 - 2.3e-20 72.9 0.0 1.8e-19 69.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80824.1 - 1.1e-13 51.4 0.0 2.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG80824.1 - 1.3e-13 50.8 0.1 3.4e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG80824.1 - 0.0054 16.5 0.0 0.019 14.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80824.1 - 0.18 12.1 0.1 0.42 10.9 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger SNF2_N PF00176.23 GBG80826.1 - 1.1e-82 277.6 0.0 1.5e-82 277.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG80826.1 - 2.2e-16 60.2 0.0 4.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 GBG80826.1 - 8.9e-12 44.8 0.0 2.3e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_3 PF13920.6 GBG80826.1 - 5.3e-10 39.0 8.3 5.3e-10 39.0 8.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG80826.1 - 4.2e-08 32.9 8.9 1.4e-07 31.3 8.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG80826.1 - 6.2e-08 32.4 7.8 1.5e-07 31.2 7.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GBG80826.1 - 8.1e-08 32.0 7.5 8.1e-08 32.0 7.5 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG80826.1 - 1.2e-07 31.9 9.4 3.5e-07 30.5 9.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG80826.1 - 1.5e-07 31.3 9.5 1.2e-06 28.4 3.2 3.8 3 0 0 3 3 3 1 RING-type zinc-finger DEAD PF00270.29 GBG80826.1 - 4.1e-06 26.7 0.0 8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 GBG80826.1 - 4.8e-05 23.2 7.4 0.00014 21.7 7.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 GBG80826.1 - 0.00042 20.3 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 GBG80826.1 - 0.0074 16.4 9.3 0.0074 16.4 9.3 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GBG80826.1 - 0.16 11.9 3.2 0.57 10.1 3.2 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 GBG80826.1 - 0.2 11.7 3.7 0.52 10.4 3.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GBG80826.1 - 5.2 6.9 13.1 0.63 9.9 8.1 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF659 PF04937.15 GBG80827.1 - 9.4e-08 32.1 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) cwf21 PF08312.12 GBG80827.1 - 0.087 13.0 0.0 21 5.4 0.0 3.4 3 1 0 3 3 3 0 cwf21 domain Cwf_Cwc_15 PF04889.12 GBG80827.1 - 0.82 9.4 7.8 0.092 12.5 2.6 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 GBG80827.1 - 2.2 8.3 8.3 0.22 11.6 3.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein U3_assoc_6 PF08640.11 GBG80828.1 - 1.4e-24 85.9 4.1 5e-23 81.0 2.7 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 GBG80828.1 - 7.8e-05 23.2 12.4 0.053 14.4 0.3 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat NRDE-2 PF08424.10 GBG80828.1 - 0.0044 16.2 4.5 0.093 11.8 0.6 3.6 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference CDC45 PF02724.14 GBG80828.1 - 0.53 8.5 4.2 0.78 8.0 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG80828.1 - 3.9 6.8 15.3 0.25 10.7 9.7 1.8 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 GBG80828.1 - 5.1 5.2 16.0 7.8 4.6 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG80828.1 - 5.5 5.0 12.5 8.9 4.3 12.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi RVT_1 PF00078.27 GBG80829.1 - 6.4e-29 101.0 0.1 1.1e-28 100.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80829.1 - 2.5e-08 34.4 0.0 6.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80829.1 - 4.6e-08 33.5 0.0 1.1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80829.1 - 3.4e-06 26.9 0.0 7.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG80829.1 - 9.3e-06 25.4 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease CHCH PF06747.13 GBG80830.1 - 8.5e-09 35.3 10.9 2.5e-07 30.6 3.7 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 GBG80830.1 - 6.5e-07 29.3 8.6 0.0011 18.9 1.4 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 GBG80830.1 - 0.027 14.5 9.9 0.069 13.2 0.8 2.3 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 GBG80830.1 - 1.3 9.3 11.9 0.1 12.9 3.3 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 GBG80830.1 - 2.2 8.6 8.9 5.8 7.3 1.2 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 RVT_1 PF00078.27 GBG80831.1 - 6.4e-38 130.5 0.1 9.2e-38 130.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Collagen PF01391.18 GBG80831.1 - 5.8 6.8 9.4 1.7 8.4 3.7 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) RT_RNaseH_2 PF17919.1 GBG80833.1 - 2.7e-26 91.5 0.0 9.1e-26 89.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80833.1 - 2.1e-24 85.8 0.0 5.5e-24 84.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80833.1 - 3e-20 72.7 0.0 6e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF572 PF04502.13 GBG80833.1 - 0.079 12.6 4.7 0.14 11.7 4.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) BLOC1_2 PF10046.9 GBG80833.1 - 0.12 12.7 6.8 0.18 12.1 5.3 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HIP1_clath_bdg PF16515.5 GBG80833.1 - 0.15 12.7 25.5 0.03 14.9 16.8 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MAD PF05557.13 GBG80833.1 - 1.5 7.1 21.7 2.4 6.4 21.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein VIT1 PF01988.19 GBG80833.1 - 6.4 6.6 9.2 0.78 9.6 3.6 2.0 1 1 1 2 2 2 0 VIT family RT_RNaseH_2 PF17919.1 GBG80834.1 - 4.5e-34 116.5 0.0 1.1e-33 115.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80834.1 - 1.7e-27 95.7 0.0 5.3e-27 94.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80834.1 - 5.5e-10 39.2 0.1 1.2e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG80834.1 - 0.082 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Med26_C PF15693.5 GBG80836.1 - 0.86 9.7 9.2 15 5.7 8.5 2.3 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal CDC27 PF09507.10 GBG80836.1 - 1.3 8.3 21.0 2.4 7.4 21.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ACC_epsilon PF13822.6 GBG80836.1 - 3.3 8.5 0.0 3.3 8.5 0.0 3.5 4 0 0 4 4 4 0 Acyl-CoA carboxylase epsilon subunit OAD_gamma PF04277.13 GBG80836.1 - 3.7 8.2 11.5 2.8 8.6 0.1 2.9 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain CDC45 PF02724.14 GBG80836.1 - 4.6 5.4 15.0 6.5 4.9 15.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Atg14 PF10186.9 GBG80836.1 - 4.7 6.2 15.9 6.7 5.7 15.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GREB1 PF15782.5 GBG80837.1 - 0.25 8.4 42.5 0.3 8.1 42.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PPR_1 PF12854.7 GBG80838.1 - 1.6e-93 306.1 1.7 4.5e-11 42.3 0.0 10.7 10 0 0 10 10 10 10 PPR repeat PPR_2 PF13041.6 GBG80838.1 - 1.9e-87 287.3 8.7 2.3e-17 62.9 0.0 10.7 3 2 7 10 10 10 10 PPR repeat family PPR PF01535.20 GBG80838.1 - 1.7e-81 263.0 13.8 3.9e-09 36.2 0.0 11.0 10 0 0 10 10 10 10 PPR repeat PPR_3 PF13812.6 GBG80838.1 - 6.8e-63 208.6 0.0 6.2e-13 48.6 0.0 7.6 4 2 3 8 8 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG80838.1 - 1.2e-26 93.4 0.0 1.4e-09 37.6 0.0 3.7 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG80838.1 - 0.00013 22.4 3.8 0.18 12.4 0.0 4.8 4 2 4 8 8 8 1 Tetratricopeptide repeat Smr PF01713.21 GBG80838.1 - 0.0082 16.5 0.0 0.025 14.9 0.0 1.9 1 0 0 1 1 1 1 Smr domain TPR_12 PF13424.6 GBG80838.1 - 0.072 13.4 3.8 12 6.3 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG80839.1 - 9.5e-23 80.9 0.0 1.7e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80839.1 - 2.1e-15 56.6 0.0 5.6e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80839.1 - 1.6e-07 31.5 0.0 3.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG80839.1 - 3.7e-07 30.0 0.0 7.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80839.1 - 1.5e-06 28.7 0.0 3.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80839.1 - 8.5e-05 23.0 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG80840.1 - 1.2e-15 57.7 0.0 5.3e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAPS PF04499.15 GBG80840.1 - 0.15 10.8 6.0 0.052 12.3 1.3 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 GBG80840.1 - 8.5 6.1 11.8 19 5.0 11.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cwf_Cwc_15 PF04889.12 GBG80840.1 - 9.1 5.9 17.9 0.75 9.5 12.9 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RT_RNaseH_2 PF17919.1 GBG80841.1 - 2e-24 85.5 0.0 3.3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80841.1 - 4.2e-23 81.6 0.0 7.1e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80841.1 - 3.3e-09 36.6 0.1 4.8e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cnd1 PF12717.7 GBG80842.1 - 3.5e-22 79.2 1.5 1.2e-17 64.5 0.1 3.2 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 GBG80842.1 - 7.1e-05 22.1 1.0 0.00013 21.2 0.2 1.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 GBG80842.1 - 0.36 11.4 6.1 4.1 8.0 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat RT_RNaseH_2 PF17919.1 GBG80844.1 - 5.3e-33 113.0 0.0 9.2e-33 112.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80844.1 - 7.9e-21 74.3 0.0 1.5e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80844.1 - 5.9e-07 29.2 0.0 8.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-B_dimeris PF09026.10 GBG80845.1 - 1.5 9.3 7.2 14 6.1 0.2 3.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TPR_2 PF07719.17 GBG80845.1 - 1.9 8.8 5.8 0.88 9.8 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 GBG80846.1 - 2e-11 43.8 0.0 4.5e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG80846.1 - 1e-08 34.9 1.5 2.5e-08 33.6 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG80846.1 - 2.4e-05 24.8 0.2 6.5e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG80846.1 - 0.00033 20.4 2.0 0.00074 19.3 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG80846.1 - 0.0014 19.2 0.1 0.0034 18.0 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG80846.1 - 0.051 13.4 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Aspartyl protease Thioredoxin_7 PF13899.6 GBG80849.1 - 3.9e-06 27.0 0.0 9.9e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GBG80849.1 - 0.0013 19.2 0.1 0.0027 18.1 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Prothymosin PF03247.14 GBG80851.1 - 0.0011 19.4 62.1 0.12 12.8 27.3 2.3 2 0 0 2 2 2 2 Prothymosin/parathymosin family RNA_pol_3_Rpc31 PF11705.8 GBG80851.1 - 0.74 10.0 64.6 0.13 12.5 26.9 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.12 GBG80851.1 - 1.9 7.8 46.4 3.1 7.1 19.5 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 GBG80851.1 - 3.8 6.6 33.6 2.3 7.3 11.9 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4746 PF15928.5 GBG80851.1 - 5 6.5 54.1 0.87 8.9 22.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 GBG80852.1 - 0.17 10.1 41.4 0.22 9.7 41.4 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG80852.1 - 0.56 9.6 45.1 1 8.7 45.1 1.5 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG80852.1 - 0.57 8.9 14.6 0.76 8.5 14.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIS_C PF01096.18 GBG80853.1 - 5e-16 58.3 8.4 6.7e-16 57.9 8.4 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Acylphosphatase PF00708.18 GBG80856.1 - 3.5e-12 46.6 1.8 5.3e-12 46.0 0.2 2.1 2 0 0 2 2 2 1 Acylphosphatase Retrotrans_gag PF03732.17 GBG80856.1 - 0.0021 18.3 1.1 0.011 16.0 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Lipin_mid PF16876.5 GBG80856.1 - 0.033 14.3 0.6 0.15 12.2 0.0 2.4 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain TFIIA PF03153.13 GBG80857.1 - 0.00018 21.6 11.6 0.00027 21.1 11.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Tub_N PF16322.5 GBG80857.1 - 0.0017 18.8 19.6 0.0031 18.0 19.6 1.4 1 0 0 1 1 1 1 Tubby N-terminal Presenilin PF01080.17 GBG80857.1 - 1.2 7.8 18.0 2 7.1 18.0 1.3 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 GBG80857.1 - 7.5 5.0 16.6 10 4.5 16.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GBG80857.1 - 9.3 4.3 33.0 14 3.8 33.0 1.4 1 0 0 1 1 1 0 Nop14-like family Arm PF00514.23 GBG80859.1 - 9.2e-40 133.5 7.4 6.8e-11 41.8 0.3 6.6 6 0 0 6 6 6 6 Armadillo/beta-catenin-like repeat U-box PF04564.15 GBG80859.1 - 8.2e-21 74.0 0.0 7.9e-20 70.8 0.0 2.6 2 0 0 2 2 2 1 U-box domain HEAT_2 PF13646.6 GBG80859.1 - 2.8e-10 40.5 8.6 0.00036 20.8 0.5 3.8 2 2 1 3 3 3 3 HEAT repeats Arm_2 PF04826.13 GBG80859.1 - 0.00013 21.5 0.1 0.0021 17.6 0.0 2.6 1 1 0 2 2 2 1 Armadillo-like HEAT_EZ PF13513.6 GBG80859.1 - 0.0003 21.2 7.8 0.26 11.9 0.1 5.0 5 0 0 5 5 4 2 HEAT-like repeat KAP PF05804.12 GBG80859.1 - 0.00059 18.1 0.0 0.17 10.0 0.0 2.1 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) DUF3361 PF11841.8 GBG80859.1 - 0.00083 19.3 0.3 0.025 14.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) zf-Nse PF11789.8 GBG80859.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Neurochondrin PF05536.11 GBG80859.1 - 0.0036 15.8 0.6 0.24 9.7 0.1 2.2 2 0 0 2 2 2 2 Neurochondrin HEAT PF02985.22 GBG80859.1 - 0.004 17.3 3.2 2.4 8.6 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat RPW8 PF05659.11 GBG80859.1 - 0.013 15.2 0.9 0.026 14.2 0.2 1.8 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tcp11 PF05794.13 GBG80859.1 - 0.028 13.5 0.1 0.45 9.5 0.0 2.1 2 0 0 2 2 2 0 T-complex protein 11 Arm PF00514.23 GBG80861.1 - 2.7e-41 138.3 5.2 8.5e-11 41.5 0.2 6.7 6 0 0 6 6 6 6 Armadillo/beta-catenin-like repeat U-box PF04564.15 GBG80861.1 - 1.7e-20 73.0 0.2 2.2e-19 69.4 0.0 2.8 3 0 0 3 3 3 1 U-box domain HEAT_2 PF13646.6 GBG80861.1 - 1.7e-08 34.7 13.6 0.00092 19.6 0.3 4.8 3 2 1 4 4 4 3 HEAT repeats Arm_2 PF04826.13 GBG80861.1 - 6.6e-05 22.5 0.0 0.00025 20.6 0.0 1.9 1 1 0 1 1 1 1 Armadillo-like KAP PF05804.12 GBG80861.1 - 0.00085 17.6 0.0 0.25 9.5 0.0 2.3 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) zf-Nse PF11789.8 GBG80861.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Neurochondrin PF05536.11 GBG80861.1 - 0.0021 16.5 0.7 0.13 10.6 0.1 2.3 2 0 0 2 2 2 2 Neurochondrin RPW8 PF05659.11 GBG80861.1 - 0.0041 16.8 0.8 0.0073 16.0 0.8 1.5 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 HEAT PF02985.22 GBG80861.1 - 0.0085 16.3 4.2 4.9 7.7 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat Phage_CP76 PF06892.11 GBG80861.1 - 0.015 14.9 0.0 4.4 6.8 0.0 2.7 2 0 0 2 2 2 0 Phage regulatory protein CII (CP76) MtrA PF04208.14 GBG80861.1 - 0.063 12.9 0.0 0.87 9.2 0.0 2.4 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit A DUF3361 PF11841.8 GBG80861.1 - 0.12 12.3 0.9 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) HEAT_EZ PF13513.6 GBG80861.1 - 2.9 8.5 12.2 4 8.1 0.1 4.9 4 2 2 6 6 6 0 HEAT-like repeat RT_RNaseH PF17917.1 GBG80862.1 - 3e-18 66.0 0.5 1.2e-17 64.0 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80862.1 - 2.6e-12 46.6 0.1 7.4e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80862.1 - 0.022 15.0 0.0 0.091 13.0 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein Phage_GPO PF05929.11 GBG80862.1 - 0.079 12.6 3.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Retrotrans_gag PF03732.17 GBG80863.1 - 0.035 14.4 2.8 0.14 12.4 0.2 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein Lipin_mid PF16876.5 GBG80863.1 - 0.068 13.3 1.3 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain CCSAP PF15748.5 GBG80864.1 - 0.016 15.4 19.1 0.016 15.4 19.1 2.1 1 1 1 2 2 2 0 Centriole, cilia and spindle-associated Hid1 PF12722.7 GBG80864.1 - 1.1 7.3 35.2 1.3 7.1 35.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RVT_1 PF00078.27 GBG80866.1 - 3e-27 95.6 0.1 5.3e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80866.1 - 2.1e-26 91.9 0.0 4.5e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80866.1 - 2.2e-24 85.7 0.0 4.8e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80866.1 - 0.00052 20.2 0.1 0.0032 17.7 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG80866.1 - 0.0052 17.4 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80866.1 - 0.011 16.2 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG80866.1 - 0.013 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Cwf_Cwc_15 PF04889.12 GBG80866.1 - 0.44 10.2 34.4 1.1 8.9 7.8 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 GBG80866.1 - 1.1 9.4 55.8 4.3 7.5 17.8 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 GBG80866.1 - 2.7 7.3 59.6 0.057 12.8 16.2 2.4 2 0 0 2 2 2 0 SDA1 NPR3 PF03666.13 GBG80866.1 - 3.3 6.4 22.5 2 7.1 1.9 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.7 GBG80866.1 - 6.5 6.5 25.9 0.1 12.4 1.0 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Pro_isomerase PF00160.21 GBG80867.1 - 1.4e-12 48.2 0.0 2.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3446 PF11928.8 GBG80867.1 - 1.7 9.0 10.6 3.2 8.1 0.5 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Pro_isomerase PF00160.21 GBG80868.1 - 0.00067 20.0 0.7 0.002 18.4 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arm PF00514.23 GBG80869.1 - 3.5e-41 138.0 5.2 8.2e-11 41.6 0.2 6.7 6 0 0 6 6 6 6 Armadillo/beta-catenin-like repeat U-box PF04564.15 GBG80869.1 - 6.1e-21 74.4 0.1 3.5e-19 68.7 0.0 2.9 3 0 0 3 3 3 1 U-box domain HEAT_2 PF13646.6 GBG80869.1 - 7.8e-09 35.8 11.4 0.00087 19.6 0.3 4.3 2 2 2 4 4 4 2 HEAT repeats Arm_2 PF04826.13 GBG80869.1 - 4.7e-05 23.0 0.0 0.00019 21.0 0.0 2.0 1 1 1 2 2 2 1 Armadillo-like zf-RING_UBOX PF13445.6 GBG80869.1 - 0.00021 21.2 0.1 0.00041 20.3 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 GBG80869.1 - 0.00052 19.8 0.1 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit KAP PF05804.12 GBG80869.1 - 0.001 17.3 0.0 0.3 9.2 0.0 2.1 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) zf-C3HC4_2 PF13923.6 GBG80869.1 - 0.0011 18.8 0.1 0.0024 17.6 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RPW8 PF05659.11 GBG80869.1 - 0.0015 18.3 1.3 0.0027 17.4 1.3 1.5 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 zf-C3HC4_4 PF15227.6 GBG80869.1 - 0.0017 18.4 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Neurochondrin PF05536.11 GBG80869.1 - 0.0019 16.6 0.7 0.12 10.7 0.1 2.3 2 0 0 2 2 2 1 Neurochondrin HEAT PF02985.22 GBG80869.1 - 0.0073 16.5 4.2 4.7 7.7 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat zf-rbx1 PF12678.7 GBG80869.1 - 0.048 14.0 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain MtrA PF04208.14 GBG80869.1 - 0.049 13.3 0.0 0.69 9.5 0.0 2.5 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit A zf-RING_2 PF13639.6 GBG80869.1 - 0.058 13.7 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain DUF3361 PF11841.8 GBG80869.1 - 0.093 12.7 0.7 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) HEAT_EZ PF13513.6 GBG80869.1 - 2.2 8.9 12.0 3.8 8.1 0.1 4.8 4 1 1 5 5 5 0 HEAT-like repeat Integrase_H2C2 PF17921.1 GBG80871.1 - 1.2e-18 67.0 0.8 2.6e-18 65.9 0.8 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG80871.1 - 2.8e-17 62.9 0.0 7.7e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80871.1 - 4.2e-16 59.2 0.0 1.2e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG80871.1 - 4.2e-16 58.8 0.0 9e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG80871.1 - 3.2e-06 27.6 0.1 8.4e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80871.1 - 0.0001 22.9 0.1 0.00024 21.7 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80871.1 - 0.0032 17.3 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG80871.1 - 0.053 13.6 0.7 0.13 12.4 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2 PF09337.10 GBG80871.1 - 0.076 13.2 0.2 0.17 12.2 0.2 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 GBG80871.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG80872.1 - 0.13 12.5 0.0 0.35 11.2 0.0 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein API5 PF05918.11 GBG80872.1 - 1.6 7.4 3.5 28 3.3 0.0 2.4 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Topo_Zn_Ribbon PF08272.11 GBG80873.1 - 0.083 12.6 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVT_1 PF00078.27 GBG80874.1 - 0.16 11.4 0.1 11 5.4 0.0 2.8 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) Hist_deacetyl PF00850.19 GBG80875.1 - 1.6e-82 277.5 1.0 2e-82 277.1 1.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RVT_1 PF00078.27 GBG80876.1 - 1.2e-34 119.8 0.0 1.9e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80876.1 - 6.8e-19 67.8 0.0 2.1e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80876.1 - 1.4e-08 35.0 0.0 4.2e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PIEZO PF15917.5 GBG80876.1 - 0.42 10.1 8.6 0.59 9.6 7.8 1.5 2 0 0 2 2 2 0 Piezo RFC1 PF08519.12 GBG80878.1 - 4.7e-41 140.6 0.1 8.6e-41 139.7 0.1 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain TFIID-18kDa PF02269.16 GBG80878.1 - 5e-30 103.4 0.3 1.1e-29 102.2 0.3 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit BRCT PF00533.26 GBG80878.1 - 4.5e-18 65.4 0.2 3.8e-17 62.4 0.1 2.5 3 0 0 3 3 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 GBG80878.1 - 3.2e-12 47.0 0.0 8.3e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.7 GBG80878.1 - 6e-06 26.1 0.0 1.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain AAA_22 PF13401.6 GBG80878.1 - 5.1e-05 23.6 0.2 0.0003 21.1 0.0 2.4 3 0 0 3 3 2 1 AAA domain DNA_pol3_delta PF06144.13 GBG80878.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_33 PF13671.6 GBG80878.1 - 0.0016 18.6 0.0 0.01 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GBG80878.1 - 0.0022 18.0 0.0 0.0066 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG80878.1 - 0.003 17.3 0.0 0.0096 15.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 GBG80878.1 - 0.0042 17.0 0.2 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 GBG80878.1 - 0.0043 17.5 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 GBG80878.1 - 0.0069 16.1 0.1 0.019 14.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain BRCT_2 PF16589.5 GBG80878.1 - 0.018 15.5 0.0 0.054 13.9 0.0 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain AAA_assoc_2 PF16193.5 GBG80878.1 - 0.018 15.3 0.1 0.068 13.5 0.1 2.0 1 0 0 1 1 1 0 AAA C-terminal domain Zeta_toxin PF06414.12 GBG80878.1 - 0.024 13.9 0.1 0.062 12.6 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 GBG80878.1 - 0.027 14.4 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 GBG80878.1 - 0.042 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pyr_redox PF00070.27 GBG80878.1 - 0.069 13.7 0.5 1.1 9.9 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TsaE PF02367.17 GBG80878.1 - 0.093 12.7 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 GBG80878.1 - 0.094 13.3 1.3 0.27 11.8 0.1 2.4 3 0 0 3 3 1 0 AAA domain AAA_6 PF12774.7 GBG80878.1 - 0.098 11.6 0.2 0.18 10.7 0.2 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 GBG80878.1 - 0.16 12.4 0.0 0.48 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PBP1_TM PF14812.6 GBG80878.1 - 8.2 6.9 6.9 3.3 8.2 1.8 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GRP PF07172.11 GBG80880.1 - 0.11 13.2 28.5 0.13 13.0 28.5 1.1 1 0 0 1 1 1 0 Glycine rich protein family Oxysterol_BP PF01237.18 GBG80880.1 - 2.9 6.6 6.1 3.2 6.5 6.1 1.0 1 0 0 1 1 1 0 Oxysterol-binding protein SR-25 PF10500.9 GBG80881.1 - 0.14 11.7 26.2 0.24 11.0 25.9 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 GBG80881.1 - 0.26 9.8 12.0 0.32 9.5 12.0 1.0 1 0 0 1 1 1 0 Macoilin family A_deamin PF02137.18 GBG80881.1 - 1.2 8.5 4.5 1.6 8.1 4.5 1.2 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain BUD22 PF09073.10 GBG80881.1 - 3.5 6.9 51.1 0.074 12.4 43.6 1.8 2 0 0 2 2 2 0 BUD22 Presenilin PF01080.17 GBG80881.1 - 7.6 5.2 28.0 0.45 9.2 0.6 2.1 2 0 0 2 2 2 0 Presenilin RVT_1 PF00078.27 GBG80882.1 - 1.1e-24 87.2 0.0 1.9e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80882.1 - 1.4e-24 86.4 0.0 4e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80882.1 - 1.3e-22 79.7 0.0 3.8e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG80882.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RabGAP-TBC PF00566.18 GBG80883.1 - 6.8e-31 107.6 0.5 4.7e-28 98.3 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Synaptobrevin PF00957.21 GBG80884.1 - 5.9e-15 54.8 0.5 8.9e-15 54.3 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GBG80884.1 - 9.6e-12 44.8 0.0 1.7e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2199 PF09965.9 GBG80884.1 - 0.071 13.2 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) CPSF73-100_C PF11718.8 GBG80885.1 - 4.3e-49 167.0 3.5 1.8e-48 164.9 1.4 2.1 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 GBG80885.1 - 6.7e-31 106.8 0.0 1.3e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 GBG80885.1 - 6.9e-21 75.2 0.1 1.1e-20 74.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 GBG80885.1 - 5.6e-17 61.4 0.0 1.1e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 GBG80885.1 - 3.6e-16 59.2 0.1 2.5e-15 56.4 0.0 2.1 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 GBG80885.1 - 2.6e-07 30.3 3.6 1.9e-06 27.5 0.2 3.1 3 1 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GBG80885.1 - 1.6e-05 24.8 0.8 0.00039 20.4 0.0 3.2 3 1 0 3 3 3 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 GBG80885.1 - 2e-05 23.9 0.0 4.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Putative beta-lactamase-like family DUF4239 PF14023.6 GBG80885.1 - 0.052 13.3 0.2 0.096 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) WD40 PF00400.32 GBG80886.1 - 2.2e-33 113.7 3.1 1.1e-07 32.4 0.3 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG80886.1 - 1.8e-12 47.3 0.0 0.081 13.2 0.0 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG80886.1 - 0.0008 18.5 0.6 8.9 5.2 0.1 3.7 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GBG80886.1 - 0.0023 16.7 0.0 0.027 13.1 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.11 GBG80886.1 - 0.0031 17.4 0.0 1.1 9.1 0.0 3.3 1 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 GBG80886.1 - 0.0064 16.1 0.1 0.097 12.2 0.1 2.1 1 1 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 GBG80886.1 - 0.074 12.4 0.0 0.71 9.1 0.0 2.4 3 1 0 3 3 3 0 WD40-like domain RT_RNaseH_2 PF17919.1 GBG80887.1 - 1.8e-30 104.9 0.0 7.3e-15 54.8 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80887.1 - 6.6e-29 100.3 0.0 1.5e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80887.1 - 1.6e-27 96.5 0.0 3.1e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80887.1 - 2.9e-13 49.7 1.7 5.5e-13 48.8 0.1 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG80887.1 - 3.5e-11 43.3 0.0 1.6e-10 41.2 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG80887.1 - 4.2e-11 42.6 0.0 9.7e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG80887.1 - 0.016 15.8 0.0 0.049 14.3 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG80887.1 - 0.027 14.7 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG80888.1 - 3.3e-07 30.8 0.1 9.6e-07 29.3 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80888.1 - 1.8e-05 25.3 0.1 5.3e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80888.1 - 0.00093 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG80888.1 - 0.12 12.5 3.0 0.16 12.1 1.9 1.8 2 0 0 2 2 2 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG80888.1 - 0.15 11.8 0.7 0.34 10.6 0.1 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Myb_DNA-bind_4 PF13837.6 GBG80889.1 - 9.8e-09 35.5 0.9 3.8e-08 33.6 0.3 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG80889.1 - 0.023 15.0 0.1 0.072 13.4 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CTP_transf_3 PF02348.19 GBG80890.1 - 4.4e-51 173.9 0.0 5.6e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 GBG80890.1 - 2e-09 38.0 0.0 3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain ADH_zinc_N PF00107.26 GBG80890.1 - 0.00061 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IspD PF01128.19 GBG80890.1 - 0.0041 16.9 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF2064 PF09837.9 GBG80890.1 - 0.083 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) Lant_dehydr_N PF04738.13 GBG80890.1 - 0.16 10.0 0.0 0.24 9.5 0.0 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus Lipase_GDSL PF00657.22 GBG80892.1 - 6.8e-13 49.1 0.0 9.3e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PRIMA1 PF16101.5 GBG80892.1 - 0.4 10.7 3.3 0.9 9.6 3.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 GBG80892.1 - 0.57 10.2 1.9 0.87 9.6 1.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Integrase_H2C2 PF17921.1 GBG80893.1 - 3.9e-10 39.7 0.1 8.7e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG80893.1 - 5.4e-07 30.1 0.3 1.6e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80893.1 - 0.00021 21.8 0.0 0.00057 20.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80893.1 - 0.0071 16.1 1.1 0.014 15.2 1.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG80893.1 - 0.13 12.5 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease WD40 PF00400.32 GBG80894.1 - 2.6e-09 37.6 2.7 0.021 15.7 0.2 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.7 GBG80894.1 - 1e-07 31.7 1.8 1e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.8 GBG80894.1 - 2.7e-05 23.0 0.7 0.13 10.9 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GBG80894.1 - 5.8e-05 23.3 0.0 0.21 11.9 0.0 3.0 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GBG80894.1 - 0.0012 18.7 0.0 0.0046 16.8 0.0 2.1 1 0 0 1 1 1 1 F-box domain RT_RNaseH PF17917.1 GBG80895.1 - 5.7e-22 78.0 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80895.1 - 1.3e-20 73.3 0.0 2.6e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80895.1 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG80895.1 - 0.0027 18.2 0.4 0.029 14.9 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80895.1 - 0.0043 17.7 0.1 0.033 14.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease CofC PF01983.16 GBG80895.1 - 0.13 11.4 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Guanylyl transferase CofC like RVP PF00077.20 GBG80895.1 - 0.17 12.2 0.0 0.48 10.8 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF659 PF04937.15 GBG80896.1 - 4e-30 104.7 0.1 6.2e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Sec1 PF00995.23 GBG80898.1 - 6.4e-41 141.3 0.0 7e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RVT_1 PF00078.27 GBG80899.1 - 9.3e-28 97.2 0.2 1.7e-27 96.4 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80899.1 - 2.2e-16 59.7 0.0 5.7e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80899.1 - 1e-07 32.2 0.0 2.9e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80899.1 - 0.016 15.5 1.3 7.5 6.9 0.0 3.9 3 0 0 3 3 3 0 Retrotransposon gag protein RNR_Alpha PF17975.1 GBG80899.1 - 0.11 13.0 0.4 0.3 11.6 0.0 2.0 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain RVT_1 PF00078.27 GBG80900.1 - 6.1e-21 75.0 0.1 9.9e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80900.1 - 8.7e-07 29.0 0.1 2.1e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG80900.1 - 0.00085 19.6 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80900.1 - 0.0017 18.4 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80901.1 - 2.5e-13 49.9 0.0 9.4e-13 48.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80901.1 - 4.5e-10 39.4 0.2 0.00064 19.3 0.0 2.6 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80901.1 - 4.9e-05 23.6 0.2 0.00076 19.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80901.1 - 0.00053 20.2 3.4 0.0016 18.7 0.1 3.0 4 0 0 4 4 4 1 Retrotransposon gag protein APG17 PF04108.12 GBG80901.1 - 0.06 12.4 0.1 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 Autophagy protein Apg17 Integrase_H2C2 PF17921.1 GBG80902.1 - 1.7e-16 60.0 0.0 3.8e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80902.1 - 1.8e-12 47.5 0.0 5e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG80902.1 - 0.013 15.5 0.2 0.025 14.6 0.2 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG80902.1 - 0.096 12.5 0.9 2.4 8.0 0.0 3.0 3 0 0 3 3 3 0 Integrase core domain DAPDH_C PF16654.5 GBG80902.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Med8 PF10232.9 GBG80902.1 - 0.62 9.6 6.0 0.97 9.0 0.1 2.8 2 1 1 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 Fib_alpha PF08702.10 GBG80902.1 - 1.8 8.7 5.3 12 6.1 2.5 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RT_RNaseH PF17917.1 GBG80903.1 - 2.6e-25 88.7 0.4 1.2e-24 86.5 0.9 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80903.1 - 6.7e-18 64.6 0.3 1.5e-17 63.4 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80904.1 - 5.1e-30 103.9 0.9 4.8e-29 100.7 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80904.1 - 8.6e-29 99.5 0.0 8.3e-28 96.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80904.1 - 2.3e-16 59.7 1.0 4.8e-16 58.6 1.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80904.1 - 3.1e-14 53.2 0.0 1e-13 51.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG80904.1 - 0.012 15.8 1.1 0.024 14.8 0.2 2.1 2 0 0 2 2 2 0 H2C2 zinc finger Chromo PF00385.24 GBG80904.1 - 0.12 12.3 0.2 0.33 10.9 0.1 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Phage_GPO PF05929.11 GBG80904.1 - 0.14 11.8 1.7 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Casc1_N PF15927.5 GBG80904.1 - 0.45 10.2 8.2 1.2 8.8 8.2 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Integrase_H2C2 PF17921.1 GBG80905.1 - 1.5e-18 66.7 0.3 4.2e-18 65.2 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG80905.1 - 7.9e-18 64.7 0.4 2.3e-17 63.2 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80905.1 - 1.5e-10 41.0 0.0 3.6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG80905.1 - 3.5e-05 23.5 0.1 7.9e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG80905.1 - 4.6e-05 23.3 0.0 9.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG80905.1 - 0.011 16.0 0.0 0.03 14.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 GBG80905.1 - 0.027 14.7 0.0 0.083 13.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger LEA_5 PF00477.17 GBG80906.1 - 0.34 11.4 6.0 3.8 8.0 0.1 3.1 3 0 0 3 3 3 0 Small hydrophilic plant seed protein AAA_6 PF12774.7 GBG80907.1 - 2.2e-25 89.3 0.0 4.3e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DNA_pol3_theta PF06440.11 GBG80907.1 - 0.073 12.7 0.5 0.2 11.3 0.5 1.7 1 1 0 1 1 1 0 DNA polymerase III, theta subunit zf-CCHC PF00098.23 GBG80908.1 - 4.7e-06 26.4 4.3 5.1e-06 26.3 2.5 2.1 2 0 0 2 2 2 1 Zinc knuckle Alanine_zipper PF11839.8 GBG80908.1 - 0.0025 18.1 18.5 0.0059 16.9 18.5 1.6 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein Prok-RING_1 PF14446.6 GBG80908.1 - 0.05 13.5 0.5 0.05 13.5 0.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-CCHC_2 PF13696.6 GBG80908.1 - 3 7.8 8.2 0.51 10.2 2.0 2.4 2 0 0 2 2 2 0 Zinc knuckle SDA1 PF05285.12 GBG80909.1 - 0.82 9.0 44.9 0.18 11.2 34.1 2.2 2 0 0 2 2 2 0 SDA1 Nop53 PF07767.11 GBG80909.1 - 7.1 5.9 41.6 0.093 12.1 29.3 2.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF659 PF04937.15 GBG80910.1 - 3.2e-19 69.3 0.0 5.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) TT_ORF2 PF02957.15 GBG80910.1 - 0.17 12.8 2.0 3.8 8.4 0.6 2.7 2 0 0 2 2 2 0 TT viral ORF2 RVT_1 PF00078.27 GBG80912.1 - 9.5e-10 38.4 0.2 2.7e-09 36.9 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80912.1 - 1.6e-08 34.5 0.0 5.2e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80912.1 - 0.00075 19.8 0.1 0.012 15.9 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG80912.1 - 0.072 13.4 5.0 10 6.4 0.0 4.8 5 0 0 5 5 5 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG80913.1 - 6.4e-30 103.2 0.0 2.3e-29 101.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80913.1 - 1.7e-28 98.9 2.4 1.9e-28 98.8 0.1 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80913.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG80913.1 - 0.28 10.8 0.0 0.28 10.8 0.0 3.1 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3138 PF11336.8 GBG80913.1 - 1.6 7.2 2.9 2.6 6.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3629 PF12302.8 GBG80913.1 - 1.9 7.9 9.4 5.2 6.4 9.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) AAA_6 PF12774.7 GBG80914.1 - 7.1e-99 330.9 0.1 1.2e-98 330.2 0.1 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region RVT_1 PF00078.27 GBG80914.1 - 3e-25 89.0 0.1 4.8e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_5 PF07728.14 GBG80914.1 - 0.00093 19.2 0.1 0.2 11.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 GBG80914.1 - 0.02 15.3 0.1 0.23 11.9 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) tRNA-synt_1_2 PF13603.6 GBG80914.1 - 0.057 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 AAA_18 PF13238.6 GBG80914.1 - 0.18 12.4 4.7 0.45 11.1 0.0 3.3 3 1 0 3 3 3 0 AAA domain LMBR1 PF04791.16 GBG80914.1 - 6.4 5.6 7.0 10 4.9 7.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RVT_1 PF00078.27 GBG80915.1 - 6.4e-58 195.9 0.3 3.8e-29 101.8 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80915.1 - 3.6e-49 164.9 0.0 2e-26 91.9 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80915.1 - 7.5e-36 122.6 0.0 3.2e-19 69.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80915.1 - 6.4e-21 74.7 0.8 3.8e-09 36.8 0.0 3.9 4 0 0 4 4 4 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG80915.1 - 2.2e-18 66.1 0.4 2e-17 63.0 0.2 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain Tudor-knot PF11717.8 GBG80915.1 - 0.00022 21.0 0.0 0.00071 19.4 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Retrotrans_gag PF03732.17 GBG80915.1 - 0.014 15.7 0.0 0.072 13.4 0.0 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein DUF3245 PF11595.8 GBG80915.1 - 1.7 9.1 6.7 0.59 10.6 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Cwf_Cwc_15 PF04889.12 GBG80915.1 - 7.4 6.2 22.9 0.76 9.5 3.3 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RT_RNaseH_2 PF17919.1 GBG80916.1 - 4.9e-18 65.0 0.0 9.9e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80916.1 - 7.9e-15 55.0 0.0 2.1e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80916.1 - 6.2e-08 32.8 0.0 1.7e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF4559 PF15112.6 GBG80916.1 - 1.5 8.4 5.4 3.2 7.4 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) RVT_1 PF00078.27 GBG80917.1 - 1.2e-22 80.6 0.1 2.1e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80917.1 - 0.0013 18.5 0.0 0.0044 16.8 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease DHC_N2 PF08393.13 GBG80918.1 - 1.2e-25 90.5 0.2 2.1e-25 89.7 0.2 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 RT_RNaseH PF17917.1 GBG80918.1 - 2.6e-23 82.3 0.1 1.1e-22 80.3 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80918.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG80918.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG80920.1 - 3.2e-20 72.0 0.0 8.1e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80920.1 - 3e-18 66.0 0.0 3.8e-17 62.5 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80920.1 - 9.4e-05 22.0 0.0 0.00033 20.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG80920.1 - 0.00079 19.6 1.3 0.0035 17.6 0.3 2.5 2 1 1 3 3 3 1 Retrotransposon gag protein Pro-rich PF15240.6 GBG80920.1 - 0.027 14.8 2.6 0.046 14.0 2.6 1.3 1 0 0 1 1 1 0 Proline-rich DUF1664 PF07889.12 GBG80920.1 - 0.12 12.4 2.7 3.7 7.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) RT_RNaseH_2 PF17919.1 GBG80921.1 - 2.7e-31 107.6 0.0 1.3e-30 105.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80921.1 - 2.6e-29 101.6 0.0 7.8e-29 100.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Es2 PF09751.9 GBG80921.1 - 0.43 10.3 12.3 0.68 9.6 12.3 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 RT_RNaseH_2 PF17919.1 GBG80922.1 - 1.2e-31 108.6 0.0 2.2e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80922.1 - 2.8e-31 108.8 0.1 4.9e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80922.1 - 2.2e-27 95.4 0.1 4.2e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rhamno_transf PF11316.8 GBG80922.1 - 0.038 13.4 0.1 0.083 12.3 0.0 1.5 2 0 0 2 2 2 0 Putative rhamnosyl transferase RVT_1 PF00078.27 GBG80923.1 - 1.7e-29 102.9 0.1 4e-23 82.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80923.1 - 2.2e-24 85.4 0.0 5.7e-24 84.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80923.1 - 1.6e-22 79.7 0.0 4.4e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80923.1 - 1.1e-19 70.2 0.3 2.7e-19 69.0 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG80923.1 - 1.8e-10 41.3 0.0 4.7e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG80923.1 - 8.3e-08 32.7 0.0 2.7e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80923.1 - 3e-05 23.8 0.0 0.00038 20.2 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80923.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG80923.1 - 0.002 18.4 6.0 0.0034 17.6 0.2 3.5 4 0 0 4 4 4 1 Retrotransposon gag protein Chromo PF00385.24 GBG80923.1 - 0.012 15.5 0.1 0.03 14.2 0.1 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DDE_Tnp_4 PF13359.6 GBG80924.1 - 2.1e-21 76.2 0.0 4.9e-21 75.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80924.1 - 2e-10 40.7 0.0 3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG80925.1 - 3.2e-09 37.1 6.3 8.1e-08 32.5 3.8 2.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG80925.1 - 0.021 15.1 5.2 0.028 14.7 2.3 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LapA_dom PF06305.11 GBG80925.1 - 0.04 13.7 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain YajC PF02699.15 GBG80925.1 - 0.084 12.8 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit LAP1C PF05609.12 GBG80926.1 - 0.02 14.0 23.6 0.028 13.5 23.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NOA36 PF06524.12 GBG80926.1 - 1.2 8.4 14.7 2.5 7.3 14.7 1.5 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.9 GBG80926.1 - 4 5.1 15.2 5.4 4.7 15.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RT_RNaseH_2 PF17919.1 GBG80927.1 - 6.3e-24 83.9 0.0 2.2e-23 82.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80927.1 - 3.1e-22 78.8 0.0 1.1e-21 77.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80927.1 - 1.2e-07 31.4 0.3 2.6e-05 23.8 0.2 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80928.1 - 7.9e-59 196.5 2.2 1.9e-20 73.1 0.0 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80928.1 - 8e-47 157.4 0.0 5.5e-18 64.9 0.0 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80928.1 - 6.2e-34 115.9 10.5 1.8e-17 63.2 0.2 3.9 3 0 0 3 3 3 3 Integrase zinc binding domain rve PF00665.26 GBG80928.1 - 1.9e-15 57.1 1.0 3e-08 33.9 0.0 4.0 4 0 0 4 4 4 3 Integrase core domain rve_3 PF13683.6 GBG80928.1 - 0.0011 18.7 0.0 0.77 9.6 0.0 3.0 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG80928.1 - 0.0015 18.0 0.0 0.0036 16.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG80928.1 - 0.009 16.3 0.2 0.009 16.3 0.2 3.5 4 0 0 4 4 4 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG80928.1 - 0.14 12.4 0.0 3.6 7.9 0.0 3.1 3 0 0 3 3 3 0 H2C2 zinc finger Rhamno_transf PF11316.8 GBG80928.1 - 0.51 9.7 6.3 1.2 8.5 0.0 3.2 4 0 0 4 4 4 0 Putative rhamnosyl transferase RT_RNaseH_2 PF17919.1 GBG80929.1 - 2.3e-52 175.2 0.0 2.7e-30 104.4 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80929.1 - 3.3e-51 172.0 0.1 8.8e-28 96.7 0.1 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80929.1 - 2.8e-24 85.9 0.1 6e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80929.1 - 1.7e-17 63.2 0.2 4.2e-17 62.0 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG80929.1 - 4.7e-15 55.8 0.4 2.5e-14 53.5 0.1 2.5 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG80929.1 - 1.2e-05 25.5 7.4 0.011 16.0 0.1 3.9 4 0 0 4 4 4 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG80929.1 - 0.01 16.0 0.0 0.038 14.2 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG80930.1 - 3.6e-90 301.3 9.7 3.1e-34 118.4 0.1 4.4 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG80930.1 - 7.7e-49 164.4 0.3 9.2e-29 99.8 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80930.1 - 1.7e-40 137.1 0.4 9.6e-29 99.4 0.0 3.4 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80930.1 - 1.6e-09 37.7 0.0 4.4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG80930.1 - 4e-06 27.4 0.0 1.2e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80930.1 - 4.6e-06 27.1 0.0 1.5e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80930.1 - 5.3e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG80930.1 - 0.00012 21.9 0.0 0.00033 20.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Trans_reg_C PF00486.28 GBG80930.1 - 0.27 11.4 1.2 14 5.8 0.1 2.9 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal GIY-YIG PF01541.24 GBG80931.1 - 2.9e-08 33.8 0.6 1.2e-07 31.9 0.0 2.5 2 0 0 2 2 2 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG80931.1 - 1.8e-06 27.8 1.5 3.6e-06 26.8 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG80931.1 - 2.8e-05 24.3 0.1 0.017 15.4 0.4 3.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.6 GBG80931.1 - 0.014 15.1 2.1 0.031 14.0 2.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RT_RNaseH_2 PF17919.1 GBG80932.1 - 2e-22 79.1 0.0 3.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80932.1 - 7.7e-21 74.4 0.0 1.4e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80932.1 - 3.9e-17 62.5 1.0 2.7e-08 33.6 0.1 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG80932.1 - 5.1e-14 52.1 1.7 1.3e-13 50.8 0.6 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain DHC_N2 PF08393.13 GBG80932.1 - 3.6e-08 32.9 0.0 1.1e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 rve PF00665.26 GBG80932.1 - 4.8e-07 30.0 0.0 1.5e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG80932.1 - 2.7e-05 24.0 0.0 0.00044 20.0 0.0 2.4 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG80932.1 - 0.00068 20.2 0.0 0.0022 18.5 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80932.1 - 0.0036 17.9 0.0 0.024 15.3 0.0 2.2 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG80932.1 - 0.0043 16.8 0.1 0.018 14.9 0.1 1.9 1 1 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG80932.1 - 0.079 13.2 0.3 0.23 11.7 0.3 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Pox_A_type_inc PF04508.12 GBG80933.1 - 0.001 18.8 4.4 3.8 7.5 2.1 5.3 6 0 0 6 6 6 1 Viral A-type inclusion protein repeat TolA_bind_tri PF16331.5 GBG80933.1 - 0.0012 18.8 2.7 0.97 9.6 0.2 3.9 3 0 0 3 3 3 2 TolA binding protein trimerisation DUF455 PF04305.14 GBG80933.1 - 0.0085 15.7 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF455) Orbi_NS3 PF01616.16 GBG80933.1 - 0.014 15.1 0.6 3.4 7.3 0.1 2.5 2 0 0 2 2 2 0 Orbivirus NS3 Prp19 PF08606.11 GBG80933.1 - 0.031 14.3 0.0 0.18 11.8 0.0 2.3 1 0 0 1 1 1 0 Prp19/Pso4-like Mu-like_Pro PF10123.9 GBG80933.1 - 0.04 13.5 5.6 0.59 9.6 1.7 2.4 2 0 0 2 2 2 0 Mu-like prophage I protein IGR PF09597.10 GBG80933.1 - 0.32 11.1 2.7 7.6 6.7 0.3 2.5 2 0 0 2 2 2 0 IGR protein motif CAGE1 PF15066.6 GBG80933.1 - 0.44 9.2 11.6 0.16 10.6 1.3 2.6 2 1 0 2 2 2 0 Cancer-associated gene protein 1 family CCDC92 PF14916.6 GBG80933.1 - 0.9 9.4 6.2 21 5.0 0.3 4.6 4 1 1 5 5 5 0 Coiled-coil domain of unknown function RT_RNaseH PF17917.1 GBG80934.1 - 7.7e-31 106.5 0.0 1.4e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80934.1 - 1.9e-30 104.9 0.0 3.3e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80934.1 - 7.8e-19 67.5 1.7 1.5e-18 66.6 1.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG80934.1 - 0.0013 18.9 0.2 0.0034 17.6 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG80934.1 - 0.0031 17.7 0.0 0.0083 16.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Phage_GPO PF05929.11 GBG80934.1 - 0.027 14.1 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG80934.1 - 0.079 12.5 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_PH PF01138.21 GBG80935.1 - 4.7e-18 66.0 0.0 6.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ChapFlgA_N PF17656.1 GBG80935.1 - 0.032 14.4 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 FlgA N-terminal domain Ribosomal_S13 PF00416.22 GBG80936.1 - 1.2e-29 103.3 4.2 6.5e-28 97.7 4.4 2.3 2 1 0 2 2 2 1 Ribosomal protein S13/S18 PAC1 PF16094.5 GBG80937.1 - 0.0019 17.5 0.1 0.0058 15.8 0.0 1.6 1 1 1 2 2 2 1 Proteasome assembly chaperone 4 CRAL_TRIO PF00650.20 GBG80938.1 - 1.4e-32 112.7 0.1 1.8e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GBG80938.1 - 3.9e-08 33.4 0.3 1.3e-07 31.7 0.3 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GBG80938.1 - 2.3e-06 27.8 0.0 3.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DS PF01916.17 GBG80939.1 - 8e-79 264.9 0.0 1e-78 264.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Hydrolase_3 PF08282.12 GBG80940.1 - 4.9e-45 154.3 0.0 1.6e-31 110.0 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase UPF0054 PF02130.17 GBG80940.1 - 1.2e-35 122.1 0.7 2.2e-35 121.3 0.7 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 S6PP PF05116.13 GBG80940.1 - 1.9e-10 40.7 0.0 4.5e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 GBG80940.1 - 3.7e-08 33.9 0.7 1e-06 29.2 0.7 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GBG80940.1 - 2.8e-05 24.3 0.0 0.16 12.0 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 GBG80940.1 - 0.0031 17.9 0.1 2.7 8.4 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GBG80940.1 - 0.0032 17.6 0.0 0.02 15.0 0.0 2.4 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Trigger_N PF05697.13 GBG80941.1 - 3.2e-10 40.5 0.2 4.8e-10 39.9 0.2 1.2 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) DUF4813 PF16072.5 GBG80941.1 - 0.024 14.3 1.1 0.033 13.9 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Ribosomal_60s PF00428.19 GBG80941.1 - 0.84 10.3 10.2 1.1 9.9 1.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein PHD PF00628.29 GBG80943.1 - 4.4e-07 29.7 4.4 4.4e-07 29.7 4.4 2.8 2 0 0 2 2 1 1 PHD-finger EloA-BP1 PF15870.5 GBG80943.1 - 9.4e-06 26.0 0.3 2.7e-05 24.5 0.3 1.8 1 0 0 1 1 1 1 ElonginA binding-protein 1 zf-RING_2 PF13639.6 GBG80943.1 - 0.00014 22.1 10.6 0.00014 22.1 10.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GBG80943.1 - 0.00032 20.6 10.8 0.00082 19.3 10.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GBG80943.1 - 0.001 18.9 10.6 0.001 18.9 10.6 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG80943.1 - 0.0011 18.8 9.0 0.0025 17.6 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 GBG80943.1 - 0.07 12.7 3.9 0.17 11.5 3.9 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 GBG80943.1 - 0.17 11.8 11.9 0.39 10.6 11.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GBG80943.1 - 0.41 10.5 19.9 0.0078 16.1 12.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 GBG80943.1 - 0.51 10.1 8.8 1.4 8.7 8.8 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_10 PF16685.5 GBG80943.1 - 2.4 8.4 8.3 5.2 7.3 8.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 GBG80943.1 - 3.3 8.1 12.7 0.5 10.7 5.4 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain CBFD_NFYB_HMF PF00808.23 GBG80944.1 - 2.9e-16 59.5 0.2 5.8e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GBG80944.1 - 0.049 14.0 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF3342 PF11822.8 GBG80945.1 - 1.3e-22 79.8 0.0 2.4e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) TMEM107 PF14995.6 GBG80946.1 - 3.4e-26 92.1 8.4 4.7e-26 91.7 8.4 1.2 1 0 0 1 1 1 1 Transmembrane protein TRAM1 PF08390.11 GBG80946.1 - 0.048 13.3 0.2 0.092 12.4 0.2 1.5 1 0 0 1 1 1 0 TRAM1-like protein GIY-YIG PF01541.24 GBG80947.1 - 7.3e-07 29.4 0.6 3.1e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG80947.1 - 0.091 12.9 1.4 0.27 11.4 1.4 1.8 1 0 0 1 1 1 0 Zinc knuckle Folliculin PF11704.8 GBG80947.1 - 3.8 7.4 10.0 17 5.2 4.8 2.7 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport Mobilization_B PF17511.2 GBG80947.1 - 6.3 7.2 7.4 14 6.0 7.4 1.5 1 0 0 1 1 1 0 Mobilization protein B CSN5_C PF18323.1 GBG80947.1 - 8 7.4 7.3 2.5e+02 2.7 5.8 3.0 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Glyco_hydro_77 PF02446.17 GBG80948.1 - 7.9e-147 489.9 0.0 1e-146 489.5 0.0 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase DUF755 PF05501.11 GBG80948.1 - 1.5 9.1 16.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) OCRE PF17780.1 GBG80949.1 - 5.3e-17 61.6 13.5 1.1e-16 60.5 13.5 1.6 1 0 0 1 1 1 1 OCRE domain PRK PF00485.18 GBG80950.1 - 3.7e-26 92.1 0.9 1.4e-25 90.2 0.2 2.2 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.21 GBG80950.1 - 7.4e-19 68.4 0.0 1.3e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 CYTH domain AAA_33 PF13671.6 GBG80950.1 - 0.049 13.8 0.0 0.21 11.8 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 GBG80950.1 - 0.05 14.1 0.0 0.58 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GBG80950.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GBG80950.1 - 0.15 11.2 0.1 0.29 10.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain NARP1 PF12569.8 GBG80951.1 - 0.79 8.6 6.9 1.5 7.6 6.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF659 PF04937.15 GBG80953.1 - 2.9e-34 118.1 0.0 6.5e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG80954.1 - 7.1e-15 54.9 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80954.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80954.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG80954.1 - 1.5 8.2 22.5 2 7.8 22.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG80954.1 - 5.8 6.1 24.5 8.9 5.5 24.5 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG80954.1 - 5.8 5.0 23.9 8.2 4.5 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family PSI_PsaH PF03244.14 GBG80955.1 - 9.3e-52 174.2 0.3 1.1e-51 174.0 0.3 1.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit VI RLAN PF14401.6 GBG80955.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain PepSY_2 PF13670.6 GBG80955.1 - 2.4 8.2 5.1 5.1 7.2 5.1 1.5 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain Alg6_Alg8 PF03155.15 GBG80956.1 - 1.1e-135 453.4 25.0 1.4e-135 453.0 25.0 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family PALP PF00291.25 GBG80957.1 - 2.6e-72 243.7 1.6 3.3e-72 243.4 1.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MOR2-PAG1_mid PF14228.6 GBG80959.1 - 0 1508.4 1.1 0 1086.1 0.1 2.1 1 1 1 2 2 2 2 Cell morphogenesis central region MOR2-PAG1_N PF14222.6 GBG80959.1 - 1.7e-77 261.7 0.0 1.3e-76 258.7 0.0 2.0 1 1 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 GBG80959.1 - 5.9e-61 206.5 2.3 1.6e-60 205.1 0.1 2.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal PPR PF01535.20 GBG80960.1 - 0.0093 16.1 2.1 0.73 10.2 0.4 2.7 2 0 0 2 2 2 1 PPR repeat PPR_long PF17177.4 GBG80960.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP CDC45 PF02724.14 GBG80960.1 - 0.02 13.2 8.1 0.031 12.6 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Coat_F PF07875.12 GBG80960.1 - 0.03 14.5 0.1 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 Coat F domain PPR_2 PF13041.6 GBG80960.1 - 0.074 13.3 0.1 0.41 10.9 0.1 2.4 1 1 2 3 3 3 0 PPR repeat family OSR1_C PF12202.8 GBG80960.1 - 0.081 13.2 0.8 16 5.8 0.6 2.5 1 1 1 2 2 2 0 Oxidative-stress-responsive kinase 1 C-terminal domain DUF4637 PF15470.6 GBG80962.1 - 1.5 8.5 8.0 2.7 7.7 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Myb_DNA-bind_4 PF13837.6 GBG80963.1 - 3.7e-11 43.2 2.7 3.7e-11 43.2 2.7 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG80963.1 - 0.12 12.6 1.1 0.25 11.6 1.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Apolipoprotein PF01442.18 GBG80963.1 - 2 8.3 6.5 1.5 8.7 1.4 2.4 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain MADF_DNA_bdg PF10545.9 GBG80963.1 - 8.7 6.7 6.9 1.6 9.1 0.5 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG80964.1 - 1.4e-20 73.6 0.0 2.2e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG80964.1 - 1.4e-12 47.7 0.0 4.1e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 Plant transposon protein Phosphodiest PF01663.22 GBG80965.1 - 4.9e-08 33.0 0.9 8.7e-08 32.1 0.9 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GBG80965.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Sulfatase RT_RNaseH_2 PF17919.1 GBG80966.1 - 9.4e-12 44.9 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80966.1 - 3.6e-10 40.0 0.0 9.5e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80966.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Topo_Zn_Ribbon PF08272.11 GBG80966.1 - 0.083 12.6 0.0 0.48 10.1 0.2 2.2 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like PhyH PF05721.13 GBG80967.1 - 2.7e-49 168.3 0.0 3.4e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RRM_1 PF00076.22 GBG80968.1 - 0.00011 22.0 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHIPEP PF00771.20 GBG80968.1 - 0.00054 18.6 0.7 0.0007 18.2 0.7 1.2 1 0 0 1 1 1 1 FHIPEP family Zip PF02535.22 GBG80968.1 - 0.54 9.4 3.3 0.65 9.1 3.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Protocadherin PF08374.11 GBG80968.1 - 1.2 9.1 7.1 1.7 8.6 7.1 1.2 1 0 0 1 1 1 0 Protocadherin ALMT PF11744.8 GBG80968.1 - 2.1 7.1 6.5 2.5 6.8 6.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA_11 PF13086.6 GBG80968.1 - 2.8 7.7 11.7 4.1 7.1 11.7 1.3 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 GBG80969.1 - 1.2e-28 100.1 0.0 2e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80969.1 - 0.048 14.3 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease ubiquitin PF00240.23 GBG80970.1 - 4.5e-08 32.7 0.0 6.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 GBG80970.1 - 0.06 14.0 0.1 0.17 12.6 0.1 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 GBG80971.1 - 4.6e-08 32.7 0.0 6.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 GBG80971.1 - 0.062 14.0 0.1 0.17 12.6 0.1 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD LETM1 PF07766.13 GBG80972.1 - 2.6e-85 286.0 7.5 2.6e-85 286.0 7.5 2.9 2 1 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 GBG80972.1 - 2.1e-08 34.5 0.3 2.7e-07 30.9 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG80972.1 - 0.00061 19.5 0.0 0.058 13.4 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 GBG80972.1 - 0.0012 18.2 0.0 0.073 12.7 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 GBG80972.1 - 0.015 14.8 1.0 0.097 12.2 0.0 2.4 2 0 0 2 2 2 0 EF hand SAP PF02037.27 GBG80972.1 - 0.11 12.2 1.6 0.78 9.6 0.0 2.9 3 0 0 3 3 3 0 SAP domain RT_RNaseH_2 PF17919.1 GBG80973.1 - 1.5e-25 89.1 0.0 2.6e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80973.1 - 9.1e-25 87.0 0.0 1.5e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80973.1 - 1.3e-06 28.1 0.1 2.1e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3381 PF11861.8 GBG80973.1 - 1.4 8.7 5.6 2.5 7.9 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FHA PF00498.26 GBG80974.1 - 1.6e-19 70.0 0.0 3.6e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GBG80974.1 - 2.2e-08 34.3 0.0 4.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF2205 PF10224.9 GBG80975.1 - 0.039 13.9 1.8 0.039 13.9 1.8 2.4 1 1 1 2 2 2 0 Short coiled-coil protein DUF5320 PF17253.2 GBG80975.1 - 0.2 12.7 0.1 0.2 12.7 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5320) SOBP PF15279.6 GBG80975.1 - 0.22 12.1 5.2 0.31 11.6 5.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF262 PF03235.14 GBG80975.1 - 1.8 8.7 7.3 2.5 8.2 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Membr_traf_MHD PF10540.9 GBG80975.1 - 2.9 8.1 6.4 6.2 7.0 6.4 1.6 1 1 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain Adaptin_N PF01602.20 GBG80976.1 - 4e-85 286.4 5.0 4.8e-85 286.1 5.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GBG80976.1 - 1.1e-10 41.8 4.9 5.1e-07 29.9 0.1 3.3 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GBG80976.1 - 6.6e-07 29.6 0.3 0.067 13.6 0.0 4.1 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 GBG80976.1 - 2.8e-06 27.7 0.1 0.77 10.3 0.0 4.4 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 GBG80976.1 - 0.00067 19.7 2.2 1.5 9.3 0.0 5.4 6 0 0 6 6 6 1 HEAT repeat Dopey_N PF04118.14 GBG80976.1 - 0.067 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Dopey, N-terminal DNA_alkylation PF08713.11 GBG80976.1 - 0.19 11.4 0.0 29 4.3 0.0 3.0 3 1 0 3 3 3 0 DNA alkylation repair enzyme ParcG PF10274.9 GBG80976.1 - 0.21 11.7 1.2 14 5.7 0.2 3.1 2 1 1 3 3 3 0 Parkin co-regulated protein API5 PF05918.11 GBG80976.1 - 0.68 8.7 0.0 0.68 8.7 0.0 2.7 4 0 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) Beta_helix PF13229.6 GBG80978.1 - 0.0013 18.6 7.9 0.065 13.1 8.0 2.3 1 1 1 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG80978.1 - 0.25 11.9 36.7 2.9 8.6 0.2 7.7 7 2 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Orthopox_A47 PF06334.11 GBG80979.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A47 protein gag-asp_proteas PF13975.6 GBG80980.1 - 1.1e-06 29.1 0.0 2.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG80980.1 - 1.9e-06 27.7 0.0 3.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80980.1 - 4.6e-06 27.2 0.0 1.4e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG80980.1 - 0.00099 18.9 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease PolC_DP2 PF03833.13 GBG80981.1 - 0.33 8.7 0.0 0.47 8.3 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 RVT_1 PF00078.27 GBG80982.1 - 1.3e-09 38.0 0.0 3.7e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG80982.1 - 1.3e-06 28.2 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG80982.1 - 9.3e-06 26.2 0.0 2.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80982.1 - 0.0011 19.4 0.1 0.0054 17.3 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG80982.1 - 0.014 15.2 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) IQ PF00612.27 GBG80982.1 - 0.038 13.8 0.1 0.14 12.0 0.1 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Dpoe2NT PF12213.8 GBG80983.1 - 1.9 8.8 5.3 1.3e+02 2.9 0.1 3.7 1 1 1 2 2 2 0 DNA polymerases epsilon N terminal RVT_1 PF00078.27 GBG80984.1 - 1.5e-26 93.3 0.0 3.5e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG80984.1 - 3e-23 81.8 0.0 7.2e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80984.1 - 1e-15 57.6 1.6 2.7e-15 56.2 0.5 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG80984.1 - 2e-14 53.8 0.0 7.2e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG80984.1 - 9e-11 42.0 0.0 2.5e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG80984.1 - 9.6e-05 22.2 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG80984.1 - 0.0042 17.3 2.5 0.016 15.5 0.5 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG80984.1 - 0.087 13.1 0.4 0.21 11.8 0.4 1.7 1 0 0 1 1 1 0 H2C2 zinc finger CCSAP PF15748.5 GBG80984.1 - 8.7 6.4 8.8 2.7 8.1 0.3 2.6 2 1 0 2 2 2 0 Centriole, cilia and spindle-associated Retrotrans_gag PF03732.17 GBG80985.1 - 0.0017 18.6 0.1 0.0017 18.6 0.1 3.5 4 1 0 4 4 4 1 Retrotransposon gag protein FAM76 PF16046.5 GBG80985.1 - 0.11 11.8 7.5 0.18 11.1 7.5 1.3 1 0 0 1 1 1 0 FAM76 protein DUF4666 PF15697.5 GBG80985.1 - 2 9.1 5.8 1.6 9.4 3.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) PspB PF06667.12 GBG80985.1 - 4.1 7.5 9.4 15 5.7 0.3 2.7 2 0 0 2 2 2 0 Phage shock protein B APG6_N PF17675.1 GBG80985.1 - 7.7 7.1 20.8 14 6.2 1.7 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region COG7 PF10191.9 GBG80986.1 - 2.4e-175 585.0 0.0 1.2e-153 513.2 0.0 2.0 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) DEK_C PF08766.11 GBG80987.1 - 0.0053 16.6 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 DEK C terminal domain Copine PF07002.16 GBG80988.1 - 8.8e-16 58.0 0.0 1.8e-15 57.0 0.0 1.5 1 1 0 1 1 1 1 Copine zf-C3HC4_3 PF13920.6 GBG80988.1 - 0.00018 21.3 6.8 0.00039 20.2 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG80988.1 - 0.0014 18.5 8.8 0.003 17.5 8.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG80988.1 - 0.055 13.3 7.9 0.083 12.8 6.5 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG80988.1 - 0.2 11.5 8.9 0.2 11.5 7.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GBG80988.1 - 0.38 10.6 10.5 0.26 11.2 8.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG80988.1 - 0.61 10.5 8.2 6.1 7.3 8.6 2.3 2 0 0 2 2 2 0 Ring finger domain zf-RING_4 PF14570.6 GBG80988.1 - 1.5 8.7 5.7 3.4 7.5 5.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ATX_III PF08098.11 GBG80988.1 - 8 6.6 8.6 0.43 10.7 2.9 1.9 2 0 0 2 2 2 0 Anemonia sulcata toxin III family RT_RNaseH PF17917.1 GBG80989.1 - 2.8e-28 98.3 0.0 5.7e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG80989.1 - 9e-19 67.4 0.0 3.9e-11 42.9 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG80989.1 - 1.5e-16 60.3 0.8 5.7e-16 58.4 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG80989.1 - 8.6e-13 48.5 0.1 3.2e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG80989.1 - 3.7e-11 42.7 0.0 7.3e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG80989.1 - 2.5e-05 24.4 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG80989.1 - 0.12 12.2 0.1 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase-like RVT_1 PF00078.27 GBG80990.1 - 2.4e-08 33.8 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG80990.1 - 0.0004 21.0 0.0 0.0011 19.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG80990.1 - 0.0019 18.7 0.0 0.0049 17.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG80990.1 - 0.019 15.2 0.0 0.054 13.8 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG80990.1 - 0.4 10.8 1.8 0.76 10.0 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 GBG80991.1 - 6.7e-14 52.1 0.0 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG80991.1 - 1.6e-08 34.5 0.0 3.5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG80991.1 - 0.00012 22.2 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG80991.1 - 0.029 14.2 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain BUD22 PF09073.10 GBG80991.1 - 0.55 9.5 18.6 0.79 9.0 18.6 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG80991.1 - 0.6 8.3 18.9 0.98 7.6 18.9 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG80991.1 - 0.95 8.8 19.3 1.6 8.1 19.3 1.3 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 GBG80991.1 - 6.4 6.8 25.5 13 5.8 25.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 GBG80991.1 - 6.8 4.9 15.6 9.7 4.3 15.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 GBG80991.1 - 9.9 5.5 24.8 17 4.7 24.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Copine PF07002.16 GBG80992.1 - 1.4e-23 83.5 0.0 2.5e-23 82.7 0.0 1.4 1 1 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 GBG80992.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF659 PF04937.15 GBG80993.1 - 3.5e-17 62.7 0.0 5.7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG80993.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region HLH PF00010.26 GBG80994.1 - 0.13 12.3 0.4 0.28 11.2 0.4 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Copine PF07002.16 GBG80995.1 - 5.5e-20 71.8 0.0 7.3e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Copine zf-C3HC4_3 PF13920.6 GBG80995.1 - 7.7e-09 35.3 6.3 1.5e-08 34.4 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG80995.1 - 0.00023 21.0 9.5 0.00023 21.0 9.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG80995.1 - 0.00047 20.0 6.4 0.0011 18.8 6.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GBG80995.1 - 0.0014 18.9 8.9 0.0014 18.9 8.9 2.1 2 0 0 2 2 2 1 Ring finger domain Prenyltrans PF00432.21 GBG80995.1 - 0.0031 17.2 0.2 0.43 10.4 0.1 2.6 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat zf-C3HC4_2 PF13923.6 GBG80995.1 - 0.0087 15.9 9.6 0.022 14.6 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.12 GBG80995.1 - 0.022 14.8 0.8 0.04 14.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) zf-RING_5 PF14634.6 GBG80995.1 - 0.094 12.7 9.0 0.23 11.5 9.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C2H2_9 PF16293.5 GBG80995.1 - 0.3 10.9 1.7 0.44 10.4 0.1 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-RING_4 PF14570.6 GBG80995.1 - 2.7 7.9 9.3 9 6.2 9.3 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GBG80995.1 - 3.3 8.0 7.9 7.2 6.9 7.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 GBG80995.1 - 4.1 7.2 8.7 8.3 6.3 8.7 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Integrase_H2C2 PF17921.1 GBG80996.1 - 3.9e-08 33.3 0.0 7.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG80997.1 - 1.4e-25 89.3 0.0 2.3e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG80997.1 - 5.9e-23 81.1 0.0 1.1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG80997.1 - 9.1e-11 41.7 0.1 1.4e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTPRCAP PF15713.5 GBG80997.1 - 0.043 14.1 26.7 0.86 9.9 9.1 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RED_C PF07807.11 GBG80997.1 - 0.35 11.3 10.0 2.3 8.7 0.8 2.3 2 0 0 2 2 2 0 RED-like protein C-terminal region CDC45 PF02724.14 GBG80997.1 - 1 7.6 18.4 1.1 7.5 4.6 2.1 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 GBG80997.1 - 2.7 7.3 23.4 1.4 8.2 5.4 2.1 2 0 0 2 2 2 0 SDA1 Copine PF07002.16 GBG80998.1 - 1.2e-21 77.2 0.0 1.6e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Copine zf-C3HC4_3 PF13920.6 GBG80998.1 - 1.5e-08 34.4 6.1 2.9e-08 33.4 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG80998.1 - 0.00035 20.4 9.0 0.00035 20.4 9.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG80998.1 - 0.0008 19.2 6.3 0.002 17.9 6.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GBG80998.1 - 0.0013 19.0 8.5 0.0013 19.0 8.5 2.1 2 0 0 2 2 2 1 Ring finger domain Prenyltrans PF00432.21 GBG80998.1 - 0.0061 16.3 0.3 0.42 10.4 0.1 2.6 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat zf-C3HC4_2 PF13923.6 GBG80998.1 - 0.011 15.6 9.2 0.026 14.4 9.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.12 GBG80998.1 - 0.017 15.2 0.4 0.032 14.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) zf-RING_5 PF14634.6 GBG80998.1 - 0.058 13.4 8.7 0.15 12.1 8.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C2H2_9 PF16293.5 GBG80998.1 - 0.28 11.0 1.7 0.44 10.4 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-MIZ PF02891.20 GBG80998.1 - 2.4 8.0 8.8 5.1 6.9 8.8 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.6 GBG80998.1 - 2.6 7.9 9.3 8.7 6.2 9.3 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GBG80998.1 - 2.7 8.2 7.8 6.6 7.0 7.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING gag-asp_proteas PF13975.6 GBG80999.1 - 2.3e-07 31.3 0.3 3.2e-06 27.6 0.0 2.6 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG80999.1 - 3.2e-07 30.9 0.0 2.2e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG80999.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DNA_pol_phi PF04931.13 GBG80999.1 - 8.5 4.3 8.5 13 3.8 8.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Copine PF07002.16 GBG81000.1 - 3.3e-24 85.5 0.0 4.1e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 GBG81000.1 - 0.0099 16.0 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Copine PF07002.16 GBG81001.1 - 7.6e-20 71.3 0.0 1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Copine zf-C3HC4_3 PF13920.6 GBG81001.1 - 2.7e-09 36.7 6.0 5e-09 35.9 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG81001.1 - 5.4e-05 23.0 9.2 0.00014 21.7 9.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG81001.1 - 0.00025 21.3 8.7 0.00025 21.3 8.7 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 GBG81001.1 - 0.00026 20.8 6.3 0.00057 19.7 6.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GBG81001.1 - 0.0038 17.0 8.8 0.0096 15.7 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG81001.1 - 0.0091 15.9 8.9 0.021 14.8 8.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prenyltrans PF00432.21 GBG81001.1 - 0.014 15.1 2.2 1.1 9.0 0.1 3.1 2 1 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat zf-MIZ PF02891.20 GBG81001.1 - 0.44 10.3 8.5 0.83 9.4 8.5 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.6 GBG81001.1 - 1.5 8.7 8.4 4.4 7.2 8.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GBG81001.1 - 1.7 8.8 8.4 3.8 7.7 8.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2235 PF09994.9 GBG81002.1 - 0.092 12.1 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Copine PF07002.16 GBG81003.1 - 3.3e-24 85.5 0.0 4.1e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 GBG81003.1 - 0.0099 16.0 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus zf-CCHC PF00098.23 GBG81005.1 - 1.8e-08 34.1 1.5 3.6e-08 33.1 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG81005.1 - 0.00088 19.0 1.9 0.0019 18.0 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle HTH_32 PF13565.6 GBG81005.1 - 0.0012 19.4 0.1 3.1 8.5 0.1 2.7 2 0 0 2 2 2 2 Homeodomain-like domain gag-asp_proteas PF13975.6 GBG81005.1 - 0.0024 18.4 0.0 0.0058 17.2 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81005.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81005.1 - 0.14 12.8 0.0 0.4 11.4 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG81006.1 - 4.2e-05 23.2 0.1 9.4e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Alpha-amylase PF00128.24 GBG81007.1 - 2.6e-19 70.0 0.2 3.7e-14 53.0 0.0 3.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 GBG81007.1 - 2.1e-09 37.7 0.1 4.7e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 GBG81007.1 - 4e-08 33.5 0.0 1.1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Malt_amylase_C PF16657.5 GBG81007.1 - 0.019 15.1 0.0 0.06 13.5 0.0 1.9 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 GBG81007.1 - 0.18 10.8 0.1 2.9 6.9 0.0 2.2 2 1 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain zf-RING_2 PF13639.6 GBG81008.1 - 3.7e-07 30.4 7.4 3.7e-07 30.4 7.4 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 GBG81008.1 - 1.7e-05 24.6 6.4 1.7e-05 24.6 6.4 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG81008.1 - 2e-05 24.2 2.1 2e-05 24.2 2.1 2.2 2 0 0 2 2 2 1 RING-like zinc finger ubiquitin PF00240.23 GBG81008.1 - 3e-05 23.7 0.1 0.00041 20.0 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin family zf-C3HC4_2 PF13923.6 GBG81008.1 - 4.3e-05 23.3 11.4 0.00016 21.4 6.9 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GBG81008.1 - 0.0016 18.6 4.5 0.0016 18.6 4.5 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 GBG81008.1 - 0.0035 17.3 4.4 0.0035 17.3 4.4 3.2 4 0 0 4 4 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 GBG81008.1 - 0.0049 17.1 9.0 0.0049 17.1 9.0 3.5 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GBG81008.1 - 0.019 14.9 6.2 0.019 14.9 6.2 2.9 3 1 0 3 3 3 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG81008.1 - 0.035 14.0 15.3 0.19 11.6 7.5 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GBG81008.1 - 0.073 12.9 12.9 0.26 11.2 6.4 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 GBG81008.1 - 0.25 11.2 2.6 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 GBG81008.1 - 0.63 10.1 13.3 0.037 14.1 4.3 3.1 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 GBG81008.1 - 1.5 9.0 7.9 4.3 7.6 7.1 2.2 1 1 1 2 2 2 0 RING-variant domain ubiquitin PF00240.23 GBG81009.1 - 4.5e-06 26.3 0.1 0.00013 21.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family PAN_4 PF14295.6 GBG81010.1 - 0.00087 19.2 3.2 0.00087 19.2 3.2 2.0 1 1 1 2 2 2 1 PAN domain Peptidase_S8 PF00082.22 GBG81010.1 - 0.2 10.9 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Subtilase family F-box-like PF12937.7 GBG81011.1 - 2.8e-06 27.1 0.1 1.1e-05 25.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG81011.1 - 8.3e-06 25.5 0.4 3.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 GBG81011.1 - 0.0029 17.2 0.1 0.0071 15.9 0.1 1.7 1 0 0 1 1 1 1 F-box LRR_4 PF12799.7 GBG81011.1 - 0.81 10.2 5.1 3.5 8.2 0.2 3.8 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) rve PF00665.26 GBG81013.1 - 1.4e-15 57.5 0.2 2.8e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81013.1 - 2e-07 31.5 0.0 8.2e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81013.1 - 1.7e-05 25.4 0.0 4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG81013.1 - 0.0037 17.1 0.1 0.011 15.5 0.1 1.8 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81013.1 - 0.0066 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG81013.1 - 0.009 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) PUF PF00806.19 GBG81013.1 - 0.11 12.3 0.0 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat CENP-F_leu_zip PF10473.9 GBG81013.1 - 0.21 11.6 0.1 27 4.8 0.0 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myb_DNA-bind_4 PF13837.6 GBG81014.1 - 2.1e-05 24.8 1.6 3.7e-05 24.0 1.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG81015.1 - 4.1e-28 98.0 0.0 6.7e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81015.1 - 2.1e-14 53.6 0.0 3.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81015.1 - 1.8e-06 27.8 0.4 0.00015 21.5 0.4 2.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG81015.1 - 0.12 12.7 0.2 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain F-box PF00646.33 GBG81016.1 - 2.3e-07 30.5 0.0 5.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG81016.1 - 3.4e-07 30.0 1.9 3.7e-07 29.9 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box_5 PF18511.1 GBG81016.1 - 0.0056 16.2 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box PRIMA1 PF16101.5 GBG81016.1 - 0.17 11.9 1.3 0.33 11.0 1.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Abhydrolase_1 PF00561.20 GBG81018.1 - 2.6e-12 47.0 0.1 4.7e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG81018.1 - 1.8e-09 38.5 5.0 1.8e-09 38.5 5.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG81018.1 - 0.00011 21.5 0.3 0.00041 19.7 0.0 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 GBG81018.1 - 0.071 11.8 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Ndr family Peptidase_S9 PF00326.21 GBG81018.1 - 0.17 11.3 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family RVT_1 PF00078.27 GBG81019.1 - 4.5e-33 114.6 0.1 7.3e-33 113.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81019.1 - 5.4e-18 64.9 0.0 3.3e-17 62.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81019.1 - 1.8e-07 31.4 0.0 5.5e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4392 PF14336.6 GBG81019.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Casc1_N PF15927.5 GBG81019.1 - 0.19 11.4 6.7 0.5 10.0 6.7 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF4219 PF13961.6 GBG81019.1 - 0.88 9.3 3.7 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) FoP_duplication PF13865.6 GBG81019.1 - 9.6 6.8 9.8 29 5.3 9.8 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RT_RNaseH_2 PF17919.1 GBG81021.1 - 1.8e-35 121.0 0.0 2.3e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81021.1 - 4.8e-33 113.6 0.0 7.5e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81022.1 - 4.8e-28 97.1 0.0 8e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81022.1 - 4.6e-26 91.2 0.0 7.4e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81022.1 - 1.2e-13 51.1 0.1 1.8e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG81022.1 - 0.021 14.7 0.0 0.36 10.7 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) SDA1 PF05285.12 GBG81022.1 - 1.4 8.2 21.4 2 7.8 21.4 1.1 1 0 0 1 1 1 0 SDA1 Hrs_helical PF12210.8 GBG81023.1 - 0.0026 18.3 10.4 0.064 13.8 2.2 2.6 2 0 0 2 2 2 2 Hepatocyte growth factor-regulated tyrosine kinase substrate WD40 PF00400.32 GBG81023.1 - 0.0027 18.5 3.9 0.24 12.3 0.1 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4287 PF14117.6 GBG81023.1 - 0.037 14.2 0.9 3.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) CLZ PF16526.5 GBG81023.1 - 0.062 13.7 13.3 0.49 10.8 2.1 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_18 PF13238.6 GBG81023.1 - 0.099 13.2 0.8 0.41 11.2 0.7 2.0 1 1 0 1 1 1 0 AAA domain Med21 PF11221.8 GBG81023.1 - 0.11 12.7 15.6 0.54 10.5 3.8 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex TetR_C_13 PF16925.5 GBG81023.1 - 0.35 10.8 6.4 0.96 9.4 0.5 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BST2 PF16716.5 GBG81023.1 - 0.39 11.3 11.3 0.51 10.9 2.0 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 HalX PF08663.10 GBG81023.1 - 0.44 10.9 14.2 0.23 11.8 2.2 2.5 2 0 0 2 2 2 0 HalX domain WHEP-TRS PF00458.20 GBG81023.1 - 0.49 10.6 3.5 6.1 7.1 0.4 2.5 2 0 0 2 2 2 0 WHEP-TRS domain CdvA PF18822.1 GBG81023.1 - 0.82 9.5 12.9 2 8.2 3.4 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain tRNA-synt_1e PF01406.19 GBG81023.1 - 2.6 7.3 6.6 4.6 6.5 0.6 2.2 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain ABC_tran_Xtn PF12848.7 GBG81023.1 - 2.9 8.0 16.5 1.5 8.9 3.0 2.4 2 0 0 2 2 2 0 ABC transporter bZIP_2 PF07716.15 GBG81023.1 - 5.8 7.1 18.2 2.2 8.4 3.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper rve PF00665.26 GBG81024.1 - 3.1e-12 46.7 0.1 7.6e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG81024.1 - 0.032 13.9 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) WD40 PF00400.32 GBG81025.1 - 3.1e-08 34.1 8.9 0.012 16.5 0.1 6.1 6 1 0 6 6 6 2 WD domain, G-beta repeat Mito_fiss_reg PF05308.11 GBG81025.1 - 0.0074 16.4 2.7 0.014 15.4 2.7 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator AAA_lid_2 PF17863.1 GBG81025.1 - 5.2 7.0 9.9 5.4 6.9 1.1 3.3 2 1 1 3 3 3 0 AAA lid domain DUF3138 PF11336.8 GBG81026.1 - 1.5 7.3 4.8 2.3 6.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) REV PF00424.18 GBG81026.1 - 2 8.5 6.3 0.89 9.6 0.8 2.7 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) Dapper PF15268.6 GBG81026.1 - 9.7 4.9 19.2 12 4.6 19.2 1.1 1 0 0 1 1 1 0 Dapper DDE_Tnp_4 PF13359.6 GBG81027.1 - 7.9e-26 90.6 0.0 1.2e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81027.1 - 9.4e-11 41.7 0.0 2.5e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81027.1 - 0.00013 21.7 0.1 0.16 11.6 0.1 2.4 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG81027.1 - 0.091 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DSHCT PF08148.12 GBG81027.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain zf-CCHC PF00098.23 GBG81029.1 - 0.1 12.7 0.3 0.2 11.8 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle PIN_12 PF16289.5 GBG81029.1 - 1.5 9.3 9.3 0.46 11.0 5.9 1.9 2 0 0 2 2 2 0 PIN domain DASH_Dad2 PF08654.10 GBG81029.1 - 2.2 8.7 12.0 9 6.8 0.7 3.1 1 1 1 2 2 2 0 DASH complex subunit Dad2 Peptidase_C48 PF02902.19 GBG81031.1 - 1.3e-20 74.2 0.0 2.5e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF963 PF06131.11 GBG81031.1 - 0.088 12.2 4.4 0.21 11.0 4.4 1.6 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) HicB_lk_antitox PF15919.5 GBG81032.1 - 9.2 6.4 8.7 13 5.9 4.2 3.2 1 1 1 3 3 3 0 HicB_like antitoxin of bacterial toxin-antitoxin system CHAT PF12770.7 GBG81034.1 - 8.2e-27 94.4 0.0 1.8e-25 89.9 0.0 2.8 2 1 0 2 2 2 1 CHAT domain NOA36 PF06524.12 GBG81034.1 - 0.23 10.7 8.2 0.033 13.5 3.8 1.7 2 0 0 2 2 2 0 NOA36 protein DDE_Tnp_4 PF13359.6 GBG81035.1 - 4.6e-15 55.6 0.0 8.4e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81035.1 - 3e-06 27.0 0.0 4.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein TetR_C_31 PF17940.1 GBG81036.1 - 0.065 13.4 1.3 0.14 12.4 1.3 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RT_RNaseH_2 PF17919.1 GBG81037.1 - 4.4e-25 87.6 0.0 1.4e-24 86.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81037.1 - 7.2e-25 87.8 0.1 1.4e-24 86.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81037.1 - 1.6e-21 76.5 0.0 5e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81037.1 - 4.1e-19 68.4 0.2 1.2e-18 67.0 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81037.1 - 2.8e-08 34.0 0.0 9.4e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG81037.1 - 7.5e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81037.1 - 9.9e-06 26.1 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81037.1 - 1.1e-05 25.9 0.0 2.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG81037.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG81037.1 - 0.0024 18.1 0.0 0.0077 16.4 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG81037.1 - 0.03 14.2 0.2 0.17 11.8 0.0 2.4 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Tweety PF04906.13 GBG81037.1 - 0.18 10.5 1.2 0.35 9.5 1.2 1.4 1 0 0 1 1 1 0 Tweety Retrotrans_gag PF03732.17 GBG81037.1 - 0.31 11.4 6.5 0.28 11.5 0.7 3.2 3 0 0 3 3 3 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG81038.1 - 4.3e-22 78.7 0.0 8.2e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG81038.1 - 2e-20 73.3 0.0 5.1e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG81038.1 - 2.9e-17 62.8 0.0 5.6e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Lectin_N PF03954.14 GBG81038.1 - 0.08 12.7 3.4 0.21 11.3 3.4 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain LMBR1 PF04791.16 GBG81038.1 - 0.6 9.0 5.8 1 8.2 5.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3584 PF12128.8 GBG81038.1 - 1.1 6.7 26.6 1.7 6.1 26.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lys-AminoMut_A PF09043.11 GBG81038.1 - 2 6.7 12.2 0.062 11.8 0.4 2.2 2 0 0 2 2 2 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit DUF659 PF04937.15 GBG81039.1 - 4.2e-19 68.9 0.0 6.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG81040.1 - 6.4e-05 23.3 0.8 0.00012 22.4 0.8 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG81040.1 - 0.08 13.3 0.9 0.19 12.1 0.9 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like BUD22 PF09073.10 GBG81046.1 - 0.39 10.0 18.1 0.48 9.7 18.1 1.1 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 GBG81046.1 - 0.58 9.2 9.7 0.82 8.8 9.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 GBG81046.1 - 0.98 7.6 18.3 1.2 7.2 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG81046.1 - 2.8 7.3 17.2 3.6 6.9 17.2 1.1 1 0 0 1 1 1 0 SDA1 DUF572 PF04502.13 GBG81047.1 - 1.1 8.8 9.7 1.9 8.0 9.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RVT_1 PF00078.27 GBG81048.1 - 2.9e-26 92.3 0.0 5.7e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81048.1 - 1.1e-23 83.1 0.0 2.1e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81048.1 - 9.8e-22 77.2 0.0 1.7e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG81048.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4360 PF14273.6 GBG81049.1 - 1e-38 133.0 1.3 1.2e-38 132.8 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Retrotrans_gag PF03732.17 GBG81050.1 - 8.8 6.7 8.1 5.8 7.3 0.0 3.6 4 1 0 4 4 4 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG81051.1 - 2.9e-05 24.5 0.1 9.3e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF659 PF04937.15 GBG81051.1 - 0.0013 18.6 0.1 0.0035 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Asp_protease_2 PF13650.6 GBG81051.1 - 0.0022 18.6 0.0 0.0066 17.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease TFIIA PF03153.13 GBG81051.1 - 3.7 7.5 8.8 7.8 6.4 8.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF659 PF04937.15 GBG81052.1 - 1.4e-20 73.7 0.1 2.4e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81052.1 - 0.032 14.0 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region S-antigen PF05756.11 GBG81052.1 - 1.3 9.4 3.1 3.6 8.0 3.1 1.7 1 0 0 1 1 1 0 S-antigen protein DUF4360 PF14273.6 GBG81053.1 - 8.4e-43 146.3 0.1 9.6e-43 146.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG81056.1 - 4.8e-31 106.7 0.0 2.4e-15 56.4 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81056.1 - 9.5e-28 97.2 0.1 1.5e-27 96.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81056.1 - 4.7e-24 84.7 0.0 1.3e-23 83.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG81056.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF4360 PF14273.6 GBG81057.1 - 2e-33 115.7 1.9 2.6e-33 115.4 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Integrase_H2C2 PF17921.1 GBG81058.1 - 4e-12 46.1 0.6 8.8e-12 45.0 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG81058.1 - 7e-10 38.8 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81058.1 - 1.9e-06 28.0 0.0 4.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81058.1 - 0.0015 18.7 0.1 0.0036 17.5 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF4360 PF14273.6 GBG81059.1 - 6e-39 133.7 0.1 6.9e-39 133.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81060.1 - 1.1e-38 132.8 0.9 1.3e-38 132.6 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81062.1 - 6e-39 133.7 1.1 6.8e-39 133.6 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Integrase_H2C2 PF17921.1 GBG81063.1 - 5e-15 55.4 0.4 1.2e-14 54.1 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81063.1 - 6.5e-08 32.8 0.0 2.2e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81063.1 - 0.0011 19.5 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG81063.1 - 0.0023 18.1 0.0 0.0062 16.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG81063.1 - 0.0031 18.1 0.0 0.0075 16.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG81063.1 - 0.01 16.1 0.1 0.031 14.5 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein CDC27 PF09507.10 GBG81063.1 - 7 5.9 10.3 18 4.6 10.3 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 gag-asp_proteas PF13975.6 GBG81064.1 - 4.5e-08 33.6 1.5 2.1e-07 31.4 0.0 2.8 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81064.1 - 1.3e-05 25.7 0.1 6.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG81064.1 - 0.0059 16.9 0.0 0.02 15.2 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81064.1 - 0.0065 16.3 0.4 0.015 15.1 0.4 1.6 1 0 0 1 1 1 1 Aspartyl protease TFIIA PF03153.13 GBG81064.1 - 0.92 9.4 7.2 0.84 9.6 1.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Integrase_H2C2 PF17921.1 GBG81065.1 - 1e-15 57.6 0.1 2.3e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81065.1 - 6.2e-14 52.2 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81065.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DUF4360 PF14273.6 GBG81066.1 - 1.4e-42 145.6 0.1 1.6e-42 145.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Myb_DNA-bind_4 PF13837.6 GBG81068.1 - 0.00017 21.9 16.9 0.0057 17.0 3.6 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Peptidase_S37 PF05576.11 GBG81068.1 - 0.00028 19.7 0.0 0.26 9.9 0.0 2.1 2 0 0 2 2 2 2 PS-10 peptidase S37 DUF4360 PF14273.6 GBG81069.1 - 8.3e-39 133.3 0.3 9.5e-39 133.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81070.1 - 5.9e-43 146.8 0.0 6.7e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81071.1 - 3.2e-36 124.9 0.0 4.3e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Myb_DNA-bind_4 PF13837.6 GBG81072.1 - 1.1e-06 28.9 0.3 2e-05 24.9 0.4 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG81072.1 - 0.013 15.6 1.5 0.013 15.6 1.5 2.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG81073.1 - 1.6e-09 38.0 0.8 2.6e-09 37.3 0.8 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG81075.1 - 1.1e-19 70.3 0.0 2.7e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81075.1 - 1.9e-16 60.2 0.0 4.4e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81075.1 - 1.3e-07 31.4 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG81075.1 - 1.4e-06 28.7 0.0 3.4e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81075.1 - 0.0032 18.1 0.0 0.0084 16.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease TRAP_alpha PF03896.16 GBG81077.1 - 0.0016 17.7 1.2 0.0019 17.4 1.2 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SARAF PF06682.12 GBG81077.1 - 0.025 14.2 0.0 0.028 14.1 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SpoIIIAH PF12685.7 GBG81077.1 - 0.088 12.6 2.3 0.11 12.3 2.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein PPP4R2 PF09184.11 GBG81077.1 - 0.27 10.8 7.3 0.3 10.6 7.3 1.1 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 GBG81077.1 - 0.28 9.7 7.2 0.29 9.6 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GBG81077.1 - 0.55 8.3 19.6 0.61 8.1 19.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 GBG81077.1 - 0.6 9.8 4.6 0.8 9.4 4.6 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH BAF1_ABF1 PF04684.13 GBG81077.1 - 1.6 7.7 5.3 1.8 7.5 5.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nop14 PF04147.12 GBG81077.1 - 1.8 6.7 12.2 2 6.5 12.2 1.0 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 GBG81077.1 - 3.9 6.6 10.9 4.4 6.4 10.9 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 GBG81077.1 - 6.2 5.0 7.9 7.3 4.8 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.9 GBG81077.1 - 6.7 6.7 17.2 7.9 6.4 17.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4360 PF14273.6 GBG81078.1 - 6.3e-42 143.5 0.0 7.2e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81079.1 - 2.3e-39 135.1 0.9 2.6e-39 134.9 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF674 PF05056.12 GBG81080.1 - 3.4e-16 59.2 0.6 1.4e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF674) DUF674 PF05056.12 GBG81081.1 - 1.1e-15 57.5 1.1 1.3e-15 57.3 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF674) Integrase_H2C2 PF17921.1 GBG81082.1 - 1.1e-16 60.7 0.0 9.5e-16 57.7 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81082.1 - 4.4e-13 49.5 0.0 1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81082.1 - 1.4e-05 25.2 0.0 3.7e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG81082.1 - 0.00031 20.3 0.1 0.00051 19.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP70 PF00012.20 GBG81084.1 - 1.5e-176 588.2 0.0 1.8e-176 587.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG81084.1 - 9.2e-12 44.4 0.2 6.5e-11 41.6 0.1 2.2 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GBG81084.1 - 0.00042 20.7 0.8 0.2 12.1 0.0 3.0 3 0 0 3 3 3 2 Cell division protein FtsA RAP80_UIM PF18282.1 GBG81084.1 - 0.039 13.7 0.1 0.095 12.5 0.1 1.6 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif EutA PF06277.11 GBG81084.1 - 0.051 12.4 0.1 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA DDR PF08841.10 GBG81084.1 - 0.16 10.9 1.7 1.5 7.7 0.1 2.8 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain zf-CCHC PF00098.23 GBG81085.1 - 8.5e-07 28.8 0.6 1.9e-06 27.7 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG81085.1 - 0.0025 17.6 0.7 0.0049 16.7 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle AP1AR PF15745.5 GBG81085.1 - 0.011 15.4 17.3 0.017 14.8 17.3 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein HAUS-augmin3 PF14932.6 GBG81085.1 - 0.21 11.1 10.5 0.29 10.7 10.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Pirin PF02678.16 GBG81086.1 - 1.8e-30 105.1 0.3 4.2e-30 103.9 0.1 1.7 2 0 0 2 2 2 1 Pirin Pirin_C_2 PF17954.1 GBG81086.1 - 3.9e-13 49.4 0.0 6.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 GBG81086.1 - 2.7e-07 30.2 0.2 6.8e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Cupin domain Pirin_C PF05726.13 GBG81086.1 - 0.00039 20.7 0.0 0.006 16.9 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain DUF2647 PF10839.8 GBG81086.1 - 0.06 13.4 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) Pirin PF02678.16 GBG81087.1 - 1.2e-30 105.7 0.4 2.9e-30 104.4 0.1 1.7 2 0 0 2 2 2 1 Pirin Pirin_C_2 PF17954.1 GBG81087.1 - 2.7e-13 49.9 0.0 4.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 GBG81087.1 - 1.6e-07 31.0 0.2 5e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Cupin domain Pirin_C PF05726.13 GBG81087.1 - 0.00022 21.5 0.0 0.0044 17.3 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain DUF2647 PF10839.8 GBG81087.1 - 0.041 14.0 0.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) HSP70 PF00012.20 GBG81089.1 - 6.9e-179 595.9 0.0 8.2e-179 595.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG81089.1 - 3.4e-11 42.6 0.1 2.5e-09 36.4 0.0 2.9 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.6 GBG81089.1 - 0.0024 18.3 0.3 4.8 7.7 0.0 3.0 3 0 0 3 3 3 2 Cell division protein FtsA EutA PF06277.11 GBG81089.1 - 0.034 13.0 0.1 0.078 11.8 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA MLTR_LBD PF17765.1 GBG81089.1 - 0.089 12.9 1.6 0.19 11.8 1.6 1.5 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain RNase_PH_C PF03725.15 GBG81089.1 - 0.44 10.6 1.9 37 4.4 0.1 3.5 3 0 0 3 3 3 0 3' exoribonuclease family, domain 2 Integrase_H2C2 PF17921.1 GBG81090.1 - 6.1e-16 58.3 0.2 1.5e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG81090.1 - 2e-08 34.7 0.1 7.1e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG81090.1 - 3.1e-07 30.6 0.0 6.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG81090.1 - 1.7e-05 25.3 0.0 5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG81090.1 - 0.0023 17.7 1.6 0.0044 16.8 1.6 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG81090.1 - 0.0035 17.5 0.0 0.0096 16.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVP PF00077.20 GBG81090.1 - 0.013 15.8 0.0 0.042 14.2 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease CK2S PF15011.6 GBG81090.1 - 0.021 14.7 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 Casein Kinase 2 substrate gag-asp_proteas PF13975.6 GBG81091.1 - 4.8e-08 33.5 0.0 1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81091.1 - 0.00046 20.8 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG81091.1 - 0.0016 18.2 0.4 0.0029 17.4 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG81091.1 - 0.0068 16.7 0.0 0.019 15.2 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG81091.1 - 0.051 13.9 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein SICA_C PF12879.7 GBG81091.1 - 0.29 11.1 2.6 1.5 8.8 2.5 2.1 1 1 0 1 1 1 0 SICA C-terminal inner membrane domain Cytochrom_C_2 PF01322.20 GBG81091.1 - 0.87 10.5 4.1 2 9.3 0.2 2.9 3 0 0 3 3 3 0 Cytochrome C' HSP70 PF00012.20 GBG81093.1 - 1.9e-151 505.3 0.0 5.5e-151 503.7 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG81093.1 - 4.1e-10 39.0 0.1 8.3e-05 21.5 0.0 3.2 3 1 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 GBG81093.1 - 0.037 14.4 0.5 16 6.0 0.0 3.8 3 2 0 3 3 3 0 Cell division protein FtsA TetR_C_25 PF17933.1 GBG81093.1 - 0.16 12.3 0.0 21 5.5 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain StbA PF06406.11 GBG81093.1 - 0.21 10.8 0.1 0.68 9.1 0.0 1.7 2 0 0 2 2 2 0 StbA protein HSP70 PF00012.20 GBG81096.1 - 1.9e-156 521.7 0.0 3.2e-156 521.0 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG81096.1 - 8.5e-08 31.4 0.7 0.048 12.5 0.0 3.9 2 1 1 3 3 3 3 MreB/Mbl protein StbA PF06406.11 GBG81096.1 - 0.0064 15.8 0.0 0.012 14.8 0.0 1.4 1 1 0 1 1 1 1 StbA protein FGGY_C PF02782.16 GBG81096.1 - 0.021 14.5 0.0 0.077 12.7 0.0 1.9 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BNR_4 PF15892.5 GBG81096.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-containing family member DUF2457 PF10446.9 GBG81097.1 - 0.0058 15.8 12.3 0.008 15.4 12.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Toxin_4 PF00706.17 GBG81097.1 - 0.061 13.8 0.6 0.1 13.0 0.6 1.3 1 0 0 1 1 1 0 Anenome neurotoxin SAPS PF04499.15 GBG81097.1 - 0.38 9.5 2.8 0.4 9.4 2.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2722 PF10846.8 GBG81097.1 - 0.41 9.6 5.9 0.76 8.6 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.12 GBG81097.1 - 0.56 9.6 20.4 0.64 9.4 20.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG81097.1 - 0.59 8.4 13.3 0.69 8.1 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG81097.1 - 0.86 7.7 18.4 0.96 7.6 18.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG81097.1 - 1 8.6 16.5 1.3 8.3 16.5 1.1 1 0 0 1 1 1 0 BUD22 Smg4_UPF3 PF03467.15 GBG81097.1 - 1.1 9.2 6.2 1.6 8.7 6.2 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family Presenilin PF01080.17 GBG81097.1 - 2.7 6.7 7.0 3.2 6.4 7.0 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GBG81097.1 - 3.8 6.6 5.4 4.5 6.4 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.12 GBG81097.1 - 5.6 6.3 22.3 8.3 5.7 22.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PTPRCAP PF15713.5 GBG81097.1 - 6.7 7.0 22.7 13 6.1 22.7 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PPP4R2 PF09184.11 GBG81097.1 - 8.5 5.9 18.4 13 5.2 18.4 1.3 1 0 0 1 1 1 0 PPP4R2 Hid1 PF12722.7 GBG81097.1 - 9.4 4.2 6.6 10 4.1 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TIM PF00121.18 GBG81099.1 - 1.9e-19 70.0 0.0 2.9e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase HSP70 PF00012.20 GBG81099.1 - 1.2e-06 27.1 0.0 1.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein HCV_NS5a PF01506.19 GBG81099.1 - 0.14 12.1 0.4 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor HSP70 PF00012.20 GBG81100.1 - 5.7e-138 460.7 0.0 6.9e-138 460.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG81100.1 - 4.7e-09 35.5 0.0 1.1e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GBG81100.1 - 0.0019 18.6 0.0 1.3 9.5 0.0 2.5 2 1 0 2 2 2 2 Cell division protein FtsA StbA PF06406.11 GBG81100.1 - 0.054 12.7 0.1 0.13 11.4 0.1 1.6 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.16 GBG81100.1 - 0.12 12.1 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain AAA_9 PF12781.7 GBG81100.1 - 0.23 10.6 0.9 0.56 9.3 0.2 1.8 2 0 0 2 2 2 0 ATP-binding dynein motor region Topo_Zn_Ribbon PF08272.11 GBG81101.1 - 0.013 15.2 0.3 0.032 13.9 0.3 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Ribosomal_L26 PF16906.5 GBG81102.1 - 6.8e-40 135.4 2.3 9.1e-40 135.0 2.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GBG81102.1 - 2.6e-08 33.5 4.4 8.7e-08 31.9 4.4 1.9 1 0 0 1 1 1 1 KOW motif NlpE PF04170.12 GBG81102.1 - 0.028 15.4 0.1 2.5 9.1 0.1 2.2 2 0 0 2 2 2 0 NlpE N-terminal domain RT_RNaseH_2 PF17919.1 GBG81103.1 - 2.4e-30 104.5 0.0 6e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81103.1 - 5.8e-28 97.2 0.2 1.4e-27 96.0 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81103.1 - 6.8e-18 64.5 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81103.1 - 4.8e-15 55.8 0.0 1.5e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain TPR_1 PF00515.28 GBG81103.1 - 1e-13 50.4 1.4 0.0001 22.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG81103.1 - 6.1e-07 29.1 1.3 1.2 9.4 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG81103.1 - 5.2e-05 23.1 0.7 0.23 11.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG81103.1 - 0.0066 16.6 0.0 0.0066 16.6 0.0 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG81103.1 - 0.0099 16.2 0.3 1.2 9.5 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG81103.1 - 0.23 12.4 8.2 3.8 8.6 0.0 4.3 4 1 1 5 5 4 0 Tetratricopeptide repeat zf-CCHC PF00098.23 GBG81103.1 - 3.9 7.7 4.7 9.6 6.5 4.7 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG81104.1 - 5.5e-32 111.1 0.0 9.2e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG81104.1 - 0.0086 16.7 0.0 0.029 15.0 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG81105.1 - 2.2e-30 105.8 0.1 3.1e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG81105.1 - 2.5e-08 34.4 0.0 5.7e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81105.1 - 3.7e-08 33.9 0.0 1.1e-07 32.3 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG81105.1 - 1.8e-06 27.8 0.0 3.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81105.1 - 7.3e-06 25.8 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_6 PF15288.6 GBG81105.1 - 0.0017 18.2 0.6 0.0055 16.5 0.6 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG81105.1 - 0.04 14.0 3.3 0.081 13.0 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG81105.1 - 0.042 13.6 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle PG_binding_1 PF01471.18 GBG81106.1 - 3.5e-07 30.3 0.1 5e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Toprim_C_rpt PF13368.6 GBG81106.1 - 0.0089 16.0 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Topoisomerase C-terminal repeat RT_RNaseH_2 PF17919.1 GBG81108.1 - 2.6e-27 94.8 0.0 4.8e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81108.1 - 2.1e-25 89.0 0.0 3.9e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81108.1 - 1.2e-11 44.6 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG81108.1 - 0.036 13.9 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) CDC45 PF02724.14 GBG81109.1 - 1.8 6.7 7.7 2.7 6.2 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Retrotrans_gag PF03732.17 GBG81111.1 - 0.00049 20.3 2.2 0.0007 19.8 0.4 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein PHM7_cyt PF14703.6 GBG81111.1 - 0.091 13.0 2.3 0.1 12.8 1.1 1.7 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CENP-F_leu_zip PF10473.9 GBG81112.1 - 2.8e-05 24.2 19.6 0.011 15.7 14.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 GBG81112.1 - 0.0015 17.5 13.9 0.0019 17.1 13.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 GBG81112.1 - 0.0031 16.3 7.5 0.0034 16.1 7.5 1.0 1 0 0 1 1 1 1 AAA domain TMF_DNA_bd PF12329.8 GBG81112.1 - 0.0039 17.2 3.3 0.0039 17.2 3.3 3.2 1 1 2 3 3 2 2 TATA element modulatory factor 1 DNA binding TACC_C PF05010.14 GBG81112.1 - 0.0059 16.4 3.0 0.0059 16.4 3.0 2.1 1 1 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FliJ PF02050.16 GBG81112.1 - 0.0061 16.8 9.3 0.0094 16.2 8.3 1.8 1 1 0 1 1 1 1 Flagellar FliJ protein ERM PF00769.19 GBG81112.1 - 0.0063 16.4 14.7 0.011 15.5 14.7 1.4 1 1 0 1 1 1 1 Ezrin/radixin/moesin family DUF1664 PF07889.12 GBG81112.1 - 0.0092 16.0 6.4 0.0093 16.0 1.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) MAD PF05557.13 GBG81112.1 - 0.02 13.3 14.8 0.026 12.9 14.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF948 PF06103.11 GBG81112.1 - 0.033 14.5 1.8 0.54 10.5 0.5 2.6 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.11 GBG81112.1 - 0.037 13.9 2.3 0.38 10.6 0.1 2.3 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) KASH_CCD PF14662.6 GBG81112.1 - 0.064 13.1 18.4 0.12 12.2 17.6 1.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 GBG81112.1 - 0.091 12.9 18.7 0.033 14.3 11.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 GBG81112.1 - 0.098 12.1 16.3 0.3 10.5 7.6 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 GBG81112.1 - 0.13 11.8 9.3 0.14 11.7 9.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4618 PF15397.6 GBG81112.1 - 0.21 11.0 11.9 0.42 10.0 9.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) TMF_TATA_bd PF12325.8 GBG81112.1 - 0.26 11.5 18.2 0.59 10.4 0.8 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding XLF PF09302.11 GBG81112.1 - 0.33 11.1 6.9 0.7 10.0 5.5 2.1 1 1 1 2 2 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component HrpB7 PF09486.10 GBG81112.1 - 0.33 11.3 11.6 2.2 8.7 11.6 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Fib_alpha PF08702.10 GBG81112.1 - 0.41 10.8 7.9 0.56 10.4 3.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 GBG81112.1 - 0.41 11.2 8.2 5 7.7 4.6 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 CorA PF01544.18 GBG81112.1 - 0.43 9.8 9.7 1.6 8.0 1.1 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PKcGMP_CC PF16808.5 GBG81112.1 - 0.45 10.4 13.2 0.46 10.4 0.1 3.9 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phage_Mu_Gam PF07352.12 GBG81112.1 - 0.48 10.3 7.0 1.7 8.5 7.0 2.0 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF3552 PF12072.8 GBG81112.1 - 0.48 9.8 14.6 0.44 9.9 13.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) LPP PF04728.13 GBG81112.1 - 0.52 10.7 9.3 7.4 7.0 1.0 4.3 2 2 3 5 5 4 0 Lipoprotein leucine-zipper DUF641 PF04859.12 GBG81112.1 - 0.59 10.5 12.4 2.1 8.7 0.8 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fez1 PF06818.15 GBG81112.1 - 0.63 10.5 17.3 0.021 15.3 6.2 2.0 1 1 1 2 2 2 0 Fez1 MbeD_MobD PF04899.12 GBG81112.1 - 0.87 9.7 9.0 3.1 8.0 0.4 3.2 1 1 2 3 3 3 0 MbeD/MobD like Lebercilin PF15619.6 GBG81112.1 - 0.91 9.2 22.9 0.14 11.8 7.7 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Syntaxin-6_N PF09177.11 GBG81112.1 - 0.91 10.1 8.7 0.9 10.1 1.4 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FAM76 PF16046.5 GBG81112.1 - 1.1 8.6 8.4 1.4 8.2 8.4 1.2 1 0 0 1 1 1 0 FAM76 protein TPR_MLP1_2 PF07926.12 GBG81112.1 - 1.5 8.9 16.0 0.44 10.6 4.1 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein USP8_interact PF08941.10 GBG81112.1 - 1.6 8.5 6.5 0.66 9.8 1.6 2.1 1 1 1 2 2 2 0 USP8 interacting DUF4407 PF14362.6 GBG81112.1 - 3.2 7.0 6.6 9.7 5.4 6.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 GBG81112.1 - 3.8 6.8 12.1 3.5 6.9 5.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 GBG81112.1 - 4.4 6.3 14.1 6.9 5.7 10.4 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 GBG81112.1 - 4.4 8.0 18.0 8 7.1 5.7 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 GBG81112.1 - 6.6 7.3 21.3 5e+03 -2.1 21.3 2.2 1 1 0 1 1 0 0 Apg6 coiled-coil region Lipoprotein_20 PF13942.6 GBG81112.1 - 7.2 6.5 14.3 0.78 9.6 5.4 2.2 1 1 1 2 2 2 0 YfhG lipoprotein Jnk-SapK_ap_N PF09744.9 GBG81112.1 - 7.5 6.8 20.7 6.7 6.9 10.6 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 RVT_1 PF00078.27 GBG81113.1 - 1.7e-37 129.1 0.1 2.6e-37 128.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81113.1 - 4.2e-17 62.0 0.0 2.5e-16 59.5 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81113.1 - 3.5e-08 33.7 0.0 9.3e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG81113.1 - 1.3e-07 31.4 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81113.1 - 1.5e-06 28.8 0.0 3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81113.1 - 0.00014 22.3 0.1 0.00042 20.8 0.1 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG81113.1 - 0.00044 20.1 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG81113.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF4392 PF14336.6 GBG81113.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Retrotrans_gag PF03732.17 GBG81114.1 - 0.0047 17.2 1.0 0.02 15.2 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein TMEM247 PF15444.6 GBG81114.1 - 0.97 9.4 5.2 0.85 9.6 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 247 RVT_1 PF00078.27 GBG81117.1 - 3.6e-23 82.3 0.8 6.1e-23 81.5 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG81117.1 - 6.8e-06 25.9 2.9 1.4e-05 24.9 2.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG81117.1 - 0.00055 20.5 0.0 0.0016 19.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81117.1 - 0.0029 18.1 0.1 0.0079 16.7 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG81117.1 - 0.023 14.5 3.5 0.052 13.4 3.5 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG81120.1 - 2.1e-27 95.1 0.0 3.8e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81120.1 - 1.4e-25 89.6 0.0 2.9e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81120.1 - 2.3e-21 76.3 0.0 4.3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81120.1 - 9.6e-16 58.1 0.0 3.1e-15 56.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG81120.1 - 4.6e-09 36.3 0.4 1.2e-08 34.9 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG81120.1 - 2.1e-05 24.4 3.2 5.8e-05 23.0 3.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 GBG81120.1 - 0.0015 18.7 0.0 0.0049 17.1 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger F-box PF00646.33 GBG81120.1 - 0.0015 18.3 0.1 0.011 15.6 0.1 2.6 1 0 0 1 1 1 1 F-box domain RVP_2 PF08284.11 GBG81120.1 - 0.0037 17.0 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG81120.1 - 0.0093 16.5 0.0 0.022 15.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81120.1 - 0.011 16.3 0.0 0.03 15.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG81120.1 - 0.033 14.0 0.0 0.086 12.6 0.1 1.6 2 0 0 2 2 2 0 Aspartyl protease F-box-like PF12937.7 GBG81120.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like rve_3 PF13683.6 GBG81120.1 - 0.087 12.6 0.0 0.32 10.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_2 PF13696.6 GBG81120.1 - 0.14 12.0 4.7 0.36 10.7 4.7 1.8 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG81121.1 - 9.3e-24 83.7 0.0 1.9e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81121.1 - 6.1e-20 71.1 0.0 1.4e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81121.1 - 2.3e-19 69.3 0.6 9.7e-19 67.2 0.2 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81121.1 - 1.1e-08 35.2 0.0 4.3e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG81121.1 - 0.00086 19.5 0.0 0.0035 17.6 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG81121.1 - 0.032 14.5 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger TEX19 PF15553.6 GBG81122.1 - 0.061 13.3 0.5 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 zf-C2H2_6 PF13912.6 GBG81125.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Med26_M PF15694.5 GBG81129.1 - 0.077 13.0 5.4 0.1 12.6 4.4 1.7 1 1 0 1 1 1 0 Mediator complex subunit 26 middle domain TrkH PF02386.16 GBG81129.1 - 0.087 11.2 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Cation transport protein KapB PF08810.10 GBG81129.1 - 0.11 12.7 0.0 0.11 12.7 0.0 2.5 2 1 0 2 2 2 0 Kinase associated protein B V_ATPase_I PF01496.19 GBG81129.1 - 0.84 7.5 8.1 0.96 7.3 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Asp-B-Hydro_N PF05279.11 GBG81129.1 - 3.6 7.6 11.1 4.8 7.2 11.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CENP-Q PF13094.6 GBG81130.1 - 0.24 11.6 4.4 0.58 10.3 4.4 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit YwqJ-deaminase PF14431.6 GBG81130.1 - 0.25 11.5 2.1 13 6.0 0.0 2.7 2 0 0 2 2 2 0 YwqJ-like deaminase zf-CCHC PF00098.23 GBG81131.1 - 0.00077 19.4 0.5 0.0012 18.9 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle LRR_4 PF12799.7 GBG81132.1 - 8e-08 32.5 8.1 1.7 9.1 0.0 8.2 6 4 2 8 8 8 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG81132.1 - 3.5e-05 23.5 0.0 0.00012 21.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG81132.1 - 0.00021 21.1 0.2 0.0013 18.6 0.1 2.5 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 GBG81132.1 - 0.006 16.5 0.8 83 3.6 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich repeat BUD22 PF09073.10 GBG81132.1 - 1.8 7.8 7.1 2.5 7.4 7.1 1.1 1 0 0 1 1 1 0 BUD22 LRR_2 PF07723.13 GBG81132.1 - 5.9 7.7 10.9 47 4.9 0.0 4.7 3 1 0 3 3 3 0 Leucine Rich Repeat DDE_Tnp_4 PF13359.6 GBG81133.1 - 0.0022 17.7 0.5 0.009 15.7 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease DUF1388 PF07142.12 GBG81134.1 - 0.014 15.3 0.3 0.084 12.8 0.1 2.2 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) Asp_protease_2 PF13650.6 GBG81137.1 - 1.1e-07 32.4 0.0 2.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81137.1 - 8.4e-07 29.5 0.0 2.1e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81137.1 - 1.9e-06 27.7 0.0 4.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG81137.1 - 1.1e-05 25.6 0.0 4.5e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG81137.1 - 0.00019 21.2 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Tetraspanin PF00335.20 GBG81138.1 - 2.4e-10 40.5 0.0 5.4e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 Tetraspanin family RT_RNaseH_2 PF17919.1 GBG81139.1 - 9.8e-32 109.0 0.0 2.4e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81139.1 - 5.4e-30 103.8 0.0 1.5e-29 102.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81139.1 - 3e-27 95.6 0.2 6.3e-27 94.5 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81139.1 - 5e-16 58.6 0.5 1.1e-15 57.4 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81139.1 - 4.7e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain CCDC154 PF15450.6 GBG81139.1 - 0.3 9.6 7.7 0.51 8.8 7.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 DUF4407 PF14362.6 GBG81139.1 - 0.37 10.1 5.6 0.81 9.0 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG81140.1 - 1.6e-25 90.0 0.1 3e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG81140.1 - 1.9e-07 31.6 0.0 7.7e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81140.1 - 2.5e-07 31.2 0.0 7.1e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81140.1 - 1.2e-05 25.1 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81140.1 - 0.00026 20.8 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG81140.1 - 0.0012 19.0 0.3 0.0038 17.4 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG81141.1 - 1.3e-27 96.8 0.0 2.8e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG81141.1 - 0.00034 20.8 5.5 0.00036 20.7 0.0 3.8 3 1 0 3 3 3 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG81141.1 - 0.0093 16.6 2.5 0.0093 16.6 2.5 3.5 4 0 0 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 GBG81141.1 - 0.31 11.5 1.5 0.84 10.1 0.1 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG81142.1 - 6.1e-29 101.1 0.0 1e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81142.1 - 6.8e-26 90.2 0.0 2.1e-25 88.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81142.1 - 4.4e-21 75.1 0.0 1.2e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81142.1 - 1.1e-18 67.0 0.3 3.9e-18 65.3 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81142.1 - 6.1e-10 39.3 0.0 1.7e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81142.1 - 3e-05 24.5 0.0 9.1e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81142.1 - 7.6e-05 23.3 0.0 0.00021 21.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81142.1 - 0.00018 21.3 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81142.1 - 0.00045 20.0 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Use1 PF09753.9 GBG81142.1 - 1.9 8.1 8.5 1.2 8.8 5.6 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF2497 PF10691.9 GBG81142.1 - 3.8 8.0 5.3 1.3 9.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) RVT_1 PF00078.27 GBG81143.1 - 1.2e-34 119.8 0.1 2.6e-34 118.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81143.1 - 1.3e-30 105.3 0.0 3.2e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81143.1 - 5.6e-27 94.1 0.0 1.5e-26 92.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81143.1 - 7.6e-16 58.4 0.0 1.6e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG81143.1 - 6.6e-08 32.4 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81143.1 - 0.00053 20.6 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG81143.1 - 0.0041 16.9 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CCD48 PF15799.5 GBG81143.1 - 0.0046 15.4 2.9 0.0071 14.7 2.9 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 eIF-1a PF01176.19 GBG81143.1 - 0.006 16.4 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Rhamno_transf PF11316.8 GBG81143.1 - 0.038 13.4 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase Herpes_capsid PF06112.11 GBG81143.1 - 0.047 13.8 5.1 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein gag-asp_proteas PF13975.6 GBG81143.1 - 0.052 14.1 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG81143.1 - 0.077 12.8 0.0 0.29 11.0 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain SRP54 PF00448.22 GBG81143.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain HALZ PF02183.18 GBG81143.1 - 0.9 9.8 3.6 0.62 10.3 1.1 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper RT_RNaseH_2 PF17919.1 GBG81144.1 - 9.4e-34 115.5 0.0 1.9e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81144.1 - 1e-26 93.3 0.0 2.4e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81144.1 - 1.2e-21 77.3 0.0 2.2e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81144.1 - 3.9e-17 62.1 0.6 9.5e-17 60.9 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81144.1 - 3.1e-10 40.3 0.0 6.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4360 PF14273.6 GBG81145.1 - 8.6e-37 126.7 0.0 1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF5053 PF16476.5 GBG81147.1 - 0.14 11.8 0.0 0.42 10.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) ETC_C1_NDUFA4 PF04800.12 GBG81148.1 - 9.5e-30 102.7 0.4 1.2e-29 102.3 0.4 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region RVT_1 PF00078.27 GBG81149.1 - 1.4e-32 113.0 0.0 2.4e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81149.1 - 1.7e-22 79.7 0.0 4.1e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81149.1 - 2.5e-13 49.9 0.1 1e-12 47.9 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81149.1 - 4.4e-13 49.4 0.0 1.3e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG81149.1 - 6.7e-13 48.5 0.0 2e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG81150.1 - 4.5e-06 26.9 0.3 7.8e-06 26.2 0.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG81150.1 - 0.058 13.6 0.6 0.27 11.4 0.6 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain RVT_1 PF00078.27 GBG81151.1 - 5.7e-30 104.5 0.0 9.3e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81151.1 - 4.5e-17 61.9 0.0 8.7e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81151.1 - 9.7e-05 22.6 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ribosomal_L34 PF00468.17 GBG81151.1 - 0.15 12.1 0.0 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L34 Ydc2-catalyt PF09159.10 GBG81153.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Ribosomal_60s PF00428.19 GBG81153.1 - 6.6 7.4 14.7 0.7 10.5 9.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 GBG81153.1 - 9.4 6.7 9.1 27 5.2 8.4 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Retrotrans_gag PF03732.17 GBG81154.1 - 0.00011 22.4 0.5 0.00075 19.7 0.0 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG81155.1 - 8.7e-09 35.2 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG81158.1 - 0.007 15.9 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAM_KSR1 PF13543.6 GBG81158.1 - 0.04 14.1 0.1 0.04 14.1 0.1 2.9 3 0 0 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 JmjC PF02373.22 GBG81158.1 - 0.077 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Na_H_Exchanger PF00999.21 GBG81159.1 - 4.8e-41 140.8 50.3 6.3e-41 140.4 50.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 GBG81159.1 - 0.1 13.1 0.0 2.8 8.4 0.0 2.6 2 1 0 2 2 2 0 Universal stress protein family GEMIN8 PF15348.6 GBG81160.1 - 0.0048 17.2 0.0 0.17 12.1 0.0 2.4 1 1 1 2 2 2 1 Gemini of Cajal bodies-associated protein 8 Acetyltransf_3 PF13302.7 GBG81161.1 - 1e-19 71.6 0.7 6.6e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GBG81161.1 - 5.8e-06 26.5 0.1 2.3e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GBG81161.1 - 6.6e-06 26.3 2.9 2.2e-05 24.6 1.6 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GBG81161.1 - 0.00042 20.2 0.0 0.00093 19.1 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 GBG81161.1 - 0.0016 18.1 4.3 0.048 13.3 0.0 2.5 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain BSP_II PF05432.11 GBG81161.1 - 0.0045 16.7 18.8 0.0077 16.0 18.8 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Coilin_N PF15862.5 GBG81161.1 - 0.017 14.9 1.2 0.017 14.9 1.2 2.2 2 0 0 2 2 2 0 Coilin N-terminus SsgA PF04686.12 GBG81161.1 - 0.063 13.3 0.0 9.8 6.3 0.0 3.0 2 1 1 3 3 3 0 Streptomyces sporulation and cell division protein, SsgA DUF4602 PF15375.6 GBG81161.1 - 0.075 13.3 11.3 0.16 12.3 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) BRICHOS PF04089.14 GBG81161.1 - 0.42 10.9 3.5 1.8 8.9 0.0 2.8 2 1 0 2 2 2 0 BRICHOS domain PGA2 PF07543.12 GBG81161.1 - 1.5 8.8 10.7 3.8 7.5 10.7 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 eIF-3c_N PF05470.12 GBG81161.1 - 5.8 5.1 10.6 8.3 4.6 10.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PIEZO PF15917.5 GBG81161.1 - 7.4 6.0 9.0 12 5.3 8.4 1.6 1 1 0 1 1 1 0 Piezo PMSI1 PF15322.6 GBG81161.1 - 9.7 5.5 11.9 19 4.6 11.9 1.5 1 1 0 1 1 1 0 Protein missing in infertile sperm 1, putative DDE_Tnp_4 PF13359.6 GBG81162.1 - 3.2e-29 101.6 0.0 5.3e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81162.1 - 7.1e-17 61.7 0.0 1.1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81162.1 - 1.7e-06 27.8 0.7 0.00011 21.9 0.0 2.7 3 0 0 3 3 3 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG81162.1 - 0.047 14.1 0.4 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Transposase DDE domain T2SSM PF04612.12 GBG81163.1 - 0.14 12.2 2.7 0.17 11.9 0.1 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M LapA_dom PF06305.11 GBG81163.1 - 0.21 11.5 0.5 0.56 10.1 0.5 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MAP17 PF15807.5 GBG81163.1 - 4.5 7.5 4.6 1.9 8.7 0.0 2.6 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Pyr_redox_2 PF07992.14 GBG81164.1 - 2.5e-55 187.8 3.0 4.1e-55 187.1 3.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GBG81164.1 - 1.9e-28 98.9 0.0 4.6e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DEP PF00610.21 GBG81164.1 - 3.3e-21 75.1 0.2 5.9e-21 74.3 0.2 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pyr_redox PF00070.27 GBG81164.1 - 5.6e-18 65.3 4.9 7.2e-16 58.5 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GBG81164.1 - 2.7e-08 33.3 0.5 8.2e-05 21.9 0.6 2.6 2 0 0 2 2 2 2 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 GBG81164.1 - 1.1e-05 24.9 0.7 0.00012 21.5 0.0 2.6 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GBG81164.1 - 0.00012 22.0 0.0 0.00012 22.0 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 GBG81164.1 - 0.001 19.3 4.0 0.16 12.2 2.5 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GBG81164.1 - 0.0062 15.3 5.8 0.18 10.5 3.2 2.7 3 0 0 3 3 3 1 HI0933-like protein TrkA_N PF02254.18 GBG81164.1 - 0.019 15.2 0.1 0.075 13.3 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 GBG81164.1 - 0.022 14.0 5.3 0.048 12.9 0.0 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 GBG81164.1 - 0.046 14.3 0.0 0.16 12.6 0.0 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 GBG81164.1 - 0.051 12.9 6.7 3.8 6.7 2.6 2.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 GBG81164.1 - 0.052 13.1 1.8 5.5 6.5 0.0 2.7 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 GBG81164.1 - 0.083 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.19 GBG81164.1 - 0.39 9.9 2.8 0.49 9.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 GBG81164.1 - 1.1 8.3 15.3 2.2 7.3 7.5 3.1 4 0 0 4 4 4 0 FAD binding domain FAD_oxidored PF12831.7 GBG81164.1 - 1.9 7.7 8.6 4.2 6.6 6.7 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GBG81164.1 - 3.2 6.7 5.6 7 5.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 GBG81164.1 - 4 6.9 10.5 23 4.4 4.6 3.8 4 1 1 5 5 5 0 FAD dependent oxidoreductase GATase_2 PF00310.21 GBG81168.1 - 3e-176 586.3 0.0 4e-176 585.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GBG81168.1 - 8.5e-150 499.0 0.0 2.5e-149 497.4 0.0 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GBG81168.1 - 6.5e-113 376.9 0.0 3.5e-112 374.4 0.0 2.1 3 0 0 3 3 3 1 Glutamate synthase central domain GXGXG PF01493.19 GBG81168.1 - 2.7e-84 281.5 2.8 4.4e-84 280.8 2.8 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 GBG81168.1 - 2.7e-24 85.9 0.1 7.3e-24 84.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 GBG81168.1 - 2.3e-21 75.7 0.1 5.1e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 GBG81168.1 - 3.8e-09 36.6 0.2 1.4e-08 34.9 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GBG81168.1 - 9.1e-07 28.5 0.1 2.1e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 GBG81168.1 - 1.4e-06 28.7 2.3 0.00014 22.4 0.2 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GBG81168.1 - 2.5e-06 27.3 4.2 0.004 16.8 0.4 3.0 3 0 0 3 3 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GBG81168.1 - 3.5e-05 23.3 0.4 6.1e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GBG81168.1 - 7.9e-05 21.5 0.4 7.9e-05 21.5 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 GBG81168.1 - 8.5e-05 21.9 0.7 0.068 12.4 0.1 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GBG81168.1 - 9.8e-05 21.6 0.2 0.00027 20.2 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 GBG81168.1 - 0.0009 18.6 0.2 0.0019 17.5 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 GBG81168.1 - 0.0013 19.1 0.9 0.46 10.9 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 GBG81168.1 - 0.0049 16.0 2.8 0.04 13.0 0.3 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 GBG81168.1 - 0.006 15.9 0.5 0.014 14.6 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FMO-like PF00743.19 GBG81168.1 - 0.0075 14.7 0.1 1.5 7.1 0.0 3.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.21 GBG81168.1 - 0.026 13.8 2.0 1.2 8.3 0.4 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GBG81168.1 - 0.076 12.4 0.4 1.1 8.6 0.0 3.0 4 0 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 GBG81168.1 - 0.14 11.2 0.2 0.34 9.9 0.2 1.7 1 0 0 1 1 1 0 Lycopene cyclase protein PTPRCAP PF15713.5 GBG81169.1 - 0.0046 17.2 5.1 0.0046 17.2 5.1 3.3 2 1 1 3 3 3 1 Protein tyrosine phosphatase receptor type C-associated HSP70 PF00012.20 GBG81170.1 - 4.6e-260 864.0 5.1 5.2e-260 863.8 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG81170.1 - 6.3e-15 54.8 0.4 8.7e-14 51.1 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG81170.1 - 0.019 14.7 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 GBG81170.1 - 0.11 11.8 0.7 0.42 9.8 0.2 2.2 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase Zincin_2 PF10103.9 GBG81170.1 - 0.12 11.6 0.2 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Zincin-like metallopeptidase Ntox15 PF15604.6 GBG81170.1 - 0.26 11.4 6.8 0.56 10.3 6.8 1.5 1 0 0 1 1 1 0 Novel toxin 15 Myb_DNA-bind_4 PF13837.6 GBG81172.1 - 0.00022 21.6 0.3 0.00043 20.6 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG81173.1 - 1.9e-07 30.8 3.3 4.8e-07 29.6 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Snf7 PF03357.21 GBG81175.1 - 9.6e-42 142.5 11.4 9.6e-42 142.5 11.4 1.6 2 0 0 2 2 2 1 Snf7 RVT_1 PF00078.27 GBG81175.1 - 1.5e-31 109.7 0.1 2.4e-31 109.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81175.1 - 2e-15 56.6 0.0 1.2e-14 54.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG81175.1 - 0.00084 19.3 0.6 0.0019 18.1 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH PF17917.1 GBG81175.1 - 0.0045 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SLX9 PF15341.6 GBG81175.1 - 0.11 12.9 2.7 0.4 11.1 2.7 1.9 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Snf7 PF03357.21 GBG81177.1 - 1.9e-20 73.1 11.7 2.1e-20 73.0 11.7 1.0 1 0 0 1 1 1 1 Snf7 CCDC84 PF14968.6 GBG81177.1 - 0.35 10.4 4.4 0.42 10.2 4.4 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 DDE_Tnp_4 PF13359.6 GBG81179.1 - 1.1e-23 83.6 0.0 2.6e-23 82.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81179.1 - 1.2e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein VPS13_C PF16909.5 GBG81180.1 - 1.3e-15 57.6 1.5 1.1e-12 48.1 0.0 2.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 GBG81180.1 - 0.017 15.4 1.1 0.057 13.8 1.1 1.9 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain VPS13_C PF16909.5 GBG81181.1 - 1.2e-15 57.7 1.5 1e-12 48.2 0.0 2.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 GBG81181.1 - 0.017 15.5 1.1 0.055 13.8 1.1 1.9 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain zf-CCHC PF00098.23 GBG81182.1 - 0.0003 20.7 2.0 0.00053 19.9 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle RPN2_C PF18004.1 GBG81182.1 - 0.0095 15.9 4.4 0.013 15.5 4.4 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain zf-CCHC_3 PF13917.6 GBG81182.1 - 0.022 14.7 0.5 0.055 13.4 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle CDC27 PF09507.10 GBG81182.1 - 0.13 11.6 10.0 0.18 11.2 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LRRC37AB_C PF14914.6 GBG81182.1 - 0.25 11.2 2.7 0.37 10.7 2.7 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain NARP1 PF12569.8 GBG81182.1 - 2.3 7.0 8.1 2.9 6.7 8.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ProSAAS PF07259.12 GBG81182.1 - 4.5 7.2 10.8 3.2 7.7 1.7 2.1 1 1 1 2 2 2 0 ProSAAS precursor DUF3464 PF11947.8 GBG81182.1 - 5.1 6.8 9.4 8 6.2 9.4 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Connexin PF00029.19 GBG81182.1 - 7.5 6.2 4.8 10 5.8 4.8 1.1 1 0 0 1 1 1 0 Connexin Cons_hypoth95 PF03602.15 GBG81183.1 - 3.4e-33 114.8 0.0 5.4e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 DDE_Tnp_4 PF13359.6 GBG81184.1 - 5.1e-25 88.0 0.0 1.4e-24 86.6 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81184.1 - 1.5e-13 50.8 0.0 2.7e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81184.1 - 0.0092 15.6 0.0 0.061 13.0 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG81185.1 - 3.4e-25 88.6 0.0 6.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81185.1 - 7.2e-14 51.9 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81185.1 - 0.0033 17.1 0.0 0.031 13.9 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain SpoU_methylase PF00588.19 GBG81186.1 - 3.9e-27 95.2 0.0 7.6e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family Myb_DNA-bind_4 PF13837.6 GBG81186.1 - 2.8e-11 43.6 0.8 8.1e-11 42.2 0.8 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG81186.1 - 0.0014 18.9 0.1 0.0045 17.3 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Cwf_Cwc_15 PF04889.12 GBG81186.1 - 0.26 11.0 5.9 0.54 9.9 5.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myb_DNA-bind_5 PF13873.6 GBG81186.1 - 2 8.6 5.5 0.58 10.3 1.3 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG81187.1 - 2.2e-11 43.9 0.8 6.6e-11 42.4 0.8 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG81187.1 - 0.0011 19.2 0.1 0.0037 17.5 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Cwf_Cwc_15 PF04889.12 GBG81187.1 - 0.2 11.3 5.9 0.44 10.2 5.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myb_DNA-bind_5 PF13873.6 GBG81187.1 - 1.4 9.1 5.5 0.48 10.5 1.3 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain zf-RING_2 PF13639.6 GBG81188.1 - 1.1e-08 35.3 5.2 1.1e-08 35.3 5.2 2.2 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG81188.1 - 1.2e-06 28.5 3.5 1.2e-06 28.5 3.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG81188.1 - 8.2e-06 25.6 3.5 8.2e-06 25.6 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG81188.1 - 0.00016 21.9 4.4 0.00087 19.5 4.4 2.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GBG81188.1 - 0.0019 18.0 3.6 0.0019 18.0 3.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG81188.1 - 0.0019 18.0 5.1 0.0057 16.5 5.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG81188.1 - 0.0064 16.6 1.1 0.0064 16.6 1.1 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GBG81188.1 - 0.012 15.6 2.0 0.036 14.1 2.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 GBG81188.1 - 0.044 13.5 3.1 0.1 12.4 3.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 GBG81188.1 - 0.37 10.8 12.6 0.0073 16.2 4.5 2.5 3 0 0 3 3 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GBG81188.1 - 0.47 10.1 3.6 1.3 8.7 3.6 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GBG81188.1 - 0.82 9.6 5.8 1.2 9.0 4.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 GBG81188.1 - 0.82 9.5 3.6 1.8 8.4 3.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DivIC PF04977.15 GBG81188.1 - 1.8 8.4 5.1 4.4 7.1 5.1 1.5 1 0 0 1 1 1 0 Septum formation initiator RINGv PF12906.7 GBG81188.1 - 6.5 7.0 8.2 16 5.8 8.2 1.7 1 0 0 1 1 1 0 RING-variant domain DUF5010_C PF18099.1 GBG81189.1 - 0.13 12.4 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 DUF5010 C-terminal domain eRF1_1 PF03463.15 GBG81189.1 - 0.16 11.9 0.0 4.9 7.2 0.1 2.2 2 0 0 2 2 2 0 eRF1 domain 1 RT_RNaseH_2 PF17919.1 GBG81190.1 - 6.9e-34 115.9 0.1 1.3e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81190.1 - 5.6e-30 103.7 0.2 1.1e-29 102.8 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81190.1 - 9.9e-28 97.2 0.2 1.6e-27 96.5 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DSPc PF00782.20 GBG81190.1 - 7.2e-19 67.9 0.0 1.9e-17 63.3 0.1 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Integrase_H2C2 PF17921.1 GBG81190.1 - 1.7e-18 66.5 0.8 1.7e-15 56.8 0.1 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG81190.1 - 0.00058 20.0 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81190.1 - 0.15 12.3 2.1 0.23 11.7 0.0 2.4 2 0 0 2 2 2 0 H2C2 zinc finger Y_phosphatase PF00102.27 GBG81190.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TrkH PF02386.16 GBG81192.1 - 4.6e-56 190.3 22.6 1.7e-51 175.2 18.2 3.6 2 1 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.16 GBG81192.1 - 0.34 10.9 3.9 0.25 11.4 0.7 2.5 2 0 0 2 2 2 0 Ion channel Integrase_H2C2 PF17921.1 GBG81193.1 - 1.6e-15 56.9 0.1 3.2e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81193.1 - 7.7e-13 48.7 0.2 7e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG81193.1 - 3e-08 33.5 0.0 5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Amidase PF01425.21 GBG81194.1 - 2.8e-11 43.0 0.0 3e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Amidase fn3_PAP PF17808.1 GBG81195.1 - 5e-21 75.0 1.0 3.2e-20 72.4 1.0 2.2 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Pur_ac_phosph_N PF16656.5 GBG81195.1 - 1.1e-17 64.4 0.4 2.4e-17 63.3 0.4 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 GBG81195.1 - 4.7e-14 53.0 0.0 1.2e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 GBG81195.1 - 2e-13 51.3 0.0 5.3e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C4H2 PF10146.9 GBG81198.1 - 0.034 14.5 8.9 0.066 13.5 8.9 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein DUF812 PF05667.11 GBG81198.1 - 0.057 12.3 21.0 0.075 11.9 21.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 GBG81198.1 - 6.6 6.8 8.1 4 7.5 3.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF659 PF04937.15 GBG81199.1 - 4e-20 72.2 0.0 9.6e-20 71.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG81199.1 - 0.00039 20.0 8.8 0.042 13.7 3.3 2.8 2 0 0 2 2 2 2 AT hook motif zf-HC5HC2H PF13771.6 GBG81200.1 - 0.00049 20.3 3.2 0.0022 18.2 3.2 2.1 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GBG81200.1 - 0.0022 18.1 2.2 0.0055 16.9 2.2 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain Peptidase_S64 PF08192.11 GBG81200.1 - 3.5 6.0 16.2 4.8 5.6 16.2 1.3 1 0 0 1 1 1 0 Peptidase family S64 BUD22 PF09073.10 GBG81201.1 - 0.42 9.9 27.8 0.64 9.3 27.8 1.3 1 0 0 1 1 1 0 BUD22 PRP38_assoc PF12871.7 GBG81201.1 - 3.2 8.4 61.9 0.32 11.6 38.1 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TT_ORF1 PF02956.14 GBG81201.1 - 3.4 6.2 27.7 4.3 5.9 27.7 1.2 1 0 0 1 1 1 0 TT viral orf 1 Rrn6 PF10214.9 GBG81201.1 - 9.9 4.5 18.2 14 4.0 18.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor WSD PF15613.6 GBG81202.1 - 7.8e-22 77.6 0.0 7.8e-22 77.6 0.0 5.6 6 2 0 6 6 6 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 GBG81202.1 - 3e-13 49.5 43.9 1.2e-05 25.1 10.5 3.7 3 0 0 3 3 3 3 PHD-finger zf-HC5HC2H PF13771.6 GBG81202.1 - 1.1e-06 28.8 32.7 0.0044 17.2 4.3 4.3 3 0 0 3 3 3 3 PHD-like zinc-binding domain WHIM1 PF15612.6 GBG81202.1 - 1.1e-06 28.0 0.7 2.6e-06 26.8 0.7 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_2 PF13831.6 GBG81202.1 - 1.1e-05 24.9 30.6 9.2e-05 21.9 1.2 4.1 4 0 0 4 4 4 3 PHD-finger DDT PF02791.17 GBG81202.1 - 5.1e-05 23.5 1.6 0.00027 21.2 0.2 2.4 2 0 0 2 2 2 1 DDT domain zf-HC5HC2H_2 PF13832.6 GBG81202.1 - 0.0062 16.7 2.4 0.0062 16.7 2.4 4.6 4 1 1 5 5 5 2 PHD-zinc-finger like domain Cytochrome_CBB3 PF13442.6 GBG81202.1 - 0.71 10.2 7.0 1.8 9.0 0.1 3.6 3 0 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III WSD PF15613.6 GBG81203.1 - 7.7e-22 77.6 0.0 7.7e-22 77.6 0.0 5.6 6 2 0 6 6 6 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 GBG81203.1 - 2.9e-13 49.5 43.9 1.1e-05 25.2 10.5 3.7 3 0 0 3 3 3 3 PHD-finger zf-HC5HC2H PF13771.6 GBG81203.1 - 4.6e-07 30.0 31.9 0.0044 17.3 4.3 4.3 3 0 0 3 3 3 3 PHD-like zinc-binding domain WHIM1 PF15612.6 GBG81203.1 - 1.1e-06 28.0 0.7 2.6e-06 26.8 0.7 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_2 PF13831.6 GBG81203.1 - 1.1e-05 24.9 30.6 9.2e-05 21.9 1.2 4.1 4 0 0 4 4 4 3 PHD-finger DDT PF02791.17 GBG81203.1 - 5e-05 23.5 1.6 0.00026 21.2 0.2 2.4 2 0 0 2 2 2 1 DDT domain zf-HC5HC2H_2 PF13832.6 GBG81203.1 - 0.0061 16.7 2.4 0.0061 16.7 2.4 4.6 4 1 1 5 5 5 2 PHD-zinc-finger like domain Cytochrome_CBB3 PF13442.6 GBG81203.1 - 0.7 10.3 7.0 1.8 9.0 0.1 3.6 3 0 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III B9-C2 PF07162.11 GBG81204.1 - 3.4e-25 89.2 0.0 4.8e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein PaaX PF07848.12 GBG81204.1 - 0.15 12.3 0.0 18 5.7 0.0 2.3 2 0 0 2 2 2 0 PaaX-like protein Integrase_H2C2 PF17921.1 GBG81206.1 - 2.5e-17 62.7 0.8 4e-17 62.1 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG81206.1 - 5e-15 55.7 0.2 1.6e-14 54.1 0.2 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81206.1 - 4.1e-08 33.2 0.0 1.1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81206.1 - 4.9e-07 30.0 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81206.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 H2C2 zinc finger JSRP PF15312.6 GBG81208.1 - 0.013 15.4 0.1 0.091 12.7 0.0 2.4 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein RT_RNaseH_2 PF17919.1 GBG81209.1 - 6.3e-31 106.4 0.0 1.8e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81209.1 - 1.3e-30 105.7 0.0 3e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81209.1 - 0.00015 21.4 0.1 0.00029 20.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG81209.1 - 0.0061 16.8 4.4 0.0087 16.3 0.0 3.5 4 0 0 4 4 4 1 Retrotransposon gag protein Phage_GPO PF05929.11 GBG81209.1 - 0.098 12.3 0.1 0.098 12.3 0.1 3.5 2 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Enterotoxin_HS1 PF08090.11 GBG81209.1 - 0.13 12.2 2.0 0.33 11.0 2.0 1.6 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 Oxysterol_BP PF01237.18 GBG81210.1 - 2.3e-35 122.1 2.1 1.5e-32 112.9 2.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein GIY-YIG PF01541.24 GBG81211.1 - 3.8e-07 30.3 0.0 3.8e-07 30.3 0.0 2.6 3 1 0 3 3 3 1 GIY-YIG catalytic domain Peptidase_U57 PF05582.12 GBG81211.1 - 0.059 12.6 0.1 0.059 12.6 0.1 2.7 3 0 0 3 3 3 0 YabG peptidase U57 Sigma70_r2 PF04542.14 GBG81211.1 - 0.094 12.5 0.1 0.094 12.5 0.1 2.2 2 0 0 2 2 2 0 Sigma-70 region 2 ASPRs PF17641.2 GBG81211.1 - 0.71 10.2 3.9 0.74 10.1 0.0 2.6 2 0 0 2 2 2 0 Ancylostoma-associated secreted protein related Aldedh PF00171.22 GBG81212.1 - 9.5e-64 215.6 1.6 5.8e-43 147.1 1.4 3.0 1 1 2 3 3 3 3 Aldehyde dehydrogenase family Glyco_hydro_9 PF00759.19 GBG81214.1 - 9.1e-128 427.2 1.9 1e-127 427.0 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 GldM_C PF12080.8 GBG81214.1 - 0.05 13.8 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 GldM C-terminal domain RT_RNaseH_2 PF17919.1 GBG81215.1 - 1.6e-25 89.0 0.0 3.5e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81215.1 - 6.9e-21 74.5 0.0 1.4e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81215.1 - 9.1e-12 45.2 0.0 2.3e-08 34.2 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG81215.1 - 6.9e-11 42.1 0.7 2.8e-07 30.3 0.2 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG81215.1 - 3.9e-07 30.5 0.0 9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81215.1 - 4.2e-07 30.5 0.0 1.3e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81215.1 - 4.9e-07 29.6 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81215.1 - 9.5e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG81215.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain APG17 PF04108.12 GBG81215.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Retrotrans_gag PF03732.17 GBG81215.1 - 0.096 13.0 0.5 0.36 11.1 0.5 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein WES_acyltransf PF03007.16 GBG81215.1 - 0.12 12.1 0.5 0.66 9.7 0.1 2.3 3 0 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain RVT_1 PF00078.27 GBG81216.1 - 5.5e-30 104.5 0.1 8.3e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81216.1 - 9.3e-25 86.6 0.0 1.9e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81216.1 - 1.9e-15 57.0 0.0 3.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG81216.1 - 6.7e-08 33.0 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81216.1 - 1.5e-07 31.9 0.0 3.6e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81216.1 - 3.3e-06 26.9 0.0 9.8e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81216.1 - 1.8e-05 24.5 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease EGF_2 PF07974.13 GBG81217.1 - 0.00043 20.6 7.9 0.00043 20.6 7.9 2.5 2 0 0 2 2 2 1 EGF-like domain Laminin_EGF PF00053.24 GBG81217.1 - 0.0057 16.8 9.6 0.014 15.6 9.6 1.6 1 0 0 1 1 1 1 Laminin EGF domain Golgin_A5 PF09787.9 GBG81218.1 - 0.16 11.4 17.6 0.14 11.6 4.6 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 NINJA_B PF16136.5 GBG81218.1 - 1.2 9.5 9.8 0.23 11.9 3.5 2.2 2 0 0 2 2 2 0 Putative nuclear localisation signal DUF2020 PF09449.10 GBG81219.1 - 1.9 8.3 4.3 4.8 7.0 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) RT_RNaseH_2 PF17919.1 GBG81220.1 - 3.4e-27 94.4 0.0 5.5e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81220.1 - 2.2e-23 82.5 0.0 3.6e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BUD22 PF09073.10 GBG81220.1 - 0.72 9.1 11.2 1 8.6 11.2 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG81220.1 - 2 6.5 11.3 2.6 6.2 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG81220.1 - 6.2 6.1 11.1 8.3 5.7 11.1 1.1 1 0 0 1 1 1 0 SDA1 PHD PF00628.29 GBG81225.1 - 0.00011 22.0 5.7 0.00022 21.0 5.7 1.5 1 0 0 1 1 1 1 PHD-finger Spt20 PF12090.8 GBG81225.1 - 0.07 12.7 8.0 0.21 11.1 8.0 1.8 1 0 0 1 1 1 0 Spt20 family RVT_1 PF00078.27 GBG81227.1 - 1.5e-25 90.0 0.3 6.5e-25 88.0 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG81227.1 - 6e-14 52.2 0.0 1.4e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) FAM76 PF16046.5 GBG81227.1 - 6.4 6.0 8.6 11 5.3 8.6 1.3 1 0 0 1 1 1 0 FAM76 protein DUF737 PF05300.11 GBG81228.1 - 0.036 14.4 2.8 0.049 14.0 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) RVT_1 PF00078.27 GBG81229.1 - 7.7e-28 97.5 0.0 1.4e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81229.1 - 4.1e-26 91.3 0.0 1.2e-25 89.8 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81229.1 - 4.8e-24 84.3 0.0 7.1e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81229.1 - 0.001 19.1 0.1 0.0023 18.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF5320 PF17253.2 GBG81230.1 - 0.055 14.5 0.5 0.055 14.5 0.5 3.3 3 1 1 4 4 4 0 Family of unknown function (DUF5320) PriC PF07445.12 GBG81230.1 - 8.4 6.3 16.2 0.12 12.3 4.7 3.0 3 1 0 3 3 3 0 Primosomal replication protein priC Imm52 PF15579.6 GBG81232.1 - 0.1 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 52 Pex14_N PF04695.13 GBG81233.1 - 0.8 10.3 4.8 0.42 11.3 2.6 1.5 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.14 GBG81233.1 - 3.4 5.8 10.7 4.4 5.5 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH PF17917.1 GBG81234.1 - 1.4e-29 102.4 0.0 4.1e-29 100.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81234.1 - 7.1e-29 99.8 0.0 2.4e-28 98.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81234.1 - 7.1e-12 45.3 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81236.1 - 6.5e-23 81.0 0.1 1.5e-22 79.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81236.1 - 2.7e-22 78.7 0.0 5.6e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81236.1 - 2.2e-17 62.9 0.9 6.9e-17 61.3 0.9 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81236.1 - 7.3e-05 22.9 0.1 0.00018 21.6 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81236.1 - 0.0023 18.1 0.1 0.0077 16.4 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG81236.1 - 0.004 16.7 0.2 0.0085 15.6 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LAP1C PF05609.12 GBG81236.1 - 7.7 5.5 12.6 12 4.9 12.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF659 PF04937.15 GBG81237.1 - 3.8e-09 36.6 0.1 1.9e-06 27.8 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81237.1 - 0.0011 18.7 0.8 0.005 16.6 0.6 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf_C2H2_13 PF18508.1 GBG81237.1 - 0.12 11.9 0.1 0.55 9.9 0.1 2.0 2 0 0 2 2 2 0 Zinc finger domain FlaC_arch PF05377.11 GBG81238.1 - 0.7 10.3 7.2 4 7.9 0.4 4.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) RVT_1 PF00078.27 GBG81241.1 - 2.7e-37 128.5 0.1 4.5e-37 127.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81241.1 - 7e-29 100.2 0.0 1.6e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81241.1 - 1.1e-28 99.1 0.0 3.7e-28 97.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG81242.1 - 0.0012 19.1 3.3 0.0012 19.1 3.3 1.8 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG81242.1 - 0.0053 16.8 2.1 0.012 15.7 2.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RNA_pol_Rpb6 PF01192.22 GBG81243.1 - 1.1e-15 57.2 0.1 1.7e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Trypan_PARP PF05887.11 GBG81243.1 - 7.4 6.6 14.1 6.1 6.8 13.5 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sorting_nexin PF03700.13 GBG81244.1 - 0.0012 19.5 0.6 0.0013 19.3 0.6 1.1 1 0 0 1 1 1 1 Sorting nexin, N-terminal domain ABC_tran PF00005.27 GBG81246.1 - 9.3e-35 120.1 0.0 1.6e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GBG81246.1 - 1.4e-09 38.1 5.6 1.9e-09 37.6 5.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 GBG81246.1 - 3.6e-05 24.2 0.1 6.8e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GBG81246.1 - 0.00022 20.9 0.5 0.00084 19.0 0.3 2.1 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG81246.1 - 0.00026 21.3 0.1 0.0015 18.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 GBG81246.1 - 0.00031 20.9 0.6 0.00067 19.8 0.6 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain Zeta_toxin PF06414.12 GBG81246.1 - 0.0012 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin T2SSE PF00437.20 GBG81246.1 - 0.0024 17.0 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 GBG81246.1 - 0.0029 18.1 0.0 0.0065 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GBG81246.1 - 0.014 14.6 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 GBG81246.1 - 0.017 15.0 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 GBG81246.1 - 0.02 14.4 2.5 1.3 8.4 0.8 2.8 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 GBG81246.1 - 0.026 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 GBG81246.1 - 0.03 13.8 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 GBG81246.1 - 0.033 13.9 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 GBG81246.1 - 0.034 14.2 0.0 0.31 11.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 GBG81246.1 - 0.047 13.6 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase LrgA PF03788.14 GBG81246.1 - 0.048 13.6 5.6 0.14 12.2 5.6 1.8 1 0 0 1 1 1 0 LrgA family AAA_28 PF13521.6 GBG81246.1 - 0.05 13.8 0.8 0.23 11.7 0.8 2.2 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 GBG81246.1 - 0.058 12.7 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 GBG81246.1 - 0.091 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1442 PF07279.11 GBG81246.1 - 0.092 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) AAA_21 PF13304.6 GBG81246.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GBG81246.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 GBG81246.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF447 PF04289.12 GBG81246.1 - 0.16 11.8 0.0 4.9 6.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF447) RT_RNaseH_2 PF17919.1 GBG81247.1 - 2.6e-22 78.7 0.0 5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81247.1 - 1.2e-20 73.8 0.0 3.7e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81247.1 - 0.0015 18.0 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG81247.1 - 0.0029 18.1 0.1 0.0067 17.0 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG81247.1 - 0.0045 16.8 0.5 0.0093 15.8 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG81247.1 - 0.011 16.3 0.1 0.029 15.0 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG81247.1 - 0.043 14.1 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Choline_kin_N PF04428.14 GBG81247.1 - 0.15 11.8 0.1 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Choline kinase N terminus zf-CCHC PF00098.23 GBG81247.1 - 2.4 8.4 5.9 0.26 11.4 1.3 1.9 2 0 0 2 2 2 0 Zinc knuckle Astro_capsid_p PF12226.8 GBG81249.1 - 0.0093 15.2 10.7 0.0093 15.2 10.7 1.6 2 0 0 2 2 2 1 Turkey astrovirus capsid protein Shugoshin_N PF07558.11 GBG81249.1 - 0.12 12.2 1.9 0.17 11.8 0.4 2.1 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region EcsC PF12787.7 GBG81249.1 - 1.2 8.8 12.5 0.019 14.6 5.1 1.7 2 0 0 2 2 2 0 EcsC protein family COMP PF11598.8 GBG81249.1 - 6.7 7.3 5.6 2.8 8.5 0.5 2.5 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein NOA36 PF06524.12 GBG81249.1 - 7.2 5.8 12.0 16 4.7 12.0 1.5 1 0 0 1 1 1 0 NOA36 protein RNA_pol_Rpb2_7 PF04560.20 GBG81250.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 7 DUF1108 PF06531.11 GBG81251.1 - 0.25 11.7 1.2 0.88 9.9 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1108) LTXXQ PF07813.12 GBG81251.1 - 2.2 9.1 18.4 0.16 12.7 6.6 2.6 2 1 1 3 3 3 0 LTXXQ motif family protein RT_RNaseH_2 PF17919.1 GBG81252.1 - 6.9e-31 106.3 0.1 3e-30 104.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81252.1 - 2.7e-30 104.8 0.1 1.4e-29 102.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81252.1 - 7.4e-19 67.6 0.7 2.1e-18 66.2 0.7 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81252.1 - 3e-16 59.7 0.2 1.1e-15 57.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG81252.1 - 0.00018 21.1 0.1 0.00045 19.8 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG81252.1 - 0.0009 19.4 0.1 0.0029 17.8 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG81252.1 - 0.007 16.6 0.0 0.053 13.8 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Phage_GPO PF05929.11 GBG81252.1 - 0.075 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Retrotrans_gag PF03732.17 GBG81253.1 - 3.6e-06 27.2 8.3 0.44 10.9 0.0 4.6 3 1 1 4 4 4 3 Retrotransposon gag protein Lys-AminoMut_A PF09043.11 GBG81253.1 - 0.0022 16.5 0.4 0.0022 16.5 0.4 1.8 2 0 0 2 2 2 1 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit CLZ PF16526.5 GBG81253.1 - 0.24 11.8 3.8 0.53 10.7 0.6 3.0 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RNR_Alpha PF17975.1 GBG81253.1 - 2 9.0 4.3 9 6.9 0.1 3.0 3 0 0 3 3 3 0 Ribonucleotide reductase alpha domain Use1 PF09753.9 GBG81253.1 - 3.4 7.3 15.1 8.1 6.1 15.1 1.6 1 0 0 1 1 1 0 Membrane fusion protein Use1 YPEB PF14620.6 GBG81254.1 - 0.056 12.8 3.6 0.091 12.1 3.6 1.2 1 0 0 1 1 1 0 YpeB sporulation Asp_protease_2 PF13650.6 GBG81255.1 - 1.2e-07 32.2 0.1 2.8e-06 27.9 0.0 2.7 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81255.1 - 2.6e-05 24.7 0.2 7.7e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG81255.1 - 0.00021 21.2 2.6 0.00039 20.4 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG81256.1 - 0.0014 18.2 1.0 0.0063 16.1 0.1 2.5 3 1 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4041 PF13250.6 GBG81256.1 - 0.016 15.1 0.6 8 6.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) CBS PF00571.28 GBG81256.1 - 0.089 13.3 0.0 4.9 7.7 0.0 2.5 2 0 0 2 2 2 0 CBS domain Ribosomal_S4e PF00900.20 GBG81256.1 - 0.12 12.3 0.0 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Ribosomal family S4e PAS_3 PF08447.12 GBG81256.1 - 0.12 12.6 0.1 34 4.8 0.0 3.1 2 0 0 2 2 2 0 PAS fold AAA_11 PF13086.6 GBG81256.1 - 0.2 11.4 7.0 0.36 10.6 7.0 1.5 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.16 GBG81256.1 - 0.72 8.7 1.4 0.97 8.3 1.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein XRN_M PF17846.1 GBG81256.1 - 1.1 8.1 7.1 2 7.2 7.1 1.4 1 0 0 1 1 1 0 Xrn1 helical domain CDC45 PF02724.14 GBG81256.1 - 1.5 7.0 10.9 2.2 6.5 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4481 PF14800.6 GBG81256.1 - 2.4 7.6 4.1 4.3 6.7 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) RR_TM4-6 PF06459.12 GBG81256.1 - 5.8 6.7 15.0 12 5.6 15.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DAG_kinase_N PF14513.6 GBG81256.1 - 6.9 6.8 8.6 31 4.7 4.1 3.2 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus zf-CCHC PF00098.23 GBG81257.1 - 3.2e-07 30.1 2.7 6.8e-07 29.1 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Cupin_8 PF13621.6 GBG81257.1 - 0.17 11.5 1.5 0.23 11.2 1.5 1.1 1 0 0 1 1 1 0 Cupin-like domain GBP_C PF02841.14 GBG81257.1 - 6.2 6.1 18.6 8.9 5.6 18.6 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain GIY-YIG PF01541.24 GBG81258.1 - 7.8e-06 26.1 0.0 4.1e-05 23.8 0.0 2.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain Alanine_zipper PF11839.8 GBG81258.1 - 0.0053 17.1 8.7 0.019 15.3 8.7 1.9 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein DUF659 PF04937.15 GBG81259.1 - 9e-05 22.4 0.0 0.00069 19.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG81260.1 - 0.00083 19.3 2.2 0.0021 18.1 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG81260.1 - 0.0055 16.5 5.0 0.0055 16.5 5.0 1.8 2 0 0 2 2 2 1 Zinc knuckle Toxin_25 PF08095.11 GBG81260.1 - 0.035 14.0 0.1 0.094 12.7 0.1 1.7 1 0 0 1 1 1 0 Hefutoxin family SAP PF02037.27 GBG81260.1 - 0.037 13.8 0.2 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 SAP domain RT_RNaseH_2 PF17919.1 GBG81262.1 - 9.2e-24 83.4 0.0 2.2e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81262.1 - 3.1e-22 78.8 0.0 6.9e-21 74.5 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG81262.1 - 0.002 18.4 0.5 0.018 15.3 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG81262.1 - 0.0089 15.8 1.0 0.014 15.2 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF1664 PF07889.12 GBG81262.1 - 0.12 12.5 0.6 3 7.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-CCHC_6 PF15288.6 GBG81262.1 - 0.18 11.6 0.5 0.44 10.4 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG81262.1 - 0.22 11.6 1.5 0.47 10.6 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG81264.1 - 2e-23 82.3 0.0 6.7e-23 80.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81264.1 - 1.1e-20 73.9 0.0 1.4e-19 70.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81264.1 - 1.7e-12 47.2 0.0 5.1e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81264.1 - 6e-12 45.8 0.0 1.6e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG81264.1 - 0.03 14.1 0.0 0.12 12.1 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain Diphthami_syn_2 PF01902.17 GBG81264.1 - 0.093 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Diphthamide synthase PDGLE PF13190.6 GBG81264.1 - 0.098 12.6 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 PDGLE domain zf-H2C2 PF09337.10 GBG81264.1 - 0.17 12.1 0.1 0.45 10.8 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger GAIN PF16489.5 GBG81265.1 - 0.18 11.2 1.2 0.28 10.6 0.3 1.7 2 0 0 2 2 2 0 GPCR-Autoproteolysis INducing (GAIN) domain DUF730 PF05325.11 GBG81267.1 - 0.02 14.9 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF730) ENTH PF01417.20 GBG81268.1 - 6e-12 45.7 0.0 3.7e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.16 GBG81268.1 - 0.0041 16.1 0.0 0.0089 15.0 0.0 1.5 2 0 0 2 2 2 1 ANTH domain VHS PF00790.19 GBG81268.1 - 0.024 14.5 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 VHS domain YmgB PF10798.8 GBG81268.1 - 0.13 12.1 0.5 0.24 11.2 0.5 1.3 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR MMS19_N PF14500.6 GBG81268.1 - 0.19 11.3 0.0 0.49 9.9 0.0 1.6 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF659 PF04937.15 GBG81270.1 - 2.8e-16 59.8 0.3 4.6e-16 59.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG81270.1 - 0.18 12.0 0.6 26 5.0 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain UPF0561 PF10573.9 GBG81270.1 - 9.3 6.4 13.5 0.51 10.5 0.4 3.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0561 DUF3685 PF12452.8 GBG81271.1 - 3e-15 56.4 2.5 5.2e-13 49.1 1.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3685) DUF1373 PF07117.11 GBG81271.1 - 0.052 13.6 0.3 0.068 13.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) tRNA_int_endo PF01974.17 GBG81272.1 - 3.9e-05 23.6 0.0 8.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PhzC-PhzF PF02567.16 GBG81273.1 - 6.4e-67 226.0 0.0 9.1e-49 166.4 0.0 2.8 2 1 0 2 2 2 2 Phenazine biosynthesis-like protein MRI PF15325.6 GBG81273.1 - 8.5 7.5 8.6 6.1 8.0 1.6 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection HCNGP PF07818.13 GBG81274.1 - 5.3e-26 91.1 0.1 1.3e-25 89.9 0.1 1.6 1 0 0 1 1 1 1 HCNGP-like protein BUD22 PF09073.10 GBG81274.1 - 0.0081 15.5 19.7 0.011 15.1 19.7 1.2 1 0 0 1 1 1 1 BUD22 CDC27 PF09507.10 GBG81274.1 - 1.8 7.8 25.8 3.2 7.0 25.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 WD40 PF00400.32 GBG81275.1 - 0.0043 17.8 0.6 0.46 11.4 0.2 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_3 PF13570.6 GBG81275.1 - 0.017 15.6 2.5 0.75 10.4 0.2 3.3 3 0 0 3 3 3 0 PQQ-like domain Frtz PF11768.8 GBG81275.1 - 0.055 11.8 0.0 0.092 11.0 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz MutS_V PF00488.21 GBG81276.1 - 7.4e-68 228.3 0.1 9.3e-59 198.6 0.1 2.3 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.18 GBG81276.1 - 0.00076 19.8 0.1 0.0017 18.6 0.1 1.6 1 1 0 1 1 1 1 MutS domain III AAA_29 PF13555.6 GBG81276.1 - 0.024 14.4 0.1 0.057 13.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GBG81276.1 - 0.029 14.9 0.8 0.087 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF3487 PF11990.8 GBG81277.1 - 0.012 15.5 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) RT_RNaseH_2 PF17919.1 GBG81278.1 - 1.3e-34 118.2 0.0 2.4e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81278.1 - 4.5e-30 104.0 0.0 7.9e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81278.1 - 2.3e-11 43.7 0.1 3.7e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG81278.1 - 0.00093 19.1 1.3 0.0022 17.9 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG81279.1 - 9.1e-19 67.9 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG81280.1 - 0.019 15.5 0.1 0.05 14.2 0.1 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81280.1 - 0.027 15.1 0.1 0.082 13.6 0.1 1.8 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG81280.1 - 0.19 11.4 2.2 0.2 11.3 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like RVT_1 PF00078.27 GBG81281.1 - 4.2e-27 95.1 0.1 6.5e-27 94.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81281.1 - 2.6e-16 59.5 0.0 2.6e-13 49.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81281.1 - 4e-16 58.9 2.7 5.5e-16 58.4 0.0 2.7 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG81281.1 - 5.1e-09 36.4 0.0 1.7e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81281.1 - 2.7e-05 24.3 0.0 8.9e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG81281.1 - 3.6e-05 24.0 0.0 9.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG81282.1 - 7e-19 68.0 0.0 1.6e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81282.1 - 2.9e-07 30.3 0.0 4.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81282.1 - 0.0036 17.0 0.0 0.0082 15.8 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain MT0933_antitox PF14013.6 GBG81283.1 - 0.062 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 MT0933-like antitoxin protein XG_FTase PF03254.13 GBG81284.1 - 9.1e-76 255.4 0.0 2.9e-51 174.6 0.0 2.1 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase HemolysinCabind PF00353.19 GBG81284.1 - 8.7 6.5 16.7 1.2 9.2 6.7 1.9 1 1 1 2 2 2 0 RTX calcium-binding nonapeptide repeat (4 copies) NuA4 PF09340.10 GBG81286.1 - 3.8e-27 94.0 0.1 6e-27 93.3 0.1 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF4635 PF15466.6 GBG81286.1 - 0.0096 15.4 0.3 0.016 14.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4635) Enkurin PF13864.6 GBG81286.1 - 0.077 13.4 0.1 0.077 13.4 0.1 1.8 2 0 0 2 2 2 0 Calmodulin-binding RT_RNaseH PF17917.1 GBG81287.1 - 6.2e-20 71.4 0.2 1.5e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81287.1 - 1.7e-19 70.3 0.2 5e-11 42.5 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81287.1 - 1.8e-16 60.0 0.0 9.5e-16 57.7 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG81287.1 - 1e-11 44.7 0.0 3e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81287.1 - 4.7e-08 33.2 0.0 1.2e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81287.1 - 1.9e-05 24.8 0.0 5.1e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Keratin_B2_2 PF13885.6 GBG81288.1 - 0.00064 19.6 10.2 0.0014 18.5 10.2 1.6 1 0 0 1 1 1 1 Keratin, high sulfur B2 protein DUF659 PF04937.15 GBG81289.1 - 2.2e-20 73.1 0.0 3.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81289.1 - 0.0011 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rtf2 PF04641.12 GBG81290.1 - 6.8e-08 32.2 0.0 1.4e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 GBG81290.1 - 0.00099 19.2 0.0 0.0026 17.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 GBG81290.1 - 0.0046 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GBG81290.1 - 0.012 15.4 0.0 0.039 13.8 0.0 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SBP_bac_6 PF13343.6 GBG81290.1 - 0.085 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein RVT_1 PF00078.27 GBG81291.1 - 1.2e-20 74.0 0.1 1.5e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) XG_FTase PF03254.13 GBG81292.1 - 3.3e-71 240.3 0.0 7e-23 81.0 0.0 3.2 3 0 0 3 3 3 3 Xyloglucan fucosyltransferase N6_N4_Mtase PF01555.18 GBG81292.1 - 2.4e-07 30.7 0.0 6.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 DNA methylase Nop14 PF04147.12 GBG81292.1 - 0.0018 16.6 12.9 0.0034 15.7 12.9 1.4 1 0 0 1 1 1 1 Nop14-like family Cons_hypoth95 PF03602.15 GBG81292.1 - 0.015 15.0 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TMIE PF16038.5 GBG81292.1 - 0.13 12.2 0.3 0.46 10.4 0.3 2.0 1 0 0 1 1 1 0 TMIE protein CDC45 PF02724.14 GBG81292.1 - 0.33 9.2 10.6 0.69 8.1 10.6 1.4 1 0 0 1 1 1 0 CDC45-like protein SIT PF15330.6 GBG81292.1 - 0.77 10.2 2.8 0.71 10.3 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF659 PF04937.15 GBG81293.1 - 2.9e-26 92.2 0.0 4.3e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) XG_FTase PF03254.13 GBG81294.1 - 1.8e-72 244.5 0.0 1.6e-23 83.1 0.0 3.1 3 0 0 3 3 3 3 Xyloglucan fucosyltransferase DDE_Tnp_4 PF13359.6 GBG81297.1 - 4.7e-26 91.3 0.0 1.9e-25 89.4 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81297.1 - 6.8e-14 51.9 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81297.1 - 0.001 18.8 1.1 0.014 15.0 0.0 2.4 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG81297.1 - 0.037 14.4 0.1 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Transposase DDE domain DUF659 PF04937.15 GBG81299.1 - 2.9e-23 82.4 0.0 5.3e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG81300.1 - 4.2e-05 23.5 0.0 8.4e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) HMG_box PF00505.19 GBG81301.1 - 2.3e-35 120.8 6.6 4.9e-20 71.7 3.7 4.0 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GBG81301.1 - 3.2e-20 72.5 6.4 5.1e-13 49.4 3.1 4.3 3 1 0 3 3 3 2 HMG-box domain FmdE PF02663.14 GBG81301.1 - 6.6 6.8 6.9 22 5.1 6.9 1.9 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DUF2076 PF09849.9 GBG81302.1 - 0.0028 17.7 2.6 0.0028 17.7 2.6 3.3 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) RT_RNaseH_2 PF17919.1 GBG81303.1 - 1.7e-30 105.0 0.5 2.3e-29 101.4 0.1 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81303.1 - 1.1e-19 70.3 0.2 2.4e-19 69.2 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG81303.1 - 5e-18 65.3 0.1 1.8e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81303.1 - 1.7e-16 60.4 0.0 3.1e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81303.1 - 2.2e-07 31.1 0.0 1.2e-06 28.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG81303.1 - 0.029 14.3 2.1 0.083 12.9 2.1 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2 PF09337.10 GBG81303.1 - 0.068 13.4 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF3863 PF12979.7 GBG81303.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Xpo1 PF08389.12 GBG81304.1 - 1.4e-05 25.2 0.2 2.7e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 Exportin 1-like protein HEAT PF02985.22 GBG81304.1 - 0.0054 16.9 2.1 8.8 6.9 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 GBG81304.1 - 0.054 13.9 5.7 2.8 8.4 0.1 3.7 3 1 0 3 3 3 0 HEAT repeats SelB-wing_2 PF09106.11 GBG81304.1 - 0.081 13.1 0.7 0.63 10.3 0.0 2.9 3 0 0 3 3 3 0 Elongation factor SelB, winged helix LpxB PF02684.15 GBG81305.1 - 2e-05 23.6 0.1 0.35 9.7 0.1 3.1 3 0 0 3 3 3 3 Lipid-A-disaccharide synthetase LpxB PF02684.15 GBG81306.1 - 2.1e-05 23.6 0.1 0.35 9.7 0.1 3.1 3 0 0 3 3 3 3 Lipid-A-disaccharide synthetase Glyco_trans_2_3 PF13632.6 GBG81307.1 - 0.0061 16.5 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG81307.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 GBG81307.1 - 0.03 14.0 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 GBG81307.1 - 0.16 11.9 0.0 0.8 9.5 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase like family 2 CstA PF02554.14 GBG81308.1 - 9 5.1 6.7 17 4.2 0.3 2.7 1 1 2 3 3 3 0 Carbon starvation protein CstA Cupin_2 PF07883.11 GBG81311.1 - 8.2e-12 44.7 0.1 1.7e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Cupin domain DMSP_lyase PF16867.5 GBG81311.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DsbB PF02600.16 GBG81312.1 - 0.11 12.9 0.2 0.25 11.8 0.2 1.6 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB RT_RNaseH_2 PF17919.1 GBG81315.1 - 6.9e-27 93.4 0.0 1.1e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81315.1 - 6.5e-22 77.8 0.0 1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81315.1 - 4.3e-10 39.5 0.1 6.7e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Proteasome PF00227.26 GBG81317.1 - 3.7e-38 130.9 0.0 4.5e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Methyltransf_11 PF08241.12 GBG81318.1 - 0.044 14.4 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF3446 PF11928.8 GBG81318.1 - 0.26 11.6 30.0 1.2 9.5 8.8 3.7 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF2358 PF10184.9 GBG81319.1 - 2.7e-16 59.9 0.0 3.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 GBG81319.1 - 0.0042 17.7 0.0 0.011 16.4 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like domain RVT_1 PF00078.27 GBG81321.1 - 2e-12 47.1 0.0 3.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glu-tRNAGln PF02686.15 GBG81322.1 - 6.5e-10 39.2 0.0 1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit LRR_6 PF13516.6 GBG81324.1 - 1.8e-11 43.1 13.5 0.015 15.3 0.0 6.1 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 GBG81324.1 - 0.00016 21.8 14.2 1.6 9.6 0.1 7.9 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.7 GBG81324.1 - 0.1 13.0 0.0 0.1 13.0 0.0 5.2 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG81324.1 - 0.14 12.0 10.2 18 5.1 0.2 5.3 5 1 0 5 5 5 0 Leucine rich repeat Pkinase_Tyr PF07714.17 GBG81325.1 - 3.7e-39 134.6 0.0 4.9e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG81325.1 - 6.5e-39 133.9 0.0 8.6e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG81325.1 - 1.4e-05 25.1 0.0 0.00032 20.7 0.1 2.7 2 1 2 4 4 4 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GBG81326.1 - 2.5e-39 135.1 0.0 3.2e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG81326.1 - 4.4e-39 134.4 0.0 5.6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG81326.1 - 3.2e-05 24.0 0.0 0.00015 21.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family CHORD PF04968.12 GBG81327.1 - 2.5e-40 137.0 18.1 1.3e-22 80.2 6.6 2.4 2 0 0 2 2 2 2 CHORD SART-1 PF03343.13 GBG81328.1 - 1.9e-71 241.5 67.3 2.7e-52 178.2 56.2 6.7 1 1 4 6 6 6 2 SART-1 family Integrase_H2C2 PF17921.1 GBG81329.1 - 5.4e-20 71.3 0.1 1e-19 70.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG81329.1 - 1.1e-15 57.8 0.0 2.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81329.1 - 1e-09 38.6 0.0 3.5e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG81329.1 - 2.8e-09 36.9 0.0 5.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG81329.1 - 1.6e-08 35.1 0.0 4.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81329.1 - 5e-08 32.8 0.0 9.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG81329.1 - 7.1e-06 26.5 0.0 1.5e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG81329.1 - 0.0095 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Es2 PF09751.9 GBG81330.1 - 0.015 15.0 11.7 0.018 14.8 11.7 1.0 1 0 0 1 1 1 0 Nuclear protein Es2 Vac7 PF12751.7 GBG81330.1 - 0.052 13.0 2.6 0.077 12.4 2.6 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Atg14 PF10186.9 GBG81330.1 - 0.98 8.4 10.5 1.3 8.0 10.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DDRGK PF09756.9 GBG81330.1 - 6.3 6.3 29.6 0.21 11.1 23.1 1.7 2 0 0 2 2 2 0 DDRGK domain AAA_11 PF13086.6 GBG81330.1 - 6.5 6.5 13.0 9.9 5.9 13.0 1.3 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 GBG81331.1 - 0.00011 22.3 16.7 0.00011 22.3 16.7 6.1 7 0 0 7 7 7 4 Transcription factor IIA, alpha/beta subunit DUF308 PF03729.13 GBG81331.1 - 2.6 8.4 15.5 0.098 13.0 7.9 2.5 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) FAM76 PF16046.5 GBG81333.1 - 0.014 14.8 7.8 0.016 14.6 7.8 1.1 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 GBG81333.1 - 0.77 10.3 26.1 0.71 10.4 1.5 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4666 PF15697.5 GBG81333.1 - 3.4 8.4 7.4 1.6 9.4 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) PspB PF06667.12 GBG81333.1 - 5 7.2 12.3 5 7.2 0.2 3.2 3 1 0 3 3 3 0 Phage shock protein B Presenilin PF01080.17 GBG81333.1 - 7.3 5.2 5.4 7.3 5.2 5.4 1.2 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG81334.1 - 4.3e-28 98.4 0.0 6.8e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81334.1 - 1.4e-26 92.5 0.0 3e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81334.1 - 8.9e-15 54.9 0.1 8.5e-14 51.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG81334.1 - 9.7e-09 35.1 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81334.1 - 0.0012 19.4 0.0 0.0028 18.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81334.1 - 0.017 15.7 0.0 0.039 14.5 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RCDG1 PF15725.5 GBG81334.1 - 6.8 7.2 9.4 30 5.1 9.4 2.1 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein CcmH PF03918.14 GBG81336.1 - 1.2e-33 115.4 0.1 1.9e-33 114.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein RNA_pol_I_TF PF04090.12 GBG81336.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor HTH_48 PF17906.1 GBG81336.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Peptidase_C6 PF00851.18 GBG81336.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Helper component proteinase Myc_N PF01056.18 GBG81336.1 - 0.2 11.5 1.6 0.39 10.6 1.6 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Gastrin PF00918.17 GBG81336.1 - 0.23 12.4 2.9 0.4 11.7 1.1 2.3 2 1 0 2 2 2 0 Gastrin/cholecystokinin family Metallophos PF00149.28 GBG81338.1 - 9e-14 52.4 0.0 3.6e-13 50.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GBG81338.1 - 0.0017 18.6 0.1 0.0056 16.9 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain XPG_I PF00867.18 GBG81338.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 XPG I-region Metallophos PF00149.28 GBG81339.1 - 6.8e-14 52.8 0.0 2.8e-13 50.8 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GBG81339.1 - 0.0014 18.8 0.2 0.0048 17.1 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain XPG_I PF00867.18 GBG81339.1 - 0.13 12.6 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 XPG I-region CCD48 PF15799.5 GBG81340.1 - 0.23 9.7 8.0 0.29 9.4 8.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 NOA36 PF06524.12 GBG81340.1 - 7.1 5.9 8.7 8.1 5.7 8.7 1.1 1 0 0 1 1 1 0 NOA36 protein MttA_Hcf106 PF02416.16 GBG81341.1 - 9.9e-06 24.8 0.4 2e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 mttA/Hcf106 family NAD_binding_2 PF03446.15 GBG81342.1 - 9.5e-47 159.1 2.3 1.4e-46 158.5 2.3 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GBG81342.1 - 2.8e-30 105.0 0.2 5.1e-30 104.2 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GBG81342.1 - 1.4e-07 32.0 0.1 2.6e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 GBG81342.1 - 2.6e-07 30.8 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GBG81342.1 - 1.4e-05 24.5 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.17 GBG81342.1 - 0.0016 17.5 0.1 0.0021 17.1 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase ApbA PF02558.16 GBG81342.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 GBG81342.1 - 0.017 14.7 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 GBG81342.1 - 0.027 14.4 0.2 0.042 13.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GBG81342.1 - 0.028 14.7 0.0 0.18 12.1 0.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAP PF00956.18 GBG81343.1 - 1.2e-84 283.7 0.6 1.2e-84 283.7 0.6 1.6 2 0 0 2 2 1 1 Nucleosome assembly protein (NAP) DUF1840 PF08895.11 GBG81343.1 - 0.029 14.7 2.9 0.084 13.2 2.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Drc1-Sld2 PF11719.8 GBG81343.1 - 0.043 13.4 6.5 0.077 12.5 6.5 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein RNA_pol_3_Rpc31 PF11705.8 GBG81343.1 - 0.047 13.9 15.7 0.1 12.8 15.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 GBG81343.1 - 0.24 9.7 13.5 0.34 9.2 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RPA43_OB PF17875.1 GBG81343.1 - 0.37 11.4 3.4 0.76 10.4 3.4 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I BUD22 PF09073.10 GBG81343.1 - 0.4 10.0 15.3 0.66 9.3 15.3 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG81343.1 - 0.44 9.9 15.1 0.68 9.3 15.1 1.3 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GBG81343.1 - 0.47 9.5 24.4 0.74 8.9 24.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 GBG81343.1 - 0.49 10.1 16.1 0.03 14.1 10.8 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 GBG81343.1 - 0.92 9.0 10.5 1.5 8.3 10.5 1.4 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GBG81343.1 - 1.4 7.0 17.1 2.1 6.4 17.1 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 GBG81343.1 - 2 7.7 18.6 3.5 6.9 18.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 GBG81343.1 - 2.5 7.3 19.3 3.9 6.7 19.3 1.3 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 GBG81343.1 - 2.6 8.1 9.3 6 6.9 9.3 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 GBG81343.1 - 2.7 7.6 7.1 7.3 6.2 7.1 1.8 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.11 GBG81343.1 - 3.2 6.2 14.5 4.6 5.7 14.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SURF2 PF05477.11 GBG81343.1 - 3.9 7.1 7.4 6 6.5 7.4 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CENP-B_dimeris PF09026.10 GBG81343.1 - 4.1 7.8 27.5 0.19 12.1 20.9 2.2 2 0 0 2 2 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 GBG81343.1 - 4.6 5.2 21.2 7.1 4.6 21.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 GBG81343.1 - 6.8 4.6 9.5 9.7 4.1 9.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SET PF00856.28 GBG81344.1 - 6.1e-06 26.7 0.0 6.1e-06 26.7 0.0 2.7 2 1 0 2 2 2 1 SET domain Glyco_hydro_2_C PF02836.17 GBG81345.1 - 7e-102 340.6 0.1 1.3e-101 339.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 GBG81345.1 - 1.1e-64 218.4 0.0 1.5e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 GBG81345.1 - 5.3e-26 91.5 0.4 8.1e-22 77.9 0.1 3.2 2 1 1 3 3 3 2 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 GBG81345.1 - 7.1e-17 61.7 0.0 6.1e-16 58.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 GBG81345.1 - 6.8e-12 46.0 0.1 3.9e-10 40.4 0.0 3.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 2 Myb_DNA-bind_4 PF13837.6 GBG81346.1 - 9.4e-09 35.5 0.3 1.9e-08 34.5 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG81346.1 - 0.028 14.6 0.3 0.06 13.5 0.3 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG81348.1 - 9.6e-11 41.6 0.0 3.4e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 GBG81348.1 - 0.014 15.7 0.4 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 Transposase DDE domain Plant_tran PF04827.14 GBG81348.1 - 0.13 11.8 0.0 1.3 8.6 0.0 2.4 2 1 0 3 3 3 0 Plant transposon protein DUF659 PF04937.15 GBG81349.1 - 0.0015 18.4 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG81351.1 - 1.6e-16 60.1 0.4 6.4e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG81351.1 - 4.8e-11 42.4 0.0 9.1e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG81351.1 - 3.5e-10 40.1 0.0 1.5e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG81351.1 - 1.4e-05 25.2 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG81351.1 - 0.0094 16.2 0.1 0.019 15.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81351.1 - 0.032 14.3 0.1 0.056 13.5 0.1 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Pox_A_type_inc PF04508.12 GBG81352.1 - 3 7.8 23.4 0.58 10.1 1.5 6.3 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat GRP PF07172.11 GBG81353.1 - 6.6 7.5 24.6 11 6.8 24.5 1.5 1 1 0 1 1 1 0 Glycine rich protein family Integrase_H2C2 PF17921.1 GBG81354.1 - 3e-16 59.3 0.1 5.7e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG81354.1 - 1.9e-05 25.2 0.0 0.0002 22.0 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81354.1 - 0.00099 19.6 0.0 0.0037 17.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TMF_DNA_bd PF12329.8 GBG81354.1 - 0.007 16.3 8.4 0.007 16.3 8.4 4.2 2 2 1 4 4 4 1 TATA element modulatory factor 1 DNA binding Bacillus_HBL PF05791.11 GBG81354.1 - 0.53 10.1 5.5 6.5 6.6 0.1 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF948 PF06103.11 GBG81354.1 - 2 8.7 3.3 9.6 6.5 0.3 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Pex14_N PF04695.13 GBG81355.1 - 0.063 13.9 0.1 2.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 GBG81355.1 - 0.18 10.5 26.7 0.072 11.8 5.6 2.0 2 0 0 2 2 2 0 Presenilin DUF4366 PF14283.6 GBG81355.1 - 4.4 7.3 18.8 0.3 11.1 1.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Actin PF00022.19 GBG81356.1 - 6.5e-51 173.2 0.0 3.7e-24 85.1 0.1 3.5 3 0 0 3 3 3 3 Actin RVT_1 PF00078.27 GBG81356.1 - 6.2e-25 88.0 0.0 1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81356.1 - 8.2e-23 80.3 0.0 1.8e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81356.1 - 5e-22 78.2 0.0 1.1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81356.1 - 2.4e-09 37.4 0.0 8.3e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG81356.1 - 0.00022 21.0 0.5 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain MreB_Mbl PF06723.13 GBG81356.1 - 0.011 14.5 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein AP2 PF00847.20 GBG81356.1 - 0.018 15.2 0.8 0.21 11.9 0.2 2.8 2 0 0 2 2 2 0 AP2 domain DDE_Tnp_1 PF01609.21 GBG81356.1 - 0.05 13.2 0.2 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 Transposase DDE domain DUF659 PF04937.15 GBG81357.1 - 9.7e-11 41.7 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81357.1 - 0.047 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG81358.1 - 5.4e-24 84.9 0.0 9e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG81358.1 - 2.1e-07 31.4 0.3 2.8e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81358.1 - 2.3e-06 28.1 0.3 1.3e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG81358.1 - 0.0029 17.4 0.1 0.0056 16.5 0.1 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG81358.1 - 0.003 17.3 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81358.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease EspB PF05802.11 GBG81358.1 - 0.09 12.8 4.3 0.23 11.4 4.3 1.7 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF812 PF05667.11 GBG81358.1 - 0.5 9.2 5.0 0.92 8.3 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) RT_RNaseH_2 PF17919.1 GBG81359.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG81359.1 - 0.19 12.0 0.7 0.49 10.7 0.7 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Lipase_3 PF01764.25 GBG81362.1 - 5.2e-31 107.4 0.0 1.9e-18 66.7 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 GBG81362.1 - 0.0077 16.8 1.5 0.0077 16.8 1.5 3.2 1 1 2 3 3 3 1 Alpha/beta hydrolase family DUF2974 PF11187.8 GBG81362.1 - 0.024 14.2 0.1 0.84 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 GBG81362.1 - 0.086 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold MMR_HSR1 PF01926.23 GBG81363.1 - 1.4e-16 60.6 0.2 9.2e-14 51.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SDA1 PF05285.12 GBG81363.1 - 6.3e-06 25.8 38.8 0.00064 19.3 8.8 2.7 3 0 0 3 3 3 2 SDA1 FeoB_N PF02421.18 GBG81363.1 - 2.6e-05 23.8 0.0 0.0003 20.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GBG81363.1 - 0.00024 21.1 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase Nop14 PF04147.12 GBG81363.1 - 0.00039 18.8 46.0 0.028 12.6 13.3 2.2 2 0 0 2 2 2 2 Nop14-like family YL1 PF05764.13 GBG81363.1 - 0.0035 17.5 50.1 0.024 14.8 8.8 3.9 4 0 0 4 4 4 2 YL1 nuclear protein BSP_II PF05432.11 GBG81363.1 - 0.0054 16.5 7.6 0.0054 16.5 7.6 2.9 2 1 0 3 3 2 1 Bone sialoprotein II (BSP-II) DUF2052 PF09747.9 GBG81363.1 - 0.0062 16.7 5.0 0.0062 16.7 5.0 3.6 3 1 0 3 3 3 1 Coiled-coil domain containing protein (DUF2052) SpoIIIAH PF12685.7 GBG81363.1 - 0.058 13.2 11.6 1 9.1 3.0 2.5 2 0 0 2 2 2 0 SpoIIIAH-like protein SpoIIP PF07454.11 GBG81363.1 - 0.29 10.5 9.8 1.2 8.5 0.2 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 GBG81363.1 - 1.1 9.4 3.2 25 4.9 0.2 2.5 2 0 0 2 2 2 0 DDHD domain Mpp10 PF04006.12 GBG81363.1 - 1.1 7.6 44.0 0.0085 14.6 8.8 2.6 3 0 0 3 3 3 0 Mpp10 protein Zip PF02535.22 GBG81363.1 - 2.3 7.3 10.9 2.1 7.4 2.6 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.17 GBG81363.1 - 2.4 6.8 10.4 5 5.8 0.7 2.3 2 0 0 2 2 2 0 Presenilin Dynamin_N PF00350.23 GBG81363.1 - 2.4 8.2 12.9 3.9 7.5 4.1 4.0 3 1 0 3 3 3 0 Dynamin family XAP5 PF04921.14 GBG81363.1 - 3.8 7.3 18.7 1.9 8.3 4.7 2.6 2 0 0 2 2 2 0 XAP5, circadian clock regulator NOA36 PF06524.12 GBG81363.1 - 7 5.9 57.0 0.34 10.2 19.1 3.2 3 0 0 3 3 3 0 NOA36 protein Roughex PF06020.11 GBG81363.1 - 8.1 5.4 28.0 0.049 12.7 5.9 2.4 2 0 0 2 2 2 0 Drosophila roughex protein RNA_pol_Rpc4 PF05132.14 GBG81363.1 - 9.3 6.7 21.6 2 8.8 0.5 2.9 3 1 0 3 3 3 0 RNA polymerase III RPC4 Cellulase PF00150.18 GBG81364.1 - 1.3e-09 37.9 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) YqaJ PF09588.10 GBG81365.1 - 1.3e-18 67.6 0.0 3.2e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain DDHD PF02862.17 GBG81365.1 - 3.2 7.8 8.0 11 6.1 2.7 2.4 2 0 0 2 2 2 0 DDHD domain Asp_protease_2 PF13650.6 GBG81366.1 - 2.8e-06 27.9 0.0 3.5e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81366.1 - 0.00074 20.0 0.1 0.0026 18.3 0.1 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease PBP3 PF18056.1 GBG81366.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Penicillin Binding Protein 3 Domain Pkinase_Tyr PF07714.17 GBG81367.1 - 6.3e-35 120.7 0.1 9.9e-35 120.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG81367.1 - 2.8e-34 118.7 0.1 4.6e-34 118.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Malectin_like PF12819.7 GBG81367.1 - 2.6e-13 49.9 0.0 4.8e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 Malectin-like domain LRR_8 PF13855.6 GBG81367.1 - 2.7e-09 36.7 6.9 4.8e-09 35.8 6.9 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GBG81367.1 - 3.7e-09 36.7 16.8 4.7e-07 30.0 2.7 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG81367.1 - 1.3e-05 25.0 5.0 0.24 12.1 0.1 4.2 3 0 0 3 3 3 2 Leucine Rich Repeat Malectin PF11721.8 GBG81367.1 - 5.5e-05 23.3 0.0 0.0083 16.2 0.0 2.4 2 0 0 2 2 2 1 Malectin domain LRR_6 PF13516.6 GBG81367.1 - 0.00032 20.5 6.3 0.085 13.0 0.2 3.9 3 0 0 3 3 3 1 Leucine Rich repeat PIP49_C PF12260.8 GBG81367.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 EphA2_TM PF14575.6 GBG81367.1 - 0.002 18.9 0.0 0.03 15.2 0.0 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain ABC1 PF03109.16 GBG81367.1 - 0.029 14.6 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC1 family DUF1180 PF06679.12 GBG81367.1 - 0.043 14.2 0.1 0.084 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) APH PF01636.23 GBG81367.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cadherin_C_2 PF16492.5 GBG81367.1 - 0.48 11.2 1.7 11 6.8 0.1 3.0 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Glycolytic PF00274.19 GBG81370.1 - 1.9e-171 569.5 0.0 2.1e-171 569.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I RVT_1 PF00078.27 GBG81372.1 - 4.5e-25 88.5 0.1 8.4e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81372.1 - 9.9e-17 60.8 0.0 2.8e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG81372.1 - 5.8e-10 38.9 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG81372.1 - 1.9e-09 37.7 0.0 5.4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG81372.1 - 0.00021 21.5 0.0 0.00052 20.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG81372.1 - 0.12 13.1 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Glycolytic PF00274.19 GBG81373.1 - 5.2e-171 568.1 0.0 5.8e-171 567.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glycolytic PF00274.19 GBG81374.1 - 6.9e-171 567.7 0.0 7.7e-171 567.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Nop14 PF04147.12 GBG81375.1 - 1.7 6.7 11.6 2.4 6.3 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG81376.1 - 2.6e-33 115.4 0.1 5.1e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81376.1 - 2.7e-29 101.2 0.0 6.2e-29 100.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81376.1 - 2.8e-25 88.6 0.0 6.6e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81376.1 - 1.6e-12 47.4 0.1 3.2e-11 43.2 0.0 2.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81376.1 - 0.00047 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain eIF-1a PF01176.19 GBG81376.1 - 0.0097 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 gag-asp_proteas PF13975.6 GBG81377.1 - 4.8e-07 30.3 0.1 1.1e-06 29.1 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81377.1 - 4.7e-06 27.2 0.1 1.4e-05 25.6 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG81377.1 - 0.00052 19.8 0.1 0.00079 19.2 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81377.1 - 0.0028 17.4 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG81377.1 - 1.2 9.4 7.2 0.086 13.0 2.3 1.8 2 0 0 2 2 2 0 Zinc knuckle G5 PF07501.12 GBG81378.1 - 3.4 8.2 10.9 5.5 7.5 1.0 2.8 2 1 0 2 2 2 0 G5 domain RVT_1 PF00078.27 GBG81379.1 - 4.9e-32 111.2 0.2 7.3e-32 110.7 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG81379.1 - 0.13 12.3 0.1 2.3 8.3 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L34 SLT PF01464.20 GBG81380.1 - 2.3e-22 78.8 0.0 8e-14 51.3 0.0 2.2 2 0 0 2 2 2 2 Transglycosylase SLT domain EFhand_Ca_insen PF08726.10 GBG81380.1 - 0.052 13.6 0.0 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Ca2+ insensitive EF hand RT_RNaseH_2 PF17919.1 GBG81381.1 - 9.6e-35 118.6 0.1 1.8e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81381.1 - 2.4e-29 101.7 0.1 5e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81381.1 - 2.5e-16 59.9 0.0 4.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG81381.1 - 1.8e-05 24.6 0.1 3.5e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG81383.1 - 1.5e-05 25.2 1.9 0.06 13.6 0.0 4.0 3 1 1 4 4 4 2 Retrotransposon gag protein Pox_J1 PF03338.15 GBG81383.1 - 0.063 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus J1 protein Jnk-SapK_ap_N PF09744.9 GBG81383.1 - 0.56 10.4 9.9 0.075 13.3 2.3 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 RVT_1 PF00078.27 GBG81384.1 - 2e-23 83.1 0.0 4.2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81384.1 - 4.6e-14 52.3 0.0 1.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG81384.1 - 2.2e-13 50.4 0.0 6e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81384.1 - 5e-07 29.7 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG81384.1 - 0.031 13.4 0.0 0.073 12.2 0.0 1.6 1 0 0 1 1 1 0 Autophagy protein Apg17 CLIP1_ZNF PF16641.5 GBG81384.1 - 0.049 13.5 2.0 0.1 12.5 2.0 1.6 1 0 0 1 1 1 0 CLIP1 zinc knuckle CH_2 PF06294.11 GBG81384.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 CH-like domain in sperm protein DUF4604 PF15377.6 GBG81385.1 - 1.7 9.1 22.4 2.2 8.7 22.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Glypican PF01153.19 GBG81385.1 - 7.9 5.2 9.9 8.6 5.1 9.9 1.0 1 0 0 1 1 1 0 Glypican Myb_DNA-bind_4 PF13837.6 GBG81386.1 - 2.7e-05 24.4 0.2 4.3e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG81386.1 - 0.004 17.4 0.0 0.0072 16.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG81386.1 - 0.089 13.1 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Aa_trans PF01490.18 GBG81387.1 - 6.1e-16 58.1 13.9 4e-15 55.4 13.9 2.2 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GBG81387.1 - 0.0016 17.6 20.4 0.0061 15.7 12.1 3.4 3 1 0 3 3 3 2 Tryptophan/tyrosine permease family DUF3245 PF11595.8 GBG81388.1 - 9.4e-06 26.2 11.5 0.00023 21.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3245) FAM176 PF14851.6 GBG81388.1 - 1.3 8.7 6.5 0.25 11.0 2.7 1.7 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 GBG81388.1 - 5.5 7.4 8.9 2 8.9 4.9 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FeThRed_A PF02941.15 GBG81389.1 - 6.4e-24 83.9 0.1 1e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase variable alpha chain TPR_1 PF00515.28 GBG81390.1 - 2.4e-41 137.9 8.0 7.8e-07 28.7 0.1 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 GBG81390.1 - 6.9e-35 116.3 14.9 6.3e-06 25.9 0.1 9.1 10 0 0 10 10 9 7 Tetratricopeptide repeat DnaJ PF00226.31 GBG81390.1 - 1.9e-27 95.1 1.0 1.8e-26 92.0 0.3 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.6 GBG81390.1 - 1.9e-22 78.7 4.9 0.0088 15.7 0.0 6.6 4 1 2 6 6 6 6 TPR repeat TPR_8 PF13181.6 GBG81390.1 - 4.7e-21 73.2 5.5 0.016 15.4 0.0 8.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 GBG81390.1 - 1.8e-20 73.3 10.7 0.0057 17.3 0.0 7.1 5 2 0 7 7 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 GBG81390.1 - 4e-20 70.8 16.6 0.00039 21.0 0.1 8.4 4 3 5 9 9 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 GBG81390.1 - 7.7e-18 64.4 8.8 1.5e-06 28.3 0.8 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 GBG81390.1 - 1.2e-17 64.2 11.3 0.012 16.1 0.5 6.7 3 3 3 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 GBG81390.1 - 1.2e-13 51.2 16.0 0.017 15.4 0.0 7.0 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 GBG81390.1 - 3.3e-10 39.6 0.2 0.22 12.0 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG81390.1 - 9.3e-10 37.9 9.3 0.5 10.5 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 GBG81390.1 - 4.3e-09 36.4 12.7 0.018 15.7 0.1 6.8 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 GBG81390.1 - 1.3e-07 31.2 4.5 0.019 14.2 0.1 4.8 1 1 1 3 3 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 GBG81390.1 - 7.3e-07 28.5 1.4 0.15 11.5 0.1 4.4 5 0 0 5 5 4 2 SHNi-TPR ANAPC3 PF12895.7 GBG81390.1 - 1.3e-05 25.3 5.0 3.5 7.9 0.0 5.1 2 1 3 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 GBG81390.1 - 1.5e-05 25.0 2.6 0.83 9.8 0.3 4.6 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat PknG_TPR PF16918.5 GBG81390.1 - 0.0004 19.2 1.8 0.27 9.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase G tetratricopeptide repeat TOM20_plant PF06552.12 GBG81390.1 - 0.022 14.5 0.6 0.14 11.8 0.1 2.6 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 MAS20 PF02064.15 GBG81390.1 - 0.026 14.6 0.4 7.9 6.6 0.7 3.8 2 1 1 3 3 3 0 MAS20 protein import receptor NYD-SP12_N PF15015.6 GBG81390.1 - 0.038 12.4 0.0 0.077 11.3 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal NatB_MDM20 PF09797.9 GBG81390.1 - 0.041 12.8 0.1 2.8 6.8 0.1 2.4 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit BTAD PF03704.17 GBG81390.1 - 0.051 14.0 7.4 0.61 10.5 2.3 3.3 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 GBG81390.1 - 0.14 12.5 11.7 2.7 8.4 1.5 4.8 3 2 2 6 6 6 0 Tetratricopeptide repeat RLL PF10036.9 GBG81390.1 - 0.18 11.6 4.2 0.38 10.6 4.2 1.5 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein Glyco_trans_1_2 PF13524.6 GBG81390.1 - 0.32 11.4 1.6 7.1 7.1 0.3 2.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 MIT PF04212.18 GBG81390.1 - 0.69 10.0 7.0 11 6.2 0.1 4.2 4 1 1 5 5 4 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 GBG81390.1 - 0.8 10.2 7.8 42 4.6 0.1 4.3 3 2 2 5 5 5 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 GBG81390.1 - 1.6 8.7 11.6 23 5.0 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DDE_Tnp_4 PF13359.6 GBG81391.1 - 4.7e-22 78.4 0.0 6.5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81391.1 - 4.3e-14 52.6 0.0 1e-13 51.4 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein TetR_C_13 PF16925.5 GBG81391.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RVT_1 PF00078.27 GBG81392.1 - 6.9e-38 130.4 0.0 9.3e-37 126.7 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 GBG81392.1 - 0.0025 17.7 0.0 0.023 14.5 0.0 2.7 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GBG81392.1 - 0.032 13.8 0.1 0.075 12.5 0.1 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family ParD_antitoxin PF03693.14 GBG81394.1 - 0.19 12.2 1.0 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH TFIIA PF03153.13 GBG81395.1 - 0.01 15.9 7.1 0.015 15.3 7.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HTH_15 PF12324.8 GBG81395.1 - 0.17 11.9 1.3 21 5.2 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Ebola_NP PF05505.12 GBG81395.1 - 1.2 7.3 6.7 8.7 4.5 6.4 2.0 2 0 0 2 2 2 0 Ebola nucleoprotein Trypan_PARP PF05887.11 GBG81397.1 - 2.4e-05 24.3 59.6 1.8e+04 -13.9 59.6 3.0 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SATase_N PF06426.14 GBG81398.1 - 3.7e-36 123.7 0.1 5.1e-36 123.2 0.1 1.2 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 GBG81398.1 - 3e-15 55.3 10.7 4.7e-10 38.8 1.8 2.6 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GBG81398.1 - 0.0002 21.0 14.0 0.0019 17.9 3.0 2.7 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase FlaC_arch PF05377.11 GBG81399.1 - 0.2 12.1 0.2 0.2 12.1 0.2 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PALP PF00291.25 GBG81400.1 - 3.5e-65 220.3 1.1 3.5e-65 220.3 1.1 1.9 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 GBG81400.1 - 0.011 15.8 0.1 0.011 15.8 0.1 2.6 3 0 0 3 3 3 0 Zinc-binding dehydrogenase DUF659 PF04937.15 GBG81401.1 - 7.7e-31 107.0 0.2 1.2e-30 106.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG81402.1 - 6.9e-24 83.8 0.0 1.2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81402.1 - 4.3e-22 78.4 0.0 7.6e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81402.1 - 8.9e-09 35.2 0.1 1.3e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG81402.1 - 0.19 9.9 8.9 0.24 9.5 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG81402.1 - 1.1 8.7 11.1 1.4 8.2 11.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG81402.1 - 6 5.0 10.0 8.7 4.5 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Integrase_H2C2 PF17921.1 GBG81404.1 - 4.8e-18 65.0 1.9 1.1e-17 63.9 1.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81404.1 - 3.1e-15 56.4 0.0 6.8e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1223 PF06764.11 GBG81404.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) zf-CCHC PF00098.23 GBG81404.1 - 1.8 8.8 7.1 0.12 12.5 1.9 1.8 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG81405.1 - 9.9e-24 83.3 0.0 1.7e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81405.1 - 1.1e-21 77.1 0.0 1.9e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81405.1 - 4.6e-18 65.1 0.0 9.9e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81405.1 - 2.9e-06 27.4 0.1 1.2e-05 25.5 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG81405.1 - 0.078 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger EKR PF10371.9 GBG81406.1 - 0.11 12.4 0.0 7.7 6.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF285 PF03382.14 GBG81406.1 - 1.2 8.9 4.3 62 3.4 0.2 3.5 2 1 1 3 3 3 0 Mycoplasma protein of unknown function, DUF285 Thioredoxin PF00085.20 GBG81407.1 - 7.7e-20 70.8 0.0 1.3e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG81407.1 - 5.9e-08 33.1 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 GBG81407.1 - 0.0048 16.7 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 GBG81407.1 - 0.0096 15.8 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 GBG81407.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_8 PF13905.6 GBG81407.1 - 0.021 15.1 0.0 0.41 11.0 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 GBG81407.1 - 0.031 14.5 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 GBG81407.1 - 0.046 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Redoxin OST3_OST6 PF04756.13 GBG81407.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF2457 PF10446.9 GBG81407.1 - 0.85 8.7 17.9 2 7.5 17.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Methyltransf_22 PF13383.6 GBG81408.1 - 1.5e-21 77.2 0.0 1e-18 67.9 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain DUF5057 PF16480.5 GBG81409.1 - 0.53 9.6 7.0 0.11 11.8 3.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5057) BSP_II PF05432.11 GBG81409.1 - 2.1 8.0 20.2 0.17 11.5 7.9 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) SRP-alpha_N PF04086.13 GBG81409.1 - 2.4 8.0 23.5 0.95 9.3 11.9 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal WD40 PF00400.32 GBG81410.1 - 0.056 14.3 1.4 0.23 12.4 0.3 2.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Chromo PF00385.24 GBG81411.1 - 1.9e-12 46.9 0.0 3.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG81411.1 - 1.3e-09 38.2 0.0 3.5e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Methyltransf_25 PF13649.6 GBG81413.1 - 5.4e-15 55.9 0.1 2.2e-12 47.5 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG81413.1 - 4.4e-13 49.7 0.2 3e-12 47.0 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG81413.1 - 2.7e-09 37.0 0.0 1.1e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 GBG81413.1 - 6.4e-05 22.4 0.1 0.00032 20.2 0.0 2.1 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Ubie_methyltran PF01209.18 GBG81413.1 - 0.0001 21.7 0.1 0.0002 20.8 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 GBG81413.1 - 0.16 11.6 0.1 0.46 10.0 0.1 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Zip PF02535.22 GBG81413.1 - 3.1 6.9 13.3 6 6.0 13.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Histone PF00125.24 GBG81414.1 - 1.4e-07 32.0 0.3 1.4e-07 32.0 0.3 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PikAIV_N PF18605.1 GBG81415.1 - 0.0071 15.9 7.9 0.071 12.7 0.8 3.5 3 0 0 3 3 3 2 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain VIT PF08487.10 GBG81415.1 - 0.75 10.0 8.2 0.2 11.9 4.3 2.0 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Casc1_N PF15927.5 GBG81415.1 - 3.3 7.4 30.3 4.2 7.0 17.9 2.3 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus RVT_1 PF00078.27 GBG81416.1 - 7.3e-33 113.9 0.1 1.3e-32 113.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81416.1 - 6.3e-30 103.2 0.0 1.3e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81416.1 - 8.1e-27 93.6 0.1 1.8e-26 92.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81416.1 - 2.8e-10 40.2 0.0 1.1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG81417.1 - 6.1e-32 109.6 0.1 1.9e-31 108.1 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81417.1 - 3.6e-28 97.9 0.0 3.2e-27 94.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81417.1 - 1.3e-24 86.9 0.1 5e-24 85.0 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81417.1 - 3.1e-17 62.4 0.6 6.5e-17 61.4 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81417.1 - 7e-12 45.6 0.0 1.5e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain MscS_porin PF12795.7 GBG81417.1 - 6.1 6.3 6.6 2.5 7.6 0.8 3.3 4 0 0 4 4 4 0 Mechanosensitive ion channel porin domain Asp_protease_2 PF13650.6 GBG81419.1 - 0.0048 17.5 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81419.1 - 0.0052 17.3 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG81419.1 - 0.046 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1664 PF07889.12 GBG81419.1 - 0.55 10.3 3.8 5.7 7.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) RT_RNaseH_2 PF17919.1 GBG81420.1 - 9.7e-34 115.4 0.0 1.9e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81420.1 - 3.4e-29 101.2 0.1 7.3e-29 100.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81420.1 - 6.4e-16 58.2 0.2 1.3e-15 57.2 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81420.1 - 3e-14 53.2 0.0 9.3e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG81420.1 - 0.00015 21.4 0.0 0.00031 20.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81421.1 - 2.4e-34 117.4 0.0 3.8e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81421.1 - 2.9e-28 98.2 0.1 6.8e-28 97.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81421.1 - 3.3e-20 72.0 0.1 3.3e-20 72.0 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG81421.1 - 0.00045 20.4 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF1904 PF08921.11 GBG81421.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) Mcp5_PH PF12814.7 GBG81421.1 - 0.13 12.3 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology zf-rbx1 PF12678.7 GBG81421.1 - 0.16 12.3 0.4 0.46 10.8 0.1 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain MbeD_MobD PF04899.12 GBG81422.1 - 2.3 8.4 6.6 20 5.4 4.9 3.1 2 1 0 2 2 2 0 MbeD/MobD like RT_RNaseH_2 PF17919.1 GBG81423.1 - 4.4e-24 84.4 0.0 2.5e-23 82.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81423.1 - 9.6e-14 51.5 0.0 4.1e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81423.1 - 4.1e-12 46.1 0.1 8.2e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CHASE6_C PF17150.4 GBG81423.1 - 0.13 12.9 3.6 8.5 7.1 0.1 4.0 3 1 1 4 4 4 0 C-terminal domain of two-partite extracellular sensor domain Leader_Trp PF08255.11 GBG81423.1 - 0.14 12.1 0.8 0.44 10.6 0.8 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide Flot PF15975.5 GBG81423.1 - 9.9 6.4 15.5 61 3.8 15.1 2.5 2 1 0 2 2 2 0 Flotillin TIG PF01833.24 GBG81424.1 - 2.2e-22 78.9 21.7 3.1e-09 36.8 1.5 3.4 3 0 0 3 3 3 3 IPT/TIG domain Anth_Ig PF05587.13 GBG81424.1 - 1.1 9.7 4.3 0.76 10.1 1.0 2.4 3 0 0 3 3 3 0 Anthrax receptor extracellular domain Integrase_H2C2 PF17921.1 GBG81425.1 - 1.5e-15 57.1 0.0 2.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81425.1 - 5.9e-15 55.5 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81425.1 - 0.026 14.8 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG81426.1 - 1.2e-35 123.1 0.1 1.9e-35 122.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81426.1 - 1.5e-29 102.0 0.0 9.5e-29 99.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81426.1 - 2.5e-28 98.4 0.0 8.9e-28 96.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81426.1 - 0.00057 19.9 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain PA26 PF04636.13 GBG81426.1 - 1.1 8.1 8.2 1.6 7.5 8.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RT_RNaseH_2 PF17919.1 GBG81427.1 - 1.1e-54 182.7 0.0 1e-30 105.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81427.1 - 3.6e-50 168.6 0.1 6.1e-27 94.0 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81427.1 - 5.1e-40 137.3 1.2 1.7e-29 102.9 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81427.1 - 1.6e-25 89.0 3.7 4.3e-16 58.8 0.0 3.1 3 0 0 3 3 3 2 Integrase zinc binding domain rve PF00665.26 GBG81427.1 - 4.3e-16 59.2 0.0 1.1e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81427.1 - 2.5e-08 34.4 0.0 7.5e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81427.1 - 2.4e-06 28.1 0.0 6.9e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG81427.1 - 0.00014 22.0 0.1 0.0086 16.3 0.0 3.0 2 0 0 2 2 2 1 H2C2 zinc finger DUF1758 PF05585.12 GBG81427.1 - 0.0088 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG81427.1 - 0.01 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG81427.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG81428.1 - 0.025 14.9 7.6 0.19 12.1 0.6 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein TFIIA PF03153.13 GBG81428.1 - 8.8 6.2 17.5 15 5.4 17.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH PF17917.1 GBG81430.1 - 1.1e-20 73.8 0.5 7.8e-20 71.1 0.2 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81430.1 - 6.8e-12 45.3 0.0 1.8e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81431.1 - 9.2e-64 215.0 0.1 1.6e-33 116.1 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81431.1 - 5.2e-31 106.6 0.0 1.1e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81431.1 - 1.7e-30 105.4 0.1 3.6e-30 104.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81431.1 - 2.3e-14 53.3 0.1 5.4e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG81431.1 - 1.7e-06 27.8 0.0 4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81431.1 - 1.8e-05 25.3 0.0 3.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81431.1 - 0.001 19.6 0.0 0.0027 18.2 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG81431.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Phage_GPO PF05929.11 GBG81431.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SpoOE-like PF09388.10 GBG81431.1 - 0.24 11.3 1.0 32 4.5 0.3 3.1 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Glyoxalase_6 PF18029.1 GBG81432.1 - 9.2 7.1 8.8 5.8 7.7 0.9 3.9 4 0 0 4 4 4 0 Glyoxalase-like domain RT_RNaseH_2 PF17919.1 GBG81433.1 - 1.5e-24 85.9 0.0 4.4e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81433.1 - 6.3e-24 84.3 0.0 1.9e-23 82.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81433.1 - 2.5e-19 69.1 0.3 6.3e-19 67.8 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81433.1 - 3.3e-10 40.2 0.0 3.8e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG81433.1 - 0.00067 19.8 0.0 0.0022 18.2 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG81433.1 - 0.0025 17.7 0.1 0.0052 16.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FlxA PF14282.6 GBG81433.1 - 5.2 7.1 13.6 0.081 12.9 1.3 2.7 2 0 0 2 2 2 0 FlxA-like protein RVT_1 PF00078.27 GBG81434.1 - 2.1e-64 217.1 0.3 2.2e-35 122.2 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81434.1 - 6.8e-31 106.3 0.0 5.1e-19 68.2 0.0 3.1 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81434.1 - 6.1e-27 94.0 0.0 1.4e-16 60.7 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81434.1 - 1.8e-19 69.6 0.2 4.6e-19 68.3 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG81434.1 - 0.0078 16.5 0.0 5.3 7.4 0.0 3.9 3 0 0 3 3 3 1 Retrotransposon gag protein MREG PF15812.5 GBG81434.1 - 0.015 15.6 1.0 0.042 14.2 1.0 1.7 1 0 0 1 1 1 0 Melanoregulin zf-H2C2 PF09337.10 GBG81434.1 - 0.043 14.0 0.1 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger REV PF00424.18 GBG81434.1 - 0.81 9.7 4.0 1.7 8.7 0.1 3.2 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) RT_RNaseH_2 PF17919.1 GBG81435.1 - 1.7e-27 95.3 0.0 3.7e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81435.1 - 2e-25 89.1 0.0 5.2e-25 87.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81435.1 - 1.1e-07 31.9 2.2 3e-07 30.4 2.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81435.1 - 5e-06 26.7 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG81435.1 - 4.3e-05 23.4 3.2 4.3e-05 23.4 3.2 2.2 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG81435.1 - 0.00087 19.9 0.0 0.0025 18.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81435.1 - 0.0026 18.3 0.0 0.0085 16.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2249 PF10006.9 GBG81435.1 - 0.0062 16.4 0.0 2.3 8.1 0.0 3.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2249) RVP_2 PF08284.11 GBG81435.1 - 0.0079 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GBG81435.1 - 0.037 13.8 4.1 0.083 12.7 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 GBG81435.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Nop14 PF04147.12 GBG81436.1 - 0.84 7.8 9.0 1 7.5 9.0 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG81436.1 - 1.8 6.8 7.5 2.2 6.5 7.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG81437.1 - 9.2e-42 143.1 0.3 3.1e-20 72.7 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG81437.1 - 4.4e-19 68.8 0.0 7.3e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG81437.1 - 9.9e-15 54.4 0.1 4.3e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81437.1 - 1.1e-07 32.0 0.0 4.8e-07 30.0 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain TIG PF01833.24 GBG81437.1 - 5.4e-06 26.4 0.3 1.3e-05 25.1 0.3 1.6 1 0 0 1 1 1 1 IPT/TIG domain RT_RNaseH PF17917.1 GBG81437.1 - 0.00058 20.1 0.0 0.0019 18.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mito_carr PF00153.27 GBG81438.1 - 1.4e-05 24.9 0.2 3.3e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial carrier protein Mito_carr PF00153.27 GBG81440.1 - 1.6e-55 185.0 4.3 3.8e-26 90.8 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF659 PF04937.15 GBG81441.1 - 4.3e-31 107.8 2.3 7e-31 107.2 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DGF-1_C PF11040.8 GBG81441.1 - 0.013 15.4 0.7 0.042 13.9 0.2 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DivIC PF04977.15 GBG81442.1 - 4.4 7.1 11.0 0.76 9.6 5.3 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 GBG81442.1 - 5.7 7.5 8.5 82 3.7 5.1 2.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mito_carr PF00153.27 GBG81443.1 - 5.9e-08 32.5 0.0 6.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Fur_reg_FbpB PF13040.6 GBG81443.1 - 0.02 14.5 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 Fur-regulated basic protein B RVT_1 PF00078.27 GBG81444.1 - 1.1e-26 93.8 0.0 2.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81444.1 - 1.2e-17 63.7 0.3 2.9e-17 62.5 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF4392 PF14336.6 GBG81444.1 - 0.017 14.6 0.1 0.75 9.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4392) DUF4187 PF13821.6 GBG81444.1 - 0.14 11.9 5.1 0.05 13.4 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) RVT_1 PF00078.27 GBG81445.1 - 1.3e-27 96.8 0.0 3e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81445.1 - 2.3e-22 78.9 0.0 8.7e-22 77.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81445.1 - 2.8e-13 50.0 0.0 8.6e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81445.1 - 1.6e-08 34.8 0.0 4.5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG81445.1 - 1.3e-05 25.8 0.0 4e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81445.1 - 6.7e-05 23.4 0.0 0.00018 22.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81445.1 - 0.00021 21.1 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81445.1 - 0.0035 17.1 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG81445.1 - 0.0042 17.3 0.0 0.054 13.8 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein Dynamitin PF04912.14 GBG81445.1 - 0.23 10.7 2.2 0.48 9.7 2.2 1.4 1 0 0 1 1 1 0 Dynamitin Not3 PF04065.15 GBG81445.1 - 0.56 9.6 2.5 2.1 7.7 0.0 2.7 3 0 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Integrase_H2C2 PF17921.1 GBG81446.1 - 6.1e-17 61.5 2.4 8.5e-17 61.0 0.1 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG81446.1 - 6.7e-11 42.4 0.0 2e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG81446.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG81446.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Mito_carr PF00153.27 GBG81447.1 - 1.2e-22 79.6 0.5 3.3e-21 75.0 0.1 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3824 PF12868.7 GBG81449.1 - 7 7.3 9.1 16 6.1 9.1 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) RT_RNaseH_2 PF17919.1 GBG81450.1 - 8.2e-19 67.5 0.0 1.5e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81450.1 - 8.1e-15 54.9 0.1 1.2e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81450.1 - 3.7e-07 30.4 0.0 6.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase EMP70 PF02990.16 GBG81452.1 - 1.4e-167 558.5 21.6 1.8e-167 558.2 21.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 IncF PF17626.2 GBG81452.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.2 3 0 0 3 3 3 0 Inclusion membrane protein F EVC2_like PF12297.8 GBG81452.1 - 1.9 7.1 4.0 20 3.7 0.0 2.3 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein RVT_1 PF00078.27 GBG81453.1 - 1.3e-07 31.4 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG81453.1 - 9e-06 25.5 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81453.1 - 0.0064 17.1 0.0 0.019 15.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81453.1 - 0.0085 16.6 0.1 0.09 13.4 0.0 2.7 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF4392 PF14336.6 GBG81453.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF1758 PF05585.12 GBG81453.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG81453.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG81454.1 - 1.3e-21 76.9 0.0 2.9e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81454.1 - 5.2e-21 74.6 0.0 1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81454.1 - 1.9e-08 34.1 0.0 3.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81454.1 - 3.4e-08 33.7 0.0 1.1e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain TFIIE-A_C PF11521.8 GBG81454.1 - 7.5 6.9 6.8 8.2 6.8 0.4 2.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha RVT_1 PF00078.27 GBG81455.1 - 1.7e-21 76.7 0.1 3.4e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81455.1 - 1.8e-16 60.0 0.5 3.8e-16 58.9 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG81455.1 - 0.073 13.4 2.1 0.18 12.1 0.1 2.7 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81457.1 - 2e-32 111.2 0.0 4.8e-32 110.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81457.1 - 8.6e-29 99.9 0.1 2.1e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81457.1 - 6.2e-10 39.0 0.1 5e-07 29.4 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG81457.1 - 0.00011 22.7 0.0 0.00049 20.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81457.1 - 0.0065 17.1 0.0 0.024 15.2 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease rve PF00665.26 GBG81457.1 - 0.041 14.1 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain HAUS6_N PF14661.6 GBG81457.1 - 0.052 13.1 0.3 0.14 11.7 0.3 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FAM76 PF16046.5 GBG81457.1 - 0.14 11.5 0.8 0.27 10.6 0.8 1.3 1 0 0 1 1 1 0 FAM76 protein Asp_protease PF09668.10 GBG81457.1 - 0.2 11.5 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG81457.1 - 1.1 9.6 0.0 1.1 9.6 0.0 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein Slx4 PF09494.10 GBG81459.1 - 0.038 13.9 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease RT_RNaseH PF17917.1 GBG81461.1 - 3e-13 50.0 0.0 8.7e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81461.1 - 2.8e-10 40.1 0.0 7e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81463.1 - 2.3e-12 46.8 0.2 5.8e-12 45.5 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81463.1 - 5.4e-12 46.0 0.0 1.2e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG81463.1 - 1.5e-08 34.5 0.0 2.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG81463.1 - 0.015 15.6 0.0 0.72 10.2 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Paz_1 PF18349.1 GBG81465.1 - 0.063 13.2 0.1 0.14 12.1 0.1 1.6 2 0 0 2 2 2 0 PAZ domain ATP-grasp_4 PF13535.6 GBG81465.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 1 0 1 1 1 0 ATP-grasp domain RVT_1 PF00078.27 GBG81466.1 - 3.2e-29 102.0 0.0 4.8e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG81466.1 - 0.028 14.4 0.0 6.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L34 HTH_20 PF12840.7 GBG81466.1 - 0.3 11.2 1.6 7.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Nop14 PF04147.12 GBG81467.1 - 0.082 11.1 39.4 0.09 11.0 39.4 1.0 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 GBG81467.1 - 0.85 9.1 25.3 1 8.9 25.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein TFIIA PF03153.13 GBG81467.1 - 2.9 7.8 19.5 3.6 7.5 19.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 GBG81467.1 - 2.9 8.0 6.0 3.6 7.7 6.0 1.3 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 GBG81467.1 - 6.4 5.6 12.4 6.7 5.6 12.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Paf1 PF03985.13 GBG81467.1 - 6.8 5.6 40.6 8.3 5.3 40.6 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 GBG81468.1 - 0.0022 16.4 7.1 0.0028 16.0 7.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Intg_mem_TP0381 PF09529.10 GBG81468.1 - 0.0022 17.6 0.2 0.0039 16.7 0.2 1.3 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) Ctr PF04145.15 GBG81468.1 - 0.004 17.8 2.0 0.004 17.8 2.0 1.9 1 1 1 2 2 2 1 Ctr copper transporter family EphA2_TM PF14575.6 GBG81468.1 - 0.013 16.4 0.1 0.013 16.4 0.1 2.4 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain SR-25 PF10500.9 GBG81468.1 - 0.019 14.6 43.6 0.29 10.7 6.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Conotoxin PF02950.17 GBG81468.1 - 0.02 15.9 14.5 0.062 14.3 1.3 2.6 2 0 0 2 2 2 0 Conotoxin RPN2_C PF18004.1 GBG81468.1 - 0.02 14.8 24.1 0.021 14.7 15.2 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Baculo_11_kDa PF06143.11 GBG81468.1 - 0.027 14.1 1.0 0.027 14.1 1.0 1.9 2 1 0 2 2 1 0 Baculovirus 11 kDa family Herpes_gE PF02480.16 GBG81468.1 - 0.034 12.9 0.2 0.054 12.2 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FGF-BP1 PF06473.12 GBG81468.1 - 0.042 13.7 20.3 0.5 10.2 0.3 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) TauE PF01925.19 GBG81468.1 - 0.045 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF92 PF01940.16 GBG81468.1 - 0.073 12.5 0.0 0.073 12.5 0.0 2.2 2 1 0 2 2 1 0 Integral membrane protein DUF92 Oxidored_q3 PF00499.20 GBG81468.1 - 0.089 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Sulf_transp PF04143.14 GBG81468.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Sulphur transport Eapp_C PF10238.9 GBG81468.1 - 0.097 12.7 11.6 0.6 10.2 8.5 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Atrophin-1 PF03154.15 GBG81468.1 - 0.11 10.7 9.4 0.18 10.1 9.4 1.3 1 0 0 1 1 1 0 Atrophin-1 family Rtf2 PF04641.12 GBG81468.1 - 0.15 11.4 24.4 0.28 10.5 13.8 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger DUF3413 PF11893.8 GBG81468.1 - 0.17 11.1 0.2 0.3 10.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) RPOL_N PF14700.6 GBG81468.1 - 0.18 11.1 12.9 0.27 10.6 12.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal SIT PF15330.6 GBG81468.1 - 0.19 12.2 0.4 0.19 12.2 0.4 2.4 2 0 0 2 2 1 0 SHP2-interacting transmembrane adaptor protein, SIT MDM10 PF12519.8 GBG81468.1 - 0.24 10.2 5.9 0.3 9.9 5.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 BRF1 PF07741.13 GBG81468.1 - 0.26 11.6 25.6 2 8.8 0.2 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF3464 PF11947.8 GBG81468.1 - 0.28 11.0 19.1 8.6 6.1 16.3 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 MscL PF01741.18 GBG81468.1 - 0.35 11.2 0.2 0.35 11.2 0.2 2.4 2 1 0 2 2 1 0 Large-conductance mechanosensitive channel, MscL 7TM_GPCR_Srx PF10328.9 GBG81468.1 - 0.39 10.3 0.1 0.39 10.3 0.1 2.0 2 0 0 2 2 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DNApol_Exo PF18136.1 GBG81468.1 - 0.59 9.2 8.6 0.17 11.0 3.9 1.9 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain LicD PF04991.13 GBG81468.1 - 0.65 10.1 11.7 11 6.1 7.7 2.1 2 0 0 2 2 2 0 LicD family G0-G1_switch_2 PF15103.6 GBG81468.1 - 0.67 10.4 14.7 1.7 9.1 10.4 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Scs3p PF10261.9 GBG81468.1 - 0.83 9.1 5.3 0.35 10.3 3.1 1.5 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Gaa1 PF04114.14 GBG81468.1 - 0.94 8.4 2.9 1.4 7.8 2.9 1.3 1 1 0 1 1 1 0 Gaa1-like, GPI transamidase component MAP17 PF15807.5 GBG81468.1 - 0.94 9.7 18.6 3.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF3807 PF12720.7 GBG81468.1 - 1.1 9.5 22.6 0.24 11.6 13.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) PRC2_HTH_1 PF18118.1 GBG81468.1 - 1.1 10.1 15.6 15 6.5 12.6 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Vfa1 PF08432.10 GBG81468.1 - 1.3 9.3 28.2 2.2 8.6 20.7 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ni_hydr_CYTB PF01292.20 GBG81468.1 - 1.4 8.5 4.7 0.93 9.1 0.3 2.1 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 GNAT_acetyltr_2 PF13718.6 GBG81468.1 - 1.5 8.2 6.0 1.6 8.1 4.0 1.8 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF1764 PF08576.10 GBG81468.1 - 2.1 9.3 26.0 7 7.6 18.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Connexin PF00029.19 GBG81468.1 - 2.3 7.9 19.8 4.1 7.1 0.2 2.1 2 0 0 2 2 2 0 Connexin FAM176 PF14851.6 GBG81468.1 - 2.5 7.8 13.8 0.99 9.1 4.5 2.6 2 1 1 3 3 3 0 FAM176 family NDUF_B4 PF07225.12 GBG81468.1 - 2.5 8.0 11.4 7 6.6 11.4 1.7 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Borrelia_P83 PF05262.11 GBG81468.1 - 2.9 6.3 13.6 4.2 5.7 13.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Agouti PF05039.12 GBG81468.1 - 3.7 8.3 12.8 12 6.7 7.9 2.2 2 0 0 2 2 2 0 Agouti protein RNA_pol_Rpc4 PF05132.14 GBG81468.1 - 3.9 7.9 17.2 14 6.1 14.2 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 tRNA_synt_1c_R2 PF04557.15 GBG81468.1 - 4 8.4 29.5 7.7 7.5 2.4 2.3 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Serinc PF03348.15 GBG81468.1 - 4 6.2 8.8 4 6.3 2.8 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) eIF3_subunit PF08597.10 GBG81468.1 - 4.3 7.2 34.9 4.6 7.1 23.2 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit MMM1 PF10296.9 GBG81468.1 - 4.5 6.2 8.0 27 3.7 0.0 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 RMP PF14996.6 GBG81468.1 - 4.6 7.4 14.0 7.1 6.8 8.0 2.1 2 0 0 2 2 2 0 Retinal Maintenance Jak1_Phl PF17887.1 GBG81468.1 - 4.8 7.1 21.4 3.4 7.6 1.1 2.3 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain NARP1 PF12569.8 GBG81468.1 - 5.8 5.7 27.2 0.038 12.9 14.0 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Rrn6 PF10214.9 GBG81468.1 - 6.4 5.1 15.2 9 4.6 15.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC24_OB1 PF17246.2 GBG81468.1 - 8 6.6 11.4 7.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 OSTbeta PF15048.6 GBG81468.1 - 8.9 6.5 16.3 0.25 11.5 0.9 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF1754 PF08555.10 GBG81468.1 - 9.8 7.0 45.7 6.5 7.6 9.7 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PsbP PF01789.16 GBG81469.1 - 3e-06 27.4 0.0 6.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 PsbP RVP_2 PF08284.11 GBG81470.1 - 1e-06 28.6 0.0 2.3e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81470.1 - 8.6e-06 26.3 0.0 2.4e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81470.1 - 0.00015 22.3 0.1 0.00073 20.1 0.1 2.2 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG81470.1 - 0.031 14.1 0.0 0.081 12.7 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease Es2 PF09751.9 GBG81470.1 - 0.078 12.7 16.3 0.12 12.1 16.3 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 RVP PF00077.20 GBG81470.1 - 0.092 13.1 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 GBG81471.1 - 7.4e-07 29.4 0.0 2.1e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_5 PF14787.6 GBG81471.1 - 0.089 12.5 1.0 0.17 11.6 1.0 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger KR PF08659.10 GBG81471.1 - 0.13 12.2 1.2 0.77 9.6 0.6 2.4 3 0 0 3 3 3 0 KR domain Atg14 PF10186.9 GBG81471.1 - 0.17 11.0 5.4 0.38 9.8 5.4 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Glutaredoxin2_C PF04399.13 GBG81471.1 - 0.22 11.3 1.1 5.8 6.8 0.0 2.8 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain ImpA_N PF06812.12 GBG81471.1 - 0.24 11.5 1.6 0.82 9.8 1.6 2.0 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system zf-CCHC PF00098.23 GBG81471.1 - 0.55 10.4 3.9 1.2 9.3 3.9 1.6 1 0 0 1 1 1 0 Zinc knuckle YabA PF06156.13 GBG81471.1 - 3.1 8.5 10.2 0.26 11.9 3.6 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Myb_DNA-bind_4 PF13837.6 GBG81472.1 - 3.6e-08 33.7 1.6 5.5e-08 33.1 1.6 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG81472.1 - 0.23 11.7 3.0 1.7 8.9 3.0 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain RVT_1 PF00078.27 GBG81473.1 - 5.9e-24 84.8 0.0 8.7e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA PF00004.29 GBG81474.1 - 1.9e-42 144.8 0.0 6.8e-39 133.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 GBG81474.1 - 1.8e-11 43.9 0.0 3.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain IstB_IS21 PF01695.17 GBG81474.1 - 2.5e-09 37.1 0.0 1.1e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_lid_3 PF17862.1 GBG81474.1 - 8e-09 35.2 0.1 4e-08 32.9 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 GBG81474.1 - 2.5e-06 28.0 1.5 1.1e-05 25.9 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 GBG81474.1 - 3.1e-06 27.2 0.0 1.8e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GBG81474.1 - 2.5e-05 24.5 0.0 8.9e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GBG81474.1 - 0.00018 22.1 0.0 0.0036 17.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GBG81474.1 - 0.00026 21.3 0.1 0.0094 16.2 0.2 3.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GBG81474.1 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 GBG81474.1 - 0.0023 18.1 0.0 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain V-SNARE PF05008.15 GBG81474.1 - 0.0043 17.4 4.4 0.017 15.4 4.4 2.1 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus AAA_33 PF13671.6 GBG81474.1 - 0.0066 16.6 0.0 0.026 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF4349 PF14257.6 GBG81474.1 - 0.0085 15.6 1.6 0.018 14.5 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) Sigma54_activat PF00158.26 GBG81474.1 - 0.0087 15.8 0.0 0.18 11.5 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain TIP49 PF06068.13 GBG81474.1 - 0.011 14.9 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 GBG81474.1 - 0.027 13.9 0.5 0.071 12.5 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2730 PF10805.8 GBG81474.1 - 0.037 14.1 1.8 0.066 13.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) ABC_tran PF00005.27 GBG81474.1 - 0.039 14.5 0.1 0.42 11.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 GBG81474.1 - 0.041 13.9 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GBG81474.1 - 0.052 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 GBG81474.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 GBG81474.1 - 0.056 13.0 1.1 0.26 10.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.11 GBG81474.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 GBG81474.1 - 1.5 8.6 0.0 1.5 8.6 0.0 4.0 5 0 0 5 5 4 0 AAA domain TMPIT PF07851.13 GBG81474.1 - 4 6.6 5.1 6.7 5.9 3.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein Ribosomal_L10 PF00466.20 GBG81475.1 - 3e-19 69.0 0.1 4.5e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3456 PF11938.8 GBG81477.1 - 1.8e-06 28.5 0.7 2.4e-06 28.2 0.7 1.2 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP PDEase_II PF02112.15 GBG81478.1 - 0.023 13.8 0.2 0.03 13.4 0.2 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II DUF3752 PF12572.8 GBG81478.1 - 2.2 8.8 9.6 0.76 10.3 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) DUF3499 PF12005.8 GBG81478.1 - 3.5 8.3 9.0 2 9.0 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3499) HSP70 PF00012.20 GBG81479.1 - 1.1e-258 859.4 9.5 1.3e-258 859.2 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG81479.1 - 1.6e-16 60.1 0.6 1.2e-15 57.2 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG81479.1 - 0.00033 20.4 0.0 0.0032 17.2 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 GBG81479.1 - 0.0049 16.2 7.0 0.0081 15.5 7.0 1.3 1 0 0 1 1 1 1 Radial spoke protein 3 Hydantoinase_A PF01968.18 GBG81479.1 - 0.039 13.2 0.2 0.039 13.2 0.2 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase PIN_8 PF18476.1 GBG81479.1 - 0.22 11.4 7.9 0.85 9.4 0.2 2.4 2 0 0 2 2 2 0 PIN like domain RVT_1 PF00078.27 GBG81481.1 - 7.8e-28 97.5 0.1 1.1e-27 97.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81481.1 - 1.4e-27 95.7 0.0 2.8e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81481.1 - 1.2e-15 57.7 0.0 2.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_M8 PF01457.16 GBG81482.1 - 7.6e-31 107.4 0.0 1.7e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 Leishmanolysin RT_RNaseH_2 PF17919.1 GBG81482.1 - 2.5e-30 104.5 0.0 5.9e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81482.1 - 1.6e-25 89.4 0.5 3.9e-25 88.2 0.3 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81482.1 - 1.5e-18 66.6 0.0 3.4e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81482.1 - 1.5e-15 57.5 0.0 3.8e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG81482.1 - 3.6e-10 39.7 0.5 7.4e-10 38.7 0.5 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG81482.1 - 0.0023 17.6 0.0 0.0068 16.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) zf-CCHC_3 PF13917.6 GBG81482.1 - 0.0088 16.0 1.5 0.025 14.5 1.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 GBG81482.1 - 0.021 15.0 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG81482.1 - 2.1 8.6 4.8 5.3 7.3 4.8 1.8 1 0 0 1 1 1 0 Zinc knuckle Prp19 PF08606.11 GBG81483.1 - 1.2e-28 98.9 0.6 2.4e-28 97.9 0.6 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 GBG81483.1 - 5.4e-26 90.3 5.5 5.1e-06 27.1 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG81483.1 - 1.9e-09 37.7 0.0 0.071 13.4 0.0 5.4 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 GBG81483.1 - 1.8e-05 24.8 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GBG81483.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit WD40_like PF17005.5 GBG81483.1 - 0.013 14.9 0.0 0.61 9.4 0.0 2.4 1 1 1 2 2 2 0 WD40-like domain DUF5046 PF16465.5 GBG81483.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) Ge1_WD40 PF16529.5 GBG81483.1 - 0.15 11.0 0.3 2.6 6.9 0.1 3.0 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DOMON PF03351.17 GBG81484.1 - 0.0052 17.0 0.0 0.0088 16.3 0.0 1.3 1 0 0 1 1 1 1 DOMON domain CENP-K PF11802.8 GBG81485.1 - 0.01 15.5 2.8 0.023 14.3 2.8 1.5 1 1 0 1 1 1 1 Centromere-associated protein K TFIIA PF03153.13 GBG81485.1 - 0.21 11.5 12.7 0.25 11.3 12.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CREPT PF16566.5 GBG81485.1 - 0.94 9.6 10.4 2.7 8.2 1.2 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3502 PF12010.8 GBG81485.1 - 1.1 9.9 4.7 0.69 10.6 1.2 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3502) DUF4407 PF14362.6 GBG81485.1 - 5.4 6.3 27.6 49 3.1 27.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) BAH PF01426.18 GBG81486.1 - 3.2e-06 27.0 0.1 1.6e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 BAH domain SPATA1_C PF15743.5 GBG81486.1 - 0.0022 18.1 9.1 0.003 17.6 8.3 1.7 1 1 0 1 1 1 1 Spermatogenesis-associated C-terminus DUF2201_N PF13203.6 GBG81487.1 - 3.3 7.2 7.8 3.6 7.1 7.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain RT_RNaseH PF17917.1 GBG81488.1 - 2.3e-47 159.6 1.5 5.2e-30 103.8 0.2 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81488.1 - 6.6e-37 125.4 1.4 6.6e-19 67.8 0.2 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG81488.1 - 1.3e-34 118.3 0.0 1.8e-23 82.4 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Cation_ATPase_C PF00689.21 GBG81488.1 - 8.2e-33 113.6 7.8 5.6e-16 58.8 2.4 2.4 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus rve PF00665.26 GBG81488.1 - 2.8e-23 82.3 0.1 7.1e-13 48.8 0.0 3.2 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG81488.1 - 5.5e-23 81.6 0.0 1.1e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrolase PF00702.26 GBG81488.1 - 7.7e-13 49.2 0.3 6.2e-12 46.2 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Retrotrans_gag PF03732.17 GBG81488.1 - 4.4e-07 30.1 3.7 0.022 15.0 0.0 3.3 3 0 0 3 3 2 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG81488.1 - 0.00018 21.7 0.0 0.37 11.0 0.0 2.7 2 0 0 2 2 2 2 H2C2 zinc finger Hydrolase_3 PF08282.12 GBG81488.1 - 0.011 15.5 0.1 0.011 15.5 0.1 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4187 PF13821.6 GBG81488.1 - 0.15 11.9 4.0 0.14 12.0 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Cation_ATPase_C PF00689.21 GBG81489.1 - 3.4e-33 114.9 8.1 4.3e-16 59.1 2.6 2.6 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus RT_RNaseH PF17917.1 GBG81489.1 - 1.2e-30 105.9 0.2 3.4e-30 104.4 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81489.1 - 5e-24 84.2 0.0 1.2e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81489.1 - 3.9e-23 82.1 0.0 7.3e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81489.1 - 8.4e-16 57.8 0.1 1.8e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81489.1 - 1.5e-13 51.0 0.0 4.6e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Hydrolase PF00702.26 GBG81489.1 - 8.1e-11 42.6 0.0 8.1e-11 42.6 0.0 3.1 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GBG81489.1 - 0.0073 16.1 0.1 0.0073 16.1 0.1 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Retrotrans_gag PF03732.17 GBG81489.1 - 0.013 15.8 2.0 0.02 15.1 0.2 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein DUF4187 PF13821.6 GBG81489.1 - 0.019 14.7 1.0 0.093 12.5 1.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-H2C2 PF09337.10 GBG81489.1 - 0.088 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG81490.1 - 3.4e-28 98.7 0.2 3.6e-27 95.3 0.0 2.3 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81490.1 - 1.8e-13 50.4 0.0 6.1e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG81490.1 - 6e-07 30.0 0.0 1.4e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81490.1 - 7.5e-07 29.6 0.0 2.3e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81490.1 - 2.1e-05 24.3 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81490.1 - 6.5e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG81490.1 - 0.00059 20.1 0.0 0.0017 18.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG81490.1 - 0.00091 19.5 13.7 0.0027 17.9 0.1 4.2 4 0 0 4 4 3 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG81490.1 - 0.011 16.3 7.6 0.011 16.3 7.6 3.3 3 1 0 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Gp58 PF07902.11 GBG81490.1 - 0.31 9.3 3.0 0.49 8.6 3.0 1.3 1 0 0 1 1 1 0 gp58-like protein NPV_P10 PF05531.12 GBG81490.1 - 0.5 10.9 2.0 20 5.7 0.0 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 GBG81490.1 - 2.9 8.3 12.4 0.067 13.5 3.6 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cation_ATPase PF13246.6 GBG81491.1 - 9.3e-09 35.3 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GBG81491.1 - 1.6e-05 24.5 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 GBG81492.1 - 5.8e-09 35.9 0.0 9.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Cation transport ATPase (P-type) rve PF00665.26 GBG81493.1 - 2.9e-08 33.9 0.0 9.4e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG81493.1 - 0.00024 20.7 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG81493.1 - 0.066 13.0 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain DUF169 PF02596.15 GBG81493.1 - 0.23 11.4 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 PIEZO PF15917.5 GBG81494.1 - 0.92 8.9 10.3 1 8.8 10.3 1.2 1 0 0 1 1 1 0 Piezo PA26 PF04636.13 GBG81494.1 - 4.6 6.0 8.4 4.9 6.0 8.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3807 PF12720.7 GBG81494.1 - 4.9 7.4 15.1 6.2 7.0 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RT_RNaseH_2 PF17919.1 GBG81495.1 - 3e-23 81.7 0.0 1.1e-22 79.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81495.1 - 9.7e-22 77.2 0.0 3.4e-21 75.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81495.1 - 6.7e-19 68.3 1.9 1.2e-18 67.5 0.0 2.4 3 1 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81495.1 - 1.1e-16 60.6 0.7 2.7e-16 59.4 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG81495.1 - 3.2e-08 34.0 0.0 1e-07 32.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81495.1 - 3.4e-08 34.0 0.0 1e-07 32.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81495.1 - 3.2e-06 27.0 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG81495.1 - 0.00017 21.8 8.3 0.064 13.5 0.1 5.0 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG81495.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease FlxA PF14282.6 GBG81495.1 - 0.021 14.8 0.3 0.021 14.8 0.3 3.6 4 0 0 4 4 3 0 FlxA-like protein APG6_N PF17675.1 GBG81495.1 - 0.039 14.5 5.6 0.25 11.9 0.0 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-H2C2 PF09337.10 GBG81495.1 - 0.05 13.8 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger SlyX PF04102.12 GBG81495.1 - 2.6 8.7 15.3 1.4 9.6 0.1 4.4 4 0 0 4 4 3 0 SlyX CLZ PF16526.5 GBG81495.1 - 7.5 7.0 5.9 42 4.6 0.3 3.8 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cation_ATPase_N PF00690.26 GBG81496.1 - 4.9e-10 39.0 0.0 8.7e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 GBG81496.1 - 1.2e-07 31.4 0.1 1.2e-07 31.4 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase DUF3093 PF11292.8 GBG81496.1 - 0.13 12.5 1.7 0.58 10.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) PBP PF01161.20 GBG81498.1 - 2e-05 24.9 0.0 2.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DDE_Tnp_4 PF13359.6 GBG81499.1 - 2.1e-11 43.8 0.0 3.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81499.1 - 2.2e-06 27.4 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DUF5320 PF17253.2 GBG81500.1 - 1.4 10.0 8.5 0.39 11.8 4.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) RT_RNaseH_2 PF17919.1 GBG81504.1 - 5e-25 87.5 0.0 8.5e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81504.1 - 8.5e-23 80.6 0.0 1.5e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG81504.1 - 0.042 13.3 47.5 0.058 12.8 47.5 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG81504.1 - 0.07 11.7 42.2 0.1 11.2 42.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 GBG81504.1 - 0.26 9.4 44.9 0.37 8.9 44.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG81504.1 - 0.93 8.8 42.0 1.7 7.9 42.0 1.4 1 0 0 1 1 1 0 BUD22 DDHD PF02862.17 GBG81504.1 - 2.4 8.3 7.6 4.5 7.4 7.6 1.4 1 0 0 1 1 1 0 DDHD domain Cwf_Cwc_15 PF04889.12 GBG81504.1 - 3.6 7.2 41.2 6.3 6.5 41.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SpoIIIAH PF12685.7 GBG81504.1 - 4.9 6.9 19.7 9.1 6.0 19.7 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Presenilin PF01080.17 GBG81504.1 - 7.9 5.1 23.3 12 4.5 23.3 1.3 1 0 0 1 1 1 0 Presenilin zf-CCHC PF00098.23 GBG81506.1 - 3e-05 23.9 1.3 6.4e-05 22.8 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle BBS1 PF14779.6 GBG81506.1 - 0.0076 15.7 2.4 0.011 15.2 2.4 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 FKBP_C PF00254.28 GBG81507.1 - 1.1e-23 83.4 0.0 5.8e-11 42.6 0.0 4.0 4 0 0 4 4 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 GBG81507.1 - 2.4e-13 49.1 0.3 3.1e-06 26.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG81507.1 - 9.3e-11 41.1 0.5 2.1e-05 24.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG81507.1 - 2.1e-05 24.6 0.0 0.00022 21.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GBG81507.1 - 9.5e-05 22.3 0.6 0.0007 19.6 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG81507.1 - 0.0016 18.1 0.2 0.064 13.0 0.2 3.0 2 1 1 3 3 3 1 TPR repeat DUF508 PF04370.12 GBG81507.1 - 0.0026 17.5 0.1 0.0026 17.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF508) TPR_12 PF13424.6 GBG81507.1 - 0.0081 16.4 0.1 0.22 11.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG81507.1 - 0.0081 16.6 0.1 0.02 15.4 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG81507.1 - 0.01 16.5 0.0 0.37 11.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG81507.1 - 0.015 15.9 0.2 20 6.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG81507.1 - 0.022 15.1 0.0 0.087 13.2 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG81507.1 - 0.026 15.3 0.0 0.49 11.4 0.0 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat 7kD_DNA_binding PF02294.18 GBG81507.1 - 0.045 13.8 0.0 0.19 11.8 0.0 2.1 1 0 0 1 1 1 0 7kD DNA-binding domain PRIMA1 PF16101.5 GBG81507.1 - 0.18 11.8 3.9 5.7 7.0 2.1 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG81507.1 - 8.8 5.7 11.6 0.92 8.9 3.3 2.6 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal TMEM247 PF15444.6 GBG81509.1 - 0.17 11.9 3.7 0.4 10.7 3.7 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 CPDase PF07823.11 GBG81510.1 - 1.5e-21 77.0 0.0 1.8e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 GBG81510.1 - 1.6e-08 34.6 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 GBG81510.1 - 0.0026 17.9 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 2 LigT like Phosphoesterase DUF1045 PF06299.12 GBG81510.1 - 0.033 14.2 0.1 3.8 7.4 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1045) Glyco_transf_28 PF03033.20 GBG81511.1 - 0.0023 18.0 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GBG81511.1 - 0.054 12.3 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GBG81511.1 - 0.17 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain RT_RNaseH_2 PF17919.1 GBG81512.1 - 1.2e-19 70.2 0.0 2.9e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81512.1 - 1.3e-16 60.7 0.0 2.9e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81512.1 - 1.9e-16 59.9 0.2 3.9e-16 58.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG81512.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81512.1 - 0.00047 20.7 0.0 0.00098 19.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81512.1 - 0.00084 19.9 0.0 0.0019 18.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81512.1 - 0.095 12.5 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG81512.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG81512.1 - 0.14 11.7 0.1 0.65 9.5 0.0 1.9 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG81513.1 - 1.4e-22 80.3 0.1 2.5e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG81513.1 - 6.8e-08 33.0 0.1 2.5e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81513.1 - 2.2e-07 31.4 0.0 5.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81513.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81513.1 - 0.00011 22.0 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1664 PF07889.12 GBG81513.1 - 0.15 12.1 0.4 0.53 10.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Methyltransf_21 PF05050.12 GBG81514.1 - 2.8e-12 47.0 0.0 6.3e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase FkbM domain GRP PF07172.11 GBG81516.1 - 5.6 7.7 14.5 17 6.2 14.5 1.8 1 0 0 1 1 1 0 Glycine rich protein family rve PF00665.26 GBG81517.1 - 8.6e-08 32.4 0.0 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81517.1 - 0.00062 20.3 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81517.1 - 0.0058 17.2 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ICA69 PF04629.14 GBG81517.1 - 0.64 10.3 10.5 1.1 9.6 10.5 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain DDE_Tnp_4 PF13359.6 GBG81518.1 - 1.1e-20 73.9 0.0 1.8e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81518.1 - 5.3e-12 45.8 0.0 1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein RVT_1 PF00078.27 GBG81519.1 - 5.2e-26 91.5 0.0 7.5e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81519.1 - 1.2e-05 25.4 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG81520.1 - 0.075 12.9 0.2 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Nucleic_acid_bd PF13820.6 GBG81521.1 - 0.0042 16.9 0.0 0.46 10.3 0.1 2.5 2 0 0 2 2 2 2 Putative nucleic acid-binding region Nop53 PF07767.11 GBG81521.1 - 0.73 9.2 29.2 1.1 8.5 29.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Myc_N PF01056.18 GBG81521.1 - 0.73 9.7 10.5 1.1 9.0 10.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region RT_RNaseH_2 PF17919.1 GBG81522.1 - 1.7e-27 95.4 0.0 2.9e-13 49.7 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81522.1 - 3.3e-26 91.6 0.0 1.1e-25 89.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG81522.1 - 3.4e-10 39.7 0.2 9.6e-10 38.2 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG81522.1 - 1.1e-08 34.9 0.0 0.0039 16.7 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG81522.1 - 0.063 13.2 0.5 11 6.0 0.1 3.2 3 0 0 3 3 3 0 Ribosomal protein L34 DUF659 PF04937.15 GBG81523.1 - 6.6e-10 39.0 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG81523.1 - 0.33 11.0 1.7 0.82 9.7 1.7 1.7 1 1 0 1 1 1 0 BED zinc finger PHD PF00628.29 GBG81524.1 - 0.00036 20.3 4.3 0.00036 20.3 4.3 2.3 2 0 0 2 2 2 1 PHD-finger Mob_synth_C PF06463.13 GBG81524.1 - 0.051 13.5 0.2 0.15 12.0 0.2 1.8 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C HAUS4 PF14735.6 GBG81524.1 - 0.092 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Zf_RING PF16744.5 GBG81524.1 - 0.17 12.0 5.2 0.63 10.2 5.2 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 GBG81524.1 - 7.3 6.6 15.3 0.038 13.9 5.2 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 GBG81525.1 - 0.00035 20.4 4.3 0.00035 20.4 4.3 2.3 2 0 0 2 2 2 1 PHD-finger Mob_synth_C PF06463.13 GBG81525.1 - 0.049 13.6 0.2 0.15 12.0 0.2 1.8 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C HAUS4 PF14735.6 GBG81525.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Zf_RING PF16744.5 GBG81525.1 - 0.17 12.0 5.2 0.62 10.2 5.2 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger Histone PF00125.24 GBG81526.1 - 9.3e-26 90.7 0.4 9.3e-26 90.7 0.4 4.3 5 0 0 5 5 5 1 Core histone H2A/H2B/H3/H4 RVT_1 PF00078.27 GBG81527.1 - 1.8e-30 106.1 0.0 3e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81527.1 - 9.8e-08 32.2 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Kinesin PF00225.23 GBG81528.1 - 2.1e-62 211.0 0.0 3.2e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG81528.1 - 2.3e-06 27.6 0.0 7.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding AMP-binding PF00501.28 GBG81530.1 - 4e-83 279.4 0.1 2.6e-81 273.4 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GBG81530.1 - 1.3e-19 69.8 2.5 3.1e-19 68.6 2.5 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 GBG81530.1 - 2.6e-15 57.1 0.0 5.3e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HATPase_c PF02518.26 GBG81531.1 - 0.047 14.2 0.2 0.092 13.3 0.2 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Es2 PF09751.9 GBG81533.1 - 0.014 15.2 19.3 0.02 14.7 19.3 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 RT_RNaseH PF17917.1 GBG81534.1 - 8.3e-28 96.7 0.1 1.9e-27 95.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81534.1 - 7.4e-27 93.3 0.0 2.1e-26 91.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81534.1 - 2.7e-18 65.8 0.3 2.7e-18 65.8 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain DUF3863 PF12979.7 GBG81534.1 - 0.028 13.3 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) zf-H2C2 PF09337.10 GBG81534.1 - 0.09 13.0 0.2 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 H2C2 zinc finger RVT_1 PF00078.27 GBG81535.1 - 2.8e-32 112.0 0.0 4.4e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81535.1 - 1.2e-14 54.1 0.1 5.8e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase LCAT PF02450.15 GBG81535.1 - 7.3e-13 48.4 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase RT_RNaseH PF17917.1 GBG81535.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_4 PF14392.6 GBG81535.1 - 0.17 11.7 0.1 0.46 10.3 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle TolA_bind_tri PF16331.5 GBG81535.1 - 7.3 6.7 7.4 0.73 10.0 2.4 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF659 PF04937.15 GBG81536.1 - 2.7e-13 50.0 0.0 4.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Rep_4 PF05797.11 GBG81536.1 - 0.048 12.8 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Presenilin PF01080.17 GBG81536.1 - 5.9 5.5 6.2 7.7 5.2 6.2 1.1 1 0 0 1 1 1 0 Presenilin DUF16 PF01519.16 GBG81537.1 - 0.012 16.1 1.1 0.33 11.5 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF16 Cast PF10174.9 GBG81537.1 - 0.049 11.9 1.0 0.086 11.1 1.0 1.3 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone TRPM_tetra PF16519.5 GBG81537.1 - 0.13 12.4 0.7 5.2 7.3 0.0 2.7 3 0 0 3 3 3 0 Tetramerisation domain of TRPM TMF_DNA_bd PF12329.8 GBG81537.1 - 0.44 10.6 2.3 0.55 10.3 0.1 2.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 GBG81537.1 - 0.57 10.8 9.5 0.41 11.3 1.5 3.5 2 1 1 3 3 3 0 SlyX TolA_bind_tri PF16331.5 GBG81537.1 - 1.5 9.0 8.7 2.7 8.1 5.5 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF3947 PF13135.6 GBG81537.1 - 6 7.1 7.1 8.3 6.7 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3947) RVT_1 PF00078.27 GBG81538.1 - 2.9e-10 40.1 0.1 3.8e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81538.1 - 4.8e-10 39.4 0.0 9.8e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81538.1 - 0.0008 19.7 0.0 0.0019 18.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG81538.1 - 0.091 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG81539.1 - 5.9e-25 87.2 0.0 1.3e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81539.1 - 4.7e-23 81.5 0.0 3.8e-22 78.6 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81539.1 - 1.3e-14 54.4 0.0 3.3e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG81539.1 - 6.4e-13 48.6 0.1 2.4e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 GBG81539.1 - 0.00033 20.4 0.0 0.0012 18.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG81539.1 - 0.0014 18.9 2.3 0.018 15.3 0.1 3.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG81539.1 - 0.0087 15.9 0.6 0.0087 15.9 0.6 1.7 2 0 0 2 2 2 1 Zinc knuckle RVP PF00077.20 GBG81539.1 - 0.028 14.7 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Phospholip_B PF04916.13 GBG81539.1 - 0.047 12.3 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase B zf-CCHC PF00098.23 GBG81539.1 - 0.058 13.5 1.8 0.13 12.4 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle PBS_linker_poly PF00427.21 GBG81539.1 - 0.16 12.0 0.1 0.41 10.7 0.1 1.6 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide RVT_1 PF00078.27 GBG81540.1 - 4.1e-07 29.7 0.0 0.011 15.3 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG81540.1 - 6.2e-05 22.7 7.0 0.036 13.9 0.9 2.4 2 0 0 2 2 2 2 Zinc knuckle RT_RNaseH PF17917.1 GBG81540.1 - 0.0071 16.6 0.0 0.044 14.1 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG81540.1 - 0.019 15.0 9.0 1 9.6 0.8 2.6 2 0 0 2 2 2 0 Zinc knuckle eIF-1a PF01176.19 GBG81540.1 - 0.15 11.9 0.1 0.42 10.5 0.1 1.7 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 RT_RNaseH_2 PF17919.1 GBG81540.1 - 0.18 11.8 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-CCHC_6 PF15288.6 GBG81540.1 - 0.63 9.9 6.9 7.5 6.5 0.7 2.8 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG81541.1 - 7.9e-28 96.4 0.0 2.1e-27 95.1 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81541.1 - 2.2e-16 60.0 0.0 5.4e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81541.1 - 2.2e-13 50.3 0.1 3.5e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81543.1 - 3.5e-08 33.6 0.0 7.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_5 PF14787.6 GBG81543.1 - 0.38 10.5 4.1 0.99 9.2 4.1 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG81543.1 - 0.76 10.0 4.7 2 8.7 4.7 1.8 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG81544.1 - 9.6e-21 74.0 0.0 1.9e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81544.1 - 1.1e-20 73.5 0.0 2.7e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81544.1 - 1.3e-15 57.2 0.1 3.4e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG81544.1 - 3.6e-08 33.9 0.0 8.9e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG81544.1 - 9.2e-07 29.1 0.0 2.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG81544.1 - 2.3e-06 28.1 0.0 6.2e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG81544.1 - 0.00091 19.4 0.1 0.002 18.3 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG81544.1 - 0.0061 16.4 0.3 0.013 15.3 0.3 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG81544.1 - 0.062 13.6 0.0 0.21 11.9 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease Ribosomal_60s PF00428.19 GBG81544.1 - 1.2 9.7 5.1 6.5 7.4 5.1 2.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Asp_protease_2 PF13650.6 GBG81545.1 - 1.8e-06 28.5 0.1 4.2e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81545.1 - 1.1e-05 25.9 0.4 2.8e-05 24.6 0.4 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG81545.1 - 0.0008 19.5 0.2 0.0018 18.3 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-FCS PF06467.14 GBG81545.1 - 0.057 13.4 0.6 0.14 12.1 0.6 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF4911 PF16256.5 GBG81545.1 - 0.11 12.4 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) RVP PF00077.20 GBG81545.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG81545.1 - 0.47 10.6 3.3 1.3 9.2 3.3 1.7 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG81546.1 - 3e-25 88.2 0.0 5.1e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81546.1 - 2.4e-22 79.2 0.0 5e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81546.1 - 2.2e-13 50.1 0.0 6.7e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain UBA_4 PF14555.6 GBG81547.1 - 1.7e-12 46.9 0.0 3.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 GBG81547.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like SUB1_ProdP9 PF18213.1 GBG81547.1 - 0.16 11.9 0.3 4.1 7.3 0.1 2.2 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 CSN8_PSD8_EIF3K PF10075.9 GBG81547.1 - 0.22 11.5 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Ntox33 PF15533.6 GBG81547.1 - 2 9.0 3.9 1.7 9.2 0.1 2.3 1 1 1 2 2 2 0 Bacterial toxin 33 DUF1949 PF09186.11 GBG81548.1 - 0.034 14.0 0.3 0.25 11.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) DUF5401 PF17380.2 GBG81548.1 - 0.5 8.4 19.7 0.51 8.4 19.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) FtsK_SpoIIIE PF01580.18 GBG81548.1 - 1.5 8.1 5.5 1.4 8.2 1.7 2.0 1 1 1 2 2 2 0 FtsK/SpoIIIE family PA26 PF04636.13 GBG81548.1 - 3.6 6.4 8.6 4.1 6.2 8.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SURF2 PF05477.11 GBG81548.1 - 7.4 6.2 15.4 8.2 6.0 15.2 1.3 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RVT_1 PF00078.27 GBG81549.1 - 1.8e-35 122.5 0.2 1.7e-30 106.2 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81549.1 - 1.6e-21 76.2 0.0 5.4e-21 74.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG81549.1 - 1.3e-11 44.4 0.0 8e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG81549.1 - 1.6e-11 44.4 0.0 4.1e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG81549.1 - 2.2e-09 37.7 0.0 7.1e-05 23.3 0.0 3.1 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81549.1 - 6.6e-09 36.3 0.0 0.00011 22.7 0.0 3.0 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.10 GBG81549.1 - 0.00016 21.4 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease DUF1758 PF05585.12 GBG81549.1 - 0.001 18.9 0.1 0.0052 16.6 0.0 2.2 2 0 0 2 2 2 1 Putative peptidase (DUF1758) RVP PF00077.20 GBG81549.1 - 0.015 15.6 0.0 12 6.2 0.0 2.9 2 1 0 2 2 2 0 Retroviral aspartyl protease Peptidase_M9 PF01752.17 GBG81549.1 - 0.54 9.4 4.2 0.19 10.9 0.1 2.3 2 0 0 2 2 2 0 Collagenase RT_RNaseH_2 PF17919.1 GBG81550.1 - 5.8e-32 109.7 0.0 5.9e-31 106.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81550.1 - 1.9e-31 108.5 0.2 2.8e-30 104.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81550.1 - 6.5e-20 71.0 0.7 1.4e-19 69.9 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81550.1 - 8.6e-18 64.7 0.0 2.8e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG81550.1 - 3.4e-13 49.6 0.1 3.7e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG81550.1 - 0.00018 22.1 0.0 0.00039 21.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81550.1 - 0.00039 20.2 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG81550.1 - 0.00063 20.3 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG81550.1 - 0.00067 19.8 0.1 0.0024 18.1 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG81550.1 - 0.0027 17.5 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) LcrG PF07216.12 GBG81550.1 - 0.079 12.9 0.2 0.19 11.6 0.2 1.7 1 0 0 1 1 1 0 LcrG protein Phage_GPO PF05929.11 GBG81550.1 - 0.24 11.0 0.0 0.47 10.0 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF716 PF04819.12 GBG81551.1 - 0.013 15.2 0.4 0.016 14.8 0.4 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF716) U-box PF04564.15 GBG81555.1 - 1.9e-12 47.2 0.0 4.5e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 U-box domain Arm PF00514.23 GBG81555.1 - 3.3e-07 30.1 14.7 1.6 8.9 0.0 8.8 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 GBG81555.1 - 0.014 15.4 0.1 0.07 13.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) KAP PF05804.12 GBG81555.1 - 0.028 12.6 0.3 0.13 10.4 0.1 2.0 1 1 0 1 1 1 0 Kinesin-associated protein (KAP) zf-Nse PF11789.8 GBG81555.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HEAT_EZ PF13513.6 GBG81555.1 - 0.24 12.0 14.0 3.8 8.1 0.0 6.2 6 0 0 6 6 6 0 HEAT-like repeat RT_RNaseH_2 PF17919.1 GBG81556.1 - 1.7e-31 108.2 0.0 3.6e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81556.1 - 3.4e-28 98.0 0.3 6.7e-28 97.0 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81556.1 - 3e-18 65.6 0.0 7.3e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81556.1 - 1.7e-11 44.3 0.0 4.2e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG81556.1 - 0.0057 16.4 1.7 0.015 15.0 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG81556.1 - 0.0061 16.7 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Peptidase_M4_C PF02868.15 GBG81556.1 - 0.081 12.8 0.4 0.47 10.3 0.0 2.2 3 0 0 3 3 3 0 Thermolysin metallopeptidase, alpha-helical domain Clr5 PF14420.6 GBG81556.1 - 0.094 13.0 0.7 3.3 8.0 0.5 3.0 2 0 0 2 2 2 0 Clr5 domain Asp_protease_2 PF13650.6 GBG81558.1 - 3.3e-07 30.8 0.0 6.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81558.1 - 2.1e-06 28.2 0.0 4.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81558.1 - 7.8e-05 22.5 0.0 0.00037 20.3 0.0 2.1 2 1 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81558.1 - 0.00031 20.5 0.0 0.00052 19.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG81558.1 - 0.0011 18.5 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81559.1 - 4.1e-20 71.7 0.1 8.7e-20 70.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG81559.1 - 4.7e-13 49.2 1.1 4.3e-11 42.8 0.0 3.3 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81559.1 - 5.7e-12 45.9 0.1 1.5e-11 44.5 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG81559.1 - 1.7e-07 31.1 0.0 3.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81559.1 - 1e-06 29.2 0.0 2.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81559.1 - 1.9e-05 25.1 0.0 4.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG81559.1 - 0.0018 18.2 0.0 0.0054 16.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SlyX PF04102.12 GBG81559.1 - 0.0035 17.9 3.5 0.052 14.2 0.2 3.1 2 0 0 2 2 2 1 SlyX Asp_protease PF09668.10 GBG81559.1 - 0.0071 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG81559.1 - 0.01 15.0 0.7 0.14 11.3 0.0 2.5 2 1 1 3 3 3 0 Autophagy protein Apg17 zf-H2C2 PF09337.10 GBG81559.1 - 0.073 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger HAUS-augmin3 PF14932.6 GBG81559.1 - 0.15 11.6 2.2 0.27 10.8 2.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ADIP PF11559.8 GBG81559.1 - 0.19 11.8 3.5 1.4 9.0 0.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 GBG81559.1 - 0.44 10.6 1.9 2.7 8.0 1.6 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 GBG81559.1 - 1.1 9.5 5.5 2.2 8.5 5.5 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Trimer_CC PF08954.11 GBG81559.1 - 1.9 8.1 3.5 2.7 7.6 0.5 2.8 1 1 1 2 2 2 0 Trimerisation motif CLZ PF16526.5 GBG81559.1 - 1.9 8.9 4.1 0.83 10.1 0.3 2.4 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels C1_2 PF03107.16 GBG81560.1 - 0.27 11.6 0.1 0.27 11.6 0.1 3.1 3 1 1 4 4 4 0 C1 domain RT_RNaseH_2 PF17919.1 GBG81561.1 - 1.8e-31 108.1 0.0 3.7e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81561.1 - 6.9e-30 103.4 0.0 1.4e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81561.1 - 6.9e-06 25.7 0.2 1.4e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Yop-YscD_ppl PF16693.5 GBG81561.1 - 0.065 12.7 0.0 6.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Inner membrane component of T3SS, periplasmic domain KinB_sensor PF16767.5 GBG81561.1 - 0.14 12.6 0.1 1.2 9.6 0.1 2.1 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Presenilin PF01080.17 GBG81562.1 - 9 4.9 38.3 10 4.7 38.3 1.0 1 0 0 1 1 1 0 Presenilin RcnB PF11776.8 GBG81563.1 - 0.003 17.6 0.0 7.9 6.6 0.0 3.7 3 0 0 3 3 3 2 Nickel/cobalt transporter regulator Rx_N PF18052.1 GBG81563.1 - 0.027 14.7 0.2 0.18 12.1 0.0 2.2 1 1 0 2 2 2 0 Rx N-terminal domain MFS_1 PF07690.16 GBG81564.1 - 8.7e-52 176.2 24.6 5.4e-34 117.7 12.3 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 GBG81564.1 - 1.4e-07 31.1 2.6 1.4e-07 31.1 2.6 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 GBG81564.1 - 0.00023 20.2 6.0 0.00023 20.2 6.0 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 GBG81564.1 - 0.0093 14.2 0.7 0.3 9.3 0.1 2.2 2 0 0 2 2 2 2 BT1 family eIF-1a PF01176.19 GBG81564.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 DUF2385 PF09539.10 GBG81564.1 - 0.092 13.3 0.1 1.4 9.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Tyrosinase PF00264.20 GBG81568.1 - 7.4e-31 108.2 10.0 2.6e-17 63.9 0.1 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG81568.1 - 6.1e-17 61.1 0.7 1.9e-16 59.5 0.7 1.9 1 0 0 1 1 1 1 Polyphenol oxidase middle domain Chromo PF00385.24 GBG81569.1 - 3.5e-12 46.0 0.0 6.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG81569.1 - 2.2e-10 40.8 0.4 5.1e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Arm PF00514.23 GBG81571.1 - 0.0062 16.5 0.1 1.2 9.3 0.1 3.1 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GBG81571.1 - 0.03 14.6 3.4 0.092 13.1 0.1 3.5 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 GBG81571.1 - 0.045 14.1 2.2 12 6.3 0.0 4.1 4 1 0 4 4 4 0 HEAT repeats Surfac_D-trimer PF09006.11 GBG81571.1 - 0.1 12.5 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation HEAT_EZ PF13513.6 GBG81571.1 - 0.11 13.1 1.9 2.9 8.5 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat DUF2517 PF10725.9 GBG81571.1 - 0.16 11.7 0.4 0.46 10.3 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) MbeD_MobD PF04899.12 GBG81572.1 - 7.7 6.7 10.3 1.8 8.8 2.9 3.0 2 1 1 3 3 3 0 MbeD/MobD like RT_RNaseH_2 PF17919.1 GBG81573.1 - 2.9e-31 107.5 0.0 5.6e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81573.1 - 2.4e-29 101.7 0.0 4.5e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81573.1 - 1.6e-22 80.1 0.0 2.8e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81573.1 - 5.6e-18 64.8 0.2 1e-17 63.9 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain ANAPC4_WD40 PF12894.7 GBG81574.1 - 0.083 13.2 0.0 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GBG81574.1 - 0.11 13.4 11.2 48 5.1 0.0 5.5 5 1 0 5 5 5 0 WD domain, G-beta repeat WD40 PF00400.32 GBG81575.1 - 4.5e-11 43.1 5.0 0.048 14.6 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 GBG81575.1 - 0.0048 15.6 0.0 2.9 6.4 0.0 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 WD40 PF00400.32 GBG81576.1 - 1e-07 32.5 1.9 1.9 9.5 0.3 5.2 5 1 0 5 5 5 3 WD domain, G-beta repeat RVT_1 PF00078.27 GBG81577.1 - 4.5e-58 196.4 0.3 1.7e-31 109.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81577.1 - 3.6e-31 107.2 0.0 8.8e-31 105.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81577.1 - 2.3e-28 98.6 0.1 4.4e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG81577.1 - 3.3e-06 27.6 0.0 7.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81577.1 - 6e-05 23.6 0.0 0.00013 22.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG81577.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Retrotrans_gag PF03732.17 GBG81577.1 - 0.026 14.8 0.0 0.15 12.4 0.0 2.4 1 0 0 1 1 1 0 Retrotransposon gag protein NUDIX PF00293.28 GBG81577.1 - 0.03 14.4 0.2 27 4.8 0.0 3.5 3 0 0 3 3 3 0 NUDIX domain Asp_protease PF09668.10 GBG81577.1 - 0.07 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF5095 PF17016.5 GBG81577.1 - 0.12 12.0 0.4 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) HTH_24 PF13412.6 GBG81577.1 - 0.75 9.4 3.0 22 4.7 0.4 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF659 PF04937.15 GBG81579.1 - 2.1e-10 40.6 0.0 3.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81579.1 - 0.02 14.7 0.1 0.038 13.8 0.1 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Glutaredoxin PF00462.24 GBG81580.1 - 5.1e-17 61.8 0.0 9.4e-17 61.0 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_3 PF13192.6 GBG81580.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.6 GBG81580.1 - 0.05 14.0 0.1 0.081 13.4 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 GBG81580.1 - 0.088 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 GBG81580.1 - 0.12 12.6 0.2 0.19 11.9 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like F-box PF00646.33 GBG81581.1 - 9.7e-06 25.3 5.0 1.6e-05 24.7 0.1 3.0 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 GBG81581.1 - 4.7e-05 23.2 0.3 4.7e-05 23.2 0.3 2.2 2 0 0 2 2 2 1 F-box-like Mor PF08765.11 GBG81581.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Mor transcription activator family LRR_4 PF12799.7 GBG81581.1 - 1.4 9.5 3.9 4.1 8.0 0.2 3.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) MT0933_antitox PF14013.6 GBG81582.1 - 0.021 15.1 0.2 0.042 14.1 0.2 1.5 1 0 0 1 1 1 0 MT0933-like antitoxin protein RVT_1 PF00078.27 GBG81586.1 - 5.2e-29 101.3 0.1 8e-29 100.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81586.1 - 1e-07 32.2 0.0 3.3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG81586.1 - 0.0012 18.7 0.0 0.0033 17.3 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG81586.1 - 0.012 16.3 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG81589.1 - 9.9e-27 92.9 0.0 1.6e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81589.1 - 2.8e-24 85.4 0.0 4.5e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Beta_helix PF13229.6 GBG81590.1 - 3.5e-06 27.0 1.3 6.9e-05 22.7 1.2 2.1 1 1 0 1 1 1 1 Right handed beta helix region DUF5123 PF17161.4 GBG81590.1 - 0.14 13.2 0.1 8.9 7.4 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5123) Chlam_PMP PF02415.17 GBG81590.1 - 0.66 10.6 15.3 3.5 8.3 0.1 5.3 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Choline_transpo PF04515.12 GBG81595.1 - 3e-59 200.9 19.4 3e-59 200.9 19.4 1.8 2 0 0 2 2 2 1 Plasma-membrane choline transporter ATPase_gene1 PF09527.10 GBG81595.1 - 0.045 13.9 0.6 0.045 13.9 0.6 4.3 5 0 0 5 5 5 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF5353 PF17304.2 GBG81595.1 - 0.078 12.7 5.0 0.11 12.3 0.8 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5353) Disulph_isomer PF06491.11 GBG81596.1 - 0.0087 16.2 0.9 0.022 14.9 0.9 1.7 1 0 0 1 1 1 1 Disulphide isomerase YqcI_YcgG PF08892.11 GBG81596.1 - 0.012 15.5 1.2 0.027 14.3 0.1 2.0 2 0 0 2 2 2 0 YqcI/YcgG family Bcr-Abl_Oligo PF09036.10 GBG81596.1 - 0.67 10.0 7.0 0.64 10.1 1.2 2.8 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Ank_2 PF12796.7 GBG81597.1 - 5.4e-27 94.2 1.0 1.3e-11 44.9 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GBG81597.1 - 5.9e-21 74.3 1.1 0.00031 21.0 0.1 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 GBG81597.1 - 6e-17 61.8 5.3 0.0042 17.6 0.1 5.4 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG81597.1 - 3.5e-15 54.6 0.2 0.27 11.9 0.0 7.2 7 0 0 7 7 6 4 Ankyrin repeat Ank PF00023.30 GBG81597.1 - 2.6e-13 49.7 3.6 0.089 13.3 0.1 6.8 6 0 0 6 6 6 3 Ankyrin repeat RRM_1 PF00076.22 GBG81597.1 - 2.6e-10 40.0 0.2 7.1e-10 38.6 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OST-HTH PF12872.7 GBG81597.1 - 7.6e-10 38.5 0.0 2.8e-09 36.7 0.0 2.0 1 0 0 1 1 1 1 OST-HTH/LOTUS domain zf-CCCH PF00642.24 GBG81597.1 - 1.6e-05 24.6 2.3 4.4e-05 23.3 2.3 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG81597.1 - 0.0045 17.0 2.9 0.012 15.6 2.9 1.8 1 0 0 1 1 1 1 Zinc finger domain RRM_7 PF16367.5 GBG81597.1 - 0.0046 17.0 0.1 0.012 15.7 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif zf-CCCH_4 PF18044.1 GBG81597.1 - 0.018 14.8 2.6 0.047 13.5 2.6 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GBG81597.1 - 0.19 12.3 0.8 0.49 11.0 0.8 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RXT2_N PF08595.11 GBG81598.1 - 0.00031 20.8 1.8 0.00047 20.2 1.8 1.2 1 0 0 1 1 1 1 RXT2-like, N-terminal MAM33 PF02330.16 GBG81598.1 - 0.00058 19.9 0.3 0.00058 19.9 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein CDC45 PF02724.14 GBG81598.1 - 0.0055 15.1 8.5 0.0059 15.0 8.5 1.0 1 0 0 1 1 1 1 CDC45-like protein PBP1_TM PF14812.6 GBG81598.1 - 0.0059 17.0 7.3 0.0059 17.0 7.3 2.2 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal GRP PF07172.11 GBG81598.1 - 0.0069 17.0 29.5 0.014 16.1 29.5 1.5 1 1 0 1 1 1 1 Glycine rich protein family DNA_pol_phi PF04931.13 GBG81598.1 - 0.0088 14.2 11.4 0.0081 14.3 11.4 1.0 1 0 0 1 1 1 1 DNA polymerase phi CobT PF06213.12 GBG81598.1 - 0.011 15.1 6.7 0.012 15.0 6.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BSP_II PF05432.11 GBG81598.1 - 0.022 14.4 15.9 0.022 14.5 15.9 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 GBG81598.1 - 0.032 12.5 7.7 0.036 12.3 7.7 1.2 1 0 0 1 1 1 0 Nop14-like family TFB6 PF17110.5 GBG81598.1 - 0.042 13.6 0.7 0.045 13.5 0.7 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 GBG81598.1 - 0.046 13.1 12.5 0.071 12.4 12.5 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 GBG81598.1 - 0.19 10.9 15.9 0.29 10.2 15.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SGT1 PF07093.11 GBG81598.1 - 0.25 9.7 2.4 0.28 9.6 2.4 1.0 1 0 0 1 1 1 0 SGT1 protein Voldacs PF03517.13 GBG81598.1 - 0.25 11.4 6.8 0.36 10.9 6.8 1.2 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Pox_Ag35 PF03286.14 GBG81598.1 - 0.27 11.0 6.2 0.44 10.3 6.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SspB PF04386.13 GBG81598.1 - 0.3 11.0 3.3 0.49 10.3 3.3 1.4 1 1 0 1 1 1 0 Stringent starvation protein B eIF-3c_N PF05470.12 GBG81598.1 - 0.48 8.7 2.7 0.48 8.7 2.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2722 PF10846.8 GBG81598.1 - 1.4 7.8 4.0 1.9 7.4 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TRAP_alpha PF03896.16 GBG81598.1 - 1.5 7.9 3.9 2 7.5 3.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.10 GBG81598.1 - 3 8.3 19.2 5.1 7.6 19.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain S-antigen PF05756.11 GBG81598.1 - 3.2 8.2 7.9 5.6 7.4 7.9 1.5 1 0 0 1 1 1 0 S-antigen protein Myc_N PF01056.18 GBG81598.1 - 3.6 7.4 7.1 4.7 7.0 7.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RRN3 PF05327.11 GBG81598.1 - 4 5.9 6.0 4.4 5.7 6.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 GBG81598.1 - 4.6 7.1 13.2 6.7 6.5 13.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region HSP90 PF00183.18 GBG81598.1 - 4.6 6.0 6.3 6 5.6 6.3 1.1 1 0 0 1 1 1 0 Hsp90 protein Radial_spoke PF04712.12 GBG81598.1 - 4.8 6.0 10.7 6.7 5.5 10.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein FAM176 PF14851.6 GBG81598.1 - 5.3 6.7 10.6 0.26 11.0 5.3 1.5 2 0 0 2 2 2 0 FAM176 family Pes-10 PF07149.11 GBG81598.1 - 7.4 5.5 10.4 8.4 5.3 10.4 1.1 1 0 0 1 1 1 0 Pes-10 Annexin PF00191.20 GBG81599.1 - 1.1e-31 108.7 0.7 1.6e-14 53.7 0.0 4.2 4 0 0 4 4 4 4 Annexin Integrase_H2C2 PF17921.1 GBG81600.1 - 1.6e-13 50.6 0.3 4.3e-13 49.1 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG81600.1 - 0.00086 19.3 1.0 0.002 18.1 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 GBG81600.1 - 0.01 16.1 2.3 0.02 15.1 0.7 2.2 2 0 0 2 2 2 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG81601.1 - 1.8e-21 76.4 0.0 3e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81601.1 - 6.4e-19 67.8 0.0 1.2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81601.1 - 2.2e-13 50.1 0.3 5.7e-13 48.8 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG81601.1 - 2.7e-06 27.1 0.0 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG81601.1 - 0.012 15.7 1.5 0.026 14.6 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2 PF09337.10 GBG81601.1 - 0.012 15.8 0.7 0.026 14.7 0.7 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Drf_GBD PF06371.13 GBG81601.1 - 0.068 12.7 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain 2C_adapt PF08793.10 GBG81602.1 - 0.0034 17.5 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 2-cysteine adaptor domain WSK PF03832.13 GBG81603.1 - 0.035 13.8 2.0 5.4 6.8 0.1 3.0 2 0 0 2 2 2 0 WSK motif TadF PF16964.5 GBG81604.1 - 0.17 11.6 4.5 0.23 11.2 4.5 1.2 1 0 0 1 1 1 0 Putative tight adherence pilin protein F Sod_Fe_C PF02777.18 GBG81605.1 - 7.2e-34 116.0 0.0 1.5e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GBG81605.1 - 1.4e-27 95.9 2.9 2.5e-27 95.2 1.8 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RVT_1 PF00078.27 GBG81606.1 - 3.7e-11 43.0 0.1 5.1e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG81606.1 - 0.0036 17.3 4.3 0.0036 17.3 4.3 2.1 3 0 0 3 3 3 1 Zinc knuckle GEMIN8 PF15348.6 GBG81606.1 - 0.044 14.1 8.7 0.067 13.5 8.7 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 BUD22 PF09073.10 GBG81606.1 - 1.5 8.1 25.7 2 7.6 25.7 1.1 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 GBG81606.1 - 2.8 6.6 4.1 4.4 6.0 4.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.15 GBG81606.1 - 3 7.3 12.9 4.3 6.8 12.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 GBG81606.1 - 4.2 5.6 18.5 5.9 5.1 18.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG81606.1 - 6.9 6.0 22.3 10 5.4 22.3 1.2 1 0 0 1 1 1 0 SDA1 ZapB PF06005.12 GBG81607.1 - 0.00044 20.6 9.8 0.00044 20.6 9.8 3.9 3 1 1 4 4 4 2 Cell division protein ZapB Prominin PF05478.11 GBG81607.1 - 0.048 11.6 4.1 0.073 11.0 4.1 1.2 1 0 0 1 1 1 0 Prominin DUF812 PF05667.11 GBG81607.1 - 0.11 11.4 27.0 0.16 10.8 27.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Snurportin1 PF11538.8 GBG81607.1 - 8.8 6.6 9.9 1 9.6 3.8 2.7 2 0 0 2 2 2 0 Snurportin1 DUF659 PF04937.15 GBG81608.1 - 3.3e-12 46.5 0.1 6.5e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81608.1 - 0.00012 21.8 0.2 0.0004 20.1 0.2 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG81609.1 - 1.1e-12 48.0 0.0 1.5e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) IBR PF01485.21 GBG81610.1 - 5.7e-10 39.3 18.1 2.1e-09 37.4 4.7 3.6 1 1 2 3 3 3 1 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 GBG81610.1 - 0.014 15.2 17.0 0.065 13.1 3.6 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG81610.1 - 0.015 15.1 14.5 0.096 12.6 3.1 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Atrophin-1 PF03154.15 GBG81610.1 - 0.018 13.4 6.9 0.034 12.5 6.9 1.3 1 0 0 1 1 1 0 Atrophin-1 family zf-RING_5 PF14634.6 GBG81610.1 - 0.02 14.8 18.5 0.65 10.0 3.6 2.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG81610.1 - 0.027 14.5 14.0 0.19 11.8 2.6 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GBG81610.1 - 0.11 12.7 17.1 0.94 9.7 5.0 3.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GBG81610.1 - 0.12 12.7 19.6 2.4 8.6 7.8 3.1 2 0 0 2 2 2 0 Ring finger domain Zn_Tnp_IS91 PF14319.6 GBG81610.1 - 0.16 12.0 11.5 0.24 11.5 2.4 2.8 2 0 0 2 2 2 0 Transposase zinc-binding domain SLATT_1 PF18181.1 GBG81610.1 - 0.21 11.5 1.4 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 FAM27 PF15832.5 GBG81610.1 - 1.5 9.4 11.7 0.12 13.0 2.9 2.9 2 0 0 2 2 2 0 FAM27 D and E protein family Prok-RING_4 PF14447.6 GBG81610.1 - 6.4 6.7 18.8 0.58 10.1 6.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 GBG81610.1 - 7.5 6.4 13.4 18 5.2 2.5 3.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3138 PF11336.8 GBG81611.1 - 0.064 11.9 1.3 0.077 11.6 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) TssO PF17561.2 GBG81611.1 - 2.4 8.3 6.4 6.4 6.9 6.4 1.6 1 0 0 1 1 1 0 Type VI secretion system, TssO zf_CCCH_4 PF18345.1 GBG81612.1 - 5.7e-12 45.3 16.1 9.2e-06 25.5 4.4 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GBG81612.1 - 2e-10 40.2 13.7 5.6e-05 22.8 3.1 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 GBG81612.1 - 1.2e-09 37.8 11.8 1e-05 25.3 2.0 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GBG81612.1 - 4.4e-06 27.0 12.0 0.0025 18.2 1.6 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GBG81612.1 - 0.00038 21.1 12.7 0.025 15.3 0.6 3.0 2 1 1 3 3 3 2 Torus domain GyrI-like PF06445.15 GBG81613.1 - 0.029 14.7 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 GyrI-like small molecule binding domain Tim17 PF02466.19 GBG81615.1 - 2.1e-15 57.0 8.9 2.7e-15 56.7 8.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CDP-OH_P_transf PF01066.21 GBG81616.1 - 4.2e-11 43.5 0.5 4.2e-11 43.5 0.5 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RVT_1 PF00078.27 GBG81618.1 - 7.6e-26 91.0 1.0 2.6e-25 89.2 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81618.1 - 3.9e-22 78.2 0.0 7.6e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81618.1 - 1.9e-21 76.3 0.0 3.3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81618.1 - 6.7e-14 51.7 0.1 1.6e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Integrin_b_cyt PF08725.11 GBG81618.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain DDE_Tnp_4 PF13359.6 GBG81619.1 - 2.2e-14 53.5 0.6 8.3e-14 51.5 0.0 2.2 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81619.1 - 2.5e-07 30.5 0.0 4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81619.1 - 0.00042 20.0 0.1 0.00084 19.0 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG81620.1 - 2.1e-06 28.0 0.3 4.2e-06 27.1 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG81620.1 - 0.0021 18.1 0.5 0.004 17.2 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG81621.1 - 1e-23 83.3 0.0 4.4e-23 81.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81621.1 - 3.4e-23 81.9 0.0 8.4e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81621.1 - 1.3e-12 47.8 1.5 3.9e-11 42.9 0.0 3.0 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) VanY PF02557.17 GBG81621.1 - 2.4e-07 30.6 0.7 8.8e-07 28.8 0.7 2.0 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase gag-asp_proteas PF13975.6 GBG81621.1 - 0.0063 17.1 0.0 0.023 15.3 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG81621.1 - 0.012 15.8 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG81621.1 - 0.018 14.9 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG81621.1 - 0.031 14.9 0.0 0.084 13.5 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG81622.1 - 2.9e-32 110.7 0.1 7.1e-32 109.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81622.1 - 1.1e-26 93.7 0.0 1.7e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81622.1 - 1.1e-26 93.1 0.1 2.8e-26 91.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81622.1 - 5e-14 52.5 0.1 1.6e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain TLE_N PF03920.15 GBG81622.1 - 0.38 10.8 3.5 1 9.4 2.5 2.2 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain RT_RNaseH_2 PF17919.1 GBG81623.1 - 2.7e-28 97.9 0.0 5.3e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81623.1 - 5e-25 87.8 0.0 1.1e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG81623.1 - 5.8e-19 68.5 0.0 1.3e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG81623.1 - 4.7e-16 58.6 0.3 4.7e-16 58.6 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81623.1 - 4.1e-07 30.2 0.0 2.3e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG81623.1 - 7.1e-07 28.9 0.8 1.8e-06 27.7 0.8 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Prefoldin_3 PF13758.6 GBG81623.1 - 0.035 14.1 0.1 2.6 8.2 0.0 3.1 1 1 1 2 2 2 0 Prefoldin subunit DUF1471 PF07338.13 GBG81623.1 - 0.074 13.0 0.4 8 6.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) zf-H2C2 PF09337.10 GBG81623.1 - 0.11 12.7 0.0 0.41 10.9 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger DUF1664 PF07889.12 GBG81623.1 - 0.94 9.5 2.5 5.2 7.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4719 PF15843.5 GBG81623.1 - 1.2 9.2 10.3 2.4 8.2 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) RT_RNaseH_2 PF17919.1 GBG81624.1 - 1.6e-26 92.3 0.0 3.4e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81624.1 - 1.3e-23 83.3 0.0 2.5e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81624.1 - 2e-18 66.7 0.0 3.2e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81624.1 - 1.2e-15 57.4 1.6 2.8e-15 56.2 1.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81624.1 - 2e-06 28.0 0.0 4.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81624.1 - 5.5e-05 23.6 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81624.1 - 0.00055 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81624.1 - 0.0018 18.9 0.0 0.0034 18.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG81624.1 - 0.071 13.3 0.2 0.21 11.9 0.2 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG81624.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease VanY PF02557.17 GBG81625.1 - 1.1e-20 73.8 0.0 1.2e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Spc24 PF08286.11 GBG81626.1 - 0.3 11.3 11.7 0.52 10.6 1.6 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 GBG81626.1 - 0.68 10.4 2.5 24 5.4 0.1 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DASH_Dam1 PF08653.10 GBG81626.1 - 2.3 8.1 4.0 11 5.9 0.2 3.3 3 1 1 4 4 4 0 DASH complex subunit Dam1 HIP1_clath_bdg PF16515.5 GBG81626.1 - 2.4 8.8 26.0 0.045 14.4 6.6 3.6 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 GBG81626.1 - 2.5 7.4 18.6 1.3 8.3 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 GBG81626.1 - 4.9 7.5 11.3 1.2 9.5 2.0 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myb_DNA-bind_4 PF13837.6 GBG81628.1 - 0.00015 22.1 3.0 0.00025 21.4 3.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF3357 PF11837.8 GBG81628.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) MHC_I PF00129.18 GBG81628.1 - 0.16 11.5 0.3 9.5 5.7 0.1 2.2 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 DDE_Tnp_4 PF13359.6 GBG81629.1 - 7.2e-12 45.2 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81629.1 - 1e-07 31.8 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81629.1 - 0.06 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain XRN_M PF17846.1 GBG81631.1 - 0.18 10.7 1.1 0.25 10.3 1.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain CDC45 PF02724.14 GBG81631.1 - 0.25 9.6 22.0 0.0042 15.5 9.8 2.1 2 0 0 2 2 2 0 CDC45-like protein V_ATPase_I PF01496.19 GBG81631.1 - 1.6 6.5 2.4 2.2 6.1 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 GBG81632.1 - 1.8e-24 86.6 0.0 3.4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG81632.1 - 3.1e-08 33.2 0.0 5.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 GBG81632.1 - 0.2 11.2 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Glycolytic PF00274.19 GBG81633.1 - 1.2e-170 566.9 0.0 1.3e-170 566.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I RT_RNaseH_2 PF17919.1 GBG81634.1 - 2.2e-22 79.0 0.0 1.8e-20 72.8 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81634.1 - 2.8e-22 79.0 0.0 1.3e-21 76.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81634.1 - 2.7e-07 30.8 0.1 2.2e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG81634.1 - 0.00039 20.5 0.0 0.0014 18.7 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Gln-synt_C PF00120.24 GBG81635.1 - 3.1e-15 56.0 0.0 2.6e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG81635.1 - 4.6e-11 42.3 0.0 8.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Glycolytic PF00274.19 GBG81636.1 - 4e-116 387.6 0.0 4.7e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glycolytic PF00274.19 GBG81637.1 - 5.3e-170 564.7 0.0 6e-170 564.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Sua5_yciO_yrdC PF01300.18 GBG81638.1 - 3e-40 137.6 0.0 4.2e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Glycolytic PF00274.19 GBG81639.1 - 4.3e-169 561.8 0.0 6.9e-169 561.1 0.0 1.3 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glycolytic PF00274.19 GBG81642.1 - 1.8e-23 82.8 0.0 3e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Exo_endo_phos PF03372.23 GBG81643.1 - 9.2e-06 25.3 0.2 2.9e-05 23.7 0.2 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG81643.1 - 0.12 12.2 0.4 5 7.0 0.0 3.2 3 1 0 3 3 3 0 Endonuclease-reverse transcriptase NgoMIV_restric PF09015.10 GBG81643.1 - 0.29 10.2 0.4 1.2 8.2 0.1 1.9 2 0 0 2 2 2 0 NgoMIV restriction enzyme RXT2_N PF08595.11 GBG81645.1 - 0.36 10.8 2.5 0.72 9.9 2.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Trypan_PARP PF05887.11 GBG81645.1 - 1.1 9.2 11.8 0.13 12.3 6.8 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RT_RNaseH_2 PF17919.1 GBG81646.1 - 1.3e-15 57.2 0.0 2.5e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81646.1 - 2.2e-14 53.5 0.2 3.8e-14 52.7 0.2 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81646.1 - 0.00048 20.4 0.0 0.00095 19.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG81647.1 - 4.3e-08 33.4 0.4 7.4e-08 32.7 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG81647.1 - 0.14 12.4 0.9 0.28 11.4 0.9 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain Gln-synt_C PF00120.24 GBG81648.1 - 3.7e-15 55.8 0.0 2.4e-12 46.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG81648.1 - 4.6e-11 42.3 0.0 8.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 GBG81649.1 - 1.2e-14 54.1 0.0 8.7e-12 44.7 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG81649.1 - 4.7e-11 42.3 0.0 8.2e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DDE_Tnp_4 PF13359.6 GBG81650.1 - 2.4e-29 102.1 0.0 6e-29 100.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81650.1 - 5.3e-10 39.2 0.0 8.5e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81650.1 - 0.04 13.5 0.6 5.9 6.5 0.0 2.7 3 0 0 3 3 3 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG81652.1 - 0.0076 16.6 0.5 0.086 13.2 0.2 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG81653.1 - 2.9e-25 88.2 0.0 5.1e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81653.1 - 2.8e-23 82.2 0.0 1.9e-22 79.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81653.1 - 2.7e-10 40.1 0.0 4.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YL1 PF05764.13 GBG81653.1 - 0.044 13.9 12.2 0.067 13.3 12.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GBG81653.1 - 0.7 8.0 10.7 0.94 7.6 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG81653.1 - 3.1 6.0 10.8 4.8 5.4 10.8 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.8 GBG81653.1 - 4 7.2 12.3 6.7 6.5 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Gln-synt_C PF00120.24 GBG81654.1 - 4e-15 55.6 0.0 2.2e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG81654.1 - 8.3e-11 41.5 0.0 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain BSP_II PF05432.11 GBG81657.1 - 1 9.0 43.5 0.052 13.2 35.4 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Gln-synt_C PF00120.24 GBG81658.1 - 6.7e-15 54.9 0.0 4.3e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG81658.1 - 4.6e-11 42.3 0.0 8.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 GBG81661.1 - 7.2e-15 54.8 0.0 5.3e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG81661.1 - 3.5e-11 42.7 0.0 6.6e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Glycolytic PF00274.19 GBG81662.1 - 2.5e-170 565.8 0.0 2.8e-170 565.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DAHP_synth_2 PF01474.16 GBG81664.1 - 3.2e-197 655.3 0.0 5.4e-197 654.6 0.0 1.4 1 0 0 1 1 1 1 Class-II DAHP synthetase family RVT_1 PF00078.27 GBG81664.1 - 8.1e-36 123.6 0.0 1.5e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81664.1 - 1.8e-24 85.6 0.0 1.2e-23 83.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81664.1 - 6e-22 77.9 0.0 2.3e-21 76.1 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mic1 PF07035.12 GBG81664.1 - 1.8e-19 70.0 0.0 4.9e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Retrotrans_gag PF03732.17 GBG81664.1 - 0.046 14.0 0.1 0.21 11.9 0.1 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein DUF2730 PF10805.8 GBG81665.1 - 0.032 14.3 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) RVT_1 PF00078.27 GBG81666.1 - 1.3e-08 34.6 0.2 3.4e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG81666.1 - 4.7e-07 29.7 0.0 7.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81666.1 - 1.1e-06 29.2 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81666.1 - 9.9e-06 26.0 0.0 2.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG81666.1 - 6.4e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF452 PF04301.13 GBG81666.1 - 0.024 14.1 0.1 13 5.2 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF452) DUF659 PF04937.15 GBG81669.1 - 7.3e-32 110.3 0.1 1e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) MA-Mit PF09245.10 GBG81669.1 - 0.26 10.8 0.1 0.41 10.1 0.1 1.2 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen gag-asp_proteas PF13975.6 GBG81670.1 - 3.1e-07 30.9 0.1 7.2e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81670.1 - 7.3e-06 26.6 0.1 1.8e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG81670.1 - 0.00026 20.8 0.1 0.00042 20.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG81670.1 - 0.0059 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG81670.1 - 0.043 13.9 1.9 0.078 13.1 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG81671.1 - 0.064 12.9 2.0 0.068 12.9 0.3 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG81671.1 - 0.42 10.8 2.7 0.85 9.8 2.7 1.5 1 0 0 1 1 1 0 Zinc knuckle FYVE PF01363.21 GBG81673.1 - 0.033 14.3 1.2 0.058 13.5 1.2 1.3 1 0 0 1 1 1 0 FYVE zinc finger gag-asp_proteas PF13975.6 GBG81675.1 - 2.3e-07 31.3 0.4 6.6e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81675.1 - 0.0001 22.9 0.3 0.00054 20.5 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG81675.1 - 0.0053 17.0 0.1 0.059 13.7 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein RVP PF00077.20 GBG81675.1 - 0.0066 16.7 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81675.1 - 0.099 12.4 1.1 0.19 11.5 1.1 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF3682 PF12446.8 GBG81675.1 - 2.8 8.4 14.3 11 6.5 14.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Retrotrans_gag PF03732.17 GBG81676.1 - 0.1 12.9 0.1 0.1 12.9 0.1 2.3 2 1 1 3 3 3 0 Retrotransposon gag protein Sporozoite_P67 PF05642.11 GBG81676.1 - 7.5 4.5 6.5 0.48 8.5 0.6 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF659 PF04937.15 GBG81677.1 - 2.7e-22 79.3 0.0 4.7e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG81677.1 - 0.087 13.0 0.2 6.4 7.0 0.0 3.0 3 0 0 3 3 3 0 Integrase core domain Retrotrans_gag PF03732.17 GBG81679.1 - 0.0037 17.5 0.1 0.29 11.4 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein NOP19 PF10863.8 GBG81679.1 - 0.097 12.5 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Nucleolar protein 19 DUF659 PF04937.15 GBG81680.1 - 5.8e-05 23.0 0.0 8.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG81681.1 - 9e-08 32.3 0.0 3.7e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81681.1 - 3e-06 27.2 0.1 6.9e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG81681.1 - 0.13 11.6 4.4 0.28 10.6 4.4 1.4 1 0 0 1 1 1 0 SDA1 DUF104 PF01954.16 GBG81682.1 - 0.094 13.2 0.2 1.8 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF104 Gln-synt_C PF00120.24 GBG81683.1 - 1.4e-16 60.5 0.0 1.7e-15 56.9 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG81683.1 - 7e-10 38.5 0.0 1.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Integrase_H2C2 PF17921.1 GBG81684.1 - 7.7e-16 58.0 1.0 1.5e-15 57.1 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81684.1 - 5e-06 26.7 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81684.1 - 0.00025 21.6 0.0 0.0006 20.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81684.1 - 0.0006 20.4 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG81684.1 - 0.0014 18.8 0.0 0.0037 17.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG81684.1 - 0.0071 16.6 0.1 0.021 15.1 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG81684.1 - 0.26 11.1 0.7 0.51 10.1 0.7 1.4 1 0 0 1 1 1 0 Aspartyl protease CLIP1_ZNF PF16641.5 GBG81685.1 - 0.044 13.7 1.4 0.093 12.6 1.4 1.6 1 0 0 1 1 1 0 CLIP1 zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG81686.1 - 0.016 14.8 0.3 0.038 13.7 0.3 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Filament PF00038.21 GBG81688.1 - 0.0016 18.1 5.8 0.0034 17.0 5.8 1.5 1 0 0 1 1 1 1 Intermediate filament protein Tup_N PF08581.10 GBG81688.1 - 0.0039 17.4 2.3 0.015 15.5 2.3 2.0 1 0 0 1 1 1 1 Tup N-terminal ATG16 PF08614.11 GBG81688.1 - 0.0077 16.5 5.0 0.0077 16.5 5.0 2.2 3 0 0 3 3 2 1 Autophagy protein 16 (ATG16) HALZ PF02183.18 GBG81688.1 - 0.013 15.7 0.5 0.051 13.8 0.5 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 GBG81688.1 - 0.023 15.1 3.7 0.023 15.1 3.7 2.8 3 1 0 3 3 3 0 Cell division protein ZapB DUF5082 PF16888.5 GBG81688.1 - 0.028 14.7 0.8 0.053 13.8 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) HAUS-augmin3 PF14932.6 GBG81688.1 - 0.034 13.7 3.2 0.62 9.6 3.8 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 AAA_23 PF13476.6 GBG81688.1 - 0.041 14.4 1.6 0.061 13.8 1.6 1.3 1 1 0 1 1 1 0 AAA domain OmpH PF03938.14 GBG81688.1 - 0.041 14.2 0.7 0.041 14.2 0.7 2.0 3 0 0 3 3 2 0 Outer membrane protein (OmpH-like) Prominin PF05478.11 GBG81688.1 - 0.045 11.7 0.7 0.065 11.2 0.7 1.2 1 0 0 1 1 1 0 Prominin GAS PF13851.6 GBG81688.1 - 0.1 11.9 7.5 0.026 13.9 3.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Med4 PF10018.9 GBG81688.1 - 0.11 12.2 4.8 0.056 13.1 2.1 1.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Nup54 PF13874.6 GBG81688.1 - 0.12 12.5 3.9 1.4 9.0 3.7 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF4407 PF14362.6 GBG81688.1 - 0.12 11.7 0.7 0.19 11.0 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CRA PF06589.11 GBG81688.1 - 0.12 12.5 4.5 0.23 11.6 4.5 1.7 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) kleA_kleC PF17383.2 GBG81688.1 - 0.13 12.6 5.6 0.11 12.8 1.4 2.8 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A UPF0449 PF15136.6 GBG81688.1 - 0.15 12.6 2.7 2.5 8.6 0.7 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Uds1 PF15456.6 GBG81688.1 - 0.15 12.2 8.1 0.62 10.2 2.9 2.4 2 0 0 2 2 2 0 Up-regulated During Septation Atg14 PF10186.9 GBG81688.1 - 0.18 10.9 1.1 0.33 10.0 1.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin_2 PF01920.20 GBG81688.1 - 0.32 11.0 10.7 0.83 9.6 2.9 3.2 2 1 1 3 3 3 0 Prefoldin subunit Gp-FAR-1 PF05823.12 GBG81688.1 - 0.34 11.3 2.6 0.69 10.3 0.6 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) bZIP_1 PF00170.21 GBG81688.1 - 1.6 8.9 13.0 0.061 13.4 5.3 2.7 2 0 0 2 2 1 0 bZIP transcription factor XkdW PF09636.10 GBG81688.1 - 1.6 8.8 5.2 0.72 10.0 0.4 2.5 2 2 1 3 3 3 0 XkdW protein UPF0242 PF06785.11 GBG81688.1 - 1.8 8.6 7.5 0.77 9.8 3.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MRPL52 PF18699.1 GBG81688.1 - 3.1 8.1 7.6 1.1 9.5 2.3 2.7 2 0 0 2 2 2 0 Mitoribosomal protein mL52 COG2 PF06148.11 GBG81688.1 - 4 7.5 9.5 0.11 12.6 2.2 2.2 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RVT_1 PF00078.27 GBG81690.1 - 2.9e-29 102.2 0.1 4.9e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81690.1 - 1.7e-12 47.3 0.0 6.8e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81690.1 - 1.7e-09 37.9 0.1 4.9e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81690.1 - 0.0029 17.8 0.0 0.015 15.5 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG81691.1 - 4.3e-06 27.0 1.3 9.3e-05 22.7 0.3 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG81691.1 - 0.21 11.9 0.9 2.1 8.7 0.1 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVP_2 PF08284.11 GBG81692.1 - 6.5e-05 22.7 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81692.1 - 0.0024 18.5 0.0 0.0058 17.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG81692.1 - 0.029 14.2 0.0 0.078 12.7 0.0 1.7 1 1 0 1 1 1 0 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG81692.1 - 0.064 13.8 0.0 0.25 11.9 0.0 2.0 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG81693.1 - 1.5e-27 95.5 0.0 3.1e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81693.1 - 4.6e-25 87.9 0.0 9e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81693.1 - 2.2e-14 53.3 0.1 4.8e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG81693.1 - 0.0072 16.2 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HNH_3 PF13392.6 GBG81693.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease PilN_bio_d PF18222.1 GBG81693.1 - 0.19 12.1 0.0 0.48 10.8 0.0 1.6 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain Asp_protease_2 PF13650.6 GBG81694.1 - 1.7e-07 31.8 0.0 6.4e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81694.1 - 5.2e-07 30.1 0.0 2.5e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81694.1 - 1.1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81694.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG81694.1 - 0.0022 18.2 0.0 0.0022 18.2 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein Plasmodium_Vir PF05795.11 GBG81694.1 - 8.7 5.7 9.6 27 4.0 9.6 1.9 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Asp_protease_2 PF13650.6 GBG81695.1 - 1.1e-07 32.4 0.0 4.8e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81695.1 - 3.6e-07 30.7 0.0 1.9e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81695.1 - 7.8e-06 25.7 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG81695.1 - 0.00015 21.9 1.8 0.0017 18.6 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG81695.1 - 0.00061 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease HIP1_clath_bdg PF16515.5 GBG81695.1 - 0.023 15.3 2.7 0.023 15.3 2.7 3.0 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 GBG81695.1 - 8 5.7 17.0 4.2 6.6 8.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF659 PF04937.15 GBG81696.1 - 1.6e-14 54.0 0.0 3.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81696.1 - 1.1e-08 34.7 0.2 2.4e-08 33.6 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Radial_spoke PF04712.12 GBG81697.1 - 0.037 13.0 6.9 0.039 12.9 6.9 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Clathrin_lg_ch PF01086.17 GBG81697.1 - 0.046 13.8 17.7 0.6 10.1 0.1 2.1 2 0 0 2 2 2 0 Clathrin light chain Nop14 PF04147.12 GBG81697.1 - 0.092 10.9 9.9 0.11 10.7 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family Afaf PF15339.6 GBG81697.1 - 0.46 10.2 3.2 0.67 9.6 3.2 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor PAC1 PF16094.5 GBG81697.1 - 1.6 7.9 5.9 2.2 7.4 5.9 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 PBP1_TM PF14812.6 GBG81697.1 - 2.8 8.4 11.0 0.64 10.4 6.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 GBG81697.1 - 4.3 5.5 7.9 4.6 5.4 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 GBG81697.1 - 5.5 6.6 10.9 6.7 6.3 10.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DNA_pol_phi PF04931.13 GBG81697.1 - 6.5 4.7 11.4 7 4.6 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi BSP_II PF05432.11 GBG81697.1 - 7.8 6.1 20.8 11 5.6 20.8 1.3 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) PET117 PF15786.5 GBG81697.1 - 9.8 6.5 7.8 20 5.5 7.8 1.5 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Brix PF04427.18 GBG81698.1 - 1.3e-31 110.2 0.0 2.7e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Brix domain DUF659 PF04937.15 GBG81698.1 - 1.9e-27 96.0 0.0 3.8e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) HTH_Tnp_Tc5 PF03221.16 GBG81698.1 - 1.5e-13 50.6 0.7 1.2e-12 47.6 0.1 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Dimer_Tnp_hAT PF05699.14 GBG81698.1 - 1.4e-10 40.8 0.2 3.3e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_1 PF03184.19 GBG81698.1 - 5.9e-09 35.8 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG81699.1 - 5.7e-28 97.9 0.0 1.7e-27 96.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81699.1 - 2.6e-10 40.5 0.2 7e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81699.1 - 4.3e-10 39.8 0.0 1.6e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG81699.1 - 2.6e-05 24.8 0.0 5.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81699.1 - 6.5e-05 23.4 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81699.1 - 9.7e-05 22.2 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG81699.1 - 0.00026 21.0 0.0 0.00072 19.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81699.1 - 0.00036 20.6 0.4 0.0009 19.3 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG81699.1 - 0.0041 16.9 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG81699.1 - 0.13 12.6 0.0 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein Dynamitin PF04912.14 GBG81700.1 - 0.0037 16.7 3.8 0.0037 16.7 3.8 1.5 2 0 0 2 2 2 1 Dynamitin Lbh PF15317.6 GBG81700.1 - 0.18 12.7 5.7 0.37 11.7 1.9 2.5 1 1 1 2 2 2 0 Cardiac transcription factor regulator, Developmental protein DUF641 PF04859.12 GBG81700.1 - 2.1 8.7 6.8 0.53 10.6 0.1 2.8 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) YabA PF06156.13 GBG81700.1 - 2.2 8.9 9.0 0.096 13.3 2.2 2.2 3 1 0 3 3 3 0 Initiation control protein YabA SAB PF04382.13 GBG81700.1 - 3.9 7.6 8.8 9.4 6.4 0.0 3.5 3 1 0 3 3 3 0 SAB domain DUF16 PF01519.16 GBG81700.1 - 4.1 8.0 11.7 0.49 10.9 1.5 2.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 RT_RNaseH_2 PF17919.1 GBG81701.1 - 5.3e-21 74.5 0.0 1.5e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81701.1 - 1.4e-18 67.1 0.0 3.3e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81701.1 - 1.4e-09 37.8 0.0 2.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4683 PF15735.5 GBG81701.1 - 3.5 7.2 14.5 5.8 6.4 14.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) RVT_1 PF00078.27 GBG81702.1 - 2.7e-64 216.7 0.7 8.6e-33 113.7 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81702.1 - 7.8e-45 151.0 0.0 2e-26 91.9 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81702.1 - 9.3e-33 112.7 0.0 4.3e-25 88.0 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Nexin_C PF08628.12 GBG81702.1 - 5.8e-25 88.1 0.2 3.4e-24 85.6 0.0 2.6 2 0 0 2 2 1 1 Sorting nexin C terminal Asp_protease_2 PF13650.6 GBG81702.1 - 3.9e-14 53.1 0.0 2.2e-06 28.2 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG81702.1 - 5.2e-11 42.5 0.0 0.00022 21.0 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG81702.1 - 8e-10 39.2 0.0 4e-05 24.1 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG81702.1 - 4.8e-06 26.8 1.7 0.35 11.2 0.0 4.7 3 0 0 3 3 3 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG81702.1 - 4.4e-05 23.3 0.0 0.006 16.4 0.0 3.1 3 0 0 3 3 3 1 Aspartyl protease RNR_Alpha PF17975.1 GBG81702.1 - 0.043 14.3 0.3 6.4 7.3 0.3 3.0 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain DUF1758 PF05585.12 GBG81702.1 - 0.18 11.6 0.0 0.77 9.5 0.0 1.9 2 0 0 2 2 2 0 Putative peptidase (DUF1758) CLZ PF16526.5 GBG81702.1 - 7.6 7.0 13.1 2.8 8.3 0.9 4.5 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LELP1 PF15042.6 GBG81702.1 - 9.4 6.7 8.9 0.23 11.9 0.1 2.9 2 0 0 2 2 1 0 Late cornified envelope-like proline-rich protein 1 RT_RNaseH_2 PF17919.1 GBG81703.1 - 9e-29 99.5 0.0 2.6e-28 98.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81703.1 - 2.4e-27 95.3 0.0 5.1e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81703.1 - 5.7e-17 62.0 0.2 4.7e-14 52.4 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4790 PF16037.5 GBG81703.1 - 0.28 11.7 2.3 0.9 10.0 2.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4790) PXA PF02194.15 GBG81704.1 - 4.8e-31 108.2 0.0 7.3e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 PXA domain PX PF00787.24 GBG81704.1 - 0.00041 20.3 0.0 0.00083 19.3 0.0 1.4 1 0 0 1 1 1 1 PX domain PXA PF02194.15 GBG81705.1 - 1.6e-14 54.3 0.4 4e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 PXA domain PX PF00787.24 GBG81705.1 - 0.00031 20.7 0.0 0.00073 19.5 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF3138 PF11336.8 GBG81705.1 - 2 6.9 4.0 3.1 6.3 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PXA PF02194.15 GBG81706.1 - 1.2e-11 44.9 0.0 2.5e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 PXA domain HAUS-augmin3 PF14932.6 GBG81707.1 - 5.9e-32 111.3 0.0 5.9e-32 111.3 0.0 4.0 3 1 1 4 4 4 2 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 GBG81707.1 - 8 6.5 9.7 17 5.5 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 GBG81708.1 - 0.009 16.3 0.1 0.023 15.0 0.1 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG81709.1 - 6.7e-41 138.2 4.2 5.2e-20 71.3 0.2 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG81709.1 - 1.1e-40 138.1 3.6 4.6e-21 75.1 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81709.1 - 1.1e-34 118.5 0.1 4.6e-22 77.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81709.1 - 6.7e-26 90.8 0.1 5.9e-15 55.5 0.0 3.2 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG81709.1 - 3.1e-19 69.4 0.1 1.6e-18 67.1 0.1 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG81709.1 - 9.7e-11 41.7 0.1 0.00079 19.6 0.0 3.6 4 0 0 4 4 4 2 H2C2 zinc finger RVP_2 PF08284.11 GBG81709.1 - 1.2e-09 38.0 0.0 2.9e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81709.1 - 1.6e-07 31.8 0.0 3.6e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81709.1 - 6.2e-06 26.7 0.0 1.6e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG81709.1 - 0.0035 17.1 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease FAM76 PF16046.5 GBG81709.1 - 0.3 10.4 8.4 0.69 9.2 8.4 1.5 1 0 0 1 1 1 0 FAM76 protein RVT_1 PF00078.27 GBG81710.1 - 2.8e-26 92.4 0.2 5e-26 91.6 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81710.1 - 1.5e-05 25.2 0.0 3.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain CENP-H PF05837.12 GBG81710.1 - 0.072 13.5 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) YabA PF06156.13 GBG81710.1 - 0.32 11.7 1.1 0.49 11.1 0.0 1.9 2 0 0 2 2 2 0 Initiation control protein YabA GAS PF13851.6 GBG81710.1 - 2 7.7 6.0 2.7 7.3 1.1 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding RVT_1 PF00078.27 GBG81711.1 - 4.9e-26 91.6 0.0 7.7e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Macro PF01661.21 GBG81711.1 - 6.3e-06 26.2 0.0 1.9e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Macro domain DUF1223 PF06764.11 GBG81711.1 - 0.11 12.5 3.9 0.27 11.2 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) PA26 PF04636.13 GBG81711.1 - 2.3 7.0 9.0 4.3 6.1 9.0 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) VPS38 PF17649.1 GBG81711.1 - 8 5.2 9.5 12 4.7 9.5 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 RT_RNaseH_2 PF17919.1 GBG81712.1 - 2.8e-25 88.2 0.0 5.6e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81712.1 - 1.1e-20 73.9 0.0 2.5e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81712.1 - 3.7e-15 56.2 0.0 8.9e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG81712.1 - 1e-10 41.5 0.0 3.3e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC_2 PF13696.6 GBG81712.1 - 0.0051 16.6 0.7 0.012 15.4 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG81712.1 - 0.014 16.0 0.0 0.044 14.4 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG81712.1 - 0.034 14.4 0.8 0.67 10.3 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG81712.1 - 0.044 13.3 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 GBG81712.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease rve_3 PF13683.6 GBG81712.1 - 0.15 11.9 0.0 0.52 10.1 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain zf-CCHC PF00098.23 GBG81712.1 - 0.26 11.4 12.7 2.9 8.1 0.9 3.0 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG81713.1 - 5.9e-64 215.6 0.9 2.4e-34 118.8 0.1 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81713.1 - 9.3e-29 99.4 0.0 2.8e-28 97.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81713.1 - 1e-27 96.5 0.0 2.5e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG81713.1 - 7.6e-16 58.5 0.0 1.2e-06 29.1 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG81713.1 - 7.5e-14 52.1 0.0 2.6e-06 27.9 0.0 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81713.1 - 3.7e-13 49.4 0.0 3.7e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81713.1 - 2.2e-08 34.0 0.0 0.00055 19.7 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease DUF1758 PF05585.12 GBG81713.1 - 0.013 15.3 0.0 0.06 13.1 0.0 1.9 2 0 0 2 2 2 0 Putative peptidase (DUF1758) RVP PF00077.20 GBG81713.1 - 0.022 15.0 0.0 4.8 7.5 0.0 2.9 3 0 0 3 3 3 0 Retroviral aspartyl protease Rhamno_transf PF11316.8 GBG81713.1 - 0.09 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase RVT_1 PF00078.27 GBG81714.1 - 6.1e-20 71.7 0.1 1e-19 71.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG81714.1 - 0.00012 22.7 0.0 0.00035 21.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81714.1 - 0.00087 19.8 0.0 0.0023 18.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG81714.1 - 0.0032 17.3 0.0 0.0097 15.7 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG81714.1 - 0.0092 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Adaptin_binding PF10199.9 GBG81714.1 - 0.44 11.2 7.0 0.37 11.4 3.3 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RT_RNaseH_2 PF17919.1 GBG81715.1 - 2.3e-21 75.7 0.0 4.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81715.1 - 2.8e-21 75.8 0.0 4.6e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81715.1 - 2.9e-18 65.7 0.4 6.2e-18 64.6 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG81715.1 - 1.5e-09 37.7 1.5 6.6e-09 35.6 0.1 2.4 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG81715.1 - 0.016 15.4 0.1 0.035 14.3 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Integrin_b_cyt PF08725.11 GBG81715.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RT_RNaseH_2 PF17919.1 GBG81721.1 - 6.6e-32 109.5 0.1 2.9e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81721.1 - 3.6e-29 101.1 0.2 3.2e-28 98.1 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81721.1 - 7.4e-14 52.0 0.1 3.2e-13 49.9 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG81721.1 - 4.1e-09 36.4 0.7 8.7e-09 35.4 0.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG81721.1 - 0.15 12.4 0.5 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein DUF4619 PF15398.6 GBG81722.1 - 4.5 6.7 16.6 4.6 6.7 15.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4619) Asp_protease_2 PF13650.6 GBG81723.1 - 1.4e-07 32.0 0.0 3.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81723.1 - 7.3e-07 29.7 0.0 1.7e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG81723.1 - 3.4e-06 26.7 0.0 5.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG81723.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81723.1 - 0.00078 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG81723.1 - 0.062 13.5 0.2 0.21 11.8 0.1 1.9 2 0 0 2 2 2 0 Integrase core domain zf-CCHC PF00098.23 GBG81724.1 - 0.18 11.9 4.2 0.37 11.0 4.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Histone PF00125.24 GBG81727.1 - 9.4e-22 77.8 0.0 2e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FlaC_arch PF05377.11 GBG81729.1 - 0.0062 16.9 4.1 0.0062 16.9 4.1 4.0 4 0 0 4 4 4 2 Flagella accessory protein C (FlaC) DUF3969 PF13108.6 GBG81729.1 - 0.17 11.9 1.8 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) Macoilin PF09726.9 GBG81729.1 - 1.1 7.8 25.5 1.7 7.1 13.4 2.2 2 0 0 2 2 2 0 Macoilin family Laminin_II PF06009.12 GBG81729.1 - 1.1 9.3 13.8 1.1 9.3 10.7 2.3 1 1 0 1 1 1 0 Laminin Domain II Hemagglutinin PF00509.18 GBG81729.1 - 1.4 7.3 5.8 3.9 5.8 5.2 1.8 1 1 0 1 1 1 0 Haemagglutinin Prominin PF05478.11 GBG81729.1 - 2.7 5.9 5.5 4 5.3 5.5 1.2 1 0 0 1 1 1 0 Prominin ATG16 PF08614.11 GBG81729.1 - 3.6 7.8 30.1 0.048 13.9 19.8 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 GBG81729.1 - 4.1 7.7 10.8 0.94 9.7 0.9 3.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GBG81729.1 - 4.1 7.6 25.5 0.77 9.9 8.3 3.4 2 1 1 3 3 3 0 bZIP transcription factor DUF2730 PF10805.8 GBG81729.1 - 6.5 6.9 13.2 1.1 9.4 1.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DDE_Tnp_4 PF13359.6 GBG81730.1 - 7.9e-33 113.4 0.0 2.3e-32 111.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81730.1 - 7.1e-14 51.9 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81730.1 - 0.00037 20.2 0.4 0.86 9.2 0.0 3.1 3 0 0 3 3 3 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG81731.1 - 7.2e-06 26.3 0.9 7.7e-05 23.0 0.3 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG81731.1 - 0.041 13.9 2.2 0.12 12.4 2.2 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2815 PF10991.8 GBG81732.1 - 0.018 15.0 0.0 6.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2815) MAPEG PF01124.18 GBG81732.1 - 0.025 14.5 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 MAPEG family RCDG1 PF15725.5 GBG81732.1 - 0.029 14.8 1.9 0.029 14.8 1.9 2.2 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Trypsin PF00089.26 GBG81733.1 - 2.2e-34 119.2 0.3 1.7e-32 113.0 0.3 2.2 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GBG81733.1 - 0.045 14.7 0.0 0.15 13.0 0.0 1.9 2 0 0 2 2 2 0 Trypsin-like peptidase domain Ribosomal_S17 PF00366.20 GBG81734.1 - 7.1e-25 86.9 2.3 9.9e-25 86.4 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 FliMN_C PF01052.20 GBG81734.1 - 0.13 12.3 0.1 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term Fib_alpha PF08702.10 GBG81735.1 - 0.64 10.2 19.5 0.13 12.4 10.7 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family BST2 PF16716.5 GBG81737.1 - 0.0021 18.6 5.2 0.0021 18.6 5.2 10.6 4 2 5 11 11 11 3 Bone marrow stromal antigen 2 TPR_MLP1_2 PF07926.12 GBG81738.1 - 2.7e-23 82.4 24.6 2.7e-23 82.4 24.6 8.1 3 1 6 9 9 9 2 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 GBG81738.1 - 0.017 15.1 0.6 0.017 15.1 0.6 4.4 5 1 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus COMM_domain PF07258.14 GBG81738.1 - 0.2 11.8 8.4 0.26 11.4 1.0 3.5 3 0 0 3 3 3 0 COMM domain FlaC_arch PF05377.11 GBG81738.1 - 0.2 12.1 41.6 1.5 9.3 2.6 8.0 4 4 3 7 7 7 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 GBG81739.1 - 2.7e-23 82.4 24.6 2.7e-23 82.4 24.6 8.1 3 1 6 9 9 9 2 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 GBG81739.1 - 0.017 15.1 0.6 0.017 15.1 0.6 4.4 5 1 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus COMM_domain PF07258.14 GBG81739.1 - 0.2 11.8 8.4 0.26 11.4 1.0 3.5 3 0 0 3 3 3 0 COMM domain FlaC_arch PF05377.11 GBG81739.1 - 0.2 12.1 41.6 1.5 9.3 2.6 8.0 4 4 3 7 7 7 0 Flagella accessory protein C (FlaC) XRCC4 PF06632.12 GBG81740.1 - 1.3e-18 66.9 1.6 1.3e-18 66.9 1.6 1.9 2 0 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PKcGMP_CC PF16808.5 GBG81740.1 - 0.01 15.7 2.2 0.03 14.2 2.2 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase VPS38 PF17649.1 GBG81740.1 - 0.023 13.6 0.2 0.038 12.9 0.2 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Neur_chan_memb PF02932.16 GBG81740.1 - 0.84 9.6 6.8 0.4 10.7 1.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Vps55 PF04133.14 GBG81741.1 - 7.6e-31 106.5 6.1 1.2e-30 105.8 6.1 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting 55 CHCH PF06747.13 GBG81741.1 - 4.1e-08 33.2 3.4 7.1e-08 32.4 3.4 1.4 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 GBG81741.1 - 2.9e-06 27.4 3.1 4.7e-06 26.7 3.1 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CX9C PF16860.5 GBG81741.1 - 0.0055 16.7 2.4 0.011 15.7 2.4 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Myc_N PF01056.18 GBG81741.1 - 0.0087 16.0 1.4 0.011 15.6 1.4 1.1 1 0 0 1 1 1 1 Myc amino-terminal region FAM176 PF14851.6 GBG81741.1 - 0.01 15.5 2.3 0.019 14.6 2.3 1.4 1 0 0 1 1 1 0 FAM176 family DUF2052 PF09747.9 GBG81741.1 - 0.032 14.4 5.3 0.043 13.9 5.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ribosomal_60s PF00428.19 GBG81741.1 - 0.035 14.7 2.0 0.035 14.7 2.0 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pox_Ag35 PF03286.14 GBG81741.1 - 0.14 12.0 1.8 0.18 11.6 1.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4611 PF15387.6 GBG81741.1 - 0.45 10.8 6.1 0.73 10.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) WRNPLPNID PF15017.6 GBG81741.1 - 0.74 10.7 7.5 1.3 10.0 7.5 1.3 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box M_domain PF12938.7 GBG81741.1 - 2.2 8.0 7.0 0.091 12.5 0.9 1.6 2 0 0 2 2 2 0 M domain of GW182 Cmc1 PF08583.10 GBG81741.1 - 4.9 7.3 8.8 7 6.8 0.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 GBG81741.1 - 7.5 7.0 9.4 34 4.9 9.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) TMEM214 PF10151.9 GBG81742.1 - 2.9e-14 52.5 0.9 3.3e-08 32.5 0.1 2.2 2 0 0 2 2 2 2 TMEM214, C-terminal, caspase 4 activator Dendrin PF15498.6 GBG81742.1 - 1.7 7.3 7.2 4.5 5.9 1.1 2.1 2 0 0 2 2 2 0 Nephrin and CD2AP-binding protein, Dendrin ETC_C1_NDUFA4 PF04800.12 GBG81743.1 - 5.6e-35 119.5 0.6 7.3e-35 119.1 0.6 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region Mito_fiss_Elm1 PF06258.11 GBG81744.1 - 8.3e-108 360.2 0.0 9.7e-108 360.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial fission ELM1 Epimerase_2 PF02350.19 GBG81744.1 - 0.019 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Acyl_transf_1 PF00698.21 GBG81745.1 - 2e-20 73.6 0.7 4.2e-20 72.5 0.7 1.5 1 1 0 1 1 1 1 Acyl transferase domain Glyco_transf_34 PF05637.12 GBG81747.1 - 1.8e-11 44.3 0.7 8.7e-11 42.0 0.7 1.8 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 GBG81747.1 - 0.018 15.0 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 GBG81747.1 - 0.034 13.7 0.8 0.081 12.5 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF273 RRM_1 PF00076.22 GBG81748.1 - 1.7e-75 248.8 7.7 5.6e-19 67.7 0.0 5.9 6 1 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sedlin_N PF04628.13 GBG81748.1 - 2.4e-29 102.1 0.1 4.6e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RRM_5 PF13893.6 GBG81748.1 - 1.4e-07 31.1 0.0 0.72 9.5 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 GBG81748.1 - 2.9e-05 24.1 1.9 0.049 13.7 0.0 3.9 4 0 0 4 4 4 2 Smg-4/UPF3 family PHM7_cyt PF14703.6 GBG81748.1 - 3.2e-05 24.3 0.4 0.78 10.0 0.0 4.4 4 1 1 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 GBG81748.1 - 3.5e-05 23.6 0.0 0.2 11.5 0.0 4.6 5 0 0 5 5 5 1 Occluded RNA-recognition motif Sybindin PF04099.12 GBG81748.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Sybindin-like family RRM_7 PF16367.5 GBG81748.1 - 0.0073 16.4 0.1 21 5.3 0.0 4.8 5 0 0 5 5 5 0 RNA recognition motif RRM_Rrp7 PF17799.1 GBG81748.1 - 0.065 13.0 0.1 16 5.2 0.0 3.7 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain Tubulin PF00091.25 GBG81749.1 - 1.3e-69 234.4 0.0 2.1e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG81749.1 - 1.8e-41 141.2 0.3 2.7e-41 140.7 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GBG81749.1 - 0.00038 20.7 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 GBG81749.1 - 0.00072 18.9 0.2 0.0018 17.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 GBG81749.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain zf-HC5HC2H_2 PF13832.6 GBG81750.1 - 6.8e-26 90.6 2.9 6.8e-26 90.6 2.9 5.0 5 0 0 5 5 5 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GBG81750.1 - 5e-19 68.3 2.2 5e-19 68.3 2.2 6.1 6 0 0 6 6 6 3 PHD-like zinc-binding domain PHD PF00628.29 GBG81750.1 - 2.5e-17 62.5 70.3 1e-07 31.7 5.9 5.9 5 0 0 5 5 5 5 PHD-finger DDT PF02791.17 GBG81750.1 - 4.1e-10 39.8 0.8 7.4e-10 39.0 0.8 1.4 1 0 0 1 1 1 1 DDT domain PHD_2 PF13831.6 GBG81750.1 - 2.9e-05 23.5 4.2 2.9e-05 23.5 4.2 5.7 6 0 0 6 6 6 2 PHD-finger WHIM1 PF15612.6 GBG81750.1 - 0.00013 21.4 0.5 0.00028 20.3 0.5 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 C1_1 PF00130.22 GBG81750.1 - 0.0018 18.1 7.0 0.0018 18.1 7.0 6.4 7 0 0 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Mtf2_C PF14061.6 GBG81750.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 AT_hook PF02178.19 GBG81750.1 - 0.17 11.9 14.6 4 7.6 3.8 3.7 2 0 0 2 2 2 0 AT hook motif CENP-B_dimeris PF09026.10 GBG81750.1 - 1.4 9.3 5.4 5.1 7.6 5.4 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.32 GBG81751.1 - 2.1e-26 91.6 10.4 1.6e-05 25.6 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG81751.1 - 3.4e-15 56.1 3.3 4.7e-05 23.6 0.1 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG81751.1 - 0.0013 18.6 0.0 2 8.3 0.0 3.3 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GBG81751.1 - 0.018 14.1 0.9 2.1 7.2 0.0 3.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 GBG81751.1 - 0.057 12.2 0.1 2 7.1 0.0 2.3 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region TOC159_MAD PF11886.8 GBG81752.1 - 2.6e-105 351.1 0.0 4.1e-105 350.5 0.0 1.3 1 0 0 1 1 1 1 Translocase of chloroplast 159/132, membrane anchor domain AIG1 PF04548.16 GBG81752.1 - 3.1e-25 88.8 0.0 6.1e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GBG81752.1 - 5.6e-08 32.9 0.0 1.9e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 GBG81752.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Septin Gtr1_RagA PF04670.12 GBG81752.1 - 0.04 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GBG81752.1 - 0.043 13.3 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 GBG81752.1 - 0.048 14.0 0.1 0.87 9.9 0.1 2.8 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 GBG81752.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Mlf1IP PF10248.9 GBG81754.1 - 1.7e-23 83.5 5.2 1.7e-23 83.5 5.2 2.2 1 1 1 2 2 2 2 Myelodysplasia-myeloid leukemia factor 1-interacting protein BatD PF13584.6 GBG81755.1 - 0.0082 15.0 0.1 0.0095 14.8 0.1 1.0 1 0 0 1 1 1 1 Oxygen tolerance RVT_1 PF00078.27 GBG81756.1 - 9.9e-28 97.2 0.7 3.2e-27 95.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG81756.1 - 1.1e-07 31.7 0.0 2.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81756.1 - 4.8e-07 30.3 0.0 1.7e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81756.1 - 2.7e-05 24.6 0.0 0.00012 22.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG81756.1 - 0.029 14.6 5.7 0.038 14.3 0.1 3.6 4 0 0 4 4 4 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG81756.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TSP9 PF11493.8 GBG81756.1 - 1.8 9.3 4.1 0.82 10.4 0.1 2.4 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 CENP-B_dimeris PF09026.10 GBG81757.1 - 0.00041 20.7 9.9 0.00066 20.0 9.9 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Orf78 PF06024.12 GBG81757.1 - 0.047 14.0 0.1 0.047 14.0 0.1 2.2 1 1 1 2 2 2 0 Orf78 (ac78) Phage_holin_3_6 PF07332.11 GBG81757.1 - 0.32 11.1 15.5 3.8 7.6 12.2 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III GCIP PF13324.6 GBG81757.1 - 0.69 9.5 8.1 0.91 9.1 8.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RXT2_N PF08595.11 GBG81757.1 - 0.79 9.7 7.5 1.1 9.3 7.5 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 GBG81757.1 - 1.2 7.1 15.5 1.6 6.7 15.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF1676 PF07898.13 GBG81757.1 - 8.1 6.4 19.5 15 5.5 19.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) DUF2207 PF09972.9 GBG81757.1 - 8.2 5.1 6.6 2.4 6.8 3.7 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RRN3 PF05327.11 GBG81757.1 - 9.7 4.6 9.2 2.7 6.4 6.2 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 GBG81757.1 - 10 6.0 11.7 12 5.7 11.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RT_RNaseH PF17917.1 GBG81759.1 - 1.3e-20 73.6 0.2 3.3e-20 72.3 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81759.1 - 7.7e-18 64.4 0.1 1.6e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG81759.1 - 2.2e-12 46.9 0.1 5.1e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG81759.1 - 4.7e-05 23.5 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG81759.1 - 0.0097 16.1 0.1 0.046 13.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain FAM60A PF15396.6 GBG81760.1 - 4.5 7.2 8.2 5.1 7.0 8.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A NPR3 PF03666.13 GBG81760.1 - 8.2 5.1 19.1 9.2 4.9 19.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PsbQ PF05757.11 GBG81761.1 - 1.7e-58 197.6 2.2 1.7e-58 197.6 2.2 1.7 1 1 1 2 2 2 1 Oxygen evolving enhancer protein 3 (PsbQ) MIT PF04212.18 GBG81761.1 - 0.018 15.1 0.6 0.84 9.8 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF4327 PF14217.6 GBG81761.1 - 0.027 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) Tmemb_14 PF03647.13 GBG81762.1 - 0.02 15.6 1.0 0.041 14.6 1.0 1.5 1 0 0 1 1 1 0 Transmembrane proteins 14C PTH2 PF01981.16 GBG81763.1 - 1.3e-45 154.4 0.2 1.7e-45 154.1 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Nop14 PF04147.12 GBG81764.1 - 0.038 12.2 10.9 0.044 12.0 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG81764.1 - 0.098 12.1 12.4 0.12 11.8 12.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG81764.1 - 0.35 9.1 10.9 0.45 8.7 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SIR4_SID PF16991.5 GBG81764.1 - 8.2 6.5 6.8 16 5.5 6.8 1.4 1 0 0 1 1 1 0 Sir4 SID domain RVT_1 PF00078.27 GBG81766.1 - 2.2e-28 99.3 0.1 3.7e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81766.1 - 3e-25 88.1 0.0 7.7e-25 86.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81766.1 - 9.4e-24 83.7 0.0 1.9e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG81766.1 - 2.3e-06 28.1 0.0 5.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81766.1 - 1.5e-05 25.4 0.0 2.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81766.1 - 0.00048 19.9 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81766.1 - 0.0024 17.7 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG81766.1 - 0.0096 16.2 0.3 0.069 13.4 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG81766.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.3 3 0 0 3 3 3 0 Integrase zinc binding domain SMG1 PF15785.5 GBG81767.1 - 0.25 9.7 2.3 0.34 9.2 2.3 1.3 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 SURF2 PF05477.11 GBG81767.1 - 4 7.0 19.4 0.015 15.0 7.1 2.4 3 0 0 3 3 3 0 Surfeit locus protein 2 (SURF2) RVT_1 PF00078.27 GBG81768.1 - 2.9e-18 66.2 0.0 5.8e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-K PF11802.8 GBG81768.1 - 0.2 11.2 3.2 0.39 10.3 3.2 1.4 1 0 0 1 1 1 0 Centromere-associated protein K AT_hook PF02178.19 GBG81770.1 - 0.011 15.6 14.2 0.033 14.0 3.1 2.9 2 0 0 2 2 2 0 AT hook motif TcdB_toxin_midN PF12256.8 GBG81770.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DUF1639 PF07797.14 GBG81770.1 - 0.8 9.7 5.7 11 6.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) TMEM51 PF15345.6 GBG81770.1 - 5 6.9 8.4 4 7.2 6.0 2.0 1 1 0 1 1 1 0 Transmembrane protein 51 DDE_Tnp_4 PF13359.6 GBG81772.1 - 5.2e-20 71.7 0.1 1.7e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81772.1 - 1.9e-07 30.9 0.0 3.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81772.1 - 0.028 14.1 0.1 0.16 11.6 0.0 2.1 2 1 0 2 2 2 0 Transposase DDE domain DUF659 PF04937.15 GBG81773.1 - 1.3e-27 96.6 0.3 1.9e-27 96.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81773.1 - 0.0031 17.3 0.1 0.0083 15.9 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG81774.1 - 1.2e-33 115.2 0.1 2.2e-33 114.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81774.1 - 1.2e-27 96.3 0.1 2.8e-27 95.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81774.1 - 1.3e-24 87.0 0.2 3.1e-24 85.7 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG81774.1 - 4.8e-14 52.2 0.1 1.2e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG81775.1 - 0.0041 17.1 1.6 0.0075 16.3 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle CPSF73-100_C PF11718.8 GBG81775.1 - 0.61 9.6 4.4 1.2 8.7 4.4 1.6 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF2828 PF11443.8 GBG81775.1 - 1.1 7.3 11.4 1.4 6.9 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4407 PF14362.6 GBG81775.1 - 2.5 7.4 10.5 3.2 7.0 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDE_Tnp_4 PF13359.6 GBG81777.1 - 7.3e-31 107.0 0.1 3.6e-29 101.5 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG81777.1 - 7.9e-17 61.5 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG81777.1 - 0.0023 17.6 1.3 0.6 9.7 0.0 3.0 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG81777.1 - 0.086 13.2 0.8 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG81779.1 - 1.7e-07 31.5 3.1 1.1e-06 28.9 1.3 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 GBG81782.1 - 0.014 15.6 5.6 0.053 13.8 0.0 3.8 5 1 0 5 5 5 0 Retrotransposon gag protein Use1 PF09753.9 GBG81782.1 - 0.054 13.2 6.0 0.11 12.1 6.0 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF2383 PF09537.10 GBG81782.1 - 0.077 13.3 0.1 7.1 7.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Plexin_cytopl PF08337.12 GBG81782.1 - 0.13 10.9 2.0 0.081 11.6 0.3 1.4 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain CLZ PF16526.5 GBG81782.1 - 1.8 9.0 4.4 2.7 8.4 0.5 3.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 GBG81782.1 - 4.7 7.7 7.5 1.1 9.7 0.2 3.3 3 1 0 3 3 3 0 Cell division protein ZapB gag-asp_proteas PF13975.6 GBG81783.1 - 3.1e-12 46.9 0.1 2.6e-10 40.7 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81783.1 - 1.1e-08 35.6 0.0 3.1e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG81783.1 - 0.0011 18.7 1.0 0.012 15.4 0.2 2.4 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG81783.1 - 0.0046 16.5 0.0 3.2 7.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 GBG81783.1 - 0.008 16.5 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease FAD_binding_4 PF01565.23 GBG81783.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Peptidase_C48 PF02902.19 GBG81784.1 - 9.8e-07 28.8 0.1 1.9e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RRM_1 PF00076.22 GBG81786.1 - 4.2e-22 77.7 0.0 7.1e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 GBG81786.1 - 1.6e-15 57.3 0.2 1.6e-15 57.3 0.2 2.4 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_7 PF16367.5 GBG81786.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif DUF4718 PF15842.5 GBG81789.1 - 0.43 10.3 4.2 0.23 11.2 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Toprim_N PF08275.11 GBG81790.1 - 0.00012 22.1 9.5 89 3.2 0.0 8.8 2 2 7 9 9 9 0 DNA primase catalytic core, N-terminal domain RTA1 PF04479.13 GBG81790.1 - 0.00075 19.2 20.7 31 4.1 0.1 9.9 4 4 7 11 11 11 0 RTA1 like protein ORF_2_N PF18492.1 GBG81790.1 - 0.00086 19.5 0.0 34 4.7 0.0 5.6 3 2 2 7 7 7 0 Open reading frame 2 N-terminal domain Methyltransf_1N PF02870.15 GBG81790.1 - 0.0037 18.1 8.0 7.6 7.4 0.2 6.2 3 2 4 7 7 7 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain PapC_C PF13953.6 GBG81790.1 - 0.063 13.1 36.0 12 5.8 0.6 10.3 1 1 9 10 10 10 0 PapC C-terminal domain DdrB PF12747.7 GBG81790.1 - 8.1 6.3 24.9 30 4.4 0.2 7.4 1 1 8 9 9 9 0 DdrB-like protein Integrase_H2C2 PF17921.1 GBG81791.1 - 9.7e-08 32.0 0.0 2.8e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RVP PF00077.20 GBG81791.1 - 0.00011 22.5 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG81791.1 - 0.00042 20.8 0.0 0.00088 19.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81791.1 - 0.0053 17.4 0.1 0.015 15.9 0.1 1.7 1 1 0 1 1 1 1 Aspartyl protease ACT_3 PF10000.9 GBG81791.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 ACT domain RTA1 PF04479.13 GBG81792.1 - 0.00041 20.0 15.4 11 5.6 0.1 8.5 3 3 7 10 10 10 4 RTA1 like protein FBA_3 PF08268.12 GBG81792.1 - 0.034 14.1 12.9 1.5 8.8 0.1 4.8 1 1 5 6 6 6 0 F-box associated domain PapC_C PF13953.6 GBG81792.1 - 0.069 13.0 42.5 5 7.0 1.7 9.7 1 1 12 13 13 13 0 PapC C-terminal domain Methyltransf_1N PF02870.15 GBG81792.1 - 0.77 10.6 6.8 89 4.0 0.0 5.6 3 3 3 6 6 6 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DdrB PF12747.7 GBG81792.1 - 0.99 9.2 25.4 33 4.3 0.2 7.9 1 1 8 9 9 9 0 DdrB-like protein RT_RNaseH_2 PF17919.1 GBG81793.1 - 8.4e-31 106.0 0.1 1.6e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81793.1 - 1.8e-19 70.0 0.0 3.8e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81793.1 - 2.8e-19 69.5 0.0 5e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81793.1 - 1.1e-15 57.9 0.0 3.3e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG81793.1 - 0.032 14.5 0.4 0.28 11.5 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Chromo PF00385.24 GBG81793.1 - 0.033 14.1 0.0 0.64 10.0 0.0 2.6 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC_3 PF13917.6 GBG81793.1 - 0.063 13.2 3.0 0.14 12.2 3.0 1.5 1 0 0 1 1 1 0 Zinc knuckle DAPDH_C PF16654.5 GBG81793.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain RVT_1 PF00078.27 GBG81794.1 - 1.1e-26 93.7 0.1 1.9e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LptF_LptG PF03739.14 GBG81794.1 - 4.8e-22 78.3 0.0 1.7e-21 76.5 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG rve PF00665.26 GBG81794.1 - 1.5e-13 51.0 0.0 3.6e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain WhiA_N PF10298.9 GBG81795.1 - 0.034 14.2 0.6 3.8 7.6 0.1 2.5 1 1 2 3 3 3 0 WhiA N-terminal LAGLIDADG-like domain ParD_antitoxin PF03693.14 GBG81795.1 - 1.6 9.2 6.9 1.1e+02 3.4 0.2 4.6 2 1 3 5 5 5 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH SeqA_N PF17206.3 GBG81795.1 - 2.4 7.5 18.0 37 3.7 0.0 6.2 6 0 0 6 6 6 0 SeqA protein N-terminal domain Myc-LZ PF02344.15 GBG81795.1 - 6.6 6.9 18.7 2.7 8.1 0.1 5.5 4 1 3 7 7 7 0 Myc leucine zipper domain WW PF00397.26 GBG81797.1 - 0.0089 16.1 0.9 0.0089 16.1 0.9 2.1 2 0 0 2 2 2 1 WW domain RVT_1 PF00078.27 GBG81798.1 - 8.5e-36 123.5 0.1 1.7e-35 122.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81798.1 - 2e-21 76.3 0.2 6.4e-21 74.6 0.2 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81798.1 - 3.7e-18 65.4 1.1 7.8e-18 64.3 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG81798.1 - 4.3e-12 45.9 0.0 1.6e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81798.1 - 4.1e-11 43.1 0.0 1.3e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG81798.1 - 2.2e-08 34.0 0.0 4.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81798.1 - 0.00045 20.8 0.0 0.0011 19.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81798.1 - 0.0012 19.4 0.0 0.0031 18.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG81798.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG81798.1 - 0.027 14.7 1.2 0.054 13.7 0.2 2.1 2 0 0 2 2 2 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG81798.1 - 0.18 11.4 0.1 0.18 11.4 0.1 2.6 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG81799.1 - 6.7e-27 93.5 0.0 2e-26 91.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81799.1 - 9e-24 83.8 0.1 2.6e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81799.1 - 3.1e-19 69.4 0.0 1.5e-18 67.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG81799.1 - 0.0017 18.9 0.0 0.0088 16.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81799.1 - 0.015 15.9 0.0 0.042 14.5 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG81799.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Aspartyl protease Casc1_N PF15927.5 GBG81799.1 - 0.15 11.7 7.4 0.38 10.4 7.4 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus HSF_DNA-bind PF00447.17 GBG81800.1 - 5.2e-31 107.1 0.3 1.3e-30 105.9 0.3 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding DUF659 PF04937.15 GBG81801.1 - 2.7e-25 89.0 0.4 4.3e-25 88.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RET_CLD3 PF17812.1 GBG81801.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 RET Cadherin like domain 3 oligo_HPY PF08352.12 GBG81802.1 - 0.11 13.1 0.0 2.6 8.6 0.0 2.9 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Rad21_Rec8_N PF04825.13 GBG81803.1 - 1.8e-38 131.1 0.0 3.8e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GBG81803.1 - 8.2e-19 66.6 0.0 2.3e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein PRP21_like_P PF12230.8 GBG81804.1 - 2.5e-46 158.3 42.7 1.7e-26 93.4 6.3 2.9 1 1 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 GBG81804.1 - 6.5e-38 128.5 1.7 6.5e-19 67.7 0.3 2.4 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 GBG81804.1 - 4.6e-12 45.5 0.0 9.9e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family CDC45 PF02724.14 GBG81804.1 - 0.0037 15.6 17.8 0.0059 15.0 17.8 1.3 1 0 0 1 1 1 1 CDC45-like protein Pox_Ag35 PF03286.14 GBG81804.1 - 1.7 8.4 16.8 6.7 6.4 16.8 2.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_Rpc4 PF05132.14 GBG81804.1 - 2.8 8.4 16.0 15 6.0 16.0 2.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 GBG81804.1 - 3.6 6.3 13.2 6 5.5 13.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIP PF07454.11 GBG81804.1 - 3.9 6.8 14.7 89 2.4 16.1 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TFIIF_alpha PF05793.12 GBG81804.1 - 7.6 5.0 34.3 15 4.0 34.3 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ABC_tran PF00005.27 GBG81806.1 - 9.1e-21 74.8 0.0 3.9e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 GBG81806.1 - 1.3e-20 73.7 16.4 2.6e-12 46.6 3.5 2.3 1 1 1 2 2 2 2 ABC-2 type transporter Asp_protease_2 PF13650.6 GBG81806.1 - 2.8e-07 31.1 0.0 1.1e-06 29.2 0.0 2.1 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81806.1 - 9.3e-06 26.1 0.0 3.1e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81806.1 - 4.3e-05 23.3 0.0 8.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease AAA_21 PF13304.6 GBG81806.1 - 0.00061 19.7 0.0 0.55 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Retrotrans_gag PF03732.17 GBG81806.1 - 0.0013 19.0 1.7 0.0035 17.6 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein RsgA_GTPase PF03193.16 GBG81806.1 - 0.0022 17.9 0.1 0.0057 16.6 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase Asp_protease PF09668.10 GBG81806.1 - 0.0024 17.7 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease AAA_29 PF13555.6 GBG81806.1 - 0.0041 16.8 0.3 0.0095 15.7 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain XFP_C PF09363.10 GBG81806.1 - 0.04 13.4 0.1 42 3.5 0.0 3.4 3 0 0 3 3 3 0 XFP C-terminal domain AAA_25 PF13481.6 GBG81806.1 - 0.043 13.4 0.0 0.17 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GBG81806.1 - 0.43 10.9 0.0 0.43 10.9 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain AAA_33 PF13671.6 GBG81806.1 - 0.46 10.6 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GBG81806.1 - 7.3 7.0 6.3 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 GBG81808.1 - 7.3e-21 74.6 8.8 7.3e-21 74.6 8.8 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 GBG81808.1 - 3.2e-05 23.2 5.7 0.00015 21.0 5.7 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein PDR_assoc PF08370.11 GBG81808.1 - 0.0029 17.3 1.0 0.0029 17.3 1.0 1.7 2 0 0 2 2 2 1 Plant PDR ABC transporter associated PDR_CDR PF06422.12 GBG81808.1 - 0.11 12.4 1.7 1 9.3 0.1 2.3 2 0 0 2 2 2 0 CDR ABC transporter ABC2_membrane_2 PF12679.7 GBG81808.1 - 0.42 9.9 5.4 0.9 8.8 5.4 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein RT_RNaseH_2 PF17919.1 GBG81809.1 - 3.5e-33 113.6 0.1 6.4e-33 112.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81809.1 - 4.6e-29 100.8 0.1 9.3e-29 99.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81809.1 - 2.9e-20 72.1 0.1 6.7e-20 70.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG81809.1 - 1.7e-19 70.2 0.0 3.4e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81809.1 - 9.4e-14 51.6 0.0 2.3e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81809.1 - 7.1e-06 26.5 0.0 3.7e-05 24.2 0.0 2.2 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81809.1 - 0.0014 19.2 0.0 0.0034 18.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG81809.1 - 0.0016 18.6 0.0 0.0043 17.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 GBG81809.1 - 0.0022 17.8 0.0 0.0059 16.4 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG81809.1 - 0.023 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF2862 PF11061.8 GBG81809.1 - 0.13 12.1 0.0 0.44 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) Asp_protease PF09668.10 GBG81809.1 - 0.18 11.6 0.1 0.55 10.0 0.1 1.9 1 1 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG81810.1 - 4e-27 95.2 0.3 9.8e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81810.1 - 1.9e-11 43.8 0.0 5.8e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG81810.1 - 6.5e-11 42.0 0.0 1.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG81810.1 - 7.8e-07 29.3 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ABC2_membrane PF01061.24 GBG81810.1 - 7.7e-06 25.5 1.5 1.2e-05 24.9 1.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GBG81810.1 - 0.024 15.1 0.0 0.068 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Nop14 PF04147.12 GBG81812.1 - 0.2 9.8 30.0 0.24 9.6 30.0 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG81812.1 - 1 7.8 39.9 1.3 7.5 39.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3408 PF11888.8 GBG81812.1 - 4 7.6 17.2 1.5 8.9 9.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) BUD22 PF09073.10 GBG81812.1 - 5.2 6.3 26.7 7.2 5.8 26.7 1.2 1 0 0 1 1 1 0 BUD22 CIA30 PF08547.12 GBG81816.1 - 2.4e-33 115.4 0.0 2.8e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NOA36 PF06524.12 GBG81817.1 - 0.035 13.5 20.5 0.053 12.8 20.5 1.3 1 0 0 1 1 1 0 NOA36 protein Voldacs PF03517.13 GBG81817.1 - 0.16 12.0 11.2 0.19 11.8 11.2 1.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Mito_carr PF00153.27 GBG81818.1 - 0.022 14.7 0.1 0.075 13.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial carrier protein FAM199X PF15814.5 GBG81818.1 - 0.6 9.1 8.9 1 8.4 8.9 1.3 1 0 0 1 1 1 0 Protein family FAM199X Methyltransf_25 PF13649.6 GBG81820.1 - 4.2e-36 123.5 0.1 2.6e-20 72.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GBG81820.1 - 6e-34 116.6 0.1 3.7e-18 65.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GBG81820.1 - 3.3e-30 104.9 0.4 2.6e-18 66.2 0.1 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GBG81820.1 - 3.7e-25 88.7 0.0 5.4e-18 65.4 0.0 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GBG81820.1 - 5.6e-24 84.8 0.1 6.9e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 GBG81820.1 - 2.3e-15 56.6 0.0 1.2e-13 51.0 0.0 2.2 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 GBG81820.1 - 9.3e-13 48.0 0.0 1.5e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 GBG81820.1 - 7e-10 38.8 0.5 1.5e-07 31.2 0.0 2.4 2 1 1 3 3 3 1 AdoMet dependent proline di-methyltransferase NodS PF05401.11 GBG81820.1 - 1.8e-09 37.5 0.0 1.3e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) TehB PF03848.14 GBG81820.1 - 3.7e-09 36.3 0.0 1.7e-05 24.3 0.0 2.5 2 1 0 2 2 2 2 Tellurite resistance protein TehB CheR PF01739.18 GBG81820.1 - 4.4e-09 36.1 0.1 0.002 17.7 0.0 3.2 2 1 1 3 3 3 2 CheR methyltransferase, SAM binding domain MTS PF05175.14 GBG81820.1 - 1.1e-08 34.8 0.0 0.0013 18.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain PCMT PF01135.19 GBG81820.1 - 5.3e-08 32.9 0.0 2.5e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 GBG81820.1 - 4.1e-06 26.0 0.1 0.00061 18.8 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 GBG81820.1 - 1.4e-05 24.5 0.2 0.0053 16.1 0.0 2.2 1 1 1 2 2 2 2 O-methyltransferase domain Methyltransf_32 PF13679.6 GBG81820.1 - 2e-05 24.6 0.0 0.2 11.7 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain RrnaAD PF00398.20 GBG81820.1 - 2.7e-05 23.4 0.0 0.014 14.5 0.0 2.3 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase MetW PF07021.12 GBG81820.1 - 6.4e-05 22.6 0.0 0.00018 21.2 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 GBG81820.1 - 9.8e-05 21.9 0.5 0.16 11.4 0.0 2.5 3 0 0 3 3 3 2 Putative methyltransferase Methyltransf_16 PF10294.9 GBG81820.1 - 0.00012 21.9 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 GBG81820.1 - 0.00013 21.5 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 GBG81820.1 - 0.00036 19.7 0.0 0.07 12.2 0.0 2.3 2 0 0 2 2 2 1 DREV methyltransferase DOT1 PF08123.13 GBG81820.1 - 0.0013 18.3 0.3 0.026 14.0 0.0 2.7 1 1 1 2 2 2 1 Histone methylation protein DOT1 FtsJ PF01728.19 GBG81820.1 - 0.0035 17.5 0.0 4 7.5 0.0 2.6 2 1 0 2 2 2 2 FtsJ-like methyltransferase Met_10 PF02475.16 GBG81820.1 - 0.0041 16.9 0.0 0.054 13.2 0.0 2.2 2 0 0 2 2 2 1 Met-10+ like-protein TPMT PF05724.11 GBG81820.1 - 0.011 15.4 0.0 0.39 10.3 0.0 2.6 2 1 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_15 PF09445.10 GBG81820.1 - 0.018 14.6 2.5 0.32 10.6 0.1 2.7 3 0 0 3 3 3 0 RNA cap guanine-N2 methyltransferase Rsm22 PF09243.10 GBG81820.1 - 0.083 12.1 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 RRM_1 PF00076.22 GBG81821.1 - 3.2e-22 78.1 0.0 4.1e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG81821.1 - 0.0027 17.8 0.0 0.0065 16.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif Seipin PF06775.14 GBG81824.1 - 3.8e-39 134.8 0.0 7.7e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF2649 PF10854.8 GBG81824.1 - 0.74 10.2 5.4 1.9 8.9 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) Sporozoite_P67 PF05642.11 GBG81824.1 - 6.7 4.7 11.1 0.55 8.3 6.3 1.6 2 0 0 2 2 2 0 Sporozoite P67 surface antigen LpxB PF02684.15 GBG81826.1 - 3.5e-23 82.1 0.0 4.2e-22 78.5 0.0 2.0 2 0 0 2 2 2 2 Lipid-A-disaccharide synthetase AAA_12 PF13087.6 GBG81827.1 - 4.1e-43 147.3 0.0 6.5e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG81827.1 - 3.7e-25 89.2 0.3 2.7e-14 53.6 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GBG81827.1 - 2.2e-12 47.1 0.0 5.3e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG81827.1 - 1.9e-06 28.3 0.0 8e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GBG81827.1 - 0.0042 16.6 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 GBG81827.1 - 0.053 13.8 0.1 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG81827.1 - 0.088 12.4 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 GBG81827.1 - 0.095 12.2 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 GBG81827.1 - 0.2 12.0 0.0 0.49 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Aldo_ket_red PF00248.21 GBG81829.1 - 2.2e-64 217.5 0.0 4.6e-42 144.2 0.0 2.3 2 1 0 2 2 2 2 Aldo/keto reductase family DUF3246 PF11596.8 GBG81829.1 - 0.003 17.0 7.1 0.0048 16.4 7.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) SR-25 PF10500.9 GBG81829.1 - 0.029 14.0 11.0 0.044 13.4 11.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5451 PF17532.2 GBG81829.1 - 0.075 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5451) NOA36 PF06524.12 GBG81829.1 - 0.5 9.6 8.7 0.77 9.0 8.7 1.2 1 0 0 1 1 1 0 NOA36 protein NAM-associated PF14303.6 GBG81829.1 - 0.82 10.4 4.2 1.3 9.8 4.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain UPF0560 PF10577.9 GBG81829.1 - 1.7 7.0 6.0 2.4 6.6 6.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Chorion_2 PF03964.15 GBG81829.1 - 2.3 9.1 11.3 6.2 7.7 11.3 1.7 1 0 0 1 1 1 0 Chorion family 2 Cwf_Cwc_15 PF04889.12 GBG81829.1 - 5.9 6.5 14.3 9.2 5.9 14.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2076 PF09849.9 GBG81829.1 - 6.2 6.8 9.1 11 6.0 9.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF515 PF04415.12 GBG81829.1 - 8.7 4.6 7.5 14 4.0 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Hist_deacetyl PF00850.19 GBG81830.1 - 1.6e-76 257.7 0.0 2.4e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Macoilin PF09726.9 GBG81830.1 - 0.081 11.5 16.9 0.13 10.8 16.9 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 GBG81830.1 - 0.18 10.6 20.6 0.29 9.9 20.6 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 GBG81830.1 - 1.3 8.1 28.8 1.9 7.6 28.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 GBG81830.1 - 2.1 8.2 27.4 3.2 7.6 27.4 1.2 1 0 0 1 1 1 0 SPX domain PAP1 PF08601.10 GBG81830.1 - 5.8 6.5 31.6 8.8 5.9 31.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Peptidase_S64 PF08192.11 GBG81830.1 - 8.6 4.7 17.3 12 4.3 17.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 UMP1 PF05348.11 GBG81831.1 - 3.4e-29 101.4 0.1 3.8e-29 101.3 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 RT_RNaseH PF17917.1 GBG81832.1 - 9.2e-22 77.3 0.0 2e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81832.1 - 9.2e-21 73.8 0.0 1.9e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81832.1 - 1.4e-13 51.1 0.0 2.9e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81832.1 - 1.2e-06 29.0 0.2 4.9e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81832.1 - 2.1e-05 25.1 0.0 9.1e-05 23.0 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG81832.1 - 0.015 15.1 1.1 0.029 14.2 1.1 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG81832.1 - 0.07 13.5 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1421 PF07223.11 GBG81833.1 - 0.41 10.5 1.0 4.3 7.3 0.1 3.2 3 0 0 3 3 3 0 UBA-like domain (DUF1421) DUF22 PF01629.16 GBG81833.1 - 0.69 9.6 2.4 15 5.4 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function DUF22 Transformer PF06495.11 GBG81833.1 - 2.4 8.2 15.5 5.3 7.1 15.5 1.5 1 0 0 1 1 1 0 Fruit fly transformer protein FAD_binding_3 PF01494.19 GBG81834.1 - 2.1e-05 23.9 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF659 PF04937.15 GBG81835.1 - 1.7e-05 24.7 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG81835.1 - 0.017 15.2 2.3 0.14 12.3 0.4 2.5 2 0 0 2 2 2 0 Integrase zinc binding domain NDUF_B12 PF08122.12 GBG81835.1 - 0.06 13.4 0.3 0.16 12.1 0.3 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family SseC PF04888.12 GBG81835.1 - 0.45 10.1 2.5 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family FAD_binding_3 PF01494.19 GBG81836.1 - 3.3e-10 39.8 0.0 1.2e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 GBG81836.1 - 1.1e-05 24.6 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pkinase PF00069.25 GBG81837.1 - 1.3e-22 80.4 0.0 1.5e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG81837.1 - 1.4e-18 67.2 0.0 1.5e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GBG81837.1 - 0.0048 15.9 0.0 0.0053 15.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GBG81837.1 - 0.094 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 GBG81837.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 GBG81838.1 - 3e-20 72.1 7.7 2.2e-06 28.3 0.5 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG81838.1 - 1.7e-06 28.2 0.0 0.066 13.5 0.0 3.8 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 GBG81838.1 - 0.00042 19.7 0.0 0.54 9.5 0.0 2.4 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 GBG81838.1 - 4.5 7.9 9.7 12 6.5 0.2 4.0 4 0 0 4 4 4 0 PQQ-like domain FA_hydroxylase PF04116.13 GBG81839.1 - 2.5e-16 60.3 16.2 4.2e-16 59.5 16.2 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Retrotrans_gag PF03732.17 GBG81842.1 - 0.027 14.7 5.6 4.7 7.6 0.0 4.1 4 1 0 4 4 4 0 Retrotransposon gag protein DUF4404 PF14357.6 GBG81842.1 - 0.21 12.2 0.3 0.21 12.2 0.3 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) Use1 PF09753.9 GBG81842.1 - 0.23 11.2 12.4 0.043 13.5 8.9 1.5 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF572 PF04502.13 GBG81842.1 - 0.58 9.7 10.6 0.74 9.4 10.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Sulfatase_C PF14707.6 GBG81842.1 - 1.2 9.9 5.5 0.42 11.4 0.8 2.4 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase AIF-MLS PF14962.6 GBG81842.1 - 7 6.6 11.9 2.6 8.0 9.0 1.6 1 1 1 2 2 2 0 Mitochondria Localisation Sequence BUD22 PF09073.10 GBG81844.1 - 1.2 8.4 16.8 1.5 8.0 16.8 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG81844.1 - 2 7.8 18.6 2.7 7.3 18.6 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG81844.1 - 3.5 5.7 20.8 4.6 5.3 20.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG81844.1 - 5.1 5.3 15.7 6.8 4.8 15.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 GBG81844.1 - 7.7 5.7 8.6 11 5.2 8.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Pkinase_Tyr PF07714.17 GBG81846.1 - 9.6e-39 133.2 0.0 3.3e-38 131.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG81846.1 - 2.8e-37 128.5 0.0 4.2e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG81846.1 - 0.0079 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GBG81847.1 - 2e-39 135.5 0.0 9.5e-39 133.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG81847.1 - 1.2e-36 126.4 0.0 1.9e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG81847.1 - 0.033 14.1 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ_3 PF13570.6 GBG81847.1 - 3.4 8.3 6.9 2.7 8.6 1.1 3.3 3 0 0 3 3 3 0 PQQ-like domain Pkinase_Tyr PF07714.17 GBG81849.1 - 7.9e-26 90.9 0.0 6e-25 88.0 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG81849.1 - 6.7e-21 74.8 0.0 1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 GBG81850.1 - 2.5e-18 66.4 0.0 6.2e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG81850.1 - 3.2e-18 66.0 0.1 8.6e-16 58.0 0.0 3.1 1 1 1 2 2 2 1 Protein tyrosine kinase PQQ_3 PF13570.6 GBG81850.1 - 0.99 10.0 4.4 4.7 7.8 0.8 3.3 3 0 0 3 3 3 0 PQQ-like domain RT_RNaseH PF17917.1 GBG81853.1 - 4e-19 68.8 0.0 1.1e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81853.1 - 1.2e-18 67.0 0.0 2.6e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PriC PF07445.12 GBG81853.1 - 0.072 13.0 3.3 0.15 11.9 3.3 1.4 1 0 0 1 1 1 0 Primosomal replication protein priC THOC7 PF05615.13 GBG81853.1 - 0.099 12.9 4.5 0.47 10.7 0.6 2.8 2 0 0 2 2 2 0 Tho complex subunit 7 Pkinase_Tyr PF07714.17 GBG81854.1 - 8.2e-40 136.7 0.0 4.5e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG81854.1 - 4.4e-36 124.6 0.0 2.8e-18 66.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG81854.1 - 0.00012 22.0 0.6 0.17 11.8 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG81854.1 - 0.0089 14.8 0.2 0.31 9.8 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase F-box-like PF12937.7 GBG81855.1 - 3.8e-06 26.7 0.6 8.5e-06 25.6 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG81855.1 - 6.5e-06 25.9 0.2 1.7e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 GBG81855.1 - 0.00023 21.5 2.4 0.2 12.1 0.4 3.6 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG81855.1 - 0.0083 15.9 0.7 0.025 14.4 0.3 1.9 2 0 0 2 2 2 1 Leucine rich repeat F-box_5 PF18511.1 GBG81855.1 - 0.032 13.8 0.1 0.077 12.6 0.1 1.6 1 0 0 1 1 1 0 F-box LRR_6 PF13516.6 GBG81855.1 - 3.2 8.1 8.4 12 6.2 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeat ORC6 PF05460.13 GBG81857.1 - 0.18 11.0 2.0 1.5 8.0 2.7 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Peptidase_C48 PF02902.19 GBG81858.1 - 1.6e-06 28.1 2.1 1.6e-06 28.1 2.1 1.6 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Pneumo_att_G PF05539.11 GBG81858.1 - 1.6 8.3 11.5 3.4 7.2 11.5 1.5 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Zip PF02535.22 GBG81858.1 - 3.4 6.8 7.9 5.9 6.0 7.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF659 PF04937.15 GBG81859.1 - 7.9e-17 61.5 0.0 1.4e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81859.1 - 3.7e-05 23.4 0.1 8.2e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase_Tyr PF07714.17 GBG81860.1 - 9.7e-39 133.2 0.0 2.1e-37 128.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG81860.1 - 8.5e-36 123.7 0.0 1.3e-35 123.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG81860.1 - 0.0038 17.2 0.1 0.0067 16.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF659 PF04937.15 GBG81861.1 - 4e-12 46.3 0.0 6.1e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF150 PF02576.17 GBG81861.1 - 2.1 8.8 5.4 19 5.8 0.6 3.2 1 1 1 2 2 2 0 RimP N-terminal domain RXT2_N PF08595.11 GBG81861.1 - 5.1 7.1 9.5 11 6.0 9.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal RT_RNaseH PF17917.1 GBG81862.1 - 4.8e-20 71.8 0.0 9.7e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81862.1 - 7.2e-19 67.7 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81862.1 - 3.9e-12 46.1 0.1 8.8e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81862.1 - 1.1e-06 28.9 0.0 2.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81862.1 - 1.6e-06 28.6 0.0 3.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81862.1 - 0.0011 19.6 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG81862.1 - 0.0017 18.2 0.8 0.003 17.3 0.8 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG81862.1 - 0.17 12.2 0.0 0.5 10.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG81863.1 - 8.4e-24 83.5 0.0 2e-22 79.1 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81863.1 - 1.1e-22 80.3 0.0 2.7e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG81863.1 - 4.6e-06 26.4 0.0 8.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81863.1 - 2e-05 25.2 0.0 4.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81863.1 - 0.0011 19.4 0.0 0.0038 17.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG81863.1 - 0.019 15.2 0.0 0.073 13.4 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG81863.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Integrin_b_cyt PF08725.11 GBG81863.1 - 0.11 12.1 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain TSSC4 PF15264.6 GBG81864.1 - 2.8e-08 34.1 0.4 1.4e-07 31.8 0.4 2.2 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 Peptidase_C48 PF02902.19 GBG81865.1 - 1e-10 41.8 0.6 1.5e-10 41.3 0.6 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AAA_16 PF13191.6 GBG81865.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF4360 PF14273.6 GBG81866.1 - 3.5e-41 141.0 1.6 4e-41 140.8 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81867.1 - 3e-45 154.3 0.2 3.5e-45 154.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Nop14 PF04147.12 GBG81868.1 - 0.33 9.1 49.1 0.44 8.7 49.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4360 PF14273.6 GBG81869.1 - 5.8e-40 137.1 1.6 8.2e-40 136.6 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Peptidase_C48 PF02902.19 GBG81870.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4360 PF14273.6 GBG81873.1 - 1.2e-41 142.5 1.9 1.4e-41 142.3 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81875.1 - 2.9e-41 141.3 1.7 3.3e-41 141.1 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81876.1 - 2.9e-37 128.2 0.0 3.4e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DIM PF08194.12 GBG81876.1 - 0.19 12.0 1.0 0.35 11.1 1.0 1.5 1 0 0 1 1 1 0 DIM protein DUF4360 PF14273.6 GBG81877.1 - 1.7e-37 129.0 0.6 2.1e-37 128.7 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81878.1 - 4.9e-38 130.8 0.0 5.5e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81879.1 - 4.5e-36 124.4 0.0 6.8e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG81879.1 - 3.7e-30 103.9 0.0 1.5e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81879.1 - 1.4e-18 67.1 0.0 3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81879.1 - 9.4e-12 44.9 0.1 1.4e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG81879.1 - 1.5e-10 40.8 0.0 3.2e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG81879.1 - 1.1e-06 28.9 0.0 3.5e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DUF4360 PF14273.6 GBG81880.1 - 5.9e-38 130.5 0.9 7.2e-38 130.2 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF237 PF03072.14 GBG81880.1 - 0.039 14.0 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF237) DUF4360 PF14273.6 GBG81881.1 - 3e-37 128.2 0.0 3.5e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG81882.1 - 2.1e-40 138.5 0.0 2.4e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Surface_antigen PF11054.8 GBG81882.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen Pkinase_Tyr PF07714.17 GBG81885.1 - 1e-31 110.2 0.0 4.3e-31 108.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG81885.1 - 1.2e-28 100.3 0.0 1.8e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG81885.1 - 0.00038 20.5 0.0 0.002 18.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF4834 PF16118.5 GBG81885.1 - 0.0055 17.6 0.4 0.91 10.5 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4834) Pkinase_fungal PF17667.1 GBG81885.1 - 0.0091 14.8 0.1 0.77 8.5 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase CDC45 PF02724.14 GBG81885.1 - 0.044 12.1 9.6 0.061 11.6 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 GBG81885.1 - 0.054 13.2 1.1 0.095 12.4 1.1 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH OppC_N PF12911.7 GBG81885.1 - 0.075 13.0 1.6 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C TMEM223 PF14640.6 GBG81885.1 - 0.13 12.4 0.0 0.63 10.2 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 223 RXT2_N PF08595.11 GBG81885.1 - 0.14 12.1 4.2 7.7 6.5 7.9 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Nop14 PF04147.12 GBG81885.1 - 0.29 9.3 13.0 0.42 8.8 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family XAP5 PF04921.14 GBG81885.1 - 0.5 10.2 9.6 1.1 9.0 9.6 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator SDA1 PF05285.12 GBG81885.1 - 0.93 8.9 16.0 1.6 8.1 16.0 1.3 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 GBG81885.1 - 1.3 8.7 9.6 3.5 7.3 9.6 1.7 1 0 0 1 1 1 0 FAM176 family U79_P34 PF03064.16 GBG81885.1 - 2.9 7.2 10.1 6.8 6.0 10.1 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RNA_polI_A34 PF08208.11 GBG81885.1 - 8 6.5 12.3 12 5.9 9.7 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 NOA36 PF06524.12 GBG81885.1 - 8.3 5.6 11.7 13 5.0 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 GBG81885.1 - 8.5 6.3 10.3 17 5.3 10.3 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF659 PF04937.15 GBG81886.1 - 2.1e-19 69.9 0.0 3.1e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG81887.1 - 3.3e-08 33.5 0.1 7.4e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG81888.1 - 5e-11 42.8 0.0 1.3e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Vma12 PF11712.8 GBG81888.1 - 0.012 15.7 1.5 1.5 8.8 0.1 2.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Vma12 PF11712.8 GBG81889.1 - 0.11 12.5 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PIF1 PF05970.14 GBG81891.1 - 4.2e-67 226.9 0.0 6.3e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase RT_RNaseH_2 PF17919.1 GBG81891.1 - 2e-24 85.5 0.0 4.7e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81891.1 - 5.3e-19 68.1 0.1 1.2e-18 66.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81891.1 - 2.2e-14 53.7 0.0 7.6e-14 51.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG81891.1 - 4e-13 49.6 0.1 9.7e-11 41.9 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81891.1 - 7.9e-12 45.2 0.1 1.8e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_30 PF13604.6 GBG81891.1 - 4.1e-08 33.2 0.0 8.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TFIIB PF00382.19 GBG81891.1 - 6.1e-07 29.4 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIIB repeat AAA_19 PF13245.6 GBG81891.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-H2C2 PF09337.10 GBG81891.1 - 0.091 13.0 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG81892.1 - 9.5e-27 93.9 0.0 1.6e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81892.1 - 1.1e-15 57.8 0.0 2.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81892.1 - 1.1e-13 51.1 0.0 2.9e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG81892.1 - 3.2e-09 37.2 0.0 6.6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81892.1 - 1.2e-07 32.3 0.0 2.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG81892.1 - 5.6e-07 29.8 0.1 1.6e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Asp_protease PF09668.10 GBG81892.1 - 0.00081 19.2 0.1 0.0015 18.3 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG81892.1 - 0.003 17.4 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.20 GBG81892.1 - 0.0051 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Tudor-knot PF11717.8 GBG81892.1 - 0.0077 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RVT_1 PF00078.27 GBG81893.1 - 2.3e-27 96.0 0.1 3.5e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81893.1 - 1.8e-26 92.1 0.0 7.1e-26 90.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81893.1 - 2.3e-24 85.7 0.0 8.5e-24 83.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG81893.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 GBG81893.1 - 0.059 13.6 0.0 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain RVT_1 PF00078.27 GBG81895.1 - 3e-27 95.6 0.2 1.4e-26 93.4 0.3 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG81895.1 - 8.5e-08 31.9 4.7 1.3e-07 31.4 3.1 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG81895.1 - 0.00054 19.7 1.4 0.00054 19.7 1.4 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG81895.1 - 0.0047 16.7 2.4 0.015 15.1 2.4 2.0 1 0 0 1 1 1 1 Zinc knuckle HIP1_clath_bdg PF16515.5 GBG81895.1 - 0.0052 17.4 3.4 0.0052 17.4 3.4 4.5 5 1 0 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-CCHC_4 PF14392.6 GBG81895.1 - 0.097 12.4 1.0 0.2 11.4 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle NPV_P10 PF05531.12 GBG81895.1 - 0.31 11.5 2.1 1.6 9.3 0.1 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TFIIF_alpha PF05793.12 GBG81895.1 - 1.5 7.3 23.8 2.7 6.5 23.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Dimer_Tnp_hAT PF05699.14 GBG81896.1 - 9e-10 38.2 0.2 1.8e-09 37.2 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Integrase_H2C2 PF17921.1 GBG81897.1 - 1.6e-16 60.1 1.5 2.2e-16 59.7 0.4 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG81897.1 - 3e-10 40.3 0.0 8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG81897.1 - 0.00082 19.2 0.0 0.0031 17.4 0.0 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG81897.1 - 0.0016 18.6 0.1 0.0037 17.5 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG81898.1 - 1.8e-34 119.2 0.0 2.7e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81898.1 - 8e-30 103.2 0.0 1.6e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81898.1 - 2.2e-29 101.4 0.0 4.7e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81899.1 - 2e-27 96.2 0.0 4.3e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81899.1 - 1e-21 76.8 0.0 2.4e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81899.1 - 7.3e-21 74.4 0.0 1.5e-19 70.2 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG81899.1 - 1.2e-07 32.2 0.0 2.9e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81899.1 - 4.4e-06 27.2 0.0 1.1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81899.1 - 0.00034 20.4 0.0 0.00082 19.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81899.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG81899.1 - 0.0037 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain CENP-K PF11802.8 GBG81899.1 - 0.0051 16.4 3.5 0.011 15.4 3.5 1.4 1 0 0 1 1 1 1 Centromere-associated protein K Chromo PF00385.24 GBG81899.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG81900.1 - 1.5e-27 96.5 0.0 3.6e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81900.1 - 8.5e-22 77.1 0.0 2.1e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81900.1 - 5.1e-21 74.9 0.0 1.3e-19 70.4 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG81900.1 - 1.1e-07 32.4 0.0 2.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81900.1 - 3.7e-06 27.4 0.0 8.9e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81900.1 - 0.00027 20.7 0.0 0.00069 19.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81900.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG81900.1 - 0.0032 17.6 0.0 0.0097 16.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain CENP-K PF11802.8 GBG81900.1 - 0.0047 16.5 3.5 0.0088 15.6 3.5 1.3 1 0 0 1 1 1 1 Centromere-associated protein K Chromo PF00385.24 GBG81900.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF3499 PF12005.8 GBG81900.1 - 2.2 8.9 11.3 0.3 11.7 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) RT_RNaseH_2 PF17919.1 GBG81901.1 - 1.4e-44 150.2 0.0 6e-28 96.8 0.0 3.9 2 1 1 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81901.1 - 4e-44 149.2 1.2 3.1e-27 94.9 0.0 4.0 2 1 1 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81901.1 - 8.4e-34 115.5 3.7 5.6e-17 61.6 0.1 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG81901.1 - 1.7e-26 93.1 0.1 3.5e-26 92.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG81901.1 - 4.7e-08 32.9 0.0 1.5e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG81901.1 - 2.1e-07 31.1 0.0 1.1e-06 28.9 0.0 2.2 1 1 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG81901.1 - 8.5e-05 22.7 0.2 0.064 13.5 0.1 3.0 2 0 0 2 2 2 2 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG81901.1 - 0.00032 21.3 0.0 0.0021 18.7 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81901.1 - 0.004 17.7 0.0 0.063 13.8 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1664 PF07889.12 GBG81901.1 - 0.0081 16.2 0.8 0.0081 16.2 0.8 4.0 5 0 0 5 5 5 1 Protein of unknown function (DUF1664) Asp_protease PF09668.10 GBG81901.1 - 0.026 14.3 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease HALZ PF02183.18 GBG81901.1 - 0.078 13.2 5.5 0.13 12.5 1.4 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF659 PF04937.15 GBG81903.1 - 6.7e-16 58.5 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81903.1 - 5.4e-08 32.5 0.1 1.1e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TadF PF16964.5 GBG81903.1 - 2.5 7.8 4.4 6.4 6.5 4.4 1.6 1 0 0 1 1 1 0 Putative tight adherence pilin protein F DUF659 PF04937.15 GBG81904.1 - 7e-15 55.2 0.0 1.4e-14 54.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG81905.1 - 6e-33 112.9 0.5 1.4e-31 108.5 0.0 3.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81905.1 - 6.9e-31 106.7 0.2 8.6e-30 103.1 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81905.1 - 3.2e-30 105.3 0.0 6.8e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81905.1 - 2.5e-16 59.9 0.1 6.9e-16 58.5 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG81905.1 - 1e-09 38.8 0.0 3.4e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81905.1 - 7.7e-07 29.7 0.0 2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG81905.1 - 0.00046 20.0 0.0 0.00095 19.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG81905.1 - 0.00083 19.2 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG81905.1 - 0.0016 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG81906.1 - 2.6e-26 91.6 0.1 5.7e-26 90.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81906.1 - 2.9e-19 69.5 0.0 4.6e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81906.1 - 4.5e-15 55.8 0.0 1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3863 PF12979.7 GBG81906.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) RVT_1 PF00078.27 GBG81907.1 - 9.1e-33 113.6 0.0 1.5e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribonuclease_3 PF00636.26 GBG81907.1 - 9e-27 93.8 0.9 2.7e-14 53.6 0.2 4.3 3 1 0 3 3 3 3 Ribonuclease III domain RT_RNaseH PF17917.1 GBG81907.1 - 3.1e-26 91.7 0.0 7.9e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81907.1 - 8.8e-24 83.4 0.0 2.1e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ribonucleas_3_3 PF14622.6 GBG81907.1 - 5e-17 62.3 3.3 2.4e-12 47.2 0.0 3.9 4 0 0 4 4 4 2 Ribonuclease-III-like Dicer_dimer PF03368.14 GBG81908.1 - 9.5e-24 83.4 0.1 1.8e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain PAZ PF02170.22 GBG81908.1 - 3.4e-07 30.1 0.0 6.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain dsrm PF00035.26 GBG81908.1 - 0.019 15.6 0.1 0.1 13.3 0.0 2.2 2 0 0 2 2 2 0 Double-stranded RNA binding motif RT_RNaseH_2 PF17919.1 GBG81909.1 - 2.5e-32 110.9 0.0 5.1e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81909.1 - 3.4e-29 101.2 0.2 7.7e-29 100.1 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81909.1 - 2.5e-17 62.7 0.1 5.1e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG81909.1 - 3.1e-12 46.5 0.0 6.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG81909.1 - 3.5e-09 36.9 0.0 9.8e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HAUS6_N PF14661.6 GBG81909.1 - 0.18 11.4 4.4 0.094 12.3 0.8 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus RT_RNaseH PF17917.1 GBG81910.1 - 9.1e-51 170.5 2.0 1.7e-24 86.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81910.1 - 2.1e-45 152.9 0.2 5e-26 90.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81910.1 - 2.6e-29 102.3 0.1 3.4e-17 62.7 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C PF00271.31 GBG81910.1 - 1.5e-16 60.7 0.5 5.9e-16 58.8 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RVP PF00077.20 GBG81910.1 - 0.0036 17.6 0.1 0.0088 16.3 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG81910.1 - 0.0055 17.2 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG81910.1 - 0.0056 16.5 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG81910.1 - 0.033 14.8 0.0 0.083 13.5 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG81911.1 - 2.7e-29 101.1 0.0 8.8e-29 99.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81911.1 - 1.6e-25 89.4 0.1 5.3e-25 87.7 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81911.1 - 4.1e-19 68.4 0.1 1.2e-18 66.9 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG81911.1 - 0.00034 20.8 0.0 0.00096 19.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger tRNA-synt_1_2 PF13603.6 GBG81911.1 - 0.061 12.8 0.1 0.17 11.4 0.1 1.8 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 ResIII PF04851.15 GBG81912.1 - 1.5e-15 57.6 0.1 2e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG81912.1 - 1.5e-12 47.7 0.0 2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GBG81912.1 - 2.4e-05 24.1 0.0 3.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SNF2_N PF00176.23 GBG81912.1 - 0.00024 19.9 0.1 0.00029 19.7 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 GBG81912.1 - 0.0049 17.1 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 GBG81912.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 GBG81913.1 - 2.5e-15 56.9 0.1 3.3e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GBG81913.1 - 2.5e-12 46.9 0.0 3.4e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GBG81913.1 - 6.9e-05 22.6 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SNF2_N PF00176.23 GBG81913.1 - 0.00036 19.3 0.1 0.00045 19.1 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 GBG81913.1 - 0.0072 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GBG81913.1 - 0.011 16.2 0.0 0.047 14.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RT_RNaseH PF17917.1 GBG81914.1 - 7.7e-31 106.5 0.1 2.1e-30 105.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81914.1 - 8.5e-31 106.0 0.0 4.3e-30 103.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81914.1 - 0.0026 17.3 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG81914.1 - 0.048 13.3 0.1 0.048 13.3 0.1 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Topo_Zn_Ribbon PF08272.11 GBG81916.1 - 0.026 14.2 0.2 0.026 14.2 0.2 1.8 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Asp_protease_2 PF13650.6 GBG81916.1 - 0.032 14.9 0.0 0.078 13.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG81916.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG81917.1 - 0.00016 21.3 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Topo_Zn_Ribbon PF08272.11 GBG81917.1 - 0.016 14.9 0.1 0.039 13.6 0.1 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG81917.1 - 0.5 10.5 1.9 1 9.5 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG81918.1 - 2.2e-29 101.4 0.0 3.6e-15 55.8 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81918.1 - 8e-25 87.7 0.0 1.3e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81918.1 - 5.2e-20 71.7 0.0 1.4e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG81918.1 - 4.5e-12 45.7 0.0 9.7e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RexB PF15968.5 GBG81918.1 - 0.036 14.5 0.0 0.063 13.7 0.0 1.3 1 0 0 1 1 1 0 Membrane-anchored ion channel, Abi component RT_RNaseH_2 PF17919.1 GBG81919.1 - 5e-19 68.2 0.0 2.3e-18 66.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81919.1 - 4.9e-18 65.5 0.0 7.5e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81919.1 - 5.7e-09 36.2 0.0 1.4e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG81919.1 - 0.016 15.2 2.9 0.031 14.2 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle CpXC PF14353.6 GBG81919.1 - 0.19 11.8 0.1 0.57 10.2 0.0 1.7 2 0 0 2 2 2 0 CpXC protein UPF0242 PF06785.11 GBG81921.1 - 1.2 9.2 5.2 2.1 8.4 5.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF659 PF04937.15 GBG81922.1 - 5.2e-36 123.8 0.5 1.7e-35 122.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG81922.1 - 7.2e-32 109.4 0.0 1.5e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81922.1 - 6.9e-29 100.2 1.1 1.1e-28 99.5 0.2 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81922.1 - 1.2e-19 70.1 0.1 2.4e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Dimer_Tnp_hAT PF05699.14 GBG81922.1 - 6.3e-05 22.7 0.2 0.00019 21.1 0.2 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-H2C2 PF09337.10 GBG81922.1 - 0.00042 20.5 0.0 0.0019 18.4 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG81922.1 - 0.021 15.1 0.6 0.063 13.6 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein zf-C2HE PF16278.5 GBG81922.1 - 0.096 13.2 0.6 0.38 11.2 0.6 2.1 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger RVT_1 PF00078.27 GBG81923.1 - 5.6e-30 104.5 0.1 1.3e-29 103.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81923.1 - 2.3e-29 101.8 0.1 7e-29 100.2 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81923.1 - 4.5e-29 100.4 0.0 1.8e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG81923.1 - 0.082 12.5 0.2 0.082 12.5 0.2 3.0 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase ADP_ribosyl_GH PF03747.14 GBG81923.1 - 6.5 6.4 7.3 1 9.0 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylglycohydrolase RT_RNaseH_2 PF17919.1 GBG81924.1 - 1.4e-32 111.7 0.0 3.2e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81924.1 - 1.9e-19 69.9 0.0 4.7e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG81924.1 - 1.2e-18 67.0 0.1 2.6e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG81924.1 - 9.1e-17 61.4 0.1 3.5e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG81924.1 - 3e-12 46.5 0.2 6.1e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG81924.1 - 0.0026 17.9 0.0 0.0098 16.1 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG81926.1 - 4.4e-07 30.4 0.0 1.1e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81926.1 - 1.3e-06 28.8 0.0 4.4e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG81926.1 - 0.00054 19.7 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG81926.1 - 0.00055 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG81929.1 - 2.5e-23 82.0 0.0 4.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81929.1 - 1.1e-20 73.8 0.0 4.9e-20 71.8 0.0 2.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81929.1 - 1.4e-05 25.3 0.0 4.5e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG81929.1 - 0.0008 19.0 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BAT2_N PF07001.11 GBG81930.1 - 4.5e-05 24.0 0.1 4.5e-05 24.0 0.1 9.5 10 2 1 12 12 12 1 BAT2 N-terminus rve PF00665.26 GBG81931.1 - 4.7e-22 78.4 0.1 2.4e-13 50.3 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG81931.1 - 1.4e-16 60.4 0.1 4.1e-16 58.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Tudor-knot PF11717.8 GBG81931.1 - 0.00067 19.5 0.0 0.0024 17.7 0.0 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain WAK_assoc PF14380.6 GBG81931.1 - 0.03 15.0 0.9 0.03 15.0 0.9 2.7 2 0 0 2 2 2 0 Wall-associated receptor kinase C-terminal zf-CCHC_3 PF13917.6 GBG81931.1 - 0.096 12.7 3.2 0.23 11.5 3.2 1.6 1 0 0 1 1 1 0 Zinc knuckle HALZ PF02183.18 GBG81931.1 - 0.17 12.1 1.0 0.45 10.8 1.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GBG81931.1 - 3.3 7.9 4.7 1.7 8.8 1.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor RVT_1 PF00078.27 GBG81932.1 - 7.8e-25 87.7 0.0 2.2e-24 86.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81932.1 - 1.3e-20 73.3 0.0 7.2e-20 70.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81932.1 - 1.2e-19 70.5 0.0 3.3e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG81932.1 - 0.00044 20.5 0.0 0.0033 17.7 0.0 2.5 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG81932.1 - 0.0074 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF2730 PF10805.8 GBG81932.1 - 0.19 11.8 0.6 0.55 10.4 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) TRPM_tetra PF16519.5 GBG81932.1 - 0.79 9.9 5.6 6.6 6.9 0.2 3.3 3 0 0 3 3 3 0 Tetramerisation domain of TRPM DNA_pack_N PF02500.15 GBG81933.1 - 0.0073 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Probable DNA packing protein, N-terminus Spore_IV_A PF09547.10 GBG81933.1 - 0.0076 15.2 2.5 0.3 10.0 2.3 2.1 2 0 0 2 2 2 2 Stage IV sporulation protein A (spore_IV_A) ADIP PF11559.8 GBG81933.1 - 0.97 9.5 19.4 0.077 13.1 14.2 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 GBG81933.1 - 1.3 9.1 6.9 0.66 10.0 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RT_RNaseH_2 PF17919.1 GBG81934.1 - 4e-62 206.5 0.3 2.7e-32 110.8 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81934.1 - 1.4e-58 198.0 0.6 1.8e-31 109.4 0.0 3.5 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81934.1 - 4.2e-58 194.1 1.3 8.7e-28 96.7 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG81934.1 - 9.3e-06 26.2 0.0 0.039 14.6 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG81934.1 - 4.6e-05 23.9 0.0 0.0042 17.6 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease PaaX_C PF08223.11 GBG81934.1 - 0.0072 16.6 0.5 0.25 11.6 0.0 3.0 3 0 0 3 3 3 1 PaaX-like protein C-terminal domain DUF1758 PF05585.12 GBG81934.1 - 0.011 15.5 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative peptidase (DUF1758) zf-CCHC_3 PF13917.6 GBG81934.1 - 0.024 14.6 1.6 0.057 13.4 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle Phage_GPO PF05929.11 GBG81934.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF5095 PF17016.5 GBG81934.1 - 0.2 11.3 1.4 3.2 7.4 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5095) zf-CCHC PF00098.23 GBG81934.1 - 0.51 10.5 3.9 1.6 9.0 3.9 1.9 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG81936.1 - 4e-14 52.5 0.0 7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81936.1 - 3.2e-12 46.6 0.0 5.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81937.1 - 1.7e-17 63.3 0.0 3.7e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81937.1 - 2e-10 40.6 0.0 3.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81937.1 - 6.1e-08 32.9 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG81937.1 - 0.018 15.0 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF3432 PF11914.8 GBG81938.1 - 0.32 11.2 7.6 0.055 13.7 3.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) DUF2057 PF09829.9 GBG81939.1 - 0.014 15.6 3.0 0.63 10.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) CbiX PF01903.17 GBG81939.1 - 0.1 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 CbiX Ribosomal_60s PF00428.19 GBG81939.1 - 0.14 12.7 14.6 2.9 8.5 0.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF659 PF04937.15 GBG81940.1 - 7.4e-15 55.1 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG81940.1 - 1e-14 54.4 1.2 3e-14 52.9 0.1 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG81940.1 - 5.6e-14 52.4 0.1 3.3e-12 46.7 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG81940.1 - 3.2e-13 49.9 0.0 6.8e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG81940.1 - 0.00014 22.0 0.0 0.00034 20.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG81940.1 - 0.0052 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 GBG81940.1 - 0.073 12.9 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase-like rve_3 PF13683.6 GBG81940.1 - 0.13 12.0 0.0 0.43 10.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Histone PF00125.24 GBG81941.1 - 1.8e-20 73.7 0.1 1.8e-20 73.7 0.1 2.5 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CDC45 PF02724.14 GBG81942.1 - 4.5 5.4 5.7 5.4 5.2 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Dimer_Tnp_hAT PF05699.14 GBG81943.1 - 0.033 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.17 GBG81944.1 - 6.3e-05 23.2 0.7 0.00021 21.5 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein FUSC PF04632.12 GBG81944.1 - 7 5.0 7.7 12 4.3 7.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family RVT_1 PF00078.27 GBG81945.1 - 5e-28 98.1 0.3 1.5e-27 96.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG81945.1 - 7.1e-23 80.9 0.0 1.2e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81945.1 - 4.1e-20 71.7 0.0 9.4e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG81945.1 - 1.7e-09 37.5 0.0 3.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG81945.1 - 5.7e-08 33.3 0.0 1.1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81945.1 - 8.7e-07 29.4 0.0 1.6e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG81945.1 - 0.0016 18.2 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG81945.1 - 0.015 15.4 0.1 0.031 14.4 0.1 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain RVP PF00077.20 GBG81946.1 - 0.0034 17.7 0.1 0.058 13.7 0.1 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG81946.1 - 0.0064 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG81946.1 - 0.015 15.6 0.2 0.04 14.2 0.2 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG81946.1 - 0.018 15.6 0.1 0.046 14.3 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG81946.1 - 0.84 9.5 2.0 1.6 8.7 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG81947.1 - 3.3e-18 65.9 0.2 8e-18 64.7 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG81947.1 - 1.8e-15 57.1 0.0 5.6e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG81947.1 - 3.1e-12 46.4 0.1 7.6e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG81947.1 - 0.12 12.7 0.5 0.46 10.8 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG81948.1 - 8.2e-06 26.4 0.0 8e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG81948.1 - 3e-05 24.5 0.1 7.8e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG81948.1 - 0.003 17.5 4.0 0.0062 16.6 4.0 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG81948.1 - 0.086 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease TetR_C_34 PF17929.1 GBG81949.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CLZ PF16526.5 GBG81949.1 - 0.38 11.2 5.0 3.5 8.1 0.4 3.4 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2098 PF09871.9 GBG81950.1 - 3.8 7.9 6.7 11 6.4 6.7 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) EMP70 PF02990.16 GBG81952.1 - 6.9e-63 213.1 0.3 8.1e-63 212.9 0.3 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 zf-CCHC PF00098.23 GBG81953.1 - 4.9e-05 23.2 5.9 4.9e-05 23.2 5.9 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG81953.1 - 0.022 14.5 9.4 0.093 12.6 5.6 2.4 2 0 0 2 2 2 0 Zinc knuckle AP1AR PF15745.5 GBG81953.1 - 0.023 14.4 16.4 0.038 13.6 16.4 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein zf-CCHC_3 PF13917.6 GBG81953.1 - 0.025 14.5 4.3 0.092 12.7 4.3 1.9 1 0 0 1 1 1 0 Zinc knuckle DUF1682 PF07946.14 GBG81953.1 - 1 8.5 21.5 1.5 7.9 21.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CDC45 PF02724.14 GBG81953.1 - 1.5 7.0 9.7 1.7 6.8 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SmAKAP PF15127.6 GBG81953.1 - 1.9 9.7 13.2 0.81 10.9 10.1 2.0 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein Presenilin PF01080.17 GBG81953.1 - 2.1 7.0 7.5 2.4 6.8 7.5 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GBG81953.1 - 4.5 7.0 15.7 7.6 6.3 15.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVT_1 PF00078.27 GBG81954.1 - 3.6e-28 98.6 0.0 5.9e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ADK PF00406.22 GBG81958.1 - 1.6e-61 206.9 0.0 2.1e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GBG81958.1 - 6.3e-26 91.4 0.0 2.1e-25 89.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 GBG81958.1 - 4.5e-17 61.7 0.0 8.8e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 GBG81958.1 - 9.3e-07 29.1 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GBG81958.1 - 0.00054 20.5 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 GBG81958.1 - 0.0061 16.9 0.1 1 9.6 0.0 2.6 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 GBG81958.1 - 0.057 12.7 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DAP3 PF10236.9 GBG81958.1 - 0.094 11.9 0.2 0.62 9.2 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.15 GBG81958.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain RT_RNaseH PF17917.1 GBG81959.1 - 5.6e-24 84.4 3.6 1.1e-23 83.5 0.0 2.5 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG81959.1 - 3.6e-16 59.0 0.2 5.2e-15 55.3 0.0 2.6 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG81959.1 - 0.015 15.0 11.5 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase CODH_A_N PF18537.1 GBG81959.1 - 0.015 15.3 0.1 0.04 13.9 0.1 1.7 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Spc7 PF08317.11 GBG81959.1 - 0.019 13.9 12.3 0.03 13.2 12.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.14 GBG81959.1 - 0.032 14.6 15.8 0.084 13.2 15.8 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Utp8 PF10395.9 GBG81959.1 - 0.27 9.7 5.5 0.35 9.3 5.5 1.1 1 0 0 1 1 1 0 Utp8 family FlgN PF05130.12 GBG81959.1 - 0.57 10.7 17.7 0.99 9.9 17.7 1.4 1 0 0 1 1 1 0 FlgN protein DUF1664 PF07889.12 GBG81959.1 - 0.64 10.1 4.8 6 6.9 5.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 GBG81959.1 - 0.89 8.4 2.9 0.93 8.3 2.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Jnk-SapK_ap_N PF09744.9 GBG81959.1 - 1 9.6 18.7 2.1 8.6 18.7 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 GBG81959.1 - 1.5 6.3 22.3 2.1 5.8 22.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) P4Ha_N PF08336.11 GBG81959.1 - 1.6 8.7 11.3 4 7.5 3.0 2.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Tropomyosin PF00261.20 GBG81959.1 - 2 7.7 23.5 9.7 5.5 16.3 2.8 2 1 1 3 3 3 0 Tropomyosin Fib_alpha PF08702.10 GBG81959.1 - 3 8.0 9.8 15 5.8 0.2 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ApoO PF09769.9 GBG81959.1 - 3.8 7.5 5.9 1.6 8.7 0.4 2.3 2 0 0 2 2 2 0 Apolipoprotein O DUF4407 PF14362.6 GBG81959.1 - 6.5 6.0 17.4 13 5.1 17.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF659 PF04937.15 GBG81960.1 - 4.7e-31 107.7 0.1 6.8e-31 107.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Filament PF00038.21 GBG81961.1 - 2.8 7.5 39.7 0.026 14.1 20.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF948 PF06103.11 GBG81961.1 - 6.2 7.2 9.8 3.2e+03 -1.5 9.8 3.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4618 PF15397.6 GBG81962.1 - 0.00078 18.9 14.5 0.00097 18.6 14.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF4472 PF14739.6 GBG81962.1 - 0.038 14.7 3.2 0.038 14.7 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Leu_zip PF15294.6 GBG81962.1 - 0.16 11.4 18.3 0.18 11.3 18.3 1.1 1 0 0 1 1 1 0 Leucine zipper Rootletin PF15035.6 GBG81962.1 - 0.18 11.8 22.5 0.24 11.4 16.9 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Golgin_A5 PF09787.9 GBG81962.1 - 0.4 10.1 21.6 0.44 10.0 21.6 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1664 PF07889.12 GBG81962.1 - 0.93 9.5 9.8 5.7 7.0 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 GBG81962.1 - 1.7 8.2 18.1 5.1 6.7 18.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4890 PF16231.5 GBG81962.1 - 1.8 9.1 14.8 0.24 11.9 8.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4890) KxDL PF10241.9 GBG81962.1 - 2.2 8.6 17.1 1 9.6 8.1 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein AAA_13 PF13166.6 GBG81962.1 - 2.6 6.6 18.1 3.1 6.3 18.1 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 GBG81962.1 - 3.3 6.5 23.5 3.6 6.4 23.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 GBG81962.1 - 4.3 6.8 14.5 5 6.6 14.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit betaPIX_CC PF16523.5 GBG81962.1 - 5.8 6.8 17.4 5.2 7.0 6.0 3.2 1 1 1 2 2 2 0 betaPIX coiled coil 5-nucleotidase PF06189.12 GBG81963.1 - 0.033 13.1 2.4 0.04 12.9 2.4 1.3 1 1 0 1 1 1 0 5'-nucleotidase LprI PF07007.12 GBG81963.1 - 0.16 12.6 11.0 0.28 11.9 10.9 1.4 1 1 0 1 1 1 0 Lysozyme inhibitor LprI Gp23 PF07068.11 GBG81963.1 - 0.24 10.1 1.5 0.27 10.0 1.5 1.0 1 0 0 1 1 1 0 Major capsid protein Gp23 DUF445 PF04286.12 GBG81963.1 - 1.4 8.7 9.0 1.4 8.6 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) betaPIX_CC PF16523.5 GBG81963.1 - 1.9 8.4 13.9 1.7 8.5 2.9 2.8 1 1 1 2 2 2 0 betaPIX coiled coil Exonuc_VII_L PF02601.15 GBG81963.1 - 7.2 6.1 11.4 7.5 6.0 11.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4618 PF15397.6 GBG81964.1 - 0.00066 19.2 10.6 0.00082 18.9 10.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Spc7 PF08317.11 GBG81964.1 - 0.14 11.0 17.2 0.18 10.7 17.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.19 GBG81964.1 - 0.15 11.8 17.6 0.19 11.5 17.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4890 PF16231.5 GBG81964.1 - 0.18 12.3 9.0 0.24 11.9 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) Macoilin PF09726.9 GBG81964.1 - 0.63 8.5 13.1 0.69 8.4 13.1 1.1 1 0 0 1 1 1 0 Macoilin family Jnk-SapK_ap_N PF09744.9 GBG81964.1 - 0.86 9.8 18.2 1 9.5 18.2 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 KxDL PF10241.9 GBG81964.1 - 1.1 9.6 14.4 0.97 9.8 8.6 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF4795 PF16043.5 GBG81964.1 - 1.3 8.6 14.1 6.2 6.4 14.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1664 PF07889.12 GBG81964.1 - 1.3 9.0 5.9 4.4 7.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 GBG81964.1 - 1.4 8.3 16.0 1.7 8.0 16.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 GBG81964.1 - 2.3 7.4 8.9 2.7 7.2 8.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 GBG81964.1 - 3 7.9 20.5 1.1e+02 2.9 20.5 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 GBG81964.1 - 3.4 6.6 10.9 3.9 6.5 10.9 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 GBG81964.1 - 5.6 7.4 14.4 11 6.4 14.5 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 GBG81964.1 - 7.6 6.7 21.3 2.7 8.2 4.4 3.8 2 2 2 4 4 4 0 Basic region leucine zipper SseC PF04888.12 GBG81964.1 - 7.8 6.0 12.2 1.8 8.1 3.4 2.0 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family YojJ PF10372.9 GBG81964.1 - 10 6.3 9.1 11 6.2 5.0 2.2 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF659 PF04937.15 GBG81965.1 - 4.8e-29 101.2 0.0 6.8e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG81965.1 - 7.4e-09 35.3 1.1 0.0014 18.4 0.2 2.4 2 0 0 2 2 2 2 hAT family C-terminal dimerisation region rve PF00665.26 GBG81966.1 - 9.7e-11 41.9 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG81966.1 - 0.028 14.5 1.4 0.082 13.0 1.4 1.9 1 0 0 1 1 1 0 Zinc knuckle Ax_dynein_light PF10211.9 GBG81967.1 - 0.00028 20.9 4.1 0.00054 20.0 4.1 1.4 1 0 0 1 1 1 1 Axonemal dynein light chain Spc7 PF08317.11 GBG81967.1 - 0.043 12.7 3.7 0.078 11.8 3.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Met_10 PF02475.16 GBG81968.1 - 1.6e-58 197.7 0.0 2.4e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 GBG81968.1 - 0.00015 21.1 0.0 0.00022 20.5 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 GBG81968.1 - 0.00032 20.2 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GBG81968.1 - 0.0022 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 GBG81968.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 GBG81968.1 - 0.024 15.3 0.0 0.063 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 GBG81968.1 - 0.042 13.5 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MethyltransfD12 PF02086.15 GBG81968.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase zf-CCHC PF00098.23 GBG81969.1 - 3.7e-07 29.9 4.2 3.7e-07 29.9 4.2 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG81969.1 - 0.21 11.3 0.7 0.43 10.4 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle HTH_57 PF18679.1 GBG81969.1 - 0.67 10.3 2.4 0.85 10.0 0.5 2.1 2 0 0 2 2 2 0 ThcOx helix turn helix domain WD40_alt PF14077.6 GBG81969.1 - 2.2 8.2 6.3 38 4.2 0.0 4.1 4 0 0 4 4 4 0 Alternative WD40 repeat motif zf-CCHC PF00098.23 GBG81970.1 - 0.0072 16.4 0.6 0.018 15.1 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle RRM_1 PF00076.22 GBG81971.1 - 1.4e-17 63.3 0.0 1.9e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG81971.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4603 PF15376.6 GBG81971.1 - 3 5.1 5.5 3.6 4.9 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) RRM_1 PF00076.22 GBG81972.1 - 1.4e-17 63.3 0.0 2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG81972.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4603 PF15376.6 GBG81972.1 - 3 5.1 5.5 3.7 4.8 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) RRM_1 PF00076.22 GBG81973.1 - 1.4e-17 63.3 0.0 2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG81973.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4603 PF15376.6 GBG81973.1 - 6.3 4.0 5.7 7.8 3.8 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) KxDL PF10241.9 GBG81974.1 - 0.12 12.7 1.1 4.2 7.7 0.1 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein Ribosomal_S13 PF00416.22 GBG81975.1 - 2.4e-55 186.4 1.4 2.8e-55 186.2 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 GBG81975.1 - 0.017 15.6 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) HHH_6 PF14579.6 GBG81975.1 - 0.022 15.0 0.1 0.064 13.5 0.1 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix motif FbpA PF05833.11 GBG81975.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.9 GBG81975.1 - 0.19 12.2 2.0 0.22 12.0 1.1 1.6 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Ribosomal_S13 PF00416.22 GBG81977.1 - 2.4e-55 186.4 1.4 2.8e-55 186.2 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 GBG81977.1 - 0.017 15.6 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) HHH_6 PF14579.6 GBG81977.1 - 0.022 15.0 0.1 0.064 13.5 0.1 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix motif FbpA PF05833.11 GBG81977.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.9 GBG81977.1 - 0.19 12.2 2.0 0.22 12.0 1.1 1.6 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 WD40 PF00400.32 GBG81978.1 - 0.39 11.7 2.0 41 5.3 0.1 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Myb_DNA-bind_4 PF13837.6 GBG81981.1 - 3.2e-07 30.6 3.5 6.2e-07 29.7 3.2 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG81981.1 - 0.055 13.7 1.5 0.11 12.8 1.5 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG81981.1 - 0.11 12.8 1.5 0.24 11.7 1.5 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG81981.1 - 0.17 12.0 2.0 0.35 11.0 2.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF647 PF04884.14 GBG81982.1 - 8.5e-67 225.3 0.7 1.3e-66 224.7 0.1 1.6 2 0 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis Mit_KHE1 PF10173.9 GBG81984.1 - 2.8e-34 118.9 0.2 5.7e-34 117.9 0.2 1.5 1 1 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Lyase_1 PF00206.20 GBG81985.1 - 6.1e-18 65.3 0.1 1.2e-12 47.9 0.0 2.0 2 0 0 2 2 2 2 Lyase RT_RNaseH_2 PF17919.1 GBG81987.1 - 1.4e-23 82.8 0.0 3e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG81987.1 - 6.6e-21 74.6 0.0 1.4e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG81987.1 - 1.2e-09 38.1 0.1 2.1e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG81987.1 - 0.023 14.7 1.6 0.057 13.5 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Ins145_P3_rec PF08709.11 GBG81989.1 - 0.03 13.5 0.0 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Dor1 PF04124.12 GBG81990.1 - 9.8e-127 422.3 2.2 1.2e-126 421.9 2.2 1.1 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 GBG81990.1 - 2.1e-09 37.3 1.2 8.2e-09 35.4 0.2 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Vps54_N PF10475.9 GBG81990.1 - 5e-06 26.0 4.0 5e-06 26.0 4.0 1.5 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Exo84_C PF16528.5 GBG81990.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.6 1 1 0 1 1 1 1 Exocyst component 84 C-terminal PLU-1 PF08429.11 GBG81990.1 - 0.0044 16.2 1.0 0.0065 15.7 1.0 1.2 1 0 0 1 1 1 1 PLU-1-like protein Sec5 PF15469.6 GBG81990.1 - 0.0045 16.8 0.1 0.0085 15.9 0.1 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 Zw10 PF06248.13 GBG81990.1 - 0.051 12.1 1.8 0.083 11.4 1.8 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 COG2 PF06148.11 GBG81990.1 - 0.11 12.6 3.4 0.055 13.6 0.7 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 GBG81990.1 - 0.15 10.9 4.5 0.08 11.8 0.8 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein RPAP3_C PF13877.6 GBG81990.1 - 0.18 12.4 0.4 1.8 9.1 0.1 2.6 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 Prefoldin PF02996.17 GBG81990.1 - 0.37 10.7 2.6 3.3 7.6 0.1 2.7 2 1 1 3 3 3 0 Prefoldin subunit GlutR_dimer PF00745.20 GBG81990.1 - 0.56 10.7 2.7 1.7 9.2 0.0 2.8 3 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain TMF_TATA_bd PF12325.8 GBG81990.1 - 2.6 8.3 6.6 0.97 9.7 1.5 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding COG5 PF10392.9 GBG81990.1 - 4.3 7.5 5.6 6.1 7.0 0.2 2.9 2 1 1 3 3 3 0 Golgi transport complex subunit 5 FliT PF05400.13 GBG81990.1 - 6.1 7.7 7.6 2.1 9.2 0.2 3.5 3 1 1 4 4 4 0 Flagellar protein FliT KH_7 PF17214.3 GBG81992.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 KH domain GDP_Man_Dehyd PF16363.5 GBG81993.1 - 8.4e-66 222.6 0.0 1.2e-65 222.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG81993.1 - 5.6e-52 176.6 0.0 8.9e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GBG81993.1 - 1.5e-15 57.1 0.0 5.5e-15 55.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GBG81993.1 - 1.5e-14 53.7 0.0 3.7e-14 52.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GBG81993.1 - 6.2e-10 38.6 0.0 1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GBG81993.1 - 1.4e-06 27.9 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GBG81993.1 - 3.6e-06 27.0 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 GBG81993.1 - 2e-05 23.9 0.0 0.00038 19.7 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 GBG81993.1 - 0.00081 19.3 0.0 0.0029 17.5 0.0 1.9 2 1 0 2 2 2 1 NAD(P)H-binding 3HCDH_N PF02737.18 GBG81993.1 - 0.021 14.7 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BSP_II PF05432.11 GBG81994.1 - 0.046 13.4 25.9 0.11 12.2 25.9 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Amidohydro_1 PF01979.20 GBG81995.1 - 3.3e-35 122.0 0.0 4.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GBG81995.1 - 8.3e-12 45.3 0.2 1.9e-05 24.4 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family TatD_DNase PF01026.21 GBG81995.1 - 0.018 14.5 0.1 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 TatD related DNase Aminotran_5 PF00266.19 GBG81996.1 - 3.3e-56 190.8 0.0 4e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Dynein_C PF18199.1 GBG81998.1 - 1.5e-109 366.0 0.0 2.7e-109 365.1 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 GBG81998.1 - 6.6e-85 283.7 0.0 2.9e-84 281.6 0.1 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 GBG81998.1 - 2.8e-61 206.1 0.0 4.7e-61 205.4 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GBG81998.1 - 4.3e-46 155.9 0.0 1.1e-44 151.3 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 GBG81998.1 - 2.5e-37 128.7 17.7 5.4e-31 107.9 4.4 3.1 3 0 0 3 3 3 2 Microtubule-binding stalk of dynein motor RVT_1 PF00078.27 GBG81998.1 - 6.2e-09 35.7 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG81998.1 - 2.7e-08 33.7 0.0 8.2e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG81998.1 - 2e-07 31.4 0.0 5.7e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG81998.1 - 4.7e-06 27.1 0.0 1.2e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG81998.1 - 5.2e-06 26.7 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AAA_8 PF12780.7 GBG81998.1 - 1.2e-05 24.8 1.6 1.9e-05 24.1 1.6 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Asp_protease PF09668.10 GBG81998.1 - 0.0042 16.9 0.2 0.0097 15.7 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease CCDC144C PF14915.6 GBG81998.1 - 0.053 12.6 14.1 1.1 8.3 1.0 2.6 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region RVP PF00077.20 GBG81998.1 - 0.087 13.1 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease AAA_8 PF12780.7 GBG81999.1 - 5.8e-59 199.5 0.1 8.2e-59 199.0 0.1 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_lid_1 PF17857.1 GBG81999.1 - 2.2e-18 66.3 0.1 5e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 GBG81999.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 GBG82002.1 - 1.7e-159 530.1 0.0 2.3e-156 519.8 0.0 2.3 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 GBG82002.1 - 2.9e-62 209.4 0.3 1.8e-59 200.3 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 GBG82002.1 - 1.2e-33 116.0 0.0 3.4e-33 114.5 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain RVT_1 PF00078.27 GBG82002.1 - 7e-29 100.9 0.0 9.1e-28 97.3 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_5 PF07728.14 GBG82002.1 - 3.4e-15 56.2 0.0 0.00092 19.2 0.0 4.5 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) Asp_protease_2 PF13650.6 GBG82002.1 - 1.2e-11 45.0 0.0 1.2e-07 32.3 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG82002.1 - 2.5e-10 40.8 0.0 1.2e-06 29.0 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease AAA PF00004.29 GBG82002.1 - 1.1e-07 32.3 0.0 0.0044 17.5 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RVP_2 PF08284.11 GBG82002.1 - 1.1e-06 28.5 0.0 5.2e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82002.1 - 1.5e-05 24.8 0.0 0.00086 19.1 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RNA_helicase PF00910.22 GBG82002.1 - 0.0015 18.9 0.6 5.3 7.5 0.0 3.7 4 0 0 4 4 3 1 RNA helicase AAA_18 PF13238.6 GBG82002.1 - 0.0025 18.4 0.0 0.062 13.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GBG82002.1 - 0.0026 17.8 0.0 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GBG82002.1 - 0.003 17.8 2.4 0.24 11.6 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 GBG82002.1 - 0.0096 16.3 4.1 2.3 8.6 0.0 4.0 3 1 0 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 GBG82002.1 - 0.016 15.1 0.1 3.2 7.6 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain RVP PF00077.20 GBG82002.1 - 0.022 15.1 0.1 12 6.3 0.0 2.7 2 0 0 2 2 2 0 Retroviral aspartyl protease T2SSE PF00437.20 GBG82002.1 - 0.037 13.1 0.6 0.077 12.1 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 GBG82002.1 - 0.056 13.7 0.2 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 GBG82002.1 - 0.11 12.2 0.2 18 5.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 GBG82002.1 - 0.12 11.7 0.4 15 4.9 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GBG82002.1 - 0.16 12.2 6.7 15 5.7 0.0 4.4 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 GBG82002.1 - 0.2 11.6 4.8 6.3 6.8 0.1 3.5 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DDE_Tnp_4 PF13359.6 GBG82003.1 - 4.6e-33 114.1 0.0 5e-31 107.5 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82003.1 - 1e-14 54.7 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein RT_RNaseH_2 PF17919.1 GBG82004.1 - 8.8e-29 99.5 0.0 1.9e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82004.1 - 4.1e-26 91.3 0.0 8.6e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82004.1 - 1.1e-09 38.1 0.1 3.3e-09 36.6 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG82004.1 - 2.8e-08 34.0 2.0 6.7e-08 32.8 0.7 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG82004.1 - 0.031 14.3 2.7 0.071 13.2 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle APG12 PF04110.13 GBG82005.1 - 1.4e-24 86.3 0.0 2.2e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 RT_RNaseH_2 PF17919.1 GBG82006.1 - 2.1e-31 107.9 0.0 1.2e-30 105.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82006.1 - 7.2e-31 106.6 0.1 5.4e-30 103.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82006.1 - 2.6e-19 69.6 0.3 5.7e-13 48.9 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82006.1 - 3.6e-16 59.0 1.4 7.8e-16 57.9 1.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82006.1 - 7.3e-15 55.2 0.0 2.2e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG82006.1 - 0.00011 21.9 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82006.1 - 0.0043 17.7 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG82006.1 - 0.074 13.3 0.2 0.21 11.9 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG82006.1 - 0.15 12.6 0.0 0.4 11.3 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG82006.1 - 0.18 11.5 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DRY_EERY PF09750.9 GBG82006.1 - 4.9 7.4 7.8 23 5.2 0.0 2.8 2 0 0 2 2 2 0 Alternative splicing regulator SDA1 PF05285.12 GBG82008.1 - 0.27 10.6 61.5 0.47 9.8 61.5 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG82008.1 - 2.2 7.5 57.1 2.8 7.2 57.1 1.1 1 0 0 1 1 1 0 BUD22 VWA PF00092.28 GBG82009.1 - 4.8e-06 26.9 1.1 9e-06 26.1 1.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 GBG82009.1 - 0.0055 16.5 1.6 1.9 8.2 0.9 2.6 2 1 0 2 2 2 2 Cache domain VWA_N PF08399.11 GBG82009.1 - 0.19 12.2 0.0 0.43 11.1 0.0 1.5 1 0 0 1 1 1 0 VWA N-terminal TMEM213 PF15192.6 GBG82010.1 - 0.19 11.7 0.0 0.5 10.4 0.0 1.7 1 0 0 1 1 1 0 TMEM213 family RBM39linker PF15519.6 GBG82010.1 - 0.2 12.8 2.7 0.77 10.9 0.4 2.4 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein PBP1_TM PF14812.6 GBG82012.1 - 6.2 7.3 43.0 0.28 11.6 14.5 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 GBG82012.1 - 6.5 6.4 25.5 0.48 10.1 1.2 3.1 3 0 0 3 3 3 0 FAM176 family 5-FTHF_cyc-lig PF01812.20 GBG82014.1 - 4.6e-31 108.1 0.1 8e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family CDC45 PF02724.14 GBG82015.1 - 0.29 9.4 6.8 0.37 9.0 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TP53IP5 PF15331.6 GBG82016.1 - 0.52 10.4 10.8 0.59 10.3 10.8 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PA26 PF04636.13 GBG82016.1 - 6.2 5.6 9.7 6.7 5.5 9.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 GBG82016.1 - 6.7 4.7 8.8 7.4 4.6 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.6 GBG82016.1 - 8.9 5.6 10.2 11 5.3 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fer4_9 PF13187.6 GBG82018.1 - 0.006 16.7 2.0 3.1 8.0 0.1 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 GBG82018.1 - 2.4 8.4 13.0 0.99 9.6 10.2 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Actin PF00022.19 GBG82019.1 - 2e-149 497.7 0.0 6.4e-149 496.0 0.0 1.6 1 1 0 1 1 1 1 Actin zf-UBR PF02207.20 GBG82020.1 - 9.1e-19 67.4 9.8 9.1e-19 67.4 9.8 3.0 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Radial_spoke PF04712.12 GBG82020.1 - 1.1 8.1 7.5 2.3 7.1 7.5 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein Tmemb_9 PF05434.11 GBG82020.1 - 5 7.0 9.3 0.15 12.0 1.4 2.4 3 0 0 3 3 3 0 TMEM9 DUF659 PF04937.15 GBG82021.1 - 4.9e-07 29.7 0.0 9.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG82021.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG82022.1 - 1.2e-26 93.6 0.1 2.3e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82022.1 - 8.3e-21 73.9 0.0 1.9e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82022.1 - 2.3e-20 72.9 0.0 6.7e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG82022.1 - 2.4e-06 27.4 0.0 5.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82022.1 - 4e-06 27.4 0.0 1.3e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82022.1 - 4.2e-06 27.2 0.0 1.1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82022.1 - 0.0005 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG82022.1 - 0.0072 16.6 0.3 0.032 14.5 0.3 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.24 GBG82022.1 - 0.027 14.4 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain APG17 PF04108.12 GBG82022.1 - 0.12 11.5 0.0 3.6 6.6 0.0 2.5 2 1 1 3 3 3 0 Autophagy protein Apg17 Pkinase_Tyr PF07714.17 GBG82024.1 - 9.1e-37 126.7 0.0 1.8e-36 125.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82024.1 - 4e-34 118.2 0.0 2.8e-33 115.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG82024.1 - 2.3e-07 31.0 0.0 5.3e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG82024.1 - 0.00028 19.8 0.0 0.00066 18.6 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase EphA2_TM PF14575.6 GBG82024.1 - 0.019 15.8 0.0 1.4 9.9 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 GBG82024.1 - 0.02 14.8 1.2 0.28 11.0 0.3 2.4 1 1 1 2 2 2 0 Transmembrane protein 51 DUF4381 PF14316.6 GBG82024.1 - 0.032 14.5 0.1 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Herpes_gE PF02480.16 GBG82024.1 - 0.071 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF659 PF04937.15 GBG82025.1 - 4.3e-28 98.1 0.0 7.4e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) NR_Repeat PF14046.6 GBG82025.1 - 0.00057 20.0 0.3 0.0054 16.8 0.2 2.7 2 0 0 2 2 2 1 Nuclear receptor repeat Dimer_Tnp_hAT PF05699.14 GBG82025.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Suf PF05843.14 GBG82026.1 - 0.11 12.5 0.4 0.15 12.0 0.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MIT_C PF16565.5 GBG82026.1 - 0.15 12.1 0.2 0.73 9.8 0.1 2.0 2 0 0 2 2 2 0 Phospholipase D-like domain at C-terminus of MIT UPF0561 PF10573.9 GBG82026.1 - 0.31 11.2 3.2 0.52 10.5 1.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 BSP_II PF05432.11 GBG82026.1 - 1.9 8.1 11.0 3.1 7.4 11.0 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RT_RNaseH_2 PF17919.1 GBG82027.1 - 6e-24 84.0 0.0 1.1e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82027.1 - 1.7e-21 76.5 0.0 2.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG82027.1 - 0.015 15.8 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG82027.1 - 0.018 15.4 0.0 0.053 13.8 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82027.1 - 0.055 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG82028.1 - 5.8e-28 97.5 0.0 1.1e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82028.1 - 1.7e-11 44.1 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82028.1 - 0.0013 18.4 1.5 0.85 9.2 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain CitMHS PF03600.16 GBG82030.1 - 0.0068 15.6 0.2 0.0093 15.2 0.2 1.3 1 0 0 1 1 1 1 Citrate transporter Myb_DNA-bind_4 PF13837.6 GBG82031.1 - 2e-07 31.3 0.8 2e-07 31.3 0.8 2.3 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG82032.1 - 8.5e-27 93.8 0.0 1.6e-25 89.7 0.0 2.6 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82032.1 - 1.7e-12 47.4 0.0 2.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Tetraspanin PF00335.20 GBG82033.1 - 0.00011 22.1 4.3 0.00016 21.5 4.3 1.3 1 1 0 1 1 1 1 Tetraspanin family Claudin_3 PF06653.11 GBG82033.1 - 0.012 15.5 1.0 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like zf-MYND PF01753.18 GBG82034.1 - 1.1e-08 35.0 18.4 2.2e-08 34.1 18.4 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 GBG82034.1 - 1.8 8.9 11.8 3.8 7.9 11.8 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding RT_RNaseH PF17917.1 GBG82035.1 - 5.5e-20 71.6 0.0 1.3e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82035.1 - 2e-18 66.3 0.0 4.8e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG82035.1 - 1.7e-06 28.5 0.0 4.6e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG82035.1 - 1e-05 25.1 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG82035.1 - 1.8e-05 25.2 0.1 6e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG82035.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Pep_deformylase PF01327.21 GBG82035.1 - 0.11 12.0 1.1 0.27 10.8 1.1 1.6 1 0 0 1 1 1 0 Polypeptide deformylase Cdc6_C PF09079.11 GBG82036.1 - 5.2e-16 58.4 0.9 1.3e-15 57.1 0.1 2.2 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 GBG82036.1 - 5.5e-15 55.9 0.0 1.3e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain MBD PF01429.19 GBG82036.1 - 4.8e-11 42.2 0.1 1.5e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Methyl-CpG binding domain AAA PF00004.29 GBG82036.1 - 5.9e-08 33.2 0.0 1.7e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG82036.1 - 9e-08 32.7 0.3 6.9e-07 29.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GBG82036.1 - 7.4e-06 26.0 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_lid_10 PF17872.1 GBG82036.1 - 0.00037 20.5 1.0 0.0017 18.4 0.1 2.3 2 0 0 2 2 2 1 AAA lid domain AAA_19 PF13245.6 GBG82036.1 - 0.00048 20.5 0.1 0.0011 19.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG82036.1 - 0.0033 17.2 0.0 0.009 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 GBG82036.1 - 0.0043 16.5 0.6 0.025 14.0 0.6 2.1 1 1 0 1 1 1 1 Bacterial TniB protein AT_hook PF02178.19 GBG82036.1 - 0.013 15.3 13.6 0.83 9.7 2.1 3.1 2 0 0 2 2 2 0 AT hook motif PIF1 PF05970.14 GBG82036.1 - 0.019 14.2 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Sigma54_activat PF00158.26 GBG82036.1 - 0.023 14.4 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 GBG82036.1 - 0.032 14.5 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GBG82036.1 - 0.048 14.2 0.4 0.23 12.0 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 GBG82036.1 - 0.098 12.2 0.0 0.72 9.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region RT_RNaseH PF17917.1 GBG82037.1 - 4.6e-22 78.3 0.0 8.3e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82037.1 - 7.1e-20 70.9 0.0 1.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82037.1 - 1.1e-17 63.9 1.1 2.2e-17 62.9 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82037.1 - 0.0025 18.0 0.0 0.0079 16.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG82037.1 - 0.069 13.4 0.6 0.12 12.6 0.6 1.4 1 0 0 1 1 1 0 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG82038.1 - 3.3e-15 55.9 1.1 9.7e-15 54.4 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG82038.1 - 1.6e-08 35.0 0.2 7.4e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82038.1 - 6.7e-05 23.5 0.2 0.00039 21.0 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG82038.1 - 0.0043 17.3 0.0 0.024 14.9 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG82038.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG82038.1 - 0.13 12.1 0.5 0.28 11.0 0.5 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG82039.1 - 0.1 12.7 0.4 0.28 11.3 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG82040.1 - 3.4e-05 24.3 0.0 6.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82040.1 - 0.0008 20.0 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82040.1 - 0.061 13.1 0.8 0.098 12.5 0.8 1.2 1 0 0 1 1 1 0 Aspartyl protease Glutaredoxin PF00462.24 GBG82040.1 - 0.12 12.6 0.4 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin FAM176 PF14851.6 GBG82040.1 - 1 9.0 5.3 0.64 9.7 3.1 1.7 2 0 0 2 2 2 0 FAM176 family RPN2_C PF18004.1 GBG82040.1 - 1.5 8.7 7.9 2.6 8.0 7.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nucleo_P87 PF07267.11 GBG82040.1 - 1.9 7.2 6.1 2.7 6.7 6.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1853 PF08907.11 GBG82045.1 - 2.5e-13 50.4 9.3 6.1e-05 22.9 1.4 5.2 5 1 0 5 5 5 3 Domain of unknown function (DUF1853) SRP-alpha_N PF04086.13 GBG82046.1 - 1.6 8.6 13.0 1.9 8.3 13.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TFIIA PF03153.13 GBG82046.1 - 5.7 6.8 16.7 6.6 6.6 16.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4551 PF15087.6 GBG82046.1 - 8.4 5.1 9.0 9.7 4.9 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) KBP_C PF12309.8 GBG82048.1 - 3.8e-56 191.1 2.8 4.9e-42 144.8 0.1 4.0 3 1 0 3 3 3 2 KIF-1 binding protein C terminal Peptidase_S64 PF08192.11 GBG82048.1 - 0.014 14.0 0.1 0.014 14.0 0.1 1.8 2 0 0 2 2 2 0 Peptidase family S64 TPR_7 PF13176.6 GBG82048.1 - 0.019 14.9 2.5 0.75 10.0 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG82048.1 - 0.08 12.8 0.2 0.08 12.8 0.2 2.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Zip PF02535.22 GBG82048.1 - 0.14 11.3 0.3 0.26 10.4 0.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.12 GBG82048.1 - 0.44 9.5 8.5 0.87 8.5 8.5 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARP1 PF12569.8 GBG82048.1 - 0.86 8.4 13.8 8 5.2 11.7 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 GBG82048.1 - 1.3 9.3 8.3 28 5.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3304 PF11745.8 GBG82048.1 - 1.7 9.1 6.5 8.4 6.8 6.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) TPR_1 PF00515.28 GBG82048.1 - 2.5 8.1 12.8 0.063 13.1 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4746 PF15928.5 GBG82048.1 - 9.2 5.6 14.6 22 4.3 14.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 GBG82049.1 - 0.52 10.5 17.3 0.67 10.2 15.3 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.12 GBG82049.1 - 0.63 9.4 9.6 0.25 10.7 6.9 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 GBG82049.1 - 1.6 6.9 13.0 1.9 6.6 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 GBG82049.1 - 6.5 5.9 7.9 11 5.1 7.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Aminotran_1_2 PF00155.21 GBG82050.1 - 1.1e-87 294.6 0.0 1.3e-87 294.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Transcrip_reg PF01709.20 GBG82051.1 - 5.9e-62 209.2 0.1 6.9e-62 209.0 0.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator BAG PF02179.16 GBG82051.1 - 0.0069 16.8 0.1 0.015 15.7 0.1 1.6 1 0 0 1 1 1 1 BAG domain DASH_Dam1 PF08653.10 GBG82053.1 - 0.042 13.6 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 V_ATPase_I PF01496.19 GBG82054.1 - 5.2 4.9 7.8 5.9 4.7 7.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ldh_1_N PF00056.23 GBG82055.1 - 7e-38 129.9 0.0 1.1e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 GBG82055.1 - 1.6e-32 112.7 0.0 1e-31 110.2 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 GBG82055.1 - 9.9e-06 24.8 0.0 2e-05 23.8 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 GBG82055.1 - 0.004 17.6 0.0 0.0086 16.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain zf-CCHC_2 PF13696.6 GBG82056.1 - 3.2 7.7 9.9 0.057 13.3 3.1 1.6 2 0 0 2 2 2 0 Zinc knuckle CdiI_2 PF18593.1 GBG82056.1 - 8.6 7.1 12.2 7.8 7.2 0.2 4.3 3 1 1 4 4 4 0 CdiI immunity protein Plavaka PF18759.1 GBG82057.1 - 1.8e-20 73.4 0.2 3.1e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Plavaka transposase Peptidase_C48 PF02902.19 GBG82057.1 - 2.2e-06 27.7 1.2 3.9e-06 26.9 1.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF659 PF04937.15 GBG82058.1 - 2.4e-12 47.0 0.0 5.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG82058.1 - 3.4e-08 33.7 0.4 2e-07 31.2 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain TPH PF13868.6 GBG82059.1 - 2.7e-70 236.6 155.7 2.7e-70 236.6 155.7 4.4 4 0 0 4 4 4 1 Trichohyalin-plectin-homology domain Endonuclease_5 PF04493.14 GBG82060.1 - 4.9e-64 215.7 0.0 8e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 GBG82060.1 - 0.038 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 TssN PF17555.2 GBG82060.1 - 0.4 10.0 3.9 0.77 9.1 3.9 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN SelK_SelG PF10961.8 GBG82060.1 - 0.45 11.2 7.3 18 6.0 0.0 3.4 3 0 0 3 3 3 0 Selenoprotein SelK_SelG RVT_1 PF00078.27 GBG82062.1 - 7e-22 78.0 0.0 1.2e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pectinesterase PF01095.19 GBG82063.1 - 1.7e-69 233.9 0.0 2.2e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Pectinesterase ELFV_dehydrog PF00208.21 GBG82065.1 - 2.2e-51 174.9 0.0 5.9e-51 173.5 0.0 1.7 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 GBG82065.1 - 2.4e-34 118.0 1.5 6.8e-31 106.8 0.0 2.5 1 1 1 2 2 2 2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 GBG82065.1 - 0.094 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 GBG82065.1 - 0.1 12.6 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain tRNA_deacylase PF04414.12 GBG82066.1 - 5.4e-56 189.4 0.0 8.7e-56 188.7 0.0 1.3 1 1 0 1 1 1 1 D-aminoacyl-tRNA deacylase DUF4334 PF14232.6 GBG82067.1 - 1.3e-27 95.5 0.2 2.7e-27 94.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 GBG82067.1 - 1.8e-21 76.0 0.1 4.8e-21 74.6 0.1 1.7 2 0 0 2 2 1 1 GXWXG protein Asp_protease_2 PF13650.6 GBG82067.1 - 7.7e-07 29.7 0.0 2.8e-06 27.9 0.0 2.0 2 0 0 2 2 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82067.1 - 8.5e-07 28.8 0.0 2.3e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG82067.1 - 1.1e-06 29.0 0.0 4.8e-06 27.0 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82067.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease CDC45 PF02724.14 GBG82067.1 - 0.0027 16.1 20.4 0.0035 15.7 20.4 1.1 1 0 0 1 1 1 1 CDC45-like protein DDHD PF02862.17 GBG82067.1 - 0.0067 16.6 9.1 0.0093 16.2 9.1 1.2 1 0 0 1 1 1 1 DDHD domain RPN2_C PF18004.1 GBG82067.1 - 0.0086 16.0 30.2 0.016 15.1 30.2 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain SET PF00856.28 GBG82067.1 - 0.011 16.2 0.8 0.016 15.6 0.8 1.4 1 0 0 1 1 1 0 SET domain SWI-SNF_Ssr4 PF08549.10 GBG82067.1 - 0.012 14.4 7.8 0.015 14.0 7.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Rtf2 PF04641.12 GBG82067.1 - 0.032 13.6 30.7 0.055 12.8 30.7 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger RPOL_N PF14700.6 GBG82067.1 - 0.037 13.4 18.1 0.091 12.1 18.1 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal RNA_pol_Rpc4 PF05132.14 GBG82067.1 - 0.054 13.9 19.0 0.11 13.0 19.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2981 PF11200.8 GBG82067.1 - 0.14 11.9 1.6 0.19 11.4 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Band_3_cyto PF07565.13 GBG82067.1 - 0.15 11.9 21.5 0.22 11.3 21.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4776 PF16003.5 GBG82067.1 - 0.17 10.9 34.0 0.22 10.5 34.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Otopetrin PF03189.13 GBG82067.1 - 0.24 10.2 4.0 0.38 9.5 4.0 1.3 1 0 0 1 1 1 0 Otopetrin Vfa1 PF08432.10 GBG82067.1 - 0.28 11.5 37.3 0.46 10.8 37.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4228 PF14009.6 GBG82067.1 - 0.29 11.5 14.4 0.54 10.6 14.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) SLC12 PF03522.15 GBG82067.1 - 0.51 9.3 23.3 0.72 8.8 23.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 GBG82067.1 - 0.57 7.2 13.9 0.75 6.8 13.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 GBG82067.1 - 0.7 8.5 6.2 0.84 8.2 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3_zeta PF05091.12 GBG82067.1 - 0.73 8.7 21.9 1.3 7.9 21.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 GBG82067.1 - 0.86 8.3 19.3 1.1 7.9 19.3 1.1 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.19 GBG82067.1 - 0.86 8.4 15.8 1.1 8.1 15.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SprA-related PF12118.8 GBG82067.1 - 1 8.5 16.7 1.3 8.0 16.7 1.1 1 0 0 1 1 1 0 SprA-related family AAA_11 PF13086.6 GBG82067.1 - 1.1 9.0 26.5 1.7 8.3 26.5 1.2 1 0 0 1 1 1 0 AAA domain Membralin PF09746.9 GBG82067.1 - 1.6 7.7 14.0 2.2 7.2 14.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein Asparaginase_2 PF01112.18 GBG82067.1 - 2.1 7.3 9.9 3.4 6.6 9.9 1.3 1 0 0 1 1 1 0 Asparaginase SRP-alpha_N PF04086.13 GBG82067.1 - 2.6 7.9 33.7 4.8 7.0 33.7 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NARP1 PF12569.8 GBG82067.1 - 3 6.6 35.4 4.7 6.0 35.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 GBG82067.1 - 3.4 6.8 12.5 4.6 6.4 12.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DAG_kinase_N PF14513.6 GBG82067.1 - 4.3 7.5 18.5 9.3 6.4 18.5 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus LicD PF04991.13 GBG82067.1 - 4.5 7.3 23.3 7.3 6.7 23.3 1.3 1 0 0 1 1 1 0 LicD family DUF2828 PF11443.8 GBG82067.1 - 5.1 5.1 26.9 7.3 4.6 26.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2052 PF09747.9 GBG82067.1 - 6.1 6.9 22.6 10 6.2 22.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 GBG82067.1 - 6.8 6.4 32.2 11 5.7 32.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.6 GBG82067.1 - 7 7.2 15.6 10 6.6 15.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Spt20 PF12090.8 GBG82067.1 - 7.6 6.1 21.0 12 5.4 21.0 1.2 1 0 0 1 1 1 0 Spt20 family SID-1_RNA_chan PF13965.6 GBG82067.1 - 8.6 4.6 7.3 15 3.8 7.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SDA1 PF05285.12 GBG82069.1 - 0.0085 15.6 26.0 0.013 14.9 26.0 1.3 1 0 0 1 1 1 1 SDA1 RNA_pol_Rpc4 PF05132.14 GBG82069.1 - 0.015 15.7 1.4 0.015 15.7 1.4 2.2 2 1 0 2 2 2 0 RNA polymerase III RPC4 Zip PF02535.22 GBG82069.1 - 0.019 14.2 0.9 0.026 13.8 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 GBG82069.1 - 0.022 13.0 36.2 0.034 12.4 36.2 1.2 1 0 0 1 1 1 0 Nop14-like family Pex14_N PF04695.13 GBG82069.1 - 0.038 14.6 0.0 0.24 12.1 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 GBG82069.1 - 0.067 13.0 11.9 0.12 12.2 11.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GBG82069.1 - 0.12 10.7 23.9 0.17 10.1 23.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 GBG82069.1 - 0.12 12.2 8.7 0.19 11.5 8.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein NARP1 PF12569.8 GBG82069.1 - 0.13 11.1 6.1 0.29 10.0 3.3 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 SpoIIP PF07454.11 GBG82069.1 - 0.17 11.3 8.4 0.018 14.5 4.0 1.5 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) HSP90 PF00183.18 GBG82069.1 - 0.23 10.3 14.8 0.34 9.7 14.8 1.2 1 0 0 1 1 1 0 Hsp90 protein Presenilin PF01080.17 GBG82069.1 - 0.28 9.9 5.9 0.4 9.4 5.9 1.2 1 0 0 1 1 1 0 Presenilin DUF3408 PF11888.8 GBG82069.1 - 0.47 10.6 15.0 0.26 11.4 11.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Connexin PF00029.19 GBG82069.1 - 0.83 9.4 5.1 1.4 8.7 5.1 1.3 1 0 0 1 1 1 0 Connexin DUF2151 PF10221.9 GBG82069.1 - 1.5 7.3 3.6 2.2 6.8 3.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF5523 PF17661.1 GBG82069.1 - 4.1 7.0 27.3 7.6 6.1 27.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) N6_N4_Mtase PF01555.18 GBG82070.1 - 7.5e-08 32.4 0.0 1.8e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 DNA methylase DUF659 PF04937.15 GBG82074.1 - 0.00022 21.1 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG82076.1 - 1.5e-06 28.5 0.9 1.6e-05 25.2 0.4 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG82077.1 - 1e-30 106.5 0.0 3.2e-29 101.6 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82077.1 - 3.3e-16 59.5 0.0 6.7e-16 58.5 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG82077.1 - 0.021 15.2 0.6 0.61 10.5 0.0 2.8 3 0 0 3 3 3 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG82077.1 - 0.025 14.2 0.4 3.4 7.3 0.1 2.9 3 0 0 3 3 3 0 Transposase DDE domain RVP_2 PF08284.11 GBG82079.1 - 0.047 13.5 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Nop14 PF04147.12 GBG82079.1 - 0.45 8.7 8.6 0.58 8.3 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG82079.1 - 0.81 9.1 9.9 1.2 8.5 9.9 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG82079.1 - 1.1 7.5 9.4 1.4 7.1 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG82080.1 - 2.7e-27 94.7 0.0 1.2e-26 92.6 0.0 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82080.1 - 4.4e-26 91.2 0.0 1.5e-25 89.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82080.1 - 6.4e-10 38.9 0.8 0.00014 21.4 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG82080.1 - 3.6e-07 30.7 0.0 8.5e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82080.1 - 3.7e-06 27.4 0.0 8.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG82080.1 - 7.1e-05 22.6 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG82080.1 - 0.00027 21.1 1.7 0.004 17.4 0.0 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG82080.1 - 0.00039 20.2 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG82080.1 - 0.072 12.2 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 CTP_transf_like PF01467.26 GBG82083.1 - 5.4e-24 85.0 0.1 3.3e-23 82.5 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF1564 PF07600.11 GBG82083.1 - 0.0071 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG82083.1 - 0.014 15.7 0.1 0.046 14.0 0.1 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein RVP_2 PF08284.11 GBG82084.1 - 3.5e-05 23.6 0.0 8.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG82084.1 - 6.1e-05 23.5 0.0 0.00019 21.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82084.1 - 0.00029 21.4 0.0 0.0011 19.5 0.0 2.0 2 1 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG82084.1 - 0.0095 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG82084.1 - 0.015 15.6 0.9 7.7 6.9 0.1 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein ABC_tran_Xtn PF12848.7 GBG82084.1 - 1 9.4 8.7 4.2 7.5 7.8 2.2 2 0 0 2 2 2 0 ABC transporter Myb_DNA-bind_4 PF13837.6 GBG82085.1 - 2.9e-11 43.6 1.2 8.1e-11 42.2 1.2 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG82085.1 - 0.0061 16.7 0.5 0.015 15.5 0.5 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82085.1 - 0.098 13.0 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG82085.1 - 0.1 12.8 0.8 0.43 10.9 0.3 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain HSP20 PF00011.21 GBG82087.1 - 1e-07 32.0 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG82087.1 - 0.038 13.6 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 HSP20-like domain found in ArsA HSP20 PF00011.21 GBG82088.1 - 4.2e-29 100.7 0.7 5.2e-29 100.4 0.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG82088.1 - 1.4e-08 34.2 0.5 2.4e-08 33.4 0.5 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 GBG82088.1 - 0.072 13.2 0.1 4.9 7.3 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal DUF659 PF04937.15 GBG82089.1 - 3.5e-31 108.1 0.0 5.4e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Herpes_DNAp_acc PF04929.12 GBG82089.1 - 2.5 7.0 3.8 3.4 6.5 3.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Myb_DNA-bind_4 PF13837.6 GBG82090.1 - 5.9e-18 65.0 3.5 9.3e-18 64.4 3.5 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG82090.1 - 0.0082 16.4 0.8 0.014 15.6 0.8 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82090.1 - 0.012 15.9 2.8 0.028 14.7 2.8 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG82090.1 - 0.025 14.7 0.1 0.044 14.0 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sporozoite_P67 PF05642.11 GBG82090.1 - 0.032 12.3 1.1 0.035 12.2 1.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RT_RNaseH_2 PF17919.1 GBG82092.1 - 1.9e-32 111.3 0.1 3.8e-32 110.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82092.1 - 4.1e-30 104.9 0.2 8e-30 104.0 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82092.1 - 2.7e-27 95.1 0.1 6e-27 94.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82092.1 - 1.3e-18 66.9 0.2 2.6e-18 65.8 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82092.1 - 4.5e-07 30.1 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82092.1 - 0.061 13.6 0.0 0.25 11.6 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger DUF659 PF04937.15 GBG82093.1 - 1.2e-46 158.3 1.0 2.3e-28 99.0 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG82094.1 - 9.7e-26 90.6 0.1 1.4e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82094.1 - 1.5e-14 53.9 0.0 3.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82094.1 - 1.8e-07 31.4 0.0 3.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG82095.1 - 1.2e-08 35.0 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG82095.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Nucleolin_bd PF16725.5 GBG82095.1 - 0.074 12.7 0.1 0.27 10.9 0.1 2.0 1 0 0 1 1 1 0 Nucleolin binding domain DUF659 PF04937.15 GBG82096.1 - 1.5e-25 89.9 0.2 4.4e-14 52.6 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) YlaC PF10777.9 GBG82096.1 - 0.14 12.0 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 Inner membrane protein YlaC Mucin PF01456.17 GBG82097.1 - 0.027 14.4 9.3 0.033 14.2 9.3 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein Myb_DNA-bind_4 PF13837.6 GBG82098.1 - 2.5e-10 40.6 0.2 4.3e-10 39.8 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82098.1 - 0.0034 17.7 0.3 0.0068 16.7 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG82098.1 - 0.01 15.9 1.1 0.017 15.2 1.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG82098.1 - 0.06 13.6 0.3 0.06 13.6 0.3 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain RVT_1 PF00078.27 GBG82101.1 - 9.5e-07 28.6 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG82101.1 - 3.2e-05 24.5 0.0 8.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82101.1 - 6e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG82101.1 - 0.00012 22.6 0.0 0.00034 21.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82101.1 - 0.006 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease CTP_transf_like PF01467.26 GBG82101.1 - 0.081 13.1 0.2 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Cytidylyltransferase-like FAM176 PF14851.6 GBG82102.1 - 1.2 8.8 7.4 3 7.5 7.4 1.6 1 0 0 1 1 1 0 FAM176 family DUF1772 PF08592.11 GBG82103.1 - 0.088 13.1 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DDE_Tnp_4 PF13359.6 GBG82104.1 - 2.2e-27 95.7 0.0 3.1e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82104.1 - 8.6e-11 41.8 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82104.1 - 0.0011 18.7 0.3 0.72 9.5 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain Pkinase_Tyr PF07714.17 GBG82106.1 - 3.2e-32 111.8 0.0 4.9e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82106.1 - 3.3e-26 92.2 0.0 7.4e-26 91.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG82106.1 - 0.00031 20.8 0.0 0.0023 17.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG82106.1 - 0.07 11.9 0.0 0.54 9.0 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase PD40 PF07676.12 GBG82106.1 - 0.18 11.8 0.8 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Pkinase_Tyr PF07714.17 GBG82107.1 - 2.8e-24 85.8 0.0 4.9e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82107.1 - 2.5e-19 69.7 0.0 6.3e-19 68.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 GBG82107.1 - 2.1e-09 37.8 4.4 0.0017 19.1 0.6 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 GBG82107.1 - 0.017 13.8 3.4 1.3 7.6 0.0 3.2 4 0 0 4 4 4 0 Nucleoporin Nup120/160 OSCP PF00213.18 GBG82107.1 - 0.4 10.8 9.8 5 7.2 3.4 2.5 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit Fib_alpha PF08702.10 GBG82107.1 - 6.1 7.0 18.1 13 6.0 1.7 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Cob_adeno_trans PF01923.18 GBG82107.1 - 6.4 6.9 11.5 4.4 7.4 1.5 2.6 1 1 1 2 2 2 0 Cobalamin adenosyltransferase WD40 PF00400.32 GBG82108.1 - 4.7e-09 36.7 1.1 0.0045 17.8 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 GBG82108.1 - 0.0055 15.4 0.1 1.1 7.9 0.0 3.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 DUF4746 PF15928.5 GBG82108.1 - 0.79 9.1 11.0 1.1 8.6 9.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Pkinase_Tyr PF07714.17 GBG82109.1 - 1e-36 126.6 0.0 5e-36 124.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82109.1 - 6.7e-34 117.4 0.0 1.1e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG82109.1 - 0.0059 16.6 0.1 0.014 15.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG82109.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 GBG82110.1 - 4.1e-36 124.6 0.0 1.8e-35 122.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82110.1 - 1.2e-33 116.7 0.0 2.4e-33 115.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 GBG82110.1 - 0.011 15.6 0.1 0.027 14.4 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG82110.1 - 0.049 12.4 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CcmD PF04995.14 GBG82110.1 - 4.2 7.5 5.0 0.7 10.0 0.1 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF963 PF06131.11 GBG82112.1 - 0.23 10.9 3.3 0.91 9.0 3.3 2.0 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Pkinase_Tyr PF07714.17 GBG82113.1 - 1.6e-35 122.7 0.0 7.1e-35 120.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82113.1 - 7.3e-33 114.0 0.0 1.2e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG82113.1 - 0.029 13.2 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4672 PF15716.5 GBG82113.1 - 0.063 12.9 0.4 0.17 11.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) DUF4381 PF14316.6 GBG82113.1 - 0.19 11.9 0.1 0.38 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pkinase_Tyr PF07714.17 GBG82114.1 - 5.2e-36 124.3 0.0 2e-35 122.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82114.1 - 6.7e-34 117.4 0.0 1e-33 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG82114.1 - 0.015 15.2 0.1 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG82114.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4381 PF14316.6 GBG82114.1 - 0.055 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FrhB_FdhB_C PF04432.13 GBG82116.1 - 0.14 12.0 1.8 13 5.6 0.2 2.7 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Nuc_N PF14448.6 GBG82116.1 - 1 9.3 10.1 10 6.1 0.1 4.6 4 1 0 4 4 4 0 Nuclease N terminal Tugs PF17840.1 GBG82116.1 - 1.5 9.1 8.4 2.1 8.6 0.3 3.6 3 0 0 3 3 3 0 Tethering Ubl4a to BAGS domain DUF4407 PF14362.6 GBG82116.1 - 8.1 5.7 44.7 0.015 14.7 7.9 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4407) PAN_4 PF14295.6 GBG82117.1 - 1.8e-06 27.7 6.1 1.8e-06 27.7 6.1 1.7 2 0 0 2 2 2 1 PAN domain SDA1 PF05285.12 GBG82118.1 - 1.5 8.2 24.9 1.9 7.8 24.9 1.1 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG82118.1 - 2.7 8.2 14.4 3.4 7.9 14.4 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG82118.1 - 9.9 4.2 24.5 13 3.8 24.5 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG82119.1 - 2e-11 43.9 0.0 3.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG82119.1 - 3.1e-07 30.2 0.0 8.3e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82119.1 - 9.2e-07 29.4 0.0 2.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82119.1 - 0.00024 21.6 0.0 0.0009 19.8 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG82119.1 - 0.022 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG82119.1 - 0.087 12.6 0.1 0.3 10.9 0.1 1.8 1 1 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG82120.1 - 7.2e-29 100.2 0.0 1.4e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82120.1 - 1.1e-21 76.7 0.0 2.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82120.1 - 7.7e-08 32.3 0.2 2.5e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain LMBR1 PF04791.16 GBG82120.1 - 0.24 10.2 4.3 0.41 9.5 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Phage_GPO PF05929.11 GBG82120.1 - 0.42 10.2 0.0 0.42 10.2 0.0 2.5 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4219 PF13961.6 GBG82120.1 - 0.46 10.2 1.6 0.7 9.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Vfa1 PF08432.10 GBG82120.1 - 1.2 9.5 16.0 2.2 8.6 16.0 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ICA69 PF04629.14 GBG82120.1 - 4.1 7.6 14.8 6.9 6.9 14.8 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain PA26 PF04636.13 GBG82120.1 - 5.1 5.9 8.6 4.2 6.2 7.1 1.5 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Myb_DNA-bind_4 PF13837.6 GBG82121.1 - 8.1e-11 42.2 4.5 1.8e-10 41.1 4.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG82121.1 - 0.0042 17.2 1.8 0.0098 16.1 1.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82121.1 - 0.0065 16.8 1.5 0.0065 16.8 1.5 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG82121.1 - 0.43 10.7 4.7 1.6 8.9 2.5 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain CDC45 PF02724.14 GBG82123.1 - 3.6e-05 22.3 19.6 3.8e-05 22.2 19.6 1.0 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GBG82123.1 - 0.00015 21.4 28.7 0.00015 21.4 28.7 1.1 1 0 0 1 1 1 1 SDA1 Drc1-Sld2 PF11719.8 GBG82123.1 - 0.004 16.8 13.4 0.004 16.8 13.4 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein Presenilin PF01080.17 GBG82123.1 - 0.025 13.3 13.2 0.024 13.4 13.2 1.0 1 0 0 1 1 1 0 Presenilin SpoIIIAH PF12685.7 GBG82123.1 - 0.027 14.3 12.1 0.027 14.3 12.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2151 PF10221.9 GBG82123.1 - 0.16 10.5 7.8 0.16 10.6 7.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 GBG82123.1 - 0.19 10.9 9.6 0.18 11.0 9.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 GBG82123.1 - 1.1 7.4 42.5 1.3 7.2 42.5 1.0 1 0 0 1 1 1 0 Nop14-like family Borrelia_P83 PF05262.11 GBG82123.1 - 2.2 6.7 14.8 2 6.8 14.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein API5 PF05918.11 GBG82123.1 - 3.3 6.4 10.5 4.3 6.0 10.5 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) BUD22 PF09073.10 GBG82123.1 - 3.4 6.9 34.4 4.1 6.6 34.4 1.1 1 0 0 1 1 1 0 BUD22 DDE_Tnp_4 PF13359.6 GBG82125.1 - 1.3e-28 99.6 0.0 1.9e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82125.1 - 2.1e-15 56.9 0.0 3.1e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82125.1 - 1.7e-06 27.8 5.4 0.0077 15.9 0.1 2.7 2 1 0 2 2 2 2 Transposase DDE domain SprT-like PF10263.9 GBG82125.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 SprT-like family YL1 PF05764.13 GBG82126.1 - 0.023 14.8 14.9 0.034 14.3 14.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nop53 PF07767.11 GBG82126.1 - 0.065 12.6 10.7 0.089 12.2 10.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.12 GBG82126.1 - 0.76 9.1 12.2 1 8.7 12.2 1.1 1 0 0 1 1 1 0 SDA1 Glyco_transf_64 PF09258.10 GBG82127.1 - 3.7e-45 154.1 0.0 5.4e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 GBG82127.1 - 1.4e-05 24.8 3.9 0.0028 17.3 3.9 2.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 CdiI_N PF18228.1 GBG82127.1 - 0.15 11.9 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 CdiI N-terminal domain Mannosyl_trans3 PF11051.8 GBG82127.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Ribosomal_60s PF00428.19 GBG82128.1 - 0.00022 21.8 9.5 0.00052 20.6 9.5 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein NOA36 PF06524.12 GBG82128.1 - 0.00087 18.7 14.5 0.00087 18.7 14.5 2.2 2 0 0 2 2 2 1 NOA36 protein RskA PF10099.9 GBG82128.1 - 0.0027 18.1 0.9 0.0037 17.6 0.9 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SDA1 PF05285.12 GBG82128.1 - 0.069 12.6 12.2 0.081 12.3 12.2 1.3 1 0 0 1 1 1 0 SDA1 DUF1676 PF07898.13 GBG82128.1 - 0.074 13.1 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) BAF1_ABF1 PF04684.13 GBG82128.1 - 0.62 9.1 13.6 0.82 8.7 13.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NPR3 PF03666.13 GBG82128.1 - 2.3 6.9 3.6 3.4 6.4 3.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Orf78 PF06024.12 GBG82128.1 - 2.5 8.5 4.2 1.9 8.8 2.7 1.7 1 1 0 1 1 1 0 Orf78 (ac78) DNA_pol_phi PF04931.13 GBG82128.1 - 9.9 4.1 28.3 13 3.8 28.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Beta_helix PF13229.6 GBG82129.1 - 1.3e-17 64.0 24.4 4.3e-07 29.9 1.3 4.7 2 2 2 4 4 4 4 Right handed beta helix region NosD PF05048.13 GBG82129.1 - 4.4e-07 29.4 2.1 0.2 10.9 0.6 4.6 2 2 2 4 4 4 4 Periplasmic copper-binding protein (NosD) DUF3648 PF12364.8 GBG82129.1 - 0.00059 20.1 2.1 0.7 10.1 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3648) DUF4131 PF13567.6 GBG82129.1 - 0.002 17.8 4.6 0.0045 16.7 4.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) Chlam_PMP PF02415.17 GBG82129.1 - 0.0078 16.6 50.8 1.9 9.1 0.1 12.7 14 0 0 14 14 14 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat GRDB PF07355.12 GBG82129.1 - 1.2 8.3 5.0 3.5 6.8 0.5 2.4 2 1 1 3 3 3 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) Beta_helix PF13229.6 GBG82131.1 - 9.5e-11 41.8 7.9 5.3e-06 26.4 4.6 2.3 1 1 1 2 2 2 2 Right handed beta helix region DUF4131 PF13567.6 GBG82131.1 - 0.036 13.7 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Chlam_PMP PF02415.17 GBG82131.1 - 0.057 13.9 28.6 3.1 8.5 0.1 7.9 9 0 0 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RVT_1 PF00078.27 GBG82132.1 - 8.5e-32 110.5 0.1 1.3e-31 109.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82132.1 - 1e-28 99.7 0.0 2.1e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82132.1 - 2.3e-28 98.1 0.0 1.4e-13 50.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82132.1 - 3.2e-15 56.0 1.3 6.7e-15 55.0 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG82132.1 - 1.9e-08 34.1 0.0 4.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG82132.1 - 0.00092 19.4 0.1 0.0026 17.9 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG82132.1 - 0.088 13.0 0.1 5.1 7.3 0.0 3.1 2 1 0 2 2 2 0 Integrase core domain RVT_3 PF13456.6 GBG82132.1 - 0.19 11.5 0.1 0.51 10.2 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.27 GBG82133.1 - 3.2e-30 105.3 0.1 5.1e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Beta_helix PF13229.6 GBG82133.1 - 6.1e-05 22.9 12.1 0.00039 20.3 9.4 2.4 1 1 1 2 2 2 2 Right handed beta helix region Chromo PF00385.24 GBG82133.1 - 8.7e-05 22.4 0.1 0.00016 21.5 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG82133.1 - 0.023 15.4 0.0 0.15 12.7 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease RVP_2 PF08284.11 GBG82133.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Chlam_PMP PF02415.17 GBG82133.1 - 1.6 9.4 27.7 4.3 8.0 0.1 6.1 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 GBG82134.1 - 1.2e-11 44.7 21.1 3.9e-08 33.3 8.8 2.5 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 GBG82134.1 - 0.033 13.5 3.5 0.083 12.1 2.6 2.2 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 GBG82134.1 - 1.9 9.2 28.3 0.85 10.2 0.2 6.8 6 1 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat rve PF00665.26 GBG82135.1 - 4.1e-05 23.7 0.0 6.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain SDA1 PF05285.12 GBG82135.1 - 0.84 9.0 20.3 1.2 8.5 20.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG82135.1 - 6.5 4.8 20.2 8.4 4.5 20.2 1.1 1 0 0 1 1 1 0 Nop14-like family Beta_helix PF13229.6 GBG82136.1 - 6.7e-06 26.0 11.9 0.0074 16.2 2.6 2.3 1 1 1 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG82136.1 - 0.62 10.7 40.0 0.45 11.1 0.6 7.4 6 2 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 GBG82137.1 - 2e-06 27.7 10.4 0.00064 19.6 7.0 2.7 1 1 1 2 2 2 2 Right handed beta helix region Beta_helix PF13229.6 GBG82138.1 - 2.8e-07 30.5 14.1 0.0014 18.5 14.1 2.7 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG82138.1 - 0.1 11.9 5.5 0.38 10.0 3.5 2.5 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 GBG82138.1 - 0.22 12.1 39.4 0.83 10.3 0.5 7.8 7 2 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF659 PF04937.15 GBG82139.1 - 2.1e-37 128.3 0.0 4e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG82139.1 - 6e-12 45.6 0.0 1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG82139.1 - 0.092 12.9 0.0 0.83 9.9 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain Ldl_recept_a PF00057.18 GBG82140.1 - 7e-43 144.6 138.3 1.3e-09 38.1 8.2 11.8 12 0 0 12 12 12 10 Low-density lipoprotein receptor domain class A BUD22 PF09073.10 GBG82141.1 - 8 5.7 31.7 11 5.2 31.7 1.1 1 0 0 1 1 1 0 BUD22 cNMP_binding PF00027.29 GBG82142.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DDE_Tnp_4 PF13359.6 GBG82143.1 - 2e-23 82.8 0.0 4.1e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82143.1 - 1.3e-16 60.9 0.0 2.4e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Integrase_H2C2 PF17921.1 GBG82143.1 - 1.1e-07 31.9 0.3 3.8e-07 30.1 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain SDA1 PF05285.12 GBG82143.1 - 0.0018 17.8 25.0 0.0032 16.9 25.0 1.3 1 0 0 1 1 1 1 SDA1 zf-H2C2 PF09337.10 GBG82143.1 - 0.0042 17.3 0.1 0.013 15.7 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger CDC45 PF02724.14 GBG82143.1 - 0.069 11.4 18.4 0.1 10.9 18.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG82143.1 - 0.12 10.6 29.0 0.18 10.0 29.0 1.2 1 0 0 1 1 1 0 Nop14-like family DDE_Tnp_1 PF01609.21 GBG82143.1 - 0.27 10.8 2.3 25 4.4 0.0 3.3 3 0 0 3 3 3 0 Transposase DDE domain SAPS PF04499.15 GBG82143.1 - 0.29 9.9 5.5 0.4 9.4 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 GBG82143.1 - 5.8 6.0 6.4 9.2 5.4 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Myb_DNA-bind_4 PF13837.6 GBG82144.1 - 3.2e-11 43.4 1.5 5.3e-11 42.7 1.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4573 PF15140.6 GBG82144.1 - 0.0096 15.7 14.3 0.017 14.9 14.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) MADF_DNA_bdg PF10545.9 GBG82144.1 - 0.027 14.8 0.2 0.049 13.9 0.2 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG82144.1 - 0.029 14.4 2.0 0.053 13.6 2.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Beta_helix PF13229.6 GBG82145.1 - 3.5e-12 46.5 13.8 5.2e-09 36.1 6.7 2.9 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 GBG82145.1 - 0.00019 20.8 2.2 0.015 14.6 1.1 2.3 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Ldl_recept_a PF00057.18 GBG82146.1 - 2.8e-30 104.2 73.5 5.8e-10 39.2 6.7 7.3 5 3 2 8 8 8 6 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 GBG82147.1 - 5.5e-45 151.3 147.5 8.7e-07 29.1 9.0 12.2 10 1 2 12 12 12 11 Low-density lipoprotein receptor domain class A RVP_2 PF08284.11 GBG82148.1 - 0.0032 17.2 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG82148.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein SlyX PF04102.12 GBG82148.1 - 0.14 12.8 6.6 0.45 11.2 0.6 2.7 3 0 0 3 3 3 0 SlyX DUF1664 PF07889.12 GBG82148.1 - 0.27 11.3 0.5 0.9 9.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 GBG82148.1 - 0.33 11.0 4.4 0.7 10.0 4.4 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation ATG16 PF08614.11 GBG82148.1 - 1.8 8.8 5.4 4 7.6 5.4 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CHRD PF07452.12 GBG82150.1 - 8e-14 52.6 0.0 1.3e-13 51.9 0.0 1.4 1 0 0 1 1 1 1 CHRD domain ABC_tran_CTD PF16326.5 GBG82151.1 - 0.018 15.3 0.7 0.089 13.1 0.7 2.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain HALZ PF02183.18 GBG82151.1 - 0.055 13.7 1.2 0.055 13.7 1.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 GBG82151.1 - 2.2 8.1 8.7 0.1 12.4 2.2 2.1 3 0 0 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 GBG82151.1 - 3.3 7.9 10.0 0.076 13.1 2.1 2.4 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 GBG82151.1 - 4.8 7.4 7.8 0.26 11.4 1.4 2.1 2 0 0 2 2 2 0 bZIP transcription factor Myb_DNA-bind_4 PF13837.6 GBG82152.1 - 1.4e-10 41.4 0.1 2.6e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG82152.1 - 0.046 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82152.1 - 0.086 13.2 0.4 0.23 11.8 0.3 1.7 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVT_1 PF00078.27 GBG82153.1 - 0.054 13.0 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2014 PF09427.10 GBG82153.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Toprim_N PF08275.11 GBG82153.1 - 0.11 12.6 0.0 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 DNA primase catalytic core, N-terminal domain PMBR PF09373.10 GBG82153.1 - 0.14 12.3 0.0 0.64 10.3 0.0 2.2 1 1 1 2 2 2 0 Pseudomurein-binding repeat HTH_12 PF08461.10 GBG82156.1 - 0.0048 16.8 5.3 36 4.4 0.1 6.2 2 1 7 9 9 9 0 Ribonuclease R winged-helix domain RTA1 PF04479.13 GBG82156.1 - 0.011 15.3 15.3 33 4.0 0.0 8.0 2 2 7 9 9 9 0 RTA1 like protein Methyltransf_1N PF02870.15 GBG82156.1 - 0.072 13.9 3.8 18 6.3 0.0 4.9 3 1 1 5 5 5 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain YjhX_toxin PF09857.9 GBG82156.1 - 0.12 12.4 1.1 4.2 7.4 0.0 3.6 2 2 0 3 3 3 0 Putative toxin of bacterial toxin-antitoxin pair PapC_C PF13953.6 GBG82156.1 - 0.71 9.7 31.5 29 4.6 0.3 8.4 1 1 10 11 11 11 0 PapC C-terminal domain FBA_3 PF08268.12 GBG82156.1 - 1.2 9.0 10.4 4.6 7.2 0.1 4.3 1 1 4 6 6 6 0 F-box associated domain RT_RNaseH_2 PF17919.1 GBG82157.1 - 1.2e-23 83.1 0.0 2.4e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82157.1 - 1.3e-21 76.8 0.0 3.2e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG82157.1 - 9.6e-17 61.3 0.0 2.2e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG82157.1 - 2.5e-13 49.9 0.0 6.7e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG82157.1 - 0.0036 17.0 0.0 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 GBG82158.1 - 1.1e-08 35.3 0.0 2.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG82158.1 - 0.0021 18.6 0.0 0.0048 17.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG82158.1 - 0.0078 16.0 0.0 0.04 13.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG82158.1 - 0.0098 16.5 0.0 0.024 15.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG82158.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG82159.1 - 0.0025 17.4 0.0 0.008 15.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG82159.1 - 0.24 11.7 1.7 1.1 9.6 0.5 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG82160.1 - 2.4e-06 27.8 0.0 4.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82160.1 - 4.8e-05 23.3 0.0 9.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ku_N PF03731.15 GBG82160.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain zf-C3Hc3H PF13891.6 GBG82161.1 - 7.7e-13 48.6 1.4 2.5e-12 47.0 1.4 2.0 1 0 0 1 1 1 1 Potential DNA-binding domain AP2 PF00847.20 GBG82161.1 - 3.3e-07 30.4 0.1 1.8e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 AP2 domain N6_N4_Mtase PF01555.18 GBG82162.1 - 1.8e-05 24.6 0.0 2.9e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 DNA methylase PBP1_TM PF14812.6 GBG82165.1 - 0.0048 17.2 2.6 0.0063 16.8 2.6 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-R PF06729.12 GBG82165.1 - 0.032 14.2 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore component, CENP-R DARPP-32 PF05395.12 GBG82165.1 - 0.045 14.0 9.9 0.048 13.9 9.9 1.0 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 PTPRCAP PF15713.5 GBG82165.1 - 0.062 13.6 11.7 0.074 13.3 11.7 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Sulfotransfer_3 PF13469.6 GBG82165.1 - 0.13 12.6 0.1 0.14 12.5 0.1 1.1 1 0 0 1 1 1 0 Sulfotransferase family efThoc1 PF11957.8 GBG82165.1 - 0.2 10.3 2.4 0.23 10.1 2.4 1.0 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor DUF4746 PF15928.5 GBG82165.1 - 0.34 10.3 8.2 0.38 10.1 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2428 PF10350.9 GBG82165.1 - 0.37 10.0 2.2 0.43 9.8 2.2 1.0 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) TRAP_alpha PF03896.16 GBG82165.1 - 0.44 9.7 8.3 0.47 9.6 8.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit THOC2_N PF16134.5 GBG82165.1 - 0.45 9.1 3.2 0.48 9.0 3.2 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DNA_pol_phi PF04931.13 GBG82165.1 - 0.49 8.4 19.5 0.53 8.3 19.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GBG82165.1 - 0.58 9.4 16.3 0.6 9.4 16.3 1.0 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 GBG82165.1 - 0.67 9.9 6.8 0.79 9.6 6.8 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 GBG82165.1 - 1 7.5 16.0 1.1 7.4 16.0 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 GBG82165.1 - 1.1 7.8 7.2 1.1 7.7 7.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mpp10 PF04006.12 GBG82165.1 - 1.3 7.3 14.6 1.5 7.1 14.6 1.0 1 0 0 1 1 1 0 Mpp10 protein BSP_II PF05432.11 GBG82165.1 - 2.1 7.9 18.7 2.8 7.5 18.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pox_Ag35 PF03286.14 GBG82165.1 - 2.7 7.7 7.8 3.1 7.5 7.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FRQ PF09421.10 GBG82165.1 - 2.9 5.8 6.2 3.2 5.7 6.2 1.0 1 0 0 1 1 1 0 Frequency clock protein Radial_spoke PF04712.12 GBG82165.1 - 4.3 6.2 11.8 4.5 6.1 11.8 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein XAP5 PF04921.14 GBG82165.1 - 4.3 7.1 8.1 4.8 6.9 8.1 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator Sigma70_ner PF04546.13 GBG82165.1 - 5.7 6.8 14.6 6.7 6.5 14.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.18 GBG82165.1 - 6.6 6.5 9.4 8.3 6.2 9.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Nop53 PF07767.11 GBG82165.1 - 7.4 5.9 12.4 8.1 5.7 12.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2457 PF10446.9 GBG82165.1 - 7.5 5.6 18.4 8.2 5.5 18.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.12 GBG82165.1 - 7.6 5.8 16.1 8.4 5.7 16.1 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 GBG82165.1 - 8.6 5.6 12.7 9.6 5.4 12.7 1.0 1 0 0 1 1 1 0 BUD22 Myb_DNA-binding PF00249.31 GBG82166.1 - 4.8e-21 74.7 0.1 5.1e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG82166.1 - 1.3e-05 25.3 1.2 0.00046 20.4 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GBG82166.1 - 0.12 12.3 0.1 0.71 9.8 0.1 2.0 2 0 0 2 2 2 0 Myb DNA-binding like gag-asp_proteas PF13975.6 GBG82167.1 - 3e-06 27.7 0.0 6.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82167.1 - 5.9e-05 23.6 0.0 0.00016 22.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82167.1 - 0.0044 16.8 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82167.1 - 0.0051 16.6 0.0 0.0075 16.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG82167.1 - 0.12 12.0 0.2 0.25 11.0 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG82167.1 - 0.51 10.5 2.1 0.92 9.7 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle MT-A70 PF05063.14 GBG82168.1 - 1.1e-33 116.6 0.1 1.4e-22 80.4 0.0 2.7 2 0 0 2 2 2 2 MT-A70 LCAT PF02450.15 GBG82169.1 - 0.00083 18.6 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase HSP90 PF00183.18 GBG82169.1 - 0.11 11.4 4.6 0.15 10.9 4.6 1.1 1 0 0 1 1 1 0 Hsp90 protein RPN2_C PF18004.1 GBG82169.1 - 3.4 7.5 8.7 5.7 6.8 8.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 GBG82169.1 - 7.5 4.6 12.3 11 4.1 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG82170.1 - 4e-30 105.0 0.1 7.3e-30 104.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82170.1 - 5.6e-28 96.9 0.0 1.2e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82170.1 - 1.7e-25 89.3 0.1 3.8e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82170.1 - 4.1e-16 58.8 0.1 1.1e-14 54.2 0.1 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG82170.1 - 1.9e-13 50.7 0.0 3.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82170.1 - 0.0016 18.6 0.0 0.01 16.0 0.0 2.4 2 0 0 2 2 2 1 H2C2 zinc finger Rhamno_transf PF11316.8 GBG82170.1 - 0.044 13.2 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase RVT_1 PF00078.27 GBG82171.1 - 3.4e-30 105.2 0.1 6e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82171.1 - 1.8e-23 82.4 0.0 4.1e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82171.1 - 3.2e-20 72.4 0.0 7.2e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82171.1 - 3.9e-12 46.1 0.3 1.6e-11 44.1 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG82171.1 - 0.0004 20.6 0.2 0.0021 18.3 0.2 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein Baculo_PEP_C PF04513.12 GBG82171.1 - 0.031 14.3 0.8 0.13 12.3 0.8 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-H2C2 PF09337.10 GBG82171.1 - 0.081 13.2 0.1 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger ERM PF00769.19 GBG82171.1 - 0.43 10.4 4.5 0.68 9.7 4.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MscS_TM PF12794.7 GBG82171.1 - 3.6 6.3 5.7 7.3 5.3 5.7 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 MraZ PF02381.18 GBG82172.1 - 0.025 14.5 0.1 0.049 13.6 0.1 1.4 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like Pkinase_Tyr PF07714.17 GBG82173.1 - 3.6e-17 62.5 0.0 6.7e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82173.1 - 1.3e-08 34.6 0.0 3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TFIIA PF03153.13 GBG82173.1 - 0.24 11.3 22.7 0.015 15.4 17.1 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spaetzle PF16077.5 GBG82173.1 - 1.3 9.6 12.1 2.7 8.6 12.1 1.5 1 0 0 1 1 1 0 Spaetzle DUF659 PF04937.15 GBG82174.1 - 1e-18 67.7 0.0 1.6e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Remorin_C PF03763.13 GBG82175.1 - 8e-09 35.3 29.0 2.3e-08 33.8 29.0 1.8 1 0 0 1 1 1 1 Remorin, C-terminal region GBP_C PF02841.14 GBG82175.1 - 0.62 9.4 17.5 1.4 8.3 17.5 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Myb_DNA-bind_4 PF13837.6 GBG82177.1 - 9e-28 96.5 2.6 7.8e-13 48.6 0.1 2.4 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82177.1 - 1.2e-09 38.3 3.9 0.00085 19.6 0.2 2.8 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG82177.1 - 1.1e-07 31.8 8.8 0.001 19.1 1.1 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG82177.1 - 2.4e-05 24.4 2.5 0.011 15.9 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Scm3 PF10384.9 GBG82177.1 - 0.00059 19.5 1.9 4.7 7.0 0.0 3.8 3 0 0 3 3 3 2 Centromere protein Scm3 Apt1 PF10351.9 GBG82177.1 - 0.033 13.1 6.0 0.15 10.9 0.3 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain ASFV_J13L PF05568.11 GBG82177.1 - 2.5 7.8 10.4 7.2 6.3 10.4 1.7 1 0 0 1 1 1 0 African swine fever virus J13L protein CPSF100_C PF13299.6 GBG82177.1 - 6.9 6.8 11.2 1.2 9.3 4.5 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal WD40 PF00400.32 GBG82178.1 - 1.8e-23 82.3 5.7 1.2e-07 32.2 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Sof1 PF04158.14 GBG82178.1 - 2.6e-11 43.6 0.2 5.1e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 Sof1-like domain Rhomboid PF01694.22 GBG82180.1 - 1.5e-26 93.2 13.7 1.5e-26 93.2 13.7 1.8 3 0 0 3 3 3 1 Rhomboid family Holin_BlyA PF05102.12 GBG82180.1 - 0.17 11.9 2.4 0.2 11.6 0.1 2.1 2 0 0 2 2 2 0 holin, BlyA family gag-asp_proteas PF13975.6 GBG82181.1 - 0.0028 18.2 0.0 0.0059 17.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG82181.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82181.1 - 0.12 13.0 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG82181.1 - 0.27 11.4 2.6 0.5 10.5 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG82182.1 - 1.6e-21 76.5 0.0 3.5e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82182.1 - 1e-20 73.7 0.0 2.1e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82182.1 - 3.7e-11 42.9 0.2 2.1e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG82182.1 - 8.2e-10 38.6 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Proteasome PF00227.26 GBG82184.1 - 8.5e-48 162.4 0.1 1.1e-47 162.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit AroM PF07302.11 GBG82184.1 - 0.073 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 AroM protein Dimer_Tnp_hAT PF05699.14 GBG82185.1 - 2.6e-07 30.4 0.1 5e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2783 PF10932.8 GBG82185.1 - 0.094 12.4 1.8 9.5 6.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2783) Rhomboid PF01694.22 GBG82186.1 - 1.9e-26 92.8 12.8 1.9e-26 92.8 12.8 1.6 2 0 0 2 2 2 1 Rhomboid family Holin_BlyA PF05102.12 GBG82186.1 - 0.14 12.2 0.1 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 holin, BlyA family Pox_A14 PF05767.12 GBG82186.1 - 1 9.6 3.0 1.2 9.3 0.2 2.4 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 T_cell_tran_alt PF15128.6 GBG82186.1 - 2.4 8.0 4.2 1.4 8.8 0.8 2.2 3 0 0 3 3 3 0 T-cell leukemia translocation-altered PPR_2 PF13041.6 GBG82187.1 - 2.9e-103 338.0 4.7 2.9e-11 43.4 0.0 13.0 4 3 9 13 13 13 13 PPR repeat family PPR PF01535.20 GBG82187.1 - 6.8e-80 257.9 19.0 6.6e-07 29.2 0.1 14.8 15 0 0 15 15 15 13 PPR repeat PPR_3 PF13812.6 GBG82187.1 - 2.1e-75 248.7 0.0 1.1e-15 57.5 0.1 9.0 5 3 4 9 9 9 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG82187.1 - 5.9e-72 237.0 0.0 2.2e-05 24.0 0.0 14.4 14 0 0 14 14 14 12 PPR repeat PPR_long PF17177.4 GBG82187.1 - 1e-38 132.8 0.0 8.2e-19 67.8 0.0 4.3 2 2 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 GBG82187.1 - 1.2e-11 43.7 1.8 0.59 10.3 0.0 8.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG82187.1 - 8e-11 41.8 3.6 5.2 8.2 0.1 10.3 8 3 3 11 11 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG82187.1 - 5.9e-08 33.1 0.0 0.74 10.4 0.0 6.5 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 GBG82187.1 - 1.6e-06 28.3 8.9 0.69 10.3 0.4 6.8 6 2 1 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG82187.1 - 6.5e-05 23.1 0.5 5.8 7.2 0.1 5.4 6 1 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 GBG82187.1 - 0.00057 19.6 1.2 6.8 6.7 0.1 6.4 8 0 0 8 8 6 1 Tetratricopeptide repeat BTAD PF03704.17 GBG82187.1 - 0.002 18.6 7.7 0.31 11.5 0.3 5.4 4 2 3 7 7 6 1 Bacterial transcriptional activator domain ECSIT PF06239.11 GBG82187.1 - 0.0032 16.6 0.2 1.5 7.9 0.0 4.5 3 2 3 6 6 6 1 Evolutionarily conserved signalling intermediate in Toll pathway ATP13 PF12921.7 GBG82187.1 - 0.0057 16.5 0.0 3.7 7.5 0.0 4.3 3 1 1 4 4 4 1 Mitochondrial ATPase expression COX5A PF02284.16 GBG82187.1 - 0.0067 16.4 0.0 0.62 10.1 0.0 3.4 3 1 0 4 4 4 1 Cytochrome c oxidase subunit Va TPR_2 PF07719.17 GBG82187.1 - 0.0087 16.1 7.9 43 4.6 0.1 7.7 10 0 0 10 10 9 0 Tetratricopeptide repeat MRP-S27 PF10037.9 GBG82187.1 - 0.012 14.5 0.0 3.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_4 PF07721.14 GBG82187.1 - 0.019 15.5 4.0 35 5.4 0.0 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Clathrin PF00637.20 GBG82187.1 - 0.023 14.6 0.0 24 4.8 0.0 4.4 4 1 1 5 5 5 0 Region in Clathrin and VPS TPR_15 PF13429.6 GBG82187.1 - 0.074 12.3 0.0 20 4.3 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Radical_SAM PF04055.21 GBG82187.1 - 0.088 13.2 0.0 8.7 6.7 0.0 3.2 2 1 0 3 3 3 0 Radical SAM superfamily PYRIN PF02758.16 GBG82187.1 - 0.2 11.8 0.2 14 5.9 0.0 3.9 4 0 0 4 4 3 0 PAAD/DAPIN/Pyrin domain SR-25 PF10500.9 GBG82187.1 - 0.66 9.5 12.4 1.1 8.8 12.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Integrase_H2C2 PF17921.1 GBG82188.1 - 1.5e-15 57.0 0.2 3.2e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82188.1 - 1.3e-14 54.4 0.0 2.5e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82188.1 - 0.0004 20.5 0.0 0.00088 19.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DprA_WH PF17782.1 GBG82191.1 - 0.085 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 DprA winged helix domain RVT_1 PF00078.27 GBG82192.1 - 8.6e-20 71.2 0.0 1.6e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PerC PF06069.11 GBG82192.1 - 0.15 12.3 2.0 1.5 9.1 0.8 2.9 3 0 0 3 3 3 0 PerC transcriptional activator Myb_DNA-bind_4 PF13837.6 GBG82193.1 - 1e-09 38.7 0.6 1.4e-08 35.0 0.5 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG82193.1 - 0.011 15.8 1.7 0.03 14.4 1.7 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG82194.1 - 6.1e-33 113.7 0.0 1.6e-32 112.3 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82194.1 - 7.6e-14 51.8 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82194.1 - 0.016 14.9 0.1 8 6.0 0.0 3.0 3 0 0 3 3 3 0 Transposase DDE domain HTH_48 PF17906.1 GBG82194.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Pex2_Pex12 PF04757.14 GBG82195.1 - 4.8e-27 95.0 0.0 3e-17 63.0 0.0 2.2 2 0 0 2 2 2 2 Pex2 / Pex12 amino terminal region RT_RNaseH_2 PF17919.1 GBG82196.1 - 5.7e-34 116.1 0.0 1.1e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82196.1 - 1.1e-28 100.3 0.1 2.1e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82196.1 - 1.5e-28 99.2 0.1 3.1e-28 98.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG82196.1 - 5.6e-14 52.4 0.1 1.3e-13 51.2 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG82196.1 - 0.034 13.8 0.6 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-CCHC PF00098.23 GBG82198.1 - 5.7e-08 32.5 0.6 1.4e-07 31.3 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG82198.1 - 0.018 14.9 1.1 0.039 13.8 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle bHLH-MYC_N PF14215.6 GBG82198.1 - 0.019 15.3 1.9 0.036 14.3 1.9 1.5 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal zf-CCHC_4 PF14392.6 GBG82198.1 - 0.078 12.7 0.8 0.23 11.2 0.8 1.9 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG82199.1 - 3e-11 43.5 4.0 4.6e-11 43.0 4.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG82199.1 - 0.091 13.0 0.7 0.18 12.0 0.7 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain SDA1 PF05285.12 GBG82200.1 - 0.081 12.3 11.0 0.084 12.3 11.0 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG82200.1 - 0.34 10.2 10.9 0.35 10.1 10.9 1.1 1 0 0 1 1 1 0 BUD22 Dicty_REP PF05086.12 GBG82200.1 - 0.68 7.9 2.9 0.7 7.8 2.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PPP4R2 PF09184.11 GBG82200.1 - 1.2 8.7 8.2 1.3 8.5 8.2 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GBG82200.1 - 1.4 7.0 13.3 1.7 6.8 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG82200.1 - 2.5 7.4 12.8 3.5 6.9 12.8 1.3 1 0 0 1 1 1 0 NOA36 protein TPR_9 PF13371.6 GBG82201.1 - 2e-06 27.8 0.8 0.0031 17.6 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG82201.1 - 0.00047 20.1 0.7 0.41 10.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG82201.1 - 0.0012 19.3 0.0 0.29 11.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG82201.1 - 0.41 11.3 0.0 0.41 11.3 0.0 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.6 GBG82202.1 - 5.3e-07 29.9 0.2 2e-06 28.1 0.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG82202.1 - 0.00072 19.6 0.2 0.0018 18.3 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG82203.1 - 1.1e-25 90.1 0.0 1.6e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82203.1 - 2e-13 50.4 0.0 3.6e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82203.1 - 0.0069 16.0 0.2 0.89 9.2 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain Sugar_tr PF00083.24 GBG82205.1 - 5.5e-94 315.6 28.8 6.6e-94 315.3 28.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GBG82205.1 - 7.3e-25 87.6 45.1 7.3e-25 87.6 45.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_3 PF00202.21 GBG82206.1 - 1.2e-113 379.8 0.0 1.4e-113 379.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GBG82206.1 - 2.7e-05 23.5 0.1 4.8e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II OAM_dimer PF16554.5 GBG82206.1 - 0.067 13.6 0.0 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase RVT_1 PF00078.27 GBG82208.1 - 2.7e-25 89.2 0.1 4e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG82208.1 - 0.0081 15.9 0.0 0.032 14.0 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG82210.1 - 2.1e-06 28.2 0.0 6.2e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82210.1 - 8.1e-05 23.2 0.0 0.00023 21.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82210.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG82210.1 - 0.01 15.5 0.3 0.022 14.4 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVP_2 PF08284.11 GBG82210.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease 7TM_GPCR_Srz PF10325.9 GBG82213.1 - 0.19 11.0 0.6 0.26 10.6 0.6 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz DUF2057 PF09829.9 GBG82214.1 - 0.016 15.4 0.2 0.025 14.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) gag-asp_proteas PF13975.6 GBG82215.1 - 2.2e-07 31.3 0.1 7.4e-07 29.6 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82215.1 - 1.6e-05 25.4 0.1 3.8e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82215.1 - 0.00044 20.0 0.1 0.00082 19.2 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82215.1 - 0.029 14.1 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG82215.1 - 0.055 13.6 1.9 0.14 12.3 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG82215.1 - 0.065 12.9 1.7 0.07 12.8 0.2 1.8 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like DUF3216 PF11505.8 GBG82215.1 - 0.092 13.0 1.3 16 5.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) TPR_1 PF00515.28 GBG82216.1 - 3.1e-09 36.3 0.4 0.00018 21.1 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG82216.1 - 8.3e-08 31.8 1.4 0.019 15.1 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG82216.1 - 1.6e-07 30.9 0.1 5.5e-06 26.0 0.0 2.5 1 1 1 2 2 2 1 TPR repeat TPR_7 PF13176.6 GBG82216.1 - 6.8e-06 25.8 0.2 0.14 12.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG82216.1 - 5.6e-05 23.3 0.8 0.00027 21.2 0.8 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG82216.1 - 0.0015 18.3 0.3 1.4 8.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Sel1 PF08238.12 GBG82216.1 - 0.0075 16.9 0.1 1.5 9.6 0.2 2.6 2 0 0 2 2 2 1 Sel1 repeat TPR_8 PF13181.6 GBG82216.1 - 0.039 14.2 1.8 0.99 9.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG82216.1 - 0.042 14.5 0.5 0.042 14.5 0.5 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG82216.1 - 0.091 13.6 4.0 2.3 9.3 0.1 3.5 3 1 1 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG82216.1 - 0.19 12.0 1.7 0.19 12.0 0.3 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PRP21_like_P PF12230.8 GBG82216.1 - 7.2 6.4 12.8 0.085 12.7 0.7 2.8 2 1 1 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Guanylate_kin PF00625.21 GBG82218.1 - 0.023 14.4 0.2 0.023 14.4 0.2 2.1 2 0 0 2 2 2 0 Guanylate kinase KapB PF08810.10 GBG82218.1 - 0.057 13.6 1.1 0.16 12.2 1.1 1.7 1 0 0 1 1 1 0 Kinase associated protein B DUF3037 PF11236.8 GBG82218.1 - 4.6 7.7 9.6 14 6.1 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3037) CENP-F_leu_zip PF10473.9 GBG82218.1 - 6.4 6.8 23.2 11 6.0 19.5 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFP_35_N PF07334.13 GBG82218.1 - 9.2 6.4 7.7 0.86 9.7 1.6 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PI3_PI4_kinase PF00454.27 GBG82219.1 - 6.8e-34 117.8 0.0 7.3e-26 91.5 0.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GBG82219.1 - 9.7e-08 31.6 0.3 1.7e-07 30.9 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) rve PF00665.26 GBG82220.1 - 1.3e-07 31.8 0.1 7.9e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain DUF3138 PF11336.8 GBG82220.1 - 0.37 9.4 2.1 0.6 8.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) REV PF00424.18 GBG82220.1 - 3.3 7.8 6.1 1.2 9.2 1.3 2.5 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Carb_anhydrase PF00194.21 GBG82221.1 - 4.4e-30 105.0 0.0 1.5e-29 103.3 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Lipoxygenase PF00305.19 GBG82222.1 - 3.2e-105 353.0 0.0 1e-97 328.3 0.0 3.3 1 1 2 3 3 3 3 Lipoxygenase RVT_1 PF00078.27 GBG82223.1 - 1.8e-25 89.8 0.1 3.8e-25 88.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82223.1 - 6.5e-24 84.2 0.0 1.5e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82223.1 - 2.5e-23 82.0 0.0 7.4e-23 80.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82223.1 - 1.2e-20 73.3 0.3 2.5e-20 72.3 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG82223.1 - 3.2e-06 27.0 0.0 9.3e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82223.1 - 3.8e-06 27.4 0.0 9.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82223.1 - 0.0022 18.5 0.0 0.0065 17.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG82223.1 - 0.0033 17.6 0.0 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG82223.1 - 0.087 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG82223.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger SlyX PF04102.12 GBG82223.1 - 0.12 13.0 4.7 1.2 9.8 0.3 3.4 3 0 0 3 3 3 0 SlyX TolA_bind_tri PF16331.5 GBG82223.1 - 0.13 12.3 3.8 0.27 11.4 3.8 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation RT_RNaseH_2 PF17919.1 GBG82225.1 - 1.1e-24 86.4 0.0 1.6e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82225.1 - 6.1e-21 74.7 0.0 1e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82225.1 - 1.1e-14 54.5 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lipoxygenase PF00305.19 GBG82226.1 - 8.2e-113 378.1 0.0 4.4e-108 362.5 0.0 2.6 1 1 1 2 2 2 2 Lipoxygenase Sas10 PF09368.10 GBG82228.1 - 2.4e-25 88.8 5.3 2.4e-25 88.8 5.3 3.4 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 GBG82228.1 - 2.1e-18 66.7 0.2 2.1e-18 66.7 0.2 2.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Rad21_Rec8 PF04824.16 GBG82230.1 - 5e-15 54.5 0.0 9.1e-15 53.7 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein RPN2_C PF18004.1 GBG82230.1 - 0.07 13.0 8.8 0.14 12.0 8.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain GPR15L PF15854.5 GBG82230.1 - 0.16 12.2 0.1 0.34 11.2 0.1 1.6 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Radial_spoke PF04712.12 GBG82230.1 - 0.16 10.9 9.6 0.26 10.2 9.6 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DUF2615 PF11027.8 GBG82230.1 - 0.67 10.1 0.0 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Nop14 PF04147.12 GBG82230.1 - 0.86 7.7 13.4 1.2 7.2 13.4 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG82230.1 - 1.1 9.0 11.2 2.3 8.0 11.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 GBG82230.1 - 1.7 7.8 5.7 3.2 6.9 5.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 GBG82230.1 - 2.4 7.9 7.2 4.2 7.1 6.3 1.8 2 0 0 2 2 2 0 Connexin TRAP_alpha PF03896.16 GBG82230.1 - 2.6 7.2 11.1 8.7 5.5 10.4 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TFB6 PF17110.5 GBG82230.1 - 4.1 7.1 8.6 7.4 6.3 8.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TERB2 PF15101.6 GBG82230.1 - 6.7 6.7 6.8 11 6.0 6.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Serinc PF03348.15 GBG82230.1 - 7 5.5 6.5 0.66 8.8 1.9 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) Presenilin PF01080.17 GBG82230.1 - 7.1 5.3 9.3 9.7 4.8 8.2 1.7 2 0 0 2 2 2 0 Presenilin DUF4834 PF16118.5 GBG82230.1 - 9.8 7.2 12.8 14 6.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) NPR3 PF03666.13 GBG82230.1 - 9.8 4.8 7.0 17 4.0 7.0 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RVT_1 PF00078.27 GBG82231.1 - 1.6e-06 27.8 0.1 0.0024 17.5 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG82231.1 - 1.4e-05 24.9 2.9 4.2e-05 23.4 2.9 1.8 1 0 0 1 1 1 1 Zinc knuckle GIY-YIG PF01541.24 GBG82231.1 - 6e-05 23.2 0.1 6e-05 23.2 0.1 2.5 2 1 0 2 2 2 1 GIY-YIG catalytic domain Rho_N PF07498.12 GBG82231.1 - 0.00065 19.6 1.8 0.0016 18.3 1.8 1.7 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Remorin_N PF03766.13 GBG82231.1 - 0.17 12.0 2.0 0.25 11.4 0.2 2.3 2 0 0 2 2 2 0 Remorin, N-terminal region RT_RNaseH_2 PF17919.1 GBG82233.1 - 2.1e-31 107.9 0.0 5.9e-31 106.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82233.1 - 1.4e-29 102.5 0.0 3.6e-29 101.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG82233.1 - 0.0052 17.0 0.4 0.066 13.5 0.0 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG82233.1 - 0.017 14.7 0.1 0.3 10.5 0.1 2.3 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) FTHFS PF01268.19 GBG82233.1 - 1.5 7.0 3.2 2.2 6.4 3.2 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Arc_PepC_II PF06847.11 GBG82233.1 - 6.2 7.4 5.8 1.5e+02 3.0 1.5 4.1 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II Rad21_Rec8_N PF04825.13 GBG82234.1 - 7.6e-25 87.2 0.1 9.2e-25 87.0 0.1 1.1 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8_N PF04825.13 GBG82235.1 - 1e-18 67.5 0.0 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein DUF538 PF04398.12 GBG82236.1 - 1.4e-29 102.7 0.0 1.8e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF538 DUF538 PF04398.12 GBG82237.1 - 0.0008 19.8 0.0 0.0012 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF538 PIEZO PF15917.5 GBG82238.1 - 5.5 6.4 8.2 9.3 5.6 8.2 1.3 1 0 0 1 1 1 0 Piezo RNA_polI_A34 PF08208.11 GBG82238.1 - 6.8 6.7 18.2 0.11 12.5 9.5 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 RT_RNaseH PF17917.1 GBG82239.1 - 4.2e-23 81.6 0.0 1.3e-22 80.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82239.1 - 7.8e-22 77.2 0.0 1.6e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG82239.1 - 6e-06 26.7 0.0 2.9e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82239.1 - 0.0007 20.2 0.0 0.002 18.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82239.1 - 0.017 14.9 0.5 0.03 14.1 0.5 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG82239.1 - 0.071 13.4 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RepB-RCR_reg PF10723.9 GBG82240.1 - 0.055 13.4 0.8 0.098 12.6 0.8 1.4 1 0 0 1 1 1 0 Replication regulatory protein RepB Rho_N PF07498.12 GBG82240.1 - 0.068 13.1 0.1 0.068 13.1 0.1 1.9 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain gag-asp_proteas PF13975.6 GBG82241.1 - 2.4e-06 28.0 0.0 6.7e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82241.1 - 0.00027 21.5 0.0 0.00085 19.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG82241.1 - 0.004 17.4 0.2 0.0093 16.2 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein RVP PF00077.20 GBG82241.1 - 0.0056 17.0 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82241.1 - 0.014 15.2 0.0 0.076 12.8 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease Presenilin PF01080.17 GBG82241.1 - 2.6 6.7 10.6 3.8 6.2 10.6 1.2 1 0 0 1 1 1 0 Presenilin gag-asp_proteas PF13975.6 GBG82242.1 - 5.8e-08 33.2 0.1 2.1e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82242.1 - 2.3e-06 28.1 0.3 7.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG82242.1 - 0.00022 21.0 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease AlaDh_PNT_C PF01262.21 GBG82242.1 - 0.034 13.4 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RVP_2 PF08284.11 GBG82242.1 - 0.052 13.3 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease ADC PF06314.11 GBG82243.1 - 3e-08 33.5 0.0 3.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) HSP70 PF00012.20 GBG82244.1 - 0.97 7.5 9.0 1.3 7.2 9.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Radial_spoke_3 PF06098.11 GBG82244.1 - 2 7.6 15.1 5.5 6.2 15.4 1.6 2 0 0 2 2 2 0 Radial spoke protein 3 DUF4236 PF14020.6 GBG82246.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) DUF515 PF04415.12 GBG82246.1 - 0.6 8.4 3.0 0.75 8.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Lyase_aromatic PF00221.19 GBG82247.1 - 3.4e-157 523.8 0.4 3.9e-157 523.6 0.4 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase cNMP_binding PF00027.29 GBG82248.1 - 1.7e-18 66.5 0.0 1.3e-10 41.2 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 GBG82248.1 - 4.5e-07 29.5 0.0 3.4e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain RVT_1 PF00078.27 GBG82250.1 - 9.2e-29 100.5 0.1 1.5e-28 99.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82250.1 - 2e-16 59.8 0.3 2e-16 59.8 0.3 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG82250.1 - 7.6e-11 42.2 0.0 2e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG82250.1 - 5.9e-06 26.1 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG82250.1 - 4.6e-05 23.9 0.0 0.00011 22.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82250.1 - 9e-05 23.0 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG82250.1 - 0.0002 21.2 0.0 0.0004 20.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG82250.1 - 0.016 15.4 0.1 0.041 14.1 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger SlyX PF04102.12 GBG82251.1 - 0.058 14.0 0.2 0.058 14.0 0.2 3.7 3 1 0 3 3 3 0 SlyX PFEMP PF03011.15 GBG82251.1 - 1.5 9.5 4.6 3.7 8.2 4.6 1.7 1 0 0 1 1 1 0 PFEMP DBL domain Myb_DNA-bind_4 PF13837.6 GBG82252.1 - 2.3e-08 34.3 1.9 2.3e-08 34.3 1.9 2.6 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82252.1 - 0.053 13.8 0.8 0.13 12.6 0.8 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Integrase_H2C2 PF17921.1 GBG82254.1 - 4.4e-16 58.7 0.0 9e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG82254.1 - 5.9e-11 42.3 0.1 8.8e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG82254.1 - 0.00015 22.0 0.1 0.00046 20.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain VAPB_antitox PF02697.14 GBG82254.1 - 0.067 14.0 0.1 0.16 12.7 0.1 1.6 1 0 0 1 1 1 0 Putative antitoxin zf-H2C2 PF09337.10 GBG82254.1 - 0.098 12.9 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger PP2C PF00481.21 GBG82255.1 - 4e-40 138.1 0.5 8e-40 137.1 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 GBG82255.1 - 0.0002 21.0 0.5 0.00099 18.8 0.5 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GBG82255.1 - 0.033 14.1 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) zf-CCHC PF00098.23 GBG82256.1 - 0.0028 17.7 1.2 0.0046 17.0 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG82256.1 - 0.065 13.1 5.2 0.12 12.3 5.2 1.4 1 0 0 1 1 1 0 Zinc knuckle APC_N_CC PF16689.5 GBG82256.1 - 0.27 11.3 0.1 0.27 11.3 0.1 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain RT_RNaseH PF17917.1 GBG82257.1 - 2.1e-17 63.3 0.0 4.7e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82257.1 - 3.8e-15 55.7 0.0 8.1e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82257.1 - 2.8e-13 49.7 0.2 9.7e-13 48.0 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82257.1 - 2.1e-11 44.1 0.0 6.1e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG82257.1 - 5e-08 33.4 0.0 2.1e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82257.1 - 8.4e-06 26.3 0.1 2.2e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82257.1 - 0.00015 21.5 0.1 0.00032 20.5 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Sporozoite_P67 PF05642.11 GBG82257.1 - 1.4 7.0 7.2 2.2 6.3 7.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ADIP PF11559.8 GBG82258.1 - 5e-36 124.1 8.9 5e-36 124.1 8.9 4.1 4 0 0 4 4 4 2 Afadin- and alpha -actinin-Binding HH_signal PF01085.18 GBG82258.1 - 0.15 11.7 2.6 0.37 10.4 0.2 2.4 1 1 1 2 2 2 0 Hedgehog amino-terminal signalling domain HSP90 PF00183.18 GBG82260.1 - 5.1e-215 715.3 28.1 5.1e-215 715.3 28.1 1.7 1 1 1 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 GBG82260.1 - 5.8e-13 49.3 0.3 1.1e-12 48.5 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GBG82260.1 - 6.5e-10 39.0 2.6 9.5e-10 38.4 0.2 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CobT PF06213.12 GBG82260.1 - 0.068 12.5 34.5 1.1 8.5 0.2 3.5 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 GBG82260.1 - 1.8 7.2 9.6 1.2 7.8 0.8 2.6 2 1 0 2 2 2 0 Presenilin Herpes_BLRF2 PF05812.12 GBG82261.1 - 0.00028 21.0 5.6 0.0013 18.9 0.5 3.4 2 1 0 3 3 3 1 Herpesvirus BLRF2 protein KASH_CCD PF14662.6 GBG82261.1 - 0.00053 19.9 2.0 0.00053 19.9 2.0 3.5 2 1 1 3 3 3 2 Coiled-coil region of CCDC155 or KASH CEP209_CC5 PF16574.5 GBG82261.1 - 0.016 15.4 4.8 0.016 15.4 4.8 3.6 4 0 0 4 4 4 0 Coiled-coil region of centrosome protein CE290 Shugoshin_N PF07558.11 GBG82261.1 - 0.49 10.3 6.9 0.18 11.7 0.7 3.3 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region peroxidase PF00141.23 GBG82262.1 - 8.6e-40 136.8 0.1 1.5e-39 136.0 0.1 1.3 1 0 0 1 1 1 1 Peroxidase CAP_N PF01213.19 GBG82262.1 - 2.9 7.3 4.9 4.8 6.6 4.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RT_RNaseH_2 PF17919.1 GBG82263.1 - 1.7e-24 85.7 0.0 3e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82263.1 - 3.9e-21 75.3 0.0 8.5e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG82264.1 - 3.4e-15 56.2 0.0 7.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG82264.1 - 0.00093 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG82265.1 - 9.5e-26 90.7 0.1 1.5e-25 90.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82265.1 - 1.5e-25 89.1 0.0 4e-25 87.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82265.1 - 2.3e-24 85.7 0.0 5.4e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82265.1 - 2e-18 66.2 0.2 6.9e-18 64.5 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG82265.1 - 1.2e-08 35.5 0.0 2.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82265.1 - 1.1e-07 32.3 0.0 2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG82265.1 - 5.1e-06 26.3 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82265.1 - 0.00022 21.0 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG82265.1 - 0.051 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF1499 PF07386.11 GBG82266.1 - 5.5e-19 68.9 0.0 6.4e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) DUF2285 PF10074.9 GBG82267.1 - 0.11 13.1 0.2 0.7 10.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) Dapper PF15268.6 GBG82269.1 - 0.2 10.5 16.5 0.25 10.1 16.5 1.1 1 0 0 1 1 1 0 Dapper TadF PF16964.5 GBG82269.1 - 1.5 8.5 7.8 0.5 10.1 4.8 1.7 2 0 0 2 2 2 0 Putative tight adherence pilin protein F DUF5401 PF17380.2 GBG82269.1 - 1.9 6.5 42.1 2.5 6.1 42.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Peptidase_S64 PF08192.11 GBG82269.1 - 4.1 5.8 8.5 4.7 5.6 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 RVT_1 PF00078.27 GBG82271.1 - 1e-29 103.7 0.0 2e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82271.1 - 1.1e-14 54.3 0.2 2.1e-14 53.4 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG82271.1 - 0.00013 22.1 0.2 0.00032 20.8 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger UPF0184 PF03670.13 GBG82272.1 - 0.048 14.1 0.1 0.099 13.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) ADIP PF11559.8 GBG82272.1 - 0.37 10.9 5.4 0.58 10.2 5.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CCDC53 PF10152.9 GBG82272.1 - 0.45 10.9 5.3 0.14 12.6 2.4 1.6 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex G_path_suppress PF15991.5 GBG82272.1 - 0.83 9.7 12.7 1.6 8.8 12.7 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor RT_RNaseH_2 PF17919.1 GBG82273.1 - 1.8e-25 88.8 0.0 6.6e-25 87.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82273.1 - 1e-23 83.6 0.0 2.5e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82273.1 - 9.2e-20 71.1 0.0 1.7e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_6 PF13912.6 GBG82273.1 - 5.4e-12 45.4 27.2 1.1e-05 25.3 0.4 6.7 7 0 0 7 7 7 4 C2H2-type zinc finger PHD PF00628.29 GBG82273.1 - 1.8e-09 37.4 5.3 1.8e-09 37.4 5.3 5.9 7 0 0 7 7 7 1 PHD-finger zf-C2H2 PF00096.26 GBG82273.1 - 3.1e-07 30.5 32.3 0.044 14.2 0.0 8.4 8 0 0 8 8 8 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GBG82273.1 - 2.2e-06 28.0 52.9 0.0094 16.7 0.1 9.8 11 0 0 11 11 11 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GBG82273.1 - 1.7e-05 24.9 12.3 0.25 11.7 0.1 7.0 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding Retrotrans_gag PF03732.17 GBG82273.1 - 0.12 12.6 0.4 0.88 9.9 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein zf-C2H2_2 PF12756.7 GBG82273.1 - 1.2 9.5 18.9 1.3 9.4 0.5 6.5 6 2 0 6 6 6 0 C2H2 type zinc-finger (2 copies) ING PF12998.7 GBG82274.1 - 7.4e-17 61.8 4.2 1.4e-16 60.9 4.2 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding FUSC PF04632.12 GBG82274.1 - 0.073 11.6 2.3 0.093 11.3 2.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family RVT_1 PF00078.27 GBG82280.1 - 2.7e-10 40.2 0.0 5.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG82280.1 - 4.2e-08 33.0 0.0 6.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82280.1 - 3.6e-07 30.7 0.0 6.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG82280.1 - 1.2e-06 28.3 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82280.1 - 4.2e-06 27.3 0.0 8.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG82281.1 - 2.5e-13 50.2 0.1 5.3e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82281.1 - 2.4e-08 33.9 0.0 6.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CENP-Q PF13094.6 GBG82283.1 - 0.0027 17.9 7.2 0.0045 17.2 7.2 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Peptidase_S49_N PF08496.10 GBG82283.1 - 0.6 10.2 7.0 0.93 9.5 7.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ER PF01133.17 GBG82284.1 - 2.2e-37 127.0 0.0 2.4e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Thioredoxin PF00085.20 GBG82285.1 - 5.2e-57 190.2 1.2 2e-28 98.4 0.0 4.3 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 GBG82285.1 - 1.7e-26 93.3 1.5 5.7e-16 59.0 1.0 3.2 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GBG82285.1 - 3.2e-11 43.2 0.0 1.9e-06 28.0 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 GBG82285.1 - 1.7e-09 37.5 0.0 0.00046 19.6 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GBG82285.1 - 7.1e-08 32.9 2.6 0.00064 20.2 0.0 4.2 3 2 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG82285.1 - 5.1e-05 23.5 0.2 2.5 8.5 0.0 4.8 3 2 1 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.17 GBG82285.1 - 0.0003 20.0 0.4 0.00062 18.9 0.4 1.6 1 0 0 1 1 1 1 Calsequestrin ERp29_N PF07912.13 GBG82285.1 - 0.00048 20.3 0.5 0.15 12.2 0.0 3.5 4 0 0 4 4 4 1 ERp29, N-terminal domain AhpC-TSA PF00578.21 GBG82285.1 - 0.0005 20.0 0.0 1.3 8.9 0.0 2.9 2 0 0 2 2 2 2 AhpC/TSA family GRP PF07172.11 GBG82285.1 - 0.007 17.0 0.1 0.007 17.0 0.1 2.2 2 0 0 2 2 2 1 Glycine rich protein family Thioredoxin_9 PF14595.6 GBG82285.1 - 0.027 14.2 2.0 4.2 7.2 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin Histone PF00125.24 GBG82286.1 - 1.9e-10 41.2 0.1 4.2e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pox_A21 PF05323.12 GBG82286.1 - 0.43 11.2 1.4 24 5.6 0.0 3.1 3 0 0 3 3 3 0 Poxvirus A21 Protein Thioredoxin PF00085.20 GBG82287.1 - 7.7e-27 93.3 0.2 5.3e-24 84.2 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 GBG82287.1 - 2.5e-22 79.7 2.6 1.7e-16 60.6 1.2 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 GBG82287.1 - 0.00011 21.7 0.0 0.00025 20.5 0.0 1.6 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family ERp29_N PF07912.13 GBG82287.1 - 0.0054 16.9 0.0 0.079 13.1 0.0 2.5 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_7 PF13899.6 GBG82287.1 - 0.014 15.5 0.0 0.38 11.0 0.0 2.9 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 GBG82287.1 - 0.046 14.2 1.0 0.78 10.2 0.0 3.1 2 1 1 3 3 3 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG82287.1 - 0.066 13.5 0.1 1.9 8.9 0.0 3.2 2 1 1 3 3 3 0 Thioredoxin-like Thioredoxin PF00085.20 GBG82288.1 - 1.8e-31 108.2 0.1 2.9e-19 68.9 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 GBG82288.1 - 3.5e-24 85.7 1.1 3.9e-15 56.2 0.5 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 GBG82288.1 - 3.6e-06 26.6 0.1 0.027 13.8 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GBG82288.1 - 0.00029 21.1 0.0 1.8 9.0 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 GBG82288.1 - 0.0028 17.6 0.0 0.077 12.9 0.0 2.6 2 1 0 2 2 2 1 AhpC/TSA family DUF4092 PF13322.6 GBG82288.1 - 0.005 16.7 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4092) Thioredoxin_7 PF13899.6 GBG82288.1 - 0.027 14.7 0.0 0.86 9.8 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin-like ERp29_N PF07912.13 GBG82288.1 - 0.083 13.0 0.2 25 5.1 0.0 3.3 3 0 0 3 3 3 0 ERp29, N-terminal domain DUF659 PF04937.15 GBG82292.1 - 2.1e-36 125.1 0.0 4.6e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG82292.1 - 0.0025 17.8 1.5 0.0042 17.1 0.7 1.8 2 0 0 2 2 2 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 GBG82292.1 - 0.011 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF1515 PF07439.11 GBG82292.1 - 0.079 13.0 0.3 0.44 10.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Antigen_Bd37 PF11641.8 GBG82292.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein zf-C2H2_4 PF13894.6 GBG82292.1 - 0.15 13.0 0.6 0.55 11.2 0.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Retrotrans_gag PF03732.17 GBG82293.1 - 0.02 15.2 0.8 0.075 13.3 0.2 2.3 2 1 0 2 2 2 0 Retrotransposon gag protein Methyltransf_11 PF08241.12 GBG82295.1 - 4.9e-11 43.1 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG82295.1 - 6.9e-08 33.1 0.0 1.5e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG82295.1 - 3.4e-06 27.0 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG82295.1 - 0.00025 20.5 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 GBG82295.1 - 0.00042 20.0 0.0 0.0011 18.6 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 GBG82295.1 - 0.0012 18.6 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG82295.1 - 0.0027 18.4 0.0 0.0063 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GBG82295.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase zf-RING_2 PF13639.6 GBG82297.1 - 5.7e-09 36.2 8.2 1.4e-08 34.9 4.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG82297.1 - 5.3e-08 32.6 10.0 1.6e-07 31.0 4.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG82297.1 - 1.5e-07 31.2 7.5 3e-07 30.2 3.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG82297.1 - 3e-07 30.3 5.2 8.6e-07 28.9 5.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG82297.1 - 2.3e-06 27.5 2.8 2.3e-06 27.5 2.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GBG82297.1 - 2.8e-06 27.1 1.7 2.8e-06 27.1 1.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG82297.1 - 0.0096 15.7 2.9 0.024 14.4 2.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 GBG82297.1 - 0.013 15.7 6.4 0.013 15.7 6.4 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GBG82297.1 - 0.019 14.8 0.9 0.058 13.3 0.9 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GBG82297.1 - 1 9.7 8.5 0.086 13.1 3.0 2.1 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 GBG82297.1 - 6.9 6.5 11.4 0.98 9.3 3.9 2.7 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 GBG82298.1 - 8.2e-08 32.5 5.7 8.2e-08 32.5 5.7 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG82298.1 - 9.3e-08 31.8 6.3 3.1e-07 30.1 6.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG82298.1 - 1.8e-06 27.9 7.0 4.7e-06 26.5 7.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GBG82298.1 - 2.8e-06 27.1 5.7 3.4e-06 26.8 2.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG82298.1 - 3.5e-06 26.8 5.7 3.5e-06 26.8 5.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG82298.1 - 4.4e-05 23.4 4.3 4.4e-05 23.4 4.3 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GBG82298.1 - 0.0074 16.4 7.2 0.0074 16.4 7.2 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ribbon_3 PF13248.6 GBG82298.1 - 0.028 13.8 0.3 0.028 13.8 0.3 3.2 2 1 1 3 3 3 0 zinc-ribbon domain zf-RING_10 PF16685.5 GBG82298.1 - 0.03 14.4 3.3 0.03 14.4 3.3 2.7 3 0 0 3 3 2 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 GBG82298.1 - 0.041 13.8 0.8 0.11 12.4 0.8 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RNA_POL_M_15KD PF02150.16 GBG82298.1 - 0.073 13.0 2.8 0.15 12.0 0.8 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-RING_11 PF17123.5 GBG82298.1 - 0.086 12.6 2.8 0.32 10.8 2.8 2.1 1 0 0 1 1 1 0 RING-like zinc finger Fez1 PF06818.15 GBG82298.1 - 0.092 13.2 17.2 0.13 12.7 17.2 1.1 1 0 0 1 1 1 0 Fez1 Prok-RING_4 PF14447.6 GBG82298.1 - 0.21 11.5 14.0 0.29 11.0 10.3 2.7 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 Phage_GPO PF05929.11 GBG82298.1 - 0.27 10.8 8.1 0.4 10.3 8.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DZR PF12773.7 GBG82298.1 - 0.36 10.9 8.5 0.13 12.3 1.7 2.9 3 0 0 3 3 2 0 Double zinc ribbon Acetone_carb_G PF08882.11 GBG82298.1 - 0.41 10.8 3.9 4.4 7.5 0.0 3.3 2 2 1 3 3 3 0 Acetone carboxylase gamma subunit zf-RING_4 PF14570.6 GBG82298.1 - 0.43 10.4 3.8 1.6 8.6 3.8 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Golgin_A5 PF09787.9 GBG82298.1 - 0.49 9.8 18.9 0.67 9.4 18.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 IBR PF01485.21 GBG82298.1 - 1.9 8.8 13.4 0.6 10.4 2.6 3.6 3 2 0 3 3 3 0 IBR domain, a half RING-finger domain RFC1 PF08519.12 GBG82298.1 - 2.9 8.1 8.9 4.7 7.4 8.9 1.3 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Cas_DxTHG PF09455.10 GBG82298.1 - 5.8 6.4 7.5 7.7 6.0 7.5 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family zf-rbx1 PF12678.7 GBG82298.1 - 8.1 6.8 11.6 4.2 7.7 7.4 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GBG82299.1 - 5.7e-09 36.2 7.0 2.1e-08 34.4 7.0 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG82299.1 - 8.8e-08 31.9 7.0 3.5e-07 29.9 7.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG82299.1 - 6.2e-06 26.0 4.3 6.2e-06 26.0 4.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG82299.1 - 8.8e-06 25.5 7.0 2.8e-05 23.9 7.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG82299.1 - 2.2e-05 24.4 8.0 5.4e-05 23.1 8.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG82299.1 - 9e-05 22.4 5.4 9e-05 22.4 5.4 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GBG82299.1 - 0.00076 19.6 7.5 0.0023 18.0 7.5 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prefoldin_2 PF01920.20 GBG82299.1 - 0.011 15.7 4.0 0.21 11.5 0.0 3.4 4 0 0 4 4 3 0 Prefoldin subunit Prok-RING_4 PF14447.6 GBG82299.1 - 0.014 15.3 9.5 0.52 10.2 9.9 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SlyX PF04102.12 GBG82299.1 - 0.014 16.0 2.4 0.014 16.0 2.4 3.4 3 0 0 3 3 3 0 SlyX ATG16 PF08614.11 GBG82299.1 - 0.036 14.3 3.4 0.62 10.3 0.1 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) zf-rbx1 PF12678.7 GBG82299.1 - 0.05 13.9 6.0 0.33 11.3 6.0 2.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain DivIC PF04977.15 GBG82299.1 - 0.094 12.5 0.4 0.094 12.5 0.4 2.6 2 0 0 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 GBG82299.1 - 0.17 12.2 8.6 3 8.2 0.2 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CAP_N PF01213.19 GBG82299.1 - 0.27 10.7 3.9 0.13 11.7 1.6 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Csm1_N PF18504.1 GBG82299.1 - 0.29 11.5 5.1 1.1 9.7 0.5 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain CRR7 PF12095.8 GBG82299.1 - 0.38 11.2 3.3 1.1 9.7 0.5 2.6 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Fez1 PF06818.15 GBG82299.1 - 0.4 11.1 6.7 0.29 11.6 4.8 1.6 2 0 0 2 2 2 0 Fez1 Prefoldin PF02996.17 GBG82299.1 - 0.4 10.6 4.7 0.76 9.7 0.2 2.8 3 0 0 3 3 3 0 Prefoldin subunit Blo-t-5 PF11642.8 GBG82299.1 - 0.65 10.0 5.1 0.55 10.2 0.1 2.3 2 0 0 2 2 2 0 Mite allergen Blo t 5 Retrotrans_gag PF03732.17 GBG82299.1 - 0.77 10.1 3.1 7.6 6.9 0.0 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein DUF5082 PF16888.5 GBG82299.1 - 0.83 9.9 8.1 1.7 8.9 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) SIKE PF05769.11 GBG82299.1 - 0.91 9.4 10.5 5.8 6.8 7.0 2.2 2 0 0 2 2 2 0 SIKE family CENP-H PF05837.12 GBG82299.1 - 2.1 8.8 6.1 16 6.0 1.3 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Baculo_PEP_C PF04513.12 GBG82299.1 - 2.5 8.1 4.6 10 6.2 0.2 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Auto_anti-p27 PF06677.12 GBG82299.1 - 3.3 8.0 0.0 3.3 8.0 0.0 4.5 4 1 1 5 5 4 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Med9 PF07544.13 GBG82299.1 - 7.6 6.7 12.3 1.1 9.4 0.3 3.6 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 RVT_1 PF00078.27 GBG82300.1 - 3.3e-29 102.0 0.1 6.1e-29 101.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82300.1 - 1.9e-16 59.9 0.0 6.4e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82300.1 - 5.9e-09 36.2 0.0 2.7e-08 34.0 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4187 PF13821.6 GBG82300.1 - 0.001 18.8 0.7 0.0031 17.3 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF4916 PF16262.5 GBG82300.1 - 0.081 12.4 0.6 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4916) Retrotrans_gag PF03732.17 GBG82300.1 - 0.22 11.8 0.1 0.22 11.8 0.1 3.6 4 0 0 4 4 4 0 Retrotransposon gag protein DUF2939 PF11159.8 GBG82300.1 - 8.2 6.9 9.6 1.5 9.3 0.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) DUF755 PF05501.11 GBG82301.1 - 0.14 12.4 4.8 0.18 12.1 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Syntaxin PF00804.25 GBG82302.1 - 1e-38 133.0 13.5 1.2e-36 126.3 3.9 2.6 3 0 0 3 3 3 2 Syntaxin SNARE PF05739.19 GBG82302.1 - 3.2e-20 71.8 3.4 3.2e-20 71.8 3.4 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 GBG82302.1 - 0.00012 22.4 1.8 0.00012 22.4 1.8 2.0 2 0 0 2 2 2 1 Syntaxin-like protein COG5 PF10392.9 GBG82302.1 - 0.01 16.0 2.8 3.2 7.9 0.0 3.5 3 1 0 3 3 3 0 Golgi transport complex subunit 5 Enkurin PF13864.6 GBG82302.1 - 0.02 15.3 3.6 1.1 9.8 0.2 2.5 1 1 1 2 2 2 0 Calmodulin-binding DUF2207 PF09972.9 GBG82302.1 - 0.024 13.4 5.7 0.077 11.7 5.7 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Prominin PF05478.11 GBG82302.1 - 0.025 12.5 6.3 0.063 11.2 6.3 1.5 1 1 0 1 1 1 0 Prominin Sec34 PF04136.15 GBG82302.1 - 0.037 13.9 1.0 0.037 13.9 1.0 2.5 2 1 1 3 3 3 0 Sec34-like family Nnf1 PF03980.14 GBG82302.1 - 0.045 14.1 2.0 0.082 13.3 0.8 2.0 1 1 0 1 1 1 0 Nnf1 FUSC PF04632.12 GBG82302.1 - 0.062 11.8 0.4 0.11 11.0 0.2 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Fusion_gly PF00523.18 GBG82302.1 - 0.085 11.1 4.4 0.071 11.4 2.1 1.8 2 0 0 2 2 2 0 Fusion glycoprotein F0 DUF2203 PF09969.9 GBG82302.1 - 0.12 13.1 6.1 0.3 11.8 0.8 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Laminin_II PF06009.12 GBG82302.1 - 0.16 12.0 6.4 0.16 12.0 0.5 2.6 3 0 0 3 3 3 0 Laminin Domain II DUF3675 PF12428.8 GBG82302.1 - 0.17 12.4 2.4 0.17 12.4 0.5 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF3675) UPF0242 PF06785.11 GBG82302.1 - 0.2 11.7 6.0 0.11 12.6 2.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AIP3 PF03915.13 GBG82302.1 - 0.21 10.7 6.4 0.05 12.7 2.5 1.7 2 0 0 2 2 2 0 Actin interacting protein 3 DUF3671 PF12420.8 GBG82302.1 - 0.21 11.6 3.6 0.15 12.2 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function Mod_r PF07200.13 GBG82302.1 - 0.31 11.1 5.1 0.13 12.3 1.4 2.2 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FapA PF03961.13 GBG82302.1 - 0.35 9.4 4.2 0.8 8.2 1.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Nup54 PF13874.6 GBG82302.1 - 0.95 9.6 10.5 11 6.1 5.5 3.6 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 CK2S PF15011.6 GBG82302.1 - 1 9.2 7.6 4.2 7.2 0.6 3.1 2 1 1 3 3 3 0 Casein Kinase 2 substrate DUF4208 PF13907.6 GBG82302.1 - 1.3 9.5 6.2 1 9.9 0.3 2.9 2 1 1 3 3 2 0 Domain of unknown function (DUF4208) TMF_TATA_bd PF12325.8 GBG82302.1 - 2.6 8.3 9.7 0.78 10.0 2.4 2.5 3 0 0 3 3 2 0 TATA element modulatory factor 1 TATA binding Phage_GPO PF05929.11 GBG82302.1 - 3.2 7.3 7.9 1.2 8.7 0.8 2.5 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase CLZ PF16526.5 GBG82302.1 - 3.5 8.1 8.7 30 5.0 1.5 3.5 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 GBG82302.1 - 4.8 7.7 12.5 16 6.0 0.0 4.0 2 1 1 3 3 3 0 Cell division protein ZapB Noelin-1 PF12308.8 GBG82302.1 - 6.1 6.9 8.1 6 6.9 0.9 3.4 3 1 1 4 4 4 0 Neurogenesis glycoprotein FlgN PF05130.12 GBG82302.1 - 6.1 7.3 8.3 2.5 8.6 1.6 2.9 2 1 2 4 4 4 0 FlgN protein DUF745 PF05335.13 GBG82302.1 - 6.2 6.5 10.5 6.3 6.5 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF745) GrpE PF01025.19 GBG82302.1 - 9.9 5.8 10.8 17 5.0 3.5 2.8 1 1 1 2 2 2 0 GrpE DUF4543 PF15076.6 GBG82304.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) DUF659 PF04937.15 GBG82305.1 - 2.5e-19 69.6 0.0 4.3e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) KTI12 PF08433.10 GBG82306.1 - 9.9e-10 38.3 0.2 9.9e-10 38.3 0.2 3.7 3 1 0 3 3 3 2 Chromatin associated protein KTI12 AAA_33 PF13671.6 GBG82306.1 - 0.023 14.8 0.0 0.023 14.8 0.0 4.5 4 1 1 5 5 5 0 AAA domain AAA_16 PF13191.6 GBG82306.1 - 0.13 12.7 3.7 0.48 10.8 0.0 3.6 4 0 0 4 4 4 0 AAA ATPase domain Myb_DNA-bind_4 PF13837.6 GBG82308.1 - 6.4e-07 29.7 1.0 1.3e-06 28.7 1.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG82311.1 - 3.1e-33 115.1 0.0 4.8e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Olduvai PF06758.13 GBG82311.1 - 0.04 14.2 0.7 0.15 12.4 0.7 2.0 1 0 0 1 1 1 0 Olduvai domain Asp_protease_2 PF13650.6 GBG82311.1 - 0.19 12.4 0.0 0.46 11.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease HAUS2 PF15003.6 GBG82311.1 - 0.45 10.2 2.0 2.7 7.7 0.1 2.5 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 2 AA_permease_2 PF13520.6 GBG82312.1 - 7.2e-19 67.9 11.0 9.4e-19 67.5 11.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GBG82312.1 - 2.5e-06 26.3 9.4 3.7e-06 25.8 9.4 1.1 1 0 0 1 1 1 1 Amino acid permease SEEEED PF14797.6 GBG82312.1 - 0.045 13.9 13.2 0.07 13.3 13.2 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex SpoIIIAH PF12685.7 GBG82312.1 - 1.6 8.5 6.4 2.3 8.0 6.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein FAM176 PF14851.6 GBG82312.1 - 3 7.5 5.4 5.7 6.6 5.4 1.4 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 GBG82312.1 - 3.7 8.0 8.7 8.7 6.8 8.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DTHCT PF08070.11 GBG82312.1 - 4.3 8.1 16.8 6.8 7.5 16.8 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region DHHC PF01529.20 GBG82314.1 - 1.3e-27 96.5 9.4 2.6e-27 95.6 9.4 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Cyt_bd_oxida_II PF02322.15 GBG82314.1 - 0.015 14.7 4.6 0.02 14.2 1.7 2.0 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II DUF3021 PF11457.8 GBG82314.1 - 0.75 10.1 10.8 0.088 13.1 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DUF3687 PF12459.8 GBG82314.1 - 3.6 7.2 4.6 8.5 6.0 4.6 1.6 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein rve PF00665.26 GBG82315.1 - 9.3e-15 54.9 0.0 2.7e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG82315.1 - 6.4e-14 51.8 1.5 8.6e-14 51.4 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain SlyX PF04102.12 GBG82315.1 - 0.0015 19.1 2.4 0.033 14.8 0.1 3.6 4 0 0 4 4 4 1 SlyX zf-H2C2 PF09337.10 GBG82315.1 - 0.028 14.6 0.1 0.068 13.4 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger pP_pnuc_2 PF18166.1 GBG82315.1 - 0.12 12.5 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease SMC_N PF02463.19 GBG82316.1 - 2.5e-25 89.2 0.0 8.1e-25 87.6 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RT_RNaseH_2 PF17919.1 GBG82316.1 - 4.2e-24 84.5 0.0 8.9e-22 77.0 0.0 2.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82316.1 - 9.8e-22 77.2 0.1 6.1e-20 71.5 0.0 3.5 3 0 0 3 3 2 1 RNase H-like domain found in reverse transcriptase AAA_23 PF13476.6 GBG82316.1 - 2.3e-16 60.9 0.1 2.3e-16 60.9 0.1 6.7 4 2 2 6 6 2 1 AAA domain RVT_1 PF00078.27 GBG82316.1 - 1.3e-09 37.9 0.4 3.8e-09 36.4 0.4 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_15 PF13175.6 GBG82316.1 - 6.4e-07 29.4 0.0 6.4e-07 29.4 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain SMC_hinge PF06470.13 GBG82316.1 - 1.1e-06 29.0 0.1 8.2e-06 26.1 0.0 2.7 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 GBG82316.1 - 0.00045 19.9 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HMMR_N PF15905.5 GBG82316.1 - 0.0012 18.4 16.3 0.0012 18.4 16.3 5.3 3 2 2 5 5 4 1 Hyaluronan mediated motility receptor N-terminal AAA_21 PF13304.6 GBG82316.1 - 0.0018 18.2 2.9 0.0064 16.3 0.0 3.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Retrotrans_gag PF03732.17 GBG82316.1 - 0.011 16.0 0.2 0.011 16.0 0.2 3.9 3 0 0 3 3 3 0 Retrotransposon gag protein Ploopntkinase3 PF18751.1 GBG82316.1 - 0.012 15.5 0.0 0.041 13.8 0.0 1.9 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 SbcCD_C PF13558.6 GBG82316.1 - 0.072 13.3 0.1 0.66 10.2 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 GBG82316.1 - 0.27 11.1 0.0 0.27 11.1 0.0 3.4 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 GBG82316.1 - 0.6 10.6 0.0 0.6 10.6 0.0 5.6 4 2 0 4 4 3 0 ABC transporter gag-asp_proteas PF13975.6 GBG82317.1 - 7.5e-08 32.8 0.0 2.2e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82317.1 - 8.3e-06 26.4 0.0 2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG82317.1 - 3.8e-05 23.3 0.0 7.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG82317.1 - 5.4e-05 23.0 0.4 0.00046 20.0 0.2 2.2 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG82317.1 - 0.0021 18.0 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG82317.1 - 0.0064 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease HlyD_D4 PF16572.5 GBG82317.1 - 0.014 15.2 0.4 0.048 13.5 0.4 2.0 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB RT_RNaseH PF17917.1 GBG82317.1 - 0.033 14.5 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase SQHop_cyclase_N PF13249.6 GBG82317.1 - 0.1 11.6 0.2 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Histone PF00125.24 GBG82318.1 - 3.5e-22 79.2 3.3 2.4e-21 76.5 0.0 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 RHH_7 PF16777.5 GBG82318.1 - 0.048 14.0 0.5 0.16 12.3 0.5 1.9 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG Histone PF00125.24 GBG82319.1 - 1.1e-12 48.4 0.4 2.3e-12 47.4 0.4 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_C48 PF02902.19 GBG82319.1 - 1.5e-05 25.0 0.1 2.6e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RRM_1 PF00076.22 GBG82320.1 - 1.1e-18 66.8 0.0 1.6e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GBG82321.1 - 9.7e-19 67.0 0.0 1.4e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.24 GBG82322.1 - 3e-18 66.4 0.1 3e-18 66.4 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 RRM_1 PF00076.22 GBG82323.1 - 7.9e-30 102.5 0.0 1.8e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG82323.1 - 3.6e-10 39.8 0.1 7.4e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GBG82323.1 - 1.8e-09 37.5 0.3 0.00095 19.1 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 GBG82323.1 - 0.12 12.2 0.0 0.93 9.4 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif CDC45 PF02724.14 GBG82326.1 - 2.1 6.6 6.8 2.6 6.2 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG82326.1 - 3.5 5.7 8.1 4 5.5 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG82327.1 - 6.1e-36 124.0 0.1 1e-35 123.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82327.1 - 9.9e-30 102.9 0.0 2.9e-29 101.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82327.1 - 1.9e-29 101.6 0.0 8e-29 99.6 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82327.1 - 5.4e-10 39.2 0.0 1.2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG82327.1 - 0.0052 16.6 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG82327.1 - 0.038 13.8 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Mrr_N PF14338.6 GBG82327.1 - 0.18 12.0 4.7 19 5.5 2.9 3.1 2 0 0 2 2 2 0 Mrr N-terminal domain EcpB_C PF18649.1 GBG82328.1 - 0.15 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 EcpB C-terminal domain N_Asn_amidohyd PF14736.6 GBG82329.1 - 6.1e-29 101.0 0.0 5e-21 75.0 0.0 2.3 2 0 0 2 2 2 2 Protein N-terminal asparagine amidohydrolase adh_short PF00106.25 GBG82330.1 - 2.4e-41 141.3 0.0 3.6e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG82330.1 - 1.5e-27 96.6 0.0 2.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG82330.1 - 1.8e-07 31.2 0.4 3.1e-07 30.5 0.4 1.3 1 0 0 1 1 1 1 KR domain DFP PF04127.15 GBG82330.1 - 0.13 12.1 0.4 0.29 10.9 0.4 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 GBG82330.1 - 0.2 11.5 0.1 0.41 10.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCI PF01399.27 GBG82331.1 - 5.7e-14 52.5 0.2 1.8e-13 50.9 0.1 1.9 2 0 0 2 2 2 1 PCI domain RVT_1 PF00078.27 GBG82331.1 - 4.1e-10 39.5 0.0 7.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPN7 PF10602.9 GBG82331.1 - 8.1e-09 35.4 0.9 1.9e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 Ribosomal_L1 PF00687.21 GBG82332.1 - 1.2e-45 155.7 0.0 1.7e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ADH_zinc_N PF00107.26 GBG82332.1 - 0.049 13.6 0.0 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Chromo PF00385.24 GBG82334.1 - 5.3e-11 42.3 0.1 9.1e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CreA PF05981.12 GBG82334.1 - 3.3e-05 23.9 0.2 5.5e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 CreA protein Retrotrans_gag PF03732.17 GBG82335.1 - 0.036 14.3 2.4 0.096 13.0 0.1 2.9 4 0 0 4 4 4 0 Retrotransposon gag protein Sulfatase_C PF14707.6 GBG82335.1 - 0.11 13.2 1.4 0.19 12.5 0.3 1.9 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DUF1515 PF07439.11 GBG82335.1 - 0.24 11.5 2.0 0.9 9.6 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) YabA PF06156.13 GBG82335.1 - 6 7.6 8.6 35 5.1 0.7 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Kinesin PF00225.23 GBG82336.1 - 1e-109 366.5 0.0 1.9e-109 365.6 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG82336.1 - 8.9e-48 162.0 0.0 1.6e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Spc7 PF08317.11 GBG82336.1 - 3.2e-05 23.0 7.9 3.2e-05 23.0 7.9 3.2 2 1 1 3 3 3 1 Spc7 kinetochore protein DUF812 PF05667.11 GBG82336.1 - 0.0034 16.3 5.9 0.0034 16.3 5.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Fez1 PF06818.15 GBG82336.1 - 0.0093 16.4 37.9 0.28 11.6 10.4 2.5 2 0 0 2 2 2 2 Fez1 Exonuc_VII_L PF02601.15 GBG82336.1 - 0.037 13.6 25.0 0.042 13.4 3.1 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Macoilin PF09726.9 GBG82336.1 - 0.13 10.8 22.4 0.019 13.5 12.2 2.2 2 0 0 2 2 2 0 Macoilin family Cast PF10174.9 GBG82336.1 - 0.13 10.5 30.1 0.6 8.3 12.3 2.2 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Fib_alpha PF08702.10 GBG82336.1 - 0.66 10.2 17.8 0.89 9.7 1.9 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 GBG82336.1 - 2.3 7.2 29.6 2.9 6.9 6.2 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C4H2 PF10146.9 GBG82336.1 - 5.7 7.2 18.4 0.93 9.8 1.1 3.4 3 0 0 3 3 3 0 Zinc finger-containing protein HMMR_N PF15905.5 GBG82336.1 - 7.6 5.9 35.5 1.5 8.2 9.3 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SKA1 PF07160.12 GBG82336.1 - 8.9 6.1 23.5 0.7 9.7 2.5 2.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Pkinase_Tyr PF07714.17 GBG82338.1 - 1.1e-38 133.0 0.0 5.3e-38 130.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82338.1 - 1.1e-36 126.5 0.0 1.6e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG82338.1 - 0.016 15.2 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Str_synth PF03088.16 GBG82339.1 - 1.7e-32 111.4 0.0 3.2e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 GBG82339.1 - 1.4e-12 47.8 0.0 1.7e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 GBG82339.1 - 0.00032 20.8 0.0 0.0029 17.8 0.0 2.1 1 1 1 2 2 2 1 Arylesterase Pkinase PF00069.25 GBG82340.1 - 4e-40 137.9 0.0 2.9e-22 79.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG82340.1 - 3.8e-36 124.7 0.0 1.5e-27 96.5 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GBG82340.1 - 6.4e-05 23.0 0.1 0.00025 21.0 0.4 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Lactonase PF10282.9 GBG82340.1 - 0.0063 15.8 0.1 1.7 7.8 0.0 2.6 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Pkinase_fungal PF17667.1 GBG82340.1 - 0.1 11.4 0.0 0.1 11.4 0.0 2.1 3 0 0 3 3 3 0 Fungal protein kinase Asp_protease_2 PF13650.6 GBG82342.1 - 0.0024 18.5 0.0 0.0055 17.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82342.1 - 0.008 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82342.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase PF00069.25 GBG82343.1 - 7.1e-16 58.4 0.0 1.7e-06 27.6 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GBG82343.1 - 1.8e-15 57.0 0.0 1.6e-08 34.1 0.0 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase Herpes_US9 PF06072.11 GBG82343.1 - 0.097 12.6 0.0 0.097 12.6 0.0 3.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 ubiquitin PF00240.23 GBG82344.1 - 0.2 11.4 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family zf-MIZ PF02891.20 GBG82345.1 - 9.1e-15 54.1 9.8 5.2e-14 51.7 5.7 2.5 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 GBG82345.1 - 0.0016 18.2 0.7 0.0044 16.8 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit HypA PF01155.19 GBG82345.1 - 0.17 11.9 2.7 0.97 9.5 0.4 2.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ISL3 PF14690.6 GBG82345.1 - 0.55 10.9 4.5 89 3.9 0.0 4.0 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DEK_C PF08766.11 GBG82347.1 - 0.027 14.4 0.7 0.044 13.7 0.1 1.7 2 0 0 2 2 2 0 DEK C terminal domain DDE_Tnp_4 PF13359.6 GBG82348.1 - 3.6e-31 108.0 0.0 6.4e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82348.1 - 7.5e-12 45.3 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG82348.1 - 0.094 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG82348.1 - 0.14 11.8 0.1 5.1 6.7 0.1 2.3 2 0 0 2 2 2 0 Transposase DDE domain Glyco_transf_34 PF05637.12 GBG82349.1 - 1e-10 41.8 0.1 4.2e-10 39.8 0.1 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_tranf_2_4 PF13704.6 GBG82349.1 - 0.15 12.6 0.5 0.35 11.4 0.5 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 RGS-like PF09128.11 GBG82350.1 - 0.4 10.4 3.2 0.97 9.1 3.2 1.6 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Catalase-rel PF06628.12 GBG82351.1 - 0.039 14.2 0.7 0.18 12.0 0.1 2.2 2 1 0 2 2 2 0 Catalase-related immune-responsive Myb_DNA-bind_4 PF13837.6 GBG82352.1 - 2.3e-07 31.1 3.8 2.3e-07 31.1 3.8 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG82352.1 - 0.0036 17.4 0.6 0.013 15.7 0.6 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82352.1 - 0.0037 17.6 1.2 0.03 14.6 0.4 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG82352.1 - 0.018 15.1 0.8 0.034 14.2 0.8 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG82353.1 - 9.4e-14 51.4 0.0 7.5e-13 48.4 0.0 2.3 2 1 1 3 3 3 1 DDE superfamily endonuclease API5 PF05918.11 GBG82354.1 - 6.8e-178 592.7 0.0 7.7e-178 592.5 0.0 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) Vps35 PF03635.17 GBG82354.1 - 0.0039 15.8 4.3 0.0055 15.3 4.3 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Microtub_bind PF13931.6 GBG82354.1 - 0.066 13.6 1.6 0.13 12.6 0.3 2.1 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding Fzo_mitofusin PF04799.13 GBG82354.1 - 3.3 7.2 5.2 0.76 9.3 0.5 2.1 2 0 0 2 2 2 0 fzo-like conserved region CheF-arch PF04283.12 GBG82355.1 - 0.0033 17.2 0.2 0.0073 16.1 0.2 1.5 1 0 0 1 1 1 1 Chemotaxis signal transduction system protein F from archaea Histone PF00125.24 GBG82356.1 - 2.9e-21 76.2 0.1 2.9e-21 76.2 0.1 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Choline_transpo PF04515.12 GBG82357.1 - 2e-92 309.9 33.2 2e-92 309.9 33.2 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter Myb_DNA-bind_4 PF13837.6 GBG82358.1 - 2.4e-06 27.8 0.7 4.8e-06 26.9 0.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82358.1 - 0.092 13.1 0.1 0.28 11.5 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Choline_transpo PF04515.12 GBG82360.1 - 6.8e-91 304.9 31.5 6.8e-91 304.9 31.5 2.3 3 0 0 3 3 3 1 Plasma-membrane choline transporter PHO4 PF01384.20 GBG82360.1 - 0.84 8.6 16.8 3.7 6.5 0.1 2.5 2 1 0 2 2 2 0 Phosphate transporter family DUF2294 PF10057.9 GBG82361.1 - 0.035 14.2 0.3 0.054 13.6 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) RRM_3 PF08777.11 GBG82362.1 - 7.4e-20 70.9 2.8 7.4e-20 70.9 2.8 3.5 3 0 0 3 3 3 1 RNA binding motif La PF05383.17 GBG82362.1 - 3.7e-19 68.5 0.0 1.4e-18 66.7 0.0 2.0 1 1 0 1 1 1 1 La domain RRM_1 PF00076.22 GBG82362.1 - 2.5e-14 52.8 4.1 6.1e-08 32.4 0.1 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GBG82362.1 - 0.04 13.9 0.6 0.24 11.4 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nop14 PF04147.12 GBG82363.1 - 5.1 5.2 23.9 6.2 4.9 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 GBG82364.1 - 1.2 8.1 6.4 1.4 7.9 6.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Sec62 PF03839.16 GBG82364.1 - 3.1 7.3 9.2 4.1 6.9 9.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S64 PF08192.11 GBG82364.1 - 5.7 5.3 5.2 5.6 5.3 5.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Zip PF02535.22 GBG82364.1 - 6.2 5.9 10.3 12 5.0 10.3 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter SRP-alpha_N PF04086.13 GBG82364.1 - 6.7 6.6 24.4 9.6 6.0 24.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pyr_redox_2 PF07992.14 GBG82365.1 - 3.1e-50 171.1 0.0 4.1e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG82365.1 - 0.014 16.0 0.3 0.057 14.0 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PMAIP1 PF15150.6 GBG82365.1 - 0.04 13.8 0.8 0.078 12.8 0.1 1.8 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced ABC_tran PF00005.27 GBG82366.1 - 5.1e-28 98.3 0.0 9e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GBG82366.1 - 4.9e-10 39.5 0.4 4.9e-10 39.5 0.4 2.4 1 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 GBG82366.1 - 0.00027 20.5 0.3 0.32 10.4 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MeaB PF03308.16 GBG82366.1 - 0.00099 18.2 0.3 0.0017 17.4 0.3 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3246 PF11596.8 GBG82366.1 - 0.0015 18.0 0.2 0.0028 17.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) DUF87 PF01935.17 GBG82366.1 - 0.0027 17.8 0.1 0.0051 16.9 0.1 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 GBG82366.1 - 0.0029 17.7 0.1 0.0065 16.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GBG82366.1 - 0.0062 16.9 0.1 0.018 15.4 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain DEAD PF00270.29 GBG82366.1 - 0.0066 16.2 1.9 0.088 12.6 1.8 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 GBG82366.1 - 0.0082 15.9 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GBG82366.1 - 0.015 15.1 0.0 0.066 13.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 GBG82366.1 - 0.029 14.1 0.0 0.07 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain FKBP_N_2 PF18023.1 GBG82366.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 BDBT FKBP like N-terminal Viral_helicase1 PF01443.18 GBG82366.1 - 0.045 13.5 0.1 0.54 10.0 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 GBG82366.1 - 0.048 13.0 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 GBG82366.1 - 0.052 13.8 0.3 0.3 11.4 0.3 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG82366.1 - 0.074 13.0 0.2 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain CENP-B_dimeris PF09026.10 GBG82366.1 - 0.076 13.4 2.5 0.15 12.4 2.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AAA_30 PF13604.6 GBG82366.1 - 0.086 12.6 0.1 0.38 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GBG82366.1 - 0.11 11.7 0.3 0.23 10.6 0.3 1.6 1 1 0 1 1 1 0 NB-ARC domain Cwf_Cwc_15 PF04889.12 GBG82366.1 - 0.88 9.3 5.3 0.13 12.0 1.2 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ceramidase PF05875.12 GBG82366.1 - 1.9 7.8 6.0 0.28 10.6 1.6 1.7 2 0 0 2 2 2 0 Ceramidase ABC_tran PF00005.27 GBG82367.1 - 4.3e-28 98.5 0.0 7.1e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GBG82367.1 - 8.8e-17 61.6 0.6 1.1e-16 61.3 0.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GBG82367.1 - 0.00019 20.9 0.3 0.26 10.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MeaB PF03308.16 GBG82367.1 - 0.00086 18.4 0.3 0.0014 17.6 0.3 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 GBG82367.1 - 0.0022 18.1 0.1 0.0044 17.2 0.1 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 GBG82367.1 - 0.0025 17.9 0.1 0.0055 16.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DEAD PF00270.29 GBG82367.1 - 0.0045 16.8 1.8 0.067 13.0 1.7 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 GBG82367.1 - 0.0066 16.8 0.3 0.014 15.7 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GBG82367.1 - 0.0072 16.1 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GBG82367.1 - 0.012 15.5 0.1 0.049 13.4 0.1 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 GBG82367.1 - 0.026 14.2 0.0 0.052 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 GBG82367.1 - 0.033 13.9 0.1 0.46 10.2 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FKBP_N_2 PF18023.1 GBG82367.1 - 0.034 14.2 0.0 0.091 12.9 0.0 1.7 2 0 0 2 2 1 0 BDBT FKBP like N-terminal Mg_chelatase PF01078.21 GBG82367.1 - 0.036 13.4 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 GBG82367.1 - 0.04 14.2 0.3 0.25 11.6 0.3 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG82367.1 - 0.053 13.4 0.2 0.75 9.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 GBG82367.1 - 0.062 13.0 0.1 0.32 10.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GBG82367.1 - 0.1 11.8 0.4 0.19 10.9 0.3 1.6 1 1 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 GBG82367.1 - 0.2 11.0 0.6 0.37 10.1 0.6 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RT_RNaseH_2 PF17919.1 GBG82368.1 - 1.7e-15 56.9 0.0 5.6e-15 55.2 0.0 1.9 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82368.1 - 9.2e-12 44.9 0.4 1.4e-11 44.3 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82368.1 - 2.3e-09 37.5 0.1 1.1e-05 25.6 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase zf-CCHC_4 PF14392.6 GBG82368.1 - 0.011 15.4 0.1 0.025 14.3 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG82368.1 - 0.13 12.4 4.1 0.22 11.7 4.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG82368.1 - 1.5 8.7 4.7 2 8.3 3.5 1.8 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG82369.1 - 2.7e-11 43.4 0.1 3.7e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG82369.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 1 1 0 1 1 1 0 Autophagy protein Apg17 gag-asp_proteas PF13975.6 GBG82370.1 - 1.8e-06 28.4 0.3 7.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82370.1 - 4.5e-05 24.0 0.3 0.00014 22.4 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG82370.1 - 0.0016 18.2 0.1 0.0039 17.0 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82370.1 - 0.028 14.2 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG82370.1 - 0.12 12.1 0.2 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease_2 PF13650.6 GBG82372.1 - 0.0027 18.3 0.1 0.0077 16.9 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82372.1 - 0.0067 16.2 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG82372.1 - 0.05 13.7 1.8 0.11 12.6 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Transthyretin PF00576.21 GBG82374.1 - 0.015 16.0 0.2 0.032 14.9 0.2 1.5 1 0 0 1 1 1 0 HIUase/Transthyretin family Lon_2 PF13337.6 GBG82374.1 - 0.047 12.2 2.3 0.075 11.6 2.3 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease Exonuc_VII_L PF02601.15 GBG82374.1 - 0.21 11.1 5.9 0.15 11.6 3.2 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit ALMT PF11744.8 GBG82374.1 - 1.8 7.3 5.8 4.5 6.0 5.3 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF659 PF04937.15 GBG82376.1 - 1e-13 51.4 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SWIRM-assoc_2 PF16496.5 GBG82376.1 - 1.3 7.8 4.3 2.5 6.9 4.3 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF3089 PF11288.8 GBG82378.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) RVT_1 PF00078.27 GBG82379.1 - 2e-35 122.3 0.0 3.2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2016 PF09436.10 GBG82379.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) Cys_Met_Meta_PP PF01053.20 GBG82380.1 - 7.7e-126 419.7 0.0 8.7e-126 419.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GBG82380.1 - 1.4e-06 27.5 0.1 2.5e-06 26.7 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GBG82380.1 - 8.5e-05 22.0 0.9 0.00026 20.4 0.9 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GBG82380.1 - 0.00011 21.6 0.2 0.00021 20.7 0.2 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 GBG82380.1 - 0.0012 17.5 0.0 0.0018 16.9 0.0 1.3 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GBG82380.1 - 0.024 13.5 0.1 0.052 12.4 0.1 1.5 1 1 1 2 2 2 0 Glycine cleavage system P-protein Tyrosinase PF00264.20 GBG82381.1 - 8.1e-31 108.0 9.1 2.8e-17 63.8 0.4 2.2 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG82381.1 - 3.3e-12 46.0 0.1 6.8e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain Tyrosinase PF00264.20 GBG82382.1 - 1.5e-28 100.6 12.0 1.5e-14 54.9 3.5 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG82382.1 - 6e-13 48.4 0.2 1.2e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain REV PF00424.18 GBG82383.1 - 0.096 12.7 5.1 0.12 12.4 0.8 2.5 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF3138 PF11336.8 GBG82383.1 - 0.51 8.9 4.3 0.93 8.0 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Exo_endo_phos PF03372.23 GBG82384.1 - 0.00032 20.3 0.0 0.0012 18.4 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG82384.1 - 0.0092 15.8 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase GvpG PF05120.12 GBG82384.1 - 0.04 13.9 0.2 0.099 12.7 0.2 1.6 1 0 0 1 1 1 0 Gas vesicle protein G NRN1 PF15056.6 GBG82384.1 - 0.05 13.7 0.6 0.27 11.3 0.1 2.3 2 0 0 2 2 2 0 Neuritin protein family DUF659 PF04937.15 GBG82385.1 - 3.7e-11 43.1 0.0 6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) TbpB_B_D PF01298.18 GBG82387.1 - 0.076 13.4 1.2 0.18 12.2 0.6 2.0 2 0 0 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Nop14 PF04147.12 GBG82387.1 - 0.16 10.2 13.1 0.21 9.8 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3391 PF11871.8 GBG82387.1 - 0.23 12.0 2.4 2.1 8.9 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) CDC45 PF02724.14 GBG82387.1 - 0.69 8.1 9.8 0.97 7.6 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG82387.1 - 0.88 8.9 13.4 1.4 8.3 13.4 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GBG82387.1 - 1.1 7.3 19.5 1.5 6.8 19.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 GBG82387.1 - 6.2 6.5 6.9 16 5.2 6.9 1.7 1 0 0 1 1 1 0 FAM176 family Helo_like_N PF17111.5 GBG82388.1 - 0.043 13.2 0.7 0.073 12.4 0.7 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins CCDC-167 PF15188.6 GBG82388.1 - 9.3 6.7 8.7 23 5.4 3.7 2.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 HATPase_c_3 PF13589.6 GBG82389.1 - 0.12 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tyrosinase PF00264.20 GBG82390.1 - 1e-30 107.7 7.9 7e-16 59.2 0.7 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG82390.1 - 3.7e-08 33.0 0.1 7.9e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain CTC1_2 PF15491.6 GBG82391.1 - 1.8e-15 57.0 1.2 0.00086 18.7 0.0 5.0 4 1 0 4 4 4 3 CST, telomere maintenance, complex subunit CTC1 POT1 PF02765.17 GBG82391.1 - 5.8e-11 42.4 0.0 3.2e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 TFIIA PF03153.13 GBG82391.1 - 0.00011 22.3 31.8 0.00011 22.3 31.8 8.1 5 2 1 6 6 6 2 Transcription factor IIA, alpha/beta subunit AAA_16 PF13191.6 GBG82392.1 - 0.00012 22.6 2.6 0.0063 16.9 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 GBG82392.1 - 0.0022 17.2 0.0 0.01 15.0 0.0 1.9 2 0 0 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 GBG82392.1 - 0.0028 17.6 0.0 0.0076 16.2 0.0 1.7 2 0 0 2 2 1 1 RsgA GTPase MMR_HSR1 PF01926.23 GBG82392.1 - 0.005 16.9 0.0 0.043 13.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 GBG82392.1 - 0.0097 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 GBG82392.1 - 0.016 14.4 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Septin PF00735.18 GBG82392.1 - 0.018 14.4 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Septin APG6_N PF17675.1 GBG82392.1 - 0.026 15.0 0.1 0.026 15.0 0.1 4.2 5 0 0 5 5 5 0 Apg6 coiled-coil region DUF4337 PF14235.6 GBG82392.1 - 0.028 14.5 0.3 0.028 14.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) TsaE PF02367.17 GBG82392.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GBG82392.1 - 0.061 13.0 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 GBG82392.1 - 0.068 13.7 0.1 0.94 10.0 0.0 2.7 2 0 0 2 2 2 0 ABC transporter IIGP PF05049.13 GBG82392.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 GBG82392.1 - 0.087 12.5 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG82392.1 - 0.099 12.6 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 GBG82392.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 GBG82392.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region E2F_CC-MB PF16421.5 GBG82392.1 - 1.9 8.9 8.2 4.3 7.8 0.5 3.2 3 0 0 3 3 2 0 E2F transcription factor CC-MB domain SbmA_BacA PF05992.12 GBG82393.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 SbmA/BacA-like family MMR_HSR1 PF01926.23 GBG82394.1 - 2.9e-06 27.4 0.0 1.3e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG82394.1 - 4.3e-05 23.5 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 GBG82394.1 - 8.9e-05 21.9 0.0 0.24 10.7 0.0 2.6 2 0 0 2 2 2 2 AIG1 family Septin PF00735.18 GBG82394.1 - 0.00047 19.5 0.0 0.00092 18.6 0.0 1.4 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 GBG82394.1 - 0.0006 19.4 0.3 0.0053 16.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 GBG82394.1 - 0.0015 18.0 0.3 0.19 11.1 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_29 PF13555.6 GBG82394.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.20 GBG82394.1 - 0.0024 17.1 0.0 0.0057 15.9 0.0 1.5 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 GBG82394.1 - 0.0044 17.4 0.0 0.022 15.1 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain IIGP PF05049.13 GBG82394.1 - 0.014 14.5 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.6 GBG82394.1 - 0.025 15.1 0.6 0.65 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GBG82394.1 - 0.045 12.9 0.0 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TniB PF05621.11 GBG82394.1 - 0.045 13.2 0.1 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 GBG82394.1 - 0.05 14.1 0.3 0.28 11.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 GBG82394.1 - 0.052 13.1 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 GBG82394.1 - 0.07 13.2 1.8 10 6.1 0.0 2.9 3 0 0 3 3 3 0 Dynamin family Sigma54_activat PF00158.26 GBG82394.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 GBG82394.1 - 0.08 12.0 0.6 0.16 11.0 0.0 1.7 2 0 0 2 2 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 GBG82394.1 - 0.1 13.0 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GBG82394.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 GBG82394.1 - 0.17 12.2 0.0 0.82 9.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain DUF4200 PF13863.6 GBG82394.1 - 2.6 8.5 10.1 0.47 10.9 6.1 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) DUF2570 PF10828.8 GBG82394.1 - 5.1 7.0 6.4 0.49 10.2 1.5 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2570) MMR_HSR1 PF01926.23 GBG82395.1 - 9.5e-07 28.9 0.0 6e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG82395.1 - 2.1e-06 27.7 0.0 1.3e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 GBG82395.1 - 1.2e-05 24.8 0.1 0.041 13.2 0.0 3.0 3 0 0 3 3 3 2 AIG1 family Septin PF00735.18 GBG82395.1 - 0.00052 19.4 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_29 PF13555.6 GBG82395.1 - 0.0016 18.1 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG82395.1 - 0.005 17.2 0.0 0.021 15.2 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 GBG82395.1 - 0.0065 15.8 0.1 0.27 10.6 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AbiEi_3 PF11459.8 GBG82395.1 - 0.0079 15.9 0.0 0.089 12.5 0.0 2.4 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Dynamin_N PF00350.23 GBG82395.1 - 0.01 15.9 0.1 6.5 6.8 0.0 3.1 3 0 0 3 3 3 0 Dynamin family IIGP PF05049.13 GBG82395.1 - 0.013 14.6 0.0 0.051 12.6 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) G-alpha PF00503.20 GBG82395.1 - 0.014 14.6 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit DUF4200 PF13863.6 GBG82395.1 - 0.014 15.8 1.8 0.042 14.3 1.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) GTP_EFTU PF00009.27 GBG82395.1 - 0.02 14.4 0.1 0.049 13.2 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 GBG82395.1 - 0.024 15.1 0.3 0.3 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GBG82395.1 - 0.026 14.8 0.0 0.076 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GBG82395.1 - 0.034 13.3 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 GBG82395.1 - 0.041 13.4 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GBG82395.1 - 0.05 14.1 0.1 0.19 12.3 0.0 2.0 2 0 0 2 2 1 0 ABC transporter TsaE PF02367.17 GBG82395.1 - 0.063 13.3 0.0 0.54 10.3 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 GBG82395.1 - 0.093 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 GBG82395.1 - 0.23 11.2 0.2 0.78 9.4 0.0 2.0 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 GBG82397.1 - 3e-06 27.3 0.0 8.3e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG82397.1 - 0.0001 22.3 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 GBG82397.1 - 0.0014 18.0 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 2 AIG1 family AAA_29 PF13555.6 GBG82397.1 - 0.0024 17.6 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 GBG82397.1 - 0.0053 16.1 0.0 0.012 14.9 0.0 1.5 1 1 0 1 1 1 1 Septin TsaE PF02367.17 GBG82397.1 - 0.0066 16.4 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GBG82397.1 - 0.0071 16.9 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 GBG82397.1 - 0.01 16.2 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 GBG82397.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 GBG82397.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 GBG82397.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 GBG82397.1 - 0.013 14.7 0.0 0.032 13.4 0.0 1.6 1 0 0 1 1 1 0 G-protein alpha subunit T2SSE PF00437.20 GBG82397.1 - 0.014 14.5 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 GBG82397.1 - 0.031 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain IIGP PF05049.13 GBG82397.1 - 0.043 12.9 0.0 0.095 11.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF815 PF05673.13 GBG82397.1 - 0.046 12.9 0.1 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 GBG82397.1 - 0.064 13.0 0.0 0.4 10.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 GBG82397.1 - 0.16 12.5 0.0 0.88 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GBG82397.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 GBG82397.1 - 0.2 11.0 0.1 0.49 9.7 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family XhlA PF10779.9 GBG82397.1 - 0.28 11.4 0.4 0.95 9.7 0.1 2.1 2 0 0 2 2 1 0 Haemolysin XhlA RT_RNaseH_2 PF17919.1 GBG82398.1 - 1.6e-14 53.7 0.0 3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82398.1 - 8.6e-11 41.8 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82398.1 - 3.4e-06 27.3 0.0 8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PG_binding_2 PF08823.11 GBG82398.1 - 0.12 12.7 0.4 22 5.4 0.1 3.5 2 1 2 4 4 4 0 Putative peptidoglycan binding domain Pkinase_Tyr PF07714.17 GBG82400.1 - 7e-33 114.0 0.0 6.9e-32 110.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82400.1 - 5.6e-26 91.5 0.0 2e-25 89.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain GIY-YIG PF01541.24 GBG82401.1 - 1.1e-05 25.6 2.3 0.0001 22.5 0.0 3.1 1 1 1 2 2 2 1 GIY-YIG catalytic domain Alanine_zipper PF11839.8 GBG82401.1 - 0.061 13.7 17.2 0.18 12.2 17.2 1.7 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Cwf_Cwc_15 PF04889.12 GBG82401.1 - 0.11 12.2 24.1 0.25 11.0 24.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF659 PF04937.15 GBG82402.1 - 1.4e-12 47.8 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) YL1 PF05764.13 GBG82402.1 - 0.0075 16.4 0.5 0.0075 16.4 0.5 3.1 3 0 0 3 3 3 1 YL1 nuclear protein SGL PF08450.12 GBG82403.1 - 0.0066 16.0 0.0 1.2 8.6 0.0 2.6 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region SGL PF08450.12 GBG82404.1 - 0.0029 17.2 0.0 0.18 11.4 0.0 2.3 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 GBG82404.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Myb_DNA-bind_4 PF13837.6 GBG82405.1 - 6.7e-09 36.0 1.2 5.8e-08 33.0 1.0 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG82405.1 - 0.0017 18.4 0.9 0.011 15.8 0.7 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82405.1 - 0.24 11.7 0.7 0.85 10.0 0.1 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Apt1 PF10351.9 GBG82406.1 - 4.9 5.9 11.6 5 5.9 11.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2052 PF09747.9 GBG82407.1 - 0.015 15.5 11.4 0.021 15.0 11.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF1168 PF06658.12 GBG82407.1 - 2.5 7.9 18.8 4.8 7.0 18.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Dimer_Tnp_hAT PF05699.14 GBG82408.1 - 2.2e-12 46.6 2.8 2.2e-12 46.6 2.8 2.9 3 1 0 3 3 3 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG82409.1 - 1e-49 166.7 0.0 2.3e-24 85.3 0.0 3.2 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82409.1 - 7.5e-46 154.8 0.0 5.4e-22 78.1 0.0 3.2 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82409.1 - 1.9e-24 86.4 0.5 5.6e-20 71.8 0.0 3.3 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) UCH PF00443.29 GBG82409.1 - 9.6e-13 48.2 0.7 1.8e-12 47.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RVP_2 PF08284.11 GBG82409.1 - 1.1e-06 28.5 0.0 2.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG82409.1 - 1.6e-06 28.6 0.0 1.9e-05 25.1 0.0 2.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82409.1 - 5e-06 27.1 0.0 1.4e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease UCH_1 PF13423.6 GBG82409.1 - 1.5e-05 24.8 4.5 5.1e-05 23.0 4.5 2.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Chromo PF00385.24 GBG82409.1 - 0.00056 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG82409.1 - 0.001 18.9 0.0 0.0031 17.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Integrin_b_cyt PF08725.11 GBG82409.1 - 0.02 14.5 0.3 6.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain TMEM247 PF15444.6 GBG82409.1 - 0.69 9.9 3.9 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 247 UCH PF00443.29 GBG82410.1 - 8.3e-06 25.5 0.2 8.3e-06 25.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Arm-DNA-bind_2 PF12167.8 GBG82410.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Arm DNA-binding domain WD40 PF00400.32 GBG82412.1 - 5.5e-10 39.7 0.7 0.63 11.0 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat FAM194 PF14977.6 GBG82412.1 - 0.25 10.6 1.0 0.65 9.3 0.1 2.1 2 0 0 2 2 2 0 FAM194 protein DUF812 PF05667.11 GBG82412.1 - 0.86 8.4 33.1 1.5 7.6 23.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Bcr-Abl_Oligo PF09036.10 GBG82412.1 - 2.5 8.2 6.8 0.26 11.3 0.6 2.4 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF743 PF05332.11 GBG82412.1 - 6.7 6.8 7.4 0.47 10.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF743) Glyco_tranf_2_3 PF13641.6 GBG82414.1 - 5e-26 92.0 0.0 7e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG82414.1 - 3.1e-22 79.5 1.8 3.1e-22 79.5 1.8 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG82414.1 - 5.5e-20 71.9 0.0 7.8e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 GBG82414.1 - 1.6e-19 70.0 11.3 1.6e-09 36.9 5.6 3.0 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 GBG82414.1 - 1.2e-15 57.4 0.0 1.8e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 GBG82414.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Asp_protease_2 PF13650.6 GBG82415.1 - 6.8e-07 29.9 0.0 4.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82415.1 - 4.3e-06 27.2 0.0 8.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG82415.1 - 0.0054 16.8 2.6 0.011 15.8 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG82415.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4604 PF15377.6 GBG82417.1 - 1.8 9.0 8.5 0.78 10.1 3.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Asp_protease_2 PF13650.6 GBG82418.1 - 1.9e-08 34.8 0.0 4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82418.1 - 2.8e-07 31.0 0.0 5.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG82418.1 - 1.3e-05 24.9 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82418.1 - 7.8e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG82418.1 - 0.0032 17.7 0.1 0.0097 16.2 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Paf1 PF03985.13 GBG82419.1 - 0.053 12.5 30.0 0.067 12.2 30.0 1.3 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 GBG82419.1 - 0.2 10.4 13.2 0.18 10.5 13.2 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GBG82419.1 - 0.2 11.4 18.6 0.23 11.2 18.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG82419.1 - 0.23 10.9 36.2 0.25 10.8 36.2 1.1 1 0 0 1 1 1 0 SDA1 DDHD PF02862.17 GBG82419.1 - 0.4 10.8 4.1 0.42 10.7 4.1 1.2 1 0 0 1 1 1 0 DDHD domain Dynamin_N PF00350.23 GBG82419.1 - 0.46 10.5 2.6 0.57 10.2 2.6 1.1 1 0 0 1 1 1 0 Dynamin family DUF913 PF06025.12 GBG82419.1 - 0.83 8.6 9.0 0.75 8.7 9.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 GBG82419.1 - 0.87 9.7 13.8 1.2 9.3 13.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4050 PF13259.6 GBG82419.1 - 1.2 9.5 9.2 1.7 8.9 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) AAA_11 PF13086.6 GBG82419.1 - 1.5 8.6 6.5 1.6 8.5 6.5 1.1 1 0 0 1 1 1 0 AAA domain Cwf_Cwc_15 PF04889.12 GBG82419.1 - 1.7 8.3 28.3 1.9 8.2 28.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_polI_A34 PF08208.11 GBG82419.1 - 3.3 7.8 27.7 4.1 7.4 27.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NPR3 PF03666.13 GBG82419.1 - 3.9 6.2 15.5 4.1 6.1 15.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 GBG82419.1 - 4 5.6 26.4 4.5 5.4 26.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 GBG82419.1 - 4.5 5.9 18.1 5.5 5.7 18.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PGA2 PF07543.12 GBG82419.1 - 4.7 7.2 27.9 8.1 6.4 27.9 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 SAPS PF04499.15 GBG82419.1 - 4.9 5.8 13.0 4.9 5.8 13.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 GBG82419.1 - 4.9 5.2 8.9 4.8 5.2 8.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.11 GBG82419.1 - 6 6.2 10.9 6.3 6.1 10.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SpoIIP PF07454.11 GBG82419.1 - 6.4 6.2 16.9 7.5 5.9 16.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nop14 PF04147.12 GBG82419.1 - 7.7 4.6 42.5 9 4.4 42.5 1.0 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 GBG82420.1 - 9.5e-19 67.8 0.0 1.8e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG82420.1 - 4e-18 65.6 0.0 6.9e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG82420.1 - 2.7e-05 24.8 1.0 2.4 9.1 0.1 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG82420.1 - 0.0002 21.6 0.1 0.0083 16.4 0.1 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG82420.1 - 0.013 14.2 0.4 0.079 11.6 0.2 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 KLRAQ PF10205.9 GBG82420.1 - 0.043 14.0 0.4 0.29 11.4 0.3 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DDE_Tnp_4 PF13359.6 GBG82421.1 - 4.1e-05 23.3 0.1 9e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.23 GBG82422.1 - 0.00048 20.1 0.8 0.00048 20.1 0.8 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG82422.1 - 0.063 13.1 0.4 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG82422.1 - 0.14 11.9 0.8 0.33 10.7 0.8 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF572 PF04502.13 GBG82422.1 - 0.29 10.7 18.2 0.37 10.3 18.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC27 PF09507.10 GBG82422.1 - 0.53 9.6 20.5 0.69 9.2 20.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ICA69 PF04629.14 GBG82422.1 - 3.4 7.9 8.0 4.6 7.5 8.0 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain Myb_DNA-bind_4 PF13837.6 GBG82423.1 - 1.2e-11 44.8 4.1 2.1e-11 44.0 4.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 GBG82424.1 - 0.031 14.6 0.2 0.031 14.6 0.2 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein Pkinase PF00069.25 GBG82425.1 - 6e-21 75.0 0.0 1.2e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG82425.1 - 1.6e-19 70.2 0.5 1.9e-18 66.7 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.32 GBG82425.1 - 5.7e-09 36.5 5.5 0.27 12.2 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat SlyX PF04102.12 GBG82425.1 - 0.11 13.1 2.3 0.32 11.6 2.3 1.9 1 0 0 1 1 1 0 SlyX MKRN1_C PF15815.5 GBG82425.1 - 0.13 12.7 0.7 0.45 10.9 0.7 2.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal OEP PF02321.18 GBG82425.1 - 2.9 7.6 5.7 4.9 6.9 5.7 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein WD40 PF00400.32 GBG82426.1 - 2.4e-07 31.3 3.7 0.02 15.7 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat EF-hand_6 PF13405.6 GBG82427.1 - 8.3e-12 44.0 0.6 0.15 12.1 0.1 5.4 6 0 0 6 6 6 3 EF-hand domain EF-hand_1 PF00036.32 GBG82427.1 - 1.1e-07 30.8 4.3 0.31 10.7 0.0 5.4 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 GBG82427.1 - 6.3e-07 29.8 1.6 1 9.9 0.1 4.8 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG82427.1 - 0.0049 16.3 0.4 3.6 7.3 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GBG82427.1 - 0.024 14.5 7.2 0.25 11.2 0.2 4.5 4 3 1 5 5 5 0 EF-hand domain pair CDC24 PF06395.11 GBG82427.1 - 0.089 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 CDC24 Calponin Myb_DNA-bind_4 PF13837.6 GBG82428.1 - 4.8e-08 33.3 3.1 1.3e-07 31.9 3.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82428.1 - 1.2 9.5 4.3 0.3 11.4 0.5 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG82429.1 - 9e-28 96.9 0.0 6.2e-27 94.2 0.0 2.2 2 1 1 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82429.1 - 2.4e-14 53.4 0.0 4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82429.1 - 0.018 14.7 0.1 0.88 9.2 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain SepSecS PF05889.13 GBG82430.1 - 0.025 13.3 3.4 0.03 13.0 3.4 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF3362 PF11842.8 GBG82430.1 - 0.071 13.4 5.7 0.085 13.2 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) PFK PF00365.20 GBG82430.1 - 0.42 9.9 2.3 0.54 9.5 2.3 1.2 1 0 0 1 1 1 0 Phosphofructokinase FapA PF03961.13 GBG82430.1 - 4.7 5.7 11.1 5.4 5.5 11.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CBFD_NFYB_HMF PF00808.23 GBG82431.1 - 2.1e-16 59.9 0.0 8.2e-16 58.0 0.0 1.9 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CBFD_NFYB_HMF PF00808.23 GBG82432.1 - 2.1e-16 59.9 0.0 8.2e-16 58.1 0.0 1.9 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RVT_1 PF00078.27 GBG82433.1 - 1e-30 106.9 0.1 2.1e-30 105.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82433.1 - 1.8e-19 69.6 0.3 4.7e-19 68.2 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG82433.1 - 1.2e-14 54.1 1.9 6e-14 51.9 0.0 3.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase GRIP PF01465.20 GBG82433.1 - 3.5e-11 42.8 0.0 1.6e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 GRIP domain RT_RNaseH PF17917.1 GBG82433.1 - 3.7e-05 23.9 0.0 0.00033 20.9 0.0 2.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG82433.1 - 0.00016 21.9 0.0 0.00043 20.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82433.1 - 0.0012 19.0 0.1 0.0034 17.6 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Rab_bind PF16704.5 GBG82433.1 - 4.3 7.4 21.3 0.021 14.8 5.6 4.5 5 0 0 5 5 5 0 Rab binding domain PPR_2 PF13041.6 GBG82434.1 - 4.1e-40 135.8 0.2 3.5e-15 55.9 0.0 7.8 6 1 2 8 8 8 7 PPR repeat family PPR PF01535.20 GBG82434.1 - 1.6e-29 100.1 16.0 9e-08 31.9 0.1 10.1 10 0 0 10 10 10 6 PPR repeat PPR_1 PF12854.7 GBG82434.1 - 4.9e-29 99.7 1.1 1.3e-07 31.2 0.1 7.3 7 0 0 7 7 7 5 PPR repeat PPR_3 PF13812.6 GBG82434.1 - 1.5e-23 82.6 0.1 2.6e-11 43.4 0.0 5.4 4 1 1 5 5 5 4 Pentatricopeptide repeat domain MMR_HSR1 PF01926.23 GBG82436.1 - 4e-07 30.1 0.0 8.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG82436.1 - 0.00012 22.1 0.4 0.00034 20.6 0.0 1.9 2 1 0 2 2 2 1 RsgA GTPase Neurochondrin PF05536.11 GBG82437.1 - 4.6e-57 193.7 0.0 6.4e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Neurochondrin Retrotrans_gag PF03732.17 GBG82438.1 - 4.6e-07 30.0 0.4 0.0019 18.4 0.0 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein CLZ PF16526.5 GBG82438.1 - 0.26 11.7 0.3 0.26 11.7 0.3 3.2 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AIF-MLS PF14962.6 GBG82438.1 - 8.4 6.3 8.8 1.9 8.4 5.3 1.6 2 0 0 2 2 2 0 Mitochondria Localisation Sequence zf-CCHC PF00098.23 GBG82439.1 - 4.9e-06 26.4 3.0 1.1e-05 25.2 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG82439.1 - 0.015 15.0 2.1 0.032 13.9 2.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG82439.1 - 0.18 11.6 0.9 0.38 10.5 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Zip PF02535.22 GBG82439.1 - 8.7 5.5 6.2 17 4.5 6.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DDE_Tnp_4 PF13359.6 GBG82440.1 - 3.5e-13 49.5 0.0 5.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82440.1 - 1.8e-06 27.7 0.0 3.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82440.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG82441.1 - 7.2e-11 42.3 0.7 7.2e-11 42.3 0.7 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82441.1 - 0.0046 17.2 0.1 0.016 15.5 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like RCR PF12273.8 GBG82441.1 - 4.2 8.0 6.0 10 6.8 3.4 2.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red zf-CCHC PF00098.23 GBG82442.1 - 6.8e-06 25.9 3.2 1.4e-05 24.9 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Integrase_H2C2 PF17921.1 GBG82442.1 - 2.6e-05 24.2 1.5 3.3e-05 23.9 0.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG82442.1 - 0.00055 19.5 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG82442.1 - 0.015 15.2 4.1 0.029 14.2 4.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2 PF09337.10 GBG82442.1 - 0.15 12.3 0.1 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger RSN1_7TM PF02714.15 GBG82443.1 - 2.5e-77 259.9 16.6 3.9e-77 259.3 16.6 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GBG82443.1 - 1.1e-42 146.3 0.4 1.7e-42 145.6 0.4 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GBG82443.1 - 3e-35 121.3 2.9 4.2e-35 120.8 0.4 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport RVT_1 PF00078.27 GBG82447.1 - 1.1e-26 93.8 0.1 2.1e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG82447.1 - 6.5e-07 29.8 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82447.1 - 2.2e-06 27.5 0.0 6.5e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG82447.1 - 3.4e-06 27.6 0.0 7.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82447.1 - 0.00012 21.9 0.0 0.00039 20.2 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease MatE PF01554.18 GBG82448.1 - 3e-57 192.8 30.0 1.8e-30 105.7 11.9 2.3 2 0 0 2 2 2 2 MatE MatE PF01554.18 GBG82450.1 - 7.8e-51 171.9 34.6 1.3e-26 93.2 10.3 2.5 3 0 0 3 3 3 2 MatE RT_RNaseH_2 PF17919.1 GBG82451.1 - 1.1e-23 83.2 0.0 1.9e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82451.1 - 1.2e-19 70.5 0.0 2.4e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82451.1 - 8.3e-18 64.2 0.4 1.9e-17 63.1 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG82451.1 - 1.2e-08 34.8 0.2 2e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG82451.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG82452.1 - 1.1e-32 112.0 0.0 2.6e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82452.1 - 2.1e-28 99.4 0.0 3.4e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82452.1 - 5.6e-28 97.3 0.0 1.1e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG82452.1 - 1.5e-06 28.7 0.0 2.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82452.1 - 1.4e-05 25.6 0.0 2.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82452.1 - 0.011 15.6 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82452.1 - 0.025 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG82452.1 - 0.033 14.0 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-CCHC PF00098.23 GBG82453.1 - 2.9e-05 23.9 4.3 5.2e-05 23.1 4.3 1.4 1 0 0 1 1 1 1 Zinc knuckle FeoA PF04023.14 GBG82453.1 - 0.015 15.5 0.0 0.072 13.4 0.0 2.0 2 0 0 2 2 2 0 FeoA domain Nas2_N PF18265.1 GBG82453.1 - 0.073 13.0 0.7 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Nas2 N_terminal domain POTRA PF07244.15 GBG82453.1 - 0.13 12.8 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Surface antigen variable number repeat OmpH PF03938.14 GBG82453.1 - 1.7 9.0 4.0 1.1 9.5 0.7 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-CCHC PF00098.23 GBG82454.1 - 4.5e-05 23.3 2.8 7.8e-05 22.6 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG82454.1 - 0.031 14.2 2.1 0.031 14.2 2.1 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG82454.1 - 0.15 11.8 2.3 0.33 10.7 2.3 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG82454.1 - 0.41 10.5 1.2 0.7 9.8 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Lsr2 PF11774.8 GBG82454.1 - 0.42 10.8 0.1 0.42 10.8 0.1 3.2 2 1 0 3 3 3 0 Lsr2 V_ATPase_I PF01496.19 GBG82454.1 - 1.8 6.3 6.6 2 6.2 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SUFU_C PF12470.8 GBG82454.1 - 3.6 7.6 7.4 5.7 6.9 7.4 1.5 1 1 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Tho2 PF11262.8 GBG82454.1 - 3.9 6.6 8.1 5.8 6.0 8.1 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 GBG82454.1 - 5.9 6.4 11.9 8.4 5.9 11.9 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4724 PF15852.5 GBG82454.1 - 9.9 6.7 6.5 57 4.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) RVT_1 PF00078.27 GBG82455.1 - 5.4e-27 94.8 0.0 9e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82455.1 - 8.3e-13 48.2 0.0 2.9e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG82455.1 - 3.9e-06 27.3 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82455.1 - 1.7e-05 25.4 0.0 9e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG82455.1 - 2.6e-05 24.0 0.0 7.6e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG82455.1 - 0.00089 19.5 1.9 0.13 12.6 0.0 3.6 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG82455.1 - 0.0023 18.2 0.0 0.0073 16.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG82455.1 - 0.013 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG82456.1 - 1.5e-30 105.1 0.0 1.7e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82456.1 - 2.5e-29 101.7 0.0 5.3e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82456.1 - 1e-27 97.1 0.0 1.7e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82456.1 - 1.3e-14 54.0 0.1 3e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82456.1 - 9.9e-13 48.3 0.0 4.3e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG82456.1 - 0.0049 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF4466 PF14725.6 GBG82457.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4466) SurA_N PF09312.11 GBG82457.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 SurA N-terminal domain DUF4466 PF14725.6 GBG82458.1 - 0.075 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4466) SurA_N PF09312.11 GBG82458.1 - 0.075 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 SurA N-terminal domain DDE_Tnp_4 PF13359.6 GBG82459.1 - 1.9e-22 79.6 0.0 4.9e-22 78.3 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82459.1 - 1.8e-13 50.6 0.0 3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82459.1 - 0.036 13.7 0.3 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG82459.1 - 0.058 13.8 0.5 0.2 12.0 0.2 2.1 2 0 0 2 2 2 0 Transposase DDE domain MatE PF01554.18 GBG82460.1 - 4.5e-54 182.5 31.0 4.1e-28 98.1 12.3 2.3 2 0 0 2 2 2 2 MatE Ring_hydroxyl_A PF00848.19 GBG82464.1 - 1.3e-05 25.3 0.5 0.13 12.2 0.1 2.4 2 0 0 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Helicase_C_4 PF13871.6 GBG82464.1 - 0.00071 19.3 0.1 1.4 8.5 0.0 2.2 2 0 0 2 2 2 2 C-terminal domain on Strawberry notch homologue Ehbp PF10622.9 GBG82464.1 - 0.0041 17.1 0.0 6.2 6.9 0.0 2.8 2 0 0 2 2 2 2 Energy-converting hydrogenase B subunit P (EhbP) Phage_tail_L PF05100.12 GBG82464.1 - 0.052 12.9 0.1 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Phage minor tail protein L Angiomotin_C PF12240.8 GBG82465.1 - 0.018 14.6 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 Angiomotin C terminal SlyX PF04102.12 GBG82465.1 - 4.8 7.9 6.8 0.41 11.3 0.7 2.4 2 1 0 2 2 2 0 SlyX DEK_C PF08766.11 GBG82468.1 - 0.0058 16.5 0.0 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 DEK C terminal domain FTR PF01913.18 GBG82468.1 - 0.18 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase MatE PF01554.18 GBG82470.1 - 2.6e-53 180.0 26.9 8.6e-27 93.8 9.3 2.3 2 0 0 2 2 2 2 MatE Use1 PF09753.9 GBG82471.1 - 0.014 15.2 8.6 0.019 14.7 8.6 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF4288 PF14119.6 GBG82471.1 - 0.14 12.6 1.9 0.32 11.4 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) DUF4404 PF14357.6 GBG82471.1 - 0.14 12.8 0.4 0.14 12.8 0.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) PIEZO PF15917.5 GBG82471.1 - 0.5 9.8 7.0 0.67 9.4 7.0 1.1 1 0 0 1 1 1 0 Piezo DUF3006 PF11213.8 GBG82471.1 - 1 9.7 3.7 11 6.3 3.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) DUF2937 PF11157.8 GBG82471.1 - 3.2 7.5 8.1 0.83 9.4 4.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) AIF-MLS PF14962.6 GBG82471.1 - 6.3 6.7 10.2 3 7.8 7.6 1.6 1 1 1 2 2 2 0 Mitochondria Localisation Sequence DUF3810 PF12725.7 GBG82471.1 - 9.5 5.5 6.7 1.3 8.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) RVT_1 PF00078.27 GBG82472.1 - 2.5e-24 86.0 0.2 4.1e-24 85.3 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG82472.1 - 0.081 13.2 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein rve PF00665.26 GBG82473.1 - 0.00022 21.4 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Peptidase_C39 PF03412.15 GBG82473.1 - 0.057 13.2 0.1 0.093 12.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase C39 family Integrase_H2C2 PF17921.1 GBG82473.1 - 0.068 13.3 0.3 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 Integrase zinc binding domain Kazal_1 PF00050.21 GBG82474.1 - 3.5e-13 49.3 13.6 8.7e-08 32.1 3.5 3.5 2 2 1 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 GBG82474.1 - 8.2e-09 35.5 24.0 2.4e-05 24.4 5.3 4.1 4 1 1 5 5 5 2 Kazal-type serine protease inhibitor domain Pkinase_Tyr PF07714.17 GBG82475.1 - 6.3e-43 146.9 0.0 9.8e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82475.1 - 3.8e-40 137.9 0.0 5.8e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RVP_2 PF08284.11 GBG82475.1 - 1.5e-08 34.5 0.0 4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease LRR_8 PF13855.6 GBG82475.1 - 6.9e-08 32.2 4.5 1.3e-06 28.0 0.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat Asp_protease_2 PF13650.6 GBG82475.1 - 2.3e-07 31.3 0.0 6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82475.1 - 2.6e-05 24.7 0.0 5.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease LRR_4 PF12799.7 GBG82475.1 - 0.00012 22.3 4.1 0.0062 16.9 0.2 2.8 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) Retrotrans_gag PF03732.17 GBG82475.1 - 0.0013 19.0 0.6 0.0079 16.4 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Pkinase_fungal PF17667.1 GBG82475.1 - 0.0031 16.4 0.7 0.012 14.4 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Asp_protease PF09668.10 GBG82475.1 - 0.0054 16.5 0.0 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease LRRNT_2 PF08263.12 GBG82475.1 - 0.02 15.2 0.0 0.067 13.5 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain FAM76 PF16046.5 GBG82475.1 - 0.17 11.2 5.2 0.35 10.2 5.2 1.4 1 0 0 1 1 1 0 FAM76 protein LRR_1 PF00560.33 GBG82475.1 - 0.22 12.2 5.2 1.2e+02 3.9 0.4 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Fer4_9 PF13187.6 GBG82477.1 - 0.0054 16.9 3.3 2.4 8.4 0.3 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 GBG82477.1 - 0.097 13.6 9.1 0.48 11.4 1.5 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain rve PF00665.26 GBG82478.1 - 9.1e-12 45.2 0.0 1.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG82478.1 - 2.8e-05 24.6 0.0 7.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82478.1 - 0.00029 21.4 0.0 0.00059 20.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG82478.1 - 0.00095 19.4 0.0 0.0027 18.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82478.1 - 0.0013 18.6 0.2 0.0044 16.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease rve_3 PF13683.6 GBG82478.1 - 0.0042 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG82479.1 - 2.1e-30 105.9 0.1 3.2e-30 105.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG82479.1 - 0.0023 18.5 0.0 0.0068 17.0 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG82480.1 - 2.2e-27 95.0 0.0 5.2e-27 93.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82480.1 - 1.5e-25 89.5 0.0 3.3e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82480.1 - 8.9e-19 67.4 2.1 2.6e-18 65.9 1.1 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG82480.1 - 1.1e-09 38.5 0.0 3.2e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG82480.1 - 3.7e-08 33.2 0.0 9.5e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG82480.1 - 0.0008 19.6 11.0 0.0051 17.0 0.1 4.4 4 0 0 4 4 4 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG82481.1 - 5.6e-23 81.2 0.0 1.2e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82481.1 - 1.3e-17 63.6 0.1 2.5e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG82481.1 - 4.3e-17 62.0 0.0 1.1e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG82481.1 - 1.2e-07 31.9 0.0 3.7e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG82481.1 - 0.001 18.9 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG82481.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG82482.1 - 1.4e-22 80.3 0.0 2.3e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82482.1 - 4.1e-21 74.9 0.1 9.4e-16 57.7 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82482.1 - 2.6e-16 59.5 1.2 8e-16 57.9 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG82482.1 - 3.5e-09 36.9 0.0 1.1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG82482.1 - 4e-09 36.7 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82482.1 - 3.1e-05 24.1 0.0 7.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG82482.1 - 0.0022 18.6 0.0 0.0059 17.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF5617 PF18493.1 GBG82483.1 - 6.8e-05 22.9 0.2 0.011 15.8 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF5617) DUF2203 PF09969.9 GBG82483.1 - 0.0069 17.1 1.3 0.022 15.5 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2203) HAUS6_N PF14661.6 GBG82483.1 - 0.029 14.0 4.4 0.098 12.2 4.4 2.0 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Jnk-SapK_ap_N PF09744.9 GBG82486.1 - 0.011 16.0 9.3 0.019 15.2 6.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 YqzH PF14164.6 GBG82486.1 - 0.033 14.2 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 YqzH-like protein PNPase_C PF12111.8 GBG82486.1 - 0.17 11.3 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal Csm1_N PF18504.1 GBG82486.1 - 0.34 11.3 5.9 1.2 9.6 4.8 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain RVT_1 PF00078.27 GBG82487.1 - 2.8e-28 99.0 0.1 4.9e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82487.1 - 6.8e-18 64.6 0.0 4e-15 55.7 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82487.1 - 4.8e-14 52.2 0.6 1.6e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG82487.1 - 4.3e-10 39.8 0.0 1.4e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG82487.1 - 9.5e-07 29.1 0.0 2.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG82487.1 - 2.2e-05 24.6 0.0 7.1e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG82488.1 - 4.4e-31 108.1 0.0 8.2e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82488.1 - 7.2e-30 103.0 0.0 1.2e-15 57.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82488.1 - 5.5e-29 100.5 0.0 1.2e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82488.1 - 2e-13 50.2 0.2 4.2e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG82488.1 - 0.0016 18.6 0.1 0.0038 17.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger GvpK PF05121.12 GBG82490.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 Gas vesicle protein K End3 PF12761.7 GBG82495.1 - 0.00054 20.2 12.3 0.00054 20.2 12.3 1.9 1 1 1 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 ZapB PF06005.12 GBG82495.1 - 0.0068 16.8 3.3 0.0068 16.8 3.3 3.2 1 1 1 2 2 2 1 Cell division protein ZapB PRKG1_interact PF15898.5 GBG82495.1 - 0.013 16.4 18.1 0.082 13.8 16.7 2.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 GBG82495.1 - 0.021 15.5 2.3 0.021 15.5 2.3 2.9 1 1 2 3 3 3 0 Initiation control protein YabA bZIP_1 PF00170.21 GBG82495.1 - 0.032 14.3 0.6 0.032 14.3 0.6 4.4 2 2 1 3 3 3 0 bZIP transcription factor DivIC PF04977.15 GBG82495.1 - 0.039 13.7 0.5 0.039 13.7 0.5 4.0 1 1 1 3 3 3 0 Septum formation initiator Csm1_N PF18504.1 GBG82495.1 - 0.32 11.4 20.0 1.5 9.2 0.5 4.8 1 1 3 4 4 4 0 Csm1 N-terminal domain DASH_Dam1 PF08653.10 GBG82495.1 - 0.32 10.8 0.9 8.1 6.3 0.1 3.0 2 1 0 2 2 2 0 DASH complex subunit Dam1 DUF2031 PF09592.10 GBG82495.1 - 0.62 9.6 10.1 0.74 9.3 9.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2031) FlaC_arch PF05377.11 GBG82495.1 - 0.64 10.5 11.3 0.82 10.1 0.3 4.4 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 GBG82495.1 - 0.74 9.8 8.8 2.7 8.0 5.0 2.7 1 1 1 2 2 2 0 FlxA-like protein DUF1664 PF07889.12 GBG82495.1 - 1.2 9.2 4.0 1.1 9.3 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Bap31_Bap29_C PF18035.1 GBG82495.1 - 1.5 8.9 18.9 32 4.6 0.1 4.7 2 2 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain SlyX PF04102.12 GBG82495.1 - 3.5 8.3 9.8 3.6 8.3 0.4 3.9 1 1 2 3 3 3 0 SlyX Med9 PF07544.13 GBG82495.1 - 3.9 7.6 13.6 0.16 12.1 1.3 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 APC_N_CC PF16689.5 GBG82495.1 - 4.4 7.5 20.6 1.5 9.0 1.4 4.9 3 2 1 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain MCU PF04678.13 GBG82495.1 - 7.1 6.7 10.2 4 7.5 4.6 2.3 1 1 1 2 2 2 0 Mitochondrial calcium uniporter DUF659 PF04937.15 GBG82497.1 - 2.2e-29 102.3 0.0 3.8e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pyridox_ox_2 PF12900.7 GBG82497.1 - 0.0086 16.1 0.9 0.022 14.7 0.9 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF5543 PF17697.1 GBG82497.1 - 0.088 13.1 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5543) GREB1 PF15782.5 GBG82497.1 - 3.6 4.6 13.5 4.8 4.2 13.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hydin_ADK PF17213.3 GBG82497.1 - 8.7 6.6 11.4 23 5.2 11.4 1.7 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Kazal_1 PF00050.21 GBG82498.1 - 0.00042 20.3 11.8 0.00075 19.5 11.8 1.5 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 GBG82498.1 - 0.028 14.5 15.2 0.09 12.9 15.2 1.9 1 1 0 1 1 1 0 Kazal-type serine protease inhibitor domain Integrase_H2C2 PF17921.1 GBG82499.1 - 2.5e-16 59.5 0.1 8.5e-16 57.8 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG82499.1 - 1.8e-12 47.5 0.0 5.1e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82499.1 - 1.3e-05 25.3 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG82499.1 - 0.082 12.7 0.1 0.25 11.1 0.1 1.8 1 0 0 1 1 1 0 Integrase core domain Integrase_H2C2 PF17921.1 GBG82500.1 - 1.2e-15 57.4 0.3 2.9e-15 56.1 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG82500.1 - 2.3e-12 47.2 0.0 5.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82500.1 - 3.9e-05 23.8 0.1 0.0001 22.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG82500.1 - 0.13 12.0 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG82501.1 - 2.8e-26 92.4 0.1 4.6e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82501.1 - 4.6e-21 74.7 0.0 7.5e-15 54.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG82501.1 - 2e-11 44.1 0.0 5.8e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG82501.1 - 1.1e-10 41.3 0.0 2.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG82501.1 - 4.6e-10 39.7 0.0 1.1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG82502.1 - 0.02 15.1 0.2 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Nop53 PF07767.11 GBG82502.1 - 0.43 9.9 31.5 0.9 8.9 31.5 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.12 GBG82502.1 - 3.4 7.0 32.4 5.6 6.3 32.4 1.3 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.10 GBG82502.1 - 7.3 6.9 17.7 19 5.5 17.7 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Asp_protease_2 PF13650.6 GBG82503.1 - 1.3e-05 25.7 0.0 3.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82503.1 - 1.4e-05 24.9 0.0 3.6e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG82503.1 - 0.00014 22.3 0.8 0.00044 20.8 0.1 2.3 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG82503.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG82503.1 - 0.095 12.5 0.0 0.28 11.0 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease Phage_lysozyme PF00959.19 GBG82503.1 - 0.15 12.5 0.4 1.4 9.4 0.0 2.6 2 1 0 2 2 2 0 Phage lysozyme Es2 PF09751.9 GBG82503.1 - 1.6 8.4 17.1 2.5 7.8 17.1 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 Cwf_Cwc_15 PF04889.12 GBG82504.1 - 0.0014 18.4 12.1 0.0017 18.1 12.1 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GBG82504.1 - 0.0088 15.4 15.6 0.01 15.2 15.6 1.0 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 GBG82504.1 - 1 7.6 14.3 1.2 7.4 14.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG82504.1 - 1.8 6.7 17.7 2.1 6.5 17.7 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG82504.1 - 2 7.8 17.4 2.2 7.6 17.4 1.1 1 0 0 1 1 1 0 SDA1 MSA-2c PF12238.8 GBG82504.1 - 3 7.8 7.1 4.3 7.3 7.1 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Nop53 PF07767.11 GBG82504.1 - 4.2 6.6 17.6 5.2 6.3 17.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 GBG82504.1 - 5.1 7.0 25.4 6.7 6.7 25.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) BUD22 PF09073.10 GBG82505.1 - 0.19 11.0 21.6 0.27 10.5 21.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG82505.1 - 0.48 8.6 18.0 0.6 8.3 18.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG82505.1 - 0.85 9.0 20.3 1.1 8.6 20.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG82505.1 - 2.9 6.1 16.0 3.9 5.6 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 GBG82505.1 - 5.2 6.1 10.2 7.3 5.6 10.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TRAP_alpha PF03896.16 GBG82505.1 - 6.6 5.8 8.7 10 5.3 8.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Na_Ca_ex PF01699.24 GBG82507.1 - 2.4e-13 50.3 22.1 2.8e-11 43.6 16.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_7 PF13499.6 GBG82507.1 - 8.4e-09 35.8 2.2 4.5e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG82507.1 - 9.8e-09 34.2 0.0 0.00067 19.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GBG82507.1 - 1.3e-07 31.0 0.0 0.0083 16.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GBG82507.1 - 3.1e-05 23.2 0.1 0.025 14.1 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GBG82507.1 - 0.00017 21.4 0.2 0.46 10.4 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair RhodobacterPufX PF11511.8 GBG82507.1 - 0.01 15.4 0.3 0.043 13.4 0.3 2.1 1 0 0 1 1 1 0 Intrinsic membrane protein PufX TMEMspv1-c74-12 PF11044.8 GBG82507.1 - 0.038 14.0 2.4 0.64 10.0 0.2 3.0 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein EF-hand_10 PF14788.6 GBG82507.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 EF hand Porphobil_deam PF01379.20 GBG82508.1 - 0.028 13.9 0.0 0.059 12.9 0.0 1.5 1 1 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain DUF507 PF04368.13 GBG82508.1 - 0.032 14.2 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF507) Pkinase PF00069.25 GBG82509.1 - 8.2e-65 218.8 0.0 9.7e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG82509.1 - 1.4e-36 126.2 0.0 1.9e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 GBG82509.1 - 0.0002 21.0 0.2 0.0003 20.5 0.2 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 GBG82509.1 - 0.0012 17.7 0.0 0.0016 17.3 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GBG82509.1 - 0.0049 16.2 0.1 0.25 10.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GBG82509.1 - 0.024 14.6 0.4 0.51 10.2 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF575 PF04746.12 GBG82510.1 - 0.83 9.9 0.0 0.83 9.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF575) CENP-F_leu_zip PF10473.9 GBG82511.1 - 0.00021 21.3 9.5 0.00021 21.3 9.5 4.7 2 2 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 GBG82511.1 - 0.0031 17.6 14.6 0.0031 17.6 14.6 4.2 2 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding TRAF_BIRC3_bd PF16673.5 GBG82511.1 - 0.0097 15.7 12.2 0.029 14.1 0.9 3.8 4 0 0 4 4 4 2 TNF receptor-associated factor BIRC3 binding domain DUF4833 PF16117.5 GBG82511.1 - 0.017 15.1 0.5 0.035 14.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4833) DUF1192 PF06698.11 GBG82511.1 - 0.026 14.6 4.8 9.1 6.4 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) SlyX PF04102.12 GBG82511.1 - 0.5 11.0 23.0 7.4 7.3 1.5 5.7 3 2 2 5 5 5 0 SlyX ATG16 PF08614.11 GBG82511.1 - 1 9.5 48.3 3 8.0 7.7 4.0 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 GBG82511.1 - 5.1 5.6 28.1 0.089 11.4 20.7 1.6 2 0 0 2 2 2 0 AAA domain LPP PF04728.13 GBG82511.1 - 6.8 7.2 8.0 54 4.3 0.1 4.0 3 1 1 4 4 4 0 Lipoprotein leucine-zipper RT_RNaseH_2 PF17919.1 GBG82512.1 - 7.7e-26 90.1 0.0 2.1e-25 88.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82512.1 - 4.1e-24 84.9 0.2 2.3e-23 82.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82512.1 - 1e-16 60.8 2.0 2.2e-16 59.7 0.4 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG82512.1 - 9.2e-09 35.5 0.0 3.6e-08 33.6 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG82512.1 - 0.00079 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG82512.1 - 0.0015 18.8 0.1 0.0015 18.8 0.1 4.5 4 1 0 4 4 4 1 Retrotransposon gag protein Chromo PF00385.24 GBG82512.1 - 0.011 15.6 0.1 0.028 14.3 0.1 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG82512.1 - 0.11 12.7 0.9 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger CLZ PF16526.5 GBG82512.1 - 1.2 9.5 7.7 6.6 7.2 2.4 3.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_Gp23 PF10669.9 GBG82512.1 - 7.3 7.0 8.6 2.1 8.7 1.3 2.7 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) HR_lesion PF05514.11 GBG82514.1 - 2.7e-41 141.0 3.0 3.1e-41 140.8 3.0 1.0 1 0 0 1 1 1 1 HR-like lesion-inducing SURF4 PF02077.15 GBG82514.1 - 0.0032 17.1 0.1 0.0039 16.8 0.1 1.1 1 0 0 1 1 1 1 SURF4 family Herpes_UL73 PF03554.13 GBG82514.1 - 0.51 10.4 2.2 0.31 11.1 0.3 1.6 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein DoxX PF07681.12 GBG82514.1 - 1.7 9.3 9.4 0.38 11.4 6.0 1.7 2 1 0 2 2 2 0 DoxX BCDHK_Adom3 PF10436.9 GBG82515.1 - 0.19 11.5 0.0 4.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase RVT_1 PF00078.27 GBG82517.1 - 7.4e-32 110.7 0.1 1.2e-31 110.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG82517.1 - 1.5e-12 47.2 0.0 3.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG82517.1 - 2e-08 34.4 0.1 1e-07 32.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG82517.1 - 0.094 13.4 0.0 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease tRNA-synt_2c PF01411.19 GBG82518.1 - 2.5e-215 716.2 0.0 3.1e-215 715.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GBG82518.1 - 8.6e-17 61.0 0.0 1.9e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 GBG82518.1 - 2.2e-12 47.6 7.2 5.7e-12 46.2 7.2 1.7 1 0 0 1 1 1 1 DHHA1 domain tRNA-synt_His PF13393.6 GBG82518.1 - 0.046 13.0 0.7 0.13 11.5 0.9 1.6 2 0 0 2 2 2 0 Histidyl-tRNA synthetase zf-ZPR1 PF03367.13 GBG82519.1 - 3.2e-108 358.6 0.0 7.9e-53 178.6 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DiS_P_DiS PF06750.13 GBG82519.1 - 0.26 11.4 3.3 17 5.6 1.7 2.6 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-ribbon_3 PF13248.6 GBG82519.1 - 0.29 10.6 2.5 4.7 6.8 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.18 GBG82519.1 - 0.88 8.9 2.7 17 4.9 0.1 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DDE_Tnp_4 PF13359.6 GBG82520.1 - 5.6e-12 45.6 0.0 2.7e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82520.1 - 0.0029 17.3 0.0 0.0038 16.9 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82520.1 - 0.018 14.7 0.1 0.13 11.8 0.2 2.0 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG82520.1 - 0.073 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Rhodanese PF00581.20 GBG82521.1 - 2.3e-10 41.0 0.0 4.9e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain RVT_1 PF00078.27 GBG82524.1 - 4e-29 101.7 0.0 6e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG82524.1 - 0.0042 17.7 0.0 0.0084 16.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Presenilin PF01080.17 GBG82525.1 - 7.6 5.2 5.1 9.6 4.8 5.1 1.1 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG82526.1 - 1.3e-29 103.3 0.0 2.6e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82526.1 - 3.9e-20 72.1 0.0 1e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82526.1 - 3.3e-16 59.1 0.2 1.5e-15 57.0 0.0 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG82526.1 - 2.1e-10 40.5 0.0 7.5e-10 38.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG82526.1 - 2.2e-10 40.7 0.0 6e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82526.1 - 2.8e-05 24.2 0.0 7.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG82527.1 - 4.9e-36 124.3 0.0 2.2e-35 122.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG82527.1 - 1e-08 35.7 4.2 3.3e-08 34.1 4.2 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 GBG82529.1 - 1e-08 35.0 0.0 1.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-HC2 PF13490.6 GBG82529.1 - 0.13 12.6 0.7 1.6 9.1 0.2 3.1 3 0 0 3 3 3 0 Putative zinc-finger Malic_M PF03949.15 GBG82530.1 - 1.7e-98 329.0 0.5 2.2e-98 328.6 0.5 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GBG82530.1 - 4.7e-71 238.4 0.0 7.9e-71 237.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RVT_1 PF00078.27 GBG82531.1 - 4.2e-37 127.8 0.0 6.2e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GFO_IDH_MocA PF01408.22 GBG82532.1 - 1.8e-21 77.2 0.0 2.8e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Glyco_transf_34 PF05637.12 GBG82533.1 - 3.9e-35 121.7 0.0 4.8e-34 118.1 0.0 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF659 PF04937.15 GBG82534.1 - 1.3e-31 109.6 0.2 2.5e-31 108.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG82534.1 - 0.008 15.9 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Asp_protease_2 PF13650.6 GBG82535.1 - 3.6e-08 34.0 0.0 1.2e-07 32.3 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG82535.1 - 1.2e-07 31.5 0.0 3.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG82535.1 - 3.1e-06 27.7 0.0 1.6e-05 25.4 0.0 2.2 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82535.1 - 0.0079 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG82536.1 - 2.7e-24 85.1 0.0 4.5e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82536.1 - 3.3e-24 85.2 0.0 5.9e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82536.1 - 1.7e-18 66.5 0.1 4.3e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG82536.1 - 2.3e-10 40.4 0.1 4e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG82536.1 - 2.8e-09 37.2 0.0 9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82536.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Nif11 PF07862.11 GBG82536.1 - 0.15 12.4 0.0 0.75 10.1 0.0 2.2 2 0 0 2 2 2 0 Nif11 domain DUF659 PF04937.15 GBG82539.1 - 2.3e-08 34.0 0.0 3.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG82539.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RT_RNaseH PF17917.1 GBG82540.1 - 4e-22 78.5 0.0 9.5e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82540.1 - 5.4e-20 71.3 0.0 9.7e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82540.1 - 3.7e-09 36.4 0.0 6.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG82540.1 - 7.1e-08 32.9 0.1 1.8e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82540.1 - 1.8e-07 31.7 0.1 4.4e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82540.1 - 2.8e-05 23.9 0.3 5.1e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82540.1 - 0.0026 17.5 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Sigma70_ner PF04546.13 GBG82541.1 - 0.059 13.2 2.0 0.15 12.0 2.0 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 GBG82541.1 - 1.3 7.1 5.7 1.8 6.7 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG82541.1 - 3.2 5.9 5.1 4.8 5.4 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 GBG82542.1 - 1.7e-45 155.5 0.3 3.5e-45 154.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG82542.1 - 2.9e-44 151.3 0.0 1.3e-43 149.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG82542.1 - 0.018 15.0 0.1 0.018 15.0 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family SOBP PF15279.6 GBG82542.1 - 8.2 6.9 21.9 8.9 6.8 6.8 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein RT_RNaseH_2 PF17919.1 GBG82543.1 - 1.4e-32 111.7 0.1 6.7e-32 109.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82543.1 - 3.5e-29 101.2 0.2 6.7e-29 100.3 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82543.1 - 1.1e-26 93.8 0.1 1.9e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82543.1 - 6.4e-18 64.6 0.4 2e-17 63.1 0.4 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82543.1 - 3.3e-10 40.2 0.0 6.9e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG82543.1 - 1.1e-06 29.1 0.0 2.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82543.1 - 8.1e-05 23.2 0.0 0.00019 22.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82543.1 - 0.019 14.7 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG82543.1 - 0.027 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RAP1 PF07218.11 GBG82544.1 - 0.1 10.9 1.3 0.16 10.3 1.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Miga PF10265.9 GBG82544.1 - 0.82 8.6 3.2 0.98 8.3 3.2 1.2 1 0 0 1 1 1 0 Mitoguardin Period_C PF12114.8 GBG82544.1 - 8.7 5.9 13.0 9.2 5.8 8.1 2.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region TssD PF17642.1 GBG82548.1 - 0.0093 15.8 0.5 1.7 8.5 0.0 2.8 3 0 0 3 3 3 2 Hemolysin coregulated protein Hcp (TssD) DUF507 PF04368.13 GBG82548.1 - 0.024 14.6 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF507) DUF1110 PF06533.12 GBG82549.1 - 0.017 15.1 0.1 0.038 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) SCAN PF02023.17 GBG82549.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 SCAN domain RT_RNaseH_2 PF17919.1 GBG82550.1 - 1.4e-33 114.9 0.0 3.1e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82550.1 - 1.2e-28 99.5 0.2 4.8e-28 97.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82550.1 - 9.1e-25 87.5 0.1 1.7e-24 86.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82550.1 - 2.1e-17 63.0 0.6 7.2e-17 61.2 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG82550.1 - 3.1e-12 46.7 0.1 3e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG82550.1 - 0.015 15.6 1.1 0.16 12.3 0.0 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein Snapin_Pallidin PF14712.6 GBG82550.1 - 0.1 13.1 1.4 1.5 9.3 0.2 3.1 2 0 0 2 2 2 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 GBG82550.1 - 2.3 7.7 5.6 5.8 6.4 5.6 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit EzrA PF06160.12 GBG82550.1 - 3.4 5.7 6.5 6.2 4.9 6.5 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Phage_GPO PF05929.11 GBG82550.1 - 6.9 6.2 5.7 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG82551.1 - 3.5e-12 46.2 0.0 8.8e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG82551.1 - 0.006 16.8 1.0 0.059 13.7 0.0 3.1 4 0 0 4 4 4 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG82551.1 - 0.19 11.1 13.1 1.1 8.5 12.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HAUS6_N PF14661.6 GBG82551.1 - 3.2 7.3 6.8 8.6 5.9 6.8 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CSRNP_N PF16019.5 GBG82553.1 - 0.051 13.5 1.3 0.06 13.2 1.3 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF4607 PF15380.6 GBG82553.1 - 0.071 12.6 2.0 0.096 12.1 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) PA26 PF04636.13 GBG82553.1 - 0.52 9.2 3.9 0.58 9.0 3.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) VIR_N PF15912.5 GBG82553.1 - 0.87 9.1 5.6 1.2 8.7 5.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Presenilin PF01080.17 GBG82553.1 - 1.2 7.9 2.5 1.3 7.7 2.5 1.1 1 0 0 1 1 1 0 Presenilin AAA_23 PF13476.6 GBG82553.1 - 1.3 9.5 14.2 1.7 9.1 14.2 1.2 1 0 0 1 1 1 0 AAA domain DUF3323 PF11796.8 GBG82553.1 - 2 8.3 9.8 2.5 7.9 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) PIEZO PF15917.5 GBG82553.1 - 3.7 7.0 11.4 4.9 6.6 11.4 1.1 1 0 0 1 1 1 0 Piezo XRN_M PF17846.1 GBG82553.1 - 6.4 5.6 8.7 7.6 5.4 8.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain V_ATPase_I PF01496.19 GBG82553.1 - 6.9 4.4 6.1 7.4 4.4 6.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RVT_1 PF00078.27 GBG82554.1 - 2.5e-29 102.4 0.1 3.9e-29 101.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC PF07967.13 GBG82555.1 - 1.7e-34 118.7 0.3 1.4e-33 115.7 0.0 2.4 3 0 0 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.10 GBG82555.1 - 2.3e-05 24.5 3.2 0.13 12.4 0.0 3.8 4 0 0 4 4 4 2 Rsm1-like dsrm PF00035.26 GBG82556.1 - 9.7e-10 39.0 0.0 2.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 GBG82557.1 - 4.4e-10 40.1 0.0 6.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 GBG82557.1 - 0.15 12.3 0.6 3.1 8.1 0.6 2.2 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Sin_N PF04801.13 GBG82558.1 - 0.22 10.7 3.2 0.22 10.7 3.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF3381 PF11861.8 GBG82558.1 - 3.6 7.4 10.9 4.9 6.9 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.14 GBG82558.1 - 4.6 5.4 6.1 4.4 5.5 6.1 1.0 1 0 0 1 1 1 0 CDC45-like protein BAH PF01426.18 GBG82559.1 - 4.7e-08 32.9 0.0 1.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 BAH domain Polo_box_3 PF18544.1 GBG82559.1 - 0.014 16.0 0.1 0.058 14.0 0.1 2.0 1 0 0 1 1 1 0 Polo box domain zf-CCHC PF00098.23 GBG82561.1 - 0.013 15.5 7.4 0.034 14.2 7.4 1.7 1 0 0 1 1 1 0 Zinc knuckle BT1 PF03092.16 GBG82561.1 - 0.1 10.8 5.4 0.13 10.5 5.4 1.1 1 0 0 1 1 1 0 BT1 family TAF4 PF05236.14 GBG82562.1 - 0.038 13.7 10.2 0.069 12.9 10.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family FAM76 PF16046.5 GBG82562.1 - 0.042 13.2 9.1 0.059 12.7 9.1 1.1 1 0 0 1 1 1 0 FAM76 protein PspB PF06667.12 GBG82562.1 - 7.2 6.7 11.2 8.3 6.5 0.3 2.7 2 0 0 2 2 2 0 Phage shock protein B RVT_1 PF00078.27 GBG82563.1 - 4.3e-51 173.6 0.1 3.9e-26 92.0 0.0 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82563.1 - 1.1e-50 169.8 0.0 3e-24 85.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82563.1 - 2.9e-48 162.5 0.0 6.7e-23 81.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase AMPK1_CBM PF16561.5 GBG82563.1 - 1.1e-18 67.2 0.5 3.1e-18 65.8 0.5 1.8 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Integrase_H2C2 PF17921.1 GBG82563.1 - 5e-18 65.0 0.4 1.6e-17 63.4 0.4 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82563.1 - 1.9e-07 31.3 0.0 6.2e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DSPc PF00782.20 GBG82563.1 - 7.5e-07 29.0 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Integrin_b_cyt PF08725.11 GBG82563.1 - 0.022 14.4 0.1 4.9 6.9 0.0 2.7 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain gag-asp_proteas PF13975.6 GBG82564.1 - 0.00017 22.1 0.0 0.00048 20.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG82564.1 - 0.0039 17.5 0.1 0.011 16.0 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82564.1 - 0.0054 17.3 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82564.1 - 0.033 14.0 0.2 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease DUF1664 PF07889.12 GBG82564.1 - 0.033 14.2 0.6 3.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 GBG82564.1 - 0.082 13.2 0.2 0.3 11.4 0.1 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein Rx_N PF18052.1 GBG82564.1 - 0.12 12.7 0.7 3.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Rx N-terminal domain zf-CCHC_2 PF13696.6 GBG82564.1 - 0.67 9.8 2.1 1.1 9.2 2.1 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG82565.1 - 2.4e-29 102.4 0.1 3.5e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82565.1 - 4.6e-24 84.4 0.0 1e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82565.1 - 2.6e-15 56.6 0.0 4.7e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG82565.1 - 3.5e-08 33.3 0.0 6.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82565.1 - 1.1e-07 32.3 0.0 2.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82565.1 - 2.5e-05 24.7 0.0 5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82565.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease O-FucT PF10250.9 GBG82566.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase TAF4 PF05236.14 GBG82568.1 - 0.16 11.7 10.0 0.19 11.5 10.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF3464 PF11947.8 GBG82568.1 - 3.9 7.2 6.7 8.2 6.2 6.7 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Mucin PF01456.17 GBG82569.1 - 0.00046 20.2 19.4 0.00087 19.3 19.4 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.12 GBG82569.1 - 0.059 11.4 2.6 0.063 11.3 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DDE_Tnp_4 PF13359.6 GBG82570.1 - 2.8e-21 75.8 0.0 6.2e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82570.1 - 6.8e-09 35.6 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG82571.1 - 0.014 15.7 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain O-FucT PF10250.9 GBG82572.1 - 0.0068 16.1 0.0 0.021 14.5 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Sporozoite_P67 PF05642.11 GBG82572.1 - 2.2 6.3 6.6 3.3 5.7 6.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AF-4 PF05110.13 GBG82572.1 - 3 5.8 11.7 4.5 5.2 11.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Apt1 PF10351.9 GBG82572.1 - 4.6 6.0 6.3 6.6 5.5 6.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PhoLip_ATPase_C PF16212.5 GBG82573.1 - 5.5e-82 275.3 24.3 5.5e-82 275.3 24.3 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 GBG82573.1 - 1.3e-13 50.8 0.0 7e-13 48.5 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GBG82573.1 - 1.6e-10 41.6 2.0 7.7e-05 23.1 0.9 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GBG82573.1 - 0.0019 17.8 2.5 0.0022 17.5 0.0 2.4 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GBG82573.1 - 0.057 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CBFD_NFYB_HMF PF00808.23 GBG82575.1 - 2.3e-22 79.0 0.6 3.6e-22 78.4 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GBG82575.1 - 6.6e-17 62.1 0.4 1.1e-16 61.4 0.4 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 GBG82575.1 - 0.1 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X RRM_1 PF00076.22 GBG82577.1 - 1.4e-27 95.3 0.0 2.9e-14 52.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 GBG82577.1 - 0.00032 20.0 3.3 0.00032 20.0 3.3 5.5 2 1 1 3 3 3 1 RAM signalling pathway protein Limkain-b1 PF11608.8 GBG82577.1 - 0.0014 18.6 0.0 0.0045 17.0 0.0 1.8 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 GBG82577.1 - 0.002 17.9 0.0 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_1 PF00076.22 GBG82578.1 - 1.4e-27 95.3 0.0 2.9e-14 52.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 GBG82578.1 - 0.00032 20.0 3.3 0.00032 20.0 3.3 5.5 2 1 2 4 4 4 1 RAM signalling pathway protein Limkain-b1 PF11608.8 GBG82578.1 - 0.0015 18.6 0.0 0.0045 17.0 0.0 1.8 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 GBG82578.1 - 0.002 17.9 0.0 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_1 PF00076.22 GBG82579.1 - 1.3e-27 95.4 0.0 2.8e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 GBG82579.1 - 0.00031 20.1 3.3 0.00031 20.1 3.3 5.5 2 1 3 5 5 5 1 RAM signalling pathway protein Limkain-b1 PF11608.8 GBG82579.1 - 0.0014 18.7 0.0 0.0044 17.1 0.0 1.9 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 GBG82579.1 - 0.002 18.0 0.0 0.058 13.3 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_1 PF00076.22 GBG82580.1 - 2.2e-24 85.1 0.0 5.1e-11 42.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 GBG82580.1 - 0.00032 20.1 3.3 0.00032 20.1 3.3 5.5 2 1 1 3 3 3 1 RAM signalling pathway protein Limkain-b1 PF11608.8 GBG82580.1 - 0.0014 18.6 0.0 0.0044 17.0 0.0 1.8 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 GBG82580.1 - 0.019 14.8 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 GBG82580.1 - 0.18 11.9 3.9 0.28 11.3 0.0 3.4 3 0 0 3 3 3 0 RNA recognition motif RRM_1 PF00076.22 GBG82581.1 - 1.3e-27 95.4 0.0 2.8e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 GBG82581.1 - 0.00031 20.1 3.3 0.00031 20.1 3.3 5.5 2 1 1 3 3 3 1 RAM signalling pathway protein Limkain-b1 PF11608.8 GBG82581.1 - 0.0014 18.7 0.0 0.0044 17.1 0.0 1.9 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 GBG82581.1 - 0.0019 18.0 0.0 0.058 13.3 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_1 PF00076.22 GBG82582.1 - 1.3e-27 95.4 0.0 2.8e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 GBG82582.1 - 0.00032 20.1 3.3 0.00032 20.1 3.3 5.5 2 1 2 4 4 4 1 RAM signalling pathway protein Limkain-b1 PF11608.8 GBG82582.1 - 0.0014 18.7 0.0 0.0044 17.1 0.0 1.9 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 GBG82582.1 - 0.002 18.0 0.0 0.058 13.2 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_1 PF00076.22 GBG82583.1 - 1.3e-27 95.4 0.0 2.8e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 GBG82583.1 - 0.00032 20.1 3.3 0.00032 20.1 3.3 5.5 2 1 3 5 5 5 1 RAM signalling pathway protein Limkain-b1 PF11608.8 GBG82583.1 - 0.0014 18.7 0.0 0.0044 17.1 0.0 1.9 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 GBG82583.1 - 0.002 18.0 0.0 0.058 13.2 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_1 PF00076.22 GBG82584.1 - 1.3e-27 95.4 0.0 2.8e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 GBG82584.1 - 0.0003 20.1 3.3 0.0003 20.1 3.3 5.4 2 1 3 5 5 5 1 RAM signalling pathway protein Limkain-b1 PF11608.8 GBG82584.1 - 0.0014 18.6 0.0 0.0043 17.1 0.0 1.8 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 GBG82584.1 - 0.002 18.0 0.0 0.057 13.3 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RVT_1 PF00078.27 GBG82585.1 - 3.2e-26 92.2 0.0 4.2e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82585.1 - 1.8e-11 44.0 0.0 3.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82585.1 - 0.00063 20.0 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG82586.1 - 2.3e-08 34.3 4.0 2.3e-08 34.3 4.0 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG82586.1 - 0.00092 19.4 0.9 0.002 18.3 0.9 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82586.1 - 0.0032 17.7 1.6 0.0032 17.7 1.6 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG82586.1 - 0.0051 16.9 0.5 0.0051 16.9 0.5 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG82586.1 - 0.071 13.3 0.7 0.24 11.6 0.7 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG82587.1 - 4.6e-11 42.6 0.0 1.6e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82587.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82587.1 - 0.077 12.6 0.2 0.25 11.0 0.1 1.8 2 0 0 2 2 2 0 Transposase DDE domain Integrase_H2C2 PF17921.1 GBG82588.1 - 3.7e-14 52.6 0.2 8.2e-14 51.5 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82588.1 - 4.2e-05 23.7 0.0 0.0001 22.5 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG82588.1 - 0.00033 21.1 0.0 0.00066 20.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82588.1 - 0.0013 19.4 0.0 0.0031 18.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease PTPRCAP PF15713.5 GBG82588.1 - 0.0021 18.4 4.2 0.0078 16.5 4.2 1.9 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated zf-H2C2 PF09337.10 GBG82588.1 - 0.0082 16.3 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG82588.1 - 0.15 11.8 0.5 0.31 10.9 0.5 1.4 1 0 0 1 1 1 0 Aspartyl protease FAM176 PF14851.6 GBG82588.1 - 2.2 7.9 7.9 6.4 6.4 7.9 1.7 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 GBG82588.1 - 4.3 7.1 9.7 9.3 6.0 9.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 GBG82588.1 - 9 4.5 8.2 13 3.9 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein N6_N4_Mtase PF01555.18 GBG82591.1 - 6e-07 29.4 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 DNA methylase Cons_hypoth95 PF03602.15 GBG82591.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RT_RNaseH PF17917.1 GBG82592.1 - 1.4e-20 73.5 0.0 2.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82592.1 - 3.8e-19 68.6 0.0 7.9e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82592.1 - 1.4e-15 57.2 0.1 3.8e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82592.1 - 6.3e-15 55.4 0.0 1.4e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG82592.1 - 3e-06 27.7 0.0 6.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82592.1 - 0.00022 21.8 0.0 0.0005 20.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG82592.1 - 0.0046 17.1 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG82592.1 - 0.011 15.5 0.9 0.02 14.7 0.9 1.3 1 0 0 1 1 1 0 Aspartyl protease FlaC_arch PF05377.11 GBG82593.1 - 0.0053 17.1 4.1 0.099 13.0 0.1 3.3 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 GBG82593.1 - 0.057 13.3 4.8 0.69 9.8 0.2 3.7 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region CCDC92 PF14916.6 GBG82593.1 - 1.8 8.4 6.1 6.2 6.7 0.8 3.2 2 1 1 3 3 3 0 Coiled-coil domain of unknown function Atg14 PF10186.9 GBG82593.1 - 4.2 6.4 13.9 6.8 5.7 13.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GIT_CC PF16559.5 GBG82593.1 - 7.4 6.5 10.6 1.1 9.2 1.8 2.9 1 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Myb_DNA-bind_4 PF13837.6 GBG82594.1 - 1.9e-09 37.8 0.3 1.9e-09 37.8 0.3 2.5 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82594.1 - 0.028 14.7 0.2 0.083 13.2 0.2 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVT_1 PF00078.27 GBG82596.1 - 1.7e-35 122.5 0.1 3e-35 121.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82596.1 - 3.9e-32 110.3 0.0 8.9e-32 109.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82596.1 - 3.2e-27 94.9 0.0 6.4e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82596.1 - 1.4e-16 60.3 0.0 6.9e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG82596.1 - 1.8e-12 47.5 0.0 3.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82596.1 - 0.021 15.0 0.0 0.068 13.4 0.0 1.9 2 0 0 2 2 2 0 H2C2 zinc finger rve_3 PF13683.6 GBG82596.1 - 0.15 11.8 0.0 0.67 9.8 0.0 2.2 1 0 0 1 1 1 0 Integrase core domain Hydant_A_N PF05378.13 GBG82597.1 - 0.016 14.9 0.8 0.03 14.1 0.8 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF4094 PF13334.6 GBG82597.1 - 0.32 11.4 2.1 0.81 10.2 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) RVT_1 PF00078.27 GBG82598.1 - 1.7e-26 93.1 0.0 2.8e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82598.1 - 3e-22 78.5 0.0 6.6e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82598.1 - 7.9e-19 67.9 0.0 1.5e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-AN1 PF01428.16 GBG82598.1 - 7e-07 29.3 9.6 7e-07 29.3 9.6 2.8 2 1 1 3 3 3 1 AN1-like Zinc finger MetOD1 PF18546.1 GBG82598.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Metanogen output domain 1 Vps39_2 PF10367.9 GBG82599.1 - 1.2e-26 93.3 0.1 3.3e-26 91.9 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 GBG82599.1 - 5.3e-21 75.4 0.0 1.2e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 GBG82599.1 - 1.5e-15 57.4 0.3 5e-15 55.7 0.3 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 GBG82599.1 - 4.9e-07 29.7 0.5 0.00091 19.1 0.0 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_19 PF14559.6 GBG82599.1 - 0.01 16.3 0.0 1 9.9 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat NPR3 PF03666.13 GBG82599.1 - 0.017 13.9 10.4 0.038 12.8 10.4 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2052 PF09747.9 GBG82599.1 - 0.19 11.8 32.6 2 8.5 27.3 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 GBG82599.1 - 0.48 9.1 12.6 0.85 8.3 12.6 1.3 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG82599.1 - 1 7.5 37.9 0.017 13.4 27.0 2.0 2 0 0 2 2 2 0 Nop14-like family Red1 PF07964.11 GBG82599.1 - 1.1 7.4 12.6 1.6 6.8 12.6 1.1 1 0 0 1 1 1 0 Rec10 / Red1 SDA1 PF05285.12 GBG82599.1 - 1.1 8.6 44.3 0.078 12.4 33.8 2.2 2 0 0 2 2 2 0 SDA1 Hid1 PF12722.7 GBG82599.1 - 2.1 6.3 8.7 3.2 5.8 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BUD22 PF09073.10 GBG82599.1 - 5.2 6.3 34.4 28 3.9 0.0 2.5 2 0 0 2 2 2 0 BUD22 Mpp10 PF04006.12 GBG82599.1 - 9.6 4.5 42.8 0.46 8.9 34.0 2.0 2 0 0 2 2 2 0 Mpp10 protein PolyA_pol_RNAbd PF12627.7 GBG82600.1 - 1.3e-11 44.0 0.2 2.5e-11 43.2 0.2 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A PolyA_pol PF01743.20 GBG82600.1 - 4.9e-10 39.9 0.0 2.5e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Poly A polymerase head domain SGP PF17228.2 GBG82600.1 - 0.61 11.0 18.6 1.4 9.8 18.6 1.5 1 0 0 1 1 1 0 Sulphur globule protein Myb_DNA-bind_4 PF13837.6 GBG82601.1 - 6.2e-09 36.1 4.3 8.4e-09 35.7 1.8 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG82601.1 - 0.00011 22.2 0.7 0.00029 20.8 0.7 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82601.1 - 0.045 14.1 1.4 0.092 13.1 0.2 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Es2 PF09751.9 GBG82604.1 - 0.0027 17.5 12.1 0.0035 17.1 12.1 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 CDC27 PF09507.10 GBG82604.1 - 0.023 14.1 23.4 0.024 14.1 23.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Myc_N PF01056.18 GBG82604.1 - 0.088 12.7 15.6 0.13 12.1 15.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region RXLR PF16810.5 GBG82604.1 - 0.11 12.9 7.2 0.18 12.2 7.2 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DUF1690 PF07956.11 GBG82604.1 - 0.13 12.6 18.8 0.25 11.8 18.8 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) FAM60A PF15396.6 GBG82604.1 - 0.18 11.8 8.7 0.22 11.5 8.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CLPTM1 PF05602.12 GBG82604.1 - 0.32 10.0 3.0 0.43 9.6 3.0 1.3 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Pox_Ag35 PF03286.14 GBG82604.1 - 0.46 10.2 17.6 0.71 9.6 17.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HAUS6_N PF14661.6 GBG82604.1 - 0.78 9.3 13.9 1.3 8.6 13.9 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Sec62 PF03839.16 GBG82604.1 - 1.2 8.6 11.6 1.6 8.2 11.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 GBG82604.1 - 1.9 7.6 6.3 2 7.5 6.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.10 GBG82604.1 - 2 8.7 21.0 2.9 8.2 21.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 GBG82604.1 - 2.1 8.5 5.8 2.3 8.3 5.8 1.2 1 0 0 1 1 1 0 DDHD domain Atg14 PF10186.9 GBG82604.1 - 2.9 6.9 9.4 3.9 6.5 9.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Presenilin PF01080.17 GBG82604.1 - 3.3 6.4 12.6 3.6 6.2 12.6 1.1 1 0 0 1 1 1 0 Presenilin EBV-NA3 PF05009.12 GBG82604.1 - 3.5 7.1 8.1 4.6 6.7 8.1 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Cellulose_synt PF03552.14 GBG82604.1 - 3.5 6.0 5.7 3.7 5.9 5.7 1.0 1 0 0 1 1 1 0 Cellulose synthase PA26 PF04636.13 GBG82604.1 - 3.8 6.3 13.3 4.6 6.1 13.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PPL5 PF18168.1 GBG82604.1 - 4.2 6.6 10.8 5.2 6.3 10.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 CSRNP_N PF16019.5 GBG82604.1 - 4.5 7.1 9.5 5.6 6.8 9.5 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus TRAP_alpha PF03896.16 GBG82604.1 - 4.6 6.3 12.7 5.9 6.0 12.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Membralin PF09746.9 GBG82604.1 - 6.1 5.8 6.5 6.1 5.8 6.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein AAA_11 PF13086.6 GBG82604.1 - 7.2 6.3 12.7 11 5.7 12.7 1.4 1 0 0 1 1 1 0 AAA domain XRN_M PF17846.1 GBG82604.1 - 7.6 5.4 13.6 9 5.1 13.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RNA_pol_3_Rpc31 PF11705.8 GBG82604.1 - 8.8 6.5 32.5 1.4 9.2 28.7 1.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CAF1 PF04857.20 GBG82604.1 - 9.6 5.3 12.7 11 5.0 12.7 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease RVT_1 PF00078.27 GBG82605.1 - 4.7e-09 36.1 0.0 8.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG82605.1 - 2.6e-08 34.3 0.5 8.5e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82605.1 - 2.4e-05 24.9 0.0 6.7e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82605.1 - 0.00034 20.4 1.9 0.0004 20.2 0.7 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG82605.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Mito_carr PF00153.27 GBG82606.1 - 8e-46 153.9 6.7 2e-20 72.5 0.1 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_8 PF13833.6 GBG82606.1 - 1.1e-07 31.6 0.2 0.00057 19.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 GBG82606.1 - 1.3e-05 25.5 0.1 0.012 16.1 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG82606.1 - 1.4e-05 24.3 1.2 7.9e-05 21.9 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GBG82606.1 - 1.9e-05 24.2 0.0 0.00039 20.1 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 GBG82606.1 - 0.0088 15.5 0.2 0.019 14.5 0.2 1.5 1 0 0 1 1 1 1 EF hand Serine_protease PF18405.1 GBG82606.1 - 0.099 11.8 0.1 0.42 9.7 0.1 1.8 1 1 0 1 1 1 0 Gammaproteobacterial serine protease Methyltransf_24 PF13578.6 GBG82609.1 - 5.9e-15 56.2 0.0 1.4e-14 55.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 GBG82609.1 - 0.0065 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Myb_DNA-bind_4 PF13837.6 GBG82612.1 - 0.18 12.2 1.3 0.85 10.0 0.7 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG82613.1 - 9.6e-13 48.1 0.5 2.5e-12 46.7 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82613.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82613.1 - 8.6e-05 22.3 0.1 0.00016 21.4 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain Pro-MCH PF05824.12 GBG82613.1 - 0.0088 15.9 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Pro-melanin-concentrating hormone (Pro-MCH) Myb_DNA-bind_4 PF13837.6 GBG82614.1 - 5.8e-09 36.2 1.5 8.7e-09 35.6 1.5 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG82614.1 - 8.6e-05 22.5 0.2 0.00012 22.1 0.2 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82614.1 - 0.00016 21.9 0.2 0.00028 21.1 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG82614.1 - 0.0003 21.0 0.2 0.00049 20.3 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG82614.1 - 0.00061 19.9 0.2 0.0014 18.8 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Defensin_big PF14862.6 GBG82614.1 - 0.0098 16.2 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 1 Big defensin FoP_duplication PF13865.6 GBG82614.1 - 0.18 12.4 4.8 0.42 11.2 4.8 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RVT_1 PF00078.27 GBG82616.1 - 7.1e-29 100.9 0.1 1.5e-28 99.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82616.1 - 1e-23 83.2 0.0 2.6e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82616.1 - 2.6e-22 79.1 0.0 7.3e-22 77.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG82616.1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF4407 PF14362.6 GBG82616.1 - 0.87 8.9 11.1 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Integrase_H2C2 PF17921.1 GBG82617.1 - 3.2e-16 59.2 0.1 7.1e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82617.1 - 3.8e-07 30.3 0.0 8.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG82617.1 - 5.1e-06 26.9 0.0 9.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG82617.1 - 0.00025 20.6 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG82617.1 - 0.00026 21.6 0.0 0.00052 20.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG82617.1 - 0.0021 18.2 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG82617.1 - 0.038 13.8 0.6 0.073 12.9 0.6 1.4 1 0 0 1 1 1 0 Aspartyl protease Sarcoglycan_1 PF04790.13 GBG82620.1 - 0.14 11.5 1.7 0.22 10.8 1.7 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Topo_Zn_Ribbon PF08272.11 GBG82621.1 - 0.29 10.8 2.2 0.34 10.6 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Exotox-A_target PF09102.10 GBG82625.1 - 0.067 13.2 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Exotoxin A, targeting EIIBC-GUT_N PF03612.14 GBG82625.1 - 1.1 9.0 4.8 2.1 8.0 4.8 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus LAT2 PF15703.5 GBG82625.1 - 2.4 8.0 12.6 5.3 6.9 12.1 1.8 1 1 0 1 1 1 0 Linker for activation of T-cells family member 2 Myb_DNA-bind_4 PF13837.6 GBG82626.1 - 3.2e-08 33.8 0.7 6.2e-08 32.9 0.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-CCHC_2 PF13696.6 GBG82627.1 - 0.006 16.4 1.7 0.006 16.4 1.7 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 GBG82627.1 - 0.012 15.7 1.0 0.021 14.9 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2362 PF10154.9 GBG82627.1 - 0.024 13.6 8.3 0.031 13.2 8.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) HSP70 PF00012.20 GBG82627.1 - 2.1 6.4 14.4 2.7 6.0 14.4 1.1 1 0 0 1 1 1 0 Hsp70 protein Borrelia_P83 PF05262.11 GBG82627.1 - 3.3 6.1 18.1 4.2 5.8 18.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 GBG82627.1 - 4.5 6.5 10.0 0.91 8.8 6.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Asp-B-Hydro_N PF05279.11 GBG82627.1 - 5.6 7.0 16.3 10 6.1 16.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ALMT PF11744.8 GBG82627.1 - 9.7 4.9 8.3 13 4.5 8.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TIM PF00121.18 GBG82630.1 - 8e-90 300.5 0.2 9.2e-90 300.3 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 GBG82630.1 - 0.0038 16.7 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 CutC family RSN1_7TM PF02714.15 GBG82632.1 - 3e-75 253.1 16.7 4.3e-75 252.5 16.7 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GBG82632.1 - 1.2e-41 142.9 0.1 1.2e-41 142.9 0.1 4.2 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GBG82632.1 - 2.3e-34 118.4 1.2 6.6e-34 116.9 1.2 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport Bestrophin PF01062.21 GBG82632.1 - 0.02 14.3 0.2 0.05 13.0 0.2 1.6 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Glutaredoxin PF00462.24 GBG82633.1 - 1.4e-38 130.9 0.0 1.1e-16 60.7 0.0 3.4 3 0 0 3 3 3 3 Glutaredoxin Thioredoxin PF00085.20 GBG82633.1 - 2.4e-18 66.0 0.1 1.1e-17 63.8 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GBG82633.1 - 6.7e-06 26.5 0.1 0.0001 22.7 0.1 2.9 3 1 0 3 3 3 1 Thioredoxin-like domain GST_N_3 PF13417.6 GBG82633.1 - 9.9e-05 22.7 0.0 0.021 15.2 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.15 GBG82633.1 - 0.00025 21.1 0.0 0.39 10.9 0.0 2.5 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein OST3_OST6 PF04756.13 GBG82633.1 - 0.00029 20.3 0.1 0.00044 19.7 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GBG82633.1 - 0.0011 19.2 0.6 0.0053 16.9 0.4 2.2 2 0 0 2 2 2 1 Thioredoxin-like ZinT PF09223.11 GBG82633.1 - 0.0071 16.2 0.1 1.2 9.0 0.0 2.5 2 1 0 2 2 2 1 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment Thioredoxin_8 PF13905.6 GBG82633.1 - 0.0096 16.2 0.1 0.038 14.3 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 GBG82633.1 - 0.027 14.4 0.0 1.1 9.2 0.0 3.0 3 1 0 3 3 3 0 AhpC/TSA family Thioredoxin_3 PF13192.6 GBG82633.1 - 0.049 13.7 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain RdRP PF05183.12 GBG82633.1 - 0.063 11.9 0.0 5.6 5.5 0.0 2.1 1 1 1 2 2 2 0 RNA dependent RNA polymerase Flavodoxin_1 PF00258.25 GBG82633.1 - 0.099 12.9 0.1 2.8 8.1 0.0 2.5 2 1 0 2 2 2 0 Flavodoxin CEP63 PF17045.5 GBG82636.1 - 0.0069 16.3 3.5 0.0084 16.0 3.5 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa APG6_N PF17675.1 GBG82636.1 - 0.024 15.2 7.9 0.03 14.8 7.0 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region CP12 PF02672.15 GBG82636.1 - 0.026 15.3 3.3 0.89 10.3 1.0 2.1 2 0 0 2 2 2 0 CP12 domain Cu-binding_MopE PF11617.8 GBG82636.1 - 0.027 14.7 0.3 0.063 13.5 0.3 1.6 1 0 0 1 1 1 0 Putative metal-binding motif DUF4795 PF16043.5 GBG82636.1 - 0.087 12.4 3.5 0.1 12.2 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) APG6_N PF17675.1 GBG82637.1 - 0.0059 17.1 4.3 0.0068 16.9 4.3 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Cu-binding_MopE PF11617.8 GBG82637.1 - 0.038 14.2 0.3 0.085 13.0 0.3 1.6 1 0 0 1 1 1 0 Putative metal-binding motif DUF659 PF04937.15 GBG82640.1 - 3.2e-17 62.8 0.0 4.6e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) BNR_3 PF13859.6 GBG82640.1 - 0.23 10.7 0.1 0.4 9.9 0.1 1.3 1 0 0 1 1 1 0 BNR repeat-like domain NINJA_B PF16136.5 GBG82640.1 - 0.27 11.6 3.0 28 5.1 0.3 3.3 2 0 0 2 2 2 0 Putative nuclear localisation signal RT_RNaseH_2 PF17919.1 GBG82641.1 - 1.2e-10 41.3 0.0 4e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82641.1 - 1.2e-09 38.4 0.0 7.8e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82641.1 - 2.9e-09 36.8 0.0 4.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG82641.1 - 1.6e-07 31.7 0.1 4.5e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82641.1 - 1.5e-05 25.5 0.1 3.5e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82641.1 - 0.00019 21.2 0.1 0.00036 20.3 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82641.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Thioredoxin PF00085.20 GBG82642.1 - 1.8e-63 210.9 0.0 1.1e-30 105.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 GBG82642.1 - 6.1e-24 84.7 2.3 1e-23 84.0 2.3 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 GBG82642.1 - 5e-11 42.5 0.0 3.9e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GBG82642.1 - 1.1e-09 38.7 0.5 0.0061 17.0 0.1 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG82642.1 - 1.3e-08 35.1 0.0 0.017 15.4 0.0 3.5 2 2 2 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 GBG82642.1 - 9.2e-07 28.8 0.0 0.043 13.7 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 GBG82642.1 - 3.2e-06 27.2 0.3 0.058 13.6 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like HyaE PF07449.11 GBG82642.1 - 0.0045 16.9 0.0 5.7 7.0 0.0 3.1 4 0 0 4 4 4 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 GBG82642.1 - 0.0091 15.7 0.2 1 9.1 0.0 2.3 2 0 0 2 2 2 1 Redoxin ERp29_N PF07912.13 GBG82642.1 - 0.026 14.7 0.1 1.2 9.3 0.0 2.7 2 1 0 2 2 2 0 ERp29, N-terminal domain TraF PF13728.6 GBG82642.1 - 0.043 13.6 0.0 0.83 9.4 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 GBG82642.1 - 0.21 11.4 0.0 9.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin DDE_Tnp_4 PF13359.6 GBG82643.1 - 1.2e-26 93.3 0.0 2.9e-26 92.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82643.1 - 5.3e-15 55.6 0.0 8.7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82643.1 - 0.0032 17.2 0.2 0.028 14.0 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG82644.1 - 7.1e-27 94.0 0.0 2e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82644.1 - 3.9e-15 56.0 0.0 5.8e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82644.1 - 0.002 17.8 0.2 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG82645.1 - 5.2e-08 33.2 4.8 6.4e-08 32.9 1.6 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82645.1 - 0.0006 20.1 0.7 0.027 14.8 0.2 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG82645.1 - 0.00075 19.7 1.3 0.0014 18.8 1.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG82645.1 - 0.004 17.2 0.1 0.0098 15.9 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG82645.1 - 0.023 14.9 0.1 0.058 13.6 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain G-patch PF01585.23 GBG82646.1 - 7.8e-14 51.3 0.3 2.5e-13 49.7 0.3 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GBG82646.1 - 0.0088 16.1 0.2 0.0088 16.1 0.2 3.2 4 0 0 4 4 4 1 G-patch domain zf-RING_4 PF14570.6 GBG82647.1 - 2.4e-17 62.5 11.6 2.4e-17 62.5 11.6 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 GBG82647.1 - 0.00076 19.3 10.9 0.00093 19.0 6.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG82647.1 - 0.0021 18.3 15.6 0.0029 17.9 11.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-UDP PF14569.6 GBG82647.1 - 0.065 13.3 2.9 0.2 11.8 2.9 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 GBG82647.1 - 0.62 10.3 2.1 1.2 9.4 2.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Baculo_IE-1 PF05290.11 GBG82647.1 - 0.65 9.9 4.8 1.4 8.9 4.8 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Gpr1_Fun34_YaaH PF01184.19 GBG82648.1 - 2.1e-51 174.5 14.4 2.7e-51 174.1 14.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF998 PF06197.13 GBG82648.1 - 0.0013 18.4 7.3 0.0013 18.4 7.3 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF998) Cytochrom_B561 PF03188.16 GBG82648.1 - 2.4 8.3 8.5 0.73 10.0 1.0 2.8 1 1 2 3 3 3 0 Eukaryotic cytochrome b561 Gpr1_Fun34_YaaH PF01184.19 GBG82649.1 - 4.5e-35 121.1 6.2 6.7e-35 120.6 6.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 GBG82650.1 - 4.6e-49 166.8 15.5 8.3e-49 166.0 15.5 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family RT_RNaseH_2 PF17919.1 GBG82650.1 - 3e-28 97.8 0.0 6.8e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82650.1 - 9.6e-26 90.1 0.0 1.9e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82650.1 - 9.9e-26 90.6 0.0 1.6e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhoLip_ATPase_C PF16212.5 GBG82650.1 - 6.6 6.4 15.3 0.68 9.6 9.8 1.9 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal Gpr1_Fun34_YaaH PF01184.19 GBG82653.1 - 1.3e-49 168.6 15.1 1.7e-49 168.2 15.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DAO PF01266.24 GBG82654.1 - 2.9e-39 135.7 0.7 4.1e-39 135.2 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GBG82654.1 - 1.3e-07 31.7 0.2 4.6e-07 30.0 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GBG82654.1 - 1.6e-06 27.5 0.0 3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GBG82654.1 - 3.7e-06 26.4 0.1 0.00024 20.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GBG82654.1 - 9.9e-05 21.7 0.3 0.00019 20.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 GBG82654.1 - 0.00045 19.4 0.2 0.0015 17.7 0.2 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GBG82654.1 - 0.00082 18.5 0.1 0.053 12.6 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GBG82654.1 - 0.0015 17.7 0.5 0.003 16.7 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 GBG82654.1 - 0.0016 19.0 0.2 0.0036 17.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GBG82654.1 - 0.0073 15.7 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GBG82654.1 - 0.016 14.5 0.1 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 GBG82654.1 - 0.032 13.5 0.1 0.056 12.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 GBG82654.1 - 0.054 13.5 0.2 12 5.8 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 GBG82654.1 - 0.081 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 GBG82654.1 - 0.089 12.0 0.2 0.63 9.2 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GBG82654.1 - 0.16 11.6 0.2 0.66 9.6 0.3 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Zip PF02535.22 GBG82655.1 - 9.2e-28 97.4 3.1 1.2e-27 97.0 3.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Phage_holin_5_2 PF16079.5 GBG82655.1 - 4.9 7.6 6.8 3.5 8.0 0.5 3.2 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V ABC_tran PF00005.27 GBG82656.1 - 3.2e-13 50.4 0.0 1.9e-12 47.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG82656.1 - 0.00033 20.6 0.1 0.00069 19.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 GBG82656.1 - 0.0028 17.6 0.0 0.0063 16.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 GBG82656.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 GBG82656.1 - 0.016 14.6 0.5 3.3 7.1 0.1 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GBG82656.1 - 0.033 14.6 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 GBG82656.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG82656.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RVT_1 PF00078.27 GBG82658.1 - 2.9e-21 76.0 0.1 4.9e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG82658.1 - 3.5e-07 30.7 0.0 5.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82658.1 - 1.4e-06 28.8 0.0 2.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82658.1 - 0.0024 17.6 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82658.1 - 0.0079 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG82658.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF5095 PF17016.5 GBG82658.1 - 0.079 12.6 1.3 0.55 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) MORN PF02493.20 GBG82659.1 - 1.1e-39 131.9 68.8 1.1e-06 28.1 2.9 9.4 9 0 0 9 9 9 7 MORN repeat Pirin_C_2 PF17954.1 GBG82659.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Spore_YtfJ PF09579.10 GBG82659.1 - 2.5 8.3 4.6 6.1 7.1 0.8 2.7 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) DUF3048_C PF17479.2 GBG82659.1 - 4.5 7.7 8.3 10 6.5 0.1 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain Myb_DNA-bind_4 PF13837.6 GBG82660.1 - 3.4e-06 27.3 2.6 0.00013 22.3 1.6 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82660.1 - 0.34 11.3 2.8 0.5 10.7 0.4 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG82660.1 - 0.75 9.9 6.1 1.3 9.1 4.9 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Integrase_H2C2 PF17921.1 GBG82661.1 - 3.7e-14 52.6 0.1 9.5e-14 51.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82661.1 - 6.4e-14 52.2 0.0 2.1e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82661.1 - 0.0038 17.4 0.0 0.0087 16.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger CDC27 PF09507.10 GBG82662.1 - 0.23 10.8 62.7 0.46 9.8 62.7 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAM60A PF15396.6 GBG82662.1 - 5.4 7.0 27.3 4 7.4 6.9 2.1 2 0 0 2 2 2 0 Protein Family FAM60A RVT_1 PF00078.27 GBG82665.1 - 1.8e-33 116.0 0.0 4.5e-33 114.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82665.1 - 1.1e-32 112.1 0.2 3e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82665.1 - 1.6e-30 105.5 0.0 3.6e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG82665.1 - 7.6e-08 32.2 0.0 2e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82665.1 - 9.2e-06 26.2 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82665.1 - 0.00021 21.8 0.0 0.0005 20.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG82665.1 - 0.00072 19.4 0.1 0.002 17.9 0.1 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 GBG82667.1 - 5.2e-25 87.4 0.0 1.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82667.1 - 4.7e-19 68.6 0.0 1.1e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG82667.1 - 5.9e-06 26.8 0.0 2.5e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82667.1 - 1.3e-05 25.6 0.0 4.3e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82667.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82667.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG82667.1 - 0.0085 15.6 0.3 0.061 12.8 0.0 2.3 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rubis-subs-bind PF09273.11 GBG82668.1 - 8.6e-08 32.9 0.1 1.6e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 GBG82668.1 - 0.16 12.4 0.0 0.38 11.1 0.0 1.6 2 0 0 2 2 2 0 SET domain RVT_1 PF00078.27 GBG82669.1 - 9.3e-28 97.2 0.1 1.4e-27 96.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG82669.1 - 2.9e-08 34.2 0.0 5.4e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82669.1 - 6.1e-08 33.2 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82669.1 - 2e-06 27.6 0.0 5.1e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82669.1 - 1.2e-05 25.1 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG82670.1 - 3.9e-26 92.0 0.1 7e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82670.1 - 8.5e-19 67.8 1.1 1.8e-18 66.8 1.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82670.1 - 4.5e-11 42.7 0.1 1.1e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SET PF00856.28 GBG82670.1 - 0.063 13.7 0.1 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 SET domain RT_RNaseH PF17917.1 GBG82671.1 - 1.1e-22 80.3 0.0 2.4e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82671.1 - 1.8e-18 66.4 0.0 3.9e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82671.1 - 3.8e-16 59.3 0.0 1.6e-15 57.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG82671.1 - 1.9e-07 30.9 0.0 4.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82671.1 - 1.1e-06 29.2 0.0 2.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82671.1 - 1.7e-05 25.2 0.0 7.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82671.1 - 0.00074 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG82671.1 - 0.013 15.8 0.4 0.088 13.1 0.0 2.6 3 1 1 4 4 4 0 Retrotransposon gag protein Epimerase PF01370.21 GBG82672.1 - 2.2e-11 43.7 0.0 5.3e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GBG82672.1 - 2e-10 40.3 0.0 3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GBG82672.1 - 0.00037 20.0 0.0 0.00093 18.7 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GBG82672.1 - 0.001 18.3 0.3 0.0025 17.0 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GBG82672.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Peptidase_M24_C PF16188.5 GBG82673.1 - 1e-21 76.8 0.0 2.1e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N_2 PF16189.5 GBG82673.1 - 1.4e-16 61.0 0.1 6.3e-09 36.1 0.0 3.3 3 1 1 4 4 4 2 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 GBG82673.1 - 2.4e-16 60.6 0.0 7.6e-16 59.0 0.0 1.9 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 GBG82673.1 - 5.4e-05 23.0 0.0 9.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 DTW PF03942.15 GBG82675.1 - 3.1e-31 108.6 0.0 5.5e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 DTW domain MRI PF15325.6 GBG82675.1 - 0.0057 17.7 0.4 0.0057 17.7 0.4 3.1 4 0 0 4 4 4 1 Modulator of retrovirus infection Iso_dh PF00180.20 GBG82676.1 - 1.1e-72 245.1 0.0 1.4e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Vps53_N PF04100.12 GBG82677.1 - 2.4e-134 448.1 0.0 3.3e-134 447.6 0.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 GBG82677.1 - 1.9e-05 24.1 5.3 4.7e-05 22.8 5.3 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG7 PF10191.9 GBG82677.1 - 2.2e-05 23.0 0.1 2.2e-05 23.0 0.1 1.9 3 0 0 3 3 3 1 Golgi complex component 7 (COG7) DUF2451 PF10474.9 GBG82677.1 - 0.018 14.8 0.0 0.055 13.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) COG5 PF10392.9 GBG82677.1 - 0.12 12.6 1.3 0.33 11.1 1.3 1.8 1 0 0 1 1 1 0 Golgi transport complex subunit 5 MapZ_EC1 PF18041.1 GBG82677.1 - 0.72 10.1 7.0 2.3 8.5 0.6 3.6 3 1 1 4 4 4 0 MapZ extracellular domain 1 Occludin_ELL PF07303.13 GBG82677.1 - 1.4 9.7 4.2 7.8 7.3 0.9 2.8 1 1 1 2 2 2 0 Occludin homology domain Tropomyosin_1 PF12718.7 GBG82677.1 - 1.5 9.0 4.2 3.2 7.9 0.4 2.9 2 1 1 3 3 3 0 Tropomyosin like Cullin PF00888.22 GBG82678.1 - 5.9e-222 738.7 12.2 7.3e-222 738.3 12.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GBG82678.1 - 5.4e-27 93.6 1.7 5.4e-27 93.6 1.7 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain PTA_PTB PF01515.19 GBG82678.1 - 0.098 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase Cullin PF00888.22 GBG82679.1 - 9.7e-31 107.1 1.9 1.2e-30 106.7 1.9 1.0 1 0 0 1 1 1 1 Cullin family Ribosomal_L2_C PF03947.18 GBG82679.1 - 1.5e-05 25.2 1.3 2.8e-05 24.3 1.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain SecA_SW PF07516.13 GBG82679.1 - 0.14 12.2 2.2 0.27 11.3 1.2 1.8 1 1 1 2 2 2 0 SecA Wing and Scaffold domain GDP_Man_Dehyd PF16363.5 GBG82680.1 - 5.3e-75 252.9 0.0 9e-70 235.7 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG82680.1 - 6.1e-67 225.6 0.2 8.6e-55 185.8 0.1 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GBG82680.1 - 4.5e-29 101.3 0.0 1.7e-26 92.8 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GBG82680.1 - 6.9e-28 97.6 0.0 2.5e-17 62.9 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GBG82680.1 - 5.2e-27 94.7 0.0 3.8e-20 72.2 0.0 3.2 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GBG82680.1 - 1.7e-22 79.8 0.1 5.3e-17 61.8 0.0 3.1 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GBG82680.1 - 0.00051 20.0 0.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 GBG82680.1 - 0.0015 18.0 0.0 1.5 8.3 0.0 3.7 4 0 0 4 4 4 1 short chain dehydrogenase KR PF08659.10 GBG82680.1 - 0.15 12.0 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 KR domain Sec1 PF00995.23 GBG82681.1 - 1e-13 51.4 0.0 5.6e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Sec1 family Arm PF00514.23 GBG82682.1 - 4e-10 39.4 22.1 0.28 11.3 0.2 12.3 14 0 0 14 14 14 3 Armadillo/beta-catenin-like repeat zf-C3HC4_4 PF15227.6 GBG82682.1 - 4.1e-06 26.9 4.6 4.1e-06 26.9 4.6 2.9 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GBG82682.1 - 5.3e-06 26.2 7.7 7.9e-06 25.6 5.0 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG82682.1 - 6.4e-06 26.1 5.9 6.4e-06 26.1 5.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG82682.1 - 3.7e-05 23.5 7.8 5.7e-05 22.9 5.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 GBG82682.1 - 0.00017 21.7 0.0 0.00041 20.5 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-C3HC4_3 PF13920.6 GBG82682.1 - 0.00045 20.0 7.0 0.00045 20.0 7.0 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) LRIF1 PF15741.5 GBG82682.1 - 0.017 13.7 2.7 0.028 13.0 2.7 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 zf-RING_2 PF13639.6 GBG82682.1 - 1.1 9.6 10.4 0.36 11.2 5.3 3.0 3 0 0 3 3 2 0 Ring finger domain zf-CRD PF17979.1 GBG82682.1 - 2.6 8.1 11.9 0.035 14.2 0.9 3.1 3 0 0 3 3 3 0 Cysteine rich domain with multizinc binding regions DUF753 PF05444.12 GBG82682.1 - 9.2 6.2 12.5 0.14 12.1 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF753) RT_RNaseH_2 PF17919.1 GBG82683.1 - 4.7e-25 87.5 0.0 8.1e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82683.1 - 1.4e-22 80.0 0.0 4e-22 78.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82683.1 - 7.4e-12 45.3 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82684.1 - 8.4e-21 74.2 0.0 7.8e-20 71.1 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82684.1 - 3.5e-18 65.5 0.0 1.2e-17 63.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82684.1 - 3.3e-11 43.1 0.1 8.9e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82684.1 - 3.1e-06 27.4 0.0 7.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82684.1 - 0.25 11.6 0.3 1 9.6 0.0 2.3 2 0 0 2 2 2 0 H2C2 zinc finger DNA_ligase_A_N PF04675.14 GBG82685.1 - 8.6e-33 114.1 0.1 5.3e-32 111.5 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_N PF04675.14 GBG82686.1 - 4.3e-32 111.8 0.1 7.2e-32 111.1 0.0 1.4 2 0 0 2 2 2 1 DNA ligase N terminus Rop PF01815.16 GBG82686.1 - 0.1 12.5 0.6 6.6 6.7 0.1 2.5 1 1 1 2 2 2 0 Rop protein Glyco_transf_5 PF08323.11 GBG82687.1 - 5.8e-39 134.3 0.0 1.1e-29 103.9 0.0 2.2 1 1 1 2 2 2 2 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 GBG82687.1 - 0.041 13.9 0.0 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Apt1 PF10351.9 GBG82687.1 - 0.21 10.4 3.4 0.27 10.0 3.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC24 PF15669.5 GBG82687.1 - 0.43 10.4 4.2 0.75 9.6 4.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Dimer_Tnp_hAT PF05699.14 GBG82689.1 - 1.4e-05 24.8 0.1 2.5e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region BTP PF05232.12 GBG82690.1 - 0.073 13.1 1.1 0.073 13.1 1.1 3.9 4 1 0 4 4 4 0 Chlorhexidine efflux transporter Ni_hydr_CYTB PF01292.20 GBG82690.1 - 0.15 11.6 7.5 0.051 13.2 4.3 2.0 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 PG_binding_1 PF01471.18 GBG82692.1 - 7.4e-29 99.7 0.1 2.7e-14 53.1 0.0 2.7 3 0 0 3 3 3 2 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 GBG82692.1 - 1.5e-05 25.2 0.1 0.83 10.0 0.0 3.6 1 1 3 4 4 4 3 Predicted Peptidoglycan domain Glyco_transf_5 PF08323.11 GBG82693.1 - 2.5e-43 148.6 0.0 8e-43 146.9 0.0 1.9 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG82693.1 - 9.2e-17 61.1 0.0 1.6e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG82693.1 - 2.9e-13 50.4 0.0 6.7e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 TIG PF01833.24 GBG82694.1 - 5.5e-20 71.2 0.0 4e-10 39.6 0.3 3.3 2 1 0 2 2 2 2 IPT/TIG domain Glyco_transf_29 PF00777.18 GBG82694.1 - 1.7e-13 50.6 0.0 1.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 29 (sialyltransferase) TT_ORF2 PF02957.15 GBG82694.1 - 0.55 11.1 11.2 2.8 8.9 4.0 2.8 2 0 0 2 2 2 0 TT viral ORF2 DUF2457 PF10446.9 GBG82695.1 - 0.099 11.8 18.3 0.12 11.6 18.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 GBG82695.1 - 0.68 9.5 8.9 0.71 9.4 8.9 1.2 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 GBG82695.1 - 1.4 7.4 7.1 1.3 7.5 7.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 GBG82695.1 - 5.4 6.3 17.3 6.4 6.1 17.3 1.1 1 0 0 1 1 1 0 SDA1 Pes-10 PF07149.11 GBG82695.1 - 6.4 5.7 8.4 6.3 5.7 8.4 1.1 1 0 0 1 1 1 0 Pes-10 PBP1_TM PF14812.6 GBG82695.1 - 8.7 6.8 16.9 0.76 10.2 11.9 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GARS_A PF01071.19 GBG82696.1 - 1.8e-77 259.6 0.3 1.4e-76 256.6 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 GBG82696.1 - 3.4e-31 107.9 0.0 8e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 GBG82696.1 - 4.8e-27 94.1 0.1 2.1e-26 92.0 0.1 2.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 GBG82696.1 - 4.1e-07 29.7 0.0 7.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 GBG82696.1 - 1.5e-05 24.6 0.5 3.5e-05 23.4 0.5 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 GBG82696.1 - 5.4e-05 22.9 0.1 0.0001 21.9 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GBG82696.1 - 0.00011 22.3 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 GBG82696.1 - 0.00021 20.9 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 GBG82696.1 - 0.0032 17.0 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 GBG82696.1 - 0.011 15.4 0.1 0.023 14.3 0.1 1.5 1 1 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 GBG82696.1 - 0.02 14.3 0.3 0.042 13.3 0.3 1.5 1 0 0 1 1 1 0 ATP-grasp domain RWP-RK PF02042.15 GBG82696.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 RWP-RK domain HMGL-like PF00682.19 GBG82698.1 - 8.7e-42 143.5 0.2 4.1e-40 138.0 0.0 2.4 2 0 0 2 2 2 1 HMGL-like rve PF00665.26 GBG82698.1 - 1.1e-08 35.3 0.0 6.1e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG82698.1 - 0.12 12.7 6.2 0.16 12.3 0.0 3.4 4 0 0 4 4 4 0 Retrotransposon gag protein AP1AR PF15745.5 GBG82698.1 - 5.9 6.4 7.7 18 4.9 5.2 2.4 2 0 0 2 2 2 0 AP-1 complex-associated regulatory protein Ceramidase PF05875.12 GBG82699.1 - 0.0021 17.5 0.4 0.54 9.6 0.0 2.0 2 0 0 2 2 2 2 Ceramidase DnaJ_CXXCXGXG PF00684.19 GBG82699.1 - 0.06 13.7 2.0 6.5 7.2 0.0 2.5 2 1 0 2 2 2 0 DnaJ central domain Putative_PNPOx PF01243.20 GBG82699.1 - 0.12 12.6 2.6 6.1 7.1 0.2 2.2 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DNA_pol_phi PF04931.13 GBG82699.1 - 1.2 7.2 6.9 1.3 7.0 6.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Bd3614-deam PF14439.6 GBG82699.1 - 2.7 8.1 25.7 1.8e+04 -7.3 25.7 2.8 1 1 0 1 1 1 0 Bd3614-like deaminase Cnd2 PF05786.14 GBG82699.1 - 3.7 6.1 9.1 3.6 6.1 9.1 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF2457 PF10446.9 GBG82699.1 - 6.2 5.9 7.8 6.4 5.8 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SNN_linker PF09050.10 GBG82700.1 - 1.2 9.0 3.5 25 4.7 2.2 2.6 2 0 0 2 2 2 0 Stannin unstructured linker Nudix_N_2 PF14803.6 GBG82701.1 - 0.074 13.0 1.7 0.57 10.1 0.1 3.2 3 0 0 3 3 3 0 Nudix N-terminal Acetyltransf_CG PF14542.6 GBG82703.1 - 9.9e-17 60.9 0.0 3.6e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase APC_u15 PF16636.5 GBG82703.1 - 0.17 12.3 1.9 0.23 11.9 0.1 2.1 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Glyco_transf_5 PF08323.11 GBG82704.1 - 5.4e-22 78.7 0.0 3.9e-20 72.6 0.0 2.0 1 1 0 1 1 1 1 Starch synthase catalytic domain DUF4081 PF13312.6 GBG82704.1 - 0.035 14.3 0.1 0.05 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) Glyco_transf_5 PF08323.11 GBG82705.1 - 6.5e-18 65.3 0.0 7.4e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Starch synthase catalytic domain DUF4081 PF13312.6 GBG82705.1 - 0.026 14.7 0.1 0.03 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) Retrotrans_gag PF03732.17 GBG82706.1 - 0.14 12.5 0.9 0.47 10.8 0.9 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein GRP PF07172.11 GBG82706.1 - 2.3 9.0 17.9 4.6 8.0 17.9 1.5 1 0 0 1 1 1 0 Glycine rich protein family gag-asp_proteas PF13975.6 GBG82707.1 - 1.3e-06 28.9 0.0 2.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82707.1 - 6.5e-05 23.5 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82707.1 - 0.0065 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG82707.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG82708.1 - 0.062 13.6 1.5 0.31 11.3 1.5 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein TraI PF07057.11 GBG82708.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA helicase TraI Myb_DNA-bind_4 PF13837.6 GBG82709.1 - 0.051 14.0 0.0 0.089 13.2 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG82710.1 - 0.024 15.0 0.0 0.036 14.4 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain WD40 PF00400.32 GBG82711.1 - 1.2e-09 38.6 4.6 0.13 13.2 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG82711.1 - 0.0039 17.4 0.0 6.3 7.2 0.0 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RT_RNaseH_2 PF17919.1 GBG82712.1 - 4.8e-34 116.4 0.4 1.2e-33 115.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82712.1 - 1.1e-29 102.8 0.2 3.3e-29 101.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82712.1 - 9e-06 25.7 0.1 2.1e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain CENP-Q PF13094.6 GBG82712.1 - 0.062 13.5 6.3 0.17 12.1 6.3 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RVT_1 PF00078.27 GBG82712.1 - 0.067 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG82712.1 - 0.17 11.5 5.1 3.4 7.2 0.1 2.8 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Glycos_transf_1 PF00534.20 GBG82713.1 - 1.3e-14 54.1 0.0 2.3e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG82713.1 - 2.2e-11 44.3 0.0 4.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 GBG82713.1 - 2.7e-07 30.5 0.0 5.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain RT_RNaseH PF17917.1 GBG82714.1 - 2.1e-24 85.8 0.0 5.9e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82714.1 - 1.6e-23 82.6 0.0 4.1e-23 81.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82714.1 - 2.4e-17 62.8 2.3 5.5e-17 61.6 2.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG82714.1 - 6.4e-12 45.5 0.1 1.3e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG82714.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger APG17 PF04108.12 GBG82714.1 - 0.037 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Prefoldin_3 PF13758.6 GBG82714.1 - 0.064 13.3 0.1 6.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit Na_H_Exchanger PF00999.21 GBG82715.1 - 1.4e-58 198.6 39.6 1.4e-58 198.6 39.6 1.6 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family Usp PF00582.26 GBG82715.1 - 3.5e-08 34.0 5.5 0.0036 17.8 0.0 3.5 4 0 0 4 4 4 2 Universal stress protein family RT_RNaseH PF17917.1 GBG82716.1 - 7.9e-25 87.2 0.1 2e-24 85.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82716.1 - 2.3e-23 82.1 0.0 4.6e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82716.1 - 1.4e-17 63.5 1.2 3e-17 62.5 1.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82716.1 - 1.3e-10 41.5 0.0 3.9e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG82716.1 - 0.05 13.9 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein SlyX PF04102.12 GBG82716.1 - 1.4 9.6 9.5 0.59 10.8 0.3 3.7 3 0 0 3 3 3 0 SlyX Beta_helix PF13229.6 GBG82717.1 - 7.3e-08 32.4 13.2 5.1e-07 29.7 6.8 2.2 1 1 1 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG82717.1 - 3.1e-07 30.5 31.1 1.1 9.9 0.3 7.3 7 0 0 7 7 7 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4957 PF16318.5 GBG82717.1 - 0.0022 17.9 0.0 0.014 15.4 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4957) Jnk-SapK_ap_N PF09744.9 GBG82718.1 - 0.00081 19.6 3.1 0.0022 18.2 3.1 1.8 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 GBG82718.1 - 0.13 12.3 6.2 0.36 10.9 6.2 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3292 PF11696.8 GBG82718.1 - 0.14 10.5 3.7 1.3 7.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) DUF659 PF04937.15 GBG82719.1 - 3.1e-09 36.9 0.0 6.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Nop53 PF07767.11 GBG82719.1 - 3.6 6.9 19.1 6.2 6.1 19.1 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GBG82719.1 - 6.6 4.9 17.1 11 4.1 17.1 1.3 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 GBG82719.1 - 8.1 5.4 10.4 11 4.9 10.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PTPRCAP PF15713.5 GBG82721.1 - 0.12 12.7 16.2 0.18 12.1 16.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 GBG82721.1 - 0.39 9.4 3.6 0.37 9.5 3.6 1.0 1 0 0 1 1 1 0 Presenilin Yop-YscD_cpl PF16697.5 GBG82723.1 - 0.088 13.1 3.4 21 5.5 0.1 3.2 3 0 0 3 3 3 0 Inner membrane component of T3SS, cytoplasmic domain CheD PF03975.13 GBG82723.1 - 0.16 12.1 0.9 6.5 6.9 0.0 2.2 1 1 1 2 2 2 0 CheD chemotactic sensory transduction Cgr1 PF03879.14 GBG82724.1 - 0.00025 21.4 2.7 0.00025 21.4 2.7 2.9 3 0 0 3 3 3 1 Cgr1 family DUF3236 PF11576.8 GBG82724.1 - 0.077 12.7 1.2 3.5 7.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3236) RVT_1 PF00078.27 GBG82725.1 - 0.014 14.9 0.0 0.89 9.0 0.0 2.6 1 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82726.1 - 1.5e-30 105.2 0.0 4.4e-17 62.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82726.1 - 2.1e-28 98.7 0.0 5e-28 97.4 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82726.1 - 1.4e-19 70.5 0.2 2.2e-19 69.9 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82727.1 - 7.2e-30 103.4 0.3 1.3e-29 102.5 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82727.1 - 1.6e-22 79.4 0.0 2.9e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG82727.1 - 1.2e-15 57.7 0.2 3e-15 56.4 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG82729.1 - 4.3e-16 58.8 0.0 1.4e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82729.1 - 9.9e-14 51.5 0.0 7.1e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82729.1 - 1e-08 35.1 0.1 1.1e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG82729.1 - 3.5e-05 24.3 0.0 9.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82729.1 - 0.0021 18.7 0.0 0.0055 17.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82729.1 - 0.012 15.4 0.8 0.025 14.4 0.8 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG82729.1 - 0.022 14.3 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 GBG82729.1 - 0.13 12.5 0.1 0.41 11.0 0.1 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Orf78 PF06024.12 GBG82730.1 - 8.9 6.7 10.1 22 5.4 6.6 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Sel1 PF08238.12 GBG82731.1 - 0.00064 20.3 12.8 0.015 16.0 0.1 5.7 6 0 0 6 6 6 2 Sel1 repeat gag-asp_proteas PF13975.6 GBG82732.1 - 6.9e-06 26.5 0.1 1.3e-05 25.7 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82732.1 - 0.00017 22.1 0.1 0.00035 21.2 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG82732.1 - 0.00038 20.2 0.1 0.0006 19.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG82733.1 - 5.6e-30 104.1 0.0 1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82733.1 - 1.5e-14 54.1 0.0 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82733.1 - 0.00011 21.9 0.0 0.057 13.1 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain DUF3805 PF12712.7 GBG82733.1 - 0.18 12.0 0.0 24 5.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3805) rve PF00665.26 GBG82734.1 - 6.5e-13 48.9 0.0 1.4e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG82734.1 - 2.2e-11 43.7 1.0 5.3e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG82734.1 - 1.6e-05 24.6 0.1 5.4e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_60s PF00428.19 GBG82734.1 - 0.056 14.0 4.2 0.2 12.2 4.2 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4611 PF15387.6 GBG82734.1 - 0.6 10.4 8.3 0.15 12.3 4.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-CCHC PF00098.23 GBG82735.1 - 1.3e-08 34.5 1.5 3e-08 33.3 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle Dimer_Tnp_hAT PF05699.14 GBG82735.1 - 4.1e-05 23.3 0.2 9e-05 22.2 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCHC_2 PF13696.6 GBG82735.1 - 0.00046 19.9 2.0 0.00091 19.0 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG82735.1 - 0.00052 20.5 0.0 0.0015 19.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82735.1 - 0.0089 16.7 0.1 0.033 14.8 0.1 2.1 1 1 0 1 1 1 1 Aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG82737.1 - 4.6e-07 30.1 1.9 7.9e-07 29.4 0.5 2.0 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82737.1 - 0.15 12.4 0.1 0.35 11.2 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like VCBS PF13517.6 GBG82738.1 - 0.0011 19.6 0.2 0.45 11.1 0.0 3.1 2 2 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PCI PF01399.27 GBG82739.1 - 7.2e-19 68.2 0.1 2.2e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 GBG82739.1 - 0.00057 20.0 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain RVT_1 PF00078.27 GBG82741.1 - 1.1e-30 106.8 0.1 1.8e-30 106.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82741.1 - 7.4e-12 45.2 0.0 1.1e-10 41.4 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG82741.1 - 1.4e-07 32.0 0.0 7.8e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG82741.1 - 2.3e-07 30.6 0.0 5.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG82741.1 - 2.2e-06 28.1 0.0 1.7e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG82741.1 - 0.00021 21.5 0.2 0.0013 18.9 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG82741.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG82741.1 - 0.015 15.6 0.0 0.068 13.5 0.0 2.2 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82743.1 - 3.3e-27 94.4 0.0 5.9e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82743.1 - 2.7e-26 91.9 0.0 5.1e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82743.1 - 2.5e-14 53.3 0.1 5.7e-14 52.2 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG82743.1 - 0.0018 18.1 0.2 0.12 12.3 0.0 3.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2249) DDHD PF02862.17 GBG82744.1 - 0.13 12.4 1.2 0.17 12.0 1.2 1.2 1 0 0 1 1 1 0 DDHD domain UvrC_HhH_N PF08459.11 GBG82744.1 - 0.14 12.0 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal SRP-alpha_N PF04086.13 GBG82744.1 - 0.19 11.7 16.2 0.27 11.1 16.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SAPS PF04499.15 GBG82744.1 - 0.25 10.1 3.4 0.27 10.0 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 GBG82744.1 - 0.31 10.0 3.2 0.48 9.3 3.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.6 GBG82744.1 - 0.32 9.7 9.0 0.44 9.3 9.0 1.1 1 0 0 1 1 1 0 Raftlin Mpp10 PF04006.12 GBG82744.1 - 0.37 9.2 25.4 0.59 8.5 25.4 1.2 1 0 0 1 1 1 0 Mpp10 protein SpoIIP PF07454.11 GBG82744.1 - 0.52 9.7 11.3 0.72 9.3 11.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.10 GBG82744.1 - 0.58 10.5 19.4 0.89 9.9 19.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 GBG82744.1 - 0.6 8.8 11.1 0.77 8.5 11.1 1.1 1 0 0 1 1 1 0 Presenilin CENP-N PF05238.13 GBG82744.1 - 1 8.6 7.0 3.6 6.8 7.7 1.5 2 0 0 2 2 2 0 Kinetochore protein CHL4 like Connexin PF00029.19 GBG82744.1 - 1.1 9.0 10.3 1.7 8.4 10.3 1.3 1 0 0 1 1 1 0 Connexin FGF-BP1 PF06473.12 GBG82744.1 - 1.3 8.8 14.0 0.7 9.7 12.2 1.4 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) CDC45 PF02724.14 GBG82744.1 - 2.2 6.5 20.1 3.2 5.9 20.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4770 PF15994.5 GBG82744.1 - 3.3 7.9 7.7 5.1 7.3 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) RR_TM4-6 PF06459.12 GBG82744.1 - 4.2 7.1 22.1 7 6.4 22.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 GBG82744.1 - 6.2 5.9 7.3 8.2 5.5 7.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 GBG82744.1 - 7.7 5.2 11.5 10 4.8 11.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cytomega_UL84 PF06284.11 GBG82744.1 - 8.7 4.7 13.8 14 4.0 13.8 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein AA_permease_2 PF13520.6 GBG82745.1 - 4.7e-66 223.4 32.2 6.6e-66 222.9 31.7 1.4 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 GBG82745.1 - 6.8e-42 143.7 33.7 8.6e-42 143.3 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GBG82745.1 - 5.6e-09 36.0 6.3 9.5e-09 35.2 3.4 3.1 2 0 0 2 2 2 1 C-terminus of AA_permease Spore_permease PF03845.13 GBG82745.1 - 0.00026 19.9 19.2 0.007 15.2 2.7 2.8 3 0 0 3 3 3 2 Spore germination protein EMP24_GP25L PF01105.24 GBG82746.1 - 4.6e-32 111.4 0.1 6.7e-32 110.9 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.6 GBG82746.1 - 0.0066 16.9 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Fasciclin PF02469.22 GBG82747.1 - 0.00027 21.2 0.0 0.00056 20.1 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain Pkinase PF00069.25 GBG82748.1 - 1.1e-38 133.2 0.0 1.6e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG82748.1 - 3.8e-38 131.2 0.0 1.2e-37 129.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG82748.1 - 0.0021 18.0 0.0 0.0051 16.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG82748.1 - 0.0061 15.4 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase BPD_transp_2 PF02653.16 GBG82748.1 - 0.067 12.3 0.1 2.9 7.0 0.1 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component Kdo PF06293.14 GBG82748.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIC1 PF07064.13 GBG82750.1 - 6.9e-61 205.8 0.0 2.8e-60 203.9 0.0 1.8 1 1 0 1 1 1 1 RIC1 Macoilin PF09726.9 GBG82750.1 - 0.0033 16.1 3.9 0.0033 16.1 3.9 2.0 2 0 0 2 2 2 1 Macoilin family Velvet PF11754.8 GBG82750.1 - 0.019 14.9 2.3 0.89 9.4 0.7 2.3 2 0 0 2 2 2 0 Velvet factor Zip PF02535.22 GBG82750.1 - 2.4 7.3 13.7 5.4 6.1 8.4 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter EPL1 PF10513.9 GBG82750.1 - 2.7 8.4 7.8 2.7 8.4 1.9 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like TFIIA PF03153.13 GBG82750.1 - 6.9 6.5 21.3 8.2 6.3 4.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Roc PF08477.13 GBG82751.1 - 2e-07 31.2 0.2 9.8e-07 29.0 0.0 2.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GBG82751.1 - 0.0084 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 GBG82751.1 - 0.027 13.9 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family Ras PF00071.22 GBG82751.1 - 0.085 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Ras family PLCC PF14466.6 GBG82752.1 - 0.051 13.7 0.1 8.6 6.5 0.0 3.0 2 1 1 3 3 3 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein GPS PF01825.21 GBG82752.1 - 0.087 13.4 0.5 0.32 11.6 0.5 2.0 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif NRDE-2 PF08424.10 GBG82752.1 - 0.67 9.0 5.8 0.21 10.7 0.7 2.1 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference AAA PF00004.29 GBG82753.1 - 9.8e-46 155.4 0.0 2.3e-45 154.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG82753.1 - 2e-14 53.1 0.1 4.4e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 GBG82753.1 - 1.5e-05 24.4 0.0 2.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain FtsH_ext PF06480.15 GBG82753.1 - 2.7e-05 24.5 0.0 8.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 GBG82753.1 - 7.4e-05 22.8 0.1 0.00032 20.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG82753.1 - 0.00014 21.6 0.0 0.00064 19.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GBG82753.1 - 0.00029 21.3 0.6 0.0041 17.5 0.6 3.0 1 1 0 1 1 1 1 AAA ATPase domain Peptidase_M41 PF01434.18 GBG82753.1 - 0.00057 19.8 0.1 0.001 18.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 IstB_IS21 PF01695.17 GBG82753.1 - 0.0014 18.4 0.1 0.0029 17.4 0.1 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 GBG82753.1 - 0.0015 18.9 0.1 0.083 13.2 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GBG82753.1 - 0.0021 18.5 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GBG82753.1 - 0.0031 17.6 0.0 0.0076 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GBG82753.1 - 0.0042 17.3 0.1 0.016 15.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GBG82753.1 - 0.005 16.2 0.1 0.0098 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GBG82753.1 - 0.024 15.2 0.0 0.048 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GBG82753.1 - 0.027 13.8 0.0 0.76 9.1 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 GBG82753.1 - 0.028 14.7 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GBG82753.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GBG82753.1 - 0.06 12.8 0.2 0.19 11.2 0.2 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 GBG82753.1 - 0.084 12.6 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 GBG82753.1 - 0.097 13.2 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 GBG82753.1 - 0.14 11.4 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 GBG82753.1 - 0.19 11.3 1.1 0.87 9.1 0.4 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 GBG82753.1 - 0.2 11.4 0.1 0.43 10.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 GBG82753.1 - 0.22 11.0 0.5 0.4 10.1 0.5 1.3 1 0 0 1 1 1 0 PhoH-like protein SARAF PF06682.12 GBG82755.1 - 3.7e-27 95.8 7.6 1e-15 58.3 4.8 2.0 1 1 1 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis TMEMspv1-c74-12 PF11044.8 GBG82755.1 - 0.056 13.4 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Orf78 PF06024.12 GBG82756.1 - 0.28 11.5 9.4 2.7 8.4 2.3 2.3 2 0 0 2 2 2 0 Orf78 (ac78) DUF4834 PF16118.5 GBG82756.1 - 0.91 10.5 6.1 17 6.5 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2076 PF09849.9 GBG82756.1 - 2 8.4 21.0 4.1 7.4 3.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Smg4_UPF3 PF03467.15 GBG82757.1 - 6.9e-47 159.7 0.1 1.2e-46 158.9 0.1 1.4 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_2 PF04059.12 GBG82757.1 - 0.0064 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 DUF4746 PF15928.5 GBG82759.1 - 1.5 8.2 9.9 2.1 7.7 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MAP17 PF15807.5 GBG82759.1 - 3.5 7.9 8.3 7 6.9 8.3 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Nop14 PF04147.12 GBG82759.1 - 4.5 5.4 18.4 5.7 5.0 18.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_methylase PF00145.17 GBG82760.1 - 3e-38 132.0 0.0 3.4e-34 118.7 0.0 2.6 3 0 0 3 3 3 2 C-5 cytosine-specific DNA methylase BAH PF01426.18 GBG82760.1 - 1.4e-14 54.0 0.0 8e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 BAH domain Chromo PF00385.24 GBG82760.1 - 2.1e-10 40.3 2.9 4.5e-10 39.3 2.9 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Period_C PF12114.8 GBG82760.1 - 0.078 12.6 3.4 0.2 11.2 3.4 1.7 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Metallophos PF00149.28 GBG82761.1 - 2.4e-16 60.8 3.2 5e-16 59.8 3.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GBG82761.1 - 9.3e-13 48.6 0.0 1.3e-11 44.9 0.0 2.7 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Rep_fac-A_C PF08646.10 GBG82762.1 - 1.3e-50 171.0 3.5 1.1e-47 161.4 3.6 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 GBG82762.1 - 4.6e-27 93.8 0.0 3.6e-26 90.9 0.0 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 GBG82762.1 - 4.7e-27 94.0 0.1 8.8e-27 93.1 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 GBG82762.1 - 3.9e-14 52.4 0.3 1.7e-10 40.7 0.0 3.4 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain zf-CCHC PF00098.23 GBG82762.1 - 8.1e-09 35.2 18.5 3.9e-07 29.8 2.6 3.0 3 0 0 3 3 3 2 Zinc knuckle CDC24_OB3 PF17244.2 GBG82762.1 - 0.0012 18.6 1.6 0.21 11.3 0.1 2.9 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 zf-CCHC_3 PF13917.6 GBG82762.1 - 0.32 11.0 11.8 0.025 14.5 1.7 2.9 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG82762.1 - 1.7 8.5 17.8 0.042 13.7 4.0 3.3 3 0 0 3 3 3 0 Zinc knuckle Ribosomal_L1 PF00687.21 GBG82763.1 - 1.5e-42 145.7 5.2 1.8e-42 145.4 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 GBG82763.1 - 0.71 10.0 5.1 0.39 10.8 2.9 1.8 2 1 0 2 2 2 0 Protein of unknown function Mucin2_WxxW PF13330.6 GBG82764.1 - 2.4 9.1 4.9 1.8 9.4 0.7 2.9 2 1 0 2 2 2 0 Mucin-2 protein WxxW repeating region Pyridoxal_deC PF00282.19 GBG82765.1 - 8e-109 363.8 0.0 1e-108 363.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 GBG82765.1 - 5.8e-05 22.5 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GBG82765.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Replicase PF03090.17 GBG82765.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Replicase family Dimer_Tnp_hAT PF05699.14 GBG82766.1 - 2.9e-08 33.4 0.1 6e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region C2 PF00168.30 GBG82767.1 - 6.9e-13 48.8 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain Nop14 PF04147.12 GBG82768.1 - 0.037 12.3 4.8 0.044 12.0 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_4 PF13837.6 GBG82771.1 - 1e-10 41.8 0.8 5.1e-09 36.4 0.1 2.8 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG82772.1 - 7.3e-19 68.0 0.0 2.6e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82772.1 - 7e-09 35.6 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82772.1 - 0.0038 16.9 0.0 0.0094 15.6 0.0 1.6 2 0 0 2 2 2 1 Transposase DDE domain gag-asp_proteas PF13975.6 GBG82773.1 - 0.00013 22.4 0.0 0.00034 21.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG82773.1 - 0.00086 18.9 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG82773.1 - 0.0013 19.3 0.0 0.0029 18.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG82773.1 - 0.026 14.9 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82773.1 - 0.064 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG82774.1 - 8.2e-32 110.2 0.5 2.2e-31 108.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Tyr-DNA_phospho PF06087.12 GBG82775.1 - 9e-41 140.1 0.0 2.8e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase FHA PF00498.26 GBG82775.1 - 1.3e-10 41.4 0.0 3.9e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 FHA domain HIRAN PF08797.11 GBG82775.1 - 5.6e-07 29.4 0.0 2e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 HIRAN domain Yop-YscD_cpl PF16697.5 GBG82775.1 - 6.6e-07 29.6 0.0 1.7e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PLDc_2 PF13091.6 GBG82775.1 - 0.069 13.0 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain eIF3_subunit PF08597.10 GBG82776.1 - 0.08 12.8 8.6 0.1 12.5 8.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Phage_sheath_1 PF04984.14 GBG82776.1 - 0.1 12.5 0.2 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain Matrilin_ccoil PF10393.9 GBG82776.1 - 0.18 11.7 2.8 0.97 9.3 1.9 2.6 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF3313 PF11769.8 GBG82776.1 - 0.2 11.5 4.1 0.042 13.7 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3313) PspB PF06667.12 GBG82776.1 - 2 8.5 10.7 5.6 7.1 0.9 3.5 2 2 1 3 3 3 0 Phage shock protein B Retrotrans_gag PF03732.17 GBG82777.1 - 0.0016 18.7 0.1 0.0016 18.7 0.1 2.9 3 1 0 3 3 3 1 Retrotransposon gag protein SlyX PF04102.12 GBG82777.1 - 0.049 14.2 1.7 0.049 14.2 1.7 3.3 4 1 0 4 4 4 0 SlyX Sigma70_ner PF04546.13 GBG82777.1 - 0.086 12.7 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3573 PF12097.8 GBG82777.1 - 0.11 11.3 0.5 0.16 10.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) UPF0242 PF06785.11 GBG82777.1 - 0.22 11.6 2.4 0.36 10.9 2.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus IL28A PF15177.6 GBG82777.1 - 0.48 10.2 4.8 4.9 7.0 1.7 2.7 2 1 0 2 2 2 0 Interleukin-28A Matrilin_ccoil PF10393.9 GBG82777.1 - 0.68 9.8 3.2 2 8.3 2.2 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin ATG16 PF08614.11 GBG82777.1 - 1.2 9.4 14.2 2.9 8.1 14.2 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-CCHC PF00098.23 GBG82778.1 - 1.4e-07 31.2 1.3 2.7e-07 30.4 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG82778.1 - 7.3e-07 29.7 0.0 1.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82778.1 - 0.00014 22.4 0.0 0.00042 20.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG82778.1 - 0.00099 18.9 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82778.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG82778.1 - 0.01 15.6 0.6 0.026 14.3 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.14 GBG82778.1 - 1.1 7.5 11.3 1.9 6.7 11.3 1.3 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG82779.1 - 2.7e-27 94.7 0.0 2e-15 56.6 0.0 2.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82779.1 - 1.1e-26 93.1 0.0 2.5e-26 92.0 0.0 1.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82779.1 - 1.4e-12 47.6 0.2 2.8e-12 46.6 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG82780.1 - 3.6e-11 43.3 0.1 7.4e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain CH_2 PF06294.11 GBG82781.1 - 4.8e-28 97.1 0.1 1.1e-27 96.0 0.1 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 GBG82781.1 - 3e-09 36.6 0.0 5.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain ABC_export PF16962.5 GBG82781.1 - 1.1 7.6 3.8 1.6 7.1 3.8 1.2 1 0 0 1 1 1 0 Putative ABC exporter HAUS5 PF14817.6 GBG82783.1 - 4.8e-90 303.2 0.0 6.7e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 ENTH PF01417.20 GBG82784.1 - 3e-11 43.4 0.0 7.1e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 ENTH domain VHS PF00790.19 GBG82784.1 - 3.3e-06 27.0 0.0 0.00074 19.4 0.0 2.2 2 0 0 2 2 2 2 VHS domain ANTH PF07651.16 GBG82784.1 - 0.00076 18.5 0.0 0.4 9.6 0.0 2.1 2 0 0 2 2 2 2 ANTH domain Ras PF00071.22 GBG82785.1 - 7.3e-63 211.0 0.3 8.6e-63 210.8 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG82785.1 - 8.2e-35 119.6 0.1 1.4e-34 118.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG82785.1 - 5.6e-12 45.5 0.1 7.8e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GBG82785.1 - 4.3e-07 30.0 0.0 8.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG82785.1 - 8.3e-05 22.5 0.3 0.024 14.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GBG82785.1 - 0.0002 21.0 0.1 0.0011 18.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GBG82785.1 - 0.00063 19.3 0.1 0.0017 17.9 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 GBG82785.1 - 0.0015 18.8 0.2 0.036 14.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG82785.1 - 0.014 15.8 0.2 0.029 14.8 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 GBG82785.1 - 0.016 15.7 0.1 0.024 15.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 GBG82785.1 - 0.029 13.7 0.1 0.043 13.2 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GBG82785.1 - 0.031 13.7 0.0 0.051 13.0 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 GBG82785.1 - 0.033 13.9 0.0 0.078 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GBG82785.1 - 0.043 13.8 0.1 0.12 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 GBG82785.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 GBG82785.1 - 0.11 11.9 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 GBG82785.1 - 0.13 12.0 0.1 0.39 10.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Dimer_Tnp_hAT PF05699.14 GBG82786.1 - 6.9e-07 29.0 0.0 1.7e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HATPase_c PF02518.26 GBG82790.1 - 4.4e-25 88.4 0.1 7.9e-18 65.0 0.1 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GBG82790.1 - 1e-17 64.3 0.1 2e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GBG82790.1 - 3.6e-17 62.2 0.2 1.3e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF659 PF04937.15 GBG82790.1 - 8.9e-16 58.1 0.0 1.8e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG82790.1 - 6.4e-08 32.3 3.1 4.7e-07 29.5 0.3 3.3 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region PAS_7 PF12860.7 GBG82790.1 - 0.0004 20.5 0.0 0.0019 18.4 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 GBG82790.1 - 0.087 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 PAS domain eIF3_subunit PF08597.10 GBG82790.1 - 0.19 11.6 8.3 0.044 13.7 3.5 2.3 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit HATPase_c_3 PF13589.6 GBG82790.1 - 3.1 7.6 4.9 3.4 7.5 0.1 2.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Integrase_H2C2 PF17921.1 GBG82791.1 - 1.2e-15 57.4 0.2 4.3e-15 55.6 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG82791.1 - 7.4e-11 42.3 0.3 2e-10 40.9 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82791.1 - 3.5e-05 23.8 0.0 7.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG82791.1 - 6e-05 22.9 0.2 0.00022 21.1 0.0 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG82791.1 - 0.0021 18.3 0.0 0.0058 16.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF4187 PF13821.6 GBG82791.1 - 0.0027 17.4 0.4 0.0087 15.8 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG82791.1 - 0.0039 17.4 0.1 0.013 15.7 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG82791.1 - 0.005 17.0 0.1 0.016 15.4 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG82792.1 - 0.0047 16.9 2.0 0.011 15.7 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle TFIIA PF03153.13 GBG82792.1 - 0.78 9.7 6.4 0.87 9.5 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rrn6 PF10214.9 GBG82792.1 - 0.83 8.1 11.2 1.3 7.5 11.2 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FlxA PF14282.6 GBG82793.1 - 0.035 14.1 5.5 0.05 13.6 0.1 2.2 1 1 1 2 2 2 0 FlxA-like protein MFS_MOT1 PF16983.5 GBG82793.1 - 0.056 13.8 0.2 0.095 13.1 0.2 1.4 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily DUF1542 PF07564.11 GBG82793.1 - 1.6 8.9 5.2 0.26 11.4 1.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) ABC_tran_CTD PF16326.5 GBG82793.1 - 2.5 8.4 5.1 2.8 8.2 0.6 2.8 2 1 0 3 3 3 0 ABC transporter C-terminal domain Abhydrolase_1 PF00561.20 GBG82794.1 - 1.6e-17 64.0 0.5 1.1e-16 61.2 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG82794.1 - 7.5e-16 59.4 0.8 9.3e-16 59.1 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG82794.1 - 8.6e-09 35.0 0.5 1.8e-08 33.9 0.5 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 GBG82794.1 - 0.086 11.5 0.0 0.38 9.4 0.0 1.7 1 1 1 2 2 2 0 Ndr family Esterase PF00756.20 GBG82794.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 GBG82794.1 - 0.17 11.7 2.3 9 6.0 0.1 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase gag-asp_proteas PF13975.6 GBG82795.1 - 0.0011 19.5 0.0 0.0027 18.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82795.1 - 0.0061 17.2 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG82795.1 - 4.2 8.1 13.2 1.2 9.8 0.1 3.8 3 0 0 3 3 3 0 SlyX CDC45 PF02724.14 GBG82795.1 - 8.6 4.5 7.5 16 3.6 7.5 1.4 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG82796.1 - 3.2e-16 59.2 0.0 7.6e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82796.1 - 1.3e-14 54.3 0.0 4e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82798.1 - 1.1e-25 90.4 0.0 2e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG82798.1 - 4.5e-08 32.9 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82798.1 - 1.6e-07 31.8 0.0 5.7e-07 30.1 0.0 2.0 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82798.1 - 5.4e-06 26.9 0.1 1.6e-05 25.4 0.0 1.8 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82798.1 - 0.004 16.9 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG82798.1 - 0.02 15.5 0.5 0.02 15.5 0.5 4.6 4 1 1 5 5 3 0 SlyX Retrotrans_gag PF03732.17 GBG82798.1 - 0.07 13.4 0.1 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2730 PF10805.8 GBG82798.1 - 0.094 12.8 0.3 0.31 11.1 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) AMP-binding_C_2 PF14535.6 GBG82798.1 - 0.15 12.4 0.2 0.71 10.2 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain NPV_P10 PF05531.12 GBG82798.1 - 0.47 11.0 1.9 1.8 9.1 0.7 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DDRGK PF09756.9 GBG82798.1 - 0.97 9.0 9.3 2.2 7.8 9.3 1.5 1 0 0 1 1 1 0 DDRGK domain PTS_IIA PF02255.16 GBG82798.1 - 1.1 9.3 7.4 1.6 8.8 3.4 2.8 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit BTB PF00651.31 GBG82799.1 - 5.7e-12 45.9 0.0 2.8e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Retrotrans_gag PF03732.17 GBG82799.1 - 1.6 9.0 8.0 0.11 12.8 0.3 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein Ccdc124 PF06244.12 GBG82799.1 - 8.4 7.0 15.1 1.3 9.6 7.9 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 Glycolytic PF00274.19 GBG82800.1 - 2.1e-172 572.7 0.0 2.3e-172 572.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Myb_DNA-bind_4 PF13837.6 GBG82801.1 - 2.9e-08 34.0 0.5 5.5e-08 33.1 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG82802.1 - 0.00025 21.0 1.2 0.00048 20.1 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle MPM1 PF17234.2 GBG82802.1 - 1.4 9.2 8.5 2.1 8.6 8.0 1.6 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DDA1 PF10172.9 GBG82803.1 - 6.9e-13 48.7 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase SAP PF02037.27 GBG82803.1 - 3.9e-10 39.2 1.8 3.9e-10 39.2 1.8 2.1 2 0 0 2 2 2 1 SAP domain Ish1 PF10281.9 GBG82803.1 - 0.011 16.0 0.2 0.022 15.0 0.2 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein HeH PF12949.7 GBG82803.1 - 0.036 13.8 0.4 0.082 12.6 0.4 1.6 1 1 0 1 1 1 0 HeH/LEM domain RT_RNaseH PF17917.1 GBG82804.1 - 5.5e-26 90.9 0.0 1.1e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82804.1 - 9.1e-20 70.6 0.0 2e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG82804.1 - 0.00038 20.3 0.9 0.0024 17.8 0.0 2.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG82804.1 - 0.089 12.5 0.4 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-CCHC PF00098.23 GBG82804.1 - 0.77 10.0 3.0 1.6 8.9 3.0 1.6 1 0 0 1 1 1 0 Zinc knuckle Cellulose_synt PF03552.14 GBG82805.1 - 3e-231 769.8 0.0 8.3e-231 768.4 0.0 1.7 1 1 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.6 GBG82805.1 - 1.1e-12 47.8 8.0 2.7e-12 46.6 8.0 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 GBG82805.1 - 2.3e-06 27.3 10.9 4.8e-06 26.3 10.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Homeobox_KN PF05920.11 GBG82806.1 - 3.8e-16 58.7 0.8 1.7e-15 56.7 0.8 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 GBG82806.1 - 2.4e-06 27.3 0.7 2.4e-06 27.3 0.7 1.8 2 0 0 2 2 2 1 Homeodomain ELK PF03789.13 GBG82806.1 - 0.0083 16.2 1.0 0.015 15.4 1.0 1.5 1 0 0 1 1 1 1 ELK domain CENP-K PF11802.8 GBG82808.1 - 0.027 14.0 2.2 0.04 13.5 2.2 1.3 1 0 0 1 1 1 0 Centromere-associated protein K TMEM247 PF15444.6 GBG82808.1 - 0.17 11.9 0.1 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 247 Macoilin PF09726.9 GBG82808.1 - 0.28 9.7 5.2 0.045 12.3 0.5 1.9 2 0 0 2 2 2 0 Macoilin family Caudo_TAP PF02413.17 GBG82808.1 - 1.6 8.9 10.9 1.5 8.9 2.5 2.7 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK ABATE PF07336.11 GBG82808.1 - 1.8 9.2 16.3 7.1 7.3 7.3 2.5 1 1 1 2 2 2 0 Putative stress-induced transcription regulator MscS_TM PF12794.7 GBG82808.1 - 9.7 4.9 13.1 0.094 11.6 0.3 2.1 1 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 RVT_1 PF00078.27 GBG82809.1 - 3.1e-36 125.0 0.1 5e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82809.1 - 7.1e-22 77.3 0.0 1.9e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82809.1 - 9.5e-11 41.9 0.0 2.5e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG82809.1 - 1.8e-07 31.0 0.0 4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82809.1 - 1.3e-06 29.0 0.0 2.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82809.1 - 1.2e-05 25.8 0.0 2.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82809.1 - 0.0073 16.1 0.0 0.031 14.1 0.0 1.9 1 1 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG82809.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG82812.1 - 2.8e-28 99.0 0.1 5.3e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG82812.1 - 3.5e-09 36.5 0.0 1.2e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82812.1 - 1.4e-06 28.9 0.0 4.1e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82812.1 - 1.8e-06 28.4 0.0 4.9e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82812.1 - 0.11 12.3 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease PTS_EIIA_2 PF00359.22 GBG82812.1 - 0.17 11.8 0.1 3.9 7.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 RT_RNaseH_2 PF17919.1 GBG82813.1 - 3.1e-28 97.7 0.0 5.9e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82813.1 - 5.1e-27 94.2 0.0 9.3e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82813.1 - 0.035 13.6 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 GBG82813.1 - 2.9 6.6 7.3 4.2 6.0 7.3 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG82813.1 - 9.3 4.4 19.0 13 3.9 19.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_tranf_2_3 PF13641.6 GBG82814.1 - 2.9e-25 89.5 0.1 4.1e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG82814.1 - 1.5e-21 77.2 5.6 3.4e-21 76.0 5.6 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG82814.1 - 8.9e-14 51.7 0.0 1.4e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF3473 PF11959.8 GBG82814.1 - 0.059 13.4 0.9 0.25 11.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3473) Glyco_tranf_2_3 PF13641.6 GBG82815.1 - 2.5e-25 89.7 0.1 5.9e-25 88.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG82815.1 - 2.5e-21 76.5 5.6 4.9e-21 75.5 5.6 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG82815.1 - 9.8e-14 51.5 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cwf_Cwc_15 PF04889.12 GBG82815.1 - 0.00064 19.5 2.1 0.0014 18.4 0.2 1.9 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 GBG82815.1 - 1.2 7.2 4.6 1.9 6.5 4.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 GBG82815.1 - 1.6 8.4 6.5 0.22 11.2 1.1 2.2 2 0 0 2 2 2 0 FAM176 family Integrase_H2C2 PF17921.1 GBG82816.1 - 2.1e-15 56.6 0.1 4.4e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG82816.1 - 3.9e-07 30.5 0.0 8.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82816.1 - 0.00092 19.8 0.0 0.0023 18.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG82816.1 - 0.015 15.5 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG82816.1 - 0.034 13.9 0.6 0.06 13.1 0.6 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG82816.1 - 0.16 12.3 0.0 0.47 10.8 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG82817.1 - 3.6e-05 23.6 2.2 8.1e-05 22.5 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle EF-hand_like PF09279.11 GBG82817.1 - 0.033 14.7 1.6 0.033 14.7 1.6 1.7 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like LMBR1 PF04791.16 GBG82817.1 - 0.12 11.3 2.1 0.12 11.3 2.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-CCHC_4 PF14392.6 GBG82817.1 - 0.17 11.7 0.8 0.37 10.6 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle PI3K_1B_p101 PF10486.9 GBG82817.1 - 0.32 8.7 7.0 0.42 8.3 7.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit HalX PF08663.10 GBG82817.1 - 1.6 9.1 21.6 0.094 13.0 14.3 2.5 2 1 0 2 2 2 0 HalX domain V_ATPase_I PF01496.19 GBG82817.1 - 3.3 5.5 7.4 3.9 5.3 7.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family P5-ATPase PF12409.8 GBG82817.1 - 4.4 7.4 5.2 0.77 9.9 1.1 1.7 2 0 0 2 2 2 0 P5-type ATPase cation transporter DUF2207 PF09972.9 GBG82817.1 - 5.7 5.6 7.0 8 5.1 7.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-CCHC_2 PF13696.6 GBG82817.1 - 6.4 6.7 5.3 3 7.7 3.0 1.7 2 0 0 2 2 2 0 Zinc knuckle Glyco_tranf_2_3 PF13641.6 GBG82818.1 - 1e-21 77.9 0.0 1.5e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG82818.1 - 3.2e-20 72.9 7.3 3.2e-20 72.9 7.3 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG82818.1 - 7.1e-13 48.7 0.0 2e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 RT_RNaseH_2 PF17919.1 GBG82819.1 - 5e-30 103.5 0.0 2.9e-15 56.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82819.1 - 4.6e-29 100.8 0.0 9.5e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82819.1 - 2.1e-27 96.1 0.1 3.6e-27 95.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82819.1 - 2.5e-15 56.3 0.1 8.6e-15 54.6 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG82819.1 - 2.7e-11 43.2 0.0 6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG82819.1 - 3.5e-11 43.3 0.0 1.2e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82819.1 - 0.00015 21.9 0.1 0.00047 20.3 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF1308 PF07000.11 GBG82820.1 - 1.3e-35 122.7 0.5 1e-34 119.8 0.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 GBG82820.1 - 0.00027 20.3 0.0 0.00027 20.3 0.0 3.0 3 0 0 3 3 3 1 Family of unknown function (DUF5614) Thiol_cytolys_C PF17440.2 GBG82820.1 - 8.3 6.7 6.1 2 8.6 0.3 2.4 2 0 0 2 2 2 0 Thiol-activated cytolysin beta sandwich domain RVT_1 PF00078.27 GBG82821.1 - 1.8e-32 112.7 0.0 3.2e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) eIF3g PF12353.8 GBG82821.1 - 0.051 14.0 0.6 0.12 12.7 0.6 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 GBG82821.1 - 0.15 12.0 1.4 0.32 11.0 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Spt5-NGN PF03439.13 GBG82822.1 - 0.15 12.0 0.3 1 9.3 0.0 2.5 3 0 0 3 3 3 0 Early transcription elongation factor of RNA pol II, NGN section KN17_SH3 PF18131.1 GBG82823.1 - 6.9e-20 70.9 8.1 1.1e-18 67.1 5.9 2.2 2 0 0 2 2 2 2 KN17 SH3-like C-terminal domain KOW PF00467.29 GBG82823.1 - 0.038 13.9 0.1 0.038 13.9 0.1 3.4 4 0 0 4 4 4 0 KOW motif DUF1412 PF07203.11 GBG82823.1 - 0.05 13.8 0.3 5 7.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1412) MFS_1 PF07690.16 GBG82824.1 - 2.9e-23 82.4 15.3 2.9e-23 82.4 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GBG82824.1 - 0.021 13.1 0.1 0.021 13.1 0.1 1.9 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Myc_N PF01056.18 GBG82825.1 - 0.0076 16.2 0.2 0.076 12.9 0.1 2.0 2 0 0 2 2 2 1 Myc amino-terminal region BSP_II PF05432.11 GBG82825.1 - 0.032 13.9 10.2 0.24 11.0 5.7 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF3682 PF12446.8 GBG82825.1 - 0.041 14.4 5.3 0.091 13.2 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Phage_Gp23 PF10669.9 GBG82825.1 - 0.65 10.3 5.1 1.3 9.4 5.1 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Pox_Ag35 PF03286.14 GBG82825.1 - 0.67 9.7 6.2 2 8.1 1.7 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nop14 PF04147.12 GBG82826.1 - 0.26 9.5 7.3 0.26 9.4 7.3 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG82826.1 - 2.5 7.4 9.4 3 7.1 9.4 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GBG82826.1 - 2.8 7.6 8.2 3.9 7.1 8.2 1.2 1 0 0 1 1 1 0 FAM176 family Tfb4 PF03850.14 GBG82827.1 - 4.9e-81 272.2 0.0 1.3e-80 270.8 0.0 1.7 1 1 0 1 1 1 1 Transcription factor Tfb4 LINES_N PF14694.6 GBG82827.1 - 4.2e-11 42.9 1.8 7.6e-11 42.1 1.8 1.4 1 0 0 1 1 1 1 Lines N-terminus Tcf25 PF04910.14 GBG82828.1 - 1.6e-79 267.5 0.0 2.5e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_7 PF13176.6 GBG82828.1 - 0.00046 20.0 0.2 0.0037 17.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG82828.1 - 0.045 13.6 0.3 0.19 11.7 0.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG82828.1 - 0.046 13.9 0.4 0.14 12.4 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG82828.1 - 0.054 13.6 0.6 0.9 9.7 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG82828.1 - 0.12 12.6 2.7 0.23 11.8 1.2 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat CBM_14 PF01607.24 GBG82828.1 - 0.18 12.0 0.8 0.39 10.9 0.8 1.5 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain Spt20 PF12090.8 GBG82828.1 - 3.8 7.0 14.0 6.9 6.2 14.0 1.3 1 0 0 1 1 1 0 Spt20 family NARP1 PF12569.8 GBG82828.1 - 6.8 5.5 5.5 25 3.6 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 2Fe-2S_thioredx PF01257.19 GBG82829.1 - 7.6e-56 188.0 0.0 9.9e-56 187.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.11 GBG82829.1 - 0.089 13.2 0.0 0.21 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) Sacchrp_dh_NADP PF03435.18 GBG82830.1 - 0.07 13.4 0.2 0.2 11.9 0.2 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TEX19 PF15553.6 GBG82830.1 - 3.1 7.8 5.1 2.2 8.2 2.8 1.9 1 1 1 2 2 2 0 Testis-expressed protein 19 TPR_1 PF00515.28 GBG82831.1 - 1.5e-28 97.4 0.1 5.1e-05 22.9 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 GBG82831.1 - 5e-28 94.9 3.3 0.0013 18.7 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 GBG82831.1 - 1.7e-17 63.7 0.8 2.5e-07 31.2 0.0 4.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 GBG82831.1 - 2.4e-17 62.0 2.3 0.021 15.2 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 GBG82831.1 - 3.7e-17 61.7 0.2 1.2e-05 24.8 0.0 5.5 5 1 1 6 6 6 4 TPR repeat TPR_9 PF13371.6 GBG82831.1 - 3.9e-16 59.0 7.1 0.00013 22.1 0.2 4.4 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG82831.1 - 8.7e-16 56.7 0.2 0.12 12.6 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 GBG82831.1 - 5.3e-13 48.6 5.9 0.019 15.7 0.2 6.1 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 GBG82831.1 - 7.1e-08 32.8 2.8 0.035 14.6 0.1 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GBG82831.1 - 2.7e-06 27.6 9.6 0.032 14.5 0.1 5.4 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 GBG82831.1 - 5.4e-06 26.7 1.7 2.8 8.8 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG82831.1 - 8.1e-06 25.5 3.9 0.52 10.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG82831.1 - 3.6e-05 23.9 0.6 4 7.7 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 GBG82831.1 - 0.0005 20.1 1.7 0.041 14.0 0.0 4.4 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat COPI_C PF06957.11 GBG82831.1 - 0.016 14.0 0.1 0.043 12.6 0.1 1.7 1 1 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus HTH_Tnp_1 PF01527.20 GBG82831.1 - 0.07 13.5 1.7 2.2 8.7 0.3 2.5 2 0 0 2 2 2 0 Transposase Methyltransf_25 PF13649.6 GBG82831.1 - 0.073 13.8 0.1 0.65 10.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain BTAD PF03704.17 GBG82831.1 - 3.3 8.1 8.9 6 7.3 3.6 3.5 2 2 0 2 2 2 0 Bacterial transcriptional activator domain TPR_1 PF00515.28 GBG82832.1 - 5.4e-28 95.6 0.1 9e-05 22.1 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 GBG82832.1 - 5.7e-27 91.6 1.0 0.0012 18.8 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 GBG82832.1 - 1.1e-16 61.1 0.6 2.3e-07 31.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GBG82832.1 - 1.4e-16 59.6 0.5 0.02 15.3 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 GBG82832.1 - 1.7e-16 59.6 0.1 1.2e-05 24.9 0.0 4.7 4 1 1 5 5 5 4 TPR repeat TPR_8 PF13181.6 GBG82832.1 - 2e-15 55.6 0.1 0.12 12.7 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 GBG82832.1 - 1.6e-13 50.6 4.6 0.00022 21.3 0.3 4.4 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GBG82832.1 - 1.4e-12 47.3 2.7 0.018 15.8 0.2 5.2 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 GBG82832.1 - 6.3e-08 33.0 2.8 0.033 14.7 0.1 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GBG82832.1 - 1.5e-07 31.6 7.6 0.03 14.6 0.1 5.3 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 GBG82832.1 - 9.3e-06 25.4 4.3 0.49 10.3 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG82832.1 - 1.5e-05 25.3 1.6 2.6 8.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GBG82832.1 - 0.00045 20.2 1.7 0.038 14.1 0.0 4.4 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 GBG82832.1 - 0.00048 20.3 0.0 3.9 7.8 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 COPI_C PF06957.11 GBG82832.1 - 0.014 14.2 0.1 0.037 12.8 0.1 1.8 1 1 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus HTH_Tnp_1 PF01527.20 GBG82832.1 - 0.062 13.6 1.7 2 8.8 0.3 2.5 2 0 0 2 2 2 0 Transposase Methyltransf_25 PF13649.6 GBG82832.1 - 0.069 13.9 0.1 0.59 10.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF3808 PF10300.9 GBG82832.1 - 0.084 11.6 0.1 7.6 5.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) BTAD PF03704.17 GBG82832.1 - 0.73 10.3 6.8 5.2 7.5 3.6 3.4 2 1 0 2 2 2 0 Bacterial transcriptional activator domain RT_RNaseH_2 PF17919.1 GBG82833.1 - 1.2e-32 111.9 0.1 6e-32 109.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82833.1 - 7.2e-31 107.4 0.1 1.2e-30 106.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82833.1 - 2.4e-29 101.7 0.1 7.3e-29 100.1 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82833.1 - 1.8e-11 44.0 0.1 4.2e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG82833.1 - 4.7e-06 27.1 0.1 5.2e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82833.1 - 0.00054 20.6 0.0 0.0073 16.9 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG82833.1 - 0.008 16.4 0.1 0.023 15.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG82833.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.12 GBG82833.1 - 0.023 14.5 0.0 0.023 14.5 0.0 1.8 2 0 0 2 2 2 0 Putative peptidase (DUF1758) TPR_1 PF00515.28 GBG82834.1 - 1.7e-09 37.1 0.3 0.00014 21.5 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG82834.1 - 3.9e-08 32.8 1.3 0.00044 20.2 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG82834.1 - 1.1e-07 31.4 0.0 2.2e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 GBG82834.1 - 1.4e-07 31.2 0.3 0.00023 21.1 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG82834.1 - 1.1e-05 25.5 0.1 0.00011 22.4 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG82834.1 - 7e-05 23.0 1.1 0.0015 18.8 0.2 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG82834.1 - 0.00014 22.4 0.2 0.21 12.3 0.4 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG82834.1 - 0.00029 21.4 0.4 0.14 13.0 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG82834.1 - 0.00069 19.5 0.4 0.013 15.5 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG82834.1 - 0.00089 19.7 0.1 0.0015 19.0 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 GBG82834.1 - 0.0017 18.9 0.4 0.064 13.9 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GBG82834.1 - 0.0074 16.4 1.8 0.044 13.9 0.5 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 GBG82834.1 - 0.067 12.4 0.2 0.12 11.6 0.2 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF371 PF04027.13 GBG82834.1 - 0.17 11.9 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF371) RT_RNaseH_2 PF17919.1 GBG82836.1 - 1.6e-21 76.2 0.0 1.9e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82836.1 - 1.8e-19 70.1 0.1 8.6e-18 64.7 0.1 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82836.1 - 6.2e-15 55.0 2.8 6.8e-15 54.9 0.0 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG82836.1 - 1.6e-12 47.6 0.0 3.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG82836.1 - 3.8e-10 39.5 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG82836.1 - 9e-10 38.8 0.1 5.3e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG82836.1 - 2.2e-05 24.6 0.0 4.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger eIF-1a PF01176.19 GBG82837.1 - 0.0039 17.0 0.0 0.016 15.0 0.1 2.0 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 CCD48 PF15799.5 GBG82837.1 - 0.013 13.9 3.2 0.019 13.3 3.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 CCDC85 PF10226.9 GBG82837.1 - 0.019 14.7 0.4 0.045 13.4 0.4 1.6 1 0 0 1 1 1 0 CCDC85 family DUF2385 PF09539.10 GBG82837.1 - 0.053 14.0 0.2 1.4 9.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Chromo PF00385.24 GBG82837.1 - 0.096 12.6 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DivIC PF04977.15 GBG82837.1 - 0.16 11.8 1.4 0.52 10.1 1.4 1.8 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 GBG82837.1 - 0.2 11.8 7.8 0.065 13.3 4.0 2.1 2 0 0 2 2 2 0 Basic region leucine zipper HALZ PF02183.18 GBG82837.1 - 0.29 11.4 2.5 0.84 9.9 2.5 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GBG82837.1 - 0.8 9.9 5.7 0.34 11.0 1.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 GBG82837.1 - 1.5 9.3 7.7 0.59 10.6 3.9 2.3 2 0 0 2 2 2 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 GBG82837.1 - 2.4 8.4 6.1 1.8 8.8 2.2 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain TTL PF03133.15 GBG82839.1 - 3.5e-18 65.8 0.1 5e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GBG82839.1 - 7e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 GBG82839.1 - 0.023 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp TTL PF03133.15 GBG82840.1 - 5.9e-41 140.5 0.0 1.5e-29 103.0 0.0 2.3 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family TTL PF03133.15 GBG82841.1 - 4.3e-41 141.0 0.0 1.2e-29 103.4 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family DUF4045 PF13254.6 GBG82842.1 - 1.9 8.1 25.1 3.1 7.4 25.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SDA1 PF05285.12 GBG82843.1 - 0.0078 15.7 35.7 0.01 15.3 35.7 1.1 1 0 0 1 1 1 1 SDA1 SpoIIIAH PF12685.7 GBG82843.1 - 0.026 14.4 11.4 0.035 13.9 11.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIF_alpha PF05793.12 GBG82843.1 - 0.099 11.2 32.4 0.13 10.8 32.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GBG82843.1 - 0.12 10.6 27.2 0.17 10.2 27.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG82843.1 - 0.16 10.2 36.1 0.2 9.8 36.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG82843.1 - 0.19 11.0 32.1 0.24 10.7 32.1 1.1 1 0 0 1 1 1 0 BUD22 DDHD PF02862.17 GBG82843.1 - 0.6 10.2 3.8 0.8 9.8 3.8 1.3 1 0 0 1 1 1 0 DDHD domain DUF5427 PF10310.9 GBG82843.1 - 0.63 8.9 17.8 0.83 8.5 17.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4045 PF13254.6 GBG82843.1 - 0.84 9.2 15.0 1.1 8.9 15.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Mpp10 PF04006.12 GBG82843.1 - 1 7.7 34.6 1.5 7.1 34.6 1.2 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 GBG82843.1 - 1.5 7.6 11.8 1.6 7.4 11.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 GBG82843.1 - 4.7 6.3 10.1 5.7 6.1 10.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GBG82843.1 - 4.8 5.8 18.1 6.2 5.5 18.1 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 GBG82843.1 - 5 6.0 10.8 6.8 5.6 10.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SURF2 PF05477.11 GBG82843.1 - 5.8 6.5 18.0 9 5.9 18.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) FRQ PF09421.10 GBG82843.1 - 6.6 4.6 13.4 8.5 4.3 13.4 1.1 1 0 0 1 1 1 0 Frequency clock protein PPP4R2 PF09184.11 GBG82843.1 - 8.6 5.9 31.4 14 5.2 31.4 1.3 1 0 0 1 1 1 0 PPP4R2 SpoIIP PF07454.11 GBG82843.1 - 9.1 5.6 17.1 15 5.0 17.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 GBG82843.1 - 9.7 5.9 26.2 16 5.2 26.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA PF00004.29 GBG82844.1 - 1.9e-57 193.4 0.0 1.4e-45 155.0 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG82844.1 - 1.5e-12 48.2 0.9 0.00029 21.3 0.0 4.3 4 1 1 5 5 4 2 AAA ATPase domain AAA_lid_3 PF17862.1 GBG82844.1 - 3.3e-12 46.0 0.6 1.5e-07 31.1 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_22 PF13401.6 GBG82844.1 - 2.1e-08 34.5 0.4 0.0092 16.3 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 GBG82844.1 - 4.2e-07 30.0 0.2 0.039 14.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG82844.1 - 7.8e-07 29.0 0.0 0.00056 19.7 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GBG82844.1 - 8.3e-07 29.6 0.0 0.045 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 GBG82844.1 - 2.6e-06 27.4 0.0 0.087 12.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GBG82844.1 - 9.3e-05 22.6 0.0 0.18 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 GBG82844.1 - 0.00035 20.5 0.0 0.065 13.1 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain IstB_IS21 PF01695.17 GBG82844.1 - 0.00042 20.1 0.0 0.01 15.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 GBG82844.1 - 0.00042 20.7 0.0 0.07 13.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 GBG82844.1 - 0.0015 17.9 0.1 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_6 PF12774.7 GBG82844.1 - 0.002 17.1 0.0 0.042 12.8 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 GBG82844.1 - 0.0021 17.6 0.0 0.077 12.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 GBG82844.1 - 0.0025 17.0 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 GBG82844.1 - 0.0027 17.3 0.4 0.022 14.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GBG82844.1 - 0.0042 17.2 0.0 0.15 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ATPase PF06745.13 GBG82844.1 - 0.0043 16.4 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 KaiC Sigma54_activat PF00158.26 GBG82844.1 - 0.0048 16.6 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 GBG82844.1 - 0.0054 16.1 0.1 0.061 12.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GBG82844.1 - 0.0069 16.6 0.3 0.3 11.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 GBG82844.1 - 0.0069 15.5 0.0 2.4 7.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.6 GBG82844.1 - 0.0086 16.1 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 GBG82844.1 - 0.0098 15.6 0.1 3.4 7.4 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase AAA_24 PF13479.6 GBG82844.1 - 0.022 14.5 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 GBG82844.1 - 0.045 12.8 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 GBG82844.1 - 0.083 12.7 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GBG82844.1 - 0.09 12.5 0.6 8.2 6.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GBG82844.1 - 0.095 12.1 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein TRH PF05438.12 GBG82844.1 - 0.33 10.7 3.5 0.46 10.2 2.1 1.9 2 0 0 2 2 2 0 Thyrotropin-releasing hormone (TRH) Integrase_H2C2 PF17921.1 GBG82847.1 - 1.1e-15 57.4 0.1 2.8e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82847.1 - 3.1e-05 24.1 0.0 6.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82847.1 - 0.0019 18.4 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG82848.1 - 1e-15 57.6 0.1 2.3e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82848.1 - 2.7e-05 24.3 0.0 5.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG82848.1 - 0.0017 18.5 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG82849.1 - 4.8e-05 23.2 2.0 8.4e-05 22.5 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF2576 PF10845.8 GBG82849.1 - 0.68 9.6 2.5 4.1 7.1 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2576) HAD_2 PF13419.6 GBG82850.1 - 1.8e-15 57.5 0.0 5e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GBG82850.1 - 5.7e-11 43.1 0.0 1.2e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG82850.1 - 0.00018 21.5 0.0 0.00042 20.3 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like RT_RNaseH PF17917.1 GBG82850.1 - 0.00066 19.9 0.2 0.0016 18.7 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase IL32 PF15225.6 GBG82850.1 - 0.022 15.1 0.4 0.23 11.8 0.1 2.6 2 0 0 2 2 2 0 Interleukin 32 Retrotrans_gag PF03732.17 GBG82850.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein HHH_9 PF17674.1 GBG82850.1 - 3.3 8.7 4.8 53 4.8 1.3 3.1 2 1 1 3 3 3 0 HHH domain Sedlin_N PF04628.13 GBG82852.1 - 2.8e-20 72.8 0.1 3.7e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region TMEM171 PF15471.6 GBG82852.1 - 8.3 5.3 11.8 11 4.9 11.8 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Glucan_synthase PF02364.15 GBG82853.1 - 2.9e-38 131.6 0.3 5.6e-38 130.7 0.3 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 GBG82853.1 - 1.4e-34 119.2 0.1 1.4e-34 119.2 0.1 2.9 3 0 0 3 3 3 1 1,3-beta-glucan synthase subunit FKS1, domain-1 gag-asp_proteas PF13975.6 GBG82853.1 - 0.0082 16.7 0.0 0.024 15.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82853.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Cytochrom_B_C PF00032.17 GBG82853.1 - 1.1 9.6 7.2 10 6.5 2.5 3.4 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Glucan_synthase PF02364.15 GBG82854.1 - 8.6e-160 533.6 14.8 7.7e-148 494.1 5.3 2.3 2 0 0 2 2 2 2 1,3-beta-glucan synthase component DUF659 PF04937.15 GBG82855.1 - 4.4e-10 39.6 0.0 1.3e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG82855.1 - 0.039 13.7 1.0 0.099 12.4 0.3 2.1 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG82856.1 - 3.5e-10 39.9 0.0 8.8e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG82856.1 - 0.023 14.4 0.9 0.069 12.9 0.3 2.1 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region TFIIA PF03153.13 GBG82856.1 - 0.21 11.6 61.7 0.027 14.5 52.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 GBG82856.1 - 7.7 4.7 46.7 12 4.1 46.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DnaJ_C PF01556.18 GBG82857.1 - 1.2e-43 148.7 0.3 1.9e-41 141.6 0.2 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.31 GBG82857.1 - 4.7e-23 81.1 1.5 1.1e-22 79.9 1.5 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GBG82857.1 - 7.5e-15 55.1 20.0 1.6e-14 54.0 20.0 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 GBG82857.1 - 0.24 11.4 9.0 4 7.5 0.7 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 GBG82857.1 - 0.37 10.8 15.0 0.061 13.3 1.5 2.8 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 GBG82857.1 - 0.51 10.4 9.3 1.5 8.8 9.3 1.8 1 1 0 1 1 1 0 zinc-ribbons zf-RING_10 PF16685.5 GBG82857.1 - 6.2 7.0 9.9 1.5 9.0 0.9 2.5 1 1 1 2 2 2 0 zinc RING finger of MSL2 DnaJ_C PF01556.18 GBG82858.1 - 1.4e-41 142.0 0.7 1.6e-41 141.8 0.2 1.4 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 GBG82858.1 - 4.2e-23 81.2 1.5 1e-22 80.0 1.5 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GBG82858.1 - 7.1e-15 55.1 20.0 1.5e-14 54.1 20.0 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 GBG82858.1 - 0.17 11.9 8.8 3.1 7.8 1.9 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 GBG82858.1 - 0.27 11.2 14.8 0.057 13.4 1.5 2.8 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 GBG82858.1 - 0.49 10.4 9.3 1.4 9.0 9.3 1.8 1 1 0 1 1 1 0 zinc-ribbons zf-RING_10 PF16685.5 GBG82858.1 - 5.6 7.2 9.9 1.4 9.1 0.9 2.5 1 1 1 2 2 2 0 zinc RING finger of MSL2 DDE_Tnp_4 PF13359.6 GBG82859.1 - 8.5e-29 100.3 0.0 4.9e-27 94.5 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82859.1 - 2.6e-16 59.8 0.0 5.8e-16 58.7 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein CRAL_TRIO PF00650.20 GBG82861.1 - 2.1e-27 95.8 0.1 6.6e-26 90.9 0.1 2.3 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GBG82861.1 - 1.2e-05 25.3 0.2 2.3e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GBG82861.1 - 0.00031 20.9 0.1 0.00046 20.4 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DDE_Tnp_4 PF13359.6 GBG82862.1 - 1.5e-11 44.2 1.0 9.3e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82862.1 - 8.1e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82862.1 - 0.0066 16.1 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG82863.1 - 2.9e-31 108.3 0.0 4.7e-30 104.4 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82863.1 - 3.6e-18 65.9 0.0 7.1e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG82863.1 - 0.0081 16.5 1.3 0.83 10.1 0.0 2.5 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG82863.1 - 0.1 12.2 0.0 9.2 5.8 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain NDK PF00334.19 GBG82864.1 - 8.1e-54 181.3 0.0 8.7e-29 100.3 0.0 2.4 2 1 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 GBG82864.1 - 7.8e-06 25.7 0.1 2.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 DUF1126 PH-like domain rve PF00665.26 GBG82865.1 - 9.7e-06 25.8 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain SspB PF04386.13 GBG82865.1 - 0.086 12.7 1.6 0.17 11.7 1.6 1.4 1 0 0 1 1 1 0 Stringent starvation protein B DUF4637 PF15470.6 GBG82865.1 - 8.6 6.1 10.5 13 5.4 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TBCA PF02970.16 GBG82866.1 - 0.0062 16.8 4.3 0.01 16.2 0.7 2.9 3 0 0 3 3 3 1 Tubulin binding cofactor A TMF_DNA_bd PF12329.8 GBG82866.1 - 0.25 11.4 9.0 0.035 14.1 2.7 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FUSC PF04632.12 GBG82866.1 - 1.2 7.6 3.5 0.59 8.6 1.3 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family RT_RNaseH_2 PF17919.1 GBG82867.1 - 8.9e-28 96.3 0.0 1.9e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82867.1 - 1.4e-25 89.6 0.0 3.1e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82867.1 - 9.3e-16 58.0 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG82867.1 - 8.5e-06 25.6 3.2 1.9e-05 24.5 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG82867.1 - 0.017 14.9 4.1 0.037 13.9 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Nop14 PF04147.12 GBG82867.1 - 2.2 6.4 19.2 3.6 5.7 19.2 1.2 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 GBG82867.1 - 2.9 8.1 12.2 5.1 7.3 12.2 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SRF-TF PF00319.18 GBG82869.1 - 1.4e-26 91.7 0.0 3.2e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.17 GBG82869.1 - 4e-16 59.0 8.4 4e-16 59.0 8.4 2.7 3 0 0 3 3 3 1 K-box region TFIIA PF03153.13 GBG82869.1 - 7.2e-07 29.5 34.4 1e-06 29.0 34.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Vut_1 PF02592.15 GBG82869.1 - 0.3 11.4 3.7 0.19 12.0 0.9 2.0 2 0 0 2 2 2 0 Putative vitamin uptake transporter MgtE PF01769.16 GBG82869.1 - 0.76 10.2 4.9 0.2 12.1 1.4 1.8 2 0 0 2 2 2 0 Divalent cation transporter RVT_1 PF00078.27 GBG82870.1 - 1.1e-08 34.9 0.1 9.8e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG82871.1 - 0.022 13.0 6.1 0.024 12.9 6.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG82871.1 - 0.46 8.7 8.6 0.54 8.5 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Ammonium_transp PF00909.21 GBG82872.1 - 4e-106 355.1 11.9 5.1e-106 354.7 11.9 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family GET2 PF08690.10 GBG82873.1 - 2.1 7.9 6.5 2.6 7.7 6.5 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Chlam_PMP PF02415.17 GBG82874.1 - 8.2e-05 22.8 20.5 0.27 11.8 1.1 5.6 6 0 0 6 6 6 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RFC1 PF08519.12 GBG82876.1 - 5.2e-39 133.9 0.0 9.3e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 GBG82876.1 - 3.8e-17 62.4 0.0 1.2e-16 60.8 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 GBG82876.1 - 1.9e-10 41.3 0.0 4.7e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.7 GBG82876.1 - 2.6e-05 24.1 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain AAA_22 PF13401.6 GBG82876.1 - 0.0023 18.2 0.0 0.007 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG82876.1 - 0.003 17.9 0.1 0.0073 16.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 GBG82876.1 - 0.0048 16.7 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain BRCT_2 PF16589.5 GBG82876.1 - 0.0097 16.3 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rad17 PF03215.15 GBG82876.1 - 0.029 14.3 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_assoc_2 PF16193.5 GBG82876.1 - 0.036 14.4 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_30 PF13604.6 GBG82876.1 - 0.039 13.7 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 GBG82876.1 - 0.05 13.4 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_5 PF07728.14 GBG82876.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 GBG82876.1 - 0.17 11.8 0.0 2.9 7.8 0.0 2.3 1 1 0 1 1 1 0 NACHT domain Herpes_UL52 PF03121.15 GBG82877.1 - 2.1e-12 46.8 0.0 7.4e-12 45.1 0.0 2.0 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Tmemb_9 PF05434.11 GBG82877.1 - 0.00042 20.2 2.2 0.0013 18.7 2.2 1.8 1 0 0 1 1 1 1 TMEM9 YL1 PF05764.13 GBG82877.1 - 0.0015 18.7 10.3 0.0015 18.7 10.3 3.7 3 1 1 4 4 2 1 YL1 nuclear protein DUF4834 PF16118.5 GBG82877.1 - 0.0017 19.3 0.1 0.0017 19.3 0.1 3.9 3 1 0 4 4 2 1 Domain of unknown function (DUF4834) FAM176 PF14851.6 GBG82877.1 - 0.0026 17.4 2.8 0.0026 17.4 2.8 5.2 3 2 2 5 5 1 1 FAM176 family TMEM154 PF15102.6 GBG82877.1 - 0.0057 16.6 0.6 0.0057 16.6 0.6 2.2 2 0 0 2 2 1 1 TMEM154 protein family FHIPEP PF00771.20 GBG82877.1 - 0.011 14.2 0.5 0.017 13.6 0.5 1.2 1 0 0 1 1 1 0 FHIPEP family Ion_trans PF00520.31 GBG82877.1 - 0.013 14.8 0.1 0.028 13.7 0.1 1.4 1 0 0 1 1 1 0 Ion transport protein Pex24p PF06398.11 GBG82877.1 - 0.014 14.4 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin OAD_gamma PF04277.13 GBG82877.1 - 0.015 15.8 0.2 0.063 13.9 0.2 2.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SID-1_RNA_chan PF13965.6 GBG82877.1 - 0.017 13.5 1.7 0.029 12.8 1.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EphA2_TM PF14575.6 GBG82877.1 - 0.021 15.7 1.5 0.021 15.7 1.5 2.7 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mem_trans PF03547.18 GBG82877.1 - 0.024 13.0 0.1 0.037 12.4 0.1 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF1189 PF06691.11 GBG82877.1 - 0.03 13.9 0.1 0.047 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) DUF4191 PF13829.6 GBG82877.1 - 0.037 13.4 4.5 0.068 12.5 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Baculo_11_kDa PF06143.11 GBG82877.1 - 0.044 13.4 4.0 0.13 11.9 4.0 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family 7tm_1 PF00001.21 GBG82877.1 - 0.046 13.1 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) CBP_BcsG PF11658.8 GBG82877.1 - 0.046 12.1 0.6 0.074 11.4 0.6 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG CLN3 PF02487.17 GBG82877.1 - 0.089 11.8 0.5 0.16 11.0 0.5 1.3 1 0 0 1 1 1 0 CLN3 protein SIT PF15330.6 GBG82877.1 - 0.12 12.8 0.3 0.43 11.0 0.3 2.0 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Wzy_C_2 PF11846.8 GBG82877.1 - 0.15 12.0 0.2 0.28 11.1 0.2 1.3 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal LapA_dom PF06305.11 GBG82877.1 - 0.36 10.7 1.1 0.75 9.7 1.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Connexin PF00029.19 GBG82877.1 - 0.37 10.5 6.0 0.24 11.1 3.0 2.2 1 1 1 2 2 2 0 Connexin HemY_N PF07219.13 GBG82877.1 - 0.45 10.7 3.0 1.1 9.5 3.0 1.6 1 0 0 1 1 1 0 HemY protein N-terminus Neur_chan_memb PF02932.16 GBG82877.1 - 5.5 7.0 9.9 0.21 11.6 1.6 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 GBG82877.1 - 6.5 4.5 12.9 0.055 11.4 3.9 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family PP-binding PF00550.25 GBG82878.1 - 1.5e-07 31.7 0.4 3.1e-07 30.6 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site VBS PF08913.10 GBG82878.1 - 0.037 14.5 1.6 4.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Vinculin Binding Site PP-binding PF00550.25 GBG82879.1 - 1.7e-07 31.5 0.4 3.1e-07 30.6 0.4 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site GMP_synt_C PF00958.22 GBG82879.1 - 0.11 12.6 0.3 0.24 11.5 0.3 1.5 1 0 0 1 1 1 0 GMP synthase C terminal domain zf-CCHC_6 PF15288.6 GBG82880.1 - 0.27 11.1 1.0 0.71 9.8 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Chlam_PMP PF02415.17 GBG82881.1 - 0.024 15.1 24.3 0.15 12.6 1.8 5.3 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pkinase_Tyr PF07714.17 GBG82884.1 - 9e-34 116.9 0.0 8.1e-33 113.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82884.1 - 6.7e-33 114.2 0.0 1.6e-21 76.9 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain CD34_antigen PF06365.12 GBG82884.1 - 0.0074 15.9 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Pkinase_fungal PF17667.1 GBG82884.1 - 0.012 14.5 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Lactonase PF10282.9 GBG82884.1 - 0.13 11.5 0.0 0.62 9.3 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Adeno_E3_CR2 PF02439.15 GBG82884.1 - 0.15 11.9 0.7 0.4 10.5 0.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CHRD PF07452.12 GBG82886.1 - 1.6e-09 38.8 5.4 4.3e-08 34.1 0.1 3.3 2 1 1 3 3 3 2 CHRD domain DUF1664 PF07889.12 GBG82887.1 - 0.015 15.3 2.6 0.04 14.0 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fungal_lectin PF07938.12 GBG82887.1 - 0.08 12.3 0.7 0.12 11.8 0.7 1.2 1 0 0 1 1 1 0 Fungal fucose-specific lectin CHRD PF07452.12 GBG82888.1 - 3e-10 41.1 0.1 3e-10 41.1 0.1 3.1 3 1 0 3 3 3 1 CHRD domain CDC27 PF09507.10 GBG82889.1 - 2.7e-19 69.9 22.6 3.2e-19 69.7 0.0 4.6 3 3 0 3 3 3 2 DNA polymerase subunit Cdc27 RT_RNaseH PF17917.1 GBG82890.1 - 2.3e-30 105.0 0.1 6.7e-30 103.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82890.1 - 5.2e-30 103.4 0.0 1.4e-29 102.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82890.1 - 4.4e-08 33.1 0.0 1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG82890.1 - 0.00059 19.4 0.1 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG82890.1 - 0.016 15.4 0.2 0.074 13.3 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG82890.1 - 0.078 12.6 0.6 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Casc1_N PF15927.5 GBG82890.1 - 1.2 8.7 10.1 0.46 10.1 6.9 1.9 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus RVT_1 PF00078.27 GBG82891.1 - 0.00035 20.2 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF745 PF05335.13 GBG82891.1 - 5.4 6.7 8.4 0.18 11.5 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Pkinase_Tyr PF07714.17 GBG82892.1 - 4.6e-80 268.6 0.0 1.8e-39 135.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG82892.1 - 1.3e-67 228.0 0.0 1.5e-34 119.6 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG82892.1 - 3.2e-07 30.5 0.0 0.023 14.6 0.0 2.8 2 0 0 2 2 2 2 Phosphotransferase enzyme family PQQ_3 PF13570.6 GBG82892.1 - 1.5e-06 28.5 1.3 0.18 12.3 0.0 5.2 5 0 0 5 5 5 2 PQQ-like domain CDC45 PF02724.14 GBG82892.1 - 0.00024 19.5 13.0 0.00024 19.5 13.0 2.1 2 0 0 2 2 2 1 CDC45-like protein YL1 PF05764.13 GBG82892.1 - 0.0046 17.1 25.8 0.021 15.0 14.9 2.4 2 0 0 2 2 2 2 YL1 nuclear protein LTV PF04180.14 GBG82892.1 - 0.029 14.1 14.7 0.39 10.4 9.5 2.2 2 0 0 2 2 2 0 Low temperature viability protein SDA1 PF05285.12 GBG82892.1 - 0.039 13.4 34.5 0.61 9.4 1.6 2.2 2 0 0 2 2 2 0 SDA1 DUF2052 PF09747.9 GBG82892.1 - 0.086 13.0 31.3 0.5 10.5 20.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) BUD22 PF09073.10 GBG82892.1 - 0.62 9.3 25.4 0.27 10.6 15.8 2.3 2 0 0 2 2 2 0 BUD22 Plasmodium_Vir PF05795.11 GBG82892.1 - 1.4 8.2 14.0 0.053 13.0 7.8 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein MPP6 PF10175.9 GBG82892.1 - 2.2 8.8 19.9 6.5 7.3 14.1 2.7 2 0 0 2 2 2 0 M-phase phosphoprotein 6 MDM10 PF12519.8 GBG82892.1 - 2.9 6.7 5.1 5.8 5.7 5.1 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 UPF0560 PF10577.9 GBG82892.1 - 3.4 6.1 8.3 5.4 5.4 8.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 NPR3 PF03666.13 GBG82892.1 - 5.1 5.8 7.6 11 4.7 7.6 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Coilin_N PF15862.5 GBG82892.1 - 5.8 6.7 14.5 16 5.3 14.5 1.7 1 0 0 1 1 1 0 Coilin N-terminus ALMT PF11744.8 GBG82892.1 - 8.4 5.1 5.4 21 3.8 5.4 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter Pkinase_Tyr PF07714.17 GBG82893.1 - 3e-39 134.9 0.0 6e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82893.1 - 1.1e-34 120.0 0.0 1.8e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG82893.1 - 0.0024 17.8 0.0 0.0056 16.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family PQQ_3 PF13570.6 GBG82893.1 - 0.024 15.1 0.3 0.09 13.3 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain Pkinase_fungal PF17667.1 GBG82893.1 - 0.035 12.9 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 GBG82895.1 - 2.4e-38 131.9 0.0 6.5e-38 130.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG82895.1 - 5.2e-34 117.8 0.0 8.6e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG82895.1 - 0.0016 18.4 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PQQ_3 PF13570.6 GBG82895.1 - 0.0028 18.1 0.1 0.05 14.1 0.0 2.9 3 0 0 3 3 3 1 PQQ-like domain RT_RNaseH_2 PF17919.1 GBG82897.1 - 3.2e-23 81.7 0.0 1.1e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82897.1 - 4e-20 72.3 0.0 7.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82897.1 - 3.6e-17 62.5 0.0 9.2e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG82897.1 - 0.0046 16.1 4.5 0.033 13.3 0.0 2.4 2 0 0 2 2 2 1 Autophagy protein Apg17 rve PF00665.26 GBG82897.1 - 0.0077 16.4 0.0 0.028 14.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG82899.1 - 8.5e-23 80.3 0.0 1.7e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82899.1 - 2.9e-21 75.7 0.1 7.8e-21 74.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82899.1 - 2.2e-09 37.2 0.1 6e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAPS PF04499.15 GBG82899.1 - 0.14 11.0 13.8 0.0046 15.8 5.1 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Fib_alpha PF08702.10 GBG82899.1 - 6.4 7.0 8.1 1.9 8.7 0.3 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4746 PF15928.5 GBG82899.1 - 9.3 5.6 23.5 0.16 11.3 11.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SLC12 PF03522.15 GBG82901.1 - 4.7 6.1 8.9 6.8 5.6 8.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 GTP_cyclohydroI PF01227.22 GBG82903.1 - 0.014 14.8 0.7 0.025 14.0 0.7 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I RVT_1 PF00078.27 GBG82905.1 - 2.8e-31 108.8 0.0 4.9e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82905.1 - 3.3e-29 100.8 0.0 1e-28 99.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82905.1 - 6.7e-28 97.1 0.0 1.7e-27 95.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG82905.1 - 5.1e-06 26.3 0.0 1.2e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82905.1 - 1.8e-05 25.3 0.0 4.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82905.1 - 0.0017 18.9 0.0 0.0049 17.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG82905.1 - 0.021 14.6 0.0 0.91 9.3 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease DUF1758 PF05585.12 GBG82905.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DRY_EERY PF09750.9 GBG82905.1 - 0.51 10.6 0.0 0.51 10.6 0.0 3.3 3 0 0 3 3 3 0 Alternative splicing regulator Tim54 PF11711.8 GBG82906.1 - 0.0033 16.3 1.3 0.0036 16.1 1.3 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 BUD22 PF09073.10 GBG82906.1 - 0.0093 15.4 8.2 0.0099 15.3 8.2 1.1 1 0 0 1 1 1 1 BUD22 MCM_bind PF09739.9 GBG82906.1 - 0.014 13.9 2.2 0.016 13.7 2.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SDA1 PF05285.12 GBG82906.1 - 0.015 14.7 11.8 0.017 14.5 11.8 1.1 1 0 0 1 1 1 0 SDA1 Eapp_C PF10238.9 GBG82906.1 - 0.02 14.9 0.9 0.023 14.8 0.9 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein CPSF100_C PF13299.6 GBG82906.1 - 0.036 14.2 4.2 0.043 14.0 4.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 GBG82906.1 - 0.046 13.5 3.2 0.057 13.2 3.2 1.1 1 0 0 1 1 1 0 Connexin TRAP_alpha PF03896.16 GBG82906.1 - 0.053 12.7 5.0 0.06 12.6 5.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.11 GBG82906.1 - 0.088 10.9 5.2 0.096 10.8 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SpoIIP PF07454.11 GBG82906.1 - 0.1 12.0 4.5 0.11 12.0 4.5 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 GBG82906.1 - 0.11 12.6 14.2 0.15 12.2 14.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RPN2_C PF18004.1 GBG82906.1 - 0.11 12.4 11.5 0.14 12.1 11.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PI3K_1B_p101 PF10486.9 GBG82906.1 - 0.12 10.1 1.2 0.14 9.9 1.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Mpp10 PF04006.12 GBG82906.1 - 0.13 10.7 14.5 0.15 10.5 14.5 1.0 1 0 0 1 1 1 0 Mpp10 protein FmiP_Thoc5 PF09766.9 GBG82906.1 - 0.13 11.5 5.5 0.16 11.2 5.5 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Pox_Ag35 PF03286.14 GBG82906.1 - 0.17 11.7 8.9 0.2 11.4 8.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CLN3 PF02487.17 GBG82906.1 - 0.2 10.7 0.3 0.23 10.5 0.3 1.1 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 GBG82906.1 - 0.2 11.5 10.9 0.22 11.3 10.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Prothymosin PF03247.14 GBG82906.1 - 0.21 12.1 28.5 0.29 11.6 28.5 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF913 PF06025.12 GBG82906.1 - 0.31 10.0 3.2 0.36 9.8 3.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 GBG82906.1 - 0.49 8.4 17.3 0.56 8.2 17.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 GBG82906.1 - 0.51 9.5 8.3 0.54 9.3 8.3 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RAB3GAP2_C PF14656.6 GBG82906.1 - 0.54 8.4 2.2 0.58 8.3 2.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Nop14 PF04147.12 GBG82906.1 - 0.6 8.3 16.3 0.7 8.0 16.3 1.0 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 GBG82906.1 - 0.78 10.0 8.7 0.92 9.8 8.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 GBG82906.1 - 0.86 7.8 12.6 0.99 7.6 12.6 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 GBG82906.1 - 0.94 9.9 5.5 1.2 9.6 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CobT PF06213.12 GBG82906.1 - 1.2 8.5 18.0 1.5 8.2 18.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Zip PF02535.22 GBG82906.1 - 1.4 8.0 3.0 1.6 7.9 3.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 GBG82906.1 - 1.4 8.2 15.3 1.8 8.0 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Merozoite_SPAM PF07133.11 GBG82906.1 - 1.5 8.8 28.7 1.9 8.5 28.7 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2457 PF10446.9 GBG82906.1 - 1.6 7.8 15.1 1.8 7.6 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFB6 PF17110.5 GBG82906.1 - 1.7 8.4 7.6 2.1 8.1 7.6 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4637 PF15470.6 GBG82906.1 - 1.8 8.2 15.1 2.5 7.8 15.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF5523 PF17661.1 GBG82906.1 - 2.2 7.9 16.7 2.8 7.6 16.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) NOA36 PF06524.12 GBG82906.1 - 2.3 7.5 13.5 2.9 7.1 13.5 1.1 1 0 0 1 1 1 0 NOA36 protein NARP1 PF12569.8 GBG82906.1 - 2.5 6.9 7.6 2.8 6.7 7.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 GBG82906.1 - 2.9 6.6 7.9 3.4 6.3 7.9 1.1 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 GBG82906.1 - 4 5.9 22.0 4.9 5.6 22.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SspB PF04386.13 GBG82906.1 - 4.3 7.2 8.5 5.5 6.9 8.5 1.2 1 0 0 1 1 1 0 Stringent starvation protein B DUF2828 PF11443.8 GBG82906.1 - 4.3 5.3 5.7 5.2 5.0 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RNA_pol_3_Rpc31 PF11705.8 GBG82906.1 - 5.4 7.2 21.1 7 6.8 21.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NPR3 PF03666.13 GBG82906.1 - 5.9 5.6 8.2 7 5.3 8.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4820 PF16091.5 GBG82906.1 - 6.1 6.1 8.0 8.1 5.7 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Paf1 PF03985.13 GBG82906.1 - 6.5 5.6 20.9 7.9 5.4 20.9 1.0 1 0 0 1 1 1 0 Paf1 Nop53 PF07767.11 GBG82906.1 - 6.9 6.0 19.4 8.1 5.7 19.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Hid1 PF12722.7 GBG82906.1 - 7.6 4.5 4.7 8.4 4.4 4.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleo_P87 PF07267.11 GBG82906.1 - 7.9 5.2 9.5 9.7 4.9 9.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PQQ_3 PF13570.6 GBG82907.1 - 3.6 8.2 7.0 19 5.9 2.8 2.8 2 1 0 2 2 2 0 PQQ-like domain C2 PF00168.30 GBG82908.1 - 1.4e-07 31.7 0.0 1.4e-06 28.5 0.0 2.4 2 0 0 2 2 2 1 C2 domain Exo_endo_phos PF03372.23 GBG82908.1 - 6.5e-06 25.8 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PUA PF01472.20 GBG82909.1 - 3.8e-17 62.0 0.1 5.1e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 PUA domain RepB-RCR_reg PF10723.9 GBG82910.1 - 0.064 13.2 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Replication regulatory protein RepB CdvA PF18822.1 GBG82910.1 - 2 8.3 7.5 0.19 11.5 2.2 1.9 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Dec-1 PF04624.14 GBG82911.1 - 1.2 9.1 4.6 2.6 8.0 4.6 1.5 1 0 0 1 1 1 0 Dec-1 repeat Cwf_Cwc_15 PF04889.12 GBG82912.1 - 0.0088 15.8 5.0 0.0097 15.7 5.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 GBG82912.1 - 0.011 15.8 4.7 0.015 15.5 4.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Myb_DNA-bind_4 PF13837.6 GBG82912.1 - 0.015 15.6 0.3 0.035 14.5 0.3 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myc_N PF01056.18 GBG82912.1 - 0.02 14.8 1.7 0.023 14.6 1.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region LAT PF15234.6 GBG82912.1 - 0.054 13.2 5.8 0.09 12.5 5.7 1.3 1 1 0 1 1 1 0 Linker for activation of T-cells MMU163 PF17119.5 GBG82912.1 - 0.52 9.4 2.0 0.74 8.9 2.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis CDC45 PF02724.14 GBG82912.1 - 3.1 6.0 9.6 3.7 5.7 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4416 PF14385.6 GBG82913.1 - 0.013 15.4 0.4 0.022 14.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) RVT_1 PF00078.27 GBG82914.1 - 1.1e-32 113.3 0.1 2e-32 112.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82914.1 - 1.7e-31 108.2 0.0 1.1e-29 102.3 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82914.1 - 4.7e-30 104.0 0.1 2.1e-29 101.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG82914.1 - 0.23 11.1 0.0 0.23 11.1 0.0 3.2 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase TssO PF17561.2 GBG82914.1 - 1.1 9.4 5.9 11 6.1 6.1 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF2950 PF11453.8 GBG82914.1 - 4.5 6.4 9.7 7.6 5.6 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Herpes_UL25 PF01499.16 GBG82914.1 - 4.9 5.5 6.8 8.3 4.8 6.8 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF659 PF04937.15 GBG82915.1 - 0.0016 18.3 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG82915.1 - 0.0017 18.1 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Exostosin PF03016.15 GBG82916.1 - 2.5e-48 164.8 0.4 2.1e-24 86.3 0.0 2.1 2 0 0 2 2 2 2 Exostosin family Serglycin PF04360.12 GBG82917.1 - 0.034 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Serglycin Lsr2 PF11774.8 GBG82917.1 - 0.068 13.3 2.4 0.074 13.2 0.1 2.2 2 1 1 3 3 3 0 Lsr2 ER_lumen_recept PF00810.18 GBG82918.1 - 5.9e-56 189.4 9.9 9.8e-56 188.7 9.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 GBG82918.1 - 0.0023 17.7 3.5 0.26 11.1 0.3 3.1 2 1 0 2 2 2 2 PQ loop repeat DUF1129 PF06570.11 GBG82918.1 - 2.3 7.7 7.8 0.28 10.7 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) EMP70 PF02990.16 GBG82919.1 - 1.6e-220 733.2 13.8 2.3e-220 732.7 13.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 CopD PF05425.13 GBG82919.1 - 1.4 9.3 15.8 0.26 11.7 4.7 3.5 3 1 1 4 4 4 0 Copper resistance protein D RT_RNaseH_2 PF17919.1 GBG82920.1 - 1.6e-27 95.5 0.0 1.3e-13 50.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82920.1 - 2.8e-27 95.0 0.0 6.4e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82920.1 - 6.1e-25 88.0 0.1 1.4e-24 86.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82920.1 - 4.3e-13 49.2 1.9 4.5e-13 49.1 0.4 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG82920.1 - 0.002 18.3 0.3 0.0068 16.6 0.3 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Dimer_Tnp_hAT PF05699.14 GBG82921.1 - 1.2e-05 24.9 0.1 3.8e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region EF_assoc_2 PF08356.12 GBG82922.1 - 7.2e-31 106.0 0.0 2.6e-30 104.3 0.0 1.9 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 GBG82922.1 - 1.3e-26 93.1 0.0 2.9e-18 66.0 0.0 2.6 2 1 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 GBG82922.1 - 9.2e-17 60.4 0.0 2.1e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 GBG82922.1 - 6.8e-14 52.1 0.0 1.2e-06 28.7 0.0 3.0 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GBG82922.1 - 1.2e-06 28.6 0.4 0.0014 18.7 0.0 2.8 2 2 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_6 PF13405.6 GBG82922.1 - 2.8e-06 26.8 2.5 0.0095 15.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GBG82922.1 - 1.3e-05 25.5 0.3 0.092 13.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.23 GBG82922.1 - 7.3e-05 22.9 0.1 0.1 12.7 0.0 2.7 3 0 0 3 3 3 2 Dynamin family EF-hand_1 PF00036.32 GBG82922.1 - 7.9e-05 21.9 5.7 0.014 14.9 0.5 2.6 2 0 0 2 2 2 2 EF hand Arf PF00025.21 GBG82922.1 - 0.00083 18.9 0.0 3.9 6.9 0.0 3.5 4 0 0 4 4 4 1 ADP-ribosylation factor family AAA_29 PF13555.6 GBG82922.1 - 0.0014 18.3 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GBG82922.1 - 0.0018 18.5 0.5 3.5 7.9 0.1 3.5 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG82922.1 - 0.0037 17.7 0.0 0.39 11.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 GBG82922.1 - 0.014 15.7 0.1 7.2 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GBG82922.1 - 0.015 15.2 0.0 16 5.4 0.0 3.5 4 0 0 4 4 4 0 RsgA GTPase ABC_tran PF00005.27 GBG82922.1 - 0.062 13.8 0.0 5.4 7.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter EF-hand_10 PF14788.6 GBG82922.1 - 0.064 13.1 1.2 0.092 12.6 0.1 1.9 2 0 0 2 2 1 0 EF hand ATPase_2 PF01637.18 GBG82922.1 - 0.075 12.9 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 GBG82922.1 - 0.11 12.8 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 GBG82922.1 - 0.14 11.9 0.2 3.4 7.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 GBG82922.1 - 0.19 10.8 0.0 0.46 9.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IIGP PF05049.13 GBG82922.1 - 0.22 10.6 0.0 0.42 9.6 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Retrotrans_gag PF03732.17 GBG82923.1 - 0.00052 20.2 0.4 0.00052 20.2 0.4 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG82923.1 - 0.0035 17.1 0.3 0.0093 15.7 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) TFIIA PF03153.13 GBG82923.1 - 0.96 9.4 13.9 0.16 12.0 8.0 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3947 PF13135.6 GBG82923.1 - 3.5 7.9 7.6 11 6.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3947) zf-CCHC PF00098.23 GBG82925.1 - 2.1e-08 33.9 3.8 3.3e-08 33.2 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG82925.1 - 0.0079 16.0 0.7 0.014 15.2 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG82925.1 - 0.029 14.2 1.6 0.066 13.1 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4193 PF13834.6 GBG82925.1 - 0.065 13.7 2.6 0.09 13.3 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) zf-CCHC_3 PF13917.6 GBG82925.1 - 0.07 13.1 0.4 0.14 12.2 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG82925.1 - 0.41 10.4 1.3 0.76 9.6 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Atg14 PF10186.9 GBG82925.1 - 0.57 9.2 5.3 0.85 8.6 5.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spore_YhcN_YlaJ PF09580.10 GBG82925.1 - 6.8 6.7 7.0 3.1 7.9 1.2 2.7 2 1 1 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Rhomboid PF01694.22 GBG82926.1 - 7.7e-28 97.4 11.4 7.7e-28 97.4 11.4 2.3 3 0 0 3 3 3 1 Rhomboid family RUN PF02759.19 GBG82926.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RUN domain SafA PF17073.5 GBG82926.1 - 0.071 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Two-component-system connector protein GWT1 PF06423.12 GBG82926.1 - 0.18 11.9 0.4 3.7 7.7 0.3 2.3 2 1 0 2 2 2 0 GWT1 Peptidase_U4 PF03419.13 GBG82926.1 - 2.8 7.2 7.6 7.5 5.7 7.1 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA TssN PF17555.2 GBG82926.1 - 3.3 7.0 5.7 3 7.1 0.5 2.8 3 0 0 3 3 3 0 Type VI secretion system, TssN zf-CCHC PF00098.23 GBG82928.1 - 0.0045 17.0 0.5 0.0077 16.3 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Fer4_16 PF13484.6 GBG82928.1 - 0.98 10.4 3.9 11 7.0 0.0 2.8 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain RNA_GG_bind PF10258.9 GBG82929.1 - 1.7e-21 76.1 0.0 4e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 PHAX RNA-binding domain DNA_pol_B_thumb PF14791.6 GBG82930.1 - 0.078 13.1 0.3 0.078 13.1 0.3 1.9 2 1 0 2 2 2 0 DNA polymerase beta thumb SelK_SelG PF10961.8 GBG82931.1 - 0.28 11.8 2.1 0.28 11.8 0.1 2.0 2 0 0 2 2 2 0 Selenoprotein SelK_SelG RVT_1 PF00078.27 GBG82932.1 - 7.4e-36 123.7 0.1 1.1e-35 123.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82932.1 - 2.7e-29 101.5 0.0 5.4e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG82932.1 - 2.8e-29 101.1 0.0 7.8e-29 99.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82932.1 - 2.5e-12 46.7 0.1 5.9e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG82932.1 - 1.2e-05 25.0 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG82932.1 - 0.00024 21.7 0.0 0.00072 20.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG82932.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF4392 PF14336.6 GBG82932.1 - 0.035 13.6 0.2 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) gag-asp_proteas PF13975.6 GBG82932.1 - 0.081 13.5 0.0 0.22 12.1 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease SAPS PF04499.15 GBG82932.1 - 0.79 8.4 5.0 1.2 7.9 5.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG82932.1 - 1.3 7.1 26.8 2.2 6.4 26.8 1.2 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_88 PF07470.13 GBG82933.1 - 4.6e-79 266.0 0.0 6.1e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DDE_Tnp_4 PF13359.6 GBG82934.1 - 4.7e-23 81.6 0.0 7.3e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82934.1 - 1.2e-12 47.9 0.0 1.8e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82934.1 - 0.0016 18.1 2.8 0.018 14.7 0.3 2.5 3 0 0 3 3 3 1 Transposase DDE domain SAP PF02037.27 GBG82936.1 - 0.053 13.3 1.3 0.13 12.0 1.3 1.7 1 0 0 1 1 1 0 SAP domain FTCD_C PF04961.12 GBG82936.1 - 5.6 6.7 7.2 3.5 7.3 3.3 2.2 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase RVT_1 PF00078.27 GBG82937.1 - 7.2e-08 32.2 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cwf_Cwc_15 PF04889.12 GBG82937.1 - 0.016 14.9 23.4 0.022 14.5 23.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG82937.1 - 0.084 12.3 29.1 0.1 12.0 29.1 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 GBG82937.1 - 0.086 12.4 19.6 0.12 12.0 19.6 1.3 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 GBG82937.1 - 0.2 9.9 22.2 0.25 9.6 22.2 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG82937.1 - 0.38 10.1 30.8 0.58 9.4 30.8 1.2 1 0 0 1 1 1 0 BUD22 DUF2828 PF11443.8 GBG82937.1 - 0.53 8.3 5.1 0.66 8.0 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Nop14 PF04147.12 GBG82937.1 - 0.79 7.9 31.4 1 7.5 31.4 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG82937.1 - 0.83 8.4 9.6 0.85 8.3 9.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 GBG82937.1 - 1.2 8.6 18.1 1.7 8.1 18.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4614 PF15391.6 GBG82937.1 - 2.6 8.0 11.8 64 3.5 11.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Zip PF02535.22 GBG82937.1 - 4.7 6.3 9.5 6.1 6.0 9.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 GBG82937.1 - 6.3 4.8 15.8 8.1 4.4 15.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Serinc PF03348.15 GBG82937.1 - 7.5 5.4 4.6 9.7 5.0 4.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 GBG82937.1 - 8.1 5.1 17.6 10 4.8 17.6 1.2 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 GBG82937.1 - 8.9 5.3 17.4 11 5.0 17.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SURF2 PF05477.11 GBG82937.1 - 9.6 5.8 17.9 14 5.3 17.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Dimer_Tnp_hAT PF05699.14 GBG82938.1 - 3.9e-05 23.3 0.1 7.5e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Latarcin PF10279.9 GBG82938.1 - 0.051 14.0 0.3 0.38 11.2 0.0 2.1 2 0 0 2 2 2 0 Latarcin precursor LUC7 PF03194.15 GBG82939.1 - 2.2e-72 243.8 15.3 1.7e-41 142.5 7.5 2.2 2 0 0 2 2 2 2 LUC7 N_terminus PAP_central PF04928.17 GBG82939.1 - 0.099 11.6 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain SMBP PF16785.5 GBG82939.1 - 0.15 12.3 2.2 0.27 11.5 0.1 2.2 2 1 1 3 3 3 0 Small metal-binding protein YfdX PF10938.8 GBG82939.1 - 5.4 6.9 8.5 14 5.6 2.4 2.4 2 1 0 2 2 2 0 YfdX protein Q_salvage PF10343.9 GBG82940.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family SRP-alpha_N PF04086.13 GBG82941.1 - 0.023 14.6 10.9 0.015 15.3 8.5 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Retrotrans_gag PF03732.17 GBG82941.1 - 0.024 14.9 0.2 0.11 12.8 0.1 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein Histone PF00125.24 GBG82942.1 - 1.8e-20 73.6 0.0 1.8e-20 73.6 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG82942.1 - 0.086 13.2 0.3 0.24 11.8 0.3 1.7 1 0 0 1 1 1 0 CENP-S protein RT_RNaseH_2 PF17919.1 GBG82944.1 - 4.1e-22 78.1 0.0 9.6e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82944.1 - 1.7e-21 76.5 0.0 3.5e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG82944.1 - 0.00027 21.4 0.5 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG82944.1 - 0.0034 18.0 0.0 0.01 16.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG82944.1 - 0.021 15.1 1.3 0.82 10.0 0.0 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein RVP PF00077.20 GBG82944.1 - 0.15 12.4 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Taeniidae_ag PF05596.11 GBG82945.1 - 0.0039 17.1 2.3 1 9.4 0.1 2.4 2 0 0 2 2 2 2 Taeniidae antigen PGA_cap PF09587.10 GBG82945.1 - 0.13 11.7 1.9 0.21 11.0 1.9 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap VIT1 PF01988.19 GBG82945.1 - 1.8 8.4 4.6 2.8 7.8 4.6 1.3 1 0 0 1 1 1 0 VIT family Ribosomal_L37 PF08561.10 GBG82945.1 - 2.7 8.5 11.0 7.1 7.2 11.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 DUF3464 PF11947.8 GBG82945.1 - 4.5 7.0 7.1 10 5.9 7.1 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 LSM14 PF12701.7 GBG82946.1 - 2.7e-33 113.9 0.2 4.1e-33 113.3 0.2 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 GBG82946.1 - 8.6e-17 61.9 1.9 2.6e-16 60.4 1.9 1.7 1 1 0 1 1 1 1 FDF domain SM-ATX PF14438.6 GBG82946.1 - 1.2e-12 47.8 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 GBG82946.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 GBG82947.1 - 2.6e-33 113.9 0.2 4e-33 113.3 0.2 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 GBG82947.1 - 8.1e-17 62.0 1.9 2.5e-16 60.5 1.9 1.8 1 1 0 1 1 1 1 FDF domain SM-ATX PF14438.6 GBG82947.1 - 1.1e-12 47.9 0.0 1.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 GBG82947.1 - 0.0097 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF179 PF02622.15 GBG82948.1 - 4.8e-12 46.1 0.0 3.1e-10 40.2 0.0 2.4 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 RVT_1 PF00078.27 GBG82949.1 - 7e-32 110.7 0.5 1.2e-31 110.0 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG82949.1 - 4.3e-15 55.6 0.0 1.3e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82949.1 - 2.1e-11 44.0 0.0 6.1e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG82949.1 - 0.051 12.7 0.1 0.2 10.7 0.1 1.7 1 1 0 1 1 1 0 Autophagy protein Apg17 Se-cys_synth_N PF12390.8 GBG82949.1 - 0.38 11.0 2.9 13 6.1 0.5 2.9 3 0 0 3 3 3 0 Selenocysteine synthase N terminal DUF659 PF04937.15 GBG82951.1 - 3.8e-35 121.0 0.8 8.4e-35 119.9 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG82951.1 - 8.3e-31 106.0 0.0 2e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82951.1 - 3.2e-30 104.5 0.0 7.9e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82951.1 - 2e-19 69.5 0.2 5.4e-19 68.0 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG82951.1 - 3.7e-11 43.0 0.0 7.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG82951.1 - 4.5e-07 29.7 0.0 8.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG82951.1 - 0.00011 22.4 0.0 0.0012 19.0 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG82951.1 - 0.00029 21.4 0.0 0.00067 20.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82951.1 - 0.00062 20.3 0.0 0.0016 18.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Dehydrin PF00257.19 GBG82951.1 - 0.004 17.7 2.4 0.008 16.8 2.4 1.4 1 0 0 1 1 1 1 Dehydrin DUF1758 PF05585.12 GBG82951.1 - 0.0062 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG82951.1 - 0.0095 16.1 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Porin_5 PF16930.5 GBG82951.1 - 1.1 7.7 3.2 1.7 7.0 3.2 1.2 1 0 0 1 1 1 0 Putative porin RINGv PF12906.7 GBG82952.1 - 2.6e-09 37.1 1.1 2.6e-09 37.1 1.1 3.1 3 0 0 3 3 3 1 RING-variant domain DUF5402 PF17393.2 GBG82952.1 - 0.00026 20.9 1.0 2.7 7.9 0.1 3.2 2 1 0 3 3 3 3 Family of unknown function (DUF5402) NPR3 PF03666.13 GBG82953.1 - 0.16 10.7 14.0 0.18 10.6 14.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 GBG82953.1 - 0.55 9.6 53.2 0.68 9.3 53.2 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG82953.1 - 0.78 8.4 22.3 0.94 8.2 22.3 1.1 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 GBG82953.1 - 6.5 6.9 22.7 8.8 6.4 22.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SAPS PF04499.15 GBG82953.1 - 9.8 4.8 19.6 11 4.7 19.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPR_2 PF13041.6 GBG82954.1 - 0.00022 21.3 0.0 0.0093 16.1 0.0 2.8 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.6 GBG82954.1 - 0.036 14.1 0.0 0.36 11.0 0.0 2.2 1 1 0 2 2 2 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG82954.1 - 0.037 13.7 3.8 0.13 12.0 1.2 2.8 2 1 0 2 2 2 0 PPR repeat RT_RNaseH_2 PF17919.1 GBG82955.1 - 2.1e-14 53.3 0.0 3.6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82955.1 - 6.8e-07 29.0 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG82955.1 - 0.00058 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BSP_II PF05432.11 GBG82955.1 - 0.047 13.4 27.8 0.07 12.8 27.8 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Cwf_Cwc_15 PF04889.12 GBG82955.1 - 1.4 8.6 22.3 2.3 7.9 22.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG82955.1 - 4.9 5.2 29.0 6.6 4.8 29.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG82955.1 - 5.4 5.2 22.8 7.4 4.7 22.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GBG82955.1 - 8.5 5.0 8.3 11 4.6 8.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RT_RNaseH_2 PF17919.1 GBG82956.1 - 6.8e-28 96.6 0.0 1e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82956.1 - 8e-24 83.9 0.0 1.2e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82956.1 - 1.4e-11 44.3 0.0 2.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Amidase PF01425.21 GBG82957.1 - 1.2e-53 182.7 0.0 4.6e-50 170.9 0.2 2.7 2 1 0 2 2 2 2 Amidase NPR3 PF03666.13 GBG82958.1 - 0.031 13.1 2.3 0.044 12.6 2.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 GBG82958.1 - 0.15 10.3 6.5 0.18 10.0 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GBG82958.1 - 0.24 9.9 1.7 0.3 9.6 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Paf1 PF03985.13 GBG82958.1 - 3.3 6.6 13.1 4.5 6.2 13.1 1.1 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 GBG82958.1 - 7.7 5.8 12.4 11 5.3 12.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Myb_DNA-bind_4 PF13837.6 GBG82959.1 - 6.9e-13 48.8 3.8 2.2e-05 24.7 0.1 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG82959.1 - 0.00037 20.5 2.8 0.36 10.9 0.1 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain TraI_2_C PF07515.11 GBG82959.1 - 0.034 14.1 0.1 10 6.1 0.0 2.2 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term APP_E2 PF12925.7 GBG82959.1 - 0.1 12.3 1.0 5.6 6.6 0.2 2.2 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein MobA_MobL PF03389.15 GBG82959.1 - 0.11 12.2 2.1 0.66 9.7 0.3 2.3 2 0 0 2 2 2 0 MobA/MobL family MADF_DNA_bdg PF10545.9 GBG82959.1 - 0.4 11.0 2.0 14 6.0 0.1 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HTH_10 PF04967.12 GBG82959.1 - 0.84 9.5 2.7 1.1e+02 2.7 0.0 3.3 3 0 0 3 3 3 0 HTH DNA binding domain zf-RING_2 PF13639.6 GBG82960.1 - 1.2e-11 44.8 6.2 1.2e-11 44.8 6.2 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG82960.1 - 9.4e-11 41.4 6.3 9.4e-11 41.4 6.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG82960.1 - 6e-07 29.1 1.4 6e-07 29.1 1.4 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GBG82960.1 - 1.3e-05 24.9 4.7 1.3e-05 24.9 4.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG82960.1 - 1.7e-05 25.0 8.0 1.7e-05 25.0 8.0 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GBG82960.1 - 0.0001 22.3 2.2 0.00085 19.3 0.8 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GBG82960.1 - 0.00011 22.0 3.6 0.00011 22.0 3.6 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GBG82960.1 - 0.00033 20.6 3.6 0.00033 20.6 3.6 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GBG82960.1 - 0.00038 20.2 3.3 0.00038 20.2 3.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 GBG82960.1 - 0.00053 20.2 0.4 0.00053 20.2 0.4 2.7 3 0 0 3 3 3 1 zinc-ribbon zf-RING_5 PF14634.6 GBG82960.1 - 0.0055 16.6 3.3 0.0055 16.6 3.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING-like PF08746.11 GBG82960.1 - 0.014 15.7 3.9 0.014 15.7 3.9 1.8 2 0 0 2 2 2 0 RING-like domain Zn_ribbon_17 PF17120.5 GBG82960.1 - 0.17 11.5 4.7 0.38 10.4 4.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 GBG82960.1 - 0.89 9.4 3.3 4.2 7.3 0.6 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Nse PF11789.8 GBG82960.1 - 2.2 8.2 5.2 1.7 8.5 2.7 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 GBG82960.1 - 5.4 7.2 5.2 10 6.3 5.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 GBG82960.1 - 9.6 6.3 7.7 0.67 10.0 2.2 1.8 2 0 0 2 2 2 0 Zinc-finger HA2 PF04408.23 GBG82962.1 - 3.1e-21 75.7 0.0 7.3e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GBG82962.1 - 9.4e-19 67.8 0.0 2.2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GBG82962.1 - 1.2e-18 67.3 0.0 2.5e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GBG82962.1 - 0.00064 19.5 0.2 0.13 12.0 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase T2SSE PF00437.20 GBG82962.1 - 0.0071 15.4 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 GBG82962.1 - 0.043 14.1 1.1 0.25 11.6 0.1 2.4 1 1 1 2 2 2 0 AAA domain Terminase_4 PF05119.12 GBG82962.1 - 0.062 13.7 0.4 22 5.5 0.0 2.8 2 0 0 2 2 2 0 Phage terminase, small subunit Rad17 PF03215.15 GBG82962.1 - 0.08 12.9 0.1 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain LysM PF01476.20 GBG82963.1 - 8.1e-10 38.6 0.0 1.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 LysM domain Retrotrans_gag PF03732.17 GBG82964.1 - 0.0034 17.6 1.0 0.026 14.8 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein Phage_lysozyme PF00959.19 GBG82964.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Phage lysozyme gpUL132 PF11359.8 GBG82964.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 FAM184 PF15665.5 GBG82965.1 - 0.011 15.5 9.5 0.018 14.8 9.5 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF4287 PF14117.6 GBG82965.1 - 0.54 10.4 2.1 2.4 8.4 0.3 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4287) Hrs_helical PF12210.8 GBG82965.1 - 7.5 7.2 8.9 11 6.6 4.3 2.3 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate RT_RNaseH_2 PF17919.1 GBG82966.1 - 6.9e-30 103.0 0.0 1.8e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82966.1 - 4.5e-29 100.8 0.1 1.2e-28 99.4 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG82966.1 - 5.4e-15 55.3 0.1 1.4e-14 53.9 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG82966.1 - 0.03 14.5 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG82966.1 - 0.042 13.4 0.1 0.078 12.5 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_23 PF13476.6 GBG82966.1 - 0.068 13.7 9.8 0.039 14.4 3.8 2.6 2 0 0 2 2 2 0 AAA domain VIR_N PF15912.5 GBG82966.1 - 1.7 8.2 5.4 4.6 6.8 5.4 1.7 1 0 0 1 1 1 0 Virilizer, N-terminal Borrelia_P83 PF05262.11 GBG82966.1 - 4.9 5.5 17.1 7.3 5.0 17.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Exonuc_VII_L PF02601.15 GBG82966.1 - 8.3 5.9 7.7 9.4 5.7 6.2 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit CSRNP_N PF16019.5 GBG82966.1 - 8.8 6.2 10.6 0.3 11.0 3.3 2.0 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus SDA1 PF05285.12 GBG82967.1 - 0.013 15.0 22.1 0.016 14.6 22.1 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG82967.1 - 0.067 12.0 10.1 0.092 11.5 10.1 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 GBG82967.1 - 0.17 10.7 8.9 0.22 10.3 8.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Asp_protease_2 PF13650.6 GBG82968.1 - 6.5e-08 33.1 0.0 1.4e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG82968.1 - 9.3e-06 26.1 0.0 1.9e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG82968.1 - 5.4e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG82968.1 - 0.00026 20.8 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF3834 PF12916.7 GBG82969.1 - 0.039 13.2 0.2 0.093 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) CM_2 PF01817.21 GBG82969.1 - 0.17 12.3 3.1 2.1 8.8 0.7 2.7 2 1 0 2 2 2 0 Chorismate mutase type II RT_RNaseH_2 PF17919.1 GBG82970.1 - 9e-28 96.3 0.0 2e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82970.1 - 2.1e-26 92.3 0.0 4.3e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82970.1 - 1.2e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3807 PF12720.7 GBG82970.1 - 2.3 8.5 12.5 3.9 7.7 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SDA1 PF05285.12 GBG82970.1 - 5.2 6.4 25.3 6.9 6.0 25.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG82970.1 - 8.4 4.5 21.2 12 4.0 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG82970.1 - 9 5.6 14.0 14 5.0 14.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Peripla_BP_2 PF01497.18 GBG82971.1 - 1.8e-06 27.7 0.4 2.1e-05 24.2 0.2 2.5 2 1 0 2 2 2 1 Periplasmic binding protein Dicer_N PF17895.1 GBG82971.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain DUF3138 PF11336.8 GBG82972.1 - 0.31 9.6 8.0 0.6 8.7 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) ACC_epsilon PF13822.6 GBG82972.1 - 1.6 9.5 4.9 2.1 9.1 2.0 2.9 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit CM_2 PF01817.21 GBG82973.1 - 0.2 12.1 3.0 2.7 8.4 0.5 2.7 2 1 0 2 2 2 0 Chorismate mutase type II DUF3834 PF12916.7 GBG82973.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) DDE_Tnp_4 PF13359.6 GBG82975.1 - 2.4e-30 105.3 0.0 3.5e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82975.1 - 2.2e-12 47.0 0.0 3.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82975.1 - 0.0066 16.1 0.5 0.71 9.5 0.3 2.3 2 0 0 2 2 2 2 Transposase DDE domain START PF01852.19 GBG82976.1 - 0.11 11.9 0.9 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 START domain DDE_Tnp_4 PF13359.6 GBG82977.1 - 4e-28 98.1 0.1 2e-27 95.8 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG82977.1 - 1.7e-14 53.9 0.0 3.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG82977.1 - 1.9e-05 24.4 0.2 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG82977.1 - 0.036 14.4 0.1 0.084 13.3 0.1 1.6 1 0 0 1 1 1 0 Transposase DDE domain RT_RNaseH PF17917.1 GBG82978.1 - 3.1e-22 78.8 0.0 6.9e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG82978.1 - 1.7e-16 60.4 0.1 3e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG82978.1 - 4.1e-15 55.6 0.0 1.3e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG82978.1 - 2.4e-12 46.8 0.0 4.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG82978.1 - 7e-12 45.6 0.0 3e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG82978.1 - 7e-05 23.0 0.0 0.00021 21.5 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Pkinase PF00069.25 GBG82979.1 - 6.7e-16 58.4 0.0 3.8e-15 56.0 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG82979.1 - 5.1e-15 55.5 0.0 2.4e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase WD40 PF00400.32 GBG82979.1 - 2.8e-07 31.1 1.2 1.6e-05 25.5 0.3 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG82979.1 - 0.082 13.2 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain HR1 PF02185.16 GBG82979.1 - 0.64 10.2 7.8 0.15 12.2 2.1 2.5 2 0 0 2 2 2 0 Hr1 repeat TPR_MLP1_2 PF07926.12 GBG82979.1 - 0.64 10.1 8.2 1.7 8.7 3.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SOAR PF16533.5 GBG82979.1 - 1.3 9.0 4.3 4.1 7.4 4.3 1.8 1 0 0 1 1 1 0 STIM1 Orai1-activating region KELK PF15796.5 GBG82979.1 - 7.3 7.1 12.4 0.6 10.6 7.0 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Dimer_Tnp_hAT PF05699.14 GBG82980.1 - 8.5e-07 28.7 0.1 1.8e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Merozoite_SPAM PF07133.11 GBG82981.1 - 0.27 11.2 13.4 3 7.8 0.0 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Presenilin PF01080.17 GBG82981.1 - 9.5 4.9 7.1 11 4.6 7.1 1.2 1 0 0 1 1 1 0 Presenilin DUF659 PF04937.15 GBG82983.1 - 1.4e-14 54.2 0.0 2.7e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG82983.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF898 PF05987.13 GBG82985.1 - 1.1 8.2 7.5 9.2 5.2 4.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Integrase_H2C2 PF17921.1 GBG82986.1 - 1.4e-16 60.4 0.2 4e-16 58.9 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG82986.1 - 1.8e-08 34.6 0.0 5.3e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG82986.1 - 1.1e-05 25.6 1.4 0.00079 19.7 0.1 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG82986.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain SURNod19 PF07712.12 GBG82988.1 - 0.092 11.5 0.2 0.14 10.9 0.2 1.1 1 0 0 1 1 1 0 Stress up-regulated Nod 19 Acyl_transf_2 PF02273.15 GBG82988.1 - 0.14 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Acyl transferase Arm PF00514.23 GBG82988.1 - 0.25 11.5 4.0 2 8.6 0.1 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Eapp_C PF10238.9 GBG82989.1 - 0.11 12.6 0.9 0.11 12.5 0.9 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4366 PF14283.6 GBG82989.1 - 0.19 11.7 1.0 0.29 11.2 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 GBG82989.1 - 0.2 10.4 1.1 0.2 10.4 1.1 1.0 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 GBG82989.1 - 0.29 10.5 1.7 0.26 10.7 1.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RVT_1 PF00078.27 GBG82990.1 - 1.1e-30 106.9 0.1 1.5e-30 106.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG82990.1 - 1.1e-12 47.7 0.0 2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_4 PF13837.6 GBG82991.1 - 8.8e-08 32.4 0.5 3e-07 30.7 0.5 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG82991.1 - 0.0023 18.2 0.3 0.0065 16.8 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG82991.1 - 0.083 13.1 0.2 0.34 11.2 0.2 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain PI-PLC-X PF00388.19 GBG82993.1 - 8.4e-45 151.9 0.0 1.7e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain RVT_1 PF00078.27 GBG82993.1 - 1.7e-27 96.4 0.1 3.8e-27 95.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PI-PLC-Y PF00387.19 GBG82993.1 - 7.1e-26 90.8 0.1 2.4e-25 89.1 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain rve PF00665.26 GBG82993.1 - 3.3e-09 37.0 0.0 8.6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG82993.1 - 3.1e-08 33.6 0.0 8.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase C2 PF00168.30 GBG82993.1 - 0.00021 21.5 0.0 0.00075 19.8 0.0 1.9 2 0 0 2 2 2 1 C2 domain Retrotrans_gag PF03732.17 GBG82993.1 - 0.0013 18.9 0.4 0.12 12.7 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG82994.1 - 5.2e-05 23.1 5.9 5.2e-05 23.1 5.9 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG82994.1 - 0.0053 16.7 3.3 0.018 15.0 3.3 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG82994.1 - 0.025 14.4 9.4 0.098 12.5 5.6 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF1682 PF07946.14 GBG82994.1 - 0.62 9.2 21.8 1 8.5 21.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Menin PF05053.13 GBG82994.1 - 0.65 8.3 9.8 0.89 7.8 9.8 1.1 1 0 0 1 1 1 0 Menin Fmp27 PF10344.9 GBG82994.1 - 1.1 7.2 5.5 1.6 6.8 5.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 SmAKAP PF15127.6 GBG82994.1 - 2.1 9.6 15.6 0.31 12.3 10.2 2.5 2 1 1 3 3 3 0 Small membrane A-kinase anchor protein U79_P34 PF03064.16 GBG82994.1 - 2.2 7.6 15.2 4.3 6.6 15.2 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AP1AR PF15745.5 GBG82994.1 - 7.8 6.0 21.1 0.23 11.0 14.9 1.5 2 0 0 2 2 2 0 AP-1 complex-associated regulatory protein RT_RNaseH_2 PF17919.1 GBG82995.1 - 2.9e-12 46.5 0.0 8.3e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG82995.1 - 1.4e-11 44.6 0.0 4.2e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG82995.1 - 0.00013 21.9 2.7 0.00024 21.0 2.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG82995.1 - 0.02 14.8 1.6 0.053 13.5 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle L27_2 PF09045.10 GBG82995.1 - 0.61 10.1 8.2 0.29 11.1 2.3 3.0 2 0 0 2 2 2 0 L27_2 zf-CCHC_2 PF13696.6 GBG82995.1 - 0.79 9.6 4.6 1.6 8.6 4.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG82996.1 - 1.3e-18 67.4 0.0 2.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) BNR PF02012.20 GBG82997.1 - 0.35 11.0 1.7 2.8 8.3 0.2 3.5 3 0 0 3 3 3 0 BNR/Asp-box repeat zf-CCHC PF00098.23 GBG82999.1 - 3.2e-07 30.1 3.9 5.1e-07 29.5 3.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG82999.1 - 0.051 13.4 2.2 0.12 12.2 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG82999.1 - 0.27 11.1 3.4 0.56 10.1 3.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Trypsin PF00089.26 GBG83000.1 - 8.3e-33 114.0 0.0 1.2e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin CDC27 PF09507.10 GBG83001.1 - 0.1 12.0 92.3 0.12 11.7 92.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Trypsin PF00089.26 GBG83002.1 - 3.3e-39 135.0 0.0 5e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin AP3D1 PF06375.11 GBG83002.1 - 0.018 15.3 9.4 0.033 14.4 9.4 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 RNA_polI_A34 PF08208.11 GBG83002.1 - 0.097 12.7 11.7 0.2 11.7 11.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Rtf2 PF04641.12 GBG83002.1 - 0.21 10.9 8.8 0.33 10.3 8.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4604 PF15377.6 GBG83002.1 - 0.37 11.2 13.2 0.16 12.4 7.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Peptidase_S49_N PF08496.10 GBG83002.1 - 0.43 10.6 9.2 0.73 9.9 9.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NST1 PF13945.6 GBG83002.1 - 0.65 10.1 8.1 1 9.4 8.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Coilin_N PF15862.5 GBG83002.1 - 2.5 7.9 10.1 4.8 7.0 10.1 1.4 1 0 0 1 1 1 0 Coilin N-terminus BRF1 PF07741.13 GBG83002.1 - 3.1 8.2 12.5 0.27 11.6 7.6 1.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Med19 PF10278.9 GBG83002.1 - 3.4 7.6 12.5 6 6.8 12.5 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RVT_1 PF00078.27 GBG83004.1 - 5.1e-11 42.5 0.0 8.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG83004.1 - 1.6e-08 35.0 0.0 3.7e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83004.1 - 1.9e-05 25.2 0.0 3.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG83004.1 - 0.00045 20.0 0.2 0.00091 19.0 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG83004.1 - 0.0049 17.1 0.0 0.018 15.3 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG83005.1 - 4.5e-09 36.1 0.0 7.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pack_N PF02500.15 GBG83007.1 - 0.27 11.0 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Casc1_N PF15927.5 GBG83008.1 - 1.8 8.2 24.1 0.034 13.8 7.0 2.6 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 N-terminus Trypsin PF00089.26 GBG83009.1 - 3.1e-27 95.8 0.0 4.3e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin Ribosomal_L19e PF01280.20 GBG83012.1 - 5.9e-66 221.0 14.5 5.9e-66 221.0 14.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e DDE_Tnp_4 PF13359.6 GBG83014.1 - 3.7e-28 98.2 0.0 5.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83014.1 - 5.6e-10 39.2 0.0 9.1e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83014.1 - 0.00017 21.3 0.0 0.084 12.5 0.0 2.3 1 1 1 2 2 2 2 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG83015.1 - 4.1e-15 55.8 0.0 6.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83015.1 - 1e-05 25.3 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83015.1 - 5.1e-05 23.0 0.1 0.00027 20.6 0.1 2.1 2 1 0 2 2 2 1 Transposase DDE domain Trypsin PF00089.26 GBG83016.1 - 9.3e-43 146.6 0.1 2.7e-34 118.9 0.0 2.3 2 0 0 2 2 2 2 Trypsin FMN_red PF03358.15 GBG83017.1 - 0.11 12.2 0.1 21 4.8 0.0 2.5 2 0 0 2 2 2 0 NADPH-dependent FMN reductase DUF4294 PF14127.6 GBG83017.1 - 0.12 12.3 13.6 0.23 11.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4294) Replicase PF03090.17 GBG83017.1 - 0.14 12.0 0.3 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Replicase family YlbE PF14003.6 GBG83017.1 - 0.32 11.5 3.0 23 5.5 0.2 2.6 2 0 0 2 2 2 0 YlbE-like protein Chromo PF00385.24 GBG83018.1 - 0.0056 16.6 0.7 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG83018.1 - 0.066 13.5 0.0 0.066 13.5 0.0 2.9 5 0 0 5 5 5 0 Retrotransposon gag protein CBP4 PF07960.11 GBG83018.1 - 7.5 6.4 7.6 0.46 10.3 1.3 2.1 2 1 0 2 2 2 0 CBP4 DUF4407 PF14362.6 GBG83018.1 - 9.4 5.5 16.3 0.9 8.8 7.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Trypsin PF00089.26 GBG83019.1 - 2e-26 93.2 0.4 3.5e-26 92.4 0.4 1.3 1 0 0 1 1 1 1 Trypsin gag-asp_proteas PF13975.6 GBG83019.1 - 0.043 14.4 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Trypsin PF00089.26 GBG83020.1 - 4e-52 177.2 0.1 5.4e-52 176.8 0.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GBG83020.1 - 3.3e-06 28.1 0.2 6.3e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 GBG83020.1 - 0.0014 19.0 0.0 0.003 17.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) THEG PF14912.6 GBG83021.1 - 2 8.9 6.1 42 4.7 0.0 3.3 2 1 0 2 2 2 0 Testicular haploid expressed repeat RVT_1 PF00078.27 GBG83022.1 - 2.4e-09 37.1 0.0 4.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG83022.1 - 4.9e-08 33.4 0.0 9.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83022.1 - 2.7e-05 24.7 0.0 4.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG83022.1 - 0.00025 20.8 0.6 0.00045 20.0 0.6 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG83022.1 - 0.035 14.4 0.0 0.18 12.2 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease GOLD_2 PF13897.6 GBG83022.1 - 0.83 10.1 5.2 1.7 9.2 5.2 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PTPRCAP PF15713.5 GBG83022.1 - 1.6 9.0 8.3 3 8.1 8.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 GBG83022.1 - 2.3 7.9 7.3 4.2 7.0 7.3 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 GBG83022.1 - 7.1 4.8 6.7 10 4.3 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GBG83023.1 - 3 6.3 7.7 3 6.3 7.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GBG83023.1 - 3.7 5.6 20.7 4.7 5.2 20.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DDE_Tnp_4 PF13359.6 GBG83025.1 - 1.5e-14 54.0 0.1 7.5e-14 51.7 0.0 2.2 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83025.1 - 7.5e-08 32.2 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83025.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Trypsin PF00089.26 GBG83026.1 - 9.3e-24 84.5 1.9 1.3e-23 84.0 1.9 1.2 1 0 0 1 1 1 1 Trypsin FUSC PF04632.12 GBG83028.1 - 1.4 7.4 6.3 1.7 7.1 6.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FERM_M PF00373.18 GBG83028.1 - 4.5 7.7 12.4 6.3 7.2 12.0 1.5 1 1 0 1 1 1 0 FERM central domain Na_trans_assoc PF06512.13 GBG83029.1 - 2.8 8.2 12.6 5.3 7.3 12.6 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4746 PF15928.5 GBG83029.1 - 6.1 6.2 13.1 11 5.4 13.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Myb_DNA-bind_4 PF13837.6 GBG83034.1 - 2.1e-09 37.6 3.9 4e-09 36.7 2.1 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83034.1 - 7.4e-05 23.0 1.6 0.0017 18.7 0.6 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG83034.1 - 0.0021 18.2 0.7 0.0061 16.7 0.7 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG83034.1 - 0.0021 18.1 0.2 0.0056 16.7 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Metalloenzyme PF01676.18 GBG83037.1 - 2.4e-95 318.6 0.0 2.8e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 GBG83037.1 - 6.1e-58 195.8 0.0 8e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Ribosomal_L9_C PF03948.14 GBG83038.1 - 1e-20 73.9 0.8 1e-20 73.9 0.8 2.0 2 1 0 2 2 2 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 GBG83038.1 - 8e-19 66.9 0.1 1.5e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain RT_RNaseH PF17917.1 GBG83039.1 - 2.3e-43 146.8 0.0 1.5e-21 76.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83039.1 - 1.4e-33 114.9 0.0 5e-18 65.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83039.1 - 1.4e-19 70.5 0.0 2.8e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83039.1 - 7e-11 42.1 1.4 1.4e-10 41.1 0.0 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG83039.1 - 2.4e-10 40.2 0.0 5.6e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG83039.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG83040.1 - 4.3e-22 78.4 0.0 9e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83040.1 - 9.4e-20 71.1 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83040.1 - 4.1e-13 49.2 0.0 9e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83040.1 - 1.9e-11 43.9 0.7 8.6e-11 41.8 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG83040.1 - 1.5e-10 40.9 0.0 3.4e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG83040.1 - 0.0063 16.7 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger OST3_OST6 PF04756.13 GBG83042.1 - 2.2e-65 220.9 0.0 2.9e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Ribosomal_S5 PF00333.20 GBG83043.1 - 8e-30 102.6 1.1 1.5e-29 101.7 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain RT_RNaseH_2 PF17919.1 GBG83043.1 - 2.7e-27 94.7 0.0 6.5e-27 93.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83043.1 - 7.5e-27 94.3 0.1 1.1e-26 93.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83043.1 - 1.2e-26 93.0 0.0 2.4e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ribosomal_S5_C PF03719.15 GBG83043.1 - 1.8e-23 81.8 0.0 3.9e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Cwf_Cwc_15 PF04889.12 GBG83043.1 - 0.01 15.6 12.6 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MinC_C PF03775.16 GBG83044.1 - 6.5e-23 80.7 0.5 6.5e-23 80.7 0.5 1.8 2 0 0 2 2 2 1 Septum formation inhibitor MinC, C-terminal domain FapA PF03961.13 GBG83044.1 - 0.0092 14.6 0.1 0.013 14.1 0.1 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A TPR_12 PF13424.6 GBG83045.1 - 5.2e-26 90.8 30.8 7.4e-11 42.2 0.4 6.9 5 3 3 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 GBG83045.1 - 9.3e-17 59.7 27.0 0.036 14.2 0.1 8.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 GBG83045.1 - 3.1e-16 58.4 33.1 0.0011 18.7 0.1 8.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 GBG83045.1 - 1.6e-14 52.8 26.4 0.0062 16.7 0.2 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.6 GBG83045.1 - 6.6e-14 51.3 24.2 1.7e-05 24.5 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 GBG83045.1 - 1.8e-08 33.9 16.3 0.096 12.8 0.6 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 GBG83045.1 - 0.00059 20.4 6.7 0.56 10.9 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG83045.1 - 0.0013 19.3 8.6 25 6.0 0.4 7.1 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG83045.1 - 0.0088 16.4 12.4 6.4 7.4 0.1 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 GBG83045.1 - 0.013 16.1 9.9 11 6.9 0.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 GBG83045.1 - 0.029 14.1 11.7 0.21 11.2 0.4 4.0 3 1 1 5 5 5 0 26S proteasome subunit RPN7 PPR PF01535.20 GBG83045.1 - 0.12 12.6 0.7 47 4.5 0.1 4.1 3 0 0 3 3 3 0 PPR repeat ANAPC3 PF12895.7 GBG83045.1 - 1.3 9.3 7.4 12 6.2 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GBG83045.1 - 6.6 7.3 13.3 27 5.4 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG83046.1 - 2.8e-22 79.4 0.2 9.7e-22 77.6 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG83046.1 - 8.8e-06 25.9 0.1 0.01 16.1 0.0 3.6 2 0 0 2 2 2 2 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG83046.1 - 0.00017 22.1 0.0 0.00094 19.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG83046.1 - 0.00071 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83046.1 - 0.0044 17.5 0.0 0.013 16.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease AIF-MLS PF14962.6 GBG83046.1 - 3.5 7.5 8.2 7.5 6.5 8.2 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence LRR_6 PF13516.6 GBG83047.1 - 2.6e-14 52.0 14.1 0.13 12.3 0.0 9.8 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 GBG83047.1 - 2.2e-06 27.4 9.7 6.4 7.7 0.0 8.5 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_4 PF12799.7 GBG83047.1 - 3.2e-06 27.4 11.7 0.0096 16.3 0.4 6.3 6 2 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG83047.1 - 0.002 17.9 10.0 9.5 6.1 0.4 5.9 6 1 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.6 GBG83048.1 - 2.7e-14 51.9 14.1 0.13 12.3 0.0 9.8 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 GBG83048.1 - 2.2e-06 27.4 9.7 6.4 7.7 0.0 8.5 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_4 PF12799.7 GBG83048.1 - 3.2e-06 27.4 11.6 0.0096 16.3 0.4 6.3 6 2 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG83048.1 - 0.002 17.8 10.0 9.5 6.1 0.4 5.9 6 1 0 6 6 6 3 Leucine rich repeat Cyanate_lyase PF02560.14 GBG83049.1 - 1.1e-27 95.7 0.1 1.7e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Clr2_transil PF16761.5 GBG83049.1 - 0.00079 20.2 2.0 0.0097 16.7 0.7 2.4 2 0 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 gag-asp_proteas PF13975.6 GBG83050.1 - 6e-08 33.1 0.3 2.2e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83050.1 - 3.5e-05 24.4 0.3 0.00011 22.7 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG83050.1 - 0.0052 16.6 0.8 0.01 15.7 0.8 1.4 1 0 0 1 1 1 1 Aspartyl protease RXLR PF16810.5 GBG83050.1 - 0.0054 17.2 6.2 0.063 13.7 1.4 2.8 3 0 0 3 3 3 1 RXLR phytopathogen effector protein, Avirulence activity RVP PF00077.20 GBG83050.1 - 0.023 15.0 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease TMEM144 PF07857.12 GBG83051.1 - 9.5e-15 54.4 1.5 7.1e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 GBG83051.1 - 8.8e-13 48.2 7.1 1.4e-06 27.9 0.3 2.2 2 0 0 2 2 2 2 Sugar transport protein Ureide_permease PF07168.11 GBG83051.1 - 9.6e-05 21.3 6.9 0.0028 16.5 0.6 2.3 2 0 0 2 2 2 2 Ureide permease IBR PF01485.21 GBG83052.1 - 1.9e-24 85.7 36.2 2.6e-14 53.2 5.0 5.2 5 0 0 5 5 5 2 IBR domain, a half RING-finger domain Ank_3 PF13606.6 GBG83052.1 - 0.00014 22.0 0.0 3.9 8.3 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_5 PF14634.6 GBG83052.1 - 0.00037 20.4 4.4 0.00037 20.4 4.4 3.8 3 0 0 3 3 3 1 zinc-RING finger domain Ank_2 PF12796.7 GBG83052.1 - 0.0012 19.4 0.0 14 6.4 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) zf-C3HC4 PF00097.25 GBG83052.1 - 0.0027 17.6 4.4 0.0027 17.6 4.4 4.6 4 1 1 5 5 4 2 Zinc finger, C3HC4 type (RING finger) DUF4667 PF15700.5 GBG83052.1 - 0.0033 17.6 2.7 0.0033 17.6 2.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) zf-RING_UBOX PF13445.6 GBG83052.1 - 0.0041 17.1 2.3 0.0041 17.1 2.3 3.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GBG83052.1 - 0.0047 16.7 3.5 0.0047 16.7 3.5 4.6 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 GBG83052.1 - 0.0071 16.6 0.0 0.82 10.1 0.0 3.2 3 0 0 3 3 2 1 Ankyrin repeats (many copies) zf-RING_2 PF13639.6 GBG83052.1 - 0.0075 16.6 5.0 0.0075 16.6 5.0 5.2 4 1 1 5 5 5 1 Ring finger domain zf-RING_14 PF17978.1 GBG83052.1 - 0.023 15.1 1.4 0.023 15.1 1.4 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain FAM176 PF14851.6 GBG83052.1 - 0.29 10.8 5.7 0.88 9.2 5.7 1.7 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 GBG83052.1 - 0.55 9.5 14.6 0.8 9.0 6.0 2.3 2 0 0 2 2 2 0 BUD22 Auto_anti-p27 PF06677.12 GBG83052.1 - 0.59 10.3 5.5 2.4 8.4 5.5 2.1 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Pox_Ag35 PF03286.14 GBG83052.1 - 0.82 9.4 4.9 2.1 8.1 4.9 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CCDC53 PF10152.9 GBG83052.1 - 1.8 8.9 4.5 24 5.3 1.9 3.3 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 GBG83052.1 - 2.8 6.6 3.9 1.4 7.6 1.4 1.6 2 0 0 2 2 2 0 Presenilin RXT2_N PF08595.11 GBG83052.1 - 3.1 7.8 7.8 5.9 6.9 7.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleo_P87 PF07267.11 GBG83052.1 - 10 4.9 5.8 16 4.2 5.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-CCCH_4 PF18044.1 GBG83054.1 - 0.0098 15.7 1.8 0.033 14.0 1.8 2.0 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 GBG83054.1 - 0.014 15.3 1.6 0.032 14.2 1.6 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG83054.1 - 0.029 14.4 1.0 0.065 13.3 1.0 1.6 1 0 0 1 1 1 0 Zinc finger domain RT_RNaseH_2 PF17919.1 GBG83057.1 - 2e-29 101.6 0.0 3.9e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83057.1 - 6.1e-25 87.5 0.0 1.4e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83057.1 - 4.8e-17 62.2 0.0 8.2e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG83057.1 - 0.013 15.7 0.0 0.064 13.5 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein Nas2_N PF18265.1 GBG83057.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Nas2 N_terminal domain NPR3 PF03666.13 GBG83057.1 - 3 6.5 5.7 4.7 5.9 5.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RVT_1 PF00078.27 GBG83058.1 - 6.9e-35 120.6 0.1 1.1e-34 119.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83058.1 - 6.3e-28 96.7 0.0 1.9e-27 95.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83058.1 - 5e-27 94.2 0.4 1.1e-25 89.9 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83058.1 - 1.1e-17 63.9 1.1 1.1e-17 63.9 1.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG83058.1 - 2.2e-05 24.2 0.0 4.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG83058.1 - 0.0007 19.8 0.4 0.04 14.1 0.2 3.4 3 0 0 3 3 3 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG83058.1 - 0.0089 16.6 0.0 0.021 15.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF4392 PF14336.6 GBG83058.1 - 0.068 12.6 0.9 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) DUF1758 PF05585.12 GBG83058.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 GBG83059.1 - 7.6e-22 77.2 0.0 1.9e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83059.1 - 3.5e-21 75.5 0.0 6.5e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83059.1 - 1.9e-13 50.3 0.4 4.9e-13 49.0 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG83059.1 - 3.3e-08 34.0 0.0 8.3e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83059.1 - 1.6e-05 25.4 0.0 4.2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG83059.1 - 0.0013 18.5 0.1 0.0029 17.4 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG83059.1 - 0.0041 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG83059.1 - 0.39 11.0 2.1 0.71 10.1 0.8 2.3 3 0 0 3 3 3 0 H2C2 zinc finger Presenilin PF01080.17 GBG83059.1 - 1.1 8.0 3.6 2 7.1 3.6 1.3 1 0 0 1 1 1 0 Presenilin Mob_synth_C PF06463.13 GBG83060.1 - 2.1e-33 115.0 0.0 3.6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 GBG83060.1 - 1.1e-30 107.2 0.2 1.8e-30 106.5 0.2 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GBG83060.1 - 1e-07 32.3 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 GBG83060.1 - 0.0054 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DDE_Tnp_4 PF13359.6 GBG83061.1 - 7.6e-30 103.7 0.0 1.1e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83061.1 - 5.2e-17 62.1 0.0 8.2e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83061.1 - 4e-06 26.6 2.3 0.0079 15.9 0.0 2.9 2 1 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG83062.1 - 6e-06 26.5 0.6 1e-05 25.8 0.6 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG83062.1 - 0.0025 18.0 0.2 0.0054 16.9 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG83062.1 - 0.03 14.6 0.1 0.076 13.3 0.1 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain UPF0183 PF03676.14 GBG83063.1 - 1.4e-62 212.2 0.0 1.7e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) RT_RNaseH PF17917.1 GBG83064.1 - 1.7e-29 102.2 0.0 4.2e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83064.1 - 1.7e-28 98.5 0.0 5.2e-28 97.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83064.1 - 1.2e-19 70.1 0.4 2.7e-19 69.0 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG83064.1 - 3.2e-07 30.2 0.0 6.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG83064.1 - 7.4e-07 29.4 0.0 2.4e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG83064.1 - 1.6e-05 25.5 0.0 4.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG83064.1 - 0.00043 19.9 0.0 0.00086 18.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG83064.1 - 0.00068 20.2 0.0 0.0022 18.5 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG83064.1 - 0.00094 19.4 0.1 0.0025 18.0 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG83064.1 - 0.0061 16.4 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG83064.1 - 0.083 12.7 0.0 4 7.3 0.0 2.8 3 1 0 3 3 3 0 Aspartyl protease ParE_toxin PF05016.15 GBG83064.1 - 0.1 13.2 0.1 0.59 10.8 0.1 2.4 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE DRY_EERY PF09750.9 GBG83064.1 - 5.1 7.4 8.1 15 5.9 0.0 2.7 2 0 0 2 2 2 0 Alternative splicing regulator UPF0183 PF03676.14 GBG83065.1 - 1.1e-54 186.2 0.0 1.6e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) RT_RNaseH_2 PF17919.1 GBG83065.1 - 6.8e-29 99.8 0.0 1.2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83065.1 - 9.9e-29 99.7 0.1 1.7e-28 99.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83065.1 - 2.4e-14 53.2 0.1 5.4e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG83065.1 - 0.03 14.5 0.0 0.1 12.9 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG83065.1 - 0.059 13.0 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SIP1 PF04938.12 GBG83066.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) mTERF PF02536.14 GBG83066.1 - 0.064 12.2 0.3 0.42 9.5 0.0 2.0 2 0 0 2 2 2 0 mTERF Dus PF01207.17 GBG83067.1 - 1.1e-50 172.5 0.1 7.7e-40 136.9 0.0 2.6 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) MR_MLE_C PF13378.6 GBG83067.1 - 0.048 13.2 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Enolase C-terminal domain-like His_biosynth PF00977.21 GBG83067.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein SOR_SNZ PF01680.17 GBG83067.1 - 0.15 11.8 0.1 6.8 6.4 0.0 2.2 1 1 1 2 2 2 0 SOR/SNZ family Retrotrans_gag PF03732.17 GBG83069.1 - 0.0034 17.6 0.5 0.0078 16.5 0.5 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG83069.1 - 0.01 15.6 0.9 0.018 14.9 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.20 GBG83069.1 - 0.031 14.6 0.0 0.084 13.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG83069.1 - 0.036 14.6 0.0 0.083 13.5 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ku_N PF03731.15 GBG83069.1 - 0.046 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain zf-CCHC PF00098.23 GBG83069.1 - 0.11 12.6 0.6 0.2 11.8 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG83070.1 - 0.0072 16.6 0.4 0.021 15.1 0.2 1.9 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG83070.1 - 0.0084 16.1 1.6 0.014 15.3 1.6 1.3 1 0 0 1 1 1 1 Zinc knuckle TraD PF06412.11 GBG83070.1 - 0.59 10.0 3.3 14 5.6 0.0 2.8 3 0 0 3 3 3 0 Conjugal transfer protein TraD zf-CCHC PF00098.23 GBG83070.1 - 0.78 9.9 4.9 1.3 9.2 4.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG83071.1 - 1.3e-05 25.0 9.4 0.0063 16.6 2.9 2.4 2 0 0 2 2 2 2 Zinc knuckle Trans_reg_C PF00486.28 GBG83071.1 - 0.0031 17.5 0.7 0.012 15.6 0.7 2.0 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal zf-CCHC_3 PF13917.6 GBG83071.1 - 0.19 11.7 6.3 1.1 9.3 0.1 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG83071.1 - 0.35 10.6 3.5 0.24 11.2 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG83071.1 - 3.5 7.4 5.8 5 6.9 0.9 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_1 PF00078.27 GBG83073.1 - 4.7e-31 108.0 0.0 6.7e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83073.1 - 0.0015 19.2 0.0 0.0032 18.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Plavaka PF18759.1 GBG83075.1 - 5.3e-22 78.5 0.9 1e-21 77.5 0.9 1.4 1 0 0 1 1 1 1 Plavaka transposase RINGv PF12906.7 GBG83075.1 - 0.0058 16.7 1.1 0.03 14.4 1.1 2.3 1 0 0 1 1 1 1 RING-variant domain MTCP1 PF08991.10 GBG83075.1 - 0.03 14.5 0.3 0.079 13.2 0.3 1.6 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type DUF507 PF04368.13 GBG83075.1 - 0.048 13.6 0.1 2 8.3 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF507) RT_RNaseH_2 PF17919.1 GBG83078.1 - 3.6e-25 87.9 0.0 7.6e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83078.1 - 5.6e-23 81.2 0.0 9.8e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83078.1 - 6.4e-22 78.2 0.1 1.1e-21 77.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83078.1 - 3.1e-06 27.7 0.0 5.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83078.1 - 3.8e-06 27.4 0.0 7.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83078.1 - 8e-05 22.4 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83078.1 - 8.1e-05 22.4 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG83082.1 - 0.0011 18.7 0.4 0.003 17.3 0.4 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HTH_16 PF12645.7 GBG83082.1 - 0.012 15.7 0.6 6.6 6.9 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain SPATA6 PF14909.6 GBG83082.1 - 0.032 14.4 0.1 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Spermatogenesis-assoc protein 6 Mei5_like PF17021.5 GBG83082.1 - 0.034 14.2 0.2 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Putative double-strand recombination repair-like Corona_S2 PF01601.16 GBG83082.1 - 0.04 12.4 0.1 3.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein ATPase-cat_bd PF12156.8 GBG83082.1 - 0.086 13.6 0.2 7.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase Nsp1_C PF05064.13 GBG83082.1 - 0.12 12.2 0.6 39 4.1 0.0 3.1 3 0 0 3 3 3 0 Nsp1-like C-terminal region SDA1 PF05285.12 GBG83083.1 - 0.17 11.3 38.1 0.17 11.3 38.1 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG83083.1 - 0.81 7.8 40.3 0.82 7.8 40.3 1.0 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG83083.1 - 2.5 6.8 18.4 2.7 6.7 18.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 GBG83083.1 - 6.2 5.0 34.1 7.2 4.8 34.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 GBG83083.1 - 8 5.1 10.0 8.6 5.0 10.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SspB PF04386.13 GBG83083.1 - 8.5 6.3 7.7 13 5.6 7.7 1.4 1 0 0 1 1 1 0 Stringent starvation protein B DUF2914 PF11141.8 GBG83084.1 - 3.9 7.3 7.4 0.3 10.9 1.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2914) PIF1 PF05970.14 GBG83085.1 - 9.3e-73 245.5 0.0 1.6e-72 244.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Csm2_III-A PF03750.13 GBG83085.1 - 0.063 14.1 0.2 0.99 10.3 0.1 2.4 2 0 0 2 2 2 0 Csm2 Type III-A DUF659 PF04937.15 GBG83086.1 - 3.8e-09 36.6 0.0 7.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG83086.1 - 2e-05 24.3 0.1 4e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MMR1 PF08505.10 GBG83086.1 - 0.16 12.3 18.7 0.33 11.2 18.7 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Med15 PF09606.10 GBG83086.1 - 0.33 9.6 27.0 0.49 9.0 27.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ASCH PF04266.14 GBG83086.1 - 0.66 10.6 5.9 4.9 7.8 0.0 2.7 2 0 0 2 2 2 0 ASCH domain MRP-S27 PF10037.9 GBG83086.1 - 1 8.1 13.4 1.9 7.3 13.4 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 RVT_1 PF00078.27 GBG83088.1 - 0.028 14.0 0.1 2.7 7.4 0.0 3.2 4 0 0 4 4 4 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2312 PF10073.9 GBG83088.1 - 0.82 9.4 0.0 0.82 9.4 0.0 2.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF659 PF04937.15 GBG83091.1 - 4.1e-06 26.7 0.0 6.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG83093.1 - 3.9e-27 95.2 0.1 6.8e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83093.1 - 2.7e-17 62.6 0.2 1.1e-16 60.7 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG83093.1 - 9.5e-08 32.3 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG83093.1 - 0.0043 17.3 0.2 0.019 15.2 0.2 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG83095.1 - 8.7e-20 71.2 0.0 1.5e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83095.1 - 3.7e-14 52.6 0.0 2.8e-13 49.8 0.0 2.4 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83095.1 - 1.3e-05 25.5 2.0 3.2e-05 24.2 0.0 2.7 4 0 0 4 4 4 1 RNase H-like domain found in reverse transcriptase TolA_bind_tri PF16331.5 GBG83095.1 - 0.0057 16.7 4.8 0.0057 16.7 4.8 2.4 2 1 1 3 3 3 1 TolA binding protein trimerisation DUF1664 PF07889.12 GBG83095.1 - 0.015 15.3 1.8 0.031 14.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.21 GBG83095.1 - 0.017 14.7 19.3 0.5 9.9 0.0 3.1 2 1 1 3 3 3 0 Intermediate filament protein Spc29 PF17082.5 GBG83095.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 SlyX PF04102.12 GBG83095.1 - 0.037 14.6 1.7 0.037 14.6 1.7 3.6 3 1 1 4 4 4 0 SlyX YusW PF14039.6 GBG83095.1 - 0.18 12.3 1.3 1.8 9.1 0.2 2.9 2 0 0 2 2 2 0 YusW-like protein DUF3760 PF12586.8 GBG83095.1 - 0.56 10.4 3.1 7.9 6.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) Filamin PF00630.19 GBG83096.1 - 3.2e-09 37.5 0.0 9.9e-08 32.7 0.0 2.5 2 1 0 2 2 2 1 Filamin/ABP280 repeat CN_hydrolase PF00795.22 GBG83097.1 - 3.4e-70 236.3 0.0 4e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TIP41 PF04176.13 GBG83098.1 - 1.8e-51 174.1 0.1 1.7e-33 115.5 0.7 2.2 2 0 0 2 2 2 2 TIP41-like family DUF488 PF04343.13 GBG83098.1 - 4.5e-16 59.6 0.0 1.3e-07 32.3 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF488 RVT_1 PF00078.27 GBG83099.1 - 1.9e-08 34.1 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4428 PF14471.6 GBG83100.1 - 0.092 12.7 0.5 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) REF PF05755.12 GBG83101.1 - 2.9e-64 216.7 4.0 3.4e-64 216.5 4.0 1.0 1 0 0 1 1 1 1 Rubber elongation factor protein (REF) Opi1 PF08618.10 GBG83101.1 - 0.073 12.3 0.0 0.09 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 RT_RNaseH_2 PF17919.1 GBG83102.1 - 1.5e-12 47.4 0.0 4.6e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83102.1 - 0.00028 21.1 0.0 0.00095 19.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83102.1 - 0.0005 19.7 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG83102.1 - 0.089 13.1 8.8 0.64 10.3 0.1 4.1 5 0 0 5 5 5 0 Retrotransposon gag protein DUF3006 PF11213.8 GBG83102.1 - 0.66 10.2 4.9 2.6 8.4 4.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) TIG PF01833.24 GBG83103.1 - 7e-05 22.8 4.1 8.8e-05 22.5 1.9 2.1 2 0 0 2 2 2 1 IPT/TIG domain RVT_1 PF00078.27 GBG83104.1 - 2.9e-28 98.9 0.0 4.1e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83104.1 - 1.8e-18 66.4 0.0 3.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83104.1 - 2.1e-09 37.6 0.0 4.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG83104.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG83105.1 - 8.5e-30 103.9 0.1 1.3e-29 103.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83105.1 - 5.5e-08 33.4 0.0 1.6e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83105.1 - 1.7e-07 31.7 0.0 3.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG83105.1 - 2.1e-06 27.5 0.0 5.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83105.1 - 0.00015 21.6 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF4360 PF14273.6 GBG83106.1 - 1.6e-25 90.0 0.2 1.9e-25 89.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF659 PF04937.15 GBG83108.1 - 3.3e-12 46.5 0.0 5.3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4360 PF14273.6 GBG83109.1 - 8.1e-27 94.2 0.1 9.8e-27 94.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Nucleo_P87 PF07267.11 GBG83111.1 - 7.4 5.3 14.9 9.7 4.9 14.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pkinase PF00069.25 GBG83112.1 - 3.9e-70 236.2 0.0 7.2e-25 87.8 0.0 4.3 4 1 1 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83112.1 - 2.4e-64 217.1 0.0 5.5e-23 81.6 0.0 3.7 3 0 0 3 3 3 3 Protein tyrosine kinase WD40 PF00400.32 GBG83112.1 - 1.2e-15 57.6 14.1 0.19 12.7 0.0 8.5 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG83112.1 - 0.0034 17.6 1.5 0.43 10.9 0.1 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Med21 PF11221.8 GBG83112.1 - 0.024 14.9 0.2 0.024 14.9 0.2 6.7 5 1 2 7 7 7 0 Subunit 21 of Mediator complex EndoU_bacteria PF14436.6 GBG83112.1 - 0.04 14.3 0.3 0.16 12.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial EndoU nuclease LCD1 PF09798.9 GBG83113.1 - 0.018 13.6 6.1 0.024 13.2 6.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Chordopox_A30L PF06015.12 GBG83113.1 - 0.044 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Chordopoxvirus A30L protein CENP-Q PF13094.6 GBG83113.1 - 1.8 8.7 13.5 0.14 12.4 6.4 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit WDCP PF15390.6 GBG83113.1 - 2.1 6.6 5.2 1.2 7.5 3.0 1.6 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family PAN_1 PF00024.26 GBG83114.1 - 0.02 14.9 0.3 0.032 14.2 0.3 1.3 1 0 0 1 1 1 0 PAN domain PPV_E2_C PF00511.17 GBG83114.1 - 0.036 14.2 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 E2 (early) protein, C terminal CDC45 PF02724.14 GBG83114.1 - 3 6.0 9.1 3.5 5.8 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4360 PF14273.6 GBG83117.1 - 5.5e-22 78.5 0.8 2e-21 76.7 0.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) SNAPc19 PF15497.6 GBG83120.1 - 0.026 15.0 8.8 0.087 13.3 0.0 3.2 2 1 1 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF4407 PF14362.6 GBG83120.1 - 0.083 12.2 12.2 1.8 7.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CLZ PF16526.5 GBG83120.1 - 0.21 12.0 4.8 0.39 11.1 0.7 3.2 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4094 PF13334.6 GBG83120.1 - 0.54 10.7 2.9 0.54 10.7 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Baculo_PEP_C PF04513.12 GBG83120.1 - 1 9.4 7.4 0.33 11.0 0.5 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KELK PF15796.5 GBG83120.1 - 1.4 9.4 12.8 6.2 7.3 6.5 2.5 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RVT_1 PF00078.27 GBG83121.1 - 9.6e-29 100.5 0.1 1.2e-28 100.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C39 PF03412.15 GBG83122.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase C39 family UPF0016 PF01169.19 GBG83125.1 - 4e-37 126.4 16.4 6.1e-21 74.5 4.6 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2232 PF09991.9 GBG83125.1 - 0.023 13.9 0.3 0.023 13.9 0.3 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) SDA1 PF05285.12 GBG83126.1 - 0.00054 19.5 21.1 0.001 18.6 21.1 1.4 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG83126.1 - 0.36 9.0 33.9 0.49 8.5 33.9 1.1 1 0 0 1 1 1 0 Nop14-like family TMEM171 PF15471.6 GBG83126.1 - 0.37 9.7 3.5 0.24 10.4 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein family 171 Tim54 PF11711.8 GBG83126.1 - 3.8 6.2 13.5 6.5 5.4 13.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Cwf_Cwc_15 PF04889.12 GBG83126.1 - 6.8 6.3 27.2 15 5.2 27.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF913 PF06025.12 GBG83126.1 - 8.2 5.3 5.0 15 4.5 5.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) zf-CCHC PF00098.23 GBG83127.1 - 2.8e-07 30.3 2.9 5.2e-07 29.5 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG83127.1 - 0.026 14.3 3.4 0.048 13.5 3.4 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG83127.1 - 0.48 10.4 4.3 0.34 10.9 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle BT1 PF03092.16 GBG83127.1 - 6.4 4.9 7.5 8.2 4.5 7.5 1.1 1 0 0 1 1 1 0 BT1 family ThiI PF02568.14 GBG83128.1 - 0.0063 16.1 0.0 0.042 13.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Lum_binding PF00677.17 GBG83129.1 - 8.6e-46 153.8 1.5 8e-23 80.2 0.5 2.2 2 0 0 2 2 2 2 Lumazine binding domain LVIVD PF08309.11 GBG83129.1 - 0.022 14.1 0.6 0.046 13.0 0.1 1.8 2 0 0 2 2 2 0 LVIVD repeat cobW PF02492.19 GBG83130.1 - 7.6e-51 172.2 0.4 7.6e-51 172.2 0.4 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GBG83130.1 - 6.8e-16 58.0 0.0 1.4e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 GBG83130.1 - 0.0035 17.8 0.3 0.041 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.18 GBG83130.1 - 0.0038 16.8 1.1 0.013 15.0 0.2 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GBG83130.1 - 0.0064 16.4 3.4 0.45 10.4 0.1 2.8 3 0 0 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 GBG83130.1 - 0.0094 15.8 0.6 0.049 13.4 0.6 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein TsaE PF02367.17 GBG83130.1 - 0.016 15.2 0.1 0.058 13.4 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 GBG83130.1 - 0.022 14.5 0.2 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 GBG83130.1 - 0.022 14.3 5.8 0.38 10.3 1.4 3.3 3 1 1 4 4 4 0 Elongation factor Tu GTP binding domain Com_YlbF PF06133.11 GBG83130.1 - 0.029 15.0 0.6 0.029 15.0 0.6 2.8 3 0 0 3 3 2 0 Control of competence regulator ComK, YlbF/YmcA T2SSE PF00437.20 GBG83130.1 - 0.042 12.9 0.0 0.083 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 GBG83130.1 - 0.047 13.8 0.0 0.17 12.0 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 GBG83130.1 - 0.069 13.7 0.1 0.069 13.7 0.1 3.4 2 1 0 2 2 1 0 AAA domain Arf PF00025.21 GBG83130.1 - 0.1 12.0 0.4 2.4 7.6 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 GBG83130.1 - 0.28 11.4 1.0 0.69 10.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain MarC PF01914.17 GBG83130.1 - 0.72 9.2 0.0 0.72 9.2 0.0 2.1 3 0 0 3 3 2 0 MarC family integral membrane protein SDA1 PF05285.12 GBG83130.1 - 3.8 6.8 42.1 0.38 10.1 16.4 2.2 2 0 0 2 2 2 0 SDA1 TPR_19 PF14559.6 GBG83131.1 - 4.3e-21 75.2 4.7 2.8e-05 24.5 0.0 7.0 3 2 4 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 GBG83131.1 - 6.2e-18 63.4 15.3 0.42 10.8 0.0 11.3 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 GBG83131.1 - 5.2e-16 58.1 6.6 0.014 16.0 0.0 9.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 GBG83131.1 - 9.3e-14 50.4 14.7 0.57 10.3 0.0 11.1 13 0 0 13 13 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 GBG83131.1 - 2.2e-13 49.6 5.8 0.00027 20.6 0.1 5.8 6 0 0 6 6 6 3 TPR repeat TPR_8 PF13181.6 GBG83131.1 - 5e-13 48.1 9.3 1.1 9.7 0.0 8.9 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 GBG83131.1 - 5.2e-12 46.2 30.2 0.014 16.0 0.0 8.7 8 1 2 10 10 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 GBG83131.1 - 2.7e-11 42.8 13.4 3 7.8 0.1 10.0 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_9 PF13371.6 GBG83131.1 - 4.7e-11 42.7 10.9 1.8e-05 24.8 0.9 6.2 4 1 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG83131.1 - 6.3e-11 41.9 2.4 0.88 10.1 0.0 7.0 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 GBG83131.1 - 1e-10 41.7 22.5 0.19 12.0 0.0 10.8 8 3 2 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG83131.1 - 2.4e-10 40.3 28.7 0.023 15.5 0.0 11.7 9 2 3 12 12 11 2 Tetratricopeptide repeat TPR_20 PF14561.6 GBG83131.1 - 1.2e-07 32.0 9.4 0.49 10.8 0.2 5.7 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 GBG83131.1 - 2.2e-07 30.4 7.4 0.0021 17.3 0.3 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG83131.1 - 4.1e-07 30.1 14.7 0.0012 19.0 0.1 5.2 6 0 0 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GBG83131.1 - 5.6e-06 26.0 9.5 13 5.9 0.0 9.1 8 0 0 8 8 8 0 Tetratricopeptide repeat NARP1 PF12569.8 GBG83131.1 - 0.00094 18.2 1.9 0.78 8.6 0.0 3.9 2 1 2 4 4 4 2 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.6 GBG83131.1 - 0.0029 18.0 7.8 2.2 8.7 0.1 4.1 5 0 0 5 5 4 1 Alkyl sulfatase dimerisation DUF2989 PF11207.8 GBG83131.1 - 0.086 12.6 0.6 7.3 6.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2989) ChAPs PF09295.10 GBG83131.1 - 0.11 11.5 0.8 2.1 7.2 0.1 2.5 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) BAF1_ABF1 PF04684.13 GBG83131.1 - 0.26 10.3 3.9 0.46 9.5 3.9 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TPPII_N PF12583.8 GBG83131.1 - 0.51 10.9 7.2 4.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Pkinase PF00069.25 GBG83132.1 - 9.1e-24 84.2 0.0 2.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83132.1 - 2.4e-22 79.5 0.1 4.1e-21 75.4 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase RVT_1 PF00078.27 GBG83132.1 - 1.4e-06 28.0 0.2 0.00059 19.4 0.2 3.6 3 1 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2730 PF10805.8 GBG83132.1 - 4.9 7.3 11.0 0.71 10.0 1.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) WD40 PF00400.32 GBG83133.1 - 2.2e-13 50.4 9.4 0.00056 20.7 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG83133.1 - 8.8e-06 25.9 1.6 0.17 12.2 0.0 4.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG83133.1 - 4.4e-05 22.3 0.3 0.083 11.5 0.1 3.4 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 GBG83133.1 - 0.022 14.6 0.0 0.28 11.0 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4047 PF13256.6 GBG83133.1 - 0.064 13.4 0.3 0.19 11.9 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) RVT_1 PF00078.27 GBG83134.1 - 7.7e-39 133.5 0.0 1.1e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG83135.1 - 2e-22 79.8 0.0 3.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83135.1 - 4.9e-21 75.3 0.0 1.2e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG83135.1 - 0.00025 21.8 0.2 0.41 11.6 0.0 3.7 4 0 0 4 4 3 1 WD domain, G-beta repeat Csm1_N PF18504.1 GBG83135.1 - 0.0058 16.9 6.2 0.0058 16.9 6.2 3.1 2 1 1 3 3 3 1 Csm1 N-terminal domain ANAPC4_WD40 PF12894.7 GBG83135.1 - 0.07 13.4 0.1 2.4 8.5 0.0 3.3 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain GAS PF13851.6 GBG83135.1 - 0.3 10.4 23.6 0.24 10.7 7.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nuc_N PF14448.6 GBG83135.1 - 0.37 10.7 2.2 10 6.1 0.0 3.4 2 1 1 3 3 3 0 Nuclease N terminal DUF4472 PF14739.6 GBG83135.1 - 0.55 11.0 16.0 0.063 14.0 3.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) bZIP_1 PF00170.21 GBG83135.1 - 1.4 9.1 19.1 1 9.5 1.7 4.1 4 1 1 5 5 4 0 bZIP transcription factor Spc24 PF08286.11 GBG83135.1 - 1.5 9.1 16.1 3.6 7.9 3.2 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF812 PF05667.11 GBG83135.1 - 2.4 7.0 22.4 15 4.3 22.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ZapB PF06005.12 GBG83135.1 - 3.6 8.1 20.9 9.1 6.8 7.5 2.9 2 1 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 GBG83135.1 - 4.2 7.5 18.3 7.6 6.7 7.2 2.8 2 1 0 2 2 2 0 Basic region leucine zipper CENP-F_leu_zip PF10473.9 GBG83135.1 - 5 7.2 24.5 0.34 10.9 8.3 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 GBG83135.1 - 5.9 7.0 24.6 6.2 6.9 5.5 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 GBG83135.1 - 5.9 5.7 22.4 11 4.8 22.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 GBG83135.1 - 7.1 6.5 17.2 1.4 8.7 3.6 2.5 2 0 0 2 2 2 0 Septum formation initiator Cluap1 PF10234.9 GBG83135.1 - 7.9 5.8 20.9 5.1 6.4 9.4 2.4 1 1 1 2 2 2 0 Clusterin-associated protein-1 BSP_II PF05432.11 GBG83136.1 - 0.0017 18.1 7.7 0.0017 18.1 7.7 3.1 2 1 1 3 3 1 1 Bone sialoprotein II (BSP-II) SpoIIP PF07454.11 GBG83136.1 - 0.0093 15.4 19.8 0.22 10.9 13.9 2.1 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) FAM176 PF14851.6 GBG83136.1 - 0.021 14.5 2.7 0.021 14.5 2.7 3.3 2 1 0 2 2 1 0 FAM176 family MAM33 PF02330.16 GBG83136.1 - 0.028 14.4 0.7 0.028 14.4 0.7 3.1 2 1 1 3 3 1 0 Mitochondrial glycoprotein Tim54 PF11711.8 GBG83136.1 - 0.031 13.1 24.5 0.02 13.7 13.0 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FYDLN_acid PF09538.10 GBG83136.1 - 0.05 14.3 0.8 0.05 14.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SAPS PF04499.15 GBG83136.1 - 0.064 12.0 14.9 0.087 11.6 14.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Connexin PF00029.19 GBG83136.1 - 0.077 12.7 21.1 0.67 9.7 0.9 2.2 2 0 0 2 2 2 0 Connexin PPP4R2 PF09184.11 GBG83136.1 - 0.2 11.2 41.3 0.64 9.6 26.4 2.4 2 0 0 2 2 2 0 PPP4R2 TRAP_alpha PF03896.16 GBG83136.1 - 0.24 10.6 28.6 0.29 10.3 16.2 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 GBG83136.1 - 0.27 9.5 47.2 0.099 10.9 10.2 2.1 2 0 0 2 2 2 0 CDC45-like protein SARAF PF06682.12 GBG83136.1 - 0.29 10.7 11.6 0.38 10.3 11.6 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Vfa1 PF08432.10 GBG83136.1 - 0.33 11.3 29.7 1.2 9.4 2.8 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF5427 PF10310.9 GBG83136.1 - 0.34 9.8 23.9 0.48 9.3 14.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Maf1 PF09174.10 GBG83136.1 - 0.36 11.0 0.1 0.36 11.0 0.1 2.2 2 0 0 2 2 1 0 Maf1 regulator Cwf_Cwc_15 PF04889.12 GBG83136.1 - 0.53 10.0 38.4 0.92 9.2 6.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG83136.1 - 0.75 7.9 56.5 0.039 12.2 35.1 2.1 2 0 0 2 2 2 0 Nop14-like family DUF3169 PF11368.8 GBG83136.1 - 0.81 9.2 0.0 0.81 9.2 0.0 3.3 2 1 0 2 2 1 0 Protein of unknown function (DUF3169) AIF_C PF14721.6 GBG83136.1 - 0.86 10.0 15.3 4.3 7.7 9.9 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Afi1 PF07792.12 GBG83136.1 - 0.87 10.1 29.2 3.3 8.2 1.8 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peroxin-13_N PF04088.13 GBG83136.1 - 1.3 9.3 5.6 4.9 7.4 0.5 2.6 2 1 0 2 2 2 0 Peroxin 13, N-terminal region DUF4471 PF14740.6 GBG83136.1 - 3 7.0 16.7 4.2 6.5 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DUF5523 PF17661.1 GBG83136.1 - 3.1 7.4 45.6 0.2 11.3 3.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) IDO PF01231.18 GBG83136.1 - 3.4 6.3 13.9 2 7.1 5.3 2.2 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase CobT PF06213.12 GBG83136.1 - 3.7 6.8 56.0 0.042 13.2 4.3 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT BSMAP PF12280.8 GBG83136.1 - 4 7.6 6.2 2.8 8.1 1.3 2.2 2 0 0 2 2 2 0 Brain specific membrane anchored protein CLN3 PF02487.17 GBG83136.1 - 4.2 6.3 10.5 30 3.5 8.4 2.0 2 0 0 2 2 2 0 CLN3 protein DNA_pol_phi PF04931.13 GBG83136.1 - 4.4 5.3 59.9 2.8 5.9 40.6 2.0 2 0 0 2 2 2 0 DNA polymerase phi AAA_23 PF13476.6 GBG83136.1 - 5.6 7.4 25.0 1.4 9.4 12.9 2.2 2 0 0 2 2 2 0 AAA domain Paf1 PF03985.13 GBG83136.1 - 6.4 5.7 67.5 4.4 6.2 18.6 2.1 1 1 1 2 2 2 0 Paf1 AAR2 PF05282.11 GBG83136.1 - 7 5.9 11.6 1.4 8.2 4.5 2.0 2 0 0 2 2 2 0 AAR2 protein DUF3391 PF11871.8 GBG83136.1 - 7.8 7.0 21.1 8.6 6.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) PIP5K PF01504.18 GBG83136.1 - 9.6 5.3 13.3 4.2 6.5 6.9 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.32 GBG83137.1 - 0.062 14.2 0.1 41 5.3 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat RT_RNaseH_2 PF17919.1 GBG83138.1 - 3e-27 94.6 0.0 7.9e-27 93.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83138.1 - 3.1e-27 95.6 0.2 5.7e-27 94.7 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83138.1 - 5.7e-21 74.8 0.0 1.3e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG83138.1 - 9.3e-07 29.3 0.0 2.5e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83138.1 - 2.2e-06 28.2 0.0 5.8e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83138.1 - 0.001 18.8 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83138.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Prothymosin PF03247.14 GBG83139.1 - 0.035 14.6 30.3 0.81 10.2 23.3 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Hid1 PF12722.7 GBG83139.1 - 9.2 4.2 6.3 11 4.0 6.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.25 GBG83140.1 - 1.7e-38 132.5 0.0 3.6e-38 131.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83140.1 - 4.5e-23 81.9 0.0 1.2e-13 51.0 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 GBG83140.1 - 0.035 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GBG83140.1 - 0.04 12.7 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RT_RNaseH PF17917.1 GBG83141.1 - 1.3e-24 86.5 0.0 1.2e-23 83.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83141.1 - 1.6e-24 85.8 0.0 4.1e-24 84.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83141.1 - 5.1e-24 85.0 0.0 1.1e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83141.1 - 1.2e-05 25.8 0.0 0.15 12.8 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG83141.1 - 0.00054 20.5 0.0 0.033 14.7 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease dCache_1 PF02743.18 GBG83141.1 - 0.0049 16.7 0.1 0.0093 15.8 0.1 1.4 1 0 0 1 1 1 1 Cache domain Syndecan PF01034.20 GBG83141.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Asp_protease PF09668.10 GBG83141.1 - 0.072 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Rax2 PF12768.7 GBG83141.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RT_RNaseH PF17917.1 GBG83142.1 - 1.3e-24 86.5 0.0 1.2e-23 83.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83142.1 - 1.6e-24 85.9 0.0 4e-24 84.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83142.1 - 4.9e-24 85.1 0.0 1.1e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83142.1 - 1.2e-05 25.8 0.0 0.14 12.8 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG83142.1 - 0.00052 20.5 0.0 0.033 14.7 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease dCache_1 PF02743.18 GBG83142.1 - 0.0049 16.7 0.1 0.0092 15.8 0.1 1.4 1 0 0 1 1 1 1 Cache domain Asp_protease PF09668.10 GBG83142.1 - 0.079 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG83143.1 - 2.1e-20 73.2 0.0 3.8e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG83143.1 - 3.2e-09 36.7 0.0 5.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83143.1 - 4.3e-07 30.5 0.0 1.1e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83143.1 - 4.7e-05 23.9 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG83143.1 - 0.047 13.6 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG83143.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease APG6_N PF17675.1 GBG83143.1 - 0.85 10.1 13.2 0.5 10.9 6.3 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Tudor-knot PF11717.8 GBG83144.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain TFIIA PF03153.13 GBG83145.1 - 0.81 9.6 43.3 1.2 9.1 43.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH_2 PF17919.1 GBG83146.1 - 2.8e-26 91.5 0.0 7.2e-26 90.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83146.1 - 6.7e-26 90.6 0.0 2.2e-25 89.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83146.1 - 1.9e-13 50.4 0.0 4e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Es2 PF09751.9 GBG83146.1 - 0.0016 18.3 14.7 0.0024 17.7 14.7 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 Phage_GPO PF05929.11 GBG83146.1 - 0.25 10.9 0.1 0.25 10.9 0.1 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Pkinase PF00069.25 GBG83150.1 - 5.1e-48 163.7 0.0 8.1e-48 163.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83150.1 - 4.3e-27 95.0 0.0 4.6e-14 52.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 GBG83150.1 - 0.051 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GBG83151.1 - 1.1e-17 64.3 0.0 1.4e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83151.1 - 1.7e-08 34.1 0.0 2.3e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83152.1 - 7.1e-27 94.4 0.0 1.6e-26 93.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83152.1 - 6.3e-16 58.4 0.0 3.1e-11 43.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 GBG83152.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GBG83152.1 - 0.018 13.8 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 GBG83152.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 GBG83153.1 - 3.7e-47 160.9 0.0 1e-46 159.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83153.1 - 6.9e-26 91.1 0.0 9.1e-13 48.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 GBG83153.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GBG83153.1 - 0.25 10.1 0.0 0.37 9.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DDE_Tnp_4 PF13359.6 GBG83154.1 - 2.5e-20 72.8 0.0 5.7e-20 71.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83154.1 - 6e-07 29.3 0.0 9.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83154.1 - 0.029 14.0 0.1 0.26 10.9 0.0 2.4 3 0 0 3 3 3 0 Transposase DDE domain RVT_1 PF00078.27 GBG83155.1 - 2e-29 102.7 0.0 4.7e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83155.1 - 8.7e-25 86.7 0.0 1.9e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83155.1 - 1.3e-23 83.3 0.0 3.9e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83155.1 - 1.1e-18 67.1 0.3 2.3e-18 66.0 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83155.1 - 2.5e-08 34.1 0.0 8.1e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG83155.1 - 0.00083 19.6 0.1 0.0075 16.5 0.1 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG83155.1 - 0.002 18.3 0.0 0.0046 17.1 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF4187 PF13821.6 GBG83155.1 - 0.049 13.4 0.9 0.2 11.5 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) APG17 PF04108.12 GBG83155.1 - 0.2 10.7 0.7 0.5 9.4 0.1 1.8 2 0 0 2 2 2 0 Autophagy protein Apg17 Apolipoprotein PF01442.18 GBG83156.1 - 1.8e-19 70.4 98.7 3.1e-08 33.7 30.4 6.6 3 1 3 7 7 7 5 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GBG83156.1 - 1.4e-15 57.6 118.8 0.031 14.8 11.5 11.2 4 2 6 10 10 10 6 YtxH-like protein DUF883 PF05957.13 GBG83156.1 - 1.2e-06 29.0 104.0 0.022 15.3 6.0 11.1 5 2 6 11 11 11 5 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 GBG83156.1 - 2e-06 28.0 58.6 0.064 13.4 3.6 6.1 4 1 2 6 6 6 5 Apolipophorin-III precursor (apoLp-III) LEA_4 PF02987.16 GBG83156.1 - 7.6e-06 25.9 32.3 0.00029 20.9 11.9 13.8 5 1 9 14 14 14 4 Late embryogenesis abundant protein Baculo_PEP_C PF04513.12 GBG83156.1 - 0.0073 16.3 0.6 49 4.0 0.0 4.4 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 GBG83156.1 - 0.038 13.9 19.2 1.4 8.9 0.2 6.1 4 2 2 6 6 6 0 Apolipoprotein O UPF0181 PF03701.14 GBG83156.1 - 0.67 9.6 3.0 2 8.1 3.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Matrilin_ccoil PF10393.9 GBG83156.1 - 2.1 8.3 4.7 17 5.3 0.5 3.0 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin LXG PF04740.12 GBG83156.1 - 3.1 7.4 34.3 0.19 11.4 8.5 4.5 3 1 1 4 4 4 0 LXG domain of WXG superfamily Prominin PF05478.11 GBG83156.1 - 6.3 4.6 23.2 0.08 10.9 10.1 2.9 3 1 0 3 3 3 0 Prominin Pkinase PF00069.25 GBG83157.1 - 1.5e-46 158.9 0.0 2.7e-46 158.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83157.1 - 7.4e-25 87.7 0.0 1.3e-12 47.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 GBG83157.1 - 0.045 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GBG83157.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 GBG83157.1 - 0.19 11.0 0.1 18 4.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Myb_DNA-bind_4 PF13837.6 GBG83158.1 - 9.9e-08 32.3 10.4 2.1e-07 31.2 3.7 3.2 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83158.1 - 0.002 18.4 3.7 0.021 15.1 2.5 2.9 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase PF00069.25 GBG83159.1 - 2.1e-47 161.7 0.0 2.9e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83159.1 - 1.3e-25 90.1 0.0 2.1e-24 86.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GBG83159.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.12 GBG83163.1 - 0.0034 15.7 14.0 0.0035 15.6 14.0 1.1 1 0 0 1 1 1 1 Nop14-like family LAP1C PF05609.12 GBG83163.1 - 0.08 12.0 6.3 0.093 11.8 6.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 GBG83163.1 - 0.17 10.2 11.8 0.19 10.0 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 GBG83163.1 - 0.2 11.4 9.4 0.32 10.7 9.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.15 GBG83163.1 - 0.67 8.7 5.7 0.82 8.4 5.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 GBG83163.1 - 0.95 8.2 5.6 1.1 8.0 5.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spore_coat_CotO PF14153.6 GBG83163.1 - 2.1 8.2 8.4 4.3 7.2 8.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO RNA_pol_3_Rpc31 PF11705.8 GBG83163.1 - 3 8.0 22.0 8.4 6.6 22.0 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Presenilin PF01080.17 GBG83163.1 - 5 5.8 5.1 5.5 5.6 5.1 1.1 1 0 0 1 1 1 0 Presenilin DUF2457 PF10446.9 GBG83163.1 - 8.8 5.3 23.0 13 4.8 23.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 GBG83164.1 - 0.0025 17.2 15.4 0.0041 16.5 15.4 1.4 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 GBG83164.1 - 0.0037 16.8 21.8 0.0073 15.8 21.8 1.5 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG83164.1 - 0.024 13.0 12.0 0.033 12.5 12.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 GBG83164.1 - 0.036 13.9 5.0 0.065 13.1 5.0 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein NPR3 PF03666.13 GBG83164.1 - 0.073 11.9 2.6 0.12 11.2 2.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 GBG83164.1 - 0.075 12.5 7.5 0.14 11.6 7.5 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Plasmodium_Vir PF05795.11 GBG83164.1 - 0.15 11.5 3.4 0.29 10.5 3.4 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 GBG83164.1 - 0.77 8.5 6.1 1.2 7.8 6.1 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GBG83164.1 - 2 7.5 3.3 3 7.0 3.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 GBG83164.1 - 2 6.5 33.4 3.2 5.9 33.4 1.3 1 0 0 1 1 1 0 Nop14-like family Connexin PF00029.19 GBG83164.1 - 3.4 7.4 5.3 7.5 6.2 5.3 1.6 1 0 0 1 1 1 0 Connexin Serglycin PF04360.12 GBG83165.1 - 1.7 8.6 0.0 1.7 8.6 0.0 3.8 2 1 2 4 4 4 0 Serglycin Pkinase PF00069.25 GBG83166.1 - 2e-32 112.6 0.0 7.9e-31 107.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83166.1 - 1.6e-16 60.4 0.0 4.2e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase GATase_6 PF13522.6 GBG83167.1 - 4.7e-08 33.3 0.0 8.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GBG83167.1 - 3.4e-05 22.9 0.1 0.00053 19.0 0.0 2.5 3 0 0 3 3 3 1 Glutamine amidotransferases class-II RVT_1 PF00078.27 GBG83168.1 - 3e-31 108.7 0.1 4.5e-31 108.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83168.1 - 1.4e-27 95.6 0.4 1.1e-13 51.1 0.0 3.3 3 0 0 3 3 3 2 Integrase zinc binding domain rve PF00665.26 GBG83168.1 - 1.8e-15 57.1 0.0 3.7e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain Chromo PF00385.24 GBG83168.1 - 1.5e-09 37.7 0.0 3.8e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG83168.1 - 6.3e-09 35.9 0.2 0.00051 20.2 0.0 2.7 2 0 0 2 2 2 2 H2C2 zinc finger Trypsin PF00089.26 GBG83171.1 - 0.0033 17.3 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin Zip PF02535.22 GBG83171.1 - 1.9 7.6 4.2 2.8 7.1 4.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Chromo PF00385.24 GBG83172.1 - 2.1e-12 46.7 0.0 3.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG83174.1 - 0.14 12.5 8.4 0.15 12.4 0.3 3.4 4 1 0 4 4 4 0 Retrotransposon gag protein KfrA_N PF11740.8 GBG83174.1 - 3 8.6 19.7 5 7.8 7.6 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term RVT_1 PF00078.27 GBG83175.1 - 4.4e-19 68.9 0.0 8.2e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG83175.1 - 1.9e-10 40.6 0.0 3.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 GBG83175.1 - 1.2e-09 38.3 0.0 6.5e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG83175.1 - 1.1e-06 29.0 0.0 2.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83175.1 - 4.8e-06 27.1 0.0 1.2e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83175.1 - 2.2e-05 24.3 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Plant_tran PF04827.14 GBG83175.1 - 0.0001 22.0 0.0 0.00039 20.1 0.0 1.8 1 1 0 1 1 1 1 Plant transposon protein Chromo PF00385.24 GBG83175.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG83175.1 - 0.00052 19.8 0.0 0.00097 18.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Jas PF16135.5 GBG83175.1 - 0.37 11.0 4.1 3.8 7.8 0.4 3.3 4 0 0 4 4 4 0 TPL-binding domain in jasmonate signalling Myb_DNA-bind_4 PF13837.6 GBG83176.1 - 5.5e-08 33.1 0.9 5.5e-08 33.1 0.9 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG83176.1 - 0.062 13.6 1.0 0.26 11.6 1.0 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Trypsin PF00089.26 GBG83177.1 - 1.3e-43 149.4 0.0 2e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Retrotrans_gag PF03732.17 GBG83180.1 - 0.0014 18.8 0.1 0.0014 18.8 0.1 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein Tudor-knot PF11717.8 GBG83180.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Ribosomal_L34 PF00468.17 GBG83181.1 - 0.43 10.6 0.0 0.43 10.6 0.0 3.2 3 0 0 3 3 3 0 Ribosomal protein L34 Menin PF05053.13 GBG83181.1 - 3.4 5.9 7.1 3.9 5.7 7.1 1.1 1 0 0 1 1 1 0 Menin Trypsin PF00089.26 GBG83182.1 - 5.3e-46 157.2 0.2 8.4e-46 156.5 0.2 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 GBG83182.1 - 0.00084 19.7 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 GBG83182.1 - 0.0026 18.7 0.1 0.0063 17.4 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Maf_N PF08383.11 GBG83184.1 - 0.31 10.8 1.9 0.43 10.4 0.5 2.1 2 0 0 2 2 2 0 Maf N-terminal region DUF659 PF04937.15 GBG83185.1 - 3.5e-14 52.9 0.0 1.7e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG83185.1 - 7.5e-10 38.5 0.6 2.6e-09 36.7 0.2 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region FYVE PF01363.21 GBG83186.1 - 5.5e-16 58.5 8.9 1.3e-15 57.3 8.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger Ank_4 PF13637.6 GBG83186.1 - 5.1e-09 36.5 0.0 4e-06 27.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GBG83186.1 - 6.5e-09 36.3 0.0 1.1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GBG83186.1 - 2.5e-06 27.7 0.1 6.6e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG83186.1 - 4.6e-05 23.5 0.0 0.011 16.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 GBG83186.1 - 0.00012 22.3 0.0 0.00058 20.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat zf-CCHC PF00098.23 GBG83187.1 - 0.00015 21.6 2.3 0.00025 21.0 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG83187.1 - 0.0041 16.9 1.9 0.0063 16.3 1.9 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF3394 PF11874.8 GBG83187.1 - 0.2 11.3 3.8 0.33 10.6 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) SAGA-Tad1 PF12767.7 GBG83187.1 - 2.3 7.9 13.7 3.2 7.4 13.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit OmpH PF03938.14 GBG83187.1 - 5.8 7.3 22.4 8.5 6.7 22.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 GBG83187.1 - 9.2 4.7 8.9 11 4.3 8.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ArAE_2_N PF10337.9 GBG83187.1 - 9.9 5.1 6.4 12 4.7 6.4 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF4708 PF15813.5 GBG83188.1 - 2.8e-05 23.4 0.1 4.6e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4708) RVT_1 PF00078.27 GBG83189.1 - 1.9e-37 128.9 0.0 3e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG83190.1 - 2.2e-05 24.8 0.1 3.8e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG83190.1 - 0.00085 19.3 0.1 0.0012 18.8 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Beta_helix PF13229.6 GBG83191.1 - 1.4e-06 28.3 1.1 0.02 14.8 0.0 2.2 1 1 1 2 2 2 2 Right handed beta helix region Palm_thioest PF02089.15 GBG83191.1 - 0.016 15.1 0.1 0.02 14.7 0.1 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase ArsC PF03960.15 GBG83191.1 - 0.2 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 ArsC family NosD PF05048.13 GBG83191.1 - 0.36 10.0 1.5 0.85 8.8 1.6 1.6 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 GBG83191.1 - 4 8.1 15.8 16 6.2 0.0 5.9 6 1 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF5123 PF17161.4 GBG83191.1 - 6.7 7.8 10.7 3.4e+02 2.3 10.4 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5123) Beta_helix PF13229.6 GBG83192.1 - 9.2e-15 54.8 22.9 9.2e-09 35.3 11.3 3.4 3 1 0 3 3 3 2 Right handed beta helix region NosD PF05048.13 GBG83192.1 - 0.0038 16.5 15.6 0.11 11.7 1.0 2.8 2 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) OmpW PF03922.14 GBG83192.1 - 0.055 13.3 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 OmpW family Noggin PF05806.12 GBG83192.1 - 0.33 10.8 1.6 0.56 10.1 1.6 1.2 1 0 0 1 1 1 0 Noggin DUF5123 PF17161.4 GBG83192.1 - 0.43 11.7 14.7 21 6.2 0.0 4.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5123) Beta_helix PF13229.6 GBG83193.1 - 9.2e-15 54.8 22.9 9.2e-09 35.3 11.3 3.4 3 1 0 3 3 3 2 Right handed beta helix region NosD PF05048.13 GBG83193.1 - 0.0038 16.5 15.6 0.11 11.7 1.0 2.8 2 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) OmpW PF03922.14 GBG83193.1 - 0.055 13.3 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 OmpW family Noggin PF05806.12 GBG83193.1 - 0.33 10.8 1.6 0.56 10.1 1.6 1.2 1 0 0 1 1 1 0 Noggin DUF5123 PF17161.4 GBG83193.1 - 0.43 11.7 14.7 21 6.2 0.0 4.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5123) Beta_helix PF13229.6 GBG83194.1 - 7e-14 52.0 26.6 6.4e-08 32.6 14.4 3.4 2 2 1 3 3 3 3 Right handed beta helix region NosD PF05048.13 GBG83194.1 - 0.0022 17.3 15.5 0.087 12.1 0.9 2.8 2 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) OmpW PF03922.14 GBG83194.1 - 0.041 13.7 0.1 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 OmpW family DUF5123 PF17161.4 GBG83194.1 - 0.15 13.1 14.3 18 6.5 0.0 4.8 3 1 0 3 3 3 0 Domain of unknown function (DUF5123) DUF4957 PF16318.5 GBG83195.1 - 0.04 13.8 2.1 4 7.4 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4957) BatA PF07584.11 GBG83195.1 - 0.045 14.1 1.2 0.11 12.9 1.2 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal NosD PF05048.13 GBG83195.1 - 0.14 11.4 15.9 1 8.5 7.6 3.3 2 2 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Peptidase_C48 PF02902.19 GBG83198.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Histone PF00125.24 GBG83199.1 - 1.7e-18 67.2 3.0 4.9e-18 65.8 3.0 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-FPG_IleRS PF06827.14 GBG83199.1 - 0.3 11.0 2.9 5.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Topo_Zn_Ribbon PF08272.11 GBG83200.1 - 0.019 14.6 0.3 0.037 13.7 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like FAD_binding_6 PF00970.24 GBG83201.1 - 3.9e-30 104.1 0.0 6.6e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GBG83201.1 - 2.1e-26 92.7 0.0 4.2e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 GBG83201.1 - 1.2e-17 63.8 0.1 9.5e-14 51.3 0.0 2.7 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 GBG83201.1 - 0.0029 17.7 0.0 0.0081 16.3 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Mo-co_dimer PF03404.16 GBG83201.1 - 0.035 14.1 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Keratin_2_head PF16208.5 GBG83201.1 - 0.12 12.5 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Keratin type II head Asp_protease_2 PF13650.6 GBG83202.1 - 5.5e-08 33.3 0.0 1.8e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83202.1 - 1.6e-06 28.6 0.0 3.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG83202.1 - 7.7e-05 22.5 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG83202.1 - 0.00019 21.0 0.1 0.00042 19.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG83202.1 - 0.00023 21.0 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG83202.1 - 0.0023 18.1 0.0 0.0064 16.7 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Oxidored_molyb PF00174.19 GBG83203.1 - 1.3e-57 194.2 0.0 1.6e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Intimin_C PF07979.11 GBG83204.1 - 0.17 12.3 0.1 0.36 11.3 0.1 1.6 1 0 0 1 1 1 0 Intimin C-type lectin domain HLH PF00010.26 GBG83206.1 - 8.4e-10 38.5 0.4 1.9e-09 37.3 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.15 GBG83206.1 - 0.0024 17.6 2.8 0.0051 16.5 2.8 1.5 1 0 0 1 1 1 1 Septum formation initiator YabA PF06156.13 GBG83206.1 - 0.021 15.4 2.0 0.043 14.4 2.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF4140 PF13600.6 GBG83206.1 - 0.027 14.9 1.6 0.027 14.9 1.6 1.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 GBG83206.1 - 0.04 12.8 2.6 0.065 12.1 2.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 GBG83206.1 - 0.044 14.1 1.9 0.071 13.4 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) bZIP_2 PF07716.15 GBG83206.1 - 0.045 13.8 2.1 0.045 13.8 2.1 3.1 2 1 1 3 3 3 0 Basic region leucine zipper TMF_DNA_bd PF12329.8 GBG83206.1 - 0.12 12.4 9.5 0.29 11.2 9.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 GBG83206.1 - 0.25 9.9 5.0 0.32 9.5 5.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TBCA PF02970.16 GBG83206.1 - 0.28 11.5 6.4 0.27 11.6 4.4 1.8 2 0 0 2 2 2 0 Tubulin binding cofactor A APG6_N PF17675.1 GBG83206.1 - 0.35 11.4 11.6 0.33 11.5 10.4 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 GBG83206.1 - 0.35 11.3 9.3 0.066 13.6 5.4 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NRBF2 PF08961.10 GBG83206.1 - 0.67 9.5 5.4 1.3 8.6 4.7 1.8 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF4515 PF14988.6 GBG83206.1 - 0.68 9.7 9.9 0.72 9.7 9.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) Exonuc_VII_L PF02601.15 GBG83206.1 - 0.7 9.4 4.0 1.1 8.8 4.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ZapB PF06005.12 GBG83206.1 - 0.95 9.9 15.3 0.25 11.8 10.0 2.6 2 1 0 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 GBG83206.1 - 3.8 7.8 7.6 2.9 8.2 5.5 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HALZ PF02183.18 GBG83206.1 - 4.4 7.6 7.5 6.4 7.1 1.7 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper PRKG1_interact PF15898.5 GBG83206.1 - 5.7 7.9 10.9 1.1 10.3 2.9 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TruD PF01142.18 GBG83207.1 - 2.7e-56 191.2 0.0 3.2e-31 108.6 0.0 5.1 4 1 1 5 5 5 5 tRNA pseudouridine synthase D (TruD) DUF4746 PF15928.5 GBG83207.1 - 0.29 10.5 5.8 1.2 8.5 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RVT_1 PF00078.27 GBG83208.1 - 1.4e-30 106.4 0.0 1.9e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG83208.1 - 0.072 13.1 0.0 7.6 6.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L34 Ribosomal_L29 PF00831.23 GBG83209.1 - 0.21 11.6 4.6 4.5 7.3 2.4 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein MCU PF04678.13 GBG83209.1 - 2.2 8.3 6.1 5 7.2 0.8 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF4187 PF13821.6 GBG83211.1 - 0.0015 18.3 1.3 0.0042 16.8 1.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG83211.1 - 0.0033 17.7 3.4 0.0047 17.2 0.3 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG83212.1 - 3.5e-07 30.0 2.7 5.9e-07 29.3 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG83212.1 - 0.028 14.1 2.2 0.076 12.8 2.1 1.8 2 0 0 2 2 2 0 Zinc knuckle DUF5082 PF16888.5 GBG83212.1 - 2 8.7 23.4 0.045 14.0 7.1 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 GBG83212.1 - 5.3 6.3 28.6 0.015 14.6 5.7 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) UMPH-1 PF05822.12 GBG83215.1 - 3.4e-82 275.7 0.5 7.3e-59 199.3 0.0 2.2 2 0 0 2 2 2 2 Pyrimidine 5'-nucleotidase (UMPH-1) RVT_1 PF00078.27 GBG83215.1 - 1.4e-25 90.2 0.0 2.3e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RdRP PF05183.12 GBG83216.1 - 1.3e-159 532.6 0.0 2.3e-94 317.1 0.0 3.6 2 1 0 2 2 2 2 RNA dependent RNA polymerase Mo-co_dimer PF03404.16 GBG83216.1 - 0.088 12.8 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain RHH_1 PF01402.21 GBG83216.1 - 0.099 12.6 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family DUF659 PF04937.15 GBG83217.1 - 1.4e-33 115.9 0.3 2.3e-33 115.2 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG83217.1 - 0.0005 19.8 0.5 0.0012 18.6 0.5 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TFIIA PF03153.13 GBG83217.1 - 0.041 13.9 33.4 0.063 13.3 33.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 GBG83217.1 - 1.3 9.0 3.6 2.8 8.0 3.6 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PGM_PMM_I PF02878.16 GBG83218.1 - 1.9e-16 60.0 0.0 3e-07 30.2 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 GBG83218.1 - 7.6e-12 45.2 0.8 4.2e-11 42.9 0.2 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 GBG83218.1 - 0.00024 21.3 0.5 0.00078 19.6 0.5 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DNA_pol_phi PF04931.13 GBG83218.1 - 0.013 13.7 9.4 0.018 13.2 9.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 GBG83218.1 - 0.29 10.3 1.2 0.52 9.5 1.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pyrid_oxidase_2 PF13883.6 GBG83219.1 - 5.5e-49 166.4 0.0 6.5e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 GBG83219.1 - 0.0025 18.0 0.0 0.0053 16.9 0.0 1.6 1 1 1 2 2 2 1 Pyridoxamine 5'-phosphate oxidase WD40 PF00400.32 GBG83220.1 - 5.5e-62 204.2 12.5 7.3e-10 39.3 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG83220.1 - 7.9e-25 87.0 0.1 0.00028 21.1 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG83220.1 - 1.2e-13 50.5 4.8 0.012 14.3 0.0 5.1 2 2 2 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 GBG83220.1 - 2.3e-12 47.2 0.0 8.3e-07 29.1 0.0 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GBG83220.1 - 7.1e-07 28.5 0.8 2.5 7.0 0.1 4.5 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GBG83220.1 - 1.9e-06 27.4 0.0 0.0015 17.9 0.0 3.4 1 1 2 4 4 4 1 WD40-like domain PALB2_WD40 PF16756.5 GBG83220.1 - 7.5e-06 25.1 0.1 0.014 14.3 0.0 3.4 1 1 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 GBG83220.1 - 0.001 17.5 0.0 0.0029 16.0 0.0 1.6 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 GBG83220.1 - 0.0015 17.6 0.0 0.058 12.4 0.0 2.7 1 1 2 3 3 3 2 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 GBG83220.1 - 0.0055 15.3 0.0 1.3 7.5 0.0 2.7 1 1 1 2 2 2 1 Cytochrome D1 heme domain IKI3 PF04762.12 GBG83220.1 - 0.027 12.5 0.0 0.049 11.6 0.0 1.4 1 0 0 1 1 1 0 IKI3 family SLT_beta PF02258.16 GBG83220.1 - 0.15 12.1 1.7 0.4 10.8 0.0 2.5 3 0 0 3 3 2 0 Shiga-like toxin beta subunit Dicty_CAR PF05462.11 GBG83221.1 - 3.2e-13 49.5 5.9 3.9e-13 49.2 5.9 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 GBG83221.1 - 5.7e-05 22.6 5.2 8.6e-05 22.0 5.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 GBG83221.1 - 0.0001 21.7 6.7 0.00012 21.4 6.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 GBG83221.1 - 0.0017 18.4 3.0 0.0021 18.1 0.2 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Frizzled PF01534.17 GBG83221.1 - 0.033 13.2 5.7 0.045 12.8 5.7 1.3 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region Spt20 PF12090.8 GBG83223.1 - 0.0035 17.0 7.9 0.0035 17.0 7.9 2.0 2 0 0 2 2 2 1 Spt20 family Connexin PF00029.19 GBG83223.1 - 1.6 8.5 7.5 0.1 12.3 0.8 2.1 2 0 0 2 2 2 0 Connexin Anoctamin PF04547.12 GBG83224.1 - 0.004 16.0 0.0 0.004 16.0 0.0 1.8 1 1 1 2 2 2 1 Calcium-activated chloride channel DUF2721 PF11026.8 GBG83224.1 - 0.0065 16.4 0.0 0.0065 16.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) DUF1304 PF06993.12 GBG83224.1 - 0.021 14.8 1.3 0.021 14.8 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1304) UCR_Fe-S_N PF10399.9 GBG83224.1 - 0.086 12.2 0.1 0.26 10.7 0.1 1.8 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF3270 PF11674.8 GBG83224.1 - 0.98 9.6 3.7 4 7.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) DUF898 PF05987.13 GBG83224.1 - 2.7 7.0 8.0 4.2 6.3 7.9 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DSBA PF01323.20 GBG83225.1 - 1.7e-25 89.9 0.0 2.5e-25 89.4 0.0 1.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 GBG83225.1 - 8.4e-07 29.3 0.0 0.00015 21.9 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 GBG83225.1 - 0.054 13.6 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain RVT_1 PF00078.27 GBG83228.1 - 3.1e-05 23.6 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plavaka PF18759.1 GBG83229.1 - 6.2e-11 42.1 0.1 9.6e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase MAP17 PF15807.5 GBG83229.1 - 2.7 8.2 6.9 5.9 7.1 6.9 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CDC45 PF02724.14 GBG83229.1 - 9.5 4.4 9.8 13 3.9 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein VEFS-Box PF09733.9 GBG83230.1 - 2.3e-45 153.8 3.6 2.3e-45 153.8 3.6 1.8 2 0 0 2 2 2 1 VEFS-Box of polycomb protein zf-Di19 PF05605.12 GBG83230.1 - 5.4 7.4 5.5 5.3 7.4 3.8 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NdhN PF11909.8 GBG83231.1 - 3.1e-32 111.4 0.0 5.7e-20 71.5 0.0 2.3 1 1 1 2 2 2 2 NADH-quinone oxidoreductase cyanobacterial subunit N CSN8_PSD8_EIF3K PF10075.9 GBG83232.1 - 4.3e-29 101.3 0.2 6e-29 100.9 0.2 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 GBG83232.1 - 1.4e-05 24.6 1.3 1.8e-05 24.3 1.3 1.1 1 0 0 1 1 1 1 SAC3/GANP family Asp_protease_2 PF13650.6 GBG83233.1 - 0.01 16.5 0.0 0.028 15.0 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF1192 PF06698.11 GBG83233.1 - 0.019 15.0 0.2 5.5 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Pkinase PF00069.25 GBG83234.1 - 6.2e-67 225.7 0.0 6.9e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83234.1 - 1.9e-45 155.2 0.0 2.1e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG83234.1 - 6.2e-06 25.7 0.0 3.8e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GBG83234.1 - 1.5e-05 24.0 0.0 2.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG83234.1 - 3.9e-05 23.7 0.1 5.2e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 GBG83234.1 - 0.00057 19.5 0.2 0.23 11.1 0.0 2.1 1 1 1 2 2 2 2 RIO1 family ABC1 PF03109.16 GBG83234.1 - 0.0031 17.7 0.0 0.0058 16.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Haspin_kinase PF12330.8 GBG83234.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GBG83234.1 - 0.067 12.5 0.5 0.17 11.2 0.4 1.6 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Plk4_PB2 PF18409.1 GBG83235.1 - 0.00017 22.2 0.0 0.017 15.8 0.0 3.0 1 1 0 1 1 1 1 Polo-like Kinase 4 Polo Box 2 Plk4_PB1 PF18190.1 GBG83235.1 - 0.00026 21.1 0.0 0.029 14.5 0.0 2.8 2 1 0 2 2 2 1 Polo-like Kinase 4 Polo Box 1 Attractin PF08037.11 GBG83235.1 - 3.4 7.8 6.1 0.62 10.1 0.1 3.0 3 0 0 3 3 3 0 Attractin family RVT_1 PF00078.27 GBG83237.1 - 2.3e-27 96.0 0.2 3.7e-26 92.0 0.1 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG83237.1 - 0.00024 21.3 11.0 0.0029 17.8 0.0 4.3 4 0 0 4 4 4 1 Retrotransposon gag protein Baculo_PEP_C PF04513.12 GBG83237.1 - 0.14 12.2 4.0 0.44 10.6 4.0 1.9 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 GBG83237.1 - 0.38 11.3 7.9 3 8.4 1.3 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sas10_Utp3 PF04000.15 GBG83237.1 - 2.2 9.0 5.2 25 5.6 0.0 3.9 4 0 0 4 4 4 0 Sas10/Utp3/C1D family CLZ PF16526.5 GBG83237.1 - 2.7 8.4 13.4 6.8 7.1 4.4 4.4 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snapin_Pallidin PF14712.6 GBG83237.1 - 2.7 8.5 10.8 0.62 10.5 3.4 3.1 3 0 0 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.12 GBG83237.1 - 3 7.9 9.1 7.7 6.6 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 GBG83237.1 - 4.6 7.1 5.8 10 6.0 1.4 2.9 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD BLOC1_2 PF10046.9 GBG83237.1 - 5.8 7.3 14.2 0.095 13.0 2.9 3.4 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 GBG83237.1 - 8.7 7.1 17.1 0.82 10.3 5.3 4.3 4 0 0 4 4 3 0 SlyX Syntaxin-6_N PF09177.11 GBG83237.1 - 9.6 6.8 10.7 73 4.0 6.1 4.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Mpp10 PF04006.12 GBG83239.1 - 6.3 5.1 25.1 7.7 4.8 25.1 1.1 1 0 0 1 1 1 0 Mpp10 protein Myb_DNA-bind_4 PF13837.6 GBG83240.1 - 0.014 15.8 0.0 0.079 13.3 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG83241.1 - 4.3e-06 26.6 2.2 9.6e-06 25.4 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle PPR PF01535.20 GBG83241.1 - 0.26 11.6 0.3 0.26 11.6 0.3 2.2 2 0 0 2 2 2 0 PPR repeat ECH_2 PF16113.5 GBG83241.1 - 0.38 10.2 3.8 0.54 9.7 3.8 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase zf-CCHC_2 PF13696.6 GBG83241.1 - 0.7 9.8 7.0 0.16 11.8 3.2 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF3818 PF12825.7 GBG83241.1 - 1.2 8.1 3.9 0.46 9.5 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) SWI-SNF_Ssr4 PF08549.10 GBG83241.1 - 8.2 4.9 15.3 10 4.6 15.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) FUSC PF04632.12 GBG83241.1 - 9 4.7 5.1 11 4.4 5.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family VWA_2 PF13519.6 GBG83242.1 - 5.1e-25 88.2 0.0 1.6e-24 86.6 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 GBG83242.1 - 9.6e-07 28.8 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like Phage_tube PF04985.14 GBG83242.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Phage tail tube protein FII UIM PF02809.20 GBG83242.1 - 0.022 14.7 4.9 0.022 14.7 4.9 4.1 4 0 0 4 4 4 0 Ubiquitin interaction motif IF-2 PF11987.8 GBG83244.1 - 2.6e-22 78.9 0.1 7.6e-22 77.4 0.0 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 GBG83244.1 - 8.3e-17 60.9 0.2 2.4e-16 59.4 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 GBG83244.1 - 6.2e-16 58.5 4.2 1.4e-10 41.4 0.1 2.6 2 0 0 2 2 2 2 Elongation factor Tu domain 2 DUF211 PF02680.14 GBG83244.1 - 0.087 13.0 3.8 0.35 11.0 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized ArCR, COG1888 Sugar_tr PF00083.24 GBG83246.1 - 1.5e-28 99.9 17.0 3.4e-18 65.8 4.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GBG83246.1 - 1.6e-21 76.6 24.8 3.9e-19 68.8 9.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Mpp10 PF04006.12 GBG83247.1 - 4.8 5.5 58.2 7.6 4.8 58.2 1.3 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG83247.1 - 7.7 4.6 60.1 8.5 4.4 60.1 1.0 1 0 0 1 1 1 0 Nop14-like family ABM PF03992.16 GBG83248.1 - 0.15 12.2 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase zf-CCHC PF00098.23 GBG83249.1 - 3e-06 27.0 3.8 5.8e-06 26.1 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG83249.1 - 0.023 14.7 1.7 0.11 12.5 0.7 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG83249.1 - 0.073 12.9 2.6 0.17 11.8 2.6 1.6 1 0 0 1 1 1 0 Zinc knuckle AP1AR PF15745.5 GBG83249.1 - 0.13 11.9 12.8 0.2 11.2 12.8 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein AAA_23 PF13476.6 GBG83249.1 - 0.16 12.4 8.7 0.29 11.6 8.7 1.4 1 0 0 1 1 1 0 AAA domain SmAKAP PF15127.6 GBG83249.1 - 1.1 10.6 10.4 3.6 8.8 10.3 2.1 1 1 0 1 1 1 0 Small membrane A-kinase anchor protein DUF1682 PF07946.14 GBG83249.1 - 2.4 7.3 21.1 3.9 6.6 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ATPase-cat_bd PF12156.8 GBG83250.1 - 0.0061 17.3 0.8 0.014 16.1 0.8 1.6 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase DUF89 PF01937.19 GBG83251.1 - 3.5e-47 161.1 0.0 4.1e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF5587 PF17825.1 GBG83251.1 - 0.14 9.4 0.0 0.17 9.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5587) Gln-synt_C PF00120.24 GBG83252.1 - 7.5e-17 61.3 0.0 8.8e-15 54.5 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG83252.1 - 6.4e-11 41.8 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Metallophos PF00149.28 GBG83253.1 - 2.6e-05 24.8 0.0 4.7e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GBG83253.1 - 0.00061 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CNDH2_M PF16869.5 GBG83258.1 - 0.14 12.9 1.8 0.26 12.0 1.4 1.6 1 1 0 1 1 1 0 PF16858 PAP2 PF01569.21 GBG83259.1 - 0.0085 15.9 0.2 0.011 15.5 0.2 1.1 1 0 0 1 1 1 1 PAP2 superfamily Jnk-SapK_ap_N PF09744.9 GBG83260.1 - 0.0036 17.5 3.3 0.0036 17.5 3.3 3.2 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 DUF4298 PF14131.6 GBG83260.1 - 0.057 13.4 0.1 2.1 8.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF3347 PF11827.8 GBG83260.1 - 0.31 11.2 1.9 0.74 10.0 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Pkinase_Tyr PF07714.17 GBG83261.1 - 6.9e-36 123.8 0.0 1.1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83261.1 - 1e-33 116.9 0.0 2.5e-33 115.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG83261.1 - 0.003 16.4 0.0 0.0045 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF3179 PF11376.8 GBG83261.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) CAP_N PF01213.19 GBG83261.1 - 1 8.8 9.6 0.24 10.8 5.6 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GBG83261.1 - 1.7 8.7 9.3 0.46 10.5 1.6 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase_Tyr PF07714.17 GBG83263.1 - 2.9e-37 128.4 0.0 4.8e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83263.1 - 8.8e-34 117.1 0.0 1.3e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG83263.1 - 0.016 15.2 0.0 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG83263.1 - 0.017 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Myb_DNA-bind_4 PF13837.6 GBG83264.1 - 1.3e-07 31.9 3.5 4.1e-07 30.3 0.1 3.3 4 0 0 4 4 4 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG83264.1 - 0.83 9.8 3.9 0.52 10.4 0.7 2.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG83265.1 - 5.2e-35 120.6 0.0 8.1e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PAT1 PF09770.9 GBG83265.1 - 0.044 12.1 29.5 0.064 11.5 29.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 GBG83265.1 - 1.6 7.4 18.8 3.2 6.4 18.8 1.6 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 GBG83265.1 - 3.3 7.6 38.9 0.17 11.9 30.6 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1612 PF07756.12 GBG83267.1 - 0.11 12.8 2.9 0.076 13.3 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) Pkinase_Tyr PF07714.17 GBG83268.1 - 1.4e-36 126.1 0.0 2.8e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83268.1 - 4.5e-33 114.7 0.0 8.1e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF659 PF04937.15 GBG83268.1 - 5.2e-25 88.1 1.0 8.9e-25 87.3 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SGL PF08450.12 GBG83268.1 - 0.0081 15.8 0.1 0.037 13.6 0.0 2.0 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Pkinase_fungal PF17667.1 GBG83268.1 - 0.04 12.7 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-CCHC_2 PF13696.6 GBG83271.1 - 0.43 10.4 4.4 0.18 11.7 1.7 1.7 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG83272.1 - 1.6e-26 92.2 0.3 2.9e-26 91.4 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83272.1 - 7.1e-24 84.1 0.7 1.4e-23 83.2 0.7 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83272.1 - 1.5e-11 44.3 0.2 7.2e-05 22.4 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_43 PF04616.14 GBG83273.1 - 1.8e-19 70.2 0.7 3.3e-19 69.3 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 5_nucleotid PF05761.14 GBG83274.1 - 3.6e-62 210.8 0.0 4.7e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase family 5_nucleotid PF05761.14 GBG83275.1 - 2.8e-64 217.7 0.0 3.5e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family GP41 PF00517.17 GBG83276.1 - 4.9 7.0 6.1 1.3 8.9 3.1 1.6 2 0 0 2 2 2 0 Retroviral envelope protein LMBR1 PF04791.16 GBG83276.1 - 5.6 5.8 9.0 15 4.4 9.0 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein Tudor_3 PF18115.1 GBG83277.1 - 2.9 7.8 4.5 15 5.5 0.3 2.5 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Ribosomal_L28e PF01778.17 GBG83279.1 - 3.2e-28 98.8 1.7 4.5e-28 98.3 1.7 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Lipase_3 PF01764.25 GBG83280.1 - 3.7e-18 65.7 0.0 7.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) RT_RNaseH_2 PF17919.1 GBG83281.1 - 3.3e-26 91.2 0.0 1.1e-25 89.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83281.1 - 1e-25 90.6 0.0 1.6e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83281.1 - 3.1e-24 85.3 0.0 9.2e-24 83.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83281.1 - 2.7e-18 65.8 0.7 2.5e-17 62.7 0.3 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG83281.1 - 4.3e-08 33.4 0.0 1.2e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG83281.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG83281.1 - 0.028 14.7 0.0 0.28 11.5 0.0 2.8 2 0 0 2 2 1 0 Retrotransposon gag protein LRRFIP PF09738.9 GBG83281.1 - 0.034 13.6 4.4 0.078 12.4 4.4 1.5 1 0 0 1 1 1 0 LRRFIP family Chromo PF00385.24 GBG83281.1 - 0.04 13.8 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG83281.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Lys-AminoMut_A PF09043.11 GBG83281.1 - 0.37 9.2 0.6 0.64 8.4 0.6 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Snapin_Pallidin PF14712.6 GBG83281.1 - 0.76 10.2 0.0 0.76 10.2 0.0 3.6 4 0 0 4 4 3 0 Snapin/Pallidin Pkinase PF00069.25 GBG83286.1 - 1.4e-36 126.2 0.0 2.1e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83286.1 - 1.2e-33 116.5 0.0 2.3e-33 115.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.6 GBG83286.1 - 2.5e-06 27.4 0.1 4.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Pkinase_fungal PF17667.1 GBG83286.1 - 0.0044 15.8 0.0 0.0086 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase SGL PF08450.12 GBG83286.1 - 0.007 16.0 0.0 0.14 11.7 0.0 2.7 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region DAG1 PF05454.11 GBG83286.1 - 0.013 14.9 1.3 0.032 13.6 0.0 2.1 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) APH PF01636.23 GBG83286.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1180 PF06679.12 GBG83286.1 - 0.098 13.1 6.5 0.27 11.6 6.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Apt1 PF10351.9 GBG83286.1 - 0.16 10.8 2.3 0.23 10.3 2.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 GBG83286.1 - 1.5 7.9 14.8 2.5 7.2 14.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 GBG83286.1 - 1.8 7.2 6.5 2.5 6.7 6.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 GBG83286.1 - 2.5 7.9 12.5 4.1 7.2 12.5 1.3 1 0 0 1 1 1 0 SPX domain CENP-F_leu_zip PF10473.9 GBG83291.1 - 1.3 9.0 13.4 0.19 11.7 0.3 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nucleo_P87 PF07267.11 GBG83292.1 - 2.1 7.1 11.0 3.9 6.2 11.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf_Rg PF17915.1 GBG83293.1 - 0.087 12.2 0.0 0.26 10.7 0.0 1.8 1 0 0 1 1 1 0 Reverse gyrase zinc finger Integrase_H2C2 PF17921.1 GBG83294.1 - 9.3e-20 70.5 0.4 2e-19 69.4 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG83294.1 - 3.8e-08 33.2 0.0 7.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG83294.1 - 2.4e-06 27.2 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83294.1 - 3.2e-06 27.7 0.0 7.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83294.1 - 8.2e-05 23.1 0.0 0.00027 21.4 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG83294.1 - 0.00064 19.9 0.1 0.0019 18.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG83294.1 - 0.0048 16.7 0.0 0.099 12.4 0.0 2.5 2 1 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG83294.1 - 0.0079 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RasGEF_N PF00618.20 GBG83294.1 - 0.11 12.8 0.0 0.99 9.7 0.0 2.2 2 0 0 2 2 2 0 RasGEF N-terminal motif NB-ARC PF00931.22 GBG83295.1 - 1.2e-38 132.7 0.0 1.7e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain LRR_8 PF13855.6 GBG83295.1 - 2.4e-14 52.8 33.4 0.0002 21.1 1.3 8.0 6 3 1 8 8 8 4 Leucine rich repeat LRR_4 PF12799.7 GBG83295.1 - 1.7e-09 37.8 36.8 0.13 12.8 0.4 9.8 4 2 10 14 14 13 7 Leucine Rich repeats (2 copies) NACHT PF05729.12 GBG83295.1 - 7.7e-07 29.2 0.0 2.4e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GBG83295.1 - 9.2e-06 26.1 0.0 3.6e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG83295.1 - 0.0028 17.9 0.1 0.019 15.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 GBG83295.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsmF_methylt_CI PF17126.5 GBG83295.1 - 0.023 14.8 0.0 7.4 6.7 0.0 3.6 4 0 0 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain Sigma54_activat PF00158.26 GBG83295.1 - 0.083 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 GBG83295.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 GBG83295.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Histone PF00125.24 GBG83299.1 - 1.6e-24 86.8 0.4 3.4e-24 85.7 0.4 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SDA1 PF05285.12 GBG83299.1 - 4.8 6.5 5.8 7.4 5.9 5.8 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG83300.1 - 0.022 13.6 4.6 0.034 13.0 4.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Drc1-Sld2 PF11719.8 GBG83300.1 - 0.024 14.2 15.9 0.24 10.9 1.0 2.0 2 0 0 2 2 2 0 DNA replication and checkpoint protein Nop14 PF04147.12 GBG83300.1 - 0.99 7.5 42.6 0.33 9.1 21.3 2.1 2 0 0 2 2 2 0 Nop14-like family SpoIIIAH PF12685.7 GBG83300.1 - 1.5 8.6 14.7 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein CPSF100_C PF13299.6 GBG83300.1 - 5.5 7.1 19.7 1.8 8.7 7.0 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal NB-ARC PF00931.22 GBG83302.1 - 1.3e-32 113.0 0.0 1.9e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain LRR_8 PF13855.6 GBG83302.1 - 8.9e-15 54.2 37.9 0.00041 20.1 3.5 7.9 5 2 3 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 GBG83302.1 - 3.1e-06 27.4 50.0 0.035 14.6 2.4 9.5 4 3 6 12 12 12 7 Leucine Rich repeats (2 copies) NACHT PF05729.12 GBG83302.1 - 0.00021 21.3 0.0 0.00073 19.5 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GBG83302.1 - 0.00078 19.7 0.0 0.0026 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG83302.1 - 0.0011 19.3 0.2 0.0047 17.3 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 GBG83302.1 - 0.017 15.7 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GBG83302.1 - 0.028 14.9 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 GBG83302.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GBG83302.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GBG83302.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 GBG83302.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RT_RNaseH_2 PF17919.1 GBG83304.1 - 7.3e-30 103.0 0.0 6e-16 58.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83304.1 - 2.5e-28 98.5 0.0 5e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83304.1 - 4.1e-15 55.9 0.1 1e-10 41.5 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83304.1 - 4.6e-13 49.0 0.0 2.9e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG83304.1 - 2.5e-12 47.0 0.1 9.6e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG83304.1 - 0.00047 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger NB-ARC PF00931.22 GBG83306.1 - 3e-39 134.7 0.0 4.6e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain LRR_8 PF13855.6 GBG83306.1 - 2.1e-14 53.0 33.0 7.9e-05 22.3 4.5 6.8 4 3 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 GBG83306.1 - 3.1e-08 33.8 33.0 0.012 16.0 1.5 9.1 5 3 3 8 8 8 4 Leucine Rich repeats (2 copies) NACHT PF05729.12 GBG83306.1 - 9.2e-07 28.9 0.0 2.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GBG83306.1 - 4.1e-05 24.0 0.0 0.00018 21.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG83306.1 - 0.0024 18.2 0.0 0.0067 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GBG83306.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG83306.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GBG83306.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GBG83306.1 - 0.067 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GBG83306.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RVT_1 PF00078.27 GBG83308.1 - 9.5e-09 35.1 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UpxZ PF06603.11 GBG83308.1 - 0.14 12.5 0.0 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists RT_RNaseH PF17917.1 GBG83309.1 - 2.5e-22 79.1 0.0 5.2e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83309.1 - 2.5e-20 72.4 0.0 4.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83309.1 - 2.4e-14 53.1 0.6 6.6e-14 51.8 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83309.1 - 0.053 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Topo_Zn_Ribbon PF08272.11 GBG83309.1 - 0.078 12.7 1.5 0.099 12.3 0.3 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like RVP_2 PF08284.11 GBG83309.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83309.1 - 0.17 11.7 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 GBG83310.1 - 8.6e-09 35.6 0.0 2.4e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG83310.1 - 0.0047 16.6 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) Chromo PF00385.24 GBG83310.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TraD PF06412.11 GBG83310.1 - 0.24 11.2 3.7 2.2 8.1 0.0 3.0 4 0 0 4 4 4 0 Conjugal transfer protein TraD RVT_1 PF00078.27 GBG83314.1 - 1.5e-28 99.8 0.0 2.4e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG83314.1 - 0.045 13.7 0.1 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L34 NB-ARC PF00931.22 GBG83315.1 - 3.4e-38 131.3 0.0 4.8e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain LRR_8 PF13855.6 GBG83315.1 - 1.7e-16 59.7 36.0 1.2e-06 28.2 0.6 7.7 5 2 2 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 GBG83315.1 - 3.1e-11 43.3 32.6 0.029 14.8 0.4 9.1 6 2 6 12 12 12 5 Leucine Rich repeats (2 copies) AAA_16 PF13191.6 GBG83315.1 - 3.5e-06 27.5 0.1 2e-05 25.1 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GBG83315.1 - 1.4e-05 25.0 0.0 8e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 GBG83315.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4594 PF15266.6 GBG83316.1 - 0.029 14.7 0.6 0.16 12.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4594) RT_RNaseH_2 PF17919.1 GBG83317.1 - 4.2e-24 84.5 0.0 1.3e-23 82.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83317.1 - 7e-24 84.1 0.7 5.7e-23 81.2 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83317.1 - 8.8e-15 54.6 0.4 1.8e-14 53.6 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83317.1 - 1.1e-08 35.2 0.0 5.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG83317.1 - 0.0017 18.6 1.4 0.0074 16.5 0.2 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG83317.1 - 0.022 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger SpvB PF03534.13 GBG83317.1 - 0.054 12.7 0.4 3.2 6.9 1.5 2.3 2 0 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein RT_RNaseH_2 PF17919.1 GBG83318.1 - 2.6e-27 94.8 0.0 4.8e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83318.1 - 8.4e-25 87.1 0.0 1.4e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83318.1 - 1.7e-12 47.4 0.3 2.9e-12 46.6 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG83318.1 - 0.036 13.9 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) SDA1 PF05285.12 GBG83318.1 - 0.74 9.2 18.3 1.1 8.7 18.3 1.1 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG83318.1 - 0.87 9.8 10.9 1.4 9.2 10.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Lin-8 PF03353.15 GBG83318.1 - 1.2 8.7 5.8 1.7 8.1 5.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 GBG83318.1 - 1.6 8.0 16.6 2.1 7.6 16.6 1.1 1 0 0 1 1 1 0 BUD22 BAMBI PF06211.12 GBG83320.1 - 0.019 15.2 0.1 0.044 14.0 0.1 1.6 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain DUF659 PF04937.15 GBG83321.1 - 1.4e-14 54.2 0.0 2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CENP-F_leu_zip PF10473.9 GBG83322.1 - 0.0034 17.4 9.7 0.0076 16.3 5.3 2.1 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BST2 PF16716.5 GBG83322.1 - 0.0042 17.6 3.5 0.0042 17.6 3.5 2.2 2 0 0 2 2 2 1 Bone marrow stromal antigen 2 DUF4712 PF15830.5 GBG83322.1 - 0.017 14.8 0.9 0.017 14.8 0.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4712) NanE PF04131.14 GBG83322.1 - 0.13 11.5 0.2 0.59 9.3 0.1 1.8 1 1 1 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TATR PF03430.13 GBG83322.1 - 0.16 10.4 0.5 0.18 10.2 0.5 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PspB PF06667.12 GBG83322.1 - 0.23 11.5 3.7 2.8 8.0 0.5 2.6 2 1 0 2 2 2 0 Phage shock protein B TerB_C PF15615.6 GBG83322.1 - 0.3 11.4 8.5 0.069 13.5 4.6 1.9 1 1 1 2 2 2 0 TerB-C domain GrpE PF01025.19 GBG83322.1 - 0.58 9.8 8.4 0.35 10.5 4.3 2.0 2 0 0 2 2 2 0 GrpE DivIC PF04977.15 GBG83322.1 - 0.75 9.6 10.0 1.1 9.0 3.6 2.4 2 0 0 2 2 2 0 Septum formation initiator XhlA PF10779.9 GBG83322.1 - 0.88 9.8 7.4 8 6.7 1.8 2.5 2 1 0 2 2 2 0 Haemolysin XhlA Csm1_N PF18504.1 GBG83322.1 - 2.5 8.5 12.7 0.82 10.1 3.6 2.7 3 0 0 3 3 3 0 Csm1 N-terminal domain RVT_1 PF00078.27 GBG83323.1 - 3.1e-20 72.6 0.0 5.7e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG83324.1 - 4.4e-07 29.7 4.1 7.4e-07 29.0 4.1 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF4820 PF16091.5 GBG83324.1 - 0.044 13.1 0.0 0.044 13.1 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4820) zf-CCHC_4 PF14392.6 GBG83324.1 - 0.48 10.2 1.7 0.86 9.4 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG83325.1 - 2.7e-11 43.4 0.1 7.8e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83325.1 - 4.6e-08 32.9 0.0 1.2e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83325.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain PknG_TPR PF16918.5 GBG83327.1 - 0.034 12.9 0.0 0.064 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat RTA1 PF04479.13 GBG83328.1 - 0.98 9.0 7.9 5.8 6.5 0.0 4.7 4 2 3 7 7 7 0 RTA1 like protein DUF4360 PF14273.6 GBG83331.1 - 5.2e-33 114.4 0.0 5.9e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) zf-CCHC PF00098.23 GBG83332.1 - 6.9e-06 25.9 4.0 1.4e-05 24.9 4.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG83332.1 - 0.015 15.1 3.8 0.033 14.0 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle UPF0270 PF06794.12 GBG83332.1 - 0.2 11.8 1.2 1.6 8.8 0.4 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Phosducin PF02114.16 GBG83332.1 - 5.1 5.9 11.0 2.2 7.2 8.0 1.9 1 1 0 1 1 1 0 Phosducin ALMT PF11744.8 GBG83332.1 - 6.4 5.5 9.9 9.1 5.0 9.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RVT_1 PF00078.27 GBG83333.1 - 3.2e-29 102.0 0.1 5.2e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.24 GBG83333.1 - 2e-18 67.0 2.0 2e-18 67.0 2.0 3.2 3 1 1 4 4 4 1 Core histone H2A/H2B/H3/H4 RT_RNaseH_2 PF17919.1 GBG83333.1 - 0.00016 21.6 0.0 0.00044 20.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CENP-T_C PF15511.6 GBG83333.1 - 0.00026 21.1 0.1 0.00065 19.8 0.1 1.7 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Peptidase_S49_N PF08496.10 GBG83334.1 - 1.9 8.5 6.8 3.4 7.7 6.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ferlin_C PF16165.5 GBG83334.1 - 3.2 7.7 6.0 8.2 6.3 6.0 1.6 1 0 0 1 1 1 0 Ferlin C-terminus Casc1_N PF15927.5 GBG83334.1 - 4.9 6.8 14.3 8 6.1 14.3 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DDE_Tnp_4 PF13359.6 GBG83337.1 - 9.3e-07 28.6 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease TFA2_Winged_2 PF18121.1 GBG83337.1 - 0.045 13.4 1.3 1.8 8.3 0.1 3.2 2 1 1 3 3 3 0 TFA2 Winged helix domain 2 YmaF PF12788.7 GBG83337.1 - 0.064 13.8 0.3 0.14 12.7 0.3 1.5 1 0 0 1 1 1 0 YmaF family DUF2332 PF10094.9 GBG83346.1 - 0.17 11.3 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) Antimicrobial19 PF08225.11 GBG83348.1 - 0.82 9.3 3.6 76 3.1 0.0 3.2 3 0 0 3 3 3 0 Pseudin antimicrobial peptide Antimicrobial19 PF08225.11 GBG83349.1 - 0.82 9.3 3.6 76 3.1 0.0 3.2 3 0 0 3 3 3 0 Pseudin antimicrobial peptide RT_RNaseH PF17917.1 GBG83352.1 - 9.6e-23 80.5 0.0 2e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83352.1 - 4.2e-21 74.9 0.0 9.4e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG83352.1 - 1.2e-06 28.9 0.0 3.9e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83352.1 - 0.0031 18.1 0.0 0.011 16.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG83352.1 - 0.0068 16.2 0.8 0.012 15.4 0.8 1.3 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG83352.1 - 0.039 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain Glyco_hydro_17 PF00332.18 GBG83353.1 - 1.5e-71 241.6 0.0 1.8e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Pkinase PF00069.25 GBG83357.1 - 2.5e-48 164.8 0.0 6.4e-23 81.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83357.1 - 2.9e-47 161.1 0.0 2e-23 83.0 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase WD40 PF00400.32 GBG83357.1 - 3.2e-15 56.3 1.4 4.4e-05 24.2 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat PIP49_C PF12260.8 GBG83357.1 - 2.4e-05 24.1 0.1 0.21 11.2 0.1 2.8 2 1 0 2 2 2 2 Protein-kinase domain of FAM69 Nup160 PF11715.8 GBG83357.1 - 0.0055 15.4 0.1 10 4.6 0.0 4.2 3 1 2 5 5 5 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GBG83357.1 - 0.0094 16.2 0.3 1.8 8.9 0.2 3.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Adenylate_cycl PF01295.18 GBG83357.1 - 0.48 9.0 4.8 3 6.4 0.5 2.2 2 0 0 2 2 2 0 Adenylate cyclase, class-I Phage_Mu_Gam PF07352.12 GBG83357.1 - 0.64 9.9 18.3 1.5 8.7 4.6 2.7 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Fib_alpha PF08702.10 GBG83357.1 - 2.3 8.4 24.7 3.6 7.8 8.5 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MotA_ExbB PF01618.16 GBG83357.1 - 5.8 6.7 8.4 16 5.3 1.1 2.6 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family FAM184 PF15665.5 GBG83357.1 - 6.6 6.5 39.5 7.8 6.2 15.6 2.3 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B MULE PF10551.9 GBG83359.1 - 1.1e-16 61.0 0.0 1.9e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG83359.1 - 1e-10 41.5 0.0 3.3e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.18 GBG83359.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family RT_RNaseH_2 PF17919.1 GBG83360.1 - 1.6e-24 85.8 0.0 3.8e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83360.1 - 5.5e-23 81.3 0.0 1.3e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83360.1 - 2.5e-20 72.3 0.1 5e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG83360.1 - 3.5e-11 43.1 1.7 4.2e-10 39.5 0.0 3.0 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG83360.1 - 9.6e-08 31.9 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83360.1 - 7.2e-07 29.8 0.0 1.8e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG83360.1 - 1.8e-06 28.1 0.0 5.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG83360.1 - 6.5e-05 23.4 0.0 0.00015 22.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG83360.1 - 0.027 14.7 0.0 0.072 13.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG83360.1 - 0.05 13.9 0.2 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG83360.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease MRI PF15325.6 GBG83360.1 - 2.4 9.3 4.5 1.8 9.7 0.2 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection Pkinase PF00069.25 GBG83361.1 - 1.2e-13 51.1 0.0 1.8e-12 47.2 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83361.1 - 5.2e-12 45.6 0.1 1.6e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.32 GBG83361.1 - 2.9e-07 31.1 0.5 0.33 11.9 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Rab5-bind PF09311.11 GBG83361.1 - 2.5e-05 23.8 25.2 2.5e-05 23.8 25.2 4.6 5 0 0 5 5 5 1 Rabaptin-like protein Nuc_N PF14448.6 GBG83361.1 - 0.076 12.9 0.7 3.1 7.7 0.1 2.6 2 0 0 2 2 2 0 Nuclease N terminal Lip_prot_lig_C PF10437.9 GBG83361.1 - 0.11 12.5 6.5 11 6.1 0.1 4.8 2 2 3 5 5 5 0 Bacterial lipoate protein ligase C-terminus DUF1664 PF07889.12 GBG83361.1 - 0.16 12.0 20.8 0.57 10.2 1.1 4.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GBG83361.1 - 7.5 6.6 5.4 3.2 7.8 0.5 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RT_RNaseH PF17917.1 GBG83362.1 - 3e-30 104.6 0.0 5.5e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83362.1 - 9.3e-30 102.6 0.0 1.6e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83362.1 - 1.4e-15 57.1 0.7 1.1e-14 54.2 0.0 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG83362.1 - 6e-12 45.3 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG83362.1 - 1.9e-11 44.2 0.0 1.3e-10 41.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG83362.1 - 3.3e-05 24.0 0.0 8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Pkinase_Tyr PF07714.17 GBG83363.1 - 8.7e-25 87.5 0.0 1.8e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83363.1 - 7.6e-24 84.5 0.0 1.8e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG83363.1 - 9.5e-10 38.9 0.1 0.0046 17.8 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat CENP-F_leu_zip PF10473.9 GBG83363.1 - 0.0071 16.4 14.0 0.0071 16.4 14.0 4.4 1 1 4 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ANAPC4_WD40 PF12894.7 GBG83363.1 - 0.02 15.2 0.1 1.8 8.9 0.0 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG83363.1 - 0.029 13.0 3.5 5.5 5.5 0.3 3.4 2 1 2 4 4 4 0 Nucleoporin Nup120/160 HMMR_N PF15905.5 GBG83363.1 - 0.044 13.3 37.6 0.3 10.5 25.8 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Rab5-bind PF09311.11 GBG83363.1 - 0.2 11.0 31.3 0.37 10.2 31.3 1.3 1 0 0 1 1 1 0 Rabaptin-like protein GAS PF13851.6 GBG83363.1 - 0.25 10.7 37.4 0.15 11.3 12.3 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 GBG83363.1 - 0.62 10.1 36.2 0.12 12.4 14.8 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Lip_prot_lig_C PF10437.9 GBG83363.1 - 0.82 9.7 6.3 10 6.2 0.1 4.0 2 2 2 4 4 4 0 Bacterial lipoate protein ligase C-terminus ApoO PF09769.9 GBG83363.1 - 1.1 9.2 4.5 3.7 7.5 0.4 2.5 2 0 0 2 2 2 0 Apolipoprotein O CCDC144C PF14915.6 GBG83363.1 - 1.4 8.0 35.0 8.3 5.4 34.4 2.1 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region Jnk-SapK_ap_N PF09744.9 GBG83363.1 - 6.8 6.9 40.5 3.9 7.7 17.2 2.8 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Pkinase_Tyr PF07714.17 GBG83364.1 - 1.4e-24 86.8 0.0 2.6e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83364.1 - 2e-22 79.8 0.0 3.8e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG83364.1 - 8.7e-07 29.6 3.7 0.0029 18.4 0.1 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG83364.1 - 0.051 13.9 0.7 0.52 10.6 0.3 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain IFT57 PF10498.9 GBG83364.1 - 0.55 9.1 16.3 1.4 7.8 2.4 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 GBG83364.1 - 1.7 8.7 6.9 0.36 10.9 0.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CtIP_N PF10482.9 GBG83364.1 - 3.9 7.6 27.1 0.65 10.1 1.0 4.4 2 1 2 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain Atg14 PF10186.9 GBG83364.1 - 4.8 6.2 15.1 3.6 6.6 5.6 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 GBG83364.1 - 5 7.6 15.4 13 6.2 0.2 5.4 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF4472 PF14739.6 GBG83364.1 - 9.8 7.0 27.1 1.8 9.4 6.6 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4472) Pkinase_Tyr PF07714.17 GBG83365.1 - 5.4e-23 81.6 0.0 7.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83365.1 - 7.9e-21 74.6 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG83365.1 - 2.1e-09 37.8 0.0 9.3e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat CENP-F_leu_zip PF10473.9 GBG83365.1 - 0.0012 18.9 3.9 0.32 11.0 0.1 2.9 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 GBG83365.1 - 0.21 10.9 5.2 0.34 10.2 5.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mito_fiss_reg PF05308.11 GBG83367.1 - 0.035 14.2 14.1 0.059 13.5 14.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator TraC PF07820.12 GBG83367.1 - 2.7 8.4 12.0 0.37 11.2 0.9 3.7 3 1 0 3 3 3 0 TraC-like protein MCU PF04678.13 GBG83367.1 - 8.6 6.4 13.7 5.5 7.0 0.4 2.9 2 1 0 2 2 2 0 Mitochondrial calcium uniporter Pkinase PF00069.25 GBG83369.1 - 7.4e-25 87.8 0.0 1.5e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83369.1 - 5.2e-24 84.9 0.0 8.7e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG83369.1 - 6.3e-07 30.0 0.0 0.047 14.6 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat UPF0242 PF06785.11 GBG83369.1 - 6.5e-06 26.4 2.7 9.7e-06 25.8 2.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FAM184 PF15665.5 GBG83369.1 - 0.01 15.6 12.7 0.016 15.0 12.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B ANAPC4_WD40 PF12894.7 GBG83369.1 - 0.072 13.4 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain AKNA PF12443.8 GBG83369.1 - 0.11 13.2 0.5 0.34 11.6 0.3 1.9 1 1 0 1 1 1 0 AT-hook-containing transcription factor Nup160 PF11715.8 GBG83369.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CENP-F_leu_zip PF10473.9 GBG83369.1 - 0.18 11.9 18.0 0.34 10.9 13.0 2.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 GBG83369.1 - 0.26 10.1 9.0 0.42 9.5 9.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein JIP_LZII PF16471.5 GBG83369.1 - 0.43 10.8 14.2 0.027 14.7 5.4 2.5 1 1 0 2 2 2 0 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 GBG83369.1 - 0.53 10.4 11.5 0.42 10.7 6.7 2.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein FapA PF03961.13 GBG83369.1 - 0.67 8.5 4.1 0.97 8.0 4.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 GBG83369.1 - 0.94 8.5 4.8 1.7 7.7 4.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 GBG83369.1 - 1.1 8.6 11.6 2.6 7.4 11.6 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding BBP1_C PF15272.6 GBG83369.1 - 1.5 8.6 9.7 0.19 11.5 2.0 2.1 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF4140 PF13600.6 GBG83369.1 - 2.2 8.8 8.3 2.7 8.5 1.3 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 GBG83369.1 - 2.9 8.2 9.6 7.6 6.8 1.5 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 bZIP_Maf PF03131.17 GBG83369.1 - 3 8.4 9.7 2.2 8.9 2.1 2.5 1 1 2 3 3 3 0 bZIP Maf transcription factor Nup54 PF13874.6 GBG83369.1 - 4.5 7.4 9.2 4 7.5 2.2 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Seryl_tRNA_N PF02403.22 GBG83369.1 - 5.4 7.3 8.5 22 5.3 7.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cnn_1N PF07989.11 GBG83369.1 - 6.8 6.9 13.1 13 6.0 7.4 2.7 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF4200 PF13863.6 GBG83369.1 - 9.4 6.7 13.4 17 5.9 13.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) XhlA PF10779.9 GBG83369.1 - 9.8 6.5 6.9 3.9 7.8 1.7 2.4 2 0 0 2 2 2 0 Haemolysin XhlA DUF3043 PF11241.8 GBG83370.1 - 0.5 10.4 2.6 19 5.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DDE_Tnp_4 PF13359.6 GBG83371.1 - 6.1e-16 58.5 0.0 9.8e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83371.1 - 5e-07 29.5 0.0 8.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG83372.1 - 3.7e-08 33.6 0.6 1e-07 32.2 0.3 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG83372.1 - 0.00031 20.8 0.8 0.00082 19.4 0.8 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG83373.1 - 4.4e-10 39.8 5.3 7.8e-10 39.0 5.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG83373.1 - 0.075 13.2 0.5 0.17 12.1 0.5 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG83374.1 - 1.2e-26 92.7 0.0 2.1e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83374.1 - 3.2e-23 82.0 0.0 6.1e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83374.1 - 3.5e-14 52.9 0.1 5.2e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG83374.1 - 4.1 5.6 9.3 5.8 5.1 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG83376.1 - 3.2e-30 105.0 0.0 1.2e-29 103.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG83376.1 - 1.7e-07 30.9 0.1 4.2e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CDC45 PF02724.14 GBG83376.1 - 0.11 10.8 24.4 0.14 10.4 24.4 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG83376.1 - 0.36 10.9 24.7 0.64 10.1 24.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GBG83376.1 - 1.7 6.8 19.8 2.3 6.3 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG83376.1 - 2 6.4 23.3 2.9 5.9 23.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 GBG83376.1 - 2.4 7.5 18.0 5.2 6.4 18.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Merozoite_SPAM PF07133.11 GBG83376.1 - 3.5 7.6 23.6 6.5 6.7 23.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Pkinase_Tyr PF07714.17 GBG83377.1 - 1.2e-24 87.1 0.0 2.3e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83377.1 - 1.9e-20 73.4 0.0 3.7e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Myb_DNA-bind_4 PF13837.6 GBG83377.1 - 3.3e-08 33.8 0.2 3.3e-08 33.8 0.2 3.7 4 0 0 4 4 3 1 Myb/SANT-like DNA-binding domain WD40 PF00400.32 GBG83377.1 - 4.8e-08 33.5 0.0 0.00067 20.4 0.0 4.3 3 0 0 3 3 3 1 WD domain, G-beta repeat APG6_N PF17675.1 GBG83377.1 - 0.00067 20.2 22.0 0.00067 20.2 22.0 4.7 2 1 2 4 4 4 2 Apg6 coiled-coil region Spc7 PF08317.11 GBG83377.1 - 0.0021 17.0 18.7 0.0021 17.0 18.7 3.7 2 1 2 4 4 4 2 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 GBG83377.1 - 0.0035 17.4 10.9 0.0037 17.3 1.9 3.2 4 0 0 4 4 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 GBG83377.1 - 0.0045 17.5 31.4 0.0045 17.5 31.4 3.5 2 1 2 4 4 4 1 Fez1 DUF2730 PF10805.8 GBG83377.1 - 0.01 15.9 19.4 0.022 14.9 4.4 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF2730) DUF3584 PF12128.8 GBG83377.1 - 0.012 13.2 33.6 0.016 12.8 32.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ANAPC4_WD40 PF12894.7 GBG83377.1 - 0.019 15.3 0.0 1.7 9.0 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain MT PF12777.7 GBG83377.1 - 0.025 13.6 1.9 0.33 9.9 1.6 2.2 2 0 0 2 2 2 0 Microtubule-binding stalk of dynein motor MADF_DNA_bdg PF10545.9 GBG83377.1 - 0.12 12.7 3.1 0.24 11.8 0.0 3.0 2 1 1 3 3 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rab5-bind PF09311.11 GBG83377.1 - 0.15 11.5 35.7 0.042 13.2 13.1 2.8 1 1 1 2 2 2 0 Rabaptin-like protein COG5 PF10392.9 GBG83377.1 - 0.15 12.2 20.3 0.29 11.3 8.2 4.2 3 1 1 4 4 4 0 Golgi transport complex subunit 5 TPR_MLP1_2 PF07926.12 GBG83377.1 - 0.17 12.0 49.8 0.56 10.3 10.5 4.3 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Alanine_zipper PF11839.8 GBG83377.1 - 0.17 12.3 4.9 0.52 10.7 4.9 1.9 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein EzrA PF06160.12 GBG83377.1 - 0.39 8.8 33.6 0.014 13.6 18.1 2.7 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 GBG83377.1 - 0.48 10.5 57.8 0.04 14.0 17.5 5.5 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 GBG83377.1 - 0.68 9.3 43.4 1.2 8.5 26.2 3.3 1 1 2 3 3 3 0 Golgin subfamily A member 5 NPV_P10 PF05531.12 GBG83377.1 - 0.89 10.1 15.1 2 8.9 3.7 3.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1043 PF06295.12 GBG83377.1 - 1.4 8.9 8.6 5.3 7.1 8.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Spc42p PF11544.8 GBG83377.1 - 2.2 8.3 7.9 7.5 6.6 7.9 1.9 1 0 0 1 1 1 0 Spindle pole body component Spc42p SlyX PF04102.12 GBG83377.1 - 3 8.5 29.4 1.2 9.8 13.0 4.7 4 1 0 4 4 3 0 SlyX DUF4407 PF14362.6 GBG83377.1 - 4.2 6.6 31.3 14 4.9 25.7 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) FPP PF05911.11 GBG83377.1 - 4.6 5.3 38.4 0.95 7.6 23.3 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil AAA_13 PF13166.6 GBG83377.1 - 4.6 5.7 28.8 1 7.9 9.7 2.8 2 1 1 3 3 3 0 AAA domain DDE_Tnp_4 PF13359.6 GBG83378.1 - 5.1e-26 91.2 0.0 6.9e-25 87.6 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83378.1 - 3.9e-12 46.2 0.0 7.3e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83378.1 - 0.00074 19.2 0.7 3.7 7.1 0.1 3.1 3 0 0 3 3 3 2 Transposase DDE domain RVT_1 PF00078.27 GBG83380.1 - 9.1e-29 100.6 0.2 2.6e-28 99.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83380.1 - 4.9e-26 90.7 0.0 1.5e-25 89.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83380.1 - 2.4e-24 85.6 0.1 1.2e-23 83.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Baculo_PEP_C PF04513.12 GBG83380.1 - 0.2 11.7 3.7 0.54 10.3 3.7 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus USP8_interact PF08941.10 GBG83380.1 - 0.23 11.3 1.6 4.1 7.2 0.8 2.5 2 0 0 2 2 2 0 USP8 interacting Syntaxin-6_N PF09177.11 GBG83380.1 - 0.42 11.2 4.3 1.8 9.1 0.6 3.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.13 GBG83380.1 - 1.1 8.8 6.2 10 5.7 2.6 3.2 3 0 0 3 3 3 0 fzo-like conserved region SPACA9 PF15120.6 GBG83380.1 - 1.2 8.9 7.0 0.19 11.5 1.6 2.3 3 0 0 3 3 3 0 Sperm acrosome-associated protein 9 SNAPc19 PF15497.6 GBG83380.1 - 2.2 8.8 9.5 7.7 7.1 0.0 3.0 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Snapin_Pallidin PF14712.6 GBG83380.1 - 4.3 7.8 10.0 0.46 10.9 2.8 2.9 3 0 0 3 3 3 0 Snapin/Pallidin Pkinase_Tyr PF07714.17 GBG83381.1 - 3.9e-24 85.3 0.0 6.9e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83381.1 - 2.4e-21 76.3 0.0 4.8e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH PF17917.1 GBG83381.1 - 1.3e-20 73.7 0.0 2.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83381.1 - 3.4e-19 68.7 0.0 7.9e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83381.1 - 9.7e-16 58.0 0.0 1.8e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 GBG83381.1 - 0.00011 22.9 1.0 1.8 9.6 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1664 PF07889.12 GBG83381.1 - 7.8 6.6 5.9 26 4.9 0.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) SAPS PF04499.15 GBG83382.1 - 0.0041 16.0 8.8 0.0036 16.2 8.8 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Na_trans_assoc PF06512.13 GBG83382.1 - 0.011 16.1 19.8 0.012 15.9 19.8 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Endostatin PF06482.11 GBG83382.1 - 0.18 11.2 3.2 0.24 10.9 3.2 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Nop14 PF04147.12 GBG83382.1 - 0.32 9.2 41.9 0.37 8.9 41.9 1.0 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 GBG83382.1 - 0.75 8.5 24.9 1.3 7.7 24.9 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4407 PF14362.6 GBG83382.1 - 0.92 8.8 7.4 1.2 8.5 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SID-1_RNA_chan PF13965.6 GBG83382.1 - 1.1 7.5 4.2 1.1 7.6 4.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CCSAP PF15748.5 GBG83382.1 - 2.4 8.3 26.8 0.89 9.7 21.8 2.0 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated TCP PF03634.13 GBG83382.1 - 4.8 7.7 16.0 0.78 10.3 12.3 1.6 2 0 0 2 2 2 0 TCP family transcription factor AAA_11 PF13086.6 GBG83382.1 - 8.4 6.1 15.0 11 5.6 15.0 1.2 1 0 0 1 1 1 0 AAA domain SDA1 PF05285.12 GBG83382.1 - 8.8 5.6 45.7 12 5.2 45.7 1.2 1 0 0 1 1 1 0 SDA1 SelP_N PF04592.14 GBG83382.1 - 9.3 5.6 16.4 12 5.2 16.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NPR3 PF03666.13 GBG83382.1 - 9.8 4.8 22.0 14 4.3 22.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pkinase PF00069.25 GBG83383.1 - 1.6e-26 93.3 0.0 2.9e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83383.1 - 2.4e-24 86.0 0.0 5.2e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG83383.1 - 0.0076 17.1 13.2 0.45 11.5 0.0 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat TPR_MLP1_2 PF07926.12 GBG83383.1 - 0.013 15.5 12.6 0.013 15.5 12.6 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein eIF2A PF08662.11 GBG83383.1 - 0.1 12.5 0.0 0.35 10.7 0.0 1.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A FAM184 PF15665.5 GBG83383.1 - 0.28 11.0 27.2 9.5 5.9 19.0 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Macoilin PF09726.9 GBG83383.1 - 0.29 9.6 21.6 0.43 9.1 21.6 1.1 1 0 0 1 1 1 0 Macoilin family TEX13 PF15186.6 GBG83383.1 - 0.31 10.7 19.3 0.12 12.1 4.4 2.4 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family CENP-F_leu_zip PF10473.9 GBG83383.1 - 0.54 10.3 31.6 1.1 9.3 1.6 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TACC_C PF05010.14 GBG83383.1 - 2.6 7.8 21.1 0.21 11.3 8.5 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cluap1 PF10234.9 GBG83383.1 - 3.3 7.0 25.4 0.81 9.0 5.6 3.2 1 1 2 3 3 3 0 Clusterin-associated protein-1 Pkinase_Tyr PF07714.17 GBG83384.1 - 1.4e-49 168.7 0.0 2.9e-24 85.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG83384.1 - 5e-47 160.5 0.0 6.6e-23 81.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 GBG83384.1 - 3.8e-09 37.0 1.1 0.014 16.3 0.0 5.2 4 0 0 4 4 4 1 WD domain, G-beta repeat GAS PF13851.6 GBG83384.1 - 3.4e-05 23.3 4.1 3.4e-05 23.3 4.1 4.1 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding Nup160 PF11715.8 GBG83384.1 - 0.054 12.1 2.1 0.77 8.3 0.4 3.1 1 1 3 4 4 4 0 Nucleoporin Nup120/160 CENP-F_leu_zip PF10473.9 GBG83384.1 - 0.59 10.1 60.9 0.4 10.7 12.4 5.9 2 2 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lip_prot_lig_C PF10437.9 GBG83384.1 - 0.81 9.7 7.2 39 4.3 0.1 4.7 3 3 2 5 5 5 0 Bacterial lipoate protein ligase C-terminus Golgin_A5 PF09787.9 GBG83384.1 - 3.8 6.9 48.7 2.9 7.3 6.0 3.5 2 1 1 3 3 3 0 Golgin subfamily A member 5 RT_RNaseH PF17917.1 GBG83385.1 - 9.1e-33 112.7 0.0 1.8e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83385.1 - 3e-31 107.4 0.0 7.2e-31 106.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG83385.1 - 5.5e-15 55.6 0.1 2.5e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG83385.1 - 6.6e-08 32.5 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG83385.1 - 3.7e-05 23.9 0.0 8.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Ammonium_transp PF00909.21 GBG83387.1 - 2e-101 339.6 18.4 2.5e-101 339.3 18.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HdeA PF06411.11 GBG83387.1 - 1.7 8.8 3.6 3.4 7.9 0.2 2.5 2 0 0 2 2 2 0 HdeA/HdeB family DUF659 PF04937.15 GBG83389.1 - 4.9e-19 68.7 0.0 6.8e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVP_2 PF08284.11 GBG83390.1 - 3.3e-06 26.9 0.0 6.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG83390.1 - 2.2e-05 24.1 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG83390.1 - 3.2e-05 23.7 0.1 5.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83390.1 - 0.00033 21.2 0.0 0.00081 19.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83390.1 - 0.00048 20.7 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Pkinase PF00069.25 GBG83391.1 - 2.5e-12 46.7 0.0 4.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG83391.1 - 4.1e-11 43.2 0.8 0.0019 19.0 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 GBG83391.1 - 3e-10 39.8 0.0 5.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Rab5-bind PF09311.11 GBG83391.1 - 0.0021 17.5 10.0 0.0035 16.8 10.0 1.3 1 0 0 1 1 1 1 Rabaptin-like protein Nup160 PF11715.8 GBG83391.1 - 0.005 15.5 5.9 0.11 11.1 0.8 3.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GBG83391.1 - 0.045 14.1 0.2 0.48 10.8 0.3 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CENP-F_leu_zip PF10473.9 GBG83391.1 - 0.1 12.6 21.4 3.1 7.8 1.0 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 GBG83391.1 - 0.18 9.3 9.9 0.27 8.7 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BBP1_C PF15272.6 GBG83391.1 - 0.21 11.4 10.7 0.16 11.8 8.2 1.8 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal GAS PF13851.6 GBG83391.1 - 0.99 8.7 16.6 2.5 7.4 16.3 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-K PF11802.8 GBG83391.1 - 2.7 7.5 13.6 1.1 8.8 8.2 2.0 1 1 1 2 2 2 0 Centromere-associated protein K TPR_MLP1_2 PF07926.12 GBG83391.1 - 4.8 7.3 14.4 15 5.7 14.4 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phlebovirus_NSM PF07246.11 GBG83391.1 - 6.6 6.0 12.5 4.3 6.6 10.6 1.6 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Golgin_A5 PF09787.9 GBG83391.1 - 7.5 5.9 17.5 47 3.3 17.6 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 RT_RNaseH_2 PF17919.1 GBG83392.1 - 2.1e-11 43.7 0.2 6.3e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83392.1 - 1.5e-09 37.7 0.1 2.7e-09 36.9 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83392.1 - 0.00016 22.0 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG83392.1 - 0.92 7.7 12.4 1.2 7.3 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG83392.1 - 1.7 6.8 13.2 2.4 6.3 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG83392.1 - 2 7.7 14.7 2.6 7.4 14.7 1.1 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 GBG83392.1 - 2.6 8.0 19.7 4.5 7.2 19.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RR_TM4-6 PF06459.12 GBG83392.1 - 3.5 7.4 8.4 5.3 6.8 8.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 GBG83392.1 - 4.5 5.3 5.4 5.7 4.9 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BUD22 PF09073.10 GBG83392.1 - 4.9 6.4 17.6 7 5.9 17.6 1.1 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 GBG83392.1 - 5.4 6.3 9.3 8 5.8 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PGA2 PF07543.12 GBG83392.1 - 8.3 6.4 10.3 18 5.3 10.3 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Pkinase_Tyr PF07714.17 GBG83393.1 - 2.7e-23 82.6 0.0 4.7e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83393.1 - 6.4e-21 74.9 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG83393.1 - 2.3e-11 44.1 3.0 3.3e-05 24.6 0.1 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG83393.1 - 0.0012 19.1 0.0 0.24 11.7 0.0 3.3 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HMMR_N PF15905.5 GBG83393.1 - 0.021 14.3 6.1 0.039 13.4 6.1 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3584 PF12128.8 GBG83393.1 - 0.029 11.9 8.9 0.041 11.4 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 GBG83393.1 - 0.082 11.8 6.9 0.14 11.0 6.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 GBG83393.1 - 0.14 12.2 16.8 1.1 9.3 11.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD PF14073.6 GBG83393.1 - 0.16 12.0 10.3 0.34 10.9 10.3 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Lipoprotein_20 PF13942.6 GBG83393.1 - 0.2 11.6 4.8 0.41 10.5 4.8 1.5 1 0 0 1 1 1 0 YfhG lipoprotein GAS PF13851.6 GBG83393.1 - 0.57 9.5 12.1 1.1 8.6 12.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 GBG83393.1 - 1.2 9.3 11.2 2.1 8.5 11.2 1.4 1 0 0 1 1 1 0 Tropomyosin like APG6_N PF17675.1 GBG83393.1 - 1.9 9.0 14.5 0.46 11.0 9.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 GBG83393.1 - 2.5 8.2 14.4 16 5.5 14.2 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 GBG83393.1 - 2.5 7.6 12.6 4.5 6.8 12.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein bZIP_1 PF00170.21 GBG83393.1 - 8.1 6.6 8.5 4.2 7.5 3.2 2.8 2 1 1 3 3 3 0 bZIP transcription factor RT_RNaseH PF17917.1 GBG83394.1 - 2.2e-24 85.8 0.0 3.3e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83394.1 - 5.9e-17 61.5 0.0 9.6e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase OGG_N PF07934.12 GBG83394.1 - 0.0044 17.1 0.0 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain DUF4140 PF13600.6 GBG83395.1 - 0.00011 22.5 0.1 0.00018 21.9 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) WD40 PF00400.32 GBG83395.1 - 0.003 18.4 7.4 0.0032 18.3 0.1 4.2 5 1 0 5 5 5 1 WD domain, G-beta repeat Vac_Fusion PF02346.16 GBG83395.1 - 0.0038 16.8 2.5 0.007 16.0 2.5 1.5 1 0 0 1 1 1 1 Chordopoxvirus multifunctional envelope protein A27 PKcGMP_CC PF16808.5 GBG83395.1 - 0.024 14.5 11.6 0.3 11.0 3.0 2.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HemX PF04375.14 GBG83395.1 - 0.033 13.5 0.4 0.053 12.8 0.4 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CorA PF01544.18 GBG83395.1 - 0.033 13.5 1.4 0.05 12.9 1.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pox_A_type_inc PF04508.12 GBG83395.1 - 0.046 13.6 7.4 1.3 9.0 2.2 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Jnk-SapK_ap_N PF09744.9 GBG83395.1 - 0.082 13.1 6.3 0.12 12.5 6.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 GBG83395.1 - 0.13 11.3 1.6 0.18 10.9 1.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4404 PF14357.6 GBG83395.1 - 0.14 12.8 2.3 0.29 11.8 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 GBG83395.1 - 0.2 11.7 1.6 0.37 10.8 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 GBG83395.1 - 1.9 8.5 10.0 3.1 7.8 10.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit PEX11 PF05648.14 GBG83396.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Ammonium_transp PF00909.21 GBG83397.1 - 3.9e-113 378.2 25.3 5.1e-113 377.8 25.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SID-1_RNA_chan PF13965.6 GBG83397.1 - 0.39 9.1 1.4 0.74 8.2 1.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S64 PF08192.11 GBG83398.1 - 1.3 7.5 7.4 1.4 7.3 7.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Na_trans_assoc PF06512.13 GBG83398.1 - 5.3 7.3 13.7 8.5 6.6 13.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated XRN_M PF17846.1 GBG83398.1 - 8.6 5.2 10.0 12 4.7 10.0 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Ammonium_transp PF00909.21 GBG83399.1 - 1.2e-103 346.9 23.5 1.4e-103 346.7 23.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 GBG83400.1 - 1.1e-92 310.9 18.1 1.4e-92 310.5 18.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 GBG83401.1 - 1.5e-45 155.6 11.6 5e-32 111.1 2.4 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family Retrotrans_gag PF03732.17 GBG83404.1 - 0.034 14.4 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Rep_fac-A_C PF08646.10 GBG83405.1 - 4.9e-31 107.4 0.1 1.4e-29 102.8 0.0 2.5 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 GBG83405.1 - 9.5e-21 73.6 0.1 3.4e-20 71.8 0.0 2.0 3 0 0 3 3 3 1 Replication protein A OB domain zf-CCHC PF00098.23 GBG83405.1 - 1.6e-18 65.8 37.8 2e-07 30.8 2.3 5.0 5 0 0 5 5 5 4 Zinc knuckle tRNA_anti-codon PF01336.25 GBG83405.1 - 2.3e-12 46.7 0.1 3.3e-10 39.8 0.0 3.1 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain zf-CCHC_2 PF13696.6 GBG83405.1 - 6.4e-07 29.1 44.7 3e-05 23.7 2.8 5.1 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.6 GBG83405.1 - 2.5e-05 24.1 22.8 0.17 11.9 0.6 4.6 3 1 1 4 4 4 4 Zinc knuckle CDC24_OB3 PF17244.2 GBG83405.1 - 0.011 15.5 0.0 0.38 10.4 0.0 2.5 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 zf-CCHC_5 PF14787.6 GBG83405.1 - 0.033 13.9 24.7 2.4 8.0 1.8 4.6 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger tRNA_anti_2 PF13742.6 GBG83405.1 - 0.077 13.2 0.1 18 5.6 0.0 2.6 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain zf-CCHC_4 PF14392.6 GBG83405.1 - 1.2 9.0 25.1 1.1 9.1 0.3 4.7 4 1 1 5 5 5 0 Zinc knuckle Bromodomain PF00439.25 GBG83407.1 - 1.1e-24 86.3 0.1 2.4e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain ATG16 PF08614.11 GBG83408.1 - 3.4e-20 73.1 17.4 4.7e-20 72.7 17.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 GBG83408.1 - 1.1e-14 54.6 8.4 0.00021 22.0 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG83408.1 - 2.2e-05 24.7 0.1 0.0011 19.2 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG83408.1 - 0.03 13.3 0.0 0.48 9.3 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein APG6_N PF17675.1 GBG83408.1 - 1.8 9.1 22.8 0.75 10.3 7.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 GBG83408.1 - 3.7 7.6 11.4 0.31 11.1 6.0 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding RNase_T PF00929.24 GBG83409.1 - 2.5e-09 37.9 0.0 3.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 GBG83409.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 2 0 0 2 2 2 0 3'-5' exonuclease GPS2_interact PF15784.5 GBG83410.1 - 0.55 10.7 15.7 0.083 13.3 3.9 3.7 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain Glutaredoxin PF00462.24 GBG83412.1 - 4.7e-10 39.5 1.7 8.5e-10 38.7 0.1 2.3 2 0 0 2 2 2 1 Glutaredoxin Zip PF02535.22 GBG83412.1 - 1.6 7.9 3.4 3.8 6.6 3.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Sar8_2 PF03058.14 GBG83413.1 - 1.8 9.2 5.8 0.21 12.1 0.6 2.1 2 0 0 2 2 2 0 Sar8.2 family Amino_oxidase PF01593.24 GBG83415.1 - 2.7e-65 221.5 0.0 3.4e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG83415.1 - 1.3e-15 57.4 0.1 3.2e-15 56.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GBG83415.1 - 1.4e-05 24.3 0.1 0.00067 18.8 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain MCRA PF06100.11 GBG83415.1 - 0.00015 20.7 0.0 0.014 14.2 0.0 2.1 2 0 0 2 2 2 2 MCRA family DAO PF01266.24 GBG83415.1 - 0.00022 20.9 0.1 0.00059 19.5 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GBG83415.1 - 0.0007 18.9 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GBG83415.1 - 0.0017 17.8 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GBG83415.1 - 0.002 17.4 0.4 0.013 14.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GBG83415.1 - 0.0044 15.8 0.1 0.0088 14.8 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 GBG83415.1 - 0.0087 16.1 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GBG83415.1 - 0.048 14.2 0.1 0.13 12.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Atu4866 PF11512.8 GBG83417.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 DUF659 PF04937.15 GBG83418.1 - 1.9e-39 135.0 0.0 3.8e-39 134.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG83418.1 - 0.056 13.5 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 BED zinc finger Peptidase_C2 PF00648.21 GBG83419.1 - 6.9e-273 901.8 0.0 2.9e-74 249.8 0.0 5.2 5 0 0 5 5 5 5 Calpain family cysteine protease DUF659 PF04937.15 GBG83421.1 - 1.2e-33 116.1 0.0 1.9e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4311 PF14188.6 GBG83421.1 - 0.02 14.7 0.9 0.083 12.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4311) DUF4509 PF14970.6 GBG83422.1 - 7.9e-18 65.1 0.0 2.8e-15 56.7 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4509) CENP-B_dimeris PF09026.10 GBG83422.1 - 0.066 13.6 5.4 0.036 14.4 1.9 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1645 PF07816.11 GBG83422.1 - 0.079 13.5 0.1 0.079 13.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) FAM176 PF14851.6 GBG83422.1 - 0.12 12.1 4.4 0.17 11.6 0.1 2.5 2 0 0 2 2 2 0 FAM176 family DUF4509 PF14970.6 GBG83423.1 - 6.8e-18 65.3 0.0 2.7e-15 56.8 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4509) CENP-B_dimeris PF09026.10 GBG83423.1 - 0.069 13.5 5.6 0.034 14.5 1.9 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1645 PF07816.11 GBG83423.1 - 0.073 13.7 0.1 0.073 13.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) FAM176 PF14851.6 GBG83423.1 - 0.099 12.3 4.4 0.15 11.7 0.1 2.5 2 0 0 2 2 2 0 FAM176 family Cnn_1N PF07989.11 GBG83425.1 - 0.013 15.6 2.2 0.032 14.4 2.2 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Adap_comp_sub PF00928.21 GBG83426.1 - 5.6e-86 288.2 0.0 6.9e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GBG83426.1 - 0.00017 21.5 0.2 0.00028 20.8 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ank_2 PF12796.7 GBG83427.1 - 4.7e-19 68.8 0.0 2.3e-09 37.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GBG83427.1 - 4e-14 52.3 0.0 5.3e-05 23.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GBG83427.1 - 6.5e-14 50.7 0.0 0.00013 22.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GBG83427.1 - 8.8e-14 51.4 0.1 3.5e-06 27.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GBG83427.1 - 2e-13 50.5 0.0 6.3e-06 26.6 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ist1 PF03398.14 GBG83428.1 - 2.8e-57 193.2 0.5 4.6e-57 192.5 0.2 1.5 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway gag-asp_proteas PF13975.6 GBG83429.1 - 3.3e-07 30.8 0.0 9.1e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83429.1 - 4e-06 27.4 0.0 1.2e-05 25.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG83429.1 - 0.0048 16.7 0.1 0.0092 15.8 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83429.1 - 0.0054 16.5 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83432.1 - 6.1e-07 30.0 0.0 1.6e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83432.1 - 6.8e-06 26.6 0.1 2.2e-05 24.9 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG83432.1 - 0.0018 18.0 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83432.1 - 0.0083 15.9 0.2 0.015 15.1 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG83432.1 - 0.049 13.7 2.4 0.094 12.8 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle HAT_KAT11 PF08214.11 GBG83435.1 - 9.8e-30 104.0 0.2 9.8e-30 104.0 0.2 2.4 2 1 0 2 2 2 1 Histone acetylation protein zf-TAZ PF02135.16 GBG83435.1 - 1.7e-19 70.0 34.2 2.4e-12 47.1 10.3 5.5 6 0 0 6 6 6 2 TAZ zinc finger ZZ PF00569.17 GBG83435.1 - 4.9e-07 29.5 10.7 4.9e-07 29.5 10.7 4.1 4 0 0 4 4 4 2 Zinc finger, ZZ type PHD PF00628.29 GBG83435.1 - 1.9e-06 27.6 9.7 1.9e-06 27.6 9.7 6.3 6 2 0 6 6 6 1 PHD-finger PhyH PF05721.13 GBG83436.1 - 5.4e-33 115.0 0.0 7.7e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 GBG83436.1 - 0.00081 20.2 0.0 0.0018 19.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 GBG83436.1 - 0.0039 17.6 0.0 0.0073 16.7 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase APC_N_CC PF16689.5 GBG83437.1 - 0.0037 17.3 5.3 0.047 13.8 0.3 2.8 2 0 0 2 2 2 2 Coiled-coil N-terminus of APC, dimerisation domain Retrotrans_gag PF03732.17 GBG83439.1 - 0.00066 19.9 0.1 0.00066 19.9 0.1 2.2 3 0 0 3 3 3 1 Retrotransposon gag protein Retrotrans_gag PF03732.17 GBG83440.1 - 6.5e-05 23.1 0.3 0.00026 21.2 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG83440.1 - 0.96 9.3 4.3 2.2 8.1 2.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) Paf1 PF03985.13 GBG83441.1 - 0.3 10.1 7.3 0.4 9.6 7.3 1.1 1 0 0 1 1 1 0 Paf1 Prok-RING_2 PF14445.6 GBG83441.1 - 0.72 10.1 4.7 5.3 7.3 0.3 3.0 1 1 2 3 3 3 0 Prokaryotic RING finger family 2 S1-P1_nuclease PF02265.16 GBG83442.1 - 1.8e-64 218.0 1.8 1.9e-39 136.0 0.0 3.2 3 0 0 3 3 3 2 S1/P1 Nuclease Exonuc_VII_L PF02601.15 GBG83442.1 - 2 7.9 5.4 3.3 7.2 5.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3391 PF11871.8 GBG83442.1 - 3.1 8.3 6.4 12 6.5 4.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Mito_fiss_reg PF05308.11 GBG83442.1 - 4.4 7.3 19.0 2.1 8.3 9.0 2.2 1 1 1 2 2 2 0 Mitochondrial fission regulator 2OG-FeII_Oxy PF03171.20 GBG83443.1 - 3.9e-22 78.7 0.0 6.2e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GFO_IDH_MocA PF01408.22 GBG83444.1 - 0.026 15.3 0.0 0.055 14.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 GBG83444.1 - 0.027 15.1 0.0 0.075 13.6 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3719 PF12516.8 GBG83444.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) SARAF PF06682.12 GBG83445.1 - 0.48 10.0 6.1 0.6 9.7 6.1 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis G0-G1_switch_2 PF15103.6 GBG83445.1 - 2.9 8.3 7.0 5.4 7.5 7.0 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 Peptidase_M8 PF01457.16 GBG83446.1 - 1.4e-07 30.6 0.0 3.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Leishmanolysin Aspzincin_M35 PF14521.6 GBG83446.1 - 0.033 14.7 0.2 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase nec1 PF10379.9 GBG83446.1 - 0.27 10.7 1.1 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Virulence protein nec1 rve PF00665.26 GBG83447.1 - 8.3e-10 38.9 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG83447.1 - 0.00066 19.5 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 GBG83448.1 - 4.6e-06 27.1 0.0 2.8e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83448.1 - 5.2e-06 27.0 0.0 2.3e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG83448.1 - 9.6e-05 22.2 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83448.1 - 0.00028 20.7 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG83448.1 - 0.061 13.6 4.9 0.98 9.7 0.2 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG83449.1 - 5.7e-30 103.3 0.0 2e-29 101.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83449.1 - 1e-29 102.9 0.1 4.4e-29 100.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83449.1 - 9.6e-20 70.5 0.4 2.1e-19 69.3 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_1 PF03184.19 GBG83449.1 - 2.9e-09 36.8 0.0 7.1e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2 PF09337.10 GBG83449.1 - 0.00024 21.3 0.4 0.0008 19.6 0.1 2.1 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 GBG83449.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) LAP1C PF05609.12 GBG83449.1 - 7 5.6 19.7 10 5.1 19.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RT_RNaseH_2 PF17919.1 GBG83450.1 - 6.3e-30 103.2 0.0 1.5e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83450.1 - 2.9e-26 91.8 0.0 9.2e-26 90.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG83450.1 - 6e-17 61.9 0.0 8.7e-15 55.0 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain Peptidase_M8 PF01457.16 GBG83450.1 - 3.1e-14 52.6 0.0 4.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin RVT_1 PF00078.27 GBG83450.1 - 3.6e-10 39.8 0.1 6.9e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG83450.1 - 4.2e-09 36.3 0.0 1.1e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83450.1 - 8.5e-06 26.3 0.0 2.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83450.1 - 0.00027 21.4 0.0 0.00092 19.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83450.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease eIF-1a PF01176.19 GBG83450.1 - 0.0039 17.0 0.1 0.051 13.4 0.1 2.3 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 rve_3 PF13683.6 GBG83450.1 - 0.014 15.1 0.0 0.4 10.5 0.0 3.2 2 0 0 2 2 2 0 Integrase core domain Mid2 PF04478.12 GBG83453.1 - 0.00036 20.4 0.1 0.0052 16.6 0.0 2.2 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor RelA_SpoT PF04607.17 GBG83454.1 - 1.4e-23 83.4 0.0 5.3e-23 81.5 0.0 2.1 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 GBG83454.1 - 1.3e-18 67.2 1.3 2.4e-18 66.4 1.3 1.5 1 0 0 1 1 1 1 HD domain EF-hand_1 PF00036.32 GBG83454.1 - 1.7e-12 45.9 4.2 1.8e-07 30.2 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GBG83454.1 - 3e-12 45.4 0.5 1.2e-07 30.9 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GBG83454.1 - 3.5e-12 46.6 0.0 5.6e-11 42.7 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG83454.1 - 1.9e-10 39.8 0.7 1.3e-06 27.9 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GBG83454.1 - 1.1e-08 34.8 1.3 4.1e-05 23.3 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain pair RRM_1 PF00076.22 GBG83454.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPARC_Ca_bdg PF10591.9 GBG83454.1 - 0.0072 16.6 0.0 0.028 14.7 0.0 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GBG83454.1 - 0.11 12.9 0.1 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain RVT_1 PF00078.27 GBG83455.1 - 4.9e-07 29.5 0.0 8.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SICA_C PF12879.7 GBG83455.1 - 0.15 12.0 3.7 0.086 12.9 0.8 2.1 2 0 0 2 2 2 0 SICA C-terminal inner membrane domain Integrase_H2C2 PF17921.1 GBG83456.1 - 5.3e-16 58.5 0.5 1.3e-15 57.3 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain TPR_2 PF07719.17 GBG83456.1 - 1.9e-13 49.4 20.2 0.0063 16.5 1.4 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG83456.1 - 4.7e-12 45.1 10.4 0.074 13.3 0.1 7.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 GBG83456.1 - 1.1e-10 41.0 9.6 0.018 14.7 0.0 6.3 6 0 0 6 6 6 3 TPR repeat TPR_14 PF13428.6 GBG83456.1 - 1.7e-09 37.7 30.1 0.018 15.8 0.4 8.5 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 GBG83456.1 - 3.1e-08 33.8 25.7 1.6 9.1 0.2 7.4 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 GBG83456.1 - 1.2e-07 32.2 25.9 0.0056 17.2 0.5 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG83456.1 - 1.3e-06 28.0 16.3 1.5 8.8 0.4 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 GBG83456.1 - 1.8e-05 25.3 34.4 0.03 15.0 0.9 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat DNA_pack_N PF02500.15 GBG83456.1 - 0.017 15.0 0.1 0.043 13.6 0.1 1.6 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus RVP_2 PF08284.11 GBG83456.1 - 0.025 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease TPR_7 PF13176.6 GBG83456.1 - 0.061 13.4 12.8 11 6.4 0.2 6.4 6 0 0 6 6 5 0 Tetratricopeptide repeat gag-asp_proteas PF13975.6 GBG83456.1 - 0.065 13.8 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease ANAPC3 PF12895.7 GBG83456.1 - 0.26 11.5 13.8 1.3 9.3 0.1 5.2 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1664 PF07889.12 GBG83456.1 - 0.44 10.6 4.7 19 5.3 3.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TPR_9 PF13371.6 GBG83456.1 - 1.3 9.2 13.0 16 5.7 0.2 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG83456.1 - 1.5 8.8 15.7 10 6.2 0.4 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat PRAI PF00697.22 GBG83457.1 - 6.2e-13 49.0 0.0 8.3e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Histone PF00125.24 GBG83464.1 - 1.1e-20 74.3 0.8 3.4e-20 72.7 0.8 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Myb_DNA-bind_4 PF13837.6 GBG83464.1 - 6e-05 23.3 1.9 0.00017 21.9 1.9 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG83464.1 - 0.021 14.9 0.2 0.044 13.9 0.2 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2584 PF10763.9 GBG83465.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) RVT_1 PF00078.27 GBG83466.1 - 2.7e-35 121.9 0.1 4.6e-35 121.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83466.1 - 3.1e-30 104.6 0.0 8.8e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83466.1 - 8.2e-30 102.8 0.0 2e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG83466.1 - 3.5e-06 26.8 0.0 7.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83466.1 - 5.2e-05 23.8 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83466.1 - 0.033 14.7 0.0 0.12 13.0 0.0 2.0 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG83466.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Med9 PF07544.13 GBG83466.1 - 0.88 9.7 10.2 2.3 8.4 0.5 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Retrotrans_gag PF03732.17 GBG83467.1 - 0.013 15.7 1.9 0.022 15.0 0.1 2.2 2 1 0 2 2 2 0 Retrotransposon gag protein BTP PF05232.12 GBG83468.1 - 7.5 6.7 9.3 1.8 8.7 3.9 2.7 2 1 0 2 2 2 0 Chlorhexidine efflux transporter RVT_1 PF00078.27 GBG83469.1 - 1.2e-23 83.8 0.1 2e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83469.1 - 1.1e-13 51.1 0.2 9.7e-13 48.0 0.0 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG83469.1 - 9e-13 48.5 0.0 2.8e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG83469.1 - 3.6e-12 46.0 0.0 7.6e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG83469.1 - 0.00016 21.8 0.0 0.00052 20.2 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger Na_trans_assoc PF06512.13 GBG83470.1 - 0.0079 16.5 9.1 0.0079 16.5 9.1 1.7 2 0 0 2 2 2 1 Sodium ion transport-associated Zip PF02535.22 GBG83470.1 - 0.69 9.1 3.8 1 8.5 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 GBG83470.1 - 1.2 8.5 18.8 2.3 7.6 18.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 GBG83470.1 - 1.5 7.5 12.8 2.3 6.9 12.8 1.2 1 0 0 1 1 1 0 Presenilin K_channel_TID PF07941.11 GBG83470.1 - 3 8.4 16.3 2 8.9 3.6 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Nop14 PF04147.12 GBG83470.1 - 8.1 4.5 30.4 13 3.8 30.4 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_S6 PF01250.17 GBG83472.1 - 9.6e-16 57.8 0.0 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 zf-CCHC PF00098.23 GBG83473.1 - 0.026 14.6 2.4 0.043 13.9 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG83475.1 - 0.1 12.3 0.3 0.24 11.2 0.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Lamprin PF06403.11 GBG83475.1 - 1.4 8.9 14.5 3.5 7.6 14.5 1.6 1 0 0 1 1 1 0 Lamprin SICA_C PF12879.7 GBG83476.1 - 0.36 10.8 2.2 0.9 9.6 2.2 1.6 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain Myb_DNA-bind_4 PF13837.6 GBG83479.1 - 1.1e-05 25.7 1.8 6e-05 23.3 1.0 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG83480.1 - 6.2e-29 100.7 0.0 8.5e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83480.1 - 7.7e-16 58.3 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83480.1 - 0.03 14.0 0.1 2.3 7.8 0.2 2.3 2 0 0 2 2 2 0 Transposase DDE domain Retrotrans_gag PF03732.17 GBG83481.1 - 0.001 19.3 0.0 0.001 19.3 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein SlyX PF04102.12 GBG83481.1 - 0.0055 17.3 2.0 0.0055 17.3 2.0 4.4 4 1 1 5 5 5 2 SlyX TRPM_tetra PF16519.5 GBG83481.1 - 2.8 8.1 5.9 12 6.1 0.1 3.1 2 1 0 2 2 2 0 Tetramerisation domain of TRPM DUF16 PF01519.16 GBG83481.1 - 7.6 7.1 9.7 11 6.6 0.9 3.2 3 1 0 3 3 3 0 Protein of unknown function DUF16 Myb_DNA-bind_4 PF13837.6 GBG83483.1 - 1.4e-08 35.0 3.9 2.8e-08 34.0 3.5 1.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG83483.1 - 0.00071 19.6 4.3 0.0018 18.3 2.8 2.1 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83483.1 - 0.029 14.7 3.6 0.096 13.0 2.4 2.0 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Integrase_H2C2 PF17921.1 GBG83485.1 - 2.3e-15 56.4 0.1 5.1e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83485.1 - 2.9e-06 27.4 0.0 5.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG83485.1 - 0.0032 17.7 0.0 0.0068 16.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger SICA_C PF12879.7 GBG83485.1 - 0.061 13.4 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain Mannosyl_trans3 PF11051.8 GBG83487.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative WD40 PF00400.32 GBG83488.1 - 1.7e-10 41.3 0.4 0.045 14.6 0.1 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG83488.1 - 1.9e-08 34.5 0.0 0.0031 17.8 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GBG83488.1 - 0.0077 14.8 0.0 0.015 13.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 GBG83488.1 - 0.12 11.7 0.0 15 4.8 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain IBR PF01485.21 GBG83489.1 - 5.6e-13 48.9 22.4 7.9e-10 38.8 3.7 4.3 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain Asp_protease PF09668.10 GBG83490.1 - 0.15 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG83490.1 - 0.27 11.4 1.9 0.51 10.5 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG83491.1 - 1e-32 112.5 0.0 2.6e-32 111.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83491.1 - 1.5e-31 108.4 0.0 1e-30 105.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83491.1 - 4.8e-09 36.2 0.1 1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG83491.1 - 5e-08 32.7 0.1 7.9e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG83491.1 - 6.7e-06 26.2 0.1 1.6e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG83491.1 - 0.00024 21.3 0.0 0.00075 19.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 GBG83491.1 - 0.18 11.8 0.4 0.56 10.2 0.4 1.8 1 0 0 1 1 1 0 Integrase Zinc binding domain EAL PF00563.20 GBG83491.1 - 0.2 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 EAL domain MULE PF10551.9 GBG83492.1 - 1.7e-21 76.5 1.4 6.1e-21 74.6 0.0 2.6 3 0 0 3 3 3 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG83492.1 - 1.2e-14 54.1 0.4 3.5e-14 52.5 0.4 1.8 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.18 GBG83492.1 - 1.4e-08 34.0 0.0 2.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.17 GBG83492.1 - 3.5e-05 23.4 0.1 0.0001 21.9 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger zf-CCHC_2 PF13696.6 GBG83492.1 - 0.0016 18.2 0.2 0.0043 16.8 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 GBG83492.1 - 0.23 11.2 3.0 0.72 9.6 3.0 1.9 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 GBG83492.1 - 2.3 8.0 8.6 0.078 12.7 1.2 2.4 3 0 0 3 3 3 0 Zinc knuckle Pro_isomerase PF00160.21 GBG83493.1 - 1.3e-22 80.8 0.0 2.8e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arg_decarbox_C PF17944.1 GBG83493.1 - 0.17 12.5 0.1 14 6.3 0.0 2.6 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension gag-asp_proteas PF13975.6 GBG83494.1 - 1.2e-07 32.2 0.0 3e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83494.1 - 5.3e-07 30.2 0.0 1.2e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83494.1 - 5.5e-06 26.2 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG83494.1 - 0.0014 18.9 0.4 0.0014 18.9 0.4 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG83494.1 - 0.0073 16.1 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Lipin_mid PF16876.5 GBG83494.1 - 0.035 14.2 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain RT_RNaseH_2 PF17919.1 GBG83498.1 - 1.7e-31 108.2 0.0 1.7e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83498.1 - 7.5e-30 103.3 0.0 1.6e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83498.1 - 7.6e-28 97.5 0.0 1.2e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG83498.1 - 0.14 12.2 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L34 Pkinase PF00069.25 GBG83499.1 - 5.6e-46 157.0 0.0 9.1e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83499.1 - 1.2e-45 155.8 0.0 2.1e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Beta_helix PF13229.6 GBG83499.1 - 0.0024 17.7 2.4 0.0064 16.4 2.4 1.7 1 0 0 1 1 1 1 Right handed beta helix region Kinase-like PF14531.6 GBG83499.1 - 0.0058 16.0 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GBG83499.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 GBG83499.1 - 0.083 12.5 0.4 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 UPF0020 PF01170.18 GBG83500.1 - 9.1e-11 41.8 0.1 1.1e-09 38.2 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 GBG83500.1 - 0.0023 17.7 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.15 GBG83500.1 - 0.088 12.5 0.0 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.15 GBG83500.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRIMA1 PF16101.5 GBG83500.1 - 5.2 7.1 11.7 11 6.1 11.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MTHFR PF02219.17 GBG83501.1 - 6.8e-122 406.3 0.0 9.5e-122 405.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase NOA36 PF06524.12 GBG83502.1 - 4.5 6.5 11.4 4.9 6.4 11.4 1.2 1 0 0 1 1 1 0 NOA36 protein Roughex PF06020.11 GBG83502.1 - 9.9 5.1 6.2 10 5.1 6.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein ABC1 PF03109.16 GBG83503.1 - 5.3e-31 107.2 0.0 8.7e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Brix PF04427.18 GBG83504.1 - 1.3e-23 84.2 0.0 2e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Brix domain Histone PF00125.24 GBG83505.1 - 9.7e-22 77.7 0.7 9.7e-22 77.7 0.7 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone PF00125.24 GBG83506.1 - 6.1e-22 78.4 0.7 6.1e-22 78.4 0.7 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG83506.1 - 0.14 12.6 0.4 0.61 10.5 0.1 2.1 2 0 0 2 2 2 0 CENP-S protein Mito_carr PF00153.27 GBG83507.1 - 1.9e-69 229.6 6.8 3.7e-22 78.0 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 GBG83509.1 - 1.5e-23 83.6 0.0 3.9e-23 82.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83509.1 - 6.3e-21 74.8 0.0 1.2e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Retrotrans_gag PF03732.17 GBG83509.1 - 0.011 15.9 0.4 0.038 14.3 0.4 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein APH PF01636.23 GBG83509.1 - 1.3 8.9 10.0 1 9.2 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family TbpB_B_D PF01298.18 GBG83510.1 - 0.28 11.6 2.5 0.49 10.8 1.8 1.7 1 1 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B SspB PF04386.13 GBG83510.1 - 0.38 10.6 4.9 1.1 9.2 4.9 1.8 1 0 0 1 1 1 0 Stringent starvation protein B Nop14 PF04147.12 GBG83510.1 - 0.51 8.5 14.7 0.7 8.0 14.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG83510.1 - 0.56 8.4 10.1 0.76 8.0 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 GBG83510.1 - 3.3 7.4 8.4 6.8 6.3 8.4 1.5 1 0 0 1 1 1 0 FAM176 family CobT PF06213.12 GBG83510.1 - 3.4 7.0 14.9 5.4 6.3 14.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 GBG83510.1 - 5.2 6.4 18.0 7.5 5.9 18.0 1.2 1 0 0 1 1 1 0 SDA1 RT_RNaseH_2 PF17919.1 GBG83511.1 - 5.5e-52 174.0 0.0 4.2e-28 97.3 0.1 3.6 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83511.1 - 2.3e-38 130.7 0.0 4e-26 91.4 0.3 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83511.1 - 6.1e-31 107.7 0.0 1.1e-30 106.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83511.1 - 1.5e-19 69.8 0.2 3.8e-19 68.6 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83511.1 - 3.7e-16 59.4 0.0 1e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG83511.1 - 0.0029 17.8 0.0 0.0088 16.2 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG83513.1 - 2.4e-28 99.2 0.0 3.4e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83513.1 - 4.9e-08 33.5 0.0 8.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83513.1 - 5.2e-07 30.1 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG83513.1 - 3e-05 23.8 0.0 5.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83513.1 - 4.7e-05 23.2 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease HIP1_clath_bdg PF16515.5 GBG83514.1 - 0.0032 18.1 5.1 0.0032 18.1 5.1 3.4 3 1 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Retrotrans_gag PF03732.17 GBG83514.1 - 0.012 15.8 7.5 0.016 15.5 0.0 3.0 3 1 0 3 3 3 0 Retrotransposon gag protein SPACA9 PF15120.6 GBG83514.1 - 0.013 15.3 1.1 0.03 14.1 1.1 1.5 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 LMBR1 PF04791.16 GBG83514.1 - 0.099 11.5 5.1 0.14 11.1 5.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2730 PF10805.8 GBG83514.1 - 0.2 11.7 2.1 2.9 8.0 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DASH_Dad3 PF08656.10 GBG83514.1 - 0.38 10.9 5.5 9 6.5 2.4 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 SPARC_Ca_bdg PF10591.9 GBG83514.1 - 3 8.2 6.6 1.1 9.6 3.0 2.1 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region M PF02370.16 GBG83514.1 - 3.5 8.5 9.8 4.5 8.2 4.6 3.5 2 0 0 2 2 2 0 M protein repeat MULE PF10551.9 GBG83515.1 - 1.4e-14 54.2 0.0 3.2e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG83515.1 - 4.8e-11 42.5 0.1 2.4e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 MuDR family transposase Asp_protease_2 PF13650.6 GBG83515.1 - 0.00014 22.4 0.0 0.00031 21.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83515.1 - 0.00078 20.0 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Transposase_mut PF00872.18 GBG83515.1 - 0.007 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Asp_protease PF09668.10 GBG83515.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Glyco_transf_92 PF01697.27 GBG83517.1 - 5e-22 78.8 0.7 2.1e-19 70.2 0.2 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 GBG83517.1 - 6.2e-09 36.3 1.0 3e-08 34.1 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chorion_2 PF03964.15 GBG83517.1 - 1.3 9.9 12.7 0.045 14.6 4.6 2.8 3 0 0 3 3 3 0 Chorion family 2 Mito_fiss_reg PF05308.11 GBG83517.1 - 1.4 8.9 6.4 3.8 7.5 6.4 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 GBG83517.1 - 5.8 6.3 9.3 15 5.0 9.3 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG83517.1 - 7.6 6.6 7.6 16 5.6 7.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Myb_DNA-bind_4 PF13837.6 GBG83519.1 - 1.1e-05 25.7 1.2 2.1e-05 24.8 1.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Lon_C PF05362.13 GBG83520.1 - 4.5e-77 258.2 0.2 9.2e-77 257.2 0.2 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 GBG83520.1 - 1.4e-25 90.4 0.0 2.7e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 GBG83520.1 - 6.5e-20 71.9 0.0 1.6e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GBG83520.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 GBG83520.1 - 2.2e-05 24.3 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 GBG83520.1 - 4.9e-05 23.8 0.0 0.00035 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 GBG83520.1 - 6.2e-05 23.2 0.0 0.00034 20.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GBG83520.1 - 9.5e-05 22.2 0.0 0.00029 20.6 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG83520.1 - 0.00017 21.8 0.2 0.0074 16.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 GBG83520.1 - 0.00045 19.2 0.0 0.0011 17.9 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_18 PF13238.6 GBG83520.1 - 0.0029 18.1 0.0 0.0098 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG83520.1 - 0.014 15.1 0.2 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GBG83520.1 - 0.029 14.8 0.0 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 GBG83520.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.22 GBG83520.1 - 0.053 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.15 GBG83520.1 - 0.07 13.0 0.2 0.33 10.8 0.0 2.3 2 1 1 3 3 3 0 NTPase AAA_14 PF13173.6 GBG83520.1 - 0.072 13.1 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GBG83520.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GBG83520.1 - 0.081 13.2 0.7 5.6 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 GBG83520.1 - 0.09 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FA_desaturase PF00487.24 GBG83521.1 - 3.9e-36 125.2 9.2 3.9e-36 125.2 9.2 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 GBG83521.1 - 2.8e-18 65.8 0.0 6.4e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1129 PF06570.11 GBG83521.1 - 0.071 12.6 0.4 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) 7tm_3 PF00003.22 GBG83521.1 - 0.88 9.2 5.7 1.8 8.2 5.7 1.5 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF1992 PF09350.10 GBG83523.1 - 3.2e-16 59.2 0.0 9.1e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) EzrA PF06160.12 GBG83523.1 - 0.1 10.8 0.1 0.14 10.3 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Methyltransf_29 PF03141.16 GBG83524.1 - 1.8e-146 488.7 0.0 2.2e-146 488.4 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 GBG83524.1 - 2e-09 37.9 0.0 1.5e-05 25.5 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 GBG83524.1 - 1.5e-07 32.0 0.0 0.0026 18.4 0.0 2.8 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 GBG83524.1 - 1.3e-05 25.0 0.0 0.18 11.6 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 GBG83524.1 - 0.0006 19.7 0.0 0.1 12.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG83524.1 - 0.0012 19.5 0.0 0.69 10.7 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain DUF2407_C PF13373.6 GBG83525.1 - 0.67 10.1 2.4 1.9 8.7 0.6 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF4407 PF14362.6 GBG83525.1 - 5.1 6.3 5.6 14 4.9 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Integrase_H2C2 PF17921.1 GBG83526.1 - 2.5e-15 56.3 0.0 5.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG83526.1 - 0.0016 18.6 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger NOA36 PF06524.12 GBG83527.1 - 0.0092 15.3 13.3 0.0092 15.3 13.3 2.0 2 0 0 2 2 2 1 NOA36 protein SDA1 PF05285.12 GBG83527.1 - 0.64 9.4 25.1 1 8.7 21.0 2.1 2 0 0 2 2 2 0 SDA1 RNA_pol_Rpc4 PF05132.14 GBG83527.1 - 1.1 9.7 4.6 3.8 7.9 4.4 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 Mpp10 PF04006.12 GBG83527.1 - 1.4 7.3 23.1 0.73 8.2 18.4 2.0 2 0 0 2 2 2 0 Mpp10 protein THOC2_N PF16134.5 GBG83527.1 - 1.4 7.4 5.6 2.4 6.7 5.6 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Sigma70_ner PF04546.13 GBG83527.1 - 2.4 8.0 19.5 2.6 7.9 12.9 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region BUD22 PF09073.10 GBG83527.1 - 5.1 6.3 18.1 0.89 8.8 13.1 1.9 2 0 0 2 2 2 0 BUD22 PPP4R2 PF09184.11 GBG83527.1 - 6.3 6.3 20.6 0.23 11.0 13.0 2.0 2 0 0 2 2 2 0 PPP4R2 Drc1-Sld2 PF11719.8 GBG83527.1 - 7.6 6.0 11.9 3.9 6.9 6.8 2.0 2 0 0 2 2 2 0 DNA replication and checkpoint protein DDE_Tnp_4 PF13359.6 GBG83528.1 - 5.2e-28 97.7 0.0 2e-27 95.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83528.1 - 4.6e-12 46.0 0.0 7.4e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83528.1 - 0.0021 17.7 0.2 0.054 13.1 0.0 2.4 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG83528.1 - 0.038 14.3 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG83529.1 - 6.3e-08 32.9 4.3 7.6e-08 32.6 2.3 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83529.1 - 0.007 16.7 3.2 0.012 15.9 2.0 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG83529.1 - 0.27 11.5 1.9 0.92 9.8 0.7 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain SLM4 PF16818.5 GBG83530.1 - 0.1 12.6 0.0 0.11 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein SLM4 SNF2_N PF00176.23 GBG83531.1 - 7.1e-38 130.2 0.0 4.4e-37 127.6 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG83531.1 - 7.5e-17 61.7 0.0 2.1e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_34 PF13872.6 GBG83531.1 - 1.5e-05 24.0 0.1 2.8e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 ResIII PF04851.15 GBG83531.1 - 0.00021 21.4 1.4 0.00062 19.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Galactosyl_T PF01762.21 GBG83532.1 - 2e-37 129.0 1.0 7.1e-33 114.1 0.0 2.1 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 GBG83532.1 - 3.1e-05 23.5 0.1 5.2e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Fringe-like GRP PF07172.11 GBG83532.1 - 0.0017 19.0 0.9 0.0017 19.0 0.9 2.9 2 1 0 2 2 2 1 Glycine rich protein family RT_RNaseH_2 PF17919.1 GBG83533.1 - 5.4e-16 58.5 0.0 1.4e-15 57.1 0.0 1.7 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83533.1 - 1.1e-13 51.3 0.0 2.9e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83533.1 - 3.3e-06 27.3 0.0 7.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG83533.1 - 0.0096 16.0 0.4 0.0096 16.0 0.4 2.5 2 0 0 2 2 2 1 Zinc knuckle F420_oxidored PF03807.17 GBG83533.1 - 0.017 15.7 0.2 0.062 13.9 0.1 2.0 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent BUD22 PF09073.10 GBG83533.1 - 0.097 12.0 27.7 0.17 11.2 27.7 1.3 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 GBG83533.1 - 0.2 11.8 28.6 0.51 10.4 28.6 1.7 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GBG83533.1 - 0.47 9.8 27.1 0.83 9.0 27.1 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG83533.1 - 1.3 7.1 28.1 2.3 6.3 28.1 1.3 1 0 0 1 1 1 0 Nop14-like family CPSF100_C PF13299.6 GBG83533.1 - 2.5 8.3 7.8 6.7 6.9 7.8 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 GBG83533.1 - 3.6 5.8 21.1 5.8 5.1 21.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 GBG83533.1 - 5.4 6.8 13.4 15 5.3 13.4 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Afi1 PF07792.12 GBG83533.1 - 5.6 7.4 8.5 15 6.0 8.5 1.8 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RT_RNaseH_2 PF17919.1 GBG83534.1 - 1.8e-27 95.3 0.0 5e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83534.1 - 5e-24 84.6 0.0 1.2e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83534.1 - 2.7e-21 76.1 1.1 2.2e-20 73.1 0.4 2.7 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83534.1 - 2.2e-16 59.7 0.0 5.1e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG83534.1 - 3.6e-07 30.7 0.0 1.4e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83534.1 - 9.8e-07 29.3 0.0 2.7e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83534.1 - 4e-06 26.6 0.0 8.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83534.1 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease P5CR_dimer PF14748.6 GBG83535.1 - 2.5e-15 56.6 0.0 3.6e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Latarcin PF10279.9 GBG83535.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Latarcin precursor LMBR1 PF04791.16 GBG83536.1 - 0.0011 17.9 2.9 0.0017 17.3 2.9 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Protocadherin PF08374.11 GBG83536.1 - 0.27 11.2 1.9 0.52 10.2 1.9 1.4 1 0 0 1 1 1 0 Protocadherin Pinin_SDK_memA PF04696.13 GBG83536.1 - 0.31 11.1 26.7 0.91 9.6 12.4 2.6 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region WD40 PF00400.32 GBG83537.1 - 2.1e-06 28.4 0.0 0.0026 18.6 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat RVT_1 PF00078.27 GBG83537.1 - 0.018 14.6 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TFIID-18kDa PF02269.16 GBG83538.1 - 0.0083 16.1 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit XRN_M PF17846.1 GBG83538.1 - 0.19 10.6 3.7 0.26 10.2 3.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain TFIIA PF03153.13 GBG83538.1 - 7.5 6.4 17.4 8.9 6.2 17.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH_2 PF17919.1 GBG83539.1 - 3.9e-33 113.5 0.0 8e-33 112.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83539.1 - 1.3e-31 109.9 0.1 2e-31 109.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83539.1 - 1.3e-29 102.6 0.1 2.5e-29 101.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG83541.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG83542.1 - 1.7e-35 122.5 0.0 3e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG83542.1 - 8.6e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF928 PF06051.12 GBG83542.1 - 0.06 13.2 0.9 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) Asp_protease_2 PF13650.6 GBG83542.1 - 0.21 12.3 0.0 0.53 11.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG83543.1 - 3.3e-18 65.5 0.2 6.2e-18 64.7 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83543.1 - 6.6e-09 36.0 0.0 3.8e-08 33.5 0.0 2.4 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG83543.1 - 0.00032 21.3 0.0 0.00097 19.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83543.1 - 0.00054 20.5 0.0 0.0016 19.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG83543.1 - 0.0042 17.3 0.0 0.016 15.5 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG83543.1 - 0.0088 16.2 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG83544.1 - 1.3e-35 122.9 0.0 2.4e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83544.1 - 5.5e-29 100.1 0.1 5.9e-28 96.9 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83544.1 - 5.8e-28 97.3 0.1 1.9e-27 95.6 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83544.1 - 8.7e-19 67.4 0.1 1.8e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG83544.1 - 0.00077 19.6 0.0 0.0028 17.9 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG83544.1 - 0.098 12.9 0.1 0.36 11.0 0.1 2.0 1 0 0 1 1 1 0 Integrase core domain TTSSLRR PF12468.8 GBG83546.1 - 0.02 15.1 0.2 0.044 14.0 0.2 1.5 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Spa1_C PF18218.1 GBG83546.1 - 0.059 13.8 0.2 0.24 11.9 0.1 1.9 2 0 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain USP8_interact PF08941.10 GBG83547.1 - 0.0055 16.5 0.3 0.78 9.5 0.0 2.3 2 0 0 2 2 2 2 USP8 interacting USP8_interact PF08941.10 GBG83551.1 - 0.017 15.0 0.4 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 USP8 interacting RT_RNaseH_2 PF17919.1 GBG83556.1 - 4.8e-39 132.4 0.0 1.2e-25 89.4 0.0 3.1 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83556.1 - 2.1e-31 109.2 0.0 3.6e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83556.1 - 8.5e-30 103.1 0.0 6.7e-25 87.4 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Dzip-like_N PF13815.6 GBG83556.1 - 7.4e-27 93.7 1.6 7.4e-27 93.7 1.6 3.2 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal RVP_2 PF08284.11 GBG83556.1 - 6.5e-15 55.1 0.0 6e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83556.1 - 1.2e-07 32.3 0.0 5.5e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83556.1 - 0.001 19.6 0.0 0.0057 17.2 0.0 2.4 2 1 0 2 2 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG83556.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG83556.1 - 0.023 14.5 0.0 0.085 12.7 0.0 2.0 1 1 0 1 1 1 0 Aspartyl protease DUF5093 PF17011.5 GBG83556.1 - 0.59 10.4 2.8 1.8 8.8 2.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) ANXA2R PF15721.5 GBG83556.1 - 9.2 6.7 7.5 6.6 7.2 0.3 2.4 2 0 0 2 2 2 0 Annexin-2 receptor RT_RNaseH_2 PF17919.1 GBG83557.1 - 3e-25 88.2 0.0 9.2e-25 86.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83557.1 - 1.3e-24 86.5 0.0 2.6e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG83557.1 - 3e-07 31.0 0.0 6.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83557.1 - 3.4e-07 30.7 0.0 6.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83557.1 - 8.9e-06 25.5 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83557.1 - 9.8e-05 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG83557.1 - 0.01 15.7 1.5 0.027 14.4 0.2 2.2 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain DUF659 PF04937.15 GBG83559.1 - 1.6e-09 37.8 0.0 2.8e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVP_2 PF08284.11 GBG83560.1 - 3.8e-08 33.2 0.0 1.2e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83560.1 - 6.5e-06 26.7 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83560.1 - 2.8e-05 24.6 0.1 8.9e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83560.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG83561.1 - 2.3e-06 27.3 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 GBG83561.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Olduvai PF06758.13 GBG83561.1 - 0.14 12.5 2.6 0.4 11.0 2.6 1.8 1 0 0 1 1 1 0 Olduvai domain DUF4005 PF13178.6 GBG83562.1 - 0.094 13.4 0.3 0.14 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4005) EF-1_beta_acid PF10587.9 GBG83562.1 - 0.17 12.4 21.9 0.56 10.7 0.0 3.9 3 1 1 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region COG2 PF06148.11 GBG83564.1 - 0.0051 16.9 3.2 0.0051 16.9 3.2 3.5 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 RsbRD_N PF14361.6 GBG83564.1 - 0.068 13.9 0.1 0.068 13.9 0.1 2.3 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF1664 PF07889.12 GBG83564.1 - 0.8 9.8 7.4 4.3 7.4 0.8 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 GBG83564.1 - 0.95 7.3 3.7 1.4 6.7 2.7 1.6 1 1 0 1 1 1 0 Prominin Integrase_H2C2 PF17921.1 GBG83566.1 - 3.8e-13 49.3 0.4 9e-13 48.1 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG83566.1 - 5.3e-07 29.4 0.0 1.4e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG83566.1 - 6.5e-06 26.6 0.2 3.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83566.1 - 0.00076 19.3 1.2 0.0016 18.3 1.2 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG83566.1 - 0.0015 19.1 0.1 0.0067 17.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG83566.1 - 0.0022 18.3 0.0 0.0072 16.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 GBG83566.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase DUF776 PF05604.11 GBG83566.1 - 0.49 10.7 4.2 1 9.7 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF776) RT_RNaseH PF17917.1 GBG83567.1 - 2.4e-36 124.2 1.2 6.7e-29 100.3 0.0 3.5 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83567.1 - 4.9e-35 119.6 0.7 7.7e-28 96.5 0.0 3.5 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83567.1 - 5.4e-32 109.7 0.6 3.4e-17 62.3 0.1 3.0 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG83567.1 - 5.9e-28 97.5 0.0 3.4e-13 49.8 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain Asp_protease PF09668.10 GBG83567.1 - 2.5e-05 24.1 0.0 6.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83567.1 - 0.00018 22.0 0.0 0.00081 19.9 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG83567.1 - 0.00078 19.2 3.3 0.12 12.2 0.0 3.9 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG83567.1 - 0.016 15.4 0.2 9.8 6.5 0.0 3.1 2 0 0 2 2 2 0 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG83567.1 - 0.036 14.7 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DDHD PF02862.17 GBG83567.1 - 1.5 8.9 13.4 0.45 10.6 0.4 2.7 2 0 0 2 2 2 0 DDHD domain RT_RNaseH_2 PF17919.1 GBG83568.1 - 2.4e-27 94.9 0.0 9.6e-27 93.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83568.1 - 8.2e-27 94.2 0.0 1.4e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83568.1 - 8.7e-24 83.8 0.0 2e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83568.1 - 5e-17 61.8 0.2 5e-17 61.8 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG83568.1 - 1.6e-09 38.0 0.0 4.5e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG83568.1 - 0.00042 20.1 0.0 0.00093 19.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG83568.1 - 0.00065 20.2 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83568.1 - 0.00099 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG83568.1 - 0.0024 18.5 0.0 0.0053 17.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG83568.1 - 0.0079 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG83569.1 - 2.5e-05 24.4 1.0 5e-05 23.5 0.5 1.9 2 1 0 2 2 2 1 Retrotransposon gag protein Luteo_PO PF04662.13 GBG83569.1 - 0.0017 18.1 0.1 0.0029 17.3 0.1 1.3 1 0 0 1 1 1 1 Luteovirus P0 protein DUF4187 PF13821.6 GBG83569.1 - 0.0032 17.2 0.5 0.0032 17.2 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) LRRFIP PF09738.9 GBG83569.1 - 0.17 11.4 0.1 0.74 9.2 0.0 1.9 2 0 0 2 2 2 0 LRRFIP family Spectrin PF00435.21 GBG83569.1 - 0.19 12.2 2.2 5.4 7.5 0.0 3.2 3 1 0 3 3 3 0 Spectrin repeat SlyX PF04102.12 GBG83569.1 - 0.86 10.3 7.8 0.17 12.5 0.4 3.0 2 1 1 3 3 3 0 SlyX Retrotrans_gag PF03732.17 GBG83570.1 - 0.046 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein PNMA PF14893.6 GBG83570.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 PNMA Orbi_VP6 PF01516.16 GBG83570.1 - 3.4 7.1 8.5 5.4 6.5 8.5 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 rve PF00665.26 GBG83571.1 - 1.2e-10 41.6 0.1 3e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG83571.1 - 0.035 13.9 0.0 0.098 12.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG83572.1 - 0.004 17.4 0.4 0.037 14.3 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG83573.1 - 1.3e-26 92.9 0.0 4e-26 91.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83573.1 - 2.7e-26 91.5 0.0 7.4e-26 90.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83573.1 - 2.1e-08 34.1 0.0 5.8e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG83573.1 - 0.0019 17.9 0.0 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG83573.1 - 0.16 11.4 0.1 0.34 10.4 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) IclR PF01614.18 GBG83573.1 - 1.3 8.8 6.2 0.26 11.1 1.9 2.0 2 0 0 2 2 2 0 Bacterial transcriptional regulator RVP_2 PF08284.11 GBG83574.1 - 3.4e-07 30.1 0.0 9.3e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83574.1 - 5.1e-05 23.8 0.0 0.00093 19.8 0.0 2.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83574.1 - 7.5e-05 23.2 0.0 0.00073 20.0 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83574.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Trans_reg_C PF00486.28 GBG83574.1 - 0.042 13.9 0.4 0.17 12.0 0.4 2.1 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal DUF2385 PF09539.10 GBG83574.1 - 0.13 12.8 0.3 2 9.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) DUF4559 PF15112.6 GBG83574.1 - 2.2 7.9 9.5 0.76 9.4 6.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) RVT_1 PF00078.27 GBG83575.1 - 7.4e-26 91.0 0.0 1.3e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG83575.1 - 0.0017 18.6 0.1 0.18 12.1 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein SKA1 PF07160.12 GBG83576.1 - 0.76 9.6 11.9 0.83 9.5 10.3 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 CDC45 PF02724.14 GBG83576.1 - 0.99 7.6 5.8 1.4 7.1 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG83576.1 - 1.3 8.8 12.9 2.9 7.7 12.9 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG83576.1 - 3.4 6.3 7.1 4.8 5.8 7.1 1.1 1 0 0 1 1 1 0 Presenilin SoxZ PF08770.11 GBG83577.1 - 0.11 12.2 0.0 0.41 10.4 0.0 1.9 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ Antimicrobial11 PF08106.11 GBG83577.1 - 0.5 10.5 2.7 32 4.8 0.2 2.9 2 0 0 2 2 2 0 Formaecin family CDC73_N PF16050.5 GBG83577.1 - 0.7 9.2 3.3 5.3 6.3 0.8 2.2 2 0 0 2 2 2 0 Paf1 complex subunit CDC73 N-terminal RVT_1 PF00078.27 GBG83578.1 - 1.3e-25 90.2 0.1 2.4e-25 89.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83578.1 - 1.1e-13 51.1 0.6 5.7e-13 48.8 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG83578.1 - 3.1e-13 49.4 0.0 6.8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG83578.1 - 2.5e-12 47.1 0.1 1.3e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Histone_H2A_C PF16211.5 GBG83579.1 - 2.6e-19 68.6 0.8 4.4e-19 67.9 0.8 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GBG83579.1 - 6.5e-15 55.7 0.0 8.3e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG83579.1 - 4.3e-05 23.7 0.0 5.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RVT_1 PF00078.27 GBG83580.1 - 4.3e-29 101.6 0.1 7.5e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83580.1 - 8.3e-29 99.6 0.0 3.1e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83580.1 - 7.1e-28 97.0 0.0 1.4e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83580.1 - 1.5e-14 53.8 0.4 6.6e-14 51.8 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG83580.1 - 9.1e-13 48.5 0.0 3.1e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG83580.1 - 1.8e-12 47.0 0.0 3.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG83580.1 - 0.00081 19.6 0.3 0.0018 18.4 0.3 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG83581.1 - 8e-33 112.5 0.0 5.1e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83581.1 - 2.2e-31 108.2 0.0 4.6e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83581.1 - 9e-21 74.4 0.0 1.7e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 GBG83581.1 - 0.13 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like gag-asp_proteas PF13975.6 GBG83582.1 - 0.015 15.8 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG83582.1 - 0.032 14.5 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83582.1 - 0.04 14.6 0.1 0.097 13.3 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease ACT_3 PF10000.9 GBG83582.1 - 0.16 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 ACT domain Kelch_1 PF01344.25 GBG83583.1 - 7.1e-37 124.7 15.1 1.1e-09 37.8 0.3 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 GBG83583.1 - 1e-20 72.8 8.8 0.00041 20.2 0.0 6.7 5 1 1 6 6 6 4 Kelch motif Kelch_6 PF13964.6 GBG83583.1 - 3.8e-20 71.4 10.9 4.4e-06 26.8 0.1 6.2 4 1 2 6 6 6 4 Kelch motif Kelch_4 PF13418.6 GBG83583.1 - 9.1e-12 44.8 2.4 1.9e-05 24.6 0.1 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 GBG83583.1 - 1.3e-11 44.4 3.5 0.042 14.1 0.0 5.4 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG83583.1 - 6.5e-09 35.6 12.5 0.077 13.0 0.2 6.8 7 0 0 7 7 7 3 Kelch motif F-box PF00646.33 GBG83583.1 - 3.8e-06 26.6 0.1 7.3e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG83583.1 - 0.0018 18.1 0.1 0.0078 16.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like RVT_1 PF00078.27 GBG83584.1 - 2.5e-16 59.9 0.1 7.6e-16 58.3 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83584.1 - 1.5e-07 32.0 0.0 3.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83584.1 - 5.2e-07 29.5 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG83584.1 - 6.9e-05 23.3 0.0 0.00022 21.7 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease SlyX PF04102.12 GBG83584.1 - 0.0024 18.4 2.0 0.0024 18.4 2.0 2.6 3 1 0 3 3 3 1 SlyX Asp_protease PF09668.10 GBG83584.1 - 0.022 14.5 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG83585.1 - 3.1e-05 23.9 0.0 5.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ASXH PF13919.6 GBG83586.1 - 4.4e-09 36.5 0.0 8.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Asx homology domain RPN13_C PF16550.5 GBG83586.1 - 3.2e-07 30.5 0.0 6.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 UCH-binding domain SOBP PF15279.6 GBG83586.1 - 5.3 7.6 8.6 15 6.1 8.6 1.7 1 1 0 1 1 1 0 Sine oculis-binding protein DUF5553 PF17707.1 GBG83587.1 - 0.083 12.3 2.6 0.14 11.5 2.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5553) RVT_1 PF00078.27 GBG83588.1 - 3.8e-32 111.6 0.0 6.5e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83588.1 - 1.8e-31 108.1 0.0 4e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83588.1 - 1e-29 102.9 0.0 2e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GATA PF00320.27 GBG83588.1 - 1.5e-12 46.9 6.1 1.5e-12 46.9 6.1 2.2 2 0 0 2 2 2 1 GATA zinc finger RVP_2 PF08284.11 GBG83588.1 - 2.8e-06 27.1 0.0 5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83588.1 - 0.0062 17.1 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Phage_GPO PF05929.11 GBG83588.1 - 0.023 14.4 0.7 0.066 12.8 0.1 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase gag-asp_proteas PF13975.6 GBG83588.1 - 0.076 13.6 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DIOX_N PF14226.6 GBG83589.1 - 2.1e-07 31.7 0.0 3.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PRIMA1 PF16101.5 GBG83589.1 - 0.62 10.1 3.2 1.3 9.0 3.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RVT_1 PF00078.27 GBG83590.1 - 2e-08 34.0 0.0 3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VirDNA-topo-I_N PF09266.10 GBG83590.1 - 0.13 12.5 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal RT_RNaseH PF17917.1 GBG83593.1 - 1.1e-28 99.6 0.0 2.2e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83593.1 - 8.3e-28 96.4 0.0 1.7e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83593.1 - 2.8e-15 56.1 0.1 5.3e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83593.1 - 0.0077 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain CBM_20 PF00686.19 GBG83593.1 - 0.0079 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain IATP PF04568.12 GBG83595.1 - 4.8 7.7 8.6 1.3 9.5 0.1 3.3 3 1 1 4 4 4 0 Mitochondrial ATPase inhibitor, IATP RVT_1 PF00078.27 GBG83597.1 - 1.4e-29 103.3 0.0 2.1e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83597.1 - 5.7e-24 84.4 0.0 1.4e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83597.1 - 2.1e-23 82.3 0.0 5.8e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83597.1 - 5.8e-17 61.6 0.2 1.9e-16 59.9 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG83597.1 - 3e-09 37.1 0.0 8.9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG83597.1 - 0.022 14.6 0.1 0.041 13.8 0.1 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG83597.1 - 0.1 12.8 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG83598.1 - 4.2e-15 55.6 0.0 7.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83598.1 - 1.6e-07 31.1 0.0 2.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83598.1 - 0.0011 19.2 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83599.1 - 3.6e-29 101.9 0.3 9.9e-28 97.2 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG83599.1 - 4.2e-09 36.3 0.0 9.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83599.1 - 8e-09 36.0 0.0 2.5e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83599.1 - 3.1e-07 30.8 0.0 9.7e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83599.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG83599.1 - 0.0045 17.2 0.1 0.034 14.4 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein SlyX PF04102.12 GBG83599.1 - 0.0048 17.5 1.7 0.0048 17.5 1.7 2.9 4 0 0 4 4 4 1 SlyX CENP-F_leu_zip PF10473.9 GBG83599.1 - 0.18 11.8 2.9 0.34 10.9 1.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase_Tyr PF07714.17 GBG83600.1 - 1.3e-75 254.0 0.0 1.8e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83600.1 - 2.6e-60 204.0 0.0 3.8e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ACT PF01842.25 GBG83600.1 - 1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 ACT domain Pkinase_fungal PF17667.1 GBG83600.1 - 0.0012 17.8 0.1 0.0022 16.9 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GBG83600.1 - 0.0054 16.1 0.0 0.02 14.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GBG83600.1 - 0.0091 15.0 0.2 0.017 14.1 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GBG83600.1 - 0.0099 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG83600.1 - 0.042 13.8 0.1 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family PG_binding_2 PF08823.11 GBG83600.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Pkinase_Tyr PF07714.17 GBG83601.1 - 1.1e-75 254.2 0.0 1.6e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83601.1 - 2.2e-60 204.2 0.0 3.3e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ACT PF01842.25 GBG83601.1 - 9.5e-08 31.7 0.0 2.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain Pkinase_fungal PF17667.1 GBG83601.1 - 0.001 17.9 0.1 0.002 17.0 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GBG83601.1 - 0.0048 16.3 0.0 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GBG83601.1 - 0.009 15.0 0.2 0.016 14.2 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GBG83601.1 - 0.0092 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GBG83601.1 - 0.038 13.9 0.1 0.096 12.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family PG_binding_2 PF08823.11 GBG83601.1 - 0.061 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain gag-asp_proteas PF13975.6 GBG83602.1 - 6.5e-09 36.2 0.2 4.5e-05 23.9 0.1 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83602.1 - 7.5e-06 25.8 0.2 0.003 17.3 0.1 2.4 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG83602.1 - 2e-05 24.4 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83602.1 - 0.00013 22.6 0.1 0.002 18.7 0.1 2.5 2 0 0 2 2 2 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG83602.1 - 0.00026 20.6 2.3 0.13 11.9 0.2 2.6 2 0 0 2 2 2 2 Topoisomerase I zinc-ribbon-like ATE_N PF04376.13 GBG83602.1 - 0.00031 21.1 1.5 3.6 8.0 0.1 4.2 4 0 0 4 4 4 2 Arginine-tRNA-protein transferase, N terminus Hex_IIIa PF02455.16 GBG83602.1 - 0.053 12.3 0.0 6.6 5.4 0.0 2.1 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) DUF4992 PF16383.5 GBG83602.1 - 0.083 12.4 0.0 18 4.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function zf-CCHC PF00098.23 GBG83602.1 - 0.22 11.6 8.9 0.18 12.0 2.3 2.6 2 0 0 2 2 2 0 Zinc knuckle MBD PF01429.19 GBG83603.1 - 8.4e-11 41.4 0.1 1.7e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Methyl-CpG binding domain zf-CW PF07496.15 GBG83603.1 - 3.6e-08 33.3 0.8 6.1e-08 32.6 0.8 1.4 1 0 0 1 1 1 1 CW-type Zinc Finger zf-CCHC PF00098.23 GBG83606.1 - 0.00048 20.1 3.0 0.00079 19.4 3.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG83606.1 - 0.16 11.8 1.1 0.83 9.5 0.4 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG83606.1 - 0.17 11.7 0.8 0.29 10.9 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4604 PF15377.6 GBG83606.1 - 0.45 10.9 13.9 0.63 10.5 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) TAL_FSA PF00923.19 GBG83607.1 - 5.6e-50 170.3 0.0 7.1e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase WD40 PF00400.32 GBG83608.1 - 1.4e-12 47.9 7.8 0.01 16.7 0.1 5.6 6 0 0 6 6 5 3 WD domain, G-beta repeat Frtz PF11768.8 GBG83608.1 - 0.0036 15.7 1.0 0.004 15.5 0.0 1.5 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Trimer_CC PF08954.11 GBG83608.1 - 0.0044 16.6 7.5 0.036 13.6 4.9 2.5 2 0 0 2 2 2 1 Trimerisation motif DUF4407 PF14362.6 GBG83608.1 - 0.0083 15.5 0.4 0.01 15.2 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Nup160 PF11715.8 GBG83608.1 - 0.018 13.7 1.6 2.2 6.8 0.1 3.3 1 1 1 3 3 3 0 Nucleoporin Nup120/160 ATG16 PF08614.11 GBG83608.1 - 0.027 14.7 11.3 0.038 14.2 11.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Cep57_CLD PF14073.6 GBG83608.1 - 0.031 14.3 12.8 0.054 13.5 12.8 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 GAS PF13851.6 GBG83608.1 - 0.043 13.2 12.1 0.065 12.6 12.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ApoLp-III PF07464.11 GBG83608.1 - 0.078 13.1 7.4 0.12 12.4 7.4 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF713 PF05218.14 GBG83608.1 - 0.11 12.3 4.5 0.16 11.7 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Jnk-SapK_ap_N PF09744.9 GBG83608.1 - 0.11 12.7 12.9 0.19 11.9 12.9 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 GBG83608.1 - 0.16 12.5 13.8 0.23 12.0 12.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region AAA_13 PF13166.6 GBG83608.1 - 0.3 9.7 9.1 0.4 9.3 9.1 1.1 1 0 0 1 1 1 0 AAA domain WD40_alt PF14077.6 GBG83608.1 - 0.32 10.9 6.2 9.6 6.2 0.1 3.6 3 0 0 3 3 3 0 Alternative WD40 repeat motif Fib_alpha PF08702.10 GBG83608.1 - 0.36 11.0 5.1 0.69 10.1 5.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 GBG83608.1 - 0.57 10.5 8.0 0.24 11.7 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) EssA PF10661.9 GBG83608.1 - 0.79 9.6 6.7 1.3 8.9 6.7 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA TMF_DNA_bd PF12329.8 GBG83608.1 - 0.81 9.7 15.7 0.55 10.3 6.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 GBG83608.1 - 0.85 7.5 4.0 1.1 7.1 4.0 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 GBG83608.1 - 0.9 9.6 4.9 1.7 8.7 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 GBG83608.1 - 1.2 8.9 7.2 0.52 10.1 3.8 2.0 1 1 0 2 2 2 0 Septum formation initiator Atg14 PF10186.9 GBG83608.1 - 1.5 7.8 7.9 2.3 7.2 7.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lectin_N PF03954.14 GBG83608.1 - 1.6 8.5 4.3 2.9 7.6 0.9 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain FlaC_arch PF05377.11 GBG83608.1 - 1.7 9.1 8.5 0.32 11.4 3.4 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF5446 PF17522.2 GBG83608.1 - 1.8 8.8 6.1 1.1 9.5 2.7 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5446) ZapB PF06005.12 GBG83608.1 - 1.8 9.1 15.9 0.064 13.7 5.4 2.3 1 1 1 2 2 2 0 Cell division protein ZapB TMPIT PF07851.13 GBG83608.1 - 1.9 7.6 8.3 2.8 7.1 8.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein FIN1 PF17300.2 GBG83608.1 - 3.8 7.0 9.5 5.5 6.4 9.5 1.2 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 DDE_Tnp_4 PF13359.6 GBG83614.1 - 5.4e-15 55.4 0.0 1.9e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83614.1 - 1.9e-06 27.6 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Erythro_esteras PF05139.14 GBG83615.1 - 1.3e-106 357.3 2.9 1.7e-106 357.0 2.9 1.1 1 0 0 1 1 1 1 Erythromycin esterase WI12 PF07107.11 GBG83615.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Wound-induced protein WI12 Erythro_esteras PF05139.14 GBG83616.1 - 3.6e-119 398.6 3.3 4.6e-119 398.3 3.3 1.1 1 0 0 1 1 1 1 Erythromycin esterase Maf1 PF09174.10 GBG83617.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 Maf1 regulator DUF1843 PF08898.10 GBG83618.1 - 0.26 11.8 2.0 8.9 6.9 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) RT_RNaseH_2 PF17919.1 GBG83619.1 - 3.6e-14 52.6 0.0 6.8e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83619.1 - 1e-07 31.7 0.1 2.4e-05 24.0 0.1 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83619.1 - 0.00015 22.0 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83620.1 - 1.1e-31 108.8 0.0 2e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83620.1 - 1.2e-30 105.8 0.0 3.2e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83620.1 - 3.6e-07 29.9 0.1 6.1e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Topo_Zn_Ribbon PF08272.11 GBG83622.1 - 0.072 12.8 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Pkinase_Tyr PF07714.17 GBG83623.1 - 3.5e-58 196.9 0.0 3.1e-36 125.0 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG83623.1 - 1.8e-52 178.3 0.0 3.4e-33 115.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG83623.1 - 4e-29 100.6 0.0 8.7e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83623.1 - 6.2e-25 87.5 0.0 1.5e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 GBG83623.1 - 1.1e-06 29.3 15.1 0.067 14.1 0.1 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Histone PF00125.24 GBG83623.1 - 0.62 10.4 4.2 0.49 10.8 0.0 2.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Myb_DNA-bind_4 PF13837.6 GBG83626.1 - 5.7e-08 33.0 2.8 1.5e-07 31.7 2.8 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG83626.1 - 0.00068 19.7 0.7 0.0015 18.6 0.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83626.1 - 0.006 16.9 2.3 0.0073 16.6 0.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like MAP17 PF15807.5 GBG83626.1 - 0.015 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 BTB PF00651.31 GBG83627.1 - 2.6e-15 56.6 0.0 5.3e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 GBG83627.1 - 3.7e-07 30.2 0.3 7e-07 29.3 0.3 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 GBG83628.1 - 2.9e-15 56.5 0.0 5.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 GBG83628.1 - 3.7e-07 30.2 0.3 6.9e-07 29.3 0.3 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch DDE_Tnp_4 PF13359.6 GBG83629.1 - 7e-32 110.3 0.0 1.2e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83629.1 - 1.4e-13 50.9 0.0 2.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83629.1 - 2e-05 24.3 0.4 0.045 13.4 0.0 2.9 3 0 0 3 3 3 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG83630.1 - 1.2e-07 32.0 4.1 1.2e-07 32.0 4.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83630.1 - 0.001 19.3 1.2 0.0032 17.7 1.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-CCHC PF00098.23 GBG83632.1 - 0.0011 19.0 2.9 0.0011 19.0 2.9 2.4 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG83634.1 - 0.0015 19.1 0.3 0.0059 17.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG83634.1 - 0.0017 18.1 0.1 0.0034 17.1 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83634.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG83634.1 - 0.05 13.7 1.9 0.093 12.8 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle MFMR_assoc PF16596.5 GBG83634.1 - 0.11 12.9 4.5 0.26 11.8 4.5 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR Topo_Zn_Ribbon PF08272.11 GBG83634.1 - 0.12 12.0 0.2 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like SRF-TF PF00319.18 GBG83637.1 - 1.8e-26 91.3 0.1 4.3e-26 90.2 0.1 1.7 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) K-box PF01486.17 GBG83637.1 - 2.5e-08 34.0 0.6 5.5e-08 32.9 0.3 1.7 2 0 0 2 2 2 1 K-box region CENP-B_dimeris PF09026.10 GBG83637.1 - 0.18 12.2 8.3 0.38 11.2 8.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 GBG83637.1 - 0.31 10.7 2.1 0.62 9.7 2.1 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 GBG83637.1 - 0.51 9.6 9.0 0.023 14.0 3.4 1.5 2 0 0 2 2 2 0 NOA36 protein RXT2_N PF08595.11 GBG83637.1 - 3.1 7.8 5.6 6 6.9 5.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Acetyltransf_7 PF13508.7 GBG83639.1 - 3.3e-07 30.6 0.0 4.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GBG83639.1 - 2.4e-06 27.7 0.0 3.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 GBG83639.1 - 0.0044 17.7 0.0 0.0054 17.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GBG83639.1 - 0.0052 16.9 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 GBG83639.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GBG83639.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Cytochrom_B561 PF03188.16 GBG83640.1 - 0.00011 22.4 4.6 0.00011 22.4 4.6 2.2 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 DUF568 PF04526.13 GBG83640.1 - 0.0065 17.2 0.0 0.011 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF568) DUF4079 PF13301.6 GBG83640.1 - 0.018 15.2 2.9 0.018 15.2 2.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Bact_lectin PF18483.1 GBG83640.1 - 0.2 11.6 0.2 0.37 10.8 0.2 1.3 1 0 0 1 1 1 0 Bacterial lectin SdpI PF13630.6 GBG83640.1 - 0.64 10.2 16.6 4.4 7.5 4.6 4.0 4 0 0 4 4 4 0 SdpI/YhfL protein family Frag1 PF10277.9 GBG83640.1 - 0.82 9.2 6.4 0.26 10.8 1.3 2.3 2 1 0 2 2 2 0 Frag1/DRAM/Sfk1 family RVT_1 PF00078.27 GBG83641.1 - 1.1e-27 97.0 0.0 8.7e-27 94.1 0.0 2.4 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83641.1 - 1.6e-26 92.2 0.0 9.5e-26 89.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83641.1 - 5.4e-22 78.1 0.6 4.2e-21 75.2 0.0 2.8 4 0 0 4 4 4 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG83641.1 - 5.9e-10 39.7 0.0 1.7e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83641.1 - 1.1e-08 35.6 0.0 3.4e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG83641.1 - 3.2e-05 23.7 0.0 9.5e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83641.1 - 8e-05 22.4 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG83641.1 - 0.0068 16.3 0.1 0.019 14.9 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG83641.1 - 0.096 13.0 11.6 0.26 11.6 0.1 4.4 4 0 0 4 4 4 0 Retrotransposon gag protein SPACA9 PF15120.6 GBG83641.1 - 0.14 11.9 1.2 0.61 9.9 0.6 2.3 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 RVT_1 PF00078.27 GBG83642.1 - 2.9e-32 112.0 0.1 4.6e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83642.1 - 9.8e-31 105.8 0.1 1.8e-30 104.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83642.1 - 3.7e-26 91.5 0.1 6.7e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83642.1 - 8.1e-15 54.7 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain PTCB-BRCT PF12738.7 GBG83643.1 - 4.3e-47 157.9 4.8 2.1e-18 66.0 0.1 5.2 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.26 GBG83643.1 - 2.9e-35 120.5 0.1 5.5e-10 39.5 0.0 5.4 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GBG83643.1 - 7.8e-25 87.1 0.0 4.3e-05 23.9 0.0 5.5 5 0 0 5 5 5 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 GBG83643.1 - 2.6e-09 37.3 4.8 0.66 10.3 0.0 5.2 5 0 0 5 5 5 4 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 GBG83643.1 - 2.9e-09 36.9 0.7 0.73 9.9 0.1 5.2 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 GBG83643.1 - 0.00022 21.1 0.0 1.1 9.2 0.0 4.6 5 0 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 GBG83644.1 - 1.1e-29 102.1 1.3 3.5e-19 68.5 0.1 3.2 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 GBG83644.1 - 4.5e-21 75.0 0.1 8.3e-11 42.1 0.0 3.2 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GBG83644.1 - 1.2e-09 38.4 0.1 0.0023 18.3 0.0 3.1 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 GBG83644.1 - 3.2e-06 27.1 0.4 0.13 12.3 0.1 2.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain gpUL132 PF11359.8 GBG83645.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 RVT_1 PF00078.27 GBG83646.1 - 8.7e-37 126.8 0.0 1.6e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83646.1 - 2e-30 105.2 0.0 3.9e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83646.1 - 4.5e-30 103.6 0.0 1e-29 102.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83646.1 - 1.2e-19 70.2 0.3 2.7e-19 69.0 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83646.1 - 1.9e-16 60.3 0.0 7.8e-16 58.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG83646.1 - 0.00067 19.8 0.0 0.0024 18.0 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF4392 PF14336.6 GBG83646.1 - 0.054 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Phage_GPO PF05929.11 GBG83646.1 - 0.24 11.0 0.1 0.4 10.3 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SCP2 PF02036.17 GBG83649.1 - 1.1e-06 29.1 0.1 3.5e-06 27.4 0.1 1.9 2 1 1 3 3 3 1 SCP-2 sterol transfer family DTHCT PF08070.11 GBG83650.1 - 0.042 14.6 0.6 0.13 13.0 0.6 1.8 1 0 0 1 1 1 0 DTHCT (NUC029) region Myb_DNA-bind_4 PF13837.6 GBG83651.1 - 4e-09 36.7 4.2 6.4e-09 36.1 4.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG83652.1 - 2.4e-06 27.3 0.0 4.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83652.1 - 9.4e-06 25.4 0.0 5.7e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Plant transposon protein APG6_N PF17675.1 GBG83652.1 - 0.32 11.5 5.4 0.22 12.0 2.0 2.3 3 0 0 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 GBG83652.1 - 4 6.7 4.8 6.3 6.1 0.6 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Pkinase_Tyr PF07714.17 GBG83653.1 - 1.3e-37 129.6 0.0 1e-36 126.5 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG83653.1 - 6.1e-35 120.9 0.0 1.5e-34 119.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH PF17917.1 GBG83653.1 - 1.7e-26 92.5 0.8 4.4e-26 91.2 0.8 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83653.1 - 7.7e-19 67.6 0.1 2.6e-18 65.9 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83653.1 - 3.8e-18 65.4 0.2 8.2e-18 64.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83653.1 - 1.4e-14 54.3 0.0 4.4e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG83653.1 - 0.057 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein dUTPase PF00692.19 GBG83655.1 - 2.8e-44 149.9 0.0 5.4e-44 149.0 0.0 1.5 2 0 0 2 2 2 1 dUTPase LEA_2 PF03168.13 GBG83655.1 - 0.036 14.6 0.0 0.087 13.4 0.0 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein RVT_1 PF00078.27 GBG83656.1 - 1.2e-28 100.2 0.2 4.3e-28 98.4 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83656.1 - 1.3e-25 89.4 0.0 3.5e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83656.1 - 6.1e-25 87.5 0.0 1.1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83656.1 - 3.1e-20 72.0 0.2 6.6e-20 71.0 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83656.1 - 1.4e-09 38.2 0.0 3.6e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG83656.1 - 0.0012 19.0 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger MS_channel PF00924.18 GBG83659.1 - 4.3e-12 46.0 0.1 8.7e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel Formyl_trans_N PF00551.19 GBG83661.1 - 1.3e-28 99.9 0.0 2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase SDA1 PF05285.12 GBG83662.1 - 0.12 11.8 8.6 0.17 11.2 8.6 1.2 1 0 0 1 1 1 0 SDA1 DUF802 PF05650.11 GBG83662.1 - 4.2 7.9 14.0 7.7 7.1 9.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF802) DDE_Tnp_4 PF13359.6 GBG83663.1 - 1.5e-27 96.2 0.0 3.4e-27 95.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83663.1 - 1.7e-14 53.9 0.0 3.1e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83663.1 - 4.3e-06 26.5 0.1 0.15 11.7 0.0 3.2 3 0 0 3 3 3 3 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG83664.1 - 0.00017 21.9 0.4 0.0018 18.6 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG83665.1 - 1.7e-29 103.0 0.1 2.6e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG83665.1 - 3.4e-20 72.5 0.0 5.2e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83665.1 - 7e-20 71.4 0.0 8.3e-17 61.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RT_RNaseH_2 PF17919.1 GBG83665.1 - 4.4e-15 55.5 0.0 2e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83665.1 - 0.00039 20.7 0.0 0.00095 19.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TMEM154 PF15102.6 GBG83665.1 - 0.0049 16.8 2.8 0.0051 16.7 1.0 1.8 1 1 1 2 2 2 1 TMEM154 protein family DUF3377 PF11857.8 GBG83665.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4448 PF14610.6 GBG83665.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) zf-CCHC PF00098.23 GBG83667.1 - 7.1e-07 29.0 2.4 1.7e-06 27.8 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG83667.1 - 0.00071 19.3 0.7 0.00071 19.3 0.7 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG83667.1 - 0.00088 19.2 1.2 0.00088 19.2 1.2 1.8 2 0 0 2 2 2 1 Zinc knuckle DUF2058 PF09831.9 GBG83667.1 - 0.077 13.1 8.2 0.16 12.1 8.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) ArgJ PF01960.18 GBG83669.1 - 5.2e-61 206.4 1.8 3e-31 108.5 0.0 2.0 1 1 1 2 2 2 2 ArgJ family zf-CCHC PF00098.23 GBG83670.1 - 3.2e-05 23.8 1.9 0.00014 21.8 1.9 2.2 1 0 0 1 1 1 1 Zinc knuckle Peptidase_M16 PF00675.20 GBG83670.1 - 0.047 13.7 2.8 0.093 12.7 2.8 1.4 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) zf-CCHC_3 PF13917.6 GBG83670.1 - 0.076 13.0 0.8 0.24 11.4 0.8 1.9 1 0 0 1 1 1 0 Zinc knuckle Tox-ODYAM1 PF15642.6 GBG83670.1 - 0.2 10.6 8.0 0.38 9.7 8.0 1.4 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF1682 PF07946.14 GBG83670.1 - 0.72 9.0 13.8 1.5 7.9 13.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FHIPEP PF00771.20 GBG83670.1 - 5 5.5 4.4 7 5.0 4.4 1.1 1 0 0 1 1 1 0 FHIPEP family DUF1943 PF09172.11 GBG83670.1 - 9.9 5.3 6.7 16 4.6 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) ABC_membrane PF00664.23 GBG83673.1 - 2.9e-58 197.7 31.9 2.5e-29 102.8 13.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GBG83673.1 - 4.4e-51 173.0 0.0 9.6e-29 100.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 GBG83673.1 - 5.6e-08 32.9 0.9 0.001 19.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 GBG83673.1 - 6.7e-08 32.2 7.2 0.0022 17.4 0.1 4.6 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 GBG83673.1 - 1.8e-05 24.9 0.8 0.089 12.9 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 GBG83673.1 - 1.9e-05 24.6 0.5 0.13 12.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GBG83673.1 - 3.7e-05 24.2 0.2 0.42 11.0 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GBG83673.1 - 8.3e-05 22.2 0.9 0.46 10.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 GBG83673.1 - 0.00015 21.7 0.3 0.45 10.3 0.2 3.7 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 GBG83673.1 - 0.00031 20.0 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_23 PF13476.6 GBG83673.1 - 0.00048 20.7 0.1 1.1 9.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 GBG83673.1 - 0.00076 19.6 4.2 0.36 10.9 0.3 2.4 2 0 0 2 2 2 2 Dynamin family DUF1345 PF07077.11 GBG83673.1 - 0.0017 18.1 4.5 0.0021 17.8 0.3 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1345) MTABC_N PF16185.5 GBG83673.1 - 0.0038 16.8 2.6 0.015 14.8 2.6 2.0 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region T2SSE PF00437.20 GBG83673.1 - 0.012 14.7 0.0 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 GBG83673.1 - 0.038 14.3 0.3 12 6.1 0.1 3.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GBG83673.1 - 0.042 13.2 0.0 5.3 6.3 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.7 GBG83673.1 - 0.044 12.7 0.5 1.7 7.5 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain IIGP PF05049.13 GBG83673.1 - 0.055 12.5 1.1 2.2 7.3 0.1 2.5 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 GBG83673.1 - 0.11 12.0 0.2 6.5 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 GBG83673.1 - 0.19 11.5 0.7 1.5 8.5 0.2 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase Roc PF08477.13 GBG83673.1 - 0.19 12.0 1.4 19 5.5 0.1 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF4187 PF13821.6 GBG83674.1 - 0.00051 19.8 0.8 0.0015 18.3 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG83674.1 - 0.0018 18.5 2.0 0.006 16.8 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Methyltransf_8 PF05148.15 GBG83675.1 - 9.3e-76 254.5 0.0 1.9e-75 253.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Cyclin_N PF00134.23 GBG83675.1 - 1.4e-28 99.2 0.0 2.8e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GBG83675.1 - 2.1e-17 63.3 0.0 4.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Methyltransf_11 PF08241.12 GBG83675.1 - 8.9e-09 35.9 0.1 3.7e-08 33.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG83675.1 - 0.00011 22.8 0.0 0.004 17.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG83675.1 - 0.0022 17.9 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG83675.1 - 0.024 14.4 0.0 0.48 10.2 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain CbiQ PF02361.16 GBG83676.1 - 5e-27 94.9 3.5 6.8e-27 94.5 3.5 1.1 1 0 0 1 1 1 1 Cobalt transport protein zf-AN1 PF01428.16 GBG83676.1 - 5.5e-12 45.6 38.3 5.1e-07 29.7 7.6 5.1 6 0 0 6 6 6 3 AN1-like Zinc finger zf-Di19 PF05605.12 GBG83676.1 - 6.4e-05 23.2 17.4 0.064 13.6 0.1 4.3 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 GBG83676.1 - 7.7e-05 23.2 15.6 0.025 15.4 0.0 5.2 5 0 0 5 5 4 2 C2H2-type zinc finger IBR PF01485.21 GBG83676.1 - 0.0041 17.3 6.4 0.0041 17.3 6.4 3.7 4 1 0 4 4 4 1 IBR domain, a half RING-finger domain FOXP-CC PF16159.5 GBG83676.1 - 0.034 14.8 10.5 0.83 10.3 0.0 3.6 4 0 0 4 4 4 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 GBG83676.1 - 0.038 14.3 0.0 1.1 9.6 0.0 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 GBG83676.1 - 0.097 12.7 0.0 0.097 12.7 0.0 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger DUF629 PF04780.12 GBG83676.1 - 0.14 10.7 0.3 5.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 GBG83676.1 - 0.34 11.5 17.3 1.2 9.7 0.0 5.5 5 1 1 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 GBG83676.1 - 0.51 10.2 5.6 11 6.0 0.1 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Transp_Tc5_C PF04236.15 GBG83676.1 - 0.75 10.2 16.3 0.98 9.8 5.6 3.5 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain zinc_ribbon_9 PF14369.6 GBG83676.1 - 0.78 10.1 9.7 30 5.0 0.0 4.3 4 0 0 4 4 4 0 zinc-ribbon zf-AN1 PF01428.16 GBG83677.1 - 3.6e-19 68.7 35.6 3.9e-13 49.3 9.0 4.2 5 0 0 5 5 5 2 AN1-like Zinc finger zf-C2H2_4 PF13894.6 GBG83677.1 - 5.5e-07 29.9 22.8 0.0087 16.8 0.0 5.7 5 1 1 6 6 5 2 C2H2-type zinc finger zf-Di19 PF05605.12 GBG83677.1 - 1.5e-05 25.2 22.1 0.022 15.0 0.1 4.4 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 GBG83677.1 - 0.0013 18.9 6.4 0.0013 18.9 6.4 4.2 3 2 1 4 4 4 1 IBR domain, a half RING-finger domain FOXP-CC PF16159.5 GBG83677.1 - 0.0021 18.6 11.2 0.28 11.8 0.0 3.8 4 0 0 4 4 4 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 GBG83677.1 - 0.0031 17.9 22.5 0.43 11.1 0.0 6.0 5 1 1 6 6 6 2 Zinc finger, C2H2 type DUF629 PF04780.12 GBG83677.1 - 0.016 13.7 0.3 1.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Transp_Tc5_C PF04236.15 GBG83677.1 - 0.03 14.7 24.8 0.3 11.5 5.6 3.1 2 1 1 3 3 3 0 Tc5 transposase C-terminal domain zf-C2H2_6 PF13912.6 GBG83677.1 - 0.035 14.1 0.0 0.035 14.1 0.0 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 GBG83677.1 - 0.059 13.2 6.3 3.7 7.5 0.1 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_9 PF14369.6 GBG83677.1 - 0.35 11.2 13.7 11 6.4 0.0 4.7 5 0 0 5 5 4 0 zinc-ribbon zf_UBZ PF18439.1 GBG83677.1 - 3.9 7.1 15.0 26 4.5 0.1 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 GBG83677.1 - 6.1 7.5 20.9 0.79 10.3 1.0 5.8 5 1 0 5 5 5 0 Zinc-finger double domain UPF0547 PF10571.9 GBG83677.1 - 6.6 6.9 17.9 9.1 6.5 0.4 5.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 eIF-3c_N PF05470.12 GBG83679.1 - 1.7 6.8 15.6 0.43 8.8 6.3 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop53 PF07767.11 GBG83680.1 - 1.8 7.9 28.7 2.9 7.2 28.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CHD5 PF04420.14 GBG83681.1 - 0.26 11.1 3.9 0.55 10.1 3.9 1.5 1 0 0 1 1 1 0 CHD5-like protein RVT_1 PF00078.27 GBG83682.1 - 2.7e-48 164.4 0.1 9.5e-28 97.2 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG83682.1 - 1.6e-08 34.4 0.0 3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG83682.1 - 2e-05 24.7 0.3 1.4 9.2 0.0 3.6 3 0 0 3 3 3 2 Integrase core domain Asp_protease_2 PF13650.6 GBG83682.1 - 0.0018 18.9 0.0 0.0067 17.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83682.1 - 0.032 14.8 0.0 0.21 12.2 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF5095 PF17016.5 GBG83682.1 - 0.079 12.6 1.5 10 5.7 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) RT_RNaseH_2 PF17919.1 GBG83684.1 - 3.3e-30 104.1 0.0 1e-29 102.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83684.1 - 8.2e-29 100.0 0.0 2.4e-28 98.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83684.1 - 8.9e-12 45.0 0.1 1.6e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83684.1 - 0.00062 19.8 0.0 0.0018 18.4 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC_3 PF13917.6 GBG83685.1 - 0.0061 16.5 1.5 0.017 15.1 1.5 1.8 1 0 0 1 1 1 1 Zinc knuckle DivIC PF04977.15 GBG83685.1 - 0.67 9.8 2.8 1.2 9.0 1.5 2.1 2 0 0 2 2 2 0 Septum formation initiator zf-CCHC PF00098.23 GBG83685.1 - 0.86 9.8 4.9 1.4 9.1 4.9 1.4 1 0 0 1 1 1 0 Zinc knuckle HAUS6_N PF14661.6 GBG83685.1 - 7 6.2 8.6 0.18 11.4 0.3 2.3 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus Borrelia_P83 PF05262.11 GBG83687.1 - 3 6.2 10.1 4.5 5.6 10.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein FUSC PF04632.12 GBG83687.1 - 3.4 6.1 5.3 5.4 5.4 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PHD_Oberon PF07227.11 GBG83688.1 - 5.7e-06 26.2 7.6 1.4e-05 25.0 7.6 1.7 1 1 0 1 1 1 1 PHD - plant homeodomain finger protein PHD PF00628.29 GBG83688.1 - 0.00012 21.8 6.3 0.00012 21.8 6.3 2.4 2 0 0 2 2 2 1 PHD-finger SAP30_Sin3_bdg PF13867.6 GBG83688.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zinc-ribbons_6 PF07191.12 GBG83688.1 - 0.82 9.7 11.8 1 9.4 4.3 2.6 2 1 0 2 2 2 0 zinc-ribbons zf-RING-like PF08746.11 GBG83688.1 - 0.86 10.0 17.5 0.79 10.1 3.2 3.3 3 0 0 3 3 3 0 RING-like domain zf-C3HC4_3 PF13920.6 GBG83688.1 - 2 8.4 10.8 0.65 9.9 1.5 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 GBG83688.1 - 2.2 8.6 11.8 1.3 9.3 8.0 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain Ecm29 PF13001.7 GBG83689.1 - 3.8e-110 368.9 5.6 2.2e-92 310.4 0.0 4.5 4 1 1 5 5 5 2 Proteasome stabiliser HEAT_EZ PF13513.6 GBG83689.1 - 0.00014 22.3 7.2 4.8 7.8 0.0 6.9 7 0 0 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 GBG83689.1 - 0.0002 21.7 19.4 0.43 11.0 0.0 9.2 9 3 2 11 11 11 1 HEAT repeats Vac14_Fab1_bd PF12755.7 GBG83689.1 - 0.00043 20.8 0.1 6.4 7.4 0.0 5.3 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GBG83689.1 - 0.0011 19.0 2.9 12 6.5 0.0 6.8 8 0 0 8 8 8 1 HEAT repeat Adaptin_N PF01602.20 GBG83689.1 - 0.032 12.8 0.8 2.4 6.6 0.0 3.3 5 0 0 5 5 5 0 Adaptin N terminal region Cnd1 PF12717.7 GBG83689.1 - 0.13 12.3 4.1 14 5.7 0.0 4.7 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Nucleotid_trans PF03407.16 GBG83690.1 - 8.4e-29 101.1 0.0 1.1e-28 100.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase RT_RNaseH_2 PF17919.1 GBG83691.1 - 3.1e-30 104.2 0.0 5.5e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83691.1 - 2.9e-29 101.4 0.0 5e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83691.1 - 2.2e-06 27.4 0.1 3.2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG83693.1 - 1.3e-26 93.6 0.0 5.3e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG83693.1 - 0.046 14.3 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83693.1 - 0.15 12.7 0.0 0.43 11.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF4139 PF13598.6 GBG83694.1 - 0.0074 16.0 1.1 0.0099 15.6 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) Fzo_mitofusin PF04799.13 GBG83694.1 - 0.093 12.3 2.2 0.13 11.8 2.2 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF2866 PF11065.8 GBG83694.1 - 0.15 12.1 0.2 0.36 10.9 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2866) RVT_1 PF00078.27 GBG83695.1 - 8.6e-28 97.4 0.0 2.2e-27 96.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83695.1 - 8.6e-26 89.9 0.0 1.8e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83695.1 - 9.8e-24 83.7 0.0 2.6e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NPV_P10 PF05531.12 GBG83695.1 - 0.18 12.3 0.8 1.2 9.7 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GBG83695.1 - 2.4 7.4 12.2 5.9 6.1 5.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 GBG83695.1 - 3.2 8.4 13.3 0.027 15.1 2.6 2.9 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-CCHC_6 PF15288.6 GBG83696.1 - 0.033 14.0 0.5 0.064 13.1 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG83696.1 - 0.052 13.3 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG83696.1 - 0.083 13.0 4.1 0.13 12.4 4.1 1.3 1 0 0 1 1 1 0 Zinc knuckle BAF250_C PF12031.8 GBG83696.1 - 0.092 12.0 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Peptidase_S64 PF08192.11 GBG83696.1 - 0.13 10.7 3.1 0.17 10.3 3.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 MnmE_helical PF12631.7 GBG83696.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.2 1 1 1 2 2 2 0 MnmE helical domain HHH_9 PF17674.1 GBG83696.1 - 0.22 12.5 3.4 20 6.2 1.5 2.7 1 1 1 2 2 2 0 HHH domain zf-CCHC PF00098.23 GBG83697.1 - 0.0046 17.0 0.2 0.0073 16.3 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG83697.1 - 0.079 12.7 1.8 0.12 12.1 0.4 1.9 2 0 0 2 2 2 0 Zinc knuckle RVP_2 PF08284.11 GBG83698.1 - 9.7e-08 31.9 0.1 1.7e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG83698.1 - 0.021 15.4 0.0 0.064 13.8 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease MMR_HSR1 PF01926.23 GBG83698.1 - 0.027 14.6 0.0 0.11 12.5 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase Asp_protease_2 PF13650.6 GBG83698.1 - 0.09 13.4 0.0 0.24 12.1 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease ABC_tran PF00005.27 GBG83698.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MVL PF12151.8 GBG83698.1 - 0.11 12.3 6.5 0.099 12.5 2.4 2.5 2 0 0 2 2 2 0 Mannan-binding protein RVT_1 PF00078.27 GBG83699.1 - 1.2e-24 87.1 0.1 2.5e-24 86.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83699.1 - 4.6e-13 49.0 0.0 1.3e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG83699.1 - 5.2e-05 23.4 0.4 0.00047 20.4 0.1 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG83699.1 - 0.00025 21.3 0.0 0.00092 19.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2046 PF09755.9 GBG83699.1 - 0.16 11.2 0.6 9.8 5.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF4407 PF14362.6 GBG83700.1 - 0.074 12.4 6.6 0.076 12.4 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 GBG83700.1 - 1.2 9.5 11.7 2.1 8.7 11.7 1.3 1 0 0 1 1 1 0 YlqD protein HAUS6_N PF14661.6 GBG83700.1 - 2.1 7.9 8.1 2.6 7.6 8.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Miga PF10265.9 GBG83700.1 - 4.2 6.2 8.8 5.2 5.9 8.8 1.0 1 0 0 1 1 1 0 Mitoguardin RVT_1 PF00078.27 GBG83701.1 - 6.2e-29 101.1 0.1 1.1e-28 100.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG83701.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83701.1 - 0.00012 22.7 0.0 0.00038 21.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83701.1 - 0.0022 18.5 0.0 0.0075 16.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG83701.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Na_Ca_ex PF01699.24 GBG83704.1 - 3.8e-46 156.8 45.0 4.9e-25 88.3 15.7 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein MotB_plug PF13677.6 GBG83704.1 - 0.2 11.3 1.9 0.58 9.8 1.9 1.8 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB CCDC85 PF10226.9 GBG83705.1 - 0.0059 16.3 0.6 0.012 15.3 0.2 1.7 2 0 0 2 2 2 1 CCDC85 family CCD48 PF15799.5 GBG83705.1 - 0.01 14.2 2.6 0.016 13.6 2.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF2385 PF09539.10 GBG83705.1 - 0.018 15.5 0.1 0.71 10.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) bZIP_1 PF00170.21 GBG83705.1 - 0.072 13.2 0.6 0.23 11.6 0.6 1.9 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.18 GBG83705.1 - 0.1 12.9 2.7 0.27 11.5 2.7 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 GBG83705.1 - 0.69 10.0 7.7 0.11 12.6 3.0 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 GBG83705.1 - 1.6 8.5 4.2 0.42 10.4 0.6 1.9 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 GBG83705.1 - 7.8 7.0 7.9 0.45 11.0 1.0 2.4 3 0 0 3 3 3 0 Cell division protein ZapB RVT_1 PF00078.27 GBG83706.1 - 1.1e-20 74.1 0.0 1.7e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83706.1 - 0.0001 22.2 0.1 0.00052 20.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RNA_pol_Rpc4 PF05132.14 GBG83708.1 - 0.83 10.1 3.2 1.5 9.3 3.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 PTPRCAP PF15713.5 GBG83708.1 - 4.2 7.7 25.2 7.4 6.9 25.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Hid1 PF12722.7 GBG83708.1 - 7.9 4.5 7.1 11 4.0 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPI_Ypi1 PF07491.11 GBG83709.1 - 0.034 14.0 1.6 0.57 10.1 0.1 2.5 2 0 0 2 2 2 0 Protein phosphatase inhibitor RT_RNaseH_2 PF17919.1 GBG83710.1 - 8e-22 77.2 0.0 2.4e-21 75.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83710.1 - 9.5e-19 67.6 0.0 6.7e-18 64.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83710.1 - 6e-09 35.7 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG83710.1 - 0.00068 19.9 0.1 0.026 14.8 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein Spc29 PF17082.5 GBG83710.1 - 0.015 15.2 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 Baculo_PEP_C PF04513.12 GBG83710.1 - 0.079 13.0 1.8 0.25 11.4 0.2 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 GBG83710.1 - 0.14 11.4 0.4 1.2 8.3 0.0 2.4 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DDRGK PF09756.9 GBG83710.1 - 1.3 8.6 7.8 2.6 7.6 7.8 1.4 1 0 0 1 1 1 0 DDRGK domain Plavaka PF18759.1 GBG83711.1 - 4.8e-18 65.5 0.2 9.2e-18 64.5 0.2 1.4 1 0 0 1 1 1 1 Plavaka transposase TFIIA PF03153.13 GBG83711.1 - 0.053 13.5 11.3 0.17 11.9 11.6 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 GBG83711.1 - 5.3 5.5 10.1 7.4 5.0 10.1 1.3 1 0 0 1 1 1 0 Macoilin family DDE_Tnp_4 PF13359.6 GBG83714.1 - 1.2e-05 25.0 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83714.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG83715.1 - 0.0017 18.7 1.6 0.0017 18.7 1.6 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 GBG83716.1 - 0.061 13.6 0.1 0.19 12.0 0.1 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein DUF659 PF04937.15 GBG83717.1 - 0.00028 20.8 0.0 0.0004 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Trypsin PF00089.26 GBG83719.1 - 4.7e-42 144.3 0.0 6.6e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 GBG83719.1 - 0.18 12.2 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) DUF5069 PF16798.5 GBG83720.1 - 1.2 9.4 4.8 0.35 11.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) zf-CCHC PF00098.23 GBG83721.1 - 1e-06 28.6 2.3 2e-06 27.6 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Hamartin PF04388.12 GBG83721.1 - 0.00065 18.5 6.5 0.00074 18.3 6.5 1.1 1 0 0 1 1 1 1 Hamartin protein PA26 PF04636.13 GBG83721.1 - 0.81 8.5 5.7 1.1 8.1 5.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 GBG83721.1 - 1.5 7.5 6.6 2 7.1 6.6 1.1 1 0 0 1 1 1 0 Presenilin HSP70 PF00012.20 GBG83721.1 - 2.2 6.3 12.7 3.6 5.7 12.7 1.2 1 0 0 1 1 1 0 Hsp70 protein VIR_N PF15912.5 GBG83721.1 - 4.1 6.9 13.3 7 6.2 13.3 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Sec20 PF03908.13 GBG83722.1 - 2.3e-20 72.3 0.5 2.3e-20 72.3 0.5 2.1 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.6 GBG83722.1 - 0.024 14.0 10.2 0.032 13.6 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GBG83722.1 - 0.22 11.1 4.3 0.31 10.6 4.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3072 PF11272.8 GBG83722.1 - 0.61 10.0 3.3 0.38 10.7 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3072) Spc7 PF08317.11 GBG83722.1 - 1.8 7.4 13.1 2.7 6.8 13.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 GBG83722.1 - 2.7 8.6 9.0 19 5.9 3.9 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal LemA PF04011.12 GBG83722.1 - 5.6 6.8 8.3 1.1 9.2 3.1 2.2 1 1 0 2 2 2 0 LemA family H_PPase PF03030.16 GBG83723.1 - 8.9e-249 827.5 37.2 1.3e-248 827.0 37.2 1.2 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Gp_dh_C PF02800.20 GBG83723.1 - 9e-65 217.1 0.1 1.5e-64 216.3 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG83723.1 - 2e-28 98.7 0.0 4.8e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CP12 PF02672.15 GBG83723.1 - 4.4e-05 24.2 0.0 8.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 CP12 domain Glyco_trans_4_4 PF13579.6 GBG83724.1 - 2.4e-11 44.3 1.2 6.3e-11 43.0 1.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GBG83724.1 - 7.2e-10 39.1 0.7 1.4e-09 38.2 0.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GBG83724.1 - 1.1e-09 38.8 0.0 2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GBG83724.1 - 5e-09 35.9 0.0 1.3e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG83724.1 - 0.023 15.1 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 OST3_OST6 PF04756.13 GBG83725.1 - 6.6e-11 42.1 0.1 8.3e-11 41.8 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family NmrA PF05368.13 GBG83726.1 - 3e-29 102.3 0.0 5.4e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GBG83726.1 - 1.1e-22 80.9 0.0 2e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GBG83726.1 - 5.4e-10 39.2 0.0 9.8e-09 35.0 0.0 2.4 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GBG83726.1 - 1.8e-06 27.2 0.0 3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 GBG83726.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 GBG83726.1 - 0.023 13.8 0.0 0.065 12.4 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein TrkA_N PF02254.18 GBG83726.1 - 0.039 14.2 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 GBG83726.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 GBG83726.1 - 0.078 12.9 0.3 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 KR domain Trypsin_2 PF13365.6 GBG83727.1 - 3.6e-31 109.1 0.1 8.6e-31 107.9 0.1 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GBG83727.1 - 2e-15 57.2 0.0 3.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 GBG83727.1 - 1.2e-10 41.6 0.0 2.2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GBG83727.1 - 9.3e-07 28.6 5.8 9.2e-06 25.4 0.3 2.8 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 GBG83727.1 - 2.2e-05 24.3 0.1 4.9e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ PF00595.24 GBG83727.1 - 0.0014 19.0 0.5 0.0057 17.0 0.2 2.2 2 0 0 2 2 2 1 PDZ domain Peptidase_S29 PF02907.15 GBG83727.1 - 0.0028 17.4 0.1 0.0067 16.2 0.1 1.6 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Gp37 PF09646.10 GBG83727.1 - 0.03 14.1 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Gp37 protein EII-Sor PF03609.14 GBG83727.1 - 0.041 13.3 1.9 0.068 12.6 1.9 1.3 1 0 0 1 1 1 0 PTS system sorbose-specific iic component Peptidase_S46 PF10459.9 GBG83727.1 - 0.041 12.5 0.2 0.084 11.5 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 Connexin PF00029.19 GBG83728.1 - 0.034 13.9 1.5 0.044 13.6 1.5 1.1 1 0 0 1 1 1 0 Connexin TERB2 PF15101.6 GBG83728.1 - 0.08 13.0 1.2 0.1 12.6 1.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PBP1_TM PF14812.6 GBG83728.1 - 0.15 12.5 12.7 0.35 11.2 12.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RR_TM4-6 PF06459.12 GBG83728.1 - 0.46 10.3 7.3 0.49 10.2 7.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GBG83728.1 - 0.49 8.6 9.6 0.54 8.5 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 GBG83728.1 - 1.6 8.4 6.2 2.4 7.8 6.2 1.4 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 GBG83728.1 - 3.4 6.3 3.3 3.2 6.4 3.3 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 GBG83728.1 - 5.9 5.6 5.4 6.3 5.5 5.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ank_4 PF13637.6 GBG83729.1 - 9.1e-23 80.3 0.6 2.9e-08 34.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GBG83729.1 - 1.3e-20 73.8 1.4 1.4e-19 70.4 1.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GBG83729.1 - 3.2e-19 68.7 0.7 2.4e-10 40.5 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) STI1 PF17830.1 GBG83729.1 - 1.1e-17 63.7 13.3 4.8e-10 39.2 0.0 4.5 2 1 2 4 4 4 4 STI1 domain Ank PF00023.30 GBG83729.1 - 4e-15 55.5 0.3 1.1e-05 25.7 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 GBG83729.1 - 2.2e-13 49.1 0.0 0.0011 19.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat GerD PF17898.1 GBG83729.1 - 0.0012 18.7 7.7 0.16 11.9 0.3 2.9 2 1 0 2 2 2 2 Spore germination GerD central core domain MTS PF05175.14 GBG83729.1 - 0.11 12.0 0.2 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF1843 PF08898.10 GBG83729.1 - 0.14 12.7 1.9 0.32 11.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) RPN13_C PF16550.5 GBG83729.1 - 0.17 12.1 1.0 0.97 9.6 1.0 2.3 1 1 0 1 1 1 0 UCH-binding domain MMR_HSR1 PF01926.23 GBG83730.1 - 4.3e-08 33.2 0.0 7.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG83730.1 - 3.1e-07 30.4 0.1 6.4e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 GBG83730.1 - 0.00051 20.6 0.1 0.0012 19.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GBG83730.1 - 0.00065 20.2 0.2 0.0013 19.2 0.2 1.4 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 GBG83730.1 - 0.0033 17.5 0.2 0.023 14.8 0.2 2.0 1 1 1 2 2 2 1 Dynamin family TsaE PF02367.17 GBG83730.1 - 0.0036 17.3 0.1 0.0076 16.3 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GBG83730.1 - 0.0047 17.3 0.6 0.018 15.4 0.3 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG83730.1 - 0.0071 16.6 0.2 0.043 14.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GBG83730.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG83730.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 GBG83730.1 - 0.026 14.4 0.1 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 GBG83730.1 - 0.026 13.6 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 GBG83730.1 - 0.036 14.5 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 GBG83730.1 - 0.047 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 GBG83730.1 - 0.051 13.3 0.1 0.093 12.5 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 GBG83730.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Arf PF00025.21 GBG83730.1 - 0.071 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Sigma54_activat PF00158.26 GBG83730.1 - 0.072 12.8 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 GBG83730.1 - 0.088 12.5 0.5 0.17 11.6 0.5 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 GBG83730.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Kinesin PF00225.23 GBG83730.1 - 0.11 11.5 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Kinesin motor domain HLH PF00010.26 GBG83731.1 - 7.8e-13 48.2 0.6 1.4e-12 47.3 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CAMP_factor PF07373.11 GBG83731.1 - 0.077 12.6 0.1 0.077 12.6 0.1 1.7 2 0 0 2 2 2 0 CAMP factor (Cfa) NINJA_B PF16136.5 GBG83731.1 - 0.96 9.8 5.5 2.3 8.6 2.7 2.9 2 0 0 2 2 2 0 Putative nuclear localisation signal IncD PF17628.2 GBG83732.1 - 0.048 13.4 1.9 0.11 12.2 1.9 1.6 1 1 0 1 1 1 0 Inclusion membrane protein D DNA_pol_phi PF04931.13 GBG83733.1 - 0.37 8.8 4.8 0.46 8.5 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GBG83733.1 - 0.47 9.7 3.0 0.66 9.2 3.0 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GBG83733.1 - 0.52 10.7 11.4 1.3 9.4 11.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 GBG83733.1 - 2.5 7.8 9.0 0.52 10.0 5.5 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 GBG83733.1 - 5.4 6.9 10.0 0.85 9.5 2.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IFT81_CH PF18383.1 GBG83735.1 - 1.3e-34 119.1 0.1 1.3e-34 119.1 0.1 3.3 3 1 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain Seryl_tRNA_N PF02403.22 GBG83735.1 - 0.0076 16.5 3.5 0.0076 16.5 3.5 6.0 5 2 1 6 6 6 3 Seryl-tRNA synthetase N-terminal domain Rx_N PF18052.1 GBG83735.1 - 0.14 12.4 0.2 0.14 12.4 0.2 4.9 5 0 0 5 5 5 0 Rx N-terminal domain WD40 PF00400.32 GBG83736.1 - 4.6e-20 71.6 10.3 0.00041 21.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat CHCH PF06747.13 GBG83736.1 - 1e-07 31.9 3.4 1.8e-07 31.1 3.4 1.4 1 0 0 1 1 1 1 CHCH domain ANAPC4_WD40 PF12894.7 GBG83736.1 - 2.1e-07 31.1 0.1 1.5 9.1 0.0 4.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain MTCP1 PF08991.10 GBG83736.1 - 0.00075 19.7 3.8 0.00086 19.5 1.9 1.9 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type CX9C PF16860.5 GBG83736.1 - 0.0029 17.6 2.5 0.0055 16.7 2.5 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, WD40_like PF17005.5 GBG83736.1 - 0.021 14.2 0.1 0.089 12.1 0.1 1.9 1 1 1 2 2 2 0 WD40-like domain Rtf2 PF04641.12 GBG83737.1 - 1.7e-42 145.6 2.4 3.1e-20 72.6 0.1 3.0 1 1 2 3 3 3 2 Rtf2 RING-finger Prok-RING_4 PF14447.6 GBG83737.1 - 0.037 13.9 0.0 0.098 12.5 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PIP49_C PF12260.8 GBG83737.1 - 5.2 6.7 8.1 2.1 7.9 4.7 2.0 2 1 0 2 2 2 0 Protein-kinase domain of FAM69 MRP-L46 PF11788.8 GBG83738.1 - 0.0012 19.6 0.1 0.0035 18.1 0.1 1.7 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 GBG83738.1 - 0.041 13.9 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 NUDIX domain Copine PF07002.16 GBG83739.1 - 5.4e-67 225.4 0.0 8.6e-67 224.8 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GBG83739.1 - 1.4e-31 108.8 0.0 1.3e-15 57.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GBG83739.1 - 0.067 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus RVT_1 PF00078.27 GBG83741.1 - 2.1e-32 112.5 0.1 3.4e-32 111.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83741.1 - 7.5e-28 96.5 0.0 4.5e-27 94.0 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83741.1 - 2.8e-19 69.3 0.0 1.6e-18 66.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF3138 PF11336.8 GBG83741.1 - 0.52 8.9 3.4 0.84 8.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) gag-asp_proteas PF13975.6 GBG83742.1 - 0.0008 19.9 0.0 0.002 18.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83742.1 - 0.0055 17.3 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG83742.1 - 0.014 15.2 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG83742.1 - 0.032 14.6 0.1 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG83743.1 - 5.5e-36 124.2 0.1 1.2e-35 123.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83743.1 - 3.3e-29 100.9 0.0 7.7e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83743.1 - 6.3e-26 90.7 0.0 1.2e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83743.1 - 2e-18 66.2 1.7 4.6e-18 65.1 1.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83743.1 - 4.7e-17 62.3 0.0 1.1e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Actin PF00022.19 GBG83743.1 - 9.8e-17 60.6 0.0 6.5e-11 41.5 0.0 3.1 3 0 0 3 3 3 2 Actin Actin_micro PF17003.5 GBG83743.1 - 5.9e-07 29.0 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Putative actin-like family RVP_2 PF08284.11 GBG83743.1 - 1e-05 25.3 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83743.1 - 0.00014 22.5 0.0 0.00043 20.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83743.1 - 0.003 18.1 0.0 0.0094 16.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG83743.1 - 0.0057 16.8 0.4 0.021 15.0 0.4 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG83743.1 - 0.015 15.1 0.0 0.036 13.8 0.0 1.6 1 1 0 1 1 1 0 Putative peptidase (DUF1758) BNIP2 PF12496.8 GBG83743.1 - 0.034 14.6 0.6 0.09 13.2 0.6 1.7 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF2862 PF11061.8 GBG83743.1 - 0.1 12.5 0.0 0.51 10.2 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) Arena_nucleocap PF00843.17 GBG83743.1 - 0.55 9.1 1.7 0.98 8.3 1.7 1.3 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain DUF4079 PF13301.6 GBG83744.1 - 5.1e-51 172.5 0.2 6.1e-51 172.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) SURF1 PF02104.15 GBG83744.1 - 0.034 14.4 0.0 0.039 14.2 0.0 1.1 1 0 0 1 1 1 0 SURF1 family DUF2681 PF10883.8 GBG83744.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) tRNA-synt_2 PF00152.20 GBG83745.1 - 8.4e-83 278.0 0.0 1.4e-82 277.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GBG83745.1 - 4.3e-12 45.8 0.0 6.6e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GBG83745.1 - 8.2e-07 28.8 0.2 0.023 14.2 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) FAD-oxidase_C PF02913.19 GBG83745.1 - 0.11 12.2 0.3 0.2 11.2 0.3 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain K_channel_TID PF07941.11 GBG83745.1 - 2.5 8.6 6.0 1 9.8 3.4 1.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain gag-asp_proteas PF13975.6 GBG83746.1 - 2.3e-10 40.9 0.0 5.9e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83746.1 - 8.9e-08 32.7 0.1 2.2e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG83746.1 - 0.0047 17.2 0.0 0.014 15.7 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG83746.1 - 0.019 15.2 0.6 0.086 13.1 0.1 2.5 3 0 0 3 3 3 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG83746.1 - 0.036 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Pep_deformylase PF01327.21 GBG83746.1 - 0.15 11.7 1.5 0.34 10.5 1.5 1.5 1 0 0 1 1 1 0 Polypeptide deformylase DUF1482 PF07358.11 GBG83747.1 - 0.16 11.9 0.1 30 4.6 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1482) UPF0051 PF01458.17 GBG83748.1 - 8.9e-67 225.0 0.1 1.2e-66 224.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) CHIPS PF11434.8 GBG83748.1 - 0.055 13.3 0.0 0.74 9.7 0.0 2.5 2 0 0 2 2 2 0 Chemotaxis-inhibiting protein CHIPS RVT_1 PF00078.27 GBG83749.1 - 8.2e-06 25.5 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prominin PF05478.11 GBG83749.1 - 0.067 11.2 1.9 0.1 10.5 1.9 1.2 1 0 0 1 1 1 0 Prominin Anticodon_1 PF08264.13 GBG83749.1 - 0.16 11.9 0.5 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA DivIC PF04977.15 GBG83749.1 - 0.23 11.3 2.6 1.1 9.1 2.6 2.2 1 0 0 1 1 1 0 Septum formation initiator 60KD_IMP PF02096.20 GBG83749.1 - 3.4 7.5 4.3 7.8 6.4 4.3 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein COMP PF11598.8 GBG83749.1 - 6.1 7.4 7.2 15 6.1 7.2 1.6 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein PsbX PF06596.11 GBG83752.1 - 4.4e-09 36.2 2.2 4.4e-09 36.2 2.2 2.3 2 0 0 2 2 2 1 Photosystem II reaction centre X protein (PsbX) Phospholamban PF04272.14 GBG83752.1 - 0.02 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Phospholamban RT_RNaseH_2 PF17919.1 GBG83753.1 - 1.1e-31 108.8 0.0 2.2e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83753.1 - 1.5e-29 102.3 0.0 2.7e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83753.1 - 1.3e-08 34.6 0.0 2.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG83753.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Myb_DNA-binding PF00249.31 GBG83755.1 - 1.1e-09 38.3 0.0 1.1e-09 38.3 0.0 2.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG83755.1 - 4.2e-05 23.7 0.2 7.7e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Suf PF05843.14 GBG83755.1 - 1.3 9.0 5.8 3 7.8 5.8 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GIY-YIG PF01541.24 GBG83758.1 - 6.2e-08 32.8 0.8 4.4e-07 30.1 0.0 2.6 2 0 0 2 2 2 1 GIY-YIG catalytic domain Peptidase_C48 PF02902.19 GBG83759.1 - 1.7e-24 86.9 0.0 2.8e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain NOA36 PF06524.12 GBG83762.1 - 0.63 9.3 29.1 0.7 9.2 29.1 1.0 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 GBG83762.1 - 2.3 8.0 8.3 2.4 8.0 8.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.11 GBG83762.1 - 4.5 7.3 13.0 5.5 7.0 13.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2722 PF10846.8 GBG83762.1 - 6.3 5.6 6.2 6.2 5.6 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) zf-UDP PF14569.6 GBG83763.1 - 0.15 12.2 0.2 0.15 12.2 0.2 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger RVT_1 PF00078.27 GBG83764.1 - 1.9e-28 99.5 0.0 3.6e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83764.1 - 3.6e-16 59.0 0.0 8.1e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83764.1 - 8.9e-05 22.7 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG83764.1 - 0.019 15.5 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83764.1 - 0.026 15.1 0.0 0.057 14.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG83764.1 - 0.084 13.2 0.0 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease DDE_Tnp_4 PF13359.6 GBG83765.1 - 2.8e-23 82.3 0.0 4.5e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83765.1 - 9e-13 48.3 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG83766.1 - 1.8e-06 28.3 3.3 4.7e-06 26.9 3.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83766.1 - 0.00038 20.7 0.9 0.0009 19.5 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG83766.1 - 0.023 14.8 1.2 0.057 13.5 1.2 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain LapA_dom PF06305.11 GBG83766.1 - 0.11 12.3 0.3 0.28 11.0 0.3 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GST_N_3 PF13417.6 GBG83767.1 - 8.1e-29 99.9 0.0 3.2e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG83767.1 - 3.7e-10 40.0 0.0 0.00022 21.4 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GBG83767.1 - 3.2e-05 24.2 0.0 0.0025 18.1 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GBG83767.1 - 0.028 14.6 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin AF-4 PF05110.13 GBG83767.1 - 2.1 6.3 13.8 2.7 6.0 13.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GATA PF00320.27 GBG83770.1 - 2.5e-15 55.8 2.7 7.1e-15 54.3 2.7 1.9 1 0 0 1 1 1 1 GATA zinc finger eIF3g PF12353.8 GBG83771.1 - 0.065 13.6 0.2 0.57 10.6 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G potato_inhibit PF00280.18 GBG83772.1 - 2.3e-22 79.4 0.5 3.1e-22 79.0 0.5 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Retrotrans_gag PF03732.17 GBG83773.1 - 0.0014 18.9 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Gln-synt_C PF00120.24 GBG83774.1 - 4.5e-48 164.0 0.0 6.7e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 GBG83774.1 - 1.2e-13 51.6 0.0 4.9e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Gln-synt_N_2 PF16952.5 GBG83774.1 - 0.00042 20.1 0.0 0.0011 18.7 0.0 1.9 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain RVT_1 PF00078.27 GBG83775.1 - 1.3e-05 24.8 0.0 0.031 13.8 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG83776.1 - 0.00042 19.9 0.0 0.017 14.7 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF67_u1 PF16615.5 GBG83777.1 - 3.5 8.2 8.4 1.1 9.8 4.9 2.0 2 0 0 2 2 2 0 Unstructured region one on RhoGEF 6 and 7 RVT_1 PF00078.27 GBG83778.1 - 5.5e-34 117.6 0.7 9.9e-34 116.8 0.2 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83778.1 - 1.5e-29 101.9 0.0 1.5e-28 98.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83778.1 - 3e-29 101.4 0.2 5e-28 97.5 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83778.1 - 1.5e-18 66.6 0.4 3.8e-18 65.3 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83778.1 - 2.6e-16 59.9 0.0 9.6e-16 58.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG83778.1 - 0.0058 16.8 0.1 0.019 15.2 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger FAM60A PF15396.6 GBG83778.1 - 0.022 14.8 3.9 0.055 13.5 3.9 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Rotamase PF00639.21 GBG83778.1 - 0.96 10.5 9.8 10 7.1 0.0 3.7 3 0 0 3 3 3 0 PPIC-type PPIASE domain TadF PF16964.5 GBG83778.1 - 1.2 8.8 4.1 3.1 7.5 4.1 1.6 1 0 0 1 1 1 0 Putative tight adherence pilin protein F LcrG PF07216.12 GBG83778.1 - 4.2 7.3 10.3 0.34 10.9 0.4 2.7 2 0 0 2 2 2 0 LcrG protein Peptidase_S64 PF08192.11 GBG83778.1 - 8.8 4.7 10.1 14 4.0 10.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 RVT_1 PF00078.27 GBG83779.1 - 0.0025 17.3 0.0 0.0057 16.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG83779.1 - 0.0044 17.3 0.6 0.017 15.4 0.1 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein CCSAP PF15748.5 GBG83780.1 - 2.9 8.0 44.8 2.4 8.3 16.8 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated FH2 PF02181.23 GBG83781.1 - 5.3e-111 371.3 0.2 8.7e-111 370.6 0.2 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.9 GBG83781.1 - 4.9e-25 87.9 0.1 7.9e-25 87.2 0.1 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DUF659 PF04937.15 GBG83782.1 - 9e-14 51.6 0.0 1.3e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Baculo_PEP_C PF04513.12 GBG83783.1 - 0.041 13.9 17.5 4.2 7.4 0.0 6.1 6 2 1 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus RT_RNaseH_2 PF17919.1 GBG83784.1 - 5.4e-23 80.9 0.0 1.7e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83784.1 - 2e-22 79.4 0.0 5.7e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG83784.1 - 2e-09 37.7 0.0 5.5e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Glycos_transf_3 PF00591.21 GBG83784.1 - 0.0048 16.5 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain DUF4192 PF13830.6 GBG83785.1 - 2 8.4 14.8 1.9 8.5 7.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) RT_RNaseH_2 PF17919.1 GBG83786.1 - 1.3e-33 115.0 0.4 3.9e-22 78.2 0.0 3.4 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83786.1 - 2.4e-30 104.9 0.1 5.4e-22 78.1 0.0 3.6 3 1 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83786.1 - 3.9e-27 95.2 0.1 7.6e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83786.1 - 4.4e-15 55.5 0.2 2e-14 53.4 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG83786.1 - 7.8e-09 35.8 0.0 2.6e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-RVT PF13966.6 GBG83786.1 - 1.4e-07 32.1 1.3 9.6e-07 29.4 0.4 2.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVP_2 PF08284.11 GBG83786.1 - 3.9e-06 26.7 0.0 8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83786.1 - 6.9e-06 26.6 0.0 2.3e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83786.1 - 1.8e-05 25.2 0.0 5.1e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Glycos_trans_3N PF02885.17 GBG83786.1 - 0.0076 16.1 0.0 0.032 14.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Asp_protease PF09668.10 GBG83786.1 - 0.023 14.5 0.0 0.077 12.8 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.12 GBG83786.1 - 1.7 9.3 6.0 5.4 7.7 0.4 3.0 2 0 0 2 2 2 0 SlyX RVT_1 PF00078.27 GBG83787.1 - 2e-17 63.5 0.7 9.7e-10 38.3 0.2 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Josephin PF02099.17 GBG83788.1 - 0.00076 19.6 0.0 0.0053 16.9 0.0 2.0 2 0 0 2 2 2 1 Josephin Pentapeptide PF00805.22 GBG83790.1 - 3.8e-15 55.2 15.3 6.8e-10 38.4 4.4 3.8 3 1 0 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 GBG83790.1 - 2.6e-10 40.3 1.3 7.9e-09 35.6 1.0 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 GBG83790.1 - 4.8e-09 36.2 8.7 1.1e-05 25.5 0.7 2.8 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) gag-asp_proteas PF13975.6 GBG83791.1 - 4.2e-06 27.2 0.0 1.2e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83791.1 - 0.00021 21.8 0.0 0.00055 20.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG83791.1 - 0.0065 16.3 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG83792.1 - 2.2e-31 107.8 0.0 8.7e-16 57.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83792.1 - 1.6e-30 105.5 0.0 3.7e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83792.1 - 4.4e-29 101.6 0.1 7.1e-29 100.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83792.1 - 1.2e-13 50.9 0.4 4.1e-13 49.2 0.5 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG83792.1 - 0.014 15.6 2.1 0.018 15.2 0.6 2.0 2 0 0 2 2 2 0 H2C2 zinc finger NTP_transferase PF00483.23 GBG83793.1 - 9.4e-73 244.8 0.0 1.3e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 GBG83793.1 - 0.0013 19.1 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 GBG83793.1 - 0.01 14.8 0.2 2.5 7.0 0.1 2.6 2 1 1 3 3 3 0 L-fucokinase Hexapep PF00132.24 GBG83793.1 - 0.45 10.3 11.1 0.06 13.1 2.2 2.8 3 0 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) Fasciclin PF02469.22 GBG83794.1 - 5.8e-17 62.1 0.0 3.4e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain PIF1 PF05970.14 GBG83795.1 - 3.7e-58 197.4 0.0 6.9e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase RT_RNaseH PF17917.1 GBG83797.1 - 2.4e-28 98.5 0.1 4.7e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83797.1 - 7.8e-22 77.2 0.0 1.5e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG83797.1 - 1.6e-07 31.5 0.0 4.3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG83798.1 - 3.4e-41 141.2 0.5 5.8e-27 94.6 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83798.1 - 1.4e-17 63.5 0.1 4e-17 62.1 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG83798.1 - 7.6e-05 22.5 0.2 0.026 14.4 0.0 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain EF-hand_7 PF13499.6 GBG83798.1 - 0.032 14.7 0.0 19 5.8 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain pair HNH_3 PF13392.6 GBG83798.1 - 0.061 13.1 0.1 6.8 6.5 0.0 2.6 2 0 0 2 2 2 0 HNH endonuclease RT_RNaseH PF17917.1 GBG83798.1 - 0.066 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG83798.1 - 0.12 12.7 0.0 0.86 9.9 0.0 2.5 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG83799.1 - 1.2e-26 93.7 0.1 2.2e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SR-25 PF10500.9 GBG83799.1 - 0.005 16.5 50.1 0.005 16.5 50.1 2.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein RT_RNaseH PF17917.1 GBG83800.1 - 1.2e-27 96.3 0.1 2.9e-27 95.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83800.1 - 1.4e-21 76.3 0.0 4.2e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83800.1 - 7.4e-17 61.2 0.1 1.7e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83800.1 - 1.1e-14 54.7 0.4 2.5e-14 53.5 0.1 1.8 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 GBG83800.1 - 1.7e-05 24.6 9.2 0.011 15.8 2.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 GBG83800.1 - 0.0018 18.2 3.1 0.97 9.4 0.7 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-H2C2 PF09337.10 GBG83800.1 - 0.077 13.2 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Trans_reg_C PF00486.28 GBG83800.1 - 0.12 12.5 0.2 0.36 10.9 0.2 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal zf-CCHC_4 PF14392.6 GBG83800.1 - 0.14 11.9 2.1 1.9 8.3 0.1 2.8 2 0 0 2 2 2 0 Zinc knuckle UPF0242 PF06785.11 GBG83800.1 - 7.6 6.6 7.4 24 5.0 7.4 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Retrotrans_gag PF03732.17 GBG83801.1 - 0.037 14.3 3.6 0.18 12.1 0.1 3.5 3 1 1 4 4 4 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG83801.1 - 0.047 14.3 0.0 0.28 11.9 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG83801.1 - 0.062 13.9 0.0 0.22 12.1 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 GBG83801.1 - 0.21 11.5 0.6 0.34 10.8 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle FAM76 PF16046.5 GBG83801.1 - 3.3 7.0 4.6 37 3.5 2.8 2.7 2 0 0 2 2 2 0 FAM76 protein rve PF00665.26 GBG83802.1 - 2.3e-18 66.5 0.0 5.2e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG83802.1 - 0.024 14.6 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain M16C_assoc PF08367.11 GBG83802.1 - 1.3 8.1 5.3 2.4 7.2 5.3 1.3 1 0 0 1 1 1 0 Peptidase M16C associated RT_RNaseH_2 PF17919.1 GBG83803.1 - 1.4e-33 114.9 0.0 3.5e-33 113.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83803.1 - 1.6e-20 73.3 0.0 3.6e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG83803.1 - 1.8e-06 28.4 0.0 5.9e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83803.1 - 0.00014 22.5 0.0 0.00032 21.3 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG83803.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG83803.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83803.1 - 0.0096 15.7 0.1 0.022 14.6 0.1 1.5 1 1 0 1 1 1 1 Aspartyl protease DsrH PF04077.12 GBG83804.1 - 4.5e-07 29.9 3.0 25 5.1 0.0 7.9 2 2 7 9 9 9 3 DsrH like protein Sm_like PF16243.5 GBG83804.1 - 4.1 7.6 6.7 12 6.1 0.1 3.8 2 1 1 4 4 4 0 Sm_like domain Retrotrans_gag PF03732.17 GBG83805.1 - 0.0058 16.9 0.0 0.025 14.9 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG83808.1 - 1.1e-18 67.6 0.0 2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83808.1 - 1.7e-17 63.3 0.0 4.1e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83808.1 - 1.4e-05 25.3 0.0 4.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG83808.1 - 0.013 15.5 1.2 0.03 14.3 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3863 PF12979.7 GBG83808.1 - 0.028 13.3 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) zf-CCHC PF00098.23 GBG83808.1 - 1.5 9.1 3.2 2.6 8.3 3.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Vfa1 PF08432.10 GBG83809.1 - 0.67 10.3 9.0 0.76 10.1 9.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Connexin PF00029.19 GBG83809.1 - 1.1 9.0 7.0 1.2 8.8 7.0 1.1 1 0 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 GBG83809.1 - 1.7 6.6 19.6 2 6.4 19.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi AAA_11 PF13086.6 GBG83809.1 - 2.1 8.1 7.2 2.3 7.9 7.2 1.0 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 GBG83809.1 - 2.2 6.5 15.9 2.3 6.4 15.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 GBG83809.1 - 4 5.4 6.9 4.4 5.3 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2201_N PF13203.6 GBG83809.1 - 4.3 6.9 11.7 5 6.6 11.7 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Afi1 PF07792.12 GBG83809.1 - 4.3 7.8 9.3 5.2 7.5 9.3 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 GBG83809.1 - 5.9 6.6 16.3 6.9 6.4 16.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.16 GBG83809.1 - 6.9 5.8 7.2 8.5 5.5 7.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop53 PF07767.11 GBG83809.1 - 7.6 5.8 27.7 9.3 5.5 27.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Presenilin PF01080.17 GBG83809.1 - 7.7 5.2 9.9 7.9 5.1 9.9 1.0 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG83810.1 - 2.7e-19 69.1 0.0 5.1e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83810.1 - 6.9e-18 64.9 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG83810.1 - 6.9e-08 33.0 0.0 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83810.1 - 1.5e-05 25.6 0.0 2.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG83810.1 - 9.6e-05 22.2 1.1 0.00016 21.4 1.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG83810.1 - 0.014 15.6 0.0 0.048 14.0 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease BUD22 PF09073.10 GBG83811.1 - 8.6 5.6 11.5 11 5.2 11.5 1.1 1 0 0 1 1 1 0 BUD22 zf-C3HC4_3 PF13920.6 GBG83812.1 - 5.8e-08 32.5 10.3 1.1e-07 31.6 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_1 PF00013.29 GBG83812.1 - 0.00021 21.0 0.0 0.00061 19.6 0.0 1.8 1 0 0 1 1 1 1 KH domain SDA1 PF05285.12 GBG83812.1 - 0.00058 19.4 5.9 0.00058 19.4 5.9 4.1 4 0 0 4 4 4 1 SDA1 zf-C3HC4 PF00097.25 GBG83812.1 - 0.0036 17.1 11.7 0.0071 16.2 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RNA_pol_3_Rpc31 PF11705.8 GBG83812.1 - 0.0052 17.1 7.8 0.0052 17.1 7.8 4.2 4 0 0 4 4 4 1 DNA-directed RNA polymerase III subunit Rpc31 zf-RING_5 PF14634.6 GBG83812.1 - 0.011 15.6 11.0 0.024 14.6 11.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG83812.1 - 0.048 13.5 11.7 0.1 12.5 11.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Chorion_S16 PF05836.12 GBG83813.1 - 0.38 11.0 4.2 0.62 10.3 4.2 1.3 1 0 0 1 1 1 0 Chorion protein S16 ATP-synt_F PF01990.17 GBG83815.1 - 0.026 14.8 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit RVT_1 PF00078.27 GBG83816.1 - 1.1e-31 110.1 0.0 1.8e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83816.1 - 6.9e-22 77.4 0.0 4.6e-16 58.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83816.1 - 1.5e-10 41.3 0.0 4.9e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG83816.1 - 1.6e-05 25.1 0.0 5.2e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-FLZ PF04570.14 GBG83817.1 - 1.8e-20 72.1 1.8 2.9e-20 71.5 1.8 1.3 1 0 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 RT_RNaseH_2 PF17919.1 GBG83819.1 - 7e-36 122.3 0.0 1.2e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83819.1 - 2.6e-23 82.3 0.0 5.1e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG83820.1 - 1.1e-12 48.0 0.0 2.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83820.1 - 9.5e-08 31.9 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG83820.1 - 0.037 14.4 1.4 0.068 13.6 0.1 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG83821.1 - 1.5e-07 31.6 4.1 2.9e-07 30.8 0.4 2.9 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83821.1 - 0.017 15.4 1.9 0.023 15.0 0.5 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4231 PF14015.6 GBG83822.1 - 2.9 8.4 5.9 3.5 8.1 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) RT_RNaseH_2 PF17919.1 GBG83823.1 - 1.1e-26 92.8 0.0 2.6e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83823.1 - 2.4e-25 89.3 0.0 5.1e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83823.1 - 1.1e-22 80.3 0.0 3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG83823.1 - 1.3e-06 28.9 0.0 3.3e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83823.1 - 3e-06 27.8 0.0 7.8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83823.1 - 2.3e-05 24.2 0.0 4.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG83823.1 - 4.7e-05 23.5 0.1 0.00013 22.1 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG83823.1 - 0.00016 21.5 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHH PF10283.9 GBG83823.1 - 0.022 14.7 1.3 0.072 13.1 0.2 2.4 2 0 0 2 2 2 0 PBZ domain Exo_endo_phos PF03372.23 GBG83824.1 - 9.2e-10 38.4 0.7 2.1e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 GBG83825.1 - 1e-35 123.3 0.0 1.6e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83825.1 - 4e-12 46.0 0.1 1.6e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83825.1 - 0.026 14.8 0.0 0.07 13.4 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF4790 PF16037.5 GBG83825.1 - 0.42 11.1 2.1 1.1 9.8 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4790) EF-hand_8 PF13833.6 GBG83826.1 - 2.9e-10 39.8 0.1 5e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 GBG83826.1 - 2e-07 31.4 0.4 5.6e-07 29.9 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GBG83826.1 - 4.9e-07 28.8 0.2 5.1e-06 25.7 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 GBG83826.1 - 5.6e-05 22.5 0.0 0.00013 21.3 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GBG83826.1 - 0.00018 21.2 0.1 0.0057 16.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain DUF309 PF03745.14 GBG83827.1 - 6e-21 73.9 0.4 1.1e-20 73.1 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF309) ANAPC3 PF12895.7 GBG83827.1 - 0.0011 19.1 0.2 0.0028 17.9 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 YfdX PF10938.8 GBG83827.1 - 0.16 11.9 2.6 0.31 11.0 2.6 1.4 1 0 0 1 1 1 0 YfdX protein Nbl1_Borealin_N PF10444.9 GBG83827.1 - 0.28 10.9 3.5 1.6 8.4 0.0 2.9 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DIM1 PF02966.16 GBG83828.1 - 9.7e-67 222.8 0.4 1.1e-66 222.6 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 GBG83828.1 - 0.00026 21.0 0.1 0.00034 20.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin RRM_1 PF00076.22 GBG83830.1 - 1.9e-07 30.8 0.0 3.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Integrase_H2C2 PF17921.1 GBG83831.1 - 3e-15 56.0 0.1 8.9e-15 54.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83831.1 - 5.9e-14 52.3 0.0 1.5e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG83831.1 - 1e-05 25.5 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83831.1 - 0.0022 18.2 0.0 0.005 17.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG83831.1 - 0.011 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG83832.1 - 1.9e-15 56.7 0.1 6.4e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83832.1 - 4e-14 52.8 0.0 1.1e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG83832.1 - 7.1e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83832.1 - 0.0015 18.8 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG83832.1 - 0.0074 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DNA_photolyase PF00875.18 GBG83833.1 - 9.9e-44 149.2 0.0 1.8e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase AIG1 PF04548.16 GBG83833.1 - 1.7e-05 24.2 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GBG83833.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GBG83833.1 - 0.015 15.7 1.4 0.074 13.4 0.6 2.4 2 1 0 2 2 2 0 AAA ATPase domain DUF1512 PF07431.12 GBG83833.1 - 0.047 12.7 0.1 0.096 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) zf-CCHC PF00098.23 GBG83834.1 - 1.4e-06 28.1 3.1 2.6e-06 27.3 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG83834.1 - 6.9e-05 22.6 7.6 0.00012 21.8 7.6 1.4 1 0 0 1 1 1 1 Zinc knuckle PI3K_1B_p101 PF10486.9 GBG83834.1 - 2.2 6.0 13.4 2.7 5.6 13.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DDE_Tnp_4 PF13359.6 GBG83835.1 - 2.2e-19 69.7 0.0 3.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83835.1 - 6.1e-11 42.3 0.0 2e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Plant transposon protein GrpE PF01025.19 GBG83836.1 - 9.2e-45 152.3 0.4 9.2e-45 152.3 0.4 1.8 1 1 1 2 2 2 1 GrpE HrpB7 PF09486.10 GBG83836.1 - 0.0064 16.9 5.9 0.0064 16.9 5.9 2.6 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) DUF5098 PF17023.5 GBG83836.1 - 0.019 14.0 0.3 0.032 13.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) YabA PF06156.13 GBG83836.1 - 1.2 9.8 7.2 0.13 12.9 1.2 2.3 2 1 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 GBG83836.1 - 1.7 9.0 4.4 0.7 10.2 0.9 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2408 PF10303.9 GBG83836.1 - 1.7 9.2 6.3 3.5 8.2 6.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Spc7 PF08317.11 GBG83836.1 - 2.1 7.2 10.2 1.6 7.5 8.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 GBG83836.1 - 8.4 5.6 10.3 16 4.8 10.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SOUL PF04832.12 GBG83837.1 - 6.1e-22 78.6 0.0 1.2e-21 77.6 0.0 1.5 2 0 0 2 2 2 1 SOUL heme-binding protein DUF2358 PF10184.9 GBG83837.1 - 4.9e-20 71.9 0.0 7.6e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) tRNA-synt_1b PF00579.25 GBG83838.1 - 4e-16 59.2 0.0 3.1e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) ATP-synt_D PF01813.17 GBG83840.1 - 0.56 10.0 2.0 0.72 9.7 2.0 1.2 1 0 0 1 1 1 0 ATP synthase subunit D Peptidase_C15 PF01470.17 GBG83843.1 - 3.8e-17 63.1 0.0 5.5e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase DUF4075 PF13294.6 GBG83843.1 - 0.15 12.2 0.0 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4075) RIIa PF02197.17 GBG83845.1 - 4.8e-06 26.1 0.0 8.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit TPH PF13868.6 GBG83846.1 - 0.088 11.3 93.9 0.33 9.4 92.6 2.0 1 1 0 1 1 1 0 Trichohyalin-plectin-homology domain RT_RNaseH_2 PF17919.1 GBG83850.1 - 1.7e-32 111.4 0.1 9.9e-32 109.0 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83850.1 - 6.4e-29 100.3 0.1 1.8e-28 98.9 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83850.1 - 2.7e-15 56.2 0.1 7.7e-15 54.7 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83850.1 - 0.00018 21.7 0.0 0.0019 18.4 0.0 2.7 1 1 1 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG83850.1 - 0.0011 18.5 0.1 0.0021 17.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG83850.1 - 0.052 13.8 0.6 0.23 11.8 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Chromo PF00385.24 GBG83850.1 - 0.096 12.6 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC_3 PF13917.6 GBG83850.1 - 0.21 11.6 4.3 0.13 12.3 1.8 1.9 2 0 0 2 2 2 0 Zinc knuckle TMF_TATA_bd PF12325.8 GBG83852.1 - 8.7e-25 87.2 4.7 8.7e-25 87.2 4.7 7.1 2 1 5 7 7 7 3 TATA element modulatory factor 1 TATA binding SSP160 PF06933.11 GBG83852.1 - 0.065 11.4 5.1 0.14 10.3 5.1 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TFA2_Winged_2 PF18121.1 GBG83852.1 - 4.2 7.1 5.6 5.9 6.7 0.1 4.0 3 1 1 4 4 4 0 TFA2 Winged helix domain 2 Pkinase PF00069.25 GBG83853.1 - 3.1e-45 154.6 0.0 4.4e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83853.1 - 1.1e-43 149.4 0.0 1.6e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRRNT_2 PF08263.12 GBG83853.1 - 6.4e-06 26.4 0.4 3.7e-05 23.9 0.4 2.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain APH PF01636.23 GBG83853.1 - 3.1e-05 24.0 0.8 0.00021 21.3 0.9 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family LRR_4 PF12799.7 GBG83853.1 - 0.00011 22.5 10.0 0.073 13.5 1.8 3.5 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG83853.1 - 0.00027 20.6 9.1 0.03 14.1 2.2 3.3 2 1 1 3 3 3 2 Leucine rich repeat ABC1 PF03109.16 GBG83853.1 - 0.017 15.2 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC1 family LRR_1 PF00560.33 GBG83853.1 - 0.21 12.3 6.4 19 6.3 0.1 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat RT_RNaseH PF17917.1 GBG83854.1 - 6.3e-29 100.3 0.1 1.7e-28 99.0 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83854.1 - 5.3e-28 97.0 0.2 1.8e-27 95.3 0.0 2.1 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG83854.1 - 3.2e-07 30.2 0.0 6.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG83854.1 - 5.8e-06 26.0 0.2 0.00015 21.4 0.1 2.3 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83854.1 - 9.8e-06 26.1 0.0 3.2e-05 24.5 0.0 1.9 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83854.1 - 0.0002 21.9 0.0 0.00062 20.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG83854.1 - 0.0032 17.2 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) EHN PF06441.12 GBG83854.1 - 0.0098 16.3 4.1 0.41 11.0 0.8 3.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Asp_protease PF09668.10 GBG83854.1 - 0.037 13.8 0.0 0.32 10.8 0.0 2.3 2 1 0 2 2 2 0 Aspartyl protease Presenilin PF01080.17 GBG83854.1 - 0.093 11.5 8.6 0.15 10.8 8.6 1.2 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 GBG83854.1 - 0.29 10.0 2.8 0.46 9.3 2.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Rrn6 PF10214.9 GBG83854.1 - 0.64 8.5 3.8 1 7.7 3.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2203 PF09969.9 GBG83854.1 - 0.87 10.3 7.4 67 4.2 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) Phage_GPO PF05929.11 GBG83854.1 - 3.9 7.0 11.0 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH PF17917.1 GBG83855.1 - 1.8e-11 44.3 0.0 3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83855.1 - 0.00045 20.2 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG83855.1 - 0.047 11.9 3.9 0.057 11.6 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG83855.1 - 0.088 13.1 9.2 0.14 12.4 9.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 GBG83855.1 - 0.62 9.4 7.1 0.83 9.0 7.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG83855.1 - 3.3 5.9 6.3 4.2 5.5 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MTH865 PF07747.11 GBG83856.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 MTH865-like family CI-B14_5a PF07347.12 GBG83857.1 - 0.022 14.6 2.2 0.064 13.1 0.5 2.7 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) CI-B14_5a PF07347.12 GBG83858.1 - 0.022 14.6 2.2 0.064 13.1 0.5 2.7 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) RVT_1 PF00078.27 GBG83859.1 - 5.7e-29 101.2 0.1 1e-28 100.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tub PF01167.18 GBG83859.1 - 1.2e-28 100.6 0.0 6.2e-17 62.2 0.0 2.4 2 0 0 2 2 2 2 Tub family RT_RNaseH PF17917.1 GBG83859.1 - 1.3e-21 76.8 0.0 3.9e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83859.1 - 1.6e-16 60.1 0.2 3.6e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG83859.1 - 2.9e-16 59.3 0.0 1.1e-15 57.5 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3527 PF12043.8 GBG83859.1 - 0.0098 15.5 0.0 0.0098 15.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) RVP_2 PF08284.11 GBG83859.1 - 0.052 13.3 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG83860.1 - 5.1e-29 101.4 0.1 9.2e-29 100.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83860.1 - 1.2e-21 77.0 0.0 3.6e-21 75.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Tub PF01167.18 GBG83860.1 - 2.6e-17 63.4 0.0 5.7e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Tub family Integrase_H2C2 PF17921.1 GBG83860.1 - 1.5e-16 60.2 0.2 3.3e-16 59.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG83860.1 - 2.5e-16 59.5 0.0 9.8e-16 57.6 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3527 PF12043.8 GBG83860.1 - 0.009 15.6 0.0 0.009 15.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) RVP_2 PF08284.11 GBG83860.1 - 0.047 13.4 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG83861.1 - 2.9e-28 97.8 0.0 4.7e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83861.1 - 3.3e-19 69.1 0.0 6.5e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83861.1 - 5.5e-11 42.4 0.1 8e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_3_Rpc31 PF11705.8 GBG83862.1 - 0.00061 20.1 5.0 0.00061 20.1 5.0 3.3 4 0 0 4 4 4 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 GBG83862.1 - 0.0023 17.4 12.9 0.026 13.9 1.9 3.0 3 0 0 3 3 3 2 BUD22 DUF2052 PF09747.9 GBG83862.1 - 0.088 12.9 21.7 0.78 9.8 5.8 2.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FYDLN_acid PF09538.10 GBG83862.1 - 0.13 13.0 14.3 1.6 9.5 3.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Myc_N PF01056.18 GBG83862.1 - 0.26 11.1 18.2 0.13 12.1 2.4 2.7 2 0 0 2 2 2 0 Myc amino-terminal region Connexin PF00029.19 GBG83862.1 - 0.4 10.4 5.3 4.2 7.1 0.2 2.4 2 0 0 2 2 2 0 Connexin RXT2_N PF08595.11 GBG83862.1 - 0.45 10.5 14.3 1.3 9.0 2.2 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal RR_TM4-6 PF06459.12 GBG83862.1 - 0.47 10.2 16.1 0.28 11.0 2.8 2.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG83862.1 - 0.51 9.7 24.6 0.13 11.7 5.8 2.4 2 0 0 2 2 2 0 SDA1 SpoIIP PF07454.11 GBG83862.1 - 2.2 7.7 9.4 6.7 6.1 0.7 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.10 GBG83862.1 - 3.3 8.0 12.1 2.1 8.6 1.2 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Thg1C PF14413.6 GBG83862.1 - 5.1 7.3 7.1 7.7 6.7 0.2 2.8 2 0 0 2 2 2 0 Thg1 C terminal domain GEN1_C PF18380.1 GBG83862.1 - 8.4 7.4 15.3 0.74 10.7 2.6 3.0 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain FAM176 PF14851.6 GBG83862.1 - 8.5 6.0 19.6 4.4 6.9 5.4 2.6 2 0 0 2 2 2 0 FAM176 family DUF4139 PF13598.6 GBG83863.1 - 1.6 8.4 7.7 2.2 7.9 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) CDC27 PF09507.10 GBG83863.1 - 5.7 6.2 27.3 6.8 6.0 27.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 eIF3_p135 PF12807.7 GBG83865.1 - 1.2e-31 110.1 0.0 2.5e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 GBG83865.1 - 6.6e-05 23.1 0.1 0.00018 21.8 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat CLU_N PF15044.6 GBG83865.1 - 0.0004 20.7 0.2 0.0007 19.9 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term CLU PF13236.6 GBG83865.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Clustered mitochondria Gcd10p PF04189.13 GBG83865.1 - 0.07 12.2 3.1 0.13 11.4 3.1 1.3 1 0 0 1 1 1 0 Gcd10p family TPR_10 PF13374.6 GBG83865.1 - 0.13 12.2 0.1 18 5.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Zip PF02535.22 GBG83867.1 - 1.4e-56 192.1 16.3 2e-56 191.6 16.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4149 PF13664.6 GBG83867.1 - 1.5 9.2 8.4 0.16 12.3 0.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) COX7a PF02238.15 GBG83867.1 - 8.1 6.9 7.2 0.52 10.8 0.5 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII DDE_Tnp_4 PF13359.6 GBG83868.1 - 1.3e-17 63.9 0.0 4.7e-17 62.1 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83868.1 - 4.1e-08 33.1 0.0 6.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83868.1 - 0.0007 19.3 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG83869.1 - 1.4e-07 31.8 2.3 2.1e-07 31.2 2.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83869.1 - 0.0012 19.1 0.3 0.0027 18.0 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG83869.1 - 0.0062 16.6 1.1 0.0096 16.0 1.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG83869.1 - 0.028 14.6 0.9 0.057 13.6 0.9 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG83870.1 - 1.1e-07 32.1 0.3 1.8e-07 31.4 0.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG83870.1 - 0.0047 17.0 0.6 0.0088 16.1 0.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83870.1 - 0.0061 16.8 0.4 0.011 16.0 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BRI3BP PF14965.6 GBG83870.1 - 0.25 10.9 1.1 0.39 10.2 1.1 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DDE_Tnp_4 PF13359.6 GBG83871.1 - 2.2e-25 89.2 0.0 2.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83871.1 - 7.9e-16 58.3 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83871.1 - 0.00015 21.5 0.3 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain Rieske PF00355.26 GBG83872.1 - 2.9e-17 62.4 0.0 8.3e-17 60.9 0.0 1.7 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG83872.1 - 8.6e-08 32.2 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Pheophorbide a oxygenase RVT_1 PF00078.27 GBG83873.1 - 1.2e-27 96.9 0.0 1.7e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG83873.1 - 3.3e-09 36.6 0.0 6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83873.1 - 1.2e-08 35.4 0.0 2.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83873.1 - 4.8e-06 27.0 0.0 9.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83873.1 - 0.002 17.9 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG83875.1 - 1.6e-07 31.6 1.2 1.6e-07 31.6 1.2 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SUR7 PF06687.12 GBG83875.1 - 9 5.9 22.3 16 5.0 22.3 1.4 1 0 0 1 1 1 0 SUR7/PalI family RT_RNaseH_2 PF17919.1 GBG83876.1 - 6.4e-34 116.0 0.2 2.9e-33 113.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83876.1 - 3.3e-30 104.5 0.0 1e-29 102.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83876.1 - 6.4e-24 84.7 0.1 1.5e-23 83.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83876.1 - 1.1e-15 57.4 0.3 2.8e-15 56.2 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF2383 PF09537.10 GBG83876.1 - 0.015 15.6 2.3 0.045 14.1 2.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Retrotrans_gag PF03732.17 GBG83876.1 - 0.032 14.5 0.6 1 9.7 0.1 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein Phage_GPO PF05929.11 GBG83876.1 - 0.18 11.4 0.1 0.18 11.4 0.1 3.0 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Integrase_H2C2 PF17921.1 GBG83877.1 - 1.2e-14 54.2 0.0 2.8e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG83877.1 - 3.6e-09 36.9 0.1 1e-08 35.4 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG83877.1 - 2.5e-07 30.5 0.0 5.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83877.1 - 1e-06 29.3 0.0 3.3e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83877.1 - 2.7e-05 24.6 0.0 7.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83877.1 - 0.00053 19.8 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG83877.1 - 0.0019 18.4 0.4 0.086 13.1 0.0 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG83877.1 - 0.011 15.9 0.0 0.038 14.2 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain zf-CCHC PF00098.23 GBG83877.1 - 0.069 13.3 0.6 0.19 11.9 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG83878.1 - 1.4e-32 111.7 0.1 4.8e-32 110.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83878.1 - 3.2e-27 94.9 0.0 7.7e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83878.1 - 4.8e-11 42.6 0.3 8.7e-11 41.8 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG83878.1 - 5.4e-05 23.7 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83878.1 - 0.0016 19.0 0.0 0.0033 18.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG83878.1 - 0.044 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG83878.1 - 0.18 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG83879.1 - 1.2e-32 111.8 0.1 4.5e-32 110.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83879.1 - 2.9e-27 95.0 0.0 7.2e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83879.1 - 4.5e-11 42.7 0.3 8.2e-11 41.8 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG83879.1 - 5e-05 23.8 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83879.1 - 0.0015 19.1 0.0 0.0031 18.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG83879.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG83879.1 - 0.17 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG83880.1 - 1.7e-30 105.0 0.0 6.6e-30 103.1 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83880.1 - 1.7e-29 102.1 0.1 4.6e-29 100.8 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LRR_4 PF12799.7 GBG83880.1 - 6e-18 64.7 18.2 3.6e-05 24.0 1.7 7.3 5 1 3 8 8 8 4 Leucine Rich repeats (2 copies) Integrase_H2C2 PF17921.1 GBG83880.1 - 1.3e-16 60.4 0.1 3.6e-16 59.0 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain LRR_8 PF13855.6 GBG83880.1 - 1.3e-15 56.9 16.6 9.6e-06 25.3 0.0 5.1 3 2 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 GBG83880.1 - 1.9e-09 37.2 0.0 4e-07 29.7 0.0 3.4 3 0 0 3 3 3 1 Leucine-rich repeat RVT_1 PF00078.27 GBG83880.1 - 1.1e-07 31.7 1.3 0.00024 20.7 0.0 3.2 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_6 PF13516.6 GBG83880.1 - 1.4e-05 24.8 4.5 0.71 10.1 0.3 6.1 5 0 0 5 5 5 1 Leucine Rich repeat IQ PF00612.27 GBG83880.1 - 0.00012 21.6 1.8 0.00012 21.6 1.8 4.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif rve PF00665.26 GBG83880.1 - 0.00028 21.1 0.0 0.00082 19.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG83880.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger LRR_1 PF00560.33 GBG83880.1 - 3.7 8.5 14.0 57 4.9 0.7 6.8 8 0 0 8 8 7 0 Leucine Rich Repeat RVT_1 PF00078.27 GBG83881.1 - 1.5e-28 99.8 0.0 2.3e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FOP_dimer PF09398.10 GBG83881.1 - 1.8e-08 34.5 0.0 4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 GBG83881.1 - 4.3e-08 32.0 0.2 8e-08 31.2 0.2 1.4 1 0 0 1 1 1 1 LisH zf-CCHC PF00098.23 GBG83881.1 - 0.00058 19.8 2.7 0.0012 18.8 2.7 1.5 1 0 0 1 1 1 1 Zinc knuckle SesA PF17107.5 GBG83881.1 - 0.053 13.7 2.3 13 6.0 0.0 3.7 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-CCHC_2 PF13696.6 GBG83881.1 - 0.085 12.7 5.3 0.19 11.6 5.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Tau95_N PF17682.1 GBG83881.1 - 1.8 8.7 5.9 5.5 7.2 5.9 1.8 1 0 0 1 1 1 0 Tau95 Triple barrel domain Sec6 PF06046.13 GBG83881.1 - 6.5 5.0 8.2 11 4.3 8.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec6 Nop14 PF04147.12 GBG83882.1 - 0.01 14.1 41.7 0.012 13.9 41.7 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG83882.1 - 0.014 13.9 30.0 0.017 13.6 30.0 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 GBG83882.1 - 0.17 11.2 33.3 0.2 10.9 33.3 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 GBG83882.1 - 0.21 10.9 32.9 0.28 10.5 32.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 GBG83882.1 - 0.23 10.8 43.0 0.31 10.4 43.0 1.2 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 GBG83882.1 - 0.38 9.2 38.4 0.6 8.6 38.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 GBG83882.1 - 1.2 7.9 16.1 1.3 7.7 16.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 GBG83882.1 - 1.8 7.7 4.5 2.4 7.3 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 GBG83882.1 - 3.9 6.4 11.2 6.4 5.6 11.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) UPF0524 PF15823.5 GBG83883.1 - 0.19 11.1 3.0 0.39 10.1 2.5 1.6 1 1 0 1 1 1 0 UPF0524 of C3orf70 Chromo PF00385.24 GBG83884.1 - 0.0032 17.4 0.1 0.0051 16.7 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2457 PF10446.9 GBG83884.1 - 0.034 13.3 15.2 0.059 12.5 15.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GCIP PF13324.6 GBG83884.1 - 0.094 12.3 2.3 0.12 12.0 2.3 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RXT2_N PF08595.11 GBG83884.1 - 0.099 12.7 3.8 0.18 11.8 3.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 GBG83884.1 - 0.18 11.4 1.7 0.32 10.6 1.7 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 GBG83884.1 - 0.2 11.0 14.0 0.32 10.3 14.0 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GBG83884.1 - 0.3 9.2 3.5 0.35 9.0 3.5 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG83884.1 - 0.33 10.4 4.8 0.45 9.9 4.8 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG83884.1 - 0.43 10.3 13.4 0.66 9.7 13.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 GBG83884.1 - 0.43 10.4 3.6 0.57 10.0 3.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.11 GBG83884.1 - 0.49 9.9 3.4 0.57 9.7 3.4 1.1 1 0 0 1 1 1 0 PPP4R2 YL1 PF05764.13 GBG83884.1 - 0.7 10.0 5.4 1.1 9.3 5.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CENP-B_dimeris PF09026.10 GBG83884.1 - 5.4 7.5 24.4 11 6.5 24.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RVP_2 PF08284.11 GBG83885.1 - 2e-09 37.4 0.0 4.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83885.1 - 2.2e-08 34.6 0.0 7.3e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83885.1 - 1e-06 29.2 0.0 3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG83885.1 - 0.00019 21.2 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG83885.1 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG83885.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ORF6C PF10552.9 GBG83885.1 - 0.11 12.6 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 ORF6C domain Cation_ATPase_N PF00690.26 GBG83887.1 - 1.5e-16 59.9 0.0 2.4e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus L_protein_N PF15518.6 GBG83887.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 L protein N-terminus RT_RNaseH_2 PF17919.1 GBG83888.1 - 7e-33 112.6 0.0 2.5e-32 110.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83888.1 - 2.7e-27 95.1 1.2 1.9e-26 92.4 0.0 3.0 4 0 0 4 4 4 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83888.1 - 3e-23 82.5 0.1 5.7e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83888.1 - 5.6e-18 64.8 0.4 1.1e-17 63.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG83888.1 - 0.06 14.0 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF2805 PF10985.8 GBG83888.1 - 0.1 13.0 0.0 0.41 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) gag-asp_proteas PF13975.6 GBG83888.1 - 0.16 12.5 0.0 0.42 11.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Phage_GPO PF05929.11 GBG83888.1 - 0.24 11.0 4.6 6.1 6.4 0.0 2.8 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase CENP-Q PF13094.6 GBG83888.1 - 0.39 10.9 4.6 0.96 9.6 4.6 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit E1-E2_ATPase PF00122.20 GBG83889.1 - 1e-07 31.7 0.2 2e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase DUF4992 PF16383.5 GBG83889.1 - 0.048 13.2 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function CIAPIN1 PF05093.13 GBG83889.1 - 1.3 9.6 7.1 0.2 12.2 1.9 2.4 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Cation_ATPase_C PF00689.21 GBG83890.1 - 2.3e-37 128.5 0.3 1e-36 126.3 0.3 1.9 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus RT_RNaseH_2 PF17919.1 GBG83890.1 - 7.7e-25 86.8 0.0 6.8e-24 83.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83890.1 - 6e-21 75.0 0.1 1.6e-17 63.8 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83890.1 - 1e-20 74.0 0.0 3.4e-20 72.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Hydrolase PF00702.26 GBG83890.1 - 6.5e-17 62.5 0.0 7.4e-16 59.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Integrase_H2C2 PF17921.1 GBG83890.1 - 3.5e-16 59.0 0.1 9.9e-16 57.6 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83890.1 - 8.2e-09 35.7 0.0 2.2e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG83890.1 - 1.5e-06 28.7 0.0 5.1e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83890.1 - 3.8e-06 27.4 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG83890.1 - 3.6e-05 23.5 0.0 7.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83890.1 - 0.0013 18.6 0.0 0.0049 16.7 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Cation_ATPase PF13246.6 GBG83890.1 - 0.003 17.6 0.0 0.0086 16.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GBG83890.1 - 0.0059 16.4 0.5 0.0059 16.4 0.5 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GBG83890.1 - 0.034 14.6 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Chromo PF00385.24 GBG83890.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Helo_like_N PF17111.5 GBG83890.1 - 1.5 8.2 6.3 2.1 7.7 0.7 2.9 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF5069 PF16798.5 GBG83890.1 - 1.6 8.9 4.1 0.96 9.6 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) DUF1664 PF07889.12 GBG83890.1 - 5.3 7.1 10.2 0.45 10.6 2.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Tim44 PF04280.15 GBG83891.1 - 7.4e-29 100.8 0.5 1.1e-28 100.1 0.5 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 GBG83891.1 - 0.008 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein RVT_1 PF00078.27 GBG83892.1 - 9e-29 100.6 0.1 1.5e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83892.1 - 2.1e-26 91.9 0.1 7.7e-26 90.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83892.1 - 5e-25 87.8 0.1 1.5e-24 86.3 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG83892.1 - 7.4e-08 32.9 0.0 1.6e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83892.1 - 4.4e-07 29.7 0.0 9.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG83892.1 - 6.3e-05 23.5 0.0 0.00025 21.5 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG83892.1 - 0.0082 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG83892.1 - 0.026 14.3 0.0 0.083 12.7 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease Cation_ATPase_N PF00690.26 GBG83893.1 - 1.4e-15 56.7 0.0 2.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Herpes_gE PF02480.16 GBG83893.1 - 0.019 13.7 0.0 0.069 11.9 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E HBS1_N PF08938.10 GBG83893.1 - 0.025 14.8 0.1 0.093 13.0 0.1 1.9 2 0 0 2 2 2 0 HBS1 N-terminus DUF4401 PF14351.6 GBG83893.1 - 0.052 12.9 0.3 0.079 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) RT_RNaseH_2 PF17919.1 GBG83894.1 - 1.3e-25 89.3 0.0 1.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83894.1 - 7.9e-22 77.5 0.0 1.1e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83895.1 - 3.9e-19 69.1 0.0 5e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_lysozyme PF00959.19 GBG83895.1 - 0.00028 21.3 0.4 5.9 7.4 0.0 3.6 3 0 0 3 3 3 2 Phage lysozyme E1-E2_ATPase PF00122.20 GBG83895.1 - 0.00051 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase TGT_C1 PF14809.6 GBG83895.1 - 0.11 12.8 1.2 18 5.7 0.1 2.6 2 0 0 2 2 2 0 C1 domain of tRNA-guanine transglycosylase dimerisation DUF919 PF06034.11 GBG83895.1 - 0.14 12.0 1.2 0.36 10.7 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) RVT_1 PF00078.27 GBG83896.1 - 1.5e-28 99.9 0.2 3.4e-28 98.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83896.1 - 2.2e-24 85.4 0.0 5.3e-24 84.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83896.1 - 8.1e-24 83.9 0.0 1.4e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrin_b_cyt PF08725.11 GBG83896.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain ApbE PF02424.15 GBG83899.1 - 1.1e-51 175.9 0.1 3.1e-37 128.5 0.0 2.1 2 0 0 2 2 2 2 ApbE family DUF659 PF04937.15 GBG83901.1 - 6.7e-22 78.0 0.0 1.2e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG83901.1 - 3.6e-08 33.1 0.2 1e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG83902.1 - 0.00028 21.4 0.0 0.0005 20.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83902.1 - 0.0061 17.2 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG83904.1 - 1.3e-22 80.4 0.1 2.2e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83904.1 - 6.1e-22 77.5 0.0 1.6e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83904.1 - 2.5e-13 50.2 0.0 4.6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG83904.1 - 3.4e-08 33.3 0.0 7.6e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83904.1 - 2.7e-05 24.7 0.0 5.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83904.1 - 0.0039 17.7 0.0 0.0076 16.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG83904.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG83905.1 - 3.4e-35 120.1 0.0 5.9e-35 119.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83905.1 - 2.7e-32 112.1 0.1 4e-32 111.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83905.1 - 2.8e-32 111.1 0.0 5.3e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83905.1 - 1.8e-09 37.5 0.0 4.4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF5095 PF17016.5 GBG83905.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) zf-CCHC_3 PF13917.6 GBG83906.1 - 0.086 12.8 1.8 0.19 11.7 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG83908.1 - 0.0072 16.6 0.4 0.036 14.3 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein LLC1 PF14945.6 GBG83908.1 - 0.017 15.7 0.0 0.053 14.1 0.0 1.8 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein NPV_P10 PF05531.12 GBG83908.1 - 0.075 13.5 1.4 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4939 PF16297.5 GBG83908.1 - 0.19 11.6 0.0 0.47 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Fmp27_WPPW PF10359.9 GBG83908.1 - 3.4 6.4 5.6 21 3.8 5.7 2.0 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4239 PF14023.6 GBG83908.1 - 6.2 6.5 5.3 1.4 8.6 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) RT_RNaseH PF17917.1 GBG83909.1 - 4.9e-19 68.6 0.0 1.1e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83909.1 - 9.1e-14 51.3 0.1 1.8e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG83909.1 - 3.4e-09 36.6 0.0 8.5e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG83909.1 - 0.00028 21.1 0.0 1.4 9.2 0.0 3.0 2 0 0 2 2 2 2 Retrotransposon gag protein ADP_ribosyl_GH PF03747.14 GBG83909.1 - 0.12 12.0 0.3 1.9 8.1 0.3 2.6 2 1 0 2 2 2 0 ADP-ribosylglycohydrolase RasGEF_N PF00618.20 GBG83909.1 - 0.14 12.4 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 RasGEF N-terminal motif Phage_GPO PF05929.11 GBG83909.1 - 0.33 10.5 0.0 0.33 10.5 0.0 2.6 4 0 0 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF659 PF04937.15 GBG83910.1 - 1.4e-20 73.7 0.2 2.5e-20 72.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2333 PF10095.9 GBG83911.1 - 1 8.3 6.5 3.9 6.4 6.5 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Med9 PF07544.13 GBG83911.1 - 4.1 7.6 19.3 0.97 9.6 0.7 3.8 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Rgp1 PF08737.10 GBG83911.1 - 8.1 5.5 9.5 11 5.1 9.5 1.2 1 0 0 1 1 1 0 Rgp1 RVT_1 PF00078.27 GBG83912.1 - 2.9e-28 98.9 0.1 4.7e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG83912.1 - 3.8e-09 36.8 0.0 1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG83912.1 - 0.0049 17.5 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG83913.1 - 3.1e-16 59.5 0.0 6.5e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83913.1 - 1.7e-15 56.9 0.1 1.5e-14 53.8 0.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG83913.1 - 1.6e-11 44.4 0.0 4.4e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG83913.1 - 7.5e-08 32.2 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG83913.1 - 0.0023 18.1 0.0 0.0087 16.3 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG83913.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG83913.1 - 0.0067 17.1 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83913.1 - 0.015 15.9 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease eIF-1a PF01176.19 GBG83913.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Integrase_H2C2 PF17921.1 GBG83914.1 - 8.5e-15 54.6 0.0 2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG83914.1 - 1.1e-13 51.3 0.8 2.6e-13 50.2 0.8 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83914.1 - 1.2e-05 25.3 0.7 2.4e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Acid_PPase PF12689.7 GBG83914.1 - 0.079 12.8 1.8 0.85 9.4 0.1 2.7 3 0 0 3 3 3 0 Acid Phosphatase RT_RNaseH_2 PF17919.1 GBG83915.1 - 3.3e-29 100.9 0.0 6.7e-29 99.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83915.1 - 1.1e-28 100.2 0.1 2.5e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG83915.1 - 1.2e-25 89.8 0.0 2.3e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83915.1 - 6.2e-08 32.6 0.0 1.7e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Integrase_H2C2 PF17921.1 GBG83916.1 - 5.2e-36 122.5 2.9 2e-18 66.2 0.2 2.9 3 0 0 3 3 3 2 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG83916.1 - 2.6e-33 114.0 0.0 5.8e-17 61.6 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83916.1 - 3.8e-32 110.7 0.8 2e-24 85.9 0.2 3.3 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83916.1 - 1.1e-15 57.8 0.3 5.3e-15 55.5 0.1 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG83916.1 - 2.8e-08 33.8 0.0 0.00068 19.8 0.0 2.8 2 0 0 2 2 2 2 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG83916.1 - 3.1e-05 24.5 0.4 0.00016 22.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83916.1 - 0.00075 20.0 1.1 0.0031 18.0 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG83916.1 - 0.00076 19.7 0.7 0.22 11.8 0.0 3.3 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG83916.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG83916.1 - 0.05 13.4 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 GBG83917.1 - 6.1e-11 42.6 0.0 2.3e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG83917.1 - 0.0025 18.1 0.1 0.0025 18.1 0.1 2.3 3 0 0 3 3 3 1 Retrotransposon gag protein Tudor-knot PF11717.8 GBG83917.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain SlyX PF04102.12 GBG83917.1 - 0.053 14.2 0.1 0.053 14.2 0.1 3.5 4 0 0 4 4 4 0 SlyX Cnn_1N PF07989.11 GBG83917.1 - 0.09 12.9 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 GBG83917.1 - 0.39 10.9 2.9 1.9 8.7 0.1 2.7 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II RT_RNaseH_2 PF17919.1 GBG83918.1 - 2.2e-44 149.5 2.2 1.4e-31 108.5 0.0 3.7 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83918.1 - 8.2e-36 122.5 0.1 1.3e-28 99.4 0.1 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83918.1 - 7.6e-35 120.4 0.2 2.4e-24 86.1 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG83918.1 - 0.023 15.0 0.2 0.14 12.5 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Phage_GPO PF05929.11 GBG83918.1 - 0.044 13.4 0.8 0.87 9.2 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase MCLC PF05934.11 GBG83918.1 - 0.047 12.4 1.8 0.066 11.9 1.8 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Zip PF02535.22 GBG83919.1 - 1.9e-33 116.1 0.2 2.4e-33 115.7 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter ATP_synt_H PF05493.13 GBG83919.1 - 2.4 8.7 5.4 8.7 6.9 0.8 2.7 3 0 0 3 3 3 0 ATP synthase subunit H Wzy_C PF04932.15 GBG83919.1 - 8.4 6.0 8.1 0.53 9.9 0.2 2.4 2 1 0 2 2 2 0 O-Antigen ligase Zip PF02535.22 GBG83921.1 - 5.4e-26 91.6 19.3 6.6e-25 88.0 19.3 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Ldl_recept_a PF00057.18 GBG83922.1 - 1.8e-34 117.6 136.5 1.1e-05 25.5 9.2 11.2 10 1 0 11 11 11 10 Low-density lipoprotein receptor domain class A Cupin_1 PF00190.22 GBG83924.1 - 3.2e-44 150.2 0.9 1.2e-31 109.3 0.4 2.4 2 1 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GBG83924.1 - 1.7e-06 27.6 0.0 0.034 13.9 0.0 2.7 2 0 0 2 2 2 2 Cupin domain RT_RNaseH PF17917.1 GBG83926.1 - 6.3e-15 55.3 0.0 1.5e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG83926.1 - 4.8e-12 45.8 0.0 8.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83926.1 - 1.4e-10 41.1 0.0 2.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PI3K_1B_p101 PF10486.9 GBG83927.1 - 0.03 12.1 1.0 0.048 11.5 1.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SR-25 PF10500.9 GBG83927.1 - 5.3 6.6 8.9 0.81 9.3 2.6 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 GBG83928.1 - 5.3 5.2 15.1 10 4.3 15.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Integrase_H2C2 PF17921.1 GBG83930.1 - 1.2e-15 57.4 0.2 2.9e-15 56.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83930.1 - 0.00026 21.1 0.0 0.00055 20.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG83930.1 - 0.005 17.0 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF2570 PF10828.8 GBG83930.1 - 1.3 8.9 4.9 1.1 9.1 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) gag-asp_proteas PF13975.6 GBG83931.1 - 4.4e-05 24.0 0.0 0.0001 22.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG83931.1 - 0.00012 22.0 0.0 0.00044 20.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83931.1 - 0.00077 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83931.1 - 0.0023 18.5 0.0 0.0055 17.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG83931.1 - 0.0027 18.0 0.0 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase SlyX PF04102.12 GBG83932.1 - 3 8.5 10.2 0.13 12.9 2.8 2.7 2 0 0 2 2 2 0 SlyX LMBR1 PF04791.16 GBG83933.1 - 1.1 8.1 4.6 1.3 7.8 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribonuc_red_2_N PF08471.10 GBG83933.1 - 5.5 7.2 6.1 1.7 8.9 2.7 1.9 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase RT_RNaseH_2 PF17919.1 GBG83936.1 - 2.8e-31 107.5 0.0 5.4e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83936.1 - 1.8e-27 95.7 0.1 3.6e-27 94.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83936.1 - 1.8e-09 37.5 0.1 2.9e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) cNMP_binding PF00027.29 GBG83936.1 - 6.5e-09 35.7 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Fe_dep_repress PF01325.19 GBG83936.1 - 0.0045 17.2 0.2 0.016 15.4 0.0 2.0 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain RVT_1 PF00078.27 GBG83937.1 - 2.3e-32 112.3 0.1 4.2e-32 111.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83937.1 - 3e-28 97.8 0.0 8.1e-28 96.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83937.1 - 2.1e-27 95.4 0.2 5.7e-27 94.1 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83937.1 - 1e-08 35.1 0.5 2.6e-08 33.8 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG83937.1 - 4.1e-06 27.0 0.0 6.2e-05 23.2 0.0 2.9 2 1 0 2 2 2 1 Integrase core domain DUF5095 PF17016.5 GBG83937.1 - 0.061 13.0 0.3 0.16 11.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Sporozoite_P67 PF05642.11 GBG83937.1 - 0.16 10.0 1.0 0.23 9.5 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LegC3_N PF18654.1 GBG83937.1 - 2.2 7.5 6.1 4.8 6.3 6.1 1.5 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain Asp_protease_2 PF13650.6 GBG83938.1 - 2.5e-07 31.2 0.0 6.7e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83938.1 - 7.1e-06 26.5 0.0 2.4e-05 24.8 0.0 2.0 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG83938.1 - 4e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG83938.1 - 5.5e-05 22.9 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG83938.1 - 0.0032 17.7 6.4 0.022 15.0 0.0 3.8 4 0 0 4 4 4 1 Retrotransposon gag protein Fib_alpha PF08702.10 GBG83938.1 - 0.055 13.7 1.0 3 8.0 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 GBG83938.1 - 0.33 11.4 2.6 0.74 10.3 0.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 GBG83938.1 - 0.47 10.9 4.2 2.3 8.6 1.8 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 GBG83938.1 - 1.5 8.1 12.0 2.3 7.5 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SNAPc19 PF15497.6 GBG83938.1 - 2.1 8.9 6.4 0.65 10.5 0.1 2.9 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Adaptin_binding PF10199.9 GBG83938.1 - 2.3 8.8 6.3 7.5 7.2 6.3 1.8 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SPARC_Ca_bdg PF10591.9 GBG83938.1 - 3 8.2 5.4 1.4 9.2 1.5 2.6 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region RVT_1 PF00078.27 GBG83939.1 - 3e-26 92.3 0.0 4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83939.1 - 8.2e-11 41.8 0.0 2.7e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83939.1 - 0.0029 17.9 0.0 0.0069 16.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DFF40 PF09230.10 GBG83939.1 - 0.092 12.4 0.2 0.19 11.3 0.2 1.5 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa Imm5 PF14423.6 GBG83941.1 - 0.031 14.5 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 ATP-synt_B PF00430.18 GBG83941.1 - 0.04 14.0 3.4 0.04 14.0 3.4 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) ERM PF00769.19 GBG83941.1 - 4.3 7.1 26.3 0.73 9.6 5.1 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family cNMP_binding PF00027.29 GBG83942.1 - 1.2e-07 31.7 0.0 9.2e-06 25.7 0.0 3.0 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain DUF659 PF04937.15 GBG83943.1 - 2.2e-13 50.3 0.0 4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG83944.1 - 1.4e-27 96.0 0.1 3.3e-27 94.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83944.1 - 1e-19 70.3 0.3 1e-19 70.3 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG83944.1 - 1.1e-19 70.3 0.1 2.7e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83944.1 - 9.1e-08 31.9 0.0 2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG83944.1 - 2e-07 30.8 0.0 4.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG83944.1 - 4e-06 27.4 0.0 1.1e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease cNMP_binding PF00027.29 GBG83944.1 - 2.2e-05 24.4 0.0 0.0076 16.3 0.0 2.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain gag-asp_proteas PF13975.6 GBG83944.1 - 3.4e-05 24.3 0.0 8.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG83944.1 - 0.0021 18.2 0.3 0.0091 16.2 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease PF09668.10 GBG83944.1 - 0.0075 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG83944.1 - 0.0083 16.3 0.1 0.019 15.1 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DUF2057 PF09829.9 GBG83944.1 - 0.063 13.4 0.1 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) RVT_1 PF00078.27 GBG83945.1 - 2.7e-31 108.8 0.1 5.1e-31 107.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG83945.1 - 3.5e-30 104.0 0.0 7.5e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83945.1 - 4e-26 91.4 0.0 9.3e-26 90.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG83945.1 - 7.3e-14 51.6 3.4 2.4e-13 50.0 0.1 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG83945.1 - 1.9e-07 30.9 0.0 4.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG83945.1 - 9.4e-06 25.8 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG83945.1 - 9.5e-06 26.2 0.0 7.8e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG83945.1 - 2.8e-05 23.9 0.0 5.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83945.1 - 5.5e-05 23.7 0.0 0.00018 22.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG83945.1 - 0.0074 16.5 0.0 0.035 14.3 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger Rhamno_transf PF11316.8 GBG83945.1 - 0.075 12.4 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative rhamnosyl transferase RT_RNaseH_2 PF17919.1 GBG83946.1 - 4.2e-34 116.6 0.1 2.4e-33 114.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83946.1 - 5.9e-31 106.9 0.3 2.2e-30 105.0 0.3 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83946.1 - 8e-18 64.8 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG83946.1 - 3.7e-15 56.2 0.1 1.7e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG83946.1 - 9.4e-05 22.3 0.0 0.074 13.0 0.0 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain FtsK_4TM PF13491.6 GBG83946.1 - 0.005 16.6 0.1 0.0087 15.8 0.1 1.2 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE IceA2 PF05862.11 GBG83946.1 - 0.01 15.7 0.3 0.021 14.7 0.3 1.5 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein zf-CCHC_3 PF13917.6 GBG83946.1 - 0.017 15.1 2.4 0.043 13.8 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG83946.1 - 0.022 15.1 0.1 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein DUF5095 PF17016.5 GBG83946.1 - 0.76 9.4 2.5 0.5 10.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) NOA36 PF06524.12 GBG83947.1 - 0.0049 16.2 10.0 0.0049 16.2 10.0 1.1 1 0 0 1 1 1 1 NOA36 protein SDA1 PF05285.12 GBG83947.1 - 0.013 15.0 11.5 0.012 15.0 11.5 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG83947.1 - 0.13 10.5 15.0 0.11 10.7 15.0 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 GBG83947.1 - 0.19 11.3 14.1 0.16 11.5 14.1 1.0 1 0 0 1 1 1 0 PPP4R2 TFB6 PF17110.5 GBG83947.1 - 0.39 10.5 4.8 0.35 10.6 4.8 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Presenilin PF01080.17 GBG83947.1 - 0.41 9.3 1.4 0.32 9.7 1.4 1.0 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 GBG83947.1 - 0.82 9.4 2.4 0.7 9.6 2.4 1.1 1 0 0 1 1 1 0 Connexin gag-asp_proteas PF13975.6 GBG83948.1 - 0.0032 18.0 0.0 0.0075 16.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83948.1 - 0.018 15.7 0.0 0.037 14.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Macoilin PF09726.9 GBG83948.1 - 0.018 13.6 21.8 0.022 13.4 21.8 1.2 1 0 0 1 1 1 0 Macoilin family Asp_protease PF09668.10 GBG83948.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG83948.1 - 0.057 13.2 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Putative peptidase (DUF1758) SLC12 PF03522.15 GBG83948.1 - 0.77 8.7 35.5 1.3 7.9 35.5 1.5 1 0 0 1 1 1 0 Solute carrier family 12 Mitofilin PF09731.9 GBG83948.1 - 3.3 6.4 54.1 5.1 5.8 54.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4045 PF13254.6 GBG83948.1 - 4.2 6.9 43.2 8.3 5.9 43.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SOBP PF15279.6 GBG83948.1 - 6.1 7.4 17.6 9.2 6.8 17.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein TraV PF09676.10 GBG83948.1 - 8.6 7.4 36.2 0.035 15.1 12.3 2.5 1 1 1 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) DUF305 PF03713.13 GBG83950.1 - 1.1 9.4 5.9 4.3 7.5 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF305) zf-CCHC_6 PF15288.6 GBG83951.1 - 7e-05 22.6 0.5 0.00022 21.0 0.5 1.9 1 0 0 1 1 1 1 Zinc knuckle MutS_V PF00488.21 GBG83953.1 - 2.3e-26 93.0 0.0 5e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V Smr PF01713.21 GBG83953.1 - 1.4e-07 31.8 0.2 6.7e-07 29.6 0.2 2.3 1 0 0 1 1 1 1 Smr domain NPR3 PF03666.13 GBG83954.1 - 5.7 5.6 43.7 6.2 5.5 43.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 GBG83954.1 - 6.4 6.7 37.5 7.2 6.5 37.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF4746 PF15928.5 GBG83954.1 - 7.7 5.8 28.8 8.2 5.7 28.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Myb_DNA-bind_4 PF13837.6 GBG83955.1 - 0.00014 22.2 1.0 0.00027 21.2 1.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG83955.1 - 0.0067 16.5 0.0 0.022 14.8 0.2 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF3472 PF11958.8 GBG83955.1 - 0.038 14.5 0.8 0.066 13.7 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) DUF3273 PF11677.8 GBG83955.1 - 0.19 11.0 0.1 0.28 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) Troponin-I_N PF11636.8 GBG83955.1 - 0.25 11.3 2.2 0.66 10.0 2.2 1.7 1 0 0 1 1 1 0 Troponin I residues 1-32 GRP PF07172.11 GBG83955.1 - 0.28 11.9 12.9 0.87 10.3 1.2 2.5 2 0 0 2 2 2 0 Glycine rich protein family Neprosin PF03080.15 GBG83956.1 - 1.6e-71 240.2 3.2 2.7e-71 239.5 3.2 1.4 1 0 0 1 1 1 1 Neprosin Neprosin_AP PF14365.6 GBG83956.1 - 4.2e-16 59.5 2.0 3e-15 56.7 0.9 2.7 2 1 0 2 2 2 1 Neprosin activation peptide CSRNP_N PF16019.5 GBG83957.1 - 1.2 9.0 6.4 0.19 11.7 1.7 1.8 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus RNA_pol_3_Rpc31 PF11705.8 GBG83957.1 - 3.7 7.7 17.4 0.044 14.1 8.0 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 GBG83958.1 - 0.00021 20.8 18.3 0.00021 20.8 18.3 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG83958.1 - 0.0018 16.7 14.1 0.0018 16.7 14.1 1.1 1 0 0 1 1 1 1 CDC45-like protein TAF4 PF05236.14 GBG83958.1 - 0.012 15.4 12.2 0.014 15.1 12.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Nop14 PF04147.12 GBG83958.1 - 0.046 11.9 26.7 0.053 11.7 26.7 1.1 1 0 0 1 1 1 0 Nop14-like family SpoIIP PF07454.11 GBG83958.1 - 0.048 13.1 7.3 0.049 13.1 7.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) HNOBA PF07701.14 GBG83958.1 - 0.11 11.9 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Heme NO binding associated Sporozoite_P67 PF05642.11 GBG83958.1 - 0.13 10.3 11.1 0.16 10.0 11.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zip PF02535.22 GBG83958.1 - 0.18 11.0 5.9 0.18 11.0 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MDM1 PF15501.6 GBG83958.1 - 0.28 10.3 12.7 0.3 10.2 12.7 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 DUF2151 PF10221.9 GBG83958.1 - 0.69 8.4 4.1 0.57 8.7 4.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator K_channel_TID PF07941.11 GBG83958.1 - 0.75 10.3 14.7 2 8.9 14.7 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Presenilin PF01080.17 GBG83958.1 - 0.95 8.2 8.5 0.96 8.1 8.5 1.1 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 GBG83958.1 - 1.4 8.3 6.3 1.2 8.4 6.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LAP1C PF05609.12 GBG83958.1 - 1.5 7.8 8.8 1.3 8.0 8.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC27 PF09507.10 GBG83958.1 - 1.5 8.1 17.4 1.8 7.9 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 eIF-3c_N PF05470.12 GBG83958.1 - 1.7 6.9 8.7 1.8 6.8 8.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NPR3 PF03666.13 GBG83958.1 - 4.3 6.0 7.9 4.8 5.9 7.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Med17 PF10156.9 GBG83958.1 - 5.4 5.6 11.3 6.1 5.4 11.3 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Hid1 PF12722.7 GBG83958.1 - 5.8 4.9 6.5 6.1 4.8 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein gag-asp_proteas PF13975.6 GBG83959.1 - 3.9e-07 30.6 0.0 1e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG83959.1 - 4.5e-06 27.2 0.1 2.8e-05 24.7 0.0 2.3 3 0 0 3 3 3 1 Aspartyl protease DUF1758 PF05585.12 GBG83959.1 - 0.0025 17.6 0.0 0.0064 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF2862 PF11061.8 GBG83959.1 - 0.0087 15.9 0.2 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2862) Asp_protease PF09668.10 GBG83959.1 - 0.011 15.6 0.1 0.027 14.3 0.1 1.6 1 1 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG83959.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RNA_pol_3_Rpc31 PF11705.8 GBG83960.1 - 0.053 13.8 5.6 0.083 13.1 5.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 GBG83960.1 - 0.71 10.3 6.2 1.5 9.3 6.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.19 GBG83960.1 - 3 8.5 9.4 8.1 7.1 9.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein NOA36 PF06524.12 GBG83960.1 - 3.1 7.0 5.8 5 6.3 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 GBG83961.1 - 0.12 11.7 18.3 0.15 11.3 18.3 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG83961.1 - 1.3 8.3 15.5 1.5 8.2 15.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG83961.1 - 1.6 6.8 15.6 1.8 6.7 15.6 1.0 1 0 0 1 1 1 0 Nop14-like family MSA-2c PF12238.8 GBG83961.1 - 2.8 7.9 9.3 4 7.4 9.3 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c CDC45 PF02724.14 GBG83961.1 - 4.9 5.3 12.6 5.9 5.1 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 GBG83963.1 - 0.0001 21.7 1.2 0.0001 21.7 1.2 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter Otopetrin PF03189.13 GBG83963.1 - 0.0048 15.8 0.5 0.0063 15.4 0.5 1.4 1 0 0 1 1 1 1 Otopetrin DnaJ_CXXCXGXG PF00684.19 GBG83963.1 - 0.009 16.4 15.9 0.009 16.4 15.9 2.1 2 0 0 2 2 1 1 DnaJ central domain DDHD PF02862.17 GBG83963.1 - 0.0098 16.1 5.5 0.016 15.4 5.5 1.4 1 0 0 1 1 1 1 DDHD domain DUF2052 PF09747.9 GBG83963.1 - 0.48 10.5 25.8 0.68 10.0 25.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NPR3 PF03666.13 GBG83963.1 - 0.49 9.1 28.8 0.7 8.6 28.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Scs3p PF10261.9 GBG83963.1 - 0.66 9.4 7.0 1.6 8.2 7.0 1.7 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Hydin_ADK PF17213.3 GBG83963.1 - 0.74 10.1 12.6 1.5 9.0 12.6 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF913 PF06025.12 GBG83963.1 - 1.3 8.0 11.6 1.8 7.4 11.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Kei1 PF08552.11 GBG83963.1 - 1.3 8.9 6.5 3 7.7 6.5 1.6 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LAP1C PF05609.12 GBG83963.1 - 1.7 7.7 17.6 2.5 7.1 17.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2370 PF10176.9 GBG83963.1 - 1.8 8.2 5.2 2.9 7.5 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) CDC45 PF02724.14 GBG83963.1 - 2.3 6.4 24.1 3.2 5.9 24.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4050 PF13259.6 GBG83963.1 - 2.8 8.2 15.1 4.9 7.4 15.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) HCO3_cotransp PF00955.21 GBG83963.1 - 3.2 6.5 10.7 5.1 5.8 10.7 1.2 1 0 0 1 1 1 0 HCO3- transporter family RR_TM4-6 PF06459.12 GBG83963.1 - 3.6 7.4 33.8 6.2 6.6 33.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GBG83963.1 - 3.7 6.2 21.0 7.3 5.2 21.0 1.4 1 0 0 1 1 1 0 Presenilin DUF2126 PF09899.9 GBG83963.1 - 4.2 5.3 8.2 5.7 4.9 8.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Hid1 PF12722.7 GBG83963.1 - 5.8 4.9 15.7 7.4 4.6 15.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 GBG83963.1 - 6.2 7.3 16.7 8.8 6.8 16.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DAG_kinase_N PF14513.6 GBG83963.1 - 6.4 7.0 22.9 10 6.3 22.9 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Anti-TRAP PF15777.5 GBG83963.1 - 6.8 6.7 15.4 4 7.5 9.5 2.9 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Nucleoside_tran PF01733.18 GBG83963.1 - 7.5 5.8 9.2 19 4.5 9.2 1.7 1 0 0 1 1 1 0 Nucleoside transporter GREB1 PF15782.5 GBG83963.1 - 8.2 3.4 12.5 10 3.0 12.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RP-C_C PF11800.8 GBG83963.1 - 9.7 6.2 10.0 16 5.5 10.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Ribosomal_L11_N PF03946.14 GBG83964.1 - 1.8e-28 98.1 0.3 2.7e-28 97.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 GBG83964.1 - 4.9e-26 91.0 0.0 7.6e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain BUD22 PF09073.10 GBG83965.1 - 0.075 12.4 28.7 0.091 12.1 28.7 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG83965.1 - 1.6 8.1 37.1 2.3 7.6 37.1 1.2 1 0 0 1 1 1 0 SDA1 SRR1 PF07985.12 GBG83966.1 - 4.1e-06 26.7 0.1 8.8e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 SRR1 Rpr2 PF04032.16 GBG83967.1 - 0.0034 17.6 0.1 0.013 15.8 0.1 2.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Synaptobrevin PF00957.21 GBG83967.1 - 0.43 10.4 2.0 1.1 9.1 2.0 1.7 1 0 0 1 1 1 0 Synaptobrevin F-box-like PF12937.7 GBG83969.1 - 2.7e-05 24.0 0.7 0.0001 22.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box_5 PF18511.1 GBG83969.1 - 0.0048 16.4 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 GBG83969.1 - 0.031 14.2 0.0 0.031 14.2 0.0 2.6 2 0 0 2 2 2 0 F-box domain DUF659 PF04937.15 GBG83970.1 - 6.7e-15 55.3 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG83970.1 - 0.25 11.2 0.4 0.75 9.6 0.1 1.9 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG83971.1 - 9.9e-13 48.2 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG83971.1 - 0.043 13.6 0.1 0.095 12.5 0.1 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Myb_DNA-bind_4 PF13837.6 GBG83972.1 - 1.2e-07 32.0 3.4 3.3e-07 30.6 3.4 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain LapA_dom PF06305.11 GBG83972.1 - 0.0022 17.8 0.3 0.0041 16.9 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain MADF_DNA_bdg PF10545.9 GBG83972.1 - 0.0087 16.3 6.7 0.032 14.5 3.3 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like T2SSM PF04612.12 GBG83972.1 - 0.048 13.7 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M HemY_N PF07219.13 GBG83972.1 - 0.17 12.1 2.8 0.45 10.7 2.8 1.7 1 0 0 1 1 1 0 HemY protein N-terminus NfeD PF01957.18 GBG83972.1 - 0.4 11.1 1.5 0.53 10.7 0.4 1.7 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Herpes_LMP2 PF07415.11 GBG83972.1 - 0.5 9.1 1.0 1.6 7.4 0.1 1.9 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Myb_DNA-bind_4 PF13837.6 GBG83973.1 - 1.3e-08 35.1 2.9 1.3e-08 35.1 2.9 2.6 4 0 0 4 4 4 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG83973.1 - 6.1e-05 23.1 0.2 0.067 13.4 0.7 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG83973.1 - 0.00039 20.4 1.0 0.00087 19.3 1.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG83973.1 - 0.0057 17.0 3.7 0.0059 16.9 1.8 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG83973.1 - 0.031 14.5 1.9 0.081 13.2 1.9 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain PHD_3 PF13922.6 GBG83973.1 - 0.093 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Myb_DNA-bind_3 PF12776.7 GBG83973.1 - 0.12 13.4 1.9 0.33 12.0 1.9 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG83974.1 - 1e-23 83.7 0.1 2.6e-23 82.4 0.0 1.8 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG83974.1 - 3.8e-12 46.3 0.0 6.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG83974.1 - 0.12 12.0 0.9 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain RVT_1 PF00078.27 GBG83976.1 - 6.2e-32 110.9 0.0 9.1e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG83977.1 - 0.00054 19.9 1.6 0.00095 19.1 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle NOA36 PF06524.12 GBG83979.1 - 1.2 8.4 12.2 2.2 7.5 12.2 1.4 1 0 0 1 1 1 0 NOA36 protein Spore_coat_CotO PF14153.6 GBG83979.1 - 1.8 8.4 11.7 3.2 7.6 11.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF4407 PF14362.6 GBG83979.1 - 3.3 7.0 6.0 0.35 10.2 1.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF659 PF04937.15 GBG83980.1 - 1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CDC45 PF02724.14 GBG83980.1 - 0.1 10.9 7.7 0.14 10.4 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein GATA PF00320.27 GBG83982.1 - 3.5e-12 45.7 3.2 3.5e-12 45.7 3.2 2.2 3 0 0 3 3 3 1 GATA zinc finger RT_RNaseH_2 PF17919.1 GBG83983.1 - 2.6e-32 110.8 0.0 6.9e-16 58.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83983.1 - 1.3e-30 105.8 0.0 2.7e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG83983.1 - 2.9e-28 98.9 0.1 5.2e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG83983.1 - 2.4e-08 34.0 0.5 5.8e-08 32.7 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG83983.1 - 0.17 12.1 0.7 0.58 10.4 0.7 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF3824 PF12868.7 GBG83983.1 - 1.3 9.6 11.4 2.6 8.7 11.4 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DsrH PF04077.12 GBG83984.1 - 0.018 15.2 7.0 27 5.0 0.1 7.2 5 4 4 10 10 10 0 DsrH like protein Tox-REase-5 PF15648.6 GBG83984.1 - 0.031 14.8 6.2 0.42 11.2 0.6 4.0 4 1 0 4 4 4 0 Restriction endonuclease fold toxin 5 Peptidase_C48 PF02902.19 GBG83985.1 - 4.2e-07 30.0 1.3 4.2e-07 30.0 1.3 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF1896 PF08989.10 GBG83985.1 - 0.19 11.9 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) DUF659 PF04937.15 GBG83986.1 - 6.7e-17 61.7 0.0 1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Nop14 PF04147.12 GBG83986.1 - 6.8 4.8 9.5 11 4.1 9.5 1.2 1 0 0 1 1 1 0 Nop14-like family TMF_TATA_bd PF12325.8 GBG83989.1 - 0.025 14.8 0.1 0.025 14.8 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 GBG83989.1 - 0.11 11.8 13.2 0.81 9.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CLZ PF16526.5 GBG83989.1 - 1.7 9.1 9.0 0.23 11.8 0.4 3.4 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AIF-MLS PF14962.6 GBG83989.1 - 2.2 8.2 8.7 0.83 9.6 5.4 1.8 2 0 0 2 2 2 0 Mitochondria Localisation Sequence DUF1993 PF09351.10 GBG83989.1 - 2.3 8.3 8.2 11 6.2 3.7 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF1993) RVT_1 PF00078.27 GBG83992.1 - 2.6e-05 23.9 0.0 0.2 11.2 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) FAM76 PF16046.5 GBG83993.1 - 0.91 8.8 23.1 1.2 8.4 23.1 1.1 1 0 0 1 1 1 0 FAM76 protein Hydin_ADK PF17213.3 GBG83993.1 - 2.8 8.2 11.9 8.4 6.6 11.9 1.8 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain PvlArgDC PF01862.16 GBG83993.1 - 6.2 6.6 6.7 12 5.6 0.8 2.3 1 1 1 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) FUSC PF04632.12 GBG83993.1 - 6.8 5.1 13.2 9.5 4.6 13.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pkinase PF00069.25 GBG83995.1 - 2.7e-73 246.6 0.0 3.2e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG83995.1 - 1.7e-27 96.3 0.0 3.4e-27 95.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GBG83995.1 - 0.00042 19.4 0.0 0.0011 18.0 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 GBG83995.1 - 0.048 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 GBG83995.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.14 GBG83995.1 - 0.12 11.8 0.2 0.34 10.2 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4663 PF15668.5 GBG83995.1 - 0.66 9.0 3.0 0.96 8.4 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) RVT_1 PF00078.27 GBG83996.1 - 2.3e-05 24.0 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG83996.1 - 0.00024 21.7 0.0 0.0016 19.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG83996.1 - 0.00031 21.2 0.1 0.0015 19.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG83998.1 - 7.5e-23 80.5 0.0 2.4e-22 78.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG83998.1 - 4.8e-19 68.6 0.0 1.2e-18 67.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_2 PF13696.6 GBG83998.1 - 0.012 15.4 1.5 0.02 14.7 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG83998.1 - 0.015 15.6 0.3 0.047 14.0 0.3 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG83998.1 - 0.21 11.7 1.7 0.41 10.8 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG83998.1 - 0.23 11.3 0.9 0.61 10.0 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Motile_Sperm PF00635.26 GBG83999.1 - 1.1e-30 105.7 0.9 1.7e-29 101.8 1.1 2.2 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 GBG83999.1 - 0.019 15.2 0.1 0.054 13.7 0.1 1.7 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin GOLGA2L5 PF15070.6 GBG83999.1 - 0.019 13.6 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF222 PF02720.17 GBG83999.1 - 0.068 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF222) RVT_1 PF00078.27 GBG84002.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG84002.1 - 0.026 14.6 1.6 0.026 14.6 1.6 2.2 2 0 0 2 2 2 0 Zinc knuckle TetR_C_13 PF16925.5 GBG84002.1 - 0.16 11.9 0.2 0.52 10.3 0.2 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain gag-asp_proteas PF13975.6 GBG84003.1 - 0.00019 21.9 0.0 0.00038 21.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84003.1 - 0.0005 20.7 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RXLR PF16810.5 GBG84003.1 - 0.0013 19.2 2.1 0.16 12.4 0.4 2.3 2 0 0 2 2 2 2 RXLR phytopathogen effector protein, Avirulence activity Asp_protease PF09668.10 GBG84003.1 - 0.016 15.0 0.3 0.027 14.2 0.3 1.3 1 0 0 1 1 1 0 Aspartyl protease Surp PF01805.20 GBG84005.1 - 8e-09 35.4 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Surp module rve PF00665.26 GBG84006.1 - 9.4e-07 29.0 0.0 2.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG84006.1 - 0.074 13.7 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG84006.1 - 0.1 13.2 0.1 0.21 12.2 0.1 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG84008.1 - 1.4e-28 100.0 0.1 2.3e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84008.1 - 1.5e-28 99.1 0.0 3.1e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84008.1 - 3.7e-24 84.7 0.0 8.9e-13 48.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84009.1 - 2.9e-24 85.8 0.0 5.5e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2294 PF10057.9 GBG84009.1 - 0.0085 16.2 0.1 0.0085 16.2 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2294) RT_RNaseH_2 PF17919.1 GBG84010.1 - 5.9e-25 87.2 0.0 1.6e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84010.1 - 1.8e-24 86.0 0.2 1e-23 83.6 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84010.1 - 7.4e-05 22.9 0.1 0.00035 20.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG84010.1 - 0.00092 19.4 0.4 0.0061 16.8 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein FAM76 PF16046.5 GBG84010.1 - 1.9 7.8 7.6 3.7 6.8 7.6 1.4 1 0 0 1 1 1 0 FAM76 protein Spore_coat_CotO PF14153.6 GBG84010.1 - 2.9 7.8 9.0 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Spore coat protein CotO zf_CCCH_4 PF18345.1 GBG84012.1 - 0.00043 20.2 5.6 0.00082 19.3 5.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GBG84012.1 - 0.0033 17.3 2.7 0.0062 16.4 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GBG84012.1 - 0.0034 17.1 6.0 0.0078 16.0 6.0 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 GBG84012.1 - 0.0044 17.7 0.4 0.0044 17.7 0.4 2.5 2 0 0 2 2 2 1 Torus domain zf-CCCH_3 PF15663.5 GBG84012.1 - 0.13 12.5 0.2 0.4 10.9 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger containing family SRI PF08236.11 GBG84012.1 - 0.15 12.3 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain TFIIA PF03153.13 GBG84012.1 - 0.16 12.0 17.6 0.031 14.3 14.0 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Phage_lysozyme PF00959.19 GBG84013.1 - 0.0065 16.9 0.5 0.027 14.9 0.1 2.2 2 0 0 2 2 2 1 Phage lysozyme Dapper PF15268.6 GBG84013.1 - 7 5.4 15.1 11 4.8 15.1 1.1 1 0 0 1 1 1 0 Dapper RT_RNaseH PF17917.1 GBG84015.1 - 8.8e-25 87.0 0.0 1.3e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84015.1 - 7.7e-19 67.6 0.0 1.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG84016.1 - 3.7e-33 114.5 0.1 5.3e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG84016.1 - 0.00015 21.4 0.2 0.00029 20.6 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG84018.1 - 5.6e-15 55.5 0.2 2.9e-14 53.2 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG84018.1 - 0.0064 16.3 0.3 0.013 15.2 0.3 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SDA1 PF05285.12 GBG84018.1 - 5.1 6.4 9.3 8.6 5.7 9.3 1.3 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG84019.1 - 1.2e-25 90.3 0.0 2.1e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG84019.1 - 9.8e-10 38.3 0.0 2.3e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84019.1 - 3e-07 31.0 0.0 7.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG84019.1 - 4.5e-07 30.1 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG84019.1 - 9.5e-06 26.1 0.0 2.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG84019.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease TAF4 PF05236.14 GBG84019.1 - 0.74 9.5 10.2 1.3 8.7 10.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Integrase_H2C2 PF17921.1 GBG84021.1 - 5.3e-15 55.3 0.1 1.7e-14 53.6 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84021.1 - 2e-07 31.2 0.0 4.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG84021.1 - 1.3e-06 28.9 0.0 3.5e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84021.1 - 3.2e-05 24.5 0.0 0.00011 22.8 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG84021.1 - 4.3e-05 23.1 0.0 9.5e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG84021.1 - 0.0081 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG84021.1 - 0.0084 16.4 0.0 0.029 14.7 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG84022.1 - 1.8e-19 70.1 0.0 3e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG84022.1 - 1.2e-05 25.5 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain ATG2_CAD PF13329.6 GBG84022.1 - 0.035 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif DUF4097 PF13349.6 GBG84023.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative adhesin Pilus_CpaD PF09476.10 GBG84023.1 - 0.14 11.9 0.4 0.2 11.4 0.3 1.4 1 1 1 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) RT_RNaseH_2 PF17919.1 GBG84024.1 - 4.5e-30 103.7 0.0 1.4e-29 102.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84024.1 - 3.3e-29 102.0 0.6 1.5e-28 99.9 0.6 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84024.1 - 1.1e-24 86.7 0.0 2.6e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PNMA PF14893.6 GBG84024.1 - 0.017 14.5 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 PNMA DUF3453 PF11935.8 GBG84024.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Retrotrans_gag PF03732.17 GBG84024.1 - 0.41 10.9 0.1 0.41 10.9 0.1 2.9 5 1 0 5 5 5 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG84025.1 - 4.1e-16 59.2 0.0 1.2e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84025.1 - 5.5e-14 52.0 0.1 1.4e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_2 PF13696.6 GBG84025.1 - 0.0045 16.8 0.4 0.0089 15.8 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle rve PF00665.26 GBG84025.1 - 0.0058 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Choline_kin_N PF04428.14 GBG84025.1 - 0.014 15.1 0.1 7.5 6.3 0.0 2.9 2 0 0 2 2 2 0 Choline kinase N terminus rve_3 PF13683.6 GBG84025.1 - 0.093 12.5 0.0 0.35 10.7 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain zf-CCHC PF00098.23 GBG84025.1 - 0.19 11.8 1.9 0.42 10.8 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG84026.1 - 0.044 13.5 0.3 0.11 12.2 0.3 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RT_RNaseH_2 PF17919.1 GBG84027.1 - 7.8e-34 115.7 0.1 3e-31 107.4 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84027.1 - 5.1e-26 91.0 0.0 1.5e-25 89.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84027.1 - 2.1e-17 63.4 0.3 1e-10 41.5 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG84027.1 - 0.0041 16.8 6.5 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 Phage capsid scaffolding protein (GPO) serine peptidase Tom22 PF04281.13 GBG84027.1 - 0.0089 15.8 0.4 0.018 14.8 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Mu-like_Pro PF10123.9 GBG84027.1 - 0.14 11.7 6.3 0.25 10.9 6.3 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein YabA PF06156.13 GBG84027.1 - 0.36 11.5 0.0 0.36 11.5 0.0 2.6 3 0 0 3 3 3 0 Initiation control protein YabA RPAP3_C PF13877.6 GBG84027.1 - 0.44 11.1 2.5 1.8 9.2 0.0 3.0 3 1 0 3 3 3 0 Potential Monad-binding region of RPAP3 FERM_f0 PF16511.5 GBG84028.1 - 0.00018 21.7 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM Rossmann-like PF10727.9 GBG84028.1 - 0.0042 16.9 0.0 3.7 7.4 0.0 2.2 2 0 0 2 2 2 2 Rossmann-like domain DUF3562 PF12085.8 GBG84028.1 - 0.053 13.1 0.0 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) RT_RNaseH_2 PF17919.1 GBG84029.1 - 7.7e-35 118.9 0.0 2.4e-34 117.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84029.1 - 2.2e-31 108.2 0.1 4.7e-31 107.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84029.1 - 5e-23 81.8 0.1 9.4e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG84029.1 - 3.2e-16 59.6 0.0 2.6e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG84029.1 - 2.4e-10 40.3 0.0 6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG84029.1 - 0.0051 16.6 0.1 0.0093 15.7 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease NAAA-beta PF15508.6 GBG84029.1 - 0.031 14.6 0.1 0.46 10.8 0.0 2.8 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase RVT_1 PF00078.27 GBG84031.1 - 3.2e-24 85.7 0.0 5.4e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CPT PF07931.12 GBG84031.1 - 0.11 12.4 0.0 6.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF928 PF06051.12 GBG84032.1 - 0.054 13.3 0.9 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) Chorion_3 PF05387.11 GBG84035.1 - 0.39 10.3 4.4 0.51 9.9 4.4 1.1 1 0 0 1 1 1 0 Chorion family 3 RT_RNaseH_2 PF17919.1 GBG84036.1 - 9.7e-31 105.8 0.0 1.8e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84036.1 - 9.2e-29 99.8 0.2 1.8e-28 98.9 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG84036.1 - 1.2e-05 25.9 0.0 3.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84036.1 - 0.00028 21.4 0.0 0.0011 19.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG84036.1 - 0.0011 19.2 0.1 0.004 17.4 0.1 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84036.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 GBG84036.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase rve PF00665.26 GBG84036.1 - 0.0066 16.6 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG84036.1 - 0.089 12.5 0.4 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RT_RNaseH_2 PF17919.1 GBG84037.1 - 1.1e-26 92.8 0.0 3.7e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chorein_N PF12624.7 GBG84037.1 - 6.7e-18 64.9 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 RT_RNaseH PF17917.1 GBG84037.1 - 3.5e-17 62.6 0.0 1.1e-16 61.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG84037.1 - 0.0018 18.5 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG84037.1 - 0.0072 16.1 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG84039.1 - 9.6e-16 58.1 0.0 1.6e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG84039.1 - 0.00053 19.7 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.20 GBG84039.1 - 0.12 12.7 0.0 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease RelE PF06296.12 GBG84040.1 - 0.0014 18.8 0.1 0.0026 17.9 0.1 1.3 1 0 0 1 1 1 1 RelE toxin of RelE / RelB toxin-antitoxin system gag-asp_proteas PF13975.6 GBG84042.1 - 0.00017 22.1 0.0 0.00046 20.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84042.1 - 0.00064 20.3 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG84042.1 - 0.00067 19.9 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Rx_N PF18052.1 GBG84042.1 - 0.06 13.6 1.0 9.4 6.6 0.0 3.2 3 0 0 3 3 3 0 Rx N-terminal domain Retrotrans_gag PF03732.17 GBG84042.1 - 0.077 13.3 0.1 0.27 11.5 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG84042.1 - 0.19 11.5 0.0 0.61 9.9 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG84044.1 - 2.8e-43 148.0 0.9 2.6e-31 108.9 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84044.1 - 8.7e-40 134.8 0.2 3.6e-32 110.4 0.1 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84044.1 - 1.6e-30 105.5 0.3 2.7e-29 101.5 0.1 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84044.1 - 1.7e-17 63.3 0.1 3.9e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84044.1 - 1.4e-06 28.5 0.0 5.1e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG84044.1 - 1.4e-05 25.3 0.7 0.04 14.2 0.0 3.1 2 0 0 2 2 2 2 Retrotransposon gag protein Virul_fac_BrkB PF03631.15 GBG84044.1 - 2.9e-05 23.8 4.6 0.028 14.0 7.0 2.3 2 0 0 2 2 2 1 Virulence factor BrkB WD40 PF00400.32 GBG84044.1 - 6.2e-05 23.7 6.6 0.024 15.5 1.5 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat zf-H2C2 PF09337.10 GBG84044.1 - 0.011 15.9 0.0 0.041 14.1 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger DUF1079 PF06435.11 GBG84044.1 - 0.24 11.6 1.3 16 5.9 0.0 3.1 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) DUF5095 PF17016.5 GBG84044.1 - 0.37 10.4 2.4 12 5.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) RT_RNaseH_2 PF17919.1 GBG84045.1 - 1.4e-56 188.7 0.0 1.8e-28 98.5 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84045.1 - 7.6e-53 177.2 0.0 2.7e-25 88.7 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84045.1 - 1.2e-22 80.3 0.2 3.5e-15 56.2 0.1 2.9 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG84045.1 - 2.2e-19 69.3 0.1 5.3e-19 68.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain WD40 PF00400.32 GBG84045.1 - 4.8e-08 33.5 0.6 0.0019 19.0 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Retrotrans_gag PF03732.17 GBG84045.1 - 0.001 19.3 3.2 9.9 6.5 0.0 4.7 4 0 0 4 4 4 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG84045.1 - 0.0031 17.7 0.0 0.0096 16.1 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger TMF_TATA_bd PF12325.8 GBG84045.1 - 0.0073 16.5 0.6 0.0073 16.5 0.6 3.3 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF4784 PF16023.5 GBG84045.1 - 0.0074 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4784) DUF1564 PF07600.11 GBG84045.1 - 0.051 13.3 0.2 0.4 10.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) PHM7_cyt PF14703.6 GBG84045.1 - 0.65 10.2 2.9 0.74 10.0 0.4 2.4 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4407 PF14362.6 GBG84045.1 - 5.4 6.3 8.1 1.7 7.9 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG84047.1 - 3.1e-24 85.7 0.2 5e-24 85.0 0.2 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG84048.1 - 2.5e-30 105.7 0.0 4.4e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84048.1 - 6.6e-30 103.1 0.0 1.8e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84048.1 - 4.9e-29 100.7 0.0 1.1e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG84048.1 - 1.1e-05 25.2 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84048.1 - 0.0049 17.5 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG84048.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG84048.1 - 0.033 14.7 0.0 0.078 13.5 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Phage_GPO PF05929.11 GBG84048.1 - 2.7 7.5 5.2 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG84049.1 - 3.8e-31 108.3 0.0 6.6e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84049.1 - 1.3e-30 105.4 0.0 3.8e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84049.1 - 1.2e-29 102.7 0.0 2.3e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG84049.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG84050.1 - 1e-60 205.0 0.1 1.1e-33 116.6 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84050.1 - 2.5e-53 178.3 0.0 2.8e-27 94.7 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84050.1 - 3.6e-49 165.4 0.0 1.4e-26 92.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84050.1 - 2e-35 120.7 4.3 4.5e-17 61.9 0.6 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG84050.1 - 3.9e-14 52.9 0.0 1.5e-13 51.0 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG84050.1 - 1.3e-12 47.6 0.0 9.7e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84050.1 - 6.1e-07 30.0 0.0 0.00021 21.8 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84050.1 - 2.9e-05 24.5 0.0 0.0018 18.8 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG84050.1 - 0.0012 19.1 0.2 0.23 11.7 0.0 3.7 3 0 0 3 3 3 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG84050.1 - 0.0033 17.6 0.2 4.8 7.5 0.1 2.8 2 0 0 2 2 2 2 H2C2 zinc finger DUF1758 PF05585.12 GBG84050.1 - 0.0043 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG84050.1 - 0.15 11.9 0.0 6.7 6.5 0.0 3.0 3 0 0 3 3 3 0 Aspartyl protease DUF935 PF06074.12 GBG84051.1 - 0.098 11.4 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) RT_RNaseH_2 PF17919.1 GBG84052.1 - 2.9e-25 88.2 0.1 6.4e-25 87.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ncstrn_small PF18266.1 GBG84052.1 - 8.7e-24 84.4 0.0 1.6e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Nicastrin small lobe RT_RNaseH PF17917.1 GBG84052.1 - 6.3e-12 45.7 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RNA_pol_3_Rpc31 PF11705.8 GBG84052.1 - 1.4e-05 25.4 2.3 1.4e-05 25.4 2.3 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 GBG84052.1 - 0.00025 21.2 0.6 0.0005 20.2 0.6 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 GBG84052.1 - 1.4 8.3 11.3 2.8 7.3 11.3 1.4 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 GBG84052.1 - 1.6 8.0 5.8 3 7.1 5.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NOA36 PF06524.12 GBG84052.1 - 1.6 7.9 17.4 4.1 6.6 17.4 1.6 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GBG84052.1 - 2 6.6 10.4 3.2 5.9 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 GBG84052.1 - 2 8.1 5.7 5 6.8 5.7 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop14 PF04147.12 GBG84052.1 - 2.6 6.1 13.3 4.2 5.4 13.3 1.2 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 GBG84052.1 - 2.7 7.6 10.5 0.89 9.2 7.1 1.9 2 0 0 2 2 2 0 FAM176 family CobT PF06213.12 GBG84052.1 - 4.2 6.7 12.0 8.5 5.7 12.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RT_RNaseH_2 PF17919.1 GBG84053.1 - 9.1e-27 93.0 0.0 1.6e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84053.1 - 2e-24 85.9 0.0 3.8e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84053.1 - 3.4e-21 75.8 0.1 5.4e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG84053.1 - 0.95 7.6 9.6 1.3 7.2 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG84053.1 - 1.2 7.4 9.1 1.6 6.9 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 GBG84054.1 - 1e-72 244.7 0.0 1.6e-72 244.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 GBG84054.1 - 2e-31 105.1 4.2 1.8e-07 30.2 0.3 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.17 GBG84054.1 - 1.3e-26 93.5 0.0 2.1e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 GBG84054.1 - 4.2e-24 82.4 2.8 7.6e-07 28.6 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 GBG84054.1 - 5.1e-24 84.5 1.7 1.2e-12 48.1 0.5 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG84054.1 - 8.5e-21 72.5 4.1 1.7e-05 24.1 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GBG84054.1 - 2.5e-17 62.4 4.4 0.00026 20.8 0.0 4.5 3 1 1 4 4 4 4 EF-hand domain pair Kdo PF06293.14 GBG84054.1 - 6.1e-06 25.7 0.0 1.6e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 GBG84054.1 - 7.4e-05 22.6 2.0 0.17 11.8 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GBG84054.1 - 0.0003 21.1 0.7 0.26 11.6 0.1 2.7 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 GBG84054.1 - 0.00069 19.7 0.2 0.14 12.3 0.1 2.8 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.6 GBG84054.1 - 0.0012 19.1 0.1 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain Kinase-like PF14531.6 GBG84054.1 - 0.0012 18.2 0.0 0.03 13.7 0.0 2.6 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 GBG84054.1 - 0.0051 16.8 0.0 1.2 9.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_11 PF08976.11 GBG84054.1 - 0.035 15.0 0.0 3.9 8.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain Pkinase PF00069.25 GBG84055.1 - 1e-72 244.7 0.0 1.5e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 GBG84055.1 - 1.9e-31 105.3 4.2 1.7e-07 30.3 0.3 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.17 GBG84055.1 - 1e-26 93.8 0.0 2e-26 92.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_6 PF13405.6 GBG84055.1 - 3.8e-24 82.5 2.8 7.5e-07 28.6 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 GBG84055.1 - 4.9e-24 84.6 1.7 1.2e-12 48.1 0.5 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG84055.1 - 7.7e-21 72.6 4.1 1.7e-05 24.1 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GBG84055.1 - 4.2e-17 61.7 5.1 0.00026 20.8 0.0 4.5 3 1 1 4 4 4 4 EF-hand domain pair Kdo PF06293.14 GBG84055.1 - 6.1e-06 25.7 0.0 1.6e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 GBG84055.1 - 7.6e-05 22.6 2.2 0.17 11.8 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GBG84055.1 - 0.00026 21.3 0.7 0.24 11.7 0.1 2.7 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 GBG84055.1 - 0.00065 19.7 0.2 0.13 12.4 0.1 2.8 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Kinase-like PF14531.6 GBG84055.1 - 0.00092 18.6 0.0 0.029 13.7 0.0 2.8 2 1 0 2 2 2 1 Kinase-like EF-hand_9 PF14658.6 GBG84055.1 - 0.0011 19.2 0.1 0.098 13.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain APH PF01636.23 GBG84055.1 - 0.0049 16.8 0.0 1.2 9.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_11 PF08976.11 GBG84055.1 - 0.034 15.0 0.0 3.2 8.7 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain DUF5580 PF17743.1 GBG84055.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) RVT_1 PF00078.27 GBG84058.1 - 1.2e-09 38.0 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG84058.1 - 1.6e-05 25.5 0.2 3.8e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Calreticulin PF00262.18 GBG84059.1 - 9.8e-141 468.9 4.7 1.2e-140 468.5 4.7 1.1 1 0 0 1 1 1 1 Calreticulin family DUF2620 PF10941.8 GBG84059.1 - 0.36 11.0 2.8 0.78 9.9 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF2620 RVT_1 PF00078.27 GBG84060.1 - 2.6e-19 69.6 0.0 4.7e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84060.1 - 2.5e-09 37.7 0.0 5.8e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84060.1 - 9e-09 35.8 0.0 1.9e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84060.1 - 6.9e-08 32.3 0.0 1.9e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84060.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG84060.1 - 0.006 16.8 1.9 0.0074 16.5 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Arb2 PF09757.9 GBG84061.1 - 0.00032 19.9 0.0 0.00057 19.1 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Abhydrolase_6 PF12697.7 GBG84061.1 - 0.0012 19.5 0.5 0.0018 18.9 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF659 PF04937.15 GBG84062.1 - 1.4e-34 119.2 0.1 2.4e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG84062.1 - 0.00025 20.8 0.2 0.0012 18.5 0.2 2.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nop53 PF07767.11 GBG84063.1 - 0.18 11.2 25.9 0.41 10.0 25.9 1.6 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GBG84063.1 - 1.6 6.9 23.9 4.4 5.5 23.9 1.7 1 0 0 1 1 1 0 CDC45-like protein Na_trans_assoc PF06512.13 GBG84063.1 - 2.8 8.1 19.8 0.36 11.1 14.8 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated RVT_1 PF00078.27 GBG84066.1 - 8.1e-16 58.2 0.0 1.4e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sporozoite_P67 PF05642.11 GBG84066.1 - 0.0072 14.5 3.0 0.011 13.9 3.0 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Macoilin PF09726.9 GBG84066.1 - 1.4 7.4 7.0 2.6 6.5 7.0 1.4 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 GBG84066.1 - 3.6 5.6 4.9 5.8 4.9 4.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RVT_1 PF00078.27 GBG84067.1 - 8.3e-24 84.3 0.1 1.5e-23 83.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) G8 PF10162.9 GBG84067.1 - 2.2e-12 47.1 0.1 7.1e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 G8 domain ZapB PF06005.12 GBG84067.1 - 0.012 16.1 0.2 0.012 16.1 0.2 3.5 3 1 0 3 3 3 0 Cell division protein ZapB gag-asp_proteas PF13975.6 GBG84067.1 - 0.015 15.9 0.0 0.048 14.2 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84067.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84067.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG84067.1 - 0.13 12.6 3.4 0.13 12.5 0.3 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG84069.1 - 3.5e-30 105.2 0.1 5.4e-30 104.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NIF PF03031.18 GBG84069.1 - 2.5e-11 43.6 0.3 5.9e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase gag-asp_proteas PF13975.6 GBG84069.1 - 5.6e-08 33.2 0.0 1.4e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84069.1 - 1.4e-07 32.0 0.0 3.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG84069.1 - 4e-06 26.6 0.0 9.5e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG84069.1 - 5.7e-06 26.2 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease CDH1_2_SANT_HL1 PF18375.1 GBG84069.1 - 0.056 14.1 2.0 0.073 13.8 0.1 2.1 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 NIF PF03031.18 GBG84070.1 - 4.9e-21 75.1 0.0 9.7e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase GET2 PF08690.10 GBG84070.1 - 5.2 6.6 5.5 7.5 6.1 5.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Serglycin PF04360.12 GBG84071.1 - 0.012 15.5 1.1 0.018 15.0 1.1 1.2 1 0 0 1 1 1 0 Serglycin GRP PF07172.11 GBG84071.1 - 0.1 13.3 5.3 0.16 12.7 5.3 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF4510 PF14971.6 GBG84072.1 - 0.18 12.2 0.0 0.27 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) EF-hand_1 PF00036.32 GBG84073.1 - 3.6e-22 76.2 0.0 8.2e-07 28.1 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GBG84073.1 - 2.1e-19 67.7 0.1 2.3e-05 24.0 0.0 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 GBG84073.1 - 1.4e-18 67.1 0.3 1.3e-08 35.2 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG84073.1 - 3.6e-13 48.4 0.0 0.00012 21.4 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 GBG84073.1 - 2.5e-11 43.2 0.4 4.6e-06 26.4 0.0 4.4 4 1 1 5 5 5 2 EF-hand domain pair Caleosin PF05042.13 GBG84073.1 - 0.00023 21.2 0.4 0.05 13.5 0.0 3.4 2 1 2 4 4 4 1 Caleosin related protein EF-hand_9 PF14658.6 GBG84073.1 - 0.00063 20.0 0.1 0.054 13.8 0.0 3.3 4 0 0 4 4 4 1 EF-hand domain Toprim PF01751.22 GBG84073.1 - 0.19 12.0 0.0 1.2 9.4 0.0 2.1 1 1 1 2 2 2 0 Toprim domain TTL PF03133.15 GBG84075.1 - 1.7e-34 119.3 0.0 3.7e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family RT_RNaseH_2 PF17919.1 GBG84075.1 - 1.8e-27 95.3 0.0 3.7e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84075.1 - 2.5e-24 85.6 0.1 5e-24 84.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84075.1 - 5.5e-15 55.6 0.0 1.9e-14 53.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG84075.1 - 2.2e-08 33.9 0.0 4.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_3_Rpc31 PF11705.8 GBG84075.1 - 0.81 9.9 11.5 0.012 15.9 3.6 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Radial_spoke PF04712.12 GBG84075.1 - 4.4 6.1 9.8 8.9 5.1 9.8 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein FAM176 PF14851.6 GBG84075.1 - 4.7 6.9 10.5 5.6 6.6 5.3 2.7 2 0 0 2 2 2 0 FAM176 family Glyco_transf_34 PF05637.12 GBG84076.1 - 1.7e-23 83.6 0.1 1.2e-22 80.9 0.1 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 GBG84076.1 - 0.004 17.2 1.7 0.01 15.9 1.7 1.6 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase TFIIF_alpha PF05793.12 GBG84077.1 - 0.019 13.6 8.0 0.024 13.2 8.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GBG84077.1 - 1.7 6.9 7.9 2.1 6.6 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Pep1_7 PF17232.2 GBG84077.1 - 2.4 8.7 6.3 0.88 10.1 2.7 2.1 2 0 0 2 2 2 0 Elicitor peptide 1-7 Glyco_transf_34 PF05637.12 GBG84078.1 - 5.6e-23 81.9 0.1 2.2e-22 80.0 0.1 1.8 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 GBG84078.1 - 0.0033 17.4 2.3 0.01 15.8 2.3 1.7 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 GBG84080.1 - 0.00012 21.9 0.1 0.0002 21.2 0.1 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Myb_DNA-bind_4 PF13837.6 GBG84081.1 - 1.5e-10 41.3 0.9 3.7e-10 40.0 0.9 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG84081.1 - 0.023 15.0 0.3 0.046 14.0 0.3 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like gag-asp_proteas PF13975.6 GBG84082.1 - 0.0059 17.1 0.0 0.018 15.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84082.1 - 0.021 15.4 0.0 0.048 14.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Prominin PF05478.11 GBG84082.1 - 0.34 8.8 1.2 0.47 8.4 1.2 1.2 1 0 0 1 1 1 0 Prominin Myb_DNA-bind_4 PF13837.6 GBG84083.1 - 0.00014 22.2 0.2 0.00027 21.3 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG84083.1 - 0.0012 18.9 1.1 0.0023 18.0 1.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG84083.1 - 0.026 14.7 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sporozoite_P67 PF05642.11 GBG84083.1 - 0.76 7.8 5.4 0.091 10.8 0.3 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RT_RNaseH PF17917.1 GBG84084.1 - 9.3e-22 77.3 0.0 2.6e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84084.1 - 9.9e-21 73.7 0.0 2.2e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84084.1 - 1.1e-17 63.9 1.0 2.5e-17 62.7 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG84084.1 - 9.4e-16 58.1 0.0 2.4e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain FAM153 PF15722.5 GBG84086.1 - 0.05 14.0 0.1 0.11 12.8 0.1 1.7 1 1 0 1 1 1 0 FAM153 family RVT_1 PF00078.27 GBG84087.1 - 0.06 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_34 PF05637.12 GBG84088.1 - 5.3e-22 78.7 0.6 3.5e-21 76.0 0.6 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family APG17 PF04108.12 GBG84089.1 - 0.076 12.1 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 HhH-GPD PF00730.25 GBG84090.1 - 0.00019 21.9 0.1 0.23 11.9 0.0 2.6 2 0 0 2 2 2 2 HhH-GPD superfamily base excision DNA repair protein SAP PF02037.27 GBG84090.1 - 0.0014 18.4 0.2 2.1 8.2 0.1 2.8 2 0 0 2 2 2 2 SAP domain E1_UFD PF09358.10 GBG84090.1 - 0.0031 18.2 0.3 4.6 8.0 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin fold domain DWNN PF08783.11 GBG84090.1 - 0.01 16.1 5.0 2 8.8 0.4 2.5 2 0 0 2 2 2 2 DWNN domain DUF4046 PF13255.6 GBG84090.1 - 0.04 14.5 0.0 6.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4046) DUF2385 PF09539.10 GBG84090.1 - 0.12 12.9 0.1 35 5.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) TSP_NTD PF17804.1 GBG84090.1 - 0.14 12.4 1.4 0.4 10.9 0.1 2.3 2 0 0 2 2 2 0 Tail specific protease N-terminal domain Kisspeptin PF15152.6 GBG84090.1 - 0.16 12.8 5.7 8.2 7.3 0.1 3.2 2 1 0 2 2 2 0 Kisspeptin MRP-S25 PF13741.6 GBG84090.1 - 0.29 10.6 9.6 0.2 11.2 2.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S25 zf-CCHC PF00098.23 GBG84091.1 - 2.6e-06 27.3 2.9 9.1e-06 25.5 2.9 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG84091.1 - 0.0027 17.5 3.3 0.022 14.6 0.6 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG84091.1 - 0.13 12.3 2.7 0.24 11.4 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle Bcl-2_BAD PF10514.9 GBG84091.1 - 0.25 11.8 11.2 0.26 11.7 0.0 2.9 3 0 0 3 3 3 0 Pro-apoptotic Bcl-2 protein, BAD Sec62 PF03839.16 GBG84091.1 - 6.8 6.1 10.1 13 5.3 10.1 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 BT1 PF03092.16 GBG84091.1 - 7.8 4.6 4.6 11 4.1 4.6 1.1 1 0 0 1 1 1 0 BT1 family Chlam_PMP PF02415.17 GBG84093.1 - 0.00032 21.0 35.5 0.38 11.3 0.1 7.7 8 0 0 8 8 8 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Tfb4 PF03850.14 GBG84096.1 - 0.56 9.7 2.0 0.74 9.2 2.0 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 DDRGK PF09756.9 GBG84096.1 - 1.5 8.4 25.7 4.3 6.9 25.7 1.7 1 0 0 1 1 1 0 DDRGK domain MCM3AP_GANP PF16769.5 GBG84096.1 - 2.2 6.4 10.5 3.5 5.8 10.5 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP UPF0242 PF06785.11 GBG84096.1 - 7.6 6.6 13.5 14 5.7 13.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ALMT PF11744.8 GBG84096.1 - 9.3 4.9 7.4 12 4.6 7.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Chlam_PMP PF02415.17 GBG84097.1 - 2e-05 24.8 18.8 3.4 8.3 1.0 6.6 6 0 0 6 6 6 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 GBG84097.1 - 4.7e-05 23.3 7.8 0.0015 18.4 7.8 2.3 1 1 1 2 2 2 2 Right handed beta helix region PhyH PF05721.13 GBG84097.1 - 0.19 12.0 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Beta_helix PF13229.6 GBG84098.1 - 4.9e-08 33.0 14.6 1.6e-07 31.3 14.1 1.9 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG84098.1 - 1.4e-06 28.4 35.1 0.1 13.2 0.2 7.6 7 0 0 7 7 7 6 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NosD PF05048.13 GBG84098.1 - 0.11 11.8 2.8 0.25 10.6 2.6 1.8 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF659 PF04937.15 GBG84099.1 - 1.7e-09 37.8 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG84100.1 - 1.9e-31 109.3 0.3 2.9e-31 108.7 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG84100.1 - 1.2e-08 34.8 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84100.1 - 0.00033 21.3 0.0 0.00082 20.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG84100.1 - 0.0034 17.2 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG84100.1 - 0.0096 16.5 0.0 0.03 14.9 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG84100.1 - 0.088 12.6 0.0 0.46 10.3 0.0 2.2 2 1 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG84103.1 - 2e-31 108.0 0.1 3.9e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84103.1 - 2.8e-21 75.8 0.0 5.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG84103.1 - 1.9e-08 34.0 1.2 3.2e-08 33.3 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG84103.1 - 0.02 14.7 2.7 0.034 14.0 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 GBG84105.1 - 3e-13 50.0 0.0 8.6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG84107.1 - 2.1e-07 30.6 0.1 3.4e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ldl_recept_a PF00057.18 GBG84108.1 - 3e-71 235.3 167.9 4.2e-09 36.5 7.3 13.1 11 1 1 12 12 12 12 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 GBG84109.1 - 1.5e-49 165.9 157.0 3.6e-08 33.5 5.8 12.5 13 0 0 13 13 13 10 Low-density lipoprotein receptor domain class A Histone PF00125.24 GBG84110.1 - 1.4e-05 25.5 1.7 2.9e-05 24.4 1.7 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RVT_1 PF00078.27 GBG84112.1 - 8.5e-29 100.6 0.1 1.5e-28 99.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84112.1 - 5.2e-25 87.4 0.0 1.4e-24 86.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84112.1 - 3.1e-16 59.6 0.0 7.9e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG84112.1 - 0.0033 16.6 0.6 0.52 9.4 0.0 2.8 2 1 1 3 3 3 1 Autophagy protein Apg17 Retrotrans_gag PF03732.17 GBG84112.1 - 0.02 15.1 0.4 0.15 12.4 0.4 2.6 1 0 0 1 1 1 0 Retrotransposon gag protein Herpes_BLRF2 PF05812.12 GBG84112.1 - 0.06 13.5 0.5 0.18 11.9 0.5 1.8 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein RVP_2 PF08284.11 GBG84112.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease CCSAP PF15748.5 GBG84112.1 - 1 9.5 4.5 2.9 8.0 1.5 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Myb_DNA-bind_4 PF13837.6 GBG84113.1 - 6.3e-06 26.5 5.8 1.3e-05 25.5 5.8 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG84113.1 - 0.0026 18.1 1.9 0.0046 17.2 1.9 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3693 PF12472.8 GBG84113.1 - 0.12 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Phage related protein Ldl_recept_a PF00057.18 GBG84114.1 - 1.3e-56 188.5 177.2 1.8e-08 34.4 6.6 13.3 14 0 0 14 14 14 12 Low-density lipoprotein receptor domain class A Hexapep PF00132.24 GBG84114.1 - 0.00033 20.3 5.3 0.095 12.5 0.8 3.1 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Myb_DNA-bind_4 PF13837.6 GBG84115.1 - 2.1e-08 34.4 1.8 2.4e-08 34.3 0.4 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG84115.1 - 0.00048 20.1 2.0 0.0016 18.4 2.0 2.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG84116.1 - 9.3e-32 109.9 0.0 2.2e-31 108.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84116.1 - 9.6e-17 61.3 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84116.1 - 0.002 17.8 0.1 0.3 10.7 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain HTH_48 PF17906.1 GBG84116.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 HTH domain in Mos1 transposase BUD22 PF09073.10 GBG84117.1 - 8.5e-05 22.1 15.3 8.5e-05 22.1 15.3 1.5 2 0 0 2 2 2 1 BUD22 Plasmodium_Vir PF05795.11 GBG84117.1 - 0.0021 17.5 0.3 0.0047 16.4 0.3 1.5 1 0 0 1 1 1 1 Plasmodium vivax Vir protein SprA-related PF12118.8 GBG84117.1 - 0.011 14.9 5.9 0.019 14.1 5.9 1.4 1 0 0 1 1 1 0 SprA-related family DDHD PF02862.17 GBG84117.1 - 0.13 12.4 0.4 0.29 11.3 0.2 1.6 2 0 0 2 2 1 0 DDHD domain DUF1835 PF08874.10 GBG84117.1 - 0.14 12.4 4.7 0.28 11.4 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) PA26 PF04636.13 GBG84117.1 - 0.19 10.6 1.2 0.27 10.1 1.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.12 GBG84117.1 - 0.26 11.1 17.2 0.47 10.2 17.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2151 PF10221.9 GBG84117.1 - 0.29 9.7 3.9 0.43 9.1 3.9 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 GBG84117.1 - 0.32 10.2 3.4 0.59 9.3 3.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.8 GBG84117.1 - 0.33 11.0 3.5 0.79 9.8 3.5 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region SpoIIP PF07454.11 GBG84117.1 - 0.33 10.4 10.3 0.53 9.7 10.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FYDLN_acid PF09538.10 GBG84117.1 - 0.56 10.9 25.4 1.4 9.6 25.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CPSF100_C PF13299.6 GBG84117.1 - 0.66 10.1 9.6 1.4 9.0 9.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2052 PF09747.9 GBG84117.1 - 1 9.5 27.9 2.4 8.2 27.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Mpp10 PF04006.12 GBG84117.1 - 1.1 7.7 33.7 1.5 7.1 33.7 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 GBG84117.1 - 1.2 7.6 38.7 2.1 6.8 38.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.14 GBG84117.1 - 1.5 8.6 20.5 3.4 7.4 20.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein VIR_N PF15912.5 GBG84117.1 - 1.8 8.1 17.1 3.1 7.3 17.1 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Merozoite_SPAM PF07133.11 GBG84117.1 - 3.4 7.6 50.4 6.4 6.7 50.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RNA_polI_A34 PF08208.11 GBG84117.1 - 6.9 6.7 22.1 14 5.7 22.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RT_RNaseH_2 PF17919.1 GBG84121.1 - 1.8e-21 76.0 0.1 1.5e-20 73.1 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84121.1 - 1.1e-19 70.7 0.0 2.3e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84121.1 - 4.1e-19 68.4 0.1 8e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG84121.1 - 5.1e-15 55.6 0.1 1.3e-14 54.3 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84121.1 - 5.2e-08 33.4 0.0 1.3e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG84121.1 - 3.3e-07 30.2 0.0 8.6e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG84121.1 - 3.2e-06 27.3 0.0 8.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG84121.1 - 2.7e-05 24.6 0.0 9.2e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG84121.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease MCM3AP_GANP PF16769.5 GBG84122.1 - 2.6 6.2 6.3 3.1 5.9 6.3 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP RT_RNaseH_2 PF17919.1 GBG84126.1 - 1.3e-28 99.0 0.0 2.6e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84126.1 - 1.3e-15 57.6 0.0 2.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84126.1 - 1.2e-14 54.3 0.0 1.9e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84127.1 - 7e-24 83.8 0.0 1.2e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84127.1 - 7.7e-21 74.4 0.0 1.3e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG84127.1 - 0.1 12.0 10.5 0.16 11.4 10.5 1.3 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 GBG84127.1 - 2.5 7.1 5.9 4.1 6.4 5.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG84127.1 - 3.7 5.6 16.8 4.9 5.2 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG84127.1 - 3.7 6.8 17.5 6.2 6.0 17.5 1.3 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 GBG84127.1 - 5.7 6.2 8.3 9.1 5.5 8.3 1.2 1 0 0 1 1 1 0 NOA36 protein DDE_Tnp_4 PF13359.6 GBG84128.1 - 1.2e-17 64.0 0.0 1.9e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84128.1 - 0.00059 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84128.1 - 0.03 14.0 0.1 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain DUF4366 PF14283.6 GBG84129.1 - 0.015 15.4 0.3 0.015 15.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DDHD PF02862.17 GBG84129.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 DDHD domain SAPS PF04499.15 GBG84129.1 - 4.4 6.0 7.1 5.5 5.7 7.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1943 PF09172.11 GBG84129.1 - 7.8 5.6 5.6 13 4.9 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) WD40 PF00400.32 GBG84131.1 - 6.8e-20 71.0 23.6 2.5e-05 24.9 0.1 7.6 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG84131.1 - 5.4e-13 49.1 4.3 0.00052 20.2 0.3 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG84131.1 - 3.3e-07 30.4 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Peptidase_M20 PF01546.28 GBG84132.1 - 1.1e-26 93.9 0.0 4.6e-14 52.6 0.0 3.1 2 1 0 2 2 2 2 Peptidase family M20/M25/M40 DUF4614 PF15391.6 GBG84132.1 - 0.14 12.1 7.4 0.38 10.7 7.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) FMO-like PF00743.19 GBG84133.1 - 2.6e-42 145.0 0.0 9.8e-17 60.6 0.0 4.1 4 0 0 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GBG84133.1 - 1.9e-13 50.4 0.3 2.4e-09 36.9 0.1 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GBG84133.1 - 8e-08 31.8 0.0 0.0003 20.1 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GBG84133.1 - 1.4e-07 31.6 0.1 4e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GBG84133.1 - 7e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GBG84133.1 - 0.0002 20.9 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GBG84133.1 - 0.00027 21.0 0.2 0.0077 16.2 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 GBG84133.1 - 0.00039 19.2 0.9 0.00066 18.5 0.9 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 GBG84133.1 - 0.0051 16.1 0.2 0.087 12.0 0.1 2.6 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 GBG84133.1 - 0.0072 15.4 0.1 0.015 14.4 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GBG84133.1 - 0.012 14.8 1.8 0.019 14.2 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 GBG84133.1 - 0.054 12.8 0.2 0.093 12.0 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GBG84133.1 - 0.19 12.3 3.3 0.32 11.6 1.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAGAT PF03982.13 GBG84134.1 - 1.9e-06 27.0 0.0 2.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Abhydrolase_6 PF12697.7 GBG84135.1 - 5.7e-07 30.4 0.9 2.6e-06 28.2 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG84135.1 - 0.0011 18.3 0.0 0.0038 16.5 0.0 1.9 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG84135.1 - 0.0074 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GBG84135.1 - 0.014 15.3 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 GBG84135.1 - 0.033 13.8 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative esterase BAR_2 PF10455.9 GBG84135.1 - 0.047 12.8 1.3 0.14 11.3 0.2 1.9 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking BAAT_C PF08840.11 GBG84135.1 - 0.12 12.3 0.0 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal SPX PF03105.19 GBG84135.1 - 0.21 11.4 6.6 0.34 10.8 0.3 2.1 2 0 0 2 2 2 0 SPX domain Myb_DNA-bind_4 PF13837.6 GBG84136.1 - 8.1e-09 35.7 1.9 2.1e-08 34.4 1.9 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG84136.1 - 0.00028 20.9 0.2 0.00062 19.8 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG84136.1 - 0.002 18.3 0.2 0.0059 16.8 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG84136.1 - 0.0027 18.0 3.0 0.0044 17.3 0.9 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG84137.1 - 1e-27 96.8 0.1 4e-27 94.8 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84137.1 - 4.1e-10 39.6 0.0 6.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84137.1 - 0.0013 18.4 0.1 0.0052 16.5 0.0 2.0 2 0 0 2 2 2 1 Transposase DDE domain Peroxin-3 PF04882.12 GBG84138.1 - 5.7e-40 137.7 7.5 3.6e-22 79.0 0.0 3.2 2 1 1 3 3 3 3 Peroxin-3 DUF1319 PF07028.11 GBG84138.1 - 0.078 13.2 0.2 0.46 10.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) PIN_2 PF10130.9 GBG84138.1 - 0.12 12.7 0.7 1.3 9.3 0.2 2.2 2 0 0 2 2 2 0 PIN domain DUF2175 PF09943.9 GBG84138.1 - 0.44 10.9 1.8 6.9 7.0 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Retrotrans_gag PF03732.17 GBG84139.1 - 0.0062 16.8 2.8 0.019 15.2 0.1 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein Period_C PF12114.8 GBG84139.1 - 9.7 5.7 12.1 2.7 7.5 8.2 2.2 2 0 0 2 2 2 0 Period protein 2/3C-terminal region rve PF00665.26 GBG84140.1 - 5.1e-09 36.4 0.1 8.6e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG84140.1 - 6.4e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SLC12 PF03522.15 GBG84142.1 - 0.82 8.6 19.4 0.86 8.6 19.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 GBG84142.1 - 1.4 8.9 15.1 1.8 8.5 15.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A BUD22 PF09073.10 GBG84142.1 - 2 7.6 53.3 2.6 7.3 53.3 1.0 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG84142.1 - 8.3 5.7 64.2 12 5.2 64.2 1.2 1 0 0 1 1 1 0 SDA1 MogR_DNAbind PF12181.8 GBG84143.1 - 0.061 13.2 0.6 0.061 13.2 0.6 1.7 2 0 0 2 2 2 0 DNA binding domain of the motility gene repressor (MogR) HalX PF08663.10 GBG84143.1 - 1.6 9.1 13.5 0.1 12.9 5.5 2.8 2 2 1 3 3 3 0 HalX domain SOAR PF16533.5 GBG84143.1 - 5.9 6.9 15.2 1.9 8.5 3.5 2.6 2 1 0 2 2 2 0 STIM1 Orai1-activating region GLE1 PF07817.13 GBG84144.1 - 1.2e-64 218.0 0.0 1.2e-64 218.0 0.0 1.8 2 0 0 2 2 2 1 GLE1-like protein RT_RNaseH_2 PF17919.1 GBG84145.1 - 1.3e-33 115.0 0.2 5e-33 113.1 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84145.1 - 5.8e-32 111.0 0.1 1.1e-31 110.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84145.1 - 6.8e-30 103.4 0.2 1.7e-29 102.2 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84145.1 - 1.6e-18 66.5 0.2 4.4e-18 65.1 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84145.1 - 6e-16 58.7 0.0 3.1e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG84145.1 - 0.00084 19.5 0.1 0.02 15.1 0.1 3.2 3 0 0 3 3 3 1 H2C2 zinc finger Sld5 PF05916.11 GBG84146.1 - 1.2e-06 29.0 0.0 1.7e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein RapA_C PF12137.8 GBG84146.1 - 0.0078 15.3 0.0 0.0087 15.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal AAA_9 PF12781.7 GBG84147.1 - 1.1e-60 204.5 6.6 3.9e-50 170.0 0.0 3.7 4 0 0 4 4 4 2 ATP-binding dynein motor region Dynein_heavy PF03028.15 GBG84147.1 - 1.7e-35 121.7 1.0 4.2e-33 114.0 0.0 3.3 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 GBG84147.1 - 6.5e-31 107.4 0.0 1.2e-30 106.5 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 GBG84147.1 - 1.5e-25 90.1 1.8 3.4e-25 88.9 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 GBG84147.1 - 3.6e-25 88.7 1.9 5.7e-25 88.1 1.9 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 GBG84147.1 - 2.8e-05 23.6 0.0 0.00022 20.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Fez1 PF06818.15 GBG84147.1 - 0.14 12.6 12.7 1.6 9.2 0.0 2.6 2 0 0 2 2 2 0 Fez1 DUF745 PF05335.13 GBG84147.1 - 0.14 11.9 13.4 0.18 11.5 12.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Laminin_II PF06009.12 GBG84147.1 - 0.76 9.8 12.6 3.4 7.7 10.0 2.4 2 0 0 2 2 2 0 Laminin Domain II Spc7 PF08317.11 GBG84147.1 - 1 8.2 17.4 2.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DegS PF05384.11 GBG84147.1 - 1.2 8.6 14.5 0.44 10.0 11.2 1.8 2 0 0 2 2 2 0 Sensor protein DegS ERM PF00769.19 GBG84147.1 - 3.2 7.5 22.7 18 5.1 0.1 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Myb_DNA-bind_4 PF13837.6 GBG84148.1 - 4.4e-11 43.0 0.2 4.4e-11 43.0 0.2 2.4 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG84148.1 - 0.00039 20.7 10.4 0.0011 19.2 2.5 2.3 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 GBG84149.1 - 4.9e-06 26.8 0.4 8.7e-06 26.0 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG84150.1 - 4.1e-05 23.9 1.7 7.8e-05 23.0 1.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG84151.1 - 2.4e-19 69.2 0.0 4e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84151.1 - 1.2e-07 31.9 0.0 2.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84151.1 - 0.00026 20.6 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG84151.1 - 0.44 8.7 9.8 0.59 8.3 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family Cnd2 PF05786.14 GBG84151.1 - 1.6 7.3 18.1 2.3 6.8 18.1 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 SDA1 PF05285.12 GBG84151.1 - 2.8 7.3 13.1 4 6.8 13.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG84151.1 - 10 4.3 8.5 14 3.8 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-bind_4 PF13837.6 GBG84152.1 - 1.4e-08 35.0 1.2 3.8e-08 33.6 1.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG84152.1 - 0.23 11.8 2.4 0.19 12.1 0.2 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG84153.1 - 0.0017 18.0 0.0 0.0095 15.6 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease TFIIF_alpha PF05793.12 GBG84155.1 - 0.014 14.0 16.3 0.014 14.0 16.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MDM1 PF15501.6 GBG84155.1 - 0.14 11.3 21.6 0.15 11.2 21.6 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 NPAT_C PF15712.5 GBG84155.1 - 0.15 10.7 8.5 0.13 10.9 8.5 1.0 1 0 0 1 1 1 0 NPAT C terminus SpoIIP PF07454.11 GBG84155.1 - 1.2 8.6 18.1 1.2 8.5 18.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 GBG84155.1 - 1.3 7.2 24.0 1.4 7.1 24.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GBG84155.1 - 1.5 7.2 25.8 1.6 7.1 25.8 1.0 1 0 0 1 1 1 0 Mpp10 protein PTPRCAP PF15713.5 GBG84155.1 - 2 8.7 30.8 2.5 8.4 30.8 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 GBG84155.1 - 2.1 7.0 22.6 2.1 7.0 22.6 1.0 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 GBG84155.1 - 2.2 8.9 12.3 2.6 8.7 12.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SRP-alpha_N PF04086.13 GBG84155.1 - 3.8 7.4 18.9 4.4 7.1 18.9 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Nop14 PF04147.12 GBG84155.1 - 4.6 5.3 23.4 4.7 5.3 23.4 1.0 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 GBG84155.1 - 6.2 6.9 13.7 7.5 6.6 13.7 1.2 1 0 0 1 1 1 0 DDHD domain CCSAP PF15748.5 GBG84155.1 - 6.3 6.9 22.4 6.9 6.8 22.4 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF2151 PF10221.9 GBG84155.1 - 7.4 5.0 11.0 7.2 5.1 11.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Peptidase_S64 PF08192.11 GBG84155.1 - 8.2 4.8 14.8 8.5 4.7 14.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2457 PF10446.9 GBG84155.1 - 9.1 5.3 22.0 11 5.0 22.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RVT_1 PF00078.27 GBG84156.1 - 7e-08 32.2 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84156.1 - 2.9e-05 24.6 0.0 7.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG84156.1 - 0.00018 21.3 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG84156.1 - 0.0022 18.5 0.0 0.0084 16.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG84156.1 - 0.02 14.7 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) APOBEC_C PF05240.14 GBG84156.1 - 0.15 12.0 0.2 0.53 10.3 0.2 2.0 1 0 0 1 1 1 0 APOBEC-like C-terminal domain LMBR1 PF04791.16 GBG84156.1 - 0.83 8.5 7.3 1.2 7.9 7.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5069 PF16798.5 GBG84156.1 - 1.2 9.3 7.3 0.16 12.1 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) PEP-utilisers_N PF05524.13 GBG84156.1 - 2.4 8.4 15.4 0.25 11.5 5.4 2.8 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DNA_pack_N PF02500.15 GBG84156.1 - 6.4 6.5 6.3 2.2 8.0 0.0 2.5 3 0 0 3 3 3 0 Probable DNA packing protein, N-terminus AAA_6 PF12774.7 GBG84158.1 - 1.6e-54 185.1 0.0 2.9e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DUF659 PF04937.15 GBG84158.1 - 2e-19 69.9 0.2 4.5e-19 68.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DDE_Tnp_4 PF13359.6 GBG84158.1 - 0.0031 17.2 0.0 0.0086 15.8 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_5 PF07728.14 GBG84158.1 - 0.011 15.7 0.0 0.98 9.4 0.0 2.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GBG84158.1 - 0.04 14.4 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T4_deiodinase PF00837.17 GBG84158.1 - 0.05 12.9 0.2 0.11 11.8 0.2 1.5 1 0 0 1 1 1 0 Iodothyronine deiodinase Defensin_beta_2 PF13841.6 GBG84158.1 - 0.44 11.1 2.9 1.2 9.7 2.9 1.7 1 0 0 1 1 1 0 Beta defensin AT_hook PF02178.19 GBG84158.1 - 0.46 10.5 5.6 1.2 9.3 5.6 1.7 1 0 0 1 1 1 0 AT hook motif Chromo PF00385.24 GBG84159.1 - 8.9e-11 41.5 0.0 1.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG84159.1 - 8.8e-09 35.3 2.4 2.3e-08 34.0 0.0 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG84159.1 - 8.2e-08 32.5 0.0 2.2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG84159.1 - 0.036 14.3 0.0 0.082 13.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG84160.1 - 6.1e-11 42.6 1.0 9.7e-11 41.9 0.1 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG84160.1 - 0.021 15.0 0.0 0.067 13.4 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG84160.1 - 0.048 14.0 0.1 0.048 14.0 0.1 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 GBG84160.1 - 0.13 13.2 0.1 0.31 12.0 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain NOA36 PF06524.12 GBG84161.1 - 2.8 7.2 4.9 3.4 6.9 4.9 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GBG84161.1 - 5.7 7.4 9.3 9.4 6.7 9.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain adh_short PF00106.25 GBG84162.1 - 1.1e-40 139.3 0.1 1.8e-40 138.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG84162.1 - 4.9e-30 104.8 0.4 1.4e-29 103.3 0.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG84162.1 - 1.2e-06 28.6 0.4 2.6e-06 27.5 0.2 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GBG84162.1 - 0.0028 17.2 0.1 0.0061 16.0 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3325 PF11804.8 GBG84162.1 - 0.051 13.7 0.2 0.15 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) SDA1 PF05285.12 GBG84162.1 - 0.055 12.9 22.0 0.019 14.4 18.7 1.8 2 0 0 2 2 2 0 SDA1 3Beta_HSD PF01073.19 GBG84162.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 GBG84162.1 - 0.13 12.2 0.5 0.31 10.9 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GBG84162.1 - 0.19 11.1 0.3 0.34 10.3 0.3 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Apt1 PF10351.9 GBG84162.1 - 2.7 6.7 5.5 4.1 6.1 5.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Astro_capsid_p PF12226.8 GBG84162.1 - 8.8 5.4 18.1 14 4.7 18.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EMC3_TMCO1 PF01956.16 GBG84163.1 - 3.8e-09 36.5 0.5 5e-09 36.1 0.5 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Ribosomal_L2_C PF03947.18 GBG84164.1 - 2.5e-46 157.0 3.7 3.8e-46 156.4 3.7 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GBG84164.1 - 4.9e-16 58.5 0.1 6e-15 55.0 0.0 2.4 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain MINDY_DUB PF04424.13 GBG84165.1 - 2.2e-32 111.5 0.0 4.9e-32 110.4 0.0 1.6 2 0 0 2 2 2 1 MINDY deubiquitinase RVT_1 PF00078.27 GBG84166.1 - 1.5e-35 122.7 0.0 2.5e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG84166.1 - 1.2e-07 31.5 0.0 2.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84166.1 - 6.6e-05 23.5 0.0 0.00016 22.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84166.1 - 0.00048 20.6 0.0 0.0015 19.1 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG84166.1 - 0.0025 17.6 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG84166.1 - 0.016 15.0 0.0 1.3 8.8 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease Thioredoxin PF00085.20 GBG84168.1 - 0.0074 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin adh_short PF00106.25 GBG84169.1 - 6.7e-43 146.4 1.4 4.4e-41 140.5 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG84169.1 - 3.4e-31 108.6 0.2 1.4e-30 106.6 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 GBG84169.1 - 4.5e-26 91.3 0.2 1.8e-25 89.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GBG84169.1 - 5.2e-20 72.8 0.1 2.2e-19 70.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KR PF08659.10 GBG84169.1 - 4.9e-08 33.1 0.3 4.9e-08 33.1 0.3 2.3 3 0 0 3 3 3 1 KR domain ADH_N PF08240.12 GBG84169.1 - 3.2e-05 23.8 0.0 0.0011 18.9 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 GBG84169.1 - 0.0015 18.0 0.3 0.0035 16.8 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GBG84169.1 - 0.01 16.1 0.1 1 9.6 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Polysacc_synt_2 PF02719.15 GBG84169.1 - 0.056 12.6 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GBG84169.1 - 0.18 11.2 0.0 0.47 9.8 0.0 1.7 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pkinase PF00069.25 GBG84170.1 - 3.5e-39 134.8 0.0 1.3e-19 70.6 0.1 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84170.1 - 1.9e-24 86.4 0.1 3.8e-12 46.0 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase HEAT_2 PF13646.6 GBG84170.1 - 2.4e-05 24.6 0.9 0.0021 18.4 0.0 4.1 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.23 GBG84170.1 - 0.0008 19.4 0.3 1.5 9.0 0.0 4.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GBG84170.1 - 0.011 15.9 3.9 0.47 10.8 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat TFCD_C PF12612.8 GBG84170.1 - 0.027 14.3 0.0 6.3 6.6 0.0 3.1 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal DUF3361 PF11841.8 GBG84170.1 - 0.052 13.5 2.7 4.4 7.2 0.1 3.8 2 2 0 2 2 2 0 Domain of unknown function (DUF3361) XPC-binding PF09280.11 GBG84170.1 - 0.11 12.3 0.3 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 XPC-binding domain KAP PF05804.12 GBG84170.1 - 0.19 9.8 2.8 0.55 8.3 0.2 2.5 3 0 0 3 3 3 0 Kinesin-associated protein (KAP) Myb_DNA-bind_4 PF13837.6 GBG84171.1 - 2.3e-05 24.7 1.1 3.5e-05 24.1 0.7 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG84171.1 - 0.034 14.2 0.4 0.034 14.2 0.4 1.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG84171.1 - 0.17 12.1 2.3 0.58 10.4 2.3 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG84172.1 - 7.1e-32 109.4 0.0 1.8e-31 108.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84172.1 - 5.3e-31 107.9 0.0 9.9e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84172.1 - 1.3e-18 67.2 0.0 3.4e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG84172.1 - 2.7e-06 27.8 0.0 6.7e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84172.1 - 0.00038 21.0 0.0 0.001 19.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF1564 PF07600.11 GBG84172.1 - 0.004 16.9 1.7 0.0085 15.8 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG84172.1 - 0.0048 17.1 0.9 0.023 15.0 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF1758 PF05585.12 GBG84172.1 - 0.04 13.7 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG84172.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Med25_VWA PF11265.8 GBG84173.1 - 1e-15 58.1 0.0 1.9e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A DUF3332 PF11810.8 GBG84173.1 - 0.75 9.4 4.0 1.7 8.3 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Med25_VWA PF11265.8 GBG84174.1 - 1e-15 58.1 0.0 1.9e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A DUF3332 PF11810.8 GBG84174.1 - 0.75 9.4 4.0 1.7 8.3 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) RWP-RK PF02042.15 GBG84175.1 - 1.3e-25 89.1 0.2 5.1e-25 87.2 0.1 2.1 2 0 0 2 2 2 1 RWP-RK domain PB1 PF00564.24 GBG84175.1 - 4.2e-14 52.3 0.1 8.3e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 PB1 domain bHLH-MYC_N PF14215.6 GBG84175.1 - 0.017 15.4 0.0 10 6.4 0.0 2.8 3 0 0 3 3 3 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal RICH PF05062.12 GBG84176.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 RICH domain FAM110_C PF14160.6 GBG84176.1 - 7.7 7.6 7.8 7.2 7.7 0.1 2.9 3 0 0 3 3 3 0 Centrosome-associated C terminus RR_TM4-6 PF06459.12 GBG84178.1 - 0.43 10.3 2.9 0.43 10.4 2.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.9 GBG84178.1 - 0.5 9.9 8.9 0.62 9.6 8.9 1.1 1 0 0 1 1 1 0 DDRGK domain UBA2_C PF16195.5 GBG84178.1 - 5.1 7.9 10.6 0.3 11.8 4.3 1.9 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus MPC PF03650.13 GBG84179.1 - 8.7e-37 125.6 0.1 9.2e-37 125.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers RT_RNaseH PF17917.1 GBG84180.1 - 5.1e-23 81.4 0.0 1.5e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84180.1 - 2.5e-22 78.8 0.0 6e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84180.1 - 1.2e-08 34.7 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG84180.1 - 6.8e-08 32.5 0.1 1.5e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Topo_Zn_Ribbon PF08272.11 GBG84180.1 - 0.039 13.6 0.3 0.087 12.5 0.3 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG84180.1 - 0.082 13.0 1.9 0.17 12.1 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG84182.1 - 4.4e-25 88.5 0.3 7.5e-25 87.7 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84182.1 - 1.1e-12 47.8 0.0 2.8e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG84182.1 - 2.4e-07 30.6 0.1 9.9e-06 25.4 0.1 2.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84182.1 - 1.4e-06 28.8 0.0 3.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG84182.1 - 4.3e-05 23.7 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG84182.1 - 0.0026 18.3 0.0 0.0057 17.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG84182.1 - 0.006 16.8 2.8 0.019 15.2 0.5 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG84182.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease HisKA PF00512.25 GBG84183.1 - 4.4e-09 36.3 0.1 6.5e-08 32.5 0.0 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain CHASE PF03924.13 GBG84183.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 CHASE domain SPX PF03105.19 GBG84183.1 - 0.97 9.3 2.7 1.5 8.7 2.7 1.3 1 0 0 1 1 1 0 SPX domain QWRF PF04484.12 GBG84183.1 - 2.3 7.9 6.0 4.4 7.0 6.0 1.4 1 0 0 1 1 1 0 QWRF family Prot_ATP_OB_N PF17758.1 GBG84184.1 - 0.037 13.7 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Nuc_sug_transp PF04142.15 GBG84185.1 - 3.6e-53 180.8 10.5 5.8e-53 180.1 10.5 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter RT_RNaseH_2 PF17919.1 GBG84185.1 - 3.2e-27 94.5 0.0 7e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84185.1 - 2.1e-24 85.8 0.0 4e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase UAA PF08449.11 GBG84185.1 - 3.2e-11 43.0 16.8 4.7e-11 42.4 16.8 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GBG84185.1 - 7.7e-07 29.4 19.5 0.0024 18.0 0.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family Phage_holin_5_2 PF16079.5 GBG84185.1 - 9.7 6.6 13.7 0.11 12.9 1.9 3.4 3 1 1 4 4 4 0 Phage holin family Hol44, in holin superfamily V Nuc_sug_transp PF04142.15 GBG84186.1 - 1.7e-33 116.1 1.2 2.9e-33 115.4 1.2 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter RT_RNaseH_2 PF17919.1 GBG84186.1 - 3.3e-27 94.4 0.0 5.9e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84186.1 - 1.8e-24 86.1 0.0 3.4e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase UAA PF08449.11 GBG84186.1 - 3.9e-09 36.2 6.1 6.1e-09 35.5 6.1 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GBG84186.1 - 7e-06 26.3 7.2 0.0021 18.3 0.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GBG84186.1 - 0.018 14.4 0.4 0.026 13.9 0.4 1.2 1 0 0 1 1 1 0 Triose-phosphate Transporter family Phage_holin_5_2 PF16079.5 GBG84186.1 - 0.91 9.9 9.3 0.073 13.4 1.6 2.9 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V Nuc_sug_transp PF04142.15 GBG84187.1 - 9.2e-33 113.7 11.9 1.1e-32 113.5 11.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GBG84187.1 - 0.0032 17.7 10.7 0.0041 17.3 10.7 1.2 1 0 0 1 1 1 1 EamA-like transporter family UAA PF08449.11 GBG84187.1 - 0.013 14.8 9.4 0.015 14.5 9.4 1.1 1 0 0 1 1 1 0 UAA transporter family OST3_OST6 PF04756.13 GBG84187.1 - 0.42 9.9 9.4 4.1 6.7 3.7 2.1 1 1 1 2 2 2 0 OST3 / OST6 family, transporter family Ribosomal_S9 PF00380.19 GBG84188.1 - 1.7e-32 112.4 0.1 2e-32 112.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RVT_1 PF00078.27 GBG84189.1 - 4.2e-05 23.2 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG84189.1 - 0.17 12.1 0.7 0.33 11.1 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG84190.1 - 1.3e-15 57.2 0.1 2.8e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84190.1 - 5e-08 33.2 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG84190.1 - 0.0019 18.4 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Kinesin PF00225.23 GBG84191.1 - 1.9e-75 253.9 4.5 7.3e-43 146.8 2.8 3.2 2 1 1 3 3 3 3 Kinesin motor domain DUF3490 PF11995.8 GBG84191.1 - 1.2e-52 177.9 2.5 1.2e-52 177.9 2.5 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3490) Microtub_bd PF16796.5 GBG84191.1 - 2.8e-18 66.3 0.5 1.8e-13 50.6 0.0 2.7 2 0 0 2 2 2 2 Microtubule binding APG6_N PF17675.1 GBG84191.1 - 0.0065 17.0 3.4 0.0065 17.0 3.4 3.3 4 0 0 4 4 4 1 Apg6 coiled-coil region DUF2730 PF10805.8 GBG84191.1 - 1.4 9.1 5.1 2.6 8.2 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TraC PF07820.12 GBG84191.1 - 1.4 9.3 10.8 1.5 9.2 0.9 3.8 3 0 0 3 3 3 0 TraC-like protein AAA_13 PF13166.6 GBG84191.1 - 5.5 5.5 7.9 1.1 7.9 2.9 2.1 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.11 GBG84191.1 - 5.7 5.7 19.5 0.021 13.7 5.7 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF4763 PF15960.5 GBG84191.1 - 8.4 5.6 15.7 0.05 12.9 4.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) DDE_Tnp_4 PF13359.6 GBG84193.1 - 2.2e-22 79.4 0.0 3.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84193.1 - 5e-10 39.3 0.0 1.2e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84193.1 - 0.00021 21.0 0.5 0.39 10.3 0.2 2.6 3 0 0 3 3 3 2 Transposase DDE domain Usp PF00582.26 GBG84194.1 - 1.6e-35 122.6 0.7 2e-35 122.3 0.7 1.0 1 0 0 1 1 1 1 Universal stress protein family RVT_1 PF00078.27 GBG84195.1 - 5.9e-24 84.8 0.0 1.9e-23 83.2 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG84196.1 - 1.1e-27 97.0 0.0 1.7e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84197.1 - 8.7e-21 74.2 0.0 1.9e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84197.1 - 1.2e-20 73.4 0.0 3.3e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG84197.1 - 3.1e-07 30.9 0.0 7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG84197.1 - 5.3e-07 29.4 0.0 8.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84197.1 - 2.5e-05 24.8 0.0 7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG84197.1 - 7.8e-05 22.6 8.8 0.036 14.2 2.0 2.7 2 0 0 2 2 2 2 Zinc knuckle Asp_protease PF09668.10 GBG84197.1 - 0.0054 16.5 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG84197.1 - 0.058 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease CorA PF01544.18 GBG84199.1 - 0.67 9.2 2.0 0.6 9.4 0.3 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PAC1 PF16094.5 GBG84199.1 - 1.7 7.8 5.6 3 6.9 5.6 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Pox_A_type_inc PF04508.12 GBG84199.1 - 7.8 6.5 12.5 0.084 12.8 2.7 3.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat UTP25 PF06862.12 GBG84200.1 - 1.7e-148 495.3 0.9 3e-147 491.2 0.9 2.1 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SpoU_methylase PF00588.19 GBG84201.1 - 2.3e-27 95.9 0.0 3.3e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family YL1 PF05764.13 GBG84201.1 - 0.51 10.4 7.1 0.85 9.7 7.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein WD40 PF00400.32 GBG84203.1 - 1.5e-21 76.3 12.4 1.6e-06 28.7 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat zf-RING_2 PF13639.6 GBG84203.1 - 3.7e-09 36.8 9.1 7.5e-09 35.8 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GBG84203.1 - 1.3e-08 34.6 9.8 2.4e-08 33.8 9.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ANAPC4_WD40 PF12894.7 GBG84203.1 - 1.5e-08 34.8 0.7 0.0075 16.5 0.1 3.7 3 1 1 4 4 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_3 PF13920.6 GBG84203.1 - 2.1e-08 33.9 7.8 3.4e-08 33.2 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG84203.1 - 5.6e-07 29.3 6.4 1.1e-06 28.4 6.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GBG84203.1 - 1.2e-06 28.2 7.8 2.1e-06 27.4 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG84203.1 - 1.5e-06 27.9 9.0 2.6e-06 27.2 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ge1_WD40 PF16529.5 GBG84203.1 - 5e-06 25.7 1.1 0.053 12.5 0.1 3.3 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-RING_UBOX PF13445.6 GBG84203.1 - 7.3e-06 25.9 2.3 8e-06 25.8 0.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GBG84203.1 - 0.00053 20.2 8.2 0.0013 19.0 8.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Nup160 PF11715.8 GBG84203.1 - 0.0023 16.6 0.0 0.005 15.5 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Zn_ribbon_17 PF17120.5 GBG84203.1 - 0.017 14.7 8.0 0.036 13.7 8.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 GBG84203.1 - 0.022 14.4 3.4 0.042 13.5 3.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_11 PF17123.5 GBG84203.1 - 0.034 13.9 4.1 0.094 12.5 4.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger ZapB PF06005.12 GBG84203.1 - 0.073 13.5 0.3 0.073 13.5 0.3 3.9 4 1 0 4 4 2 0 Cell division protein ZapB zf-RING_6 PF14835.6 GBG84203.1 - 0.11 12.4 2.9 0.21 11.5 2.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 GBG84203.1 - 0.36 10.7 8.0 0.8 9.6 8.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 GBG84203.1 - 0.62 10.2 7.1 1.1 9.3 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Baculo_IE-1 PF05290.11 GBG84203.1 - 0.93 9.4 4.9 2.1 8.3 4.9 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 GBG84203.1 - 2.1 8.6 8.4 4.6 7.5 8.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING NOA36 PF06524.12 GBG84203.1 - 6.4 6.0 14.5 23 4.2 14.5 1.9 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 GBG84204.1 - 2.5e-65 220.5 0.0 2.9e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84204.1 - 5.1e-34 117.7 0.0 6.4e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG84204.1 - 0.002 18.1 0.0 0.038 13.9 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 GBG84204.1 - 0.0066 16.1 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GBG84204.1 - 0.0078 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 GBG84204.1 - 0.033 13.8 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 GBG84204.1 - 0.095 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 GBG84204.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 GBG84204.1 - 0.16 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RVT_1 PF00078.27 GBG84205.1 - 5.3e-12 45.7 0.6 7.5e-12 45.2 0.6 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5625 PF18539.1 GBG84205.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5625) EVE PF01878.18 GBG84206.1 - 1e-41 142.3 0.1 1.3e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 EVE domain Pkinase_Tyr PF07714.17 GBG84207.1 - 2.7e-30 105.5 0.0 3.9e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG84207.1 - 1.2e-29 103.6 0.0 1.4e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-C3HC4_3 PF13920.6 GBG84207.1 - 8.1e-10 38.4 8.4 1.3e-09 37.8 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG84207.1 - 4.8e-06 26.3 9.3 8.4e-06 25.6 9.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 APH PF01636.23 GBG84207.1 - 0.025 14.5 0.2 0.044 13.7 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_5 PF14634.6 GBG84207.1 - 0.025 14.5 8.2 0.049 13.6 8.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 GBG84207.1 - 0.056 13.8 9.1 0.11 12.9 9.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 GBG84207.1 - 0.39 10.6 9.0 0.73 9.7 9.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 GBG84207.1 - 0.93 9.6 6.8 6.5 6.9 6.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon Cnd1_N PF12922.7 GBG84209.1 - 1 9.2 2.9 0.86 9.4 0.5 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term SAD_SRA PF02182.17 GBG84211.1 - 2.3e-49 167.1 0.1 5.9e-49 165.8 0.1 1.7 1 0 0 1 1 1 1 SAD/SRA domain PHD PF00628.29 GBG84211.1 - 1e-09 38.1 6.0 1e-09 38.1 6.0 4.0 4 1 0 4 4 1 1 PHD-finger zf-C3HC4_3 PF13920.6 GBG84211.1 - 2.6e-08 33.6 39.4 5.2e-06 26.2 9.0 4.9 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG84211.1 - 5e-08 32.8 23.0 1.3e-06 28.3 2.3 3.4 4 0 0 4 4 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG84211.1 - 2.6e-07 30.4 41.4 2.8e-05 23.9 11.7 4.1 3 1 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG84211.1 - 2.4e-06 27.3 24.0 0.00017 21.4 4.5 4.1 4 1 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG84211.1 - 2.4e-06 27.7 43.5 0.0011 19.2 13.3 3.9 3 1 0 3 3 3 3 Ring finger domain zf-C3HC4_4 PF15227.6 GBG84211.1 - 5e-06 26.6 21.5 0.00012 22.2 9.3 4.1 5 0 0 5 5 4 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 GBG84211.1 - 1.7e-05 24.7 26.1 3.4e-05 23.7 6.1 4.0 3 1 1 4 4 3 2 zinc-RING finger domain zf-RING_10 PF16685.5 GBG84211.1 - 0.0075 16.4 17.3 0.19 11.9 4.6 3.6 3 0 0 3 3 3 2 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 GBG84211.1 - 0.029 14.2 35.9 0.037 13.9 5.3 4.4 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 SDA1 PF05285.12 GBG84211.1 - 0.88 8.9 23.5 0.44 9.9 12.9 2.5 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 GBG84211.1 - 2.7 7.2 24.4 1.2 8.4 14.4 2.4 2 0 0 2 2 2 0 BUD22 zf-UDP PF14569.6 GBG84211.1 - 3.6 7.8 15.5 7 6.8 1.0 3.8 3 0 0 3 3 3 0 Zinc-binding RING-finger SpoIIIAH PF12685.7 GBG84211.1 - 5.5 6.8 20.1 2.2 8.1 0.1 3.2 3 0 0 3 3 3 0 SpoIIIAH-like protein Afi1 PF07792.12 GBG84211.1 - 5.9 7.4 14.3 0.56 10.7 5.7 2.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop53 PF07767.11 GBG84212.1 - 0.15 11.4 16.7 0.25 10.7 16.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GBG84212.1 - 0.37 9.0 11.8 0.48 8.7 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Prothymosin PF03247.14 GBG84212.1 - 0.43 11.0 14.1 0.9 10.0 14.1 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family Presenilin PF01080.17 GBG84212.1 - 5.6 5.6 4.8 6.7 5.4 4.8 1.1 1 0 0 1 1 1 0 Presenilin DUF3138 PF11336.8 GBG84213.1 - 0.11 11.1 0.9 0.13 10.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PA26 PF04636.13 GBG84213.1 - 0.18 10.7 9.7 0.2 10.5 9.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3629 PF12302.8 GBG84213.1 - 0.25 10.8 5.8 0.33 10.3 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) HemX PF04375.14 GBG84213.1 - 1.8 7.7 13.9 8.9 5.5 11.5 2.0 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase TTKRSYEDQ PF10212.9 GBG84213.1 - 2.3 7.1 13.4 2.4 7.0 13.4 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein RVT_1 PF00078.27 GBG84214.1 - 1.2e-24 87.1 0.1 2.1e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG84214.1 - 6.7e-09 36.0 0.1 1.6e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4187 PF13821.6 GBG84214.1 - 0.00097 18.9 0.7 0.0038 17.0 0.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG84214.1 - 0.0021 18.3 1.4 0.0068 16.6 0.2 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Bestrophin PF01062.21 GBG84215.1 - 9.4e-18 64.6 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel CheR_N PF03705.15 GBG84215.1 - 0.24 11.1 2.3 1.7 8.5 0.1 2.7 3 0 0 3 3 3 0 CheR methyltransferase, all-alpha domain DEAD PF00270.29 GBG84216.1 - 9.7e-51 172.0 0.0 1.9e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG84216.1 - 1.3e-29 102.8 0.0 2e-28 99.0 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG84216.1 - 1.7e-07 31.4 0.0 2.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TPT PF03151.16 GBG84217.1 - 4.1e-06 26.4 15.2 0.00057 19.3 1.8 2.4 1 1 1 2 2 2 2 Triose-phosphate Transporter family Chordopox_A13L PF05961.11 GBG84217.1 - 0.054 13.7 0.2 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus A13L protein ATP19 PF11022.8 GBG84217.1 - 0.13 12.7 0.1 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 ATP synthase subunit K EamA PF00892.20 GBG84217.1 - 0.38 10.9 17.3 1.9 8.6 17.3 2.0 1 1 0 1 1 1 0 EamA-like transporter family SNF5 PF04855.12 GBG84218.1 - 4.7e-33 115.0 0.0 1.4e-16 61.1 0.0 2.0 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 RVT_1 PF00078.27 GBG84219.1 - 5.4e-31 107.8 0.1 9.6e-31 107.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG84219.1 - 2.3e-17 63.3 0.0 4.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG84219.1 - 0.00023 21.2 0.2 0.00064 19.8 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Sec63 PF02889.16 GBG84220.1 - 9.8e-149 493.5 0.0 2.7e-78 262.7 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GBG84220.1 - 3.8e-51 173.3 0.1 3.8e-26 91.9 0.4 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 GBG84220.1 - 3.3e-25 89.1 0.0 2.8e-12 47.0 0.1 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GBG84220.1 - 1.8e-08 34.7 0.2 1.5e-06 28.5 0.0 3.5 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GBG84220.1 - 1.1e-06 29.0 0.0 0.023 14.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 GBG84220.1 - 2.7e-05 24.3 0.0 8.3e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 GBG84220.1 - 2.9e-05 23.3 0.0 0.25 10.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 GBG84220.1 - 0.0016 18.8 0.2 0.21 11.9 0.3 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GBG84220.1 - 0.0023 17.4 0.0 0.67 9.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.17 GBG84220.1 - 0.013 15.2 0.1 0.51 10.0 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_7 PF12775.7 GBG84220.1 - 0.028 13.9 0.0 3.6 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 GBG84220.1 - 0.075 12.4 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.21 GBG84220.1 - 0.17 11.3 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 GBG84220.1 - 0.34 10.7 3.2 13 5.4 0.0 3.5 3 1 0 4 4 4 0 AAA domain Myc_N PF01056.18 GBG84220.1 - 3 7.7 7.9 0.79 9.6 2.3 2.1 2 0 0 2 2 2 0 Myc amino-terminal region E_Pc_C PF06752.12 GBG84221.1 - 0.17 12.0 9.7 0.35 11.0 9.7 1.6 1 1 0 1 1 1 0 Enhancer of Polycomb C-terminus Methyltr_RsmB-F PF01189.17 GBG84222.1 - 2e-30 105.9 0.0 1.6e-16 60.5 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 GBG84222.1 - 0.00012 22.6 0.0 0.00026 21.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_25 PF13649.6 GBG84222.1 - 0.00014 22.5 0.0 0.00045 20.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GBG84222.1 - 0.00089 19.4 0.0 0.0046 17.1 0.0 2.1 3 0 0 3 3 3 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 GBG84222.1 - 0.0015 18.4 0.0 0.063 13.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG84222.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RT_RNaseH_2 PF17919.1 GBG84226.1 - 2.2e-29 101.4 0.0 1e-28 99.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84226.1 - 2.4e-24 85.6 0.0 1e-23 83.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84226.1 - 4.4e-17 62.4 0.0 1.3e-16 60.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain FAT PF02259.23 GBG84226.1 - 0.044 13.0 0.1 0.58 9.3 0.0 2.6 3 0 0 3 3 3 0 FAT domain Phage_GPO PF05929.11 GBG84226.1 - 0.19 11.3 2.2 0.29 10.7 0.0 2.3 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase ORMDL PF04061.14 GBG84227.1 - 7.3e-34 116.5 2.0 9.2e-34 116.2 2.0 1.1 1 0 0 1 1 1 1 ORMDL family ORMDL PF04061.14 GBG84228.1 - 2.5e-45 153.6 6.8 3e-45 153.3 6.8 1.1 1 0 0 1 1 1 1 ORMDL family Myb_DNA-bind_4 PF13837.6 GBG84230.1 - 4.5e-08 33.4 3.2 6.6e-08 32.8 3.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG84230.1 - 0.0042 17.1 0.8 0.0066 16.5 0.8 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG84230.1 - 0.028 14.7 1.2 0.049 13.9 1.2 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Tyrosinase PF00264.20 GBG84233.1 - 2.4e-28 100.0 7.9 1e-14 55.4 0.6 2.6 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG84233.1 - 5.5e-16 58.1 0.1 1.3e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 Polyphenol oxidase middle domain PPO1_KFDV PF12143.8 GBG84233.1 - 1.9e-07 31.3 0.0 3.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF_B2219) DUF2575 PF10837.8 GBG84234.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) NOA36 PF06524.12 GBG84234.1 - 2.9 7.1 7.1 4 6.7 7.1 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG84234.1 - 8 4.4 9.0 10 4.1 9.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4360 PF14273.6 GBG84235.1 - 4.7e-30 104.8 0.0 6.6e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PTPRCAP PF15713.5 GBG84235.1 - 0.011 16.1 14.6 0.018 15.4 14.6 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GBG84235.1 - 0.55 8.4 22.7 0.72 8.0 22.7 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG84235.1 - 0.6 8.5 19.9 0.83 8.0 19.9 1.1 1 0 0 1 1 1 0 Mpp10 protein RNA_pol_Rpc4 PF05132.14 GBG84235.1 - 2.3 8.6 6.9 4 7.9 6.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 GBG84235.1 - 3.3 7.0 25.2 4.7 6.5 25.2 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GBG84235.1 - 6.1 4.8 30.5 7.7 4.5 30.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 GBG84235.1 - 6.2 6.1 18.9 8.7 5.6 18.9 1.1 1 0 0 1 1 1 0 BUD22 ATG16 PF08614.11 GBG84236.1 - 0.0017 18.6 8.9 0.003 17.8 8.9 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 GBG84236.1 - 0.0035 17.4 1.1 0.0059 16.7 1.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 GBG84236.1 - 0.0036 17.2 7.4 0.0056 16.6 7.4 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Macoilin PF09726.9 GBG84236.1 - 0.0096 14.5 2.2 0.0099 14.5 2.2 1.0 1 0 0 1 1 1 1 Macoilin family DUF5082 PF16888.5 GBG84236.1 - 0.01 16.1 0.2 0.033 14.5 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) DUF2046 PF09755.9 GBG84236.1 - 0.013 14.8 3.6 0.043 13.0 3.5 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) IFT57 PF10498.9 GBG84236.1 - 0.029 13.3 0.4 0.039 12.9 0.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 GBG84236.1 - 0.032 13.7 4.6 0.043 13.3 4.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4618 PF15397.6 GBG84236.1 - 0.034 13.6 1.1 0.086 12.2 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Uso1_p115_C PF04871.13 GBG84236.1 - 0.039 14.3 2.4 0.074 13.4 2.4 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region V-SNARE PF05008.15 GBG84236.1 - 0.042 14.2 4.0 5.6 7.4 0.1 2.7 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Spc7 PF08317.11 GBG84236.1 - 0.062 12.2 1.8 0.083 11.8 1.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 GBG84236.1 - 0.08 13.0 2.3 0.12 12.5 2.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 GBG84236.1 - 0.081 13.0 6.4 0.47 10.5 6.2 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FAM184 PF15665.5 GBG84236.1 - 0.11 12.3 5.7 0.15 11.9 5.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Bacillus_HBL PF05791.11 GBG84236.1 - 0.13 12.1 1.2 0.22 11.3 1.2 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PikAIV_N PF18605.1 GBG84236.1 - 0.13 11.8 3.2 0.34 10.5 3.2 1.8 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain CdvA PF18822.1 GBG84236.1 - 0.17 11.7 1.0 0.27 11.1 1.0 1.3 1 0 0 1 1 1 0 CdvA-like coiled-coil domain YabA PF06156.13 GBG84236.1 - 0.18 12.5 1.7 0.63 10.7 1.5 1.8 1 1 0 1 1 1 0 Initiation control protein YabA DUF883 PF05957.13 GBG84236.1 - 0.2 12.3 4.1 0.8 10.4 2.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FUSC PF04632.12 GBG84236.1 - 0.26 9.8 5.1 0.36 9.3 5.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.22 GBG84236.1 - 0.26 11.5 1.8 0.59 10.4 1.8 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.11 GBG84236.1 - 0.27 11.3 3.1 0.64 10.1 3.1 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Lectin_N PF03954.14 GBG84236.1 - 0.28 10.9 4.4 4.4 7.1 0.4 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1640 PF07798.11 GBG84236.1 - 0.34 10.9 3.3 0.87 9.6 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4407 PF14362.6 GBG84236.1 - 0.34 10.2 5.7 0.3 10.4 4.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 GBG84236.1 - 0.95 9.9 4.2 2.5 8.6 1.7 2.3 1 1 1 2 2 2 0 Snapin/Pallidin TMF_DNA_bd PF12329.8 GBG84236.1 - 1.2 9.2 4.3 1.4 8.9 0.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 GBG84236.1 - 5.7 7.5 9.5 13 6.3 0.4 2.6 2 1 0 2 2 1 0 Cell division protein ZapB EF-hand_1 PF00036.32 GBG84237.1 - 1.9e-13 48.9 0.2 2.9e-05 23.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GBG84237.1 - 1.7e-12 47.6 0.2 6.2e-12 45.8 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG84237.1 - 5e-11 41.6 0.1 2.7e-06 26.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 GBG84237.1 - 1e-08 34.3 0.5 0.00021 20.6 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GBG84237.1 - 6.4e-07 29.1 0.3 0.00017 21.3 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 GBG84237.1 - 0.0097 16.2 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain DUF1456 PF07308.13 GBG84237.1 - 0.026 14.8 1.0 0.14 12.5 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1456) Tubulin_3 PF14881.6 GBG84238.1 - 1.6e-18 67.0 0.0 2.8e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 GBG84238.1 - 0.00038 20.7 0.0 0.00069 19.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Gcn1_N PF12074.8 GBG84239.1 - 0.22 10.8 2.3 0.38 10.0 2.3 1.3 1 0 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal RT_RNaseH_2 PF17919.1 GBG84240.1 - 4.1e-50 167.9 0.0 1.1e-29 102.4 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84240.1 - 3.2e-40 136.7 0.0 9.8e-30 103.0 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84240.1 - 8.4e-39 133.4 0.5 3.2e-32 111.9 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG84240.1 - 3.2e-15 56.0 0.1 7.9e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG84240.1 - 4.9e-08 32.8 0.0 3.9e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84240.1 - 1.1e-05 26.0 0.0 2.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF4392 PF14336.6 GBG84240.1 - 0.0001 21.9 0.0 0.15 11.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4392) gag-asp_proteas PF13975.6 GBG84240.1 - 0.0005 20.6 0.0 0.0017 18.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG84240.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Yop-YscD_ppl PF16693.5 GBG84240.1 - 0.063 12.7 0.8 20 4.5 0.0 3.9 6 0 0 6 6 6 0 Inner membrane component of T3SS, periplasmic domain Asp_protease PF09668.10 GBG84240.1 - 0.071 12.9 0.0 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease zf-H2C2 PF09337.10 GBG84240.1 - 0.1 12.8 0.0 0.39 11.0 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Es2 PF09751.9 GBG84240.1 - 4.6 6.9 14.6 7.9 6.1 14.6 1.3 1 0 0 1 1 1 0 Nuclear protein Es2 RVT_1 PF00078.27 GBG84241.1 - 2.4e-31 109.0 0.1 3.9e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG84241.1 - 4.6e-13 49.1 0.0 2.3e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain DPPIV_N PF00930.21 GBG84241.1 - 0.011 14.5 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nop14 PF04147.12 GBG84241.1 - 0.25 9.5 8.1 0.33 9.1 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG84241.1 - 6.1 5.0 9.8 8.6 4.5 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein GDP_Man_Dehyd PF16363.5 GBG84242.1 - 5.6e-48 164.0 0.0 7.2e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG84242.1 - 2.9e-44 151.3 0.0 3.8e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GBG84242.1 - 7.5e-11 41.7 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 GBG84242.1 - 2.6e-10 39.8 0.0 3.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GBG84242.1 - 3.3e-07 29.7 3.0 4.9e-07 29.2 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GBG84242.1 - 8e-06 25.2 0.0 2.5e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 GBG84242.1 - 0.00092 18.8 0.3 0.002 17.7 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family DUF4328 PF14219.6 GBG84242.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) adh_short PF00106.25 GBG84242.1 - 0.12 11.8 0.2 0.26 10.7 0.2 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Fzo_mitofusin PF04799.13 GBG84243.1 - 0.011 15.3 8.5 0.2 11.2 0.7 3.2 3 0 0 3 3 3 0 fzo-like conserved region Tup_N PF08581.10 GBG84243.1 - 0.031 14.6 1.1 0.031 14.6 1.1 3.3 3 0 0 3 3 3 0 Tup N-terminal F-112 PF09645.10 GBG84243.1 - 0.063 13.4 5.9 4.7 7.4 0.9 3.0 2 1 1 3 3 3 0 F-112 protein SHE3 PF17078.5 GBG84243.1 - 0.069 12.9 5.3 0.036 13.8 1.0 2.3 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 Golgin_A5 PF09787.9 GBG84243.1 - 0.11 11.9 16.6 0.024 14.1 4.5 2.7 2 1 1 3 3 3 0 Golgin subfamily A member 5 MobC PF05713.11 GBG84243.1 - 0.22 12.0 1.5 29 5.2 0.0 3.4 3 0 0 3 3 2 0 Bacterial mobilisation protein (MobC) DUF4404 PF14357.6 GBG84243.1 - 0.39 11.4 8.1 3.3 8.4 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Med11 PF10280.9 GBG84243.1 - 0.45 11.0 4.9 0.2 12.1 1.6 2.1 2 1 0 2 2 2 0 Mediator complex protein Spc7 PF08317.11 GBG84243.1 - 0.51 9.2 15.9 0.056 12.3 6.0 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 GBG84243.1 - 0.63 10.3 20.8 1.2 9.3 0.8 2.9 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 HalX PF08663.10 GBG84243.1 - 1.9 8.9 17.6 1.8 9.0 3.1 4.3 3 1 1 4 4 4 0 HalX domain Csm1_N PF18504.1 GBG84243.1 - 2.3 8.6 16.0 2.9 8.3 2.3 4.8 2 2 3 5 5 5 0 Csm1 N-terminal domain ZapB PF06005.12 GBG84243.1 - 2.4 8.7 16.5 0.39 11.2 2.8 3.7 2 1 2 4 4 4 0 Cell division protein ZapB FlxA PF14282.6 GBG84243.1 - 4 7.5 9.1 22 5.1 6.5 2.8 2 1 1 3 3 3 0 FlxA-like protein YabA PF06156.13 GBG84243.1 - 4.4 8.0 6.4 4.1 8.1 0.9 2.8 2 1 1 3 3 3 0 Initiation control protein YabA DUF1635 PF07795.11 GBG84243.1 - 6.1 6.6 10.2 2.8 7.8 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) TolA_bind_tri PF16331.5 GBG84243.1 - 7.4 6.7 11.9 28 4.9 0.1 4.2 3 2 1 4 4 4 0 TolA binding protein trimerisation DUF3450 PF11932.8 GBG84243.1 - 8.9 5.5 15.0 0.14 11.4 2.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF212 PF02681.14 GBG84244.1 - 9e-20 71.1 0.1 5.1e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 Divergent PAP2 family HMG_box PF00505.19 GBG84245.1 - 8.4e-22 77.4 0.7 9.2e-22 77.2 0.7 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GBG84245.1 - 3.3e-14 53.2 0.8 3.6e-14 53.1 0.8 1.0 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 GBG84245.1 - 8.7e-07 28.8 0.2 1.1e-06 28.5 0.2 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box 5 ABC_tran PF00005.27 GBG84246.1 - 1.3e-54 184.4 0.0 2.9e-29 102.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 GBG84246.1 - 1.5e-50 172.3 28.1 2.3e-30 105.9 5.7 3.3 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 GBG84246.1 - 2.9e-19 70.0 0.0 9.1e-08 32.3 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GBG84246.1 - 0.00097 18.8 1.5 0.016 14.9 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 GBG84246.1 - 0.0012 18.3 0.0 2.8 7.3 0.0 3.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 GBG84246.1 - 0.0043 17.2 0.0 1.7 9.0 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 GBG84246.1 - 0.0052 16.7 0.4 0.056 13.3 0.1 2.5 3 0 0 3 3 3 1 RsgA GTPase AAA_23 PF13476.6 GBG84246.1 - 0.0059 17.1 3.9 0.12 12.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 GBG84246.1 - 0.012 15.4 0.2 1.9 8.1 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain SRP54 PF00448.22 GBG84246.1 - 0.025 14.2 0.7 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GBG84246.1 - 0.16 12.3 0.0 5.4 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain MukB PF04310.12 GBG84246.1 - 0.17 11.6 1.1 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal MMR_HSR1 PF01926.23 GBG84246.1 - 0.18 11.9 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ery_res_leader1 PF08051.11 GBG84247.1 - 0.014 15.3 0.0 8.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Erythromycin resistance leader peptide DUF659 PF04937.15 GBG84248.1 - 1e-24 87.1 0.0 1.7e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG84248.1 - 1.7e-10 40.5 0.0 5.7e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CDC45 PF02724.14 GBG84249.1 - 0.26 9.5 16.7 0.33 9.2 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG84249.1 - 1.4 7.0 21.4 1.8 6.6 21.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG84249.1 - 4.1 5.4 22.6 5.2 5.0 22.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG84249.1 - 5.3 6.4 21.2 7.4 5.9 21.2 1.2 1 0 0 1 1 1 0 SDA1 SDA1 PF05285.12 GBG84250.1 - 0.03 13.8 48.9 0.036 13.5 48.9 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG84250.1 - 1.4 7.6 22.2 1.5 7.5 22.2 1.2 1 0 0 1 1 1 0 Presenilin FAM76 PF16046.5 GBG84250.1 - 9.1 5.5 11.3 11 5.3 11.3 1.3 1 0 0 1 1 1 0 FAM76 protein NPR3 PF03666.13 GBG84250.1 - 9.6 4.9 21.0 11 4.6 21.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 GBG84251.1 - 4.3 6.5 5.7 0.49 9.6 0.8 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Myb_DNA-bind_4 PF13837.6 GBG84252.1 - 0.00023 21.5 2.4 0.00035 20.9 2.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SDA1 PF05285.12 GBG84253.1 - 1.5 8.2 16.6 1.9 7.8 16.6 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG84253.1 - 6.5 4.8 18.1 8.6 4.4 18.1 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 GBG84254.1 - 0.28 11.3 29.0 0.41 10.7 29.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GBG84254.1 - 0.46 9.9 31.4 0.65 9.4 31.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG84254.1 - 0.96 8.7 27.3 1.7 7.9 27.3 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG84254.1 - 2.4 6.3 20.7 3.6 5.8 20.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GBG84254.1 - 8.7 5.0 9.3 12 4.5 9.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein WRC PF08879.10 GBG84255.1 - 1e-15 57.2 12.3 2.4e-11 43.1 2.8 3.0 2 0 0 2 2 2 2 WRC JmjC PF02373.22 GBG84257.1 - 0.032 14.6 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase eIF3_subunit PF08597.10 GBG84257.1 - 1.6 8.6 8.4 1.9e+02 1.8 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF659 PF04937.15 GBG84258.1 - 1.1e-20 74.0 0.0 2.4e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG84258.1 - 0.013 15.5 1.1 0.033 14.2 1.1 1.6 1 0 0 1 1 1 0 BED zinc finger Integrase_H2C2 PF17921.1 GBG84259.1 - 1.2e-13 50.9 0.3 1.2e-13 50.9 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Jnk-SapK_ap_N PF09744.9 GBG84259.1 - 0.0011 19.2 6.6 0.0011 19.2 6.6 1.9 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 Retrotrans_gag PF03732.17 GBG84259.1 - 0.042 14.1 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG84261.1 - 3.3e-25 88.9 0.1 5.7e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG84261.1 - 5.6e-18 64.8 0.4 2.3e-17 62.8 0.2 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG84261.1 - 2.4e-15 56.7 0.0 1e-14 54.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84261.1 - 7.8e-09 35.5 0.0 5.1e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84261.1 - 1.1e-08 35.3 0.0 4e-08 33.5 0.0 2.0 2 0 0 2 2 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG84261.1 - 1.2e-08 35.5 0.0 2.6e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84261.1 - 6.4e-08 33.1 0.0 1.4e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Dala_Dala_lig_N PF01820.21 GBG84261.1 - 1.3e-06 28.8 0.0 2.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus Asp_protease PF09668.10 GBG84261.1 - 3.5e-05 23.6 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG84261.1 - 0.00033 20.4 0.0 0.00085 19.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG84261.1 - 0.0065 16.7 1.3 0.21 11.8 0.0 2.9 2 0 0 2 2 2 1 H2C2 zinc finger Dala_Dala_lig_C PF07478.13 GBG84262.1 - 5.7e-07 29.3 0.0 0.51 9.8 0.1 3.1 2 1 1 3 3 3 3 D-ala D-ala ligase C-terminus Cwf_Cwc_15 PF04889.12 GBG84263.1 - 0.0017 18.1 12.8 0.0021 17.8 12.8 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.10 GBG84263.1 - 0.0039 17.5 2.1 0.0048 17.2 2.1 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 GBG84263.1 - 0.004 17.1 1.6 0.0043 17.0 1.6 1.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain DUF913 PF06025.12 GBG84263.1 - 0.025 13.6 0.3 0.028 13.4 0.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MCM_bind PF09739.9 GBG84263.1 - 0.051 12.0 0.2 0.061 11.8 0.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RNA_pol_Rpc4 PF05132.14 GBG84263.1 - 0.19 12.2 0.7 0.2 12.1 0.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF5520 PF17658.1 GBG84263.1 - 0.2 10.7 3.8 0.24 10.5 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) NPR3 PF03666.13 GBG84263.1 - 0.21 10.3 2.2 0.23 10.2 2.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 GBG84263.1 - 0.33 9.1 20.6 0.38 8.9 20.6 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 GBG84263.1 - 0.34 10.1 10.5 0.42 9.8 10.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIA PF03153.13 GBG84263.1 - 0.46 10.4 12.5 0.44 10.5 12.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 GBG84263.1 - 0.55 9.6 20.9 0.72 9.2 20.9 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG84263.1 - 0.58 8.9 0.6 0.57 8.9 0.6 1.0 1 0 0 1 1 1 0 Presenilin FmiP_Thoc5 PF09766.9 GBG84263.1 - 0.62 9.3 5.8 0.87 8.8 5.8 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF3402 PF11882.8 GBG84263.1 - 0.75 8.8 6.9 0.9 8.6 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) RNA_polI_A34 PF08208.11 GBG84263.1 - 1.2 9.1 8.7 1.5 8.8 8.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Utp14 PF04615.13 GBG84263.1 - 1.5 7.3 17.9 1.9 6.9 17.9 1.1 1 0 0 1 1 1 0 Utp14 protein XAP5 PF04921.14 GBG84263.1 - 2.1 8.1 8.8 2.6 7.8 8.8 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator GCIP PF13324.6 GBG84263.1 - 2.8 7.5 9.5 3.3 7.2 9.5 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4637 PF15470.6 GBG84263.1 - 7 6.4 15.3 11 5.7 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nucleo_P87 PF07267.11 GBG84263.1 - 8.5 5.1 11.3 9 5.0 11.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Trypan_PARP PF05887.11 GBG84263.1 - 8.8 6.3 14.7 11 6.0 14.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RT_RNaseH PF17917.1 GBG84265.1 - 3.2e-22 78.8 0.0 6.7e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84265.1 - 2.7e-20 72.3 0.0 6.4e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84265.1 - 1.3e-16 60.4 0.5 3.6e-16 59.0 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG84265.1 - 7e-06 26.6 0.0 0.00028 21.5 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84265.1 - 0.00022 21.7 0.2 0.0007 20.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG84265.1 - 0.0059 16.8 0.1 0.013 15.7 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG84265.1 - 0.0078 16.2 2.2 0.016 15.2 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG84265.1 - 0.014 15.2 0.0 0.054 13.3 0.1 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF4968 PF16338.5 GBG84265.1 - 0.05 13.9 0.0 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4968) Retrotrans_gag PF03732.17 GBG84265.1 - 0.057 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Pkinase PF00069.25 GBG84266.1 - 4.5e-45 154.1 0.0 6.2e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84266.1 - 2.5e-44 151.5 0.0 4e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG84266.1 - 0.037 13.9 1.2 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG84266.1 - 0.053 12.3 0.5 0.18 10.5 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase SDA1 PF05285.12 GBG84266.1 - 3.9 6.8 9.8 9.3 5.6 4.1 2.1 2 0 0 2 2 2 0 SDA1 DDRGK PF09756.9 GBG84268.1 - 0.014 15.0 14.1 0.026 14.1 14.1 1.5 1 0 0 1 1 1 0 DDRGK domain zf-CCHC PF00098.23 GBG84268.1 - 0.07 13.2 0.8 0.15 12.2 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1682 PF07946.14 GBG84268.1 - 0.17 11.1 13.6 0.23 10.6 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Perilipin PF03036.16 GBG84268.1 - 0.23 10.5 14.2 0.28 10.1 13.0 1.6 1 1 1 2 2 2 0 Perilipin family PIEZO PF15917.5 GBG84268.1 - 0.32 10.4 7.8 0.5 9.8 7.8 1.3 1 0 0 1 1 1 0 Piezo Presenilin PF01080.17 GBG84268.1 - 0.42 9.3 4.2 0.42 9.3 4.2 1.3 1 0 0 1 1 1 0 Presenilin MCU PF04678.13 GBG84268.1 - 0.46 10.6 3.2 0.69 10.0 3.2 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Casc1_N PF15927.5 GBG84268.1 - 3.2 7.4 22.5 5.3 6.7 22.5 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus zf-CCHC_2 PF13696.6 GBG84268.1 - 4.3 7.3 6.1 0.97 9.3 2.4 1.8 2 0 0 2 2 2 0 Zinc knuckle Connexin PF00029.19 GBG84268.1 - 4.8 6.9 5.7 7.5 6.2 5.7 1.3 1 0 0 1 1 1 0 Connexin DUF2058 PF09831.9 GBG84268.1 - 5.8 7.0 13.8 9.5 6.3 13.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Nucleo_P87 PF07267.11 GBG84268.1 - 7 5.4 8.8 10 4.9 8.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ALMT PF11744.8 GBG84268.1 - 9.8 4.9 7.5 12 4.5 7.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PPR_2 PF13041.6 GBG84269.1 - 2.3e-49 165.4 0.0 5e-09 36.2 0.0 10.3 5 2 7 12 12 12 10 PPR repeat family PPR_3 PF13812.6 GBG84269.1 - 3.6e-42 142.3 0.0 1.6e-10 40.9 0.0 8.4 7 2 2 9 9 9 7 Pentatricopeptide repeat domain PPR PF01535.20 GBG84269.1 - 3.9e-34 114.5 16.1 0.0001 22.3 0.2 11.6 12 0 0 12 12 12 7 PPR repeat PPR_long PF17177.4 GBG84269.1 - 4.4e-31 107.9 7.6 1.8e-10 40.5 0.0 7.1 3 2 5 8 8 8 6 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GBG84269.1 - 1e-29 101.9 0.0 4.8e-06 26.2 0.0 9.2 9 0 0 9 9 9 6 PPR repeat Exog_C PF18026.1 GBG84269.1 - 0.0013 18.8 0.0 4.3 7.5 0.0 4.0 3 0 0 3 3 3 1 Endo/exonuclease (EXOG) C-terminal domain GMP_synt_C PF00958.22 GBG84269.1 - 0.034 14.2 0.3 19 5.4 0.0 4.2 3 1 1 4 4 4 0 GMP synthase C terminal domain ODR4-like PF14778.6 GBG84270.1 - 5.3e-56 190.1 0.0 6.6e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 4-like PIG-H PF10181.9 GBG84271.1 - 4.4e-15 55.3 0.3 8.3e-15 54.4 0.3 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component SWIRM-assoc_2 PF16496.5 GBG84271.1 - 0.08 11.8 1.5 0.11 11.3 1.5 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal EbsA PF17255.2 GBG84271.1 - 0.21 11.9 2.3 0.24 11.8 1.1 1.6 2 0 0 2 2 2 0 EbsA-like protein BUD22 PF09073.10 GBG84272.1 - 2.6 7.3 81.8 0.02 14.3 72.0 1.8 1 1 1 2 2 2 0 BUD22 RVP_2 PF08284.11 GBG84273.1 - 4.1e-07 29.8 0.0 1e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84273.1 - 1.4e-06 28.9 0.0 2.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84273.1 - 1e-05 26.0 0.1 4e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG84273.1 - 0.00063 19.6 0.0 0.0017 18.1 0.0 1.7 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG84273.1 - 0.022 14.5 0.0 0.08 12.7 0.0 1.9 1 1 0 1 1 1 0 Aspartyl protease Rrn6 PF10214.9 GBG84273.1 - 0.48 8.9 5.6 0.59 8.6 5.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Arc_PepC_II PF06847.11 GBG84273.1 - 1.7 9.2 7.8 95 3.6 0.0 4.1 3 1 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II DUF659 PF04937.15 GBG84275.1 - 2.4e-28 98.9 0.0 4.9e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG84275.1 - 2.7e-06 27.1 0.1 5.1e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Spt20 PF12090.8 GBG84277.1 - 0.043 13.4 5.9 0.055 13.1 5.9 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 GBG84277.1 - 0.074 12.2 5.3 0.088 12.0 5.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FA_synthesis PF02504.15 GBG84278.1 - 0.083 11.9 0.0 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 Fatty acid synthesis protein DUF659 PF04937.15 GBG84279.1 - 6.9e-18 65.0 0.0 1.2e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG84279.1 - 0.00077 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG84280.1 - 5.9e-20 71.7 0.0 1.2e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84280.1 - 3.3e-19 68.8 0.0 1e-18 67.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84280.1 - 3.2e-10 40.2 0.0 1.2e-09 38.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG84280.1 - 0.0022 18.2 1.5 0.0054 17.0 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Dimer_Tnp_hAT PF05699.14 GBG84281.1 - 1.2e-10 41.0 0.1 2.4e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ARGLU PF15346.6 GBG84281.1 - 1.6 8.6 12.2 4.8 7.0 12.2 1.7 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 SDA1 PF05285.12 GBG84285.1 - 0.28 10.6 15.9 0.36 10.2 15.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG84285.1 - 1.6 6.9 16.8 2.5 6.2 16.8 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG84285.1 - 2.1 6.8 17.6 2.7 6.5 17.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YscO PF07321.12 GBG84286.1 - 0.028 14.4 8.1 0.81 9.6 4.5 2.5 1 1 1 2 2 2 0 Type III secretion protein YscO SHNi-TPR PF10516.9 GBG84286.1 - 0.098 12.1 0.1 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 SHNi-TPR zf-CCCH PF00642.24 GBG84287.1 - 0.014 15.3 2.4 0.043 13.8 2.4 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GBG84287.1 - 0.055 14.2 0.2 0.22 12.2 0.2 2.0 1 0 0 1 1 1 0 Torus domain zf-CCCH_4 PF18044.1 GBG84287.1 - 0.12 12.3 2.1 0.26 11.1 2.1 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger Snapin_Pallidin PF14712.6 GBG84288.1 - 0.024 15.1 0.9 0.046 14.2 0.1 1.8 1 1 1 2 2 2 0 Snapin/Pallidin EzrA PF06160.12 GBG84288.1 - 0.13 10.4 0.7 0.16 10.1 0.7 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Chlorophyllase2 PF12740.7 GBG84289.1 - 8.4e-13 47.8 0.0 1.4e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 GBG84289.1 - 2.2e-09 36.8 0.0 3.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.13 GBG84289.1 - 0.00067 18.3 0.0 0.016 13.8 0.0 2.1 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 GBG84289.1 - 0.00072 20.2 0.2 0.00099 19.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 GBG84290.1 - 5.6e-06 25.4 0.0 2.5e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 GBG84290.1 - 0.00012 21.2 0.0 0.00035 19.7 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase PAF-AH_p_II PF03403.13 GBG84290.1 - 0.00075 18.1 0.0 0.017 13.7 0.0 2.1 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 GBG84290.1 - 0.004 17.8 0.2 0.0052 17.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Myb_DNA-bind_4 PF13837.6 GBG84292.1 - 8.8e-05 22.8 2.3 8.8e-05 22.8 2.3 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG84292.1 - 0.00091 19.4 1.5 0.00091 19.4 1.5 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG84292.1 - 0.007 16.4 1.1 0.018 15.1 1.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG84292.1 - 0.01 16.0 0.4 0.027 14.7 0.4 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain RPN2_C PF18004.1 GBG84292.1 - 0.078 12.9 0.5 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain MADF_DNA_bdg PF10545.9 GBG84292.1 - 0.55 10.6 5.7 0.1 12.9 1.2 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG84294.1 - 3.1e-06 27.0 0.0 4.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84294.1 - 0.0046 16.6 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG84294.1 - 0.0069 16.7 0.1 0.015 15.7 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE domain F-box-like_2 PF13013.6 GBG84294.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain DDE_Tnp_1 PF01609.21 GBG84294.1 - 0.15 11.7 0.5 0.24 11.0 0.5 1.3 1 0 0 1 1 1 0 Transposase DDE domain DUF3967 PF13152.6 GBG84295.1 - 0.0019 17.9 0.7 0.47 10.3 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3967) Tim54 PF11711.8 GBG84295.1 - 0.0069 15.2 4.7 0.0099 14.7 4.7 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 UPF0184 PF03670.13 GBG84295.1 - 0.15 12.5 1.6 3.4 8.1 0.1 2.8 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) GAS PF13851.6 GBG84295.1 - 0.27 10.6 16.7 0.63 9.4 16.7 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 GBG84295.1 - 0.76 9.1 10.7 1.4 8.2 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPD52 PF04201.15 GBG84295.1 - 0.88 9.2 8.3 2.9 7.5 7.2 2.2 1 1 1 2 2 2 0 Tumour protein D52 family Baculo_PEP_C PF04513.12 GBG84295.1 - 0.97 9.5 3.6 0.62 10.1 0.3 2.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2115 PF09888.9 GBG84295.1 - 1.1 9.7 6.5 0.26 11.8 2.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) OMS28_porin PF03532.13 GBG84295.1 - 1.4 8.1 6.5 0.28 10.4 1.6 2.0 1 1 1 2 2 2 0 OMS28 porin CCDC-167 PF15188.6 GBG84295.1 - 5.9 7.3 11.1 20 5.6 5.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 UPF0242 PF06785.11 GBG84295.1 - 8.9 6.4 16.8 16 5.5 16.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exo84_C PF16528.5 GBG84296.1 - 1.4e-19 70.7 0.0 5.8e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 GBG84296.1 - 8.8e-13 48.2 0.2 2.2e-12 46.8 0.2 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 GBG84296.1 - 1.6e-05 25.0 0.8 5.7e-05 23.2 0.1 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 RVT_1 PF00078.27 GBG84297.1 - 8.6e-59 198.7 0.6 3e-28 98.9 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84297.1 - 4.2e-25 87.7 0.0 1.3e-24 86.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84297.1 - 3.6e-23 81.8 0.0 7.8e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Beta_helix PF13229.6 GBG84297.1 - 8.5e-11 42.0 3.0 1.9e-05 24.5 0.3 2.8 3 0 0 3 3 3 2 Right handed beta helix region Asp_protease_2 PF13650.6 GBG84297.1 - 1.5e-07 31.9 0.0 1.1e-06 29.2 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84297.1 - 9.4e-07 29.3 0.0 1.6e-05 25.4 0.0 3.0 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84297.1 - 3.1e-06 27.0 0.0 1e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84297.1 - 2.4e-05 24.1 0.0 0.0041 16.9 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Sporozoite_P67 PF05642.11 GBG84297.1 - 0.00026 19.2 21.4 0.00026 19.2 21.4 2.2 2 0 0 2 2 2 1 Sporozoite P67 surface antigen EPL1 PF10513.9 GBG84298.1 - 2.7e-13 50.6 3.5 2.7e-13 50.6 3.5 3.4 4 1 0 4 4 4 1 Enhancer of polycomb-like SR-25 PF10500.9 GBG84298.1 - 2 8.0 5.8 0.22 11.1 0.9 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 GBG84299.1 - 2.2e-29 102.5 1.5 2.5e-29 102.4 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84299.1 - 4.2e-27 94.1 0.0 2.3e-26 91.7 0.0 2.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84299.1 - 4.4e-24 84.8 1.2 5.2e-23 81.3 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG84299.1 - 1.5e-06 28.7 0.0 4.3e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84299.1 - 3.5e-06 27.6 0.0 8.8e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG84299.1 - 3.6e-05 23.5 0.0 6.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG84299.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG84299.1 - 0.0017 18.6 1.2 0.01 16.1 0.7 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein CsgE PF10627.9 GBG84299.1 - 6.1 7.1 6.0 16 5.8 6.0 1.7 1 0 0 1 1 1 0 Curli assembly protein CsgE TMF_TATA_bd PF12325.8 GBG84299.1 - 7.7 6.8 18.6 2.2 8.5 4.4 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CompInhib_SCIN PF11546.8 GBG84300.1 - 0.054 13.5 5.4 0.28 11.2 5.4 2.3 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN PRIMA1 PF16101.5 GBG84300.1 - 1.3 9.0 3.4 4 7.5 3.4 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mersacidin PF16934.5 GBG84301.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) DUF659 PF04937.15 GBG84302.1 - 1.5e-15 57.3 0.1 6.5e-15 55.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) UQ_con PF00179.26 GBG84303.1 - 4.7e-41 139.7 0.1 5.7e-41 139.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GBG84303.1 - 0.035 14.4 0.2 0.06 13.6 0.2 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 GBG84303.1 - 0.053 13.4 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 UEV domain DUF659 PF04937.15 GBG84304.1 - 6.3e-12 45.6 0.0 1.4e-11 44.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) PH PF00169.29 GBG84305.1 - 2.6e-15 56.8 0.1 1.2e-07 32.1 0.1 2.8 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 GBG84305.1 - 0.13 12.7 3.2 25 5.4 2.6 3.4 2 1 0 2 2 2 0 Pleckstrin homology domain RVT_1 PF00078.27 GBG84306.1 - 3.1e-27 95.5 0.1 4.5e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84306.1 - 0.013 16.1 0.0 0.047 14.3 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease SSP160 PF06933.11 GBG84307.1 - 0.25 9.5 13.3 0.32 9.1 13.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PhoLip_ATPase_C PF16212.5 GBG84308.1 - 8e-60 202.7 22.5 9.6e-60 202.4 22.5 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal DUF4169 PF13770.6 GBG84308.1 - 0.084 13.2 0.7 0.12 12.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) RVT_1 PF00078.27 GBG84309.1 - 5.2e-08 32.7 0.0 8.5e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG84310.1 - 2.8e-29 102.2 0.1 6.8e-29 101.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84310.1 - 1.7e-23 82.9 0.1 6.8e-23 81.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84310.1 - 6e-23 80.8 0.0 1.8e-22 79.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84310.1 - 7.3e-18 64.4 0.1 1.8e-17 63.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Integrin_b_cyt PF08725.11 GBG84310.1 - 0.084 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain TolA_bind_tri PF16331.5 GBG84310.1 - 0.086 12.9 3.5 0.2 11.7 3.5 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation HrpB7 PF09486.10 GBG84310.1 - 0.39 11.1 4.6 0.37 11.2 2.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) RVT_1 PF00078.27 GBG84311.1 - 1.3e-30 106.6 0.0 2.1e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG84311.1 - 4.1e-16 58.8 0.0 8.2e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84311.1 - 3.4e-11 43.4 0.0 7.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Peptidase_C39 PF03412.15 GBG84311.1 - 0.11 12.3 0.1 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Peptidase C39 family PhoLip_ATPase_N PF16209.5 GBG84313.1 - 3.5e-24 84.3 2.6 6.5e-24 83.4 2.6 1.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GBG84313.1 - 8e-12 45.1 1.2 1.3e-10 41.3 0.0 3.0 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GBG84313.1 - 1.3e-06 28.9 0.9 0.00099 19.5 0.1 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GBG84313.1 - 1.5e-05 24.6 0.1 0.15 11.6 0.0 2.4 2 0 0 2 2 2 2 E1-E2 ATPase BRD4_CDT PF17105.5 GBG84313.1 - 0.23 11.1 2.5 0.75 9.4 1.8 2.1 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 RT_RNaseH PF17917.1 GBG84314.1 - 3.5e-20 72.3 0.9 5e-20 71.8 0.2 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84314.1 - 8.8e-12 44.9 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG84314.1 - 0.036 13.7 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2722 PF10846.8 GBG84315.1 - 9.8 5.0 14.7 13 4.5 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) WD40 PF00400.32 GBG84316.1 - 1.4e-66 218.8 32.4 2.7e-11 43.8 0.7 9.6 9 1 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG84316.1 - 5e-22 78.0 2.2 6e-05 23.3 0.0 5.9 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 GBG84316.1 - 3.6e-10 40.2 0.0 7.5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 GBG84316.1 - 3.5e-09 36.8 0.0 0.014 15.3 0.0 4.0 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GBG84316.1 - 3.4e-08 32.8 0.2 0.047 12.6 0.0 4.6 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 GBG84316.1 - 7.5e-05 22.2 3.9 4.8 6.4 0.0 4.6 2 2 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 GBG84316.1 - 0.00059 18.3 0.0 0.21 9.9 0.0 2.6 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 GBG84316.1 - 0.00074 18.3 3.9 1.3 7.5 0.0 3.9 3 1 0 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 GBG84316.1 - 0.00095 19.0 6.7 1.5 8.8 0.4 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 GBG84316.1 - 0.004 17.1 0.5 2.7 7.9 0.0 3.7 3 1 0 3 3 3 1 Transcription factor IIIC subunit delta N-term Cytochrom_D1 PF02239.16 GBG84316.1 - 0.023 13.3 0.0 0.064 11.8 0.0 1.8 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40_like PF17005.5 GBG84316.1 - 0.033 13.5 0.0 21 4.3 0.0 3.5 4 0 0 4 4 4 0 WD40-like domain IKI3 PF04762.12 GBG84316.1 - 0.06 11.3 0.0 2.5 6.0 0.0 2.3 2 0 0 2 2 2 0 IKI3 family Dscam_C PF12355.8 GBG84317.1 - 0.004 18.1 2.9 0.004 18.1 2.9 2.2 2 0 0 2 2 2 1 Down syndrome cell adhesion molecule C terminal F-box-like PF12937.7 GBG84317.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 GBG84317.1 - 0.038 13.9 0.5 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 F-box domain BRICHOS PF04089.14 GBG84317.1 - 0.085 13.1 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 BRICHOS domain CAP_N PF01213.19 GBG84317.1 - 0.94 8.9 3.6 1.5 8.2 3.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMEM171 PF15471.6 GBG84317.1 - 4.4 6.2 5.6 8.5 5.3 4.6 1.8 2 0 0 2 2 2 0 Transmembrane protein family 171 TPR_2 PF07719.17 GBG84318.1 - 1.6e-20 71.5 13.4 0.00023 21.1 0.0 7.0 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 GBG84318.1 - 9.2e-18 62.9 7.5 0.0056 16.8 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG84318.1 - 9.3e-18 63.2 11.7 0.0014 18.4 0.0 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 GBG84318.1 - 9.4e-11 41.2 2.4 0.0026 17.4 0.0 6.0 4 2 2 6 6 6 4 TPR repeat RVP_2 PF08284.11 GBG84318.1 - 6.9e-09 35.6 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease TPR_12 PF13424.6 GBG84318.1 - 2.5e-08 34.1 21.0 3e-07 30.6 0.2 5.6 5 2 1 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG84318.1 - 1.2e-07 32.2 0.0 0.00015 22.3 0.1 6.0 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 GBG84318.1 - 8.5e-07 29.4 19.0 0.0011 19.4 1.2 5.0 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GBG84318.1 - 1e-06 29.0 28.8 0.016 16.0 0.1 8.2 5 3 4 9 9 7 2 Tetratricopeptide repeat Retrotrans_gag PF03732.17 GBG84318.1 - 5.8e-05 23.3 0.5 0.00044 20.5 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG84318.1 - 0.00019 22.0 0.0 0.00047 20.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease ANAPC3 PF12895.7 GBG84318.1 - 0.0002 21.5 8.4 0.17 12.2 0.0 3.9 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 GBG84318.1 - 0.00024 21.0 3.0 0.68 10.0 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG84318.1 - 0.00092 19.4 5.5 1.8 9.1 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG84318.1 - 0.0064 16.4 9.3 11 6.3 0.0 6.2 7 1 1 8 8 7 0 Tetratricopeptide repeat gag-asp_proteas PF13975.6 GBG84318.1 - 0.0084 16.6 0.0 0.026 15.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TPR_10 PF13374.6 GBG84318.1 - 0.033 14.1 11.5 1.2 9.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-CCHC PF00098.23 GBG84319.1 - 0.01 15.9 3.1 0.026 14.6 3.1 1.7 1 0 0 1 1 1 0 Zinc knuckle SAP PF02037.27 GBG84319.1 - 0.011 15.5 0.1 0.032 14.0 0.1 1.8 1 0 0 1 1 1 0 SAP domain Rho_N PF07498.12 GBG84319.1 - 0.012 15.5 0.2 0.012 15.5 0.2 2.0 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain zf-CCHC_5 PF14787.6 GBG84319.1 - 0.023 14.4 2.1 0.057 13.1 2.1 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RT_RNaseH PF17917.1 GBG84320.1 - 9.7e-21 74.0 0.0 1.7e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84320.1 - 1.4e-11 44.3 0.0 2.8e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG84320.1 - 0.18 10.0 29.4 0.25 9.5 29.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG84320.1 - 0.24 10.8 26.7 0.33 10.3 26.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG84320.1 - 0.28 9.4 18.7 0.42 8.8 18.7 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG84320.1 - 0.71 9.1 26.5 0.98 8.7 26.5 1.1 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 GBG84320.1 - 0.94 9.5 26.9 1.5 8.9 26.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein FAM60A PF15396.6 GBG84321.1 - 0.0067 16.5 3.3 0.0075 16.3 3.3 1.2 1 0 0 1 1 1 1 Protein Family FAM60A CSRNP_N PF16019.5 GBG84321.1 - 0.0075 16.2 3.4 0.0075 16.2 3.4 1.5 2 0 0 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus RNase_H2_suC PF08615.11 GBG84321.1 - 0.14 12.4 3.7 0.7 10.1 3.7 1.9 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Neur_chan_memb PF02932.16 GBG84321.1 - 2 8.4 5.0 2.5 8.1 5.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_3_Rpc31 PF11705.8 GBG84321.1 - 5.2 7.3 16.4 0.1 12.8 9.4 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Integrase_H2C2 PF17921.1 GBG84322.1 - 4.8e-17 61.8 0.8 1.3e-14 54.1 0.1 2.7 2 1 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG84322.1 - 5.7e-16 58.8 0.0 1.3e-15 57.6 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG84322.1 - 5.5e-14 52.3 0.8 1.1e-13 51.3 0.8 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84322.1 - 5.6e-05 23.1 0.1 0.00013 22.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG84322.1 - 0.0067 16.6 0.0 0.036 14.3 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 GBG84322.1 - 0.039 13.7 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Rhamno_transf PF11316.8 GBG84322.1 - 0.11 11.9 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase tRNA_lig_CPD PF08302.11 GBG84322.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain DUF3138 PF11336.8 GBG84323.1 - 0.13 10.8 2.3 0.2 10.3 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MDM10 PF12519.8 GBG84323.1 - 2.2 7.1 13.2 2.9 6.6 13.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Herpes_UL25 PF01499.16 GBG84323.1 - 3 6.2 7.7 5 5.5 7.7 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family REV PF00424.18 GBG84323.1 - 4 7.5 10.6 0.085 12.9 0.7 2.5 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) PBP1_TM PF14812.6 GBG84324.1 - 0.15 12.5 6.0 0.38 11.2 6.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RVT_1 PF00078.27 GBG84325.1 - 2.2e-25 89.5 0.0 3.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UvrD-helicase PF00580.21 GBG84326.1 - 0.11 12.1 10.2 0.14 11.6 10.2 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF678 PF05077.12 GBG84326.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF678) Dapper PF15268.6 GBG84326.1 - 1.7 7.4 26.5 2 7.1 26.5 1.1 1 0 0 1 1 1 0 Dapper Apolipo_F PF15148.6 GBG84326.1 - 6 6.3 9.0 0.56 9.7 2.9 2.0 1 1 1 2 2 2 0 Apolipoprotein F FGGY_N PF00370.21 GBG84329.1 - 1.9e-32 112.7 0.0 3e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GBG84329.1 - 6e-22 78.3 0.1 1.5e-21 77.1 0.1 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RT_RNaseH_2 PF17919.1 GBG84330.1 - 9e-34 115.5 0.1 1.6e-33 114.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84330.1 - 5.2e-27 94.2 0.1 9.5e-27 93.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84330.1 - 6.8e-14 51.7 0.7 3.1e-13 49.6 0.1 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain USP19_linker PF16602.5 GBG84331.1 - 0.064 13.8 0.2 0.16 12.5 0.2 1.6 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase RT_RNaseH_2 PF17919.1 GBG84332.1 - 1.9e-10 40.7 0.0 5.2e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84332.1 - 2e-10 40.6 0.1 3.3e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG84332.1 - 8.8e-08 32.0 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84332.1 - 1.1e-07 32.4 0.0 2.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84332.1 - 4.1e-07 30.5 0.0 1.5e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG84332.1 - 0.0043 17.3 0.1 0.018 15.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG84332.1 - 0.0079 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG84332.1 - 2.6 8.7 8.3 2 9.1 0.1 3.1 3 0 0 3 3 3 0 SlyX Retrotrans_gag PF03732.17 GBG84333.1 - 0.0012 19.1 0.1 0.0058 16.9 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Phage_lysozyme PF00959.19 GBG84333.1 - 0.089 13.3 0.1 0.54 10.7 0.0 2.4 2 0 0 2 2 2 0 Phage lysozyme Astro_capsid_p2 PF16580.5 GBG84333.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal tail of astrovirus capsid projection or spike BUD22 PF09073.10 GBG84334.1 - 0.02 14.3 19.2 0.022 14.2 19.2 1.0 1 0 0 1 1 1 0 BUD22 Slu7 PF11708.8 GBG84334.1 - 0.026 14.3 12.6 0.029 14.1 12.6 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DNA_pol_phi PF04931.13 GBG84334.1 - 0.059 11.5 19.6 0.07 11.2 19.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Spore_coat_CotO PF14153.6 GBG84334.1 - 0.085 12.8 19.2 0.1 12.6 19.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PA26 PF04636.13 GBG84334.1 - 0.16 10.9 9.9 0.16 10.9 9.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) NPR3 PF03666.13 GBG84334.1 - 0.22 10.2 12.4 0.26 10.0 12.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 GBG84334.1 - 0.28 11.2 7.4 0.28 11.2 7.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2151 PF10221.9 GBG84334.1 - 0.37 9.3 13.0 0.4 9.2 13.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator RPOL_N PF14700.6 GBG84334.1 - 0.37 10.1 11.9 0.4 10.0 11.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal PIEZO PF15917.5 GBG84334.1 - 0.41 10.1 12.1 0.52 9.7 12.1 1.3 1 0 0 1 1 1 0 Piezo Nha1_C PF08619.10 GBG84334.1 - 0.7 9.0 23.8 0.75 8.9 23.8 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Pox_Ag35 PF03286.14 GBG84334.1 - 0.72 9.6 19.2 0.86 9.4 19.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 GBG84334.1 - 0.76 10.0 31.3 1.2 9.4 31.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Presenilin PF01080.17 GBG84334.1 - 0.87 8.3 11.8 0.79 8.4 11.8 1.0 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 GBG84334.1 - 0.92 8.9 26.1 1.1 8.6 26.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SpoVR PF04293.13 GBG84334.1 - 0.97 8.0 8.7 1 8.0 8.7 1.1 1 0 0 1 1 1 0 SpoVR like protein RR_TM4-6 PF06459.12 GBG84334.1 - 1.1 9.1 19.3 1.1 9.0 19.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RPN2_C PF18004.1 GBG84334.1 - 1.1 9.2 22.3 1.5 8.8 22.3 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Vfa1 PF08432.10 GBG84334.1 - 1.3 9.4 21.3 1.5 9.1 21.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2797 PF10977.8 GBG84334.1 - 1.3 8.9 8.9 1.6 8.6 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Sec62 PF03839.16 GBG84334.1 - 1.3 8.5 15.1 1.5 8.3 15.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SpoIIP PF07454.11 GBG84334.1 - 1.5 8.2 12.3 1.9 7.9 12.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3584 PF12128.8 GBG84334.1 - 1.8 5.9 20.0 2.1 5.7 20.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DDHD PF02862.17 GBG84334.1 - 2.1 8.5 5.1 2.4 8.3 5.1 1.1 1 0 0 1 1 1 0 DDHD domain Endostatin PF06482.11 GBG84334.1 - 2.5 7.5 5.1 2.7 7.4 5.1 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Zip PF02535.22 GBG84334.1 - 2.7 7.1 8.0 3.1 6.9 8.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cellulose_synt PF03552.14 GBG84334.1 - 3.5 6.0 7.6 4 5.8 7.6 1.0 1 0 0 1 1 1 0 Cellulose synthase CDC27 PF09507.10 GBG84334.1 - 3.6 6.9 26.4 4.1 6.7 26.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPL5 PF18168.1 GBG84334.1 - 4.9 6.3 11.3 6.1 6.0 11.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 SLC12 PF03522.15 GBG84334.1 - 5 6.0 10.5 5.4 5.9 10.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RNA_pol_Rpc4 PF05132.14 GBG84334.1 - 5.7 7.4 11.6 7.8 6.9 11.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1168 PF06658.12 GBG84334.1 - 5.7 6.8 31.1 7.4 6.4 31.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Na_trans_assoc PF06512.13 GBG84334.1 - 6.2 7.0 20.0 7.1 6.9 20.0 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Membralin PF09746.9 GBG84334.1 - 6.5 5.7 5.6 6.4 5.7 5.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein Protocadherin PF08374.11 GBG84334.1 - 6.6 6.7 6.2 7.3 6.5 6.2 1.1 1 0 0 1 1 1 0 Protocadherin Neur_chan_memb PF02932.16 GBG84334.1 - 7.6 6.5 6.8 8.3 6.4 6.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 GBG84334.1 - 7.6 4.7 18.9 9.3 4.4 18.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CSRNP_N PF16019.5 GBG84334.1 - 7.6 6.4 11.7 9.1 6.1 11.7 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF1764 PF08576.10 GBG84334.1 - 8.1 7.4 22.5 13 6.8 22.5 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Tim54 PF11711.8 GBG84334.1 - 8.3 5.1 16.5 11 4.7 16.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Afi1 PF07792.12 GBG84334.1 - 9.1 6.8 14.2 13 6.3 14.2 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2201_N PF13203.6 GBG84334.1 - 9.3 5.8 10.6 10 5.6 10.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain AAA_23 PF13476.6 GBG84334.1 - 9.8 6.6 27.9 14 6.1 27.9 1.2 1 0 0 1 1 1 0 AAA domain RAP1 PF07218.11 GBG84335.1 - 0.13 10.5 3.9 0.25 9.6 3.9 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF755 PF05501.11 GBG84335.1 - 0.78 10.0 10.5 2.2 8.6 10.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MID_MedPIWI PF18296.1 GBG84337.1 - 4.3e-24 85.7 0.0 1.3e-21 77.5 0.0 2.7 1 1 0 1 1 1 1 MID domain of medPIWI RVT_1 PF00078.27 GBG84337.1 - 2.6e-23 82.7 0.2 5.3e-23 81.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med13_C PF06333.12 GBG84337.1 - 2.7e-06 26.9 6.8 0.00088 18.6 1.3 3.6 2 2 0 2 2 2 2 Mediator complex subunit 13 C-terminal domain gag-asp_proteas PF13975.6 GBG84337.1 - 1.3e-05 25.6 0.0 3.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84337.1 - 6.4e-05 23.5 0.0 0.00018 22.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG84337.1 - 0.00021 21.0 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84337.1 - 0.00055 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG84337.1 - 0.038 14.3 0.0 0.097 13.0 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Lys-AminoMut_A PF09043.11 GBG84337.1 - 0.33 9.3 0.8 0.82 8.1 0.4 1.7 2 0 0 2 2 2 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Glyco_hydro_114 PF03537.13 GBG84338.1 - 5.6e-81 271.3 0.2 6.6e-81 271.0 0.2 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 SLC12 PF03522.15 GBG84339.1 - 0.97 8.4 6.1 1.4 7.9 6.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Nop14 PF04147.12 GBG84339.1 - 1.6 6.9 31.6 1.4 7.0 30.5 1.4 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 GBG84339.1 - 1.6 8.0 33.7 2.2 7.6 33.7 1.1 1 0 0 1 1 1 0 BUD22 RT_RNaseH_2 PF17919.1 GBG84341.1 - 1e-25 89.7 0.0 1.7e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84341.1 - 3.3e-20 72.3 0.0 5.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84341.1 - 6.7e-07 29.1 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG84341.1 - 0.0075 14.6 23.5 0.013 13.8 23.5 1.5 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GBG84341.1 - 0.011 15.1 36.7 0.015 14.7 36.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG84341.1 - 0.024 12.9 35.7 0.032 12.5 35.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG84341.1 - 0.071 12.4 35.2 0.098 12.0 35.2 1.1 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 GBG84341.1 - 0.077 11.6 34.1 0.11 11.1 34.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPP4R2 PF09184.11 GBG84341.1 - 0.14 11.7 28.3 0.23 11.0 28.3 1.3 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 GBG84341.1 - 0.57 9.9 31.5 0.81 9.4 31.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SID-1_RNA_chan PF13965.6 GBG84341.1 - 0.75 8.1 2.8 0.94 7.8 2.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NOA36 PF06524.12 GBG84341.1 - 0.96 8.7 26.9 1.7 7.9 26.9 1.3 1 0 0 1 1 1 0 NOA36 protein DDHD PF02862.17 GBG84341.1 - 1.1 9.3 3.7 1.7 8.7 3.7 1.4 1 0 0 1 1 1 0 DDHD domain SpoIIIAH PF12685.7 GBG84341.1 - 3.2 7.5 18.6 5 6.9 18.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SURF2 PF05477.11 GBG84341.1 - 5.9 6.5 19.1 11 5.7 19.1 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Presenilin PF01080.17 GBG84341.1 - 8.4 5.0 18.3 12 4.5 18.3 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG84341.1 - 9 5.0 18.3 12 4.5 18.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Chromo PF00385.24 GBG84342.1 - 8.8e-13 48.0 0.0 1.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_4 PF13837.6 GBG84344.1 - 1.3e-08 35.1 0.2 5.2e-08 33.2 0.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG84345.1 - 5.8e-17 61.8 0.0 3.3e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84345.1 - 1.9e-06 27.6 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Pkinase_Tyr PF07714.17 GBG84346.1 - 5.3e-41 140.6 0.0 2.3e-40 138.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG84346.1 - 2.3e-34 119.0 0.0 3.9e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG84346.1 - 0.0095 14.8 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Lactonase PF10282.9 GBG84346.1 - 0.087 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller APH PF01636.23 GBG84346.1 - 0.16 11.8 0.0 0.62 9.9 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family GrlR PF16518.5 GBG84346.1 - 0.16 11.9 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 T3SS negative regulator,GrlR Asp_protease_2 PF13650.6 GBG84347.1 - 0.0004 21.0 0.0 0.00085 19.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84347.1 - 0.00078 20.0 0.0 0.002 18.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG84347.1 - 0.0085 16.4 0.1 0.061 13.6 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG84347.1 - 0.0089 16.1 2.0 0.016 15.2 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Rx_N PF18052.1 GBG84347.1 - 0.015 15.5 0.4 12 6.2 0.0 3.4 3 0 0 3 3 3 0 Rx N-terminal domain DUF1664 PF07889.12 GBG84347.1 - 0.11 12.5 0.8 3.9 7.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-CCHC_2 PF13696.6 GBG84347.1 - 0.17 11.7 0.9 0.36 10.7 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG84348.1 - 2.4e-33 115.5 0.1 5.4e-33 114.4 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84348.1 - 9.9e-28 96.5 0.2 2e-27 95.6 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84348.1 - 9.2e-27 93.0 0.1 2e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84348.1 - 5.6e-20 71.2 0.1 1.5e-19 69.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84348.1 - 7.2e-18 64.9 0.0 1.5e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG84348.1 - 0.0011 19.2 0.0 0.0037 17.4 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG84348.1 - 0.0016 18.2 0.7 0.0055 16.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) gag-asp_proteas PF13975.6 GBG84348.1 - 0.0025 18.3 0.0 0.0071 16.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG84348.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) TSA PF03249.13 GBG84349.1 - 0.79 8.4 8.9 0.99 8.1 8.9 1.0 1 0 0 1 1 1 0 Type specific antigen CCSAP PF15748.5 GBG84349.1 - 0.81 9.8 17.8 0.94 9.6 17.8 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4481 PF14800.6 GBG84349.1 - 1.4 8.3 6.3 1.6 8.1 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) HAUS6_N PF14661.6 GBG84349.1 - 1.7 8.2 11.8 2.1 7.9 11.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Methyltrn_RNA_4 PF09936.9 GBG84349.1 - 2.7 7.8 5.9 3.3 7.5 5.9 1.3 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase RAP1 PF07218.11 GBG84349.1 - 4.7 5.4 12.0 4.9 5.3 12.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PIEZO PF15917.5 GBG84349.1 - 5.9 6.3 14.7 7.2 6.0 14.7 1.2 1 0 0 1 1 1 0 Piezo FAM60A PF15396.6 GBG84349.1 - 7.6 6.5 10.0 9.5 6.2 10.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 GBG84350.1 - 1.7 7.4 20.1 1.9 7.1 20.1 1.0 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GBG84350.1 - 2.3 7.4 12.0 2.6 7.2 12.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.6 GBG84350.1 - 3.5 6.3 14.6 3.7 6.2 14.6 1.0 1 0 0 1 1 1 0 Raftlin DUF2828 PF11443.8 GBG84350.1 - 3.9 5.4 12.4 5.2 5.0 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RT_RNaseH_2 PF17919.1 GBG84351.1 - 1.6e-32 111.5 0.0 3.7e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84351.1 - 1.5e-30 106.4 0.3 4e-30 105.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84351.1 - 9e-29 99.9 0.1 2e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84351.1 - 6.6e-10 39.2 0.1 1.4e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG84351.1 - 1e-05 26.0 0.0 2.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84351.1 - 0.0019 18.8 0.0 0.0047 17.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Tn7_Tnp_TnsA_N PF08722.11 GBG84351.1 - 0.024 14.8 0.1 0.35 11.1 0.0 2.6 2 0 0 2 2 2 0 TnsA endonuclease N terminal Asp_protease PF09668.10 GBG84351.1 - 0.027 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease HepII_C PF18675.1 GBG84351.1 - 0.045 13.8 0.0 20 5.3 0.0 2.8 2 0 0 2 2 2 0 Heparinase II C-terminal domain DUF1758 PF05585.12 GBG84351.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Mcp5_PH PF12814.7 GBG84351.1 - 0.1 12.7 0.3 0.27 11.4 0.3 1.7 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Pex14_N PF04695.13 GBG84352.1 - 0.017 15.8 0.5 0.043 14.5 0.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Retrotrans_gag PF03732.17 GBG84352.1 - 0.11 12.8 0.4 0.81 10.0 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG84353.1 - 8.3e-21 73.9 0.0 1.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84353.1 - 4.3e-20 72.0 0.0 7.7e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84353.1 - 1.8e-09 37.8 0.0 4.4e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG84353.1 - 0.0011 18.6 0.0 0.0051 16.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG84356.1 - 1.3e-30 106.6 0.1 2.2e-30 105.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84356.1 - 2.8e-16 59.4 0.0 7.7e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84356.1 - 1.2e-08 35.1 0.0 4.2e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84356.1 - 1.2e-06 28.7 0.0 4.6e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG84356.1 - 7.2e-05 22.6 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG84356.1 - 0.0039 17.4 0.2 0.0039 17.4 0.2 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein CENP-K PF11802.8 GBG84356.1 - 0.2 11.2 2.5 0.38 10.3 2.5 1.4 1 0 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 GBG84356.1 - 0.29 11.1 12.6 0.63 10.0 12.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIF_alpha PF05793.12 GBG84357.1 - 3e-16 59.1 47.7 3.6e-16 58.9 47.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 GBG84357.1 - 0.013 14.3 24.9 0.014 14.2 24.9 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 GBG84357.1 - 0.041 12.7 15.8 0.037 12.9 15.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2052 PF09747.9 GBG84357.1 - 0.64 10.1 37.9 1.5 8.9 37.9 1.7 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AF-4 PF05110.13 GBG84357.1 - 0.74 7.8 37.3 0.8 7.7 37.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SOBP PF15279.6 GBG84357.1 - 1.6 9.2 15.6 2 8.9 15.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Mem_trans PF03547.18 GBG84357.1 - 3.2 6.1 5.2 3 6.1 5.2 1.1 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.14 GBG84357.1 - 3.5 5.8 44.9 4.8 5.4 44.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4614 PF15391.6 GBG84357.1 - 5.7 6.9 20.6 11 6.0 20.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF4551 PF15087.6 GBG84357.1 - 7.9 5.2 18.0 8.3 5.1 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FTO_NTD PF12933.7 GBG84358.1 - 0.89 8.7 7.7 1 8.6 7.7 1.3 1 1 0 1 1 1 0 FTO catalytic domain Laps PF10169.9 GBG84358.1 - 4.8 7.8 21.8 0.23 12.1 16.2 1.6 2 0 0 2 2 2 0 Learning-associated protein FAM60A PF15396.6 GBG84358.1 - 5.9 6.8 13.2 7.5 6.5 13.2 1.4 1 1 0 1 1 1 0 Protein Family FAM60A RT_RNaseH_2 PF17919.1 GBG84360.1 - 1.8e-29 101.7 0.1 4.2e-29 100.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84360.1 - 5e-26 91.0 0.3 1.5e-25 89.5 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84360.1 - 1.1e-20 73.5 0.2 3e-20 72.1 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG84360.1 - 6.8e-10 38.8 0.1 1.5e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG84360.1 - 1.8e-09 37.8 0.3 0.00022 21.4 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG84360.1 - 8.8e-05 22.6 0.0 0.00038 20.6 0.0 2.2 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG84360.1 - 0.00014 21.6 1.1 0.00029 20.7 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG84360.1 - 0.0052 17.0 7.6 0.083 13.2 0.4 4.1 4 0 0 4 4 4 2 Retrotransposon gag protein TFIIF_alpha PF05793.12 GBG84361.1 - 4.4e-47 160.9 39.7 2.1e-42 145.4 19.7 2.3 2 0 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RT_RNaseH_2 PF17919.1 GBG84361.1 - 6e-33 112.9 0.0 1.6e-32 111.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84361.1 - 6.3e-28 97.8 0.1 1.1e-27 97.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84361.1 - 2e-25 89.1 0.1 4.6e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84361.1 - 7.3e-18 64.4 0.5 1.8e-17 63.2 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84361.1 - 2.1e-06 27.9 0.1 0.0023 18.1 0.1 2.6 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG84361.1 - 0.01 16.0 0.1 0.028 14.6 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG84361.1 - 0.014 15.7 0.0 0.07 13.4 0.0 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein DUF1564 PF07600.11 GBG84361.1 - 0.06 13.0 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG84362.1 - 0.00084 19.6 0.2 0.00084 19.6 0.2 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein TcdA_TcdB PF12919.7 GBG84362.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Chromo PF00385.24 GBG84362.1 - 0.18 11.7 0.2 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG84363.1 - 1.2e-14 54.4 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG84363.1 - 7.2e-09 35.6 0.1 1.8e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF5095 PF17016.5 GBG84363.1 - 0.094 12.4 0.2 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) RVT_1 PF00078.27 GBG84364.1 - 6.8e-27 94.4 0.0 1.5e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KCNQ2_u3 PF16642.5 GBG84364.1 - 0.12 13.4 1.0 8.2 7.5 0.2 3.1 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 RVP_2 PF08284.11 GBG84365.1 - 7.9e-05 22.4 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84365.1 - 0.00021 21.9 0.0 0.00052 20.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84365.1 - 0.0018 18.8 0.0 0.0072 16.9 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG84365.1 - 0.0057 16.9 1.8 0.021 15.1 0.2 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein GSHPx PF00255.19 GBG84365.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase Retrotrans_gag PF03732.17 GBG84366.1 - 0.021 15.1 0.1 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein RAP1 PF07218.11 GBG84366.1 - 0.03 12.6 3.6 0.055 11.8 3.6 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Tnp_DNA_bind PF14706.6 GBG84366.1 - 0.062 13.2 1.4 0.21 11.5 1.4 1.9 1 0 0 1 1 1 0 Transposase DNA-binding Noelin-1 PF12308.8 GBG84366.1 - 2.4 8.2 4.6 0.95 9.5 0.5 2.4 3 0 0 3 3 3 0 Neurogenesis glycoprotein UPF0524 PF15823.5 GBG84367.1 - 0.081 12.3 0.3 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 Homez PF11569.8 GBG84369.1 - 0.054 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Asp_protease_2 PF13650.6 GBG84370.1 - 0.0031 18.1 0.0 0.0056 17.3 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG84370.1 - 0.033 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG84372.1 - 1.3e-09 38.0 0.0 4.3e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84372.1 - 2.4e-07 31.3 0.0 7.4e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84372.1 - 3.6e-05 24.2 0.0 0.00013 22.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG84372.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease LPP PF04728.13 GBG84372.1 - 1.8 9.0 0.0 1.8 9.0 0.0 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Band_3_cyto PF07565.13 GBG84372.1 - 3.2 7.5 5.4 5.8 6.6 5.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RVT_1 PF00078.27 GBG84373.1 - 6.2e-29 101.1 0.2 1.1e-28 100.3 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84373.1 - 4.6e-24 84.4 0.0 9.1e-24 83.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84373.1 - 6.5e-23 81.0 0.0 1.1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84373.1 - 4.7e-17 61.8 3.9 1.4e-16 60.3 0.5 2.9 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG84373.1 - 0.00024 21.2 0.8 0.0005 20.2 0.2 1.9 2 0 0 2 2 2 1 H2C2 zinc finger Integrin_b_cyt PF08725.11 GBG84373.1 - 0.14 11.8 0.1 0.36 10.5 0.1 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RVT_1 PF00078.27 GBG84374.1 - 7.9e-25 87.7 0.0 1.1e-23 84.0 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84374.1 - 1.5e-07 31.9 0.0 3.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84374.1 - 1.5e-06 28.7 0.0 4.3e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84374.1 - 3.9e-06 26.7 0.0 9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84374.1 - 0.00078 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG84374.1 - 0.19 12.0 10.6 0.14 12.4 0.4 4.1 3 0 0 3 3 3 0 Retrotransposon gag protein BLOC1_2 PF10046.9 GBG84374.1 - 2.5 8.5 7.7 0.54 10.6 1.7 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Retrotrans_gag PF03732.17 GBG84375.1 - 0.0019 18.4 0.4 0.023 14.9 0.0 2.7 2 1 1 3 3 3 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG84376.1 - 2.6e-14 53.1 0.1 9.2e-14 51.3 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG84376.1 - 3.8e-10 39.6 0.0 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG84376.1 - 1.2e-05 25.5 0.0 2.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG84376.1 - 0.045 14.0 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG84376.1 - 0.093 13.3 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84376.1 - 0.14 12.8 0.0 0.38 11.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG84377.1 - 2.2e-24 85.4 0.0 4.6e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84377.1 - 1.9e-21 76.3 0.0 8.5e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG84377.1 - 0.031 14.8 0.0 0.078 13.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG84377.1 - 0.037 14.3 0.1 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG84377.1 - 0.39 10.6 1.0 0.6 10.0 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG84378.1 - 3.4e-50 168.2 0.0 1.5e-23 82.7 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84378.1 - 1.3e-46 157.1 0.1 5.4e-23 81.3 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84378.1 - 4.7e-25 88.4 1.2 1.2e-24 87.1 0.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG84378.1 - 4.6e-16 58.7 0.0 1.1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Integrin_b_cyt PF08725.11 GBG84378.1 - 0.017 14.8 0.1 4.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Nif11 PF07862.11 GBG84378.1 - 0.094 13.0 0.2 0.94 9.8 0.0 2.8 2 0 0 2 2 2 0 Nif11 domain Paramyxo_ncap PF00973.19 GBG84378.1 - 2.2 7.1 3.5 3.2 6.5 3.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CLZ PF16526.5 GBG84378.1 - 4.4 7.7 6.7 2.1 8.8 0.5 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RT_RNaseH_2 PF17919.1 GBG84379.1 - 6.4e-50 167.3 0.0 2.7e-24 85.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84379.1 - 1.9e-47 161.6 1.6 4.8e-30 104.7 0.1 3.4 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84379.1 - 3.5e-47 159.0 0.0 4.2e-22 78.4 0.0 2.9 3 0 0 3 3 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84379.1 - 8.9e-10 38.5 1.1 2.1e-09 37.3 0.4 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG84379.1 - 2.1e-07 30.8 0.0 0.0001 22.1 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84379.1 - 4.6e-07 30.4 0.0 4.1e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84379.1 - 7.2e-07 29.7 0.0 3.3e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG84379.1 - 0.0001 22.1 0.0 0.00035 20.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG84379.1 - 0.052 12.7 0.7 15 4.6 0.0 3.4 3 1 0 3 3 3 0 Autophagy protein Apg17 Integrin_b_cyt PF08725.11 GBG84379.1 - 0.078 12.7 0.1 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain HalX PF08663.10 GBG84379.1 - 0.78 10.1 3.1 43 4.5 0.3 3.8 4 0 0 4 4 4 0 HalX domain RVT_1 PF00078.27 GBG84380.1 - 1.5e-25 90.1 0.0 3.2e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84380.1 - 2.4e-06 28.1 0.0 8e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84380.1 - 1.2e-05 25.8 0.0 2.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG84380.1 - 3e-05 23.8 0.0 5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG84380.1 - 0.0023 17.7 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG84380.1 - 0.035 14.4 0.2 0.21 11.9 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG84381.1 - 7.5e-32 110.6 0.5 1.6e-31 109.6 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84381.1 - 6.3e-28 96.8 0.0 1.2e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84381.1 - 1.5e-24 86.2 0.0 3e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84381.1 - 2.8e-16 59.4 0.0 9e-16 57.7 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84381.1 - 1.1e-08 35.3 0.0 2.9e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG84381.1 - 0.00048 20.3 0.0 0.0026 18.0 0.0 2.3 3 0 0 3 3 3 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG84383.1 - 4.7e-05 23.9 0.0 0.00015 22.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84383.1 - 0.00094 19.8 0.1 0.0063 17.1 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG84383.1 - 0.0039 17.0 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG84383.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG84385.1 - 1.7e-09 37.9 4.0 1.5e-08 34.9 2.6 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain CDC45 PF02724.14 GBG84385.1 - 0.041 12.2 3.9 0.089 11.1 3.9 1.5 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG84385.1 - 2.8 7.7 6.1 9.2 6.0 6.1 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-CCHC_6 PF15288.6 GBG84388.1 - 0.04 13.7 1.7 0.12 12.3 1.7 1.8 1 0 0 1 1 1 0 Zinc knuckle SprA-related PF12118.8 GBG84389.1 - 0.0017 17.5 13.0 0.0017 17.5 13.0 2.4 3 0 0 3 3 3 1 SprA-related family SCAB-Ig PF16709.5 GBG84389.1 - 0.091 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein PikAIV_N PF18605.1 GBG84390.1 - 0.001 18.6 1.3 0.14 11.7 0.7 3.2 2 0 0 2 2 2 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain PhoU PF01895.19 GBG84390.1 - 0.035 14.6 2.2 7.4 7.1 0.1 2.8 2 0 0 2 2 2 0 PhoU domain VIT PF08487.10 GBG84390.1 - 0.093 13.0 3.8 0.2 11.8 3.8 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain PI3K_1B_p101 PF10486.9 GBG84390.1 - 0.96 7.2 11.1 0.31 8.8 7.8 1.6 1 1 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 GBG84390.1 - 5.5 5.6 7.1 8.3 5.0 7.1 1.3 1 0 0 1 1 1 0 Presenilin Exo_endo_phos PF03372.23 GBG84393.1 - 1.6e-11 44.2 0.1 1.6e-11 44.2 0.1 3.8 3 1 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family zf-RanBP PF00641.18 GBG84393.1 - 3.8e-08 32.5 9.8 0.00026 20.2 0.5 3.0 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 GBG84393.1 - 0.00036 19.9 2.9 0.065 12.6 0.2 2.6 2 0 0 2 2 2 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 GBG84393.1 - 0.13 12.3 2.4 0.65 10.1 2.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_60s PF00428.19 GBG84393.1 - 2.5 8.7 11.3 0.65 10.6 1.1 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF287 PF03384.14 GBG84394.1 - 1.3 9.5 6.5 0.13 12.7 0.8 2.3 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 RVT_1 PF00078.27 GBG84395.1 - 3.9e-30 105.0 0.0 6.5e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84395.1 - 2e-29 101.6 0.0 3.1e-16 59.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84395.1 - 3e-19 69.3 0.0 7.2e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG84395.1 - 4e-09 36.2 0.0 1.1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG84396.1 - 9.1e-26 89.8 0.0 1.5e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84396.1 - 3.9e-22 78.5 0.0 1.1e-21 77.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84396.1 - 4.3e-10 39.5 0.0 7.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CPSase_L_D2 PF02786.17 GBG84400.1 - 2.4e-80 269.0 0.0 4.1e-80 268.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GBG84400.1 - 1.4e-42 144.7 0.0 2.6e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GBG84400.1 - 2.1e-38 130.7 0.0 8.6e-38 128.8 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 GBG84400.1 - 4.7e-07 29.5 0.0 1.1e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GBG84400.1 - 2.7e-05 23.8 0.0 5.7e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus AP_endonuc_2 PF01261.24 GBG84400.1 - 0.033 13.6 0.0 6.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Ribosomal_L37 PF08561.10 GBG84401.1 - 1.5e-14 54.5 6.2 1.6e-11 44.8 1.7 2.3 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 FAM163 PF15069.6 GBG84403.1 - 0.29 11.6 2.5 0.51 10.8 2.5 1.3 1 0 0 1 1 1 0 FAM163 family Prominin PF05478.11 GBG84404.1 - 0.011 13.8 2.6 0.016 13.2 2.6 1.3 1 0 0 1 1 1 0 Prominin DUF948 PF06103.11 GBG84404.1 - 0.09 13.1 1.3 0.2 11.9 1.3 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Cep57_MT_bd PF06657.13 GBG84404.1 - 0.43 11.1 14.1 0.43 11.1 7.7 3.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 COMP PF11598.8 GBG84404.1 - 0.93 10.0 7.6 2.1 8.9 7.6 1.6 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein DUF745 PF05335.13 GBG84404.1 - 0.93 9.2 8.0 2 8.1 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) IFP_35_N PF07334.13 GBG84404.1 - 2.6 8.2 14.0 8 6.6 4.3 2.9 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Tubulin PF00091.25 GBG84406.1 - 4e-66 223.0 0.0 5.5e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG84406.1 - 3.9e-51 172.5 0.1 6.1e-51 171.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GBG84406.1 - 0.034 13.8 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Tubulin domain WD40 PF00400.32 GBG84407.1 - 2.6e-15 56.6 9.2 0.00014 22.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG84407.1 - 0.0037 17.5 0.1 0.56 10.6 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L14 PF00238.19 GBG84408.1 - 1e-25 90.2 0.1 1.2e-25 90.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DDE_Tnp_4 PF13359.6 GBG84410.1 - 6.8e-07 29.1 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84410.1 - 2.7e-05 23.8 0.0 5.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein H_PPase PF03030.16 GBG84411.1 - 2.1e-143 479.3 15.9 2.5e-143 479.1 15.9 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Enolase_C PF00113.22 GBG84414.1 - 7.2e-160 531.0 0.5 9.3e-160 530.7 0.5 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GBG84414.1 - 5.1e-56 188.4 0.0 9.8e-56 187.5 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GBG84414.1 - 1.3e-10 41.3 0.0 2.5e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GBG84414.1 - 4.5e-06 26.0 0.0 9.1e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus zf-CCHC PF00098.23 GBG84416.1 - 5.7e-05 23.0 3.0 5.7e-05 23.0 3.0 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG84416.1 - 0.2 11.4 0.7 0.47 10.2 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG84416.1 - 0.78 9.6 4.1 1.8 8.5 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle ATP-synt_E PF05680.12 GBG84416.1 - 9.1 6.7 14.1 22 5.5 14.1 1.7 1 0 0 1 1 1 0 ATP synthase E chain CryBP1 PF07029.11 GBG84417.1 - 0.12 12.4 0.8 0.29 11.2 0.2 1.8 1 1 1 2 2 2 0 CryBP1 protein Herpes_pp85 PF04637.12 GBG84417.1 - 0.16 10.3 3.1 0.21 9.9 3.1 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF659 PF04937.15 GBG84418.1 - 7.4e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DDE_Tnp_4 PF13359.6 GBG84419.1 - 2.7e-26 92.1 0.0 3.5e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84419.1 - 8e-13 48.5 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84419.1 - 0.0051 16.5 0.3 0.13 11.9 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain SET PF00856.28 GBG84420.1 - 0.014 15.8 2.7 0.02 15.3 0.0 2.1 2 0 0 2 2 2 0 SET domain HBD PF18534.1 GBG84420.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Helical bundle domain FYDLN_acid PF09538.10 GBG84420.1 - 4.7 7.9 19.2 1.6 9.5 12.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4228 PF14009.6 GBG84421.1 - 0.035 14.5 1.2 0.05 14.0 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) API5 PF05918.11 GBG84421.1 - 2 7.1 6.6 3 6.6 6.6 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MCLC PF05934.11 GBG84421.1 - 2.6 6.7 8.9 3.5 6.2 8.9 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Enolase_C PF00113.22 GBG84422.1 - 6.9e-161 534.4 0.7 9e-161 534.0 0.7 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GBG84422.1 - 1.1e-55 187.4 0.0 2.3e-55 186.3 0.0 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GBG84422.1 - 2e-11 43.9 0.0 3.6e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GBG84422.1 - 2.8e-06 26.7 0.0 5.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Dimer_Tnp_hAT PF05699.14 GBG84423.1 - 0.085 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region BUD22 PF09073.10 GBG84424.1 - 0.033 13.6 23.9 0.04 13.3 23.9 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG84424.1 - 0.036 12.3 23.7 0.038 12.2 23.7 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG84424.1 - 0.23 10.9 23.7 0.24 10.8 23.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG84424.1 - 0.66 8.2 18.5 0.78 8.0 18.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG84424.1 - 1.1 8.9 20.4 1.4 8.6 20.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 GBG84424.1 - 1.6 7.3 24.4 1.7 7.1 24.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop53 PF07767.11 GBG84424.1 - 1.8 7.9 19.9 2.2 7.6 19.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) LAP1C PF05609.12 GBG84424.1 - 2.3 7.2 12.4 2.7 7.0 12.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NOA36 PF06524.12 GBG84424.1 - 3 7.1 15.5 3.9 6.7 15.5 1.2 1 0 0 1 1 1 0 NOA36 protein Plasmodium_Vir PF05795.11 GBG84424.1 - 3.4 7.0 6.1 4.7 6.5 6.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.15 GBG84424.1 - 3.4 7.1 13.1 4.3 6.8 13.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DNA_pol_phi PF04931.13 GBG84424.1 - 3.8 5.5 27.3 5 5.1 27.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 GBG84424.1 - 7.4 5.2 9.8 8.3 5.1 9.8 1.3 1 0 0 1 1 1 0 Presenilin IL1_propep PF02394.16 GBG84429.1 - 0.014 16.3 0.3 0.014 16.3 0.3 2.1 2 0 0 2 2 2 0 Interleukin-1 propeptide RT_RNaseH_2 PF17919.1 GBG84430.1 - 7.9e-31 106.1 0.0 2.3e-30 104.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84430.1 - 8.6e-31 106.4 0.1 1.9e-30 105.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84430.1 - 8.3e-18 64.3 0.5 2e-17 63.0 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG84430.1 - 2.4e-09 37.0 0.1 4.9e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG84430.1 - 1.4e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84430.1 - 1.3e-05 25.8 0.0 3.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84430.1 - 0.00033 21.2 0.5 0.001 19.5 0.0 2.2 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG84430.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG84430.1 - 0.058 13.2 0.0 1.1 9.1 0.0 2.4 2 1 0 2 2 2 0 Aspartyl protease zf-H2C2 PF09337.10 GBG84430.1 - 0.15 12.3 0.0 0.54 10.5 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Phage_lysozyme PF00959.19 GBG84430.1 - 0.22 12.0 0.9 2.4 8.7 0.0 3.0 3 0 0 3 3 3 0 Phage lysozyme RT_RNaseH_2 PF17919.1 GBG84431.1 - 8.5e-31 106.0 0.0 3.5e-30 104.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase ABC_membrane PF00664.23 GBG84431.1 - 8.7e-31 107.6 9.5 1.5e-30 106.8 9.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region RT_RNaseH PF17917.1 GBG84431.1 - 3.2e-20 72.4 0.0 2.7e-19 69.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG84431.1 - 2e-06 27.6 0.0 5.6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84431.1 - 7.1e-06 26.6 0.0 1.7e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84431.1 - 0.0013 19.3 0.1 0.0067 17.0 0.0 2.2 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG84431.1 - 0.0025 17.6 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG84431.1 - 0.0071 15.9 0.6 1.3 8.5 0.2 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TRAPP PF04051.16 GBG84431.1 - 0.024 14.4 0.1 0.052 13.3 0.1 1.5 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component RE_AlwI PF09491.10 GBG84431.1 - 2 7.1 6.5 3.5 6.3 6.5 1.3 1 0 0 1 1 1 0 AlwI restriction endonuclease ABC_tran PF00005.27 GBG84432.1 - 1.1e-13 51.9 5.2 7.3e-13 49.2 1.0 3.1 2 2 1 3 3 3 1 ABC transporter Dynamin_N PF00350.23 GBG84432.1 - 0.0033 17.5 0.5 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 GBG84432.1 - 0.043 13.4 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GBG84432.1 - 0.14 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 GBG84432.1 - 0.14 12.1 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase RVT_1 PF00078.27 GBG84433.1 - 5.5e-14 52.2 0.0 1.2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_19 PF14559.6 GBG84433.1 - 0.0014 19.1 3.2 0.056 14.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG84433.1 - 0.055 13.5 7.1 5.2 7.3 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG84433.1 - 0.095 12.9 6.5 78 3.8 0.3 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG84433.1 - 0.15 12.4 2.8 13 6.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG84433.1 - 0.65 9.9 5.2 12 5.9 0.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PET10 PF17316.2 GBG84433.1 - 0.66 9.5 2.8 0.59 9.6 0.9 1.8 2 0 0 2 2 2 0 Petite colonies protein 10 DUF3408 PF11888.8 GBG84434.1 - 0.021 15.0 3.3 0.025 14.7 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Spore_coat_CotO PF14153.6 GBG84434.1 - 0.043 13.8 6.6 0.051 13.5 6.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RPA43_OB PF17875.1 GBG84434.1 - 0.063 13.9 4.0 0.097 13.3 4.0 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RPN2_C PF18004.1 GBG84434.1 - 0.12 12.3 4.6 0.14 12.0 4.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Myc_N PF01056.18 GBG84434.1 - 0.29 11.0 6.9 0.44 10.4 6.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.16 GBG84434.1 - 0.32 10.1 6.4 0.36 10.0 6.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 GBG84434.1 - 0.46 8.7 11.6 0.57 8.4 11.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG84434.1 - 0.53 8.4 23.7 0.65 8.1 23.7 1.0 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 GBG84434.1 - 0.56 9.9 6.8 0.69 9.6 6.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Paf1 PF03985.13 GBG84434.1 - 0.67 8.9 15.5 0.76 8.7 15.5 1.1 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 GBG84434.1 - 1.5 8.2 16.2 1.7 8.0 16.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.8 GBG84434.1 - 2.1 8.6 21.6 3.1 8.0 21.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4746 PF15928.5 GBG84434.1 - 2.4 7.5 12.7 2.9 7.2 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CENP-T_N PF16171.5 GBG84434.1 - 2.6 6.9 4.0 2.8 6.8 4.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus TFIIA PF03153.13 GBG84434.1 - 3 7.7 10.3 3.3 7.6 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 GBG84434.1 - 4.8 6.4 15.2 5.5 6.2 15.2 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 GBG84434.1 - 9.3 5.5 18.8 12 5.1 18.8 1.1 1 0 0 1 1 1 0 NOA36 protein N6_N4_Mtase PF01555.18 GBG84435.1 - 3.5e-07 30.2 0.0 7.2e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 DNA methylase DUF4998 PF16389.5 GBG84436.1 - 0.039 13.5 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function PALP PF00291.25 GBG84437.1 - 3.1e-45 154.8 5.2 8.1e-40 137.1 2.2 2.3 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme PRIMA1 PF16101.5 GBG84437.1 - 0.49 10.4 14.0 1 9.4 14.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Dicty_REP PF05086.12 GBG84437.1 - 10 4.0 9.8 14 3.5 9.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LRR_4 PF12799.7 GBG84438.1 - 3.2e-18 65.5 8.3 1.4e-06 28.5 0.2 4.4 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GBG84438.1 - 3.3e-16 59.3 3.5 8.5e-06 25.4 0.4 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 GBG84438.1 - 4.6e-13 48.7 5.4 1.9e-05 24.3 0.0 3.6 3 0 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 GBG84438.1 - 0.01 15.9 7.5 5.5 7.3 0.2 5.2 4 1 1 5 5 5 1 Leucine Rich repeat LRR_5 PF13306.6 GBG84438.1 - 0.017 15.1 0.4 0.94 9.4 0.1 2.8 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 GBG84438.1 - 0.13 12.9 13.8 26 5.9 0.2 6.2 7 0 0 7 7 7 0 Leucine Rich Repeat Alpha_L_fucos PF01120.17 GBG84439.1 - 6.4e-28 98.2 0.0 1.2e-27 97.3 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-fucosidase Mesd PF10185.9 GBG84439.1 - 6.7e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor F5_F8_type_C PF00754.25 GBG84439.1 - 0.0001 22.4 0.4 0.00028 21.0 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain GHL6 PF14871.6 GBG84439.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Fzo_mitofusin PF04799.13 GBG84442.1 - 0.02 14.5 12.8 0.045 13.3 1.6 3.1 2 1 0 3 3 3 0 fzo-like conserved region Slx4 PF09494.10 GBG84442.1 - 0.1 12.6 0.2 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Slx4 endonuclease Lipoprotein_6 PF01441.19 GBG84442.1 - 0.21 11.6 8.2 0.046 13.7 1.0 2.5 2 1 0 2 2 2 0 Lipoprotein RRN3 PF05327.11 GBG84442.1 - 1.2 7.6 8.4 0.12 10.9 4.2 1.6 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Spc7 PF08317.11 GBG84442.1 - 2.7 6.8 31.8 2.7 6.8 0.2 4.2 2 1 2 4 4 4 0 Spc7 kinetochore protein DUF5403 PF17395.2 GBG84442.1 - 3.8 7.9 6.3 21 5.5 0.6 3.3 2 1 0 3 3 3 0 Family of unknown function (DUF5403) DUF2443 PF10398.9 GBG84442.1 - 7.8 6.6 6.9 53 4.0 0.1 4.3 4 2 1 5 5 5 0 Protein of unknown function (DUF2443) MatP PF06303.12 GBG84443.1 - 0.2 12.2 0.2 0.65 10.6 0.3 1.7 2 0 0 2 2 2 0 MatP N-terminal domain Myb_DNA-bind_4 PF13837.6 GBG84444.1 - 3.2e-12 46.6 0.6 3.2e-12 46.6 0.6 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG84444.1 - 0.029 14.6 0.4 0.064 13.5 0.1 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Astro_capsid_p PF12226.8 GBG84444.1 - 0.83 8.7 2.5 1.5 7.9 2.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein MADF_DNA_bdg PF10545.9 GBG84444.1 - 1.9 8.9 5.9 0.3 11.4 0.3 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3223 PF11523.8 GBG84445.1 - 3.1e-23 82.4 0.3 1e-22 80.7 0.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) CID_GANP PF16766.5 GBG84445.1 - 0.84 9.9 3.7 1.9 8.8 3.7 1.5 1 0 0 1 1 1 0 Binding region of GANP to ENY2 DUF393 PF04134.12 GBG84446.1 - 3e-26 93.0 0.6 4.8e-26 92.3 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF393 RNA_pol_Rpb2_6 PF00562.28 GBG84447.1 - 2.1e-67 227.9 0.0 9.3e-36 123.7 0.0 2.1 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 GBG84447.1 - 3.4e-27 94.4 0.0 8.8e-27 93.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 GBG84447.1 - 3.3e-19 69.1 0.1 7.7e-19 67.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 GBG84447.1 - 3.9e-19 69.0 0.0 5.6e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 GBG84447.1 - 4.7e-13 48.9 0.0 9.4e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.15 GBG84447.1 - 2.4e-12 46.8 0.0 3.5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit Nudix_N_2 PF14803.6 GBG84447.1 - 0.092 12.7 0.9 2.8 7.9 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal zf-Sec23_Sec24 PF04810.15 GBG84447.1 - 0.16 12.1 0.6 0.73 9.9 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Trimer_CC PF08954.11 GBG84448.1 - 0.023 14.3 0.2 0.059 12.9 0.2 1.7 1 0 0 1 1 1 0 Trimerisation motif Ant_C PF05586.11 GBG84448.1 - 0.059 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Anthrax receptor C-terminus region PHTB1_C PF14728.6 GBG84448.1 - 0.069 12.2 0.0 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 PTHB1 C-terminus MAD PF05557.13 GBG84449.1 - 7.4e-39 133.7 70.0 5.1e-38 130.9 70.0 2.7 1 1 0 1 1 1 1 Mitotic checkpoint protein Fez1 PF06818.15 GBG84449.1 - 0.0093 16.4 10.3 0.0093 16.4 10.3 5.6 3 2 2 5 5 5 1 Fez1 DUF1184 PF06683.11 GBG84449.1 - 3.1 7.3 6.0 7.8 5.9 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1184) MAD PF05557.13 GBG84450.1 - 1.6e-38 132.5 67.6 6e-38 130.7 66.8 2.8 1 1 0 1 1 1 1 Mitotic checkpoint protein Fez1 PF06818.15 GBG84450.1 - 0.0083 16.6 10.2 0.0083 16.6 10.2 5.6 3 2 2 5 5 5 1 Fez1 DUF1184 PF06683.11 GBG84450.1 - 3.1 7.2 6.0 7.7 6.0 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1184) RT_RNaseH_2 PF17919.1 GBG84451.1 - 2.9e-27 94.6 0.0 7.7e-27 93.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84451.1 - 3.6e-27 94.7 0.0 9.1e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RWD PF05773.22 GBG84451.1 - 2.4e-05 24.6 0.0 5.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 GBG84451.1 - 0.12 12.7 8.7 0.38 11.1 2.4 3.4 3 0 0 3 3 3 0 Ring finger domain SPOC PF07744.13 GBG84451.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 SPOC domain zf-RING_UBOX PF13445.6 GBG84451.1 - 0.52 10.4 4.5 0.19 11.8 0.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger DUF1644 PF07800.12 GBG84451.1 - 1.1 9.3 5.3 0.17 12.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) zf-rbx1 PF12678.7 GBG84451.1 - 2.2 8.6 7.5 1.2 9.5 3.3 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GBG84451.1 - 4.8 7.0 7.0 1.5 8.6 3.0 2.3 2 0 0 2 2 2 0 RING-like zinc finger MRP-S26 PF14943.6 GBG84452.1 - 0.00054 19.9 10.3 0.00068 19.6 10.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 Pox_A_type_inc PF04508.12 GBG84452.1 - 0.0079 16.0 0.2 0.13 12.1 0.2 2.7 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat KH_7 PF17214.3 GBG84453.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 KH domain Dimer_Tnp_hAT PF05699.14 GBG84455.1 - 4.6e-05 23.1 0.1 9e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase_Tyr PF07714.17 GBG84456.1 - 2.2e-34 118.9 0.0 3.7e-34 118.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG84456.1 - 5.1e-33 114.6 0.0 1.3e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 GBG84456.1 - 0.045 12.5 0.0 0.089 11.5 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase DUF659 PF04937.15 GBG84457.1 - 2.8e-27 95.4 0.0 5.1e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) MPP6 PF10175.9 GBG84457.1 - 0.26 11.8 10.8 0.028 14.9 1.9 2.5 2 0 0 2 2 2 0 M-phase phosphoprotein 6 SDA1 PF05285.12 GBG84457.1 - 0.29 10.5 18.6 0.44 9.9 18.6 1.4 1 0 0 1 1 1 0 SDA1 DUF3537 PF12056.8 GBG84457.1 - 0.35 9.6 0.0 0.35 9.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) CDC45 PF02724.14 GBG84457.1 - 2.8 6.1 17.0 3.9 5.6 17.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1115 PF06544.12 GBG84459.1 - 0.045 13.8 0.3 0.086 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) ALMT PF11744.8 GBG84459.1 - 0.16 10.8 0.2 0.19 10.5 0.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Pkinase_Tyr PF07714.17 GBG84460.1 - 3.5e-32 111.7 0.0 6.7e-32 110.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG84460.1 - 8.3e-31 107.3 0.0 1.6e-19 70.3 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG84460.1 - 0.00021 21.3 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG84460.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF2514 PF10721.9 GBG84461.1 - 0.98 9.4 6.8 1.7 8.7 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Pkinase PF00069.25 GBG84462.1 - 9.7e-37 126.7 0.0 1.3e-23 83.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84462.1 - 4.7e-35 121.1 0.0 9e-35 120.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG84462.1 - 0.00075 18.4 0.0 0.012 14.4 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GBG84462.1 - 0.031 14.2 7.6 0.024 14.5 2.5 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 GBG84463.1 - 2.1e-36 125.7 0.0 2e-22 79.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84463.1 - 2.8e-33 115.3 0.0 8.1e-16 58.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GBG84463.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 GBG84464.1 - 1.6e-27 95.5 0.0 4.4e-27 94.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84464.1 - 9.4e-26 90.1 0.1 3.6e-25 88.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84464.1 - 1.2e-08 35.2 0.0 1.2e-07 31.9 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG84464.1 - 0.0034 17.3 0.0 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HIP1_clath_bdg PF16515.5 GBG84464.1 - 0.0052 17.4 3.4 0.0052 17.4 3.4 4.3 5 0 0 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 GBG84464.1 - 0.17 12.4 1.2 0.82 10.2 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Histone PF00125.24 GBG84466.1 - 1.4e-21 77.2 0.0 1.4e-21 77.2 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG84466.1 - 0.024 15.0 0.1 0.051 14.0 0.1 1.5 1 0 0 1 1 1 0 CENP-S protein SusD_RagB PF07980.11 GBG84466.1 - 0.063 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 SusD family Pkinase_Tyr PF07714.17 GBG84467.1 - 1e-38 133.1 0.0 1.4e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG84467.1 - 4.2e-35 121.4 0.0 2.2e-23 82.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG84467.1 - 0.00047 20.1 0.1 0.0061 16.5 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Methyltransf_4 PF02390.17 GBG84468.1 - 2.1e-31 108.7 0.0 4.6e-31 107.6 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 GBG84468.1 - 2.4e-06 27.4 0.0 5.1e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG84468.1 - 3.1e-05 24.6 0.0 6.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GBG84468.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG84468.1 - 0.0058 17.4 0.0 0.015 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG84468.1 - 0.044 14.4 0.0 0.18 12.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 GBG84468.1 - 0.057 13.3 0.0 0.33 10.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GBG84468.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CoA_trans PF01144.23 GBG84468.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase Coq4 PF05019.13 GBG84469.1 - 3.1e-78 262.1 0.0 4.6e-78 261.5 0.0 1.3 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DDHD PF02862.17 GBG84469.1 - 0.099 12.8 2.2 12 6.0 0.0 2.3 2 0 0 2 2 2 0 DDHD domain RT_RNaseH_2 PF17919.1 GBG84470.1 - 5.3e-23 80.9 0.1 1e-22 80.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84470.1 - 4.5e-10 39.8 0.0 9.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG84470.1 - 1.3e-06 28.2 1.9 2.2e-06 27.5 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG84470.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG84470.1 - 0.38 10.6 2.9 0.72 9.7 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG84471.1 - 1.8e-13 50.4 0.9 7.2e-13 48.4 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG84471.1 - 2.3e-05 24.5 0.3 8.3e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger Cys_rich_CWC PF14375.6 GBG84471.1 - 0.0096 16.3 0.8 0.027 14.9 0.8 1.8 1 0 0 1 1 1 1 Cysteine-rich CWC AAA_23 PF13476.6 GBG84471.1 - 0.04 14.4 3.0 0.094 13.2 3.0 1.6 1 0 0 1 1 1 0 AAA domain Nop14 PF04147.12 GBG84472.1 - 1.5 7.0 32.1 2.1 6.5 32.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG84472.1 - 3 6.0 30.3 4.1 5.6 30.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 GBG84473.1 - 2.3 6.9 29.3 3.2 6.5 29.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BUD22 PF09073.10 GBG84473.1 - 6.5 6.0 41.7 6.9 5.9 41.7 1.0 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 GBG84473.1 - 7.8 5.2 21.5 8.5 5.0 21.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_polI_A34 PF08208.11 GBG84473.1 - 8.9 6.3 40.9 11 6.1 40.9 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Pkinase PF00069.25 GBG84474.1 - 6.3e-22 78.2 0.0 2.5e-21 76.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84474.1 - 1.4e-20 73.7 0.0 2.9e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG84474.1 - 2.4e-14 53.5 3.2 8.4e-05 23.3 0.2 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Pox_A_type_inc PF04508.12 GBG84474.1 - 1 9.3 6.6 3.8 7.5 2.2 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat NYD-SP28_assoc PF14775.6 GBG84474.1 - 4.4 7.5 5.0 29 4.9 1.6 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain FAM76 PF16046.5 GBG84474.1 - 4.8 6.4 16.1 8.8 5.6 16.1 1.4 1 0 0 1 1 1 0 FAM76 protein adh_short PF00106.25 GBG84475.1 - 1.8e-38 132.0 0.1 4.1e-30 104.7 0.1 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GBG84475.1 - 2.4e-30 105.9 0.0 3.4e-22 79.1 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG84475.1 - 1.3e-07 31.8 0.0 2.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GBG84475.1 - 0.0016 17.9 0.0 0.0052 16.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HAD_SAK_1 PF10307.9 GBG84475.1 - 0.059 13.2 0.2 0.12 12.1 0.2 1.4 1 1 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins Glyco_hydro_46 PF01374.18 GBG84477.1 - 7.5e-95 316.5 0.1 8.9e-95 316.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 zf-CCHC PF00098.23 GBG84481.1 - 2.4e-06 27.3 0.8 4.7e-06 26.4 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG84481.1 - 2e-05 24.3 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG84481.1 - 2.7e-05 24.6 0.0 7.6e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84481.1 - 0.0041 17.7 0.0 0.016 15.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG84481.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Nitr_red_bet_C PF14711.6 GBG84481.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal DUF4407 PF14362.6 GBG84483.1 - 0.013 14.8 4.6 0.016 14.6 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-Q PF13094.6 GBG84483.1 - 1.8 8.7 12.2 2.9 8.1 12.2 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Fzo_mitofusin PF04799.13 GBG84483.1 - 2.1 7.9 4.5 6.3 6.3 4.5 1.8 1 1 0 1 1 1 0 fzo-like conserved region Acylphosphatase PF00708.18 GBG84484.1 - 3.7e-17 62.5 0.1 4.3e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 Acylphosphatase gag-asp_proteas PF13975.6 GBG84485.1 - 9.9e-08 32.4 0.0 4.4e-07 30.4 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84485.1 - 3.5e-07 30.8 0.0 1.2e-06 29.1 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG84485.1 - 2.1e-06 27.6 0.0 5.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease PDEase_II PF02112.15 GBG84485.1 - 0.065 12.3 0.2 0.091 11.9 0.2 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Asp_protease PF09668.10 GBG84485.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease IBR PF01485.21 GBG84486.1 - 2.2e-21 75.8 38.6 1.7e-15 57.0 2.6 4.6 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain Stb3 PF10330.9 GBG84487.1 - 0.94 9.6 5.1 12 6.0 0.7 2.3 2 0 0 2 2 2 0 Putative Sin3 binding protein RRM_1 PF00076.22 GBG84488.1 - 1.1e-52 175.7 0.0 3e-19 68.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GBG84488.1 - 3.1e-05 23.6 0.0 0.054 13.1 0.0 3.0 2 2 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG84488.1 - 0.00034 20.4 0.0 0.4 10.6 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 GBG84488.1 - 0.0014 18.7 0.0 1.6 8.9 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif RRM_8 PF11835.8 GBG84488.1 - 0.071 13.3 0.1 4.3 7.6 0.0 3.1 2 1 1 3 3 3 0 RRM-like domain Cas_Cas2CT1978 PF09707.10 GBG84488.1 - 0.097 12.8 0.0 8.9 6.5 0.0 3.3 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) RRM_1 PF00076.22 GBG84489.1 - 5.4e-53 176.7 0.0 2.3e-19 69.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GBG84489.1 - 1.6e-05 24.5 0.0 0.039 13.6 0.0 3.0 2 2 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG84489.1 - 0.00019 21.2 0.0 0.31 10.9 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 GBG84489.1 - 0.00066 19.8 0.0 1.2 9.3 0.0 3.7 3 0 0 3 3 3 1 RNA recognition motif RRM_8 PF11835.8 GBG84489.1 - 0.041 14.1 0.1 3.2 8.0 0.0 3.1 2 1 1 3 3 3 0 RRM-like domain Cas_Cas2CT1978 PF09707.10 GBG84489.1 - 0.054 13.6 0.0 7 6.8 0.0 3.3 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) Eapp_C PF10238.9 GBG84489.1 - 4.3 7.4 6.8 7.4 6.6 0.3 2.5 3 0 0 3 3 3 0 E2F-associated phosphoprotein DUF1636 PF07845.11 GBG84489.1 - 8.4 6.9 7.2 24 5.4 1.6 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1636) Sina PF03145.16 GBG84490.1 - 1.9e-24 86.7 1.6 1.9e-24 86.7 1.6 2.0 2 0 0 2 2 2 1 Seven in absentia protein family Clat_adaptor_s PF01217.20 GBG84491.1 - 4.1e-56 188.8 0.9 4.8e-56 188.6 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FBPase PF00316.20 GBG84492.1 - 3.8e-58 196.1 0.4 5.5e-58 195.6 0.4 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain MccV PF17508.2 GBG84492.1 - 1.1 9.9 14.1 6.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Microcin V bacteriocin RT_RNaseH_2 PF17919.1 GBG84493.1 - 1.8e-25 88.9 0.0 3.1e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84493.1 - 2.3e-23 82.4 0.0 4.3e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84493.1 - 2.4e-15 56.7 0.0 3.8e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG84493.1 - 0.00017 21.5 4.6 0.00033 20.6 4.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG84493.1 - 0.16 11.9 0.1 0.4 10.7 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Na_trans_assoc PF06512.13 GBG84493.1 - 0.9 9.8 13.3 1.8 8.8 13.3 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG84493.1 - 1.4 8.3 23.7 2.2 7.6 23.7 1.2 1 0 0 1 1 1 0 SDA1 zf-CCHC_2 PF13696.6 GBG84493.1 - 1.9 8.4 6.1 3.8 7.4 6.1 1.5 1 0 0 1 1 1 0 Zinc knuckle BUD22 PF09073.10 GBG84493.1 - 6.6 6.0 27.2 11 5.3 27.2 1.2 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 GBG84493.1 - 8.8 6.6 16.0 19 5.5 16.0 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ORC4_C PF14629.6 GBG84494.1 - 4.6e-37 127.5 1.0 6.7e-37 127.0 0.1 1.7 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 GBG84494.1 - 2e-11 44.6 1.3 1.3e-10 42.0 1.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GBG84494.1 - 3.4e-09 37.2 0.0 8.3e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG84494.1 - 4.1e-08 33.6 0.1 1.1e-07 32.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GBG84494.1 - 9.4e-05 22.4 0.2 0.00021 21.2 0.2 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 GBG84494.1 - 0.0001 21.6 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 GBG84494.1 - 0.0005 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GBG84494.1 - 0.0016 17.6 0.0 0.0035 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 GBG84494.1 - 0.0051 16.8 0.3 0.032 14.2 0.3 2.2 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 GBG84494.1 - 0.0054 16.2 0.2 0.012 15.0 0.1 1.7 2 0 0 2 2 2 1 Bacterial TniB protein ATPase_2 PF01637.18 GBG84494.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 GBG84494.1 - 0.007 15.9 0.0 0.082 12.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 GBG84494.1 - 0.011 15.7 0.2 0.037 14.0 0.2 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain DAP3 PF10236.9 GBG84494.1 - 0.018 14.2 0.0 0.09 11.9 0.0 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 CDC4_D PF16856.5 GBG84494.1 - 0.032 14.1 0.2 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain AAA_5 PF07728.14 GBG84494.1 - 0.035 14.1 0.2 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GBG84494.1 - 0.12 11.7 0.0 0.47 9.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 GBG84494.1 - 0.14 11.6 0.3 10 5.5 0.0 2.5 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 GBG84494.1 - 0.2 10.8 2.6 2.7 7.1 1.7 2.7 2 1 1 3 3 3 0 G-protein alpha subunit FA_desaturase_2 PF03405.14 GBG84495.1 - 2.2e-152 506.6 0.0 2.6e-152 506.4 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 GBG84495.1 - 0.035 14.5 0.0 5.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Rubrerythrin FA_desaturase_2 PF03405.14 GBG84496.1 - 2.1e-152 506.7 0.0 2.4e-152 506.4 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 GBG84496.1 - 0.034 14.6 0.0 5.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Rubrerythrin RT_RNaseH PF17917.1 GBG84497.1 - 1.6e-25 89.4 0.0 3.5e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84497.1 - 1.4e-23 82.8 0.0 3.1e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84497.1 - 1.2e-10 41.3 0.0 2.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_4 PF12799.7 GBG84498.1 - 1.5e-09 38.0 11.7 0.0023 18.3 0.1 5.5 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG84498.1 - 3.2e-05 23.6 6.5 0.083 12.7 0.2 4.0 3 1 1 4 4 4 2 Leucine rich repeat PEPCK_ATP PF01293.20 GBG84500.1 - 9.3e-217 720.2 0.0 1.1e-216 720.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Myb_DNA-bind_4 PF13837.6 GBG84501.1 - 4.4e-06 27.0 0.2 1.2e-05 25.6 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain E1-E2_ATPase PF00122.20 GBG84501.1 - 2 7.9 7.4 4 6.9 7.4 1.5 1 0 0 1 1 1 0 E1-E2 ATPase Wzy_C PF04932.15 GBG84501.1 - 3.5 7.2 6.5 6.7 6.3 6.5 1.6 1 0 0 1 1 1 0 O-Antigen ligase Integrase_H2C2 PF17921.1 GBG84503.1 - 3.8e-18 65.3 0.4 7.1e-18 64.5 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84503.1 - 4e-16 59.3 0.0 1.1e-15 57.8 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG84503.1 - 2.5e-15 56.6 1.1 5e-15 55.7 1.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84503.1 - 1.2e-07 31.7 0.2 2.9e-07 30.5 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ABC2_membrane_3 PF12698.7 GBG84504.1 - 0.038 13.1 2.0 0.042 13.0 2.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2675 PF11247.8 GBG84505.1 - 0.08 13.1 0.1 3 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2675) DUF659 PF04937.15 GBG84506.1 - 2.9e-11 43.4 0.0 4.2e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Histone PF00125.24 GBG84507.1 - 3.1e-22 79.3 2.1 2.4e-21 76.5 0.0 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Peptidase_C14 PF00656.22 GBG84509.1 - 0.0048 16.9 1.0 0.51 10.3 0.1 2.5 2 0 0 2 2 2 2 Caspase domain zinc_ribbon_6 PF14599.6 GBG84509.1 - 0.016 15.2 12.2 2.9 8.0 0.2 5.3 5 0 0 5 5 5 0 Zinc-ribbon zf-C2H2_3rep PF18868.1 GBG84509.1 - 0.16 12.6 2.4 5.5 7.7 0.1 4.0 5 0 0 5 5 5 0 Zinc finger C2H2-type, 3 repeats TF_Zn_Ribbon PF08271.12 GBG84509.1 - 0.31 10.6 13.8 12 5.6 0.0 5.6 6 0 0 6 6 6 0 TFIIB zinc-binding Jas PF16135.5 GBG84509.1 - 0.34 11.1 22.4 8.9 6.6 0.2 6.7 7 0 0 7 7 7 0 TPL-binding domain in jasmonate signalling zf-C2H2_3 PF13878.6 GBG84509.1 - 10 6.1 20.6 24 4.9 0.2 5.9 6 0 0 6 6 6 0 zinc-finger of acetyl-transferase ESCO Integrase_H2C2 PF17921.1 GBG84511.1 - 9.6e-13 48.0 0.1 2.8e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG84511.1 - 5.1e-07 30.2 0.0 1.2e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG84511.1 - 6.2e-07 29.6 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG84511.1 - 6.4e-05 23.5 0.0 0.00026 21.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG84511.1 - 0.0044 16.8 1.0 0.01 15.6 1.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG84511.1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG84511.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG84511.1 - 0.15 12.3 0.0 0.51 10.7 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Nucleo_P87 PF07267.11 GBG84511.1 - 3.2 6.5 13.0 7.6 5.3 13.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box-like PF12937.7 GBG84515.1 - 3.4e-06 26.8 0.1 7.5e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG84515.1 - 1.6e-05 24.6 0.4 0.00031 20.5 0.2 2.5 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 GBG84515.1 - 0.023 14.7 0.5 28 5.1 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat F-box_5 PF18511.1 GBG84515.1 - 0.23 11.0 2.2 0.48 10.0 1.2 1.9 2 0 0 2 2 2 0 F-box RRN3 PF05327.11 GBG84516.1 - 0.87 8.1 5.1 0.91 8.0 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 COPI_C PF06957.11 GBG84516.1 - 1.9 7.1 10.9 2.2 7.0 10.9 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus NOA36 PF06524.12 GBG84516.1 - 3.7 6.8 22.3 5.6 6.2 22.3 1.3 1 0 0 1 1 1 0 NOA36 protein Myb_DNA-bind_4 PF13837.6 GBG84519.1 - 5.4e-05 23.5 0.6 9.5e-05 22.7 0.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG84519.1 - 0.014 15.5 0.5 0.025 14.7 0.5 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Glyco_hydro_88 PF07470.13 GBG84520.1 - 7.3e-77 258.7 0.0 8.9e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 OCRE PF17780.1 GBG84520.1 - 1 9.5 4.8 1.3 9.1 0.5 3.1 4 0 0 4 4 4 0 OCRE domain FUN14 PF04930.15 GBG84522.1 - 0.098 13.1 0.0 38 4.8 0.0 2.9 3 0 0 3 3 3 0 FUN14 family NicO PF03824.16 GBG84522.1 - 6.3 6.0 16.4 6.9 5.9 13.3 2.3 2 0 0 2 2 2 0 High-affinity nickel-transport protein Pkinase_Tyr PF07714.17 GBG84523.1 - 2.9e-11 43.1 0.0 1.7e-08 34.1 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG84523.1 - 6.6e-10 38.8 0.0 5.5e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain NHL PF01436.21 GBG84523.1 - 4.2e-05 23.4 0.0 0.14 12.2 0.1 3.4 2 0 0 2 2 2 2 NHL repeat SGL PF08450.12 GBG84523.1 - 0.00089 18.9 0.0 0.095 12.3 0.0 3.0 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Mito_fiss_reg PF05308.11 GBG84523.1 - 0.053 13.6 4.7 0.19 11.8 4.7 1.9 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 GBG84523.1 - 0.31 10.5 7.5 0.77 9.2 7.5 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG84523.1 - 2 8.5 12.4 0.46 10.5 8.4 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Co_AT_N PF12557.8 GBG84524.1 - 0.041 13.8 4.7 0.097 12.6 4.7 1.7 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Pan3_PK PF18101.1 GBG84524.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Pan3 Pseudokinase domain DDE_Tnp_4 PF13359.6 GBG84525.1 - 5.7e-22 78.1 0.0 7.2e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84525.1 - 3.8e-12 46.2 0.0 5.2e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84525.1 - 0.0074 16.0 0.0 1.7 8.2 0.1 2.2 2 0 0 2 2 2 2 Transposase DDE domain Ion_trans PF00520.31 GBG84526.1 - 5.1e-17 61.9 8.7 7.7e-17 61.3 8.7 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 GBG84526.1 - 1.8e-05 24.7 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ribosomal_S15 PF00312.22 GBG84526.1 - 0.021 15.1 0.5 0.05 13.8 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein S15 Myb_DNA-bind_4 PF13837.6 GBG84528.1 - 0.0064 16.8 0.2 0.013 15.9 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG84529.1 - 4.4e-17 62.2 0.0 6.3e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84529.1 - 1.7e-09 37.6 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein PPO1_KFDV PF12143.8 GBG84533.1 - 1.6e-08 34.7 0.0 2.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF_B2219) Myb_DNA-bind_4 PF13837.6 GBG84534.1 - 2.3e-05 24.7 0.7 3.7e-05 24.0 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG84534.1 - 0.016 15.4 1.6 0.11 12.7 1.6 2.1 1 1 0 1 1 1 0 Myb-like DNA-binding domain Senescence PF06911.12 GBG84534.1 - 0.017 15.5 0.4 0.021 15.1 0.4 1.2 1 0 0 1 1 1 0 Senescence-associated protein MADF_DNA_bdg PF10545.9 GBG84534.1 - 0.097 13.0 0.9 0.19 12.1 1.0 1.5 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG84535.1 - 8e-27 93.8 0.0 1.1e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84535.1 - 4.5e-14 52.5 0.0 6.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84535.1 - 1.3e-06 28.2 0.1 6.2e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 Transposase DDE domain SHD1 PF03983.12 GBG84535.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 RRN3 PF05327.11 GBG84535.1 - 0.73 8.3 2.7 0.96 7.9 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hexapep PF00132.24 GBG84537.1 - 4.9e-10 38.7 11.4 0.0012 18.5 0.7 3.9 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Goodbye PF17109.5 GBG84537.1 - 0.037 14.5 2.3 3.3 8.2 0.3 2.9 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain DUF963 PF06131.11 GBG84537.1 - 0.21 11.0 46.5 0.041 13.3 4.2 5.9 2 1 1 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) IMCp PF12314.8 GBG84537.1 - 0.43 10.9 17.9 0.19 12.1 13.0 2.5 1 1 2 3 3 3 0 Inner membrane complex protein DUF659 PF04937.15 GBG84539.1 - 1.9e-16 60.3 0.0 2.6e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) AlaDh_PNT_C PF01262.21 GBG84540.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain COPI_C PF06957.11 GBG84541.1 - 9.2 4.9 10.3 16 4.1 10.3 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus RT_RNaseH PF17917.1 GBG84542.1 - 4.3e-21 75.2 2.4 2e-18 66.6 0.2 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84542.1 - 3.4e-10 39.8 0.0 9.1e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84542.1 - 5.3e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG84542.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RINT1_TIP1 PF04437.13 GBG84542.1 - 0.029 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 RINT-1 / TIP-1 family DNA_pol_alpha_N PF12254.8 GBG84542.1 - 0.18 11.9 0.4 0.52 10.4 0.4 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal RVT_1 PF00078.27 GBG84544.1 - 4.6e-24 85.2 0.1 7e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84544.1 - 2.6e-14 53.1 0.0 7.5e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Vps51 PF08700.11 GBG84544.1 - 3.2e-14 52.7 0.4 1.4e-13 50.7 0.2 2.2 2 0 0 2 2 2 1 Vps51/Vps67 Asp_protease_2 PF13650.6 GBG84544.1 - 1.9e-06 28.4 0.0 4.8e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84544.1 - 2.2e-06 28.1 0.0 5.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG84544.1 - 4.7e-06 26.8 0.0 1.2e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase COG5 PF10392.9 GBG84544.1 - 0.0004 20.5 0.8 0.0004 20.5 0.8 3.2 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Myosin_tail_1 PF01576.19 GBG84544.1 - 0.0007 17.5 0.4 0.0007 17.5 0.4 2.2 2 0 0 2 2 2 1 Myosin tail RVP_2 PF08284.11 GBG84544.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84544.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Dor1 PF04124.12 GBG84544.1 - 0.0022 16.7 1.9 0.024 13.3 0.4 2.4 2 0 0 2 2 2 1 Dor1-like family CLZ PF16526.5 GBG84544.1 - 0.092 13.1 1.8 21 5.6 0.4 4.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TENA_THI-4 PF03070.16 GBG84545.1 - 0.00019 21.3 0.3 0.011 15.5 0.1 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Myb_DNA-bind_4 PF13837.6 GBG84547.1 - 8.5e-07 29.3 0.6 1.6e-06 28.4 0.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG84547.1 - 0.0013 18.8 0.4 0.0021 18.1 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Senescence PF06911.12 GBG84547.1 - 0.051 13.9 4.8 0.093 13.0 4.8 1.3 1 0 0 1 1 1 0 Senescence-associated protein Myb_DNA-binding PF00249.31 GBG84547.1 - 0.34 11.2 1.1 1.2 9.4 1.1 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG84548.1 - 4.9e-26 90.7 0.0 2.5e-25 88.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84548.1 - 4e-25 88.1 0.0 2e-24 85.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG84548.1 - 1e-07 32.5 0.0 4.3e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84548.1 - 2.2e-07 31.3 0.0 1.7e-06 28.5 0.0 2.5 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG84548.1 - 1.3e-05 25.3 0.2 7.3e-05 23.0 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG84548.1 - 2.3e-05 24.1 0.0 5.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84548.1 - 0.0019 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Exo_endo_phos PF03372.23 GBG84549.1 - 4.6e-07 29.6 0.3 1.1e-06 28.4 0.3 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1156 PF06634.12 GBG84549.1 - 0.043 13.9 0.1 0.094 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) PsbN PF02468.15 GBG84550.1 - 0.062 13.2 1.0 0.078 12.8 0.0 1.6 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF2052 PF09747.9 GBG84550.1 - 0.38 10.9 19.5 0.45 10.6 14.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) NPR3 PF03666.13 GBG84550.1 - 0.82 8.4 13.5 1.2 7.8 13.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PIN_4 PF13638.6 GBG84550.1 - 2.7 8.3 5.7 3.3 8.0 4.1 2.0 2 0 0 2 2 2 0 PIN domain Ribosomal_60s PF00428.19 GBG84551.1 - 0.059 14.0 1.1 0.2 12.2 1.1 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein UPF0184 PF03670.13 GBG84551.1 - 0.073 13.5 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) zf-CCHC PF00098.23 GBG84551.1 - 0.082 13.0 0.3 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle CCDC53 PF10152.9 GBG84551.1 - 0.62 10.5 5.0 0.45 10.9 2.9 1.8 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex CpXC PF14353.6 GBG84551.1 - 1.1 9.3 4.6 1.6 8.8 0.0 2.8 3 0 0 3 3 3 0 CpXC protein DUF3391 PF11871.8 GBG84551.1 - 1.4 9.5 6.1 0.23 12.0 1.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DDE_Tnp_4 PF13359.6 GBG84552.1 - 2.2e-28 98.9 0.0 6.3e-28 97.4 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84552.1 - 9.2e-15 54.8 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84552.1 - 0.14 11.8 0.2 3.7 7.1 0.2 2.3 2 1 0 2 2 2 0 Transposase DDE domain RVT_1 PF00078.27 GBG84554.1 - 4.3e-29 101.6 0.1 6.5e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RanBP PF00641.18 GBG84555.1 - 2.3e-22 78.0 23.1 2.6e-08 33.1 3.6 3.1 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others TackOD1 PF18551.1 GBG84555.1 - 9.2 5.9 15.3 0.14 11.9 0.8 2.9 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 NAD_binding_1 PF00175.21 GBG84558.1 - 3.5 8.3 7.2 21 5.8 0.1 2.8 2 1 1 3 3 3 0 Oxidoreductase NAD-binding domain Vfa1 PF08432.10 GBG84558.1 - 8 6.7 16.1 9.6 6.5 15.2 1.5 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-CCHC PF00098.23 GBG84559.1 - 3.8e-06 26.7 3.5 6.9e-06 25.9 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Tup_N PF08581.10 GBG84559.1 - 0.00025 21.3 1.0 0.00025 21.3 1.0 2.9 2 1 1 3 3 3 1 Tup N-terminal DUF1943 PF09172.11 GBG84559.1 - 0.0059 15.9 2.9 0.009 15.3 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) Eapp_C PF10238.9 GBG84559.1 - 0.052 13.6 3.6 0.09 12.8 3.6 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein RRN3 PF05327.11 GBG84559.1 - 0.091 11.3 6.5 0.11 11.1 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Med26_C PF15693.5 GBG84559.1 - 0.19 11.9 3.9 0.25 11.5 3.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal zf-CCHC_4 PF14392.6 GBG84559.1 - 0.34 10.7 1.2 0.93 9.3 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Gon7 PF08738.10 GBG84559.1 - 0.42 10.7 5.9 0.65 10.1 4.8 1.9 1 1 1 2 2 2 0 Gon7 family Allexi_40kDa PF05549.11 GBG84559.1 - 0.61 9.6 3.5 4.4 6.7 3.3 2.0 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF4661 PF15576.6 GBG84559.1 - 0.66 9.8 6.1 0.87 9.5 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) CAF1 PF04857.20 GBG84559.1 - 1.4 8.0 4.9 1.8 7.7 4.9 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease EIIBC-GUT_N PF03612.14 GBG84559.1 - 1.4 8.6 6.2 2.3 7.9 6.2 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4972 PF16342.5 GBG84559.1 - 2.1 8.1 10.3 0.11 12.1 1.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4972) AIF_C PF14721.6 GBG84559.1 - 2.4 8.5 5.1 4.5 7.6 5.1 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Holin_BhlA PF10960.8 GBG84559.1 - 2.6 8.1 11.4 0.55 10.2 6.4 2.5 2 1 0 3 3 2 0 BhlA holin family LMBR1 PF04791.16 GBG84559.1 - 8.7 5.1 6.4 9.8 5.0 6.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.9 GBG84559.1 - 9 5.3 10.2 11 5.0 10.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Paf67 PF10255.9 GBG84560.1 - 3.9e-153 510.2 3.5 3.9e-153 510.2 3.5 1.3 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 GBG84560.1 - 0.01 15.9 0.7 0.36 11.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DDRGK PF09756.9 GBG84560.1 - 0.33 10.5 3.8 0.48 10.0 2.4 1.9 2 0 0 2 2 2 0 DDRGK domain RVT_1 PF00078.27 GBG84562.1 - 1.1e-24 87.2 0.0 2.1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84562.1 - 7.4e-23 80.5 0.0 7.7e-22 77.2 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84562.1 - 3.7e-15 56.1 0.0 4.7e-14 52.6 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84562.1 - 2.8e-10 40.4 0.0 1.1e-09 38.5 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG84562.1 - 8.9e-09 35.2 0.0 8.3e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84562.1 - 4.8e-08 33.5 0.0 1.3e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease TSP_1 PF00090.19 GBG84562.1 - 2.5e-07 30.8 12.5 0.00086 19.5 1.3 3.6 3 0 0 3 3 3 2 Thrombospondin type 1 domain gag-asp_proteas PF13975.6 GBG84562.1 - 2.7e-06 27.8 0.0 9.4e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG84562.1 - 0.0057 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF1664 PF07889.12 GBG84562.1 - 0.0059 16.6 0.6 0.023 14.7 0.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 GBG84562.1 - 1.5 9.3 4.8 65 4.0 0.4 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) zf-CCHC PF00098.23 GBG84563.1 - 0.006 16.6 0.7 0.011 15.8 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle PA26 PF04636.13 GBG84563.1 - 0.12 11.2 6.7 0.013 14.4 1.6 1.7 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) U3_snoRNA_assoc PF08297.11 GBG84563.1 - 8.9 7.1 21.4 1 10.1 11.8 2.4 2 0 0 2 2 2 0 U3 snoRNA associated RT_RNaseH_2 PF17919.1 GBG84564.1 - 2.9e-32 110.7 0.0 5.7e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84564.1 - 3.9e-30 105.0 0.1 6.3e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84564.1 - 2e-29 102.0 0.0 3.9e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_S8 PF00082.22 GBG84564.1 - 4.1e-19 69.0 0.8 6e-10 38.9 0.0 3.2 2 1 1 3 3 3 3 Subtilase family zf-CCHC PF00098.23 GBG84564.1 - 1.9e-07 30.8 1.2 4.1e-07 29.8 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG84564.1 - 0.0049 16.6 0.0 0.065 13.0 0.0 2.6 3 0 0 3 3 3 1 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GBG84564.1 - 0.1 12.4 1.6 0.22 11.4 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Peptidase_C14 PF00656.22 GBG84565.1 - 5.6e-27 95.3 0.0 1.5e-26 93.9 0.0 1.6 1 1 0 1 1 1 1 Caspase domain Evr1_Alr PF04777.13 GBG84565.1 - 5.1e-23 81.4 0.6 9e-23 80.6 0.6 1.4 1 0 0 1 1 1 1 Erv1 / Alr family RVT_1 PF00078.27 GBG84566.1 - 1.7e-14 53.9 0.0 2.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG84566.1 - 0.0015 18.8 27.8 0.12 12.6 12.2 2.3 2 0 0 2 2 2 2 Sodium ion transport-associated RasGAP PF00616.19 GBG84566.1 - 0.02 14.6 0.4 0.02 14.6 0.4 2.1 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase DUF4746 PF15928.5 GBG84566.1 - 0.12 11.8 34.9 0.18 11.2 13.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RNA_pol_Rpc4 PF05132.14 GBG84566.1 - 1.2 9.6 14.8 3.5 8.0 3.2 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 NPR3 PF03666.13 GBG84566.1 - 5.1 5.8 17.7 0.5 9.1 3.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 WRW PF10206.9 GBG84567.1 - 0.17 12.3 2.0 0.25 11.7 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Peptidase_S8 PF00082.22 GBG84568.1 - 9.5e-06 25.1 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Subtilase family IL34 PF15036.6 GBG84569.1 - 0.036 14.1 0.4 0.036 14.1 0.4 1.6 2 0 0 2 2 2 0 Interleukin 34 DUF3138 PF11336.8 GBG84569.1 - 0.11 11.1 2.4 0.17 10.5 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RT_RNaseH_2 PF17919.1 GBG84570.1 - 7.8e-31 106.1 0.0 1.7e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84570.1 - 1.1e-30 106.8 0.1 2.1e-30 105.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84570.1 - 3.6e-27 94.7 0.1 8.4e-27 93.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84570.1 - 5.1e-17 62.2 0.0 1.5e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG84570.1 - 2.5e-14 53.1 0.2 6e-14 51.9 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG84570.1 - 5.2e-06 26.3 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG84570.1 - 0.00019 21.6 0.0 0.00063 19.9 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG84570.1 - 0.00021 21.8 0.0 0.00047 20.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84570.1 - 0.00089 19.9 0.0 0.0019 18.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG84570.1 - 0.0024 17.7 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Phage_GPO PF05929.11 GBG84570.1 - 0.13 11.8 3.4 6 6.4 2.1 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2040 PF09745.9 GBG84570.1 - 0.16 12.1 3.2 5.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) GCN5L1 PF06320.13 GBG84570.1 - 0.54 10.4 7.1 0.29 11.3 4.5 1.9 2 0 0 2 2 1 0 GCN5-like protein 1 (GCN5L1) YabA PF06156.13 GBG84570.1 - 0.85 10.3 2.6 1.8 9.2 0.0 2.7 3 0 0 3 3 3 0 Initiation control protein YabA Tom22 PF04281.13 GBG84570.1 - 9.9 6.0 6.9 0.36 10.6 0.1 2.1 2 0 0 2 2 1 0 Mitochondrial import receptor subunit Tom22 Nop14 PF04147.12 GBG84571.1 - 0.56 8.4 22.9 0.63 8.2 22.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG84571.1 - 1.1 8.6 27.1 1.4 8.2 27.1 1.1 1 0 0 1 1 1 0 SDA1 DUF2201_N PF13203.6 GBG84571.1 - 1.6 8.3 7.5 2.2 7.8 7.5 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain BUD22 PF09073.10 GBG84571.1 - 1.6 8.0 22.9 2.3 7.5 22.9 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG84571.1 - 1.8 6.8 16.8 2.4 6.4 16.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG84571.1 - 3.8 7.0 12.4 5 6.6 12.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAPS PF04499.15 GBG84571.1 - 5.6 5.6 7.7 6.1 5.5 7.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Integrase_H2C2 PF17921.1 GBG84572.1 - 2.4e-18 66.0 0.3 5e-18 65.0 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG84572.1 - 8.6e-18 64.6 0.0 2.4e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84572.1 - 3.3e-14 53.1 0.0 9.8e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG84572.1 - 1.2e-11 44.5 0.0 8e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG84572.1 - 0.00035 20.5 0.2 0.00095 19.1 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF1564 PF07600.11 GBG84572.1 - 0.18 11.5 0.1 0.72 9.5 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) zf-CCHC PF00098.23 GBG84572.1 - 2.3 8.4 3.7 5.6 7.2 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle TSP_1 PF00090.19 GBG84573.1 - 0.001 19.2 1.1 0.001 19.2 1.1 1.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain TSP_1 PF00090.19 GBG84574.1 - 0.001 19.2 1.1 0.001 19.2 1.1 1.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain EGF_2 PF07974.13 GBG84575.1 - 7.1e-05 23.1 12.1 7.1e-05 23.1 12.1 4.4 4 1 0 4 4 4 1 EGF-like domain DUF1068 PF06364.12 GBG84575.1 - 0.044 13.7 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF4256 PF14066.6 GBG84575.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) RT_RNaseH_2 PF17919.1 GBG84576.1 - 1.9e-31 108.1 0.0 4.7e-31 106.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84576.1 - 7e-31 107.5 0.0 1.2e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84576.1 - 7.3e-28 96.9 0.2 1.8e-27 95.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG84576.1 - 0.014 15.4 0.6 0.028 14.4 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG84576.1 - 0.016 15.5 0.1 0.062 13.6 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG84576.1 - 0.017 15.2 5.6 0.03 14.4 5.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG84576.1 - 0.042 13.6 0.9 0.093 12.5 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle MIR PF02815.19 GBG84577.1 - 5.1e-19 68.8 3.7 4.2e-16 59.3 2.0 3.0 1 1 1 2 2 2 2 MIR domain Cofilin_ADF PF00241.20 GBG84579.1 - 5.1e-38 129.6 0.3 5.7e-38 129.4 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Poxvirus_B22R PF04395.12 GBG84579.1 - 0.066 12.7 0.2 0.071 12.6 0.2 1.3 1 1 0 1 1 1 0 Poxvirus B22R protein DNA_pol_E_B PF04042.16 GBG84580.1 - 1.7e-43 148.5 0.0 3.3e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 GBG84580.1 - 6.5e-43 146.0 0.0 1.7e-42 144.6 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain RVT_1 PF00078.27 GBG84580.1 - 7.6e-33 113.9 0.0 1.2e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TCR PF03638.15 GBG84583.1 - 1.8e-20 72.9 58.5 4.5e-11 42.9 21.0 2.5 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Presenilin PF01080.17 GBG84583.1 - 0.76 8.5 3.3 1.2 7.8 3.3 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 GBG84583.1 - 4.3 7.2 18.1 0.27 11.2 12.4 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 GBG84583.1 - 6.3 7.4 9.1 35 5.0 7.5 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM60A PF15396.6 GBG84584.1 - 0.14 12.2 4.7 0.17 11.9 4.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Ran_BP1 PF00638.18 GBG84586.1 - 2.8e-18 66.4 0.0 5.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 GBG84586.1 - 4.7e-13 49.6 1.0 4.7e-13 49.6 1.0 5.7 5 1 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) Peptidase_M3 PF01432.20 GBG84590.1 - 1.5e-95 321.2 0.1 2.2e-95 320.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 GBG84590.1 - 0.093 12.4 0.4 0.16 11.6 0.4 1.3 1 0 0 1 1 1 0 Peptidase M50B-like RVT_1 PF00078.27 GBG84591.1 - 9e-35 120.2 0.1 1.8e-34 119.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84591.1 - 2.1e-31 107.9 0.0 4.6e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84591.1 - 1.4e-27 96.0 0.1 3.6e-27 94.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84591.1 - 3.7e-15 56.2 0.0 8.6e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG84591.1 - 1.2e-06 28.3 0.0 2.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG84591.1 - 3e-05 24.6 0.0 0.00014 22.5 0.0 2.2 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84591.1 - 0.00012 22.5 0.0 0.00063 20.3 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG84591.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CCD48 PF15799.5 GBG84591.1 - 0.0014 17.0 1.8 0.0022 16.4 1.8 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 Rhamno_transf PF11316.8 GBG84591.1 - 0.057 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative rhamnosyl transferase CCDC85 PF10226.9 GBG84591.1 - 0.099 12.3 0.2 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 CCDC85 family HALZ PF02183.18 GBG84591.1 - 0.33 11.2 3.2 0.84 9.9 3.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper MIP PF00230.20 GBG84595.1 - 6.3e-14 52.2 15.0 7.5e-14 52.0 15.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein YtxH PF12732.7 GBG84595.1 - 0.0097 16.4 2.0 0.022 15.3 2.0 1.7 1 0 0 1 1 1 1 YtxH-like protein rve PF00665.26 GBG84597.1 - 4.9e-10 39.6 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG84597.1 - 8.4e-08 32.5 0.0 7.5e-07 29.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84597.1 - 2e-06 27.8 0.0 5.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG84597.1 - 0.013 15.2 0.0 0.045 13.5 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG84597.1 - 0.017 15.4 0.1 0.066 13.5 0.0 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein DUF1664 PF07889.12 GBG84597.1 - 0.18 11.9 0.8 2.5 8.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-CCHC_2 PF13696.6 GBG84597.1 - 0.23 11.3 0.9 0.39 10.6 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG84597.1 - 0.24 11.3 0.7 0.53 10.2 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG84597.1 - 0.4 10.8 2.0 0.75 10.0 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG84598.1 - 7.5e-07 29.4 1.5 1.3e-06 28.7 1.5 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG84598.1 - 0.0012 19.0 2.1 0.0026 17.9 2.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain RVT_1 PF00078.27 GBG84599.1 - 3.9e-45 154.1 0.3 2.4e-25 89.4 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84599.1 - 2.9e-31 107.9 0.1 2.6e-17 63.0 0.0 3.5 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84599.1 - 3e-23 81.7 0.0 7.3e-19 67.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84599.1 - 2.1e-16 59.8 0.2 4.3e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG84599.1 - 1.1e-05 25.6 0.1 0.079 13.2 0.0 3.2 2 0 0 2 2 2 2 Retrotransposon gag protein Integrin_b_cyt PF08725.11 GBG84599.1 - 0.026 14.2 0.0 10 5.9 0.0 2.6 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain RVP_2 PF08284.11 GBG84599.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG84599.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger NIF3 PF01784.18 GBG84600.1 - 0.017 14.7 4.5 1.5 8.4 1.3 2.4 2 1 0 2 2 2 0 NIF3 (NGG1p interacting factor 3) DHquinase_II PF01220.19 GBG84600.1 - 0.038 13.7 0.5 5.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Dehydroquinase class II Striatin PF08232.12 GBG84600.1 - 0.04 14.5 22.6 0.14 12.7 2.1 3.4 3 0 0 3 3 3 0 Striatin family Folate_carrier PF01770.18 GBG84600.1 - 4.2 6.0 6.2 15 4.2 0.3 2.3 2 0 0 2 2 2 0 Reduced folate carrier MAS20 PF02064.15 GBG84600.1 - 7.5 6.7 25.9 8.3 6.5 4.5 4.4 4 0 0 4 4 4 0 MAS20 protein import receptor Longin PF13774.6 GBG84600.1 - 9.9 6.3 6.8 32 4.6 0.1 3.2 3 1 0 3 3 3 0 Regulated-SNARE-like domain Nop14 PF04147.12 GBG84602.1 - 6.7 4.8 39.4 7.3 4.7 39.4 1.0 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 GBG84602.1 - 6.8 6.8 11.3 7.5 6.6 11.3 1.1 1 0 0 1 1 1 0 DDHD domain Cgr1 PF03879.14 GBG84603.1 - 5.3e-05 23.5 9.5 5.3e-05 23.5 9.5 2.4 2 0 0 2 2 2 1 Cgr1 family DUF5320 PF17253.2 GBG84603.1 - 2.8 9.1 14.2 14 6.8 0.4 3.8 2 1 2 4 4 4 0 Family of unknown function (DUF5320) Myb_DNA-bind_4 PF13837.6 GBG84604.1 - 0.00083 19.7 8.3 0.0024 18.2 7.2 2.2 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Presenilin PF01080.17 GBG84604.1 - 2.5 6.7 13.5 4.7 5.9 13.5 1.3 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 GBG84604.1 - 3.3 6.6 12.2 5.8 5.8 12.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 EBV-NA1 PF02905.14 GBG84605.1 - 0.095 12.5 0.4 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain DDHD PF02862.17 GBG84605.1 - 0.64 10.1 5.7 1.1 9.4 0.4 2.3 2 0 0 2 2 2 0 DDHD domain FAM176 PF14851.6 GBG84605.1 - 0.98 9.1 6.6 3.4 7.3 6.6 1.9 1 0 0 1 1 1 0 FAM176 family WRNPLPNID PF15017.6 GBG84605.1 - 2.1 9.3 7.6 7.4 7.5 7.6 1.9 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box SpoIIP PF07454.11 GBG84605.1 - 2.2 7.7 9.3 4 6.8 9.3 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 GBG84605.1 - 3.1 7.9 12.4 0.062 13.4 5.0 2.0 2 1 1 3 3 3 0 E2F-associated phosphoprotein Ureide_permease PF07168.11 GBG84605.1 - 3.9 6.1 7.4 12 4.5 7.4 1.7 1 1 0 1 1 1 0 Ureide permease Sgf11 PF08209.11 GBG84606.1 - 0.018 14.6 3.0 0.018 14.6 3.0 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) SCA7 PF08313.12 GBG84606.1 - 0.48 10.4 2.5 1.5 8.8 0.1 2.6 3 0 0 3 3 3 0 SCA7, zinc-binding domain eIF2_C PF09173.11 GBG84607.1 - 8.3e-36 122.1 0.7 2.2e-35 120.8 0.7 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 GBG84607.1 - 2.2e-24 86.1 0.4 1.5e-23 83.3 0.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GBG84607.1 - 1.8e-11 44.3 0.6 3.8e-11 43.2 0.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG84607.1 - 0.0047 17.0 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 GBG84607.1 - 0.019 14.9 0.2 0.059 13.4 0.2 1.8 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 GBG84607.1 - 0.024 14.5 0.3 0.33 10.8 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase DDR_swiveling PF18427.1 GBG84607.1 - 0.09 12.8 1.0 0.2 11.7 1.0 1.5 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain O-FucT PF10250.9 GBG84608.1 - 4.4e-72 243.6 0.0 5.7e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Myb_DNA-bind_4 PF13837.6 GBG84610.1 - 2.7e-09 37.3 0.4 4.7e-09 36.5 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG84610.1 - 0.0016 18.6 0.8 0.003 17.7 0.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG84610.1 - 0.035 14.3 0.4 0.076 13.3 0.4 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG84610.1 - 0.051 13.6 1.7 0.083 13.0 1.7 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG84610.1 - 0.068 13.5 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TPR_MLP1_2 PF07926.12 GBG84611.1 - 4.9 7.2 10.1 0.4 10.7 4.6 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RT_RNaseH_2 PF17919.1 GBG84612.1 - 3.5e-60 200.2 0.4 7.3e-31 106.2 0.0 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84612.1 - 4e-50 168.5 0.2 3.9e-23 81.7 0.0 3.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84612.1 - 7.2e-25 87.8 0.1 1.4e-24 86.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG84612.1 - 4.4e-20 71.5 0.1 1e-19 70.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG84612.1 - 1.3e-10 41.8 0.0 8.9e-07 29.5 0.0 3.0 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG84612.1 - 3e-08 33.5 0.0 8.9e-06 25.5 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG84612.1 - 5.7e-08 33.2 0.0 7.4e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TFIIA PF03153.13 GBG84612.1 - 2e-06 28.1 23.0 2e-06 28.1 23.0 2.8 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 GBG84612.1 - 0.00056 19.4 48.6 0.00056 19.4 48.6 2.0 3 0 0 3 3 1 1 DNA polymerase subunit Cdc27 Asp_protease PF09668.10 GBG84612.1 - 0.00095 19.0 0.0 0.058 13.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.10 GBG84612.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Endostatin PF06482.11 GBG84612.1 - 0.62 9.5 14.8 0.085 12.3 9.2 2.4 2 1 0 2 2 2 0 Collagenase NC10 and Endostatin Pescadillo_N PF06732.11 GBG84613.1 - 3.3e-112 374.5 1.5 5e-112 373.9 0.4 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 GBG84613.1 - 1.9e-06 28.2 0.0 4.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GBG84613.1 - 0.00074 19.8 0.0 0.0079 16.6 0.0 2.4 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GBG84613.1 - 0.029 14.6 0.0 0.11 12.8 0.0 2.1 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DUF2201_N PF13203.6 GBG84613.1 - 0.049 13.2 0.1 0.049 13.2 0.1 3.2 2 2 0 3 3 3 0 Putative metallopeptidase domain RPN2_C PF18004.1 GBG84613.1 - 0.18 11.7 0.1 0.18 11.7 0.1 4.3 2 2 2 4 4 4 0 26S proteasome regulatory subunit RPN2 C-terminal domain DDHD PF02862.17 GBG84613.1 - 3.5 7.7 9.2 8.1 6.5 4.4 2.5 2 0 0 2 2 2 0 DDHD domain Pkinase PF00069.25 GBG84615.1 - 8.1e-48 163.1 0.0 1.1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84615.1 - 3e-45 154.5 0.0 4.7e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG84615.1 - 0.0093 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GBG84615.1 - 0.12 11.3 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain ABC1 PF03109.16 GBG84615.1 - 0.22 11.7 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.25 GBG84616.1 - 8.2e-48 163.1 0.0 1.1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84616.1 - 3e-45 154.5 0.0 4.7e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG84616.1 - 0.0094 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GBG84616.1 - 0.12 11.3 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 GBG84617.1 - 1.1e-32 113.4 0.0 1.6e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG84617.1 - 1.3e-29 103.4 0.0 1.9e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DAP10 PF07213.11 GBG84617.1 - 0.1 12.6 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 DAP10 membrane protein EphA2_TM PF14575.6 GBG84617.1 - 0.22 12.4 0.8 0.64 10.9 0.1 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Sacchrp_dh_NADP PF03435.18 GBG84618.1 - 4.9e-14 52.7 0.1 8e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GBG84618.1 - 1.9e-05 24.6 0.5 3.4e-05 23.8 0.5 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GBG84618.1 - 0.0001 21.9 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GBG84618.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1232 PF06803.12 GBG84619.1 - 1.1e-05 25.2 0.2 2.3e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) DUF3021 PF11457.8 GBG84619.1 - 0.11 12.8 2.6 0.18 12.1 2.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) REGB_T4 PF10715.9 GBG84620.1 - 0.047 13.9 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB DDE_Tnp_4 PF13359.6 GBG84621.1 - 1.2e-21 77.0 0.0 1.9e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84621.1 - 5.5e-15 55.5 0.0 1.6e-14 54.0 0.0 1.6 1 1 0 1 1 1 1 Plant transposon protein Sacchrp_dh_NADP PF03435.18 GBG84622.1 - 3e-14 53.4 0.1 5.3e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GBG84622.1 - 1e-05 25.5 0.4 2e-05 24.6 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GBG84622.1 - 5.1e-05 22.9 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GBG84622.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RVT_1 PF00078.27 GBG84623.1 - 7.3e-32 110.7 0.1 1.3e-31 109.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84623.1 - 1.3e-20 73.3 2.3 3.2e-13 49.6 0.0 3.2 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84623.1 - 1.5e-17 63.8 5.1 1e-14 54.6 3.0 3.1 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84623.1 - 1.5e-16 60.2 0.3 3.4e-16 59.1 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84623.1 - 3.8e-15 56.1 0.0 1.2e-14 54.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG84623.1 - 0.0035 17.5 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF3863 PF12979.7 GBG84623.1 - 0.045 12.6 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Retrotrans_gag PF03732.17 GBG84623.1 - 0.1 12.9 0.0 0.37 11.1 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein DUF5095 PF17016.5 GBG84623.1 - 0.19 11.4 0.1 0.34 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) DNA_pol_B PF00136.21 GBG84624.1 - 1.6e-147 491.9 0.0 2.4e-147 491.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GBG84624.1 - 1.8e-81 273.9 0.0 4.5e-81 272.6 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GBG84624.1 - 5.5e-18 65.2 9.4 1.1e-17 64.2 9.4 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 GBG84624.1 - 6.3e-05 22.0 0.1 0.00016 20.7 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral zf-ribbon_3 PF13248.6 GBG84624.1 - 0.14 11.6 1.8 0.33 10.4 1.8 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DUF678 PF05077.12 GBG84624.1 - 0.39 10.9 2.6 1.4 9.1 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DnaJ_CXXCXGXG PF00684.19 GBG84624.1 - 5.1 7.5 8.3 15 6.0 8.3 1.9 1 0 0 1 1 1 0 DnaJ central domain Sacchrp_dh_NADP PF03435.18 GBG84625.1 - 1.5e-14 54.4 0.4 2.4e-14 53.7 0.4 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GBG84625.1 - 5.3e-06 26.4 0.7 8e-06 25.9 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GBG84625.1 - 7.7e-05 22.3 0.2 0.00015 21.3 0.2 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GBG84625.1 - 0.0075 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GBG84625.1 - 0.068 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 GBG84625.1 - 0.097 13.1 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GBG84626.1 - 2.1e-14 53.9 0.5 3.3e-14 53.2 0.5 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GBG84626.1 - 4.5e-06 26.7 0.7 7.3e-06 26.0 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GBG84626.1 - 6.4e-05 22.5 0.3 0.0001 21.8 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GBG84626.1 - 0.006 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GBG84626.1 - 0.1 12.0 0.1 0.25 10.8 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 GBG84626.1 - 0.16 12.4 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TLD PF07534.16 GBG84627.1 - 1.5e-38 132.2 0.1 2.3e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 TLD BSP_II PF05432.11 GBG84627.1 - 1.1 8.9 19.2 3.9 7.1 4.0 2.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF3408 PF11888.8 GBG84627.1 - 1.9 8.6 7.8 2.4 8.3 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF2052 PF09747.9 GBG84627.1 - 4.2 7.5 13.2 9.1 6.3 3.5 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Myc_N PF01056.18 GBG84627.1 - 4.6 7.1 10.4 10 5.9 0.9 2.4 2 0 0 2 2 2 0 Myc amino-terminal region RXT2_N PF08595.11 GBG84627.1 - 7.5 6.6 9.1 7.2 6.6 0.0 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 GBG84627.1 - 9 5.9 10.6 2.9 7.6 2.3 2.3 2 0 0 2 2 2 0 FAM176 family polyprenyl_synt PF00348.17 GBG84628.1 - 7e-26 90.8 0.0 1e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase RT_RNaseH_2 PF17919.1 GBG84629.1 - 1.8e-25 88.8 0.0 2.5e-24 85.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84629.1 - 4e-18 65.3 0.2 9.2e-18 64.1 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG84629.1 - 1.7e-11 44.3 0.0 7.3e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84629.1 - 3.5e-11 43.3 0.0 1.2e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG84629.1 - 8.1e-11 41.9 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG84629.1 - 0.0032 17.6 0.0 0.0096 16.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG84629.1 - 0.0034 17.3 1.9 0.0092 15.9 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Chromo PF00385.24 GBG84629.1 - 0.0038 17.1 0.1 0.92 9.5 0.0 2.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 GBG84629.1 - 0.15 11.9 0.1 0.65 9.8 0.1 2.2 1 0 0 1 1 1 0 Integrase core domain PsbY PF06298.11 GBG84630.1 - 3.2e-51 170.9 28.0 9.8e-13 47.8 0.8 4.5 4 0 0 4 4 4 4 Photosystem II protein Y (PsbY) DUF2497 PF10691.9 GBG84630.1 - 0.02 15.3 0.1 15 6.1 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2497) PBECR2 PF18810.1 GBG84630.1 - 0.037 14.3 0.0 39 4.6 0.0 3.9 4 0 0 4 4 4 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 LapA_dom PF06305.11 GBG84630.1 - 0.43 10.4 10.8 1 9.2 0.0 4.3 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain DUF5065 PF16723.5 GBG84630.1 - 8.5 6.4 15.7 1.3 9.1 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5065) RT_RNaseH PF17917.1 GBG84631.1 - 4.3e-20 72.0 0.0 9.7e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84631.1 - 7.3e-19 67.7 0.0 1.4e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAM176 PF14851.6 GBG84631.1 - 1.7 8.3 6.2 0.65 9.7 1.9 2.2 2 0 0 2 2 2 0 FAM176 family RXLR PF16810.5 GBG84631.1 - 5.5 7.4 5.3 21 5.5 1.5 2.3 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity RBFA PF02033.18 GBG84632.1 - 8e-26 90.5 0.2 1.2e-25 90.0 0.2 1.2 1 0 0 1 1 1 1 Ribosome-binding factor A AAA PF00004.29 GBG84633.1 - 2.8e-42 144.3 0.0 5.4e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RVT_1 PF00078.27 GBG84633.1 - 8.8e-22 77.7 0.0 1.6e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MIT PF04212.18 GBG84633.1 - 9.5e-19 67.2 6.3 9.5e-19 67.2 6.3 2.8 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain RT_RNaseH_2 PF17919.1 GBG84633.1 - 7.7e-12 45.1 0.0 2.6e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG84633.1 - 2.3e-06 28.2 0.0 5.9e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RuvB_N PF05496.12 GBG84633.1 - 1.1e-05 25.2 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain gag-asp_proteas PF13975.6 GBG84633.1 - 1.5e-05 25.5 0.0 4.7e-05 23.9 0.0 1.9 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease AAA_16 PF13191.6 GBG84633.1 - 4e-05 24.1 0.0 0.00039 20.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GBG84633.1 - 7.8e-05 22.7 0.0 0.00039 20.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GBG84633.1 - 0.00077 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 GBG84633.1 - 0.00087 18.5 0.0 0.0028 16.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RVP_2 PF08284.11 GBG84633.1 - 0.00089 19.0 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease IstB_IS21 PF01695.17 GBG84633.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Retrotrans_gag PF03732.17 GBG84633.1 - 0.0019 18.4 0.3 0.01 16.1 0.1 2.4 2 0 0 2 2 1 1 Retrotransposon gag protein AAA_22 PF13401.6 GBG84633.1 - 0.0029 17.9 0.1 0.034 14.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GBG84633.1 - 0.0037 17.3 0.0 0.0094 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 GBG84633.1 - 0.0041 16.4 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RT_RNaseH PF17917.1 GBG84633.1 - 0.0062 16.8 0.0 0.019 15.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AAA_33 PF13671.6 GBG84633.1 - 0.011 15.9 0.0 0.038 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG84633.1 - 0.015 15.8 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GBG84633.1 - 0.024 14.2 0.1 4.3 6.9 0.1 2.4 1 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GBG84633.1 - 0.036 14.5 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GBG84633.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Asp_protease PF09668.10 GBG84633.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Mg_chelatase PF01078.21 GBG84633.1 - 0.11 11.9 0.2 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Senescence_reg PF04520.13 GBG84633.1 - 0.12 13.2 3.7 0.6 10.9 3.4 2.2 2 0 0 2 2 2 0 Senescence regulator AAA_17 PF13207.6 GBG84633.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 GBG84634.1 - 1.2e-19 70.1 0.0 2.3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 GBG84634.1 - 1.2e-06 28.3 0.6 3.9e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 AAA+ lid domain Chromo PF00385.24 GBG84634.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2201_N PF13203.6 GBG84635.1 - 0.19 11.3 4.3 0.23 11.0 4.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3381 PF11861.8 GBG84635.1 - 2.1 8.1 11.7 3.4 7.5 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4746 PF15928.5 GBG84635.1 - 3.3 7.0 9.3 4.4 6.6 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Vma12 PF11712.8 GBG84636.1 - 0.69 10.0 2.6 0.46 10.5 0.1 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4519 PF15012.6 GBG84636.1 - 8.7 6.6 7.6 31 4.8 7.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Peptidase_M8 PF01457.16 GBG84637.1 - 1.2e-26 93.6 0.1 1.7e-25 89.8 0.1 2.1 1 1 0 1 1 1 1 Leishmanolysin REV PF00424.18 GBG84640.1 - 0.1 12.6 3.1 0.18 11.9 0.2 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) LAP1C PF05609.12 GBG84640.1 - 0.23 10.5 15.9 0.29 10.2 15.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SH3-WW_linker PF16618.5 GBG84640.1 - 6.4 7.2 8.6 3.1 8.2 6.1 1.7 1 1 1 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 PG_binding_1 PF01471.18 GBG84642.1 - 3e-20 72.2 0.1 1.6e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Putative peptidoglycan binding domain NLPC_P60 PF00877.19 GBG84642.1 - 0.015 15.3 0.0 0.052 13.6 0.0 1.9 2 0 0 2 2 2 0 NlpC/P60 family Toprim_C_rpt PF13368.6 GBG84642.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat SURF2 PF05477.11 GBG84643.1 - 0.086 12.5 7.0 0.12 12.0 7.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SDA1 PF05285.12 GBG84643.1 - 0.28 10.5 25.5 0.36 10.2 25.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG84643.1 - 0.41 8.8 24.5 0.51 8.5 24.5 1.1 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 GBG84643.1 - 3.6 6.6 10.6 4.3 6.3 10.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 GBG84643.1 - 3.8 6.8 24.8 4.7 6.4 24.8 1.1 1 0 0 1 1 1 0 BUD22 Afi1 PF07792.12 GBG84643.1 - 4 7.9 11.4 21 5.6 11.4 2.0 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 GBG84643.1 - 4.3 5.5 19.4 5.9 5.0 19.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG84645.1 - 1.3e-12 47.7 0.1 2.2e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_1 PF00515.28 GBG84645.1 - 1.7e-05 24.4 0.1 0.19 11.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG84645.1 - 0.04 14.0 0.1 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG84645.1 - 0.19 12.0 0.3 43 4.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG84647.1 - 2.2e-29 102.6 0.0 3e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SRP19 PF01922.17 GBG84648.1 - 2e-28 99.1 0.1 2.6e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 SRP19 protein CDC45 PF02724.14 GBG84649.1 - 0.15 10.4 7.9 0.15 10.3 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG84649.1 - 0.2 11.1 11.7 0.24 10.8 11.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG84649.1 - 0.31 9.2 11.0 0.31 9.2 11.0 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG84649.1 - 0.47 10.1 10.0 0.59 9.8 10.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PTPRCAP PF15713.5 GBG84649.1 - 2.3 8.5 16.3 0.22 11.8 11.4 1.7 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated AAA PF00004.29 GBG84651.1 - 5.6e-40 136.8 0.0 9.3e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG84651.1 - 1.8e-10 40.5 0.0 4.3e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GBG84651.1 - 1.6e-07 31.4 0.0 6.5e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG84651.1 - 4e-07 29.9 0.0 1.3e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 GBG84651.1 - 2e-06 27.7 0.0 4.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 GBG84651.1 - 1.1e-05 25.6 0.0 1.8e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 GBG84651.1 - 3.5e-05 23.2 0.0 7.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 GBG84651.1 - 6e-05 23.5 0.5 0.0045 17.4 0.5 3.1 1 1 0 1 1 1 1 AAA ATPase domain MIT PF04212.18 GBG84651.1 - 7.1e-05 22.8 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.6 GBG84651.1 - 9.7e-05 22.7 0.2 0.018 15.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 GBG84651.1 - 0.0002 21.0 0.3 0.0038 16.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GBG84651.1 - 0.0051 16.2 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GBG84651.1 - 0.0074 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 GBG84651.1 - 0.008 15.6 0.0 0.94 8.9 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 GBG84651.1 - 0.015 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GBG84651.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GBG84651.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG84651.1 - 0.037 14.0 0.1 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 GBG84651.1 - 0.04 14.1 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GBG84651.1 - 0.052 13.9 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 GBG84651.1 - 0.052 12.7 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 GBG84651.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Flu_M1_C PF08289.11 GBG84651.1 - 0.13 12.4 0.1 0.34 11.2 0.1 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain AAA_17 PF13207.6 GBG84651.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 GBG84651.1 - 0.15 11.9 0.0 0.5 10.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 GBG84651.1 - 0.18 11.3 0.0 0.89 9.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region ZZ PF00569.17 GBG84652.1 - 4.8e-10 39.1 2.8 4.8e-10 39.1 2.8 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.6 GBG84652.1 - 2.1e-09 37.0 28.5 2.5e-06 27.2 9.1 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG84652.1 - 7.6e-09 35.3 22.8 2.4e-05 24.1 8.1 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG84652.1 - 1.3e-08 34.8 27.3 0.00013 22.0 8.7 3.1 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GBG84652.1 - 1.9e-07 31.0 19.8 0.00012 22.1 3.0 2.9 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GBG84652.1 - 2.9e-07 30.2 19.6 1e-06 28.5 6.0 3.5 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG84652.1 - 9.8e-07 28.5 27.2 7.9e-06 25.6 8.1 3.2 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GBG84652.1 - 8.2e-06 25.7 31.0 0.00023 21.0 5.8 3.5 4 0 0 4 4 4 2 zinc-RING finger domain zf-RING_4 PF14570.6 GBG84652.1 - 0.00042 20.1 1.4 0.00042 20.1 1.4 3.9 3 2 1 4 4 4 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 GBG84652.1 - 0.00077 19.7 8.5 0.00077 19.7 8.5 3.1 3 0 0 3 3 2 2 Ring finger domain zf-RING_6 PF14835.6 GBG84652.1 - 0.011 15.5 18.1 0.24 11.3 4.6 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GBG84652.1 - 0.019 15.2 5.2 0.019 15.2 5.2 3.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 GBG84652.1 - 0.79 9.9 24.6 0.99 9.6 8.3 2.9 3 0 0 3 3 2 0 zinc RING finger of MSL2 PRIMA1 PF16101.5 GBG84652.1 - 2.6 8.1 7.8 7.1 6.7 7.8 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RhoGAP PF00620.27 GBG84654.1 - 2.2e-21 76.2 2.8 6.5e-13 48.8 0.6 2.9 3 0 0 3 3 3 2 RhoGAP domain RVT_1 PF00078.27 GBG84654.1 - 1.2e-20 74.0 0.1 2.2e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lzipper-MIP1 PF14389.6 GBG84654.1 - 2.2e-09 37.5 2.8 2.2e-09 37.5 2.8 4.7 4 2 1 5 5 3 1 Leucine-zipper of ternary complex factor MIP1 rve PF00665.26 GBG84654.1 - 4e-06 27.0 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG84654.1 - 5.4e-05 23.7 0.0 0.00013 22.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84654.1 - 0.00016 22.2 0.0 0.00045 20.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84654.1 - 0.00017 21.4 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84654.1 - 0.026 14.3 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease PH PF00169.29 GBG84654.1 - 0.061 13.8 0.0 0.4 11.2 0.0 2.3 2 0 0 2 2 2 0 PH domain YlbD_coat PF14071.6 GBG84654.1 - 0.42 10.9 4.9 16 5.8 0.7 3.8 4 0 0 4 4 4 0 Putative coat protein DUF1664 PF07889.12 GBG84654.1 - 1.2 9.2 6.2 2 8.5 2.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) RhoGAP PF00620.27 GBG84655.1 - 2e-21 76.4 3.0 6e-13 48.9 0.6 3.0 3 0 0 3 3 3 2 RhoGAP domain RVT_1 PF00078.27 GBG84655.1 - 1.1e-20 74.1 0.1 2.1e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lzipper-MIP1 PF14389.6 GBG84655.1 - 2.1e-09 37.6 2.8 2.1e-09 37.6 2.8 4.8 4 2 1 5 5 5 1 Leucine-zipper of ternary complex factor MIP1 rve PF00665.26 GBG84655.1 - 3.7e-06 27.1 0.0 1e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG84655.1 - 5e-05 23.9 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84655.1 - 0.00014 22.4 0.0 0.00041 20.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84655.1 - 0.00016 21.5 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84655.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease PH PF00169.29 GBG84655.1 - 0.052 14.1 0.0 0.37 11.3 0.0 2.4 2 0 0 2 2 2 0 PH domain DUF1664 PF07889.12 GBG84655.1 - 0.75 9.8 5.9 2.3 8.3 3.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Drc1-Sld2 PF11719.8 GBG84656.1 - 1.6e-05 24.6 33.7 1.9e-05 24.4 33.7 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein CDC45 PF02724.14 GBG84656.1 - 6.6e-05 21.4 32.1 9.2e-05 20.9 32.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG84656.1 - 0.00016 20.1 25.6 0.00017 20.0 25.6 1.2 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 GBG84656.1 - 0.00036 20.7 42.7 0.00053 20.2 42.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein TFIIF_alpha PF05793.12 GBG84656.1 - 0.00066 18.4 36.6 0.00093 17.9 36.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Merozoite_SPAM PF07133.11 GBG84656.1 - 0.0028 17.7 42.3 0.0035 17.4 42.3 1.1 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) Sporozoite_P67 PF05642.11 GBG84656.1 - 0.055 11.6 8.1 0.059 11.5 8.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RR_TM4-6 PF06459.12 GBG84656.1 - 0.15 11.9 28.4 0.19 11.5 28.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Arabino_trans_C PF14896.6 GBG84656.1 - 0.22 10.5 7.2 0.29 10.1 7.2 1.1 1 0 0 1 1 1 0 EmbC C-terminal domain LTV PF04180.14 GBG84656.1 - 0.39 10.4 26.5 0.52 10.0 26.5 1.1 1 0 0 1 1 1 0 Low temperature viability protein CCSAP PF15748.5 GBG84656.1 - 0.52 10.4 32.2 0.86 9.7 32.2 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Zip PF02535.22 GBG84656.1 - 0.56 9.4 10.2 0.59 9.3 10.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.17 GBG84656.1 - 0.67 10.1 10.4 1 9.5 10.4 1.4 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 GBG84656.1 - 0.91 8.2 19.4 1.1 7.9 19.4 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 GBG84656.1 - 0.94 8.3 16.4 1.1 8.1 16.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLC12 PF03522.15 GBG84656.1 - 1.2 8.0 19.5 1.5 7.7 19.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Otopetrin PF03189.13 GBG84656.1 - 2.1 7.1 3.1 2.2 7.0 3.1 1.3 1 0 0 1 1 1 0 Otopetrin Raftlin PF15250.6 GBG84656.1 - 2.6 6.7 16.2 3.2 6.4 16.2 1.2 1 0 0 1 1 1 0 Raftlin LicD PF04991.13 GBG84656.1 - 2.7 8.1 11.3 3.6 7.7 11.3 1.3 1 0 0 1 1 1 0 LicD family LAP1C PF05609.12 GBG84656.1 - 2.8 6.9 17.6 3.5 6.6 17.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SRP-alpha_N PF04086.13 GBG84656.1 - 3.9 7.3 30.9 5.9 6.7 30.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ALMT PF11744.8 GBG84656.1 - 5.9 5.6 14.1 7.9 5.2 14.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4569 PF15133.6 GBG84656.1 - 7.8 6.1 15.1 9.3 5.9 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF913 PF06025.12 GBG84656.1 - 9.2 5.1 13.9 12 4.8 13.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) zf-CCHC PF00098.23 GBG84658.1 - 1.7e-07 31.0 2.9 3.6e-07 30.0 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG84658.1 - 0.07 13.1 1.3 0.15 12.1 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG84658.1 - 0.095 12.5 4.5 0.083 12.7 0.9 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG84658.1 - 0.14 11.9 0.9 0.33 10.7 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG84658.1 - 0.23 11.2 1.6 0.51 10.1 1.6 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF1104 PF06518.11 GBG84658.1 - 0.58 10.6 6.6 1.4 9.3 6.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DUF659 PF04937.15 GBG84659.1 - 3e-16 59.7 0.0 7.8e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) BUD22 PF09073.10 GBG84660.1 - 0.19 11.1 15.4 0.24 10.7 15.4 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG84660.1 - 0.78 7.9 14.5 0.97 7.6 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG84660.1 - 0.89 8.9 13.4 1.1 8.6 13.4 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG84660.1 - 1.6 8.4 12.9 2 8.1 12.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG84660.1 - 6.8 4.9 11.5 8.3 4.6 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Urb2 PF10441.9 GBG84661.1 - 8e-19 68.4 0.0 2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Urb2/Npa2 family Toxin_12 PF07740.12 GBG84661.1 - 0.55 11.0 3.1 2.2 9.1 3.1 2.0 1 0 0 1 1 1 0 Ion channel inhibitory toxin FAD_binding_6 PF00970.24 GBG84662.1 - 1.8e-29 102.0 0.0 4.3e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain RT_RNaseH PF17917.1 GBG84662.1 - 3.6e-19 69.0 0.7 8e-19 67.9 0.7 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84662.1 - 8.6e-12 45.3 0.1 8.6e-12 45.3 0.1 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG84662.1 - 3.1e-11 43.2 0.1 9e-11 41.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RRM_1 PF00076.22 GBG84663.1 - 1.3e-40 137.0 0.0 2e-19 69.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG84663.1 - 7.3e-05 22.8 0.1 0.0042 17.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 GBG84663.1 - 0.0028 17.3 0.1 1.4 8.7 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_5 PF13893.6 GBG84663.1 - 0.075 12.6 0.0 0.21 11.2 0.0 1.6 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GBG84663.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 CBFB_NFYA PF02045.15 GBG84664.1 - 4e-10 40.2 0.9 7e-10 39.4 0.9 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B CBFB_NFYA PF02045.15 GBG84665.1 - 3.1e-10 40.5 0.9 5.4e-10 39.8 0.9 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Mod_r PF07200.13 GBG84666.1 - 0.018 15.2 5.4 0.018 15.2 5.4 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Sec8_exocyst PF04048.14 GBG84666.1 - 0.018 14.9 0.3 0.018 14.9 0.3 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain BORCS7 PF16088.5 GBG84666.1 - 0.021 15.1 0.6 0.044 14.1 0.6 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 RabGAP-TBC PF00566.18 GBG84666.1 - 0.022 14.4 0.4 0.022 14.4 0.4 1.7 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Hus1 PF04005.12 GBG84666.1 - 0.13 11.3 3.1 0.38 9.8 1.6 2.0 2 0 0 2 2 2 0 Hus1-like protein DASH_Dam1 PF08653.10 GBG84666.1 - 0.15 11.9 0.5 2.9 7.8 0.1 2.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 Rootletin PF15035.6 GBG84666.1 - 1 9.4 24.1 17 5.4 24.1 2.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RPW8 PF05659.11 GBG84666.1 - 1.2 8.8 9.0 0.47 10.1 4.8 2.2 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1664 PF07889.12 GBG84666.1 - 1.4 9.0 7.2 0.15 12.1 2.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 GBG84666.1 - 4.6 7.9 14.2 0.069 13.8 4.6 2.7 3 1 0 3 3 3 0 Initiation control protein YabA CBFB_NFYA PF02045.15 GBG84668.1 - 2e-26 92.4 2.7 2e-26 92.4 2.7 2.4 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Presenilin PF01080.17 GBG84668.1 - 0.98 8.1 6.5 1.3 7.8 6.5 1.1 1 0 0 1 1 1 0 Presenilin Codanin-1_C PF15296.6 GBG84668.1 - 1.5 8.9 6.6 3.4 7.8 6.6 1.6 1 1 0 1 1 1 0 Codanin-1 C-terminus DUF4407 PF14362.6 GBG84668.1 - 5.2 6.3 10.1 8.6 5.6 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SDA1 PF05285.12 GBG84669.1 - 0.88 8.9 26.8 1.1 8.6 26.8 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 GBG84669.1 - 2.2 8.3 29.3 3.3 7.8 29.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GBG84669.1 - 3.7 7.2 24.0 6 6.5 24.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG84669.1 - 4.2 5.5 20.6 5.8 5.1 20.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG84669.1 - 4.4 5.4 26.8 5.8 5.0 26.8 1.1 1 0 0 1 1 1 0 Nop14-like family Fasciclin PF02469.22 GBG84670.1 - 1.5e-07 31.7 0.0 2.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Castor_Poll_mid PF06241.12 GBG84671.1 - 2e-20 72.7 0.0 8.5e-20 70.7 0.0 2.0 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 GBG84671.1 - 3.4e-05 23.6 0.0 0.002 17.9 0.0 2.6 2 0 0 2 2 2 1 TrkA-C domain DUF2637 PF10935.8 GBG84671.1 - 0.07 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) Integrase_H2C2 PF17921.1 GBG84672.1 - 1.8e-14 53.5 0.5 5e-14 52.1 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG84672.1 - 9.2e-14 51.7 0.0 2.4e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG84672.1 - 0.066 13.4 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger PPR_2 PF13041.6 GBG84673.1 - 7.1e-66 218.2 7.3 1.2e-10 41.4 0.0 11.9 3 3 10 13 13 13 11 PPR repeat family PPR PF01535.20 GBG84673.1 - 4.7e-60 195.8 22.1 5.5e-08 32.5 0.1 13.7 13 1 0 13 13 13 11 PPR repeat PPR_1 PF12854.7 GBG84673.1 - 1.1e-53 178.5 0.0 1.2e-07 31.3 0.0 12.2 12 0 0 12 12 12 9 PPR repeat PPR_3 PF13812.6 GBG84673.1 - 1.8e-53 178.5 0.0 4.8e-11 42.6 0.0 8.6 4 3 6 10 10 10 9 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG84673.1 - 1e-30 106.7 0.0 1.6e-07 30.9 0.0 5.5 1 1 4 5 5 5 5 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG84673.1 - 1.1e-08 35.5 0.0 0.58 10.7 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG84673.1 - 9.4e-08 32.3 10.5 0.98 10.4 0.0 8.5 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG84673.1 - 1.8e-07 30.7 1.0 1 9.6 0.0 7.4 9 0 0 9 9 8 1 Tetratricopeptide repeat COX5A PF02284.16 GBG84673.1 - 0.00099 19.1 0.0 2.1 8.4 0.0 3.6 3 1 1 4 4 4 1 Cytochrome c oxidase subunit Va PYRIN PF02758.16 GBG84673.1 - 0.0061 16.7 0.3 7.4 6.8 0.0 4.1 5 0 0 5 5 4 1 PAAD/DAPIN/Pyrin domain TPR_15 PF13429.6 GBG84673.1 - 0.015 14.5 0.1 1.4 8.1 0.0 3.5 3 1 2 5 5 5 0 Tetratricopeptide repeat Thi4 PF01946.17 GBG84673.1 - 0.016 14.5 0.2 0.18 11.1 0.0 2.3 1 1 1 2 2 2 0 Thi4 family TPR_10 PF13374.6 GBG84673.1 - 0.02 14.8 0.4 21 5.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3874 PF12990.7 GBG84673.1 - 0.065 13.6 0.5 0.79 10.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknonw function from B. Theta Gene description (DUF3874) TPR_2 PF07719.17 GBG84673.1 - 0.075 13.2 4.3 7.6 6.9 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG84673.1 - 0.12 12.6 0.1 39 4.6 0.1 4.5 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 RFXA_RFXANK_bdg PF15289.6 GBG84674.1 - 1.6 9.1 5.2 1.2 9.5 3.0 1.9 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Histone PF00125.24 GBG84675.1 - 5.4e-16 59.2 0.0 5.4e-16 59.2 0.0 2.3 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG84675.1 - 0.11 12.9 0.2 0.28 11.6 0.2 1.6 1 0 0 1 1 1 0 CENP-S protein zf-U11-48K PF05253.12 GBG84675.1 - 0.18 11.7 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger RT_RNaseH_2 PF17919.1 GBG84676.1 - 4.2e-29 100.5 0.0 1.1e-28 99.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84676.1 - 1.3e-27 96.1 0.0 3.7e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84676.1 - 7.7e-19 67.6 0.5 1.9e-18 66.3 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG84676.1 - 0.0012 19.1 0.1 0.0028 17.9 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG84676.1 - 0.04 13.5 0.0 0.04 13.5 0.0 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG84676.1 - 0.041 13.4 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2870 PF11069.8 GBG84676.1 - 0.081 13.3 4.1 0.22 11.9 4.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DnaJ PF00226.31 GBG84677.1 - 1.1e-12 47.8 0.4 3.8e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain zf-CCHC PF00098.23 GBG84678.1 - 0.0029 17.6 1.3 0.0054 16.8 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG84678.1 - 0.0053 17.0 0.1 0.32 11.3 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein RecG_N PF17190.4 GBG84680.1 - 0.04 14.6 1.9 0.078 13.7 0.4 2.2 2 0 0 2 2 2 0 RecG N-terminal helical domain PUF PF00806.19 GBG84682.1 - 6.2e-63 205.1 3.5 2.4e-12 45.8 0.1 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf_CCCH_4 PF18345.1 GBG84682.1 - 7.1e-06 25.9 4.6 1.5e-05 24.9 4.6 1.6 1 0 0 1 1 1 1 Zinc finger domain TFIIA PF03153.13 GBG84682.1 - 9.2e-06 25.9 66.7 0.0081 16.2 36.8 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit zf-CCCH PF00642.24 GBG84682.1 - 1e-05 25.3 2.9 2.1e-05 24.3 2.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GBG84682.1 - 0.0078 16.7 1.2 0.016 15.7 1.2 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 GBG84682.1 - 0.0093 15.8 3.3 0.025 14.4 3.3 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger Dapper PF15268.6 GBG84682.1 - 0.014 14.3 30.9 0.029 13.3 14.8 2.1 2 0 0 2 2 2 0 Dapper DDHD PF02862.17 GBG84682.1 - 0.044 13.9 20.0 0.012 15.8 9.1 2.3 2 0 0 2 2 2 0 DDHD domain CNDH2_C PF16858.5 GBG84682.1 - 0.089 12.7 26.1 0.2 11.5 14.0 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BAF1_ABF1 PF04684.13 GBG84682.1 - 1.5 7.8 24.7 0.3 10.1 11.9 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF4011 PF13195.6 GBG84682.1 - 3.2 7.6 12.5 3.7 7.4 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) SPX PF03105.19 GBG84682.1 - 3.9 7.3 24.5 8.5 6.2 0.7 2.2 2 0 0 2 2 2 0 SPX domain RT_RNaseH_2 PF17919.1 GBG84683.1 - 3.4e-26 91.2 0.0 9.6e-26 89.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84683.1 - 3.6e-25 88.3 0.0 9.5e-25 86.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84683.1 - 4.2e-24 85.3 0.0 9.6e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84683.1 - 2.5e-07 31.3 0.0 7e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG84683.1 - 5.6e-07 29.6 0.1 1.8e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG84683.1 - 1.2e-06 28.6 2.1 0.00061 20.0 0.1 3.6 3 0 0 3 3 3 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG84683.1 - 1.6e-06 27.9 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG84683.1 - 3.4e-05 24.3 0.0 8.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG84683.1 - 0.00034 20.4 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG84685.1 - 6.4e-18 64.6 0.0 1.4e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84685.1 - 9.3e-09 35.1 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84685.1 - 3.4e-07 30.5 0.0 7.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG84685.1 - 0.48 8.6 39.0 0.74 7.9 39.0 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG84685.1 - 1.4 8.1 33.8 2.1 7.6 33.8 1.2 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 GBG84685.1 - 1.5 8.4 25.5 2.5 7.6 25.5 1.4 1 0 0 1 1 1 0 PPP4R2 Lin-8 PF03353.15 GBG84685.1 - 2.2 7.7 19.7 3.8 7.0 19.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LAP1C PF05609.12 GBG84685.1 - 7.8 5.5 20.8 12 4.8 20.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Vfa1 PF08432.10 GBG84685.1 - 8.4 6.7 21.2 14 6.0 21.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 VIR_N PF15912.5 GBG84685.1 - 8.9 5.8 18.4 19 4.7 18.4 1.7 1 0 0 1 1 1 0 Virilizer, N-terminal adh_short PF00106.25 GBG84686.1 - 2.9e-30 105.2 0.8 7.6e-15 54.9 0.0 3.8 3 1 1 4 4 4 3 short chain dehydrogenase adh_short_C2 PF13561.6 GBG84686.1 - 5.7e-24 85.0 5.8 1e-10 41.6 0.0 4.0 3 1 1 4 4 4 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG84686.1 - 0.0029 17.6 0.2 0.031 14.2 0.3 2.1 2 0 0 2 2 2 1 KR domain TFB6 PF17110.5 GBG84686.1 - 0.59 9.9 3.0 2 8.1 0.6 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Pex24p PF06398.11 GBG84687.1 - 0.012 14.6 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Wzy_C PF04932.15 GBG84687.1 - 0.035 13.7 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase Lig_chan PF00060.26 GBG84687.1 - 0.095 12.5 0.0 0.099 12.5 0.0 1.1 1 0 0 1 1 1 0 Ligand-gated ion channel SDA1 PF05285.12 GBG84687.1 - 7 6.0 40.8 9.9 5.5 40.8 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG84687.1 - 8.8 5.0 9.4 9.7 4.8 9.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Phe_ZIP PF08916.11 GBG84688.1 - 0.27 12.0 4.9 1.9 9.2 0.0 3.5 4 0 0 4 4 4 0 Phenylalanine zipper Cys_rich_FGFR PF00839.17 GBG84688.1 - 1.3 9.3 8.1 1.6 8.9 1.7 2.7 3 0 0 3 3 3 0 Cysteine rich repeat Retrotrans_gag PF03732.17 GBG84689.1 - 0.0012 19.0 0.2 0.0012 19.0 0.2 2.2 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG84689.1 - 0.015 15.0 0.7 0.043 13.6 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) SoPB_HTH PF18090.1 GBG84689.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Centromere-binding protein HTH domain DDE_Tnp_4 PF13359.6 GBG84690.1 - 5.6e-15 55.3 0.0 6.5e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84690.1 - 3.5e-05 23.5 0.0 4.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein zf-CCHC PF00098.23 GBG84691.1 - 0.027 14.5 2.6 0.057 13.5 2.6 1.6 1 0 0 1 1 1 0 Zinc knuckle SmAKAP PF15127.6 GBG84691.1 - 2.7 9.2 9.9 13 7.1 9.9 2.1 1 0 0 1 1 1 0 Small membrane A-kinase anchor protein ArAE_2_N PF10337.9 GBG84691.1 - 3.5 6.6 7.8 0.81 8.6 4.6 1.4 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Borrelia_P83 PF05262.11 GBG84691.1 - 5.3 5.4 20.4 6.3 5.2 20.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ALMT PF11744.8 GBG84691.1 - 6.7 5.4 8.8 12 4.5 8.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2052 PF09747.9 GBG84691.1 - 9.5 6.3 19.2 1.8 8.7 13.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 GBG84692.1 - 7.4 5.2 8.5 9.7 4.8 8.5 1.3 1 0 0 1 1 1 0 Presenilin DDE_Tnp_4 PF13359.6 GBG84693.1 - 3.1e-26 91.9 0.0 1.5e-25 89.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84693.1 - 3.7e-12 46.3 0.0 5.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84693.1 - 3e-05 23.8 0.0 0.076 12.6 0.0 3.1 3 0 0 3 3 3 2 Transposase DDE domain IlvB_leader PF08049.11 GBG84693.1 - 0.15 12.0 5.0 0.36 10.8 5.0 1.6 1 0 0 1 1 1 0 IlvB leader peptide DDE_Tnp_4 PF13359.6 GBG84694.1 - 3.1e-25 88.7 0.0 6.1e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84694.1 - 3.3e-10 39.9 0.0 5.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DHO_dh PF01180.21 GBG84695.1 - 1.5e-33 116.3 0.0 1.9e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 GBG84695.1 - 0.018 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Phage_lysozyme PF00959.19 GBG84697.1 - 0.016 15.6 0.6 0.74 10.3 0.0 3.5 2 0 0 2 2 2 0 Phage lysozyme zf-CCHC_4 PF14392.6 GBG84697.1 - 0.084 12.6 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG84697.1 - 0.18 12.0 0.5 0.35 11.0 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_1 PF00561.20 GBG84698.1 - 4.5e-21 75.7 0.8 1.1e-19 71.2 0.1 2.6 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG84698.1 - 7.1e-14 51.6 0.1 3.2e-13 49.5 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG84698.1 - 3e-10 41.1 0.0 4.6e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 GBG84698.1 - 3.5e-05 24.0 0.2 0.0049 17.0 0.1 2.6 2 1 0 2 2 2 1 Thioesterase domain Ndr PF03096.14 GBG84698.1 - 0.012 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family Esterase PF00756.20 GBG84698.1 - 0.018 14.7 1.6 0.084 12.5 1.6 2.0 1 1 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 GBG84698.1 - 0.055 13.2 0.9 0.24 11.1 0.7 2.0 1 1 1 2 2 2 0 PGAP1-like protein Auxin_inducible PF02519.14 GBG84699.1 - 0.00057 20.0 0.1 0.0015 18.6 0.1 1.7 1 1 0 1 1 1 1 Auxin responsive protein BTB_2 PF02214.22 GBG84699.1 - 0.004 17.5 0.1 0.0085 16.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain DZR PF12773.7 GBG84699.1 - 0.038 14.0 3.8 0.23 11.5 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon DUF659 PF04937.15 GBG84701.1 - 1.3e-16 60.8 0.0 2.6e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG84701.1 - 7.4e-06 25.7 0.1 2.1e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4471 PF14740.6 GBG84701.1 - 0.00062 19.1 0.6 0.0011 18.3 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) RNA_pol_3_Rpc31 PF11705.8 GBG84701.1 - 0.01 16.1 18.1 0.01 16.1 18.1 3.5 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 SpoIIP PF07454.11 GBG84701.1 - 0.4 10.1 5.3 0.87 9.0 5.3 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Paf1 PF03985.13 GBG84701.1 - 4.3 6.2 23.2 10 5.0 23.2 1.5 1 0 0 1 1 1 0 Paf1 DUF3464 PF11947.8 GBG84701.1 - 6.2 6.6 7.3 24 4.7 7.3 2.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RPA43_OB PF17875.1 GBG84701.1 - 9.8 6.8 7.8 41 4.8 7.8 2.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DOMON PF03351.17 GBG84702.1 - 3.5e-18 66.0 9.6 2.2e-07 31.1 0.3 3.4 2 1 1 3 3 3 3 DOMON domain Cytochrom_B561 PF03188.16 GBG84702.1 - 3.5e-08 33.7 3.9 9.6e-08 32.3 3.9 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 GBG84702.1 - 0.00017 21.4 0.7 0.00017 21.4 0.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) CD20 PF04103.15 GBG84702.1 - 0.037 14.1 0.1 0.037 14.1 0.1 1.9 2 0 0 2 2 2 0 CD20-like family Paramyxo_P_V_N PF13825.6 GBG84702.1 - 2.2 7.7 4.6 3.9 6.8 4.6 1.3 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus DDE_Tnp_4 PF13359.6 GBG84703.1 - 2e-14 53.5 0.0 1e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Asp_protease_2 PF13650.6 GBG84703.1 - 6e-07 30.0 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84703.1 - 7.2e-07 29.7 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84703.1 - 7.5e-07 29.0 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84703.1 - 5.4e-05 23.0 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Plant_tran PF04827.14 GBG84703.1 - 8.4e-05 22.3 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein RVT_1 PF00078.27 GBG84703.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M16 PF00675.20 GBG84704.1 - 3.1e-41 140.8 0.0 6.6e-41 139.8 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GBG84704.1 - 2.1e-36 125.6 0.0 3.3e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Tet_JBP PF12851.7 GBG84705.1 - 0.038 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Claudin_2 PF13903.6 GBG84706.1 - 0.14 11.9 0.0 16 5.1 0.0 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SDA1 PF05285.12 GBG84706.1 - 0.43 9.9 12.7 0.59 9.5 12.7 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG84706.1 - 0.88 7.7 14.4 1.1 7.4 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG84706.1 - 2 6.6 10.2 2.7 6.2 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG84706.1 - 4.9 5.1 19.5 6.7 4.7 19.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Aldo_ket_red PF00248.21 GBG84707.1 - 6e-41 140.5 0.0 5.4e-33 114.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family K_channel_TID PF07941.11 GBG84709.1 - 0.42 11.1 12.8 0.12 12.9 8.4 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain KAR9 PF08580.10 GBG84710.1 - 0.13 10.8 0.3 0.16 10.5 0.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SdiA-regulated PF06977.11 GBG84711.1 - 0.057 12.6 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 SdiA-regulated DEK_C PF08766.11 GBG84712.1 - 0.0026 17.7 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain PilN PF05137.13 GBG84712.1 - 0.078 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) Pkinase_Tyr PF07714.17 GBG84713.1 - 2.3e-29 102.5 2.5 2.8e-29 102.2 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG84713.1 - 7.6e-29 100.9 0.0 7.6e-29 100.9 0.0 3.2 4 0 0 4 4 4 1 Protein kinase domain APH PF01636.23 GBG84713.1 - 0.0004 20.4 0.1 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG84713.1 - 0.016 14.0 0.1 0.016 14.0 0.1 2.3 2 0 0 2 2 2 0 Fungal protein kinase DUF2755 PF10954.8 GBG84713.1 - 0.04 13.8 0.1 0.097 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) NHL PF01436.21 GBG84713.1 - 0.089 12.9 0.3 13 6.0 0.0 3.4 3 0 0 3 3 3 0 NHL repeat DUF3138 PF11336.8 GBG84713.1 - 0.13 10.8 1.8 0.25 9.9 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TssO PF17561.2 GBG84713.1 - 0.65 10.1 5.9 1.5 9.0 5.9 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO Pkinase PF00069.25 GBG84714.1 - 7e-33 114.1 0.0 1.4e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84714.1 - 2.4e-31 109.0 0.0 2.4e-30 105.7 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG84714.1 - 1.5e-07 31.6 0.3 7.7e-06 26.0 0.3 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family SGL PF08450.12 GBG84714.1 - 0.00083 19.0 0.0 0.015 14.9 0.0 2.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 GBG84714.1 - 0.0029 16.9 0.0 0.028 13.7 0.0 2.2 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Pkinase_fungal PF17667.1 GBG84714.1 - 0.0079 15.0 0.6 0.015 14.1 0.6 1.5 1 1 0 1 1 1 1 Fungal protein kinase Phyto-Amp PF15438.6 GBG84715.1 - 0.01 15.7 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma OmpH PF03938.14 GBG84715.1 - 5.2 7.4 12.7 0.76 10.1 5.8 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DDE_Tnp_4 PF13359.6 GBG84716.1 - 1.9e-22 79.7 0.0 4.1e-22 78.5 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84716.1 - 2.4e-10 40.4 0.0 3.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84716.1 - 0.018 14.7 0.1 0.097 12.3 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG84717.1 - 0.00044 20.6 2.3 0.00044 20.6 2.3 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG84717.1 - 0.14 12.5 0.8 0.36 11.2 0.8 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like gag-asp_proteas PF13975.6 GBG84718.1 - 0.0016 19.0 0.1 0.0041 17.6 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84718.1 - 0.0039 17.8 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG84718.1 - 0.04 14.0 1.9 0.069 13.3 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG84718.1 - 0.08 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RT_RNaseH PF17917.1 GBG84720.1 - 8e-22 77.5 0.0 1.6e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84720.1 - 7.2e-20 70.9 0.0 1.3e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84720.1 - 3.1e-13 49.6 0.2 7.3e-13 48.4 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG84720.1 - 1.5e-05 24.6 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG84720.1 - 0.00088 19.5 0.0 0.0032 17.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Jnk-SapK_ap_N PF09744.9 GBG84720.1 - 0.0095 16.2 2.3 0.022 15.0 2.3 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 gag-asp_proteas PF13975.6 GBG84721.1 - 6.7e-05 23.4 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84721.1 - 0.0016 19.0 0.0 0.0053 17.4 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG84721.1 - 0.24 11.2 1.2 0.42 10.4 1.2 1.3 1 0 0 1 1 1 0 Aspartyl protease Nop14 PF04147.12 GBG84722.1 - 0.024 12.9 26.1 0.025 12.8 26.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG84722.1 - 0.15 10.4 15.4 0.16 10.2 15.4 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG84722.1 - 2.8 7.3 24.7 2.6 7.4 24.7 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG84722.1 - 2.9 7.2 18.5 2.6 7.3 18.5 1.1 1 0 0 1 1 1 0 BUD22 Connexin PF00029.19 GBG84722.1 - 5 6.8 4.8 4.8 6.9 4.8 1.1 1 0 0 1 1 1 0 Connexin Paf1 PF03985.13 GBG84722.1 - 5.7 5.8 23.8 5.8 5.8 23.8 1.1 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 GBG84722.1 - 6.8 5.9 21.0 9.8 5.4 21.0 1.4 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 GBG84722.1 - 8.7 5.0 7.6 8.7 5.0 7.6 1.0 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG84723.1 - 0.095 10.9 18.2 0.11 10.7 18.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG84723.1 - 0.31 10.4 15.5 0.36 10.2 15.5 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GBG84723.1 - 0.32 9.1 20.1 0.39 8.8 20.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi TbpB_B_D PF01298.18 GBG84723.1 - 0.6 10.5 5.4 0.87 10.0 3.8 2.0 1 1 1 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B CDC45 PF02724.14 GBG84723.1 - 0.85 7.8 12.8 1.1 7.5 12.8 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG84723.1 - 0.94 8.8 14.9 1.1 8.5 14.9 1.2 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 GBG84723.1 - 0.95 9.2 10.9 1.4 8.6 10.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RRN3 PF05327.11 GBG84723.1 - 3.4 6.1 11.3 4.2 5.8 11.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 GBG84723.1 - 6 5.5 5.4 6.7 5.4 5.4 1.1 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG84724.1 - 3e-28 98.9 0.1 5.2e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84724.1 - 1.4e-26 92.4 0.0 8.7e-26 89.9 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84724.1 - 2.5e-24 85.6 0.0 8.7e-24 83.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG84724.1 - 1.4e-07 32.0 0.0 2.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG84724.1 - 3.8e-07 30.1 0.1 8.8e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG84724.1 - 8.7e-07 29.4 0.0 1.8e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84724.1 - 8.3e-06 25.6 0.0 2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84724.1 - 0.0003 20.6 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG84725.1 - 5.1e-31 107.9 0.0 1e-30 107.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84725.1 - 3.1e-23 81.7 0.0 7.9e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84725.1 - 2.3e-19 69.6 0.0 5.8e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG84725.1 - 3.1e-07 31.0 0.0 8.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84725.1 - 1.1e-05 25.9 0.0 3.2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84725.1 - 9.2e-05 22.2 0.0 0.00025 20.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3450 PF11932.8 GBG84725.1 - 0.077 12.3 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ECH_1 PF00378.20 GBG84726.1 - 4.6e-21 75.3 0.0 6.7e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 GBG84726.1 - 1e-10 41.7 0.0 2.5e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain ECH_2 PF16113.5 GBG84726.1 - 0.014 14.9 0.1 0.035 13.6 0.1 1.6 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF659 PF04937.15 GBG84727.1 - 1.7e-16 60.5 0.0 2.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) XkdW PF09636.10 GBG84727.1 - 0.75 9.9 2.5 2 8.5 2.5 1.7 1 0 0 1 1 1 0 XkdW protein Formyl_trans_N PF00551.19 GBG84729.1 - 6.2e-12 45.6 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 GBG84729.1 - 6.8e-12 45.5 0.0 1.6e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain ECH_1 PF00378.20 GBG84729.1 - 6.5e-09 35.5 0.1 1e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GBG84730.1 - 3.5e-22 78.9 0.0 5.4e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 GBG84730.1 - 5.3e-12 45.9 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Formyl_trans_N PF00551.19 GBG84730.1 - 9e-12 45.1 0.0 1.7e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase ECH_2 PF16113.5 GBG84730.1 - 0.0046 16.5 0.1 0.0093 15.5 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chromo PF00385.24 GBG84731.1 - 2e-11 43.6 0.0 3.6e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG84731.1 - 1.6e-10 41.2 0.0 3.8e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG84733.1 - 0.0038 17.2 4.1 0.0081 16.2 4.1 1.6 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH PF17917.1 GBG84734.1 - 2.2e-15 56.8 0.0 5.5e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84734.1 - 7.4e-12 45.2 0.0 3.6e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG84734.1 - 1.7e-05 25.3 0.0 4.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84734.1 - 0.00028 21.5 0.0 0.00075 20.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG84734.1 - 0.05 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG84736.1 - 6.3e-19 67.8 0.5 1.2e-18 67.0 0.2 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG84736.1 - 5e-17 62.2 0.0 1e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG84736.1 - 0.011 15.5 0.0 0.091 12.6 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 GBG84736.1 - 0.026 14.7 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF1564 PF07600.11 GBG84736.1 - 0.14 11.8 0.0 0.5 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG84737.1 - 1e-31 110.2 0.0 1.9e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84737.1 - 4.1e-15 55.6 0.0 1.1e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84737.1 - 8.5e-15 54.6 0.6 2.9e-14 52.9 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG84737.1 - 1.1e-12 48.2 0.0 3.8e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG84737.1 - 6.5e-12 45.2 0.0 1.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG84737.1 - 0.00059 20.0 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG84737.1 - 0.002 18.4 0.0 0.0051 17.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84739.1 - 2.7e-19 69.0 0.6 6.9e-19 67.7 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF659 PF04937.15 GBG84739.1 - 4.1e-19 68.9 0.0 8.7e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG84739.1 - 2.7e-16 59.8 0.0 4.9e-14 52.6 0.0 2.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG84739.1 - 1.2e-13 51.0 0.0 2.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84739.1 - 2e-12 47.3 0.0 9.4e-12 45.2 0.0 2.2 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84739.1 - 2.9e-05 23.7 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG84739.1 - 0.013 15.8 0.2 0.033 14.4 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG84739.1 - 0.046 13.5 0.1 0.084 12.7 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG84739.1 - 0.082 12.6 0.3 0.23 11.1 0.3 1.8 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVP_2 PF08284.11 GBG84739.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG84739.1 - 0.17 12.1 2.3 0.4 10.8 2.3 1.7 1 0 0 1 1 1 0 Zinc knuckle PAN_4 PF14295.6 GBG84740.1 - 0.00019 21.3 6.0 0.00026 20.9 6.0 1.2 1 0 0 1 1 1 1 PAN domain QH-AmDH_gamma PF08992.11 GBG84740.1 - 0.0055 16.7 1.9 0.007 16.3 1.9 1.4 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase, gamma subunit gag-asp_proteas PF13975.6 GBG84741.1 - 6.2e-07 29.9 0.1 1.8e-06 28.4 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84741.1 - 1.7e-05 25.3 0.1 4.9e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG84741.1 - 0.0003 20.6 0.1 0.00061 19.6 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG84741.1 - 0.0093 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-RING_5 PF14634.6 GBG84742.1 - 3.2e-05 23.8 4.0 3.2e-05 23.8 4.0 6.9 7 2 1 8 8 8 1 zinc-RING finger domain zf-RING_2 PF13639.6 GBG84742.1 - 0.00016 21.9 4.6 0.00016 21.9 4.6 7.2 7 1 0 7 7 7 1 Ring finger domain Sgf11 PF08209.11 GBG84742.1 - 0.064 12.8 0.1 0.064 12.8 0.1 4.6 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) Rad50_zn_hook PF04423.14 GBG84742.1 - 0.38 10.6 7.4 6.3 6.7 0.1 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif Peptidase_C48 PF02902.19 GBG84743.1 - 1.6e-13 51.0 1.0 3e-13 50.1 0.6 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Integrase_H2C2 PF17921.1 GBG84744.1 - 4e-14 52.5 0.4 4e-14 52.5 0.4 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG84744.1 - 5.6e-12 45.9 0.0 1.3e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG84744.1 - 4.6e-09 36.7 0.2 1.4e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84744.1 - 2.8e-07 31.1 0.0 6.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG84744.1 - 0.00092 19.0 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG84744.1 - 0.0043 17.3 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1664 PF07889.12 GBG84744.1 - 0.018 15.0 2.6 0.12 12.4 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SseC PF04888.12 GBG84744.1 - 0.059 13.0 2.3 0.12 12.0 2.3 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family USP8_interact PF08941.10 GBG84744.1 - 0.17 11.7 4.3 0.38 10.6 4.3 1.5 1 0 0 1 1 1 0 USP8 interacting zf-RING_5 PF14634.6 GBG84745.1 - 2.9e-05 23.9 4.4 2.9e-05 23.9 4.4 7.3 7 3 2 9 9 9 1 zinc-RING finger domain zf-RING_2 PF13639.6 GBG84745.1 - 5.1e-05 23.5 4.9 5.1e-05 23.5 4.9 7.3 8 0 0 8 8 8 1 Ring finger domain Sgf11 PF08209.11 GBG84745.1 - 0.066 12.8 0.1 0.066 12.8 0.1 4.5 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) Rad50_zn_hook PF04423.14 GBG84745.1 - 0.38 10.6 8.0 3.7 7.4 0.1 3.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-CCHC PF00098.23 GBG84746.1 - 2.3e-06 27.4 4.0 4.5e-06 26.5 4.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG84746.1 - 0.0068 16.2 3.8 0.011 15.6 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle Ribosomal_S8 PF00410.19 GBG84746.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S8 TLP-20 PF06088.11 GBG84747.1 - 0.021 14.8 0.5 0.042 13.7 0.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) THDPS_N PF14790.6 GBG84747.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal SAPS PF04499.15 GBG84747.1 - 2 7.1 6.7 2.7 6.7 6.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_23 PF13476.6 GBG84747.1 - 2.8 8.4 9.9 4.4 7.7 9.9 1.2 1 0 0 1 1 1 0 AAA domain Nop14 PF04147.12 GBG84747.1 - 3 5.9 27.4 4.2 5.5 27.4 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 GBG84747.1 - 4.8 7.6 12.8 0.93 9.9 8.7 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 Spore_coat_CotO PF14153.6 GBG84747.1 - 7.1 6.5 20.4 9.8 6.1 20.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Fasciclin PF02469.22 GBG84748.1 - 2.2e-12 47.3 0.5 2.9e-12 46.9 0.5 1.1 1 0 0 1 1 1 1 Fasciclin domain DUF659 PF04937.15 GBG84749.1 - 2.3e-06 27.5 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG84750.1 - 0.039 14.3 5.1 0.079 13.4 1.4 2.8 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG84751.1 - 4.1e-30 104.5 0.0 5.4e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84751.1 - 9.4e-13 48.2 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84751.1 - 1.4e-05 24.8 0.0 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG84753.1 - 1.9e-08 34.6 2.9 3.1e-08 33.9 2.9 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Fasciclin PF02469.22 GBG84753.1 - 3.5e-08 33.7 0.1 5.5e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Fasciclin domain Sas6_CC PF18594.1 GBG84753.1 - 0.078 12.8 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain Myb_DNA-binding PF00249.31 GBG84753.1 - 0.23 11.7 0.7 0.44 10.8 0.7 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Fasciclin PF02469.22 GBG84754.1 - 1.1e-08 35.4 0.1 1.4e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain Sas6_CC PF18594.1 GBG84754.1 - 0.017 14.9 0.2 0.046 13.5 0.2 1.7 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain Pkinase PF00069.25 GBG84756.1 - 2.1e-17 63.4 0.0 5.1e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84756.1 - 6.5e-16 58.4 0.0 2e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG84756.1 - 0.00088 20.0 1.1 0.058 14.3 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Fe_hyd_lg_C PF02906.14 GBG84757.1 - 0.3 10.7 3.1 0.42 10.2 3.1 1.3 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Phage_HK97_TLTM PF06120.11 GBG84757.1 - 1.4 8.0 12.2 2.8 7.0 11.8 1.5 1 1 1 2 2 2 0 Tail length tape measure protein RVT_1 PF00078.27 GBG84758.1 - 2.2e-29 102.6 0.0 3.3e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG84758.1 - 2.4e-11 43.4 0.0 4.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Fasciclin PF02469.22 GBG84759.1 - 1.3e-10 41.5 0.3 1.8e-10 41.2 0.3 1.1 1 0 0 1 1 1 1 Fasciclin domain CitMHS PF03600.16 GBG84760.1 - 3.1e-14 52.9 14.1 3.7e-14 52.6 14.1 1.1 1 0 0 1 1 1 1 Citrate transporter CitMHS PF03600.16 GBG84761.1 - 2.3e-14 53.3 6.9 2.9e-14 53.0 6.9 1.1 1 0 0 1 1 1 1 Citrate transporter RVT_1 PF00078.27 GBG84762.1 - 1.1e-06 28.4 4.3 1.4e-06 28.0 0.0 2.9 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84762.1 - 1.4e-06 28.9 0.0 3.2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84762.1 - 1.8e-05 25.2 0.0 4.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84762.1 - 2.4e-05 24.1 0.0 4.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84762.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG84762.1 - 0.0041 17.4 4.5 0.0083 16.4 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein Rab_bind PF16704.5 GBG84762.1 - 0.074 13.1 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Rab binding domain RPN2_C PF18004.1 GBG84762.1 - 3.9 7.4 7.0 8.3 6.3 7.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Rotamase_2 PF13145.6 GBG84762.1 - 7.2 7.5 10.4 8.7 7.2 7.2 2.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain RT_RNaseH_2 PF17919.1 GBG84763.1 - 5.3e-31 106.6 0.0 5.3e-16 58.5 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84763.1 - 4.3e-29 101.6 0.0 6.8e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84763.1 - 4.4e-29 100.9 0.0 8.3e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DNA_methylase PF00145.17 GBG84764.1 - 1.3e-11 44.4 0.1 8.1e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase UBA PF00627.31 GBG84764.1 - 0.0042 17.0 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain TFIIA PF03153.13 GBG84764.1 - 0.036 14.1 15.1 0.11 12.5 15.2 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA_deacylase PF04414.12 GBG84764.1 - 0.084 12.4 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase RhoGEF67_u1 PF16615.5 GBG84764.1 - 0.24 11.9 13.2 2.8 8.5 0.0 4.4 4 0 0 4 4 4 0 Unstructured region one on RhoGEF 6 and 7 Nop14 PF04147.12 GBG84764.1 - 0.36 9.0 18.0 0.59 8.3 18.0 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG84764.1 - 0.6 9.5 15.5 1 8.7 15.5 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG84764.1 - 1.7 7.1 16.6 2.7 6.5 16.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_3_Rpc31 PF11705.8 GBG84764.1 - 1.8 8.7 19.5 3.5 7.8 19.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RT_RNaseH_2 PF17919.1 GBG84765.1 - 7.4e-28 96.5 0.0 1.2e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84765.1 - 2.3e-25 88.9 0.0 4.6e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84765.1 - 8.2e-09 35.3 0.2 1.2e-08 34.8 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBA PF00627.31 GBG84766.1 - 2e-09 37.2 1.0 0.00025 20.9 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain DUF3173 PF11372.8 GBG84766.1 - 0.00048 19.9 0.0 0.31 10.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3173) HpaB PF03241.13 GBG84766.1 - 0.033 13.3 0.7 4.5 6.3 0.1 2.1 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal DUF1421 PF07223.11 GBG84766.1 - 0.045 13.6 0.0 4.3 7.2 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain (DUF1421) RNA_pol_3_Rpc31 PF11705.8 GBG84766.1 - 0.062 13.6 13.5 0.074 13.3 13.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2201_N PF13203.6 GBG84766.1 - 0.6 9.7 3.2 0.63 9.6 3.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain WRNPLPNID PF15017.6 GBG84766.1 - 4.9 8.1 19.1 0.38 11.7 0.4 2.4 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DNA_methylase PF00145.17 GBG84768.1 - 7e-15 55.2 0.1 6.8e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Nop14 PF04147.12 GBG84768.1 - 8.8 4.4 7.2 16 3.6 7.2 1.3 1 0 0 1 1 1 0 Nop14-like family HiaBD2 PF15403.6 GBG84769.1 - 0.00038 20.8 0.6 1.8 9.0 0.1 3.8 3 0 0 3 3 3 2 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) DUF1759 PF03564.15 GBG84769.1 - 0.016 15.1 17.5 16 5.4 0.0 8.2 8 2 3 11 11 11 0 Protein of unknown function (DUF1759) CNTF PF01110.17 GBG84769.1 - 0.035 13.5 21.2 0.69 9.3 0.1 7.2 7 2 2 9 9 9 0 Ciliary neurotrophic factor BLOC1_2 PF10046.9 GBG84769.1 - 0.063 13.6 43.2 2.3 8.6 0.1 10.5 10 2 1 11 11 11 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-CCHC PF00098.23 GBG84771.1 - 1.4e-05 24.9 2.1 1.4e-05 24.9 2.1 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG84771.1 - 0.011 15.4 1.6 0.036 13.8 1.6 1.9 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SAPS PF04499.15 GBG84772.1 - 0.00062 18.7 0.4 0.00062 18.7 0.4 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 GBG84772.1 - 0.46 10.5 1.3 0.57 10.2 1.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 GBG84772.1 - 2.7 6.8 6.0 3.7 6.4 6.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF913 PF06025.12 GBG84772.1 - 6.7 5.6 12.0 9 5.2 12.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDE_Tnp_4 PF13359.6 GBG84773.1 - 1.1e-25 90.1 0.0 3e-25 88.7 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84773.1 - 1.4e-08 34.6 0.0 2.6e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DUF2721 PF11026.8 GBG84773.1 - 0.00058 19.7 1.1 0.00058 19.7 1.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) Tweety PF04906.13 GBG84773.1 - 0.0026 16.5 1.5 0.0026 16.5 1.5 3.2 3 1 0 4 4 4 2 Tweety MARVEL PF01284.23 GBG84773.1 - 0.0026 17.8 2.1 0.082 12.9 2.6 2.3 1 1 0 1 1 1 1 Membrane-associating domain Taxilin PF09728.9 GBG84773.1 - 0.0062 15.8 10.3 0.015 14.5 10.3 1.5 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Retrotrans_gag PF03732.17 GBG84773.1 - 0.012 15.9 2.2 0.028 14.7 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein ABG_transport PF03806.13 GBG84773.1 - 0.013 13.7 0.1 0.026 12.7 0.1 1.4 1 0 0 1 1 1 0 AbgT putative transporter family SUR7 PF06687.12 GBG84773.1 - 0.042 13.5 6.2 0.036 13.7 1.3 2.2 2 0 0 2 2 2 0 SUR7/PalI family MCU PF04678.13 GBG84773.1 - 0.05 13.7 2.7 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Orf78 PF06024.12 GBG84773.1 - 0.052 13.9 1.3 0.32 11.3 0.1 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Exonuc_VII_L PF02601.15 GBG84773.1 - 0.077 12.6 3.7 0.15 11.6 3.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sensor PF13796.6 GBG84773.1 - 0.087 12.9 0.0 0.087 12.9 0.0 1.9 2 0 0 2 2 1 0 Putative sensor DUF2207 PF09972.9 GBG84773.1 - 1.1 8.0 5.6 0.62 8.8 1.9 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) RT_RNaseH_2 PF17919.1 GBG84777.1 - 2.5e-34 117.3 0.1 5.1e-34 116.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84777.1 - 1e-30 106.1 0.1 2.2e-30 105.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Alpha-L-AF_C PF06964.12 GBG84777.1 - 2.9e-24 86.1 0.2 5.5e-24 85.2 0.2 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain RVT_1 PF00078.27 GBG84777.1 - 3.1e-12 46.5 0.2 4.9e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Copine PF07002.16 GBG84778.1 - 1.5e-71 240.3 0.0 1.9e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 GBG84778.1 - 3.6e-13 49.7 0.0 4.3e-10 39.8 0.0 2.7 2 1 1 3 3 3 2 C2 domain vWA-TerF-like PF10138.9 GBG84778.1 - 0.00088 19.4 0.0 0.0025 18.0 0.0 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus Copine PF07002.16 GBG84779.1 - 1.4e-72 243.7 0.0 1.9e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GBG84779.1 - 1.9e-18 66.6 0.0 1.3e-12 47.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GBG84779.1 - 0.0003 20.9 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus HIT PF01230.23 GBG84780.1 - 3.9e-24 85.2 0.2 6.9e-24 84.4 0.2 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GBG84780.1 - 0.011 16.2 0.1 0.019 15.4 0.1 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Ribosomal_S30AE PF02482.19 GBG84780.1 - 0.1 13.4 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein Sporozoite_P67 PF05642.11 GBG84781.1 - 0.032 12.3 4.4 0.037 12.1 4.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WSK PF03832.13 GBG84781.1 - 2.8 7.7 6.3 1.7 8.4 0.4 2.6 2 0 0 2 2 2 0 WSK motif DUF4746 PF15928.5 GBG84781.1 - 2.9 7.2 6.9 3.5 7.0 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Copine PF07002.16 GBG84782.1 - 1.7e-69 233.6 0.0 2.5e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GBG84782.1 - 3.2e-19 69.1 0.0 3.6e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GBG84782.1 - 0.00031 20.9 0.0 0.00051 20.2 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Copine PF07002.16 GBG84784.1 - 1.2e-75 253.7 0.0 1.6e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GBG84784.1 - 3.1e-15 56.3 0.0 9.1e-10 38.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GBG84784.1 - 0.0017 18.5 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus AbiEii PF08843.11 GBG84784.1 - 0.1 12.5 0.0 4.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system DDE_Tnp_4 PF13359.6 GBG84788.1 - 2e-22 79.5 0.0 2.9e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84788.1 - 2.1e-12 47.1 0.0 4.7e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG84788.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG84788.1 - 0.14 11.8 0.1 3.8 7.1 0.0 2.5 2 1 0 2 2 2 0 Transposase DDE domain Copine PF07002.16 GBG84789.1 - 4.1e-70 235.6 0.0 5.8e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 GBG84789.1 - 3.2e-28 98.0 0.0 6.4e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GBG84789.1 - 0.0045 17.1 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF4317 PF14199.6 GBG84789.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) Copine PF07002.16 GBG84790.1 - 3.4e-70 235.9 0.0 4.8e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 GBG84790.1 - 4.9e-23 81.4 0.0 2.9e-12 46.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GBG84790.1 - 0.0039 17.3 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF4317 PF14199.6 GBG84790.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) AAA PF00004.29 GBG84791.1 - 3.1e-56 189.4 0.3 1.6e-39 135.4 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG84791.1 - 2.4e-12 46.5 0.0 6.2e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GBG84791.1 - 3.9e-10 40.4 1.1 0.0023 18.4 0.0 3.7 3 1 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.13 GBG84791.1 - 3.1e-08 33.2 0.1 0.0011 18.3 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_2 PF07724.14 GBG84791.1 - 4.6e-08 33.4 0.0 1.6e-05 25.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GBG84791.1 - 8e-08 32.4 0.3 0.00088 19.3 0.0 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GBG84791.1 - 8.7e-08 32.5 2.9 0.0036 17.6 0.2 4.1 2 2 0 3 3 3 1 AAA domain RuvB_N PF05496.12 GBG84791.1 - 1e-07 31.8 0.0 0.014 15.2 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 GBG84791.1 - 2.1e-06 27.6 0.0 0.0099 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 GBG84791.1 - 4.2e-06 26.6 0.1 0.025 14.3 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain CDC48_N PF02359.18 GBG84791.1 - 5.6e-06 26.4 0.0 7.6e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain IstB_IS21 PF01695.17 GBG84791.1 - 5.9e-06 26.1 0.0 0.17 11.6 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 GBG84791.1 - 1.5e-05 25.5 0.1 0.083 13.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 GBG84791.1 - 2.9e-05 23.5 0.4 0.0077 15.6 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GBG84791.1 - 3.2e-05 23.5 0.1 0.018 14.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 GBG84791.1 - 4.4e-05 23.7 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GBG84791.1 - 5.2e-05 23.6 0.0 0.11 12.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ATPase PF06745.13 GBG84791.1 - 0.00011 21.7 0.8 0.014 14.8 0.1 2.6 2 1 0 2 2 2 1 KaiC TsaE PF02367.17 GBG84791.1 - 0.00011 22.1 0.0 0.37 10.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 GBG84791.1 - 0.00012 22.2 0.0 0.42 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 GBG84791.1 - 0.00013 21.7 0.1 0.0033 17.2 0.0 2.9 3 0 0 3 3 3 1 Cell division protein 48 (CDC48), domain 2 PhoH PF02562.16 GBG84791.1 - 0.00017 21.1 0.1 0.18 11.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 GBG84791.1 - 0.00021 21.8 0.3 0.063 13.8 0.1 2.6 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 GBG84791.1 - 0.00031 20.7 6.3 0.23 11.4 0.1 3.7 4 0 0 4 4 3 1 NACHT domain Parvo_NS1 PF01057.17 GBG84791.1 - 0.00053 19.2 0.1 0.98 8.5 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 GBG84791.1 - 0.00055 19.7 0.6 0.95 9.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 GBG84791.1 - 0.0012 19.1 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 GBG84791.1 - 0.0014 18.0 0.1 0.76 9.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 GBG84791.1 - 0.0036 17.1 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 GBG84791.1 - 0.004 17.0 0.0 0.47 10.3 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GBG84791.1 - 0.0048 16.5 0.9 3.4 7.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 GBG84791.1 - 0.006 16.6 0.1 0.86 9.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 GBG84791.1 - 0.007 16.3 1.8 6.1 6.7 0.3 3.7 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 GBG84791.1 - 0.014 14.6 0.1 1.2 8.3 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 GBG84791.1 - 0.018 15.0 0.6 12 5.7 0.0 3.4 2 1 1 3 3 3 0 Rad17 P-loop domain TniB PF05621.11 GBG84791.1 - 0.023 14.1 0.3 5.8 6.3 0.1 3.3 2 1 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 GBG84791.1 - 0.053 13.3 0.3 12 5.8 0.0 3.0 3 0 0 3 3 2 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 GBG84791.1 - 0.06 13.1 0.0 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase IPT PF01745.16 GBG84791.1 - 0.079 12.3 0.2 0.97 8.8 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_17 PF13207.6 GBG84791.1 - 0.13 12.7 0.2 24 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GBG84791.1 - 0.41 11.1 1.4 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GBG84791.1 - 0.42 10.9 5.7 1.1 9.6 0.2 3.1 4 1 0 4 4 2 0 AAA domain PP2C PF00481.21 GBG84792.1 - 4.2e-50 170.8 0.0 5.2e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GBG84792.1 - 9e-06 25.7 0.1 0.0017 18.3 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GBG84792.1 - 0.00056 19.6 0.0 0.00084 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C FTHFS PF01268.19 GBG84793.1 - 0.06 11.5 1.5 0.072 11.3 1.5 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DUF682 PF05081.12 GBG84793.1 - 0.52 10.0 1.6 0.81 9.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF682) FAM60A PF15396.6 GBG84793.1 - 0.6 10.1 11.3 0.77 9.7 11.3 1.3 1 1 0 1 1 1 0 Protein Family FAM60A RHD3 PF05879.12 GBG84794.1 - 1.8e-229 763.7 2.0 1.4e-227 757.5 2.0 2.0 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 GBG84794.1 - 8.7e-05 22.6 0.0 0.00024 21.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GBG84794.1 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GBP PF02263.19 GBG84794.1 - 0.0021 17.3 0.2 0.0065 15.8 0.0 1.8 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain ATPase_2 PF01637.18 GBG84794.1 - 0.019 14.9 0.2 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 GBG84794.1 - 0.054 14.0 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Myb_DNA-bind_4 PF13837.6 GBG84795.1 - 1.8e-05 25.1 0.6 3.9e-05 24.0 0.3 1.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain ABC2_membrane_3 PF12698.7 GBG84796.1 - 0.066 12.3 4.4 0.073 12.2 4.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Methyltransf_11 PF08241.12 GBG84797.1 - 4.8e-21 75.2 0.0 2e-20 73.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG84797.1 - 7.6e-20 71.2 0.0 3.1e-19 69.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG84797.1 - 3.2e-18 66.2 0.0 7e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.10 GBG84797.1 - 4e-16 59.1 0.0 6.5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal CMAS PF02353.20 GBG84797.1 - 5.5e-14 52.1 0.0 7.8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GBG84797.1 - 2.5e-13 50.2 0.0 4.5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG84797.1 - 3.6e-10 40.5 0.0 1.4e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG84797.1 - 1.8e-07 30.8 0.0 3.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 GBG84797.1 - 3.3e-05 23.7 0.0 4.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 GBG84797.1 - 0.0027 17.8 0.0 0.0084 16.2 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 GBG84797.1 - 0.0033 17.0 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_9 PF08003.11 GBG84797.1 - 0.0055 15.7 0.0 0.0089 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DOT1 PF08123.13 GBG84797.1 - 0.035 13.6 0.0 0.25 10.8 0.0 2.0 1 1 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 GBG84797.1 - 0.05 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 GBG84797.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_5 PF01795.19 GBG84797.1 - 0.12 11.8 0.0 3.6 7.0 0.0 2.1 2 0 0 2 2 2 0 MraW methylase family Methyltransf_15 PF09445.10 GBG84797.1 - 0.15 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 GBG84797.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 GBG84798.1 - 3.5e-14 52.4 0.0 5.1e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GBG84798.1 - 5.5e-05 23.0 4.5 0.0001 22.2 4.5 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 GBG84798.1 - 0.0084 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 GBG84798.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 DbpA RNA binding domain Trypsin_2 PF13365.6 GBG84799.1 - 5.3e-31 108.5 0.8 1e-30 107.6 0.8 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GBG84799.1 - 7.7e-19 68.4 0.1 1.2e-18 67.7 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 GBG84799.1 - 2.7e-12 46.3 2.3 1.8e-11 43.7 0.6 3.1 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 GBG84799.1 - 2.6e-11 43.7 0.5 2.8e-10 40.4 0.1 2.7 2 1 0 2 2 2 1 PDZ domain PDZ PF00595.24 GBG84799.1 - 0.00019 21.7 0.1 0.00073 19.8 0.1 2.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 GBG84799.1 - 0.00022 21.1 0.4 0.00066 19.6 0.2 2.0 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 GBG84799.1 - 0.0012 17.6 1.0 0.1 11.2 0.3 2.2 2 0 0 2 2 2 2 Peptidase S46 DUF1043 PF06295.12 GBG84799.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) RRM_1 PF00076.22 GBG84800.1 - 7.3e-15 54.6 0.0 1.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GBG84800.1 - 1e-11 44.3 17.9 2.4e-06 27.4 5.5 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 GBG84800.1 - 9.2e-06 25.3 14.1 0.00035 20.2 3.0 2.6 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger RRM_5 PF13893.6 GBG84800.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.6 GBG84800.1 - 0.059 13.1 7.3 1 9.1 1.4 2.4 2 0 0 2 2 2 0 Zinc knuckle CLIP1_ZNF PF16641.5 GBG84800.1 - 0.066 13.1 1.5 0.15 12.0 1.5 1.7 1 0 0 1 1 1 0 CLIP1 zinc knuckle zf-CCHC_3 PF13917.6 GBG84800.1 - 0.14 12.1 17.9 0.11 12.5 2.2 3.2 2 1 1 3 3 3 0 Zinc knuckle HypA PF01155.19 GBG84800.1 - 0.42 10.7 1.1 0.72 9.9 1.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NFACT-R_1 PF05670.13 GBG84801.1 - 1.2e-43 148.2 0.0 1.7e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain peroxidase PF00141.23 GBG84802.1 - 4e-18 66.0 0.0 6.9e-05 22.6 0.0 3.9 3 1 1 4 4 4 3 Peroxidase Peptidase_M19 PF01244.21 GBG84802.1 - 0.11 11.6 1.2 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) GNAT_acetyltr_2 PF13718.6 GBG84802.1 - 0.25 10.7 3.9 0.52 9.7 3.9 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Lipoprotein_22 PF17294.2 GBG84802.1 - 0.42 10.2 8.6 1 9.0 8.6 1.6 1 0 0 1 1 1 0 Uncharacterised lipoprotein family FAM176 PF14851.6 GBG84802.1 - 4.3 7.0 8.7 9.9 5.8 8.7 1.5 1 0 0 1 1 1 0 FAM176 family dsRBD2 PF17842.1 GBG84802.1 - 8.8 6.5 8.1 6.3 7.0 0.1 3.0 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 Nt_Gln_amidase PF09764.9 GBG84804.1 - 5.8e-58 195.5 0.1 1.1e-31 109.9 0.0 2.6 2 0 0 2 2 2 2 N-terminal glutamine amidase RNF111_N PF15303.6 GBG84804.1 - 0.019 14.7 4.3 0.05 13.4 4.3 1.6 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus USP7_ICP0_bdg PF12436.8 GBG84805.1 - 1.3e-73 247.3 0.6 7.4e-73 244.8 0.1 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 GBG84805.1 - 1e-61 208.3 4.0 1.6e-58 197.8 0.1 3.3 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 GBG84805.1 - 3.4e-47 161.1 2.8 3.4e-47 161.1 2.8 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GBG84805.1 - 4.8e-24 85.5 0.4 2.1e-23 83.5 0.2 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 GBG84805.1 - 1.5e-19 70.2 0.7 4.2e-19 68.8 0.0 2.2 2 0 0 2 2 2 1 MATH domain ubiquitin PF00240.23 GBG84805.1 - 2.1e-05 24.2 0.1 0.09 12.5 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin family RA PF00788.23 GBG84805.1 - 0.0044 17.6 0.2 5.3 7.7 0.0 3.3 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Rad60-SLD PF11976.8 GBG84805.1 - 0.023 14.5 3.7 3.7 7.4 0.0 4.5 5 0 0 5 5 5 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 GBG84805.1 - 0.038 14.5 0.0 11 6.6 0.0 4.2 5 0 0 5 5 5 0 Nuclear pore localisation protein NPL4 Malt_amylase_C PF16657.5 GBG84805.1 - 0.063 13.4 0.0 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain Myb_DNA-bind_4 PF13837.6 GBG84806.1 - 1.3e-08 35.1 0.1 3.8e-08 33.6 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TerD PF02342.18 GBG84806.1 - 2.8e-07 30.2 0.0 5.5e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 TerD domain Dapper PF15268.6 GBG84807.1 - 0.11 11.3 14.6 0.17 10.7 14.6 1.2 1 0 0 1 1 1 0 Dapper SNN_linker PF09050.10 GBG84807.1 - 0.19 11.6 1.0 0.91 9.4 0.2 2.5 2 0 0 2 2 2 0 Stannin unstructured linker Utp14 PF04615.13 GBG84807.1 - 0.34 9.4 35.1 0.53 8.8 35.1 1.2 1 0 0 1 1 1 0 Utp14 protein MORN PF02493.20 GBG84808.1 - 1e-18 66.0 19.7 5.8e-09 35.3 3.1 5.7 5 0 0 5 5 5 5 MORN repeat Snapin_Pallidin PF14712.6 GBG84809.1 - 0.061 13.8 9.3 0.051 14.0 3.9 2.7 1 1 1 2 2 2 0 Snapin/Pallidin DUF4407 PF14362.6 GBG84809.1 - 0.09 12.1 2.4 0.2 11.0 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 GBG84809.1 - 0.74 10.2 19.1 0.45 10.9 0.8 3.7 1 1 2 3 3 3 0 Csm1 N-terminal domain ARTD15_N PF18084.1 GBG84809.1 - 1.3 9.4 4.1 14 6.0 0.2 3.6 2 1 2 4 4 4 0 ARTD15 N-terminal domain Pectinesterase PF01095.19 GBG84810.1 - 3.9e-73 245.8 1.6 4.9e-73 245.5 1.6 1.1 1 0 0 1 1 1 1 Pectinesterase VIR_N PF15912.5 GBG84810.1 - 1.2 8.7 4.5 2 7.9 4.5 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal DDE_Tnp_4 PF13359.6 GBG84811.1 - 6.3e-16 58.4 0.0 6e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84811.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 GBG84812.1 - 1.2e-25 90.0 0.0 1.8e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84812.1 - 2.2e-12 47.0 0.0 3.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84812.1 - 7.2e-05 22.5 0.3 0.001 18.8 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG84812.1 - 0.077 13.4 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain ATP-synt_G PF04718.15 GBG84813.1 - 1.9e-20 73.5 0.0 2.3e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit LEA_2 PF03168.13 GBG84814.1 - 3.5e-27 94.9 0.0 5.7e-13 49.3 0.0 2.3 2 0 0 2 2 2 2 Late embryogenesis abundant protein Sif PF06767.11 GBG84814.1 - 0.14 11.1 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Sif protein Topoisom_I PF01028.20 GBG84815.1 - 1e-84 283.4 0.1 1e-84 283.4 0.1 1.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 GBG84815.1 - 5.1e-79 264.7 2.7 9.6e-79 263.8 2.7 1.4 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 GBG84815.1 - 1.1e-34 118.1 0.9 1.1e-34 118.1 0.9 2.4 2 1 1 3 3 3 1 C-terminal topoisomerase domain BET PF17035.5 GBG84815.1 - 0.05 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Spc7 PF08317.11 GBG84815.1 - 3 6.7 9.4 2.5 6.9 0.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein RCC1 PF00415.18 GBG84816.1 - 1.2e-66 221.2 30.8 2.1e-12 47.4 1.5 9.9 9 1 0 9 9 9 9 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG84816.1 - 2.3e-32 110.1 45.7 5.8e-09 35.5 3.6 8.1 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Myb_DNA-bind_4 PF13837.6 GBG84817.1 - 4.9e-06 26.8 1.0 8.2e-06 26.1 0.5 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG84817.1 - 0.0074 16.3 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG84818.1 - 7.1e-28 97.3 0.0 1e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84818.1 - 6.5e-15 55.3 0.0 1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84818.1 - 6e-05 22.8 1.9 0.24 11.0 0.9 2.6 2 1 0 2 2 2 2 Transposase DDE domain DUF1365 PF07103.11 GBG84819.1 - 1.3e-38 133.0 0.2 3.6e-22 79.2 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1365) Acetyltransf_10 PF13673.7 GBG84821.1 - 3e-19 69.2 0.0 3.8e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GBG84821.1 - 2.2e-12 47.2 0.0 3.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GBG84821.1 - 4.7e-12 46.2 0.0 6.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GBG84821.1 - 4e-06 26.7 0.0 6.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_5 PF13444.6 GBG84821.1 - 0.00013 22.6 0.1 0.0011 19.6 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GBG84821.1 - 0.0018 18.4 0.0 0.0055 16.8 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain AT_hook PF02178.19 GBG84822.1 - 0.55 10.3 9.3 0.14 12.2 3.6 2.5 2 0 0 2 2 2 0 AT hook motif DUF659 PF04937.15 GBG84823.1 - 7.6e-16 58.3 0.2 4.8e-15 55.7 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG84823.1 - 3.1e-05 23.7 0.1 0.0002 21.1 0.2 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Pectinesterase PF01095.19 GBG84824.1 - 3.7e-74 249.2 1.2 4.6e-74 248.8 1.2 1.1 1 0 0 1 1 1 1 Pectinesterase Pectinesterase PF01095.19 GBG84826.1 - 4.4e-75 252.2 4.0 5.7e-75 251.8 4.0 1.1 1 0 0 1 1 1 1 Pectinesterase Pectate_lyase_3 PF12708.7 GBG84826.1 - 0.0071 16.2 0.3 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 Pectate lyase superfamily protein Glycoprotein_B PF00606.18 GBG84826.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain Golgin_A5 PF09787.9 GBG84827.1 - 1.7e-22 80.3 50.6 7e-21 75.0 21.0 3.1 1 1 2 3 3 3 2 Golgin subfamily A member 5 Fib_alpha PF08702.10 GBG84827.1 - 0.00043 20.5 2.5 0.00043 20.5 2.5 3.7 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family Leu_zip PF15294.6 GBG84827.1 - 1.3 8.5 48.1 0.42 10.1 22.2 3.1 1 1 2 3 3 3 0 Leucine zipper ATG16 PF08614.11 GBG84827.1 - 6.7 6.9 72.0 2.5 8.3 29.1 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PKD_3 PF16820.5 GBG84828.1 - 0.15 11.8 6.6 15 5.4 0.0 4.6 4 1 1 5 5 5 0 PKD-like domain DUF5129 PF17173.4 GBG84828.1 - 0.18 10.9 5.5 2.6 7.1 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF5129) ChW PF07538.11 GBG84828.1 - 0.35 10.8 13.7 13 5.8 0.3 5.1 5 0 0 5 5 5 0 Clostridial hydrophobic W CLASP_N PF12348.8 GBG84829.1 - 1.9e-20 73.4 1.2 6.1e-06 26.0 0.2 5.8 6 1 0 6 6 6 3 CLASP N terminal HEAT_2 PF13646.6 GBG84829.1 - 1.6e-13 50.9 18.3 0.016 15.5 0.2 9.4 9 1 1 10 10 9 5 HEAT repeats HEAT PF02985.22 GBG84829.1 - 2.1e-06 27.5 24.6 0.057 13.7 0.2 11.8 15 0 0 15 15 14 2 HEAT repeat Cnd1 PF12717.7 GBG84829.1 - 6.1e-06 26.4 13.5 0.13 12.3 0.0 6.9 6 2 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GBG84829.1 - 0.00045 20.8 0.8 51 4.6 0.1 5.9 6 1 1 7 7 6 0 Vacuolar 14 Fab1-binding region Ribosomal_L22 PF00237.19 GBG84829.1 - 0.0077 16.5 0.4 6.4 7.1 0.0 3.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DCB PF16213.5 GBG84829.1 - 0.03 14.0 0.7 1 9.0 0.0 3.4 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 V-ATPase_H_C PF11698.8 GBG84829.1 - 0.041 14.0 2.6 3 8.0 0.0 4.7 5 0 0 5 5 5 0 V-ATPase subunit H HEAT_EZ PF13513.6 GBG84829.1 - 0.056 14.0 14.3 44 4.7 0.0 8.2 7 1 1 8 8 8 0 HEAT-like repeat TAN PF11640.8 GBG84829.1 - 0.062 13.4 5.5 16 5.6 0.0 5.8 7 0 0 7 7 7 0 Telomere-length maintenance and DNA damage repair VHS PF00790.19 GBG84829.1 - 0.11 12.4 0.1 56 3.6 0.0 4.2 4 0 0 4 4 4 0 VHS domain MMS19_N PF14500.6 GBG84829.1 - 0.22 11.0 6.9 15 5.1 0.1 5.9 6 1 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.8 GBG84830.1 - 1.9e-20 73.4 1.2 6e-06 26.0 0.2 5.8 6 1 0 6 6 6 3 CLASP N terminal HEAT_2 PF13646.6 GBG84830.1 - 4.1e-13 49.5 19.8 0.016 15.5 0.2 9.4 8 2 1 10 10 9 5 HEAT repeats HEAT PF02985.22 GBG84830.1 - 2e-06 27.6 24.6 0.057 13.7 0.2 11.8 15 0 0 15 15 14 2 HEAT repeat Cnd1 PF12717.7 GBG84830.1 - 6e-06 26.4 13.6 0.13 12.3 0.0 6.9 6 2 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GBG84830.1 - 0.00043 20.8 0.8 51 4.6 0.1 6.0 6 1 1 7 7 6 0 Vacuolar 14 Fab1-binding region Ribosomal_L22 PF00237.19 GBG84830.1 - 0.0076 16.5 0.4 6.3 7.1 0.0 3.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DCB PF16213.5 GBG84830.1 - 0.03 14.0 0.7 1 9.0 0.0 3.4 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 V-ATPase_H_C PF11698.8 GBG84830.1 - 0.04 14.0 2.6 3 8.0 0.0 4.7 5 0 0 5 5 5 0 V-ATPase subunit H HEAT_EZ PF13513.6 GBG84830.1 - 0.054 14.0 14.3 44 4.7 0.0 8.2 7 1 1 8 8 8 0 HEAT-like repeat TAN PF11640.8 GBG84830.1 - 0.061 13.5 5.5 16 5.6 0.0 5.9 7 0 0 7 7 7 0 Telomere-length maintenance and DNA damage repair VHS PF00790.19 GBG84830.1 - 0.1 12.4 0.1 56 3.6 0.0 4.3 4 0 0 4 4 4 0 VHS domain MMS19_N PF14500.6 GBG84830.1 - 0.22 11.1 6.9 15 5.1 0.1 5.9 6 1 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II NADHdh_A3 PF14987.6 GBG84832.1 - 0.002 18.4 0.6 0.0023 18.2 0.6 1.3 1 1 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 CAC1F_C PF16885.5 GBG84833.1 - 0.45 10.1 4.0 0.55 9.9 4.0 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term NDUF_C2 PF06374.11 GBG84834.1 - 0.09 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Diphthamide_syn PF01866.17 GBG84835.1 - 7.7e-112 373.6 0.0 1e-111 373.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Gla PF00594.20 GBG84835.1 - 0.27 11.5 2.0 0.6 10.4 2.0 1.5 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain HTH_23 PF13384.6 GBG84837.1 - 0.029 14.2 0.7 0.056 13.3 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 GBG84837.1 - 0.19 11.9 0.2 0.31 11.2 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DDE_Tnp_4 PF13359.6 GBG84838.1 - 4.3e-29 101.2 0.0 2.1e-27 95.7 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84838.1 - 1.1e-09 38.2 0.0 2.9e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84838.1 - 0.0095 15.6 0.4 1.8 8.1 0.1 3.1 3 1 0 3 3 3 2 Transposase DDE domain PBP3 PF18056.1 GBG84840.1 - 0.23 11.6 2.0 0.38 10.9 1.2 1.7 2 0 0 2 2 2 0 Penicillin Binding Protein 3 Domain zf-CCHC PF00098.23 GBG84842.1 - 5.2e-06 26.3 1.0 9.3e-06 25.5 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG84842.1 - 0.0094 15.9 1.3 0.04 13.9 1.3 2.1 1 0 0 1 1 1 1 Zinc knuckle DDRGK PF09756.9 GBG84842.1 - 0.018 14.7 14.2 0.046 13.3 14.2 1.7 1 0 0 1 1 1 0 DDRGK domain VIT1 PF01988.19 GBG84842.1 - 0.43 10.4 1.0 0.63 9.9 1.0 1.3 1 0 0 1 1 1 0 VIT family ABC2_membrane_3 PF12698.7 GBG84843.1 - 6.4 5.8 4.5 8.8 5.3 4.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Hydantoinase_B PF02538.14 GBG84844.1 - 1.6e-33 116.0 5.2 1.9e-33 115.7 5.2 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase DUF3439 PF11921.8 GBG84845.1 - 0.065 13.2 4.5 0.21 11.6 4.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CCG PF02754.16 GBG84845.1 - 0.32 11.2 1.1 11 6.3 0.2 2.6 2 0 0 2 2 2 0 Cysteine-rich domain MIP-T3_C PF17749.1 GBG84845.1 - 2.4 8.1 8.4 0.31 11.0 3.7 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Exo_endo_phos PF03372.23 GBG84846.1 - 6.9e-06 25.7 0.1 1.4e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NDUFB10 PF10249.9 GBG84846.1 - 0.00082 19.9 0.0 0.0022 18.5 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Exo_endo_phos_2 PF14529.6 GBG84846.1 - 0.0039 17.0 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TPP_enzyme_N PF02776.18 GBG84847.1 - 3e-41 140.9 0.2 3e-41 140.9 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GBG84847.1 - 4.9e-33 113.8 0.1 9.1e-33 112.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GBG84847.1 - 2.1e-09 37.3 0.1 4.9e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_C PF02775.21 GBG84848.1 - 1.2e-10 41.4 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AMP-binding PF00501.28 GBG84849.1 - 6.9e-97 324.7 0.0 8.8e-97 324.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GBG84849.1 - 4e-18 66.2 4.8 5.8e-18 65.6 1.3 2.6 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 GBG84849.1 - 0.0018 17.2 0.0 0.035 13.0 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RIB43A PF05914.12 GBG84851.1 - 1.8e-48 165.2 29.9 2.1e-48 165.0 29.9 1.0 1 0 0 1 1 1 1 RIB43A Nbs1_C PF08599.10 GBG84851.1 - 4.8 7.4 6.9 1.6 8.9 0.3 2.6 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 ERCC4 PF02732.15 GBG84852.1 - 3.7e-21 75.9 0.0 6.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain DUF913 PF06025.12 GBG84852.1 - 0.27 10.2 2.5 0.42 9.5 2.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 GBG84852.1 - 0.45 10.3 12.3 0.76 9.6 12.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GBG84852.1 - 1.1 7.4 18.3 1.6 6.9 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG84852.1 - 1.5 6.9 27.1 2.1 6.5 27.1 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG84852.1 - 1.7 8.3 16.4 2.2 8.0 15.7 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 GBG84852.1 - 2.6 8.2 36.9 0.091 13.0 28.3 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.12 GBG84852.1 - 2.8 7.3 21.3 4.3 6.6 21.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 GBG84852.1 - 2.8 7.3 27.0 4.1 6.7 27.0 1.2 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 GBG84852.1 - 3.9 6.6 4.2 5.8 6.0 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 GBG84852.1 - 5.6 6.2 22.3 8.2 5.7 22.3 1.1 1 0 0 1 1 1 0 BUD22 RQC PF09382.10 GBG84854.1 - 1.1e-24 86.4 0.0 2.8e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 GBG84854.1 - 8.9e-23 80.9 0.0 1.5e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG84854.1 - 6.2e-20 71.6 0.0 1.5e-17 63.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HTH_40 PF14493.6 GBG84854.1 - 3.1e-19 69.2 0.0 9.8e-19 67.6 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain RecQ_Zn_bind PF16124.5 GBG84854.1 - 6.1e-12 46.1 4.2 2.5e-11 44.1 4.2 2.2 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 GBG84854.1 - 0.00029 20.9 0.0 0.00029 20.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PPR_2 PF13041.6 GBG84856.1 - 2.2e-62 207.0 13.7 6.2e-10 39.1 0.0 11.7 4 3 7 11 11 11 11 PPR repeat family PPR PF01535.20 GBG84856.1 - 1.4e-59 194.3 30.1 2.4e-06 27.4 0.1 13.3 13 0 0 13 13 13 11 PPR repeat PPR_1 PF12854.7 GBG84856.1 - 1e-43 146.7 1.1 1.4e-06 27.9 0.0 12.0 12 0 0 12 12 12 7 PPR repeat PPR_3 PF13812.6 GBG84856.1 - 3.8e-38 129.4 0.0 1e-13 51.1 0.0 7.6 5 1 3 8 8 8 8 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG84856.1 - 2.1e-28 99.2 1.2 1.2e-11 44.4 0.0 4.2 2 2 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GBG84856.1 - 0.00095 19.8 17.2 0.74 10.8 0.0 8.6 8 3 3 11 11 11 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG84856.1 - 0.0026 17.7 0.7 7.1 6.9 0.0 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG84856.1 - 0.009 16.3 11.2 0.032 14.5 0.9 5.6 8 0 0 8 8 7 1 Tetratricopeptide repeat Exog_C PF18026.1 GBG84856.1 - 0.013 15.5 3.1 6.9 6.8 0.0 4.5 5 0 0 5 5 5 0 Endo/exonuclease (EXOG) C-terminal domain RPN7 PF10602.9 GBG84856.1 - 0.03 14.0 3.6 0.34 10.6 0.8 3.2 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Rabaptin PF03528.15 GBG84856.1 - 0.033 12.9 0.0 0.072 11.8 0.0 1.5 1 0 0 1 1 1 0 Rabaptin SPOR PF05036.13 GBG84856.1 - 0.079 13.3 6.7 0.19 12.1 0.2 4.3 5 0 0 5 5 4 0 Sporulation related domain DUF3368 PF11848.8 GBG84856.1 - 0.1 12.4 0.0 3.6 7.4 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3368) MRP-S27 PF10037.9 GBG84856.1 - 0.14 11.0 0.0 0.35 9.7 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_6 PF13174.6 GBG84856.1 - 0.73 10.6 11.0 47 4.9 0.1 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Nmad5 PF18757.1 GBG84857.1 - 1.7 8.8 8.6 4.4 7.5 8.6 1.6 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 BET PF17035.5 GBG84858.1 - 5.6e-21 74.5 0.9 1e-20 73.6 0.9 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 GBG84858.1 - 2.3e-17 62.8 0.0 3.5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain EF-hand_7 PF13499.6 GBG84859.1 - 2.2e-20 72.9 0.8 5.1e-15 55.7 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG84859.1 - 1e-17 62.3 2.8 3.6e-09 35.5 0.3 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GBG84859.1 - 6.4e-15 53.9 0.9 5.3e-08 32.0 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GBG84859.1 - 6.6e-15 53.7 1.4 1.8e-09 36.7 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GBG84859.1 - 3.8e-11 42.7 4.4 6.4e-09 35.5 0.3 3.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 GBG84859.1 - 0.00095 19.4 0.0 0.0022 18.3 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 GBG84859.1 - 0.0048 17.1 1.6 0.024 14.8 1.7 2.0 1 1 0 1 1 1 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 GBG84859.1 - 0.0067 16.7 0.2 0.027 14.8 0.0 1.8 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Lip_prot_lig_C PF10437.9 GBG84859.1 - 0.04 13.9 0.1 0.74 9.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus EF-hand_4 PF12763.7 GBG84859.1 - 0.053 13.5 0.3 0.097 12.6 0.1 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Rib_5-P_isom_A PF06026.14 GBG84861.1 - 3.6e-63 212.3 0.0 4.6e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 GBG84861.1 - 0.00014 21.8 2.2 0.0075 16.2 0.1 3.1 3 0 0 3 3 3 1 DeoR C terminal sensor domain Integrase_H2C2 PF17921.1 GBG84862.1 - 5.9e-16 58.3 0.1 2.5e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG84862.1 - 1.5e-12 47.5 0.1 2.4e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG84862.1 - 6.6e-11 42.4 0.0 2.3e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG84862.1 - 7.9e-11 41.7 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG84862.1 - 2.1e-09 37.6 0.3 4.8e-09 36.5 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG84862.1 - 2.2e-05 24.6 0.0 5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG84862.1 - 0.096 12.5 0.1 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase-like Smr PF01713.21 GBG84863.1 - 0.00025 21.4 0.4 0.00089 19.6 0.1 2.0 2 0 0 2 2 2 1 Smr domain PPR_2 PF13041.6 GBG84865.1 - 5.7e-68 224.9 21.6 3.1e-14 52.9 0.0 10.4 5 3 5 10 10 10 8 PPR repeat family PPR_3 PF13812.6 GBG84865.1 - 5.1e-65 215.4 1.8 9.4e-14 51.2 0.2 7.9 6 1 1 7 7 7 7 Pentatricopeptide repeat domain PPR PF01535.20 GBG84865.1 - 9e-50 163.5 28.6 8.4e-07 28.8 0.1 12.7 12 1 0 12 12 12 8 PPR repeat PPR_1 PF12854.7 GBG84865.1 - 7.7e-46 153.5 28.1 3.2e-07 29.9 0.0 11.6 12 0 0 12 12 12 10 PPR repeat PPR_long PF17177.4 GBG84865.1 - 5.9e-34 117.3 0.6 1.4e-15 57.3 0.0 5.1 3 2 3 6 6 6 5 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 GBG84865.1 - 0.018 14.2 0.1 3 6.9 0.1 3.8 4 1 1 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF572 PF04502.13 GBG84866.1 - 3e-06 27.1 2.5 5.4e-06 26.3 2.4 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF572 PF04502.13 GBG84867.1 - 2.5e-06 27.4 1.9 5.1e-06 26.4 2.0 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) Abhydrolase_1 PF00561.20 GBG84868.1 - 1.1e-10 41.6 0.0 7.4e-09 35.6 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Acyltransferase PF01553.21 GBG84868.1 - 5.7e-07 29.2 0.0 1.4e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase Abhydrolase_6 PF12697.7 GBG84868.1 - 7.1e-07 30.0 0.1 1.7e-06 28.8 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DAGAT PF03982.13 GBG84868.1 - 1.2e-06 27.7 0.0 2.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Hydrolase_4 PF12146.8 GBG84868.1 - 5.9e-06 25.7 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 GBG84868.1 - 0.078 12.9 0.0 0.7 9.8 0.0 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1664 PF07889.12 GBG84869.1 - 0.011 15.7 2.6 0.011 15.7 2.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Protocadherin PF08374.11 GBG84869.1 - 0.066 13.2 2.7 0.16 11.9 2.7 1.6 1 0 0 1 1 1 0 Protocadherin DNA_pack_N PF02500.15 GBG84869.1 - 0.073 12.9 0.1 0.073 12.9 0.1 2.4 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus MAP7 PF05672.11 GBG84869.1 - 0.68 9.6 46.6 0.046 13.4 25.4 2.4 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Pex24p PF06398.11 GBG84869.1 - 1.2 8.1 7.3 2.5 7.0 7.3 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin LMBR1 PF04791.16 GBG84869.1 - 1.6 7.5 8.2 2.6 6.8 8.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Myc_N PF01056.18 GBG84869.1 - 3.2 7.6 15.9 3.4 7.5 10.9 2.2 2 0 0 2 2 2 0 Myc amino-terminal region ATP-synt_B PF00430.18 GBG84870.1 - 3.8e-16 59.4 9.3 3.8e-16 59.4 9.3 2.8 3 0 0 3 3 3 1 ATP synthase B/B' CF(0) Apolipoprotein PF01442.18 GBG84870.1 - 0.00045 20.1 12.5 0.00045 20.1 12.5 1.8 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain UPF0242 PF06785.11 GBG84870.1 - 0.00061 19.9 2.5 0.00087 19.5 2.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Mt_ATP-synt_B PF05405.14 GBG84870.1 - 0.001 18.7 2.4 0.0015 18.2 2.4 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF948 PF06103.11 GBG84870.1 - 0.0061 16.8 3.7 0.2 11.9 0.0 2.9 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 GBG84870.1 - 0.0075 16.6 10.2 0.016 15.5 9.2 1.9 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 GBG84870.1 - 0.0079 16.4 4.7 0.016 15.4 4.7 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family PIN_8 PF18476.1 GBG84870.1 - 0.013 15.4 5.6 0.021 14.7 5.6 1.2 1 0 0 1 1 1 0 PIN like domain LMP PF04778.12 GBG84870.1 - 0.024 14.5 4.9 0.06 13.3 4.9 1.6 1 1 0 1 1 1 0 LMP repeated region YojJ PF10372.9 GBG84870.1 - 0.041 14.0 3.0 1.1 9.4 0.1 2.9 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus Phage_GP20 PF06810.11 GBG84870.1 - 0.11 12.3 9.4 0.17 11.7 9.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Muted PF14942.6 GBG84870.1 - 0.14 12.5 6.0 0.19 12.1 5.4 1.5 2 0 0 2 2 1 0 Organelle biogenesis, Muted-like protein Fez1 PF06818.15 GBG84870.1 - 0.15 12.5 8.0 0.27 11.6 8.0 1.3 1 0 0 1 1 1 0 Fez1 RasGAP PF00616.19 GBG84870.1 - 0.17 11.6 0.5 0.22 11.2 0.5 1.2 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase 7TMR-HDED PF07697.11 GBG84870.1 - 0.2 11.8 7.2 0.38 10.8 7.2 1.4 1 0 0 1 1 1 0 7TM-HD extracellular DUF4407 PF14362.6 GBG84870.1 - 0.24 10.7 7.6 0.61 9.4 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSCB_C PF07743.13 GBG84870.1 - 0.48 10.9 13.0 7 7.2 3.4 2.8 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Tho2 PF11262.8 GBG84870.1 - 0.71 9.0 3.5 1.1 8.4 3.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1451 PF07295.11 GBG84870.1 - 1.1 9.3 8.6 3.2 7.8 8.6 1.7 1 1 0 1 1 1 0 Zinc-ribbon containing domain Atg14 PF10186.9 GBG84870.1 - 9.4 5.2 8.6 15 4.5 8.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IF-2 PF11987.8 GBG84871.1 - 2.5e-27 95.1 3.4 2.7e-27 95.0 0.2 2.5 3 0 0 3 3 3 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 GBG84871.1 - 5.9e-24 84.7 1.4 6.3e-20 71.5 0.6 3.3 2 1 1 3 3 3 3 Elongation factor Tu GTP binding domain IF2_N PF04760.15 GBG84871.1 - 7.4e-10 38.5 0.5 2.1e-09 37.1 0.2 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 GBG84871.1 - 0.03 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase IF-2 PF11987.8 GBG84872.1 - 2.4e-27 95.1 3.4 2.5e-27 95.0 0.2 2.5 3 0 0 3 3 3 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 GBG84872.1 - 1.3e-21 77.0 0.8 7e-20 71.4 0.6 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain IF2_N PF04760.15 GBG84872.1 - 6.8e-10 38.6 0.5 2e-09 37.1 0.2 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 GBG84872.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase RVT_1 PF00078.27 GBG84873.1 - 1.9e-27 96.3 0.1 6.2e-27 94.6 0.1 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84873.1 - 5e-23 81.0 0.0 2.5e-22 78.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84873.1 - 6.5e-23 81.0 0.0 2.9e-22 78.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG84873.1 - 1.7e-08 34.3 0.0 6.3e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG84873.1 - 1.8e-08 34.8 0.0 1.1e-05 25.9 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84873.1 - 1.8e-07 31.7 0.0 0.00057 20.5 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease Retrotrans_gag PF03732.17 GBG84873.1 - 8.6e-07 29.1 3.0 0.036 14.3 0.4 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG84873.1 - 0.0091 15.8 0.0 0.084 12.6 0.0 2.5 3 0 0 3 3 3 1 Retroviral aspartyl protease DUF3672 PF12421.8 GBG84873.1 - 0.18 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III protein Med9 PF07544.13 GBG84874.1 - 0.85 9.7 15.5 0.32 11.1 1.0 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Vfa1 PF08432.10 GBG84874.1 - 1.3 9.4 16.8 1.6 9.0 16.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Med19 PF10278.9 GBG84874.1 - 2.1 8.3 13.5 3 7.7 13.5 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PA26 PF04636.13 GBG84874.1 - 2.2 7.1 11.5 2.5 6.9 11.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DDHD PF02862.17 GBG84874.1 - 3.6 7.7 8.2 3.9 7.6 8.2 1.1 1 0 0 1 1 1 0 DDHD domain FtsK_SpoIIIE PF01580.18 GBG84874.1 - 3.7 6.8 6.2 4.6 6.5 3.8 1.8 1 1 1 2 2 2 0 FtsK/SpoIIIE family DUF4407 PF14362.6 GBG84874.1 - 7.4 5.8 17.4 9 5.6 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 GBG84874.1 - 8 5.6 5.4 8.8 5.4 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3807 PF12720.7 GBG84874.1 - 9.3 6.5 16.7 12 6.1 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) TP53IP5 PF15331.6 GBG84874.1 - 9.9 6.2 15.2 11 6.1 15.2 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF659 PF04937.15 GBG84875.1 - 4.5e-40 137.0 0.0 1.1e-39 135.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG84875.1 - 6.2e-07 29.1 0.3 3.3e-06 26.8 0.4 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG84875.1 - 0.021 14.7 25.5 0.04 13.8 3.3 3.8 3 0 0 3 3 3 0 AT hook motif Tho2 PF11262.8 GBG84875.1 - 0.12 11.6 0.2 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 RVT_1 PF00078.27 GBG84876.1 - 5.4e-28 98.0 0.0 1.1e-27 97.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG84876.1 - 8.5e-20 70.6 0.1 1.9e-19 69.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG84876.1 - 6.4e-12 45.7 0.1 1.4e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84876.1 - 2.9e-07 30.7 0.0 7.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG84876.1 - 6.8e-06 26.0 0.0 0.00033 20.6 0.0 2.4 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase Tudor-knot PF11717.8 GBG84876.1 - 0.0001 22.1 0.0 0.00029 20.7 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG84876.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Myosin_TH1 PF06017.13 GBG84878.1 - 4.5e-33 114.5 0.2 5.2e-33 114.3 0.2 1.0 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding RAMP4 PF06624.12 GBG84881.1 - 1.3e-26 92.4 0.6 1.4e-26 92.3 0.6 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF1206 PF06724.11 GBG84881.1 - 0.017 15.2 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) RT_RNaseH_2 PF17919.1 GBG84882.1 - 3.7e-24 84.7 0.0 6.4e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84882.1 - 4.5e-22 78.3 0.0 8.6e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84882.1 - 0.0038 16.8 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CTP_synth_N PF06418.14 GBG84883.1 - 1.5e-126 421.2 0.1 2.1e-126 420.7 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 GBG84883.1 - 1.2e-56 191.6 0.0 1e-55 188.5 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GBG84883.1 - 6e-05 22.9 0.1 0.0002 21.2 0.0 2.0 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 GBG84883.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RT_RNaseH_2 PF17919.1 GBG84886.1 - 1.8e-33 114.6 0.1 4.2e-33 113.3 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84886.1 - 3.2e-29 101.3 1.1 5.8e-29 100.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84886.1 - 9e-20 71.1 0.0 1.7e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tom37 PF10568.9 GBG84886.1 - 7.5e-17 61.8 0.0 2.3e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein rve PF00665.26 GBG84886.1 - 1.7e-14 54.0 0.1 4.9e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain GST_N_4 PF17172.4 GBG84886.1 - 1.7e-13 51.1 0.0 5.4e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GBG84886.1 - 4.8e-13 48.7 0.1 1.7e-08 34.1 0.0 2.9 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Integrase_H2C2 PF17921.1 GBG84886.1 - 1.8e-07 31.2 0.0 3.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain GST_C_2 PF13410.6 GBG84886.1 - 0.013 15.6 0.0 25 5.0 0.0 4.2 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain U1snRNP70_N PF12220.8 GBG84886.1 - 0.36 11.5 2.5 15 6.3 0.2 2.9 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Asp_protease_2 PF13650.6 GBG84887.1 - 4e-07 30.6 0.0 2e-06 28.4 0.0 2.2 2 0 0 2 2 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84887.1 - 7.9e-07 29.6 0.0 3.8e-06 27.4 0.0 2.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84887.1 - 1.3e-06 28.2 0.0 3.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Cob_adeno_trans PF01923.18 GBG84887.1 - 0.0012 19.0 3.5 0.079 13.1 0.1 2.8 2 1 1 3 3 3 1 Cobalamin adenosyltransferase Asp_protease PF09668.10 GBG84887.1 - 0.0017 18.2 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG84887.1 - 0.018 15.3 9.9 12 6.3 0.0 5.4 5 0 0 5 5 5 0 Retrotransposon gag protein SKA2 PF16740.5 GBG84887.1 - 0.031 14.0 3.2 5.2 6.9 0.1 3.2 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Dynamitin PF04912.14 GBG84887.1 - 0.055 12.8 9.7 0.13 11.6 0.6 2.2 1 1 1 2 2 2 0 Dynamitin Baculo_PEP_C PF04513.12 GBG84887.1 - 0.088 12.8 2.9 8.8 6.4 0.2 2.7 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 GBG84887.1 - 0.19 12.3 13.7 17 6.1 0.1 4.8 4 0 0 4 4 4 0 SlyX GerPC PF10737.9 GBG84887.1 - 0.48 10.5 1.8 18 5.4 0.0 3.2 3 0 0 3 3 3 0 Spore germination protein GerPC ABC_tran_CTD PF16326.5 GBG84887.1 - 2.9 8.2 11.5 16 5.8 0.0 4.5 5 0 0 5 5 5 0 ABC transporter C-terminal domain DASH_Hsk3 PF08227.11 GBG84887.1 - 6 7.3 9.5 16 6.0 0.5 3.3 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like CLZ PF16526.5 GBG84887.1 - 7.4 7.0 9.2 8.9 6.8 0.4 4.4 4 2 2 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 GBG84887.1 - 8.9 6.2 12.5 12 5.7 0.1 3.8 4 0 0 4 4 4 0 Septum formation initiator Integrase_H2C2 PF17921.1 GBG84889.1 - 2.8e-13 49.7 0.1 7.1e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG84889.1 - 0.0015 19.1 0.0 0.0051 17.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84889.1 - 0.0037 17.9 0.1 0.012 16.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease rve PF00665.26 GBG84889.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 GBG84889.1 - 0.084 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Oxysterol_BP PF01237.18 GBG84889.1 - 7.4 5.3 6.6 12 4.6 6.6 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein RT_RNaseH_2 PF17919.1 GBG84890.1 - 1e-20 73.6 0.0 1.8e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84890.1 - 1.3e-20 73.6 0.0 2.5e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84890.1 - 0.056 12.9 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_carr PF00153.27 GBG84891.1 - 1.8e-51 172.0 1.9 4.9e-17 61.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF563 PF04577.14 GBG84892.1 - 4.8e-19 69.3 0.0 1.6e-09 38.2 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF563) LAM_C PF12544.8 GBG84892.1 - 0.17 12.0 2.3 0.93 9.7 2.0 2.4 2 1 1 3 3 3 0 Lysine-2,3-aminomutase DUF563 PF04577.14 GBG84893.1 - 4.4e-19 69.4 0.0 1.6e-09 38.3 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF563) LAM_C PF12544.8 GBG84893.1 - 0.17 12.1 2.3 0.9 9.7 2.0 2.4 2 1 1 3 3 3 0 Lysine-2,3-aminomutase p450 PF00067.22 GBG84894.1 - 1.6e-33 116.1 0.0 2.2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Asp-B-Hydro_N PF05279.11 GBG84895.1 - 1.5 8.9 35.1 1.9 8.5 35.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 GBG84895.1 - 2.7 6.7 22.9 3.9 6.1 22.9 1.2 1 0 0 1 1 1 0 Presenilin CRT10 PF08728.10 GBG84895.1 - 3.3 5.8 12.9 4 5.5 12.9 1.0 1 0 0 1 1 1 0 CRT10 EFTUD2 PF16004.5 GBG84895.1 - 4.4 7.9 29.7 0.075 13.6 9.8 2.3 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Plavaka PF18759.1 GBG84897.1 - 2.1e-22 79.8 0.5 4.1e-22 78.8 0.5 1.4 1 0 0 1 1 1 1 Plavaka transposase Peptidase_C48 PF02902.19 GBG84897.1 - 0.00029 20.7 1.2 0.0009 19.1 1.2 1.9 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_transf_29 PF00777.18 GBG84898.1 - 9.4e-41 140.0 0.0 1.8e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) RT_RNaseH_2 PF17919.1 GBG84898.1 - 1.3e-25 89.3 0.0 3.4e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84898.1 - 2.1e-23 82.6 0.0 4.4e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84898.1 - 7.2e-13 48.4 0.6 7.2e-13 48.4 0.6 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG84898.1 - 0.00012 22.3 0.5 0.078 13.3 0.0 3.2 2 0 0 2 2 2 2 Retrotransposon gag protein TFIIF_alpha PF05793.12 GBG84898.1 - 4.8 5.7 36.0 0.24 9.9 0.5 3.4 3 0 0 3 3 3 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RVT_1 PF00078.27 GBG84899.1 - 3.3e-26 92.2 0.0 4.8e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84899.1 - 0.0079 16.8 0.0 0.032 14.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH PF17917.1 GBG84900.1 - 2.9e-22 79.0 0.0 6.1e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84900.1 - 5.3e-21 74.5 0.0 1.1e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84900.1 - 1.9e-09 37.4 0.0 3.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG84900.1 - 0.046 14.4 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG84900.1 - 0.046 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Presenilin PF01080.17 GBG84900.1 - 1.5 7.5 3.8 2.6 6.7 3.8 1.3 1 0 0 1 1 1 0 Presenilin RVP_2 PF08284.11 GBG84901.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease CCD48 PF15799.5 GBG84901.1 - 0.0026 16.2 2.7 0.0049 15.3 2.7 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 Asp_protease PF09668.10 GBG84901.1 - 0.032 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG84901.1 - 0.054 14.1 0.0 0.18 12.4 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CCDC85 PF10226.9 GBG84901.1 - 0.07 12.8 0.3 0.16 11.6 0.3 1.6 1 0 0 1 1 1 0 CCDC85 family GvpL_GvpF PF06386.11 GBG84901.1 - 0.08 12.9 7.3 0.15 12.0 7.3 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF848 PF05852.11 GBG84901.1 - 0.13 12.4 2.2 0.19 11.8 1.3 1.6 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) bZIP_1 PF00170.21 GBG84901.1 - 0.19 11.8 0.9 0.45 10.7 0.9 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 GBG84901.1 - 0.92 9.6 6.9 0.15 12.2 2.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Glyco_transf_10 PF00852.19 GBG84902.1 - 6e-28 97.7 0.0 1e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_trans_1_2 PF13524.6 GBG84902.1 - 0.0029 18.0 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Exostosin PF03016.15 GBG84902.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Exostosin family RT_RNaseH_2 PF17919.1 GBG84905.1 - 3.3e-32 110.5 0.1 6.4e-32 109.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84905.1 - 3.6e-28 97.9 0.1 7.2e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84905.1 - 1e-13 51.1 0.0 2.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG84905.1 - 1.8e-10 40.7 0.0 3.7e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG84905.1 - 6.3e-09 36.0 0.1 1.8e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Exonuc_VII_L PF02601.15 GBG84906.1 - 0.24 10.9 3.0 0.41 10.2 3.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sugarporin_N PF11471.8 GBG84906.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.8 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension Snapin_Pallidin PF14712.6 GBG84906.1 - 2.6 8.5 12.5 3.5 8.1 0.4 2.8 1 1 2 3 3 3 0 Snapin/Pallidin CAP_N PF01213.19 GBG84906.1 - 6.7 6.1 9.4 9 5.7 1.5 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal 2OG-FeII_Oxy_2 PF13532.6 GBG84907.1 - 0.057 13.6 0.1 0.2 11.8 0.2 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily RVT_1 PF00078.27 GBG84907.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FA_hydroxylase PF04116.13 GBG84908.1 - 1e-27 97.1 16.2 1.3e-27 96.7 13.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1264 PF06884.11 GBG84909.1 - 2e-72 242.3 0.1 3.2e-72 241.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) RT_RNaseH_2 PF17919.1 GBG84909.1 - 8.1e-30 102.8 0.0 1.6e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84909.1 - 7.4e-28 96.9 0.0 1.4e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84909.1 - 9e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG84909.1 - 0.17 11.3 14.0 0.26 10.7 14.0 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG84909.1 - 0.29 9.4 8.5 0.39 8.9 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG84909.1 - 0.52 8.5 17.1 0.76 7.9 17.1 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 GBG84909.1 - 1.3 7.4 7.0 1.9 6.9 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.16 GBG84909.1 - 1.5 8.0 7.4 2.3 7.4 7.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MAS20 PF02064.15 GBG84909.1 - 1.6 8.8 7.1 3.8 7.6 7.1 1.7 1 0 0 1 1 1 0 MAS20 protein import receptor Paf1 PF03985.13 GBG84909.1 - 3.1 6.7 20.2 4.6 6.1 20.2 1.1 1 0 0 1 1 1 0 Paf1 DUF4746 PF15928.5 GBG84909.1 - 3.3 7.0 14.1 5.2 6.4 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 GBG84909.1 - 4.2 7.1 8.4 6.9 6.4 8.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CPSF100_C PF13299.6 GBG84909.1 - 7.2 6.8 7.9 12 6.1 7.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 GBG84909.1 - 7.6 5.2 6.0 10 4.7 6.0 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG84911.1 - 0.48 8.6 9.3 0.49 8.6 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG84911.1 - 0.69 8.1 9.8 0.86 7.8 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG84911.1 - 0.78 9.0 17.1 1 8.6 17.1 1.2 1 0 0 1 1 1 0 BUD22 RVT_1 PF00078.27 GBG84913.1 - 1.8e-34 119.2 0.1 2.9e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84913.1 - 8.5e-28 96.7 0.0 3.6e-27 94.7 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84913.1 - 4.2e-26 90.9 0.0 2.2e-25 88.6 0.0 2.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rhamno_transf PF11316.8 GBG84913.1 - 0.034 13.5 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative rhamnosyl transferase DUF3138 PF11336.8 GBG84913.1 - 2 6.9 4.4 3.3 6.2 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RVT_1 PF00078.27 GBG84914.1 - 6.7e-20 71.6 0.1 1.1e-19 70.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG84914.1 - 0.55 9.6 20.6 0.75 9.2 20.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG84914.1 - 1.7 6.9 18.9 2.6 6.2 18.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG84914.1 - 2.7 6.1 24.0 3.7 5.6 24.0 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG84914.1 - 8.5 5.6 28.0 12 5.1 28.0 1.1 1 0 0 1 1 1 0 BUD22 ACBP PF00887.19 GBG84915.1 - 1.3e-23 82.9 0.0 2.9e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 GBG84915.1 - 8.1e-19 67.4 0.0 4.4e-15 55.6 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GBG84915.1 - 5e-18 65.2 0.2 3.5e-12 46.6 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GBG84915.1 - 1.1e-15 58.0 0.0 1.9e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GBG84915.1 - 8e-14 51.4 0.0 1.3e-07 31.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 GBG84915.1 - 7.8e-13 47.4 0.1 0.00011 22.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Sigma70_ner PF04546.13 GBG84915.1 - 0.00026 20.9 7.2 0.00026 20.9 7.2 1.7 2 0 0 2 2 2 1 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 GBG84915.1 - 0.0033 17.2 16.7 0.0058 16.4 16.7 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GBG84915.1 - 0.0034 16.8 19.9 0.0056 16.0 19.9 1.3 1 0 0 1 1 1 1 NOA36 protein Nop14 PF04147.12 GBG84915.1 - 0.064 11.5 19.8 0.078 11.2 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG84915.1 - 0.24 9.7 16.3 0.35 9.1 16.3 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 GBG84915.1 - 0.4 10.2 15.3 0.68 9.5 15.3 1.4 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 GBG84915.1 - 1.4 8.8 22.8 2.2 8.2 22.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Drc1-Sld2 PF11719.8 GBG84915.1 - 8.9 5.7 10.2 14 5.1 10.2 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein RT_RNaseH_2 PF17919.1 GBG84916.1 - 2.3e-33 114.2 0.0 6.6e-33 112.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84916.1 - 5.8e-30 103.7 0.1 5.8e-29 100.5 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84916.1 - 3.4e-26 92.2 0.1 5.7e-26 91.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG84916.1 - 7e-17 61.3 0.3 2.1e-16 59.8 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG84916.1 - 2e-08 34.5 0.1 9.7e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain EzrA PF06160.12 GBG84916.1 - 0.027 12.7 1.3 0.049 11.8 1.3 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Retrotrans_gag PF03732.17 GBG84916.1 - 0.042 14.1 0.0 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG84918.1 - 6.1e-50 167.9 1.4 1.1e-28 99.6 0.1 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84918.1 - 1e-48 163.4 1.1 1.9e-35 120.9 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84918.1 - 1.7e-19 69.7 0.6 4.4e-19 68.3 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG84918.1 - 1.9e-13 50.6 0.0 1.4e-12 47.8 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG84918.1 - 7.9e-11 41.9 0.8 1.8e-10 40.7 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG84918.1 - 0.00025 21.2 0.0 0.00086 19.5 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Dapper PF15268.6 GBG84918.1 - 8.2 5.1 68.5 0.54 9.0 62.8 1.8 2 0 0 2 2 2 0 Dapper RT_RNaseH PF17917.1 GBG84919.1 - 4.4e-28 97.6 0.0 1.1e-27 96.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84919.1 - 2.2e-24 85.4 0.0 5.4e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84919.1 - 6.6e-12 45.4 0.0 1.9e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC_3 PF13917.6 GBG84919.1 - 0.09 12.8 4.0 0.22 11.5 4.0 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG84920.1 - 0.0022 18.0 4.0 0.0035 17.3 4.0 1.3 1 0 0 1 1 1 1 Zinc knuckle TolA_bind_tri PF16331.5 GBG84920.1 - 0.01 15.9 4.5 1.1 9.4 3.1 3.4 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF3682 PF12446.8 GBG84920.1 - 0.042 14.3 1.2 0.091 13.2 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) FeoA PF04023.14 GBG84920.1 - 0.063 13.5 0.2 0.21 11.9 0.2 1.9 1 1 0 1 1 1 0 FeoA domain SID-1_RNA_chan PF13965.6 GBG84922.1 - 7.7e-06 24.6 0.0 1.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 CBP_BcsG PF11658.8 GBG84922.1 - 0.0039 15.6 1.2 0.01 14.3 1.2 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsG BUD22 PF09073.10 GBG84922.1 - 0.0072 15.7 58.9 0.0087 15.5 58.9 1.0 1 0 0 1 1 1 1 BUD22 Spore_coat_CotO PF14153.6 GBG84922.1 - 0.018 15.0 32.8 0.03 14.3 32.8 1.5 1 1 0 1 1 1 0 Spore coat protein CotO BAF1_ABF1 PF04684.13 GBG84922.1 - 0.065 12.3 23.6 0.071 12.2 23.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF262 PF03235.14 GBG84922.1 - 0.096 12.8 7.2 0.13 12.5 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 SARAF PF06682.12 GBG84922.1 - 0.2 11.3 12.6 0.38 10.4 12.6 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis GPCR_chapero_1 PF11904.8 GBG84922.1 - 0.25 10.7 12.3 0.27 10.6 12.3 1.2 1 0 0 1 1 1 0 GPCR-chaperone CCSAP PF15748.5 GBG84922.1 - 1.1 9.4 35.7 1.4 9.1 35.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Drc1-Sld2 PF11719.8 GBG84922.1 - 6.2 6.2 38.8 10 5.5 38.8 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein RT_RNaseH_2 PF17919.1 GBG84923.1 - 2.2e-56 188.0 0.0 2.2e-22 79.0 0.0 4.2 4 0 0 4 4 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84923.1 - 2.6e-45 154.6 4.8 2.6e-28 99.0 0.1 5.3 4 1 1 5 5 5 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84923.1 - 1.3e-31 109.0 0.0 4e-15 56.0 0.0 4.0 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase Nuf2 PF03800.14 GBG84923.1 - 1.6e-21 76.9 0.1 4.5e-21 75.4 0.1 1.8 1 0 0 1 1 1 1 Nuf2 family Asp_protease_2 PF13650.6 GBG84923.1 - 1.6e-15 57.5 0.0 3.6e-07 30.7 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG84923.1 - 5.3e-14 52.2 0.0 1.1e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG84923.1 - 4.4e-11 43.2 0.0 5.3e-05 23.7 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG84923.1 - 5.8e-10 39.4 0.0 3.2e-06 27.3 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain Asp_protease PF09668.10 GBG84923.1 - 5.5e-05 23.0 0.0 0.031 14.1 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease DUF1758 PF05585.12 GBG84923.1 - 0.00013 21.7 0.0 0.0041 16.9 0.0 2.3 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Retrotrans_gag PF03732.17 GBG84923.1 - 0.0046 17.2 0.2 0.086 13.1 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein RVP PF00077.20 GBG84923.1 - 0.17 12.2 0.0 14 6.0 0.0 2.8 2 0 0 2 2 2 0 Retroviral aspartyl protease B3 PF02362.21 GBG84924.1 - 0.11 12.4 1.6 0.83 9.6 0.0 2.6 3 0 0 3 3 3 0 B3 DNA binding domain RVT_1 PF00078.27 GBG84925.1 - 4.1e-08 33.0 0.0 9.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG84925.1 - 0.00066 19.5 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG84925.1 - 0.0056 16.9 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein SlyX PF04102.12 GBG84925.1 - 0.84 10.3 2.7 0.78 10.4 0.2 2.1 1 1 1 2 2 2 0 SlyX RVT_1 PF00078.27 GBG84926.1 - 5.8e-26 91.4 0.1 2.6e-24 86.0 0.1 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84926.1 - 7.7e-17 61.2 0.0 3.7e-13 49.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG84926.1 - 1.4e-15 56.9 0.1 2e-10 40.4 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 GBG84926.1 - 1.1e-06 29.1 0.0 0.011 16.2 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG84926.1 - 1.1e-06 28.8 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG84926.1 - 2.8e-05 24.7 0.0 0.081 13.6 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease Asp_protease PF09668.10 GBG84926.1 - 0.0021 17.8 0.5 1.8 8.4 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease rve PF00665.26 GBG84926.1 - 0.0049 17.0 0.1 0.026 14.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain DUF1564 PF07600.11 GBG84926.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Use1 PF09753.9 GBG84926.1 - 0.24 11.1 7.4 0.77 9.4 7.4 1.8 1 0 0 1 1 1 0 Membrane fusion protein Use1 Flot PF15975.5 GBG84926.1 - 2.9 8.1 9.4 7 6.9 9.4 1.6 1 0 0 1 1 1 0 Flotillin DIRP PF06584.13 GBG84927.1 - 0.13 12.4 2.9 0.23 11.7 2.9 1.3 1 0 0 1 1 1 0 DIRP RVT_1 PF00078.27 GBG84928.1 - 4.5e-30 104.8 0.1 6.9e-30 104.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84928.1 - 7.2e-27 93.4 0.0 1.7e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84928.1 - 1.6e-24 86.2 0.0 3.4e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CHASE6_C PF17150.4 GBG84928.1 - 0.097 13.3 0.2 2.9 8.6 0.2 2.3 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain Cnd3 PF12719.7 GBG84929.1 - 1.2e-41 142.8 0.0 2.9e-41 141.6 0.0 1.7 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 GBG84929.1 - 2.9e-06 27.6 6.2 0.057 13.8 0.5 4.1 3 0 0 3 3 3 3 HEAT repeats Asp_protease_2 PF13650.6 GBG84929.1 - 4.9e-06 27.1 0.1 4e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84929.1 - 6.1e-05 23.5 0.0 0.00022 21.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Cnd1 PF12717.7 GBG84929.1 - 0.0001 22.4 0.5 0.38 10.8 0.1 2.6 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GBG84929.1 - 0.00099 19.2 6.7 5.3 7.6 0.2 5.5 5 0 0 5 5 5 2 HEAT repeat RVP_2 PF08284.11 GBG84929.1 - 0.0047 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84929.1 - 0.0055 16.5 0.0 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG84929.1 - 0.024 14.9 0.0 0.077 13.3 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein CDC45 PF02724.14 GBG84933.1 - 0.0033 15.8 18.6 0.0033 15.8 18.6 3.1 3 0 0 3 3 3 1 CDC45-like protein Sigma70_ner PF04546.13 GBG84933.1 - 0.12 12.3 10.7 0.32 10.9 10.7 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region Apt1 PF10351.9 GBG84933.1 - 2 7.2 4.0 1.9 7.3 0.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain YL1 PF05764.13 GBG84933.1 - 2.7 8.0 48.3 0.18 11.9 20.1 3.3 3 0 0 3 3 3 0 YL1 nuclear protein RT_RNaseH_2 PF17919.1 GBG84934.1 - 2e-19 69.5 0.0 4.6e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84934.1 - 6.6e-18 64.9 0.0 2.1e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG84934.1 - 0.00095 19.1 11.0 0.18 12.0 1.9 2.5 2 0 0 2 2 2 2 Zinc knuckle HemN_C PF06969.16 GBG84934.1 - 0.012 15.7 0.0 5.2 7.2 0.0 2.6 2 0 0 2 2 2 0 HemN C-terminal domain ATE_N PF04376.13 GBG84934.1 - 0.14 12.6 1.2 2 8.9 0.0 3.1 3 0 0 3 3 3 0 Arginine-tRNA-protein transferase, N terminus KorB_C PF06613.11 GBG84935.1 - 0.29 11.1 3.0 6.5 6.8 0.3 3.2 3 0 0 3 3 3 0 KorB C-terminal beta-barrel domain DDE_Tnp_4 PF13359.6 GBG84937.1 - 2.1e-32 112.0 0.0 4.9e-32 110.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84937.1 - 7.1e-16 58.4 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG84937.1 - 3.6e-05 23.5 0.3 0.053 13.1 0.0 2.6 2 1 0 2 2 2 2 Transposase DDE domain Nuc_sug_transp PF04142.15 GBG84940.1 - 3.8e-30 105.1 14.5 4.7e-30 104.8 14.5 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 GBG84940.1 - 6.2e-06 25.6 17.4 0.00081 18.7 16.8 2.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 GBG84940.1 - 0.007 16.5 16.9 0.011 15.9 8.3 2.7 2 2 0 2 2 2 2 EamA-like transporter family Phi_1 PF04674.12 GBG84941.1 - 6.5e-24 84.7 0.1 3.3e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 Phosphate-induced protein 1 conserved region tRNA_lig_CPD PF08302.11 GBG84943.1 - 0.0046 16.4 4.9 0.69 9.3 0.1 3.0 2 1 1 3 3 3 2 Fungal tRNA ligase phosphodiesterase domain Spt20 PF12090.8 GBG84943.1 - 2.3 7.8 10.2 4.5 6.8 10.2 1.4 1 0 0 1 1 1 0 Spt20 family Vac7 PF12751.7 GBG84943.1 - 5.1 6.4 9.1 0.32 10.4 3.7 1.6 1 1 1 2 2 2 0 Vacuolar segregation subunit 7 DUF3089 PF11288.8 GBG84944.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Pkinase_Tyr PF07714.17 GBG84946.1 - 1.7e-32 112.7 0.0 1.3e-31 109.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG84946.1 - 2.4e-32 112.3 0.0 2.5e-30 105.7 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG84946.1 - 0.0085 16.0 0.2 0.0085 16.0 0.2 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Ctr PF04145.15 GBG84946.1 - 0.15 12.7 3.2 14 6.3 4.2 2.6 2 0 0 2 2 2 0 Ctr copper transporter family Pkinase_fungal PF17667.1 GBG84946.1 - 0.21 10.3 0.0 0.21 10.3 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase eIF-3_zeta PF05091.12 GBG84946.1 - 0.83 8.6 18.1 1.3 7.9 18.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 GBG84946.1 - 1.9 7.2 8.6 2.9 6.6 8.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 GBG84946.1 - 5.6 5.6 17.4 9.1 4.9 17.4 1.2 1 0 0 1 1 1 0 Presenilin PDDEXK_6 PF04720.12 GBG84946.1 - 8.9 6.2 9.8 15 5.4 9.8 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Tox-GHH PF15636.6 GBG84947.1 - 0.051 13.6 0.8 0.12 12.4 0.8 1.6 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DNA_pol_phi PF04931.13 GBG84947.1 - 2.8 5.9 3.3 4.2 5.3 3.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF659 PF04937.15 GBG84949.1 - 1.2e-30 106.4 0.3 2e-30 105.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PyrI_C PF02748.15 GBG84949.1 - 0.13 12.2 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CCHC PF00098.23 GBG84950.1 - 7.1e-05 22.7 2.1 7.1e-05 22.7 2.1 1.9 2 0 0 2 2 2 1 Zinc knuckle eIF3_p135 PF12807.7 GBG84950.1 - 0.043 13.8 0.4 8.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 zf-CCHC_4 PF14392.6 GBG84950.1 - 0.21 11.4 0.8 0.56 10.0 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle LMBR1 PF04791.16 GBG84950.1 - 1.5 7.6 4.0 1.7 7.4 4.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-CCHC_2 PF13696.6 GBG84950.1 - 1.9 8.4 5.1 1.3 9.0 2.1 2.1 2 0 0 2 2 2 0 Zinc knuckle V_ATPase_I PF01496.19 GBG84950.1 - 4.4 5.1 9.6 5.6 4.8 9.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myb_DNA-bind_4 PF13837.6 GBG84951.1 - 1.4e-06 28.6 4.7 2e-05 24.9 2.4 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain LapA_dom PF06305.11 GBG84951.1 - 0.016 15.0 0.2 0.029 14.2 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MAP17 PF15807.5 GBG84951.1 - 2.1 8.6 3.8 0.59 10.4 0.1 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Co_AT_N PF12557.8 GBG84953.1 - 1.5 8.8 12.1 0.035 14.0 4.7 2.2 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal Dimer_Tnp_hAT PF05699.14 GBG84955.1 - 6.6e-07 29.0 0.2 1.3e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Thioredox_DsbH PF03190.15 GBG84956.1 - 1.4e-69 233.2 0.2 9.2e-37 126.5 0.7 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF255 RT_RNaseH_2 PF17919.1 GBG84956.1 - 1.8e-25 88.9 0.0 4.4e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84956.1 - 2.5e-25 89.3 0.1 4.6e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84956.1 - 1.5e-23 83.1 0.0 3.5e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84956.1 - 2.6e-16 59.5 0.5 1e-15 57.5 0.5 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain Thioredoxin_7 PF13899.6 GBG84956.1 - 7.7e-08 32.4 1.5 1.4e-07 31.6 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like Asp_protease_2 PF13650.6 GBG84956.1 - 4.4e-07 30.4 0.0 1.1e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84956.1 - 7e-06 26.5 0.0 1.6e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84956.1 - 3.4e-05 23.6 0.0 7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG84956.1 - 0.00097 19.4 0.4 0.12 12.7 0.0 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG84956.1 - 0.0014 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG84956.1 - 0.11 12.7 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF3006 PF11213.8 GBG84956.1 - 1.2 9.4 5.3 0.25 11.6 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) RRM_1 PF00076.22 GBG84957.1 - 8.8e-07 28.7 0.0 9.2e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG84957.1 - 0.0022 18.0 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif AAA PF00004.29 GBG84958.1 - 5.8e-32 110.9 0.0 9.4e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG84958.1 - 5.3e-08 33.2 0.1 1.5e-06 28.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG84958.1 - 4.5e-07 30.4 0.1 1.7e-06 28.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 GBG84958.1 - 5e-06 27.1 0.0 2.7e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GBG84958.1 - 1.1e-05 25.5 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GBG84958.1 - 4.8e-05 23.5 0.0 8.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 GBG84958.1 - 7e-05 22.9 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GBG84958.1 - 0.0002 21.5 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GBG84958.1 - 0.00024 21.1 0.1 0.0019 18.2 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 GBG84958.1 - 0.00047 19.8 0.1 0.11 12.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 GBG84958.1 - 0.0007 19.4 0.0 0.0022 17.7 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 GBG84958.1 - 0.00098 19.0 0.0 0.0025 17.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 GBG84958.1 - 0.0011 19.0 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 GBG84958.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GBG84958.1 - 0.0017 18.3 0.0 0.57 10.1 0.0 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GBG84958.1 - 0.0021 18.3 0.0 0.0059 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GBG84958.1 - 0.0022 18.4 0.0 0.0047 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Cytidylate_kin PF02224.18 GBG84958.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.7 1 1 0 1 1 1 1 Cytidylate kinase AAA_7 PF12775.7 GBG84958.1 - 0.0025 17.4 0.0 0.017 14.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 GBG84958.1 - 0.0025 17.6 0.0 0.008 15.9 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein TIP49 PF06068.13 GBG84958.1 - 0.0029 16.8 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 GBG84958.1 - 0.0032 16.7 0.0 0.011 15.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) Rad17 PF03215.15 GBG84958.1 - 0.0062 16.5 0.0 0.017 15.0 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 GBG84958.1 - 0.0069 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 GBG84958.1 - 0.0081 16.0 0.0 0.024 14.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 GBG84958.1 - 0.0096 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 GBG84958.1 - 0.012 15.4 0.0 0.038 13.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 GBG84958.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 GBG84958.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 GBG84958.1 - 0.015 15.6 0.1 0.093 13.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 GBG84958.1 - 0.043 13.3 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 GBG84958.1 - 0.049 12.9 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 GBG84958.1 - 0.054 14.0 0.0 0.095 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 GBG84958.1 - 0.065 13.3 0.0 0.22 11.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 GBG84958.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DnaB_C PF03796.15 GBG84958.1 - 0.071 12.4 0.0 0.19 11.1 0.0 1.6 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 GBG84958.1 - 0.072 12.7 0.3 1.1 8.9 0.0 2.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 GBG84958.1 - 0.075 11.7 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GBG84958.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Vta1_C PF18097.1 GBG84958.1 - 0.11 12.2 0.1 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Vta1 C-terminal domain ATPase PF06745.13 GBG84958.1 - 0.12 11.7 0.1 0.8 9.0 0.0 2.0 1 1 1 2 2 2 0 KaiC MORN_2 PF07661.13 GBG84958.1 - 0.16 12.2 0.1 0.46 10.9 0.1 1.8 1 0 0 1 1 1 0 MORN repeat variant DUF3774 PF12609.8 GBG84959.1 - 0.1 13.6 0.7 0.31 12.1 0.7 1.9 1 1 0 1 1 1 0 Wound-induced protein SRP-alpha_N PF04086.13 GBG84960.1 - 0.0015 18.5 2.6 0.0027 17.7 2.6 1.5 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Retrotrans_gag PF03732.17 GBG84960.1 - 0.011 16.0 0.1 0.029 14.7 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG84960.1 - 0.11 12.4 2.4 0.19 11.7 2.4 1.3 1 0 0 1 1 1 0 Zinc knuckle TraD PF06412.11 GBG84960.1 - 0.31 10.9 2.2 11 5.9 0.0 2.8 3 0 0 3 3 3 0 Conjugal transfer protein TraD Proteasome PF00227.26 GBG84961.1 - 1.3e-61 207.4 0.1 1.6e-61 207.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GBG84961.1 - 7.1e-14 51.2 0.1 1.3e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DCA16 PF15349.6 GBG84961.1 - 0.013 15.0 0.0 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 DDB1- and CUL4-associated factor 16 RT_RNaseH_2 PF17919.1 GBG84962.1 - 2.5e-29 101.3 0.0 5.7e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84962.1 - 1.5e-28 99.9 0.0 2.7e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84962.1 - 5.1e-26 91.0 0.0 1e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG84962.1 - 2.4e-18 66.4 0.0 5.2e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG84962.1 - 2.8e-14 53.0 0.1 9.3e-14 51.3 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG84962.1 - 0.00088 19.4 0.0 0.003 17.7 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger tRNA_lig_CPD PF08302.11 GBG84962.1 - 0.027 13.9 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Integrase_H2C2 PF17921.1 GBG84963.1 - 1.5e-16 60.3 1.0 1.3e-15 57.2 0.0 3.0 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG84963.1 - 1.9e-12 47.4 0.1 5.9e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG84963.1 - 4.7e-06 26.7 0.0 2.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger DEC-1_N PF04625.13 GBG84965.1 - 0.66 8.9 7.1 0.13 11.2 2.8 1.9 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DUF572 PF04502.13 GBG84965.1 - 5.8 6.4 16.3 3.8 7.0 2.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) RVT_1 PF00078.27 GBG84966.1 - 3.2e-27 95.5 0.1 5.2e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84966.1 - 3.9e-08 33.2 0.0 9.2e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG84967.1 - 1.4e-15 57.1 0.0 4.6e-15 55.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84967.1 - 1.7e-11 44.0 0.2 4.5e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84967.1 - 6.2e-07 29.7 0.0 2.5e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG84967.1 - 5.6e-05 23.3 2.9 0.0024 18.1 0.2 4.2 4 0 0 4 4 4 1 Retrotransposon gag protein FAM76 PF16046.5 GBG84967.1 - 0.056 12.8 8.8 0.11 11.8 8.8 1.4 1 0 0 1 1 1 0 FAM76 protein DUF4187 PF13821.6 GBG84967.1 - 0.085 12.7 5.3 0.039 13.8 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) UPF0242 PF06785.11 GBG84967.1 - 4 7.5 20.8 2.7e+02 1.5 20.8 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Dimer_Tnp_hAT PF05699.14 GBG84968.1 - 1.9e-09 37.2 0.1 3.7e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region VRR_NUC PF08774.11 GBG84969.1 - 2.6e-26 91.8 0.0 1.9e-25 89.0 0.0 2.0 1 1 0 1 1 1 1 VRR-NUC domain Exo70 PF03081.15 GBG84970.1 - 4.2e-104 348.6 0.5 4.3e-103 345.3 0.1 2.1 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Sec34 PF04136.15 GBG84970.1 - 0.00034 20.5 0.1 0.00097 19.0 0.1 1.8 1 0 0 1 1 1 1 Sec34-like family Sec3_C PF09763.9 GBG84970.1 - 0.025 13.0 0.5 0.2 10.0 0.1 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec3 Myb_DNA-bind_3 PF12776.7 GBG84970.1 - 0.16 13.0 0.9 0.84 10.7 0.3 2.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Beta_helix PF13229.6 GBG84972.1 - 2.2e-07 30.8 0.3 0.00011 22.1 0.1 2.2 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 GBG84972.1 - 0.029 13.6 0.2 0.34 10.2 0.2 1.9 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Retrotrans_gag PF03732.17 GBG84974.1 - 0.00099 19.3 0.9 0.0044 17.3 0.4 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein DUF4539 PF15072.6 GBG84974.1 - 0.0024 17.9 6.9 0.27 11.3 1.2 3.3 1 1 2 3 3 3 2 Domain of unknown function (DUF4539) RHH_7 PF16777.5 GBG84974.1 - 0.11 12.9 0.6 0.29 11.5 0.6 1.7 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG Bet_v_1 PF00407.19 GBG84974.1 - 0.57 10.1 9.9 0.15 12.0 3.1 2.4 2 0 0 2 2 2 0 Pathogenesis-related protein Bet v I family RT_RNaseH_2 PF17919.1 GBG84975.1 - 3.1e-20 72.1 0.0 6e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG84975.1 - 2.6e-11 43.5 0.1 3.9e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG84975.1 - 1.9e-09 37.8 0.0 3.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Beta_helix PF13229.6 GBG84975.1 - 9.2e-06 25.6 0.8 2e-05 24.5 0.7 1.6 2 0 0 2 2 2 1 Right handed beta helix region Beta_helix PF13229.6 GBG84977.1 - 9.9e-07 28.7 1.1 3.4e-06 27.0 1.5 1.7 1 1 1 2 2 2 2 Right handed beta helix region DUF659 PF04937.15 GBG84979.1 - 3.3e-12 46.5 0.0 6.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Beta_helix PF13229.6 GBG84981.1 - 4.1e-08 33.2 1.0 2.7e-07 30.6 1.4 1.9 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 GBG84981.1 - 0.19 11.0 0.2 0.24 10.7 0.2 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) SH3-RhoG_link PF16609.5 GBG84982.1 - 0.16 11.7 2.4 0.27 10.9 2.4 1.3 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region Beta_helix PF13229.6 GBG84983.1 - 1.1e-06 28.6 3.9 2.3e-06 27.6 4.0 1.5 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG84983.1 - 0.17 11.1 0.3 0.22 10.8 0.3 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DDE_Tnp_4 PF13359.6 GBG84984.1 - 1.8e-06 27.7 0.0 7.2e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG84984.1 - 0.0076 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG84985.1 - 0.00017 21.9 0.2 0.0017 18.7 0.1 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 GBG84986.1 - 1.1e-72 244.5 0.1 1.4e-72 244.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG84986.1 - 1.5e-39 135.9 0.2 2e-39 135.4 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG84986.1 - 3.9e-09 36.3 0.1 2.7e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_C PF00433.24 GBG84986.1 - 5.1e-05 23.9 0.0 0.00013 22.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 GBG84986.1 - 6e-05 22.0 0.1 0.00012 21.0 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GBG84986.1 - 0.00019 20.5 0.1 0.00029 19.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GBG84986.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GBG84986.1 - 0.0059 15.7 0.1 0.009 15.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 GBG84986.1 - 0.0098 15.3 0.2 0.018 14.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GBG84986.1 - 0.061 12.9 2.3 0.16 11.5 0.1 2.1 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 GBG84986.1 - 0.18 11.4 0.5 21 4.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4407 PF14362.6 GBG84987.1 - 0.088 12.1 5.3 0.099 12.0 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ThiF PF00899.21 GBG84988.1 - 4.5e-85 284.9 0.0 1.8e-54 184.7 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GBG84988.1 - 2.1e-78 263.7 0.0 5e-78 262.5 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 GBG84988.1 - 5.8e-27 94.2 0.0 1.1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 GBG84988.1 - 1.1e-20 73.6 0.1 2.1e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 GBG84988.1 - 1.4e-08 34.8 0.0 3.7e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle 2-Hacid_dh_C PF02826.19 GBG84988.1 - 0.13 11.6 1.0 12 5.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GBG84988.1 - 0.29 11.2 1.1 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 GBG84988.1 - 4 8.1 7.5 3.9 8.1 1.2 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RT_RNaseH PF17917.1 GBG84991.1 - 7.6e-20 71.2 0.0 4.9e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG84991.1 - 1.5e-16 60.5 0.0 3.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 GBG84991.1 - 4.6e-11 42.6 0.0 1.5e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Plant_tran PF04827.14 GBG84991.1 - 3.2e-07 30.2 0.0 6.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein gag-asp_proteas PF13975.6 GBG84991.1 - 9.7e-07 29.3 0.0 2.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG84991.1 - 1e-06 29.3 1.2 1.3e-06 28.9 0.0 1.9 2 0 0 2 2 1 1 Aspartyl protease RVP_2 PF08284.11 GBG84991.1 - 2.1e-05 24.3 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84991.1 - 0.00028 20.7 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DDE_Tnp_1 PF01609.21 GBG84991.1 - 0.0036 17.0 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain Med20 PF08612.11 GBG84991.1 - 0.083 12.2 0.5 0.16 11.3 0.5 1.4 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex BUD22 PF09073.10 GBG84991.1 - 0.38 10.0 22.9 0.57 9.5 22.9 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GBG84991.1 - 8.1 5.1 5.4 12 4.5 5.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Retrotrans_gag PF03732.17 GBG84992.1 - 7.6e-05 22.9 0.5 0.0016 18.7 0.1 2.8 2 1 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG84993.1 - 2.9e-23 82.6 0.1 4.9e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84993.1 - 2.8e-22 78.6 0.0 5.6e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84993.1 - 6.8e-22 77.7 0.0 1.3e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG84993.1 - 1.8e-17 63.2 0.4 4.2e-17 62.0 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG84993.1 - 0.028 14.6 0.0 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 GBG84993.1 - 0.045 13.5 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Beta_helix PF13229.6 GBG84994.1 - 3.1e-07 30.4 5.1 4.9e-07 29.7 4.7 1.5 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG84994.1 - 0.015 14.5 0.8 0.066 12.5 0.8 1.7 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF5123 PF17161.4 GBG84994.1 - 0.24 12.5 0.7 2.5 9.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5123) Chlam_PMP PF02415.17 GBG84994.1 - 1.7 9.3 18.1 0.12 12.9 2.1 5.4 5 2 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF659 PF04937.15 GBG84995.1 - 9.9e-13 48.2 0.0 8.6e-08 32.2 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) DUF2781 PF10914.8 GBG84996.1 - 0.4 11.1 1.9 0.75 10.2 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2781) RVT_1 PF00078.27 GBG84997.1 - 1.3e-29 103.3 0.2 2e-29 102.7 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG84997.1 - 1.3e-23 82.9 0.0 2.6e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG84997.1 - 1.3e-19 70.4 0.0 2.8e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG84997.1 - 1.9e-06 28.4 0.0 4.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG84997.1 - 1.5e-05 25.4 0.0 3.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG84997.1 - 0.00089 19.0 0.0 0.0022 17.8 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG84997.1 - 0.0053 16.5 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_S74 PF13884.6 GBG84998.1 - 0.0074 16.6 0.3 0.97 9.8 0.0 2.4 2 0 0 2 2 2 2 Chaperone of endosialidase RepB-RCR_reg PF10723.9 GBG84998.1 - 0.011 15.6 0.1 0.028 14.4 0.1 1.7 1 0 0 1 1 1 0 Replication regulatory protein RepB VIGSSK PF14773.6 GBG84998.1 - 0.012 15.8 0.5 0.029 14.5 0.0 1.9 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal Beta_helix PF13229.6 GBG84999.1 - 3.2e-08 33.6 4.6 6.2e-08 32.6 4.3 1.6 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG84999.1 - 0.0032 16.8 0.7 0.0075 15.6 0.7 1.5 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 GBG84999.1 - 0.11 13.0 12.6 0.15 12.6 3.1 4.4 4 2 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat PAP_assoc PF03828.19 GBG85004.1 - 4.9e-11 42.7 0.1 1.2e-09 38.2 0.0 2.5 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GBG85004.1 - 1.4e-09 38.1 0.0 3.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Myb_DNA-bind_4 PF13837.6 GBG85005.1 - 0.00036 20.9 1.7 0.00066 20.0 1.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Beta_helix PF13229.6 GBG85005.1 - 0.00048 20.0 0.0 0.0029 17.5 0.0 2.0 1 1 0 1 1 1 1 Right handed beta helix region 2OG-FeII_Oxy_2 PF13532.6 GBG85005.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RT_RNaseH_2 PF17919.1 GBG85008.1 - 1.1e-27 95.9 0.5 3.8e-27 94.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85008.1 - 8.8e-25 87.0 2.3 9.3e-25 86.9 0.2 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85008.1 - 3.1e-13 50.0 0.1 1.3e-12 48.0 0.1 2.1 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG85008.1 - 0.01 15.8 0.9 0.024 14.6 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG85008.1 - 0.22 11.3 1.4 0.61 9.9 0.8 2.1 2 0 0 2 2 2 0 Zinc knuckle NPV_P10 PF05531.12 GBG85008.1 - 1.5 9.3 14.8 2.8 8.5 1.9 4.2 2 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein zf-CCHC PF00098.23 GBG85008.1 - 2.3 8.5 4.9 4.1 7.6 4.9 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG85009.1 - 4.3e-57 193.2 1.5 2e-28 99.4 0.2 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG85009.1 - 1.2e-15 57.8 0.0 2.8e-06 27.8 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85009.1 - 1.2e-11 45.1 0.0 9.1e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG85009.1 - 2.8e-11 43.3 0.0 1.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85009.1 - 5.6e-11 42.3 0.0 0.00049 19.9 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG85009.1 - 0.0014 18.6 0.0 0.006 16.6 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ZapB PF06005.12 GBG85009.1 - 0.049 14.1 0.1 0.049 14.1 0.1 3.7 3 0 0 3 3 3 0 Cell division protein ZapB Pribosyltran PF00156.27 GBG85009.1 - 0.066 12.7 0.0 16 5.0 0.0 2.6 2 0 0 2 2 2 0 Phosphoribosyl transferase domain NPV_P10 PF05531.12 GBG85009.1 - 8.9 6.9 8.1 34 5.0 1.0 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG85010.1 - 2.6e-30 105.6 0.1 4.3e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG85010.1 - 2.8e-15 56.2 2.6 6.9e-15 54.9 0.0 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG85010.1 - 9.8e-13 48.3 0.0 3.5e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG85010.1 - 0.00014 22.0 0.0 0.00038 20.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Sec6 PF06046.13 GBG85011.1 - 0.27 9.6 8.0 0.42 8.9 8.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec6 DASH_Ask1 PF08655.10 GBG85013.1 - 0.098 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Ask1 Sushi PF00084.20 GBG85013.1 - 0.14 12.7 0.3 0.31 11.7 0.3 1.4 1 0 0 1 1 1 0 Sushi repeat (SCR repeat) G0-G1_switch_2 PF15103.6 GBG85013.1 - 3.7 8.0 8.3 1.5 9.2 5.5 1.8 2 0 0 2 2 2 0 G0/G1 switch protein 2 BUD22 PF09073.10 GBG85016.1 - 0.0043 16.5 15.3 0.0053 16.2 15.3 1.0 1 0 0 1 1 1 1 BUD22 TLP-20 PF06088.11 GBG85016.1 - 0.028 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nop14 PF04147.12 GBG85016.1 - 0.065 11.5 14.9 0.073 11.3 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family CRT10 PF08728.10 GBG85016.1 - 0.17 10.0 0.2 0.18 9.9 0.2 1.0 1 0 0 1 1 1 0 CRT10 DUF4820 PF16091.5 GBG85016.1 - 0.36 10.2 2.7 0.48 9.8 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TRAP_alpha PF03896.16 GBG85016.1 - 0.42 9.8 6.9 0.58 9.3 6.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RR_TM4-6 PF06459.12 GBG85016.1 - 0.82 9.4 10.1 1.3 8.8 10.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG85016.1 - 0.98 8.8 17.5 1.2 8.5 17.5 1.1 1 0 0 1 1 1 0 SDA1 MRNIP PF15749.5 GBG85016.1 - 1.3 9.7 5.0 2.2 9.0 5.0 1.3 1 0 0 1 1 1 0 MRN-interacting protein DNA_pol_phi PF04931.13 GBG85016.1 - 1.6 6.8 15.3 2 6.4 15.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi MAP17 PF15807.5 GBG85016.1 - 1.7 8.9 7.8 2.6 8.3 7.8 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LAP1C PF05609.12 GBG85016.1 - 1.8 7.6 9.1 2.3 7.2 9.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 GBG85016.1 - 2.1 7.0 5.8 2.4 6.9 5.8 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG85016.1 - 2.6 6.3 14.7 3.6 5.8 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein HSP70 PF00012.20 GBG85016.1 - 2.8 6.0 5.9 3.5 5.7 5.9 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF4746 PF15928.5 GBG85016.1 - 6.7 6.0 16.9 9.6 5.5 16.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) YL1 PF05764.13 GBG85016.1 - 8.2 6.5 23.7 11 6.0 23.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein RT_RNaseH_2 PF17919.1 GBG85017.1 - 3.7e-07 30.1 0.0 7.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85017.1 - 1.8e-05 24.9 0.0 4.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG85017.1 - 0.00048 20.6 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85017.1 - 0.0043 17.7 0.0 0.0099 16.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85017.1 - 0.0062 16.8 0.1 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG85017.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG85017.1 - 0.016 15.0 0.1 0.045 13.5 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease Ku_N PF03731.15 GBG85017.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain Pep_deformylase PF01327.21 GBG85018.1 - 0.12 11.9 0.8 0.21 11.2 0.8 1.3 1 0 0 1 1 1 0 Polypeptide deformylase AIF_C PF14721.6 GBG85018.1 - 0.18 12.2 2.7 0.28 11.5 1.3 1.9 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RVT_1 PF00078.27 GBG85019.1 - 0.08 12.4 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF573 PF04504.14 GBG85020.1 - 0.081 13.6 0.2 0.081 13.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Myb_DNA-bind_3 PF12776.7 GBG85020.1 - 0.23 12.5 0.3 0.23 12.5 0.3 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4375 PF14300.6 GBG85020.1 - 7 7.0 8.7 18 5.6 8.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Na_trans_assoc PF06512.13 GBG85021.1 - 0.0053 17.1 19.0 0.008 16.5 19.0 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated TFIIA PF03153.13 GBG85021.1 - 0.25 11.3 21.2 0.32 10.9 21.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 GBG85021.1 - 0.32 9.1 33.7 0.41 8.8 33.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG85021.1 - 0.46 8.7 28.4 0.035 12.4 23.8 1.4 2 0 0 2 2 2 0 CDC45-like protein Connexin PF00029.19 GBG85021.1 - 0.99 9.1 10.8 29 4.3 0.0 2.1 2 0 0 2 2 2 0 Connexin Afi1 PF07792.12 GBG85021.1 - 1.3 9.5 15.6 11 6.4 15.6 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CobT PF06213.12 GBG85021.1 - 1.5 8.2 32.1 0.77 9.1 28.3 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RPN2_C PF18004.1 GBG85021.1 - 1.9 8.4 19.2 1.4 8.8 16.0 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2457 PF10446.9 GBG85021.1 - 6.5 5.8 44.1 11 5.0 38.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 GBG85021.1 - 6.7 5.1 24.8 9.2 4.7 24.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.10 GBG85021.1 - 8.4 6.7 21.5 3.1 8.1 17.5 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SpoIIP PF07454.11 GBG85021.1 - 9 5.7 14.9 1.9 7.9 11.2 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RT_RNaseH_2 PF17919.1 GBG85022.1 - 4.5e-26 90.8 0.0 2.4e-25 88.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85022.1 - 1.5e-20 73.4 0.0 6.2e-20 71.4 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85022.1 - 0.00019 21.0 0.2 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HIP1_clath_bdg PF16515.5 GBG85022.1 - 0.0037 17.8 7.2 0.0037 17.8 7.2 4.4 4 1 0 4 4 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc29 PF17082.5 GBG85022.1 - 0.0093 15.8 2.2 0.11 12.4 0.5 2.5 2 0 0 2 2 2 1 Spindle Pole Component 29 DUF4407 PF14362.6 GBG85022.1 - 0.024 14.0 20.5 0.048 13.0 1.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Retrotrans_gag PF03732.17 GBG85022.1 - 0.037 14.3 8.8 1.1 9.5 0.0 4.5 4 0 0 4 4 4 0 Retrotransposon gag protein DUF4777 PF16007.5 GBG85022.1 - 0.091 13.0 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) FUSC PF04632.12 GBG85022.1 - 0.23 9.9 21.2 0.35 9.3 18.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Snapin_Pallidin PF14712.6 GBG85022.1 - 0.61 10.5 10.5 0.14 12.6 3.0 3.3 3 0 0 3 3 3 0 Snapin/Pallidin USP8_interact PF08941.10 GBG85022.1 - 1.3 8.8 6.4 27 4.5 0.0 3.0 2 1 0 2 2 2 0 USP8 interacting NPV_P10 PF05531.12 GBG85022.1 - 1.5 9.4 9.7 7.4 7.1 0.8 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 GBG85022.1 - 1.5 9.2 13.0 1 9.7 2.9 4.0 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.11 GBG85022.1 - 2.7 8.6 10.4 5.3 7.7 1.5 3.9 2 2 1 3 3 3 0 Syntaxin 6, N-terminal DUF2408 PF10303.9 GBG85022.1 - 3.3 8.3 14.3 16 6.1 8.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) RVT_1 PF00078.27 GBG85023.1 - 5.6e-24 84.9 0.0 9.9e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85023.1 - 8.3e-23 80.3 0.0 1.9e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85023.1 - 2.8e-19 69.4 0.0 5.9e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-binding PF00249.31 GBG85023.1 - 0.0068 16.6 0.0 0.025 14.8 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG85023.1 - 0.011 15.9 0.0 0.041 14.1 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Apolipoprotein PF01442.18 GBG85023.1 - 0.024 14.5 1.3 0.82 9.5 0.0 3.0 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 GBG85023.1 - 0.032 14.2 1.0 4.1 7.4 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 GBG85023.1 - 0.99 8.8 4.2 0.36 10.2 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) zf-HC2 PF13490.6 GBG85023.1 - 1.5 9.2 5.2 0.17 12.2 0.4 1.9 2 0 0 2 2 2 0 Putative zinc-finger SUIM_assoc PF16619.5 GBG85023.1 - 3.1 8.0 8.4 13 6.0 8.4 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 NAD_binding_10 PF13460.6 GBG85025.1 - 5.1e-21 75.4 3.4 5.1e-21 75.4 3.4 2.3 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 GBG85025.1 - 6.1e-10 39.0 1.4 1.5e-09 37.8 1.4 1.6 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GBG85025.1 - 0.0053 16.2 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GBG85025.1 - 0.0054 15.8 0.1 0.0094 15.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GBG85025.1 - 0.019 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF572 PF04502.13 GBG85025.1 - 0.81 9.2 10.1 1.3 8.5 10.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Spore_III_AF PF09581.10 GBG85025.1 - 1.3 9.0 7.7 0.33 10.9 3.6 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) MCU PF04678.13 GBG85025.1 - 6.8 6.7 5.8 17 5.5 5.8 1.7 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Exonuc_VII_L PF02601.15 GBG85027.1 - 0.0056 16.3 1.3 0.0081 15.8 1.3 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit DHR10 PF18595.1 GBG85027.1 - 0.02 15.0 7.5 0.02 15.0 7.5 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Filament PF00038.21 GBG85027.1 - 0.02 14.5 11.7 0.028 14.0 11.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein HMMR_N PF15905.5 GBG85027.1 - 0.13 11.7 10.1 0.19 11.2 10.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal USP8_interact PF08941.10 GBG85027.1 - 0.15 11.9 4.2 8.5 6.2 3.1 2.3 2 0 0 2 2 2 0 USP8 interacting Spc7 PF08317.11 GBG85027.1 - 0.18 10.7 10.4 0.25 10.2 10.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF745 PF05335.13 GBG85027.1 - 0.21 11.3 5.1 0.36 10.5 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Atg14 PF10186.9 GBG85027.1 - 0.3 10.1 6.3 0.48 9.4 6.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 GBG85027.1 - 1.7 8.7 12.8 0.35 10.9 8.6 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EIIBC-GUT_N PF03612.14 GBG85030.1 - 0.09 12.5 0.5 0.12 12.1 0.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Chorein_N PF12624.7 GBG85030.1 - 0.22 11.6 4.8 0.33 11.1 4.8 1.3 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 GIY-YIG PF01541.24 GBG85031.1 - 1.3e-06 28.6 0.0 1.3e-06 28.6 0.0 3.3 3 1 1 4 4 4 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG85031.1 - 0.00016 21.6 2.2 0.00039 20.4 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-Mss51 PF13824.6 GBG85031.1 - 0.019 15.0 0.2 0.081 13.0 0.2 2.1 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Alanine_zipper PF11839.8 GBG85031.1 - 0.029 14.7 18.8 0.073 13.4 18.8 1.6 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Prok-RING_1 PF14446.6 GBG85031.1 - 0.13 12.3 0.6 0.37 10.8 0.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CCHC_2 PF13696.6 GBG85031.1 - 0.6 10.0 3.0 0.34 10.8 1.0 1.6 2 0 0 2 2 2 0 Zinc knuckle UPF0121 PF03661.13 GBG85032.1 - 2.9e-06 26.9 9.8 3.7e-06 26.5 9.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF4187 PF13821.6 GBG85033.1 - 0.031 14.1 2.8 0.11 12.3 2.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG85033.1 - 0.095 12.0 11.0 0.2 11.0 11.0 1.5 1 0 0 1 1 1 0 FAM76 protein YrbL-PhoP_reg PF10707.9 GBG85033.1 - 0.12 11.9 1.1 0.24 10.9 1.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Retrotrans_gag PF03732.17 GBG85033.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.1 4 1 1 5 5 5 0 Retrotransposon gag protein DUF3381 PF11861.8 GBG85033.1 - 2 8.2 11.3 5.4 6.8 11.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF659 PF04937.15 GBG85034.1 - 1.7e-07 31.2 0.0 2.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC_2 PF13696.6 GBG85035.1 - 0.016 15.0 2.4 0.016 15.0 2.4 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG85035.1 - 0.044 13.9 0.9 0.044 13.9 0.9 1.9 2 0 0 2 2 2 0 Zinc knuckle SOBP PF15279.6 GBG85035.1 - 1.2 9.6 5.3 1.8 9.1 5.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Paf1 PF03985.13 GBG85037.1 - 0.089 11.8 7.6 0.1 11.6 7.6 1.1 1 0 0 1 1 1 0 Paf1 bHLH-MYC_N PF14215.6 GBG85037.1 - 0.2 11.9 0.6 0.23 11.7 0.6 1.1 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal CDC45 PF02724.14 GBG85037.1 - 0.23 9.7 5.2 0.26 9.6 5.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GBG85037.1 - 0.97 7.9 3.7 1 7.8 3.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nup54 PF13874.6 GBG85038.1 - 1.3e-27 96.6 5.5 1.3e-27 96.6 5.5 2.8 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 CTD PF12815.7 GBG85038.1 - 7.4e-10 39.3 13.4 3.7e-05 24.2 13.4 3.2 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Nucleoporin_FG PF13634.6 GBG85038.1 - 0.015 16.2 66.6 0.055 14.3 18.9 3.8 1 1 2 3 3 3 0 Nucleoporin FG repeat region Nup54_C PF18437.1 GBG85038.1 - 0.023 14.6 0.8 0.023 14.6 0.8 2.1 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain SNARE_assoc PF09335.11 GBG85039.1 - 2.4e-22 79.6 8.3 2.4e-22 79.6 8.3 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein PRIMA1 PF16101.5 GBG85039.1 - 0.034 14.2 1.5 1.4 8.9 0.1 3.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Plasmodium_Vir PF05795.11 GBG85039.1 - 0.14 11.6 1.4 0.14 11.5 0.2 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF1180 PF06679.12 GBG85039.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Rrn6 PF10214.9 GBG85039.1 - 0.22 10.0 8.6 0.33 9.4 8.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM176 PF14851.6 GBG85039.1 - 0.63 9.7 2.8 26 4.5 0.0 2.8 2 0 0 2 2 2 0 FAM176 family PFK PF00365.20 GBG85040.1 - 1.5e-33 116.4 0.0 1.8e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 GBG85040.1 - 0.056 13.1 0.2 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF4820 PF16091.5 GBG85040.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RVT_1 PF00078.27 GBG85041.1 - 1.8e-18 66.9 0.0 4.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG85041.1 - 5.7e-16 58.4 3.0 6.4e-16 58.2 0.4 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG85041.1 - 9e-16 57.8 0.0 2.2e-14 53.3 0.0 2.5 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85041.1 - 1.9e-15 57.0 0.8 8.3e-08 32.5 0.0 2.9 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85041.1 - 7.8e-11 42.2 0.0 2.6e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DUF4187 PF13821.6 GBG85041.1 - 0.0089 15.8 0.6 0.03 14.1 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG85041.1 - 0.012 15.9 0.1 0.012 15.9 0.1 2.5 3 0 0 3 3 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG85041.1 - 0.018 15.3 0.2 0.042 14.1 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 GBG85041.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG85041.1 - 0.11 13.1 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Macoilin PF09726.9 GBG85041.1 - 0.21 10.1 1.0 0.36 9.3 1.0 1.2 1 0 0 1 1 1 0 Macoilin family Mt_ATP-synt_B PF05405.14 GBG85041.1 - 1.2 8.8 5.9 2.1 7.9 5.9 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ZapB PF06005.12 GBG85041.1 - 3.8 8.0 9.6 15 6.1 9.6 2.1 1 0 0 1 1 1 0 Cell division protein ZapB HXXSHH PF07586.11 GBG85042.1 - 0.095 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Glyco_transf_29 PF00777.18 GBG85043.1 - 3.2e-15 56.3 0.1 5.4e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) EB PF01683.18 GBG85043.1 - 0.049 13.9 4.8 0.13 12.5 4.8 1.7 1 0 0 1 1 1 0 EB module Peptidase_M16_C PF05193.21 GBG85044.1 - 7.4e-40 136.9 0.0 1.1e-19 71.1 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GBG85044.1 - 3.1e-25 88.9 0.7 7.5e-25 87.7 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2407_C PF13373.6 GBG85044.1 - 0.034 14.3 0.5 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 DUF2407 C-terminal domain ACT PF01842.25 GBG85044.1 - 0.034 13.9 0.2 2.9 7.8 0.0 3.1 3 0 0 3 3 3 0 ACT domain WD40 PF00400.32 GBG85048.1 - 2e-24 85.4 6.5 0.0004 21.1 0.0 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat zf_CCCH_4 PF18345.1 GBG85048.1 - 7.5e-11 41.7 18.7 1.3e-06 28.2 1.5 3.3 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 GBG85048.1 - 3.1e-09 36.4 13.3 1.4e-06 28.0 2.3 3.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 GBG85048.1 - 3.9e-09 36.2 8.9 0.00051 19.9 1.0 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GBG85048.1 - 3.4e-07 30.9 3.0 0.0016 19.1 0.1 2.4 2 0 0 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 GBG85048.1 - 0.0003 21.0 0.9 0.071 13.3 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger containing family Nup160 PF11715.8 GBG85048.1 - 0.0019 16.9 1.0 0.69 8.5 0.1 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 zf_CCCH_5 PF18384.1 GBG85048.1 - 0.18 12.0 0.8 0.51 10.5 0.8 1.8 1 0 0 1 1 1 0 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH_2 PF14608.6 GBG85048.1 - 3.3 8.3 19.8 0.34 11.5 1.0 3.6 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger WD40 PF00400.32 GBG85049.1 - 3.1e-23 81.6 8.1 0.00021 22.0 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 GBG85049.1 - 0.0003 19.6 0.9 0.34 9.5 0.1 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 YdjO PF14169.6 GBG85049.1 - 0.11 12.3 0.4 0.38 10.5 0.4 1.9 1 0 0 1 1 1 0 Cold-inducible protein YdjO RNase_T PF00929.24 GBG85051.1 - 3e-08 34.4 0.1 1.6e-07 32.1 0.1 2.1 1 1 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 GBG85051.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like BUD22 PF09073.10 GBG85052.1 - 0.29 10.4 27.9 0.61 9.4 27.9 1.5 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG85052.1 - 1.4 7.0 36.2 2.1 6.5 36.2 1.2 1 0 0 1 1 1 0 Nop14-like family DDE_Tnp_4 PF13359.6 GBG85053.1 - 9.7e-26 90.3 0.0 2.7e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85053.1 - 1.3e-10 41.2 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85053.1 - 0.065 12.9 0.4 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG85056.1 - 9.1e-31 106.7 0.0 1.6e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85056.1 - 3.3e-12 46.5 0.0 5.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85056.1 - 0.044 13.4 0.1 2.4 7.7 0.2 2.3 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG85056.1 - 0.083 13.3 0.2 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain DUF659 PF04937.15 GBG85057.1 - 7.8e-07 29.1 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG85057.1 - 0.0065 16.5 0.8 0.022 14.8 0.8 2.0 1 0 0 1 1 1 1 Zinc knuckle Dimer_Tnp_hAT PF05699.14 GBG85057.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region CemA PF03040.14 GBG85057.1 - 0.2 11.5 2.0 0.48 10.3 2.0 1.5 1 0 0 1 1 1 0 CemA family Myb_DNA-bind_4 PF13837.6 GBG85058.1 - 4.3e-08 33.4 1.4 8.1e-08 32.5 1.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85058.1 - 0.0077 16.5 0.2 0.015 15.6 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG85058.1 - 0.078 13.1 0.6 0.14 12.2 0.6 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Nop14 PF04147.12 GBG85059.1 - 0.095 10.9 8.9 0.11 10.7 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG85059.1 - 1 7.5 10.8 1.3 7.2 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG85059.1 - 4 6.8 13.8 5.2 6.4 13.8 1.1 1 0 0 1 1 1 0 SDA1 Peptidase_C13 PF01650.18 GBG85060.1 - 2.3e-45 155.1 0.3 3e-45 154.7 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family RPA_interact_N PF14766.6 GBG85060.1 - 9.6e-10 37.9 8.2 1.9e-09 37.0 8.2 1.5 1 0 0 1 1 1 1 Replication protein A interacting N-terminal ArgoMid PF16487.5 GBG85060.1 - 0.12 12.7 0.1 0.81 10.0 0.0 2.3 2 0 0 2 2 2 0 Mid domain of argonaute Peptidase_C80 PF11713.8 GBG85060.1 - 0.16 12.2 0.0 7.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase C80 family RPA_interact_M PF14767.6 GBG85061.1 - 6.1e-12 45.9 0.8 3.3e-11 43.6 0.8 2.2 1 1 0 1 1 1 1 Replication protein A interacting middle RPA_interact_C PF14768.6 GBG85061.1 - 0.00056 20.4 1.4 0.00056 20.4 1.4 2.3 2 1 0 2 2 2 1 Replication protein A interacting C-terminal DDE_Tnp_4 PF13359.6 GBG85062.1 - 1.9e-12 47.1 0.5 2.8e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85062.1 - 0.0002 21.1 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 GBG85064.1 - 4.3e-31 107.7 0.0 7.7e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85064.1 - 3.3e-16 59.5 0.0 5.2e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85064.1 - 2.5e-05 24.0 0.4 0.056 13.1 0.0 2.8 3 0 0 3 3 3 2 Transposase DDE domain RVT_1 PF00078.27 GBG85065.1 - 2.7e-32 112.1 0.0 4.1e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85065.1 - 4.5e-28 97.2 0.0 4.1e-13 49.2 0.0 2.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85065.1 - 1.7e-17 63.6 0.0 4.5e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85065.1 - 8.9e-13 48.5 0.0 3.3e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG85065.1 - 3.5e-12 46.1 0.0 6.6e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C48 PF02902.19 GBG85067.1 - 7e-09 35.8 0.4 1.4e-08 34.9 0.4 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GYD PF08734.11 GBG85068.1 - 0.0035 17.3 0.0 1.1 9.3 0.0 3.2 3 0 0 3 3 3 2 GYD domain AUDH_Cupin PF18637.1 GBG85068.1 - 0.55 10.2 4.7 4.7 7.2 1.5 2.4 1 1 1 2 2 2 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain zf-C2H2_4 PF13894.6 GBG85070.1 - 0.054 14.3 1.5 0.24 12.3 1.5 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Trypan_PARP PF05887.11 GBG85071.1 - 1.5 8.8 12.4 6.2 6.8 12.4 2.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDE_Tnp_4 PF13359.6 GBG85072.1 - 6e-28 97.5 0.0 8.6e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85072.1 - 8.6e-16 58.2 0.0 1.5e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85072.1 - 7.5e-07 29.0 0.4 0.0031 17.2 0.0 2.9 2 1 0 2 2 2 2 Transposase DDE domain Pap_E4 PF02711.14 GBG85072.1 - 0.073 14.0 1.7 0.13 13.2 1.7 1.3 1 0 0 1 1 1 0 E4 protein PLD_C PF12357.8 GBG85073.1 - 1.1e-25 89.3 0.0 2.1e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D C terminal C2 PF00168.30 GBG85073.1 - 5.4e-18 65.2 0.0 1.5e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 C2 domain PLDc PF00614.22 GBG85073.1 - 1.8e-15 56.4 0.4 7.9e-08 32.2 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG85073.1 - 1.4e-09 38.0 1.0 1.4e-07 31.5 0.1 3.2 2 1 0 2 2 2 1 PLD-like domain MatE PF01554.18 GBG85075.1 - 6.4e-54 181.9 26.6 1.4e-30 106.0 12.1 2.3 2 0 0 2 2 2 2 MatE Root_cap PF06830.11 GBG85076.1 - 6.5e-12 45.4 0.0 3.2e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Root cap PAN_4 PF14295.6 GBG85076.1 - 0.00017 21.4 1.5 0.00017 21.4 1.5 2.5 3 0 0 3 3 3 1 PAN domain PAN_1 PF00024.26 GBG85076.1 - 0.0021 18.0 1.3 0.0052 16.7 0.6 2.0 2 0 0 2 2 2 1 PAN domain SNARE PF05739.19 GBG85077.1 - 0.0055 16.7 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 SNARE domain GBP PF02263.19 GBG85078.1 - 3.8e-54 183.7 1.5 6.4e-53 179.7 0.0 2.8 2 1 0 3 3 3 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 GBG85078.1 - 8.3e-27 94.4 25.4 8.3e-27 94.4 25.4 5.7 1 1 4 5 5 5 1 Guanylate-binding protein, C-terminal domain F-box-like PF12937.7 GBG85079.1 - 5.1e-12 45.5 0.8 1e-11 44.5 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG85079.1 - 1.3e-09 37.7 0.2 3.4e-09 36.3 0.2 1.7 1 0 0 1 1 1 1 F-box domain CENP-B_dimeris PF09026.10 GBG85079.1 - 0.18 12.2 6.2 0.071 13.5 3.2 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 GBG85079.1 - 8.9 6.0 7.8 14 5.4 7.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein F-box-like PF12937.7 GBG85080.1 - 3.1e-12 46.2 0.8 6.5e-12 45.1 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG85080.1 - 7.2e-10 38.5 0.2 2.2e-09 36.9 0.2 1.8 1 0 0 1 1 1 1 F-box domain CENP-B_dimeris PF09026.10 GBG85080.1 - 0.047 14.1 3.2 0.047 14.1 3.2 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF688 PF05097.12 GBG85080.1 - 0.32 10.1 0.1 0.43 9.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Cwf_Cwc_15 PF04889.12 GBG85080.1 - 6.1 6.5 7.8 9.2 5.9 7.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NACHT PF05729.12 GBG85081.1 - 3.3e-06 27.1 0.1 2.1e-05 24.5 0.1 2.3 2 1 0 2 2 2 1 NACHT domain MACPF PF01823.19 GBG85081.1 - 4.6e-06 26.9 0.2 7.5e-05 22.9 0.2 2.2 1 1 0 1 1 1 1 MAC/Perforin domain AAA_16 PF13191.6 GBG85081.1 - 8.6e-05 23.0 0.2 0.001 19.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 GBG85081.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG85081.1 - 0.16 11.8 0.4 0.44 10.3 0.4 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 GBG85081.1 - 0.16 11.1 0.4 0.43 9.7 0.4 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.12 GBG85081.1 - 0.21 10.9 1.0 1.5 8.1 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 GBG85082.1 - 2.7e-06 27.4 0.1 1.8e-05 24.7 0.1 2.3 2 1 0 2 2 2 1 NACHT domain MACPF PF01823.19 GBG85082.1 - 3.9e-06 27.1 0.2 6.6e-05 23.1 0.2 2.1 1 1 0 1 1 1 1 MAC/Perforin domain AAA_16 PF13191.6 GBG85082.1 - 7.1e-05 23.2 0.3 0.00092 19.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 GBG85082.1 - 0.074 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG85082.1 - 0.16 11.7 0.4 0.4 10.5 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GBG85082.1 - 0.17 11.1 1.0 1.3 8.2 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 GBG85082.1 - 0.18 10.8 0.1 0.34 9.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DAP3 PF10236.9 GBG85082.1 - 0.19 10.9 0.4 0.39 9.8 0.4 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Chromo PF00385.24 GBG85083.1 - 0.00025 20.9 0.0 0.00058 19.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG85083.1 - 0.00045 20.5 0.4 0.17 12.1 0.0 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein DUF3006 PF11213.8 GBG85083.1 - 0.72 10.1 5.5 2.9 8.2 1.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3006) TMEM247 PF15444.6 GBG85083.1 - 1.7 8.6 5.5 0.76 9.8 0.1 2.5 2 1 0 2 2 2 0 Transmembrane protein 247 PP2 PF14299.6 GBG85084.1 - 3.7e-15 56.2 0.0 6.1e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Phloem protein 2 F-box-like PF12937.7 GBG85084.1 - 0.00015 21.6 0.1 0.0003 20.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG85084.1 - 0.036 14.0 2.8 0.046 13.6 0.2 2.5 3 0 0 3 3 3 0 F-box domain RVT_1 PF00078.27 GBG85085.1 - 5.1e-26 91.6 0.0 8e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG85085.1 - 0.0029 17.5 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 GBG85086.1 - 1e-07 32.4 0.0 1.8e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85086.1 - 2.8e-05 24.7 0.0 6.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85086.1 - 0.037 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG85086.1 - 0.083 13.2 0.0 0.23 11.8 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF975 PF06161.11 GBG85088.1 - 3.3 7.4 10.6 4.8 6.9 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) RCC1 PF00415.18 GBG85089.1 - 2e-71 236.4 34.0 4.1e-13 49.7 0.1 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG85089.1 - 2.3e-28 97.3 38.8 5.1e-06 26.1 1.4 8.3 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 GBG85089.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like SUKH-3 PF14433.6 GBG85089.1 - 5.7 7.4 5.9 22 5.5 0.0 4.2 5 1 1 6 6 6 0 SUKH-3 immunity protein RCC1 PF00415.18 GBG85090.1 - 9.8e-72 237.4 34.0 3.7e-13 49.9 0.1 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG85090.1 - 1.4e-28 98.1 39.0 4.7e-06 26.3 1.4 8.3 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 GBG85090.1 - 0.071 13.0 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 F-box-like SUKH-3 PF14433.6 GBG85090.1 - 3.8 8.0 5.9 20 5.6 0.0 4.3 5 1 1 6 6 6 0 SUKH-3 immunity protein RabGAP-TBC PF00566.18 GBG85092.1 - 3.8e-41 141.1 0.1 5.2e-41 140.7 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NETI PF14044.6 GBG85092.1 - 0.13 12.0 0.0 9.5 6.0 0.0 2.3 2 0 0 2 2 2 0 NETI protein RabGAP-TBC PF00566.18 GBG85093.1 - 7.2e-41 140.2 0.0 9e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NETI PF14044.6 GBG85093.1 - 0.11 12.3 0.0 8.5 6.2 0.0 2.3 2 0 0 2 2 2 0 NETI protein Integrase_H2C2 PF17921.1 GBG85094.1 - 2.5e-15 56.3 0.2 6.8e-15 54.9 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85094.1 - 3.1e-07 30.6 0.0 8.8e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG85094.1 - 9.1e-06 26.1 0.1 2.9e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG85094.1 - 0.0072 16.5 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG85094.1 - 0.012 16.2 0.0 0.033 14.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG85094.1 - 0.022 15.0 0.0 0.068 13.5 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85094.1 - 0.029 14.2 0.3 0.029 14.2 0.3 1.9 2 0 0 2 2 2 0 Aspartyl protease PPP4R2 PF09184.11 GBG85094.1 - 0.62 9.6 7.3 1.5 8.3 7.3 1.6 1 0 0 1 1 1 0 PPP4R2 XPC-binding PF09280.11 GBG85094.1 - 0.99 9.2 4.1 5.5 6.8 1.3 2.4 2 0 0 2 2 2 0 XPC-binding domain Prothymosin PF03247.14 GBG85094.1 - 2.6 8.5 20.1 11 6.5 20.1 2.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family WD40 PF00400.32 GBG85095.1 - 7.9e-13 48.7 8.6 0.00054 20.7 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat RT_RNaseH_2 PF17919.1 GBG85095.1 - 1.1e-08 35.0 0.0 8.2e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85095.1 - 5.7e-07 29.8 0.0 1.6e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase ANAPC4_WD40 PF12894.7 GBG85095.1 - 1.8e-05 24.9 0.0 0.031 14.6 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 GBG85095.1 - 0.0038 16.9 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 CNH domain Nop14 PF04147.12 GBG85095.1 - 0.14 10.3 21.0 0.21 9.8 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG85095.1 - 1.2 7.4 19.2 1.7 6.8 19.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG85095.1 - 1.7 8.0 23.8 2.6 7.4 23.8 1.2 1 0 0 1 1 1 0 SDA1 Myb_DNA-bind_4 PF13837.6 GBG85096.1 - 1.4e-11 44.6 0.6 6.4e-11 42.5 0.8 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85096.1 - 0.0009 19.5 0.1 0.0032 17.7 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG85096.1 - 0.58 10.3 6.3 0.49 10.5 1.3 3.1 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG85097.1 - 1.5e-12 47.4 0.0 2.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85097.1 - 2.3e-06 27.3 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein WD40 PF00400.32 GBG85098.1 - 1.9e-15 56.9 2.9 0.0055 17.5 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF829 PF05705.14 GBG85099.1 - 1e-32 114.0 0.0 1.3e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF829 PF05705.14 GBG85100.1 - 8.7e-27 94.6 0.0 1.1e-26 94.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PBP PF01161.20 GBG85103.1 - 8.4e-36 123.2 0.1 1.1e-35 122.9 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein NOA36 PF06524.12 GBG85104.1 - 0.095 12.0 2.7 0.11 11.8 2.7 1.1 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 GBG85104.1 - 0.15 11.9 1.9 0.16 11.8 1.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PGA2 PF07543.12 GBG85104.1 - 0.46 10.5 4.8 0.56 10.2 4.8 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Radial_spoke PF04712.12 GBG85104.1 - 0.57 9.1 7.6 0.58 9.0 7.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 GBG85104.1 - 0.64 8.1 6.3 0.6 8.1 6.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi S-antigen PF05756.11 GBG85104.1 - 0.64 10.4 4.4 0.86 10.0 4.4 1.2 1 0 0 1 1 1 0 S-antigen protein Ribosomal_60s PF00428.19 GBG85104.1 - 0.65 10.6 9.1 1.1 10.0 9.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop14 PF04147.12 GBG85104.1 - 4.3 5.4 7.7 4.4 5.4 7.7 1.0 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG85105.1 - 8.7e-25 87.5 0.0 1.6e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85105.1 - 5.4e-11 42.4 0.0 1.5e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG85105.1 - 0.00032 20.9 1.0 0.0044 17.3 0.1 3.4 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG85105.1 - 0.0079 16.5 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4187 PF13821.6 GBG85105.1 - 0.16 11.8 4.1 0.062 13.1 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) RVP_2 PF08284.11 GBG85105.1 - 0.19 11.5 0.0 0.51 10.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease FAM76 PF16046.5 GBG85105.1 - 2.8 7.2 7.2 5.4 6.3 7.2 1.3 1 0 0 1 1 1 0 FAM76 protein Peptidase_A22B PF04258.13 GBG85107.1 - 6.9e-87 291.6 7.4 8e-87 291.4 7.4 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 GBG85107.1 - 2.2e-05 24.1 8.3 2.2e-05 24.1 8.3 2.5 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 GBG85107.1 - 0.0075 15.1 2.2 0.0075 15.1 2.2 1.7 2 0 0 2 2 2 1 Presenilin CDC45 PF02724.14 GBG85109.1 - 0.00076 17.9 13.6 0.00097 17.6 13.6 1.2 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 GBG85109.1 - 0.0023 16.5 17.4 0.0023 16.5 17.4 1.5 2 0 0 2 2 2 1 Mpp10 protein DUF2151 PF10221.9 GBG85109.1 - 0.012 14.2 15.7 0.021 13.5 15.7 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Cas_NE0113 PF09623.10 GBG85109.1 - 0.13 11.9 4.5 2.7 7.6 1.5 2.4 1 1 1 2 2 2 0 CRISPR-associated protein NE0113 (Cas_NE0113) Dsh_C PF12316.8 GBG85109.1 - 0.28 11.6 11.7 8.3 6.8 11.5 2.3 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Peptidase_S64 PF08192.11 GBG85109.1 - 0.29 9.6 5.0 0.32 9.4 5.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Zip PF02535.22 GBG85109.1 - 0.36 10.0 4.9 0.48 9.6 4.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NOA36 PF06524.12 GBG85109.1 - 1.7 7.9 20.7 4.2 6.6 20.7 1.7 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GBG85109.1 - 1.8 6.6 28.5 3 6.0 28.5 1.3 1 1 0 1 1 1 0 Nop14-like family Roughex PF06020.11 GBG85109.1 - 1.9 7.5 17.4 3.1 6.8 17.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Mitofilin PF09731.9 GBG85109.1 - 3.3 6.4 23.3 4.7 5.9 23.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NPR3 PF03666.13 GBG85109.1 - 9.2 4.9 20.0 2 7.1 16.9 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SNF2_N PF00176.23 GBG85110.1 - 4.2e-52 177.0 0.0 5.7e-40 137.1 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG85110.1 - 8.3e-19 68.0 0.0 2e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG85110.1 - 0.0021 18.1 0.0 0.029 14.4 0.0 2.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GBG85110.1 - 0.015 14.4 0.0 0.11 11.7 0.0 2.3 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 ORC3_N PF07034.11 GBG85110.1 - 0.98 8.4 3.4 2.3 7.2 3.4 1.6 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus LSM PF01423.22 GBG85111.1 - 6.3e-16 57.8 0.0 8.4e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GBG85111.1 - 0.00066 19.8 0.0 0.00097 19.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RVT_1 PF00078.27 GBG85112.1 - 4.4e-63 212.8 0.5 1.4e-32 113.1 0.2 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG85112.1 - 2.3e-19 69.2 0.4 6e-19 67.9 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG85112.1 - 1e-16 61.1 1.8 4.8e-16 58.9 1.8 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG85112.1 - 4.7e-09 36.1 0.0 5.3e-06 26.2 0.0 2.8 3 0 0 3 3 3 2 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG85112.1 - 6.3e-09 35.8 0.2 3.4e-08 33.4 0.2 2.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG85112.1 - 6.3e-05 23.2 0.9 0.51 10.6 0.0 4.0 2 0 0 2 2 2 2 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG85112.1 - 0.00065 20.3 1.3 0.025 15.2 0.0 3.4 3 0 0 3 3 3 1 Aspartyl protease zf-H2C2 PF09337.10 GBG85112.1 - 0.0012 19.0 0.1 0.0054 16.9 0.1 2.2 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG85112.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG85112.1 - 0.0047 17.5 0.0 0.0047 17.5 0.0 3.2 5 0 0 5 5 3 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG85112.1 - 0.083 12.7 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG85113.1 - 3.4e-34 116.9 0.1 6.9e-34 115.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85113.1 - 1.9e-30 105.3 0.1 4e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85113.1 - 2.6e-18 65.9 0.2 5.4e-18 64.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85113.1 - 2.6e-16 59.9 0.0 1.8e-15 57.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG85113.1 - 1.4e-10 41.1 0.2 3e-10 40.0 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG85113.1 - 0.15 11.9 0.3 0.58 10.0 0.1 2.2 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH PF17917.1 GBG85114.1 - 7.1e-30 103.4 0.8 1.3e-28 99.4 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85114.1 - 4.4e-29 100.5 0.1 1.8e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DENN PF02141.21 GBG85114.1 - 2.6e-25 89.5 1.8 5.2e-21 75.5 0.6 2.5 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 GBG85114.1 - 1.6e-07 31.9 0.1 3.8e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 GBG85114.1 - 8.6e-07 28.9 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 dDENN domain Phage_GPO PF05929.11 GBG85114.1 - 0.24 11.0 0.0 0.24 11.0 0.0 3.2 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH PF17917.1 GBG85115.1 - 6.8e-30 103.5 0.8 1.2e-28 99.4 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85115.1 - 4.3e-29 100.5 0.1 1.8e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DENN PF02141.21 GBG85115.1 - 2.5e-25 89.5 1.8 5e-21 75.5 0.6 2.4 2 0 0 2 2 2 2 DENN (AEX-3) domain dDENN PF03455.19 GBG85115.1 - 8.4e-07 28.9 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 dDENN domain Phage_GPO PF05929.11 GBG85115.1 - 0.24 11.0 0.0 0.24 11.0 0.0 3.2 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF5534 PF17686.1 GBG85116.1 - 0.027 14.7 0.3 0.035 14.4 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5534) Paf1 PF03985.13 GBG85116.1 - 0.045 12.8 1.7 0.048 12.7 1.7 1.0 1 0 0 1 1 1 0 Paf1 RT_RNaseH_2 PF17919.1 GBG85117.1 - 3.7e-23 81.4 0.1 9.4e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85117.1 - 3.6e-20 72.2 0.0 8e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85117.1 - 9.5e-16 57.7 2.7 1.3e-15 57.2 0.3 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85117.1 - 2.7e-12 46.7 0.5 6.9e-08 32.3 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG85117.1 - 2e-10 40.9 0.0 5.7e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG85117.1 - 6.1e-08 33.1 0.0 2.5e-07 31.2 0.0 2.2 3 0 0 3 3 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85117.1 - 1.1e-07 32.3 0.0 3.4e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85117.1 - 4.6e-06 26.4 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85117.1 - 2.2e-05 24.2 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG85117.1 - 0.012 15.8 0.2 0.034 14.4 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG85117.1 - 0.051 13.8 0.4 0.93 9.8 0.0 3.0 2 0 0 2 2 2 0 Retrotransposon gag protein SDA1 PF05285.12 GBG85118.1 - 0.00084 18.9 32.2 0.00086 18.8 32.2 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GBG85118.1 - 0.0086 15.5 27.0 0.008 15.6 27.0 1.1 1 0 0 1 1 1 1 BUD22 SAPS PF04499.15 GBG85118.1 - 0.032 13.0 5.0 0.032 13.0 5.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG85118.1 - 8.2 4.5 43.6 9.7 4.3 43.6 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH PF17917.1 GBG85119.1 - 1.7e-26 92.5 0.0 3.5e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85119.1 - 3.3e-25 88.0 0.0 5.6e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85119.1 - 1.5e-14 53.9 0.0 3.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85119.1 - 3e-12 46.8 0.0 9e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG85119.1 - 0.0066 16.6 0.1 0.015 15.5 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG85122.1 - 1.4e-21 76.8 0.0 2.4e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85122.1 - 4.8e-15 55.4 0.0 9.8e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85122.1 - 1.6e-14 53.9 0.1 4.4e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85122.1 - 5.7e-12 45.6 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG85122.1 - 9.4e-05 22.6 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG85122.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like RT_RNaseH PF17917.1 GBG85123.1 - 1.1e-16 61.0 0.0 2.8e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85123.1 - 1.3e-13 50.8 0.0 2.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG85123.1 - 3.3e-05 24.4 0.1 9.9e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85123.1 - 0.0022 18.6 0.1 0.0052 17.4 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85123.1 - 0.0031 17.3 0.1 0.0052 16.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG85123.1 - 0.51 10.5 2.2 1 9.6 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG85124.1 - 4.2e-05 24.0 0.0 9.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85124.1 - 4.3e-05 24.1 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG85124.1 - 0.1 12.3 0.2 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG85124.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG85125.1 - 2e-22 79.1 0.0 4.3e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85125.1 - 4e-18 65.3 0.1 1.1e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85125.1 - 9.7e-17 61.3 0.0 2.7e-12 46.9 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 GBG85125.1 - 9.1e-12 45.0 0.2 1.8e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85125.1 - 6.6e-10 39.2 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG85125.1 - 0.0045 17.2 0.0 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger DUF1478 PF07349.11 GBG85125.1 - 0.022 14.7 0.2 6.9 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1478) DUF1564 PF07600.11 GBG85125.1 - 0.083 12.6 1.1 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DUF1904 PF08921.11 GBG85125.1 - 0.1 13.0 0.3 0.75 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) Cytomega_UL20A PF05984.12 GBG85125.1 - 2 8.7 4.5 8.8 6.7 1.1 2.6 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein AUX_IAA PF02309.16 GBG85126.1 - 2.3e-24 86.5 0.0 2.7e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 AUX/IAA family RT_RNaseH PF17917.1 GBG85127.1 - 1.9e-18 66.7 0.0 3.4e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85127.1 - 1.1e-16 60.7 0.0 2.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85127.1 - 3e-13 49.7 0.5 8.2e-13 48.3 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RBD PF02196.15 GBG85127.1 - 0.18 11.9 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain Pro_isomerase PF00160.21 GBG85128.1 - 4.5 7.5 7.4 0.29 11.4 0.3 2.5 2 2 0 2 2 2 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RVT_1 PF00078.27 GBG85129.1 - 6.3e-28 97.8 0.2 1.5e-27 96.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85129.1 - 1.7e-22 79.7 0.0 5.5e-22 78.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85129.1 - 3e-22 78.5 0.0 1.3e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG85129.1 - 4e-06 27.4 0.0 1.2e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG85129.1 - 1.2e-05 25.3 0.0 2.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG85129.1 - 9.4e-05 22.2 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG85129.1 - 0.00076 20.0 0.0 0.003 18.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG85129.1 - 0.0013 19.0 0.0 0.0049 17.1 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG85129.1 - 0.073 13.2 4.8 0.16 12.0 4.8 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Asp_protease PF09668.10 GBG85129.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.12 GBG85129.1 - 2.3 8.9 7.0 0.52 11.0 0.7 3.1 3 1 1 4 4 4 0 SlyX DUF659 PF04937.15 GBG85131.1 - 6.7e-08 32.5 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG85131.1 - 1.6e-06 27.8 0.1 3.1e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG85132.1 - 1.7e-32 112.8 0.1 2.7e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG85132.1 - 5.5e-06 26.2 0.0 1.4e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG85132.1 - 2.2e-05 25.0 0.0 5.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85132.1 - 0.00041 20.9 0.3 0.0015 19.1 0.1 2.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG85132.1 - 0.058 13.2 0.0 0.19 11.5 0.0 1.9 1 1 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG85132.1 - 0.068 13.0 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Myb_DNA-bind_4 PF13837.6 GBG85133.1 - 1.5e-08 34.9 5.6 1.6e-08 34.8 3.9 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain bPH_6 PF10756.9 GBG85133.1 - 0.0002 21.4 0.2 0.006 16.7 0.0 2.7 2 0 0 2 2 2 1 Bacterial PH domain TFIIA PF03153.13 GBG85133.1 - 0.00024 21.3 2.0 0.00024 21.3 2.0 1.7 2 0 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit MADF_DNA_bdg PF10545.9 GBG85133.1 - 0.025 14.9 0.6 0.065 13.5 0.6 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DNA_pol_phi PF04931.13 GBG85133.1 - 0.048 11.8 16.7 0.091 10.9 16.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG85133.1 - 0.11 10.8 5.7 0.17 10.1 5.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG85133.1 - 0.15 10.3 7.9 0.22 9.7 7.9 1.3 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-binding PF00249.31 GBG85133.1 - 0.17 12.1 1.6 8.5 6.7 0.7 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain FAM176 PF14851.6 GBG85133.1 - 0.32 10.6 1.5 0.94 9.1 1.5 1.8 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 GBG85133.1 - 0.55 10.2 5.3 1.5 8.8 5.3 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal PPP4R2 PF09184.11 GBG85133.1 - 0.61 9.6 7.2 1.1 8.8 7.2 1.5 1 0 0 1 1 1 0 PPP4R2 GCIP PF13324.6 GBG85133.1 - 0.64 9.6 5.0 1.2 8.7 5.0 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting BUD22 PF09073.10 GBG85133.1 - 0.67 9.2 8.5 1.1 8.5 8.5 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG85133.1 - 1.9 7.8 9.6 5.3 6.4 9.6 1.7 1 0 0 1 1 1 0 SDA1 Herpes_LMP1 PF05297.11 GBG85133.1 - 5.2 6.1 12.0 9.3 5.3 12.0 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4360 PF14273.6 GBG85136.1 - 8.3e-25 87.7 0.0 1e-24 87.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SP2 PF03014.14 GBG85136.1 - 0.22 9.9 0.0 0.27 9.6 0.0 1.0 1 0 0 1 1 1 0 Structural protein 2 DUF4360 PF14273.6 GBG85138.1 - 1.2e-34 119.8 0.0 1.6e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) BUD22 PF09073.10 GBG85139.1 - 4.5 6.5 37.2 0.64 9.3 23.5 2.2 2 0 0 2 2 2 0 BUD22 PPP4R2 PF09184.11 GBG85139.1 - 5.7 6.4 33.9 2.9 7.4 3.8 2.4 2 0 0 2 2 2 0 PPP4R2 Nop14 PF04147.12 GBG85139.1 - 6.3 4.9 36.3 0.43 8.7 22.8 2.1 2 0 0 2 2 2 0 Nop14-like family DUF4360 PF14273.6 GBG85141.1 - 1.3e-30 106.6 0.0 1.5e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG85142.1 - 4.3e-27 95.1 0.0 6.4e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) TFIIS_C PF01096.18 GBG85143.1 - 0.095 12.6 0.3 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) LRRC37AB_C PF14914.6 GBG85143.1 - 0.38 10.6 8.0 0.73 9.7 8.0 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Casc1_N PF15927.5 GBG85143.1 - 0.57 9.8 16.9 2 8.1 16.9 2.0 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Presenilin PF01080.17 GBG85143.1 - 1.1 8.0 3.3 1.2 7.9 3.3 1.1 1 0 0 1 1 1 0 Presenilin ARGLU PF15346.6 GBG85143.1 - 1.2 9.0 29.9 0.076 12.9 17.7 3.1 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 Connexin PF00029.19 GBG85143.1 - 4.3 7.0 5.6 8 6.1 5.6 1.4 1 0 0 1 1 1 0 Connexin DUF4360 PF14273.6 GBG85144.1 - 1.6e-30 106.3 0.0 3.7e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) N6_N4_Mtase PF01555.18 GBG85144.1 - 2.6e-06 27.3 0.0 4.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 DNA methylase FlaC_arch PF05377.11 GBG85145.1 - 0.011 16.2 1.2 0.031 14.6 1.2 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 GBG85145.1 - 0.027 14.1 1.5 0.027 14.1 1.5 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Syntaxin_2 PF14523.6 GBG85145.1 - 0.19 12.1 4.1 22 5.5 0.6 3.1 3 0 0 3 3 3 0 Syntaxin-like protein UPF0449 PF15136.6 GBG85145.1 - 0.25 11.8 0.1 0.25 11.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF5320 PF17253.2 GBG85145.1 - 0.43 11.7 0.1 0.43 11.7 0.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Ax_dynein_light PF10211.9 GBG85145.1 - 3.5 7.5 14.3 0.66 9.9 0.2 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain TRAP-gamma PF07074.12 GBG85145.1 - 3.5 7.1 4.2 7.1 6.2 4.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) OmpH PF03938.14 GBG85145.1 - 3.8 7.9 14.5 1.3 9.3 7.0 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) PIN_10 PF18478.1 GBG85146.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 PIN like domain Rz1 PF06085.11 GBG85146.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor RT_RNaseH PF17917.1 GBG85147.1 - 1.9e-22 79.5 0.0 7.3e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85147.1 - 2e-20 72.7 0.0 5.5e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85147.1 - 9.1e-10 38.4 0.0 1.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG85147.1 - 0.013 16.0 0.1 0.031 14.8 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease gag-asp_proteas PF13975.6 GBG85148.1 - 1.3e-05 25.7 0.1 2.6e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG85148.1 - 0.0034 17.2 0.1 0.0057 16.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG85148.1 - 0.0046 17.6 0.1 0.01 16.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85148.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4360 PF14273.6 GBG85149.1 - 5.5e-43 146.9 0.0 1.2e-42 145.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4360) OppC_N PF12911.7 GBG85149.1 - 0.046 13.7 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C RskA PF10099.9 GBG85149.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Peptidase_C48 PF02902.19 GBG85151.1 - 6.7e-18 65.3 0.0 9.8e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Autophagy_N PF03986.13 GBG85152.1 - 0.37 10.7 0.1 0.37 10.7 0.1 2.7 2 1 1 3 3 3 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF1041 PF06292.17 GBG85152.1 - 0.82 10.1 8.1 0.61 10.5 1.7 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) Tho2 PF11262.8 GBG85153.1 - 1.5e-95 319.9 3.4 1.5e-95 319.9 3.4 3.1 3 1 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 GBG85153.1 - 4.5e-40 137.9 11.0 1e-21 77.3 0.0 3.6 3 0 0 3 3 3 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 GBG85153.1 - 2.5e-28 98.0 2.1 1.1e-27 95.9 0.1 2.7 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Tho2 PF11262.8 GBG85154.1 - 1.6e-95 319.8 3.4 1.6e-95 319.8 3.4 2.9 3 1 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 GBG85154.1 - 1.5e-40 139.5 9.6 1.1e-21 77.2 0.0 3.6 3 0 0 3 3 3 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 GBG85154.1 - 2.7e-28 97.9 2.1 1.1e-27 95.8 0.1 2.7 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Nup84_Nup100 PF04121.13 GBG85155.1 - 2.4e-69 234.3 0.0 3.1e-52 177.7 0.0 3.9 4 0 0 4 4 4 4 Nuclear pore protein 84 / 107 Sel1 PF08238.12 GBG85156.1 - 6e-56 185.6 38.5 2.3e-06 28.1 2.2 11.8 11 1 0 11 11 11 10 Sel1 repeat DUF2859 PF11072.8 GBG85156.1 - 0.0019 18.0 0.8 0.0058 16.4 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2859) Sel1 PF08238.12 GBG85157.1 - 3.1e-38 129.3 34.7 0.00034 21.2 3.2 10.5 10 0 0 10 10 10 10 Sel1 repeat HAUS-augmin3 PF14932.6 GBG85157.1 - 0.045 13.3 3.5 0.082 12.5 3.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 GBG85157.1 - 0.1 13.3 1.6 0.28 11.9 1.6 1.7 1 0 0 1 1 1 0 Initiation control protein YabA SKA1 PF07160.12 GBG85157.1 - 0.19 11.5 1.6 0.39 10.5 1.6 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 S1 PF00575.23 GBG85158.1 - 8.9e-12 45.2 4.0 0.0051 17.1 0.0 3.6 3 0 0 3 3 3 3 S1 RNA binding domain PCB_OB PF17092.5 GBG85158.1 - 0.027 15.2 0.1 11 6.8 0.0 2.7 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain CSRNP_N PF16019.5 GBG85159.1 - 0.007 16.3 0.2 0.0076 16.2 0.2 1.0 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus COX14 PF14880.6 GBG85159.1 - 0.44 10.4 2.3 0.76 9.7 2.3 1.5 1 1 0 1 1 1 0 Cytochrome oxidase c assembly BRO1 PF03097.18 GBG85160.1 - 2e-10 40.1 0.0 4.7e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 BRO1-like domain Pkinase PF00069.25 GBG85161.1 - 1e-28 100.5 0.0 1.4e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG85161.1 - 2.9e-13 49.7 0.0 4.8e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 GBG85161.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 GBG85161.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-LYAR PF08790.11 GBG85162.1 - 1.2e-11 44.3 2.0 1.2e-11 44.3 2.0 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-met PF12874.7 GBG85162.1 - 5.7e-06 26.5 1.3 5.7e-06 26.5 1.3 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GBG85162.1 - 0.016 15.5 0.2 0.016 15.5 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-ACC PF17848.1 GBG85162.1 - 0.062 13.4 0.3 0.062 13.4 0.3 1.9 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain AKAP95 PF04988.12 GBG85162.1 - 0.085 13.1 0.1 0.58 10.4 0.0 2.5 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 GBG85162.1 - 0.22 11.9 0.1 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GBG85162.1 - 1.6 9.8 6.5 41 5.4 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 GBG85162.1 - 1.9 8.2 4.7 0.49 10.1 0.2 2.4 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 GBG85162.1 - 4.5 7.9 7.2 2.5 8.7 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Pkinase PF00069.25 GBG85163.1 - 6.1e-06 25.8 0.0 2.1e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain PSI_PSAK PF01241.18 GBG85164.1 - 8.4e-15 54.5 1.0 1.3e-14 53.9 1.0 1.3 1 0 0 1 1 1 1 Photosystem I psaG / psaK Helicase_C PF00271.31 GBG85165.1 - 4.6e-24 84.9 0.0 9.5e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GBG85165.1 - 3.2e-17 62.9 1.2 1.2e-13 51.2 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 GBG85165.1 - 0.00086 19.4 0.0 0.0044 17.0 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GBG85165.1 - 0.0048 16.6 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.23 GBG85165.1 - 0.0092 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_11 PF13086.6 GBG85165.1 - 0.27 11.0 0.0 0.27 11.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Na_trans_assoc PF06512.13 GBG85165.1 - 7.5 6.8 22.8 0.34 11.2 8.6 2.6 2 0 0 2 2 2 0 Sodium ion transport-associated DDE_Tnp_4 PF13359.6 GBG85166.1 - 4.6e-23 81.6 0.0 8.9e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85166.1 - 3.9e-11 43.0 0.0 6.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85166.1 - 0.00035 20.3 0.3 0.0062 16.2 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG85167.1 - 1.5e-09 38.1 4.8 2.7e-09 37.3 1.4 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85167.1 - 0.0002 21.6 3.1 0.003 17.8 1.0 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG85167.1 - 0.0012 18.8 0.6 0.0035 17.4 0.6 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SNF2_N PF00176.23 GBG85168.1 - 2.2e-42 145.0 0.0 2.2e-42 145.0 0.0 4.2 3 2 1 5 5 5 2 SNF2 family N-terminal domain MCM PF00493.23 GBG85169.1 - 0.077 12.1 2.2 0.096 11.8 2.2 1.1 1 0 0 1 1 1 0 MCM P-loop domain Helicase_C PF00271.31 GBG85170.1 - 4.9e-17 62.3 0.0 9.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2817 PF10994.8 GBG85170.1 - 0.047 13.1 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Bax1-I PF01027.20 GBG85171.1 - 9.6e-44 149.7 28.3 1.1e-43 149.5 28.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PRK PF00485.18 GBG85172.1 - 5.2e-78 261.3 0.0 9.7e-78 260.4 0.0 1.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 GBG85172.1 - 0.09 13.1 0.0 0.9 9.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain RT_RNaseH PF17917.1 GBG85173.1 - 2.5e-21 75.9 0.0 7.3e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85173.1 - 1.1e-20 73.5 0.0 2.5e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85173.1 - 9.9e-15 54.4 0.5 2.3e-14 53.2 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85173.1 - 5.4e-08 32.6 0.0 9e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG85173.1 - 1.8e-06 28.4 0.1 5.4e-06 26.9 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85173.1 - 0.00065 20.3 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85173.1 - 0.0093 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85173.1 - 0.048 13.5 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease WD40 PF00400.32 GBG85174.1 - 1.3e-51 171.4 17.6 8.2e-09 36.0 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG85174.1 - 6.6e-16 58.4 0.1 0.0047 17.2 0.0 5.6 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG85174.1 - 9.7e-05 22.3 0.1 0.4 10.5 0.0 3.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GBG85174.1 - 0.00019 20.2 3.9 0.0054 15.4 0.1 3.8 4 1 1 5 5 5 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GBG85174.1 - 0.0091 15.0 0.1 2.4 7.0 0.0 3.3 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GBG85174.1 - 0.014 14.8 0.0 3.9 6.7 0.0 3.8 5 0 0 5 5 5 0 WD40-like domain RAB3GAP2_N PF14655.6 GBG85174.1 - 0.038 13.3 0.0 1.4 8.1 0.0 2.2 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.6 GBG85174.1 - 0.097 12.0 1.2 16 4.7 0.1 3.1 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 GBG85174.1 - 0.099 11.5 0.6 0.28 10.1 0.2 1.8 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain RT_RNaseH_2 PF17919.1 GBG85175.1 - 1.9e-15 56.7 0.0 1.5e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85175.1 - 7.1e-15 55.2 0.0 4.9e-13 49.3 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85175.1 - 1.4e-08 34.5 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG85175.1 - 7.9e-05 23.1 0.0 0.00016 22.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85175.1 - 0.0024 18.5 0.0 0.005 17.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85175.1 - 0.041 13.7 0.6 0.081 12.7 0.6 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG85176.1 - 2.7e-30 103.1 37.8 5.9e-07 29.3 1.1 5.5 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_5 PF14787.6 GBG85176.1 - 7.3e-10 38.4 35.4 0.018 14.7 1.7 5.4 5 0 0 5 5 5 5 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG85176.1 - 1.8e-09 37.2 25.4 0.045 13.5 0.5 5.4 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 GBG85176.1 - 5.4e-07 29.5 19.8 0.99 9.4 2.1 5.4 4 1 1 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 GBG85176.1 - 3.4e-05 23.6 33.8 0.28 11.0 1.1 5.5 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 GBG85176.1 - 0.0019 18.0 28.6 0.6 10.0 1.4 4.8 5 0 0 5 5 5 4 Zinc knuckle VIGSSK PF14773.6 GBG85177.1 - 0.00057 19.9 0.7 0.0039 17.3 0.2 2.7 1 1 1 2 2 2 1 Helicase-associated putative binding domain, C-terminal Nop14 PF04147.12 GBG85177.1 - 0.0011 17.4 9.5 0.0012 17.2 9.5 1.0 1 0 0 1 1 1 1 Nop14-like family PIEZO PF15917.5 GBG85177.1 - 0.72 9.3 4.2 0.92 8.9 4.1 1.3 1 1 0 1 1 1 0 Piezo Integrase_H2C2 PF17921.1 GBG85178.1 - 3e-13 49.7 0.4 7.7e-13 48.3 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85178.1 - 5.9e-11 42.6 0.0 7.1e-10 39.1 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG85178.1 - 5.8e-07 29.5 0.0 2e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85178.1 - 6.6e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85178.1 - 1.5e-05 25.2 0.0 0.00019 21.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Jnk-SapK_ap_N PF09744.9 GBG85179.1 - 0.014 15.7 4.5 0.039 14.2 4.5 1.7 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Peptidase_C2 PF00648.21 GBG85181.1 - 7.5e-108 360.0 0.4 1e-107 359.6 0.4 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 GBG85181.1 - 1.8e-25 89.8 0.0 3.5e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 GBG85181.1 - 8.8e-13 48.4 0.1 1.7e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 C2 domain BUD22 PF09073.10 GBG85183.1 - 0.0035 16.7 4.2 0.0035 16.7 4.2 2.4 2 0 0 2 2 2 1 BUD22 Nop14 PF04147.12 GBG85183.1 - 0.0096 14.2 7.3 0.092 10.9 7.0 2.2 2 0 0 2 2 2 1 Nop14-like family Zip PF02535.22 GBG85183.1 - 0.029 13.6 3.8 0.058 12.6 3.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF5542 PF17696.1 GBG85183.1 - 0.082 13.0 0.2 0.082 13.0 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5542) CDC45 PF02724.14 GBG85183.1 - 0.61 8.3 5.3 1.4 7.1 5.3 1.6 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG85184.1 - 1.1e-20 73.5 0.0 2.7e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85184.1 - 4.3e-20 71.9 0.0 9e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85184.1 - 7.5e-14 51.6 0.3 1.8e-13 50.3 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85184.1 - 7.8e-09 35.8 0.0 2.4e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG85184.1 - 1.5e-08 35.1 0.0 4.9e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG85184.1 - 7e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG85184.1 - 4.4e-06 27.2 0.1 1.5e-05 25.6 0.0 2.0 2 0 0 2 2 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG85184.1 - 0.0006 19.8 8.8 0.097 12.8 1.6 2.7 2 0 0 2 2 2 2 Zinc knuckle Asp_protease PF09668.10 GBG85184.1 - 0.00071 19.4 0.3 0.002 17.9 0.2 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG85184.1 - 0.017 15.4 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG85184.1 - 0.24 11.7 0.5 0.62 10.3 0.5 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Corona_nucleoca PF00937.18 GBG85185.1 - 0.0041 16.2 0.8 0.012 14.7 0.8 1.7 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein CVNH PF08881.10 GBG85186.1 - 0.08 13.6 0.2 23 5.7 0.3 3.9 1 1 1 2 2 2 0 CVNH domain PBP-Tp47_a PF14889.6 GBG85187.1 - 0.64 9.6 8.4 0.44 10.2 3.2 2.2 1 1 1 2 2 2 0 Penicillin-binding protein Tp47 domain a FERM_f0 PF16511.5 GBG85187.1 - 5.5 7.4 14.6 28 5.1 0.6 4.4 1 1 3 4 4 4 0 N-terminal or F0 domain of Talin-head FERM Trypsin PF00089.26 GBG85188.1 - 3.6e-32 112.0 0.3 7.7e-32 110.9 0.3 1.5 2 0 0 2 2 2 1 Trypsin Asp_protease_2 PF13650.6 GBG85188.1 - 0.0072 16.9 0.1 0.036 14.7 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG85189.1 - 0.007 16.6 0.8 0.038 14.2 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein CENP-K PF11802.8 GBG85189.1 - 0.13 11.8 3.2 0.21 11.1 3.2 1.3 1 0 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 GBG85189.1 - 0.6 10.0 8.7 1.1 9.2 8.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nramp PF01566.18 GBG85190.1 - 2.5e-111 372.1 18.3 3.1e-111 371.8 18.3 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein RVT_1 PF00078.27 GBG85190.1 - 7.1e-19 68.2 0.2 6.7e-12 45.4 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Mt_ATP_synt PF15704.5 GBG85191.1 - 4.8e-51 173.3 11.6 6e-51 173.0 11.6 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase subunit Mitofilin PF09731.9 GBG85191.1 - 0.0026 16.7 8.3 0.0033 16.3 8.3 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4897 PF16238.5 GBG85191.1 - 0.006 16.4 2.0 0.012 15.5 2.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4897) DUF2853 PF11015.8 GBG85191.1 - 0.075 13.7 1.4 0.22 12.2 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2853) Glyco_hydro_77 PF02446.17 GBG85191.1 - 0.17 10.7 0.9 0.25 10.2 0.7 1.3 1 1 0 1 1 1 0 4-alpha-glucanotransferase DUF148 PF02520.17 GBG85191.1 - 0.24 11.5 6.3 0.15 12.2 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 TMPIT PF07851.13 GBG85191.1 - 0.28 10.4 5.1 3.1 6.9 2.3 2.0 2 0 0 2 2 2 0 TMPIT-like protein PCRF PF03462.18 GBG85191.1 - 1.4 8.8 9.5 1.9 8.3 5.9 2.1 2 0 0 2 2 2 0 PCRF domain YtxH PF12732.7 GBG85191.1 - 1.9 9.1 6.3 61 4.2 6.3 2.9 1 1 0 1 1 1 0 YtxH-like protein DUF4795 PF16043.5 GBG85191.1 - 3.8 7.1 13.6 2.4e+02 1.2 13.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Plavaka PF18759.1 GBG85192.1 - 1.7e-25 89.9 0.2 2.9e-25 89.2 0.2 1.3 1 0 0 1 1 1 1 Plavaka transposase Histone PF00125.24 GBG85192.1 - 6.8e-25 87.9 0.2 2.2e-24 86.3 0.2 2.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 LCM PF04072.14 GBG85192.1 - 0.021 14.8 0.8 0.11 12.5 0.1 2.3 2 0 0 2 2 2 0 Leucine carboxyl methyltransferase TFB6 PF17110.5 GBG85193.1 - 0.06 13.1 6.6 0.073 12.8 6.6 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 GBG85193.1 - 2 6.6 15.7 1.9 6.7 15.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG85193.1 - 5.1 5.2 22.2 5.5 5.1 22.2 1.0 1 0 0 1 1 1 0 Nop14-like family PB1 PF00564.24 GBG85194.1 - 0.0011 18.9 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain SARAF PF06682.12 GBG85195.1 - 0.0053 16.5 1.6 0.016 14.9 0.6 2.1 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis TraG_N PF07916.11 GBG85195.1 - 0.017 14.0 12.9 0.025 13.5 12.9 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF1180 PF06679.12 GBG85195.1 - 0.34 11.3 1.4 0.39 11.1 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Orf78 PF06024.12 GBG85195.1 - 2.6 8.4 6.9 13 6.1 6.9 2.0 1 1 0 1 1 1 0 Orf78 (ac78) DUF2457 PF10446.9 GBG85195.1 - 4.8 6.2 6.7 5.8 5.9 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) 2OG-FeII_Oxy_3 PF13640.6 GBG85197.1 - 5e-21 75.4 0.0 7.9e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GBG85197.1 - 8.6e-09 35.8 0.0 1.2e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LpxK PF02606.14 GBG85199.1 - 1.3e-57 195.4 0.5 3.3e-24 85.6 0.6 3.5 3 1 0 3 3 3 3 Tetraacyldisaccharide-1-P 4'-kinase AC_N PF16214.5 GBG85199.1 - 3 6.9 5.2 5.1 6.1 5.2 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Med30 PF11315.8 GBG85200.1 - 2.3e-06 27.9 4.4 0.0032 17.7 3.0 2.3 2 1 0 2 2 2 2 Mediator complex subunit 30 SKA2 PF16740.5 GBG85200.1 - 0.0058 16.4 1.6 0.013 15.2 1.1 1.7 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 FlgN PF05130.12 GBG85200.1 - 0.016 15.8 3.9 0.027 15.0 3.1 1.7 2 0 0 2 2 2 0 FlgN protein DUF812 PF05667.11 GBG85200.1 - 0.074 11.9 2.0 0.1 11.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2992 PF11208.8 GBG85200.1 - 0.15 12.3 0.9 0.22 11.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Rx_N PF18052.1 GBG85200.1 - 0.25 11.7 4.6 0.56 10.5 2.8 2.0 2 0 0 2 2 2 0 Rx N-terminal domain NBP1 PF08537.10 GBG85200.1 - 0.57 9.5 5.1 0.79 9.1 5.1 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Plasmodium_Vir PF05795.11 GBG85201.1 - 2.3 7.5 8.8 3.2 7.1 8.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC27 PF09507.10 GBG85201.1 - 5.3 6.3 31.0 6.4 6.0 31.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4187 PF13821.6 GBG85202.1 - 0.0011 18.7 0.2 0.0027 17.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF2781 PF10914.8 GBG85202.1 - 0.14 12.6 0.4 0.34 11.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) SlyX PF04102.12 GBG85203.1 - 0.0026 18.3 3.1 0.0026 18.3 3.1 3.2 2 2 1 3 3 3 1 SlyX Acid_PPase PF12689.7 GBG85203.1 - 0.086 12.7 1.8 0.16 11.8 0.2 2.0 2 0 0 2 2 2 0 Acid Phosphatase RVT_1 PF00078.27 GBG85204.1 - 2.4e-31 109.0 0.1 4.4e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85204.1 - 6.7e-27 93.5 0.0 8e-26 90.0 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85204.1 - 8.4e-24 83.9 0.2 3e-22 78.9 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG85204.1 - 0.012 15.9 1.9 0.11 12.8 0.2 3.3 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG85205.1 - 2.1e-21 76.1 0.0 3.5e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85205.1 - 3.9e-19 68.6 0.0 6.6e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85205.1 - 1.8e-17 63.2 1.2 1.4e-16 60.3 0.3 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG85205.1 - 2.7e-10 40.5 0.0 5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85205.1 - 0.0022 18.2 0.1 0.0068 16.6 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Integrin_b_cyt PF08725.11 GBG85205.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RVT_1 PF00078.27 GBG85206.1 - 1.1e-14 54.5 0.0 2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG85206.1 - 5.3e-06 26.6 0.0 3.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG85206.1 - 0.0049 16.7 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Mucin PF01456.17 GBG85207.1 - 0.0046 17.0 30.5 0.0084 16.1 30.5 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.12 GBG85207.1 - 0.64 7.9 22.9 0.82 7.6 22.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MID_MedPIWI PF18296.1 GBG85207.1 - 2.3 8.0 7.0 4.8 6.9 7.1 1.4 1 1 0 1 1 1 0 MID domain of medPIWI Tir_receptor_C PF07489.11 GBG85207.1 - 3.2 7.7 25.4 4.5 7.2 25.4 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus BAF1_ABF1 PF04684.13 GBG85207.1 - 3.2 6.7 21.6 4.3 6.3 21.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 GBG85207.1 - 4.9 5.8 7.2 6.4 5.4 7.2 1.1 1 0 0 1 1 1 0 Presenilin HNF-1_N PF04814.13 GBG85207.1 - 6.5 7.3 10.6 10 6.7 10.6 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus KCT2 PF17818.1 GBG85207.1 - 8.1 6.5 15.9 12 5.9 15.9 1.3 1 0 0 1 1 1 0 Keratinocyte-associated gene product zf-CCHC PF00098.23 GBG85208.1 - 2.7e-07 30.4 5.4 2.7e-07 30.4 5.4 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG85208.1 - 0.024 14.3 2.5 0.057 13.1 2.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG85208.1 - 0.28 11.1 7.0 0.17 11.7 2.7 2.4 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG85214.1 - 4.7e-25 88.4 0.1 7.5e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85214.1 - 1.8e-15 56.8 0.0 1.6e-12 47.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85214.1 - 3.1e-12 46.7 0.1 1.4e-11 44.6 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG85214.1 - 1e-06 29.0 0.0 2.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4360 PF14273.6 GBG85215.1 - 1e-36 126.5 0.0 1.2e-36 126.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG85217.1 - 5.1e-32 111.2 0.0 6.1e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF3839 PF12943.7 GBG85217.1 - 0.3 10.5 0.1 0.43 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) DUF4360 PF14273.6 GBG85219.1 - 4.6e-36 124.3 0.0 5.3e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NPCBM_assoc PF10633.9 GBG85219.1 - 0.12 12.6 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase RVT_1 PF00078.27 GBG85221.1 - 4.1e-26 91.9 0.1 7e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG85221.1 - 7.7e-15 54.8 0.1 2e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85221.1 - 6.4e-09 36.0 0.0 1.9e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85221.1 - 0.00016 21.8 0.2 0.00039 20.6 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG85222.1 - 1.9e-12 47.1 0.1 4e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85222.1 - 2e-06 28.0 0.0 3.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain SICA_C PF12879.7 GBG85222.1 - 0.015 15.3 9.4 0.22 11.6 2.8 2.4 1 1 1 2 2 2 0 SICA C-terminal inner membrane domain zf-H2C2 PF09337.10 GBG85222.1 - 0.026 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC_5 PF14787.6 GBG85222.1 - 0.044 13.5 0.2 0.093 12.5 0.2 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG85223.1 - 0.034 14.2 1.9 0.084 13.0 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG85223.1 - 0.12 12.1 0.2 0.26 11.0 0.2 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Integrase_H2C2 PF17921.1 GBG85224.1 - 5.6e-13 48.8 0.1 1.2e-12 47.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85224.1 - 9.5e-07 29.0 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG85224.1 - 0.00013 22.5 0.0 0.00036 21.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85224.1 - 0.0023 18.6 0.0 0.0063 17.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85224.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85224.1 - 0.11 12.3 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease Asn_synthase PF00733.21 GBG85225.1 - 5.5e-94 315.7 1.7 6.6e-56 190.5 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 GBG85225.1 - 2.5e-44 150.1 0.0 3.9e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GBG85225.1 - 1.1e-33 116.3 0.0 1.8e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GBG85225.1 - 6e-13 48.8 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 GBG85225.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PC-Esterase PF13839.6 GBG85228.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Aminoglyc_resit PF10706.9 GBG85230.1 - 6.4e-06 26.0 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Aminoglycoside-2''-adenylyltransferase Beta_helix PF13229.6 GBG85232.1 - 0.00074 19.4 0.6 0.00074 19.4 0.6 2.0 2 0 0 2 2 2 1 Right handed beta helix region WDCP PF15390.6 GBG85236.1 - 0.54 8.6 2.9 0.84 7.9 2.9 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family zf-CCHC PF00098.23 GBG85237.1 - 4.9e-07 29.5 2.2 1e-06 28.5 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG85237.1 - 0.0061 16.2 0.8 0.012 15.3 0.8 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG85237.1 - 0.032 14.0 0.7 0.085 12.6 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle GREB1 PF15782.5 GBG85237.1 - 0.68 7.0 3.0 0.85 6.7 3.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PDCD2_C PF04194.13 GBG85238.1 - 0.18 11.9 1.5 0.36 10.9 1.5 1.5 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain SMC_N PF02463.19 GBG85239.1 - 2.4e-34 118.7 10.0 1.5e-33 116.1 10.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GBG85239.1 - 2.7e-15 57.4 21.2 9.7e-14 52.3 21.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 GBG85239.1 - 1e-11 45.2 8.8 1.3e-11 44.8 8.8 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 GBG85239.1 - 3.3e-06 27.1 0.2 1.4e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GBG85239.1 - 0.0062 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 GBG85239.1 - 0.014 14.8 0.4 0.038 13.3 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.27 GBG85239.1 - 0.49 10.9 7.4 36 4.9 7.4 2.7 1 1 0 1 1 1 0 ABC transporter DUF87 PF01935.17 GBG85239.1 - 0.5 10.4 0.0 0.5 10.4 0.0 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain KELK PF15796.5 GBG85239.1 - 1.9 9.0 27.2 5.9 7.4 8.1 3.3 1 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FRG1 PF06229.12 GBG85239.1 - 2.9 7.6 13.8 1.6 8.4 11.1 1.9 1 1 1 2 2 2 0 FRG1-like domain CRA PF06589.11 GBG85239.1 - 8 6.6 12.7 9.7 6.3 1.2 3.0 2 1 0 2 2 2 0 Circumsporozoite-related antigen (CRA) SMC_N PF02463.19 GBG85240.1 - 1.2e-30 106.6 2.0 1.7e-30 106.2 2.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GBG85240.1 - 1.8e-26 92.8 0.0 6e-26 91.0 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GBG85240.1 - 5.5e-09 36.2 0.0 1.4e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 GBG85240.1 - 0.00053 19.0 68.2 0.012 14.5 9.5 3.5 2 1 1 3 3 3 3 Spc7 kinetochore protein DUF773 PF05600.12 GBG85240.1 - 0.00099 18.0 6.3 0.00099 18.0 6.3 4.3 2 1 4 6 6 5 1 CDK5 regulatory subunit-associated protein 3 ATG16 PF08614.11 GBG85240.1 - 0.0021 18.4 73.9 0.025 14.8 11.5 4.8 2 1 3 5 5 5 3 Autophagy protein 16 (ATG16) Prominin PF05478.11 GBG85240.1 - 0.0028 15.7 0.3 0.0028 15.7 0.3 3.2 2 1 1 3 3 3 1 Prominin EzrA PF06160.12 GBG85240.1 - 0.0039 15.4 4.9 0.0039 15.4 4.9 3.5 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA DUF3584 PF12128.8 GBG85240.1 - 0.0056 14.3 50.9 0.063 10.8 33.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) UPF0242 PF06785.11 GBG85240.1 - 0.014 15.5 4.7 0.014 15.5 4.7 4.3 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus FlaG PF03646.15 GBG85240.1 - 0.017 15.3 0.7 0.017 15.3 0.7 5.7 3 2 3 7 7 7 0 FlaG protein RWP-RK PF02042.15 GBG85240.1 - 0.1 12.6 0.3 0.35 10.9 0.0 2.1 2 0 0 2 2 1 0 RWP-RK domain DUF948 PF06103.11 GBG85240.1 - 0.27 11.5 20.5 0.42 10.9 2.1 5.5 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) ABC_tran PF00005.27 GBG85240.1 - 0.39 11.2 0.0 0.39 11.2 0.0 4.2 2 1 0 3 3 2 0 ABC transporter Nup54 PF13874.6 GBG85240.1 - 1.3 9.1 48.9 0.47 10.6 6.1 4.4 2 1 2 4 4 4 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 GBG85240.1 - 1.6 9.3 79.5 0.038 14.5 10.3 5.2 2 1 2 4 4 3 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 GBG85240.1 - 2.2 7.7 63.9 0.18 11.3 13.4 3.4 2 1 1 3 3 3 0 Golgin subfamily A member 5 SieB PF14163.6 GBG85240.1 - 2.7 7.5 7.0 0.57 9.7 1.3 2.5 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF3958 PF13125.6 GBG85240.1 - 3 8.1 48.0 0.041 14.1 5.5 4.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3958) HAUS5 PF14817.6 GBG85240.1 - 3.8 6.2 47.6 0.3 9.8 21.5 3.4 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 5 DUF3450 PF11932.8 GBG85240.1 - 5 6.4 54.5 0.053 12.8 2.7 4.3 2 1 1 4 4 4 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 GBG85240.1 - 6.3 6.8 25.0 36 4.4 6.7 4.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 GBG85240.1 - 9.2 5.5 49.7 1.1 8.5 0.9 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4407) ELH PF02323.15 GBG85241.1 - 0.043 13.2 5.4 0.046 13.1 5.4 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor DUF2721 PF11026.8 GBG85241.1 - 5.1 7.0 8.9 5.5 6.9 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) RT_RNaseH_2 PF17919.1 GBG85242.1 - 6.8e-34 115.9 0.0 1.1e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85242.1 - 1.7e-21 76.4 0.0 3.2e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG85242.1 - 1.2e-07 31.4 0.8 2.8e-07 30.3 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG85242.1 - 0.00052 19.8 3.3 0.0011 18.7 3.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Sulfate_transp PF00916.20 GBG85243.1 - 6.7e-76 255.5 5.7 9.7e-76 255.0 5.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GBG85243.1 - 1.4e-14 53.8 0.1 2.7e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 STAS domain SseC PF04888.12 GBG85243.1 - 0.028 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family AzlD PF05437.12 GBG85243.1 - 0.16 12.2 0.2 0.16 12.2 0.2 3.0 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) STAS PF01740.21 GBG85244.1 - 1e-22 80.0 0.0 1.5e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 STAS domain RCC_reductase PF06405.11 GBG85245.1 - 2.3e-29 102.4 0.0 3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) RCC_reductase PF06405.11 GBG85246.1 - 2.1e-28 99.2 0.0 3.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) YL1 PF05764.13 GBG85246.1 - 2.3e-06 27.9 16.4 4.2e-06 27.1 16.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 GBG85246.1 - 0.0089 15.5 38.3 0.014 14.9 38.3 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG85246.1 - 0.0091 14.3 36.4 0.013 13.8 36.4 1.1 1 0 0 1 1 1 1 Nop14-like family Tim54 PF11711.8 GBG85246.1 - 0.024 13.5 2.7 0.036 12.9 2.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MDM1 PF15501.6 GBG85246.1 - 0.14 11.3 11.3 0.2 10.7 11.3 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 CDC45 PF02724.14 GBG85246.1 - 0.24 9.7 29.1 0.35 9.1 29.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 GBG85246.1 - 6.9 6.7 26.0 11 6.0 26.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Retrotrans_gag PF03732.17 GBG85247.1 - 0.0007 19.8 0.6 0.0017 18.6 0.1 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Nucleoporin_C PF03177.14 GBG85248.1 - 2.6e-09 36.4 0.1 5.3e-08 32.1 0.0 2.4 1 1 1 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 GBG85248.1 - 0.00038 19.3 0.0 0.035 12.9 0.0 2.1 2 0 0 2 2 2 2 Nup133 N terminal like AP1AR PF15745.5 GBG85249.1 - 0.018 14.7 15.5 0.03 14.0 15.5 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein SCIMP PF15050.6 GBG85249.1 - 0.21 12.1 2.7 0.15 12.6 0.5 1.8 1 1 1 2 2 2 0 SCIMP protein DUF5102 PF17104.5 GBG85249.1 - 0.26 11.3 11.5 0.33 10.9 10.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5102) Hid1 PF12722.7 GBG85249.1 - 1.6 6.8 10.8 2 6.4 10.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LicD PF04991.13 GBG85249.1 - 4 7.5 7.2 7.1 6.7 7.2 1.4 1 0 0 1 1 1 0 LicD family NARP1 PF12569.8 GBG85249.1 - 4 6.2 19.5 6.2 5.6 19.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 XRN_M PF17846.1 GBG85249.1 - 7.4 5.4 10.2 11 4.8 10.2 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Branch PF02485.21 GBG85251.1 - 2.6e-43 148.3 0.0 3.5e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF3138 PF11336.8 GBG85252.1 - 0.042 12.5 1.0 0.068 11.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TssO PF17561.2 GBG85252.1 - 6.6 6.8 12.7 0.33 11.0 6.9 1.7 2 1 0 2 2 2 0 Type VI secretion system, TssO DUF755 PF05501.11 GBG85252.1 - 9.2 6.6 16.2 4.8 7.5 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Asp_protease_2 PF13650.6 GBG85253.1 - 4.5e-06 27.2 0.0 0.00082 20.0 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85253.1 - 4.1e-05 24.1 0.2 0.00053 20.5 0.0 2.6 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG85253.1 - 0.039 13.7 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4968 PF16338.5 GBG85253.1 - 0.083 13.2 0.0 2.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4968) Branch PF02485.21 GBG85254.1 - 1.1e-42 146.3 0.1 1.5e-42 145.8 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme RT_RNaseH_2 PF17919.1 GBG85255.1 - 1.1e-63 211.5 0.0 2.6e-34 117.3 0.0 3.5 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85255.1 - 4.3e-59 199.7 1.3 7.1e-30 104.2 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85255.1 - 5.2e-50 168.1 0.0 1.4e-30 105.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85255.1 - 1.2e-18 67.0 0.2 1.2e-18 67.0 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG85255.1 - 7.3e-13 48.8 0.1 4.8e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG85255.1 - 5.2e-05 23.7 0.0 0.00013 22.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG85255.1 - 0.00025 20.8 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG85255.1 - 0.0038 17.0 0.1 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG85255.1 - 0.0091 16.6 0.0 0.022 15.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG85256.1 - 1e-31 110.2 0.0 1.6e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85256.1 - 2.8e-18 65.8 0.0 7.3e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85256.1 - 1.6e-08 34.8 0.0 3.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rRNA_proc-arch PF13234.6 GBG85257.1 - 0.006 16.6 1.0 2.2 8.1 0.1 2.4 2 0 0 2 2 2 2 rRNA-processing arch domain Cas_Csy1 PF09611.10 GBG85257.1 - 0.032 13.3 2.8 0.39 9.7 0.2 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy1) HAUS6_N PF14661.6 GBG85257.1 - 0.093 12.3 4.3 5 6.6 0.2 2.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Peptidase_S64 PF08192.11 GBG85257.1 - 0.1 11.1 4.1 0.091 11.2 1.6 1.8 2 0 0 2 2 2 0 Peptidase family S64 FliS_cochap PF16522.5 GBG85257.1 - 0.11 12.5 1.1 13 5.7 0.1 2.7 2 2 0 2 2 2 0 Flagellar FLiS export co-chaperone, HP1076 RAP1 PF07218.11 GBG85257.1 - 0.11 10.8 4.1 0.15 10.3 3.2 1.6 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Retrotrans_gag PF03732.17 GBG85257.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.3 3 0 0 3 3 3 0 Retrotransposon gag protein CSF-1 PF05337.11 GBG85257.1 - 0.16 12.1 0.2 8.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) BDV_G PF06208.11 GBG85257.1 - 0.39 9.8 1.7 2.7 7.1 0.0 2.0 2 0 0 2 2 2 0 Borna disease virus G protein Noelin-1 PF12308.8 GBG85257.1 - 0.7 9.9 11.0 2.8 8.0 0.6 3.4 4 0 0 4 4 3 0 Neurogenesis glycoprotein Miga PF10265.9 GBG85257.1 - 0.92 8.4 7.7 0.88 8.5 4.8 1.9 2 0 0 2 2 2 0 Mitoguardin TMF_TATA_bd PF12325.8 GBG85257.1 - 1.2 9.4 12.7 2.2 8.6 2.4 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Trans_reg_C PF00486.28 GBG85257.1 - 1.4 9.1 4.3 31 4.8 0.2 2.9 3 0 0 3 3 2 0 Transcriptional regulatory protein, C terminal DUF4168 PF13767.6 GBG85257.1 - 1.7 9.9 8.9 15 6.8 0.2 3.8 4 1 0 4 4 3 0 Domain of unknown function (DUF4168) FAM199X PF15814.5 GBG85257.1 - 2.3 7.2 9.4 6.4 5.7 9.4 1.7 1 0 0 1 1 1 0 Protein family FAM199X HHH_9 PF17674.1 GBG85257.1 - 4.8 8.2 12.2 1.1e+02 3.8 0.8 4.6 2 2 2 4 4 4 0 HHH domain TraF PF13728.6 GBG85257.1 - 9.3 6.0 8.4 5.4 6.8 1.8 2.5 2 0 0 2 2 2 0 F plasmid transfer operon protein zf-RING_2 PF13639.6 GBG85258.1 - 5e-07 29.9 4.3 5e-07 29.9 4.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 GBG85258.1 - 1.2e-06 28.1 6.3 2.5e-06 27.1 6.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GBG85258.1 - 7.6e-06 25.7 1.5 1.8e-05 24.5 1.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG85258.1 - 1.4e-05 25.3 2.9 3.7e-05 23.9 2.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GBG85258.1 - 8e-05 22.4 4.7 0.00021 21.0 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GBG85258.1 - 0.00056 20.0 0.9 0.0014 18.8 0.9 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 GBG85258.1 - 0.0025 17.8 1.8 0.0057 16.7 1.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG85258.1 - 0.0045 16.9 2.4 0.012 15.6 2.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GBG85258.1 - 0.012 15.6 2.5 0.012 15.6 2.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 GBG85258.1 - 0.021 14.7 3.0 0.058 13.3 3.0 1.7 1 0 0 1 1 1 0 PHD-finger Myb_Cef PF11831.8 GBG85259.1 - 5.7e-45 153.7 0.1 5.7e-45 153.7 0.1 5.5 5 1 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 GBG85259.1 - 1.6e-21 76.2 4.8 6.2e-11 42.3 1.5 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG85259.1 - 3.2e-21 75.3 4.0 1.3e-12 47.7 2.8 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 GBG85259.1 - 0.053 13.6 1.3 1.4 9.1 0.1 3.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pkinase PF00069.25 GBG85260.1 - 3.2e-37 128.3 0.0 5.5e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG85260.1 - 1.6e-33 116.1 0.0 3e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG85260.1 - 0.01 15.2 0.0 0.09 12.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Copper-bind PF00127.20 GBG85260.1 - 0.019 15.4 2.6 0.09 13.2 0.0 3.2 3 0 0 3 3 3 0 Copper binding proteins, plastocyanin/azurin family RCC_reductase PF06405.11 GBG85261.1 - 2.2e-27 95.9 0.0 4.8e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) DUF659 PF04937.15 GBG85261.1 - 8.7e-15 54.9 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CDC45 PF02724.14 GBG85263.1 - 0.5 8.6 13.4 0.62 8.3 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG85263.1 - 1.2 8.5 19.8 1.6 8.1 19.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG85263.1 - 3.3 5.8 18.0 4.1 5.5 18.0 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG85263.1 - 4.7 5.9 7.0 5.4 5.7 7.0 1.1 1 0 0 1 1 1 0 Presenilin Lamprin PF06403.11 GBG85265.1 - 3.9 7.4 12.5 7.4 6.5 12.5 1.4 1 0 0 1 1 1 0 Lamprin PA26 PF04636.13 GBG85268.1 - 0.46 9.3 9.6 0.63 8.9 9.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3629 PF12302.8 GBG85268.1 - 4.2 6.7 8.8 7.5 5.9 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) RT_RNaseH PF17917.1 GBG85269.1 - 4e-21 75.3 0.0 2.9e-20 72.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85269.1 - 5.9e-21 74.4 0.0 1.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85269.1 - 5.2e-12 45.7 0.3 1.2e-11 44.5 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85269.1 - 1.8e-10 41.0 0.0 4.5e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG85269.1 - 9.5e-09 35.1 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Drf_GBD PF06371.13 GBG85269.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Jnk-SapK_ap_N PF09744.9 GBG85269.1 - 2.7 8.2 11.6 0.034 14.4 3.2 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 zf-CCHC PF00098.23 GBG85270.1 - 0.2 11.8 1.7 0.39 10.9 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle CENP-N PF05238.13 GBG85270.1 - 1.3 8.2 5.4 2.5 7.3 1.6 2.4 2 1 0 2 2 2 0 Kinetochore protein CHL4 like Dimer_Tnp_hAT PF05699.14 GBG85271.1 - 0.0003 20.5 0.0 0.00092 19.0 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.17 GBG85275.1 - 0.0069 16.6 0.2 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG85275.1 - 0.024 14.6 1.4 0.045 13.7 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG85275.1 - 0.67 10.1 4.0 1.1 9.5 4.0 1.3 1 0 0 1 1 1 0 Zinc knuckle RE_BstXI PF09552.10 GBG85276.1 - 0.11 11.7 1.7 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 BstXI restriction endonuclease LsmAD PF06741.13 GBG85276.1 - 5.6 7.6 6.0 3.4 8.3 2.9 2.3 1 1 1 2 2 2 0 LsmAD domain Methyltransf_16 PF10294.9 GBG85278.1 - 3e-16 59.6 0.0 1.4e-09 38.0 0.0 2.6 2 0 0 2 2 2 2 Lysine methyltransferase Presenilin PF01080.17 GBG85278.1 - 2.4e-05 23.3 24.7 3.6e-05 22.7 24.7 1.2 1 0 0 1 1 1 1 Presenilin CDC45 PF02724.14 GBG85278.1 - 0.00026 19.5 18.6 0.00031 19.2 18.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Velvet PF11754.8 GBG85278.1 - 0.0024 17.9 20.0 0.0038 17.2 20.0 1.3 1 0 0 1 1 1 1 Velvet factor TFIIA PF03153.13 GBG85278.1 - 0.0027 17.8 60.3 0.0061 16.6 60.3 1.6 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 GBG85278.1 - 0.0041 17.0 32.9 0.0062 16.4 32.9 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 GBG85278.1 - 0.032 12.2 24.6 0.044 11.7 24.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CBP_BcsG PF11658.8 GBG85278.1 - 0.038 12.4 11.8 0.062 11.7 11.8 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Membralin PF09746.9 GBG85278.1 - 0.039 13.0 13.9 0.052 12.6 13.9 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF2052 PF09747.9 GBG85278.1 - 0.052 13.7 31.2 0.088 12.9 31.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ndc1_Nup PF09531.10 GBG85278.1 - 0.054 12.2 17.0 0.066 11.9 17.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2126 PF09899.9 GBG85278.1 - 0.09 10.8 16.5 0.14 10.2 16.5 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF4045 PF13254.6 GBG85278.1 - 0.098 12.3 23.2 0.14 11.8 23.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) LMBR1 PF04791.16 GBG85278.1 - 0.16 10.9 11.1 0.2 10.5 11.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.9 GBG85278.1 - 0.16 10.2 45.2 0.22 9.8 45.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 GBG85278.1 - 0.38 9.7 31.2 0.51 9.3 31.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 GBG85278.1 - 0.44 10.1 34.1 0.62 9.6 34.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCSAP PF15748.5 GBG85278.1 - 0.45 10.6 34.7 0.77 9.9 34.7 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MMR1 PF08505.10 GBG85278.1 - 0.56 10.4 31.4 1.1 9.4 31.4 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GREB1 PF15782.5 GBG85278.1 - 0.62 7.1 29.2 0.78 6.8 29.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM60A PF15396.6 GBG85278.1 - 0.83 9.6 25.5 1.3 8.9 25.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A XRN_M PF17846.1 GBG85278.1 - 0.84 8.5 23.5 1.2 8.1 23.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Paf1 PF03985.13 GBG85278.1 - 0.95 8.4 33.2 1.4 7.8 33.2 1.3 1 0 0 1 1 1 0 Paf1 ALMT PF11744.8 GBG85278.1 - 1.2 7.9 28.7 1.7 7.4 28.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF913 PF06025.12 GBG85278.1 - 1.3 7.9 17.3 2.2 7.1 17.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 GBG85278.1 - 1.5 7.5 31.1 2.1 7.1 31.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Otopetrin PF03189.13 GBG85278.1 - 1.6 7.4 16.2 2.4 6.9 16.2 1.3 1 0 0 1 1 1 0 Otopetrin Zip PF02535.22 GBG85278.1 - 1.6 7.8 15.5 2.5 7.2 15.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 GBG85278.1 - 1.8 6.6 29.7 2.3 6.2 29.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.6 GBG85278.1 - 1.9 7.1 25.9 2.8 6.6 25.9 1.2 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.12 GBG85278.1 - 2.1 8.5 25.9 3.4 7.9 25.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PNISR PF15996.5 GBG85278.1 - 2.7 8.2 39.0 4.5 7.5 39.0 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF1846 PF08903.11 GBG85278.1 - 2.8 6.4 10.7 4.2 5.8 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Hamartin PF04388.12 GBG85278.1 - 2.9 6.5 31.6 4 6.0 31.6 1.1 1 0 0 1 1 1 0 Hamartin protein SAPS PF04499.15 GBG85278.1 - 3 6.5 25.5 4.1 6.1 25.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dapper PF15268.6 GBG85278.1 - 3.5 6.4 36.4 5 5.8 36.4 1.1 1 0 0 1 1 1 0 Dapper SID-1_RNA_chan PF13965.6 GBG85278.1 - 4.1 5.7 13.7 5.7 5.2 13.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MCM_bind PF09739.9 GBG85278.1 - 4.2 5.7 29.6 5.7 5.3 29.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CRT10 PF08728.10 GBG85278.1 - 4.4 5.4 15.4 5.5 5.0 15.4 1.1 1 0 0 1 1 1 0 CRT10 UPF0564 PF10595.9 GBG85278.1 - 6.2 5.8 49.1 9 5.2 49.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Gti1_Pac2 PF09729.9 GBG85278.1 - 6.2 6.9 27.1 14 5.7 27.1 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family PA26 PF04636.13 GBG85278.1 - 8.9 5.1 24.6 12 4.6 24.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Radical_SAM_N PF08497.10 GBG85278.1 - 8.9 5.4 13.0 13 4.9 13.0 1.3 1 0 0 1 1 1 0 Radical SAM N-terminal Exonuc_VII_L PF02601.15 GBG85278.1 - 9.6 5.7 29.8 14 5.1 29.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RT_RNaseH_2 PF17919.1 GBG85279.1 - 2e-21 75.9 0.0 3.8e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85279.1 - 2.5e-21 75.9 0.0 8.1e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG85279.1 - 0.0016 19.0 0.0 0.0038 17.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85279.1 - 0.0034 18.0 0.0 0.0075 16.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85279.1 - 0.0081 16.5 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG85279.1 - 0.047 13.2 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG85279.1 - 0.11 12.2 0.2 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG85280.1 - 2.4e-07 31.2 0.1 6.2e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85280.1 - 8.7e-05 23.1 0.1 0.00019 22.0 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85280.1 - 0.00054 19.8 0.1 0.00094 19.0 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85280.1 - 0.0051 16.6 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG85280.1 - 0.092 12.9 3.0 0.2 11.8 3.0 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG85282.1 - 1.8e-26 93.0 0.0 2.9e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG85282.1 - 4.2e-05 24.0 0.0 9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85282.1 - 0.00018 22.1 0.0 0.00039 21.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG85282.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG85282.1 - 0.17 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DDE_Tnp_4 PF13359.6 GBG85283.1 - 5.1e-37 127.0 0.0 7.5e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85283.1 - 2.3e-12 47.0 0.0 4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein HTH_Tnp_4 PF13613.6 GBG85283.1 - 0.0014 18.3 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GBG85283.1 - 0.027 14.1 0.1 0.22 11.1 0.1 2.3 1 1 0 1 1 1 0 Transposase DDE domain OHCU_decarbox PF09349.10 GBG85286.1 - 0.0049 17.4 1.3 0.01 16.3 0.6 1.9 1 1 0 1 1 1 1 OHCU decarboxylase Retrotrans_gag PF03732.17 GBG85286.1 - 0.0081 16.4 3.3 0.88 9.9 0.0 3.4 3 0 0 3 3 3 2 Retrotransposon gag protein KapB PF08810.10 GBG85286.1 - 0.011 15.9 0.5 4.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Kinase associated protein B TFIIA PF03153.13 GBG85286.1 - 4.3 7.2 14.3 6.3 6.7 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RVT_1 PF00078.27 GBG85287.1 - 3.8e-31 108.3 0.1 5.4e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDH1_2_SANT_HL1 PF18375.1 GBG85287.1 - 0.058 14.1 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 RT_RNaseH_2 PF17919.1 GBG85288.1 - 9.9e-29 99.3 0.0 1.7e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85288.1 - 5.1e-26 91.0 0.0 1.1e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85289.1 - 1.1e-25 90.4 0.1 1.8e-25 89.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85289.1 - 4.3e-25 88.0 0.0 9.4e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85289.1 - 8.5e-25 86.7 0.0 4.3e-24 84.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85289.1 - 1.9e-18 66.3 0.4 6.7e-18 64.5 0.4 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85291.1 - 1e-35 123.3 0.1 1.9e-35 122.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85291.1 - 1.1e-27 95.9 0.0 3.6e-27 94.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85291.1 - 2.1e-26 92.2 0.0 4.9e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gpUL132 PF11359.8 GBG85291.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 RNA_pol_3_Rpc31 PF11705.8 GBG85291.1 - 3.7 7.7 19.3 1.6 9.0 15.9 2.2 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Presenilin PF01080.17 GBG85291.1 - 7.2 5.3 6.8 12 4.5 6.8 1.3 1 0 0 1 1 1 0 Presenilin DUF659 PF04937.15 GBG85292.1 - 5.9e-31 107.4 0.0 9.7e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG85292.1 - 1.8e-09 37.2 0.1 1.3e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.17 GBG85294.1 - 0.00012 22.3 5.5 0.013 15.7 0.0 4.0 4 1 0 4 4 4 2 Retrotransposon gag protein WDCP PF15390.6 GBG85294.1 - 0.99 7.7 4.0 1.4 7.2 4.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family AIF-MLS PF14962.6 GBG85294.1 - 5.2 7.0 8.3 12 5.7 8.3 1.6 1 0 0 1 1 1 0 Mitochondria Localisation Sequence ERM PF00769.19 GBG85294.1 - 9.1 6.0 24.2 21 4.8 24.2 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family RT_RNaseH_2 PF17919.1 GBG85295.1 - 5.4e-25 87.3 0.0 1.9e-24 85.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85295.1 - 1.7e-21 76.8 0.3 1.1e-20 74.1 0.1 2.0 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85295.1 - 8e-21 74.3 0.0 2.4e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85295.1 - 2.7e-15 56.2 0.2 5.5e-15 55.2 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG85295.1 - 0.0013 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG85295.1 - 0.0017 19.0 0.0 0.0039 17.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85295.1 - 0.004 16.9 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG85295.1 - 0.0046 17.5 0.0 0.0096 16.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG85296.1 - 2.1e-11 43.8 0.0 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85296.1 - 4.5e-10 39.4 0.0 7.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG85296.1 - 2.7e-06 27.6 0.1 7e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain EMP70 PF02990.16 GBG85298.1 - 8.1e-171 569.2 14.4 1e-170 568.9 14.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Integrase_H2C2 PF17921.1 GBG85300.1 - 5.7e-15 55.2 0.1 1.7e-14 53.7 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85300.1 - 1.1e-08 34.8 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG85300.1 - 9.4e-07 29.0 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85300.1 - 0.0017 18.5 0.0 0.0045 17.2 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG85301.1 - 2.9e-16 59.5 0.0 4.3e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85301.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG85302.1 - 2.5e-06 27.8 1.2 5e-06 26.8 1.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TetR_C_24 PF17932.1 GBG85302.1 - 0.041 14.1 0.1 0.093 13.0 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FUSC PF04632.12 GBG85302.1 - 0.062 11.8 0.1 0.11 11.0 0.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family NIR_SIR_ferr PF03460.17 GBG85302.1 - 0.14 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain Phage_HK97_TLTM PF06120.11 GBG85302.1 - 0.14 11.3 0.1 0.3 10.2 0.1 1.5 1 1 0 1 1 1 0 Tail length tape measure protein ZapB PF06005.12 GBG85302.1 - 0.18 12.2 0.7 0.58 10.6 0.7 1.8 1 1 0 1 1 1 0 Cell division protein ZapB Dapper PF15268.6 GBG85303.1 - 2.7 6.7 10.2 3.1 6.5 10.2 1.0 1 0 0 1 1 1 0 Dapper SDA1 PF05285.12 GBG85303.1 - 2.8 7.3 17.4 4 6.8 17.4 1.3 1 0 0 1 1 1 0 SDA1 Neur_chan_memb PF02932.16 GBG85303.1 - 3.3 7.7 4.7 3.9 7.5 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Utp14 PF04615.13 GBG85303.1 - 3.7 6.0 17.8 5 5.6 17.8 1.2 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 GBG85303.1 - 5.4 5.9 15.0 6.9 5.6 15.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 GBG85303.1 - 7.4 5.0 22.5 8.9 4.7 22.5 1.1 1 0 0 1 1 1 0 Macoilin family PNISR PF15996.5 GBG85303.1 - 8.1 6.7 11.2 11 6.2 11.2 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Nop14 PF04147.12 GBG85303.1 - 8.2 4.5 19.5 9.2 4.3 19.5 1.0 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG85303.1 - 9.5 5.7 15.2 12 5.4 15.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-3CxxC PF13695.6 GBG85305.1 - 0.33 11.5 4.8 0.64 10.5 0.4 2.5 2 0 0 2 2 2 0 Zinc-binding domain VQ PF05678.14 GBG85306.1 - 6.2e-08 32.0 0.0 7e-07 28.6 0.0 3.0 1 0 0 1 1 1 1 VQ motif SAPS PF04499.15 GBG85306.1 - 5.6 5.6 23.0 1 8.1 19.0 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein FSA_C PF10479.9 GBG85307.1 - 0.62 8.1 7.7 0.85 7.7 7.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RT_RNaseH PF17917.1 GBG85308.1 - 1.5e-30 105.6 0.0 3.3e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85308.1 - 1.5e-29 101.9 0.0 3.6e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85308.1 - 8.6e-11 41.8 0.1 2.5e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG85308.1 - 0.052 13.2 0.0 0.052 13.2 0.0 2.7 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase REV PF00424.18 GBG85308.1 - 0.13 12.3 0.2 0.13 12.3 0.2 1.8 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) zf-C2H2_4 PF13894.6 GBG85309.1 - 1.1e-12 47.6 14.9 0.0079 16.9 1.2 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 GBG85309.1 - 1.6e-09 37.7 16.3 0.062 13.8 3.1 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GBG85309.1 - 4.9e-09 36.2 0.6 0.0029 17.8 0.3 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 GBG85309.1 - 1.9e-05 24.9 9.2 0.014 15.6 0.1 4.1 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 GBG85309.1 - 0.00014 22.1 3.5 0.82 10.1 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GBG85309.1 - 0.00078 19.4 15.3 0.043 13.8 2.2 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 GBG85309.1 - 0.034 14.8 2.9 6.3 7.5 0.1 4.3 4 0 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 GBG85309.1 - 0.057 13.2 7.9 0.56 10.0 3.0 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 GBG85309.1 - 0.41 11.0 6.3 0.6 10.5 1.0 3.3 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 GBG85309.1 - 2.2 8.9 20.2 5 7.7 0.1 5.7 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 GBG85309.1 - 3.4 7.7 8.5 20 5.2 0.2 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type TFIIB PF00382.19 GBG85311.1 - 2.3e-34 117.3 5.6 6.3e-21 74.2 0.6 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 GBG85311.1 - 4.3e-17 61.4 0.6 6.9e-17 60.7 0.6 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 GBG85311.1 - 0.00011 22.3 0.3 0.0044 17.1 0.0 2.3 2 1 0 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 GBG85311.1 - 0.00021 21.1 0.1 0.0061 16.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribosomal_S27e PF01667.17 GBG85311.1 - 0.01 15.5 0.7 0.01 15.5 0.7 1.6 2 0 0 2 2 2 0 Ribosomal protein S27 zinc-ribbons_6 PF07191.12 GBG85311.1 - 0.027 14.5 0.6 0.06 13.3 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbons A2L_zn_ribbon PF08792.10 GBG85311.1 - 0.035 13.8 0.9 0.083 12.6 0.9 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 GBG85311.1 - 0.042 13.3 3.1 0.99 8.9 3.1 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Cyclin_C PF02984.19 GBG85311.1 - 0.062 13.4 0.1 2.9 8.0 0.1 2.4 2 1 0 2 2 2 0 Cyclin, C-terminal domain Zn-ribbon_8 PF09723.10 GBG85311.1 - 0.13 12.4 1.3 0.3 11.2 1.3 1.6 1 0 0 1 1 1 0 Zinc ribbon domain SNF5 PF04855.12 GBG85311.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 HHH_9 PF17674.1 GBG85311.1 - 0.15 13.0 0.0 0.44 11.5 0.0 1.9 1 1 0 1 1 1 0 HHH domain DZR PF12773.7 GBG85311.1 - 0.31 11.1 1.7 1.1 9.4 1.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon HTH_38 PF13936.6 GBG85311.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain SecA_SW PF07516.13 GBG85312.1 - 0.54 10.3 3.7 0.73 9.9 0.2 2.6 3 1 0 3 3 3 0 SecA Wing and Scaffold domain SecA_SW PF07516.13 GBG85313.1 - 0.65 10.0 4.0 0.72 9.9 0.2 2.6 3 1 0 3 3 3 0 SecA Wing and Scaffold domain DEK_C PF08766.11 GBG85315.1 - 0.016 15.1 3.4 0.022 14.7 0.0 2.8 3 0 0 3 3 3 0 DEK C terminal domain Chlam_PMP PF02415.17 GBG85316.1 - 0.0027 18.1 33.2 1.6 9.4 1.6 7.3 7 1 0 7 7 7 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NosD PF05048.13 GBG85316.1 - 0.018 14.3 4.8 0.024 13.9 3.2 1.9 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) MT-A70 PF05063.14 GBG85317.1 - 2.7e-59 200.0 0.1 5.4e-59 199.0 0.1 1.5 1 0 0 1 1 1 1 MT-A70 CLP_protease PF00574.23 GBG85318.1 - 3.5e-16 59.6 0.0 6.1e-08 32.8 0.0 2.3 1 1 1 2 2 2 2 Clp protease CD4-extracel PF09191.10 GBG85319.1 - 1.6 9.2 4.1 5 7.6 0.2 2.4 1 1 1 2 2 2 0 CD4, extracellular RT_RNaseH PF17917.1 GBG85320.1 - 5.3e-22 78.1 0.0 1.4e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85320.1 - 5.8e-22 78.3 0.0 1.4e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85320.1 - 4.5e-21 74.8 0.0 1.7e-20 72.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG85320.1 - 2.6e-08 34.4 0.0 7.5e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG85320.1 - 7.5e-08 32.6 0.0 2.3e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG85320.1 - 2.4e-07 30.6 0.0 4.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG85320.1 - 4.7e-06 27.1 0.0 1.3e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG85320.1 - 0.004 17.0 0.0 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease IL28A PF15177.6 GBG85320.1 - 0.031 14.1 5.5 0.091 12.6 5.5 1.7 1 0 0 1 1 1 0 Interleukin-28A Tudor-knot PF11717.8 GBG85320.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain rve PF00665.26 GBG85321.1 - 7e-32 110.1 0.0 1.8e-14 54.0 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG85321.1 - 1.9e-29 101.6 0.0 4.9e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85321.1 - 9.1e-27 93.4 0.3 2.4e-26 92.1 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85321.1 - 4.2e-23 81.2 1.8 1.7e-14 53.7 0.2 2.9 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG85321.1 - 5.6e-23 81.6 0.3 1.5e-22 80.3 0.3 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribonuc_P_40 PF08584.11 GBG85321.1 - 0.0093 15.3 0.0 0.035 13.4 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit zf-H2C2 PF09337.10 GBG85321.1 - 0.014 15.6 0.0 7.1 7.0 0.0 2.8 2 0 0 2 2 2 0 H2C2 zinc finger rve_3 PF13683.6 GBG85321.1 - 0.034 13.9 0.0 18 5.2 0.0 3.2 2 0 0 2 2 2 0 Integrase core domain Snurportin1 PF11538.8 GBG85321.1 - 0.084 13.1 8.0 0.25 11.5 8.0 1.8 1 0 0 1 1 1 0 Snurportin1 PAS_4 PF08448.10 GBG85321.1 - 0.091 13.0 2.0 12 6.2 0.0 2.8 2 0 0 2 2 2 0 PAS fold RhlB PF12300.8 GBG85321.1 - 0.72 10.0 7.3 1.4 9.0 7.3 1.4 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Histone PF00125.24 GBG85322.1 - 1.8e-17 63.9 0.0 1.8e-17 63.9 0.0 3.2 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 Peptidase_C48 PF02902.19 GBG85322.1 - 1.5e-09 38.0 0.8 3.4e-09 36.9 0.8 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain NUDIX PF00293.28 GBG85323.1 - 4.9e-15 55.7 0.0 8.7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DVL PF08137.12 GBG85323.1 - 0.22 11.4 1.2 0.41 10.6 1.2 1.4 1 0 0 1 1 1 0 DVL family DUF963 PF06131.11 GBG85323.1 - 3.8 7.0 13.4 1.8 8.0 9.6 2.3 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Chorein_N PF12624.7 GBG85324.1 - 6e-12 45.7 0.0 1.9e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 Astro_capsid_p PF12226.8 GBG85324.1 - 0.41 9.7 1.2 0.65 9.1 1.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein KxDL PF10241.9 GBG85325.1 - 0.035 14.4 0.8 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein NACHT_N PF17100.5 GBG85325.1 - 0.18 11.6 1.4 0.31 10.8 1.4 1.4 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase SlyX PF04102.12 GBG85325.1 - 9.4 6.9 6.0 1.3 9.7 0.2 2.5 3 0 0 3 3 3 0 SlyX Peptidase_M41 PF01434.18 GBG85326.1 - 3.3e-65 219.5 0.6 5.2e-65 218.9 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GBG85326.1 - 1.6e-44 151.5 0.0 4.3e-44 150.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG85326.1 - 9.9e-08 31.7 0.6 2.2e-07 30.5 0.1 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 GBG85326.1 - 8.3e-07 29.1 0.0 2.1e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GBG85326.1 - 4.8e-06 26.0 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 GBG85326.1 - 1.2e-05 25.1 0.0 0.0001 22.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GBG85326.1 - 3.5e-05 24.2 0.1 0.0031 17.9 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG85326.1 - 0.00061 20.1 0.0 0.041 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GBG85326.1 - 0.0027 17.6 0.0 0.075 12.9 0.0 2.8 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 GBG85326.1 - 0.0028 17.0 0.2 0.0069 15.8 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GBG85326.1 - 0.0035 17.5 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 GBG85326.1 - 0.0042 16.9 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 GBG85326.1 - 0.0079 16.7 0.0 0.046 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GBG85326.1 - 0.01 15.3 0.1 0.049 13.1 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 GBG85326.1 - 0.018 15.3 0.0 0.078 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG85326.1 - 0.022 14.4 0.5 0.27 10.8 0.2 2.7 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.14 GBG85326.1 - 0.043 13.9 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 GBG85326.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 GBG85326.1 - 0.086 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GBG85326.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 GBG85326.1 - 0.12 12.0 0.2 0.67 9.6 0.0 2.2 2 1 1 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.27 GBG85326.1 - 0.17 12.4 1.1 0.4 11.2 0.4 2.0 2 0 0 2 2 1 0 ABC transporter Zeta_toxin PF06414.12 GBG85326.1 - 0.18 11.1 1.6 0.24 10.7 0.1 2.0 3 0 0 3 3 3 0 Zeta toxin Beta_protein PF14350.6 GBG85326.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Beta protein Parvo_NS1 PF01057.17 GBG85326.1 - 0.22 10.6 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SMP_LBD PF17047.5 GBG85329.1 - 0.014 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 GBG85330.1 - 6.3e-38 129.2 0.1 1e-25 90.0 0.0 2.2 2 0 0 2 2 2 2 C2 domain Acylphosphatase PF00708.18 GBG85332.1 - 1.9 8.9 5.5 23 5.5 3.0 2.5 2 0 0 2 2 2 0 Acylphosphatase Ank_2 PF12796.7 GBG85335.1 - 2.2e-66 220.4 6.1 7.2e-18 65.0 0.0 5.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG85335.1 - 6.6e-59 195.6 18.5 1.6e-12 47.7 1.0 9.3 3 1 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG85335.1 - 4.8e-51 164.8 16.8 3.7e-05 23.8 0.0 11.8 12 0 0 12 12 12 11 Ankyrin repeat Ank PF00023.30 GBG85335.1 - 5e-49 162.7 34.4 8.7e-06 26.0 0.1 11.4 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 GBG85335.1 - 4.6e-47 157.5 29.0 2e-07 31.2 3.2 9.7 2 1 5 9 9 9 9 Ankyrin repeats (many copies) DUF1843 PF08898.10 GBG85335.1 - 2.7 8.6 8.5 33 5.1 0.6 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) VWA_3_C PF18571.1 GBG85335.1 - 3.6 7.5 5.4 82 3.2 0.1 4.5 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain DDE_Tnp_4 PF13359.6 GBG85337.1 - 3.4e-08 33.3 0.0 8.8e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85337.1 - 2.8e-06 27.1 0.0 7.7e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein Spc7 PF08317.11 GBG85337.1 - 0.04 12.8 4.9 0.022 13.7 2.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Phasin PF05597.11 GBG85337.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.5 2 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) APG6_N PF17675.1 GBG85337.1 - 0.2 12.2 15.5 0.034 14.7 6.5 3.0 2 1 2 4 4 4 0 Apg6 coiled-coil region DUF745 PF05335.13 GBG85337.1 - 0.37 10.5 15.3 0.05 13.3 9.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF4695 PF15766.5 GBG85337.1 - 0.55 10.5 3.1 0.66 10.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) Prp19 PF08606.11 GBG85337.1 - 2 8.5 12.7 5.2 7.1 0.2 3.4 2 1 1 3 3 3 0 Prp19/Pso4-like FUSC PF04632.12 GBG85337.1 - 3.9 5.9 9.1 5.1 5.5 9.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.12 GBG85337.1 - 5.9 7.3 13.7 0.57 10.6 5.8 2.8 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Myb_DNA-bind_4 PF13837.6 GBG85338.1 - 4.7e-14 52.5 1.4 4.7e-14 52.5 1.4 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG85338.1 - 1.1e-05 25.5 0.2 2.6e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG85338.1 - 0.013 15.7 0.1 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85338.1 - 0.035 14.4 0.2 0.13 12.5 0.2 2.0 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 GBG85338.1 - 0.064 14.3 0.5 0.14 13.2 0.5 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain HSP70 PF00012.20 GBG85339.1 - 1.1e-96 324.4 0.0 3.9e-80 269.7 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG85339.1 - 1.6e-05 23.9 0.0 0.00064 18.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein gag-asp_proteas PF13975.6 GBG85342.1 - 1.2e-05 25.8 0.2 6.5e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85342.1 - 0.016 15.9 0.0 0.051 14.2 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG85342.1 - 0.089 12.6 1.1 0.16 11.7 1.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Peptidase_C48 PF02902.19 GBG85343.1 - 1.1e-20 74.4 0.0 1.7e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RITA PF17066.5 GBG85343.1 - 0.02 14.5 0.6 0.032 13.8 0.6 1.3 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein RVP_2 PF08284.11 GBG85344.1 - 3e-05 23.8 0.0 0.00012 21.8 0.0 1.9 2 1 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG85344.1 - 0.0019 18.8 0.0 0.0069 17.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Es2 PF09751.9 GBG85344.1 - 0.028 14.2 7.1 0.044 13.5 7.1 1.3 1 0 0 1 1 1 0 Nuclear protein Es2 gag-asp_proteas PF13975.6 GBG85344.1 - 0.17 12.5 0.4 0.91 10.1 0.1 2.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease HSP70 PF00012.20 GBG85345.1 - 2.2e-149 498.5 0.0 2.4e-149 498.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85345.1 - 7.2e-08 31.6 0.1 2.4e-06 26.6 0.1 2.3 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GBG85345.1 - 0.022 15.2 0.0 3.3 8.2 0.0 2.7 2 1 0 2 2 2 0 Cell division protein FtsA PRP4 PF08799.11 GBG85345.1 - 0.034 13.7 0.2 0.35 10.5 0.1 2.3 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like AF0941-like PF14591.6 GBG85345.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 AF0941-like FGGY_C PF02782.16 GBG85345.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 GBG85346.1 - 3.6e-84 283.1 0.0 1.3e-55 188.7 0.0 3.4 3 0 0 3 3 3 2 Hsp70 protein Ldh_1_C PF02866.18 GBG85346.1 - 3.8e-17 62.7 0.0 7.8e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain MULE PF10551.9 GBG85346.1 - 1.1e-13 51.3 0.0 4.1e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain TIM PF00121.18 GBG85346.1 - 4.8e-12 45.8 0.0 5.4e-07 29.2 0.0 3.1 2 1 0 2 2 2 2 Triosephosphate isomerase DBD_Tnp_Mut PF03108.15 GBG85346.1 - 5.3e-10 39.2 0.1 1.4e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 MuDR family transposase MreB_Mbl PF06723.13 GBG85346.1 - 3.7e-07 29.3 0.0 0.041 12.7 0.0 3.8 2 1 0 2 2 2 2 MreB/Mbl protein SWIM PF04434.17 GBG85346.1 - 8.4e-07 28.5 0.0 2.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 SWIM zinc finger Ldh_1_N PF00056.23 GBG85346.1 - 1.3e-06 28.5 0.5 2.9e-06 27.4 0.5 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain zf-CCHC PF00098.23 GBG85346.1 - 0.18 11.9 2.0 0.66 10.2 2.0 2.1 1 0 0 1 1 1 0 Zinc knuckle HSP70 PF00012.20 GBG85348.1 - 3.2e-92 309.6 0.0 1.7e-91 307.2 0.0 2.1 2 1 0 2 2 2 1 Hsp70 protein TIM PF00121.18 GBG85348.1 - 3.3e-09 36.5 0.0 0.0018 17.7 0.0 3.2 3 0 0 3 3 3 2 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG85348.1 - 1.7e-05 23.8 0.4 0.0017 17.2 0.2 3.1 2 1 0 2 2 2 1 MreB/Mbl protein FAM60A PF15396.6 GBG85349.1 - 0.052 13.5 11.6 0.061 13.3 11.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CSRNP_N PF16019.5 GBG85349.1 - 0.16 11.8 6.7 0.18 11.7 6.7 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CDC27 PF09507.10 GBG85349.1 - 0.7 9.2 25.5 0.75 9.1 25.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF5401 PF17380.2 GBG85349.1 - 1 7.4 28.2 1.1 7.3 28.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Rtf2 PF04641.12 GBG85349.1 - 1.9 7.8 20.2 2.3 7.5 20.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.12 GBG85349.1 - 2.4 7.9 20.3 3.1 7.5 20.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMPIT PF07851.13 GBG85349.1 - 7.1 5.8 11.6 8.4 5.5 11.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein VIR_N PF15912.5 GBG85349.1 - 9.8 5.7 13.9 12 5.4 13.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Myb_DNA-bind_4 PF13837.6 GBG85350.1 - 9e-08 32.4 1.3 1.8e-07 31.4 1.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG85350.1 - 0.00016 21.8 2.3 0.0025 17.9 2.3 2.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85350.1 - 0.0091 16.3 1.2 0.021 15.2 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG85350.1 - 0.11 12.7 1.8 0.46 10.8 1.6 2.1 1 1 1 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG85350.1 - 0.11 12.5 3.6 0.21 11.7 3.6 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain HSP70 PF00012.20 GBG85351.1 - 2e-87 293.8 0.0 3.6e-60 203.8 0.1 2.2 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG85351.1 - 1.5e-10 40.4 0.2 4.3e-08 32.3 0.1 2.9 2 1 0 2 2 2 2 MreB/Mbl protein TIM PF00121.18 GBG85351.1 - 1.3e-09 37.9 0.0 6.1e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Triosephosphate isomerase DUF2408 PF10303.9 GBG85351.1 - 0.086 13.4 0.2 0.22 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) UnbV_ASPIC PF07593.12 GBG85351.1 - 0.1 12.6 0.6 0.53 10.3 0.1 2.3 2 0 0 2 2 2 0 ASPIC and UnbV DDE_Tnp_4 PF13359.6 GBG85352.1 - 6.5e-26 90.9 0.0 9.6e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85352.1 - 3.1e-09 36.7 0.0 5.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85352.1 - 4.6e-07 29.7 0.1 3.1e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain LVIVD PF08309.11 GBG85353.1 - 1.4e-06 27.5 0.1 0.76 9.1 0.0 4.6 4 0 0 4 4 4 3 LVIVD repeat FrhB_FdhB_N PF04422.13 GBG85353.1 - 1.8e-05 24.8 2.3 6.9 6.9 0.0 4.5 4 0 0 4 4 4 2 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term NHL PF01436.21 GBG85353.1 - 0.0001 22.2 0.0 0.83 9.8 0.0 4.1 3 0 0 3 3 3 1 NHL repeat Crystall_4 PF17945.1 GBG85353.1 - 0.0004 20.8 6.1 4.2 7.9 0.0 4.4 4 0 0 4 4 4 2 Beta/Gamma crystallin DUF3562 PF12085.8 GBG85353.1 - 0.00046 19.7 0.2 23 4.7 0.0 4.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3562) Med13_C PF06333.12 GBG85353.1 - 0.029 13.6 2.1 7.5 5.7 0.0 4.0 3 0 0 3 3 3 0 Mediator complex subunit 13 C-terminal domain HSP70 PF00012.20 GBG85354.1 - 9.8e-89 298.1 0.0 1.5e-88 297.6 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein TIM PF00121.18 GBG85354.1 - 1.8e-10 40.6 0.0 6.7e-08 32.2 0.0 3.1 2 1 0 2 2 2 2 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG85354.1 - 0.0022 16.8 0.6 0.085 11.7 0.2 2.9 2 1 0 2 2 2 1 MreB/Mbl protein Usp PF00582.26 GBG85355.1 - 0.06 13.8 0.1 0.11 13.0 0.0 1.6 2 0 0 2 2 2 0 Universal stress protein family HSP70 PF00012.20 GBG85356.1 - 4.5e-129 431.4 0.0 5.8e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85356.1 - 2.8e-11 42.8 0.5 4.8e-11 42.1 0.5 1.3 1 0 0 1 1 1 1 MreB/Mbl protein MutL PF13941.6 GBG85356.1 - 0.049 12.2 0.0 0.078 11.6 0.0 1.3 1 0 0 1 1 1 0 MutL protein FGGY_C PF02782.16 GBG85356.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BUD22 PF09073.10 GBG85357.1 - 1.1 8.5 27.1 1.6 8.0 27.1 1.2 1 0 0 1 1 1 0 BUD22 TMEM174 PF15029.6 GBG85357.1 - 1.9 8.1 0.0 1.9 8.1 0.0 2.3 1 1 1 2 2 2 0 Transmembrane protein 174 Lin-8 PF03353.15 GBG85357.1 - 2.1 7.8 14.6 2.8 7.4 14.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HSP70 PF00012.20 GBG85358.1 - 5.3e-78 262.7 0.0 6e-53 180.0 0.0 2.3 2 0 0 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG85358.1 - 1.2e-32 113.3 0.0 1.8e-13 50.5 0.0 4.9 5 0 0 5 5 5 4 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG85358.1 - 8.5e-05 21.5 1.0 0.0064 15.4 0.1 3.9 4 1 0 4 4 4 1 MreB/Mbl protein DDR PF08841.10 GBG85358.1 - 0.0067 15.5 0.5 0.019 14.0 0.1 1.9 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain LPD11 PF18824.1 GBG85358.1 - 0.14 12.3 0.1 1.4 9.1 0.0 2.6 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 HSP70 PF00012.20 GBG85359.1 - 2.4e-148 495.0 0.0 2.9e-148 494.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85359.1 - 2.5e-16 59.4 0.0 5.9e-15 54.9 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 GBG85359.1 - 0.012 14.8 0.1 1 8.6 0.0 2.5 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.6 GBG85359.1 - 0.014 15.8 0.0 2 8.9 0.0 3.1 2 1 0 2 2 2 0 Cell division protein FtsA StbA PF06406.11 GBG85359.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.16 GBG85359.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Methyltransf_14 PF08484.11 GBG85359.1 - 0.16 11.8 0.0 0.51 10.1 0.0 1.8 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain Ub-RnfH PF03658.14 GBG85360.1 - 0.096 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 RnfH family Ubiquitin JmjC PF02373.22 GBG85361.1 - 0.066 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase HSP70 PF00012.20 GBG85363.1 - 1.4e-143 479.2 0.0 1.4e-143 479.2 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85363.1 - 3.8e-10 39.1 0.2 3.3e-09 36.0 0.1 2.3 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GBG85363.1 - 0.0088 16.4 0.1 0.98 9.9 0.1 2.7 2 1 0 2 2 2 1 Cell division protein FtsA DDE_Tnp_4 PF13359.6 GBG85364.1 - 4.9e-17 62.0 0.0 7.2e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85364.1 - 1.6e-14 54.0 0.0 3.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG85365.1 - 3e-06 27.5 0.1 6.2e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG85365.1 - 1.7e-05 24.8 0.9 3.7e-05 23.7 0.9 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG85365.1 - 0.038 14.2 1.2 0.19 12.0 1.2 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain Nop14 PF04147.12 GBG85365.1 - 0.42 8.8 51.4 0.0059 14.9 42.0 2.0 2 0 0 2 2 2 0 Nop14-like family Presenilin PF01080.17 GBG85365.1 - 1 8.1 2.2 1.6 7.5 2.2 1.4 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG85365.1 - 5.5 5.7 15.3 8.9 5.0 15.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HSP70 PF00012.20 GBG85367.1 - 3.4e-84 283.2 0.0 1.1e-64 218.8 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG85367.1 - 1.3e-12 47.6 0.0 1.2e-09 37.9 0.0 2.7 2 1 0 2 2 2 2 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG85367.1 - 1.9e-06 26.9 1.6 5.5e-06 25.4 0.0 2.4 2 1 0 2 2 2 1 MreB/Mbl protein DUF1275 PF06912.11 GBG85369.1 - 0.016 15.2 1.1 0.016 15.2 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) RT_RNaseH PF17917.1 GBG85370.1 - 3.1e-25 88.5 0.0 7.2e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85370.1 - 7.1e-22 77.3 0.0 2.1e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85370.1 - 1.2e-19 70.2 0.2 2.6e-19 69.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85370.1 - 9.8e-09 35.4 0.0 5e-08 33.2 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85370.1 - 0.017 15.3 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DUF4187 PF13821.6 GBG85370.1 - 0.05 13.4 2.1 0.21 11.4 2.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG85370.1 - 0.11 12.8 0.2 0.11 12.8 0.2 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein IBR PF01485.21 GBG85370.1 - 0.14 12.4 2.6 9.3 6.6 0.5 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FAM76 PF16046.5 GBG85370.1 - 0.55 9.5 7.2 1.6 8.0 7.2 1.7 1 0 0 1 1 1 0 FAM76 protein eIF3_subunit PF08597.10 GBG85370.1 - 9.4 6.1 13.9 17 5.3 13.9 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Arf PF00025.21 GBG85371.1 - 3.5e-36 124.3 0.0 6.3e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GBG85371.1 - 8.7e-06 25.8 0.0 3.3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 GBG85371.1 - 1.8e-05 24.3 0.1 0.00019 20.9 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GBG85371.1 - 4.8e-05 23.6 0.0 0.00013 22.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GBG85371.1 - 0.00013 21.6 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GBG85371.1 - 0.0002 20.7 1.5 0.024 13.8 0.0 2.7 2 1 1 3 3 3 2 G-protein alpha subunit DUF16 PF01519.16 GBG85371.1 - 4.3 7.9 12.5 0.95 10.0 3.7 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Myb_DNA-bind_4 PF13837.6 GBG85372.1 - 2.8e-08 34.0 0.9 5e-08 33.2 0.9 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85372.1 - 0.035 14.4 0.3 0.062 13.6 0.3 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RT_RNaseH PF17917.1 GBG85375.1 - 1.3e-20 73.7 0.0 2.4e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85375.1 - 1.3e-19 70.1 0.0 2.4e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85375.1 - 6.8e-07 29.3 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85375.1 - 7.2e-07 28.9 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG85375.1 - 6.1e-05 23.5 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85375.1 - 0.0062 17.1 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85375.1 - 0.0082 15.9 1.2 0.015 15.0 1.2 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85375.1 - 0.013 15.8 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Iso_dh PF00180.20 GBG85376.1 - 1.7e-79 267.5 0.0 2e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Mad3_BUB1_I PF08311.12 GBG85377.1 - 1.3e-38 131.8 0.2 2.3e-38 130.9 0.2 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 GBG85377.1 - 0.016 15.4 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein TFIIA PF03153.13 GBG85377.1 - 5.2 6.9 7.8 5.9 6.8 1.5 3.1 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF616 PF04765.13 GBG85378.1 - 9e-123 409.5 0.0 1.3e-122 409.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF616) EPL1 PF10513.9 GBG85378.1 - 0.1 13.0 2.4 0.11 12.8 0.2 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like SBF PF01758.16 GBG85380.1 - 0.00047 19.9 0.1 0.00047 19.9 0.1 1.5 2 0 0 2 2 2 1 Sodium Bile acid symporter family Serinc PF03348.15 GBG85381.1 - 0.29 10.0 0.2 0.43 9.4 0.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4746 PF15928.5 GBG85381.1 - 0.56 9.6 15.4 0.7 9.3 15.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4407 PF14362.6 GBG85381.1 - 8.3 5.7 8.6 11 5.3 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CCHC PF00098.23 GBG85382.1 - 7.7e-06 25.8 1.4 1.4e-05 24.9 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG85382.1 - 0.0037 17.1 2.5 0.0061 16.3 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle LMBR1 PF04791.16 GBG85382.1 - 0.43 9.4 1.8 0.49 9.2 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4829 PF16111.5 GBG85383.1 - 0.046 14.5 0.6 0.046 14.5 0.6 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4829) RT_RNaseH_2 PF17919.1 GBG85384.1 - 2.2e-68 226.6 0.1 3.4e-33 113.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85384.1 - 1.2e-46 157.3 0.0 5.2e-23 81.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85384.1 - 6.1e-44 150.2 2.2 6.3e-32 110.9 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG85384.1 - 2.4e-18 66.0 0.3 9.2e-18 64.1 0.3 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85384.1 - 1.1e-12 48.1 0.0 3.8e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85384.1 - 0.05 13.8 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG85385.1 - 2.8e-33 113.9 0.0 5.4e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85385.1 - 5.3e-33 114.4 0.1 7.9e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85385.1 - 5.2e-24 84.5 0.0 1e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rab3-GTPase_cat PF13890.6 GBG85385.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit DDE_Tnp_4 PF13359.6 GBG85386.1 - 1.3e-09 37.9 0.1 2.5e-09 37.0 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease RT_RNaseH PF17917.1 GBG85387.1 - 3.9e-19 68.9 0.0 7.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85387.1 - 1.2e-18 66.9 0.0 2.1e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85387.1 - 5.9e-16 58.3 0.7 1.2e-15 57.3 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85387.1 - 9.6e-11 41.6 0.6 5.5e-10 39.1 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG85387.1 - 0.021 13.9 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 Integrin_b_cyt PF08725.11 GBG85387.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain COR PF16095.5 GBG85388.1 - 6.7e-10 39.1 0.0 2.6e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 GBG85388.1 - 1.2e-05 25.5 0.0 3.6e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Snapin_Pallidin PF14712.6 GBG85388.1 - 0.055 13.9 0.1 0.23 11.9 0.1 2.1 1 0 0 1 1 1 0 Snapin/Pallidin Chloroa_b-bind PF00504.21 GBG85389.1 - 0.00018 22.0 0.2 0.0041 17.6 0.1 2.0 1 1 1 2 2 2 2 Chlorophyll A-B binding protein RVT_1 PF00078.27 GBG85391.1 - 9.3e-15 54.7 1.2 1.2e-07 31.4 0.0 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 GBG85391.1 - 1.2e-10 41.0 0.6 6.5e-10 38.7 0.6 2.3 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region DBD_Tnp_Hermes PF10683.9 GBG85391.1 - 1.5e-05 24.6 0.0 4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain FRG1 PF06229.12 GBG85391.1 - 4.3 7.0 12.9 0.098 12.4 5.1 2.3 2 0 0 2 2 2 0 FRG1-like domain RVT_1 PF00078.27 GBG85392.1 - 1.9e-33 115.9 0.0 4.7e-33 114.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85392.1 - 1.8e-32 111.3 0.0 1.1e-31 108.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85392.1 - 7.4e-30 103.3 0.0 2.7e-29 101.5 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85392.1 - 1.6e-12 47.4 0.3 4.4e-12 45.9 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG85392.1 - 4.2e-08 33.1 0.0 7.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease TPR_MLP1_2 PF07926.12 GBG85392.1 - 9.5e-07 28.9 18.3 9.5e-07 28.9 18.3 4.2 3 2 1 4 4 3 1 TPR/MLP1/MLP2-like protein Asp_protease_2 PF13650.6 GBG85392.1 - 3.9e-05 24.2 0.0 8.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85392.1 - 0.00017 22.1 0.0 0.00052 20.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Cluap1 PF10234.9 GBG85392.1 - 0.00022 20.8 11.6 0.00022 20.8 11.6 2.0 2 0 0 2 2 2 1 Clusterin-associated protein-1 ATG16 PF08614.11 GBG85392.1 - 0.0018 18.5 17.8 0.0018 18.5 17.8 3.9 2 2 1 3 3 2 1 Autophagy protein 16 (ATG16) DUF1758 PF05585.12 GBG85392.1 - 0.0022 17.8 0.1 0.0089 15.8 0.0 2.0 2 0 0 2 2 2 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG85392.1 - 0.0042 17.3 0.0 0.023 14.9 0.1 2.4 2 0 0 2 2 1 1 H2C2 zinc finger DUF5338 PF17273.2 GBG85392.1 - 0.0067 16.5 0.0 0.03 14.4 0.0 2.1 1 0 0 1 1 1 1 Family of unknown function (DUF5338) SlyX PF04102.12 GBG85392.1 - 0.014 16.0 20.5 0.047 14.3 0.7 5.7 4 2 1 5 5 5 0 SlyX BLOC1_2 PF10046.9 GBG85392.1 - 0.018 15.4 0.5 0.018 15.4 0.5 3.8 3 1 1 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC92 PF14916.6 GBG85392.1 - 0.023 14.5 6.4 0.076 12.8 3.8 3.0 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Retrotrans_gag PF03732.17 GBG85392.1 - 0.023 15.0 1.6 4.3 7.7 0.0 3.5 3 0 0 3 3 2 0 Retrotransposon gag protein HALZ PF02183.18 GBG85392.1 - 0.075 13.3 6.4 0.24 11.7 0.5 3.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1664 PF07889.12 GBG85392.1 - 0.99 9.4 13.2 2.3 8.3 1.2 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 GBG85392.1 - 1.5 9.1 20.8 76 3.6 20.0 3.3 1 1 0 1 1 1 0 Tho complex subunit 7 FapA PF03961.13 GBG85392.1 - 1.5 7.3 11.8 3.4 6.2 11.1 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A MPS2 PF17060.5 GBG85392.1 - 2.5 7.3 12.0 3.4 6.8 9.9 2.1 2 0 0 2 2 2 0 Monopolar spindle protein 2 Bacillus_HBL PF05791.11 GBG85392.1 - 2.8 7.7 12.7 0.63 9.9 3.1 2.8 3 0 0 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) DASH_Dad3 PF08656.10 GBG85392.1 - 4.2 7.5 6.6 4.9 7.3 0.2 3.8 5 0 0 5 5 3 0 DASH complex subunit Dad3 NPV_P10 PF05531.12 GBG85392.1 - 7 7.2 7.0 7.1 7.2 0.9 3.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.18 GBG85392.1 - 7.1 7.4 7.5 77 4.1 1.6 3.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus RVT_1 PF00078.27 GBG85393.1 - 3.3e-24 85.6 0.1 4.8e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HrpB7 PF09486.10 GBG85394.1 - 2.7 8.4 13.1 2.5 8.5 10.1 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.9 GBG85394.1 - 3.4 6.7 9.0 0.94 8.5 6.0 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Allexi_40kDa PF05549.11 GBG85394.1 - 6.5 6.2 8.4 6.1 6.3 0.7 2.4 2 1 1 3 3 3 0 Allexivirus 40kDa protein RVT_1 PF00078.27 GBG85395.1 - 2.3e-18 66.5 0.1 3.5e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG85395.1 - 2.3e-08 33.9 0.0 5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG85395.1 - 4.5e-08 33.6 0.0 1.9e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85395.1 - 2e-05 25.0 0.0 5.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG85395.1 - 0.0058 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG85395.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RT_RNaseH_2 PF17919.1 GBG85396.1 - 1.2e-31 108.7 0.0 2.6e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85396.1 - 1.8e-26 92.5 0.0 3.1e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85396.1 - 2.6e-24 86.0 0.2 9.5e-24 84.1 0.2 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG85396.1 - 0.51 10.5 2.5 1 9.6 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG85397.1 - 1.3e-08 35.0 0.4 2e-08 34.5 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG85397.1 - 0.021 14.9 0.6 0.037 14.1 0.6 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG85397.1 - 0.032 14.4 0.6 0.091 13.0 0.6 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain Retrotrans_gag PF03732.17 GBG85398.1 - 4.8e-06 26.8 4.9 0.0082 16.4 0.1 3.6 3 0 0 3 3 3 2 Retrotransposon gag protein FlxA PF14282.6 GBG85398.1 - 0.00039 20.4 1.9 0.0071 16.3 0.1 3.1 3 0 0 3 3 3 1 FlxA-like protein SlyX PF04102.12 GBG85398.1 - 0.0065 17.1 7.8 0.17 12.6 2.8 3.0 1 1 1 2 2 2 2 SlyX APG6_N PF17675.1 GBG85398.1 - 0.021 15.3 0.3 0.05 14.1 0.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region RVP_2 PF08284.11 GBG85398.1 - 0.056 13.2 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease CEP63 PF17045.5 GBG85398.1 - 0.069 13.1 0.4 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa CLZ PF16526.5 GBG85398.1 - 2.9 8.3 6.5 8.3 6.9 0.3 3.5 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 GBG85398.1 - 3.6 7.9 4.7 8.2 6.8 0.6 2.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain DDE_Tnp_4 PF13359.6 GBG85399.1 - 6.5e-26 90.9 0.0 1.6e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85399.1 - 9.1e-12 45.0 0.0 3.1e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85399.1 - 0.018 14.7 1.3 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Transposase DDE domain NinG PF05766.12 GBG85399.1 - 0.38 10.7 4.5 1.3 9.0 4.5 1.9 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Casc1_N PF15927.5 GBG85399.1 - 0.46 10.2 15.5 0.16 11.7 7.7 2.5 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Myb_DNA-bind_4 PF13837.6 GBG85400.1 - 3.2e-08 33.8 1.5 3.2e-08 33.8 1.5 2.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85400.1 - 0.0017 18.7 1.6 0.0025 18.1 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG85400.1 - 0.017 15.4 0.8 0.036 14.3 0.8 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain BUD22 PF09073.10 GBG85401.1 - 0.77 9.0 48.9 1.2 8.4 48.9 1.4 1 0 0 1 1 1 0 BUD22 DDE_Tnp_4 PF13359.6 GBG85402.1 - 2.3e-11 43.6 0.0 6.6e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85402.1 - 4.6e-06 26.4 0.0 7.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85402.1 - 0.0086 15.7 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain BRD4_CDT PF17105.5 GBG85402.1 - 1.1 9.0 5.0 2.1 8.0 5.0 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 PHO4 PF01384.20 GBG85403.1 - 2.8e-105 352.1 17.9 3.4e-105 351.8 17.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family Pkinase PF00069.25 GBG85405.1 - 0.0015 18.0 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase PF00069.25 GBG85406.1 - 0.0092 15.4 0.0 0.7 9.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain GAS PF13851.6 GBG85408.1 - 0.0094 15.3 2.6 0.0094 15.3 2.6 2.1 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding FOXP-CC PF16159.5 GBG85408.1 - 1.7 9.3 5.0 0.64 10.7 0.2 2.5 3 1 0 3 3 3 0 FOXP coiled-coil domain PHO4 PF01384.20 GBG85409.1 - 2.7e-99 332.4 25.2 3.3e-99 332.1 25.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family LMBR1 PF04791.16 GBG85409.1 - 0.064 12.2 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein RVT_1 PF00078.27 GBG85411.1 - 2e-30 106.0 0.1 3e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG85411.1 - 6.8e-07 29.8 0.0 2.4e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85411.1 - 8.3e-07 29.5 0.0 4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG85411.1 - 5.3e-06 26.2 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG85411.1 - 1.2e-05 25.5 0.0 3.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG85411.1 - 7.7e-05 22.5 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG85412.1 - 0.00029 21.0 10.5 0.0035 17.6 0.1 4.6 4 1 0 4 4 4 1 Retrotransposon gag protein SPARC_Ca_bdg PF10591.9 GBG85412.1 - 0.023 15.0 2.7 0.023 15.0 2.7 2.0 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region NPV_P10 PF05531.12 GBG85412.1 - 0.076 13.5 1.2 0.8 10.2 0.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Scaffolding_pro PF11418.8 GBG85412.1 - 0.91 10.1 4.2 17 6.0 0.1 3.1 3 0 0 3 3 3 0 Phi29 scaffolding protein HIP1_clath_bdg PF16515.5 GBG85412.1 - 3.5 8.3 19.9 0.048 14.3 3.5 3.5 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Siah-Interact_N PF09032.11 GBG85412.1 - 8.2 6.8 8.7 30 5.0 5.9 3.0 2 1 0 2 2 2 0 Siah interacting protein, N terminal Myb_DNA-bind_4 PF13837.6 GBG85413.1 - 5.6e-09 36.3 0.9 9.6e-09 35.5 0.9 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG85413.1 - 8.7e-05 22.6 0.3 0.00016 21.8 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG85413.1 - 0.012 15.8 0.2 0.024 14.9 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG85413.1 - 0.026 14.6 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85413.1 - 0.11 12.8 1.3 0.25 11.7 0.3 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVT_1 PF00078.27 GBG85414.1 - 2.4e-19 69.8 0.0 3.5e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG85414.1 - 1e-07 32.5 0.0 1.9e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85414.1 - 8.4e-07 29.5 0.0 1.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG85414.1 - 6.9e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85414.1 - 0.00036 20.3 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG85414.1 - 0.012 15.6 0.0 0.053 13.6 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG85414.1 - 0.15 11.1 0.0 0.29 10.2 0.0 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 Med4 PF10018.9 GBG85415.1 - 0.0026 17.5 1.9 0.0026 17.5 1.9 2.0 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 HIP1_clath_bdg PF16515.5 GBG85415.1 - 0.0044 17.6 7.3 0.0044 17.6 7.3 2.6 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 SPARC_Ca_bdg PF10591.9 GBG85415.1 - 0.076 13.3 1.5 0.18 12.1 1.3 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region COMP PF11598.8 GBG85415.1 - 1.3 9.5 5.9 8.5 6.9 1.4 2.5 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Myb_DNA-bind_4 PF13837.6 GBG85416.1 - 2.5e-09 37.4 1.3 3.5e-09 36.9 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85416.1 - 0.015 15.6 0.0 0.041 14.2 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PHO4 PF01384.20 GBG85417.1 - 8.4e-90 301.2 20.9 8.4e-90 301.2 20.9 1.9 1 1 1 2 2 2 1 Phosphate transporter family Shisa PF13908.6 GBG85417.1 - 1.1 9.5 3.8 2.2 8.5 3.8 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 GBG85417.1 - 4.6 8.3 5.1 12 6.9 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SDA1 PF05285.12 GBG85418.1 - 0.11 11.9 9.4 0.13 11.7 9.4 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 GBG85418.1 - 0.43 10.2 6.5 0.56 9.9 6.5 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Plasmodium_Vir PF05795.11 GBG85418.1 - 0.91 8.9 2.9 1.2 8.5 2.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SAPS PF04499.15 GBG85418.1 - 1.2 7.9 2.9 1.3 7.7 2.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GBG85418.1 - 3.5 6.3 6.0 4.3 6.0 6.0 1.1 1 0 0 1 1 1 0 Presenilin RT_RNaseH PF17917.1 GBG85419.1 - 4.2e-21 75.2 0.0 8.4e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85419.1 - 3.7e-20 71.8 0.0 8.3e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85419.1 - 3e-15 56.5 0.0 7.3e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG85419.1 - 8.3e-15 54.7 0.1 1.9e-14 53.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG85419.1 - 3.5e-08 33.9 0.0 7.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG85419.1 - 3.9e-08 33.1 0.0 7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG85419.1 - 3.4e-05 24.4 0.0 7.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG85419.1 - 4.8e-05 23.5 0.0 0.00014 22.0 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG85419.1 - 0.00047 19.9 0.2 0.00088 19.1 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85419.1 - 0.031 14.6 0.0 0.088 13.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG85420.1 - 0.0077 16.5 0.3 0.023 15.0 0.0 2.0 2 1 0 2 2 2 1 Retrotransposon gag protein NOP19 PF10863.8 GBG85420.1 - 0.11 12.3 0.1 0.3 10.9 0.1 1.7 1 1 0 1 1 1 0 Nucleolar protein 19 BTB PF00651.31 GBG85421.1 - 1.5e-14 54.2 0.0 7e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 GBG85422.1 - 3.1e-07 30.6 0.0 6.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Glyco_transf_34 PF05637.12 GBG85423.1 - 5.6e-15 55.7 0.1 3.7e-14 53.0 0.1 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family SR-25 PF10500.9 GBG85423.1 - 0.0057 16.3 16.0 0.0091 15.6 16.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein EIIBC-GUT_N PF03612.14 GBG85423.1 - 0.017 14.9 2.0 0.023 14.4 2.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_S49_N PF08496.10 GBG85423.1 - 0.066 13.3 7.5 0.1 12.6 7.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med19 PF10278.9 GBG85423.1 - 0.14 12.1 12.2 0.22 11.5 12.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AP3D1 PF06375.11 GBG85423.1 - 0.15 12.3 12.7 0.25 11.6 12.7 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Eapp_C PF10238.9 GBG85423.1 - 0.19 11.8 3.9 0.3 11.2 3.9 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein U79_P34 PF03064.16 GBG85423.1 - 0.26 10.6 10.1 0.42 9.9 10.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HA2 PF04408.23 GBG85423.1 - 0.27 11.5 1.3 0.54 10.6 1.3 1.4 1 0 0 1 1 1 0 Helicase associated domain (HA2) Coilin_N PF15862.5 GBG85423.1 - 0.82 9.5 13.1 1.5 8.6 13.1 1.4 1 0 0 1 1 1 0 Coilin N-terminus Pox_P4B PF03292.14 GBG85423.1 - 3.1 6.0 4.6 4.2 5.5 4.6 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein OAD_gamma PF04277.13 GBG85423.1 - 3.8 8.2 6.2 6.7 7.4 6.2 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain NARP1 PF12569.8 GBG85423.1 - 4.9 5.9 10.1 6.9 5.4 10.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pkinase PF00069.25 GBG85425.1 - 1.3e-12 47.7 0.0 3.4e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG85425.1 - 6.6e-09 35.4 0.0 2.5e-08 33.5 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GBG85425.1 - 0.0002 21.4 1.7 0.00045 20.2 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Syncollin PF15138.6 GBG85425.1 - 0.0092 16.2 0.0 0.028 14.6 0.0 1.8 1 0 0 1 1 1 1 Syncollin PHM7_cyt PF14703.6 GBG85425.1 - 0.042 14.1 0.1 7.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Pkinase_fungal PF17667.1 GBG85425.1 - 0.08 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 GBG85426.1 - 1.2e-38 132.9 0.0 2.7e-38 131.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG85426.1 - 1.2e-38 133.0 0.0 2e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG85426.1 - 0.00016 21.7 0.0 0.00043 20.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family PD40 PF07676.12 GBG85426.1 - 0.0057 16.6 0.0 0.026 14.5 0.0 2.2 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat Pkinase_fungal PF17667.1 GBG85426.1 - 0.029 13.1 0.0 0.029 13.1 0.0 2.3 2 1 0 2 2 2 0 Fungal protein kinase SR-25 PF10500.9 GBG85426.1 - 0.47 10.0 21.7 0.023 14.3 12.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Yae1_N PF09811.9 GBG85429.1 - 0.088 12.5 5.6 34 4.2 0.0 6.1 6 0 0 6 6 6 0 Essential protein Yae1, N terminal SusD-like PF12741.7 GBG85429.1 - 0.31 9.9 1.4 20 3.9 0.0 3.3 3 1 0 3 3 3 0 Susd and RagB outer membrane lipoprotein PIF1 PF05970.14 GBG85431.1 - 1.7e-45 155.8 0.0 2.7e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Pkinase_Tyr PF07714.17 GBG85433.1 - 3.2e-39 134.8 0.0 5.9e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG85433.1 - 9.8e-39 133.3 0.0 1.9e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG85433.1 - 7.1e-05 22.8 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG85433.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Syncollin PF15138.6 GBG85433.1 - 0.018 15.2 0.0 0.061 13.5 0.0 1.9 2 0 0 2 2 2 0 Syncollin THDPS_N_2 PF14805.6 GBG85433.1 - 0.077 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Asp_protease_2 PF13650.6 GBG85434.1 - 0.001 19.6 0.1 0.05 14.2 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85434.1 - 0.005 17.4 0.3 0.038 14.6 0.0 2.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Nop14 PF04147.12 GBG85435.1 - 0.26 9.4 46.8 0.074 11.3 17.0 2.1 2 0 0 2 2 2 0 Nop14-like family DUF2052 PF09747.9 GBG85435.1 - 0.32 11.1 36.9 0.062 13.4 14.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SID-1_RNA_chan PF13965.6 GBG85435.1 - 0.36 9.2 2.6 4.5 5.5 0.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CPSF100_C PF13299.6 GBG85435.1 - 0.36 11.0 19.3 0.035 14.3 5.6 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Adaptin_binding PF10199.9 GBG85435.1 - 0.44 11.2 18.7 0.19 12.4 2.8 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF3408 PF11888.8 GBG85435.1 - 0.62 10.2 18.3 0.71 10.0 9.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DDHD PF02862.17 GBG85435.1 - 1.1 9.4 8.1 2.2 8.4 1.5 2.2 2 0 0 2 2 2 0 DDHD domain Sigma70_ner PF04546.13 GBG85435.1 - 1.1 9.1 38.9 0.084 12.8 13.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region SpoIIIAH PF12685.7 GBG85435.1 - 1.1 9.0 19.8 0.15 11.9 2.8 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF5523 PF17661.1 GBG85435.1 - 1.4 8.6 35.7 0.14 11.8 15.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) BUD22 PF09073.10 GBG85435.1 - 1.4 8.2 41.2 0.029 13.7 12.8 2.1 2 0 0 2 2 2 0 BUD22 RR_TM4-6 PF06459.12 GBG85435.1 - 1.5 8.5 24.0 0.13 12.0 9.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 GBG85435.1 - 1.9 6.9 46.1 0.086 11.3 17.8 2.1 2 0 0 2 2 2 0 Mpp10 protein SDA1 PF05285.12 GBG85435.1 - 2.4 7.5 49.4 0.019 14.4 15.4 2.1 2 0 0 2 2 2 0 SDA1 DUF719 PF05334.13 GBG85435.1 - 3.2 7.9 14.6 0.036 14.3 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) FAM60A PF15396.6 GBG85435.1 - 3.5 7.6 11.1 6.7 6.7 1.2 3.0 3 0 0 3 3 3 0 Protein Family FAM60A AFT PF08731.11 GBG85435.1 - 3.8 7.9 5.4 1.6 9.1 0.2 2.3 2 0 0 2 2 2 0 Transcription factor AFT RNA_pol_Rpc4 PF05132.14 GBG85435.1 - 3.9 7.9 16.6 6 7.3 6.5 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4471 PF14740.6 GBG85435.1 - 5.2 6.2 10.1 3.6 6.7 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Rxt3 PF08642.10 GBG85435.1 - 5.3 7.8 6.0 1.7 9.4 0.2 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 SpoIIP PF07454.11 GBG85435.1 - 6.8 6.1 20.5 1.7 8.0 7.4 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.10 GBG85435.1 - 7 6.9 24.9 1.3 9.4 7.4 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 MRNIP PF15749.5 GBG85435.1 - 9.9 6.9 19.3 2.5 8.8 5.4 2.4 2 0 0 2 2 2 0 MRN-interacting protein DDE_Tnp_4 PF13359.6 GBG85436.1 - 4.6e-31 107.6 0.0 4.8e-30 104.3 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85436.1 - 5.3e-14 52.3 0.0 8.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG85436.1 - 6.5e-05 23.2 0.2 0.00046 20.5 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG85436.1 - 0.00032 20.4 1.0 0.045 13.4 0.3 3.2 3 1 0 3 3 3 1 Transposase DDE domain Tetraspanin PF00335.20 GBG85438.1 - 3e-11 43.5 3.1 4.1e-11 43.0 3.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Fer4_4 PF12800.7 GBG85438.1 - 0.53 10.9 8.9 0.57 10.8 2.1 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain NAP PF00956.18 GBG85439.1 - 4.4e-67 226.1 0.0 2.4e-66 223.7 0.0 2.0 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 PF11705.8 GBG85439.1 - 0.066 13.5 11.1 0.13 12.5 11.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SAP PF02037.27 GBG85441.1 - 2.3e-05 24.0 0.0 2.3e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 SAP domain RT_RNaseH_2 PF17919.1 GBG85443.1 - 3.2e-23 81.6 0.0 6.7e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85443.1 - 2.6e-21 75.9 0.1 9.2e-21 74.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85443.1 - 6.2e-15 55.3 0.1 1.5e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG85443.1 - 0.0081 16.4 0.3 0.037 14.3 0.3 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG85444.1 - 2e-22 79.8 0.0 3.5e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF998 PF06197.13 GBG85445.1 - 0.0058 16.3 0.1 0.0086 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF998) TRAM_LAG1_CLN8 PF03798.16 GBG85446.1 - 2.7e-12 46.8 10.0 3.1e-12 46.7 10.0 1.0 1 0 0 1 1 1 1 TLC domain DUF2236 PF09995.9 GBG85446.1 - 0.12 12.5 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) DUF659 PF04937.15 GBG85447.1 - 9.9e-30 103.4 0.0 6.1e-29 100.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG85448.1 - 9.7e-08 31.8 0.1 1.7e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG85448.1 - 7.3e-07 29.0 0.0 2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG85448.1 - 1.6e-06 28.6 0.0 4.7e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85448.1 - 2.1e-06 28.3 0.0 4.8e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG85448.1 - 0.0054 17.0 0.1 0.0054 17.0 0.1 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG85448.1 - 0.013 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG85449.1 - 2e-26 92.5 0.0 5.2e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85449.1 - 4.8e-07 29.6 0.0 7.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein CPSF73-100_C PF11718.8 GBG85452.1 - 0.23 11.0 3.7 4.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term AOX PF01786.17 GBG85453.1 - 2.6e-78 262.5 0.1 3.4e-78 262.1 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-CCHC PF00098.23 GBG85454.1 - 2.5e-08 33.6 3.8 5.1e-08 32.6 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG85454.1 - 0.014 15.1 3.5 0.014 15.1 3.5 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG85454.1 - 0.018 14.8 2.1 0.018 14.8 2.1 1.8 2 0 0 2 2 2 0 Zinc knuckle UPF0524 PF15823.5 GBG85454.1 - 0.31 10.4 8.5 0.63 9.4 8.5 1.6 1 1 0 1 1 1 0 UPF0524 of C3orf70 HSP70 PF00012.20 GBG85454.1 - 7.2 4.7 11.1 8.4 4.4 11.1 1.2 1 0 0 1 1 1 0 Hsp70 protein Pex26 PF07163.12 GBG85454.1 - 9.9 5.4 6.1 14 4.9 6.1 1.2 1 0 0 1 1 1 0 Pex26 protein Nodulin-like PF06813.13 GBG85457.1 - 1.3e-63 214.9 6.6 1.3e-63 214.9 6.6 2.2 2 0 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 GBG85457.1 - 1.2e-09 37.6 35.1 2.7e-08 33.2 5.1 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily zf-CCHC PF00098.23 GBG85458.1 - 0.14 12.3 1.0 0.25 11.5 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Vasculin PF15337.6 GBG85460.1 - 0.00015 22.6 1.1 0.71 10.7 0.1 2.4 2 0 0 2 2 2 2 Vascular protein family Vasculin-like 1 DUF3271 PF11675.8 GBG85460.1 - 0.0056 16.0 0.2 0.95 8.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3271) Sec16_N PF12935.7 GBG85460.1 - 0.054 13.7 1.2 9.2 6.3 0.1 2.3 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus HBS1_N PF08938.10 GBG85460.1 - 0.17 12.2 5.7 3.3 8.1 0.6 2.5 2 0 0 2 2 2 0 HBS1 N-terminus RVT_1 PF00078.27 GBG85461.1 - 8.1e-29 100.7 0.0 1.5e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG85461.1 - 2e-07 30.8 0.0 4.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG85465.1 - 1.1e-20 73.9 0.0 2.3e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85465.1 - 1.2e-18 66.9 0.0 2.4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85465.1 - 1.2e-16 60.5 2.6 2.5e-16 59.5 2.6 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85465.1 - 1.3e-15 57.6 0.0 3.9e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG85465.1 - 7.4e-06 26.4 0.1 2e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85465.1 - 0.00024 21.7 0.1 0.00061 20.4 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85465.1 - 0.00093 19.0 0.1 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85465.1 - 0.02 14.7 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG85466.1 - 0.023 14.3 0.3 0.044 13.4 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG85466.1 - 0.043 13.9 1.9 0.084 13.0 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 GBG85466.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease TetR_C_9 PF14514.6 GBG85466.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Gln-synt_C PF00120.24 GBG85467.1 - 2.3e-15 56.4 0.0 2.1e-12 46.7 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG85467.1 - 5e-11 42.2 0.0 8.2e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 GBG85470.1 - 2.3e-15 56.4 0.0 2.1e-12 46.7 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG85470.1 - 5e-11 42.2 0.0 8.2e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RVT_1 PF00078.27 GBG85471.1 - 1.3e-08 34.6 0.0 2.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PDZ_4 PF17816.1 GBG85471.1 - 0.036 14.5 0.0 0.14 12.6 0.0 1.9 1 1 0 1 1 1 0 PDZ domain Dimer_Tnp_hAT PF05699.14 GBG85473.1 - 1e-10 41.3 0.0 1e-10 41.3 0.0 2.3 2 1 1 3 3 3 1 hAT family C-terminal dimerisation region Actin PF00022.19 GBG85475.1 - 6.8e-110 367.5 0.0 3.4e-109 365.2 0.0 1.8 1 1 0 1 1 1 1 Actin RRM_1 PF00076.22 GBG85475.1 - 1.8e-08 34.1 0.1 3e-07 30.2 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.27 GBG85476.1 - 2.5e-17 63.2 0.5 2e-08 34.0 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85476.1 - 3e-11 43.2 0.0 9.3e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG85476.1 - 0.00011 22.0 0.2 0.00037 20.3 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG85476.1 - 0.0004 20.6 0.0 0.0004 20.6 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase DUF4187 PF13821.6 GBG85476.1 - 0.0027 17.4 1.1 0.0093 15.7 1.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RVP_2 PF08284.11 GBG85476.1 - 0.032 14.0 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG85476.1 - 0.12 12.7 5.3 0.48 10.7 0.2 3.8 3 0 0 3 3 3 0 Retrotransposon gag protein TadF PF16964.5 GBG85476.1 - 0.39 10.5 1.8 1.2 8.9 1.8 1.8 1 0 0 1 1 1 0 Putative tight adherence pilin protein F RT_RNaseH_2 PF17919.1 GBG85477.1 - 8.2e-34 115.6 0.0 2.3e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85477.1 - 6.2e-30 104.4 0.1 1.1e-29 103.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85477.1 - 1.3e-28 99.4 0.1 3e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85477.1 - 1.3e-18 66.9 0.1 3.2e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85477.1 - 3.4e-14 53.1 0.2 2.1e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG85477.1 - 0.025 14.8 0.0 0.11 12.7 0.0 2.2 1 0 0 1 1 1 0 H2C2 zinc finger RRM_1 PF00076.22 GBG85477.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SlyX PF04102.12 GBG85477.1 - 0.23 12.1 1.5 0.66 10.6 0.4 2.4 2 0 0 2 2 2 0 SlyX LRRNT PF01462.18 GBG85478.1 - 0.029 14.0 14.8 2.1 8.1 0.7 3.2 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain RT_RNaseH PF17917.1 GBG85479.1 - 3.1e-22 78.8 0.0 5.7e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85479.1 - 1.2e-20 73.4 0.0 3e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG85479.1 - 6.2e-08 33.1 0.0 1.8e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85479.1 - 3.8e-05 24.2 0.0 0.00012 22.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85479.1 - 0.0016 18.2 0.1 0.0041 16.9 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG85479.1 - 0.036 14.2 1.6 0.079 13.1 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.20 GBG85479.1 - 0.074 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease PCMT PF01135.19 GBG85481.1 - 1.2e-78 263.6 0.0 1.8e-78 263.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GBG85481.1 - 2.1e-06 27.6 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GBG85481.1 - 7.4e-05 22.3 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 GBG85481.1 - 0.00099 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG85481.1 - 0.0038 17.9 0.0 0.0086 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG85481.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 GBG85481.1 - 0.043 12.9 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin GCD14 PF08704.10 GBG85481.1 - 0.051 13.2 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.20 GBG85481.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 GBG85481.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 GBG85481.1 - 0.25 10.9 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 GBG85481.1 - 0.25 10.6 0.0 0.44 9.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 GBG85482.1 - 1.1e-78 263.8 0.0 1.7e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GBG85482.1 - 2e-06 27.7 0.0 3.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GBG85482.1 - 7e-05 22.4 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 GBG85482.1 - 0.00094 19.2 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG85482.1 - 0.0036 18.0 0.0 0.0081 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG85482.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 GBG85482.1 - 0.04 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin GCD14 PF08704.10 GBG85482.1 - 0.049 13.3 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.20 GBG85482.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 GBG85482.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 GBG85482.1 - 0.23 11.0 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 GBG85482.1 - 0.24 10.7 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Trypan_PARP PF05887.11 GBG85483.1 - 0.097 12.7 9.9 0.2 11.7 9.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_11 PF13086.6 GBG85483.1 - 0.34 10.7 13.8 6.7 6.4 10.4 2.4 2 1 0 2 2 2 0 AAA domain RVT_1 PF00078.27 GBG85484.1 - 9.2e-18 64.6 0.2 2.7e-17 63.0 0.2 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CHAD PF05235.14 GBG85484.1 - 0.0043 17.1 3.4 0.13 12.2 1.3 2.6 2 0 0 2 2 2 1 CHAD domain DUF2870 PF11069.8 GBG85484.1 - 0.18 12.2 1.5 0.47 10.9 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Retrotrans_gag PF03732.17 GBG85484.1 - 0.27 11.6 3.5 0.29 11.4 0.0 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein Snapin_Pallidin PF14712.6 GBG85484.1 - 0.62 10.5 10.9 0.92 10.0 0.1 3.0 3 0 0 3 3 3 0 Snapin/Pallidin RT_RNaseH_2 PF17919.1 GBG85485.1 - 5.3e-34 116.2 0.2 3.6e-32 110.4 0.1 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85485.1 - 4e-24 84.9 0.2 8.8e-23 80.6 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85485.1 - 3e-21 76.0 0.0 5.5e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85486.1 - 7.1e-27 93.4 0.0 1.3e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85486.1 - 1.9e-24 86.0 0.0 3.7e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85486.1 - 1.7e-16 60.1 1.0 4.1e-16 58.8 1.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85486.1 - 1.4e-05 25.3 0.0 3.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG85486.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Longin PF13774.6 GBG85486.1 - 0.27 11.3 0.8 14 5.8 0.2 2.9 3 0 0 3 3 3 0 Regulated-SNARE-like domain RVT_1 PF00078.27 GBG85487.1 - 0.00014 21.5 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Casc1_N PF15927.5 GBG85487.1 - 7.1 6.3 32.4 0.27 10.9 11.8 3.1 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 N-terminus RT_RNaseH_2 PF17919.1 GBG85488.1 - 1.3e-33 115.0 0.0 5.4e-33 113.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85488.1 - 1.1e-29 103.6 0.0 2.1e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85488.1 - 2.4e-28 98.5 0.1 4.8e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG85488.1 - 0.17 11.6 1.0 0.4 10.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) rve PF00665.26 GBG85489.1 - 0.00014 22.0 0.1 0.00044 20.4 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG85489.1 - 0.00039 20.3 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG85489.1 - 0.095 12.4 0.1 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) AAA_lid_3 PF17862.1 GBG85489.1 - 0.16 11.8 0.2 4 7.3 0.1 2.3 2 0 0 2 2 2 0 AAA+ lid domain RVT_1 PF00078.27 GBG85491.1 - 4.2e-28 98.4 0.1 7.9e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85491.1 - 1.4e-25 89.2 0.0 3.6e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85491.1 - 3.1e-25 88.5 0.0 8e-25 87.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85491.1 - 7.3e-19 67.6 0.5 1.8e-18 66.4 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG85491.1 - 2.8e-05 24.7 0.0 7.7e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85491.1 - 0.00031 21.2 0.0 0.0019 18.7 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG85491.1 - 0.0023 17.7 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG85491.1 - 0.0091 16.2 0.1 0.0091 16.2 0.1 3.6 4 0 0 4 4 4 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG85491.1 - 0.031 14.5 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG85492.1 - 1.6e-07 31.9 0.0 5.7e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85492.1 - 2.6e-06 27.9 0.0 8.5e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG85492.1 - 0.00062 20.0 0.0 0.0038 17.5 0.0 2.4 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG85492.1 - 0.0012 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85492.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease SNAPc19 PF15497.6 GBG85492.1 - 0.022 15.2 0.3 0.13 12.8 0.0 2.1 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 CLZ PF16526.5 GBG85492.1 - 0.12 12.7 3.2 0.098 13.0 0.6 2.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lys-AminoMut_A PF09043.11 GBG85492.1 - 0.13 10.7 0.7 0.21 10.0 0.7 1.3 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit ZapB PF06005.12 GBG85492.1 - 2.7 8.5 8.5 0.51 10.8 1.8 2.9 3 1 0 3 3 3 0 Cell division protein ZapB DUF659 PF04937.15 GBG85493.1 - 2.7e-32 111.8 0.0 4.8e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG85493.1 - 1.7e-07 30.9 0.6 3.8e-07 29.8 0.6 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PAP1 PF08601.10 GBG85493.1 - 1.8 8.2 11.9 3.9 7.1 11.9 1.5 1 0 0 1 1 1 0 Transcription factor PAP1 RT_RNaseH_2 PF17919.1 GBG85494.1 - 1.2e-32 111.9 0.0 2.2e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85494.1 - 8.9e-29 99.9 0.1 1.9e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85494.1 - 6.1e-12 45.5 0.0 1.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG85494.1 - 0.003 17.5 0.2 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG85494.1 - 0.0043 16.8 0.4 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG85495.1 - 1.3e-26 93.5 0.3 3.1e-26 92.3 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85495.1 - 4.1e-26 90.9 0.0 1.1e-25 89.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85495.1 - 1.5e-23 83.0 0.0 3.7e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85495.1 - 6e-16 58.3 1.0 1.5e-15 57.0 1.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG85495.1 - 2e-06 28.0 7.2 8.5e-05 22.8 0.0 4.0 4 0 0 4 4 4 2 Retrotransposon gag protein CLZ PF16526.5 GBG85495.1 - 0.051 13.9 6.0 0.3 11.5 0.5 4.0 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF659 PF04937.15 GBG85497.1 - 3.5e-12 46.4 0.3 1e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Histone PF00125.24 GBG85499.1 - 8.8e-15 55.2 0.7 8.8e-15 55.2 0.7 3.7 3 2 1 4 4 4 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GBG85499.1 - 0.00051 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold HMG-CoA_red PF00368.18 GBG85500.1 - 6.9e-140 466.2 5.4 8.8e-140 465.9 5.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase DUF953 PF06110.11 GBG85501.1 - 1e-33 115.5 0.0 1.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 GBG85501.1 - 0.11 12.3 0.3 0.17 11.6 0.3 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.20 GBG85501.1 - 0.15 12.1 0.6 0.6 10.1 0.6 2.0 1 1 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 GBG85501.1 - 0.41 10.9 2.4 13 6.1 0.4 2.3 1 1 1 2 2 2 0 Glutaredoxin G6PD_C PF02781.16 GBG85502.1 - 2.4e-99 332.2 0.0 3.1e-99 331.8 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GBG85502.1 - 9.1e-48 163.2 0.0 1.4e-47 162.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Rhomboid PF01694.22 GBG85503.1 - 3.5e-18 66.0 7.8 5.7e-18 65.3 7.8 1.3 1 0 0 1 1 1 1 Rhomboid family zf-RanBP PF00641.18 GBG85503.1 - 1.8e-05 24.0 1.0 2.8e-05 23.3 1.0 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF1751 PF08551.10 GBG85503.1 - 0.05 14.2 0.4 0.05 14.2 0.4 1.8 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) CDC45 PF02724.14 GBG85504.1 - 7e-05 21.3 10.0 0.00012 20.5 10.0 1.3 1 0 0 1 1 1 1 CDC45-like protein NPR3 PF03666.13 GBG85504.1 - 0.16 10.8 3.5 0.23 10.2 3.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 GBG85504.1 - 0.16 11.8 10.7 0.29 10.9 10.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 GBG85504.1 - 0.36 9.2 28.0 0.55 8.6 28.0 1.2 1 0 0 1 1 1 0 Mpp10 protein FAM178 PF14816.6 GBG85504.1 - 0.57 9.1 2.8 0.88 8.5 2.8 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 Sec62 PF03839.16 GBG85504.1 - 0.62 9.5 4.3 1.3 8.5 4.3 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_Rpc4 PF05132.14 GBG85504.1 - 0.93 9.9 3.1 6 7.3 3.7 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 PA26 PF04636.13 GBG85504.1 - 1.2 8.0 4.3 1.8 7.4 4.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TFIIF_alpha PF05793.12 GBG85504.1 - 2 6.9 31.7 0.058 12.0 23.8 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FlxA PF14282.6 GBG85504.1 - 3 7.9 8.5 5.8 7.0 8.5 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF4820 PF16091.5 GBG85504.1 - 7.6 5.8 8.8 71 2.6 8.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF740 PF05340.12 GBG85504.1 - 8.4 5.0 14.1 16 4.1 14.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Nop16 PF09420.10 GBG85504.1 - 10 6.1 12.4 23 4.9 12.4 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 CCCAP PF15964.5 GBG85506.1 - 3.6e-08 32.2 33.4 3.6e-08 32.2 33.4 4.6 4 2 0 5 5 5 2 Centrosomal colon cancer autoantigen protein family Fez1 PF06818.15 GBG85506.1 - 0.0041 17.6 10.6 0.0041 17.6 10.6 6.9 1 1 5 7 7 7 2 Fez1 Shugoshin_N PF07558.11 GBG85506.1 - 1.6 8.7 7.1 2.3 8.1 0.1 4.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region BCL_N PF04714.13 GBG85506.1 - 6.2 7.0 6.3 6.3 6.9 0.0 3.6 3 0 0 3 3 3 0 BCL7, N-terminal conserver region DUF2868 PF11067.8 GBG85507.1 - 0.97 8.9 2.9 1.4 8.3 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Borrelia_P83 PF05262.11 GBG85507.1 - 1.2 7.5 14.5 1.3 7.5 14.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PhoLip_ATPase_C PF16212.5 GBG85508.1 - 6.8e-83 278.2 24.1 6.8e-83 278.2 24.1 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GBG85508.1 - 1.2e-22 79.3 1.5 3.9e-22 77.7 1.5 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GBG85508.1 - 9.8e-12 44.8 0.0 8.8e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GBG85508.1 - 4.1e-09 37.0 0.5 0.0001 22.7 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GBG85508.1 - 2e-08 34.0 0.0 1.3e-07 31.3 0.0 2.4 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GBG85508.1 - 0.0072 16.1 0.5 0.022 14.5 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4925 PF16272.5 GBG85508.1 - 0.076 12.5 0.2 0.21 11.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4925) CDC45 PF02724.14 GBG85509.1 - 6.4e-137 457.5 4.9 3.6e-134 448.5 4.9 2.6 1 1 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 GBG85509.1 - 0.082 13.0 8.7 0.14 12.3 8.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 GBG85509.1 - 2.5 7.3 10.5 4.4 6.5 10.5 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GBG85509.1 - 4.8 7.6 14.8 10 6.6 14.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 GBG85509.1 - 8.1 4.4 9.3 11 3.9 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Serinc PF03348.15 GBG85510.1 - 0.0085 15.1 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) BUD22 PF09073.10 GBG85510.1 - 0.028 13.8 18.5 0.038 13.4 18.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG85510.1 - 0.12 11.7 22.6 0.16 11.3 22.6 1.1 1 0 0 1 1 1 0 SDA1 IFT57 PF10498.9 GBG85510.1 - 0.66 8.9 13.8 0.85 8.5 13.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nop14 PF04147.12 GBG85510.1 - 1 7.5 26.1 1.4 7.1 26.1 1.1 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 GBG85510.1 - 2 7.2 6.7 2.4 6.9 6.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 GBG85510.1 - 2 6.6 24.8 2.8 6.1 24.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_6 PF12697.7 GBG85512.1 - 4e-20 73.4 2.4 4e-20 73.4 2.4 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG85512.1 - 2.9e-18 66.5 0.0 1.3e-16 61.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG85512.1 - 4e-06 26.3 0.0 1.2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 MENTAL PF10457.9 GBG85512.1 - 0.017 14.9 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Cholesterol-capturing domain Ser_hydrolase PF06821.13 GBG85512.1 - 0.027 14.3 0.0 0.076 12.9 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Ndr PF03096.14 GBG85512.1 - 0.14 10.8 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Ndr family zf-RVT PF13966.6 GBG85514.1 - 3.3e-06 27.7 1.2 3.3e-06 27.7 1.2 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Chlam_PMP PF02415.17 GBG85514.1 - 0.0003 21.1 34.6 1.5 9.4 0.3 6.7 6 1 0 6 6 6 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RT_RNaseH_2 PF17919.1 GBG85515.1 - 2.3e-29 101.4 0.0 1.7e-15 56.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85515.1 - 1.7e-27 95.8 0.0 3.6e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85515.1 - 1.1e-25 90.5 0.0 1.9e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG85515.1 - 1.6e-17 63.7 0.0 2.6e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG85515.1 - 3.5e-14 52.7 0.1 8.2e-14 51.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85515.1 - 4.1e-06 27.0 0.0 2.4e-05 24.5 0.0 2.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85515.1 - 0.0075 16.5 0.1 0.024 14.9 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DLEU7 PF15760.5 GBG85516.1 - 0.29 10.6 4.9 0.14 11.7 2.5 1.7 1 1 0 1 1 1 0 Leukemia-associated protein 7 Nop14 PF04147.12 GBG85517.1 - 3.3 5.8 14.4 0.045 12.0 6.9 1.5 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 GBG85517.1 - 3.4 5.9 11.3 4.7 5.4 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein PRP1_N PF06424.12 GBG85517.1 - 7.5 6.9 13.8 0.67 10.3 8.5 1.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal SAM_1 PF00536.30 GBG85518.1 - 5.4e-08 33.2 0.0 9.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GBG85518.1 - 7.9e-07 29.1 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_1 PF00036.32 GBG85518.1 - 0.0048 16.4 0.0 0.06 12.9 0.0 2.3 2 0 0 2 2 2 1 EF hand FYVE PF01363.21 GBG85518.1 - 0.023 14.8 15.0 0.071 13.3 15.0 1.8 1 0 0 1 1 1 0 FYVE zinc finger EF-hand_6 PF13405.6 GBG85518.1 - 0.061 13.3 0.0 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 GBG85518.1 - 0.21 11.1 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 EF hand SAM_1 PF00536.30 GBG85519.1 - 5.5e-08 33.1 0.0 9.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GBG85519.1 - 8.1e-07 29.1 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_1 PF00036.32 GBG85519.1 - 0.0049 16.3 0.0 0.061 12.9 0.0 2.3 2 0 0 2 2 2 1 EF hand FYVE PF01363.21 GBG85519.1 - 0.024 14.8 15.0 0.072 13.2 15.0 1.8 1 0 0 1 1 1 0 FYVE zinc finger EF-hand_6 PF13405.6 GBG85519.1 - 0.062 13.3 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 GBG85519.1 - 0.22 11.1 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 EF hand RT_RNaseH PF17917.1 GBG85520.1 - 4.1e-23 81.7 0.0 3.2e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85520.1 - 4.8e-22 77.9 0.0 1.3e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG85520.1 - 2.1e-08 34.6 0.0 4.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG85520.1 - 2.1e-06 27.4 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG85520.1 - 2.5e-06 28.0 0.0 5.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85520.1 - 0.0024 17.7 0.3 0.0047 16.7 0.3 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85520.1 - 0.015 15.6 0.0 0.039 14.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 GBG85520.1 - 0.13 12.5 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Pkinase PF00069.25 GBG85521.1 - 2.2e-40 138.7 0.0 3.2e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG85521.1 - 3.5e-36 124.8 0.0 8.5e-36 123.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 GBG85521.1 - 0.013 15.7 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 ABC1 family SGL PF08450.12 GBG85521.1 - 0.014 15.0 0.1 3.8 7.0 0.0 2.5 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Pkinase_fungal PF17667.1 GBG85521.1 - 0.03 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RT_RNaseH_2 PF17919.1 GBG85522.1 - 3.1e-33 113.8 0.0 5.5e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85522.1 - 4.4e-30 104.9 0.0 6.8e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85522.1 - 1.7e-27 95.7 0.0 3.3e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5095 PF17016.5 GBG85522.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) gag-asp_proteas PF13975.6 GBG85523.1 - 1e-07 32.4 0.1 2.7e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85523.1 - 2.1e-06 28.3 0.0 6.2e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85523.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85523.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG85523.1 - 0.084 12.6 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like CsgE PF10627.9 GBG85525.1 - 6.3 7.1 11.2 0.33 11.2 5.2 2.0 2 1 0 2 2 2 0 Curli assembly protein CsgE Nop14 PF04147.12 GBG85526.1 - 2.5 6.2 22.3 3.1 5.9 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG85526.1 - 7.9 5.9 11.5 4.7 6.7 9.9 1.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist LPP20 PF02169.16 GBG85527.1 - 0.16 12.3 0.1 0.44 10.9 0.1 1.7 1 0 0 1 1 1 0 LPP20 lipoprotein FHA PF00498.26 GBG85530.1 - 2.7e-06 27.6 0.0 5.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain FlaC_arch PF05377.11 GBG85530.1 - 0.15 12.5 6.6 0.44 11.0 0.7 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 GBG85530.1 - 0.42 10.9 6.7 0.5 10.7 4.1 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein Helicase_C PF00271.31 GBG85531.1 - 1.7e-12 47.6 0.0 4.3e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GBG85531.1 - 0.047 12.8 1.2 0.079 12.1 0.2 2.1 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 RRN3 PF05327.11 GBG85532.1 - 3.1 6.2 7.9 4.3 5.8 7.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Integrase_H2C2 PF17921.1 GBG85533.1 - 3.5e-16 59.1 0.3 3.5e-16 59.1 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain SNF2_N PF00176.23 GBG85533.1 - 8.4e-14 51.0 0.1 4.3e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain RT_RNaseH PF17917.1 GBG85533.1 - 1.5e-12 47.7 0.2 3.2e-12 46.6 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85533.1 - 2.1e-07 30.9 0.0 5.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG85533.1 - 0.00053 20.1 0.2 0.0013 18.9 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG85533.1 - 0.0035 17.2 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PDEase_II PF02112.15 GBG85533.1 - 0.041 13.0 0.2 0.068 12.3 0.2 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II SGIII PF15467.6 GBG85533.1 - 0.048 12.9 0.2 0.048 12.9 0.2 1.5 2 0 0 2 2 2 0 Secretogranin-3 Integrase_H2C2 PF17921.1 GBG85534.1 - 7.5e-15 54.8 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG85534.1 - 3.2e-12 46.7 0.3 8.7e-12 45.3 0.3 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85534.1 - 4e-08 33.5 0.1 1e-07 32.2 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG85534.1 - 0.0022 18.0 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CNOT1_HEAT_N PF16419.5 GBG85534.1 - 0.076 12.7 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Asp_protease_2 PF13650.6 GBG85535.1 - 7.3e-06 26.5 0.0 1.9e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85535.1 - 0.00014 21.6 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG85535.1 - 0.00024 21.6 0.0 0.00071 20.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2408 PF10303.9 GBG85535.1 - 0.023 15.2 0.2 0.055 14.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Asp_protease PF09668.10 GBG85535.1 - 0.031 14.1 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease GSHPx PF00255.19 GBG85535.1 - 0.14 11.7 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione peroxidase DUF4219 PF13961.6 GBG85535.1 - 0.14 11.8 0.5 12 5.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) SNF2_N PF00176.23 GBG85536.1 - 1.5e-13 50.2 0.3 3.5e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 GBG85536.1 - 0.11 12.4 0.1 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PRIMA1 PF16101.5 GBG85537.1 - 0.21 11.6 5.4 1 9.4 1.8 2.7 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 CRAL_TRIO_2 PF13716.6 GBG85538.1 - 1.2e-16 61.1 0.1 1.7e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GBG85538.1 - 0.0035 17.1 1.0 0.01 15.6 1.0 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GBG85539.1 - 1e-17 64.6 0.1 1.5e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GBG85539.1 - 0.0037 17.0 1.1 0.01 15.6 1.1 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain IATP PF04568.12 GBG85539.1 - 5.8 7.4 9.9 5.2 7.6 0.6 3.4 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP CDC45 PF02724.14 GBG85540.1 - 1.2 7.4 4.4 1.5 7.0 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein FlaC_arch PF05377.11 GBG85541.1 - 0.0056 17.0 1.5 0.19 12.1 0.1 2.7 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) SlyX PF04102.12 GBG85541.1 - 0.0084 16.7 0.5 0.039 14.6 0.2 2.3 1 1 1 2 2 2 1 SlyX ZapB PF06005.12 GBG85541.1 - 0.0085 16.5 3.1 0.026 15.0 3.1 2.0 1 0 0 1 1 1 1 Cell division protein ZapB TSC22 PF01166.18 GBG85541.1 - 0.0094 16.2 1.2 0.028 14.7 1.2 1.9 1 0 0 1 1 1 1 TSC-22/dip/bun family LPP PF04728.13 GBG85541.1 - 0.036 14.4 0.4 0.12 12.8 0.4 2.0 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Syntaxin_2 PF14523.6 GBG85541.1 - 0.082 13.3 3.0 0.15 12.4 1.5 2.2 1 1 1 2 2 2 0 Syntaxin-like protein Allexi_40kDa PF05549.11 GBG85541.1 - 0.39 10.2 3.8 0.25 10.8 2.0 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein Spc7 PF08317.11 GBG85541.1 - 0.46 9.3 9.7 0.064 12.1 3.5 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 GBG85541.1 - 0.64 10.1 9.1 0.06 13.4 2.1 2.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 GBG85541.1 - 1.1 9.9 4.7 0.59 10.8 1.2 2.2 2 0 0 2 2 2 0 Initiation control protein YabA ORF6C PF10552.9 GBG85541.1 - 3.7 7.7 6.8 0.41 10.8 1.1 2.1 2 1 0 2 2 2 0 ORF6C domain DUF4201 PF13870.6 GBG85541.1 - 4.8 6.9 12.0 0.064 13.0 3.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Fez1 PF06818.15 GBG85541.1 - 10 6.5 16.7 0.91 9.9 6.3 2.1 1 1 0 2 2 2 0 Fez1 RVP_2 PF08284.11 GBG85542.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Acyltransferase PF01553.21 GBG85543.1 - 0.016 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase Acyltransf_C PF16076.5 GBG85545.1 - 1.8e-19 69.6 0.0 3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 GBG85545.1 - 1.6e-05 24.5 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF4191 PF13829.6 GBG85545.1 - 0.01 15.2 1.0 0.018 14.4 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FGGY_N PF00370.21 GBG85546.1 - 2.1e-34 119.2 0.0 2.9e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GBG85546.1 - 4.3e-22 78.8 0.0 1e-21 77.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4189 PF13827.6 GBG85546.1 - 0.087 13.4 2.2 3.2 8.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4189) Methyltransf_5 PF01795.19 GBG85547.1 - 2.7e-69 234.0 0.1 1.8e-24 86.8 0.0 5.1 4 1 1 5 5 5 5 MraW methylase family DUF2710 PF10921.8 GBG85547.1 - 0.68 10.4 3.3 5.2 7.5 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2710) BET PF17035.5 GBG85548.1 - 1.8e-09 37.6 0.3 3.1e-09 36.9 0.3 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF5352 PF17303.2 GBG85549.1 - 0.24 11.2 3.0 0.2 11.5 0.3 2.1 2 1 1 3 3 3 0 Family of unknown function (DUF5352) BRI3BP PF14965.6 GBG85549.1 - 0.62 9.6 3.3 52 3.3 0.9 3.0 3 0 0 3 3 3 0 Negative regulator of p53/TP53 RVT_1 PF00078.27 GBG85550.1 - 4.8e-08 32.8 0.0 9.5e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG85550.1 - 1.9e-06 28.3 0.3 6.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85550.1 - 2e-06 28.3 0.1 1.3e-05 25.8 0.0 2.5 3 0 0 3 3 3 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG85550.1 - 4.6e-05 23.4 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85550.1 - 8.6e-05 22.8 0.3 0.00031 21.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG85550.1 - 0.019 14.8 1.3 0.039 13.8 1.3 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_4 PF14392.6 GBG85550.1 - 0.087 12.6 0.5 0.24 11.2 0.5 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF3347 PF11827.8 GBG85550.1 - 1.3 9.2 5.9 0.17 12.1 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) La PF05383.17 GBG85553.1 - 2.5e-21 75.5 0.2 4e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 La domain La PF05383.17 GBG85554.1 - 2.5e-21 75.5 0.2 3.9e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 La domain Voldacs PF03517.13 GBG85556.1 - 3.2e-22 79.1 0.0 3.2e-22 79.1 0.0 1.5 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 GBG85556.1 - 2e-05 24.7 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 F-box-like PF12937.7 GBG85557.1 - 0.0019 18.0 0.3 0.006 16.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG85557.1 - 0.034 14.0 1.5 0.39 10.6 0.0 2.7 2 0 0 2 2 2 0 F-box domain ATG_C PF09333.11 GBG85558.1 - 8e-14 51.8 0.6 2.5e-05 24.5 0.0 3.1 3 0 0 3 3 3 2 Autophagy-related protein C terminal domain VPS13_C PF16909.5 GBG85558.1 - 4.7e-05 23.2 2.6 0.05 13.4 0.2 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal RVT_1 PF00078.27 GBG85559.1 - 1.8e-27 96.3 0.1 3.2e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85559.1 - 9.7e-25 86.5 0.0 1.9e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85559.1 - 9.9e-22 77.2 0.0 3.4e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85559.1 - 1.5e-08 34.6 0.1 4.2e-08 33.2 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG85559.1 - 3.6e-07 30.6 0.0 7.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85559.1 - 4.4e-06 27.2 0.0 1.1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85559.1 - 6.5e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85559.1 - 0.00019 21.2 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF4187 PF13821.6 GBG85559.1 - 0.002 17.9 0.4 0.007 16.1 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG85559.1 - 0.0038 17.5 0.1 0.016 15.4 0.1 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG85560.1 - 1.3e-27 96.7 0.0 2.4e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85560.1 - 2.4e-25 88.5 0.0 7.7e-25 86.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85560.1 - 7.8e-24 84.0 0.0 2.6e-23 82.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG85560.1 - 5.8e-07 30.1 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85560.1 - 3.8e-06 27.4 0.0 9.6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG85560.1 - 7.8e-06 25.7 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85560.1 - 0.0002 21.1 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG85560.1 - 0.0019 18.3 0.0 0.0061 16.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG85560.1 - 0.0021 18.3 0.4 0.0086 16.3 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG85560.1 - 0.012 15.5 0.0 0.035 14.0 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG85561.1 - 2.3e-22 79.6 0.1 6.1e-22 78.2 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG85561.1 - 0.075 13.3 0.5 0.075 13.3 0.5 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG85562.1 - 2.6e-27 95.8 0.1 2e-26 92.9 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85562.1 - 1.3e-18 67.2 0.0 5e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85562.1 - 1.5e-14 53.8 0.0 6.4e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85562.1 - 1.3e-10 41.2 0.4 1.3e-10 41.2 0.4 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG85562.1 - 3.2e-05 24.4 0.0 5.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85562.1 - 9.3e-05 23.0 0.0 0.00017 22.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85562.1 - 0.00016 21.4 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85562.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF928 PF06051.12 GBG85563.1 - 0.015 15.2 2.1 0.33 10.8 0.1 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF928) SlyX PF04102.12 GBG85564.1 - 0.0058 17.2 0.4 0.22 12.2 0.0 2.5 2 0 0 2 2 2 1 SlyX Gon7 PF08738.10 GBG85564.1 - 0.014 15.4 2.4 0.025 14.6 0.3 2.3 1 1 0 2 2 2 0 Gon7 family Phage_GP20 PF06810.11 GBG85564.1 - 0.035 13.9 1.9 0.042 13.7 1.0 1.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Cnn_1N PF07989.11 GBG85564.1 - 0.074 13.2 1.5 7 6.9 0.0 2.7 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 GBG85564.1 - 0.21 12.0 0.2 9.4 6.7 0.0 2.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 GBG85564.1 - 0.26 10.6 10.0 0.1 12.0 7.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Adaptin_binding PF10199.9 GBG85564.1 - 2.5 8.7 7.8 12 6.5 7.8 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 rve PF00665.26 GBG85565.1 - 1.1e-10 41.7 0.0 4.6e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG85565.1 - 0.03 15.0 0.0 0.078 13.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG85565.1 - 0.068 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease gag-asp_proteas PF13975.6 GBG85567.1 - 1.5e-07 31.9 0.6 3.1e-06 27.7 0.0 3.0 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85567.1 - 3.2e-06 27.7 0.0 1.5e-05 25.6 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85567.1 - 0.017 15.4 0.0 0.051 13.9 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG85567.1 - 0.019 15.2 5.3 0.04 14.2 0.0 3.7 4 1 0 4 4 4 0 Retrotransposon gag protein IMD PF08397.11 GBG85567.1 - 0.078 12.3 1.1 4 6.7 0.0 2.5 2 0 0 2 2 2 0 IRSp53/MIM homology domain ParE_toxin PF05016.15 GBG85567.1 - 0.17 12.5 2.7 26 5.5 0.5 3.3 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE PS_Dcarbxylase PF02666.15 GBG85568.1 - 1.1e-61 207.9 0.0 2.7e-61 206.6 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase RT_RNaseH_2 PF17919.1 GBG85569.1 - 2.1e-29 101.5 0.0 1.3e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85569.1 - 5.2e-29 100.6 0.0 1.1e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85569.1 - 7.3e-14 51.6 0.0 1.5e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85569.1 - 1.5e-08 34.4 0.0 5.1e-05 22.9 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG85569.1 - 0.047 13.9 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger LMBR1 PF04791.16 GBG85570.1 - 6.1e-70 236.6 7.8 6.9e-46 157.2 0.5 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein TMEM237 PF15383.6 GBG85570.1 - 0.088 11.9 3.3 0.18 10.9 3.3 1.5 1 0 0 1 1 1 0 Transmembrane protein 237 S1FA PF04689.13 GBG85570.1 - 3 8.1 5.9 11 6.3 0.7 3.7 3 0 0 3 3 3 0 DNA binding protein S1FA DUF4307 PF14155.6 GBG85570.1 - 4.4 7.2 7.6 20 5.0 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) RVT_1 PF00078.27 GBG85571.1 - 2.7e-32 112.1 0.0 4.2e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG85571.1 - 2.2e-15 56.5 0.8 6.6e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG85571.1 - 8.4e-13 48.6 0.0 2.2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85571.1 - 1.6e-05 25.0 0.0 4.8e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger SPATIAL PF15256.6 GBG85571.1 - 0.21 11.9 1.6 0.38 11.1 1.6 1.4 1 0 0 1 1 1 0 SPATIAL FoP_duplication PF13865.6 GBG85572.1 - 2e-09 37.9 8.0 2e-09 37.9 8.0 5.5 4 1 0 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 DUF659 PF04937.15 GBG85574.1 - 0.0038 17.1 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) NIF PF03031.18 GBG85575.1 - 0.0095 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NIF PF03031.18 GBG85576.1 - 3.2e-08 33.5 0.0 4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RT_RNaseH_2 PF17919.1 GBG85577.1 - 6.4e-24 83.9 0.0 1.6e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85577.1 - 2.5e-22 79.1 0.0 6.8e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85577.1 - 3.1e-10 39.9 0.0 6.9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG85577.1 - 0.02 15.2 7.3 0.043 14.1 0.1 3.9 4 0 0 4 4 3 0 Retrotransposon gag protein Glycos_transf_3 PF00591.21 GBG85577.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, a/b domain Longin PF13774.6 GBG85577.1 - 0.14 12.2 0.4 11 6.1 0.2 3.1 2 0 0 2 2 2 0 Regulated-SNARE-like domain SPARC_Ca_bdg PF10591.9 GBG85577.1 - 0.16 12.3 0.7 0.44 10.9 0.7 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3006 PF11213.8 GBG85577.1 - 0.22 11.8 2.1 0.68 10.2 2.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) HIP1_clath_bdg PF16515.5 GBG85577.1 - 0.48 11.1 19.1 0.023 15.3 4.6 3.2 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LMBR1 PF04791.16 GBG85577.1 - 1.2 8.0 3.2 2 7.2 3.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 GBG85577.1 - 5.3 6.3 16.7 4.7 6.5 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 GBG85579.1 - 1.6e-35 122.7 0.0 2.8e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG85579.1 - 2e-35 122.4 0.0 4.4e-35 121.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG85579.1 - 0.034 14.1 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Retrotrans_gag PF03732.17 GBG85579.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein CDV3 PF15359.6 GBG85582.1 - 2.7 8.5 9.1 0.17 12.4 2.8 2.1 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Retrotrans_gag PF03732.17 GBG85583.1 - 0.00021 21.5 0.4 0.00056 20.1 0.3 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein DUF4211 PF13926.6 GBG85583.1 - 0.059 13.4 0.8 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Integrase_H2C2 PF17921.1 GBG85584.1 - 2.5e-13 49.9 0.1 5.3e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG85584.1 - 1.1e-07 32.3 0.0 2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85584.1 - 1.6e-05 25.5 0.0 3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG85584.1 - 0.0004 20.6 0.0 0.00079 19.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG85584.1 - 0.0026 17.6 0.3 0.0045 16.8 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85584.1 - 0.0082 16.4 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG85584.1 - 0.048 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG85585.1 - 4.3e-35 121.2 0.1 6.5e-35 120.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85585.1 - 6.5e-15 55.0 0.0 1.7e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85585.1 - 0.0002 21.6 0.0 0.0005 20.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Yop-YscD_ppl PF16693.5 GBG85585.1 - 0.11 12.0 0.1 42 3.4 0.0 3.2 3 0 0 3 3 3 0 Inner membrane component of T3SS, periplasmic domain Cep57_CLD_2 PF14197.6 GBG85587.1 - 0.0094 16.0 9.0 0.43 10.7 0.4 3.5 3 0 0 3 3 3 2 Centrosome localisation domain of PPC89 DUF413 PF04219.12 GBG85587.1 - 3.1 7.9 6.0 1.2 9.2 0.7 2.9 4 1 0 4 4 4 0 Protein of unknown function, DUF DUF5320 PF17253.2 GBG85587.1 - 3.2 8.9 7.6 0.41 11.7 0.8 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5320) PHM7_cyt PF14703.6 GBG85587.1 - 4.9 7.3 12.4 0.098 12.9 3.2 2.2 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Prefoldin PF02996.17 GBG85587.1 - 6.3 6.7 15.1 0.058 13.3 2.0 3.3 4 0 0 4 4 4 0 Prefoldin subunit Integrase_H2C2 PF17921.1 GBG85588.1 - 2.6e-15 56.3 0.7 1.1e-14 54.3 0.1 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG85588.1 - 5.4e-07 29.8 0.0 1.5e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG85588.1 - 3.8e-06 27.4 0.1 1.1e-05 25.9 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG85588.1 - 0.012 15.8 0.0 0.036 14.3 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG85588.1 - 0.019 15.6 0.0 0.057 14.1 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG85588.1 - 0.026 14.8 0.1 0.085 13.1 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG85588.1 - 0.027 14.3 0.5 0.051 13.4 0.5 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF702 PF05142.12 GBG85590.1 - 8.9e-46 156.1 0.3 1.3e-45 155.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF702) DUF702 PF05142.12 GBG85591.1 - 4.7e-46 157.0 0.3 6.5e-46 156.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF702) RT_RNaseH_2 PF17919.1 GBG85592.1 - 2.8e-33 113.9 0.0 6.9e-17 61.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85592.1 - 4.9e-31 107.1 0.0 9.7e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85592.1 - 1.5e-28 99.9 0.1 2.5e-28 99.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IncFII_repA PF02387.15 GBG85593.1 - 0.019 14.2 6.2 0.027 13.7 6.2 1.2 1 0 0 1 1 1 0 IncFII RepA protein family DUF4375 PF14300.6 GBG85593.1 - 0.15 12.4 4.1 0.29 11.4 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Ebp2 PF05890.12 GBG85593.1 - 0.33 10.5 19.2 0.6 9.6 19.2 1.3 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 DUF4607 PF15380.6 GBG85593.1 - 0.41 10.1 5.4 0.1 12.0 1.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4607) Retrotrans_gag PF03732.17 GBG85594.1 - 5.6e-05 23.3 1.0 0.00032 20.9 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG85594.1 - 0.011 15.5 2.0 0.011 15.5 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) DivIC PF04977.15 GBG85594.1 - 0.12 12.2 0.3 0.12 12.2 0.3 2.8 2 1 0 2 2 2 0 Septum formation initiator Golgin_A5 PF09787.9 GBG85594.1 - 0.41 10.1 11.6 0.63 9.4 11.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 GBG85594.1 - 1.5 9.0 5.5 1.2 9.3 2.2 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RT_RNaseH_2 PF17919.1 GBG85595.1 - 2e-28 98.3 0.0 6.1e-28 96.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85595.1 - 2.2e-27 95.4 0.0 7.6e-27 93.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85595.1 - 1.4e-11 44.3 0.0 3.6e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85595.1 - 7.1e-11 42.0 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG85595.1 - 0.17 11.5 0.0 0.17 11.5 0.0 2.9 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2950 PF11453.8 GBG85595.1 - 5.6 6.1 10.9 4.6 6.4 9.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2950) Glyco_hydro_17 PF00332.18 GBG85596.1 - 1.2e-56 192.6 0.0 1.4e-56 192.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.13 GBG85596.1 - 1.7e-15 57.4 2.6 3e-15 56.7 2.6 1.4 1 0 0 1 1 1 1 X8 domain Glyco_hydro_17 PF00332.18 GBG85597.1 - 6.1e-60 203.4 0.1 7.5e-60 203.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.13 GBG85597.1 - 1.6e-15 57.5 0.5 2.7e-15 56.8 0.5 1.4 1 0 0 1 1 1 1 X8 domain Glyco_hydro_17 PF00332.18 GBG85598.1 - 4e-44 151.5 0.0 5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Roc PF08477.13 GBG85599.1 - 5.6e-06 26.6 0.0 1.8e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DLIC PF05783.11 GBG85599.1 - 0.00053 19.0 2.5 0.003 16.5 0.1 3.0 2 1 0 2 2 2 1 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 GBG85599.1 - 0.027 14.6 0.0 0.076 13.1 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_32 PF13654.6 GBG85599.1 - 0.062 12.1 0.0 0.089 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 GBG85599.1 - 0.17 11.4 0.0 0.41 10.2 0.0 1.8 1 1 0 1 1 1 0 Ras family K_channel_TID PF07941.11 GBG85599.1 - 3.7 8.1 17.5 1.3 9.5 13.5 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain IQ PF00612.27 GBG85600.1 - 1.1e-05 24.7 21.4 0.0018 17.9 1.8 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Mlh1_C PF16413.5 GBG85600.1 - 0.11 11.8 0.4 0.27 10.6 0.4 1.7 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus Glyco_transf_10 PF00852.19 GBG85601.1 - 4.3e-23 81.9 0.0 1.2e-22 80.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Exostosin PF03016.15 GBG85601.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Exostosin family RVT_1 PF00078.27 GBG85602.1 - 5.8e-25 88.1 0.0 9.6e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85603.1 - 1.2e-20 73.8 0.0 2.3e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85603.1 - 7.3e-19 67.7 0.0 1.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85603.1 - 7.5e-15 54.8 0.3 2.4e-14 53.2 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85603.1 - 8.3e-12 45.3 0.0 2.2e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG85603.1 - 2.7e-07 30.3 0.0 5.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG85603.1 - 0.082 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC_5 PF14787.6 GBG85603.1 - 1.5 8.6 4.3 3.3 7.5 4.3 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG85603.1 - 1.5 9.0 4.6 3.7 7.8 4.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG85604.1 - 9.4e-15 54.5 1.0 1.8e-14 53.5 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85604.1 - 2.5e-08 33.7 0.0 5.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG85604.1 - 0.075 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Sel1 PF08238.12 GBG85605.1 - 4.4e-06 27.2 1.3 0.069 13.9 0.0 2.5 2 0 0 2 2 2 2 Sel1 repeat MDM1 PF15501.6 GBG85605.1 - 2.1 7.4 37.2 0.023 13.9 9.0 2.1 2 0 0 2 2 2 0 Nuclear protein MDM1 Pox_Ag35 PF03286.14 GBG85605.1 - 2.7 7.7 30.3 2.6 7.8 9.2 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RVT_1 PF00078.27 GBG85606.1 - 9.2e-34 116.9 0.1 1.6e-33 116.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sel1 PF08238.12 GBG85606.1 - 9.5e-30 102.4 11.4 3.5e-07 30.7 0.1 6.7 7 0 0 7 7 7 4 Sel1 repeat RT_RNaseH_2 PF17919.1 GBG85606.1 - 2.2e-28 98.2 0.0 8.9e-28 96.3 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85606.1 - 2.9e-27 95.0 0.0 1.3e-26 92.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85606.1 - 1.7e-18 66.9 0.0 3.1e-17 62.9 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG85606.1 - 1.2e-14 54.2 0.1 3.1e-14 52.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG85606.1 - 0.00014 22.0 0.0 0.00053 20.2 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG85606.1 - 0.019 14.6 2.0 2 8.0 0.0 2.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase tRNA_lig_CPD PF08302.11 GBG85606.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain NCBP3 PF10309.9 GBG85608.1 - 3.3e-06 26.9 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 DUF521 PF04412.13 GBG85609.1 - 0.068 11.9 0.1 0.08 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Apt1 PF10351.9 GBG85610.1 - 1.8e-08 33.7 0.0 1.8e-08 33.7 0.0 2.3 1 1 1 2 2 2 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 GBG85610.1 - 0.00046 20.3 0.1 0.0055 16.8 0.1 2.5 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain SDA1 PF05285.12 GBG85610.1 - 0.16 11.3 49.4 0.28 10.5 49.4 1.3 1 0 0 1 1 1 0 SDA1 Integrase_H2C2 PF17921.1 GBG85611.1 - 6e-17 61.5 0.1 1.1e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG85611.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) rve PF00665.26 GBG85611.1 - 0.0032 17.6 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG85611.1 - 0.026 14.7 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger DUF659 PF04937.15 GBG85612.1 - 1.2e-32 112.9 0.1 2.6e-32 111.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG85612.1 - 0.022 14.6 0.2 0.061 13.1 0.2 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Phage_T4_gp19 PF06841.12 GBG85612.1 - 0.055 13.3 0.5 8.4 6.3 0.0 2.7 2 1 0 2 2 2 0 T4-like virus tail tube protein gp19 Apt1 PF10351.9 GBG85613.1 - 6e-21 74.9 1.1 6e-21 74.9 1.1 2.9 2 2 0 2 2 2 1 Golgi-body localisation protein domain RRM_1 PF00076.22 GBG85615.1 - 7e-39 131.5 0.0 1.3e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG85615.1 - 4.8e-07 29.8 0.0 0.05 13.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 GBG85615.1 - 1.6e-05 24.5 0.0 0.08 12.5 0.0 2.2 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipase_3 PF01764.25 GBG85616.1 - 8.3e-55 184.6 0.0 1.4e-26 93.0 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) DUF2974 PF11187.8 GBG85616.1 - 1.2e-05 25.0 0.0 2.8 7.5 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 GBG85616.1 - 0.00019 22.1 0.0 0.82 10.2 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thioesterase PF00975.20 GBG85616.1 - 0.0005 20.2 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 2 Thioesterase domain DNA_binding_1 PF01035.20 GBG85616.1 - 0.0045 17.1 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Hydrolase_4 PF12146.8 GBG85616.1 - 0.0063 15.8 0.0 3.9 6.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 GBG85616.1 - 0.017 14.9 0.0 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 GBG85616.1 - 0.035 13.7 0.0 37 3.8 0.0 3.2 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase CARD PF00619.21 GBG85616.1 - 0.1 12.7 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Caspase recruitment domain Tektin PF03148.14 GBG85616.1 - 0.32 9.7 0.3 7.2 5.2 0.0 2.0 2 0 0 2 2 2 0 Tektin family Lipase_3 PF01764.25 GBG85617.1 - 1.3e-25 90.0 0.0 2.3e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GBG85617.1 - 0.097 12.2 0.0 4.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Chlam_PMP PF02415.17 GBG85618.1 - 7.5e-08 32.4 11.9 0.45 11.1 0.1 5.3 4 0 0 4 4 4 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RVT_1 PF00078.27 GBG85619.1 - 3.7e-32 111.6 0.1 7.6e-32 110.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85619.1 - 1.8e-31 108.1 0.0 3.4e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85619.1 - 1.7e-29 102.1 0.3 3.8e-29 101.1 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85619.1 - 2.1e-18 66.1 0.0 5.5e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85619.1 - 7.1e-15 55.2 0.0 2.9e-14 53.3 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85619.1 - 0.0067 16.6 0.0 0.023 14.9 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger BTRD1 PF17660.1 GBG85619.1 - 0.023 14.5 0.0 8 6.4 0.1 2.7 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 PDZ PF00595.24 GBG85619.1 - 0.029 14.7 0.1 0.062 13.7 0.1 1.5 1 0 0 1 1 1 0 PDZ domain RRM_2 PF04059.12 GBG85620.1 - 1.1e-32 112.1 0.3 1.6e-31 108.3 0.3 2.2 1 1 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 GBG85620.1 - 8.7e-16 57.5 0.0 1.2e-09 37.9 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG85620.1 - 0.0014 18.4 0.0 0.0098 15.7 0.0 2.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 GBG85620.1 - 0.0035 16.9 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1564 PF07600.11 GBG85621.1 - 0.00065 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) zf-CCHC PF00098.23 GBG85622.1 - 0.00079 19.4 4.3 0.00079 19.4 4.3 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG85622.1 - 0.13 12.0 0.5 0.36 10.6 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG85622.1 - 1.5 8.8 4.7 2.9 7.8 4.7 1.5 1 0 0 1 1 1 0 Zinc knuckle HSP70 PF00012.20 GBG85622.1 - 5.1 5.2 13.9 8.6 4.4 13.9 1.3 1 0 0 1 1 1 0 Hsp70 protein Phage_SSB PF16773.5 GBG85623.1 - 0.024 14.7 0.3 0.049 13.7 0.3 1.4 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein RT_RNaseH_2 PF17919.1 GBG85625.1 - 3.2e-26 91.3 0.0 8.5e-26 89.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85625.1 - 1.5e-25 89.5 0.0 4.9e-25 87.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85625.1 - 2.7e-21 76.1 0.2 7.8e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG85625.1 - 1e-08 35.4 0.0 3.9e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG85625.1 - 0.0002 21.1 0.0 0.00056 19.7 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Retrotrans_gag PF03732.17 GBG85625.1 - 0.0037 17.5 0.2 0.0037 17.5 0.2 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG85625.1 - 0.026 14.4 0.0 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG85626.1 - 0.0033 17.7 0.4 0.026 14.8 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF919 PF06034.11 GBG85626.1 - 0.035 13.9 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF4932 PF16286.5 GBG85626.1 - 0.067 12.5 0.4 0.17 11.1 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4932) TPR_12 PF13424.6 GBG85627.1 - 4.6e-12 46.0 15.9 1.5e-06 28.4 0.6 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat zf-MYND PF01753.18 GBG85627.1 - 6.8e-08 32.5 12.5 1.6e-07 31.3 12.5 1.6 1 0 0 1 1 1 1 MYND finger TPR_1 PF00515.28 GBG85627.1 - 9.4e-08 31.6 4.3 1.6 8.7 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 GBG85627.1 - 3.1e-06 27.4 0.0 7.7e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ANAPC3 PF12895.7 GBG85627.1 - 9e-06 25.8 0.0 0.00015 21.9 0.0 2.7 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Acetyltransf_7 PF13508.7 GBG85627.1 - 1.2e-05 25.7 0.0 3.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_8 PF13181.6 GBG85627.1 - 9e-05 22.4 8.7 0.068 13.4 0.0 4.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG85627.1 - 0.0003 20.7 7.0 13 6.2 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat FR47 PF08445.10 GBG85627.1 - 0.0015 18.5 0.1 0.0092 15.9 0.0 2.4 3 0 0 3 3 2 1 FR47-like protein TPR_7 PF13176.6 GBG85627.1 - 0.0023 17.8 0.4 0.38 10.9 0.1 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat Acetyltransf_10 PF13673.7 GBG85627.1 - 0.0095 15.9 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_10 PF13374.6 GBG85627.1 - 0.01 15.7 14.0 2.7 8.0 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 GBG85627.1 - 0.068 13.5 9.8 0.13 12.5 9.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TPR_11 PF13414.6 GBG85627.1 - 0.099 12.3 0.3 0.57 9.9 0.0 2.5 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 GBG85627.1 - 1.4 9.7 9.2 23 5.9 0.1 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG85627.1 - 1.8 9.6 26.6 3.8 8.6 0.2 7.9 7 1 2 9 9 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG85627.1 - 4.5 8.0 10.6 2 9.1 0.0 4.5 4 1 2 6 6 6 0 Tetratricopeptide repeat zf-Mss51 PF13824.6 GBG85627.1 - 4.8 7.4 6.5 15 5.8 6.5 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SHMT PF00464.19 GBG85628.1 - 1.5e-16 60.0 0.0 2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase POB3_N PF17292.2 GBG85628.1 - 0.1 13.1 0.1 0.37 11.3 0.0 1.8 1 1 1 2 2 2 0 POB3-like N-terminal PH domain Aminotran_1_2 PF00155.21 GBG85630.1 - 8.7e-37 127.1 0.0 5.3e-13 48.9 0.0 3.3 2 1 1 3 3 3 3 Aminotransferase class I and II RVT_1 PF00078.27 GBG85630.1 - 4e-24 85.4 0.0 9.6e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85630.1 - 2.1e-14 53.4 0.0 6.1e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85630.1 - 3.4e-14 53.0 0.0 8.8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG85630.1 - 0.015 14.4 0.2 0.039 13.1 0.0 1.7 2 0 0 2 2 2 0 Autophagy protein Apg17 SOG2 PF10428.9 GBG85630.1 - 0.24 10.6 5.9 0.02 14.1 0.8 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein Ribosomal_L23eN PF03939.13 GBG85631.1 - 2.3e-14 53.3 14.2 5e-14 52.2 14.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 GBG85631.1 - 9.4e-14 51.6 1.5 9.4e-14 51.6 1.5 2.8 2 1 0 2 2 2 1 Ribosomal protein L23 Cauli_DNA-bind PF03310.13 GBG85631.1 - 0.043 13.9 1.1 4.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Phg_2220_C PF09524.10 GBG85631.1 - 0.23 11.6 1.9 1.3 9.2 0.4 2.3 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Filaggrin PF03516.13 GBG85632.1 - 3.2 8.6 9.1 2.2 9.1 5.8 2.3 2 0 0 2 2 2 0 Filaggrin Adap_comp_sub PF00928.21 GBG85633.1 - 1.7e-71 240.7 0.0 2.4e-65 220.6 0.0 2.1 1 1 1 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GBG85633.1 - 6.3e-08 32.7 0.1 1e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF659 PF04937.15 GBG85634.1 - 6.5e-32 110.5 0.0 9.6e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cwf_Cwc_15 PF04889.12 GBG85634.1 - 0.00047 20.0 19.5 0.00047 20.0 19.5 2.4 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein Plasmodium_Vir PF05795.11 GBG85634.1 - 0.2 11.0 3.0 0.28 10.5 2.1 1.6 1 1 1 2 2 2 0 Plasmodium vivax Vir protein CDC27 PF09507.10 GBG85634.1 - 1.4 8.2 19.6 2.4 7.4 19.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4642 PF15484.6 GBG85634.1 - 1.5 9.0 9.6 4.1 7.6 9.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) RNA_polI_A34 PF08208.11 GBG85634.1 - 8.5 6.4 12.7 18 5.3 12.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RVT_1 PF00078.27 GBG85637.1 - 6.6e-17 61.8 0.1 1.3e-16 60.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG85637.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85637.1 - 0.00018 22.0 0.0 0.00034 21.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG85637.1 - 0.00056 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG85637.1 - 0.007 17.0 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_S28 PF05577.12 GBG85638.1 - 1.7e-51 175.4 1.4 1.3e-36 126.4 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 SOBP PF15279.6 GBG85638.1 - 0.014 16.1 10.2 0.014 16.1 10.2 1.9 2 0 0 2 2 2 0 Sine oculis-binding protein CMS1 PF14617.6 GBG85638.1 - 1.6 8.0 3.0 2.3 7.5 3.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit FAE1_CUT1_RppA PF08392.12 GBG85642.1 - 2.4e-143 476.7 0.0 3e-143 476.4 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 GBG85642.1 - 6.7e-12 45.4 0.0 6.2e-11 42.3 0.0 2.5 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 GBG85642.1 - 6.3e-09 36.0 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.10 GBG85642.1 - 0.027 14.3 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 GBG85642.1 - 0.052 13.0 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Prominin PF05478.11 GBG85644.1 - 0.014 13.4 3.8 0.025 12.6 3.8 1.3 1 0 0 1 1 1 0 Prominin Bacillus_HBL PF05791.11 GBG85644.1 - 0.11 12.3 3.3 0.22 11.3 3.3 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Sulfatase_C PF14707.6 GBG85644.1 - 2.2 9.0 4.6 0.9 10.3 0.5 2.2 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF1664 PF07889.12 GBG85644.1 - 7.9 6.5 10.2 0.6 10.2 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2201_N PF13203.6 GBG85645.1 - 0.039 13.5 1.2 0.042 13.4 1.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain PTPRCAP PF15713.5 GBG85645.1 - 0.11 12.7 15.3 0.16 12.3 15.3 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG85645.1 - 1 7.6 17.4 1.2 7.4 17.4 1.0 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 GBG85645.1 - 2.5 7.7 23.0 3 7.5 23.0 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SspB PF04386.13 GBG85645.1 - 5.8 6.8 6.9 9.8 6.0 6.9 1.3 1 0 0 1 1 1 0 Stringent starvation protein B Nop53 PF07767.11 GBG85645.1 - 6.3 6.1 18.4 7.6 5.8 18.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GBG85645.1 - 8.9 4.4 18.9 10 4.2 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family DIRP PF06584.13 GBG85646.1 - 0.096 12.9 5.3 0.2 11.9 5.3 1.5 1 0 0 1 1 1 0 DIRP WDCP PF15390.6 GBG85646.1 - 0.42 8.9 1.9 1.1 7.5 0.0 2.0 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF3464 PF11947.8 GBG85646.1 - 4.2 7.1 5.4 8.7 6.1 5.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Radial_spoke_3 PF06098.11 GBG85646.1 - 8.7 5.5 17.2 13 4.9 17.2 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 eIF3_subunit PF08597.10 GBG85646.1 - 9.2 6.1 14.0 20 5.0 14.0 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Myb_DNA-bind_4 PF13837.6 GBG85647.1 - 3.1e-08 33.9 2.6 5.7e-08 33.0 1.4 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85647.1 - 0.0014 18.9 0.5 0.0032 17.7 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG85647.1 - 0.0066 16.7 0.7 0.031 14.5 1.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG85647.1 - 1.3 9.1 8.2 0.18 11.9 3.4 2.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG85648.1 - 9.5e-06 25.9 0.7 2.5e-05 24.6 0.7 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain C2 PF00168.30 GBG85649.1 - 1.3e-17 64.0 0.1 2.2e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 GBG85649.1 - 2.2e-10 40.3 0.0 3.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MFS_1 PF07690.16 GBG85649.1 - 0.0016 17.5 1.0 0.0022 17.0 1.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Alb1 PF09135.11 GBG85650.1 - 1.3e-05 26.0 12.1 1.9e-05 25.5 12.1 1.2 1 0 0 1 1 1 1 Alb1 DUF1003 PF06210.11 GBG85650.1 - 0.38 10.9 2.4 1.3 9.1 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) RT_RNaseH_2 PF17919.1 GBG85651.1 - 4.5e-29 100.4 0.0 7.7e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85651.1 - 8.1e-27 93.6 0.0 1.3e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85651.1 - 2.9e-24 85.8 0.0 4.2e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4746 PF15928.5 GBG85651.1 - 0.3 10.5 14.5 0.48 9.8 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIF_alpha PF05793.12 GBG85651.1 - 0.49 8.9 13.0 0.69 8.4 13.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 GBG85651.1 - 0.9 8.9 13.7 1.3 8.4 13.7 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 GBG85651.1 - 1.6 9.1 4.4 0.82 10.1 1.9 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 BUD22 PF09073.10 GBG85651.1 - 4.3 6.6 17.9 6.1 6.1 17.9 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG85651.1 - 4.9 5.3 12.5 7 4.8 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Afi1 PF07792.12 GBG85651.1 - 7.2 7.1 8.7 14 6.1 8.7 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop14 PF04147.12 GBG85651.1 - 7.7 4.6 18.3 12 4.0 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG85651.1 - 8 5.9 9.7 12 5.4 9.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist peroxidase PF00141.23 GBG85652.1 - 7.4e-47 159.9 0.0 1e-46 159.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DNA_pol_phi PF04931.13 GBG85652.1 - 0.0054 14.9 24.6 0.0073 14.5 24.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi TFB6 PF17110.5 GBG85652.1 - 0.016 15.0 4.4 0.024 14.4 4.4 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Mpp10 PF04006.12 GBG85652.1 - 0.075 11.5 8.7 0.097 11.1 8.7 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 GBG85652.1 - 0.089 12.1 9.2 0.14 11.5 9.2 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG85652.1 - 0.18 10.0 15.3 0.24 9.6 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 GBG85652.1 - 0.23 11.5 11.6 0.41 10.7 11.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FRQ PF09421.10 GBG85652.1 - 0.26 9.3 8.7 0.34 8.9 8.7 1.1 1 0 0 1 1 1 0 Frequency clock protein TRAP_alpha PF03896.16 GBG85652.1 - 0.65 9.2 4.7 1.2 8.3 4.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 GBG85652.1 - 1.2 8.5 15.3 1.8 7.9 15.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG85652.1 - 1.2 7.3 12.7 1.7 6.8 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CAF1A PF12253.8 GBG85652.1 - 1.8 8.8 23.5 3.4 7.9 23.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Sigma70_ner PF04546.13 GBG85652.1 - 2 8.2 17.5 3.5 7.5 17.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.14 GBG85652.1 - 4.4 7.1 9.0 7.8 6.2 9.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 GBG85652.1 - 4.5 8.0 23.6 9.5 7.0 23.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Cwf_Cwc_15 PF04889.12 GBG85652.1 - 6.8 6.4 29.6 11 5.6 29.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF659 PF04937.15 GBG85654.1 - 0.00093 19.1 1.7 0.001 19.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) PRNT PF15174.6 GBG85655.1 - 0.13 12.3 0.1 0.56 10.3 0.1 2.1 1 0 0 1 1 1 0 Prion-related protein testis-specific RT_RNaseH PF17917.1 GBG85657.1 - 4.8e-18 65.4 0.0 1.4e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85657.1 - 1.9e-15 56.7 0.0 4.9e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85657.1 - 4.3e-12 46.3 0.0 1.4e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG85657.1 - 6e-11 42.3 0.3 1.8e-10 40.8 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Rota_NS53 PF00981.17 GBG85657.1 - 0.07 12.0 0.8 0.11 11.3 0.8 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) DUF1664 PF07889.12 GBG85657.1 - 0.081 13.0 2.8 0.34 10.9 2.8 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF659 PF04937.15 GBG85659.1 - 3.3e-20 72.5 0.2 5.3e-20 71.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG85659.1 - 0.00057 19.6 0.1 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ASH PF15780.5 GBG85662.1 - 2.7e-24 85.2 0.0 5.3e-06 26.6 0.0 7.6 8 0 0 8 8 8 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 GBG85662.1 - 2.3e-14 53.4 3.8 0.0015 18.6 0.2 7.8 8 0 0 8 8 8 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 GBG85662.1 - 1.7e-10 41.0 3.0 0.1 12.9 0.1 7.8 9 0 0 9 9 9 3 Transmembrane protein 131-like Motile_Sperm PF00635.26 GBG85662.1 - 3.1e-07 30.2 0.0 0.022 14.6 0.0 6.2 7 0 0 7 7 7 1 MSP (Major sperm protein) domain MYCBPAP PF14646.6 GBG85662.1 - 0.0017 17.4 0.0 3.6 6.4 0.0 4.5 5 0 0 5 5 5 2 MYCBP-associated protein family RT_RNaseH_2 PF17919.1 GBG85663.1 - 3.7e-27 94.3 0.0 1.8e-12 47.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85663.1 - 4.9e-27 94.3 0.0 1e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85663.1 - 4.6e-18 65.5 0.2 1.4e-11 44.3 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG85663.1 - 1.1e-15 57.4 0.1 4e-15 55.7 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85663.1 - 8.1e-12 45.4 0.2 8.2e-11 42.1 0.0 2.8 2 1 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG85663.1 - 3.1e-11 43.0 0.0 7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG85663.1 - 0.00015 21.9 0.2 0.00079 19.6 0.1 2.2 2 0 0 2 2 2 1 H2C2 zinc finger eIF-1a PF01176.19 GBG85664.1 - 8.4e-23 80.0 0.2 1.3e-22 79.4 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RVT_1 PF00078.27 GBG85665.1 - 6.8e-11 42.1 0.0 9.5e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG85666.1 - 2e-08 34.7 0.6 9e-08 32.6 0.0 2.3 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85666.1 - 8.8e-06 26.3 0.2 3.7e-05 24.3 0.0 2.2 2 1 1 3 3 3 1 Aspartyl protease Asp_protease PF09668.10 GBG85666.1 - 0.0007 19.4 1.1 0.0013 18.5 1.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85666.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2E PF12382.8 GBG85666.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon peptidase HBS1_N PF08938.10 GBG85666.1 - 0.72 10.2 4.7 2.6 8.4 4.7 2.0 1 0 0 1 1 1 0 HBS1 N-terminus eIF_4EBP PF05456.11 GBG85667.1 - 2.1 8.3 4.5 1.1 9.2 0.7 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Presenilin PF01080.17 GBG85667.1 - 4.7 5.9 5.0 6.9 5.3 5.0 1.3 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG85669.1 - 2.3e-29 102.5 0.0 4.7e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tropomyosin PF00261.20 GBG85669.1 - 4.9e-05 22.8 53.6 4.9e-05 22.8 53.6 4.4 2 1 1 4 4 4 1 Tropomyosin Toxin-deaminase PF14424.6 GBG85669.1 - 0.12 12.5 1.5 0.5 10.5 1.5 2.1 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases SNARE PF05739.19 GBG85669.1 - 0.22 11.6 2.1 38 4.4 0.2 4.4 4 0 0 4 4 4 0 SNARE domain Tropomyosin PF00261.20 GBG85671.1 - 0.0014 18.1 48.3 0.0014 18.1 48.3 4.6 1 1 1 3 3 3 2 Tropomyosin NPV_P10 PF05531.12 GBG85671.1 - 1.1 9.8 17.6 15 6.2 0.6 6.1 7 0 0 7 7 7 0 Nucleopolyhedrovirus P10 protein bMG3 PF11974.8 GBG85671.1 - 1.7 8.7 9.1 0.55 10.3 1.4 3.3 3 0 0 3 3 3 0 Bacterial alpha-2-macroglobulin MG3 domain WEMBL PF05701.11 GBG85671.1 - 5.1 5.7 125.7 0.14 10.9 31.0 5.2 1 1 4 5 5 5 0 Weak chloroplast movement under blue light DUF948 PF06103.11 GBG85671.1 - 5.8 7.3 29.1 6.3 7.1 0.9 6.5 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) WEMBL PF05701.11 GBG85672.1 - 0.0059 15.4 3.7 0.0059 15.4 3.7 4.9 1 1 2 3 3 3 2 Weak chloroplast movement under blue light FAM110_N PF14161.6 GBG85672.1 - 0.041 14.1 0.4 0.16 12.2 0.4 2.0 1 0 0 1 1 1 0 Centrosome-associated N terminus MCM PF00493.23 GBG85673.1 - 1.7e-94 315.1 0.1 3e-94 314.3 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GBG85673.1 - 1e-31 109.4 0.0 2.1e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GBG85673.1 - 1.3e-27 96.0 2.1 4.6e-26 91.1 0.7 2.8 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 GBG85673.1 - 1.8e-12 47.7 0.0 7.7e-12 45.7 0.0 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GBG85673.1 - 1.2e-07 31.3 0.1 2.8e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GBG85673.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GBG85673.1 - 0.017 14.8 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-CCHC PF00098.23 GBG85676.1 - 0.22 11.7 1.9 0.42 10.8 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF287 PF03384.14 GBG85678.1 - 0.0048 17.3 1.5 0.0048 17.3 1.5 2.7 3 0 0 3 3 3 1 Drosophila protein of unknown function, DUF287 Sel1 PF08238.12 GBG85679.1 - 5.6e-147 474.8 99.7 7.5e-12 45.5 0.2 16.7 17 0 0 17 17 17 16 Sel1 repeat TPR_6 PF13174.6 GBG85679.1 - 0.017 15.7 31.8 10 7.0 0.0 11.0 14 2 0 14 14 14 0 Tetratricopeptide repeat NEMP PF10225.9 GBG85679.1 - 0.017 14.8 0.4 19 4.9 0.0 4.7 5 1 1 6 6 6 0 NEMP family DUF2530 PF10745.9 GBG85679.1 - 2 8.7 11.7 70 3.8 0.2 6.4 8 0 0 8 8 8 0 Protein of unknown function (DUF2530) RVT_1 PF00078.27 GBG85683.1 - 4e-07 29.8 0.1 8e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG85683.1 - 0.00046 20.4 5.1 0.06 13.6 0.0 3.8 3 0 0 3 3 3 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG85683.1 - 0.0069 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease ERM PF00769.19 GBG85683.1 - 4 7.2 22.7 11 5.7 22.7 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CLZ PF16526.5 GBG85683.1 - 6.7 7.1 9.1 0.17 12.3 1.3 2.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PMSR PF01625.21 GBG85685.1 - 4.9e-46 156.7 0.1 6.7e-46 156.2 0.1 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase LEA_2 PF03168.13 GBG85686.1 - 0.00015 22.3 0.0 0.00026 21.5 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein RT_RNaseH_2 PF17919.1 GBG85687.1 - 1.7e-26 92.1 0.0 5.4e-26 90.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85687.1 - 8.9e-23 81.0 0.0 1.9e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85687.1 - 2.2e-21 76.1 0.0 6.1e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85687.1 - 4e-17 62.1 2.2 3.4e-16 59.1 1.0 2.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG85687.1 - 2.3e-10 40.7 0.0 8.7e-10 38.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG85687.1 - 0.00012 22.6 0.0 0.0003 21.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85687.1 - 0.00068 19.4 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG85687.1 - 0.00069 20.1 0.0 0.0017 18.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG85687.1 - 0.00078 19.7 0.2 0.046 14.0 0.0 3.7 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG85687.1 - 0.0022 17.8 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG85687.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Laminin_II PF06009.12 GBG85687.1 - 1.3 9.1 6.7 5.4 7.0 1.3 2.9 2 0 0 2 2 2 0 Laminin Domain II CLZ PF16526.5 GBG85687.1 - 1.8 9.0 8.6 4.6 7.7 1.3 4.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PIEZO PF15917.5 GBG85687.1 - 4.9 6.6 9.6 4.5 6.7 7.8 1.9 1 1 0 1 1 1 0 Piezo BUD22 PF09073.10 GBG85688.1 - 0.096 12.0 35.5 0.16 11.3 35.5 1.3 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GBG85688.1 - 0.4 9.4 10.4 0.49 9.1 10.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 GBG85688.1 - 0.42 10.0 41.2 0.61 9.5 41.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG85688.1 - 1.7 6.7 40.8 2.4 6.2 40.8 1.1 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 GBG85688.1 - 6.5 5.7 17.9 8.7 5.3 17.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Lin-8 PF03353.15 GBG85688.1 - 7.5 6.0 20.6 15 5.1 20.6 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 GBG85688.1 - 9.5 4.9 19.8 14 4.3 19.8 1.2 1 0 0 1 1 1 0 Presenilin RT_RNaseH PF17917.1 GBG85689.1 - 7.1e-20 71.3 0.0 1.6e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85689.1 - 6.8e-19 67.8 0.0 1.4e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG85689.1 - 4e-07 30.5 0.0 1.1e-06 29.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG85689.1 - 6.8e-05 22.5 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG85689.1 - 0.00018 22.1 0.0 0.00042 20.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85689.1 - 0.0033 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85689.1 - 0.05 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG85689.1 - 0.16 12.2 0.7 0.67 10.3 0.7 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG85690.1 - 4.7e-20 71.8 0.0 9.4e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85690.1 - 4.3e-19 68.4 0.0 8.3e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG85690.1 - 2.2e-07 31.3 0.0 6.3e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG85690.1 - 3.8e-05 23.3 0.0 7.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG85690.1 - 0.0001 22.9 0.0 0.00025 21.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85690.1 - 0.0019 18.0 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85690.1 - 0.029 14.7 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease ICA69 PF04629.14 GBG85690.1 - 0.42 10.9 4.0 0.68 10.2 4.0 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain Myb_DNA-binding PF00249.31 GBG85691.1 - 4.3e-11 42.8 0.0 7.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-CCHC_6 PF15288.6 GBG85691.1 - 4.2 7.3 8.3 3 7.7 2.7 3.0 2 0 0 2 2 2 0 Zinc knuckle Myb_DNA-binding PF00249.31 GBG85692.1 - 4.3e-11 42.8 0.0 7.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-CCHC_6 PF15288.6 GBG85692.1 - 4.2 7.3 8.3 3 7.7 2.7 3.0 2 0 0 2 2 2 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG85694.1 - 0.00019 21.7 0.7 0.00031 21.1 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain OTU PF02338.19 GBG85695.1 - 0.0013 19.2 0.1 0.043 14.3 0.1 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease CBS PF00571.28 GBG85697.1 - 1.1e-26 93.0 5.2 6.7e-08 32.9 0.0 4.5 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 GBG85697.1 - 2.6e-12 46.5 0.0 5.6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 PB1 domain DUF512 PF04459.12 GBG85697.1 - 0.17 11.1 0.1 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF512) RVT_1 PF00078.27 GBG85698.1 - 3e-49 167.5 0.0 1.8e-26 93.1 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85698.1 - 7.3e-14 51.6 0.0 1.9e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG85698.1 - 3.4e-09 37.2 0.0 1.4e-07 32.0 0.0 2.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85698.1 - 2.6e-07 31.1 0.0 1e-06 29.2 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG85698.1 - 4.7e-05 23.6 1.0 0.83 10.0 0.0 3.7 3 0 0 3 3 3 2 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG85698.1 - 7.5e-05 23.0 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG85698.1 - 0.00012 21.9 0.0 0.00035 20.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85698.1 - 0.00016 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Sec34 PF04136.15 GBG85698.1 - 0.35 10.7 2.2 0.36 10.7 0.2 2.0 2 0 0 2 2 2 0 Sec34-like family DUF1664 PF07889.12 GBG85698.1 - 1.1 9.3 4.3 0.75 9.8 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_Gp23 PF10669.9 GBG85699.1 - 2.7 8.4 9.9 4.3 7.7 9.9 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CDC45 PF02724.14 GBG85699.1 - 4.2 5.5 6.0 4.8 5.3 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein LSM PF01423.22 GBG85700.1 - 2.1e-08 33.7 0.4 0.0038 16.9 0.0 2.5 2 0 0 2 2 2 2 LSM domain Acetyltransf_1 PF00583.25 GBG85700.1 - 3e-08 33.9 0.0 8.9e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GBG85700.1 - 8.3e-05 22.9 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GBG85700.1 - 0.0005 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG85700.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein LSM PF01423.22 GBG85701.1 - 1.9e-08 33.9 0.4 0.0036 17.0 0.0 2.5 2 0 0 2 2 2 2 LSM domain Acetyltransf_1 PF00583.25 GBG85701.1 - 2.8e-08 34.0 0.0 8.4e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GBG85701.1 - 7.8e-05 23.0 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GBG85701.1 - 0.00046 20.1 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG85701.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Phage_lysis PF03245.13 GBG85702.1 - 0.14 12.3 1.8 0.3 11.2 1.8 1.5 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein gag-asp_proteas PF13975.6 GBG85702.1 - 0.15 12.7 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85702.1 - 0.19 12.4 0.0 0.8 10.4 0.0 2.1 3 0 0 3 3 3 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG85703.1 - 1.7e-15 56.9 0.1 4.5e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85703.1 - 3.9e-11 42.9 0.0 7.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85703.1 - 4.7e-11 42.9 0.0 9.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85703.1 - 1.1e-08 35.0 0.1 2.2e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85703.1 - 1.9e-06 28.1 0.0 4.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85703.1 - 0.0035 17.5 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG85703.1 - 0.11 12.6 0.5 0.27 11.4 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.22 GBG85704.1 - 1.4e-16 60.0 0.0 5.1e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GBG85704.1 - 0.035 14.2 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.8 GBG85704.1 - 0.044 13.9 0.1 5.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 RRM_9 PF18444.1 GBG85704.1 - 0.15 11.9 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Maf PF02545.14 GBG85705.1 - 5.9e-46 156.3 0.0 9e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 Maf-like protein Whirly PF08536.11 GBG85705.1 - 3e-30 104.8 0.0 4.9e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Whirly transcription factor DUF952 PF06108.12 GBG85706.1 - 1.1e-21 76.7 0.0 1.4e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Rhodanese PF00581.20 GBG85707.1 - 2.7e-05 24.6 0.0 6.6e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain CAAD PF14159.6 GBG85707.1 - 0.0061 16.4 0.7 0.023 14.6 0.1 2.3 1 1 1 2 2 2 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF4101 PF13355.6 GBG85708.1 - 1.3e-31 109.4 0.1 3e-31 108.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4101) PAE PF03283.13 GBG85709.1 - 3.4e-35 121.8 0.0 2.3e-32 112.5 0.2 2.4 2 1 0 2 2 2 1 Pectinacetylesterase ABC_tran PF00005.27 GBG85709.1 - 1.1e-24 87.6 0.0 1.9e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GBG85709.1 - 1.2e-10 41.2 26.3 3.6e-10 39.6 26.3 1.9 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 GBG85709.1 - 1.6e-07 31.4 0.2 0.0076 16.1 0.2 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GBG85709.1 - 0.0003 20.7 0.1 0.0006 19.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 GBG85709.1 - 0.00037 20.2 0.3 0.0028 17.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 GBG85709.1 - 0.011 15.2 0.0 0.11 11.9 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GBG85709.1 - 0.015 15.7 1.1 0.027 14.9 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 GBG85709.1 - 0.025 15.1 0.0 0.025 15.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG85709.1 - 0.025 14.1 0.1 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GBG85709.1 - 0.028 14.7 0.7 0.073 13.3 0.0 2.1 3 0 0 3 3 2 0 AAA domain PDR_CDR PF06422.12 GBG85709.1 - 0.03 14.2 1.4 0.25 11.3 0.1 2.5 2 0 0 2 2 2 0 CDR ABC transporter DUF533 PF04391.12 GBG85709.1 - 0.057 13.0 0.3 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Peptidase_M20 PF01546.28 GBG85710.1 - 2.9e-30 105.5 0.1 5.1e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 GBG85710.1 - 4.2e-06 26.6 0.0 6.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 GBG85710.1 - 6e-05 22.9 0.1 0.00018 21.4 0.1 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Mg_trans_NIPA PF05653.14 GBG85711.1 - 1.3e-18 67.2 19.5 9.8e-18 64.3 19.5 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA Ribosomal_S27e PF01667.17 GBG85711.1 - 0.0027 17.3 0.1 0.0052 16.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 DUF2298 PF10060.9 GBG85711.1 - 0.004 15.9 10.3 0.0056 15.5 10.3 1.1 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) DUF2631 PF10939.8 GBG85711.1 - 1.4 8.8 3.2 2.7 7.9 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2631) RT_RNaseH_2 PF17919.1 GBG85712.1 - 1.9e-32 111.2 0.0 4.4e-32 110.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85712.1 - 2.3e-27 95.3 0.0 4.7e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85712.1 - 4.7e-23 81.9 0.0 8.6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG85712.1 - 1.2e-16 61.0 0.0 4.1e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG85712.1 - 3.2e-16 59.2 0.1 6.6e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG85712.1 - 0.0062 17.2 0.0 0.018 15.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85712.1 - 0.015 15.9 0.0 0.04 14.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1564 PF07600.11 GBG85712.1 - 0.16 11.7 0.0 0.47 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) rve PF00665.26 GBG85713.1 - 1.3e-10 41.5 0.0 2.8e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG85713.1 - 8.1e-10 38.7 0.2 1.8e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85713.1 - 3.6e-09 36.5 0.0 6.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Jnk-SapK_ap_N PF09744.9 GBG85713.1 - 0.0033 17.7 7.3 0.0033 17.7 7.3 4.9 5 0 0 5 5 5 1 JNK_SAPK-associated protein-1 zf-H2C2 PF09337.10 GBG85713.1 - 0.055 13.7 0.8 0.12 12.7 0.8 1.6 1 0 0 1 1 1 0 H2C2 zinc finger YqzH PF14164.6 GBG85713.1 - 0.19 11.8 0.2 0.55 10.3 0.2 1.7 1 0 0 1 1 1 0 YqzH-like protein zf-CCHC_4 PF14392.6 GBG85713.1 - 0.19 11.5 1.4 0.4 10.4 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle CENP-N PF05238.13 GBG85713.1 - 2.3 7.4 8.0 6.9 5.9 8.0 1.7 1 0 0 1 1 1 0 Kinetochore protein CHL4 like PP2C PF00481.21 GBG85714.1 - 5.1e-38 131.2 0.8 1.1e-32 113.7 0.1 2.8 3 0 0 3 3 3 2 Protein phosphatase 2C RVT_1 PF00078.27 GBG85714.1 - 5.5e-29 101.3 0.0 1e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85714.1 - 8.7e-23 80.2 0.0 2e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85714.1 - 4.4e-22 78.4 0.0 9.2e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FHA PF00498.26 GBG85714.1 - 2.5e-18 66.2 0.1 4.9e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 FHA domain Integrase_H2C2 PF17921.1 GBG85714.1 - 7.2e-17 61.3 1.7 2.3e-16 59.7 0.6 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain Yop-YscD_cpl PF16697.5 GBG85714.1 - 3.2e-09 37.0 0.1 8e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain rve PF00665.26 GBG85714.1 - 8.5e-08 32.4 0.0 2.9e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85714.1 - 0.00046 20.4 0.2 0.0011 19.1 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger SpoIIE PF07228.12 GBG85714.1 - 0.035 14.0 0.2 0.11 12.4 0.2 1.9 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) gag-asp_proteas PF13975.6 GBG85715.1 - 5.4e-08 33.3 0.0 1.8e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85715.1 - 4.1e-05 24.2 0.0 0.00013 22.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85715.1 - 0.00098 18.9 1.0 0.0018 18.1 1.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85715.1 - 0.043 14.1 0.0 0.17 12.2 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease RXLR PF16810.5 GBG85715.1 - 0.6 10.5 1.8 33 4.9 1.2 2.9 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity gag-asp_proteas PF13975.6 GBG85716.1 - 3.5e-08 33.9 0.0 1.1e-07 32.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85716.1 - 2.6e-05 24.8 0.1 8.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG85716.1 - 0.0006 19.6 1.0 0.0011 18.7 1.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85716.1 - 0.023 15.0 0.0 0.1 12.9 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease PTPRCAP PF15713.5 GBG85716.1 - 1.6 9.0 10.7 0.12 12.7 4.1 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RXLR PF16810.5 GBG85716.1 - 1.9 8.9 4.4 21 5.5 1.2 2.8 3 0 0 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity Oxysterol_BP PF01237.18 GBG85716.1 - 3.9 6.2 6.7 8 5.2 6.7 1.4 1 0 0 1 1 1 0 Oxysterol-binding protein CDC45 PF02724.14 GBG85717.1 - 0.032 12.5 12.4 0.032 12.6 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG85717.1 - 0.1 12.4 12.9 0.12 12.2 12.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4569 PF15133.6 GBG85717.1 - 0.13 12.0 3.2 0.15 11.8 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Vfa1 PF08432.10 GBG85717.1 - 0.18 12.1 10.3 0.22 11.9 10.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HSP70 PF00012.20 GBG85717.1 - 0.8 7.8 6.4 0.97 7.5 6.4 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF3381 PF11861.8 GBG85717.1 - 0.9 9.3 22.6 1.4 8.7 22.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Presenilin PF01080.17 GBG85717.1 - 1 8.1 6.5 1.1 7.9 6.5 1.1 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 GBG85717.1 - 3.1 7.5 6.4 3.3 7.4 6.4 1.1 1 0 0 1 1 1 0 AAA domain DNA_pol_phi PF04931.13 GBG85717.1 - 3.7 5.5 11.5 4.4 5.3 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Connexin PF00029.19 GBG85717.1 - 4.8 6.9 8.5 7.8 6.2 8.5 1.4 1 0 0 1 1 1 0 Connexin Hid1 PF12722.7 GBG85717.1 - 6.4 4.8 5.9 6.8 4.7 5.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Radial_spoke_3 PF06098.11 GBG85718.1 - 0.0058 15.9 12.4 0.0058 15.9 12.4 1.8 1 1 1 2 2 2 1 Radial spoke protein 3 DUF2927 PF11150.8 GBG85718.1 - 0.041 13.9 2.5 0.068 13.2 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) EMC3_TMCO1 PF01956.16 GBG85718.1 - 0.87 9.3 2.7 1.8 8.3 2.7 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RVT_1 PF00078.27 GBG85719.1 - 7.1e-36 123.8 0.1 1.1e-35 123.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG85719.1 - 8.8e-19 67.9 0.2 4.7e-09 36.3 0.1 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG85719.1 - 2.4e-11 43.6 0.0 1.1e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG85719.1 - 7.9e-06 26.4 0.0 1.9e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85719.1 - 9.8e-06 25.4 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG85719.1 - 3.9e-05 23.4 1.1 0.00012 21.8 1.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG85719.1 - 0.00077 20.0 0.0 0.0026 18.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG85719.1 - 0.0039 17.0 0.0 0.0093 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG85719.1 - 0.059 13.2 0.0 0.97 9.2 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease RT_RNaseH PF17917.1 GBG85719.1 - 0.092 13.0 0.0 0.41 11.0 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Chloroa_b-bind PF00504.21 GBG85720.1 - 9.6e-52 175.7 0.0 1.4e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF4101 PF13355.6 GBG85721.1 - 3.9e-33 114.4 0.2 8e-33 113.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4101) EF1G PF00647.19 GBG85723.1 - 2.1e-40 137.1 0.3 1.2e-39 134.6 0.1 2.3 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 GBG85723.1 - 4.6e-10 39.7 0.0 1.4e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GBG85723.1 - 4.8e-08 33.1 0.0 4.8e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GBG85723.1 - 1.6e-06 28.4 0.0 3.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GBG85723.1 - 1.5e-05 24.9 0.0 3.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GBG85723.1 - 0.0005 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GBG85723.1 - 0.0073 16.5 0.0 0.025 14.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.22 GBG85724.1 - 6.6e-70 230.9 0.2 1.7e-24 85.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GBG85724.1 - 2.9e-28 97.8 0.3 6.5e-28 96.7 0.3 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 GBG85724.1 - 3.7e-08 33.1 0.0 0.001 18.9 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GBG85724.1 - 5.6e-08 32.4 0.0 0.025 14.1 0.0 3.3 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GBG85724.1 - 1.8e-05 24.7 2.8 0.74 9.9 0.0 3.5 2 1 1 3 3 3 3 RNA binding motif Nup35_RRM_2 PF14605.6 GBG85724.1 - 0.00013 21.9 0.0 1.9 8.5 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GBG85724.1 - 0.00017 21.6 0.1 0.4 10.8 0.0 3.8 3 1 0 3 3 3 1 RNA recognition motif Limkain-b1 PF11608.8 GBG85724.1 - 0.0054 16.8 0.5 3.8 7.6 0.0 3.6 3 0 0 3 3 3 1 Limkain b1 SET_assoc PF11767.8 GBG85724.1 - 0.014 15.0 0.0 3.6 7.3 0.0 3.0 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 GBG85724.1 - 0.016 15.4 0.0 0.47 10.7 0.0 2.8 2 1 0 2 2 2 0 RRM-like domain GH97_C PF14509.6 GBG85724.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation OB_RNB PF08206.11 GBG85724.1 - 0.3 10.8 0.9 6.2 6.6 0.0 2.8 3 0 0 3 3 3 0 Ribonuclease B OB domain RRM_1 PF00076.22 GBG85725.1 - 7.1e-70 230.8 0.2 1.7e-24 85.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GBG85725.1 - 3e-28 97.8 0.3 6.6e-28 96.7 0.3 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 GBG85725.1 - 3.9e-08 33.0 0.0 0.001 18.9 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GBG85725.1 - 6e-08 32.3 0.0 0.026 14.1 0.0 3.3 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GBG85725.1 - 1.9e-05 24.6 2.7 0.76 9.8 0.0 3.5 2 1 1 3 3 3 3 RNA binding motif Nup35_RRM_2 PF14605.6 GBG85725.1 - 0.00014 21.8 0.0 2 8.5 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GBG85725.1 - 0.0002 21.4 0.1 0.41 10.8 0.0 3.7 3 1 0 3 3 3 1 RNA recognition motif Limkain-b1 PF11608.8 GBG85725.1 - 0.0056 16.7 0.5 3.9 7.6 0.0 3.6 3 0 0 3 3 3 1 Limkain b1 SET_assoc PF11767.8 GBG85725.1 - 0.016 14.9 0.0 3.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 GBG85725.1 - 0.018 15.3 0.0 0.48 10.7 0.0 2.8 2 1 0 2 2 2 0 RRM-like domain GH97_C PF14509.6 GBG85725.1 - 0.023 14.9 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation DUF3952 PF13130.6 GBG85726.1 - 0.046 13.9 0.1 0.046 13.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) RIBIOP_C PF04950.12 GBG85726.1 - 1.7 8.0 6.1 2.2 7.6 6.1 1.1 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Sec62 PF03839.16 GBG85726.1 - 2.1 7.8 6.7 2.7 7.5 6.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 5_nucleotid PF05761.14 GBG85726.1 - 2.2 7.1 5.6 2.6 6.8 5.6 1.1 1 0 0 1 1 1 0 5' nucleotidase family APH PF01636.23 GBG85727.1 - 4.8e-08 33.2 0.0 4.4e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GBG85727.1 - 8.1e-07 28.7 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GBG85727.1 - 1.1e-06 28.2 0.1 4.6e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GBG85727.1 - 6e-06 26.0 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 GBG85727.1 - 0.00034 20.0 0.0 0.0005 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WaaY PF06176.11 GBG85727.1 - 0.0022 17.6 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.20 GBG85727.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Ribosomal_60s PF00428.19 GBG85727.1 - 0.014 16.0 0.9 0.014 16.0 0.9 3.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein Choline_kinase PF01633.20 GBG85727.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PI3_PI4_kinase PF00454.27 GBG85727.1 - 0.2 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase ACTH_assoc PF16102.5 GBG85729.1 - 0.95 10.4 2.6 1.8 9.5 0.6 2.5 2 0 0 2 2 2 0 ACTH-associated domain DUF3439 PF11921.8 GBG85730.1 - 0.0014 18.6 12.5 0.0024 17.8 12.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Reprolysin_2 PF13574.6 GBG85730.1 - 0.12 12.2 0.5 0.17 11.7 0.5 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Exonuc_VII_S PF02609.16 GBG85730.1 - 0.14 12.3 1.2 8.3 6.6 1.2 2.3 1 1 0 1 1 1 0 Exonuclease VII small subunit DDE_Tnp_4 PF13359.6 GBG85731.1 - 9.6e-30 103.3 0.0 1.9e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85731.1 - 3.9e-16 59.3 0.0 6.3e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85731.1 - 0.0003 20.5 0.0 0.49 10.0 0.1 2.3 2 0 0 2 2 2 2 Transposase DDE domain RT_RNaseH PF17917.1 GBG85732.1 - 2.9e-21 75.7 0.0 6.1e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85732.1 - 6.7e-14 51.7 0.8 2.4e-13 49.9 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG85732.1 - 6.9e-13 48.8 0.0 3.4e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG85732.1 - 9.9e-12 44.8 0.0 2.1e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG85732.1 - 2.1e-05 24.7 0.0 4.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG85733.1 - 4.1e-29 100.6 0.0 5.1e-15 55.3 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85733.1 - 1.7e-27 95.7 0.0 4e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85733.1 - 1.4e-26 93.4 0.0 2.4e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG85733.1 - 4.6e-14 52.3 1.0 2.3e-13 50.0 0.0 2.7 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG85733.1 - 3.3e-11 43.4 0.0 1.5e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG85733.1 - 3.9e-05 23.8 0.0 0.00011 22.3 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG85733.1 - 0.19 11.5 0.1 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like RT_RNaseH_2 PF17919.1 GBG85734.1 - 6.9e-25 87.0 0.0 1.7e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85734.1 - 1.5e-24 86.3 0.0 3.4e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85734.1 - 2.2e-19 69.3 0.4 6.5e-19 67.8 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85734.1 - 3.1e-11 43.2 0.1 4.8e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG85734.1 - 1.4e-09 38.2 0.0 4.6e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG85734.1 - 9.3e-09 35.8 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85734.1 - 7e-07 29.7 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG85734.1 - 6.2e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85734.1 - 0.00048 19.9 0.0 0.00085 19.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG85734.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF1223 PF06764.11 GBG85735.1 - 0.36 10.8 8.4 0.2 11.6 6.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1223) Ribosomal_L34e PF01199.18 GBG85735.1 - 0.62 10.4 6.2 0.61 10.4 1.2 2.3 2 0 0 2 2 2 0 Ribosomal protein L34e zf-CCHC PF00098.23 GBG85736.1 - 2.7e-06 27.2 4.3 2.7e-06 27.2 4.3 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG85736.1 - 0.032 14.1 0.8 0.093 12.6 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle Annexin PF00191.20 GBG85737.1 - 4e-43 145.3 0.4 1.1e-16 60.7 0.1 3.9 4 0 0 4 4 4 3 Annexin DDE_Tnp_4 PF13359.6 GBG85738.1 - 7.3e-16 58.2 0.0 1.3e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85738.1 - 1.5e-06 28.0 0.0 4.1e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG85740.1 - 0.0078 16.6 2.5 0.058 13.8 0.0 2.9 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain GTP_EFTU PF00009.27 GBG85742.1 - 1.2e-68 230.5 0.0 1.8e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GBG85742.1 - 6.7e-46 155.0 0.1 1.3e-45 154.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 GBG85742.1 - 1.1e-32 111.9 0.3 2.5e-32 110.8 0.1 1.7 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 GBG85742.1 - 3.4e-25 87.9 0.0 1e-24 86.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GBG85742.1 - 2.4e-14 53.5 0.1 6.6e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GBG85742.1 - 7.6e-07 29.0 0.1 1.7e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GBG85742.1 - 0.00062 19.8 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GBG85742.1 - 0.0082 15.5 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family ABC2_membrane PF01061.24 GBG85744.1 - 2.4e-42 144.7 22.0 2.4e-42 144.7 22.0 1.6 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 GBG85744.1 - 2.6e-29 102.5 0.0 4.8e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG85744.1 - 4.1e-08 32.7 23.7 7.3e-08 31.9 23.7 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG85744.1 - 6.2e-08 32.8 0.3 0.0029 17.4 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GBG85744.1 - 6e-06 26.7 0.1 1.2e-05 25.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GBG85744.1 - 7.3e-06 25.6 0.1 1.6e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GBG85744.1 - 0.00013 22.0 0.1 0.00028 20.8 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 GBG85744.1 - 0.00083 19.9 0.1 0.0022 18.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GBG85744.1 - 0.00095 19.5 0.2 0.011 16.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GBG85744.1 - 0.0056 16.4 0.1 0.0091 15.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 GBG85744.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 GBG85744.1 - 0.011 15.8 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 GBG85744.1 - 0.011 15.1 0.1 0.097 12.1 0.1 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 GBG85744.1 - 0.021 14.4 0.1 0.041 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 GBG85744.1 - 0.024 13.6 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 GBG85744.1 - 0.065 13.5 0.3 0.26 11.5 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GBG85744.1 - 0.078 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 GBG85744.1 - 0.086 12.6 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 GBG85744.1 - 0.12 12.3 0.1 0.98 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 GBG85744.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Dynamin family ABC_ATPase PF09818.9 GBG85744.1 - 0.13 11.0 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class T2SSE PF00437.20 GBG85744.1 - 0.13 11.3 0.2 0.22 10.6 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PHO4 PF01384.20 GBG85744.1 - 0.24 10.4 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 Phosphate transporter family RVT_1 PF00078.27 GBG85745.1 - 1.9e-05 24.3 0.1 0.18 11.3 0.0 3.1 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG85745.1 - 0.00052 20.0 4.6 0.00099 19.1 3.4 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG85745.1 - 0.17 11.7 7.5 0.12 12.3 5.1 2.0 2 0 0 2 2 2 0 Zinc knuckle Phlebovirus_NSM PF07246.11 GBG85745.1 - 4.3 6.6 8.5 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M RNA_polI_A34 PF08208.11 GBG85746.1 - 0.02 15.0 46.4 0.025 14.7 46.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SAPS PF04499.15 GBG85746.1 - 0.17 10.6 6.4 0.16 10.7 6.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CENP-N PF05238.13 GBG85746.1 - 0.21 10.9 10.6 0.18 11.0 10.6 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DDHD PF02862.17 GBG85746.1 - 0.23 11.6 6.6 0.23 11.6 6.6 1.1 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 GBG85746.1 - 0.73 8.5 22.8 0.92 8.2 22.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 GBG85746.1 - 0.76 9.8 6.8 0.71 9.9 6.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 GBG85746.1 - 1.2 9.1 6.7 1.3 9.0 6.7 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF5308 PF17233.2 GBG85746.1 - 2 8.6 5.0 2.1 8.5 5.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SLC12 PF03522.15 GBG85746.1 - 2.1 7.3 15.0 2.4 7.1 15.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 AAA_11 PF13086.6 GBG85746.1 - 2.6 7.8 15.6 2.9 7.6 15.6 1.1 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpc4 PF05132.14 GBG85746.1 - 2.7 8.4 23.0 3.7 8.0 23.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3807 PF12720.7 GBG85746.1 - 2.7 8.2 25.8 4.2 7.6 25.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 GBG85746.1 - 4.6 5.9 16.2 5.1 5.7 16.2 1.0 1 0 0 1 1 1 0 Presenilin Gti1_Pac2 PF09729.9 GBG85746.1 - 6 6.9 19.1 9 6.3 19.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family eIF3_subunit PF08597.10 GBG85746.1 - 7.2 6.4 38.8 10 5.9 38.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SRP-alpha_N PF04086.13 GBG85746.1 - 7.4 6.4 31.6 8.2 6.3 31.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RT_RNaseH_2 PF17919.1 GBG85747.1 - 4.9e-17 61.8 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85747.1 - 1.7e-09 37.9 0.1 4.2e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG85747.1 - 1.6e-08 34.2 1.2 2.9e-08 33.4 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG85747.1 - 3.8e-07 30.3 0.3 8.2e-07 29.2 0.3 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG85747.1 - 0.018 14.9 2.7 0.031 14.1 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle ABC_tran PF00005.27 GBG85748.1 - 4.3e-29 101.8 0.0 6.4e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG85748.1 - 1e-08 35.4 0.3 0.0019 18.1 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GBG85748.1 - 4.4e-06 26.3 0.1 9.5e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG85748.1 - 6.7e-05 23.3 0.1 0.00015 22.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC2_membrane PF01061.24 GBG85748.1 - 8.5e-05 22.1 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 GBG85748.1 - 0.00015 21.7 0.1 0.00029 20.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 GBG85748.1 - 0.00066 20.2 0.1 0.0011 19.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 GBG85748.1 - 0.00089 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 GBG85748.1 - 0.0022 17.5 0.0 0.027 13.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GBG85748.1 - 0.0027 18.0 0.2 0.011 16.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GBG85748.1 - 0.0039 17.3 0.1 0.0074 16.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 GBG85748.1 - 0.0072 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 GBG85748.1 - 0.0075 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GBG85748.1 - 0.013 15.1 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 GBG85748.1 - 0.017 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_33 PF13671.6 GBG85748.1 - 0.034 14.3 0.1 0.068 13.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain ABC_ATPase PF09818.9 GBG85748.1 - 0.042 12.7 0.1 0.069 11.9 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Dynamin_N PF00350.23 GBG85748.1 - 0.048 13.7 0.1 0.088 12.9 0.1 1.4 1 0 0 1 1 1 0 Dynamin family NTPase_1 PF03266.15 GBG85748.1 - 0.059 13.3 0.4 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 GBG85748.1 - 0.066 13.4 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GBG85748.1 - 0.076 13.4 0.1 0.37 11.2 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 GBG85748.1 - 0.079 11.9 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 GBG85748.1 - 0.1 13.2 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GBG85748.1 - 0.14 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 GBG85748.1 - 0.16 11.9 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 GBG85748.1 - 0.17 11.3 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein RVT_1 PF00078.27 GBG85749.1 - 1e-17 64.4 0.0 2.6e-17 63.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG85749.1 - 0.00038 21.1 3.3 0.00038 21.1 3.3 3.1 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase DUF659 PF04937.15 GBG85750.1 - 3.4e-13 49.7 0.0 5.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) FYVE PF01363.21 GBG85750.1 - 0.022 14.9 0.3 0.043 14.0 0.3 1.4 1 0 0 1 1 1 0 FYVE zinc finger Aida_N PF08910.10 GBG85751.1 - 0.013 15.8 0.9 0.036 14.5 0.6 1.9 1 1 0 1 1 1 0 Aida N-terminus FlaC_arch PF05377.11 GBG85751.1 - 0.057 13.8 0.8 0.057 13.8 0.8 3.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 GBG85751.1 - 0.2 12.0 5.2 0.28 11.5 2.0 2.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lzipper-MIP1 PF14389.6 GBG85751.1 - 0.22 11.9 9.8 6.7 7.1 0.0 3.8 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Shugoshin_N PF07558.11 GBG85751.1 - 0.67 9.9 6.1 1.1 9.2 0.0 3.4 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Macoilin PF09726.9 GBG85751.1 - 0.71 8.4 9.8 0.95 7.9 9.8 1.1 1 0 0 1 1 1 0 Macoilin family LPP PF04728.13 GBG85751.1 - 1.1 9.7 5.5 7.3 7.1 0.1 3.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 GBG85751.1 - 1.6 8.9 10.8 3.1 8.0 4.1 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 GBG85751.1 - 1.6 9.1 16.1 3.2 8.2 0.2 4.2 2 1 3 5 5 5 0 Csm1 N-terminal domain COG5 PF10392.9 GBG85751.1 - 1.8 8.7 6.3 1.2 9.3 1.3 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Spc7 PF08317.11 GBG85751.1 - 1.8 7.4 17.7 1 8.2 10.0 2.2 2 1 1 3 3 3 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 GBG85751.1 - 3.1 7.9 7.9 0.94 9.6 0.5 3.2 3 0 0 3 3 3 0 TolA binding protein trimerisation ABC2_membrane PF01061.24 GBG85752.1 - 9.5e-42 142.8 27.4 1.4e-41 142.3 27.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GBG85752.1 - 2.9e-27 95.9 0.0 4.2e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG85752.1 - 7.8e-08 31.8 22.1 7.8e-08 31.8 22.1 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG85752.1 - 1e-06 28.8 0.4 0.02 14.7 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GBG85752.1 - 1.5e-05 24.6 0.1 3.4e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG85752.1 - 5.9e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GBG85752.1 - 0.0003 20.7 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 GBG85752.1 - 0.0037 17.8 0.2 0.0079 16.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 GBG85752.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MeaB PF03308.16 GBG85752.1 - 0.015 14.3 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 GBG85752.1 - 0.019 15.2 0.0 0.094 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GBG85752.1 - 0.042 13.9 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 GBG85752.1 - 0.046 13.3 0.1 0.094 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 GBG85752.1 - 0.048 13.1 0.0 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Cytidylate_kin PF02224.18 GBG85752.1 - 0.055 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase ABC_ATPase PF09818.9 GBG85752.1 - 0.095 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 GBG85752.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GBG85752.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 GBG85752.1 - 0.17 12.4 0.0 0.29 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 GBG85753.1 - 5.5e-06 26.0 0.0 0.014 14.9 0.0 2.3 1 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG85753.1 - 0.00019 21.4 0.4 0.00038 20.4 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle AAA_23 PF13476.6 GBG85753.1 - 0.083 13.4 3.5 8.5 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain MotA_ExbB PF01618.16 GBG85753.1 - 5.2 6.8 6.4 0.52 10.1 0.0 2.4 2 1 0 2 2 2 0 MotA/TolQ/ExbB proton channel family SID-1_RNA_chan PF13965.6 GBG85755.1 - 4.1 5.7 27.3 5.1 5.4 27.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CitMHS PF03600.16 GBG85755.1 - 5.1 6.2 33.1 6.4 5.9 33.1 1.2 1 0 0 1 1 1 0 Citrate transporter ABC2_membrane PF01061.24 GBG85757.1 - 7.8e-42 143.1 19.1 1.4e-41 142.3 19.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GBG85757.1 - 4.1e-29 101.8 0.0 6.9e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG85757.1 - 4e-08 33.4 0.2 0.0065 16.3 0.2 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 GBG85757.1 - 1.1e-07 31.3 11.3 1.1e-07 31.3 11.3 1.9 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 GBG85757.1 - 7.9e-06 25.5 0.1 1.7e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG85757.1 - 1.1e-05 25.9 0.1 2.8e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GBG85757.1 - 0.00014 21.8 0.4 0.00027 20.9 0.1 1.6 2 0 0 2 2 1 1 RsgA GTPase SMC_N PF02463.19 GBG85757.1 - 0.0014 18.1 0.1 0.098 12.1 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GBG85757.1 - 0.0022 18.6 0.1 0.0022 18.6 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 GBG85757.1 - 0.0036 17.6 0.1 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GBG85757.1 - 0.012 15.7 0.1 0.023 14.7 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 GBG85757.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MeaB PF03308.16 GBG85757.1 - 0.016 14.2 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 GBG85757.1 - 0.025 14.1 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GBG85757.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GBG85757.1 - 0.082 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GBG85757.1 - 0.11 12.6 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Dynamin family Cytidylate_kin PF02224.18 GBG85757.1 - 0.11 12.2 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 GBG85757.1 - 0.14 12.4 0.2 0.29 11.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GBG85757.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_ATPase PF09818.9 GBG85757.1 - 0.14 10.9 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Orf78 PF06024.12 GBG85757.1 - 0.35 11.2 1.0 2 8.8 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) DUF2179 PF10035.9 GBG85758.1 - 0.11 12.3 0.0 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF4746 PF15928.5 GBG85758.1 - 3.4 7.0 14.5 9.2 5.6 14.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RVT_1 PF00078.27 GBG85759.1 - 2e-24 86.4 0.1 3.4e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG85759.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-4CXXC_R1 PF10497.9 GBG85760.1 - 3.6e-06 27.1 5.3 7.2e-06 26.2 5.3 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Myb_DNA-bind_4 PF13837.6 GBG85761.1 - 2e-09 37.7 3.8 4.7e-09 36.5 3.8 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG85761.1 - 0.00023 21.2 1.4 0.00051 20.1 1.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG85761.1 - 0.0045 17.2 1.7 0.029 14.6 1.3 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG85761.1 - 0.059 13.6 0.4 0.12 12.5 0.4 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG85761.1 - 0.99 9.8 8.1 0.32 11.3 4.4 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG85762.1 - 2.4e-08 34.0 0.0 4.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain E1_dh PF00676.20 GBG85763.1 - 3.4e-67 226.5 0.0 6.3e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 GBG85763.1 - 3.9e-67 225.3 0.0 6.4e-67 224.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 GBG85763.1 - 3.3e-49 166.5 0.0 6.8e-49 165.5 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 GBG85763.1 - 1.8e-16 59.4 0.1 4.4e-16 58.2 0.1 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus AAA_9 PF12781.7 GBG85763.1 - 0.044 12.9 0.1 0.081 12.0 0.1 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region ACD PF16671.5 GBG85763.1 - 0.56 8.5 2.7 0.96 7.7 2.7 1.3 1 0 0 1 1 1 0 Actin cross-linking domain zf-4CXXC_R1 PF10497.9 GBG85764.1 - 8.9e-29 99.6 13.3 2.7e-28 98.1 13.3 1.8 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF5622 PF18533.1 GBG85764.1 - 0.75 10.0 3.2 1.7 8.8 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) LRR_6 PF13516.6 GBG85765.1 - 1.2e-15 56.1 9.4 0.0052 16.7 0.0 6.3 6 0 0 6 6 6 4 Leucine Rich repeat Antimicrobial_2 PF08023.12 GBG85765.1 - 0.01 16.3 0.5 0.04 14.5 0.3 2.2 2 0 0 2 2 2 0 Frog antimicrobial peptide LRR_8 PF13855.6 GBG85765.1 - 0.051 13.3 8.2 0.83 9.5 1.5 4.0 1 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 GBG85765.1 - 0.2 12.1 13.1 1.3 9.6 0.4 4.1 3 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG85765.1 - 0.22 12.2 7.9 53 4.9 0.1 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_2 PF07723.13 GBG85765.1 - 0.28 11.9 1.1 11 6.9 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat RVT_1 PF00078.27 GBG85766.1 - 2.5e-29 102.4 0.1 4.8e-29 101.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85766.1 - 8.2e-05 22.6 0.0 0.00031 20.7 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85766.1 - 0.013 15.8 0.0 0.048 13.9 0.0 2.1 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Laminin_II PF06009.12 GBG85766.1 - 0.034 14.1 3.9 0.024 14.7 1.7 2.0 2 0 0 2 2 2 0 Laminin Domain II LXG PF04740.12 GBG85766.1 - 0.19 11.4 1.8 0.37 10.5 1.8 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily Exonuc_VII_L PF02601.15 GBG85766.1 - 0.62 9.6 9.1 1.1 8.8 7.6 2.1 2 1 0 2 2 2 0 Exonuclease VII, large subunit DUF1690 PF07956.11 GBG85766.1 - 2.2 8.7 6.3 13 6.2 1.1 2.7 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) SHMT PF00464.19 GBG85767.1 - 1.4e-182 606.8 0.0 1.7e-182 606.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase SHMT PF00464.19 GBG85768.1 - 8.1e-183 607.5 0.0 9.5e-183 607.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase IBN_N PF03810.19 GBG85769.1 - 1.4e-09 37.7 0.0 4.4e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.10 GBG85769.1 - 3.1e-09 36.2 0.4 2.2e-08 33.3 0.0 2.5 2 1 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 GBG85769.1 - 8.6e-06 24.5 1.2 0.013 14.0 0.0 2.8 2 1 1 3 3 3 2 CAS/CSE protein, C-terminus Xpo1 PF08389.12 GBG85769.1 - 7.9e-05 22.8 0.9 0.00031 20.8 0.1 2.5 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_EZ PF13513.6 GBG85769.1 - 0.0049 17.3 7.7 3.1 8.4 0.0 5.4 6 0 0 6 6 5 2 HEAT-like repeat RTP1_C1 PF10363.9 GBG85769.1 - 0.081 13.1 0.1 8.3 6.6 0.0 3.7 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3384 PF11864.8 GBG85769.1 - 0.082 11.8 0.0 1.7 7.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3384) DNA_pol_phi PF04931.13 GBG85769.1 - 2.5 6.1 17.3 4.7 5.2 17.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi PTPRCAP PF15713.5 GBG85769.1 - 2.6 8.3 11.3 4.9 7.4 11.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RRN3 PF05327.11 GBG85769.1 - 3.5 6.0 7.7 13 4.2 6.5 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 GBG85769.1 - 3.7 7.4 10.3 8.1 6.3 10.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 GBG85769.1 - 6.9 4.7 10.9 14 3.7 10.9 1.4 1 0 0 1 1 1 0 Nop14-like family IBN_N PF03810.19 GBG85770.1 - 1.1e-09 38.1 0.0 3.7e-09 36.4 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.10 GBG85770.1 - 4.1e-09 35.8 0.0 1.5e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Cse1 Xpo1 PF08389.12 GBG85770.1 - 2.4e-05 24.4 0.2 0.00026 21.1 0.1 2.7 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_EZ PF13513.6 GBG85770.1 - 0.00021 21.7 2.2 2.6 8.7 0.0 4.8 5 0 0 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 GBG85770.1 - 0.052 13.7 0.1 6.9 6.9 0.0 3.8 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 CAS_CSE1 PF03378.15 GBG85770.1 - 0.054 12.0 0.3 0.18 10.3 0.2 1.9 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus ParcG PF10274.9 GBG85770.1 - 0.16 12.1 0.0 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Parkin co-regulated protein 60KD_IMP PF02096.20 GBG85771.1 - 9e-51 172.1 0.1 1.3e-50 171.6 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Trp_syntA PF00290.20 GBG85771.1 - 0.1 11.5 0.1 0.23 10.3 0.1 1.5 1 0 0 1 1 1 0 Tryptophan synthase alpha chain LAP1C PF05609.12 GBG85771.1 - 2.2 7.3 4.6 0.54 9.3 0.1 1.8 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) RVT_1 PF00078.27 GBG85772.1 - 7.6e-32 110.6 0.0 1.3e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2805 PF10985.8 GBG85773.1 - 0.37 11.2 2.7 0.7 10.3 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Ank_2 PF12796.7 GBG85774.1 - 7.2e-05 23.3 0.4 0.081 13.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GBG85774.1 - 0.023 15.2 1.1 5.4 7.9 0.1 4.2 4 0 0 4 4 4 0 Ankyrin repeat CENP-B_dimeris PF09026.10 GBG85774.1 - 0.028 14.8 1.0 0.028 14.8 1.0 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CDC27 PF09507.10 GBG85775.1 - 0.59 9.5 22.4 1.3 8.3 22.4 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RT_RNaseH_2 PF17919.1 GBG85776.1 - 1.6e-48 162.8 0.0 8e-25 86.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85776.1 - 2.5e-36 124.1 0.0 5.7e-19 68.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85776.1 - 1.4e-34 119.5 0.5 2.9e-23 82.6 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG85776.1 - 1.9e-12 47.1 0.0 5.7e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG85776.1 - 0.029 14.7 0.1 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Nuc_deoxyrib_tr PF05014.15 GBG85776.1 - 0.16 12.0 0.0 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase SlyX PF04102.12 GBG85777.1 - 0.015 15.9 0.4 0.015 15.9 0.4 3.6 3 2 0 3 3 3 0 SlyX DUF2730 PF10805.8 GBG85777.1 - 0.071 13.2 0.9 0.43 10.7 0.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Tropomyosin PF00261.20 GBG85777.1 - 0.32 10.3 16.8 0.23 10.8 11.7 2.0 1 1 1 2 2 2 0 Tropomyosin DNA_Packaging PF11053.8 GBG85777.1 - 1.3 8.9 4.4 3.8 7.3 0.2 2.3 1 1 1 2 2 2 0 Terminase DNA packaging enzyme RVP_2 PF08284.11 GBG85778.1 - 5.2e-08 32.8 0.0 1.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG85778.1 - 1.8e-07 31.7 0.0 5e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85778.1 - 2.4e-05 24.8 0.0 5.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG85778.1 - 0.00054 19.7 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG85778.1 - 0.0064 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG85779.1 - 4.4e-21 74.8 0.0 6.7e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85779.1 - 2e-19 69.8 0.0 3.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85779.1 - 1.2e-08 34.7 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85780.1 - 2.3e-33 114.2 1.3 5.8e-25 87.2 0.0 2.4 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85780.1 - 2.8e-27 95.0 2.4 7.7e-13 48.6 1.9 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85780.1 - 1.2e-18 67.0 0.3 2.8e-18 65.8 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85780.1 - 3.4e-17 62.7 0.0 7.1e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG85780.1 - 2.2e-14 53.7 0.2 9e-14 51.7 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain rve_3 PF13683.6 GBG85780.1 - 0.011 15.4 0.1 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 Integrase core domain RVT_1 PF00078.27 GBG85781.1 - 8.2e-28 97.4 0.1 1.4e-27 96.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PSI_PsaH PF03244.14 GBG85781.1 - 0.04 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI Asp_protease_2 PF13650.6 GBG85782.1 - 1.4e-08 35.2 0.0 3.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85782.1 - 4.8e-08 32.9 0.0 8.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG85782.1 - 2.7e-07 31.1 0.0 5.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG85782.1 - 6.5e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG85783.1 - 4.2e-08 33.7 0.0 1.4e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85783.1 - 2.1e-07 30.8 0.0 5.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG85783.1 - 3.2e-06 27.6 0.0 1.2e-05 25.8 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG85783.1 - 0.0044 16.8 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG85783.1 - 0.0073 16.6 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG85784.1 - 3.7e-23 81.8 0.0 7.1e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85784.1 - 4.9e-23 81.1 0.0 9.3e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85784.1 - 3.4e-19 68.7 0.3 9.5e-19 67.3 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85784.1 - 6.1e-11 42.3 0.8 1.1e-10 41.5 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG85784.1 - 2.6e-10 40.5 0.0 9.3e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85784.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG85786.1 - 0.0047 17.2 0.6 0.6 10.4 0.1 2.6 2 0 0 2 2 2 2 Retrotransposon gag protein Complex1_49kDa PF00346.19 GBG85786.1 - 0.085 11.9 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RVT_1 PF00078.27 GBG85787.1 - 2.1e-23 83.0 0.0 4.1e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85787.1 - 2.3e-23 82.5 0.0 5.5e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85787.1 - 7.1e-22 77.3 0.0 1.6e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG85787.1 - 9.3e-09 35.2 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG85787.1 - 6.1e-06 26.8 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85787.1 - 2.9e-05 24.5 0.0 5.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG85787.1 - 0.00073 19.3 0.0 0.0021 17.9 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG85787.1 - 0.34 11.0 2.3 0.38 10.9 0.8 1.9 2 0 0 2 2 2 0 Integrase zinc binding domain RVT_1 PF00078.27 GBG85788.1 - 1.5e-34 119.5 0.1 2.4e-34 118.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85788.1 - 1e-28 99.7 0.0 2.3e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85788.1 - 4.5e-28 97.2 0.0 1.4e-27 95.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG85788.1 - 2.9 7.5 18.0 0.42 10.2 0.0 3.2 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase SlyX PF04102.12 GBG85789.1 - 0.0039 17.8 2.5 2.1 9.0 0.1 2.7 2 0 0 2 2 2 2 SlyX Retrotrans_gag PF03732.17 GBG85789.1 - 0.017 15.4 5.9 2.8 8.3 0.0 3.6 2 1 1 3 3 3 0 Retrotransposon gag protein CLZ PF16526.5 GBG85789.1 - 0.08 13.3 2.1 3 8.2 0.4 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 GBG85789.1 - 0.11 12.3 1.5 4.6 7.1 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator GPS2_interact PF15784.5 GBG85790.1 - 0.095 13.1 0.9 7.7 7.0 0.7 2.6 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF812 PF05667.11 GBG85790.1 - 0.1 11.4 3.4 0.2 10.5 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Taxilin PF09728.9 GBG85791.1 - 0.066 12.4 33.7 0.096 11.8 33.7 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein PRTP PF01366.18 GBG85791.1 - 3.6 5.5 9.4 4.8 5.1 9.4 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein OrfB_IS605 PF01385.19 GBG85791.1 - 4.7 7.4 15.3 0.53 10.5 0.6 3.0 3 1 0 3 3 3 0 Probable transposase Retrotrans_gag PF03732.17 GBG85792.1 - 0.00088 19.5 7.5 0.0031 17.7 0.1 3.8 3 1 0 3 3 3 1 Retrotransposon gag protein SPACA9 PF15120.6 GBG85792.1 - 0.089 12.6 2.5 0.14 11.9 1.0 2.0 2 1 1 3 3 3 0 Sperm acrosome-associated protein 9 LMBR1 PF04791.16 GBG85792.1 - 1.5 7.6 5.0 2.4 7.0 5.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein HIP1_clath_bdg PF16515.5 GBG85792.1 - 2.9 8.6 19.7 0.046 14.3 5.8 3.4 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RT_RNaseH_2 PF17919.1 GBG85793.1 - 6.6e-74 244.3 0.6 3.3e-26 91.2 0.1 4.8 5 0 0 5 5 5 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85793.1 - 2.1e-63 213.8 8.4 3.5e-32 111.7 0.1 4.5 3 1 1 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85793.1 - 6.3e-50 167.8 0.5 3.7e-24 85.0 0.0 4.3 4 0 0 4 4 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85793.1 - 1.5e-18 66.7 0.4 3.4e-18 65.5 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG85793.1 - 1.8e-08 34.9 0.0 6e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85793.1 - 5e-06 27.0 0.0 1.7e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG85793.1 - 0.00021 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85793.1 - 0.00035 20.3 0.0 0.00087 19.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG85793.1 - 0.011 16.0 0.0 0.011 16.0 0.0 3.9 4 0 0 4 4 3 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG85793.1 - 0.021 15.0 0.0 0.064 13.5 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DivIC PF04977.15 GBG85793.1 - 0.1 12.4 2.8 7.8 6.3 0.1 3.3 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 GBG85793.1 - 0.16 12.6 0.1 0.16 12.6 0.1 5.3 6 0 0 6 6 6 0 SlyX P4Ha_N PF08336.11 GBG85793.1 - 0.31 11.0 4.4 16 5.5 0.0 4.1 4 0 0 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region zf-CCHC PF00098.23 GBG85793.1 - 7.2 6.9 9.1 1.5 9.0 1.7 2.7 2 0 0 2 2 2 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG85794.1 - 3e-17 62.5 0.7 5.4e-17 61.6 0.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85794.1 - 4e-10 39.9 0.0 7.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85794.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 GBG85795.1 - 1.1e-07 31.7 0.0 2.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG85795.1 - 0.00032 21.3 0.0 0.00081 20.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85795.1 - 0.0025 18.3 0.1 0.0083 16.7 0.1 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG85795.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG85795.1 - 0.076 12.8 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease FAM60A PF15396.6 GBG85795.1 - 6.2 6.8 13.7 4.2 7.3 11.5 1.8 1 1 0 1 1 1 0 Protein Family FAM60A RVT_1 PF00078.27 GBG85796.1 - 1.1e-32 113.3 0.0 2.1e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG85796.1 - 7.8e-09 36.1 0.5 7.8e-09 36.1 0.5 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85797.1 - 7.5e-35 119.0 0.0 1.4e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85797.1 - 1.8e-30 106.1 0.0 3.6e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85797.1 - 2e-29 102.0 0.6 8.6e-29 99.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85797.1 - 5.5e-05 23.3 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG85797.1 - 0.0006 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG85797.1 - 0.0012 18.8 0.4 0.0027 17.6 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Kri1 PF05178.12 GBG85798.1 - 1.5 9.4 32.2 4.9 7.8 15.2 2.7 2 0 0 2 2 2 0 KRI1-like family RVT_1 PF00078.27 GBG85801.1 - 9.1e-58 195.4 0.6 3e-29 102.1 0.2 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85801.1 - 2.6e-32 110.8 0.1 2.5e-13 49.9 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85801.1 - 3.2e-19 69.2 0.0 8.3e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85801.1 - 3.2e-13 49.6 0.0 8.5e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG85801.1 - 7e-08 33.0 0.0 0.011 16.4 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG85801.1 - 1.1e-07 32.3 0.0 5.8e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG85801.1 - 0.0014 18.8 0.0 0.0046 17.2 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG85801.1 - 0.0019 18.0 0.0 0.051 13.4 0.0 2.4 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG85801.1 - 0.16 11.8 0.2 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease AAA_11 PF13086.6 GBG85801.1 - 1.9 8.2 6.1 3.4 7.4 6.1 1.3 1 0 0 1 1 1 0 AAA domain DUF4355 PF14265.6 GBG85801.1 - 7.8 6.8 25.2 15 5.8 25.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) zf-CCHC PF00098.23 GBG85803.1 - 5.9e-07 29.3 1.9 1.1e-06 28.5 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG85803.1 - 0.0015 18.3 0.4 0.0026 17.6 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG85803.1 - 0.21 11.4 1.6 0.43 10.4 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Swi5 PF07061.11 GBG85803.1 - 2.8 8.1 12.5 4.9 7.3 0.3 4.1 3 1 0 3 3 3 0 Swi5 DUF5320 PF17253.2 GBG85803.1 - 3.1 8.9 8.7 5 8.3 0.1 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5320) TRAP-gamma PF07074.12 GBG85803.1 - 6.2 6.4 5.0 11 5.5 5.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) rve PF00665.26 GBG85804.1 - 7.4e-16 58.4 0.9 1.6e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG85804.1 - 5.8e-15 55.4 0.1 1e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85804.1 - 0.00036 20.5 0.0 0.00086 19.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG85804.1 - 0.022 15.1 0.2 0.13 12.6 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG85804.1 - 0.19 12.3 0.1 0.19 12.3 0.1 2.4 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG85807.1 - 2.5e-29 101.3 0.0 4.3e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85807.1 - 1.5e-26 92.7 0.0 2.5e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG85807.1 - 3.2e-17 62.8 0.0 6.8e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG85807.1 - 2.1e-16 59.8 3.9 4.7e-14 52.2 0.1 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG85807.1 - 0.0031 17.7 0.2 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger zf-CCHC_4 PF14392.6 GBG85809.1 - 0.093 12.5 1.8 0.2 11.4 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG85810.1 - 3.6e-37 128.0 0.0 5.7e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gpUL132 PF11359.8 GBG85810.1 - 0.21 11.1 0.0 0.45 10.0 0.0 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 gag-asp_proteas PF13975.6 GBG85811.1 - 0.00036 21.0 0.0 0.00079 19.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85811.1 - 0.0015 19.1 0.0 0.0042 17.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG85811.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 GBG85811.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG85812.1 - 6.7e-26 90.3 0.0 3.6e-25 87.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85812.1 - 1.1e-25 90.0 0.0 3.1e-25 88.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85812.1 - 3.8e-23 82.2 0.2 1.3e-20 73.9 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG85812.1 - 5.5e-23 81.4 0.0 1.1e-06 29.1 0.0 3.6 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.6 GBG85812.1 - 8.7e-23 80.7 0.0 9.7e-06 26.1 0.0 3.7 3 0 0 3 3 3 3 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG85812.1 - 5.6e-20 71.5 0.0 7.7e-09 35.4 0.0 3.6 3 0 0 3 3 3 3 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG85812.1 - 6.1e-15 55.1 0.1 1.5e-14 53.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG85812.1 - 8.1e-13 48.3 0.0 0.0046 16.7 0.0 3.4 3 0 0 3 3 3 3 Aspartyl protease DUF1758 PF05585.12 GBG85812.1 - 0.00014 21.6 0.1 0.041 13.7 0.0 3.3 3 0 0 3 3 3 1 Putative peptidase (DUF1758) Retrotrans_gag PF03732.17 GBG85812.1 - 0.048 13.9 0.0 0.23 11.7 0.0 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein RVP PF00077.20 GBG85812.1 - 0.18 12.2 0.0 16 5.9 0.0 3.0 3 0 0 3 3 3 0 Retroviral aspartyl protease TolA_bind_tri PF16331.5 GBG85812.1 - 2.7 8.1 6.2 2.1 8.5 3.5 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation SlyX PF04102.12 GBG85812.1 - 3.3 8.4 8.7 1.3 9.7 0.3 3.9 4 0 0 4 4 4 0 SlyX Exo_endo_phos PF03372.23 GBG85813.1 - 0.012 15.1 0.0 0.056 12.9 0.0 2.1 1 1 1 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG85813.1 - 0.038 13.8 0.0 0.18 11.7 0.0 2.2 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase SEC-C PF02810.15 GBG85814.1 - 6.8e-10 38.7 14.8 1.1e-09 38.1 14.8 1.3 1 0 0 1 1 1 1 SEC-C motif rve PF00665.26 GBG85815.1 - 5.7e-13 49.1 0.0 1.3e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG85816.1 - 1.2e-23 83.1 0.0 5.2e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85816.1 - 1.1e-22 80.3 0.0 3.5e-22 78.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85816.1 - 2.4e-19 69.2 0.1 5.9e-19 67.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG85816.1 - 7.7e-07 28.9 0.6 1.7e-06 27.8 0.2 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG85816.1 - 0.01 16.0 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger SRP_SPB PF02978.19 GBG85817.1 - 0.04 14.5 0.0 0.11 13.1 0.0 1.8 2 0 0 2 2 2 0 Signal peptide binding domain Alfin PF12165.8 GBG85817.1 - 0.25 11.0 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Alfin Methyltransf_22 PF13383.6 GBG85818.1 - 3.1e-15 56.4 0.2 8.4e-15 55.0 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_21 PF05050.12 GBG85818.1 - 0.0027 17.7 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain PMSR PF01625.21 GBG85819.1 - 4e-42 144.0 0.2 5.2e-42 143.6 0.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase TPR_10 PF13374.6 GBG85819.1 - 0.12 12.3 0.0 0.55 10.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Beta-lactamase PF00144.24 GBG85821.1 - 1.6e-43 149.2 0.0 3.8e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase DUF659 PF04937.15 GBG85821.1 - 2.3e-29 102.2 0.1 3.5e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2052 PF09747.9 GBG85821.1 - 0.0067 16.6 14.7 0.018 15.2 14.7 1.7 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) RNA_pol_3_Rpc31 PF11705.8 GBG85821.1 - 0.098 12.9 18.0 0.24 11.6 18.0 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 GBG85821.1 - 0.19 11.5 10.4 0.55 10.0 10.4 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleo_P87 PF07267.11 GBG85821.1 - 0.67 8.7 8.9 1.4 7.7 8.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mpp10 PF04006.12 GBG85821.1 - 0.7 8.3 20.2 1.1 7.7 20.2 1.1 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 GBG85821.1 - 1.8 6.6 23.7 2.7 6.0 23.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG85821.1 - 1.9 6.6 19.2 2.8 6.0 19.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 GBG85821.1 - 2.1 7.7 5.1 5.3 6.3 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SDA1 PF05285.12 GBG85821.1 - 2.7 7.4 21.9 5.4 6.3 21.9 1.4 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 GBG85821.1 - 8 6.0 15.3 17 4.9 15.3 1.5 1 0 0 1 1 1 0 PPP4R2 CPSF100_C PF13299.6 GBG85821.1 - 9.1 6.4 7.1 25 5.0 7.1 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RVT_1 PF00078.27 GBG85823.1 - 2.9e-29 102.2 0.1 4.6e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85823.1 - 9.8e-20 70.8 0.0 2.5e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Alpha-amylase_C PF02806.18 GBG85823.1 - 6e-16 58.7 0.0 1.3e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain RT_RNaseH_2 PF17919.1 GBG85823.1 - 6.9e-15 54.9 0.0 2.7e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85823.1 - 6.3e-12 45.4 2.1 1.3e-11 44.4 0.2 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG85823.1 - 0.017 14.9 0.1 0.043 13.6 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG85824.1 - 2e-28 99.4 0.1 4.2e-28 98.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG85824.1 - 2.8e-14 52.9 0.1 8.2e-14 51.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG85824.1 - 2.7e-12 46.9 0.1 1.4e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG85824.1 - 4.3e-08 33.6 0.0 2e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85824.1 - 1.4e-07 32.0 0.0 3.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85824.1 - 8.2e-07 28.9 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG85824.1 - 1.7e-06 28.0 0.0 4.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG85824.1 - 1.8e-05 24.5 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG85824.1 - 2.3e-05 24.6 0.0 6.3e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG85824.1 - 0.0071 16.6 0.1 0.027 14.8 0.1 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein Histone_HNS PF00816.21 GBG85824.1 - 0.029 15.2 8.9 0.26 12.1 0.6 2.8 2 0 0 2 2 2 0 H-NS histone family CBM_48 PF02922.18 GBG85825.1 - 3.1e-08 33.8 1.4 3.2e-08 33.8 0.1 1.7 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AMPK1_CBM PF16561.5 GBG85825.1 - 0.16 12.2 0.2 0.32 11.2 0.2 1.4 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase GerE PF00196.19 GBG85826.1 - 0.0033 16.9 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, luxR family RT_RNaseH PF17917.1 GBG85827.1 - 5.9e-21 74.7 0.0 1.2e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85827.1 - 2.4e-16 59.6 0.6 2.4e-15 56.4 0.0 2.9 4 0 0 4 4 4 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG85827.1 - 3.7e-12 46.2 0.0 7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG85827.1 - 6.9e-10 38.7 0.0 1.8e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG85827.1 - 7.7e-05 22.9 0.1 0.00055 20.1 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG85827.1 - 0.00014 22.0 0.0 0.00032 20.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Glycos_transf_1 PF00534.20 GBG85830.1 - 4.7e-09 36.0 0.0 8.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG85830.1 - 1.8e-08 34.9 0.0 3.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG85830.1 - 0.037 14.4 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF4618 PF15397.6 GBG85830.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF3824 PF12868.7 GBG85832.1 - 0.16 12.6 2.3 1 10.0 2.3 2.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) ATE_N PF04376.13 GBG85833.1 - 0.039 14.3 0.3 0.42 11.0 0.0 2.5 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus Topo_Zn_Ribbon PF08272.11 GBG85833.1 - 0.34 10.6 2.1 0.34 10.6 0.2 2.0 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG85833.1 - 0.46 10.6 1.9 0.89 9.8 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG85834.1 - 4.5e-12 45.9 0.0 2.4e-10 40.3 0.0 2.6 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85834.1 - 1.4e-10 41.1 0.0 2.1e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Plant transposon protein Acetyltransf_1 PF00583.25 GBG85836.1 - 8.2e-11 42.2 0.0 2.3e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GBG85836.1 - 2.4e-05 24.2 0.1 7.9e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG85836.1 - 0.00045 20.1 0.0 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 GBG85836.1 - 0.0041 17.5 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GBG85836.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Q_salvage PF10343.9 GBG85837.1 - 3.6e-83 279.4 1.2 8.9e-72 242.0 0.0 2.8 2 1 0 3 3 3 2 Potential Queuosine, Q, salvage protein family Keratin_B2_2 PF13885.6 GBG85837.1 - 0.69 9.9 4.2 1.8 8.6 4.2 1.6 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Otopetrin PF03189.13 GBG85837.1 - 1.4 7.6 0.0 1.4 7.6 0.0 3.4 1 1 2 3 3 3 0 Otopetrin DAP3 PF10236.9 GBG85838.1 - 2.2e-29 102.7 0.0 2.3e-28 99.3 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 GBG85838.1 - 0.066 13.6 0.0 0.2 12.1 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.7 GBG85838.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 GBG85838.1 - 0.17 12.2 0.0 0.97 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Plasmodium_Vir PF05795.11 GBG85839.1 - 0.0066 15.9 1.7 0.0066 15.9 1.7 2.3 2 1 1 3 3 3 1 Plasmodium vivax Vir protein SAPS PF04499.15 GBG85839.1 - 1.3 7.7 7.5 1.3 7.7 7.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.6 GBG85839.1 - 2.2 6.9 10.1 3.2 6.4 10.1 1.3 1 0 0 1 1 1 0 Raftlin V_ATPase_I PF01496.19 GBG85839.1 - 5.1 4.9 12.9 1.2e+02 0.3 0.0 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Methyltransf_28 PF02636.17 GBG85840.1 - 1.4e-53 182.2 0.0 2.6e-53 181.4 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RVT_1 PF00078.27 GBG85841.1 - 9.4e-36 123.4 0.1 1.4e-35 122.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LysM PF01476.20 GBG85842.1 - 1e-35 121.5 0.0 8.1e-09 35.4 0.0 4.3 4 0 0 4 4 4 4 LysM domain DUF5102 PF17104.5 GBG85842.1 - 0.25 11.3 0.6 0.49 10.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Glyco_transf_29 PF00777.18 GBG85843.1 - 1.5e-08 34.4 0.0 1.5e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) RVT_1 PF00078.27 GBG85845.1 - 2.2e-29 102.6 0.1 3.4e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85845.1 - 1.5e-26 92.3 0.0 3.2e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85845.1 - 1.3e-23 83.2 0.0 2.2e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85845.1 - 3.7e-16 59.0 1.0 1.5e-15 57.0 0.2 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG85845.1 - 0.016 15.4 0.3 0.039 14.2 0.3 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG85846.1 - 2.3e-09 37.1 0.0 4.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG85848.1 - 3.6e-07 30.4 10.9 0.0031 17.7 0.0 4.5 4 0 0 4 4 4 2 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG85848.1 - 0.0042 17.1 12.2 0.049 13.7 0.9 4.1 3 0 0 3 3 3 2 TolA binding protein trimerisation DUF1664 PF07889.12 GBG85848.1 - 0.0059 16.6 1.1 0.0059 16.6 1.1 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF1664) TRPM_tetra PF16519.5 GBG85848.1 - 0.011 15.8 1.7 5.6 7.2 0.0 4.0 4 0 0 4 4 4 0 Tetramerisation domain of TRPM HIP1_clath_bdg PF16515.5 GBG85848.1 - 0.017 15.7 4.1 0.017 15.7 4.1 4.9 4 1 1 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Beta_helix PF13229.6 GBG85849.1 - 4.5e-09 36.4 2.2 4.4e-08 33.1 2.2 2.1 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG85849.1 - 0.00066 20.0 3.0 4 8.1 0.0 5.4 6 0 0 6 6 6 1 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Dr_adhesin PF12393.8 GBG85849.1 - 0.43 10.9 2.6 1.2 9.6 2.6 1.7 1 0 0 1 1 1 0 Dr family adhesin Mitofilin PF09731.9 GBG85850.1 - 0.025 13.5 29.1 0.026 13.4 29.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Mlo PF03094.15 GBG85854.1 - 1e-97 327.5 3.4 1.3e-97 327.2 3.4 1.0 1 0 0 1 1 1 1 Mlo family EAP30 PF04157.16 GBG85855.1 - 3.4e-38 131.3 0.1 4.3e-38 130.9 0.1 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 GBG85855.1 - 0.0023 18.1 0.0 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 Serglycin PF04360.12 GBG85855.1 - 1.1 9.2 5.5 2.2 8.2 5.5 1.5 1 0 0 1 1 1 0 Serglycin Yae1_N PF09811.9 GBG85856.1 - 2.8e-06 26.9 0.6 0.045 13.5 0.0 3.9 3 0 0 3 3 3 3 Essential protein Yae1, N terminal RVT_1 PF00078.27 GBG85858.1 - 6.2e-36 124.0 0.1 1.1e-35 123.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85858.1 - 6.8e-31 106.3 0.0 2.2e-30 104.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85858.1 - 5.5e-30 103.8 0.1 1.7e-29 102.2 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85859.1 - 2.4e-15 56.4 0.1 5.1e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG85859.1 - 0.0011 19.1 0.1 0.0058 16.8 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG85859.1 - 0.029 15.0 0.0 0.069 13.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG85859.1 - 0.08 13.5 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HSP70 PF00012.20 GBG85860.1 - 1.7e-85 287.5 0.0 2e-61 208.0 0.0 2.8 3 0 0 3 3 3 2 Hsp70 protein Ldh_1_C PF02866.18 GBG85860.1 - 6.1e-19 68.6 0.0 1.5e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GBG85860.1 - 2.8e-09 37.2 0.1 5.9e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain TIM PF00121.18 GBG85860.1 - 7e-08 32.1 0.0 0.041 13.2 0.0 3.6 4 0 0 4 4 4 3 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG85860.1 - 3.2e-07 29.5 0.0 7.1e-05 21.8 0.0 3.0 2 1 0 2 2 2 2 MreB/Mbl protein Myb_DNA-bind_4 PF13837.6 GBG85861.1 - 0.00059 20.2 0.6 0.0011 19.3 0.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH PF17917.1 GBG85862.1 - 1.6e-23 82.9 0.0 4e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85862.1 - 9.2e-23 80.2 0.0 2.2e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85862.1 - 0.00027 20.5 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG85863.1 - 5e-09 36.6 2.0 1.9e-08 34.8 0.0 3.0 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85863.1 - 1.3e-05 25.7 0.2 5.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG85863.1 - 0.001 18.8 0.3 0.0022 17.8 0.3 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85863.1 - 0.0023 18.2 0.0 0.0071 16.6 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG85863.1 - 0.0053 17.0 0.2 0.014 15.7 0.2 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein HSP70 PF00012.20 GBG85864.1 - 4.6e-142 474.2 0.0 5.7e-142 474.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85864.1 - 7.3e-12 44.8 0.3 2e-10 40.0 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein Methyltransf_14 PF08484.11 GBG85864.1 - 0.11 12.4 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain RVT_1 PF00078.27 GBG85865.1 - 2e-31 109.2 0.1 3.2e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85865.1 - 3.6e-29 100.7 0.0 1e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85865.1 - 7.6e-29 100.1 0.0 1.6e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG85865.1 - 0.008 15.8 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase SbcD_C PF12320.8 GBG85865.1 - 0.12 12.6 0.1 3.2 8.1 0.0 2.8 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain DUF4392 PF14336.6 GBG85865.1 - 0.23 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) HSP70 PF00012.20 GBG85866.1 - 1.2e-143 479.5 0.0 1.3e-143 479.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85866.1 - 8.7e-15 54.3 0.2 3.7e-13 49.0 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG85866.1 - 0.0021 17.9 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RVT_1 PF00078.27 GBG85867.1 - 4e-28 98.5 0.0 6.6e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85867.1 - 1.7e-26 92.2 0.0 1.3e-25 89.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85867.1 - 1.2e-23 83.4 0.0 3.4e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85867.1 - 2.3e-19 69.2 0.2 5.2e-19 68.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85867.1 - 4.5e-07 30.1 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85867.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger HSP70 PF00012.20 GBG85868.1 - 7e-84 282.1 0.0 5.7e-59 199.8 0.0 2.3 1 1 1 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG85868.1 - 3.3e-38 131.4 0.0 6.2e-12 45.4 0.0 6.8 6 1 0 6 6 6 5 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG85868.1 - 1.5e-09 37.2 0.3 8.9e-06 24.7 0.6 3.8 2 1 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.20 GBG85868.1 - 9.5e-06 25.3 0.0 0.0017 17.9 0.0 2.6 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FliG_C PF01706.16 GBG85868.1 - 0.039 14.1 0.0 1.5 9.0 0.0 3.0 2 0 0 2 2 2 0 FliG C-terminal domain DDR PF08841.10 GBG85868.1 - 0.3 10.0 3.3 9.6 5.1 0.0 3.5 4 0 0 4 4 4 0 Diol dehydratase reactivase ATPase-like domain DUF3046 PF11248.8 GBG85868.1 - 1.5 9.2 3.9 6 7.3 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3046) HSP70 PF00012.20 GBG85869.1 - 1.2e-37 129.5 0.0 2.1e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein TIM PF00121.18 GBG85869.1 - 1.1e-10 41.4 0.0 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Triosephosphate isomerase Asp_protease_2 PF13650.6 GBG85870.1 - 0.012 16.2 0.1 0.046 14.4 0.1 2.1 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG85870.1 - 0.02 15.4 0.0 0.11 13.1 0.0 2.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG85870.1 - 0.041 14.0 1.9 0.064 13.4 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG85870.1 - 0.1 12.3 0.2 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like HSP70 PF00012.20 GBG85871.1 - 3.4e-77 260.0 0.0 7.2e-58 196.2 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG85871.1 - 3.3e-10 39.3 0.4 6.2e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 GBG85871.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 StbA protein End3 PF12761.7 GBG85872.1 - 0.04 14.1 3.9 0.21 11.7 0.1 2.4 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 zf-CCHC PF00098.23 GBG85872.1 - 0.043 13.9 8.0 0.047 13.8 1.9 2.5 2 0 0 2 2 2 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG85874.1 - 0.41 11.1 2.3 0.71 10.3 0.3 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain TTc_toxin_rep PF18807.1 GBG85875.1 - 0.17 11.7 0.5 12 5.8 0.0 2.6 3 0 0 3 3 3 0 Tripartite Tc toxins repeat HSP70 PF00012.20 GBG85876.1 - 2.5e-147 491.6 0.0 3.1e-147 491.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85876.1 - 3.3e-08 32.7 0.0 5.4e-07 28.7 0.1 2.5 2 1 0 2 2 2 1 MreB/Mbl protein MutL PF13941.6 GBG85876.1 - 0.009 14.7 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 MutL protein FGGY_C PF02782.16 GBG85876.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG85876.1 - 0.027 14.9 0.0 3.7 8.0 0.0 3.2 2 1 0 2 2 2 0 Cell division protein FtsA PRP4 PF08799.11 GBG85876.1 - 0.082 12.5 3.1 0.54 9.9 0.1 3.5 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like HSP70 PF00012.20 GBG85877.1 - 9e-151 503.0 0.0 1e-150 502.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85877.1 - 1.1e-07 31.0 0.1 2.4e-06 26.6 0.2 2.4 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG85877.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG85877.1 - 0.015 15.7 0.0 3.1 8.3 0.0 3.0 2 2 0 2 2 2 0 Cell division protein FtsA PRP4 PF08799.11 GBG85877.1 - 0.034 13.7 0.2 0.35 10.5 0.1 2.3 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like HSP70 PF00012.20 GBG85879.1 - 1.8e-145 485.5 0.0 2.1e-145 485.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85879.1 - 1e-10 41.0 0.0 6.3e-10 38.4 0.0 2.2 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG85879.1 - 0.00038 20.2 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Raco_middle PF17651.1 GBG85879.1 - 0.019 14.7 0.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 RACo middle region Hydantoinase_A PF01968.18 GBG85879.1 - 0.12 11.6 0.0 0.78 8.9 0.0 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HSP70 PF00012.20 GBG85880.1 - 2.4e-142 475.2 0.0 3.1e-142 474.8 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85880.1 - 1.2e-10 40.8 1.5 1.5e-09 37.1 1.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GBG85880.1 - 0.0034 17.8 0.1 2.3 8.7 0.0 2.7 2 0 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.16 GBG85880.1 - 0.0041 16.9 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 GBG85881.1 - 6.5e-187 622.4 13.6 4.6e-68 229.9 0.0 5.0 4 1 1 5 5 4 4 Hsp70 protein TIM PF00121.18 GBG85881.1 - 1.8e-25 89.7 0.0 5.2e-08 32.5 0.0 4.7 4 0 0 4 4 4 4 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG85881.1 - 3.6e-11 42.5 5.8 0.079 11.8 0.9 5.9 4 2 0 4 4 4 4 MreB/Mbl protein FtsA PF14450.6 GBG85881.1 - 0.0012 19.3 0.0 1e+02 3.4 0.0 4.6 4 0 0 4 4 4 0 Cell division protein FtsA DUF1281 PF06924.11 GBG85881.1 - 0.0068 16.0 0.3 15 5.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1281) NOA36 PF06524.12 GBG85881.1 - 0.069 12.5 7.4 0.12 11.7 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein DUF768 PF05589.11 GBG85881.1 - 0.1 12.6 0.6 48 4.1 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF768) CagX PF03524.15 GBG85881.1 - 0.16 11.7 0.1 0.39 10.4 0.1 1.6 2 0 0 2 2 2 0 Conjugal transfer protein FerI PF08151.12 GBG85881.1 - 0.19 11.8 0.1 42 4.3 0.0 2.8 2 0 0 2 2 2 0 FerI (NUC094) domain Paf1 PF03985.13 GBG85881.1 - 0.29 10.1 10.1 0.46 9.4 10.1 1.2 1 0 0 1 1 1 0 Paf1 Myc_N PF01056.18 GBG85881.1 - 0.31 10.9 6.8 0.58 10.0 6.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF4746 PF15928.5 GBG85881.1 - 1.6 8.1 10.1 2.8 7.3 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Radial_spoke PF04712.12 GBG85881.1 - 1.7 7.5 11.5 2.7 6.8 11.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein HSP70 PF00012.20 GBG85883.1 - 2.5e-149 498.3 0.0 3e-149 498.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85883.1 - 4.4e-07 29.0 0.3 6.2e-06 25.2 0.2 2.5 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG85883.1 - 0.00041 20.1 0.0 0.00099 18.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG85883.1 - 0.13 12.7 1.4 4.3 7.8 0.0 3.5 3 1 0 3 3 3 0 Cell division protein FtsA DMRL_synthase PF00885.19 GBG85883.1 - 0.16 11.8 0.2 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase HSP70 PF00012.20 GBG85884.1 - 4e-147 491.0 0.0 4.7e-147 490.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG85884.1 - 9.5e-10 37.8 0.0 4.8e-09 35.5 0.0 2.1 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG85884.1 - 0.00095 18.9 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Raco_middle PF17651.1 GBG85884.1 - 0.14 11.8 0.1 0.86 9.3 0.0 2.2 2 0 0 2 2 2 0 RACo middle region HSP70 PF00012.20 GBG85885.1 - 7.5e-85 285.3 0.0 3.1e-60 204.0 0.0 2.1 1 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG85885.1 - 2.3e-10 39.8 0.1 4.1e-07 29.1 0.2 3.2 3 1 0 3 3 3 2 MreB/Mbl protein TIM PF00121.18 GBG85885.1 - 6.1e-08 32.3 0.0 1.9e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 Triosephosphate isomerase HSP70 PF00012.20 GBG85886.1 - 1.7e-61 208.2 0.0 1.1e-38 132.8 0.0 2.2 1 1 1 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG85886.1 - 9.1e-09 35.0 0.0 5.3e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG85886.1 - 2.1e-06 26.8 0.2 0.0042 16.0 0.4 3.1 2 1 0 2 2 2 2 MreB/Mbl protein DUF4893 PF16233.5 GBG85887.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4893) HSP70 PF00012.20 GBG85888.1 - 8.3e-88 295.1 0.0 1.7e-59 201.5 0.0 2.5 1 1 1 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG85888.1 - 5.5e-25 88.1 0.0 1.4e-09 37.7 0.0 5.8 4 2 1 5 5 5 5 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG85888.1 - 3.1e-07 29.5 0.1 1.7e-05 23.8 0.0 3.4 3 1 0 3 3 3 1 MreB/Mbl protein DUF2408 PF10303.9 GBG85888.1 - 0.074 13.6 0.0 0.38 11.3 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Porin_5 PF16930.5 GBG85888.1 - 0.2 10.1 0.9 0.33 9.4 0.9 1.2 1 0 0 1 1 1 0 Putative porin DUF4600 PF15372.6 GBG85888.1 - 0.64 10.4 3.8 33 4.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) Myco_haema PF05692.12 GBG85890.1 - 0.046 12.7 1.9 0.05 12.6 1.9 1.1 1 0 0 1 1 1 0 Mycoplasma haemagglutinin DUF3629 PF12302.8 GBG85890.1 - 1.2 8.5 9.7 1.7 8.1 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) FAM60A PF15396.6 GBG85890.1 - 3.4 7.6 7.5 3.7 7.5 7.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Pep3_Vps18 PF05131.14 GBG85891.1 - 1.5e-21 76.8 1.2 8.6e-10 38.6 0.0 2.4 1 1 1 2 2 2 2 Pep3/Vps18/deep orange family DUF982 PF06169.12 GBG85891.1 - 0.14 12.2 3.2 0.63 10.1 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF982) TPR_7 PF13176.6 GBG85891.1 - 0.95 9.7 4.4 1 9.5 0.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG85891.1 - 1.8 8.9 9.9 4.9 7.5 3.2 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG85891.1 - 4.1 7.4 6.2 4.9 7.1 0.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Herpes_BLRF2 PF05812.12 GBG85892.1 - 0.074 13.2 6.7 0.17 12.0 1.0 2.9 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein KASH_CCD PF14662.6 GBG85892.1 - 0.31 10.8 23.1 0.027 14.3 6.5 2.9 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH HOOK PF05622.12 GBG85892.1 - 1.4 7.0 25.4 49 1.9 25.4 2.4 1 1 0 1 1 1 0 HOOK protein PCRF PF03462.18 GBG85892.1 - 1.7 8.5 12.3 1 9.2 1.3 2.8 3 0 0 3 3 3 0 PCRF domain HAUS-augmin3 PF14932.6 GBG85892.1 - 3.6 7.1 19.2 0.5 9.9 8.9 3.4 2 2 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2205 PF10224.9 GBG85892.1 - 4.5 7.4 9.0 4.3 7.4 0.6 3.8 3 1 0 3 3 3 0 Short coiled-coil protein RVT_1 PF00078.27 GBG85894.1 - 5e-52 176.6 0.6 9.3e-28 97.3 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85894.1 - 4.1e-41 139.1 0.1 1.5e-23 82.7 0.0 3.9 3 1 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85894.1 - 2.2e-39 134.0 1.5 1.1e-21 77.1 0.0 3.4 3 1 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85894.1 - 6.3e-30 103.1 4.4 3.1e-14 52.8 0.1 3.0 3 0 0 3 3 3 2 Integrase zinc binding domain rve PF00665.26 GBG85894.1 - 5.4e-14 52.4 0.1 1.4e-06 28.5 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain RVP_2 PF08284.11 GBG85894.1 - 9.4e-11 41.6 0.0 1.1e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG85894.1 - 2.4e-07 31.3 0.0 1.6e-06 28.7 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85894.1 - 1.1e-06 29.1 0.0 0.0001 22.8 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG85894.1 - 0.0039 17.1 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG85894.1 - 0.01 16.0 0.2 0.12 12.6 0.1 2.5 2 0 0 2 2 2 0 H2C2 zinc finger Asp_protease PF09668.10 GBG85894.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Integrin_b_cyt PF08725.11 GBG85894.1 - 0.099 12.3 2.9 7.6 6.3 0.0 3.1 3 0 0 3 3 3 0 Integrin beta cytoplasmic domain ECH_1 PF00378.20 GBG85895.1 - 1.5e-73 247.2 0.0 2e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GBG85895.1 - 1.2e-19 71.0 0.0 1.6e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 GBG85895.1 - 0.03 13.3 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Peptidase_S49 PF01343.18 GBG85895.1 - 0.093 12.7 0.1 2 8.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 Cation_ATPase_C PF00689.21 GBG85897.1 - 9.5e-49 165.6 3.6 9.5e-49 165.6 3.6 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GBG85897.1 - 1.9e-48 164.4 0.3 1.9e-48 164.4 0.3 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GBG85897.1 - 8e-21 75.3 2.1 1.6e-19 71.0 2.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GBG85897.1 - 4.3e-20 71.2 0.0 1.1e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GBG85897.1 - 3.5e-19 68.7 0.0 6.6e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 GBG85897.1 - 1.4e-05 25.6 0.0 2.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GBG85897.1 - 3.7e-05 23.6 1.5 0.0016 18.3 2.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ABC-3 PF00950.17 GBG85897.1 - 0.0075 15.8 0.9 0.021 14.3 0.9 1.7 1 0 0 1 1 1 1 ABC 3 transport family Rho_N PF07498.12 GBG85898.1 - 3e-07 30.3 0.0 6.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Nop14 PF04147.12 GBG85900.1 - 0.42 8.8 12.0 0.53 8.4 12.0 1.2 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 GBG85900.1 - 1.3 9.3 11.0 0.085 13.1 6.1 1.5 2 0 0 2 2 2 0 Sodium ion transport-associated SQAPI PF16845.5 GBG85901.1 - 1.1e-09 38.5 0.2 2e-09 37.6 0.0 1.5 2 0 0 2 2 2 1 Aspartic acid proteinase inhibitor Cystatin PF00031.21 GBG85901.1 - 2.9e-09 37.1 0.0 5.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Cystatin domain GOLD_2 PF13897.6 GBG85902.1 - 4.6 7.7 6.3 7.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF659 PF04937.15 GBG85903.1 - 5.7e-17 62.0 0.0 9.8e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG85903.1 - 0.00062 19.5 1.7 0.0046 16.7 0.1 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF5559 PF17714.1 GBG85903.1 - 0.083 12.8 2.5 0.82 9.5 0.0 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5559) Dimer_Tnp_hAT PF05699.14 GBG85904.1 - 0.00016 21.4 0.1 0.00081 19.1 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region PAN_4 PF14295.6 GBG85905.1 - 0.00068 19.5 2.4 0.0015 18.4 2.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 GBG85905.1 - 0.7 9.9 5.5 0.089 12.8 1.1 1.8 2 0 0 2 2 2 0 PAN domain PAN_4 PF14295.6 GBG85906.1 - 0.00024 21.0 2.1 0.00039 20.3 2.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 GBG85906.1 - 0.02 14.9 1.1 0.025 14.5 1.1 1.2 1 0 0 1 1 1 0 PAN domain zf-CCHC PF00098.23 GBG85907.1 - 0.013 15.5 1.5 0.025 14.6 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF572 PF04502.13 GBG85907.1 - 0.04 13.6 13.3 0.048 13.3 13.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SurA_N_3 PF13624.6 GBG85907.1 - 8.4 6.2 9.0 15 5.4 9.0 1.4 1 0 0 1 1 1 0 SurA N-terminal domain NinG PF05766.12 GBG85907.1 - 9.9 6.0 10.8 5.1 7.0 8.3 1.8 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein RT_RNaseH_2 PF17919.1 GBG85908.1 - 1e-17 64.0 0.0 2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85908.1 - 1.7e-13 50.6 0.1 2.4e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85908.1 - 3.7e-06 27.2 0.0 6.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BUD22 PF09073.10 GBG85908.1 - 1.6 8.0 33.7 2.5 7.4 33.7 1.1 1 0 0 1 1 1 0 BUD22 gag-asp_proteas PF13975.6 GBG85909.1 - 3.4e-07 30.7 0.1 7.4e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85909.1 - 6.9e-05 23.4 0.1 0.00016 22.3 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG85909.1 - 0.00063 19.5 0.0 0.00098 18.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85909.1 - 0.044 13.6 0.1 0.065 13.0 0.1 1.2 1 0 0 1 1 1 0 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG85910.1 - 1e-30 106.5 0.0 1.5e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85910.1 - 3.5e-13 49.6 0.0 5.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85910.1 - 1.3e-05 24.9 0.3 0.0096 15.6 0.0 2.3 1 1 1 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG85910.1 - 0.095 13.1 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG85911.1 - 2.4e-28 98.8 0.0 3.2e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85911.1 - 2.5e-12 46.9 0.0 3.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85911.1 - 0.00023 20.9 0.2 0.4 10.3 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG85911.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain DUF659 PF04937.15 GBG85912.1 - 2.1e-16 60.1 0.2 4.7e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG85912.1 - 2.1e-06 27.4 0.0 4.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_Tnp_4 PF13359.6 GBG85913.1 - 1e-18 67.5 0.0 1.6e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85913.1 - 1.5e-07 31.3 0.0 3e-07 30.3 0.0 1.4 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG85913.1 - 0.022 14.4 0.1 19 4.8 0.0 3.0 3 0 0 3 3 3 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG85913.1 - 0.032 14.6 0.1 2.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain Ammonium_transp PF00909.21 GBG85914.1 - 1.1e-122 409.6 28.0 1.3e-122 409.4 28.0 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family SPT_ssu-like PF11779.8 GBG85914.1 - 4.7 6.9 9.2 0.12 12.0 0.3 3.0 3 0 0 3 3 3 0 Small subunit of serine palmitoyltransferase-like RVT_1 PF00078.27 GBG85915.1 - 2e-31 109.3 0.1 3.7e-31 108.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85915.1 - 1.8e-28 98.9 0.0 3.9e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85915.1 - 1.7e-27 95.3 0.0 3.6e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85915.1 - 1.9e-17 63.1 0.6 4.9e-17 61.8 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85915.1 - 2e-16 60.2 0.0 4.7e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85915.1 - 0.045 14.0 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG85915.1 - 0.072 13.0 0.0 0.23 11.4 0.0 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Mt_ATP_synt PF15704.5 GBG85916.1 - 0.0091 15.9 1.3 0.012 15.5 1.3 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase subunit Cas_APE2256 PF09651.10 GBG85916.1 - 0.038 13.9 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) THUMP PF02926.17 GBG85916.1 - 0.1 12.7 1.1 0.16 12.1 0.6 1.5 1 1 1 2 2 2 0 THUMP domain AT_hook PF02178.19 GBG85917.1 - 4.2 7.6 6.6 11 6.3 6.6 1.8 1 0 0 1 1 1 0 AT hook motif PPP4R2 PF09184.11 GBG85918.1 - 1 8.9 25.0 1 8.9 25.0 1.2 1 0 0 1 1 1 0 PPP4R2 CobT PF06213.12 GBG85918.1 - 2.5 7.4 27.0 2.7 7.3 27.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF5427 PF10310.9 GBG85918.1 - 6.5 5.6 22.2 7.2 5.4 22.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Zip PF02535.22 GBG85918.1 - 7.3 5.7 15.0 7.1 5.8 15.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 GBG85918.1 - 7.6 4.6 34.3 8.8 4.4 34.3 1.0 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 GBG85918.1 - 8.4 5.3 12.9 9.3 5.1 12.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Dimer_Tnp_hAT PF05699.14 GBG85919.1 - 2.9e-07 30.2 0.1 7e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG85919.1 - 0.0011 18.8 0.4 0.0034 17.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DDE_Tnp_4 PF13359.6 GBG85920.1 - 1.3e-23 83.4 0.0 2.1e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85920.1 - 3.8e-10 39.7 0.0 5.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG85920.1 - 0.054 13.9 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG85920.1 - 0.13 11.9 0.0 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain rve PF00665.26 GBG85921.1 - 5.4e-13 49.2 0.0 1.6e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG85921.1 - 1.3e-11 44.4 0.1 2.5e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG85921.1 - 1e-07 32.4 0.0 2.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85921.1 - 9.8e-05 22.9 0.0 0.00026 21.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG85921.1 - 0.0079 16.5 0.0 0.027 14.8 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG85921.1 - 0.078 12.8 0.5 0.14 11.9 0.5 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG85922.1 - 9.3e-14 51.5 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG85923.1 - 7.2e-11 42.0 0.0 2e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG85923.1 - 1.7e-09 37.9 0.0 4.8e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG85923.1 - 6.7e-08 32.5 0.1 2.1e-05 24.5 0.1 2.7 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85923.1 - 4.1e-07 30.3 0.0 2.2e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85923.1 - 0.024 14.1 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG85923.1 - 0.079 13.2 0.1 0.41 11.0 0.1 2.3 1 1 0 1 1 1 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG85923.1 - 0.16 12.6 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF924 PF06041.11 GBG85924.1 - 0.092 12.9 0.9 0.14 12.2 0.9 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) SEP PF08059.13 GBG85925.1 - 1.2e-28 99.4 0.0 4.1e-28 97.8 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 GBG85925.1 - 2.6e-13 50.0 0.0 4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 UBX domain DEAD PF00270.29 GBG85926.1 - 1.7e-33 115.8 0.0 4.3e-33 114.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG85926.1 - 3.2e-24 85.4 0.0 5.4e-23 81.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GBG85926.1 - 0.032 14.5 1.2 3.9 7.7 1.6 3.4 2 2 0 3 3 3 0 AAA domain ZapA PF05164.13 GBG85926.1 - 0.071 13.6 0.1 0.58 10.6 0.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapA HisG PF01634.18 GBG85927.1 - 1.7e-09 37.9 0.0 2.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase RT_RNaseH PF17917.1 GBG85928.1 - 2e-28 98.8 0.1 5e-28 97.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85928.1 - 4.1e-20 71.7 0.0 1.6e-19 69.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HisG PF01634.18 GBG85928.1 - 1.2e-19 70.9 0.0 2.7e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 GBG85928.1 - 2.8e-17 62.6 0.0 1.3e-16 60.5 0.0 2.2 1 0 0 1 1 1 1 HisG, C-terminal domain Integrase_H2C2 PF17921.1 GBG85928.1 - 4.1e-05 23.6 0.1 0.0001 22.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1758 PF05585.12 GBG85928.1 - 0.00068 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG85928.1 - 0.00093 19.8 0.0 0.0024 18.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG85928.1 - 0.0023 18.5 0.0 0.023 15.3 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG85928.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4392 PF14336.6 GBG85928.1 - 0.0085 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) Asp_protease PF09668.10 GBG85928.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Mt_ATP-synt_B PF05405.14 GBG85928.1 - 0.082 12.5 0.3 0.24 11.0 0.3 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Phage_GPO PF05929.11 GBG85928.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase tRNA_Me_trans PF03054.16 GBG85929.1 - 5.5e-93 311.6 0.0 3.9e-84 282.5 0.0 2.1 2 0 0 2 2 2 2 tRNA methyl transferase THB PF18362.1 GBG85930.1 - 0.019 14.5 0.1 0.043 13.4 0.1 1.6 1 0 0 1 1 1 0 Tri-helix bundle domain Lectin_N PF03954.14 GBG85930.1 - 0.073 12.8 7.3 0.41 10.4 5.7 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain FlaC_arch PF05377.11 GBG85930.1 - 3.8 8.0 7.9 2.6 8.5 0.2 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) zf-CCHC PF00098.23 GBG85931.1 - 1.2e-06 28.3 4.3 2.2e-06 27.5 4.3 1.5 1 0 0 1 1 1 1 Zinc knuckle BUD22 PF09073.10 GBG85931.1 - 3.3e-05 23.4 15.4 4.9e-05 22.9 15.4 1.2 1 0 0 1 1 1 1 BUD22 zf-CCHC_3 PF13917.6 GBG85931.1 - 0.0014 18.5 2.1 0.0014 18.5 2.1 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG85931.1 - 0.014 15.2 3.2 0.027 14.3 3.2 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF1682 PF07946.14 GBG85931.1 - 0.85 8.8 22.0 1.2 8.3 22.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 GBG85931.1 - 3.1 6.5 9.3 4.8 5.8 9.3 1.5 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GBG85931.1 - 4.4 7.0 14.5 8.6 6.1 14.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MSA-2c PF12238.8 GBG85932.1 - 0.1 12.6 5.0 0.3 11.1 0.3 3.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c RVT_1 PF00078.27 GBG85933.1 - 2.3e-07 30.6 0.0 3.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG85933.1 - 4.5e-05 24.1 5.1 4.5e-05 24.1 5.1 3.0 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase FlgD_ig PF13860.6 GBG85933.1 - 0.034 14.0 0.1 0.084 12.7 0.1 1.6 1 0 0 1 1 1 0 FlgD Ig-like domain RT_RNaseH_2 PF17919.1 GBG85935.1 - 1e-28 99.3 0.0 1.7e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85935.1 - 6.5e-25 87.4 0.0 9.8e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85935.1 - 3e-12 46.5 0.0 4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIF_alpha PF05793.12 GBG85935.1 - 0.053 12.1 9.4 0.063 11.9 9.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPP4R2 PF09184.11 GBG85935.1 - 0.69 9.5 13.8 1.1 8.8 13.8 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4746 PF15928.5 GBG85935.1 - 1.9 7.8 12.7 2.8 7.3 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BUD22 PF09073.10 GBG85935.1 - 3.2 7.0 13.7 4.5 6.5 13.7 1.1 1 0 0 1 1 1 0 BUD22 CUE PF02845.16 GBG85936.1 - 0.0012 18.5 0.0 0.004 16.8 0.0 2.0 1 0 0 1 1 1 1 CUE domain SpoIID PF08486.10 GBG85936.1 - 0.39 11.3 8.1 3.1 8.4 0.5 2.6 2 0 0 2 2 2 0 Stage II sporulation protein SlyX PF04102.12 GBG85936.1 - 0.45 11.2 1.9 1.8 9.2 0.0 2.7 2 0 0 2 2 2 0 SlyX FGGY_N PF00370.21 GBG85937.1 - 4.6e-20 72.2 0.0 5.9e-18 65.3 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_N PF00370.21 GBG85938.1 - 3e-14 53.2 0.0 6.2e-12 45.6 0.0 3.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain RVT_1 PF00078.27 GBG85939.1 - 2.2e-30 105.9 0.3 3.2e-30 105.3 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85939.1 - 6.5e-30 103.1 0.1 1.1e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG85939.1 - 1.1e-24 86.8 0.1 1.9e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG85939.1 - 0.00094 18.7 11.3 0.0015 18.0 11.3 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG85939.1 - 0.00095 17.5 11.8 0.0013 17.1 11.8 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 GBG85939.1 - 0.0053 15.1 9.0 0.0074 14.6 9.0 1.2 1 0 0 1 1 1 1 CDC45-like protein PPP4R2 PF09184.11 GBG85939.1 - 0.0056 16.3 13.9 0.0087 15.7 13.9 1.2 1 0 0 1 1 1 1 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 GBG85939.1 - 0.025 14.9 17.5 0.048 13.9 17.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.13 GBG85939.1 - 0.048 13.5 13.6 0.096 12.6 13.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.12 GBG85939.1 - 0.086 12.2 14.8 0.13 11.7 14.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 GBG85939.1 - 0.095 11.1 14.1 0.14 10.5 14.1 1.2 1 0 0 1 1 1 0 Mpp10 protein SGT1 PF07093.11 GBG85939.1 - 0.1 11.0 5.5 0.15 10.4 5.5 1.1 1 0 0 1 1 1 0 SGT1 protein Mcp5_PH PF12814.7 GBG85939.1 - 0.14 12.3 0.4 0.69 10.0 0.1 2.0 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology NOA36 PF06524.12 GBG85939.1 - 0.24 10.7 22.2 0.43 9.9 22.2 1.3 1 0 0 1 1 1 0 NOA36 protein RPA43_OB PF17875.1 GBG85939.1 - 0.4 11.3 1.9 0.99 10.0 1.9 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I TFIIA PF03153.13 GBG85939.1 - 0.74 9.7 11.2 1.1 9.2 11.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_Ag35 PF03286.14 GBG85939.1 - 0.88 9.3 9.1 0.15 11.8 5.1 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Utp14 PF04615.13 GBG85939.1 - 0.98 7.9 9.7 1.4 7.4 9.7 1.1 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 GBG85939.1 - 1.2 8.4 16.6 1.8 7.8 16.6 1.2 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 GBG85939.1 - 2 8.3 6.9 4.1 7.3 6.9 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop53 PF07767.11 GBG85939.1 - 2.3 7.5 12.6 4.1 6.7 12.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GCIP PF13324.6 GBG85939.1 - 2.6 7.6 7.0 4.3 6.9 7.0 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC27 PF09507.10 GBG85939.1 - 4.6 6.5 8.6 6.7 6.0 8.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Trypan_PARP PF05887.11 GBG85939.1 - 4.7 7.2 13.0 9.4 6.2 13.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.12 GBG85939.1 - 7 6.4 7.3 13 5.5 7.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2722 PF10846.8 GBG85939.1 - 7.4 5.4 5.2 11 4.8 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF1488 PF07369.11 GBG85940.1 - 0.49 10.4 2.0 1.7 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) DUF4140 PF13600.6 GBG85940.1 - 9.7 6.7 7.8 2.5 8.6 0.5 2.9 1 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Pyr_redox_2 PF07992.14 GBG85941.1 - 1.8e-45 155.5 2.4 2.3e-45 155.1 2.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GBG85941.1 - 3.9e-22 78.6 0.0 8.1e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GBG85941.1 - 9.9e-18 64.5 1.9 7.7e-13 48.8 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG85941.1 - 1.2e-10 41.1 0.8 2.7e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GBG85941.1 - 3.7e-08 32.9 5.1 3.7e-07 29.6 1.3 2.5 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 GBG85941.1 - 0.00029 19.6 0.5 0.00062 18.6 0.5 1.5 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 GBG85941.1 - 0.00078 18.7 0.3 0.0015 17.8 0.3 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 GBG85941.1 - 0.002 17.5 0.5 0.022 14.1 0.2 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GBG85941.1 - 0.002 17.6 2.3 0.0041 16.5 2.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 GBG85941.1 - 0.002 17.7 3.9 0.0048 16.5 1.5 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GBG85941.1 - 0.004 17.3 1.1 0.004 17.3 1.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GBG85941.1 - 0.021 13.9 2.3 0.035 13.2 2.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GBG85941.1 - 0.16 11.0 2.0 0.28 10.2 0.9 1.8 1 1 1 2 2 2 0 Lycopene cyclase protein Histone PF00125.24 GBG85942.1 - 2.7e-54 183.0 1.9 3e-54 182.9 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 GBG85942.1 - 0.00013 22.6 1.7 0.00015 22.3 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 GBG85942.1 - 0.00018 21.6 0.5 0.00028 21.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GBG85942.1 - 0.00075 19.8 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GBG85942.1 - 0.02 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GBG85942.1 - 0.057 13.5 0.1 0.11 12.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit MADF_DNA_bdg PF10545.9 GBG85943.1 - 0.0024 18.1 0.6 0.006 16.9 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 GBG85943.1 - 0.18 12.2 2.1 0.52 10.7 0.2 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG85945.1 - 2.9e-21 75.8 0.0 4.4e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG85945.1 - 2.7e-07 30.4 0.0 4.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DUF2961 PF11175.8 GBG85945.1 - 0.039 13.6 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) DDE_Tnp_1 PF01609.21 GBG85945.1 - 0.18 11.4 0.1 0.83 9.3 0.1 2.1 1 1 1 2 2 2 0 Transposase DDE domain Histone PF00125.24 GBG85946.1 - 2.7e-54 183.0 1.9 3e-54 182.9 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 GBG85946.1 - 0.00013 22.6 1.7 0.00015 22.3 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 GBG85946.1 - 0.00018 21.6 0.5 0.00028 21.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GBG85946.1 - 0.00075 19.8 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GBG85946.1 - 0.02 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GBG85946.1 - 0.057 13.5 0.1 0.11 12.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 GBG85947.1 - 2.7e-54 183.0 1.9 3e-54 182.9 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 GBG85947.1 - 0.00013 22.6 1.7 0.00015 22.3 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 GBG85947.1 - 0.00018 21.6 0.5 0.00028 21.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GBG85947.1 - 0.00075 19.8 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GBG85947.1 - 0.02 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GBG85947.1 - 0.057 13.5 0.1 0.11 12.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit rve PF00665.26 GBG85948.1 - 5.6e-15 55.6 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG85948.1 - 1.5e-13 50.7 0.0 3.3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG85948.1 - 5.2e-07 30.1 0.0 1.1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85948.1 - 0.00045 20.8 0.0 0.00099 19.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG85948.1 - 0.024 14.4 0.7 0.045 13.5 0.7 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG85948.1 - 0.08 13.2 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger RVP PF00077.20 GBG85948.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Rhodanese PF00581.20 GBG85949.1 - 6.1e-06 26.7 0.0 0.041 14.4 0.0 2.9 2 1 0 2 2 2 2 Rhodanese-like domain PNP_UDP_1 PF01048.20 GBG85949.1 - 0.009 15.3 0.4 0.017 14.4 0.4 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily SAP PF02037.27 GBG85949.1 - 0.12 12.1 0.6 0.86 9.4 0.1 2.2 2 0 0 2 2 2 0 SAP domain DIMCO_N PF16844.5 GBG85949.1 - 0.14 12.5 0.3 0.66 10.3 0.0 2.2 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Rhodanese PF00581.20 GBG85950.1 - 6.5e-06 26.6 0.0 0.041 14.4 0.0 2.9 2 1 0 2 2 2 2 Rhodanese-like domain PNP_UDP_1 PF01048.20 GBG85950.1 - 0.0087 15.3 0.4 0.017 14.4 0.4 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily SAP PF02037.27 GBG85950.1 - 0.12 12.1 0.6 0.87 9.4 0.1 2.2 2 0 0 2 2 2 0 SAP domain DIMCO_N PF16844.5 GBG85950.1 - 0.14 12.5 0.3 0.67 10.3 0.0 2.2 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor, N-terminal PEX11 PF05648.14 GBG85951.1 - 4.9e-42 143.9 0.0 5.6e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Myosin_tail_1 PF01576.19 GBG85951.1 - 0.23 9.2 0.1 0.3 8.8 0.1 1.0 1 0 0 1 1 1 0 Myosin tail Presenilin PF01080.17 GBG85952.1 - 0.089 11.5 16.8 0.12 11.1 16.8 1.2 1 0 0 1 1 1 0 Presenilin Na_trans_assoc PF06512.13 GBG85952.1 - 0.11 12.8 17.4 0.17 12.1 17.4 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated SID-1_RNA_chan PF13965.6 GBG85952.1 - 0.17 10.2 3.7 0.21 10.0 3.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 GBG85952.1 - 0.24 10.4 12.7 0.25 10.3 12.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GBP_C PF02841.14 GBG85952.1 - 0.25 10.7 25.5 0.28 10.5 25.5 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain SAGA-Tad1 PF12767.7 GBG85952.1 - 0.38 10.5 10.5 0.41 10.4 10.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Hid1 PF12722.7 GBG85952.1 - 0.38 8.8 11.3 0.39 8.8 11.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 GBG85952.1 - 0.55 8.4 30.6 0.65 8.1 30.6 1.0 1 0 0 1 1 1 0 Nop14-like family LicD PF04991.13 GBG85952.1 - 0.66 10.1 8.1 0.85 9.7 8.1 1.1 1 0 0 1 1 1 0 LicD family Neur_chan_memb PF02932.16 GBG85952.1 - 0.87 9.6 8.2 1 9.4 8.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 GBG85952.1 - 0.99 8.1 13.6 1.2 7.9 13.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Rtf2 PF04641.12 GBG85952.1 - 1 8.7 23.5 1.5 8.1 23.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger XRN_M PF17846.1 GBG85952.1 - 1.2 8.0 12.6 1.4 7.8 12.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Stig1 PF04885.13 GBG85952.1 - 1.2 9.6 7.2 2.5 8.6 7.2 1.5 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 NARP1 PF12569.8 GBG85952.1 - 1.3 7.9 20.9 2 7.3 20.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.12 GBG85952.1 - 1.5 9.0 15.0 1.6 8.9 15.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2201_N PF13203.6 GBG85952.1 - 1.6 8.2 12.7 2 7.9 12.3 1.4 1 1 0 1 1 1 0 Putative metallopeptidase domain Smg8_Smg9 PF10220.9 GBG85952.1 - 2.6 6.2 11.8 2.7 6.2 11.8 1.1 1 0 0 1 1 1 0 Smg8_Smg9 MCM_bind PF09739.9 GBG85952.1 - 3.7 5.9 16.9 4 5.8 16.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Otopetrin PF03189.13 GBG85952.1 - 3.8 6.2 7.1 5.6 5.7 7.1 1.2 1 0 0 1 1 1 0 Otopetrin Zip PF02535.22 GBG85952.1 - 5 6.2 10.9 6.9 5.8 10.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ALMT PF11744.8 GBG85952.1 - 7.6 5.2 13.6 9.4 4.9 13.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF262 PF03235.14 GBG85952.1 - 8.7 6.4 11.6 11 6.2 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 zf-CCHC PF00098.23 GBG85954.1 - 1.1e-08 34.7 3.1 2e-08 33.9 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG85954.1 - 0.006 16.4 0.7 0.011 15.6 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG85954.1 - 0.036 14.0 0.2 0.065 13.2 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Metal_resist PF13801.6 GBG85954.1 - 0.075 13.2 1.2 0.16 12.1 1.2 1.5 1 0 0 1 1 1 0 Heavy-metal resistance zf-CCHC_6 PF15288.6 GBG85954.1 - 0.092 12.6 0.7 0.092 12.6 0.7 1.9 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH PF17917.1 GBG85955.1 - 2.8e-46 156.1 0.0 4.7e-22 78.3 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85955.1 - 5.5e-36 122.6 0.0 1.7e-20 72.9 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85955.1 - 5.4e-14 52.0 1.5 6.1e-14 51.9 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG85955.1 - 2.4e-10 40.7 0.0 6.9e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG85955.1 - 6.1e-05 23.1 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF4913 PF16259.5 GBG85955.1 - 0.29 11.2 4.1 0.23 11.6 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4913) E2F_TDP PF02319.20 GBG85957.1 - 2.4e-42 142.8 0.6 3.3e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 GBG85957.1 - 0.007 16.2 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF659 PF04937.15 GBG85958.1 - 3e-12 46.6 0.0 5.6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cpn60_TCP1 PF00118.24 GBG85959.1 - 8.2e-156 519.5 4.6 9.2e-156 519.3 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HU-CCDC81_euk_2 PF18289.1 GBG85959.1 - 0.11 12.7 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HSF_DNA-bind PF00447.17 GBG85961.1 - 5.3e-31 107.1 1.3 3.5e-30 104.5 1.6 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding CENP-F_leu_zip PF10473.9 GBG85961.1 - 0.036 14.1 0.4 0.089 12.8 0.4 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ets PF00178.22 GBG85961.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Ets-domain Peptidase_M16 PF00675.20 GBG85961.1 - 0.14 12.1 0.1 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Mur_ligase_M PF08245.12 GBG85962.1 - 5.1e-20 72.3 0.0 1.4e-11 44.7 0.0 2.6 2 1 1 3 3 3 2 Mur ligase middle domain Mur_ligase_C PF02875.21 GBG85962.1 - 1.3e-15 57.4 0.1 4.5e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 GBG85962.1 - 3.8e-10 40.0 0.0 3.7e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 Mur ligase family, catalytic domain AF2331-like PF14556.6 GBG85962.1 - 0.025 15.1 0.0 0.067 13.8 0.0 1.7 1 0 0 1 1 1 0 AF2331-like Methyltransf_24 PF13578.6 GBG85962.1 - 0.025 15.6 0.0 36 5.4 0.0 3.7 3 2 0 3 3 3 0 Methyltransferase domain RT_RNaseH_2 PF17919.1 GBG85963.1 - 9.3e-33 112.3 0.0 2.7e-32 110.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG85963.1 - 4.9e-32 111.2 0.1 9.5e-32 110.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85963.1 - 1.7e-26 92.6 0.1 3.8e-26 91.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG85963.1 - 6.9e-18 64.5 0.6 2e-17 63.0 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG85963.1 - 1.7e-06 28.5 0.0 3.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG85963.1 - 0.0001 22.9 0.0 0.00023 21.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG85963.1 - 0.00015 22.0 0.0 0.00057 20.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG85963.1 - 0.0008 19.6 0.3 0.0036 17.5 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger DUF1758 PF05585.12 GBG85963.1 - 0.014 15.2 0.0 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG85963.1 - 0.03 14.1 0.0 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF1564 PF07600.11 GBG85963.1 - 0.061 13.0 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG85964.1 - 9.3e-25 87.4 0.1 1.4e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85964.1 - 4.3e-19 68.8 0.0 9.8e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85964.1 - 2.3e-15 56.5 0.0 5.6e-12 45.6 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Cwf_Cwc_15 PF04889.12 GBG85964.1 - 1.4 8.6 9.0 2.1 8.0 9.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG85964.1 - 2.1 7.7 12.8 3 7.2 12.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG85964.1 - 5.8 5.0 13.0 7.9 4.6 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG85965.1 - 8e-28 97.5 0.2 1e-15 57.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG85965.1 - 3.1e-20 72.4 0.0 6.4e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG85965.1 - 6.8e-15 54.9 0.0 7.7e-12 45.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Lactamase_B_2 PF12706.7 GBG85965.1 - 0.0066 16.0 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Nop14 PF04147.12 GBG85965.1 - 3.6 5.7 5.7 5 5.2 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family Reticulon PF02453.17 GBG85966.1 - 3.9e-20 72.4 10.8 5.3e-20 72.0 10.8 1.1 1 0 0 1 1 1 1 Reticulon DUF4633 PF15464.6 GBG85966.1 - 0.0076 16.4 0.4 0.013 15.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4633) MgtE PF01769.16 GBG85966.1 - 4 7.8 16.9 1.7 9.0 3.8 2.2 1 1 1 2 2 2 0 Divalent cation transporter RVT_1 PF00078.27 GBG85967.1 - 2.7e-18 66.3 0.5 4.8e-18 65.5 0.5 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Reticulon PF02453.17 GBG85968.1 - 1.7e-29 102.8 10.3 2.4e-29 102.3 10.3 1.2 1 0 0 1 1 1 1 Reticulon DAGK_prokar PF01219.19 GBG85968.1 - 0.18 11.7 2.8 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase CBFD_NFYB_HMF PF00808.23 GBG85969.1 - 1.5e-18 66.8 0.3 2.4e-18 66.1 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RVT_1 PF00078.27 GBG85970.1 - 5.8e-15 55.4 0.1 8.8e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG85970.1 - 1.2e-12 47.7 0.0 2.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG85970.1 - 0.3 10.5 18.4 0.38 10.1 18.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG85970.1 - 0.48 9.7 22.2 0.66 9.3 22.2 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG85970.1 - 1.2 7.2 18.8 1.6 6.8 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG85970.1 - 2.2 6.5 14.4 3.6 5.8 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GBG85970.1 - 2.8 6.6 4.5 3.7 6.2 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4746 PF15928.5 GBG85970.1 - 3.1 7.2 12.9 5.2 6.4 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DHHC PF01529.20 GBG85971.1 - 1.5e-38 132.0 9.1 1.5e-38 132.0 9.1 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase PAXIP1_C PF15364.6 GBG85972.1 - 0.071 13.4 1.8 0.092 13.1 0.1 1.9 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein CLZ PF16526.5 GBG85972.1 - 0.78 10.1 8.2 2.4 8.6 2.0 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin_2 PF01920.20 GBG85972.1 - 2.6 8.1 12.0 0.14 12.1 0.7 2.6 2 1 0 2 2 2 0 Prefoldin subunit DUF724 PF05266.14 GBG85972.1 - 3.4 7.4 10.3 7.5 6.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TPR_14 PF13428.6 GBG85973.1 - 1.4e-10 41.1 25.6 0.00078 20.1 0.3 8.8 5 4 5 10 10 9 4 Tetratricopeptide repeat NRDE-2 PF08424.10 GBG85973.1 - 7.2e-09 35.2 4.9 0.0031 16.7 0.0 3.9 2 2 1 3 3 3 3 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 GBG85973.1 - 6.2e-06 26.6 4.7 0.16 12.5 0.1 3.8 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG85973.1 - 1.2e-05 25.0 14.0 0.058 13.5 0.9 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG85973.1 - 0.00077 19.7 9.9 0.0042 17.4 0.4 4.1 3 2 1 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 GBG85973.1 - 0.0012 18.9 0.3 0.0012 18.9 0.3 4.5 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_6 PF13174.6 GBG85973.1 - 0.0019 18.7 10.7 1.2 9.9 0.5 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG85973.1 - 0.0026 18.4 0.3 0.0026 18.4 0.3 5.1 4 1 0 4 4 3 2 Tetratricopeptide repeat FAT PF02259.23 GBG85973.1 - 0.0083 15.4 5.1 0.067 12.4 1.4 3.0 2 1 0 2 2 2 1 FAT domain TPR_8 PF13181.6 GBG85973.1 - 0.013 15.6 11.3 0.077 13.2 0.6 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF601 PF04642.12 GBG85973.1 - 0.032 13.8 0.1 0.097 12.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF601 TPR_7 PF13176.6 GBG85973.1 - 0.29 11.3 8.9 1.7 8.9 0.1 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG85973.1 - 4.8 7.2 9.6 3.2 7.7 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG85973.1 - 5.8 7.5 5.6 63 4.3 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIA PF03153.13 GBG85973.1 - 9.7 6.1 20.8 1.4 8.8 16.5 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 GBG85974.1 - 0.033 13.9 11.5 0.036 13.8 11.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Osteopontin PF00865.18 GBG85974.1 - 0.21 11.1 17.8 0.24 10.9 17.8 1.0 1 0 0 1 1 1 0 Osteopontin DNA_pol_phi PF04931.13 GBG85974.1 - 0.27 9.3 19.9 0.3 9.2 19.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi eIF-3c_N PF05470.12 GBG85974.1 - 0.28 9.4 1.6 0.29 9.4 1.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 GBG85974.1 - 0.59 8.3 11.7 0.63 8.2 11.7 1.0 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 GBG85974.1 - 0.64 9.7 3.4 0.72 9.5 3.4 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SDA1 PF05285.12 GBG85974.1 - 1.3 8.4 12.6 1.3 8.3 12.6 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GBG85974.1 - 1.9 7.5 19.2 2.1 7.4 19.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 GBG85974.1 - 2 6.6 8.5 2.2 6.5 8.5 1.0 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 GBG85974.1 - 4.2 6.9 8.6 4.3 6.8 8.6 1.1 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 GBG85974.1 - 9.2 5.5 12.5 9.6 5.4 12.5 1.1 1 0 0 1 1 1 0 BUD22 RVT_1 PF00078.27 GBG85975.1 - 9.9e-31 107.0 0.5 2.4e-30 105.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG85975.1 - 0.00031 20.9 0.2 0.0056 16.9 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG85975.1 - 0.0083 15.9 1.0 0.0083 15.9 1.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) APG17 PF04108.12 GBG85975.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 Lipase_3 PF01764.25 GBG85976.1 - 3e-14 53.1 0.0 5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF1631 PF07793.11 GBG85976.1 - 4.3 5.6 5.4 18 3.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) DUF659 PF04937.15 GBG85978.1 - 1.9e-38 131.7 0.0 3.5e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG85978.1 - 0.031 14.0 0.1 0.066 13.0 0.1 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region bZIP_1 PF00170.21 GBG85980.1 - 2.8e-09 36.9 2.7 5.9e-09 35.9 2.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GBG85980.1 - 3e-05 24.0 4.4 3e-05 24.0 4.4 2.5 3 0 0 3 3 3 1 Basic region leucine zipper DDHD PF02862.17 GBG85980.1 - 0.069 13.3 0.9 13 5.8 2.5 2.5 2 0 0 2 2 2 0 DDHD domain Roughex PF06020.11 GBG85980.1 - 0.13 11.3 8.2 0.28 10.3 8.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein SlyX PF04102.12 GBG85980.1 - 0.29 11.8 0.0 0.29 11.8 0.0 2.6 2 0 0 2 2 2 0 SlyX DUF4407 PF14362.6 GBG85980.1 - 5.1 6.3 11.6 17 4.6 11.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Apt1 PF10351.9 GBG85980.1 - 8.6 5.1 6.6 1.3e+02 1.2 7.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain PQ-loop PF04193.14 GBG85981.1 - 2.4e-27 94.5 9.9 7.3e-14 51.3 0.5 2.7 2 1 1 3 3 3 2 PQ loop repeat EII-Sor PF03609.14 GBG85981.1 - 0.0008 18.9 1.8 0.0008 18.9 1.8 1.8 2 0 0 2 2 2 1 PTS system sorbose-specific iic component MtN3_slv PF03083.16 GBG85981.1 - 0.0064 16.5 0.8 0.0064 16.5 0.8 2.2 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Alfin PF12165.8 GBG85982.1 - 1.9e-67 224.8 0.0 2.5e-67 224.4 0.0 1.2 1 0 0 1 1 1 1 Alfin PHD PF00628.29 GBG85982.1 - 7.3e-11 41.8 6.3 1.4e-10 40.9 6.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 GBG85982.1 - 0.0027 18.0 6.0 0.0044 17.3 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain Zf_RING PF16744.5 GBG85982.1 - 0.0065 16.6 3.6 0.019 15.1 3.6 1.8 1 1 0 1 1 1 1 KIAA1045 RING finger zf-HC5HC2H PF13771.6 GBG85982.1 - 0.064 13.5 3.2 0.21 11.9 3.2 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain Ribosomal_60s PF00428.19 GBG85982.1 - 0.26 11.9 2.0 0.46 11.1 2.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-H2C2_2 PF13465.6 GBG85982.1 - 0.31 11.6 3.3 1.8 9.1 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain C1_1 PF00130.22 GBG85982.1 - 0.58 10.1 7.0 0.067 13.1 1.8 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.8 GBG85982.1 - 1.1 9.7 3.9 14 6.1 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PHD_4 PF16866.5 GBG85982.1 - 1.1 9.3 6.6 2.7 8.1 6.6 1.8 1 1 0 1 1 1 0 PHD-finger C1_2 PF03107.16 GBG85982.1 - 1.7 9.0 5.4 2.2 8.7 1.4 2.3 2 0 0 2 2 2 0 C1 domain Alfin PF12165.8 GBG85983.1 - 1.8e-67 224.8 0.0 2.4e-67 224.4 0.0 1.2 1 0 0 1 1 1 1 Alfin PHD PF00628.29 GBG85983.1 - 6.9e-11 41.9 6.3 1.4e-10 40.9 6.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 GBG85983.1 - 0.0027 18.0 6.0 0.0044 17.3 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain Zf_RING PF16744.5 GBG85983.1 - 0.0064 16.6 3.6 0.019 15.1 3.6 1.8 1 1 0 1 1 1 1 KIAA1045 RING finger Ribosomal_60s PF00428.19 GBG85983.1 - 0.11 13.1 2.2 0.19 12.4 2.2 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-HC5HC2H PF13771.6 GBG85983.1 - 0.11 12.7 4.0 0.25 11.6 3.6 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain Sde2_N_Ubi PF13019.6 GBG85983.1 - 0.15 11.9 1.3 0.51 10.1 0.5 1.9 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain zf-H2C2_2 PF13465.6 GBG85983.1 - 0.3 11.6 3.3 1.8 9.1 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain C1_1 PF00130.22 GBG85983.1 - 0.57 10.1 7.0 0.067 13.1 1.8 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.8 GBG85983.1 - 1.1 9.7 3.9 14 6.1 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PHD_4 PF16866.5 GBG85983.1 - 1.1 9.3 6.6 2.8 8.1 6.6 1.8 1 1 0 1 1 1 0 PHD-finger C1_2 PF03107.16 GBG85983.1 - 1.7 9.0 5.4 2.1 8.7 1.4 2.3 2 0 0 2 2 2 0 C1 domain Ribosomal_L4 PF00573.22 GBG85985.1 - 5.2e-63 212.2 0.1 6.4e-63 211.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family GTP_EFTU PF00009.27 GBG85985.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Glycos_transf_2 PF00535.26 GBG85986.1 - 6.5e-15 55.4 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 NUDIX PF00293.28 GBG85986.1 - 2.9e-14 53.2 0.1 5.5e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Glyco_tranf_2_3 PF13641.6 GBG85986.1 - 1.3e-09 38.3 0.0 1e-08 35.4 0.0 2.4 3 1 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GBG85986.1 - 1.8e-07 30.9 0.0 2.6e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Sporozoite_P67 PF05642.11 GBG85986.1 - 0.16 10.1 2.0 0.26 9.3 2.0 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA PF00004.29 GBG85987.1 - 3e-43 147.4 0.1 7.5e-43 146.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG85987.1 - 1e-14 54.0 0.1 2.1e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GBG85987.1 - 8.6e-08 32.0 1.7 1.9e-07 30.9 1.7 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 GBG85987.1 - 1.2e-07 32.0 0.0 5.1e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GBG85987.1 - 1.6e-06 28.6 0.0 4.5e-05 23.9 0.0 3.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GBG85987.1 - 3.3e-06 27.1 0.0 1.1e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG85987.1 - 6.7e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GBG85987.1 - 0.00025 21.3 1.6 0.0078 16.5 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GBG85987.1 - 0.0006 20.0 0.0 0.002 18.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 GBG85987.1 - 0.0012 18.2 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain PhoH PF02562.16 GBG85987.1 - 0.0012 18.3 0.1 0.15 11.5 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_18 PF13238.6 GBG85987.1 - 0.0016 18.9 0.3 0.015 15.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 GBG85987.1 - 0.0028 17.4 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 GBG85987.1 - 0.0066 15.8 0.0 0.02 14.3 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_3 PF07726.11 GBG85987.1 - 0.0068 16.3 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GBG85987.1 - 0.0081 15.6 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GBG85987.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GBG85987.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GBG85987.1 - 0.012 15.3 0.4 0.058 13.1 0.0 2.4 2 1 0 2 2 1 0 AAA domain TsaE PF02367.17 GBG85987.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 GBG85987.1 - 0.018 15.4 0.1 0.67 10.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 GBG85987.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 GBG85987.1 - 0.029 13.5 0.0 0.066 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 GBG85987.1 - 0.032 13.9 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 GBG85987.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 GBG85987.1 - 0.044 14.3 2.2 0.1 13.1 2.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Parvo_NS1 PF01057.17 GBG85987.1 - 0.045 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 GBG85987.1 - 0.046 13.3 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 GBG85987.1 - 0.066 13.0 0.1 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GBG85987.1 - 0.089 13.2 0.8 0.31 11.5 0.0 2.3 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 GBG85987.1 - 0.092 12.7 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 GBG85987.1 - 0.1 13.1 0.1 0.5 10.9 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 GBG85987.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 GBG85987.1 - 0.14 12.5 0.4 0.35 11.1 0.4 1.7 1 0 0 1 1 1 0 Zn-ribbon containing protein Bac_DnaA PF00308.18 GBG85987.1 - 0.17 11.7 1.0 8.1 6.2 0.0 3.0 3 0 0 3 3 3 0 Bacterial dnaA protein RILP PF11461.8 GBG85987.1 - 0.33 11.2 5.3 0.87 9.9 5.3 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein Tropomyosin PF00261.20 GBG85987.1 - 1.2 8.5 7.2 0.57 9.5 2.4 2.2 2 0 0 2 2 2 0 Tropomyosin RPN7 PF10602.9 GBG85988.1 - 1.8e-55 187.4 0.2 3.3e-55 186.5 0.2 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GBG85988.1 - 1.7e-14 54.2 0.0 3.5e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 PCI domain CCDC117 PF15810.5 GBG85988.1 - 0.028 14.7 0.0 0.045 14.1 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 SAPS PF04499.15 GBG85989.1 - 0.17 10.6 2.3 0.17 10.7 2.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 GBG85989.1 - 0.19 11.0 23.1 0.23 10.7 23.1 1.1 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 GBG85989.1 - 0.2 11.7 23.2 0.28 11.3 23.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Isy1 PF06246.12 GBG85989.1 - 0.33 10.5 8.6 0.45 10.0 8.6 1.1 1 0 0 1 1 1 0 Isy1-like splicing family SDA1 PF05285.12 GBG85989.1 - 0.36 10.2 19.5 0.47 9.8 19.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG85989.1 - 0.46 8.6 17.0 0.56 8.4 17.0 1.2 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_4 PF13837.6 GBG85990.1 - 0.0011 19.3 1.4 0.0022 18.3 1.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG85990.1 - 0.0097 16.0 0.9 0.016 15.2 0.9 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG85990.1 - 0.015 15.5 0.2 0.032 14.4 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1298 PF06974.13 GBG85991.1 - 8.1e-35 119.9 0.0 1.3e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 GBG85991.1 - 1.3e-07 31.7 0.2 3.1e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain SOBP PF15279.6 GBG85992.1 - 0.067 13.8 6.0 0.12 12.9 6.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Red1 PF07964.11 GBG85992.1 - 0.17 10.1 20.5 0.21 9.8 20.5 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Merozoite_SPAM PF07133.11 GBG85992.1 - 0.49 10.4 36.1 0.86 9.6 36.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HSP90 PF00183.18 GBG85992.1 - 0.63 8.9 25.8 1.1 8.1 25.8 1.4 1 0 0 1 1 1 0 Hsp90 protein ASC PF00858.24 GBG85992.1 - 0.9 8.4 4.3 1.1 8.1 4.3 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Presenilin PF01080.17 GBG85992.1 - 1.3 7.7 19.5 2.1 7.0 19.5 1.3 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 GBG85992.1 - 1.7 7.4 15.4 2.3 7.0 15.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2052 PF09747.9 GBG85992.1 - 3.2 7.8 32.3 6.4 6.8 32.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Paf1 PF03985.13 GBG85992.1 - 4.1 6.3 29.3 5.9 5.8 29.3 1.2 1 0 0 1 1 1 0 Paf1 Nop53 PF07767.11 GBG85992.1 - 5.1 6.4 41.6 7.9 5.8 41.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SLC12 PF03522.15 GBG85992.1 - 7.7 5.4 19.7 11 4.9 19.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 GBG85992.1 - 8.9 4.5 34.0 14 3.8 34.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG85992.1 - 9.9 5.9 35.4 19 5.0 35.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SMC_hinge PF06470.13 GBG85993.1 - 2.4e-09 37.5 1.3 6.5e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain NPV_P10 PF05531.12 GBG85993.1 - 0.13 12.7 12.7 3.3 8.2 0.1 4.2 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein KASH_CCD PF14662.6 GBG85993.1 - 0.26 11.1 49.1 0.02 14.7 19.0 3.4 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF659 PF04937.15 GBG85994.1 - 2.8e-25 89.0 0.0 8e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG85994.1 - 5.9e-06 26.0 0.4 1.6e-05 24.6 0.4 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2951 PF11166.8 GBG85994.1 - 0.41 10.9 3.0 16 5.8 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF659 PF04937.15 GBG85995.1 - 2.4e-28 98.9 0.0 6.1e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SMC_N PF02463.19 GBG85995.1 - 2.3e-27 95.9 1.0 4e-27 95.1 1.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Dimer_Tnp_hAT PF05699.14 GBG85995.1 - 3.6e-10 39.5 0.3 1.2e-09 37.8 0.3 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AAA_21 PF13304.6 GBG85995.1 - 6.8e-05 22.8 1.0 0.00018 21.5 0.9 1.6 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system TMF_DNA_bd PF12329.8 GBG85995.1 - 0.0006 19.8 9.6 0.0006 19.8 9.6 6.3 3 2 4 7 7 7 1 TATA element modulatory factor 1 DNA binding ABC_tran PF00005.27 GBG85995.1 - 0.011 16.2 1.6 0.011 16.2 1.6 3.3 2 1 0 3 3 3 0 ABC transporter Kelch_4 PF13418.6 GBG85996.1 - 3.6e-42 142.1 0.0 2.2e-08 34.0 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG85996.1 - 4.8e-37 125.4 0.8 7.1e-06 25.9 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GBG85996.1 - 1.5e-33 114.0 0.3 2.2e-07 30.9 0.0 6.0 4 2 2 6 6 6 5 Kelch motif Kelch_3 PF13415.6 GBG85996.1 - 4e-33 113.1 2.6 1.3e-09 38.1 0.0 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.6 GBG85996.1 - 5e-25 87.4 3.4 5e-25 87.4 3.4 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.15 GBG85996.1 - 1.4e-19 69.3 5.5 0.00033 20.5 0.1 6.4 6 1 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GBG85996.1 - 6.6e-19 67.2 7.5 0.0013 18.2 0.0 7.4 7 2 0 7 7 7 4 Kelch motif Myc_N PF01056.18 GBG85996.1 - 0.0089 16.0 8.1 0.0089 16.0 8.1 3.2 3 0 0 3 3 3 1 Myc amino-terminal region XRN_N PF03159.18 GBG85996.1 - 0.18 11.2 8.2 4.4 6.6 7.3 2.3 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus SMN PF06003.12 GBG85997.1 - 2.3e-07 30.3 0.9 4.3e-07 29.5 0.5 1.7 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 GBG85997.1 - 0.00016 21.6 0.0 0.00078 19.5 0.0 2.0 2 1 1 3 3 3 1 Tudor domain Med9 PF07544.13 GBG85997.1 - 0.055 13.6 2.3 0.1 12.7 1.3 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2067 PF09840.9 GBG85997.1 - 0.058 13.0 0.3 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) SH3_3 PF08239.11 GBG85997.1 - 0.096 13.0 0.5 0.26 11.6 0.2 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain NAM PF02365.15 GBG85997.1 - 0.13 13.2 0.3 0.23 12.4 0.3 1.4 1 0 0 1 1 1 0 No apical meristem (NAM) protein DIRP PF06584.13 GBG85997.1 - 0.87 9.8 4.4 41 4.4 0.0 3.1 4 0 0 4 4 4 0 DIRP DUF572 PF04502.13 GBG85997.1 - 6.1 6.4 10.1 0.4 10.3 4.8 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) GNT-I PF03071.15 GBG85998.1 - 8.8e-145 482.8 0.0 1.1e-144 482.4 0.0 1.1 1 0 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 GBG85998.1 - 0.00022 21.2 0.0 0.00075 19.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GBG85998.1 - 0.0039 17.0 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 MGAT2 PF05060.14 GBG85998.1 - 0.015 14.4 0.0 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) Glyco_hydro_71 PF03659.14 GBG85998.1 - 0.027 13.3 0.1 0.047 12.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Lipase_GDSL_2 PF13472.6 GBG86000.1 - 1.7e-30 106.7 0.0 3.3e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GBG86000.1 - 9e-20 71.5 0.0 1.4e-19 70.9 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AlaDh_PNT_N PF05222.15 GBG86000.1 - 0.18 12.1 0.0 0.28 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain Glyco_transf_34 PF05637.12 GBG86001.1 - 1.3e-36 126.6 0.0 6.9e-36 124.2 0.0 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family SKA1 PF07160.12 GBG86002.1 - 1.3e-06 28.5 0.1 0.00018 21.5 0.0 2.3 2 0 0 2 2 2 2 Spindle and kinetochore-associated protein 1 DP PF08781.10 GBG86004.1 - 2.3e-28 98.8 0.0 2.3e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 Transcription factor DP E2F_TDP PF02319.20 GBG86004.1 - 4.4e-25 87.5 0.0 1e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Macoilin PF09726.9 GBG86004.1 - 1.6 7.2 5.5 2.8 6.4 5.5 1.3 1 0 0 1 1 1 0 Macoilin family UPF0515 PF15135.6 GBG86004.1 - 4 6.7 10.6 3.9 6.8 3.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Pentapeptide PF00805.22 GBG86005.1 - 0.00018 21.1 1.0 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 GBG86005.1 - 0.075 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 GBG86005.1 - 0.095 12.9 0.3 0.45 10.7 0.0 2.3 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) DUF2946 PF11162.8 GBG86005.1 - 0.57 10.9 9.2 0.059 14.0 3.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2946) CDC45 PF02724.14 GBG86007.1 - 2.8 6.1 11.0 4.3 5.5 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG86008.1 - 4.6e-27 94.0 0.0 9.1e-15 54.5 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86008.1 - 1.9e-26 92.4 0.0 5.1e-26 91.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86008.1 - 1.2e-18 67.5 0.4 3.2e-07 30.1 0.1 4.2 2 2 2 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86008.1 - 1.2e-08 34.9 0.0 3.7e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Integrase_H2C2 PF17921.1 GBG86009.1 - 8.7e-13 48.2 0.3 1.4e-11 44.4 0.0 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG86009.1 - 4.4e-08 33.3 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Uds1 PF15456.6 GBG86009.1 - 0.11 12.6 2.3 0.98 9.6 1.5 2.4 2 0 0 2 2 2 0 Up-regulated During Septation RT_RNaseH_2 PF17919.1 GBG86010.1 - 2.8e-31 107.5 0.0 4.9e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86010.1 - 8.5e-30 103.1 0.1 1.6e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86010.1 - 3.9e-16 59.3 0.1 9.4e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86010.1 - 1.6e-15 56.9 0.6 3.8e-15 55.7 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG86010.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG86011.1 - 4.4e-33 114.7 0.1 7.8e-33 113.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86011.1 - 2.5e-31 107.7 0.1 9.8e-31 105.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86011.1 - 1.1e-24 86.7 0.0 2.3e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG86011.1 - 8.4e-06 26.3 0.0 3e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86011.1 - 0.0015 19.1 0.0 0.0065 17.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG86011.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG86011.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) NIR_SIR PF01077.22 GBG86011.1 - 0.17 11.4 0.3 0.41 10.1 0.3 1.6 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Retrotrans_gag PF03732.17 GBG86011.1 - 0.23 11.8 0.8 0.58 10.5 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG86012.1 - 1.4e-31 108.5 0.0 1.2e-30 105.5 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86012.1 - 4.5e-29 100.8 0.9 7.1e-28 97.0 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86012.1 - 3e-10 40.0 0.0 8.4e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG86013.1 - 1.4e-17 64.0 0.2 2.5e-17 63.2 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86013.1 - 1.1e-10 41.5 0.0 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86013.1 - 7e-06 26.2 0.0 0.00011 22.3 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger HTH_OrfB_IS605 PF12323.8 GBG86013.1 - 0.057 12.9 0.1 0.097 12.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain RT_RNaseH_2 PF17919.1 GBG86014.1 - 7.6e-30 102.9 0.0 1.3e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86014.1 - 2.6e-24 85.5 0.0 5.3e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86014.1 - 2.7e-15 56.2 0.2 2.7e-15 56.2 0.2 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG86014.1 - 7.8e-08 32.5 0.0 2.1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG86015.1 - 1.9e-32 111.3 0.0 5.1e-32 109.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86015.1 - 6.6e-29 100.3 0.0 2.7e-28 98.3 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86015.1 - 2.4e-25 89.3 0.0 4.8e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86015.1 - 4.5e-17 61.9 1.3 1.4e-16 60.3 1.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_4 PF13359.6 GBG86015.1 - 1.4e-08 34.6 0.0 4.5e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 DDE superfamily endonuclease RVP_2 PF08284.11 GBG86015.1 - 1.6e-08 34.4 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86015.1 - 0.0081 16.8 0.0 0.018 15.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86015.1 - 0.043 14.4 0.0 0.097 13.2 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Nha1_C PF08619.10 GBG86015.1 - 0.25 10.5 39.8 0.027 13.7 31.2 2.2 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus RT_RNaseH_2 PF17919.1 GBG86018.1 - 8.2e-31 106.0 0.0 1.7e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86018.1 - 3.3e-30 104.5 0.0 6.1e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86018.1 - 9e-10 38.5 0.0 2.1e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_lysozyme PF00959.19 GBG86018.1 - 0.019 15.4 0.0 0.098 13.1 0.0 2.2 2 0 0 2 2 2 0 Phage lysozyme RVT_1 PF00078.27 GBG86018.1 - 0.064 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG86018.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.7 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase rve PF00665.26 GBG86019.1 - 9e-09 35.6 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG86020.1 - 3.9e-30 103.8 0.1 1e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86020.1 - 6.7e-17 61.7 0.1 2.3e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86020.1 - 0.0031 17.7 0.1 0.021 15.0 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain DUF3327 PF11806.8 GBG86020.1 - 0.068 13.9 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) Retrotrans_gag PF03732.17 GBG86022.1 - 0.00033 20.9 3.1 0.0016 18.6 0.1 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein SlyX PF04102.12 GBG86022.1 - 0.15 12.7 0.4 0.15 12.7 0.4 2.5 3 0 0 3 3 3 0 SlyX RT_RNaseH_2 PF17919.1 GBG86023.1 - 1.3e-31 108.5 0.0 2.3e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86023.1 - 1.2e-28 99.4 0.1 2.4e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86023.1 - 3.3e-27 94.3 0.6 8.7e-18 64.2 0.1 2.5 2 0 0 2 2 2 2 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86023.1 - 7.5e-09 35.7 0.1 0.0015 18.7 0.0 2.5 2 0 0 2 2 2 2 H2C2 zinc finger rve PF00665.26 GBG86023.1 - 0.085 13.0 0.1 1.7 8.8 0.0 2.9 3 0 0 3 3 3 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG86024.1 - 2.3e-44 149.5 0.0 7.3e-23 80.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86024.1 - 3.7e-44 149.3 0.0 1.3e-20 73.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86024.1 - 1.8e-41 142.1 1.0 2.6e-29 102.3 0.1 3.3 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86024.1 - 1.1e-13 51.1 2.3 1.2e-13 50.9 0.4 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86024.1 - 3.7e-05 23.9 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF913 PF06025.12 GBG86024.1 - 6.2 5.7 5.0 11 4.8 5.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Integrase_H2C2 PF17921.1 GBG86025.1 - 5.1e-19 68.1 0.1 1.2e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG86025.1 - 1.8e-11 43.9 0.0 3.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86025.1 - 5.5e-11 42.4 0.1 9.5e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86025.1 - 8.1e-09 35.7 0.0 2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG86025.1 - 0.00021 21.1 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RT_RNaseH PF17917.1 GBG86025.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG86025.1 - 0.024 14.9 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG86025.1 - 0.041 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG86026.1 - 5.3e-60 199.7 0.0 7.1e-34 115.8 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86026.1 - 3e-50 168.9 0.0 1.6e-26 92.6 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86026.1 - 9.2e-31 107.1 0.1 5e-30 104.7 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86026.1 - 1.4e-25 89.8 0.0 2.8e-14 53.3 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 GBG86026.1 - 3.5e-12 46.2 0.3 3.5e-12 46.2 0.3 3.3 4 0 0 4 4 4 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG86026.1 - 5.3e-06 26.2 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG86026.1 - 1.3e-05 25.7 0.0 3.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86026.1 - 3.7e-05 24.3 0.0 8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG86026.1 - 0.0023 17.7 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG86026.1 - 0.009 15.9 0.0 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG86027.1 - 4.3e-32 111.4 0.1 8.2e-32 110.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG86027.1 - 0.00049 20.6 0.4 0.0038 17.8 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86027.1 - 0.12 13.1 0.0 0.42 11.3 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease DUF5095 PF17016.5 GBG86027.1 - 1.3 8.6 5.4 0.82 9.3 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5095) RVP_2 PF08284.11 GBG86028.1 - 3.7e-15 55.9 0.0 3.5e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86028.1 - 3.8e-12 46.7 0.0 0.00023 21.7 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG86028.1 - 4.7e-09 36.7 0.0 0.0032 18.0 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86028.1 - 1e-06 28.5 0.0 0.033 14.0 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease rve PF00665.26 GBG86028.1 - 1.7e-05 25.0 0.0 7.7e-05 22.9 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain ZapB PF06005.12 GBG86028.1 - 0.0094 16.4 0.1 0.0094 16.4 0.1 3.2 3 0 0 3 3 3 1 Cell division protein ZapB Spore_coat_CotO PF14153.6 GBG86028.1 - 2 8.3 6.8 5.1 7.0 6.8 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Trimer_CC PF08954.11 GBG86029.1 - 0.0054 16.3 2.2 0.0054 16.3 2.2 2.4 2 0 0 2 2 2 1 Trimerisation motif zf-C4H2 PF10146.9 GBG86029.1 - 0.022 15.1 8.1 0.033 14.5 8.1 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein PI3K_P85_iSH2 PF16454.5 GBG86029.1 - 0.16 11.5 23.4 0.02 14.5 18.8 1.8 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3584 PF12128.8 GBG86029.1 - 0.2 9.1 18.8 0.26 8.7 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Glyco_transf_41 PF13844.6 GBG86029.1 - 0.62 8.4 6.1 0.97 7.8 6.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 41 DDHD PF02862.17 GBG86029.1 - 0.67 10.1 3.0 1 9.5 3.0 1.4 1 0 0 1 1 1 0 DDHD domain Asp-B-Hydro_N PF05279.11 GBG86029.1 - 1.4 9.0 11.8 2.2 8.3 11.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TolA_bind_tri PF16331.5 GBG86029.1 - 2.5 8.3 20.4 0.54 10.4 15.2 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF572 PF04502.13 GBG86029.1 - 2.7 7.5 13.3 3.9 7.0 13.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RVT_1 PF00078.27 GBG86030.1 - 5.4e-31 107.8 0.1 9.6e-31 107.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86030.1 - 2.2e-21 75.7 0.0 6.6e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86030.1 - 7.5e-20 70.8 0.0 1.7e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86030.1 - 2.6e-14 53.4 0.0 5.7e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG86030.1 - 4.2e-14 52.7 0.2 2.7e-09 37.2 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG86030.1 - 0.00028 21.0 0.0 0.001 19.3 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG86030.1 - 0.012 15.3 0.0 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG86031.1 - 3.3e-32 111.8 0.0 5.7e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86031.1 - 1e-09 38.6 0.0 2.9e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG86031.1 - 1.2e-07 31.6 0.0 2.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86031.1 - 0.00012 22.6 0.0 0.00031 21.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86031.1 - 0.00034 21.1 0.2 0.0012 19.4 0.0 2.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG86031.1 - 0.0034 17.2 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG86031.1 - 0.037 13.8 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG86031.1 - 1.8 8.7 5.0 0.21 11.7 0.4 1.9 2 0 0 2 2 2 0 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG86032.1 - 3.5e-28 97.6 0.1 7.1e-28 96.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86032.1 - 2.2e-25 89.0 0.2 5.1e-25 87.8 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86032.1 - 6.7e-17 61.8 0.0 2e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86032.1 - 1.1e-09 38.2 0.9 3e-09 36.8 0.9 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG86032.1 - 0.075 12.7 0.7 0.3 10.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) gag-asp_proteas PF13975.6 GBG86033.1 - 4.5e-05 23.9 0.0 0.00014 22.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG86033.1 - 0.0021 18.3 0.0 0.005 17.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86033.1 - 0.0057 17.3 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG86033.1 - 0.0062 16.3 0.2 0.015 15.1 0.1 1.6 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG86033.1 - 0.028 14.7 1.0 0.11 12.8 0.1 2.3 2 1 1 3 3 3 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG86034.1 - 2.2e-23 82.2 0.0 4.2e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86034.1 - 7.6e-21 74.4 0.0 2.2e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86034.1 - 3.7e-13 49.4 0.0 1.1e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86034.1 - 2.5e-11 43.8 0.0 6.3e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG86034.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Diphthami_syn_2 PF01902.17 GBG86034.1 - 0.043 13.3 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Diphthamide synthase RT_RNaseH_2 PF17919.1 GBG86035.1 - 1.7e-21 76.1 0.0 6.9e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86035.1 - 2e-20 73.0 0.0 7e-20 71.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86035.1 - 9.5e-11 41.6 0.1 2.5e-10 40.3 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG86035.1 - 0.0034 17.6 1.3 0.054 13.8 0.0 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein CorA PF01544.18 GBG86035.1 - 0.047 13.0 7.9 0.1 11.9 0.7 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Filament PF00038.21 GBG86035.1 - 2.6 7.5 17.1 2.9 7.4 12.9 2.1 2 0 0 2 2 2 0 Intermediate filament protein CHD5 PF04420.14 GBG86037.1 - 0.091 12.6 3.8 0.16 11.8 3.8 1.4 1 0 0 1 1 1 0 CHD5-like protein RVT_1 PF00078.27 GBG86038.1 - 2.9e-35 121.8 0.0 7.2e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86038.1 - 4.5e-32 110.1 0.0 1.5e-31 108.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86038.1 - 4.9e-31 107.1 0.1 1.2e-30 105.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86038.1 - 0.00032 20.7 0.0 0.00081 19.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG86038.1 - 0.041 13.5 0.1 0.041 13.5 0.1 3.4 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4477 PF14780.6 GBG86038.1 - 0.047 13.3 0.5 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) Flot PF15975.5 GBG86038.1 - 7 6.9 15.3 45 4.3 15.3 2.3 1 1 0 1 1 1 0 Flotillin DUF659 PF04937.15 GBG86039.1 - 3.9e-33 114.5 0.1 6e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG86039.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region CHDCT2 PF08074.11 GBG86039.1 - 0.41 10.8 5.0 7 6.8 4.7 2.4 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain GREB1 PF15782.5 GBG86039.1 - 2.2 5.3 10.6 3 4.8 10.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RVT_1 PF00078.27 GBG86040.1 - 4e-28 98.4 0.1 6.8e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86040.1 - 1.9e-20 73.1 0.0 3.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86040.1 - 1.3e-15 57.3 0.5 4.9e-15 55.4 0.1 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG86040.1 - 5.7e-12 45.4 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG86040.1 - 1.9e-11 43.9 0.0 4.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG86040.1 - 0.00014 22.0 0.1 0.00033 20.8 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger BrnA_antitoxin PF14384.6 GBG86040.1 - 0.19 12.2 0.2 69 4.0 0.0 4.4 5 1 0 5 5 5 0 BrnA antitoxin of type II toxin-antitoxin system RT_RNaseH PF17917.1 GBG86041.1 - 2.9e-21 75.7 0.0 5.5e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86041.1 - 2.9e-19 68.9 0.0 5.6e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86041.1 - 7.1e-08 32.2 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG86041.1 - 0.00027 21.5 0.0 0.00053 20.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86041.1 - 0.027 15.1 0.0 0.053 14.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 GBG86042.1 - 3.8e-13 49.7 0.0 1.4e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG86042.1 - 9.3e-06 25.3 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Got1 PF04178.12 GBG86043.1 - 7.1e-31 107.0 14.8 1.1e-30 106.4 14.8 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF639 PF04842.12 GBG86043.1 - 0.41 10.0 3.5 0.21 11.0 0.7 1.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF639) RVP_2 PF08284.11 GBG86044.1 - 5.3e-09 35.9 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86044.1 - 1.7e-07 31.8 0.0 3.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG86044.1 - 7.7e-07 28.8 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG86044.1 - 1.5e-05 25.4 0.0 3.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86044.1 - 0.026 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG86045.1 - 9.3e-29 100.5 0.1 1.4e-28 99.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86045.1 - 6.6e-19 67.8 0.0 1.3e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86045.1 - 2.5e-07 31.0 0.0 4.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Cupin_1 PF00190.22 GBG86046.1 - 4.4e-43 146.5 0.0 2.8e-24 85.5 0.0 3.1 2 1 1 3 3 3 3 Cupin Cupin_2 PF07883.11 GBG86046.1 - 4.5e-05 23.1 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 Cupin domain RVT_1 PF00078.27 GBG86047.1 - 2e-30 105.9 0.3 8e-30 104.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86047.1 - 3.8e-22 78.6 0.1 6.7e-22 77.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86047.1 - 1.1e-21 76.7 0.0 2.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86047.1 - 6.8e-17 61.3 0.1 2.5e-16 59.5 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG86047.1 - 1e-06 28.5 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86047.1 - 2.9e-06 27.8 0.0 5.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86047.1 - 0.00018 22.0 0.0 0.00031 21.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86047.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Cupin_1 PF00190.22 GBG86048.1 - 8.2e-46 155.3 0.0 1.7e-27 95.9 0.0 3.0 2 1 1 3 3 3 2 Cupin Cupin_2 PF07883.11 GBG86048.1 - 6.7e-07 28.9 0.1 0.038 13.7 0.0 2.7 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 GBG86048.1 - 0.0021 17.7 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) RVT_1 PF00078.27 GBG86049.1 - 4.8e-29 101.4 0.0 7.5e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86049.1 - 1.8e-16 60.0 0.0 7.8e-16 57.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86049.1 - 2.3e-16 59.6 0.7 9.5e-16 57.7 0.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG86049.1 - 6.7e-11 41.9 0.0 1.5e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG86049.1 - 2.7e-10 40.4 0.1 1.1e-09 38.5 0.1 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG86049.1 - 4e-05 23.9 0.1 0.0023 18.2 0.0 2.6 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG86049.1 - 5.2e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG86049.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Cupin_1 PF00190.22 GBG86050.1 - 7.2e-90 298.4 0.0 8.1e-27 93.7 0.0 5.9 4 2 1 5 5 5 4 Cupin Cupin_2 PF07883.11 GBG86050.1 - 1.3e-13 50.4 0.1 0.076 12.7 0.0 4.5 4 0 0 4 4 4 4 Cupin domain Cupin_3 PF05899.12 GBG86050.1 - 1.5e-07 31.0 0.1 4.3 7.1 0.0 4.6 4 0 0 4 4 4 3 Protein of unknown function (DUF861) CENP-C_C PF11699.8 GBG86050.1 - 1.5e-05 25.1 0.0 0.5 10.6 0.0 4.3 4 0 0 4 4 4 2 Mif2/CENP-C like Glyco_hydro_36N PF16875.5 GBG86050.1 - 0.0083 15.7 0.2 3.4 7.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 36 N-terminal domain Rotamase PF00639.21 GBG86050.1 - 0.012 16.5 0.0 9.6 7.2 0.0 3.4 3 0 0 3 3 3 0 PPIC-type PPIASE domain DUF2024 PF09630.10 GBG86050.1 - 0.022 14.6 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) AraC_binding PF02311.19 GBG86050.1 - 0.093 12.6 0.0 24 4.8 0.0 2.9 2 0 0 2 2 2 0 AraC-like ligand binding domain RACo_linker PF17650.1 GBG86050.1 - 0.16 11.8 0.0 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 RACo linker region tRNA_bind_4 PF18490.1 GBG86050.1 - 0.16 11.7 0.0 20 4.9 0.0 2.2 2 0 0 2 2 2 0 tRNA-binding domain SopA_C PF13979.6 GBG86050.1 - 1.6 8.4 5.1 4.4 7.0 0.2 2.4 2 0 0 2 2 2 0 SopA-like catalytic domain Cupin_1 PF00190.22 GBG86051.1 - 1.2e-29 102.9 0.0 7.1e-28 97.1 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GBG86051.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Cupin_1 PF00190.22 GBG86052.1 - 9.5e-47 158.4 0.0 6e-28 97.3 0.0 3.1 2 1 1 3 3 3 2 Cupin Cupin_2 PF07883.11 GBG86052.1 - 1.1e-05 25.1 0.1 0.028 14.1 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 GBG86052.1 - 0.0085 15.8 0.0 2.3 8.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 GBG86052.1 - 0.031 14.5 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Mif2/CENP-C like PLD_C PF12357.8 GBG86053.1 - 2.9e-26 91.2 0.0 6.4e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.22 GBG86053.1 - 2.1e-11 43.5 0.8 3.3e-05 23.9 0.0 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG86053.1 - 1.7e-06 28.0 0.0 2.3e-05 24.3 0.0 2.6 2 1 0 2 2 2 1 PLD-like domain Pyridoxal_deC PF00282.19 GBG86055.1 - 4.8e-21 74.9 0.0 9.2e-14 50.9 0.0 3.1 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GBG86055.1 - 0.0015 17.5 0.0 0.0031 16.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Ribosomal_60s PF00428.19 GBG86055.1 - 0.034 14.7 2.3 0.034 14.7 2.3 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein GOLD_2 PF13897.6 GBG86055.1 - 0.04 14.4 0.2 0.1 13.1 0.2 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking MAM33 PF02330.16 GBG86055.1 - 0.15 12.0 4.6 0.28 11.1 4.6 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein CPSF100_C PF13299.6 GBG86055.1 - 0.15 12.2 1.0 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3408 PF11888.8 GBG86055.1 - 0.23 11.6 5.3 0.24 11.5 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) FAM176 PF14851.6 GBG86055.1 - 1.2 8.8 6.6 0.12 12.0 1.6 1.8 2 0 0 2 2 2 0 FAM176 family Aminoglyc_resit PF10706.9 GBG86057.1 - 3.1e-05 23.8 0.0 7.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Aminoglycoside-2''-adenylyltransferase Cupin_1 PF00190.22 GBG86058.1 - 6.1e-45 152.5 0.0 1.1e-26 93.3 0.0 3.1 2 1 1 3 3 3 2 Cupin Cupin_2 PF07883.11 GBG86058.1 - 2.7e-07 30.2 0.1 0.0062 16.2 0.1 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 GBG86058.1 - 0.0009 18.9 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 GBG86058.1 - 0.0099 16.1 0.0 0.58 10.4 0.0 2.5 2 0 0 2 2 2 1 Mif2/CENP-C like PLD_C PF12357.8 GBG86059.1 - 6e-26 90.2 0.1 1.1e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.22 GBG86059.1 - 8.7e-10 38.4 0.8 0.00052 20.1 0.0 2.9 2 1 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG86059.1 - 1.9e-06 27.8 0.1 1.1e-05 25.3 0.0 2.3 2 1 0 2 2 2 1 PLD-like domain COR PF16095.5 GBG86060.1 - 8.9e-13 48.5 0.0 6.5e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 GBG86060.1 - 9.9e-07 29.0 0.0 1.2e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG86060.1 - 0.0011 18.4 3.1 0.014 14.8 0.0 2.8 2 1 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 GBG86060.1 - 0.015 14.9 1.6 0.024 14.2 0.0 2.2 3 0 0 3 3 3 0 Ras family Synaptobrevin PF00957.21 GBG86060.1 - 0.032 14.0 0.0 0.032 14.0 0.0 2.1 2 0 0 2 2 2 0 Synaptobrevin MMR_HSR1 PF01926.23 GBG86060.1 - 0.42 10.7 1.2 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Integrase_H2C2 PF17921.1 GBG86061.1 - 1.6e-08 34.5 0.1 4.6e-08 33.0 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG86061.1 - 3.6e-08 33.9 0.1 3.5e-06 27.5 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86061.1 - 0.00018 21.3 0.1 0.00041 20.2 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG86061.1 - 0.00041 20.9 0.0 0.00092 19.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Snapin_Pallidin PF14712.6 GBG86061.1 - 0.027 14.9 2.5 13 6.3 1.6 2.9 2 0 0 2 2 2 0 Snapin/Pallidin Prominin PF05478.11 GBG86061.1 - 0.27 9.2 1.8 0.43 8.5 1.8 1.2 1 0 0 1 1 1 0 Prominin COMP PF11598.8 GBG86061.1 - 2.2 8.8 4.9 7.1 7.2 4.9 1.9 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein YabA PF06156.13 GBG86061.1 - 3.4 8.4 14.9 5.7 7.6 11.3 3.3 2 1 0 2 2 2 0 Initiation control protein YabA NFACT-R_1 PF05670.13 GBG86062.1 - 1.3e-43 148.1 0.0 1.9e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain AT_hook PF02178.19 GBG86063.1 - 1.2 9.3 5.6 0.9 9.6 3.1 2.2 2 0 0 2 2 2 0 AT hook motif Cupin_1 PF00190.22 GBG86064.1 - 8e-42 142.4 0.0 3.2e-25 88.5 0.0 2.8 2 1 1 3 3 3 2 Cupin Cupin_2 PF07883.11 GBG86064.1 - 1.1e-06 28.2 0.1 0.021 14.5 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 GBG86064.1 - 0.0026 17.4 0.0 1.6 8.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.22 GBG86067.1 - 2.2e-39 134.5 0.0 2e-24 85.9 0.0 2.7 2 1 1 3 3 3 2 Cupin Cupin_2 PF07883.11 GBG86067.1 - 8.3e-06 25.4 0.1 0.017 14.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 GBG86067.1 - 0.003 17.2 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) THOC2_N PF16134.5 GBG86069.1 - 2.9 6.4 6.4 4.3 5.9 6.4 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus PI3K_1B_p101 PF10486.9 GBG86069.1 - 3.5 5.3 4.6 5.5 4.6 4.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DnaJ PF00226.31 GBG86070.1 - 2.3e-24 85.3 0.6 7.1e-24 83.7 0.6 1.9 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 GBG86070.1 - 3.2e-09 36.8 3.7 3.2e-09 36.8 3.7 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GBG86070.1 - 1.5e-07 31.7 2.2 0.0031 17.8 0.6 2.9 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 GBG86070.1 - 5e-07 29.9 7.7 6e-06 26.5 3.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GBG86070.1 - 9.6e-05 22.9 4.3 0.058 14.3 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2256 PF10013.9 GBG86070.1 - 0.019 15.1 0.8 2.5 8.3 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2 PF00096.26 GBG86070.1 - 0.047 14.2 6.3 0.4 11.2 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 GBG86070.1 - 0.35 10.8 3.1 0.39 10.6 0.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 GBG86070.1 - 1.5 8.9 5.4 2 8.5 1.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger RT_RNaseH PF17917.1 GBG86071.1 - 6.1e-23 81.1 0.0 1.1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86071.1 - 6.7e-23 80.6 0.0 1.1e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86071.1 - 4.9e-17 61.8 0.1 1.4e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG86071.1 - 3.6e-11 43.0 0.3 9e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86071.1 - 1.8e-06 28.1 0.1 6.5e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrin_b_cyt PF08725.11 GBG86071.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RT_RNaseH PF17917.1 GBG86074.1 - 8.5e-29 99.9 0.0 3.3e-28 98.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86074.1 - 1.1e-28 99.2 0.0 4.2e-28 97.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86074.1 - 2.5e-09 37.0 0.0 4.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG86074.1 - 0.076 12.6 0.0 0.076 12.6 0.0 3.2 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase WD40 PF00400.32 GBG86075.1 - 2.1e-08 34.7 1.3 7e-05 23.5 0.1 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 GBG86075.1 - 0.003 16.3 0.0 1.8 7.1 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GBG86075.1 - 0.0036 17.6 0.0 0.47 10.8 0.0 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C48 PF02902.19 GBG86076.1 - 4e-23 82.4 0.0 9.2e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RVT_1 PF00078.27 GBG86077.1 - 5.1e-30 104.6 0.0 8.2e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86077.1 - 1.6e-12 47.7 0.0 4.2e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86077.1 - 2.5e-12 46.7 0.4 6e-12 45.5 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain YdjO PF14169.6 GBG86077.1 - 0.032 14.0 0.2 0.063 13.0 0.2 1.4 1 0 0 1 1 1 0 Cold-inducible protein YdjO rve PF00665.26 GBG86082.1 - 4.5e-16 59.1 0.1 9.9e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86082.1 - 2e-14 53.4 0.2 5.1e-14 52.1 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG86082.1 - 7.7e-13 48.7 2.7 1.7e-12 47.5 2.7 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86082.1 - 0.00012 22.0 1.0 0.00025 21.0 1.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG86082.1 - 0.0016 18.3 0.3 0.0078 16.1 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG86082.1 - 0.082 12.6 0.4 0.33 10.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) DUF2862 PF11061.8 GBG86082.1 - 0.12 12.2 0.4 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) RVT_1 PF00078.27 GBG86083.1 - 2.3e-29 102.5 0.2 3.9e-29 101.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86083.1 - 1.1e-19 70.7 0.0 1.9e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86083.1 - 2e-17 63.1 0.0 4.4e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86083.1 - 1.4e-11 44.3 0.1 1.3e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain Integrin_b_cyt PF08725.11 GBG86083.1 - 0.042 13.5 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain CDH1_2_SANT_HL1 PF18375.1 GBG86083.1 - 0.16 12.7 0.1 0.6 10.8 0.0 1.9 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Myb_DNA-bind_4 PF13837.6 GBG86084.1 - 1.3e-07 31.9 5.4 1.8e-07 31.4 1.7 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Ribonuc_2-5A PF06479.12 GBG86084.1 - 0.033 14.3 0.6 0.24 11.6 0.6 2.2 1 1 0 1 1 1 0 Ribonuclease 2-5A MADF_DNA_bdg PF10545.9 GBG86084.1 - 0.086 13.2 3.2 0.17 12.2 0.6 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVT_1 PF00078.27 GBG86085.1 - 3.4e-25 88.9 0.0 5.3e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG86085.1 - 1.1e-05 25.3 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86085.1 - 0.005 17.5 0.0 0.0095 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Fascin PF06268.13 GBG86085.1 - 0.041 14.1 0.1 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Fascin domain RT_RNaseH_2 PF17919.1 GBG86086.1 - 7.4e-32 109.4 0.1 1.4e-31 108.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86086.1 - 2.1e-29 101.9 0.1 5e-29 100.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86086.1 - 7.5e-17 61.2 0.0 1.6e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG86087.1 - 0.068 13.3 7.1 0.15 12.2 7.1 1.6 1 0 0 1 1 1 0 Zinc knuckle VGLL4 PF15245.6 GBG86088.1 - 0.32 11.0 3.7 37 4.3 0.0 2.2 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 DUF4407 PF14362.6 GBG86088.1 - 8.3 5.7 8.6 13 5.0 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG86089.1 - 1.5e-30 106.3 0.0 2.4e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86089.1 - 1.9e-27 95.2 0.0 5.8e-27 93.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86089.1 - 5.1e-25 87.8 0.1 1.3e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86089.1 - 6.4e-20 71.0 0.6 1.2e-19 70.1 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86089.1 - 0.074 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG86090.1 - 1.1e-29 102.4 0.0 5e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86090.1 - 1.1e-28 99.6 2.9 1.4e-28 99.3 0.0 2.6 3 1 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86090.1 - 0.00011 21.8 0.1 0.00022 20.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86091.1 - 3.7e-16 59.3 1.0 8.4e-16 58.2 1.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86091.1 - 1.9e-10 40.7 0.3 4e-10 39.6 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86091.1 - 0.00012 22.2 0.0 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86092.1 - 1.9e-17 63.1 0.1 4.5e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG86092.1 - 3.7e-16 59.3 1.0 7.5e-16 58.3 1.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86092.1 - 1.7e-10 40.8 0.3 3.6e-10 39.8 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG86092.1 - 0.00016 21.8 0.0 0.00035 20.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG86093.1 - 0.00034 20.8 0.1 0.00034 20.8 0.1 3.0 4 0 0 4 4 4 1 Retrotransposon gag protein YrbL-PhoP_reg PF10707.9 GBG86093.1 - 0.042 13.4 0.9 0.096 12.2 0.9 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SlyX PF04102.12 GBG86093.1 - 0.052 14.2 0.8 0.052 14.2 0.8 3.8 3 0 0 3 3 3 0 SlyX APG6_N PF17675.1 GBG86093.1 - 0.092 13.3 22.6 1.1 9.9 0.9 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region FAM76 PF16046.5 GBG86093.1 - 0.44 9.8 7.4 0.67 9.3 7.4 1.2 1 0 0 1 1 1 0 FAM76 protein RVT_1 PF00078.27 GBG86095.1 - 1.1e-42 146.1 0.1 1.7e-28 99.7 0.1 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86095.1 - 6.3e-24 83.9 0.0 1.6e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86095.1 - 1.6e-22 79.7 0.0 3.7e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86095.1 - 1.9e-07 31.3 0.0 5.6e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86095.1 - 0.00091 19.7 0.0 0.37 11.4 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86095.1 - 0.0046 17.6 0.0 2.3 8.9 0.0 2.8 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG86095.1 - 0.046 14.0 4.7 0.053 13.8 0.0 3.3 4 0 0 4 4 3 0 Retrotransposon gag protein Chromo PF00385.24 GBG86095.1 - 0.061 13.2 0.8 0.22 11.5 0.1 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG86095.1 - 0.16 11.7 0.1 0.83 9.4 0.0 2.2 3 0 0 3 3 3 0 Retroviral aspartyl protease Use1 PF09753.9 GBG86095.1 - 5 6.8 7.8 7.3 6.2 5.4 2.3 2 0 0 2 2 2 0 Membrane fusion protein Use1 CLZ PF16526.5 GBG86095.1 - 5.2 7.5 5.7 6.8 7.1 0.5 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ICA69 PF04629.14 GBG86096.1 - 0.11 12.8 6.8 0.15 12.4 6.8 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain Med26_M PF15694.5 GBG86096.1 - 9.7 6.2 9.0 1.2 9.2 4.8 1.6 2 0 0 2 2 2 0 Mediator complex subunit 26 middle domain RT_RNaseH_2 PF17919.1 GBG86099.1 - 3.3e-34 116.9 0.0 7.6e-34 115.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86099.1 - 1.5e-29 102.3 0.0 3.4e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86099.1 - 1.1e-12 48.0 0.7 6.3e-12 45.5 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86099.1 - 0.00015 21.9 0.0 0.00081 19.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG86099.1 - 0.089 12.7 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain tRNA-synt_1_2 PF13603.6 GBG86100.1 - 0.003 17.1 0.9 0.0053 16.3 0.5 1.5 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 SLC12 PF03522.15 GBG86100.1 - 1.6 7.7 9.7 2.1 7.3 9.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 GBG86100.1 - 7.3 5.4 10.3 9.4 5.0 10.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RT_RNaseH_2 PF17919.1 GBG86101.1 - 2.5e-22 78.8 0.0 5.6e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86101.1 - 1.5e-21 77.0 0.1 2.5e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG86101.1 - 2.7e-11 43.7 4.2 6.7e-11 42.4 4.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH PF17917.1 GBG86101.1 - 3.9e-11 43.2 0.0 1.6e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG86101.1 - 1.7e-06 27.8 0.0 3.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG86101.1 - 4.5e-05 23.9 0.1 0.00013 22.4 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86101.1 - 0.00012 22.7 0.0 0.00064 20.3 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG86101.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Myb_DNA-binding PF00249.31 GBG86101.1 - 0.03 14.5 1.5 0.13 12.5 1.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG86101.1 - 0.045 14.1 1.9 0.15 12.4 1.9 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SPATA24 PF15175.6 GBG86102.1 - 0.19 11.6 1.1 0.31 10.9 1.1 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Presenilin PF01080.17 GBG86103.1 - 1.5 7.5 6.5 2.1 7.0 6.5 1.1 1 0 0 1 1 1 0 Presenilin zf-CCHC PF00098.23 GBG86104.1 - 0.0067 16.5 0.7 0.013 15.6 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86104.1 - 0.093 12.6 1.1 0.17 11.8 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle VP4_2 PF08935.10 GBG86105.1 - 0.27 11.9 1.4 14 6.4 0.0 3.1 3 0 0 3 3 3 0 Viral protein VP4 subunit DUF3381 PF11861.8 GBG86107.1 - 0.058 13.2 31.0 0.068 13.0 31.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RNA_pol_Rpc4 PF05132.14 GBG86107.1 - 0.57 10.6 12.1 0.78 10.2 12.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 GBG86107.1 - 1.1 7.4 25.6 1.2 7.4 25.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S30 PF01577.16 GBG86107.1 - 1.6 8.3 11.8 1.9 8.0 11.8 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease NOA36 PF06524.12 GBG86107.1 - 2.2 7.5 19.7 2.5 7.3 19.7 1.0 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GBG86107.1 - 2.4 6.3 26.2 2.8 6.1 26.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG86107.1 - 4 6.8 29.5 4.7 6.5 29.5 1.0 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 GBG86107.1 - 5.3 7.0 44.3 6.5 6.7 44.3 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Paf1 PF03985.13 GBG86107.1 - 5.5 5.9 30.4 6.2 5.7 30.4 1.1 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 GBG86107.1 - 8.2 5.1 17.5 8.3 5.1 17.5 1.0 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 GBG86107.1 - 9.9 6.2 28.9 14 5.8 28.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3807 PF12720.7 GBG86107.1 - 10 6.4 22.1 11 6.2 22.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF659 PF04937.15 GBG86108.1 - 1.5e-10 41.1 0.0 2.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG86108.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RR_TM4-6 PF06459.12 GBG86110.1 - 6.2 6.6 26.5 6.8 6.4 26.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 GBG86110.1 - 7.4 4.7 46.1 7.9 4.6 46.1 1.0 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 GBG86110.1 - 7.7 5.2 19.9 7.8 5.2 19.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BUD22 PF09073.10 GBG86110.1 - 8.4 5.6 36.6 8.8 5.5 36.6 1.0 1 0 0 1 1 1 0 BUD22 F-112 PF09645.10 GBG86111.1 - 0.085 13.0 1.3 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 F-112 protein LCD1 PF09798.9 GBG86111.1 - 0.48 8.9 8.5 0.55 8.7 8.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4407 PF14362.6 GBG86111.1 - 4.8 6.4 7.7 6.3 6.1 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF659 PF04937.15 GBG86113.1 - 1.4e-14 54.2 0.0 2.3e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Tiam_CC_Ex PF18385.1 GBG86113.1 - 0.1 13.0 0.0 0.4 11.1 0.0 1.9 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain RT_RNaseH PF17917.1 GBG86114.1 - 2.6e-23 82.3 0.0 1.4e-22 80.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86114.1 - 3.1e-21 75.3 0.0 2.3e-19 69.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Macoilin PF09726.9 GBG86114.1 - 0.037 12.6 1.1 0.069 11.7 1.1 1.3 1 0 0 1 1 1 0 Macoilin family EFTUD2 PF16004.5 GBG86114.1 - 2.7 8.6 6.1 0.55 10.8 1.4 2.3 2 1 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus SurE PF01975.17 GBG86115.1 - 5.5e-40 137.2 0.3 6.1e-40 137.1 0.3 1.0 1 0 0 1 1 1 1 Survival protein SurE SlyX PF04102.12 GBG86116.1 - 8.9 7.0 11.5 20 5.9 4.5 3.6 3 1 0 3 3 3 0 SlyX rve PF00665.26 GBG86117.1 - 7.1e-15 55.2 0.0 1.6e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG86118.1 - 2.5e-23 82.0 0.0 3.9e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86118.1 - 5.8e-21 74.7 0.0 1e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86119.1 - 1.1e-63 211.5 0.0 2.6e-31 107.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86119.1 - 4.7e-63 210.0 4.1 5.9e-30 103.7 0.0 3.6 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86119.1 - 5.3e-31 107.8 0.1 1.1e-30 106.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86119.1 - 1.9e-25 88.7 0.1 2.1e-17 63.0 0.4 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG86119.1 - 3e-12 46.8 0.8 1.2e-11 44.8 0.1 2.4 3 0 0 3 3 3 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86119.1 - 1.7e-05 25.3 0.0 4.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86119.1 - 0.0015 19.1 0.0 0.0032 18.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1564 PF07600.11 GBG86119.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) Asp_protease PF09668.10 GBG86119.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG86119.1 - 0.021 15.1 0.4 0.12 12.6 0.4 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein DUF1758 PF05585.12 GBG86119.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) STI1 PF17830.1 GBG86119.1 - 0.15 12.0 0.1 23 5.0 0.0 2.9 3 0 0 3 3 3 0 STI1 domain RT_RNaseH_2 PF17919.1 GBG86120.1 - 5.6e-29 100.1 0.0 1.7e-28 98.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86120.1 - 3.2e-28 98.1 0.1 1.1e-27 96.4 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86120.1 - 1.8e-11 44.0 0.0 6.1e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG86120.1 - 0.00092 19.4 6.4 0.0049 17.1 0.1 4.4 4 1 0 4 4 4 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG86122.1 - 2.5e-11 43.5 0.0 6.4e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG86122.1 - 0.0031 17.1 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG86122.1 - 1.8 8.4 4.4 0.6 10.0 0.7 2.2 3 0 0 3 3 3 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG86123.1 - 0.0086 16.3 0.4 0.052 13.8 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein G3P_antiterm PF04309.12 GBG86124.1 - 0.35 10.3 4.1 0.43 10.0 4.1 1.0 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator rve PF00665.26 GBG86125.1 - 8.8e-09 35.6 0.0 1.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86125.1 - 0.0066 17.0 0.2 0.035 14.7 0.1 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86125.1 - 0.008 16.8 0.3 0.089 13.4 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG86125.1 - 0.017 15.4 0.6 0.085 13.1 0.3 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 GBG86125.1 - 0.044 14.1 0.1 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease rve_3 PF13683.6 GBG86125.1 - 0.063 13.1 0.0 0.28 11.0 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain 7tm_7 PF08395.12 GBG86125.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Tyr-DNA_phospho PF06087.12 GBG86126.1 - 1.1e-08 34.4 0.5 1.8e-08 33.7 0.5 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase gag-asp_proteas PF13975.6 GBG86126.1 - 0.0033 17.9 0.0 0.01 16.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG86126.1 - 0.068 13.5 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG86126.1 - 0.075 13.3 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein PBS_linker_poly PF00427.21 GBG86126.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Asp_protease PF09668.10 GBG86126.1 - 0.18 11.6 0.1 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG86127.1 - 0.00097 19.7 0.0 0.0025 18.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86127.1 - 0.004 17.8 0.0 0.0087 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG86127.1 - 0.0056 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86127.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease alpha-hel2 PF14456.6 GBG86127.1 - 0.082 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 RT_RNaseH_2 PF17919.1 GBG86128.1 - 2.1e-80 265.1 0.0 1.7e-28 98.6 0.0 3.8 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86128.1 - 2.2e-70 233.6 0.0 9.3e-26 90.2 0.1 4.0 4 0 0 4 4 4 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86128.1 - 1.4e-67 227.5 0.6 1.8e-29 102.8 0.1 3.4 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG86128.1 - 1.5e-06 28.3 1.5 0.079 13.3 0.0 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG86128.1 - 0.082 13.6 0.0 0.24 12.0 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG86128.1 - 0.12 13.0 0.0 0.3 11.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG86129.1 - 1.5e-17 63.4 0.2 4.6e-17 61.9 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86129.1 - 2e-11 44.1 0.0 1.2e-10 41.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG86129.1 - 1.2e-07 31.5 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG86129.1 - 0.00087 19.5 0.3 0.045 14.0 0.0 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein Ntox1 PF15500.6 GBG86129.1 - 0.075 13.4 2.7 0.3 11.5 1.0 2.5 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 DUF2913 PF11140.8 GBG86129.1 - 0.28 10.9 3.7 0.57 9.9 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Snapin_Pallidin PF14712.6 GBG86129.1 - 0.63 10.5 8.2 5.6 7.5 0.1 2.9 2 0 0 2 2 2 0 Snapin/Pallidin rve PF00665.26 GBG86130.1 - 1.4e-06 28.5 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86130.1 - 1.6e-06 28.6 0.0 5.6e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86130.1 - 0.00018 22.1 0.0 0.00058 20.5 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease DUF1564 PF07600.11 GBG86130.1 - 0.0064 16.2 0.1 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG86130.1 - 0.02 15.2 0.2 0.33 11.3 0.0 2.9 2 1 1 3 3 3 0 Retrotransposon gag protein DUF1758 PF05585.12 GBG86130.1 - 0.034 13.9 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG86130.1 - 0.037 13.8 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease YabA PF06156.13 GBG86131.1 - 0.05 14.2 1.0 0.24 12.0 0.0 2.2 2 0 0 2 2 2 0 Initiation control protein YabA SOAR PF16533.5 GBG86131.1 - 0.22 11.5 8.2 1.4 8.9 4.1 2.4 2 0 0 2 2 2 0 STIM1 Orai1-activating region RVT_1 PF00078.27 GBG86132.1 - 7.4e-36 123.7 0.1 1.2e-35 123.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86132.1 - 1.1e-28 99.2 0.0 2.1e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86132.1 - 3.9e-23 81.7 0.0 7.3e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ZapB PF06005.12 GBG86133.1 - 0.016 15.6 0.2 0.016 15.6 0.2 3.7 1 1 1 2 2 2 0 Cell division protein ZapB GAS PF13851.6 GBG86133.1 - 0.034 13.5 26.7 0.025 13.9 3.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 GBG86133.1 - 0.42 11.0 17.1 4 7.8 0.0 4.1 3 1 1 4 4 4 0 Csm1 N-terminal domain rve PF00665.26 GBG86134.1 - 0.00099 19.3 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG86135.1 - 5.9e-26 90.4 0.0 1.1e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86135.1 - 1.3e-24 86.4 0.0 3.1e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86135.1 - 4.4e-09 36.2 0.1 7.4e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Longin PF13774.6 GBG86135.1 - 0.045 13.8 0.5 5.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Regulated-SNARE-like domain RVT_1 PF00078.27 GBG86136.1 - 3.2e-27 95.5 0.4 8.3e-27 94.1 0.1 1.7 1 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86136.1 - 3.7e-11 43.2 0.2 8.8e-11 42.0 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86136.1 - 0.013 15.6 0.0 0.013 15.6 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG86137.1 - 0.0032 17.7 1.7 0.0071 16.6 0.2 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein CENP-K PF11802.8 GBG86137.1 - 0.86 9.1 3.1 1.6 8.3 3.1 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Band_7 PF01145.25 GBG86138.1 - 1.4e-07 31.7 0.0 1.8e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family RT_RNaseH_2 PF17919.1 GBG86139.1 - 8.6e-32 109.1 0.0 1.7e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86139.1 - 1.6e-18 66.9 0.0 4e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86139.1 - 2.5e-13 49.9 0.7 1.4e-12 47.5 0.7 2.3 2 1 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86139.1 - 2.6e-13 50.2 0.0 7.1e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG86139.1 - 6.4e-10 38.9 0.2 1.3e-09 37.9 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG86140.1 - 8.9e-09 35.2 0.0 2.7e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86140.1 - 1.4e-07 32.0 0.0 3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86140.1 - 4.3e-07 30.4 0.0 9.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86140.1 - 9e-05 22.3 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Glucan_synthase PF02364.15 GBG86140.1 - 0.31 9.2 0.0 0.43 8.7 0.0 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component RVT_1 PF00078.27 GBG86141.1 - 8.7e-29 100.6 0.0 1.3e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86141.1 - 2.8e-27 94.7 0.0 6.2e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86141.1 - 4e-23 81.7 0.0 8.5e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86141.1 - 2e-08 34.7 0.0 4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86141.1 - 3.2e-08 34.0 0.0 6.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG86141.1 - 3.2e-06 27.0 0.0 5.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86141.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG86141.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Rz1 PF06085.11 GBG86141.1 - 0.18 11.6 1.6 0.44 10.3 1.6 1.6 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor RT_RNaseH_2 PF17919.1 GBG86142.1 - 3.5e-27 94.4 0.1 1.5e-24 85.9 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86142.1 - 5.4e-25 87.7 0.1 3.7e-24 85.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86142.1 - 1.9e-19 70.1 0.1 9e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86142.1 - 2.7e-19 69.0 0.1 5.3e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86142.1 - 9e-09 35.6 0.0 4.4e-08 33.3 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG86142.1 - 1.3e-07 31.4 0.0 3.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86142.1 - 1.6e-07 31.9 0.0 5.1e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86142.1 - 3.6e-05 24.2 0.1 0.0002 21.8 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG86142.1 - 0.0044 17.0 1.2 0.0044 17.0 1.2 3.0 3 0 0 3 3 3 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG86142.1 - 0.019 15.2 0.1 0.13 12.6 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG86142.1 - 0.034 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG86142.1 - 0.095 12.9 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RepB-RCR_reg PF10723.9 GBG86143.1 - 0.13 12.2 0.6 0.21 11.5 0.1 1.6 2 0 0 2 2 2 0 Replication regulatory protein RepB CdvA PF18822.1 GBG86143.1 - 0.51 10.2 3.8 0.24 11.2 0.5 2.0 2 1 0 2 2 2 0 CdvA-like coiled-coil domain NAM-associated PF14303.6 GBG86143.1 - 0.79 10.4 3.7 0.33 11.7 1.0 1.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain RT_RNaseH_2 PF17919.1 GBG86144.1 - 1.5e-24 85.9 0.0 3.8e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86144.1 - 1.9e-22 79.5 0.0 1e-21 77.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG86144.1 - 0.027 14.7 0.1 0.088 13.1 0.1 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein Rx_N PF18052.1 GBG86144.1 - 0.1 12.8 0.1 15 5.9 0.0 2.8 2 0 0 2 2 2 0 Rx N-terminal domain ATG16 PF08614.11 GBG86144.1 - 1.9 8.7 5.6 0.71 10.1 0.5 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Vir_act_alpha_C PF10400.9 GBG86145.1 - 0.036 14.7 0.2 0.036 14.7 0.2 1.6 2 0 0 2 2 2 0 Virulence activator alpha C-term CDC27 PF09507.10 GBG86146.1 - 0.0001 21.9 1.9 0.00013 21.5 1.9 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-CCHC PF00098.23 GBG86146.1 - 0.00048 20.1 6.5 0.00087 19.3 6.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG86146.1 - 0.22 11.3 1.2 0.56 10.0 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF3141 PF11339.8 GBG86146.1 - 0.23 9.9 0.0 0.23 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3141) KDZ PF18758.1 GBG86146.1 - 1.4 8.5 4.2 2.3 7.8 4.2 1.2 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase MDM10 PF12519.8 GBG86146.1 - 1.8 7.4 3.1 2 7.2 3.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF5401 PF17380.2 GBG86146.1 - 5.9 4.8 23.9 8.3 4.4 23.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) YL1 PF05764.13 GBG86147.1 - 0.25 11.4 4.3 0.26 11.4 3.1 1.6 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 GBG86147.1 - 3 6.0 4.3 4.1 5.6 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG86149.1 - 6.4e-24 83.9 0.0 1.3e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86149.1 - 1.1e-21 77.1 0.0 2.6e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG86149.1 - 0.00017 21.5 2.8 0.00032 20.7 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86149.1 - 1.4 8.8 4.5 2.5 8.0 4.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Amidase PF01425.21 GBG86150.1 - 4.1e-67 227.1 0.1 5.5e-67 226.7 0.1 1.1 1 0 0 1 1 1 1 Amidase Myb_DNA-bind_4 PF13837.6 GBG86151.1 - 1.9e-06 28.2 3.5 3e-06 27.5 2.3 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG86151.1 - 0.007 16.7 0.5 0.11 12.9 0.3 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG86151.1 - 0.0091 16.1 1.0 0.035 14.2 1.0 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG86151.1 - 0.11 12.7 0.0 5.4 7.3 0.2 3.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain RVT_1 PF00078.27 GBG86153.1 - 2.3e-28 99.3 0.0 6e-28 97.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PBP PF01161.20 GBG86153.1 - 2.3e-14 53.8 0.0 7.4e-07 29.6 0.0 2.6 2 0 0 2 2 2 2 Phosphatidylethanolamine-binding protein Retrotrans_gag PF03732.17 GBG86153.1 - 0.0016 18.7 0.0 0.0081 16.4 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein HemX PF04375.14 GBG86153.1 - 0.013 14.8 0.9 0.031 13.6 0.9 1.5 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TolA_bind_tri PF16331.5 GBG86153.1 - 0.022 14.8 3.8 0.052 13.6 3.8 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Mucin PF01456.17 GBG86153.1 - 0.12 12.3 29.6 0.18 11.8 18.8 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF1664 PF07889.12 GBG86153.1 - 0.19 11.7 0.1 0.95 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribonuc_red_sm PF00268.21 GBG86154.1 - 7.3e-115 383.2 0.0 8.6e-115 383.0 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Miga PF10265.9 GBG86156.1 - 0.04 12.9 5.8 0.06 12.3 5.8 1.2 1 0 0 1 1 1 0 Mitoguardin Rrn6 PF10214.9 GBG86156.1 - 0.049 12.1 9.9 0.092 11.2 9.9 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Sec15 PF04091.12 GBG86156.1 - 0.1 12.0 0.8 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Exocyst complex subunit Sec15-like NAM-associated PF14303.6 GBG86156.1 - 4.8 7.9 7.7 14 6.4 7.7 1.7 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Thiolase_N PF00108.23 GBG86157.1 - 1.7e-93 312.7 1.8 2.5e-93 312.2 1.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GBG86157.1 - 2.7e-39 133.6 1.8 1.8e-38 131.0 1.1 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GBG86157.1 - 7.9e-06 25.6 4.2 7.4e-05 22.5 0.6 3.0 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GBG86157.1 - 0.094 12.6 3.2 9 6.2 0.2 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RVT_1 PF00078.27 GBG86158.1 - 6.9e-12 45.4 0.0 5.1e-10 39.2 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gal_Lectin PF02140.18 GBG86159.1 - 0.0028 18.0 1.3 0.0028 18.0 1.3 1.7 1 1 0 1 1 1 1 Galactose binding lectin domain RVP_2 PF08284.11 GBG86162.1 - 0.0078 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG86163.1 - 2.8e-07 30.3 0.0 0.00046 19.8 0.0 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) SpmSyn_N PF17950.1 GBG86163.1 - 0.15 12.3 0.0 0.76 10.0 0.0 2.2 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase N -terminal Fungal_KA1 PF16797.5 GBG86163.1 - 0.6 9.8 5.9 0.77 9.5 0.0 3.2 4 0 0 4 4 4 0 Fungal kinase associated-1 domain Ribonuc_red_sm PF00268.21 GBG86164.1 - 1.1e-113 379.4 0.1 1.3e-113 379.2 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Laminin_G_3 PF13385.6 GBG86165.1 - 9.8e-41 139.4 6.5 3.5e-09 37.0 0.0 8.5 8 0 0 8 8 8 5 Concanavalin A-like lectin/glucanases superfamily Kelch_5 PF13854.6 GBG86165.1 - 8.6e-30 102.2 5.8 2.4e-06 27.4 0.0 6.0 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 GBG86165.1 - 2.2e-25 88.4 9.6 2.1e-05 24.4 0.1 6.2 4 1 1 5 5 5 5 Galactose oxidase, central domain Filamin PF00630.19 GBG86165.1 - 8e-21 74.8 0.0 6.1e-07 30.2 0.0 4.8 4 1 0 4 4 4 2 Filamin/ABP280 repeat Kelch_6 PF13964.6 GBG86165.1 - 1e-17 63.7 6.2 0.0059 16.9 0.1 6.5 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 GBG86165.1 - 5.1e-17 61.7 17.1 9.1e-07 29.0 0.1 8.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GBG86165.1 - 7.2e-11 41.6 10.7 0.00038 20.3 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 GBG86165.1 - 6.8e-10 38.4 14.8 0.0068 16.0 0.1 6.5 6 0 0 6 6 6 3 Kelch motif TIG PF01833.24 GBG86165.1 - 1.9e-06 27.9 0.1 0.011 15.8 0.0 4.4 4 0 0 4 4 4 1 IPT/TIG domain Laminin_G_2 PF02210.24 GBG86165.1 - 0.073 13.7 0.0 29 5.3 0.0 3.6 3 0 0 3 3 3 0 Laminin G domain GETHR PF05671.11 GBG86166.1 - 1.2 8.5 4.5 1.3e+02 2.1 4.5 2.8 1 1 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) LMBR1 PF04791.16 GBG86167.1 - 2.2 7.1 7.2 4.3 6.1 7.2 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-CCHC_2 PF13696.6 GBG86168.1 - 0.39 10.6 2.6 0.8 9.6 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Pectinesterase PF01095.19 GBG86169.1 - 1.5e-75 253.7 0.3 1.9e-75 253.4 0.3 1.1 1 0 0 1 1 1 1 Pectinesterase RVT_1 PF00078.27 GBG86170.1 - 0.085 12.4 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RXT2_N PF08595.11 GBG86172.1 - 4.8 7.2 8.6 19 5.3 6.5 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Pectinesterase PF01095.19 GBG86173.1 - 9.8e-75 251.0 0.2 1.2e-74 250.7 0.2 1.1 1 0 0 1 1 1 1 Pectinesterase Asp_protease_2 PF13650.6 GBG86174.1 - 2.8e-07 31.1 0.0 9.8e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG86174.1 - 3e-06 26.9 0.0 4.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG86174.1 - 4.9e-06 27.0 0.0 1.6e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG86174.1 - 0.015 15.6 0.0 0.043 14.1 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RVP_2 PF08284.11 GBG86174.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease p450 PF00067.22 GBG86175.1 - 1.2e-81 274.8 0.0 2e-81 274.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FtsJ PF01728.19 GBG86176.1 - 1.1e-15 58.3 0.0 6.2e-15 55.7 0.1 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 GBG86176.1 - 1.6e-07 31.9 0.0 4.6e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GBG86176.1 - 0.00021 21.9 0.0 0.00056 20.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG86176.1 - 0.00027 20.8 0.0 0.00074 19.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain SDA1 PF05285.12 GBG86176.1 - 0.0017 17.8 23.0 0.0024 17.4 23.0 1.1 1 0 0 1 1 1 1 SDA1 Methyltransf_24 PF13578.6 GBG86176.1 - 0.0029 18.6 0.0 0.0096 16.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 GBG86176.1 - 0.0042 16.8 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 GBG86176.1 - 0.018 14.8 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 GBG86176.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin DUF501 PF04417.12 GBG86176.1 - 0.13 12.1 4.1 0.41 10.4 4.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF501) CDC45 PF02724.14 GBG86176.1 - 0.13 10.5 22.9 0.82 7.9 21.3 2.0 2 0 0 2 2 2 0 CDC45-like protein MID_MedPIWI PF18296.1 GBG86176.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 MID domain of medPIWI Kei1 PF08552.11 GBG86176.1 - 0.28 11.1 0.2 0.58 10.0 0.1 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.17 GBG86176.1 - 1.6 7.4 13.4 2.3 6.9 13.4 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 GBG86176.1 - 1.7 7.3 12.6 2.4 6.8 12.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ANAPC4_WD40 PF12894.7 GBG86177.1 - 0.00038 20.7 0.0 0.42 10.9 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 GBG86180.1 - 1.6e-13 50.7 5.7 1.6e-13 50.7 5.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 GBG86180.1 - 5.5e-11 42.0 2.8 1.3e-10 40.8 2.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GBG86180.1 - 1.1e-08 34.7 5.1 3e-08 33.4 5.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG86180.1 - 4.2e-08 32.9 4.3 9.7e-08 31.8 4.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG86180.1 - 4.6e-07 29.8 2.1 1.1e-06 28.6 2.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GBG86180.1 - 4.8e-07 30.0 7.6 1.6e-06 28.3 7.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GBG86180.1 - 0.0026 17.7 9.7 0.0057 16.6 9.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GBG86180.1 - 0.0049 16.9 5.3 0.011 15.8 5.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GBG86180.1 - 0.013 15.4 9.7 0.013 15.4 9.7 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG86180.1 - 0.02 14.7 7.4 0.047 13.5 7.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2808 PF10989.8 GBG86180.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Zn_ribbon_17 PF17120.5 GBG86180.1 - 0.56 9.9 6.5 1.3 8.7 6.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 GBG86180.1 - 1.1 9.6 6.2 3.6 8.0 6.2 1.9 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 GBG86180.1 - 5.1 7.0 9.0 11 5.9 9.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1995 PF09353.10 GBG86181.1 - 6.4e-26 91.6 0.0 7.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF502 PF04367.13 GBG86181.1 - 0.5 10.3 4.2 0.84 9.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF502) TadF PF16964.5 GBG86181.1 - 3.4 7.4 8.2 5.4 6.7 8.2 1.2 1 0 0 1 1 1 0 Putative tight adherence pilin protein F DUF659 PF04937.15 GBG86182.1 - 1.1e-34 119.5 0.1 2.6e-34 118.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG86182.1 - 3.7e-16 59.4 0.4 1.9e-14 53.9 0.0 3.2 4 0 0 4 4 4 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86182.1 - 2.9e-14 52.9 0.3 1.4e-13 50.7 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain Dimer_Tnp_hAT PF05699.14 GBG86182.1 - 4.6e-10 39.1 0.1 1.1e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-H2C2 PF09337.10 GBG86182.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger ADK PF00406.22 GBG86183.1 - 3.9e-47 160.1 0.0 6.2e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GBG86183.1 - 4e-26 92.0 0.0 1.8e-25 90.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 GBG86183.1 - 5.4e-07 30.2 0.0 1.1e-06 29.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GBG86183.1 - 3.5e-05 24.0 0.0 0.0034 17.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 GBG86183.1 - 0.00036 20.3 0.7 1.3 8.7 0.0 3.2 1 1 1 2 2 2 1 Thymidylate kinase DUF1995 PF09353.10 GBG86183.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Zeta_toxin PF06414.12 GBG86183.1 - 0.0071 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF5449 PF17528.2 GBG86183.1 - 0.023 14.5 0.1 0.053 13.3 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5449) RT_RNaseH_2 PF17919.1 GBG86184.1 - 0.045 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG86184.1 - 2 7.7 33.3 3.3 7.1 33.3 1.3 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.10 GBG86184.1 - 7 6.9 17.0 12 6.1 17.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YL1 PF05764.13 GBG86185.1 - 0.39 10.8 6.2 0.37 10.9 2.2 2.5 2 0 0 2 2 2 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GBG86185.1 - 0.74 9.5 4.5 0.24 11.1 0.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG86185.1 - 4.5 5.4 4.3 8.4 4.6 4.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4257 PF14074.6 GBG86186.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) Dimer_Tnp_hAT PF05699.14 GBG86187.1 - 0.0002 21.1 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG86189.1 - 4.9e-36 124.3 0.0 7.9e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86189.1 - 3.6e-13 49.4 0.0 1.2e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86189.1 - 0.00025 21.3 0.0 0.00065 20.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SelR PF01641.18 GBG86191.1 - 2.4e-50 169.7 0.1 2.8e-50 169.4 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 GBG86191.1 - 0.004 17.3 0.2 0.0071 16.6 0.2 1.4 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nop14 PF04147.12 GBG86192.1 - 0.078 11.2 5.8 0.083 11.1 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG86192.1 - 2.3 7.6 9.1 2.7 7.4 9.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG86192.1 - 8.7 4.5 7.3 10 4.2 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Retrotrans_gag PF03732.17 GBG86195.1 - 0.057 13.7 0.2 0.057 13.7 0.2 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG86196.1 - 3.4e-17 62.7 0.0 7.5e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86196.1 - 2.1e-14 53.3 0.0 5e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86196.1 - 1.1e-11 44.6 0.0 3.7e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain PALP PF00291.25 GBG86197.1 - 7.3e-67 225.8 1.5 8.8e-67 225.6 1.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3147 PF11345.8 GBG86197.1 - 0.14 12.5 1.3 0.61 10.5 1.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3147) PTPRCAP PF15713.5 GBG86199.1 - 0.14 12.5 6.6 0.39 11.0 6.6 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated GOLD_2 PF13897.6 GBG86199.1 - 0.78 10.2 5.0 1.5 9.3 5.0 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FAM176 PF14851.6 GBG86199.1 - 2.4 7.8 6.2 4.4 7.0 6.2 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 GBG86199.1 - 2.9 7.6 8.3 5.6 6.7 8.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein YqfQ PF14181.6 GBG86199.1 - 6.7 6.9 6.6 15 5.8 6.6 1.5 1 0 0 1 1 1 0 YqfQ-like protein RCC1 PF00415.18 GBG86200.1 - 2.8e-49 165.5 37.7 2.4e-14 53.7 0.0 8.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG86200.1 - 3.1e-33 112.9 50.6 7.1e-09 35.2 1.6 8.5 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 GBG86200.1 - 0.045 13.8 0.2 52 4.0 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Hira PF07569.11 GBG86200.1 - 0.069 12.9 0.1 32 4.1 0.0 3.5 4 0 0 4 4 4 0 TUP1-like enhancer of split RVT_1 PF00078.27 GBG86201.1 - 5.1e-34 117.7 0.0 9.8e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Las1 PF04031.13 GBG86201.1 - 1.3e-10 41.6 0.0 2.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Las1-like Exo_endo_phos PF03372.23 GBG86201.1 - 0.011 15.3 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family CBM_4_9 PF02018.17 GBG86201.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain SAGA-Tad1 PF12767.7 GBG86201.1 - 6.5 6.4 7.2 7.4 6.2 0.5 2.5 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Tcp11 PF05794.13 GBG86202.1 - 4.2e-54 184.3 0.0 4e-53 181.1 0.0 2.1 1 1 0 1 1 1 1 T-complex protein 11 DDHD PF02862.17 GBG86204.1 - 0.29 11.3 1.3 0.33 11.1 1.3 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 GBG86204.1 - 0.52 9.0 3.1 0.63 8.7 3.1 1.2 1 0 0 1 1 1 0 Presenilin DUF4228 PF14009.6 GBG86204.1 - 1.5 9.2 12.2 3.1 8.1 12.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Eapp_C PF10238.9 GBG86204.1 - 2.9 8.0 6.5 5.9 7.0 6.5 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein RPN2_C PF18004.1 GBG86204.1 - 3.9 7.4 20.0 3.3 7.6 17.4 1.9 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sec62 PF03839.16 GBG86204.1 - 6 6.3 8.2 11 5.5 8.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 RVT_1 PF00078.27 GBG86205.1 - 1.6e-26 93.2 0.1 2.8e-26 92.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG86205.1 - 1.9e-06 28.3 0.0 5.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86205.1 - 1.9e-06 28.4 0.0 8.4e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG86205.1 - 0.00016 21.4 0.0 0.00039 20.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86205.1 - 0.00072 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG86205.1 - 0.024 14.7 0.0 0.1 12.7 0.0 2.1 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG86206.1 - 1.1 7.3 12.5 1.5 6.9 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG86208.1 - 5.6e-33 113.0 0.1 1e-32 112.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86208.1 - 3.4e-30 104.4 0.1 6.2e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86208.1 - 5.6e-27 94.7 0.0 1e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86208.1 - 1.1e-17 63.9 0.1 2.7e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG86208.1 - 1.2e-06 29.0 0.0 2.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG86208.1 - 5.8e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86208.1 - 0.00035 21.1 0.0 0.00089 19.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG86208.1 - 0.0025 17.6 0.1 0.007 16.2 0.0 1.7 2 0 0 2 2 2 1 Putative peptidase (DUF1758) rve PF00665.26 GBG86208.1 - 0.011 15.9 0.1 0.041 14.1 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 GBG86208.1 - 0.047 13.9 0.0 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger FAM176 PF14851.6 GBG86209.1 - 0.0058 16.3 0.1 0.0096 15.6 0.1 1.3 1 0 0 1 1 1 1 FAM176 family DUF1754 PF08555.10 GBG86209.1 - 0.025 15.3 9.8 0.025 15.3 9.8 1.5 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF2052 PF09747.9 GBG86209.1 - 0.032 14.4 2.4 0.032 14.4 2.4 1.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF1168 PF06658.12 GBG86209.1 - 0.053 13.3 10.6 0.091 12.6 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CENP-B_dimeris PF09026.10 GBG86209.1 - 0.23 11.9 8.5 0.58 10.6 8.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TT_ORF2 PF02957.15 GBG86209.1 - 0.55 11.2 4.9 0.97 10.4 4.9 1.4 1 0 0 1 1 1 0 TT viral ORF2 WRNPLPNID PF15017.6 GBG86209.1 - 1 10.3 10.0 0.16 12.8 6.2 1.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box RNA_pol_3_Rpc31 PF11705.8 GBG86209.1 - 4.3 7.5 17.9 3.1 8.0 15.5 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 GBG86209.1 - 4.5 7.0 9.5 0.93 9.3 6.3 1.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RPN2_C PF18004.1 GBG86209.1 - 8.4 6.3 9.3 4.7 7.1 7.1 1.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain MutS_V PF00488.21 GBG86210.1 - 1.6e-10 41.3 0.0 2.5e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V DUF659 PF04937.15 GBG86211.1 - 1e-36 126.1 0.0 1.7e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) MutS_V PF00488.21 GBG86212.1 - 1.6e-40 139.2 0.5 2.4e-40 138.6 0.5 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GBG86212.1 - 5e-35 121.5 0.0 1e-34 120.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 GBG86212.1 - 1.2e-24 86.7 0.1 2.5e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 GBG86212.1 - 1.7e-15 57.2 0.1 3.9e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV LBR_tudor PF09465.10 GBG86212.1 - 0.0062 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Agenet PF05641.12 GBG86212.1 - 0.064 13.7 0.6 6.9 7.2 0.2 2.8 2 0 0 2 2 2 0 Agenet domain MutS_II PF05188.17 GBG86212.1 - 0.069 13.4 0.1 0.66 10.3 0.0 2.7 3 0 0 3 3 3 0 MutS domain II ALMT PF11744.8 GBG86213.1 - 9.9e-84 281.8 0.0 1.2e-79 268.4 0.0 2.0 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.6 GBG86213.1 - 3.8e-08 33.5 8.2 3.8e-08 33.5 8.2 1.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 GBG86213.1 - 1.5e-07 30.4 3.1 2.2e-07 29.8 3.1 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family Bax1-I PF01027.20 GBG86213.1 - 0.22 11.3 7.1 0.34 10.7 7.1 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 CwfJ_C_1 PF04677.15 GBG86214.1 - 1.3e-38 131.6 0.1 2e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 GBG86214.1 - 3e-29 101.8 0.0 1.5e-28 99.6 0.0 2.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Macoilin PF09726.9 GBG86214.1 - 2.2 6.8 14.0 3.5 6.1 14.0 1.3 1 0 0 1 1 1 0 Macoilin family ketoacyl-synt PF00109.26 GBG86215.1 - 6e-55 186.6 2.5 1.9e-54 184.9 0.6 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GBG86215.1 - 6.5e-41 139.1 0.3 1.2e-40 138.3 0.3 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GBG86215.1 - 6.9e-06 25.6 0.6 0.0001 21.7 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF1640 PF07798.11 GBG86216.1 - 7.3e-58 195.5 9.6 9.5e-58 195.1 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Glyco_hydro_38 PF18438.1 GBG86216.1 - 0.18 11.8 0.3 0.37 10.8 0.3 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 Baculo_PEP_C PF04513.12 GBG86216.1 - 2 8.4 7.1 12 5.9 2.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus S1FA PF04689.13 GBG86217.1 - 9e-26 89.8 1.4 1e-25 89.6 1.4 1.1 1 0 0 1 1 1 1 DNA binding protein S1FA 7TM_GPCR_Srv PF10323.9 GBG86217.1 - 0.016 14.6 0.2 0.02 14.2 0.2 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv HemY_N PF07219.13 GBG86217.1 - 0.045 13.9 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TssO PF17561.2 GBG86217.1 - 0.058 13.5 0.1 0.071 13.2 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF3112 PF11309.8 GBG86217.1 - 0.11 12.0 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Amnionless PF14828.6 GBG86217.1 - 0.15 10.9 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Amnionless zf-C2H2 PF00096.26 GBG86218.1 - 0.024 15.1 0.3 0.064 13.7 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 GBG86218.1 - 0.037 14.0 1.9 0.083 12.8 1.9 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 GBG86218.1 - 0.094 13.6 1.6 0.27 12.2 1.6 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Mpp10 PF04006.12 GBG86220.1 - 0.54 8.6 54.5 0.58 8.5 54.5 1.0 1 0 0 1 1 1 0 Mpp10 protein NPV_P10 PF05531.12 GBG86222.1 - 0.15 12.5 6.4 8.1 7.0 6.4 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 GBG86222.1 - 0.23 11.9 1.2 6.8 7.2 0.2 3.0 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 GBG86222.1 - 0.93 9.6 0.0 0.93 9.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Asp-B-Hydro_N PF05279.11 GBG86222.1 - 3.5 7.6 12.5 6.1 6.8 12.5 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1664 PF07889.12 GBG86222.1 - 5 7.2 10.7 0.42 10.7 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 GBG86222.1 - 7.7 6.8 24.3 0.11 12.7 0.4 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding RVT_1 PF00078.27 GBG86223.1 - 6.4e-34 117.4 0.0 1.4e-33 116.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86223.1 - 1.6e-28 98.6 0.0 4.9e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86223.1 - 1.3e-27 96.1 0.0 4e-27 94.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG86223.1 - 3.3e-06 27.3 3.7 0.0053 17.0 0.0 4.3 4 0 0 4 4 4 2 Retrotransposon gag protein DUF4187 PF13821.6 GBG86223.1 - 0.059 13.2 1.6 0.17 11.7 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) gpUL132 PF11359.8 GBG86223.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 RT_RNaseH PF17917.1 GBG86224.1 - 4e-18 65.6 0.0 1.1e-07 32.1 0.0 2.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86224.1 - 5.1e-18 65.0 0.0 3.9e-16 58.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86224.1 - 2e-10 40.6 0.4 3.2e-10 39.9 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTPRCAP PF15713.5 GBG86224.1 - 0.72 10.1 20.1 1.2 9.4 20.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Glutaredoxin PF00462.24 GBG86225.1 - 1.7e-09 37.8 0.0 4.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 GBG86225.1 - 0.0043 17.2 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein WD40 PF00400.32 GBG86227.1 - 0.0003 21.5 10.8 0.37 11.7 0.1 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat FAD_binding_2 PF00890.24 GBG86228.1 - 1.2e-78 265.1 0.5 1.5e-78 264.8 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GBG86228.1 - 2.1e-15 56.8 0.0 3.9e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term gag-asp_proteas PF13975.6 GBG86229.1 - 4.4e-06 27.2 0.0 1.3e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86229.1 - 4.8e-06 26.4 0.4 1.1e-05 25.2 0.2 1.7 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG86229.1 - 0.00038 21.1 0.0 0.0013 19.3 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG86229.1 - 0.033 14.5 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4118 PF13493.6 GBG86229.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DUF4407 PF14362.6 GBG86230.1 - 1.1e-05 25.0 2.9 1.1e-05 25.0 2.9 2.6 1 1 2 3 3 3 2 Domain of unknown function (DUF4407) DUF1043 PF06295.12 GBG86230.1 - 0.00082 19.4 3.9 0.043 13.8 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1043) DUF2046 PF09755.9 GBG86230.1 - 0.0059 15.9 5.0 0.024 13.9 4.8 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF4996 PF16387.5 GBG86230.1 - 0.0075 16.7 0.0 0.025 15.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function InvH PF04741.12 GBG86230.1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Lectin_N PF03954.14 GBG86230.1 - 0.22 11.3 2.9 0.9 9.3 0.0 3.1 3 2 0 3 3 3 0 Hepatic lectin, N-terminal domain COMPASS-Shg1 PF05205.12 GBG86230.1 - 0.28 11.9 3.0 0.54 11.0 0.7 2.6 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Spc7 PF08317.11 GBG86230.1 - 2.4 6.9 13.2 2.5 6.9 5.7 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 GBG86230.1 - 3 7.9 9.9 0.068 13.3 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 GBG86230.1 - 4.4 7.7 8.0 2.6 8.4 0.1 3.4 3 1 1 4 4 4 0 Csm1 N-terminal domain DUF4618 PF15397.6 GBG86230.1 - 5 6.5 10.5 2.8 7.3 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Kinesin PF00225.23 GBG86232.1 - 2.8e-89 299.3 1.4 4.7e-89 298.6 1.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG86232.1 - 2e-27 96.0 0.1 5.5e-27 94.5 0.1 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 GBG86232.1 - 0.14 11.7 0.1 0.33 10.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3209 PF11483.8 GBG86232.1 - 0.16 12.4 7.4 0.26 11.8 4.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3209) DUF3782 PF12644.7 GBG86232.1 - 0.71 10.1 0.0 0.71 10.1 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3782) YchF-GTPase_C PF06071.13 GBG86233.1 - 3.3e-40 136.1 0.4 9.8e-40 134.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GBG86233.1 - 5.3e-23 81.3 0.0 1.2e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG86233.1 - 2.7e-07 30.3 1.4 8.2e-07 28.7 0.1 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 GBG86233.1 - 0.081 11.9 0.8 0.24 10.3 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 GBG86233.1 - 0.14 12.7 0.2 0.38 11.3 0.2 1.8 1 1 0 1 1 1 0 ABC transporter Fcf2 PF08698.11 GBG86234.1 - 7.9e-38 128.8 0.2 2.4e-37 127.2 0.2 1.9 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Nop14 PF04147.12 GBG86234.1 - 0.028 12.7 30.9 0.041 12.1 30.9 1.3 1 0 0 1 1 1 0 Nop14-like family Pes-10 PF07149.11 GBG86234.1 - 1 8.4 26.4 1.6 7.7 26.4 1.2 1 0 0 1 1 1 0 Pes-10 DUF913 PF06025.12 GBG86234.1 - 5.1 6.0 6.9 8.3 5.3 6.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAST_1 PF06743.15 GBG86235.1 - 3.3e-17 62.2 0.1 0.00054 19.9 0.0 5.4 4 1 1 5 5 5 4 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 GBG86235.1 - 5.7e-14 52.1 0.0 7.8e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 REase_MTES_1575 RAP PF08373.10 GBG86235.1 - 9.5e-11 41.6 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 RAP domain AbiTii PF18864.1 GBG86235.1 - 0.0018 18.4 0.0 0.44 10.7 0.0 2.6 2 1 1 3 3 3 2 AbiTii DUF559 PF04480.12 GBG86235.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF559) DUF4745 PF15923.5 GBG86235.1 - 0.13 12.3 0.0 15 5.5 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4745) FAST_1 PF06743.15 GBG86236.1 - 2.4e-17 62.6 0.1 0.00051 19.9 0.0 5.4 4 1 1 5 5 5 4 FAST kinase-like protein, subdomain 1 RAP PF08373.10 GBG86236.1 - 9.2e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 GBG86236.1 - 3.1e-09 36.9 0.0 7.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 GBG86236.1 - 0.0084 16.0 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF559) Cyclin_N PF00134.23 GBG86238.1 - 3.7e-13 49.3 0.3 8.7e-13 48.1 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 GBG86238.1 - 0.0012 18.8 0.7 0.023 14.7 0.1 2.6 2 0 0 2 2 2 1 Transcription factor TFIIB repeat VIR_N PF15912.5 GBG86238.1 - 2.5 7.6 8.1 4.5 6.8 8.1 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 GBG86238.1 - 9.3 6.0 8.4 14 5.4 8.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Trypan_PARP PF05887.11 GBG86238.1 - 9.4 6.2 7.6 18 5.3 7.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-C2H2_10 PF16588.5 GBG86239.1 - 0.13 12.0 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger TFIID_NTD2 PF04494.15 GBG86240.1 - 7.1e-47 158.9 0.1 9.2e-47 158.5 0.1 1.1 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain LisH PF08513.11 GBG86240.1 - 0.00028 20.7 0.2 0.00066 19.5 0.2 1.6 1 0 0 1 1 1 1 LisH RVT_1 PF00078.27 GBG86241.1 - 2.8e-27 95.7 0.1 5.4e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_7 PF13499.6 GBG86241.1 - 2.8e-09 37.3 0.0 3.6e-05 24.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG86241.1 - 1.4e-07 30.8 0.8 0.028 14.3 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain Asp_protease_2 PF13650.6 GBG86241.1 - 5.6e-07 30.1 0.0 1.7e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG86241.1 - 6.2e-07 29.3 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG86241.1 - 8.6e-07 29.4 0.0 2.5e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease EF-hand_1 PF00036.32 GBG86241.1 - 0.00016 20.9 0.3 0.039 13.5 0.1 2.8 2 0 0 2 2 2 1 EF hand Asp_protease PF09668.10 GBG86241.1 - 0.00026 20.8 0.0 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG86241.1 - 0.005 17.1 0.8 0.041 14.2 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein EF-hand_5 PF13202.6 GBG86241.1 - 0.0054 16.2 0.2 0.96 9.1 0.0 2.9 2 0 0 2 2 2 1 EF hand Chromo PF00385.24 GBG86241.1 - 0.077 12.9 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Wtap PF17098.5 GBG86241.1 - 0.28 11.1 2.5 0.39 10.6 0.7 2.2 2 0 0 2 2 2 0 WTAP/Mum2p family DDE_Tnp_4 PF13359.6 GBG86242.1 - 5.7e-25 87.8 0.0 7.9e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86242.1 - 1e-08 35.1 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein RVT_1 PF00078.27 GBG86243.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG86244.1 - 8.3e-35 120.3 0.1 2.5e-34 118.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAWADEE PF16719.5 GBG86244.1 - 4.9e-09 36.3 1.4 4.9e-09 36.3 1.4 1.9 2 0 0 2 2 2 1 SAWADEE domain Agenet PF05641.12 GBG86244.1 - 0.0004 20.8 4.5 0.0034 17.8 0.1 3.3 4 0 0 4 4 4 1 Agenet domain Tudor_4 PF18358.1 GBG86244.1 - 0.19 11.3 5.9 0.27 10.9 0.8 2.8 2 1 1 3 3 3 0 Histone methyltransferase Tudor domain Oxidored_q3 PF00499.20 GBG86245.1 - 0.0056 16.4 0.3 0.38 10.5 0.0 3.1 3 1 0 3 3 3 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF5069 PF16798.5 GBG86246.1 - 0.068 13.4 6.0 0.23 11.6 0.5 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5069) TFIIE-A_C PF11521.8 GBG86246.1 - 2.9 8.3 17.4 7.6 6.9 0.9 3.2 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DNA_pack_N PF02500.15 GBG86246.1 - 3 7.6 7.6 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Apis_Csd PF11671.8 GBG86247.1 - 9.5 6.2 13.3 6.7 6.7 0.2 2.2 2 0 0 2 2 2 0 Complementary sex determiner protein PLD_C PF12357.8 GBG86249.1 - 1.2e-25 89.2 0.0 4.4e-25 87.4 0.0 2.0 2 0 0 2 2 2 1 Phospholipase D C terminal C2 PF00168.30 GBG86249.1 - 4.1e-17 62.4 0.0 4e-16 59.2 0.0 2.4 2 0 0 2 2 2 1 C2 domain PLDc PF00614.22 GBG86249.1 - 1.4e-15 56.8 0.0 3e-06 27.2 0.0 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG86249.1 - 9.3e-10 38.5 0.0 6.2e-07 29.4 0.1 3.1 2 1 0 2 2 2 2 PLD-like domain RT_RNaseH_2 PF17919.1 GBG86250.1 - 8.2e-24 83.5 0.0 1.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86250.1 - 9.8e-20 70.8 0.0 1.6e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86250.1 - 9.9e-10 38.3 0.1 2.2e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG86250.1 - 0.032 12.5 8.8 0.041 12.1 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG86250.1 - 0.17 11.3 11.4 0.24 10.8 11.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG86250.1 - 0.34 9.2 9.5 0.45 8.8 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG86250.1 - 9.3 4.7 14.7 14 4.1 14.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2288 PF10052.9 GBG86251.1 - 0.29 11.2 2.2 0.4 10.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) Gpi16 PF04113.14 GBG86251.1 - 0.33 9.4 1.8 0.4 9.1 1.8 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component RT_RNaseH_2 PF17919.1 GBG86254.1 - 4.3e-33 113.3 0.1 1e-32 112.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86254.1 - 7.1e-30 103.4 0.0 1.3e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86254.1 - 2.5e-18 65.9 0.1 4.6e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86254.1 - 2.6e-11 43.8 0.0 1.5e-10 41.3 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain DEK_C PF08766.11 GBG86256.1 - 0.0091 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 DEK C terminal domain Terpene_synth PF01397.21 GBG86256.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Myb_DNA-bind_4 PF13837.6 GBG86256.1 - 0.22 11.9 1.3 0.33 11.4 0.1 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG86260.1 - 2.1e-33 115.2 0.1 2.9e-32 111.5 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86260.1 - 8.1e-17 61.5 0.0 1.9e-16 60.3 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG86260.1 - 0.00011 21.9 1.0 0.16 11.6 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG86260.1 - 0.011 16.1 0.6 0.95 9.9 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain TrbM PF07424.11 GBG86260.1 - 0.092 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 TrbM Myb_DNA-bind_4 PF13837.6 GBG86261.1 - 0.0004 20.7 1.5 0.0031 17.8 0.2 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG86261.1 - 0.029 14.7 2.7 1.2 9.4 0.2 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LapA_dom PF06305.11 GBG86262.1 - 0.016 15.0 0.3 0.025 14.4 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MAP17 PF15807.5 GBG86262.1 - 0.039 14.2 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SARAF PF06682.12 GBG86262.1 - 0.049 13.3 0.0 0.1 12.2 0.0 1.5 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis MRP-L46 PF11788.8 GBG86264.1 - 0.017 15.8 1.0 0.029 15.1 1.0 1.3 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Nop14 PF04147.12 GBG86264.1 - 0.2 9.8 11.6 0.24 9.6 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG86264.1 - 0.3 9.3 7.1 0.36 9.1 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG86264.1 - 0.4 10.1 12.0 0.56 9.6 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 GBG86264.1 - 2.7 7.3 14.8 3.7 6.9 14.8 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG86264.1 - 2.9 7.3 7.5 3.9 7.0 7.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RT_RNaseH_2 PF17919.1 GBG86265.1 - 4.3e-32 110.1 0.0 1.3e-31 108.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86265.1 - 4.1e-28 97.7 0.1 9.6e-28 96.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86265.1 - 2.2e-12 47.0 0.0 4.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG86265.1 - 0.0041 17.0 1.0 0.0084 16.1 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG86265.1 - 0.033 14.5 0.8 0.13 12.6 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein rve PF00665.26 GBG86265.1 - 0.043 14.0 0.1 0.13 12.5 0.1 1.9 1 0 0 1 1 1 0 Integrase core domain HepII_C PF18675.1 GBG86265.1 - 0.064 13.4 0.0 18 5.5 0.0 2.6 2 0 0 2 2 2 0 Heparinase II C-terminal domain zf-CCHC PF00098.23 GBG86265.1 - 2 8.6 4.9 3.6 7.8 4.9 1.4 1 0 0 1 1 1 0 Zinc knuckle CCD48 PF15799.5 GBG86266.1 - 0.0011 17.4 3.3 0.0017 16.8 3.3 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 DUF2385 PF09539.10 GBG86266.1 - 0.023 15.2 0.1 0.78 10.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) LCE6A PF15858.5 GBG86266.1 - 2.4 9.0 4.6 50 4.7 0.0 2.9 2 1 0 2 2 2 0 Late cornified envelope protein 6A family DUF3138 PF11336.8 GBG86266.1 - 2.5 6.6 5.0 3.9 6.0 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) O-FucT PF10250.9 GBG86267.1 - 2.1e-53 182.2 0.0 2.5e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF668 PF05003.12 GBG86268.1 - 0.83 10.2 3.6 18 5.9 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF668) GTP_EFTU PF00009.27 GBG86269.1 - 3.6e-51 173.5 0.0 5.8e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GBG86269.1 - 1.5e-37 128.3 0.0 3.4e-37 127.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GBG86269.1 - 8.8e-14 51.7 0.2 8.8e-14 51.7 0.2 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 SRPRB PF09439.10 GBG86269.1 - 0.0052 16.2 0.1 0.11 11.9 0.1 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GBG86269.1 - 0.018 15.1 0.3 0.081 13.0 0.3 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GBG86269.1 - 0.03 14.2 2.7 0.043 13.7 0.2 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AAA_22 PF13401.6 GBG86269.1 - 0.089 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RED_N PF07808.13 GBG86270.1 - 8.1e-75 251.4 0.5 8.1e-75 251.4 0.5 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 GBG86270.1 - 7.9e-41 139.0 8.2 7.9e-41 139.0 8.2 2.5 2 0 0 2 2 2 1 RED-like protein C-terminal region Lsm_interact PF05391.11 GBG86270.1 - 1.1 8.9 7.3 0.1 12.1 2.2 2.0 2 0 0 2 2 2 0 Lsm interaction motif RT_RNaseH_2 PF17919.1 GBG86271.1 - 6e-33 112.9 0.0 1.3e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86271.1 - 8.9e-30 103.1 0.1 1.7e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86271.1 - 1.1e-18 67.1 0.0 2.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86271.1 - 4.8e-14 52.6 0.0 1.1e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86271.1 - 7.8e-07 29.6 0.0 5.9e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG86271.1 - 0.001 18.6 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG86271.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86271.1 - 0.0013 19.4 0.0 0.0033 18.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG86271.1 - 0.01 15.6 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-CCHC_3 PF13917.6 GBG86271.1 - 0.021 14.8 2.0 0.067 13.2 2.0 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2 PF09337.10 GBG86271.1 - 0.075 13.3 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Syntaxin-6_N PF09177.11 GBG86271.1 - 0.16 12.6 0.0 0.54 10.8 0.0 1.9 2 0 0 2 2 1 0 Syntaxin 6, N-terminal RT_RNaseH_2 PF17919.1 GBG86272.1 - 5.7e-34 116.1 0.0 9.9e-34 115.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86272.1 - 5.3e-30 103.8 0.4 1e-29 102.9 0.4 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86272.1 - 2.2e-20 72.5 0.1 4.3e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86272.1 - 3.2e-14 53.1 0.3 1.4e-13 51.1 0.1 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG86272.1 - 0.00013 22.1 0.0 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG86273.1 - 7.5e-15 55.2 0.0 1.7e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86273.1 - 4.5e-13 49.1 0.1 8e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG86273.1 - 0.0033 17.9 0.0 0.013 16.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86273.1 - 0.11 13.2 0.0 0.4 11.4 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG86273.1 - 0.14 11.9 0.0 0.48 10.2 0.0 1.9 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF294_C PF10335.9 GBG86273.1 - 3.9 7.2 7.4 3.5 7.4 4.0 2.6 3 0 0 3 3 3 0 Putative nucleotidyltransferase substrate binding domain Remorin_C PF03763.13 GBG86275.1 - 1.2e-16 60.5 18.3 3.9e-16 58.9 18.3 2.0 1 0 0 1 1 1 1 Remorin, C-terminal region Iron_permease PF04120.12 GBG86275.1 - 0.65 9.8 4.5 1.2 8.9 4.5 1.4 1 0 0 1 1 1 0 Low affinity iron permease SelP_N PF04592.14 GBG86275.1 - 10 5.5 9.4 20 4.5 9.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF383 PF04063.14 GBG86276.1 - 2.4e-26 92.6 0.0 2.3e-25 89.4 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 GBG86276.1 - 1.3e-08 34.6 0.0 3.3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) K-cyclin_vir_C PF09080.10 GBG86276.1 - 0.16 12.4 0.9 0.49 10.8 0.2 2.1 1 1 1 2 2 2 0 K cyclin, C terminal RT_RNaseH_2 PF17919.1 GBG86277.1 - 4.7e-32 110.0 0.1 1.1e-31 108.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86277.1 - 8.4e-20 71.0 0.0 1.9e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86278.1 - 5.6e-43 147.0 0.1 1.2e-27 96.9 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86278.1 - 8.6e-33 112.8 0.0 2.2e-21 76.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86278.1 - 8.5e-31 106.0 0.0 6.3e-24 83.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86278.1 - 8.5e-19 67.4 1.0 1.7e-18 66.5 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86278.1 - 3.3e-09 37.0 0.0 9.9e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HSBP1 PF06825.12 GBG86278.1 - 3.3e-08 33.2 2.2 0.0001 22.0 0.1 2.9 2 0 0 2 2 2 2 Heat shock factor binding protein 1 RVP_2 PF08284.11 GBG86278.1 - 0.0031 17.3 0.0 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86278.1 - 0.0099 16.5 0.0 0.25 12.0 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Glyco_hydro_32N PF00251.20 GBG86279.1 - 6.8e-78 262.3 0.0 1.1e-77 261.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DUF659 PF04937.15 GBG86279.1 - 6.7e-46 155.9 0.0 1.8e-30 105.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Glyco_hydro_32C PF08244.12 GBG86279.1 - 4.2e-15 56.1 0.0 3.3e-13 49.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Biotin_carb_N PF00289.22 GBG86279.1 - 0.051 14.1 0.0 6.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Biotin carboxylase, N-terminal domain SDA1 PF05285.12 GBG86280.1 - 8.4e-05 22.2 32.5 9.9e-05 21.9 32.5 1.1 1 0 0 1 1 1 1 SDA1 SpoIIIAH PF12685.7 GBG86280.1 - 0.015 15.1 12.3 0.021 14.6 12.3 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 GBG86280.1 - 0.058 11.6 36.4 0.071 11.3 36.4 1.1 1 0 0 1 1 1 0 Nop14-like family Serinc PF03348.15 GBG86280.1 - 0.075 12.0 1.2 0.1 11.5 1.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Cwf_Cwc_15 PF04889.12 GBG86280.1 - 0.25 11.0 31.1 0.38 10.4 31.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GBG86280.1 - 0.39 10.0 31.0 0.7 9.2 31.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 GBG86280.1 - 0.51 9.3 8.7 0.63 9.0 8.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 GBG86280.1 - 1.1 8.0 14.4 1.2 7.8 14.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.11 GBG86280.1 - 1.3 8.6 33.1 0.031 13.9 26.9 1.4 2 0 0 2 2 2 0 PPP4R2 Zip PF02535.22 GBG86280.1 - 1.8 7.7 10.9 2.3 7.3 10.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 GBG86280.1 - 2.8 7.2 38.7 3.5 6.9 38.7 1.1 1 0 0 1 1 1 0 BUD22 SURF2 PF05477.11 GBG86280.1 - 3.7 7.2 18.6 5.6 6.6 18.6 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) HSP70 PF00012.20 GBG86280.1 - 3.7 5.6 10.1 3.8 5.6 10.1 1.1 1 0 0 1 1 1 0 Hsp70 protein Presenilin PF01080.17 GBG86280.1 - 5.9 5.6 17.3 7.3 5.2 17.3 1.2 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 GBG86280.1 - 6.6 6.3 19.9 9.3 5.8 19.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PA26 PF04636.13 GBG86280.1 - 6.7 5.5 7.4 8.1 5.2 7.4 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FRQ PF09421.10 GBG86280.1 - 7.4 4.5 18.0 9.3 4.1 18.0 1.0 1 0 0 1 1 1 0 Frequency clock protein NPR3 PF03666.13 GBG86280.1 - 7.6 5.2 13.1 9.4 4.9 13.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3444 PF11926.8 GBG86282.1 - 1.2e-44 152.5 0.0 1.1e-24 87.2 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF3444) Thioredoxin PF00085.20 GBG86283.1 - 2.5e-64 213.7 0.0 1.7e-31 108.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 GBG86283.1 - 3.4e-15 56.7 0.2 6.5e-15 55.8 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 GBG86283.1 - 4.5e-13 49.2 0.0 6.8e-06 25.6 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GBG86283.1 - 3.9e-11 43.3 0.6 0.00052 20.4 0.0 3.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG86283.1 - 3.3e-07 30.5 0.0 0.024 15.0 0.0 3.4 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 GBG86283.1 - 2.5e-06 27.6 0.1 0.07 13.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 GBG86283.1 - 6.7e-06 26.0 0.0 0.034 14.0 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 GBG86283.1 - 0.0016 18.2 0.4 0.072 12.8 0.0 2.3 2 0 0 2 2 2 1 Redoxin HyaE PF07449.11 GBG86283.1 - 0.0026 17.7 0.0 3.2 7.7 0.0 2.8 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 GBG86283.1 - 0.0087 15.9 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 GBG86283.1 - 0.0094 15.7 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin RT_RNaseH PF17917.1 GBG86285.1 - 8.1e-23 80.7 0.3 2.2e-22 79.3 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86285.1 - 1.1e-18 67.5 0.2 2.2e-18 66.6 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86285.1 - 2.6e-13 49.8 0.1 5.6e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG86285.1 - 3.5e-13 49.5 0.0 8.5e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86285.1 - 2.1e-07 31.1 0.2 4.2e-06 27.0 0.0 2.9 3 1 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG86285.1 - 0.00021 21.5 0.0 0.00046 20.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RBFA PF02033.18 GBG86287.1 - 6.5e-11 42.6 0.0 1.7e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Ribosome-binding factor A Pro_dh PF01619.18 GBG86288.1 - 3.1e-65 220.7 0.0 5.5e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Proline dehydrogenase DUF1758 PF05585.12 GBG86288.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) NAD_Gly3P_dh_C PF07479.14 GBG86289.1 - 0.041 14.2 0.0 0.045 14.0 0.0 1.0 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DUF659 PF04937.15 GBG86291.1 - 2e-30 105.7 0.0 3.2e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) AT_hook PF02178.19 GBG86291.1 - 0.82 9.7 7.6 3 8.0 7.6 2.1 1 0 0 1 1 1 0 AT hook motif Thioredoxin PF00085.20 GBG86292.1 - 1.2e-65 218.0 0.0 3.2e-32 110.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 GBG86292.1 - 3.6e-23 82.3 2.5 6.6e-23 81.4 2.5 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 GBG86292.1 - 1.4e-12 47.6 0.0 1.7e-05 24.3 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GBG86292.1 - 1.4e-10 41.6 0.4 0.00063 20.2 0.1 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GBG86292.1 - 1.7e-07 31.3 0.3 0.0058 16.8 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 GBG86292.1 - 5.1e-07 29.6 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 GBG86292.1 - 7.7e-07 29.4 0.0 0.052 13.9 0.0 3.3 2 2 1 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 GBG86292.1 - 0.00016 21.4 0.4 0.026 14.2 0.0 2.3 2 0 0 2 2 2 1 Redoxin HyaE PF07449.11 GBG86292.1 - 0.0047 16.9 0.0 4.9 7.2 0.0 2.9 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 GBG86292.1 - 0.021 14.6 0.0 0.67 9.7 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 GBG86292.1 - 0.065 13.0 0.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin PRD PF00874.20 GBG86293.1 - 0.16 12.3 0.1 0.29 11.4 0.1 1.3 1 0 0 1 1 1 0 PRD domain MMR_HSR1 PF01926.23 GBG86294.1 - 1.1e-14 54.5 0.0 6.9e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG86294.1 - 1.1e-05 25.0 0.0 0.00014 21.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GBG86294.1 - 1.7e-05 24.8 0.0 0.0038 17.1 0.0 2.5 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 GBG86294.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 GBG86294.1 - 0.025 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Dynamin family Arf PF00025.21 GBG86294.1 - 0.098 12.1 0.0 1.9 7.9 0.0 2.2 1 1 0 2 2 2 0 ADP-ribosylation factor family TSGP1 PF07771.11 GBG86294.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Tick salivary peptide group 1 Spike_rec_bind PF09408.10 GBG86295.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Spike receptor binding domain Rep_fac-A_3 PF08661.11 GBG86296.1 - 9.4e-16 58.1 0.0 1e-15 58.0 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Band_7 PF01145.25 GBG86297.1 - 5e-28 98.3 0.4 7e-28 97.8 0.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ribosomal_S3Ae PF01015.18 GBG86297.1 - 0.044 13.4 0.5 0.074 12.6 0.5 1.3 1 0 0 1 1 1 0 Ribosomal S3Ae family WD40 PF00400.32 GBG86298.1 - 5.6e-27 93.5 9.9 7.9e-06 26.5 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG86298.1 - 1.6e-15 57.2 3.4 3.8e-05 23.9 0.1 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG86298.1 - 0.00051 20.0 0.0 1.3 8.8 0.0 3.3 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GBG86298.1 - 0.014 14.4 1.4 1.2 8.0 1.2 3.1 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 GBG86298.1 - 0.027 13.2 0.1 1.8 7.3 0.0 2.4 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.32 GBG86299.1 - 1.3e-18 67.0 11.5 7.1e-06 26.7 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG86299.1 - 1.2e-14 54.3 3.9 7.1e-05 23.0 0.2 3.8 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 GBG86299.1 - 0.0073 15.1 0.1 1 8.0 0.0 2.6 2 1 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF4347 PF14252.6 GBG86299.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) DDE_Tnp_4 PF13359.6 GBG86300.1 - 1.1e-34 119.4 0.0 1.6e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86300.1 - 2.3e-13 50.2 0.0 4.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG86300.1 - 8.5e-06 25.6 0.2 6.3e-05 22.7 0.2 2.2 1 1 0 1 1 1 1 Transposase DDE domain DcuC PF03606.15 GBG86300.1 - 0.085 11.3 2.4 0.11 11.0 2.4 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Myb_DNA-bind_4 PF13837.6 GBG86301.1 - 1.6e-05 25.2 2.4 2.5e-05 24.5 2.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TetR_C_24 PF17932.1 GBG86301.1 - 0.089 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RT_RNaseH_2 PF17919.1 GBG86302.1 - 1.6e-19 69.7 0.0 3.7e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86302.1 - 2.3e-17 63.2 0.0 5.6e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86302.1 - 2.5e-13 50.3 0.0 1.1e-12 48.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86302.1 - 2.3e-11 43.6 0.5 7e-11 42.1 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG86302.1 - 9e-08 32.6 0.1 2.7e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG86302.1 - 3.5e-07 30.0 0.0 7.9e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG86302.1 - 1.1e-06 29.2 0.1 3.4e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG86302.1 - 0.056 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease Treslin_N PF15292.6 GBG86303.1 - 3.2e-05 22.5 0.0 0.12 10.7 0.0 2.2 2 0 0 2 2 2 2 Treslin N-terminus Peptidase_C2 PF00648.21 GBG86303.1 - 0.064 12.3 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Calpain family cysteine protease RT_RNaseH PF17917.1 GBG86304.1 - 1.5e-22 79.9 0.0 6.2e-22 77.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86304.1 - 2.2e-21 75.7 0.0 5.9e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86304.1 - 9.5e-17 60.9 1.7 1.6e-16 60.2 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86304.1 - 1.1e-13 51.4 0.0 4.3e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG86304.1 - 0.54 10.5 3.1 0.33 11.2 0.8 1.9 2 0 0 2 2 2 0 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG86305.1 - 1.6e-14 53.8 0.1 3.8e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86305.1 - 2e-07 31.2 0.0 4.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG86305.1 - 4.7e-05 23.0 0.0 9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG86305.1 - 0.0026 18.0 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger FA_hydroxylase PF04116.13 GBG86306.1 - 0.0019 18.5 0.0 0.0031 17.9 0.0 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DUF659 PF04937.15 GBG86307.1 - 1.6e-08 34.6 0.0 2.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Connexin PF00029.19 GBG86307.1 - 0.0002 21.2 0.3 0.0002 21.2 0.3 2.1 2 0 0 2 2 2 1 Connexin Na_trans_assoc PF06512.13 GBG86307.1 - 0.001 19.4 5.3 0.001 19.4 5.3 3.0 3 0 0 3 3 3 1 Sodium ion transport-associated BUD22 PF09073.10 GBG86307.1 - 0.0024 17.3 20.3 0.0024 17.3 20.3 3.0 3 0 0 3 3 3 1 BUD22 Sigma70_ner PF04546.13 GBG86307.1 - 0.003 17.5 9.5 0.003 17.5 9.5 2.6 3 0 0 3 3 3 1 Sigma-70, non-essential region CDC45 PF02724.14 GBG86307.1 - 0.02 13.2 36.5 0.045 12.1 17.9 2.1 2 0 0 2 2 2 0 CDC45-like protein Mpp10 PF04006.12 GBG86307.1 - 0.13 10.7 34.2 0.0095 14.4 22.3 2.2 2 0 0 2 2 2 0 Mpp10 protein EIIBC-GUT_N PF03612.14 GBG86307.1 - 0.8 9.4 4.1 2.1 8.0 4.1 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CLN3 PF02487.17 GBG86307.1 - 1.6 7.7 3.9 3.1 6.8 3.9 1.4 1 0 0 1 1 1 0 CLN3 protein Mem_trans PF03547.18 GBG86307.1 - 2.2 6.6 4.9 0.19 10.1 0.4 1.4 2 0 0 2 2 2 0 Membrane transport protein DNA_pol_phi PF04931.13 GBG86307.1 - 2.4 6.2 34.2 0.0069 14.6 22.8 2.4 2 0 0 2 2 2 0 DNA polymerase phi SDA1 PF05285.12 GBG86307.1 - 2.9 7.2 42.1 0.067 12.6 25.0 2.3 2 0 0 2 2 2 0 SDA1 SAPS PF04499.15 GBG86307.1 - 3.4 6.4 14.9 0.14 10.9 2.3 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein RAB3GAP2_C PF14656.6 GBG86307.1 - 4.4 5.4 6.6 7.5 4.7 6.6 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Neur_chan_memb PF02932.16 GBG86307.1 - 4.4 7.3 10.8 1.4 8.9 0.2 2.9 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region TLP-20 PF06088.11 GBG86307.1 - 4.9 7.0 13.3 1.1 9.2 6.9 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Apt1 PF10351.9 GBG86307.1 - 5.3 5.8 26.9 2.1 7.1 10.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF1682 PF07946.14 GBG86307.1 - 6.1 6.0 17.4 0.3 10.2 11.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Macoilin PF09726.9 GBG86307.1 - 6.1 5.3 15.9 5 5.6 4.4 2.2 2 0 0 2 2 2 0 Macoilin family SpoIIP PF07454.11 GBG86307.1 - 6.2 6.2 16.9 0.13 11.7 9.8 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SATase_N PF06426.14 GBG86308.1 - 2.6e-33 114.5 0.0 4.1e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 GBG86308.1 - 9.2e-06 25.2 7.6 0.01 15.5 1.0 2.6 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GBG86308.1 - 2 8.3 8.8 0.33 10.7 2.7 2.4 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase gag-asp_proteas PF13975.6 GBG86309.1 - 0.0029 18.1 0.0 0.014 15.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86309.1 - 0.0036 17.9 0.0 0.022 15.4 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Chromo PF00385.24 GBG86309.1 - 0.0038 17.1 0.3 0.013 15.4 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG86309.1 - 0.21 11.4 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease HRXXH PF13933.6 GBG86310.1 - 0.097 12.2 0.0 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 Putative peptidase family Med8 PF10232.9 GBG86311.1 - 8.2e-05 22.3 0.1 0.00018 21.2 0.1 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Acetyltransf_1 PF00583.25 GBG86313.1 - 1.5e-15 57.5 0.1 1.8e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GBG86313.1 - 6.8e-11 42.2 0.0 8.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GBG86313.1 - 8.6e-11 42.1 0.6 1.3e-10 41.6 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG86313.1 - 6.7e-07 29.2 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GBG86313.1 - 8.4e-05 22.6 0.1 0.00013 22.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GBG86313.1 - 0.003 17.7 0.1 0.0037 17.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ciart PF15673.5 GBG86313.1 - 0.11 11.8 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor RT_RNaseH PF17917.1 GBG86314.1 - 5.2e-19 68.5 0.0 8.9e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86314.1 - 4.2e-11 42.8 0.0 8.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG86314.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4746 PF15928.5 GBG86314.1 - 0.067 12.6 9.2 0.17 11.3 9.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) gag-asp_proteas PF13975.6 GBG86314.1 - 0.17 12.5 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CDC45 PF02724.14 GBG86314.1 - 0.24 9.6 11.5 0.35 9.1 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 GBG86314.1 - 0.6 10.4 18.6 1.3 9.3 18.6 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RR_TM4-6 PF06459.12 GBG86314.1 - 2 8.2 10.2 3.6 7.3 10.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG86314.1 - 2 7.8 18.8 3.6 6.9 18.8 1.3 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG86314.1 - 2.6 7.7 13.4 21 4.7 13.9 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Na_trans_assoc PF06512.13 GBG86314.1 - 2.7 8.2 12.7 5.6 7.2 12.7 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 GBG86314.1 - 3 7.1 16.2 5.3 6.3 16.2 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG86314.1 - 3.8 5.6 19.1 5.5 5.1 19.1 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 GBG86314.1 - 4.6 7.3 13.1 8.6 6.4 13.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YL1 PF05764.13 GBG86314.1 - 8.8 6.4 25.0 6.9 6.7 23.0 1.7 2 0 0 2 2 2 0 YL1 nuclear protein SPOUT_MTase PF02590.17 GBG86315.1 - 0.18 11.8 1.3 0.24 11.3 0.5 1.6 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase DUF4140 PF13600.6 GBG86315.1 - 4.1 7.9 8.3 17 6.0 7.3 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cep57_MT_bd PF06657.13 GBG86315.1 - 7.1 7.2 9.2 3.5 8.1 4.4 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Myb_DNA-bind_4 PF13837.6 GBG86316.1 - 5.7e-06 26.6 0.4 1.2e-05 25.5 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG86316.1 - 0.0038 17.3 0.1 0.0071 16.4 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4690 PF15756.5 GBG86317.1 - 0.048 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage MHYT PF03707.16 GBG86318.1 - 0.003 17.7 1.7 0.72 10.1 0.2 2.5 2 0 0 2 2 2 2 Bacterial signalling protein N terminal repeat Herpes_gE PF02480.16 GBG86318.1 - 0.0053 15.6 0.0 0.0085 14.9 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Fasciclin PF02469.22 GBG86318.1 - 0.026 14.8 0.1 0.051 13.8 0.1 1.5 1 0 0 1 1 1 0 Fasciclin domain Amnionless PF14828.6 GBG86318.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Amnionless DUF4381 PF14316.6 GBG86318.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMEM154 PF15102.6 GBG86318.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 GBG86318.1 - 0.18 12.7 0.2 0.39 11.6 0.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BatA PF07584.11 GBG86318.1 - 0.22 11.9 3.1 0.32 11.4 0.0 2.3 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Es2 PF09751.9 GBG86319.1 - 0.0033 17.2 12.8 0.0044 16.8 12.8 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 EBV-NA3 PF05009.12 GBG86319.1 - 0.081 12.4 3.2 0.13 11.8 3.2 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC27 PF09507.10 GBG86319.1 - 0.12 11.8 23.3 0.14 11.5 23.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 VIR_N PF15912.5 GBG86319.1 - 6.8 6.2 10.0 12 5.4 10.0 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal gag-asp_proteas PF13975.6 GBG86320.1 - 1.2e-07 32.2 0.1 2.7e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86320.1 - 1.9e-05 25.2 0.1 3.8e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG86320.1 - 0.0002 21.2 0.1 0.00029 20.6 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG86320.1 - 0.0038 17.0 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Nop14 PF04147.12 GBG86320.1 - 0.82 7.8 54.1 1.1 7.3 54.1 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG86321.1 - 3.3e-14 52.7 0.0 8.8e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86321.1 - 1.4e-13 51.0 0.0 3.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86321.1 - 9.2e-09 35.1 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG86321.1 - 1.3e-06 28.8 0.2 7.7e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86321.1 - 0.00024 21.7 0.0 0.00091 19.8 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG86321.1 - 0.0038 17.4 0.0 0.0095 16.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.20 GBG86321.1 - 0.0087 16.3 0.0 0.031 14.6 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86321.1 - 0.14 11.9 0.9 0.29 11.0 0.9 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF1835 PF08874.10 GBG86321.1 - 0.78 10.0 3.6 9.4 6.5 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1835) Jnk-SapK_ap_N PF09744.9 GBG86321.1 - 2.5 8.3 13.8 0.092 13.0 3.5 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CENP-N PF05238.13 GBG86321.1 - 7.7 5.7 8.3 2.1 7.5 3.7 2.2 2 1 0 2 2 2 0 Kinetochore protein CHL4 like Pkinase PF00069.25 GBG86322.1 - 1.8e-38 132.4 0.0 3.4e-38 131.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG86322.1 - 3.4e-37 128.2 0.0 5.4e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG86322.1 - 0.0048 15.7 1.0 0.014 14.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GBG86322.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GBG86322.1 - 0.016 15.1 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM PF10378.9 GBG86323.1 - 0.19 11.5 0.8 6.2 6.6 0.3 2.8 2 0 0 2 2 2 0 Putative RRM domain RVT_1 PF00078.27 GBG86325.1 - 6.7e-28 97.7 0.0 1.1e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86325.1 - 2.1e-19 69.4 0.0 9.9e-16 57.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86325.1 - 2.7e-16 59.4 1.2 7.7e-16 57.9 0.0 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG86325.1 - 4.5e-13 49.4 0.0 1.5e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG86325.1 - 1.3e-11 44.2 0.0 2.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG86325.1 - 2e-06 28.0 0.0 5.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG86325.1 - 5.2e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG86326.1 - 0.0003 21.0 0.1 0.00067 19.9 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF2254 PF10011.9 GBG86327.1 - 0.06 12.2 0.2 0.69 8.7 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) ER PF01133.17 GBG86327.1 - 0.12 12.4 1.0 11 6.2 1.0 2.8 1 1 0 1 1 1 0 Enhancer of rudimentary RT_RNaseH PF17917.1 GBG86329.1 - 4.2e-34 117.0 0.2 3.2e-29 101.3 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86329.1 - 5.7e-30 103.3 0.0 1.6e-29 101.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase BET PF17035.5 GBG86329.1 - 2.6e-25 88.4 0.7 8.9e-25 86.7 0.1 2.4 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 GBG86329.1 - 2.8e-18 65.8 0.0 6.1e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Integrase_H2C2 PF17921.1 GBG86329.1 - 4.2e-17 62.0 0.0 1.3e-16 60.5 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86329.1 - 0.00078 19.6 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG86329.1 - 0.00095 19.4 0.2 0.61 10.3 0.0 2.6 1 1 1 2 2 2 2 Integrase core domain RT_RNaseH PF17917.1 GBG86330.1 - 4.2e-34 117.0 0.2 3.2e-29 101.3 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86330.1 - 5.7e-30 103.3 0.0 1.6e-29 101.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase BET PF17035.5 GBG86330.1 - 2.6e-25 88.4 0.7 8.9e-25 86.7 0.1 2.4 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 GBG86330.1 - 2.8e-18 65.8 0.0 6.1e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Integrase_H2C2 PF17921.1 GBG86330.1 - 4.2e-17 62.0 0.0 1.3e-16 60.5 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86330.1 - 0.00078 19.6 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG86330.1 - 0.00094 19.4 0.2 0.61 10.3 0.0 2.6 1 1 1 2 2 2 2 Integrase core domain zf-CCHC PF00098.23 GBG86333.1 - 1.1e-06 28.4 1.9 2e-06 27.6 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86333.1 - 0.039 13.8 0.9 0.075 12.9 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle MTBP_mid PF14919.6 GBG86335.1 - 5.8 6.0 4.8 19 4.3 0.2 2.7 1 1 2 3 3 3 0 MDM2-binding Podoplanin PF05808.11 GBG86335.1 - 7.4 6.7 6.6 10 6.2 0.2 2.7 1 1 3 4 4 4 0 Podoplanin RVT_1 PF00078.27 GBG86336.1 - 3.7e-32 111.7 0.0 5e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CLIP1_ZNF PF16641.5 GBG86336.1 - 0.022 14.6 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 CLIP1 zinc knuckle GAIN PF16489.5 GBG86336.1 - 0.24 10.8 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain Nucleotid_trans PF03407.16 GBG86339.1 - 1.3e-31 110.2 0.0 3.1e-29 102.5 0.0 2.5 2 0 0 2 2 2 2 Nucleotide-diphospho-sugar transferase RVT_1 PF00078.27 GBG86340.1 - 6.1e-27 94.6 0.0 1e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86340.1 - 1.2e-25 89.4 0.0 1.1e-24 86.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86340.1 - 9.1e-25 87.0 0.0 3.8e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF2249 PF10006.9 GBG86340.1 - 0.083 12.8 0.0 2.3 8.1 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) zf-CCHC PF00098.23 GBG86341.1 - 5.1e-06 26.3 3.2 7.7e-06 25.8 3.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG86341.1 - 0.00055 20.2 0.2 0.0026 18.0 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG86341.1 - 0.0086 15.9 4.1 0.015 15.1 4.1 1.4 1 0 0 1 1 1 1 Zinc knuckle SlyX PF04102.12 GBG86342.1 - 0.008 16.8 0.2 0.008 16.8 0.2 3.3 3 1 0 3 3 3 1 SlyX WTX PF09422.10 GBG86342.1 - 0.1 11.7 5.3 0.04 13.0 2.9 1.4 1 1 0 1 1 1 0 WTX protein FAM76 PF16046.5 GBG86342.1 - 2.8 7.2 6.8 3.8 6.8 6.8 1.3 1 0 0 1 1 1 0 FAM76 protein rve PF00665.26 GBG86343.1 - 1.2e-13 51.3 0.0 2.6e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86343.1 - 0.0003 21.3 0.0 0.00096 19.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG86343.1 - 0.0028 18.0 0.0 0.0075 16.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86343.1 - 0.0048 17.5 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 GBG86343.1 - 0.0054 16.5 0.0 0.02 14.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG86343.1 - 0.026 14.8 0.3 0.15 12.4 0.1 2.2 1 1 0 2 2 2 0 Retrotransposon gag protein ATG16 PF08614.11 GBG86343.1 - 0.44 10.7 4.2 0.27 11.4 1.0 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) rve PF00665.26 GBG86344.1 - 3e-15 56.4 0.0 8.1e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86344.1 - 1.3e-10 41.2 0.0 4e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG86344.1 - 0.00042 19.9 0.0 0.00085 18.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG86344.1 - 0.0068 16.2 0.0 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG86345.1 - 6e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG86345.1 - 0.00012 22.6 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86345.1 - 0.00015 22.3 0.0 0.00027 21.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG86345.1 - 0.00095 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RNR_Alpha PF17975.1 GBG86346.1 - 0.14 12.7 0.3 0.14 12.7 0.3 2.3 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain Nup54_57_C PF18570.1 GBG86346.1 - 0.15 11.7 1.5 0.39 10.4 1.5 1.7 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain PIEZO PF15917.5 GBG86346.1 - 0.68 9.4 10.9 0.55 9.7 9.6 1.6 2 0 0 2 2 2 0 Piezo ERM PF00769.19 GBG86346.1 - 4.6 7.0 27.4 15 5.3 27.4 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family RT_RNaseH PF17917.1 GBG86347.1 - 5.7e-23 81.2 0.0 1.4e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86347.1 - 8e-23 80.4 0.0 1.9e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86347.1 - 1.3e-12 47.7 0.5 6.4e-08 32.4 0.1 2.9 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86347.1 - 2.3e-08 34.3 0.0 7.2e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG86347.1 - 9.1e-08 32.0 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86347.1 - 1.1e-06 29.1 0.0 4.1e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86347.1 - 2e-05 25.1 0.2 0.00019 21.9 0.0 2.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG86347.1 - 0.0027 17.9 0.0 0.015 15.5 0.0 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein Tudor-knot PF11717.8 GBG86347.1 - 0.0041 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG86347.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG86348.1 - 3.6e-21 75.4 0.0 3e-20 72.5 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86348.1 - 4.8e-19 68.2 0.0 1.1e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86348.1 - 2e-13 50.2 0.1 4.9e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG86348.1 - 0.0013 18.3 0.0 0.0032 17.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MazG_C PF18722.1 GBG86351.1 - 0.025 14.1 0.4 0.046 13.2 0.4 1.3 1 0 0 1 1 1 0 MazG C-terminal domain HALZ PF02183.18 GBG86352.1 - 0.031 14.5 1.2 0.1 12.9 1.2 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 GBG86352.1 - 0.1 12.7 6.1 0.089 12.9 2.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 GBG86352.1 - 0.19 11.9 1.4 0.52 10.5 1.4 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 GBG86352.1 - 0.29 10.9 7.8 0.14 12.0 1.8 2.5 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 GBG86352.1 - 0.61 10.6 5.6 1.6 9.2 5.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapB RVT_1 PF00078.27 GBG86353.1 - 3.3e-33 115.1 0.0 5.7e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86353.1 - 2e-31 108.0 0.0 3.9e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86353.1 - 2.7e-27 95.1 0.0 5.1e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86353.1 - 5.5e-12 45.6 0.0 3.6e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86353.1 - 8.5e-09 35.6 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG86353.1 - 0.00012 22.7 0.0 0.00024 21.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86353.1 - 0.00017 22.1 0.0 0.00032 21.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rhamno_transf PF11316.8 GBG86353.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase RVP_2 PF08284.11 GBG86353.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86353.1 - 0.032 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease GSHPx PF00255.19 GBG86353.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione peroxidase RT_RNaseH_2 PF17919.1 GBG86354.1 - 7.4e-27 93.3 0.0 1.4e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86354.1 - 7.5e-24 84.0 0.0 1.5e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86354.1 - 3.3e-12 46.6 0.1 9.9e-11 41.9 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG86354.1 - 5.4e-08 33.4 0.0 9.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86354.1 - 8.6e-08 32.6 0.0 1.6e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86354.1 - 3.2e-05 23.7 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG86354.1 - 0.00019 21.0 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG86354.1 - 0.0042 16.9 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Defensin_5 PF18251.1 GBG86356.1 - 1.6 8.9 16.1 2.6 8.2 1.8 4.4 3 1 1 4 4 4 0 Fungal defensin Copsin RT_RNaseH_2 PF17919.1 GBG86358.1 - 3.5e-24 84.7 0.0 7.6e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86358.1 - 9.3e-23 80.5 0.0 2.3e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86358.1 - 0.00014 21.4 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S41 PF03572.18 GBG86361.1 - 1.9e-17 63.3 0.0 6.5e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 GBG86361.1 - 2.7e-09 36.7 0.1 9.4e-09 35.0 0.1 2.0 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GBG86361.1 - 2.7e-06 27.6 0.0 6.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GBG86361.1 - 0.00014 22.2 0.0 0.00038 20.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 GBG86361.1 - 0.095 12.7 0.0 0.35 10.9 0.0 2.1 1 0 0 1 1 1 0 Tricorn protease PDZ domain DAGAT PF03982.13 GBG86362.1 - 5.1e-31 107.7 0.1 7e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 GBG86362.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase Goodbye PF17109.5 GBG86364.1 - 0.0058 17.1 0.3 0.33 11.4 0.1 2.3 1 1 1 2 2 2 2 fungal STAND N-terminal Goodbye domain FERM_f0 PF16511.5 GBG86364.1 - 1.8 8.9 15.3 13 6.2 0.5 4.6 1 1 3 4 4 4 0 N-terminal or F0 domain of Talin-head FERM RVP_2 PF08284.11 GBG86365.1 - 2.6e-06 27.3 0.0 6.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86365.1 - 6.2e-06 26.8 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86365.1 - 0.00021 21.8 0.0 0.00044 20.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86365.1 - 0.039 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease TolA_bind_tri PF16331.5 GBG86365.1 - 1.7 8.8 6.3 3.1 7.9 6.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation RT_RNaseH_2 PF17919.1 GBG86367.1 - 4.5e-27 94.0 0.0 7.8e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86367.1 - 1.8e-24 86.1 0.0 3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86367.1 - 8.9e-14 51.5 0.1 1.4e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3285 PF11688.8 GBG86367.1 - 1.4 8.9 3.6 30 4.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) OMPdecase PF00215.24 GBG86368.1 - 7.1e-73 244.9 0.0 1e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 GBG86368.1 - 1.4e-10 41.0 0.4 2.6e-10 40.0 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Mito_fiss_reg PF05308.11 GBG86368.1 - 0.14 12.2 1.3 0.23 11.5 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 GBG86368.1 - 1.1 8.7 6.8 1.7 8.0 6.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG86368.1 - 3.9 7.5 11.7 7.9 6.5 11.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3336 PF11815.8 GBG86370.1 - 2.2e-19 69.5 0.0 3.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GBG86370.1 - 2.7e-18 66.9 0.0 1.4e-17 64.6 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase DUF1674 PF07896.12 GBG86371.1 - 2.4e-14 53.6 4.5 2.5e-14 53.5 2.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Ribosomal_L17 PF01196.19 GBG86372.1 - 1.2e-32 112.7 2.2 1.6e-32 112.3 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 TraC PF07820.12 GBG86372.1 - 0.24 11.7 1.7 0.3 11.4 0.2 2.0 2 1 0 2 2 2 0 TraC-like protein POPLD PF08170.12 GBG86373.1 - 1.5e-11 44.5 0.3 5.8e-11 42.6 0.3 2.1 1 0 0 1 1 1 1 POPLD (NUC188) domain POP1 PF06978.11 GBG86373.1 - 4.1e-09 36.7 0.4 4.1e-09 36.7 0.4 4.1 4 1 0 4 4 4 2 Ribonucleases P/MRP protein subunit POP1 ThiS PF02597.20 GBG86375.1 - 3e-15 56.6 0.0 3.4e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 ThiS family RT_RNaseH_2 PF17919.1 GBG86376.1 - 1e-35 121.8 0.0 2e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86376.1 - 4.5e-33 113.7 0.0 7.7e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sec1 PF00995.23 GBG86377.1 - 3.4e-113 379.9 0.0 3.9e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pec_lyase_C PF00544.19 GBG86378.1 - 5.9e-22 78.3 6.6 5.9e-22 78.3 6.6 2.2 2 1 0 2 2 2 1 Pectate lyase Beta_helix PF13229.6 GBG86378.1 - 6.7e-06 26.0 11.2 1.4e-05 25.0 11.2 1.6 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG86378.1 - 0.025 13.9 1.5 0.047 13.0 1.5 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) SDA1 PF05285.12 GBG86381.1 - 0.041 13.3 7.3 0.04 13.4 7.3 1.1 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 GBG86381.1 - 0.07 13.4 11.1 0.11 12.8 11.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GBG86381.1 - 0.083 11.1 8.8 0.08 11.2 8.8 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG86381.1 - 0.32 9.2 7.1 0.33 9.2 7.1 1.0 1 0 0 1 1 1 0 CDC45-like protein GATase_6 PF13522.6 GBG86382.1 - 2.8e-08 34.0 0.0 1e-07 32.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GBG86382.1 - 3.6e-05 22.8 0.1 0.0018 17.3 0.0 2.7 2 1 1 3 3 3 1 Glutamine amidotransferases class-II Retrotrans_gag PF03732.17 GBG86383.1 - 0.00019 21.7 0.2 0.00078 19.7 0.1 2.0 1 1 0 1 1 1 1 Retrotransposon gag protein FAT PF02259.23 GBG86383.1 - 0.061 12.5 0.1 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 FAT domain RT_RNaseH PF17917.1 GBG86384.1 - 5.3e-23 81.3 0.0 1.4e-22 80.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86384.1 - 3.2e-21 75.2 0.0 8.5e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86384.1 - 4.6e-15 55.5 0.2 1.1e-14 54.3 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG86384.1 - 7e-10 38.8 1.1 0.00035 20.1 0.2 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG86384.1 - 7e-07 29.8 0.0 1.4e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86384.1 - 5.4e-06 26.9 0.0 1.2e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG86384.1 - 0.00012 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86384.1 - 0.00069 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG86384.1 - 0.0018 18.1 0.1 0.0033 17.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PSCyt2 PF07583.11 GBG86384.1 - 0.033 14.1 0.1 1.7 8.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1549) zf-CCHC PF00098.23 GBG86385.1 - 1.3e-05 25.1 4.4 2.3e-05 24.3 4.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG86385.1 - 0.0083 15.8 0.7 0.017 14.8 0.7 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG86385.1 - 0.17 11.7 4.0 0.35 10.7 4.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG86386.1 - 2.4e-09 37.4 0.6 2.4e-09 37.4 0.6 2.2 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Imm32 PF15566.6 GBG86387.1 - 0.19 11.5 0.1 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 32 DUF659 PF04937.15 GBG86388.1 - 6.2e-06 26.2 0.0 9.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG86389.1 - 4.1e-16 59.3 0.0 9.8e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain WD40 PF00400.32 GBG86389.1 - 2.3e-15 56.7 4.1 0.00011 22.9 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 GBG86389.1 - 7.4e-08 31.3 0.0 1.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 GBG86389.1 - 0.00036 20.8 0.0 0.15 12.4 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG86389.1 - 0.0076 15.0 0.4 0.37 9.4 0.1 2.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Lactonase PF10282.9 GBG86389.1 - 0.081 12.2 0.1 0.35 10.1 0.0 2.0 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Apt1 PF10351.9 GBG86389.1 - 3.9 6.2 9.0 2.3 7.0 7.2 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain IceA2 PF05862.11 GBG86390.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein Chromo PF00385.24 GBG86390.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FAM199X PF15814.5 GBG86390.1 - 1.3 8.0 3.8 2.3 7.2 3.8 1.3 1 0 0 1 1 1 0 Protein family FAM199X bZIP_C PF12498.8 GBG86390.1 - 3 8.9 11.5 3.5 8.6 1.3 2.8 3 0 0 3 3 3 0 Basic leucine-zipper C terminal Fmp27 PF10344.9 GBG86391.1 - 0.23 9.5 8.5 0.34 9.0 8.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Nucleoplasmin PF03066.15 GBG86391.1 - 0.4 11.2 2.8 0.42 11.1 0.1 2.2 1 1 1 2 2 2 0 Nucleoplasmin/nucleophosmin domain DUF1681 PF07933.14 GBG86393.1 - 0.0045 16.7 0.2 0.0045 16.7 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) Ribosomal_60s PF00428.19 GBG86393.1 - 0.063 13.9 12.3 0.097 13.3 12.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein TFIIA PF03153.13 GBG86393.1 - 0.093 12.7 15.3 0.099 12.6 15.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1378 PF07125.11 GBG86393.1 - 0.21 11.7 0.4 0.39 10.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Lin-8 PF03353.15 GBG86393.1 - 0.36 10.3 7.1 0.42 10.1 7.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1501 PF07394.12 GBG86393.1 - 0.82 8.7 8.9 0.97 8.4 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) SUIM_assoc PF16619.5 GBG86393.1 - 2.3 8.3 22.8 1.1 9.4 0.2 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPT PF03151.16 GBG86394.1 - 4.1e-08 32.9 8.8 5.5e-08 32.5 8.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GBG86394.1 - 0.0078 16.4 24.0 0.22 11.7 8.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family RRM_1 PF00076.22 GBG86395.1 - 0.0012 18.6 0.4 0.13 12.1 0.1 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 GBG86395.1 - 1.3 7.1 10.1 1.6 6.8 10.1 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 GBG86395.1 - 1.3 8.1 8.1 1.9 7.6 8.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 GBG86395.1 - 1.7 6.8 6.7 2.1 6.5 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG86395.1 - 7.3 6.2 19.6 14 5.3 19.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NUC153 PF08159.12 GBG86396.1 - 2.3e-12 46.5 0.7 2.3e-12 46.5 0.7 2.0 2 0 0 2 2 2 1 NUC153 domain RT_RNaseH_2 PF17919.1 GBG86397.1 - 2.7e-23 81.9 0.0 5.8e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86397.1 - 5.3e-22 78.1 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2779 PF11074.8 GBG86397.1 - 0.07 13.6 0.2 0.19 12.2 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) RT_RNaseH_2 PF17919.1 GBG86399.1 - 2.3e-32 111.0 0.0 4e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86399.1 - 1.7e-29 102.2 0.0 2.9e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86399.1 - 2.3e-12 46.9 0.3 3.7e-12 46.3 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syntaxin-18_N PF10496.9 GBG86399.1 - 0.093 13.0 0.1 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Cobl PF09469.10 GBG86399.1 - 0.094 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain zf-CCHC PF00098.23 GBG86400.1 - 2.6e-05 24.1 1.5 4.4e-05 23.4 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86400.1 - 0.039 13.8 6.5 0.064 13.1 6.5 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF3138 PF11336.8 GBG86401.1 - 0.071 11.7 0.3 0.093 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TPR_MLP1_2 PF07926.12 GBG86401.1 - 0.23 11.5 8.5 0.023 14.8 2.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 GBG86401.1 - 0.58 9.4 10.9 0.19 11.0 3.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 GBG86401.1 - 0.6 9.7 2.7 2 7.9 0.1 2.5 2 1 1 3 3 3 0 fzo-like conserved region AAA_lid_9 PF17871.1 GBG86401.1 - 2.6 8.0 6.1 10 6.1 0.7 2.9 2 1 1 3 3 3 0 AAA lid domain Spc7 PF08317.11 GBG86401.1 - 9 5.1 10.6 2.8 6.7 0.1 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein gag-asp_proteas PF13975.6 GBG86403.1 - 1.2e-06 28.9 0.0 3.3e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86403.1 - 0.00014 22.4 0.0 0.00036 21.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG86403.1 - 0.016 15.0 0.7 0.032 14.0 0.7 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG86403.1 - 0.038 13.7 0.1 0.074 12.8 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.20 GBG86403.1 - 0.097 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG86406.1 - 2.6e-31 107.6 0.0 6.2e-31 106.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86406.1 - 2.1e-28 99.4 0.1 4e-28 98.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86406.1 - 3.5e-27 94.8 0.1 7.6e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86406.1 - 1.9e-19 69.5 0.2 4.5e-19 68.3 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86406.1 - 2.6e-05 24.4 0.0 9e-05 22.7 0.0 1.9 2 0 0 2 2 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG86406.1 - 0.00043 20.5 0.0 0.0014 18.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG86406.1 - 0.0074 16.0 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) Retrotrans_gag PF03732.17 GBG86406.1 - 0.013 15.7 1.2 0.041 14.1 0.1 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG86406.1 - 0.048 13.6 1.4 0.16 11.9 1.4 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG86406.1 - 1.2 9.3 3.6 2.9 8.1 3.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Peptidase_S64 PF08192.11 GBG86406.1 - 1.2 7.5 3.3 2 6.8 3.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Miga PF10265.9 GBG86406.1 - 1.5 7.7 5.8 2.6 6.9 5.8 1.3 1 0 0 1 1 1 0 Mitoguardin Integrase_H2C2 PF17921.1 GBG86407.1 - 6.9e-15 54.9 0.1 1.8e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG86407.1 - 1.6e-07 31.8 0.0 3.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86407.1 - 3.4e-05 24.4 0.0 9.5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG86407.1 - 0.00063 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG86407.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain RVP PF00077.20 GBG86407.1 - 0.039 14.3 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Nop14 PF04147.12 GBG86408.1 - 0.017 13.4 31.3 0.021 13.0 31.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG86408.1 - 0.13 10.3 39.2 0.18 9.9 39.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 GBG86408.1 - 0.14 10.7 31.8 0.21 10.2 31.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GBG86408.1 - 0.73 8.1 28.6 1 7.6 28.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 GBG86408.1 - 1 7.1 7.8 1.4 6.6 7.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SDA1 PF05285.12 GBG86408.1 - 1.1 8.6 37.2 1.7 8.0 37.2 1.2 1 0 0 1 1 1 0 SDA1 Afi1 PF07792.12 GBG86408.1 - 1.7 9.1 9.7 3.1 8.3 9.7 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CPSF100_C PF13299.6 GBG86408.1 - 3.2 7.9 12.2 7.1 6.8 12.2 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 GBG86408.1 - 6.1 6.9 6.4 9.5 6.3 6.4 1.3 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 GBG86408.1 - 6.3 7.2 10.7 13 6.2 10.7 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 GBG86408.1 - 9.9 5.9 23.2 16 5.2 23.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 URO-D PF01208.17 GBG86409.1 - 5.8e-113 377.6 0.0 7.1e-113 377.3 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) NADH-u_ox-rdase PF10785.9 GBG86410.1 - 1.6e-19 70.3 0.1 1.9e-19 70.1 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit RNase_PH PF01138.21 GBG86411.1 - 2.4e-13 50.7 0.8 7.6e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GBG86411.1 - 0.00031 20.7 0.0 0.00065 19.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Flg_bb_rod PF00460.20 GBG86411.1 - 1.9 8.5 8.3 0.6 10.1 4.5 2.0 2 0 0 2 2 2 0 Flagella basal body rod protein Ribosomal_L5e PF17144.4 GBG86412.1 - 2.7e-81 271.3 0.2 4.5e-81 270.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 GBG86412.1 - 3.8e-31 107.9 6.1 3.8e-31 107.9 6.1 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region K_oxygenase PF13434.6 GBG86412.1 - 2.1 7.4 4.4 2.2 7.3 0.8 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF659 PF04937.15 GBG86414.1 - 6.3e-32 110.5 0.2 1.1e-31 109.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG86414.1 - 0.043 13.6 0.1 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region WD40 PF00400.32 GBG86416.1 - 2e-24 85.4 9.4 5.9e-07 30.1 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG86416.1 - 1.1e-06 28.8 0.0 0.79 10.1 0.1 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GBG86416.1 - 0.0081 14.7 0.1 0.015 13.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 GBG86416.1 - 0.11 11.1 0.4 1.3 7.6 0.3 2.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 RNA_pol PF00940.19 GBG86417.1 - 2.5e-156 520.7 0.0 5.8e-156 519.5 0.0 1.6 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 GBG86417.1 - 4e-52 177.7 6.6 4.9e-26 91.9 1.6 2.6 2 0 0 2 2 2 2 DNA-directed RNA polymerase N-terminal SPX PF03105.19 GBG86417.1 - 9 6.1 21.0 0.18 11.7 11.6 2.2 2 0 0 2 2 2 0 SPX domain AKNA PF12443.8 GBG86418.1 - 0.035 14.7 0.1 0.035 14.7 0.1 2.7 3 1 0 3 3 3 0 AT-hook-containing transcription factor Seryl_tRNA_N PF02403.22 GBG86418.1 - 0.041 14.1 1.2 0.041 14.1 1.2 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4250 PF14056.6 GBG86418.1 - 0.23 11.4 0.6 0.87 9.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) DUF1664 PF07889.12 GBG86418.1 - 0.37 10.8 2.3 5.4 7.1 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 GBG86418.1 - 2.7 8.5 6.8 0.72 10.3 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) zf-CCHC PF00098.23 GBG86419.1 - 0.0063 16.5 6.6 0.012 15.6 6.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Hira PF07569.11 GBG86419.1 - 3.4 7.3 7.8 2.9 7.6 3.5 2.2 1 1 1 2 2 2 0 TUP1-like enhancer of split PRP3 PF08572.10 GBG86421.1 - 1.7e-64 217.6 12.1 1.7e-64 217.6 12.1 2.5 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 GBG86421.1 - 1.2e-39 135.7 0.1 1.2e-39 135.7 0.1 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) Collagen PF01391.18 GBG86421.1 - 7.9e-07 28.7 12.8 3.6e-06 26.6 12.8 2.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Myb_DNA-bind_4 PF13837.6 GBG86422.1 - 2e-10 40.9 0.8 4.2e-10 39.9 0.8 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG86422.1 - 0.027 14.8 0.4 0.16 12.3 0.6 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG86423.1 - 3.8e-24 85.2 0.0 7e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Radical_SAM PF04055.21 GBG86423.1 - 4e-24 85.9 0.0 1.3e-15 58.2 0.0 2.6 2 0 0 2 2 2 2 Radical SAM superfamily Plant_tran PF04827.14 GBG86423.1 - 5.1e-10 39.3 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein FAM60A PF15396.6 GBG86424.1 - 3.7 7.5 20.3 5.1 7.0 20.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 GBG86424.1 - 5.5 5.0 28.7 5.8 4.9 28.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.12 GBG86424.1 - 6.8 6.9 16.9 8.1 6.6 16.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Endostatin PF06482.11 GBG86424.1 - 7.8 5.9 15.0 10 5.5 15.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Nop14 PF04147.12 GBG86424.1 - 8.8 4.4 55.8 11 4.1 55.8 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG86424.1 - 9.4 5.6 57.2 12 5.2 57.2 1.2 1 0 0 1 1 1 0 SDA1 RT_RNaseH PF17917.1 GBG86426.1 - 4.3e-27 94.5 0.2 9.5e-27 93.3 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86426.1 - 2.5e-21 75.6 0.1 5.2e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86426.1 - 1e-18 67.1 0.1 2.1e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86426.1 - 5.6e-14 52.4 0.0 1.6e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG86426.1 - 0.00033 20.8 0.0 0.0008 19.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG86426.1 - 0.073 13.4 1.3 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG86426.1 - 0.2 11.7 1.1 0.58 10.2 1.1 1.7 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.11 GBG86426.1 - 0.7 8.1 4.0 1.1 7.5 4.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ecl1 PF12855.7 GBG86426.1 - 6.2 8.0 15.8 1 10.5 5.1 3.2 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins Integrase_H2C2 PF17921.1 GBG86427.1 - 3.3e-14 52.7 0.2 7.3e-14 51.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86427.1 - 0.029 14.6 0.4 0.058 13.6 0.4 1.5 1 0 0 1 1 1 0 H2C2 zinc finger E1-E2_ATPase PF00122.20 GBG86428.1 - 7.8e-44 149.4 0.0 2.1e-43 147.9 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GBG86428.1 - 1.8e-25 90.5 0.4 2e-17 64.2 0.0 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GBG86428.1 - 0.1 12.3 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Retrotrans_gag PF03732.17 GBG86431.1 - 0.01 16.1 0.2 0.027 14.7 0.1 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein TRAUB PF08164.12 GBG86431.1 - 0.16 12.5 1.2 0.3 11.6 0.5 1.8 1 1 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Exo_endo_phos PF03372.23 GBG86432.1 - 6.8e-10 38.9 0.3 1.3e-09 37.9 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dimer_Tnp_hAT PF05699.14 GBG86432.1 - 2.4e-05 24.1 0.4 8.8e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG86432.1 - 0.24 11.4 3.9 1 9.4 3.9 2.2 1 0 0 1 1 1 0 AT hook motif RT_RNaseH_2 PF17919.1 GBG86433.1 - 1.7e-19 69.7 0.0 1.1e-18 67.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86433.1 - 7.3e-11 42.3 0.0 2.3e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HEAT PF02985.22 GBG86433.1 - 2.4e-05 24.2 2.1 0.025 14.8 0.0 3.7 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.23 GBG86433.1 - 0.017 15.1 0.0 0.054 13.5 0.0 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 GBG86433.1 - 0.033 12.8 2.0 0.47 8.9 0.1 2.2 1 1 1 2 2 2 0 Adaptin N terminal region MMS19_N PF14500.6 GBG86433.1 - 0.18 11.4 2.2 0.83 9.2 0.2 2.6 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF4407 PF14362.6 GBG86434.1 - 0.0019 17.6 10.0 0.19 11.1 7.8 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) RT_RNaseH_2 PF17919.1 GBG86436.1 - 4.6e-24 84.4 0.0 8.5e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86436.1 - 4.2e-22 78.4 0.0 8e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86436.1 - 9.2e-10 38.7 0.0 2.7e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG86436.1 - 2.4e-05 24.0 0.0 4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG86437.1 - 1.2e-05 23.7 17.7 1.8e-05 23.2 17.7 1.3 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 GBG86437.1 - 2.9e-05 22.7 26.0 3.8e-05 22.4 26.0 1.1 1 0 0 1 1 1 1 Mpp10 protein SAPS PF04499.15 GBG86437.1 - 0.026 13.3 6.3 0.033 13.0 6.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_polI_A34 PF08208.11 GBG86437.1 - 0.36 10.9 48.6 0.65 10.1 48.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4604 PF15377.6 GBG86437.1 - 1.9 8.9 41.6 1.7 9.0 37.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Nop53 PF07767.11 GBG86437.1 - 2.7 7.3 43.8 5.1 6.4 43.8 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RVT_1 PF00078.27 GBG86438.1 - 8.8e-30 103.9 0.2 3.6e-29 101.9 0.0 2.0 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG86438.1 - 2.7e-09 37.5 0.0 8e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG86438.1 - 4.5e-09 36.2 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG86438.1 - 1.1e-07 32.3 0.0 2.9e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86438.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG86440.1 - 0.0042 17.3 0.0 0.0092 16.2 0.0 1.5 1 1 0 1 1 1 1 Retrotransposon gag protein ICEA PF05315.11 GBG86440.1 - 0.022 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 ICEA Protein IRK_C PF17655.1 GBG86441.1 - 7.5e-28 97.3 0.0 3.7e-27 95.0 0.0 1.9 2 0 0 2 2 2 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 GBG86441.1 - 3.9e-15 55.9 2.5 2.8e-14 53.1 2.5 2.1 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 GBG86441.1 - 0.00033 20.6 7.7 0.00069 19.5 7.7 1.5 1 0 0 1 1 1 1 Ion channel RT_RNaseH_2 PF17919.1 GBG86442.1 - 2.9e-32 110.7 0.0 6.8e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86442.1 - 6.2e-30 103.6 0.0 1.3e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86442.1 - 3.3e-28 98.7 0.1 5.2e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IRK_C PF17655.1 GBG86442.1 - 4.1e-27 94.9 0.0 1.4e-26 93.2 0.0 1.8 2 0 0 2 2 2 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 GBG86442.1 - 2.5e-13 50.0 3.8 1.2e-12 47.8 3.8 2.0 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 GBG86442.1 - 0.0012 18.8 8.1 0.0026 17.7 8.1 1.5 1 0 0 1 1 1 1 Ion channel Oxysterol_BP PF01237.18 GBG86444.1 - 3.1e-40 138.2 0.0 1.7e-25 89.6 0.0 3.2 2 1 0 2 2 2 2 Oxysterol-binding protein Integrase_H2C2 PF17921.1 GBG86444.1 - 9.6e-15 54.4 0.1 2e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG86444.1 - 2.1e-10 40.8 0.1 5.3e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86444.1 - 2.3e-09 37.5 0.0 9.6e-09 35.5 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG86444.1 - 0.0045 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nif11 PF07862.11 GBG86444.1 - 0.012 15.9 0.2 18 5.7 0.0 3.6 3 0 0 3 3 3 0 Nif11 domain Retrotrans_gag PF03732.17 GBG86444.1 - 0.11 12.7 1.8 0.23 11.7 0.1 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Thioredoxin PF00085.20 GBG86445.1 - 1.4e-08 34.6 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin KaiB PF07689.12 GBG86445.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiB domain SET PF00856.28 GBG86446.1 - 2.3e-20 73.7 0.6 2.2e-19 70.5 0.6 2.4 1 1 0 1 1 1 1 SET domain PHD PF00628.29 GBG86446.1 - 4.7e-10 39.2 35.5 1.8e-05 24.5 16.1 4.1 3 0 0 3 3 3 3 PHD-finger AWS PF17907.1 GBG86446.1 - 3.5e-05 23.7 8.3 3.5e-05 23.7 8.3 3.5 5 0 0 5 5 5 1 AWS domain LBR_tudor PF09465.10 GBG86446.1 - 0.0012 18.6 0.2 0.0027 17.5 0.2 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain PHD_2 PF13831.6 GBG86446.1 - 0.005 16.4 5.7 0.005 16.4 5.7 3.6 3 0 0 3 3 3 1 PHD-finger Tudor_3 PF18115.1 GBG86446.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain FIIND PF13553.6 GBG86446.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Function to find SET PF00856.28 GBG86447.1 - 2.1e-20 73.8 0.6 2.1e-19 70.5 0.6 2.4 1 1 0 1 1 1 1 SET domain PHD PF00628.29 GBG86447.1 - 4e-10 39.4 35.5 1.7e-05 24.6 16.1 4.2 3 0 0 3 3 3 3 PHD-finger AWS PF17907.1 GBG86447.1 - 3.4e-05 23.8 8.3 3.4e-05 23.8 8.3 3.6 5 0 0 5 5 5 1 AWS domain LBR_tudor PF09465.10 GBG86447.1 - 0.0011 18.7 0.2 0.0026 17.5 0.2 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain PHD_2 PF13831.6 GBG86447.1 - 0.0048 16.4 5.7 0.0048 16.4 5.7 3.6 3 0 0 3 3 3 1 PHD-finger Tudor_3 PF18115.1 GBG86447.1 - 0.14 12.1 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain FIIND PF13553.6 GBG86447.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Function to find Methyltransf_11 PF08241.12 GBG86448.1 - 9.7e-16 58.2 0.0 2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GBG86448.1 - 1.5e-13 51.2 0.0 3.7e-13 50.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG86448.1 - 2.3e-12 47.0 0.0 4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG86448.1 - 3.1e-10 40.0 0.0 4.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG86448.1 - 7.4e-07 28.7 0.0 1.7e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GBG86448.1 - 7.8e-07 29.8 0.0 1.3e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RT_RNaseH_2 PF17919.1 GBG86449.1 - 2.9e-33 113.9 0.1 5.3e-33 113.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86449.1 - 5.5e-27 94.1 0.3 1e-26 93.2 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86449.1 - 1.3e-18 66.8 0.1 3.7e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86449.1 - 1.1e-15 57.9 0.1 2.6e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG86449.1 - 0.00057 20.1 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG86449.1 - 0.0086 15.8 0.3 0.029 14.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG86450.1 - 1.1e-29 103.5 0.0 1.7e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86450.1 - 5.7e-16 58.4 0.0 2.5e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86450.1 - 6.8e-05 23.1 0.0 0.00019 21.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86450.1 - 0.0094 16.6 0.0 0.021 15.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG86451.1 - 3e-05 23.8 0.0 5.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86451.1 - 0.00098 19.7 0.0 0.0019 18.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86451.1 - 0.0015 19.1 0.0 0.0029 18.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease gag-asp_proteas PF13975.6 GBG86452.1 - 0.001 19.5 0.1 0.0034 17.9 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86452.1 - 0.0041 17.7 0.1 0.015 16.0 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG86452.1 - 0.035 13.9 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG86452.1 - 0.53 10.5 1.9 1.1 9.5 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle DEK_C PF08766.11 GBG86453.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain Myb_DNA-bind_4 PF13837.6 GBG86454.1 - 8.1e-07 29.3 0.9 1.3e-05 25.5 0.2 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Spectrin PF00435.21 GBG86454.1 - 1.5 9.4 3.8 34 5.0 0.1 2.3 2 0 0 2 2 2 0 Spectrin repeat RT_RNaseH_2 PF17919.1 GBG86456.1 - 2.2e-29 101.4 0.0 4.2e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86456.1 - 3.6e-28 98.6 0.0 6.6e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86456.1 - 6.3e-26 90.7 0.1 1.6e-25 89.4 0.1 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG86456.1 - 2.4e-07 30.6 0.0 4.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG86456.1 - 1e-06 28.7 0.1 2.8e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG86456.1 - 2.7e-05 24.7 0.0 6.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86456.1 - 0.00021 21.8 0.0 0.00044 20.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86456.1 - 0.00035 20.4 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Rhamno_transf PF11316.8 GBG86456.1 - 0.04 13.3 0.1 0.097 12.0 0.0 1.7 2 0 0 2 2 2 0 Putative rhamnosyl transferase MFS_1 PF07690.16 GBG86458.1 - 5.2e-15 55.2 30.0 2.7e-08 33.1 11.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GBG86458.1 - 3.1e-11 42.5 10.4 2.3e-10 39.6 0.1 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein OAD_gamma PF04277.13 GBG86458.1 - 0.06 14.0 0.6 0.31 11.7 0.6 2.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Conotoxin PF02950.17 GBG86458.1 - 0.33 12.0 2.6 50 5.0 1.6 2.7 2 0 0 2 2 2 0 Conotoxin Ribosomal_60s PF00428.19 GBG86458.1 - 0.46 11.1 14.4 6.9 7.3 0.6 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein FAM176 PF14851.6 GBG86458.1 - 0.52 10.0 9.0 0.72 9.5 0.0 2.7 1 1 1 2 2 2 0 FAM176 family FAM76 PF16046.5 GBG86458.1 - 1.2 8.4 3.9 7.1 5.9 3.9 1.9 1 1 0 1 1 1 0 FAM76 protein Presenilin PF01080.17 GBG86458.1 - 1.7 7.4 3.4 2.7 6.6 3.4 1.3 1 0 0 1 1 1 0 Presenilin SRP54 PF00448.22 GBG86459.1 - 1.1e-70 237.3 0.1 1.9e-70 236.5 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 GBG86459.1 - 1.9e-28 99.0 1.3 1.9e-28 99.0 1.3 2.8 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 GBG86459.1 - 9.2e-15 54.6 1.0 2.4e-14 53.3 1.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Fe-ADH PF00465.19 GBG86459.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase ResIII PF04851.15 GBG86459.1 - 0.079 12.9 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 GBG86459.1 - 0.086 12.9 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase HAD_2 PF13419.6 GBG86460.1 - 2.7e-18 66.7 0.0 4.6e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.32 GBG86460.1 - 2.3e-17 63.0 0.1 0.0002 22.1 0.0 7.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Hydrolase PF00702.26 GBG86460.1 - 8.6e-12 45.8 0.0 1.5e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG86460.1 - 5.9e-06 26.2 0.0 2.2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like ANAPC4_WD40 PF12894.7 GBG86460.1 - 1.8e-05 24.9 0.0 0.36 11.1 0.0 3.5 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 GBG86460.1 - 0.042 13.1 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Sucrose_synth PF00862.19 GBG86461.1 - 1.1e-199 664.3 0.0 1.5e-100 337.1 0.0 3.1 2 1 1 3 3 3 3 Sucrose synthase Glycos_transf_1 PF00534.20 GBG86461.1 - 1.5e-27 96.2 0.0 2.5e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG86461.1 - 1.3e-09 38.6 0.0 2.8e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG86461.1 - 0.00051 20.4 0.0 0.002 18.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Pox_D5 PF03288.16 GBG86461.1 - 0.12 12.9 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 Poxvirus D5 protein-like Sucrose_synth PF00862.19 GBG86462.1 - 5.8e-40 137.1 0.0 6.7e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Sucrose synthase RVT_1 PF00078.27 GBG86463.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG86463.1 - 0.001 18.3 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Trans_reg_C PF00486.28 GBG86463.1 - 0.026 14.6 0.3 0.046 13.8 0.3 1.3 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal HXXSHH PF07586.11 GBG86463.1 - 0.15 11.7 0.2 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Serpin PF00079.20 GBG86464.1 - 6.6e-93 312.0 0.0 7.9e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DDE_Tnp_4 PF13359.6 GBG86465.1 - 2.7e-21 75.9 0.0 4.2e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86465.1 - 1.5e-13 50.9 0.0 6.8e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Plant transposon protein DUF659 PF04937.15 GBG86466.1 - 3.4e-23 82.2 0.0 5.6e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Serpin PF00079.20 GBG86467.1 - 1.8e-40 139.4 0.0 2.3e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) RT_RNaseH_2 PF17919.1 GBG86468.1 - 5.1e-26 90.6 0.0 9.2e-26 89.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86468.1 - 4.5e-25 88.0 0.0 1e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86468.1 - 4.6e-13 49.2 0.0 2.7e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86468.1 - 6e-05 23.1 0.1 0.00014 21.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Serpin PF00079.20 GBG86472.1 - 6.5e-53 180.4 0.0 2.7e-51 175.0 0.0 2.0 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) DUF2408 PF10303.9 GBG86472.1 - 0.0082 16.7 0.0 10 6.7 0.0 3.3 2 1 0 2 2 2 2 Protein of unknown function (DUF2408) Pheromone PF08015.11 GBG86472.1 - 8.5 7.5 7.6 20 6.3 2.5 2.7 2 0 0 2 2 2 0 Fungal mating-type pheromone TP_methylase PF00590.20 GBG86473.1 - 5.6e-22 78.7 0.0 1.4e-21 77.5 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MukB_hinge PF16330.5 GBG86473.1 - 0.037 13.7 0.1 0.059 13.1 0.1 1.3 1 0 0 1 1 1 0 MukB hinge domain RVT_1 PF00078.27 GBG86474.1 - 2e-29 102.7 0.0 4.3e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 5_3_exonuc_N PF02739.16 GBG86474.1 - 7.1e-27 94.3 0.0 3e-26 92.2 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 GBG86474.1 - 2.5e-15 56.8 0.0 2.5e-15 56.8 0.0 2.8 2 1 1 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold RVP_2 PF08284.11 GBG86474.1 - 3.5e-09 36.5 0.0 6.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86474.1 - 1.6e-07 31.9 0.0 4.3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86474.1 - 3.8e-07 30.6 0.0 1.1e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG86474.1 - 7.9e-06 25.7 0.0 2.8e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Ribosomal_60s PF00428.19 GBG86474.1 - 0.016 15.8 0.6 0.016 15.8 0.6 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein UPF0184 PF03670.13 GBG86474.1 - 0.66 10.4 2.9 0.49 10.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) DAG_kinase_N PF14513.6 GBG86474.1 - 0.67 10.1 3.7 0.4 10.9 0.5 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF4972 PF16342.5 GBG86475.1 - 2.8 7.6 9.5 2.7 7.7 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) DUF4999 PF16390.5 GBG86475.1 - 4.5 7.6 9.2 4.2 7.7 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function MurJ PF03023.14 GBG86476.1 - 5.1e-37 127.5 10.0 6.7e-37 127.1 10.0 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ DUF2070 PF09843.9 GBG86476.1 - 0.45 8.8 7.5 0.62 8.3 7.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MurJ PF03023.14 GBG86477.1 - 6.7e-16 57.9 2.8 6.7e-16 57.9 2.8 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 GBG86477.1 - 2e-08 34.4 11.8 3.5e-08 33.6 11.7 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain PK PF00224.21 GBG86478.1 - 1.5e-155 517.3 1.0 1.5e-155 517.3 1.0 1.4 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG86478.1 - 9.6e-23 80.6 0.8 2.7e-22 79.2 0.3 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GBG86478.1 - 0.0072 15.5 0.4 0.026 13.6 0.2 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PcrB PF01884.17 GBG86478.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 PcrB family Histone PF00125.24 GBG86479.1 - 3.4e-07 30.7 0.8 8.1e-07 29.5 0.8 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 AA_kinase PF00696.28 GBG86480.1 - 4e-05 23.3 0.0 4.1e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 GBG86481.1 - 6.4e-16 57.9 1.8 7.6e-14 51.1 0.5 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family AA_kinase PF00696.28 GBG86481.1 - 0.015 14.9 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 Amino acid kinase family VCBS PF13517.6 GBG86482.1 - 8.1e-08 32.8 1.1 0.049 14.2 0.1 3.8 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GBG86482.1 - 4.6e-06 26.7 7.0 0.014 15.5 0.0 3.9 4 0 0 4 4 4 2 FG-GAP repeat BBS2_Mid PF14783.6 GBG86482.1 - 0.0057 16.7 0.7 0.022 14.8 0.0 2.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Dockerin_1 PF00404.18 GBG86482.1 - 0.029 14.6 0.4 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Dockerin type I domain Itfg2 PF15907.5 GBG86482.1 - 0.058 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 GBG86483.1 - 8.6e-08 32.7 1.1 0.05 14.2 0.1 3.8 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GBG86483.1 - 4.8e-06 26.6 7.0 0.015 15.5 0.0 3.9 4 0 0 4 4 4 2 FG-GAP repeat BBS2_Mid PF14783.6 GBG86483.1 - 0.0059 16.6 0.7 0.023 14.8 0.0 2.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Dockerin_1 PF00404.18 GBG86483.1 - 0.031 14.5 0.4 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Dockerin type I domain Itfg2 PF15907.5 GBG86483.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 RabGAP-TBC PF00566.18 GBG86484.1 - 1.1e-24 87.4 0.1 1.5e-24 86.9 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Romo1 PF10247.9 GBG86485.1 - 5.9e-07 29.8 0.2 5.9e-07 29.8 0.2 2.0 2 0 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 CENP-B_dimeris PF09026.10 GBG86485.1 - 0.0011 19.4 5.6 0.0013 19.1 5.6 1.1 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Tim17 PF02466.19 GBG86485.1 - 0.0014 18.9 0.0 0.0017 18.7 0.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cwf_Cwc_15 PF04889.12 GBG86485.1 - 0.02 14.6 5.0 0.023 14.4 5.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Gly-zipper_Omp PF13488.6 GBG86485.1 - 0.057 13.4 8.1 0.057 13.4 8.1 1.5 2 0 0 2 2 2 0 Glycine zipper TFIIF_alpha PF05793.12 GBG86485.1 - 0.085 11.4 2.6 0.091 11.3 2.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 GBG86485.1 - 0.1 10.7 3.1 0.11 10.6 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 GBG86485.1 - 0.14 11.8 0.5 0.14 11.8 0.5 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 GBG86485.1 - 0.21 10.9 6.5 0.26 10.6 6.5 1.1 1 0 0 1 1 1 0 NOA36 protein Biotin_lipoyl PF00364.22 GBG86486.1 - 2.9e-21 75.0 1.2 3.9e-21 74.7 1.2 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GBG86486.1 - 1.9e-05 24.4 0.0 0.00025 20.8 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like QRPTase_N PF02749.16 GBG86486.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain Maf PF02545.14 GBG86487.1 - 2.7e-33 115.1 0.0 4.7e-33 114.4 0.0 1.4 1 1 0 1 1 1 1 Maf-like protein EFG_IV PF03764.18 GBG86488.1 - 0.032 14.0 0.0 0.089 12.6 0.0 1.7 1 1 1 2 2 2 0 Elongation factor G, domain IV Metallophos PF00149.28 GBG86489.1 - 1.9e-37 129.7 0.2 2.5e-37 129.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GBG86489.1 - 0.0041 17.5 0.4 0.0041 17.5 0.4 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 GBG86489.1 - 0.054 13.7 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain HIT PF01230.23 GBG86490.1 - 6.5e-21 74.9 0.0 9.6e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GBG86490.1 - 3.3e-12 46.9 0.0 5.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 GBG86490.1 - 0.0061 16.4 0.1 0.014 15.2 0.1 1.8 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 AAA PF00004.29 GBG86491.1 - 6e-14 52.6 0.0 8.1e-13 48.9 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 GBG86491.1 - 3.6e-13 49.4 0.0 8.2e-12 45.1 0.0 2.5 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 GBG86491.1 - 8.3e-10 38.4 3.9 1.8e-09 37.3 3.9 1.6 1 0 0 1 1 1 1 PHD-finger AAA_16 PF13191.6 GBG86491.1 - 1.1e-09 39.0 0.1 1.1e-09 39.0 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_lid_10 PF17872.1 GBG86491.1 - 2.4e-08 34.0 0.8 6.4e-08 32.6 0.8 1.6 1 0 0 1 1 1 1 AAA lid domain Cdc6_C PF09079.11 GBG86491.1 - 2.5e-08 33.8 0.0 7.2e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 GBG86491.1 - 3.9e-05 23.9 0.0 0.00012 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain YL1 PF05764.13 GBG86491.1 - 0.0018 18.4 7.1 0.0018 18.4 7.1 4.9 5 0 0 5 5 5 1 YL1 nuclear protein AAA_19 PF13245.6 GBG86491.1 - 0.051 13.9 0.1 0.19 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GBG86491.1 - 0.093 12.5 11.2 0.13 12.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 GBG86491.1 - 0.094 12.6 0.0 0.27 11.2 0.0 1.6 1 1 0 1 1 1 0 NACHT domain PHD_2 PF13831.6 GBG86491.1 - 0.12 12.0 0.4 0.24 11.0 0.4 1.6 1 0 0 1 1 1 0 PHD-finger Dna2 PF08696.11 GBG86492.1 - 1.5e-55 188.2 0.0 2.9e-55 187.2 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 GBG86492.1 - 1.1e-49 168.7 0.0 1.9e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG86492.1 - 5.9e-31 108.2 0.2 1.8e-17 64.0 0.1 3.8 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 GBG86492.1 - 5.2e-13 49.1 0.0 1.1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG86492.1 - 3.8e-12 46.8 0.0 1.8e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GBG86492.1 - 5.4e-06 26.3 0.2 1.5 8.5 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 GBG86492.1 - 4e-05 23.3 0.0 8.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 GBG86492.1 - 0.0051 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 GBG86492.1 - 0.061 13.2 0.9 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SRP54 PF00448.22 GBG86492.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RVT_1 PF00078.27 GBG86493.1 - 3.4e-29 101.9 0.1 6e-29 101.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86493.1 - 1.3e-26 92.6 0.0 5.2e-26 90.6 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86493.1 - 2.8e-25 88.6 0.0 1.4e-24 86.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86493.1 - 9.1e-07 29.4 0.0 2.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG86493.1 - 1.5e-06 28.4 0.0 5.5e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86493.1 - 2.9e-06 27.7 0.0 7.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG86493.1 - 3.1e-06 27.0 0.0 6.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Wtap PF17098.5 GBG86493.1 - 0.048 13.6 0.4 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 WTAP/Mum2p family Asp_protease PF09668.10 GBG86493.1 - 0.055 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease TAF6_C PF07571.13 GBG86494.1 - 5.2e-28 97.2 0.0 8.6e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 GBG86494.1 - 3.1e-27 94.5 0.2 6e-27 93.6 0.2 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 GBG86494.1 - 2.2e-06 28.0 0.1 8.1e-06 26.2 0.1 2.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG86494.1 - 0.019 15.2 0.1 0.042 14.1 0.1 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GBG86494.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Phosphoprotein PF00922.17 GBG86495.1 - 0.015 14.9 12.2 0.015 14.9 12.2 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DUF1997 PF09366.10 GBG86495.1 - 0.015 15.5 2.7 0.018 15.2 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1997) Trypan_PARP PF05887.11 GBG86495.1 - 0.025 14.6 7.4 0.027 14.5 7.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 GBG86495.1 - 0.3 10.7 11.2 0.53 9.8 11.2 1.5 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) CSRNP_N PF16019.5 GBG86495.1 - 0.8 9.6 3.8 0.86 9.5 3.8 1.0 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus AMP-binding_C_2 PF14535.6 GBG86495.1 - 0.84 10.0 6.5 1.5 9.2 6.5 1.5 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Gb3_synth PF04572.12 GBG86496.1 - 1.7e-18 67.1 3.1 1.4e-09 38.2 0.1 2.5 2 0 0 2 2 2 2 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 GBG86496.1 - 9.9e-15 55.0 0.0 2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4042 PF13251.6 GBG86496.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) Ldl_recept_a PF00057.18 GBG86497.1 - 3.8e-09 36.6 22.7 3.1e-08 33.7 12.1 3.2 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A DUF659 PF04937.15 GBG86498.1 - 1.9e-10 40.8 0.0 3.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG86498.1 - 0.018 15.1 7.3 0.054 13.6 7.3 1.9 1 0 0 1 1 1 0 Zinc knuckle Ldl_recept_a PF00057.18 GBG86499.1 - 1.4e-139 454.0 435.9 1.2e-08 35.1 6.8 30.1 30 0 0 30 30 30 28 Low-density lipoprotein receptor domain class A Microvir_lysis PF04517.12 GBG86499.1 - 0.032 14.1 0.7 9.4 6.2 0.1 2.8 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus BTB_3 PF16017.5 GBG86499.1 - 2.1 8.5 4.5 16 5.7 0.6 3.2 2 0 0 2 2 2 0 BTB/POZ domain Ldl_recept_a PF00057.18 GBG86500.1 - 4.8e-59 196.3 193.2 6e-09 36.0 5.7 15.0 15 0 0 15 15 14 13 Low-density lipoprotein receptor domain class A Integrase_H2C2 PF17921.1 GBG86500.1 - 3.8e-20 71.7 0.1 8e-20 70.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG86500.1 - 6.4e-18 65.1 0.9 6.3e-09 35.7 0.1 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG86500.1 - 5e-07 29.6 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG86500.1 - 5.4e-07 29.8 0.0 1.8e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG86500.1 - 4.1e-05 23.5 0.0 0.00028 20.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86500.1 - 0.00079 20.0 0.0 0.0017 19.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG86500.1 - 0.0031 18.1 4.7 0.0047 17.5 0.3 3.1 3 0 0 3 3 2 1 SlyX gag-asp_proteas PF13975.6 GBG86500.1 - 0.0051 17.3 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1515 PF07439.11 GBG86500.1 - 0.016 15.2 0.4 0.042 13.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF2730 PF10805.8 GBG86500.1 - 0.058 13.5 0.6 0.13 12.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF16 PF01519.16 GBG86500.1 - 0.15 12.6 1.2 0.23 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 Retrotrans_gag PF03732.17 GBG86500.1 - 0.51 10.6 1.8 1.2 9.4 0.1 2.5 3 0 0 3 3 3 0 Retrotransposon gag protein PTS_IIA PF02255.16 GBG86500.1 - 1.2 9.2 3.9 2.7 8.1 2.0 2.3 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit RVT_1 PF00078.27 GBG86501.1 - 2.8e-26 92.4 0.6 3.1e-25 89.0 0.0 2.6 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86501.1 - 7.1e-23 80.5 0.0 1.8e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86501.1 - 9.4e-23 80.5 0.0 2.2e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86501.1 - 1.3e-08 35.0 0.0 5.7e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG86501.1 - 2.6e-08 33.7 0.0 5.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86501.1 - 3.3e-08 34.1 0.0 8.5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86501.1 - 4.4e-06 27.2 0.0 1.5e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86501.1 - 0.0018 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG86501.1 - 0.02 15.5 0.8 0.02 15.5 0.8 3.3 5 0 0 5 5 4 0 SlyX Integrase_H2C2 PF17921.1 GBG86501.1 - 1.7 8.8 5.5 4.2 7.6 5.5 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain DUF4510 PF14971.6 GBG86501.1 - 2.1 8.7 8.1 5.9 7.2 8.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) RVT_1 PF00078.27 GBG86502.1 - 1.4e-26 93.4 0.1 1.6e-25 89.9 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86502.1 - 5.3e-23 81.0 0.0 1e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86502.1 - 6.5e-23 81.0 0.0 1.2e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86502.1 - 1e-08 35.3 0.0 3.2e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG86502.1 - 2.5e-08 33.8 0.0 5.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86502.1 - 2.6e-08 34.4 0.0 4.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86502.1 - 4e-06 27.3 0.0 8.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86502.1 - 0.0072 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease APG17 PF04108.12 GBG86502.1 - 0.072 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 Integrase_H2C2 PF17921.1 GBG86502.1 - 1.1 9.4 5.5 2.6 8.2 5.5 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain RVT_1 PF00078.27 GBG86503.1 - 5.5e-23 81.7 0.0 6.7e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ldl_recept_a PF00057.18 GBG86504.1 - 2e-113 370.3 364.5 1.3e-08 34.9 6.0 26.1 25 0 0 25 25 25 24 Low-density lipoprotein receptor domain class A DBD_Tnp_Mut PF03108.15 GBG86504.1 - 8.8e-14 51.2 0.3 4.9e-13 48.9 0.3 2.4 1 0 0 1 1 1 1 MuDR family transposase MULE PF10551.9 GBG86504.1 - 7.2e-10 39.2 0.0 2.1e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain zf-CCHC PF00098.23 GBG86504.1 - 5.6e-05 23.0 3.2 5.6e-05 23.0 3.2 3.5 3 0 0 3 3 3 1 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG86505.1 - 2.3e-24 85.3 0.0 4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86505.1 - 1.3e-22 80.1 0.0 2.2e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LAP1C PF05609.12 GBG86505.1 - 5.5 6.0 6.8 7.6 5.5 6.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 GBG86505.1 - 6.4 6.0 15.0 9 5.5 15.0 1.1 1 0 0 1 1 1 0 BUD22 Pkinase_Tyr PF07714.17 GBG86506.1 - 3.3e-48 164.2 0.0 4.5e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86506.1 - 2.7e-43 148.2 0.0 3.6e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG86506.1 - 0.001 19.0 0.4 0.029 14.3 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Autoind_bind PF03472.15 GBG86506.1 - 0.013 15.0 0.1 0.4 10.1 0.0 2.4 2 0 0 2 2 2 0 Autoinducer binding domain Kinase-like PF14531.6 GBG86506.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 GBG86507.1 - 7.1e-39 133.6 0.0 8.7e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86507.1 - 1.3e-36 126.3 0.0 1.8e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG86507.1 - 0.00025 21.1 0.2 0.55 10.1 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.16 GBG86507.1 - 0.0042 17.2 0.0 0.0079 16.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family DUF2229 PF09989.9 GBG86508.1 - 1 9.0 3.9 1.7 8.3 3.9 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) HisK_sensor PF18698.1 GBG86508.1 - 5.7 7.3 10.2 38 4.7 0.1 2.6 2 1 0 2 2 2 0 Histidine kinase sensor domain Retrotrans_gag PF03732.17 GBG86509.1 - 0.0069 16.6 0.7 0.03 14.6 0.0 2.3 3 0 0 3 3 3 1 Retrotransposon gag protein DUF16 PF01519.16 GBG86509.1 - 0.57 10.7 4.0 0.78 10.3 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 TolA_bind_tri PF16331.5 GBG86509.1 - 2.8 8.1 7.7 3.8 7.6 4.6 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF1957 PF09210.11 GBG86509.1 - 3.7 8.0 7.6 0.84 10.1 3.6 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1957) zf-CCHC PF00098.23 GBG86510.1 - 0.00011 22.2 3.3 0.00024 21.0 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86510.1 - 0.051 13.4 1.2 0.15 12.0 1.2 1.9 1 0 0 1 1 1 0 Zinc knuckle FlxA PF14282.6 GBG86510.1 - 4.6 7.3 8.7 12 6.0 8.7 1.6 1 0 0 1 1 1 0 FlxA-like protein RR_TM4-6 PF06459.12 GBG86510.1 - 9.7 5.9 13.0 3 7.6 8.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RT_RNaseH PF17917.1 GBG86511.1 - 1.4e-13 51.1 0.2 2.4e-13 50.2 0.1 1.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86511.1 - 1.5e-06 28.1 0.0 2.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TFR_dimer PF04253.15 GBG86512.1 - 0.051 13.7 1.9 0.16 12.1 0.5 2.2 2 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain RLL PF10036.9 GBG86512.1 - 0.058 13.2 0.2 0.058 13.2 0.2 1.8 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein Retrotrans_gag PF03732.17 GBG86512.1 - 0.1 12.9 0.5 0.27 11.5 0.5 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4939 PF16297.5 GBG86512.1 - 0.11 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RT_RNaseH PF17917.1 GBG86513.1 - 3.6e-16 59.3 0.3 9.1e-16 58.1 0.3 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86513.1 - 5.3e-09 36.0 0.8 1.9e-08 34.3 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86513.1 - 3.8e-08 33.5 0.1 1e-07 32.2 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG86513.1 - 0.055 13.2 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) CAF1 PF04857.20 GBG86513.1 - 0.12 11.6 3.4 16 4.6 0.0 2.3 2 0 0 2 2 2 0 CAF1 family ribonuclease DUF913 PF06025.12 GBG86513.1 - 0.31 10.0 6.4 0.64 8.9 6.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pox_Ag35 PF03286.14 GBG86513.1 - 2 8.1 19.0 5.4 6.8 19.0 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 GBG86513.1 - 3.3 5.8 31.7 5.9 5.0 31.7 1.4 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 GBG86513.1 - 4 7.6 32.5 9.4 6.4 32.5 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Hid1 PF12722.7 GBG86515.1 - 0.012 13.8 4.0 0.014 13.6 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Prothymosin PF03247.14 GBG86516.1 - 1.4 9.4 14.4 1.2 9.6 8.1 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family CDC45 PF02724.14 GBG86516.1 - 5 5.3 6.3 5.4 5.2 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 GBG86517.1 - 1.4e-58 198.4 0.0 2e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG86517.1 - 6.7e-25 87.9 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-bind_4 PF13837.6 GBG86518.1 - 0.00012 22.3 0.4 0.00025 21.3 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG86518.1 - 0.031 14.5 1.5 0.066 13.4 1.5 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3220 PF11516.8 GBG86518.1 - 0.051 13.8 0.2 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) zf-CCHC PF00098.23 GBG86519.1 - 1.3e-07 31.4 2.9 2.3e-07 30.6 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86519.1 - 0.0023 17.7 2.3 0.0037 17.0 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG86519.1 - 0.0042 16.9 1.1 0.01 15.6 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG86519.1 - 0.092 12.5 0.9 0.17 11.7 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Tau95 PF09734.9 GBG86519.1 - 0.24 12.2 2.5 0.41 11.5 2.5 1.3 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Dimer_Tnp_hAT PF05699.14 GBG86521.1 - 3e-07 30.1 0.1 6.4e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG86522.1 - 3.1e-19 69.4 0.0 5.7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LapA_dom PF06305.11 GBG86524.1 - 0.01 15.6 0.2 0.016 15.0 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Peptidase_M56 PF05569.11 GBG86524.1 - 0.11 11.7 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 TMEM154 PF15102.6 GBG86524.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Integrase_H2C2 PF17921.1 GBG86527.1 - 6.9e-12 45.3 0.0 1.9e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86527.1 - 1e-11 45.1 0.0 2.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86527.1 - 3.7e-11 43.4 0.0 1.5e-07 31.9 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86527.1 - 4e-10 39.5 0.1 1.5e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG86527.1 - 8.7e-09 35.9 0.0 1.6e-05 25.5 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.20 GBG86527.1 - 0.009 16.3 0.0 1 9.7 0.0 2.7 2 0 0 2 2 2 1 Retroviral aspartyl protease rve_3 PF13683.6 GBG86527.1 - 0.07 12.9 0.0 0.24 11.2 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain DNA_pack_N PF02500.15 GBG86527.1 - 0.095 12.5 0.0 0.095 12.5 0.0 1.9 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus DNA_pol_B_N PF18094.1 GBG86527.1 - 1.4 9.5 3.3 1.7 9.2 0.0 3.0 4 0 0 4 4 4 0 DNA polymerase beta N-terminal domain ESSS PF10183.9 GBG86527.1 - 5.7 7.2 5.8 7 6.9 1.5 2.8 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RT_RNaseH_2 PF17919.1 GBG86528.1 - 4.1e-21 74.9 0.0 1.8e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86528.1 - 1.1e-15 57.8 0.0 3.2e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86528.1 - 0.00015 21.3 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG86528.1 - 0.0032 17.2 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease APG17 PF04108.12 GBG86528.1 - 0.031 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Aminotran_3 PF00202.21 GBG86529.1 - 2e-14 53.1 0.1 4.1e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-III Retrotrans_gag PF03732.17 GBG86529.1 - 1.6e-05 25.1 9.5 0.03 14.6 0.3 4.2 4 0 0 4 4 4 2 Retrotransposon gag protein DUF4852 PF16144.5 GBG86529.1 - 0.077 13.1 0.3 0.29 11.3 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) DUF4373 PF14297.6 GBG86529.1 - 0.51 11.2 2.1 1 10.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4373) TFIIA PF03153.13 GBG86529.1 - 1.2 9.0 23.7 0.3 11.0 10.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH_2 PF17919.1 GBG86530.1 - 4.6e-23 81.1 0.0 9.2e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86530.1 - 4.2e-21 75.2 0.0 1.1e-19 70.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86530.1 - 1.3e-10 41.5 0.0 4.2e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86530.1 - 1.9e-06 27.9 0.1 6.1e-06 26.2 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG86530.1 - 0.0002 21.9 0.0 0.0015 19.0 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG86530.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG86530.1 - 0.0019 18.8 0.0 0.0062 17.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease rve_3 PF13683.6 GBG86530.1 - 0.008 15.9 0.0 0.027 14.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG86530.1 - 0.023 14.5 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 GBG86530.1 - 0.045 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG86531.1 - 4.3e-30 104.9 0.1 8.3e-18 64.7 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86531.1 - 1.6e-25 89.4 0.0 4.9e-25 87.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86531.1 - 3.1e-25 88.1 0.0 8.3e-25 86.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86531.1 - 6.3e-14 51.8 0.1 6.3e-14 51.8 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG86531.1 - 9.9e-09 35.7 0.0 4.4e-06 27.2 0.0 2.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86531.1 - 2.4e-06 28.0 0.0 1.1e-05 25.8 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG86531.1 - 4.3e-05 23.3 0.0 0.00015 21.6 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86531.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG86531.1 - 0.0092 16.2 0.1 0.023 14.9 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG86531.1 - 0.013 15.8 1.6 0.036 14.3 0.1 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein BLOC1_2 PF10046.9 GBG86531.1 - 0.58 10.5 3.8 0.67 10.3 1.4 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 GBG86531.1 - 0.75 9.6 3.5 2.7 7.8 0.2 3.1 3 0 0 3 3 3 0 Septum formation initiator Tmemb_cc2 PF10267.9 GBG86531.1 - 1 8.5 5.8 2.2 7.3 5.8 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RT_RNaseH_2 PF17919.1 GBG86532.1 - 3.5e-26 91.2 0.0 8.7e-26 89.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86532.1 - 4.8e-26 91.1 0.0 9.9e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86532.1 - 1.7e-24 86.6 0.0 2.7e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86532.1 - 5.4e-18 64.9 0.5 1.4e-17 63.5 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86532.1 - 1.5e-10 41.3 0.0 4.3e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DIRP PF06584.13 GBG86532.1 - 0.098 12.8 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 DIRP RT_RNaseH PF17917.1 GBG86533.1 - 1.8e-50 169.6 5.5 4.2e-30 104.1 0.3 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86533.1 - 5.2e-48 161.2 1.4 6.3e-35 119.2 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase NAAA-beta PF15508.6 GBG86533.1 - 0.017 15.4 0.1 5.9 7.3 0.0 2.9 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase FAM199X PF15814.5 GBG86533.1 - 6.4 5.7 6.1 11 5.0 6.1 1.3 1 0 0 1 1 1 0 Protein family FAM199X Mcp5_PH PF12814.7 GBG86533.1 - 6.7 6.8 7.1 2 8.5 0.6 2.7 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology zf-CCHC_5 PF14787.6 GBG86535.1 - 0.041 13.6 2.2 0.095 12.4 2.2 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG86535.1 - 2.7 8.2 8.3 0.59 10.3 4.7 1.9 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH PF17917.1 GBG86536.1 - 6e-24 84.3 0.0 1.1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86536.1 - 9.9e-20 70.4 0.0 1.9e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86536.1 - 4.9e-14 52.2 2.1 6.5e-14 51.8 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86536.1 - 3.1e-08 33.8 0.0 6.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG86536.1 - 0.0098 16.1 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG86537.1 - 3.1e-06 27.7 0.0 6.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86537.1 - 0.00029 21.3 0.0 0.00061 20.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF572 PF04502.13 GBG86538.1 - 0.0018 18.0 0.2 0.0024 17.6 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Pep_deformylase PF01327.21 GBG86538.1 - 0.055 13.1 2.7 0.099 12.2 2.7 1.3 1 0 0 1 1 1 0 Polypeptide deformylase Myc_N PF01056.18 GBG86538.1 - 0.072 13.0 2.5 0.12 12.3 2.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Podoplanin PF05808.11 GBG86538.1 - 1.5 8.9 4.4 2.4 8.2 4.4 1.2 1 0 0 1 1 1 0 Podoplanin DUF2868 PF11067.8 GBG86538.1 - 2.4 7.6 5.5 4.6 6.6 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) PhoU PF01895.19 GBG86539.1 - 3.4 8.2 8.3 0.4 11.2 2.6 2.2 2 1 0 2 2 2 0 PhoU domain RT_RNaseH_2 PF17919.1 GBG86540.1 - 8.3e-17 61.1 0.0 2.5e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86540.1 - 1.3e-10 41.2 0.3 3.6e-10 39.8 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86540.1 - 3e-09 37.1 0.1 1.4e-08 34.9 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain RT_RNaseH PF17917.1 GBG86540.1 - 1.9e-08 34.5 0.1 1.2e-07 31.9 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86540.1 - 0.00025 20.6 0.2 0.00045 19.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG86541.1 - 1.8e-29 102.4 0.0 1.4e-28 99.5 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG86541.1 - 1.5e-18 67.2 0.1 2.9e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plant_tran PF04827.14 GBG86541.1 - 1.7e-15 57.2 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Asp_protease_2 PF13650.6 GBG86541.1 - 2.8e-08 34.3 0.0 1.3e-07 32.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86541.1 - 5e-08 33.4 0.0 1.7e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG86541.1 - 8.1e-08 32.1 0.1 2.3e-07 30.7 0.0 1.8 3 0 0 3 3 3 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86541.1 - 0.00041 20.1 0.0 0.00084 19.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DDE_Tnp_1 PF01609.21 GBG86541.1 - 0.0079 15.9 0.0 0.33 10.6 0.0 2.5 2 0 0 2 2 2 1 Transposase DDE domain SAPS PF04499.15 GBG86542.1 - 6.4 5.4 7.1 9.4 4.9 7.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Taxilin PF09728.9 GBG86543.1 - 0.13 11.4 36.1 0.2 10.8 36.1 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein RVT_1 PF00078.27 GBG86544.1 - 8.9e-27 94.0 0.1 1.5e-26 93.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86544.1 - 4.6e-24 84.4 0.0 1.4e-23 82.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86544.1 - 4.9e-23 81.4 0.0 1.3e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86544.1 - 1.6e-06 28.6 0.0 3.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86544.1 - 9.2e-06 26.1 0.0 2.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG86544.1 - 7.7e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86544.1 - 0.00054 19.8 0.0 0.00096 18.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Lys-AminoMut_A PF09043.11 GBG86544.1 - 0.074 11.5 0.4 0.12 10.8 0.4 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit rve PF00665.26 GBG86545.1 - 7.8e-16 58.3 0.0 1.7e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF3592 PF12158.8 GBG86545.1 - 0.15 12.1 0.5 0.25 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) RT_RNaseH_2 PF17919.1 GBG86546.1 - 4.7e-33 113.2 0.0 8.1e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86546.1 - 3.5e-29 101.2 0.2 6.3e-29 100.3 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86546.1 - 3.2e-10 39.9 0.1 6.6e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG86547.1 - 0.075 13.3 0.2 0.23 11.7 0.2 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Fur_reg_FbpB PF13040.6 GBG86547.1 - 0.45 10.1 1.9 1.1 8.9 1.9 1.6 1 0 0 1 1 1 0 Fur-regulated basic protein B RT_RNaseH_2 PF17919.1 GBG86549.1 - 1.2e-31 108.7 0.1 3e-31 107.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86549.1 - 1.1e-28 99.6 0.1 2.9e-28 98.2 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86549.1 - 9.2e-26 90.7 0.1 1.6e-25 89.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86549.1 - 1.4e-14 54.3 0.0 6.2e-14 52.2 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG86549.1 - 0.027 14.8 0.8 0.13 12.6 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF1564 PF07600.11 GBG86549.1 - 0.059 13.1 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) IceA2 PF05862.11 GBG86549.1 - 0.29 11.1 1.2 0.68 9.9 1.2 1.6 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein RVT_1 PF00078.27 GBG86550.1 - 1.8e-29 102.9 0.1 2.7e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86550.1 - 2.6e-22 78.7 0.0 5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86550.1 - 3e-19 68.9 0.1 8.1e-19 67.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG86550.1 - 2e-14 53.8 0.2 2.4e-10 40.6 0.0 2.4 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86550.1 - 0.00066 19.9 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG86550.1 - 0.0032 17.6 0.0 0.0086 16.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG86551.1 - 3.3e-08 33.8 0.1 1e-07 32.2 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86551.1 - 3e-06 26.9 0.0 6.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG86551.1 - 0.00019 21.2 0.0 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG86551.1 - 0.00095 19.4 0.5 0.0036 17.5 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG86551.1 - 0.0016 19.0 0.0 0.035 14.7 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease Chromo PF00385.24 GBG86551.1 - 0.0041 17.0 0.2 0.012 15.5 0.2 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 GBG86551.1 - 0.0058 17.2 0.0 0.063 13.8 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG86551.1 - 0.044 13.8 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase CLZ PF16526.5 GBG86551.1 - 0.11 12.8 2.0 1.1 9.6 0.7 3.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RT_RNaseH_2 PF17919.1 GBG86552.1 - 1.7e-59 198.0 0.4 2.5e-30 104.4 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86552.1 - 1.2e-53 179.8 0.9 1.3e-25 89.7 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86552.1 - 3.7e-32 111.6 0.1 1.3e-28 100.0 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG86552.1 - 7.6e-05 23.2 0.0 0.00028 21.4 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG86552.1 - 0.0031 17.3 0.2 0.0082 15.9 0.0 1.7 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG86552.1 - 0.0071 17.0 0.0 0.026 15.1 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Rab3-GTPase_cat PF13890.6 GBG86552.1 - 0.013 15.1 4.4 1.8 8.2 0.1 3.2 3 0 0 3 3 3 0 Rab3 GTPase-activating protein catalytic subunit zf-CCHC_3 PF13917.6 GBG86552.1 - 0.032 14.2 0.6 0.075 13.0 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle TOBE_2 PF08402.10 GBG86552.1 - 0.076 13.2 0.1 0.86 9.8 0.0 2.8 2 0 0 2 2 2 0 TOBE domain Mcp5_PH PF12814.7 GBG86552.1 - 0.11 12.6 3.1 1.1 9.4 0.1 2.9 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology zf-CCHC PF00098.23 GBG86552.1 - 0.53 10.4 3.8 1.3 9.2 3.8 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF4168 PF13767.6 GBG86552.1 - 0.59 11.3 6.0 8.8 7.6 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) Pex14_N PF04695.13 GBG86552.1 - 1 10.0 7.8 2.7 8.6 2.4 3.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RVT_1 PF00078.27 GBG86553.1 - 3.4e-29 101.9 0.1 4.8e-29 101.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86553.1 - 7.5e-24 83.7 0.0 1.5e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86553.1 - 2e-19 69.8 0.0 3.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2218 PF09981.9 GBG86554.1 - 0.0068 16.8 0.1 0.0079 16.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2218) Glyco_hydro_9 PF00759.19 GBG86555.1 - 1.5e-111 373.8 4.0 1.9e-111 373.5 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM49 PF09478.10 GBG86555.1 - 1.4e-06 28.5 0.6 2.8e-06 27.5 0.6 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 RT_RNaseH PF17917.1 GBG86556.1 - 1.6e-22 79.7 0.0 4e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86556.1 - 2.6e-14 53.0 0.0 4.9e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG86556.1 - 0.32 10.4 7.2 0.44 9.9 7.2 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG86556.1 - 0.65 9.7 9.2 0.96 9.1 9.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG86556.1 - 0.74 8.0 9.7 0.91 7.7 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG86556.1 - 4.5 5.4 8.2 6.2 5.0 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein C2 PF00168.30 GBG86558.1 - 4e-05 23.8 0.0 8.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain tRNA-synt_1e PF01406.19 GBG86559.1 - 1.5e-121 405.4 0.0 2.3e-121 404.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GBG86559.1 - 4.9e-07 28.8 0.1 0.0015 17.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 GBG86559.1 - 0.011 14.7 0.0 0.032 13.1 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain CDC73_N PF16050.5 GBG86559.1 - 0.012 15.0 0.8 0.025 13.9 0.8 1.5 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal tRNA-synt_1 PF00133.22 GBG86559.1 - 0.022 13.0 0.0 0.49 8.6 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (I, L, M and V) LUC7 PF03194.15 GBG86559.1 - 3.2 7.3 8.5 3.6 7.2 0.6 2.6 2 1 0 2 2 2 0 LUC7 N_terminus Vps5 PF09325.10 GBG86559.1 - 5.4 6.5 12.5 12 5.3 0.0 3.6 4 0 0 4 4 4 0 Vps5 C terminal like Atg14 PF10186.9 GBG86559.1 - 5.7 5.9 14.3 1.3 8.1 1.9 2.9 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 PE PF00934.20 GBG86559.1 - 8.2 6.8 9.1 13 6.2 2.6 3.7 4 0 0 4 4 4 0 PE family C2 PF00168.30 GBG86560.1 - 2.1e-05 24.8 0.0 3.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain gag-asp_proteas PF13975.6 GBG86561.1 - 4.1e-06 27.3 0.2 1.6e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86561.1 - 4.9e-05 23.9 0.1 0.00018 22.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG86561.1 - 0.0048 17.1 1.9 0.0048 17.1 1.9 2.5 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 RVP PF00077.20 GBG86561.1 - 0.016 15.5 0.0 0.041 14.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86561.1 - 0.021 14.6 1.7 0.04 13.7 1.7 1.4 1 0 0 1 1 1 0 Aspartyl protease TEX19 PF15553.6 GBG86561.1 - 9.7 6.1 9.1 0.24 11.3 1.2 2.4 2 0 0 2 2 2 0 Testis-expressed protein 19 rve PF00665.26 GBG86562.1 - 4.1e-08 33.4 0.0 2e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86562.1 - 3.4e-06 27.5 0.2 1.4e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86562.1 - 4.3e-05 24.1 0.1 0.00016 22.2 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG86562.1 - 0.014 15.6 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86562.1 - 0.019 14.8 1.7 0.036 13.9 1.7 1.4 1 0 0 1 1 1 0 Aspartyl protease PSII_Pbs27 PF13326.6 GBG86563.1 - 2.9e-30 105.4 0.1 4.4e-30 104.8 0.1 1.4 1 1 0 1 1 1 1 Photosystem II Pbs27 SDA1 PF05285.12 GBG86564.1 - 0.001 18.5 29.4 0.0012 18.3 29.4 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG86564.1 - 0.014 13.7 23.8 0.015 13.6 23.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG86564.1 - 0.035 12.9 19.2 0.039 12.7 19.2 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG86564.1 - 0.3 9.3 27.8 0.35 9.0 27.8 1.1 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 GBG86564.1 - 0.46 9.2 18.7 0.54 9.0 18.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4366 PF14283.6 GBG86564.1 - 6.3 6.8 15.9 0.049 13.7 5.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Raftlin PF15250.6 GBG86564.1 - 7.1 5.3 18.7 9.1 4.9 18.7 1.1 1 0 0 1 1 1 0 Raftlin Chorismate_synt PF01264.21 GBG86565.1 - 7.2e-100 333.9 1.2 4.1e-99 331.4 0.1 2.0 1 1 1 2 2 2 2 Chorismate synthase YgbB PF02542.16 GBG86566.1 - 3.8e-62 209.2 0.0 4.9e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 YgbB family DDE_Tnp_4 PF13359.6 GBG86567.1 - 2.9e-06 27.0 0.0 4.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86567.1 - 3.8e-05 23.4 0.0 5.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG86567.1 - 0.031 14.7 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG86568.1 - 0.0031 17.9 2.7 0.0053 17.1 2.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG86568.1 - 0.055 13.5 1.4 0.1 12.7 1.4 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain SDA1 PF05285.12 GBG86569.1 - 0.0014 18.1 31.8 0.0014 18.1 31.8 3.0 1 1 2 3 3 3 1 SDA1 zf-CCHC PF00098.23 GBG86570.1 - 5.5e-07 29.4 2.7 9.5e-07 28.6 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG86570.1 - 0.11 12.5 0.8 0.29 11.1 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG86570.1 - 0.14 11.9 1.4 0.27 11.0 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86570.1 - 0.26 11.1 3.0 0.45 10.4 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle SH3_15 PF18346.1 GBG86571.1 - 0.023 15.0 4.9 1 9.7 0.5 3.1 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain RVT_1 PF00078.27 GBG86572.1 - 1.1e-20 74.1 0.0 2.4e-20 73.0 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86572.1 - 5e-14 52.1 0.0 1.7e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86572.1 - 0.0037 17.9 0.0 0.012 16.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH PF17917.1 GBG86572.1 - 0.017 15.4 0.2 0.04 14.2 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase HTH_Tnp_Tc5 PF03221.16 GBG86573.1 - 6.8e-10 38.8 0.7 1.5e-09 37.7 0.7 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain RVT_1 PF00078.27 GBG86574.1 - 1.3e-33 116.5 0.2 2.7e-33 115.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86574.1 - 1.3e-30 105.4 0.0 2.9e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86574.1 - 3.1e-27 94.9 0.0 6.6e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CSTF1_dimer PF16699.5 GBG86575.1 - 0.24 11.2 1.6 35 4.3 0.2 3.8 2 0 0 2 2 2 0 Cleavage stimulation factor subunit 1, dimerisation domain Radical_SAM PF04055.21 GBG86576.1 - 1.6e-14 54.6 0.0 2.7e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 GBG86576.1 - 0.0012 19.0 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 GBG86576.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Joubert PF15392.6 GBG86576.1 - 0.3 10.8 3.4 0.56 9.9 3.4 1.4 1 0 0 1 1 1 0 Joubert syndrome-associated DUF3110 PF11360.8 GBG86578.1 - 1.7e-06 28.2 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) RBM1CTR PF08081.11 GBG86578.1 - 0.066 13.3 2.8 0.22 11.6 2.8 1.9 1 0 0 1 1 1 0 RBM1CTR (NUC064) family RT_RNaseH_2 PF17919.1 GBG86579.1 - 1.3e-27 95.7 0.0 2.1e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86579.1 - 2.2e-25 89.0 0.0 3.4e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG86579.1 - 0.71 8.1 9.2 0.94 7.7 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG86579.1 - 4.4 6.6 16.4 6.1 6.2 16.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG86579.1 - 4.9 5.2 17.2 6.7 4.8 17.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG86579.1 - 9.9 5.5 11.7 15 4.9 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RT_RNaseH_2 PF17919.1 GBG86580.1 - 2.1e-24 85.4 0.0 3.5e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86580.1 - 1.3e-20 73.7 0.0 2.2e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG86580.1 - 0.29 9.3 9.2 0.37 8.9 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG86580.1 - 0.85 7.8 10.4 1.2 7.3 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 GBG86580.1 - 0.9 9.8 13.1 1.5 9.1 13.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 GBG86580.1 - 6.2 6.1 12.2 8.6 5.7 12.2 1.1 1 0 0 1 1 1 0 SDA1 PPR PF01535.20 GBG86581.1 - 8.2e-105 336.0 67.5 1.4e-06 28.2 0.1 27.7 29 0 0 29 29 28 22 PPR repeat PPR_2 PF13041.6 GBG86581.1 - 1.8e-97 319.4 17.4 1.9e-11 44.0 0.0 21.3 13 4 10 23 23 23 13 PPR repeat family PPR_3 PF13812.6 GBG86581.1 - 2.6e-73 242.0 0.0 9.7e-09 35.2 0.0 14.0 10 2 2 14 14 14 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG86581.1 - 3.9e-64 212.0 23.7 2.4e-05 23.9 0.0 21.1 24 0 0 24 24 24 12 PPR repeat PPR_long PF17177.4 GBG86581.1 - 3e-32 111.7 0.1 2.1e-05 24.0 0.0 9.7 5 2 6 11 11 11 8 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG86581.1 - 1.1e-05 25.9 13.2 4.2 8.0 0.0 8.8 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG86581.1 - 0.0014 19.3 32.9 81 4.5 0.0 14.5 12 3 3 15 15 15 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG86581.1 - 0.021 15.0 0.5 81 3.8 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG86581.1 - 0.1 12.5 2.4 9.1 6.3 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG86581.1 - 0.12 12.4 9.8 46 4.4 0.0 7.9 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF3933 PF13069.6 GBG86581.1 - 0.14 12.1 0.3 0.42 10.5 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) DUF3368 PF11848.8 GBG86581.1 - 0.47 10.3 11.2 16 5.4 0.0 5.5 7 0 0 7 7 7 0 Domain of unknown function (DUF3368) TPR_2 PF07719.17 GBG86581.1 - 7.3 7.0 10.6 19 5.6 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Oxidored_q6 PF01058.22 GBG86582.1 - 4.2e-23 81.6 0.0 5.9e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DDE_Tnp_4 PF13359.6 GBG86583.1 - 1.3e-23 83.5 0.0 3.3e-22 78.9 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Reticulon PF02453.17 GBG86583.1 - 4.3e-18 65.8 7.0 6.3e-18 65.2 7.0 1.2 1 0 0 1 1 1 1 Reticulon Plant_tran PF04827.14 GBG86583.1 - 1.4e-10 41.1 0.0 2.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein TRAP_alpha PF03896.16 GBG86583.1 - 0.00062 19.1 6.6 0.00096 18.4 6.6 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF2052 PF09747.9 GBG86583.1 - 0.0011 19.1 10.3 0.0018 18.4 10.3 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.14 GBG86583.1 - 0.0024 17.7 6.4 0.0041 17.0 6.4 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein SDA1 PF05285.12 GBG86583.1 - 0.0039 16.7 12.2 0.0053 16.2 12.2 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG86583.1 - 0.03 12.6 15.3 0.04 12.1 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG86583.1 - 0.049 13.0 9.9 0.068 12.5 9.9 1.1 1 0 0 1 1 1 0 BUD22 Zip PF02535.22 GBG86583.1 - 0.23 10.6 1.6 0.42 9.8 1.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Med17 PF10156.9 GBG86583.1 - 0.27 9.9 3.1 0.36 9.5 3.1 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DNA_pol_phi PF04931.13 GBG86583.1 - 0.33 9.0 24.1 0.47 8.5 24.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3391 PF11871.8 GBG86583.1 - 0.47 11.0 5.0 0.85 10.2 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Radial_spoke PF04712.12 GBG86583.1 - 0.54 9.1 19.9 0.78 8.6 19.9 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein SpoIIP PF07454.11 GBG86583.1 - 0.68 9.3 7.5 1 8.8 7.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DAP PF15228.6 GBG86583.1 - 0.69 11.1 3.4 1.3 10.2 3.4 1.4 1 0 0 1 1 1 0 Death-associated protein RPA43_OB PF17875.1 GBG86583.1 - 0.94 10.1 7.2 2.5 8.8 7.2 1.6 2 0 0 2 2 1 0 RPA43 OB domain in RNA Pol I Mpp10 PF04006.12 GBG86583.1 - 1 7.7 20.3 1.4 7.3 20.3 1.1 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 GBG86583.1 - 1 9.1 13.1 1.6 8.5 13.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Prothymosin PF03247.14 GBG86583.1 - 1.2 9.6 34.6 2 8.9 34.6 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family PI3K_1B_p101 PF10486.9 GBG86583.1 - 1.4 6.6 5.4 2 6.1 5.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 GBG86583.1 - 1.6 6.9 16.9 2.4 6.3 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 GBG86583.1 - 1.6 8.9 7.2 2.7 8.1 7.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 GBG86583.1 - 1.8 8.2 12.7 4 7.1 12.7 1.5 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.12 GBG86583.1 - 3.4 6.6 6.0 5.1 6.0 6.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 GBG86583.1 - 3.7 6.8 20.1 2.6 7.3 18.4 1.5 2 0 0 2 2 2 0 NOA36 protein Tim54 PF11711.8 GBG86583.1 - 4.3 6.0 10.4 6.3 5.5 10.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Trypan_PARP PF05887.11 GBG86583.1 - 4.5 7.3 20.5 8.4 6.4 20.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Presenilin PF01080.17 GBG86583.1 - 4.6 5.9 6.5 8 5.1 6.5 1.3 1 0 0 1 1 1 0 Presenilin RNA_polI_A34 PF08208.11 GBG86583.1 - 5.3 7.1 13.3 7.5 6.6 13.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RPN2_C PF18004.1 GBG86583.1 - 5.5 6.9 13.9 8.9 6.2 13.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NARP1 PF12569.8 GBG86583.1 - 6.8 5.5 8.3 10 4.9 8.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CobT PF06213.12 GBG86583.1 - 7.2 5.9 22.3 13 5.1 22.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.11 GBG86583.1 - 8.2 6.4 12.1 15 5.6 12.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop53 PF07767.11 GBG86583.1 - 9.7 5.5 21.0 15 4.8 21.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) N6_N4_Mtase PF01555.18 GBG86584.1 - 6.3e-06 26.1 3.9 8.3e-06 25.7 0.0 3.1 3 0 0 3 3 3 1 DNA methylase UPF0020 PF01170.18 GBG86584.1 - 0.00043 20.0 0.0 0.36 10.5 0.0 3.3 3 0 0 3 3 3 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 GBG86584.1 - 0.027 15.2 0.3 8.1 7.2 0.0 3.6 4 0 0 4 4 4 0 Methyltransferase domain TFIIA PF03153.13 GBG86584.1 - 2.9 7.8 34.8 0.045 13.7 26.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RRN3 PF05327.11 GBG86584.1 - 3.2 6.2 18.1 8.5 4.8 18.1 1.7 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GBG86584.1 - 4 5.5 45.0 0.018 13.3 35.7 1.7 2 0 0 2 2 2 0 Nop14-like family RCC1 PF00415.18 GBG86585.1 - 6.5e-71 234.8 12.6 4.9e-15 55.9 0.3 5.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GBG86585.1 - 3e-39 132.0 24.6 3e-10 39.6 2.4 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 GBG86585.1 - 0.0001 22.8 2.4 2.5 8.6 0.1 3.9 3 1 0 4 4 4 2 SUKH-3 immunity protein DUF4213 PF13938.6 GBG86585.1 - 0.0081 16.4 0.5 1.2 9.4 0.0 2.8 2 1 1 3 3 3 1 Putative heavy-metal chelation RAMA PF18755.1 GBG86585.1 - 0.18 12.3 0.8 1.1 9.7 0.1 2.3 2 1 0 2 2 2 0 Restriction Enzyme Adenine Methylase Associated Cupin_1 PF00190.22 GBG86586.1 - 1.7e-34 118.6 0.0 2.2e-21 76.1 0.1 2.8 3 0 0 3 3 3 2 Cupin Cupin_2 PF07883.11 GBG86586.1 - 0.062 13.0 0.0 0.87 9.3 0.0 2.7 2 0 0 2 2 2 0 Cupin domain LysM PF01476.20 GBG86587.1 - 8.3e-28 96.2 0.0 9.9e-13 47.9 0.0 2.1 2 0 0 2 2 2 2 LysM domain Flagellin_IN PF07196.13 GBG86587.1 - 0.22 11.8 0.5 6.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Flagellin hook IN motif HATPase_c_4 PF13749.6 GBG86588.1 - 0.12 12.6 1.1 47 4.2 0.0 4.0 4 0 0 4 4 4 0 Putative ATP-dependent DNA helicase recG C-terminal AhpC-TSA PF00578.21 GBG86589.1 - 1.5e-15 57.2 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GBG86589.1 - 5.2e-15 55.4 0.0 7.5e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 GBG86589.1 - 0.0013 19.0 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 GBG86589.1 - 0.011 15.8 0.0 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Sigma70_ner PF04546.13 GBG86590.1 - 0.041 13.8 3.3 0.04 13.8 3.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Defensin_int PF17858.1 GBG86590.1 - 0.048 13.6 0.1 0.078 13.0 0.1 1.3 1 0 0 1 1 1 0 Platypus intermediate defensin-like peptide DNA_pol_phi PF04931.13 GBG86590.1 - 2.9 5.9 7.0 3 5.9 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi PMM PF03332.13 GBG86592.1 - 2.7e-109 364.1 0.6 3.2e-109 363.9 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 GBG86592.1 - 5.4e-08 32.9 0.0 1.4e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GBG86592.1 - 0.00066 19.3 0.0 0.52 9.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Presenilin PF01080.17 GBG86593.1 - 0.024 13.4 35.1 0.028 13.2 35.1 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 GBG86593.1 - 0.25 10.3 40.4 0.32 10.0 40.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 GBG86593.1 - 1.5 7.0 35.1 1.7 6.8 35.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dapper PF15268.6 GBG86593.1 - 2.8 6.7 36.0 2.8 6.7 36.0 1.0 1 0 0 1 1 1 0 Dapper SAPS PF04499.15 GBG86593.1 - 5.2 5.7 27.0 5.8 5.6 27.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Membralin PF09746.9 GBG86593.1 - 5.6 5.9 22.7 7.1 5.6 22.7 1.2 1 0 0 1 1 1 0 Tumour-associated protein FAM60A PF15396.6 GBG86593.1 - 8.6 6.3 38.7 13 5.7 38.7 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Asp-B-Hydro_N PF05279.11 GBG86593.1 - 9.9 6.1 33.0 12 5.9 33.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4470 PF14737.6 GBG86594.1 - 4.4e-08 33.2 0.0 1.2e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Beta_helix PF13229.6 GBG86594.1 - 4.3e-07 29.9 0.1 0.015 15.1 0.2 2.3 2 0 0 2 2 2 2 Right handed beta helix region TPR_1 PF00515.28 GBG86594.1 - 0.00098 18.8 0.9 0.56 10.1 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG86594.1 - 0.0064 16.5 0.9 9.9 6.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat RMI1_N PF08585.12 GBG86595.1 - 9.3e-21 74.6 0.0 4e-15 56.2 0.0 3.0 2 0 0 2 2 2 2 RecQ mediated genome instability protein PMT_2 PF13231.6 GBG86596.1 - 1.6e-07 31.7 1.9 1.8e-07 31.5 0.3 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 GBG86596.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Tmemb_170 PF10190.9 GBG86596.1 - 0.21 12.0 2.5 12 6.4 0.8 2.3 2 0 0 2 2 2 0 Putative transmembrane protein 170 RVT_1 PF00078.27 GBG86597.1 - 8.8e-24 84.2 0.1 2.6e-23 82.7 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG86597.1 - 7.3e-08 32.3 0.0 1.8e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86597.1 - 2.1e-05 25.1 0.0 5.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86597.1 - 0.00043 20.8 0.0 0.001 19.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86597.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease eIF-1a PF01176.19 GBG86597.1 - 0.028 14.2 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 CCDC85 PF10226.9 GBG86597.1 - 0.047 13.4 1.8 0.056 13.1 0.1 2.0 2 0 0 2 2 2 0 CCDC85 family HALZ PF02183.18 GBG86597.1 - 0.07 13.4 1.4 0.2 11.9 1.4 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper RVT_1 PF00078.27 GBG86598.1 - 9.2e-31 107.1 0.1 1.9e-30 106.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86598.1 - 4.8e-18 65.0 0.1 1e-17 64.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG86598.1 - 8.9e-18 64.2 0.0 1.9e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86598.1 - 4.1e-14 52.8 0.0 2e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG86598.1 - 1.8e-08 34.6 0.3 3.5e-05 24.0 0.0 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG86598.1 - 6e-07 29.9 0.0 1.6e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG86598.1 - 0.00015 21.5 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86598.1 - 0.00023 21.7 0.0 0.00049 20.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG86598.1 - 0.0028 17.5 0.1 0.0068 16.2 0.0 1.6 2 0 0 2 2 2 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG86598.1 - 0.052 13.8 0.0 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger RRM_1 PF00076.22 GBG86601.1 - 2.7e-18 65.6 0.0 1e-08 34.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GBG86601.1 - 0.0043 16.6 0.0 0.088 12.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.13 GBG86601.1 - 0.043 13.9 19.7 0.025 14.7 10.0 2.2 2 0 0 2 2 2 0 YL1 nuclear protein RRM_occluded PF16842.5 GBG86601.1 - 0.086 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif SR-25 PF10500.9 GBG86601.1 - 1.2 8.7 15.9 0.045 13.4 4.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TMEM247 PF15444.6 GBG86601.1 - 2 8.4 6.1 5.7 6.9 6.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 247 TatD_DNase PF01026.21 GBG86602.1 - 1.1e-39 136.4 0.0 1.4e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DapB_C PF05173.14 GBG86604.1 - 7.8e-17 61.4 0.1 1.6e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 GBG86604.1 - 6e-14 52.2 0.2 1.2e-13 51.3 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DFP PF04127.15 GBG86604.1 - 0.013 15.3 0.1 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein LysM PF01476.20 GBG86605.1 - 4.5e-20 71.4 0.0 8.4e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 LysM domain LysM PF01476.20 GBG86606.1 - 3.4e-19 68.6 0.0 2.9e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 LysM domain DDE_Tnp_4 PF13359.6 GBG86607.1 - 6.5e-22 77.9 3.9 5.6e-21 74.9 0.0 3.0 3 0 0 3 3 3 1 DDE superfamily endonuclease LysM PF01476.20 GBG86607.1 - 2.8e-17 62.5 0.0 1.4e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 LysM domain DUF659 PF04937.15 GBG86607.1 - 8.7e-11 41.9 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Plant_tran PF04827.14 GBG86607.1 - 5.2e-07 29.5 0.0 9.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Dimer_Tnp_hAT PF05699.14 GBG86607.1 - 0.0043 16.8 0.2 0.013 15.2 0.2 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LysM PF01476.20 GBG86608.1 - 5.2e-27 93.6 0.0 1.2e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 LysM domain End3 PF12761.7 GBG86609.1 - 0.0018 18.5 12.0 0.013 15.7 6.7 2.4 1 1 1 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 CENP-F_leu_zip PF10473.9 GBG86609.1 - 0.0019 18.2 14.8 0.0038 17.3 4.8 2.2 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 GBG86609.1 - 0.031 14.5 10.0 0.14 12.4 0.6 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 MapZ_EC1 PF18041.1 GBG86609.1 - 0.048 13.9 1.4 0.89 9.8 0.1 2.5 2 1 0 2 2 2 0 MapZ extracellular domain 1 FlaC_arch PF05377.11 GBG86609.1 - 0.065 13.6 7.0 5.7 7.4 0.1 4.1 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 GBG86609.1 - 0.097 12.9 15.6 0.17 12.1 0.4 4.1 3 1 2 5 5 5 0 Homeobox associated leucine zipper Csm1_N PF18504.1 GBG86609.1 - 0.13 12.6 13.9 18 5.8 0.2 4.2 1 1 3 4 4 4 0 Csm1 N-terminal domain Spc7 PF08317.11 GBG86609.1 - 0.13 11.1 15.7 0.28 10.0 14.2 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein PFO_beta_C PF12367.8 GBG86609.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal DUF5082 PF16888.5 GBG86609.1 - 0.31 11.3 12.3 0.73 10.1 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Cep57_CLD_2 PF14197.6 GBG86609.1 - 0.36 10.9 21.4 0.66 10.1 1.0 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 GBG86609.1 - 0.63 10.6 20.1 0.38 11.3 3.4 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 GBG86609.1 - 0.68 10.3 15.5 0.23 11.9 0.9 2.1 1 1 0 2 2 2 0 Fez1 MCU PF04678.13 GBG86609.1 - 1.4 9.0 5.1 9.5 6.3 1.1 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter ZapB PF06005.12 GBG86609.1 - 1.8 9.0 20.7 0.68 10.4 2.5 4.1 2 2 0 2 2 2 0 Cell division protein ZapB PRKG1_interact PF15898.5 GBG86609.1 - 1.8 9.5 16.7 12 6.9 9.5 2.5 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain OrfB_IS605 PF01385.19 GBG86609.1 - 2.1 8.6 5.2 8.5 6.6 1.5 2.6 3 0 0 3 3 3 0 Probable transposase DUF1640 PF07798.11 GBG86609.1 - 2.2 8.3 14.6 0.66 10.0 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Med9 PF07544.13 GBG86609.1 - 2.8 8.1 6.6 5.2 7.2 3.3 2.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 GBG86609.1 - 3.2 7.6 17.8 1.1 9.0 0.5 4.1 1 1 2 3 3 3 0 Septum formation initiator Phlebovirus_NSM PF07246.11 GBG86609.1 - 5.1 6.4 10.0 6.5 6.1 4.9 2.0 1 1 2 3 3 3 0 Phlebovirus nonstructural protein NS-M Spc24 PF08286.11 GBG86609.1 - 7.2 6.9 14.1 18 5.6 0.4 3.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 UPF0242 PF06785.11 GBG86609.1 - 8.4 6.4 13.3 4.6e+02 0.8 13.4 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus eIF3_subunit PF08597.10 GBG86610.1 - 2.2e-45 155.5 15.2 2.6e-45 155.2 15.2 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit FERM_f0 PF16511.5 GBG86611.1 - 0.45 10.8 8.2 15 6.0 0.5 3.6 1 1 3 4 4 4 0 N-terminal or F0 domain of Talin-head FERM Pantoate_ligase PF02569.15 GBG86612.1 - 5.8e-88 294.5 0.0 4.4e-87 291.7 0.0 1.9 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase PRD PF00874.20 GBG86613.1 - 0.051 13.9 0.2 0.094 13.0 0.2 1.3 1 0 0 1 1 1 0 PRD domain PIG-F PF06699.11 GBG86614.1 - 4.5e-35 121.4 12.8 5.4e-35 121.2 12.8 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F RT_RNaseH_2 PF17919.1 GBG86615.1 - 1e-27 96.1 0.0 3.1e-27 94.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86615.1 - 1.1e-25 90.0 0.0 2.4e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86615.1 - 3.2e-18 65.6 0.6 7.1e-18 64.5 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG86615.1 - 2e-15 56.9 0.0 4.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86615.1 - 0.0033 17.6 0.0 0.0098 16.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG86615.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger PNMA PF14893.6 GBG86615.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 PNMA NAP PF00956.18 GBG86617.1 - 2.6e-31 108.8 5.9 2.5e-29 102.3 5.9 3.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) RRP7 PF12923.7 GBG86617.1 - 0.084 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF3135 PF11333.8 GBG86617.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) INCA1 PF15142.6 GBG86617.1 - 0.14 12.2 0.1 10 6.1 0.1 2.3 2 0 0 2 2 2 0 INCA1 Myb_DNA-bind_4 PF13837.6 GBG86618.1 - 1.9e-06 28.2 1.7 2.6e-06 27.7 0.6 1.8 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG86618.1 - 0.0031 17.5 0.9 0.0084 16.2 0.1 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain CAP_N PF01213.19 GBG86618.1 - 0.057 12.9 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2057 PF09829.9 GBG86618.1 - 0.074 13.2 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Reticulon PF02453.17 GBG86619.1 - 5.4e-31 107.7 9.9 7.5e-31 107.2 9.9 1.2 1 0 0 1 1 1 1 Reticulon DAGK_prokar PF01219.19 GBG86619.1 - 0.054 13.3 0.1 0.054 13.3 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Reticulon PF02453.17 GBG86620.1 - 2.8e-31 108.6 9.9 3.8e-31 108.2 9.9 1.2 1 0 0 1 1 1 1 Reticulon DAGK_prokar PF01219.19 GBG86620.1 - 0.042 13.7 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Reticulon PF02453.17 GBG86621.1 - 9.6e-29 100.4 11.7 1.3e-28 99.9 11.7 1.2 1 0 0 1 1 1 1 Reticulon DAGK_prokar PF01219.19 GBG86621.1 - 0.022 14.6 5.7 0.038 13.8 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Babuvirus_MP PF07234.11 GBG86621.1 - 0.21 11.8 2.9 2.1 8.5 0.1 2.3 2 0 0 2 2 2 0 Movement and RNA silencing protein Reticulon PF02453.17 GBG86622.1 - 3.2e-31 108.4 9.9 4.7e-31 107.9 9.9 1.3 1 0 0 1 1 1 1 Reticulon DAGK_prokar PF01219.19 GBG86622.1 - 0.049 13.5 0.0 0.049 13.5 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Mannosyl_trans PF05007.13 GBG86623.1 - 7.1e-74 248.9 30.4 4.9e-59 200.3 17.5 2.9 3 0 0 3 3 3 2 Mannosyltransferase (PIG-M) PIG-U PF06728.13 GBG86623.1 - 7.9e-12 44.9 1.2 7.9e-12 44.9 1.2 2.3 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 GBG86623.1 - 1.1e-05 25.2 11.5 1.1e-05 25.2 11.5 3.8 3 1 0 4 4 4 2 Glycosyltransferase family 87 DUF5520 PF17658.1 GBG86623.1 - 0.47 9.5 5.7 0.8 8.8 5.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5520) DUF2956 PF11169.8 GBG86623.1 - 1.4 9.1 4.7 74 3.6 4.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RRM_1 PF00076.22 GBG86624.1 - 8.4e-49 163.3 0.1 4.1e-17 61.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG86624.1 - 5.8e-13 48.8 0.0 0.0012 19.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 GBG86624.1 - 1.6e-09 37.6 0.1 0.00068 19.6 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 GBG86624.1 - 0.00023 21.4 0.0 8.5 6.6 0.0 4.3 3 2 2 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter DUF4651 PF15513.6 GBG86624.1 - 0.0027 17.5 0.1 0.8 9.6 0.0 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4651) RL PF17797.1 GBG86624.1 - 0.0065 16.4 0.0 3.7 7.5 0.0 3.3 3 0 0 3 3 3 1 RL domain PDZ PF00595.24 GBG86625.1 - 5.9e-07 29.7 0.2 1.5e-06 28.5 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GBG86625.1 - 8e-06 26.1 0.1 1.7e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GBG86625.1 - 3.8e-05 23.4 0.2 8.7e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 PDZ domain DUF659 PF04937.15 GBG86626.1 - 5.9e-16 58.7 0.0 8.4e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Zn-ribbon_8 PF09723.10 GBG86627.1 - 0.00054 20.0 0.8 0.00095 19.2 0.8 1.3 1 0 0 1 1 1 1 Zinc ribbon domain HypA PF01155.19 GBG86627.1 - 0.00058 19.9 0.5 0.00073 19.5 0.5 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin PF00301.20 GBG86627.1 - 0.0013 18.7 12.9 0.02 14.9 8.9 2.8 2 1 0 2 2 2 1 Rubredoxin CxC4 PF18717.1 GBG86627.1 - 0.065 13.1 0.6 0.08 12.8 0.6 1.2 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases TF_Zn_Ribbon PF08271.12 GBG86627.1 - 0.11 12.0 2.5 7.5 6.2 0.4 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_11 PF16622.5 GBG86627.1 - 0.22 11.3 1.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-HIT PF04438.16 GBG86627.1 - 0.66 9.9 6.5 0.24 11.3 0.8 2.2 2 0 0 2 2 2 0 HIT zinc finger UPF0547 PF10571.9 GBG86627.1 - 0.74 9.9 6.2 10 6.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RT_RNaseH_2 PF17919.1 GBG86630.1 - 2.6e-22 78.7 0.0 5.9e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86630.1 - 1.5e-20 73.5 0.0 1e-19 70.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86630.1 - 2.7e-09 37.2 0.0 6.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86630.1 - 0.00027 21.4 0.0 0.00077 20.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86630.1 - 0.0007 20.2 0.0 0.0021 18.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG86630.1 - 0.0057 16.9 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86630.1 - 0.0083 15.9 0.1 0.026 14.3 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG86630.1 - 0.046 14.0 0.1 0.2 11.9 0.0 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein Pkinase PF00069.25 GBG86631.1 - 8.1e-63 212.2 0.0 1.2e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG86631.1 - 1e-24 87.2 0.0 4.6e-24 85.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 GBG86631.1 - 3.2e-10 38.8 1.3 3.3e-08 32.5 0.4 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GBG86631.1 - 3e-08 33.0 1.1 5.9e-05 22.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GBG86631.1 - 5e-07 30.1 1.4 1.6e-06 28.5 1.4 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 GBG86631.1 - 7.2e-06 25.8 4.7 8.2e-06 25.6 2.8 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 GBG86631.1 - 2e-05 23.9 0.2 4.8e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 EF hand Kdo PF06293.14 GBG86631.1 - 2.1e-05 24.0 0.0 4.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 GBG86631.1 - 0.0023 17.9 0.2 0.0046 16.9 0.2 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.6 GBG86631.1 - 0.0032 16.8 1.1 0.05 12.9 0.1 3.0 2 1 0 3 3 3 1 Kinase-like APH PF01636.23 GBG86631.1 - 0.012 15.6 1.1 1.1 9.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family EF-hand_14 PF17959.1 GBG86631.1 - 0.023 15.0 0.4 11 6.5 0.1 3.0 2 1 0 2 2 2 0 EF-hand domain RT_RNaseH_2 PF17919.1 GBG86633.1 - 1.1e-13 51.0 0.0 2.9e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86633.1 - 2e-10 40.6 0.0 3.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG86633.1 - 2.8e-08 34.2 0.0 5.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86633.1 - 9.7e-05 22.9 0.0 0.00018 22.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG86633.1 - 0.0076 16.5 0.0 0.022 15.1 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86633.1 - 0.056 13.2 0.5 0.1 12.4 0.5 1.4 1 0 0 1 1 1 0 Aspartyl protease PTPRCAP PF15713.5 GBG86633.1 - 0.16 12.3 8.5 0.27 11.5 8.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RT_RNaseH PF17917.1 GBG86633.1 - 0.19 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase PGA2 PF07543.12 GBG86633.1 - 2.3 8.2 13.0 3.9 7.5 13.0 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 FAM176 PF14851.6 GBG86633.1 - 8.8 6.0 7.9 16 5.2 7.9 1.3 1 0 0 1 1 1 0 FAM176 family Nup54 PF13874.6 GBG86634.1 - 0.79 9.8 8.1 1.2 9.2 8.1 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 XhlA PF10779.9 GBG86634.1 - 1.5 9.1 3.8 4.2 7.6 3.8 1.8 1 0 0 1 1 1 0 Haemolysin XhlA DUF4140 PF13600.6 GBG86634.1 - 5.7 7.5 9.7 2.4e+02 2.3 9.7 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Sugar_tr PF00083.24 GBG86635.1 - 7.2e-72 242.7 18.0 7.3e-40 137.2 0.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GBG86635.1 - 1.4e-20 73.5 36.4 1.4e-17 63.7 8.8 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 GBG86635.1 - 0.28 11.7 0.1 0.28 11.7 0.1 2.9 3 0 0 3 3 3 0 Phage holin family 2 rve PF00665.26 GBG86637.1 - 4.5e-11 43.0 0.0 8.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86637.1 - 0.0013 19.3 0.0 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86637.1 - 0.0021 18.6 0.0 0.0047 17.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 GBG86637.1 - 0.0079 16.0 0.0 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVP PF00077.20 GBG86637.1 - 0.016 15.5 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Fur_reg_FbpB PF13040.6 GBG86637.1 - 0.17 11.4 1.0 0.38 10.3 1.0 1.5 1 0 0 1 1 1 0 Fur-regulated basic protein B GTP1_OBG PF01018.22 GBG86639.1 - 0.068 12.8 2.2 1.9 8.1 1.1 2.4 2 0 0 2 2 2 0 GTP1/OBG Cwf_Cwc_15 PF04889.12 GBG86640.1 - 0.19 11.5 15.9 0.28 10.9 15.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PARG_cat PF05028.14 GBG86641.1 - 9.9e-113 376.8 0.0 6.8e-112 374.1 0.0 2.2 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) RT_RNaseH_2 PF17919.1 GBG86641.1 - 5.4e-23 80.9 0.0 1.3e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86641.1 - 3.8e-21 75.4 0.0 7.6e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86641.1 - 1.3e-07 32.1 0.0 4.5e-07 30.4 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG86641.1 - 5.6e-07 29.4 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG86641.1 - 3.7e-06 27.4 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86641.1 - 0.018 14.9 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG86641.1 - 0.025 14.9 0.0 0.072 13.4 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein PARG_cat PF05028.14 GBG86642.1 - 9e-102 340.8 0.0 7.3e-101 337.8 0.0 2.2 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) RT_RNaseH_2 PF17919.1 GBG86642.1 - 5.4e-23 80.9 0.0 1.2e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86642.1 - 3.7e-21 75.4 0.0 7.3e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86642.1 - 1.2e-07 32.2 0.0 4.4e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG86642.1 - 5.3e-07 29.5 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG86642.1 - 3.7e-06 27.4 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86642.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG86642.1 - 0.024 14.9 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 GBG86643.1 - 2.1e-05 24.7 3.8 0.00086 19.5 0.0 3.6 3 1 0 3 3 3 2 Retrotransposon gag protein Use1 PF09753.9 GBG86643.1 - 0.89 9.2 11.4 0.98 9.1 10.0 1.8 2 0 0 2 2 2 0 Membrane fusion protein Use1 RT_RNaseH_2 PF17919.1 GBG86644.1 - 5.5e-25 87.3 0.0 1.3e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86644.1 - 1.8e-23 82.8 0.0 3.9e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86644.1 - 3.9e-12 46.2 0.0 1.3e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG86644.1 - 0.00052 20.2 3.9 0.0011 19.2 0.0 3.5 6 0 0 6 6 6 1 Retrotransposon gag protein ST7 PF04184.12 GBG86644.1 - 0.1 11.0 0.3 2.1 6.7 0.1 2.0 2 0 0 2 2 2 0 ST7 protein SCAI PF12070.8 GBG86645.1 - 1.6e-173 578.5 0.0 9.2e-173 575.9 0.0 1.9 1 1 0 1 1 1 1 Protein SCAI SNARE_assoc PF09335.11 GBG86646.1 - 9.8e-07 29.3 2.9 3.5e-06 27.5 0.5 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein LapA_dom PF06305.11 GBG86646.1 - 0.0034 17.2 0.3 0.0034 17.2 0.3 2.8 3 0 0 3 3 3 1 Lipopolysaccharide assembly protein A domain HR1 PF02185.16 GBG86646.1 - 0.43 10.7 8.2 1.8 8.7 2.7 2.3 2 0 0 2 2 2 0 Hr1 repeat gag-asp_proteas PF13975.6 GBG86648.1 - 5.6e-05 23.6 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86648.1 - 0.0048 17.5 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG86648.1 - 0.033 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG86648.1 - 0.049 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG86648.1 - 5.5 7.2 4.9 1.4 9.2 1.7 1.7 2 0 0 2 2 2 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG86648.1 - 6.5 6.5 6.7 0.51 10.1 0.2 2.5 3 0 0 3 3 3 0 Topoisomerase I zinc-ribbon-like Myb_DNA-bind_4 PF13837.6 GBG86649.1 - 6.7e-08 32.8 0.3 6.6e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG86649.1 - 0.0031 17.6 0.3 0.0031 17.6 0.3 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain NAD_Gly3P_dh_C PF07479.14 GBG86650.1 - 2.7e-21 76.3 0.0 5e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 GBG86650.1 - 7.7e-11 42.2 0.0 7.9e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus BUD22 PF09073.10 GBG86651.1 - 0.12 11.7 28.3 0.19 11.0 28.3 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG86651.1 - 0.29 9.3 25.6 0.37 9.0 25.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG86651.1 - 0.93 8.9 30.7 1.3 8.4 30.7 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG86651.1 - 1.1 8.8 14.5 1.5 8.3 14.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 GBG86651.1 - 1.1 7.5 20.5 1.4 7.2 20.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG86651.1 - 2.3 6.7 25.2 3 6.3 25.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Coilin_N PF15862.5 GBG86651.1 - 4.3 7.1 8.4 8.2 6.2 8.4 1.5 1 0 0 1 1 1 0 Coilin N-terminus PPL5 PF18168.1 GBG86651.1 - 8.3 5.6 10.4 13 4.9 10.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 LAP1C PF05609.12 GBG86651.1 - 8.7 5.3 13.8 11 5.0 13.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Sucrose_synth PF00862.19 GBG86653.1 - 2.4e-254 844.8 0.0 2.9e-254 844.5 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG86653.1 - 1.6e-28 99.4 0.0 2.7e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG86653.1 - 2.7e-10 40.8 0.0 6.9e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG86653.1 - 8.8e-05 22.8 0.0 0.00026 21.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pox_D5 PF03288.16 GBG86653.1 - 0.046 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like Integrase_H2C2 PF17921.1 GBG86654.1 - 4.5e-15 55.5 0.1 1.1e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86654.1 - 0.00014 22.0 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG86654.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Angiomotin_C PF12240.8 GBG86654.1 - 0.065 12.8 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Angiomotin C terminal GIY-YIG PF01541.24 GBG86655.1 - 1.3e-05 25.4 0.1 5.1e-05 23.5 0.1 2.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain Methyltr_RsmB-F PF01189.17 GBG86656.1 - 1.3e-17 64.1 0.5 2.5e-17 63.2 0.1 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 GBG86656.1 - 1.2e-06 29.1 0.6 1e-05 26.1 0.1 2.4 3 0 0 3 3 3 1 Methyltransferase domain RrnaAD PF00398.20 GBG86656.1 - 3.2e-05 23.1 0.0 6.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 GBG86656.1 - 0.00095 19.3 0.0 0.009 16.1 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 GBG86656.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG86656.1 - 0.0042 16.5 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltr_RsmF_N PF17125.5 GBG86656.1 - 0.22 12.0 0.0 0.41 11.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltr_RsmB-F PF01189.17 GBG86657.1 - 8.4e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Myb_DNA-bind_4 PF13837.6 GBG86658.1 - 3.2e-10 40.2 0.3 5.9e-10 39.4 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG86658.1 - 0.0068 16.7 0.2 0.018 15.4 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG86658.1 - 0.046 13.8 1.0 0.1 12.7 1.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG86660.1 - 2.4e-32 111.0 0.1 4.5e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86660.1 - 7.5e-28 96.9 0.0 1.4e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86660.1 - 1.4e-20 73.8 0.0 2.2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86660.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain ATP-synt_ab PF00006.25 GBG86661.1 - 1.6e-60 204.4 0.0 2.3e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GBG86661.1 - 9.3e-22 77.3 1.6 1.9e-21 76.3 1.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 GBG86661.1 - 0.058 12.6 1.3 0.064 12.4 0.2 1.5 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 GBG86661.1 - 0.059 13.3 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 GBG86661.1 - 0.11 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 GBG86661.1 - 0.16 11.9 0.1 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase RPW8 PF05659.11 GBG86662.1 - 8.9e-07 28.7 4.5 9.9e-07 28.5 2.7 1.9 1 1 1 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF948 PF06103.11 GBG86662.1 - 0.065 13.5 0.9 7.4 6.9 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RVT_1 PF00078.27 GBG86664.1 - 4.3e-33 114.7 0.1 8.5e-33 113.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86664.1 - 1.6e-29 101.9 0.0 3.1e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86664.1 - 1.3e-26 92.9 0.1 2.9e-26 91.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86664.1 - 5.1e-15 55.7 0.0 1.3e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86664.1 - 1.6e-14 53.8 0.1 2.4e-13 50.0 0.1 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG86664.1 - 3.5e-08 33.3 0.0 7.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86664.1 - 0.00032 20.5 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG86664.1 - 0.00043 20.9 0.0 0.0058 17.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86664.1 - 0.0007 20.1 0.0 0.0019 18.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG86664.1 - 0.072 13.3 0.0 0.29 11.4 0.0 2.1 2 0 0 2 2 1 0 H2C2 zinc finger Rhamno_transf PF11316.8 GBG86664.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase Fascin PF06268.13 GBG86664.1 - 0.14 12.4 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Fascin domain gag-asp_proteas PF13975.6 GBG86665.1 - 2.5e-07 31.1 0.0 7.1e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86665.1 - 8.7e-05 23.1 0.1 0.00034 21.2 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG86665.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86665.1 - 0.014 15.1 1.1 0.027 14.3 1.1 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG86666.1 - 1.4e-19 70.4 0.0 2.2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG86666.1 - 0.0035 17.1 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LAT PF15234.6 GBG86667.1 - 0.054 13.2 1.7 0.097 12.4 1.7 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells Serinc PF03348.15 GBG86667.1 - 0.18 10.7 0.2 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) zf-CCHC PF00098.23 GBG86669.1 - 1.3e-05 25.1 4.8 2.4e-05 24.2 4.8 1.4 1 0 0 1 1 1 1 Zinc knuckle PIN_4 PF13638.6 GBG86669.1 - 0.047 14.0 0.5 0.047 14.0 0.5 2.1 1 1 1 2 2 2 0 PIN domain zf-CCHC_6 PF15288.6 GBG86669.1 - 0.24 11.3 2.8 0.26 11.2 0.9 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86669.1 - 0.77 9.6 8.0 0.19 11.5 4.9 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG86670.1 - 0.68 10.1 3.6 1.3 9.3 3.6 1.4 1 0 0 1 1 1 0 Zinc knuckle BBS1 PF14779.6 GBG86670.1 - 0.83 9.0 4.7 1.1 8.6 4.7 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 PIN_4 PF13638.6 GBG86670.1 - 4.3 7.6 11.2 0.063 13.6 0.8 2.2 1 1 1 2 2 2 0 PIN domain PTP_tm PF18861.1 GBG86671.1 - 4.6e-05 23.5 0.1 7.3e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DEK_C PF08766.11 GBG86672.1 - 0.0089 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain zf-CCHC PF00098.23 GBG86673.1 - 0.016 15.3 5.1 0.035 14.2 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG86673.1 - 0.17 11.6 1.3 0.38 10.5 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3584 PF12128.8 GBG86673.1 - 5.2 4.4 19.5 7.3 4.0 19.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SLC12 PF03522.15 GBG86675.1 - 1.2 8.1 2.8 1.3 8.0 2.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Pkinase_Tyr PF07714.17 GBG86676.1 - 1.5e-44 152.3 0.0 2.7e-44 151.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86676.1 - 2.1e-43 148.6 0.0 3e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG86676.1 - 0.0015 18.5 0.1 0.011 15.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 GBG86676.1 - 0.2 11.9 0.0 0.49 10.6 0.0 1.6 2 0 0 2 2 2 0 ABC1 family DnaJ_C PF01556.18 GBG86677.1 - 0.017 15.2 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 DnaJ C terminal domain KNOX2 PF03791.13 GBG86677.1 - 0.027 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 KNOX2 domain API5 PF05918.11 GBG86677.1 - 0.17 10.6 4.0 0.21 10.3 4.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GRP PF07172.11 GBG86677.1 - 2.2 9.0 22.0 1.6 9.5 18.6 2.0 2 0 0 2 2 2 0 Glycine rich protein family gag-asp_proteas PF13975.6 GBG86678.1 - 0.019 15.5 0.0 0.053 14.1 0.0 1.7 2 0 0 2 2 1 0 gag-polyprotein putative aspartyl protease Spc29 PF17082.5 GBG86678.1 - 0.059 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Spindle Pole Component 29 Asp_protease_2 PF13650.6 GBG86678.1 - 0.075 13.7 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease ADIP PF11559.8 GBG86678.1 - 0.076 13.1 0.6 0.13 12.4 0.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Asp_protease PF09668.10 GBG86678.1 - 0.081 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease TolA_bind_tri PF16331.5 GBG86678.1 - 0.1 12.7 4.7 0.05 13.7 1.2 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF4806 PF16064.5 GBG86678.1 - 0.11 12.8 0.2 0.37 11.1 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4806) Sec34 PF04136.15 GBG86678.1 - 0.13 12.1 0.7 0.26 11.2 0.7 1.4 1 0 0 1 1 1 0 Sec34-like family DUF16 PF01519.16 GBG86678.1 - 0.32 11.5 2.4 0.4 11.2 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 GBG86678.1 - 0.43 11.2 7.4 0.1 13.3 3.0 2.1 1 1 1 2 2 2 0 SlyX Trimer_CC PF08954.11 GBG86678.1 - 0.56 9.8 1.5 7.2 6.3 0.1 2.6 1 1 1 2 2 2 0 Trimerisation motif Glyoxalase_4 PF13669.6 GBG86679.1 - 6.7e-06 26.3 0.2 0.017 15.4 0.0 2.9 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 GBG86679.1 - 1.3e-05 25.4 0.2 0.00011 22.4 0.0 2.3 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 GBG86679.1 - 2.4e-05 24.5 0.2 0.0036 17.5 0.0 3.2 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 GBG86679.1 - 0.03 14.4 0.1 0.67 10.1 0.1 2.6 1 1 0 1 1 1 0 Glyoxalase-like domain Dala_Dala_lig_C PF07478.13 GBG86680.1 - 2.5e-18 66.3 0.0 4.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.28 GBG86680.1 - 8.5e-10 39.3 0.1 4.6e-07 30.4 0.0 2.6 2 1 2 4 4 4 3 SET domain ATP-grasp_3 PF02655.14 GBG86680.1 - 0.00038 20.6 0.0 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 GBG86680.1 - 0.0059 16.2 0.0 0.05 13.2 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain SAF PF08666.12 GBG86680.1 - 0.0066 17.0 0.0 5.6 7.7 0.0 2.5 2 0 0 2 2 2 2 SAF domain ATPgrasp_Ter PF15632.6 GBG86680.1 - 0.0082 15.9 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 GBG86680.1 - 0.022 14.3 2.9 0.024 14.2 0.0 2.4 2 1 0 2 2 2 0 ATP-grasp domain SUIM_assoc PF16619.5 GBG86680.1 - 0.033 14.2 5.2 0.062 13.4 5.2 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RVT_1 PF00078.27 GBG86682.1 - 3.7e-25 88.7 0.0 7.1e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86682.1 - 1.6e-11 44.1 0.0 5.3e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86682.1 - 3.1e-06 27.7 0.0 1.2e-05 25.9 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86682.1 - 3.6e-06 27.4 0.0 1.8e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG86682.1 - 3.5e-05 24.0 9.5 0.00096 19.4 0.1 4.3 4 0 0 4 4 4 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG86682.1 - 0.00025 20.8 0.0 0.00069 19.4 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86682.1 - 0.0021 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG86682.1 - 0.008 16.5 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CLZ PF16526.5 GBG86682.1 - 0.16 12.3 5.7 0.23 11.8 0.6 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 GBG86682.1 - 1.5 8.1 14.6 0.18 11.1 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) LBR_tudor PF09465.10 GBG86683.1 - 5.2e-07 29.4 2.9 4.9e-05 23.0 0.3 2.5 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain RVT_1 PF00078.27 GBG86684.1 - 3.6e-35 121.5 0.1 5e-35 121.0 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAGAT PF03982.13 GBG86685.1 - 9.9e-32 110.0 0.1 1.4e-31 109.6 0.1 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 GBG86685.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase RT_RNaseH_2 PF17919.1 GBG86687.1 - 1.1e-29 102.4 0.0 6.4e-14 51.8 0.0 2.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86687.1 - 2.1e-28 98.7 0.0 5.2e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86687.1 - 2.4e-15 56.4 0.0 9.2e-15 54.5 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86687.1 - 1.6e-05 25.0 0.2 4.5e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG86687.1 - 5.7e-05 23.2 0.0 0.00048 20.3 0.0 2.4 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 GBG86687.1 - 6.1e-05 22.6 0.1 0.0013 18.3 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_5 PF14787.6 GBG86688.1 - 0.077 12.7 2.5 0.18 11.6 2.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RVT_1 PF00078.27 GBG86690.1 - 0.028 13.9 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Fungal_KA1 PF16797.5 GBG86690.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 GBG86692.1 - 4.3e-24 85.2 0.0 8.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86692.1 - 1.6e-22 80.2 0.0 5.7e-22 78.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 GBG86692.1 - 0.0013 19.5 3.3 4.7 8.2 0.0 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Shugoshin_N PF07558.11 GBG86692.1 - 0.0022 17.8 14.2 0.17 11.8 1.0 4.0 4 0 0 4 4 4 2 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 GBG86692.1 - 0.17 12.0 21.8 2.2 8.4 1.0 4.8 3 1 1 4 4 4 0 bZIP transcription factor M PF02370.16 GBG86692.1 - 0.35 11.6 15.6 6.1 7.8 0.1 4.7 4 0 0 4 4 3 0 M protein repeat Cep57_MT_bd PF06657.13 GBG86692.1 - 0.9 10.0 13.5 5.7 7.5 2.1 3.9 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 GBG86692.1 - 1.9 8.3 18.6 0.24 11.2 0.7 4.5 3 1 1 4 4 4 0 Septum formation initiator FlxA PF14282.6 GBG86692.1 - 3.7 7.6 8.8 1.8 8.6 3.2 3.0 1 1 1 2 2 2 0 FlxA-like protein BRE1 PF08647.11 GBG86692.1 - 3.9 7.6 13.0 1.2 9.3 2.9 3.5 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 GBG86692.1 - 3.9 6.7 17.4 1 8.6 3.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) GAS PF13851.6 GBG86692.1 - 4.9 6.5 26.9 0.6 9.4 9.7 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding SKA2 PF16740.5 GBG86692.1 - 4.9 7.0 13.0 17 5.2 4.1 3.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Snapin_Pallidin PF14712.6 GBG86692.1 - 6.3 7.3 13.7 1.9 9.0 1.5 2.8 2 0 0 2 2 2 0 Snapin/Pallidin DUF1664 PF07889.12 GBG86692.1 - 7.5 6.6 7.7 22 5.1 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 GBG86692.1 - 7.8 6.9 14.9 12 6.4 4.4 3.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Atg14 PF10186.9 GBG86692.1 - 8.3 5.4 21.8 6 5.8 9.3 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 GBG86692.1 - 8.9 4.7 13.7 13 4.1 13.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 GBG86692.1 - 9.1 6.4 29.3 0.21 11.6 14.5 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein zf-CCHC PF00098.23 GBG86693.1 - 4.5e-08 32.8 0.4 8e-08 32.0 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86693.1 - 0.012 15.4 0.8 0.019 14.8 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG86693.1 - 0.05 13.3 0.6 0.12 12.1 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle bHLH-MYC_N PF14215.6 GBG86693.1 - 0.097 13.0 4.6 0.14 12.4 4.6 1.2 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Nop53 PF07767.11 GBG86693.1 - 0.72 9.2 20.5 0.92 8.8 20.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Presenilin PF01080.17 GBG86693.1 - 2.3 6.9 5.7 2.4 6.8 5.7 1.1 1 0 0 1 1 1 0 Presenilin ATP_synt_H PF05493.13 GBG86694.1 - 3.9e-20 72.1 3.9 4.3e-20 71.9 3.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF3180 PF11377.8 GBG86694.1 - 0.026 14.7 0.8 0.03 14.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) ARL6IP6 PF15062.6 GBG86694.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix His_Phos_2 PF00328.22 GBG86695.1 - 6.1e-22 78.5 0.0 1.3e-12 47.8 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) EF-hand_7 PF13499.6 GBG86696.1 - 4e-26 91.3 1.1 5.8e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG86696.1 - 5.2e-25 85.1 7.6 2.4e-08 33.0 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GBG86696.1 - 1.6e-21 75.9 3.7 1.6e-14 53.5 0.2 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GBG86696.1 - 3.9e-21 73.1 1.8 1.5e-07 30.8 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GBG86696.1 - 6.5e-14 50.7 8.8 1.7e-06 27.3 0.2 3.8 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 GBG86696.1 - 5.8e-11 42.5 0.0 1.1e-05 25.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GBG86696.1 - 2.9e-05 24.4 0.2 0.056 13.8 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GBG86696.1 - 0.00031 20.6 0.3 0.025 14.6 0.0 2.3 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 GBG86696.1 - 0.0014 18.5 0.2 0.0014 18.5 0.2 2.4 3 1 1 4 4 4 1 EF hand Dockerin_1 PF00404.18 GBG86696.1 - 0.003 17.7 0.0 0.1 12.8 0.0 2.2 2 0 0 2 2 2 1 Dockerin type I domain DUF1722 PF08349.11 GBG86696.1 - 0.045 14.0 0.0 0.23 11.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) DNA_ligase_aden PF01653.18 GBG86696.1 - 0.061 12.4 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain DUF1456 PF07308.13 GBG86696.1 - 0.074 13.4 0.9 13 6.2 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Caleosin PF05042.13 GBG86696.1 - 0.08 12.9 0.2 0.6 10.0 0.2 2.5 1 1 0 1 1 1 0 Caleosin related protein RT_RNaseH_2 PF17919.1 GBG86697.1 - 1.2e-33 115.2 0.0 2.9e-33 113.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86697.1 - 2.3e-31 109.0 0.1 4.3e-31 108.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86697.1 - 1.1e-29 102.8 0.1 4.4e-29 100.8 0.1 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG86697.1 - 0.027 14.7 0.7 0.18 12.1 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG86697.1 - 0.044 13.8 0.7 0.092 12.7 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DASH_Duo1 PF08651.10 GBG86697.1 - 0.18 11.6 0.6 11 5.9 1.4 2.7 2 0 0 2 2 2 0 DASH complex subunit Duo1 Aegerolysin PF06355.13 GBG86698.1 - 1e-29 103.2 0.0 1.2e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Aegerolysin RVT_1 PF00078.27 GBG86700.1 - 0.00062 19.3 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_S3_C PF00189.20 GBG86700.1 - 0.026 15.0 0.8 0.62 10.6 0.1 3.1 3 0 0 3 3 3 0 Ribosomal protein S3, C-terminal domain RT_RNaseH_2 PF17919.1 GBG86701.1 - 5.2e-33 113.1 0.0 1.2e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86701.1 - 1e-30 106.1 0.1 2.3e-30 104.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86701.1 - 1.6e-14 53.8 0.1 3e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86701.1 - 1.8e-13 50.7 0.0 6.7e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG86701.1 - 0.019 15.2 0.1 0.067 13.4 0.1 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG86701.1 - 0.034 14.1 0.0 0.086 12.8 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain IL34 PF15036.6 GBG86701.1 - 0.054 13.5 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Interleukin 34 DUF1564 PF07600.11 GBG86701.1 - 0.067 12.9 0.1 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Dynactin_p22 PF07426.11 GBG86701.1 - 0.6 9.9 2.6 0.43 10.4 0.2 2.0 2 0 0 2 2 2 0 Dynactin subunit p22 tRNA-synt_1_2 PF13603.6 GBG86702.1 - 0.006 16.1 0.2 0.0087 15.6 0.2 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 TP53IP5 PF15331.6 GBG86702.1 - 2.8 8.0 11.8 3.1 7.9 11.8 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PA26 PF04636.13 GBG86702.1 - 4 6.2 10.0 5 5.9 10.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RVT_1 PF00078.27 GBG86703.1 - 2.6e-27 95.8 0.0 4.5e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86703.1 - 1.5e-26 92.3 0.0 4.2e-26 90.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86703.1 - 3.3e-14 53.0 0.0 6.7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG86703.1 - 9.1e-07 29.4 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86703.1 - 4.6e-06 27.2 0.0 9.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG86703.1 - 0.0033 17.2 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86703.1 - 0.014 15.2 0.5 0.035 13.9 0.1 1.9 2 0 0 2 2 2 0 Aspartyl protease DUF1758 PF05585.12 GBG86703.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) CoA_transf_3 PF02515.17 GBG86704.1 - 0.38 9.8 2.8 1.4 7.9 0.1 2.2 2 0 0 2 2 2 0 CoA-transferase family III rve PF00665.26 GBG86705.1 - 4.8e-14 52.6 0.0 1.1e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG86706.1 - 1e-48 163.9 1.4 1.6e-27 95.8 0.2 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86706.1 - 4e-46 155.1 0.2 2.1e-31 107.9 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86706.1 - 2.1e-42 145.1 0.2 1.1e-32 113.4 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86706.1 - 6.2e-14 52.2 0.2 9.7e-13 48.4 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain DUF1564 PF07600.11 GBG86706.1 - 0.0092 15.7 0.0 0.046 13.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) TOBE_2 PF08402.10 GBG86706.1 - 0.02 15.0 0.4 11 6.3 0.0 3.5 3 0 0 3 3 3 0 TOBE domain Pkinase PF00069.25 GBG86707.1 - 4e-37 128.0 0.0 6.6e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG86707.1 - 3.5e-19 69.1 0.0 5.3e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SelP_N PF04592.14 GBG86707.1 - 5.8 6.3 22.1 9.7 5.5 22.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PHP PF02811.19 GBG86708.1 - 0.088 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 PHP domain Retrotrans_gag PF03732.17 GBG86709.1 - 3e-05 24.2 3.6 0.0059 16.8 0.0 3.6 3 0 0 3 3 3 2 Retrotransposon gag protein ZapB PF06005.12 GBG86709.1 - 1.5 9.3 9.5 2.9 8.4 0.0 3.0 2 0 0 2 2 2 0 Cell division protein ZapB AIF-MLS PF14962.6 GBG86709.1 - 1.8 8.5 6.1 0.8 9.7 2.8 1.9 2 0 0 2 2 2 0 Mitochondria Localisation Sequence DUF4407 PF14362.6 GBG86709.1 - 3.9 6.7 11.8 34 3.7 9.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CLZ PF16526.5 GBG86709.1 - 5 7.6 9.6 0.89 10.0 0.6 3.0 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SDA1 PF05285.12 GBG86711.1 - 0.47 9.8 22.8 0.55 9.6 22.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG86711.1 - 0.56 8.3 20.9 0.66 8.1 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG86711.1 - 1.7 8.1 10.5 2.3 7.7 10.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 GBG86711.1 - 2.5 6.3 14.5 2.9 6.1 14.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TMEM213 PF15192.6 GBG86712.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 TMEM213 family Neur_chan_memb PF02932.16 GBG86712.1 - 0.23 11.5 3.9 0.4 10.7 3.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3439 PF11921.8 GBG86713.1 - 0.0012 18.8 11.8 0.0022 17.9 11.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) BUD22 PF09073.10 GBG86714.1 - 0.09 12.1 21.5 0.13 11.6 21.5 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG86714.1 - 0.34 10.3 28.4 0.45 9.9 28.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG86714.1 - 0.62 8.2 24.2 0.82 7.8 24.2 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 GBG86714.1 - 0.7 10.2 10.8 1.1 9.5 10.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3381 PF11861.8 GBG86714.1 - 0.83 9.4 16.8 1.5 8.6 16.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Hid1 PF12722.7 GBG86714.1 - 2.2 6.3 11.4 2.8 6.0 11.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SpoIIIAH PF12685.7 GBG86714.1 - 4.3 7.1 14.6 6.4 6.5 14.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.15 GBG86714.1 - 5.2 5.7 9.3 6.5 5.4 9.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop53 PF07767.11 GBG86714.1 - 6.1 6.1 25.0 8 5.7 25.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF913 PF06025.12 GBG86714.1 - 7.1 5.5 6.9 12 4.7 6.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 GBG86714.1 - 7.9 4.6 24.8 13 3.9 24.8 1.3 1 0 0 1 1 1 0 CDC45-like protein RICH PF05062.12 GBG86715.1 - 0.23 11.8 1.0 0.47 10.8 0.1 1.8 2 0 0 2 2 2 0 RICH domain Retrotrans_gag PF03732.17 GBG86716.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein Malic_M PF03949.15 GBG86717.1 - 1.8e-23 83.1 0.0 2.2e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Malic_M PF03949.15 GBG86718.1 - 2.6e-52 177.7 0.1 4.1e-52 177.0 0.1 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GBG86718.1 - 1.8e-49 168.0 0.6 1.3e-38 132.6 0.0 2.2 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain HetR_C PF18460.1 GBG86718.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain Myb_DNA-bind_4 PF13837.6 GBG86719.1 - 3.1e-08 33.9 2.0 3.1e-08 33.9 2.0 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG86719.1 - 0.00014 22.1 2.0 0.0019 18.4 0.3 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG86719.1 - 0.0035 17.5 0.3 0.008 16.3 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG86719.1 - 0.014 15.4 0.5 0.031 14.4 0.5 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG86721.1 - 1.5e-17 63.8 0.0 4.5e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86721.1 - 7.9e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein SpoIIP PF07454.11 GBG86722.1 - 0.0092 15.5 10.1 0.0092 15.5 10.1 1.4 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) Methyltransf_29 PF03141.16 GBG86724.1 - 5e-201 668.7 0.0 5.8e-201 668.5 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 GBG86724.1 - 2.3e-12 47.4 0.0 5.9e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GBG86724.1 - 3.2e-09 37.4 0.0 4.7e-05 24.0 0.0 3.1 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GBG86724.1 - 4.3e-07 29.9 0.0 0.0057 16.5 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GBG86724.1 - 4.4e-05 23.4 0.0 0.34 10.7 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GBG86724.1 - 0.0025 18.5 0.0 2 9.2 0.0 3.1 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 GBG86724.1 - 0.18 11.4 0.0 9.9 5.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Histone PF00125.24 GBG86725.1 - 4.5e-22 78.8 2.8 1.9e-21 76.8 0.0 2.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 AMP-binding PF00501.28 GBG86726.1 - 1.3e-23 83.3 0.0 3e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme GGACT PF06094.12 GBG86726.1 - 4.3e-13 49.9 0.1 6.7e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like N6_N4_Mtase PF01555.18 GBG86727.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 DNA methylase GARP PF16731.5 GBG86727.1 - 0.014 15.0 0.2 0.014 15.0 0.2 2.1 2 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma SDA1 PF05285.12 GBG86728.1 - 0.046 13.1 13.6 0.057 12.8 13.6 1.1 1 0 0 1 1 1 0 SDA1 RPA43_OB PF17875.1 GBG86728.1 - 0.23 12.1 6.2 0.53 10.9 6.1 1.6 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I HSP90 PF00183.18 GBG86728.1 - 0.47 9.3 5.1 0.59 9.0 5.1 1.1 1 0 0 1 1 1 0 Hsp90 protein Na_trans_assoc PF06512.13 GBG86728.1 - 0.99 9.7 10.9 1.3 9.2 10.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated SURF2 PF05477.11 GBG86728.1 - 2.1 8.0 6.4 2.1 8.0 4.2 2.0 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Mpp10 PF04006.12 GBG86728.1 - 2.1 6.7 14.9 2.6 6.4 14.9 1.0 1 0 0 1 1 1 0 Mpp10 protein zf-CCHC PF00098.23 GBG86730.1 - 8.9e-07 28.7 1.9 1.6e-06 27.9 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle LPP PF04728.13 GBG86730.1 - 0.059 13.8 9.8 2 8.9 0.1 5.0 4 1 0 4 4 4 0 Lipoprotein leucine-zipper CDC45 PF02724.14 GBG86731.1 - 1.6 6.9 7.7 2.1 6.5 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Metallophos PF00149.28 GBG86732.1 - 7.8e-41 140.8 0.1 9.8e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GBG86732.1 - 1.6e-21 76.4 1.1 1.6e-21 76.4 1.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain EF-hand_1 PF00036.32 GBG86733.1 - 1.7e-21 74.1 6.0 5.8e-09 34.9 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GBG86733.1 - 5.4e-20 69.5 2.5 4.5e-08 32.4 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 GBG86733.1 - 1.1e-18 67.5 2.6 3.3e-11 43.5 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GBG86733.1 - 4.3e-14 52.1 8.8 2.4e-07 30.5 0.2 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 GBG86733.1 - 6.8e-13 48.7 0.1 2.7e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GBG86733.1 - 7e-11 41.1 2.4 1.9e-06 27.1 0.1 3.0 3 0 0 3 3 3 2 EF hand Caleosin PF05042.13 GBG86733.1 - 6e-06 26.3 0.1 0.013 15.4 0.0 2.6 1 1 2 3 3 3 2 Caleosin related protein TerB PF05099.13 GBG86733.1 - 5.5e-05 23.2 0.2 0.02 14.8 0.1 2.1 2 0 0 2 2 2 2 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 GBG86733.1 - 0.00012 22.3 0.1 0.4 11.0 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.6 GBG86733.1 - 0.0014 19.0 0.3 0.56 10.7 0.1 2.2 1 1 1 2 2 2 2 Toprim-like Spore_III_AB PF09548.10 GBG86733.1 - 0.075 13.1 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) UPF0154 PF03672.13 GBG86733.1 - 0.1 12.6 0.0 5.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 GBG86733.1 - 0.11 12.8 0.1 9.3 6.7 0.0 2.5 1 1 0 2 2 2 0 EF-hand domain RNA_pol_Rpb4 PF03874.16 GBG86733.1 - 0.12 12.7 0.2 0.35 11.2 0.0 1.7 2 1 0 2 2 2 0 RNA polymerase Rpb4 RloB PF13707.6 GBG86733.1 - 0.19 11.9 2.3 5.8 7.1 0.3 2.1 1 1 1 2 2 2 0 RloB-like protein Glutaredoxin PF00462.24 GBG86735.1 - 2.7e-19 69.1 0.1 4.5e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 GBG86735.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 GBG86735.1 - 0.0024 18.3 0.0 0.0038 17.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RT_RNaseH_2 PF17919.1 GBG86736.1 - 6.8e-22 77.4 0.0 1.1e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86736.1 - 1.4e-21 76.8 0.0 2.4e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86736.1 - 3.8e-18 65.8 0.0 4.7e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PaaX_C PF08223.11 GBG86736.1 - 0.091 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain DUF668 PF05003.12 GBG86737.1 - 7e-26 90.5 2.0 7.2e-26 90.5 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF668) DUF3475 PF11961.8 GBG86737.1 - 2.2e-16 59.6 0.7 2.2e-16 59.6 0.7 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3475) SDA1 PF05285.12 GBG86737.1 - 0.033 13.6 7.6 0.078 12.4 7.6 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG86737.1 - 0.69 8.1 6.0 1.3 7.2 6.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_9 PF00759.19 GBG86738.1 - 4.3e-139 464.5 0.1 5.1e-139 464.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM49 PF09478.10 GBG86738.1 - 2.4e-08 34.1 0.0 4.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Peptidase_C78 PF07910.13 GBG86739.1 - 1.3e-50 171.9 0.1 1.9e-50 171.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 GBG86739.1 - 0.071 12.5 0.1 0.23 10.8 0.1 1.8 2 0 0 2 2 2 0 Peptidase family C54 Ribosomal_L1 PF00687.21 GBG86740.1 - 1.4e-45 155.6 0.0 2.2e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L1 PF00687.21 GBG86741.1 - 2.4e-44 151.5 0.0 4.5e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family EF-hand_1 PF00036.32 GBG86742.1 - 6.2e-31 103.6 11.1 1.5e-08 33.6 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GBG86742.1 - 5.4e-30 103.7 3.4 6.9e-15 55.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG86742.1 - 3.6e-23 79.5 8.6 9.1e-09 34.6 0.3 4.5 4 1 1 5 5 4 4 EF-hand domain EF-hand_8 PF13833.6 GBG86742.1 - 8.8e-19 67.1 11.3 3.2e-08 33.3 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GBG86742.1 - 1.2e-17 62.5 13.8 2.7e-07 29.8 0.1 4.9 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 GBG86742.1 - 3.2e-11 43.4 0.0 6.2e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 GBG86742.1 - 9.5e-06 25.9 0.4 0.18 12.2 0.4 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GBG86742.1 - 0.00018 21.4 2.1 0.16 11.9 0.6 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 GBG86742.1 - 0.0013 18.7 0.5 2.9 7.8 0.0 3.0 2 2 2 4 4 4 2 Caleosin related protein Toprim_2 PF13155.6 GBG86742.1 - 0.0015 18.9 0.5 0.63 10.5 0.1 2.4 1 1 1 2 2 2 1 Toprim-like EF-hand_14 PF17959.1 GBG86742.1 - 0.007 16.7 1.0 0.07 13.5 0.5 2.6 1 1 1 2 2 2 1 EF-hand domain DUF3349 PF11829.8 GBG86742.1 - 0.0084 16.9 0.1 0.45 11.3 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3349) Toprim_4 PF13662.6 GBG86742.1 - 0.011 16.2 0.2 5.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Toprim domain Toprim PF01751.22 GBG86742.1 - 0.016 15.4 0.2 1.2 9.4 0.0 2.3 1 1 1 2 2 2 0 Toprim domain ADSL_C PF10397.9 GBG86742.1 - 0.017 15.7 0.3 0.12 13.0 0.0 2.2 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus Cas_Csa5 PF09702.10 GBG86742.1 - 0.031 14.5 0.1 0.8 10.0 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) DUF1707 PF08044.11 GBG86742.1 - 0.037 14.1 0.1 0.63 10.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1707) NES_C_h PF18208.1 GBG86742.1 - 0.043 14.1 0.9 0.058 13.7 0.4 1.6 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain EF-hand_11 PF08976.11 GBG86742.1 - 0.072 14.0 0.0 8.3 7.3 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain Tachystatin_B PF11478.8 GBG86744.1 - 0.055 13.4 0.5 0.4 10.7 0.0 2.2 2 1 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B Arf PF00025.21 GBG86745.1 - 1.2e-44 151.9 0.0 1.4e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GBG86745.1 - 4.4e-18 65.4 0.0 5.1e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG86745.1 - 3.5e-16 59.5 0.0 5.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GBG86745.1 - 1.9e-10 40.5 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GBG86745.1 - 6.2e-08 32.7 0.0 3e-07 30.5 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 GBG86745.1 - 1.5e-07 31.0 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GBG86745.1 - 8.4e-07 28.5 0.0 1.7e-05 24.1 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 GBG86745.1 - 0.00096 18.7 0.0 0.013 15.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 GBG86745.1 - 0.048 13.7 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 GBG86745.1 - 0.081 12.5 0.1 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 GBG86745.1 - 0.11 12.1 0.0 0.87 9.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 GBG86745.1 - 0.12 12.4 0.0 3.7 7.6 0.1 2.2 1 1 1 2 2 2 0 Dynamin family AAA_7 PF12775.7 GBG86745.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Arf PF00025.21 GBG86746.1 - 2.3e-44 150.9 0.0 2.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GBG86746.1 - 4.5e-18 65.4 0.0 5.2e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG86746.1 - 3.6e-16 59.5 0.0 5.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GBG86746.1 - 2e-10 40.4 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GBG86746.1 - 6.3e-08 32.7 0.0 3.1e-07 30.5 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 GBG86746.1 - 1.5e-07 31.0 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GBG86746.1 - 8.2e-07 28.5 0.0 1.8e-05 24.1 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 GBG86746.1 - 0.00098 18.7 0.0 0.013 15.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 GBG86746.1 - 0.048 13.7 0.1 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 GBG86746.1 - 0.082 12.4 0.1 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 GBG86746.1 - 0.11 12.1 0.0 0.88 9.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 GBG86746.1 - 0.12 12.4 0.0 3.7 7.6 0.1 2.2 1 1 1 2 2 2 0 Dynamin family Retrotrans_gag PF03732.17 GBG86747.1 - 0.0036 17.5 0.1 0.013 15.7 0.1 1.9 1 1 1 2 2 2 1 Retrotransposon gag protein CheD PF03975.13 GBG86747.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 CheD chemotactic sensory transduction BUD22 PF09073.10 GBG86748.1 - 0.34 10.2 17.8 0.46 9.8 17.8 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG86748.1 - 0.48 9.8 15.9 0.64 9.4 15.9 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG86748.1 - 0.82 7.9 12.8 1.1 7.5 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG86748.1 - 1.8 6.7 17.9 2.4 6.3 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 GBG86748.1 - 2.4 7.2 10.4 3.3 6.7 10.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NDK PF00334.19 GBG86749.1 - 2.2e-49 166.9 0.0 4.9e-49 165.8 0.0 1.5 1 0 0 1 1 1 1 Nucleoside diphosphate kinase RVT_1 PF00078.27 GBG86749.1 - 1e-12 48.1 0.0 2.4e-12 46.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MatE PF01554.18 GBG86750.1 - 1.2e-38 132.3 28.2 4.1e-24 85.1 3.3 2.7 2 1 1 3 3 3 2 MatE VirB3 PF05101.13 GBG86750.1 - 2.6 8.3 11.5 0.13 12.5 4.1 2.6 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Chromo PF00385.24 GBG86751.1 - 2.6e-12 46.5 0.0 4.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG86751.1 - 6.9e-12 45.6 0.0 1.6e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG86752.1 - 3.4e-16 59.1 0.0 7e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86752.1 - 7.1e-08 32.2 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86752.1 - 3.1e-06 27.4 0.0 6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RPN2_C PF18004.1 GBG86752.1 - 2.5 8.0 10.2 4.5 7.2 10.2 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Vfa1 PF08432.10 GBG86752.1 - 3.6 7.9 9.6 5.5 7.3 9.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pyr_redox_2 PF07992.14 GBG86753.1 - 3.5e-46 157.8 0.2 4.3e-46 157.5 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GBG86753.1 - 1.2e-11 45.1 3.1 2e-11 44.3 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG86753.1 - 0.03 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GBG86753.1 - 1.8 8.1 5.7 7.1 6.1 0.0 3.5 4 1 0 4 4 4 0 FAD dependent oxidoreductase Baculo_PEP_C PF04513.12 GBG86756.1 - 2.1 8.4 11.4 6.4 6.8 4.0 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 GBG86756.1 - 3.7 8.1 4.4 3.7 8.1 1.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC_tran PF00005.27 GBG86757.1 - 2.1e-47 161.1 5.3 3.6e-23 82.6 0.0 3.2 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 GBG86757.1 - 3.5e-19 69.7 3.1 0.00024 21.0 0.1 4.7 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 GBG86757.1 - 6.8e-08 32.9 1.2 0.0035 17.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 GBG86757.1 - 9.3e-08 32.2 0.3 0.0005 20.0 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 GBG86757.1 - 4.3e-07 29.6 7.2 0.28 10.6 0.0 4.5 3 2 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GBG86757.1 - 3.3e-06 27.7 8.7 0.0043 17.6 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 GBG86757.1 - 5.4e-06 26.1 0.7 0.0088 15.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG86757.1 - 5.7e-06 26.8 0.6 0.049 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 GBG86757.1 - 8.4e-06 25.8 0.2 0.0031 17.6 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GBG86757.1 - 5.1e-05 23.6 0.1 0.44 10.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 GBG86757.1 - 5.9e-05 23.5 0.1 0.82 10.1 0.0 3.5 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GBG86757.1 - 0.00012 22.6 0.1 0.98 10.0 0.1 3.3 2 1 0 2 2 2 2 AAA domain cobW PF02492.19 GBG86757.1 - 0.00014 21.5 0.1 0.37 10.4 0.0 2.9 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 GBG86757.1 - 0.00016 21.5 5.2 0.65 9.6 0.1 4.5 5 0 0 5 5 5 1 AAA ATPase domain NACHT PF05729.12 GBG86757.1 - 0.00023 21.1 0.1 0.45 10.4 0.0 2.4 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 GBG86757.1 - 0.00026 21.3 0.0 0.14 12.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ABC_tran_Xtn PF12848.7 GBG86757.1 - 0.00029 20.8 7.1 0.00029 20.8 7.1 3.3 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.6 GBG86757.1 - 0.00054 19.7 0.5 0.67 9.6 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 GBG86757.1 - 0.0012 19.1 0.4 1.5 9.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 GBG86757.1 - 0.0024 18.0 4.6 0.16 12.0 0.0 4.1 3 1 1 4 4 4 1 Dynamin family AAA_5 PF07728.14 GBG86757.1 - 0.0034 17.4 0.1 1.5 8.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GBG86757.1 - 0.0044 17.1 0.4 5.6 7.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 GBG86757.1 - 0.008 16.1 0.0 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 GBG86757.1 - 0.01 15.5 0.0 0.26 10.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 GBG86757.1 - 0.016 14.9 2.7 2 8.1 0.0 3.4 4 1 0 4 4 3 0 AAA domain SRP54 PF00448.22 GBG86757.1 - 0.02 14.5 0.0 7.9 6.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 GBG86757.1 - 0.034 13.3 0.0 8.2 5.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 GBG86757.1 - 0.045 13.3 0.1 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GBG86757.1 - 0.047 13.6 0.0 6.3 6.7 0.0 2.7 2 0 0 2 2 2 0 NTPase Roc PF08477.13 GBG86757.1 - 0.053 13.7 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 GBG86757.1 - 0.061 12.9 2.4 2.2 7.8 0.1 3.3 3 0 0 3 3 3 0 AAA domain dNK PF01712.19 GBG86757.1 - 0.093 12.6 0.0 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase Peptidase_M13 PF01431.21 GBG86757.1 - 0.18 11.4 0.3 0.3 10.7 0.3 1.2 1 0 0 1 1 1 0 Peptidase family M13 DUF87 PF01935.17 GBG86757.1 - 0.25 11.4 1.6 4.8 7.2 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain Thymidylate_kin PF02223.17 GBG86757.1 - 1.2 8.7 4.1 13 5.4 0.0 3.4 4 0 0 4 4 4 0 Thymidylate kinase AAA_17 PF13207.6 GBG86757.1 - 5 7.5 8.6 30 5.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA_13 PF13166.6 GBG86757.1 - 6.5 5.3 11.7 3.9 6.0 0.0 3.8 4 0 0 4 4 4 0 AAA domain RT_RNaseH PF17917.1 GBG86758.1 - 1.9e-22 79.6 0.0 4.2e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86758.1 - 2.9e-22 78.6 0.0 6.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86758.1 - 2.6e-06 27.1 0.0 5.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3089 PF11288.8 GBG86759.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF659 PF04937.15 GBG86761.1 - 1.7e-07 31.2 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Ldl_recept_a PF00057.18 GBG86762.1 - 6.5e-44 147.9 138.2 3e-09 36.9 4.6 11.0 12 0 0 12 12 12 10 Low-density lipoprotein receptor domain class A DDE_Tnp_4 PF13359.6 GBG86763.1 - 1e-26 93.5 0.0 5e-26 91.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86763.1 - 1.3e-10 41.2 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG86763.1 - 0.0013 18.4 0.0 0.1 12.2 0.0 2.9 3 0 0 3 3 3 1 Transposase DDE domain Ldl_recept_a PF00057.18 GBG86765.1 - 2.5e-40 136.4 140.2 2.4e-08 34.0 8.7 11.2 11 1 0 11 11 11 10 Low-density lipoprotein receptor domain class A DDE_Tnp_4 PF13359.6 GBG86767.1 - 9.2e-27 93.7 0.0 1.4e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86767.1 - 6.6e-11 42.2 0.0 9.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG86767.1 - 0.012 15.3 0.1 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG86767.1 - 0.11 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG86769.1 - 0.00019 21.8 0.2 0.003 17.9 0.0 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain WBP-1 PF11669.8 GBG86769.1 - 0.025 15.2 0.0 0.06 14.0 0.0 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 Ldl_recept_a PF00057.18 GBG86770.1 - 4e-44 148.5 138.8 1.4e-08 34.8 9.6 11.0 10 1 1 11 11 11 9 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 GBG86771.1 - 2.7e-38 129.9 148.9 1.1e-07 32.0 9.1 11.5 10 2 2 12 12 12 10 Low-density lipoprotein receptor domain class A DUF659 PF04937.15 GBG86772.1 - 2.6e-19 69.6 0.0 4.5e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG86774.1 - 4.3e-23 81.6 0.0 1e-22 80.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86774.1 - 9.8e-23 80.1 0.0 2.3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86774.1 - 6e-22 78.3 0.0 2.1e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86774.1 - 7.8e-18 64.3 0.2 2e-17 63.0 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86774.1 - 0.0029 17.8 0.0 0.0083 16.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger CDC27 PF09507.10 GBG86774.1 - 0.073 12.5 19.9 0.14 11.5 19.9 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.6 GBG86774.1 - 0.41 11.0 8.2 1.2 9.6 8.2 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 GBG86774.1 - 0.47 10.1 16.5 1.2 8.8 16.5 1.6 1 0 0 1 1 1 0 FAM176 family Retrotrans_gag PF03732.17 GBG86774.1 - 0.53 10.6 0.0 0.53 10.6 0.0 2.6 2 0 0 2 2 1 0 Retrotransposon gag protein NOA36 PF06524.12 GBG86774.1 - 0.64 9.3 20.4 0.22 10.8 17.3 1.8 2 0 0 2 2 2 0 NOA36 protein DNA_pol_phi PF04931.13 GBG86774.1 - 0.66 8.0 27.2 0.96 7.5 27.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 GBG86774.1 - 0.82 9.8 11.3 1.9 8.6 11.3 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.12 GBG86774.1 - 0.87 8.9 23.2 1.6 8.1 23.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GBG86774.1 - 0.9 7.8 17.7 1.4 7.2 17.7 1.3 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.19 GBG86774.1 - 1.1 7.1 17.4 1.7 6.4 17.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RPN2_C PF18004.1 GBG86774.1 - 1.5 8.7 19.0 3.1 7.7 19.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPP4R2 PF09184.11 GBG86774.1 - 1.6 8.2 28.9 2.8 7.5 28.9 1.3 1 0 0 1 1 1 0 PPP4R2 BSP_II PF05432.11 GBG86774.1 - 1.9 8.1 33.2 4.7 6.8 33.2 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) AAA_23 PF13476.6 GBG86774.1 - 2.7 8.4 21.1 5.6 7.4 21.1 1.4 1 0 0 1 1 1 0 AAA domain Pox_Ag35 PF03286.14 GBG86774.1 - 3.1 7.5 18.1 8.6 6.1 18.1 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.12 GBG86774.1 - 3.1 7.1 26.7 5.3 6.4 26.7 1.3 1 0 0 1 1 1 0 SDA1 HSP90 PF00183.18 GBG86774.1 - 3.4 6.5 22.0 5.4 5.8 22.0 1.2 1 0 0 1 1 1 0 Hsp90 protein TFB6 PF17110.5 GBG86774.1 - 4.8 6.9 11.7 9.9 5.9 11.7 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Tim54 PF11711.8 GBG86774.1 - 5.2 5.8 17.2 12 4.6 15.4 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.12 GBG86774.1 - 9 4.4 29.9 14 3.7 29.9 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GBG86774.1 - 9.9 5.9 26.1 18 5.0 26.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FPN1 PF06963.12 GBG86775.1 - 1.2e-26 93.3 0.3 1.3e-26 93.1 0.3 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF2929 PF11151.8 GBG86775.1 - 0.085 13.2 0.3 0.16 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2929) RT_RNaseH_2 PF17919.1 GBG86776.1 - 1.5e-32 111.5 0.1 3.2e-32 110.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86776.1 - 1.5e-29 102.3 0.2 3.2e-29 101.3 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86776.1 - 2.7e-21 76.1 0.1 2e-19 70.0 0.0 2.5 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86776.1 - 1.3e-19 70.1 0.1 2.6e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86776.1 - 1.2e-15 57.7 0.0 4.8e-15 55.8 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86776.1 - 6.8e-05 23.3 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG86776.1 - 0.00049 19.9 0.0 0.00091 19.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG86776.1 - 0.0042 16.9 0.1 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG86776.1 - 0.0082 16.3 0.0 0.029 14.6 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG86776.1 - 0.036 14.7 0.0 0.081 13.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease FPN1 PF06963.12 GBG86777.1 - 2.4e-91 306.5 6.3 4.9e-91 305.5 6.3 1.4 1 1 0 1 1 1 1 Ferroportin1 (FPN1) FPN1 PF06963.12 GBG86778.1 - 3.7e-57 193.8 3.3 7.9e-57 192.7 3.3 1.4 1 1 0 1 1 1 1 Ferroportin1 (FPN1) EF-hand_1 PF00036.32 GBG86778.1 - 1.2e-09 37.0 2.9 5.7e-06 25.5 0.7 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GBG86778.1 - 2.8e-09 36.2 4.7 3.6e-05 23.3 0.4 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 GBG86778.1 - 6.6e-09 36.1 3.9 0.00018 21.9 2.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG86778.1 - 4.5e-05 22.7 4.6 0.00063 19.1 0.3 3.0 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 GBG86778.1 - 0.001 19.0 1.2 0.0022 17.9 0.7 1.8 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 GBG86778.1 - 0.031 14.1 6.7 0.052 13.4 1.5 2.9 3 0 0 3 3 3 0 EF-hand domain pair FPN1 PF06963.12 GBG86779.1 - 3.4e-27 95.1 0.2 4.3e-27 94.8 0.2 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Prefoldin_2 PF01920.20 GBG86780.1 - 5.2e-24 84.2 0.0 6.5e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 GBG86780.1 - 0.00064 19.6 0.3 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 Prefoldin subunit TSC22 PF01166.18 GBG86780.1 - 0.0013 19.0 0.5 0.072 13.4 0.1 2.3 2 0 0 2 2 2 1 TSC-22/dip/bun family DivIVA PF05103.13 GBG86780.1 - 0.0024 17.9 1.2 0.18 11.9 0.2 2.1 2 0 0 2 2 2 1 DivIVA protein Med9 PF07544.13 GBG86780.1 - 0.016 15.3 0.6 0.062 13.4 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4201 PF13870.6 GBG86780.1 - 0.024 14.4 1.7 0.26 11.0 1.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 GBG86780.1 - 0.035 14.2 2.2 2.2 8.3 0.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MAD PF05557.13 GBG86780.1 - 0.048 12.0 1.8 0.09 11.1 1.7 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF1664 PF07889.12 GBG86780.1 - 0.099 12.7 0.2 3.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 GBG86780.1 - 0.26 11.5 2.4 15 5.9 0.2 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YL1 PF05764.13 GBG86781.1 - 0.013 15.6 22.5 0.02 15.1 22.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GBG86781.1 - 5.7 5.0 26.2 8.2 4.5 26.2 1.1 1 0 0 1 1 1 0 Nop14-like family PG_binding_1 PF01471.18 GBG86782.1 - 2.9e-32 110.6 0.2 2.8e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 GBG86782.1 - 1.7e-07 31.4 2.9 0.059 13.6 0.1 4.0 2 2 2 4 4 4 3 Predicted Peptidoglycan domain PG_binding_1 PF01471.18 GBG86783.1 - 2.1e-29 101.5 0.0 5e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 GBG86783.1 - 1.4e-08 34.9 0.5 0.00066 19.9 0.0 3.3 2 2 1 3 3 3 3 Predicted Peptidoglycan domain Integrase_H2C2 PF17921.1 GBG86784.1 - 1.6e-14 53.7 0.2 1.6e-14 53.7 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86784.1 - 5.8e-11 42.6 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG86784.1 - 0.00055 20.1 0.1 0.0013 19.0 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG86784.1 - 0.0041 16.9 0.6 0.012 15.4 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Peptidase_C48 PF02902.19 GBG86785.1 - 5.1e-21 75.5 0.0 9.1e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4746 PF15928.5 GBG86785.1 - 1.6 8.1 11.8 2.5 7.5 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 GBG86785.1 - 3.4 5.6 24.6 4.9 5.1 24.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF604 PF04646.12 GBG86787.1 - 1.2e-66 224.8 0.0 2e-66 224.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 GBG86787.1 - 2.1e-15 56.8 0.0 3.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 GBG86787.1 - 0.51 10.1 1.8 0.71 9.7 0.0 1.9 2 0 0 2 2 2 0 Galactosyltransferase Macoilin PF09726.9 GBG86789.1 - 0.0046 15.6 3.6 0.0062 15.2 3.6 1.2 1 0 0 1 1 1 1 Macoilin family Spc7 PF08317.11 GBG86789.1 - 0.0047 15.9 16.8 0.13 11.1 16.8 2.4 2 0 0 2 2 2 1 Spc7 kinetochore protein LURAP PF14854.6 GBG86789.1 - 0.047 13.6 0.5 0.14 12.1 0.5 1.8 1 0 0 1 1 1 0 Leucine rich adaptor protein Syntaxin_2 PF14523.6 GBG86789.1 - 2 8.8 6.0 5 7.5 0.2 2.7 2 0 0 2 2 2 0 Syntaxin-like protein AAA_13 PF13166.6 GBG86789.1 - 7.6 5.0 13.3 8.7 4.9 12.3 1.5 1 1 0 1 1 1 0 AAA domain IF-2B PF01008.17 GBG86792.1 - 6.4e-46 156.8 0.0 9.6e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family IF-2B PF01008.17 GBG86793.1 - 4e-53 180.4 0.0 6.9e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family GvpL_GvpF PF06386.11 GBG86793.1 - 0.012 15.5 1.5 0.024 14.6 1.5 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF RT_RNaseH_2 PF17919.1 GBG86794.1 - 6.4e-34 116.0 0.1 1.2e-33 115.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86794.1 - 1.4e-31 109.8 0.1 2.2e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86794.1 - 7.5e-30 103.3 0.1 1.4e-29 102.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86794.1 - 1.7e-20 72.8 0.1 3.6e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86794.1 - 2.3e-15 56.8 0.0 6.6e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG86794.1 - 0.019 15.2 0.0 0.087 13.1 0.0 2.2 1 0 0 1 1 1 0 H2C2 zinc finger DUF5095 PF17016.5 GBG86794.1 - 0.2 11.3 0.1 0.36 10.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) ASF1_hist_chap PF04729.13 GBG86795.1 - 2.6e-70 235.3 0.7 3.2e-70 235.0 0.7 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RVT_1 PF00078.27 GBG86796.1 - 2e-26 92.9 0.0 3.6e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CLAMP PF14769.6 GBG86796.1 - 2.2e-17 63.3 1.3 6.1e-17 61.9 1.3 1.8 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 DUF4187 PF13821.6 GBG86796.1 - 0.018 14.8 0.3 0.018 14.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Alpha_E2_glycop PF00943.19 GBG86796.1 - 0.035 12.8 0.2 0.055 12.2 0.2 1.2 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein RVT_1 PF00078.27 GBG86798.1 - 6.9e-24 84.6 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86798.1 - 2e-05 24.7 0.0 4.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG86798.1 - 0.028 15.1 0.0 0.16 12.7 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Kelch_4 PF13418.6 GBG86799.1 - 2.3e-53 178.0 14.8 7.1e-13 48.4 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GBG86799.1 - 9.3e-44 147.0 4.8 2.4e-09 37.3 0.0 6.0 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GBG86799.1 - 2.8e-43 144.8 4.4 9e-09 35.3 0.0 5.5 3 1 2 5 5 5 5 Kelch motif Kelch_1 PF01344.25 GBG86799.1 - 5.9e-43 144.2 2.5 1.7e-10 40.3 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GBG86799.1 - 6.1e-35 117.9 10.8 2.6e-07 30.3 0.0 6.7 7 0 0 7 7 7 5 Kelch motif Kelch_5 PF13854.6 GBG86799.1 - 2e-34 117.0 2.2 6.5e-07 29.2 0.0 6.8 7 0 0 7 7 7 5 Kelch motif TIG PF01833.24 GBG86800.1 - 2.6e-21 75.5 3.7 3.2e-14 52.8 2.6 2.3 2 0 0 2 2 2 2 IPT/TIG domain RT_RNaseH_2 PF17919.1 GBG86801.1 - 1.8e-30 104.9 0.0 4.8e-30 103.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86801.1 - 2.9e-30 104.7 0.0 7.7e-30 103.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86801.1 - 2.4e-07 30.5 0.3 9e-05 22.1 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) CSRNP_N PF16019.5 GBG86801.1 - 2.2 8.1 9.6 0.32 10.9 3.1 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Zip PF02535.22 GBG86802.1 - 6.7e-30 104.4 3.2 1e-29 103.8 3.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4149 PF13664.6 GBG86802.1 - 0.099 13.0 0.4 0.22 11.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF659 PF04937.15 GBG86804.1 - 1.2e-08 34.9 0.9 2.6e-08 33.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG86804.1 - 5.6e-06 26.1 0.1 1.3e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TIG PF01833.24 GBG86805.1 - 1.5e-08 34.6 0.7 2.7e-08 33.8 0.7 1.4 1 0 0 1 1 1 1 IPT/TIG domain DUF2284 PF10050.9 GBG86805.1 - 0.054 13.2 1.1 0.11 12.2 1.1 1.4 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) GLEYA PF10528.9 GBG86805.1 - 0.11 12.9 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 GLEYA domain rve PF00665.26 GBG86807.1 - 8.9e-15 54.9 0.0 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain TIG PF01833.24 GBG86808.1 - 2e-30 104.7 11.5 1.6e-08 34.5 0.1 5.0 4 1 0 4 4 4 4 IPT/TIG domain RVT_1 PF00078.27 GBG86808.1 - 5e-15 55.6 0.1 7.9e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG86809.1 - 1e-13 51.4 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86809.1 - 2.5e-09 37.1 0.0 4.7e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG86809.1 - 0.012 14.7 0.1 0.018 14.2 0.1 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH PF17917.1 GBG86809.1 - 0.029 14.7 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG86810.1 - 2.2e-08 33.9 0.0 6.6e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86810.1 - 1.2e-06 29.0 0.0 4.9e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86810.1 - 2.5e-06 27.9 0.0 2e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86810.1 - 3.5e-05 23.6 0.0 6.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG86810.1 - 0.0048 17.1 0.1 0.027 14.8 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG86810.1 - 0.055 13.6 1.2 0.11 12.6 1.2 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation MscS_porin PF12795.7 GBG86810.1 - 3.5 7.1 9.6 0.75 9.3 5.5 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TIG PF01833.24 GBG86811.1 - 3.8e-32 110.2 13.1 1.7e-10 40.8 0.5 4.4 4 0 0 4 4 4 4 IPT/TIG domain RVT_1 PF00078.27 GBG86811.1 - 8e-25 87.6 0.1 1.8e-24 86.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PA14 PF07691.12 GBG86811.1 - 9.7e-05 22.2 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 PA14 domain RVT_1 PF00078.27 GBG86812.1 - 3.3e-11 43.1 0.0 5.4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG86812.1 - 0.00086 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RT_RNaseH_2 PF17919.1 GBG86813.1 - 1.1e-58 195.4 0.0 4.9e-34 116.3 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86813.1 - 2.5e-48 162.7 0.0 8.1e-24 83.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86813.1 - 1.2e-36 126.3 3.6 5.3e-23 81.7 0.1 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86813.1 - 6.6e-17 61.4 0.3 1.3e-16 60.4 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86813.1 - 7.9e-17 61.6 0.1 5.5e-13 49.2 0.0 3.3 3 0 0 3 3 3 2 Integrase core domain RVP_2 PF08284.11 GBG86813.1 - 2.1e-08 34.0 0.0 4.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86813.1 - 7.3e-08 32.9 0.0 1.9e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86813.1 - 1.1e-05 25.9 0.0 4.1e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86813.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG86813.1 - 0.11 12.8 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger MLTR_LBD PF17765.1 GBG86813.1 - 0.79 9.8 8.7 0.16 12.1 1.6 3.2 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain G8 PF10162.9 GBG86814.1 - 3.5e-29 101.4 0.0 6.4e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 G8 domain RT_RNaseH_2 PF17919.1 GBG86814.1 - 1.3e-26 92.6 0.1 2.1e-26 91.9 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86814.1 - 9.8e-26 90.1 0.0 1.7e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86814.1 - 3e-19 68.9 0.2 4.9e-19 68.2 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86814.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain BSP PF04450.12 GBG86815.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase of plants and bacteria Pkinase_Tyr PF07714.17 GBG86816.1 - 4e-08 32.9 0.0 8.8e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86816.1 - 4.6e-06 26.2 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CENP-F_leu_zip PF10473.9 GBG86816.1 - 0.00013 22.0 36.9 0.015 15.3 6.5 2.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 GBG86816.1 - 0.0015 18.0 30.9 0.42 9.9 11.9 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 GBG86816.1 - 0.0018 17.7 12.2 0.003 17.0 12.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CtIP_N PF10482.9 GBG86816.1 - 0.002 18.2 10.4 0.002 18.2 10.4 3.0 1 1 2 3 3 3 1 Tumour-suppressor protein CtIP N-terminal domain Cep57_MT_bd PF06657.13 GBG86816.1 - 0.0026 18.2 22.9 0.055 13.9 6.1 4.4 1 1 3 4 4 4 2 Centrosome microtubule-binding domain of Cep57 TPR_MLP1_2 PF07926.12 GBG86816.1 - 0.0058 16.7 30.9 0.095 12.8 15.7 3.1 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 GBG86816.1 - 0.0068 16.7 15.5 0.9 9.9 3.5 3.3 3 0 0 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.8 GBG86816.1 - 0.014 13.0 26.5 0.029 11.9 26.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Lip_prot_lig_C PF10437.9 GBG86816.1 - 0.016 15.2 8.3 6.6 6.8 0.2 3.9 2 1 2 4 4 4 0 Bacterial lipoate protein ligase C-terminus ADIP PF11559.8 GBG86816.1 - 0.016 15.3 25.4 0.061 13.4 6.8 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 GBG86816.1 - 0.022 15.2 28.0 0.15 12.4 1.7 5.2 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) BBP1_C PF15272.6 GBG86816.1 - 0.044 13.6 24.0 0.85 9.4 7.6 2.9 1 1 2 3 3 3 0 Spindle pole body component BBP1, C-terminal DUF4140 PF13600.6 GBG86816.1 - 0.045 14.2 21.8 0.14 12.6 6.9 3.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 GBG86816.1 - 0.083 13.1 23.4 0.6 10.4 2.6 3.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Filament PF00038.21 GBG86816.1 - 0.12 12.0 31.0 0.39 10.3 31.0 2.0 1 1 0 1 1 1 0 Intermediate filament protein DUF3450 PF11932.8 GBG86816.1 - 0.15 11.3 21.6 0.17 11.1 1.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) AKNA PF12443.8 GBG86816.1 - 0.16 12.6 9.5 0.92 10.2 0.7 2.5 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF1465 PF07323.12 GBG86816.1 - 0.16 11.8 14.3 0.49 10.2 5.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) HlyD_2 PF12700.7 GBG86816.1 - 0.3 9.8 14.7 0.16 10.7 5.1 2.1 1 1 1 2 2 2 0 HlyD family secretion protein bZIP_Maf PF03131.17 GBG86816.1 - 0.36 11.4 22.2 0.12 12.9 5.5 3.4 1 1 2 3 3 3 0 bZIP Maf transcription factor Phage_GPO PF05929.11 GBG86816.1 - 0.41 10.2 16.9 0.48 10.0 5.1 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Baculo_PEP_C PF04513.12 GBG86816.1 - 0.47 10.5 2.6 4.6 7.3 0.2 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 GBG86816.1 - 0.47 9.9 31.7 0.61 9.5 19.5 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 GBG86816.1 - 0.56 9.0 30.9 0.87 8.4 9.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein LPP PF04728.13 GBG86816.1 - 0.57 10.6 5.5 4.4 7.8 0.3 3.6 4 0 0 4 4 3 0 Lipoprotein leucine-zipper HAUS-augmin3 PF14932.6 GBG86816.1 - 0.62 9.6 23.0 1.8 8.0 3.5 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FapA PF03961.13 GBG86816.1 - 0.74 8.4 22.1 1.4 7.5 7.2 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A ZapB PF06005.12 GBG86816.1 - 0.98 9.9 36.8 0.74 10.3 6.3 3.9 2 1 2 4 4 4 0 Cell division protein ZapB Prefoldin_2 PF01920.20 GBG86816.1 - 1 9.3 27.0 1.1 9.3 1.9 4.3 1 1 2 4 4 4 0 Prefoldin subunit FH2 PF02181.23 GBG86816.1 - 1.2 8.2 19.7 78 2.2 19.6 2.3 1 1 0 1 1 1 0 Formin Homology 2 Domain APG6_N PF17675.1 GBG86816.1 - 1.5 9.3 35.4 5.9 7.4 11.6 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region FAM184 PF15665.5 GBG86816.1 - 1.6 8.4 33.0 1e+02 2.6 33.1 2.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B HeLo PF14479.6 GBG86816.1 - 2 8.2 16.3 9.1 6.1 1.0 2.4 1 1 1 2 2 2 0 Prion-inhibition and propagation DUF743 PF05332.11 GBG86816.1 - 2.4 8.3 7.1 15 5.7 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF743) DUF5082 PF16888.5 GBG86816.1 - 2.4 8.4 12.9 6.1 7.1 4.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4200 PF13863.6 GBG86816.1 - 2.5 8.5 31.8 2.1 8.8 13.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) FUSC PF04632.12 GBG86816.1 - 2.9 6.3 10.9 4.5 5.7 10.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cluap1 PF10234.9 GBG86816.1 - 3.6 6.9 29.0 4.5 6.6 9.7 3.0 1 1 0 2 2 2 0 Clusterin-associated protein-1 Rnk_N PF14760.6 GBG86816.1 - 4.4 7.9 13.2 4.2 7.9 1.1 3.8 4 0 0 4 4 3 0 Rnk N-terminus Herpes_UL6 PF01763.16 GBG86816.1 - 5 5.5 16.6 3.8 5.9 4.7 2.8 1 1 2 3 3 3 0 Herpesvirus UL6 like CLZ PF16526.5 GBG86816.1 - 5.7 7.4 27.2 2 8.8 7.4 4.2 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SHE3 PF17078.5 GBG86816.1 - 5.8 6.6 19.9 32 4.1 5.4 2.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 ABC_tran_CTD PF16326.5 GBG86816.1 - 5.8 7.2 28.5 42 4.5 10.0 4.2 1 1 2 3 3 3 0 ABC transporter C-terminal domain DivIC PF04977.15 GBG86816.1 - 6.6 6.6 23.1 0.59 9.9 2.7 4.2 2 2 2 4 4 4 0 Septum formation initiator Fer4_24 PF18109.1 GBG86816.1 - 7.6 6.9 7.1 6.5 7.1 0.2 3.7 5 0 0 5 5 3 0 Ferredoxin I 4Fe-4S cluster domain XhlA PF10779.9 GBG86816.1 - 8.2 6.7 20.0 4 7.7 1.4 4.3 3 2 1 4 4 4 0 Haemolysin XhlA Myb_DNA-bind_4 PF13837.6 GBG86817.1 - 1.8e-05 25.0 1.6 1.8e-05 25.0 1.6 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RIG-I_C-RD PF11648.8 GBG86817.1 - 0.045 14.0 0.1 0.25 11.6 0.0 2.2 1 1 1 2 2 2 0 C-terminal domain of RIG-I ABC_tran PF00005.27 GBG86818.1 - 4.2e-24 85.6 0.0 8.2e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG86818.1 - 8.5e-17 61.3 14.8 8.5e-17 61.3 14.8 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG86818.1 - 1.5e-08 34.8 0.0 1.2e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GBG86818.1 - 0.025 14.0 0.2 0.7 9.3 0.0 2.3 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GBG86818.1 - 0.027 14.2 0.0 0.56 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF4162 PF13732.6 GBG86818.1 - 0.038 14.7 0.0 0.067 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) HTH_47 PF16221.5 GBG86818.1 - 0.15 11.6 0.1 0.44 10.1 0.1 1.8 1 0 0 1 1 1 0 winged helix-turn-helix Pkinase_Tyr PF07714.17 GBG86820.1 - 1.8e-23 83.2 0.0 2.8e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86820.1 - 7.7e-22 77.9 0.0 1.5e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG86820.1 - 3.9e-09 37.0 3.0 2e-05 25.2 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Lip_prot_lig_C PF10437.9 GBG86820.1 - 0.012 15.6 4.4 0.56 10.2 0.4 3.5 2 2 2 4 4 4 0 Bacterial lipoate protein ligase C-terminus Nup160 PF11715.8 GBG86820.1 - 0.16 10.6 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 FAM184 PF15665.5 GBG86820.1 - 1.1 9.0 40.4 1.2 8.9 10.9 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B TEX13 PF15186.6 GBG86820.1 - 1.1 8.9 22.0 0.44 10.2 5.1 2.4 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF3584 PF12128.8 GBG86820.1 - 2 5.8 26.1 3.7 5.0 26.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cep57_MT_bd PF06657.13 GBG86820.1 - 3.9 8.0 24.6 17 5.9 6.2 4.6 1 1 3 5 5 5 0 Centrosome microtubule-binding domain of Cep57 BBP1_C PF15272.6 GBG86820.1 - 7.3 6.4 24.0 5.5 6.8 9.2 2.4 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Pkinase PF00069.25 GBG86821.1 - 2.2e-13 50.2 0.0 5.9e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG86821.1 - 1.5e-12 47.4 0.0 3.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase OmpH PF03938.14 GBG86821.1 - 0.0055 17.1 22.5 0.19 12.0 6.0 2.3 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Filament PF00038.21 GBG86821.1 - 0.007 16.0 9.2 0.007 16.0 9.2 3.1 1 1 2 3 3 3 1 Intermediate filament protein Lip_prot_lig_C PF10437.9 GBG86821.1 - 0.0075 16.2 5.4 29 4.7 0.1 4.6 2 2 3 5 5 5 0 Bacterial lipoate protein ligase C-terminus CENP-F_leu_zip PF10473.9 GBG86821.1 - 0.045 13.8 39.7 2.8 8.0 7.5 4.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM184 PF15665.5 GBG86821.1 - 0.066 13.0 34.8 0.65 9.7 11.1 2.5 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Flt3_lig PF02947.14 GBG86821.1 - 0.077 13.2 0.0 0.32 11.2 0.0 2.0 1 0 0 1 1 1 0 flt3 ligand Phage_Mu_Gam PF07352.12 GBG86821.1 - 0.27 11.1 14.1 0.2 11.6 4.3 2.6 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Herpes_UL6 PF01763.16 GBG86821.1 - 0.28 9.6 13.1 0.17 10.4 2.8 3.1 3 0 0 3 3 3 0 Herpesvirus UL6 like PKcGMP_CC PF16808.5 GBG86821.1 - 0.44 10.4 7.5 3.5 7.6 0.2 3.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FliD_C PF07195.12 GBG86821.1 - 0.53 9.7 6.2 1.3 8.4 6.2 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Rab5-bind PF09311.11 GBG86821.1 - 0.59 9.5 29.4 1.6 8.0 29.4 1.7 1 1 0 1 1 1 0 Rabaptin-like protein CtIP_N PF10482.9 GBG86821.1 - 0.68 10.0 25.1 0.2 11.7 7.2 3.4 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain DUF3584 PF12128.8 GBG86821.1 - 1.5 6.3 30.5 2.6 5.4 14.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 GBG86821.1 - 1.9 8.5 33.5 0.93 9.6 2.9 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein FAM76 PF16046.5 GBG86821.1 - 3 7.1 20.8 6.8 5.9 20.8 1.5 1 1 0 1 1 1 0 FAM76 protein Ntox28 PF15605.6 GBG86821.1 - 3 8.1 11.9 6.7 7.0 0.9 3.1 2 1 1 3 3 3 0 Bacterial toxin 28 Baculo_PEP_C PF04513.12 GBG86821.1 - 3.3 7.7 7.4 2.5 8.1 0.3 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 GBG86821.1 - 3.6 8.1 18.1 40 4.7 0.3 5.6 6 0 0 6 6 5 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 GBG86821.1 - 6.3 6.0 22.8 0.53 9.6 7.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 GBG86821.1 - 7.5 5.9 35.8 18 4.7 16.7 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 RVT_1 PF00078.27 GBG86822.1 - 6.4e-35 120.7 0.1 1.1e-34 120.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86822.1 - 1.3e-28 99.0 0.0 7.5e-28 96.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86822.1 - 6.5e-28 97.1 0.0 1.8e-27 95.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86822.1 - 3.1e-08 33.6 0.0 7.2e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain BTB PF00651.31 GBG86823.1 - 5.3e-14 52.4 0.0 1.2e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 GBG86823.1 - 0.049 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 SPRY domain Skp1_POZ PF03931.15 GBG86823.1 - 0.055 13.6 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Integrase_H2C2 PF17921.1 GBG86824.1 - 4.7e-14 52.2 0.4 1.1e-13 51.1 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG86824.1 - 1e-08 35.0 0.0 1.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG86824.1 - 1e-07 32.4 0.1 3.2e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86824.1 - 2.3e-05 25.0 0.0 6.8e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG86824.1 - 4.6e-05 23.7 0.0 0.00092 19.5 0.0 2.4 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86824.1 - 0.00065 19.7 0.0 0.49 10.5 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG86824.1 - 0.0073 16.1 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG86824.1 - 0.032 14.3 1.7 0.094 12.8 1.7 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2 PF09337.10 GBG86824.1 - 0.038 14.2 0.7 0.098 12.9 0.7 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Peptidase_A2E PF12382.8 GBG86824.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon peptidase Pkinase_Tyr PF07714.17 GBG86827.1 - 2.3e-21 76.2 0.0 4.7e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86827.1 - 2.2e-19 69.9 0.0 6.3e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GBG86827.1 - 4.4e-05 24.2 1.8 0.63 11.0 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat GAS PF13851.6 GBG86827.1 - 0.041 13.2 66.0 0.013 14.9 26.1 4.6 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Lip_prot_lig_C PF10437.9 GBG86827.1 - 0.92 9.5 12.7 4 7.5 0.3 4.3 4 0 0 4 4 4 0 Bacterial lipoate protein ligase C-terminus Cytochrom_B562 PF07361.11 GBG86827.1 - 3.2 8.5 21.2 1.9 9.2 5.5 4.7 2 1 1 3 3 3 0 Cytochrome b562 APG6_N PF17675.1 GBG86827.1 - 4.4 7.9 88.1 0.29 11.6 24.0 5.8 1 1 4 5 5 5 0 Apg6 coiled-coil region DUF2559 PF10832.8 GBG86827.1 - 7.1 6.8 24.1 5.3 7.2 1.1 5.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2559) WD40 PF00400.32 GBG86828.1 - 3.9e-25 87.6 20.5 7.7e-06 26.5 0.1 9.1 9 0 0 9 9 9 6 WD domain, G-beta repeat Pkinase PF00069.25 GBG86828.1 - 4.3e-21 75.5 0.0 8.2e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG86828.1 - 2.6e-19 69.5 0.0 4.8e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 GBG86828.1 - 1e-09 38.5 4.3 0.057 13.7 0.3 6.3 6 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain SHE3 PF17078.5 GBG86828.1 - 0.0057 16.4 6.0 0.0057 16.4 6.0 2.1 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 SMP PF04927.12 GBG86829.1 - 6.9e-31 106.5 22.1 1.1e-12 48.2 5.9 6.9 8 3 1 9 9 9 3 Seed maturation protein DUF4360 PF14273.6 GBG86830.1 - 3e-19 69.6 0.0 4.5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pkinase_Tyr PF07714.17 GBG86831.1 - 3.2e-23 82.3 0.0 5.7e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86831.1 - 5.2e-23 81.7 0.0 1.1e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CENP-F_leu_zip PF10473.9 GBG86831.1 - 0.00051 20.1 12.0 0.00051 20.1 12.0 2.6 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mt_ATP-synt_D PF05873.12 GBG86831.1 - 0.019 14.8 5.3 0.071 13.0 5.2 1.8 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF3086 PF11285.8 GBG86831.1 - 0.027 13.6 7.0 0.055 12.6 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Kinase-like PF14531.6 GBG86831.1 - 0.051 12.9 0.0 0.16 11.2 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Gp58 PF07902.11 GBG86831.1 - 0.14 10.4 1.5 0.2 9.9 1.5 1.1 1 0 0 1 1 1 0 gp58-like protein Exonuc_VII_L PF02601.15 GBG86831.1 - 0.17 11.5 5.5 0.28 10.7 5.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 GBG86831.1 - 0.17 9.4 11.8 0.22 9.0 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CtIP_N PF10482.9 GBG86831.1 - 0.29 11.2 9.5 0.67 10.0 1.9 2.6 1 1 2 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain DUF1664 PF07889.12 GBG86831.1 - 0.62 10.1 3.7 0.9 9.6 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 GBG86831.1 - 1 9.4 20.8 0.68 10.0 11.2 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein XhlA PF10779.9 GBG86831.1 - 1.8 8.8 3.8 22 5.4 0.6 2.8 2 0 0 2 2 2 0 Haemolysin XhlA FlaC_arch PF05377.11 GBG86831.1 - 2 8.9 7.7 0.29 11.5 1.1 2.8 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) TFIID_NTD2 PF04494.15 GBG86831.1 - 3 8.1 5.5 1.8 8.8 1.1 2.3 1 1 1 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain DUF4407 PF14362.6 GBG86831.1 - 5.1 6.4 7.4 16 4.7 7.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 GBG86831.1 - 5.8 6.2 15.2 1.3 8.3 10.5 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4706 PF15797.5 GBG86835.1 - 0.16 12.5 0.6 2.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4706) DUF4360 PF14273.6 GBG86836.1 - 8.1e-20 71.4 0.1 1.2e-19 70.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4637 PF15470.6 GBG86837.1 - 3.5 7.3 6.8 5.9 6.6 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 GBG86837.1 - 4 5.4 8.6 5.2 5.0 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RVT_1 PF00078.27 GBG86838.1 - 4.7e-49 166.9 0.2 8.7e-27 94.1 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86838.1 - 4.5e-42 142.6 0.1 9.9e-21 74.0 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86838.1 - 1.3e-38 131.1 0.0 3.8e-25 87.8 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86838.1 - 3.2e-32 110.4 3.2 5.3e-18 64.9 0.2 3.7 4 0 0 4 4 4 2 Integrase zinc binding domain rve PF00665.26 GBG86838.1 - 2.4e-23 82.6 0.0 1.9e-11 44.2 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain LRR_6 PF13516.6 GBG86838.1 - 1.1e-08 34.4 2.6 0.01 15.8 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeat zf-H2C2 PF09337.10 GBG86838.1 - 4.8e-05 23.5 0.0 0.42 10.9 0.0 3.2 3 0 0 3 3 3 2 H2C2 zinc finger Chromo PF00385.24 GBG86838.1 - 0.015 15.2 0.2 0.17 11.8 0.0 2.6 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG86838.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG86838.1 - 0.54 10.6 11.6 0.046 14.0 2.1 3.7 2 1 1 3 3 3 0 Retrotransposon gag protein IGPS PF00218.21 GBG86839.1 - 3.6e-23 82.0 0.0 5.1e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PEP_mutase PF13714.6 GBG86839.1 - 0.00014 21.4 0.8 0.00023 20.7 0.8 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ThiG PF05690.14 GBG86839.1 - 0.064 12.6 0.3 0.12 11.6 0.3 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG RT_RNaseH PF17917.1 GBG86840.1 - 4.8e-26 91.1 0.1 8.2e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86840.1 - 9.4e-25 87.4 0.0 1.7e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86840.1 - 7.1e-21 74.1 0.0 1.4e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG86840.1 - 0.12 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3653 PF12375.8 GBG86840.1 - 0.16 12.1 0.0 5 7.3 0.0 2.7 2 0 0 2 2 2 0 Phage protein RVT_1 PF00078.27 GBG86841.1 - 6.3e-51 173.0 0.0 2e-26 92.9 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86841.1 - 1.3e-25 89.4 0.0 7.1e-25 87.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86841.1 - 6.8e-24 84.2 0.0 4e-23 81.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86841.1 - 5.9e-07 30.0 0.0 2e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86841.1 - 1e-06 29.2 0.0 2.6e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG86841.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG86841.1 - 3.3e-05 24.1 1.3 0.002 18.3 0.0 3.4 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG86841.1 - 0.00046 20.0 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease HIP1_clath_bdg PF16515.5 GBG86841.1 - 0.11 13.1 11.9 0.063 13.9 8.6 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 GBG86841.1 - 1.3 9.6 2.7 1.1 9.8 0.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SSP160 PF06933.11 GBG86841.1 - 2.1 6.4 19.2 1.3 7.2 16.5 1.7 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 TPP_enzyme_N PF02776.18 GBG86842.1 - 4e-53 179.6 0.1 6.6e-53 178.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GBG86842.1 - 6.2e-44 149.1 0.0 1.1e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GBG86842.1 - 1.1e-37 129.2 1.1 4.9e-37 127.1 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain LRR_9 PF14580.6 GBG86846.1 - 6.2e-13 48.6 4.9 1.6e-09 37.5 1.2 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 GBG86846.1 - 9e-13 48.2 19.7 1.5e-05 25.2 1.5 4.2 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG86846.1 - 1.9e-09 37.2 15.0 1.2e-05 25.0 3.9 3.6 2 1 2 4 4 4 3 Leucine rich repeat zf-CCHC PF00098.23 GBG86846.1 - 0.0015 18.5 0.4 0.0057 16.7 0.4 2.1 1 0 0 1 1 1 1 Zinc knuckle LRR_6 PF13516.6 GBG86846.1 - 0.13 12.4 7.8 3.7 7.8 0.1 4.1 3 1 1 4 4 4 0 Leucine Rich repeat GDP_Man_Dehyd PF16363.5 GBG86849.1 - 6.2e-56 190.2 0.3 3.2e-55 187.9 0.3 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG86849.1 - 5.9e-50 170.0 0.0 8.4e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GBG86849.1 - 1.6e-17 63.4 0.0 5.4e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GBG86849.1 - 1.9e-13 50.2 0.0 4.9e-12 45.6 0.0 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GBG86849.1 - 1.2e-09 37.7 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GBG86849.1 - 2.9e-09 37.1 0.0 5.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GBG86849.1 - 2.6e-05 23.5 0.0 0.00042 19.6 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 GBG86849.1 - 0.00029 20.5 0.2 0.0049 16.5 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Methyltransf_25 PF13649.6 GBG86849.1 - 0.00087 19.9 0.0 0.94 10.2 0.0 2.7 3 0 0 3 3 2 2 Methyltransferase domain KR PF08659.10 GBG86849.1 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_31 PF13847.6 GBG86849.1 - 0.0044 16.8 0.0 0.62 9.9 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain adh_short PF00106.25 GBG86849.1 - 0.0059 16.1 0.1 0.0091 15.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_11 PF08241.12 GBG86849.1 - 0.0062 17.2 0.0 2.8 8.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain adh_short_C2 PF13561.6 GBG86849.1 - 0.012 15.2 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 GBG86849.1 - 0.074 12.6 0.5 0.38 10.3 0.1 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fucokinase PF07959.12 GBG86850.1 - 5.2e-66 223.3 0.0 1.3e-26 93.6 0.0 4.0 4 0 0 4 4 4 4 L-fucokinase GHMP_kinases_N PF00288.26 GBG86850.1 - 1.7e-08 34.6 1.1 7.5e-08 32.5 0.1 2.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GBG86850.1 - 0.0046 17.3 0.1 0.0046 17.3 0.1 3.1 3 0 0 3 3 3 1 GHMP kinases C terminal Presenilin PF01080.17 GBG86851.1 - 0.0037 16.1 1.5 0.0045 15.8 1.5 1.1 1 0 0 1 1 1 1 Presenilin PPP4R2 PF09184.11 GBG86851.1 - 0.45 10.1 19.1 0.61 9.6 19.1 1.1 1 0 0 1 1 1 0 PPP4R2 GCD14 PF08704.10 GBG86851.1 - 4 7.0 4.9 8.7 5.9 0.2 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DUF3362 PF11842.8 GBG86851.1 - 5.2 7.4 9.0 1.6 9.1 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) MRNIP PF15749.5 GBG86851.1 - 7.2 7.4 15.5 7.8 7.3 6.8 2.3 2 0 0 2 2 2 0 MRN-interacting protein NUDIX PF00293.28 GBG86852.1 - 8.2e-05 22.7 3.4 8.2e-05 22.7 3.4 1.8 2 0 0 2 2 2 1 NUDIX domain DUF913 PF06025.12 GBG86852.1 - 0.57 9.1 3.2 0.83 8.6 3.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 GBG86852.1 - 2.2 8.0 18.9 0.34 10.7 14.8 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PA26 PF04636.13 GBG86852.1 - 5.4 5.8 7.5 8 5.3 7.5 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) WD40 PF00400.32 GBG86853.1 - 8.7e-34 115.0 15.2 5.5e-08 33.3 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG86853.1 - 4.6e-10 39.7 0.5 0.097 13.0 0.0 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG86853.1 - 0.00015 21.7 0.6 0.16 11.9 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PRIMA1 PF16101.5 GBG86853.1 - 0.16 12.0 5.3 0.34 11.0 5.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG86853.1 - 0.18 11.3 9.2 0.39 10.2 9.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SpoIIIAH PF12685.7 GBG86853.1 - 0.53 10.1 5.9 0.097 12.5 0.8 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein SDA1 PF05285.12 GBG86853.1 - 6.7 6.0 27.3 0.13 11.6 17.4 2.0 2 0 0 2 2 2 0 SDA1 DUF2052 PF09747.9 GBG86854.1 - 0.00018 21.7 1.1 0.00021 21.5 1.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF4746 PF15928.5 GBG86854.1 - 0.013 14.9 1.1 0.015 14.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 GBG86854.1 - 0.16 11.3 0.8 0.17 11.2 0.8 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GBG86854.1 - 0.64 8.2 2.4 0.85 7.8 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Phage_Gp23 PF10669.9 GBG86854.1 - 1.2 9.5 4.7 1.7 9.0 4.7 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DNA_pol_phi PF04931.13 GBG86854.1 - 1.4 6.9 7.1 1.8 6.6 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 GBG86854.1 - 3.4 6.6 12.1 4.7 6.1 12.1 1.1 1 0 0 1 1 1 0 Paf1 ArgoL1 PF08699.10 GBG86855.1 - 1.1e-12 47.4 0.7 2.3e-12 46.4 0.7 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 GBG86855.1 - 1.4e-11 45.1 0.0 1.8e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of argonaute RVT_1 PF00078.27 GBG86856.1 - 6.6e-27 94.5 0.1 1.1e-26 93.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86857.1 - 4.4e-27 94.0 0.0 8.5e-27 93.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86857.1 - 9.4e-24 83.7 0.0 1.6e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86857.1 - 1e-19 70.4 0.2 2.4e-19 69.2 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86857.1 - 0.046 14.0 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG86858.1 - 3.8e-05 24.2 0.0 0.00013 22.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86858.1 - 9.7e-05 22.9 0.0 0.00036 21.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG86858.1 - 0.00053 20.2 4.7 0.0028 17.9 0.1 3.5 3 1 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG86858.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86858.1 - 0.0034 17.2 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease GIT_CC PF16559.5 GBG86858.1 - 5.2 7.0 6.9 9.3 6.2 0.1 3.6 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Nop14 PF04147.12 GBG86859.1 - 0.032 12.4 63.4 0.041 12.1 63.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF5523 PF17661.1 GBG86859.1 - 0.79 9.4 58.7 1.3 8.6 58.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Asp_protease_2 PF13650.6 GBG86862.1 - 2e-07 31.5 0.1 4.4e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86862.1 - 2.6e-05 24.7 0.1 5.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG86862.1 - 0.025 14.4 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG86862.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease AHH PF14412.6 GBG86862.1 - 0.11 12.6 0.0 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Prothymosin PF03247.14 GBG86862.1 - 9 6.8 22.2 1.5 9.3 11.5 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family Integrase_H2C2 PF17921.1 GBG86863.1 - 3.5e-28 97.5 3.6 5e-14 52.1 0.1 2.5 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG86863.1 - 3.2e-10 40.3 0.0 2.2e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG86863.1 - 0.0021 18.3 0.9 0.44 10.8 0.0 2.6 2 0 0 2 2 2 2 H2C2 zinc finger DivIC PF04977.15 GBG86863.1 - 5.1 7.0 7.4 1 9.1 0.9 2.9 2 0 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 GBG86863.1 - 8.3 6.5 8.1 1 9.4 2.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) RNA_pol_Rpb1_1 PF04997.12 GBG86864.1 - 4e-116 387.7 0.6 7e-116 386.9 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GBG86864.1 - 1.9e-106 355.4 0.0 2.8e-106 354.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GBG86864.1 - 3.8e-72 241.9 0.2 1.2e-71 240.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 GBG86864.1 - 4.7e-63 212.5 0.1 1.3e-62 211.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 GBG86864.1 - 8e-54 181.3 4.8 1.7e-53 180.2 4.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 GBG86864.1 - 1.5e-48 164.7 0.0 3.1e-48 163.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GBG86864.1 - 5.5e-40 135.7 0.7 1.6e-39 134.2 0.7 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 GBG86864.1 - 1.8e-28 97.3 603.5 0.022 15.1 14.0 30.7 26 3 6 33 33 33 26 RNA polymerase Rpb1 C-terminal repeat DUF659 PF04937.15 GBG86865.1 - 1.9e-20 73.3 0.1 2.3e-11 43.8 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG86865.1 - 1.7e-08 34.1 0.1 3.6e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Yippee-Mis18 PF03226.14 GBG86866.1 - 1.8e-14 53.8 0.2 2.1e-14 53.6 0.2 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 GBG86866.1 - 0.02 15.1 0.3 0.027 14.7 0.3 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I zf-HIT PF04438.16 GBG86866.1 - 0.18 11.7 4.1 1.8 8.5 0.6 2.4 2 0 0 2 2 2 0 HIT zinc finger Cpn60_TCP1 PF00118.24 GBG86867.1 - 7.3e-156 519.6 0.4 8.3e-156 519.4 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RT_RNaseH PF17917.1 GBG86868.1 - 3.7e-30 104.3 0.5 2.1e-29 101.9 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86868.1 - 3.8e-29 100.7 0.0 1.5e-28 98.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86868.1 - 2.3e-18 66.1 0.7 4.7e-18 65.0 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86868.1 - 2.4e-17 63.2 0.0 1.1e-16 61.1 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG86868.1 - 0.0016 18.6 0.1 0.0038 17.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG86869.1 - 3.9e-59 196.9 0.0 9.2e-30 102.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86869.1 - 2.9e-55 187.2 0.4 2.6e-33 115.4 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86869.1 - 2e-47 159.8 0.3 6.7e-26 90.6 0.1 3.0 2 1 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86869.1 - 1e-15 58.0 0.0 2.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG86869.1 - 7.9e-14 51.5 0.2 7.3e-13 48.4 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86869.1 - 0.0019 18.3 0.0 0.0056 16.9 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG86869.1 - 0.12 12.6 0.0 0.62 10.4 0.0 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein eIF-1a PF01176.19 GBG86869.1 - 0.13 12.1 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 HALZ PF02183.18 GBG86869.1 - 0.15 12.3 0.6 0.53 10.5 0.6 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF5095 PF17016.5 GBG86869.1 - 0.54 9.9 2.5 2.5 7.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) Phage_GPO PF05929.11 GBG86869.1 - 4.7 6.7 5.1 6.4 6.3 0.1 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase bZIP_2 PF07716.15 GBG86869.1 - 7.7 6.7 8.5 2.9 8.0 1.5 2.7 2 0 0 2 2 2 0 Basic region leucine zipper TMF_DNA_bd PF12329.8 GBG86870.1 - 0.0055 16.7 7.5 0.0055 16.7 7.5 7.0 5 2 3 8 8 8 3 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 GBG86870.1 - 0.042 14.3 75.9 0.078 13.4 18.6 4.9 2 1 3 5 5 5 0 Fez1 Laminin_II PF06009.12 GBG86870.1 - 0.053 13.5 0.2 0.053 13.5 0.2 5.7 2 1 3 6 6 6 0 Laminin Domain II Gas_vesicle_C PF01304.17 GBG86870.1 - 0.61 10.1 13.4 0.035 14.1 3.8 3.0 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain DUF1796 PF08795.10 GBG86870.1 - 1.2 9.0 11.5 0.25 11.3 0.9 3.4 1 1 2 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) MWFE PF15879.5 GBG86870.1 - 1.5 9.0 3.7 28 5.0 0.3 2.8 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Takusan PF04822.13 GBG86870.1 - 4.3 7.3 13.8 0.96 9.4 1.1 3.7 3 0 0 3 3 3 0 Takusan DUF3584 PF12128.8 GBG86870.1 - 9 3.7 62.1 2.2 5.7 20.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Integrase_H2C2 PF17921.1 GBG86872.1 - 9.9e-18 64.0 0.0 2.2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86872.1 - 2.2e-12 47.2 0.0 4.4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG86872.1 - 0.0075 16.5 0.0 0.024 14.8 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG86873.1 - 6.8e-34 115.9 0.1 1.5e-33 114.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86873.1 - 8.6e-29 99.9 0.1 1.8e-28 98.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86873.1 - 8.5e-19 67.4 0.3 2.4e-18 66.0 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86873.1 - 1.2e-15 57.7 0.0 2.9e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain SDA1 PF05285.12 GBG86873.1 - 6.7e-05 22.5 6.8 0.00011 21.7 6.8 1.2 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 GBG86873.1 - 0.00029 19.4 7.1 0.00043 18.9 7.1 1.1 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.14 GBG86873.1 - 0.00046 18.6 6.7 0.00072 18.0 6.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Na_trans_assoc PF06512.13 GBG86873.1 - 0.0026 18.1 0.1 0.0054 17.0 0.1 1.5 1 0 0 1 1 1 1 Sodium ion transport-associated RNA_pol_3_Rpc31 PF11705.8 GBG86873.1 - 0.004 17.4 11.8 0.012 15.9 11.8 1.8 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 YL1 PF05764.13 GBG86873.1 - 0.0043 17.2 12.1 0.0076 16.4 12.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein BUD22 PF09073.10 GBG86873.1 - 0.017 14.5 8.2 0.027 13.8 8.2 1.2 1 0 0 1 1 1 0 BUD22 zf-CCHC_3 PF13917.6 GBG86873.1 - 0.019 14.9 2.3 0.045 13.7 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle GP120 PF00516.18 GBG86873.1 - 0.023 13.3 0.1 0.044 12.4 0.1 1.3 1 0 0 1 1 1 0 Envelope glycoprotein GP120 DARPP-32 PF05395.12 GBG86873.1 - 0.038 14.2 7.4 0.074 13.3 7.4 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Retrotrans_gag PF03732.17 GBG86873.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG86873.1 - 0.15 12.3 2.0 0.21 11.8 0.0 2.4 2 0 0 2 2 1 0 H2C2 zinc finger DUF3391 PF11871.8 GBG86873.1 - 0.22 12.0 2.9 0.7 10.4 2.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Presenilin PF01080.17 GBG86873.1 - 0.28 9.9 0.6 0.39 9.4 0.6 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG86873.1 - 0.38 8.9 18.3 0.7 8.0 18.3 1.3 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 GBG86873.1 - 1.4 8.7 6.1 4.8 7.0 6.1 2.0 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.13 GBG86873.1 - 2.5 7.9 13.8 0.67 9.8 10.0 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region PPP4R2 PF09184.11 GBG86873.1 - 3.7 7.1 14.7 6.2 6.3 14.7 1.3 1 0 0 1 1 1 0 PPP4R2 DUF2201_N PF13203.6 GBG86873.1 - 6.9 6.2 9.2 17 4.9 9.2 1.6 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF647 PF04884.14 GBG86874.1 - 5.8e-70 235.7 0.1 7.8e-70 235.2 0.1 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis NDUF_B5 PF09781.9 GBG86874.1 - 0.029 13.9 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit SNARE_assoc PF09335.11 GBG86876.1 - 4.1e-27 95.1 10.1 4.1e-27 95.1 10.1 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein Macoilin PF09726.9 GBG86876.1 - 0.056 12.0 8.1 0.067 11.8 8.1 1.1 1 0 0 1 1 1 0 Macoilin family Med13_C PF06333.12 GBG86876.1 - 0.59 9.3 10.2 0.91 8.7 10.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain SOG2 PF10428.9 GBG86876.1 - 1.7 7.8 20.6 2.3 7.3 20.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Spt5_N PF11942.8 GBG86876.1 - 1.7 9.6 10.8 2.4 9.2 5.1 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FYDLN_acid PF09538.10 GBG86876.1 - 2.2 9.0 11.8 0.61 10.8 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Utp14 PF04615.13 GBG86876.1 - 8.5 4.8 17.8 11 4.5 17.8 1.0 1 0 0 1 1 1 0 Utp14 protein DnaJ PF00226.31 GBG86877.1 - 1.8e-15 56.8 0.1 3e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 GBG86879.1 - 4.5e-21 74.4 0.0 5.7e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG86879.1 - 0.00082 19.4 0.0 0.0021 18.1 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 GBG86880.1 - 4.9e-22 77.5 0.0 6.3e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG86880.1 - 0.0002 21.4 0.0 0.00039 20.5 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif SIR2 PF02146.17 GBG86885.1 - 4.6e-46 157.0 0.0 6.7e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GBG86885.1 - 0.14 11.9 0.1 10 5.8 0.0 3.0 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain CAP_N PF01213.19 GBG86885.1 - 1.2 8.6 7.6 3.3 7.1 7.6 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG86885.1 - 3.3 7.8 15.8 0.38 10.8 9.4 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RT_RNaseH_2 PF17919.1 GBG86887.1 - 8.2e-32 109.2 0.0 1.6e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86887.1 - 2.6e-26 91.9 0.0 5.1e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86887.1 - 1.3e-19 70.6 0.0 2.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86887.1 - 8.8e-19 67.4 0.1 2e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86887.1 - 3.5e-15 56.2 0.0 1e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_4 PF14392.6 GBG86887.1 - 0.0067 16.1 0.1 0.021 14.6 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 GBG86887.1 - 0.0077 16.4 0.0 0.025 14.8 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_6 PF15288.6 GBG86887.1 - 0.016 15.0 1.3 0.039 13.8 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG86887.1 - 0.32 11.1 3.2 0.74 10.0 3.2 1.6 1 0 0 1 1 1 0 Zinc knuckle CLP1_P PF16575.5 GBG86888.1 - 3.4e-69 232.4 0.0 4.9e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 GBG86888.1 - 1.2e-30 105.6 0.0 3.3e-30 104.2 0.0 1.7 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 GBG86888.1 - 2.4e-28 98.9 0.0 4.2e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 GBG86888.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 GBG86888.1 - 0.039 14.3 0.0 0.1 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 GBG86888.1 - 0.14 12.3 0.0 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.7 GBG86888.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.10 GBG86888.1 - 0.15 11.5 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_35 PF14516.6 GBG86888.1 - 0.18 10.6 0.0 1.1 8.0 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain DDE_Tnp_4 PF13359.6 GBG86889.1 - 2.9e-25 88.8 0.0 4.6e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86889.1 - 3.3e-08 33.4 0.0 5.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Herpes_BLLF1 PF05109.13 GBG86889.1 - 2.7 5.8 6.0 4.4 5.1 6.0 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) RT_RNaseH_2 PF17919.1 GBG86890.1 - 5.6e-21 74.5 0.0 1.7e-20 72.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86890.1 - 3.4e-19 69.1 0.0 8.4e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86890.1 - 4.5e-14 52.7 0.4 1.5e-13 51.0 0.0 2.1 2 0 0 2 2 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86890.1 - 2.2e-08 34.5 0.0 7.7e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86890.1 - 1e-05 26.1 0.0 3.1e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Tudor-knot PF11717.8 GBG86890.1 - 0.00078 19.3 0.0 0.0025 17.7 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF1758 PF05585.12 GBG86890.1 - 0.0069 16.2 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Chromo PF00385.24 GBG86890.1 - 0.027 14.4 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG86890.1 - 0.031 14.1 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease TOBE_2 PF08402.10 GBG86890.1 - 0.069 13.3 0.6 1.6 8.9 0.0 2.9 3 0 0 3 3 2 0 TOBE domain Retrotrans_gag PF03732.17 GBG86890.1 - 0.13 12.6 0.8 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein RVP_2 PF08284.11 GBG86890.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease TraC PF07820.12 GBG86890.1 - 0.43 10.9 9.7 0.12 12.7 0.4 3.2 3 0 0 3 3 2 0 TraC-like protein CstA PF02554.14 GBG86890.1 - 0.8 8.5 3.1 79 2.0 0.0 3.7 3 2 2 5 5 5 0 Carbon starvation protein CstA XendoU PF09412.10 GBG86890.1 - 1.2 8.3 6.8 5.3 6.2 0.7 2.4 1 1 1 2 2 2 0 Endoribonuclease XendoU Radical_SAM PF04055.21 GBG86891.1 - 4.1e-26 92.4 0.0 7.1e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 GBG86891.1 - 8.2e-25 86.9 0.0 1.6e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Wyosine base formation CMD PF02627.20 GBG86891.1 - 0.08 13.0 1.1 1.7 8.7 0.5 2.6 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Radical_SAM PF04055.21 GBG86892.1 - 3.1e-26 92.7 0.0 5.7e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 GBG86892.1 - 6.9e-25 87.2 0.0 1.3e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Wyosine base formation CMD PF02627.20 GBG86892.1 - 0.062 13.3 1.1 1.5 8.9 0.5 2.6 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family DUF4164 PF13747.6 GBG86894.1 - 0.013 15.8 2.2 0.044 14.1 2.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Ribosomal_S30AE PF02482.19 GBG86894.1 - 0.068 14.0 0.3 0.19 12.5 0.0 1.8 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF4407 PF14362.6 GBG86895.1 - 0.097 12.0 10.7 0.027 13.8 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG86896.1 - 5.6e-25 88.2 0.0 8.4e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86896.1 - 3.6e-24 84.7 0.0 8.8e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86896.1 - 6.8e-14 52.0 0.0 1.7e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86897.1 - 3.2e-25 88.9 0.0 5.1e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86897.1 - 2.7e-24 85.1 0.0 5.8e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86897.1 - 2e-17 63.0 0.3 6.5e-17 61.4 0.0 2.1 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG86897.1 - 5.2e-14 52.4 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG86897.1 - 0.068 13.4 0.0 0.3 11.4 0.0 2.2 1 0 0 1 1 1 0 H2C2 zinc finger DUF4956 PF16316.5 GBG86897.1 - 0.39 10.4 0.8 1.5 8.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) Thioredoxin PF00085.20 GBG86898.1 - 1.3e-63 211.4 0.1 1.5e-32 111.6 0.1 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 GBG86898.1 - 9.1e-11 42.2 1.1 0.00065 20.1 0.2 3.7 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GBG86898.1 - 1e-09 38.6 0.0 0.0014 18.9 0.0 3.9 2 2 1 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 GBG86898.1 - 2.4e-09 37.0 0.0 0.00061 19.2 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GBG86898.1 - 3.1e-08 33.7 0.1 0.0034 17.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.6 GBG86898.1 - 2.3e-05 24.4 0.0 0.022 14.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.21 GBG86898.1 - 3.8e-05 23.6 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_5 PF13743.6 GBG86898.1 - 0.00088 19.0 0.9 0.22 11.2 0.0 3.5 2 2 1 4 4 4 1 Thioredoxin Thioredoxin_6 PF13848.6 GBG86898.1 - 0.0012 18.8 0.0 0.62 9.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain ERp29_N PF07912.13 GBG86898.1 - 0.0015 18.6 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.6 GBG86898.1 - 0.0025 18.0 1.5 10 6.2 0.1 3.8 2 2 2 4 4 4 0 Thioredoxin Thioredoxin_9 PF14595.6 GBG86898.1 - 0.0032 17.2 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.20 GBG86898.1 - 0.0052 16.6 0.4 5.7 6.7 0.0 3.7 2 2 2 4 4 4 1 DSBA-like thioredoxin domain DIM1 PF02966.16 GBG86898.1 - 0.0069 16.2 0.0 0.079 12.7 0.0 2.1 2 0 0 2 2 2 1 Mitosis protein DIM1 Glutaredoxin PF00462.24 GBG86898.1 - 0.011 16.0 0.7 0.81 10.0 0.1 2.6 2 1 0 2 2 2 0 Glutaredoxin TraF PF13728.6 GBG86898.1 - 0.017 15.0 0.1 0.83 9.4 0.0 2.4 2 1 0 2 2 2 0 F plasmid transfer operon protein Redoxin PF08534.10 GBG86898.1 - 0.049 13.3 0.9 1.9 8.2 0.4 2.3 2 1 0 2 2 2 0 Redoxin HyaE PF07449.11 GBG86898.1 - 0.12 12.3 0.0 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE ALAD PF00490.21 GBG86898.1 - 0.12 11.5 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 Delta-aminolevulinic acid dehydratase RT_RNaseH_2 PF17919.1 GBG86899.1 - 3.2e-53 177.9 0.0 6.8e-26 90.2 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86899.1 - 4e-50 168.5 0.0 2.5e-24 85.6 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86899.1 - 1.5e-26 92.3 1.5 4.8e-16 58.6 0.1 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG86899.1 - 2.9e-23 82.6 0.0 5.7e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG86899.1 - 7e-12 45.6 0.0 2e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG86899.1 - 0.0054 17.0 0.1 0.0054 17.0 0.1 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein ubiquitin PF00240.23 GBG86899.1 - 0.029 14.1 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin family ST7 PF04184.12 GBG86899.1 - 0.097 11.1 0.6 12 4.3 0.0 2.7 2 0 0 2 2 2 0 ST7 protein TAXi_C PF14541.6 GBG86899.1 - 0.13 12.0 0.0 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal AAA_12 PF13087.6 GBG86902.1 - 5.4e-31 107.8 0.0 1.1e-30 106.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG86902.1 - 1e-10 41.9 0.1 1.9e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG86902.1 - 0.0031 17.3 0.0 0.0088 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain LPP20 PF02169.16 GBG86903.1 - 0.43 10.9 5.8 0.45 10.9 4.8 1.5 1 1 0 1 1 1 0 LPP20 lipoprotein V_ATPase_I PF01496.19 GBG86903.1 - 1.4 6.7 9.5 1.8 6.3 9.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XRN_M PF17846.1 GBG86903.1 - 3.3 6.5 8.1 4.7 6.1 8.1 1.3 1 0 0 1 1 1 0 Xrn1 helical domain TFIIF_alpha PF05793.12 GBG86904.1 - 0.96 8.0 44.0 0.01 14.5 36.5 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3562 PF12085.8 GBG86906.1 - 0.31 10.7 1.7 0.36 10.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) N6_N4_Mtase PF01555.18 GBG86908.1 - 6.7e-06 26.0 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 DNA methylase FAM176 PF14851.6 GBG86908.1 - 0.094 12.4 3.4 0.2 11.3 3.4 1.5 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 GBG86908.1 - 0.47 9.8 8.6 0.78 9.1 8.6 1.3 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 GBG86908.1 - 1.9 8.3 8.3 3.6 7.4 8.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 GBG86908.1 - 2 6.5 12.3 2.9 6.0 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 GBG86908.1 - 2.2 7.6 10.5 3.6 6.9 10.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.10 GBG86908.1 - 2.6 8.5 10.9 7.8 7.0 10.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.16 GBG86908.1 - 5.2 6.2 5.5 8.8 5.4 5.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit AAA_11 PF13086.6 GBG86909.1 - 3.8e-24 85.9 2.0 7.3e-11 42.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 GBG86909.1 - 3.3e-13 49.8 0.0 6e-11 42.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GBG86909.1 - 6e-10 39.6 0.0 1.6e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 GBG86909.1 - 0.00022 20.9 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 GBG86909.1 - 0.0008 19.8 0.6 0.0026 18.2 0.6 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GBG86909.1 - 0.0019 18.2 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 GBG86909.1 - 0.0073 16.1 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 GBG86909.1 - 0.017 15.5 0.2 0.044 14.2 0.2 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GBG86909.1 - 0.049 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 GBG86909.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain zf-CCHC PF00098.23 GBG86911.1 - 6.4e-06 26.0 1.5 6.4e-06 26.0 1.5 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG86911.1 - 0.088 12.6 0.5 0.16 11.7 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86911.1 - 0.13 12.1 0.9 0.2 11.5 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG86911.1 - 0.16 11.8 2.0 0.75 9.7 1.9 2.1 1 1 1 2 2 2 0 Zinc knuckle AbiH PF14253.6 GBG86911.1 - 0.57 10.0 6.0 0.84 9.4 6.0 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF2400 PF09674.10 GBG86911.1 - 0.76 9.7 4.2 1.3 9.0 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) PA26 PF04636.13 GBG86911.1 - 1.3 7.9 4.8 1.8 7.4 4.8 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HAD PF12710.7 GBG86911.1 - 2 8.8 3.9 1.4 9.3 2.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Rx_N PF18052.1 GBG86911.1 - 4.3 7.7 12.1 0.65 10.3 2.5 3.1 3 0 0 3 3 3 0 Rx N-terminal domain V_ATPase_I PF01496.19 GBG86911.1 - 6.2 4.6 10.9 9.2 4.0 10.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WDCP PF15390.6 GBG86911.1 - 8.9 4.6 6.7 13 4.1 6.7 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Presenilin PF01080.17 GBG86911.1 - 9 4.9 8.2 12 4.6 8.2 1.1 1 0 0 1 1 1 0 Presenilin AAA_12 PF13087.6 GBG86912.1 - 8.4e-47 159.4 0.0 1.2e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG86912.1 - 6e-24 85.2 0.2 3.1e-11 43.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 GBG86912.1 - 5.1e-11 42.6 0.0 1.6e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG86912.1 - 2.4e-10 40.9 0.0 1.8e-09 38.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GBG86912.1 - 0.00012 21.9 0.2 1.4 8.6 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 GBG86912.1 - 0.0012 18.7 0.1 1.2 9.0 0.0 3.0 2 1 0 2 2 2 2 Helicase AAA PF00004.29 GBG86912.1 - 0.0017 18.8 0.9 0.0074 16.7 0.9 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GBG86912.1 - 0.0096 15.9 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 GBG86912.1 - 0.011 15.5 0.0 0.043 13.7 0.0 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 GBG86912.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 GBG86912.1 - 0.075 13.4 0.2 0.26 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GBG86912.1 - 0.16 12.3 0.0 0.52 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG86912.1 - 0.19 12.2 0.3 6.7 7.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 GBG86912.1 - 0.22 11.1 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Aminotran_1_2 PF00155.21 GBG86913.1 - 6.7e-84 282.1 0.0 7.9e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 GBG86914.1 - 6.7e-84 282.1 0.0 8e-84 281.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RVT_1 PF00078.27 GBG86917.1 - 8e-29 100.7 0.0 1.2e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG86917.1 - 0.00055 20.3 0.8 0.0021 18.4 0.8 2.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain APG17 PF04108.12 GBG86917.1 - 0.0008 18.6 0.2 0.023 13.8 0.0 2.1 2 0 0 2 2 2 1 Autophagy protein Apg17 DDE_Tnp_4 PF13359.6 GBG86918.1 - 1.2e-22 80.3 0.0 1.5e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86918.1 - 7e-13 48.6 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG86918.1 - 0.061 13.0 0.0 0.22 11.1 0.0 1.8 2 1 0 2 2 2 0 Transposase DDE domain RT_RNaseH PF17917.1 GBG86919.1 - 5.3e-31 107.0 0.2 1.7e-30 105.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86919.1 - 1.3e-29 102.2 0.0 3.3e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86919.1 - 1.1e-19 70.2 1.2 2e-19 69.4 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86919.1 - 0.0003 20.9 0.1 0.0011 19.1 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger PAS_4 PF08448.10 GBG86919.1 - 0.13 12.5 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 PAS fold Phage_GPO PF05929.11 GBG86919.1 - 0.26 10.9 0.0 0.26 10.9 0.0 2.9 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Es2 PF09751.9 GBG86919.1 - 3.1 7.4 16.2 4.7 6.8 16.2 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 Vps62 PF06101.11 GBG86920.1 - 3.7e-25 88.3 0.0 1.8e-16 59.6 0.0 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 62 Toxin_10 PF05431.11 GBG86920.1 - 2.7e-07 30.2 0.1 5.2e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Insecticidal Crystal Toxin, P42 DDE_Tnp_ISAZ013 PF07592.11 GBG86920.1 - 0.012 14.6 0.4 0.019 14.0 0.4 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DUF4131 PF13567.6 GBG86920.1 - 0.14 11.8 0.0 4.6 6.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Pkinase_Tyr PF07714.17 GBG86922.1 - 7.8e-14 51.6 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86922.1 - 4.6e-11 42.6 0.0 6.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Retrotrans_gag PF03732.17 GBG86924.1 - 0.0047 17.2 0.7 0.084 13.2 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Phage_lysozyme PF00959.19 GBG86924.1 - 0.14 12.6 0.1 0.56 10.7 0.0 2.0 2 0 0 2 2 2 0 Phage lysozyme HisKA PF00512.25 GBG86924.1 - 6.7 6.8 8.5 7.4 6.7 0.8 3.4 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain RAP1 PF07218.11 GBG86925.1 - 6.5 4.9 11.1 12 4.1 11.1 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) F-box-like PF12937.7 GBG86926.1 - 6.7e-05 22.7 0.1 0.00018 21.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 GBG86927.1 - 5.6e-05 22.9 0.1 0.00015 21.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Integrase_H2C2 PF17921.1 GBG86928.1 - 2.8e-20 72.2 1.3 4.2e-20 71.6 0.4 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG86928.1 - 0.00023 21.3 0.1 0.00045 20.4 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Phage_HK97_TLTM PF06120.11 GBG86928.1 - 0.024 13.8 3.4 0.034 13.3 3.4 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DUF1690 PF07956.11 GBG86928.1 - 8.5 6.8 10.5 3.1 8.2 6.6 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) RVT_1 PF00078.27 GBG86929.1 - 1e-27 97.1 0.0 5.1e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG86929.1 - 0.00075 19.7 0.1 0.0068 16.7 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein APG17 PF04108.12 GBG86929.1 - 0.031 13.4 0.2 0.15 11.1 0.0 2.0 2 1 0 2 2 2 0 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG86930.1 - 1.7e-26 92.1 0.0 6.1e-26 90.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86930.1 - 2.4e-23 82.8 0.1 4.2e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86930.1 - 3.8e-23 81.8 0.0 1.4e-22 79.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG86930.1 - 4.9e-08 32.7 1.6 1.1e-07 31.5 1.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG86930.1 - 0.0021 17.8 1.9 0.0058 16.4 1.9 1.8 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG86930.1 - 0.0041 17.6 0.0 0.012 16.2 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Spore_coat_CotO PF14153.6 GBG86930.1 - 0.48 10.3 6.5 4 7.3 1.7 2.3 2 0 0 2 2 2 0 Spore coat protein CotO DDE_Tnp_4 PF13359.6 GBG86931.1 - 4.9e-32 110.8 0.0 1.8e-31 109.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86931.1 - 1.1e-15 57.8 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG86931.1 - 9.2e-05 22.2 1.6 0.07 12.8 0.3 3.1 2 1 0 2 2 2 1 Transposase DDE domain zf-RanBP PF00641.18 GBG86931.1 - 2.9 7.3 6.8 15 5.0 0.6 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others RVT_1 PF00078.27 GBG86933.1 - 1.8e-34 119.2 0.0 2.9e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86933.1 - 1.5e-30 105.2 0.0 4.3e-30 103.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86933.1 - 2.2e-30 105.0 0.1 4.2e-30 104.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PseudoU_synth_1 PF01416.20 GBG86933.1 - 3.5e-10 40.3 0.0 5.9e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase RVP_2 PF08284.11 GBG86933.1 - 5.2e-07 29.5 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86933.1 - 5.3e-05 23.8 0.0 0.00012 22.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86933.1 - 0.0011 19.5 0.0 0.0028 18.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG86933.1 - 0.004 17.4 0.0 0.016 15.5 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG86933.1 - 0.0085 16.2 3.9 0.02 15.0 3.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86933.1 - 0.019 15.2 0.1 0.25 11.5 0.0 2.6 2 0 0 2 2 2 0 Integrase core domain Asp_protease PF09668.10 GBG86933.1 - 0.047 13.5 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease PNMA PF14893.6 GBG86933.1 - 0.064 12.6 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 PNMA Phage_lysozyme PF00959.19 GBG86933.1 - 0.085 13.3 0.0 0.32 11.4 0.0 2.0 1 0 0 1 1 1 0 Phage lysozyme DUF1758 PF05585.12 GBG86933.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG86934.1 - 1.8e-34 119.2 0.0 2.9e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86934.1 - 1.5e-30 105.2 0.0 4.3e-30 103.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86934.1 - 2.2e-30 105.0 0.1 4.2e-30 104.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PseudoU_synth_1 PF01416.20 GBG86934.1 - 3.5e-10 40.3 0.0 5.9e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase RVP_2 PF08284.11 GBG86934.1 - 5.2e-07 29.5 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG86934.1 - 5.3e-05 23.8 0.0 0.00012 22.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86934.1 - 0.0011 19.5 0.0 0.0028 18.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG86934.1 - 0.004 17.4 0.0 0.016 15.5 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG86934.1 - 0.0085 16.2 3.9 0.02 15.0 3.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86934.1 - 0.019 15.2 0.1 0.25 11.5 0.0 2.6 2 0 0 2 2 2 0 Integrase core domain Asp_protease PF09668.10 GBG86934.1 - 0.044 13.6 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease PNMA PF14893.6 GBG86934.1 - 0.064 12.6 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 PNMA Phage_lysozyme PF00959.19 GBG86934.1 - 0.085 13.3 0.0 0.32 11.4 0.0 2.0 1 0 0 1 1 1 0 Phage lysozyme DUF1758 PF05585.12 GBG86934.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DBD_Tnp_Mut PF03108.15 GBG86935.1 - 1.4e-15 57.0 0.1 1.4e-15 57.0 0.1 2.1 2 0 0 2 2 2 1 MuDR family transposase MULE PF10551.9 GBG86935.1 - 1.3e-14 54.4 0.0 5.2e-14 52.4 0.0 2.2 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 GBG86935.1 - 6.7e-07 28.9 0.6 1.7e-06 27.6 0.6 1.7 1 0 0 1 1 1 1 SWIM zinc finger Myb_DNA-bind_4 PF13837.6 GBG86936.1 - 4.2e-06 27.0 1.0 4.2e-06 27.0 1.0 2.4 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG86937.1 - 7.3e-15 55.0 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86937.1 - 0.00032 20.4 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein RepA_C PF04796.12 GBG86937.1 - 0.0032 17.5 0.0 0.27 11.3 0.0 2.2 2 0 0 2 2 2 1 Plasmid encoded RepA protein Beach PF02138.18 GBG86937.1 - 0.23 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Beige/BEACH domain DUF615 PF04751.14 GBG86938.1 - 6.3e-20 71.7 0.9 9.6e-20 71.1 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF615) zf-RING_2 PF13639.6 GBG86939.1 - 3.5e-09 36.9 7.1 1.6e-08 34.7 7.1 2.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG86939.1 - 2.5e-07 30.4 7.2 2.5e-07 30.4 7.2 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG86939.1 - 2.7e-06 27.3 7.5 7.6e-06 25.8 7.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GBG86939.1 - 8.9e-06 25.5 3.8 8.9e-06 25.5 3.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG86939.1 - 1.7e-05 24.6 7.1 1.7e-05 24.6 7.1 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG86939.1 - 8e-05 22.5 5.5 8e-05 22.5 5.5 2.5 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GBG86939.1 - 0.00051 20.1 7.7 0.0018 18.4 7.7 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING PI3_PI4_kinase PF00454.27 GBG86939.1 - 0.0052 16.6 0.1 0.34 10.7 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase LXG PF04740.12 GBG86939.1 - 0.18 11.5 4.0 0.072 12.8 1.3 1.7 2 0 0 2 2 2 0 LXG domain of WXG superfamily Phage_GPO PF05929.11 GBG86939.1 - 0.5 9.9 2.3 1 8.9 2.3 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.11 GBG86939.1 - 0.55 9.1 8.4 0.92 8.3 8.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 GBG86939.1 - 0.65 9.2 7.8 1.2 8.3 7.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein Blo-t-5 PF11642.8 GBG86939.1 - 0.75 9.8 7.0 0.97 9.4 0.1 2.6 3 0 0 3 3 3 0 Mite allergen Blo t 5 SlyX PF04102.12 GBG86939.1 - 0.96 10.1 10.8 0.14 12.8 2.6 3.1 2 1 1 3 3 3 0 SlyX OmpH PF03938.14 GBG86939.1 - 1 9.7 6.1 2 8.8 6.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 GBG86939.1 - 1.2 9.4 6.6 2.4 8.5 0.3 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prok-RING_4 PF14447.6 GBG86939.1 - 1.3 8.9 16.0 0.94 9.4 10.7 2.8 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 CRR7 PF12095.8 GBG86939.1 - 2.4 8.6 5.6 3.4 8.2 1.3 2.5 1 1 1 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Csm1_N PF18504.1 GBG86939.1 - 2.6 8.4 10.3 0.29 11.5 0.9 2.8 2 1 0 2 2 2 0 Csm1 N-terminal domain DivIC PF04977.15 GBG86939.1 - 3.6 7.4 7.4 0.26 11.1 0.6 2.5 3 0 0 3 3 2 0 Septum formation initiator Laminin_II PF06009.12 GBG86939.1 - 3.7 7.6 6.3 1.4 8.9 3.4 1.8 2 0 0 2 2 2 0 Laminin Domain II zf-rbx1 PF12678.7 GBG86939.1 - 3.8 7.9 12.5 0.31 11.4 6.2 2.6 2 1 0 2 2 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 GBG86939.1 - 4.9 7.0 7.2 1 9.2 3.2 2.0 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain I_LWEQ PF01608.17 GBG86939.1 - 6 7.1 10.2 3.4 7.9 6.5 2.1 2 0 0 2 2 2 0 I/LWEQ domain MCU PF04678.13 GBG86939.1 - 6.6 6.8 7.0 31 4.6 7.0 2.0 1 1 0 1 1 1 0 Mitochondrial calcium uniporter HR1 PF02185.16 GBG86939.1 - 6.7 6.9 11.8 1e+02 3.1 11.8 2.4 1 1 0 1 1 1 0 Hr1 repeat DUF2205 PF10224.9 GBG86939.1 - 6.8 6.8 7.6 4.1 7.5 0.0 3.0 3 0 0 3 3 3 0 Short coiled-coil protein Syntaxin-6_N PF09177.11 GBG86939.1 - 7.6 7.2 6.8 1.4e+02 3.1 6.0 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CDC45 PF02724.14 GBG86940.1 - 3.8 5.7 26.5 3.8 5.7 26.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_6 PF12697.7 GBG86941.1 - 5.4e-21 76.2 0.5 5.4e-21 76.2 0.5 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG86941.1 - 5.9e-16 58.9 0.0 1.1e-12 48.2 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG86941.1 - 6e-11 42.1 0.0 1.3e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GBG86941.1 - 0.044 13.7 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase RVT_1 PF00078.27 GBG86942.1 - 7.3e-30 104.1 0.0 1.3e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG86943.1 - 7e-23 81.0 0.0 9.1e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG86943.1 - 8e-13 48.5 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein TPR_12 PF13424.6 GBG86944.1 - 8.9e-07 29.1 4.7 0.13 12.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG86944.1 - 7e-06 25.8 3.5 0.15 12.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2052 PF09747.9 GBG86944.1 - 2.1e-05 24.7 23.2 0.0055 16.9 8.5 3.7 3 0 0 3 3 3 2 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 GBG86944.1 - 0.0013 17.1 40.8 0.053 11.7 11.2 2.4 2 0 0 2 2 2 2 Nop14-like family RNase_H2_suC PF08615.11 GBG86944.1 - 0.0054 16.9 3.8 0.91 9.7 0.3 2.7 2 0 0 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SDA1 PF05285.12 GBG86944.1 - 0.042 13.3 35.9 0.034 13.6 10.7 2.8 3 0 0 3 3 2 0 SDA1 Utp14 PF04615.13 GBG86944.1 - 0.13 10.8 33.2 0.81 8.2 9.5 2.3 2 0 0 2 2 2 0 Utp14 protein TPR_1 PF00515.28 GBG86944.1 - 0.13 12.1 0.3 6.7 6.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SpoIIP PF07454.11 GBG86944.1 - 0.24 10.8 14.1 0.14 11.6 2.8 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SAPS PF04499.15 GBG86944.1 - 0.33 9.7 8.0 1.8 7.2 2.2 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein FAM176 PF14851.6 GBG86944.1 - 0.68 9.6 31.7 0.15 11.7 7.6 3.7 3 0 0 3 3 3 0 FAM176 family Connexin PF00029.19 GBG86944.1 - 0.78 9.5 10.1 2.2 8.0 3.7 2.5 2 0 0 2 2 2 0 Connexin RPN2_C PF18004.1 GBG86944.1 - 0.92 9.4 26.6 1.9 8.4 9.2 2.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Adaptin_binding PF10199.9 GBG86944.1 - 1 10.0 18.0 0.17 12.5 2.9 3.3 4 0 0 4 4 4 0 Alpha and gamma adaptin binding protein p34 DUF3391 PF11871.8 GBG86944.1 - 3 8.4 24.7 0.72 10.4 0.9 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3391) RAB3GAP2_C PF14656.6 GBG86944.1 - 9.5 4.3 9.9 2.6 6.1 3.9 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Slu7 PF11708.8 GBG86944.1 - 9.9 5.8 25.5 1.1 9.0 5.5 2.5 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Spt4 PF06093.13 GBG86945.1 - 2.5e-25 88.3 0.1 3.2e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger HIPIP PF01355.17 GBG86945.1 - 0.017 15.4 0.1 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 High potential iron-sulfur protein RVT_1 PF00078.27 GBG86946.1 - 1.1e-52 178.8 0.1 1.5e-26 93.3 0.1 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86946.1 - 2e-18 66.2 0.2 4.3e-18 65.2 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain BBIP10 PF14777.6 GBG86946.1 - 2.1e-18 65.7 0.7 1.4e-17 63.0 0.3 2.3 2 0 0 2 2 2 1 Cilia BBSome complex subunit 10 RT_RNaseH_2 PF17919.1 GBG86946.1 - 3.8e-15 55.7 0.0 7.9e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG86946.1 - 5.9e-15 55.5 0.1 1.9e-14 53.9 0.0 1.9 2 0 0 2 2 1 1 Integrase core domain RVP_2 PF08284.11 GBG86946.1 - 1.2e-06 28.3 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG86946.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86946.1 - 0.0061 17.2 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG86946.1 - 0.011 16.3 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG86946.1 - 0.082 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF5095 PF17016.5 GBG86946.1 - 0.31 10.7 1.4 6.8 6.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) Sporozoite_P67 PF05642.11 GBG86946.1 - 2 6.4 6.8 3.3 5.7 6.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Snf7 PF03357.21 GBG86947.1 - 3.3e-42 144.0 17.0 3.3e-42 144.0 17.0 2.0 2 0 0 2 2 2 1 Snf7 EMP24_GP25L PF01105.24 GBG86947.1 - 4.5 7.2 8.1 14 5.5 6.8 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Str_synth PF03088.16 GBG86948.1 - 1.3e-25 89.3 0.0 3.3e-25 88.0 0.0 1.7 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 GBG86948.1 - 3e-13 50.0 0.0 5.1e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GBG86948.1 - 0.0075 16.3 0.0 0.87 9.7 0.0 3.0 2 0 0 2 2 2 1 NHL repeat RT_RNaseH PF17917.1 GBG86949.1 - 3.1e-19 69.2 0.0 6.8e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86949.1 - 5.9e-17 61.5 0.0 1.4e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86949.1 - 1.6e-07 31.3 1.0 3.9e-07 30.1 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG86949.1 - 0.0075 16.5 0.1 0.027 14.8 0.1 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein EOS1 PF12326.8 GBG86949.1 - 0.18 11.7 0.4 0.41 10.5 0.4 1.6 1 0 0 1 1 1 0 N-glycosylation protein DDHD PF02862.17 GBG86949.1 - 0.18 11.9 2.7 0.43 10.7 2.7 1.7 1 1 0 1 1 1 0 DDHD domain CTNNB1_binding PF08347.11 GBG86949.1 - 6.5 6.9 6.3 1.6 8.9 1.7 2.1 2 0 0 2 2 2 0 N-terminal CTNNB1 binding CDC45 PF02724.14 GBG86949.1 - 7.1 4.8 14.4 0.13 10.5 7.1 1.7 2 0 0 2 2 2 0 CDC45-like protein RVT_1 PF00078.27 GBG86950.1 - 2.6e-27 95.8 0.0 4.5e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86950.1 - 1.7e-23 82.6 0.0 4.6e-23 81.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86950.1 - 1.4e-21 76.8 0.0 3.8e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86950.1 - 2.3e-19 69.2 0.6 7.5e-19 67.6 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86950.1 - 3.4e-10 40.1 0.0 1.2e-09 38.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG86951.1 - 5.4e-28 98.0 0.1 1e-27 97.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86951.1 - 2.7e-22 78.7 0.0 6.2e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86951.1 - 1.8e-21 76.4 0.0 3.6e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG86951.1 - 0.035 13.9 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG86952.1 - 7.9e-33 113.8 0.1 1.4e-32 113.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86952.1 - 2.1e-23 82.2 0.0 4.6e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86952.1 - 7.3e-22 77.6 0.0 2.2e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86952.1 - 1e-16 60.8 0.7 2.7e-16 59.4 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG86954.1 - 0.00057 20.1 0.3 0.00057 20.1 0.3 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG86954.1 - 0.0031 17.3 0.7 0.011 15.5 0.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Taxilin PF09728.9 GBG86955.1 - 0.0023 17.2 22.4 0.0028 16.9 22.4 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein PA26 PF04636.13 GBG86955.1 - 0.076 11.9 14.1 0.088 11.7 14.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Herpes_UL25 PF01499.16 GBG86955.1 - 0.25 9.8 11.2 0.28 9.6 11.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family TTKRSYEDQ PF10212.9 GBG86955.1 - 0.42 9.5 16.4 0.49 9.3 16.4 1.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein RSRP PF17069.5 GBG86955.1 - 1.7 8.1 9.0 2 7.9 9.0 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Paf1 PF03985.13 GBG86955.1 - 1.9 7.4 23.3 2.5 7.0 23.3 1.2 1 0 0 1 1 1 0 Paf1 FAM60A PF15396.6 GBG86955.1 - 5.5 6.9 11.9 6.5 6.7 11.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF5401 PF17380.2 GBG86955.1 - 5.9 4.8 24.1 7 4.6 24.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DDHD PF02862.17 GBG86955.1 - 7.8 6.6 10.0 8.9 6.4 10.0 1.1 1 0 0 1 1 1 0 DDHD domain DsrH PF04077.12 GBG86956.1 - 0.0014 18.8 71.3 55 4.0 0.1 28.4 28 7 10 39 39 39 3 DsrH like protein RNA_pol_Rpc34 PF05158.12 GBG86956.1 - 7.8 5.8 30.4 0.11 11.8 0.1 9.9 8 2 2 10 10 10 0 RNA polymerase Rpc34 subunit RT_RNaseH_2 PF17919.1 GBG86957.1 - 2e-19 69.4 0.0 4.1e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86957.1 - 5.7e-19 68.4 0.0 1.5e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86957.1 - 2e-12 47.0 0.0 6.3e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86957.1 - 4.2e-05 23.7 0.0 8.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG86957.1 - 0.024 14.9 0.4 0.14 12.5 0.2 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG86957.1 - 0.025 14.8 0.1 0.061 13.6 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC_2 PF13696.6 GBG86957.1 - 4.5 7.2 5.8 0.48 10.3 1.2 1.8 2 0 0 2 2 2 0 Zinc knuckle SlyX PF04102.12 GBG86958.1 - 0.084 13.5 1.1 1 10.0 0.0 2.5 2 0 0 2 2 2 0 SlyX DUF2785 PF10978.8 GBG86959.1 - 0.47 10.2 2.9 3.1 7.5 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) RVT_1 PF00078.27 GBG86960.1 - 4.2e-20 72.2 0.2 7e-20 71.5 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG86961.1 - 0.03 14.4 0.5 0.06 13.5 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG86961.1 - 0.067 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 GBG86962.1 - 2.3e-08 34.2 1.5 1.4e-07 31.7 0.1 2.8 3 0 0 3 3 3 1 Integrase core domain Retrotrans_gag PF03732.17 GBG86962.1 - 0.0032 17.7 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG86963.1 - 8e-16 57.9 0.0 2.4e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86963.1 - 5.5e-10 39.1 0.3 9.1e-10 38.4 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86963.1 - 0.00042 20.6 0.0 0.00098 19.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG86963.1 - 0.002 18.4 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein PRTP PF01366.18 GBG86964.1 - 2.2 6.2 10.8 3.3 5.7 10.8 1.3 1 1 0 1 1 1 0 Herpesvirus processing and transport protein Herpes_UL25 PF01499.16 GBG86964.1 - 9.7 4.6 14.5 2.3 6.6 10.5 1.7 2 0 0 2 2 2 0 Herpesvirus UL25 family RVT_1 PF00078.27 GBG86965.1 - 1.3e-27 96.8 0.1 2.1e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YabA PF06156.13 GBG86965.1 - 0.082 13.5 0.7 0.48 11.1 0.0 2.4 2 0 0 2 2 2 0 Initiation control protein YabA P4Ha_N PF08336.11 GBG86965.1 - 0.17 11.9 1.8 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region GCN5L1 PF06320.13 GBG86965.1 - 0.92 9.7 5.8 0.94 9.6 3.5 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Poty_PP PF08440.10 GBG86965.1 - 6.7 5.7 5.8 1.7 7.7 0.7 2.3 3 0 0 3 3 3 0 Potyviridae polyprotein RVT_1 PF00078.27 GBG86966.1 - 0.0004 20.0 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG86966.1 - 0.00065 20.2 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG86966.1 - 0.00088 19.9 0.0 0.0019 18.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG86966.1 - 0.0024 18.2 0.1 0.0073 16.6 0.1 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86966.1 - 0.0078 16.0 0.6 0.052 13.3 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG86966.1 - 0.05 13.9 0.2 0.13 12.5 0.2 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Strep_SA_rep PF06696.11 GBG86966.1 - 0.12 12.4 0.2 0.12 12.4 0.2 1.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat zf-CCHC_2 PF13696.6 GBG86966.1 - 9.3 6.2 6.3 1.7 8.5 2.4 1.8 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG86967.1 - 0.0079 16.5 0.4 0.014 15.6 0.4 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1840 PF08895.11 GBG86968.1 - 0.35 11.2 4.1 4.7 7.6 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) DUF4407 PF14362.6 GBG86968.1 - 7.9 5.7 12.9 8.8 5.6 11.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Pkinase_Tyr PF07714.17 GBG86969.1 - 2.3e-39 135.2 0.0 3.3e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86969.1 - 1.4e-38 132.8 0.0 2.3e-24 86.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG86969.1 - 0.028 14.3 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FixQ PF05545.11 GBG86969.1 - 0.091 12.7 1.7 0.21 11.6 1.7 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Pkinase PF00069.25 GBG86970.1 - 9.2e-37 126.8 0.0 3e-23 82.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG86970.1 - 2.8e-36 125.1 0.0 3.9e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG86970.1 - 0.00087 19.3 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG86970.1 - 0.071 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 GBG86972.1 - 1.1e-31 110.0 0.0 1.5e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86972.1 - 2.6e-30 105.7 0.0 8.6e-22 77.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 GBG86972.1 - 0.22 10.2 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 GBG86975.1 - 1.4e-39 136.0 0.0 2e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86975.1 - 4e-38 131.3 0.0 3.4e-24 85.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG86975.1 - 0.023 14.6 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RVT_1 PF00078.27 GBG86976.1 - 2.3e-28 99.3 0.0 3.6e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG86976.1 - 7.8e-12 45.1 0.1 3.2e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86976.1 - 4.4e-11 43.0 0.0 1.1e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Pkinase_Tyr PF07714.17 GBG86976.1 - 0.00035 20.0 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-H2C2 PF09337.10 GBG86976.1 - 0.015 15.5 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Pkinase_Tyr PF07714.17 GBG86977.1 - 1.7e-35 122.6 0.0 2.5e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG86977.1 - 2.2e-32 112.5 0.0 3.2e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG86977.1 - 0.00071 19.6 0.1 0.0025 17.8 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG86977.1 - 0.018 13.8 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RT_RNaseH PF17917.1 GBG86978.1 - 8.9e-21 74.2 0.0 2.1e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86978.1 - 1.9e-19 69.5 0.0 4.4e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86978.1 - 5.3e-14 52.1 0.1 1.7e-13 50.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG86978.1 - 1.7e-13 50.8 0.0 6.3e-13 49.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86978.1 - 7.7e-07 29.6 0.0 2.2e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG86978.1 - 2.5e-06 27.2 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG86978.1 - 0.00019 22.0 0.3 0.00089 19.9 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG86978.1 - 0.0033 17.6 0.0 0.013 15.8 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG86978.1 - 0.036 13.9 1.0 0.072 12.9 1.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG86978.1 - 0.053 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease FAM184 PF15665.5 GBG86979.1 - 5.3e-06 26.4 10.6 6.2e-06 26.2 10.6 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B DUF4618 PF15397.6 GBG86979.1 - 0.00066 19.2 4.5 0.0021 17.6 4.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) PhaP_Bmeg PF09602.10 GBG86979.1 - 0.0013 18.7 0.7 0.0015 18.5 0.7 1.1 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Apolipoprotein PF01442.18 GBG86979.1 - 0.0022 17.9 6.5 0.0034 17.3 6.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YaiA PF16362.5 GBG86979.1 - 0.003 17.6 0.4 0.28 11.3 0.1 2.6 1 1 1 2 2 2 2 YaiA protein AAA_13 PF13166.6 GBG86979.1 - 0.0033 16.2 6.1 0.0038 15.9 6.1 1.0 1 0 0 1 1 1 1 AAA domain ApoLp-III PF07464.11 GBG86979.1 - 0.0041 17.2 4.7 0.032 14.3 0.3 2.1 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Filament PF00038.21 GBG86979.1 - 0.029 13.9 10.6 0.034 13.7 10.6 1.0 1 0 0 1 1 1 0 Intermediate filament protein OmpH PF03938.14 GBG86979.1 - 0.036 14.4 5.6 0.047 14.0 5.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HIP1_clath_bdg PF16515.5 GBG86979.1 - 0.05 14.2 7.5 0.092 13.4 7.3 1.5 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PAS_12 PF18095.1 GBG86979.1 - 0.059 13.0 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain HAUS6_N PF14661.6 GBG86979.1 - 0.062 12.9 7.6 0.085 12.4 7.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Rho_Binding PF08912.11 GBG86979.1 - 0.68 10.8 9.0 5.7 7.8 0.9 2.5 2 1 0 2 2 2 0 Rho Binding DUF4407 PF14362.6 GBG86979.1 - 0.76 9.1 5.4 1.1 8.6 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 GBG86979.1 - 1.5 8.0 3.6 2 7.6 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Metal_resist PF13801.6 GBG86979.1 - 5.3 7.2 12.0 6.8 6.9 10.1 2.1 2 1 0 2 2 2 0 Heavy-metal resistance WD40 PF00400.32 GBG86980.1 - 2.4e-11 44.0 6.7 3.8e-06 27.5 0.2 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG86980.1 - 0.00056 20.1 0.0 0.081 13.2 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CLZ PF16526.5 GBG86980.1 - 0.23 11.9 5.3 0.6 10.5 4.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BST2 PF16716.5 GBG86980.1 - 0.3 11.7 3.1 0.53 10.9 3.1 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DnaJ_CXXCXGXG PF00684.19 GBG86981.1 - 0.0019 18.5 16.2 0.019 15.4 16.9 2.3 1 1 1 2 2 2 2 DnaJ central domain DUF5351 PF17302.2 GBG86981.1 - 0.13 12.5 0.8 0.13 12.5 0.8 3.5 2 1 1 3 3 3 0 Family of unknown function (DUF5351) DUF1356 PF07092.12 GBG86981.1 - 6.9 5.9 8.1 4.9 6.4 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) WD40 PF00400.32 GBG86982.1 - 2.1e-15 56.8 11.1 3.9e-05 24.3 0.4 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Frtz PF11768.8 GBG86982.1 - 0.00019 19.9 0.1 0.0004 18.8 0.1 1.4 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.7 GBG86982.1 - 0.029 14.6 0.3 1.6 9.1 0.2 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NAP PF00956.18 GBG86983.1 - 6.6e-72 241.9 2.5 1.3e-71 241.0 2.5 1.5 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) RhlB PF12300.8 GBG86983.1 - 0.015 15.4 0.2 0.015 15.4 0.2 1.9 3 0 0 3 3 3 0 ATP-dependent RNA helicase RhlB DUF4757 PF15949.5 GBG86983.1 - 0.018 15.5 0.3 0.048 14.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) Cwf_Cwc_15 PF04889.12 GBG86983.1 - 8.5 6.0 19.5 7.1 6.3 11.9 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF659 PF04937.15 GBG86984.1 - 1.3e-17 64.0 0.0 2.1e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG86984.1 - 2.7e-08 33.5 0.2 5.2e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SDA1 PF05285.12 GBG86984.1 - 2.9 7.2 41.7 3.9 6.8 25.5 2.5 2 0 0 2 2 2 0 SDA1 Ldl_recept_a PF00057.18 GBG86985.1 - 2.2e-26 91.8 125.6 1e-08 35.2 4.2 11.1 10 1 0 11 11 11 9 Low-density lipoprotein receptor domain class A zf-CCHC PF00098.23 GBG86985.1 - 0.00047 20.1 2.0 0.00047 20.1 2.0 3.2 2 0 0 2 2 2 1 Zinc knuckle RVT_1 PF00078.27 GBG86986.1 - 5.6e-29 101.2 0.1 1e-28 100.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG86986.1 - 2.6e-13 49.8 0.0 7.5e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG86986.1 - 0.14 12.5 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase NAP PF00956.18 GBG86987.1 - 1.8e-70 237.2 3.8 4.9e-70 235.8 3.8 1.7 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) RhlB PF12300.8 GBG86987.1 - 0.015 15.4 0.1 0.015 15.4 0.1 1.9 3 0 0 3 3 3 0 ATP-dependent RNA helicase RhlB DUF4757 PF15949.5 GBG86987.1 - 0.025 15.1 0.2 0.069 13.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) Ufm1 PF03671.14 GBG86988.1 - 3.5e-43 145.6 0.1 4e-43 145.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Med12 PF09497.10 GBG86989.1 - 3.1e-10 40.2 0.0 8.7e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 GBG86989.1 - 0.037 12.9 0.0 4.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic Mediator 12 subunit domain CTD_bind PF04818.13 GBG86990.1 - 7.8e-11 42.6 0.0 2e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Surp PF01805.20 GBG86990.1 - 9.9e-11 41.5 0.4 1.9e-10 40.5 0.4 1.4 1 0 0 1 1 1 1 Surp module Sporozoite_P67 PF05642.11 GBG86990.1 - 0.00066 17.9 10.6 0.038 12.1 4.7 3.2 2 2 1 3 3 3 2 Sporozoite P67 surface antigen TFIIA PF03153.13 GBG86990.1 - 0.0035 17.4 29.0 0.0035 17.4 29.0 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 GBG86990.1 - 0.094 11.7 30.8 0.038 13.0 18.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Neur_chan_memb PF02932.16 GBG86990.1 - 0.45 10.5 6.0 0.55 10.2 2.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 GBG86990.1 - 0.98 9.5 7.0 0.095 12.8 0.2 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Spore_YhcN_YlaJ PF09580.10 GBG86990.1 - 1.8 8.7 15.3 1.2 9.2 9.9 2.7 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Ribosomal_60s PF00428.19 GBG86990.1 - 8.8 7.0 6.0 1e+02 3.5 0.1 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 GBG86991.1 - 5.2 7.0 15.3 6.6 6.6 15.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH_2 PF17919.1 GBG86993.1 - 6.9e-27 93.4 0.0 1.7e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG86993.1 - 1.1e-24 87.2 0.1 1.7e-24 86.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG86993.1 - 6.8e-24 84.2 0.0 1.7e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG86993.1 - 0.00056 20.5 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG86993.1 - 0.0039 17.0 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG86993.1 - 0.0059 17.1 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG86993.1 - 0.0089 15.9 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG86993.1 - 0.0094 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Sin3_corepress PF08295.12 GBG86994.1 - 1.3 9.2 10.5 0.33 11.0 0.4 3.0 3 0 0 3 3 3 0 Sin3 family co-repressor Fib_alpha PF08702.10 GBG86994.1 - 5.4 7.2 16.0 0.06 13.5 2.1 3.2 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family zf-CCHC_4 PF14392.6 GBG86995.1 - 1.2 8.9 3.6 3.1 7.6 1.1 2.4 2 0 0 2 2 2 0 Zinc knuckle MCU PF04678.13 GBG86995.1 - 3.1 7.9 5.3 1.3 9.1 2.7 1.7 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF4192 PF13830.6 GBG86995.1 - 7.9 6.4 16.9 0.72 9.9 11.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Mito_carr PF00153.27 GBG86998.1 - 4.4e-70 231.7 0.6 8e-23 80.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Miff PF05644.11 GBG86998.1 - 0.0015 18.2 0.8 0.0024 17.5 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff Serine_protease PF18405.1 GBG86998.1 - 0.0031 16.7 0.5 1.6 7.8 0.0 3.2 3 0 0 3 3 3 1 Gammaproteobacterial serine protease ANAPC_CDC26 PF10471.9 GBG86998.1 - 0.19 12.6 6.1 0.33 11.8 6.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 AF-4 PF05110.13 GBG86998.1 - 0.19 9.7 7.7 0.26 9.3 7.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GREB1 PF15782.5 GBG86998.1 - 0.25 8.4 3.4 0.33 8.0 3.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rrn6 PF10214.9 GBG86998.1 - 0.27 9.7 9.9 0.37 9.2 9.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF1168 PF06658.12 GBG86998.1 - 0.54 10.1 12.4 0.41 10.5 10.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) SR-25 PF10500.9 GBG86998.1 - 0.56 9.8 15.6 0.17 11.5 12.4 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 GBG86998.1 - 0.67 8.7 3.6 0.91 8.3 3.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF755 PF05501.11 GBG86998.1 - 1.3 9.4 15.3 2.1 8.6 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MAGE_N PF12440.8 GBG86998.1 - 1.4 9.6 17.2 0.1 13.3 9.6 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Rtf2 PF04641.12 GBG86998.1 - 2.6 7.4 6.0 3.8 6.8 6.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RT_RNaseH PF17917.1 GBG86999.1 - 2.9e-22 79.0 0.0 2.6e-21 75.9 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG86999.1 - 4e-20 71.7 0.0 7.4e-19 67.6 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG86999.1 - 3.2e-11 43.2 0.5 7.3e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG86999.1 - 2.2e-10 40.8 0.0 7.4e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG86999.1 - 2.3e-10 40.9 0.0 5.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG86999.1 - 4.6e-07 29.6 0.0 9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG86999.1 - 5.8e-07 30.1 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG86999.1 - 5e-05 23.6 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG86999.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease UBX PF00789.20 GBG87000.1 - 2.3e-09 37.3 0.0 4.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBX PF00789.20 GBG87001.1 - 2.1e-09 37.5 0.0 4.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBX PF00789.20 GBG87002.1 - 1.7e-09 37.8 0.0 3.4e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain Borrelia_P83 PF05262.11 GBG87002.1 - 0.014 13.9 7.4 0.016 13.7 7.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1977 PF09320.11 GBG87002.1 - 0.22 11.8 7.0 0.4 10.9 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) RVT_1 PF00078.27 GBG87003.1 - 4.2e-24 85.3 0.1 8e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG87003.1 - 4.8e-07 30.3 0.0 1.3e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87003.1 - 2.8e-06 27.8 0.0 6.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87003.1 - 0.00014 21.6 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87003.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG87003.1 - 0.018 15.3 2.8 0.053 13.8 2.0 2.2 1 1 0 1 1 1 0 Retrotransposon gag protein DUF3491 PF11996.8 GBG87003.1 - 0.061 11.1 0.2 0.091 10.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) PK PF00224.21 GBG87004.1 - 9.9e-47 159.5 0.1 1.2e-35 123.0 0.1 2.2 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain CENP-K PF11802.8 GBG87005.1 - 0.57 9.7 5.8 0.51 9.9 4.3 1.4 1 1 0 1 1 1 0 Centromere-associated protein K CREPT PF16566.5 GBG87005.1 - 7.9 6.7 10.4 11 6.1 4.7 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour RVT_1 PF00078.27 GBG87006.1 - 4.3e-24 85.3 0.0 6.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG87006.1 - 7e-08 33.1 5.4 2.4e-07 31.4 5.4 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF2757 PF10955.8 GBG87006.1 - 0.024 14.9 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) Dimer_Tnp_hAT PF05699.14 GBG87007.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF773 PF05600.12 GBG87007.1 - 0.08 11.7 1.5 0.11 11.2 1.5 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 RVT_1 PF00078.27 GBG87008.1 - 8.2e-35 120.3 0.1 1.6e-34 119.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87008.1 - 0.00016 21.4 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87008.1 - 0.002 18.8 0.0 0.0049 17.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87008.1 - 0.024 15.2 0.0 0.053 14.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87008.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG87009.1 - 2.1e-28 99.4 0.0 3.2e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87009.1 - 2.4e-21 75.6 0.0 5.2e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87009.1 - 9.1e-09 35.6 0.0 1.9e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ANAPC4_WD40 PF12894.7 GBG87009.1 - 0.041 14.2 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 GBG87010.1 - 7.8e-37 126.9 0.1 1.4e-36 126.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87010.1 - 4.7e-29 100.8 0.0 1.2e-28 99.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87010.1 - 1.3e-28 98.9 0.0 3.6e-28 97.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87010.1 - 6.8e-18 64.5 2.1 1.8e-17 63.2 2.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG87010.1 - 0.034 14.4 0.1 0.14 12.4 0.1 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG87010.1 - 0.034 13.8 0.0 0.034 13.8 0.0 3.0 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Arc_PepC_II PF06847.11 GBG87010.1 - 0.48 11.0 4.1 36 4.9 0.0 3.5 3 1 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II RVT_1 PF00078.27 GBG87011.1 - 2.2e-30 105.9 0.1 4.7e-30 104.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87011.1 - 1.6e-20 73.0 0.2 2.3e-13 50.0 0.0 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87011.1 - 3.4e-19 69.1 1.5 1.3e-13 51.1 1.1 2.9 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87011.1 - 1.5e-15 57.0 0.1 3.2e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87011.1 - 3.6e-11 43.3 0.0 1.6e-10 41.2 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG87011.1 - 0.037 14.3 0.3 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG87011.1 - 0.096 12.9 0.0 0.37 11.1 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger FAM199X PF15814.5 GBG87011.1 - 1.8 7.6 7.5 2.9 6.9 7.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X RVT_1 PF00078.27 GBG87012.1 - 2.2e-30 105.8 0.1 3.6e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87012.1 - 1.3e-20 73.3 0.2 1.9e-13 50.3 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87012.1 - 2.5e-19 69.5 1.5 1.1e-13 51.4 1.1 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87012.1 - 1.2e-15 57.3 0.1 2.6e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87012.1 - 3.1e-11 43.5 0.0 1.3e-10 41.5 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG87012.1 - 0.071 13.3 0.0 0.3 11.3 0.0 2.2 1 0 0 1 1 1 0 H2C2 zinc finger FAM199X PF15814.5 GBG87012.1 - 1.4 7.9 7.5 2.3 7.2 7.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X RVT_1 PF00078.27 GBG87013.1 - 2.4e-26 92.6 0.0 3.6e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAZ PF02170.22 GBG87013.1 - 4.6e-17 62.1 0.2 9.6e-17 61.1 0.2 1.6 1 0 0 1 1 1 1 PAZ domain DUF1764 PF08576.10 GBG87013.1 - 0.18 12.7 7.5 0.51 11.3 7.5 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DDRGK PF09756.9 GBG87013.1 - 1.3 8.5 19.0 2.1 7.9 19.0 1.2 1 0 0 1 1 1 0 DDRGK domain rve PF00665.26 GBG87014.1 - 2.2e-09 37.5 0.0 4.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG87014.1 - 9.5e-05 22.2 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG87014.1 - 0.0056 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.14 GBG87015.1 - 1.1e-09 38.0 0.2 3.3e-08 33.2 0.1 2.4 2 0 0 2 2 2 2 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG87016.1 - 2.6e-20 72.3 0.0 6.2e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87016.1 - 1e-16 60.8 0.3 4.5e-16 58.7 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG87016.1 - 5.3e-12 46.0 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87016.1 - 1.5e-09 37.7 0.1 2.5e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG87016.1 - 1.8e-08 34.6 0.2 5.8e-08 33.0 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG87016.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG87017.1 - 0.019 15.2 8.2 0.19 12.1 0.0 4.4 4 2 1 5 5 5 0 Retrotransposon gag protein DUF2781 PF10914.8 GBG87017.1 - 0.15 12.4 0.1 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Sulfatase_C PF14707.6 GBG87017.1 - 1.3 9.8 4.6 0.56 11.0 0.5 2.3 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DUF4288 PF14119.6 GBG87017.1 - 3.9 7.9 5.5 10 6.6 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4288) DUF1664 PF07889.12 GBG87017.1 - 7.5 6.6 5.8 43 4.2 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) TetR_C_28 PF17937.1 GBG87017.1 - 9.8 6.7 14.3 3.1 8.3 0.1 3.9 3 2 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Piwi PF02171.17 GBG87018.1 - 2.2e-52 178.2 0.0 3.8e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 Piwi domain Retrotrans_gag PF03732.17 GBG87018.1 - 0.012 15.9 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein PNMA PF14893.6 GBG87018.1 - 0.096 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 PNMA gpUL132 PF11359.8 GBG87018.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 Iwr1 PF08574.10 GBG87020.1 - 0.84 10.7 16.3 0.73 10.9 9.3 2.8 2 0 0 2 2 2 0 Transcription factor Iwr1 ATP_bind_1 PF03029.17 GBG87021.1 - 1.1e-76 257.8 0.0 1.4e-76 257.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 GBG87021.1 - 9.4e-08 31.8 0.0 5.4e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GBG87021.1 - 6.2e-05 23.0 0.0 0.0005 20.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GBG87021.1 - 8.1e-05 23.1 0.0 0.00022 21.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 GBG87021.1 - 0.00018 21.3 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 GBG87021.1 - 0.00018 21.2 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 GBG87021.1 - 0.00022 21.4 0.0 0.00089 19.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 GBG87021.1 - 0.00028 20.5 0.1 0.077 12.6 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 GBG87021.1 - 0.00039 19.7 0.0 0.00065 19.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain FeoB_N PF02421.18 GBG87021.1 - 0.00044 19.8 0.1 0.025 14.1 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B Zeta_toxin PF06414.12 GBG87021.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 GBG87021.1 - 0.0019 17.3 0.0 0.017 14.1 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 GBG87021.1 - 0.002 18.0 0.0 1.9 8.3 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase NACHT PF05729.12 GBG87021.1 - 0.002 18.0 0.1 0.0035 17.3 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GBG87021.1 - 0.0025 18.1 0.0 0.019 15.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 GBG87021.1 - 0.0027 17.4 0.4 0.045 13.5 0.1 2.5 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 GBG87021.1 - 0.0028 17.4 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 GBG87021.1 - 0.005 16.8 0.0 0.74 9.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG87021.1 - 0.0086 16.4 0.1 0.055 13.8 0.1 1.9 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 GBG87021.1 - 0.013 14.7 0.0 0.061 12.5 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit CbiA PF01656.23 GBG87021.1 - 0.015 15.4 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.16 GBG87021.1 - 0.022 14.2 0.0 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein SRPRB PF09439.10 GBG87021.1 - 0.023 14.1 0.0 0.49 9.8 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DLIC PF05783.11 GBG87021.1 - 0.026 13.4 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) NTPase_1 PF03266.15 GBG87021.1 - 0.036 14.0 0.0 0.63 9.9 0.0 2.1 2 0 0 2 2 2 0 NTPase Ras PF00071.22 GBG87021.1 - 0.047 13.3 0.1 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Ras family AAA_18 PF13238.6 GBG87021.1 - 0.048 14.2 0.0 0.11 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 GBG87021.1 - 0.049 13.5 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 GBG87021.1 - 0.049 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase MipZ PF09140.11 GBG87021.1 - 0.05 12.9 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ AAA_5 PF07728.14 GBG87021.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 GBG87021.1 - 0.074 12.9 0.3 0.16 11.8 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.21 GBG87021.1 - 0.084 12.2 0.0 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GBG87021.1 - 0.084 12.9 0.1 0.42 10.6 0.1 2.0 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GBG87021.1 - 0.085 12.9 0.0 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Arf PF00025.21 GBG87021.1 - 0.087 12.3 0.0 0.31 10.5 0.0 1.8 3 0 0 3 3 2 0 ADP-ribosylation factor family ABC_tran PF00005.27 GBG87021.1 - 0.091 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 GBG87021.1 - 0.094 12.5 0.5 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain 6PF2K PF01591.18 GBG87021.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_7 PF12775.7 GBG87021.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 GBG87021.1 - 0.2 11.4 0.0 0.5 10.1 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 GBG87021.1 - 0.26 10.5 0.0 0.46 9.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CDC45 PF02724.14 GBG87022.1 - 1.5 7.0 16.8 2.8 6.1 16.8 1.4 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GBG87022.1 - 4 5.9 10.8 5.8 5.3 10.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3824 PF12868.7 GBG87023.1 - 0.082 13.6 4.1 0.22 12.2 4.1 1.7 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Cupin_1 PF00190.22 GBG87025.1 - 1.6e-29 102.5 2.3 3.9e-20 72.0 1.2 3.6 2 1 0 2 2 2 2 Cupin Cupin_6 PF12852.7 GBG87025.1 - 0.0096 15.7 0.0 5.3 6.7 0.0 2.6 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.12 GBG87025.1 - 0.011 15.4 0.0 6 6.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 GBG87026.1 - 9.9e-29 99.9 0.5 9.9e-21 73.9 0.8 2.8 2 1 0 2 2 2 2 Cupin Cupin_3 PF05899.12 GBG87026.1 - 0.011 15.4 0.0 6 6.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 GBG87027.1 - 9.8e-39 132.4 0.4 9e-22 77.3 0.7 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.12 GBG87027.1 - 6.4e-05 22.6 0.2 0.5 10.1 0.0 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF861) Cupin_6 PF12852.7 GBG87027.1 - 0.00073 19.3 0.1 0.76 9.5 0.0 2.4 2 0 0 2 2 2 2 Cupin ARD PF03079.14 GBG87027.1 - 0.039 14.1 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 ARD/ARD' family DUF659 PF04937.15 GBG87028.1 - 6.8e-19 68.2 0.0 9.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG87029.1 - 2.6e-33 115.0 0.3 2.6e-33 115.0 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87029.1 - 5.9e-07 29.2 0.1 1.3e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FtsZ_C PF12327.8 GBG87030.1 - 9.1e-24 83.6 1.6 2.3e-23 82.3 1.6 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin PF00091.25 GBG87030.1 - 1.1e-18 68.1 1.1 2.2e-18 67.2 1.1 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain TMEM100 PF16311.5 GBG87030.1 - 0.094 12.3 0.2 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 NAD_binding_10 PF13460.6 GBG87030.1 - 0.92 9.4 5.9 0.7 9.8 0.1 3.1 3 1 0 3 3 3 0 NAD(P)H-binding IPK PF03770.16 GBG87031.1 - 1.5e-36 126.1 0.0 2.3e-36 125.5 0.0 1.3 1 1 0 1 1 1 1 Inositol polyphosphate kinase RT_RNaseH_2 PF17919.1 GBG87032.1 - 2.3e-33 114.2 0.0 4.6e-33 113.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87032.1 - 4.8e-29 100.7 0.0 1.3e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87032.1 - 1.5e-17 63.8 0.0 3.1e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG87032.1 - 2.3e-14 53.6 0.1 1.1e-13 51.5 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain Cyclin_N PF00134.23 GBG87034.1 - 7.4e-24 83.9 0.1 1.5e-19 70.0 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GBG87034.1 - 0.00015 21.9 0.1 0.00069 19.7 0.0 2.0 2 1 0 2 2 2 1 Cyclin, C-terminal domain Mito_fiss_reg PF05308.11 GBG87034.1 - 0.16 12.1 10.6 0.51 10.4 10.6 1.9 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF659 PF04937.15 GBG87036.1 - 6.7e-17 61.7 0.0 1.3e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-FCS PF06467.14 GBG87036.1 - 0.062 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HTH_Tnp_Tc5 PF03221.16 GBG87036.1 - 0.12 12.4 1.0 0.34 11.0 0.4 2.1 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain tify PF06200.14 GBG87036.1 - 0.14 11.5 0.4 1.2 8.5 0.1 2.4 2 0 0 2 2 2 0 tify domain DUF4852 PF16144.5 GBG87037.1 - 0.044 13.9 1.0 0.22 11.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4852) DUF4373 PF14297.6 GBG87037.1 - 0.093 13.5 0.6 0.27 12.0 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) DUF1043 PF06295.12 GBG87037.1 - 0.12 12.4 2.1 5 7.2 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Retrotrans_gag PF03732.17 GBG87037.1 - 0.12 12.7 3.7 0.16 12.2 0.9 2.5 1 1 1 2 2 2 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG87037.1 - 0.78 9.6 3.2 1.5 8.7 3.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 GBG87037.1 - 3.2 6.4 6.1 4.3 6.0 6.1 1.1 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG87038.1 - 1.5e-08 34.4 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG87038.1 - 0.0066 16.7 0.3 0.28 11.5 0.0 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein Tyrosinase PF00264.20 GBG87041.1 - 2.9e-30 106.2 9.9 1.9e-16 61.0 1.1 2.2 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG87041.1 - 2.7e-15 55.9 1.0 5.7e-15 54.8 1.0 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain PPO1_KFDV PF12143.8 GBG87041.1 - 0.00054 20.1 0.0 0.00087 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF_B2219) Tyrosinase PF00264.20 GBG87042.1 - 4.6e-30 105.6 10.5 8e-16 59.0 2.2 2.4 1 1 1 2 2 2 2 Common central domain of tyrosinase PPO1_DWL PF12142.8 GBG87042.1 - 7.3e-14 51.3 0.4 1.5e-13 50.3 0.4 1.6 1 0 0 1 1 1 1 Polyphenol oxidase middle domain DUF89 PF01937.19 GBG87042.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF89 Oleosin PF01277.17 GBG87043.1 - 4.3e-07 29.7 17.9 1.4e-05 24.8 17.9 2.2 1 1 0 1 1 1 1 Oleosin gag-asp_proteas PF13975.6 GBG87044.1 - 2.2e-08 34.6 0.1 5.4e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87044.1 - 9.6e-06 26.2 0.1 2.6e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87044.1 - 6.8e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87044.1 - 0.00012 21.8 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease CENP_C_N PF15622.6 GBG87044.1 - 0.035 13.5 0.4 0.05 13.0 0.4 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal Peptidase_A3 PF02160.15 GBG87044.1 - 0.054 13.0 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) Tyrosinase PF00264.20 GBG87045.1 - 2e-28 100.2 16.9 6.8e-16 59.2 1.3 3.3 2 2 1 3 3 3 2 Common central domain of tyrosinase Integrase_H2C2 PF17921.1 GBG87045.1 - 1.5e-15 57.1 0.3 3.4e-15 55.9 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain PPO1_DWL PF12142.8 GBG87045.1 - 3e-14 52.5 1.2 6.4e-14 51.5 1.2 1.5 1 0 0 1 1 1 1 Polyphenol oxidase middle domain RVT_1 PF00078.27 GBG87045.1 - 1.9e-08 34.1 0.0 3.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG87045.1 - 6.1e-08 32.9 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain PPO1_KFDV PF12143.8 GBG87045.1 - 0.0018 18.4 0.0 0.0054 16.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF_B2219) zf-H2C2 PF09337.10 GBG87045.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Exonuc_VII_L PF02601.15 GBG87045.1 - 6.7 6.2 9.0 12 5.4 9.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF775 PF05603.12 GBG87046.1 - 0.0057 16.2 1.1 0.0058 16.2 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) FAM83 PF07894.12 GBG87046.1 - 0.13 11.7 0.5 0.14 11.6 0.5 1.0 1 0 0 1 1 1 0 FAM83 A-H Apolipoprotein PF01442.18 GBG87047.1 - 0.00058 19.8 11.9 0.0017 18.3 11.9 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mitofilin PF09731.9 GBG87047.1 - 0.011 14.6 10.7 0.012 14.5 10.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2130 PF09903.9 GBG87047.1 - 0.017 14.4 4.7 0.018 14.3 4.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF883 PF05957.13 GBG87047.1 - 0.097 13.3 10.9 1.5 9.5 6.5 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YbjQ_1 PF01906.17 GBG87047.1 - 0.15 12.7 4.2 0.14 12.8 2.7 1.6 1 1 0 1 1 1 0 Putative heavy-metal-binding Ax_dynein_light PF10211.9 GBG87047.1 - 0.3 11.0 7.0 0.34 10.8 7.0 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain YtxH PF12732.7 GBG87047.1 - 0.37 11.4 14.3 0.53 10.8 2.5 2.4 1 1 1 2 2 2 0 YtxH-like protein Roughex PF06020.11 GBG87047.1 - 1.2 8.2 7.7 1.3 8.0 7.7 1.0 1 0 0 1 1 1 0 Drosophila roughex protein LEA_4 PF02987.16 GBG87047.1 - 5.7 7.1 17.3 0.79 9.8 4.6 3.2 1 1 2 3 3 3 0 Late embryogenesis abundant protein LEA_4 PF02987.16 GBG87048.1 - 2.1e-12 46.9 101.6 2.5e-05 24.3 13.3 8.5 2 2 4 8 8 8 7 Late embryogenesis abundant protein Apolipoprotein PF01442.18 GBG87048.1 - 1.4e-06 28.4 80.5 3e-05 24.0 33.0 2.9 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GBG87048.1 - 4.9e-06 27.0 79.1 0.023 15.2 11.0 6.7 1 1 3 4 4 4 1 YtxH-like protein DUF883 PF05957.13 GBG87048.1 - 0.0095 16.5 80.4 0.47 11.1 8.7 6.1 2 2 5 7 7 7 7 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 GBG87049.1 - 0.00032 20.6 28.3 0.057 13.3 4.1 2.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Mitofilin PF09731.9 GBG87049.1 - 0.026 13.4 21.9 0.033 13.0 21.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YtxH PF12732.7 GBG87049.1 - 0.032 14.8 31.7 0.28 11.7 7.3 3.4 2 1 2 4 4 4 0 YtxH-like protein DUF883 PF05957.13 GBG87049.1 - 0.037 14.6 28.1 0.85 10.3 11.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Grg1 PF11034.8 GBG87049.1 - 0.44 10.8 24.5 2.8 8.2 2.9 3.5 1 1 2 3 3 3 0 Glucose-repressible protein Grg1 YbjQ_1 PF01906.17 GBG87049.1 - 1.6 9.4 6.3 2.1 9.0 5.1 1.8 1 1 0 1 1 1 0 Putative heavy-metal-binding DUF966 PF06136.13 GBG87049.1 - 2.5 7.8 12.7 3.1 7.4 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Phe_tRNA-synt_N PF02912.18 GBG87049.1 - 3.3 7.7 23.6 0.38 10.7 4.0 3.1 1 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Phasin PF05597.11 GBG87049.1 - 5.6 7.0 20.7 6 6.9 7.9 2.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SipA_VBS PF17985.1 GBG87049.1 - 9.1 6.4 5.9 6 7.0 0.3 2.7 3 0 0 3 3 3 0 SipA vinculin binding site Retrotrans_gag PF03732.17 GBG87050.1 - 0.001 19.3 0.1 0.0033 17.7 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG87050.1 - 0.006 16.3 0.6 0.029 14.2 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) RVT_1 PF00078.27 GBG87051.1 - 2.8e-28 98.9 0.0 4.7e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG87051.1 - 1.9e-07 31.6 0.0 5.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87051.1 - 4.1e-07 29.8 0.0 8.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG87051.1 - 1.8e-05 25.2 0.0 5.5e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease FAM76 PF16046.5 GBG87051.1 - 0.05 12.9 7.5 0.1 12.0 7.5 1.4 1 0 0 1 1 1 0 FAM76 protein YrbL-PhoP_reg PF10707.9 GBG87051.1 - 0.14 11.7 0.8 0.34 10.4 0.8 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PspB PF06667.12 GBG87051.1 - 4.5 7.4 10.9 12 6.1 3.0 3.3 3 0 0 3 3 3 0 Phage shock protein B Fasciclin PF02469.22 GBG87052.1 - 1e-05 25.8 0.0 1.5e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Pkinase_Tyr PF07714.17 GBG87053.1 - 9.3e-38 130.0 0.0 3e-37 128.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87053.1 - 2.7e-36 125.3 0.0 4.2e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LysM PF01476.20 GBG87053.1 - 4.1e-12 46.0 0.0 2.4e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 LysM domain APH PF01636.23 GBG87053.1 - 0.0014 18.7 2.0 0.16 11.8 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family PIP49_C PF12260.8 GBG87053.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase_Tyr PF07714.17 GBG87054.1 - 3.8e-38 131.3 0.0 2.4e-37 128.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87054.1 - 1.5e-36 126.1 0.0 2.2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LysM PF01476.20 GBG87054.1 - 1e-11 44.7 0.0 4.2e-06 26.7 0.1 2.6 2 0 0 2 2 2 2 LysM domain APH PF01636.23 GBG87054.1 - 0.023 14.6 1.6 1.3 8.9 0.3 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family MAP17 PF15807.5 GBG87054.1 - 0.059 13.6 0.3 0.12 12.6 0.3 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Apolipoprotein PF01442.18 GBG87055.1 - 0.007 16.3 7.6 0.0091 15.9 7.6 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mitofilin PF09731.9 GBG87055.1 - 0.022 13.6 7.3 0.025 13.5 7.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF883 PF05957.13 GBG87055.1 - 0.12 13.0 8.8 0.75 10.4 6.1 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) LEA_1 PF03760.15 GBG87055.1 - 0.46 11.2 23.7 1.3 9.7 18.0 2.3 2 1 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 Ax_dynein_light PF10211.9 GBG87055.1 - 0.58 10.1 7.9 0.62 10.0 7.9 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain YtxH PF12732.7 GBG87055.1 - 0.96 10.0 11.9 1e+02 3.5 11.9 2.3 1 1 0 1 1 1 0 YtxH-like protein DUF3584 PF12128.8 GBG87055.1 - 1.1 6.7 7.7 1.2 6.5 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Roughex PF06020.11 GBG87055.1 - 5.3 6.0 6.1 5.5 6.0 6.1 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Apolipoprotein PF01442.18 GBG87056.1 - 9.6e-05 22.3 11.4 0.00015 21.7 11.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GBG87056.1 - 0.039 14.6 12.8 0.42 11.3 6.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mitofilin PF09731.9 GBG87056.1 - 0.05 12.5 11.9 0.054 12.3 11.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YtxH PF12732.7 GBG87056.1 - 0.47 11.0 15.3 75 4.0 12.5 2.4 1 1 0 1 1 1 0 YtxH-like protein rRNA_processing PF08524.11 GBG87056.1 - 1.4 9.0 14.8 1.8 8.6 14.8 1.1 1 0 0 1 1 1 0 rRNA processing Ax_dynein_light PF10211.9 GBG87056.1 - 2.5 8.0 9.8 2.8 7.8 9.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF3584 PF12128.8 GBG87056.1 - 2.8 5.3 10.5 3.2 5.2 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LEA_1 PF03760.15 GBG87056.1 - 3.5 8.4 28.3 9.5 6.9 22.4 2.5 2 2 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 HisKA_3 PF07730.13 GBG87056.1 - 8.1 7.0 8.7 23 5.6 2.8 2.6 1 1 2 3 3 3 0 Histidine kinase Retrotrans_gag PF03732.17 GBG87057.1 - 0.0059 16.9 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Apolipoprotein PF01442.18 GBG87058.1 - 0.00037 20.4 9.1 0.0006 19.7 9.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mitofilin PF09731.9 GBG87058.1 - 0.014 14.2 9.3 0.017 14.0 9.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF883 PF05957.13 GBG87058.1 - 0.03 14.9 10.5 0.27 11.8 5.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GBG87058.1 - 0.5 10.9 14.3 1.1 9.8 4.2 2.4 1 1 1 2 2 2 0 YtxH-like protein LEA_1 PF03760.15 GBG87058.1 - 1.1 10.0 25.5 2.6 8.8 19.7 2.4 2 1 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 Ax_dynein_light PF10211.9 GBG87058.1 - 1.5 8.8 9.0 1.6 8.6 9.0 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF3584 PF12128.8 GBG87058.1 - 1.7 6.0 8.4 1.9 5.9 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HisKA_3 PF07730.13 GBG87058.1 - 2.9 8.5 7.1 8.9 6.9 2.0 2.5 1 1 2 3 3 3 0 Histidine kinase Apolipoprotein PF01442.18 GBG87059.1 - 0.00017 21.5 9.8 0.00028 20.8 9.8 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GBG87059.1 - 0.015 15.8 11.4 0.17 12.5 6.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mitofilin PF09731.9 GBG87059.1 - 0.018 13.9 10.1 0.02 13.8 10.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YtxH PF12732.7 GBG87059.1 - 0.035 14.6 12.8 0.67 10.5 2.6 2.3 1 1 1 2 2 2 0 YtxH-like protein Mis14 PF08641.12 GBG87059.1 - 0.12 12.7 5.4 0.17 12.2 5.4 1.2 1 0 0 1 1 1 0 Kinetochore protein Mis14 like UPF0767 PF15990.5 GBG87059.1 - 0.19 11.9 0.4 0.26 11.4 0.4 1.2 1 0 0 1 1 1 0 UPF0767 family Ax_dynein_light PF10211.9 GBG87059.1 - 1.4 8.8 7.4 1.5 8.7 7.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF3584 PF12128.8 GBG87059.1 - 1.6 6.1 8.8 1.8 6.0 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ISG65-75 PF11727.8 GBG87059.1 - 2 7.6 12.9 2.5 7.3 12.9 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein HisKA_3 PF07730.13 GBG87059.1 - 4.1 8.0 7.9 7.1 7.2 3.8 2.6 1 1 2 3 3 3 0 Histidine kinase ATP-synt_B PF00430.18 GBG87059.1 - 6.9 6.8 20.3 15 5.6 20.3 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) LEA_1 PF03760.15 GBG87059.1 - 7 7.4 26.4 22 5.8 20.5 2.5 2 2 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 MAJIN PF15077.6 GBG87059.1 - 9.3 6.0 7.0 10 5.8 7.0 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Apolipoprotein PF01442.18 GBG87060.1 - 0.00094 19.1 9.9 0.0014 18.5 9.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mitofilin PF09731.9 GBG87060.1 - 0.027 13.3 10.7 0.029 13.2 10.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF883 PF05957.13 GBG87060.1 - 0.042 14.5 10.5 0.59 10.8 6.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GBG87060.1 - 0.086 13.4 11.5 58 4.3 11.5 2.3 1 1 0 1 1 1 0 YtxH-like protein rRNA_processing PF08524.11 GBG87060.1 - 1 9.3 13.0 1.4 9.0 13.0 1.1 1 0 0 1 1 1 0 rRNA processing DUF3584 PF12128.8 GBG87060.1 - 1.3 6.4 8.2 1.4 6.4 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Presenilin PF01080.17 GBG87060.1 - 3.8 6.2 5.9 3.8 6.2 5.9 1.0 1 0 0 1 1 1 0 Presenilin LEA_1 PF03760.15 GBG87060.1 - 6.4 7.5 26.1 7.1 7.4 19.1 2.5 2 1 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 HisKA_3 PF07730.13 GBG87060.1 - 8.6 7.0 7.3 99 3.6 7.3 2.3 1 1 0 1 1 1 0 Histidine kinase Apolipoprotein PF01442.18 GBG87062.1 - 0.0018 18.1 19.4 0.12 12.3 13.0 2.0 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GBG87062.1 - 0.024 15.2 18.6 0.73 10.5 7.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GBG87062.1 - 0.061 13.9 23.1 0.96 10.0 4.8 3.3 1 1 2 3 3 3 0 YtxH-like protein Mitofilin PF09731.9 GBG87062.1 - 0.28 10.0 21.0 0.32 9.8 21.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein rRNA_processing PF08524.11 GBG87062.1 - 0.63 10.1 22.6 0.85 9.6 22.6 1.2 1 0 0 1 1 1 0 rRNA processing His_Phos_1 PF00300.22 GBG87062.1 - 0.67 9.6 7.0 0.94 9.1 7.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) BshC PF10079.9 GBG87062.1 - 1.3 7.7 9.2 1.4 7.5 9.2 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DHR10 PF18595.1 GBG87062.1 - 1.6 8.8 31.8 0.33 11.0 9.1 3.5 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain MAJIN PF15077.6 GBG87062.1 - 3 7.6 10.8 3.4 7.4 10.8 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF3584 PF12128.8 GBG87062.1 - 4.9 4.5 17.3 5.2 4.5 17.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 GBG87062.1 - 5.4 7.1 12.9 6.8 6.7 12.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 GBG87062.1 - 8 5.4 8.9 9.4 5.2 8.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Podoplanin PF05808.11 GBG87062.1 - 8.9 6.4 8.2 11 6.1 8.2 1.1 1 0 0 1 1 1 0 Podoplanin BAF1_ABF1 PF04684.13 GBG87062.1 - 9.1 5.2 13.5 10 5.0 13.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4407 PF14362.6 GBG87063.1 - 3.7 6.8 9.3 4.3 6.6 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cas_CT1975 PF09344.10 GBG87063.1 - 5.2 6.4 14.8 8 5.8 14.8 1.2 1 0 0 1 1 1 0 CT1975-like protein Nop14 PF04147.12 GBG87065.1 - 0.14 10.3 7.0 0.13 10.4 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG87065.1 - 0.29 10.5 8.0 0.31 10.4 8.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG87065.1 - 0.29 9.4 9.7 0.3 9.3 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG87065.1 - 2.5 6.1 14.0 3.2 5.7 14.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GBG87065.1 - 6.8 5.1 4.3 7 5.1 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 GBG87065.1 - 8 5.5 11.1 12 5.0 11.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RVT_1 PF00078.27 GBG87066.1 - 3.2e-19 69.3 0.0 6.1e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG87066.1 - 1.4e-12 47.3 0.0 3.8e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG87066.1 - 3.6e-07 30.4 0.0 1e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Myb_DNA-bind_4 PF13837.6 GBG87068.1 - 0.1 13.0 0.5 2.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SNARE_assoc PF09335.11 GBG87069.1 - 2.3e-20 73.2 5.2 2.3e-20 73.2 5.2 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein zf-CCHC PF00098.23 GBG87070.1 - 2.5e-08 33.6 2.1 4.7e-08 32.8 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Fzo_mitofusin PF04799.13 GBG87070.1 - 0.03 13.9 3.6 0.16 11.5 0.7 2.3 2 0 0 2 2 2 0 fzo-like conserved region DUF1652 PF07865.11 GBG87070.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) DUF1943 PF09172.11 GBG87070.1 - 3.2 6.9 5.2 1.9 7.7 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Spc7 PF08317.11 GBG87070.1 - 8.7 5.1 15.3 6.8 5.5 8.9 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein gag-asp_proteas PF13975.6 GBG87071.1 - 4.5e-06 27.1 0.0 9.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87071.1 - 0.0013 18.5 0.1 0.0022 17.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG87071.1 - 0.0026 18.3 0.0 0.0058 17.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87071.1 - 0.0041 16.9 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease ERCC4 PF02732.15 GBG87072.1 - 2.1e-18 67.0 0.0 3.6e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain UBA PF00627.31 GBG87072.1 - 0.035 14.0 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain CLPTM1 PF05602.12 GBG87073.1 - 1e-146 489.4 0.0 1.8e-146 488.6 0.0 1.4 2 0 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 GBG87073.1 - 0.00028 20.6 0.5 0.3 10.9 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat TMEM208_SND2 PF05620.11 GBG87073.1 - 0.13 12.0 1.2 1 9.1 0.2 2.7 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 SOR_SNZ PF01680.17 GBG87074.1 - 1.6e-112 374.3 7.9 2.4e-112 373.7 7.9 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 GBG87074.1 - 3.2e-09 36.5 4.1 2e-06 27.3 0.1 2.6 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 GBG87074.1 - 1.8e-05 24.0 0.2 0.076 12.1 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 GBG87074.1 - 0.0029 16.8 0.0 0.56 9.3 0.0 2.4 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 GBG87074.1 - 0.003 17.6 0.0 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 GBG87074.1 - 0.0035 16.6 0.4 0.27 10.4 0.0 2.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase MBF1 PF08523.10 GBG87075.1 - 8.2e-24 83.9 5.9 8.2e-24 83.9 5.9 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 GBG87075.1 - 2.5e-13 49.8 0.7 4.1e-13 49.2 0.7 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 GBG87075.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 GBG87075.1 - 0.026 14.4 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 GBG87075.1 - 0.044 13.8 0.3 0.069 13.2 0.3 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain LEA_2 PF03168.13 GBG87077.1 - 9.4e-05 22.9 0.0 0.00025 21.5 0.0 1.7 2 0 0 2 2 2 1 Late embryogenesis abundant protein Ribosom_S30AE_C PF16321.5 GBG87078.1 - 1.6e-23 82.2 0.1 2.5e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 GBG87078.1 - 2.5e-23 82.7 2.5 3.9e-23 82.0 2.5 1.3 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Ribosomal_S27e PF01667.17 GBG87078.1 - 0.012 15.3 0.5 0.036 13.8 0.5 1.7 1 0 0 1 1 1 0 Ribosomal protein S27 Mob1_phocein PF03637.17 GBG87079.1 - 1.5e-82 275.7 0.1 1.7e-82 275.5 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Plasmodium_Vir PF05795.11 GBG87079.1 - 0.016 14.6 1.0 0.026 14.0 1.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SDA1 PF05285.12 GBG87080.1 - 0.0032 17.0 39.5 0.0044 16.5 39.5 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GBG87080.1 - 0.0089 15.4 33.4 0.012 15.0 33.4 1.2 1 0 0 1 1 1 1 BUD22 BAF1_ABF1 PF04684.13 GBG87080.1 - 0.071 12.2 22.3 0.094 11.8 22.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Utp14 PF04615.13 GBG87080.1 - 0.082 11.5 31.6 0.11 11.1 31.6 1.1 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 GBG87080.1 - 0.092 11.8 10.8 0.12 11.4 10.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CCSAP PF15748.5 GBG87080.1 - 0.31 11.2 22.0 0.51 10.5 22.0 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Apt1 PF10351.9 GBG87080.1 - 0.66 8.8 8.8 0.97 8.2 8.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain LAP1C PF05609.12 GBG87080.1 - 0.78 8.8 17.8 0.97 8.4 17.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) LTV PF04180.14 GBG87080.1 - 0.86 9.3 24.0 1.4 8.6 24.0 1.3 1 0 0 1 1 1 0 Low temperature viability protein SID-1_RNA_chan PF13965.6 GBG87080.1 - 0.89 7.9 2.9 1.1 7.6 2.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S30 PF01577.16 GBG87080.1 - 1.3 8.6 17.2 2.3 7.8 17.2 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease Hid1 PF12722.7 GBG87080.1 - 5.8 4.9 21.3 7.4 4.6 21.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 GBG87080.1 - 8.2 5.1 8.1 10 4.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FRQ PF09421.10 GBG87080.1 - 9.6 4.1 15.7 14 3.5 15.7 1.2 1 0 0 1 1 1 0 Frequency clock protein TPR_2 PF07719.17 GBG87081.1 - 2.1e-05 24.3 0.4 0.0031 17.5 0.4 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG87081.1 - 0.00026 20.7 0.0 0.031 14.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Integrase_H2C2 PF17921.1 GBG87081.1 - 0.0023 18.0 0.0 0.0056 16.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Fis1_TPR_C PF14853.6 GBG87081.1 - 0.085 12.9 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF2570 PF10828.8 GBG87081.1 - 0.22 11.3 4.1 0.6 10.0 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) TPR_14 PF13428.6 GBG87081.1 - 1.9 9.5 5.3 0.71 10.9 0.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4192 PF13830.6 GBG87081.1 - 4.1 7.4 5.7 7.5 6.5 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) AAA_23 PF13476.6 GBG87082.1 - 8.1e-16 59.1 25.3 8.1e-16 59.1 25.3 9.0 1 1 3 4 4 1 1 AAA domain AAA_21 PF13304.6 GBG87082.1 - 6.3e-05 22.9 2.5 0.0015 18.4 0.0 3.1 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GBG87082.1 - 7e-05 23.0 0.0 0.00022 21.4 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 GBG87082.1 - 0.00013 21.5 0.0 0.00013 21.5 0.0 3.0 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain Rad50_zn_hook PF04423.14 GBG87082.1 - 0.00037 20.3 0.1 0.00037 20.3 0.1 6.1 7 0 0 7 7 7 1 Rad50 zinc hook motif DUF5305 PF17231.2 GBG87082.1 - 0.0036 16.7 0.5 0.012 15.1 0.5 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5305) AAA_29 PF13555.6 GBG87082.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GBG87082.1 - 0.017 15.6 0.2 0.017 15.6 0.2 7.0 3 2 0 4 4 2 0 ABC transporter AAA_13 PF13166.6 GBG87082.1 - 0.073 11.7 0.0 0.073 11.7 0.0 6.9 2 1 3 7 7 6 0 AAA domain AAA_22 PF13401.6 GBG87082.1 - 1.2 9.4 0.0 1.2 9.4 0.0 4.3 4 0 0 4 4 4 0 AAA domain DUF3293 PF11697.8 GBG87082.1 - 2.9 8.4 7.9 17 6.0 0.6 4.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3293) Rtf2 PF04641.12 GBG87083.1 - 1.6e-65 221.1 5.2 2.5e-64 217.2 5.2 2.0 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 GBG87083.1 - 0.003 17.4 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 GBG87083.1 - 0.021 14.7 1.2 0.061 13.2 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 GBG87083.1 - 0.047 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 GBG87083.1 - 0.12 12.4 0.2 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-RanBP PF00641.18 GBG87085.1 - 3.4e-09 35.8 1.3 5.1e-09 35.3 1.3 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-RanBP PF00641.18 GBG87086.1 - 3.3e-09 35.9 1.3 4.9e-09 35.3 1.3 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others LRR_6 PF13516.6 GBG87087.1 - 6.2e-12 44.6 22.7 0.04 14.0 0.0 10.8 11 0 0 11 11 11 3 Leucine Rich repeat LRR_4 PF12799.7 GBG87087.1 - 1.1e-08 35.2 5.6 1.2 9.6 0.0 7.9 7 1 4 11 11 11 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 GBG87087.1 - 1.1e-06 28.4 0.7 1.1e-06 28.4 0.7 2.8 4 0 0 4 4 4 1 F-box-like LRR_1 PF00560.33 GBG87087.1 - 0.0014 18.9 15.6 76 4.5 0.1 9.4 10 0 0 10 10 10 0 Leucine Rich Repeat F-box PF00646.33 GBG87087.1 - 0.0032 17.3 0.1 0.0032 17.3 0.1 3.0 3 0 0 3 3 3 1 F-box domain Atrophin-1 PF03154.15 GBG87087.1 - 3.1 6.0 10.6 4.4 5.5 10.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.6 GBG87087.1 - 3.8 7.5 7.4 10 6.2 7.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF1168 PF06658.12 GBG87088.1 - 2.3e-20 72.8 14.2 2.3e-20 72.8 14.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1168) BUD22 PF09073.10 GBG87088.1 - 0.002 17.6 19.9 0.0023 17.4 19.9 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 GBG87088.1 - 0.0032 15.8 30.7 0.0039 15.5 30.7 1.0 1 0 0 1 1 1 1 Nop14-like family NINJA_B PF16136.5 GBG87088.1 - 0.27 11.6 6.1 0.73 10.2 6.1 1.7 1 0 0 1 1 1 0 Putative nuclear localisation signal TFIIA PF03153.13 GBG87088.1 - 1.9 8.4 26.7 2.3 8.1 26.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pes-10 PF07149.11 GBG87088.1 - 7.4 5.5 13.1 9.4 5.2 13.1 1.2 1 0 0 1 1 1 0 Pes-10 Ribosomal_L14e PF01929.17 GBG87089.1 - 7.3e-26 90.5 2.1 1.1e-25 89.9 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 gag-asp_proteas PF13975.6 GBG87090.1 - 1.2e-05 25.7 0.2 2.6e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87090.1 - 0.00018 22.1 0.1 0.00038 21.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87090.1 - 0.0094 15.7 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG87090.1 - 0.03 14.4 1.6 0.069 13.3 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG87090.1 - 0.14 11.8 0.4 0.31 10.8 0.4 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DUF659 PF04937.15 GBG87093.1 - 3.4e-17 62.7 0.0 5.1e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG87094.1 - 9.8e-08 32.5 0.0 2.6e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87094.1 - 2.7e-05 24.7 0.0 6.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87094.1 - 0.0012 18.6 0.7 0.0024 17.6 0.7 1.4 1 0 0 1 1 1 1 Aspartyl protease RR_TM4-6 PF06459.12 GBG87094.1 - 1.3 8.8 5.1 2.3 8.0 5.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GBG87094.1 - 7.9 4.6 6.9 12 4.0 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C3HC4_3 PF13920.6 GBG87095.1 - 1.7e-09 37.4 3.9 3e-09 36.6 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG87095.1 - 2e-09 37.1 8.1 4e-09 36.2 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG87095.1 - 2.5e-09 36.9 6.3 4e-09 36.2 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG87095.1 - 4.4e-09 36.5 8.5 8.7e-09 35.6 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG87095.1 - 9.8e-09 35.1 6.0 1.2e-08 34.9 2.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG87095.1 - 3.3e-07 30.2 5.2 5.2e-07 29.5 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GBG87095.1 - 1.5e-06 28.0 5.0 2.6e-06 27.2 5.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GBG87095.1 - 3.9e-06 26.9 7.9 6.4e-06 26.2 7.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GBG87095.1 - 0.00043 20.3 1.3 0.00081 19.4 1.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GBG87095.1 - 0.0065 16.7 7.3 0.018 15.3 7.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 GBG87095.1 - 0.077 12.9 1.9 0.12 12.4 1.9 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) U-box PF04564.15 GBG87095.1 - 0.094 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 U-box domain Rtf2 PF04641.12 GBG87095.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_6 PF14835.6 GBG87095.1 - 0.26 11.2 2.5 0.48 10.3 2.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 GBG87095.1 - 0.48 10.6 3.6 0.81 9.9 3.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 GBG87095.1 - 1.9 8.4 5.8 4 7.3 5.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SOG2 PF10428.9 GBG87098.1 - 0.68 9.1 13.1 0.88 8.7 13.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RVT_1 PF00078.27 GBG87099.1 - 6.2e-25 88.0 0.1 9.8e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG87100.1 - 5.3e-06 26.6 1.1 2.7e-05 24.4 0.1 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein IBN_N PF03810.19 GBG87101.1 - 1e-15 57.4 0.0 3.7e-15 55.6 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GBG87101.1 - 1.7e-07 31.4 0.5 1.7e-07 31.4 0.5 2.6 3 0 0 3 3 3 1 Exportin 1-like protein Herpes_UL25 PF01499.16 GBG87102.1 - 1.9 6.9 8.5 4.3 5.8 8.5 1.5 1 0 0 1 1 1 0 Herpesvirus UL25 family RVT_1 PF00078.27 GBG87103.1 - 1.9e-40 138.7 3.9 2.6e-23 82.7 0.1 4.4 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87103.1 - 9.9e-29 99.3 0.0 3.2e-28 97.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87103.1 - 2.4e-27 95.3 0.0 6.7e-27 93.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG87105.1 - 2.8e-17 62.8 0.0 7.4e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87105.1 - 1.2e-06 28.3 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG87106.1 - 1.2e-08 35.3 1.7 3.3e-08 33.8 1.7 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG87106.1 - 0.0015 18.8 1.3 0.02 15.2 0.4 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG87106.1 - 0.0072 16.4 0.2 0.018 15.1 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain LapA_dom PF06305.11 GBG87106.1 - 0.084 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MAP17 PF15807.5 GBG87106.1 - 0.8 10.0 2.8 0.6 10.3 0.1 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF659 PF04937.15 GBG87108.1 - 7.7e-34 116.7 0.1 1.9e-32 112.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG87108.1 - 0.0019 18.4 4.5 0.013 15.8 0.2 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein HEAT_2 PF13646.6 GBG87108.1 - 0.074 13.5 8.3 0.38 11.2 0.0 4.0 4 0 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 GBG87108.1 - 2 9.0 7.6 1.2 9.7 0.6 3.9 4 0 0 4 4 4 0 HEAT-like repeat DUF4187 PF13821.6 GBG87108.1 - 4.9 7.0 5.4 1.2 9.0 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG87110.1 - 0.29 11.4 0.1 0.29 11.4 0.1 3.2 5 1 0 5 5 5 0 Retrotransposon gag protein FAM76 PF16046.5 GBG87110.1 - 0.96 8.7 7.8 1.4 8.2 7.8 1.2 1 0 0 1 1 1 0 FAM76 protein MRP-S26 PF14943.6 GBG87110.1 - 7.9 6.4 14.6 1e+02 2.8 12.9 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 RVT_1 PF00078.27 GBG87111.1 - 5.9e-32 111.0 0.1 4.7e-31 108.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87111.1 - 7.2e-26 90.1 0.0 1.5e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87111.1 - 1.1e-24 86.8 0.0 1.9e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG87111.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 GCR1_C PF12550.8 GBG87112.1 - 0.52 10.7 6.0 37 4.7 0.1 3.6 2 2 2 4 4 4 0 Transcriptional activator of glycolytic enzymes DUF659 PF04937.15 GBG87113.1 - 1.3e-27 96.5 0.0 2.3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG87113.1 - 0.018 15.1 0.8 0.051 13.7 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle Cwf_Cwc_15 PF04889.12 GBG87113.1 - 0.056 13.2 4.5 0.14 11.9 4.5 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 GBG87113.1 - 7.8 4.5 5.9 14 3.6 5.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi RT_RNaseH_2 PF17919.1 GBG87114.1 - 1e-25 89.6 0.0 2.5e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87114.1 - 1.4e-23 83.1 0.0 3.3e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87114.1 - 1.6e-20 73.6 0.0 2.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG87114.1 - 1.8e-07 31.7 0.0 4.9e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87114.1 - 3e-07 30.9 0.0 8.8e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87114.1 - 1.4e-05 24.8 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87114.1 - 0.00017 21.4 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG87114.1 - 0.024 14.9 0.4 0.093 13.0 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein START PF01852.19 GBG87115.1 - 4e-24 85.2 0.0 6.6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 START domain PH PF00169.29 GBG87115.1 - 1.2e-07 32.2 0.0 2.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF1336 PF07059.12 GBG87115.1 - 1.9e-05 24.9 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PH_11 PF15413.6 GBG87115.1 - 0.056 13.9 0.3 0.29 11.6 0.3 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain DUF659 PF04937.15 GBG87117.1 - 6.1e-18 65.1 0.1 2.1e-17 63.4 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87117.1 - 0.00053 19.7 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NR_Repeat PF14046.6 GBG87117.1 - 0.0034 17.5 0.2 0.01 16.0 0.2 1.7 1 0 0 1 1 1 1 Nuclear receptor repeat GMC_oxred_C PF05199.13 GBG87117.1 - 0.12 12.9 2.5 6.9 7.2 2.5 2.5 1 1 0 1 1 1 0 GMC oxidoreductase RVT_1 PF00078.27 GBG87118.1 - 2.7e-36 125.2 0.0 5e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87118.1 - 1.7e-28 99.0 0.0 4.6e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87118.1 - 7.1e-28 96.6 0.0 1.7e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SPX PF03105.19 GBG87118.1 - 0.0018 18.3 1.3 0.0018 18.3 1.3 2.5 3 0 0 3 3 3 1 SPX domain FPP PF05911.11 GBG87118.1 - 0.0032 15.7 5.2 0.0047 15.2 5.2 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil SlyX PF04102.12 GBG87118.1 - 0.0039 17.8 3.6 0.037 14.6 1.0 3.4 3 0 0 3 3 3 1 SlyX Wtap PF17098.5 GBG87118.1 - 0.18 11.8 4.7 3.9 7.4 3.3 3.0 2 1 0 2 2 2 0 WTAP/Mum2p family WXG100 PF06013.12 GBG87118.1 - 0.21 11.9 1.0 1.1 9.5 0.0 2.9 3 0 0 3 3 2 0 Proteins of 100 residues with WXG DUF4446 PF14584.6 GBG87118.1 - 0.23 11.4 1.0 0.62 10.0 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) HMMR_N PF15905.5 GBG87118.1 - 0.27 10.7 11.9 0.056 12.9 8.1 1.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Atg14 PF10186.9 GBG87118.1 - 1.5 7.8 6.4 3.6 6.6 6.4 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 GBG87118.1 - 4.7 6.0 12.0 1.1 8.1 8.0 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 GBG87118.1 - 5.2 7.4 13.1 4.9 7.5 0.6 4.0 2 1 1 3 3 3 0 ABC transporter C-terminal domain Tfb2 PF03849.14 GBG87119.1 - 2.8e-101 339.1 0.0 3.3e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 GBG87119.1 - 1.8e-22 79.5 0.1 3.7e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 GBG87119.1 - 0.0025 18.0 0.1 0.017 15.3 0.0 2.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Integrase_H2C2 PF17921.1 GBG87120.1 - 3.4e-15 55.9 0.2 8.3e-15 54.6 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG87120.1 - 1.8e-06 27.6 0.1 3.2e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87120.1 - 3.3e-06 26.9 0.0 8.1e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG87120.1 - 0.00057 20.1 0.1 0.0025 18.1 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG87120.1 - 0.0012 19.4 0.0 0.0034 18.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF4407 PF14362.6 GBG87120.1 - 0.012 15.0 0.0 0.051 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) gag-asp_proteas PF13975.6 GBG87120.1 - 0.013 16.1 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease GrpE PF01025.19 GBG87120.1 - 0.063 12.9 2.1 0.16 11.6 2.1 1.7 1 0 0 1 1 1 0 GrpE AP1AR PF15745.5 GBG87120.1 - 0.11 12.1 1.2 0.2 11.2 1.2 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein CENP-Q PF13094.6 GBG87120.1 - 0.62 10.3 8.6 1.7 8.8 8.6 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FeoC PF09012.10 GBG87121.1 - 0.073 13.1 0.0 0.34 11.0 0.0 2.1 1 0 0 1 1 1 0 FeoC like transcriptional regulator DUF21 PF01595.20 GBG87122.1 - 1.1e-16 61.0 0.5 2e-16 60.2 0.5 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain TFIIA PF03153.13 GBG87122.1 - 0.04 13.9 17.1 0.098 12.6 17.1 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid_p PF12226.8 GBG87123.1 - 2 7.5 7.0 3 6.9 7.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Merozoite_SPAM PF07133.11 GBG87123.1 - 7.1 6.6 16.5 1.2 9.1 11.9 1.8 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) RT_RNaseH_2 PF17919.1 GBG87125.1 - 1.5e-59 198.3 0.0 1.5e-28 98.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87125.1 - 8.9e-53 177.0 0.2 1.2e-25 89.9 0.2 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87125.1 - 7.8e-20 70.7 0.2 1.8e-19 69.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87125.1 - 3.3e-14 53.1 0.0 8.3e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG87125.1 - 3.4e-12 46.4 0.0 4.1e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG87125.1 - 0.00045 20.4 0.0 0.0014 18.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG87125.1 - 0.00096 19.7 0.0 0.0024 18.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87125.1 - 0.021 15.4 0.0 0.055 14.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF1564 PF07600.11 GBG87125.1 - 0.034 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) DUF2862 PF11061.8 GBG87125.1 - 0.18 11.7 0.1 0.98 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) RVT_1 PF00078.27 GBG87126.1 - 5.1e-47 160.2 3.0 9e-22 77.7 0.8 3.5 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87126.1 - 3.4e-09 36.6 0.0 0.0024 17.7 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG87126.1 - 1.3e-07 31.5 0.0 3.3e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG87126.1 - 8.1e-05 23.2 0.0 0.0032 18.1 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87126.1 - 0.0019 18.7 0.0 0.0056 17.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87126.1 - 0.0048 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG87126.1 - 0.0089 15.9 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain APG17 PF04108.12 GBG87126.1 - 0.022 13.9 0.1 6.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Autophagy protein Apg17 Retrotrans_gag PF03732.17 GBG87126.1 - 0.052 13.8 0.1 0.38 11.1 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG87127.1 - 1.4e-32 111.7 0.1 2.6e-32 110.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87127.1 - 6.2e-29 100.4 0.1 1.1e-28 99.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87127.1 - 1.5e-26 93.3 0.1 2.8e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87127.1 - 2.8e-16 59.4 0.2 7.9e-16 57.9 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87127.1 - 9.5e-13 48.4 0.0 3.2e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG87127.1 - 1.1e-08 34.9 0.0 2.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87127.1 - 1.6e-07 31.9 0.0 4e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87127.1 - 0.00021 21.8 0.0 0.00051 20.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87127.1 - 0.025 14.4 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease BSMAP PF12280.8 GBG87127.1 - 0.15 12.3 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Brain specific membrane anchored protein Integrase_H2C2 PF17921.1 GBG87128.1 - 2.7e-18 65.8 0.5 1e-17 64.0 0.2 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain DUF659 PF04937.15 GBG87128.1 - 2.3e-15 56.8 0.0 7.4e-15 55.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG87128.1 - 1.5e-14 54.1 0.0 3.5e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG87128.1 - 1.4e-07 31.7 0.0 5.4e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG87128.1 - 0.0076 16.5 0.0 0.32 11.3 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG87129.1 - 5.5e-16 58.8 0.2 6.2e-08 32.9 0.1 3.0 2 1 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG87129.1 - 6.3e-16 58.3 0.0 3.7e-15 55.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87129.1 - 2.8e-13 49.9 2.6 2.5e-08 33.7 0.2 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87129.1 - 1.9e-05 24.9 0.0 7.3e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG87129.1 - 3.3e-05 23.7 0.0 0.0042 17.0 0.0 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain MLVIN_C PF18697.1 GBG87129.1 - 0.081 13.0 0.8 19 5.4 0.0 3.5 3 0 0 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RT_RNaseH_2 PF17919.1 GBG87130.1 - 5.2e-16 58.5 0.0 1.2e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87130.1 - 4e-09 36.7 0.1 1.7e-08 34.7 0.1 2.1 1 1 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG87130.1 - 9.6e-06 25.8 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87130.1 - 0.0013 18.3 0.2 0.0024 17.4 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG87132.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG87133.1 - 2.3e-89 298.7 8.7 2.9e-27 95.6 0.0 4.5 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87133.1 - 1e-81 269.3 0.0 6.3e-32 109.6 0.0 3.9 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87133.1 - 3e-80 265.3 0.5 3.7e-28 97.9 0.0 3.9 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87133.1 - 2.8e-66 219.5 16.1 5.8e-16 58.3 0.1 4.7 4 0 0 4 4 4 4 Integrase zinc binding domain rve PF00665.26 GBG87133.1 - 1e-52 177.3 3.6 3.1e-15 56.4 0.1 5.9 5 0 0 5 5 5 5 Integrase core domain Retrotrans_gag PF03732.17 GBG87133.1 - 1.5e-15 57.2 7.6 0.12 12.6 0.0 6.4 5 0 0 5 5 5 5 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG87133.1 - 5.5e-15 55.3 5.5 0.028 14.6 0.1 5.0 4 0 0 4 4 4 4 H2C2 zinc finger RVP_2 PF08284.11 GBG87133.1 - 6.2e-13 48.7 0.0 2.1e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87133.1 - 7.5e-13 48.9 0.0 6.5e-05 23.5 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG87133.1 - 1.2e-12 48.2 0.0 5.6e-05 23.6 0.0 3.1 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87133.1 - 6.9e-07 29.1 0.0 0.056 13.2 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease DUF5066 PF16728.5 GBG87133.1 - 0.044 13.1 0.9 13 5.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5066) zf-CCHC_3 PF13917.6 GBG87133.1 - 0.08 12.9 4.3 0.035 14.1 1.0 2.1 2 0 0 2 2 2 0 Zinc knuckle NIR_SIR PF01077.22 GBG87133.1 - 0.17 11.4 3.3 31 4.0 0.2 3.8 4 0 0 4 4 4 0 Nitrite and sulphite reductase 4Fe-4S domain zf-CCHC PF00098.23 GBG87133.1 - 3.6 7.8 4.8 11 6.2 4.8 2.0 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG87134.1 - 7.4e-18 64.9 0.0 1.6e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87134.1 - 2.3e-16 60.0 0.1 5.4e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87134.1 - 2e-13 50.6 0.1 8e-13 48.6 0.1 2.1 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG87134.1 - 6.5e-09 35.7 0.1 1.5e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG87134.1 - 0.0036 17.5 3.4 1.5 9.1 0.0 4.1 4 0 0 4 4 4 2 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG87135.1 - 6.2e-29 100.4 0.9 2.1e-28 98.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87135.1 - 1.6e-27 95.4 0.1 7.2e-27 93.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG87135.1 - 1.8e-17 63.6 1.2 2.6e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87135.1 - 0.00017 21.3 2.7 0.0021 17.8 0.0 3.6 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG87135.1 - 0.0048 16.4 0.1 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sirohm_synth_M PF14824.6 GBG87135.1 - 0.16 11.4 0.0 0.45 10.0 0.0 1.9 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central DUF659 PF04937.15 GBG87137.1 - 1.9e-25 89.5 0.0 4.9e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG87137.1 - 9.1e-11 42.0 0.0 2.9e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG87137.1 - 2.4e-06 27.3 0.4 6.9e-06 25.8 0.4 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG87138.1 - 1.2e-26 93.6 0.1 2.4e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87138.1 - 1.3e-18 66.8 0.0 3.5e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87138.1 - 1.6e-09 38.0 0.0 3.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DAG_kinase_N PF14513.6 GBG87138.1 - 0.023 14.9 1.8 0.052 13.8 1.8 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus CHASE6_C PF17150.4 GBG87138.1 - 3 8.6 7.2 1.3e+02 3.3 0.1 3.7 3 1 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain DUF1840 PF08895.11 GBG87138.1 - 3.6 8.0 14.3 1.3 9.4 10.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) RVT_1 PF00078.27 GBG87140.1 - 0.00063 19.3 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG87140.1 - 0.00078 20.0 0.0 0.0019 18.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87140.1 - 0.0028 18.3 0.0 0.0072 16.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG87140.1 - 0.0066 16.7 0.2 0.027 14.7 0.1 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein RVP PF00077.20 GBG87140.1 - 0.017 15.4 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease CD99L2 PF12301.8 GBG87140.1 - 0.39 11.0 0.0 0.39 11.0 0.0 2.9 3 0 0 3 3 3 0 CD99 antigen like protein 2 RVT_1 PF00078.27 GBG87141.1 - 3.6e-31 108.4 0.1 6.6e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87141.1 - 4e-20 71.7 0.6 4.9e-19 68.2 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87141.1 - 4.9e-08 33.2 0.0 6.5e-07 29.6 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RP-C_C PF11800.8 GBG87141.1 - 0.0051 16.9 4.6 1.3 9.1 0.1 2.6 2 0 0 2 2 2 2 Replication protein C C-terminal region Spc29 PF17082.5 GBG87141.1 - 0.029 14.2 0.3 0.029 14.2 0.3 1.7 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF4187 PF13821.6 GBG87141.1 - 0.043 13.6 1.3 0.19 11.5 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) CCDC85 PF10226.9 GBG87141.1 - 0.068 12.9 0.2 0.068 12.9 0.2 2.2 3 0 0 3 3 3 0 CCDC85 family LOH1CR12 PF10158.9 GBG87141.1 - 0.084 12.9 0.4 0.32 11.0 0.4 2.0 1 0 0 1 1 1 0 Tumour suppressor protein Fez1 PF06818.15 GBG87141.1 - 0.093 13.2 7.4 0.043 14.3 2.2 2.6 2 0 0 2 2 2 0 Fez1 DUF4806 PF16064.5 GBG87141.1 - 0.15 12.4 0.2 0.5 10.7 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) DUF2730 PF10805.8 GBG87141.1 - 0.4 10.8 7.6 0.33 11.0 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) ABC_tran_CTD PF16326.5 GBG87141.1 - 1.5 9.2 9.2 0.59 10.4 1.3 3.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 GBG87141.1 - 5.5 7.5 10.4 2.6 8.5 1.4 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) T3SSipB PF16535.5 GBG87141.1 - 6.3 7.3 12.2 0.17 12.4 3.4 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB XhlA PF10779.9 GBG87141.1 - 7.5 6.8 9.4 1.2 9.4 0.2 3.0 3 0 0 3 3 2 0 Haemolysin XhlA Phage_GPO PF05929.11 GBG87141.1 - 9.5 5.8 9.4 3.2 7.3 3.2 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Dimer_Tnp_hAT PF05699.14 GBG87142.1 - 1e-08 34.8 0.5 2e-08 33.9 0.5 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4187 PF13821.6 GBG87143.1 - 0.01 15.6 0.7 0.029 14.2 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG87143.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.4 3 0 0 3 3 3 0 Retrotransposon gag protein DUF3143 PF11341.8 GBG87144.1 - 0.05 14.0 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) PA26 PF04636.13 GBG87144.1 - 3.4 6.5 10.5 3.8 6.3 10.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM60A PF15396.6 GBG87144.1 - 5 7.1 9.0 5.3 7.0 9.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Integrase_H2C2 PF17921.1 GBG87145.1 - 1e-16 60.8 0.4 2.6e-16 59.5 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG87145.1 - 5.3e-12 45.6 0.0 1.4e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87145.1 - 6.1e-09 36.1 0.0 1.9e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG87145.1 - 1.9e-08 34.2 0.0 4.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG87145.1 - 5.5e-08 33.0 0.0 1.6e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG87145.1 - 1.4e-07 32.0 0.0 3.7e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG87145.1 - 1.7e-06 27.8 0.1 8e-05 22.3 0.0 2.4 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG87145.1 - 7.9e-06 26.3 0.0 2.6e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG87145.1 - 0.00053 20.2 0.1 0.0014 18.8 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG87145.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG87145.1 - 0.027 14.8 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 1 0 Retrotransposon gag protein PDEase_II PF02112.15 GBG87145.1 - 0.087 11.9 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Cnl2_NKP2 PF09447.10 GBG87145.1 - 0.09 12.9 0.0 4.3 7.5 0.0 2.9 2 0 0 2 2 2 0 Cnl2/NKP2 family protein SlyX PF04102.12 GBG87145.1 - 2.2 9.0 5.9 0.43 11.2 0.1 3.0 2 0 0 2 2 1 0 SlyX RVT_1 PF00078.27 GBG87146.1 - 2.8e-19 69.5 0.3 5.3e-19 68.6 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4228 PF14009.6 GBG87147.1 - 9.4 6.6 12.0 10 6.5 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Adaptin_N PF01602.20 GBG87148.1 - 1.1e-92 311.4 0.0 1.4e-92 310.9 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GBG87148.1 - 0.0036 17.4 1.5 0.0099 15.9 0.1 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GBG87148.1 - 0.011 16.1 0.3 0.011 16.1 0.3 3.0 4 0 0 4 4 4 0 HEAT repeats HEAT PF02985.22 GBG87148.1 - 0.036 14.3 1.7 1.5 9.3 0.2 3.7 3 0 0 3 3 3 0 HEAT repeat BLUF PF04940.12 GBG87149.1 - 0.02 15.0 0.0 0.063 13.4 0.0 2.0 1 1 0 1 1 1 0 Sensors of blue-light using FAD DUF4357 PF14267.6 GBG87150.1 - 1.8 8.5 6.4 2.2 8.3 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) Bestrophin PF01062.21 GBG87152.1 - 5e-39 134.4 2.3 1.2e-38 133.2 0.7 2.1 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel RT_RNaseH_2 PF17919.1 GBG87152.1 - 4.8e-26 90.7 0.0 1.1e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87152.1 - 1.1e-22 80.2 0.0 2.2e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87152.1 - 1.7e-10 40.8 0.1 3.9e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-DNL PF05180.12 GBG87153.1 - 1.8e-15 56.6 0.0 5.1e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 DNL zinc finger LRIF1 PF15741.5 GBG87154.1 - 4.4 5.7 13.4 5.8 5.3 13.4 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 SLC12 PF03522.15 GBG87154.1 - 7.7 5.4 14.4 10 5.0 14.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 UAA PF08449.11 GBG87156.1 - 2.9e-71 240.2 5.0 3.3e-71 240.0 5.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GBG87156.1 - 2e-08 34.5 15.6 6.4e-05 23.1 2.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 GBG87156.1 - 0.0038 16.8 1.3 0.0038 16.8 1.3 1.5 2 0 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 GBG87156.1 - 0.015 14.2 1.4 0.027 13.4 1.4 1.5 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Abhydrolase_2 PF02230.16 GBG87157.1 - 1.2e-36 126.6 0.0 3.1e-36 125.2 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GBG87157.1 - 7.5e-06 25.4 0.1 0.011 15.0 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 GBG87157.1 - 2e-05 24.4 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 GBG87157.1 - 0.00058 19.5 2.6 0.0044 16.6 0.5 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GBG87157.1 - 0.016 14.7 0.1 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF4320 PF14208.6 GBG87158.1 - 0.014 15.4 1.4 0.034 14.2 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) DUF481 PF04338.12 GBG87158.1 - 0.022 14.8 0.2 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF481 LEA_2 PF03168.13 GBG87158.1 - 0.37 11.4 3.2 0.79 10.3 3.2 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein FixG_C PF11614.8 GBG87158.1 - 0.37 11.0 4.6 0.67 10.2 4.6 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Coatomer_g_Cpla PF16381.5 GBG87158.1 - 0.89 9.7 11.3 0.22 11.7 5.3 2.6 2 0 0 2 2 2 0 Coatomer subunit gamma-1 C-terminal appendage platform DUF1943 PF09172.11 GBG87158.1 - 3.3 6.9 6.2 6.1 6.0 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) CTP_transf_like PF01467.26 GBG87159.1 - 0.11 12.7 0.5 0.23 11.6 0.5 1.6 1 0 0 1 1 1 0 Cytidylyltransferase-like DUF2894 PF11445.8 GBG87159.1 - 2.1 8.8 5.9 1 9.8 1.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) TPR_12 PF13424.6 GBG87160.1 - 2.2e-16 59.9 0.1 2.9e-07 30.7 0.0 3.5 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG87160.1 - 6.5e-16 57.4 4.7 1.6e-07 30.8 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG87160.1 - 2.1e-12 46.1 2.9 0.00062 19.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG87160.1 - 7.5e-10 39.2 0.1 0.0016 18.9 0.0 3.0 2 1 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG87160.1 - 1e-08 34.6 0.0 0.054 13.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.6 GBG87160.1 - 1.7e-08 34.2 0.4 3.4e-08 33.3 0.4 1.6 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 GBG87160.1 - 4.4e-08 33.3 1.9 0.62 10.8 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG87160.1 - 2.2e-07 31.4 0.0 0.026 15.2 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG87160.1 - 2e-06 27.5 8.1 0.69 10.3 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 GBG87160.1 - 6e-06 26.1 1.0 9.8e-06 25.4 1.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 GBG87160.1 - 1.9e-05 24.2 0.1 0.0013 18.4 0.1 3.2 3 0 0 3 3 3 1 TPR repeat DUF3808 PF10300.9 GBG87160.1 - 4.4e-05 22.4 0.4 8.2e-05 21.5 0.2 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3808) TPR_10 PF13374.6 GBG87160.1 - 0.00023 20.9 0.2 0.08 12.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 GBG87160.1 - 0.00025 21.3 1.0 0.015 15.6 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG87160.1 - 0.00041 20.9 0.0 0.41 11.6 0.0 4.1 3 2 2 5 5 4 1 Tetratricopeptide repeat Foie-gras_1 PF11817.8 GBG87160.1 - 0.00045 19.9 0.7 0.31 10.6 0.3 2.4 1 1 1 2 2 2 2 Foie gras liver health family 1 TPR_3 PF07720.12 GBG87160.1 - 0.00089 19.2 2.6 7.7 6.6 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG87160.1 - 0.0013 18.9 0.3 0.12 12.6 0.1 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 GBG87160.1 - 0.012 15.0 0.1 0.048 13.0 0.0 1.8 1 1 1 2 2 2 0 MalT-like TPR region SPO22 PF08631.10 GBG87160.1 - 0.017 14.7 0.0 2.4 7.6 0.0 2.6 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like MIT PF04212.18 GBG87160.1 - 0.024 14.7 4.1 8.9 6.5 0.0 4.5 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain PPR_2 PF13041.6 GBG87160.1 - 0.048 13.9 0.3 75 3.6 0.0 4.0 4 0 0 4 4 4 0 PPR repeat family TPR_17 PF13431.6 GBG87160.1 - 0.055 13.9 1.9 17 6.0 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat HemY_N PF07219.13 GBG87160.1 - 0.13 12.5 1.2 0.57 10.4 0.7 2.2 2 0 0 2 2 2 0 HemY protein N-terminus Retrotrans_gag PF03732.17 GBG87161.1 - 0.0042 17.3 0.0 0.015 15.5 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein DUF3251 PF11622.8 GBG87161.1 - 0.012 15.3 0.5 0.89 9.2 0.1 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF3251) SlyX PF04102.12 GBG87161.1 - 0.035 14.7 2.6 0.14 12.8 0.4 2.8 2 1 1 3 3 3 0 SlyX Med9 PF07544.13 GBG87161.1 - 0.23 11.6 1.3 3.4 7.8 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TPR_2 PF07719.17 GBG87162.1 - 3e-14 51.9 3.6 4e-05 23.4 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG87162.1 - 4.3e-13 48.5 3.9 1.8e-05 24.3 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG87162.1 - 1.4e-11 43.6 1.1 0.00054 20.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG87162.1 - 1.5e-10 41.2 1.6 3.5e-06 27.2 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG87162.1 - 1.9e-09 38.0 0.5 5.2e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG87162.1 - 2.4e-08 33.5 2.3 7.1e-06 25.6 0.2 2.6 2 1 1 3 3 3 2 TPR repeat TPR_6 PF13174.6 GBG87162.1 - 4.4e-08 33.2 0.2 0.0044 17.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG87162.1 - 1.7e-06 28.4 0.3 0.001 19.5 0.1 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GBG87162.1 - 4.7e-06 26.3 1.9 0.51 10.3 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG87162.1 - 7.3e-05 22.9 0.2 0.00011 22.4 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 GBG87162.1 - 0.00032 20.5 0.1 0.00098 18.9 0.1 1.7 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 GBG87162.1 - 0.0006 19.7 0.2 0.7 10.1 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GBG87162.1 - 0.00072 19.8 3.2 0.5 10.9 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG87162.1 - 0.0024 17.3 0.0 1.3 8.3 0.0 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 GBG87162.1 - 0.0052 17.3 0.0 35 5.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG87162.1 - 0.0059 17.3 0.1 7 7.8 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 GBG87162.1 - 0.059 13.1 0.1 10 5.8 0.1 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 HemY_N PF07219.13 GBG87162.1 - 7 6.9 6.8 0.6 10.3 0.1 2.5 2 1 0 2 2 1 0 HemY protein N-terminus DDE_Tnp_4 PF13359.6 GBG87164.1 - 6.8e-31 107.1 0.0 2e-30 105.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87164.1 - 1.5e-13 50.9 0.0 2.4e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG87164.1 - 0.005 16.5 0.8 4.2 7.0 0.1 3.1 3 0 0 3 3 3 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG87165.1 - 5.7e-10 39.4 0.8 7.4e-09 35.9 0.6 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG87165.1 - 0.0056 16.7 1.4 0.015 15.3 1.4 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG87166.1 - 4.9e-05 23.6 0.5 9.9e-05 22.6 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DctP PF03480.13 GBG87167.1 - 5.2e-16 58.8 0.0 1.4e-15 57.5 0.0 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein, family 7 Phage_holin_1 PF04531.13 GBG87168.1 - 1.9 9.0 7.6 0.62 10.6 4.4 1.8 2 0 0 2 2 2 0 Bacteriophage holin PAS_6 PF08348.11 GBG87169.1 - 0.032 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 YheO-like PAS domain RT_RNaseH_2 PF17919.1 GBG87170.1 - 6.3e-09 35.8 0.0 9.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87170.1 - 6.8e-07 29.0 0.1 9.4e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87170.1 - 0.0066 16.7 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG87170.1 - 0.13 11.4 0.0 0.24 10.4 0.0 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 Nop14 PF04147.12 GBG87171.1 - 0.98 7.6 26.8 1.3 7.1 26.8 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 GBG87171.1 - 1.3 9.1 30.3 2 8.5 30.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG87171.1 - 2.4 7.4 31.7 3.4 6.9 31.7 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG87171.1 - 5.3 6.4 29.9 7.2 5.9 29.9 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG87171.1 - 5.9 6.4 14.0 8.6 5.8 14.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Vfa1 PF08432.10 GBG87171.1 - 7.1 6.9 14.5 12 6.2 14.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 GBG87171.1 - 8.4 4.6 23.5 11 4.2 23.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG87172.1 - 1.9e-26 92.0 0.0 4.4e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87172.1 - 1.3e-24 86.5 0.0 2.9e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG87172.1 - 0.0063 16.8 0.2 0.038 14.2 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG87172.1 - 0.75 9.1 16.6 1.8 7.9 11.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 GBG87172.1 - 1.6 7.5 11.3 3.1 6.6 11.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein RT_RNaseH_2 PF17919.1 GBG87173.1 - 5.7e-21 74.4 0.0 1.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87173.1 - 2.4e-12 47.0 0.0 4.8e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87173.1 - 5.9e-11 42.3 0.0 1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87173.1 - 9.7e-10 38.3 0.0 8.6e-09 35.3 0.0 2.5 2 1 1 3 3 3 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87173.1 - 7e-08 33.0 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87173.1 - 4.7e-06 27.1 0.0 1.1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG87173.1 - 0.041 14.2 0.5 0.64 10.3 0.2 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein APG17 PF04108.12 GBG87173.1 - 0.041 13.0 0.0 0.58 9.2 0.0 2.3 2 0 0 2 2 2 0 Autophagy protein Apg17 Spectrin PF00435.21 GBG87173.1 - 0.12 12.9 1.4 9.4 6.8 0.0 3.3 3 0 0 3 3 3 0 Spectrin repeat MerR_2 PF13591.6 GBG87173.1 - 3.5 7.5 6.1 4.4 7.2 0.5 3.4 4 0 0 4 4 4 0 MerR HTH family regulatory protein DDE_Tnp_4 PF13359.6 GBG87175.1 - 7.1e-27 94.0 0.0 9.8e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87175.1 - 7.1e-15 55.2 0.0 1.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG87175.1 - 0.0091 15.7 0.7 4.1 7.0 0.4 2.4 2 0 0 2 2 2 2 Transposase DDE domain DUF4834 PF16118.5 GBG87177.1 - 0.15 13.0 0.0 0.3 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RT_RNaseH PF17917.1 GBG87178.1 - 3.9e-22 78.5 0.0 1.1e-21 77.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87178.1 - 1.3e-21 76.5 0.0 2.7e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG87178.1 - 2.6e-06 27.9 0.1 8.6e-06 26.2 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87178.1 - 6.4e-05 23.5 0.1 0.00017 22.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87178.1 - 0.00042 20.1 0.1 0.00099 18.9 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG87178.1 - 0.00052 19.6 0.0 0.094 12.2 0.0 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87178.1 - 0.03 14.1 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG87178.1 - 0.1 12.7 1.9 0.18 11.9 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG87179.1 - 1.1e-07 32.3 0.1 2.6e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87179.1 - 1.7e-05 25.3 0.1 4.4e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87179.1 - 0.00017 21.4 0.2 0.00045 20.0 0.2 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG87179.1 - 0.0023 17.5 0.0 0.25 10.8 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87179.1 - 0.0044 16.8 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG87181.1 - 4.6e-29 101.5 0.2 7.8e-29 100.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87181.1 - 2.2e-23 82.2 0.0 4.5e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87181.1 - 2.2e-21 76.1 0.0 3.8e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87181.1 - 1.2e-15 57.4 5.5 1.2e-15 57.4 0.4 3.1 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG87181.1 - 0.0019 18.3 0.2 0.0054 16.9 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Intron_maturas2 PF01348.21 GBG87182.1 - 0.0083 16.1 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 Type II intron maturase Kinesin PF00225.23 GBG87183.1 - 5.9e-103 344.3 0.0 9.9e-103 343.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG87183.1 - 1.3e-22 80.3 0.2 2.5e-21 76.2 0.0 3.0 3 0 0 3 3 3 1 Microtubule binding Hom_end_hint PF05203.16 GBG87183.1 - 0.0048 16.9 0.0 0.0097 15.9 0.0 1.6 1 0 0 1 1 1 1 Hom_end-associated Hint Bap31_Bap29_C PF18035.1 GBG87183.1 - 0.026 14.5 0.0 0.026 14.5 0.0 4.6 4 1 1 5 5 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain MTCP1 PF08991.10 GBG87184.1 - 1.4e-13 50.8 5.2 2.3e-13 50.1 5.2 1.4 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type tRNA_int_endo PF01974.17 GBG87185.1 - 8.3e-21 73.9 0.0 1.5e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 GBG87185.1 - 0.00068 19.2 0.0 0.021 14.5 0.1 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain EGF_3 PF12947.7 GBG87186.1 - 0.057 13.6 4.5 0.19 12.0 4.5 1.9 1 0 0 1 1 1 0 EGF domain Xpo1 PF08389.12 GBG87187.1 - 8.8e-32 110.2 0.0 1.4e-30 106.3 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 GBG87187.1 - 0.00078 19.5 0.6 2.5 8.6 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat CAS_CSE1 PF03378.15 GBG87187.1 - 0.043 12.3 0.1 2.8 6.3 0.0 3.2 3 1 0 3 3 3 0 CAS/CSE protein, C-terminus Esterase_phd PF10503.9 GBG87187.1 - 0.056 12.9 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Urb2 PF10441.9 GBG87187.1 - 0.11 12.4 0.1 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Urb2/Npa2 family Ribosomal_60s PF00428.19 GBG87187.1 - 8.6 7.0 6.5 0.86 10.2 0.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein RecA PF00154.21 GBG87189.1 - 1.5e-113 378.6 0.2 2e-113 378.2 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 GBG87189.1 - 1.4e-10 40.9 0.0 1e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 GBG87189.1 - 1.2e-08 34.6 0.1 7.8e-08 31.9 0.1 2.2 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 GBG87189.1 - 5.7e-06 26.0 0.1 3.1e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GBG87189.1 - 0.0002 21.1 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GBG87189.1 - 0.0016 18.4 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DnaB_C PF03796.15 GBG87189.1 - 0.014 14.8 0.0 0.22 10.8 0.0 2.1 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain AAA_35 PF14516.6 GBG87189.1 - 0.072 11.9 0.1 0.2 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.14 GBG87189.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4702 PF15774.5 GBG87189.1 - 0.86 8.5 4.9 1.5 7.6 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) MFS_5 PF05631.14 GBG87190.1 - 1.6e-156 520.7 14.3 2e-156 520.3 14.3 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GBG87190.1 - 2e-19 69.8 27.8 4.3e-18 65.4 21.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5455 PF17537.2 GBG87190.1 - 0.27 11.6 5.7 3.5 8.1 0.2 3.9 2 1 2 4 4 4 0 Family of unknown function (DUF5455) DuoxA PF10204.9 GBG87190.1 - 4.3 6.3 12.5 0.087 11.8 4.0 2.4 3 0 0 3 3 3 0 Dual oxidase maturation factor Trm112p PF03966.16 GBG87191.1 - 1.8e-17 63.7 0.1 2.5e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein DUF2407_C PF13373.6 GBG87192.1 - 0.18 12.0 1.6 0.28 11.3 1.1 1.6 1 1 0 1 1 1 0 DUF2407 C-terminal domain BST2 PF16716.5 GBG87192.1 - 4.4 8.0 9.8 1 10.0 3.6 2.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 BAF1_ABF1 PF04684.13 GBG87195.1 - 1.4 7.9 6.8 1.9 7.5 6.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor gag-asp_proteas PF13975.6 GBG87196.1 - 9.9e-05 22.8 0.0 0.00017 22.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87196.1 - 0.00014 22.4 0.0 0.00028 21.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG87196.1 - 0.0079 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG87196.1 - 0.024 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease AAA_23 PF13476.6 GBG87197.1 - 0.49 10.9 17.7 0.46 11.0 6.4 2.5 2 0 0 2 2 2 0 AAA domain Podoplanin PF05808.11 GBG87198.1 - 0.0059 16.7 20.6 0.055 13.6 4.7 3.3 1 1 2 3 3 3 3 Podoplanin DUF4686 PF15742.5 GBG87198.1 - 0.24 10.5 5.5 1.8 7.6 1.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4686) Vps26 PF03643.15 GBG87199.1 - 4.9e-25 88.1 1.3 1.8e-17 63.3 0.3 2.5 2 1 0 2 2 2 2 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GBG87199.1 - 4.7e-05 23.5 0.0 0.00039 20.5 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GBG87199.1 - 0.0077 16.7 0.1 0.12 12.8 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Ribosomal_L27 PF01016.19 GBG87200.1 - 4.2e-36 122.8 1.1 6.4e-36 122.2 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein SPRY PF00622.28 GBG87200.1 - 0.062 13.4 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 SPRY domain DUF2854 PF11016.8 GBG87201.1 - 3.8e-47 159.9 0.0 5.3e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) SR-25 PF10500.9 GBG87201.1 - 0.054 13.1 5.9 0.08 12.5 5.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2273 PF10031.9 GBG87201.1 - 5.1 7.2 9.7 1.4 8.9 3.9 2.3 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) RT_RNaseH_2 PF17919.1 GBG87202.1 - 1.3e-34 118.2 0.1 3.7e-34 116.8 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87202.1 - 5.9e-30 103.7 1.5 7.6e-30 103.3 0.2 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87202.1 - 9.8e-27 93.9 0.1 1.9e-26 93.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87202.1 - 2.8e-19 69.0 0.2 5.9e-19 67.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87202.1 - 3.7e-16 59.4 0.0 1.4e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG87202.1 - 9.8e-06 26.0 0.0 5.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87202.1 - 0.00072 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87202.1 - 0.0021 18.6 0.0 0.0056 17.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1564 PF07600.11 GBG87202.1 - 0.027 14.2 0.0 0.085 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-H2C2 PF09337.10 GBG87202.1 - 0.06 13.6 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger DUF1758 PF05585.12 GBG87202.1 - 0.071 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Gpi16 PF04113.14 GBG87203.1 - 3.5e-140 468.1 0.0 1.5e-92 310.9 0.0 3.1 2 1 0 2 2 2 2 Gpi16 subunit, GPI transamidase component LSM PF01423.22 GBG87204.1 - 5.8e-20 70.7 0.6 7.4e-20 70.4 0.6 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 GBG87204.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Nup35_RRM PF05172.13 GBG87206.1 - 6.8e-14 51.7 0.0 1.1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 GBG87206.1 - 9.3e-05 22.3 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 GBG87206.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) gag-asp_proteas PF13975.6 GBG87207.1 - 0.00029 21.3 0.4 0.0011 19.5 0.1 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87207.1 - 0.0078 16.8 0.0 0.028 15.1 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease DUF1048 PF06304.11 GBG87207.1 - 0.016 15.7 0.1 0.057 13.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) RVP PF00077.20 GBG87207.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease SDA1 PF05285.12 GBG87208.1 - 0.0033 16.9 52.7 0.0046 16.4 52.7 1.3 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GBG87208.1 - 2.1 7.6 54.4 2.8 7.2 54.4 1.2 1 0 0 1 1 1 0 BUD22 Rgp1 PF08737.10 GBG87208.1 - 2.2 7.4 6.6 2.9 7.0 6.6 1.3 1 0 0 1 1 1 0 Rgp1 Utp14 PF04615.13 GBG87208.1 - 3.7 6.0 49.9 4.7 5.7 49.9 1.1 1 0 0 1 1 1 0 Utp14 protein Mitofilin PF09731.9 GBG87208.1 - 7.3 5.3 33.5 9 5.0 33.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ABC_tran PF00005.27 GBG87209.1 - 6.4e-25 88.3 0.0 1.4e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GBG87209.1 - 3.4e-16 59.3 19.4 4.5e-16 58.9 19.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GBG87209.1 - 6.4e-10 39.3 0.0 5.6e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GBG87209.1 - 0.044 13.2 0.0 1.2 8.5 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 GBG87209.1 - 0.066 12.6 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TT_ORF1 PF02956.14 GBG87209.1 - 0.29 9.8 16.0 0.47 9.1 16.0 1.3 1 0 0 1 1 1 0 TT viral orf 1 Apt1 PF10351.9 GBG87209.1 - 0.35 9.7 6.3 0.5 9.2 6.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop53 PF07767.11 GBG87209.1 - 4.3 6.6 51.0 6.6 6.0 51.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) End3 PF12761.7 GBG87210.1 - 0.084 13.0 5.9 0.11 12.7 5.9 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 CDC45 PF02724.14 GBG87210.1 - 6.3 5.0 11.8 6.8 4.9 11.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH PF17917.1 GBG87212.1 - 2e-19 69.8 0.5 4.8e-19 68.6 0.5 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PWI PF01480.17 GBG87212.1 - 1.5e-15 57.3 1.5 5.3e-15 55.5 1.5 2.1 1 0 0 1 1 1 1 PWI domain Integrase_H2C2 PF17921.1 GBG87212.1 - 6.7e-14 51.7 0.0 1.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG87212.1 - 1.2e-11 44.5 0.1 3.3e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG87212.1 - 0.042 14.1 1.0 0.57 10.4 0.0 3.2 4 0 0 4 4 4 0 H2C2 zinc finger rve PF00665.26 GBG87212.1 - 0.049 13.8 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG87213.1 - 3.9e-73 245.6 2.0 9.8e-30 103.7 0.0 4.7 5 0 0 5 5 5 4 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG87213.1 - 4.3e-19 68.9 0.0 2.7e-09 37.3 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG87213.1 - 6.5e-10 38.9 0.0 4.4e-08 33.1 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87213.1 - 5.7e-08 32.8 0.6 1.4e-07 31.5 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG87213.1 - 9.3e-06 25.9 0.0 0.088 13.1 0.1 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG87213.1 - 2.9e-05 24.3 8.2 0.063 13.6 0.1 5.0 4 0 0 4 4 4 2 Retrotransposon gag protein RVP_2 PF08284.11 GBG87213.1 - 0.00016 21.5 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG87213.1 - 0.00019 21.1 0.2 0.00059 19.6 0.2 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Asp_protease_2 PF13650.6 GBG87213.1 - 0.089 13.4 0.0 0.27 11.9 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease FAM178 PF14816.6 GBG87213.1 - 3.2 6.6 5.8 7.3 5.5 5.8 1.5 1 0 0 1 1 1 0 Family of unknown function, FAM178 rve PF00665.26 GBG87216.1 - 5.1e-15 55.7 0.0 9.1e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG87216.1 - 0.0016 18.2 0.0 0.0051 16.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 GBG87217.1 - 2.1e-08 34.4 0.0 5.4e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG87217.1 - 0.0017 18.1 0.0 0.0047 16.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Beta_helix PF13229.6 GBG87218.1 - 1e-06 28.7 1.2 1.6e-06 28.1 1.2 1.3 1 0 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG87218.1 - 0.0028 18.0 0.3 0.0028 18.0 0.3 6.2 6 1 0 6 6 6 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF659 PF04937.15 GBG87219.1 - 3.1e-29 101.8 0.2 5.2e-29 101.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87219.1 - 3.8e-05 23.4 0.1 0.00013 21.7 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AAA PF00004.29 GBG87220.1 - 3.9e-13 50.0 0.0 8.9e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 GBG87220.1 - 2.4e-06 26.8 0.0 9.9e-05 21.8 0.0 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_14 PF13173.6 GBG87220.1 - 0.0024 17.9 0.0 0.0077 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Cript PF10235.9 GBG87221.1 - 1.2e-33 115.5 12.2 2e-33 114.8 12.2 1.3 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DUF1272 PF06906.11 GBG87221.1 - 0.00098 19.2 7.3 0.0036 17.4 5.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) DZR PF12773.7 GBG87221.1 - 0.018 15.1 6.9 0.018 15.1 6.9 2.4 2 1 0 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 GBG87221.1 - 0.06 13.6 6.6 1.4 9.2 0.8 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_2 PF13240.6 GBG87221.1 - 0.074 12.8 5.4 4.2 7.2 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 GBG87221.1 - 0.077 13.8 10.4 0.09 13.5 6.6 2.3 2 1 0 2 2 2 0 zinc-ribbon family DUF2039 PF10217.9 GBG87221.1 - 0.69 10.3 17.0 1.4 9.3 17.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) C1_1 PF00130.22 GBG87221.1 - 1.3 8.9 13.4 0.56 10.1 5.7 2.8 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 GBG87221.1 - 3.3 7.7 13.2 0.96 9.4 3.3 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 SnoaL_2 PF12680.7 GBG87222.1 - 0.00012 22.6 0.2 0.0022 18.6 0.0 2.4 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 GBG87222.1 - 0.016 15.0 0.3 0.053 13.3 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase DUF4440 PF14534.6 GBG87222.1 - 0.045 14.1 0.0 0.093 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Ring_hydroxyl_B PF00866.18 GBG87222.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Ring hydroxylating beta subunit MAM33 PF02330.16 GBG87224.1 - 2.1e-23 83.4 0.0 2.1e-23 83.4 0.0 4.6 2 1 1 4 4 4 2 Mitochondrial glycoprotein FAM176 PF14851.6 GBG87224.1 - 0.0003 20.5 0.5 0.0003 20.5 0.5 4.7 2 2 1 3 3 3 1 FAM176 family GRP PF07172.11 GBG87224.1 - 0.00049 20.7 18.6 0.012 16.3 15.7 2.6 2 0 0 2 2 2 1 Glycine rich protein family Orf78 PF06024.12 GBG87224.1 - 0.0048 17.2 0.0 0.0048 17.2 0.0 2.9 3 0 0 3 3 3 1 Orf78 (ac78) LRRC37AB_C PF14914.6 GBG87224.1 - 0.42 10.5 0.0 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain BUD22 PF09073.10 GBG87224.1 - 1.9 7.8 61.7 0.018 14.4 17.2 2.1 2 0 0 2 2 2 0 BUD22 RNA_pol_Rpb2_6 PF00562.28 GBG87225.1 - 4.2e-125 417.8 0.0 7.3e-125 417.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GBG87225.1 - 3.7e-71 238.8 0.0 5.7e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 GBG87225.1 - 5.5e-46 156.6 0.0 1.8e-45 154.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GBG87225.1 - 4e-35 120.1 0.2 1.3e-34 118.5 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 GBG87225.1 - 3.1e-25 88.1 0.1 6.7e-25 87.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 GBG87225.1 - 1.5e-21 76.5 0.2 3.9e-21 75.1 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 GBG87225.1 - 1.1e-16 61.1 1.2 4.2e-16 59.2 1.2 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 LCAT PF02450.15 GBG87226.1 - 0.0076 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase BRE1 PF08647.11 GBG87227.1 - 0.0011 19.0 11.8 0.0011 19.0 11.8 10.2 4 2 6 10 10 10 5 BRE1 E3 ubiquitin ligase MeaB PF03308.16 GBG87229.1 - 0.00026 20.0 1.0 0.0056 15.7 0.4 2.2 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 GBG87229.1 - 0.076 12.6 0.1 0.62 9.6 0.1 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NOP19 PF10863.8 GBG87229.1 - 0.13 12.1 5.8 0.56 10.0 0.1 3.0 3 1 1 4 4 4 0 Nucleolar protein 19 DUF1670 PF07900.11 GBG87229.1 - 0.25 10.7 2.3 7.4 5.8 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1670) DUF3953 PF13129.6 GBG87229.1 - 0.44 10.3 5.3 2.4 8.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) Ank_2 PF12796.7 GBG87230.1 - 4.3e-08 33.6 0.1 9.7e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG87230.1 - 1.2e-06 28.9 0.2 1.8e-05 25.2 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG87230.1 - 1.8e-05 24.7 0.1 0.013 15.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GBG87230.1 - 0.009 16.4 0.2 0.77 10.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 GBG87230.1 - 0.12 12.8 0.1 1 9.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Metallophos PF00149.28 GBG87231.1 - 1.1e-32 114.3 0.1 1.8e-32 113.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_3 PF13415.6 GBG87231.1 - 7.7e-20 70.7 23.8 0.00013 22.2 1.7 8.2 8 1 0 8 8 8 6 Galactose oxidase, central domain Kelch_4 PF13418.6 GBG87231.1 - 5.8e-18 64.6 9.7 5.6e-05 23.1 0.0 6.4 4 2 1 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 GBG87231.1 - 1.4e-16 59.7 2.8 0.00097 19.0 0.0 6.5 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 GBG87231.1 - 3.5e-16 58.8 8.9 0.00039 20.3 0.0 6.8 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.25 GBG87231.1 - 2.4e-13 49.4 5.8 0.004 16.7 0.5 6.5 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GBG87231.1 - 6.4e-13 48.5 1.4 0.026 14.8 0.0 6.6 6 1 0 6 6 6 3 Kelch motif STPPase_N PF16891.5 GBG87231.1 - 0.00018 21.9 0.1 0.00031 21.1 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Integrase_H2C2 PF17921.1 GBG87233.1 - 2.1e-17 63.0 3.2 2.1e-17 62.9 1.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG87233.1 - 9.7e-09 35.4 0.0 5e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG87233.1 - 1.7e-05 24.6 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG87233.1 - 6.1e-05 23.5 0.0 0.00019 21.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87233.1 - 0.00059 20.4 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG87233.1 - 0.00071 19.8 6.5 0.0036 17.5 0.0 3.9 4 0 0 4 4 4 1 Retrotransposon gag protein Chromo PF00385.24 GBG87233.1 - 0.018 14.9 1.3 0.02 14.8 0.1 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG87233.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG87234.1 - 1.7e-20 73.2 0.0 3.9e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87234.1 - 3.8e-19 68.6 0.0 9.6e-19 67.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87234.1 - 1.1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG87234.1 - 0.003 18.1 0.0 0.007 16.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87234.1 - 0.0089 16.7 0.0 0.02 15.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG87235.1 - 3.1e-27 95.6 0.0 2.2e-26 92.8 0.0 2.2 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87235.1 - 2e-08 34.2 0.0 5.7e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG87235.1 - 3.1e-05 24.2 3.3 0.00064 19.9 0.1 3.8 4 0 0 4 4 4 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG87235.1 - 0.0054 17.3 4.9 0.012 16.3 2.2 2.4 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4618 PF15397.6 GBG87235.1 - 0.03 13.8 0.1 0.055 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF72 PF01904.18 GBG87235.1 - 0.094 12.8 1.0 0.21 11.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF72 BLOC1_2 PF10046.9 GBG87235.1 - 0.13 12.5 3.0 2.9 8.2 1.1 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GBG87235.1 - 0.14 12.7 1.0 1.3 9.5 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.8 GBG87235.1 - 0.15 12.1 3.2 0.41 10.7 1.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding LPP PF04728.13 GBG87235.1 - 1.7 9.1 4.1 10 6.6 0.1 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DivIC PF04977.15 GBG87235.1 - 1.9 8.3 4.9 6.1 6.7 2.3 2.3 2 0 0 2 2 2 0 Septum formation initiator CLZ PF16526.5 GBG87235.1 - 4.8 7.6 8.2 10 6.5 2.0 3.3 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2457 PF10446.9 GBG87236.1 - 0.096 11.8 25.1 0.13 11.4 25.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF659 PF04937.15 GBG87237.1 - 1.5e-39 135.3 0.0 3.1e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87237.1 - 1.9e-06 27.6 0.9 1.9e-05 24.3 0.9 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG87237.1 - 0.0078 16.0 1.1 0.0078 16.0 1.1 2.9 2 0 0 2 2 2 1 AT hook motif zf-BED PF02892.15 GBG87237.1 - 0.077 13.0 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 BED zinc finger Pox_Ag35 PF03286.14 GBG87237.1 - 0.093 12.5 2.2 0.19 11.5 2.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GNAT_acetyltr_2 PF13718.6 GBG87241.1 - 6.7e-99 329.9 0.0 1.1e-98 329.2 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 GBG87241.1 - 4.5e-64 215.5 0.0 1.3e-63 214.0 0.0 1.8 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.6 GBG87241.1 - 6.2e-43 147.2 2.0 7.7e-43 146.9 0.0 2.0 2 0 0 2 2 2 1 Possible tRNA binding domain DUF1726 PF08351.11 GBG87241.1 - 2.8e-32 110.5 0.0 8.5e-32 109.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 GBG87241.1 - 0.00062 19.5 0.0 0.082 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran_2 PF16949.5 GBG87241.1 - 0.089 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-binding cassette DEAD PF00270.29 GBG87241.1 - 0.15 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase RVT_1 PF00078.27 GBG87242.1 - 2.6e-26 92.5 0.1 4.1e-26 91.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87242.1 - 3e-13 49.7 1.0 1.1e-05 25.4 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87242.1 - 1.6e-12 47.7 0.9 4.2e-12 46.3 0.9 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87242.1 - 3e-10 40.0 0.0 7.8e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain NAC PF01849.18 GBG87243.1 - 8.6e-23 80.1 0.1 1.7e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 NAC domain DUF659 PF04937.15 GBG87244.1 - 4.4e-32 111.1 0.0 7.1e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87244.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG87245.1 - 3e-28 97.8 0.0 5.3e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87245.1 - 1.3e-26 92.9 0.0 2.2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87245.1 - 5.8e-10 39.1 0.1 8e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG87245.1 - 0.89 7.7 26.5 1.3 7.2 26.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG87245.1 - 2.3 7.5 30.7 3.4 6.9 30.7 1.1 1 0 0 1 1 1 0 BUD22 DUF659 PF04937.15 GBG87246.1 - 9.9e-30 103.4 0.0 2.5e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) WD40 PF00400.32 GBG87246.1 - 1.3e-17 63.9 5.4 0.002 18.9 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG87246.1 - 2e-15 56.9 0.2 0.0001 22.6 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain zf-BED PF02892.15 GBG87246.1 - 4.5e-06 26.6 6.2 0.027 14.5 0.1 2.8 2 0 0 2 2 2 2 BED zinc finger Dimer_Tnp_hAT PF05699.14 GBG87246.1 - 0.0019 17.9 0.1 0.0043 16.8 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PyrI_C PF02748.15 GBG87246.1 - 6.6 6.7 5.4 1.9 8.4 0.2 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Piezo_RRas_bdg PF12166.8 GBG87247.1 - 9.5e-90 301.9 0.0 2.2e-89 300.7 0.0 1.6 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain RT_RNaseH_2 PF17919.1 GBG87247.1 - 4.5e-33 113.3 0.0 9.8e-33 112.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87247.1 - 9.6e-30 103.0 0.0 2e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87247.1 - 6.5e-18 64.6 0.1 1.7e-17 63.2 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain NVEALA PF14055.6 GBG87247.1 - 0.15 12.1 0.2 0.43 10.6 0.2 1.8 1 0 0 1 1 1 0 NVEALA protein Rx_N PF18052.1 GBG87247.1 - 0.94 9.8 3.7 3 8.2 3.7 1.8 1 0 0 1 1 1 0 Rx N-terminal domain NOA36 PF06524.12 GBG87248.1 - 9.3 5.5 12.4 19 4.4 12.4 1.4 1 0 0 1 1 1 0 NOA36 protein Integrase_H2C2 PF17921.1 GBG87249.1 - 1.4e-15 57.2 0.0 2.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87249.1 - 9.4e-14 51.6 0.0 1.8e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF3493 PF11998.8 GBG87252.1 - 1.7e-23 82.6 0.1 3.2e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 TPR_1 PF00515.28 GBG87252.1 - 8.1e-06 25.4 0.5 0.023 14.5 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG87252.1 - 2.4e-05 24.9 1.2 2.4e-05 24.9 1.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG87252.1 - 0.0011 18.9 7.6 0.035 14.2 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GBG87252.1 - 0.025 14.7 0.5 0.29 11.3 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG87252.1 - 0.029 15.0 0.4 0.52 11.1 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG87252.1 - 0.11 12.8 0.3 18 5.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Biotin_lipoyl_2 PF13533.6 GBG87253.1 - 0.15 11.9 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like Biotin_lipoyl PF00364.22 GBG87255.1 - 0.00011 22.0 0.3 0.00024 20.8 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme RT_RNaseH_2 PF17919.1 GBG87256.1 - 2.3e-32 111.0 0.0 6.4e-32 109.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87256.1 - 1.1e-30 106.0 0.6 3.1e-30 104.5 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87256.1 - 1.9e-18 66.3 0.7 4e-18 65.3 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG87256.1 - 0.002 18.3 0.1 0.0074 16.5 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG87256.1 - 0.11 12.0 0.1 0.11 12.0 0.1 3.3 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG87257.1 - 2.6e-38 131.8 0.0 5.1e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG87258.1 - 1.2e-14 54.5 0.0 2.3e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG87258.1 - 1.4e-09 37.9 0.0 2.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rotamase_2 PF13145.6 GBG87258.1 - 0.031 15.1 0.3 0.073 13.9 0.1 1.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain DAG_kinase_N PF14513.6 GBG87258.1 - 0.29 11.3 0.8 0.55 10.4 0.8 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Rrn6 PF10214.9 GBG87258.1 - 3 6.2 7.6 4.3 5.7 7.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor gag-asp_proteas PF13975.6 GBG87260.1 - 1.1e-06 29.2 0.1 4.1e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87260.1 - 0.00017 22.1 0.0 0.00047 20.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87260.1 - 0.0091 15.8 0.4 0.018 14.9 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG87260.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG87261.1 - 0.0001 22.5 11.2 0.0027 18.0 0.1 4.5 4 2 1 5 5 5 2 Retrotransposon gag protein CLZ PF16526.5 GBG87261.1 - 0.018 15.4 3.6 0.072 13.5 0.4 3.3 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RT_RNaseH PF17917.1 GBG87262.1 - 1.1e-25 90.0 0.1 3e-25 88.5 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87262.1 - 4e-25 87.8 0.0 1.3e-24 86.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87262.1 - 7.7e-16 58.3 0.1 1.5e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG87262.1 - 0.065 12.9 0.1 0.065 12.9 0.1 2.7 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH PF17917.1 GBG87263.1 - 1.9e-74 246.7 4.1 5.8e-29 100.5 0.1 4.7 3 1 1 4 4 4 4 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87263.1 - 9.9e-72 237.3 0.2 3.3e-32 110.5 0.0 4.7 3 1 1 4 4 4 4 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87263.1 - 1.4e-17 63.9 0.0 3.5e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87263.1 - 8.3e-17 61.0 0.2 1.9e-16 59.9 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87263.1 - 2.7e-05 24.4 0.0 0.00015 22.0 0.0 2.3 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG87263.1 - 0.0076 16.5 0.7 0.11 12.8 0.2 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein Mcp5_PH PF12814.7 GBG87263.1 - 0.02 15.0 4.2 2.8 8.1 0.3 2.6 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology NAAA-beta PF15508.6 GBG87263.1 - 0.1 13.0 0.2 27 5.2 0.0 3.0 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CLZ PF16526.5 GBG87263.1 - 0.31 11.4 5.4 2.9 8.3 0.3 4.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tropomyosin_1 PF12718.7 GBG87263.1 - 1.6 8.8 7.2 24 5.0 0.2 3.6 3 1 0 3 3 3 0 Tropomyosin like RT_RNaseH_2 PF17919.1 GBG87264.1 - 2.1e-32 111.1 0.0 6.5e-32 109.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87264.1 - 1.2e-30 105.9 0.0 3.6e-30 104.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87264.1 - 1.1e-13 51.0 0.1 3.2e-13 49.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG87264.1 - 5e-09 36.0 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG87264.1 - 0.055 13.1 0.0 0.055 13.1 0.0 3.3 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase LAP1C PF05609.12 GBG87264.1 - 0.74 8.8 25.7 1.1 8.2 25.7 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Myco_haema PF05692.12 GBG87264.1 - 3.8 6.4 10.1 0.12 11.4 3.9 1.5 2 0 0 2 2 2 0 Mycoplasma haemagglutinin DNA_pol_phi PF04931.13 GBG87264.1 - 4.2 5.4 30.2 6.7 4.7 30.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 GBG87264.1 - 8.6 5.5 13.4 16 4.6 13.4 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 GBG87264.1 - 9.6 5.4 17.6 20 4.4 17.6 1.5 1 0 0 1 1 1 0 NOA36 protein RT_RNaseH_2 PF17919.1 GBG87265.1 - 6.4e-32 109.6 0.1 1.7e-31 108.2 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87265.1 - 5.1e-31 107.9 0.1 1.4e-30 106.4 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87265.1 - 6.7e-28 97.1 0.1 1.8e-27 95.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87265.1 - 1.6e-18 66.5 0.1 3.3e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87265.1 - 1.2e-14 54.5 0.0 4.7e-14 52.6 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG87265.1 - 6.7e-07 29.5 1.6 0.0099 16.1 0.0 3.6 3 0 0 3 3 3 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG87265.1 - 0.08 13.2 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG87266.1 - 2.7e-27 95.7 0.0 4.6e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87266.1 - 1.3e-24 86.1 0.0 3.3e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87266.1 - 2.9e-23 82.1 0.0 5.8e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG87266.1 - 1.6e-07 31.9 0.0 3.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87266.1 - 8.6e-07 29.4 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87266.1 - 3.2e-06 27.0 0.0 6.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87266.1 - 0.00023 20.9 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87267.1 - 6.5e-07 29.2 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87267.1 - 0.00026 21.6 0.0 0.00067 20.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG87267.1 - 0.00027 21.1 0.1 0.0007 19.8 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG87267.1 - 0.022 15.3 0.0 0.07 13.7 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG87268.1 - 1.1e-33 116.6 0.0 2.7e-33 115.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87268.1 - 1.8e-18 66.4 0.0 4.1e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87268.1 - 4.4e-05 23.7 0.0 9.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87268.1 - 0.00032 20.9 0.0 0.00083 19.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain MSP1_C PF07462.11 GBG87268.1 - 0.36 9.5 2.1 0.26 10.0 0.2 1.6 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus RT_RNaseH PF17917.1 GBG87269.1 - 1.7e-13 50.7 0.0 2.4e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87269.1 - 1.8e-10 40.7 0.0 4.5e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG87269.1 - 0.00054 20.6 0.0 0.0018 18.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87269.1 - 0.0017 18.9 0.0 0.0053 17.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87269.1 - 0.0021 17.8 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Ribonuc_2-5A PF06479.12 GBG87269.1 - 0.033 14.4 0.1 0.089 13.0 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease 2-5A Retrotrans_gag PF03732.17 GBG87269.1 - 0.23 11.7 3.4 8.7 6.7 0.1 3.6 3 0 0 3 3 3 0 Retrotransposon gag protein tRNA-synt_His PF13393.6 GBG87270.1 - 2.9e-43 148.3 0.0 5.4e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 GBG87270.1 - 4.3e-10 39.6 0.5 9.3e-10 38.5 0.5 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GBG87270.1 - 2.9e-09 37.2 0.0 8e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 GBG87270.1 - 0.05 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) HGTP_anticodon2 PF12745.7 GBG87270.1 - 0.074 12.5 1.6 0.13 11.7 1.6 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs MULE PF10551.9 GBG87271.1 - 1.9e-20 73.1 0.0 3.3e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG87271.1 - 3.7e-16 58.9 0.3 7.7e-16 57.8 0.3 1.5 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.18 GBG87271.1 - 2.1e-08 33.4 0.0 3.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family RT_RNaseH_2 PF17919.1 GBG87272.1 - 4.2e-06 26.7 0.0 2.5e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87272.1 - 0.00015 22.0 0.0 0.0045 17.3 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Jnk-SapK_ap_N PF09744.9 GBG87272.1 - 0.003 17.8 4.4 0.003 17.8 4.4 3.1 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 GBG87272.1 - 3.9 7.5 17.6 0.039 14.0 9.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein YbgS PF13985.6 GBG87273.1 - 0.2 12.0 1.1 0.45 10.8 0.8 1.7 2 0 0 2 2 2 0 YbgS-like protein PKcGMP_CC PF16808.5 GBG87273.1 - 4.8 7.1 6.3 20 5.2 1.6 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Prominin PF05478.11 GBG87274.1 - 1.5 6.7 4.3 3.2 5.6 3.4 1.8 1 1 1 2 2 2 0 Prominin Pkinase PF00069.25 GBG87275.1 - 2e-18 66.7 0.0 2.5e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG87275.1 - 9.7e-15 54.5 0.0 1.2e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG87275.1 - 0.0068 16.4 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG87275.1 - 0.013 14.4 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase LpoB PF13036.6 GBG87275.1 - 0.19 11.7 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB zf-RING_13 PF17977.1 GBG87278.1 - 0.082 13.1 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase_Tyr PF07714.17 GBG87280.1 - 1.3e-37 129.5 0.0 7.9e-37 126.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87280.1 - 1.2e-34 119.9 0.0 6.2e-34 117.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG87280.1 - 0.0079 16.1 0.0 0.018 14.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family LapA_dom PF06305.11 GBG87280.1 - 0.012 15.4 0.1 0.031 14.1 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TraG-D_C PF12696.7 GBG87281.1 - 0.38 10.7 0.1 0.38 10.7 0.1 3.3 3 1 0 3 3 3 0 TraM recognition site of TraD and TraG Pkinase_Tyr PF07714.17 GBG87282.1 - 1.1e-38 133.1 0.0 5.7e-38 130.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87282.1 - 8e-35 120.5 0.0 5.7e-34 117.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG87282.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 GBG87283.1 - 9.6e-27 93.0 0.0 1.8e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87283.1 - 6.6e-24 84.2 0.0 1.2e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87283.1 - 7.4e-18 64.4 0.5 2.9e-17 62.5 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG87283.1 - 6.9e-10 39.2 0.0 1.6e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG87283.1 - 0.084 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG87283.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG87284.1 - 0.0019 18.4 0.1 0.0052 17.0 0.1 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein Pkinase_Tyr PF07714.17 GBG87285.1 - 4.3e-38 131.1 0.0 1.8e-37 129.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87285.1 - 8.1e-33 113.9 0.0 1.4e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG87285.1 - 0.011 15.6 0.0 0.027 14.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG87285.1 - 0.083 11.6 0.0 0.16 10.7 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Rax2 PF12768.7 GBG87285.1 - 0.2 11.1 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity JmjC PF02373.22 GBG87286.1 - 0.0088 16.5 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Fes1 PF08609.10 GBG87286.1 - 2.6 9.0 7.5 8.5 7.3 7.5 1.9 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 OSCP PF00213.18 GBG87286.1 - 4.7 7.3 11.7 2.5 8.2 8.5 2.1 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit SpoIIIAH PF12685.7 GBG87286.1 - 7.3 6.4 18.1 8.3e+02 -0.4 18.1 2.4 1 1 0 1 1 1 0 SpoIIIAH-like protein Retrotrans_gag PF03732.17 GBG87287.1 - 8.3e-06 26.0 0.7 1.5e-05 25.1 0.2 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Pkinase PF00069.25 GBG87288.1 - 8.6e-27 94.1 0.0 1.2e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG87288.1 - 3.7e-26 91.9 0.0 5.9e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PRIMA1 PF16101.5 GBG87288.1 - 0.031 14.3 0.3 0.067 13.2 0.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3519 PF12033.8 GBG87288.1 - 0.28 11.6 2.9 0.62 10.5 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) RVT_1 PF00078.27 GBG87289.1 - 3.7e-25 88.8 0.1 7.4e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87289.1 - 2.1e-19 69.4 0.0 6.5e-19 67.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87289.1 - 4.8e-09 36.5 0.0 1.2e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG87289.1 - 8.8e-08 32.7 0.0 2.5e-07 31.2 0.0 1.8 2 0 0 2 2 1 1 Aspartyl protease rve PF00665.26 GBG87289.1 - 9.6e-08 32.2 0.1 5.8e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG87289.1 - 2.6e-07 30.5 0.0 7.4e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG87289.1 - 1.2e-06 28.5 1.6 2.5e-06 27.5 1.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG87289.1 - 9.3e-06 26.1 0.0 2.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG87289.1 - 0.0013 19.0 0.7 0.0082 16.4 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein APG17 PF04108.12 GBG87289.1 - 0.0048 16.1 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 Asp_protease PF09668.10 GBG87289.1 - 0.2 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Pkinase_Tyr PF07714.17 GBG87294.1 - 1.8e-37 129.0 0.0 2.9e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87294.1 - 2.2e-34 119.0 0.0 8.7e-34 117.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG87294.1 - 0.00015 21.8 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PRIMA1 PF16101.5 GBG87294.1 - 0.46 10.5 2.5 1.1 9.3 2.5 1.6 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 RVT_1 PF00078.27 GBG87296.1 - 1.2e-10 41.3 0.0 1.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 GBG87297.1 - 5.6e-38 130.7 0.0 9.4e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87297.1 - 1.9e-37 129.1 0.0 3.3e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Retrotrans_gag PF03732.17 GBG87297.1 - 0.0011 19.1 0.1 0.0039 17.4 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Alpha_GJ PF03229.13 GBG87297.1 - 0.0026 18.3 0.1 0.008 16.7 0.1 1.9 1 0 0 1 1 1 1 Alphavirus glycoprotein J Pkinase_fungal PF17667.1 GBG87297.1 - 0.0066 15.3 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase zf-C2H2_jaz PF12171.8 GBG87298.1 - 0.049 13.9 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AbbA_antirepres PF14156.6 GBG87299.1 - 0.17 11.8 0.1 0.44 10.5 0.1 1.6 1 0 0 1 1 1 0 Antirepressor AbbA Pkinase_Tyr PF07714.17 GBG87300.1 - 8.1e-38 130.2 0.0 2.1e-37 128.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87300.1 - 1.8e-36 125.9 0.0 3.6e-36 124.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG87300.1 - 0.029 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase XylR_N PF06505.11 GBG87300.1 - 0.052 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Activator of aromatic catabolism Endothelin PF00322.17 GBG87300.1 - 0.49 10.0 6.9 12 5.6 1.0 3.4 1 1 1 3 3 3 0 Endothelin family Pkinase PF00069.25 GBG87301.1 - 3.1e-25 89.0 0.1 8.1e-19 68.0 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG87301.1 - 2.3e-20 73.0 0.0 2.2e-14 53.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG87301.1 - 0.0005 19.0 0.0 0.00093 18.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG87301.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Histone PF00125.24 GBG87302.1 - 1.6e-21 77.0 2.4 2.1e-21 76.7 2.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG87302.1 - 3.2e-05 24.1 0.1 3.2e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GBG87302.1 - 0.0012 19.3 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 GBG87302.1 - 0.0037 17.3 2.8 0.0045 17.1 2.8 1.1 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 GBG87302.1 - 0.013 15.1 0.2 1.8 8.2 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Hydant_A_N PF05378.13 GBG87302.1 - 0.054 13.2 0.2 0.078 12.7 0.2 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Hat1_N PF10394.9 GBG87303.1 - 1.4e-29 103.4 0.0 4.6e-29 101.7 0.0 1.9 1 1 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 GBG87303.1 - 8.9e-06 25.9 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GBG87303.1 - 0.00015 22.2 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GBG87303.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 GBG87303.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Na_trans_assoc PF06512.13 GBG87304.1 - 0.001 19.4 2.7 0.0016 18.7 2.7 1.4 1 0 0 1 1 1 1 Sodium ion transport-associated BUD22 PF09073.10 GBG87304.1 - 0.016 14.6 18.9 0.026 13.9 18.9 1.2 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 GBG87304.1 - 0.017 14.9 9.9 0.052 13.3 9.9 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 GBG87304.1 - 0.52 11.0 20.1 0.043 14.5 14.2 2.3 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) SAPS PF04499.15 GBG87304.1 - 1.1 8.0 3.5 1.7 7.4 3.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 GBG87304.1 - 1.7 8.0 21.4 2.9 7.2 21.4 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG87304.1 - 2.1 6.5 18.0 3.2 5.9 18.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG87304.1 - 2.7 6.1 21.9 0.24 9.6 17.3 1.5 2 0 0 2 2 2 0 Nop14-like family NPR3 PF03666.13 GBG87304.1 - 2.7 6.7 8.5 5.5 5.7 8.5 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Plasmodium_Vir PF05795.11 GBG87304.1 - 2.7 7.3 5.6 4.4 6.6 5.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RR_TM4-6 PF06459.12 GBG87304.1 - 2.9 7.6 11.6 6.5 6.5 11.6 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 GBG87304.1 - 4.1 6.3 22.0 8.6 5.2 22.0 1.5 1 0 0 1 1 1 0 Paf1 SGL PF08450.12 GBG87305.1 - 0.0059 16.2 0.0 0.095 12.3 0.0 2.5 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region DUF3138 PF11336.8 GBG87306.1 - 0.52 8.9 2.4 0.86 8.1 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Herpes_UL25 PF01499.16 GBG87306.1 - 7.1 5.0 8.3 56 2.1 7.7 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family RT_RNaseH PF17917.1 GBG87307.1 - 2.1e-20 73.0 0.0 4.2e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87307.1 - 1.5e-13 50.6 0.0 3.6e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG87307.1 - 1.2e-10 41.3 0.0 3e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG87307.1 - 0.00017 21.8 0.0 0.00036 20.7 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG87307.1 - 0.0089 16.2 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain SGL PF08450.12 GBG87307.1 - 0.074 12.6 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Hydrolase_4 PF12146.8 GBG87308.1 - 4.6e-14 52.3 0.0 2.5e-08 33.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GBG87308.1 - 6.2e-08 32.4 0.0 1.4e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GBG87308.1 - 4.3e-07 29.8 0.0 0.0069 16.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 GBG87308.1 - 7.4e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 GBG87308.1 - 3.2e-05 23.7 0.0 7.8e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 GBG87308.1 - 0.0009 19.2 0.0 1.6 8.6 0.0 2.3 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 GBG87308.1 - 0.0092 15.8 0.1 0.055 13.3 0.1 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF818 PF05677.12 GBG87308.1 - 0.026 13.5 0.2 0.047 12.6 0.2 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 GBG87308.1 - 0.085 13.4 0.0 0.3 11.6 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 GBG87308.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 GBG87308.1 - 0.16 10.7 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Pkinase PF00069.25 GBG87309.1 - 2.4e-63 214.0 0.0 3.2e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG87309.1 - 1.4e-38 132.7 0.0 1.8e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG87309.1 - 0.00032 20.1 0.0 0.0051 16.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 GBG87309.1 - 0.057 13.0 0.3 6.8 6.2 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 GBG87309.1 - 0.11 11.3 0.1 0.15 10.8 0.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 GBG87309.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RT_RNaseH PF17917.1 GBG87311.1 - 4.5e-29 100.8 0.0 1.1e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87311.1 - 1.6e-28 98.6 0.0 1e-12 48.0 0.0 2.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87311.1 - 7.5e-14 51.6 2.0 7.7e-14 51.5 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG87311.1 - 7.5e-11 42.3 0.1 3.1e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG87311.1 - 6.6e-06 25.8 0.0 2.5e-05 23.9 0.0 1.9 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG87311.1 - 0.00037 20.6 0.0 0.00092 19.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG87311.1 - 0.19 11.5 0.2 0.63 9.9 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like zf-DNL PF05180.12 GBG87312.1 - 6.2e-06 26.1 0.1 1.4e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 DNL zinc finger Ribosomal_60s PF00428.19 GBG87312.1 - 1 10.0 9.8 2.5 8.8 9.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DNA_pol_phi PF04931.13 GBG87312.1 - 1.4 6.9 4.1 1.8 6.5 4.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GBG87312.1 - 9.4 5.5 7.4 17 4.6 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein JAB PF01398.21 GBG87313.1 - 1.1e-13 51.2 0.0 2.1e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4191 PF13829.6 GBG87313.1 - 0.16 11.3 5.6 0.31 10.4 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Actin PF00022.19 GBG87314.1 - 5.1e-72 242.7 0.0 1.3e-69 234.8 0.0 2.4 1 1 0 1 1 1 1 Actin ANAPC9 PF12856.7 GBG87314.1 - 0.091 13.0 0.0 0.091 13.0 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 RXT2_N PF08595.11 GBG87314.1 - 0.18 11.8 4.2 0.055 13.5 1.4 1.5 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 GBG87314.1 - 5.8 6.1 21.2 10 5.3 21.2 1.3 1 0 0 1 1 1 0 NOA36 protein Actin PF00022.19 GBG87315.1 - 7e-26 90.8 0.0 8e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Actin ANAPC9 PF12856.7 GBG87315.1 - 0.0077 16.4 0.0 0.0086 16.3 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 9 Spermine_synth PF01564.17 GBG87316.1 - 9.7e-61 204.5 0.0 1.6e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 GBG87316.1 - 3.8e-23 81.1 0.1 7e-23 80.3 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GBG87316.1 - 2.8e-05 24.7 0.1 7.1e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG87316.1 - 0.016 16.0 0.0 0.034 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GBG87316.1 - 0.044 13.3 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF3808 PF10300.9 GBG87317.1 - 4.2e-43 147.8 0.0 1.2e-42 146.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) Integrase_H2C2 PF17921.1 GBG87317.1 - 8.2e-15 54.7 0.1 2.1e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG87317.1 - 9.8e-11 41.6 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG87317.1 - 1e-10 41.8 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG87317.1 - 1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87317.1 - 0.006 17.2 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87317.1 - 0.012 16.2 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease TPR_2 PF07719.17 GBG87317.1 - 0.024 14.7 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG87317.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG87317.1 - 0.12 12.6 0.1 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Na_Ca_ex PF01699.24 GBG87318.1 - 2.7e-42 144.3 49.8 2.8e-25 89.0 18.0 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF2157 PF09925.9 GBG87318.1 - 0.0025 17.6 1.6 0.038 13.8 0.3 3.2 2 2 0 2 2 2 1 Predicted membrane protein (DUF2157) YqzM PF14141.6 GBG87318.1 - 0.49 10.5 10.4 5 7.2 0.3 3.8 3 0 0 3 3 3 0 YqzM-like protein Myb_DNA-bind_4 PF13837.6 GBG87322.1 - 3e-09 37.1 0.1 5.3e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG87322.1 - 0.059 13.7 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 GBG87323.1 - 2e-08 34.5 2.1 4.5e-08 33.4 2.0 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG87323.1 - 0.05 13.7 1.5 0.12 12.5 1.5 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG87323.1 - 0.26 11.6 2.4 0.45 10.9 1.1 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CENP-Q PF13094.6 GBG87327.1 - 0.0013 18.9 4.7 0.0019 18.4 4.7 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Chordopox_A30L PF06015.12 GBG87327.1 - 0.085 12.7 0.3 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus A30L protein PAP_fibrillin PF04755.12 GBG87327.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 PAP_fibrillin Oscp1 PF10188.9 GBG87328.1 - 1.5e-61 207.6 0.5 1.9e-61 207.2 0.5 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 SRP54 PF00448.22 GBG87329.1 - 3.2e-68 229.2 0.0 4.5e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 GBG87329.1 - 7.2e-09 35.7 0.3 2e-08 34.3 0.3 1.9 1 1 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.6 GBG87329.1 - 0.0017 18.6 0.2 0.0078 16.5 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GBG87329.1 - 0.0017 18.8 0.2 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GBG87329.1 - 0.0036 17.0 0.4 0.0072 16.1 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG87329.1 - 0.013 15.9 0.4 0.042 14.2 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 GBG87329.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 GBG87329.1 - 0.03 14.2 1.2 1.8 8.5 1.4 2.5 2 0 0 2 2 2 0 NACHT domain CbiA PF01656.23 GBG87329.1 - 0.049 13.7 0.0 0.21 11.7 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 GBG87329.1 - 0.084 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_31 PF13614.6 GBG87329.1 - 0.12 12.3 0.8 0.19 11.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GBG87329.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AP_endonuc_2 PF01261.24 GBG87329.1 - 0.13 11.7 0.0 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel AAA_27 PF13514.6 GBG87329.1 - 0.13 11.8 0.5 0.81 9.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain MobB PF03205.14 GBG87329.1 - 0.18 11.7 0.6 0.5 10.3 0.6 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4709 PF15821.5 GBG87330.1 - 4.4e-08 33.4 4.1 8.8e-08 32.4 4.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4709) AA_kinase PF00696.28 GBG87331.1 - 1.2e-13 51.2 0.5 2.5e-13 50.2 0.5 1.4 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 GBG87331.1 - 2.3e-11 43.9 0.0 6.1e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GBG87331.1 - 9.4e-06 26.0 0.0 2.5e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GBG87331.1 - 4.8e-05 23.3 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GBG87331.1 - 0.0021 18.2 0.0 0.019 15.1 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Serglycin PF04360.12 GBG87331.1 - 0.031 14.2 0.3 0.031 14.2 0.3 2.6 2 0 0 2 2 2 0 Serglycin UbiA PF01040.18 GBG87332.1 - 5.6e-21 75.0 4.3 7.8e-21 74.5 4.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2878 PF11086.8 GBG87332.1 - 0.025 14.8 0.1 0.08 13.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2878) Methyltransf_25 PF13649.6 GBG87333.1 - 9.8e-20 71.1 0.1 2.3e-19 69.9 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG87333.1 - 1.1e-18 67.5 0.0 1.6e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GBG87333.1 - 6.4e-18 65.2 0.1 1.6e-17 64.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GBG87333.1 - 4.4e-16 59.0 0.0 7.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GBG87333.1 - 6.5e-12 46.1 0.1 2e-11 44.5 0.0 1.9 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG87333.1 - 3.6e-09 36.7 0.0 5.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GBG87333.1 - 7.8e-09 35.3 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 GBG87333.1 - 8.6e-07 28.9 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 GBG87333.1 - 4.7e-05 23.2 0.0 7.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 GBG87333.1 - 0.00024 20.6 0.0 0.00039 19.9 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 GBG87333.1 - 0.00035 20.4 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) UPF0020 PF01170.18 GBG87333.1 - 0.00046 19.9 0.1 0.0018 18.0 0.1 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 GBG87333.1 - 0.0016 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 GBG87333.1 - 0.01 15.1 0.1 0.033 13.5 0.1 1.8 1 1 0 1 1 1 0 O-methyltransferase domain PCMT PF01135.19 GBG87333.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TRM PF02005.16 GBG87333.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FmrO PF07091.11 GBG87333.1 - 0.036 13.6 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_20 PF12147.8 GBG87333.1 - 0.05 12.7 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_15 PF09445.10 GBG87333.1 - 0.07 12.7 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 GBG87333.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_18 PF12847.7 GBG87333.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain KdpC PF02669.15 GBG87333.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Methyltr_RsmB-F PF01189.17 GBG87333.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F zf-CCHC PF00098.23 GBG87334.1 - 1.3e-08 34.5 2.0 2.5e-08 33.6 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Fzo_mitofusin PF04799.13 GBG87334.1 - 0.28 10.7 7.6 0.24 11.0 0.7 3.1 2 1 1 3 3 3 0 fzo-like conserved region Spc7 PF08317.11 GBG87334.1 - 0.77 8.6 26.4 0.5 9.2 20.9 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 GBG87334.1 - 0.84 9.7 5.3 0.9 9.6 1.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CorA PF01544.18 GBG87334.1 - 1 8.6 8.1 0.04 13.2 1.2 2.0 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein ZapB PF06005.12 GBG87334.1 - 1.1 9.7 29.9 0.17 12.3 0.7 4.5 3 1 1 4 4 4 0 Cell division protein ZapB RRN3 PF05327.11 GBG87334.1 - 1.3 7.5 10.8 0.27 9.7 7.2 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CAP_N PF01213.19 GBG87334.1 - 3.7 7.0 15.6 1.5 8.3 0.7 2.6 2 1 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF1943 PF09172.11 GBG87334.1 - 5.2 6.2 7.2 8.9 5.4 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Integrase_H2C2 PF17921.1 GBG87336.1 - 4.8e-16 58.6 0.1 1e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87336.1 - 2e-05 24.8 0.0 6.3e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG87336.1 - 0.0078 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RsbU_N PF08673.10 GBG87337.1 - 0.016 15.3 0.5 0.027 14.6 0.5 1.3 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain P19Arf_N PF07392.12 GBG87338.1 - 0.015 15.8 0.3 0.075 13.5 0.3 2.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus DUF4149 PF13664.6 GBG87338.1 - 0.25 11.7 11.6 0.032 14.6 2.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) ELMO_CED12 PF04727.13 GBG87340.1 - 8.9e-50 169.2 0.0 1.1e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family Histone PF00125.24 GBG87341.1 - 2.1e-15 57.3 0.1 2.1e-15 57.3 0.1 2.5 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CDC45 PF02724.14 GBG87341.1 - 5.1 5.3 14.4 7.3 4.8 14.4 1.2 1 0 0 1 1 1 0 CDC45-like protein LRR_4 PF12799.7 GBG87342.1 - 3e-24 84.7 21.4 1.5e-06 28.4 1.1 6.5 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG87342.1 - 2.1e-19 69.0 42.0 1.4e-07 31.1 1.3 4.8 2 1 5 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 GBG87342.1 - 5.1e-17 61.9 4.0 3.5e-08 33.2 0.0 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 GBG87342.1 - 0.008 16.2 21.8 4.2 7.7 0.1 8.4 10 0 0 10 10 10 1 Leucine Rich repeat LRR_1 PF00560.33 GBG87342.1 - 0.41 11.4 15.7 30 5.7 0.1 7.6 7 2 0 7 7 7 0 Leucine Rich Repeat RNA_polI_A34 PF08208.11 GBG87342.1 - 4.4 7.3 18.7 7.7 6.6 18.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PRKCSH PF07915.13 GBG87343.1 - 1.6e-15 57.9 2.1 3.2e-15 56.9 2.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 GBG87343.1 - 7e-05 22.6 0.2 0.00026 20.7 0.2 1.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Flavin_Reduct PF01613.18 GBG87344.1 - 6.9e-16 58.7 0.0 1.4e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Flavin reductase like domain Flavodoxin_1 PF00258.25 GBG87344.1 - 1.8e-06 28.2 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 GBG87344.1 - 0.053 13.8 0.0 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain Spc24 PF08286.11 GBG87344.1 - 0.19 12.0 0.0 0.52 10.6 0.0 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 BUD22 PF09073.10 GBG87346.1 - 0.011 15.2 19.6 0.014 14.8 19.6 1.2 1 0 0 1 1 1 0 BUD22 DDHD PF02862.17 GBG87346.1 - 0.029 14.5 0.3 0.029 14.5 0.3 1.2 1 0 0 1 1 1 0 DDHD domain PTPRCAP PF15713.5 GBG87346.1 - 0.032 14.5 18.8 0.083 13.2 18.8 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Zip PF02535.22 GBG87346.1 - 0.054 12.7 6.0 0.062 12.5 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GBG87346.1 - 0.31 9.8 15.5 0.35 9.6 15.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG87346.1 - 0.42 8.9 19.1 0.53 8.5 19.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 GBG87346.1 - 1.2 7.6 9.9 1.3 7.5 9.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Sporozoite_P67 PF05642.11 GBG87346.1 - 3.7 5.5 18.7 4.9 5.1 18.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Raftlin PF15250.6 GBG87346.1 - 4.3 6.0 11.5 5.3 5.7 11.5 1.1 1 0 0 1 1 1 0 Raftlin Pox_Ag35 PF03286.14 GBG87346.1 - 5 6.9 28.4 7.9 6.2 28.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BORG_CEP PF14957.6 GBG87346.1 - 7 7.8 9.7 13 7.0 9.7 1.4 1 0 0 1 1 1 0 Cdc42 effector Strabismus PF06638.11 GBG87346.1 - 7.3 5.1 5.9 9.7 4.7 5.9 1.1 1 0 0 1 1 1 0 Strabismus protein Glyco_hydro_28 PF00295.17 GBG87347.1 - 4.6e-46 157.4 0.0 6.1e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 GBG87347.1 - 9.3e-13 48.5 1.5 1.3e-09 38.3 0.0 2.8 2 1 1 3 3 3 3 Pectate lyase superfamily protein Translin PF01997.16 GBG87348.1 - 1.7e-46 158.8 0.0 2.1e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Translin family DHNA PF04038.12 GBG87348.1 - 0.066 13.7 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Dihydroneopterin aldolase Myb_DNA-bind_4 PF13837.6 GBG87349.1 - 2.9e-07 30.8 0.4 1.2e-05 25.6 0.0 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG87349.1 - 0.028 14.7 0.3 0.1 12.9 0.1 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 GBG87351.1 - 1.1e-07 32.1 5.3 1.4e-07 31.7 3.4 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG87351.1 - 0.00037 20.8 2.3 0.0058 16.9 0.8 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG87351.1 - 0.19 11.8 1.8 0.36 10.9 1.8 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Formyl_trans_N PF00551.19 GBG87352.1 - 8.1e-49 165.8 3.9 1e-48 165.5 0.0 2.4 3 0 0 3 3 3 1 Formyl transferase Kazal_2 PF07648.15 GBG87352.1 - 0.0055 16.8 1.7 4.4 7.5 0.0 4.0 4 0 0 4 4 4 1 Kazal-type serine protease inhibitor domain ER_lumen_recept PF00810.18 GBG87353.1 - 1.3e-37 129.9 8.1 2.4e-37 129.0 8.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 GBG87353.1 - 0.01 15.6 0.3 6.5 6.6 0.1 2.7 2 0 0 2 2 2 0 PQ loop repeat RVP_2 PF08284.11 GBG87355.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG87355.1 - 0.026 14.2 0.1 0.045 13.4 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease_2 PF13650.6 GBG87355.1 - 0.03 15.0 0.1 0.13 13.0 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Asp_protease PF09668.10 GBG87355.1 - 0.044 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease BMC PF00936.19 GBG87355.1 - 0.076 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 BMC domain DUF2291 PF10054.9 GBG87355.1 - 0.2 11.4 1.1 0.32 10.7 0.1 1.7 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) DUF4407 PF14362.6 GBG87356.1 - 0.0017 17.8 6.2 0.0017 17.8 6.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) HsbA PF12296.8 GBG87356.1 - 0.0083 16.5 1.7 0.032 14.7 1.7 2.0 1 0 0 1 1 1 1 Hydrophobic surface binding protein A NPV_P10 PF05531.12 GBG87356.1 - 0.13 12.7 0.2 0.37 11.3 0.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pantoate_transf PF02548.15 GBG87357.1 - 1.2e-109 365.8 0.3 1.8e-109 365.1 0.3 1.3 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 GBG87357.1 - 0.00094 18.7 0.1 0.00094 18.7 0.1 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 GBG87357.1 - 0.036 13.9 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase Ribosomal_60s PF00428.19 GBG87357.1 - 3.1 8.4 8.8 8.6 7.0 8.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein CX9C PF16860.5 GBG87358.1 - 0.0076 16.2 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ThiF PF00899.21 GBG87359.1 - 7.5e-18 64.8 0.0 1.5e-08 34.3 0.0 2.3 2 1 0 2 2 2 2 ThiF family Peptidase_C65 PF10275.9 GBG87360.1 - 2.2e-40 138.6 0.0 3.5e-36 124.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain Retrotrans_gag PF03732.17 GBG87360.1 - 1.1e-05 25.6 0.7 0.0023 18.2 0.0 2.6 2 0 0 2 2 2 2 Retrotransposon gag protein Adaptin_binding PF10199.9 GBG87360.1 - 0.55 10.8 7.0 0.28 11.8 0.9 2.5 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RIX1 PF08167.12 GBG87361.1 - 1.4e-24 86.9 0.0 2.4e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis RT_RNaseH_2 PF17919.1 GBG87362.1 - 3.4e-21 75.1 0.0 5.4e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87362.1 - 7.4e-11 42.3 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG87362.1 - 0.0092 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4746 PF15928.5 GBG87362.1 - 0.015 14.7 7.7 0.019 14.4 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Gpr1_Fun34_YaaH PF01184.19 GBG87363.1 - 2.1e-50 171.2 17.4 2.9e-50 170.7 17.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SDA1 PF05285.12 GBG87363.1 - 9.3 5.6 10.3 16 4.8 10.3 1.3 1 0 0 1 1 1 0 SDA1 Sec1 PF00995.23 GBG87364.1 - 0.033 13.4 0.9 0.062 12.5 0.0 1.9 3 0 0 3 3 3 0 Sec1 family RVT_1 PF00078.27 GBG87364.1 - 0.034 13.7 0.1 0.22 11.0 0.1 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) MIF4G_like_2 PF09090.11 GBG87364.1 - 3.9 6.9 8.6 8.8 5.7 8.6 1.5 1 0 0 1 1 1 0 MIF4G like CEP63 PF17045.5 GBG87366.1 - 0.00022 21.2 17.3 0.002 18.1 6.7 2.4 1 1 2 3 3 3 2 Centrosomal protein of 63 kDa Fez1 PF06818.15 GBG87366.1 - 0.0021 18.5 10.0 0.003 18.1 10.0 1.2 1 0 0 1 1 1 1 Fez1 Golgin_A5 PF09787.9 GBG87366.1 - 0.0032 17.0 6.4 0.0062 16.1 6.4 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 5 CC2-LZ PF16516.5 GBG87366.1 - 0.0038 17.6 3.1 0.055 13.8 0.3 2.4 1 1 1 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Filament PF00038.21 GBG87366.1 - 0.0079 15.8 8.1 0.012 15.2 8.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein CALCOCO1 PF07888.11 GBG87366.1 - 0.0084 15.0 9.9 0.011 14.6 9.9 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like ZapB PF06005.12 GBG87366.1 - 0.017 15.5 14.0 0.28 11.6 7.8 2.9 1 1 1 2 2 2 0 Cell division protein ZapB DUF5082 PF16888.5 GBG87366.1 - 0.024 14.9 2.2 0.046 14.0 0.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 GBG87366.1 - 0.025 13.9 8.5 0.066 12.6 8.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMCO5 PF14992.6 GBG87366.1 - 0.04 13.5 1.8 0.055 13.0 1.8 1.1 1 0 0 1 1 1 0 TMCO5 family Mis12 PF05859.12 GBG87366.1 - 0.044 13.8 1.5 0.082 13.0 0.1 2.0 2 1 0 2 2 2 0 Mis12 protein DivIC PF04977.15 GBG87366.1 - 0.053 13.3 0.3 0.053 13.3 0.3 2.7 1 1 0 2 2 2 0 Septum formation initiator ATG16 PF08614.11 GBG87366.1 - 0.064 13.5 15.3 0.25 11.5 6.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Macoilin PF09726.9 GBG87366.1 - 0.069 11.7 2.5 0.084 11.4 2.5 1.1 1 0 0 1 1 1 0 Macoilin family Snapin_Pallidin PF14712.6 GBG87366.1 - 0.08 13.4 5.5 4.2 7.9 0.3 3.2 1 1 2 3 3 3 0 Snapin/Pallidin DUF4404 PF14357.6 GBG87366.1 - 0.093 13.4 7.3 1.9 9.2 0.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 GBG87366.1 - 0.095 12.7 0.6 0.73 9.9 0.3 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HigB-like_toxin PF05015.13 GBG87366.1 - 0.17 12.3 0.1 5.7 7.4 0.0 2.4 2 0 0 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB KASH_CCD PF14662.6 GBG87366.1 - 0.19 11.6 10.3 0.16 11.8 6.7 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 GBG87366.1 - 0.2 12.3 2.9 0.28 11.8 0.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 GBG87366.1 - 0.22 11.8 11.3 3 8.1 10.0 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 GBG87366.1 - 0.44 9.4 10.6 0.25 10.2 2.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 GBG87366.1 - 0.5 10.4 8.0 0.22 11.5 1.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Med21 PF11221.8 GBG87366.1 - 0.5 10.6 13.2 2.2 8.5 0.5 3.0 1 1 3 4 4 4 0 Subunit 21 of Mediator complex ERM PF00769.19 GBG87366.1 - 0.57 10.0 15.4 1.5 8.6 15.4 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 GBG87366.1 - 0.61 10.7 12.3 0.82 10.3 3.2 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 GBG87366.1 - 0.66 9.0 4.0 0.93 8.5 4.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 GBG87366.1 - 1.6 9.7 9.0 61 4.6 8.1 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF724 PF05266.14 GBG87366.1 - 2.4 8.0 6.6 1.1 9.1 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 GBG87366.1 - 3.2 8.3 15.7 0.69 10.4 2.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Tup_N PF08581.10 GBG87366.1 - 3.9 7.8 10.8 3.7 7.9 1.8 4.0 2 2 3 5 5 3 0 Tup N-terminal CENP-F_leu_zip PF10473.9 GBG87366.1 - 4 7.5 10.8 0.74 9.8 6.0 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1192 PF06698.11 GBG87366.1 - 4.8 7.3 14.9 13 5.9 0.2 5.2 2 1 5 7 7 6 0 Protein of unknown function (DUF1192) G-gamma PF00631.22 GBG87366.1 - 9.8 6.3 10.8 6.5 6.8 1.0 4.0 2 1 3 5 5 5 0 GGL domain CEP63 PF17045.5 GBG87367.1 - 0.00019 21.4 16.6 0.0016 18.4 6.0 2.5 1 1 2 3 3 3 2 Centrosomal protein of 63 kDa Fez1 PF06818.15 GBG87367.1 - 0.0013 19.2 9.1 0.0018 18.8 9.1 1.2 1 0 0 1 1 1 1 Fez1 Golgin_A5 PF09787.9 GBG87367.1 - 0.0029 17.1 6.0 0.0058 16.1 6.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 CC2-LZ PF16516.5 GBG87367.1 - 0.0034 17.7 2.8 0.12 12.7 0.3 2.4 1 1 1 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CALCOCO1 PF07888.11 GBG87367.1 - 0.0073 15.2 9.5 0.01 14.8 9.5 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like ZapB PF06005.12 GBG87367.1 - 0.018 15.5 14.0 0.29 11.6 7.7 2.9 1 1 1 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 GBG87367.1 - 0.027 13.8 7.9 0.058 12.7 7.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Filament PF00038.21 GBG87367.1 - 0.036 13.6 8.0 0.084 12.4 7.9 1.6 1 1 0 1 1 1 0 Intermediate filament protein DUF5082 PF16888.5 GBG87367.1 - 0.04 14.2 2.8 0.053 13.8 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) HigB-like_toxin PF05015.13 GBG87367.1 - 0.041 14.3 0.1 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB ATG16 PF08614.11 GBG87367.1 - 0.047 13.9 14.8 0.19 12.0 6.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mis12 PF05859.12 GBG87367.1 - 0.054 13.5 2.0 0.087 12.9 0.0 2.2 2 1 1 3 3 3 0 Mis12 protein DivIC PF04977.15 GBG87367.1 - 0.055 13.2 0.3 0.055 13.2 0.3 2.8 2 1 0 3 3 2 0 Septum formation initiator Macoilin PF09726.9 GBG87367.1 - 0.071 11.7 2.5 0.088 11.4 2.5 1.1 1 0 0 1 1 1 0 Macoilin family TMCO5 PF14992.6 GBG87367.1 - 0.086 12.4 3.0 0.12 12.0 3.0 1.1 1 0 0 1 1 1 0 TMCO5 family Snapin_Pallidin PF14712.6 GBG87367.1 - 0.098 13.1 5.8 0.74 10.3 0.5 3.3 1 1 3 4 4 4 0 Snapin/Pallidin DUF1664 PF07889.12 GBG87367.1 - 0.11 12.6 0.7 0.96 9.5 0.1 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4404 PF14357.6 GBG87367.1 - 0.11 13.1 7.4 2.1 9.0 0.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) YabA PF06156.13 GBG87367.1 - 0.18 12.5 2.8 0.28 11.9 0.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 GBG87367.1 - 0.24 11.6 11.4 0.64 10.3 6.5 2.6 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 GBG87367.1 - 0.27 10.1 9.4 1.4 7.8 2.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein KASH_CCD PF14662.6 GBG87367.1 - 0.39 10.5 9.2 0.32 10.8 5.7 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HIP1_clath_bdg PF16515.5 GBG87367.1 - 0.48 11.1 11.5 0.82 10.3 3.1 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ERM PF00769.19 GBG87367.1 - 0.52 10.1 15.2 0.97 9.2 14.6 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Med21 PF11221.8 GBG87367.1 - 0.55 10.5 13.2 2.3 8.5 0.5 3.0 1 1 3 4 4 4 0 Subunit 21 of Mediator complex TMF_DNA_bd PF12329.8 GBG87367.1 - 0.56 10.2 8.0 0.2 11.7 1.5 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.6 GBG87367.1 - 0.88 8.9 5.9 5.9 6.2 4.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 GBG87367.1 - 1 8.4 4.5 1.4 7.9 4.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 GBG87367.1 - 1.3 9.1 10.7 0.4 10.7 6.8 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 GBG87367.1 - 2 8.2 6.5 1.2 8.9 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 GBG87367.1 - 2.1 9.3 9.2 69 4.4 8.3 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain SPATA1_C PF15743.5 GBG87367.1 - 2.5 8.2 8.5 5.7 7.0 2.3 2.6 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus APG6_N PF17675.1 GBG87367.1 - 2.7 8.5 14.1 28 5.2 13.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1192 PF06698.11 GBG87367.1 - 2.7 8.1 13.6 14 5.9 0.3 5.0 2 1 4 6 6 6 0 Protein of unknown function (DUF1192) Tup_N PF08581.10 GBG87367.1 - 2.8 8.3 10.0 3.2 8.1 0.2 4.0 2 2 2 4 4 4 0 Tup N-terminal DUF4200 PF13863.6 GBG87367.1 - 3.4 8.1 7.5 1.4e+02 2.9 1.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) G-gamma PF00631.22 GBG87367.1 - 9.8 6.3 10.6 6.7 6.8 1.0 4.0 2 1 3 5 5 5 0 GGL domain zf-CCHC PF00098.23 GBG87368.1 - 0.013 15.6 2.6 0.02 15.0 2.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Shugoshin_N PF07558.11 GBG87368.1 - 0.03 14.2 0.7 0.03 14.2 0.7 3.6 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Ku_PK_bind PF08785.11 GBG87368.1 - 0.2 11.8 0.2 0.2 11.8 0.2 2.6 2 1 0 2 2 2 0 Ku C terminal domain like Trypan_glycop PF00913.19 GBG87368.1 - 1 8.6 13.6 0.57 9.4 8.3 2.0 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) Gcd10p PF04189.13 GBG87373.1 - 6.3e-60 202.8 0.0 9.1e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family RT_RNaseH_2 PF17919.1 GBG87374.1 - 4.5e-31 106.8 0.1 7.5e-31 106.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87374.1 - 6e-28 97.9 0.1 8.2e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87374.1 - 5.6e-23 81.2 0.0 9.7e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DNA_ligase_A_M PF01068.21 GBG87375.1 - 3.2e-62 209.8 0.1 5e-62 209.2 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GBG87375.1 - 4.9e-40 137.7 0.0 8.4e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GBG87375.1 - 4.2e-24 85.0 0.0 2.3e-23 82.7 0.0 2.3 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 GBG87375.1 - 0.035 14.1 4.6 1.4 9.0 0.0 3.3 3 0 0 3 3 3 0 DNA ligase OB-like domain RMI1_N PF08585.12 GBG87377.1 - 9.8e-36 123.5 0.0 7.5e-34 117.4 0.0 2.2 1 1 0 1 1 1 1 RecQ mediated genome instability protein RMI1_C PF16099.5 GBG87377.1 - 8.2e-15 54.9 0.0 1.2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold RMI1_N PF08585.12 GBG87378.1 - 6.6e-36 124.1 0.0 6.5e-34 117.6 0.0 2.3 1 1 0 1 1 1 1 RecQ mediated genome instability protein RMI1_C PF16099.5 GBG87378.1 - 6.4e-15 55.2 0.0 9.5e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold RMI1_N PF08585.12 GBG87379.1 - 7.4e-36 123.9 0.0 6.9e-34 117.5 0.0 2.3 1 1 0 1 1 1 1 RecQ mediated genome instability protein RMI1_C PF16099.5 GBG87379.1 - 6.9e-15 55.1 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold RVT_1 PF00078.27 GBG87380.1 - 5e-16 58.9 0.0 2.1e-13 50.3 0.0 2.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD PF00628.29 GBG87380.1 - 8.1e-08 32.0 3.6 2e-07 30.8 3.6 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GBG87380.1 - 0.0014 18.1 0.8 0.0032 17.0 0.8 1.7 1 0 0 1 1 1 1 PHD-finger Cnd1_N PF12922.7 GBG87380.1 - 0.21 11.4 1.0 0.71 9.7 1.0 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term PTPA PF03095.15 GBG87382.1 - 7.5e-115 383.5 0.0 8.8e-115 383.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PBP1_TM PF14812.6 GBG87383.1 - 0.028 14.8 9.8 0.028 14.8 9.8 1.9 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.8 GBG87383.1 - 0.69 10.9 8.7 0.87 10.6 8.7 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4471 PF14740.6 GBG87384.1 - 1e-63 215.4 55.7 1.9e-59 201.4 0.1 4.6 3 1 0 3 3 3 2 Domain of unknown function (DUF4471) DUF4470 PF14737.6 GBG87384.1 - 1.5e-13 50.7 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) gag-asp_proteas PF13975.6 GBG87385.1 - 2e-06 28.2 0.2 5.4e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87385.1 - 4.3e-05 24.1 0.1 9.6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87385.1 - 0.0017 18.1 0.2 0.003 17.3 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG87385.1 - 0.047 13.3 0.3 0.047 13.3 0.3 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG87385.1 - 0.049 13.7 1.9 0.09 12.9 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG87386.1 - 5.2e-08 32.9 0.0 8.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Gas_vesicle_C PF01304.17 GBG87386.1 - 0.0032 17.4 8.4 0.64 10.1 0.4 3.6 3 0 0 3 3 3 2 Gas vesicles protein GVPc repeated domain Pterin_bind PF00809.22 GBG87386.1 - 0.0069 16.1 2.3 4.3 6.9 0.1 3.6 4 0 0 4 4 4 2 Pterin binding enzyme Anti-TRAP PF15777.5 GBG87386.1 - 0.02 14.9 0.2 8 6.5 0.0 3.2 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Pkinase_Tyr PF07714.17 GBG87387.1 - 1.1e-43 149.4 0.0 1.5e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87387.1 - 6.4e-43 147.0 0.0 8.6e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GBG87387.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF659 PF04937.15 GBG87388.1 - 2.7e-05 24.1 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87388.1 - 0.01 15.6 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region MTS PF05175.14 GBG87390.1 - 3.2e-07 30.0 0.1 3e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain DUF2457 PF10446.9 GBG87390.1 - 3.2e-05 23.3 17.3 5.7e-05 22.4 17.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.14 GBG87390.1 - 0.00011 20.7 14.5 0.00014 20.3 14.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Methyltransf_25 PF13649.6 GBG87390.1 - 0.00085 20.0 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Nop14 PF04147.12 GBG87390.1 - 0.001 17.4 17.0 0.0014 17.0 17.0 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG87390.1 - 0.006 16.1 18.7 0.0084 15.6 18.7 1.1 1 0 0 1 1 1 1 SDA1 PrmA PF06325.13 GBG87390.1 - 0.014 14.8 0.6 0.038 13.4 0.2 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) BUD22 PF09073.10 GBG87390.1 - 0.016 14.6 13.9 0.023 14.1 13.9 1.2 1 0 0 1 1 1 0 BUD22 Methyltransf_24 PF13578.6 GBG87390.1 - 0.049 14.7 0.0 0.11 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain rRNA_methylase PF06962.12 GBG87390.1 - 0.056 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative rRNA methylase Connexin PF00029.19 GBG87390.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Connexin Apt1 PF10351.9 GBG87390.1 - 0.5 9.2 2.6 0.68 8.7 2.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mpp10 PF04006.12 GBG87390.1 - 0.51 8.7 23.8 0.72 8.2 23.8 1.1 1 0 0 1 1 1 0 Mpp10 protein MukE PF04288.13 GBG87390.1 - 0.69 8.8 5.3 1.1 8.1 5.3 1.3 1 0 0 1 1 1 0 MukE-like family PTPRCAP PF15713.5 GBG87390.1 - 0.95 9.7 21.9 1.8 8.8 21.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CPSF100_C PF13299.6 GBG87390.1 - 1 9.5 4.9 1.9 8.6 4.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Sporozoite_P67 PF05642.11 GBG87390.1 - 3.6 5.6 11.7 5.1 5.1 11.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen eIF-3c_N PF05470.12 GBG87390.1 - 4.4 5.5 10.6 5.9 5.1 10.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SAPS PF04499.15 GBG87390.1 - 5.7 5.6 8.1 8.1 5.1 8.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GCIP PF13324.6 GBG87390.1 - 6.1 6.4 7.9 12 5.4 7.9 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Pep_deformylase PF01327.21 GBG87391.1 - 0.021 14.5 2.2 0.064 12.8 2.2 1.8 1 0 0 1 1 1 0 Polypeptide deformylase zf-FCS PF06467.14 GBG87391.1 - 0.089 12.7 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif RVT_1 PF00078.27 GBG87392.1 - 3.9e-28 98.5 0.1 6.4e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG87393.1 - 3.7e-28 98.6 0.1 5.3e-28 98.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEK_C PF08766.11 GBG87394.1 - 0.19 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain DUF1929 PF09118.11 GBG87395.1 - 0.043 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) RVT_1 PF00078.27 GBG87396.1 - 3.5e-22 79.0 0.1 6.6e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87396.1 - 1.7e-20 73.2 0.1 3.6e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87396.1 - 2.7e-14 53.0 0.0 6.8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG87396.1 - 2.5e-11 43.5 0.0 6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87396.1 - 3e-11 43.5 0.1 0.00011 22.4 0.0 3.0 2 1 1 3 3 3 2 Integrase core domain zf-H2C2 PF09337.10 GBG87396.1 - 1.1e-05 25.5 0.0 4.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger DEAD PF00270.29 GBG87397.1 - 3.9e-48 163.5 0.0 6.1e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG87397.1 - 1.2e-29 102.9 0.0 5.8e-29 100.7 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GBG87397.1 - 6.2e-07 28.9 0.1 9.4e-07 28.3 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GBG87397.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG87397.1 - 0.036 13.4 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit RNA_polI_A34 PF08208.11 GBG87397.1 - 0.077 13.1 0.0 0.077 13.1 0.0 2.4 3 1 1 4 4 4 0 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_M41 PF01434.18 GBG87398.1 - 5.7e-67 225.3 0.7 1.1e-66 224.4 0.7 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GBG87398.1 - 3.8e-42 143.8 0.0 7.6e-42 142.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG87398.1 - 2.5e-12 46.4 0.2 6.4e-12 45.1 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 GBG87398.1 - 1.4e-10 41.4 2.2 1.3e-09 38.3 1.8 2.6 2 1 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 GBG87398.1 - 0.00033 20.7 0.0 0.00095 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GBG87398.1 - 0.00036 20.8 0.0 0.12 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 GBG87398.1 - 0.00069 18.9 0.1 0.0016 17.7 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 GBG87398.1 - 0.0013 18.5 0.0 0.0037 17.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GBG87398.1 - 0.0035 17.7 0.7 0.082 13.3 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 GBG87398.1 - 0.018 15.2 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 GBG87398.1 - 0.027 14.6 0.0 0.087 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 GBG87398.1 - 0.028 14.9 0.1 0.082 13.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 GBG87398.1 - 0.034 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GBG87398.1 - 0.049 13.0 0.3 0.11 11.8 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ribosomal_L44 PF00935.19 GBG87400.1 - 4.4e-35 120.0 13.5 8.7e-35 119.0 13.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 Longin PF13774.6 GBG87402.1 - 3.2e-25 88.0 0.1 5.9e-25 87.1 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GBG87402.1 - 7.9e-18 64.0 0.4 7.9e-18 64.0 0.4 2.1 2 0 0 2 2 2 1 Synaptobrevin T2SSF PF00482.23 GBG87402.1 - 0.02 14.8 0.1 1.3 9.0 0.0 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F RRM_1 PF00076.22 GBG87402.1 - 0.073 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2924 PF11149.8 GBG87402.1 - 0.14 12.5 1.8 0.36 11.2 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) RVT_1 PF00078.27 GBG87404.1 - 4.4e-05 23.1 0.0 7.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG87404.1 - 0.0037 17.9 0.0 0.0077 16.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG87405.1 - 1.7e-16 60.4 0.1 2.6e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 GBG87405.1 - 0.0028 17.1 25.2 0.0039 16.6 25.2 1.1 1 0 0 1 1 1 1 BUD22 NPR3 PF03666.13 GBG87405.1 - 0.0092 14.8 3.9 0.012 14.5 3.9 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Mpp10 PF04006.12 GBG87405.1 - 0.052 12.0 28.7 0.08 11.4 28.7 1.3 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 GBG87405.1 - 0.096 11.5 6.1 0.15 10.9 6.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 GBG87405.1 - 0.31 10.6 15.1 0.44 10.1 15.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIF_alpha PF05793.12 GBG87405.1 - 1 7.9 26.3 1.6 7.2 26.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GBG87405.1 - 1.7 6.8 24.8 2.7 6.2 24.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG87405.1 - 1.9 6.6 34.9 2.7 6.1 34.9 1.1 1 0 0 1 1 1 0 Nop14-like family GREB1 PF15782.5 GBG87405.1 - 2.1 5.4 5.0 2.7 5.0 5.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SDA1 PF05285.12 GBG87405.1 - 3 7.2 38.3 4.6 6.6 38.3 1.2 1 0 0 1 1 1 0 SDA1 Peptidase_S64 PF08192.11 GBG87405.1 - 3.7 5.9 6.9 5.3 5.4 6.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 Cwf_Cwc_15 PF04889.12 GBG87405.1 - 6.2 6.5 29.1 10 5.8 29.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Hid1 PF12722.7 GBG87405.1 - 8.2 4.4 13.3 11 4.0 13.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3807 PF12720.7 GBG87405.1 - 8.7 6.6 25.1 14 5.9 25.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Arm PF00514.23 GBG87406.1 - 1.4e-05 25.0 1.4 0.00098 19.1 0.5 2.2 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GBG87406.1 - 0.0034 17.9 0.6 0.0078 16.7 0.2 1.7 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.22 GBG87406.1 - 0.0049 17.0 0.1 0.014 15.6 0.1 1.8 1 0 0 1 1 1 1 HEAT repeat HEAT_2 PF13646.6 GBG87406.1 - 0.038 14.4 0.2 0.06 13.7 0.2 1.4 1 1 0 1 1 1 0 HEAT repeats Cnd1 PF12717.7 GBG87406.1 - 0.075 13.1 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 RT_RNaseH_2 PF17919.1 GBG87407.1 - 3e-34 117.0 0.1 5.6e-34 116.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87407.1 - 2.3e-30 105.8 0.0 3.5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87407.1 - 8.2e-30 103.2 0.1 1.4e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BTRD1 PF17660.1 GBG87407.1 - 0.12 12.2 0.0 6.9 6.6 0.1 2.8 3 0 0 3 3 3 0 Bacterial tandem repeat domain 1 Arm PF00514.23 GBG87408.1 - 4.2e-16 58.4 6.0 2.1e-08 33.9 0.0 3.6 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat zf-CCHC PF00098.23 GBG87408.1 - 3.5e-07 30.0 3.3 1.2e-06 28.3 3.3 2.0 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG87408.1 - 5.6e-05 22.7 0.2 2.9 7.4 0.0 4.5 4 1 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT_EZ PF13513.6 GBG87408.1 - 0.013 16.0 4.5 1.6 9.3 0.2 2.9 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 GBG87408.1 - 0.066 13.6 2.5 0.65 10.4 0.3 3.0 1 1 1 2 2 2 0 HEAT repeats zf-CCHC_2 PF13696.6 GBG87408.1 - 0.077 12.8 1.9 0.17 11.7 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG87409.1 - 3.6e-33 114.9 0.0 7e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87409.1 - 1.1e-09 38.2 0.0 2.9e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG87409.1 - 1.7e-07 31.1 0.0 3.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87409.1 - 8.8e-06 26.3 0.0 2.6e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87409.1 - 1.1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87409.1 - 7.2e-05 23.3 0.0 0.00021 21.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease CCDC85 PF10226.9 GBG87409.1 - 0.0099 15.6 1.5 0.012 15.3 0.2 1.8 2 0 0 2 2 2 1 CCDC85 family HALZ PF02183.18 GBG87409.1 - 0.14 12.4 2.4 0.36 11.1 2.4 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper CCD48 PF15799.5 GBG87409.1 - 0.15 10.3 4.1 0.24 9.7 4.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 bZIP_2 PF07716.15 GBG87409.1 - 0.34 11.0 11.4 0.22 11.6 3.7 2.7 2 0 0 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 GBG87409.1 - 2.1 8.9 7.9 0.15 12.5 2.4 2.0 2 0 0 2 2 1 0 Cell division protein ZapB bZIP_1 PF00170.21 GBG87409.1 - 3.4 7.9 7.6 0.25 11.5 1.9 2.1 2 0 0 2 2 2 0 bZIP transcription factor GvpL_GvpF PF06386.11 GBG87409.1 - 5.6 6.8 7.6 12 5.8 7.6 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HEAT_2 PF13646.6 GBG87410.1 - 5.3e-06 26.7 0.5 0.0098 16.3 0.1 2.9 2 1 0 2 2 2 2 HEAT repeats Arm PF00514.23 GBG87410.1 - 1.2e-05 25.1 0.3 3.8 7.7 0.0 4.4 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GBG87410.1 - 6e-05 23.0 0.0 0.44 10.9 0.0 3.2 3 0 0 3 3 3 2 HEAT repeat DNA_alkylation PF08713.11 GBG87410.1 - 6.3e-05 22.8 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 DNA alkylation repair enzyme HEAT_EZ PF13513.6 GBG87410.1 - 0.0023 18.4 0.1 0.059 13.9 0.0 3.2 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 GBG87410.1 - 0.004 17.2 0.0 0.2 11.7 0.0 2.5 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_UF PF18817.1 GBG87410.1 - 0.02 15.1 0.2 1 9.7 0.0 3.1 3 0 0 3 3 3 0 Repeat of uncharacterized protein PH0542 CLASP_N PF12348.8 GBG87410.1 - 0.021 14.4 0.0 0.21 11.1 0.0 2.2 3 0 0 3 3 3 0 CLASP N terminal DRIM PF07539.12 GBG87410.1 - 0.054 11.8 0.0 1.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Down-regulated in metastasis Adaptin_N PF01602.20 GBG87410.1 - 0.22 10.1 0.1 3.2 6.2 0.0 2.4 2 1 0 2 2 2 0 Adaptin N terminal region EPL1 PF10513.9 GBG87411.1 - 2e-07 31.5 0.0 2e-07 31.5 0.0 3.4 4 0 0 4 4 4 1 Enhancer of polycomb-like RVT_1 PF00078.27 GBG87412.1 - 3.4e-31 108.5 0.0 5.8e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87412.1 - 4.4e-15 55.5 0.8 9.5e-15 54.5 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG87412.1 - 2.9e-13 49.7 0.0 1.3e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87412.1 - 2.3e-11 43.9 0.0 7.2e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG87412.1 - 0.00032 20.8 0.0 0.00082 19.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG87412.1 - 0.0052 17.0 0.0 0.02 15.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG87412.1 - 0.1 13.2 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG87413.1 - 1e-30 106.5 0.0 1.6e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87413.1 - 1.1e-12 48.0 0.0 1.8e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG87413.1 - 3.4e-05 23.6 0.1 0.53 9.9 0.1 3.3 2 1 1 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG87413.1 - 0.065 13.6 0.2 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 Transposase DDE domain GST_N_3 PF13417.6 GBG87415.1 - 3.1e-13 49.9 0.0 8.8e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG87415.1 - 4.2e-11 43.0 0.0 8.1e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GBG87415.1 - 1.7e-08 34.7 0.0 3.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GBG87415.1 - 2.3e-06 27.7 0.0 3.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GBG87415.1 - 0.00067 19.6 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GBG87415.1 - 0.00092 19.8 0.0 0.0016 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GBG87415.1 - 0.013 15.6 0.0 0.044 14.0 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Retrotrans_gag PF03732.17 GBG87416.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.6 4 0 0 4 4 4 0 Retrotransposon gag protein DcpS_C PF11969.8 GBG87418.1 - 5.8e-15 55.8 0.5 1.2e-14 54.8 0.5 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA_33 PF13671.6 GBG87418.1 - 2.9e-13 50.2 0.8 1.2e-12 48.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain zf-CCHH PF10283.9 GBG87418.1 - 9.3e-13 47.9 3.2 1.7e-12 47.1 3.2 1.5 1 0 0 1 1 1 1 PBZ domain Macro PF01661.21 GBG87418.1 - 9.2e-10 38.6 0.0 3.6e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Macro domain AAA_18 PF13238.6 GBG87418.1 - 0.00058 20.4 0.2 0.0025 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain HIT PF01230.23 GBG87418.1 - 0.00093 19.9 0.1 0.002 18.8 0.1 1.5 1 0 0 1 1 1 1 HIT domain Viral_helicase1 PF01443.18 GBG87418.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Peptidase_S24 PF00717.23 GBG87419.1 - 1.1e-11 44.5 0.2 2.1e-11 43.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 GBG87419.1 - 4.8e-11 42.6 0.0 1.3e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Caldesmon PF02029.15 GBG87419.1 - 2 7.1 4.6 3 6.5 4.6 1.2 1 0 0 1 1 1 0 Caldesmon Response_reg PF00072.24 GBG87420.1 - 4e-24 84.9 0.4 4.9e-22 78.2 0.0 2.7 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 GBG87420.1 - 3.6e-22 79.0 0.0 5.1e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RVT_1 PF00078.27 GBG87420.1 - 2.6e-10 40.2 0.0 4.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIA PF03153.13 GBG87421.1 - 0.039 14.0 40.1 0.053 13.5 40.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 GBG87421.1 - 2.2 7.9 24.2 3.2 7.3 23.2 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_primase_lrg PF04104.14 GBG87422.1 - 2.6e-85 286.0 0.0 3.3e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Mpp10 PF04006.12 GBG87423.1 - 4.2 5.7 36.9 5.4 5.3 36.9 1.1 1 0 0 1 1 1 0 Mpp10 protein SURF2 PF05477.11 GBG87423.1 - 9.2 5.9 20.1 12 5.6 20.1 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DDE_Tnp_4 PF13359.6 GBG87424.1 - 1.9e-28 99.2 0.0 2e-27 95.8 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87424.1 - 5.5e-14 52.2 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DUF1336 PF07059.12 GBG87425.1 - 2.3e-23 83.4 0.0 3.8e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PRR18 PF15671.5 GBG87425.1 - 1.3 8.8 11.0 2.9 7.7 11.0 1.5 1 0 0 1 1 1 0 Proline-rich protein family 18 Castor_Poll_mid PF06241.12 GBG87426.1 - 3.8e-27 94.3 0.0 8.2e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel DUF4051 PF13260.6 GBG87426.1 - 0.0047 16.6 0.1 0.0097 15.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4051) TrkA_C PF02080.21 GBG87426.1 - 0.0062 16.3 0.0 0.034 14.0 0.0 2.3 2 0 0 2 2 2 1 TrkA-C domain Pro_isomerase PF00160.21 GBG87427.1 - 2.1e-53 180.8 0.1 4.9e-53 179.6 0.1 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 GBG87427.1 - 9.4e-08 32.6 2.7 0.044 14.7 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG87427.1 - 0.0087 16.3 0.0 4.8 7.6 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 GBG87427.1 - 0.014 15.0 0.0 2.1 7.9 0.0 2.5 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Nop14 PF04147.12 GBG87428.1 - 10 4.2 49.8 13 3.8 49.8 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG87429.1 - 3.3e-32 110.5 0.0 6e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87429.1 - 1.9e-19 69.9 0.0 3.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ldl_recept_a PF00057.18 GBG87430.1 - 1.5e-49 165.9 126.2 3.7e-07 30.3 3.2 10.8 9 1 1 10 10 10 10 Low-density lipoprotein receptor domain class A zf-CCHC PF00098.23 GBG87431.1 - 6.3e-06 26.0 4.0 6.3e-06 26.0 4.0 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG87431.1 - 0.049 13.5 2.9 0.084 12.7 2.9 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG87431.1 - 0.15 11.8 1.1 0.36 10.6 1.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RT_RNaseH_2 PF17919.1 GBG87432.1 - 1.2e-29 102.2 0.0 2.2e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87432.1 - 2.2e-19 69.7 0.0 3.8e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87432.1 - 0.0084 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) efThoc1 PF11957.8 GBG87433.1 - 7.6e-70 236.0 11.8 5.7e-48 163.8 8.3 3.9 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor Cas1_AcylT PF07779.12 GBG87434.1 - 2.6e-88 297.0 18.4 3.6e-88 296.6 18.4 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF3397 PF11877.8 GBG87434.1 - 0.015 15.5 5.9 0.015 15.5 5.9 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3397) TENA_THI-4 PF03070.16 GBG87435.1 - 1.9e-12 47.5 0.0 4.6e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 TENA/THI-4/PQQC family TSP_1 PF00090.19 GBG87436.1 - 0.56 10.5 10.8 3.6 7.9 0.5 3.6 3 0 0 3 3 3 0 Thrombospondin type 1 domain CLP_protease PF00574.23 GBG87437.1 - 8.5e-43 146.4 0.0 1.4e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Clp protease RVT_1 PF00078.27 GBG87438.1 - 1.2e-25 90.4 0.0 1.9e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG87440.1 - 3.1e-31 108.3 0.0 7.1e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87440.1 - 0.00011 22.0 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG87441.1 - 3.8e-15 55.7 0.0 8.3e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87441.1 - 7.9e-14 51.8 0.0 1.6e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RXLR PF16810.5 GBG87441.1 - 0.098 13.1 2.2 1.6 9.1 0.6 2.9 2 1 1 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity Topo_Zn_Ribbon PF08272.11 GBG87442.1 - 0.014 15.0 0.3 0.025 14.2 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG87442.1 - 0.03 14.4 1.9 0.047 13.8 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG87444.1 - 2.9e-12 46.7 0.0 4.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG87445.1 - 5.7e-19 68.0 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87445.1 - 2.3e-16 60.0 0.0 6.3e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87445.1 - 3.1e-10 40.3 0.0 6.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG87445.1 - 8.6e-07 28.7 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG87445.1 - 2.2e-05 25.0 0.0 5.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87445.1 - 0.00012 22.6 0.0 0.00027 21.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG87445.1 - 0.0013 19.0 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87445.1 - 0.0034 17.2 0.2 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease GRP PF07172.11 GBG87446.1 - 0.015 16.0 9.4 0.015 16.0 9.4 2.0 2 1 1 3 3 3 0 Glycine rich protein family DIMCO_N PF16844.5 GBG87446.1 - 0.64 10.4 2.7 11 6.4 0.0 2.9 1 1 2 3 3 3 0 Dinitrogenase iron-molybdenum cofactor, N-terminal RT_RNaseH_2 PF17919.1 GBG87447.1 - 1.5e-29 101.9 0.0 3.3e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87447.1 - 3.5e-18 65.8 0.0 8.1e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87447.1 - 2.7e-16 59.7 0.2 2.4e-15 56.7 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG87447.1 - 2.9e-06 27.5 0.0 8.5e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain GIY-YIG PF01541.24 GBG87448.1 - 2.2e-09 37.4 0.3 8.5e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 GIY-YIG catalytic domain SAP PF02037.27 GBG87448.1 - 0.0057 16.4 0.4 0.021 14.6 0.4 2.0 1 0 0 1 1 1 1 SAP domain zf-CCHC_5 PF14787.6 GBG87448.1 - 0.43 10.3 6.8 1 9.1 6.8 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF659 PF04937.15 GBG87451.1 - 2.6e-23 82.6 0.0 7.3e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87451.1 - 2.4e-05 24.0 0.0 6.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Borrelia_P83 PF05262.11 GBG87451.1 - 7.1 5.0 13.6 10 4.5 13.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein GTP_EFTU PF00009.27 GBG87452.1 - 2.3e-46 157.8 0.0 3.3e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GBG87452.1 - 5.3e-31 107.2 0.1 1.7e-30 105.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GBG87452.1 - 3.1e-09 37.1 0.2 1.1e-08 35.4 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 GBG87452.1 - 0.0027 17.6 0.4 0.019 14.9 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 GBG87452.1 - 0.004 17.2 0.0 0.023 14.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RVT_1 PF00078.27 GBG87453.1 - 2.2e-14 53.5 0.0 4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87453.1 - 5.6e-08 32.6 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87453.1 - 2.1e-07 31.5 0.0 5.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87453.1 - 2e-05 25.0 0.0 8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87453.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG87453.1 - 0.0058 16.9 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein INTAP PF16617.5 GBG87453.1 - 6.1 7.2 10.0 0.91 9.9 5.2 2.1 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region Dus PF01207.17 GBG87454.1 - 3.3e-66 223.5 0.0 4.7e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 GBG87454.1 - 0.0034 16.9 0.0 0.0074 15.8 0.0 1.5 2 0 0 2 2 2 1 Histidine biosynthesis protein GTP_EFTU PF00009.27 GBG87455.1 - 1.4e-43 148.7 0.0 2e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GBG87455.1 - 8e-32 109.9 0.2 2.3e-31 108.4 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GBG87455.1 - 4.1e-10 39.9 0.2 1.4e-09 38.2 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GBG87455.1 - 0.0014 18.6 0.1 0.0076 16.3 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RVT_1 PF00078.27 GBG87456.1 - 1.2e-30 106.7 0.1 1.8e-30 106.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87456.1 - 4.2e-30 103.7 0.0 7.7e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87456.1 - 8.1e-23 80.7 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87457.1 - 8.6e-32 109.2 0.0 1.7e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87457.1 - 2.3e-31 109.0 0.0 4e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87457.1 - 1.2e-27 96.2 0.0 2.3e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG87457.1 - 8e-06 26.3 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87457.1 - 4.3e-05 24.1 0.0 7.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87457.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF5095 PF17016.5 GBG87457.1 - 0.15 11.8 0.2 0.15 11.8 0.2 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5095) DUF1758 PF05585.12 GBG87457.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG87457.1 - 0.19 11.6 0.1 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease DUF3169 PF11368.8 GBG87458.1 - 0.065 12.7 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Phage_Gp23 PF10669.9 GBG87458.1 - 0.071 13.4 5.9 0.18 12.1 5.9 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) 7tm_6 PF02949.20 GBG87458.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 7tm Odorant receptor NicO PF03824.16 GBG87458.1 - 0.21 10.9 0.1 0.81 9.0 0.0 1.9 2 0 0 2 2 2 0 High-affinity nickel-transport protein VID27_N PF17748.1 GBG87458.1 - 2.2 8.1 5.5 4.6 7.1 5.5 1.4 1 0 0 1 1 1 0 VID27 N-terminal region CENP-B_dimeris PF09026.10 GBG87458.1 - 2.3 8.7 6.7 6.3 7.2 6.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DivIC PF04977.15 GBG87459.1 - 0.022 14.5 0.5 0.022 14.5 0.5 5.0 2 2 2 4 4 4 0 Septum formation initiator TMCO5 PF14992.6 GBG87459.1 - 0.072 12.7 15.8 0.63 9.6 2.7 2.4 2 1 0 2 2 2 0 TMCO5 family APG6_N PF17675.1 GBG87459.1 - 1.1 9.8 24.8 1.4 9.4 3.9 3.5 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF641 PF04859.12 GBG87459.1 - 2.5 8.4 7.5 0.43 10.9 0.7 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TolA_bind_tri PF16331.5 GBG87459.1 - 2.8 8.1 11.5 0.5 10.5 1.8 3.5 4 1 0 4 4 4 0 TolA binding protein trimerisation Fez1 PF06818.15 GBG87459.1 - 3 8.3 16.6 7.2 7.0 3.9 2.3 2 0 0 2 2 2 0 Fez1 zf-RING_2 PF13639.6 GBG87460.1 - 1.3e-05 25.4 1.4 1.3e-05 25.4 1.4 6.7 7 1 0 7 7 7 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG87460.1 - 0.00022 21.1 0.2 0.00022 21.1 0.2 5.8 7 0 0 7 7 7 2 RING-type zinc-finger zf-RING_11 PF17123.5 GBG87460.1 - 0.0044 16.7 1.5 0.0044 16.7 1.5 3.1 3 0 0 3 3 3 1 RING-like zinc finger RT_RNaseH_2 PF17919.1 GBG87461.1 - 3.1e-31 107.4 0.0 7.7e-31 106.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87461.1 - 2.2e-26 92.2 0.1 4.3e-26 91.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87461.1 - 2.4e-17 63.2 0.0 5.7e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87461.1 - 7.5e-17 61.2 0.0 1.8e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG87461.1 - 0.0013 18.9 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_4 PF14392.6 GBG87461.1 - 0.055 13.2 0.5 2.1 8.1 0.2 2.8 2 0 0 2 2 2 0 Zinc knuckle Rhamno_transf PF11316.8 GBG87461.1 - 0.12 11.8 0.1 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Putative rhamnosyl transferase TRM13 PF05206.14 GBG87461.1 - 0.22 11.0 2.9 0.4 10.2 2.9 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 K_channel_TID PF07941.11 GBG87462.1 - 0.0071 16.8 19.6 0.029 14.8 19.6 2.0 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain AAA_11 PF13086.6 GBG87462.1 - 0.041 13.7 9.9 0.051 13.3 9.9 1.1 1 0 0 1 1 1 0 AAA domain DUF913 PF06025.12 GBG87462.1 - 0.058 12.4 4.0 0.074 12.0 4.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BSP_II PF05432.11 GBG87462.1 - 0.26 10.9 21.5 0.35 10.5 21.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4775 PF16001.5 GBG87462.1 - 0.35 10.2 24.8 0.41 10.0 24.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) DUF4667 PF15700.5 GBG87462.1 - 1.5 8.8 8.9 2.1 8.4 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) CDC27 PF09507.10 GBG87462.1 - 4.4 6.6 31.5 5.8 6.2 31.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Atg14 PF10186.9 GBG87462.1 - 7.8 5.5 15.5 8.8 5.3 15.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Presenilin PF01080.17 GBG87462.1 - 8.7 5.0 20.8 10 4.8 20.8 1.0 1 0 0 1 1 1 0 Presenilin 2_5_RNA_ligase2 PF13563.6 GBG87463.1 - 8.1 6.3 8.9 1 9.2 0.4 4.3 3 0 0 3 3 3 0 2'-5' RNA ligase superfamily PIF1 PF05970.14 GBG87465.1 - 1.9e-44 152.3 0.0 3e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Syntaxin-6_N PF09177.11 GBG87465.1 - 0.021 15.4 1.6 11 6.7 0.1 3.0 4 0 0 4 4 4 0 Syntaxin 6, N-terminal zf-CCHC_5 PF14787.6 GBG87465.1 - 0.069 12.9 2.6 0.19 11.5 2.6 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RBD-FIP PF09457.10 GBG87465.1 - 0.37 10.7 1.8 0.95 9.4 1.8 1.7 1 0 0 1 1 1 0 FIP domain rve PF00665.26 GBG87466.1 - 3.5e-14 53.0 0.0 1.6e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG87466.1 - 2.4e-05 24.8 0.0 6.8e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG87466.1 - 0.00048 20.4 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87466.1 - 0.00074 20.1 0.0 0.002 18.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG87466.1 - 0.0021 18.3 2.4 0.0069 16.6 0.1 2.7 2 1 1 3 3 3 1 Retrotransposon gag protein rve_3 PF13683.6 GBG87466.1 - 0.0039 16.9 0.0 0.017 14.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG87466.1 - 0.016 15.3 0.2 0.053 13.6 0.2 1.9 1 0 0 1 1 1 0 Integrase zinc binding domain Asp_protease PF09668.10 GBG87466.1 - 0.032 14.0 0.2 0.086 12.6 0.2 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF1664 PF07889.12 GBG87466.1 - 0.16 12.0 0.7 2.6 8.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Asp_protease_2 PF13650.6 GBG87467.1 - 0.0025 18.4 0.0 0.053 14.2 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87467.1 - 0.035 14.7 0.1 0.12 13.0 0.0 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease GerE PF00196.19 GBG87467.1 - 0.07 12.7 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family RVT_1 PF00078.27 GBG87469.1 - 1.8e-27 96.3 0.1 2.8e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG87469.1 - 2.8e-07 31.0 0.0 6.9e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87469.1 - 1e-06 29.3 0.0 2.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87469.1 - 1.2e-06 28.3 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87469.1 - 3.7e-05 23.5 0.0 6.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Flot PF15975.5 GBG87469.1 - 2.5 8.3 9.3 5.1 7.3 9.3 1.5 1 0 0 1 1 1 0 Flotillin DUF2937 PF11157.8 GBG87469.1 - 5.2 6.8 8.2 16 5.1 8.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) RT_RNaseH_2 PF17919.1 GBG87470.1 - 9.1e-11 41.7 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87470.1 - 1.7e-07 31.0 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87470.1 - 0.00033 20.9 0.0 0.00058 20.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG87470.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 UPF0561 PF10573.9 GBG87471.1 - 0.18 11.9 1.6 0.29 11.2 0.6 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0561 BSP_II PF05432.11 GBG87471.1 - 1.3 8.6 13.3 0.049 13.3 7.4 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4391 PF14335.6 GBG87472.1 - 0.47 10.1 7.5 0.82 9.3 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF3767 PF12597.8 GBG87472.1 - 0.73 9.7 5.1 0.26 11.1 2.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3767) Tho2 PF11262.8 GBG87472.1 - 0.87 8.7 6.6 1.2 8.3 6.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Peptidase_S49_N PF08496.10 GBG87472.1 - 1.2 9.1 6.2 2.3 8.2 6.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMPIT PF07851.13 GBG87472.1 - 1.5 8.0 5.3 3.6 6.7 5.2 1.6 2 0 0 2 2 2 0 TMPIT-like protein MCU PF04678.13 GBG87473.1 - 0.3 11.2 4.1 0.53 10.4 4.1 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4407 PF14362.6 GBG87473.1 - 0.5 9.7 8.9 0.6 9.4 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tho2 PF11262.8 GBG87473.1 - 0.66 9.1 7.4 0.9 8.7 7.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMPIT PF07851.13 GBG87473.1 - 4.3 6.5 9.4 5.7 6.1 9.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein ALMT PF11744.8 GBG87473.1 - 7.5 5.3 7.4 9 5.0 7.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter EGF_CA PF07645.15 GBG87474.1 - 2.2e-12 46.9 43.9 5.9e-08 32.8 5.5 4.5 3 1 1 4 4 4 4 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 GBG87474.1 - 5.2e-08 33.1 30.3 0.033 14.5 2.5 4.6 4 1 0 4 4 4 4 Pvs28 EGF domain cEGF PF12662.7 GBG87474.1 - 8.2e-08 32.0 23.2 0.0056 16.6 0.5 4.6 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF PF00008.27 GBG87474.1 - 0.00017 21.8 25.9 0.00031 21.0 9.0 5.1 5 0 0 5 5 5 2 EGF-like domain EGF_3 PF12947.7 GBG87474.1 - 0.00054 20.1 34.8 0.19 11.9 3.1 5.0 4 1 1 5 5 5 4 EGF domain hEGF PF12661.7 GBG87474.1 - 0.0081 16.8 26.3 0.012 16.2 9.8 6.4 6 1 0 6 6 6 2 Human growth factor-like EGF FXa_inhibition PF14670.6 GBG87474.1 - 0.015 15.5 46.1 0.51 10.7 7.4 4.9 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 GBG87474.1 - 0.037 14.1 34.6 0.082 13.0 5.6 4.8 4 1 0 4 4 4 0 MSP1 EGF domain 1 DUF659 PF04937.15 GBG87475.1 - 1.8e-28 99.3 0.3 2.9e-28 98.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87475.1 - 0.00026 20.7 0.1 0.00082 19.1 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region EMI PF07546.13 GBG87476.1 - 0.065 14.0 0.2 0.64 10.8 0.1 2.3 2 0 0 2 2 2 0 EMI domain MLVIN_C PF18697.1 GBG87480.1 - 0.02 15.0 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain TFIIF_alpha PF05793.12 GBG87480.1 - 1.2 7.7 12.5 1.4 7.4 12.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lin-8 PF03353.15 GBG87480.1 - 1.8 8.1 6.5 2.4 7.7 6.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 GBG87480.1 - 3.6 6.8 13.7 4.8 6.4 13.7 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG87480.1 - 4.3 5.5 9.0 5.5 5.1 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 GBG87481.1 - 6.5e-38 130.6 0.0 1.1e-37 129.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG87481.1 - 1.1e-35 123.2 0.0 7e-35 120.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG87481.1 - 8.8e-05 22.5 0.1 0.00025 21.0 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG87481.1 - 0.0021 16.9 0.1 0.0062 15.4 0.1 1.7 1 0 0 1 1 1 1 Fungal protein kinase PGAP1 PF07819.13 GBG87482.1 - 0.00032 20.5 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GBG87482.1 - 0.00061 20.5 0.1 0.00061 20.5 0.1 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 GBG87482.1 - 0.026 14.0 0.0 0.072 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF829 PF05705.14 GBG87482.1 - 0.078 12.9 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Hydrolase_4 PF12146.8 GBG87482.1 - 0.12 11.6 0.1 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ANAPC15 PF15243.6 GBG87483.1 - 3.7e-11 43.3 10.6 4.1e-11 43.1 10.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 Miga PF10265.9 GBG87484.1 - 4.1 6.3 8.0 5.1 5.9 8.0 1.1 1 0 0 1 1 1 0 Mitoguardin TERB2 PF15101.6 GBG87484.1 - 4.5 7.3 6.8 5.7 6.9 6.3 1.5 1 1 0 1 1 1 0 Telomere-associated protein TERB2 Apt1 PF10351.9 GBG87484.1 - 9 5.0 13.9 10 4.9 13.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RdRP PF05183.12 GBG87486.1 - 6.3e-190 632.7 0.0 8.2e-190 632.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 GBG87486.1 - 3.6e-06 26.7 0.0 7.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Occludin_ELL PF07303.13 GBG87489.1 - 0.41 11.4 10.6 1.1 10.1 1.9 3.6 2 1 2 4 4 4 0 Occludin homology domain LMBR1 PF04791.16 GBG87489.1 - 3 6.6 8.8 4.6 6.0 8.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Myb_DNA-bind_4 PF13837.6 GBG87490.1 - 2.4e-11 43.9 1.1 4e-11 43.1 1.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 GBG87491.1 - 0.01 15.9 1.8 0.025 14.7 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle Histone PF00125.24 GBG87492.1 - 4.8e-24 85.2 0.9 1.1e-23 84.0 0.9 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Nop14 PF04147.12 GBG87492.1 - 6.9 4.8 13.7 9.9 4.2 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG87493.1 - 4.6e-29 100.4 0.0 3.2e-28 97.7 0.0 2.4 4 0 0 4 4 4 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87493.1 - 2.5e-28 98.4 0.0 1.5e-27 95.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87493.1 - 1.3e-12 47.7 0.1 2.4e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG87493.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.5 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FUN14 PF04930.15 GBG87495.1 - 0.81 10.1 6.2 0.4 11.1 0.5 2.5 2 1 0 2 2 2 0 FUN14 family Rieske PF00355.26 GBG87496.1 - 4e-13 49.1 0.0 8.1e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 GBG87496.1 - 0.0012 18.7 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain OmpW PF03922.14 GBG87496.1 - 0.082 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 OmpW family RVT_1 PF00078.27 GBG87497.1 - 1.7e-26 93.1 0.5 3e-26 92.3 0.5 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3054 PF11255.8 GBG87497.1 - 2e-22 79.7 4.9 4.5e-22 78.7 4.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3054) RT_RNaseH_2 PF17919.1 GBG87497.1 - 1.9e-18 66.4 0.0 5e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87497.1 - 1.5e-06 28.4 0.0 4.2e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glyco_hydro_46 PF01374.18 GBG87499.1 - 8.4e-43 146.4 0.0 9.7e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Glyco_hydro_46 PF01374.18 GBG87501.1 - 1.8e-41 142.1 0.0 2.1e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 DUF659 PF04937.15 GBG87502.1 - 5.8e-20 71.7 0.0 8.2e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Phlebovirus_NSM PF07246.11 GBG87506.1 - 0.094 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF659 PF04937.15 GBG87507.1 - 5.4e-14 52.3 0.1 9.1e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87507.1 - 0.00035 20.3 0.2 0.00087 19.0 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AphA_like PF14557.6 GBG87507.1 - 0.15 11.8 0.4 0.66 9.7 0.2 2.0 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator rve PF00665.26 GBG87508.1 - 1.2e-05 25.5 0.0 4.1e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG87508.1 - 0.00087 19.5 0.1 0.00087 19.5 0.1 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein Tudor-knot PF11717.8 GBG87508.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain RT_RNaseH PF17917.1 GBG87509.1 - 1.8e-20 73.2 0.0 1.8e-20 73.2 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87509.1 - 3.3e-17 62.3 0.1 1.5e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87509.1 - 0.027 14.6 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain Baculo_PEP_C PF04513.12 GBG87509.1 - 1.2 9.1 12.8 0.15 12.1 3.1 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5403 PF17395.2 GBG87509.1 - 8.6 6.7 6.7 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5403) Dala_Dala_lig_C PF07478.13 GBG87510.1 - 2e-08 34.0 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 GBG87510.1 - 2.4e-08 34.4 0.1 4.9e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus GARS_A PF01071.19 GBG87510.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pesticin PF16754.5 GBG87510.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term Dala_Dala_lig_N PF01820.21 GBG87512.1 - 8.1e-09 35.9 0.0 1.6e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus Dala_Dala_lig_C PF07478.13 GBG87512.1 - 0.00061 19.4 0.0 0.00076 19.1 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 GBG87512.1 - 0.062 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF4028 PF13220.6 GBG87512.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) NOA36 PF06524.12 GBG87513.1 - 0.1 11.9 9.4 0.11 11.8 9.4 1.1 1 0 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.12 GBG87513.1 - 0.83 9.4 6.6 0.84 9.4 6.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RPA43_OB PF17875.1 GBG87513.1 - 1.8 9.2 8.1 2.9 8.5 8.1 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Presenilin PF01080.17 GBG87513.1 - 3.3 6.4 3.2 3.2 6.4 3.2 1.1 1 0 0 1 1 1 0 Presenilin Nucleo_P87 PF07267.11 GBG87513.1 - 3.9 6.2 10.9 4.7 5.9 10.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 GBG87513.1 - 5 5.3 13.9 5.3 5.2 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DDE_Tnp_4 PF13359.6 GBG87514.1 - 1.2e-15 57.6 0.0 1.8e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87514.1 - 1.8e-08 34.2 0.0 2.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Dala_Dala_lig_N PF01820.21 GBG87514.1 - 1.6e-05 25.3 0.0 3.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus PapG_C PF03628.13 GBG87514.1 - 0.063 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 PapG chaperone-binding domain DDE_Tnp_1 PF01609.21 GBG87514.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Response_reg PF00072.24 GBG87515.1 - 5.9e-26 90.8 3.6 5.7e-16 58.7 0.0 4.9 5 0 0 5 5 5 3 Response regulator receiver domain HATPase_c PF02518.26 GBG87515.1 - 1.9e-23 83.1 0.0 4.1e-16 59.5 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GBG87515.1 - 7.4e-18 64.4 0.0 2.5e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CHASE PF03924.13 GBG87515.1 - 5e-07 29.8 0.0 0.0069 16.3 0.1 2.3 2 0 0 2 2 2 2 CHASE domain Myb_DNA-bind_4 PF13837.6 GBG87516.1 - 1.6e-10 41.2 5.7 3.1e-09 37.1 3.0 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG87516.1 - 0.0011 19.3 2.9 0.0051 17.1 1.1 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG87516.1 - 0.039 14.0 0.6 0.13 12.3 0.7 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG87518.1 - 1.3e-09 38.3 6.4 1.1e-08 35.3 3.1 2.7 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG87518.1 - 0.0041 17.4 2.5 0.016 15.5 1.1 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG87518.1 - 0.15 12.1 0.8 0.4 10.8 0.7 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG87519.1 - 2.2e-18 66.4 0.0 2.9e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87519.1 - 3.2e-06 26.9 0.0 4.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 GBG87520.1 - 8.7e-29 100.2 0.0 1.3e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87520.1 - 1.9e-12 47.2 0.0 3.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG87520.1 - 0.00066 19.4 0.4 0.48 10.0 0.2 2.6 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG87520.1 - 0.15 12.4 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain N6_N4_Mtase PF01555.18 GBG87521.1 - 5.8e-07 29.5 0.0 1e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 DNA methylase CAF1 PF04857.20 GBG87522.1 - 0.37 9.9 2.7 0.21 10.7 0.4 1.7 2 0 0 2 2 2 0 CAF1 family ribonuclease Histone PF00125.24 GBG87523.1 - 8e-20 71.5 0.5 1.6e-19 70.5 0.2 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RVT_1 PF00078.27 GBG87524.1 - 0.001 18.6 0.0 0.48 9.9 0.0 2.6 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG87527.1 - 2.6e-17 63.1 0.0 4e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG87527.1 - 1.5e-07 31.9 0.0 4.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87527.1 - 8.6e-07 29.4 0.0 2.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87527.1 - 1.7e-06 27.8 0.0 3.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87527.1 - 6.3e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG87529.1 - 9.5e-12 44.7 0.0 1.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 GBG87529.1 - 1.1e-09 38.2 0.1 1.1e-09 38.2 0.1 3.0 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG87529.1 - 2.6e-09 37.3 0.1 9.7e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG87529.1 - 0.0017 18.5 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG87530.1 - 6.7e-25 87.9 0.1 1.2e-24 87.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87530.1 - 2.6e-06 27.3 0.0 1.3e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87530.1 - 0.0028 18.2 0.0 0.0071 17.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87530.1 - 0.0061 17.1 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG87530.1 - 0.08 13.2 0.0 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG87530.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.12 GBG87530.1 - 1.7 9.3 7.6 0.46 11.1 1.3 3.0 2 1 1 3 3 3 0 SlyX RVT_1 PF00078.27 GBG87532.1 - 8.7e-17 61.4 0.0 1.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG87532.1 - 0.069 13.4 0.1 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein FAD_binding_4 PF01565.23 GBG87533.1 - 6.4e-14 51.9 0.0 1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Adeno_E3 PF06040.11 GBG87535.1 - 0.4 10.9 0.1 0.4 10.9 0.1 1.8 2 1 0 2 2 2 0 Adenovirus E3 protein QWRF PF04484.12 GBG87535.1 - 1 9.1 7.6 1.4 8.6 7.6 1.2 1 0 0 1 1 1 0 QWRF family cPLA2_C2 PF18695.1 GBG87536.1 - 0.0039 17.2 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain CYTH PF01928.21 GBG87536.1 - 0.16 11.9 3.5 0.25 11.2 3.5 1.3 1 0 0 1 1 1 0 CYTH domain TrbH PF07283.11 GBG87537.1 - 0.087 13.0 0.0 0.48 10.6 0.0 1.9 1 1 1 2 2 2 0 Conjugal transfer protein TrbH RT_RNaseH_2 PF17919.1 GBG87538.1 - 6.9e-31 106.3 0.2 2.3e-30 104.6 0.2 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87538.1 - 2.7e-25 89.2 0.1 6e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87538.1 - 3.3e-23 82.0 0.1 9.4e-23 80.5 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87538.1 - 1.1e-16 60.6 0.1 2.6e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87538.1 - 4.3e-15 56.0 1.2 3e-14 53.2 0.0 2.9 3 0 0 3 3 3 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG87539.1 - 4.2e-23 81.3 0.0 1.5e-22 79.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87539.1 - 1.4e-22 80.0 0.0 3.7e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87539.1 - 1.6e-16 60.1 0.1 3.6e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG87539.1 - 0.023 14.9 0.5 0.048 13.9 0.1 1.8 2 0 0 2 2 2 0 H2C2 zinc finger CHD5 PF04420.14 GBG87539.1 - 0.5 10.2 2.9 1.1 9.1 2.9 1.5 1 0 0 1 1 1 0 CHD5-like protein VIR_N PF15912.5 GBG87540.1 - 1.3 8.5 16.1 4.4 6.8 16.1 1.9 1 0 0 1 1 1 0 Virilizer, N-terminal DBD_Tnp_Mut PF03108.15 GBG87542.1 - 2.1e-15 56.5 0.1 3.9e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 MuDR family transposase Peptidase_M16_C PF05193.21 GBG87542.1 - 0.023 14.7 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M16 inactive domain DUF4127 PF13552.6 GBG87542.1 - 0.04 12.5 0.0 0.057 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) GRDP-like PF07173.12 GBG87542.1 - 0.041 14.5 0.0 0.058 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like Macoilin PF09726.9 GBG87543.1 - 5.8 5.3 7.3 7.7 4.9 7.3 1.2 1 0 0 1 1 1 0 Macoilin family TMF_TATA_bd PF12325.8 GBG87544.1 - 0.2 11.9 13.8 0.79 10.0 1.4 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3006 PF11213.8 GBG87544.1 - 4.4 7.6 6.4 4.6 7.6 3.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) RVT_1 PF00078.27 GBG87545.1 - 2.2e-27 96.0 0.1 2.8e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG87545.1 - 0.12 11.4 0.0 0.27 10.3 0.0 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 Secretin_N PF03958.17 GBG87546.1 - 0.092 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain SDA1 PF05285.12 GBG87547.1 - 0.013 14.9 32.4 0.016 14.7 32.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG87547.1 - 0.11 10.8 25.1 0.17 10.1 25.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG87547.1 - 0.15 10.3 36.4 0.2 9.8 36.4 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG87547.1 - 0.31 10.6 16.2 0.47 10.0 16.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF913 PF06025.12 GBG87547.1 - 1.4 7.9 6.9 1.8 7.4 6.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 GBG87547.1 - 1.6 7.4 12.1 1.9 7.2 12.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein YL1 PF05764.13 GBG87547.1 - 2 8.5 36.8 2.8 8.0 36.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG87547.1 - 5.4 6.2 35.4 7.9 5.7 35.4 1.2 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 GBG87548.1 - 0.099 12.5 7.2 0.15 12.0 7.2 1.4 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 GBG87548.1 - 0.57 8.7 3.9 0.72 8.3 3.9 1.1 1 0 0 1 1 1 0 Macoilin family Mucin PF01456.17 GBG87549.1 - 0.00072 19.6 2.4 0.0011 18.9 2.4 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein SelK_SelG PF10961.8 GBG87549.1 - 0.05 14.2 1.3 0.33 11.6 0.5 2.5 2 0 0 2 2 2 0 Selenoprotein SelK_SelG RT_RNaseH_2 PF17919.1 GBG87550.1 - 1.2e-27 95.8 0.0 2.9e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87550.1 - 4.1e-25 88.1 0.0 7.7e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87550.1 - 4.7e-14 52.4 0.1 7.1e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG87550.1 - 0.074 12.9 0.1 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) Na_trans_assoc PF06512.13 GBG87550.1 - 1.1 9.6 12.3 1.6 9.0 12.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG87550.1 - 7.3 5.9 23.8 10 5.4 23.8 1.1 1 0 0 1 1 1 0 SDA1 U-box PF04564.15 GBG87551.1 - 2.1e-25 88.7 0.0 4.3e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 GBG87551.1 - 5.1e-14 51.4 3.3 1.8e-06 27.5 0.5 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG87551.1 - 9.4e-12 44.1 1.9 0.00011 22.1 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GBG87551.1 - 1.9e-08 33.8 0.0 0.00061 19.4 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 GBG87551.1 - 7e-07 29.2 0.1 0.073 13.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-NOSIP PF15906.5 GBG87551.1 - 2.7e-05 24.2 0.0 7.8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_14 PF13428.6 GBG87551.1 - 0.0001 22.8 0.2 0.028 15.2 0.0 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GBG87551.1 - 0.00015 22.0 3.4 0.0092 16.3 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG87551.1 - 0.001 19.7 0.0 0.49 11.1 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 GBG87551.1 - 0.0014 19.4 0.0 0.0057 17.4 0.0 2.0 1 1 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_15 PF13429.6 GBG87551.1 - 0.054 12.7 0.1 0.082 12.1 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG87551.1 - 0.29 11.5 2.6 18 5.9 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Nop14 PF04147.12 GBG87554.1 - 0.37 9.0 22.6 0.45 8.7 22.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG87554.1 - 0.86 9.0 26.4 1.1 8.6 26.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG87554.1 - 0.89 8.8 25.0 1.2 8.4 25.0 1.1 1 0 0 1 1 1 0 BUD22 DUF2201_N PF13203.6 GBG87554.1 - 1.1 8.7 6.3 1.5 8.3 6.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.14 GBG87554.1 - 2 6.6 15.1 3.1 6.0 15.1 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG87554.1 - 7.6 5.9 15.9 13 5.0 15.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RecA PF00154.21 GBG87556.1 - 0.041 13.3 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Paf1 PF03985.13 GBG87557.1 - 0.21 10.6 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Paf1 DUF569 PF04601.13 GBG87558.1 - 0.013 15.2 0.0 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF569) Rrf2 PF02082.20 GBG87558.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator EF-hand_7 PF13499.6 GBG87560.1 - 2.7e-28 98.2 9.4 4.2e-14 52.7 3.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG87560.1 - 4.5e-24 82.1 20.3 2e-06 26.9 0.8 5.0 4 1 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 GBG87560.1 - 6.7e-22 75.9 17.4 3.1e-07 29.6 0.7 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 GBG87560.1 - 1.5e-17 62.0 31.6 5.9e-07 28.9 0.1 5.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 GBG87560.1 - 7.6e-17 60.9 15.2 1.3e-08 34.6 4.0 4.4 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GBG87560.1 - 2.1e-09 37.7 1.9 0.00048 20.4 0.3 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GBG87560.1 - 4.3e-09 36.6 1.3 0.0032 17.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GBG87560.1 - 0.49 10.4 9.5 2.1 8.3 0.8 2.7 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand NOA36 PF06524.12 GBG87560.1 - 3.8 6.7 12.4 6 6.1 12.4 1.3 1 0 0 1 1 1 0 NOA36 protein RT_RNaseH PF17917.1 GBG87561.1 - 4.9e-18 65.3 0.0 1.4e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87561.1 - 1.4e-09 37.9 0.0 4e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG87561.1 - 7.9e-09 35.2 1.5 1.8e-08 34.0 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG87561.1 - 4.4e-07 30.4 0.0 9.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87561.1 - 8.3e-05 23.2 0.0 0.00019 22.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG87561.1 - 0.00027 20.7 2.0 0.00056 19.7 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG87561.1 - 0.00043 20.1 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87561.1 - 0.007 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CHAT PF12770.7 GBG87562.1 - 7.3e-21 74.8 0.0 1.2e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 CHAT domain Asp_protease_2 PF13650.6 GBG87563.1 - 2.4e-06 28.1 0.0 5.5e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87563.1 - 2.2e-05 24.9 0.0 5.3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87563.1 - 0.00011 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87563.1 - 0.00017 21.4 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Endonuc-FokI_C PF09254.11 GBG87563.1 - 0.1 11.8 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal CHAT PF12770.7 GBG87564.1 - 5.2e-43 147.5 0.0 2.1e-20 73.3 0.0 2.5 2 0 0 2 2 2 2 CHAT domain HSP70 PF00012.20 GBG87567.1 - 3.3e-149 497.9 0.0 4.2e-149 497.5 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG87567.1 - 1.6e-07 30.5 0.4 1.7e-06 27.1 0.2 2.5 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG87567.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG87567.1 - 0.045 14.2 0.7 5.3 7.5 0.0 3.4 3 2 0 3 3 3 0 Cell division protein FtsA COR PF16095.5 GBG87569.1 - 6.3e-09 35.9 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 GBG87569.1 - 6.5e-06 26.4 0.0 4.5e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GBG87569.1 - 0.05 13.2 0.0 0.36 10.4 0.0 2.2 1 1 0 1 1 1 0 Ras family DUF659 PF04937.15 GBG87570.1 - 2e-22 79.7 0.0 3.2e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Lipoxygenase PF00305.19 GBG87573.1 - 1.8e-116 390.2 0.0 1.3e-114 384.1 0.0 2.3 2 0 0 2 2 2 2 Lipoxygenase rhaM PF05336.13 GBG87573.1 - 0.13 12.4 0.9 0.31 11.1 0.5 1.7 2 0 0 2 2 2 0 L-rhamnose mutarotase RVT_1 PF00078.27 GBG87575.1 - 9.5e-51 172.4 9.9 7.3e-30 104.1 0.1 4.4 4 0 0 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) PIF1 PF05970.14 GBG87575.1 - 1.2e-37 130.0 0.0 2e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase RT_RNaseH_2 PF17919.1 GBG87575.1 - 2.7e-37 126.8 0.0 4.5e-33 113.3 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87575.1 - 6.1e-28 97.2 1.5 8.7e-28 96.7 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87575.1 - 6e-19 67.9 0.1 1.3e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG87575.1 - 4.4e-07 30.1 7.5 0.024 14.9 0.1 4.4 3 0 0 3 3 3 2 Retrotransposon gag protein AAA_30 PF13604.6 GBG87575.1 - 1.3e-05 25.0 0.0 2.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain rve PF00665.26 GBG87575.1 - 0.0054 16.9 0.1 0.015 15.4 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG87575.1 - 0.0059 16.8 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger NIR_SIR PF01077.22 GBG87575.1 - 0.039 13.5 0.1 6.3 6.3 0.1 2.5 2 0 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain DUF2959 PF11172.8 GBG87575.1 - 0.11 12.6 2.8 0.16 12.1 0.8 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF2959) HIP1_clath_bdg PF16515.5 GBG87575.1 - 0.3 11.7 7.9 0.25 12.0 4.9 2.6 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4472 PF14739.6 GBG87575.1 - 0.68 10.7 6.6 2.4 9.0 0.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) UPF0449 PF15136.6 GBG87575.1 - 1.1 9.8 3.6 3 8.4 1.9 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 I_LWEQ PF01608.17 GBG87575.1 - 1.3 9.2 4.5 0.43 10.8 0.5 2.2 2 0 0 2 2 2 0 I/LWEQ domain Exonuc_VII_L PF02601.15 GBG87575.1 - 3 7.3 5.0 19 4.7 4.7 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 GBG87575.1 - 5.9 7.3 9.5 0.54 10.6 1.7 3.3 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HalOD2 PF18547.1 GBG87576.1 - 2.8e-06 27.1 0.0 29 4.7 0.0 15.5 1 0 0 1 1 1 1 Halobacterial output domain 2 OmpH PF03938.14 GBG87576.1 - 8.6 6.7 18.6 15 6.0 2.0 5.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) N6_N4_Mtase PF01555.18 GBG87577.1 - 0.00037 20.3 0.0 0.00046 20.0 0.0 1.5 1 1 0 1 1 1 1 DNA methylase gag-asp_proteas PF13975.6 GBG87578.1 - 0.00011 22.6 0.0 0.00027 21.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87578.1 - 0.00041 20.9 0.0 0.0011 19.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease VIR_N PF15912.5 GBG87578.1 - 0.28 10.7 3.9 0.43 10.1 3.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal RBM1CTR PF08081.11 GBG87578.1 - 5.7 7.1 13.7 3.3e+03 -1.8 13.7 2.9 1 1 0 1 1 1 0 RBM1CTR (NUC064) family BUD22 PF09073.10 GBG87579.1 - 7.5 5.8 59.0 11 5.3 59.0 1.3 1 0 0 1 1 1 0 BUD22 DUF3194 PF11419.8 GBG87580.1 - 0.049 14.0 1.3 0.092 13.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) RBD-FIP PF09457.10 GBG87580.1 - 0.16 11.9 2.6 0.22 11.5 0.2 2.5 3 0 0 3 3 3 0 FIP domain RVT_1 PF00078.27 GBG87581.1 - 1.4e-31 109.8 0.1 2.2e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87581.1 - 1.2e-30 105.9 0.0 2.5e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87581.1 - 1.9e-30 104.9 0.0 7.5e-15 54.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87581.1 - 0.00054 20.0 0.1 0.0012 18.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain REV PF00424.18 GBG87582.1 - 0.0065 16.5 1.7 0.73 9.9 0.1 2.5 2 0 0 2 2 2 2 REV protein (anti-repression trans-activator protein) RT_RNaseH_2 PF17919.1 GBG87584.1 - 3.1e-55 184.4 0.1 5.4e-30 103.4 0.2 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87584.1 - 4e-51 171.7 0.2 2.3e-27 95.4 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87584.1 - 5.8e-41 140.4 2.4 6e-29 101.1 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87584.1 - 9.7e-17 60.8 2.6 4.2e-15 55.6 0.5 3.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG87584.1 - 1.5e-08 34.8 0.0 5.2e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG87584.1 - 0.027 14.2 0.0 0.09 12.5 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Chromo PF00385.24 GBG87584.1 - 0.03 14.2 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG87585.1 - 3.7e-36 124.7 0.0 5.6e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87585.1 - 5.1e-24 84.2 0.0 1.3e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87585.1 - 2.2e-12 47.2 0.0 5e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4392 PF14336.6 GBG87585.1 - 0.0037 16.7 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) RasGEF_N PF00618.20 GBG87586.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 RasGEF N-terminal motif YjbH PF06082.11 GBG87586.1 - 0.083 11.7 1.2 0.11 11.2 1.2 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH RVT_1 PF00078.27 GBG87587.1 - 6.6e-14 52.0 0.0 1.6e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87587.1 - 1.1e-08 34.9 0.0 2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG87587.1 - 1.4e-07 31.7 0.0 3.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG87587.1 - 3.7e-05 24.3 0.0 9.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87587.1 - 0.00045 20.7 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG87587.1 - 0.0005 19.9 0.0 0.0019 18.0 0.0 1.9 2 0 0 2 2 2 1 Putative peptidase (DUF1758) DUF2052 PF09747.9 GBG87587.1 - 0.39 10.8 12.5 1.1 9.3 12.4 1.8 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AAA_11 PF13086.6 GBG87587.1 - 5.8 6.6 8.1 11 5.6 8.1 1.4 1 0 0 1 1 1 0 AAA domain DDE_Tnp_4 PF13359.6 GBG87588.1 - 6.6e-21 74.6 0.0 1.7e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87588.1 - 1.6e-09 37.7 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG87588.1 - 4.7e-05 23.1 0.1 0.11 12.2 0.0 2.8 2 0 0 2 2 2 2 Transposase DDE domain RT_RNaseH PF17917.1 GBG87588.1 - 0.00028 21.1 0.2 0.00067 19.9 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG87588.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Nop14 PF04147.12 GBG87588.1 - 1 7.5 33.4 2.1 6.4 33.4 1.5 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 GBG87588.1 - 1.3 9.0 35.5 3.5 7.6 35.5 1.7 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) NOA36 PF06524.12 GBG87588.1 - 1.7 7.9 20.8 4.5 6.5 20.8 1.7 1 0 0 1 1 1 0 NOA36 protein Retrotrans_gag PF03732.17 GBG87589.1 - 0.00011 22.4 0.2 0.00033 20.9 0.2 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein EutC PF05985.11 GBG87589.1 - 0.045 13.0 0.1 0.076 12.3 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) TolA_bind_tri PF16331.5 GBG87589.1 - 0.078 13.1 0.0 0.22 11.6 0.1 1.7 2 0 0 2 2 2 0 TolA binding protein trimerisation ATG16 PF08614.11 GBG87589.1 - 2.3 8.4 8.2 7.3 6.8 1.9 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SF3a60_bindingd PF12108.8 GBG87591.1 - 0.063 13.2 4.5 3.8 7.5 0.4 2.6 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Pkinase_Tyr PF07714.17 GBG87592.1 - 6.6e-10 38.7 0.0 1.1e-09 38.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87592.1 - 1.8e-08 34.1 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF659 PF04937.15 GBG87593.1 - 2.1e-31 108.8 0.1 4.3e-31 107.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DDE_Tnp_4 PF13359.6 GBG87594.1 - 4.9e-17 62.0 0.0 1.2e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87594.1 - 2.8e-08 33.6 0.0 4.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG87594.1 - 0.00037 20.2 0.0 0.0007 19.3 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG87595.1 - 4.4e-07 30.2 1.2 4.4e-07 30.2 1.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG87595.1 - 0.0083 16.4 1.2 0.0083 16.4 1.2 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF5476 PF17570.2 GBG87595.1 - 0.17 12.3 0.1 0.57 10.6 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5476) Myb_DNA-bind_5 PF13873.6 GBG87595.1 - 0.22 11.6 1.0 0.71 10.0 1.0 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain gag-asp_proteas PF13975.6 GBG87596.1 - 3.9e-07 30.5 0.1 9.6e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87596.1 - 3.9e-05 24.2 0.1 0.0001 22.9 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87596.1 - 0.00028 20.7 0.1 0.00042 20.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87596.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease cNMP_binding PF00027.29 GBG87596.1 - 0.14 12.2 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain RVT_1 PF00078.27 GBG87597.1 - 5.4e-26 91.5 0.1 8.6e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG87597.1 - 3.3 5.8 8.9 4.2 5.5 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2040 PF09745.9 GBG87600.1 - 8.6e-35 119.4 19.7 8.6e-35 119.4 19.7 3.3 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) MPS2 PF17060.5 GBG87600.1 - 4.9 6.3 11.9 8.3 5.6 11.9 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Casc1_N PF15927.5 GBG87602.1 - 0.1 12.3 27.6 0.35 10.5 13.7 2.1 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Phage_Gp23 PF10669.9 GBG87602.1 - 8.3 6.8 18.1 0.77 10.1 9.7 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) RVT_1 PF00078.27 GBG87603.1 - 0.099 12.1 0.1 0.22 11.0 0.0 1.5 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG87604.1 - 1.2e-26 93.7 0.0 2e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87604.1 - 4.2e-24 84.8 0.0 1.2e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87604.1 - 2.9e-20 72.2 0.0 1.3e-19 70.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87604.1 - 3.5e-18 65.5 0.6 1.4e-17 63.5 0.5 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG87604.1 - 1.1e-06 29.2 0.0 2.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87604.1 - 7.8e-06 26.4 0.0 1.7e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87604.1 - 5e-05 23.1 0.0 9.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87604.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG87604.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG87604.1 - 0.068 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Pkinase_Tyr PF07714.17 GBG87605.1 - 2.8e-36 125.1 0.0 4.9e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87605.1 - 5.4e-33 114.5 0.0 9.2e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH PF17917.1 GBG87605.1 - 1.1e-22 80.3 0.0 7.5e-22 77.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87605.1 - 1.9e-21 75.9 0.0 4.9e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87605.1 - 4.7e-18 65.0 0.3 9.7e-18 64.0 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87605.1 - 1.6e-17 63.8 0.0 3.8e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG87605.1 - 1.5e-05 24.6 0.0 3.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.23 GBG87605.1 - 0.00071 19.6 0.0 0.0023 17.9 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-H2C2 PF09337.10 GBG87605.1 - 0.0022 18.2 0.1 0.0053 17.0 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG87605.1 - 0.089 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein PQQ_3 PF13570.6 GBG87605.1 - 0.099 13.2 0.2 4.6 7.9 0.1 3.0 2 0 0 2 2 2 0 PQQ-like domain rve_3 PF13683.6 GBG87605.1 - 0.12 12.2 0.0 0.49 10.2 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 GBG87606.1 - 0.0011 19.4 0.4 0.0078 16.8 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87606.1 - 0.0052 17.4 0.1 0.042 14.5 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 GBG87606.1 - 0.11 12.6 1.9 0.21 11.7 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle AbLIM_anchor PF16182.5 GBG87606.1 - 0.27 11.0 4.2 0.58 9.9 4.2 1.5 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM Methyltransf_12 PF08242.12 GBG87606.1 - 2.7 8.8 4.8 40 5.0 0.2 3.2 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_60s PF00428.19 GBG87606.1 - 4.2 8.0 8.7 0.95 10.1 4.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein rve PF00665.26 GBG87608.1 - 3.1e-12 46.7 0.0 9.1e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain STOP PF05217.12 GBG87608.1 - 0.00099 19.4 2.0 0.00099 19.4 2.0 3.3 4 0 0 4 4 4 1 STOP protein PHINT_rpt PF14882.6 GBG87608.1 - 0.14 12.4 4.4 23 5.4 1.6 3.8 3 0 0 3 3 3 0 Phage-integrase repeat unit RPAP3_C PF13877.6 GBG87609.1 - 3.7e-22 78.7 0.0 8.4e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 GBG87609.1 - 6.7e-15 54.2 3.0 1.4e-05 24.6 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG87609.1 - 9.1e-11 41.0 7.3 0.00013 21.8 1.7 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG87609.1 - 0.01 15.5 0.4 14 5.5 0.3 3.3 2 1 1 3 3 3 0 TPR repeat TPR_8 PF13181.6 GBG87609.1 - 0.011 15.9 3.0 2.4 8.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GBG87609.1 - 0.018 15.2 2.1 0.068 13.3 2.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG87609.1 - 0.061 14.0 7.5 2.1 9.1 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat YpjP PF14005.6 GBG87609.1 - 0.088 12.9 2.0 0.2 11.7 2.0 1.5 1 0 0 1 1 1 0 YpjP-like protein TPR_19 PF14559.6 GBG87609.1 - 0.31 11.6 2.4 3.1 8.4 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG87609.1 - 2.3 8.6 11.3 1.1 9.5 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Tfb2 PF03849.14 GBG87610.1 - 1.2e-103 346.8 0.0 1.4e-103 346.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 GBG87610.1 - 1e-20 73.9 0.2 2.2e-20 72.8 0.2 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 GBG87610.1 - 0.00027 21.1 0.1 0.0023 18.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Telomere_reg-2 PF10193.9 GBG87612.1 - 2.6e-16 60.0 0.0 8.8e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein RT_RNaseH_2 PF17919.1 GBG87613.1 - 3.2e-28 97.7 0.0 7.4e-28 96.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87613.1 - 1.5e-25 89.5 0.0 3.2e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87613.1 - 3e-10 40.0 0.1 5.1e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5085 PF16895.5 GBG87613.1 - 0.014 15.7 0.1 0.03 14.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5085) RP-C_C PF11800.8 GBG87613.1 - 0.39 10.8 11.3 2.1 8.4 0.1 2.6 2 0 0 2 2 2 0 Replication protein C C-terminal region Nop14 PF04147.12 GBG87613.1 - 3.2 5.8 21.3 5.5 5.1 21.3 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG87613.1 - 4.3 6.6 23.9 7.5 5.8 23.9 1.3 1 0 0 1 1 1 0 BUD22 Pkinase_Tyr PF07714.17 GBG87614.1 - 4.3e-39 134.3 0.0 6.7e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87614.1 - 7.6e-34 117.3 0.0 1.6e-33 116.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG87614.1 - 1.1e-05 25.5 0.1 4.2e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family NHL PF01436.21 GBG87614.1 - 0.015 15.3 0.1 13 6.0 0.0 3.3 3 0 0 3 3 3 0 NHL repeat SKG6 PF08693.10 GBG87614.1 - 0.14 11.6 4.6 0.38 10.2 4.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 GBG87614.1 - 0.17 10.6 0.0 0.41 9.3 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase MF_alpha PF04648.12 GBG87614.1 - 1.2 9.5 5.4 11 6.5 1.7 2.7 2 0 0 2 2 2 0 Yeast mating factor alpha hormone Myb_DNA-bind_4 PF13837.6 GBG87616.1 - 7.9e-05 23.0 0.4 0.00023 21.5 0.2 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG87616.1 - 0.0016 18.4 0.7 0.0016 18.4 0.7 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 GBG87617.1 - 0.00044 20.5 0.6 0.011 16.0 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein CorA PF01544.18 GBG87617.1 - 0.0056 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Acid_PPase PF12689.7 GBG87617.1 - 0.024 14.5 0.7 0.36 10.7 0.2 2.2 2 0 0 2 2 2 0 Acid Phosphatase TolA_bind_tri PF16331.5 GBG87617.1 - 1 9.5 8.2 2.1 8.5 1.1 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation SlyX PF04102.12 GBG87617.1 - 7.7 7.2 8.4 2.6 8.7 1.7 2.9 2 1 1 3 3 3 0 SlyX Pkinase PF00069.25 GBG87618.1 - 6.6e-37 127.3 0.0 1e-36 126.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG87618.1 - 2.8e-36 125.2 0.0 6.9e-36 123.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG87618.1 - 0.00095 19.2 0.1 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PRIMA1 PF16101.5 GBG87618.1 - 0.065 13.3 0.1 0.065 13.3 0.1 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pkinase_fungal PF17667.1 GBG87618.1 - 0.069 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Cadherin_C_2 PF16492.5 GBG87618.1 - 0.11 13.3 0.0 0.26 12.1 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RT_RNaseH_2 PF17919.1 GBG87620.1 - 2.2e-08 34.1 0.0 5.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87620.1 - 5.1e-06 26.7 0.0 1.3e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG87621.1 - 3e-29 101.9 0.0 4.9e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87621.1 - 7e-07 28.9 0.1 1.6e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region 3HCDH_N PF02737.18 GBG87621.1 - 0.54 10.1 0.0 0.54 10.1 0.0 2.2 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SDA1 PF05285.12 GBG87621.1 - 6.3 6.1 23.0 11 5.3 23.0 1.4 1 0 0 1 1 1 0 SDA1 Histone PF00125.24 GBG87622.1 - 1.5e-13 51.2 0.1 1.5e-13 51.2 0.1 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Hpt PF01627.23 GBG87623.1 - 0.0025 18.1 0.2 0.011 16.0 0.0 2.1 3 0 0 3 3 3 1 Hpt domain Retrotrans_gag PF03732.17 GBG87624.1 - 0.00067 19.9 2.4 0.0023 18.2 0.1 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2781 PF10914.8 GBG87624.1 - 0.13 12.7 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) LAP1C PF05609.12 GBG87625.1 - 3.7 6.5 13.6 4.7 6.2 13.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) LMBR1 PF04791.16 GBG87625.1 - 6.8 5.5 8.1 8.6 5.1 8.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RVT_1 PF00078.27 GBG87626.1 - 1.2e-101 338.8 1.9 2.2e-31 109.1 0.0 5.3 5 0 0 5 5 5 4 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87626.1 - 7.1e-68 224.9 0.0 3.2e-28 97.7 0.0 3.9 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87626.1 - 1.3e-38 131.5 0.0 1.2e-16 60.8 0.0 4.3 4 0 0 4 4 3 3 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87626.1 - 2.1e-13 50.5 0.0 5.5e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG87626.1 - 3.4e-06 27.3 0.6 0.19 12.0 0.0 4.3 3 0 0 3 3 3 2 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG87626.1 - 4.9e-06 27.0 0.0 3.2e-05 24.4 0.0 2.5 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87626.1 - 1.7e-05 25.4 0.0 5.1e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87626.1 - 0.00071 19.4 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1564 PF07600.11 GBG87626.1 - 0.0027 17.4 0.0 0.014 15.1 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) Asp_protease PF09668.10 GBG87626.1 - 0.0042 16.9 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF5320 PF17253.2 GBG87626.1 - 9.7 7.3 12.0 9.8 7.3 2.3 3.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) RT_RNaseH_2 PF17919.1 GBG87627.1 - 5.5e-32 109.8 0.1 1e-31 108.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87627.1 - 6.1e-29 100.4 0.1 1.1e-28 99.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87627.1 - 5e-16 58.6 1.5 7.3e-16 58.0 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG87627.1 - 1.1e-13 51.4 0.0 3.6e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG87627.1 - 1.1e-09 38.1 0.0 2.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG87627.1 - 0.077 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger rve PF00665.26 GBG87628.1 - 0.054 13.7 0.4 0.31 11.2 0.4 2.2 1 1 0 1 1 1 0 Integrase core domain Chromo PF00385.24 GBG87628.1 - 0.095 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG87629.1 - 0.0022 17.5 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG87629.1 - 1.7 8.0 19.9 2 7.7 19.9 1.1 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.10 GBG87629.1 - 2.7 8.3 10.4 3.8 7.8 10.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 GBG87629.1 - 3.1 5.9 20.8 3.8 5.6 20.8 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG87629.1 - 3.3 5.9 16.6 4.1 5.6 16.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BTB PF00651.31 GBG87630.1 - 1.9e-12 47.4 0.0 4.5e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain TH1 PF04858.13 GBG87631.1 - 0.22 10.1 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 TH1 protein DUF4637 PF15470.6 GBG87632.1 - 0.047 13.4 1.4 0.056 13.2 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Asp_protease_2 PF13650.6 GBG87634.1 - 8e-07 29.6 0.0 2.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87634.1 - 1.3e-06 28.9 0.0 3.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87634.1 - 5.9e-06 26.1 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87634.1 - 0.00054 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG87634.1 - 0.0031 17.4 0.4 0.0097 15.8 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG87634.1 - 0.13 12.5 0.2 0.74 10.0 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain Retrotrans_gag PF03732.17 GBG87635.1 - 0.0003 21.0 1.1 0.00099 19.3 0.2 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein Sclerostin PF05463.11 GBG87635.1 - 0.17 11.6 1.4 1.6 8.4 0.1 2.1 1 1 1 2 2 2 0 Sclerostin (SOST) DUF4360 PF14273.6 GBG87636.1 - 1.8e-37 129.0 0.2 2e-37 128.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG87639.1 - 1.2e-43 149.1 0.0 1.4e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) zf-CCHC PF00098.23 GBG87640.1 - 2.1e-07 30.7 2.8 3.7e-07 29.9 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG87640.1 - 0.037 13.8 1.9 0.061 13.2 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG87643.1 - 5.2e-27 94.5 0.0 9.4e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87643.1 - 2.1e-12 47.1 0.0 4.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG87643.1 - 0.0037 16.9 0.1 1 9.0 0.0 3.2 3 0 0 3 3 3 1 Transposase DDE domain DUF659 PF04937.15 GBG87644.1 - 1.9e-05 24.5 0.0 3.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) O-antigen_lig PF13425.6 GBG87645.1 - 1.4 7.6 2.0 2.4 6.8 2.0 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CemA PF03040.14 GBG87645.1 - 1.9 8.4 5.6 6.1 6.7 5.6 1.8 1 0 0 1 1 1 0 CemA family V_ATPase_I PF01496.19 GBG87645.1 - 9.7 4.0 10.6 0.46 8.3 2.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DDE_Tnp_4 PF13359.6 GBG87647.1 - 7.3e-28 97.2 0.0 1.3e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87647.1 - 1e-11 44.9 0.0 1.6e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG87647.1 - 0.056 13.1 0.0 11 5.6 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain SDA1 PF05285.12 GBG87649.1 - 0.21 11.0 14.5 0.26 10.7 14.5 1.0 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG87649.1 - 8.5 4.5 9.7 10 4.3 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG87649.1 - 9.3 4.3 14.1 11 4.1 14.1 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG87649.1 - 9.5 5.4 13.7 12 5.1 13.7 1.1 1 0 0 1 1 1 0 BUD22 DUF5132 PF17195.4 GBG87651.1 - 0.019 15.1 1.6 6.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Neur_chan_memb PF02932.16 GBG87652.1 - 9.3 6.2 13.0 12 5.9 1.2 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Myb_DNA-bind_4 PF13837.6 GBG87653.1 - 1.3e-06 28.7 2.1 2.2e-06 28.0 2.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG87653.1 - 0.033 14.5 0.4 0.067 13.5 0.4 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVT_1 PF00078.27 GBG87654.1 - 1.8e-34 119.2 0.0 2.8e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87654.1 - 4.5e-07 29.7 0.0 9.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87654.1 - 7.4e-06 26.5 0.0 1.6e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87654.1 - 0.0002 21.9 0.1 0.0015 19.1 0.0 2.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG87654.1 - 0.0019 18.0 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG87654.1 - 0.0019 18.0 0.0 0.0072 16.1 0.0 1.9 2 1 0 2 2 2 1 Aspartyl protease DUF1690 PF07956.11 GBG87654.1 - 0.19 12.2 7.9 0.47 10.9 7.9 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) RT_RNaseH_2 PF17919.1 GBG87655.1 - 1.9e-30 104.8 0.0 5.2e-29 100.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87655.1 - 2.5e-29 101.7 0.1 1.3e-27 96.2 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87655.1 - 2e-18 66.7 0.0 6.9e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG87655.1 - 1.5e-17 63.5 0.3 3.2e-17 62.4 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG87655.1 - 0.06 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG87655.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG87656.1 - 1.8e-27 96.3 0.0 2.8e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87656.1 - 2.6e-23 81.9 0.0 5.6e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87656.1 - 4.4e-21 75.1 0.0 7.9e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87656.1 - 9.8e-14 51.2 2.4 1.1e-13 51.0 0.6 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG87656.1 - 1e-07 32.5 0.0 2.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87656.1 - 1.7e-07 31.7 0.0 3.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87656.1 - 2.6e-07 30.5 0.0 7.1e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease rve PF00665.26 GBG87656.1 - 3.7e-05 23.9 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG87656.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG87656.1 - 0.047 13.9 0.2 0.14 12.4 0.2 1.9 1 0 0 1 1 1 0 H2C2 zinc finger NRDE-2 PF08424.10 GBG87657.1 - 0.092 11.9 0.9 0.098 11.8 0.9 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF4061 PF13270.6 GBG87657.1 - 0.43 10.9 3.2 0.24 11.7 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Selenoprotein_S PF06936.11 GBG87657.1 - 1.4 8.7 3.8 2.7 7.8 3.8 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF659 PF04937.15 GBG87658.1 - 1.1e-14 54.5 0.0 2.2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG87659.1 - 0.032 14.6 0.9 0.082 13.3 0.1 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG87660.1 - 4.6e-12 46.0 0.0 9.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87660.1 - 2.3e-08 33.7 0.0 5.5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG87660.1 - 3.7e-08 33.3 0.0 1.5e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87660.1 - 3e-06 26.9 0.4 0.049 13.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87660.1 - 4.5e-06 26.9 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4607 PF15380.6 GBG87661.1 - 0.013 15.0 1.0 0.019 14.4 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) RT_RNaseH_2 PF17919.1 GBG87663.1 - 1.9e-29 101.7 0.0 4.6e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87663.1 - 2.9e-25 89.1 0.0 6.7e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87663.1 - 1.7e-22 79.6 0.1 4.4e-22 78.4 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87663.1 - 9.5e-14 51.2 0.2 2.3e-13 50.0 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF659 PF04937.15 GBG87663.1 - 8.9e-11 41.9 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-H2C2 PF09337.10 GBG87663.1 - 0.00093 19.4 0.0 0.0027 17.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger GCIP PF13324.6 GBG87663.1 - 2.9 7.4 3.8 5.9 6.4 3.8 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RVT_1 PF00078.27 GBG87665.1 - 2e-31 109.2 0.1 2.7e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87665.1 - 1.1e-10 41.5 0.0 2.5e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87665.1 - 0.002 18.4 0.0 0.0042 17.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG87665.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 RVT_1 PF00078.27 GBG87667.1 - 0.0011 18.6 0.1 0.062 12.8 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) SNARE PF05739.19 GBG87668.1 - 2.6e-14 52.9 3.1 2.6e-14 52.9 3.1 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 GBG87668.1 - 0.0069 16.1 15.9 0.048 13.3 0.3 2.8 3 0 0 3 3 3 2 Syntaxin Synaptobrevin PF00957.21 GBG87668.1 - 0.15 11.9 10.6 0.019 14.7 6.4 1.7 2 0 0 2 2 2 0 Synaptobrevin CCDC-167 PF15188.6 GBG87668.1 - 0.38 11.1 8.1 2.8 8.3 0.1 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TMCO5 PF14992.6 GBG87668.1 - 0.45 10.1 10.2 1.2 8.7 10.2 1.6 1 1 0 1 1 1 0 TMCO5 family DUF3675 PF12428.8 GBG87668.1 - 0.75 10.4 3.0 0.78 10.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Tweety PF04906.13 GBG87668.1 - 1.1 7.9 4.3 0.72 8.4 0.7 2.0 2 0 0 2 2 2 0 Tweety Syntaxin_2 PF14523.6 GBG87668.1 - 2.6 8.5 14.1 0.32 11.4 7.2 2.5 2 1 0 2 2 2 0 Syntaxin-like protein DUF659 PF04937.15 GBG87669.1 - 1.4e-29 102.9 0.0 2.7e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87669.1 - 9.6e-07 28.5 0.3 2.2e-06 27.4 0.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Presenilin PF01080.17 GBG87669.1 - 7 5.3 17.6 9.8 4.8 17.6 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_3_Rpc31 PF11705.8 GBG87670.1 - 0.016 15.5 57.3 0.29 11.3 13.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Prothymosin PF03247.14 GBG87670.1 - 0.029 14.8 67.9 0.2 12.2 36.6 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family Spem1 PF15670.5 GBG87670.1 - 0.17 11.4 18.8 0.31 10.6 18.8 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 GAGA_bind PF06217.12 GBG87670.1 - 0.81 9.9 19.0 1.1 9.5 19.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SRP-alpha_N PF04086.13 GBG87670.1 - 2.1 8.2 34.0 2.7 7.8 34.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4551 PF15087.6 GBG87670.1 - 6.3 5.5 12.0 6.8 5.4 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOBP PF15279.6 GBG87670.1 - 7.4 7.1 8.2 9.1 6.8 8.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RB_A PF01858.17 GBG87671.1 - 1.1e-54 185.3 0.3 4.4e-54 183.3 0.0 2.0 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 GBG87671.1 - 8.3e-36 122.9 2.2 1.7e-35 121.9 2.2 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 GBG87671.1 - 1.5e-19 69.9 0.1 1.3e-18 66.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) RPA_C PF08784.11 GBG87671.1 - 0.19 12.4 2.5 0.25 12.0 0.1 2.4 2 0 0 2 2 2 0 Replication protein A C terminal RT_RNaseH_2 PF17919.1 GBG87673.1 - 2.1e-31 107.9 0.1 4.1e-31 107.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87673.1 - 1e-29 103.7 0.0 1.8e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87673.1 - 2.1e-18 66.6 0.0 5e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Spectrin PF00435.21 GBG87673.1 - 0.96 10.0 2.9 0.73 10.3 0.3 2.2 2 0 0 2 2 2 0 Spectrin repeat Asp_protease_2 PF13650.6 GBG87674.1 - 1.7e-06 28.6 0.1 3.7e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87674.1 - 2.5e-05 24.8 0.1 6.1e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87674.1 - 0.00064 19.5 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG87674.1 - 0.0011 19.2 0.0 0.69 10.2 0.0 2.7 2 0 0 2 2 2 2 Retrotransposon gag protein zf-CCHC PF00098.23 GBG87674.1 - 0.038 14.1 2.7 0.063 13.4 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG87674.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG87674.1 - 0.16 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Polyketide_cyc PF03364.20 GBG87674.1 - 0.5 10.6 2.7 2.4 8.4 0.2 2.7 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport tRNA-synt_1_2 PF13603.6 GBG87675.1 - 4.6 6.7 6.3 7.4 6.0 2.3 2.6 1 1 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 Integrase_H2C2 PF17921.1 GBG87676.1 - 3.7e-18 65.4 0.3 8.2e-18 64.3 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87676.1 - 4.9e-15 55.8 0.1 1.3e-14 54.4 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG87676.1 - 3.9e-13 49.6 1.2 7.5e-13 48.7 1.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87676.1 - 7.5e-06 25.9 0.2 1.4e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG87676.1 - 0.0026 17.9 0.0 0.0076 16.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_4 PF14392.6 GBG87676.1 - 0.035 13.8 1.0 0.25 11.1 0.1 2.8 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG87676.1 - 0.12 12.2 0.4 0.25 11.2 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG87676.1 - 0.13 12.4 4.1 0.26 11.4 4.1 1.5 1 0 0 1 1 1 0 Zinc knuckle GTP-bdg_M PF16360.5 GBG87677.1 - 0.00053 20.5 4.0 0.0019 18.7 4.0 1.9 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region zf-CCHC_3 PF13917.6 GBG87677.1 - 0.0032 17.4 1.7 0.007 16.3 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle LegC3_N PF18654.1 GBG87677.1 - 0.028 13.7 1.1 0.036 13.3 1.1 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain SbcD_C PF12320.8 GBG87677.1 - 0.18 12.1 2.5 0.31 11.4 2.5 1.4 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Retrotrans_gag PF03732.17 GBG87679.1 - 0.004 17.4 0.1 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein CorA PF01544.18 GBG87679.1 - 0.024 14.0 0.1 0.071 12.4 0.1 1.8 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cnl2_NKP2 PF09447.10 GBG87679.1 - 0.053 13.7 0.1 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 Cnl2/NKP2 family protein DDRGK PF09756.9 GBG87679.1 - 2.5 7.7 11.5 5.6 6.5 11.5 1.5 1 0 0 1 1 1 0 DDRGK domain rve PF00665.26 GBG87680.1 - 1.3e-13 51.1 0.2 2.3e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG87680.1 - 0.07 12.8 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG87681.1 - 2.4e-34 118.8 0.1 4.7e-34 117.8 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87681.1 - 6.8e-30 103.1 0.0 1.7e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87681.1 - 4.9e-29 100.7 0.1 1e-28 99.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AAA_6 PF12774.7 GBG87683.1 - 7.1e-144 478.8 0.0 5.1e-142 472.6 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 GBG87683.1 - 2.7e-73 245.3 0.7 1.3e-67 226.8 0.1 3.6 3 0 0 3 3 3 3 P-loop containing dynein motor region DHC_N2 PF08393.13 GBG87683.1 - 9.1e-37 127.1 0.1 5.3e-36 124.6 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_lid_1 PF17857.1 GBG87683.1 - 9.2e-27 93.2 0.1 3.5e-26 91.3 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GBG87683.1 - 1.8e-23 83.0 0.0 7.3e-11 42.2 0.0 5.7 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 GBG87683.1 - 6.7e-23 81.2 1.8 7.7e-23 81.0 0.4 1.9 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 GBG87683.1 - 7.1e-09 36.2 0.1 0.01 16.3 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG87683.1 - 4.4e-07 30.4 0.0 0.31 11.4 0.0 4.0 3 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 GBG87683.1 - 4.8e-06 27.1 0.0 0.28 11.7 0.0 3.7 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 GBG87683.1 - 9.6e-06 25.4 1.5 2 8.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 GBG87683.1 - 6.3e-05 23.3 0.1 0.78 10.2 0.0 3.8 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 GBG87683.1 - 7.8e-05 23.0 0.1 2.1 8.6 0.0 3.9 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 GBG87683.1 - 0.00016 21.6 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 GBG87683.1 - 0.0003 20.9 0.0 5.3 7.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 GBG87683.1 - 0.0007 19.6 0.9 4.1 7.4 0.0 3.6 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GBG87683.1 - 0.0015 19.1 0.0 0.055 14.0 0.0 2.8 3 0 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.26 GBG87683.1 - 0.0016 18.2 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 GBG87683.1 - 0.0018 18.6 0.1 13 6.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 GBG87683.1 - 0.0038 17.3 0.0 17 5.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 GBG87683.1 - 0.015 15.6 0.0 4.3 7.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 GBG87683.1 - 0.019 14.9 0.0 0.54 10.1 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase PhoH PF02562.16 GBG87683.1 - 0.019 14.4 0.2 22 4.4 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein NB-ARC PF00931.22 GBG87683.1 - 0.027 13.7 0.0 5.3 6.2 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 GBG87683.1 - 0.032 14.0 0.0 13 5.5 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 GBG87683.1 - 0.048 13.4 0.1 0.82 9.4 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF3512 PF12024.8 GBG87683.1 - 0.052 13.0 0.1 0.097 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) ATPase_2 PF01637.18 GBG87683.1 - 0.053 13.4 0.0 1.1 9.1 0.0 2.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GBG87683.1 - 0.06 13.3 2.0 14 5.6 0.3 3.5 3 0 0 3 3 3 0 NACHT domain dNK PF01712.19 GBG87683.1 - 0.087 12.7 0.4 11 5.8 0.0 3.4 3 0 0 3 3 3 0 Deoxynucleoside kinase Sigma54_activ_2 PF14532.6 GBG87683.1 - 0.13 12.4 0.0 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Roc PF08477.13 GBG87683.1 - 0.14 12.4 0.1 4.8 7.4 0.0 3.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 GBG87683.1 - 0.16 11.2 0.0 4 6.7 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin DUF815 PF05673.13 GBG87683.1 - 0.32 10.1 2.2 13 4.9 0.0 3.1 4 0 0 4 4 3 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 GBG87683.1 - 0.36 10.4 1.0 11 5.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 GBG87683.1 - 4.9 7.2 6.2 9.8 6.2 0.0 3.8 5 0 0 5 5 4 0 Helicase HerA, central domain RT_RNaseH_2 PF17919.1 GBG87684.1 - 3.6e-31 107.2 0.0 1e-30 105.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87684.1 - 7.4e-29 100.1 0.0 1.9e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87684.1 - 1.6e-20 73.6 0.0 3.3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG87684.1 - 0.1 12.9 0.0 0.37 11.1 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Snapin_Pallidin PF14712.6 GBG87684.1 - 6.5 7.2 7.7 0.87 10.1 0.2 3.3 2 1 2 4 4 4 0 Snapin/Pallidin Vasculin PF15337.6 GBG87685.1 - 0.015 16.2 0.1 1.2 10.0 0.0 2.5 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 MT PF12777.7 GBG87686.1 - 9.2e-97 324.1 5.7 9.2e-97 324.1 5.7 2.0 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 GBG87686.1 - 5e-94 314.5 0.0 9.2e-94 313.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 GBG87686.1 - 3e-86 289.4 3.6 1.6e-53 181.9 2.1 2.9 3 0 0 3 3 3 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 GBG87686.1 - 4.2e-84 281.1 1.5 4.2e-84 281.1 1.5 3.0 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 GBG87686.1 - 7.8e-45 152.6 0.0 3e-44 150.7 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GBG87686.1 - 6.3e-37 126.3 0.0 4.4e-35 120.4 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain RT_RNaseH PF17917.1 GBG87686.1 - 2e-30 105.2 0.1 1.2e-29 102.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87686.1 - 4.1e-30 105.0 0.0 1e-29 103.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87686.1 - 4.2e-30 103.7 0.0 2.3e-29 101.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87686.1 - 5.3e-18 64.9 0.6 1.2e-17 63.7 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87686.1 - 1.4e-17 64.0 0.0 5.1e-17 62.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG87686.1 - 0.063 13.5 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger AAA_5 PF07728.14 GBG87686.1 - 0.12 12.4 0.0 0.49 10.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pro-MCH PF05824.12 GBG87687.1 - 2.9 7.9 0.0 2.9 7.9 0.0 3.8 4 1 1 5 5 5 0 Pro-melanin-concentrating hormone (Pro-MCH) LIN37 PF15306.6 GBG87688.1 - 4.8e-09 36.6 2.1 4.3e-07 30.3 2.1 2.2 1 1 0 1 1 1 1 LIN37 NYN PF01936.18 GBG87691.1 - 4.9e-25 88.7 0.0 8.8e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 GBG87691.1 - 5.5e-17 61.3 0.2 2.9e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 OST-HTH/LOTUS domain Arabinose_trans PF04602.12 GBG87691.1 - 1.3 7.8 5.4 2 7.2 5.4 1.2 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein CAMSAP_CKK PF08683.11 GBG87692.1 - 8.3e-18 64.7 0.0 1.5e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 GBG87692.1 - 5.4e-07 29.4 0.0 3.5e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 CAMSAP CH domain Myb_DNA-bind_4 PF13837.6 GBG87692.1 - 3.1e-05 24.3 0.2 8.6e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CH PF00307.31 GBG87692.1 - 6.7e-05 23.0 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Myb_DNA-bind_5 PF13873.6 GBG87692.1 - 0.0027 17.8 0.1 0.0063 16.6 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain FAD_binding_1 PF00667.20 GBG87695.1 - 4.2e-67 226.0 0.0 6.5e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GBG87695.1 - 1.4e-28 99.9 1.9 2.4e-28 99.1 0.2 2.4 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 GBG87695.1 - 7.2e-14 52.4 0.0 2.8e-12 47.2 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain HUN PF08729.10 GBG87696.1 - 2.5e-13 49.8 2.2 6e-13 48.6 2.2 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.6 GBG87696.1 - 8.5e-05 22.4 3.7 0.00036 20.3 3.7 2.1 1 1 0 1 1 1 1 Ubinuclein conserved middle domain Myb_DNA-bind_4 PF13837.6 GBG87697.1 - 0.00021 21.6 0.8 0.00021 21.6 0.8 1.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain DUF2057 PF09829.9 GBG87697.1 - 0.031 14.4 0.2 0.065 13.4 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Myb_DNA-bind_5 PF13873.6 GBG87697.1 - 0.059 13.4 1.2 0.079 13.0 0.1 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain WHIM1 PF15612.6 GBG87697.1 - 0.093 12.3 0.1 21 4.8 0.0 2.5 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 UPF0172 PF03665.13 GBG87698.1 - 3.6e-40 138.1 0.0 4e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 GBG87698.1 - 0.029 14.4 0.1 0.24 11.4 0.1 2.0 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-bind_4 PF13837.6 GBG87699.1 - 0.00026 21.3 0.6 0.00052 20.3 0.2 1.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain DUF4360 PF14273.6 GBG87700.1 - 8.2e-41 139.8 0.8 9.2e-41 139.6 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG87701.1 - 4e-45 153.9 0.2 4.6e-45 153.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DDE_Tnp_4 PF13359.6 GBG87703.1 - 1.2e-19 70.5 0.0 1.6e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87703.1 - 3.9e-09 36.4 0.0 6.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein TMEM108 PF15759.5 GBG87704.1 - 0.5 9.3 4.1 0.12 11.4 1.1 1.4 2 0 0 2 2 2 0 TMEM108 family DUF4360 PF14273.6 GBG87706.1 - 2.5e-38 131.7 1.8 2.8e-38 131.5 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) zf-CCHC PF00098.23 GBG87707.1 - 0.1 12.7 1.4 0.23 11.6 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG87708.1 - 2.6e-05 24.2 0.1 4.6e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG87708.1 - 0.0063 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 H2C2 zinc finger CDC45 PF02724.14 GBG87708.1 - 8.8 4.5 8.8 11 4.2 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Hexapep PF00132.24 GBG87709.1 - 0.026 14.3 3.4 0.43 10.4 0.1 3.4 3 0 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) DUF659 PF04937.15 GBG87710.1 - 1.3e-26 93.3 0.1 2e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG87711.1 - 4.1e-26 90.9 0.0 6.6e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87711.1 - 7.1e-23 80.9 0.0 1.1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87711.1 - 1.8e-13 50.5 0.0 2.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C48 PF02902.19 GBG87714.1 - 5.4e-20 72.2 0.0 9e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF572 PF04502.13 GBG87718.1 - 1 8.9 14.0 1.4 8.5 14.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4360 PF14273.6 GBG87719.1 - 1.1e-45 155.7 0.0 1.9e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF775 PF05603.12 GBG87719.1 - 0.41 10.2 1.9 0.85 9.1 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF3584 PF12128.8 GBG87719.1 - 4.3 4.7 19.3 5.6 4.3 19.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RT_RNaseH PF17917.1 GBG87720.1 - 6.4e-17 61.8 0.0 1.8e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87720.1 - 3.1e-15 56.0 0.0 8.2e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87720.1 - 6.9e-12 45.3 0.0 2.2e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG87720.1 - 7.4e-08 32.8 0.0 2e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87720.1 - 0.00042 20.9 0.0 0.0012 19.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87720.1 - 0.044 13.6 0.7 0.082 12.7 0.7 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG87720.1 - 0.08 13.3 0.0 0.29 11.5 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG87720.1 - 0.15 11.5 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) U79_P34 PF03064.16 GBG87720.1 - 2.7 7.3 12.2 3.5 6.9 10.9 1.8 2 0 0 2 2 2 0 HSV U79 / HCMV P34 USP8_interact PF08941.10 GBG87722.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 USP8 interacting DUF659 PF04937.15 GBG87723.1 - 6.7e-18 65.0 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Rho_N PF07498.12 GBG87724.1 - 0.00027 20.8 0.6 0.0006 19.7 0.6 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain ALS2CR11 PF15729.5 GBG87724.1 - 0.36 9.9 10.6 0.56 9.3 10.6 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 Cwf_Cwc_15 PF04889.12 GBG87724.1 - 7 6.3 24.1 1 9.1 19.5 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein AUDH_Cupin PF18637.1 GBG87726.1 - 0.019 15.0 0.9 5.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain DotD PF16816.5 GBG87726.1 - 0.15 12.0 0.5 49 3.9 0.0 4.1 2 1 2 5 5 5 0 DotD protein Peptidase_S49_N PF08496.10 GBG87727.1 - 0.17 11.9 2.3 0.47 10.5 2.3 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase_Tyr PF07714.17 GBG87731.1 - 1.7e-38 132.4 0.0 6.7e-38 130.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87731.1 - 1.6e-35 122.7 0.0 2.4e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG87731.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ_3 PF13570.6 GBG87731.1 - 1.1 9.8 7.3 0.46 11.1 0.5 3.3 3 0 0 3 3 3 0 PQQ-like domain Dimer_Tnp_hAT PF05699.14 GBG87732.1 - 0.036 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG87734.1 - 6.8e-13 48.7 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) VHP PF02209.19 GBG87734.1 - 0.015 15.4 0.4 0.031 14.3 0.0 1.7 2 0 0 2 2 2 0 Villin headpiece domain Pkinase_Tyr PF07714.17 GBG87736.1 - 4.4e-39 134.3 0.0 1.5e-38 132.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87736.1 - 1.5e-34 119.6 0.0 2.1e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG87736.1 - 0.04 13.8 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ_3 PF13570.6 GBG87736.1 - 8.8 7.0 7.4 6.4 7.4 1.1 3.4 3 0 0 3 3 3 0 PQQ-like domain Pkinase_Tyr PF07714.17 GBG87737.1 - 1.1e-36 126.5 0.0 4.3e-36 124.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87737.1 - 8.2e-35 120.4 0.0 1.4e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG87737.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GBG87740.1 - 5.7e-40 137.2 0.0 2.1e-39 135.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87740.1 - 2e-38 132.3 0.0 2.9e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG87740.1 - 0.041 13.8 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 GBG87741.1 - 3.8e-19 68.6 0.0 8.3e-14 51.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87741.1 - 2.2e-17 63.3 0.0 3.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87741.1 - 4.9e-14 52.2 0.0 4.9e-14 52.2 0.0 2.6 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG87741.1 - 8e-12 45.4 0.0 2.7e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG87741.1 - 3.8e-09 36.8 0.0 1.5e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG87741.1 - 7e-09 35.5 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG87741.1 - 1.8e-05 24.8 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG87741.1 - 0.076 13.7 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Pkinase_Tyr PF07714.17 GBG87742.1 - 3.7e-39 134.6 0.0 1.4e-38 132.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG87742.1 - 3.2e-36 125.0 0.0 5e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG87742.1 - 0.037 13.9 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ_3 PF13570.6 GBG87742.1 - 1.1 9.8 3.1 3.2 8.4 0.4 3.0 3 0 0 3 3 3 0 PQQ-like domain RT_RNaseH PF17917.1 GBG87743.1 - 9.5e-45 151.2 0.0 7.5e-21 74.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87743.1 - 2e-42 143.3 0.0 9.5e-20 70.5 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87743.1 - 8.3e-29 99.5 1.5 1.6e-14 53.8 0.1 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG87743.1 - 1.1e-14 54.7 0.0 2.8e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG87743.1 - 4.3e-10 39.5 0.0 8.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG87743.1 - 1.9e-07 31.2 0.0 0.0026 17.9 0.0 2.6 2 0 0 2 2 2 2 H2C2 zinc finger Drf_GBD PF06371.13 GBG87743.1 - 0.04 13.5 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain PilM PF07419.12 GBG87743.1 - 0.15 12.3 0.0 22 5.2 0.0 2.4 2 0 0 2 2 2 0 PilM CcdA PF07362.12 GBG87743.1 - 0.22 12.0 2.6 12 6.4 0.1 2.7 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Cwf_Cwc_15 PF04889.12 GBG87744.1 - 0.016 14.9 13.6 0.019 14.7 13.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SEN1_N PF12726.7 GBG87744.1 - 0.25 9.5 0.3 0.27 9.4 0.3 1.1 1 0 0 1 1 1 0 SEN1 N terminal SDA1 PF05285.12 GBG87744.1 - 1.1 8.6 12.7 1.2 8.5 12.7 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG87744.1 - 7.3 5.1 17.1 10 4.6 17.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Collagen PF01391.18 GBG87745.1 - 0.038 13.7 8.7 0.092 12.5 0.7 2.2 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Voldacs PF03517.13 GBG87745.1 - 9.4 6.4 10.9 1.2 9.3 2.2 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling SEN1_N PF12726.7 GBG87746.1 - 1.5e-14 53.2 0.1 2e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal Myb_DNA-bind_5 PF13873.6 GBG87746.1 - 0.16 12.1 0.8 27 4.9 0.0 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG87747.1 - 2.9e-06 27.0 0.0 5.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG87747.1 - 0.0032 17.7 0.6 0.022 15.0 0.3 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG87747.1 - 0.0098 15.7 1.3 0.016 15.0 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Strep_SA_rep PF06696.11 GBG87747.1 - 0.16 12.0 3.0 0.14 12.2 0.4 2.2 2 0 0 2 2 2 0 Streptococcal surface antigen repeat zf-CCHC PF00098.23 GBG87747.1 - 5.9 7.2 5.3 0.72 10.0 1.0 1.8 2 0 0 2 2 2 0 Zinc knuckle End3 PF12761.7 GBG87748.1 - 0.12 12.5 0.4 0.6 10.2 0.1 2.0 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF5069 PF16798.5 GBG87748.1 - 0.13 12.5 0.6 3.6 7.8 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5069) Asp_protease_2 PF13650.6 GBG87749.1 - 1.5e-07 31.9 0.0 3.2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87749.1 - 3.3e-07 30.8 0.1 6.9e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87749.1 - 0.0064 16.3 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG87749.1 - 0.018 15.1 2.9 0.032 14.3 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.20 GBG87749.1 - 0.15 12.4 0.0 0.43 10.9 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease AAA_11 PF13086.6 GBG87750.1 - 3.3e-19 69.7 3.9 1.2e-18 67.9 2.7 2.1 1 1 0 1 1 1 1 AAA domain Asp_protease_2 PF13650.6 GBG87750.1 - 6.7e-07 29.9 0.0 2.7e-06 27.9 0.0 2.1 2 0 0 2 2 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87750.1 - 2.3e-06 27.4 0.0 6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG87750.1 - 8.7e-06 26.2 0.0 2.9e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG87750.1 - 0.0055 16.9 0.2 2.8 8.3 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein AAA_30 PF13604.6 GBG87750.1 - 0.0078 15.9 0.4 0.0078 15.9 0.4 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GBG87750.1 - 0.0078 16.5 0.0 0.0078 16.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain Asp_protease PF09668.10 GBG87750.1 - 0.0098 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease KaiB PF07689.12 GBG87750.1 - 0.13 12.0 0.0 0.43 10.4 0.0 1.9 1 0 0 1 1 1 0 KaiB domain AAA_16 PF13191.6 GBG87750.1 - 0.15 12.4 1.4 0.47 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 GBG87750.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_12 PF13087.6 GBG87751.1 - 1.1e-60 204.7 0.0 1.7e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG87751.1 - 1.4e-27 97.2 2.2 1.4e-27 97.2 2.2 3.1 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GBG87751.1 - 0.0007 19.4 0.1 0.0022 17.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG87751.1 - 0.096 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 GBG87751.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SRRM_C PF15230.6 GBG87752.1 - 0.045 14.3 4.7 0.21 12.2 4.7 2.1 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus PLATZ PF04640.14 GBG87753.1 - 6.4e-18 65.2 0.0 1.4e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 PLATZ transcription factor FGF PF00167.18 GBG87753.1 - 0.022 14.9 0.1 1e+02 3.0 0.0 4.2 1 1 4 5 5 5 0 Fibroblast growth factor zf-B_box PF00643.24 GBG87753.1 - 0.049 13.8 4.5 2.7 8.2 0.3 2.7 2 0 0 2 2 2 0 B-box zinc finger RT_RNaseH PF17917.1 GBG87754.1 - 3.6e-29 101.1 0.0 7.3e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87754.1 - 8.2e-29 99.6 0.0 1.9e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87754.1 - 2.3e-28 99.2 0.1 3.6e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87754.1 - 4e-09 36.5 0.1 8.7e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87754.1 - 8.2e-06 26.0 0.0 3.4e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG87754.1 - 0.074 13.3 0.2 0.19 12.0 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG87755.1 - 2e-07 30.8 4.6 4.2e-07 29.7 4.6 1.6 1 0 0 1 1 1 1 Zinc knuckle CheY-binding PF09078.11 GBG87755.1 - 0.018 15.1 1.5 0.064 13.4 0.3 2.4 2 0 0 2 2 2 0 CheY binding FAM176 PF14851.6 GBG87755.1 - 0.43 10.2 11.6 0.11 12.1 6.6 2.2 2 0 0 2 2 2 0 FAM176 family EIIBC-GUT_N PF03612.14 GBG87755.1 - 0.79 9.4 8.5 0.068 12.9 1.6 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_C37 PF05416.12 GBG87756.1 - 0.38 9.2 6.4 0.48 8.9 6.4 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF3381 PF11861.8 GBG87756.1 - 0.87 9.4 15.0 1.4 8.7 15.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Presenilin PF01080.17 GBG87756.1 - 1.4 7.6 7.7 1.7 7.3 7.7 1.2 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 GBG87756.1 - 2.4 7.5 21.7 3.3 7.1 21.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG87756.1 - 4.7 5.3 18.8 5.9 5.0 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 GBG87756.1 - 5.9 6.2 22.6 9.4 5.5 22.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RVT_1 PF00078.27 GBG87757.1 - 1.2e-22 80.5 0.1 2.6e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87757.1 - 3e-19 68.9 0.1 6.4e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87757.1 - 3.1e-14 53.2 0.0 8.8e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG87757.1 - 4.2e-13 49.5 0.5 1.1e-12 48.2 0.5 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG87757.1 - 1.8e-05 25.2 0.1 5.8e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87757.1 - 7.3e-05 22.6 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG87757.1 - 0.00021 21.3 0.1 0.00054 19.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG87757.1 - 0.0011 19.5 0.1 0.0043 17.7 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 GBG87757.1 - 0.01 15.6 0.1 0.042 13.6 0.0 1.9 2 0 0 2 2 2 0 Putative peptidase (DUF1758) zf-H2C2 PF09337.10 GBG87757.1 - 0.16 12.2 0.0 0.5 10.6 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG87758.1 - 8.7e-22 77.4 0.0 8.2e-21 74.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87758.1 - 2e-21 75.9 0.0 6.8e-21 74.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87758.1 - 9.8e-09 35.1 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG87758.1 - 3.9e-05 24.1 0.0 9.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87758.1 - 0.00015 22.4 0.0 0.00043 20.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87758.1 - 0.087 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Response_reg PF00072.24 GBG87760.1 - 2.8e-22 79.0 3.6 3.8e-22 78.6 0.2 2.7 3 0 0 3 3 3 1 Response regulator receiver domain HATPase_c PF02518.26 GBG87760.1 - 8e-22 77.9 0.4 1.1e-13 51.7 0.0 3.2 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GBG87760.1 - 5.4e-06 26.4 0.7 0.014 15.4 0.0 3.4 3 0 0 3 3 3 2 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GBG87760.1 - 0.033 14.0 0.0 0.096 12.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase T6PP_N PF18572.1 GBG87760.1 - 0.1 12.5 2.2 0.14 12.0 0.2 2.1 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain RT_RNaseH_2 PF17919.1 GBG87761.1 - 1.3e-33 115.0 0.0 2.2e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87761.1 - 2.1e-30 105.9 0.1 3.8e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87761.1 - 1.8e-29 102.1 0.1 3.2e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87761.1 - 4.3e-19 68.4 0.1 9e-19 67.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG87761.1 - 0.02 15.1 0.0 0.1 12.8 0.0 2.3 1 0 0 1 1 1 0 H2C2 zinc finger DUF2584 PF10763.9 GBG87761.1 - 0.056 13.6 0.1 8.5 6.6 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2584) VAPB_antitox PF02697.14 GBG87761.1 - 5.4 7.9 6.6 3 8.7 2.1 2.9 3 1 1 4 4 4 0 Putative antitoxin CHASE PF03924.13 GBG87762.1 - 2.9e-14 53.4 0.0 4.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 CHASE domain HisKA PF00512.25 GBG87762.1 - 0.00025 21.0 0.0 0.00075 19.5 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 GBG87765.1 - 3.6e-09 37.1 0.0 7.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RVT_1 PF00078.27 GBG87765.1 - 0.0002 20.9 0.0 0.00087 18.9 0.0 2.0 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) T6PP_N PF18572.1 GBG87765.1 - 0.0094 15.8 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain RT_RNaseH_2 PF17919.1 GBG87766.1 - 2.9e-25 88.2 0.0 7.7e-25 86.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87766.1 - 3.8e-22 78.6 0.2 1.6e-21 76.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87766.1 - 3e-19 68.9 0.3 8.1e-19 67.5 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG87766.1 - 1.4e-06 28.8 0.0 4.2e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87766.1 - 2.1e-06 28.2 0.0 7.5e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87766.1 - 4.1e-06 26.6 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG87766.1 - 0.00032 20.6 0.3 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG87766.1 - 0.0006 20.0 0.1 0.0015 18.7 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG87766.1 - 0.0014 18.8 0.0 0.0039 17.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG87766.1 - 0.008 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Response_reg PF00072.24 GBG87766.1 - 0.024 14.8 0.0 0.072 13.3 0.0 1.9 1 0 0 1 1 1 0 Response regulator receiver domain DUF659 PF04937.15 GBG87768.1 - 1.6e-18 67.0 0.0 2.3e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Na_trans_assoc PF06512.13 GBG87769.1 - 0.01 16.1 13.8 0.021 15.1 13.8 1.6 1 1 0 1 1 1 0 Sodium ion transport-associated TFIIF_alpha PF05793.12 GBG87769.1 - 0.22 10.1 26.9 0.31 9.6 26.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GBG87769.1 - 0.34 9.2 21.3 0.44 8.8 21.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG87769.1 - 0.47 9.8 30.7 0.62 9.4 30.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG87769.1 - 1.1 7.4 30.9 1.6 6.8 30.9 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG87769.1 - 2 7.7 30.5 2.9 7.1 30.5 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GBG87769.1 - 2.4 6.8 9.1 3 6.5 9.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 GBG87769.1 - 5.4 6.5 20.7 7.6 6.0 20.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3008 PF11450.8 GBG87770.1 - 1.1 9.5 9.1 0.067 13.4 3.9 1.7 1 1 1 2 2 2 0 Protein of unknwon function (DUF3008) TFIIA PF03153.13 GBG87771.1 - 0.042 13.9 6.3 0.046 13.7 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2563 PF10817.8 GBG87771.1 - 0.8 10.3 5.5 1.1 9.9 2.8 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2563) DUF4407 PF14362.6 GBG87771.1 - 1.5 8.1 17.5 2.3 7.5 17.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 GBG87771.1 - 3.3 8.1 9.6 0.44 11.0 2.6 2.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Abhydrolase_6 PF12697.7 GBG87772.1 - 9.6e-17 62.3 0.4 9.6e-17 62.3 0.4 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG87772.1 - 9.5e-12 44.7 0.3 1.4e-11 44.2 0.3 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GBG87772.1 - 2.3e-11 43.8 0.1 3.6e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 GBG87772.1 - 9.1e-08 32.5 0.0 1.4e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 GBG87772.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 GBG87772.1 - 0.0047 15.9 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 GBG87772.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 GBG87772.1 - 0.018 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 GBG87772.1 - 0.023 14.5 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 GBG87772.1 - 0.027 14.1 0.1 0.065 12.9 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.13 GBG87772.1 - 0.035 14.0 0.1 0.068 13.0 0.1 1.5 1 0 0 1 1 1 0 Serine hydrolase LIDHydrolase PF10230.9 GBG87772.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Aminotran_5 PF00266.19 GBG87775.1 - 1.8e-141 471.4 0.0 2.2e-141 471.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GBG87775.1 - 2e-06 26.6 0.0 0.00043 18.9 0.0 2.5 3 0 0 3 3 3 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GBG87775.1 - 1.4e-05 24.6 0.2 2.4e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family IMUP PF15761.5 GBG87775.1 - 7.5 7.3 17.3 14 6.5 2.8 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein Integrase_H2C2 PF17921.1 GBG87776.1 - 3.3e-14 52.7 0.1 9.2e-14 51.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87776.1 - 9.2e-13 48.4 0.0 2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG87776.1 - 1.3e-07 31.3 0.0 2.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG87776.1 - 3.1e-07 30.9 0.0 6.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87776.1 - 0.00057 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87776.1 - 0.004 16.9 0.3 0.0077 16.0 0.3 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG87776.1 - 0.067 13.5 0.0 0.28 11.5 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG87776.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger zf-BED PF02892.15 GBG87776.1 - 0.072 13.1 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 BED zinc finger DUF3797 PF12677.7 GBG87777.1 - 0.0077 16.1 1.5 28 4.7 0.1 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF3797) Na_trans_assoc PF06512.13 GBG87778.1 - 0.00092 19.5 3.1 0.00092 19.5 3.1 2.1 1 1 0 1 1 1 1 Sodium ion transport-associated SAPS PF04499.15 GBG87778.1 - 0.025 13.4 0.8 0.039 12.8 0.3 1.3 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 GBG87778.1 - 1.6 8.0 26.0 3.3 6.9 26.0 1.5 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GBG87778.1 - 4.8 6.8 21.6 9.3 5.9 21.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PLAC8 PF04749.17 GBG87779.1 - 3.8e-23 82.3 7.4 4.9e-23 82.0 7.4 1.1 1 0 0 1 1 1 1 PLAC8 family RT_RNaseH_2 PF17919.1 GBG87780.1 - 1.3e-34 118.2 0.0 2.4e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87780.1 - 1e-29 102.9 0.0 2.1e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87780.1 - 5.5e-23 81.7 0.0 1e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87780.1 - 3.1e-18 65.6 0.6 6.6e-18 64.6 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87780.1 - 2.7e-13 50.1 0.0 5.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG87781.1 - 1.1e-34 118.4 0.0 2.1e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87781.1 - 8.9e-30 103.1 0.0 1.8e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87781.1 - 2.7e-18 65.8 0.6 5.9e-18 64.7 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87781.1 - 2.4e-13 50.3 0.0 5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG87781.1 - 1.1e-09 38.1 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_11 PF13086.6 GBG87785.1 - 6.4e-18 65.5 1.9 1.5e-11 44.6 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_12 PF13087.6 GBG87785.1 - 1.6e-17 63.8 0.0 2.7e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG87785.1 - 3.2e-06 27.0 0.5 0.015 15.1 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GBG87785.1 - 0.0021 18.4 0.2 0.94 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 GBG87785.1 - 0.11 11.5 0.0 0.87 8.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2470 PF10615.9 GBG87787.1 - 3.6e-15 56.3 0.2 7.3e-15 55.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyrid_oxidase_2 PF13883.6 GBG87787.1 - 5.6e-10 39.4 0.0 1.7e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 GBG87787.1 - 1e-05 25.6 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase bHLH-MYC_N PF14215.6 GBG87789.1 - 1.4e-27 97.1 1.8 1.4e-27 97.1 1.8 3.1 3 1 0 3 3 3 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal LcrG PF07216.12 GBG87789.1 - 0.34 10.9 2.6 1.4 8.9 2.6 2.0 1 0 0 1 1 1 0 LcrG protein CMS1 PF14617.6 GBG87790.1 - 0.2 11.0 7.6 0.3 10.4 7.6 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit RPA43_OB PF17875.1 GBG87790.1 - 0.3 11.7 6.5 0.47 11.1 6.5 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF5401 PF17380.2 GBG87790.1 - 0.54 8.3 13.5 0.69 7.9 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Vfa1 PF08432.10 GBG87790.1 - 1.1 9.5 11.7 1.6 9.0 11.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.10 GBG87790.1 - 5.7 7.0 9.3 19 5.3 9.3 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3138 PF11336.8 GBG87791.1 - 0.53 8.8 1.3 0.74 8.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RVT_1 PF00078.27 GBG87794.1 - 5.7e-24 84.9 0.2 5.7e-24 84.9 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87794.1 - 1.2e-15 57.3 0.0 2.6e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87794.1 - 9.3e-15 54.5 0.2 6.9e-14 51.7 0.1 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG87794.1 - 1.5e-14 54.2 0.0 3.3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG87794.1 - 0.00024 21.4 0.0 0.00052 20.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG87794.1 - 0.077 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Ntox1 PF15500.6 GBG87795.1 - 0.3 11.5 8.0 4 7.8 4.1 2.4 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 PIEZO PF15917.5 GBG87795.1 - 0.58 9.6 10.4 0.54 9.7 9.3 1.5 1 1 0 1 1 1 0 Piezo DUF3006 PF11213.8 GBG87795.1 - 1.7 8.9 6.1 1.1 9.5 2.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) RT_RNaseH_2 PF17919.1 GBG87796.1 - 3.6e-26 91.1 0.0 6.6e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87796.1 - 2.6e-22 79.1 0.0 5.9e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG87796.1 - 0.00011 22.1 1.6 0.00024 21.0 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG87796.1 - 0.058 13.2 0.5 0.12 12.2 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG87796.1 - 0.15 11.5 0.3 5.7 6.4 0.1 2.7 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) BRD4_CDT PF17105.5 GBG87797.1 - 0.0034 17.0 0.1 0.01 15.4 0.1 1.8 1 0 0 1 1 1 1 C-terminal domain of bromodomain protein 4 zf-CCHC PF00098.23 GBG87798.1 - 0.0029 17.6 2.2 0.0047 17.0 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle DivIC PF04977.15 GBG87798.1 - 0.048 13.4 0.2 0.048 13.4 0.2 5.1 4 2 1 5 5 5 0 Septum formation initiator zf-CCHC_2 PF13696.6 GBG87798.1 - 0.051 13.4 2.5 0.081 12.8 2.5 1.3 1 0 0 1 1 1 0 Zinc knuckle TolA_bind_tri PF16331.5 GBG87798.1 - 0.057 13.5 6.8 0.082 13.0 0.2 3.5 3 1 1 4 4 4 0 TolA binding protein trimerisation APC_N_CC PF16689.5 GBG87798.1 - 3.2 7.9 8.0 1.4 9.0 1.4 3.4 3 1 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1943 PF09172.11 GBG87802.1 - 0.19 10.9 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DDE_Tnp_4 PF13359.6 GBG87804.1 - 3.2e-28 98.4 0.0 8.1e-28 97.1 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87804.1 - 1.5e-14 54.1 0.0 2.4e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG87804.1 - 0.036 13.7 0.0 5 6.7 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain GATA PF00320.27 GBG87806.1 - 2e-17 62.5 3.5 5e-17 61.2 3.5 1.8 1 0 0 1 1 1 1 GATA zinc finger YL1 PF05764.13 GBG87806.1 - 0.0006 20.0 2.8 0.0006 20.0 2.8 3.1 3 0 0 3 3 3 1 YL1 nuclear protein TFIIA PF03153.13 GBG87806.1 - 0.0078 16.3 4.8 0.025 14.6 4.8 1.8 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit eIF-3c_N PF05470.12 GBG87806.1 - 1.5 7.0 8.1 0.075 11.3 0.5 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FAM176 PF14851.6 GBG87808.1 - 0.031 14.0 7.4 0.033 13.8 7.4 1.1 1 0 0 1 1 1 0 FAM176 family DUF2052 PF09747.9 GBG87808.1 - 0.13 12.4 11.9 0.14 12.2 11.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Eapp_C PF10238.9 GBG87808.1 - 0.29 11.2 6.0 0.31 11.1 6.0 1.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein RPN2_C PF18004.1 GBG87808.1 - 0.34 10.8 9.7 0.36 10.7 9.7 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain G0-G1_switch_2 PF15103.6 GBG87808.1 - 0.43 11.0 5.0 0.51 10.8 5.0 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF4820 PF16091.5 GBG87808.1 - 0.55 9.6 6.1 0.59 9.5 6.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CDC45 PF02724.14 GBG87808.1 - 0.71 8.1 9.5 0.77 8.0 9.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG87808.1 - 0.86 9.4 9.8 0.93 9.3 9.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Afi1 PF07792.12 GBG87808.1 - 1.2 9.6 7.0 1.2 9.6 7.0 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Paf1 PF03985.13 GBG87808.1 - 1.6 7.6 14.9 1.7 7.5 14.9 1.0 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.14 GBG87808.1 - 1.6 8.4 11.7 1.8 8.3 11.7 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleo_P87 PF07267.11 GBG87808.1 - 1.9 7.3 5.8 2 7.1 5.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 GBG87808.1 - 1.9 7.2 5.0 1.9 7.1 5.0 1.0 1 0 0 1 1 1 0 Presenilin Myc_N PF01056.18 GBG87808.1 - 2.8 7.8 11.3 2.7 7.8 11.3 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 GBG87808.1 - 2.9 6.0 15.4 3.1 5.9 15.4 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG87808.1 - 3.8 6.8 10.8 4.2 6.6 10.8 1.0 1 0 0 1 1 1 0 NOA36 protein Connexin PF00029.19 GBG87808.1 - 4.2 7.1 6.1 4.5 7.0 6.1 1.0 1 0 0 1 1 1 0 Connexin HSP90 PF00183.18 GBG87808.1 - 4.5 6.0 12.2 5 5.9 12.2 1.0 1 0 0 1 1 1 0 Hsp90 protein TRAP_alpha PF03896.16 GBG87808.1 - 5.3 6.2 8.9 5.6 6.1 8.9 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4746 PF15928.5 GBG87808.1 - 5.8 6.2 14.2 6.3 6.1 14.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PBP_sp32 PF07222.12 GBG87808.1 - 8.2 5.8 17.1 8.9 5.7 17.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 V_ATPase_I PF01496.19 GBG87808.1 - 8.3 4.2 6.8 8.8 4.1 6.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family dsDNA_bind PF01984.20 GBG87809.1 - 4.4e-30 104.2 2.3 4.8e-30 104.1 2.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Synaphin PF05835.12 GBG87809.1 - 0.84 9.9 8.3 1.5 9.1 8.3 1.6 1 1 0 1 1 1 0 Synaphin protein Hyccin PF09790.9 GBG87810.1 - 0.003 16.7 0.2 0.0057 15.8 0.2 1.3 1 0 0 1 1 1 1 Hyccin Plug PF07715.15 GBG87810.1 - 8.1 7.1 9.3 15 6.2 9.3 1.5 1 1 0 1 1 1 0 TonB-dependent Receptor Plug Domain RNA_pol_I_A49 PF06870.12 GBG87811.1 - 2.2e-60 204.5 0.2 2.6e-35 122.0 0.6 2.1 2 0 0 2 2 2 2 A49-like RNA polymerase I associated factor DUF4766 PF15973.5 GBG87811.1 - 0.58 10.8 24.7 2 9.0 3.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) Fip1 PF05182.13 GBG87812.1 - 4.8e-23 80.4 0.8 8.7e-23 79.6 0.8 1.4 1 0 0 1 1 1 1 Fip1 motif NUDIX PF00293.28 GBG87816.1 - 1.5e-09 37.9 3.6 8.2e-09 35.6 3.6 2.0 1 1 0 1 1 1 1 NUDIX domain PPP4R2 PF09184.11 GBG87817.1 - 1.7 8.1 11.9 8 6.0 6.0 2.2 2 0 0 2 2 2 0 PPP4R2 RT_RNaseH PF17917.1 GBG87818.1 - 2.9e-19 69.3 0.0 5.9e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87818.1 - 4.3e-18 65.2 0.0 8.8e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87818.1 - 3.7e-12 46.5 0.0 1e-11 45.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG87818.1 - 2.5e-09 37.1 2.8 1e-08 35.1 2.8 2.1 1 1 0 1 1 1 1 Integrase zinc binding domain Topo_Zn_Ribbon PF08272.11 GBG87820.1 - 0.094 12.4 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RT_RNaseH PF17917.1 GBG87821.1 - 7.4e-22 77.6 0.0 1.9e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87821.1 - 9.5e-22 76.9 0.0 2.3e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87821.1 - 9e-14 51.7 0.0 1.7e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG87821.1 - 3.4e-08 33.5 3.4 9.7e-08 32.0 3.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG87821.1 - 4.6e-08 33.5 0.0 1.2e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG87821.1 - 9.7e-08 31.8 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG87821.1 - 1.9e-05 25.2 0.0 4.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87821.1 - 0.014 15.2 1.2 0.033 14.0 1.2 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG87821.1 - 0.024 15.0 0.0 0.094 13.0 0.0 2.1 1 0 0 1 1 1 0 Retroviral aspartyl protease EF-1_beta_acid PF10587.9 GBG87821.1 - 7.6 7.1 8.8 27 5.3 8.8 2.0 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region RVP_2 PF08284.11 GBG87822.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG87822.1 - 0.088 12.9 1.9 0.18 12.0 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG87823.1 - 1.6e-28 99.8 0.0 3.4e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG87823.1 - 4.1e-08 33.7 0.0 2.1e-07 31.4 0.0 2.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87823.1 - 1.6e-07 31.8 0.0 5.6e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87823.1 - 2.7e-05 24.0 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG87823.1 - 2.8e-05 23.9 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG87823.1 - 0.00027 21.1 0.2 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Cnn_1N PF07989.11 GBG87823.1 - 4.5 7.5 19.1 0.37 11.0 10.8 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 RVT_1 PF00078.27 GBG87824.1 - 2e-29 102.7 0.0 4.4e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87824.1 - 4e-19 68.5 0.0 1.8e-18 66.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87824.1 - 3e-16 59.3 0.0 6.5e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG87824.1 - 2.9e-10 40.4 0.0 8e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG87824.1 - 7.4e-08 32.2 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG87824.1 - 2.3e-07 31.0 0.0 1.5e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG87824.1 - 6.8e-07 29.8 0.0 3e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87824.1 - 4.3e-05 24.0 0.0 0.00013 22.4 0.0 1.9 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87824.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Nif11 PF07862.11 GBG87824.1 - 0.03 14.6 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 1 0 Nif11 domain WTX PF09422.10 GBG87824.1 - 0.096 11.7 1.1 0.21 10.6 1.1 1.5 1 0 0 1 1 1 0 WTX protein RVT_1 PF00078.27 GBG87825.1 - 8.3e-34 117.0 0.0 1.3e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87827.1 - 6.5e-23 80.7 0.1 3.5e-22 78.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87827.1 - 3.5e-22 78.7 0.0 7e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87827.1 - 5.5e-18 65.3 0.0 1.5e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87827.1 - 6.4e-17 61.4 0.1 1.3e-16 60.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87827.1 - 1e-09 38.6 0.0 3e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG87827.1 - 1.6e-06 28.0 0.0 3.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87827.1 - 0.00011 22.8 0.0 0.00031 21.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87827.1 - 0.0061 17.1 0.0 0.022 15.3 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG87827.1 - 0.0075 16.5 0.0 0.025 14.8 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Abhydrolase_1 PF00561.20 GBG87828.1 - 2.2e-16 60.3 0.0 3e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GBG87828.1 - 1.9e-13 51.6 0.0 2.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG87828.1 - 8.8e-08 31.7 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cupin_1 PF00190.22 GBG87828.1 - 0.0088 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Cupin Ser_hydrolase PF06821.13 GBG87828.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase BAAT_C PF08840.11 GBG87828.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal RVT_1 PF00078.27 GBG87829.1 - 1.4e-19 70.5 0.0 2.4e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG87829.1 - 1.1e-10 41.3 0.0 2.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 GBG87829.1 - 2.1e-05 24.3 3.5 5.2e-05 23.1 3.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG87829.1 - 0.23 11.2 1.0 0.63 9.8 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle PEHE PF15275.6 GBG87829.1 - 5.8 7.5 11.7 4.9 7.8 7.9 2.6 2 0 0 2 2 2 0 PEHE domain Nop14 PF04147.12 GBG87830.1 - 0.0078 14.5 8.3 0.01 14.1 8.3 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG87830.1 - 0.011 15.1 10.2 0.019 14.4 10.2 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG87830.1 - 0.024 13.0 10.4 0.033 12.5 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 GBG87830.1 - 0.23 11.8 14.7 0.41 10.9 14.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SbmA_BacA PF05992.12 GBG87832.1 - 0.05 13.0 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 SbmA/BacA-like family RT_RNaseH_2 PF17919.1 GBG87834.1 - 5.2e-31 106.6 0.0 1.9e-30 104.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87834.1 - 4.7e-30 104.0 0.0 1.5e-29 102.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87834.1 - 1.1e-15 57.8 0.0 2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG87834.1 - 6e-14 51.9 0.4 1.3e-13 50.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG87834.1 - 3.2e-06 27.0 0.0 6.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87834.1 - 5.3e-06 27.0 0.0 1.6e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87834.1 - 0.001 19.6 0.0 0.0045 17.5 0.0 2.2 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG87834.1 - 0.0012 19.0 0.2 0.0034 17.6 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG87834.1 - 0.083 13.2 1.8 0.59 10.4 0.0 3.3 4 0 0 4 4 3 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG87834.1 - 0.16 11.8 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease Es2 PF09751.9 GBG87834.1 - 0.25 11.0 10.1 0.46 10.2 10.1 1.3 1 0 0 1 1 1 0 Nuclear protein Es2 Phage_HK97_TLTM PF06120.11 GBG87834.1 - 0.83 8.8 17.0 1.6 7.8 17.0 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Peptidase_M14 PF00246.24 GBG87835.1 - 2e-13 50.8 0.0 6.1e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 GBG87835.1 - 0.048 12.7 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Beta-prism_lec PF16458.5 GBG87836.1 - 0.26 11.3 2.7 3.5 7.6 2.0 2.8 1 1 0 1 1 1 0 Beta-prism lectin BBS1 PF14779.6 GBG87837.1 - 1.1e-82 277.3 0.1 6e-50 170.1 0.0 2.3 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 GBG87837.1 - 0.002 18.2 0.0 0.4 10.7 0.0 3.8 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 GBG87837.1 - 0.018 14.4 0.1 0.25 10.7 0.0 2.4 2 1 0 3 3 3 0 PTHB1 N-terminus ARL2_Bind_BART PF11527.8 GBG87838.1 - 0.00096 19.2 0.1 0.00096 19.2 0.1 2.5 3 0 0 3 3 3 1 The ARF-like 2 binding protein BART CpXC PF14353.6 GBG87838.1 - 0.053 13.6 0.8 0.2 11.7 0.8 2.0 1 0 0 1 1 1 0 CpXC protein Vps26 PF03643.15 GBG87839.1 - 8.7e-125 415.2 2.3 9.9e-125 415.1 2.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GBG87839.1 - 0.003 17.6 0.3 1.2 9.2 0.1 3.1 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GBG87839.1 - 0.0096 16.4 0.1 5 7.6 0.0 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain RVT_1 PF00078.27 GBG87840.1 - 3.6e-09 36.5 0.0 5.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG87841.1 - 7.7e-06 26.2 2.7 1.6e-05 25.2 2.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG87841.1 - 0.084 13.2 2.0 0.22 11.9 2.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG87841.1 - 0.11 12.6 4.4 0.21 11.7 4.4 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain GRP PF07172.11 GBG87841.1 - 1.7 9.4 0.0 1.7 9.4 0.0 2.9 3 1 0 3 3 3 0 Glycine rich protein family DDE_Tnp_4 PF13359.6 GBG87842.1 - 1.1e-27 96.6 0.0 1.8e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87842.1 - 8.3e-14 51.7 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG87842.1 - 0.00016 21.4 0.2 0.011 15.4 0.0 3.1 4 1 0 4 4 4 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG87842.1 - 0.068 13.6 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain YojJ PF10372.9 GBG87843.1 - 3.8 7.7 13.0 0.83 9.8 8.5 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus zf-CCHC PF00098.23 GBG87844.1 - 5.3e-07 29.4 4.0 9.6e-07 28.6 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF2048 PF09752.9 GBG87844.1 - 0.028 13.5 0.8 0.036 13.2 0.8 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 NYD-SP28 PF14772.6 GBG87844.1 - 0.029 14.4 11.9 0.029 14.4 11.9 2.2 2 0 0 2 2 2 0 Sperm tail PMI_typeI PF01238.21 GBG87844.1 - 0.056 12.6 2.0 0.078 12.2 2.0 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I IBB PF01749.20 GBG87844.1 - 1.6 9.2 15.6 0.41 11.1 9.9 2.2 2 0 0 2 2 2 0 Importin beta binding domain COR PF16095.5 GBG87845.1 - 1.5e-08 34.7 0.0 5.5e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 GBG87845.1 - 1.5e-06 28.4 0.0 3.6e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RVT_1 PF00078.27 GBG87846.1 - 5.1e-29 101.4 0.0 8.4e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87846.1 - 3.4e-20 71.9 0.0 9.6e-16 57.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87846.1 - 3.9e-16 58.9 0.0 7.4e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87846.1 - 8.1e-10 38.9 0.0 2.4e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG87846.1 - 2.9e-08 33.9 0.0 6.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG87846.1 - 2.3e-05 24.5 0.0 5.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger SAPS PF04499.15 GBG87847.1 - 0.096 11.5 3.4 0.11 11.3 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 GBG87847.1 - 0.12 11.8 17.0 0.14 11.5 17.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG87847.1 - 0.22 9.7 17.7 0.26 9.4 17.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG87847.1 - 0.26 9.5 13.4 0.32 9.2 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG87847.1 - 0.65 9.3 16.3 0.81 9.0 16.3 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG87847.1 - 5.1 5.7 7.6 6.6 5.4 7.6 1.1 1 0 0 1 1 1 0 Presenilin Smg4_UPF3 PF03467.15 GBG87847.1 - 7.4 6.6 9.9 11 6.0 9.9 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family CobT PF06213.12 GBG87847.1 - 8.9 5.6 22.1 13 5.1 22.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peptidase_C48 PF02902.19 GBG87848.1 - 2.9e-08 33.8 0.3 5e-08 33.0 0.3 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TMEM190 PF15431.6 GBG87848.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 190 ATS PF15445.6 GBG87851.1 - 0.29 10.5 0.4 0.34 10.3 0.4 1.1 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 RT_RNaseH_2 PF17919.1 GBG87853.1 - 1.9e-22 79.2 0.2 4.2e-22 78.1 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87853.1 - 1.4e-14 54.2 0.0 3.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG87853.1 - 2.4e-13 50.3 0.0 6.2e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain M16C_assoc PF08367.11 GBG87853.1 - 5.4e-13 48.7 0.0 1.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 GBG87853.1 - 2.6e-12 47.2 0.1 7.5e-09 35.9 0.0 3.8 3 1 0 3 3 3 2 Peptidase M16 inactive domain RT_RNaseH PF17917.1 GBG87853.1 - 4.6e-09 36.5 0.1 1.3e-08 35.0 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87853.1 - 1.2e-07 31.7 0.2 4.3e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG87853.1 - 0.002 18.3 0.1 0.0047 17.1 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG87853.1 - 0.021 14.6 0.0 0.071 12.9 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain DUF2067 PF09840.9 GBG87853.1 - 0.022 14.3 0.0 0.067 12.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) ABC2_membrane_3 PF12698.7 GBG87855.1 - 0.029 13.5 3.4 0.035 13.2 3.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RVT_1 PF00078.27 GBG87857.1 - 2e-34 119.1 0.1 7e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG87857.1 - 2.9e-11 42.9 14.0 2.5e-05 24.2 3.2 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 GBG87857.1 - 0.00013 21.7 16.1 0.048 13.5 4.1 2.6 2 0 0 2 2 2 2 Zinc knuckle Retrotrans_gag PF03732.17 GBG87857.1 - 0.038 14.3 0.1 23 5.3 0.0 3.4 2 0 0 2 2 2 0 Retrotransposon gag protein DUF1726 PF08351.11 GBG87857.1 - 0.34 10.9 1.2 45 4.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1726) Na_trans_assoc PF06512.13 GBG87857.1 - 5 7.4 23.1 11 6.3 23.1 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated Mito_fiss_reg PF05308.11 GBG87857.1 - 6.2 6.8 17.0 1.8 8.6 1.4 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator MRP-S35 PF10246.9 GBG87858.1 - 0.095 12.7 0.1 16 5.5 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 ASXH PF13919.6 GBG87858.1 - 0.85 9.6 5.5 7.8 6.5 0.3 3.5 3 1 0 3 3 3 0 Asx homology domain RT_RNaseH_2 PF17919.1 GBG87860.1 - 4.5e-18 65.1 0.0 9.7e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87860.1 - 3.3e-17 62.7 0.0 6.8e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87860.1 - 8.8e-09 35.4 0.1 2.4e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain CDC45 PF02724.14 GBG87860.1 - 5.6 5.1 53.9 0.019 13.3 28.8 2.5 3 0 0 3 3 3 0 CDC45-like protein Integrase_H2C2 PF17921.1 GBG87861.1 - 1.2e-17 63.8 0.2 3.1e-17 62.4 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87861.1 - 2.5e-14 53.5 0.0 5.4e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG87861.1 - 0.0043 17.3 0.2 0.033 14.5 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG87861.1 - 0.0084 16.6 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87861.1 - 0.011 16.3 0.0 0.027 15.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG87861.1 - 0.023 14.9 0.0 0.1 12.9 0.0 2.2 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC_2 PF13696.6 GBG87861.1 - 0.093 12.6 0.8 0.19 11.6 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG87862.1 - 9e-61 205.2 0.5 6.4e-30 104.3 0.1 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87862.1 - 1.9e-57 191.5 0.0 1.9e-29 101.6 0.0 3.3 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87862.1 - 5.3e-41 139.2 0.0 4.2e-21 75.2 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87862.1 - 1e-14 54.4 2.0 1.5e-14 53.8 0.1 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG87862.1 - 4e-08 33.1 0.0 0.0033 17.2 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG87862.1 - 1.3e-06 28.9 0.0 7.4e-05 23.3 0.0 3.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87862.1 - 0.00012 22.6 0.0 0.0024 18.4 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87862.1 - 0.0096 15.7 0.0 0.087 12.6 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.10 GBG87862.1 - 0.45 10.8 1.7 0.69 10.2 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger SURF2 PF05477.11 GBG87864.1 - 0.42 10.3 10.3 0.61 9.7 10.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4746 PF15928.5 GBG87864.1 - 3 7.2 12.1 4 6.8 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EGF PF00008.27 GBG87865.1 - 1.5e-06 28.4 33.6 0.041 14.2 5.1 3.4 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 GBG87865.1 - 0.00067 20.2 32.8 0.13 12.9 5.1 3.9 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_2 PF07974.13 GBG87865.1 - 1.6 9.1 44.9 1.3 9.5 11.9 3.4 3 0 0 3 3 3 0 EGF-like domain RT_RNaseH_2 PF17919.1 GBG87866.1 - 5.1e-31 106.7 0.0 1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87866.1 - 8.6e-28 97.4 0.0 1.4e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87866.1 - 2.7e-26 91.9 0.0 5.4e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87866.1 - 2.1e-17 62.9 0.2 4.3e-17 62.0 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87866.1 - 4.1e-12 46.3 0.1 3.4e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG87867.1 - 6.7e-24 83.8 0.0 1.5e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87867.1 - 2.4e-22 79.2 0.0 2.2e-21 76.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87867.1 - 0.19 11.2 0.0 0.7 9.4 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1590 PF07629.11 GBG87868.1 - 0.3 10.9 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) DUF365 PF04033.12 GBG87869.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF365) RVT_1 PF00078.27 GBG87870.1 - 1.7e-27 96.4 0.1 2.9e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87870.1 - 1.1e-17 64.2 0.5 2.4e-17 63.1 0.5 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87870.1 - 3.9e-16 58.9 0.2 8.9e-16 57.8 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG87870.1 - 1.7e-11 44.0 0.1 3.8e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87871.1 - 2.4e-29 102.4 0.1 4.3e-29 101.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG87871.1 - 4.3e-16 59.3 0.0 4.1e-07 30.5 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG87871.1 - 6.4e-14 52.3 0.0 1.1e-05 25.9 0.0 3.2 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG87871.1 - 8.4e-12 45.0 0.0 2.8e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease Kelch_4 PF13418.6 GBG87871.1 - 5.5e-10 39.1 1.5 0.0037 17.2 0.0 3.9 3 0 0 3 3 3 3 Galactose oxidase, central domain Asp_protease PF09668.10 GBG87871.1 - 3.5e-09 36.5 0.0 0.004 16.9 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease Retrotrans_gag PF03732.17 GBG87871.1 - 3.7e-05 23.9 2.6 0.32 11.3 0.3 3.5 3 0 0 3 3 3 2 Retrotransposon gag protein Kelch_1 PF01344.25 GBG87871.1 - 0.0029 17.2 0.2 0.35 10.5 0.0 2.8 2 0 0 2 2 2 1 Kelch motif DUF2341 PF10102.9 GBG87871.1 - 0.0089 16.6 0.2 0.034 14.7 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2341) Kelch_5 PF13854.6 GBG87871.1 - 0.029 14.3 0.0 0.2 11.7 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.6 GBG87871.1 - 0.15 12.4 4.7 2.3 8.6 0.0 3.7 4 0 0 4 4 3 0 Kelch motif FtsK_4TM PF13491.6 GBG87872.1 - 0.024 14.3 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE ATG_C PF09333.11 GBG87872.1 - 0.064 13.6 1.9 0.27 11.6 0.0 2.5 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain RT_RNaseH_2 PF17919.1 GBG87873.1 - 2.3e-27 94.9 0.0 1.2e-26 92.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87873.1 - 5.7e-23 81.2 0.0 2e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87873.1 - 5.5e-09 35.9 0.2 0.0018 17.8 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG87873.1 - 6.7e-05 23.4 0.0 0.00024 21.6 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87873.1 - 7.5e-05 23.3 0.0 0.0002 21.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87873.1 - 0.00017 21.4 0.0 0.00038 20.2 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG87873.1 - 0.023 14.9 10.9 0.15 12.3 0.1 4.1 4 0 0 4 4 4 0 Retrotransposon gag protein Prominin PF05478.11 GBG87873.1 - 0.13 10.2 0.8 0.2 9.6 0.8 1.2 1 0 0 1 1 1 0 Prominin Lys-AminoMut_A PF09043.11 GBG87873.1 - 1.9 6.8 6.0 1.7 7.0 0.3 2.1 2 0 0 2 2 2 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Retrotrans_gag PF03732.17 GBG87874.1 - 0.0044 17.3 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG87874.1 - 0.029 14.4 2.9 0.029 14.4 2.9 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation Retrotrans_gag PF03732.17 GBG87876.1 - 2.7e-07 30.8 1.2 0.018 15.3 0.0 3.8 3 0 0 3 3 3 2 Retrotransposon gag protein Chromo PF00385.24 GBG87876.1 - 0.00091 19.1 0.1 0.0026 17.6 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NPV_P10 PF05531.12 GBG87876.1 - 0.19 12.2 6.6 3.8 8.0 0.6 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 GBG87876.1 - 0.55 10.7 0.0 0.55 10.7 0.0 4.1 4 0 0 4 4 4 0 Snapin/Pallidin SlyX PF04102.12 GBG87877.1 - 0.0032 18.0 0.3 0.0032 18.0 0.3 3.4 3 2 0 3 3 3 1 SlyX DUF2730 PF10805.8 GBG87877.1 - 0.091 12.9 0.3 0.47 10.6 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) TRPM_tetra PF16519.5 GBG87877.1 - 0.33 11.1 3.3 4.1 7.6 0.1 2.8 2 1 0 2 2 2 0 Tetramerisation domain of TRPM TolA_bind_tri PF16331.5 GBG87877.1 - 3.7 7.7 12.5 0.3 11.2 4.1 3.2 3 1 1 4 4 4 0 TolA binding protein trimerisation MIF4G_like_2 PF09090.11 GBG87877.1 - 3.9 6.9 11.2 0.46 9.9 0.4 2.0 1 1 1 2 2 2 0 MIF4G like LPP PF04728.13 GBG87879.1 - 0.038 14.4 1.6 14 6.2 0.1 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper ADIP PF11559.8 GBG87879.1 - 0.37 10.9 10.9 0.28 11.3 5.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 GBG87879.1 - 0.38 10.5 12.8 0.27 11.0 0.3 3.4 2 1 1 3 3 3 0 Septum formation initiator YabA PF06156.13 GBG87879.1 - 0.42 11.3 6.9 7.7 7.2 0.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Filament PF00038.21 GBG87879.1 - 0.96 9.0 13.6 3.8 7.0 7.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein FemAB PF02388.16 GBG87880.1 - 0.12 11.3 0.9 0.15 10.9 0.9 1.2 1 0 0 1 1 1 0 FemAB family zf-CCHC PF00098.23 GBG87881.1 - 0.091 12.9 1.0 0.2 11.8 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF5559 PF17714.1 GBG87881.1 - 0.43 10.4 1.7 0.76 9.6 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5559) RVT_1 PF00078.27 GBG87882.1 - 2.7e-28 99.0 0.0 4.6e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG87882.1 - 5.6e-23 81.2 0.3 2.5e-22 79.2 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87882.1 - 9.1e-16 57.7 0.1 3.3e-15 55.9 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG87882.1 - 4.8e-13 49.0 0.1 2.6e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87882.1 - 4e-12 46.4 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG87882.1 - 0.00017 21.7 0.1 0.00036 20.7 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG87883.1 - 0.02 15.2 0.3 0.098 12.9 0.0 2.2 2 1 1 3 3 3 0 Retrotransposon gag protein bZIP_2 PF07716.15 GBG87884.1 - 0.022 14.8 3.0 0.07 13.2 3.0 1.9 1 0 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.18 GBG87884.1 - 0.038 14.2 1.2 0.089 13.0 1.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GBG87884.1 - 0.079 13.1 0.9 0.23 11.6 0.9 1.8 1 0 0 1 1 1 0 bZIP transcription factor XhlA PF10779.9 GBG87884.1 - 0.13 12.4 0.6 0.98 9.7 0.3 2.5 2 0 0 2 2 2 0 Haemolysin XhlA DUF2385 PF09539.10 GBG87884.1 - 0.17 12.4 0.3 0.72 10.4 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) ZapB PF06005.12 GBG87884.1 - 0.34 11.4 4.0 1.1 9.7 4.0 1.9 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 GBG87884.1 - 1.1 9.1 5.8 0.12 12.1 1.2 1.8 2 0 0 2 2 2 0 Septum formation initiator GvpL_GvpF PF06386.11 GBG87884.1 - 9.2 6.1 10.6 0.74 9.7 5.4 1.8 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_1 PF00170.21 GBG87885.1 - 2.2e-10 40.5 14.2 2.2e-10 40.5 14.2 2.0 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GBG87885.1 - 6.1e-05 23.0 13.4 6.1e-05 23.0 13.4 2.7 2 1 1 3 3 3 1 Basic region leucine zipper zf-CCHC PF00098.23 GBG87886.1 - 1.6e-06 27.9 4.3 2.8e-06 27.1 4.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Integrase_Zn PF02022.19 GBG87886.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Integrase Zinc binding domain Myc-LZ PF02344.15 GBG87886.1 - 0.26 11.4 0.1 0.26 11.4 0.1 3.5 3 0 0 3 3 3 0 Myc leucine zipper domain Holin_BhlA PF10960.8 GBG87886.1 - 6.2 6.9 7.0 0.78 9.8 1.5 2.4 2 0 0 2 2 2 0 BhlA holin family zf-CCHC PF00098.23 GBG87887.1 - 0.00011 22.1 1.4 0.00017 21.5 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG87887.1 - 0.11 12.4 0.7 0.3 11.0 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle MCC-bdg_PDZ PF10506.9 GBG87888.1 - 0.052 13.6 1.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome PapB PF03333.13 GBG87889.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein Cucumo_2B PF03263.13 GBG87890.1 - 0.052 14.0 0.3 0.063 13.7 0.3 1.1 1 0 0 1 1 1 0 Cucumovirus protein 2B DWNN PF08783.11 GBG87890.1 - 0.094 13.0 0.1 0.12 12.7 0.1 1.1 1 0 0 1 1 1 0 DWNN domain HEAT_2 PF13646.6 GBG87893.1 - 2e-31 108.2 20.3 3.9e-13 49.6 0.8 4.1 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 GBG87893.1 - 2.3e-23 80.4 18.0 1.6e-05 25.1 0.0 7.1 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 GBG87893.1 - 5.4e-09 35.5 6.7 0.028 14.7 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 GBG87893.1 - 5.9e-06 26.7 11.9 3.7 8.1 0.0 6.5 7 0 0 7 7 7 3 HEAT-like repeat Arm PF00514.23 GBG87893.1 - 0.00076 19.4 4.1 0.93 9.6 0.0 4.6 3 1 2 5 5 5 1 Armadillo/beta-catenin-like repeat IFRD PF05004.13 GBG87893.1 - 0.078 12.1 0.1 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Peptidase_S78 PF04586.17 GBG87893.1 - 0.11 12.7 0.0 29 4.8 0.0 3.0 2 2 2 4 4 4 0 Caudovirus prohead serine protease PUB_1 PF18486.1 GBG87893.1 - 8.9 6.3 13.1 1.7 8.6 1.2 4.4 3 2 2 5 5 5 0 PNGase/UBA- or UBX-containing domain gag-asp_proteas PF13975.6 GBG87894.1 - 1.1e-05 25.9 0.1 3e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG87894.1 - 1.3e-05 25.7 0.1 3.5e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG87894.1 - 0.0023 17.7 0.1 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG87894.1 - 0.24 11.6 2.4 0.49 10.6 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle NAD_binding_1 PF00175.21 GBG87895.1 - 7.2e-15 55.6 0.0 1.9e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GBG87895.1 - 2.6e-05 24.5 0.0 4.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GBG87895.1 - 0.00064 19.9 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4683 PF15735.5 GBG87895.1 - 0.37 10.4 7.9 0.51 9.9 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) DUF4746 PF15928.5 GBG87895.1 - 1.7 8.0 14.7 2.6 7.4 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4551 PF15087.6 GBG87895.1 - 3 6.6 6.3 4.2 6.1 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NAD_binding_1 PF00175.21 GBG87896.1 - 3.9e-13 50.0 0.0 1e-12 48.6 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Nop14 PF04147.12 GBG87896.1 - 0.91 7.7 6.3 0.97 7.6 6.3 1.0 1 0 0 1 1 1 0 Nop14-like family NAD_binding_1 PF00175.21 GBG87898.1 - 6.3e-18 65.4 0.1 2.2e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CDC45 PF02724.14 GBG87898.1 - 0.78 8.0 12.8 1 7.5 11.2 1.8 2 0 0 2 2 2 0 CDC45-like protein SPEG_u2 PF16650.5 GBG87899.1 - 2.4 8.4 9.3 44 4.3 0.1 3.5 3 0 0 3 3 3 0 Unstructured region on SPEG complex protein FAD_binding_6 PF00970.24 GBG87900.1 - 3.9e-24 84.9 0.0 5.1e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GBG87900.1 - 1.5e-05 25.6 0.1 2.4e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GBG87900.1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Creatinase_N PF01321.18 GBG87901.1 - 0.083 13.6 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain SRP-alpha_N PF04086.13 GBG87901.1 - 0.11 12.3 10.5 0.035 14.1 7.4 1.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Suf PF05843.14 GBG87901.1 - 0.56 10.1 3.5 0.96 9.4 3.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RVT_1 PF00078.27 GBG87902.1 - 3.9e-22 78.9 0.0 6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dpy-30 PF05186.13 GBG87903.1 - 2.5e-11 43.1 0.0 3.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Dpy-30 PF05186.13 GBG87904.1 - 2.1e-11 43.3 0.0 3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif F-box-like PF12937.7 GBG87907.1 - 0.0015 18.4 0.1 0.0039 17.0 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GBG87907.1 - 0.0072 16.2 0.2 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 GBG87907.1 - 0.028 14.8 1.4 7.7 7.1 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) RVT_1 PF00078.27 GBG87910.1 - 2.8e-28 98.9 0.0 4.8e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lin0512_fam PF09585.10 GBG87910.1 - 0.058 13.4 0.4 9 6.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) PDEase_II PF02112.15 GBG87910.1 - 0.082 12.0 0.3 0.12 11.4 0.3 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II p47_phox_C PF08944.11 GBG87910.1 - 7.6 6.0 7.1 14 5.2 4.2 2.7 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain CYSTM PF12734.7 GBG87911.1 - 0.00024 21.3 17.1 0.00024 21.3 17.1 4.1 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance PEMT PF04191.13 GBG87912.1 - 8.6e-08 32.5 0.3 8.6e-08 32.5 0.3 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 GBG87912.1 - 4.1e-07 30.3 1.0 2e-06 28.1 0.9 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 GBG87912.1 - 0.0076 15.1 0.2 0.016 14.0 0.2 1.5 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family LCD1 PF09798.9 GBG87913.1 - 0.31 9.5 6.0 0.34 9.4 6.0 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein ACCA PF03255.14 GBG87914.1 - 0.028 14.3 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DDE_Tnp_4 PF13359.6 GBG87916.1 - 1.1e-06 28.4 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG87916.1 - 0.0064 16.1 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DUF3791 PF12668.7 GBG87917.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Goodbye PF17109.5 GBG87918.1 - 0.026 15.0 0.4 2.7 8.5 0.0 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain FERM_f0 PF16511.5 GBG87918.1 - 2 8.8 14.8 60 4.0 0.8 5.1 1 1 4 5 5 5 0 N-terminal or F0 domain of Talin-head FERM TcdA_TcdB PF12919.7 GBG87920.1 - 0.0067 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain zf-CCHC_2 PF13696.6 GBG87921.1 - 4.9e-05 23.0 4.1 4.9e-05 23.0 4.1 1.9 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC PF00098.23 GBG87921.1 - 9.3e-05 22.3 1.8 0.00017 21.5 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle ParB PF08775.10 GBG87921.1 - 0.55 10.7 5.6 0.82 10.2 0.0 3.0 3 0 0 3 3 3 0 ParB family DUF659 PF04937.15 GBG87922.1 - 4.5e-23 81.8 0.0 7.7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG87922.1 - 0.12 12.2 0.1 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region TcdA_TcdB PF12919.7 GBG87923.1 - 0.078 12.3 0.1 0.55 9.5 0.0 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Senescence_reg PF04520.13 GBG87925.1 - 4.6e-16 60.1 5.8 2e-15 58.1 0.0 2.4 2 0 0 2 2 2 1 Senescence regulator Chorion_3 PF05387.11 GBG87926.1 - 0.5 10.0 2.1 3.1 7.4 0.1 2.4 2 1 0 2 2 2 0 Chorion family 3 Lin-8 PF03353.15 GBG87928.1 - 7.7 6.0 11.2 15 5.1 11.2 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLD3 PF08639.10 GBG87929.1 - 5.7e-05 22.1 4.6 6.5e-05 21.9 4.6 1.0 1 0 0 1 1 1 1 DNA replication regulator SLD3 Herpes_BLRF2 PF05812.12 GBG87929.1 - 0.59 10.3 8.6 0.12 12.5 4.6 2.1 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein Flag1_repress PF03614.13 GBG87930.1 - 0.035 13.9 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Nbl1_Borealin_N PF10444.9 GBG87930.1 - 1.6 8.4 4.2 1.1 8.9 0.2 2.6 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal CLIP1_ZNF PF16641.5 GBG87931.1 - 0.0036 17.1 13.9 0.0058 16.5 1.6 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle zf-CCHC_4 PF14392.6 GBG87931.1 - 1.6 8.6 8.9 6.5 6.6 1.3 2.7 1 1 1 2 2 2 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG87932.1 - 7.6e-19 67.6 0.1 7.6e-19 67.6 0.1 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG87932.1 - 7.4e-13 48.7 0.1 2.3e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG87932.1 - 1.5e-11 44.5 1.7 3e-11 43.5 1.7 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87932.1 - 2e-05 24.5 0.2 3.7e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Dynactin_p22 PF07426.11 GBG87932.1 - 0.026 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Dynactin subunit p22 DAHP_snth_FXD PF18152.1 GBG87932.1 - 0.19 11.6 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain DUF4210 PF13915.6 GBG87933.1 - 0.1 13.2 0.1 0.17 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4210) DnaJ PF00226.31 GBG87934.1 - 1.5e-15 57.0 2.1 2.7e-15 56.2 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 GBG87934.1 - 1.2e-13 50.6 0.0 2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4378 PF14309.6 GBG87935.1 - 2.1e-28 99.8 0.0 2.1e-28 99.8 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4378) DUF4378 PF14309.6 GBG87936.1 - 2.1e-28 99.8 0.0 2.1e-28 99.8 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4378) Integrase_H2C2 PF17921.1 GBG87937.1 - 4.8e-16 58.6 0.1 9.7e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG87937.1 - 6.1e-12 45.8 0.0 1.6e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG87937.1 - 0.085 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RRM_1 PF00076.22 GBG87938.1 - 3.1e-08 33.3 0.1 1e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GBG87939.1 - 3.3e-08 33.2 0.1 1e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.24 GBG87940.1 - 5.7e-22 78.5 0.0 1.5e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GBG87940.1 - 0.024 14.8 0.1 0.05 13.7 0.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 GBG87940.1 - 0.031 14.6 0.2 0.087 13.1 0.2 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Syja_N PF02383.18 GBG87940.1 - 0.089 12.1 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 SacI homology domain TFIID-31kDa PF02291.15 GBG87940.1 - 0.23 11.5 0.6 0.58 10.2 0.6 1.5 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_transf_41 PF13844.6 GBG87941.1 - 3.3e-145 484.1 0.2 3.7e-72 243.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 GBG87941.1 - 2.7e-98 318.1 34.7 1.4e-10 40.6 0.2 13.4 13 0 0 13 13 13 13 Tetratricopeptide repeat TPR_11 PF13414.6 GBG87941.1 - 1.7e-78 258.0 32.7 1e-11 44.3 1.2 11.4 5 3 6 11 11 11 11 TPR repeat TPR_2 PF07719.17 GBG87941.1 - 1.3e-75 243.5 29.0 6.1e-08 32.2 0.2 13.5 13 0 0 13 13 13 13 Tetratricopeptide repeat TPR_8 PF13181.6 GBG87941.1 - 4.5e-64 207.4 22.0 1.4e-06 28.1 0.0 13.5 14 0 0 14 14 13 12 Tetratricopeptide repeat TPR_17 PF13431.6 GBG87941.1 - 2.2e-61 199.9 35.3 3e-06 27.2 0.1 14.4 14 0 0 14 14 14 12 Tetratricopeptide repeat TPR_7 PF13176.6 GBG87941.1 - 5.5e-41 135.6 19.1 0.001 18.9 0.3 12.9 12 1 0 13 13 13 8 Tetratricopeptide repeat TPR_12 PF13424.6 GBG87941.1 - 5.3e-39 132.4 28.6 6.7e-10 39.1 0.8 9.2 3 3 5 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.6 GBG87941.1 - 3.8e-35 120.3 11.9 1.3e-07 32.2 0.3 8.7 4 3 3 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 GBG87941.1 - 5.8e-35 117.0 13.5 1.3e-05 25.6 0.3 11.3 3 3 9 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 GBG87941.1 - 4e-28 97.7 21.5 3.7e-07 30.5 2.4 7.9 3 2 2 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 GBG87941.1 - 2.4e-20 71.7 42.9 0.00034 20.4 0.1 13.1 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_9 PF13371.6 GBG87941.1 - 2.4e-18 66.0 17.8 5.6e-05 23.2 0.6 7.5 4 2 4 9 9 9 6 Tetratricopeptide repeat NARP1 PF12569.8 GBG87941.1 - 3.6e-14 52.6 1.6 0.00061 18.8 0.0 5.2 2 2 3 5 5 5 4 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 GBG87941.1 - 5.9e-12 45.4 16.0 0.014 16.0 0.1 10.4 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_15 PF13429.6 GBG87941.1 - 3.9e-08 32.8 3.3 1.3 8.2 0.1 5.7 1 1 2 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 GBG87941.1 - 1.1e-06 29.2 5.6 0.29 11.6 0.0 5.1 3 2 1 5 5 5 2 Bacterial transcriptional activator domain EST1_DNA_bind PF10373.9 GBG87941.1 - 7.1e-06 25.7 16.2 0.0039 16.7 0.7 6.0 7 0 0 7 7 7 2 Est1 DNA/RNA binding domain FAT PF02259.23 GBG87941.1 - 1.1e-05 24.9 0.0 1.6 7.8 0.0 4.9 1 1 2 4 4 4 1 FAT domain Fis1_TPR_C PF14853.6 GBG87941.1 - 1.7e-05 24.8 13.4 0.11 12.6 2.0 6.7 6 1 1 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 GBG87941.1 - 2.6e-05 24.4 5.6 15 6.6 0.1 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG87941.1 - 3.6e-05 23.9 21.4 0.0018 18.4 1.3 5.5 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 GBG87941.1 - 0.00012 21.6 6.7 0.17 11.2 0.1 4.3 1 1 4 5 5 5 2 MalT-like TPR region TPR_20 PF14561.6 GBG87941.1 - 0.0011 19.3 1.8 2.1 8.7 0.0 5.3 4 2 3 7 7 7 1 Tetratricopeptide repeat PPR PF01535.20 GBG87941.1 - 0.0013 18.8 2.7 14 6.2 0.0 6.5 8 0 0 8 8 6 0 PPR repeat TPR_21 PF09976.9 GBG87941.1 - 0.005 16.6 1.1 6.9 6.3 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 GBG87941.1 - 0.077 13.0 0.1 0.34 10.9 0.1 2.1 1 0 0 1 1 1 0 Putative TPR-like repeat Sec16_C PF12931.7 GBG87941.1 - 0.086 12.5 0.3 14 5.2 0.0 3.2 2 1 1 3 3 3 0 Sec23-binding domain of Sec16 ChAPs PF09295.10 GBG87941.1 - 0.1 11.6 1.5 4.6 6.1 0.1 3.5 3 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Alkyl_sulf_dimr PF14863.6 GBG87941.1 - 0.35 11.3 1.4 73 3.8 0.0 3.8 5 0 0 5 5 3 0 Alkyl sulfatase dimerisation MIT PF04212.18 GBG87941.1 - 2.9 8.0 22.3 41 4.4 0.4 7.8 9 1 0 9 9 7 0 MIT (microtubule interacting and transport) domain CHAT PF12770.7 GBG87945.1 - 1.9e-25 89.9 0.1 5.4e-13 49.0 0.0 3.5 3 1 0 3 3 3 2 CHAT domain CENP-B_dimeris PF09026.10 GBG87945.1 - 0.18 12.2 24.5 1.8 9.0 15.8 3.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3246 PF11596.8 GBG87945.1 - 3.7 6.9 19.3 0.16 11.4 10.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) F-box-like PF12937.7 GBG87946.1 - 2.1e-05 24.3 0.1 3.9e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG87946.1 - 0.0021 17.9 0.1 0.0054 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain Nop14 PF04147.12 GBG87946.1 - 0.46 8.6 10.8 0.64 8.2 10.8 1.2 1 0 0 1 1 1 0 Nop14-like family Mrr_cat PF04471.12 GBG87947.1 - 0.061 13.4 0.0 0.7 9.9 0.0 2.6 2 0 0 2 2 2 0 Restriction endonuclease DUF5323 PF17257.2 GBG87947.1 - 0.24 11.3 2.7 0.47 10.3 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5323) Goodbye PF17109.5 GBG87949.1 - 0.076 13.5 0.6 2 8.9 0.1 2.5 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain RT_RNaseH PF17917.1 GBG87950.1 - 3.9e-19 68.9 0.0 1.1e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87950.1 - 4.1e-19 68.4 0.6 9.9e-19 67.2 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG87950.1 - 1.3e-17 63.7 0.0 2.6e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ATE_N PF04376.13 GBG87950.1 - 0.015 15.6 0.6 0.15 12.5 0.0 2.6 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus zf-H2C2 PF09337.10 GBG87950.1 - 0.065 13.5 0.2 0.15 12.3 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG87950.1 - 0.23 11.6 6.1 0.034 14.2 1.8 1.9 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG87951.1 - 2e-26 91.9 0.0 3.7e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87951.1 - 3.8e-25 88.2 0.0 6.9e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG87951.1 - 3.1e-13 49.8 0.1 4.3e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3807 PF12720.7 GBG87951.1 - 0.13 12.6 16.2 0.22 11.8 16.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SDA1 PF05285.12 GBG87951.1 - 0.66 9.3 29.8 0.94 8.8 29.8 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG87951.1 - 2.5 7.4 26.7 3.5 6.9 26.7 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GBG87951.1 - 2.7 7.6 18.7 4.3 7.0 18.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2950 PF11453.8 GBG87954.1 - 0.8 8.8 9.0 1.3 8.1 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) F-box-like PF12937.7 GBG87955.1 - 3.7e-05 23.5 0.1 7.6e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG87955.1 - 0.018 14.9 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 F-box domain RT_RNaseH PF17917.1 GBG87956.1 - 3.8e-22 78.6 0.1 9.9e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG87956.1 - 4.2e-22 78.1 0.0 1.2e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase WTX PF09422.10 GBG87956.1 - 0.014 14.5 2.1 0.024 13.7 2.1 1.3 1 0 0 1 1 1 0 WTX protein Retrotrans_gag PF03732.17 GBG87956.1 - 0.13 12.6 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG87956.1 - 7.9 6.6 9.8 0.76 9.9 4.6 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation Sel1 PF08238.12 GBG87957.1 - 1.4e-06 28.7 13.1 0.11 13.2 0.0 6.4 7 0 0 7 7 7 3 Sel1 repeat Nop14 PF04147.12 GBG87958.1 - 0.47 8.6 25.0 0.53 8.4 25.0 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG87958.1 - 0.55 9.6 29.2 0.61 9.4 29.2 1.0 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG87958.1 - 7.1 5.1 24.7 10 4.6 24.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PTPRCAP PF15713.5 GBG87958.1 - 9.4 6.5 15.0 12 6.1 15.0 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated peroxidase PF00141.23 GBG87959.1 - 2.7e-46 158.1 0.1 3.4e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 Peroxidase peroxidase PF00141.23 GBG87960.1 - 2.3e-46 158.4 0.0 3.4e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase zf-CCHC PF00098.23 GBG87961.1 - 4.1e-08 32.9 1.2 4.1e-08 32.9 1.2 2.1 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG87961.1 - 1.7e-05 25.0 0.7 3.9e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG87961.1 - 0.02 14.7 2.7 0.043 13.6 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle peroxidase PF00141.23 GBG87962.1 - 1.3e-45 155.9 0.0 1.8e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase DUF659 PF04937.15 GBG87964.1 - 1.6e-09 37.8 0.0 2.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) peroxidase PF00141.23 GBG87965.1 - 3.9e-46 157.6 0.0 5.7e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Asp_protease_2 PF13650.6 GBG87966.1 - 2.6e-05 24.8 0.0 0.00017 22.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG87966.1 - 6.6e-05 23.1 0.1 0.0003 21.0 0.1 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG87966.1 - 0.00017 22.1 0.0 0.0006 20.3 0.0 2.0 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG87966.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG87966.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease CLZ PF16526.5 GBG87966.1 - 0.025 14.9 2.4 0.31 11.4 0.1 3.2 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ATG16 PF08614.11 GBG87966.1 - 0.11 12.7 8.7 0.63 10.2 0.2 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1465 PF07323.12 GBG87966.1 - 0.14 12.0 1.1 13 5.6 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1465) YPEB PF14620.6 GBG87966.1 - 0.15 11.4 0.5 0.23 10.8 0.5 1.2 1 0 0 1 1 1 0 YpeB sporulation Laminin_II PF06009.12 GBG87966.1 - 0.2 11.6 4.7 0.085 12.9 1.1 2.1 2 0 0 2 2 2 0 Laminin Domain II TolA_bind_tri PF16331.5 GBG87966.1 - 0.39 10.8 2.2 5.3 7.2 0.2 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation LPP PF04728.13 GBG87966.1 - 1.5 9.3 5.1 14 6.2 0.2 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 GBG87966.1 - 3.9 7.5 6.0 3.4 7.7 2.8 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus peroxidase PF00141.23 GBG87967.1 - 1.6e-43 149.1 0.0 2e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase DUF4702 PF15774.5 GBG87969.1 - 0.029 13.3 0.1 0.04 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) Dimer_Tnp_hAT PF05699.14 GBG87970.1 - 1.1e-07 31.5 0.1 2.2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UPF0561 PF10573.9 GBG87970.1 - 0.021 15.0 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 DGF-1_C PF11040.8 GBG87971.1 - 1.9 8.5 8.6 0.83 9.7 0.9 3.2 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Integrase_H2C2 PF17921.1 GBG87976.1 - 8.2e-13 48.2 0.2 1.5e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain SDA1 PF05285.12 GBG87976.1 - 0.00081 18.9 34.9 0.00081 18.9 34.9 2.1 2 0 0 2 2 2 1 SDA1 PPP4R2 PF09184.11 GBG87976.1 - 0.0046 16.6 28.1 0.0046 16.6 28.1 2.2 2 0 0 2 2 2 1 PPP4R2 Caldesmon PF02029.15 GBG87976.1 - 0.01 14.6 40.8 0.014 14.2 40.8 1.1 1 0 0 1 1 1 0 Caldesmon zf-H2C2 PF09337.10 GBG87976.1 - 0.18 12.1 0.1 0.29 11.4 0.1 1.3 1 0 0 1 1 1 0 H2C2 zinc finger DUF2828 PF11443.8 GBG87976.1 - 0.45 8.6 6.1 0.98 7.4 6.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Zip PF02535.22 GBG87976.1 - 0.63 9.2 10.9 0.9 8.7 10.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Tub_N PF16322.5 GBG87976.1 - 0.65 10.4 33.7 4 7.8 1.0 2.3 2 0 0 2 2 2 0 Tubby N-terminal Spore_coat_CotO PF14153.6 GBG87976.1 - 0.7 9.8 29.2 0.019 14.9 21.2 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Neur_chan_memb PF02932.16 GBG87976.1 - 5.1 7.1 7.9 10 6.1 7.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 GBG87976.1 - 8 6.2 32.3 1.3 8.8 25.4 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 GBG87976.1 - 8.4 5.0 18.4 0.74 8.5 13.9 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 GBG87976.1 - 9.4 5.0 15.5 22 3.7 15.5 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain peroxidase PF00141.23 GBG87978.1 - 4.1e-46 157.5 0.0 5.2e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase DUF3138 PF11336.8 GBG87979.1 - 0.71 8.4 3.7 1.1 7.8 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Topo_Zn_Ribbon PF08272.11 GBG87981.1 - 0.014 15.1 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVT_1 PF00078.27 GBG87982.1 - 1e-07 31.7 0.0 2.9e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 GBG87982.1 - 1.7e-06 27.8 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GBG87982.1 - 0.0017 17.9 0.1 0.0032 17.0 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 GBG87983.1 - 1.1e-05 25.2 3.5 2.5e-05 24.1 3.5 1.6 1 0 0 1 1 1 1 Zinc knuckle COMPASS-Shg1 PF05205.12 GBG87983.1 - 0.024 15.3 3.9 0.086 13.6 0.7 2.3 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 IATP PF04568.12 GBG87983.1 - 0.043 14.3 1.5 0.043 14.3 1.5 2.1 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP zf-CCHC_2 PF13696.6 GBG87983.1 - 1 9.2 3.7 0.29 11.0 0.6 1.8 2 0 0 2 2 2 0 Zinc knuckle LMBR1 PF04791.16 GBG87984.1 - 1.2 7.9 6.7 1.9 7.3 6.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RVT_1 PF00078.27 GBG87985.1 - 3.1e-07 30.1 0.0 7.4e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RuBisCO_small PF00101.20 GBG87988.1 - 6.6e-43 144.6 0.1 9.4e-43 144.1 0.1 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain Peptidase_C48 PF02902.19 GBG87991.1 - 1.7e-10 41.1 3.3 2.6e-09 37.3 3.3 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-CCHC PF00098.23 GBG87992.1 - 0.024 14.7 3.9 0.06 13.5 3.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG87992.1 - 0.051 13.9 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 GBG87992.1 - 0.075 12.8 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG87992.1 - 0.084 12.7 0.9 0.21 11.5 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Mito_carr PF00153.27 GBG87993.1 - 2.5e-33 113.8 4.4 1.1e-15 57.3 0.1 3.2 2 1 0 2 2 2 2 Mitochondrial carrier protein Asp_protease_2 PF13650.6 GBG87994.1 - 0.0026 18.4 0.0 0.0048 17.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG87994.1 - 0.0083 16.7 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG87994.1 - 0.0094 16.2 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG87995.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG87995.1 - 0.0055 17.0 0.1 0.032 14.5 0.0 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 GBG87995.1 - 0.63 9.9 2.1 1.3 8.9 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG87996.1 - 1.8e-33 115.9 0.1 8.2e-33 113.8 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG87996.1 - 6.9e-31 106.3 0.0 1.8e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG87996.1 - 4.9e-28 97.5 0.0 1.2e-27 96.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87996.1 - 2.2e-14 53.3 0.0 5.8e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG87996.1 - 0.00031 20.9 0.0 0.0013 18.9 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger HIP1_clath_bdg PF16515.5 GBG87996.1 - 0.0071 16.9 1.3 0.0071 16.9 1.3 2.3 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4495 PF14906.6 GBG87996.1 - 0.014 14.5 2.5 2 7.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4495) Rhamno_transf PF11316.8 GBG87996.1 - 0.034 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase CmlA_N PF18456.1 GBG87996.1 - 0.17 11.2 1.4 0.26 10.5 0.6 1.6 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain ALIX_LYPXL_bnd PF13949.6 GBG87996.1 - 0.23 10.7 4.0 0.23 10.7 0.7 2.2 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF2959 PF11172.8 GBG87996.1 - 0.45 10.6 2.5 9 6.4 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) FlxA PF14282.6 GBG87996.1 - 3.7 7.6 9.2 0.72 9.9 1.6 3.0 3 1 0 3 3 3 0 FlxA-like protein RT_RNaseH_2 PF17919.1 GBG87997.1 - 1.2e-28 99.1 0.0 1.9e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG87997.1 - 5e-19 68.2 0.3 1.1e-18 67.1 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG87997.1 - 1.3e-16 60.7 0.0 2.8e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG87997.1 - 1.6e-07 31.5 0.0 5.7e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG87997.1 - 0.0054 16.9 0.1 0.0054 16.9 0.1 2.1 2 0 0 2 2 2 1 H2C2 zinc finger FANCM-MHF_bd PF16783.5 GBG87999.1 - 5.2 7.2 9.5 0.25 11.4 2.6 2.3 1 1 2 3 3 3 0 FANCM to MHF binding domain DUF659 PF04937.15 GBG88000.1 - 1.2e-09 38.2 0.0 1.7e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88001.1 - 3.9e-10 39.4 0.1 9.9e-10 38.1 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TipE PF16972.5 GBG88001.1 - 3.4 6.7 4.3 6.2 5.9 4.3 1.3 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE RT_RNaseH_2 PF17919.1 GBG88002.1 - 3.5e-22 78.3 0.0 8.2e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88002.1 - 4.9e-22 78.2 0.1 1.4e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88002.1 - 2.8e-18 66.2 0.5 2.6e-17 63.1 0.1 2.8 3 1 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG88002.1 - 0.0013 19.0 0.0 0.41 10.9 0.0 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG88002.1 - 0.0018 18.3 0.0 0.0071 16.4 0.0 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG88003.1 - 2.2e-67 224.0 3.5 1.1e-29 102.7 0.1 4.2 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88003.1 - 9.5e-64 214.9 0.4 1.1e-31 110.1 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88003.1 - 1.6e-52 175.7 0.1 1.5e-26 92.3 0.0 4.0 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88003.1 - 1.7e-20 72.9 6.8 2.2e-20 72.5 0.2 3.2 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88003.1 - 0.031 14.5 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG88004.1 - 7.7e-25 86.8 0.0 1.6e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88004.1 - 2.4e-23 82.4 0.0 9.2e-23 80.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88004.1 - 2.3e-12 46.8 0.0 6.3e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG88004.1 - 0.004 17.7 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG88004.1 - 0.0069 16.6 0.2 0.024 14.9 0.2 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG88004.1 - 0.029 15.0 0.0 0.066 13.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG88004.1 - 0.19 11.6 0.1 0.54 10.1 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG88007.1 - 7.6e-28 97.5 0.5 1.4e-27 96.7 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88007.1 - 8.8e-23 80.6 0.0 1.6e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88007.1 - 1.6e-21 76.2 0.0 4.1e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88007.1 - 1.3e-11 44.4 2.2 3.2e-11 43.2 2.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG88009.1 - 1.1e-41 141.0 0.0 9.5e-27 93.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88009.1 - 5e-40 136.0 0.0 7.8e-19 67.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88009.1 - 1.7e-35 122.6 0.1 3.6e-35 121.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88009.1 - 1.3e-12 47.6 0.2 3.3e-12 46.3 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88009.1 - 1.5e-12 47.7 0.0 3.7e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain AJAP1_PANP_C PF15298.6 GBG88009.1 - 3.3 7.9 7.2 11 6.2 0.3 2.4 2 0 0 2 2 2 0 AJAP1/PANP C-terminus RT_RNaseH_2 PF17919.1 GBG88010.1 - 8e-28 96.4 0.0 1.7e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88010.1 - 2.5e-24 85.5 0.0 5.2e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88010.1 - 5e-15 55.4 0.1 1.2e-14 54.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88010.1 - 5.8e-12 45.8 0.0 1.4e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG88010.1 - 2.2e-10 40.4 0.0 5.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG88010.1 - 0.00038 20.6 0.0 0.00095 19.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger tRNA_lig_CPD PF08302.11 GBG88010.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain RT_RNaseH PF17917.1 GBG88011.1 - 2.4e-27 95.3 0.1 4.5e-27 94.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88011.1 - 1.9e-22 79.2 0.0 3.4e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88011.1 - 1.2e-13 50.9 0.0 2.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88011.1 - 0.069 13.4 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG88011.1 - 0.97 9.6 2.4 2.6 8.3 2.4 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG88012.1 - 2.5e-15 56.6 0.0 4.3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG88013.1 - 3.2e-23 82.3 0.0 5e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG88014.1 - 0.0043 16.6 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Virul_fac_BrkB PF03631.15 GBG88015.1 - 0.043 13.4 37.1 0.28 10.8 11.1 3.3 3 0 0 3 3 3 0 Virulence factor BrkB DUF4013 PF13197.6 GBG88015.1 - 0.13 12.1 46.0 0.096 12.5 13.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4013) DUF898 PF05987.13 GBG88015.1 - 1.3 8.0 43.9 0.11 11.6 8.5 3.1 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF898) DHHC PF01529.20 GBG88015.1 - 2.1 8.5 20.1 2.5 8.2 1.9 3.3 2 1 2 4 4 4 0 DHHC palmitoyltransferase TrbL PF04610.14 GBG88015.1 - 3.9 7.2 44.8 0.47 10.2 1.9 5.1 5 0 0 5 5 5 0 TrbL/VirB6 plasmid conjugal transfer protein PRTP PF01366.18 GBG88016.1 - 0.045 11.8 2.0 0.051 11.6 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Prothymosin PF03247.14 GBG88016.1 - 0.1 13.0 14.0 0.15 12.6 14.0 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF2868 PF11067.8 GBG88016.1 - 1.9 8.0 4.6 2.2 7.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) CDC45 PF02724.14 GBG88016.1 - 4 5.6 7.7 4 5.6 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein rve PF00665.26 GBG88018.1 - 5.2e-12 46.0 0.0 1.7e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG88019.1 - 4.3e-30 104.9 0.3 1.5e-29 103.1 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88019.1 - 5.1e-23 81.0 0.1 2e-20 72.7 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88019.1 - 1.6e-20 73.3 0.2 1e-19 70.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88019.1 - 3.4e-20 71.9 0.1 8.5e-20 70.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88019.1 - 4.3e-09 36.6 0.0 1.6e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG88019.1 - 4.7e-08 32.9 0.0 9.8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88019.1 - 7.3e-08 33.0 0.0 3.8e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88019.1 - 1.6e-06 28.6 0.0 6.9e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88019.1 - 0.0071 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG88019.1 - 0.037 14.2 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG88019.1 - 0.089 13.1 3.8 0.3 11.4 0.0 3.7 2 1 1 3 3 3 0 Retrotransposon gag protein AMP-binding_C_2 PF14535.6 GBG88019.1 - 1.4 9.3 0.0 1.4 9.3 0.0 5.0 6 0 0 6 6 6 0 AMP-binding enzyme C-terminal domain MMU163 PF17119.5 GBG88021.1 - 8.6 5.4 9.1 9.8 5.3 9.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis BUD22 PF09073.10 GBG88022.1 - 0.47 9.8 70.5 0.55 9.5 70.5 1.1 1 0 0 1 1 1 0 BUD22 RNase_PH PF01138.21 GBG88023.1 - 2.3e-38 131.7 0.6 4.6e-38 130.7 0.1 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 MazG-like PF12643.7 GBG88023.1 - 1.8e-09 37.7 0.0 3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 MazG-like family RNase_PH_C PF03725.15 GBG88023.1 - 3.7e-07 30.1 0.0 6.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MazG PF03819.17 GBG88023.1 - 1.9e-05 24.8 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain UPF0193 PF05250.11 GBG88023.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) MoaC PF01967.21 GBG88023.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 MoaC family zf-CCHC_6 PF15288.6 GBG88024.1 - 0.017 14.9 1.7 0.052 13.4 1.7 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG88024.1 - 0.029 14.1 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Zinc knuckle FTA4 PF13093.6 GBG88024.1 - 0.035 14.0 1.4 0.069 13.0 1.4 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CinA PF02464.17 GBG88024.1 - 0.54 9.8 5.3 1.3 8.5 5.3 1.6 1 0 0 1 1 1 0 Competence-damaged protein RT_RNaseH_2 PF17919.1 GBG88025.1 - 4e-33 113.4 0.1 3.8e-32 110.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88025.1 - 8.2e-31 106.4 0.2 2.9e-30 104.7 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88025.1 - 8.2e-29 100.7 0.1 1.5e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88025.1 - 5.1e-19 68.1 0.1 1e-18 67.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88025.1 - 0.029 14.6 0.1 0.11 12.7 0.1 2.0 1 0 0 1 1 1 0 H2C2 zinc finger IHABP4_N PF16174.5 GBG88025.1 - 2.6 8.6 9.2 4.9 7.7 9.2 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal MSP1_C PF07462.11 GBG88025.1 - 3.3 6.3 4.9 5.6 5.5 4.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RVT_1 PF00078.27 GBG88026.1 - 7.9e-19 68.1 0.1 1.4e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG88026.1 - 0.00045 20.0 0.0 0.00096 18.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88026.1 - 0.0015 19.0 0.0 0.0053 17.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88026.1 - 0.0036 17.9 0.0 0.012 16.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG88026.1 - 0.0061 16.8 0.9 0.1 12.9 0.0 3.4 3 0 0 3 3 3 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG88026.1 - 0.093 12.8 0.0 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase CLZ PF16526.5 GBG88026.1 - 0.68 10.3 8.1 0.27 11.6 0.8 3.7 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3138 PF11336.8 GBG88027.1 - 2.1 6.8 3.3 2.4 6.6 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) REV PF00424.18 GBG88027.1 - 3.6 7.7 8.5 0.32 11.1 0.3 2.5 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) YtxH PF12732.7 GBG88028.1 - 0.038 14.5 0.0 0.092 13.3 0.0 1.7 1 0 0 1 1 1 0 YtxH-like protein DUF3641 PF12345.8 GBG88029.1 - 4.3e-53 179.0 0.0 7.2e-53 178.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 GBG88029.1 - 2.1e-09 38.0 0.0 3.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GBG88029.1 - 0.0074 16.6 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain rve PF00665.26 GBG88030.1 - 2.8e-14 53.3 0.0 9.1e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG88030.1 - 0.00026 20.6 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88030.1 - 0.0031 17.6 2.0 0.0083 16.2 2.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88030.1 - 0.03 14.5 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 H2C2 zinc finger PPP4R2 PF09184.11 GBG88030.1 - 0.069 12.7 4.9 0.1 12.2 4.9 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GBG88030.1 - 0.2 9.8 12.0 0.25 9.5 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG88030.1 - 0.35 9.1 11.5 0.5 8.6 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG88030.1 - 1.4 8.3 12.8 1.8 7.9 12.8 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 GBG88030.1 - 1.6 8.6 9.1 2.7 7.8 9.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Spore_coat_CotO PF14153.6 GBG88030.1 - 2.1 8.2 7.8 3.4 7.5 7.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Astro_capsid_p PF12226.8 GBG88030.1 - 2.8 7.0 9.7 4.1 6.5 9.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RRN3 PF05327.11 GBG88030.1 - 3.8 6.0 4.8 5.3 5.5 4.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SspB PF04386.13 GBG88030.1 - 4.2 7.2 6.9 8.3 6.3 6.9 1.4 1 0 0 1 1 1 0 Stringent starvation protein B Pes-10 PF07149.11 GBG88030.1 - 5.1 6.0 13.7 7.7 5.5 13.7 1.2 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 GBG88030.1 - 6.6 4.7 16.5 8.8 4.3 16.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 GBG88031.1 - 0.59 9.7 6.9 1.7 8.2 0.6 3.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Agarase_CBM PF17992.1 GBG88032.1 - 0.21 11.1 26.1 14 5.2 0.5 10.4 8 3 3 11 11 11 0 Agarase CBM like domain DDE_Tnp_4 PF13359.6 GBG88033.1 - 8.2e-25 87.3 0.0 1.2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88033.1 - 4.6e-12 46.0 0.0 6.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG88034.1 - 7.3e-05 23.1 3.1 0.00054 20.3 1.3 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Tropomyosin PF00261.20 GBG88034.1 - 0.023 14.0 0.6 3.4 7.0 0.2 2.2 2 0 0 2 2 2 0 Tropomyosin WBP-1 PF11669.8 GBG88034.1 - 0.18 12.4 0.0 0.48 11.1 0.0 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 RT_RNaseH_2 PF17919.1 GBG88035.1 - 8e-44 147.8 0.0 3.1e-27 94.5 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG88035.1 - 6.1e-40 136.5 0.0 2.6e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease RT_RNaseH PF17917.1 GBG88035.1 - 1.8e-30 105.3 0.0 1.5e-23 83.1 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88035.1 - 1.7e-25 89.8 0.1 3e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plant_tran PF04827.14 GBG88035.1 - 1.9e-16 60.3 0.0 3.9e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Plant transposon protein Chromo PF00385.24 GBG88035.1 - 5e-11 42.3 0.0 1.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG88035.1 - 3.7e-10 40.0 0.6 8.9e-10 38.8 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_1 PF01609.21 GBG88035.1 - 0.0092 15.7 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Transposase DDE domain AP3D1 PF06375.11 GBG88035.1 - 6.7 6.9 12.0 12 6.1 12.0 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4192 PF13830.6 GBG88037.1 - 0.15 12.1 0.2 0.19 11.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) NB-ARC PF00931.22 GBG88038.1 - 7.1e-28 97.5 0.0 1.2e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain LRR_8 PF13855.6 GBG88038.1 - 3.6e-24 84.3 48.1 5.5e-06 26.1 0.1 12.0 7 6 3 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 GBG88038.1 - 3.1e-17 62.4 46.9 0.001 19.4 0.4 12.3 8 5 4 13 13 13 6 Leucine Rich repeats (2 copies) Pou PF00157.17 GBG88038.1 - 0.019 14.9 0.1 0.16 12.0 0.0 2.5 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain ATP-synt_ab PF00006.25 GBG88038.1 - 0.028 14.1 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 GBG88038.1 - 0.036 14.3 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG88038.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 GBG88039.1 - 7e-28 97.5 0.0 1.2e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain LRR_8 PF13855.6 GBG88039.1 - 3.1e-24 84.5 48.0 5.4e-06 26.1 0.1 12.0 7 6 3 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 GBG88039.1 - 2.3e-17 62.8 46.6 0.001 19.4 0.4 12.3 8 5 4 13 13 13 6 Leucine Rich repeats (2 copies) Pou PF00157.17 GBG88039.1 - 0.019 14.9 0.1 0.15 12.0 0.0 2.5 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain ATP-synt_ab PF00006.25 GBG88039.1 - 0.028 14.1 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 GBG88039.1 - 0.036 14.4 0.0 0.098 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG88039.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PDEase_II PF02112.15 GBG88040.1 - 0.047 12.8 0.4 0.064 12.4 0.4 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II DUF659 PF04937.15 GBG88041.1 - 4e-18 65.7 0.0 7.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG88042.1 - 2.5e-33 114.1 0.0 7.1e-33 112.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88042.1 - 1.6e-29 102.3 0.0 2.7e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88042.1 - 2e-15 57.0 0.1 3e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88043.1 - 8.5e-34 115.6 0.0 2.2e-33 114.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88043.1 - 5.2e-30 103.8 0.0 8.3e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88043.1 - 7.1e-16 58.4 0.1 1e-15 57.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_His PF13393.6 GBG88043.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF2249 PF10006.9 GBG88043.1 - 0.11 12.4 0.1 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) SIR2 PF02146.17 GBG88044.1 - 3.6e-26 92.1 0.0 2.5e-18 66.7 0.0 2.2 2 0 0 2 2 2 2 Sir2 family TF_Zn_Ribbon PF08271.12 GBG88044.1 - 0.0027 17.2 0.6 0.0096 15.4 0.5 1.9 1 1 1 2 2 2 1 TFIIB zinc-binding ADK_lid PF05191.14 GBG88044.1 - 0.059 13.4 0.4 0.22 11.5 0.4 2.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid Med16 PF11635.8 GBG88044.1 - 0.085 10.8 0.2 0.11 10.4 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 zinc_ribbon_15 PF17032.5 GBG88044.1 - 0.16 12.7 0.6 0.78 10.5 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon family zf-ribbon_3 PF13248.6 GBG88044.1 - 0.19 11.2 0.7 5.1 6.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 GBG88044.1 - 0.32 10.9 2.9 0.99 9.4 0.2 2.6 1 1 1 2 2 2 0 Putative transposase DNA-binding domain COR PF16095.5 GBG88045.1 - 1.6e-12 47.7 0.1 8.4e-11 42.0 0.0 2.6 3 0 0 3 3 3 1 C-terminal of Roc, COR, domain Roc PF08477.13 GBG88045.1 - 3.4e-09 37.0 0.0 6.9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GBG88045.1 - 0.0005 19.7 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GBG88045.1 - 0.00097 19.2 0.0 0.0027 17.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 GBG88045.1 - 0.034 13.6 0.0 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 GBG88045.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 GBG88046.1 - 2.3e-32 112.2 0.0 4.1e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain LRR_4 PF12799.7 GBG88046.1 - 2e-06 28.1 15.0 0.0063 16.9 0.3 6.2 5 1 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG88046.1 - 2.9e-06 26.9 21.1 0.021 14.5 3.7 5.1 5 2 3 8 8 8 4 Leucine rich repeat NACHT PF05729.12 GBG88046.1 - 0.00036 20.5 0.7 0.0027 17.6 0.1 2.8 3 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 GBG88046.1 - 0.0016 18.9 0.0 0.0056 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GBG88046.1 - 0.0028 17.9 0.0 0.0085 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GBG88046.1 - 0.19 11.9 0.0 0.66 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain RT_RNaseH_2 PF17919.1 GBG88048.1 - 1.2e-26 92.7 0.0 5.5e-26 90.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88048.1 - 2.5e-26 92.6 0.0 4.4e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88048.1 - 4.9e-23 81.4 0.0 2.1e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88048.1 - 4.2e-16 58.8 0.7 1.1e-15 57.4 0.7 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG88048.1 - 4.2e-06 27.3 0.0 9.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88048.1 - 6.4e-06 26.0 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88048.1 - 1.4e-05 25.6 0.0 3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG88048.1 - 0.00069 19.8 0.1 0.0034 17.6 0.1 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG88048.1 - 0.003 17.4 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease UPF0242 PF06785.11 GBG88049.1 - 1.7 8.7 9.2 0.26 11.4 5.4 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Imm27 PF15590.6 GBG88049.1 - 4.8 7.0 5.9 11 5.8 0.1 2.8 2 1 0 2 2 2 0 Immunity protein 27 RVT_1 PF00078.27 GBG88050.1 - 4.9e-28 98.2 0.1 7.9e-28 97.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG88050.1 - 2.7e-07 31.1 0.0 6.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88050.1 - 8.5e-07 29.4 0.0 2.4e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88050.1 - 4.1e-06 26.6 0.0 8.8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88050.1 - 0.00066 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG88050.1 - 0.056 13.7 0.1 0.056 13.7 0.1 3.9 3 1 0 3 3 3 0 Retrotransposon gag protein Syntaxin-6_N PF09177.11 GBG88050.1 - 0.58 10.7 4.0 2.6 8.7 0.5 2.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Integrase_H2C2 PF17921.1 GBG88051.1 - 2.9e-19 68.9 0.2 5.7e-19 68.0 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG88051.1 - 1.7e-15 57.1 0.1 4.1e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88051.1 - 1.8e-08 34.3 0.2 9.4e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88051.1 - 6.5e-06 26.3 0.1 3e-05 24.2 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain gag-asp_proteas PF13975.6 GBG88051.1 - 0.0033 18.0 0.0 0.0078 16.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG88051.1 - 0.0054 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG88051.1 - 0.01 16.4 0.0 0.034 14.8 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease Asp_protease PF09668.10 GBG88051.1 - 0.031 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG88052.1 - 0.00057 19.8 0.0 0.00088 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG88055.1 - 6e-05 23.1 0.0 6e-05 23.1 0.0 2.1 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG88055.1 - 0.00021 21.2 0.1 0.00044 20.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG88055.1 - 0.0026 17.9 0.1 0.0053 16.9 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG88055.1 - 0.0046 17.1 0.0 0.033 14.4 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain LRR_8 PF13855.6 GBG88058.1 - 2.4e-67 222.6 104.8 1e-05 25.2 0.2 23.2 11 5 11 25 25 25 19 Leucine rich repeat LRR_4 PF12799.7 GBG88058.1 - 5.2e-43 144.3 117.0 0.0048 17.3 0.1 27.5 13 5 15 33 33 33 21 Leucine Rich repeats (2 copies) NB-ARC PF00931.22 GBG88058.1 - 6.4e-31 107.4 0.0 1.4e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 GBG88058.1 - 6.5e-05 22.9 0.1 0.00019 21.4 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GBG88058.1 - 0.00067 20.1 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATP-synt_ab PF00006.25 GBG88058.1 - 0.0049 16.5 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 GBG88058.1 - 0.006 16.9 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GBG88058.1 - 0.17 12.3 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Asp_protease_2 PF13650.6 GBG88059.1 - 0.0001 22.8 0.0 0.00022 21.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88059.1 - 0.00011 22.7 0.0 0.00024 21.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88059.1 - 0.00055 19.7 0.0 0.00087 19.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88059.1 - 0.0076 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Lin-8 PF03353.15 GBG88059.1 - 0.28 10.7 3.2 0.43 10.1 3.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spore_coat_CotO PF14153.6 GBG88059.1 - 1.9 8.4 9.6 2.5 8.0 8.0 1.9 2 0 0 2 2 2 0 Spore coat protein CotO Cyclin PF08613.11 GBG88060.1 - 1.8e-36 125.9 0.3 3.7e-36 124.9 0.3 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GBG88060.1 - 5e-11 42.5 0.0 9e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Fungus-induced PF10917.8 GBG88060.1 - 0.22 11.9 2.2 4.7 7.6 0.2 2.8 2 0 0 2 2 2 0 Fungus-induced protein Methyltransf_16 PF10294.9 GBG88061.1 - 3.8e-07 30.0 0.1 0.002 17.9 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase MSP1_C PF07462.11 GBG88061.1 - 0.57 8.8 2.6 0.77 8.4 2.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Myb_DNA-bind_4 PF13837.6 GBG88062.1 - 6.5e-08 32.8 0.4 8.1e-07 29.3 0.3 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG88062.1 - 0.005 16.9 0.2 0.015 15.4 0.2 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG88063.1 - 6.4e-29 99.9 0.0 1.1e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88063.1 - 4e-27 94.6 0.0 6.7e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88063.1 - 3.2e-12 46.4 0.1 5e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG88063.1 - 0.0024 17.7 0.0 0.019 14.8 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2249) OGG_N PF07934.12 GBG88063.1 - 0.053 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain Bromodomain PF00439.25 GBG88064.1 - 2.8e-19 68.9 0.2 5.4e-19 68.0 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 GBG88064.1 - 1.7e-10 41.1 0.0 3.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GBG88064.1 - 2.2e-09 37.4 0.1 4.1e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GBG88064.1 - 4.5e-05 23.8 0.4 8.3e-05 22.9 0.4 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-GRF PF06839.12 GBG88064.1 - 0.095 12.8 2.1 0.23 11.6 0.2 2.2 2 0 0 2 2 2 0 GRF zinc finger UPF0054 PF02130.17 GBG88064.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 Elong-fact-P_C PF09285.11 GBG88065.1 - 6.7e-28 96.2 0.4 1.5e-27 95.1 0.4 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 GBG88065.1 - 5e-26 90.5 0.0 1.1e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 GBG88065.1 - 1.6e-16 60.0 0.0 3e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain DUF659 PF04937.15 GBG88066.1 - 1.3e-18 67.3 0.0 2.4e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88066.1 - 0.00086 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SATase_N PF06426.14 GBG88069.1 - 1.6e-36 124.8 0.2 3.1e-36 123.9 0.2 1.5 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 GBG88069.1 - 3.9e-08 32.7 6.0 1.3e-05 24.7 0.5 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GBG88069.1 - 0.084 12.6 4.6 0.081 12.7 1.4 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase NAD_binding_10 PF13460.6 GBG88070.1 - 7.2e-18 65.1 0.5 4.3e-15 56.1 0.4 2.4 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 GBG88070.1 - 9e-13 48.3 0.2 1.5e-12 47.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family CIA30 PF08547.12 GBG88070.1 - 4.7e-11 42.9 0.0 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Epimerase PF01370.21 GBG88070.1 - 2.6e-08 33.6 0.1 5.1e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GBG88070.1 - 0.00038 19.6 0.1 0.00055 19.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GBG88070.1 - 0.00057 19.4 0.0 0.00081 18.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 GBG88070.1 - 0.002 18.4 0.2 0.0038 17.5 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 GBG88070.1 - 0.004 16.6 0.4 0.0072 15.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 GBG88070.1 - 0.026 13.7 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.17 GBG88070.1 - 0.051 12.7 0.1 0.17 10.9 0.0 1.8 1 1 1 2 2 2 0 RmlD substrate binding domain WD40 PF00400.32 GBG88071.1 - 6.6e-19 67.9 8.8 3.3e-05 24.5 0.2 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG88071.1 - 0.0044 17.3 0.1 1.4 9.3 0.0 3.0 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG88071.1 - 0.016 13.9 0.6 0.075 11.7 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF659 PF04937.15 GBG88072.1 - 5.2e-25 88.1 0.0 9.3e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88072.1 - 3.6e-11 42.7 0.6 1.1e-10 41.2 0.6 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region WD40 PF00400.32 GBG88073.1 - 3.2e-18 65.7 1.8 5.8e-10 39.6 0.9 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 GBG88073.1 - 0.12 11.0 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like RVT_1 PF00078.27 GBG88074.1 - 5.4e-07 29.3 0.2 6.4e-07 29.1 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG88074.1 - 0.059 12.5 0.1 2.9 6.9 0.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg17 Ocnus PF05005.15 GBG88075.1 - 0.0011 19.0 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Coilin_N PF15862.5 GBG88075.1 - 0.0036 17.1 0.0 0.0036 17.1 0.0 7.5 1 1 6 7 7 7 1 Coilin N-terminus zf-NADH-PPase PF09297.11 GBG88075.1 - 0.0099 15.5 6.0 0.0099 15.5 6.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain RT_RNaseH_2 PF17919.1 GBG88076.1 - 1.3e-20 73.3 0.0 2.8e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88076.1 - 1.2e-17 64.1 0.0 3.1e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG88076.1 - 0.43 8.7 9.6 0.67 8.1 9.6 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG88076.1 - 2 7.7 17.5 4.5 6.5 11.0 2.2 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 GBG88076.1 - 2.3 6.4 8.7 3.6 5.8 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 GBG88076.1 - 3.5 7.4 6.8 9.1 6.0 6.8 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.12 GBG88076.1 - 4 6.8 15.1 0.091 12.2 8.5 1.6 2 0 0 2 2 2 0 SDA1 PPP4R2 PF09184.11 GBG88076.1 - 5.8 6.4 11.2 0.38 10.3 6.3 1.5 2 0 0 2 2 2 0 PPP4R2 Myb_DNA-bind_4 PF13837.6 GBG88077.1 - 0.0033 17.8 1.5 0.0072 16.7 1.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain AA_kinase PF00696.28 GBG88078.1 - 6.6e-28 97.9 0.0 4.8e-27 95.1 0.1 2.2 2 0 0 2 2 2 1 Amino acid kinase family RRM_1 PF00076.22 GBG88078.1 - 2e-12 46.7 0.0 4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG88078.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 GBG88078.1 - 0.033 14.0 0.0 0.16 11.8 0.0 2.0 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GBG88078.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Macoilin PF09726.9 GBG88078.1 - 1.3 7.5 6.1 2 6.8 6.1 1.3 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 GBG88078.1 - 3.8 6.2 6.1 6.4 5.5 6.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain LRRFIP PF09738.9 GBG88078.1 - 6.9 6.0 7.7 34 3.8 0.1 2.2 2 0 0 2 2 2 0 LRRFIP family TraG-D_C PF12696.7 GBG88079.1 - 0.011 15.8 0.3 0.029 14.4 0.3 1.7 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF4820 PF16091.5 GBG88079.1 - 0.022 14.1 0.3 0.022 14.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Nop25 PF09805.9 GBG88079.1 - 0.15 12.5 27.3 0.21 12.1 16.2 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Presenilin PF01080.17 GBG88079.1 - 0.63 8.7 12.2 3.2 6.4 7.5 2.1 2 0 0 2 2 2 0 Presenilin DUF3801 PF12687.7 GBG88079.1 - 1.2 9.1 12.1 0.27 11.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Mpp10 PF04006.12 GBG88079.1 - 2.1 6.7 34.6 0.063 11.7 21.1 2.1 2 0 0 2 2 2 0 Mpp10 protein SDA1 PF05285.12 GBG88079.1 - 3.9 6.8 39.1 0.21 11.0 23.5 2.1 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 GBG88079.1 - 7.6 5.8 32.4 0.46 9.8 19.4 2.3 2 0 0 2 2 2 0 BUD22 Ribonuclease_T2 PF00445.18 GBG88080.1 - 3.1e-31 109.0 0.2 1.4e-18 67.8 0.0 2.0 2 0 0 2 2 2 2 Ribonuclease T2 family Ribonuclease_T2 PF00445.18 GBG88081.1 - 8e-28 97.9 0.1 1.9e-16 60.9 0.0 2.3 2 1 0 2 2 2 2 Ribonuclease T2 family RVT_1 PF00078.27 GBG88081.1 - 0.0019 17.8 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SUR7 PF06687.12 GBG88081.1 - 0.033 13.8 3.3 0.056 13.1 3.3 1.3 1 0 0 1 1 1 0 SUR7/PalI family CTP_transf_1 PF01148.20 GBG88082.1 - 2.1e-60 204.7 14.1 2.6e-60 204.4 14.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Prominin PF05478.11 GBG88084.1 - 0.033 12.2 1.3 0.064 11.2 1.3 1.4 1 0 0 1 1 1 0 Prominin CCDC92 PF14916.6 GBG88084.1 - 0.4 10.5 12.4 1.4 8.7 0.1 4.4 4 1 0 4 4 4 0 Coiled-coil domain of unknown function NB-ARC PF00931.22 GBG88086.1 - 2.7e-34 118.5 0.0 1.8e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain LRR_8 PF13855.6 GBG88086.1 - 6.9e-20 70.6 22.3 4.3e-05 23.2 0.1 7.4 5 2 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 GBG88086.1 - 3.2e-14 52.8 15.3 0.23 11.9 0.1 9.4 6 3 5 11 11 11 5 Leucine Rich repeats (2 copies) NACHT PF05729.12 GBG88086.1 - 0.00061 19.7 1.7 0.031 14.2 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 GBG88086.1 - 0.0013 19.0 0.0 0.0041 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 GBG88086.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GBG88086.1 - 0.027 14.9 4.1 0.61 10.4 4.1 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 GBG88086.1 - 0.038 14.0 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain RT_RNaseH PF17917.1 GBG88087.1 - 1.9e-18 66.7 0.6 5.8e-18 65.1 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase AAA_23 PF13476.6 GBG88087.1 - 1.7e-13 51.5 0.3 1.7e-13 51.5 0.3 4.2 2 2 1 3 3 3 1 AAA domain Integrase_H2C2 PF17921.1 GBG88087.1 - 4e-12 46.1 1.9 1.5e-10 41.0 0.1 3.6 2 1 0 3 3 3 1 Integrase zinc binding domain SMC_N PF02463.19 GBG88087.1 - 4.8e-10 39.2 0.0 5.3e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RT_RNaseH_2 PF17919.1 GBG88087.1 - 2.5e-09 37.1 0.1 9.8e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase SbcCD_C PF13558.6 GBG88087.1 - 4.2e-06 26.9 0.0 1.7e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 GBG88087.1 - 0.00094 19.7 3.8 0.54 10.8 0.0 4.9 4 2 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 GBG88087.1 - 0.011 15.5 0.1 0.16 11.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system IncFII_repA PF02387.15 GBG88087.1 - 0.68 9.1 6.2 1.5 8.0 6.2 1.5 1 0 0 1 1 1 0 IncFII RepA protein family RVT_1 PF00078.27 GBG88088.1 - 5.4e-34 117.6 0.0 8.7e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88088.1 - 5.9e-17 61.5 0.0 1.3e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88088.1 - 6.6e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88089.1 - 3.9e-15 56.1 0.0 8.8e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF659 PF04937.15 GBG88090.1 - 6.2e-11 42.4 0.0 1.3e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88090.1 - 2.8e-09 36.6 0.0 6e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Drc1-Sld2 PF11719.8 GBG88091.1 - 0.022 14.3 12.1 0.026 14.1 12.1 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 GBG88091.1 - 0.21 9.7 17.8 0.2 9.8 17.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG88091.1 - 0.87 9.0 14.4 0.96 8.8 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PI3K_1B_p101 PF10486.9 GBG88091.1 - 1.3 6.7 8.8 1.4 6.6 8.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 GBG88091.1 - 3 6.0 25.6 3.3 5.9 25.6 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG88091.1 - 3.2 7.1 23.9 3.6 6.9 23.9 1.1 1 0 0 1 1 1 0 SDA1 FYDLN_acid PF09538.10 GBG88091.1 - 3.6 8.3 18.6 6.3 7.5 18.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Mem_trans PF03547.18 GBG88091.1 - 5.8 5.2 5.9 6.3 5.1 5.9 1.0 1 0 0 1 1 1 0 Membrane transport protein Merozoite_SPAM PF07133.11 GBG88091.1 - 5.9 6.8 31.2 8 6.4 31.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF4637 PF15470.6 GBG88091.1 - 7.4 6.3 18.2 9.8 5.9 18.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DDE_Tnp_4 PF13359.6 GBG88093.1 - 3.6e-27 95.0 0.0 5e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88093.1 - 1.7e-12 47.3 0.0 2.4e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88093.1 - 6.6e-05 22.6 0.1 0.00097 18.8 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG88093.1 - 0.045 14.1 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Pro-MCH PF05824.12 GBG88093.1 - 0.081 12.9 0.1 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) RRM_1 PF00076.22 GBG88094.1 - 3.9e-16 58.6 0.0 6.5e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 GBG88094.1 - 0.047 13.7 12.6 0.19 11.7 0.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 GBG88095.1 - 5.1e-10 39.8 0.3 1.3e-09 38.5 0.3 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FAM76 PF16046.5 GBG88098.1 - 0.019 14.4 5.4 0.021 14.2 5.4 1.1 1 0 0 1 1 1 0 FAM76 protein DUF3573 PF12097.8 GBG88098.1 - 0.58 8.9 1.7 0.67 8.7 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) RVT_1 PF00078.27 GBG88099.1 - 2.9e-25 89.1 0.0 4.7e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88099.1 - 7.8e-24 84.0 0.0 1.6e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88099.1 - 7.4e-23 80.5 0.0 2.1e-11 43.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88099.1 - 8.3e-14 51.4 2.0 2.4e-13 50.0 0.0 2.9 4 0 0 4 4 4 1 Integrase zinc binding domain Chromo PF00385.24 GBG88099.1 - 7.9e-12 44.9 0.0 1.8e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG88099.1 - 1.3e-09 38.3 0.1 6.1e-09 36.1 0.1 2.2 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG88099.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger SPC25 PF06703.11 GBG88100.1 - 1.7 8.4 5.1 2 8.2 5.1 1.1 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CDC27 PF09507.10 GBG88100.1 - 6.7 6.0 22.3 7.9 5.7 22.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PIG-S PF10510.9 GBG88101.1 - 2e-94 317.3 0.0 1.4e-85 288.1 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein NOA36 PF06524.12 GBG88101.1 - 4.5 6.5 9.2 9.9 5.4 9.2 1.5 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 GBG88102.1 - 2.1 7.0 2.9 2.5 6.8 2.9 1.1 1 0 0 1 1 1 0 Presenilin Arm PF00514.23 GBG88105.1 - 8.4e-43 143.2 10.9 8e-08 32.1 0.0 10.9 10 1 0 10 10 10 8 Armadillo/beta-catenin-like repeat BTB PF00651.31 GBG88105.1 - 5.3e-28 97.5 0.2 2.8e-26 91.9 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain HEAT_2 PF13646.6 GBG88105.1 - 4.6e-10 39.8 14.9 0.0057 17.0 0.2 6.5 3 1 5 8 8 8 4 HEAT repeats HEAT PF02985.22 GBG88105.1 - 2.7e-09 36.5 7.5 0.058 13.7 0.1 7.5 7 0 0 7 7 7 1 HEAT repeat V-ATPase_H_N PF03224.14 GBG88105.1 - 7.2e-07 28.8 0.0 0.024 13.9 0.0 3.8 1 1 2 3 3 3 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 GBG88105.1 - 1.6e-06 28.0 0.1 0.00064 19.7 0.0 3.1 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 GBG88105.1 - 4.9e-06 26.9 13.8 0.018 15.6 0.4 6.6 6 1 1 7 7 7 3 HEAT-like repeat Adaptin_N PF01602.20 GBG88105.1 - 0.00038 19.1 0.0 0.065 11.8 0.0 3.4 1 1 3 4 4 4 1 Adaptin N terminal region DUF5578 PF17741.1 GBG88105.1 - 0.0022 17.5 0.4 3 7.2 0.0 3.6 2 2 2 4 4 4 1 Family of unknown function (DUF5578) Cnd1 PF12717.7 GBG88105.1 - 0.005 16.9 0.0 2.7 8.0 0.0 3.2 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 GBG88105.1 - 0.014 15.4 0.1 6.7 6.6 0.0 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF3361) RICTOR_N PF14664.6 GBG88105.1 - 0.045 12.8 0.0 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Thioredoxin_12 PF18400.1 GBG88105.1 - 0.054 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Aconitase_B_N PF11791.8 GBG88105.1 - 0.23 11.5 2.8 25 4.9 0.0 4.1 4 1 0 4 4 4 0 Aconitate B N-terminal domain NopRA1 PF16201.5 GBG88105.1 - 0.28 10.8 0.9 6 6.4 0.0 3.2 3 1 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Integrase_H2C2 PF17921.1 GBG88107.1 - 2.3e-07 30.8 0.1 3.9e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88107.1 - 0.0029 17.8 0.0 0.0077 16.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG88108.1 - 9.7e-12 45.1 0.0 1.7e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88108.1 - 0.0041 17.1 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Lin-8 PF03353.15 GBG88108.1 - 0.49 9.9 3.1 0.7 9.4 3.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 GBG88108.1 - 2.2 6.4 6.9 2.7 6.1 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG88108.1 - 2.3 6.4 5.1 3.1 6.0 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein CDC45 PF02724.14 GBG88110.1 - 0.17 10.2 9.2 0.17 10.1 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG88110.1 - 0.48 9.8 11.5 0.48 9.8 11.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG88110.1 - 0.82 7.8 12.4 0.87 7.7 12.4 1.0 1 0 0 1 1 1 0 Nop14-like family Exonuc_VII_L PF02601.15 GBG88111.1 - 0.028 14.0 7.6 0.039 13.5 7.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit mTERF PF02536.14 GBG88111.1 - 0.043 12.7 1.8 0.074 12.0 1.8 1.4 1 0 0 1 1 1 0 mTERF Med4 PF10018.9 GBG88111.1 - 0.045 13.4 10.8 0.014 15.0 5.8 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Het-C PF07217.11 GBG88111.1 - 0.086 11.4 3.5 0.12 10.8 3.5 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C UPF0242 PF06785.11 GBG88111.1 - 0.32 11.1 18.1 0.32 11.1 17.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LRS4 PF10422.9 GBG88111.1 - 1.8 8.1 14.0 2.8 7.5 0.4 2.2 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 DUF4404 PF14357.6 GBG88111.1 - 2.3 8.9 10.4 4.7 7.9 9.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) APC_N_CC PF16689.5 GBG88113.1 - 0.0083 16.2 4.0 0.03 14.4 0.5 3.2 3 1 0 3 3 3 1 Coiled-coil N-terminus of APC, dimerisation domain Atg14 PF10186.9 GBG88113.1 - 1 8.4 11.0 1.9 7.5 11.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 GBG88113.1 - 2.7 7.8 12.9 0.56 10.0 1.8 3.1 1 1 1 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 GBG88113.1 - 8.8 6.8 10.3 0.21 12.0 1.3 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RT_RNaseH PF17917.1 GBG88114.1 - 5.2e-18 65.3 0.0 8e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88114.1 - 1.6e-09 37.7 0.0 2.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG88114.1 - 7 4.8 11.9 8.8 4.5 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG88114.1 - 9.6 4.3 17.0 13 3.9 17.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1997 PF09366.10 GBG88116.1 - 1.5e-17 64.2 0.0 1.9e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) DUF3390 PF11870.8 GBG88117.1 - 9.1e-19 67.6 0.6 8.5 6.8 0.0 8.6 8 0 0 8 8 8 8 Domain of unknown function (DUF3390) HHV-5_US34A PF17087.5 GBG88117.1 - 1.1e-14 54.2 43.6 1.6 9.0 0.3 9.7 9 0 0 9 9 9 9 Herpesvirus US34A protein family Dis3l2_C_term PF17877.1 GBG88117.1 - 4.4e-05 23.7 18.8 1e+02 3.3 0.0 9.1 9 0 0 9 9 9 0 DIS3-like exonuclease 2 C terminal GH-E PF14410.6 GBG88117.1 - 0.00014 22.2 16.7 1.5e+02 2.8 0.0 9.5 9 0 0 9 9 9 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Integrase_H2C2 PF17921.1 GBG88118.1 - 7e-18 64.5 0.0 1.5e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88118.1 - 3.1e-09 37.0 0.0 1e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG88118.1 - 6.9e-08 32.4 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG88118.1 - 4.3e-07 29.7 0.1 9.2e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG88118.1 - 4.8e-07 30.3 0.0 1.1e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88118.1 - 5.5e-05 23.6 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88118.1 - 0.0051 16.6 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG88118.1 - 0.02 15.1 0.0 0.05 13.8 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger SlyX PF04102.12 GBG88118.1 - 0.043 14.4 0.4 0.043 14.4 0.4 3.3 3 0 0 3 3 3 0 SlyX RT_RNaseH PF17917.1 GBG88118.1 - 0.092 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF16 PF01519.16 GBG88118.1 - 0.27 11.7 0.9 0.64 10.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 DDE_Tnp_4 PF13359.6 GBG88119.1 - 8.6e-27 93.7 0.0 2.2e-26 92.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88119.1 - 2.3e-15 56.8 0.0 3.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88119.1 - 0.0027 17.4 0.4 0.036 13.7 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain RVT_1 PF00078.27 GBG88122.1 - 2e-24 86.3 0.0 3.2e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88122.1 - 0.00017 21.6 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BUD22 PF09073.10 GBG88122.1 - 2.7 7.2 22.1 3.8 6.7 22.1 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG88122.1 - 9.3 4.3 20.0 12 3.9 20.0 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG88125.1 - 1.5e-36 126.0 0.0 2.3e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box-like PF12937.7 GBG88126.1 - 2.1e-08 33.9 0.2 5.3e-08 32.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG88126.1 - 7.6e-07 28.9 0.4 2.8e-06 27.1 0.4 2.1 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 GBG88126.1 - 0.0035 17.7 0.3 2.2 8.8 0.0 4.6 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 GBG88126.1 - 1.5 9.6 12.0 11 6.8 0.1 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat Oxysterol_BP PF01237.18 GBG88127.1 - 1 8.1 7.7 1.2 7.9 7.7 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Presenilin PF01080.17 GBG88127.1 - 3.9 6.1 7.0 4.7 5.9 7.0 1.1 1 0 0 1 1 1 0 Presenilin Iron_permease PF04120.12 GBG88127.1 - 4.2 7.2 5.7 6.6 6.5 5.7 1.2 1 0 0 1 1 1 0 Low affinity iron permease zf-CCHC PF00098.23 GBG88128.1 - 3.3e-07 30.1 1.9 6.7e-07 29.1 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG88128.1 - 0.0043 16.7 1.0 0.0089 15.7 1.0 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG88128.1 - 0.05 13.3 0.8 0.1 12.4 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF5383 PF17355.2 GBG88128.1 - 5.7 7.3 12.9 18 5.7 12.9 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Pox_G5 PF04599.12 GBG88128.1 - 6.9 5.6 8.2 15 4.4 8.2 1.5 1 0 0 1 1 1 0 Poxvirus G5 protein MT-A70 PF05063.14 GBG88129.1 - 4.9e-17 62.4 0.0 6.3e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 MT-A70 RVT_1 PF00078.27 GBG88130.1 - 1.4e-33 116.3 0.1 2.4e-33 115.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG88130.1 - 1.1e-17 64.3 0.6 4.3e-08 33.2 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88130.1 - 0.00053 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SesA PF17107.5 GBG88130.1 - 0.023 14.9 0.3 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DSHCT PF08148.12 GBG88130.1 - 0.12 12.0 4.2 0.22 11.2 0.2 2.8 3 0 0 3 3 3 0 DSHCT (NUC185) domain DUF3450 PF11932.8 GBG88130.1 - 0.34 10.2 2.1 0.3 10.4 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) RVT_1 PF00078.27 GBG88131.1 - 6.2e-54 182.8 0.5 1.2e-31 110.0 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88131.1 - 2e-43 146.5 0.0 7.1e-26 90.2 0.0 3.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88131.1 - 1.7e-24 86.1 0.2 2.8e-15 56.5 0.0 3.4 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase MT-A70 PF05063.14 GBG88131.1 - 0.031 14.2 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 MT-A70 DUF659 PF04937.15 GBG88132.1 - 6e-31 107.4 0.0 1e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Ribosomal_60s PF00428.19 GBG88132.1 - 0.0015 19.1 19.9 0.096 13.3 6.9 2.7 2 0 0 2 2 2 2 60s Acidic ribosomal protein RT_RNaseH_2 PF17919.1 GBG88133.1 - 3.3e-30 104.1 0.0 8.8e-30 102.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88133.1 - 1.1e-29 102.8 0.0 2.4e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88133.1 - 1.2e-14 54.4 0.1 2.3e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88133.1 - 1.8e-10 40.8 0.0 4.4e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88133.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG88133.1 - 0.9 9.1 3.5 0.8 9.3 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase MT-A70 PF05063.14 GBG88134.1 - 0.019 14.9 0.2 0.025 14.5 0.2 1.2 1 0 0 1 1 1 0 MT-A70 VID27 PF08553.10 GBG88135.1 - 1.3e-46 159.3 0.0 2e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain WD40 PF00400.32 GBG88135.1 - 0.017 16.0 0.1 11 7.1 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Nop14 PF04147.12 GBG88135.1 - 2.4 6.2 9.5 3.3 5.8 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG88135.1 - 2.5 6.1 10.5 3.5 5.6 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 GBG88135.1 - 4.4 7.0 6.5 9.2 5.9 6.5 1.5 1 0 0 1 1 1 0 FAM176 family DUF2514 PF10721.9 GBG88135.1 - 8.8 6.3 10.1 14 5.6 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RVT_1 PF00078.27 GBG88137.1 - 1e-05 25.2 1.0 0.023 14.2 0.1 2.5 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88138.1 - 1.3e-16 60.5 0.5 5.3e-16 58.5 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG88138.1 - 1.3e-12 48.0 0.0 3.3e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG88138.1 - 3.2e-12 46.2 0.0 6.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG88138.1 - 9.4e-05 22.5 0.0 0.00027 21.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG88139.1 - 2e-16 60.2 0.1 3e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG88139.1 - 8e-10 38.5 0.1 1.5e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.14 GBG88141.1 - 6.3e-05 22.7 0.9 0.00013 21.7 0.9 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region IGF2_C PF08365.11 GBG88141.1 - 1.1 9.4 4.0 6.7 6.8 0.6 2.6 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide Peptidase_C48 PF02902.19 GBG88143.1 - 2e-19 70.3 0.0 4.6e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF659 PF04937.15 GBG88145.1 - 9.1e-18 64.6 0.0 2.3e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88145.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 GBG88145.1 - 0.0036 17.3 0.2 0.007 16.4 0.2 1.5 1 0 0 1 1 1 1 BED zinc finger DUF2974 PF11187.8 GBG88145.1 - 0.094 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PyrI_C PF02748.15 GBG88145.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Integrase_H2C2 PF17921.1 GBG88146.1 - 1.6e-08 34.5 0.1 4.9e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG88146.1 - 1.1e-06 29.1 0.1 3.1e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88146.1 - 1.3e-05 25.8 0.1 3.8e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG88146.1 - 0.013 15.3 0.8 0.025 14.4 0.8 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG88146.1 - 0.034 14.4 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein PGA2 PF07543.12 GBG88146.1 - 4.3 7.3 14.5 1.5 8.8 8.5 2.6 2 0 0 2 2 2 0 Protein trafficking PGA2 PTPRCAP PF15713.5 GBG88146.1 - 6.6 7.0 12.6 0.058 13.7 3.9 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF659 PF04937.15 GBG88148.1 - 3.8e-33 114.5 0.0 5.6e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG88150.1 - 1e-08 35.4 0.5 2e-08 34.5 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG88150.1 - 0.15 12.4 0.3 0.25 11.7 0.3 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG88151.1 - 1.7e-32 112.3 0.0 3e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88151.1 - 2.4e-13 50.1 0.0 3.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88151.1 - 0.0023 17.6 0.0 1.8 8.2 0.1 2.5 2 0 0 2 2 2 2 Transposase DDE domain RVT_1 PF00078.27 GBG88152.1 - 1.3e-29 103.3 0.0 2.1e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88152.1 - 2.2e-28 98.2 0.0 7e-14 51.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88152.1 - 7.3e-27 93.7 0.0 1.5e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88152.1 - 1.7e-11 44.3 0.1 1.5e-10 41.3 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG88152.1 - 1.6e-10 41.0 0.0 6.8e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88152.1 - 0.036 14.3 0.0 0.099 12.9 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger UDPG_MGDP_dh_N PF03721.14 GBG88154.1 - 4e-64 215.6 0.1 6e-64 215.1 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 GBG88154.1 - 4.5e-34 117.0 0.0 2.9e-33 114.4 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 GBG88154.1 - 1.4e-30 105.4 0.1 3.7e-30 104.0 0.1 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 GBG88154.1 - 0.00056 20.1 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 GBG88154.1 - 0.097 12.9 0.0 0.64 10.3 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Myb_DNA-bind_4 PF13837.6 GBG88155.1 - 5.3e-06 26.7 0.9 9.9e-06 25.9 0.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG88155.1 - 0.0012 18.9 0.5 0.002 18.2 0.5 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CENP-B_dimeris PF09026.10 GBG88155.1 - 0.21 12.0 5.0 0.63 10.5 5.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF726 PF05277.12 GBG88156.1 - 2.1e-72 244.0 3.1 2.3e-42 145.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF726) Myb_DNA-bind_4 PF13837.6 GBG88158.1 - 0.00018 21.9 0.5 0.0003 21.1 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG88158.1 - 0.059 13.5 0.3 0.097 12.8 0.3 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain JMY PF15871.5 GBG88158.1 - 0.14 11.4 0.2 0.21 10.9 0.2 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein TetR_C_24 PF17932.1 GBG88158.1 - 0.18 12.1 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Myb_DNA-bind_4 PF13837.6 GBG88159.1 - 0.0001 22.6 0.5 0.00017 21.9 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG88159.1 - 0.033 14.3 0.3 0.056 13.5 0.3 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain JMY PF15871.5 GBG88159.1 - 0.081 12.2 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein TetR_C_24 PF17932.1 GBG88159.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SRP-alpha_N PF04086.13 GBG88160.1 - 0.062 13.2 9.2 0.054 13.4 7.5 1.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Cyt-b5 PF00173.28 GBG88160.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Big_1 PF02369.16 GBG88161.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) RVT_1 PF00078.27 GBG88162.1 - 1.1e-28 100.3 0.1 1.4e-28 99.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88162.1 - 2.3e-13 50.0 0.0 5.4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88162.1 - 2e-07 31.3 0.0 4.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG88163.1 - 0.36 11.1 0.1 0.36 11.1 0.1 3.6 3 2 0 4 4 4 0 Retrotransposon gag protein PIEZO PF15917.5 GBG88163.1 - 1.8 8.0 7.7 1.8 8.0 5.3 1.9 2 0 0 2 2 2 0 Piezo Ank_2 PF12796.7 GBG88164.1 - 5.4e-18 65.4 0.0 1.7e-07 31.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG88164.1 - 2.1e-17 63.2 0.0 2e-08 34.6 0.0 3.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG88164.1 - 9.7e-16 57.6 0.1 2.7e-07 30.7 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG88164.1 - 1.6e-14 52.5 0.3 8.4e-05 22.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 GBG88164.1 - 5.7e-13 48.7 1.7 8.8e-05 22.8 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Synaptobrevin PF00957.21 GBG88165.1 - 0.0014 18.4 3.6 0.0014 18.4 3.6 1.8 1 1 1 2 2 2 1 Synaptobrevin DUF3404 PF11884.8 GBG88165.1 - 0.0039 16.5 0.5 0.0039 16.5 0.5 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3404) SNARE PF05739.19 GBG88165.1 - 0.02 14.9 6.2 0.02 14.9 6.2 1.9 2 0 0 2 2 2 0 SNARE domain Orf78 PF06024.12 GBG88165.1 - 0.039 14.2 0.1 0.055 13.8 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF2628 PF10947.8 GBG88165.1 - 0.16 12.4 3.3 0.21 12.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) RIFIN PF02009.16 GBG88165.1 - 0.16 11.8 2.1 0.2 11.5 2.1 1.1 1 0 0 1 1 1 0 Rifin DUF2207 PF09972.9 GBG88165.1 - 0.17 10.6 0.6 0.17 10.6 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tmemb_9 PF05434.11 GBG88165.1 - 0.22 11.4 4.6 0.38 10.7 4.6 1.4 1 1 0 1 1 1 0 TMEM9 S_4TM PF18159.1 GBG88165.1 - 0.54 9.5 2.9 0.63 9.3 2.9 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Ferlin_C PF16165.5 GBG88165.1 - 0.56 10.2 1.8 0.54 10.2 1.3 1.3 1 1 0 1 1 1 0 Ferlin C-terminus SP_C-Propep PF08999.10 GBG88165.1 - 0.74 9.6 6.8 1.3 8.8 6.9 1.4 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide IQCJ-SCHIP1 PF15157.6 GBG88165.1 - 1.6 8.5 5.5 1.9 8.3 5.5 1.1 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF5534 PF17686.1 GBG88165.1 - 2 8.7 4.3 2.4 8.4 4.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5534) TMEM154 PF15102.6 GBG88165.1 - 2.1 8.3 7.9 3.1 7.7 7.9 1.3 1 1 0 1 1 1 0 TMEM154 protein family ETRAMP PF09716.10 GBG88165.1 - 3.2 7.9 5.0 5 7.3 4.6 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) OppC_N PF12911.7 GBG88165.1 - 6.1 6.9 11.3 65 3.6 11.3 2.1 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C GRDP-like PF07173.12 GBG88167.1 - 4.8 7.8 7.4 0.66 10.6 0.7 2.8 3 0 0 3 3 3 0 Glycine-rich domain-containing protein-like Toxin_4 PF00706.17 GBG88168.1 - 0.063 13.7 0.5 0.12 12.9 0.5 1.4 1 0 0 1 1 1 0 Anenome neurotoxin Na_trans_assoc PF06512.13 GBG88168.1 - 0.1 12.9 36.5 0.81 9.9 17.5 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated SAPS PF04499.15 GBG88168.1 - 0.25 10.1 16.1 0.054 12.3 4.3 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 GBG88168.1 - 1.4 8.7 18.5 1.1 9.0 3.6 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein SDA1 PF05285.12 GBG88168.1 - 4.4 6.6 52.2 4.3 6.7 18.9 2.1 2 0 0 2 2 2 0 SDA1 BORG_CEP PF14957.6 GBG88168.1 - 4.9 8.3 13.2 6.6 7.9 0.6 2.3 2 0 0 2 2 2 0 Cdc42 effector Cupin_6 PF12852.7 GBG88169.1 - 0.063 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Cupin 14-3-3 PF00244.20 GBG88170.1 - 1.1e-102 342.3 5.0 1.2e-102 342.1 5.0 1.0 1 0 0 1 1 1 1 14-3-3 protein P4Ha_N PF08336.11 GBG88170.1 - 0.01 15.8 1.2 0.026 14.5 1.2 1.6 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TPR_19 PF14559.6 GBG88170.1 - 0.67 10.5 4.1 5.4 7.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat XhlA PF10779.9 GBG88170.1 - 6.3 7.1 6.9 5.5 7.3 0.5 2.4 2 0 0 2 2 2 0 Haemolysin XhlA RT_RNaseH_2 PF17919.1 GBG88171.1 - 4.4e-33 113.3 0.0 1e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88171.1 - 1.8e-29 102.1 0.1 7e-29 100.2 0.1 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88171.1 - 2.5e-16 59.5 0.0 6.9e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain IQ PF00612.27 GBG88171.1 - 3.3e-05 23.3 0.6 0.00011 21.6 0.6 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif rve PF00665.26 GBG88171.1 - 0.0047 17.1 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG88172.1 - 5.2e-09 36.6 0.0 1.6e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88172.1 - 8.5e-07 29.5 0.0 2.3e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88172.1 - 2.3e-05 24.2 0.0 3.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88172.1 - 0.031 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG88172.1 - 0.12 12.1 0.2 0.26 11.0 0.2 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVT_1 PF00078.27 GBG88173.1 - 1.4e-10 41.1 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTPRCAP PF15713.5 GBG88173.1 - 0.014 15.7 7.8 0.047 14.0 8.5 1.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated BSP_II PF05432.11 GBG88173.1 - 1.4 8.6 21.0 1.8 8.2 21.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Gln-synt_C PF00120.24 GBG88174.1 - 1.7e-15 56.9 0.0 1.7e-12 47.0 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG88174.1 - 2.9e-11 42.9 0.0 5.3e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PA26 PF04636.13 GBG88176.1 - 0.038 12.9 9.5 0.039 12.9 9.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Nop53 PF07767.11 GBG88176.1 - 0.097 12.1 19.4 0.1 11.9 19.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF1917 PF08939.10 GBG88176.1 - 0.12 12.2 8.9 0.15 11.9 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) DUF3629 PF12302.8 GBG88176.1 - 0.19 11.1 8.6 0.25 10.8 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DUF3138 PF11336.8 GBG88176.1 - 0.27 9.8 0.3 0.3 9.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TssO PF17561.2 GBG88176.1 - 0.88 9.7 6.8 1.2 9.2 6.8 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF5401 PF17380.2 GBG88176.1 - 3 5.8 20.4 3.2 5.7 20.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4407 PF14362.6 GBG88176.1 - 5 6.4 9.6 5.8 6.2 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1943 PF09172.11 GBG88176.1 - 5.2 6.2 6.6 6.5 5.9 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Presenilin PF01080.17 GBG88176.1 - 6.2 5.5 10.5 6.4 5.4 10.5 1.0 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 GBG88176.1 - 8.9 4.3 9.7 8.6 4.3 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Gln-synt_C PF00120.24 GBG88177.1 - 1.7e-15 56.9 0.0 1.7e-12 47.0 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG88177.1 - 3.4e-11 42.7 0.0 6.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RT_RNaseH_2 PF17919.1 GBG88178.1 - 1.5e-31 108.4 0.0 3.2e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88178.1 - 1.5e-27 95.9 0.1 2.8e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88178.1 - 2e-17 63.4 0.3 5.1e-17 62.1 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG88178.1 - 1.8e-13 50.7 0.0 4.1e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Glyoxalase PF00903.25 GBG88178.1 - 6.2e-05 23.2 0.0 0.00032 20.9 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GBG88178.1 - 0.00013 22.2 0.2 0.043 14.1 0.0 3.0 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 GBG88178.1 - 0.00094 19.4 0.3 0.0083 16.3 0.0 2.6 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 GBG88178.1 - 0.15 12.2 0.1 1.6 8.8 0.1 2.4 1 1 0 1 1 1 0 Glyoxalase-like domain DEAD PF00270.29 GBG88179.1 - 3e-38 131.4 0.0 6.3e-38 130.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG88179.1 - 6.3e-30 103.8 0.1 5.4e-28 97.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG88179.1 - 5.8e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GBG88179.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RT_RNaseH_2 PF17919.1 GBG88180.1 - 8e-30 102.8 0.0 1.4e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88180.1 - 6.4e-25 87.5 0.0 1.3e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase F-box-like PF12937.7 GBG88182.1 - 0.00038 20.3 0.0 0.0013 18.6 0.0 2.0 1 0 0 1 1 1 1 F-box-like NUC202 PF08166.12 GBG88182.1 - 0.087 12.9 0.8 0.26 11.4 0.5 2.0 1 1 0 1 1 1 0 NUC202 domain MR_MLE_C PF13378.6 GBG88182.1 - 0.11 12.0 0.0 0.47 10.0 0.0 2.2 1 1 0 1 1 1 0 Enolase C-terminal domain-like F-box PF00646.33 GBG88182.1 - 3.5 7.6 5.9 0.55 10.2 0.3 2.5 3 0 0 3 3 3 0 F-box domain Gp_dh_C PF02800.20 GBG88183.1 - 1.5e-69 232.6 0.0 2e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG88183.1 - 1.4e-38 131.3 0.0 2.8e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG88183.1 - 0.0035 17.5 0.4 0.012 15.7 0.0 2.1 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 GBG88183.1 - 0.081 12.8 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H-binding Radical_SAM PF04055.21 GBG88183.1 - 0.2 12.0 0.0 1.6 9.1 0.0 2.0 2 0 0 2 2 2 0 Radical SAM superfamily RVT_1 PF00078.27 GBG88184.1 - 2.2e-19 69.9 0.0 1.2e-18 67.5 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG88184.1 - 6e-08 33.2 0.0 1.5e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88184.1 - 3.5e-07 30.7 0.0 1.6e-06 28.6 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88184.1 - 8e-05 22.4 0.2 0.00024 20.9 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88184.1 - 0.00016 21.4 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG88184.1 - 0.0036 17.6 0.1 0.0036 17.6 0.1 4.3 4 1 0 4 4 4 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG88184.1 - 0.74 9.1 12.4 0.38 10.1 5.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Adaptin_binding PF10199.9 GBG88184.1 - 7.1 7.3 8.7 24 5.6 8.7 1.9 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Aminotran_4 PF01063.19 GBG88185.1 - 1.7e-21 77.1 0.0 2.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Actin PF00022.19 GBG88186.1 - 8.3e-122 406.7 0.0 1.2e-121 406.2 0.0 1.2 1 0 0 1 1 1 1 Actin Aminotran_4 PF01063.19 GBG88186.1 - 7.9e-18 65.1 0.0 1.9e-10 41.0 0.0 2.3 1 1 1 2 2 2 2 Amino-transferase class IV MreB_Mbl PF06723.13 GBG88186.1 - 5.8e-07 28.6 0.0 0.00022 20.2 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Ppx-GppA PF02541.16 GBG88186.1 - 0.046 13.2 0.1 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family FtsA PF14450.6 GBG88186.1 - 0.17 12.3 1.3 1.3 9.5 0.2 2.6 2 1 0 2 2 2 0 Cell division protein FtsA Actin PF00022.19 GBG88187.1 - 2.7e-144 480.8 0.0 3.9e-144 480.2 0.0 1.2 1 0 0 1 1 1 1 Actin Aminotran_4 PF01063.19 GBG88187.1 - 9.8e-18 64.8 0.0 2.1e-10 40.8 0.0 2.3 1 1 1 2 2 2 2 Amino-transferase class IV MreB_Mbl PF06723.13 GBG88187.1 - 7.3e-07 28.3 0.0 0.00024 20.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Ppx-GppA PF02541.16 GBG88187.1 - 0.052 13.0 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family FtsA PF14450.6 GBG88187.1 - 0.19 12.1 1.1 1.5 9.3 0.3 2.6 2 1 0 2 2 2 0 Cell division protein FtsA Snapin_Pallidin PF14712.6 GBG88189.1 - 0.00093 19.6 3.1 0.00093 19.6 3.1 2.1 1 1 1 2 2 2 1 Snapin/Pallidin Cytochrom_CIII PF02085.16 GBG88189.1 - 0.049 14.0 0.4 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 Class III cytochrome C family BRI3BP PF14965.6 GBG88189.1 - 0.11 12.1 1.3 0.26 10.8 1.3 1.6 1 0 0 1 1 1 0 Negative regulator of p53/TP53 TSC22 PF01166.18 GBG88189.1 - 1 9.7 8.7 0.093 13.0 2.5 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4407 PF14362.6 GBG88189.1 - 1.5 8.1 14.0 3.5 6.9 14.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RT_RNaseH_2 PF17919.1 GBG88190.1 - 8.8e-30 102.7 0.0 5.3e-14 52.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88190.1 - 4.4e-29 100.9 0.0 1.1e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88190.1 - 1.4e-26 93.4 0.0 2.8e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88190.1 - 3.7e-17 62.2 0.3 1e-16 60.7 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG88190.1 - 6.3e-12 45.2 0.0 1.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG88190.1 - 1.1e-09 38.4 0.3 4.5e-09 36.5 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG88190.1 - 0.0002 21.5 0.1 0.00046 20.3 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 GBG88190.1 - 0.22 11.4 0.0 0.46 10.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Trypsin PF00089.26 GBG88192.1 - 1.8e-05 24.6 0.1 2.8e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Trypsin BaxI_1 PF12811.7 GBG88192.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF3357 PF11837.8 GBG88192.1 - 0.28 11.7 1.5 23 5.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Trypsin PF00089.26 GBG88193.1 - 2.8e-32 112.3 0.4 5.2e-32 111.5 0.4 1.5 1 0 0 1 1 1 1 Trypsin Tup_N PF08581.10 GBG88194.1 - 0.08 13.2 7.8 8.3 6.8 0.4 4.1 3 1 0 3 3 3 0 Tup N-terminal SICA_alpha PF12887.7 GBG88194.1 - 0.11 12.4 2.2 0.25 11.2 2.2 1.5 1 0 0 1 1 1 0 SICA extracellular alpha domain DUF4407 PF14362.6 GBG88194.1 - 0.38 10.0 9.5 0.14 11.5 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4795 PF16043.5 GBG88194.1 - 0.63 9.6 11.3 1.5 8.4 5.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) LPP PF04728.13 GBG88194.1 - 0.65 10.4 7.1 16 6.0 3.9 3.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Prefoldin_2 PF01920.20 GBG88194.1 - 1.1 9.3 12.5 0.47 10.4 2.4 3.9 2 1 0 3 3 3 0 Prefoldin subunit PIN_9 PF18477.1 GBG88194.1 - 5.6 7.3 7.5 1.3 9.3 0.8 2.5 2 1 0 2 2 2 0 PIN like domain DUF3584 PF12128.8 GBG88194.1 - 6.9 4.0 17.7 0.13 9.8 10.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fzo_mitofusin PF04799.13 GBG88194.1 - 9.1 5.8 10.4 0.83 9.2 0.3 3.0 2 1 2 4 4 4 0 fzo-like conserved region DUF4140 PF13600.6 GBG88194.1 - 9.6 6.7 13.6 4.8e+02 1.3 0.1 4.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ras PF00071.22 GBG88196.1 - 9e-60 201.0 0.1 1e-59 200.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG88196.1 - 3.2e-34 117.7 0.0 6.4e-34 116.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG88196.1 - 7e-13 48.4 0.0 7.6e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GBG88196.1 - 8.7e-05 22.0 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GBG88196.1 - 0.00017 21.7 0.0 0.00031 20.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG88196.1 - 0.00025 21.0 0.2 0.69 9.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GBG88196.1 - 0.0006 19.4 0.0 0.005 16.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GBG88196.1 - 0.012 15.0 0.1 0.17 11.3 0.0 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit ATPase PF06745.13 GBG88196.1 - 0.027 13.8 0.1 3.2 7.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 GBG88196.1 - 0.037 14.4 0.1 0.071 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 GBG88196.1 - 0.048 13.7 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GBG88196.1 - 0.056 13.2 0.1 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain CobA_CobO_BtuR PF02572.15 GBG88196.1 - 0.072 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ABC_tran PF00005.27 GBG88196.1 - 0.18 12.3 0.1 0.22 12.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Metallophos PF00149.28 GBG88197.1 - 7.2e-37 127.9 0.1 8.9e-37 127.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GBG88197.1 - 0.019 15.4 0.4 0.043 14.3 0.4 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain SDA1 PF05285.12 GBG88199.1 - 0.014 14.8 22.8 0.016 14.6 22.8 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG88199.1 - 0.028 12.8 16.4 0.031 12.6 16.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 GBG88199.1 - 1.2 8.5 8.4 1.6 8.1 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vfa1 PF08432.10 GBG88199.1 - 2 8.7 8.2 2.8 8.2 8.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 GBG88199.1 - 5 5.2 29.9 6 4.9 29.9 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG88199.1 - 8.4 4.7 21.2 11 4.4 21.2 1.1 1 0 0 1 1 1 0 Mpp10 protein GCV_T PF01571.21 GBG88200.1 - 0.0024 17.3 0.0 1.7 8.0 0.0 3.0 1 1 1 2 2 2 2 Aminomethyltransferase folate-binding domain TPR_2 PF07719.17 GBG88201.1 - 4.2e-05 23.4 0.3 0.00014 21.8 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG88201.1 - 0.00073 19.3 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG88201.1 - 0.037 14.9 1.8 0.57 11.2 0.8 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4400 PF14348.6 GBG88202.1 - 0.15 11.5 2.9 0.22 11.0 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) DAGK_acc PF00609.19 GBG88203.1 - 9.6e-53 178.8 0.0 1.5e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 GBG88203.1 - 5.1e-24 84.3 0.0 1e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 GBG88203.1 - 3.4e-12 46.1 15.9 1.3e-08 34.6 4.8 2.7 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) hemP PF10636.9 GBG88203.1 - 0.091 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Hemin uptake protein hemP Leader_Trp PF08255.11 GBG88203.1 - 0.22 11.5 1.9 0.87 9.7 0.8 2.4 2 0 0 2 2 2 0 Trp-operon Leader Peptide zf-RING_9 PF13901.6 GBG88203.1 - 7.2 6.5 9.4 13 5.6 1.9 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon RT_RNaseH_2 PF17919.1 GBG88204.1 - 4.2e-10 39.6 0.1 7.8e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88204.1 - 2.1e-08 33.9 0.0 3.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG88204.1 - 0.036 12.3 9.3 0.043 12.0 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 GBG88204.1 - 0.12 12.5 12.5 0.17 12.0 12.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 GBG88204.1 - 0.66 8.2 12.4 0.92 7.7 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG88204.1 - 2.6 7.4 13.9 3.4 7.0 13.9 1.1 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG88205.1 - 4.4e-56 189.9 2.1 2.9e-27 95.6 0.0 4.7 5 0 0 5 5 5 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88205.1 - 3.5e-43 146.2 0.3 8.1e-21 74.3 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88205.1 - 6.6e-38 128.8 0.0 6.4e-22 77.5 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG88205.1 - 6.4e-06 26.0 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88205.1 - 7.8e-05 23.2 0.0 0.00023 21.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Lebercilin PF15619.6 GBG88205.1 - 0.00015 21.5 7.0 0.00015 21.5 7.0 5.9 4 2 2 6 6 6 1 Ciliary protein causing Leber congenital amaurosis disease gag-asp_proteas PF13975.6 GBG88205.1 - 0.0064 17.0 0.0 0.024 15.2 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88205.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG88206.1 - 0.036 14.7 0.2 1.7 9.3 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG88206.1 - 0.042 14.1 0.6 0.15 12.4 0.4 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein Chal_sti_synt_N PF00195.19 GBG88206.1 - 0.053 12.9 0.1 4.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain gag-asp_proteas PF13975.6 GBG88206.1 - 0.2 12.2 0.3 10 6.8 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TPD52 PF04201.15 GBG88206.1 - 2.2 7.9 8.6 2.1 8.0 0.2 3.1 3 0 0 3 3 3 0 Tumour protein D52 family Apc13p PF05839.11 GBG88206.1 - 3.6 7.8 6.8 19 5.5 4.9 2.6 2 0 0 2 2 2 0 Apc13p protein gag-asp_proteas PF13975.6 GBG88207.1 - 0.0018 18.8 0.0 0.0056 17.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88207.1 - 0.011 16.3 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG88207.1 - 0.035 13.9 0.6 0.12 12.2 0.0 2.1 3 0 0 3 3 3 0 Aspartyl protease RVP PF00077.20 GBG88207.1 - 0.089 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG88208.1 - 5.9e-20 71.2 0.4 5.4e-18 64.9 0.4 2.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Clathrin_propel PF01394.20 GBG88208.1 - 1e-16 60.3 0.5 2.4e-05 24.4 0.1 3.7 3 0 0 3 3 3 3 Clathrin propeller repeat RVT_1 PF00078.27 GBG88208.1 - 1.3e-16 60.8 0.1 2.5e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88208.1 - 4.6e-15 55.8 0.9 8.4e-13 48.5 0.9 2.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88208.1 - 8.5e-10 38.9 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Clathrin_H_link PF13838.6 GBG88209.1 - 1.1e-29 102.1 0.3 1.1e-29 102.1 0.3 2.1 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 GBG88209.1 - 4.4e-09 35.5 0.1 8.6e-09 34.6 0.1 1.5 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Clathrin_propel PF01394.20 GBG88209.1 - 7e-06 26.1 0.0 0.014 15.7 0.0 2.6 2 0 0 2 2 2 2 Clathrin propeller repeat PCEMA1 PF07418.11 GBG88209.1 - 0.00077 19.1 1.1 0.001 18.7 1.1 1.2 1 0 0 1 1 1 1 Acidic phosphoprotein precursor PCEMA1 TipAS PF07739.13 GBG88209.1 - 3.2 8.3 12.9 7.4 7.1 11.8 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Presenilin PF01080.17 GBG88209.1 - 6.5 5.4 6.6 11 4.7 6.6 1.3 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG88210.1 - 4.8e-29 101.5 0.1 7.5e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88210.1 - 4.7e-19 68.6 0.0 9.2e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88210.1 - 9e-19 67.4 0.0 1.8e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88210.1 - 1.5e-15 57.1 0.3 1.5e-15 57.1 0.3 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG88210.1 - 7.1e-08 32.3 0.0 1.8e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88210.1 - 1.9e-06 28.3 0.0 4.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88210.1 - 4.6e-06 27.2 0.0 1e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88210.1 - 0.001 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG88210.1 - 0.0057 16.8 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 GBG88211.1 - 3.8e-18 65.3 0.1 7.6e-18 64.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88211.1 - 4.6e-16 59.1 0.0 9e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG88211.1 - 0.016 15.4 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Clathrin PF00637.20 GBG88212.1 - 1.6e-45 154.5 2.0 3e-23 82.3 0.0 2.4 3 0 0 3 3 3 2 Region in Clathrin and VPS PHD_like PF12910.7 GBG88212.1 - 0.086 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system MBD PF01429.19 GBG88212.1 - 0.22 11.3 1.0 3.3 7.5 0.6 2.3 2 0 0 2 2 2 0 Methyl-CpG binding domain KASH_CCD PF14662.6 GBG88213.1 - 0.019 14.8 18.3 0.49 10.2 8.9 3.5 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Seryl_tRNA_N PF02403.22 GBG88213.1 - 0.034 14.4 17.5 0.78 10.0 5.1 3.9 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3287 PF11690.8 GBG88213.1 - 0.041 13.6 1.8 0.085 12.6 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) YabA PF06156.13 GBG88213.1 - 0.052 14.2 7.9 4.7 7.9 0.7 4.0 1 1 3 4 4 4 0 Initiation control protein YabA MbeD_MobD PF04899.12 GBG88213.1 - 0.13 12.4 6.4 1.1 9.4 1.4 3.4 3 0 0 3 3 3 0 MbeD/MobD like KIAA1430 PF13879.6 GBG88213.1 - 0.18 12.6 3.0 5.1 7.9 1.1 2.7 2 1 0 2 2 2 0 KIAA1430 homologue DUF5082 PF16888.5 GBG88213.1 - 0.2 11.9 8.7 0.19 12.0 1.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DivIC PF04977.15 GBG88213.1 - 0.38 10.5 21.9 0.062 13.1 1.1 4.9 4 1 1 5 5 5 0 Septum formation initiator eIF3_N PF09440.10 GBG88213.1 - 0.49 10.8 2.6 5.2 7.5 0.4 2.6 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF2680 PF10925.8 GBG88213.1 - 0.52 10.4 3.8 1.2 9.2 0.7 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2680) PCRF PF03462.18 GBG88213.1 - 0.95 9.3 8.8 1.3 8.9 0.5 2.7 2 1 1 3 3 3 0 PCRF domain Rotamase PF00639.21 GBG88213.1 - 1 10.4 4.0 1.6 9.7 1.4 2.3 2 1 0 2 2 2 0 PPIC-type PPIASE domain ZapB PF06005.12 GBG88213.1 - 1.3 9.6 25.4 15 6.1 6.1 5.1 4 1 0 4 4 3 0 Cell division protein ZapB Filament PF00038.21 GBG88213.1 - 1.3 8.5 20.6 0.15 11.6 6.2 2.6 1 1 1 2 2 2 0 Intermediate filament protein TMCO5 PF14992.6 GBG88213.1 - 1.5 8.3 12.4 0.054 13.1 2.0 2.2 1 1 1 2 2 2 0 TMCO5 family MCU PF04678.13 GBG88213.1 - 2 8.5 6.1 2.4 8.2 0.5 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CCDC92 PF14916.6 GBG88213.1 - 2.4 8.0 4.3 41 4.0 0.3 3.5 2 1 1 3 3 3 0 Coiled-coil domain of unknown function ERM PF00769.19 GBG88213.1 - 6 6.6 26.8 13 5.6 12.0 2.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2968 PF11180.8 GBG88213.1 - 6.1 6.4 11.6 1.2 8.7 1.0 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2968) YlqD PF11068.8 GBG88213.1 - 6.5 7.1 9.0 43 4.5 6.5 2.9 2 1 1 3 3 3 0 YlqD protein FlaC_arch PF05377.11 GBG88213.1 - 8.1 6.9 8.2 5.4 7.5 0.2 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) FAM76 PF16046.5 GBG88213.1 - 8.5 5.6 8.8 1.1 8.5 0.5 2.2 2 0 0 2 2 2 0 FAM76 protein DUF4407 PF14362.6 GBG88213.1 - 9.9 5.4 12.2 17 4.6 10.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Clathrin PF00637.20 GBG88214.1 - 1.9e-85 283.9 5.6 8.5e-31 106.8 0.0 3.6 3 0 0 3 3 3 3 Region in Clathrin and VPS RT_RNaseH PF17917.1 GBG88214.1 - 2.3e-13 50.3 0.3 6.3e-13 48.9 0.3 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88214.1 - 7.2e-13 48.8 0.1 1.9e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG88214.1 - 1.7e-05 24.8 0.1 4.2e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Coatomer_WDAD PF04053.14 GBG88214.1 - 4.5e-05 22.7 0.2 0.057 12.4 0.0 2.3 2 0 0 2 2 2 2 Coatomer WD associated region TPR_8 PF13181.6 GBG88214.1 - 0.00074 19.5 3.4 0.38 11.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 GBG88214.1 - 0.006 16.6 3.1 3.2 8.1 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG88214.1 - 0.012 16.4 0.9 9.6 7.3 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG88214.1 - 0.024 14.5 3.0 1.4 8.9 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1564 PF07600.11 GBG88214.1 - 0.049 13.3 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Clathrin PF00637.20 GBG88217.1 - 1.8e-50 170.5 9.1 8.5e-30 103.5 1.5 2.5 3 0 0 3 3 3 2 Region in Clathrin and VPS ASRT PF07100.11 GBG88217.1 - 0.0037 17.3 0.1 0.0075 16.3 0.1 1.4 1 0 0 1 1 1 1 Anabaena sensory rhodopsin transducer DpnII PF04556.12 GBG88217.1 - 0.0051 16.2 0.4 0.01 15.2 0.4 1.5 1 0 0 1 1 1 1 DpnII restriction endonuclease gag-asp_proteas PF13975.6 GBG88218.1 - 6.1e-07 29.9 0.0 1.4e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88218.1 - 4.9e-05 23.9 0.0 0.00014 22.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF1564 PF07600.11 GBG88218.1 - 0.00041 20.1 0.1 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Asp_protease PF09668.10 GBG88218.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG88218.1 - 0.0053 16.6 0.1 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Tmemb_cc2 PF10267.9 GBG88218.1 - 0.025 13.7 0.5 0.052 12.7 0.5 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Sporozoite_P67 PF05642.11 GBG88218.1 - 0.094 10.8 1.2 0.13 10.4 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RVP_2 PF08284.11 GBG88218.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4795 PF16043.5 GBG88218.1 - 0.32 10.6 4.0 0.12 11.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) MCU PF04678.13 GBG88218.1 - 1.4 9.0 6.5 4.6 7.3 2.0 2.6 2 1 0 2 2 2 0 Mitochondrial calcium uniporter RRM_1 PF00076.22 GBG88219.1 - 1.4e-54 181.7 0.1 5.4e-19 67.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG88219.1 - 4.5e-08 33.1 0.1 0.0054 16.8 0.0 4.0 3 2 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 GBG88219.1 - 0.00035 20.5 0.0 0.29 11.2 0.0 2.7 2 0 0 2 2 2 2 RNA binding domain RRM_3 PF08777.11 GBG88219.1 - 0.0026 17.8 0.1 1 9.4 0.0 2.6 3 0 0 3 3 3 2 RNA binding motif BRAP2 PF07576.12 GBG88219.1 - 0.0033 17.6 0.0 3.6 7.9 0.0 3.0 3 0 0 3 3 3 1 BRCA1-associated protein 2 Nup35_RRM PF05172.13 GBG88219.1 - 0.01 15.8 0.1 18 5.4 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 GBG88219.1 - 0.011 15.7 0.1 19 5.4 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 GBG88219.1 - 0.099 12.7 0.0 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 Cohesin_load PF10345.9 GBG88220.1 - 1.1e-24 86.9 0.1 1.8e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 GBG88220.1 - 1.3e-11 44.7 3.9 0.00078 19.7 0.0 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 GBG88220.1 - 3e-05 23.8 3.2 2.5 8.4 0.0 6.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG88220.1 - 0.001 19.7 4.9 0.46 11.4 0.2 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG88220.1 - 0.0013 18.6 0.3 0.31 11.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC5 PF12862.7 GBG88220.1 - 0.0046 17.0 0.2 2.8 8.1 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_16 PF13432.6 GBG88220.1 - 0.061 14.0 0.3 26 5.5 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG88220.1 - 0.12 13.0 0.5 2.9e+02 2.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG88220.1 - 0.13 12.2 0.4 38 4.3 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG88220.1 - 1.8 8.8 4.8 19 5.6 0.0 4.3 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 RT_RNaseH PF17917.1 GBG88221.1 - 3.6e-08 33.6 0.0 2.6e-07 30.9 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88221.1 - 3.4e-07 30.2 0.0 9.3e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Diphthami_syn_2 PF01902.17 GBG88221.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Diphthamide synthase ACT_3 PF10000.9 GBG88221.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 ACT domain RVT_1 PF00078.27 GBG88222.1 - 3.2e-06 26.8 0.0 2.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG88222.1 - 0.00096 19.7 0.0 0.0022 18.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88222.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4913 PF16259.5 GBG88223.1 - 0.13 12.3 0.4 2.6 8.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) DUF659 PF04937.15 GBG88224.1 - 2.2e-17 63.3 0.0 4.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG88225.1 - 1.1e-28 100.3 0.0 1.8e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88225.1 - 6.5e-28 96.7 0.0 1.7e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88225.1 - 2.3e-25 88.9 0.0 5.3e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88225.1 - 3e-17 62.5 1.2 4.7e-17 61.9 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG88225.1 - 2.1e-06 28.2 0.0 3.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88225.1 - 6.1e-06 26.1 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88225.1 - 1.8e-05 25.3 0.0 3.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88225.1 - 0.038 13.8 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG88226.1 - 1.1e-06 29.1 0.0 2.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88226.1 - 1.6e-05 25.4 0.0 4.5e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88226.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88226.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG88226.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1996 PF09362.10 GBG88227.1 - 0.31 11.0 1.0 0.38 10.7 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1996) RVT_1 PF00078.27 GBG88228.1 - 1.9e-26 93.0 0.0 3.5e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88228.1 - 1.5e-20 73.0 0.0 4.6e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88228.1 - 9.9e-11 41.9 0.0 2.7e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG88228.1 - 0.0054 17.0 0.1 0.14 12.5 0.1 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG88228.1 - 0.068 13.4 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Baculo_PEP_C PF04513.12 GBG88228.1 - 0.19 11.8 1.0 0.89 9.6 1.3 2.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 GBG88228.1 - 0.4 11.2 3.7 9.8 6.7 0.7 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein RT_RNaseH PF17917.1 GBG88231.1 - 4.3e-28 97.7 0.1 1e-27 96.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88231.1 - 4.1e-24 84.5 0.0 9.1e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88231.1 - 4.9e-14 52.5 0.1 9.9e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG88231.1 - 0.0071 16.2 0.1 0.043 13.7 0.0 2.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG88231.1 - 0.014 15.1 0.5 0.052 13.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG88232.1 - 6.2e-66 222.1 0.6 2e-35 122.4 0.1 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88232.1 - 2.8e-48 162.5 0.1 1.2e-28 99.4 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88232.1 - 8.1e-42 141.3 0.0 1.7e-28 98.6 0.0 3.2 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88232.1 - 2.9e-13 49.7 1.3 6.6e-13 48.6 1.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Melibiase_2 PF16499.5 GBG88232.1 - 4.4e-13 49.0 0.2 1.9e-12 46.9 0.2 2.0 3 0 0 3 3 3 1 Alpha galactosidase A Asp_protease_2 PF13650.6 GBG88232.1 - 0.00014 22.4 0.0 0.00034 21.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88232.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG88232.1 - 0.0085 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1758 PF05585.12 GBG88232.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) FPV060 PF17614.2 GBG88232.1 - 0.02 14.2 0.1 0.044 13.2 0.1 1.5 1 0 0 1 1 1 0 Viral CC-type chemokine DUF421 PF04239.12 GBG88232.1 - 0.033 14.0 0.2 0.089 12.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF421) BLOC1_2 PF10046.9 GBG88232.1 - 0.11 12.8 4.9 0.27 11.6 2.4 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4392 PF14336.6 GBG88232.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) gag-asp_proteas PF13975.6 GBG88232.1 - 0.17 12.5 0.0 0.6 10.7 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease NPV_P10 PF05531.12 GBG88232.1 - 0.52 10.8 4.6 4.7 7.8 0.2 3.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GBG88232.1 - 1.3 8.3 10.7 3.8 6.8 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2408 PF10303.9 GBG88232.1 - 2.3 8.8 6.3 0.91 10.1 0.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Phage_GPO PF05929.11 GBG88232.1 - 8.2 6.0 9.1 4.3 6.9 0.0 2.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4187 PF13821.6 GBG88233.1 - 0.004 16.9 0.5 0.011 15.5 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG88233.1 - 0.0048 17.1 0.2 0.0048 17.1 0.2 3.2 3 1 1 4 4 4 1 Retrotransposon gag protein rve PF00665.26 GBG88234.1 - 2.9e-26 92.0 0.0 6e-15 55.5 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH PF17917.1 GBG88234.1 - 2.4e-21 76.0 0.1 5e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88234.1 - 3.7e-14 52.6 1.5 1.2e-13 50.9 1.5 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG88234.1 - 1.4e-12 47.5 0.0 3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG88234.1 - 2.1e-10 40.3 0.0 4.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Melibiase_C PF17801.1 GBG88234.1 - 3.8e-09 36.5 0.8 1.2e-08 34.9 0.8 1.8 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain zf-H2C2 PF09337.10 GBG88234.1 - 0.0074 16.5 0.2 0.017 15.3 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger ZapB PF06005.12 GBG88235.1 - 0.029 14.8 0.0 0.029 14.8 0.0 3.7 2 2 0 2 2 2 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 GBG88235.1 - 0.059 13.6 18.6 1.2 9.4 9.7 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 GBG88235.1 - 0.12 12.9 1.5 0.8 10.2 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-C4H2 PF10146.9 GBG88235.1 - 2.9 8.1 8.3 2.5 8.4 0.2 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein Spore_III_AF PF09581.10 GBG88235.1 - 6.3 6.8 8.1 2.1 8.3 5.2 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) CsgE PF10627.9 GBG88235.1 - 7.8 6.8 7.4 23 5.3 7.4 1.9 1 1 0 1 1 1 0 Curli assembly protein CsgE DUF659 PF04937.15 GBG88236.1 - 3e-38 131.1 0.0 5.7e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88236.1 - 1e-06 28.4 1.5 2.4e-06 27.3 1.5 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Lactamase_B PF00753.27 GBG88237.1 - 2.7e-05 24.3 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Flavin_Reduct PF01613.18 GBG88237.1 - 0.0079 16.2 0.0 0.033 14.2 0.0 2.1 2 0 0 2 2 2 1 Flavin reductase like domain Lactamase_B_2 PF12706.7 GBG88237.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Flavodoxin_1 PF00258.25 GBG88237.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin zf-CCHC PF00098.23 GBG88237.1 - 0.64 10.2 3.4 1.7 8.9 3.4 1.8 1 0 0 1 1 1 0 Zinc knuckle Flavin_Reduct PF01613.18 GBG88238.1 - 1.2e-10 41.7 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Lactamase_B_3 PF13483.6 GBG88239.1 - 4.4e-26 91.7 0.0 6.2e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 GBG88239.1 - 0.0015 18.1 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_34 PF05637.12 GBG88240.1 - 7.4e-23 81.5 0.0 2.9e-22 79.6 0.0 1.8 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF4360 PF14273.6 GBG88245.1 - 8.1e-47 159.4 0.0 9.2e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MucBP PF06458.12 GBG88245.1 - 0.0067 17.4 0.9 0.35 11.9 0.7 2.5 1 1 1 2 2 2 1 MucBP domain DDE_Tnp_4 PF13359.6 GBG88246.1 - 2.1e-29 102.2 0.0 3.9e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88246.1 - 9.3e-15 54.8 0.0 1.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein rve PF00665.26 GBG88246.1 - 1.7e-07 31.5 0.1 5.1e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG88246.1 - 0.00029 20.7 0.8 0.00053 19.8 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG88246.1 - 0.0069 16.6 1.3 0.017 15.4 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DDE_Tnp_1 PF01609.21 GBG88246.1 - 0.046 13.4 5.4 0.52 9.9 0.0 3.5 3 0 0 3 3 3 0 Transposase DDE domain DUF4366 PF14283.6 GBG88246.1 - 0.23 11.5 2.0 0.62 10.1 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4360 PF14273.6 GBG88247.1 - 1.2e-46 158.8 0.0 1.4e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MucBP PF06458.12 GBG88247.1 - 0.0067 17.4 0.9 0.35 11.9 0.7 2.5 1 1 1 2 2 2 1 MucBP domain HATPase_c PF02518.26 GBG88248.1 - 5e-27 94.6 0.0 1.8e-26 92.8 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sulfate_transp PF00916.20 GBG88248.1 - 6.3e-17 61.4 1.8 1.1e-16 60.6 1.8 1.3 1 0 0 1 1 1 1 Sulfate permease family Integrase_H2C2 PF17921.1 GBG88248.1 - 1.4e-14 53.9 0.5 3.1e-14 52.8 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG88248.1 - 5.5e-09 36.2 1.6 2.6e-08 34.1 0.5 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HATPase_c_3 PF13589.6 GBG88248.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GBG88248.1 - 0.0062 16.6 0.3 0.019 15.0 0.3 1.8 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 GBG88248.1 - 0.01 15.8 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain RT_RNaseH_2 PF17919.1 GBG88249.1 - 6.5e-33 112.7 0.0 1.5e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88249.1 - 8.7e-28 96.7 0.0 2.1e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88249.1 - 1.9e-25 89.7 0.0 3.5e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG88249.1 - 0.019 15.2 0.0 0.068 13.4 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain PUF PF00806.19 GBG88249.1 - 0.11 12.3 0.0 22 5.0 0.0 2.8 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat RVP_2 PF08284.11 GBG88250.1 - 7.8e-06 25.7 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG88250.1 - 1.5e-05 24.9 3.0 1.5e-05 24.9 3.0 2.0 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG88250.1 - 0.00036 21.0 0.1 0.00081 19.9 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88250.1 - 0.0025 18.4 0.0 0.006 17.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG88250.1 - 0.017 14.9 4.1 0.031 14.1 4.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 GBG88250.1 - 0.045 13.5 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG88251.1 - 2.7e-08 33.8 0.2 4.1e-08 33.2 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88251.1 - 0.0012 19.0 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 H2C2 zinc finger Nop53 PF07767.11 GBG88251.1 - 0.15 11.4 15.5 0.21 10.9 15.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Na_trans_assoc PF06512.13 GBG88251.1 - 0.71 10.1 11.3 1.3 9.2 11.3 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG88251.1 - 5.7 5.0 22.5 7.4 4.7 22.5 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG88251.1 - 9.7 5.5 23.1 13 5.1 23.1 1.1 1 0 0 1 1 1 0 SDA1 RT_RNaseH_2 PF17919.1 GBG88252.1 - 5.6e-31 106.5 0.0 1.1e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88252.1 - 1.7e-30 105.4 0.0 4.1e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88252.1 - 0.028 14.0 0.1 0.055 13.0 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Casc1_N PF15927.5 GBG88252.1 - 0.07 12.8 15.5 0.18 11.5 15.5 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Phage_GPO PF05929.11 GBG88252.1 - 0.28 10.8 0.1 0.28 10.8 0.1 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase CHD5 PF04420.14 GBG88252.1 - 0.42 10.5 3.6 0.94 9.3 3.6 1.5 1 0 0 1 1 1 0 CHD5-like protein Nckap1 PF09735.9 GBG88253.1 - 0.031 12.2 0.0 0.46 8.4 0.0 1.9 2 0 0 2 2 2 0 Membrane-associated apoptosis protein RT_RNaseH_2 PF17919.1 GBG88254.1 - 2.7e-28 98.0 0.0 2.6e-14 53.1 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88254.1 - 7.3e-28 97.6 0.1 1.1e-27 97.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88254.1 - 1e-27 96.5 0.0 2.1e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88254.1 - 3e-11 43.2 0.0 3e-11 43.2 0.0 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88254.1 - 0.0098 16.1 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DarA_C PF18789.1 GBG88255.1 - 0.054 13.8 1.9 12 6.3 1.9 2.9 1 1 0 1 1 1 0 Defence against restriction A C-terminal RVT_1 PF00078.27 GBG88257.1 - 2.9e-22 79.3 0.2 3.9e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88257.1 - 6.9e-12 45.3 0.0 1.8e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88257.1 - 0.00075 19.7 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Tcp11 PF05794.13 GBG88258.1 - 9.3e-53 179.9 1.9 6.4e-35 121.1 1.0 2.3 2 0 0 2 2 2 2 T-complex protein 11 Peptidase_C26 PF07722.13 GBG88259.1 - 7.3e-16 58.6 0.0 4.4e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 GBG88259.1 - 0.00064 19.5 0.0 0.0018 18.0 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I zf-RING_13 PF17977.1 GBG88260.1 - 0.022 14.9 5.7 0.045 13.9 0.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Retrotrans_gag PF03732.17 GBG88261.1 - 7.6e-05 22.9 0.7 0.0014 18.8 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Phage_lysozyme PF00959.19 GBG88261.1 - 0.095 13.2 0.1 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Phage lysozyme RT_RNaseH_2 PF17919.1 GBG88263.1 - 3.1e-33 113.8 0.0 5e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88263.1 - 6.4e-30 103.5 0.2 1.1e-29 102.8 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rab3-GTPase_cat PF13890.6 GBG88263.1 - 0.081 12.5 0.1 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit RGCC PF15151.6 GBG88263.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Response gene to complement 32 protein family RT_RNaseH PF17917.1 GBG88264.1 - 1.3e-21 76.8 0.0 2.5e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88264.1 - 2.2e-20 72.5 0.0 3.9e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88264.1 - 3.5e-19 68.7 0.9 1.2e-18 67.0 0.9 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain LRR_8 PF13855.6 GBG88264.1 - 3.9e-05 23.3 6.1 0.0028 17.4 0.3 2.7 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GBG88264.1 - 0.00012 22.4 9.8 1.6 9.2 0.0 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GBG88264.1 - 0.0034 17.6 2.6 0.006 16.9 1.5 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Crp PF00325.20 GBG88264.1 - 0.03 14.0 49.8 15 5.3 0.0 23.1 20 7 11 31 31 31 0 Bacterial regulatory proteins, crp family zf-H2C2 PF09337.10 GBG88264.1 - 0.065 13.5 0.2 0.33 11.2 0.2 2.4 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG88265.1 - 4.4e-27 95.0 0.0 6.9e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88265.1 - 2e-25 88.8 0.1 4.4e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88265.1 - 5.9e-20 71.1 0.1 1.3e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG88265.1 - 9.6e-15 54.8 0.4 1.5e-11 44.5 0.0 2.7 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88265.1 - 1.4e-07 31.7 0.1 7.6e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG88265.1 - 0.0029 17.8 0.0 0.012 15.8 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger FtsK_4TM PF13491.6 GBG88265.1 - 0.077 12.7 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE IHABP4_N PF16174.5 GBG88265.1 - 0.83 10.2 4.4 1.5 9.4 4.4 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal LYRIC PF15686.5 GBG88265.1 - 1.8 8.0 4.9 2.6 7.5 4.9 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Rrn6 PF10214.9 GBG88265.1 - 3 6.2 9.0 4.2 5.7 9.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM199X PF15814.5 GBG88265.1 - 6 5.8 6.6 10 5.0 6.6 1.3 1 0 0 1 1 1 0 Protein family FAM199X RVT_1 PF00078.27 GBG88266.1 - 4.5e-30 104.8 0.1 1.1e-29 103.5 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88266.1 - 2.4e-25 88.5 0.0 6.8e-25 87.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88266.1 - 9.9e-15 54.7 0.0 2.5e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG88266.1 - 2.5e-07 31.2 0.0 6.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88266.1 - 7e-07 29.7 0.0 2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88266.1 - 8e-07 28.9 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG88266.1 - 2.3e-05 24.6 3.1 0.0008 19.6 0.0 4.0 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG88266.1 - 0.00022 21.0 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease SPACA9 PF15120.6 GBG88266.1 - 0.13 12.0 0.3 0.48 10.2 0.3 1.9 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 NPV_P10 PF05531.12 GBG88266.1 - 0.35 11.4 1.2 8 7.0 0.1 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.16 GBG88266.1 - 0.82 8.5 3.0 1.6 7.5 2.8 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF4407 PF14362.6 GBG88266.1 - 1 8.7 14.6 1.1 8.5 6.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-Tim10_DDP PF02953.15 GBG88268.1 - 3.7e-19 68.1 2.8 5e-19 67.7 2.7 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 GBG88268.1 - 0.028 14.1 2.9 0.057 13.1 2.9 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF3509 PF12021.8 GBG88268.1 - 0.086 12.6 0.2 0.29 10.9 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3509) DUF5388 PF17363.2 GBG88268.1 - 0.12 12.6 0.0 1.3 9.2 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5388) MCRS_N PF13325.6 GBG88269.1 - 1.5e-09 38.2 0.0 4.2e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 N-terminal region of micro-spherule protein FHA PF00498.26 GBG88269.1 - 8.5e-06 26.0 0.1 2.6e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 FHA domain FAM177 PF14774.6 GBG88270.1 - 0.0005 20.4 0.0 0.00076 19.8 0.0 1.4 1 0 0 1 1 1 1 FAM177 family LRR_6 PF13516.6 GBG88271.1 - 1.1e-10 40.6 13.8 0.047 13.8 0.2 8.4 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 GBG88271.1 - 1.2e-07 32.0 1.5 0.14 12.6 0.0 5.3 3 2 0 4 4 4 2 Leucine Rich repeats (2 copies) Sigma70_ner PF04546.13 GBG88271.1 - 0.00049 20.0 2.3 0.00094 19.1 1.7 1.8 2 0 0 2 2 2 1 Sigma-70, non-essential region BSP_II PF05432.11 GBG88271.1 - 0.0064 16.2 12.8 0.0091 15.7 12.8 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 GBG88271.1 - 0.017 13.3 13.8 0.023 12.8 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi LRR_8 PF13855.6 GBG88271.1 - 0.043 13.6 0.7 4.6 7.1 0.1 3.7 3 1 1 4 4 4 0 Leucine rich repeat TFB6 PF17110.5 GBG88271.1 - 0.049 13.4 1.0 0.079 12.7 1.0 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Fmp27 PF10344.9 GBG88271.1 - 0.14 10.2 0.5 0.19 9.8 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 RXT2_N PF08595.11 GBG88271.1 - 0.17 11.9 5.1 0.28 11.2 5.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 GBG88271.1 - 0.18 11.2 12.2 0.34 10.2 12.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 GBG88271.1 - 0.24 10.7 7.7 0.39 10.0 7.7 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 GBG88271.1 - 0.28 9.7 1.7 0.4 9.2 1.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_3_Rpc31 PF11705.8 GBG88271.1 - 0.29 11.3 15.4 0.45 10.7 15.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 F-box-like PF12937.7 GBG88271.1 - 0.41 10.6 0.0 0.41 10.6 0.0 2.3 3 0 0 3 3 1 0 F-box-like PPP4R2 PF09184.11 GBG88271.1 - 0.44 10.1 12.3 0.73 9.4 12.3 1.3 1 0 0 1 1 1 0 PPP4R2 Usp PF00582.26 GBG88271.1 - 0.45 11.0 4.7 0.96 9.9 4.7 1.5 1 0 0 1 1 1 0 Universal stress protein family FAM176 PF14851.6 GBG88271.1 - 0.84 9.3 10.5 1.5 8.5 10.5 1.3 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 GBG88271.1 - 1.1 9.4 4.8 0.43 10.7 2.2 1.6 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal Radial_spoke PF04712.12 GBG88271.1 - 1.5 7.7 16.0 2.1 7.2 16.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein S-antigen PF05756.11 GBG88271.1 - 1.5 9.2 4.5 3 8.3 4.5 1.4 1 0 0 1 1 1 0 S-antigen protein Prothymosin PF03247.14 GBG88271.1 - 2 8.9 31.8 3.3 8.2 31.8 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family SKA1 PF07160.12 GBG88271.1 - 2.7 7.8 7.1 14 5.5 0.0 2.9 3 0 0 3 3 2 0 Spindle and kinetochore-associated protein 1 DUF2052 PF09747.9 GBG88271.1 - 2.7 8.1 18.7 4.4 7.4 18.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PTPRCAP PF15713.5 GBG88271.1 - 3.1 8.1 15.8 5.9 7.2 15.8 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated NOA36 PF06524.12 GBG88271.1 - 4.1 6.6 15.8 9.9 5.4 15.8 1.6 1 0 0 1 1 1 0 NOA36 protein LRR_1 PF00560.33 GBG88271.1 - 4.5 8.2 8.8 78 4.4 0.0 6.1 8 0 0 8 8 5 0 Leucine Rich Repeat Tim54 PF11711.8 GBG88271.1 - 4.8 5.9 7.0 7 5.3 7.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Mpp10 PF04006.12 GBG88271.1 - 5.9 5.2 18.4 9.3 4.6 18.4 1.2 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 GBG88271.1 - 8.4 6.1 10.3 13 5.5 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG88271.1 - 8.4 5.7 17.0 12 5.2 17.0 1.1 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 GBG88271.1 - 9.9 6.6 14.3 19 5.7 14.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCFC PF07842.12 GBG88272.1 - 5.5e-23 82.0 0.6 5.6e-22 78.7 0.6 2.2 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein CENP-T_C PF15511.6 GBG88273.1 - 1.5e-08 34.7 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GBG88273.1 - 3.1e-05 24.2 0.1 5e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 GBG88273.1 - 0.0029 17.7 0.1 0.0042 17.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 GBG88273.1 - 0.0046 17.3 0.2 0.0054 17.1 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 GBG88273.1 - 0.0049 16.9 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 GBG88273.1 - 0.0056 16.9 0.1 0.0092 16.2 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GBG88273.1 - 0.021 14.9 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit ABC_tran PF00005.27 GBG88274.1 - 7.1e-24 84.9 0.0 1.3e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GBG88274.1 - 2e-09 37.2 11.9 2e-09 37.2 11.9 1.6 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 GBG88274.1 - 3.6e-05 23.7 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GBG88274.1 - 7.7e-05 22.7 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 GBG88274.1 - 0.0058 16.2 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GBG88274.1 - 0.015 15.6 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GBG88274.1 - 0.021 15.2 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 GBG88274.1 - 0.028 14.2 0.3 0.07 12.9 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 GBG88274.1 - 0.067 12.9 2.9 0.076 12.7 0.5 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 GBG88274.1 - 0.092 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 GBG88274.1 - 0.11 12.1 0.3 0.18 11.4 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 GBG88274.1 - 0.12 12.8 0.5 0.21 12.0 0.5 1.3 1 0 0 1 1 1 0 AAA domain Rhodopsin_N PF10413.9 GBG88274.1 - 0.15 11.9 0.3 0.33 10.8 0.3 1.5 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin AAA_33 PF13671.6 GBG88274.1 - 0.18 11.9 0.6 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 GBG88274.1 - 0.2 11.0 0.1 0.98 8.7 0.2 1.9 2 0 0 2 2 2 0 KaiC ABC_ATPase PF09818.9 GBG88274.1 - 0.3 9.8 0.6 0.49 9.1 0.6 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 GBG88274.1 - 1.7 8.8 4.9 0.76 10.0 0.7 2.1 2 0 0 2 2 2 0 AAA domain Mannosyl_trans2 PF04188.13 GBG88275.1 - 2e-18 66.9 1.4 2.3e-18 66.8 1.4 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) DIE2_ALG10 PF04922.12 GBG88275.1 - 0.0014 18.0 0.2 0.0015 17.9 0.2 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family DUF659 PF04937.15 GBG88276.1 - 1.8e-11 44.1 0.0 1.7e-10 41.0 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88276.1 - 8.7e-09 35.1 0.1 2.1e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG88278.1 - 5.3e-23 81.0 0.0 2e-22 79.1 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88278.1 - 2.3e-22 79.3 0.0 7.2e-22 77.7 0.0 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88278.1 - 6.6e-18 65.0 0.1 4.1e-12 46.1 0.0 2.7 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88278.1 - 2.1e-17 63.0 0.5 5.9e-17 61.5 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88278.1 - 2.6e-09 37.3 0.3 8.5e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG88278.1 - 1.3e-05 25.8 0.0 2.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88278.1 - 5.8e-05 23.6 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88278.1 - 0.00026 20.7 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88278.1 - 0.0017 18.1 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG88278.1 - 0.013 15.7 8.7 0.03 14.6 0.0 4.2 4 0 0 4 4 4 0 Retrotransposon gag protein DUF421 PF04239.12 GBG88278.1 - 0.18 11.6 0.1 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF421) GIT_CC PF16559.5 GBG88278.1 - 5.2 7.0 8.5 88 3.1 0.1 3.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Snapin_Pallidin PF14712.6 GBG88278.1 - 8.4 6.9 13.4 0.16 12.4 3.2 3.2 4 0 0 4 4 4 0 Snapin/Pallidin CRF PF00473.17 GBG88278.1 - 9.3 6.4 8.4 12 6.0 0.4 3.1 2 0 0 2 2 2 0 Corticotropin-releasing factor family DUF3522 PF12036.8 GBG88279.1 - 1.5e-12 48.2 5.6 1.9e-12 47.9 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF4345 PF14248.6 GBG88279.1 - 0.041 13.8 0.6 0.25 11.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) B56 PF01603.20 GBG88279.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) MerC PF03203.14 GBG88279.1 - 0.27 11.7 5.2 0.13 12.8 1.9 2.0 1 1 1 2 2 2 0 MerC mercury resistance protein ResB PF05140.14 GBG88281.1 - 3.1e-77 260.4 0.0 1.8e-61 208.4 0.0 2.1 1 1 1 2 2 2 2 ResB-like family Menin PF05053.13 GBG88283.1 - 2.6 6.3 9.6 3.2 6.0 9.6 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 GBG88283.1 - 10 4.6 10.2 13 4.2 10.2 1.0 1 0 0 1 1 1 0 Macoilin family F-box-like PF12937.7 GBG88284.1 - 1.1e-10 41.2 1.2 2.7e-10 40.0 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG88284.1 - 8.2e-06 25.6 1.5 1.5e-05 24.7 1.5 1.4 1 0 0 1 1 1 1 F-box domain Herpes_UL92 PF03048.14 GBG88284.1 - 0.0016 18.2 2.1 0.0027 17.5 2.1 1.2 1 0 0 1 1 1 1 UL92 family PK PF00224.21 GBG88285.1 - 5.9e-146 485.8 1.1 7.1e-146 485.5 1.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GBG88285.1 - 3.3e-18 66.0 0.7 1.3e-17 64.1 0.1 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain Ciart PF15673.5 GBG88285.1 - 0.028 13.8 0.1 0.047 13.1 0.1 1.3 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor HpcH_HpaI PF03328.14 GBG88285.1 - 0.12 11.5 0.2 0.35 10.0 0.1 1.6 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Cuticle_1 PF08140.11 GBG88285.1 - 0.13 12.3 0.1 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Crustacean cuticle protein repeat Ribosomal_L29 PF00831.23 GBG88286.1 - 1.1e-18 66.9 1.6 1.1e-18 66.9 1.6 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 GBG88286.1 - 0.21 12.0 4.7 0.14 12.5 2.8 1.6 1 1 1 2 2 2 0 Snapin/Pallidin Myb_DNA-bind_4 PF13837.6 GBG88288.1 - 0.00011 22.5 3.3 0.00026 21.3 0.4 2.9 4 0 0 4 4 4 1 Myb/SANT-like DNA-binding domain SR-25 PF10500.9 GBG88289.1 - 1e-07 31.8 53.6 5.1e-06 26.3 21.9 2.1 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 GBG88289.1 - 0.019 15.2 32.1 0.17 12.2 8.0 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Lin-8 PF03353.15 GBG88289.1 - 7.4 6.0 17.7 4.9 6.6 2.8 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist LON_substr_bdg PF02190.16 GBG88290.1 - 4.9e-10 39.6 0.0 1.2e-09 38.4 0.0 1.6 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain CytochromB561_N PF09786.9 GBG88290.1 - 1.7 7.5 12.9 2.7 6.9 12.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal VASt PF16016.5 GBG88291.1 - 6.5e-25 88.3 1.3 1e-24 87.7 1.3 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain C2 PF00168.30 GBG88291.1 - 8e-15 55.0 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain GRAM PF02893.20 GBG88291.1 - 2.8e-14 53.0 0.2 1.7e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 GRAM domain Pkinase PF00069.25 GBG88292.1 - 1.5e-78 263.8 0.0 2.3e-78 263.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG88292.1 - 3.7e-47 160.8 0.0 5.9e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG88292.1 - 4.1e-08 32.9 0.0 6e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 GBG88292.1 - 0.00015 20.6 0.0 0.00033 19.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 GBG88292.1 - 0.005 16.5 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GBG88292.1 - 0.005 16.8 0.2 0.005 16.8 0.2 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 GBG88292.1 - 0.006 16.0 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GBG88292.1 - 0.0081 15.8 0.1 0.028 14.1 0.0 1.9 2 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GBG88292.1 - 0.015 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 GBG88292.1 - 0.046 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Arm PF00514.23 GBG88293.1 - 2.5e-11 43.2 0.0 1.6e-06 27.9 0.0 3.8 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GBG88293.1 - 3.9e-11 42.2 0.0 0.0024 18.0 0.0 3.8 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.6 GBG88293.1 - 1.8e-09 37.9 0.1 2.9e-06 27.6 0.0 2.6 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 GBG88293.1 - 1.4e-07 31.9 0.0 2.1e-05 24.9 0.0 3.5 1 1 2 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 GBG88293.1 - 0.0012 18.9 0.0 0.0072 16.4 0.0 2.0 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 JAB PF01398.21 GBG88295.1 - 1.1e-26 93.1 0.1 2.2e-26 92.1 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BRCC36_C PF18110.1 GBG88295.1 - 6.8e-22 77.4 0.3 1.2e-21 76.6 0.3 1.4 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain Prok-JAB PF14464.6 GBG88295.1 - 1.4e-10 40.9 0.9 2.9e-10 39.9 0.3 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Herpes_pp85 PF04637.12 GBG88295.1 - 0.35 9.2 6.8 0.5 8.7 6.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CNDH2_M PF16869.5 GBG88295.1 - 0.88 10.3 7.6 4.3 8.0 1.3 2.6 2 0 0 2 2 2 0 PF16858 Methyltransf_12 PF08242.12 GBG88296.1 - 0.22 12.3 5.5 3.8 8.3 0.3 2.6 2 0 0 2 2 2 0 Methyltransferase domain Mpp10 PF04006.12 GBG88296.1 - 1.3 7.4 13.6 0.21 10.0 7.2 1.9 2 0 0 2 2 2 0 Mpp10 protein RT_RNaseH PF17917.1 GBG88297.1 - 9.7e-22 77.2 0.2 2.8e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88297.1 - 9e-20 70.6 0.0 2.1e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88297.1 - 9.5e-20 70.5 0.2 1.9e-19 69.5 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88297.1 - 1.2e-10 41.6 0.0 4.7e-10 39.7 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG88297.1 - 1.9e-08 34.9 0.0 1.4e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG88297.1 - 2.7e-08 33.6 0.0 5.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88297.1 - 1.2e-06 29.0 0.0 5e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88297.1 - 0.0042 16.9 0.0 0.009 15.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG88297.1 - 0.0061 16.8 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG88297.1 - 0.0066 16.0 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG88297.1 - 0.035 14.3 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger PPP4R2 PF09184.11 GBG88298.1 - 0.018 14.6 22.0 0.02 14.5 22.0 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 GBG88298.1 - 2.7 7.9 25.3 2.8 7.8 25.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 GBG88298.1 - 2.9 7.8 7.0 4 7.4 7.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Drc1-Sld2 PF11719.8 GBG88298.1 - 5 6.6 20.8 5.4 6.4 20.8 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF913 PF06025.12 GBG88298.1 - 6.9 5.5 8.4 7.4 5.4 8.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RVT_1 PF00078.27 GBG88299.1 - 9.9e-32 110.2 0.1 1.6e-31 109.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG88299.1 - 2.3e-05 24.8 0.0 5.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88299.1 - 0.0008 20.0 0.0 0.0022 18.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88299.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 GBG88299.1 - 0.0043 16.8 0.1 0.0097 15.7 0.1 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) BTRD1 PF17660.1 GBG88299.1 - 0.13 12.1 0.0 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 RVT_1 PF00078.27 GBG88300.1 - 2.9e-34 118.5 0.0 4.2e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88300.1 - 1.6e-21 76.2 0.0 3.4e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88300.1 - 2.4e-12 47.1 0.0 4.9e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG88300.1 - 3.4e-08 33.7 0.0 6.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1772 PF08592.11 GBG88301.1 - 0.03 14.6 0.1 0.091 13.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Phi29_Phage_SSB PF17427.2 GBG88301.1 - 4.6 7.5 10.2 5.3 7.2 4.3 2.4 1 1 1 2 2 2 0 Phage Single-stranded DNA-binding protein RVT_1 PF00078.27 GBG88302.1 - 2.5e-28 99.1 0.0 4.3e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exonuc_VII_L PF02601.15 GBG88302.1 - 0.26 10.8 4.8 0.59 9.7 4.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-CCHC PF00098.23 GBG88304.1 - 0.42 10.8 2.5 0.74 10.0 2.5 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG88305.1 - 1.7e-34 119.3 0.1 3.3e-34 118.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88305.1 - 4.7e-17 62.2 1.9 8.9e-17 61.3 0.5 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88305.1 - 6.2e-14 51.8 0.3 3.1e-07 30.3 0.2 3.0 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88305.1 - 0.017 15.2 0.0 0.044 13.9 0.0 1.8 1 0 0 1 1 1 0 Integrase zinc binding domain PCEMA1 PF07418.11 GBG88305.1 - 2.2 7.7 13.1 3.7 7.0 13.1 1.3 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 zf-CCHC PF00098.23 GBG88306.1 - 0.0054 16.7 3.3 0.0054 16.7 3.3 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG88306.1 - 0.0086 15.9 1.9 0.0086 15.9 1.9 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG88306.1 - 0.13 12.0 0.5 0.32 10.7 0.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger MethyltransfD12 PF02086.15 GBG88306.1 - 0.43 10.2 3.7 0.59 9.8 3.7 1.1 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase NARP1 PF12569.8 GBG88306.1 - 0.43 9.4 9.2 0.6 9.0 9.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 GBG88306.1 - 6.5 6.8 7.1 82 3.2 8.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Alanine_zipper PF11839.8 GBG88307.1 - 0.0019 18.5 18.3 0.0047 17.3 18.3 1.6 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein Lentiviral_Tat PF02998.14 GBG88307.1 - 1.1 9.3 7.0 2.3 8.3 0.1 3.6 3 0 0 3 3 3 0 Lentiviral Tat protein RVT_1 PF00078.27 GBG88308.1 - 9.2e-05 22.1 0.1 0.0073 15.8 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5375 PF17345.2 GBG88308.1 - 0.1 12.5 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5375) EF-hand_like PF09279.11 GBG88308.1 - 0.21 12.1 1.2 0.68 10.5 1.2 1.8 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like RT_RNaseH_2 PF17919.1 GBG88309.1 - 1.3e-31 108.5 0.0 3.7e-31 107.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88309.1 - 4.9e-27 94.3 0.0 1.3e-26 92.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88309.1 - 0.00046 19.8 0.2 0.00085 18.9 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG88309.1 - 0.31 10.6 0.0 0.31 10.6 0.0 3.4 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Tropomyosin_1 PF12718.7 GBG88311.1 - 0.013 15.6 3.6 0.015 15.4 3.6 1.2 1 0 0 1 1 1 0 Tropomyosin like TMF_DNA_bd PF12329.8 GBG88311.1 - 0.016 15.2 2.8 0.021 14.8 2.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 GBG88311.1 - 0.088 13.4 4.0 0.17 12.5 2.1 2.0 1 1 1 2 2 2 0 SlyX XhlA PF10779.9 GBG88311.1 - 0.092 13.0 1.0 0.13 12.4 1.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA PI3K_1B_p101 PF10486.9 GBG88312.1 - 2.3 5.9 9.0 3.4 5.3 9.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Integrase_H2C2 PF17921.1 GBG88313.1 - 6.2e-13 48.6 0.6 1.4e-12 47.5 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG88313.1 - 5.7e-11 42.7 0.0 1.6e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain AIP3 PF03915.13 GBG88313.1 - 0.00034 19.8 13.5 0.0011 18.2 3.5 2.4 2 0 0 2 2 2 2 Actin interacting protein 3 Retrotrans_gag PF03732.17 GBG88313.1 - 0.012 15.9 0.1 0.012 15.9 0.1 4.3 5 1 0 5 5 5 0 Retrotransposon gag protein Endonuc-FokI_C PF09254.11 GBG88313.1 - 0.18 11.1 0.1 0.46 9.7 0.1 1.6 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal RVT_1 PF00078.27 GBG88314.1 - 5.6e-25 88.2 0.2 8e-25 87.7 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5095 PF17016.5 GBG88314.1 - 0.15 11.7 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) YabA PF06156.13 GBG88315.1 - 0.097 13.3 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA RVT_1 PF00078.27 GBG88316.1 - 8.8e-33 113.7 0.3 2.2e-32 112.4 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88316.1 - 4e-30 103.8 0.0 8.3e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88316.1 - 4.6e-26 91.1 0.0 9.3e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88316.1 - 3e-18 66.1 0.0 7.7e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG88316.1 - 1.6e-11 44.1 0.0 5e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG88316.1 - 0.14 11.9 0.0 0.5 10.2 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain AIG1 PF04548.16 GBG88318.1 - 5.4e-67 225.2 0.1 7.6e-67 224.7 0.1 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GBG88318.1 - 1.7e-06 28.1 0.0 4.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynein_light PF01221.18 GBG88318.1 - 0.083 13.2 0.5 0.2 12.0 0.5 1.7 1 0 0 1 1 1 0 Dynein light chain type 1 ABC_tran PF00005.27 GBG88318.1 - 0.11 13.1 0.3 0.74 10.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter DUF1835 PF08874.10 GBG88318.1 - 0.12 12.6 0.6 0.24 11.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) Erf4 PF10256.9 GBG88318.1 - 0.15 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Dynamin_N PF00350.23 GBG88318.1 - 0.22 11.6 3.5 11 6.1 0.0 2.9 2 1 0 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 GBG88318.1 - 0.23 11.4 3.3 0.17 11.7 0.3 2.3 3 1 0 3 3 3 0 RsgA GTPase RT_RNaseH_2 PF17919.1 GBG88319.1 - 3.7e-31 107.1 0.0 6.8e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88319.1 - 6.4e-30 103.5 0.1 1.4e-29 102.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG88319.1 - 0.0079 15.8 3.2 0.049 13.3 0.0 2.3 2 0 0 2 2 2 1 Phage capsid scaffolding protein (GPO) serine peptidase DUF659 PF04937.15 GBG88320.1 - 5.9e-28 97.6 0.1 8.9e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88320.1 - 4e-05 23.3 0.2 7.5e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UvrD-helicase PF00580.21 GBG88321.1 - 1.1e-29 103.9 0.0 1.5e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 GBG88321.1 - 4e-15 56.4 0.3 7e-15 55.6 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG88321.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG88321.1 - 0.0042 16.8 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Na_Ca_ex PF01699.24 GBG88322.1 - 2.5e-34 118.4 33.0 2.5e-17 63.2 7.9 2.9 2 1 1 3 3 3 2 Sodium/calcium exchanger protein NADH_dh_m_C1 PF15088.6 GBG88322.1 - 0.22 11.2 0.3 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DUF2627 PF11118.8 GBG88322.1 - 0.22 12.1 6.4 1.1 9.9 0.2 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) MFS_MOT1 PF16983.5 GBG88322.1 - 0.28 11.6 14.3 0.42 11.0 2.6 3.1 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily EF-hand_4 PF12763.7 GBG88324.1 - 5.4e-17 61.7 0.0 3.1e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 GBG88324.1 - 1.1e-09 37.1 0.0 0.00082 18.7 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 GBG88324.1 - 6.9e-08 32.8 0.0 0.00035 21.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG88324.1 - 3.1e-06 26.7 0.0 0.092 12.7 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 GBG88324.1 - 0.00039 20.2 0.0 1.3 8.9 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 GBG88324.1 - 0.0052 16.2 0.0 0.052 13.1 0.1 2.2 2 0 0 2 2 2 1 EF hand Exonuc_VII_L PF02601.15 GBG88324.1 - 1.7 8.2 6.6 2.7 7.5 6.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Histone PF00125.24 GBG88325.1 - 2.2e-27 96.0 0.6 1.8e-20 73.6 0.0 2.7 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 BCAS2 PF05700.11 GBG88326.1 - 5.6e-64 215.6 5.8 9.2e-64 214.9 5.8 1.4 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Haspin_kinase PF12330.8 GBG88326.1 - 4.7e-41 140.9 0.0 8.2e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Cnn_1N PF07989.11 GBG88326.1 - 0.15 12.3 5.8 1.8 8.8 5.8 2.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 5_nucleotid PF05761.14 GBG88326.1 - 2.2 7.1 3.8 4.7 6.0 3.8 1.4 1 0 0 1 1 1 0 5' nucleotidase family FUSC PF04632.12 GBG88326.1 - 3.3 6.1 5.1 5.2 5.5 5.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phosphorylase PF00343.20 GBG88327.1 - 1.3e-290 965.8 0.0 1.6e-290 965.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase MutL_C PF08676.11 GBG88328.1 - 3.6e-29 101.4 0.1 1.3e-25 89.9 0.0 2.6 2 0 0 2 2 2 2 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 GBG88328.1 - 1.4e-24 86.0 0.0 4.6e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GBG88328.1 - 1.9e-08 34.2 0.0 1.9e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GBG88328.1 - 0.00048 20.6 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.32 GBG88330.1 - 9.3e-17 61.1 6.4 5.7e-05 23.8 0.1 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat F-box-like PF12937.7 GBG88330.1 - 7.2e-09 35.4 0.9 1.6e-08 34.3 0.9 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 GBG88330.1 - 9.3e-09 35.5 0.0 0.047 14.0 0.0 4.7 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GBG88330.1 - 0.00011 22.0 0.1 0.00022 21.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 GBG88330.1 - 0.00013 21.7 0.1 0.00081 19.0 0.1 2.2 1 1 0 1 1 1 1 PQQ-like domain Frtz PF11768.8 GBG88330.1 - 0.077 11.3 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 GBG88331.1 - 2.2e-15 56.8 11.6 0.00083 20.1 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat F-box-like PF12937.7 GBG88331.1 - 7.7e-09 35.3 0.9 1.8e-08 34.2 0.9 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 GBG88331.1 - 1.5e-08 34.8 0.0 0.054 13.8 0.0 4.6 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GBG88331.1 - 9.3e-05 22.2 0.1 0.00024 20.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 GBG88331.1 - 0.00016 21.3 0.1 0.0009 18.9 0.1 2.1 1 1 0 1 1 1 1 PQQ-like domain Frtz PF11768.8 GBG88331.1 - 0.088 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz FAD_binding_2 PF00890.24 GBG88332.1 - 3.8e-31 108.6 0.0 5e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GBG88332.1 - 2.6e-24 86.0 0.1 6.4e-24 84.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GBG88332.1 - 1e-16 61.1 0.0 1.7e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GBG88332.1 - 0.0015 18.7 0.1 0.029 14.5 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Chordopox_A33R PF05966.12 GBG88332.1 - 0.25 10.6 0.0 1.2 8.4 0.0 1.9 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Pkinase PF00069.25 GBG88335.1 - 2.5e-20 73.0 0.0 1.7e-18 66.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG88335.1 - 1.7e-07 30.4 0.0 8.5e-07 28.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 GBG88335.1 - 2.7e-07 30.1 0.0 5.1e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 GBG88335.1 - 0.041 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GBG88335.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CDC27 PF09507.10 GBG88335.1 - 2.8 7.2 15.9 5 6.4 15.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pkinase PF00069.25 GBG88336.1 - 1.7e-18 66.9 0.0 2.6e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG88336.1 - 3.9e-07 29.2 0.0 5.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 GBG88336.1 - 9.3e-07 28.4 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GBG88336.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GBG88336.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GBG88336.1 - 0.26 11.1 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family CDC27 PF09507.10 GBG88336.1 - 1.8 7.9 15.9 3.1 7.1 15.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RIBIOP_C PF04950.12 GBG88337.1 - 3.2e-112 374.7 0.0 5.9e-112 373.8 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GBG88337.1 - 3.3e-22 78.4 0.0 7.8e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain V-ATPase_G PF03179.15 GBG88338.1 - 4.4e-16 59.3 0.6 1.1e-10 41.9 0.7 2.1 2 0 0 2 2 2 2 Vacuolar (H+)-ATPase G subunit YL1 PF05764.13 GBG88338.1 - 0.052 13.7 9.2 0.068 13.3 9.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GBG88338.1 - 0.068 12.6 11.8 0.087 12.2 11.8 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GBG88338.1 - 1.4 7.9 16.8 1.7 7.7 16.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GBG88338.1 - 8.3 4.4 23.0 11 4.0 23.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GBG88339.1 - 1.2 8.4 16.9 0.016 14.5 5.5 2.2 2 0 0 2 2 2 0 NOA36 protein DUF659 PF04937.15 GBG88340.1 - 1.6e-09 37.8 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG88341.1 - 1.4e-13 51.1 0.2 3.1e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG88341.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) Rieske PF00355.26 GBG88342.1 - 7.9e-19 67.4 0.0 2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG88342.1 - 2.6e-18 65.9 0.0 4.6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Pheophorbide a oxygenase DUF4407 PF14362.6 GBG88342.1 - 0.041 13.2 0.5 0.068 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 GBG88342.1 - 0.089 12.8 1.6 0.15 12.1 1.6 1.3 1 0 0 1 1 1 0 Laminin Domain II NOA36 PF06524.12 GBG88342.1 - 0.63 9.3 5.9 0.98 8.7 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 GBG88342.1 - 0.75 9.6 5.3 1.5 8.7 5.3 1.4 1 0 0 1 1 1 0 Myc amino-terminal region MukE PF04288.13 GBG88342.1 - 2.3 7.1 5.4 3.4 6.5 5.4 1.2 1 0 0 1 1 1 0 MukE-like family RT_RNaseH_2 PF17919.1 GBG88343.1 - 1.6e-29 101.9 0.0 2.9e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88343.1 - 1.7e-27 95.7 0.0 3.1e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88343.1 - 7.5e-06 25.6 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG88343.1 - 0.033 14.1 0.0 0.67 9.9 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Cwf_Cwc_15 PF04889.12 GBG88343.1 - 0.15 11.8 23.9 0.22 11.2 23.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG88343.1 - 0.48 9.8 29.2 0.7 9.3 29.2 1.1 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG88343.1 - 0.57 10.4 15.3 1.1 9.5 15.3 1.6 1 1 0 1 1 1 0 Sodium ion transport-associated Nop53 PF07767.11 GBG88343.1 - 1.3 8.3 27.3 1.9 7.8 27.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GBG88343.1 - 3.3 5.9 21.5 4.9 5.3 21.5 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG88343.1 - 7.6 5.8 30.5 12 5.1 30.5 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG88343.1 - 8.6 4.4 30.5 12 3.9 30.5 1.1 1 0 0 1 1 1 0 Nop14-like family HSP70 PF00012.20 GBG88343.1 - 10 4.2 18.3 14 3.7 18.3 1.1 1 0 0 1 1 1 0 Hsp70 protein RT_RNaseH_2 PF17919.1 GBG88344.1 - 6.7e-27 93.5 0.0 1.1e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88344.1 - 1.7e-24 86.1 0.0 2.9e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG88344.1 - 0.23 9.6 10.5 0.29 9.3 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG88344.1 - 2 7.8 12.1 2.7 7.3 12.1 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG88344.1 - 7.1 4.8 10.2 9.7 4.3 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2 PF00096.26 GBG88345.1 - 9.1e-07 29.0 27.3 0.017 15.5 1.3 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GBG88345.1 - 2.2e-05 24.6 13.1 0.0034 17.7 3.2 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 GBG88345.1 - 2.7e-05 24.4 6.8 0.012 15.9 0.3 3.0 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 GBG88345.1 - 0.014 16.1 1.3 0.014 16.1 1.3 5.4 6 0 0 6 6 6 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 GBG88345.1 - 0.086 12.8 9.7 0.73 9.9 5.9 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.13 GBG88345.1 - 0.21 11.7 3.8 0.58 10.2 3.8 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.6 GBG88345.1 - 2 8.5 22.6 0.32 11.0 1.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GBG88345.1 - 5.7 7.0 9.0 3.9 7.5 1.1 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF659 PF04937.15 GBG88346.1 - 3.7e-14 52.8 0.0 5.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF1664 PF07889.12 GBG88347.1 - 0.14 12.2 6.0 0.28 11.2 3.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 GBG88347.1 - 1.7 6.0 23.4 2.2 5.7 23.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fzo_mitofusin PF04799.13 GBG88347.1 - 1.7 8.1 7.4 2 7.9 1.9 2.6 3 0 0 3 3 3 0 fzo-like conserved region Phage_Gp23 PF10669.9 GBG88347.1 - 3.4 8.0 17.8 0.81 10.0 14.5 1.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) FAM76 PF16046.5 GBG88347.1 - 8.1 5.7 14.8 12 5.1 14.8 1.2 1 0 0 1 1 1 0 FAM76 protein zf-CCHC PF00098.23 GBG88348.1 - 0.087 12.9 0.9 0.15 12.2 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DNA_pack_N PF02500.15 GBG88349.1 - 0.0019 18.1 2.7 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 1 Probable DNA packing protein, N-terminus DUF4286 PF14114.6 GBG88349.1 - 0.017 15.6 1.9 3.9 8.0 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) VPS13_mid_rpt PF16910.5 GBG88350.1 - 8.3e-41 140.0 0.5 3.6e-21 75.7 0.0 3.3 4 0 0 4 4 4 2 Repeating coiled region of VPS13 Retrotrans_gag PF03732.17 GBG88350.1 - 0.06 13.6 0.8 4.3 7.7 0.1 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein SHR-BD PF06650.12 GBG88351.1 - 1.3e-40 139.5 0.0 3.8e-22 79.0 0.0 5.3 5 0 0 5 5 5 5 SHR-binding domain of vacuolar-sorting associated protein 13 DUF1923 PF09083.10 GBG88352.1 - 0.91 9.3 4.9 0.35 10.6 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) VPS13_C PF16909.5 GBG88353.1 - 1.8e-35 122.3 0.0 5.2e-35 120.8 0.0 1.8 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Apt1 PF10351.9 GBG88353.1 - 0.032 13.1 0.0 0.032 13.1 0.0 2.6 3 0 0 3 3 3 0 Golgi-body localisation protein domain ATG_C PF09333.11 GBG88353.1 - 0.28 11.5 2.2 0.4 11.1 0.2 2.3 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain E3_UbLigase_R4 PF13764.6 GBG88353.1 - 2.4 6.2 7.4 3.6 5.6 7.4 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 K_channel_TID PF07941.11 GBG88353.1 - 4.1 7.9 10.5 15 6.1 10.5 2.0 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Hamartin PF04388.12 GBG88354.1 - 0.5 9.0 14.0 0.57 8.8 14.0 1.0 1 0 0 1 1 1 0 Hamartin protein Put_Phosphatase PF06888.12 GBG88355.1 - 5.3e-67 225.6 0.0 6.2e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 GBG88355.1 - 3.8e-05 24.2 0.1 0.00011 22.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Yqai PF09466.10 GBG88355.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein Yqai PAP2_C PF14360.6 GBG88356.1 - 2.6e-20 72.7 5.6 2.6e-20 72.7 5.6 2.1 2 0 0 2 2 2 1 PAP2 superfamily C-terminal TPR_2 PF07719.17 GBG88356.1 - 3.6e-05 23.6 0.1 0.23 11.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG88356.1 - 0.00091 19.0 0.1 2.9 7.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat PAP2_3 PF14378.6 GBG88356.1 - 0.0015 18.2 14.2 0.0044 16.7 14.2 1.8 1 1 0 1 1 1 1 PAP2 superfamily DUF4810 PF16068.5 GBG88356.1 - 0.016 15.8 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) DUF3980 PF13140.6 GBG88356.1 - 0.017 15.5 0.3 0.05 14.1 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) HTH_Tnp_IS1 PF12759.7 GBG88356.1 - 0.074 12.7 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 InsA C-terminal domain PAP2 PF01569.21 GBG88356.1 - 2.1 8.1 8.4 1.2 8.9 6.1 1.8 1 1 0 1 1 1 0 PAP2 superfamily DDE_Tnp_4 PF13359.6 GBG88359.1 - 1e-11 44.8 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88359.1 - 3.5e-05 23.5 0.0 5.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Astro_capsid_p PF12226.8 GBG88361.1 - 0.077 12.1 11.1 0.12 11.5 11.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2457 PF10446.9 GBG88361.1 - 0.35 10.0 13.5 0.59 9.2 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 GBG88361.1 - 1.1 7.7 6.1 1.6 7.2 6.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pes-10 PF07149.11 GBG88361.1 - 9.7 5.1 13.7 18 4.2 13.7 1.4 1 0 0 1 1 1 0 Pes-10 RT_RNaseH PF17917.1 GBG88362.1 - 5.4e-25 87.7 0.0 1.3e-24 86.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88362.1 - 3.6e-24 84.7 0.0 6.2e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88362.1 - 5.7e-20 71.2 0.2 1.1e-19 70.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88362.1 - 8.5e-08 32.4 0.0 2.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG88362.1 - 0.0079 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG88363.1 - 6.9e-24 83.8 0.1 2.3e-23 82.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88363.1 - 1.4e-21 76.8 0.0 3.3e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sigma54_CBD PF04963.13 GBG88365.1 - 0.052 13.4 1.0 0.29 11.0 0.3 2.4 3 0 0 3 3 3 0 Sigma-54 factor, core binding domain Retrotrans_gag PF03732.17 GBG88365.1 - 0.79 10.0 8.5 1.3 9.3 0.1 3.7 5 1 0 5 5 5 0 Retrotransposon gag protein TFIIA PF03153.13 GBG88365.1 - 3.7 7.4 21.0 6.2 6.7 21.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH_2 PF17919.1 GBG88366.1 - 1.9e-33 114.5 0.1 3.1e-33 113.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88366.1 - 8.9e-31 107.1 0.1 1.4e-30 106.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88366.1 - 2.8e-29 101.5 0.1 4.9e-29 100.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5095 PF17016.5 GBG88366.1 - 0.14 11.8 0.7 0.21 11.3 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) FtsK_SpoIIIE PF01580.18 GBG88367.1 - 1 8.7 4.1 1.1 8.6 2.8 1.5 1 1 1 2 2 2 0 FtsK/SpoIIIE family PPL5 PF18168.1 GBG88367.1 - 1.2 8.4 7.6 1.3 8.3 7.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 SURF2 PF05477.11 GBG88367.1 - 1.7 8.3 14.1 1.9 8.1 14.0 1.3 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PA26 PF04636.13 GBG88367.1 - 1.9 7.3 8.3 2.2 7.1 8.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF913 PF06025.12 GBG88367.1 - 5.6 5.8 7.0 5.3 5.9 7.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RT_RNaseH_2 PF17919.1 GBG88368.1 - 1e-23 83.2 0.0 2e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88368.1 - 6.1e-21 74.7 0.0 1.1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG88368.1 - 0.00069 20.1 0.0 0.0017 18.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88368.1 - 0.0022 18.6 0.0 0.005 17.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG88368.1 - 0.036 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88368.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Glyco_hydro_43 PF04616.14 GBG88369.1 - 5.7 6.2 5.9 21 4.3 0.1 3.2 2 1 0 2 2 2 0 Glycosyl hydrolases family 43 SeleniumBinding PF11524.8 GBG88369.1 - 7.4 7.1 26.8 8 7.0 0.1 8.4 1 1 10 11 11 11 0 Selenium binding protein RT_RNaseH_2 PF17919.1 GBG88370.1 - 3.3e-22 78.4 0.0 5.6e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88370.1 - 4.4e-20 71.9 0.0 9.6e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88370.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG88371.1 - 1.1e-21 77.3 0.1 2e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG88371.1 - 1.8e-09 37.8 0.0 4.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG88371.1 - 1.7e-07 31.8 0.0 4.3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88371.1 - 9.3e-06 26.1 0.0 2.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG88371.1 - 0.00062 19.6 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG88371.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88371.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG88372.1 - 5.5e-05 23.4 6.7 0.049 13.9 0.1 3.8 3 0 0 3 3 3 2 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG88372.1 - 0.0053 17.4 3.6 0.0053 17.4 3.6 3.6 3 1 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 SNAPc19 PF15497.6 GBG88372.1 - 0.33 11.5 7.4 0.61 10.6 0.0 3.1 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Fzo_mitofusin PF04799.13 GBG88372.1 - 0.35 10.4 6.6 7.6 6.1 0.1 2.4 2 0 0 2 2 2 0 fzo-like conserved region Spc24 PF08286.11 GBG88372.1 - 0.7 10.2 8.9 5 7.4 0.5 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Baculo_PEP_C PF04513.12 GBG88372.1 - 0.93 9.5 4.9 4.7 7.2 4.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad3 PF08656.10 GBG88372.1 - 0.99 9.5 5.2 26 5.0 0.1 2.8 2 1 0 2 2 2 0 DASH complex subunit Dad3 LMBR1 PF04791.16 GBG88372.1 - 1.1 8.1 4.4 1.5 7.6 4.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein FliD_N PF02465.18 GBG88372.1 - 4.8 7.9 8.5 3.9 8.2 0.2 3.1 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus M PF02370.16 GBG88372.1 - 5 8.0 10.2 4.5 8.2 4.6 3.4 2 0 0 2 2 2 0 M protein repeat MPP6 PF10175.9 GBG88372.1 - 6.5 7.3 7.6 7.4 7.1 0.5 2.6 2 1 1 3 3 3 0 M-phase phosphoprotein 6 RT_RNaseH_2 PF17919.1 GBG88373.1 - 9.2e-24 83.4 0.0 1.2e-22 79.8 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88373.1 - 7e-21 74.5 0.0 7e-20 71.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88373.1 - 6.6e-16 58.6 0.0 1.8e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG88373.1 - 6.2e-10 39.0 0.0 2e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG88373.1 - 0.005 16.6 0.0 0.027 14.2 0.0 2.3 1 1 1 2 2 2 1 Integrase core domain ACT_3 PF10000.9 GBG88373.1 - 0.17 11.8 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 ACT domain Retrotrans_gag PF03732.17 GBG88373.1 - 0.22 11.8 1.2 1.1 9.5 0.4 2.5 1 1 1 2 2 2 0 Retrotransposon gag protein Dynactin_p62 PF05502.13 GBG88374.1 - 0.056 12.2 2.2 0.096 11.4 2.2 1.3 1 0 0 1 1 1 0 Dynactin p62 family Presenilin PF01080.17 GBG88374.1 - 0.53 9.0 1.3 0.83 8.3 1.3 1.2 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 GBG88374.1 - 1.4 7.3 4.5 2.2 6.7 4.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rap1_C PF11626.8 GBG88374.1 - 4.8 7.3 7.3 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HABP4_PAI-RBP1 PF04774.15 GBG88375.1 - 3.2 8.6 36.2 3.5 8.5 36.2 1.0 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Spore_coat_CotO PF14153.6 GBG88375.1 - 5.7 6.8 27.5 5.4 6.9 27.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FAM60A PF15396.6 GBG88375.1 - 6 6.8 7.2 6 6.8 7.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Toprim_N PF08275.11 GBG88377.1 - 1.4e-07 31.6 0.4 12 5.9 0.0 6.9 2 2 6 8 8 8 3 DNA primase catalytic core, N-terminal domain RTA1 PF04479.13 GBG88377.1 - 1.3e-05 25.0 7.6 13 5.3 0.0 7.7 4 3 6 10 10 10 1 RTA1 like protein ORF_2_N PF18492.1 GBG88377.1 - 0.0014 18.9 0.0 37 4.5 0.0 5.1 4 1 1 6 6 6 0 Open reading frame 2 N-terminal domain PapC_C PF13953.6 GBG88377.1 - 0.0019 18.0 25.6 13 5.7 0.1 8.6 2 1 8 10 10 10 2 PapC C-terminal domain FBA_3 PF08268.12 GBG88377.1 - 0.0093 15.9 21.7 6.4 6.7 0.2 5.6 1 1 5 6 6 6 4 F-box associated domain DdrB PF12747.7 GBG88377.1 - 0.0098 15.7 18.4 7.8 6.3 0.3 6.3 1 1 3 5 5 5 4 DdrB-like protein SH3_19 PF18597.1 GBG88377.1 - 0.043 13.7 45.9 12 5.8 0.1 11.4 13 0 0 13 13 13 0 Myosin X N-terminal SH3 domain Pirin_C PF05726.13 GBG88377.1 - 2.7 8.4 6.5 85 3.6 0.3 4.2 2 2 2 4 4 4 0 Pirin C-terminal cupin domain RVT_1 PF00078.27 GBG88378.1 - 4.6e-30 104.8 0.0 6.4e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG88378.1 - 0.023 13.8 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 FAM76 PF16046.5 GBG88379.1 - 0.0031 16.9 8.4 0.012 15.0 9.0 1.6 2 0 0 2 2 2 1 FAM76 protein Retrotrans_gag PF03732.17 GBG88379.1 - 0.012 15.9 5.3 0.017 15.4 0.2 3.5 4 0 0 4 4 4 0 Retrotransposon gag protein DUF4187 PF13821.6 GBG88379.1 - 0.036 13.9 2.5 0.044 13.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Baculo_PEP_C PF04513.12 GBG88379.1 - 0.12 12.4 6.7 0.11 12.5 4.5 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_32 PF13679.6 GBG88379.1 - 0.99 9.4 4.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain PspB PF06667.12 GBG88379.1 - 1.1 9.3 11.0 15 5.7 0.2 3.1 3 0 0 3 3 3 0 Phage shock protein B APG6_N PF17675.1 GBG88379.1 - 1.2 9.7 22.7 0.38 11.3 0.9 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region MRP-S26 PF14943.6 GBG88379.1 - 2 8.3 14.0 9.7 6.1 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosome subunit S26 RT_RNaseH_2 PF17919.1 GBG88380.1 - 1e-32 112.1 0.0 1.9e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88380.1 - 1.2e-29 102.6 0.1 2.7e-29 101.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88380.1 - 3.2e-13 49.9 0.1 8e-13 48.6 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG88380.1 - 0.14 11.8 1.0 0.97 9.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) RT_RNaseH_2 PF17919.1 GBG88381.1 - 1.1e-30 105.6 0.0 2.1e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88381.1 - 3.5e-27 95.4 0.0 6.4e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88381.1 - 1.1e-23 83.5 0.0 2.3e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88381.1 - 2.6e-19 69.1 0.1 5.2e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88381.1 - 2.6e-16 59.9 0.1 5.4e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG88381.1 - 0.0025 18.0 0.0 0.0098 16.1 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG88382.1 - 8.7e-29 99.9 0.3 1.2e-27 96.2 0.1 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88382.1 - 6.1e-20 71.1 0.0 5.7e-19 68.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88382.1 - 5.8e-18 64.8 0.5 1.2e-17 63.8 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88382.1 - 3.2e-17 62.8 0.1 1.6e-16 60.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG88382.1 - 0.021 15.1 0.1 0.058 13.6 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG88382.1 - 0.075 13.0 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Casc1_N PF15927.5 GBG88382.1 - 0.14 11.9 12.3 0.34 10.6 12.3 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Phage_GPO PF05929.11 GBG88382.1 - 0.7 9.5 3.9 0.3 10.7 0.1 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase CHD5 PF04420.14 GBG88382.1 - 5.3 6.9 6.0 12 5.7 6.0 1.5 1 0 0 1 1 1 0 CHD5-like protein Integrase_H2C2 PF17921.1 GBG88383.1 - 1.2e-20 73.4 0.3 6.5e-20 71.0 0.2 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG88383.1 - 6.6e-10 39.2 0.0 2e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG88383.1 - 6e-06 26.5 0.5 1.2e-05 25.6 0.5 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG88383.1 - 0.004 17.3 0.0 0.0092 16.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG88383.1 - 0.018 14.9 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FA_desaturase PF00487.24 GBG88383.1 - 0.14 12.0 3.4 0.25 11.2 3.4 1.4 1 0 0 1 1 1 0 Fatty acid desaturase RT_RNaseH_2 PF17919.1 GBG88384.1 - 8.2e-30 102.8 0.0 1.6e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88384.1 - 1.1e-27 96.3 0.0 2e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88384.1 - 5.9e-27 94.6 0.0 1e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88384.1 - 1.3e-11 44.4 0.0 3.8e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1564 PF07600.11 GBG88384.1 - 0.0016 18.2 0.2 0.0099 15.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) CotJB PF12652.7 GBG88384.1 - 0.62 10.3 5.5 6.5 7.0 0.1 3.4 4 0 0 4 4 4 0 CotJB protein Neugrin PF06413.11 GBG88385.1 - 2.6 8.0 12.0 5.7 6.9 12.0 1.6 2 0 0 2 2 2 0 Neugrin BUD22 PF09073.10 GBG88385.1 - 3.3 7.0 30.3 4.6 6.5 30.3 1.1 1 0 0 1 1 1 0 BUD22 Na_trans_assoc PF06512.13 GBG88385.1 - 9.1 6.5 17.5 15 5.8 17.5 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated RT_RNaseH_2 PF17919.1 GBG88386.1 - 6.2e-25 87.2 0.0 1.2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88386.1 - 1e-23 83.6 0.0 1.9e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88386.1 - 1.9e-09 37.4 0.1 2.8e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Neugrin PF06413.11 GBG88386.1 - 7 6.6 11.8 12 5.9 11.8 1.3 1 0 0 1 1 1 0 Neugrin DNA_pol_A_exo1 PF01612.20 GBG88387.1 - 1.9e-15 57.0 0.0 3.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DDE_Tnp_4 PF13359.6 GBG88388.1 - 5e-27 94.5 0.1 3.2e-26 91.9 0.0 2.2 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88388.1 - 1.4e-13 51.0 0.0 2.1e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88388.1 - 0.00043 20.0 0.2 0.0078 15.9 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG88388.1 - 0.029 14.7 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG88389.1 - 9.4e-09 35.5 6.9 1.4e-07 31.8 4.1 2.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG88389.1 - 0.0081 16.4 4.0 0.026 14.8 2.3 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DEAD_2 PF06733.15 GBG88390.1 - 7.2e-51 172.3 0.0 2.2e-50 170.7 0.0 1.8 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 GBG88390.1 - 1.3e-36 126.1 0.0 2.9e-29 102.1 0.0 2.7 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 GBG88390.1 - 8.2e-21 74.9 1.1 6.6e-14 52.4 0.2 2.8 2 1 1 3 3 3 2 Helicase C-terminal domain ResIII PF04851.15 GBG88390.1 - 4.3e-07 30.1 0.1 4.3e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 GBG88390.1 - 0.016 14.0 0.1 3.4 6.3 0.1 2.4 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA PF00004.29 GBG88390.1 - 0.021 15.3 0.2 3.1 8.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 GBG88390.1 - 0.029 14.2 0.1 0.97 9.2 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.9 GBG88390.1 - 0.086 12.1 0.1 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 GBG88390.1 - 0.11 12.8 0.0 0.49 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AP2 PF00847.20 GBG88391.1 - 4.5e-17 62.0 16.2 5.1e-06 26.6 1.1 4.5 4 0 0 4 4 4 4 AP2 domain BSP_II PF05432.11 GBG88391.1 - 0.029 14.1 26.4 0.15 11.7 12.7 2.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF2052 PF09747.9 GBG88391.1 - 0.28 11.3 29.0 1.7 8.8 13.4 2.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) XAP5 PF04921.14 GBG88392.1 - 1.5e-48 165.8 0.1 2.9e-48 164.9 0.1 1.3 1 0 0 1 1 1 1 XAP5, circadian clock regulator Herpes_BLRF2 PF05812.12 GBG88393.1 - 0.022 14.9 0.3 0.061 13.5 0.3 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Gp-FAR-1 PF05823.12 GBG88393.1 - 0.053 13.9 2.7 0.084 13.2 2.7 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF5094 PF17015.5 GBG88393.1 - 0.066 13.3 0.9 0.12 12.5 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) YabA PF06156.13 GBG88393.1 - 0.072 13.7 1.7 0.15 12.7 1.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_1 PF00170.21 GBG88393.1 - 0.082 13.0 3.0 0.18 11.9 3.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor GAS PF13851.6 GBG88393.1 - 0.13 11.6 3.7 0.2 11.0 3.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 GBG88393.1 - 0.15 12.3 3.8 0.23 11.6 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.15 GBG88393.1 - 0.19 11.8 5.2 0.35 11.0 5.2 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Laminin_I PF06008.14 GBG88393.1 - 0.21 11.3 2.6 0.31 10.7 2.6 1.1 1 0 0 1 1 1 0 Laminin Domain I Tom22 PF04281.13 GBG88393.1 - 2.9 7.7 7.1 5.4 6.8 7.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 RT_RNaseH_2 PF17919.1 GBG88394.1 - 4.5e-26 90.8 0.0 1.1e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88394.1 - 2.6e-20 72.7 0.0 5.3e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88394.1 - 1.2e-10 41.3 0.0 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG88394.1 - 0.00019 21.6 2.5 0.0018 18.5 0.2 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein APG17 PF04108.12 GBG88394.1 - 0.0094 15.1 0.1 0.037 13.1 0.0 2.0 2 0 0 2 2 2 1 Autophagy protein Apg17 gag-asp_proteas PF13975.6 GBG88395.1 - 0.0002 21.9 0.3 0.00078 20.0 0.1 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88395.1 - 0.0019 18.8 0.1 0.0059 17.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF1048 PF06304.11 GBG88395.1 - 0.0031 17.9 0.2 0.0083 16.6 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1048) Retrotrans_gag PF03732.17 GBG88395.1 - 0.011 16.0 0.1 0.088 13.1 0.0 2.4 2 1 0 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 GBG88395.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease FAM176 PF14851.6 GBG88395.1 - 4.1 7.1 13.1 9.4 5.9 2.7 3.2 3 0 0 3 3 3 0 FAM176 family DUF4187 PF13821.6 GBG88396.1 - 0.13 12.1 4.9 0.062 13.1 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) DDE_Tnp_4 PF13359.6 GBG88397.1 - 6.9e-23 81.1 0.0 1.4e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88397.1 - 1.2e-08 34.8 0.0 2.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88397.1 - 0.09 12.4 11.9 0.13 11.9 0.0 3.4 3 1 0 4 4 4 0 Transposase DDE domain Herpes_UL25 PF01499.16 GBG88397.1 - 7 5.0 7.5 12 4.2 7.5 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family PP2 PF14299.6 GBG88398.1 - 7.3e-20 71.5 0.0 1.1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Phloem protein 2 F-box PF00646.33 GBG88398.1 - 8.8e-07 28.7 0.1 1.9e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG88398.1 - 5.4e-05 23.0 0.4 0.00013 21.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like DUF3446 PF11928.8 GBG88398.1 - 0.15 12.4 13.7 0.31 11.4 13.7 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain PP2 PF14299.6 GBG88399.1 - 2.1e-21 76.5 0.0 3.2e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Phloem protein 2 F-box PF00646.33 GBG88399.1 - 3e-07 30.2 0.2 6.4e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG88399.1 - 4.2e-05 23.3 0.7 4.2e-05 23.3 0.7 1.8 2 0 0 2 2 2 1 F-box-like PP2 PF14299.6 GBG88401.1 - 6.6e-09 36.0 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Phloem protein 2 F-box PF00646.33 GBG88401.1 - 8.3e-07 28.7 0.3 8.3e-07 28.7 0.3 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GBG88401.1 - 3.1e-05 23.8 0.7 7.4e-05 22.6 0.7 1.7 1 0 0 1 1 1 1 F-box-like Herpes_pp85 PF04637.12 GBG88401.1 - 4 5.8 5.1 5.6 5.3 5.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Glycos_transf_2 PF00535.26 GBG88402.1 - 2.5e-27 95.8 0.0 2.9e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG88402.1 - 1.4e-16 61.1 0.0 1.4e-15 57.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GBG88402.1 - 1.6e-12 47.5 0.0 2.8e-08 33.6 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 GBG88402.1 - 0.00068 20.1 0.0 0.0018 18.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 GNT-I PF03071.15 GBG88402.1 - 0.066 12.0 0.0 0.12 11.1 0.0 1.4 2 0 0 2 2 2 0 GNT-I family RVT_1 PF00078.27 GBG88403.1 - 2.4e-24 86.1 0.0 4e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG88403.1 - 1.7e-07 31.8 0.0 7.3e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88403.1 - 9.7e-07 29.3 0.0 3.8e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88403.1 - 4.2e-05 23.3 0.0 9.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88403.1 - 5.8e-05 22.9 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG88403.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG88403.1 - 0.057 13.7 0.1 0.72 10.2 0.0 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein CTP_transf_1 PF01148.20 GBG88404.1 - 2.8e-82 276.5 22.2 4.1e-82 275.9 22.2 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family RVT_1 PF00078.27 GBG88404.1 - 1.5e-28 99.8 0.0 2.7e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88404.1 - 2.4e-17 62.8 0.0 9.5e-17 60.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88404.1 - 2.9e-10 40.4 0.0 7.8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG88404.1 - 1.9e-07 31.3 0.0 6.1e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG88404.1 - 4.8e-06 27.1 0.0 1.1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88404.1 - 1.3e-05 25.6 0.0 3.6e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88404.1 - 6.3e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88404.1 - 0.00047 19.9 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG88404.1 - 0.05 13.7 0.4 0.17 12.0 0.4 2.0 1 0 0 1 1 1 0 Integrase zinc binding domain Na_trans_assoc PF06512.13 GBG88404.1 - 0.056 13.7 6.5 0.41 10.9 0.7 2.5 2 0 0 2 2 2 0 Sodium ion transport-associated F-box PF00646.33 GBG88404.1 - 1.6 8.7 4.5 0.33 10.9 0.2 2.1 3 0 0 3 3 3 0 F-box domain ABC_tran PF00005.27 GBG88405.1 - 3.8e-22 79.3 0.9 7.8e-11 42.6 1.9 3.6 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GBG88405.1 - 1.3e-07 31.3 0.0 0.0005 19.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GBG88405.1 - 1.1e-05 25.5 0.1 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GBG88405.1 - 0.00045 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 GBG88405.1 - 0.0016 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GBG88405.1 - 0.023 14.6 1.8 0.81 9.6 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 GBG88405.1 - 0.036 14.6 0.9 1.4 9.5 0.0 3.8 5 1 1 6 6 5 0 AAA domain AAA_23 PF13476.6 GBG88405.1 - 0.059 13.9 0.0 0.059 13.9 0.0 2.7 2 1 0 2 2 1 0 AAA domain AAA_22 PF13401.6 GBG88405.1 - 0.13 12.6 1.4 0.33 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain CsgE PF10627.9 GBG88405.1 - 3.5 7.9 5.4 10 6.4 5.4 1.8 1 0 0 1 1 1 0 Curli assembly protein CsgE AAA_16 PF13191.6 GBG88405.1 - 8.2 6.8 15.6 57 4.0 12.6 3.2 2 1 0 2 2 2 0 AAA ATPase domain DUF3504 PF12012.8 GBG88406.1 - 3e-06 27.3 0.5 7.2e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) YL1 PF05764.13 GBG88406.1 - 8.8e-05 22.7 11.8 8.8e-05 22.7 11.8 2.6 2 0 0 2 2 2 1 YL1 nuclear protein DUF2457 PF10446.9 GBG88406.1 - 0.00027 20.2 28.5 0.0009 18.5 28.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Roughex PF06020.11 GBG88406.1 - 3.4 6.7 20.3 7.9 5.5 20.3 1.5 1 0 0 1 1 1 0 Drosophila roughex protein RT_RNaseH_2 PF17919.1 GBG88407.1 - 1.8e-26 92.1 0.0 3.4e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88407.1 - 2.1e-25 89.0 0.0 3.6e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88407.1 - 1.5e-12 47.5 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG88407.1 - 0.7 10.1 11.6 1.1 9.4 11.6 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG88407.1 - 3.6 5.7 17.7 4.9 5.3 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG88407.1 - 5.9 6.2 21.5 8.8 5.6 21.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG88407.1 - 8.3 5.6 18.9 12 5.2 18.9 1.1 1 0 0 1 1 1 0 BUD22 JAB PF01398.21 GBG88408.1 - 2.9e-33 114.3 0.3 5.2e-33 113.5 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GBG88408.1 - 1e-13 51.7 0.5 2.1e-13 50.7 0.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 GBG88408.1 - 5.3e-06 26.2 0.0 9.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Mito_carr PF00153.27 GBG88409.1 - 5.5e-69 228.2 2.0 2.8e-24 84.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2457 PF10446.9 GBG88410.1 - 0.19 10.9 30.2 0.18 10.9 30.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GBG88410.1 - 0.79 7.8 32.2 0.88 7.6 32.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 GBG88410.1 - 1.2 8.8 10.5 1.3 8.7 10.5 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop14 PF04147.12 GBG88410.1 - 2.9 6.0 24.9 2.9 6.0 24.9 1.0 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 GBG88410.1 - 6.9 6.5 13.7 7.5 6.3 13.7 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term NPR3 PF03666.13 GBG88410.1 - 9 5.0 8.8 10 4.8 8.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PPP4R2 PF09184.11 GBG88410.1 - 9.4 5.7 19.7 10 5.6 19.7 1.1 1 0 0 1 1 1 0 PPP4R2 Integrase_H2C2 PF17921.1 GBG88413.1 - 2e-09 37.4 0.0 4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88413.1 - 2.4e-07 30.9 0.0 5.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Peptidase_M50 PF02163.22 GBG88416.1 - 0.0024 17.2 0.2 0.0043 16.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M50 Zn_Tnp_IS91 PF14319.6 GBG88417.1 - 0.2 11.7 0.3 1.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain Anti-TRAP PF15777.5 GBG88417.1 - 0.22 11.5 2.0 0.51 10.3 0.7 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein PPR PF01535.20 GBG88418.1 - 3e-37 124.3 22.1 0.00086 19.4 0.1 14.5 14 0 0 14 14 14 8 PPR repeat PPR_2 PF13041.6 GBG88418.1 - 5.7e-37 125.7 2.2 9.6e-08 32.1 0.0 11.5 7 4 5 12 12 12 6 PPR repeat family PPR_3 PF13812.6 GBG88418.1 - 3.2e-35 120.0 0.0 1.3e-08 34.8 0.0 8.7 7 3 2 9 9 9 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG88418.1 - 2.5e-20 71.8 0.3 0.0017 18.0 0.0 8.7 9 0 0 9 9 9 4 PPR repeat PPR_long PF17177.4 GBG88418.1 - 2.8e-15 56.3 0.0 2.4e-10 40.1 0.0 4.5 3 2 2 5 5 5 2 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 GBG88418.1 - 0.00019 21.2 0.0 49 4.3 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG88418.1 - 0.00067 20.3 5.8 12 7.0 0.0 7.3 6 2 2 8 8 8 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GBG88418.1 - 0.031 14.2 0.6 2 8.3 0.0 2.7 2 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal MRP-S27 PF10037.9 GBG88418.1 - 0.35 9.7 2.6 11 4.7 0.0 3.1 3 1 1 4 4 4 0 Mitochondrial 28S ribosomal protein S27 CLIP1_ZNF PF16641.5 GBG88419.1 - 0.11 12.4 1.1 0.2 11.6 1.1 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle DDE_Tnp_4 PF13359.6 GBG88420.1 - 5.2e-18 65.2 0.0 8.5e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88420.1 - 9.8e-13 48.2 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein RPA43_OB PF17875.1 GBG88420.1 - 0.012 16.2 4.2 0.025 15.2 4.2 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I TRM13 PF05206.14 GBG88420.1 - 0.057 12.9 1.0 0.098 12.2 1.0 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 Peptidase_S49_N PF08496.10 GBG88420.1 - 0.11 12.6 2.5 0.2 11.7 2.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 GBG88420.1 - 0.27 11.0 1.1 0.46 10.2 1.1 1.3 1 0 0 1 1 1 0 Connexin Myb_DNA-bind_4 PF13837.6 GBG88421.1 - 8.4e-08 32.5 2.4 1.6e-07 31.6 2.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Ras PF00071.22 GBG88422.1 - 5.9e-59 198.3 0.1 6.8e-59 198.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG88422.1 - 3.5e-34 117.6 0.0 8.2e-34 116.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG88422.1 - 5.4e-11 42.3 0.0 6.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GBG88422.1 - 1.2e-05 25.2 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GBG88422.1 - 0.0018 17.7 0.0 0.0021 17.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GBG88422.1 - 0.0028 17.7 0.0 0.0049 17.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GBG88422.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ATPase PF06745.13 GBG88422.1 - 0.035 13.5 0.1 2.3 7.5 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 GBG88422.1 - 0.052 13.0 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 GBG88422.1 - 0.054 13.9 0.1 0.1 13.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 GBG88422.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Presenilin PF01080.17 GBG88423.1 - 1.7 7.3 6.7 1.5 7.5 6.7 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 GBG88423.1 - 4.3 6.0 7.2 3.4 6.3 7.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 V_ATPase_I PF01496.19 GBG88423.1 - 5.4 4.8 6.1 4.5 5.1 6.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family polyprenyl_synt PF00348.17 GBG88424.1 - 9.2e-66 221.5 0.0 1.9e-65 220.4 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 GBG88424.1 - 6.7e-05 22.6 0.1 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 EF_TS PF00889.19 GBG88425.1 - 9.7e-56 188.7 21.1 1.2e-28 100.2 1.5 5.7 3 2 0 3 3 3 2 Elongation factor TS S1 PF00575.23 GBG88425.1 - 1.3e-20 73.5 2.6 2.6e-18 66.1 0.6 3.2 2 0 0 2 2 2 2 S1 RNA binding domain Ribosomal_L12 PF00542.19 GBG88425.1 - 0.016 15.5 6.1 1.6 9.2 0.2 3.9 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain S1_2 PF13509.6 GBG88425.1 - 0.027 14.6 0.7 0.09 12.8 0.1 2.3 2 1 0 2 2 2 0 S1 domain DPM3 PF08285.11 GBG88425.1 - 0.21 11.8 1.4 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HOIP-UBA PF16678.5 GBG88425.1 - 6.9 6.7 7.7 7.7 6.5 0.8 3.1 4 0 0 4 4 4 0 HOIP UBA domain pair Hydrolase_4 PF12146.8 GBG88426.1 - 1.8e-07 30.7 0.2 0.013 14.8 0.1 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 GBG88426.1 - 1.8e-05 24.8 0.0 2.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 GBG88426.1 - 0.00041 20.1 0.1 0.26 10.9 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GBG88426.1 - 0.0091 15.5 0.2 0.017 14.6 0.2 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 GBG88426.1 - 0.0098 16.0 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.16 GBG88426.1 - 0.013 15.3 0.1 0.76 9.5 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 GBG88426.1 - 0.026 14.2 0.1 0.076 12.7 0.1 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 GBG88426.1 - 0.09 12.3 0.2 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family RHH_3 PF12651.7 GBG88426.1 - 0.097 12.6 0.2 0.62 10.1 0.0 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix domain Rieske PF00355.26 GBG88426.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Abhydrolase_5 PF12695.7 GBG88426.1 - 0.15 11.8 0.2 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Tmemb_14 PF03647.13 GBG88427.1 - 3.3e-15 56.6 8.8 6.5e-15 55.7 8.8 1.5 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3458 PF11940.8 GBG88427.1 - 0.027 14.9 0.3 0.052 14.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold DivIVA PF05103.13 GBG88427.1 - 0.17 11.9 5.5 0.32 11.1 5.5 1.4 1 0 0 1 1 1 0 DivIVA protein Fmp27_GFWDK PF10347.9 GBG88427.1 - 0.28 11.3 2.1 0.76 9.9 1.0 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain YtxH PF12732.7 GBG88427.1 - 2.2 8.9 7.8 1e+02 3.5 7.8 2.5 1 1 0 1 1 1 0 YtxH-like protein Tmemb_14 PF03647.13 GBG88428.1 - 3e-15 56.7 8.8 7.7e-15 55.4 8.8 1.7 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3458 PF11940.8 GBG88428.1 - 0.031 14.7 0.3 0.061 13.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold DivIVA PF05103.13 GBG88428.1 - 0.21 11.7 5.5 0.37 10.9 5.5 1.4 1 0 0 1 1 1 0 DivIVA protein Fmp27_GFWDK PF10347.9 GBG88428.1 - 0.34 11.0 2.1 0.88 9.7 1.0 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain YtxH PF12732.7 GBG88428.1 - 3.2 8.4 7.9 17 6.0 2.1 2.5 1 1 1 2 2 2 0 YtxH-like protein RT_RNaseH_2 PF17919.1 GBG88429.1 - 5.5e-33 113.0 0.1 1.1e-32 112.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88429.1 - 1.1e-31 109.2 0.2 2.4e-31 108.1 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88429.1 - 4.3e-21 75.5 0.1 8.2e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88429.1 - 3.9e-19 68.5 0.0 8.9e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88429.1 - 1.1e-13 51.4 0.1 4.2e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG88429.1 - 0.04 14.1 0.0 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger DUF659 PF04937.15 GBG88430.1 - 3.9e-29 101.5 0.0 5.9e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88430.1 - 0.0045 16.8 0.2 0.0095 15.7 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Beta_helix PF13229.6 GBG88431.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 Right handed beta helix region RVT_1 PF00078.27 GBG88432.1 - 5.2e-35 121.0 0.1 8.3e-35 120.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88432.1 - 1.7e-29 101.8 0.0 4e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88432.1 - 3.7e-29 101.1 0.2 1e-28 99.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG88432.1 - 4.3e-07 29.8 0.0 8.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88432.1 - 1.4e-05 25.6 0.0 3.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG88432.1 - 0.00011 22.2 0.1 0.00038 20.5 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG88432.1 - 0.0013 19.3 0.0 0.004 17.7 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG88432.1 - 0.0016 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Rhamno_transf PF11316.8 GBG88432.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase Asp_protease PF09668.10 GBG88432.1 - 0.067 13.0 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease zf-CCHC_5 PF14787.6 GBG88433.1 - 0.02 14.6 0.3 0.047 13.4 0.3 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SNF2_N PF00176.23 GBG88434.1 - 2.9e-38 131.5 0.0 5.1e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 GBG88434.1 - 2.9e-13 49.5 0.1 6.2e-11 42.0 0.1 2.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 GBG88434.1 - 1.8e-11 44.4 0.0 3.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG88434.1 - 2.2e-07 31.0 0.0 5.6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sec66 PF09802.9 GBG88434.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 HDA2-3 PF11496.8 GBG88434.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 GBG88434.1 - 0.24 11.7 1.0 0.83 9.9 0.2 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pkinase_Tyr PF07714.17 GBG88437.1 - 3.2e-38 131.5 0.0 1.1e-37 129.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG88437.1 - 5.5e-36 124.3 0.0 8e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain BUD22 PF09073.10 GBG88437.1 - 0.0031 16.9 6.9 0.0044 16.4 6.9 1.1 1 0 0 1 1 1 1 BUD22 PQQ_3 PF13570.6 GBG88437.1 - 0.63 10.6 2.5 6.1 7.5 0.2 3.3 3 0 0 3 3 3 0 PQQ-like domain DNA_pol_phi PF04931.13 GBG88437.1 - 1.1 7.3 30.1 1.5 6.8 30.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase_Tyr PF07714.17 GBG88438.1 - 2.2e-37 128.8 0.0 5.5e-37 127.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG88438.1 - 9.9e-36 123.4 0.0 1.5e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG88438.1 - 0.032 14.1 0.2 0.23 11.4 0.2 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4360 PF14273.6 GBG88440.1 - 4.6e-29 101.6 0.1 5.5e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NPCBM_assoc PF10633.9 GBG88440.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Pkinase_Tyr PF07714.17 GBG88441.1 - 2.3e-20 73.0 0.0 1.6e-19 70.3 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG88441.1 - 2.6e-16 59.8 0.0 3.9e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain F-box-like PF12937.7 GBG88443.1 - 1.3e-06 28.2 0.6 3.4e-06 26.8 0.6 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 GBG88443.1 - 8.4e-05 22.3 0.1 0.00026 20.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 GBG88443.1 - 0.00032 21.0 0.3 0.033 14.6 0.4 2.8 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG88443.1 - 0.0086 15.8 0.2 0.049 13.4 0.1 2.2 3 0 0 3 3 3 1 Leucine rich repeat F-box_5 PF18511.1 GBG88443.1 - 0.017 14.6 0.2 0.038 13.6 0.2 1.5 1 0 0 1 1 1 0 F-box LRR_6 PF13516.6 GBG88443.1 - 0.021 14.9 1.1 2.8 8.2 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat DDE_Tnp_4 PF13359.6 GBG88445.1 - 8.1e-23 80.8 0.0 1.6e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88445.1 - 2.8e-09 36.9 0.0 0.0011 18.6 0.0 2.2 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88445.1 - 0.0003 20.5 0.4 0.0091 15.7 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG88446.1 - 2e-07 31.3 1.8 2e-07 31.3 1.8 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG88446.1 - 0.015 15.3 2.3 0.02 15.0 0.5 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG88446.1 - 0.029 14.6 0.3 0.12 12.6 0.2 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 GBG88446.1 - 0.033 15.2 2.1 0.16 13.0 1.0 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG88446.1 - 0.052 13.9 2.1 0.085 13.2 0.3 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like F-box-like PF12937.7 GBG88447.1 - 5e-06 26.3 0.7 1.2e-05 25.0 0.7 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GBG88447.1 - 1.4e-05 25.3 3.7 0.042 14.3 0.4 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG88447.1 - 5.9e-05 22.8 0.2 0.00017 21.3 0.2 1.8 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 GBG88447.1 - 0.0086 15.8 1.8 0.015 15.1 0.2 2.2 3 0 0 3 3 3 1 Leucine rich repeat F-box_5 PF18511.1 GBG88447.1 - 0.016 14.7 0.2 0.041 13.5 0.2 1.6 1 0 0 1 1 1 0 F-box LRR_6 PF13516.6 GBG88447.1 - 0.019 15.0 4.8 3 8.1 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Myb_DNA-bind_4 PF13837.6 GBG88448.1 - 4.2e-07 30.3 1.8 8e-07 29.4 1.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG88448.1 - 0.011 16.1 0.8 0.021 15.1 0.8 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVT_1 PF00078.27 GBG88449.1 - 3.1e-31 108.6 0.1 4.9e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG88449.1 - 3.2e-06 27.7 0.0 7.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88449.1 - 3.5e-05 24.3 0.0 0.00011 22.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88449.1 - 0.00049 19.9 0.0 0.0014 18.4 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG88449.1 - 0.00075 19.7 0.1 0.00075 19.7 0.1 3.5 4 1 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG88449.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4618 PF15397.6 GBG88449.1 - 0.064 12.7 2.8 0.095 12.1 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) gag-asp_proteas PF13975.6 GBG88450.1 - 3.9e-05 24.1 0.0 0.00011 22.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88450.1 - 0.018 15.7 0.0 0.056 14.1 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG88450.1 - 0.02 14.7 0.4 0.039 13.7 0.4 1.4 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG88450.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain RVP PF00077.20 GBG88450.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG88452.1 - 2.3e-07 30.6 6.0 5.8e-07 29.3 6.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG88452.1 - 0.0098 15.6 0.8 0.028 14.1 0.8 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger SAP PF02037.27 GBG88452.1 - 0.027 14.2 0.1 0.075 12.8 0.1 1.8 1 0 0 1 1 1 0 SAP domain RT_RNaseH_2 PF17919.1 GBG88453.1 - 6.8e-30 103.1 0.0 1.2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88453.1 - 2e-25 89.1 0.0 3.4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88453.1 - 5.4e-12 45.7 0.1 7.6e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG88453.1 - 3.8 5.7 14.6 5.5 5.1 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG88453.1 - 7.8 5.1 6.3 12 4.5 6.3 1.2 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 GBG88453.1 - 9.8 5.1 8.9 14 4.6 8.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SET PF00856.28 GBG88454.1 - 0.0038 17.6 0.0 0.036 14.5 0.0 2.2 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GBG88454.1 - 0.0058 17.3 0.3 0.026 15.2 0.3 2.0 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding DNA_gyraseA_C PF03989.13 GBG88454.1 - 0.027 13.9 0.0 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller SET PF00856.28 GBG88455.1 - 0.0072 16.7 0.0 0.054 13.9 0.0 2.2 2 1 0 2 2 2 1 SET domain DNA_gyraseA_C PF03989.13 GBG88455.1 - 0.037 13.5 0.0 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller AFOR_N PF02730.15 GBG88456.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain DUF659 PF04937.15 GBG88457.1 - 1.9e-17 63.5 0.0 5.9e-17 61.9 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVP_2 PF08284.11 GBG88457.1 - 0.044 13.6 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RRN3 PF05327.11 GBG88458.1 - 1.5 7.2 10.4 2.6 6.5 10.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 GBG88458.1 - 4.5 7.2 24.2 6.1 6.7 24.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH PF17917.1 GBG88459.1 - 2.1e-19 69.7 0.0 4.1e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88459.1 - 1.3e-18 66.8 0.0 2.9e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88459.1 - 7.7e-13 48.3 0.2 7.7e-13 48.3 0.2 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG88459.1 - 1.3e-12 48.0 0.0 3.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG88459.1 - 1.7e-07 31.7 0.0 6.6e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88459.1 - 0.00019 22.0 0.0 0.00056 20.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88459.1 - 0.02 14.7 0.5 0.077 12.8 0.2 2.0 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC PF00098.23 GBG88459.1 - 0.028 14.5 1.6 0.1 12.7 1.6 2.1 1 0 0 1 1 1 0 Zinc knuckle Sporozoite_P67 PF05642.11 GBG88459.1 - 0.096 10.8 0.5 0.24 9.5 0.0 1.8 1 1 1 2 2 2 0 Sporozoite P67 surface antigen RVT_1 PF00078.27 GBG88460.1 - 1.4e-26 93.4 0.1 1.7e-26 93.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4224 PF13986.6 GBG88460.1 - 0.085 12.8 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) DUF726 PF05277.12 GBG88461.1 - 1.7e-27 96.3 0.0 2.1e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF3089 PF11288.8 GBG88461.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) VirJ PF06057.11 GBG88461.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Peptidase_A22B PF04258.13 GBG88462.1 - 5.9e-27 94.9 12.5 8.8e-27 94.3 12.5 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 GBG88462.1 - 5.7e-12 45.5 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF3671 PF12420.8 GBG88462.1 - 0.01 15.9 0.1 0.023 14.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function Presenilin PF01080.17 GBG88462.1 - 6.8 5.3 11.4 11 4.6 11.4 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_A22B PF04258.13 GBG88463.1 - 5.8e-27 94.9 12.5 8.7e-27 94.4 12.5 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 GBG88463.1 - 5.5e-12 45.5 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF3671 PF12420.8 GBG88463.1 - 0.0095 16.0 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function Presenilin PF01080.17 GBG88463.1 - 2.7 6.7 11.7 4.4 6.0 11.7 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_A22B PF04258.13 GBG88464.1 - 6e-27 94.9 12.5 8.8e-27 94.4 12.5 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 GBG88464.1 - 6e-12 45.4 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF3671 PF12420.8 GBG88464.1 - 0.01 15.9 0.1 0.023 14.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function Presenilin PF01080.17 GBG88464.1 - 6.8 5.4 11.4 11 4.6 11.4 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_A22B PF04258.13 GBG88465.1 - 2.2e-10 40.5 0.0 2.5e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Signal peptide peptidase EphA2_TM PF14575.6 GBG88466.1 - 1.8e-05 25.5 0.7 0.0023 18.8 0.0 2.9 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Peptidase_S49_N PF08496.10 GBG88466.1 - 0.0027 17.8 0.0 0.039 14.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S49 N-terminal TMEM154 PF15102.6 GBG88466.1 - 0.0028 17.6 0.4 0.022 14.7 0.1 2.3 2 1 0 2 2 2 1 TMEM154 protein family SARAF PF06682.12 GBG88466.1 - 0.02 14.5 0.2 0.041 13.5 0.1 1.7 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 GBG88466.1 - 0.021 15.8 0.0 12 6.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Cadherin_C_2 PF16492.5 GBG88466.1 - 0.037 14.8 0.0 0.23 12.2 0.0 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Shisa PF13908.6 GBG88466.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 GBG88466.1 - 0.1 12.5 0.8 0.24 11.4 0.8 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Rhabdo_glycop PF00974.18 GBG88466.1 - 0.13 10.7 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Adeno_E3_CR2 PF02439.15 GBG88466.1 - 0.13 12.0 4.7 0.36 10.6 4.7 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FAM176 PF14851.6 GBG88466.1 - 0.21 11.2 7.8 1.9 8.1 0.0 2.5 3 0 0 3 3 3 0 FAM176 family Protocadherin PF08374.11 GBG88466.1 - 1.6 8.7 4.0 0.37 10.7 0.2 1.8 2 1 0 2 2 2 0 Protocadherin Peptidase_C97 PF05903.14 GBG88467.1 - 9.2e-39 132.7 0.1 1.2e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 GBG88467.1 - 0.0094 16.3 0.1 0.019 15.3 0.1 1.5 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF1682 PF07946.14 GBG88468.1 - 0.023 13.9 4.1 0.034 13.4 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) BUD22 PF09073.10 GBG88468.1 - 0.036 13.4 8.4 0.049 13.0 8.4 1.1 1 0 0 1 1 1 0 BUD22 Retrotrans_gag PF03732.17 GBG88470.1 - 0.025 14.9 0.4 0.11 12.8 0.0 2.4 3 0 0 3 3 3 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG88471.1 - 2.3e-35 122.1 0.0 4.1e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88471.1 - 1.2e-29 102.3 0.0 2.7e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88471.1 - 1.1e-28 99.6 0.1 2.2e-28 98.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4392 PF14336.6 GBG88471.1 - 0.047 13.1 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Phage_GPO PF05929.11 GBG88471.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RVP_2 PF08284.11 GBG88471.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RepB-RCR_reg PF10723.9 GBG88474.1 - 0.037 14.0 0.2 0.12 12.3 0.1 2.0 1 1 0 1 1 1 0 Replication regulatory protein RepB Hemerythrin PF01814.23 GBG88474.1 - 0.15 12.7 8.1 0.81 10.3 3.8 2.5 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Slx4 PF09494.10 GBG88474.1 - 0.16 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Slx4 endonuclease PLATZ PF04640.14 GBG88474.1 - 0.41 11.3 2.2 1 10.0 0.2 2.5 2 0 0 2 2 2 0 PLATZ transcription factor bPH_2 PF03703.14 GBG88475.1 - 1.6e-10 41.0 0.1 2.8e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial PH domain Pkinase_Tyr PF07714.17 GBG88476.1 - 4.5e-22 78.6 0.0 7e-13 48.5 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG88476.1 - 2.3e-18 66.5 0.0 7.8e-09 35.3 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Myb_DNA-bind_4 PF13837.6 GBG88477.1 - 1.1e-08 35.3 0.4 1.1e-08 35.3 0.4 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain BSMAP PF12280.8 GBG88480.1 - 8.5 6.5 8.1 0.43 10.7 1.6 2.2 2 0 0 2 2 2 0 Brain specific membrane anchored protein rve PF00665.26 GBG88481.1 - 4.8e-12 46.1 0.0 1.9e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG88481.1 - 3.4e-11 43.1 1.5 4.6e-11 42.6 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG88482.1 - 0.038 14.1 1.1 0.089 12.9 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2407_C PF13373.6 GBG88482.1 - 4.7 7.4 7.9 12 6.0 7.7 1.8 1 1 0 1 1 1 0 DUF2407 C-terminal domain LMBR1 PF04791.16 GBG88483.1 - 2.5 6.9 4.6 3.4 6.5 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5401 PF17380.2 GBG88483.1 - 5.4 5.0 44.4 6.5 4.7 44.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DZR PF12773.7 GBG88484.1 - 0.078 13.0 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 Double zinc ribbon RNA_pol_N PF01194.17 GBG88484.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit CTU2 PF10288.9 GBG88484.1 - 0.44 10.8 2.8 0.47 10.7 0.5 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 LRR_4 PF12799.7 GBG88485.1 - 2.4e-16 59.6 17.2 0.00029 21.1 0.2 5.6 3 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG88485.1 - 1.4e-12 47.2 19.7 9.7e-06 25.3 1.4 4.4 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 GBG88485.1 - 1.2e-10 41.2 4.9 8.7e-07 28.6 0.2 3.1 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 GBG88485.1 - 0.045 13.8 17.5 0.97 9.7 0.2 6.2 7 0 0 7 7 7 0 Leucine Rich repeat Imm27 PF15590.6 GBG88485.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 27 LRR_1 PF00560.33 GBG88485.1 - 7.7 7.5 16.0 65 4.7 1.4 6.4 6 1 0 6 6 6 0 Leucine Rich Repeat DUF659 PF04937.15 GBG88486.1 - 6.3e-15 55.4 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88486.1 - 1.2e-06 28.2 0.1 2.2e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PAXIP1_C PF15364.6 GBG88487.1 - 0.0062 16.8 6.1 0.0089 16.3 6.1 1.2 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein DUF2722 PF10846.8 GBG88487.1 - 0.01 14.8 2.0 0.012 14.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CCDC106 PF15794.5 GBG88487.1 - 0.021 14.6 2.1 0.027 14.2 2.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 GBG88487.1 - 0.026 12.8 12.5 0.032 12.5 12.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 GBG88487.1 - 0.092 12.7 21.8 0.11 12.4 21.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop53 PF07767.11 GBG88487.1 - 0.11 11.9 17.8 0.14 11.5 17.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) alpha-hel2 PF14456.6 GBG88487.1 - 0.2 10.9 2.6 0.28 10.5 2.6 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 Nop14 PF04147.12 GBG88487.1 - 0.23 9.6 18.3 0.28 9.3 18.3 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG88487.1 - 0.38 9.1 15.7 0.47 8.8 15.7 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GBG88487.1 - 0.42 10.0 15.1 0.54 9.6 15.1 1.1 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG88487.1 - 0.47 10.7 9.8 0.59 10.4 9.8 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated RR_TM4-6 PF06459.12 GBG88487.1 - 0.61 9.9 8.1 0.76 9.5 8.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 GBG88487.1 - 0.87 9.2 9.2 1.3 8.7 9.2 1.3 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 GBG88487.1 - 1.3 8.2 6.5 1.7 7.8 6.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 GBG88487.1 - 1.3 7.0 21.4 0.12 10.4 17.1 1.4 2 0 0 2 2 2 0 DNA polymerase phi NOA36 PF06524.12 GBG88487.1 - 1.8 7.8 12.7 2.6 7.3 12.7 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 GBG88487.1 - 2.1 7.4 19.3 2.6 7.1 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 GBG88487.1 - 5.4 5.4 9.6 6.5 5.2 9.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 GBG88487.1 - 6.2 5.5 5.8 7.3 5.2 5.8 1.1 1 0 0 1 1 1 0 Presenilin SspB PF04386.13 GBG88487.1 - 7.6 6.4 8.1 11 5.9 8.1 1.2 1 0 0 1 1 1 0 Stringent starvation protein B DPBB_1 PF03330.18 GBG88488.1 - 5e-14 52.3 1.1 1.2e-13 51.2 0.0 2.1 3 0 0 3 3 3 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG88488.1 - 3.7e-10 39.7 0.0 6.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen DUF659 PF04937.15 GBG88489.1 - 9.3e-37 126.2 0.0 3.1e-36 124.5 0.0 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF 659) Peptidase_M10_C PF08548.11 GBG88489.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal DUF659 PF04937.15 GBG88490.1 - 1.5e-17 63.8 0.1 2.5e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88490.1 - 1.4e-07 31.1 0.5 3.1e-07 30.1 0.5 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DPBB_1 PF03330.18 GBG88491.1 - 1.1e-14 54.4 1.4 1.8e-14 53.8 0.1 2.0 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG88491.1 - 5.1e-10 39.2 0.0 9.5e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Pollen allergen DUF5348 PF17295.2 GBG88491.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) RVT_1 PF00078.27 GBG88492.1 - 1.1e-29 103.6 0.1 1.6e-29 103.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG88492.1 - 1.1e-08 34.9 0.0 2.5e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88492.1 - 2.9e-06 27.8 0.0 8.1e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88492.1 - 6.4e-05 23.4 0.0 0.00016 22.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88492.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF4360 PF14273.6 GBG88494.1 - 3.7e-30 105.1 0.7 4.1e-30 105.0 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF5011 PF16403.5 GBG88494.1 - 0.026 14.6 0.1 0.058 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) DUF659 PF04937.15 GBG88495.1 - 1.5e-05 24.9 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cwf_Cwc_15 PF04889.12 GBG88495.1 - 0.0078 16.0 5.7 0.036 13.8 5.7 2.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 GBG88495.1 - 1.2 9.0 11.3 13 5.6 11.3 2.6 1 1 0 1 1 1 0 Sigma-70, non-essential region zf-CCHC PF00098.23 GBG88496.1 - 1.6e-07 31.0 1.1 3e-07 30.2 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle LPP PF04728.13 GBG88496.1 - 0.86 10.0 12.2 2.5 8.5 0.9 3.8 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Med26_C PF15693.5 GBG88496.1 - 0.93 9.6 8.6 2.8 8.1 8.6 1.8 1 1 0 1 1 1 0 Mediator complex subunit 26 C-terminal ALMT PF11744.8 GBG88496.1 - 2.3 7.0 7.4 3.5 6.3 7.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Prok-RING_4 PF14447.6 GBG88496.1 - 5.5 6.9 6.2 0.39 10.6 1.2 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 SNARE_assoc PF09335.11 GBG88497.1 - 4.1e-23 82.2 11.4 4.1e-23 82.2 11.4 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF4820 PF16091.5 GBG88498.1 - 0.017 14.5 0.7 0.024 14.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Cellulose_synt PF03552.14 GBG88498.1 - 0.17 10.4 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Cellulose synthase FAM176 PF14851.6 GBG88498.1 - 0.22 11.2 5.8 0.35 10.5 5.8 1.3 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 GBG88498.1 - 2.6 6.7 3.7 3.4 6.3 3.7 1.1 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG88499.1 - 6.6e-24 83.9 0.0 1.4e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88499.1 - 3.3e-22 78.7 0.0 1.3e-21 76.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88499.1 - 1.2e-15 57.4 3.9 1.4e-15 57.1 1.0 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG88499.1 - 2e-11 44.1 0.5 8.5e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain DUF4187 PF13821.6 GBG88499.1 - 0.014 15.2 0.4 0.036 13.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG88499.1 - 0.099 12.9 0.6 0.82 10.0 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein DUF4482 PF14818.6 GBG88500.1 - 0.06 14.2 5.3 0.12 13.2 5.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) DUF4407 PF14362.6 GBG88500.1 - 0.14 11.5 1.7 0.15 11.4 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG17 PF04108.12 GBG88500.1 - 1.4 8.0 10.1 0.064 12.4 4.7 1.4 2 0 0 2 2 2 0 Autophagy protein Apg17 Myb_DNA-bind_4 PF13837.6 GBG88501.1 - 5.8e-07 29.8 0.6 1.1e-06 29.0 0.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG88501.1 - 0.0022 18.0 0.5 0.0054 16.8 0.5 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CoA_binding_3 PF13727.6 GBG88501.1 - 0.0028 17.7 0.5 0.0061 16.6 0.3 1.6 2 0 0 2 2 2 1 CoA-binding domain MADF_DNA_bdg PF10545.9 GBG88501.1 - 0.014 15.7 0.7 0.04 14.2 0.7 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG88502.1 - 1.3e-27 96.4 0.0 1.7e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88502.1 - 3.6e-17 62.6 0.0 5.3e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88502.1 - 1.1e-05 25.2 0.2 0.00092 18.9 0.0 2.1 2 0 0 2 2 2 2 Transposase DDE domain Serinc PF03348.15 GBG88503.1 - 0.11 11.4 0.2 0.16 10.9 0.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nop53 PF07767.11 GBG88503.1 - 0.15 11.4 27.2 0.21 10.9 27.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BUD22 PF09073.10 GBG88503.1 - 0.46 9.8 31.4 0.61 9.4 31.4 1.1 1 0 0 1 1 1 0 BUD22 Na_trans_assoc PF06512.13 GBG88503.1 - 0.68 10.2 18.4 2.3 8.4 18.5 1.8 1 1 0 1 1 1 0 Sodium ion transport-associated SAPS PF04499.15 GBG88503.1 - 0.97 8.1 7.6 1.2 7.9 7.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG88503.1 - 1.3 7.2 29.9 1.6 6.8 29.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG88503.1 - 2.7 7.4 31.2 3.7 6.9 31.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG88503.1 - 2.8 6.1 22.5 3.7 5.7 22.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG88503.1 - 5.6 6.4 18.6 8.5 5.8 18.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NPR3 PF03666.13 GBG88503.1 - 7.6 5.2 10.4 11 4.7 10.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RT_RNaseH_2 PF17919.1 GBG88505.1 - 4.5e-27 94.0 0.0 1e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88505.1 - 4.7e-26 91.1 0.0 1.2e-25 89.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88505.1 - 2.1e-19 69.3 0.6 4.9e-19 68.2 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG88505.1 - 0.0021 18.3 0.1 0.0021 18.3 0.1 3.2 5 0 0 5 5 5 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG88505.1 - 0.088 13.0 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger HIP1_clath_bdg PF16515.5 GBG88505.1 - 0.093 13.3 0.4 0.093 13.3 0.4 3.0 4 0 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Barttin PF15462.6 GBG88505.1 - 0.96 9.2 3.3 8.8 6.0 0.1 2.5 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Kazal_1 PF00050.21 GBG88506.1 - 1.3e-13 50.7 13.3 1.4e-07 31.4 3.4 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 GBG88506.1 - 2.4e-11 43.6 11.8 7.4e-06 26.0 3.0 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Retrotrans_gag PF03732.17 GBG88506.1 - 0.024 14.9 0.2 0.12 12.7 0.0 2.3 2 1 0 2 2 2 0 Retrotransposon gag protein LAP1C PF05609.12 GBG88506.1 - 0.2 10.7 15.1 0.26 10.3 15.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG88506.1 - 1.1 7.4 21.8 1.6 6.9 21.8 1.2 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG88506.1 - 1.1 7.6 28.1 4 5.7 28.1 1.8 1 1 0 1 1 1 0 Mpp10 protein ALMT PF11744.8 GBG88506.1 - 6.7 5.4 6.2 9.2 5.0 6.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Vac_ImportDeg PF09783.9 GBG88507.1 - 0.38 10.6 3.6 20 5.0 3.6 2.4 1 1 0 1 1 1 0 Vacuolar import and degradation protein Herpes_UL52 PF03121.15 GBG88508.1 - 0.022 14.7 1.7 0.038 13.9 1.7 1.3 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase PKS_DE PF18369.1 GBG88508.1 - 0.09 13.4 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain DUF659 PF04937.15 GBG88509.1 - 8.1e-13 48.5 0.1 1.4e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SDA1 PF05285.12 GBG88509.1 - 0.7 9.3 13.6 1.1 8.7 13.6 1.2 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 GBG88510.1 - 1.2e-16 60.9 0.0 5.5e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 GBG88510.1 - 3.4e-08 34.0 11.5 2.7e-06 28.0 0.1 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 GBG88510.1 - 4.5e-06 27.0 11.9 0.043 14.2 0.3 4.4 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.22 GBG88510.1 - 0.00053 20.0 23.4 0.04 14.2 0.2 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 GBG88510.1 - 0.00077 19.9 20.6 0.0055 17.2 3.8 5.5 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 GBG88510.1 - 0.0034 17.5 0.4 0.29 11.2 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 GBG88510.1 - 0.0043 16.4 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Adaptin_N PF01602.20 GBG88510.1 - 0.012 14.2 1.6 0.19 10.2 0.4 2.7 3 0 0 3 3 3 0 Adaptin N terminal region Pex24p PF06398.11 GBG88510.1 - 0.22 10.5 7.9 0.63 9.0 7.9 1.7 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Arm PF00514.23 GBG88510.1 - 0.41 10.8 1.9 1.9 8.6 0.7 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat RT_RNaseH_2 PF17919.1 GBG88511.1 - 2.1e-16 59.8 0.0 4.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88511.1 - 9.1e-15 54.8 0.0 1.8e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88511.1 - 4.9e-09 36.0 0.0 7.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88512.1 - 8.3e-26 89.9 0.0 2.7e-25 88.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88512.1 - 3.5e-25 88.3 0.0 8.6e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88512.1 - 1.9e-24 86.4 0.1 1.9e-24 86.4 0.1 2.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88512.1 - 1.9e-16 59.9 0.1 4.6e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG88512.1 - 0.0034 17.6 0.0 0.015 15.6 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG88512.1 - 0.0088 15.8 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF2615 PF11027.8 GBG88514.1 - 0.0085 16.2 1.8 0.016 15.3 1.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2615) Serinc PF03348.15 GBG88514.1 - 0.18 10.7 0.4 0.21 10.5 0.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1676 PF07898.13 GBG88514.1 - 0.22 11.5 4.6 0.38 10.8 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) SAPS PF04499.15 GBG88514.1 - 1.1 8.0 6.5 0.95 8.2 6.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Conotoxin PF02950.17 GBG88514.1 - 6 8.0 9.8 0.23 12.5 1.3 2.5 1 1 1 2 2 2 0 Conotoxin SR-25 PF10500.9 GBG88518.1 - 0.0011 18.6 22.8 0.0013 18.4 22.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 GBG88518.1 - 0.0086 16.3 21.2 0.01 16.1 21.2 1.2 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 DUF5327 PF17261.2 GBG88518.1 - 0.011 16.5 8.2 0.018 15.8 8.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Dicty_REP PF05086.12 GBG88518.1 - 0.052 11.5 22.9 0.058 11.4 22.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Eapp_C PF10238.9 GBG88518.1 - 0.1 12.7 9.9 0.12 12.5 9.9 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein FHIPEP PF00771.20 GBG88518.1 - 0.13 10.7 4.0 0.15 10.5 4.0 1.0 1 0 0 1 1 1 0 FHIPEP family Ribosomal_60s PF00428.19 GBG88518.1 - 0.13 12.8 10.6 0.23 12.1 10.6 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein Baculo_PP31 PF05311.11 GBG88518.1 - 0.14 11.6 17.9 0.15 11.5 17.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FAM176 PF14851.6 GBG88518.1 - 0.17 11.6 4.4 0.2 11.3 4.4 1.2 1 0 0 1 1 1 0 FAM176 family HA2 PF04408.23 GBG88518.1 - 0.21 11.9 4.0 0.24 11.7 4.0 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) Med19 PF10278.9 GBG88518.1 - 0.24 11.3 26.0 0.28 11.1 26.0 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Mucin PF01456.17 GBG88518.1 - 0.24 11.4 21.6 0.25 11.3 21.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MAP17 PF15807.5 GBG88518.1 - 0.25 11.6 11.3 0.35 11.1 11.3 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Coilin_N PF15862.5 GBG88518.1 - 0.28 11.0 20.1 0.36 10.6 20.1 1.1 1 0 0 1 1 1 0 Coilin N-terminus DUF3824 PF12868.7 GBG88518.1 - 0.29 11.8 5.7 0.38 11.4 5.7 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF4820 PF16091.5 GBG88518.1 - 0.33 10.3 7.6 0.39 10.1 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ASD2 PF08687.11 GBG88518.1 - 0.4 10.2 12.0 0.45 10.0 12.0 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Med3 PF11593.8 GBG88518.1 - 0.44 9.7 18.3 0.48 9.6 18.3 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3807 PF12720.7 GBG88518.1 - 0.52 10.6 18.7 0.61 10.3 18.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Serinc PF03348.15 GBG88518.1 - 0.56 9.1 6.7 0.62 8.9 6.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) O-antigen_lig PF13425.6 GBG88518.1 - 0.56 8.9 9.7 0.6 8.8 9.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein O-ag_pol_Wzy PF14296.6 GBG88518.1 - 0.61 8.7 4.2 0.66 8.6 4.2 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy SID-1_RNA_chan PF13965.6 GBG88518.1 - 0.61 8.4 3.0 0.7 8.2 3.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Casc1 PF12366.8 GBG88518.1 - 0.69 9.4 13.6 0.76 9.3 13.6 1.0 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DDHD PF02862.17 GBG88518.1 - 0.82 9.8 10.8 0.94 9.6 10.8 1.0 1 0 0 1 1 1 0 DDHD domain AJAP1_PANP_C PF15298.6 GBG88518.1 - 0.84 9.8 15.2 0.98 9.6 15.2 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus CCDC106 PF15794.5 GBG88518.1 - 1 9.0 18.6 1.3 8.7 18.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CBP_BcsG PF11658.8 GBG88518.1 - 1.1 7.6 5.4 1.2 7.5 5.4 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG 7TM_GPCR_Srx PF10328.9 GBG88518.1 - 1.1 8.8 5.5 1.3 8.6 5.5 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PPL5 PF18168.1 GBG88518.1 - 1.1 8.4 12.9 1.2 8.3 12.9 1.0 1 0 0 1 1 1 0 Prim-pol family 5 SelP_N PF04592.14 GBG88518.1 - 1.2 8.4 8.7 1.2 8.5 8.7 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BSP_II PF05432.11 GBG88518.1 - 1.4 8.6 15.1 2 8.0 15.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Tim54 PF11711.8 GBG88518.1 - 1.4 7.6 16.1 1.6 7.5 16.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM164 PF14808.6 GBG88518.1 - 1.4 8.2 3.2 1.5 8.1 3.2 1.0 1 0 0 1 1 1 0 TMEM164 family ORC_WH_C PF18137.1 GBG88518.1 - 1.5 8.9 9.6 1.6 8.8 9.6 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Dpy19 PF10034.9 GBG88518.1 - 1.6 6.8 5.2 1.8 6.7 5.2 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Peptidase_S49_N PF08496.10 GBG88518.1 - 1.8 8.7 19.9 2.1 8.4 19.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 GBG88518.1 - 1.9 8.2 16.8 2.2 8.1 16.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FancD2 PF14631.6 GBG88518.1 - 2 5.7 11.0 2.1 5.6 11.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease U1snRNP70_N PF12220.8 GBG88518.1 - 2.2 9.0 16.2 3 8.6 16.2 1.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RNA_polI_A34 PF08208.11 GBG88518.1 - 2.7 8.1 29.8 3.4 7.7 29.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Jak1_Phl PF17887.1 GBG88518.1 - 3 7.8 13.2 3.5 7.6 13.2 1.2 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain 7TM_GPCR_Sru PF10322.9 GBG88518.1 - 3.1 7.1 8.2 3.7 6.8 8.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru 7TM_GPCR_Srv PF10323.9 GBG88518.1 - 3.1 7.1 5.3 3.8 6.8 5.3 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF3899 PF13038.6 GBG88518.1 - 3.6 8.2 4.9 4.8 7.8 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Hydin_ADK PF17213.3 GBG88518.1 - 3.7 7.8 11.0 4 7.7 11.0 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain GAGA_bind PF06217.12 GBG88518.1 - 3.8 7.7 19.1 4.4 7.5 19.1 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3537 PF12056.8 GBG88518.1 - 3.9 6.2 5.8 4 6.2 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Cellulose_synt PF03552.14 GBG88518.1 - 3.9 5.8 8.4 3.9 5.8 8.4 1.0 1 0 0 1 1 1 0 Cellulose synthase MDM31_MDM32 PF08118.11 GBG88518.1 - 4.6 5.8 12.3 5.1 5.6 12.3 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins ORC6 PF05460.13 GBG88518.1 - 4.9 6.3 17.2 5.6 6.1 17.2 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF2828 PF11443.8 GBG88518.1 - 5 5.1 14.9 5.2 5.0 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) STAG PF08514.11 GBG88518.1 - 5.2 7.0 19.1 6.6 6.7 19.1 1.2 1 0 0 1 1 1 0 STAG domain DUF5058 PF16481.5 GBG88518.1 - 5.6 6.6 7.0 6.1 6.5 7.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) MID_MedPIWI PF18296.1 GBG88518.1 - 6.4 6.5 10.6 6.9 6.4 10.6 1.0 1 0 0 1 1 1 0 MID domain of medPIWI DUF4569 PF15133.6 GBG88518.1 - 6.4 6.4 11.3 7.3 6.2 11.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) RNA_pol_Rpc4 PF05132.14 GBG88518.1 - 6.4 7.2 15.9 7 7.1 15.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 V_ATPase_I PF01496.19 GBG88518.1 - 6.5 4.5 11.4 7.5 4.3 11.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 GBG88518.1 - 6.8 6.4 12.7 7.7 6.2 12.7 1.1 1 0 0 1 1 1 0 Connexin FixO PF02433.15 GBG88518.1 - 7 6.0 9.5 7.4 6.0 9.5 1.0 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Rot1 PF10681.9 GBG88518.1 - 7.1 6.1 10.6 7.7 6.0 10.6 1.1 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Vfa1 PF08432.10 GBG88518.1 - 8.4 6.7 23.7 10 6.4 23.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CAP_N PF01213.19 GBG88521.1 - 0.0091 15.5 1.7 0.011 15.2 1.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PilX_N PF14341.6 GBG88521.1 - 3.9 7.5 7.3 0.73 9.8 0.9 2.3 2 0 0 2 2 2 0 PilX N-terminal PE_PPE_C PF12484.8 GBG88521.1 - 6.1 7.8 15.2 4.5 8.2 8.6 2.2 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal RVT_1 PF00078.27 GBG88524.1 - 1.7e-24 86.6 0.0 2.5e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG88524.1 - 0.0068 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 RVT_1 PF00078.27 GBG88525.1 - 1.1e-24 87.1 0.0 1.7e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG88525.1 - 0.0049 16.0 0.0 0.0084 15.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 Cadherin-like PF12733.7 GBG88526.1 - 0.027 15.0 0.0 0.23 12.0 0.0 2.6 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain RVT_1 PF00078.27 GBG88527.1 - 6.8e-21 74.8 0.0 1.5e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 GBG88527.1 - 0.0062 16.4 0.0 0.079 12.8 0.0 2.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Synaptobrevin PF00957.21 GBG88527.1 - 3.9 7.3 9.9 32 4.4 0.0 2.7 2 0 0 2 2 2 0 Synaptobrevin RT_RNaseH_2 PF17919.1 GBG88528.1 - 1e-25 89.6 0.0 2.5e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glyco_transf_29 PF00777.18 GBG88528.1 - 1.3e-25 90.4 0.0 2.9e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 29 (sialyltransferase) RT_RNaseH PF17917.1 GBG88528.1 - 3e-13 50.0 0.0 6.4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88528.1 - 4.1e-11 42.8 0.1 8.6e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTB PF00651.31 GBG88529.1 - 4.3e-33 113.9 0.0 1.9e-15 57.0 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 GBG88529.1 - 9e-08 32.5 0.0 3e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG88529.1 - 1.7e-05 25.0 0.3 5.2e-05 23.4 0.3 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG88529.1 - 3.1e-05 24.0 0.6 0.047 14.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 GBG88529.1 - 0.00016 22.2 0.0 0.00039 20.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) BACK PF07707.15 GBG88529.1 - 0.0031 17.6 0.0 0.0091 16.1 0.0 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ank PF00023.30 GBG88529.1 - 0.0037 17.7 0.4 0.78 10.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Prok-JAB PF14464.6 GBG88529.1 - 0.068 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain FAM176 PF14851.6 GBG88529.1 - 1.3 8.7 9.7 3.2 7.4 2.6 2.5 2 0 0 2 2 2 0 FAM176 family Filamin PF00630.19 GBG88530.1 - 1.6e-21 77.0 0.2 4.7e-21 75.5 0.2 1.9 1 0 0 1 1 1 1 Filamin/ABP280 repeat RRM_1 PF00076.22 GBG88530.1 - 6.5e-09 35.5 0.7 1.2e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Invasin_D3 PF09134.10 GBG88530.1 - 2.8e-05 24.4 1.1 0.00011 22.5 1.1 2.0 1 0 0 1 1 1 1 Invasin, domain 3 YtkA PF13115.6 GBG88530.1 - 0.0028 18.2 0.5 0.012 16.2 0.5 2.1 1 0 0 1 1 1 1 YtkA-like RRM_occluded PF16842.5 GBG88530.1 - 0.0074 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_2 PF14608.6 GBG88530.1 - 0.0096 16.4 2.5 0.017 15.6 2.5 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 GBG88530.1 - 0.017 15.0 1.0 0.034 14.1 1.0 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SAM_1 PF00536.30 GBG88531.1 - 9.4e-06 26.0 0.0 1.3e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GBG88531.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DNA_pol_phi PF04931.13 GBG88531.1 - 2.8 5.9 12.7 3.5 5.6 12.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG88531.1 - 3.5 5.7 11.9 4.1 5.5 11.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG88531.1 - 5.3 5.2 11.5 5.8 5.1 11.5 1.0 1 0 0 1 1 1 0 CDC45-like protein PEP_mutase PF13714.6 GBG88532.1 - 4.6e-48 163.8 1.3 1e-47 162.7 1.3 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GBG88532.1 - 2.5e-10 39.5 0.3 5.3e-10 38.4 0.3 1.5 1 0 0 1 1 1 1 Isocitrate lyase family SHIPPO-rpt PF07004.12 GBG88533.1 - 0.0018 19.1 28.1 5.4 8.1 0.1 7.3 7 0 0 7 7 7 5 Sperm-tail PG-rich repeat EphA2_TM PF14575.6 GBG88533.1 - 0.1 13.5 0.1 0.35 11.8 0.1 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 GBG88533.1 - 0.12 12.6 0.9 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2570 PF10828.8 GBG88533.1 - 0.2 11.5 1.7 0.44 10.4 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Topo_Zn_Ribbon PF08272.11 GBG88534.1 - 0.19 11.4 1.3 0.38 10.4 0.1 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG88534.1 - 0.34 11.1 1.9 0.75 10.0 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG88535.1 - 9.2e-23 80.5 0.0 2.4e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88535.1 - 5.3e-21 74.5 0.0 1.1e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88535.1 - 2.2e-19 69.3 0.3 5.6e-19 68.0 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88535.1 - 1.2e-17 64.2 0.0 2.9e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG88535.1 - 1.2e-06 28.2 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG88535.1 - 0.00044 20.8 0.0 0.00097 19.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88535.1 - 0.0024 17.7 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88535.1 - 0.0089 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88535.1 - 0.014 16.0 0.1 0.038 14.6 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG88535.1 - 0.14 12.4 0.3 0.33 11.2 0.3 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Glyoxalase PF00903.25 GBG88536.1 - 3.4e-43 146.9 0.1 2.2e-21 76.4 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GBG88536.1 - 1.5e-16 60.6 0.0 2.6e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GBG88536.1 - 8.6e-12 45.8 0.0 3.3e-06 27.8 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.6 GBG88536.1 - 1.6e-06 28.2 0.0 0.059 13.4 0.0 2.5 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_3 PF13468.6 GBG88536.1 - 1.1e-05 25.6 0.0 0.37 10.9 0.0 4.1 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 GBG88536.1 - 0.023 14.6 0.0 8.4 6.4 0.0 2.7 2 2 0 2 2 2 0 Glyoxalase-like domain Glyoxalase PF00903.25 GBG88537.1 - 1.3e-43 148.3 0.1 1.3e-21 77.1 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GBG88537.1 - 5.8e-17 61.9 0.0 1.6e-08 34.8 0.0 2.4 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GBG88537.1 - 3.9e-12 46.9 0.0 2e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.6 GBG88537.1 - 7.7e-07 29.2 0.1 0.039 14.0 0.0 2.5 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_3 PF13468.6 GBG88537.1 - 3.8e-06 27.1 0.0 0.24 11.5 0.0 3.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 GBG88537.1 - 0.0094 15.9 0.0 5.4 7.0 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain RVT_1 PF00078.27 GBG88538.1 - 2.9e-33 115.3 0.0 4.2e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M8 PF01457.16 GBG88538.1 - 1.8e-17 63.2 0.0 2.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin Zds_C PF08632.10 GBG88538.1 - 0.047 13.4 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF5095 PF17016.5 GBG88538.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Glyco_tranf_2_4 PF13704.6 GBG88539.1 - 0.039 14.5 0.3 0.087 13.4 0.3 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 rve PF00665.26 GBG88540.1 - 0.0006 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG88540.1 - 0.0036 17.0 0.3 0.021 14.6 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain DUF2385 PF09539.10 GBG88540.1 - 0.019 15.5 1.1 0.67 10.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) RT_RNaseH PF17917.1 GBG88541.1 - 2.3e-23 82.5 0.0 8.8e-23 80.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88541.1 - 4.1e-22 78.1 0.0 1.1e-21 76.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88541.1 - 4.6e-19 68.8 0.1 2.8e-18 66.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88541.1 - 2.5e-17 62.7 0.1 5.3e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88541.1 - 0.004 17.3 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger JIP_LZII PF16471.5 GBG88541.1 - 0.026 14.7 2.7 0.46 10.7 0.2 3.0 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 GBG88541.1 - 0.027 15.1 0.1 0.027 15.1 0.1 3.5 4 0 0 4 4 4 0 SlyX Cnn_1N PF07989.11 GBG88541.1 - 0.48 10.6 0.0 0.48 10.6 0.0 2.3 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 GBG88541.1 - 0.79 10.0 3.4 25 5.2 0.0 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3510 PF12022.8 GBG88541.1 - 2 8.8 4.9 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Histone PF00125.24 GBG88543.1 - 2.7e-15 56.9 0.2 4.4e-15 56.2 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG88543.1 - 0.018 15.4 0.3 0.034 14.5 0.3 1.4 1 0 0 1 1 1 0 CENP-S protein Foie-gras_1 PF11817.8 GBG88545.1 - 1.4e-08 34.7 2.7 1.5e-07 31.3 0.1 2.3 2 0 0 2 2 2 1 Foie gras liver health family 1 TRAPPC10 PF12584.8 GBG88545.1 - 2.6e-08 33.7 0.0 6.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_12 PF13424.6 GBG88545.1 - 0.0044 17.3 0.1 0.0044 17.3 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG88545.1 - 0.27 12.2 0.1 0.27 12.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG88545.1 - 0.28 11.3 1.4 2.3 8.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4140 PF13600.6 GBG88545.1 - 4.9 7.6 10.1 1 9.8 0.6 3.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Integrase_H2C2 PF17921.1 GBG88546.1 - 3.9e-16 58.9 0.6 1.2e-15 57.4 0.6 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG88546.1 - 4.9e-12 46.1 0.2 2.2e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88546.1 - 8.9e-11 42.0 0.0 2.4e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG88546.1 - 8.9e-07 28.9 0.0 2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG88546.1 - 0.0024 18.1 1.7 0.0058 16.9 0.2 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG88546.1 - 0.0052 17.0 0.5 0.016 15.4 0.5 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF4187 PF13821.6 GBG88546.1 - 0.0069 16.1 0.6 0.02 14.7 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) MCLC PF05934.11 GBG88549.1 - 3.7 6.1 7.5 3.8 6.1 7.5 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Pur_DNA_glyco PF02245.16 GBG88550.1 - 2.2e-49 167.2 0.0 3.7e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) RT_RNaseH_2 PF17919.1 GBG88550.1 - 1.4e-33 114.8 0.1 2.7e-33 114.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88550.1 - 7.5e-28 96.9 0.2 1.4e-27 96.0 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88550.1 - 6.2e-17 61.5 0.1 1.4e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG88550.1 - 3.4e-14 52.9 0.4 2.9e-11 43.3 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG88550.1 - 1.7e-08 34.7 0.0 4.5e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 GBG88551.1 - 1.8e-12 47.5 0.1 3.7e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain DUF2385 PF09539.10 GBG88551.1 - 0.041 14.4 0.1 0.75 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) TetR_C_14 PF17754.1 GBG88551.1 - 0.054 13.4 9.0 0.13 12.3 9.0 1.7 1 0 0 1 1 1 0 MftR C-terminal domain DUF2070 PF09843.9 GBG88551.1 - 0.19 10.0 1.6 0.32 9.2 1.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Integrase_H2C2 PF17921.1 GBG88552.1 - 2.9e-19 68.9 0.0 5.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88552.1 - 0.001 19.2 0.0 0.0083 16.3 0.0 2.6 3 0 0 3 3 3 1 H2C2 zinc finger rve PF00665.26 GBG88552.1 - 0.0012 19.0 0.2 0.0053 16.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG88552.1 - 0.016 15.2 0.3 0.036 14.1 0.3 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase NIR_SIR PF01077.22 GBG88552.1 - 0.062 12.8 1.8 4.9 6.6 0.2 2.4 2 0 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain PLD_C PF12357.8 GBG88554.1 - 1.7e-25 88.7 0.0 2.6e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.22 GBG88554.1 - 2.4e-08 33.8 0.2 3.9e-08 33.1 0.2 1.4 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG88554.1 - 3.9e-07 30.0 0.0 6.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain RVT_1 PF00078.27 GBG88555.1 - 4.6e-29 101.5 0.0 8.3e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C2 PF00168.30 GBG88555.1 - 1.3e-14 54.3 0.0 2.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain Exo_endo_phos PF03372.23 GBG88555.1 - 1.4e-09 37.8 0.2 3e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PLDc PF00614.22 GBG88555.1 - 1.1e-07 31.7 0.1 2.7e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Phospholipase D Active site motif Exo_endo_phos_2 PF14529.6 GBG88555.1 - 0.0016 18.2 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase gag-asp_proteas PF13975.6 GBG88557.1 - 9.3e-09 35.7 0.0 2.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88557.1 - 4.8e-06 27.1 0.0 1.3e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88557.1 - 0.00011 21.9 0.2 0.00045 20.0 0.1 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG88557.1 - 0.0034 17.7 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG88557.1 - 0.046 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.24 GBG88558.1 - 1.9e-23 83.3 3.2 5.2e-22 78.6 1.2 4.1 3 1 0 4 4 4 2 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG88558.1 - 0.018 15.4 2.2 1.9 8.9 0.2 2.7 2 0 0 2 2 2 0 CENP-S protein Pkinase_Tyr PF07714.17 GBG88559.1 - 6.2e-66 222.3 0.0 6.2e-66 222.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG88559.1 - 6.8e-57 192.8 3.7 1.2e-56 192.1 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain ANTH PF07651.16 GBG88559.1 - 2e-13 50.0 0.1 2e-13 50.0 0.1 4.5 4 2 1 5 5 5 2 ANTH domain APH PF01636.23 GBG88559.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Integrase_H2C2 PF17921.1 GBG88562.1 - 2.6e-13 49.8 1.2 3.7e-13 49.4 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG88562.1 - 4.5e-06 27.2 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88562.1 - 3.8e-05 24.2 0.0 8.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG88562.1 - 0.00076 19.7 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF659 PF04937.15 GBG88563.1 - 2.2e-10 40.6 0.1 6.3e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG88564.1 - 1.9e-10 41.0 0.7 4.4e-10 39.8 0.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG88564.1 - 0.0062 16.7 0.2 0.011 15.9 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG88564.1 - 0.041 14.1 2.4 0.076 13.3 2.4 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Herpes_LMP2 PF07415.11 GBG88564.1 - 0.23 10.2 1.3 0.36 9.6 1.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Herpes_UL32 PF06070.11 GBG88565.1 - 0.045 11.5 1.1 0.056 11.2 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 ZapB PF06005.12 GBG88566.1 - 0.0041 17.5 10.7 0.79 10.2 0.1 3.9 1 1 3 4 4 4 2 Cell division protein ZapB HALZ PF02183.18 GBG88566.1 - 0.048 13.9 6.0 2.6 8.3 0.1 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 GBG88566.1 - 0.1 12.4 9.6 1.7 8.4 0.3 3.4 2 1 1 3 3 3 0 Septum formation initiator betaPIX_CC PF16523.5 GBG88566.1 - 0.33 10.8 0.1 0.33 10.8 0.1 3.1 3 1 1 4 4 4 0 betaPIX coiled coil CCDC92 PF14916.6 GBG88566.1 - 0.33 10.7 1.9 2.3 8.0 0.4 2.6 2 1 0 2 2 2 0 Coiled-coil domain of unknown function Cnn_1N PF07989.11 GBG88566.1 - 0.5 10.6 5.8 0.26 11.5 1.6 2.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 GBG88566.1 - 0.67 10.4 2.7 7.6 7.0 0.5 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) PikAIV_N PF18605.1 GBG88566.1 - 0.79 9.4 7.8 0.38 10.4 3.7 2.7 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain PRKG1_interact PF15898.5 GBG88566.1 - 8.8 7.3 17.1 4.1 8.4 4.4 3.5 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain Myb_DNA-bind_4 PF13837.6 GBG88567.1 - 1.6e-09 38.0 0.1 4.1e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CDC45 PF02724.14 GBG88567.1 - 0.041 12.2 1.4 0.054 11.8 1.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-binding PF00249.31 GBG88567.1 - 0.045 13.9 1.3 0.079 13.2 0.3 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG88567.1 - 0.12 12.6 5.4 0.071 13.4 1.9 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Zip PF02535.22 GBG88567.1 - 0.13 11.4 1.3 0.17 11.0 1.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GBG88567.1 - 0.54 9.0 5.0 0.76 8.5 5.0 1.2 1 0 0 1 1 1 0 Presenilin DDE_Tnp_4 PF13359.6 GBG88569.1 - 9.8e-32 109.8 0.0 3.9e-31 107.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88569.1 - 1.2e-12 47.9 0.0 4.8e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88569.1 - 0.00012 21.8 0.1 0.84 9.2 0.0 3.4 3 0 0 3 3 3 3 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG88570.1 - 1.3e-09 38.3 0.2 2.6e-09 37.4 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG88570.1 - 0.0059 16.8 0.3 0.01 16.0 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG88570.1 - 0.03 14.6 1.9 0.055 13.7 1.9 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Mre11_DNA_bind PF04152.14 GBG88571.1 - 3.4e-32 112.1 0.0 2.2e-31 109.4 0.0 2.1 1 1 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 GBG88571.1 - 1.2e-14 55.3 0.2 1.8e-14 54.8 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SDA1 PF05285.12 GBG88572.1 - 0.037 13.5 3.7 0.044 13.2 3.7 1.1 1 0 0 1 1 1 0 SDA1 SOG2 PF10428.9 GBG88572.1 - 0.11 11.7 9.0 0.13 11.4 9.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Gti1_Pac2 PF09729.9 GBG88572.1 - 0.33 11.0 7.7 0.51 10.4 7.7 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Mucin PF01456.17 GBG88572.1 - 0.94 9.5 18.6 1.5 8.8 18.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PNISR PF15996.5 GBG88572.1 - 1.2 9.4 4.8 1.7 8.9 4.8 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF2981 PF11200.8 GBG88572.1 - 1.9 8.1 10.1 2.4 7.8 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) GREB1 PF15782.5 GBG88572.1 - 5.2 4.0 7.8 6 3.8 7.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RIFIN PF02009.16 GBG88572.1 - 5.7 6.7 9.3 7.9 6.3 9.3 1.2 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 GBG88572.1 - 7.2 5.0 11.7 9.6 4.6 11.7 1.2 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 GBG88572.1 - 7.9 5.1 11.1 12 4.5 11.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 GBG88572.1 - 8.9 5.0 8.5 12 4.6 8.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Lipoprotein_6 PF01441.19 GBG88573.1 - 0.0025 17.8 1.4 0.0025 17.8 1.4 2.3 3 0 0 3 3 3 1 Lipoprotein ETC_C1_NDUFA4 PF04800.12 GBG88573.1 - 0.038 14.2 0.1 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 ETC complex I subunit conserved region DUF3160 PF11369.8 GBG88573.1 - 0.044 12.2 0.2 0.077 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) Lipoprotein_20 PF13942.6 GBG88573.1 - 0.12 12.3 2.7 0.11 12.4 0.9 1.8 1 1 0 1 1 1 0 YfhG lipoprotein zf-CCHC PF00098.23 GBG88574.1 - 1.2e-08 34.6 1.2 2.4e-08 33.7 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG88574.1 - 0.014 15.2 2.7 0.026 14.4 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle MarC PF01914.17 GBG88574.1 - 0.27 10.6 1.3 0.5 9.7 1.3 1.3 1 0 0 1 1 1 0 MarC family integral membrane protein DDE_Tnp_4 PF13359.6 GBG88575.1 - 9.8e-28 96.8 0.0 1.4e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88575.1 - 2.9e-10 40.1 0.0 6.9e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88575.1 - 5.3e-06 26.2 0.3 0.0099 15.5 0.0 2.4 2 1 0 2 2 2 2 Transposase DDE domain Uteroglobin PF01099.17 GBG88576.1 - 0.041 14.2 0.1 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 Uteroglobin family Cytochrom_B558a PF05038.13 GBG88576.1 - 0.16 11.5 0.5 0.4 10.2 0.5 1.6 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit RT_RNaseH_2 PF17919.1 GBG88577.1 - 1.4e-26 92.4 0.0 2.7e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88577.1 - 7.2e-24 84.5 0.0 1.2e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88577.1 - 2e-23 82.7 0.0 3.8e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88577.1 - 0.00073 19.6 0.1 0.0015 18.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG88577.1 - 0.021 15.5 0.0 0.044 14.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG88577.1 - 0.043 14.4 0.0 0.083 13.5 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pox_Ag35 PF03286.14 GBG88578.1 - 0.019 14.7 12.5 0.019 14.7 12.5 3.0 3 0 0 3 3 3 0 Pox virus Ag35 surface protein SLC12 PF03522.15 GBG88578.1 - 3.8 6.4 18.7 4.6 6.1 18.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 WRNPLPNID PF15017.6 GBG88578.1 - 5.6 7.9 45.9 0.73 10.7 10.9 3.6 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box K_channel_TID PF07941.11 GBG88578.1 - 9.8 6.7 14.8 12 6.5 6.7 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain CDC45 PF02724.14 GBG88579.1 - 0.00019 19.9 18.4 0.00021 19.7 18.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Macoilin PF09726.9 GBG88579.1 - 1 7.8 14.3 1.2 7.6 14.3 1.1 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 GBG88579.1 - 1.3 7.7 9.5 1.4 7.7 9.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 GBG88579.1 - 1.8 7.5 17.0 2.8 6.9 17.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SRP-alpha_N PF04086.13 GBG88579.1 - 6.1 6.7 33.3 9.5 6.0 33.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Med19 PF10278.9 GBG88579.1 - 9.6 6.1 70.3 0.13 12.2 42.0 3.4 1 1 1 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Cu_amine_oxid PF01179.20 GBG88580.1 - 1e-133 446.2 0.0 5.2e-110 368.2 0.0 2.2 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain KELK PF15796.5 GBG88580.1 - 0.16 12.4 0.4 0.29 11.6 0.4 1.4 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DHR10 PF18595.1 GBG88580.1 - 1 9.5 4.8 2.2 8.4 3.1 2.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Cu_amine_oxidN2 PF02727.16 GBG88581.1 - 3.7e-05 23.9 0.0 0.00019 21.6 0.0 2.2 1 1 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 GBG88581.1 - 0.0041 17.5 0.0 0.05 14.0 0.0 2.4 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain YaiA PF16362.5 GBG88581.1 - 0.11 12.6 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 YaiA protein SR-25 PF10500.9 GBG88581.1 - 7.1 6.2 14.3 12 5.5 14.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 GBG88581.1 - 8.3 6.7 13.3 16 5.8 13.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Chorismate_bind PF00425.18 GBG88582.1 - 2.5e-52 178.0 0.7 5.7e-47 160.4 0.0 2.4 3 0 0 3 3 3 2 chorismate binding enzyme TPP_enzyme_N PF02776.18 GBG88582.1 - 3.4e-16 59.3 0.0 7.5e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF711 PF05167.12 GBG88582.1 - 0.0071 15.3 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) PheRS_DBD2 PF18554.1 GBG88582.1 - 0.16 12.0 0.1 0.42 10.6 0.1 1.7 1 0 0 1 1 1 0 PheRS DNA binding domain 2 TetR_C_21 PF17926.1 GBG88582.1 - 0.83 9.8 4.2 0.43 10.7 1.0 2.2 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain zf-CCHC PF00098.23 GBG88584.1 - 0.03 14.4 1.9 0.052 13.7 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG88584.1 - 0.086 12.5 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RT_RNaseH PF17917.1 GBG88585.1 - 2.4e-22 79.2 0.0 3.8e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88585.1 - 2.4e-20 72.4 0.0 4.1e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88585.1 - 4.7e-15 55.4 0.2 8.3e-15 54.6 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88585.1 - 0.047 13.9 0.0 0.19 11.9 0.0 2.0 3 0 0 3 3 3 0 Integrase core domain PaRep2a PF07903.11 GBG88585.1 - 0.094 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 PaRep2a protein MR_MLE_C PF13378.6 GBG88586.1 - 1.3e-19 70.6 0.8 3.5e-19 69.3 0.1 2.1 2 0 0 2 2 2 1 Enolase C-terminal domain-like RT_RNaseH PF17917.1 GBG88586.1 - 1.2e-13 51.2 0.0 4.1e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88586.1 - 1.4e-13 50.7 0.2 1.4e-13 50.7 0.2 2.9 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG88586.1 - 6.7e-10 38.9 0.0 1.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TPP_enzyme_M_2 PF16582.5 GBG88586.1 - 8.6e-10 38.7 0.1 1.3e-06 28.3 0.0 3.4 3 0 0 3 3 3 2 Middle domain of thiamine pyrophosphate rve PF00665.26 GBG88586.1 - 9.5e-10 38.7 0.0 4e-09 36.7 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG88586.1 - 4.2e-08 33.7 0.0 1.2e-07 32.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88586.1 - 1.7e-07 31.7 0.0 5.7e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TPP_enzyme_C PF02775.21 GBG88586.1 - 5.4e-06 26.3 0.0 2.1e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Retrotrans_gag PF03732.17 GBG88586.1 - 1.4e-05 25.2 0.3 0.9 9.9 0.0 4.2 3 0 0 3 3 3 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG88586.1 - 0.00023 20.9 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88586.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG88587.1 - 5.9e-30 104.4 0.1 9.4e-29 100.5 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88587.1 - 6.4e-27 93.5 0.0 2e-26 91.9 0.0 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88587.1 - 7.9e-24 84.0 0.0 2.2e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Abhydrolase_6 PF12697.7 GBG88587.1 - 1.2e-20 75.0 0.0 1.1e-12 49.0 0.0 4.2 3 2 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG88587.1 - 2.9e-14 53.3 0.0 6.3e-13 49.0 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Asp_protease_2 PF13650.6 GBG88587.1 - 1.1e-07 32.4 0.0 4.4e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88587.1 - 6.5e-07 29.8 0.0 1.6e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Hydrolase_4 PF12146.8 GBG88587.1 - 9e-07 28.4 0.0 6.4e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 RVP_2 PF08284.11 GBG88587.1 - 8.4e-06 25.6 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Thioesterase PF00975.20 GBG88587.1 - 0.00027 21.1 0.1 0.00075 19.7 0.1 1.7 1 0 0 1 1 1 1 Thioesterase domain Asp_protease PF09668.10 GBG88587.1 - 0.00043 20.1 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Ndr PF03096.14 GBG88587.1 - 0.0006 18.6 0.0 0.064 11.9 0.0 2.3 2 0 0 2 2 2 1 Ndr family Esterase PF00756.20 GBG88587.1 - 0.0086 15.7 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 Putative esterase Retrotrans_gag PF03732.17 GBG88587.1 - 0.044 14.1 0.0 0.21 11.9 0.0 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein Abhydrolase_2 PF02230.16 GBG88587.1 - 0.074 12.9 0.0 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 GBG88587.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Integrase_H2C2 PF17921.1 GBG88588.1 - 1.6e-14 53.7 0.1 3.9e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG88588.1 - 1.9e-07 31.0 0.0 4.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88588.1 - 1.2e-05 25.5 0.0 3.6e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88588.1 - 2.5e-05 24.4 0.0 6.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG88588.1 - 0.0032 17.7 0.0 0.0069 16.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger SlyX PF04102.12 GBG88588.1 - 0.021 15.4 0.0 0.19 12.4 0.0 2.7 1 0 0 1 1 1 0 SlyX FAM76 PF16046.5 GBG88589.1 - 5.9 6.1 17.8 2.7 7.3 15.0 1.8 1 1 1 2 2 2 0 FAM76 protein FKBP_C PF00254.28 GBG88590.1 - 1.2e-15 57.6 0.0 2.8e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NYD-SP28 PF14772.6 GBG88591.1 - 5.9e-07 29.5 11.8 5.9e-07 29.5 11.8 1.8 1 1 1 2 2 2 1 Sperm tail NYD-SP28 PF14772.6 GBG88592.1 - 4.7e-18 65.1 8.1 4.7e-18 65.1 8.1 6.5 5 1 2 7 7 7 1 Sperm tail NYD-SP28_assoc PF14775.6 GBG88592.1 - 2.3e-13 50.0 3.1 2.3e-13 50.0 3.1 4.4 4 1 3 7 7 7 1 Sperm tail C-terminal domain Zip PF02535.22 GBG88592.1 - 0.96 8.6 6.0 1.5 7.9 6.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SNF2_N PF00176.23 GBG88593.1 - 1.4e-69 234.5 0.0 2.4e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 GBG88593.1 - 2.7e-43 146.6 1.0 2.7e-43 146.6 1.0 2.9 3 0 0 3 3 3 1 SLIDE Helicase_C PF00271.31 GBG88593.1 - 3.1e-20 72.6 0.1 8.9e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG88593.1 - 9.1e-09 35.5 0.0 3.7e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HAND PF09110.11 GBG88593.1 - 8.7e-08 32.9 5.4 8.7e-08 32.9 5.4 4.6 3 1 0 3 3 3 1 HAND DEAD PF00270.29 GBG88593.1 - 1.7e-05 24.6 0.0 5.3e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GBG88593.1 - 0.0016 17.6 0.0 0.007 15.6 0.1 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 GBG88593.1 - 0.0035 17.0 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 GBG88593.1 - 0.063 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP-alpha_N PF04086.13 GBG88594.1 - 0.022 14.7 10.0 0.032 14.2 10.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Retrotrans_gag PF03732.17 GBG88594.1 - 0.067 13.5 0.1 0.19 12.0 0.0 1.7 1 1 1 2 2 2 0 Retrotransposon gag protein Totivirus_coat PF05518.11 GBG88594.1 - 9 4.2 6.2 12 3.8 6.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein Amino_oxidase PF01593.24 GBG88595.1 - 6.4e-18 65.3 0.0 1.2e-17 64.4 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG88595.1 - 2.2e-11 43.8 0.7 3.5e-10 40.0 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG88595.1 - 1.2e-08 35.0 1.7 2.4e-07 30.6 1.7 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG88595.1 - 7.3e-08 31.9 2.0 7.3e-05 22.0 0.1 3.6 4 0 0 4 4 4 2 FAD binding domain FAD_oxidored PF12831.7 GBG88595.1 - 5.8e-06 25.9 0.3 0.00063 19.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.18 GBG88595.1 - 4.5e-05 22.2 0.1 0.1 11.1 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor Pyr_redox_2 PF07992.14 GBG88595.1 - 6.9e-05 22.2 1.8 0.0016 17.8 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG88595.1 - 0.00023 20.0 0.1 0.012 14.4 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 GBG88595.1 - 0.0014 17.9 0.2 0.0027 17.0 0.2 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 GBG88595.1 - 0.0041 16.3 0.1 0.065 12.3 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GBG88595.1 - 0.0091 15.3 0.4 0.015 14.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GBG88595.1 - 0.12 12.9 0.6 21 5.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cyclin_N PF00134.23 GBG88596.1 - 1.2e-47 160.8 2.2 2.5e-47 159.8 2.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GBG88596.1 - 1.1e-32 112.7 0.3 4.3e-32 110.7 0.1 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 GBG88596.1 - 0.15 12.5 0.1 0.75 10.2 0.0 2.2 2 0 0 2 2 2 0 Cyclin C-terminal domain Nop14 PF04147.12 GBG88597.1 - 0.056 11.7 6.9 0.064 11.5 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family LTV PF04180.14 GBG88597.1 - 0.17 11.6 6.9 0.24 11.1 6.9 1.1 1 0 0 1 1 1 0 Low temperature viability protein Lin-8 PF03353.15 GBG88597.1 - 0.17 11.4 4.6 0.24 10.9 4.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 GBG88597.1 - 0.32 9.2 8.2 0.4 8.9 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG88597.1 - 0.98 8.8 9.9 1.3 8.4 9.9 1.1 1 0 0 1 1 1 0 SDA1 SIR4_SID PF16991.5 GBG88597.1 - 1.1 9.3 3.8 1.7 8.7 3.8 1.2 1 0 0 1 1 1 0 Sir4 SID domain Myb_DNA-bind_4 PF13837.6 GBG88598.1 - 4.9e-09 36.5 6.0 6.8e-09 36.0 3.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG88598.1 - 0.0046 17.3 2.5 0.0048 17.2 1.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like CDC50 PF03381.15 GBG88599.1 - 1.8e-71 241.0 0.0 2.3e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF2157 PF09925.9 GBG88599.1 - 0.023 14.5 0.2 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) SSP160 PF06933.11 GBG88599.1 - 0.85 7.7 5.9 1.1 7.4 5.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SnoaL_3 PF13474.6 GBG88601.1 - 5.7e-23 81.5 0.2 1.1e-22 80.6 0.2 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 GBG88601.1 - 7e-05 23.2 0.1 0.0011 19.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) F-box-like PF12937.7 GBG88601.1 - 0.00039 20.2 0.2 0.0018 18.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like SnoaL_2 PF12680.7 GBG88601.1 - 0.0039 17.8 2.4 0.19 12.4 0.3 2.5 1 1 1 2 2 2 2 SnoaL-like domain F-box PF00646.33 GBG88601.1 - 0.013 15.4 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain CaMKII_AD PF08332.10 GBG88601.1 - 0.12 12.5 0.3 0.31 11.2 0.3 1.7 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain Metallophos PF00149.28 GBG88602.1 - 2.5e-10 41.2 0.2 3.6e-10 40.7 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ferric_reduct PF01794.19 GBG88602.1 - 0.094 12.8 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Ferric reductase like transmembrane component SPC12 PF06645.13 GBG88603.1 - 2.4e-26 91.6 0.4 2.9e-26 91.4 0.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) dCache_3 PF14827.6 GBG88604.1 - 0.1 12.2 1.7 0.15 11.7 0.2 1.9 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase IER PF05760.12 GBG88604.1 - 0.16 12.2 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Myb_DNA-bind_4 PF13837.6 GBG88605.1 - 3.1e-09 37.1 0.1 8.4e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG88605.1 - 0.0034 17.5 0.2 0.009 16.2 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG88605.1 - 0.12 12.6 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Asp_protease_2 PF13650.6 GBG88606.1 - 7.2e-06 26.6 0.0 1.6e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG88606.1 - 1.4e-05 24.8 0.1 2.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG88606.1 - 3.7e-05 24.2 0.0 8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88606.1 - 0.0006 19.6 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG88606.1 - 0.00077 19.7 0.2 0.0027 17.9 0.1 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG88606.1 - 0.0023 17.7 0.0 0.0063 16.3 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG88607.1 - 1.3e-09 38.0 0.3 3.1e-09 36.8 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88607.1 - 2.4e-07 31.0 0.0 4.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF5536 PF17688.1 GBG88607.1 - 0.74 9.7 2.5 1.4 8.8 2.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5536) DUF4604 PF15377.6 GBG88607.1 - 0.81 10.1 6.4 0.42 11.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Ephrin_rec_like PF07699.13 GBG88608.1 - 0.00011 21.9 1.2 0.00029 20.6 1.2 1.8 1 0 0 1 1 1 1 Putative ephrin-receptor like NCD3G PF07562.14 GBG88608.1 - 0.19 11.7 1.1 0.58 10.2 1.1 1.9 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Toxin_38 PF14866.6 GBG88610.1 - 0.21 11.9 4.7 3.5 8.0 0.6 2.2 1 1 1 2 2 2 0 Potassium channel toxin DUF659 PF04937.15 GBG88611.1 - 3.5e-21 75.7 0.0 5.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88611.1 - 1.6e-06 27.8 0.1 3.2e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF594 PF04578.13 GBG88611.1 - 0.02 14.5 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF594 DUF687 PF05095.12 GBG88611.1 - 4.5 5.7 4.8 0.47 8.9 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF687) RVT_1 PF00078.27 GBG88613.1 - 6.2e-26 91.3 0.1 9.8e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG88613.1 - 0.12 12.4 0.0 7.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L34 GHMP_kinases_C PF08544.13 GBG88613.1 - 0.14 12.5 0.0 6 7.3 0.0 2.3 2 0 0 2 2 2 0 GHMP kinases C terminal Cyt-b5 PF00173.28 GBG88614.1 - 1.3e-19 70.1 0.0 2.4e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ion_trans PF00520.31 GBG88614.1 - 4.2e-10 39.3 11.3 6.3e-10 38.7 11.3 1.2 1 0 0 1 1 1 1 Ion transport protein Globin PF00042.22 GBG88614.1 - 1.1e-08 35.6 0.0 4.3e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Globin PKD_channel PF08016.12 GBG88614.1 - 0.00056 18.7 9.3 0.00087 18.1 9.3 1.2 1 0 0 1 1 1 1 Polycystin cation channel INTS2 PF14750.6 GBG88614.1 - 0.038 11.6 0.4 0.059 10.9 0.4 1.2 1 0 0 1 1 1 0 Integrator complex subunit 2 TpcC PF12642.7 GBG88615.1 - 0.02 14.7 0.3 4.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Conjugative transposon protein TcpC HHH_5 PF14520.6 GBG88615.1 - 0.16 12.6 0.0 43 4.8 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain MAGE_N PF12440.8 GBG88615.1 - 0.43 11.3 14.4 2.7 8.7 2.8 2.5 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Rib_recp_KP_reg PF05104.12 GBG88615.1 - 1 10.4 14.8 4.5 8.3 2.8 2.3 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region DUF4171 PF13775.6 GBG88615.1 - 4.7 7.7 15.1 8.2 6.9 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) DUF2950 PF11453.8 GBG88616.1 - 0.26 10.5 8.3 0.32 10.1 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) DUF3138 PF11336.8 GBG88616.1 - 0.52 8.9 2.2 0.37 9.3 0.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF2894 PF11445.8 GBG88616.1 - 8.6 6.8 14.3 21 5.5 14.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) DUF3629 PF12302.8 GBG88616.1 - 8.9 5.7 16.6 0.27 10.6 9.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3629) RT_RNaseH_2 PF17919.1 GBG88618.1 - 5e-25 87.4 0.0 8.4e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88618.1 - 1.8e-22 79.6 0.0 3.5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88618.1 - 1.3e-14 54.3 0.0 1.9e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC27 PF09507.10 GBG88623.1 - 5.2 6.4 31.0 0.0058 16.1 18.5 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF3987 PF13148.6 GBG88624.1 - 0.28 10.1 13.2 0.32 9.9 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PGA2 PF07543.12 GBG88624.1 - 0.29 11.1 17.1 0.35 10.9 17.1 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Nop25 PF09805.9 GBG88624.1 - 0.86 10.1 22.1 1.1 9.8 22.1 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Folliculin PF11704.8 GBG88624.1 - 1.9 8.3 6.0 2.7 7.9 6.0 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF2052 PF09747.9 GBG88624.1 - 2.4 8.3 18.6 2.9 8.0 18.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4407 PF14362.6 GBG88624.1 - 3.3 7.0 7.8 3.5 6.9 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.8 GBG88624.1 - 3.3 6.5 19.0 3.5 6.4 19.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM60A PF15396.6 GBG88624.1 - 4.7 7.1 11.6 5.7 6.9 11.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Het-C PF07217.11 GBG88624.1 - 6.1 5.2 8.1 7.4 5.0 8.1 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C RR_TM4-6 PF06459.12 GBG88624.1 - 7.3 6.3 20.4 8.9 6.1 20.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 GBG88624.1 - 8.2 6.1 12.0 10 5.8 12.0 1.1 1 0 0 1 1 1 0 AAA domain Membralin PF09746.9 GBG88624.1 - 9.4 5.2 5.8 10 5.0 5.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein LPP PF04728.13 GBG88625.1 - 0.0025 18.1 8.5 0.98 9.9 0.3 4.1 4 0 0 4 4 4 2 Lipoprotein leucine-zipper zf-CCHC PF00098.23 GBG88625.1 - 0.0042 17.1 5.5 0.0073 16.3 5.5 1.4 1 0 0 1 1 1 1 Zinc knuckle HsbA PF12296.8 GBG88625.1 - 0.033 14.6 0.2 0.064 13.7 0.2 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Sulfotransfer_1 PF00685.27 GBG88625.1 - 0.52 9.8 4.0 1.1 8.7 4.0 1.5 1 0 0 1 1 1 0 Sulfotransferase domain DUF1943 PF09172.11 GBG88625.1 - 1.8 7.7 8.2 3.1 7.0 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Fzo_mitofusin PF04799.13 GBG88625.1 - 2.9 7.4 10.2 0.21 11.1 0.5 3.0 2 1 1 3 3 3 0 fzo-like conserved region zf-CCHC_4 PF14392.6 GBG88625.1 - 2.9 7.7 4.4 5.6 6.8 4.4 1.5 1 0 0 1 1 1 0 Zinc knuckle HSP70 PF00012.20 GBG88625.1 - 6.6 4.8 23.7 1.6 6.8 0.8 2.2 2 0 0 2 2 2 0 Hsp70 protein DNA_pol3_delta2 PF13177.6 GBG88626.1 - 1.1e-20 74.1 0.0 2.6e-19 69.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 GBG88626.1 - 0.00061 20.2 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG88626.1 - 0.038 14.4 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 GBG88626.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SOUL PF04832.12 GBG88627.1 - 2.2e-34 119.0 0.0 2.7e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein DUF659 PF04937.15 GBG88628.1 - 3.6e-07 30.2 0.0 6.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 GBG88628.1 - 0.017 15.2 1.6 0.05 13.6 1.6 1.9 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.6 GBG88628.1 - 0.72 10.8 0.2 0.72 10.8 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger SOUL PF04832.12 GBG88629.1 - 7.7e-39 133.6 0.0 9e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein YabP PF07873.11 GBG88629.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 YabP family DUF16 PF01519.16 GBG88630.1 - 0.38 11.3 13.4 0.99 9.9 2.0 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 Sec5 PF15469.6 GBG88630.1 - 4.6 7.0 15.3 1.9 8.2 3.7 3.0 2 2 0 2 2 2 0 Exocyst complex component Sec5 Pox_A_type_inc PF04508.12 GBG88630.1 - 6 6.9 14.6 2.8 7.9 1.5 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat zf-CCHC PF00098.23 GBG88633.1 - 0.00061 19.8 2.2 0.0016 18.5 2.2 1.8 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG88633.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Methyltransf_8 PF05148.15 GBG88634.1 - 0.0018 18.2 0.1 0.0022 17.9 0.1 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase DUF4279 PF14106.6 GBG88634.1 - 0.037 14.2 0.1 0.05 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) Rsm22 PF09243.10 GBG88634.1 - 0.19 11.0 0.1 0.25 10.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Mito_carr PF00153.27 GBG88635.1 - 7.1e-50 166.9 0.6 3.6e-22 78.1 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein LANC_like PF05147.13 GBG88635.1 - 0.15 10.6 0.4 0.28 9.7 0.4 1.4 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein RT_RNaseH_2 PF17919.1 GBG88636.1 - 4.6e-23 81.1 0.0 8.4e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88636.1 - 3.8e-21 75.3 0.0 6.6e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88636.1 - 2e-17 63.0 1.8 4.8e-16 58.6 0.5 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG88636.1 - 1.8e-11 44.3 0.0 1.1e-10 41.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG88636.1 - 6.2e-10 39.0 0.2 1.1e-09 38.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG88636.1 - 0.0024 18.1 0.3 0.0063 16.7 0.3 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Integrin_b_cyt PF08725.11 GBG88636.1 - 0.093 12.4 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain APG17 PF04108.12 GBG88636.1 - 0.16 11.0 0.0 2.9 6.9 0.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF3598 PF12204.8 GBG88637.1 - 8.6e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3598) BT1 PF03092.16 GBG88639.1 - 2.5e-56 191.0 1.7 2.3e-55 187.8 1.7 2.1 1 1 0 1 1 1 1 BT1 family RT_RNaseH PF17917.1 GBG88641.1 - 7.1e-22 77.7 0.0 1.3e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88641.1 - 4.7e-21 74.7 0.0 7.9e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88641.1 - 1.1e-11 44.7 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG88641.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 Integrin_b_cyt PF08725.11 GBG88641.1 - 0.08 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain TadF PF16964.5 GBG88642.1 - 1.5 8.6 4.7 2.9 7.6 4.7 1.5 1 0 0 1 1 1 0 Putative tight adherence pilin protein F RVT_1 PF00078.27 GBG88643.1 - 1.8e-58 197.7 0.3 1.3e-28 100.1 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88643.1 - 4.9e-23 81.4 0.2 1.6e-22 79.8 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88643.1 - 2.1e-17 63.0 0.1 8.5e-17 61.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88643.1 - 1.7e-15 56.8 0.1 4.1e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88643.1 - 0.03 14.6 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger VraX PF17412.2 GBG88644.1 - 0.049 13.3 0.4 0.088 12.5 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function AcylCoA_dehyd_C PF12186.8 GBG88644.1 - 0.085 13.0 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal YabA PF06156.13 GBG88644.1 - 0.095 13.3 0.2 0.4 11.3 0.0 1.9 2 0 0 2 2 2 0 Initiation control protein YabA Ferritin PF00210.24 GBG88644.1 - 0.11 12.5 2.6 6.6 6.7 0.2 2.2 1 1 1 2 2 2 0 Ferritin-like domain GCN5L1 PF06320.13 GBG88644.1 - 1.9 8.7 8.1 0.23 11.6 3.3 1.9 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) FUSC PF04632.12 GBG88644.1 - 2.3 6.7 6.5 3.7 6.0 6.5 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family SRP54 PF00448.22 GBG88646.1 - 2.1e-74 249.4 0.2 2.8e-74 249.0 0.2 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 GBG88646.1 - 8.1e-16 58.0 1.0 1.2e-15 57.4 0.3 1.7 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 GBG88646.1 - 2e-06 27.8 1.5 2.6e-06 27.5 0.4 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 GBG88646.1 - 1.5e-05 25.3 0.0 4.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 GBG88646.1 - 3.6e-05 23.8 1.1 0.0001 22.3 0.7 1.7 1 1 1 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 GBG88646.1 - 3.8e-05 23.0 0.3 8e-05 22.0 0.3 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase Zeta_toxin PF06414.12 GBG88646.1 - 0.0014 18.0 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.19 GBG88646.1 - 0.0016 18.1 0.9 0.0031 17.1 0.9 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 GBG88646.1 - 0.0035 16.4 0.1 0.014 14.4 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 GBG88646.1 - 0.0065 17.0 0.8 0.014 16.0 0.8 1.7 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 GBG88646.1 - 0.0066 15.9 0.6 0.015 14.8 0.4 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_24 PF13479.6 GBG88646.1 - 0.0075 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG88646.1 - 0.014 15.1 0.5 0.031 14.0 0.4 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GBG88646.1 - 0.015 15.2 2.1 0.045 13.7 0.3 2.2 2 0 0 2 2 2 0 NTPase CLP1_P PF16575.5 GBG88646.1 - 0.02 14.7 0.4 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRPRB PF09439.10 GBG88646.1 - 0.032 13.6 0.7 4.7 6.6 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 GBG88646.1 - 0.061 13.1 0.4 0.096 12.5 0.4 1.5 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 GBG88646.1 - 0.073 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 GBG88646.1 - 0.077 13.1 1.8 0.5 10.5 1.1 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATPase PF06745.13 GBG88646.1 - 0.085 12.2 0.2 0.15 11.3 0.2 1.5 1 1 0 1 1 1 0 KaiC AAA_16 PF13191.6 GBG88646.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 GBG88646.1 - 0.18 11.4 2.3 2.5 7.6 2.3 2.3 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 GBG88646.1 - 0.19 11.4 1.5 8.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RVT_1 PF00078.27 GBG88647.1 - 2.8e-31 108.8 0.0 9e-31 107.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88647.1 - 2.6e-22 78.7 0.0 6.6e-22 77.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88647.1 - 2.9e-22 78.9 0.0 7.4e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88647.1 - 4.6e-20 71.5 0.1 1.2e-19 70.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG88647.1 - 7.8e-10 38.7 0.0 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88647.1 - 1.7e-08 35.0 0.0 4.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88647.1 - 2.6e-06 27.9 0.0 6.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88647.1 - 0.0007 19.4 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG88647.1 - 0.0041 17.4 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein CorA PF01544.18 GBG88647.1 - 0.024 14.0 2.4 0.043 13.1 0.5 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein zf-H2C2 PF09337.10 GBG88647.1 - 0.087 13.1 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger SRP_SPB PF02978.19 GBG88648.1 - 2.4e-28 98.7 7.5 2.4e-28 98.7 7.5 2.7 2 1 1 3 3 3 1 Signal peptide binding domain DUF4239 PF14023.6 GBG88648.1 - 0.083 12.6 1.0 3.3 7.4 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) ACP_PD PF04336.12 GBG88648.1 - 3.1 8.3 4.9 8.1 6.9 0.4 3.0 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase RVT_1 PF00078.27 GBG88649.1 - 3.7e-30 105.1 0.1 9e-30 103.8 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88649.1 - 3.7e-16 59.0 0.0 1.2e-15 57.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88649.1 - 7.8e-10 39.0 0.0 1.8e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG88649.1 - 9.7e-09 35.8 0.0 3.3e-08 34.0 0.0 1.9 2 0 0 2 2 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88649.1 - 7.6e-08 32.2 0.0 2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88649.1 - 5.6e-07 30.0 0.0 1.8e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88649.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG88649.1 - 0.011 16.1 0.0 0.29 11.5 0.0 2.8 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Retrotrans_gag PF03732.17 GBG88649.1 - 0.047 14.0 1.5 0.24 11.7 0.0 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein JIP_LZII PF16471.5 GBG88649.1 - 1.7 8.9 6.7 0.58 10.4 2.6 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II FAM76 PF16046.5 GBG88649.1 - 10 5.4 6.7 16 4.8 6.7 1.3 1 0 0 1 1 1 0 FAM76 protein DUF659 PF04937.15 GBG88652.1 - 3.3e-18 66.0 0.0 5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88653.1 - 5.5e-09 35.7 0.1 1.4e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PadR PF03551.14 GBG88653.1 - 0.15 12.1 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family AT_hook PF02178.19 GBG88653.1 - 1.1 9.3 15.6 0.37 10.8 2.6 3.1 2 0 0 2 2 2 0 AT hook motif Troponin-I_N PF11636.8 GBG88653.1 - 1.8 8.6 7.9 4.3 7.4 4.9 3.0 2 0 0 2 2 2 0 Troponin I residues 1-32 DUF3007 PF11460.8 GBG88655.1 - 7.7e-32 109.4 0.4 1e-31 109.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) DUF659 PF04937.15 GBG88656.1 - 7.3e-10 38.9 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88656.1 - 2.2e-05 24.2 0.4 5.3e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3156 PF11354.8 GBG88657.1 - 0.0015 18.5 0.5 0.0043 17.0 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3156) Sec2p PF06428.11 GBG88657.1 - 0.0032 17.4 1.5 0.013 15.4 1.5 2.1 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Allexi_40kDa PF05549.11 GBG88657.1 - 0.029 13.9 2.6 0.053 13.0 1.3 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein Fib_alpha PF08702.10 GBG88657.1 - 0.85 9.8 6.4 2.1 8.5 3.9 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TACC_C PF05010.14 GBG88657.1 - 1.6 8.5 11.1 3.6 7.3 4.7 2.8 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAT PF03127.14 GBG88657.1 - 4.1 7.8 5.0 21 5.5 0.1 3.3 3 0 0 3 3 3 0 GAT domain DUF4057 PF13266.6 GBG88658.1 - 2.7e-36 125.8 0.2 2.7e-36 125.8 0.2 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF4057) TPR_1 PF00515.28 GBG88659.1 - 1.1e-25 88.3 15.1 5.9e-06 25.9 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 GBG88659.1 - 2.1e-23 80.5 16.9 3.9e-05 23.4 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 GBG88659.1 - 6.5e-14 51.3 12.0 8.3e-06 25.4 0.2 4.0 4 0 0 4 4 4 3 TPR repeat TPR_8 PF13181.6 GBG88659.1 - 1.7e-11 43.3 11.8 0.012 15.7 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 GBG88659.1 - 8.8e-09 35.9 17.5 3e-06 27.8 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG88659.1 - 1.6e-06 28.3 23.2 0.57 10.5 0.9 6.6 6 1 1 7 7 6 4 Tetratricopeptide repeat CS PF04969.16 GBG88659.1 - 9.3e-06 26.6 0.2 2.4e-05 25.3 0.2 1.7 1 0 0 1 1 1 1 CS domain TPR_14 PF13428.6 GBG88659.1 - 1.3e-05 25.6 12.5 0.043 14.7 0.0 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 GBG88659.1 - 0.00013 22.1 1.5 0.2 12.1 0.2 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 GBG88659.1 - 0.00013 21.8 4.7 0.26 11.0 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 GBG88659.1 - 0.00023 21.3 18.7 0.19 11.9 0.1 5.6 4 2 2 6 6 6 2 Tetratricopeptide repeat TFIIF_alpha PF05793.12 GBG88659.1 - 0.0029 16.3 14.9 0.0029 16.3 14.9 4.2 3 1 1 4 4 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPR_7 PF13176.6 GBG88659.1 - 0.015 15.3 16.2 0.83 9.8 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG88659.1 - 0.036 14.6 14.8 0.053 14.0 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 GBG88659.1 - 0.1 11.8 0.0 0.1 11.8 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GBG88659.1 - 0.51 10.3 10.4 17 5.4 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG88659.1 - 0.53 10.5 5.8 0.32 11.3 0.3 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 HMA PF00403.26 GBG88660.1 - 1.7e-11 44.4 0.3 3.2e-11 43.5 0.3 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain RVT_1 PF00078.27 GBG88662.1 - 3e-20 72.7 0.1 4.7e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG88662.1 - 1.9e-06 27.7 0.0 3.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88662.1 - 5.6e-06 26.8 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88662.1 - 6.5e-06 26.7 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88662.1 - 8e-06 25.7 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease cNMP_binding PF00027.29 GBG88663.1 - 3.3e-42 142.5 0.0 4.5e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain NDUF_B4 PF07225.12 GBG88663.1 - 0.092 12.7 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Glyco_transf_29 PF00777.18 GBG88664.1 - 7e-36 124.0 1.7 3.8e-34 118.3 1.7 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) EGF_Tenascin PF18720.1 GBG88664.1 - 0.85 9.7 2.9 1.9 8.6 2.9 1.6 1 0 0 1 1 1 0 Tenascin EGF domain His_Phos_2 PF00328.22 GBG88665.1 - 4.1e-19 69.2 0.0 1.7e-08 34.3 0.0 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) HEXIM PF15313.6 GBG88666.1 - 0.035 14.3 1.7 0.048 13.8 1.7 1.1 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein Histone PF00125.24 GBG88667.1 - 0.55 10.6 6.2 0.61 10.4 6.2 1.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CDC27 PF09507.10 GBG88667.1 - 1.1 8.5 13.1 1.3 8.4 13.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 GBG88667.1 - 2.5 6.3 15.1 2.7 6.2 15.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DLEU7 PF15760.5 GBG88667.1 - 3.3 7.2 5.9 4.1 6.8 5.9 1.3 1 0 0 1 1 1 0 Leukemia-associated protein 7 RR_TM4-6 PF06459.12 GBG88667.1 - 5.8 6.6 7.6 6.9 6.4 7.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVT_1 PF00078.27 GBG88668.1 - 1.3e-29 103.3 0.0 2.2e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG88668.1 - 3.3e-05 23.7 0.0 7.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG88669.1 - 9.7e-05 22.6 4.9 0.0002 21.5 0.0 3.4 3 1 0 3 3 3 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG88669.1 - 0.016 15.7 1.2 0.29 11.6 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ric8 PF10165.9 GBG88669.1 - 0.022 13.8 0.7 0.031 13.3 0.7 1.3 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn GIY-YIG PF01541.24 GBG88672.1 - 0.0034 17.6 0.0 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 GIY-YIG catalytic domain RVT_1 PF00078.27 GBG88672.1 - 0.011 15.3 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) YdaS_antitoxin PF15943.5 GBG88672.1 - 0.15 12.0 0.1 0.82 9.6 0.1 2.3 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PPR PF01535.20 GBG88673.1 - 6.7e-113 361.4 51.3 1.5e-08 34.3 0.0 18.7 19 0 0 19 19 19 17 PPR repeat PPR_2 PF13041.6 GBG88673.1 - 8.5e-105 342.8 30.1 3.9e-13 49.4 0.0 16.4 5 5 13 18 18 18 16 PPR repeat family PPR_1 PF12854.7 GBG88673.1 - 1.3e-101 332.0 11.1 1e-10 41.1 0.0 17.3 18 0 0 18 18 18 14 PPR repeat PPR_3 PF13812.6 GBG88673.1 - 3.1e-74 245.0 1.6 9.8e-13 48.0 0.0 12.0 8 3 5 13 13 13 10 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG88673.1 - 1.4e-48 165.1 1.2 3.6e-11 42.8 0.0 6.6 1 1 6 8 8 8 7 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG88673.1 - 1.7e-11 44.5 5.3 0.22 12.0 0.0 7.5 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG88673.1 - 2.3e-11 43.5 4.1 5.7 8.0 0.0 11.3 10 2 3 13 13 12 1 Tetratricopeptide repeat TPR_4 PF07721.14 GBG88673.1 - 8e-07 29.1 3.8 4.9 8.1 0.0 8.4 9 0 0 9 9 7 1 Tetratricopeptide repeat RPN7 PF10602.9 GBG88673.1 - 5.3e-06 26.2 3.2 0.29 10.8 0.0 5.2 3 2 0 4 4 4 2 26S proteasome subunit RPN7 ECSIT PF06239.11 GBG88673.1 - 2.7e-05 23.4 2.5 4.4 6.4 0.0 5.6 4 1 2 6 6 6 2 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.6 GBG88673.1 - 0.00046 20.4 9.8 7.7 6.9 0.0 8.3 8 2 1 9 9 9 1 Tetratricopeptide repeat Clathrin PF00637.20 GBG88673.1 - 0.00068 19.5 0.3 7.7 6.4 0.0 5.7 4 2 2 6 6 6 1 Region in Clathrin and VPS TPR_7 PF13176.6 GBG88673.1 - 0.00084 19.2 0.1 34 4.8 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat PYRIN PF02758.16 GBG88673.1 - 0.004 17.3 0.8 3 8.1 0.0 4.4 4 0 0 4 4 4 1 PAAD/DAPIN/Pyrin domain TPR_1 PF00515.28 GBG88673.1 - 0.0044 16.8 5.1 13 5.8 0.0 7.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG88673.1 - 0.0062 17.2 3.2 20 5.9 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 GBG88673.1 - 0.11 13.0 3.0 8.1 6.9 0.0 3.7 4 0 0 4 4 3 0 Bacterial transcriptional activator domain AEP1 PF17049.5 GBG88673.1 - 0.14 11.2 0.0 50 2.8 0.0 4.1 4 0 0 4 4 4 0 ATPase expression protein 1 MRP-S27 PF10037.9 GBG88673.1 - 0.16 10.8 0.1 3.5 6.4 0.1 2.8 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_10 PF13374.6 GBG88673.1 - 0.45 10.5 16.7 10 6.2 0.1 7.5 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 GBG88673.1 - 6.7 7.1 12.3 40 4.7 0.1 7.0 9 0 0 9 9 7 0 Tetratricopeptide repeat Sec3_C PF09763.9 GBG88674.1 - 4.5e-102 342.7 1.8 2.5e-100 336.9 1.8 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 GBG88674.1 - 3.6e-09 36.6 0.0 8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 GBG88674.1 - 1.2e-08 34.2 1.2 1.2e-08 34.2 1.2 2.5 2 1 0 2 2 2 1 Vps52 / Sac2 family CENP-F_leu_zip PF10473.9 GBG88674.1 - 0.025 14.6 4.1 0.069 13.2 4.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoLp-III PF07464.11 GBG88674.1 - 0.027 14.5 0.1 0.39 10.8 0.0 3.0 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Spidroin_N PF16763.5 GBG88674.1 - 0.068 13.2 2.5 1.6 8.8 0.1 3.4 3 0 0 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term FliD_N PF02465.18 GBG88674.1 - 0.8 10.4 4.2 96 3.8 0.1 3.7 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus SBF_like PF13593.6 GBG88675.1 - 7e-44 150.4 9.9 7.9e-34 117.4 12.0 2.1 2 0 0 2 2 2 2 SBF-like CPA transporter family (DUF4137) Integrase_H2C2 PF17921.1 GBG88675.1 - 7.1e-20 70.9 0.2 1.6e-19 69.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain SBF PF01758.16 GBG88675.1 - 1e-11 44.9 9.7 1.7e-11 44.1 9.7 1.2 1 0 0 1 1 1 1 Sodium Bile acid symporter family rve PF00665.26 GBG88675.1 - 1.2e-08 35.2 0.0 2.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG88675.1 - 0.017 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Laminin_G_3 PF13385.6 GBG88676.1 - 1.1e-09 38.6 0.2 2.5e-08 34.2 0.2 2.9 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF4392 PF14336.6 GBG88676.1 - 0.07 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) BRE1 PF08647.11 GBG88677.1 - 2.1e-11 43.7 0.8 2.1e-11 43.7 0.8 8.7 5 2 2 9 9 9 2 BRE1 E3 ubiquitin ligase Thioredoxin PF00085.20 GBG88678.1 - 2.3e-15 56.5 0.0 3.9e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin ERp29 PF07749.12 GBG88678.1 - 6.2e-15 55.9 0.1 9.7e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 GBG88678.1 - 0.00055 19.4 0.0 0.00079 18.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GBG88678.1 - 0.098 13.1 1.2 0.48 10.9 0.1 2.7 3 1 0 3 3 3 0 Thioredoxin-like domain RT_RNaseH_2 PF17919.1 GBG88679.1 - 1.1e-24 86.4 0.0 1.6e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88679.1 - 1.4e-20 73.6 0.0 2.3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG88679.1 - 0.13 10.4 7.4 0.17 10.1 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG88679.1 - 1.2 7.4 9.8 1.6 6.9 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG88679.1 - 1.4 8.3 10.7 1.8 7.9 10.7 1.1 1 0 0 1 1 1 0 SDA1 PV-1 PF06637.11 GBG88680.1 - 0.32 9.8 9.6 0.46 9.3 9.6 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PBP_sp32 PF07222.12 GBG88680.1 - 6 6.2 9.2 11 5.4 9.2 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 HATPase_c PF02518.26 GBG88681.1 - 1.7e-22 80.0 0.1 4e-17 62.7 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PIF1 PF05970.14 GBG88681.1 - 1.8e-06 27.4 0.0 2.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase HATPase_c PF02518.26 GBG88682.1 - 1.7e-22 80.0 0.1 4e-17 62.7 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PIF1 PF05970.14 GBG88682.1 - 1.8e-06 27.4 0.0 2.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Retrotrans_gag PF03732.17 GBG88683.1 - 0.0019 18.4 0.1 0.0079 16.4 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein SlyX PF04102.12 GBG88683.1 - 0.014 15.9 0.9 0.014 15.9 0.9 3.1 3 1 1 4 4 4 0 SlyX DXP_reductoisom PF02670.16 GBG88683.1 - 0.038 14.7 0.4 2.6 8.8 0.0 3.3 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TolA_bind_tri PF16331.5 GBG88683.1 - 3.4 7.8 10.9 0.18 11.9 3.2 2.8 3 1 1 4 4 4 0 TolA binding protein trimerisation FTHFS PF01268.19 GBG88684.1 - 3.5 5.7 7.0 0.33 9.1 2.4 1.5 2 0 0 2 2 2 0 Formate--tetrahydrofolate ligase DUF4800 PF16057.5 GBG88684.1 - 5.3 6.2 13.8 6 6.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) SMYLE_N PF18615.1 GBG88685.1 - 0.039 13.5 0.9 0.055 13.0 0.9 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SAM_1 PF00536.30 GBG88686.1 - 2.3e-17 63.2 0.0 3.7e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GBG88686.1 - 1.9e-10 40.7 0.0 4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GBG88687.1 - 1.9e-17 63.4 0.0 3.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GBG88687.1 - 1.1e-10 41.5 0.0 2.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SDA1 PF05285.12 GBG88688.1 - 0.46 9.9 23.8 0.51 9.7 23.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG88688.1 - 1.2 7.3 21.8 1.2 7.3 21.8 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG88688.1 - 1.8 7.2 8.6 1.8 7.2 8.6 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 GBG88688.1 - 4.6 5.2 5.6 4.3 5.4 5.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 GBG88688.1 - 4.8 5.3 22.0 5.6 5.1 22.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 GBG88688.1 - 7.3 5.7 6.4 7 5.8 6.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Vps51 PF08700.11 GBG88690.1 - 3.3e-22 78.3 0.1 7.6e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 GBG88690.1 - 5.5e-11 42.6 0.1 9.8e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 GBG88690.1 - 5.9e-08 31.8 0.4 1.1e-07 30.9 0.4 1.3 1 0 0 1 1 1 1 Dor1-like family COG2 PF06148.11 GBG88690.1 - 7.8e-06 26.0 0.4 2.2e-05 24.5 0.4 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 GBG88690.1 - 0.00074 19.7 0.3 0.0024 18.1 0.3 1.9 1 0 0 1 1 1 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.9 GBG88690.1 - 0.14 12.2 4.5 0.1 12.6 1.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DOMON PF03351.17 GBG88691.1 - 6.1e-36 123.4 0.6 4.6e-18 65.6 0.0 3.1 2 1 0 2 2 2 2 DOMON domain DM13 PF10517.9 GBG88691.1 - 2.5e-09 37.7 0.0 5.6e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Electron transfer DM13 Cytochrom_B561 PF03188.16 GBG88691.1 - 0.004 17.3 0.2 0.0079 16.3 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 SdpI PF13630.6 GBG88691.1 - 0.0067 16.5 0.2 0.0067 16.5 0.2 1.8 2 0 0 2 2 2 1 SdpI/YhfL protein family DOMON PF03351.17 GBG88692.1 - 5e-27 94.6 0.5 2.5e-14 53.6 0.1 3.0 2 1 0 2 2 2 2 DOMON domain DM13 PF10517.9 GBG88692.1 - 3.9e-09 37.0 0.0 1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 Electron transfer DM13 SdpI PF13630.6 GBG88692.1 - 0.0042 17.2 0.2 0.012 15.8 0.2 1.8 1 0 0 1 1 1 1 SdpI/YhfL protein family Cytochrom_B561 PF03188.16 GBG88692.1 - 0.0075 16.4 0.2 0.015 15.5 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Adaptin_N PF01602.20 GBG88693.1 - 2.3e-73 247.5 2.7 9.2e-70 235.7 3.2 2.2 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 GBG88693.1 - 6.6e-37 127.0 0.3 1.1e-35 123.1 0.1 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 GBG88693.1 - 3.2e-15 56.2 0.0 6.2e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 GBG88693.1 - 2.6e-05 24.5 0.2 0.15 12.5 0.0 3.1 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 GBG88693.1 - 0.00014 21.9 0.1 1.3 9.4 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat MOR2-PAG1_C PF14225.6 GBG88693.1 - 0.024 14.5 0.9 0.051 13.4 0.9 1.5 1 0 0 1 1 1 0 Cell morphogenesis C-terminal zf-CCHC PF00098.23 GBG88694.1 - 0.0025 17.8 5.0 0.0042 17.1 5.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG88694.1 - 0.011 15.5 1.3 0.011 15.5 1.3 2.3 2 0 0 2 2 2 0 Zinc knuckle Atg14 PF10186.9 GBG88694.1 - 0.057 12.5 13.5 0.078 12.0 13.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-CCHC_4 PF14392.6 GBG88694.1 - 0.16 11.7 1.2 0.32 10.7 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle XRN_M PF17846.1 GBG88694.1 - 0.85 8.5 9.6 1.2 8.0 9.6 1.4 1 0 0 1 1 1 0 Xrn1 helical domain DUF659 PF04937.15 GBG88695.1 - 5.5e-20 71.8 0.1 3.4e-15 56.2 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88695.1 - 0.00015 21.5 0.3 0.00015 21.5 0.3 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region F-box-like PF12937.7 GBG88696.1 - 1.4e-08 34.4 3.7 4.3e-08 32.9 3.7 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG88696.1 - 1.3e-06 28.2 2.1 3.5e-06 26.8 2.1 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 GBG88696.1 - 0.001 19.4 0.4 12 6.5 0.1 4.3 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG88696.1 - 0.028 14.9 3.9 4.1 8.3 0.1 3.6 4 0 0 4 4 3 0 Leucine Rich Repeat CENP-B_dimeris PF09026.10 GBG88696.1 - 0.058 13.8 8.5 0.1 13.0 8.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 GBG88696.1 - 0.09 12.6 3.0 0.13 12.1 3.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region LRR_8 PF13855.6 GBG88696.1 - 0.19 11.5 0.9 80 3.1 0.0 3.8 5 0 0 5 5 5 0 Leucine rich repeat NOA36 PF06524.12 GBG88696.1 - 1.4 8.2 10.7 2.1 7.6 10.7 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 GBG88696.1 - 2 7.7 6.9 2.9 7.2 6.9 1.1 1 0 0 1 1 1 0 SDA1 Radial_spoke PF04712.12 GBG88696.1 - 2.5 7.0 8.3 3.5 6.5 8.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 GBG88696.1 - 5.4 5.0 12.2 7 4.6 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RVT_1 PF00078.27 GBG88697.1 - 5.2e-21 75.2 0.0 8.1e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NlpE_C PF17185.4 GBG88697.1 - 0.029 14.6 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 NlpE C-terminal OB domain TSC22 PF01166.18 GBG88699.1 - 0.0093 16.3 0.1 0.033 14.5 0.1 1.9 2 0 0 2 2 2 1 TSC-22/dip/bun family Prominin PF05478.11 GBG88699.1 - 0.83 7.5 2.5 7.3 4.4 0.0 2.5 3 0 0 3 3 3 0 Prominin FAM76 PF16046.5 GBG88699.1 - 4.5 6.5 9.6 46 3.2 9.6 2.2 1 1 0 1 1 1 0 FAM76 protein F-box PF00646.33 GBG88700.1 - 3e-11 42.9 5.0 5.7e-10 38.8 2.0 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GBG88700.1 - 6.1e-10 38.8 2.3 6.1e-10 38.8 2.3 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GBG88700.1 - 0.00035 20.9 0.1 5.3 7.6 0.0 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG88700.1 - 0.5 10.2 3.6 6 6.7 0.3 3.0 2 1 1 3 3 3 0 Leucine rich repeat F-box-like PF12937.7 GBG88701.1 - 3e-06 27.0 0.1 6.2e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG88701.1 - 0.00019 21.2 0.3 0.00044 20.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 GBG88701.1 - 0.0097 16.3 0.1 0.5 10.9 0.0 3.1 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) TFIIA PF03153.13 GBG88702.1 - 1.2e-06 28.8 21.9 1.6e-06 28.4 21.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Myb_DNA-bind_4 PF13837.6 GBG88702.1 - 2.7e-06 27.7 1.8 2.7e-06 27.7 1.8 2.1 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG88702.1 - 0.0014 18.7 2.2 0.0022 18.0 2.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DNA_pol_phi PF04931.13 GBG88702.1 - 0.0018 16.5 39.3 0.0033 15.6 39.3 1.5 1 0 0 1 1 1 1 DNA polymerase phi Myb_DNA-binding PF00249.31 GBG88702.1 - 1.6 9.0 3.7 1.6 9.0 1.1 2.4 2 1 0 2 2 2 0 Myb-like DNA-binding domain TRAP_alpha PF03896.16 GBG88702.1 - 4.2 6.5 16.6 8.3 5.5 16.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDE_Tnp_4 PF13359.6 GBG88703.1 - 1.1e-26 93.4 0.0 1.7e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88703.1 - 2.5e-17 63.2 0.0 3.5e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88703.1 - 0.0033 17.1 1.3 0.0033 17.1 1.3 2.9 3 1 0 3 3 3 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG88703.1 - 0.0058 17.0 1.8 3.5 8.1 0.0 2.7 3 0 0 3 3 3 2 Transposase DDE domain BatA PF07584.11 GBG88704.1 - 0.036 14.4 2.3 0.074 13.4 2.3 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF5123 PF17161.4 GBG88704.1 - 0.081 14.0 16.2 12 7.0 0.0 5.0 4 1 0 4 4 4 0 Domain of unknown function (DUF5123) Chlam_PMP PF02415.17 GBG88704.1 - 0.16 12.5 66.0 1 10.0 0.3 11.9 11 0 0 11 11 11 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NosD PF05048.13 GBG88704.1 - 0.32 10.2 15.0 2.6 7.3 0.9 3.5 2 2 0 2 2 2 0 Periplasmic copper-binding protein (NosD) NosD PF05048.13 GBG88705.1 - 0.012 14.9 13.6 0.12 11.6 0.4 3.3 2 1 1 3 3 3 0 Periplasmic copper-binding protein (NosD) DUF5123 PF17161.4 GBG88705.1 - 0.019 16.1 14.5 3.2 8.9 0.0 4.8 4 1 1 5 5 5 0 Domain of unknown function (DUF5123) BatA PF07584.11 GBG88705.1 - 0.1 13.0 0.5 0.23 11.9 0.5 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Chlam_PMP PF02415.17 GBG88705.1 - 0.42 11.2 67.6 1 10.0 0.3 11.7 11 0 0 11 11 11 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Cast PF10174.9 GBG88706.1 - 0.067 11.4 14.0 0.088 11.0 14.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF2730 PF10805.8 GBG88706.1 - 0.072 13.2 0.2 0.21 11.7 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) PSY3 PF16836.5 GBG88706.1 - 0.078 12.5 0.6 0.11 12.1 0.6 1.3 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description Spore_coat_CotO PF14153.6 GBG88706.1 - 9.6 6.1 11.1 1.6 8.7 7.5 1.5 2 0 0 2 2 2 0 Spore coat protein CotO MULE PF10551.9 GBG88707.1 - 5.2e-12 46.0 0.3 1.5e-11 44.6 0.0 1.9 2 1 1 3 3 3 1 MULE transposase domain RVT_1 PF00078.27 GBG88708.1 - 6.1e-31 107.7 0.4 1.1e-30 106.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88708.1 - 9.3e-28 96.2 0.0 1.8e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88708.1 - 7.2e-23 80.9 0.0 1.2e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88710.1 - 2.8e-29 102.2 0.1 4.5e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Es2 PF09751.9 GBG88710.1 - 0.12 12.1 15.1 0.19 11.4 15.1 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 DDE_Tnp_4 PF13359.6 GBG88711.1 - 2.4e-30 105.3 0.0 6.2e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 GBG88711.1 - 1.5e-27 96.6 0.2 3.1e-27 95.5 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88711.1 - 9.9e-18 64.4 1.1 2e-17 63.4 1.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Plant_tran PF04827.14 GBG88711.1 - 7.7e-13 48.5 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein rve PF00665.26 GBG88711.1 - 4.6e-12 46.2 0.5 1.3e-11 44.7 0.2 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG88711.1 - 1e-09 38.3 0.1 2.3e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_1 PF01609.21 GBG88711.1 - 0.004 16.8 0.6 0.067 12.8 0.0 2.9 3 0 0 3 3 3 1 Transposase DDE domain DUF1564 PF07600.11 GBG88711.1 - 0.004 16.9 1.1 0.013 15.2 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) V_ATPase_I PF01496.19 GBG88712.1 - 0.11 10.4 5.1 0.14 10.0 5.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med9 PF07544.13 GBG88712.1 - 1 9.5 9.8 6.3 7.0 8.6 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ALMT PF11744.8 GBG88712.1 - 1.3 7.8 4.1 1.9 7.2 4.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA_23 PF13476.6 GBG88712.1 - 1.8 9.0 11.1 3.4 8.1 11.1 1.4 1 0 0 1 1 1 0 AAA domain DUF3498 PF12004.8 GBG88712.1 - 6.7 5.8 18.0 10 5.2 18.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Sigma70_r2 PF04542.14 GBG88713.1 - 0.024 14.4 0.8 0.086 12.6 0.2 2.2 2 0 0 2 2 2 0 Sigma-70 region 2 Peptidase_M19 PF01244.21 GBG88713.1 - 0.045 12.9 0.6 0.097 11.8 0.5 1.6 1 1 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) DDRGK PF09756.9 GBG88713.1 - 0.084 12.5 28.2 0.15 11.7 28.2 1.5 1 0 0 1 1 1 0 DDRGK domain PCB_OB PF17092.5 GBG88713.1 - 0.27 12.0 0.1 0.27 12.0 0.1 2.6 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain DUF659 PF04937.15 GBG88714.1 - 1.7e-23 83.2 0.0 3e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88714.1 - 6.5e-06 25.9 0.4 1.3e-05 24.8 0.4 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SDA1 PF05285.12 GBG88714.1 - 3.4 7.0 8.8 5.3 6.4 8.8 1.2 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG88715.1 - 1.3e-40 139.3 0.0 4e-29 101.7 0.0 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88715.1 - 5.8e-17 61.6 0.0 1.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88715.1 - 2e-13 50.2 0.9 5.3e-13 48.9 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG88715.1 - 1.4e-10 41.4 0.0 3.7e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG88715.1 - 1.2e-09 38.4 0.0 5.3e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG88715.1 - 1.1e-07 32.2 0.0 2e-06 28.3 0.0 2.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG88715.1 - 4.9e-07 29.9 0.5 0.057 13.7 0.1 3.1 2 0 0 2 2 2 2 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG88715.1 - 5.4e-05 23.7 0.0 0.00073 20.1 0.0 2.8 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG88715.1 - 5.6e-05 22.9 0.5 0.0015 18.3 0.7 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG88715.1 - 0.0077 16.5 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 GBG88715.1 - 0.027 14.2 0.3 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG88716.1 - 3.6e-12 46.2 0.0 9.3e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88716.1 - 1.4e-05 25.2 0.0 2.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain His_Phos_2 PF00328.22 GBG88716.1 - 0.052 12.9 0.2 0.071 12.4 0.2 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) RVT_1 PF00078.27 GBG88717.1 - 1.6e-30 106.3 0.0 2.7e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG88717.1 - 3.4e-16 59.5 0.0 8.5e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG88718.1 - 0.016 15.5 0.1 0.065 13.5 0.1 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein rve PF00665.26 GBG88719.1 - 3.7e-17 62.6 0.0 6.2e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG88719.1 - 6.1e-14 51.9 0.4 1.8e-13 50.3 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 GBG88719.1 - 0.011 15.4 0.0 0.035 13.9 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 GBG88719.1 - 0.083 13.1 0.2 0.2 11.9 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG88721.1 - 9.1e-06 26.2 0.0 1.7e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88721.1 - 5.5e-05 23.7 0.0 0.0001 22.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG88721.1 - 0.0002 21.6 0.0 0.00039 20.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88721.1 - 0.0046 16.8 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG88722.1 - 0.042 14.1 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG88722.1 - 0.076 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88722.1 - 0.08 13.5 0.1 0.18 12.4 0.1 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG88722.1 - 0.17 11.9 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88723.1 - 8.7e-30 103.9 0.1 1.3e-29 103.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88723.1 - 7.6e-22 77.2 0.0 1.6e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88723.1 - 4.4e-18 65.5 0.0 8.8e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG88723.1 - 2.9e-07 30.3 0.0 4.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG88723.1 - 2.2e-06 28.2 0.0 4.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88723.1 - 3.3e-06 27.6 0.0 6.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88723.1 - 1.1e-05 25.2 0.0 2.9e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG88724.1 - 2.6e-34 117.2 0.1 6e-34 116.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88724.1 - 5.2e-31 107.0 0.2 1.7e-30 105.4 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88724.1 - 2.4e-10 40.3 0.0 4.5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88724.1 - 9.5e-08 32.0 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Apc13p PF05839.11 GBG88724.1 - 0.63 10.3 2.9 0.85 9.8 1.3 2.0 2 0 0 2 2 2 0 Apc13p protein RT_RNaseH_2 PF17919.1 GBG88725.1 - 2.8e-20 72.2 0.0 2.7e-19 69.1 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88725.1 - 1.7e-15 57.3 0.0 7e-15 55.3 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG88725.1 - 2.3e-14 53.2 0.1 4.5e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG88725.1 - 7e-13 48.8 0.1 1.6e-08 34.8 0.0 2.9 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG88725.1 - 0.16 11.6 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RVT_1 PF00078.27 GBG88726.1 - 2e-27 96.2 0.0 4.3e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG88726.1 - 0.035 14.4 0.1 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG88727.1 - 1.6e-32 112.9 0.0 2.8e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88727.1 - 4.3e-29 100.5 0.0 9.3e-29 99.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88727.1 - 2.8e-25 88.6 0.0 5.8e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88727.1 - 3.2e-16 59.6 0.0 6.6e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG88727.1 - 6.7e-13 48.5 0.1 5.1e-12 45.7 0.0 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 GBG88727.1 - 0.047 13.5 0.0 0.19 11.5 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain FlaC_arch PF05377.11 GBG88727.1 - 0.21 12.0 3.4 0.84 10.1 1.6 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) YscO PF07321.12 GBG88727.1 - 1.5 8.8 11.6 0.11 12.5 4.6 2.4 2 0 0 2 2 2 0 Type III secretion protein YscO DsrH PF04077.12 GBG88728.1 - 0.019 15.1 0.0 26 5.0 0.0 4.0 1 1 4 5 5 5 0 DsrH like protein SeleniumBinding PF11524.8 GBG88728.1 - 0.24 11.8 10.5 92 3.6 0.1 5.0 1 1 4 5 5 5 0 Selenium binding protein PBSX_XtrA PF17356.2 GBG88728.1 - 1.8 8.5 7.4 19 5.3 0.2 3.7 4 0 0 4 4 4 0 Phage-like element PBSX protein XtrA ICL PF00463.21 GBG88728.1 - 5.3 5.4 6.4 14 4.0 1.5 2.2 1 1 1 2 2 2 0 Isocitrate lyase family Elong-fact-P_C PF09285.11 GBG88728.1 - 6.5 6.6 8.1 24 4.8 0.2 3.9 2 2 3 5 5 5 0 Elongation factor P, C-terminal DsrH PF04077.12 GBG88729.1 - 1.5e-05 25.0 4.2 66 3.7 0.0 8.9 2 2 10 13 13 13 1 DsrH like protein DDE_Tnp_4 PF13359.6 GBG88730.1 - 2.1e-33 115.2 0.0 1.1e-32 112.8 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88730.1 - 6.2e-16 58.6 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88730.1 - 1.9e-05 24.4 0.3 0.011 15.4 0.0 2.7 3 0 0 3 3 3 2 Transposase DDE domain Integrase_H2C2 PF17921.1 GBG88731.1 - 3.6e-13 49.4 0.9 8.9e-13 48.1 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG88731.1 - 2.9e-05 23.7 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88731.1 - 0.00016 21.6 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88731.1 - 0.00095 19.4 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG88731.1 - 0.01 16.1 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG88731.1 - 0.063 13.5 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Met_10 PF02475.16 GBG88733.1 - 1.8e-30 106.2 0.0 3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Kelch_4 PF13418.6 GBG88733.1 - 8.6e-24 83.3 1.6 3.7e-06 26.8 0.0 6.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG88733.1 - 5.4e-22 77.3 0.3 9.8e-05 22.3 0.1 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 GBG88733.1 - 2.4e-21 75.5 5.7 8.1e-09 35.6 0.0 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GBG88733.1 - 2.2e-20 72.2 1.5 1.1e-06 28.7 0.0 6.6 7 1 0 7 7 7 3 Kelch motif Kelch_1 PF01344.25 GBG88733.1 - 1e-13 50.6 1.1 0.015 14.8 0.0 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GBG88733.1 - 4.2e-10 39.2 2.4 0.00014 21.6 0.1 6.2 6 0 0 6 6 6 2 Kelch motif MTS PF05175.14 GBG88733.1 - 0.005 16.4 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GBG88733.1 - 0.099 13.4 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Zip PF02535.22 GBG88733.1 - 9.8 5.3 10.9 2.6 7.2 2.9 2.6 3 0 0 3 3 3 0 ZIP Zinc transporter Dimer_Tnp_hAT PF05699.14 GBG88735.1 - 0.0064 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Astro_capsid_p PF12226.8 GBG88736.1 - 2.6 7.1 7.1 3.2 6.8 7.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 GBG88736.1 - 3.9 5.5 10.4 4.6 5.2 10.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF563 PF04577.14 GBG88737.1 - 6.7e-16 59.1 0.0 5.6e-12 46.2 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF563) DUF1676 PF07898.13 GBG88738.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Ldh_1_C PF02866.18 GBG88739.1 - 8.2e-23 81.1 0.0 1.1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GBG88739.1 - 5.8e-22 78.3 0.4 9.5e-22 77.6 0.2 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain RalF_SCD PF18248.1 GBG88741.1 - 0.06 13.3 0.0 15 5.5 0.0 2.3 2 0 0 2 2 2 0 RalF C-terminal Sec-7 capping domain Nop14 PF04147.12 GBG88742.1 - 0.013 13.8 18.1 0.014 13.7 18.1 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 GBG88742.1 - 0.013 15.7 21.1 0.017 15.4 21.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 GBG88742.1 - 0.037 12.3 11.6 0.034 12.4 11.6 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 GBG88742.1 - 0.29 10.7 22.7 0.39 10.3 22.7 1.1 1 0 0 1 1 1 0 PPP4R2 VIR_N PF15912.5 GBG88742.1 - 1.2 8.7 22.5 1.7 8.2 22.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal NOA36 PF06524.12 GBG88742.1 - 1.5 8.1 18.8 2.4 7.4 18.8 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4820 PF16091.5 GBG88742.1 - 1.5 8.1 7.4 2.2 7.6 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PA26 PF04636.13 GBG88742.1 - 2.1 7.1 3.4 2.2 7.1 3.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Merozoite_SPAM PF07133.11 GBG88742.1 - 2.4 8.1 33.1 3.9 7.4 33.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.15 GBG88742.1 - 3.2 6.4 8.4 3.2 6.4 8.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PSK PF06404.12 GBG88742.1 - 4.1 8.5 9.1 9.5 7.3 9.1 1.6 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) TRAP_alpha PF03896.16 GBG88742.1 - 4.7 6.3 14.0 6.7 5.8 14.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit V_ATPase_I PF01496.19 GBG88742.1 - 6.1 4.6 7.0 6.9 4.5 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COPI_C PF06957.11 GBG88742.1 - 6.2 5.5 8.6 8.7 5.0 8.6 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Connexin PF00029.19 GBG88742.1 - 6.7 6.4 5.2 11 5.7 5.2 1.3 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 GBG88742.1 - 8.2 5.1 11.7 10 4.8 11.7 1.2 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG88743.1 - 3e-33 113.8 0.0 5.6e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88743.1 - 3.4e-21 75.5 0.0 7e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAD_binding_4 PF01565.23 GBG88745.1 - 9.3e-35 119.4 0.0 2.4e-34 118.1 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 GBG88745.1 - 5.4e-19 68.8 0.6 4.3e-16 59.3 0.0 2.3 1 1 1 2 2 2 2 FAD linked oxidases, C-terminal domain Ribosomal_L13 PF00572.18 GBG88745.1 - 2.1e-08 34.4 0.0 1.1e-07 32.2 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L13 FAD_binding_4 PF01565.23 GBG88746.1 - 9.1e-35 119.4 0.0 2.3e-34 118.1 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 GBG88746.1 - 1.3e-17 64.3 0.0 2.2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Ribosomal_L13 PF00572.18 GBG88746.1 - 2e-08 34.5 0.0 1e-07 32.2 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L13 FAD_binding_4 PF01565.23 GBG88747.1 - 2.4e-38 131.0 0.0 5.2e-38 129.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 GBG88747.1 - 6.3e-18 65.3 0.0 1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Presenilin PF01080.17 GBG88748.1 - 0.48 9.1 1.8 0.76 8.5 1.8 1.3 1 0 0 1 1 1 0 Presenilin Presenilin PF01080.17 GBG88749.1 - 0.38 9.5 2.2 0.35 9.6 2.2 1.0 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 GBG88749.1 - 0.45 10.3 10.8 0.57 10.0 10.8 1.1 1 0 0 1 1 1 0 Coilin N-terminus Gram_pos_anchor PF00746.21 GBG88749.1 - 0.9 9.5 4.1 5.3 7.1 0.5 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DTHCT PF08070.11 GBG88749.1 - 2.6 8.8 10.8 3.3 8.5 10.8 1.1 1 0 0 1 1 1 0 DTHCT (NUC029) region DUF2967 PF11179.8 GBG88749.1 - 2.8 5.9 5.6 2.7 6.0 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Protocadherin PF08374.11 GBG88749.1 - 3.5 7.5 5.9 4.4 7.2 5.9 1.1 1 0 0 1 1 1 0 Protocadherin PGA2 PF07543.12 GBG88749.1 - 3.7 7.5 14.9 5 7.1 14.9 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 RNA_polI_A34 PF08208.11 GBG88749.1 - 7.3 6.6 20.3 9.8 6.2 20.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ATP-synt_E PF05680.12 GBG88749.1 - 8.1 6.9 10.7 12 6.4 10.7 1.2 1 0 0 1 1 1 0 ATP synthase E chain YqfQ PF14181.6 GBG88750.1 - 0.051 13.8 0.9 0.075 13.2 0.9 1.4 1 1 0 1 1 1 0 YqfQ-like protein CobT PF06213.12 GBG88750.1 - 0.062 12.7 16.8 0.072 12.5 16.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT V_ATPase_I PF01496.19 GBG88750.1 - 0.099 10.5 0.0 0.11 10.4 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SpoIIIAH PF12685.7 GBG88750.1 - 0.17 11.7 7.7 0.2 11.5 7.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein TRAP_alpha PF03896.16 GBG88750.1 - 0.6 9.3 12.0 0.84 8.8 12.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.11 GBG88750.1 - 2.8 7.5 18.0 3.7 7.1 18.0 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GBG88750.1 - 7.7 4.6 24.3 8.3 4.5 24.3 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 GBG88750.1 - 9.3 4.7 20.8 11 4.5 20.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 GBG88750.1 - 10 4.8 8.8 9.6 4.9 8.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sucrose_synth PF00862.19 GBG88751.1 - 1.3e-12 46.8 0.0 3.2e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG88751.1 - 2.2e-12 46.9 0.0 3.8e-10 39.6 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 RVT_1 PF00078.27 GBG88751.1 - 1.2e-09 38.1 0.1 1.9e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG88751.1 - 6.9e-09 35.6 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Glyco_trans_4_4 PF13579.6 GBG88751.1 - 6.3e-07 30.0 0.2 2.1e-06 28.3 0.2 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Asp_protease_2 PF13650.6 GBG88751.1 - 1e-06 29.3 0.0 2.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Glyco_trans_1_4 PF13692.6 GBG88751.1 - 2.2e-06 28.1 0.0 9.8e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 gag-asp_proteas PF13975.6 GBG88751.1 - 2.1e-05 25.0 0.0 4.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Glyco_transf_4 PF13439.6 GBG88751.1 - 0.00011 22.3 0.1 0.00076 19.5 0.1 2.4 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DUF1752 PF08550.10 GBG88751.1 - 0.0035 17.1 0.8 0.012 15.4 0.4 2.1 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1752) Asp_protease PF09668.10 GBG88751.1 - 0.08 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Arg_decarb_HB PF17810.1 GBG88752.1 - 5.5e-20 71.4 0.0 3.9e-19 68.7 0.0 2.2 2 0 0 2 2 2 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 GBG88752.1 - 1.4e-12 47.9 0.7 3.6e-12 46.6 0.7 1.7 1 0 0 1 1 1 1 Arginine decarboxylase C-terminal helical extension Orn_Arg_deC_N PF02784.16 GBG88752.1 - 6.8e-12 45.3 0.0 1.9e-10 40.5 0.0 2.2 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain CDC37_N PF03234.14 GBG88753.1 - 0.25 12.3 9.0 0.3 12.0 9.0 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding RPN2_C PF18004.1 GBG88753.1 - 0.69 9.8 15.1 0.91 9.4 15.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC27 PF09507.10 GBG88753.1 - 0.74 9.1 17.3 0.88 8.9 17.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PA26 PF04636.13 GBG88753.1 - 0.76 8.6 8.0 0.79 8.6 8.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF763 PF05559.11 GBG88753.1 - 0.84 8.8 3.4 1.1 8.4 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) zf-CCHC PF00098.23 GBG88755.1 - 3.1e-07 30.1 2.4 8.1e-07 28.8 2.4 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG88755.1 - 0.00083 19.1 2.5 0.0016 18.3 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Patched PF02460.18 GBG88756.1 - 0.0048 15.0 1.4 0.0072 14.5 1.4 1.2 1 0 0 1 1 1 1 Patched family BUD22 PF09073.10 GBG88756.1 - 0.0064 15.9 35.4 0.0099 15.3 35.4 1.2 1 0 0 1 1 1 1 BUD22 LAP1C PF05609.12 GBG88756.1 - 0.2 10.7 19.2 0.33 10.0 19.2 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4746 PF15928.5 GBG88756.1 - 3.7 6.9 23.8 0.15 11.5 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF4551 PF15087.6 GBG88756.1 - 4.8 5.9 20.1 5.7 5.6 20.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RT_RNaseH_2 PF17919.1 GBG88757.1 - 8.2e-24 83.5 0.0 1.8e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88757.1 - 3.4e-20 72.3 0.0 7.3e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88757.1 - 9.4e-16 57.7 0.0 3.2e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88757.1 - 4.8e-13 49.3 0.0 2.1e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG88757.1 - 0.002 18.3 0.0 0.0052 17.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG88757.1 - 0.14 11.9 0.0 0.52 10.1 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain RdDM_RDM1 PF09187.10 GBG88758.1 - 0.035 14.2 0.4 0.043 13.9 0.4 1.1 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 Cas_Csm6 PF09659.10 GBG88758.1 - 0.12 11.2 4.5 0.15 10.8 4.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) CSN5_C PF18323.1 GBG88758.1 - 0.39 11.7 4.6 0.63 11.0 4.6 1.3 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF763 PF05559.11 GBG88758.1 - 0.45 9.7 7.1 0.51 9.5 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) YtxH PF12732.7 GBG88758.1 - 0.54 10.8 6.9 1.1 9.8 6.9 1.6 1 1 0 1 1 1 0 YtxH-like protein MRPL52 PF18699.1 GBG88758.1 - 0.82 9.9 0.0 0.82 9.9 0.0 2.9 1 1 1 2 2 2 0 Mitoribosomal protein mL52 DUF2499 PF10693.9 GBG88758.1 - 1.1 9.6 7.3 5.5 7.3 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2499) RRM_1 PF00076.22 GBG88761.1 - 1.8e-44 149.4 0.0 3.9e-24 84.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 GBG88761.1 - 1e-17 65.0 0.0 4.3e-17 63.0 0.0 2.2 2 1 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_7 PF16367.5 GBG88761.1 - 0.051 13.7 0.0 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif gag-asp_proteas PF13975.6 GBG88762.1 - 1.4e-05 25.6 0.0 4.4e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88762.1 - 0.0016 19.1 0.0 0.0042 17.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88762.1 - 0.046 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG88762.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG88762.1 - 0.094 13.0 0.1 0.35 11.2 0.1 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein GRP PF07172.11 GBG88762.1 - 1 10.1 8.1 2.7 8.8 8.1 1.7 1 0 0 1 1 1 0 Glycine rich protein family SRP-alpha_N PF04086.13 GBG88762.1 - 5.7 6.8 19.7 0.019 14.9 8.9 2.2 3 0 0 3 3 3 0 Signal recognition particle, alpha subunit, N-terminal Exo_endo_phos PF03372.23 GBG88763.1 - 1.8e-24 86.6 0.0 3.2e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 GBG88763.1 - 7.2e-09 35.8 4.7 1.4e-08 34.9 4.7 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 GBG88763.1 - 0.026 14.6 5.7 0.052 13.6 5.7 1.5 1 0 0 1 1 1 0 MYND finger ACC_epsilon PF13822.6 GBG88764.1 - 0.24 12.1 0.3 0.24 12.1 0.3 2.7 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit REV PF00424.18 GBG88764.1 - 0.27 11.3 5.4 0.31 11.1 0.4 2.9 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) DUF3138 PF11336.8 GBG88764.1 - 3.9 6.0 5.0 6.5 5.2 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Rotamase_2 PF13145.6 GBG88765.1 - 0.052 14.4 2.7 0.052 14.4 2.7 2.7 1 1 1 2 2 2 0 PPIC-type PPIASE domain REV PF00424.18 GBG88765.1 - 0.083 12.9 4.8 0.14 12.2 0.7 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF2950 PF11453.8 GBG88765.1 - 0.12 11.6 8.6 0.16 11.1 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) DUF3138 PF11336.8 GBG88765.1 - 0.62 8.6 3.1 1.1 7.8 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Aldedh PF00171.22 GBG88766.1 - 3.5e-125 418.1 0.0 5.1e-125 417.6 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GBG88766.1 - 0.0079 15.3 0.0 0.64 9.0 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) DUF218 PF02698.17 GBG88766.1 - 0.032 14.3 0.1 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 DUF218 domain Morc6_S5 PF17942.1 GBG88767.1 - 1.5e-47 161.2 5.4 4.5e-39 133.7 0.1 3.4 3 0 0 3 3 3 2 Morc6 ribosomal protein S5 domain 2-like RT_RNaseH_2 PF17919.1 GBG88767.1 - 1.4e-23 82.8 0.0 6.8e-23 80.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88767.1 - 4.8e-22 78.2 0.0 1.8e-21 76.4 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88767.1 - 7.6e-21 74.7 0.3 7e-20 71.5 0.3 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HATPase_c_3 PF13589.6 GBG88767.1 - 3.5e-14 52.8 2.1 7.2e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RVP_2 PF08284.11 GBG88767.1 - 9.9e-08 31.8 0.0 2.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88767.1 - 1.6e-07 31.9 0.2 2.3e-06 28.1 0.0 2.8 2 1 1 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88767.1 - 1.1e-05 26.0 0.1 4.1e-05 24.0 0.0 2.2 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease HATPase_c PF02518.26 GBG88767.1 - 0.00013 22.5 0.2 0.00039 20.9 0.0 1.8 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Retrotrans_gag PF03732.17 GBG88767.1 - 0.00092 19.4 0.3 0.025 14.9 0.1 5.0 6 0 0 6 6 4 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG88767.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 GBG88767.1 - 0.024 14.8 0.1 0.093 12.9 0.1 2.0 1 0 0 1 1 1 0 Integrase core domain SICA_beta PF12878.7 GBG88767.1 - 0.041 14.0 0.1 0.041 14.0 0.1 2.5 2 0 0 2 2 2 0 SICA extracellular beta domain DUF4187 PF13821.6 GBG88767.1 - 0.088 12.6 2.6 0.41 10.5 2.6 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) SMBP PF16785.5 GBG88767.1 - 0.17 12.1 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 1 0 Small metal-binding protein MPS2 PF17060.5 GBG88767.1 - 2 7.6 13.1 5.7 6.1 13.1 1.7 1 0 0 1 1 1 0 Monopolar spindle protein 2 Pec_lyase_C PF00544.19 GBG88768.1 - 1.4e-15 57.5 2.1 8.7e-15 54.9 2.1 1.9 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG88768.1 - 1.1e-09 38.4 0.6 3.5e-09 36.7 0.6 1.8 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG88768.1 - 0.00012 21.5 0.1 0.00037 19.8 0.1 1.6 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) TIG PF01833.24 GBG88770.1 - 1.2e-27 95.7 7.2 9.9e-13 48.0 0.6 3.4 3 0 0 3 3 3 2 IPT/TIG domain RVT_1 PF00078.27 GBG88770.1 - 3.5e-25 88.8 0.0 5.9e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88770.1 - 1.5e-17 63.5 0.8 3.5e-17 62.3 0.8 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG88770.1 - 3.3e-13 49.5 0.0 9.7e-09 35.2 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88770.1 - 7.9e-12 45.4 0.2 1.8e-08 34.6 0.2 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG88770.1 - 2.8e-06 27.9 0.0 6.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88770.1 - 9.9e-06 26.0 0.0 2.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88770.1 - 0.0004 20.1 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88770.1 - 0.0038 17.0 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG88770.1 - 0.0083 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG88770.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Formyl_trans_N PF00551.19 GBG88771.1 - 2.7e-34 118.5 0.0 9.3e-34 116.7 0.0 1.9 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 GBG88771.1 - 2.3e-17 63.1 0.0 5e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Myosin_head PF00063.21 GBG88772.1 - 1.9e-250 832.7 0.1 3e-250 832.1 0.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 GBG88772.1 - 2.9e-19 69.3 2.7 4.2e-19 68.7 0.2 2.7 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 GBG88772.1 - 3e-05 23.4 22.7 0.9 9.5 0.9 6.5 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.19 GBG88772.1 - 0.0047 16.7 0.9 0.011 15.6 0.9 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Hpr_kinase_C PF07475.12 GBG88772.1 - 0.059 12.9 0.6 2.7 7.5 0.1 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 GBG88772.1 - 0.12 12.7 0.1 0.12 12.7 0.1 4.1 2 1 0 2 2 2 0 AAA ATPase domain DUF659 PF04937.15 GBG88773.1 - 3.6e-14 52.9 0.0 5.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG88774.1 - 3.4e-14 53.0 0.0 5.5e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG88775.1 - 1.2e-17 64.0 0.0 2.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88775.1 - 5.4e-15 55.3 0.0 1.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG88775.1 - 1.7e-10 41.3 0.0 4.2e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88775.1 - 1.6e-08 35.1 0.0 3.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG88775.1 - 4e-08 33.1 0.0 7.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG88775.1 - 0.00097 18.9 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG88775.1 - 0.0044 17.3 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease MDH PF02315.16 GBG88775.1 - 0.1 12.6 0.2 0.77 9.9 0.4 2.4 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit LSM PF01423.22 GBG88776.1 - 8.5e-18 63.8 0.1 1.1e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain Myb_DNA-bind_4 PF13837.6 GBG88777.1 - 3.1e-07 30.7 1.9 5.7e-07 29.8 1.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG88777.1 - 0.0029 17.9 1.9 0.0079 16.5 0.7 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG88777.1 - 0.069 13.2 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF647 PF04884.14 GBG88778.1 - 5.8e-61 206.2 0.1 8.3e-61 205.7 0.1 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF4006 PF13179.6 GBG88779.1 - 0.0019 18.1 0.3 0.42 10.6 0.0 3.3 2 1 1 3 3 3 1 Family of unknown function (DUF4006) ACT PF01842.25 GBG88779.1 - 0.0086 15.8 0.1 0.027 14.2 0.1 1.9 1 0 0 1 1 1 1 ACT domain FAM176 PF14851.6 GBG88779.1 - 0.023 14.3 0.9 0.023 14.3 0.9 3.2 2 1 1 3 3 3 0 FAM176 family ACT_4 PF13291.6 GBG88779.1 - 0.11 13.0 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 ACT domain PAP1 PF08601.10 GBG88779.1 - 3.6 7.2 9.3 0.3 10.8 3.9 1.7 1 1 1 2 2 2 0 Transcription factor PAP1 Asp-B-Hydro_N PF05279.11 GBG88779.1 - 7.3 6.6 35.3 0.18 11.8 10.2 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region RsfS PF02410.15 GBG88780.1 - 0.00026 21.3 0.0 0.00066 20.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation UPF0086 PF01868.16 GBG88781.1 - 1.8e-19 69.4 0.0 3.6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Borrelia_rep PF03183.13 GBG88781.1 - 0.11 12.5 0.6 0.25 11.4 0.6 1.6 1 0 0 1 1 1 0 Borrelia repeat protein GMP_synt_C PF00958.22 GBG88782.1 - 3.2e-41 139.3 0.0 6.4e-41 138.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 GBG88782.1 - 2.7e-35 121.9 0.0 3.8e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GBG88782.1 - 2.8e-10 40.3 0.1 1.2e-09 38.3 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 GBG88782.1 - 1.2e-07 31.1 0.0 0.00074 18.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 GBG88782.1 - 0.00064 18.6 0.0 0.00098 18.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 GBG88782.1 - 0.0011 18.5 0.0 0.11 12.0 0.0 2.6 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 GBG88782.1 - 0.0033 17.0 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 GBG88782.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2917 PF11142.8 GBG88783.1 - 0.06 12.7 0.0 0.2 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Miga PF10265.9 GBG88783.1 - 0.31 10.0 5.3 0.5 9.3 5.3 1.2 1 0 0 1 1 1 0 Mitoguardin RT_RNaseH_2 PF17919.1 GBG88786.1 - 5e-28 97.1 0.0 2.7e-27 94.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88786.1 - 6.2e-23 81.1 0.0 2.8e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88786.1 - 6.9e-08 32.3 0.2 1.3e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG88786.1 - 6e-06 26.1 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88786.1 - 2.6e-05 24.8 0.0 6.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88786.1 - 0.0056 17.2 0.1 0.043 14.4 0.1 2.5 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG88786.1 - 0.007 16.2 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG88786.1 - 0.026 14.3 0.0 0.35 10.7 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG88788.1 - 6.8e-25 87.0 0.0 1.1e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88788.1 - 1.9e-22 79.5 0.0 3.1e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ABC_membrane_2 PF06472.15 GBG88789.1 - 7.1e-25 87.9 0.2 4.6e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 2-Hacid_dh_C PF02826.19 GBG88790.1 - 3e-32 111.4 0.0 5.2e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RVT_1 PF00078.27 GBG88790.1 - 1.8e-14 53.8 0.0 3.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG88790.1 - 1.2e-07 32.2 0.0 3.8e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88790.1 - 2.4e-07 30.6 0.0 4.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88790.1 - 7.1e-07 29.8 0.0 2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88790.1 - 0.00024 20.9 0.0 0.0007 19.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG88790.1 - 0.0096 16.2 0.3 0.029 14.7 0.3 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein 2-Hacid_dh PF00389.30 GBG88790.1 - 0.035 13.8 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PSD4 PF07631.11 GBG88790.1 - 0.089 13.3 0.2 0.2 12.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Integrase_H2C2 PF17921.1 GBG88791.1 - 8.8e-19 67.4 0.2 1.8e-18 66.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88791.1 - 2.1e-15 57.0 0.3 6.3e-15 55.4 0.2 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG88791.1 - 2.3e-05 24.5 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF2862 PF11061.8 GBG88791.1 - 0.095 12.5 0.1 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) Integrase_H2C2 PF17921.1 GBG88792.1 - 6.6e-19 67.8 0.2 1.4e-18 66.8 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88792.1 - 2.2e-15 56.9 0.2 4.3e-15 55.9 0.2 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG88792.1 - 1.7e-05 24.9 0.0 3.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF2862 PF11061.8 GBG88792.1 - 0.092 12.6 0.4 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) Retrotrans_gag PF03732.17 GBG88794.1 - 6.1e-07 29.6 5.2 0.0096 16.2 0.2 4.3 3 1 1 4 4 4 2 Retrotransposon gag protein DUF4187 PF13821.6 GBG88794.1 - 0.0047 16.7 1.2 0.014 15.2 1.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3499 PF12005.8 GBG88794.1 - 7.9 7.1 10.0 6.5 7.4 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Pkinase PF00069.25 GBG88795.1 - 2.9e-48 164.5 0.0 4.7e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG88795.1 - 2.1e-38 132.1 0.0 3.4e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DDE_Tnp_4 PF13359.6 GBG88795.1 - 5.1e-27 94.5 0.0 1.4e-26 93.0 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88795.1 - 1.4e-14 54.2 0.0 2.8e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein APH PF01636.23 GBG88795.1 - 0.0085 16.0 1.1 0.021 14.8 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family DDE_Tnp_1 PF01609.21 GBG88795.1 - 0.036 13.7 1.1 0.21 11.2 0.0 2.5 3 0 0 3 3 3 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG88796.1 - 1.3e-09 38.3 3.8 1.9e-09 37.8 1.6 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG88796.1 - 0.0001 22.6 2.3 0.0011 19.3 0.5 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG88796.1 - 0.00012 22.2 0.1 0.00033 20.8 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG88796.1 - 0.00028 21.1 0.6 0.0006 20.0 0.6 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG88796.1 - 0.0074 16.3 0.9 0.015 15.4 0.3 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 GBG88796.1 - 0.079 14.0 0.4 0.17 12.9 0.4 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG88798.1 - 5.3e-42 141.9 0.0 1.3e-19 70.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88798.1 - 1.1e-38 131.7 0.0 4.6e-18 65.4 0.0 3.2 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88798.1 - 3.2e-19 69.3 0.0 3.3e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MIB_HERC2 PF06701.13 GBG88798.1 - 0.00015 21.9 0.2 1.4 9.2 0.0 3.1 2 0 0 2 2 2 2 Mib_herc2 Cbl_N PF02262.16 GBG88798.1 - 0.018 15.0 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Complex1_LYR PF05347.15 GBG88798.1 - 0.1 12.7 0.0 32 4.7 0.0 2.9 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Drf_GBD PF06371.13 GBG88798.1 - 0.19 11.3 0.0 17 4.9 0.0 2.6 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain CcdA PF07362.12 GBG88798.1 - 0.71 10.3 3.4 37 4.8 0.3 2.9 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA zf-CCHC_5 PF14787.6 GBG88798.1 - 0.96 9.2 3.4 2.6 7.8 3.4 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SDA1 PF05285.12 GBG88800.1 - 1.9 7.8 15.9 2.5 7.4 15.9 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 GBG88800.1 - 5.5 6.3 18.7 8 5.8 18.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 GBG88800.1 - 7.4 4.6 16.6 9.5 4.3 16.6 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 GBG88800.1 - 8.5 5.5 7.4 49 3.0 8.4 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit RVT_1 PF00078.27 GBG88801.1 - 1.1e-28 100.2 0.1 1.7e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88801.1 - 1.2e-19 70.2 0.0 3.1e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88801.1 - 2.2e-19 69.3 0.4 6.3e-19 67.8 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG88801.1 - 9.4e-10 38.7 0.0 2.5e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88801.1 - 1.3e-07 31.8 0.0 3.9e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG88801.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG88801.1 - 0.089 13.0 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Pkinase PF00069.25 GBG88802.1 - 7.7e-50 169.7 0.0 1.4e-49 168.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG88802.1 - 3.1e-44 151.2 0.0 5.8e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG88802.1 - 0.064 13.2 0.7 0.17 11.8 0.5 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG88802.1 - 0.081 11.7 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Esterase PF00756.20 GBG88803.1 - 9.6e-14 51.6 0.0 1.9e-10 40.8 0.0 2.9 2 0 0 2 2 2 2 Putative esterase Hydrolase_4 PF12146.8 GBG88803.1 - 0.00023 20.5 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SR-25 PF10500.9 GBG88803.1 - 0.00042 20.0 10.6 0.00042 20.0 10.6 3.0 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein RNase_H2_suC PF08615.11 GBG88803.1 - 0.0023 18.1 5.9 0.42 10.8 0.3 3.4 3 0 0 3 3 3 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Tannase PF07519.11 GBG88803.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 GBG88803.1 - 0.019 14.5 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GBG88803.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MPP6 PF10175.9 GBG88803.1 - 1.7 9.1 23.5 0.6 10.6 4.1 3.4 3 0 0 3 3 3 0 M-phase phosphoprotein 6 DDHD PF02862.17 GBG88803.1 - 4.8 7.3 6.2 3.1 7.9 0.0 2.7 2 1 0 2 2 2 0 DDHD domain SpoIIP PF07454.11 GBG88803.1 - 5.1 6.5 8.4 2.9 7.3 1.9 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RT_RNaseH_2 PF17919.1 GBG88804.1 - 9.5e-35 118.6 0.1 1.7e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88804.1 - 3.8e-30 104.3 0.1 7.6e-30 103.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88804.1 - 6.3e-25 88.0 0.0 1.2e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88805.1 - 2e-16 59.8 0.4 5.8e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG88805.1 - 1.6e-10 41.2 0.0 2.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG88805.1 - 1.5e-05 25.1 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger FAD_binding_4 PF01565.23 GBG88807.1 - 8.9e-26 90.3 0.2 8.9e-26 90.3 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain ALO PF04030.14 GBG88807.1 - 1.1e-18 68.0 4.4 3.7e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase DUF737 PF05300.11 GBG88807.1 - 7.9 6.8 6.1 4.9 7.5 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF737) PH PF00169.29 GBG88808.1 - 3.4e-07 30.7 0.0 6.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 PH domain FAM76 PF16046.5 GBG88808.1 - 0.7 9.2 2.8 0.61 9.4 1.6 1.4 1 1 0 1 1 1 0 FAM76 protein AAA_13 PF13166.6 GBG88808.1 - 3.8 6.0 8.5 6 5.4 8.5 1.2 1 0 0 1 1 1 0 AAA domain Ribosomal_60s PF00428.19 GBG88808.1 - 5.6 7.6 21.7 3.3 8.4 5.2 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Porphobil_deam PF01379.20 GBG88810.1 - 3.5e-74 248.7 0.0 4.6e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 GBG88810.1 - 1.9e-12 47.3 0.1 3.8e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Na_H_Exchanger PF00999.21 GBG88811.1 - 5e-62 209.9 48.9 3.3e-32 111.7 18.9 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family DER1 PF04511.15 GBG88812.1 - 2.4e-59 200.5 10.1 2.7e-59 200.3 10.1 1.0 1 0 0 1 1 1 1 Der1-like family DUF1331 PF07048.11 GBG88812.1 - 0.021 14.5 0.2 0.075 12.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Oleosin PF01277.17 GBG88812.1 - 0.041 13.6 1.0 0.11 12.3 0.2 1.9 1 1 0 2 2 2 0 Oleosin DUF212 PF02681.14 GBG88813.1 - 7.5e-37 126.3 1.4 3.7e-34 117.6 0.0 2.6 2 0 0 2 2 2 2 Divergent PAP2 family LapA_dom PF06305.11 GBG88814.1 - 0.039 13.8 0.1 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain T2SSM PF04612.12 GBG88814.1 - 0.053 13.6 6.2 0.98 9.5 0.1 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DDE_Tnp_4 PF13359.6 GBG88815.1 - 9.2e-27 93.6 0.0 2e-26 92.5 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88815.1 - 2.3e-12 46.9 0.0 3.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88815.1 - 6.9e-06 25.9 0.2 4e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain Sugar_tr PF00083.24 GBG88816.1 - 6.6e-26 91.2 23.8 3.7e-22 78.8 9.9 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GBG88816.1 - 1.5e-25 89.9 52.8 1.5e-20 73.5 27.5 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.13 GBG88816.1 - 0.0039 15.6 5.2 0.0039 15.6 5.2 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector Isochorismatase PF00857.20 GBG88817.1 - 9.1e-39 133.4 0.1 1.1e-38 133.1 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF1990 PF09348.10 GBG88818.1 - 1.5e-34 119.3 3.0 5.1e-15 55.8 0.1 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF1990) Ribosomal_L34e PF01199.18 GBG88818.1 - 2.7e-27 94.9 2.5 2.7e-27 94.9 2.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L34e CENP-B_dimeris PF09026.10 GBG88818.1 - 0.017 15.5 36.4 0.34 11.3 9.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Orf78 PF06024.12 GBG88818.1 - 0.075 13.3 2.9 6 7.2 0.6 2.4 2 0 0 2 2 2 0 Orf78 (ac78) RNase_H2_suC PF08615.11 GBG88818.1 - 0.18 12.0 3.8 4.9 7.3 3.5 2.5 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PBP1_TM PF14812.6 GBG88818.1 - 1.1 9.7 29.0 4.3 7.8 7.8 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CRA PF06589.11 GBG88818.1 - 8.3 6.5 6.5 1.8e+02 2.2 0.0 3.2 3 0 0 3 3 3 0 Circumsporozoite-related antigen (CRA) FAM176 PF14851.6 GBG88818.1 - 9.5 5.9 15.5 5.9 6.5 4.7 2.6 2 0 0 2 2 2 0 FAM176 family DUF1990 PF09348.10 GBG88819.1 - 1.1e-39 135.9 2.1 1.2e-23 83.8 0.2 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF1990) SARAF PF06682.12 GBG88819.1 - 0.002 17.8 1.7 0.054 13.2 0.0 2.2 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis CENP-B_dimeris PF09026.10 GBG88819.1 - 0.0075 16.6 35.9 0.2 12.0 8.6 2.4 2 0 0 2 2 2 2 Centromere protein B dimerisation domain Orf78 PF06024.12 GBG88819.1 - 0.045 14.0 2.9 4.6 7.6 0.6 2.4 2 0 0 2 2 2 0 Orf78 (ac78) RNase_H2_suC PF08615.11 GBG88819.1 - 0.093 12.9 3.8 0.41 10.8 0.0 2.5 1 1 1 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PBP1_TM PF14812.6 GBG88819.1 - 0.71 10.3 29.0 3.3 8.1 7.8 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SelK_SelG PF10961.8 GBG88819.1 - 2.8 8.6 8.5 4.8 7.9 7.3 2.0 1 1 0 1 1 1 0 Selenoprotein SelK_SelG CRA PF06589.11 GBG88819.1 - 3.9 7.6 6.6 1.4e+02 2.6 0.0 3.2 3 0 0 3 3 3 0 Circumsporozoite-related antigen (CRA) G-patch PF01585.23 GBG88820.1 - 8.2e-10 38.4 6.1 8.2e-10 38.4 6.1 2.0 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.8 GBG88820.1 - 1.4e-05 25.3 3.9 1.4e-05 25.3 3.9 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 GBG88820.1 - 0.0071 16.4 3.0 0.0071 16.4 3.0 2.1 2 0 0 2 2 2 1 G-patch domain zf-met PF12874.7 GBG88820.1 - 0.0075 16.6 0.7 0.013 15.9 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 GBG88820.1 - 0.014 15.5 3.7 0.024 14.8 3.7 1.4 1 0 0 1 1 1 0 DBF zinc finger Vac_ImportDeg PF09783.9 GBG88820.1 - 0.014 15.2 0.5 0.017 15.0 0.5 1.1 1 0 0 1 1 1 0 Vacuolar import and degradation protein UPF0054 PF02130.17 GBG88820.1 - 0.027 14.3 2.2 0.043 13.6 1.5 1.7 1 1 0 1 1 1 0 Uncharacterized protein family UPF0054 IL17R_fnIII_D2 PF16578.5 GBG88820.1 - 0.076 13.6 1.2 0.17 12.4 0.3 1.9 1 1 1 2 2 2 0 Interleukin 17 receptor D Spem1 PF15670.5 GBG88820.1 - 0.089 12.4 4.1 0.11 12.0 4.1 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 zf-C2H2 PF00096.26 GBG88820.1 - 0.11 13.1 0.6 0.2 12.2 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type bZIP_1 PF00170.21 GBG88821.1 - 0.061 13.4 2.9 0.11 12.6 0.7 2.5 2 0 0 2 2 2 0 bZIP transcription factor KASH_CCD PF14662.6 GBG88821.1 - 0.076 12.8 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SKG6 PF08693.10 GBG88821.1 - 2.3 7.7 3.4 5.3 6.5 3.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain bZIP_2 PF07716.15 GBG88821.1 - 2.7 8.2 6.8 3.3 7.9 0.6 2.9 2 0 0 2 2 2 0 Basic region leucine zipper PKcGMP_CC PF16808.5 GBG88821.1 - 7.7 6.5 6.4 1.2 9.0 0.9 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RVT_1 PF00078.27 GBG88822.1 - 1.2e-18 67.5 0.0 2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88822.1 - 1.9e-17 63.1 1.2 6.1e-17 61.5 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG88822.1 - 1.2e-07 31.9 0.0 2.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain CPBP PF02517.16 GBG88822.1 - 3.6e-07 30.5 2.3 9.8e-07 29.1 2.3 1.7 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease Chromo PF00385.24 GBG88822.1 - 0.03 14.2 0.1 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG88822.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase LMBR1 PF04791.16 GBG88823.1 - 0.0033 16.4 0.3 0.0047 15.9 0.3 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein LisH PF08513.11 GBG88823.1 - 0.11 12.5 0.2 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 LisH DUF1515 PF07439.11 GBG88823.1 - 0.37 10.8 10.7 0.63 10.1 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF659 PF04937.15 GBG88824.1 - 8.2e-19 68.0 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG88825.1 - 1.5e-30 105.1 0.1 3.3e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88825.1 - 2e-27 95.5 0.1 3.8e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AP1AR PF15745.5 GBG88825.1 - 0.022 14.4 1.9 0.037 13.7 1.9 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein SIP1 PF04938.12 GBG88825.1 - 0.069 12.9 0.4 0.34 10.6 0.1 2.2 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) RPW8 PF05659.11 GBG88826.1 - 0.13 11.9 0.6 0.36 10.5 0.6 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TPR_MLP1_2 PF07926.12 GBG88826.1 - 9 6.4 18.5 2.3 8.3 7.9 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein WD40 PF00400.32 GBG88827.1 - 3.5e-16 59.3 0.4 8.4e-07 29.6 0.2 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG88827.1 - 5.2e-06 26.7 0.0 0.022 15.0 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG88827.1 - 6e-05 22.2 0.2 0.15 11.0 0.1 2.1 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RRM_1 PF00076.22 GBG88828.1 - 3.4e-22 78.0 0.0 2.2e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_HEPA PF03324.14 GBG88828.1 - 0.18 12.3 0.0 27 5.3 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein RRM_1 PF00076.22 GBG88829.1 - 2.9e-22 78.3 0.0 2e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_HEPA PF03324.14 GBG88829.1 - 0.16 12.4 0.0 25 5.4 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein RRM_1 PF00076.22 GBG88830.1 - 2.8e-22 78.3 0.0 1.9e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_HEPA PF03324.14 GBG88830.1 - 0.14 12.6 0.0 25 5.4 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein Beta_helix PF13229.6 GBG88832.1 - 4.9e-09 36.2 1.3 4.2e-08 33.2 1.4 2.0 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG88832.1 - 5.1e-05 22.6 0.0 7.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 GBG88832.1 - 0.63 10.6 0.1 0.63 10.6 0.1 5.3 5 1 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RVT_1 PF00078.27 GBG88834.1 - 2.6e-25 89.2 0.0 3.8e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG88835.1 - 3.8e-19 69.0 0.0 5.2e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Beta_helix PF13229.6 GBG88836.1 - 3e-09 36.9 1.7 7.9e-09 35.6 1.1 1.9 1 1 0 1 1 1 1 Right handed beta helix region Beta_helix PF13229.6 GBG88837.1 - 2.7e-07 30.6 1.1 1.7e-06 28.0 1.0 2.0 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG88837.1 - 0.00022 20.6 0.2 0.0013 18.0 0.2 1.7 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 GBG88837.1 - 0.01 15.7 0.2 0.023 14.5 0.2 1.6 2 0 0 2 2 2 0 Pectate lyase superfamily protein Sugarporin_N PF11471.8 GBG88837.1 - 0.2 11.6 0.4 0.42 10.6 0.4 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Chlam_PMP PF02415.17 GBG88837.1 - 0.31 11.6 20.0 0.64 10.6 0.1 4.5 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat GTP1_OBG PF01018.22 GBG88837.1 - 0.83 9.2 6.0 7.6 6.1 0.6 2.5 2 0 0 2 2 2 0 GTP1/OBG F-box-like PF12937.7 GBG88838.1 - 1.5e-09 37.6 0.8 1.5e-09 37.6 0.8 2.9 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 GBG88838.1 - 2.3e-05 24.7 6.9 3.6 8.1 0.1 7.3 7 2 2 9 9 9 1 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG88838.1 - 0.00026 20.8 5.1 0.00039 20.2 0.8 3.1 3 0 0 3 3 3 1 F-box domain F-box_5 PF18511.1 GBG88838.1 - 0.0012 18.3 0.2 0.0029 17.1 0.2 1.6 1 0 0 1 1 1 1 F-box DUF1699 PF08004.11 GBG88838.1 - 0.011 15.4 0.0 0.6 9.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) Dimerisation2 PF16864.5 GBG88838.1 - 0.09 12.8 1.4 2 8.5 0.1 3.3 3 0 0 3 3 3 0 Dimerisation domain Mito_fiss_reg PF05308.11 GBG88838.1 - 0.16 12.0 2.1 0.28 11.3 2.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 GBG88838.1 - 1.5 8.2 9.6 2.9 7.3 9.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG88838.1 - 1.7 8.7 10.0 6.2 6.9 10.0 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 REV PF00424.18 GBG88841.1 - 0.16 12.0 1.8 0.82 9.7 0.1 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF3791 PF12668.7 GBG88843.1 - 0.2 11.7 0.1 0.63 10.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Myb_DNA-bind_4 PF13837.6 GBG88844.1 - 4.1e-10 39.9 2.5 4.1e-10 39.9 2.5 2.2 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG88844.1 - 0.0088 16.3 0.7 0.022 15.1 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG88844.1 - 0.3 11.2 6.3 0.12 12.5 3.1 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4667 PF15700.5 GBG88846.1 - 0.0084 16.2 0.6 0.0084 16.2 0.6 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF4667) Apt1 PF10351.9 GBG88846.1 - 0.076 11.9 26.7 0.69 8.7 1.5 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Myb_DNA-bind_4 PF13837.6 GBG88846.1 - 0.14 12.6 0.2 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SlyX PF04102.12 GBG88846.1 - 1.1 9.9 4.7 6.4 7.5 0.4 2.7 2 0 0 2 2 2 0 SlyX SURF2 PF05477.11 GBG88847.1 - 1.3 8.7 12.2 2 8.1 12.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 GBG88847.1 - 2.5 6.3 15.0 3.4 5.8 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG88847.1 - 3.6 6.2 11.8 4.9 5.8 11.8 1.2 1 0 0 1 1 1 0 Presenilin Gti1_Pac2 PF09729.9 GBG88847.1 - 4.5 7.3 11.9 6.9 6.7 11.9 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 GBG88847.1 - 7.2 5.5 12.4 11 5.0 12.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 AAA PF00004.29 GBG88848.1 - 8.3e-41 139.5 0.0 9.2e-37 126.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG88848.1 - 8.6e-09 35.1 1.3 2.2e-08 33.8 0.3 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 GBG88848.1 - 0.00021 21.7 1.5 0.0023 18.3 1.5 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GBG88848.1 - 0.0003 20.8 0.0 0.00093 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GBG88848.1 - 0.0022 17.9 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GBG88848.1 - 0.0042 16.8 0.1 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 GBG88848.1 - 0.0045 16.7 0.0 0.55 9.9 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_26 PF13500.6 GBG88848.1 - 0.065 13.0 0.1 3 7.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 GBG88848.1 - 0.074 13.2 0.4 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Torsin PF06309.11 GBG88848.1 - 0.099 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Torsin DUF4709 PF15821.5 GBG88849.1 - 2.2e-07 31.1 5.8 5.2e-07 29.9 2.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4709) Atg14 PF10186.9 GBG88849.1 - 2.3 7.2 7.8 3.1 6.8 6.8 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lzipper-MIP1 PF14389.6 GBG88849.1 - 4.6 7.6 9.0 0.28 11.5 3.0 2.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4407 PF14362.6 GBG88849.1 - 7.8 5.8 12.0 27 4.0 11.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 GBG88849.1 - 8.1 6.5 10.2 9.2 6.3 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 GBG88850.1 - 0.0066 16.7 1.6 0.01 16.1 0.2 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein PHB_depo_C PF06850.11 GBG88850.1 - 0.09 12.2 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 0 PHB de-polymerase C-terminus CENP-K PF11802.8 GBG88850.1 - 0.6 9.6 4.2 1.3 8.5 4.2 1.5 1 0 0 1 1 1 0 Centromere-associated protein K DUF812 PF05667.11 GBG88851.1 - 0.0063 15.4 9.9 0.0072 15.3 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ALMT PF11744.8 GBG88851.1 - 0.015 14.2 5.1 0.017 14.0 5.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MRP-S26 PF14943.6 GBG88851.1 - 0.015 15.3 15.5 0.02 14.8 15.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2205 PF10224.9 GBG88851.1 - 0.015 15.3 3.3 0.015 15.3 3.3 2.4 1 1 1 2 2 1 0 Short coiled-coil protein Vfa1 PF08432.10 GBG88851.1 - 0.17 12.2 11.0 0.22 11.9 11.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tho2 PF11262.8 GBG88851.1 - 0.51 9.5 6.6 0.69 9.1 6.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Presenilin PF01080.17 GBG88851.1 - 0.55 8.9 6.8 0.71 8.6 6.8 1.1 1 0 0 1 1 1 0 Presenilin U1snRNP70_N PF12220.8 GBG88851.1 - 0.64 10.7 10.2 1.5 9.5 10.2 1.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF913 PF06025.12 GBG88851.1 - 0.84 8.5 3.8 0.94 8.4 3.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 GBG88851.1 - 0.95 7.7 8.5 0.95 7.7 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GBG88851.1 - 1.1 9.0 11.3 1.6 8.5 11.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 GBG88851.1 - 1.2 6.9 4.3 1.3 6.8 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Selenoprotein_S PF06936.11 GBG88851.1 - 1.5 8.6 12.8 2.3 8.0 12.8 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DASH_Spc19 PF08287.11 GBG88851.1 - 1.6 8.6 16.8 3 7.7 16.8 1.4 1 0 0 1 1 1 0 Spc19 CorA PF01544.18 GBG88851.1 - 1.9 7.7 4.0 3.2 7.0 4.0 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TMPIT PF07851.13 GBG88851.1 - 4.1 6.5 7.0 4.8 6.3 7.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein MCU PF04678.13 GBG88851.1 - 4.4 7.4 7.4 6.4 6.8 7.4 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1682 PF07946.14 GBG88851.1 - 5.4 6.1 18.0 7.1 5.7 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Connexin PF00029.19 GBG88851.1 - 7 6.3 6.0 9.3 5.9 6.0 1.2 1 0 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 GBG88851.1 - 8.1 6.5 10.0 14 5.7 10.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FlxA PF14282.6 GBG88851.1 - 9.2 6.3 16.2 44 4.1 0.1 3.0 2 1 0 2 2 2 0 FlxA-like protein Plavaka PF18759.1 GBG88852.1 - 1.1e-26 93.9 0.4 1.6e-26 93.4 0.4 1.3 1 0 0 1 1 1 1 Plavaka transposase Peptidase_C48 PF02902.19 GBG88852.1 - 1.1e-07 31.9 0.2 2.3e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HSP20 PF00011.21 GBG88854.1 - 1.5e-22 79.7 0.0 2.2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG88854.1 - 3.2e-08 33.0 0.2 1e-07 31.4 0.1 1.8 2 1 0 2 2 2 1 HSP20-like domain found in ArsA HSP20 PF00011.21 GBG88856.1 - 3.3e-28 97.8 0.1 4.6e-28 97.3 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG88856.1 - 2.7e-08 33.2 0.1 6.4e-08 32.0 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 GBG88857.1 - 1.6e-26 92.4 0.1 3.1e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG88857.1 - 1.3e-06 27.8 0.1 4.5e-06 26.1 0.1 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 GBG88857.1 - 0.093 13.0 0.9 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 BON domain HSP20 PF00011.21 GBG88858.1 - 8.4e-28 96.5 0.2 1.2e-27 96.0 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG88858.1 - 6e-08 32.1 0.2 1.4e-07 30.9 0.2 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 GBG88859.1 - 1.8e-27 95.5 0.1 2.4e-27 95.1 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG88859.1 - 7.2e-08 31.9 0.1 1.6e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Myb_DNA-bind_4 PF13837.6 GBG88863.1 - 2.1e-06 28.0 0.3 4.1e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TMEM154 PF15102.6 GBG88863.1 - 0.19 11.7 0.9 0.37 10.7 0.9 1.4 1 0 0 1 1 1 0 TMEM154 protein family gag-asp_proteas PF13975.6 GBG88864.1 - 5.2e-07 30.1 0.1 1.1e-06 29.1 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88864.1 - 1.1e-05 26.0 0.1 2.1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88864.1 - 0.00033 20.5 0.1 0.00086 19.1 0.1 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG88864.1 - 0.0069 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DDE_Tnp_4 PF13359.6 GBG88865.1 - 2.2e-26 92.4 0.0 5.2e-25 88.0 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88865.1 - 8.2e-10 38.6 0.0 1.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88865.1 - 0.026 14.2 0.2 3.4 7.2 0.0 2.5 2 1 0 2 2 2 0 Transposase DDE domain DUF3483 PF11982.8 GBG88865.1 - 0.092 12.4 0.3 0.092 12.4 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) CCDC71L PF15374.6 GBG88866.1 - 0.028 13.7 5.7 0.054 12.8 5.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DUF659 PF04937.15 GBG88868.1 - 1.1e-12 48.1 0.1 2.1e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) FERM_f0 PF16511.5 GBG88869.1 - 4.3 7.7 12.5 13 6.2 0.8 4.3 1 1 3 4 4 4 0 N-terminal or F0 domain of Talin-head FERM gag-asp_proteas PF13975.6 GBG88870.1 - 4.4e-06 27.2 0.1 9.3e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88870.1 - 0.0002 21.9 0.1 0.00043 20.9 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88870.1 - 0.0078 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG88870.1 - 0.08 13.1 3.4 0.15 12.2 3.4 1.5 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 GBG88870.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DDE_Tnp_4 PF13359.6 GBG88871.1 - 2.6e-27 95.5 0.0 4.1e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88871.1 - 9.5e-19 67.8 0.0 1.3e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG88871.1 - 0.021 14.5 0.1 2.6 7.6 0.1 2.2 2 0 0 2 2 2 0 Transposase DDE domain Pkinase_Tyr PF07714.17 GBG88872.1 - 2.2e-11 43.6 0.0 3.5e-06 26.5 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase NHL PF01436.21 GBG88872.1 - 8e-07 28.8 0.1 0.038 14.0 0.1 3.4 2 0 0 2 2 2 2 NHL repeat Pkinase PF00069.25 GBG88872.1 - 0.00013 21.4 0.0 0.1 12.0 0.0 3.8 3 1 0 3 3 3 1 Protein kinase domain SGL PF08450.12 GBG88872.1 - 0.00082 19.0 0.0 1.3 8.6 0.0 2.3 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF2052 PF09747.9 GBG88872.1 - 0.4 10.8 30.7 0.27 11.3 1.5 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.16 GBG88872.1 - 1.3 9.0 13.0 9.8 6.2 2.4 4.2 4 0 0 4 4 4 0 Neurotransmitter-gated ion-channel transmembrane region RXT2_N PF08595.11 GBG88872.1 - 7.2 6.6 21.6 15 5.6 13.1 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Bestrophin PF01062.21 GBG88873.1 - 3.9e-06 26.5 0.1 8.7e-06 25.3 0.0 1.5 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel RVT_1 PF00078.27 GBG88874.1 - 4.8e-10 39.3 0.0 9.2e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG88874.1 - 0.00014 22.3 0.1 0.00032 21.2 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88874.1 - 0.0038 17.8 0.1 0.0076 16.9 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG88874.1 - 0.035 13.9 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Bestrophin PF01062.21 GBG88875.1 - 6.4e-13 48.7 0.2 4.3e-12 46.0 0.2 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RVT_1 PF00078.27 GBG88876.1 - 2e-24 86.4 0.0 2.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88876.1 - 7.3e-24 83.7 0.0 2.9e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88876.1 - 5.4e-18 65.2 0.0 2.6e-17 63.0 0.0 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG88876.1 - 7.2e-08 33.0 0.0 1.5e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88876.1 - 1.1e-06 29.1 0.0 2.7e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG88876.1 - 3e-06 27.0 0.0 7e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88876.1 - 0.00018 21.3 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease AI-2E_transport PF01594.16 GBG88879.1 - 2e-08 33.8 13.4 2e-08 33.8 13.4 3.1 3 0 0 3 3 3 2 AI-2E family transporter CemA PF03040.14 GBG88879.1 - 6.5 6.6 7.3 6.2 6.7 5.1 2.1 2 0 0 2 2 2 0 CemA family NOT2_3_5 PF04153.18 GBG88880.1 - 3.9e-17 62.6 5.0 1.2e-16 61.0 5.0 1.6 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Not3 PF04065.15 GBG88881.1 - 1.4e-13 50.8 0.6 2.3e-13 50.1 0.6 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Not3 PF04065.15 GBG88882.1 - 8.5e-54 182.4 17.5 9.3e-54 182.3 17.5 1.0 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Takusan PF04822.13 GBG88882.1 - 0.044 13.7 0.6 0.044 13.7 0.6 2.6 3 0 0 3 3 3 0 Takusan Prefoldin PF02996.17 GBG88882.1 - 0.11 12.4 0.2 0.11 12.4 0.2 3.7 3 1 1 4 4 4 0 Prefoldin subunit Glyco_hydro_67C PF07477.12 GBG88882.1 - 0.12 11.8 1.5 0.19 11.3 1.5 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus T3SS_needle_E PF08988.10 GBG88882.1 - 0.49 10.6 4.6 0.57 10.4 0.1 3.1 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle FAP206 PF12018.8 GBG88882.1 - 0.68 9.4 8.5 0.3 10.6 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function Lant_dehydr_C PF14028.6 GBG88882.1 - 0.87 9.1 5.5 1.1 8.7 5.3 1.3 1 1 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term FbpA PF05833.11 GBG88882.1 - 0.92 8.2 12.3 1.2 7.8 12.3 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4404 PF14357.6 GBG88882.1 - 1.3 9.7 6.3 1.9 9.1 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) MerR-DNA-bind PF09278.11 GBG88882.1 - 1.5 9.4 6.1 18 6.0 0.6 2.6 2 1 0 2 2 2 0 MerR, DNA binding DUF2203 PF09969.9 GBG88882.1 - 3.8 8.2 10.6 2.1 9.1 2.6 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.11 GBG88882.1 - 8.9 6.4 10.0 0.94 9.6 2.3 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NAD_binding_10 PF13460.6 GBG88884.1 - 1.3e-27 96.9 0.0 2.7e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding CIA30 PF08547.12 GBG88884.1 - 5.6e-21 75.2 0.0 9.8e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NmrA PF05368.13 GBG88884.1 - 8.6e-10 38.6 0.2 4.8e-07 29.6 0.2 2.4 2 1 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 GBG88884.1 - 0.0012 18.4 0.0 0.015 14.8 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GBG88884.1 - 0.0026 17.2 0.2 0.004 16.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.20 GBG88884.1 - 0.035 14.2 1.5 0.074 13.2 0.2 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 GBG88884.1 - 0.064 12.3 0.1 1.9 7.5 0.1 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 GBG88884.1 - 0.19 10.9 0.2 17 4.5 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Pkinase PF00069.25 GBG88885.1 - 1.9e-76 256.9 0.0 3.4e-76 256.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 GBG88885.1 - 8.9e-33 109.4 3.1 4.5e-08 32.1 0.0 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.17 GBG88885.1 - 2.4e-29 102.4 0.0 5.3e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 GBG88885.1 - 5.1e-28 97.3 1.2 7.8e-13 48.7 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG88885.1 - 2.6e-25 86.2 1.4 8.4e-06 25.3 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GBG88885.1 - 3.2e-23 80.1 0.7 4.8e-06 25.8 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GBG88885.1 - 2.5e-19 68.9 5.4 1.6e-07 31.1 0.8 4.1 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 GBG88885.1 - 3.3e-09 36.6 0.3 0.0041 17.1 0.0 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GBG88885.1 - 3.4e-06 27.3 3.6 0.0062 16.8 0.3 3.2 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GBG88885.1 - 1.1e-05 25.7 0.1 0.096 13.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.14 GBG88885.1 - 2.5e-05 23.7 0.4 6.4e-05 22.4 0.4 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Dockerin_1 PF00404.18 GBG88885.1 - 0.00021 21.4 0.1 1.5 9.0 0.0 3.4 3 0 0 3 3 3 1 Dockerin type I domain Kinase-like PF14531.6 GBG88885.1 - 0.00029 20.2 0.0 0.0091 15.3 0.0 2.2 1 1 0 2 2 2 1 Kinase-like EFhand_Ca_insen PF08726.10 GBG88885.1 - 0.0061 16.6 0.1 1.9 8.7 0.0 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand APH PF01636.23 GBG88885.1 - 0.0097 15.8 0.2 3.4 7.5 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Toprim_2 PF13155.6 GBG88885.1 - 0.052 14.0 0.1 3.5 8.1 0.0 3.3 1 1 2 3 3 3 0 Toprim-like DUF5580 PF17743.1 GBG88885.1 - 0.065 11.8 1.4 0.5 8.8 0.0 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5580) PMBR PF09373.10 GBG88885.1 - 0.077 13.2 0.1 41 4.6 0.0 3.3 3 0 0 3 3 3 0 Pseudomurein-binding repeat DUF4589 PF15252.6 GBG88885.1 - 0.079 13.0 3.9 0.14 12.2 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) DUF2722 PF10846.8 GBG88885.1 - 0.26 10.2 4.4 0.39 9.6 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 GBG88885.1 - 0.3 9.4 9.7 0.42 8.8 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG88885.1 - 0.32 10.3 12.5 0.79 9.0 12.5 1.6 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GBG88885.1 - 0.98 7.6 18.1 1.3 7.1 18.1 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 GBG88885.1 - 1.4 8.6 6.4 3.9 7.1 6.4 1.7 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 GBG88885.1 - 7.1 5.7 8.2 15 4.6 8.2 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ELO PF01151.18 GBG88886.1 - 2.1e-50 171.6 19.6 2.6e-50 171.3 19.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PHB_depo_C PF06850.11 GBG88886.1 - 0.035 13.6 0.1 0.052 13.0 0.1 1.2 1 0 0 1 1 1 0 PHB de-polymerase C-terminus Mad3_BUB1_I PF08311.12 GBG88887.1 - 1.1e-34 119.1 0.7 2.4e-34 118.0 0.7 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 GBG88887.1 - 3.8e-11 42.9 1.5 4.2e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_I_2 PF17014.5 GBG88887.1 - 0.0001 22.4 0.4 0.00023 21.3 0.4 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein TRAP_alpha PF03896.16 GBG88887.1 - 0.092 11.9 12.1 0.046 12.9 4.7 2.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit PI3K_C2 PF00792.24 GBG88887.1 - 8.6 6.3 10.4 45 3.9 0.2 2.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 Annexin PF00191.20 GBG88888.1 - 9.4e-39 131.3 0.0 3.5e-15 55.8 0.0 4.3 4 0 0 4 4 4 4 Annexin RVT_1 PF00078.27 GBG88890.1 - 2.7e-12 46.7 0.0 3.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG88891.1 - 2.2e-06 27.9 0.3 5e-06 26.8 0.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG88891.1 - 0.00068 19.7 0.8 0.002 18.2 0.8 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CTP_transf_like PF01467.26 GBG88891.1 - 0.12 12.5 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Cytidylyltransferase-like CAP PF00188.26 GBG88893.1 - 1.5e-21 77.5 0.7 1.9e-21 77.2 0.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RVT_1 PF00078.27 GBG88894.1 - 2.1e-06 27.4 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RXLR PF16810.5 GBG88894.1 - 0.31 11.5 3.3 0.32 11.4 0.9 2.2 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Integrase_H2C2 PF17921.1 GBG88895.1 - 2.1e-14 53.4 0.3 4.1e-14 52.4 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG88895.1 - 0.022 14.9 0.7 0.041 14.1 0.7 1.5 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG88896.1 - 8.4e-22 77.4 0.0 1.9e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88896.1 - 9.8e-21 73.7 0.0 1.8e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88896.1 - 8.9e-19 67.8 0.0 3.8e-18 65.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG88896.1 - 2.1e-16 59.7 0.3 4.8e-16 58.6 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG88896.1 - 1.4e-09 37.8 0.0 2.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG88896.1 - 3e-06 27.8 0.2 1.2e-05 25.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88896.1 - 0.00014 22.3 0.5 0.00035 21.1 0.1 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88896.1 - 0.012 15.4 0.3 0.026 14.3 0.3 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG88896.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Histone PF00125.24 GBG88897.1 - 3.8e-19 69.3 0.1 3.8e-19 69.3 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 zf-U11-48K PF05253.12 GBG88897.1 - 0.16 11.9 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger CENP-S PF15630.6 GBG88897.1 - 0.18 12.2 0.4 0.46 10.9 0.4 1.6 1 0 0 1 1 1 0 CENP-S protein Myb_DNA-bind_4 PF13837.6 GBG88899.1 - 2.1e-06 28.0 0.3 5e-06 26.8 0.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG88899.1 - 0.00067 19.7 0.8 0.002 18.2 0.8 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CTP_transf_like PF01467.26 GBG88899.1 - 0.12 12.6 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Cytidylyltransferase-like DUF1635 PF07795.11 GBG88900.1 - 0.33 10.8 1.3 0.94 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Ubiq_cyt_C_chap PF03981.12 GBG88902.1 - 1.7e-30 105.9 0.2 2.9e-30 105.2 0.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone RVT_1 PF00078.27 GBG88903.1 - 1.8e-29 102.9 0.0 3.1e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88903.1 - 1.5e-18 66.6 0.1 3.3e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88903.1 - 5.5e-16 58.8 0.0 1.4e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG88903.1 - 0.0022 18.2 0.0 0.008 16.4 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG88903.1 - 0.0059 16.9 0.4 0.022 15.0 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF1564 PF07600.11 GBG88903.1 - 0.0099 15.6 0.0 0.032 13.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) DUF5066 PF16728.5 GBG88903.1 - 0.019 14.3 0.1 0.065 12.6 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5066) gag-asp_proteas PF13975.6 GBG88903.1 - 0.023 15.2 0.0 0.068 13.7 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG88904.1 - 2.5e-27 95.8 0.3 6.7e-27 94.5 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG88904.1 - 0.0037 17.2 0.0 0.014 15.3 0.0 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HIP1_clath_bdg PF16515.5 GBG88904.1 - 0.0067 17.0 6.0 0.0067 17.0 6.0 2.9 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Retrotrans_gag PF03732.17 GBG88904.1 - 0.033 14.4 0.1 0.033 14.4 0.1 3.8 4 0 0 4 4 4 0 Retrotransposon gag protein BLOC1_2 PF10046.9 GBG88904.1 - 0.036 14.4 5.4 0.15 12.3 4.0 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BBS2_C PF14782.6 GBG88904.1 - 0.1 11.3 0.8 6.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DivIC PF04977.15 GBG88904.1 - 0.15 11.8 6.3 0.77 9.6 4.4 3.1 2 0 0 2 2 2 0 Septum formation initiator DUF2959 PF11172.8 GBG88904.1 - 0.46 10.6 6.9 0.15 12.2 2.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) SlyX PF04102.12 GBG88904.1 - 0.7 10.5 9.3 0.6 10.8 5.8 2.8 2 0 0 2 2 2 0 SlyX LCD1 PF09798.9 GBG88904.1 - 1.4 7.3 3.3 2.5 6.5 3.3 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein RT_RNaseH PF17917.1 GBG88905.1 - 2.7e-23 82.2 0.0 5.1e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88905.1 - 2.6e-22 78.8 0.0 5.3e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88905.1 - 6.9e-13 48.6 0.1 1.9e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG88905.1 - 4.2e-06 26.6 0.0 1.7e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88905.1 - 6.6e-06 26.7 0.0 3.8e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88905.1 - 8.1e-06 26.3 0.0 0.0016 18.9 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 GBG88905.1 - 0.0025 17.7 1.7 0.0055 16.6 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 GBG88905.1 - 0.016 15.0 0.0 0.068 13.0 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC PF00098.23 GBG88905.1 - 1.6 8.9 4.7 3.5 7.9 4.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG88906.1 - 0.006 16.8 0.7 0.017 15.4 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF659 PF04937.15 GBG88909.1 - 2.7e-19 69.5 0.0 4.5e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SLIDE PF09111.10 GBG88909.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 SLIDE RVT_1 PF00078.27 GBG88911.1 - 3.6e-30 105.2 0.2 4.8e-30 104.7 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88911.1 - 1.3e-11 44.4 0.0 2.8e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88911.1 - 1.5e-05 25.3 0.0 2.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase S6PP_C PF08472.10 GBG88911.1 - 0.1 12.4 0.0 13 5.7 0.0 2.9 2 1 1 3 3 3 0 Sucrose-6-phosphate phosphohydrolase C-terminal RVT_1 PF00078.27 GBG88912.1 - 1.7e-08 34.2 0.0 5.6e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG88912.1 - 1.2e-07 32.2 0.0 5.8e-07 30.1 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88912.1 - 1.1e-06 28.4 0.0 3.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88912.1 - 2e-05 25.1 0.5 0.00015 22.2 0.0 2.9 4 0 0 4 4 4 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG88912.1 - 0.0077 16.5 8.1 0.03 14.6 0.0 3.8 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG88912.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease NUDIX PF00293.28 GBG88913.1 - 4.9e-21 75.1 0.0 7.1e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RNase_HII PF01351.18 GBG88913.1 - 0.091 12.6 0.0 3.2 7.5 0.0 2.3 2 1 0 2 2 2 0 Ribonuclease HII gag-asp_proteas PF13975.6 GBG88914.1 - 2.1e-05 25.0 0.1 5.7e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88914.1 - 0.0003 21.4 0.1 0.00092 19.8 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88914.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88914.1 - 0.0087 15.9 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG88914.1 - 0.036 14.1 1.9 0.064 13.4 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG88914.1 - 0.094 12.4 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Integrase_H2C2 PF17921.1 GBG88915.1 - 1.1e-17 63.8 0.1 2.8e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG88915.1 - 9.2e-09 35.1 0.0 1.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG88915.1 - 2e-08 34.8 0.1 1.5e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88915.1 - 1.3e-07 32.0 0.3 6.2e-07 29.9 0.1 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG88915.1 - 6.7e-07 29.5 0.0 2e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG88915.1 - 2.6e-05 24.0 0.3 7.2e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GBG88915.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF659 PF04937.15 GBG88916.1 - 6.1e-16 58.6 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG88917.1 - 1.2e-57 192.1 0.0 7.4e-29 99.7 0.0 3.7 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88917.1 - 7.8e-55 183.6 0.0 2.9e-27 95.0 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88917.1 - 5.9e-32 109.6 6.3 6.5e-19 67.8 0.5 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG88917.1 - 4.3e-27 95.1 0.0 8.1e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG88917.1 - 7.7e-05 22.8 2.6 0.0031 17.7 0.1 2.9 2 0 0 2 2 2 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG88918.1 - 1.4e-27 95.6 0.0 2.4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88918.1 - 5.3e-25 87.7 0.0 1.1e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88918.1 - 1.3e-10 41.2 0.1 1.9e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG88918.1 - 1.7 6.9 8.8 2.2 6.5 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG88918.1 - 1.8 7.9 10.3 2.3 7.6 10.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG88918.1 - 6.2 4.9 12.6 8.1 4.5 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family FAM60A PF15396.6 GBG88919.1 - 0.45 10.5 14.1 0.67 9.9 14.1 1.4 1 1 0 1 1 1 0 Protein Family FAM60A LMBR1 PF04791.16 GBG88919.1 - 1.4 7.8 2.3 1.7 7.5 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DDHD PF02862.17 GBG88919.1 - 2.4 8.3 5.8 3.2 7.8 5.8 1.2 1 0 0 1 1 1 0 DDHD domain CSRNP_N PF16019.5 GBG88919.1 - 6.4 6.6 12.7 0.72 9.7 7.6 1.8 1 1 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus RVT_1 PF00078.27 GBG88920.1 - 2.8e-37 128.4 0.0 4.8e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88920.1 - 4.6e-31 106.8 0.0 1.1e-30 105.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88920.1 - 1.7e-30 105.4 0.0 3.3e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG88920.1 - 0.037 13.7 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Yop-YscD_ppl PF16693.5 GBG88920.1 - 0.15 11.5 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Inner membrane component of T3SS, periplasmic domain Asp_protease_2 PF13650.6 GBG88921.1 - 0.00069 20.2 0.0 0.0018 18.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88921.1 - 0.0014 19.2 0.2 0.0043 17.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG88921.1 - 0.0056 16.7 2.2 0.012 15.7 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG88921.1 - 0.0061 16.8 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein NeA_P2 PF12312.8 GBG88921.1 - 0.17 11.3 2.4 0.39 10.1 2.4 1.6 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein DUF685 PF05085.12 GBG88922.1 - 0.096 12.0 0.0 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF685) zf-CCHC PF00098.23 GBG88923.1 - 0.00096 19.1 1.0 0.0016 18.5 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle YqfQ PF14181.6 GBG88923.1 - 0.59 10.3 4.0 1.1 9.4 4.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein XRN_M PF17846.1 GBG88923.1 - 4.1 6.2 7.9 5.8 5.7 7.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain RR_TM4-6 PF06459.12 GBG88923.1 - 5.4 6.8 14.4 0.94 9.2 9.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG88924.1 - 0.00068 19.2 60.5 0.0012 18.4 60.5 1.4 1 0 0 1 1 1 1 SDA1 Fis1_TPR_C PF14853.6 GBG88924.1 - 0.00085 19.3 0.2 0.0017 18.4 0.2 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Macoilin PF09726.9 GBG88924.1 - 8.6 4.8 9.9 11 4.4 9.9 1.2 1 0 0 1 1 1 0 Macoilin family DNase-RNase PF02577.14 GBG88925.1 - 1.1e-21 76.8 0.0 2e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.19 GBG88925.1 - 0.0064 16.2 1.2 0.012 15.3 1.2 1.5 1 0 0 1 1 1 1 UvrB/uvrC motif DNase-RNase PF02577.14 GBG88926.1 - 1e-21 76.9 0.0 1.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.19 GBG88926.1 - 0.0062 16.2 1.2 0.012 15.3 1.2 1.5 1 0 0 1 1 1 1 UvrB/uvrC motif DUF659 PF04937.15 GBG88928.1 - 1.5e-32 112.6 0.1 2.2e-32 112.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG88928.1 - 1.7e-05 24.5 0.3 3.2e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FYVE PF01363.21 GBG88928.1 - 0.18 12.0 1.2 0.44 10.7 1.2 1.6 1 0 0 1 1 1 0 FYVE zinc finger mTERF PF02536.14 GBG88929.1 - 4.2e-77 259.1 2.1 1.3e-59 201.7 0.6 2.2 1 1 1 2 2 2 2 mTERF Sigma70_ner PF04546.13 GBG88929.1 - 0.0066 16.4 14.9 0.028 14.3 14.9 2.0 2 0 0 2 2 2 1 Sigma-70, non-essential region NOA36 PF06524.12 GBG88929.1 - 0.022 14.1 18.9 0.04 13.2 18.9 1.4 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 GBG88929.1 - 0.035 14.0 2.4 0.082 12.8 2.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region CobT PF06213.12 GBG88929.1 - 0.042 13.2 13.7 0.07 12.5 13.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.9 GBG88929.1 - 0.18 10.9 31.9 0.33 10.1 31.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 GBG88929.1 - 0.26 9.5 20.8 0.38 8.9 20.8 1.1 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 GBG88929.1 - 0.27 11.2 26.1 0.47 10.4 26.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 GBG88929.1 - 0.88 8.9 23.6 1.4 8.3 23.6 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG88929.1 - 1.1 7.4 20.2 1.7 6.8 20.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG88929.1 - 2.2 6.3 33.9 3 5.8 33.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 GBG88929.1 - 2.7 7.6 28.1 4.6 6.9 28.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mpp10 PF04006.12 GBG88929.1 - 3 6.2 19.3 4.4 5.6 19.3 1.1 1 0 0 1 1 1 0 Mpp10 protein PPP4R2 PF09184.11 GBG88929.1 - 3.2 7.3 21.5 5.2 6.6 21.5 1.2 1 0 0 1 1 1 0 PPP4R2 zf-CCHC_3 PF13917.6 GBG88930.1 - 0.0003 20.7 0.9 0.00068 19.5 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG88930.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG88930.1 - 1.5 9.1 3.7 2.5 8.3 3.7 1.4 1 0 0 1 1 1 0 Zinc knuckle PHD_Oberon PF07227.11 GBG88931.1 - 4.8e-13 49.1 9.8 5.3e-07 29.6 0.3 2.4 2 0 0 2 2 2 2 PHD - plant homeodomain finger protein MBD PF01429.19 GBG88931.1 - 0.0019 17.9 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain Retrotrans_gag PF03732.17 GBG88932.1 - 3e-15 56.3 0.5 5e-15 55.6 0.5 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 GBG88932.1 - 0.00021 21.2 0.3 0.0004 20.3 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG88932.1 - 0.00081 19.0 0.6 0.0018 17.9 0.6 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG88932.1 - 0.1 12.5 0.4 0.19 11.6 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG88932.1 - 0.37 10.6 1.9 0.63 9.8 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle FBPase PF00316.20 GBG88933.1 - 7e-53 178.9 0.0 1e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DnaJ_CXXCXGXG PF00684.19 GBG88934.1 - 3.2e-05 24.2 0.7 0.064 13.6 0.4 2.5 2 0 0 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 GBG88934.1 - 6.9 6.7 7.3 7.9 6.5 0.0 2.9 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein CorA PF01544.18 GBG88935.1 - 1.4e-07 31.2 0.4 1.4e-07 31.2 0.4 2.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SpoIIIAH PF12685.7 GBG88935.1 - 0.00019 21.4 11.3 0.00019 21.4 11.3 4.6 4 1 0 4 4 2 1 SpoIIIAH-like protein Zip PF02535.22 GBG88935.1 - 0.0025 17.1 5.9 0.0025 17.1 5.9 4.3 4 1 0 4 4 3 1 ZIP Zinc transporter Plasmodium_Vir PF05795.11 GBG88935.1 - 0.0066 15.9 1.3 0.0066 15.9 1.3 4.4 4 0 0 4 4 4 1 Plasmodium vivax Vir protein CLN3 PF02487.17 GBG88935.1 - 0.035 13.2 0.0 0.035 13.2 0.0 3.8 3 0 0 3 3 2 0 CLN3 protein DUF3169 PF11368.8 GBG88935.1 - 0.071 12.6 0.1 0.27 10.7 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF2681 PF10883.8 GBG88935.1 - 0.074 13.5 0.1 0.074 13.5 0.1 5.7 5 1 1 6 6 2 0 Protein of unknown function (DUF2681) Phage_holin_3_6 PF07332.11 GBG88935.1 - 0.097 12.7 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF202 PF02656.15 GBG88935.1 - 0.11 13.0 1.8 0.3 11.6 1.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF202) LapA_dom PF06305.11 GBG88935.1 - 0.15 11.9 0.0 0.15 11.9 0.0 3.6 4 0 0 4 4 2 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 GBG88935.1 - 0.76 10.7 6.6 34 5.4 0.0 4.5 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain SET PF00856.28 GBG88936.1 - 3.5e-19 69.8 0.1 1.4e-18 67.8 0.1 2.2 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 GBG88936.1 - 1.4e-11 45.0 0.7 1.4e-11 45.0 0.7 3.7 5 0 0 5 5 5 1 Pre-SET motif zf-HC5HC2H PF13771.6 GBG88936.1 - 2.3e-06 27.8 7.4 2.3e-06 27.8 7.4 3.1 4 0 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GBG88936.1 - 6.2e-05 23.1 4.4 6.2e-05 23.1 4.4 3.2 4 0 0 4 4 4 1 PHD-zinc-finger like domain RVT_1 PF00078.27 GBG88937.1 - 2.3e-28 99.2 0.0 3.8e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88937.1 - 1.9e-18 66.3 0.0 7.2e-13 48.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG88937.1 - 4.9e-12 45.6 0.0 1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG88937.1 - 2.5e-08 34.1 0.0 5.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG88938.1 - 0.00012 22.3 0.2 0.00037 20.7 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2781 PF10914.8 GBG88938.1 - 0.016 15.6 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) RT_RNaseH_2 PF17919.1 GBG88939.1 - 7.9e-33 112.5 0.0 2.7e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88939.1 - 2.5e-29 101.7 0.1 4.6e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88939.1 - 9.8e-15 54.8 0.0 2.8e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG88939.1 - 3.9e-07 30.5 0.0 1.3e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88939.1 - 9.7e-05 22.9 0.0 0.00023 21.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG88939.1 - 0.0088 16.1 0.2 0.019 15.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1758 PF05585.12 GBG88939.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG88939.1 - 0.028 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease TP_methylase PF00590.20 GBG88939.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases RT_RNaseH_2 PF17919.1 GBG88940.1 - 6.8e-66 218.6 0.5 2e-31 108.0 0.1 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88940.1 - 3.2e-50 168.8 0.3 1.8e-28 98.9 0.1 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88940.1 - 3.3e-36 124.9 0.6 1.1e-30 106.8 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG88940.1 - 9.4e-19 67.6 0.0 2.6e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 GBG88940.1 - 3.1e-17 62.9 0.1 1.2e-16 61.0 0.1 2.0 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG88940.1 - 5.5e-17 61.6 0.1 1.5e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Plant_tran PF04827.14 GBG88940.1 - 1.5e-06 28.0 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Retrotrans_gag PF03732.17 GBG88940.1 - 0.00029 21.0 3.3 0.23 11.8 0.0 3.4 3 0 0 3 3 3 2 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG88940.1 - 0.00044 20.2 8.6 0.061 13.3 1.7 2.6 2 0 0 2 2 2 2 Zinc knuckle FtsK_4TM PF13491.6 GBG88940.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE DUF3863 PF12979.7 GBG88940.1 - 0.14 11.0 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Rrn6 PF10214.9 GBG88940.1 - 2.2 6.7 26.9 0.045 12.3 8.5 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor zf-CCHC_4 PF14392.6 GBG88940.1 - 6.8 6.5 8.5 2.7 7.8 0.9 2.8 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG88941.1 - 6.6e-66 218.6 0.5 2e-31 108.0 0.1 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88941.1 - 3e-50 168.9 0.3 1.7e-28 98.9 0.1 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88941.1 - 3.2e-36 124.9 0.6 1.1e-30 106.8 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG88941.1 - 9.6e-19 67.6 0.0 2.5e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 GBG88941.1 - 3e-17 62.9 0.1 1.2e-16 61.0 0.1 2.0 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG88941.1 - 5.6e-17 61.6 0.1 1.5e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Plant_tran PF04827.14 GBG88941.1 - 1.5e-06 28.0 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein Retrotrans_gag PF03732.17 GBG88941.1 - 0.00032 20.9 3.3 0.23 11.8 0.0 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein zf-CCHC_3 PF13917.6 GBG88941.1 - 0.00043 20.2 8.6 0.061 13.3 1.7 2.6 2 0 0 2 2 2 2 Zinc knuckle FtsK_4TM PF13491.6 GBG88941.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE Rrn6 PF10214.9 GBG88941.1 - 2.2 6.7 26.9 0.045 12.3 8.5 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor zf-CCHC_4 PF14392.6 GBG88941.1 - 6.7 6.5 8.5 2.7 7.8 0.9 2.8 2 0 0 2 2 2 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG88942.1 - 5.5e-09 36.3 0.3 1.4e-08 35.0 0.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH PF17917.1 GBG88943.1 - 5.4e-30 103.8 1.5 3.4e-26 91.6 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88943.1 - 5.4e-30 103.4 0.0 1.3e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88943.1 - 1.4e-26 93.4 0.2 4.2e-26 91.8 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88943.1 - 3.6e-11 43.0 0.0 1e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1758 PF05585.12 GBG88943.1 - 0.052 13.3 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG88943.1 - 0.06 13.9 0.0 0.18 12.4 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ribosomal_S3_C PF00189.20 GBG88944.1 - 0.15 12.6 0.1 0.45 11.1 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain zf-CCHC PF00098.23 GBG88945.1 - 2.4e-05 24.2 1.3 4.6e-05 23.3 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG88945.1 - 0.00094 18.8 1.3 0.0021 17.7 1.3 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Olfactory_mark PF06554.12 GBG88945.1 - 0.088 12.6 2.7 0.15 11.8 2.7 1.3 1 0 0 1 1 1 0 Olfactory marker protein zf-CCHC_4 PF14392.6 GBG88945.1 - 0.11 12.2 0.4 0.24 11.2 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle ATP-synt_C PF00137.21 GBG88946.1 - 3.5e-26 91.3 33.7 3.3e-15 56.2 13.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.24 GBG88946.1 - 8.1 6.1 11.2 0.47 10.1 0.5 2.9 1 1 2 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L COMPASS-Shg1 PF05205.12 GBG88947.1 - 0.031 15.0 1.0 0.031 15.0 1.0 1.7 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 RT_RNaseH_2 PF17919.1 GBG88949.1 - 8.8e-24 83.4 0.0 5.6e-23 80.9 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88949.1 - 9.4e-24 84.1 0.1 1.9e-23 83.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88949.1 - 1.7e-21 76.5 0.0 4e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ABC_tran PF00005.27 GBG88949.1 - 2e-15 57.5 0.0 1.7e-06 28.6 0.0 3.3 2 1 0 2 2 2 2 ABC transporter MMADHC PF10229.9 GBG88949.1 - 7.1e-10 39.1 0.0 1.6e-06 28.1 0.0 2.8 3 0 0 3 3 3 2 Methylmalonic aciduria and homocystinuria type D protein AAA_16 PF13191.6 GBG88949.1 - 3.2e-05 24.4 2.3 0.004 17.6 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 GBG88949.1 - 0.00012 22.7 0.1 0.0003 21.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain ABC_membrane_2 PF06472.15 GBG88949.1 - 0.00039 19.9 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Rad17 PF03215.15 GBG88949.1 - 0.006 16.5 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 GBG88949.1 - 0.0069 16.8 0.0 0.022 15.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 GBG88949.1 - 0.017 14.9 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Retrotrans_gag PF03732.17 GBG88949.1 - 0.045 14.0 0.3 0.17 12.1 0.1 2.2 2 0 0 2 2 1 0 Retrotransposon gag protein Mg_chelatase PF01078.21 GBG88949.1 - 0.11 11.9 0.3 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 GBG88949.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Rtf2 PF04641.12 GBG88949.1 - 0.12 11.7 4.0 0.27 10.6 4.0 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger AAA_22 PF13401.6 GBG88949.1 - 0.14 12.4 1.4 0.45 10.8 0.3 2.4 2 0 0 2 2 2 0 AAA domain SlyX PF04102.12 GBG88949.1 - 2 9.1 6.7 0.61 10.8 0.7 3.2 3 0 0 3 3 3 0 SlyX ADIP PF11559.8 GBG88950.1 - 0.0011 19.1 9.7 0.0011 19.1 9.7 2.7 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 GBG88950.1 - 0.0033 17.5 5.0 0.0033 17.5 5.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF5069 PF16798.5 GBG88950.1 - 0.0059 16.8 2.2 0.026 14.7 0.3 2.8 2 1 0 3 3 3 1 Domain of unknown function (DUF5069) PEP-utilisers_N PF05524.13 GBG88950.1 - 0.0077 16.4 5.4 0.0077 16.4 5.4 1.9 2 1 0 2 2 2 1 PEP-utilising enzyme, N-terminal FUSC PF04632.12 GBG88950.1 - 0.22 10.0 4.7 0.31 9.5 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Erythro_esteras PF05139.14 GBG88950.1 - 5.1 6.8 9.9 1.5 8.6 6.9 1.6 1 1 1 2 2 2 0 Erythromycin esterase DUF1501 PF07394.12 GBG88951.1 - 0.66 9.0 3.7 1.2 8.1 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) UPF0515 PF15135.6 GBG88951.1 - 3 7.1 10.6 0.24 10.7 5.6 1.6 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 MCM3AP_GANP PF16769.5 GBG88951.1 - 5.8 5.0 8.4 8.5 4.5 8.4 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP SlyX PF04102.12 GBG88952.1 - 0.012 16.2 1.7 0.012 16.2 1.7 3.3 2 2 1 3 3 3 0 SlyX DNA_Packaging PF11053.8 GBG88952.1 - 0.023 14.5 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 Terminase DNA packaging enzyme DUF2730 PF10805.8 GBG88952.1 - 0.034 14.2 0.7 0.22 11.6 0.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) CorA PF01544.18 GBG88952.1 - 0.035 13.4 0.3 0.035 13.4 0.3 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein TolA_bind_tri PF16331.5 GBG88952.1 - 3.4 7.8 11.1 3.8 7.7 5.5 2.8 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF3391 PF11871.8 GBG88952.1 - 4.7 7.8 7.9 2.4 8.7 5.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Spore_coat_CotO PF14153.6 GBG88952.1 - 6 6.7 9.5 1 9.3 5.3 1.8 2 0 0 2 2 2 0 Spore coat protein CotO RT_RNaseH_2 PF17919.1 GBG88953.1 - 2.2e-22 78.9 0.0 4.8e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88953.1 - 2.5e-20 72.7 0.0 7.1e-20 71.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG88953.1 - 8.1e-10 38.9 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG88953.1 - 0.00028 21.4 0.0 0.00083 19.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG88953.1 - 0.01 15.4 0.0 0.03 13.8 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG88953.1 - 0.012 15.4 0.2 0.048 13.5 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 GBG88953.1 - 0.014 15.7 0.0 0.058 13.7 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88953.1 - 0.027 15.1 0.0 0.077 13.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.6 GBG88953.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 GBG88954.1 - 7e-05 23.3 0.0 0.00016 22.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88954.1 - 7.5e-05 23.3 0.0 0.00018 22.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG88954.1 - 0.0033 17.7 0.0 0.0086 16.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88954.1 - 0.019 14.8 0.2 0.11 12.2 0.1 2.2 3 0 0 3 3 3 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG88955.1 - 7.3e-24 83.7 0.0 1.3e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88955.1 - 1e-21 77.2 0.0 2e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ACT_3 PF10000.9 GBG88955.1 - 0.098 12.6 0.6 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 ACT domain rve PF00665.26 GBG88956.1 - 4.9e-12 46.1 0.1 1.2e-11 44.9 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DAPDH_C PF16654.5 GBG88956.1 - 0.076 12.9 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain RT_RNaseH_2 PF17919.1 GBG88958.1 - 7.8e-23 80.4 0.0 1.9e-22 79.2 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88958.1 - 4.8e-18 65.5 0.0 6.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG88958.1 - 1.9e-12 47.4 0.0 7e-12 45.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG88958.1 - 0.034 13.3 0.0 0.054 12.6 0.0 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 Retrotrans_gag PF03732.17 GBG88959.1 - 2.8e-05 24.3 1.2 0.074 13.3 0.0 3.7 3 1 1 4 4 4 2 Retrotransposon gag protein MAT1 PF06391.13 GBG88959.1 - 0.75 9.6 3.7 1.1 9.0 3.7 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF659 PF04937.15 GBG88960.1 - 9.5e-28 97.0 0.0 1.5e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Itfg2 PF15907.5 GBG88960.1 - 0.025 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 RVT_1 PF00078.27 GBG88961.1 - 3.6e-05 23.4 0.0 0.00012 21.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG88961.1 - 0.0052 17.0 0.2 0.039 14.2 0.1 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein CDC45 PF02724.14 GBG88961.1 - 8 4.6 10.8 14 3.8 10.8 1.3 1 0 0 1 1 1 0 CDC45-like protein FYVE PF01363.21 GBG88962.1 - 0.099 12.8 1.5 0.18 11.9 1.5 1.3 1 0 0 1 1 1 0 FYVE zinc finger RNA_pol_Rpb2_6 PF00562.28 GBG88963.1 - 2.1e-74 250.9 0.0 2e-45 155.5 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 GBG88963.1 - 3.9e-32 110.5 0.3 1.4e-31 108.7 0.3 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 GBG88963.1 - 1.2e-25 89.5 1.0 3.2e-25 88.2 1.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 GBG88963.1 - 2.6e-22 78.8 0.0 5.7e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 GBG88963.1 - 3.7e-21 75.6 0.5 7.2e-21 74.7 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 GBG88963.1 - 4.3e-12 46.4 0.2 1.4e-11 44.8 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_1 PF04563.15 GBG88963.1 - 0.0024 17.4 0.0 0.0043 16.6 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase beta subunit DUF659 PF04937.15 GBG88964.1 - 1.4e-07 31.4 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CFAP91 PF14738.6 GBG88964.1 - 0.071 13.2 0.2 0.22 11.6 0.2 1.8 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 Nop14 PF04147.12 GBG88964.1 - 0.086 11.0 12.4 0.16 10.1 12.4 1.3 1 0 0 1 1 1 0 Nop14-like family C2 PF00168.30 GBG88965.1 - 7.9e-05 22.9 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain NT-C2 PF10358.9 GBG88966.1 - 1.3e-07 31.5 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins TFIIS_M PF07500.14 GBG88969.1 - 5.7e-32 110.5 1.1 1.4e-31 109.3 1.1 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 GBG88969.1 - 1e-19 70.1 5.6 1.8e-19 69.3 5.6 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 GBG88969.1 - 7.5e-07 29.1 6.5 8.7e-07 28.9 3.7 2.4 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 GBG88969.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.7 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain YtxH PF12732.7 GBG88969.1 - 0.24 11.9 4.5 0.41 11.2 2.8 2.3 1 1 1 2 2 2 0 YtxH-like protein AdoHcyase PF05221.17 GBG88970.1 - 1.6e-145 483.9 0.0 1.8e-145 483.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GBG88970.1 - 3.1e-81 271.2 2.0 4.8e-81 270.6 2.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GBG88970.1 - 1.2e-05 24.8 0.3 2.2e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GBG88970.1 - 0.00019 21.0 0.1 0.00043 19.9 0.1 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 GBG88970.1 - 0.0016 18.7 0.1 0.0037 17.5 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 GBG88970.1 - 0.055 13.4 0.6 0.26 11.1 0.1 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GBG88970.1 - 0.086 13.4 0.2 0.72 10.5 0.1 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 GBG88970.1 - 0.093 12.8 0.2 0.27 11.3 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIY-YIG PF01541.24 GBG88971.1 - 0.0012 19.1 0.1 0.0048 17.1 0.0 2.1 2 0 0 2 2 2 1 GIY-YIG catalytic domain Actin PF00022.19 GBG88972.1 - 1.2e-138 462.2 0.0 4e-138 460.4 0.0 1.7 1 1 0 1 1 1 1 Actin zf-CCHC PF00098.23 GBG88973.1 - 0.00012 21.9 3.5 0.00012 21.9 3.5 1.8 2 0 0 2 2 2 1 Zinc knuckle RVP_2 PF08284.11 GBG88973.1 - 0.0003 20.6 0.0 0.00059 19.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88973.1 - 0.0079 16.7 0.1 0.017 15.6 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Cwf_Cwc_15 PF04889.12 GBG88973.1 - 0.037 13.8 21.5 4.2 7.0 22.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Asp_protease PF09668.10 GBG88973.1 - 0.043 13.6 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG88973.1 - 0.064 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG88973.1 - 0.084 12.7 3.8 0.15 11.9 3.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Nop53 PF07767.11 GBG88973.1 - 0.97 8.8 18.5 1.6 8.0 18.5 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GBG88973.1 - 7.5 4.6 25.4 12 4.0 25.4 1.2 1 0 0 1 1 1 0 Nop14-like family rve PF00665.26 GBG88974.1 - 2.6e-11 43.8 1.3 4.2e-09 36.6 0.1 3.6 3 1 0 3 3 3 1 Integrase core domain RVP_2 PF08284.11 GBG88974.1 - 0.00025 20.8 0.0 0.00059 19.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG88974.1 - 0.00056 20.1 1.5 0.011 16.0 0.1 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG88974.1 - 0.0043 16.9 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG88974.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) MAP7 PF05672.11 GBG88974.1 - 0.18 11.5 11.5 0.36 10.5 11.5 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family RT_RNaseH_2 PF17919.1 GBG88976.1 - 5.1e-32 109.9 0.0 1.1e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88976.1 - 5.3e-30 103.8 0.0 1.3e-29 102.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88976.1 - 9.3e-27 94.0 0.1 1.6e-26 93.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG88976.1 - 1.2e-08 34.9 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG88976.1 - 0.00029 21.4 0.1 0.00084 19.9 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG88976.1 - 0.0027 18.2 0.0 0.016 15.8 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Phage_GPO PF05929.11 GBG88976.1 - 0.0096 15.6 0.3 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 Phage capsid scaffolding protein (GPO) serine peptidase Retrotrans_gag PF03732.17 GBG88976.1 - 0.024 14.9 0.0 0.58 10.5 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG88977.1 - 3.7e-21 75.0 0.0 7.9e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88977.1 - 1e-20 73.9 0.0 7.5e-20 71.2 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88977.1 - 4.7e-13 49.0 0.0 1.6e-12 47.3 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88977.1 - 7.4e-13 48.7 0.0 1.7e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG88977.1 - 1.3e-05 24.8 0.0 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG88977.1 - 0.015 15.1 0.0 0.059 13.2 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_2 PF13696.6 GBG88977.1 - 0.026 14.3 0.4 0.064 13.1 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG88977.1 - 0.035 14.4 0.1 0.2 11.9 0.0 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG88977.1 - 0.21 11.7 0.8 0.68 10.1 0.8 2.0 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG88978.1 - 0.0011 19.4 0.1 0.0054 17.3 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG88978.1 - 0.026 14.3 0.1 0.041 13.7 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG88978.1 - 0.05 13.7 1.9 0.084 13.0 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG88978.1 - 0.12 12.1 0.2 0.25 11.1 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease_2 PF13650.6 GBG88978.1 - 0.14 12.8 0.1 0.72 10.5 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG88979.1 - 1.8e-06 28.2 2.8 2.3e-06 27.9 0.8 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG88979.1 - 0.12 12.7 0.4 0.4 11.0 0.3 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RVT_1 PF00078.27 GBG88981.1 - 1.6e-26 93.2 0.1 2.5e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88981.1 - 4.5e-18 65.1 0.4 4.5e-18 65.1 0.4 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG88981.1 - 1.5e-07 31.6 0.0 6.4e-07 29.6 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG88981.1 - 1.6e-06 28.7 0.0 3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88981.1 - 1.6e-05 24.7 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88981.1 - 4.5e-05 23.9 0.0 9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG88981.1 - 0.022 15.0 0.0 0.087 13.1 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG88981.1 - 0.025 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease ABC_tran PF00005.27 GBG88982.1 - 1.2e-15 58.2 0.0 1.9e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GBG88982.1 - 1.8e-06 27.5 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RVT_1 PF00078.27 GBG88982.1 - 0.0001 21.9 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG88982.1 - 0.0031 17.3 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG88982.1 - 0.0074 16.8 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88982.1 - 0.043 14.5 0.0 0.15 12.7 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease SbcCD_C PF13558.6 GBG88982.1 - 0.053 13.8 0.4 0.55 10.5 0.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 GBG88982.1 - 0.069 11.9 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class RT_RNaseH_2 PF17919.1 GBG88983.1 - 3.8e-28 97.5 0.0 5.8e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88983.1 - 3.6e-26 91.5 0.0 5.5e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88983.1 - 3.2e-17 62.8 0.0 4.9e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YrhK PF14145.6 GBG88983.1 - 0.0091 15.9 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 YrhK-like protein RT_RNaseH_2 PF17919.1 GBG88984.1 - 1.8e-30 104.9 0.0 3.5e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88984.1 - 1.8e-26 92.4 0.0 3.7e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG88984.1 - 2.6e-24 86.0 0.0 4.8e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG88984.1 - 1.3e-16 60.4 0.4 2.8e-16 59.3 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88984.1 - 7.3e-11 42.3 0.0 4.7e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Flagellin_C PF00700.21 GBG88984.1 - 0.1 12.9 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Snapin_Pallidin PF14712.6 GBG88984.1 - 0.17 12.4 1.9 0.29 11.6 0.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Mito_fiss_reg PF05308.11 GBG88984.1 - 0.64 10.1 8.6 1.2 9.2 8.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator gag-asp_proteas PF13975.6 GBG88985.1 - 1.8e-07 31.6 0.0 4.9e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG88985.1 - 2.9e-06 27.8 0.0 8.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG88985.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG88985.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG88985.1 - 0.059 13.6 0.2 0.059 13.6 0.2 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein Vta1 PF04652.16 GBG88985.1 - 0.095 12.7 5.6 0.21 11.5 5.6 1.5 1 0 0 1 1 1 0 Vta1 like NPV_P10 PF05531.12 GBG88985.1 - 5.6 7.5 5.5 2.5e+02 2.2 5.5 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MRP-S35 PF10246.9 GBG88987.1 - 0.052 13.5 0.0 6.6 6.7 0.0 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 C2 PF00168.30 GBG88989.1 - 3.2e-18 65.9 0.0 7.9e-18 64.7 0.0 1.7 1 1 0 1 1 1 1 C2 domain N-glycanase_N PF09112.10 GBG88989.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal RT_RNaseH PF17917.1 GBG88990.1 - 6.9e-28 97.0 0.1 1.6e-27 95.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88990.1 - 1.4e-27 95.6 0.0 4e-27 94.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88990.1 - 2.8e-18 65.7 0.8 6.4e-18 64.6 0.8 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG88990.1 - 6e-15 55.5 0.0 1.9e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG88990.1 - 4e-06 26.5 0.1 0.00025 20.6 0.1 2.4 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG88990.1 - 0.0014 18.8 0.1 0.0042 17.3 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RNA_pol_Rpb2_2 PF04561.14 GBG88990.1 - 0.88 9.2 3.1 7.5 6.1 1.7 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 2 Phage_GPO PF05929.11 GBG88990.1 - 1.5 8.3 5.4 0.5 9.9 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PLD_C PF12357.8 GBG88991.1 - 3.1e-25 87.9 0.0 6.4e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D C terminal PLDc PF00614.22 GBG88991.1 - 3.8e-16 58.5 0.4 4.3e-08 33.0 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GBG88991.1 - 5.9e-09 35.9 0.3 1.4e-06 28.3 0.0 2.7 3 0 0 3 3 3 2 PLD-like domain Phage_lysozyme PF00959.19 GBG88992.1 - 0.058 13.9 0.1 0.16 12.5 0.0 1.7 2 0 0 2 2 2 0 Phage lysozyme HTH_Tnp_IS630 PF01710.16 GBG88993.1 - 0.0074 16.3 0.0 0.008 16.2 0.0 1.1 1 0 0 1 1 1 1 Transposase Gram_pos_anchor PF00746.21 GBG88993.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Pec_lyase_C PF00544.19 GBG88994.1 - 1.7e-34 119.2 0.1 4.6e-34 117.9 0.1 1.6 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG88994.1 - 0.00054 19.8 0.9 0.0024 17.7 0.8 2.1 1 1 1 2 2 2 1 Right handed beta helix region RT_RNaseH PF17917.1 GBG88995.1 - 2e-23 82.7 0.0 3.7e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG88995.1 - 1.3e-22 79.7 0.0 2.6e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG88995.1 - 3.3e-17 62.3 0.3 7.3e-17 61.2 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG88995.1 - 0.00012 21.6 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG88995.1 - 0.055 13.7 0.3 0.12 12.7 0.1 1.6 2 0 0 2 2 2 0 H2C2 zinc finger Regulator_TrmB PF11495.8 GBG88995.1 - 0.089 12.0 0.0 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Pec_lyase_C PF00544.19 GBG88996.1 - 5.3e-32 111.1 0.0 1e-31 110.2 0.0 1.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GBG88996.1 - 0.0027 17.6 0.8 0.013 15.3 0.9 2.2 1 1 1 2 2 2 1 Right handed beta helix region DUF5427 PF10310.9 GBG88997.1 - 0.034 13.1 12.7 0.039 12.9 12.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PA26 PF04636.13 GBG88997.1 - 0.053 12.4 10.6 0.064 12.2 10.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Herpes_UL25 PF01499.16 GBG88997.1 - 0.33 9.4 8.1 0.4 9.2 8.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3138 PF11336.8 GBG88997.1 - 0.45 9.1 1.6 0.52 8.9 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PRTP PF01366.18 GBG88997.1 - 0.51 8.3 6.2 0.51 8.3 6.2 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein HAUS6_N PF14661.6 GBG88997.1 - 1.1 8.7 13.5 1.6 8.2 13.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TP53IP5 PF15331.6 GBG88997.1 - 1.4 9.0 11.3 1.5 8.9 11.3 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 FAM60A PF15396.6 GBG88997.1 - 2.8 7.9 9.0 3.1 7.8 9.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF755 PF05501.11 GBG88997.1 - 2.9 8.2 13.2 4.2 7.7 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DDHD PF02862.17 GBG88997.1 - 4 7.5 7.3 4.1 7.5 7.3 1.1 1 0 0 1 1 1 0 DDHD domain TMPIT PF07851.13 GBG88997.1 - 5 6.3 8.5 5.9 6.0 8.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein ALMT PF11744.8 GBG88997.1 - 5.8 5.6 8.7 6.1 5.6 8.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 GBG88997.1 - 7.5 5.3 6.7 8.7 5.1 6.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PIEZO PF15917.5 GBG88997.1 - 8.7 5.7 14.6 9.9 5.6 14.6 1.2 1 0 0 1 1 1 0 Piezo RVT_1 PF00078.27 GBG88998.1 - 5.6e-32 111.1 0.1 8.3e-32 110.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG88998.1 - 4.8e-26 90.7 0.0 1.2e-25 89.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG88998.1 - 1.2e-24 86.6 0.0 3.3e-24 85.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG88998.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DDE_Tnp_4 PF13359.6 GBG88999.1 - 2.4e-11 43.5 0.1 6.6e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG88999.1 - 3e-09 36.8 0.0 5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein SDA1 PF05285.12 GBG89000.1 - 0.12 11.8 23.4 0.15 11.4 23.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG89000.1 - 0.15 11.4 21.2 0.19 11.0 21.2 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GBG89000.1 - 0.17 10.7 7.7 0.21 10.3 7.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG89000.1 - 0.3 9.2 21.7 0.38 8.9 21.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG89000.1 - 0.33 9.2 16.2 0.43 8.8 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG89000.1 - 1.4 8.6 17.6 2.1 8.0 17.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_S64 PF08192.11 GBG89000.1 - 1.6 7.2 4.3 2 6.8 4.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.7 GBG89000.1 - 2.3 6.2 7.1 3.2 5.8 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 GBG89000.1 - 3.8 6.2 10.9 4.9 5.8 10.9 1.2 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 GBG89000.1 - 5.6 5.9 10.2 7.1 5.6 10.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF659 PF04937.15 GBG89003.1 - 5.2e-33 114.1 0.2 7.4e-33 113.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GNAT_acetyltr_2 PF13718.6 GBG89005.1 - 0.35 10.2 1.1 0.81 9.0 1.1 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DEC-1_N PF04625.13 GBG89005.1 - 2.7 6.9 5.0 4.4 6.2 5.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Retrotrans_gag PF03732.17 GBG89006.1 - 0.0017 18.6 3.9 0.0057 16.9 0.6 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein TFIIA PF03153.13 GBG89006.1 - 0.14 12.1 9.5 0.2 11.6 9.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 GBG89006.1 - 0.81 9.0 22.5 4.2 6.6 21.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DNA_pol_B_palm PF14792.6 GBG89007.1 - 3.1e-28 98.2 0.0 5.6e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 GBG89007.1 - 5.2e-22 77.8 0.9 1e-21 76.9 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 GBG89007.1 - 1e-17 63.7 0.0 2.2e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 GBG89007.1 - 1.5e-14 54.0 0.1 1e-13 51.4 0.0 2.4 2 1 1 3 3 3 1 Helix-hairpin-helix domain HHH_5 PF14520.6 GBG89007.1 - 4.5e-07 30.4 0.0 4e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 GBG89007.1 - 0.0028 18.0 0.0 0.0056 17.1 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Cdd1 PF11731.8 GBG89007.1 - 0.01 16.1 0.0 0.033 14.4 0.0 2.0 1 0 0 1 1 1 0 Pathogenicity locus NTP_transf_2 PF01909.23 GBG89007.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Chromo PF00385.24 GBG89008.1 - 1e-12 47.7 0.0 2.1e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG89008.1 - 9e-09 35.5 0.2 2.7e-08 34.0 0.2 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG89008.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Glyco_transf_24 PF18404.1 GBG89010.1 - 2.9e-144 479.4 2.5 5.2e-144 478.6 2.5 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 GBG89010.1 - 9.7e-52 176.4 0.0 6.4e-49 167.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 GBG89010.1 - 6.7e-35 120.7 0.0 1.3e-34 119.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 GBG89010.1 - 6.5e-34 117.7 0.3 2.3e-33 116.0 0.3 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 GBG89010.1 - 1.5e-33 115.1 0.0 3.5e-33 114.0 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 GBG89010.1 - 3.7e-26 91.6 5.7 6.6e-26 90.9 3.8 2.4 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 GBG89010.1 - 1.6e-06 27.9 0.1 3.1e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 AbiJ_NTD5 PF18865.1 GBG89010.1 - 0.062 13.1 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 RT_RNaseH_2 PF17919.1 GBG89013.1 - 2.5e-34 117.3 0.0 4.9e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89013.1 - 3.2e-32 110.9 0.0 6.9e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glyco_transf_64 PF09258.10 GBG89014.1 - 1.9e-63 214.0 0.0 3.7e-63 213.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 GBG89014.1 - 0.00011 21.9 6.4 0.0029 17.2 2.6 3.4 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GBG89014.1 - 0.0038 16.6 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative CdiI_N PF18228.1 GBG89014.1 - 0.12 12.2 0.0 21 5.0 0.0 2.7 2 0 0 2 2 2 0 CdiI N-terminal domain DUF3446 PF11928.8 GBG89014.1 - 1.9 8.8 11.9 0.31 11.4 3.4 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 GBG89014.1 - 5 6.7 9.6 9.2 5.8 9.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 GBG89015.1 - 1.9e-34 119.3 0.0 2.5e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG89015.1 - 5.9e-17 61.8 0.0 2.3e-07 30.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 GBG89015.1 - 0.00022 20.7 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RT_RNaseH_2 PF17919.1 GBG89016.1 - 1.7e-18 66.5 0.0 3.2e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89016.1 - 1.4e-15 57.4 0.0 2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89016.1 - 2.2e-07 31.1 0.0 4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDHD PF02862.17 GBG89016.1 - 1.5 9.0 4.3 2.9 8.0 4.3 1.5 1 0 0 1 1 1 0 DDHD domain BUD22 PF09073.10 GBG89016.1 - 2.4 7.4 35.5 3.4 6.9 35.5 1.1 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.7 GBG89016.1 - 7 4.6 16.5 13 3.8 16.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleotid_trans PF03407.16 GBG89017.1 - 7.7e-09 35.8 0.0 3.5e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase SPX PF03105.19 GBG89017.1 - 0.012 15.5 6.4 0.016 15.2 6.4 1.3 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 GBG89017.1 - 0.073 11.9 4.0 0.079 11.8 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Roughex PF06020.11 GBG89017.1 - 0.31 10.1 20.9 0.46 9.5 20.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein LAP1C PF05609.12 GBG89017.1 - 0.6 9.1 9.4 0.75 8.8 9.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 GBG89017.1 - 1.2 7.6 7.0 1.5 7.3 7.0 1.1 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 GBG89017.1 - 2.9 7.2 20.3 3.9 6.7 20.3 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 GBG89017.1 - 4 6.7 16.7 5.8 6.2 16.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 GBG89017.1 - 4.4 6.0 10.8 6.2 5.5 10.8 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG89017.1 - 4.5 5.4 23.1 5.9 5.0 23.1 1.0 1 0 0 1 1 1 0 Nop14-like family TERB2 PF15101.6 GBG89017.1 - 4.6 7.2 8.8 7.6 6.5 8.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NOB1_Zn_bind PF08772.11 GBG89018.1 - 0.092 12.9 0.3 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Pkinase PF00069.25 GBG89019.1 - 1.2e-12 47.8 0.0 2.2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG89019.1 - 0.038 13.9 0.2 0.17 11.8 0.2 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Fasciclin PF02469.22 GBG89021.1 - 4.8e-14 52.7 0.0 5.7e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain DUF1290 PF06947.12 GBG89021.1 - 0.038 14.1 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) Beta_elim_lyase PF01212.21 GBG89021.1 - 0.097 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Fasciclin PF02469.22 GBG89022.1 - 1.7e-13 50.9 0.0 2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain RCDG1 PF15725.5 GBG89022.1 - 0.034 14.6 0.7 0.034 14.6 0.7 1.9 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Beta_elim_lyase PF01212.21 GBG89022.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Fasciclin PF02469.22 GBG89023.1 - 1e-13 51.6 0.0 1.3e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Beta_elim_lyase PF01212.21 GBG89023.1 - 0.075 12.3 0.1 0.09 12.0 0.1 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase PRIMA1 PF16101.5 GBG89023.1 - 0.078 13.0 3.7 0.13 12.3 3.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1290 PF06947.12 GBG89023.1 - 0.1 12.7 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) CAP_N PF01213.19 GBG89023.1 - 1.4 8.3 7.5 2.1 7.8 7.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ral PF11058.8 GBG89024.1 - 0.081 12.5 0.1 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Antirestriction protein Ral RT_RNaseH_2 PF17919.1 GBG89025.1 - 8.6e-41 138.0 0.5 1.2e-26 92.7 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89025.1 - 1.1e-36 125.3 0.7 5.7e-20 71.6 0.3 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89025.1 - 5e-26 91.6 0.1 3.1e-25 89.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG89025.1 - 1.1e-20 73.5 0.1 2.4e-20 72.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89025.1 - 2.8e-14 53.3 0.0 8.5e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG89025.1 - 0.00022 21.7 0.0 0.00095 19.7 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG89025.1 - 0.00023 21.3 0.0 0.00096 19.3 0.0 2.2 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG89025.1 - 0.00041 20.9 0.0 0.0011 19.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG89025.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF2862 PF11061.8 GBG89025.1 - 0.048 13.5 0.4 0.29 11.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) DNA_gyraseA_C PF03989.13 GBG89025.1 - 0.048 13.1 0.1 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Asp_protease PF09668.10 GBG89025.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease HTH_36 PF13730.6 GBG89025.1 - 0.19 11.7 0.5 16 5.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 GBG89025.1 - 1 9.0 3.2 30 4.3 0.3 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding RVT_1 PF00078.27 GBG89026.1 - 3.6e-25 88.8 0.4 7e-25 87.8 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89026.1 - 3.7e-24 85.0 0.0 6.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89026.1 - 8.2e-24 83.5 0.0 1.5e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89026.1 - 5.1e-16 58.5 0.0 1.1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG89026.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG89027.1 - 2.3e-24 85.3 0.0 1.6e-23 82.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89027.1 - 4e-24 84.9 0.0 9.4e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89027.1 - 7.4e-21 74.0 0.1 1.5e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89027.1 - 1.2e-09 38.4 0.0 3.7e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89027.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger SlyX PF04102.12 GBG89027.1 - 1.5 9.5 10.4 5.4 7.7 0.1 3.6 3 0 0 3 3 3 0 SlyX zf-CCHC_3 PF13917.6 GBG89028.1 - 0.00049 20.0 1.5 0.001 19.0 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GBG89028.1 - 1.4 9.1 3.7 2.4 8.4 3.7 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG89029.1 - 4.4e-34 116.5 0.0 9.2e-34 115.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89029.1 - 1e-30 106.1 0.0 2.4e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89029.1 - 1.2e-16 60.6 0.1 2.6e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89029.1 - 3e-15 56.5 0.0 1.3e-14 54.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG89030.1 - 9.1e-17 60.9 0.1 1.9e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89030.1 - 2.8e-15 56.6 0.0 8.8e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Trypsin PF00089.26 GBG89031.1 - 2.4e-52 177.9 0.7 1.5e-45 155.7 0.2 2.5 2 0 0 2 2 2 2 Trypsin RVT_1 PF00078.27 GBG89032.1 - 3.1e-29 102.1 0.1 2.8e-21 76.0 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89032.1 - 0.0015 18.7 0.0 0.0039 17.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG89032.1 - 0.0076 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG89032.1 - 0.05 13.9 2.1 0.098 12.9 0.0 2.5 3 0 0 3 3 3 0 Retrotransposon gag protein DUF452 PF04301.13 GBG89032.1 - 0.11 12.0 0.0 15 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF452) DUF659 PF04937.15 GBG89034.1 - 1.8e-15 57.1 0.0 1.3e-14 54.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) B3 PF02362.21 GBG89034.1 - 5.8e-05 22.9 0.1 0.00014 21.6 0.1 1.6 1 0 0 1 1 1 1 B3 DNA binding domain RT_RNaseH_2 PF17919.1 GBG89035.1 - 1.1e-33 115.2 0.1 2.7e-33 114.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89035.1 - 1.3e-29 102.6 0.1 2.9e-29 101.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89035.1 - 2.3e-12 46.9 0.1 6.3e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Apc13p PF05839.11 GBG89035.1 - 0.024 14.8 0.5 0.15 12.3 0.5 2.3 2 0 0 2 2 2 0 Apc13p protein DUF5095 PF17016.5 GBG89035.1 - 0.13 11.9 0.1 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) RT_RNaseH_2 PF17919.1 GBG89036.1 - 8.4e-14 51.4 0.0 2.4e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89036.1 - 2.5e-12 46.8 0.1 4.9e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) B3 PF02362.21 GBG89036.1 - 8.6e-07 28.8 3.7 2.5e-06 27.3 0.0 3.4 4 0 0 4 4 4 1 B3 DNA binding domain RT_RNaseH PF17917.1 GBG89036.1 - 0.00044 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PCEMA1 PF07418.11 GBG89036.1 - 0.3 10.6 12.3 0.6 9.6 12.3 1.4 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 RVT_1 PF00078.27 GBG89037.1 - 2.8e-20 72.8 0.0 7.2e-20 71.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PriCT_1 PF08708.11 GBG89037.1 - 0.047 13.4 0.1 2.7 7.8 0.0 2.8 3 0 0 3 3 3 0 Primase C terminal 1 (PriCT-1) Chromo PF00385.24 GBG89038.1 - 0.0023 17.8 0.0 0.0023 17.8 0.0 2.2 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Adaptin_binding PF10199.9 GBG89038.1 - 0.039 14.5 1.3 0.18 12.4 1.3 2.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Gp58 PF07902.11 GBG89038.1 - 0.88 7.8 4.1 1.3 7.2 4.1 1.2 1 0 0 1 1 1 0 gp58-like protein FUSC PF04632.12 GBG89038.1 - 2.1 6.8 15.4 5.7 5.3 15.4 1.8 1 0 0 1 1 1 0 Fusaric acid resistance protein family CLZ PF16526.5 GBG89038.1 - 2.5 8.5 7.1 9.7 6.6 4.9 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fzo_mitofusin PF04799.13 GBG89038.1 - 2.6 7.6 6.7 13 5.3 3.4 2.5 2 0 0 2 2 2 0 fzo-like conserved region Snapin_Pallidin PF14712.6 GBG89038.1 - 4.4 7.8 11.4 1.7 9.1 3.9 3.2 3 0 0 3 3 3 0 Snapin/Pallidin Laminin_II PF06009.12 GBG89038.1 - 8.7 6.4 11.1 2 8.4 0.4 3.6 3 1 1 4 4 4 0 Laminin Domain II LMBR1 PF04791.16 GBG89039.1 - 0.25 10.2 16.5 0.31 9.9 15.9 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF659 PF04937.15 GBG89040.1 - 1.3e-23 83.6 0.0 6e-12 45.7 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG89041.1 - 1.3e-65 217.7 0.1 1.2e-31 108.7 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89041.1 - 5.6e-62 206.6 0.9 1.2e-30 105.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89041.1 - 9.5e-10 38.4 3.3 2.2e-08 34.1 2.0 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG89041.1 - 0.00068 19.2 0.1 0.37 10.3 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89041.1 - 0.0086 16.3 0.0 0.036 14.2 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain PaaX_C PF08223.11 GBG89041.1 - 0.046 14.0 2.3 0.5 10.7 0.1 3.3 3 0 0 3 3 3 0 PaaX-like protein C-terminal domain Phage_GPO PF05929.11 GBG89041.1 - 0.13 11.9 0.1 0.13 11.9 0.1 3.2 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase TMEM154 PF15102.6 GBG89042.1 - 0.061 13.2 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF4448 PF14610.6 GBG89042.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CD34_antigen PF06365.12 GBG89042.1 - 0.11 12.0 0.1 0.27 10.8 0.1 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family Paf1 PF03985.13 GBG89043.1 - 1.8e-11 43.7 3.7 1.8e-11 43.7 3.7 3.5 1 1 2 3 3 3 1 Paf1 HNH_3 PF13392.6 GBG89043.1 - 0.0032 17.2 0.1 0.0062 16.3 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease TRAM_LAG1_CLN8 PF03798.16 GBG89044.1 - 3.2e-40 138.0 26.8 5.7e-40 137.2 26.8 1.4 1 0 0 1 1 1 1 TLC domain PQQ_3 PF13570.6 GBG89044.1 - 3.7e-07 30.4 6.9 0.19 12.3 0.6 5.4 4 1 1 5 5 5 3 PQQ-like domain PQQ_2 PF13360.6 GBG89044.1 - 4.2e-07 29.8 0.1 0.016 14.8 0.0 2.3 1 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 GBG89044.1 - 1.7e-06 27.7 5.5 0.0023 17.8 0.1 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat Exo_endo_phos PF03372.23 GBG89045.1 - 2e-11 43.9 0.0 3.1e-11 43.2 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG89045.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF659 PF04937.15 GBG89046.1 - 3.4e-29 101.7 0.1 6.8e-29 100.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SseC PF04888.12 GBG89046.1 - 0.003 17.2 9.7 0.005 16.5 9.7 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ARGLU PF15346.6 GBG89046.1 - 1.6 8.6 13.6 3.1 7.7 13.6 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 gag-asp_proteas PF13975.6 GBG89047.1 - 8.6e-07 29.4 0.2 2.5e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89047.1 - 2.7e-05 24.7 0.1 8.1e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG89047.1 - 0.00028 20.7 0.1 0.00045 20.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG89047.1 - 0.022 14.4 0.2 0.043 13.5 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVP_2 PF08284.11 GBG89047.1 - 0.044 13.5 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89048.1 - 0.0037 17.9 0.0 0.011 16.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89048.1 - 0.0039 17.7 0.1 0.0094 16.5 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG89048.1 - 0.091 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Myosin_head PF00063.21 GBG89049.1 - 4.4e-213 709.3 4.7 5.4e-213 709.0 4.7 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 GBG89049.1 - 2.7e-06 27.1 2.0 5.3e-06 26.2 2.0 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.6 GBG89049.1 - 0.0025 18.1 1.0 0.064 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG89049.1 - 0.017 15.5 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 GBG89049.1 - 0.029 13.9 0.2 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain TsaE PF02367.17 GBG89049.1 - 0.036 14.1 0.1 0.087 12.8 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 GBG89049.1 - 0.053 12.5 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Radial_spoke_3 PF06098.11 GBG89049.1 - 0.069 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 AAA_22 PF13401.6 GBG89049.1 - 0.079 13.2 0.1 0.34 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GBG89049.1 - 0.083 12.2 0.2 0.17 11.1 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin Adenyl_cycl_N PF12633.7 GBG89049.1 - 0.13 12.2 0.8 21 4.9 0.2 3.1 2 1 0 2 2 2 0 Adenylate cyclase NT domain BBP1_C PF15272.6 GBG89050.1 - 0.0099 15.7 2.8 0.0099 15.7 2.8 2.4 3 0 0 3 3 3 1 Spindle pole body component BBP1, C-terminal DUF4706 PF15797.5 GBG89050.1 - 0.037 14.6 1.2 0.28 11.8 1.2 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4706) zf-CCHC_5 PF14787.6 GBG89050.1 - 0.11 12.3 2.5 0.2 11.4 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GBG89050.1 - 0.66 10.2 3.9 1.3 9.2 3.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG89052.1 - 4.6e-19 68.6 0.0 1.4e-18 67.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89052.1 - 7.8e-08 32.2 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89052.1 - 7.6e-06 25.7 0.0 0.0031 17.2 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG89054.1 - 8e-10 39.0 2.6 1.5e-09 38.1 1.3 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG89054.1 - 0.076 13.1 0.9 0.18 11.9 0.9 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG89054.1 - 0.093 13.1 3.6 0.11 12.8 0.9 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HEAT_EZ PF13513.6 GBG89054.1 - 0.11 13.1 0.6 0.35 11.4 0.0 2.2 2 0 0 2 2 2 0 HEAT-like repeat RT_RNaseH_2 PF17919.1 GBG89055.1 - 5.4e-28 97.0 0.1 5.8e-25 87.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89055.1 - 1.4e-25 89.6 0.1 1.8e-24 86.0 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89055.1 - 9.4e-20 70.5 0.1 2e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG89055.1 - 1.1e-07 31.7 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89055.1 - 1.2e-06 29.1 0.0 3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG89055.1 - 1.3e-06 28.1 2.2 6.4e-06 25.8 0.0 2.7 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG89055.1 - 0.00012 22.6 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG89055.1 - 0.024 14.8 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG89055.1 - 0.034 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF2730 PF10805.8 GBG89055.1 - 0.091 12.9 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) APG17 PF04108.12 GBG89055.1 - 0.1 11.7 0.2 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 Autophagy protein Apg17 SlyX PF04102.12 GBG89055.1 - 2.6 8.7 7.8 0.71 10.5 0.3 3.5 2 1 1 3 3 3 0 SlyX TMF_TATA_bd PF12325.8 GBG89055.1 - 7.2 6.9 5.1 1.1 9.4 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0492 PF15744.5 GBG89056.1 - 0.47 9.6 2.7 0.79 8.9 2.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 DUF347 PF03988.12 GBG89058.1 - 0.07 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) CDC45 PF02724.14 GBG89058.1 - 0.13 10.5 6.5 0.17 10.2 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 GBG89058.1 - 0.95 8.4 14.7 1.3 7.9 14.7 1.2 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 GBG89058.1 - 1.2 7.2 8.5 1.8 6.6 8.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi SRP54_N PF02881.19 GBG89059.1 - 0.052 13.8 0.2 0.1 12.8 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain RVT_1 PF00078.27 GBG89059.1 - 0.074 12.6 0.0 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89060.1 - 5.3e-54 180.4 0.0 2.7e-26 91.5 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89060.1 - 3e-49 165.7 0.0 1.3e-23 83.2 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Lon_C PF05362.13 GBG89060.1 - 6.7e-49 166.2 0.5 1.5e-36 125.8 0.0 3.0 2 1 1 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain RVT_1 PF00078.27 GBG89060.1 - 4.8e-32 111.3 0.2 5.4e-26 91.5 0.0 3.4 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) AAA PF00004.29 GBG89060.1 - 6.1e-21 75.2 0.0 2.7e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Integrase_H2C2 PF17921.1 GBG89060.1 - 8.9e-17 60.9 0.1 3.1e-16 59.2 0.1 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain AAA_5 PF07728.14 GBG89060.1 - 5.6e-09 36.1 0.0 3.5e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Retrotrans_gag PF03732.17 GBG89060.1 - 1.3e-07 31.8 0.6 0.026 14.8 0.0 4.0 3 0 0 3 3 3 2 Retrotransposon gag protein rve PF00665.26 GBG89060.1 - 1.2e-05 25.4 0.0 4.7e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain AAA_3 PF07726.11 GBG89060.1 - 0.00016 21.5 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GBG89060.1 - 0.0075 16.0 0.0 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GBG89060.1 - 0.0091 16.2 4.3 0.046 13.9 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG89060.1 - 0.013 15.9 0.0 0.013 15.9 0.0 4.8 6 0 0 6 6 6 0 AAA ATPase domain Integrin_b_cyt PF08725.11 GBG89060.1 - 0.061 13.0 0.0 4.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain RNA_helicase PF00910.22 GBG89060.1 - 0.12 12.7 0.0 0.42 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 GBG89060.1 - 0.25 10.9 2.1 0.47 10.0 0.0 2.7 3 0 0 3 3 1 0 AAA domain FeoC PF09012.10 GBG89060.1 - 0.6 10.2 0.0 0.6 10.2 0.0 2.6 2 0 0 2 2 2 0 FeoC like transcriptional regulator AAA_23 PF13476.6 GBG89060.1 - 4.1 7.9 0.0 4.1 7.9 0.0 4.1 3 3 0 3 3 1 0 AAA domain Lon_C PF05362.13 GBG89061.1 - 6.5e-78 261.0 0.6 2.4e-77 259.1 0.3 2.0 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain RT_RNaseH_2 PF17919.1 GBG89061.1 - 5.5e-54 180.4 0.0 2.7e-26 91.5 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89061.1 - 3.1e-49 165.6 0.0 1.4e-23 83.2 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89061.1 - 5e-32 111.2 0.2 5.5e-26 91.5 0.0 3.4 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) AAA PF00004.29 GBG89061.1 - 6.4e-21 75.2 0.0 2.8e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Integrase_H2C2 PF17921.1 GBG89061.1 - 9.2e-17 60.9 0.1 3.2e-16 59.2 0.1 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain AAA_5 PF07728.14 GBG89061.1 - 5.8e-09 36.1 0.0 3.6e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Retrotrans_gag PF03732.17 GBG89061.1 - 1.4e-07 31.7 0.6 0.026 14.8 0.0 3.9 3 0 0 3 3 3 2 Retrotransposon gag protein rve PF00665.26 GBG89061.1 - 1.3e-05 25.4 0.0 4.8e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain ChlI PF13541.6 GBG89061.1 - 3.7e-05 23.6 0.0 0.00011 22.0 0.0 1.9 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_3 PF07726.11 GBG89061.1 - 0.00016 21.5 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GBG89061.1 - 0.0077 16.0 0.0 0.043 13.6 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GBG89061.1 - 0.0094 16.1 4.3 0.046 13.9 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG89061.1 - 0.013 15.9 0.0 0.013 15.9 0.0 4.8 6 0 0 6 6 6 0 AAA ATPase domain Integrin_b_cyt PF08725.11 GBG89061.1 - 0.063 13.0 0.0 4.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain RNA_helicase PF00910.22 GBG89061.1 - 0.13 12.7 0.0 0.42 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 GBG89061.1 - 0.22 11.1 1.9 0.47 10.0 0.0 2.6 3 0 0 3 3 1 0 AAA domain FeoC PF09012.10 GBG89061.1 - 0.61 10.2 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 1 0 FeoC like transcriptional regulator AAA_23 PF13476.6 GBG89061.1 - 3.9 7.9 0.0 3.9 7.9 0.0 4.1 3 3 0 3 3 1 0 AAA domain DUF5119 PF17145.4 GBG89062.1 - 0.21 11.5 1.3 0.52 10.2 0.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5119) DUF659 PF04937.15 GBG89063.1 - 1.9e-33 115.5 0.1 2.9e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89063.1 - 3.8e-07 29.8 0.1 1e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PadR PF03551.14 GBG89063.1 - 0.038 14.0 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family CDC45 PF02724.14 GBG89064.1 - 0.32 9.2 20.2 0.44 8.8 20.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG89064.1 - 0.71 8.0 26.9 0.89 7.7 26.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG89064.1 - 1.3 8.4 27.1 1.7 8.0 27.1 1.1 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 GBG89064.1 - 2.3 7.5 25.5 2.9 7.2 25.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2151 PF10221.9 GBG89064.1 - 3 6.3 6.8 3.5 6.1 6.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Presenilin PF01080.17 GBG89064.1 - 8.2 5.1 11.7 11 4.7 11.7 1.3 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GBG89064.1 - 9.2 5.4 7.6 12 5.0 7.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SKA1 PF07160.12 GBG89065.1 - 3.4e-38 131.8 0.5 4.8e-38 131.4 0.5 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 SKA1 PF07160.12 GBG89066.1 - 3.8e-39 135.0 0.4 5.3e-39 134.5 0.4 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 CCDC106 PF15794.5 GBG89066.1 - 0.18 11.5 4.6 1.8 8.2 0.1 2.6 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 106 Sec39 PF08314.11 GBG89067.1 - 7.4e-29 100.8 0.0 3.5e-15 55.6 0.0 2.1 2 0 0 2 2 2 2 Secretory pathway protein Sec39 CDC45 PF02724.14 GBG89067.1 - 0.02 13.2 2.9 0.042 12.2 2.9 1.4 1 0 0 1 1 1 0 CDC45-like protein RNA12 PF10443.9 GBG89067.1 - 0.17 10.6 0.5 0.28 9.9 0.5 1.2 1 0 0 1 1 1 0 RNA12 protein SURF2 PF05477.11 GBG89067.1 - 0.33 10.6 2.8 0.78 9.4 2.8 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2457 PF10446.9 GBG89067.1 - 7.3 5.6 10.1 16 4.5 10.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IF4E PF01652.18 GBG89068.1 - 7e-52 175.4 0.3 8.5e-52 175.2 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E E1_dh PF00676.20 GBG89069.1 - 9.2e-09 34.7 0.5 1.1e-08 34.4 0.5 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Peptidase_M50 PF02163.22 GBG89071.1 - 0.00077 18.8 4.5 0.00094 18.5 1.8 2.2 1 1 1 2 2 2 1 Peptidase family M50 DUF4607 PF15380.6 GBG89071.1 - 0.13 11.7 1.7 0.22 11.0 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) Ribosomal_L32e PF01655.18 GBG89073.1 - 1.4e-50 170.2 0.7 1.7e-50 170.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 RVT_1 PF00078.27 GBG89074.1 - 2.1e-25 89.6 0.0 3.5e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89074.1 - 2.1e-17 63.0 0.0 9.4e-17 60.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89074.1 - 4.4e-17 61.9 0.2 1.4e-16 60.4 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG89074.1 - 2.3e-11 43.9 0.0 2.2e-08 34.3 0.0 3.0 2 1 1 3 3 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG89074.1 - 1.3e-08 35.1 0.0 4.1e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG89074.1 - 4.8e-07 30.3 0.0 1.1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89074.1 - 5.5e-07 30.1 0.0 1.3e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ABC_tran PF00005.27 GBG89074.1 - 6.4e-07 30.0 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RVP_2 PF08284.11 GBG89074.1 - 6e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89074.1 - 0.00023 21.0 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease ABC2_membrane PF01061.24 GBG89074.1 - 0.0012 18.3 0.4 0.0012 18.3 0.4 2.1 2 0 0 2 2 2 1 ABC-2 type transporter AAA_29 PF13555.6 GBG89074.1 - 0.0013 18.4 0.1 0.0034 17.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 GBG89074.1 - 0.0023 17.5 0.0 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 GBG89074.1 - 0.0059 16.5 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 GBG89074.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain AAA_16 PF13191.6 GBG89074.1 - 0.027 14.9 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 GBG89074.1 - 0.033 14.7 0.0 0.074 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GBG89074.1 - 0.062 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG89074.1 - 0.072 13.0 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 1 0 NACHT domain RsgA_GTPase PF03193.16 GBG89074.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 GBG89074.1 - 0.17 11.3 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 GBG89074.1 - 0.19 12.3 0.2 0.55 10.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain RVT_1 PF00078.27 GBG89075.1 - 6.4e-12 45.5 0.0 9.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NRN1 PF15056.6 GBG89075.1 - 0.25 11.5 1.0 3.9 7.6 1.0 2.2 2 0 0 2 2 2 0 Neuritin protein family RT_RNaseH PF17917.1 GBG89076.1 - 8.2e-22 77.5 0.0 2e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89076.1 - 2.1e-21 75.8 0.0 5.9e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89076.1 - 2.9e-18 65.7 0.4 6e-18 64.7 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG89076.1 - 2.6e-15 56.6 0.6 1.9e-11 43.9 0.0 3.1 3 1 1 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG89076.1 - 4.2e-07 29.8 0.0 8.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89076.1 - 8.9e-05 23.1 0.0 0.0003 21.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89076.1 - 9.7e-05 22.9 0.0 0.00043 20.8 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF4187 PF13821.6 GBG89076.1 - 0.71 9.7 4.7 0.34 10.7 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Ketoacyl-synt_2 PF13723.6 GBG89079.1 - 0.11 12.1 0.5 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DUF659 PF04937.15 GBG89080.1 - 1.9e-32 112.2 0.4 3.6e-32 111.3 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG89080.1 - 1.9e-31 108.0 0.2 3.5e-31 107.2 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89080.1 - 6e-27 94.0 0.1 1.6e-26 92.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89080.1 - 1.7e-19 69.7 1.9 2.7e-17 62.6 0.1 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG89080.1 - 0.077 13.2 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG89081.1 - 2.5e-25 88.4 0.0 5.7e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89081.1 - 1.1e-20 73.8 0.0 2.8e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89081.1 - 7.9e-15 55.0 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG89081.1 - 0.0092 15.9 0.3 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG89082.1 - 0.00012 22.6 0.0 0.00031 21.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89082.1 - 0.0002 21.9 0.0 0.00053 20.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG89082.1 - 0.00057 19.7 0.0 0.0014 18.4 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG89082.1 - 0.00076 19.7 4.8 0.072 13.4 0.1 3.4 3 0 0 3 3 3 2 Retrotransposon gag protein PIEZO PF15917.5 GBG89082.1 - 2.3 7.6 14.4 0.16 11.5 7.8 2.3 3 0 0 3 3 3 0 Piezo CLZ PF16526.5 GBG89082.1 - 7.1 7.1 9.1 0.38 11.1 1.3 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CorA PF01544.18 GBG89083.1 - 9.9e-08 31.6 5.0 2.7e-07 30.2 0.7 2.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Chromo PF00385.24 GBG89083.1 - 0.027 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ATP_synt_H PF05493.13 GBG89083.1 - 0.038 14.5 1.8 0.086 13.3 1.8 1.6 1 0 0 1 1 1 0 ATP synthase subunit H Prok-TraM PF09228.10 GBG89083.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Baculo_PEP_C PF04513.12 GBG89083.1 - 0.44 10.6 4.2 0.79 9.8 0.7 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2390 PF09523.10 GBG89083.1 - 0.92 9.9 4.0 3 8.2 0.4 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2390) HalX PF08663.10 GBG89083.1 - 5.3 7.4 7.3 1.2 9.5 2.6 2.3 2 1 0 2 2 2 0 HalX domain LRR_6 PF13516.6 GBG89085.1 - 9.4e-22 75.2 11.0 0.032 14.3 0.0 10.6 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.7 GBG89085.1 - 2e-11 43.9 0.6 0.0079 16.6 0.0 6.6 7 1 1 8 8 8 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 GBG89085.1 - 4.5e-11 42.5 0.7 4.5e-11 42.5 0.7 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 GBG89085.1 - 3.1e-09 36.5 1.5 9.3e-09 35.0 0.5 2.4 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 GBG89085.1 - 3.9e-05 23.6 4.2 78 4.4 0.0 7.6 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 GBG89085.1 - 0.0048 16.6 1.1 14 5.5 0.0 4.9 4 1 1 5 5 5 2 Leucine rich repeat LRR_6 PF13516.6 GBG89086.1 - 2.8e-14 51.9 23.1 0.00012 21.8 0.5 7.4 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 GBG89086.1 - 0.0014 19.0 19.4 1.3 9.5 0.1 5.9 5 1 2 7 7 7 2 Leucine Rich repeats (2 copies) Glyco_transf_52 PF07922.11 GBG89086.1 - 0.22 10.8 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 52 Phage_P2_GpE PF06528.12 GBG89086.1 - 0.22 11.1 0.4 0.43 10.2 0.4 1.5 1 0 0 1 1 1 0 Phage P2 GpE Ubiquitin_4 PF18036.1 GBG89087.1 - 7.3e-27 93.3 0.0 1.1e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain FtsJ PF01728.19 GBG89087.1 - 9.1e-20 71.5 0.0 8.1e-19 68.4 0.0 2.3 2 1 0 2 2 2 1 FtsJ-like methyltransferase FERM_N PF09379.10 GBG89087.1 - 0.18 11.8 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 FERM N-terminal domain ubiquitin PF00240.23 GBG89087.1 - 0.19 11.5 0.0 0.69 9.7 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family ATP-synt_D PF01813.17 GBG89089.1 - 2.6e-69 233.0 3.9 2.6e-69 233.0 3.9 1.8 2 0 0 2 2 2 1 ATP synthase subunit D Prefoldin PF02996.17 GBG89089.1 - 0.078 12.9 7.4 0.08 12.9 0.2 2.7 3 0 0 3 3 3 0 Prefoldin subunit DUF1054 PF06335.12 GBG89089.1 - 0.11 12.4 0.8 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) DUF1451 PF07295.11 GBG89089.1 - 0.76 9.8 3.5 0.43 10.6 0.8 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain TRAP_beta PF05753.14 GBG89090.1 - 7.1e-33 113.5 0.1 8.3e-33 113.3 0.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.18 GBG89090.1 - 0.023 15.0 0.3 0.082 13.2 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF11 Polyketide_cyc PF03364.20 GBG89091.1 - 5.4e-42 143.1 0.3 2.5e-21 76.3 0.0 3.1 3 0 0 3 3 3 2 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GBG89091.1 - 4.6e-16 59.4 0.0 1.4e-06 28.6 0.0 2.8 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 GBG89091.1 - 1.2e-06 28.3 0.0 0.007 16.1 0.0 2.5 2 0 0 2 2 2 2 Carbon monoxide dehydrogenase subunit G (CoxG) CDC45 PF02724.14 GBG89091.1 - 4.4 5.5 5.4 7.1 4.8 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Arg_repressor PF01316.21 GBG89093.1 - 0.016 14.9 0.3 0.025 14.3 0.3 1.3 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Ntox35 PF15534.6 GBG89093.1 - 0.091 13.2 0.4 0.13 12.7 0.4 1.3 1 0 0 1 1 1 0 Bacterial toxin 35 Chal_sti_synt_N PF00195.19 GBG89093.1 - 0.13 11.6 0.2 0.16 11.4 0.2 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain IL13 PF03487.13 GBG89093.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Interleukin-13 DUF5323 PF17257.2 GBG89094.1 - 4.4e-21 74.5 2.8 5.9e-21 74.1 2.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5323) zf-CCHC PF00098.23 GBG89095.1 - 8.5e-06 25.6 4.0 1.7e-05 24.7 4.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG89095.1 - 0.079 12.9 0.3 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG89095.1 - 0.57 10.1 4.1 1.2 9.0 4.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF572 PF04502.13 GBG89095.1 - 1.1 8.8 24.5 1.5 8.4 24.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC45 PF02724.14 GBG89099.1 - 0.15 10.3 35.5 0.23 9.7 35.5 1.4 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG89100.1 - 6.3e-32 109.6 0.0 3.2e-16 59.2 0.0 2.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89100.1 - 6.7e-29 100.3 0.0 1.6e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89100.1 - 1.3e-27 96.8 0.0 2e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG89100.1 - 0.0048 17.5 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease YCII PF03795.14 GBG89101.1 - 0.17 12.3 0.1 0.17 12.3 0.1 2.7 3 0 0 3 3 3 0 YCII-related domain EMC3_TMCO1 PF01956.16 GBG89101.1 - 0.9 9.3 6.5 0.45 10.2 0.1 2.9 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like TMPIT PF07851.13 GBG89101.1 - 2.8 7.1 10.9 0.22 10.7 2.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein Dimer_Tnp_hAT PF05699.14 GBG89104.1 - 0.00011 22.0 0.6 0.00023 20.9 0.6 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4311 PF14188.6 GBG89104.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) CENP-K PF11802.8 GBG89106.1 - 0.063 12.8 4.9 0.097 12.2 4.9 1.4 1 1 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 GBG89106.1 - 0.33 10.9 12.1 0.38 10.7 12.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CREPT PF16566.5 GBG89106.1 - 0.36 11.0 7.1 6.3 7.0 0.2 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4407 PF14362.6 GBG89106.1 - 3 7.1 23.3 8.1 5.7 23.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF659 PF04937.15 GBG89111.1 - 3.7e-33 114.5 0.0 3e-32 111.6 0.0 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89111.1 - 6.6e-05 22.6 0.3 0.00043 20.0 0.2 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Tho2 PF11262.8 GBG89111.1 - 0.048 12.9 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF659 PF04937.15 GBG89112.1 - 2.9e-33 114.9 0.1 2.5e-32 111.9 0.0 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89112.1 - 5.1e-05 23.0 0.3 0.00037 20.2 0.2 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Tho2 PF11262.8 GBG89112.1 - 0.041 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FBA PF04300.13 GBG89112.1 - 0.13 11.9 0.1 0.58 9.8 0.1 2.1 2 0 0 2 2 2 0 F-box associated region DUF2127 PF09900.9 GBG89113.1 - 0.097 12.9 1.5 0.86 9.9 1.5 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2127) PA PF02225.22 GBG89115.1 - 7.5e-09 35.5 0.0 1.9e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 PA domain EGF_CA PF07645.15 GBG89115.1 - 0.0024 18.0 15.1 0.0024 18.0 15.1 4.4 4 0 0 4 4 4 1 Calcium-binding EGF domain cEGF PF12662.7 GBG89115.1 - 0.011 15.6 6.6 0.011 15.6 6.6 4.2 4 0 0 4 4 4 0 Complement Clr-like EGF-like UBX PF00789.20 GBG89115.1 - 0.11 12.7 0.1 0.99 9.6 0.0 2.4 1 1 1 2 2 2 0 UBX domain EGF_3 PF12947.7 GBG89115.1 - 0.83 9.9 35.3 0.72 10.1 3.4 5.3 2 2 2 4 4 4 0 EGF domain BTB PF00651.31 GBG89116.1 - 3.6e-10 40.1 0.0 8.5e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain RT_RNaseH_2 PF17919.1 GBG89117.1 - 3.4e-70 232.4 0.3 3.2e-34 117.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89117.1 - 7.5e-51 170.8 1.0 6.9e-28 97.0 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89117.1 - 3.2e-37 126.4 3.2 3.4e-18 65.5 0.3 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG89117.1 - 2.6e-21 76.1 0.4 7.1e-11 42.0 0.1 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89117.1 - 1.6e-14 54.1 0.0 3e-12 46.8 0.0 2.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG89117.1 - 2e-05 24.7 0.9 0.0011 19.1 0.0 3.1 3 0 0 3 3 3 1 H2C2 zinc finger Chromo PF00385.24 GBG89117.1 - 0.026 14.4 0.4 0.062 13.2 0.4 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FdsD PF11390.8 GBG89117.1 - 0.041 14.2 0.2 5.8 7.3 0.0 3.0 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD GPS2_interact PF15784.5 GBG89117.1 - 0.075 13.5 0.6 1.6 9.3 0.6 2.5 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain EH_Signature PF15611.6 GBG89117.1 - 0.75 9.1 7.3 0.066 12.6 0.3 2.6 4 0 0 4 4 4 0 EH_Signature domain Cys_rich_CPXG PF14255.6 GBG89117.1 - 1.1 9.2 3.9 2.6 8.0 1.1 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG RT_RNaseH_2 PF17919.1 GBG89119.1 - 2.5e-19 69.1 0.0 7.1e-19 67.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89119.1 - 5.6e-11 42.7 0.0 2.2e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89119.1 - 7e-08 32.3 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89119.1 - 8e-08 32.8 0.0 3.1e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG89119.1 - 1.4e-07 31.3 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG89119.1 - 1.9e-05 25.1 0.0 9.2e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG89119.1 - 0.0056 16.9 0.0 0.025 14.9 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein WTX PF09422.10 GBG89119.1 - 0.077 12.1 2.1 0.12 11.4 2.1 1.2 1 0 0 1 1 1 0 WTX protein IL28A PF15177.6 GBG89119.1 - 0.84 9.5 8.5 0.56 10.0 6.2 1.9 2 0 0 2 2 2 0 Interleukin-28A TMF_TATA_bd PF12325.8 GBG89119.1 - 1.3 9.3 7.1 0.14 12.4 1.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding RT_RNaseH_2 PF17919.1 GBG89120.1 - 2.8e-10 40.1 0.0 8.4e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89120.1 - 4.7e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89120.1 - 5.7e-05 23.7 0.0 0.00018 22.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG89120.1 - 0.0005 19.7 0.0 0.00084 18.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89120.1 - 0.0056 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG89120.1 - 0.015 15.9 0.0 0.054 14.1 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG89120.1 - 0.077 13.3 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG89122.1 - 8.9e-33 113.7 0.0 1.4e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89122.1 - 3.2e-20 72.0 0.0 7.1e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89122.1 - 4.1e-10 39.6 0.0 4.1e-10 39.6 0.0 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG89122.1 - 1.8e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase eIF-1a PF01176.19 GBG89122.1 - 0.003 17.3 0.1 0.0064 16.3 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Chromo PF00385.24 GBG89122.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG89123.1 - 2.5e-17 63.1 0.0 5.4e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89123.1 - 5.7e-09 36.2 0.0 1.5e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG89123.1 - 0.0012 19.1 2.6 0.0025 18.0 0.2 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG89123.1 - 0.014 15.1 3.4 0.027 14.2 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) RVT_1 PF00078.27 GBG89124.1 - 2.2e-17 63.3 0.0 4.8e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89124.1 - 4.9e-09 36.4 0.0 1.3e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG89124.1 - 0.0011 19.2 2.7 0.0021 18.3 0.3 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG89124.1 - 0.0092 15.7 0.6 0.024 14.4 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RVT_1 PF00078.27 GBG89125.1 - 2.9e-30 105.4 0.1 5.4e-30 104.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG89125.1 - 7.9e-15 54.7 0.1 1.8e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89125.1 - 1.5e-08 34.8 0.1 6.1e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG89125.1 - 2.3e-07 31.0 0.7 5e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG89125.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF484 PF04340.12 GBG89125.1 - 0.54 9.9 5.8 0.63 9.7 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF484 RT_RNaseH_2 PF17919.1 GBG89126.1 - 4.7e-35 119.6 0.4 1.4e-34 118.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89126.1 - 1.6e-28 99.0 0.2 5.1e-28 97.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG89126.1 - 7.9e-24 84.3 0.0 1.6e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CENP-Q PF13094.6 GBG89126.1 - 0.021 15.0 3.2 0.074 13.3 0.9 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.15 GBG89126.1 - 0.58 10.0 8.2 1.3 8.9 8.2 1.6 1 0 0 1 1 1 0 Septum formation initiator AAA_13 PF13166.6 GBG89126.1 - 9.5 4.7 7.8 7.3 5.1 2.5 2.5 3 0 0 3 3 3 0 AAA domain RVT_1 PF00078.27 GBG89127.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Golgin_A5 PF09787.9 GBG89129.1 - 0.00066 19.2 29.5 0.00066 19.2 29.5 2.6 1 1 1 2 2 2 1 Golgin subfamily A member 5 Trehalose_PPase PF02358.16 GBG89129.1 - 0.0084 15.3 2.1 0.011 14.9 1.0 1.7 1 1 0 1 1 1 1 Trehalose-phosphatase SOTI PF17079.5 GBG89129.1 - 1.4 9.4 4.8 6.5 7.2 0.2 3.1 2 1 0 3 3 3 0 Male-specific protein scotti PI_PP_I PF18363.1 GBG89129.1 - 1.7 8.9 5.4 2.6 8.3 0.7 3.1 1 1 3 4 4 4 0 Phosphoinositide phosphatase insertion domain DUF948 PF06103.11 GBG89129.1 - 1.9 8.8 13.9 0.39 11.0 1.0 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) GIT_CC PF16559.5 GBG89129.1 - 3.3 7.6 23.1 0.13 12.2 0.6 4.4 1 1 3 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor RNaseH_like PF04308.12 GBG89129.1 - 5.3 7.0 8.2 9.7 6.1 1.8 2.5 2 0 0 2 2 2 0 Ribonuclease H-like JIP_LZII PF16471.5 GBG89129.1 - 7.6 6.8 45.9 0.11 12.6 5.4 6.3 3 2 3 6 6 6 0 JNK-interacting protein leucine zipper II PRIMA1 PF16101.5 GBG89130.1 - 4.5 7.3 8.5 13 5.8 8.5 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ribosomal_L34e PF01199.18 GBG89131.1 - 1e-41 141.1 6.7 1.5e-41 140.6 6.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e PRODH PF18327.1 GBG89131.1 - 0.026 14.7 0.1 0.043 14.0 0.1 1.3 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain FhuF_C PF11575.8 GBG89131.1 - 0.25 11.3 5.9 2.3 8.2 0.1 3.0 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain RINGv PF12906.7 GBG89132.1 - 0.48 10.6 3.3 5.6 7.2 0.2 2.4 2 0 0 2 2 2 0 RING-variant domain RAI1 PF08652.11 GBG89133.1 - 1.9e-22 79.2 0.0 4.3e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease RAM PF15320.6 GBG89134.1 - 0.067 13.8 3.8 0.11 13.1 3.8 1.3 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein E1-E2_ATPase PF00122.20 GBG89135.1 - 1e-17 64.3 0.0 2.1e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GBG89135.1 - 3.4e-16 60.2 0.0 3.4e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GBG89135.1 - 9.8e-08 32.0 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GBG89135.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GBG89136.1 - 7.8e-18 64.6 0.0 1.6e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GBG89136.1 - 3.4e-16 60.2 0.0 3.4e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GBG89136.1 - 9.8e-08 32.0 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GBG89136.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-HC5HC2H PF13771.6 GBG89137.1 - 5.2e-11 42.6 3.7 5.2e-11 42.6 3.7 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GBG89137.1 - 7.1e-08 32.6 2.0 7.1e-08 32.6 2.0 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain BRCT PF00533.26 GBG89137.1 - 0.00021 21.6 0.0 0.00043 20.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 GBG89137.1 - 0.0015 18.3 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 GBG89137.1 - 0.0021 18.0 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 GBG89137.1 - 0.077 13.4 0.0 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain PHD PF00628.29 GBG89137.1 - 6.7 6.7 7.0 1.6 8.6 2.7 2.4 2 0 0 2 2 2 0 PHD-finger RPW8 PF05659.11 GBG89138.1 - 0.0012 18.5 6.5 0.052 13.2 1.2 3.0 2 2 1 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 V-SNARE_C PF12352.8 GBG89138.1 - 0.0019 18.4 1.3 0.0019 18.4 1.3 2.4 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GBG89138.1 - 0.0022 17.9 6.7 0.0028 17.5 0.8 3.2 2 2 2 4 4 4 1 Sec20 Globin PF00042.22 GBG89138.1 - 0.0027 18.3 1.1 0.55 10.8 0.2 2.7 2 1 1 3 3 3 1 Globin EzrA PF06160.12 GBG89138.1 - 0.003 15.8 2.9 0.003 15.8 2.9 2.3 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Prominin PF05478.11 GBG89138.1 - 0.0047 15.0 0.7 0.0047 15.0 0.7 2.0 2 0 0 2 2 2 1 Prominin Occludin_ELL PF07303.13 GBG89138.1 - 0.0079 16.9 0.4 0.0079 16.9 0.4 2.5 3 1 0 3 3 2 1 Occludin homology domain Helo_like_N PF17111.5 GBG89138.1 - 0.0087 15.4 1.1 0.0087 15.4 1.1 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Sigma70_ner PF04546.13 GBG89138.1 - 0.0095 15.8 4.4 0.061 13.2 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, non-essential region ZYG-11_interact PF05884.12 GBG89138.1 - 0.026 13.9 0.9 0.03 13.7 0.1 1.5 2 0 0 2 2 2 0 Interactor of ZYG-11 DUF1759 PF03564.15 GBG89138.1 - 0.044 13.7 2.0 0.19 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Laminin_II PF06009.12 GBG89138.1 - 0.099 12.7 7.5 1.6 8.8 1.5 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF3970 PF13113.6 GBG89138.1 - 0.11 12.7 3.9 22 5.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) Cob_adeno_trans PF01923.18 GBG89138.1 - 0.18 11.9 2.3 8.4 6.5 0.1 2.3 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Fib_alpha PF08702.10 GBG89138.1 - 0.57 10.4 11.2 0.11 12.7 2.5 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 GBG89138.1 - 0.8 9.7 4.9 11 6.0 0.4 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DegS PF05384.11 GBG89138.1 - 0.8 9.2 7.9 4.6 6.7 0.3 3.0 2 2 1 3 3 3 0 Sensor protein DegS TMPIT PF07851.13 GBG89138.1 - 1 8.6 8.5 2.1 7.5 3.5 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 GBG89138.1 - 1.2 9.4 9.1 19 5.6 3.5 3.6 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 GBG89138.1 - 1.3 9.5 10.5 5.5 7.4 2.3 2.9 2 2 0 2 2 2 0 Syntaxin-like protein I_LWEQ PF01608.17 GBG89138.1 - 1.4 9.1 10.6 0.77 10.0 1.7 2.3 2 0 0 2 2 2 0 I/LWEQ domain DUF883 PF05957.13 GBG89138.1 - 2.2 8.9 6.4 3.9 8.1 0.4 3.0 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) MCU PF04678.13 GBG89138.1 - 2.4 8.2 4.6 3.2 7.8 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter V-SNARE PF05008.15 GBG89138.1 - 3.1 8.2 8.3 3.1 8.2 4.3 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF148 PF02520.17 GBG89138.1 - 3.9 7.6 7.5 4.2 7.5 2.7 2.6 2 1 1 3 3 3 0 Domain of unknown function DUF148 AKNA PF12443.8 GBG89138.1 - 3.9 8.2 8.8 1.7 9.4 1.4 3.0 2 2 1 3 3 3 0 AT-hook-containing transcription factor Med30 PF11315.8 GBG89138.1 - 5.7 7.1 8.6 1.3 9.2 2.1 2.3 2 1 0 2 2 2 0 Mediator complex subunit 30 FliT PF05400.13 GBG89138.1 - 7.6 7.4 7.4 4.6 8.1 4.0 2.3 2 1 0 2 2 2 0 Flagellar protein FliT Helicase_C PF00271.31 GBG89139.1 - 2.3e-15 56.9 0.0 4.4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GBG89139.1 - 5.8e-06 25.7 0.0 9.1e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 E7 PF00527.18 GBG89139.1 - 1.1 9.5 5.8 9.4 6.5 2.1 2.7 2 0 0 2 2 2 0 E7 protein, Early protein SNF2_N PF00176.23 GBG89140.1 - 4e-37 127.7 0.1 2.3e-25 89.1 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain PSII PF00421.19 GBG89140.1 - 2e-08 33.4 0.1 3.2e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Photosystem II protein ResIII PF04851.15 GBG89140.1 - 0.00059 19.9 0.0 0.067 13.2 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEK_C PF08766.11 GBG89140.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain HALZ PF02183.18 GBG89141.1 - 0.019 15.2 1.3 0.067 13.4 1.3 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 GBG89141.1 - 0.026 14.6 3.1 0.12 12.4 3.1 2.2 1 0 0 1 1 1 0 Basic region leucine zipper Transferase PF02458.15 GBG89141.1 - 0.048 12.3 0.0 0.088 11.4 0.0 1.4 1 0 0 1 1 1 0 Transferase family DUF2385 PF09539.10 GBG89141.1 - 0.051 14.1 0.2 1.2 9.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) DivIC PF04977.15 GBG89141.1 - 0.14 12.0 2.0 0.39 10.5 2.0 1.7 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 GBG89141.1 - 0.2 11.8 1.5 0.54 10.4 1.5 1.7 1 0 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 GBG89141.1 - 0.21 12.1 2.8 0.97 9.9 2.8 2.1 1 0 0 1 1 1 0 Cell division protein ZapB PIG-L PF02585.17 GBG89141.1 - 0.93 10.1 3.1 3.4 8.3 0.3 2.8 3 0 0 3 3 3 0 GlcNAc-PI de-N-acetylase RT_RNaseH_2 PF17919.1 GBG89142.1 - 1.5e-35 121.2 0.0 2.2e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89142.1 - 1.4e-31 108.9 0.2 2.5e-31 108.1 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG89143.1 - 2e-34 118.6 0.3 2e-34 118.6 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG89143.1 - 0.015 15.4 0.3 0.16 12.1 0.1 2.4 2 0 0 2 2 2 0 Integrase core domain Dimer_Tnp_hAT PF05699.14 GBG89143.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG89144.1 - 5.7e-37 126.9 0.0 9.9e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89144.1 - 0.0039 17.0 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NR_Repeat PF14046.6 GBG89144.1 - 0.024 14.8 0.4 0.024 14.8 0.4 2.8 3 0 0 3 3 3 0 Nuclear receptor repeat zf-BED PF02892.15 GBG89144.1 - 0.034 14.2 0.4 0.083 12.9 0.4 1.7 1 0 0 1 1 1 0 BED zinc finger DUF659 PF04937.15 GBG89145.1 - 5e-14 52.4 0.8 6.5e-14 52.1 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RskA PF10099.9 GBG89145.1 - 0.17 12.2 8.9 0.3 11.4 8.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Dimer_Tnp_hAT PF05699.14 GBG89145.1 - 0.19 11.5 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region SapB_2 PF03489.17 GBG89146.1 - 0.076 13.1 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 2 zf-CCHC PF00098.23 GBG89147.1 - 3e-07 30.2 1.8 7.3e-07 29.0 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG89147.1 - 0.00057 19.5 0.3 0.029 13.9 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG89147.1 - 0.0029 17.4 3.5 0.0039 17.0 1.1 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG89147.1 - 0.056 13.4 0.4 0.14 12.1 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Macoilin PF09726.9 GBG89147.1 - 0.31 9.5 13.1 0.48 8.9 13.1 1.2 1 0 0 1 1 1 0 Macoilin family FapA PF03961.13 GBG89147.1 - 0.52 8.9 11.8 1 7.9 11.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A eIF3g PF12353.8 GBG89147.1 - 0.95 9.9 20.1 0.15 12.5 0.2 2.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Vfa1 PF08432.10 GBG89147.1 - 1.6 9.1 18.4 3.2 8.1 18.4 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Endonuc_Holl PF10107.9 GBG89147.1 - 2.2 8.1 14.5 6.2 6.7 14.5 1.7 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase RR_TM4-6 PF06459.12 GBG89147.1 - 3.1 7.6 14.3 6.2 6.6 14.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RsbU_N PF08673.10 GBG89148.1 - 0.011 15.8 0.5 0.019 15.0 0.5 1.3 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain IQ PF00612.27 GBG89149.1 - 0.0065 16.2 0.4 0.0065 16.2 0.4 3.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif SDA1 PF05285.12 GBG89151.1 - 0.00017 21.1 1.6 0.0003 20.4 1.6 1.3 1 0 0 1 1 1 1 SDA1 FAM176 PF14851.6 GBG89151.1 - 0.076 12.7 6.2 0.46 10.1 0.2 2.6 2 0 0 2 2 2 0 FAM176 family BSP_II PF05432.11 GBG89151.1 - 0.27 10.9 26.8 0.049 13.3 22.6 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 GBG89151.1 - 0.31 9.1 14.4 0.45 8.5 14.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi MPP6 PF10175.9 GBG89151.1 - 0.62 10.6 9.0 6.9 7.2 3.8 2.4 2 0 0 2 2 2 0 M-phase phosphoprotein 6 RNA_polI_A34 PF08208.11 GBG89151.1 - 0.88 9.6 6.3 1.8 8.6 6.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med8 PF10232.9 GBG89151.1 - 2.9 7.4 4.6 12 5.4 1.1 2.5 3 0 0 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 BUD22 PF09073.10 GBG89151.1 - 5.2 6.3 10.6 0.3 10.4 5.3 1.6 2 0 0 2 2 2 0 BUD22 CENP-B_dimeris PF09026.10 GBG89151.1 - 5.7 7.4 20.5 6.1 7.3 2.9 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RT_RNaseH_2 PF17919.1 GBG89152.1 - 4.5e-29 100.4 0.0 1e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89152.1 - 2.2e-28 98.6 0.1 4.8e-28 97.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CaMKII_AD PF08332.10 GBG89152.1 - 5.3e-24 84.8 0.0 1.3e-23 83.5 0.0 1.7 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain ADK PF00406.22 GBG89152.1 - 2.6e-19 69.8 0.6 3.4e-18 66.2 0.0 2.9 3 0 0 3 3 3 1 Adenylate kinase AAA_17 PF13207.6 GBG89152.1 - 3.2e-11 43.8 0.0 3.2e-11 43.8 0.0 4.1 3 1 0 3 3 3 1 AAA domain RVT_1 PF00078.27 GBG89152.1 - 7e-11 42.1 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_lysozyme PF00959.19 GBG89152.1 - 0.1 13.1 0.4 2.2 8.7 0.0 2.8 3 0 0 3 3 3 0 Phage lysozyme SH3_16 PF18348.1 GBG89152.1 - 0.32 10.8 1.7 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain Phage_GPO PF05929.11 GBG89152.1 - 0.35 10.4 0.0 0.35 10.4 0.0 4.1 3 1 0 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase Retrotrans_gag PF03732.17 GBG89153.1 - 0.0013 19.0 5.0 0.0022 18.2 0.0 3.4 3 1 0 3 3 3 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG89153.1 - 0.0052 17.4 1.7 0.0052 17.4 1.7 3.2 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 GBG89153.1 - 0.019 15.4 1.3 0.28 11.7 0.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SPARC_Ca_bdg PF10591.9 GBG89153.1 - 7.5 6.9 7.3 0.61 10.4 1.4 2.2 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region YfiO PF13525.6 GBG89154.1 - 0.0074 16.0 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Outer membrane lipoprotein SPO22 PF08631.10 GBG89154.1 - 0.043 13.3 0.0 1.7 8.1 0.0 2.5 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like V-SNARE PF05008.15 GBG89154.1 - 0.07 13.5 1.1 0.86 10.0 0.1 2.7 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus PET117 PF15786.5 GBG89155.1 - 1.5 9.1 6.2 4.6 7.6 4.2 2.5 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial dDENN PF03455.19 GBG89156.1 - 0.0056 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 dDENN domain LMBR1 PF04791.16 GBG89156.1 - 0.37 9.7 4.8 0.63 8.9 4.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein RVT_1 PF00078.27 GBG89157.1 - 5.8e-29 101.2 0.1 1.2e-28 100.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG89157.1 - 4.8e-20 71.4 0.2 1.5e-19 69.8 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89157.1 - 1.4e-16 60.8 0.0 4e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89157.1 - 0.00026 21.1 0.0 0.0015 18.7 0.0 2.4 2 0 0 2 2 2 1 H2C2 zinc finger Chromo PF00385.24 GBG89157.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1564 PF07600.11 GBG89157.1 - 0.019 14.6 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) RT_RNaseH_2 PF17919.1 GBG89157.1 - 0.084 12.9 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89158.1 - 1.1e-32 112.0 0.0 2.1e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89158.1 - 7.6e-32 110.6 0.1 1.4e-31 109.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89158.1 - 3.3e-29 101.3 0.1 6e-29 100.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89158.1 - 7.7e-19 67.6 0.1 2.2e-18 66.1 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG89158.1 - 0.00018 21.7 0.0 0.00065 19.9 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG89158.1 - 0.00031 20.9 0.0 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DENN PF02141.21 GBG89158.1 - 0.011 15.7 0.1 0.04 13.9 0.0 1.9 2 0 0 2 2 2 0 DENN (AEX-3) domain RT_RNaseH_2 PF17919.1 GBG89159.1 - 2.8e-32 110.7 0.0 5.5e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89159.1 - 3.7e-32 111.7 0.1 5.9e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89159.1 - 4.2e-29 100.9 0.1 7.6e-29 100.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89159.1 - 1.3e-19 70.0 0.1 3.1e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89159.1 - 0.0054 16.9 0.0 0.022 14.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG89159.1 - 0.017 15.3 0.0 0.096 12.9 0.0 2.4 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG89160.1 - 1.5e-25 89.1 0.0 4.6e-25 87.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89160.1 - 2.1e-23 82.6 0.0 7.2e-23 80.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89160.1 - 1.1e-18 67.5 0.1 2.8e-18 66.3 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89160.1 - 0.0003 21.0 0.0 0.00085 19.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain TRPM_tetra PF16519.5 GBG89160.1 - 0.0064 16.6 0.2 3.2 7.9 0.0 2.6 2 0 0 2 2 2 2 Tetramerisation domain of TRPM DUF421 PF04239.12 GBG89160.1 - 0.13 12.0 0.4 0.31 10.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF421) DENN PF02141.21 GBG89161.1 - 1.1e-29 103.7 0.2 1.8e-29 103.0 0.2 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain DUF659 PF04937.15 GBG89162.1 - 7.7e-11 42.1 0.6 1.9e-10 40.8 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89162.1 - 4.8e-05 23.1 0.4 0.00016 21.4 0.4 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region rve PF00665.26 GBG89162.1 - 6.3e-05 23.1 0.1 0.00018 21.7 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG89162.1 - 0.024 14.9 1.7 0.074 13.3 0.1 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG89165.1 - 2.1e-37 128.8 0.0 4.5e-37 127.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG89165.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG89165.1 - 0.088 12.7 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase RVT_1 PF00078.27 GBG89166.1 - 1.2e-21 77.2 0.0 2e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5095 PF17016.5 GBG89166.1 - 0.032 13.9 0.7 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) GTP1_OBG PF01018.22 GBG89169.1 - 0.0095 15.5 1.1 0.024 14.3 1.1 1.6 1 0 0 1 1 1 1 GTP1/OBG SNF2_N PF00176.23 GBG89175.1 - 2.4e-24 85.7 0.0 5.1e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 GBG89175.1 - 0.029 14.4 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DBINO PF13892.6 GBG89175.1 - 3.5 8.0 9.2 0.18 12.2 3.0 2.0 2 0 0 2 2 2 0 DNA-binding domain Integrase_H2C2 PF17921.1 GBG89176.1 - 3.3e-18 65.5 0.1 6.1e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89176.1 - 3.2e-16 59.6 0.0 8.3e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89176.1 - 0.026 14.7 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 GBG89176.1 - 0.088 12.6 0.0 0.32 10.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain DUF2052 PF09747.9 GBG89177.1 - 0.51 10.4 21.8 0.69 10.0 21.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AAA_11 PF13086.6 GBG89177.1 - 1.1 8.9 6.6 1.3 8.7 6.6 1.0 1 0 0 1 1 1 0 AAA domain DUF4604 PF15377.6 GBG89177.1 - 1.2 9.5 18.4 1.3 9.5 18.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) BSP_II PF05432.11 GBG89177.1 - 2.4 7.8 28.9 3 7.5 28.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 GBG89177.1 - 4.6 5.2 19.3 4.9 5.1 19.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop53 PF07767.11 GBG89177.1 - 4.8 6.5 24.3 5.3 6.3 24.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Fmp27 PF10344.9 GBG89177.1 - 7.4 4.5 5.6 6.8 4.6 5.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 BTB PF00651.31 GBG89179.1 - 1.5e-18 67.1 0.1 1.4e-14 54.3 0.0 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 GBG89179.1 - 0.044 13.9 0.6 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 BTB And C-terminal Kelch BTB PF00651.31 GBG89180.1 - 2.5e-19 69.5 0.1 4.7e-15 55.8 0.0 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 GBG89180.1 - 0.012 15.8 0.7 0.078 13.1 0.1 2.3 1 1 0 2 2 2 0 BTB And C-terminal Kelch RVT_1 PF00078.27 GBG89181.1 - 1.2e-29 103.4 0.1 2.1e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89181.1 - 3.4e-25 88.0 0.0 9.7e-25 86.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89181.1 - 1.8e-23 82.8 0.0 6e-23 81.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG89181.1 - 0.0015 18.8 2.2 0.0061 16.8 0.1 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein Pkinase PF00069.25 GBG89182.1 - 2.8e-44 151.5 0.0 3.6e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG89182.1 - 3e-44 151.2 0.0 3.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG89182.1 - 6.3e-05 23.0 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG89182.1 - 0.0011 17.9 0.0 0.0014 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase B2 PF11473.8 GBG89182.1 - 0.018 14.8 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 RNA binding protein B2 YukC PF10140.9 GBG89182.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Retrotrans_gag PF03732.17 GBG89183.1 - 0.0073 16.6 0.5 0.083 13.2 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein Beta_helix PF13229.6 GBG89184.1 - 2.7e-06 27.3 0.6 5.4e-06 26.3 0.6 1.6 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG89184.1 - 4.8 7.9 8.0 14 6.4 0.0 4.5 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF659 PF04937.15 GBG89185.1 - 2.2e-14 53.6 0.0 3.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89185.1 - 0.098 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG89186.1 - 2.3e-08 34.1 0.0 4.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89186.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Myb_DNA-bind_4 PF13837.6 GBG89187.1 - 1.1e-06 29.0 1.1 2.2e-05 24.8 0.5 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG89187.1 - 0.029 14.4 2.4 0.046 13.8 1.6 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG89188.1 - 1.5e-31 109.2 0.0 4.6e-31 107.6 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89188.1 - 1.4e-14 54.2 0.0 2.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89188.1 - 0.00081 19.1 0.2 0.92 9.1 0.0 2.6 3 0 0 3 3 3 2 Transposase DDE domain HTH_48 PF17906.1 GBG89188.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 HTH domain in Mos1 transposase RVT_1 PF00078.27 GBG89189.1 - 2.1e-30 105.9 0.0 3.6e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89189.1 - 1.6e-15 57.0 0.0 3.1e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89189.1 - 0.00014 22.1 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Plasmodium_Vir PF05795.11 GBG89189.1 - 3.4 7.0 15.9 4.8 6.5 15.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein HSP20 PF00011.21 GBG89190.1 - 3.8e-29 100.8 0.1 5.2e-29 100.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG89190.1 - 1e-09 37.8 0.1 2.4e-09 36.6 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 GBG89191.1 - 6.9e-28 96.8 0.0 8.5e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG89191.1 - 4.2e-09 35.8 0.1 9.6e-09 34.7 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Beta_helix PF13229.6 GBG89192.1 - 9e-11 41.9 0.5 3e-10 40.2 0.4 1.8 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG89192.1 - 0.034 13.4 0.2 0.094 12.0 0.2 1.6 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) HSP20 PF00011.21 GBG89193.1 - 3.2e-30 104.3 0.1 4.5e-30 103.8 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG89193.1 - 1.9e-09 36.9 0.1 4.5e-09 35.7 0.1 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 GBG89193.1 - 0.15 12.2 0.0 1.6 8.9 0.0 2.1 2 0 0 2 2 2 0 FKBP26_C-terminal HSP20 PF00011.21 GBG89194.1 - 4.5e-30 103.8 0.1 5.8e-30 103.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG89194.1 - 1.3e-09 37.5 0.1 2.8e-09 36.4 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 GBG89194.1 - 0.088 12.9 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 FKBP26_C-terminal HSP20 PF00011.21 GBG89195.1 - 9.2e-30 102.8 0.1 1.3e-29 102.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG89195.1 - 2e-09 36.9 0.1 4.7e-09 35.7 0.1 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 GBG89195.1 - 0.14 12.3 0.0 1.6 8.9 0.0 2.1 2 0 0 2 2 2 0 FKBP26_C-terminal SNAP PF14938.6 GBG89196.1 - 1.2e-20 74.2 9.8 1.3e-20 74.0 9.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 GBG89196.1 - 1.2e-05 25.5 10.4 0.043 14.1 1.9 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG89196.1 - 0.0002 21.2 11.9 0.35 11.1 0.5 5.4 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GBG89196.1 - 0.00024 20.6 1.5 0.00028 20.4 1.5 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 GBG89196.1 - 0.0015 19.0 4.1 0.033 14.7 0.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat NSF PF02071.20 GBG89196.1 - 0.0081 16.7 15.1 0.42 11.5 0.5 5.5 5 1 0 5 5 4 2 Aromatic-di-Alanine (AdAR) repeat TPR_7 PF13176.6 GBG89196.1 - 0.011 15.8 2.8 19 5.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG89196.1 - 0.011 15.5 11.4 0.55 10.1 0.6 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG89196.1 - 0.029 14.6 2.4 2 8.7 0.0 3.6 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Cpn60_TCP1 PF00118.24 GBG89196.1 - 0.07 11.7 0.1 0.088 11.4 0.1 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family TPR_11 PF13414.6 GBG89196.1 - 0.32 10.7 4.0 39 4.1 0.1 3.7 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.6 GBG89196.1 - 0.33 11.3 13.0 2.6 8.5 0.7 5.0 4 1 2 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 GBG89196.1 - 3.4 7.8 10.4 47 4.2 0.1 4.5 4 2 1 5 5 5 0 MIT (microtubule interacting and transport) domain DnaJ PF00226.31 GBG89197.1 - 1.2e-19 70.2 0.4 2.9e-19 69.0 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 GBG89197.1 - 3.3e-07 29.9 4.8 0.0023 17.7 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG89197.1 - 0.0092 16.0 4.3 5.4 7.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat SUIM_assoc PF16619.5 GBG89197.1 - 0.2 11.8 14.2 0.12 12.5 10.7 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HAGH_C PF16123.5 GBG89197.1 - 0.33 11.5 2.1 0.88 10.1 0.1 2.7 3 0 0 3 3 3 0 Hydroxyacylglutathione hydrolase C-terminus CRPA PF05745.11 GBG89198.1 - 0.069 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Nop14 PF04147.12 GBG89199.1 - 0.012 13.8 4.2 0.013 13.7 4.2 1.0 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG89199.1 - 0.26 11.6 10.4 0.45 10.8 10.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 GBG89199.1 - 1.3 8.4 11.3 1.7 8.0 11.3 1.1 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 GBG89199.1 - 2.6 7.8 6.2 3.6 7.3 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GBG89199.1 - 4.2 5.5 8.1 5.3 5.2 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 GBG89199.1 - 5.9 6.2 14.6 8.5 5.7 14.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RVT_1 PF00078.27 GBG89200.1 - 2.8e-15 56.5 0.0 4.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89200.1 - 9e-11 41.7 0.0 2.3e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89200.1 - 0.0034 17.6 0.0 0.0085 16.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SlyX PF04102.12 GBG89200.1 - 0.094 13.3 0.2 0.094 13.3 0.2 3.2 4 0 0 4 4 4 0 SlyX RT_RNaseH PF17917.1 GBG89201.1 - 4.4e-29 100.9 0.2 9.1e-29 99.8 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89201.1 - 3.1e-22 78.5 0.1 7.8e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89201.1 - 1.8e-19 69.6 0.1 4.1e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89201.1 - 1.4e-15 57.6 0.0 3.9e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89201.1 - 0.00034 20.8 0.1 0.0019 18.4 0.0 2.3 3 0 0 3 3 3 1 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG89201.1 - 0.0035 17.3 0.6 0.0095 15.9 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF1564 PF07600.11 GBG89201.1 - 0.008 15.9 0.5 0.03 14.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) zf-CCHC_4 PF14392.6 GBG89201.1 - 0.44 10.3 1.8 0.96 9.2 0.8 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 GBG89201.1 - 0.74 10.0 4.7 2.2 8.5 4.7 1.9 1 0 0 1 1 1 0 Zinc knuckle Aldedh PF00171.22 GBG89202.1 - 2.2e-53 181.4 0.3 2.7e-53 181.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 GBG89204.1 - 5.8e-22 77.8 0.0 6.5e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RabGAP-TBC PF00566.18 GBG89205.1 - 2.3e-25 89.5 0.0 3.9e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RVT_1 PF00078.27 GBG89206.1 - 7.4e-33 113.9 0.1 1.4e-32 113.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89206.1 - 1.9e-14 53.8 0.0 4.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF2385 PF09539.10 GBG89206.1 - 0.14 12.7 0.1 2.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) RVT_1 PF00078.27 GBG89207.1 - 1.1e-27 97.0 0.1 2.4e-27 95.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HIP1_clath_bdg PF16515.5 GBG89207.1 - 0.017 15.7 0.9 0.017 15.7 0.9 3.9 4 1 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 VESA1_N PF12785.7 GBG89207.1 - 2.7 6.9 7.0 4.3 6.2 7.0 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Peptidase_S10 PF00450.22 GBG89208.1 - 7.8e-103 345.1 0.0 9e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Asp_protease_2 PF13650.6 GBG89209.1 - 0.0017 18.9 0.0 0.003 18.1 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG89210.1 - 4.1e-27 95.1 0.2 1.3e-26 93.5 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89210.1 - 6.9e-25 87.0 0.0 1.9e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89210.1 - 2.4e-23 82.4 0.0 5.9e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89210.1 - 8e-19 67.5 1.2 2.5e-18 65.9 1.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG89210.1 - 3.2e-07 30.6 0.0 5.2e-06 26.6 0.0 2.7 1 1 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG89210.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG89210.1 - 0.0017 18.6 0.0 0.0017 18.6 0.0 3.3 4 0 0 4 4 4 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG89210.1 - 0.039 14.2 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger NPV_P10 PF05531.12 GBG89210.1 - 0.47 11.0 3.1 0.93 10.0 0.3 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1180 PF06679.12 GBG89212.1 - 2.7 8.4 22.0 2.6 8.5 6.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) RT_RNaseH_2 PF17919.1 GBG89213.1 - 3.8e-16 59.0 0.0 8e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89213.1 - 6e-11 42.3 0.2 1e-10 41.6 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89213.1 - 7.1e-08 32.7 0.0 1.9e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG89213.1 - 6 5.0 7.3 8 4.6 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein FCD PF07729.12 GBG89214.1 - 0.53 10.7 4.2 3.4 8.1 0.4 2.8 2 1 1 3 3 3 0 FCD domain RT_RNaseH PF17917.1 GBG89216.1 - 8.5e-22 77.4 0.0 1.9e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89216.1 - 2.1e-19 69.4 0.0 3.9e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG89216.1 - 1.1 9.5 3.1 0.41 10.8 0.7 1.6 2 0 0 2 2 2 0 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG89217.1 - 3e-27 95.2 0.0 5.2e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89217.1 - 3.9e-14 52.7 0.0 6.1e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89217.1 - 0.042 13.5 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG89218.1 - 2.6e-08 34.1 1.1 2.6e-08 34.1 1.1 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG89218.1 - 0.03 14.7 1.4 0.098 13.0 0.2 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-CCHC PF00098.23 GBG89219.1 - 0.00011 22.1 3.2 0.00022 21.1 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG89219.1 - 0.19 11.6 1.3 0.39 10.6 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF572 PF04502.13 GBG89219.1 - 0.29 10.7 22.0 0.4 10.3 22.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2205 PF10224.9 GBG89219.1 - 0.31 11.1 9.0 0.11 12.5 5.2 2.2 1 1 1 2 2 2 0 Short coiled-coil protein PBP_sp32 PF07222.12 GBG89219.1 - 1.3 8.5 16.4 1.4 8.3 11.3 2.2 2 0 0 2 2 2 0 Proacrosin binding protein sp32 RNAse_A_bac PF18431.1 GBG89219.1 - 5.7 7.9 7.2 21 6.1 7.2 2.0 1 1 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain V_ATPase_I PF01496.19 GBG89219.1 - 6.2 4.6 8.0 6.8 4.5 8.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Iron_permease PF04120.12 GBG89219.1 - 6.6 6.5 8.4 19 5.0 8.4 1.8 1 0 0 1 1 1 0 Low affinity iron permease Hemerythrin PF01814.23 GBG89220.1 - 6.7e-27 94.7 32.8 1.6e-09 38.5 8.4 4.7 4 1 1 5 5 5 3 Hemerythrin HHE cation binding domain zinc_ribbon_6 PF14599.6 GBG89220.1 - 4.9e-24 84.1 0.2 4.9e-24 84.1 0.2 2.9 2 0 0 2 2 2 1 Zinc-ribbon zf-CHY PF05495.12 GBG89220.1 - 1.6e-17 63.8 22.4 1.6e-17 63.8 22.4 3.9 3 0 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 GBG89220.1 - 5.3e-07 29.9 11.2 5.3e-07 29.9 11.2 4.7 4 1 0 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 GBG89220.1 - 3.8e-05 23.5 7.7 3.8e-05 23.5 7.7 3.5 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG89220.1 - 7e-05 22.6 7.6 7e-05 22.6 7.6 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG89220.1 - 0.00018 21.4 10.3 0.00018 21.4 10.3 5.2 3 2 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG89220.1 - 0.0018 18.3 7.5 0.0018 18.3 7.5 2.9 3 0 0 3 3 3 1 RING-type zinc-finger RVT_1 PF00078.27 GBG89221.1 - 4.6e-13 49.2 0.0 1e-12 48.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG89222.1 - 2.7e-13 50.1 0.0 4.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89222.1 - 1.4e-05 24.8 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SDA1 PF05285.12 GBG89222.1 - 1.1 8.6 20.9 1.6 8.1 20.9 1.2 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG89225.1 - 7.7e-27 94.3 0.0 1.6e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF563 PF04577.14 GBG89225.1 - 1.3e-18 67.9 0.2 1.2e-09 38.6 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF563) RT_RNaseH_2 PF17919.1 GBG89225.1 - 6.5e-16 58.2 0.0 1.6e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89225.1 - 4.2e-06 26.6 0.0 8.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89225.1 - 4.9e-05 23.9 0.0 0.00033 21.3 0.0 2.4 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89225.1 - 0.00011 22.6 0.0 0.00034 21.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG89225.1 - 0.0016 18.7 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG89225.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG89226.1 - 1.3e-12 47.6 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89226.1 - 1.6e-10 41.2 0.0 3.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain GTP_EFTU PF00009.27 GBG89227.1 - 1.2e-26 93.5 0.0 2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GBG89227.1 - 5.4e-06 26.5 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GBG89227.1 - 1.3e-05 24.7 0.3 0.00036 20.0 0.3 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 GBG89227.1 - 0.00018 21.8 0.0 0.00051 20.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Gtr1_RagA PF04670.12 GBG89227.1 - 0.00062 19.2 0.0 0.0015 17.9 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region cobW PF02492.19 GBG89227.1 - 0.0018 17.9 0.4 0.022 14.3 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 GBG89227.1 - 0.035 13.9 0.1 17 5.1 0.0 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 GBG89227.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit PetM PF08041.11 GBG89228.1 - 8.2e-08 31.7 1.0 1.3e-07 31.1 1.0 1.3 1 0 0 1 1 1 1 PetM family of cytochrome b6f complex subunit 7 RbcS PF12338.8 GBG89228.1 - 5 7.4 13.1 0.88 9.8 8.4 2.1 1 1 1 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit PhosphMutase PF10143.9 GBG89230.1 - 2.2e-52 177.4 0.0 3.2e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 GBG89230.1 - 6.6e-25 87.9 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF4410 PF14366.6 GBG89230.1 - 0.005 16.7 0.0 0.0089 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4410) Phosphodiest PF01663.22 GBG89230.1 - 0.15 11.7 0.0 0.6 9.6 0.0 1.9 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase RVT_1 PF00078.27 GBG89231.1 - 8.1e-28 97.4 0.0 1.3e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89231.1 - 8.8e-24 83.5 0.0 2.4e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89231.1 - 1.7e-21 76.5 0.0 4.6e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89231.1 - 3.5e-18 65.5 0.4 1.5e-17 63.4 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG89231.1 - 6.9e-11 42.4 0.0 2.1e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG89231.1 - 0.0018 18.5 1.2 0.061 13.6 0.0 3.4 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG89231.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG89231.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DDE_Tnp_4 PF13359.6 GBG89234.1 - 7.6e-24 84.2 0.0 1.2e-20 73.7 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89234.1 - 9e-08 32.0 0.0 4.8e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG89234.1 - 0.069 13.5 0.0 0.25 11.8 0.0 1.9 1 0 0 1 1 1 0 Transposase DDE domain Ank_4 PF13637.6 GBG89237.1 - 2.2e-22 79.1 1.4 4.3e-08 33.6 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GBG89237.1 - 1.3e-21 77.0 1.3 8.6e-16 58.3 0.3 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GBG89237.1 - 1.3e-19 70.0 6.6 3.4e-11 43.1 0.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GBG89237.1 - 5.5e-16 58.2 4.4 1.1e-07 32.0 0.2 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GBG89237.1 - 7.1e-13 47.5 1.5 1.6e-05 24.9 0.1 2.9 3 1 0 3 3 3 2 Ankyrin repeat GRP PF07172.11 GBG89240.1 - 0.39 11.4 15.1 0.46 11.2 15.1 1.1 1 0 0 1 1 1 0 Glycine rich protein family RVT_1 PF00078.27 GBG89244.1 - 3.8e-41 141.0 0.6 1.5e-26 93.3 0.1 2.6 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89247.1 - 2.2e-19 69.3 0.2 1.6e-18 66.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89247.1 - 7.6e-19 68.1 0.1 9.1e-18 64.6 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89247.1 - 2.7e-18 66.2 0.0 6.9e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89247.1 - 4.6e-11 42.7 0.3 3.4e-10 39.9 0.0 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG89249.1 - 4.8e-11 42.9 0.1 1e-10 41.9 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG89249.1 - 0.099 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG89250.1 - 9.5e-56 186.0 1.7 1.1e-30 105.6 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89250.1 - 7.9e-52 174.0 1.8 4.7e-27 94.3 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89250.1 - 3.8e-37 126.2 0.5 4.6e-18 65.1 0.1 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG89250.1 - 5e-11 42.8 0.2 1.5e-08 34.8 0.0 3.4 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG89250.1 - 0.00037 20.7 0.0 0.25 11.6 0.0 2.8 2 0 0 2 2 2 2 H2C2 zinc finger Integrin_b_cyt PF08725.11 GBG89250.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RT_RNaseH_2 PF17919.1 GBG89251.1 - 3.8e-23 81.4 0.4 2.4e-22 78.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89251.1 - 8.8e-23 80.6 0.1 2.2e-22 79.3 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89251.1 - 1e-16 60.7 0.0 2.7e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89251.1 - 5.1e-10 39.6 0.2 2.6e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Integrin_b_cyt PF08725.11 GBG89251.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RVT_1 PF00078.27 GBG89253.1 - 4.4e-35 121.2 0.1 7.4e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) REV PF00424.18 GBG89253.1 - 0.42 10.7 3.1 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) CBP_BcsN PF17038.5 GBG89254.1 - 0.053 12.9 0.2 0.14 11.5 0.2 1.7 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN PTPRCAP PF15713.5 GBG89254.1 - 2.4 8.4 16.5 0.5 10.6 9.8 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SlyX PF04102.12 GBG89257.1 - 0.11 13.2 1.5 0.38 11.4 1.5 2.0 1 0 0 1 1 1 0 SlyX bZIP_1 PF00170.21 GBG89257.1 - 1.7 8.8 10.3 0.58 10.3 6.3 2.4 2 1 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 GBG89257.1 - 3.4 7.5 10.9 0.047 13.5 2.5 2.2 2 1 1 3 3 3 0 Septum formation initiator zf-CCHC_6 PF15288.6 GBG89258.1 - 0.35 10.7 2.4 0.7 9.8 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG89258.1 - 2.9 8.1 5.4 5.7 7.2 5.4 1.5 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG89259.1 - 9.6e-08 32.5 0.0 3.5e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89259.1 - 8.8e-07 29.5 0.0 2.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG89259.1 - 7.7e-06 26.1 0.0 2.4e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG89259.1 - 9.2e-06 25.5 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89259.1 - 0.00026 20.8 0.0 0.00071 19.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG89259.1 - 0.0026 18.0 0.4 0.0096 16.2 0.4 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG89259.1 - 0.26 11.1 0.6 0.72 9.7 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) CHAT PF12770.7 GBG89260.1 - 9.9e-34 117.1 0.0 5.9e-33 114.5 0.0 2.0 1 1 1 2 2 2 1 CHAT domain Rab5-bind PF09311.11 GBG89260.1 - 0.016 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Rabaptin-like protein Retrotrans_gag PF03732.17 GBG89261.1 - 0.00054 20.2 0.1 0.00054 20.2 0.1 4.1 4 1 0 4 4 4 2 Retrotransposon gag protein DUF3006 PF11213.8 GBG89261.1 - 0.18 12.1 1.1 0.37 11.0 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) HIP1_clath_bdg PF16515.5 GBG89261.1 - 3.9 8.1 20.9 0.056 14.1 2.6 3.6 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 rve PF00665.26 GBG89262.1 - 2.9e-10 40.4 0.0 8.4e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG89262.1 - 1.5e-06 28.8 0.0 2.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89262.1 - 4.9e-06 27.0 0.0 9.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG89262.1 - 6.6e-06 25.9 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89262.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG89262.1 - 0.00014 21.4 0.3 0.00068 19.2 0.0 2.0 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vir_act_alpha_C PF10400.9 GBG89262.1 - 0.029 15.1 2.9 0.065 13.9 0.6 2.6 3 0 0 3 3 3 0 Virulence activator alpha C-term Chromo PF00385.24 GBG89262.1 - 0.052 13.5 0.1 0.092 12.7 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_4 PF13837.6 GBG89263.1 - 1.2e-05 25.6 1.3 1.9e-05 24.9 1.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG89263.1 - 0.0046 17.0 0.2 0.0083 16.2 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain rpo132 PF12415.8 GBG89265.1 - 3.6e-06 26.1 0.0 0.25 10.7 0.0 3.3 3 0 0 3 3 3 2 Poxvirus DNA dependent RNA polymerase Alanine_zipper PF11839.8 GBG89265.1 - 0.019 15.3 20.4 0.019 15.3 20.4 1.9 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Cwf_Cwc_15 PF04889.12 GBG89265.1 - 1.5 8.5 29.7 0.081 12.7 24.1 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Asp_protease_2 PF13650.6 GBG89266.1 - 0.00029 21.4 0.1 0.0008 20.0 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89266.1 - 0.0008 19.9 0.2 0.0022 18.5 0.2 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG89266.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG89266.1 - 9 6.6 5.7 1.5 9.0 1.5 2.0 2 0 0 2 2 2 0 Zinc knuckle DUF659 PF04937.15 GBG89268.1 - 3.1e-15 56.3 0.0 5.4e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG89268.1 - 7.4e-09 35.8 0.0 9.5e-07 29.0 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG89268.1 - 2.2e-06 27.5 0.0 4.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG89268.1 - 3.7e-06 26.6 0.0 7.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG89268.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease eIF-1a PF01176.19 GBG89268.1 - 0.0025 17.6 0.1 0.0074 16.1 0.1 1.8 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Asp_protease_2 PF13650.6 GBG89268.1 - 0.0036 17.9 0.0 0.011 16.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89268.1 - 0.0089 16.6 0.0 0.025 15.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 GBG89268.1 - 0.024 14.4 0.0 0.1 12.4 0.0 2.2 1 0 0 1 1 1 0 Integrase core domain ZapB PF06005.12 GBG89268.1 - 0.26 11.8 2.6 1 9.8 2.6 2.0 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 GBG89268.1 - 0.34 11.2 1.1 0.9 9.8 1.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Herpes_capsid PF06112.11 GBG89268.1 - 6.2 6.9 13.6 1.1 9.3 0.1 3.0 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein BUD22 PF09073.10 GBG89269.1 - 0.0084 15.5 14.0 0.011 15.2 14.0 1.1 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 GBG89269.1 - 0.042 13.3 14.6 0.07 12.5 14.6 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG89269.1 - 1.6 6.8 13.6 2.1 6.5 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH PF17917.1 GBG89270.1 - 1.6e-22 79.8 0.0 3.1e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89270.1 - 1.8e-22 79.3 0.0 4e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89270.1 - 7.4e-17 61.6 0.1 8.8e-10 38.5 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG89270.1 - 1.1e-07 31.7 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89270.1 - 1.2e-07 32.3 0.0 3.7e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89270.1 - 7.8e-05 23.2 0.0 0.00018 22.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG89270.1 - 0.0061 16.3 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG89271.1 - 1.6e-25 89.0 0.0 4.5e-25 87.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89271.1 - 8e-22 77.5 0.2 7.9e-21 74.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Alpha_Helical PF18489.1 GBG89271.1 - 0.24 11.6 1.3 2.3 8.4 1.1 2.2 1 1 1 2 2 2 0 Alpha helical domain BLOC1_2 PF10046.9 GBG89271.1 - 2.9 8.2 13.0 0.065 13.5 3.8 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GBG89271.1 - 4.8 7.7 5.8 42 4.7 0.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 GBG89271.1 - 8.4 6.9 6.6 45 4.5 1.6 3.1 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Adaptin_binding PF10199.9 GBG89271.1 - 9.9 6.8 14.2 9 6.9 11.7 2.1 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RNA_pol_Rpb1_2 PF00623.20 GBG89272.1 - 2.2e-53 180.9 0.0 4.4e-53 179.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GBG89272.1 - 3e-34 118.2 0.0 6.1e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 GBG89272.1 - 1.4e-30 106.8 0.2 3.4e-24 85.8 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RT_RNaseH_2 PF17919.1 GBG89273.1 - 2.5e-25 88.4 0.0 5e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89273.1 - 5.7e-23 81.2 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89273.1 - 2.2e-17 62.9 0.2 5.6e-17 61.6 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain APG17 PF04108.12 GBG89273.1 - 0.0032 16.6 0.0 0.0061 15.7 0.0 1.4 1 0 0 1 1 1 1 Autophagy protein Apg17 RVT_1 PF00078.27 GBG89273.1 - 0.0065 16.0 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG89273.1 - 0.0074 16.5 0.0 0.2 11.9 0.0 2.6 2 0 0 2 2 2 1 H2C2 zinc finger Acyl-CoA_dh_C PF12806.7 GBG89273.1 - 0.029 14.5 0.1 5.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Retrotrans_gag PF03732.17 GBG89274.1 - 3.3e-06 27.3 5.6 0.036 14.3 0.0 3.8 3 0 0 3 3 3 2 Retrotransposon gag protein Perilipin PF03036.16 GBG89274.1 - 0.74 8.8 11.6 1.2 8.1 11.6 1.3 1 0 0 1 1 1 0 Perilipin family RNR_Alpha PF17975.1 GBG89274.1 - 1.7 9.2 4.9 1.8 9.1 0.1 2.4 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain DUF4192 PF13830.6 GBG89274.1 - 2.5 8.1 17.6 1.4 8.9 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Baculo_PEP_C PF04513.12 GBG89274.1 - 2.7 8.0 7.8 3.5 7.7 0.2 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 GBG89274.1 - 3.9 7.9 13.6 0.06 13.7 1.5 3.6 3 3 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NDK PF00334.19 GBG89275.1 - 2.8e-41 140.7 0.0 3.7e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase F-box PF00646.33 GBG89276.1 - 5.7e-07 29.3 0.9 3e-06 27.0 0.9 2.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GBG89276.1 - 5.7e-07 29.3 0.3 1.3e-06 28.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GBG89276.1 - 0.08 13.4 1.9 38 4.9 0.0 5.1 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) RNA_pol_N PF01194.17 GBG89277.1 - 1.4e-19 70.1 0.1 1.6e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Cluap1 PF10234.9 GBG89278.1 - 6.1e-105 350.4 10.1 8.2e-105 350.0 10.1 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lebercilin PF15619.6 GBG89278.1 - 0.0078 15.9 15.5 0.0078 15.9 15.5 1.7 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF1839 PF08893.10 GBG89278.1 - 0.017 14.3 0.4 0.37 9.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1839) DUF3037 PF11236.8 GBG89278.1 - 0.026 14.9 4.9 0.12 12.8 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) DUF4795 PF16043.5 GBG89278.1 - 0.11 12.1 8.3 0.17 11.5 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) CENP-Q PF13094.6 GBG89278.1 - 0.14 12.4 16.0 0.49 10.6 3.3 2.6 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fez1 PF06818.15 GBG89278.1 - 0.32 11.4 18.6 0.18 12.3 15.4 2.0 1 1 1 2 2 2 0 Fez1 HAUS-augmin3 PF14932.6 GBG89278.1 - 0.65 9.5 13.1 9 5.8 13.1 2.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 GBG89278.1 - 0.74 9.9 5.3 0.23 11.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 GBG89278.1 - 0.96 9.2 4.7 2.1 8.1 0.4 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3781 PF12636.7 GBG89278.1 - 1.1 9.1 2.8 2.7 7.9 0.1 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3781) CC2-LZ PF16516.5 GBG89278.1 - 1.6 9.2 12.6 0.29 11.5 2.7 3.2 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DASH_Spc19 PF08287.11 GBG89278.1 - 1.7 8.5 17.0 0.029 14.3 4.0 2.5 1 1 1 2 2 2 0 Spc19 Uds1 PF15456.6 GBG89278.1 - 5.6 7.1 13.6 6.9 6.8 0.5 2.9 2 1 0 2 2 2 0 Up-regulated During Septation HrpB7 PF09486.10 GBG89278.1 - 6.9 7.0 16.0 1.2 9.5 9.7 2.5 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) gag-asp_proteas PF13975.6 GBG89280.1 - 3.4e-05 24.3 0.0 9.1e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89280.1 - 8.9e-05 23.1 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG89280.1 - 0.00072 19.8 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89280.1 - 0.0015 18.3 0.2 0.005 16.6 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG89280.1 - 0.0073 16.1 1.0 0.012 15.5 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG89280.1 - 0.008 16.4 1.0 0.021 15.1 1.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_6 PF15288.6 GBG89280.1 - 0.16 11.8 0.5 0.37 10.7 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG89280.1 - 0.23 11.6 1.5 0.39 10.9 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Acetyltransf_1 PF00583.25 GBG89281.1 - 8.1e-15 55.1 0.1 1.6e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GBG89281.1 - 2e-08 34.2 0.3 2.9e-08 33.7 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG89281.1 - 3e-07 30.3 0.1 5.2e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 GBG89281.1 - 3e-07 30.7 0.1 5.2e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GBG89281.1 - 0.01 16.0 0.6 0.016 15.3 0.6 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GBG89281.1 - 0.031 15.0 0.1 0.06 14.0 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SRP-alpha_N PF04086.13 GBG89281.1 - 0.039 13.9 3.1 0.056 13.4 3.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Acetyltransf_9 PF13527.7 GBG89281.1 - 0.051 13.6 0.1 0.093 12.8 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 GBG89281.1 - 0.085 12.6 0.4 0.32 10.7 0.1 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 GBG89281.1 - 0.14 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF659 PF04937.15 GBG89282.1 - 1.3e-25 90.1 0.7 1.9e-25 89.5 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Mfa2 PF08842.10 GBG89284.1 - 0.18 11.4 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 CRS1_YhbY PF01985.21 GBG89286.1 - 3.1e-55 184.3 7.9 8.4e-19 67.5 0.0 4.8 4 1 0 4 4 4 4 CRS1 / YhbY (CRM) domain DHHC PF01529.20 GBG89287.1 - 9.6e-39 132.6 13.4 9.6e-39 132.6 13.4 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase FtsH_ext PF06480.15 GBG89287.1 - 0.07 13.5 0.2 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 FtsH Extracellular Pkinase_Tyr PF07714.17 GBG89288.1 - 8.4e-50 169.5 0.0 1.4e-49 168.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG89288.1 - 5.5e-49 166.9 0.0 7.6e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PIP49_C PF12260.8 GBG89288.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 RT_RNaseH_2 PF17919.1 GBG89289.1 - 1.8e-34 117.8 0.0 4.4e-34 116.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89289.1 - 1.2e-30 105.8 0.8 4.4e-30 104.1 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89289.1 - 1.1e-25 90.5 0.0 2e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG89289.1 - 2.2e-15 56.5 0.2 4.6e-15 55.5 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG89289.1 - 0.0015 18.2 7.9 0.77 9.3 0.0 2.2 2 0 0 2 2 2 2 Phage capsid scaffolding protein (GPO) serine peptidase NPV_P10 PF05531.12 GBG89289.1 - 0.34 11.4 3.9 7 7.2 0.1 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 GBG89289.1 - 1.1 9.7 12.4 0.36 11.3 0.2 3.1 3 0 0 3 3 3 0 Snapin/Pallidin FlxA PF14282.6 GBG89289.1 - 8.8 6.4 15.5 6.1 6.9 3.9 2.9 3 0 0 3 3 3 0 FlxA-like protein TIMELESS PF04821.14 GBG89290.1 - 0.35 10.1 1.8 1.5 8.1 0.1 2.0 2 0 0 2 2 2 0 Timeless protein CDC45 PF02724.14 GBG89290.1 - 10 4.3 7.4 12 4.1 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Retrotrans_gag PF03732.17 GBG89291.1 - 0.024 14.9 0.8 0.2 11.9 0.2 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein Rx_N PF18052.1 GBG89291.1 - 0.028 14.7 0.3 7.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Rx N-terminal domain DUF1664 PF07889.12 GBG89291.1 - 0.33 11.0 3.6 2.1 8.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) T4bSS_IcmS PF12608.8 GBG89292.1 - 0.34 11.3 0.1 0.34 11.3 0.1 2.2 2 0 0 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment RT_RNaseH_2 PF17919.1 GBG89293.1 - 5.4e-34 116.2 0.1 1e-33 115.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89293.1 - 1.4e-30 106.4 0.1 2.3e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89293.1 - 2.2e-28 98.6 0.1 3.8e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG89293.1 - 0.00037 21.0 0.0 0.0012 19.3 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG89293.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.12 GBG89293.1 - 0.11 12.3 0.1 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative peptidase (DUF1758) RVT_1 PF00078.27 GBG89294.1 - 2.5e-35 122.0 0.2 5e-35 121.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89294.1 - 5.3e-30 103.4 0.0 9.1e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89294.1 - 2.9e-23 82.1 0.0 5.7e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase N6_N4_Mtase PF01555.18 GBG89295.1 - 2.2e-05 24.3 0.0 3.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 DNA methylase CoA_binding_2 PF13380.6 GBG89296.1 - 0.085 13.3 0.0 0.47 11.0 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain HrpB7 PF09486.10 GBG89297.1 - 0.19 12.1 20.7 0.026 14.9 15.6 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Retrotrans_gag PF03732.17 GBG89297.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.5 2 1 1 3 3 3 0 Retrotransposon gag protein DUF4806 PF16064.5 GBG89297.1 - 0.23 11.8 2.1 63 4.0 0.9 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4806) NPV_P10 PF05531.12 GBG89297.1 - 0.27 11.7 1.7 30 5.2 0.0 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CAP_N PF01213.19 GBG89297.1 - 2.3 7.6 6.8 0.29 10.6 0.8 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4140 PF13600.6 GBG89297.1 - 7.6 7.0 14.1 11 6.5 0.5 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) RVT_1 PF00078.27 GBG89298.1 - 0.071 12.6 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_60s PF00428.19 GBG89299.1 - 1.2e-20 73.8 17.2 8.1e-20 71.2 17.2 1.9 1 1 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 GBG89299.1 - 0.052 12.0 0.1 0.072 11.5 0.1 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein rve PF00665.26 GBG89301.1 - 0.0029 17.8 0.0 0.0079 16.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF484 PF04340.12 GBG89301.1 - 0.07 12.8 6.0 0.16 11.7 5.8 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF484 Retrotrans_gag PF03732.17 GBG89301.1 - 0.16 12.3 0.8 29 5.0 0.1 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein FAM76 PF16046.5 GBG89302.1 - 0.066 12.6 6.3 0.1 11.9 6.3 1.2 1 0 0 1 1 1 0 FAM76 protein Occludin_ELL PF07303.13 GBG89302.1 - 0.1 13.3 6.7 6.2 7.6 0.0 3.4 4 1 0 4 4 4 0 Occludin homology domain Cep57_MT_bd PF06657.13 GBG89302.1 - 0.17 12.4 0.1 0.17 12.4 0.1 3.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 KH_8 PF17903.1 GBG89303.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 GBG89303.1 - 0.00024 20.9 0.2 0.00045 20.0 0.2 1.4 1 0 0 1 1 1 1 KH domain DNA_pol_phi PF04931.13 GBG89305.1 - 4 5.4 25.0 7.1 4.6 25.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi Asp_protease_2 PF13650.6 GBG89306.1 - 4.3e-05 24.1 0.0 0.00012 22.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89306.1 - 0.00026 21.5 0.1 0.00091 19.8 0.0 2.0 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease Phage_fiber_2 PF03406.13 GBG89306.1 - 0.26 10.9 0.7 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Phage tail fibre repeat RNase_HII PF01351.18 GBG89306.1 - 3 7.6 4.6 16 5.2 0.3 2.6 1 1 1 3 3 3 0 Ribonuclease HII gag-asp_proteas PF13975.6 GBG89307.1 - 0.00026 21.5 0.0 0.00059 20.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89307.1 - 0.0075 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG89307.1 - 0.018 15.1 2.6 0.031 14.3 2.6 1.4 1 0 0 1 1 1 0 Zinc knuckle ATE_N PF04376.13 GBG89307.1 - 0.058 13.8 0.5 0.86 10.0 0.0 2.8 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus DUF659 PF04937.15 GBG89308.1 - 8.5e-32 110.1 0.0 1.2e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RRN3 PF05327.11 GBG89308.1 - 0.67 8.4 1.7 0.99 7.9 1.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GBG89308.1 - 6.2 4.8 10.2 12 3.9 10.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Ran_BP1 PF00638.18 GBG89309.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RanBP1 domain RVT_1 PF00078.27 GBG89313.1 - 2.6e-08 33.6 0.0 5.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89314.1 - 4.6e-31 106.8 0.0 1.2e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89314.1 - 3.2e-28 98.1 0.1 6.4e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89315.1 - 7.8e-29 100.1 0.0 1.3e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89315.1 - 1.9e-24 85.6 0.0 3.9e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG89315.1 - 0.011 15.5 0.6 0.041 13.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) RT_RNaseH_2 PF17919.1 GBG89316.1 - 4.7e-26 90.7 0.0 1.2e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89316.1 - 2.7e-25 89.2 0.0 5.3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89316.1 - 1.3e-23 83.3 0.0 5.2e-23 81.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG89316.1 - 4e-07 30.6 0.0 9.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89316.1 - 3.3e-06 27.6 0.0 8.1e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG89316.1 - 0.00047 19.9 0.0 0.00092 19.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG89316.1 - 0.00069 19.5 6.2 0.0087 15.9 0.1 3.0 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG89316.1 - 0.00085 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG89318.1 - 2.9e-05 24.3 7.0 0.0013 19.0 0.1 4.6 4 1 0 4 4 4 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG89318.1 - 0.049 14.2 1.0 0.049 14.2 1.0 3.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cdh1_DBD_1 PF18196.1 GBG89318.1 - 0.3 11.4 4.5 0.92 9.8 0.8 2.9 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 ADIP PF11559.8 GBG89318.1 - 6.7 6.8 10.7 2.7 8.1 0.2 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding RVT_1 PF00078.27 GBG89319.1 - 2.7e-28 99.0 0.1 4.3e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG89319.1 - 0.0014 19.2 0.0 0.0024 18.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89319.1 - 0.086 13.5 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Urotensin_II PF02083.15 GBG89320.1 - 0.18 11.6 0.5 0.38 10.5 0.5 1.5 1 0 0 1 1 1 0 Urotensin II RT_RNaseH_2 PF17919.1 GBG89321.1 - 7e-25 87.0 0.0 2.4e-24 85.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89321.1 - 1.8e-15 57.1 0.0 3.9e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG89321.1 - 0.00055 19.2 6.4 0.0026 17.0 0.0 2.4 2 0 0 2 2 2 1 Autophagy protein Apg17 CLZ PF16526.5 GBG89321.1 - 0.0021 18.4 1.9 0.07 13.5 0.3 3.1 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RVT_1 PF00078.27 GBG89321.1 - 0.0055 16.2 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89321.1 - 0.019 15.2 0.0 0.019 15.2 0.0 2.5 3 0 0 3 3 3 0 Integrase core domain HXXSHH PF07586.11 GBG89321.1 - 1.2 8.7 10.8 2.3 7.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1552) RT_RNaseH PF17917.1 GBG89322.1 - 9.7e-29 99.7 0.1 2.2e-28 98.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89322.1 - 4e-22 78.1 0.1 9.5e-22 76.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89322.1 - 2.8e-20 72.2 0.3 6.3e-20 71.0 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89322.1 - 4.4e-07 30.1 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89322.1 - 0.0038 17.4 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_3 PF13917.6 GBG89322.1 - 0.016 15.1 1.8 0.042 13.8 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG89322.1 - 0.022 15.0 0.0 0.022 15.0 0.0 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 GBG89322.1 - 0.11 12.3 1.3 1.8 8.3 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle PI_PP_C PF18365.1 GBG89325.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain EIF_2_alpha PF07541.12 GBG89325.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit FlaC_arch PF05377.11 GBG89327.1 - 0.044 14.2 0.1 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CK2S PF15011.6 GBG89327.1 - 0.1 12.5 0.6 5.6 6.8 0.0 2.5 3 0 0 3 3 3 0 Casein Kinase 2 substrate NPV_P10 PF05531.12 GBG89327.1 - 0.14 12.6 0.1 4.3 7.9 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 GBG89327.1 - 0.15 12.7 1.4 0.54 10.9 0.2 2.5 3 0 0 3 3 3 0 SlyX DUF948 PF06103.11 GBG89327.1 - 0.16 12.3 0.2 0.72 10.2 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PSK_trans_fac PF07704.11 GBG89327.1 - 1.3 9.8 6.6 0.83 10.5 1.8 2.5 1 1 1 2 2 2 0 Rv0623-like transcription factor RVT_1 PF00078.27 GBG89328.1 - 3.3e-28 98.7 0.6 8e-28 97.5 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89328.1 - 5e-23 81.0 0.0 1.1e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89328.1 - 1e-22 80.4 0.0 2.7e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89328.1 - 6e-17 61.5 0.3 1.3e-16 60.4 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89328.1 - 5.8e-09 36.2 0.1 2.5e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain DUF659 PF04937.15 GBG89330.1 - 2.9e-37 127.9 0.0 4.9e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG89331.1 - 2.1e-25 88.7 0.0 6e-25 87.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89331.1 - 1.4e-23 83.1 0.0 3.7e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89331.1 - 5.4e-16 58.4 0.1 1.4e-15 57.2 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89331.1 - 4.6e-08 33.3 0.0 1.6e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG89331.1 - 2.1e-06 28.3 0.0 4.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89331.1 - 5.9e-06 26.8 0.0 1.5e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG89331.1 - 8.2e-05 22.4 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89331.1 - 0.00019 21.2 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 GBG89331.1 - 0.00083 19.2 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG89331.1 - 0.037 14.3 0.0 0.17 12.2 0.0 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein GlyL_C PF12524.8 GBG89331.1 - 0.081 13.1 3.0 1.2 9.3 1.7 3.3 3 0 0 3 3 3 0 dsDNA virus glycoprotein L C terminal RVT_1 PF00078.27 GBG89332.1 - 0.00073 19.1 0.0 0.21 11.0 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89333.1 - 1.4e-22 79.6 0.0 6.2e-22 77.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89333.1 - 8e-21 74.3 0.0 4.1e-20 72.0 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG89333.1 - 6.4e-08 32.8 0.0 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG89333.1 - 5.2e-05 23.7 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89333.1 - 9.2e-05 23.0 0.0 0.00019 22.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 GBG89333.1 - 0.0055 16.5 0.0 0.033 14.0 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG89333.1 - 0.0057 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 GBG89333.1 - 0.01 16.1 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89333.1 - 0.026 14.3 0.1 0.067 13.0 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG89334.1 - 8.9e-31 106.3 0.0 1.5e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89334.1 - 2.9e-27 94.6 0.0 5.2e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG89334.1 - 1.8e-08 34.1 2.1 3.4e-08 33.2 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG89334.1 - 0.013 15.3 2.7 0.023 14.5 2.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG89335.1 - 0.0018 18.5 0.0 0.0089 16.3 0.0 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein Cytidylate_kin PF02224.18 GBG89335.1 - 0.016 15.0 0.3 0.037 13.8 0.2 1.6 2 0 0 2 2 2 0 Cytidylate kinase PTPRCAP PF15713.5 GBG89335.1 - 0.18 12.1 10.3 2.8 8.2 0.6 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated U3_snoRNA_assoc PF08297.11 GBG89335.1 - 3.6 8.4 14.7 1.2 9.9 2.2 2.6 2 0 0 2 2 2 0 U3 snoRNA associated RT_RNaseH_2 PF17919.1 GBG89336.1 - 8.2e-28 96.4 0.0 1.9e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89336.1 - 6.8e-25 87.4 0.0 2.9e-24 85.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG89336.1 - 0.0016 18.7 4.1 0.0061 16.8 0.0 3.4 3 1 0 3 3 3 1 Retrotransposon gag protein HIP1_clath_bdg PF16515.5 GBG89336.1 - 0.0068 17.0 2.6 0.0068 17.0 2.6 3.1 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 GBG89336.1 - 0.046 13.1 11.8 0.38 10.1 5.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 GBG89336.1 - 8.9 6.4 12.8 0.54 10.3 0.5 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Nop14 PF04147.12 GBG89337.1 - 0.11 10.7 34.5 0.12 10.5 34.5 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG89337.1 - 0.19 10.0 28.1 0.22 9.7 28.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 GBG89337.1 - 0.33 10.1 38.4 0.38 9.8 38.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 GBG89337.1 - 0.7 9.3 35.4 0.82 9.0 35.4 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 GBG89337.1 - 0.85 8.0 32.8 1 7.7 32.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Zip PF02535.22 GBG89337.1 - 1.1 8.4 9.2 1.2 8.3 9.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 GBG89337.1 - 3 7.6 18.6 4.2 7.1 18.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 GBG89337.1 - 3.1 6.3 32.0 3.6 6.0 32.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SpoIIP PF07454.11 GBG89337.1 - 3.8 6.9 11.7 4.3 6.7 11.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.10 GBG89337.1 - 4.3 7.6 16.9 5.7 7.2 16.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Plasmodium_Vir PF05795.11 GBG89337.1 - 6.9 6.0 9.8 8 5.8 9.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Paf1 PF03985.13 GBG89337.1 - 7.9 5.4 29.7 9.4 5.1 29.7 1.2 1 0 0 1 1 1 0 Paf1 zf-CCHC PF00098.23 GBG89338.1 - 9e-07 28.7 3.1 1.7e-06 27.8 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG89338.1 - 0.0065 16.3 1.0 0.014 15.2 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG89338.1 - 0.022 14.6 0.8 0.054 13.3 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG89338.1 - 0.025 14.6 0.3 0.025 14.6 0.3 1.8 2 0 0 2 2 2 0 Zinc knuckle Stevor PF17410.2 GBG89338.1 - 0.95 9.0 4.3 1.4 8.4 4.3 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame FA PF08736.11 GBG89338.1 - 1.7 8.8 9.3 4.3 7.5 0.3 3.6 3 0 0 3 3 3 0 FERM adjacent (FA) Retrotrans_gag PF03732.17 GBG89339.1 - 0.00014 22.0 4.3 0.00019 21.6 0.2 3.2 3 1 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.24 GBG89339.1 - 0.024 14.5 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TMEM247 PF15444.6 GBG89339.1 - 0.073 13.1 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 Caudo_TAP PF02413.17 GBG89339.1 - 1 9.5 9.2 0.9 9.7 0.8 2.9 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK p450 PF00067.22 GBG89340.1 - 1.2e-55 189.1 0.0 6.6e-52 176.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 THOC2_N PF16134.5 GBG89340.1 - 0.08 11.6 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus WD40 PF00400.32 GBG89341.1 - 4.8e-07 30.4 5.2 0.18 12.7 0.3 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 GBG89341.1 - 0.00054 18.7 0.1 0.0058 15.3 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GBG89341.1 - 0.039 14.3 0.3 4.7 7.6 0.0 3.7 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GBG89342.1 - 2.4e-06 28.1 11.7 0.55 11.2 0.0 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 GBG89342.1 - 0.011 14.4 2.0 0.079 11.6 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 tRNA_synthFbeta PF17759.1 GBG89343.1 - 1.4e-48 165.2 0.0 2.2e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 GBG89343.1 - 1.3e-24 86.2 0.3 9.9e-24 83.4 0.2 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 GBG89343.1 - 1.6e-23 83.3 0.0 2.8e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 GBG89343.1 - 2.6e-19 69.3 0.1 3e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain CAF1C_H4-bd PF12265.8 GBG89343.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Ribosomal_L20 PF00453.18 GBG89344.1 - 4.2e-25 87.9 2.7 9.2e-25 86.8 2.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L20 FAD_binding_3 PF01494.19 GBG89345.1 - 4.7e-16 59.0 0.2 8.8e-12 44.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GBG89345.1 - 0.018 15.3 0.5 0.11 12.7 0.0 2.7 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain ChAPs PF09295.10 GBG89346.1 - 0.063 12.3 0.3 2.8 6.8 0.0 2.3 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Goodbye PF17109.5 GBG89348.1 - 0.0003 21.2 1.6 0.13 12.7 0.1 2.9 1 1 2 3 3 3 2 fungal STAND N-terminal Goodbye domain ChlamPMP_M PF07548.11 GBG89348.1 - 1.4 8.8 9.9 7.4 6.5 4.7 2.6 1 1 1 2 2 2 0 Chlamydia polymorphic membrane protein middle domain DUF659 PF04937.15 GBG89350.1 - 1.4e-18 67.2 0.0 2.2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ASCH PF04266.14 GBG89351.1 - 0.024 15.2 2.0 0.035 14.7 0.1 2.1 1 1 1 2 2 2 0 ASCH domain ESM4 PF15952.5 GBG89351.1 - 0.38 11.2 0.1 0.38 11.2 0.1 2.2 1 1 1 2 2 2 0 Enhancer of split M4 family DUF659 PF04937.15 GBG89352.1 - 2.8e-12 46.8 0.0 4.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG89355.1 - 2.6e-14 53.4 1.7 5.4e-14 52.4 1.7 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG89355.1 - 1.3e-11 44.7 0.0 4.3e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG89355.1 - 1.3e-09 38.0 0.0 3.1e-08 33.6 0.0 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG89355.1 - 6.8e-06 26.0 0.3 1.5e-05 24.9 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rhamno_transf PF11316.8 GBG89355.1 - 0.0093 15.4 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 1 Putative rhamnosyl transferase rve_3 PF13683.6 GBG89355.1 - 0.04 13.7 0.1 0.25 11.1 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 GBG89355.1 - 0.063 13.5 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger EMC3_TMCO1 PF01956.16 GBG89356.1 - 0.0078 16.0 0.9 0.013 15.3 0.9 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Cwf_Cwc_15 PF04889.12 GBG89356.1 - 0.012 15.4 11.9 0.012 15.4 11.9 2.5 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GBG89356.1 - 1.3 8.3 19.8 2.1 7.6 19.8 1.3 1 0 0 1 1 1 0 BUD22 MORN PF02493.20 GBG89357.1 - 7.2e-34 113.7 36.7 0.00037 20.2 0.5 9.6 9 0 0 9 9 9 9 MORN repeat PRIMA1 PF16101.5 GBG89357.1 - 5.8 7.0 9.3 16 5.5 9.3 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-CCHC PF00098.23 GBG89358.1 - 0.19 11.9 3.4 0.45 10.7 1.9 2.2 2 0 0 2 2 2 0 Zinc knuckle PPDK_N PF01326.19 GBG89359.1 - 0.66 9.2 5.3 1.9 7.7 2.1 2.1 2 0 0 2 2 2 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain ALMT PF11744.8 GBG89359.1 - 1.1 8.0 6.2 1.5 7.6 6.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RVT_1 PF00078.27 GBG89360.1 - 1.6e-07 31.1 0.0 0.0055 16.2 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) IQCJ-SCHIP1 PF15157.6 GBG89363.1 - 0.077 12.8 0.4 4.2 7.2 0.4 2.2 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DDE_Tnp_4 PF13359.6 GBG89364.1 - 1.6e-25 89.6 0.0 2.6e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89364.1 - 1.4e-12 47.6 0.0 2.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89364.1 - 0.02 14.5 0.2 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG89364.1 - 0.14 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Pkinase_Tyr PF07714.17 GBG89365.1 - 1.4e-21 77.0 0.0 2.4e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG89365.1 - 7.5e-16 58.3 0.0 2e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain DUF659 PF04937.15 GBG89367.1 - 6.8e-19 68.2 0.0 1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) WAP PF00095.21 GBG89368.1 - 0.03 14.7 2.7 0.03 14.7 2.7 2.5 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF507 PF04368.13 GBG89369.1 - 0.0011 18.9 0.0 0.0066 16.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF507) RVT_1 PF00078.27 GBG89372.1 - 9.1e-08 31.9 0.0 1.1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YL1 PF05764.13 GBG89372.1 - 0.13 12.4 15.4 0.17 12.0 15.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 GBG89372.1 - 0.19 10.0 10.1 0.26 9.6 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG89372.1 - 0.31 10.4 11.8 0.4 10.1 11.8 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG89372.1 - 0.38 8.9 11.1 0.44 8.7 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4360 PF14273.6 GBG89373.1 - 6.3e-32 110.9 0.0 7.3e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG89374.1 - 1.1e-47 160.2 0.0 9.3e-24 83.4 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89374.1 - 9.1e-32 109.5 0.0 1.6e-17 63.7 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89374.1 - 3.2e-15 56.2 0.1 5.5e-10 39.1 0.0 3.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG89374.1 - 5.9e-08 32.6 0.0 1.6e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89374.1 - 8e-07 29.6 0.0 2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89374.1 - 4.8e-06 27.0 0.0 1.1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF3653 PF12375.8 GBG89374.1 - 0.026 14.6 0.0 16 5.7 0.0 2.8 2 0 0 2 2 2 0 Phage protein Asp_protease PF09668.10 GBG89374.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease AbrB_C PF18277.1 GBG89374.1 - 0.086 12.5 0.0 22 4.8 0.0 2.5 2 0 0 2 2 2 0 AbrB C-terminal domain Methyltransf_32 PF13679.6 GBG89374.1 - 6 6.8 5.8 42 4.1 0.1 3.1 3 0 0 3 3 3 0 Methyltransferase domain DUF4360 PF14273.6 GBG89375.1 - 1.3e-24 87.0 0.0 1.5e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG89376.1 - 8.1e-34 117.0 0.0 9.3e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) gag-asp_proteas PF13975.6 GBG89377.1 - 7.8e-08 32.8 0.0 1.5e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89377.1 - 8.5e-07 29.5 0.0 2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG89377.1 - 0.0012 18.6 0.4 0.0021 17.8 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG89377.1 - 0.031 14.6 0.0 0.085 13.2 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease SlyX PF04102.12 GBG89377.1 - 0.17 12.5 4.0 0.55 10.9 4.0 1.9 1 0 0 1 1 1 0 SlyX Asp_protease_2 PF13650.6 GBG89380.1 - 0.0032 18.1 0.0 0.011 16.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89380.1 - 0.11 13.1 0.0 0.37 11.4 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease TolA_bind_tri PF16331.5 GBG89380.1 - 0.82 9.8 4.6 2.1 8.5 4.6 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation zf-CCHC PF00098.23 GBG89381.1 - 0.068 13.3 1.9 0.14 12.3 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG89381.1 - 0.24 11.1 1.2 0.39 10.4 0.2 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like DUF4360 PF14273.6 GBG89382.1 - 4.3e-35 121.2 0.0 5.3e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RVT_1 PF00078.27 GBG89383.1 - 1.7e-05 24.5 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG89383.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89383.1 - 0.099 13.3 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG89383.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pinin_SDK_memA PF04696.13 GBG89383.1 - 0.62 10.1 7.6 0.062 13.4 2.2 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF4360 PF14273.6 GBG89384.1 - 3.6e-39 134.5 0.0 5.7e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Rossmann-like PF10727.9 GBG89384.1 - 0.015 15.2 0.3 0.029 14.2 0.3 1.4 1 0 0 1 1 1 0 Rossmann-like domain Retrotrans_gag PF03732.17 GBG89384.1 - 0.068 13.4 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 GBG89385.1 - 0.038 14.3 0.2 0.038 14.3 0.2 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein DUF2716 PF10898.8 GBG89385.1 - 0.17 12.3 0.4 0.66 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) DUF4360 PF14273.6 GBG89388.1 - 4.6e-36 124.3 0.0 7e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pkinase PF00069.25 GBG89389.1 - 7.9e-36 123.8 0.0 1.1e-34 120.1 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG89389.1 - 2.9e-32 112.0 0.0 8.9e-23 80.9 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 GBG89389.1 - 0.00093 19.2 0.0 0.024 14.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG89389.1 - 0.038 12.8 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Uroplakin_II PF07353.12 GBG89389.1 - 0.13 11.7 1.1 0.36 10.3 1.1 1.7 1 0 0 1 1 1 0 Uroplakin II Herpes_gE PF02480.16 GBG89389.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E rve PF00665.26 GBG89391.1 - 0.071 13.3 1.0 0.12 12.5 0.0 1.9 3 0 0 3 3 3 0 Integrase core domain gag-asp_proteas PF13975.6 GBG89392.1 - 0.0035 17.9 0.0 0.0066 17.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89392.1 - 0.067 13.9 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease NUP PF06516.11 GBG89392.1 - 0.25 10.5 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Pkinase PF00069.25 GBG89393.1 - 1.2e-35 123.2 0.0 4.5e-35 121.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG89393.1 - 1.3e-31 109.8 0.0 6.5e-22 78.0 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 GBG89393.1 - 0.14 12.1 0.0 0.97 9.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG89393.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ABC1 PF03109.16 GBG89393.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 ABC1 family zf-CCHC_4 PF14392.6 GBG89394.1 - 0.044 13.5 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG89394.1 - 0.066 13.3 0.5 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Phage_integrase PF00589.22 GBG89395.1 - 0.002 17.9 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family UQ_con PF00179.26 GBG89396.1 - 2.5e-41 140.6 0.0 3.5e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CCDC53 PF10152.9 GBG89396.1 - 2.8e-19 70.0 0.0 4.3e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Prok-E2_B PF14461.6 GBG89396.1 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GBG89396.1 - 0.073 13.4 0.0 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 RWD domain SPX PF03105.19 GBG89396.1 - 0.12 12.3 2.7 0.14 12.0 2.7 1.1 1 0 0 1 1 1 0 SPX domain Paramyx_P_V_C PF03210.13 GBG89396.1 - 0.21 11.3 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal RT_RNaseH_2 PF17919.1 GBG89397.1 - 1e-21 76.8 0.0 1.7e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89397.1 - 2.3e-20 72.8 0.0 3.7e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG89397.1 - 0.011 15.1 4.7 0.014 14.9 4.7 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG89397.1 - 0.13 11.9 5.7 0.2 11.4 5.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG89397.1 - 0.43 8.8 5.0 0.6 8.3 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG89397.1 - 2.2 6.4 9.7 2.9 6.0 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family FKBP_C PF00254.28 GBG89398.1 - 6.3e-21 74.5 0.0 9.6e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RVT_1 PF00078.27 GBG89399.1 - 1.1e-26 93.7 0.1 1.8e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG89399.1 - 2.2e-12 46.7 0.0 4.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 GBG89399.1 - 0.00023 21.1 1.7 0.00023 21.1 1.7 1.8 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG89399.1 - 0.17 12.5 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease LAP1C PF05609.12 GBG89400.1 - 9.6 5.2 9.9 13 4.8 9.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) LAP1C PF05609.12 GBG89401.1 - 1.3 8.0 9.7 1.5 7.8 9.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SDA1 PF05285.12 GBG89401.1 - 1.6 8.1 22.9 1.9 7.9 22.9 1.0 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG89401.1 - 4.2 6.0 9.4 5.2 5.7 9.4 1.2 1 0 0 1 1 1 0 Presenilin Sigma70_ner PF04546.13 GBG89402.1 - 0.0059 16.5 4.2 0.0069 16.3 4.2 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF3807 PF12720.7 GBG89402.1 - 0.089 13.1 12.9 0.12 12.7 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CDC45 PF02724.14 GBG89402.1 - 0.48 8.7 15.1 0.6 8.3 15.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 GBG89402.1 - 2.3 7.5 22.4 3.5 6.9 22.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pkinase PF00069.25 GBG89403.1 - 5.5e-32 111.2 0.0 7.5e-31 107.4 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG89403.1 - 3.8e-29 101.8 0.0 3.9e-20 72.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase NHL PF01436.21 GBG89403.1 - 0.0002 21.2 0.3 0.014 15.4 0.1 2.8 2 0 0 2 2 2 1 NHL repeat MHYT PF03707.16 GBG89403.1 - 0.11 12.7 0.8 0.32 11.2 0.8 1.8 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat NICE-3 PF07406.11 GBG89403.1 - 0.55 10.2 3.3 24 4.8 1.6 2.3 2 0 0 2 2 2 0 NICE-3 protein Gaa1 PF04114.14 GBG89404.1 - 4.7e-44 151.3 0.0 8.4e-44 150.4 0.0 1.4 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Methyltransf_31 PF13847.6 GBG89405.1 - 5.1e-15 55.6 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GBG89405.1 - 1.3e-14 54.3 1.0 2.2e-14 53.6 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GBG89405.1 - 3.4e-14 52.8 0.1 6.9e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GBG89405.1 - 4.7e-11 43.2 0.3 1.5e-10 41.6 0.3 1.9 1 0 0 1 1 1 1 Methyltransferase domain Mur_ligase_M PF08245.12 GBG89405.1 - 3.1e-10 40.4 0.1 3.6e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Mur ligase middle domain Methyltransf_11 PF08241.12 GBG89405.1 - 3.2e-08 34.1 0.1 1.2e-07 32.3 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GBG89405.1 - 6.7e-08 32.4 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 GBG89405.1 - 1.5e-07 31.3 0.2 7.9e-07 28.9 0.2 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Mur_ligase_C PF02875.21 GBG89405.1 - 2.7e-07 30.8 0.0 6.6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Methyltransf_15 PF09445.10 GBG89405.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 GBG89405.1 - 6.4e-05 22.8 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 GBG89405.1 - 0.00013 22.6 0.0 0.00043 21.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GBG89405.1 - 0.00018 20.9 0.1 0.00031 20.2 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 GBG89405.1 - 0.0015 18.3 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 GBG89405.1 - 0.0021 18.0 0.2 0.0051 16.8 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GBG89405.1 - 0.0022 17.7 0.4 0.0054 16.5 0.4 1.6 1 0 0 1 1 1 1 Lysine methyltransferase N6_Mtase PF02384.16 GBG89405.1 - 0.0034 16.7 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase CMAS PF02353.20 GBG89405.1 - 0.005 16.2 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 GBG89405.1 - 0.0097 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GBG89405.1 - 0.041 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 GBG89405.1 - 0.079 12.5 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 AviRa PF11599.8 GBG89405.1 - 0.29 10.6 1.5 0.93 8.9 0.9 2.1 1 1 1 2 2 2 0 RRNA methyltransferase AviRa RT_RNaseH_2 PF17919.1 GBG89407.1 - 1.3e-34 118.2 0.0 3.9e-34 116.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89407.1 - 3.4e-29 101.2 0.0 1.1e-28 99.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89407.1 - 2.7e-16 59.4 1.3 5.4e-16 58.4 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG89407.1 - 8.4e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89407.1 - 0.005 17.4 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89407.1 - 0.029 14.9 0.0 0.09 13.4 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Med8 PF10232.9 GBG89408.1 - 0.22 11.1 7.5 0.52 9.9 7.5 1.7 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Spc7 PF08317.11 GBG89408.1 - 0.41 9.5 12.0 11 4.8 10.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Trimer_CC PF08954.11 GBG89408.1 - 0.69 9.5 0.0 0.69 9.5 0.0 4.3 3 2 2 5 5 5 0 Trimerisation motif Prefoldin_2 PF01920.20 GBG89408.1 - 1.1 9.3 13.1 1.5 8.8 3.3 3.1 3 0 0 3 3 3 0 Prefoldin subunit DUF4407 PF14362.6 GBG89408.1 - 1.5 8.1 6.1 2 7.7 5.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3386 PF11866.8 GBG89409.1 - 0.086 12.3 0.2 0.086 12.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3386) PTRF_SDPR PF15237.6 GBG89409.1 - 2.5 7.7 17.6 0.016 14.8 7.5 2.5 3 1 0 3 3 3 0 PTRF/SDPR family Fungal_TACC PF12709.7 GBG89409.1 - 3.6 8.1 8.4 0.51 10.8 2.7 2.6 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins gag-asp_proteas PF13975.6 GBG89410.1 - 6.9e-08 33.0 0.0 2.1e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89410.1 - 8.7e-07 29.5 2.0 2.3e-06 28.1 0.1 2.8 4 0 0 4 4 4 1 Aspartyl protease Asp_protease PF09668.10 GBG89410.1 - 0.00027 20.7 0.1 0.00047 19.9 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG89410.1 - 0.00047 19.9 0.0 0.00082 19.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A3 PF02160.15 GBG89410.1 - 0.14 11.6 0.3 0.58 9.6 0.0 2.0 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) Cellulose_synt PF03552.14 GBG89411.1 - 0 1153.9 1.1 0 1153.5 1.1 1.1 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.6 GBG89411.1 - 2.6e-20 72.3 7.1 5.5e-20 71.3 7.1 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 GBG89411.1 - 2.7e-12 46.3 12.4 5.4e-12 45.3 12.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Glyco_trans_2_3 PF13632.6 GBG89411.1 - 1.7e-05 24.9 1.9 1.7e-05 24.9 1.9 3.1 3 0 0 3 3 3 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG89411.1 - 3.2e-05 23.8 0.0 7.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 zf-C3HC4_3 PF13920.6 GBG89411.1 - 0.012 15.5 9.7 0.024 14.5 9.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_tranf_2_3 PF13641.6 GBG89411.1 - 0.14 12.0 0.4 0.76 9.6 0.0 2.3 3 0 0 3 3 3 0 Glycosyltransferase like family 2 zf-C3HC4 PF00097.25 GBG89411.1 - 0.18 11.7 8.2 0.37 10.7 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG89411.1 - 1.8 8.9 9.9 4.3 7.8 9.9 1.7 1 0 0 1 1 1 0 Ring finger domain DUF373 PF04123.13 GBG89411.1 - 5.8 6.2 9.3 8.9 5.7 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) 2-Hacid_dh_C PF02826.19 GBG89414.1 - 5.2e-47 159.5 0.3 2.5e-46 157.3 0.3 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GBG89414.1 - 1.9e-17 63.2 0.0 2.8e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 GBG89414.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Osmo_MPGsynth PF09488.10 GBG89414.1 - 0.071 11.8 0.1 0.1 11.2 0.1 1.1 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) RT_RNaseH_2 PF17919.1 GBG89415.1 - 4.5e-32 110.1 0.0 8e-32 109.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89415.1 - 1.3e-19 70.4 0.0 2.7e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG89415.1 - 3.7e-08 33.1 1.1 6.6e-08 32.3 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG89415.1 - 0.079 12.8 2.8 0.17 11.8 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Nop14 PF04147.12 GBG89416.1 - 0.15 10.2 5.1 0.19 9.9 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG89416.1 - 0.46 8.7 7.2 0.62 8.3 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SIR4_SID PF16991.5 GBG89416.1 - 4.2 7.4 5.2 6.4 6.8 5.2 1.2 1 0 0 1 1 1 0 Sir4 SID domain Histone PF00125.24 GBG89417.1 - 1.3e-21 77.3 0.6 1.3e-21 77.3 0.6 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PAP_fibrillin PF04755.12 GBG89418.1 - 2.2e-71 239.9 0.0 2.9e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 PAP_fibrillin DDE_Tnp_4 PF13359.6 GBG89419.1 - 6.7e-32 110.4 0.0 4.3e-31 107.7 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89419.1 - 1.2e-17 64.2 0.0 2.2e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89419.1 - 3.9e-08 33.2 0.1 0.001 18.8 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG89420.1 - 1.2e-20 73.7 0.3 1e-13 51.2 0.0 2.7 2 1 1 3 3 3 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89420.1 - 2.8e-07 30.4 0.0 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89420.1 - 0.0032 17.1 0.3 4.7 6.8 0.1 3.7 3 1 1 4 4 4 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG89420.1 - 0.0046 17.3 0.1 1 9.7 0.0 2.5 2 0 0 2 2 2 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG89421.1 - 1.7e-08 34.7 1.4 2.7e-08 34.1 0.1 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Voldacs PF03517.13 GBG89421.1 - 0.16 12.1 0.1 0.46 10.6 0.1 1.8 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Pep_deformylase PF01327.21 GBG89423.1 - 0.011 15.4 2.0 0.02 14.5 2.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase DDE_Tnp_4 PF13359.6 GBG89424.1 - 6e-32 110.5 0.1 9.3e-31 106.6 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89424.1 - 1.9e-14 53.8 0.0 3.3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89424.1 - 0.00048 19.8 2.2 1.5 8.4 0.1 3.2 3 0 0 3 3 3 2 Transposase DDE domain UcrQ PF02939.16 GBG89424.1 - 0.22 11.5 0.5 0.78 9.7 0.0 2.2 3 0 0 3 3 3 0 UcrQ family Myb_DNA-bind_4 PF13837.6 GBG89425.1 - 6.9e-08 32.8 1.1 1.1e-06 28.9 0.4 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG89428.1 - 4.5e-31 107.8 0.0 7.3e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89428.1 - 1.6e-09 37.5 0.2 4.3e-09 36.0 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCCH PF00642.24 GBG89429.1 - 2.9e-10 39.8 3.2 2.9e-10 39.8 3.2 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 GBG89429.1 - 1.8e-07 30.9 6.9 3.6e-07 29.9 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 GBG89429.1 - 7.6e-06 25.8 5.2 7.6e-06 25.8 5.2 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-C3HC4 PF00097.25 GBG89429.1 - 1e-05 25.3 11.3 2.3e-05 24.1 11.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG89429.1 - 1.7e-05 24.7 11.0 3e-05 23.9 11.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GBG89429.1 - 0.00011 22.0 10.1 0.00011 22.0 10.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 GBG89429.1 - 0.0003 20.9 4.6 0.0003 20.9 4.6 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 GBG89429.1 - 0.001 19.3 9.8 0.001 19.3 9.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-CCCH_4 PF18044.1 GBG89429.1 - 0.0018 18.0 3.3 0.0018 18.0 3.3 2.6 2 0 0 2 2 2 1 CCCH-type zinc finger zf-RING_UBOX PF13445.6 GBG89429.1 - 0.0022 18.0 9.2 0.0055 16.7 9.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GBG89429.1 - 0.013 15.3 8.6 0.025 14.4 8.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 GBG89429.1 - 0.034 14.6 1.8 0.034 14.6 1.8 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger GFO_IDH_MocA PF01408.22 GBG89429.1 - 0.14 13.0 0.0 0.21 12.4 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold zf-Nse PF11789.8 GBG89429.1 - 0.42 10.5 4.5 0.75 9.7 4.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 GBG89429.1 - 0.75 9.5 8.2 2.7 7.7 8.2 1.9 1 1 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 GBG89429.1 - 0.82 9.9 11.9 0.42 10.8 9.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING ABC_tran PF00005.27 GBG89430.1 - 4.2e-32 111.5 0.0 4.2e-32 111.5 0.0 3.4 2 1 0 2 2 1 1 ABC transporter RT_RNaseH_2 PF17919.1 GBG89430.1 - 2.9e-17 62.5 0.0 7.4e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89430.1 - 1e-07 32.2 0.0 2.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SMC_N PF02463.19 GBG89430.1 - 1.2e-07 31.4 0.0 3.5e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GBG89430.1 - 1.6e-06 28.4 0.3 2.4e-05 24.6 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG89430.1 - 2.2e-06 28.2 0.1 2.2e-06 28.2 0.1 2.7 2 1 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 GBG89430.1 - 0.00058 20.3 0.1 0.027 14.9 0.1 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GBG89430.1 - 0.0064 16.2 0.5 0.69 9.6 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein APS_kinase PF01583.20 GBG89430.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase RsgA_GTPase PF03193.16 GBG89430.1 - 0.034 14.0 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 GBG89430.1 - 0.043 13.9 0.0 0.043 13.9 0.0 3.5 2 1 1 3 3 2 0 Helicase HerA, central domain AAA_14 PF13173.6 GBG89430.1 - 0.062 13.3 0.9 0.22 11.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 GBG89430.1 - 0.084 12.9 0.2 0.56 10.2 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GBG89430.1 - 0.092 12.5 0.2 0.092 12.5 0.2 2.6 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 GBG89430.1 - 0.096 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 GBG89430.1 - 0.32 11.5 0.0 0.32 11.5 0.0 3.8 5 1 0 5 5 3 0 AAA domain AAA_33 PF13671.6 GBG89430.1 - 0.56 10.4 0.0 0.56 10.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 GBG89430.1 - 0.81 9.2 7.1 1.3 8.6 2.5 3.0 2 1 0 2 2 2 0 AAA domain RT_RNaseH_2 PF17919.1 GBG89431.1 - 2.7e-34 117.2 0.1 6.2e-34 116.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89431.1 - 3.7e-29 101.1 0.9 5.9e-29 100.5 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89431.1 - 3.7e-18 65.4 0.5 1.1e-17 63.9 0.4 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG89431.1 - 3.9e-15 56.1 0.0 1.4e-14 54.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG89431.1 - 3.3e-13 49.7 0.9 2.1e-12 47.0 0.3 2.6 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG89431.1 - 0.013 15.7 0.1 0.042 14.1 0.1 1.9 1 0 0 1 1 1 0 H2C2 zinc finger NHase_beta PF02211.15 GBG89431.1 - 0.087 12.8 0.1 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 Nitrile hydratase beta subunit RVT_1 PF00078.27 GBG89432.1 - 1.6e-33 116.1 0.1 2.9e-33 115.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89432.1 - 3.9e-20 71.7 0.0 1.6e-19 69.7 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89432.1 - 1e-09 38.6 0.1 3.8e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase LRIF1 PF15741.5 GBG89432.1 - 4.6 5.7 8.1 7 5.0 8.1 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 TP53IP5 PF15331.6 GBG89432.1 - 9.3 6.3 11.9 18 5.4 11.9 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 RT_RNaseH_2 PF17919.1 GBG89433.1 - 9.6e-53 176.4 0.0 8.3e-28 96.4 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89433.1 - 8.3e-39 132.1 0.8 2.7e-19 69.4 0.0 3.6 2 1 1 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89433.1 - 2.8e-32 112.0 0.0 5.6e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89433.1 - 2.6e-12 47.0 0.0 7.6e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain GCN5L1 PF06320.13 GBG89433.1 - 0.0043 17.2 3.0 0.0043 17.2 3.0 2.2 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) Phage_GPO PF05929.11 GBG89433.1 - 0.012 15.3 1.6 0.11 12.1 0.9 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ABC_membrane PF00664.23 GBG89434.1 - 1.5e-21 77.3 0.7 2e-21 76.8 0.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Dimer_Tnp_hAT PF05699.14 GBG89436.1 - 3.6e-08 33.1 0.1 6.9e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Hid1 PF12722.7 GBG89436.1 - 2.5 6.1 5.0 3.9 5.5 5.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 GBG89437.1 - 0.4 8.9 1.4 0.58 8.4 1.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Ferlin_C PF16165.5 GBG89437.1 - 0.43 10.5 1.1 0.83 9.6 1.1 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Beach PF02138.18 GBG89439.1 - 1e-18 67.7 0.2 2.3e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Beige/BEACH domain FUSC PF04632.12 GBG89439.1 - 0.00049 18.8 1.8 0.00069 18.3 1.8 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family Retrotrans_gag PF03732.17 GBG89439.1 - 0.0014 18.9 0.4 0.05 13.9 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein SlyX PF04102.12 GBG89439.1 - 0.059 14.0 4.0 0.069 13.8 2.7 1.9 1 1 0 1 1 1 0 SlyX DUF16 PF01519.16 GBG89439.1 - 0.098 13.2 1.0 0.27 11.7 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF2730 PF10805.8 GBG89439.1 - 0.17 12.0 0.3 0.75 9.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Beach PF02138.18 GBG89440.1 - 5.2e-23 81.8 0.0 7.1e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain Presenilin PF01080.17 GBG89441.1 - 0.037 12.8 8.0 0.061 12.1 8.0 1.3 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 GBG89442.1 - 4.4e-07 30.5 5.6 0.11 13.4 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat MPDZ_u10 PF16667.5 GBG89442.1 - 0.24 12.3 3.6 1.6 9.7 3.6 2.4 1 0 0 1 1 1 0 Unstructured region 10 on multiple PDZ protein TT_ORF2 PF02957.15 GBG89443.1 - 0.092 13.7 2.1 20 6.1 0.0 2.9 3 0 0 3 3 3 0 TT viral ORF2 zf-RanBP PF00641.18 GBG89444.1 - 4.3e-10 38.7 23.6 7.3e-06 25.2 7.0 2.8 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 GBG89444.1 - 1.7 8.7 16.0 0.46 10.6 10.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon WD40 PF00400.32 GBG89445.1 - 5.9e-61 201.0 18.8 4.8e-09 36.7 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG89445.1 - 2e-17 63.3 0.0 0.0018 18.5 0.0 6.4 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG89445.1 - 2e-06 27.9 0.0 0.0026 17.7 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 GBG89445.1 - 0.00013 20.7 0.1 0.084 11.4 0.2 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 GBG89445.1 - 0.00028 19.7 2.2 1.3 7.6 0.1 4.2 1 1 3 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GBG89445.1 - 0.0017 17.4 0.6 0.36 9.8 0.1 3.2 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4637 PF15470.6 GBG89445.1 - 0.0027 17.4 2.7 0.0051 16.6 2.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) WD40_like PF17005.5 GBG89445.1 - 0.0045 16.4 0.0 0.31 10.3 0.0 3.0 2 2 0 2 2 2 1 WD40-like domain Suf PF05843.14 GBG89445.1 - 0.022 14.7 6.0 0.046 13.7 6.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 GBG89445.1 - 0.16 11.5 19.8 0.29 10.7 19.8 1.3 1 0 0 1 1 1 0 Spt20 family PH_4 PF15404.6 GBG89445.1 - 0.17 11.7 0.9 0.3 10.8 0.9 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain SKA1 PF07160.12 GBG89445.1 - 2.6 7.8 10.2 28 4.4 0.0 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 BNR PF02012.20 GBG89446.1 - 0.067 13.2 0.1 0.27 11.4 0.1 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat DARPP-32 PF05395.12 GBG89446.1 - 0.081 13.1 1.3 0.12 12.5 1.3 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 RT_RNaseH_2 PF17919.1 GBG89449.1 - 2.4e-17 62.8 0.0 6e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89449.1 - 2.3e-15 56.8 0.0 5.7e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89449.1 - 2.8e-06 27.0 0.0 7e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG89449.1 - 0.03 14.9 0.0 0.4 11.3 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG89449.1 - 0.055 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotran_gag_2 PF14223.6 GBG89449.1 - 0.073 12.7 0.4 8.5 6.0 0.1 2.4 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Pox_Ag35 PF03286.14 GBG89449.1 - 0.14 11.9 4.1 0.26 11.1 4.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 GBG89450.1 - 0.013 13.7 26.1 0.015 13.5 26.1 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 GBG89450.1 - 1.9 8.4 14.7 2.4 8.1 14.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRAP_alpha PF03896.16 GBG89450.1 - 2.2 7.4 11.6 2.6 7.2 11.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 GBG89450.1 - 2.6 6.2 18.4 3.1 6.0 18.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 GBG89450.1 - 3.4 7.4 4.0 3.4 7.4 4.0 1.2 1 0 0 1 1 1 0 Connexin Paf1 PF03985.13 GBG89450.1 - 3.9 6.4 24.6 4.6 6.1 24.6 1.1 1 0 0 1 1 1 0 Paf1 DUF3408 PF11888.8 GBG89450.1 - 4.8 7.3 14.4 7.2 6.8 14.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) SDA1 PF05285.12 GBG89450.1 - 7.1 5.9 26.6 7.6 5.8 26.6 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 GBG89450.1 - 9.3 6.7 9.8 10 6.5 9.3 1.3 1 1 0 1 1 1 0 RNA polymerase III RPC4 DpnI PF06044.12 GBG89451.1 - 0.032 13.8 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Dam-replacing family LysM PF01476.20 GBG89452.1 - 2.3e-24 85.2 0.0 9.2e-12 44.8 0.0 2.3 2 0 0 2 2 2 2 LysM domain Sigma70_r4 PF04545.16 GBG89452.1 - 0.068 12.7 0.0 4 7.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 LysM PF01476.20 GBG89454.1 - 3.6e-22 78.2 0.0 1.1e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 LysM domain Sigma70_r4 PF04545.16 GBG89454.1 - 0.039 13.5 0.0 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.6 GBG89454.1 - 0.12 12.2 0.0 18 5.3 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Chromo PF00385.24 GBG89455.1 - 7.8e-13 48.1 0.0 1.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG89455.1 - 1e-10 41.8 0.1 3.7e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain H_PPase PF03030.16 GBG89456.1 - 9.6e-252 837.3 37.2 1.1e-251 837.1 37.2 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF659 PF04937.15 GBG89458.1 - 1.4e-13 50.9 0.0 2.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) LysM PF01476.20 GBG89459.1 - 1.7e-21 76.0 0.0 1.7e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 LysM domain RVT_1 PF00078.27 GBG89460.1 - 4.9e-10 39.3 0.0 9.1e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG89460.1 - 2.8e-05 24.6 0.0 6.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89460.1 - 0.014 16.0 0.0 0.032 14.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG89460.1 - 0.12 12.1 0.5 0.22 11.3 0.5 1.3 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG89462.1 - 8.8e-28 96.3 0.0 1.5e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89462.1 - 7.2e-25 87.3 0.0 1.5e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89462.1 - 2.6e-11 43.5 0.1 4.1e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LysM PF01476.20 GBG89463.1 - 3e-21 75.2 0.0 5e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 LysM domain Sigma70_r4 PF04545.16 GBG89463.1 - 0.066 12.7 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 LysM PF01476.20 GBG89464.1 - 4.6e-24 84.2 0.1 4e-11 42.8 0.0 2.9 3 0 0 3 3 3 2 LysM domain Sigma70_r4 PF04545.16 GBG89464.1 - 0.074 12.6 0.0 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 RT_RNaseH_2 PF17919.1 GBG89465.1 - 1e-27 96.0 0.0 1.8e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LysM PF01476.20 GBG89465.1 - 4.4e-21 74.7 0.0 3.4e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 LysM domain RT_RNaseH PF17917.1 GBG89465.1 - 9.1e-19 67.7 0.0 1.6e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AT_hook PF02178.19 GBG89466.1 - 6.5e-05 22.4 35.4 0.034 14.0 3.7 3.4 3 0 0 3 3 3 3 AT hook motif HTH_32 PF13565.6 GBG89466.1 - 2.3 8.9 7.2 9.2 7.0 0.1 3.2 3 0 0 3 3 3 0 Homeodomain-like domain SprA-related PF12118.8 GBG89467.1 - 0.004 16.3 23.3 0.0069 15.6 23.3 1.3 1 0 0 1 1 1 1 SprA-related family SID-1_RNA_chan PF13965.6 GBG89467.1 - 0.95 7.8 2.6 1.3 7.4 2.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 GBG89467.1 - 1.4 8.8 31.6 0.036 14.1 24.9 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 GBG89467.1 - 2.5 7.8 29.6 5.9 6.6 25.7 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 GBG89467.1 - 2.6 6.9 5.5 4.3 6.2 5.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.17 GBG89467.1 - 4.3 7.4 11.9 0.91 9.6 8.2 1.9 2 0 0 2 2 2 0 DDHD domain DUF913 PF06025.12 GBG89467.1 - 7.9 5.3 11.1 1.4e+02 1.2 13.3 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_pol_3_Rpc31 PF11705.8 GBG89468.1 - 1 9.6 22.1 0.9 9.7 3.2 2.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 GBG89468.1 - 5.6 6.3 17.8 7.8 5.8 17.8 1.2 1 0 0 1 1 1 0 SDA1 AT_hook PF02178.19 GBG89469.1 - 6.4e-05 22.4 52.5 0.044 13.7 3.4 5.2 5 0 0 5 5 5 4 AT hook motif SepSecS PF05889.13 GBG89470.1 - 0.16 10.6 4.4 0.12 11.1 3.3 1.5 1 1 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF659 PF04937.15 GBG89473.1 - 1.2e-07 31.7 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) JIP_LZII PF16471.5 GBG89474.1 - 0.0036 17.4 2.7 0.22 11.7 0.3 2.9 3 0 0 3 3 3 1 JNK-interacting protein leucine zipper II SlyX PF04102.12 GBG89474.1 - 0.015 15.9 0.2 0.015 15.9 0.2 3.1 4 0 0 4 4 4 0 SlyX DUF1957 PF09210.11 GBG89474.1 - 0.03 14.7 2.5 0.046 14.1 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1957) DUF4187 PF13821.6 GBG89474.1 - 0.034 13.9 1.8 0.034 13.9 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) CLZ PF16526.5 GBG89474.1 - 0.084 13.2 4.6 14 6.1 2.3 3.2 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fer4_24 PF18109.1 GBG89474.1 - 0.23 11.7 1.5 0.52 10.6 1.5 1.5 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain HALZ PF02183.18 GBG89474.1 - 3.4 8.0 5.0 61 3.9 0.6 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper ZapB PF06005.12 GBG89474.1 - 5.8 7.4 0.0 5.8 7.4 0.0 3.6 4 1 0 4 4 4 0 Cell division protein ZapB rve PF00665.26 GBG89475.1 - 3.7e-14 52.9 0.0 6.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG89475.1 - 3.3e-11 43.1 0.0 9.8e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG89475.1 - 0.0014 19.1 0.0 0.0029 18.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG89475.1 - 0.0064 16.8 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89475.1 - 0.012 16.2 0.0 0.033 14.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG89475.1 - 0.1 12.4 0.1 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease rve_3 PF13683.6 GBG89475.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG89476.1 - 0.00068 19.9 0.3 0.0094 16.2 0.1 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein Milton PF12448.8 GBG89476.1 - 0.065 13.4 2.0 0.12 12.4 2.0 1.5 1 0 0 1 1 1 0 Kinesin associated protein gag-asp_proteas PF13975.6 GBG89477.1 - 7.7e-06 26.4 0.0 1.7e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89477.1 - 0.00069 20.2 0.0 0.0018 18.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG89477.1 - 0.011 16.1 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_S7 PF00949.21 GBG89477.1 - 0.18 11.6 0.0 0.65 9.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease zf-CCHC_4 PF14392.6 GBG89478.1 - 0.043 13.6 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG89478.1 - 0.055 13.6 0.5 0.11 12.6 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle ANAPC9 PF12856.7 GBG89478.1 - 0.12 12.6 0.6 5.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 Mre11_DNA_bind PF04152.14 GBG89480.1 - 3.4 8.0 14.0 11 6.2 14.0 1.9 1 1 0 1 1 1 0 Mre11 DNA-binding presumed domain Utp14 PF04615.13 GBG89481.1 - 8.1 4.9 26.6 10 4.5 26.6 1.1 1 0 0 1 1 1 0 Utp14 protein SHE3 PF17078.5 GBG89482.1 - 0.0019 18.0 4.1 0.0019 18.0 4.1 2.4 2 1 0 2 2 2 1 SWI5-dependent HO expression protein 3 CCDC92 PF14916.6 GBG89482.1 - 0.28 11.0 4.1 2.1 8.2 0.3 2.9 2 1 0 2 2 2 0 Coiled-coil domain of unknown function BRCC36_C PF18110.1 GBG89482.1 - 0.37 11.0 1.7 1 9.5 0.0 2.5 2 1 1 3 3 3 0 BRCC36 C-terminal helical domain ZapB PF06005.12 GBG89482.1 - 0.93 10.0 17.2 0.87 10.1 0.4 4.0 2 1 1 3 3 3 0 Cell division protein ZapB LMBR1 PF04791.16 GBG89482.1 - 2.3 7.0 6.4 2.8 6.8 6.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Cnn_1N PF07989.11 GBG89482.1 - 9.4 6.5 12.0 0.96 9.7 3.4 3.0 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 RVT_1 PF00078.27 GBG89483.1 - 1.6e-13 50.7 0.0 2.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2201_N PF13203.6 GBG89483.1 - 0.082 12.5 1.5 0.098 12.2 1.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain PPP4R2 PF09184.11 GBG89483.1 - 2.1 7.9 16.0 2.7 7.5 16.0 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4746 PF15928.5 GBG89483.1 - 5.2 6.4 14.8 7.1 6.0 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 GBG89483.1 - 8.7 5.7 24.2 11 5.3 24.2 1.1 1 0 0 1 1 1 0 SDA1 SDA1 PF05285.12 GBG89484.1 - 0.034 13.6 9.5 0.041 13.3 9.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG89484.1 - 0.091 11.0 10.6 0.1 10.8 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG89484.1 - 0.11 10.7 10.0 0.11 10.7 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG89484.1 - 0.21 11.9 12.4 0.33 11.2 12.4 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SIR4_SID PF16991.5 GBG89484.1 - 2.1 8.4 5.4 3 7.9 5.4 1.2 1 0 0 1 1 1 0 Sir4 SID domain RRN3 PF05327.11 GBG89484.1 - 7.9 4.9 5.7 9 4.7 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Myb_DNA-bind_4 PF13837.6 GBG89485.1 - 1.2e-07 32.0 4.4 1.3e-07 31.9 2.8 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG89485.1 - 0.0013 19.0 2.7 0.032 14.6 0.4 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG89485.1 - 0.0035 17.5 0.6 0.011 16.0 0.6 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG89486.1 - 1.5e-16 60.5 0.0 2.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89486.1 - 3.3e-06 26.8 0.0 5.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein RT_RNaseH PF17917.1 GBG89487.1 - 7.4e-29 100.1 0.4 1.9e-27 95.6 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89487.1 - 1.5e-22 79.5 0.0 2.6e-21 75.5 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89487.1 - 4.1e-19 68.5 0.3 9e-19 67.3 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89487.1 - 4e-17 62.5 0.0 1.4e-16 60.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89487.1 - 0.0012 19.0 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Ssu72 PF04722.13 GBG89487.1 - 0.09 12.3 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 Ssu72-like protein Phage_GPO PF05929.11 GBG89487.1 - 0.14 11.8 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Asp_protease_2 PF13650.6 GBG89488.1 - 0.033 14.8 0.0 0.11 13.1 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG89488.1 - 0.13 12.8 0.1 0.37 11.4 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease FRQ PF09421.10 GBG89488.1 - 1.1 7.2 5.7 1.4 6.8 5.7 1.1 1 0 0 1 1 1 0 Frequency clock protein DUF4746 PF15928.5 GBG89488.1 - 5.9 6.2 14.4 3.3 7.0 12.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF659 PF04937.15 GBG89490.1 - 2.3e-07 30.8 0.0 3.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Med26 PF08711.11 GBG89491.1 - 1.3e-08 34.7 0.2 2.1e-08 34.1 0.2 1.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Rad51 PF08423.11 GBG89492.1 - 6.4e-94 314.0 1.7 5.7e-72 242.1 0.0 2.1 1 1 1 2 2 2 2 Rad51 RecA PF00154.21 GBG89492.1 - 2.9e-08 33.5 1.5 0.00046 19.7 0.1 2.1 1 1 1 2 2 2 2 recA bacterial DNA recombination protein HHH_5 PF14520.6 GBG89492.1 - 1.2e-06 29.0 2.8 5e-06 27.0 0.4 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix domain ATPase PF06745.13 GBG89492.1 - 1.2e-05 24.8 1.5 0.0013 18.2 0.6 2.4 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 GBG89492.1 - 0.0022 17.6 0.1 0.022 14.3 0.1 2.0 1 1 1 2 2 2 1 AAA domain HhH-GPD PF00730.25 GBG89492.1 - 0.015 15.8 0.0 0.03 14.8 0.0 1.5 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DnaB_C PF03796.15 GBG89492.1 - 0.017 14.4 0.0 0.55 9.5 0.0 2.3 1 1 0 2 2 2 0 DnaB-like helicase C terminal domain mRNA_cap_enzyme PF01331.19 GBG89493.1 - 8e-47 159.6 0.1 1.5e-45 155.4 0.1 2.5 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 GBG89493.1 - 4.8e-19 69.0 0.0 8.9e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 GBG89493.1 - 1.5e-07 31.3 0.1 3.4e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 GBG89493.1 - 0.00021 21.0 0.1 0.098 12.3 0.0 3.0 2 1 1 3 3 3 2 ATP dependent DNA ligase domain PTPRCAP PF15713.5 GBG89493.1 - 0.019 15.2 3.2 0.045 14.0 3.2 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CRAL_TRIO_2 PF13716.6 GBG89493.1 - 0.18 12.0 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain RT_RNaseH PF17917.1 GBG89494.1 - 6.1e-29 100.4 0.1 1e-28 99.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89494.1 - 1.4e-21 76.4 0.1 2.4e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG89494.1 - 1.3e-08 35.1 0.0 2.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RNA_pol_Rbc25 PF08292.12 GBG89494.1 - 0.15 12.3 8.8 0.074 13.3 2.3 2.6 3 0 0 3 3 3 0 RNA polymerase III subunit Rpc25 DUF3987 PF13148.6 GBG89494.1 - 3.8 6.4 8.9 3 6.8 7.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Presenilin PF01080.17 GBG89494.1 - 5 5.8 12.6 7.2 5.3 12.6 1.2 1 0 0 1 1 1 0 Presenilin DUF2076 PF09849.9 GBG89495.1 - 1.3 9.1 4.6 1.4 8.9 4.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ham1p_like PF01725.16 GBG89496.1 - 0.002 18.1 0.0 0.0022 18.0 0.0 1.1 1 0 0 1 1 1 1 Ham1 family DUF1275 PF06912.11 GBG89496.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Ham1p_like PF01725.16 GBG89497.1 - 3e-20 72.9 0.0 3.7e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF2681 PF10883.8 GBG89498.1 - 0.022 15.1 1.3 0.19 12.1 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4834 PF16118.5 GBG89498.1 - 0.069 14.1 0.3 0.069 14.1 0.3 5.8 5 2 0 5 5 5 0 Domain of unknown function (DUF4834) mRNA_cap_enzyme PF01331.19 GBG89499.1 - 1.1e-64 217.9 0.1 2.1e-64 217.0 0.1 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 GBG89499.1 - 1.4e-19 70.7 0.1 3.1e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 GBG89499.1 - 9.8e-10 38.4 0.0 3.3e-09 36.7 0.0 1.8 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_Y_Y PF07495.13 GBG89499.1 - 2.2e-08 33.9 0.0 0.18 11.8 0.0 5.0 5 0 0 5 5 5 2 Y_Y_Y domain DNA_ligase_A_M PF01068.21 GBG89499.1 - 3.3e-07 30.2 0.1 0.02 14.5 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Big_3_3 PF13750.6 GBG89499.1 - 0.0022 17.7 0.0 8.9 5.9 0.0 3.9 4 0 0 4 4 4 1 Bacterial Ig-like domain (group 3) Big_3_2 PF12245.8 GBG89499.1 - 0.0037 17.5 0.2 3.1 8.1 0.0 3.4 3 0 0 3 3 3 1 Bacterial Ig-like domain Y_phosphatase PF00102.27 GBG89499.1 - 0.02 14.5 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DNA_pol_phi PF04931.13 GBG89499.1 - 1.8 6.5 21.4 3.4 5.7 21.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi DUF4778 PF16008.5 GBG89500.1 - 1.9 8.5 9.3 2.3 8.2 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) BAF1_ABF1 PF04684.13 GBG89500.1 - 3.4 6.6 15.0 4 6.4 15.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RT_RNaseH PF17917.1 GBG89501.1 - 1.3e-29 102.6 0.2 3.4e-29 101.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89501.1 - 6e-24 84.0 0.0 1.4e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89501.1 - 6.7e-09 35.7 0.1 1.5e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG89501.1 - 0.096 12.3 0.1 0.096 12.3 0.1 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4790 PF16037.5 GBG89501.1 - 0.29 11.6 1.9 0.63 10.5 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4790) DUF3138 PF11336.8 GBG89503.1 - 8.2 4.9 9.1 0.23 10.0 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Asp_protease_2 PF13650.6 GBG89504.1 - 5.2e-08 33.4 0.0 1.2e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89504.1 - 2.7e-07 31.1 0.0 7.7e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG89504.1 - 3.5e-06 26.8 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89504.1 - 0.0002 21.2 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG89504.1 - 0.00033 20.9 8.0 0.00097 19.4 0.1 3.9 3 1 0 3 3 3 1 Retrotransposon gag protein SPARC_Ca_bdg PF10591.9 GBG89504.1 - 0.18 12.1 1.9 0.57 10.5 0.7 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region RT_RNaseH_2 PF17919.1 GBG89505.1 - 3.9e-27 94.2 0.0 7.6e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89505.1 - 3.7e-25 88.2 0.0 9e-25 87.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89505.1 - 6.5e-18 64.6 0.5 1.4e-17 63.5 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG89505.1 - 2.2e-12 47.0 0.1 4e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG89505.1 - 0.023 14.9 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger APG17 PF04108.12 GBG89505.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 CAP_N PF01213.19 GBG89506.1 - 0.15 11.5 2.0 0.32 10.5 2.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG89506.1 - 0.16 12.0 1.8 0.32 11.0 1.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Myb_DNA-bind_4 PF13837.6 GBG89507.1 - 5.6e-11 42.7 0.4 5.6e-11 42.7 0.4 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG89507.1 - 0.00088 19.6 0.1 0.0027 18.0 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG89507.1 - 0.04 14.2 0.2 0.085 13.1 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG89507.1 - 0.26 11.4 2.5 0.29 11.2 0.8 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain gag-asp_proteas PF13975.6 GBG89508.1 - 0.00027 21.5 0.0 0.00079 19.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89508.1 - 0.00035 21.2 0.0 0.001 19.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Pep_deformylase PF01327.21 GBG89508.1 - 0.025 14.2 2.5 0.062 12.9 2.5 1.6 1 0 0 1 1 1 0 Polypeptide deformylase RVP PF00077.20 GBG89508.1 - 0.13 12.6 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease PBP1_TM PF14812.6 GBG89509.1 - 5.3 7.5 10.1 0.078 13.4 2.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_Tnp_4 PF13359.6 GBG89510.1 - 8.6e-30 103.5 0.0 1.8e-29 102.5 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89510.1 - 3.9e-15 56.0 0.0 5.8e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89510.1 - 0.00039 20.1 0.0 0.033 13.9 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain NFACT-R_1 PF05670.13 GBG89511.1 - 4.7e-33 114.1 0.0 1.6e-32 112.4 0.0 2.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 GBG89511.1 - 1.4e-30 105.3 0.1 6.6e-30 103.2 0.1 2.3 1 0 0 1 1 1 1 NFACT protein C-terminal domain FbpA PF05833.11 GBG89511.1 - 7e-21 74.5 8.4 1.3e-16 60.4 0.0 2.5 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) zf-CCHC PF00098.23 GBG89511.1 - 4.1e-07 29.8 1.5 7.4e-07 29.0 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF5590 PF17881.1 GBG89511.1 - 0.0075 16.3 0.0 0.03 14.4 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5590) zf-CCHC_5 PF14787.6 GBG89511.1 - 0.0091 15.7 0.5 0.02 14.6 0.5 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Amidase_3 PF01520.18 GBG89511.1 - 0.019 15.1 0.9 0.048 13.8 0.9 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase zf-CCHC_3 PF13917.6 GBG89511.1 - 0.15 12.1 0.3 0.31 11.0 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG89512.1 - 6.6e-32 110.8 0.0 1.1e-31 110.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89512.1 - 4.2e-07 30.2 0.3 1.7e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG89512.1 - 1.6e-05 24.7 0.0 4.7e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Lipoprotein_22 PF17294.2 GBG89513.1 - 0.011 15.5 1.3 0.015 15.0 1.3 1.2 1 0 0 1 1 1 0 Uncharacterised lipoprotein family ALMT PF11744.8 GBG89513.1 - 8.7 5.0 6.8 11 4.7 6.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LAP1C PF05609.12 GBG89514.1 - 1.5 7.8 5.8 1.7 7.7 5.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Rrn6 PF10214.9 GBG89514.1 - 7.4 4.9 6.5 9.2 4.6 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PPR_2 PF13041.6 GBG89515.1 - 1.8e-24 85.7 6.2 7.3e-09 35.7 0.0 6.0 5 1 1 6 6 6 4 PPR repeat family PPR PF01535.20 GBG89515.1 - 1.1e-18 66.1 13.7 0.00022 21.3 0.1 7.4 7 0 0 7 7 7 4 PPR repeat PPR_3 PF13812.6 GBG89515.1 - 6.4e-14 51.8 0.0 0.00039 20.4 0.0 4.7 4 1 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG89515.1 - 5.4e-09 35.6 0.4 0.055 13.2 0.1 5.0 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 GBG89515.1 - 1.1e-07 31.4 3.9 0.00011 21.6 0.1 2.8 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP DUF3368 PF11848.8 GBG89515.1 - 0.1 12.4 0.2 23 4.9 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF3368) DUF4762 PF15959.5 GBG89517.1 - 0.0078 16.2 0.1 0.025 14.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4762) SecD-TM1 PF13721.6 GBG89517.1 - 0.88 10.1 5.2 1.2 9.7 0.7 2.8 2 1 0 2 2 2 0 SecD export protein N-terminal TM region T2SSF PF00482.23 GBG89517.1 - 1.3 8.9 3.1 3.4 7.6 3.1 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F zf-RING_2 PF13639.6 GBG89521.1 - 2.9e-11 43.5 5.4 2.9e-11 43.5 5.4 2.2 2 0 0 2 2 2 1 Ring finger domain zinc_ribbon_9 PF14369.6 GBG89521.1 - 7.5e-10 38.9 1.2 7.5e-10 38.9 1.2 2.9 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_2 PF13923.6 GBG89521.1 - 4.3e-09 36.1 5.1 4.3e-09 36.1 5.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG89521.1 - 3.6e-08 33.6 2.5 3.6e-08 33.6 2.5 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GBG89521.1 - 4.4e-08 32.7 1.4 4.4e-08 32.7 1.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 GBG89521.1 - 2.1e-06 27.5 4.2 2.1e-06 27.5 4.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG89521.1 - 1.5e-05 25.0 2.3 1.5e-05 24.9 0.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GBG89521.1 - 0.00028 20.7 8.3 0.00062 19.6 2.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GBG89521.1 - 0.00055 19.9 0.9 0.0013 18.7 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GBG89521.1 - 0.00066 19.6 10.0 0.0011 18.9 3.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain CDC45 PF02724.14 GBG89521.1 - 0.0012 17.2 8.9 0.0019 16.6 8.9 1.2 1 0 0 1 1 1 1 CDC45-like protein Zn_ribbon_17 PF17120.5 GBG89521.1 - 0.0075 15.9 3.1 0.0075 15.9 3.1 1.6 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type SDA1 PF05285.12 GBG89521.1 - 0.011 15.2 17.3 0.017 14.6 17.3 1.4 1 0 0 1 1 1 0 SDA1 HypA PF01155.19 GBG89521.1 - 0.012 15.7 4.1 0.041 13.9 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_4 PF14447.6 GBG89521.1 - 0.018 14.9 4.0 0.018 14.9 4.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 YL1 PF05764.13 GBG89521.1 - 0.021 14.9 10.4 0.063 13.4 10.4 1.8 1 0 0 1 1 1 0 YL1 nuclear protein zf-RING-like PF08746.11 GBG89521.1 - 0.031 14.6 3.5 0.031 14.6 3.5 1.7 2 0 0 2 2 1 0 RING-like domain BUD22 PF09073.10 GBG89521.1 - 0.033 13.6 13.2 0.057 12.8 13.2 1.5 1 0 0 1 1 1 0 BUD22 zf-C3H2C3 PF17122.5 GBG89521.1 - 0.056 13.5 11.8 0.58 10.3 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger CDC50 PF03381.15 GBG89521.1 - 0.24 10.9 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Rad50_zn_hook PF04423.14 GBG89521.1 - 0.33 10.8 1.9 22 5.0 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif DNA_RNApol_7kD PF03604.13 GBG89521.1 - 0.37 10.5 1.9 3.2 7.5 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 GBG89521.1 - 0.5 10.4 7.3 0.28 11.2 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon Nop14 PF04147.12 GBG89521.1 - 0.76 7.9 16.2 1 7.5 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family RINGv PF12906.7 GBG89521.1 - 0.78 9.9 2.7 2.2 8.5 2.7 1.8 1 1 0 1 1 1 0 RING-variant domain PPP4R2 PF09184.11 GBG89521.1 - 1.4 8.4 15.0 3.2 7.3 15.0 1.7 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 GBG89521.1 - 2.9 7.8 14.5 0.53 10.2 10.5 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SURF2 PF05477.11 GBG89521.1 - 6.2 6.4 5.8 44 3.7 7.3 1.7 2 0 0 2 2 1 0 Surfeit locus protein 2 (SURF2) DUF1272 PF06906.11 GBG89521.1 - 9.1 6.5 8.6 25 5.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) NOA36 PF06524.12 GBG89521.1 - 9.9 5.4 28.5 26 4.0 28.5 1.7 1 0 0 1 1 1 0 NOA36 protein ABC1 PF03109.16 GBG89523.1 - 1.8e-30 105.6 0.0 3.7e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GBG89523.1 - 0.0016 18.4 0.7 0.034 14.1 0.0 2.9 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 GBG89523.1 - 0.02 14.3 0.0 0.39 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain WaaY PF06176.11 GBG89523.1 - 0.037 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.17 GBG89524.1 - 9.8e-42 143.0 0.0 4.9e-41 140.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG89524.1 - 4.4e-33 114.8 0.0 3.3e-32 111.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Malectin_like PF12819.7 GBG89524.1 - 5.1e-20 71.9 0.0 3e-15 56.2 0.0 2.8 2 1 0 2 2 2 2 Malectin-like domain Malectin PF11721.8 GBG89524.1 - 3.3e-12 46.8 0.0 8.2e-05 22.7 0.0 2.7 2 1 0 2 2 2 2 Malectin domain LRRNT_2 PF08263.12 GBG89524.1 - 2.2e-05 24.6 0.7 6.1e-05 23.2 0.7 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 GBG89524.1 - 0.023 14.4 0.8 0.041 13.6 0.1 1.8 2 0 0 2 2 2 0 Leucine rich repeat APH PF01636.23 GBG89524.1 - 0.083 12.8 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Phosphorylase PF00343.20 GBG89525.1 - 0 1062.3 0.0 0 1062.0 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Terpene_synth_C PF03936.16 GBG89525.1 - 0.018 14.4 0.1 0.041 13.2 0.1 1.5 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain GRP PF07172.11 GBG89526.1 - 7.1 7.4 50.5 10 6.9 50.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family RVT_1 PF00078.27 GBG89528.1 - 6.8e-35 120.6 0.0 9.9e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89530.1 - 4.7e-16 59.1 0.0 8.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG89530.1 - 1.2e-13 50.9 0.0 2.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG89530.1 - 0.00064 19.4 0.0 0.0019 17.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Aha1_N PF09229.11 GBG89530.1 - 0.03 14.5 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal DUF179 PF02622.15 GBG89532.1 - 3.2e-28 98.7 0.0 6.2e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Macoilin PF09726.9 GBG89532.1 - 3.5 6.1 11.6 5.2 5.5 11.6 1.2 1 0 0 1 1 1 0 Macoilin family DUF3173 PF11372.8 GBG89533.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) DUF2933 PF11666.8 GBG89533.1 - 0.49 10.5 2.2 0.5 10.4 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2933) DUF3173 PF11372.8 GBG89534.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) DUF2933 PF11666.8 GBG89534.1 - 0.49 10.5 2.2 0.5 10.4 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2933) Histone PF00125.24 GBG89535.1 - 7.8e-25 87.7 0.5 7.8e-25 87.7 0.5 3.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG89535.1 - 0.0087 16.3 0.1 0.035 14.4 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TOM20_plant PF06552.12 GBG89536.1 - 0.036 13.8 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Bys1 PF04681.12 GBG89536.1 - 0.17 11.8 6.2 0.96 9.4 1.2 2.4 2 0 0 2 2 2 0 Blastomyces yeast-phase-specific protein RT_RNaseH_2 PF17919.1 GBG89537.1 - 6.1e-24 84.0 0.0 1.4e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89537.1 - 1.6e-22 79.8 0.0 3.4e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89537.1 - 1.1e-15 57.5 0.1 3.3e-15 55.9 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG89537.1 - 8.8e-06 25.9 4.0 0.0018 18.5 0.0 3.8 3 0 0 3 3 3 2 Retrotransposon gag protein Laminin_II PF06009.12 GBG89537.1 - 0.05 13.6 0.7 0.13 12.3 0.7 1.6 1 0 0 1 1 1 0 Laminin Domain II DUF4407 PF14362.6 GBG89537.1 - 0.98 8.7 12.0 1.5 8.1 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 GBG89537.1 - 7.1 6.9 11.5 0.46 10.7 0.4 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RNA_pol_A_bac PF01000.26 GBG89538.1 - 1.9e-34 118.4 0.0 5.3e-34 117.0 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GBG89538.1 - 5.1e-20 70.7 0.0 7.2e-20 70.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain C1_2 PF03107.16 GBG89538.1 - 0.024 14.9 1.4 0.042 14.2 1.4 1.4 1 0 0 1 1 1 0 C1 domain ANAPC4_WD40 PF12894.7 GBG89539.1 - 1.1e-14 54.4 0.6 0.0018 18.5 0.0 5.9 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG89539.1 - 3.9e-09 36.7 0.0 0.044 13.6 0.0 5.1 2 2 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 GBG89539.1 - 8.3e-08 32.8 12.9 0.01 16.7 0.0 7.2 9 0 0 9 9 9 2 WD domain, G-beta repeat PD40 PF07676.12 GBG89539.1 - 3.9e-06 26.6 3.9 0.51 10.3 0.0 5.5 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 GBG89539.1 - 0.0079 15.9 2.0 14 5.5 0.0 5.2 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature DPPIV_N PF00930.21 GBG89539.1 - 0.12 11.1 0.4 24 3.6 0.0 3.9 2 2 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9_N PF02897.15 GBG89539.1 - 0.13 11.1 0.1 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain HSF_DNA-bind PF00447.17 GBG89539.1 - 0.14 12.7 0.3 7.6 7.2 0.0 3.8 4 0 0 4 4 4 0 HSF-type DNA-binding TFIIIC_delta PF12657.7 GBG89539.1 - 0.55 10.1 4.9 10 6.0 0.5 4.2 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Goodbye PF17109.5 GBG89541.1 - 0.074 13.5 0.7 3.5 8.1 0.1 2.7 1 1 2 3 3 3 0 fungal STAND N-terminal Goodbye domain FERM_f0 PF16511.5 GBG89541.1 - 0.82 10.0 11.3 15 5.9 0.2 4.2 1 1 2 3 3 3 0 N-terminal or F0 domain of Talin-head FERM MORN_2 PF07661.13 GBG89542.1 - 0.086 13.1 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 MORN repeat variant Kelch_3 PF13415.6 GBG89543.1 - 1.1e-33 114.9 8.0 2.9e-12 46.5 0.1 7.2 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_4 PF13418.6 GBG89543.1 - 1e-32 111.8 10.4 1.2e-08 34.8 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 GBG89543.1 - 1.7e-32 110.7 3.5 1.2e-09 37.6 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 GBG89543.1 - 1.7e-30 104.3 3.2 1.1e-05 25.5 0.0 6.6 4 2 2 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GBG89543.1 - 8.4e-28 95.9 5.7 7.3e-07 29.0 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 GBG89543.1 - 7.2e-26 89.1 1.1 1.4e-08 34.3 0.0 6.6 7 0 0 7 7 7 5 Kelch motif ACBP PF00887.19 GBG89543.1 - 3.4e-18 65.6 0.1 1.7e-17 63.4 0.1 2.1 2 0 0 2 2 2 1 Acyl CoA binding protein Rootletin PF15035.6 GBG89543.1 - 0.0076 16.3 6.3 0.013 15.6 6.3 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion MscS_porin PF12795.7 GBG89543.1 - 0.0077 15.8 22.0 0.028 13.9 22.0 1.9 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF3123 PF11321.8 GBG89543.1 - 0.87 10.3 6.5 0.12 13.1 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) TIC20 PF16166.5 GBG89544.1 - 3.9e-31 108.2 5.6 5.3e-31 107.8 5.6 1.1 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like DUF3949 PF13133.6 GBG89546.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) rve PF00665.26 GBG89547.1 - 1.3e-12 47.9 0.0 3.5e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG89547.1 - 7.2e-11 41.8 0.0 1.8e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 GBG89547.1 - 0.0099 16.5 0.0 0.02 15.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease SAP PF02037.27 GBG89548.1 - 2.7e-09 36.6 0.4 5.2e-09 35.7 0.4 1.4 1 0 0 1 1 1 1 SAP domain Spt20 PF12090.8 GBG89548.1 - 0.04 13.5 6.8 0.052 13.1 6.8 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 GBG89548.1 - 0.28 10.0 16.7 0.59 8.9 3.5 2.1 2 0 0 2 2 2 0 Androgen receptor TFIIA PF03153.13 GBG89548.1 - 2.4 8.1 12.3 3.2 7.6 12.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.13 GBG89548.1 - 2.6 6.3 8.3 4.3 5.6 8.3 1.3 1 0 0 1 1 1 0 Menin SAP PF02037.27 GBG89549.1 - 4.3e-22 77.4 3.3 4.3e-11 42.3 0.2 2.3 2 0 0 2 2 2 2 SAP domain HeH PF12949.7 GBG89549.1 - 0.00026 20.6 0.3 0.76 9.5 0.2 2.4 2 0 0 2 2 2 2 HeH/LEM domain PTS_IIB PF02302.17 GBG89549.1 - 0.0059 17.3 2.8 0.12 13.1 0.1 2.4 2 1 0 2 2 2 1 PTS system, Lactose/Cellobiose specific IIB subunit Spt20 PF12090.8 GBG89549.1 - 0.0069 16.0 3.7 0.0083 15.8 3.7 1.2 1 0 0 1 1 1 1 Spt20 family Androgen_recep PF02166.16 GBG89549.1 - 0.18 10.6 16.1 0.37 9.6 2.9 2.1 2 0 0 2 2 2 0 Androgen receptor DUF3645 PF12359.8 GBG89550.1 - 0.00017 20.9 6.2 10 5.6 0.1 4.1 4 0 0 4 4 4 4 Protein of unknown function (DUF3645) RT_RNaseH_2 PF17919.1 GBG89551.1 - 2.2e-33 114.3 0.1 4.1e-33 113.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89551.1 - 2.7e-30 104.7 0.1 5.9e-30 103.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89551.1 - 1.4e-17 64.0 0.0 2.5e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5095 PF17016.5 GBG89551.1 - 0.23 11.1 0.3 0.51 10.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) RT_RNaseH PF17917.1 GBG89552.1 - 7.7e-29 100.1 0.0 2.1e-28 98.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89552.1 - 1e-28 99.3 0.0 2.3e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PARP_reg PF02877.14 GBG89552.1 - 5.3e-19 68.7 0.2 1.8e-18 67.0 0.2 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Integrase_H2C2 PF17921.1 GBG89552.1 - 4.1e-15 55.6 0.1 1e-14 54.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG89552.1 - 0.00034 20.2 0.3 0.00065 19.3 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WGR PF05406.15 GBG89552.1 - 0.034 14.2 1.7 0.082 13.0 0.0 2.5 2 0 0 2 2 2 0 WGR domain Adaptin_binding PF10199.9 GBG89552.1 - 0.073 13.7 0.3 0.073 13.7 0.3 3.6 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 TMEM51 PF15345.6 GBG89552.1 - 9.9 5.9 11.5 0.33 10.8 0.5 2.7 2 0 0 2 2 2 0 Transmembrane protein 51 RT_RNaseH_2 PF17919.1 GBG89553.1 - 7.8e-34 115.7 0.0 1.7e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89553.1 - 5.3e-29 100.6 0.1 1.6e-28 99.0 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89553.1 - 1.4e-27 96.6 0.0 2.7e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89553.1 - 1.3e-09 38.3 0.0 5.5e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG89553.1 - 8.5e-07 28.8 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG89553.1 - 1.1e-06 28.6 0.4 3.7e-06 26.9 0.4 1.9 1 1 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG89553.1 - 0.014 15.9 0.0 0.034 14.7 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89553.1 - 0.025 15.2 0.0 0.059 14.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG89553.1 - 0.033 14.5 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Snapin_Pallidin PF14712.6 GBG89553.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.8 2 0 0 2 2 2 0 Snapin/Pallidin RT_RNaseH_2 PF17919.1 GBG89554.1 - 5.9e-34 116.1 0.0 1.3e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89554.1 - 3.8e-29 101.1 0.1 1.2e-28 99.4 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89554.1 - 1e-27 97.1 0.0 2e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG89554.1 - 6.5e-07 29.2 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG89554.1 - 0.011 16.2 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89554.1 - 0.019 15.6 0.0 0.045 14.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG89554.1 - 0.025 14.9 0.0 0.09 13.1 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein Snapin_Pallidin PF14712.6 GBG89554.1 - 2.2 8.8 9.1 0.2 12.1 0.3 2.8 1 1 0 2 2 2 0 Snapin/Pallidin Retrotrans_gag PF03732.17 GBG89555.1 - 0.00053 20.2 0.0 0.00053 20.2 0.0 3.7 4 1 1 5 5 5 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG89555.1 - 0.027 14.3 2.5 0.096 12.5 2.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) FAM76 PF16046.5 GBG89555.1 - 0.061 12.7 9.6 0.14 11.5 9.6 1.6 1 0 0 1 1 1 0 FAM76 protein PspB PF06667.12 GBG89555.1 - 1.6 8.9 8.2 14 5.8 0.2 2.9 3 0 0 3 3 3 0 Phage shock protein B DUF4666 PF15697.5 GBG89555.1 - 3.5 8.3 5.9 1.9 9.2 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) eIF3_subunit PF08597.10 GBG89555.1 - 7 6.5 14.1 14 5.5 14.1 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PC-Esterase PF13839.6 GBG89556.1 - 0.022 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Filamin PF00630.19 GBG89556.1 - 0.066 14.0 0.1 1 10.2 0.0 2.6 2 1 1 3 3 3 0 Filamin/ABP280 repeat ANAPC1 PF12859.7 GBG89556.1 - 0.59 10.7 7.3 1.1 9.8 7.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Lentiviral_Tat PF02998.14 GBG89556.1 - 0.73 9.9 2.7 0.38 10.8 0.1 1.8 2 0 0 2 2 2 0 Lentiviral Tat protein Miga PF10265.9 GBG89556.1 - 2.8 6.8 4.9 4.2 6.2 4.9 1.1 1 0 0 1 1 1 0 Mitoguardin SDA1 PF05285.12 GBG89556.1 - 6.5 6.1 19.9 0.051 13.0 11.0 1.7 2 0 0 2 2 2 0 SDA1 tRNA-synt_1e PF01406.19 GBG89557.1 - 2.7e-125 417.7 0.0 3.5e-125 417.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GBG89557.1 - 6.2e-11 41.7 0.1 0.00018 20.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 GBG89557.1 - 5.6e-05 22.2 0.1 0.00027 20.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 GBG89557.1 - 0.0019 16.5 0.0 0.0071 14.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) T3SS_needle_F PF09392.10 GBG89557.1 - 0.3 11.3 2.3 24 5.2 1.0 2.4 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DHC_N1 PF08385.12 GBG89558.1 - 7e-18 64.6 0.1 1e-17 64.0 0.1 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 GP40 PF11025.8 GBG89559.1 - 0.077 12.7 11.9 3 7.6 0.8 3.1 2 1 0 3 3 3 0 Glycoprotein GP40 of Cryptosporidium DHC_N1 PF08385.12 GBG89561.1 - 2.2e-67 228.0 3.4 2.2e-67 228.0 3.4 2.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 RVT_1 PF00078.27 GBG89561.1 - 5.7e-28 97.9 0.1 1.2e-27 96.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89561.1 - 8.3e-19 67.5 0.0 2.4e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89561.1 - 1.7e-10 41.1 0.1 8.8e-09 35.6 0.0 3.0 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase V_ATPase_I PF01496.19 GBG89561.1 - 0.00078 17.5 2.8 0.00078 17.5 2.8 2.0 2 1 0 2 2 2 1 V-type ATPase 116kDa subunit family Retrotrans_gag PF03732.17 GBG89561.1 - 0.00082 19.6 12.1 0.011 16.0 0.0 5.8 5 1 0 5 5 5 1 Retrotransposon gag protein PI3Ka PF00613.20 GBG89561.1 - 0.15 11.4 2.2 1.5 8.2 0.1 2.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) NPV_P10 PF05531.12 GBG89561.1 - 0.25 11.8 4.2 14 6.2 0.2 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DHC_N2 PF08393.13 GBG89562.1 - 1e-73 248.8 5.8 1e-73 248.8 5.8 2.3 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Pan3_PK PF18101.1 GBG89562.1 - 0.041 13.9 0.6 0.32 11.0 0.1 2.3 2 0 0 2 2 2 0 Pan3 Pseudokinase domain Spectrin PF00435.21 GBG89562.1 - 0.3 11.6 0.0 0.3 11.6 0.0 4.3 6 0 0 6 6 6 0 Spectrin repeat CooT PF10133.9 GBG89564.1 - 0.043 14.1 0.0 5.3 7.4 0.0 2.3 2 0 0 2 2 2 0 CO dehydrogenase accessory protein CooT GAS PF13851.6 GBG89564.1 - 0.073 12.4 6.3 0.12 11.7 0.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding betaPIX_CC PF16523.5 GBG89564.1 - 0.1 12.4 1.6 0.41 10.5 0.1 2.4 2 1 0 2 2 2 0 betaPIX coiled coil DUF5564 PF17719.1 GBG89564.1 - 0.91 9.7 4.3 2 8.6 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5564) YabA PF06156.13 GBG89564.1 - 1 10.0 4.5 2.2 9.0 0.2 2.6 3 0 0 3 3 3 0 Initiation control protein YabA CENP-H PF05837.12 GBG89564.1 - 1.5 9.3 6.5 3 8.3 0.3 2.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Jnk-SapK_ap_N PF09744.9 GBG89564.1 - 3.2 7.9 10.3 0.67 10.2 5.8 2.1 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 NBP1 PF08537.10 GBG89565.1 - 0.013 14.9 0.7 0.013 14.9 0.7 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 rve PF00665.26 GBG89567.1 - 3.5e-06 27.2 0.0 5.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain SDA1 PF05285.12 GBG89567.1 - 0.011 15.2 17.8 0.014 14.9 17.8 1.1 1 0 0 1 1 1 0 SDA1 Plasmid_stab_B PF10784.9 GBG89567.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Plasmid stability protein CDC45 PF02724.14 GBG89567.1 - 0.029 12.7 12.3 0.035 12.4 12.3 1.0 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.11 GBG89567.1 - 0.042 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) BUD22 PF09073.10 GBG89567.1 - 0.15 11.4 19.0 0.2 11.0 19.0 1.1 1 0 0 1 1 1 0 BUD22 DUF4820 PF16091.5 GBG89567.1 - 0.18 11.1 2.3 0.26 10.6 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RNA_pol_Rpc4 PF05132.14 GBG89567.1 - 0.42 11.0 2.7 0.78 10.2 2.7 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 GBG89567.1 - 0.74 9.6 10.9 1.1 9.0 10.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 GBG89567.1 - 0.8 7.8 22.3 1 7.5 22.3 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GBG89567.1 - 1.3 7.7 7.9 1.7 7.3 7.9 1.1 1 0 0 1 1 1 0 Presenilin RXT2_N PF08595.11 GBG89567.1 - 3.3 7.7 11.7 7 6.7 11.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal SAPS PF04499.15 GBG89567.1 - 4.9 5.8 6.1 6.2 5.5 6.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4746 PF15928.5 GBG89567.1 - 9.7 5.5 20.8 14 5.0 20.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Mito_carr PF00153.27 GBG89568.1 - 1.2e-41 140.5 5.6 7.7e-21 73.8 0.1 3.4 1 1 2 3 3 3 3 Mitochondrial carrier protein Harakiri PF15196.6 GBG89568.1 - 0.1 13.0 0.7 0.81 10.2 0.0 2.5 2 0 0 2 2 2 0 Activator of apoptosis harakiri Oleosin PF01277.17 GBG89569.1 - 7.6e-13 48.2 25.1 9e-12 44.8 8.8 2.4 2 0 0 2 2 2 2 Oleosin DUF2371 PF10177.9 GBG89569.1 - 0.31 11.2 1.4 0.61 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Oleosin PF01277.17 GBG89570.1 - 3.2e-10 39.8 32.2 6.2e-09 35.6 12.9 3.4 3 1 1 4 4 4 3 Oleosin DUF5345 PF17280.2 GBG89570.1 - 0.06 13.3 0.3 0.06 13.3 0.3 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5345) DUF3318 PF11780.8 GBG89570.1 - 0.52 10.3 3.5 0.64 10.0 2.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3318) RVT_1 PF00078.27 GBG89571.1 - 2.5e-10 40.2 0.0 4.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG89573.1 - 0.00012 22.0 3.8 0.00012 22.0 3.8 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG89573.1 - 0.0054 16.5 3.3 0.012 15.4 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle hDGE_amylase PF14701.6 GBG89573.1 - 0.2 10.7 7.2 0.27 10.3 7.2 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain SOBP PF15279.6 GBG89573.1 - 0.61 10.6 8.9 0.97 10.0 8.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein ArAE_2_N PF10337.9 GBG89573.1 - 4.4 6.2 4.1 6.1 5.8 4.1 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF4192 PF13830.6 GBG89573.1 - 5 7.1 7.8 8.7 6.3 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) FDF PF09532.10 GBG89573.1 - 8.3 7.3 16.5 1.9 9.4 6.9 2.7 2 0 0 2 2 2 0 FDF domain Pkinase PF00069.25 GBG89574.1 - 1.4e-76 257.4 0.0 1.9e-76 257.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG89574.1 - 8e-32 110.5 0.0 1.1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GBG89574.1 - 0.0019 17.3 0.1 0.0041 16.1 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GBG89574.1 - 0.025 13.9 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 GBG89574.1 - 0.078 12.0 0.8 0.14 11.2 0.8 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 CDC45 PF02724.14 GBG89574.1 - 0.1 10.8 7.7 0.14 10.4 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 GBG89574.1 - 0.78 8.5 6.2 1.1 8.0 6.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RT_RNaseH_2 PF17919.1 GBG89576.1 - 2e-32 111.2 0.0 3.6e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89576.1 - 7.4e-31 106.6 0.0 1.3e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89576.1 - 0.0064 16.0 0.0 0.0096 15.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF229 PF02995.17 GBG89577.1 - 3.1e-40 138.2 0.1 2.9e-39 135.0 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 GBG89577.1 - 1.7e-07 30.9 1.3 6e-06 25.9 1.3 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 GBG89577.1 - 0.00059 19.5 2.3 0.0026 17.4 1.0 2.4 1 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Spectrin_like PF18373.1 GBG89577.1 - 0.12 12.5 0.1 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 Spectrin like domain Myb_DNA-bind_4 PF13837.6 GBG89578.1 - 2.2e-11 44.0 0.8 2.2e-11 44.0 0.8 2.1 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG89578.1 - 0.0057 16.9 0.3 0.014 15.7 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 GBG89578.1 - 0.022 15.7 0.5 0.06 14.3 0.3 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG89578.1 - 0.29 11.2 1.4 0.74 9.9 1.4 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG89578.1 - 0.29 11.4 2.1 2.5 8.4 0.6 2.9 3 1 0 3 3 3 0 Myb-like DNA-binding domain DRY_EERY PF09750.9 GBG89579.1 - 1.3e-27 96.7 0.5 1.3e-27 96.7 0.5 4.1 2 1 1 3 3 3 1 Alternative splicing regulator RVT_1 PF00078.27 GBG89579.1 - 3.7e-27 95.3 0.1 5.6e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Surp PF01805.20 GBG89579.1 - 2.3e-20 72.3 0.4 2.7e-12 46.5 0.1 2.7 2 0 0 2 2 2 2 Surp module RT_RNaseH_2 PF17919.1 GBG89579.1 - 0.00032 20.7 0.0 0.00087 19.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89579.1 - 0.05 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Cellulase PF00150.18 GBG89580.1 - 2.7e-07 30.3 0.5 0.00079 18.9 0.1 2.2 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 GBG89580.1 - 0.0023 17.6 0.3 0.0038 16.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) DEK_C PF08766.11 GBG89581.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain Asp_protease_2 PF13650.6 GBG89582.1 - 4e-07 30.6 0.0 8.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89582.1 - 8.2e-07 29.5 0.0 2.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG89582.1 - 1.8e-06 27.8 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89582.1 - 0.0004 20.2 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF4407 PF14362.6 GBG89582.1 - 0.071 12.4 4.0 0.12 11.7 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG89583.1 - 3.9e-31 108.3 0.0 5.3e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89583.1 - 3.1e-11 43.2 0.0 8.2e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89583.1 - 0.0015 18.7 0.1 0.0037 17.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase GIY-YIG PF01541.24 GBG89585.1 - 1.7e-06 28.2 0.0 6e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 GIY-YIG catalytic domain CDC48_N PF02359.18 GBG89585.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain WD40 PF00400.32 GBG89586.1 - 4.5e-11 43.1 6.5 0.092 13.6 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 GBG89586.1 - 0.073 12.1 0.0 4.7 6.1 0.0 2.7 1 1 2 3 3 3 0 Coatomer WD associated region AAA PF00004.29 GBG89589.1 - 4.1e-11 43.4 0.0 7.7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GBG89589.1 - 8.6e-06 25.8 0.1 0.0072 16.3 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_22 PF13401.6 GBG89589.1 - 5e-05 23.6 0.1 0.0015 18.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GBG89589.1 - 5.6e-05 23.2 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GBG89589.1 - 8.2e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GBG89589.1 - 0.0001 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GBG89589.1 - 0.00016 21.9 1.5 0.0019 18.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GBG89589.1 - 0.00052 19.7 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG89589.1 - 0.011 16.2 0.3 0.06 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 GBG89589.1 - 0.016 15.7 0.0 0.076 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GBG89589.1 - 0.019 14.7 0.0 0.056 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GBG89589.1 - 0.077 13.3 0.1 0.27 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GBG89589.1 - 0.085 12.1 0.1 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_8 PF12780.7 GBG89589.1 - 0.26 10.6 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 RVT_1 PF00078.27 GBG89590.1 - 5.9e-28 97.9 0.1 9.9e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG89590.1 - 4.4e-17 61.9 0.4 1.3e-16 60.4 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG89590.1 - 4.2e-10 39.9 0.3 1.1e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89590.1 - 0.00012 22.1 0.0 0.00031 20.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG89590.1 - 0.0013 19.0 0.0 0.0043 17.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89590.1 - 0.012 15.9 0.1 0.031 14.5 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG89592.1 - 1.3e-19 70.6 0.1 2.2e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG89592.1 - 6.6e-06 26.3 0.7 2.5e-05 24.5 0.2 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein DUF1758 PF05585.12 GBG89592.1 - 0.22 11.3 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) CDC45 PF02724.14 GBG89593.1 - 0.37 9.0 3.7 0.48 8.7 3.7 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIB PF00382.19 GBG89593.1 - 6.3 6.9 7.4 55 3.9 0.1 3.6 3 1 1 4 4 4 0 Transcription factor TFIIB repeat DDE_Tnp_4 PF13359.6 GBG89594.1 - 5.5e-24 84.6 0.0 7.3e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89594.1 - 5e-10 39.3 0.0 6.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG89595.1 - 0.0027 18.1 1.5 0.0077 16.6 1.5 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Nop14 PF04147.12 GBG89596.1 - 0.0019 16.5 20.6 0.0019 16.5 20.6 2.1 2 0 0 2 2 2 2 Nop14-like family S-AdoMet_synt_C PF02773.16 GBG89597.1 - 1.4e-64 216.2 0.3 3.4e-64 215.0 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GBG89597.1 - 7.7e-48 161.7 0.0 1.3e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG89597.1 - 1.6e-42 144.2 0.2 3.6e-42 143.1 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Chitin_bind_4 PF00379.23 GBG89597.1 - 0.12 13.0 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 Insect cuticle protein DnaJ_CXXCXGXG PF00684.19 GBG89597.1 - 0.19 12.1 2.0 0.4 11.1 2.0 1.5 1 0 0 1 1 1 0 DnaJ central domain S-AdoMet_synt_C PF02773.16 GBG89599.1 - 3.9e-65 218.0 0.3 8.9e-65 216.9 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GBG89599.1 - 1.9e-48 163.6 0.0 3.4e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG89599.1 - 2.6e-42 143.5 0.1 6e-42 142.3 0.1 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Chitin_bind_4 PF00379.23 GBG89599.1 - 0.12 13.0 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 Insect cuticle protein DnaJ_CXXCXGXG PF00684.19 GBG89599.1 - 0.19 12.1 2.0 0.4 11.1 2.0 1.5 1 0 0 1 1 1 0 DnaJ central domain BUD22 PF09073.10 GBG89602.1 - 0.82 8.9 42.6 1.1 8.5 42.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG89602.1 - 3.7 5.6 47.8 5.1 5.2 47.8 1.1 1 0 0 1 1 1 0 Nop14-like family Borrelia_P83 PF05262.11 GBG89602.1 - 5.4 5.4 15.2 5.8 5.3 15.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CENP_C_N PF15622.6 GBG89603.1 - 0.23 10.9 2.0 0.17 11.3 0.2 1.5 2 0 0 2 2 2 0 Kinetochore assembly subunit CENP-C N-terminal S-AdoMet_synt_C PF02773.16 GBG89604.1 - 9.5e-65 216.8 0.2 2.1e-64 215.6 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GBG89604.1 - 6.8e-48 161.9 0.0 1.2e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG89604.1 - 1.7e-41 140.9 0.1 3.9e-41 139.7 0.1 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Chitin_bind_4 PF00379.23 GBG89604.1 - 0.14 12.7 0.0 0.32 11.6 0.0 1.7 1 0 0 1 1 1 0 Insect cuticle protein C1_1 PF00130.22 GBG89604.1 - 0.21 11.5 0.5 0.66 9.9 0.1 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) S-AdoMet_synt_C PF02773.16 GBG89605.1 - 8.8e-65 216.9 0.2 2.1e-64 215.7 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GBG89605.1 - 5.4e-48 162.2 0.0 9.5e-48 161.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG89605.1 - 2e-42 143.9 0.2 4.6e-42 142.7 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Chitin_bind_4 PF00379.23 GBG89605.1 - 0.12 13.0 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 Insect cuticle protein DnaJ_CXXCXGXG PF00684.19 GBG89605.1 - 0.16 12.4 1.8 0.33 11.3 1.8 1.5 1 0 0 1 1 1 0 DnaJ central domain S-AdoMet_synt_C PF02773.16 GBG89606.1 - 4.2e-64 214.7 0.2 9.5e-64 213.5 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GBG89606.1 - 5.9e-48 162.1 0.0 1e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG89606.1 - 3.7e-42 143.0 0.2 8.6e-42 141.8 0.2 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Chitin_bind_4 PF00379.23 GBG89606.1 - 0.12 13.0 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 Insect cuticle protein C1_1 PF00130.22 GBG89606.1 - 0.26 11.2 0.6 0.76 9.7 0.1 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DnaJ_CXXCXGXG PF00684.19 GBG89606.1 - 0.42 11.0 2.1 0.89 10.0 2.1 1.5 1 0 0 1 1 1 0 DnaJ central domain DUF630 PF04783.12 GBG89607.1 - 0.054 13.7 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF630) Phage_Gp23 PF10669.9 GBG89607.1 - 0.34 11.2 9.4 0.5 10.7 1.5 2.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) CorA PF01544.18 GBG89607.1 - 0.64 9.3 2.4 1.1 8.5 2.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CP12 PF02672.15 GBG89607.1 - 1.2 10.0 4.7 7.6 7.4 1.6 2.7 2 0 0 2 2 2 0 CP12 domain Osmo_CC PF08946.10 GBG89607.1 - 2.3 8.5 5.9 6.5 7.1 1.5 3.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil WD40_alt PF14077.6 GBG89607.1 - 2.4 8.1 6.9 0.31 10.9 1.1 2.5 2 1 1 3 3 3 0 Alternative WD40 repeat motif bZIP_Maf PF03131.17 GBG89607.1 - 6.1 7.4 12.7 0.61 10.6 0.8 3.0 3 0 0 3 3 3 0 bZIP Maf transcription factor Arylesterase PF01731.20 GBG89608.1 - 0.0087 16.2 0.0 1.8 8.8 0.1 2.5 2 0 0 2 2 2 2 Arylesterase SGL PF08450.12 GBG89608.1 - 0.15 11.7 0.0 5.9 6.4 0.0 2.3 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region ANAPC10 PF03256.16 GBG89609.1 - 4.2e-54 183.0 0.1 4.7e-54 182.8 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 GBG89609.1 - 0.0013 18.9 0.0 0.0018 18.4 0.0 1.3 1 1 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 GBG89609.1 - 0.0029 17.8 0.0 0.0032 17.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain gag-asp_proteas PF13975.6 GBG89611.1 - 0.0001 22.8 0.0 0.00055 20.4 0.1 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89611.1 - 0.0049 17.5 0.1 0.016 15.8 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG89611.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89611.1 - 0.22 11.3 1.6 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG89611.1 - 0.31 10.8 1.1 0.48 10.1 0.1 1.8 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like SGL PF08450.12 GBG89613.1 - 6.3e-17 62.0 0.0 3.5e-16 59.5 0.0 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GBG89613.1 - 0.0002 21.2 0.0 0.18 11.9 0.0 4.1 4 0 0 4 4 4 1 NHL repeat HGTP_anticodon PF03129.20 GBG89614.1 - 6.7e-14 51.8 0.0 2.7e-13 49.9 0.0 2.1 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GBG89614.1 - 1.3e-12 48.0 0.0 2.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 GBG89614.1 - 0.05 13.8 0.7 0.17 12.1 0.7 1.9 1 0 0 1 1 1 0 WHEP-TRS domain Retrotrans_gag PF03732.17 GBG89614.1 - 0.14 12.4 1.0 0.62 10.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG89615.1 - 2.4e-23 82.1 0.0 4.3e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89615.1 - 8.5e-22 77.4 0.0 1.3e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89615.1 - 1.4e-14 54.1 0.0 2.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PaaX_C PF08223.11 GBG89615.1 - 0.14 12.5 0.1 0.68 10.2 0.0 2.2 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Asp_protease_2 PF13650.6 GBG89616.1 - 1.2e-07 32.2 0.0 2.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89616.1 - 1.3e-07 32.1 0.1 4.4e-07 30.4 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG89616.1 - 0.0019 18.0 0.3 0.0062 16.3 0.3 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG89616.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease COG5 PF10392.9 GBG89616.1 - 0.9 9.7 5.6 1.3 9.2 3.2 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 CREPT PF16566.5 GBG89616.1 - 2.5 8.3 13.2 0.43 10.7 4.4 3.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Nup54 PF13874.6 GBG89616.1 - 5.3 7.1 16.1 7.1 6.7 0.1 3.5 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Laminin_II PF06009.12 GBG89616.1 - 8 6.5 11.7 7.3 6.6 3.7 3.0 2 1 1 3 3 3 0 Laminin Domain II NYN_YacP PF05991.11 GBG89617.1 - 3.1e-09 37.0 0.0 3.1e-09 37.0 0.0 2.6 3 0 0 3 3 3 1 YacP-like NYN domain DUF1564 PF07600.11 GBG89617.1 - 0.0099 15.6 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) Phage_lysozyme PF00959.19 GBG89617.1 - 0.11 12.9 0.1 30 5.1 0.0 3.2 2 0 0 2 2 2 0 Phage lysozyme Retrotrans_gag PF03732.17 GBG89617.1 - 1.3 9.4 4.8 0.35 11.2 0.1 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein PPR_2 PF13041.6 GBG89618.1 - 8.4e-27 93.1 3.3 8.6e-12 45.1 0.1 5.7 2 2 4 6 6 6 4 PPR repeat family PPR_3 PF13812.6 GBG89618.1 - 1.1e-21 76.7 0.0 2.5e-09 37.1 0.0 3.6 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.20 GBG89618.1 - 1.6e-19 68.7 4.6 4.3e-05 23.5 0.0 6.3 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.7 GBG89618.1 - 4.1e-17 61.6 2.1 0.00096 18.8 0.0 5.6 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 GBG89618.1 - 6.3e-11 42.1 0.2 5e-08 32.6 0.1 2.3 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 GBG89618.1 - 0.024 14.5 0.0 6.8 6.6 0.0 3.2 1 1 2 3 3 3 0 Mitochondrial ATPase expression DSHCT PF08148.12 GBG89619.1 - 1.3e-23 83.5 1.5 7.4e-23 81.0 0.1 2.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 GBG89619.1 - 2.3e-18 66.6 0.0 4.3e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GBG89619.1 - 3.2e-06 27.3 0.0 7.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GBG89619.1 - 0.0016 18.7 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GBG89619.1 - 0.045 14.0 0.1 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GBG89619.1 - 0.051 13.0 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 GBG89619.1 - 0.099 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DDHD PF02862.17 GBG89619.1 - 0.33 11.1 6.1 26 4.9 0.1 3.9 4 0 0 4 4 4 0 DDHD domain SDA1 PF05285.12 GBG89619.1 - 9.3 5.6 66.5 0.013 15.0 28.7 3.2 3 0 0 3 3 3 0 SDA1 Fer2 PF00111.27 GBG89620.1 - 9.3e-12 44.7 0.3 2e-11 43.7 0.3 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SIL1 PF16782.5 GBG89620.1 - 0.085 12.1 0.4 0.12 11.6 0.0 1.4 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 RAB3GAP2_N PF14655.6 GBG89621.1 - 1.2e-63 215.9 0.0 2e-45 155.8 0.0 3.2 2 1 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus RVT_1 PF00078.27 GBG89621.1 - 6e-35 120.8 0.1 9.7e-35 120.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RAB3GAP2_C PF14656.6 GBG89621.1 - 2.3e-06 26.2 6.3 5.9e-06 24.8 0.0 4.0 4 1 0 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF659 PF04937.15 GBG89622.1 - 7e-15 55.2 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PBP1_TM PF14812.6 GBG89622.1 - 1.7 9.0 5.1 5.8 7.4 5.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 GBG89622.1 - 6.4 4.8 7.6 11 4.1 7.6 1.2 1 0 0 1 1 1 0 Nop14-like family Aldose_epim PF01263.20 GBG89625.1 - 3.6e-62 210.4 0.0 4e-58 197.1 0.0 2.2 2 0 0 2 2 2 2 Aldose 1-epimerase RT_RNaseH PF17917.1 GBG89625.1 - 2.5e-26 92.0 0.0 4.2e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89625.1 - 4.3e-20 71.6 0.0 8.4e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89625.1 - 4.5e-17 61.9 0.0 1.5e-15 57.0 0.0 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG89625.1 - 0.0018 18.4 0.0 0.0044 17.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG89625.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Rhamno_transf PF11316.8 GBG89625.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase Myb_DNA-bind_4 PF13837.6 GBG89626.1 - 9.1e-09 35.6 0.4 1.8e-08 34.6 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG89626.1 - 0.12 12.7 0.2 0.23 11.8 0.2 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Sad1_UNC PF07738.13 GBG89628.1 - 3.1e-32 111.3 0.0 5.6e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 GBG89628.1 - 2.9e-06 27.4 0.0 5.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain Muskelin_N PF06588.11 GBG89628.1 - 0.00034 20.6 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus GP38 PF05268.11 GBG89629.1 - 4.5 6.8 17.9 5.4 6.6 17.9 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 zf-CCHC PF00098.23 GBG89630.1 - 0.0045 17.0 4.8 0.022 14.8 4.8 2.3 1 0 0 1 1 1 1 Zinc knuckle GIY-YIG PF01541.24 GBG89630.1 - 0.0063 16.8 0.0 0.02 15.1 0.0 2.0 1 1 0 1 1 1 1 GIY-YIG catalytic domain zf-CCHC_2 PF13696.6 GBG89630.1 - 0.76 9.7 8.5 0.19 11.6 4.9 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF4800 PF16057.5 GBG89630.1 - 5.1 6.3 7.8 9 5.5 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) TIG PF01833.24 GBG89632.1 - 2e-16 59.8 1.8 2.1e-16 59.8 0.4 1.7 2 0 0 2 2 2 1 IPT/TIG domain CRISPR_assoc PF08798.11 GBG89633.1 - 0.013 15.6 1.0 0.02 15.0 1.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein Helo_like_N PF17111.5 GBG89633.1 - 0.25 10.7 4.0 0.21 10.9 2.1 1.8 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins zf-CCHC PF00098.23 GBG89634.1 - 2.4e-06 27.4 3.5 2.4e-06 27.4 3.5 2.5 2 0 0 2 2 2 1 Zinc knuckle RVT_1 PF00078.27 GBG89634.1 - 0.0015 18.1 0.0 0.073 12.6 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_29 PF00777.18 GBG89635.1 - 3.8e-42 144.6 0.0 4.8e-22 78.6 0.0 3.4 3 0 0 3 3 3 3 Glycosyltransferase family 29 (sialyltransferase) RVT_1 PF00078.27 GBG89635.1 - 1.7e-25 89.9 0.3 6.9e-25 87.9 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89635.1 - 2.4e-24 85.3 0.1 7.2e-23 80.5 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89635.1 - 1.2e-18 67.0 0.1 3.3e-18 65.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG89635.1 - 6.7e-15 55.3 0.0 2.2e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89635.1 - 2.2e-08 34.0 0.0 5.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG89635.1 - 2.4e-07 31.0 0.0 6.9e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG89635.1 - 3.5e-07 30.8 0.0 8.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG89635.1 - 1.1e-06 28.4 3.8 1.1e-06 28.4 3.8 3.2 3 0 0 3 3 3 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG89635.1 - 1.7e-05 25.3 0.0 4.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease EGF_Tenascin PF18720.1 GBG89635.1 - 0.00021 21.3 5.5 0.0005 20.0 5.5 1.7 1 0 0 1 1 1 1 Tenascin EGF domain Tudor-knot PF11717.8 GBG89635.1 - 0.005 16.7 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG89635.1 - 0.0086 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG89635.1 - 0.0094 16.1 0.0 0.03 14.5 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG89635.1 - 0.034 14.4 0.1 0.21 11.9 0.0 2.5 2 0 0 2 2 1 0 Retrotransposon gag protein Glyco_transf_29 PF00777.18 GBG89636.1 - 4.9e-42 144.2 0.0 4.8e-22 78.6 0.0 3.4 3 0 0 3 3 3 3 Glycosyltransferase family 29 (sialyltransferase) RVT_1 PF00078.27 GBG89636.1 - 1.7e-25 89.8 0.3 6.9e-25 87.9 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89636.1 - 2.5e-24 85.2 0.1 7.3e-23 80.5 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89636.1 - 1.2e-18 67.0 0.1 3.3e-18 65.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG89636.1 - 6.9e-15 55.2 0.0 2.2e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89636.1 - 2.2e-08 33.9 0.0 5.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG89636.1 - 2.4e-07 31.0 0.0 6.9e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG89636.1 - 3.5e-07 30.8 0.0 8.6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG89636.1 - 1.1e-06 28.4 3.8 1.1e-06 28.4 3.8 3.2 3 0 0 3 3 3 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG89636.1 - 1.7e-05 25.3 0.0 4.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease EGF_Tenascin PF18720.1 GBG89636.1 - 0.00021 21.3 5.5 0.0005 20.0 5.5 1.7 1 0 0 1 1 1 1 Tenascin EGF domain Tudor-knot PF11717.8 GBG89636.1 - 0.0049 16.7 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG89636.1 - 0.0087 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG89636.1 - 0.0095 16.1 0.0 0.03 14.5 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG89636.1 - 0.035 14.4 0.1 0.22 11.8 0.0 2.4 2 0 0 2 2 1 0 Retrotransposon gag protein TRM13 PF05206.14 GBG89637.1 - 1.2e-43 149.5 69.5 1.2e-14 54.5 3.2 6.9 5 1 1 6 6 6 3 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 GBG89637.1 - 1.9e-09 37.1 3.2 5.8e-09 35.6 3.2 1.9 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 GBG89637.1 - 3.7e-06 26.7 0.9 6.8e-06 25.9 0.9 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Caldesmon PF02029.15 GBG89637.1 - 0.00068 18.5 47.8 0.00068 18.5 47.8 3.6 4 0 0 4 4 4 1 Caldesmon STI1 PF17830.1 GBG89638.1 - 4.1e-07 29.8 1.0 4.1e-07 29.8 1.0 3.5 4 1 0 4 4 4 2 STI1 domain RPN13_C PF16550.5 GBG89638.1 - 4.9e-07 29.9 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 UCH-binding domain GerD PF17898.1 GBG89638.1 - 2 8.4 7.4 16 5.5 7.4 2.3 1 1 0 1 1 1 0 Spore germination GerD central core domain zf-CCHC_2 PF13696.6 GBG89638.1 - 10 6.1 7.5 0.55 10.1 1.6 2.0 2 0 0 2 2 2 0 Zinc knuckle UPF0016 PF01169.19 GBG89639.1 - 1.3e-26 92.7 8.4 5.5e-21 74.7 5.8 2.6 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Reticulon PF02453.17 GBG89640.1 - 3.3e-18 66.1 6.3 5e-18 65.5 6.3 1.2 1 0 0 1 1 1 1 Reticulon NOA36 PF06524.12 GBG89640.1 - 9.1 5.5 11.5 17 4.6 11.5 1.3 1 0 0 1 1 1 0 NOA36 protein NYN PF01936.18 GBG89642.1 - 9.1e-09 35.9 0.0 9.5e-06 26.2 0.0 2.4 1 1 0 2 2 2 2 NYN domain zf-C2H2_4 PF13894.6 GBG89642.1 - 0.086 13.7 3.8 0.34 11.9 3.8 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GBG89642.1 - 0.14 12.7 8.7 0.039 14.4 4.4 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type rve PF00665.26 GBG89643.1 - 4.3e-16 59.2 0.0 9.7e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG89643.1 - 3.7e-13 49.3 0.5 1.3e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG89643.1 - 0.0013 19.3 0.0 0.0032 18.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG89643.1 - 0.0044 16.6 0.0 0.0098 15.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG89643.1 - 0.011 16.0 0.6 0.22 11.8 0.1 3.2 2 1 1 3 3 3 0 Retrotransposon gag protein rve_3 PF13683.6 GBG89643.1 - 0.013 15.3 0.0 0.048 13.5 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain RVP PF00077.20 GBG89643.1 - 0.017 15.4 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Toprim_N PF08275.11 GBG89644.1 - 0.001 19.1 3.2 80 3.3 0.0 6.6 3 3 2 6 6 6 0 DNA primase catalytic core, N-terminal domain Methyltransf_1N PF02870.15 GBG89644.1 - 0.029 15.2 8.0 35 5.3 0.0 6.6 5 3 4 9 9 9 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain PapC_C PF13953.6 GBG89644.1 - 0.96 9.3 49.0 3.6 7.5 0.7 11.4 2 2 15 17 17 17 0 PapC C-terminal domain RT_RNaseH_2 PF17919.1 GBG89645.1 - 1.2e-31 108.6 0.0 2.7e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89645.1 - 1.4e-27 96.0 0.1 4.1e-27 94.5 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89645.1 - 8.9e-19 67.4 0.2 2.4e-18 66.0 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89645.1 - 2e-12 47.4 0.0 4.9e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG89645.1 - 2.7e-09 36.9 0.5 5.5e-09 35.9 0.5 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 GBG89645.1 - 0.00096 19.1 1.0 0.0025 17.8 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 GBG89645.1 - 0.0031 17.7 0.1 0.0076 16.5 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG89645.1 - 0.08 13.2 0.3 0.43 10.9 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein DUF1564 PF07600.11 GBG89645.1 - 0.092 12.4 0.1 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) zf-CCHC PF00098.23 GBG89645.1 - 0.093 12.9 4.4 0.25 11.5 4.4 1.8 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG89646.1 - 1.8e-25 89.8 0.1 2.9e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG89646.1 - 2.6e-14 53.1 0.0 6.8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG89646.1 - 9e-12 45.2 0.1 3.2e-11 43.4 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89646.1 - 5e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG89646.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG89646.1 - 0.096 12.9 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF5634_N PF18672.1 GBG89647.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5634) RT_RNaseH_2 PF17919.1 GBG89648.1 - 1.2e-27 95.9 0.0 2.3e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89648.1 - 1.5e-21 76.7 0.0 3.2e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89648.1 - 8.2e-15 54.7 0.6 3.6e-14 52.6 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG89648.1 - 9.3e-10 38.7 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG89648.1 - 2.3e-09 37.1 0.0 3.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG89648.1 - 0.21 10.6 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 RT_RNaseH_2 PF17919.1 GBG89649.1 - 3e-28 97.8 0.0 5.2e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89649.1 - 8.4e-25 87.1 0.0 1.5e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89649.1 - 6.6e-10 38.9 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG89649.1 - 0.061 12.4 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Retrotrans_gag PF03732.17 GBG89651.1 - 0.0011 19.2 3.4 1.6 9.0 0.0 3.7 4 1 0 4 4 4 2 Retrotransposon gag protein EutC PF05985.11 GBG89651.1 - 0.18 11.1 4.5 0.26 10.6 4.5 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) DUF4288 PF14119.6 GBG89651.1 - 0.52 10.8 1.9 1.1 9.8 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) FUSC PF04632.12 GBG89651.1 - 1.8 7.0 10.1 2.7 6.4 10.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vir_act_alpha_C PF10400.9 GBG89651.1 - 5.4 7.8 8.6 27 5.5 1.1 2.7 1 1 1 2 2 2 0 Virulence activator alpha C-term RVT_1 PF00078.27 GBG89652.1 - 9e-29 100.6 0.1 1.2e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89652.1 - 3.3e-10 39.9 0.0 8.4e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG89654.1 - 5.8e-14 52.3 0.1 1.6e-13 50.9 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG89654.1 - 0.0012 19.1 0.8 0.0054 17.0 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF1564 PF07600.11 GBG89654.1 - 0.027 14.2 0.0 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) WD40_alt PF14077.6 GBG89655.1 - 0.091 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif FAM76 PF16046.5 GBG89655.1 - 0.13 11.6 7.6 0.23 10.8 7.6 1.3 1 0 0 1 1 1 0 FAM76 protein eIF3_subunit PF08597.10 GBG89655.1 - 0.14 12.1 9.6 0.21 11.5 9.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Retrotrans_gag PF03732.17 GBG89655.1 - 0.19 12.0 0.2 0.19 12.0 0.2 3.7 5 1 0 5 5 5 0 Retrotransposon gag protein DivIC PF04977.15 GBG89655.1 - 0.85 9.4 16.3 0.39 10.5 5.7 3.3 3 0 0 3 3 3 0 Septum formation initiator SlyX PF04102.12 GBG89657.1 - 0.051 14.2 5.8 0.086 13.5 0.2 2.6 2 0 0 2 2 2 0 SlyX Mis14 PF08641.12 GBG89657.1 - 0.17 12.2 7.0 0.26 11.6 4.0 2.4 2 0 0 2 2 2 0 Kinetochore protein Mis14 like DUF3682 PF12446.8 GBG89657.1 - 0.18 12.3 5.7 0.38 11.2 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF3584 PF12128.8 GBG89657.1 - 0.55 7.7 12.4 4.8 4.6 10.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 GBG89657.1 - 1.2 8.4 8.8 1.7 7.9 8.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) gag-asp_proteas PF13975.6 GBG89658.1 - 0.00034 21.1 0.0 0.00089 19.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89658.1 - 0.00041 20.9 0.0 0.00094 19.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG89658.1 - 0.00065 20.0 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89658.1 - 0.037 13.8 0.3 0.091 12.6 0.1 1.7 2 0 0 2 2 2 0 Aspartyl protease Rx_N PF18052.1 GBG89658.1 - 0.054 13.8 0.7 4.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Rx N-terminal domain RVT_1 PF00078.27 GBG89659.1 - 3.3e-27 95.5 0.1 4.4e-27 95.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG89659.1 - 0.078 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease His_kinase PF06580.13 GBG89659.1 - 0.31 11.4 1.0 2.9 8.3 1.0 2.3 1 1 0 1 1 1 0 Histidine kinase RT_RNaseH_2 PF17919.1 GBG89660.1 - 4.8e-31 106.8 0.0 8.4e-31 106.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89660.1 - 1e-28 99.7 0.1 1.9e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89660.1 - 1.9e-28 99.5 0.0 3.2e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG89660.1 - 0.0057 16.7 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Integrase_H2C2 PF17921.1 GBG89662.1 - 3.5e-18 65.5 0.3 7.3e-18 64.4 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG89662.1 - 1.7e-17 63.7 0.1 3e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89662.1 - 3.3e-09 37.0 0.0 8.6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG89662.1 - 8.9e-09 35.2 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89662.1 - 9.3e-08 32.6 0.1 3.2e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89662.1 - 2.1e-06 28.2 0.0 4.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG89662.1 - 0.00076 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG89662.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG89662.1 - 0.13 12.5 0.0 0.46 10.8 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG89663.1 - 2.1e-27 96.1 0.0 3.2e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89663.1 - 8.6e-26 89.9 0.0 2.3e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89663.1 - 2.2e-24 85.8 0.0 5.1e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sucrose_synth PF00862.19 GBG89664.1 - 1.1e-31 109.9 0.0 1.1e-31 109.8 0.0 1.0 1 0 0 1 1 1 1 Sucrose synthase zf-CCHC PF00098.23 GBG89665.1 - 4.4e-05 23.4 0.6 8.1e-05 22.5 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Sucrose_synth PF00862.19 GBG89666.1 - 3.1e-255 847.7 0.0 3.7e-255 847.4 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG89666.1 - 7.4e-28 97.2 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG89666.1 - 1.5e-10 41.6 0.0 3.5e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG89666.1 - 0.00032 21.0 0.0 0.00093 19.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pox_D5 PF03288.16 GBG89666.1 - 0.066 13.7 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 Poxvirus D5 protein-like LRR_9 PF14580.6 GBG89667.1 - 9.3e-10 38.3 2.2 1.8e-09 37.3 2.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 GBG89667.1 - 6.9e-09 35.4 10.5 5e-08 32.6 1.6 3.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 GBG89667.1 - 4.3e-08 33.3 13.5 3.5e-06 27.2 5.4 3.4 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG89667.1 - 0.019 15.0 2.6 3.6 7.9 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich repeat Sec34 PF04136.15 GBG89667.1 - 0.043 13.7 2.2 0.046 13.6 0.2 2.0 2 0 0 2 2 2 0 Sec34-like family Macoilin PF09726.9 GBG89667.1 - 0.88 8.1 10.1 1.1 7.8 10.1 1.1 1 0 0 1 1 1 0 Macoilin family CCDC24 PF15669.5 GBG89667.1 - 4 7.3 9.4 1.5 8.6 6.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family SSP160 PF06933.11 GBG89667.1 - 5.8 5.0 24.4 7.8 4.6 24.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ZapB PF06005.12 GBG89668.1 - 1 9.8 9.0 0.99 9.9 0.2 2.4 2 0 0 2 2 2 0 Cell division protein ZapB RT_RNaseH_2 PF17919.1 GBG89669.1 - 2.4e-24 85.3 0.0 5.9e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89669.1 - 8.1e-23 80.7 0.0 1.8e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89669.1 - 1.9e-19 69.5 0.4 7.4e-19 67.6 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG89669.1 - 6.4e-10 38.9 0.1 9.9e-10 38.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89669.1 - 2.7e-09 37.3 0.0 6.7e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89669.1 - 0.15 12.3 0.8 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 H2C2 zinc finger TFIIS_C PF01096.18 GBG89670.1 - 5.2e-16 58.2 8.4 5.2e-16 58.2 8.4 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) ADK_lid PF05191.14 GBG89670.1 - 0.13 12.3 3.1 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid SMN PF06003.12 GBG89671.1 - 0.092 12.0 0.8 0.15 11.3 0.8 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Draxin PF15550.6 GBG89671.1 - 6.2 6.6 7.3 0.67 9.8 3.1 1.4 2 0 0 2 2 2 0 Draxin Myb_DNA-bind_4 PF13837.6 GBG89672.1 - 2.1e-07 31.2 2.6 6.6e-07 29.6 1.2 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain HSP20 PF00011.21 GBG89673.1 - 1.2e-19 70.3 1.5 1.6e-19 69.9 1.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG89673.1 - 6.8e-11 41.6 0.2 1.9e-10 40.2 0.2 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 GBG89673.1 - 0.062 14.3 0.0 0.089 13.8 0.0 1.2 1 0 0 1 1 1 0 CS domain PIH1_CS PF18201.1 GBG89673.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 PIH1 CS-like domain Sporozoite_P67 PF05642.11 GBG89673.1 - 9 4.2 13.1 10 4.1 13.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HSP20 PF00011.21 GBG89674.1 - 2.2e-20 72.7 1.4 3e-20 72.3 1.4 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG89674.1 - 1.6e-11 43.6 0.3 3.4e-11 42.5 0.3 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA RsgA_GTPase PF03193.16 GBG89675.1 - 2.2e-47 161.1 0.0 4e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 GBG89675.1 - 0.00014 22.4 6.7 0.048 14.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GBG89675.1 - 0.0032 17.9 0.1 0.012 16.0 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GBG89675.1 - 0.005 16.9 0.0 0.12 12.5 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GBG89675.1 - 0.0073 16.6 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GBG89675.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GBG89675.1 - 0.033 14.7 0.1 0.033 14.7 0.1 2.1 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 GBG89675.1 - 0.046 13.4 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GBG89675.1 - 0.083 12.8 0.2 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain RecO_C PF02565.15 GBG89675.1 - 0.11 12.3 0.1 0.38 10.5 0.1 1.9 1 0 0 1 1 1 0 Recombination protein O C terminal DUF4366 PF14283.6 GBG89675.1 - 0.23 11.5 1.8 0.46 10.5 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Paf1 PF03985.13 GBG89675.1 - 1.8 7.5 14.8 4.4 6.2 14.8 1.6 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.16 GBG89675.1 - 5.2 6.2 8.2 13 4.9 8.2 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HSP20 PF00011.21 GBG89676.1 - 3.4e-22 78.5 0.2 4.9e-22 78.0 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG89676.1 - 1.8e-10 40.2 0.0 3.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF410 PF04190.13 GBG89679.1 - 1.2e-61 208.7 0.0 1.5e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) HSP20 PF00011.21 GBG89680.1 - 3.7e-17 62.3 0.4 3.7e-17 62.3 0.4 2.3 2 1 0 2 2 1 1 Hsp20/alpha crystallin family Borrelia_P83 PF05262.11 GBG89680.1 - 2.5e-06 26.3 9.7 3e-06 26.0 9.7 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein ArsA_HSP20 PF17886.1 GBG89680.1 - 1.8e-05 24.2 0.1 3.8e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Macoilin PF09726.9 GBG89680.1 - 8.3e-05 21.4 10.3 9.8e-05 21.1 10.3 1.1 1 0 0 1 1 1 1 Macoilin family SAPS PF04499.15 GBG89680.1 - 0.0075 15.1 8.1 0.011 14.6 8.1 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein PNISR PF15996.5 GBG89680.1 - 0.053 13.8 30.4 0.083 13.2 30.4 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Mem_trans PF03547.18 GBG89680.1 - 0.055 11.9 0.7 0.055 11.9 0.7 1.1 1 0 0 1 1 1 0 Membrane transport protein SDA1 PF05285.12 GBG89680.1 - 0.37 10.2 36.8 0.54 9.6 36.8 1.2 1 0 0 1 1 1 0 SDA1 FAM60A PF15396.6 GBG89680.1 - 0.67 9.9 19.3 1.2 9.1 19.3 1.4 1 0 0 1 1 1 0 Protein Family FAM60A TFIIF_alpha PF05793.12 GBG89680.1 - 0.78 8.3 40.8 1.1 7.7 40.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Asp-B-Hydro_N PF05279.11 GBG89680.1 - 2.2 8.3 28.0 3.4 7.7 28.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 GBG89680.1 - 3.9 6.1 22.7 6.1 5.5 22.7 1.3 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 GBG89680.1 - 7.9 6.3 29.2 13 5.6 29.2 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BUD22 PF09073.10 GBG89680.1 - 8.1 5.7 44.2 12 5.1 44.2 1.1 1 0 0 1 1 1 0 BUD22 ALAD PF00490.21 GBG89681.1 - 1.9e-108 362.4 1.1 9.4e-80 268.1 2.0 3.4 3 0 0 3 3 3 3 Delta-aminolevulinic acid dehydratase RVP_2 PF08284.11 GBG89681.1 - 0.015 15.1 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Sucrose_synth PF00862.19 GBG89682.1 - 5.4e-250 830.4 0.0 6.6e-250 830.1 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG89682.1 - 7.4e-28 97.2 0.0 1.3e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG89682.1 - 3.4e-10 40.5 0.0 9e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG89682.1 - 9.6e-05 22.7 0.0 0.00024 21.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG89682.1 - 0.0013 18.7 0.1 0.082 12.9 0.1 2.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Pox_D5 PF03288.16 GBG89682.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF859 PF05895.12 GBG89683.1 - 0.24 9.8 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) Tachystatin_A PF11406.8 GBG89683.1 - 0.29 11.2 4.6 0.67 10.1 4.6 1.5 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A Sporozoite_P67 PF05642.11 GBG89683.1 - 8 4.4 8.2 11 3.9 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sucrose_synth PF00862.19 GBG89684.1 - 1.2e-35 122.9 0.0 1.4e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Sucrose synthase Integrase_H2C2 PF17921.1 GBG89685.1 - 4.9e-14 52.2 0.3 1e-13 51.1 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89685.1 - 4.8e-06 26.8 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89685.1 - 0.00082 19.5 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger CDC45 PF02724.14 GBG89687.1 - 0.0075 14.6 4.4 0.014 13.7 4.4 1.4 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG89688.1 - 0.26 9.4 21.7 0.25 9.5 21.7 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG89688.1 - 0.32 10.3 15.3 0.35 10.2 15.3 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 GBG89688.1 - 0.84 9.0 21.3 0.81 9.0 21.3 1.1 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 GBG89688.1 - 1 9.3 12.0 1 9.3 12.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 GBG89688.1 - 1.1 7.5 16.0 1.1 7.4 16.0 1.0 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 GBG89688.1 - 1.1 8.8 19.4 1.1 8.8 19.4 1.1 1 0 0 1 1 1 0 PPP4R2 BSMAP PF12280.8 GBG89688.1 - 1.2 9.3 6.2 1.4 9.1 6.2 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF4820 PF16091.5 GBG89688.1 - 2 7.7 7.5 2.3 7.5 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RNA_polI_A34 PF08208.11 GBG89688.1 - 4.3 7.4 13.6 4.4 7.3 13.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Connexin PF00029.19 GBG89688.1 - 5.2 6.8 4.3 4.8 6.9 4.3 1.1 1 0 0 1 1 1 0 Connexin AIF_C PF14721.6 GBG89688.1 - 8 6.8 7.0 10 6.5 7.0 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Myb_DNA-bind_4 PF13837.6 GBG89689.1 - 3.3e-10 40.2 2.0 6.1e-08 32.9 1.3 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain LAT PF15234.6 GBG89689.1 - 0.045 13.5 0.1 0.24 11.1 0.2 1.9 2 0 0 2 2 2 0 Linker for activation of T-cells DDE_Tnp_4 PF13359.6 GBG89690.1 - 3.8e-31 107.9 0.0 2.7e-30 105.1 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89690.1 - 8.6e-15 54.9 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89690.1 - 6.6e-07 29.2 1.3 0.00023 20.9 0.0 3.0 3 0 0 3 3 3 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG89691.1 - 8.7e-10 38.9 1.2 3.2e-08 33.9 0.2 2.8 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG89691.1 - 0.21 11.7 0.8 0.63 10.2 0.8 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain SDA1 PF05285.12 GBG89692.1 - 0.069 12.6 15.8 0.077 12.4 15.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG89692.1 - 0.18 10.0 17.5 0.22 9.7 17.5 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG89692.1 - 0.28 10.5 20.0 0.37 10.1 20.0 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 GBG89692.1 - 0.48 8.5 18.8 0.62 8.1 18.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi SpoIIIAH PF12685.7 GBG89692.1 - 0.49 10.2 8.3 0.69 9.7 8.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.15 GBG89692.1 - 1.1 8.0 3.5 1.1 8.0 3.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4746 PF15928.5 GBG89692.1 - 1.5 8.2 11.5 2 7.8 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Plasmodium_Vir PF05795.11 GBG89692.1 - 1.9 7.8 4.8 2.1 7.7 4.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC45 PF02724.14 GBG89692.1 - 2.3 6.4 15.0 2.8 6.1 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 GBG89692.1 - 3.2 8.0 21.5 5.4 7.3 21.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 GBG89692.1 - 3.6 6.2 6.8 4.2 6.0 6.8 1.1 1 0 0 1 1 1 0 Presenilin Afi1 PF07792.12 GBG89692.1 - 4.4 7.8 7.5 7.3 7.1 7.5 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Lin-8 PF03353.15 GBG89692.1 - 5.8 6.4 11.6 7.7 6.0 11.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RT_RNaseH_2 PF17919.1 GBG89694.1 - 1.3e-22 79.7 0.0 2.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89694.1 - 3.2e-20 72.4 0.0 7e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89694.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EMC3_TMCO1 PF01956.16 GBG89696.1 - 2.5e-29 102.2 0.0 3e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Ribosomal_L30_N PF08079.12 GBG89697.1 - 2.4e-26 91.8 11.0 4.6e-26 90.9 11.0 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 GBG89697.1 - 1.6e-20 72.7 4.4 1.6e-20 72.7 2.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e RT_RNaseH_2 PF17919.1 GBG89699.1 - 3.1e-27 94.5 0.0 5.5e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89699.1 - 9.7e-26 90.1 0.0 1.8e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89699.1 - 5.8e-19 68.0 0.5 2.3e-18 66.1 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG89699.1 - 4.3e-09 36.6 0.0 1.5e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Bac_surface_Ag PF01103.23 GBG89700.1 - 1.9e-40 139.4 0.2 3.2e-40 138.6 0.2 1.4 1 1 0 1 1 1 1 Surface antigen POTRA PF07244.15 GBG89700.1 - 1.2e-12 48.2 0.5 0.00034 21.1 0.0 3.4 3 0 0 3 3 3 3 Surface antigen variable number repeat POTRA_2 PF08479.11 GBG89700.1 - 0.011 15.6 0.1 0.056 13.3 0.0 2.2 2 0 0 2 2 2 0 POTRA domain, ShlB-type ShlB PF03865.13 GBG89700.1 - 0.1 12.0 0.2 0.19 11.1 0.2 1.4 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB PRR20 PF15708.5 GBG89700.1 - 7 6.5 11.5 0.064 13.2 2.2 2.1 1 1 1 2 2 2 0 Proline-rich protein family 20 RAB3GAP2_N PF14655.6 GBG89701.1 - 0.0085 15.4 0.0 0.71 9.1 0.0 2.4 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus CAP_N PF01213.19 GBG89701.1 - 0.16 11.4 2.1 0.4 10.1 2.1 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-C3HC4_2 PF13923.6 GBG89702.1 - 2.1e-09 37.0 6.9 2.1e-09 37.0 6.9 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG89702.1 - 5.3e-09 35.8 2.3 5.3e-09 35.8 2.3 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GBG89702.1 - 3e-08 33.4 5.7 3e-08 33.4 5.7 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GBG89702.1 - 6.8e-08 32.7 4.5 6.8e-08 32.7 4.5 2.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG89702.1 - 1.3e-06 28.4 14.2 2e-06 27.7 8.0 3.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GBG89702.1 - 5.6e-05 23.0 6.1 5.6e-05 23.0 6.1 3.4 2 2 2 4 4 3 1 zinc-RING finger domain zf-RING_6 PF14835.6 GBG89702.1 - 0.0025 17.6 1.3 0.0025 17.6 1.3 2.6 3 1 0 3 3 3 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 GBG89702.1 - 0.0033 17.2 8.2 0.0033 17.2 8.2 3.5 2 2 2 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GBG89702.1 - 0.0052 16.9 6.6 0.0052 16.9 6.6 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GBG89702.1 - 0.041 14.2 6.9 0.041 14.2 6.9 3.6 2 2 1 3 3 3 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GBG89702.1 - 2.3 8.0 13.0 0.13 12.1 4.4 3.0 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_10 PF16685.5 GBG89702.1 - 4.1 7.6 16.1 0.085 13.0 3.8 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 gag-asp_proteas PF13975.6 GBG89704.1 - 4.8e-09 36.7 0.0 1.2e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG89704.1 - 4.2e-08 33.0 0.0 7.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG89704.1 - 9.6e-07 29.4 0.0 2.9e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG89704.1 - 0.00012 21.9 1.4 0.0002 21.2 0.4 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG89704.1 - 0.00091 19.5 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG89704.1 - 0.0029 17.6 1.1 0.0076 16.3 1.1 1.8 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG89705.1 - 7e-35 119.1 0.0 1.3e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89705.1 - 1.3e-22 80.1 0.0 2.6e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89705.1 - 1.2e-11 44.6 0.1 1.6e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG6_N PF17675.1 GBG89706.1 - 1.1 9.8 26.0 0.055 14.0 12.9 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2277 PF10041.9 GBG89706.1 - 1.8 9.0 4.4 3.4 8.1 0.4 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2277) RT_RNaseH_2 PF17919.1 GBG89707.1 - 7.8e-35 118.9 0.0 1.4e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89707.1 - 6.5e-22 77.8 0.0 1.3e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Kelch_4 PF13418.6 GBG89707.1 - 2.6e-17 62.5 0.3 6.8e-09 35.6 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GBG89707.1 - 2.7e-13 49.3 0.0 1.3e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 GBG89707.1 - 5.4e-11 42.4 0.0 3.1e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 GBG89707.1 - 1.3e-10 41.2 0.8 4.5e-08 33.2 0.1 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG89707.1 - 4.4e-09 36.1 0.0 0.00039 20.4 0.0 2.7 2 0 0 2 2 2 2 Kelch motif RVT_1 PF00078.27 GBG89707.1 - 5.5e-08 32.6 0.1 7.9e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG89707.1 - 1.8e-07 29.9 5.4 2.4e-07 29.5 5.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Kelch_2 PF07646.15 GBG89707.1 - 1.2e-06 28.2 0.0 0.00044 20.1 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Mpp10 PF04006.12 GBG89707.1 - 0.002 16.7 27.1 0.0028 16.2 27.1 1.1 1 0 0 1 1 1 1 Mpp10 protein V_ATPase_I PF01496.19 GBG89707.1 - 0.0089 14.0 4.8 0.015 13.3 4.8 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ion_trans PF00520.31 GBG89707.1 - 0.0099 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Ion transport protein MscS_TM PF12794.7 GBG89707.1 - 0.024 13.5 0.3 0.024 13.5 0.3 2.0 2 0 0 2 2 1 0 Mechanosensitive ion channel inner membrane domain 1 SID-1_RNA_chan PF13965.6 GBG89707.1 - 0.029 12.8 0.1 0.044 12.2 0.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 GBG89707.1 - 0.036 13.1 0.1 0.064 12.3 0.1 1.3 1 0 0 1 1 1 0 CLN3 protein PIG-P PF08510.12 GBG89707.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 PIG-P BSP_II PF05432.11 GBG89707.1 - 0.084 12.6 40.1 0.13 12.0 40.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 GBG89707.1 - 0.091 11.0 30.7 0.13 10.5 30.7 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 GBG89707.1 - 0.098 11.9 5.2 0.15 11.2 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 GBG89707.1 - 0.12 11.3 6.7 0.19 10.7 6.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4834 PF16118.5 GBG89707.1 - 0.25 12.3 13.7 16 6.5 13.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) RRN3 PF05327.11 GBG89707.1 - 0.27 9.8 16.0 0.38 9.2 16.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Folate_carrier PF01770.18 GBG89707.1 - 2.9 6.5 7.3 0.12 11.1 0.2 1.9 1 1 1 2 2 2 0 Reduced folate carrier HA2 PF04408.23 GBG89707.1 - 3.8 7.8 7.8 13 6.1 0.2 2.5 2 0 0 2 2 2 0 Helicase associated domain (HA2) Spore_coat_CotO PF14153.6 GBG89707.1 - 4.3 7.2 18.0 9.4 6.1 18.0 1.5 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.15 GBG89707.1 - 4.8 5.9 12.2 7.2 5.3 12.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 GBG89707.1 - 5.6 6.3 30.6 12 5.2 30.6 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SLC12 PF03522.15 GBG89707.1 - 6.2 5.7 5.8 8.8 5.2 5.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RVT_1 PF00078.27 GBG89708.1 - 1.7e-34 119.3 0.1 2.8e-34 118.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_2 PF00703.21 GBG89708.1 - 2.6e-07 31.3 0.8 0.0001 23.0 0.0 3.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 RVP_2 PF08284.11 GBG89708.1 - 1.2e-06 28.4 0.0 2.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89708.1 - 8.8e-06 26.3 0.0 2.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Ig_mannosidase PF17753.1 GBG89708.1 - 1.7e-05 24.5 0.0 4.3e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 GBG89708.1 - 3.4e-05 23.8 0.1 7.6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain gag-asp_proteas PF13975.6 GBG89708.1 - 0.0012 19.3 0.0 0.0046 17.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Mannosidase_ig PF17786.1 GBG89708.1 - 0.0014 19.2 0.2 0.011 16.4 0.0 2.6 3 0 0 3 3 2 1 Mannosidase Ig/CBM-like domain DUF1758 PF05585.12 GBG89708.1 - 0.0061 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF4392 PF14336.6 GBG89708.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) PPDFL PF15060.6 GBG89708.1 - 0.33 11.5 2.2 2.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Differentiation and proliferation regulator PHO4 PF01384.20 GBG89710.1 - 8.3e-113 376.8 14.9 1.1e-112 376.5 14.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family SKG6 PF08693.10 GBG89710.1 - 0.016 14.6 1.4 0.016 14.6 1.4 3.6 4 0 0 4 4 4 0 Transmembrane alpha-helix domain SLC3A2_N PF16028.5 GBG89710.1 - 9.2 5.9 10.9 2.3 7.8 1.3 3.5 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus RT_RNaseH_2 PF17919.1 GBG89711.1 - 2.4e-33 114.1 0.0 5e-33 113.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89711.1 - 1.6e-29 102.3 0.0 2.9e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89711.1 - 2e-27 96.1 0.0 3.6e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG89711.1 - 4.6e-16 58.7 0.6 9.8e-16 57.6 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89711.1 - 5.2e-10 39.6 0.1 6.7e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain SCAB_CC PF16712.5 GBG89714.1 - 1.3e-27 96.7 14.2 2.3e-27 95.9 14.2 1.3 1 0 0 1 1 1 1 Coiled-coil regions of plant-specific actin-binding protein SCAB-PH PF17684.1 GBG89714.1 - 2.7e-26 91.9 0.1 5.3e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 PH domain of plant-specific actin-binding protein SCAB-Ig PF16709.5 GBG89714.1 - 6.1e-23 80.7 0.0 1.1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Ig domain of plant-specific actin-binding protein SCAB-ABD PF16711.5 GBG89714.1 - 0.0008 19.2 0.3 0.0008 19.2 0.3 2.5 2 0 0 2 2 2 1 Actin-binding domain of plant-specific actin-binding protein DUF883 PF05957.13 GBG89714.1 - 7.7 7.2 8.5 3.8 8.2 3.8 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF647 PF04884.14 GBG89715.1 - 1.5e-64 217.9 0.0 2.2e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF563 PF04577.14 GBG89716.1 - 7.8e-15 55.6 0.0 4.3e-10 40.1 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF563) Peptidase_S8 PF00082.22 GBG89717.1 - 0.026 13.8 0.2 0.039 13.2 0.2 1.3 1 0 0 1 1 1 0 Subtilase family SDA1 PF05285.12 GBG89718.1 - 6.5e-05 22.5 24.0 9.1e-05 22.0 24.0 1.2 1 0 0 1 1 1 1 SDA1 Presenilin PF01080.17 GBG89718.1 - 0.0095 14.7 13.2 0.012 14.4 13.2 1.1 1 0 0 1 1 1 1 Presenilin Zip PF02535.22 GBG89718.1 - 0.62 9.2 6.7 0.83 8.8 6.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 GBG89719.1 - 0.00031 20.2 47.3 0.00037 20.0 47.3 1.0 1 0 0 1 1 1 1 BUD22 DUF4045 PF13254.6 GBG89719.1 - 0.17 11.5 25.8 0.22 11.1 25.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BAF1_ABF1 PF04684.13 GBG89719.1 - 0.28 10.2 30.9 0.35 9.9 30.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 GBG89719.1 - 0.66 8.9 18.5 0.77 8.7 18.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 GBG89719.1 - 1.1 7.3 27.1 1.3 7.1 27.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RskA PF10099.9 GBG89719.1 - 1.5 9.1 12.5 9.2 6.5 1.0 2.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF966 PF06136.13 GBG89719.1 - 3.7 7.2 23.8 4.2 7.0 23.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RVT_1 PF00078.27 GBG89720.1 - 1.3e-34 119.7 0.1 2e-34 119.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89720.1 - 3.8e-17 62.1 0.0 1.4e-16 60.3 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89720.1 - 3.8e-08 33.6 0.0 1e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG89720.1 - 1e-06 29.3 0.0 2.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG89720.1 - 1.2e-06 28.4 0.0 3.9e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG89720.1 - 0.0002 21.9 0.0 0.00092 19.7 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG89720.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF1737 PF08410.10 GBG89720.1 - 0.0034 17.2 0.0 0.0088 15.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1737) Asp_protease PF09668.10 GBG89720.1 - 0.042 13.7 0.0 0.17 11.7 0.0 2.0 2 1 0 2 2 2 0 Aspartyl protease zf-CCHC PF00098.23 GBG89721.1 - 3e-07 30.2 5.8 1e-06 28.5 5.8 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG89721.1 - 0.056 13.2 2.6 0.13 12.0 2.6 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GBG89721.1 - 0.15 11.9 2.7 0.47 10.3 2.7 1.8 1 0 0 1 1 1 0 Zinc knuckle Pico_P1A PF02226.16 GBG89722.1 - 0.11 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) RR_TM4-6 PF06459.12 GBG89723.1 - 3.6 7.3 11.8 5.1 6.8 11.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LRR_4 PF12799.7 GBG89725.1 - 6.7 7.3 10.7 15 6.2 4.4 3.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF2031 PF09592.10 GBG89726.1 - 1.9 8.0 6.7 0.97 8.9 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2031) NOA36 PF06524.12 GBG89727.1 - 0.036 13.4 0.1 0.053 12.8 0.1 1.2 1 0 0 1 1 1 0 NOA36 protein E7 PF00527.18 GBG89727.1 - 0.084 13.1 2.4 0.14 12.3 2.4 1.3 1 0 0 1 1 1 0 E7 protein, Early protein Allexi_40kDa PF05549.11 GBG89727.1 - 0.099 12.1 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Ribosomal_60s PF00428.19 GBG89727.1 - 0.27 11.8 14.2 0.056 14.0 10.7 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SGS PF05002.15 GBG89727.1 - 2.7 8.2 5.6 42 4.3 5.6 2.2 1 1 0 1 1 1 0 SGS domain RT_RNaseH_2 PF17919.1 GBG89728.1 - 1.8e-31 108.1 0.0 3.6e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89728.1 - 6.9e-30 103.4 0.0 1.6e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89728.1 - 8.7e-13 48.3 0.2 1.7e-12 47.3 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG89728.1 - 0.037 13.7 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Rhamno_transf PF11316.8 GBG89728.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase LysM PF01476.20 GBG89729.1 - 1.4e-30 105.1 0.2 3.4e-09 36.6 0.0 3.5 3 0 0 3 3 3 3 LysM domain Peptidase_M23 PF01551.22 GBG89729.1 - 1.9e-15 56.8 0.2 5.1e-15 55.5 0.2 1.8 1 0 0 1 1 1 1 Peptidase family M23 HTH_19 PF12844.7 GBG89729.1 - 0.014 15.4 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain RT_RNaseH PF17917.1 GBG89730.1 - 3.8e-23 81.8 0.0 1.8e-22 79.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89730.1 - 6.5e-21 74.2 0.0 1.8e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG89730.1 - 3.3e-13 49.9 0.0 1e-12 48.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG89730.1 - 4e-11 42.9 0.2 1.5e-10 41.1 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG89730.1 - 8.9e-09 35.2 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LMSTEN PF07988.12 GBG89730.1 - 0.013 14.9 1.2 0.07 12.6 0.4 2.6 2 0 0 2 2 2 0 LMSTEN motif Retrotrans_gag PF03732.17 GBG89730.1 - 0.064 13.5 3.4 0.092 13.0 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG89730.1 - 0.077 13.6 0.0 0.23 12.1 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Sec8_exocyst PF04048.14 GBG89730.1 - 0.12 12.2 2.5 0.45 10.4 2.5 2.0 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain gag-asp_proteas PF13975.6 GBG89730.1 - 0.14 12.8 0.0 0.4 11.3 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_5 PF14787.6 GBG89730.1 - 0.24 11.1 1.9 0.5 10.1 1.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.17 GBG89731.1 - 3.6e-07 30.3 6.1 0.012 15.8 0.1 4.2 4 0 0 4 4 4 2 Retrotransposon gag protein Peptidase_S64 PF08192.11 GBG89731.1 - 0.83 8.1 5.4 1.6 7.1 5.4 1.4 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.9 GBG89731.1 - 3.2 6.2 20.4 0.21 10.1 1.3 2.4 2 0 0 2 2 2 0 Macoilin family RT_RNaseH_2 PF17919.1 GBG89732.1 - 7.2e-31 106.2 0.0 1.4e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89732.1 - 1.7e-26 92.6 0.1 3.4e-26 91.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89732.1 - 7.6e-20 70.8 0.2 1.6e-19 69.8 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89732.1 - 7.7e-14 51.9 0.0 2.1e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89732.1 - 0.00021 21.4 0.0 0.0005 20.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF1564 PF07600.11 GBG89732.1 - 0.012 15.3 0.7 0.051 13.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Clr5 PF14420.6 GBG89732.1 - 0.065 13.5 1.3 2.5 8.4 1.0 3.1 2 0 0 2 2 2 0 Clr5 domain DUF4035 PF13227.6 GBG89733.1 - 0.045 13.5 0.3 0.12 12.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) Mem_trans PF03547.18 GBG89733.1 - 2.2 6.6 4.0 2.5 6.4 4.0 1.2 1 0 0 1 1 1 0 Membrane transport protein SAPS PF04499.15 GBG89733.1 - 6.7 5.4 10.6 7.2 5.3 10.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RT_RNaseH PF17917.1 GBG89734.1 - 4.1e-15 56.0 0.0 8.9e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89734.1 - 2.9e-10 40.0 0.0 6.8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG89734.1 - 0.0031 17.8 0.2 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF3006 PF11213.8 GBG89734.1 - 0.036 14.3 1.8 0.08 13.2 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Integrase_H2C2 PF17921.1 GBG89735.1 - 6.4e-20 71.0 0.1 1.4e-19 69.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG89735.1 - 1e-07 32.2 0.1 2.9e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89735.1 - 2.9e-07 30.4 0.0 7.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89735.1 - 8.6e-07 29.5 0.0 2.8e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG89735.1 - 8.8e-07 29.1 0.0 4.9e-06 26.7 0.0 2.4 1 1 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG89735.1 - 3.5e-05 24.3 0.0 0.00013 22.4 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.8 GBG89735.1 - 0.0002 21.2 0.0 0.00066 19.5 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.10 GBG89735.1 - 0.0019 18.0 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG89735.1 - 0.0087 16.3 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein DUF2935 PF11155.8 GBG89735.1 - 0.16 12.3 0.0 0.5 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Pkinase PF00069.25 GBG89737.1 - 4.8e-48 163.8 0.2 2.6e-30 105.7 0.0 3.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG89737.1 - 5e-43 147.3 0.0 8.2e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG89737.1 - 0.00034 20.6 0.2 0.036 14.0 0.1 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family TFIIA PF03153.13 GBG89737.1 - 0.0041 17.2 5.4 0.0041 17.2 5.4 2.7 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Flavi_DEAD PF07652.14 GBG89737.1 - 0.046 13.7 2.8 6.5 6.7 0.1 2.7 2 1 1 3 3 3 0 Flavivirus DEAD domain Herpes_env PF01673.18 GBG89737.1 - 0.91 8.4 3.2 2.1 7.2 3.2 1.5 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF913 PF06025.12 GBG89737.1 - 1.1 8.1 14.8 0.086 11.8 1.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF3228 PF11539.8 GBG89737.1 - 1.3 8.5 9.8 4.3 6.8 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) Chordopox_G3 PF06129.12 GBG89737.1 - 2.3 9.0 3.2 41 5.0 0.1 2.3 2 0 0 2 2 2 0 Chordopoxvirus G3 protein DsrH PF04077.12 GBG89738.1 - 5.1e-06 26.5 9.8 15 5.8 0.0 8.3 2 2 10 12 12 12 2 DsrH like protein Sm_like PF16243.5 GBG89738.1 - 0.028 14.5 13.0 1.5 9.1 0.1 5.5 2 2 5 7 7 7 0 Sm_like domain CstA PF02554.14 GBG89738.1 - 1.1 8.1 5.4 38 3.0 0.0 4.2 4 1 1 5 5 5 0 Carbon starvation protein CstA HTH_Tnp_1 PF01527.20 GBG89738.1 - 1.1 9.6 19.7 9.4 6.6 0.9 5.8 2 2 3 5 5 5 0 Transposase Pkinase PF00069.25 GBG89739.1 - 4.6e-44 150.7 0.0 3.3e-29 102.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG89739.1 - 2.1e-39 135.4 0.0 3.5e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG89739.1 - 0.00034 20.6 0.0 0.031 14.2 0.0 3.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family DDE_Tnp_4 PF13359.6 GBG89741.1 - 3e-22 79.0 0.0 8.1e-22 77.6 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89741.1 - 3e-07 30.3 0.0 6.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG89741.1 - 0.062 13.7 0.1 0.45 10.9 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain LapA_dom PF06305.11 GBG89743.1 - 0.016 15.0 0.2 0.032 14.1 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain T2SSM PF04612.12 GBG89743.1 - 0.077 13.0 3.8 0.078 13.0 0.5 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M MAP17 PF15807.5 GBG89743.1 - 0.21 11.8 2.2 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DDE_Tnp_4 PF13359.6 GBG89744.1 - 4.5e-27 94.7 0.0 7.7e-26 90.6 0.0 2.5 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89744.1 - 3e-13 49.9 0.0 4.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89744.1 - 8.5e-06 25.6 0.1 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain Barwin PF00967.17 GBG89744.1 - 0.073 12.9 0.3 0.61 10.0 0.1 2.3 2 0 0 2 2 2 0 Barwin family DUF4846 PF16138.5 GBG89746.1 - 0.0086 15.6 0.2 0.014 14.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (4846) DUF936 PF06075.12 GBG89746.1 - 0.075 11.9 15.0 0.075 12.0 15.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) NOA36 PF06524.12 GBG89746.1 - 0.1 11.9 17.8 0.14 11.5 17.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2722 PF10846.8 GBG89746.1 - 0.13 11.2 9.3 0.16 10.9 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Paf1 PF03985.13 GBG89746.1 - 0.15 11.0 33.0 0.19 10.7 33.0 1.1 1 0 0 1 1 1 0 Paf1 Nucleo_P87 PF07267.11 GBG89746.1 - 0.22 10.4 17.2 0.26 10.1 17.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SID-1_RNA_chan PF13965.6 GBG89746.1 - 0.26 9.7 1.7 0.25 9.7 1.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF913 PF06025.12 GBG89746.1 - 0.5 9.3 9.9 0.57 9.1 9.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BORG_CEP PF14957.6 GBG89746.1 - 0.88 10.7 9.3 1.1 10.4 9.3 1.2 1 0 0 1 1 1 0 Cdc42 effector SAGA-Tad1 PF12767.7 GBG89746.1 - 0.93 9.2 11.4 1.1 9.0 11.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AAA_11 PF13086.6 GBG89746.1 - 1 9.1 18.1 1.2 8.8 18.1 1.1 1 0 0 1 1 1 0 AAA domain DUF5427 PF10310.9 GBG89746.1 - 1.2 8.0 21.1 1.4 7.8 21.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MDM1 PF15501.6 GBG89746.1 - 1.3 8.1 36.6 1.7 7.7 36.6 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 SpoIIP PF07454.11 GBG89746.1 - 1.9 7.9 16.1 2.8 7.3 16.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 GBG89746.1 - 2.9 7.6 27.3 4.9 6.9 27.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 GBG89746.1 - 3 6.0 32.4 5.1 5.2 32.4 1.3 1 0 0 1 1 1 0 Nop14-like family Serinc PF03348.15 GBG89746.1 - 4.3 6.2 7.0 4.7 6.0 7.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SAPS PF04499.15 GBG89746.1 - 4.7 5.9 14.3 5.3 5.7 14.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 GBG89746.1 - 6 5.8 15.9 7.1 5.5 15.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 GBG89746.1 - 6.2 7.1 30.5 8.8 6.6 30.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.16 GBG89746.1 - 6.6 5.8 15.3 10 5.2 15.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM60A PF15396.6 GBG89746.1 - 7.8 6.4 19.6 10 6.1 19.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4778 PF16008.5 GBG89746.1 - 8.1 6.4 18.2 11 5.9 18.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) PPP4R2 PF09184.11 GBG89746.1 - 8.8 5.8 29.5 12 5.4 29.5 1.1 1 0 0 1 1 1 0 PPP4R2 CHAT PF12770.7 GBG89747.1 - 1.9e-41 142.4 0.7 8.2e-20 71.4 0.2 2.3 2 0 0 2 2 2 2 CHAT domain Myb_DNA-bind_4 PF13837.6 GBG89749.1 - 2e-06 28.1 0.4 1e-05 25.8 0.4 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain APG6_N PF17675.1 GBG89750.1 - 0.47 11.0 12.1 1.5 9.3 5.9 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Trans_reg_C PF00486.28 GBG89751.1 - 0.025 14.7 0.7 0.072 13.2 0.7 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal NOG1_N PF17835.1 GBG89751.1 - 0.25 11.3 5.0 0.76 9.7 5.0 1.8 1 0 0 1 1 1 0 NOG1 N-terminal helical domain DUF4559 PF15112.6 GBG89751.1 - 0.86 9.2 11.2 2.4 7.8 11.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) NifQ PF04891.12 GBG89751.1 - 3.8 7.8 5.2 3 8.2 1.7 2.5 1 1 1 2 2 2 0 NifQ DNA_pol_phi PF04931.13 GBG89753.1 - 0.013 13.6 40.6 0.015 13.5 40.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG89753.1 - 0.099 10.8 26.9 0.098 10.9 26.9 1.0 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 GBG89753.1 - 0.44 9.3 2.9 0.48 9.2 2.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 GBG89753.1 - 0.7 9.2 22.2 0.87 8.9 22.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GBG89753.1 - 2.7 6.2 24.4 3.2 5.9 24.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GBG89753.1 - 4.2 5.7 23.5 4.6 5.5 23.5 1.0 1 0 0 1 1 1 0 Mpp10 protein CNDH2_C PF16858.5 GBG89753.1 - 5.2 6.9 13.9 6 6.6 13.9 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop25 PF09805.9 GBG89753.1 - 6.7 7.2 12.8 7.8 7.0 12.8 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4637 PF15470.6 GBG89753.1 - 9.4 5.9 11.7 14 5.4 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Cpn60_TCP1 PF00118.24 GBG89754.1 - 1.1e-122 410.2 14.8 5.5e-101 338.6 8.6 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family DUF4787 PF16029.5 GBG89755.1 - 4.1e-19 68.4 1.3 4.1e-19 68.4 1.3 2.6 2 1 0 2 2 1 1 Domain of unknown function (DUF4787) Myc_N PF01056.18 GBG89755.1 - 0.0011 18.9 0.8 0.0011 18.9 0.8 1.2 1 0 0 1 1 1 1 Myc amino-terminal region UCR_hinge PF02320.16 GBG89755.1 - 0.0058 16.8 0.2 0.0058 16.8 0.2 1.9 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Pox_Ag35 PF03286.14 GBG89755.1 - 0.06 13.1 1.7 0.08 12.7 1.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3381 PF11861.8 GBG89755.1 - 0.2 11.5 8.9 0.27 11.0 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FAM176 PF14851.6 GBG89755.1 - 0.21 11.3 6.6 0.43 10.2 6.6 1.5 1 0 0 1 1 1 0 FAM176 family DUF2052 PF09747.9 GBG89755.1 - 0.24 11.5 10.5 0.33 11.1 10.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) D123 PF07065.14 GBG89755.1 - 0.29 10.2 2.6 0.4 9.8 2.6 1.1 1 0 0 1 1 1 0 D123 DUF4746 PF15928.5 GBG89755.1 - 0.47 9.8 9.0 0.6 9.5 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 GBG89755.1 - 0.61 9.0 11.3 0.79 8.7 11.3 1.1 1 0 0 1 1 1 0 Paf1 DUF4820 PF16091.5 GBG89755.1 - 1 8.7 4.0 1.4 8.2 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Med4 PF10018.9 GBG89755.1 - 1.3 8.7 9.5 1.8 8.2 9.5 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 WRNPLPNID PF15017.6 GBG89755.1 - 1.3 9.9 12.3 3.2 8.7 12.3 1.6 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Adeno_terminal PF02459.15 GBG89755.1 - 3 6.1 7.8 3.9 5.8 7.8 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein BSP_II PF05432.11 GBG89755.1 - 3.1 7.4 18.1 0.12 12.0 11.6 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.10 GBG89755.1 - 9.6 6.7 10.7 16 5.9 10.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 GBG89755.1 - 9.7 4.1 13.4 13 3.7 13.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi F-box PF00646.33 GBG89756.1 - 0.00037 20.3 3.5 0.0033 17.3 0.2 3.7 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 GBG89756.1 - 0.0012 18.7 0.3 0.0012 18.7 0.3 2.7 3 0 0 3 3 3 1 F-box-like X PF00739.19 GBG89756.1 - 0.09 12.9 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 Trans-activation protein X Pentapeptide PF00805.22 GBG89756.1 - 0.12 12.0 2.8 0.25 11.0 2.8 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) PRIMA1 PF16101.5 GBG89759.1 - 0.81 9.7 7.8 1.5 8.9 7.8 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF5320 PF17253.2 GBG89759.1 - 2.9 9.0 14.7 1.3 10.2 2.8 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5320) Dfp1_Him1_M PF08630.10 GBG89759.1 - 5.9 7.1 7.3 1.5 9.1 3.0 2.0 2 0 0 2 2 2 0 Dfp1/Him1, central region Jnk-SapK_ap_N PF09744.9 GBG89760.1 - 0.0047 17.2 1.7 0.0084 16.3 1.7 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Vma12 PF11712.8 GBG89760.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.5 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4407 PF14362.6 GBG89760.1 - 0.2 11.0 2.9 0.23 10.8 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 GBG89760.1 - 6.2 6.9 11.3 0.24 11.4 5.5 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RNA_pol_Rpb2_6 PF00562.28 GBG89761.1 - 1.2e-126 422.9 0.2 1.9e-126 422.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GBG89761.1 - 2.7e-55 187.0 0.1 4.7e-55 186.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 GBG89761.1 - 4.3e-54 183.1 0.0 8.5e-54 182.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GBG89761.1 - 3.2e-36 123.6 0.3 9.5e-36 122.1 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 GBG89761.1 - 5.2e-26 90.6 0.1 1.4e-25 89.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 GBG89761.1 - 1.4e-20 73.3 0.3 3.8e-20 71.9 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 GBG89761.1 - 1.7e-17 63.7 1.6 2.8e-17 63.0 0.6 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Dr_adhesin PF12393.8 GBG89761.1 - 0.17 12.2 0.5 0.57 10.5 0.5 2.0 1 0 0 1 1 1 0 Dr family adhesin AKAP_110 PF05716.13 GBG89762.1 - 0.13 10.5 0.1 0.16 10.1 0.1 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) DUF659 PF04937.15 GBG89763.1 - 2.7e-30 105.3 0.0 5.9e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89763.1 - 4.4e-05 23.2 0.1 8.5e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG89764.1 - 2.6e-30 105.3 0.0 4.1e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG89765.1 - 2.8e-29 101.1 0.0 5.6e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89765.1 - 2.3e-27 95.3 0.0 4.2e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89765.1 - 1.6e-15 57.3 0.0 2.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG89765.1 - 1.2 8.5 29.5 1.8 7.9 29.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG89765.1 - 2.3 7.4 28.1 3.6 6.8 28.1 1.2 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 GBG89765.1 - 9.5 6.5 15.2 16 5.8 15.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_M16_M PF16187.5 GBG89766.1 - 8.6e-55 186.0 0.0 3.9e-27 95.3 0.0 2.2 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 GBG89766.1 - 3.3e-06 27.2 0.0 2.2e-05 24.6 0.0 2.3 3 0 0 3 3 3 1 Peptidase M16 inactive domain RVT_1 PF00078.27 GBG89767.1 - 7.1e-14 51.9 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M16 PF00675.20 GBG89768.1 - 9.7e-33 113.2 0.0 2.2e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PACT_coil_coil PF10495.9 GBG89768.1 - 7.4e-05 23.3 0.2 0.064 13.8 0.0 2.5 2 0 0 2 2 2 2 Pericentrin-AKAP-450 domain of centrosomal targeting protein HIG_1_N PF04588.13 GBG89771.1 - 4.2e-18 65.3 2.5 9.3e-18 64.2 2.5 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MMR_HSR1_Xtn PF16897.5 GBG89772.1 - 2.5e-42 143.2 0.4 4.8e-42 142.3 0.4 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 GBG89772.1 - 3e-24 84.8 0.1 5.6e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 GBG89772.1 - 2.3e-21 76.0 0.0 5.6e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG89772.1 - 3e-11 43.1 0.0 5.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GBG89772.1 - 0.0011 19.0 0.1 0.34 11.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.6 GBG89772.1 - 0.099 12.9 0.0 1.8 8.8 0.1 2.8 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 GBG89772.1 - 0.13 12.8 0.1 7.4 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain COG2 PF06148.11 GBG89774.1 - 1.2e-35 122.5 1.9 2.9e-35 121.2 0.2 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 GBG89774.1 - 0.00015 21.8 0.0 0.0018 18.3 0.0 2.8 3 0 0 3 3 3 1 Vps51/Vps67 PH PF00169.29 GBG89775.1 - 1.2e-05 25.7 0.0 2.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 PH domain CDC45 PF02724.14 GBG89775.1 - 0.0038 15.6 9.1 0.0048 15.3 9.1 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF4746 PF15928.5 GBG89775.1 - 0.019 14.4 3.4 0.029 13.8 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 GBG89775.1 - 1.8 6.7 17.4 2.5 6.2 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG89775.1 - 2.8 6.3 18.2 3.9 5.8 18.2 1.1 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 GBG89775.1 - 4 7.2 7.3 6.7 6.5 7.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG89775.1 - 4.5 6.6 18.8 6.8 6.0 18.8 1.2 1 0 0 1 1 1 0 SDA1 Coilin_N PF15862.5 GBG89775.1 - 4.9 7.0 6.4 34 4.2 6.4 2.2 1 1 0 1 1 1 0 Coilin N-terminus TFIIF_alpha PF05793.12 GBG89775.1 - 5.5 5.5 18.8 9.2 4.7 18.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PH PF00169.29 GBG89776.1 - 0.00079 19.9 0.4 0.0017 18.8 0.4 1.6 1 0 0 1 1 1 1 PH domain CDC45 PF02724.14 GBG89776.1 - 0.0023 16.3 8.8 0.0028 16.0 8.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF4746 PF15928.5 GBG89776.1 - 0.0085 15.6 2.6 0.012 15.1 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Nop14 PF04147.12 GBG89776.1 - 0.92 7.6 16.8 1.3 7.2 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG89776.1 - 1.2 7.5 17.4 1.7 7.0 17.4 1.1 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 GBG89776.1 - 3 7.6 7.4 5.1 6.8 7.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG89776.1 - 3.1 7.1 18.7 4.7 6.5 18.7 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG89776.1 - 4.5 5.7 19.0 7.9 4.9 19.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Coilin_N PF15862.5 GBG89776.1 - 9.1 6.1 8.0 31 4.4 6.7 2.3 2 1 0 2 2 2 0 Coilin N-terminus Presenilin PF01080.17 GBG89776.1 - 9.5 4.9 8.4 14 4.3 8.4 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG89777.1 - 0.0026 16.2 9.0 0.0031 15.9 9.0 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF4746 PF15928.5 GBG89777.1 - 0.0083 15.6 2.6 0.012 15.1 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Nop14 PF04147.12 GBG89777.1 - 0.91 7.7 16.8 1.2 7.2 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG89777.1 - 1.2 7.5 17.4 1.7 7.0 17.4 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 GBG89777.1 - 2.8 6.4 18.3 4.9 5.6 18.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.12 GBG89777.1 - 2.9 7.6 7.4 5 6.9 7.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 GBG89777.1 - 3.1 7.1 18.7 4.7 6.5 18.7 1.2 1 0 0 1 1 1 0 SDA1 Coilin_N PF15862.5 GBG89777.1 - 8.9 6.1 8.0 30 4.4 6.7 2.3 2 1 0 2 2 2 0 Coilin N-terminus Presenilin PF01080.17 GBG89777.1 - 9.3 4.9 8.4 14 4.3 8.4 1.2 1 0 0 1 1 1 0 Presenilin zf-CCHC PF00098.23 GBG89779.1 - 1.3e-07 31.4 1.8 2.8e-07 30.3 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG89779.1 - 0.005 16.5 0.6 0.012 15.3 0.6 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG89779.1 - 0.082 12.7 0.9 0.17 11.6 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3752 PF12572.8 GBG89780.1 - 0.59 10.6 7.9 0.14 12.7 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) DLH PF01738.18 GBG89781.1 - 0.00028 20.5 0.6 0.0027 17.3 0.6 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family TcdB_toxin_midN PF12256.8 GBG89781.1 - 0.02 14.3 0.1 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region Esterase_phd PF10503.9 GBG89781.1 - 0.073 12.5 2.4 7 6.1 0.4 2.5 3 0 0 3 3 3 0 Esterase PHB depolymerase ABC1 PF03109.16 GBG89782.1 - 1.1e-14 54.7 0.0 2e-12 47.3 0.0 2.7 2 1 0 2 2 2 1 ABC1 family SPX PF03105.19 GBG89782.1 - 0.92 9.4 5.5 13 5.6 2.0 2.3 2 0 0 2 2 2 0 SPX domain SelP_N PF04592.14 GBG89782.1 - 1 8.7 21.6 1.7 8.0 21.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 GBG89782.1 - 3.2 6.2 4.4 6 5.3 4.4 1.3 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 GBG89783.1 - 0.024 13.9 2.1 0.033 13.4 2.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 GBG89783.1 - 0.15 10.9 2.5 0.15 10.8 2.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NYAP_C PF15452.6 GBG89783.1 - 1 9.2 7.1 2.5 7.9 7.1 1.7 1 1 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter V_ATPase_I PF01496.19 GBG89783.1 - 6 4.7 4.4 7.5 4.3 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc4 PF05132.14 GBG89783.1 - 6.3 7.2 7.9 21 5.5 7.9 2.1 1 1 0 1 1 1 0 RNA polymerase III RPC4 PTPRCAP PF15713.5 GBG89783.1 - 6.9 6.9 23.1 15 5.9 23.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Mito_carr PF00153.27 GBG89785.1 - 6.8e-57 189.4 4.2 2.5e-18 65.8 0.1 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Na_trans_assoc PF06512.13 GBG89786.1 - 6.8e-05 23.2 0.0 0.00016 22.0 0.0 1.7 1 1 0 1 1 1 1 Sodium ion transport-associated Cwf_Cwc_15 PF04889.12 GBG89786.1 - 0.14 11.9 18.9 0.17 11.6 18.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG89786.1 - 3.1 5.9 22.1 3.5 5.7 22.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG89786.1 - 3.6 5.8 16.4 4.2 5.6 16.4 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG89786.1 - 4.1 6.7 22.1 4.8 6.5 22.1 1.1 1 0 0 1 1 1 0 SDA1 Rieske PF00355.26 GBG89787.1 - 3.2e-16 59.0 0.0 5.5e-15 55.1 0.0 2.3 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG89787.1 - 0.00029 20.9 0.0 0.0011 19.1 0.0 2.1 1 0 0 1 1 1 1 Pheophorbide a oxygenase SDA1 PF05285.12 GBG89787.1 - 0.46 9.8 29.8 0.56 9.6 1.7 2.2 2 0 0 2 2 2 0 SDA1 SpoIIIAH PF12685.7 GBG89787.1 - 0.61 9.9 10.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Na_trans_assoc PF06512.13 GBG89787.1 - 1.6 9.0 13.4 6.3 7.0 10.3 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated Nop14 PF04147.12 GBG89787.1 - 9.2 4.3 31.1 2.7 6.1 20.8 2.1 2 0 0 2 2 2 0 Nop14-like family DDE_Tnp_4 PF13359.6 GBG89788.1 - 1.4e-33 115.8 0.0 2e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89788.1 - 1.9e-16 60.3 0.0 3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89788.1 - 2.9e-05 23.8 0.0 0.26 10.9 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG89788.1 - 0.018 15.4 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain PGA2 PF07543.12 GBG89789.1 - 0.27 11.2 1.5 0.54 10.2 1.5 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 CAP_N PF01213.19 GBG89790.1 - 4 6.8 6.3 7.6 5.9 6.3 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aminotran_1_2 PF00155.21 GBG89792.1 - 3.4e-84 283.1 0.0 4e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RT_RNaseH_2 PF17919.1 GBG89793.1 - 2.5e-34 117.3 0.1 5.4e-34 116.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89793.1 - 4.8e-31 107.2 0.1 1e-30 106.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG89793.1 - 0.41 10.8 2.6 1 9.6 2.6 1.7 1 0 0 1 1 1 0 Zinc knuckle CTU2 PF10288.9 GBG89793.1 - 0.57 10.4 2.3 0.73 10.1 0.2 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 FRG1 PF06229.12 GBG89794.1 - 0.021 14.5 3.6 0.035 13.8 3.6 1.3 1 0 0 1 1 1 0 FRG1-like domain Nop53 PF07767.11 GBG89794.1 - 0.079 12.3 30.6 0.12 11.8 30.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNA_pol_Rpc4 PF05132.14 GBG89794.1 - 0.37 11.2 4.6 0.6 10.5 4.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 GBG89794.1 - 2.5 6.8 7.4 3 6.5 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GBG89794.1 - 4.7 5.3 26.1 7 4.7 26.1 1.2 1 0 0 1 1 1 0 Nop14-like family PPL5 PF18168.1 GBG89794.1 - 8.7 5.5 7.2 12 5.0 7.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Rieske PF00355.26 GBG89795.1 - 7.5e-17 61.1 0.0 2.2e-16 59.6 0.0 1.8 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG89795.1 - 5.4e-11 42.5 0.1 2.2e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Pheophorbide a oxygenase DUF659 PF04937.15 GBG89796.1 - 9.1e-17 61.3 0.0 1.3e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG89796.1 - 0.02 15.1 0.1 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Integrase core domain TFIIF_alpha PF05793.12 GBG89796.1 - 2.3 6.7 15.2 4.1 5.9 15.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 GBG89796.1 - 7.6 4.5 14.9 9.8 4.1 14.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Rieske PF00355.26 GBG89798.1 - 2.3e-16 59.5 0.0 6.1e-16 58.1 0.0 1.7 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG89798.1 - 8.6e-08 32.2 0.0 1.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Pheophorbide a oxygenase RVT_1 PF00078.27 GBG89799.1 - 0.033 13.7 0.0 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_1 PF00036.32 GBG89801.1 - 2.2e-27 92.5 12.6 2.6e-08 32.8 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GBG89801.1 - 5.2e-26 90.9 6.0 8.8e-13 48.5 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG89801.1 - 1.1e-25 87.3 7.0 6.3e-09 35.1 0.4 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GBG89801.1 - 1.2e-18 66.7 11.9 1.6e-08 34.2 0.1 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GBG89801.1 - 5.9e-16 57.2 9.8 0.0002 20.7 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 GBG89801.1 - 2.7e-13 50.0 0.1 1.3e-07 31.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GBG89801.1 - 5e-09 36.1 2.6 0.0002 21.3 0.0 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GBG89801.1 - 5.2e-06 26.8 0.1 0.1 12.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 GBG89801.1 - 1.2e-05 25.2 0.2 0.55 10.3 0.0 3.2 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) TerB PF05099.13 GBG89801.1 - 0.0002 21.4 0.8 0.21 11.5 0.2 2.4 2 1 1 3 3 3 2 Tellurite resistance protein TerB EF-hand_14 PF17959.1 GBG89801.1 - 0.00034 20.9 0.2 0.014 15.7 0.1 2.4 1 1 1 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 GBG89801.1 - 0.0027 17.5 0.5 0.55 10.1 0.0 3.0 1 1 2 3 3 3 1 EF hand VCBS PF13517.6 GBG89801.1 - 0.003 18.1 0.4 0.053 14.1 0.0 2.2 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF2666 PF10869.8 GBG89801.1 - 0.0051 17.0 1.4 1.7 8.9 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2666) Adenine_glyco PF03352.13 GBG89801.1 - 0.01 15.6 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase Caleosin PF05042.13 GBG89801.1 - 0.032 14.1 1.0 9.8 6.1 0.0 3.0 1 1 2 3 3 3 0 Caleosin related protein Dockerin_1 PF00404.18 GBG89801.1 - 0.033 14.4 5.1 4.6 7.5 5.1 3.1 1 1 0 1 1 1 0 Dockerin type I domain Toprim_4 PF13662.6 GBG89801.1 - 0.034 14.6 0.2 2.5 8.6 0.0 2.5 2 1 1 3 3 3 0 Toprim domain DUF5580 PF17743.1 GBG89801.1 - 0.039 12.5 0.0 0.17 10.4 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5580) Toprim_2 PF13155.6 GBG89801.1 - 0.043 14.3 0.4 0.43 11.0 0.1 2.1 1 1 1 2 2 2 0 Toprim-like DUF1456 PF07308.13 GBG89801.1 - 0.043 14.2 1.2 2.1 8.8 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) RTX_C PF08339.10 GBG89801.1 - 0.068 13.2 1.1 1.1 9.2 0.1 2.2 1 1 0 2 2 2 0 RTX C-terminal domain GatB_Yqey PF02637.18 GBG89801.1 - 0.074 12.9 1.0 0.24 11.3 1.0 1.8 1 1 1 2 2 2 0 GatB domain MotA_activ PF09114.10 GBG89801.1 - 0.085 13.0 0.5 0.65 10.2 0.1 2.1 2 1 0 2 2 2 0 Transcription factor MotA, activation domain Retrotrans_gag PF03732.17 GBG89802.1 - 0.014 15.6 2.5 0.057 13.7 0.1 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein Lipin_mid PF16876.5 GBG89802.1 - 0.065 13.4 1.0 0.31 11.2 0.0 2.5 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain CENP-K PF11802.8 GBG89802.1 - 0.079 12.5 1.4 0.13 11.8 1.4 1.4 1 0 0 1 1 1 0 Centromere-associated protein K CREPT PF16566.5 GBG89802.1 - 1.8 8.7 6.6 7.6 6.7 1.8 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1612 PF07756.12 GBG89802.1 - 4.7 7.5 11.3 0.49 10.6 0.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1612) Exo_endo_phos PF03372.23 GBG89803.1 - 1.6e-15 57.3 0.5 3.5e-15 56.2 0.5 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GBG89803.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Ribosomal_60s PF00428.19 GBG89804.1 - 5.2e-22 78.2 7.7 8.1e-22 77.6 7.7 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 GBG89804.1 - 0.14 10.6 0.2 0.18 10.3 0.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CAP PF00188.26 GBG89806.1 - 1.7e-23 83.8 7.4 1.7e-23 83.8 7.4 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family RAP1 PF07218.11 GBG89806.1 - 8.8 4.5 8.5 11 4.2 8.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nop14 PF04147.12 GBG89807.1 - 0.00032 19.1 14.8 0.00038 18.8 14.8 1.0 1 0 0 1 1 1 1 Nop14-like family Presenilin PF01080.17 GBG89807.1 - 0.0033 16.3 2.0 0.0038 16.1 2.0 1.2 1 0 0 1 1 1 1 Presenilin SDA1 PF05285.12 GBG89807.1 - 0.017 14.5 19.3 0.02 14.3 19.3 1.1 1 0 0 1 1 1 0 SDA1 SLC12 PF03522.15 GBG89807.1 - 0.044 12.8 0.5 0.056 12.5 0.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 GBG89807.1 - 0.12 10.7 13.1 0.14 10.4 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 GBG89807.1 - 0.18 11.8 34.4 0.26 11.3 34.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HSP70 PF00012.20 GBG89807.1 - 0.38 8.9 8.4 0.58 8.3 8.4 1.2 1 0 0 1 1 1 0 Hsp70 protein DNA_pol_phi PF04931.13 GBG89807.1 - 0.99 7.4 30.7 1.4 7.0 30.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 GBG89807.1 - 3.4 6.7 23.7 4.4 6.3 23.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) N6_N4_Mtase PF01555.18 GBG89808.1 - 8.4e-09 35.5 6.8 1.3e-06 28.3 0.0 3.9 4 0 0 4 4 4 2 DNA methylase CDC45 PF02724.14 GBG89808.1 - 0.0019 16.6 24.4 0.0019 16.6 24.4 2.0 2 0 0 2 2 2 1 CDC45-like protein UPF0020 PF01170.18 GBG89808.1 - 0.1 12.3 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Rxt3 PF08642.10 GBG89809.1 - 0.075 13.8 0.3 0.17 12.7 0.3 1.6 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 SRP9-21 PF05486.12 GBG89809.1 - 0.94 9.9 3.7 4 7.9 3.7 2.0 1 1 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) SOUL PF04832.12 GBG89810.1 - 1.1e-44 152.6 0.8 1.8e-27 96.5 0.1 2.1 1 1 1 2 2 2 2 SOUL heme-binding protein SpoVIF PF14069.6 GBG89810.1 - 0.025 14.4 0.1 0.041 13.7 0.1 1.3 1 0 0 1 1 1 0 Stage VI sporulation protein F GST_N PF02798.20 GBG89811.1 - 1.6e-16 60.4 0.0 3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GBG89811.1 - 2.6e-14 53.4 0.0 4.7e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GBG89811.1 - 7.5e-14 51.8 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GBG89811.1 - 2.7e-13 50.0 0.0 7.2e-13 48.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GBG89811.1 - 3.3e-09 36.8 0.0 5.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GBG89811.1 - 1.4e-07 31.4 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3669 PF12417.8 GBG89811.1 - 0.1 12.8 0.1 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 Zinc finger protein GST_N_5 PF18485.1 GBG89811.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Integrase_H2C2 PF17921.1 GBG89812.1 - 2e-19 69.4 0.4 4.3e-19 68.4 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG89812.1 - 1.7e-15 57.1 0.1 8.3e-15 54.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89812.1 - 2.5e-14 53.4 0.0 1e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89812.1 - 5.3e-13 48.9 0.0 1.2e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GST_C PF00043.25 GBG89812.1 - 7.4e-11 42.1 0.1 1.8e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GBG89812.1 - 1.4e-08 34.9 0.0 3.8e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain rve PF00665.26 GBG89812.1 - 2.1e-06 27.9 0.0 7e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain GST_C_3 PF14497.6 GBG89812.1 - 2.7e-05 24.3 0.0 0.00011 22.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GBG89812.1 - 0.00034 21.0 0.0 0.0012 19.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GBG89812.1 - 0.00053 20.0 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Retrotrans_gag PF03732.17 GBG89812.1 - 0.0058 16.9 0.0 0.021 15.1 0.0 1.9 2 0 0 2 2 1 1 Retrotransposon gag protein GST_N_2 PF13409.6 GBG89812.1 - 0.028 14.7 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DDE_Tnp_4 PF13359.6 GBG89813.1 - 4.3e-28 98.0 0.0 6.5e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89813.1 - 3e-17 62.9 0.0 4.1e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89813.1 - 1.5e-05 24.7 0.3 0.00052 19.7 0.3 2.4 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG89813.1 - 0.19 12.1 0.5 3 8.3 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG89814.1 - 0.065 13.6 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG89814.1 - 0.075 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG89815.1 - 1.2e-25 90.0 0.1 2e-25 89.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89815.1 - 6e-15 55.4 0.0 9.7e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89815.1 - 0.0022 17.7 0.7 0.093 12.4 0.7 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF2052 PF09747.9 GBG89816.1 - 1e-34 120.4 50.1 8.1e-29 101.2 50.1 3.3 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) BUD22 PF09073.10 GBG89816.1 - 0.092 12.1 23.9 0.13 11.5 23.9 1.4 1 0 0 1 1 1 0 BUD22 PRTP PF01366.18 GBG89816.1 - 0.3 9.1 4.4 0.37 8.8 4.4 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein SAPS PF04499.15 GBG89816.1 - 1.8 7.3 7.8 2 7.1 7.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GBG89816.1 - 2.3 6.9 11.9 2.9 6.5 11.9 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 GBG89816.1 - 2.4 6.2 34.2 3.7 5.6 34.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG89816.1 - 3.4 5.8 26.4 5.1 5.3 26.4 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG89816.1 - 3.6 6.1 33.0 6.8 5.1 33.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ank_2 PF12796.7 GBG89817.1 - 1.1e-63 211.7 16.9 5.8e-19 68.5 0.3 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GBG89817.1 - 1.3e-42 138.9 0.4 2.9e-05 24.1 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 GBG89817.1 - 4.7e-39 131.2 13.2 2.5e-05 24.5 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 GBG89817.1 - 7.4e-38 128.5 0.1 2.5e-09 37.5 0.0 4.5 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG89817.1 - 5.3e-37 125.4 13.3 2.4e-07 30.9 0.1 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) PTS_IIA PF02255.16 GBG89817.1 - 0.33 11.0 5.5 5.5 7.1 0.0 3.4 1 1 2 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit Candida_ALS PF05792.13 GBG89817.1 - 8.8 7.0 6.9 40 4.9 0.0 3.8 5 0 0 5 5 5 0 Candida agglutinin-like (ALS) VWA_3_C PF18571.1 GBG89817.1 - 9.2 6.2 12.8 91 3.0 0.4 5.3 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain Ank_2 PF12796.7 GBG89818.1 - 8.3e-64 212.2 16.9 5.5e-19 68.5 0.3 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GBG89818.1 - 1e-42 139.2 0.4 2.8e-05 24.2 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 GBG89818.1 - 3.7e-39 131.5 13.2 2.4e-05 24.6 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 GBG89818.1 - 6.3e-38 128.7 0.1 2.4e-09 37.5 0.0 4.5 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG89818.1 - 3.4e-37 126.0 13.2 2.3e-07 30.9 0.1 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) PTS_IIA PF02255.16 GBG89818.1 - 0.29 11.2 5.5 5.5 7.1 0.0 3.4 1 1 4 5 5 5 0 PTS system, Lactose/Cellobiose specific IIA subunit VWA_3_C PF18571.1 GBG89818.1 - 8 6.4 12.8 88 3.1 0.4 5.3 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain Candida_ALS PF05792.13 GBG89818.1 - 8.5 7.1 6.9 39 4.9 0.0 3.8 5 0 0 5 5 5 0 Candida agglutinin-like (ALS) zf-CDGSH PF09360.10 GBG89819.1 - 6.8e-10 39.0 0.4 1.3e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type WD40 PF00400.32 GBG89820.1 - 1.1e-24 86.2 7.9 2.4e-06 28.2 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat DnaJ PF00226.31 GBG89820.1 - 1.6e-19 69.7 0.0 4.8e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain ANAPC4_WD40 PF12894.7 GBG89820.1 - 1e-10 41.7 0.2 0.015 15.6 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 GBG89820.1 - 4.9e-05 23.1 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ge1_WD40 PF16529.5 GBG89820.1 - 0.00042 19.4 0.1 0.14 11.1 0.0 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GBG89820.1 - 0.0037 17.2 0.0 0.32 10.9 0.0 3.2 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 GBG89821.1 - 2.6e-25 88.2 7.9 1.9e-06 28.5 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat DnaJ PF00226.31 GBG89821.1 - 1.1e-19 70.2 0.2 3.7e-19 68.6 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain ANAPC4_WD40 PF12894.7 GBG89821.1 - 4.3e-11 42.9 0.2 0.012 15.9 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 GBG89821.1 - 3.4e-05 23.6 0.0 9.9e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ge1_WD40 PF16529.5 GBG89821.1 - 0.00024 20.2 0.1 0.11 11.5 0.0 2.5 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GBG89821.1 - 0.0017 18.3 0.0 0.24 11.2 0.0 3.4 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF659 PF04937.15 GBG89823.1 - 2.9e-31 108.4 0.0 4.4e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG89823.1 - 1.9e-10 40.4 0.1 4.1e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Fasciclin PF02469.22 GBG89825.1 - 3.1e-10 40.3 0.0 4.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Pkinase_Tyr PF07714.17 GBG89826.1 - 2.8e-37 128.4 0.0 2.1e-36 125.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG89826.1 - 2.4e-35 122.2 0.0 3.8e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LysM PF01476.20 GBG89826.1 - 6.2e-10 39.0 0.0 0.009 16.1 0.1 3.4 3 0 0 3 3 3 3 LysM domain APH PF01636.23 GBG89826.1 - 0.0023 17.9 0.1 1.2 9.0 0.3 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family CwsA PF10814.8 GBG89826.1 - 0.12 12.5 0.1 0.45 10.7 0.2 1.9 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA DUF979 PF06166.12 GBG89826.1 - 0.26 10.4 0.0 0.45 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF979) DnaJ_CXXCXGXG PF00684.19 GBG89826.1 - 2.2 8.7 5.0 5.1 7.5 5.0 1.6 1 0 0 1 1 1 0 DnaJ central domain Integrase_H2C2 PF17921.1 GBG89827.1 - 2e-05 24.6 0.5 4.6e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain SlyX PF04102.12 GBG89827.1 - 0.1 13.2 0.6 0.6 10.8 0.0 2.7 4 0 0 4 4 4 0 SlyX PKcGMP_CC PF16808.5 GBG89827.1 - 1.7 8.5 5.4 3.9 7.4 1.0 3.0 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RT_RNaseH_2 PF17919.1 GBG89829.1 - 6.7e-27 93.5 0.1 1.2e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89829.1 - 5.5e-18 64.8 0.8 9.6e-18 64.0 0.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG89829.1 - 5.7e-14 52.3 0.0 1.2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG89829.1 - 1.5e-06 28.4 0.1 1.2e-05 25.5 0.0 2.4 2 1 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG89829.1 - 0.21 11.8 1.3 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 H2C2 zinc finger RVT_1 PF00078.27 GBG89830.1 - 7.4e-29 100.8 0.1 1.5e-28 99.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG89830.1 - 2.4e-13 50.3 0.1 5e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG89830.1 - 7.4e-07 29.7 0.0 4.3e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89830.1 - 0.00014 22.4 0.0 0.00029 21.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG89830.1 - 0.0061 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG89830.1 - 0.072 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF1564 PF07600.11 GBG89830.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Beta-lactamase2 PF13354.6 GBG89831.1 - 7.5e-06 25.7 0.0 9.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Myb_DNA-binding PF00249.31 GBG89833.1 - 8.5e-13 48.3 0.2 2.3e-05 24.5 0.3 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG89833.1 - 1.5e-07 31.6 2.8 0.0017 18.6 0.3 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain TFIIA PF03153.13 GBG89833.1 - 0.00011 22.3 22.4 0.00011 22.3 22.4 7.4 8 1 1 9 9 9 2 Transcription factor IIA, alpha/beta subunit Myb_DNA-bind_7 PF15963.5 GBG89833.1 - 0.00041 20.2 0.1 0.00041 20.2 0.1 3.9 4 0 0 4 4 4 1 Myb DNA-binding like Band_3_cyto PF07565.13 GBG89833.1 - 0.61 9.9 7.2 2 8.1 7.2 1.9 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MDM10 PF12519.8 GBG89833.1 - 3.1 6.5 5.7 7.6 5.3 5.7 1.6 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 EMC3_TMCO1 PF01956.16 GBG89833.1 - 7.7 6.2 8.2 19 5.0 8.2 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Pyridoxal_deC PF00282.19 GBG89835.1 - 3.3e-89 299.2 0.0 4e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Thioredoxin PF00085.20 GBG89837.1 - 2.3e-19 69.3 0.1 3.5e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GBG89837.1 - 0.0039 17.5 0.0 0.009 16.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GBG89837.1 - 0.0051 17.0 0.3 0.012 15.7 0.3 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GBG89837.1 - 0.0074 16.7 0.1 0.029 14.8 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GBG89837.1 - 0.0079 15.6 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 GBG89837.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family RT_RNaseH_2 PF17919.1 GBG89838.1 - 1.4e-33 114.9 0.0 2.6e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89838.1 - 9.6e-33 113.6 0.1 1.4e-32 113.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89838.1 - 2.6e-28 98.4 0.1 6e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5095 PF17016.5 GBG89838.1 - 0.15 11.7 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Vps54_N PF10475.9 GBG89839.1 - 1.7e-73 247.5 6.1 2.3e-73 247.0 6.1 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Ada3 PF10198.9 GBG89839.1 - 0.061 13.5 0.4 0.16 12.1 0.4 1.7 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Integrase_H2C2 PF17921.1 GBG89840.1 - 4.3e-14 52.4 0.3 1e-13 51.2 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG89840.1 - 6.5e-09 36.2 0.0 2e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89840.1 - 3.8e-05 24.2 0.0 0.00012 22.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG89840.1 - 0.0063 16.3 0.3 0.017 14.9 0.3 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG89840.1 - 0.041 14.1 3.3 0.27 11.6 0.0 2.9 3 0 0 3 3 3 0 Retrotransposon gag protein RVP PF00077.20 GBG89840.1 - 0.047 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Ras PF00071.22 GBG89841.1 - 1.3e-24 86.6 0.1 1.4e-24 86.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG89841.1 - 1.7e-23 83.1 0.1 1.8e-23 83.0 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG89841.1 - 1e-07 31.6 0.1 1.1e-07 31.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GBG89841.1 - 2.8e-05 24.2 0.0 3.2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GBG89841.1 - 0.00031 21.2 0.0 0.00032 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 GBG89841.1 - 0.0012 18.6 0.2 0.0026 17.5 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GBG89841.1 - 0.002 17.7 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region Gtr1_RagA PF04670.12 GBG89841.1 - 0.0047 16.3 0.0 0.0059 16.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 GBG89841.1 - 0.0049 16.2 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Septin ATP_bind_1 PF03029.17 GBG89841.1 - 0.0058 16.4 0.6 0.61 9.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.20 GBG89841.1 - 0.0064 15.7 0.2 0.039 13.1 0.0 1.8 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.9 GBG89841.1 - 0.0067 16.2 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 GBG89841.1 - 0.0075 16.7 0.1 0.008 16.6 0.1 1.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG89841.1 - 0.0097 16.2 0.1 0.019 15.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 GBG89841.1 - 0.011 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 GBG89841.1 - 0.014 14.8 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NB-ARC PF00931.22 GBG89841.1 - 0.019 14.2 0.3 0.035 13.3 0.1 1.3 1 1 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 GBG89841.1 - 0.028 14.3 0.1 0.029 14.3 0.1 1.3 1 1 0 1 1 1 0 RsgA GTPase MCM PF00493.23 GBG89841.1 - 0.042 13.0 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain DLIC PF05783.11 GBG89841.1 - 0.045 12.6 0.1 0.048 12.5 0.1 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) VirE PF05272.11 GBG89841.1 - 0.051 13.3 0.1 0.071 12.8 0.0 1.3 1 1 0 1 1 1 0 Virulence-associated protein E ATPase PF06745.13 GBG89841.1 - 0.06 12.7 0.1 0.063 12.6 0.1 1.1 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 GBG89841.1 - 0.072 13.1 0.1 0.12 12.4 0.0 1.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GBG89841.1 - 0.085 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GBG89841.1 - 0.13 12.8 0.1 0.23 12.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 GBG89841.1 - 0.18 11.8 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3449 PF11931.8 GBG89844.1 - 0.13 12.1 0.3 0.25 11.1 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) zinc_ribbon_4 PF13717.6 GBG89844.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain gag-asp_proteas PF13975.6 GBG89845.1 - 7.9e-05 23.2 0.0 0.00021 21.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG89845.1 - 0.00016 21.4 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89845.1 - 0.00019 22.0 0.0 0.00045 20.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG89845.1 - 0.0002 21.2 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG89845.1 - 0.049 13.9 3.1 0.062 13.6 0.5 2.5 2 1 1 3 3 3 0 Retrotransposon gag protein DUF4834 PF16118.5 GBG89846.1 - 8.2 7.5 9.4 0.88 10.6 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) THB PF18362.1 GBG89847.1 - 0.019 14.5 0.1 0.043 13.4 0.1 1.6 1 0 0 1 1 1 0 Tri-helix bundle domain Lectin_N PF03954.14 GBG89847.1 - 0.073 12.8 7.3 0.41 10.4 5.7 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain FlaC_arch PF05377.11 GBG89847.1 - 3.7 8.0 7.9 2.6 8.5 0.2 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Lactamase_B_2 PF12706.7 GBG89848.1 - 4.5e-11 42.7 0.2 1.7e-10 40.8 0.2 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GBG89848.1 - 0.0019 18.2 0.6 0.023 14.7 0.1 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DDE_Tnp_4 PF13359.6 GBG89849.1 - 1e-17 64.3 0.0 1.9e-17 63.4 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89849.1 - 1.5e-08 34.5 0.0 2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89849.1 - 0.0026 17.4 0.0 0.0058 16.3 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG89850.1 - 2.4e-06 27.9 0.6 6.1e-06 26.5 0.6 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TMEM154 PF15102.6 GBG89850.1 - 0.78 9.6 5.1 0.27 11.1 0.6 2.5 2 0 0 2 2 2 0 TMEM154 protein family RT_RNaseH_2 PF17919.1 GBG89852.1 - 3.4e-30 104.0 0.0 8e-15 54.7 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89852.1 - 5.2e-29 100.6 0.0 2.1e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89852.1 - 2.3e-15 56.4 0.1 2.3e-15 56.4 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG89852.1 - 0.00026 21.1 0.1 0.00055 20.1 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Helicase_C PF00271.31 GBG89854.1 - 3.2e-10 40.3 0.0 6.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 GBG89854.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 GBG89854.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Helicase_C PF00271.31 GBG89855.1 - 3.1e-10 40.4 0.0 5.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GBG89855.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase NTPase_I-T PF01931.18 GBG89856.1 - 1.5e-46 158.1 0.0 1.7e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 NTPase_I-T PF01931.18 GBG89857.1 - 8.1e-36 123.3 0.0 9.6e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF84 F-box-like PF12937.7 GBG89858.1 - 2.6e-07 30.4 0.2 7.8e-07 28.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG89858.1 - 0.0013 18.6 0.1 0.0032 17.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain Nebulin PF00880.18 GBG89858.1 - 0.42 10.6 1.4 0.79 9.7 1.4 1.4 1 0 0 1 1 1 0 Nebulin repeat LRV_FeS PF05484.11 GBG89858.1 - 0.63 10.1 3.5 0.42 10.6 1.1 2.0 2 0 0 2 2 2 0 LRV protein FeS4 cluster Pkinase PF00069.25 GBG89859.1 - 1.2e-08 34.7 0.0 1.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 GBG89859.1 - 5.2e-07 29.4 0.2 0.44 10.9 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Pkinase_Tyr PF07714.17 GBG89859.1 - 2.6e-05 23.6 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 GBG89859.1 - 0.0047 17.4 0.0 0.45 11.1 0.0 3.6 2 1 1 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 GBG89859.1 - 0.014 15.5 0.3 0.04 13.9 0.3 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Myb_DNA-bind_4 PF13837.6 GBG89860.1 - 2.1e-07 31.2 4.9 3.1e-07 30.7 4.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG89860.1 - 0.016 15.3 3.0 0.061 13.4 3.0 1.9 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain RAP80_UIM PF18282.1 GBG89860.1 - 0.12 12.1 0.4 0.23 11.3 0.4 1.4 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Enkurin PF13864.6 GBG89860.1 - 0.19 12.2 3.4 0.41 11.1 3.4 1.6 1 1 0 1 1 1 0 Calmodulin-binding Vps35 PF03635.17 GBG89861.1 - 6e-11 41.6 0.3 7.6e-08 31.3 0.0 2.6 3 0 0 3 3 3 2 Vacuolar protein sorting-associated protein 35 RT_RNaseH_2 PF17919.1 GBG89861.1 - 5.3e-10 39.2 0.0 1.3e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89861.1 - 0.0013 18.3 0.0 0.0033 17.0 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) EMP24_GP25L PF01105.24 GBG89861.1 - 0.15 12.0 3.3 6.1 6.7 0.0 2.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Retrotrans_gag PF03732.17 GBG89861.1 - 0.37 11.1 0.0 0.37 11.1 0.0 4.5 5 0 0 5 5 5 0 Retrotransposon gag protein SPACA9 PF15120.6 GBG89861.1 - 1.4 8.6 6.1 0.1 12.4 0.6 2.0 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 Peptidase_U32 PF01136.19 GBG89862.1 - 0.052 12.7 0.7 0.33 10.1 0.1 2.0 2 0 0 2 2 2 0 Peptidase family U32 Nop PF01798.18 GBG89864.1 - 8.3e-86 287.2 0.3 8.3e-86 287.2 0.3 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin RVT_1 PF00078.27 GBG89864.1 - 2.9e-31 108.7 0.1 1.1e-30 106.9 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) NOP5NT PF08156.13 GBG89864.1 - 3.9e-09 36.8 0.2 1.4e-08 35.0 0.2 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain FtsJ PF01728.19 GBG89865.1 - 9.9e-38 130.0 0.0 7.8e-37 127.1 0.0 2.3 2 1 0 2 2 2 1 FtsJ-like methyltransferase Ubiquitin_4 PF18036.1 GBG89865.1 - 5.4e-27 93.7 0.0 8.5e-27 93.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Methyltransf_25 PF13649.6 GBG89865.1 - 0.021 15.5 0.0 0.05 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ubiquitin PF00240.23 GBG89865.1 - 0.063 13.0 0.0 0.67 9.8 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin family Methyltransf_23 PF13489.6 GBG89865.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain FERM_N PF09379.10 GBG89865.1 - 0.18 11.8 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 FERM N-terminal domain RVT_1 PF00078.27 GBG89868.1 - 4.8e-32 111.3 0.0 8e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GDI PF00996.18 GBG89870.1 - 4.8e-35 120.9 0.0 3.5e-13 48.9 0.0 3.2 3 0 0 3 3 3 3 GDP dissociation inhibitor zf-RING_2 PF13639.6 GBG89871.1 - 3.1e-12 46.6 5.6 3.1e-12 46.6 5.6 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GBG89871.1 - 4.6e-10 39.2 6.0 4.6e-10 39.2 6.0 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG89871.1 - 1.7e-08 34.6 4.7 1.7e-08 34.6 4.7 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GBG89871.1 - 2.4e-07 30.5 7.4 2.4e-07 30.5 7.4 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 GBG89871.1 - 1.6e-06 27.9 22.3 6.8e-05 22.7 7.9 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING_UBOX PF13445.6 GBG89871.1 - 1.7e-05 24.7 1.3 6.5e-05 22.9 1.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 GBG89871.1 - 3e-05 23.7 0.9 3e-05 23.7 0.9 2.1 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 GBG89871.1 - 0.00016 21.5 6.0 0.00016 21.5 6.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 GBG89871.1 - 0.0023 17.8 4.9 0.0023 17.8 4.9 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 GBG89871.1 - 0.0034 17.4 1.7 0.0034 17.4 1.7 2.2 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GBG89871.1 - 0.0054 16.3 4.3 0.0054 16.3 4.3 2.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GBG89871.1 - 0.0057 16.6 6.1 0.0057 16.6 6.1 2.3 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 GBG89871.1 - 0.25 11.4 3.7 1 9.4 3.7 2.2 1 0 0 1 1 1 0 Zinc-finger zf-UDP PF14569.6 GBG89871.1 - 0.47 10.6 12.3 0.91 9.7 3.1 3.3 2 0 0 2 2 2 0 Zinc-binding RING-finger rve PF00665.26 GBG89872.1 - 2.6e-15 56.7 0.0 8.3e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG89872.1 - 3.5e-15 55.9 0.2 3.5e-15 55.9 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG89872.1 - 0.013 15.7 0.3 0.034 14.4 0.3 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RIIa PF02197.17 GBG89873.1 - 5e-08 32.5 0.0 8.3e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_7 PF13499.6 GBG89874.1 - 2.6e-15 56.6 0.1 0.00023 21.5 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 GBG89874.1 - 5.5e-12 44.6 1.0 0.00029 20.5 0.1 5.6 7 0 0 7 7 7 3 EF-hand domain EF-hand_1 PF00036.32 GBG89874.1 - 1.5e-10 39.9 0.1 0.002 17.5 0.1 5.4 5 0 0 5 5 5 2 EF hand RIIa PF02197.17 GBG89874.1 - 3.2e-07 29.9 0.0 6.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_8 PF13833.6 GBG89874.1 - 3.2e-06 26.9 0.2 0.0023 17.7 0.0 4.5 4 2 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 GBG89874.1 - 0.0049 16.3 3.7 0.33 10.5 0.1 4.5 5 0 0 5 5 5 1 EF hand DUF5580 PF17743.1 GBG89874.1 - 0.12 10.9 0.3 0.2 10.2 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) YMF19 PF02326.15 GBG89875.1 - 0.1 13.4 2.1 2.3 9.1 0.0 2.7 2 1 0 2 2 2 0 Plant ATP synthase F0 DUF1582 PF07621.11 GBG89875.1 - 0.13 12.3 1.2 0.82 9.6 1.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1582) Amino_oxidase PF01593.24 GBG89876.1 - 3.8e-42 145.1 2.2 4.8e-41 141.5 0.6 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG89876.1 - 9.3e-16 57.8 1.6 1.3e-15 57.4 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG89876.1 - 1e-07 31.9 2.9 1e-07 31.9 2.9 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG89876.1 - 2e-07 30.5 1.3 4.3e-07 29.4 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GBG89876.1 - 4.2e-06 26.2 1.0 7.2e-06 25.5 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GBG89876.1 - 3.1e-05 22.9 0.2 4.4e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 GBG89876.1 - 4.3e-05 23.0 1.3 6.4e-05 22.5 1.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GBG89876.1 - 5.2e-05 22.6 0.2 9.1e-05 21.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GBG89876.1 - 9.9e-05 21.7 0.2 0.00021 20.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GBG89876.1 - 0.00013 21.2 0.6 0.0003 20.0 0.6 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 GBG89876.1 - 0.0041 16.2 0.2 0.0064 15.6 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 GBG89876.1 - 0.0094 16.5 0.2 0.02 15.4 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG89876.1 - 0.015 14.6 0.2 0.023 13.9 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GBG89876.1 - 0.054 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding PI3_PI4_kinase PF00454.27 GBG89877.1 - 1.1e-50 172.8 0.0 1.1e-50 172.8 0.0 3.0 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 GBG89877.1 - 7.9e-47 160.0 0.0 7.9e-47 160.0 0.0 2.9 2 1 0 2 2 2 1 NUC194 domain FATC PF02260.20 GBG89877.1 - 4.5e-10 39.2 0.8 1e-09 38.0 0.8 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 GBG89877.1 - 0.0067 16.6 6.6 2.6 8.6 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat TPR_14 PF13428.6 GBG89877.1 - 1.6 9.8 8.0 23 6.2 0.2 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 GBG89878.1 - 0.14 12.2 0.7 0.63 10.1 0.8 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RVT_1 PF00078.27 GBG89879.1 - 2.5e-30 105.6 0.0 5.5e-30 104.5 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89879.1 - 2.4e-23 82.1 0.0 4.9e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89879.1 - 1.3e-22 80.0 0.0 2.5e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89879.1 - 3.1e-07 30.2 0.0 2.8e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG89879.1 - 3.9e-07 30.5 0.0 2.1e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89879.1 - 7.2e-07 29.8 0.0 5.5e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG89879.1 - 0.0016 18.2 0.1 0.012 15.4 0.1 2.1 1 1 0 1 1 1 1 Aspartyl protease DUF4916 PF16262.5 GBG89879.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) DUF1492 PF07374.11 GBG89882.1 - 0.039 14.1 0.2 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Nop14 PF04147.12 GBG89884.1 - 4.5e-05 21.9 21.9 4.5e-05 21.9 21.9 1.9 2 0 0 2 2 2 1 Nop14-like family SAPS PF04499.15 GBG89884.1 - 0.0011 17.8 4.1 0.0015 17.4 4.1 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein HSP70 PF00012.20 GBG89884.1 - 0.045 11.9 5.1 0.052 11.7 5.1 1.2 1 0 0 1 1 1 0 Hsp70 protein Drc1-Sld2 PF11719.8 GBG89884.1 - 0.077 12.5 25.2 0.13 11.8 25.2 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein Spore_coat_CotO PF14153.6 GBG89884.1 - 1.8 8.4 31.6 0.067 13.1 21.1 2.1 2 0 0 2 2 2 0 Spore coat protein CotO SLC12 PF03522.15 GBG89884.1 - 4.9 6.1 8.1 7.5 5.5 8.1 1.4 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 GBG89884.1 - 7.1 6.4 28.2 0.22 11.3 19.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 GBG89884.1 - 7.5 5.7 11.3 13 4.9 11.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4360 PF14273.6 GBG89885.1 - 4.2e-35 121.2 0.0 4.9e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF1134 PF06577.12 GBG89886.1 - 3.1 7.5 4.6 2.9 7.6 3.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1134) AIP3 PF03915.13 GBG89887.1 - 0.0023 17.1 0.2 0.0023 17.1 0.2 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 Adaptin_binding PF10199.9 GBG89887.1 - 0.0085 16.7 3.4 0.0085 16.7 3.4 2.8 2 2 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DUF2576 PF10845.8 GBG89887.1 - 0.047 13.3 2.1 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) T6PP_N PF18572.1 GBG89887.1 - 0.058 13.2 1.6 0.71 9.7 0.1 2.7 3 0 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain SlyX PF04102.12 GBG89887.1 - 0.068 13.8 0.1 0.068 13.8 0.1 2.9 3 1 0 3 3 3 0 SlyX FUSC PF04632.12 GBG89887.1 - 0.1 11.2 1.1 0.16 10.5 1.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.15 GBG89887.1 - 0.16 11.8 1.6 0.49 10.2 0.0 2.5 3 0 0 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 GBG89887.1 - 0.9 8.8 9.1 3.2 7.0 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 GBG89887.1 - 3.7 8.1 6.8 0.65 10.5 0.6 2.7 2 1 0 2 2 2 0 Cell division protein ZapB RuvA_C PF07499.13 GBG89888.1 - 0.058 13.9 0.4 0.17 12.4 0.4 1.8 1 0 0 1 1 1 0 RuvA, C-terminal domain Tox-MPTase2 PF15638.6 GBG89888.1 - 0.12 12.1 0.3 1.5 8.5 0.0 2.4 3 0 0 3 3 3 0 Metallopeptidase toxin 2 zf-CCHC PF00098.23 GBG89889.1 - 5.4e-06 26.2 5.2 1e-05 25.4 5.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG89889.1 - 0.046 13.5 3.8 0.088 12.7 3.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG89889.1 - 1.7 8.7 9.0 0.15 12.0 4.0 1.8 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG89891.1 - 9e-29 100.6 0.1 1.4e-28 99.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG89891.1 - 4e-09 36.3 0.0 7.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89891.1 - 1.2e-07 32.3 0.0 2.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89891.1 - 4.1e-07 30.5 0.0 1.3e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG89891.1 - 0.00062 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease SAP PF02037.27 GBG89891.1 - 0.12 12.1 0.0 0.44 10.4 0.0 2.0 1 0 0 1 1 1 0 SAP domain FUSC PF04632.12 GBG89891.1 - 0.14 10.6 2.0 0.25 9.8 2.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF16 PF01519.16 GBG89891.1 - 0.17 12.4 0.8 0.61 10.6 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF16 Integrase_H2C2 PF17921.1 GBG89892.1 - 7.4e-19 67.6 2.3 9.6e-19 67.3 0.3 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG89892.1 - 2.2e-13 50.4 0.2 5.2e-13 49.2 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89892.1 - 5.9e-06 26.2 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG89892.1 - 0.012 15.8 0.0 0.044 14.0 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger Chromo PF00385.24 GBG89892.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 GBG89892.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF659 PF04937.15 GBG89893.1 - 2e-32 112.1 0.0 3.5e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG89893.1 - 8.6e-29 100.6 0.1 1.4e-28 100.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89893.1 - 3.9e-27 94.2 0.1 7.6e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89893.1 - 2.2e-23 82.5 0.1 4.2e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG89893.1 - 2e-13 50.6 0.0 8.4e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG89894.1 - 0.00025 20.6 0.0 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG89894.1 - 0.0063 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CENP-B_dimeris PF09026.10 GBG89894.1 - 0.075 13.4 6.8 0.15 12.4 6.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 GBG89894.1 - 8.8 4.3 7.5 13 3.8 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi RT_RNaseH PF17917.1 GBG89895.1 - 3e-22 78.9 2.5 1.1e-20 73.8 0.2 2.1 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89895.1 - 5.8e-12 45.5 0.2 3.2e-10 39.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG89895.1 - 0.1 12.2 13.4 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase IncFII_repA PF02387.15 GBG89895.1 - 4.3 6.5 9.0 6.6 5.9 9.0 1.2 1 0 0 1 1 1 0 IncFII RepA protein family PBP_sp32 PF07222.12 GBG89895.1 - 5.1 6.5 19.2 7.8 5.9 19.2 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 MAJIN PF15077.6 GBG89895.1 - 6.5 6.5 10.7 10 5.8 10.7 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein PSK PF06404.12 GBG89895.1 - 8 7.5 15.6 13 6.9 14.5 1.9 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) Integrase_H2C2 PF17921.1 GBG89896.1 - 4.8e-17 61.8 0.1 9.6e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89896.1 - 1.3e-12 47.9 0.0 2.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG89896.1 - 0.0072 16.3 2.0 0.017 15.0 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF4106 PF13388.6 GBG89896.1 - 0.027 13.7 7.4 0.046 13.0 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF3863 PF12979.7 GBG89896.1 - 0.032 13.1 1.2 0.047 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3863) ABC_membrane PF00664.23 GBG89900.1 - 1.5e-29 103.5 0.6 2.4e-29 102.8 0.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region rve PF00665.26 GBG89900.1 - 6.1e-13 49.0 0.0 2.6e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG89900.1 - 4.1e-12 46.0 0.1 1.1e-11 44.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG89900.1 - 1.2e-07 32.2 0.0 3.8e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG89900.1 - 7.7e-07 28.8 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG89900.1 - 2.8e-06 27.9 0.0 6.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG89900.1 - 0.017 15.4 0.0 0.049 13.9 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF4187 PF13821.6 GBG89900.1 - 0.021 14.6 0.8 0.069 12.9 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Asp_protease PF09668.10 GBG89900.1 - 0.09 12.6 1.3 0.18 11.6 1.3 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG89900.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease CPSF100_C PF13299.6 GBG89900.1 - 4.2 7.5 5.9 0.82 9.8 1.0 2.4 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal RT_RNaseH PF17917.1 GBG89902.1 - 5.3e-28 97.4 0.0 1.6e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89902.1 - 8.2e-28 96.4 0.0 2.3e-27 94.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89902.1 - 7.4e-16 58.3 0.0 1.9e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PCEMA1 PF07418.11 GBG89902.1 - 6.4 6.2 12.0 9.9 5.6 12.0 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 RVT_1 PF00078.27 GBG89903.1 - 1.7e-28 99.7 0.0 2.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89903.1 - 1.6e-26 92.3 0.1 3.2e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89903.1 - 1.7e-13 50.8 0.0 3.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89904.1 - 2.2e-29 101.8 0.6 1.2e-28 99.5 0.3 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89904.1 - 3e-22 78.5 0.0 6.7e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG89904.1 - 5.9e-05 23.3 0.6 0.066 13.5 0.1 3.0 2 1 0 2 2 2 2 Retrotransposon gag protein Asp_protease PF09668.10 GBG89904.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 GBG89904.1 - 0.014 15.2 0.8 0.014 15.2 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG89904.1 - 0.029 14.9 0.0 0.079 13.5 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG89904.1 - 0.035 14.4 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1664 PF07889.12 GBG89904.1 - 0.15 12.1 3.7 4.8 7.2 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Tricorn_C1 PF14684.6 GBG89904.1 - 0.5 10.5 2.0 24 5.1 0.0 3.4 3 0 0 3 3 3 0 Tricorn protease C1 domain zf-CCHC_3 PF13917.6 GBG89904.1 - 0.53 10.3 7.5 0.13 12.2 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF4396 PF14342.6 GBG89904.1 - 0.69 10.3 1.9 1.4 9.3 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) zf-CCHC PF00098.23 GBG89904.1 - 1.8 8.8 10.5 0.98 9.6 1.4 2.5 2 0 0 2 2 2 0 Zinc knuckle Trans_reg_C PF00486.28 GBG89905.1 - 0.015 15.4 0.2 0.042 13.9 0.2 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal zf-CCHC PF00098.23 GBG89905.1 - 0.025 14.6 0.6 0.049 13.7 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG89905.1 - 0.17 11.9 0.6 0.4 10.7 0.1 1.8 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG89906.1 - 3.2e-32 110.5 0.0 5.8e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89906.1 - 1.1e-28 99.6 0.3 2e-28 98.8 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG89906.1 - 1.9e-08 34.5 0.1 4.4e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG89907.1 - 1e-17 64.0 0.1 4.5e-17 61.9 0.2 2.1 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG89907.1 - 8.6e-07 29.2 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG89907.1 - 0.07 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger AAA_11 PF13086.6 GBG89907.1 - 0.32 10.7 11.6 0.32 10.8 0.4 2.5 2 0 0 2 2 2 0 AAA domain RT_RNaseH PF17917.1 GBG89910.1 - 5.7e-23 81.2 0.0 5e-22 78.2 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89910.1 - 2.9e-21 75.4 0.0 9.2e-21 73.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89910.1 - 3e-10 40.0 0.0 5.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S24 PF00717.23 GBG89911.1 - 1.4e-10 41.0 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 GBG89911.1 - 8.9e-09 35.2 0.1 1.4e-05 24.9 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 zf-RING_5 PF14634.6 GBG89912.1 - 4.5e-06 26.5 3.4 4.5e-06 26.5 3.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GBG89912.1 - 7e-05 23.1 4.9 7e-05 23.1 4.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 GBG89912.1 - 0.00026 20.9 2.9 0.00026 20.9 2.9 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG89912.1 - 0.00067 19.5 4.7 0.00067 19.5 4.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG89912.1 - 0.028 14.3 7.6 0.21 11.5 7.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_3 PF00933.21 GBG89913.1 - 6e-77 259.1 0.0 1.7e-76 257.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain HHV-1_VABD PF16852.5 GBG89913.1 - 0.0086 16.1 0.1 0.018 15.1 0.1 1.5 1 0 0 1 1 1 1 Herpes viral adaptor-to-host cellular mRNA binding domain Adeno_PIX PF03955.14 GBG89913.1 - 0.19 11.9 1.2 3.4 7.9 0.0 2.7 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) SKA2 PF16740.5 GBG89914.1 - 1.2e-08 34.7 0.4 1.4e-08 34.5 0.4 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 UPF0242 PF06785.11 GBG89914.1 - 0.038 14.1 0.4 0.051 13.7 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med21 PF11221.8 GBG89914.1 - 0.073 13.3 0.5 0.3 11.3 0.1 1.9 1 1 1 2 2 2 0 Subunit 21 of Mediator complex TIR PF01582.20 GBG89914.1 - 0.088 12.6 0.2 0.36 10.6 0.0 2.0 1 1 2 3 3 3 0 TIR domain HBS1_N PF08938.10 GBG89914.1 - 0.15 12.4 0.2 0.4 11.0 0.2 2.0 1 1 0 1 1 1 0 HBS1 N-terminus Ribosomal_L24e PF01246.20 GBG89915.1 - 5.1e-29 100.3 0.8 1.1e-28 99.3 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e M-inducer_phosp PF06617.13 GBG89915.1 - 0.013 14.8 0.9 0.013 14.8 0.9 1.7 1 1 1 2 2 2 0 M-phase inducer phosphatase DUF4897 PF16238.5 GBG89915.1 - 0.053 13.4 0.1 0.06 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) HDV_ag PF01517.18 GBG89915.1 - 1.8 8.3 9.7 4.7 7.0 2.3 2.1 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen Integrase_H2C2 PF17921.1 GBG89916.1 - 6.9e-14 51.7 0.1 2e-13 50.2 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89916.1 - 2e-12 47.4 0.0 4.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG89916.1 - 6.2e-11 42.7 0.1 2.3e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89916.1 - 1.9e-06 28.4 0.0 5.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG89916.1 - 0.0047 16.7 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG89916.1 - 0.006 16.9 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG89916.1 - 0.077 13.2 0.6 0.21 11.8 0.6 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG89917.1 - 1.8e-08 34.2 0.0 3.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Suf PF05843.14 GBG89917.1 - 0.029 14.4 0.8 0.05 13.6 0.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 GBG89917.1 - 1.5 7.5 3.4 2.3 6.9 3.4 1.2 1 0 0 1 1 1 0 Presenilin gag-asp_proteas PF13975.6 GBG89918.1 - 1.9e-06 28.4 0.1 4.4e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89918.1 - 4.9e-05 23.9 0.1 0.00011 22.7 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG89918.1 - 0.00038 20.2 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG89918.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG89918.1 - 0.072 13.2 1.9 0.12 12.4 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG89919.1 - 1.6e-08 34.3 0.0 2.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG89919.1 - 2.3e-06 28.1 0.0 6e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89919.1 - 0.00032 21.3 0.1 0.00066 20.3 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG89919.1 - 0.00036 20.3 0.1 0.00071 19.4 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG89919.1 - 0.03 14.1 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG89920.1 - 4.4e-14 52.8 0.7 1.4e-05 25.5 0.1 3.0 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89920.1 - 5e-11 43.1 1.0 0.0004 21.0 0.1 2.9 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.10 GBG89920.1 - 1.2e-07 31.5 0.4 0.0023 17.7 0.1 2.4 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG89920.1 - 1.2e-06 28.4 0.0 0.041 13.7 0.0 2.3 2 0 0 2 2 2 2 Retroviral aspartyl protease cNMP_binding PF00027.29 GBG89920.1 - 0.00014 21.9 0.1 0.64 10.1 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Peptidase_A3 PF02160.15 GBG89920.1 - 0.013 15.0 0.0 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) RHH_3 PF12651.7 GBG89920.1 - 0.23 11.5 1.3 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix domain zf-CCHC PF00098.23 GBG89921.1 - 1.2e-57 189.6 78.3 3.6e-06 26.8 1.9 11.1 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_3 PF13917.6 GBG89921.1 - 2.4e-20 72.2 45.6 0.013 15.5 0.6 11.0 3 3 8 11 11 11 10 Zinc knuckle zf-CCHC_2 PF13696.6 GBG89921.1 - 1.4e-15 56.7 87.2 0.0038 17.0 1.6 11.4 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_4 PF14392.6 GBG89921.1 - 2.6e-10 39.9 65.7 0.04 13.7 0.2 11.1 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_5 PF14787.6 GBG89921.1 - 1.8e-06 27.5 71.8 0.071 12.8 1.9 11.0 7 2 4 11 11 11 10 GAG-polyprotein viral zinc-finger YdaS_antitoxin PF15943.5 GBG89921.1 - 0.09 12.7 0.6 6.5 6.7 0.0 3.7 3 2 0 4 4 4 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Keratin_2_head PF16208.5 GBG89921.1 - 0.11 12.6 8.0 0.22 11.6 8.0 1.5 1 0 0 1 1 1 0 Keratin type II head PBP1_TM PF14812.6 GBG89923.1 - 0.95 9.9 6.2 1.6 9.2 6.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_20 PF00982.21 GBG89924.1 - 4.3e-166 553.3 0.0 5.6e-166 552.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GBG89924.1 - 7.3e-68 228.2 0.0 1.5e-67 227.1 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 GBG89924.1 - 0.00028 20.7 0.0 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RT_RNaseH_2 PF17919.1 GBG89925.1 - 1.2e-26 92.6 0.0 2e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89925.1 - 7.5e-26 90.5 0.0 1.6e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89925.1 - 0.0001 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG89925.1 - 0.0028 18.2 0.0 0.014 16.0 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG89925.1 - 0.023 14.5 0.1 0.037 13.8 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG89925.1 - 0.056 14.1 0.0 0.19 12.4 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease DUF4746 PF15928.5 GBG89925.1 - 4.4 6.6 15.5 0.79 9.1 11.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 GBG89925.1 - 5.9 5.0 17.5 8.6 4.4 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 GBG89925.1 - 9.9 5.0 18.3 15 4.4 18.3 1.1 1 0 0 1 1 1 0 Paf1 zf-CCHC PF00098.23 GBG89926.1 - 0.22 11.6 2.2 0.19 11.9 0.7 1.7 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG89927.1 - 1.1e-05 25.6 8.7 0.0014 18.9 1.0 3.5 3 0 0 3 3 3 2 Retrotransposon gag protein ABC_tran_Xtn PF12848.7 GBG89927.1 - 0.089 12.8 3.8 1.6 8.9 1.8 2.6 2 0 0 2 2 2 0 ABC transporter Methyltr_RsmB-F PF01189.17 GBG89927.1 - 0.13 11.9 0.7 0.24 11.0 0.7 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Exonuc_VII_L PF02601.15 GBG89927.1 - 1.5 8.3 7.7 2.6 7.5 7.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DPBB_1 PF03330.18 GBG89929.1 - 6.2e-19 68.1 2.4 6.3e-19 68.0 0.3 2.1 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG89929.1 - 1.1e-18 66.9 1.8 2.2e-18 66.0 1.8 1.5 1 0 0 1 1 1 1 Pollen allergen RT_RNaseH PF17917.1 GBG89930.1 - 2.6e-23 82.3 0.0 5.1e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89930.1 - 4e-21 74.9 0.0 7.8e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4207 PF13904.6 GBG89930.1 - 0.12 12.0 20.2 0.23 11.1 20.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) RT_RNaseH_2 PF17919.1 GBG89932.1 - 6.7e-22 77.4 0.0 1.6e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89932.1 - 4.1e-21 75.2 0.0 7.6e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89932.1 - 1.2e-17 63.7 0.1 2.2e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG89932.1 - 1.1e-14 54.5 0.1 2.6e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG89932.1 - 1.8e-07 31.0 0.0 3.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89932.1 - 5.7e-07 30.1 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89932.1 - 6.5e-05 23.4 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG89932.1 - 0.031 14.1 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease Tudor-knot PF11717.8 GBG89932.1 - 0.033 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Trypsin_2 PF13365.6 GBG89933.1 - 1.9e-25 90.5 10.8 1.8e-14 54.9 0.7 3.7 3 0 0 3 3 3 3 Trypsin-like peptidase domain Trypsin PF00089.26 GBG89933.1 - 7.4e-05 22.7 0.3 0.043 13.6 0.0 2.6 2 0 0 2 2 2 2 Trypsin Peptidase_S46 PF10459.9 GBG89933.1 - 0.021 13.5 0.4 0.42 9.2 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 7TM_GPCR_Sra PF02117.16 GBG89934.1 - 0.044 12.6 4.3 0.27 10.0 2.4 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sra Myb_DNA-bind_4 PF13837.6 GBG89936.1 - 3.3e-08 33.8 3.9 8.1e-08 32.5 2.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG89936.1 - 0.002 18.3 0.4 0.0043 17.3 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG89936.1 - 0.0089 16.3 0.6 0.08 13.3 0.2 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG89936.1 - 0.016 15.2 0.1 0.016 15.2 0.1 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG89936.1 - 0.021 15.0 0.3 0.058 13.6 0.3 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain TPR_7 PF13176.6 GBG89937.1 - 0.0092 15.9 0.0 0.04 14.0 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat DpnII-MboI PF18742.1 GBG89938.1 - 0.24 11.0 0.0 0.44 10.2 0.0 1.3 1 0 0 1 1 1 0 REase_DpnII-MboI RVT_1 PF00078.27 GBG89940.1 - 9.6e-23 80.9 0.1 1.5e-22 80.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG89940.1 - 1.9e-05 24.5 3.2 1.9e-05 24.5 3.2 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG89940.1 - 0.015 15.1 4.1 0.038 13.8 4.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 GBG89940.1 - 0.22 12.2 0.0 0.46 11.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease SDA1 PF05285.12 GBG89940.1 - 3.2 7.1 32.3 6.2 6.1 32.3 1.4 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG89940.1 - 4.4 7.0 25.6 9.1 5.9 25.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG89940.1 - 4.8 5.3 32.1 7.3 4.7 32.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG89940.1 - 6.9 4.8 22.9 11 4.2 22.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Copper-bind PF00127.20 GBG89941.1 - 2.2e-05 24.8 0.0 6.6e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Integrase_H2C2 PF17921.1 GBG89942.1 - 1.7e-17 63.3 0.0 3.5e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89942.1 - 7.4e-17 61.6 0.0 1.7e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DSPc PF00782.20 GBG89942.1 - 6.9e-13 48.6 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain rve_3 PF13683.6 GBG89942.1 - 0.0066 16.2 0.1 0.15 11.8 0.0 2.8 2 0 0 2 2 2 1 Integrase core domain SET PF00856.28 GBG89943.1 - 2.6e-20 73.5 0.4 2e-19 70.6 0.4 2.3 1 1 0 1 1 1 1 SET domain AWS PF17907.1 GBG89943.1 - 0.0015 18.5 12.6 0.0015 18.5 12.6 2.7 4 0 0 4 4 4 1 AWS domain zf-HC5HC2H PF13771.6 GBG89943.1 - 0.0021 18.3 10.4 0.0021 18.3 10.4 3.7 2 1 1 3 3 3 1 PHD-like zinc-binding domain HSP70 PF00012.20 GBG89944.1 - 3.1e-166 554.1 0.0 3.9e-166 553.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG89944.1 - 1.2e-09 37.5 0.3 1.7e-08 33.6 0.2 2.5 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG89944.1 - 0.00018 21.3 0.0 0.00056 19.7 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG89944.1 - 0.19 12.2 0.3 7.5 7.0 0.0 3.0 2 2 0 2 2 2 0 Cell division protein FtsA LEM PF03020.15 GBG89944.1 - 0.26 10.9 0.9 0.58 9.8 0.3 2.0 2 0 0 2 2 2 0 LEM domain HSP70 PF00012.20 GBG89945.1 - 2.1e-149 498.5 0.0 3.2e-149 497.9 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG89945.1 - 4.3e-07 29.1 0.4 1.6e-06 27.2 0.0 2.1 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG89945.1 - 0.013 15.3 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 GBG89946.1 - 4.2e-114 381.9 0.0 3.6e-54 184.0 0.1 3.0 3 0 0 3 3 3 3 Hsp70 protein FGGY_C PF02782.16 GBG89946.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain RT_RNaseH_2 PF17919.1 GBG89947.1 - 2.5e-32 110.9 0.0 4.5e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89947.1 - 1.6e-30 105.5 0.0 2.8e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89947.1 - 7.6e-07 28.9 0.1 1.1e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89948.1 - 5e-28 97.1 0.0 9.2e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89948.1 - 4.9e-26 91.1 0.0 8.3e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89948.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG89948.1 - 0.76 8.0 28.8 1.1 7.5 28.8 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG89948.1 - 1.1 8.5 41.0 1.8 7.8 41.0 1.2 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 GBG89948.1 - 1.2 7.7 31.9 1.8 7.1 31.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDHD PF02862.17 GBG89948.1 - 1.9 8.6 4.9 3.9 7.6 4.9 1.5 1 0 0 1 1 1 0 DDHD domain SDA1 PF05285.12 GBG89948.1 - 6.4 6.1 40.2 11 5.3 40.2 1.3 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG89948.1 - 8.2 5.9 19.3 12 5.3 19.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist VCBS PF13517.6 GBG89949.1 - 7.9e-11 42.4 6.0 1e-07 32.4 0.8 3.3 4 0 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GBG89949.1 - 3.9e-09 36.5 1.3 0.021 14.9 0.0 3.7 3 0 0 3 3 3 2 FG-GAP repeat TcdB_toxin_midN PF12256.8 GBG89949.1 - 0.00026 20.4 0.7 0.74 9.2 0.0 3.2 2 1 1 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region Dockerin_1 PF00404.18 GBG89949.1 - 0.0017 18.5 1.4 0.51 10.6 0.1 3.0 3 0 0 3 3 3 1 Dockerin type I domain PliI PF16743.5 GBG89949.1 - 0.11 12.2 0.0 12 5.7 0.0 3.1 3 0 0 3 3 3 0 Periplasmic lysozyme inhibitor of I-type lysozyme DUF3514 PF12027.8 GBG89949.1 - 0.21 11.2 0.0 0.31 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3514) EF-hand_5 PF13202.6 GBG89949.1 - 8.6 6.0 9.5 1 9.0 0.2 3.1 3 0 0 3 3 3 0 EF hand DUF659 PF04937.15 GBG89950.1 - 9.8e-61 204.1 0.0 1e-29 103.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) SNF2_N PF00176.23 GBG89950.1 - 1.2e-54 185.4 0.0 1.9e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GBG89950.1 - 1.2e-14 54.6 0.0 2.6e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG89950.1 - 2.5e-09 37.4 0.0 6.4e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dimer_Tnp_hAT PF05699.14 GBG89950.1 - 3.8e-05 23.4 0.2 9.3e-05 22.1 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SWI2_SNF2 PF18766.1 GBG89950.1 - 0.00074 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ADD_ATRX PF17981.1 GBG89950.1 - 0.0075 16.1 0.6 0.025 14.4 0.6 1.9 1 0 0 1 1 1 1 Cysteine Rich ADD domain ERCC3_RAD25_C PF16203.5 GBG89950.1 - 0.0091 15.2 0.0 0.054 12.7 0.0 2.1 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DALR_1 PF05746.15 GBG89950.1 - 0.11 12.6 1.4 0.39 10.9 1.4 1.9 1 0 0 1 1 1 0 DALR anticodon binding domain VHP PF02209.19 GBG89950.1 - 0.18 11.9 0.5 0.68 10.1 0.1 2.2 2 0 0 2 2 2 0 Villin headpiece domain Glyco_hydro_9 PF00759.19 GBG89951.1 - 7.8e-117 391.2 3.0 9.7e-117 390.9 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 RPS31 PF17067.5 GBG89952.1 - 0.00015 21.9 0.6 0.00015 21.9 0.6 2.5 2 1 1 3 3 3 1 Ribosomal protein S31e Thx PF17070.5 GBG89952.1 - 0.002 18.1 9.1 0.002 18.1 9.1 2.3 3 0 0 3 3 3 1 30S ribosomal protein Thx K_channel_TID PF07941.11 GBG89952.1 - 0.042 14.3 20.0 5.1 7.6 4.8 3.4 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Ribosomal_60s PF00428.19 GBG89952.1 - 0.52 10.9 19.2 2.7 8.6 7.3 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Molybdopterin_N PF18364.1 GBG89953.1 - 0.17 11.9 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain Ribosomal_L35Ae PF01247.18 GBG89954.1 - 5.9e-45 151.4 0.6 6.8e-45 151.2 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 GBG89954.1 - 0.0018 18.4 0.0 0.64 10.3 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Prothymosin PF03247.14 GBG89955.1 - 0.99 9.9 14.9 3.7 8.1 14.9 1.9 1 0 0 1 1 1 0 Prothymosin/parathymosin family SlyX PF04102.12 GBG89956.1 - 0.013 16.1 1.6 0.17 12.6 1.0 2.9 2 0 0 2 2 2 0 SlyX Spc7 PF08317.11 GBG89956.1 - 0.09 11.6 0.2 0.16 10.9 0.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 GBG89956.1 - 0.22 11.6 0.0 0.46 10.6 0.0 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 PKcGMP_CC PF16808.5 GBG89956.1 - 7.2 6.6 6.0 0.53 10.2 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RVT_1 PF00078.27 GBG89957.1 - 4.6e-29 101.5 0.1 8.3e-29 100.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89957.1 - 1.7e-20 72.9 0.0 6.4e-20 71.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89957.1 - 1.2e-19 70.5 0.0 3.3e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89957.1 - 4.8e-17 61.8 0.1 1.1e-16 60.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89957.1 - 3.2e-09 37.0 0.1 1.3e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG89958.1 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG89958.1 - 3e-12 46.8 0.0 7.8e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG89958.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) SurA_N_3 PF13624.6 GBG89958.1 - 0.14 11.9 1.6 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 SurA N-terminal domain RVT_1 PF00078.27 GBG89959.1 - 4e-29 101.7 0.0 5.8e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TrmB PF01978.19 GBG89959.1 - 0.085 12.8 0.0 0.79 9.6 0.0 2.3 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RT_RNaseH PF17917.1 GBG89961.1 - 4.1e-27 94.5 0.2 1.2e-26 93.0 0.2 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89961.1 - 1e-19 70.4 0.1 4.2e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89961.1 - 2.1e-17 62.9 0.1 4.3e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG89961.1 - 3e-12 46.6 0.2 5.5e-12 45.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG89961.1 - 6.3e-07 29.9 0.0 2.2e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89961.1 - 9.5e-05 23.0 0.0 0.00041 20.9 0.0 2.2 2 0 0 2 2 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG89961.1 - 0.0014 18.8 0.1 0.0045 17.2 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger DUF1758 PF05585.12 GBG89961.1 - 0.015 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF5095 PF17016.5 GBG89961.1 - 0.035 13.8 0.5 0.096 12.4 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Asp_protease PF09668.10 GBG89961.1 - 0.038 13.8 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease HepII_C PF18675.1 GBG89961.1 - 0.099 12.8 0.0 20 5.3 0.0 2.7 2 0 0 2 2 2 0 Heparinase II C-terminal domain RepB PF07506.11 GBG89961.1 - 0.17 11.9 5.6 0.056 13.5 2.1 2.0 2 0 0 2 2 2 0 RepB plasmid partitioning protein Rrn6 PF10214.9 GBG89961.1 - 0.33 9.4 7.0 0.58 8.6 7.0 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NAM-associated PF14303.6 GBG89961.1 - 1.2 9.8 6.0 3.2 8.5 6.0 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RVT_1 PF00078.27 GBG89962.1 - 1.2e-26 93.6 0.4 2.3e-26 92.7 0.4 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG89962.1 - 4.1e-15 55.6 0.6 2.4e-14 53.2 0.0 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG89962.1 - 2.6e-11 43.7 0.0 7.1e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF3417 PF11897.8 GBG89962.1 - 0.0095 16.4 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3417) zf-H2C2 PF09337.10 GBG89962.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG89962.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase STI1 PF17830.1 GBG89962.1 - 0.17 11.8 0.5 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 STI1 domain rve PF00665.26 GBG89963.1 - 1.7e-13 50.8 0.1 3.1e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain BAF250_C PF12031.8 GBG89963.1 - 0.02 14.2 0.1 0.051 12.9 0.1 1.7 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa Ribosomal_L18 PF17135.4 GBG89963.1 - 0.053 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Dynactin_p22 PF07426.11 GBG89963.1 - 0.075 12.9 3.0 3 7.7 0.1 2.5 2 0 0 2 2 2 0 Dynactin subunit p22 DUF4164 PF13747.6 GBG89963.1 - 0.086 13.1 8.8 0.44 10.9 8.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Noelin-1 PF12308.8 GBG89963.1 - 0.24 11.4 1.1 0.74 9.8 1.1 1.8 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF2203 PF09969.9 GBG89963.1 - 0.29 11.9 2.8 0.22 12.2 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2630 PF10944.8 GBG89963.1 - 2.3 8.8 6.2 2.9 8.4 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2630) NPV_P10 PF05531.12 GBG89963.1 - 4.4 7.8 5.2 19 5.8 3.2 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RT_RNaseH_2 PF17919.1 GBG89965.1 - 1.2e-33 115.1 0.0 2.1e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89965.1 - 3e-30 104.6 0.1 5.8e-30 103.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89965.1 - 7.1e-30 104.2 0.1 1.1e-29 103.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTRD1 PF17660.1 GBG89965.1 - 0.051 13.4 0.0 2.9 7.8 0.0 2.7 3 0 0 3 3 3 0 Bacterial tandem repeat domain 1 RVT_1 PF00078.27 GBG89967.1 - 4e-23 82.1 0.1 8.6e-23 81.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG89967.1 - 4e-07 30.6 0.0 8.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89967.1 - 1.6e-06 28.6 0.0 3.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG89967.1 - 5.3e-06 26.2 0.0 8.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG89967.1 - 8.2e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG89968.1 - 4.7e-28 98.2 0.1 8.4e-28 97.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG89968.1 - 4.1e-18 65.6 0.0 1.2e-17 64.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG89968.1 - 2.7e-11 43.4 0.0 5.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPO PF05929.11 GBG89968.1 - 0.18 11.4 0.1 0.45 10.1 0.0 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HalX PF08663.10 GBG89968.1 - 0.35 11.2 2.8 4.9 7.5 0.0 3.6 5 0 0 5 5 5 0 HalX domain rve PF00665.26 GBG89969.1 - 3.4e-16 59.5 0.0 7.4e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG89969.1 - 0.00055 19.7 0.1 0.0016 18.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) Chromo PF00385.24 GBG89969.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DAPDH_C PF16654.5 GBG89969.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain RVT_1 PF00078.27 GBG89970.1 - 2.2e-10 40.4 0.1 4.8e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG89970.1 - 0.0042 17.3 0.3 0.0042 17.3 0.3 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein Lipin_mid PF16876.5 GBG89970.1 - 0.045 13.9 0.5 0.31 11.2 0.0 2.4 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain gag-asp_proteas PF13975.6 GBG89971.1 - 7.3e-05 23.3 0.1 0.00017 22.1 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89971.1 - 0.0016 19.0 0.0 0.0035 18.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG89971.1 - 0.014 15.2 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG89971.1 - 0.049 13.7 2.3 0.09 12.9 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Beta_helix PF13229.6 GBG89972.1 - 0.0071 16.2 0.3 0.9 9.4 0.1 2.2 2 0 0 2 2 2 2 Right handed beta helix region Chlam_PMP PF02415.17 GBG89972.1 - 0.74 10.4 29.8 0.94 10.1 0.3 5.7 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chlam_PMP PF02415.17 GBG89973.1 - 1.6e-08 34.5 21.7 0.032 14.7 0.1 7.6 7 0 0 7 7 7 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 GBG89973.1 - 2e-06 27.7 1.2 6.7e-06 26.0 1.2 1.8 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG89973.1 - 0.048 12.9 0.3 0.28 10.4 0.2 1.9 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) DUF4407 PF14362.6 GBG89974.1 - 0.046 13.1 2.2 0.062 12.6 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PRIMA1 PF16101.5 GBG89975.1 - 5 7.2 10.5 32 4.6 9.8 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Chlam_PMP PF02415.17 GBG89976.1 - 0.046 14.2 32.2 2 9.1 0.0 7.4 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4957 PF16318.5 GBG89976.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4957) Chlam_PMP PF02415.17 GBG89977.1 - 0.23 12.0 27.0 3.3 8.4 0.0 7.1 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat LEA_1 PF03760.15 GBG89979.1 - 0.017 15.8 10.2 0.036 14.7 10.2 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Retrotrans_gag PF03732.17 GBG89979.1 - 0.023 14.9 4.2 0.025 14.9 0.1 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein Trypsin PF00089.26 GBG89980.1 - 6.2e-34 117.7 1.5 8.2e-34 117.3 1.5 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GBG89980.1 - 4.2e-06 27.7 0.4 7.1e-06 27.0 0.4 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GBG89981.1 - 6.3e-35 121.0 1.5 8e-35 120.6 1.5 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GBG89981.1 - 2.6e-06 28.4 0.4 6.4e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain ATP-synt_C PF00137.21 GBG89981.1 - 6.2 7.3 13.6 0.25 11.7 0.8 3.3 3 0 0 3 3 3 0 ATP synthase subunit C RVT_1 PF00078.27 GBG89983.1 - 3.4e-30 105.2 0.1 4.8e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG89983.1 - 2.2e-05 24.9 0.0 4.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG89983.1 - 9.7e-05 22.9 0.0 0.00024 21.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 GBG89983.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 GBG89983.1 - 0.039 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG89983.1 - 0.056 13.2 0.1 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG89984.1 - 2.1e-75 253.1 0.1 2.3e-28 99.2 0.0 3.3 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89984.1 - 3.8e-33 113.5 0.0 7.5e-16 58.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG89984.1 - 9.5e-17 60.9 0.7 5.6e-16 58.4 0.1 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG89984.1 - 6.5e-12 45.7 0.2 0.00034 20.9 0.0 3.8 3 1 1 4 4 4 3 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89984.1 - 5.8e-06 26.1 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89984.1 - 0.00027 21.5 0.0 0.00074 20.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89984.1 - 0.001 19.5 0.0 0.005 17.4 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF5095 PF17016.5 GBG89984.1 - 0.22 11.2 1.4 2.1 8.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) RVT_1 PF00078.27 GBG89986.1 - 4.4e-31 108.1 0.0 6.7e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CLIP1_ZNF PF16641.5 GBG89987.1 - 0.49 10.3 11.9 1.6 8.7 1.6 2.6 2 0 0 2 2 2 0 CLIP1 zinc knuckle Sec20 PF03908.13 GBG89988.1 - 0.00034 20.5 7.7 0.00063 19.6 1.2 3.3 2 2 2 4 4 4 1 Sec20 RPW8 PF05659.11 GBG89988.1 - 0.00045 19.9 6.5 0.022 14.5 1.5 3.0 2 1 1 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 EzrA PF06160.12 GBG89988.1 - 0.00065 18.0 3.0 0.00065 18.0 3.0 2.6 3 0 0 3 3 3 1 Septation ring formation regulator, EzrA Helo_like_N PF17111.5 GBG89988.1 - 0.0011 18.4 0.5 0.0011 18.4 0.5 1.7 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins V-SNARE_C PF12352.8 GBG89988.1 - 0.0037 17.5 1.1 0.0037 17.5 1.1 2.5 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Occludin_ELL PF07303.13 GBG89988.1 - 0.004 17.8 0.8 0.004 17.8 0.8 2.4 3 1 0 3 3 2 1 Occludin homology domain Globin PF00042.22 GBG89988.1 - 0.0042 17.6 1.2 0.83 10.2 0.2 2.7 2 1 0 2 2 2 1 Globin Prominin PF05478.11 GBG89988.1 - 0.0049 14.9 2.5 0.0049 14.9 2.5 2.0 2 0 0 2 2 2 1 Prominin Sigma70_ner PF04546.13 GBG89988.1 - 0.0089 15.9 4.6 0.064 13.1 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, non-essential region DUF948 PF06103.11 GBG89988.1 - 0.016 15.5 9.4 16 5.8 0.0 4.2 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1759 PF03564.15 GBG89988.1 - 0.059 13.3 3.2 0.34 10.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Rogdi_lz PF10259.9 GBG89988.1 - 0.06 12.8 1.1 6.7 6.1 0.1 2.1 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein Laminin_II PF06009.12 GBG89988.1 - 0.1 12.6 8.4 1.8 8.5 1.5 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF3970 PF13113.6 GBG89988.1 - 0.19 11.9 8.3 3.7 7.8 0.2 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF3970) TMPIT PF07851.13 GBG89988.1 - 0.21 10.8 8.9 0.37 10.0 3.1 2.0 2 0 0 2 2 2 0 TMPIT-like protein GCIP PF13324.6 GBG89988.1 - 0.22 11.1 5.2 1.4 8.5 0.5 2.1 1 1 0 2 2 2 0 Grap2 and cyclin-D-interacting Cob_adeno_trans PF01923.18 GBG89988.1 - 0.29 11.3 3.8 7.4 6.7 0.3 2.2 2 0 0 2 2 2 0 Cobalamin adenosyltransferase MCU PF04678.13 GBG89988.1 - 0.29 11.2 6.2 0.21 11.7 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter V-SNARE PF05008.15 GBG89988.1 - 0.4 11.1 8.4 0.27 11.6 3.7 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Baculo_PEP_C PF04513.12 GBG89988.1 - 0.51 10.4 5.6 5 7.2 0.4 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DegS PF05384.11 GBG89988.1 - 0.66 9.5 8.2 4.7 6.7 0.6 2.9 2 2 1 3 3 3 0 Sensor protein DegS Syntaxin_2 PF14523.6 GBG89988.1 - 0.7 10.3 11.8 1.2 9.6 1.4 3.0 1 1 1 3 3 3 0 Syntaxin-like protein JHD PF17811.1 GBG89988.1 - 0.74 10.4 4.3 2.2 8.9 0.4 2.3 2 0 0 2 2 2 0 Jumonji helical domain Fib_alpha PF08702.10 GBG89988.1 - 1.2 9.3 10.7 0.28 11.4 2.6 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family I_LWEQ PF01608.17 GBG89988.1 - 1.4 9.1 8.2 1.1 9.5 1.7 2.4 2 0 0 2 2 2 0 I/LWEQ domain IFT57 PF10498.9 GBG89988.1 - 1.5 7.7 11.8 0.29 10.0 3.6 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 V_ATPase_I PF01496.19 GBG89988.1 - 1.5 6.6 5.5 1.3 6.9 1.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Plasmid_RAQPRD PF09686.10 GBG89988.1 - 2.4 8.5 5.2 4.4 7.6 0.0 3.3 3 2 1 4 4 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF2408 PF10303.9 GBG89988.1 - 2.5 8.7 6.7 1.2 9.7 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF883 PF05957.13 GBG89988.1 - 3.4 8.3 7.2 5.7 7.6 0.4 3.0 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ING PF12998.7 GBG89988.1 - 4.2 8.0 7.0 3 8.5 1.7 2.6 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding PCRF PF03462.18 GBG89988.1 - 4.4 7.1 9.0 0.69 9.7 3.1 2.0 1 1 0 2 2 2 0 PCRF domain CCDC-167 PF15188.6 GBG89988.1 - 9.4 6.7 11.0 4.7 7.6 2.9 3.2 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DDE_Tnp_4 PF13359.6 GBG89990.1 - 7.6e-20 71.2 0.0 1.6e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG89990.1 - 1.8e-07 31.0 0.0 2.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG89990.1 - 0.0024 17.5 0.0 0.0055 16.4 0.0 1.6 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG89991.1 - 7.6e-08 32.6 0.7 2.8e-07 30.8 0.7 2.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG89991.1 - 0.0035 17.6 0.3 0.014 15.7 0.3 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like RT_RNaseH_2 PF17919.1 GBG89993.1 - 7.3e-28 96.5 0.0 1.1e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG89993.1 - 9.9e-28 96.5 0.0 1.6e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG89993.1 - 2.2e-08 33.9 0.1 3.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG89993.1 - 0.11 12.3 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Pkinase_Tyr PF07714.17 GBG89994.1 - 1.3e-28 100.1 0.0 2e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG89994.1 - 8.4e-25 87.6 0.0 1.4e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Saf_2TM PF18303.1 GBG89994.1 - 0.027 14.1 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Nitrate_red_gam PF02665.14 GBG89994.1 - 0.23 11.0 0.5 9.3 5.7 0.2 2.2 2 0 0 2 2 2 0 Nitrate reductase gamma subunit VEGFR-2_TMD PF17988.1 GBG89994.1 - 3.3 7.2 5.2 6.2 6.3 5.2 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain RVT_1 PF00078.27 GBG89995.1 - 4.6e-28 98.3 0.0 8e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG89995.1 - 2.9e-11 43.3 0.1 7.7e-09 35.5 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG89995.1 - 2.5e-09 37.0 0.0 7.2e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG89995.1 - 5.1e-08 33.4 0.0 1.1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG89995.1 - 4.1e-06 27.3 0.0 9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG89995.1 - 0.0018 18.1 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG89995.1 - 0.06 13.6 0.0 0.5 10.7 0.0 2.5 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase SlyX PF04102.12 GBG89995.1 - 0.35 11.5 0.1 0.35 11.5 0.1 4.1 3 1 1 4 4 4 0 SlyX Cofilin_ADF PF00241.20 GBG89996.1 - 1.4e-35 121.7 0.1 1.6e-35 121.6 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Na_trans_assoc PF06512.13 GBG89997.1 - 1.4 9.2 10.9 1.6 8.9 10.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG89997.1 - 9.6 5.5 18.6 12 5.3 18.6 1.1 1 0 0 1 1 1 0 SDA1 NADH-u_ox-rdase PF10785.9 GBG89999.1 - 4.8e-07 30.4 0.0 7.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit MgtE_N PF03448.17 GBG89999.1 - 6.9e-07 29.8 17.2 0.00034 21.2 7.5 2.1 1 1 1 2 2 2 2 MgtE intracellular N domain DUF481 PF04338.12 GBG89999.1 - 0.0067 16.5 1.5 0.14 12.2 0.4 2.0 1 1 1 2 2 2 2 Protein of unknown function, DUF481 TOBE PF03459.17 GBG89999.1 - 0.013 15.8 11.7 0.014 15.7 1.6 3.1 1 1 2 3 3 3 0 TOBE domain Rad50_zn_hook PF04423.14 GBG89999.1 - 0.029 14.2 4.1 18 5.3 0.3 3.9 1 1 4 5 5 5 0 Rad50 zinc hook motif DUF2807 PF10988.8 GBG89999.1 - 0.037 13.8 3.0 0.056 13.2 3.0 1.2 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Glyco_hydro_2 PF00703.21 GBG89999.1 - 0.14 12.8 6.6 3.5 8.4 1.5 2.8 1 1 1 2 2 2 0 Glycosyl hydrolases family 2 Gp23 PF07068.11 GBG89999.1 - 0.73 8.5 4.2 1 8.0 4.2 1.2 1 0 0 1 1 1 0 Major capsid protein Gp23 CopB PF05275.11 GBG89999.1 - 0.83 9.2 7.2 3.8 7.0 2.0 2.2 1 1 1 2 2 2 0 Copper resistance protein B precursor (CopB) DUF5132 PF17195.4 GBG89999.1 - 1.1 9.4 49.4 0.36 11.0 3.1 8.2 1 1 2 3 3 2 0 Protein of unknown function (DUF5132) Desulfoferrodox PF01880.18 GBG89999.1 - 1.3 9.6 2.6 71 4.1 2.6 2.5 1 1 0 1 1 1 0 Desulfoferrodoxin Ribosomal_L37 PF08561.10 GBG89999.1 - 6.9 7.2 16.3 8.3 7.0 1.9 2.9 1 1 2 3 3 3 0 Mitochondrial ribosomal protein L37 DNA_binding_1 PF01035.20 GBG90000.1 - 4e-25 87.7 0.2 9.6e-25 86.5 0.2 1.7 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain RT_RNaseH PF17917.1 GBG90001.1 - 1.3e-20 73.6 0.0 2.7e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90001.1 - 1.9e-19 69.6 0.0 3.7e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90001.1 - 1.5e-15 57.5 0.0 3.2e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG90001.1 - 1.7e-15 56.9 0.2 5.7e-15 55.2 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG90001.1 - 0.011 16.0 0.2 0.026 14.7 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 GBG90001.1 - 0.016 14.9 0.0 0.075 12.8 0.0 2.2 1 0 0 1 1 1 0 Integrase core domain CorA PF01544.18 GBG90002.1 - 1.3e-05 24.7 0.6 1.3e-05 24.7 0.6 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF4692 PF15763.5 GBG90002.1 - 0.013 16.0 1.0 0.026 15.0 1.0 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SR-25 PF10500.9 GBG90002.1 - 0.26 10.9 8.0 0.57 9.8 8.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 GBG90003.1 - 8.5e-10 38.5 0.2 1.3e-09 37.9 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG90003.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TPR_2 PF07719.17 GBG90004.1 - 6.1e-41 135.2 13.9 3.6e-06 26.7 0.0 10.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 GBG90004.1 - 1.9e-40 135.0 12.1 2e-08 33.7 0.1 9.2 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 GBG90004.1 - 8.5e-29 97.3 8.2 0.0001 22.2 0.0 8.6 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 GBG90004.1 - 1.9e-26 91.4 15.7 0.0012 18.5 0.0 9.6 6 2 4 10 10 10 6 TPR repeat TPR_12 PF13424.6 GBG90004.1 - 5.1e-21 74.8 18.6 2.6e-05 24.4 0.2 7.6 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 GBG90004.1 - 4.9e-20 71.8 9.1 0.00011 22.7 0.0 7.2 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 GBG90004.1 - 8e-20 69.8 14.6 0.0041 17.8 0.0 9.8 5 4 6 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 GBG90004.1 - 8.1e-20 69.3 5.9 0.08 13.0 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 GBG90004.1 - 9.3e-20 71.0 2.0 0.0024 18.5 0.0 6.7 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 GBG90004.1 - 6.8e-17 61.4 2.5 0.00067 19.8 0.0 5.8 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 GBG90004.1 - 1.9e-16 59.1 8.1 0.074 13.5 0.1 9.2 8 2 1 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 GBG90004.1 - 1.1e-14 54.0 13.6 0.22 12.3 0.1 9.5 11 0 0 11 11 10 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG90004.1 - 5.9e-14 52.1 8.8 0.00038 20.6 0.1 5.9 2 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GBG90004.1 - 1.1e-05 25.1 24.0 1.7 8.6 0.2 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_15 PF13429.6 GBG90004.1 - 1.1e-05 24.8 5.7 0.11 11.7 0.2 4.2 2 1 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 GBG90004.1 - 1.4e-05 25.6 2.3 0.057 13.9 0.2 4.1 3 1 1 4 4 4 1 Bacterial transcriptional activator domain ChAPs PF09295.10 GBG90004.1 - 0.00067 18.8 0.0 0.074 12.0 0.0 2.6 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 GBG90004.1 - 0.0031 17.5 2.7 23 5.2 0.0 5.2 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 GBG90004.1 - 0.0043 17.5 7.3 33 5.5 0.3 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 GBG90004.1 - 0.0056 16.7 1.5 6.7 6.8 0.2 3.4 3 0 0 3 3 3 1 Putative TPR-like repeat TPR_MalT PF17874.1 GBG90004.1 - 0.0096 15.3 5.1 1.4 8.2 2.7 3.1 2 1 0 2 2 2 1 MalT-like TPR region NARP1 PF12569.8 GBG90004.1 - 0.013 14.5 1.0 6.5 5.5 0.0 3.2 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 DUF2225 PF09986.9 GBG90004.1 - 0.078 12.7 1.3 4.6 6.9 0.3 3.0 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) CM_1 PF07736.11 GBG90004.1 - 0.095 13.1 0.4 6.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Chorismate mutase type I RT_RNaseH_2 PF17919.1 GBG90005.1 - 2.5e-19 69.2 0.0 4.4e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90005.1 - 3.8e-18 65.8 0.1 5.8e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG90005.1 - 3.9e-07 30.3 0.0 7.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG90005.1 - 3.2 7.1 23.7 5.1 6.4 23.7 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG90005.1 - 4 6.7 25.8 6.2 6.0 25.8 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG90005.1 - 5.2 5.2 18.8 8.7 4.5 18.8 1.3 1 0 0 1 1 1 0 CDC45-like protein ATE_N PF04376.13 GBG90006.1 - 0.018 15.4 0.2 0.32 11.4 0.0 2.4 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus zf-CCHC PF00098.23 GBG90006.1 - 0.054 13.6 1.9 0.054 13.6 1.9 1.7 2 0 0 2 2 2 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG90006.1 - 0.062 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like LRR_4 PF12799.7 GBG90007.1 - 0.0054 17.1 0.8 1.1 9.8 0.0 3.6 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) IL3 PF02059.15 GBG90007.1 - 0.18 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin-3 RT_RNaseH_2 PF17919.1 GBG90008.1 - 1.7e-33 114.6 0.0 4.7e-17 61.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90008.1 - 2.5e-25 88.8 0.0 5.6e-25 87.7 0.0 1.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90008.1 - 4.9e-23 81.8 0.0 8.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG90009.1 - 8e-19 67.9 0.0 4.2e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90009.1 - 1.5e-17 63.5 0.0 3.9e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90009.1 - 4.5e-10 39.4 0.0 7.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90009.1 - 0.024 14.8 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain DUF659 PF04937.15 GBG90010.1 - 3e-21 75.9 0.1 6e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) TYA PF01021.19 GBG90010.1 - 0.054 13.8 1.6 2.7 8.4 0.0 2.6 2 0 0 2 2 2 0 TYA transposon protein RVT_1 PF00078.27 GBG90012.1 - 5.3e-28 98.1 0.4 8.3e-28 97.4 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90012.1 - 9.2e-28 96.2 0.0 1.1e-13 51.1 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90012.1 - 4.2e-16 59.1 0.0 1e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4628 PF15429.6 GBG90012.1 - 0.26 10.9 1.6 0.39 10.4 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Tubulin PF00091.25 GBG90013.1 - 1.3e-69 234.4 0.0 2.1e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG90013.1 - 3.6e-41 140.3 0.3 5.4e-41 139.7 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GBG90013.1 - 0.00043 20.6 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 GBG90013.1 - 0.00071 18.9 0.2 0.0018 17.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 GBG90013.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF659 PF04937.15 GBG90014.1 - 3.3e-32 111.4 0.1 5e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Tubulin PF00091.25 GBG90015.1 - 1.3e-69 234.4 0.0 2.1e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG90015.1 - 3.6e-41 140.3 0.3 5.4e-41 139.7 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GBG90015.1 - 0.00038 20.8 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 GBG90015.1 - 0.00071 18.9 0.2 0.0018 17.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 GBG90015.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain zf-CCHC PF00098.23 GBG90016.1 - 2.1e-06 27.5 2.6 2.1e-06 27.5 2.6 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG90016.1 - 0.058 13.1 0.8 0.11 12.2 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG90016.1 - 0.059 13.3 1.0 0.15 12.1 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle Connexin PF00029.19 GBG90016.1 - 0.091 12.5 2.5 0.16 11.7 2.5 1.3 1 0 0 1 1 1 0 Connexin SOG2 PF10428.9 GBG90016.1 - 0.11 11.7 2.1 0.16 11.1 2.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DDHD PF02862.17 GBG90016.1 - 0.12 12.5 1.2 0.15 12.2 1.2 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 GBG90016.1 - 1.6 7.4 5.7 1.9 7.2 5.7 1.2 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 GBG90016.1 - 2.7 6.0 10.2 3.5 5.6 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RR_TM4-6 PF06459.12 GBG90016.1 - 3.1 7.5 11.5 2 8.2 9.8 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 GBG90016.1 - 4.3 7.1 10.4 7.2 6.3 10.4 1.4 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 GBG90017.1 - 9.9e-28 97.2 0.1 1.5e-27 96.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90017.1 - 1.1e-09 38.2 0.0 4.3e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG90017.1 - 1.8e-06 28.5 0.0 3.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90017.1 - 2.6e-05 24.7 0.0 5.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG90017.1 - 9.8e-05 22.1 0.0 0.00028 20.6 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG90017.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG90018.1 - 0.018 15.3 5.9 0.057 13.7 0.0 4.0 4 2 1 5 5 5 0 Retrotransposon gag protein ERM PF00769.19 GBG90018.1 - 0.084 12.7 19.6 0.16 11.8 19.6 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family RNR_Alpha PF17975.1 GBG90018.1 - 0.18 12.3 2.1 2.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain TMF_TATA_bd PF12325.8 GBG90018.1 - 0.48 10.7 11.6 0.25 11.6 0.6 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding PIEZO PF15917.5 GBG90018.1 - 1.9 7.9 8.2 1.2 8.6 6.2 1.7 2 0 0 2 2 2 0 Piezo STAG PF08514.11 GBG90018.1 - 5.8 6.9 6.6 1.8 8.5 0.2 2.5 2 0 0 2 2 2 0 STAG domain Integrase_H2C2 PF17921.1 GBG90019.1 - 7.3e-11 42.0 0.1 2.2e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG90019.1 - 1.1e-07 32.0 0.0 3.7e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG90019.1 - 5.2e-06 26.9 0.0 1.9e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90019.1 - 2.4e-05 24.9 0.0 0.0001 22.9 0.0 2.1 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG90019.1 - 4.5e-05 23.2 0.0 0.00035 20.3 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG90019.1 - 0.00035 20.4 0.0 0.00064 19.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 GBG90019.1 - 0.0016 18.2 0.0 0.0086 15.9 0.0 2.1 1 1 0 1 1 1 1 Aspartyl protease TFIIA PF03153.13 GBG90019.1 - 7.2 6.5 19.3 13 5.7 19.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HSP70 PF00012.20 GBG90020.1 - 5.3e-162 540.1 0.0 6.3e-162 539.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG90020.1 - 1.3e-16 60.4 0.1 5.9e-16 58.2 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GBG90020.1 - 0.0031 17.9 0.4 3.5 8.1 0.0 3.3 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.18 GBG90020.1 - 0.013 14.8 0.1 0.14 11.4 0.1 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 GBG90020.1 - 0.081 12.2 1.0 9.9 5.3 0.1 2.4 1 1 1 2 2 2 0 StbA protein BACON PF13004.7 GBG90020.1 - 0.11 12.5 1.2 0.83 9.7 1.2 2.3 1 1 0 1 1 1 0 Putative binding domain, N-terminal RVT_1 PF00078.27 GBG90021.1 - 2e-30 105.9 0.1 4.1e-30 104.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90021.1 - 1.4e-25 89.2 0.0 4.3e-25 87.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90021.1 - 2.8e-24 85.4 0.0 6.1e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90021.1 - 1.9e-18 66.3 0.4 3.6e-18 65.4 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90021.1 - 3e-14 53.2 0.0 6.1e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90021.1 - 2.1e-05 24.6 0.1 8.1e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 H2C2 zinc finger RVP_2 PF08284.11 GBG90021.1 - 0.013 15.3 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF5338 PF17273.2 GBG90021.1 - 0.064 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Asn_synthase PF00733.21 GBG90022.1 - 1.8e-18 67.3 1.9 3.9e-09 36.7 1.0 3.3 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 GBG90022.1 - 6.4e-07 29.3 0.0 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase domain GATase_6 PF13522.6 GBG90022.1 - 0.0096 16.1 0.0 0.16 12.2 0.0 2.5 1 1 0 1 1 1 1 Glutamine amidotransferase domain TruB_N PF01509.18 GBG90023.1 - 9.5e-54 181.8 0.0 1.6e-53 181.1 0.0 1.4 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GBG90023.1 - 6.4e-09 35.8 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain RVT_1 PF00078.27 GBG90024.1 - 2.7e-33 115.3 0.1 4.7e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90024.1 - 5.6e-29 100.1 0.0 1.4e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90024.1 - 2.3e-25 88.9 0.0 5e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90024.1 - 1e-18 67.7 0.0 2.5e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG90024.1 - 1.9e-12 47.1 0.0 4.7e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG90024.1 - 0.0028 17.3 2.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 2 Phage capsid scaffolding protein (GPO) serine peptidase zf-H2C2 PF09337.10 GBG90024.1 - 0.0062 16.7 0.0 0.024 14.8 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger tRNA_lig_CPD PF08302.11 GBG90024.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Ribosomal_L18 PF17135.4 GBG90025.1 - 1.9e-58 196.9 0.1 2.3e-58 196.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e DDE_Tnp_4 PF13359.6 GBG90026.1 - 9.3e-15 54.6 0.2 3.6e-06 26.7 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90026.1 - 4.6e-09 36.2 0.0 0.001 18.7 0.0 2.2 1 1 1 2 2 2 2 Plant transposon protein NPR3 PF03666.13 GBG90027.1 - 0.51 9.1 2.1 0.85 8.3 2.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Goodbye PF17109.5 GBG90028.1 - 0.32 11.4 3.5 6 7.3 0.2 3.0 1 1 2 3 3 3 0 fungal STAND N-terminal Goodbye domain Arm PF00514.23 GBG90029.1 - 9.7e-35 117.5 7.9 4e-10 39.4 0.2 6.6 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat U-box PF04564.15 GBG90029.1 - 4.6e-21 74.8 0.0 2.2e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 U-box domain HEAT_2 PF13646.6 GBG90029.1 - 1.4e-05 25.4 9.8 0.00043 20.6 0.6 3.7 1 1 3 4 4 4 2 HEAT repeats KAP PF05804.12 GBG90029.1 - 4e-05 22.0 0.0 0.0068 14.6 0.0 2.0 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) zf-RING_UBOX PF13445.6 GBG90029.1 - 0.00012 22.0 0.9 0.00038 20.4 0.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GBG90029.1 - 0.00084 19.5 0.0 0.0021 18.2 0.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 GBG90029.1 - 0.00097 18.9 0.3 0.013 15.3 0.1 2.5 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit Arm_2 PF04826.13 GBG90029.1 - 0.0031 17.0 0.0 0.0077 15.7 0.0 1.6 1 1 0 1 1 1 1 Armadillo-like zf-C3HC4_2 PF13923.6 GBG90029.1 - 0.0054 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HEAT PF02985.22 GBG90029.1 - 0.0096 16.1 4.0 0.72 10.3 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat RPW8 PF05659.11 GBG90029.1 - 0.015 15.0 1.9 0.031 14.0 0.2 2.0 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3361 PF11841.8 GBG90029.1 - 0.021 14.8 0.6 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) zf-RING_2 PF13639.6 GBG90029.1 - 0.042 14.2 0.1 0.12 12.7 0.1 1.9 1 0 0 1 1 1 0 Ring finger domain Neurochondrin PF05536.11 GBG90029.1 - 0.097 11.0 0.7 0.66 8.3 0.1 2.0 2 0 0 2 2 2 0 Neurochondrin Cnd1 PF12717.7 GBG90029.1 - 0.11 12.5 0.1 4 7.5 0.0 2.7 1 1 2 3 3 3 0 non-SMC mitotic condensation complex subunit 1 zf-rbx1 PF12678.7 GBG90029.1 - 0.19 12.0 0.1 0.5 10.7 0.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rib_5-P_isom_A PF06026.14 GBG90031.1 - 1.4e-62 210.3 0.1 3e-62 209.3 0.0 1.6 2 0 0 2 2 2 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 GBG90031.1 - 0.00051 20.0 0.3 0.013 15.5 0.2 2.4 2 0 0 2 2 2 1 DeoR C terminal sensor domain Pro_isomerase PF00160.21 GBG90032.1 - 1.5e-48 165.1 0.1 1.7e-48 164.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RT_RNaseH_2 PF17919.1 GBG90033.1 - 2.7e-28 97.9 0.0 4.6e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90033.1 - 5.4e-26 90.9 0.0 8.4e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90033.1 - 1.6e-14 54.0 0.1 2.4e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG90033.1 - 0.074 12.5 19.5 0.1 12.0 19.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG90033.1 - 1.6 7.0 11.3 2.1 6.6 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG90033.1 - 2.2 6.4 21.2 3 5.9 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 GBG90033.1 - 4.4 7.5 16.0 7.1 6.9 16.0 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 GBG90033.1 - 8.4 5.6 20.7 13 5.0 20.7 1.2 1 0 0 1 1 1 0 BUD22 zf-RING_2 PF13639.6 GBG90037.1 - 2.2e-13 50.3 3.8 2.2e-13 50.3 3.8 2.3 2 1 1 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 GBG90037.1 - 1.1e-10 41.1 1.2 1.1e-10 41.1 1.2 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GBG90037.1 - 6.1e-09 35.6 4.8 6.1e-09 35.6 4.8 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG90037.1 - 9.6e-09 35.4 6.0 9.6e-09 35.4 6.0 2.3 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-RanBP PF00641.18 GBG90037.1 - 4.6e-07 29.0 0.1 4.6e-07 29.0 0.1 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-RING_UBOX PF13445.6 GBG90037.1 - 2e-06 27.7 0.5 6.8e-06 26.0 0.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GBG90037.1 - 7.2e-06 26.0 1.1 7.2e-06 26.0 1.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 GBG90037.1 - 1e-05 25.3 3.8 1e-05 25.3 3.8 2.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG90037.1 - 3.8e-05 23.6 2.2 3.8e-05 23.6 2.2 2.3 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GBG90037.1 - 5.6e-05 22.9 3.0 5.6e-05 22.9 3.0 2.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG90037.1 - 0.00033 20.5 3.2 0.00033 20.5 3.2 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 GBG90037.1 - 0.00038 20.0 3.9 0.00038 20.0 3.9 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 GBG90037.1 - 0.025 14.5 1.2 0.025 14.5 1.2 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_16 PF17034.5 GBG90037.1 - 0.03 14.5 0.2 0.03 14.5 0.2 1.8 2 0 0 2 2 2 0 Zinc-ribbon like family RecR PF02132.15 GBG90037.1 - 0.14 11.8 9.4 2.3 7.9 2.7 3.3 3 0 0 3 3 3 0 RecR protein Rick_17kDa_Anti PF05433.15 GBG90037.1 - 0.28 11.1 19.7 0.12 12.2 14.8 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain FANCL_C PF11793.8 GBG90037.1 - 0.65 10.2 10.1 0.12 12.6 4.0 2.6 2 1 0 2 2 1 0 FANCL C-terminal domain Gly-zipper_YMGG PF13441.6 GBG90037.1 - 0.69 9.7 25.1 3.3 7.5 22.0 2.6 1 1 1 2 2 2 0 YMGG-like Gly-zipper DUF5518 PF17647.1 GBG90037.1 - 0.74 10.0 14.7 1.8 8.7 1.4 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5518) zf-C3H2C3 PF17122.5 GBG90037.1 - 2.2 8.4 8.6 0.12 12.4 2.2 2.1 2 0 0 2 2 2 0 Zinc-finger PHD PF00628.29 GBG90037.1 - 4.7 7.2 15.3 0.38 10.7 4.7 3.0 2 1 1 3 3 3 0 PHD-finger RINGv PF12906.7 GBG90037.1 - 4.8 7.4 9.7 0.51 10.5 5.1 1.9 2 0 0 2 2 1 0 RING-variant domain DUF1269 PF06897.12 GBG90037.1 - 8.9 6.7 14.4 0.66 10.3 7.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) SPATA19 PF15212.6 GBG90038.1 - 0.0034 17.6 0.1 0.71 10.1 0.0 2.5 2 0 0 2 2 2 2 Spermatogenesis-associated protein 19, mitochondrial RVT_1 PF00078.27 GBG90039.1 - 7.4e-27 94.3 0.0 1.3e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90039.1 - 4.9e-20 71.4 0.2 1.7e-19 69.6 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90039.1 - 7.4e-11 42.3 0.1 2.3e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90039.1 - 3.1e-09 37.1 0.0 1.1e-08 35.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG90039.1 - 2.2e-07 31.4 0.0 8.3e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90039.1 - 6.8e-06 26.6 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG90039.1 - 7.3e-05 22.6 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG90039.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG90039.1 - 0.0031 17.5 0.0 0.0099 15.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG90039.1 - 0.0068 16.7 3.1 0.17 12.1 0.0 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG90042.1 - 1e-13 51.1 0.6 2.2e-13 50.1 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG90042.1 - 0.31 11.3 0.9 0.66 10.2 0.9 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Pkinase PF00069.25 GBG90043.1 - 1.7e-22 80.0 0.0 5.3e-22 78.4 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain DUF2433 PF10360.9 GBG90043.1 - 0.26 11.4 3.9 4.4 7.4 0.3 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) zf-CCHC PF00098.23 GBG90044.1 - 2.6e-06 27.3 3.4 2.6e-06 27.3 3.4 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG90044.1 - 0.29 10.9 0.9 0.68 9.7 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Agenet PF05641.12 GBG90047.1 - 7.1e-12 45.6 6.2 1.1e-10 41.8 0.4 2.8 2 0 0 2 2 2 2 Agenet domain RVT_1 PF00078.27 GBG90048.1 - 6.1e-37 127.3 0.0 1e-36 126.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG90049.1 - 7.5e-05 23.4 5.7 9e-05 23.1 3.2 2.5 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase G10 PF01125.17 GBG90049.1 - 0.0073 16.1 0.6 0.013 15.3 0.6 1.3 1 0 0 1 1 1 1 G10 protein Phage_Gp19 PF09355.10 GBG90050.1 - 0.023 15.1 0.4 1.1 9.8 0.1 2.1 1 1 1 2 2 2 0 Phage protein Gp19/Gp15/Gp42 GIY-YIG PF01541.24 GBG90051.1 - 0.0034 17.6 0.0 0.0078 16.5 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain gag-asp_proteas PF13975.6 GBG90052.1 - 0.00036 21.0 0.0 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG90052.1 - 0.0006 20.1 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90052.1 - 0.001 19.7 0.0 0.0051 17.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 GBG90053.1 - 3.3e-35 121.6 0.1 2.7e-34 118.7 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90053.1 - 1.3e-08 34.8 0.0 6.4e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase BAF1_ABF1 PF04684.13 GBG90053.1 - 10 5.1 15.3 15 4.5 15.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor rve PF00665.26 GBG90054.1 - 2.9e-11 43.6 0.0 5.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG90054.1 - 1.5e-10 41.0 0.2 3.2e-10 40.0 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG90054.1 - 0.00058 20.0 0.2 0.0011 19.1 0.2 1.5 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG90055.1 - 8.4e-07 29.5 0.1 2.3e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90055.1 - 0.0004 21.0 0.1 0.0012 19.5 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG90055.1 - 0.0036 17.1 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG90055.1 - 0.039 14.0 1.8 0.087 12.9 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 GBG90055.1 - 0.042 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG90055.1 - 0.13 12.0 0.2 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-FCS PF06467.14 GBG90056.1 - 0.062 13.2 0.5 0.15 12.1 0.5 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Pep_deformylase PF01327.21 GBG90056.1 - 0.16 11.6 1.7 0.29 10.7 1.7 1.3 1 0 0 1 1 1 0 Polypeptide deformylase Ribosomal_60s PF00428.19 GBG90056.1 - 2 9.1 11.2 8.7 7.0 11.2 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein RT_RNaseH PF17917.1 GBG90057.1 - 1.5e-21 76.7 0.0 3.2e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90057.1 - 2.6e-21 75.5 0.0 5e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90057.1 - 5.2e-06 26.1 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SRP-alpha_N PF04086.13 GBG90057.1 - 2.9 7.7 11.2 6 6.7 11.2 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Folate_carrier PF01770.18 GBG90059.1 - 0.2 10.3 0.8 0.3 9.8 0.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier Neisseria_TspB PF05616.13 GBG90059.1 - 0.29 9.6 3.6 0.45 8.9 3.6 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DDHD PF02862.17 GBG90059.1 - 0.52 10.4 5.7 0.95 9.6 2.9 2.2 2 0 0 2 2 2 0 DDHD domain Eapp_C PF10238.9 GBG90059.1 - 3.8 7.6 7.4 1.3 9.1 2.7 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Connexin PF00029.19 GBG90059.1 - 5.8 6.6 11.5 0.29 10.9 4.9 1.9 2 0 0 2 2 2 0 Connexin Presenilin PF01080.17 GBG90059.1 - 6.9 5.3 9.1 2.3 6.9 4.7 1.9 2 0 0 2 2 2 0 Presenilin SAPS PF04499.15 GBG90060.1 - 0.21 10.3 1.4 0.33 9.7 1.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-CCHC PF00098.23 GBG90061.1 - 2.2e-05 24.3 1.4 5.4e-05 23.1 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle Adaptin_binding PF10199.9 GBG90061.1 - 0.00098 19.7 1.3 0.11 13.2 0.3 2.5 2 0 0 2 2 2 2 Alpha and gamma adaptin binding protein p34 zf-CCHC_2 PF13696.6 GBG90061.1 - 0.011 15.6 2.5 0.022 14.6 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Cwf_Cwc_15 PF04889.12 GBG90061.1 - 0.13 12.0 19.4 0.23 11.2 19.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LRR_4 PF12799.7 GBG90063.1 - 9.7e-05 22.7 8.9 0.0008 19.8 1.7 2.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG90063.1 - 0.00022 20.9 0.1 0.00034 20.3 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 GBG90063.1 - 0.0051 17.2 5.0 1.4 9.7 0.3 3.4 3 1 0 3 3 3 2 Leucine Rich Repeat gag-asp_proteas PF13975.6 GBG90064.1 - 5.1e-10 39.8 0.0 1.9e-09 37.9 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90064.1 - 3.2e-07 30.9 0.0 1.1e-06 29.1 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG90064.1 - 0.0024 18.1 0.1 0.012 15.9 0.1 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 GBG90064.1 - 0.025 14.4 0.3 0.061 13.1 0.1 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease rve PF00665.26 GBG90065.1 - 2.9e-14 53.3 0.0 5.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG90065.1 - 3e-13 49.7 0.1 7.3e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG90065.1 - 0.03 14.6 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger HALZ PF02183.18 GBG90065.1 - 0.036 14.3 1.1 0.12 12.7 1.1 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 GBG90065.1 - 0.05 13.7 2.0 0.14 12.3 2.0 1.8 1 0 0 1 1 1 0 Basic region leucine zipper STI1 PF17830.1 GBG90065.1 - 0.085 12.8 0.2 0.27 11.2 0.1 1.9 2 0 0 2 2 2 0 STI1 domain bZIP_1 PF00170.21 GBG90065.1 - 0.18 11.9 1.2 0.63 10.2 1.2 1.9 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 GBG90065.1 - 0.2 11.4 2.8 0.15 11.8 0.4 2.1 2 0 0 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 GBG90065.1 - 0.23 11.7 2.8 1.2 9.4 1.0 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain ZapB PF06005.12 GBG90065.1 - 0.5 10.9 4.8 0.75 10.3 1.5 2.8 3 0 0 3 3 3 0 Cell division protein ZapB GvpL_GvpF PF06386.11 GBG90065.1 - 7.7 6.4 10.8 0.42 10.5 4.0 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Pkinase_Tyr PF07714.17 GBG90066.1 - 2.4e-41 141.7 1.0 7.6e-41 140.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90066.1 - 2.1e-37 129.0 0.0 2.1e-37 129.0 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Es2 PF09751.9 GBG90066.1 - 0.0026 17.6 14.9 0.0039 17.0 14.9 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 LRR_8 PF13855.6 GBG90066.1 - 0.038 13.7 2.3 0.28 11.0 2.3 2.3 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 GBG90066.1 - 0.054 13.9 0.2 0.14 12.6 0.2 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LexA_DNA_bind PF01726.16 GBG90066.1 - 0.059 13.2 0.2 3 7.7 0.0 2.6 2 0 0 2 2 2 0 LexA DNA binding domain LRR_1 PF00560.33 GBG90066.1 - 0.06 13.9 0.5 1.2 10.0 0.2 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat APH PF01636.23 GBG90066.1 - 0.071 13.0 0.1 0.3 11.0 0.1 2.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG90066.1 - 0.23 10.4 0.0 0.23 10.4 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain RT_RNaseH_2 PF17919.1 GBG90067.1 - 2.7e-19 69.1 0.0 4.9e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90067.1 - 4.1e-19 68.8 0.0 1.5e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90067.1 - 2.3e-11 43.9 0.0 6.2e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG90067.1 - 5.4e-05 23.7 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90067.1 - 0.00049 20.7 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG90067.1 - 0.00079 19.7 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG90067.1 - 0.0031 17.0 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG90067.1 - 0.0034 17.1 0.0 0.012 15.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG90067.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF659 PF04937.15 GBG90070.1 - 1.9e-38 131.7 0.0 3.9e-38 130.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG90070.1 - 2.5e-35 122.0 0.0 4.5e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 GBG90070.1 - 3.8e-08 33.0 0.8 9.2e-08 31.8 0.8 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PRIMA1 PF16101.5 GBG90071.1 - 2.1 8.4 6.3 8.1 6.5 1.2 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF659 PF04937.15 GBG90072.1 - 1.4e-21 77.0 0.0 2.3e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90072.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG90073.1 - 1e-26 92.9 0.0 2e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90073.1 - 4.5e-24 84.8 0.0 8.2e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90073.1 - 1.3e-18 66.8 0.4 3.5e-18 65.4 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90073.1 - 5.7e-09 36.2 0.0 1.7e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90073.1 - 0.0061 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 GBG90073.1 - 0.0096 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ArgoL2 PF16488.5 GBG90074.1 - 0.0009 19.5 0.0 58 4.1 0.0 6.3 4 2 3 7 7 7 0 Argonaute linker 2 domain DsrH PF04077.12 GBG90074.1 - 0.0079 16.3 1.5 52 4.1 0.1 5.0 3 2 3 7 7 7 0 DsrH like protein SeleniumBinding PF11524.8 GBG90074.1 - 0.018 15.5 9.1 0.98 9.9 0.2 3.9 3 1 1 4 4 4 0 Selenium binding protein DUF3950 PF13132.6 GBG90074.1 - 0.63 9.8 3.9 14 5.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) Elong-fact-P_C PF09285.11 GBG90074.1 - 0.92 9.3 10.2 24 4.8 1.0 5.0 3 2 3 6 6 6 0 Elongation factor P, C-terminal ICL PF00463.21 GBG90074.1 - 5.4 5.4 6.9 8 4.8 0.2 3.3 1 1 3 4 4 4 0 Isocitrate lyase family RT_RNaseH_2 PF17919.1 GBG90076.1 - 2.6e-21 75.5 0.0 6e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90076.1 - 2.3e-20 72.9 0.0 8.7e-20 71.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90076.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG90077.1 - 9e-05 23.0 0.0 0.00028 21.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90077.1 - 0.00014 22.5 0.0 0.00041 20.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG90077.1 - 0.00034 20.9 0.1 0.00096 19.4 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG90077.1 - 0.04 13.7 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG90077.1 - 0.091 13.1 0.4 0.22 11.8 0.4 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Dimer_Tnp_hAT PF05699.14 GBG90078.1 - 1.5e-10 40.8 0.2 3.4e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Peptidase_C54 PF03416.19 GBG90080.1 - 0.00016 21.2 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Tmemb_14 PF03647.13 GBG90081.1 - 7.5e-23 81.1 15.8 9.2e-23 80.8 15.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Ribosomal_L22e PF01776.17 GBG90083.1 - 6.4e-44 148.8 3.8 1e-43 148.1 3.8 1.2 1 0 0 1 1 1 1 Ribosomal L22e protein family RVP_2 PF08284.11 GBG90084.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG90084.1 - 0.1 12.3 2.1 0.087 12.5 0.3 1.9 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG90084.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG90084.1 - 0.16 12.7 0.1 0.4 11.3 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease TcdA_TcdB PF12919.7 GBG90085.1 - 0.05 12.9 0.1 0.51 9.6 0.0 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain HEV_ORF1 PF02444.16 GBG90086.1 - 0.065 13.8 1.4 0.2 12.2 0.5 2.2 1 1 2 3 3 3 0 Hepatitis E virus ORF-2 (Putative capsid protein) Med13_C PF06333.12 GBG90086.1 - 0.27 10.4 5.1 0.56 9.4 4.5 1.7 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Vac17 PF17321.2 GBG90086.1 - 0.51 9.7 5.1 0.7 9.3 5.1 1.1 1 0 0 1 1 1 0 Vacuole-related protein 17 CDC45 PF02724.14 GBG90087.1 - 0.13 10.5 11.5 0.17 10.2 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG90087.1 - 0.45 9.8 18.9 0.59 9.4 18.9 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG90087.1 - 0.5 9.7 18.1 0.72 9.2 18.1 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG90087.1 - 0.95 8.2 7.0 1.2 7.8 7.0 1.1 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 GBG90087.1 - 1.5 8.2 16.7 2.1 7.6 16.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LAP1C PF05609.12 GBG90087.1 - 3.5 6.6 9.1 4.6 6.2 9.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG90087.1 - 4.6 5.3 19.0 6 4.9 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG90087.1 - 6.1 5.3 20.2 9.3 4.7 20.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.11 GBG90087.1 - 6.7 4.7 8.5 9.7 4.1 8.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen gag-asp_proteas PF13975.6 GBG90088.1 - 1.7e-07 31.7 0.4 4e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90088.1 - 6.2e-06 26.8 0.1 1.5e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG90088.1 - 0.00013 21.7 0.1 0.00025 20.8 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG90088.1 - 0.0062 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG90088.1 - 0.18 11.9 3.7 0.13 12.4 1.9 1.7 2 0 0 2 2 2 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 GBG90089.1 - 0.0002 21.7 4.3 0.00024 21.4 2.6 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG90089.1 - 0.0062 16.6 0.4 0.013 15.6 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG90089.1 - 0.04 14.2 3.2 0.094 13.0 0.9 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like 7TM_GPCR_Srh PF10318.9 GBG90089.1 - 0.47 9.4 1.1 1.3 8.0 0.1 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh DDE_Tnp_4 PF13359.6 GBG90090.1 - 3.4e-28 98.3 0.0 8.3e-28 97.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90090.1 - 1.6e-11 44.2 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein PPDK_N PF01326.19 GBG90091.1 - 7.8e-38 130.6 0.0 3e-35 122.1 0.0 2.4 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 GBG90091.1 - 2.1e-37 128.8 0.9 3e-37 128.3 0.9 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 GBG90091.1 - 3.8e-20 71.4 2.0 3.8e-20 71.4 2.0 2.1 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain RVT_1 PF00078.27 GBG90092.1 - 1.4e-18 67.3 0.1 2.2e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90092.1 - 2.5e-17 62.7 0.2 6.5e-17 61.4 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90092.1 - 3.1e-16 59.5 0.0 5.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90092.1 - 5.4e-09 36.0 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG90092.1 - 0.038 14.2 0.0 0.088 13.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG90094.1 - 9e-23 80.9 0.0 1.6e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG90094.1 - 2.1e-05 25.2 1.1 2.1e-05 25.2 1.1 3.3 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase DALR_1 PF05746.15 GBG90094.1 - 0.1 12.8 0.1 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 DALR anticodon binding domain RT_RNaseH_2 PF17919.1 GBG90096.1 - 1.1e-34 118.4 0.0 1.8e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90096.1 - 4.5e-31 107.3 0.0 8.1e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90096.1 - 3.1e-08 33.4 0.1 4.5e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LCD1 PF09798.9 GBG90097.1 - 1.3 7.5 10.3 1.3 7.4 10.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein RVT_1 PF00078.27 GBG90098.1 - 5.3e-30 104.6 2.8 8.8e-30 103.9 0.1 2.7 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG90098.1 - 1.4e-21 76.7 0.0 7.3e-21 74.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90098.1 - 9.6e-21 73.7 0.0 4.3e-20 71.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90098.1 - 1.4e-08 34.9 0.0 6.8e-08 32.7 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG90098.1 - 0.00039 20.3 0.0 0.0013 18.6 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RVP_2 PF08284.11 GBG90098.1 - 0.0029 17.4 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG90098.1 - 0.017 15.4 0.5 0.23 11.8 0.0 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein Phage_CII PF05269.11 GBG90098.1 - 0.12 12.7 0.4 0.35 11.1 0.4 1.8 1 0 0 1 1 1 0 Bacteriophage CII protein DUF4187 PF13821.6 GBG90098.1 - 1.3 8.9 5.6 0.23 11.3 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf-RVT PF13966.6 GBG90100.1 - 1.5e-05 25.6 4.5 4.1e-05 24.2 4.5 1.9 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Myb_DNA-bind_4 PF13837.6 GBG90101.1 - 1.3e-09 38.3 0.2 3.2e-09 37.0 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG90101.1 - 0.059 13.7 0.2 0.14 12.5 0.2 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 GBG90102.1 - 9.4e-20 70.9 0.0 1.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Kelch_3 PF13415.6 GBG90102.1 - 1.4e-10 41.2 0.4 2.4e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GBG90102.1 - 3.4e-10 39.8 0.3 5.6e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 GBG90102.1 - 6.8e-10 38.8 0.2 0.00011 22.2 0.1 2.9 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG90102.1 - 2.4e-09 37.0 1.7 0.00017 21.5 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 GBG90102.1 - 1.7e-06 27.5 1.6 0.015 14.9 0.1 2.8 2 1 0 2 2 2 2 Kelch motif Plant_tran PF04827.14 GBG90102.1 - 2.1e-05 24.2 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 GBG90103.1 - 9.1e-20 70.9 0.0 1.5e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Kelch_3 PF13415.6 GBG90103.1 - 8.6e-13 48.2 0.3 2.3e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_4 PF13418.6 GBG90103.1 - 4.3e-12 45.8 0.2 0.00011 22.2 0.1 2.7 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GBG90103.1 - 9.2e-11 41.6 0.3 5.5e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 GBG90103.1 - 2.3e-10 40.2 1.4 0.00016 21.5 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 GBG90103.1 - 1.6e-07 30.8 1.5 0.014 14.9 0.1 2.8 2 1 0 2 2 2 2 Kelch motif Plant_tran PF04827.14 GBG90103.1 - 2.1e-05 24.2 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Kelch_2 PF07646.15 GBG90103.1 - 0.035 14.1 0.1 3.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 GBG90104.1 - 1.3e-09 38.1 0.0 3.6e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GBG90104.1 - 5.6e-08 32.2 0.1 1.2e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 GBG90104.1 - 1.4e-06 28.1 0.1 2.8e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 GBG90104.1 - 1.6e-06 28.1 0.0 7.8e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 GBG90104.1 - 1.6e-05 24.8 0.1 9.6e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 GBG90104.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Galactose oxidase, central domain Muskelin_N PF06588.11 GBG90104.1 - 0.002 18.1 0.1 0.0028 17.6 0.1 1.2 1 0 0 1 1 1 1 Muskelin N-terminus RT_RNaseH_2 PF17919.1 GBG90105.1 - 5.7e-34 116.1 0.1 1.3e-33 114.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90105.1 - 1.1e-29 102.8 0.1 3.6e-29 101.1 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90105.1 - 7.2e-29 100.9 0.0 1.4e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90105.1 - 3.5e-13 49.8 0.0 1.9e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG90105.1 - 0.12 12.3 0.0 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain DDE_Tnp_4 PF13359.6 GBG90107.1 - 2.3e-07 30.6 0.0 3.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5310 PF17237.2 GBG90107.1 - 0.21 11.5 0.3 0.39 10.6 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5310) RVT_1 PF00078.27 GBG90109.1 - 3.6e-31 108.4 0.1 7.2e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90109.1 - 2e-29 101.5 0.1 6.4e-29 99.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90109.1 - 1.7e-27 95.8 0.4 4e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Muskelin_N PF06588.11 GBG90109.1 - 1.9e-20 73.6 0.0 3.8e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Muskelin N-terminus Integrase_H2C2 PF17921.1 GBG90109.1 - 1.3e-16 60.5 0.6 2.8e-16 59.3 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90109.1 - 6.9e-16 58.5 0.0 2.3e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90109.1 - 0.0079 16.4 0.1 0.023 14.9 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG90109.1 - 0.22 11.1 0.1 0.44 10.1 0.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DNA_ligase_A_M PF01068.21 GBG90111.1 - 3.6e-16 59.4 0.0 6.6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 GBG90111.1 - 0.00098 19.5 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA ligase Asp_protease_2 PF13650.6 GBG90112.1 - 2e-08 34.8 0.0 3.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90112.1 - 1.1e-07 32.4 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG90112.1 - 2.2e-07 30.7 0.0 3.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG90112.1 - 1.7e-05 24.6 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG90113.1 - 8.3e-11 41.8 0.1 1.4e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_ligase_IV PF11411.8 GBG90113.1 - 1.6e-05 25.0 1.0 3.2e-05 24.0 1.0 1.5 1 0 0 1 1 1 1 DNA ligase IV Chromo PF00385.24 GBG90113.1 - 0.029 14.3 0.1 0.061 13.2 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Hydrolase_4 PF12146.8 GBG90114.1 - 1e-57 195.1 0.0 1.4e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG90114.1 - 2.5e-11 44.6 0.0 3.3e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GBG90114.1 - 3.9e-08 33.2 0.0 5.3e-06 26.3 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GBG90114.1 - 4.3e-06 26.4 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GBG90114.1 - 0.00019 21.3 0.0 0.9 9.3 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 GBG90114.1 - 0.021 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 GBG90114.1 - 0.034 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.14 GBG90115.1 - 3.1e-46 157.6 0.0 4.6e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 GBG90115.1 - 1.8e-05 24.7 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF900 PF05990.12 GBG90115.1 - 0.027 14.0 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 GBG90115.1 - 0.028 14.1 0.5 0.34 10.6 0.5 2.2 1 1 0 1 1 1 0 PGAP1-like protein SAPS PF04499.15 GBG90115.1 - 0.28 9.9 8.5 0.35 9.6 8.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 GBG90115.1 - 1.7 7.0 29.5 2.4 6.5 29.5 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GBG90115.1 - 2.7 6.1 36.4 3.4 5.8 36.4 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 GBG90115.1 - 3.1 8.2 7.2 5.3 7.5 7.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 BUD22 PF09073.10 GBG90115.1 - 3.8 6.8 26.8 4.9 6.4 26.8 1.1 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.13 GBG90115.1 - 4.8 6.1 23.7 7.6 5.4 23.7 1.2 1 0 0 1 1 1 0 Paf1 CDC27 PF09507.10 GBG90115.1 - 8.9 5.6 19.5 12 5.1 19.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3657 PF12394.8 GBG90116.1 - 1.8e-13 50.8 0.2 1.8e-13 50.8 0.2 2.5 3 1 0 3 3 3 1 Protein FAM135 LMBR1 PF04791.16 GBG90117.1 - 0.023 13.6 4.4 0.037 13.0 4.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein APOBEC_C PF05240.14 GBG90117.1 - 0.056 13.4 0.2 0.18 11.8 0.2 1.9 1 0 0 1 1 1 0 APOBEC-like C-terminal domain DUF5069 PF16798.5 GBG90117.1 - 0.07 13.3 7.2 0.077 13.2 0.8 3.2 3 2 1 4 4 4 0 Domain of unknown function (DUF5069) Pex24p PF06398.11 GBG90117.1 - 0.12 11.3 0.5 0.22 10.5 0.5 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DNA_pack_N PF02500.15 GBG90117.1 - 1.3 8.8 4.6 0.79 9.5 0.2 2.1 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus PEP-utilisers_N PF05524.13 GBG90117.1 - 1.5 9.0 14.1 0.096 12.9 6.8 2.3 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal MGC-24 PF05283.11 GBG90118.1 - 2.5 8.6 4.8 8.3 6.9 0.4 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF809 PF05663.11 GBG90118.1 - 7.3 6.7 11.6 6.3 7.0 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF809) CSN5_C PF18323.1 GBG90118.1 - 9.7 7.2 8.6 13 6.8 0.5 2.4 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain RVT_1 PF00078.27 GBG90119.1 - 1.4e-29 103.2 0.1 2.7e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG90119.1 - 9.4e-29 99.8 0.2 1.9e-28 98.8 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90119.1 - 1.2e-25 89.4 0.0 2.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90119.1 - 3.7e-19 68.6 0.0 9.3e-19 67.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90119.1 - 1.1e-13 51.4 0.0 2.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90119.1 - 0.0054 16.9 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF3729 PF12526.8 GBG90119.1 - 2.8 9.5 7.2 7.9 8.1 7.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) RT_RNaseH_2 PF17919.1 GBG90121.1 - 6.5e-34 116.0 0.0 1.2e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90121.1 - 9.9e-30 102.9 0.0 2.2e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90121.1 - 5.7e-18 64.8 0.1 1.1e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90121.1 - 8e-17 61.5 0.1 3.8e-16 59.3 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain DUF1786 PF08735.10 GBG90121.1 - 0.014 14.6 0.1 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) rve_3 PF13683.6 GBG90121.1 - 0.16 11.8 0.0 0.54 10.1 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain RMI1_N PF08585.12 GBG90122.1 - 0.19 11.5 2.6 0.32 10.7 2.6 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein DDRGK PF09756.9 GBG90122.1 - 0.53 9.8 12.9 0.84 9.2 12.9 1.2 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 GBG90122.1 - 0.64 9.8 4.7 1 9.1 4.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 GBG90122.1 - 1.5 9.3 7.2 2.6 8.5 3.0 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Protamine_P2 PF00841.19 GBG90123.1 - 0.0014 19.0 13.1 0.0018 18.7 13.1 1.1 1 0 0 1 1 1 1 Sperm histone P2 CCDC106 PF15794.5 GBG90123.1 - 0.063 13.0 2.1 0.068 12.9 2.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TT_ORF1 PF02956.14 GBG90123.1 - 3.9 6.0 9.1 3.7 6.1 9.1 1.1 1 0 0 1 1 1 0 TT viral orf 1 Protamine_P2 PF00841.19 GBG90124.1 - 0.0058 17.1 13.8 0.0075 16.7 13.8 1.1 1 0 0 1 1 1 1 Sperm histone P2 TT_ORF1 PF02956.14 GBG90124.1 - 9 4.8 10.5 8.9 4.9 10.5 1.1 1 0 0 1 1 1 0 TT viral orf 1 FancD2 PF14631.6 GBG90125.1 - 0.83 7.0 5.2 0.96 6.8 5.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Keratin_2_tail PF16210.5 GBG90125.1 - 4.1 7.7 21.9 5.5 7.2 21.9 1.1 1 0 0 1 1 1 0 Keratin type II cytoskeletal 1 tail Protamine_P2 PF00841.19 GBG90126.1 - 0.0015 18.9 12.2 0.0018 18.7 12.2 1.1 1 0 0 1 1 1 1 Sperm histone P2 TRAP_alpha PF03896.16 GBG90127.1 - 0.059 12.6 9.3 0.073 12.3 9.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 GBG90127.1 - 0.082 11.1 14.7 0.08 11.2 14.7 1.0 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 GBG90127.1 - 0.086 12.7 1.9 0.091 12.6 1.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TFB6 PF17110.5 GBG90127.1 - 0.35 10.6 4.5 0.36 10.5 4.5 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Astro_capsid_p PF12226.8 GBG90127.1 - 0.88 8.7 12.6 0.92 8.6 12.6 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 GBG90127.1 - 1.2 8.4 23.0 1.6 8.0 23.0 1.3 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 GBG90127.1 - 1.3 7.0 7.4 1.4 6.9 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SGT1 PF07093.11 GBG90127.1 - 5.1 5.4 8.8 5.2 5.4 8.8 1.0 1 0 0 1 1 1 0 SGT1 protein FYDLN_acid PF09538.10 GBG90127.1 - 5.6 7.7 21.4 8.4 7.1 21.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RRN3 PF05327.11 GBG90127.1 - 8.5 4.8 12.6 7.9 4.9 12.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 THOC2_N PF16134.5 GBG90127.1 - 9.4 4.7 6.9 11 4.6 6.9 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF659 PF04937.15 GBG90128.1 - 8.7e-18 64.6 0.4 1.7e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90128.1 - 5e-07 29.4 0.1 1.3e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CMS1 PF14617.6 GBG90128.1 - 1.8 7.8 4.0 1.3 8.3 0.1 2.5 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit RT_RNaseH_2 PF17919.1 GBG90129.1 - 1.4e-17 63.6 0.0 3.7e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90129.1 - 4.1e-09 36.7 0.0 4.3e-08 33.4 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Arm PF00514.23 GBG90129.1 - 0.14 12.3 0.0 22 5.3 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF3138 PF11336.8 GBG90129.1 - 0.46 9.0 1.4 0.72 8.4 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ank_5 PF13857.6 GBG90130.1 - 3e-15 56.1 0.4 4.5e-08 33.2 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GBG90130.1 - 4.9e-15 55.7 0.8 2.6e-08 34.2 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG90130.1 - 1.2e-11 43.8 0.1 7.1e-05 22.9 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 GBG90130.1 - 1.2e-11 45.0 0.1 2.6e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GBG90130.1 - 1.4e-11 44.2 0.7 5.4e-06 26.6 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat ETRAMP PF09716.10 GBG90130.1 - 0.21 11.7 8.7 7.6 6.7 2.6 3.3 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) HEAT_2 PF13646.6 GBG90131.1 - 0.00051 20.4 0.1 0.0058 17.0 0.1 1.9 2 0 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 GBG90131.1 - 0.0023 18.0 0.1 0.0026 17.8 0.1 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GBG90131.1 - 0.0028 17.7 0.2 0.79 10.2 0.1 3.0 3 0 0 3 3 3 1 HEAT repeat Adaptin_N PF01602.20 GBG90131.1 - 0.035 12.7 0.0 0.038 12.6 0.0 1.0 1 0 0 1 1 1 0 Adaptin N terminal region GIY-YIG PF01541.24 GBG90133.1 - 1.2e-05 25.4 0.0 3.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG90133.1 - 6.9e-05 22.7 4.0 6.9e-05 22.7 4.0 1.9 2 0 0 2 2 2 1 Zinc knuckle SDA1 PF05285.12 GBG90133.1 - 0.00095 18.7 24.4 0.00095 18.7 24.4 2.9 3 0 0 3 3 3 1 SDA1 AAA_23 PF13476.6 GBG90133.1 - 0.035 14.6 15.9 0.34 11.4 0.6 2.6 2 0 0 2 2 2 0 AAA domain BUD22 PF09073.10 GBG90133.1 - 0.14 11.5 42.7 0.046 13.1 23.5 2.4 2 0 0 2 2 2 0 BUD22 zf-CCHC_5 PF14787.6 GBG90133.1 - 0.22 11.3 3.1 0.5 10.1 3.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Mpp10 PF04006.12 GBG90133.1 - 5.7 5.3 44.2 0.5 8.7 30.8 2.3 2 0 0 2 2 2 0 Mpp10 protein RVT_1 PF00078.27 GBG90134.1 - 6.8e-36 123.9 0.0 1.1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90134.1 - 4.3e-12 45.9 0.0 9.7e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG90134.1 - 4.1e-07 29.8 0.0 8.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90134.1 - 2.8e-06 27.9 0.0 6.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90134.1 - 4e-05 24.1 0.1 0.00016 22.2 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG90134.1 - 0.0037 17.1 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG90134.1 - 0.023 14.5 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease RT_RNaseH PF17917.1 GBG90134.1 - 0.07 13.4 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Glyco_transf_34 PF05637.12 GBG90135.1 - 4.8e-29 101.8 0.4 1.4e-28 100.3 0.4 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_transf_34 PF05637.12 GBG90136.1 - 1.6e-25 90.2 0.4 4.2e-25 88.9 0.4 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF3641 PF12345.8 GBG90138.1 - 1.4e-36 125.5 0.0 2.2e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 GBG90138.1 - 7.6e-06 26.4 0.0 1.2e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF362 PF04015.12 GBG90138.1 - 0.19 11.9 0.0 6.5 6.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF362) RVT_1 PF00078.27 GBG90139.1 - 4.3e-25 88.5 0.1 7.5e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3641 PF12345.8 GBG90140.1 - 2.3e-35 121.6 0.0 3.8e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 GBG90140.1 - 0.00016 22.1 0.0 0.00023 21.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily DUF362 PF04015.12 GBG90140.1 - 0.16 12.2 0.0 8 6.6 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF362) DUF3641 PF12345.8 GBG90141.1 - 1.5e-35 122.2 0.0 3e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 GBG90141.1 - 6.6e-08 33.1 0.0 2.4e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 GBG90141.1 - 0.0013 19.0 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3641 PF12345.8 GBG90142.1 - 1.3e-34 119.1 0.0 2.1e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 GBG90142.1 - 0.04 14.3 0.0 0.062 13.7 0.0 1.2 1 0 0 1 1 1 0 Radical SAM superfamily RVT_1 PF00078.27 GBG90143.1 - 1.3e-27 96.8 0.1 1.9e-27 96.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90143.1 - 1.3e-20 73.3 0.0 3.5e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90143.1 - 1.4e-18 66.7 0.4 8.7e-18 64.2 0.1 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90143.1 - 2.4e-10 40.6 0.0 6.5e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90143.1 - 9.6e-10 38.7 0.0 3.7e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG90143.1 - 0.14 12.5 0.3 0.66 10.3 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG90144.1 - 2.9e-23 82.1 0.0 5.3e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90144.1 - 1.7e-22 79.3 0.0 3.2e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90144.1 - 8e-19 67.5 1.3 1.8e-18 66.4 1.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90144.1 - 1.5e-15 57.5 0.0 3.5e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG90144.1 - 3.5e-14 52.9 0.0 6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG90144.1 - 0.092 12.5 1.7 0.16 11.8 0.3 2.0 2 0 0 2 2 2 0 Aspartyl protease zf-H2C2 PF09337.10 GBG90144.1 - 0.13 12.5 0.2 0.32 11.3 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF4232 PF14016.6 GBG90144.1 - 0.45 10.7 5.6 1.8 8.7 5.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) CDC45 PF02724.14 GBG90144.1 - 4.2 5.6 10.6 6.2 5.0 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 GBG90144.1 - 4.6 6.5 9.8 7.2 5.9 9.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) zf-CCHC PF00098.23 GBG90145.1 - 0.097 12.8 0.4 0.2 11.8 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle BHD_2 PF10404.9 GBG90146.1 - 0.72 10.9 6.2 0.64 11.0 0.3 2.4 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 Tankyrase_bdg_C PF15327.6 GBG90146.1 - 2.2 8.7 8.4 0.25 11.8 1.6 2.0 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain dCMP_cyt_deam_1 PF00383.23 GBG90148.1 - 1.8e-07 31.0 0.4 0.0012 18.7 0.2 3.2 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GBG90148.1 - 3.9e-05 23.4 0.1 0.0089 15.8 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 GBG90148.1 - 0.01 15.9 2.8 0.039 14.0 0.0 2.9 3 0 0 3 3 3 0 Bd3614-like deaminase Histone PF00125.24 GBG90150.1 - 2.4e-27 95.9 0.8 6.6e-27 94.4 0.8 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GBG90150.1 - 0.048 14.0 2.0 0.06 13.7 0.3 2.0 2 0 0 2 2 2 0 CENP-S protein Inositol_P PF00459.25 GBG90151.1 - 2.5e-36 125.6 0.0 2.9e-24 86.0 0.0 2.3 2 0 0 2 2 2 2 Inositol monophosphatase family FBPase PF00316.20 GBG90151.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Adap_comp_sub PF00928.21 GBG90153.1 - 3.5e-66 223.3 0.0 4.2e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GBG90153.1 - 8.4e-10 38.7 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PPR_2 PF13041.6 GBG90154.1 - 9.3e-98 320.3 12.2 2.9e-13 49.8 0.0 13.4 3 2 11 14 14 14 13 PPR repeat family PPR PF01535.20 GBG90154.1 - 3.7e-79 255.6 24.1 2.5e-08 33.6 0.1 14.5 14 1 0 14 14 14 12 PPR repeat PPR_3 PF13812.6 GBG90154.1 - 5.6e-76 250.6 0.0 7e-12 45.3 0.0 8.5 3 2 4 9 9 9 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 GBG90154.1 - 3.7e-69 228.1 0.0 8.7e-08 31.7 0.0 13.5 13 0 0 13 13 13 9 PPR repeat PPR_long PF17177.4 GBG90154.1 - 8.3e-43 146.2 0.0 2.9e-06 26.8 0.0 6.1 1 1 4 6 6 6 6 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GBG90154.1 - 8.7e-12 45.4 12.5 0.084 13.4 0.1 7.6 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 GBG90154.1 - 2.3e-11 43.5 31.0 2.5 9.1 0.6 11.6 6 2 6 12 12 12 4 Tetratricopeptide repeat TPR_16 PF13432.6 GBG90154.1 - 5.1e-10 39.8 22.9 0.0042 17.7 1.0 7.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 GBG90154.1 - 3.4e-09 36.1 14.4 5.3 7.3 0.0 9.8 10 0 0 10 10 10 1 Tetratricopeptide repeat BTAD PF03704.17 GBG90154.1 - 1.2e-06 29.0 20.1 0.63 10.5 0.1 7.7 4 2 2 7 7 7 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 GBG90154.1 - 4.3e-06 26.8 29.4 4.5 8.2 0.0 11.4 12 0 0 12 12 10 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GBG90154.1 - 4.9e-06 26.6 7.1 1.3 8.9 0.1 6.4 3 2 3 6 6 6 1 Virulence factor membrane-bound polymerase, C-terminal ECSIT PF06239.11 GBG90154.1 - 7.2e-06 25.3 0.0 20 4.2 0.0 6.8 3 1 3 7 7 7 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_15 PF13429.6 GBG90154.1 - 1.3e-05 24.5 4.9 0.39 9.9 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GBG90154.1 - 2.6e-05 24.4 24.5 1.6 9.1 0.2 9.4 7 1 3 10 10 10 1 Tetratricopeptide repeat Clathrin PF00637.20 GBG90154.1 - 0.00021 21.2 0.0 16 5.3 0.0 5.5 3 1 3 6 6 6 0 Region in Clathrin and VPS ATP13 PF12921.7 GBG90154.1 - 0.0017 18.2 0.0 8.5 6.3 0.0 4.5 3 2 2 5 5 5 0 Mitochondrial ATPase expression TPR_2 PF07719.17 GBG90154.1 - 0.0022 18.0 21.0 2.6 8.4 0.2 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG90154.1 - 0.0035 17.1 12.6 13 5.8 0.1 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG90154.1 - 0.0041 17.3 0.4 0.75 10.1 0.0 4.0 3 3 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3368 PF11848.8 GBG90154.1 - 0.0072 16.1 5.1 1.1 9.1 0.0 5.8 7 1 1 8 8 7 1 Domain of unknown function (DUF3368) DNA_pol3_gamma3 PF12169.8 GBG90154.1 - 0.037 13.9 0.4 15 5.5 0.0 4.3 4 1 1 5 5 5 0 DNA polymerase III subunits gamma and tau domain III Glyco_trans_4_3 PF12000.8 GBG90154.1 - 0.043 13.5 0.2 4.9 6.8 0.0 4.0 3 2 2 5 5 5 0 Glycosyl transferase family 4 group RPN7 PF10602.9 GBG90154.1 - 0.057 13.1 1.2 8.4 6.1 0.0 4.2 3 3 2 5 5 5 0 26S proteasome subunit RPN7 MRP-S27 PF10037.9 GBG90154.1 - 0.088 11.7 0.0 1.5 7.6 0.0 2.7 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_10 PF13374.6 GBG90154.1 - 0.11 12.4 17.3 12 5.9 0.3 7.7 10 0 0 10 10 7 0 Tetratricopeptide repeat Exog_C PF18026.1 GBG90154.1 - 0.11 12.5 3.2 45 4.2 0.0 4.9 6 0 0 6 6 5 0 Endo/exonuclease (EXOG) C-terminal domain DDE_Tnp_4 PF13359.6 GBG90156.1 - 1.2e-20 73.7 0.0 1.1e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90156.1 - 2.8e-10 40.2 0.0 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG90156.1 - 0.0086 16.4 0.4 0.041 14.2 0.0 2.3 3 0 0 3 3 3 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG90156.1 - 0.013 15.2 0.9 0.22 11.1 0.2 2.7 3 0 0 3 3 3 0 Transposase DDE domain Pkinase_Tyr PF07714.17 GBG90157.1 - 1.7e-18 66.9 0.0 8.9e-13 48.1 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 GBG90157.1 - 5.6e-09 35.7 0.0 5.5e-05 22.7 0.0 3.0 3 1 0 3 3 3 2 Protein kinase domain Linocin_M18 PF04454.12 GBG90157.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Integrase_H2C2 PF17921.1 GBG90158.1 - 2.8e-12 46.5 0.0 7.6e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90158.1 - 1e-05 25.7 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG90158.1 - 0.12 13.0 0.0 0.3 11.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SlyX PF04102.12 GBG90158.1 - 0.36 11.5 3.1 1.5 9.5 3.1 2.1 1 0 0 1 1 1 0 SlyX AAR2 PF05282.11 GBG90159.1 - 0.12 11.7 4.6 0.16 11.3 4.6 1.2 1 0 0 1 1 1 0 AAR2 protein DDHD PF02862.17 GBG90159.1 - 0.16 12.1 0.9 0.18 12.0 0.9 1.2 1 0 0 1 1 1 0 DDHD domain ATP11 PF06644.11 GBG90159.1 - 2.1 8.1 9.5 2.7 7.7 9.5 1.1 1 0 0 1 1 1 0 ATP11 protein Sec62 PF03839.16 GBG90159.1 - 3.1 7.3 7.3 3.9 6.9 7.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DASH_Spc19 PF08287.11 GBG90159.1 - 4.3 7.2 16.4 32 4.4 15.5 2.0 2 0 0 2 2 2 0 Spc19 Retrotrans_gag PF03732.17 GBG90160.1 - 0.00075 19.7 0.3 0.0025 18.1 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein Senescence_reg PF04520.13 GBG90160.1 - 0.024 15.5 2.0 0.17 12.7 2.4 1.9 2 0 0 2 2 2 0 Senescence regulator zf-C2H2_2 PF12756.7 GBG90160.1 - 0.097 13.0 0.1 4.3 7.7 0.0 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-CCHC PF00098.23 GBG90161.1 - 8.2e-08 32.0 3.3 2.5e-07 30.4 3.3 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG90161.1 - 0.019 14.7 2.9 0.052 13.3 2.9 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Prok-RING_1 PF14446.6 GBG90161.1 - 0.038 13.9 0.1 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 RE_ApaLI PF09499.10 GBG90161.1 - 0.046 13.4 0.3 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 ApaLI-like restriction endonuclease MDM1 PF15501.6 GBG90162.1 - 0.006 15.8 15.6 0.006 15.8 15.6 2.8 4 0 0 4 4 4 2 Nuclear protein MDM1 DUF572 PF04502.13 GBG90163.1 - 0.036 13.7 6.5 0.055 13.1 6.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Menin PF05053.13 GBG90165.1 - 4.2 5.6 15.0 6.5 5.0 15.0 1.2 1 0 0 1 1 1 0 Menin Auto_anti-p27 PF06677.12 GBG90166.1 - 0.0074 16.4 1.1 0.015 15.4 1.1 1.5 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RT_RNaseH_2 PF17919.1 GBG90168.1 - 1.1e-33 115.2 0.0 2.5e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90168.1 - 3.6e-29 101.1 0.0 8e-29 100.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90168.1 - 4.5e-13 49.4 0.1 1.3e-12 48.0 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Spidroin_MaSp PF11260.8 GBG90168.1 - 0.1 12.9 1.5 0.3 11.4 1.5 1.7 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 RVT_1 PF00078.27 GBG90169.1 - 1.9e-32 112.6 0.1 3.5e-32 111.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90169.1 - 1.6e-12 47.6 0.0 3.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG90169.1 - 7.3e-11 42.0 0.2 4.2e-10 39.6 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain nsp8 PF08717.10 GBG90169.1 - 0.037 13.9 0.0 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 nsp8 replicase eIF-1a PF01176.19 GBG90169.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Chromo PF00385.24 GBG90169.1 - 0.07 13.1 0.0 0.24 11.3 0.0 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF4392 PF14336.6 GBG90170.1 - 0.18 11.2 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) RVP_2 PF08284.11 GBG90170.1 - 0.21 11.4 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Glyco_transf_5 PF08323.11 GBG90171.1 - 4.7e-70 236.1 0.0 6.6e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG90171.1 - 1.1e-17 64.1 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG90171.1 - 6.1e-13 49.4 0.0 1.1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG90171.1 - 0.016 15.3 0.0 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Pkinase_Tyr PF07714.17 GBG90172.1 - 3.3e-30 105.2 0.0 7.5e-30 104.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90172.1 - 6.8e-28 97.8 0.0 1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG90172.1 - 0.017 13.9 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Myb_DNA-bind_4 PF13837.6 GBG90174.1 - 1.6e-08 34.8 1.9 1.6e-07 31.6 2.2 2.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain RVP_2 PF08284.11 GBG90176.1 - 0.00012 21.9 0.0 0.00035 20.4 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90176.1 - 0.001 19.7 0.0 0.0024 18.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90176.1 - 0.0088 16.6 0.3 0.035 14.7 0.0 2.2 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG90176.1 - 0.011 15.6 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Putative peptidase (DUF1758) VTC PF09359.10 GBG90176.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 VTC domain Peptidase_C48 PF02902.19 GBG90177.1 - 8.8e-17 61.7 1.5 1.4e-16 61.0 1.5 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TEX33 PF15400.6 GBG90177.1 - 0.035 14.6 0.1 0.11 12.9 0.1 1.9 1 1 0 1 1 1 0 Testis-expressed sequence 33 protein family zf-CCHC PF00098.23 GBG90178.1 - 5.7e-06 26.2 3.7 1.1e-05 25.3 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG90178.1 - 0.0025 17.7 0.4 0.02 14.9 0.2 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG90178.1 - 0.095 12.5 1.7 0.21 11.4 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle ALMT PF11744.8 GBG90182.1 - 0.21 10.4 16.2 0.31 9.8 16.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 GBG90182.1 - 1.3 7.7 23.4 1.7 7.3 23.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sacchrp_dh_C PF16653.5 GBG90183.1 - 0.013 15.6 0.1 0.014 15.5 0.1 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase C-terminal domain rve PF00665.26 GBG90184.1 - 1.7e-11 44.4 0.0 3.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG90184.1 - 4.5e-05 23.3 0.0 9.1e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG90184.1 - 0.00065 19.9 0.3 0.0015 18.7 0.3 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG90184.1 - 0.0053 16.5 0.6 0.012 15.3 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Lipin_mid PF16876.5 GBG90184.1 - 0.07 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain gag-asp_proteas PF13975.6 GBG90185.1 - 4.9e-09 36.6 0.0 9.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90185.1 - 4.1e-06 27.3 0.0 7.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG90185.1 - 3.4e-05 23.6 0.7 5.6e-05 22.9 0.7 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG90185.1 - 0.00084 19.6 0.0 0.0045 17.3 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease PTPRCAP PF15713.5 GBG90185.1 - 0.044 14.1 7.0 0.083 13.2 7.0 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 GBG90185.1 - 0.29 10.8 4.2 0.49 10.0 4.2 1.3 1 0 0 1 1 1 0 FAM176 family Oxysterol_BP PF01237.18 GBG90185.1 - 1.8 7.3 5.2 2.7 6.7 5.2 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein RPN2_C PF18004.1 GBG90185.1 - 3.3 7.6 8.8 5.1 7.0 8.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DAP10 PF07213.11 GBG90186.1 - 0.00027 20.8 5.9 0.00034 20.5 5.9 1.3 1 0 0 1 1 1 1 DAP10 membrane protein TPPK_C PF12555.8 GBG90186.1 - 0.0056 16.7 10.0 0.012 15.6 10.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal DUF659 PF04937.15 GBG90188.1 - 0.028 14.3 0.1 0.7 9.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF 659) SAP130_C PF16014.5 GBG90188.1 - 0.21 10.6 4.2 0.35 9.9 4.2 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Desulfoferrod_N PF06397.12 GBG90189.1 - 0.11 12.2 1.4 0.29 10.8 1.4 1.8 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain MMU163 PF17119.5 GBG90189.1 - 1.2 8.2 3.3 0.28 10.3 0.1 1.5 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis RVT_1 PF00078.27 GBG90190.1 - 1.3e-28 100.0 0.0 2.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90190.1 - 2.5e-20 72.4 0.0 7.1e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90190.1 - 1.9e-10 41.0 0.0 4.9e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAM76 PF16046.5 GBG90190.1 - 0.1 11.9 8.0 0.2 11.0 8.0 1.4 1 0 0 1 1 1 0 FAM76 protein eIF3_subunit PF08597.10 GBG90190.1 - 1.1 9.2 12.1 1.8 8.4 12.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Sigma70_ner PF04546.13 GBG90190.1 - 1.3 8.8 11.2 2.8 7.8 11.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-RING_4 PF14570.6 GBG90191.1 - 1.3e-18 66.5 9.9 2.6e-18 65.5 9.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 GBG90191.1 - 0.0005 19.9 7.2 0.001 18.8 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RNA_pol_3_Rpc31 PF11705.8 GBG90191.1 - 0.0012 19.1 13.8 0.0012 19.1 13.8 4.2 4 0 0 4 4 4 1 DNA-directed RNA polymerase III subunit Rpc31 zf-RING_2 PF13639.6 GBG90191.1 - 0.019 15.3 10.7 0.044 14.1 10.7 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 GBG90191.1 - 1.3 8.9 11.1 2.5 8.0 11.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GBG90191.1 - 1.6 8.6 9.3 35 4.4 0.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 NOA36 PF06524.12 GBG90191.1 - 2 7.6 17.8 8.8 5.6 17.8 2.1 1 0 0 1 1 1 0 NOA36 protein RT_RNaseH PF17917.1 GBG90192.1 - 1.1e-20 73.9 0.0 5.2e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90192.1 - 8.1e-20 70.7 0.0 8e-19 67.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90192.1 - 1.8e-18 66.4 0.4 5e-18 65.0 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90192.1 - 1.9e-16 60.4 0.0 5.7e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG90192.1 - 1.4e-08 35.2 0.0 3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90192.1 - 1.6e-08 35.0 0.0 3.8e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG90192.1 - 0.0002 21.0 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG90192.1 - 0.00028 20.7 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG90192.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG90192.1 - 0.14 12.4 0.3 0.37 11.1 0.3 1.7 1 0 0 1 1 1 0 H2C2 zinc finger PLAC8 PF04749.17 GBG90193.1 - 6.9e-17 62.3 15.6 1.5e-16 61.1 15.6 1.6 1 1 0 1 1 1 1 PLAC8 family ANAPC3 PF12895.7 GBG90194.1 - 6.5e-17 61.5 1.0 6.5e-17 61.5 1.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC8 PF04049.13 GBG90194.1 - 0.00042 20.4 0.1 0.0013 18.8 0.1 1.7 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.17 GBG90194.1 - 0.0044 17.0 13.5 0.037 14.1 1.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG90194.1 - 0.036 14.7 10.3 0.21 12.3 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 GBG90194.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Putative TPR-like repeat TPR_8 PF13181.6 GBG90194.1 - 0.051 13.8 0.4 0.051 13.8 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GBG90194.1 - 0.052 14.1 4.9 0.073 13.6 1.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG90194.1 - 0.2 12.3 4.2 35 5.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GBG90194.1 - 0.89 10.5 6.5 1.6 9.8 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG90194.1 - 1 9.5 5.0 0.68 10.1 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat rve PF00665.26 GBG90195.1 - 1.8e-15 57.2 0.0 3.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG90195.1 - 8.4e-15 54.6 0.1 8.1e-14 51.5 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG90195.1 - 1.9e-08 34.2 0.0 4.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90195.1 - 3.6e-06 27.5 0.0 1.1e-05 26.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90195.1 - 1.3e-05 25.7 0.0 9.3e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG90195.1 - 6.8e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG90195.1 - 0.0011 19.2 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger CCDC85 PF10226.9 GBG90195.1 - 0.13 11.9 0.6 0.29 10.8 0.6 1.5 1 0 0 1 1 1 0 CCDC85 family bZIP_2 PF07716.15 GBG90195.1 - 0.18 11.9 3.1 0.67 10.1 3.1 2.0 1 0 0 1 1 1 0 Basic region leucine zipper TPR_2 PF07719.17 GBG90196.1 - 9.1e-19 66.0 13.0 1.2e-05 25.0 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 GBG90196.1 - 5.4e-14 51.1 5.0 0.0023 18.0 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG90196.1 - 2.6e-11 42.8 12.1 0.00036 20.2 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG90196.1 - 7.5e-09 35.8 10.3 0.039 14.2 0.2 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GBG90196.1 - 1.8e-07 31.4 8.7 0.57 11.1 0.0 5.8 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG90196.1 - 3e-06 27.8 11.3 0.0026 18.4 0.2 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG90196.1 - 8.4e-06 26.2 2.3 0.057 13.9 0.5 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat EF-hand_1 PF00036.32 GBG90196.1 - 0.00017 20.9 0.0 0.001 18.4 0.0 2.2 2 0 0 2 2 2 1 EF hand ANAPC3 PF12895.7 GBG90196.1 - 0.00046 20.4 13.4 0.0051 17.0 0.6 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GBG90196.1 - 0.00056 20.1 5.8 0.46 11.0 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat EF-hand_7 PF13499.6 GBG90196.1 - 0.00067 20.1 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG90196.1 - 0.00085 19.1 0.0 0.0031 17.3 0.0 1.9 2 0 0 2 2 1 1 EF-hand domain TPR_11 PF13414.6 GBG90196.1 - 0.001 18.7 8.0 1.5 8.6 0.6 4.3 3 2 2 5 5 5 2 TPR repeat EF-hand_5 PF13202.6 GBG90196.1 - 0.0064 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 EF hand TPR_10 PF13374.6 GBG90196.1 - 0.0073 16.1 11.0 0.12 12.2 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat SPO22 PF08631.10 GBG90196.1 - 0.024 14.2 0.0 0.062 12.8 0.0 1.7 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like EF-hand_8 PF13833.6 GBG90196.1 - 0.034 14.0 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair Fis1_TPR_C PF14853.6 GBG90196.1 - 0.31 11.2 4.1 19 5.4 0.1 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 GBG90196.1 - 0.52 11.1 6.2 2.8 8.8 0.1 4.5 5 0 0 5 5 5 0 Sel1 repeat TPR_7 PF13176.6 GBG90196.1 - 2.2 8.5 0.0 2.2 8.5 0.0 4.2 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GBG90196.1 - 4.2 8.2 9.0 5.1 8.0 0.2 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-CCHC PF00098.23 GBG90197.1 - 0.0012 18.8 3.6 0.0012 18.8 3.6 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG90197.1 - 0.028 14.1 1.2 0.069 12.9 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF572 PF04502.13 GBG90197.1 - 0.087 12.4 23.5 0.11 12.0 23.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_C58 PF03543.14 GBG90197.1 - 1.1 9.0 6.8 0.24 11.1 0.5 2.1 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen zf-CCHC_2 PF13696.6 GBG90197.1 - 3.9 7.4 11.4 0.4 10.5 3.9 2.6 3 0 0 3 3 3 0 Zinc knuckle Glyco_transf_29 PF00777.18 GBG90198.1 - 1.9e-26 93.1 0.0 3.8e-25 88.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Collagen PF01391.18 GBG90198.1 - 0.00049 19.8 24.6 0.001 18.8 24.6 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PGM_PMM_I PF02878.16 GBG90199.1 - 7.1e-31 106.8 0.0 1.7e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GBG90199.1 - 7e-28 97.1 0.0 1.6e-27 96.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GBG90199.1 - 2e-11 44.4 0.0 7.1e-11 42.6 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 GBG90199.1 - 7.5e-07 29.2 0.0 3.6e-06 27.1 0.0 2.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Retrotrans_gag PF03732.17 GBG90199.1 - 0.0025 18.1 1.4 0.0057 16.9 0.2 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG90199.1 - 0.0025 17.2 11.9 0.0063 15.9 11.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CENP-K PF11802.8 GBG90199.1 - 0.03 13.9 3.0 0.052 13.1 3.0 1.3 1 0 0 1 1 1 0 Centromere-associated protein K DUF4187 PF13821.6 GBG90199.1 - 0.031 14.1 0.7 0.081 12.7 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Lipin_mid PF16876.5 GBG90199.1 - 0.16 12.1 0.7 0.91 9.7 0.0 2.6 3 0 0 3 3 3 0 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF3801 PF12687.7 GBG90199.1 - 1.5 8.8 8.4 14 5.7 7.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Mt_ATP-synt_B PF05405.14 GBG90199.1 - 2 8.0 9.0 2.6 7.7 8.0 1.7 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4140 PF13600.6 GBG90199.1 - 9.7 6.7 8.4 4.8 7.7 1.1 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pcc1 PF09341.10 GBG90200.1 - 5.6e-14 52.0 0.2 7.1e-14 51.7 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DP PF08781.10 GBG90200.1 - 0.16 11.9 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 Transcription factor DP RVT_1 PF00078.27 GBG90201.1 - 2.2e-35 122.2 0.0 2.8e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG90202.1 - 0.84 7.9 14.4 1.1 7.4 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG90202.1 - 1.6 6.9 18.5 2.1 6.5 18.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG90202.1 - 3.3 7.1 18.7 4.4 6.6 18.7 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG90202.1 - 4.3 6.6 17.4 6 6.1 17.4 1.1 1 0 0 1 1 1 0 BUD22 JmjC PF02373.22 GBG90203.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase Ribosomal_S5 PF00333.20 GBG90204.1 - 1.9e-25 88.6 6.1 7.4e-25 86.7 6.1 2.1 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 GBG90204.1 - 7.9e-24 82.9 1.3 9.5e-24 82.7 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain DUF3568 PF12092.8 GBG90204.1 - 0.053 13.6 2.6 0.15 12.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3568) DUF659 PF04937.15 GBG90205.1 - 4.2e-05 23.4 0.0 6.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) OsmC PF02566.19 GBG90205.1 - 0.037 14.5 0.0 0.089 13.3 0.0 1.6 1 0 0 1 1 1 0 OsmC-like protein DUF659 PF04937.15 GBG90206.1 - 4.6e-13 49.3 0.0 6.7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG90206.1 - 0.019 15.2 0.0 0.88 9.8 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain DUF2946 PF11162.8 GBG90207.1 - 0.4 11.3 3.0 1.5 9.5 3.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) SpoIIIAH PF12685.7 GBG90207.1 - 0.55 10.0 12.6 0.11 12.3 5.4 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Sigma70_ner PF04546.13 GBG90207.1 - 0.61 9.9 0.0 0.61 9.9 0.0 5.4 3 3 0 3 3 3 0 Sigma-70, non-essential region BUD22 PF09073.10 GBG90207.1 - 2.4 7.4 58.2 0.12 11.7 35.0 2.3 2 0 0 2 2 2 0 BUD22 HA2 PF04408.23 GBG90208.1 - 6.3e-17 61.8 0.0 6.3e-17 61.8 0.0 3.1 2 1 0 2 2 1 1 Helicase associated domain (HA2) R3H PF01424.22 GBG90208.1 - 1.4e-11 44.2 0.1 4.9e-11 42.4 0.1 2.0 1 0 0 1 1 1 1 R3H domain Ank_5 PF13857.6 GBG90208.1 - 2.2e-08 34.2 0.3 5.5e-08 32.9 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Helicase_C PF00271.31 GBG90208.1 - 2e-07 31.3 0.0 4.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GBG90208.1 - 7.5e-07 29.4 0.0 1.9e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Ank_2 PF12796.7 GBG90208.1 - 8.6e-06 26.3 0.1 2.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) T2SSE PF00437.20 GBG90208.1 - 0.0007 18.7 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein YL1 PF05764.13 GBG90208.1 - 0.0021 18.3 14.1 0.0045 17.1 14.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein AAA_11 PF13086.6 GBG90208.1 - 0.0042 16.9 3.6 2.9 7.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain CDC45 PF02724.14 GBG90208.1 - 0.0059 15.0 10.5 0.0098 14.2 10.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Ank_4 PF13637.6 GBG90208.1 - 0.0093 16.5 0.0 0.023 15.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG90208.1 - 0.012 16.0 0.0 1.4 9.7 0.0 3.4 3 0 0 3 3 2 0 Ankyrin repeat ATPase PF06745.13 GBG90208.1 - 0.013 14.8 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 KaiC Mpp10 PF04006.12 GBG90208.1 - 0.017 13.6 15.8 0.028 12.9 15.8 1.2 1 0 0 1 1 1 0 Mpp10 protein Sigma70_ner PF04546.13 GBG90208.1 - 0.037 13.9 12.9 0.12 12.2 12.9 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region DEAD PF00270.29 GBG90208.1 - 0.046 13.5 0.1 0.29 10.9 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 GBG90208.1 - 0.052 13.1 0.1 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 GBG90208.1 - 0.076 13.1 0.1 0.8 9.8 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 GBG90208.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Ank PF00023.30 GBG90208.1 - 0.088 13.3 0.3 0.37 11.3 0.3 2.2 1 0 0 1 1 1 0 Ankyrin repeat PRP1_N PF06424.12 GBG90208.1 - 0.094 13.1 12.2 0.24 11.8 12.2 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal PhoH PF02562.16 GBG90208.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Neur_chan_memb PF02932.16 GBG90208.1 - 0.15 12.1 0.2 0.29 11.2 0.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Csc2 PF18320.1 GBG90208.1 - 0.16 10.9 1.0 0.29 10.0 1.0 1.3 1 0 0 1 1 1 0 Csc2 Crispr ABC_tran PF00005.27 GBG90208.1 - 0.17 12.4 0.3 0.48 10.9 0.0 1.9 2 0 0 2 2 1 0 ABC transporter Myosin_head PF00063.21 GBG90208.1 - 0.18 9.9 0.0 0.28 9.3 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) SDA1 PF05285.12 GBG90208.1 - 0.26 10.7 19.6 0.52 9.7 19.6 1.4 1 0 0 1 1 1 0 SDA1 AAA_19 PF13245.6 GBG90208.1 - 0.29 11.5 1.6 11 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain Nop53 PF07767.11 GBG90208.1 - 0.44 9.9 23.0 0.87 8.9 23.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2457 PF10446.9 GBG90208.1 - 0.56 9.3 22.0 0.97 8.5 22.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 GBG90208.1 - 0.57 8.3 23.3 0.84 7.8 23.3 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 GBG90208.1 - 0.59 10.0 9.7 1.3 8.9 9.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region TFB6 PF17110.5 GBG90208.1 - 0.77 9.5 6.7 1.9 8.2 6.7 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH AAA_23 PF13476.6 GBG90208.1 - 1.1 9.8 0.0 1.1 9.8 0.0 2.6 2 0 0 2 2 1 0 AAA domain DUF4820 PF16091.5 GBG90208.1 - 1.4 8.2 6.5 3.9 6.8 6.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 GBG90208.1 - 2.2 8.0 10.1 5.6 6.7 10.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Merozoite_SPAM PF07133.11 GBG90208.1 - 3.2 7.7 34.8 6.9 6.6 34.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HSP90 PF00183.18 GBG90208.1 - 4.1 6.2 14.9 7.1 5.4 14.9 1.3 1 0 0 1 1 1 0 Hsp90 protein HA2 PF04408.23 GBG90209.1 - 8.6e-16 58.2 0.0 8.6e-16 58.2 0.0 3.1 2 1 0 2 2 1 1 Helicase associated domain (HA2) R3H PF01424.22 GBG90209.1 - 1.4e-11 44.2 0.1 4.8e-11 42.5 0.1 2.0 1 0 0 1 1 1 1 R3H domain Ank_5 PF13857.6 GBG90209.1 - 2.2e-08 34.2 0.3 5.4e-08 33.0 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Helicase_C PF00271.31 GBG90209.1 - 2e-07 31.4 0.0 4.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GBG90209.1 - 7.3e-07 29.5 0.0 1.9e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Ank_2 PF12796.7 GBG90209.1 - 8.4e-06 26.3 0.1 2.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) T2SSE PF00437.20 GBG90209.1 - 0.00069 18.8 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein YL1 PF05764.13 GBG90209.1 - 0.002 18.3 14.1 0.0044 17.2 14.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein AAA_11 PF13086.6 GBG90209.1 - 0.0039 17.0 3.5 2.7 7.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain CDC45 PF02724.14 GBG90209.1 - 0.0058 15.0 10.5 0.0097 14.3 10.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Ank_4 PF13637.6 GBG90209.1 - 0.009 16.6 0.0 0.022 15.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG90209.1 - 0.012 16.1 0.0 1.4 9.7 0.0 3.4 3 0 0 3 3 2 0 Ankyrin repeat ATPase PF06745.13 GBG90209.1 - 0.013 14.9 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 KaiC Mpp10 PF04006.12 GBG90209.1 - 0.017 13.6 15.8 0.027 12.9 15.8 1.2 1 0 0 1 1 1 0 Mpp10 protein Sigma70_ner PF04546.13 GBG90209.1 - 0.036 13.9 12.9 0.12 12.2 12.9 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region DEAD PF00270.29 GBG90209.1 - 0.045 13.5 0.1 0.29 10.9 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 GBG90209.1 - 0.05 13.2 0.1 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 GBG90209.1 - 0.073 13.2 0.1 0.78 9.8 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 GBG90209.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Ank PF00023.30 GBG90209.1 - 0.085 13.3 0.3 0.36 11.4 0.3 2.2 1 0 0 1 1 1 0 Ankyrin repeat PRP1_N PF06424.12 GBG90209.1 - 0.092 13.1 12.2 0.24 11.8 12.2 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal PhoH PF02562.16 GBG90209.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Neur_chan_memb PF02932.16 GBG90209.1 - 0.15 12.1 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Csc2 PF18320.1 GBG90209.1 - 0.16 10.9 1.0 0.28 10.1 1.0 1.3 1 0 0 1 1 1 0 Csc2 Crispr ABC_tran PF00005.27 GBG90209.1 - 0.17 12.4 0.3 0.47 11.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter Myosin_head PF00063.21 GBG90209.1 - 0.18 10.0 0.0 0.28 9.4 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) SDA1 PF05285.12 GBG90209.1 - 0.25 10.7 19.6 0.51 9.7 19.6 1.4 1 0 0 1 1 1 0 SDA1 AAA_19 PF13245.6 GBG90209.1 - 0.27 11.5 1.6 11 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain Nop53 PF07767.11 GBG90209.1 - 0.43 9.9 23.0 0.85 8.9 23.0 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2457 PF10446.9 GBG90209.1 - 0.55 9.3 22.0 0.95 8.5 22.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 GBG90209.1 - 0.55 8.4 23.3 0.83 7.8 23.3 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 GBG90209.1 - 0.59 10.0 9.7 1.2 8.9 9.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region TFB6 PF17110.5 GBG90209.1 - 0.75 9.5 6.7 1.8 8.3 6.7 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH AAA_23 PF13476.6 GBG90209.1 - 1 9.8 0.0 1 9.8 0.0 2.5 2 0 0 2 2 1 0 AAA domain DUF4820 PF16091.5 GBG90209.1 - 1.4 8.3 6.5 3.8 6.8 6.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 GBG90209.1 - 2.2 8.0 10.1 5.5 6.7 10.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Merozoite_SPAM PF07133.11 GBG90209.1 - 3.2 7.7 34.8 6.8 6.7 34.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HSP90 PF00183.18 GBG90209.1 - 4 6.2 14.9 6.9 5.4 14.9 1.3 1 0 0 1 1 1 0 Hsp90 protein RT_RNaseH_2 PF17919.1 GBG90211.1 - 5.3e-28 97.0 0.0 3.4e-27 94.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90211.1 - 8.5e-28 96.7 0.3 7e-27 93.8 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90211.1 - 4.9e-18 65.0 0.6 1.2e-17 63.8 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90211.1 - 2.5e-17 63.2 0.0 8.1e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Acetyltransf_1 PF00583.25 GBG90211.1 - 3.9e-14 52.9 0.1 1e-13 51.5 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GBG90211.1 - 3.2e-07 30.3 0.0 1.4e-06 28.3 0.0 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GBG90211.1 - 1.4e-06 28.7 0.5 7.9e-06 26.2 0.1 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain RVT_1 PF00078.27 GBG90211.1 - 0.00049 19.7 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4392 PF14336.6 GBG90211.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) FR47 PF08445.10 GBG90211.1 - 0.06 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Phage_lysozyme PF00959.19 GBG90211.1 - 0.081 13.4 0.0 4.5 7.8 0.0 3.1 2 0 0 2 2 2 0 Phage lysozyme DUF4219 PF13961.6 GBG90211.1 - 0.17 11.6 0.5 12 5.7 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) ADP_ribosyl_GH PF03747.14 GBG90211.1 - 2.6 7.7 6.9 20 4.8 0.0 4.7 5 0 0 5 5 4 0 ADP-ribosylglycohydrolase Rho_GDI PF02115.17 GBG90212.1 - 1.1e-58 198.2 0.0 1.4e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ank_2 PF12796.7 GBG90213.1 - 9.3e-31 106.3 1.0 1.1e-11 45.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ion_trans PF00520.31 GBG90213.1 - 1.9e-20 73.1 10.1 2.8e-20 72.6 10.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 GBG90213.1 - 3.1e-20 72.3 0.4 2e-07 31.4 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG90213.1 - 2.4e-18 64.3 0.2 0.00024 21.3 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GBG90213.1 - 4.9e-18 65.0 1.0 1.7e-10 40.9 0.2 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) cNMP_binding PF00027.29 GBG90213.1 - 4e-16 58.9 0.0 1.2e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ank PF00023.30 GBG90213.1 - 3.5e-15 55.7 1.3 1.4e-05 25.3 0.0 5.5 4 1 0 4 4 4 2 Ankyrin repeat Ion_trans_2 PF07885.16 GBG90213.1 - 2.9e-10 40.0 0.2 6.5e-10 38.8 0.2 1.7 1 0 0 1 1 1 1 Ion channel VWA_3_C PF18571.1 GBG90213.1 - 0.056 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain WD40_alt PF14077.6 GBG90214.1 - 0.0028 17.5 0.7 1.3 8.9 0.1 2.4 2 0 0 2 2 2 2 Alternative WD40 repeat motif Chorismate_synt PF01264.21 GBG90214.1 - 0.021 13.6 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Chorismate synthase PRKG1_interact PF15898.5 GBG90214.1 - 0.028 15.3 4.0 0.043 14.7 4.0 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain GreA_GreB_N PF03449.15 GBG90214.1 - 0.058 13.5 1.6 0.13 12.4 1.6 1.6 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal TMF_TATA_bd PF12325.8 GBG90214.1 - 0.061 13.5 1.5 0.12 12.6 1.5 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 GBG90214.1 - 0.25 11.8 4.0 2 8.9 1.9 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Vta1 PF04652.16 GBG90215.1 - 2.9e-26 92.2 0.5 4e-26 91.7 0.5 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 GBG90215.1 - 5.8e-14 51.5 0.1 1.4e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 Vta1 C-terminal domain RVT_1 PF00078.27 GBG90216.1 - 8.9e-30 103.9 0.1 1.7e-29 102.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90216.1 - 1.6e-25 89.0 0.0 4.9e-25 87.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90216.1 - 1.6e-22 79.7 0.2 1.3e-20 73.6 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase AIP3 PF03915.13 GBG90216.1 - 0.002 17.3 6.1 0.0038 16.4 6.1 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 RVP_2 PF08284.11 GBG90216.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Endonuc-FokI_C PF09254.11 GBG90216.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal USP8_interact PF08941.10 GBG90216.1 - 0.41 10.4 2.2 6.5 6.5 0.9 2.9 3 0 0 3 3 3 0 USP8 interacting TMPIT PF07851.13 GBG90216.1 - 0.54 9.4 4.2 0.91 8.7 0.9 2.3 2 0 0 2 2 2 0 TMPIT-like protein Retrotrans_gag PF03732.17 GBG90216.1 - 0.63 10.3 6.3 14 6.0 0.0 4.7 4 0 0 4 4 4 0 Retrotransposon gag protein PLC-beta_C PF08703.10 GBG90216.1 - 0.9 9.5 15.7 2.1 8.3 15.7 1.5 1 0 0 1 1 1 0 PLC-beta C terminal Ribosomal_60s PF00428.19 GBG90216.1 - 1.5 9.5 5.5 4.4 8.0 5.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAM76 PF16046.5 GBG90216.1 - 6 6.1 8.6 12 5.2 8.6 1.4 1 0 0 1 1 1 0 FAM76 protein Chlorophyllase PF07224.11 GBG90217.1 - 1.1e-97 326.8 0.0 1.4e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 GBG90217.1 - 2.9e-90 301.6 0.0 3.6e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 GBG90217.1 - 1.5e-06 27.0 1.2 3.9e-06 25.6 0.3 1.8 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.18 GBG90217.1 - 0.00058 19.5 0.0 0.00086 18.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 GBG90217.1 - 0.033 14.0 0.3 3.6 7.3 0.1 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG90217.1 - 0.19 10.9 0.8 2.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RT_RNaseH_2 PF17919.1 GBG90218.1 - 1.2e-31 108.7 0.2 2.1e-31 107.9 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90218.1 - 1.1e-27 96.3 0.1 2.4e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90218.1 - 5.7e-16 58.4 0.2 1.4e-15 57.1 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90218.1 - 8.9e-16 58.2 0.1 7e-15 55.3 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.27 GBG90218.1 - 1.8e-12 47.3 0.3 3.5e-12 46.3 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CBS PF00571.28 GBG90219.1 - 1.6e-23 82.9 3.1 6.9e-12 45.6 0.6 2.4 3 0 0 3 3 3 2 CBS domain RT_RNaseH_2 PF17919.1 GBG90220.1 - 8e-20 70.7 0.1 3.8e-19 68.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90220.1 - 3.9e-16 58.9 0.6 1e-15 57.6 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90220.1 - 2.7e-09 37.2 0.0 1e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90220.1 - 6.3e-08 32.8 0.7 1.3e-06 28.6 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG90220.1 - 1.7e-07 31.1 0.0 3.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG90220.1 - 3.8e-06 27.4 0.0 1.8e-05 25.2 0.0 2.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90220.1 - 0.00016 22.2 0.0 0.00075 20.1 0.0 2.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG90220.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG90220.1 - 0.028 14.6 0.2 0.068 13.4 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG90220.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG90220.1 - 7.3 6.9 11.7 0.22 11.8 2.5 3.1 3 1 0 3 3 3 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG90222.1 - 0.00029 21.3 0.0 0.00075 20.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90222.1 - 0.0038 17.8 0.0 0.009 16.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG90222.1 - 0.0065 16.3 0.2 0.017 14.9 0.1 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG90222.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG90222.1 - 0.032 14.5 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein DHHC PF01529.20 GBG90223.1 - 1.1e-31 109.7 3.7 1.1e-31 109.7 3.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.7 GBG90223.1 - 8.4 6.5 13.0 1.7 8.7 7.7 2.2 2 0 0 2 2 2 0 Double zinc ribbon Na_trans_assoc PF06512.13 GBG90224.1 - 0.54 10.5 15.7 0.67 10.2 15.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG90224.1 - 8.8 4.4 35.1 10 4.2 35.1 1.0 1 0 0 1 1 1 0 Nop14-like family PDZ_3 PF17815.1 GBG90226.1 - 5e-48 162.6 0.1 8.2e-48 162.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 GBG90226.1 - 1.6e-20 74.5 1.3 4.5e-20 73.1 1.3 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GBG90226.1 - 2.9e-15 56.7 0.1 5e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 GBG90226.1 - 3.5e-05 24.0 0.0 0.00031 21.0 0.0 2.5 2 0 0 2 2 2 1 PDZ domain TFIIA PF03153.13 GBG90226.1 - 0.0042 17.1 19.1 0.0074 16.3 19.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Peptidase_S46 PF10459.9 GBG90226.1 - 0.0052 15.5 0.1 0.0052 15.5 0.1 2.2 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S39 PF02122.15 GBG90226.1 - 0.15 11.6 1.4 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Peptidase S39 DUF3153 PF11353.8 GBG90226.1 - 1.2 8.6 3.1 2.3 7.8 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) DUF2052 PF09747.9 GBG90226.1 - 3.8 7.6 33.6 2.9 8.0 16.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CPSF100_C PF13299.6 GBG90226.1 - 5.8 7.1 16.5 1.7 8.8 4.9 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal ADK PF00406.22 GBG90227.1 - 1.2e-47 161.8 0.0 3.7e-47 160.2 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 GBG90227.1 - 2.5e-34 118.6 0.0 5.4e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CaMKII_AD PF08332.10 GBG90227.1 - 2.9e-24 85.6 0.0 4.8e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain AAA_33 PF13671.6 GBG90227.1 - 2.2e-06 27.9 0.0 4.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GBG90227.1 - 9.3e-06 26.2 0.0 4.3e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GBG90227.1 - 0.0071 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 GBG90227.1 - 0.078 12.6 0.2 5.4 6.6 0.0 2.6 2 1 1 3 3 3 0 Thymidylate kinase AAA_19 PF13245.6 GBG90227.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.21 GBG90228.1 - 3.2e-213 709.7 0.4 1.3e-168 562.3 0.1 2.4 1 1 1 2 2 2 2 Myosin head (motor domain) DIL PF01843.19 GBG90228.1 - 3e-23 82.1 0.0 1.4e-22 79.9 0.0 2.3 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 GBG90228.1 - 3e-08 32.8 19.6 0.048 13.5 0.5 6.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 GBG90228.1 - 3.2e-05 23.7 2.0 6e-05 22.8 2.0 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 GBG90228.1 - 0.29 11.5 0.0 0.29 11.5 0.0 4.3 3 1 1 4 4 4 0 AAA ATPase domain Myosin_head PF00063.21 GBG90229.1 - 3.2e-213 709.8 0.4 1.3e-168 562.3 0.1 2.4 1 1 1 2 2 2 2 Myosin head (motor domain) DIL PF01843.19 GBG90229.1 - 2.9e-23 82.1 0.0 1.4e-22 79.9 0.0 2.3 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 GBG90229.1 - 2.9e-08 32.8 19.6 0.048 13.5 0.5 6.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 GBG90229.1 - 3.1e-05 23.7 2.0 6e-05 22.8 2.0 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 GBG90229.1 - 0.29 11.5 0.0 0.29 11.5 0.0 4.3 3 1 1 4 4 4 0 AAA ATPase domain Nop14 PF04147.12 GBG90230.1 - 4.7 5.3 13.3 6.7 4.8 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG90232.1 - 0.016 13.9 27.4 0.021 13.5 27.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LAP1C PF05609.12 GBG90232.1 - 0.086 11.9 11.7 0.098 11.7 11.7 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) YL1 PF05764.13 GBG90232.1 - 0.17 12.0 31.5 0.27 11.3 31.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GBG90232.1 - 0.2 11.0 28.1 0.25 10.7 28.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG90232.1 - 0.26 9.4 30.0 0.34 9.1 30.0 1.1 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.11 GBG90232.1 - 0.55 9.9 33.3 0.87 9.2 33.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop53 PF07767.11 GBG90232.1 - 0.6 9.4 27.1 0.74 9.1 27.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Lin-8 PF03353.15 GBG90232.1 - 1.4 8.4 17.6 2.1 7.8 17.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GBP_C PF02841.14 GBG90232.1 - 1.7 8.0 20.5 2.3 7.6 20.5 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain GREB1 PF15782.5 GBG90232.1 - 2.3 5.2 10.9 2.7 5.0 10.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 GBG90233.1 - 0.21 9.8 11.9 0.23 9.7 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG90233.1 - 0.25 9.5 17.5 0.29 9.3 17.5 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG90233.1 - 1.1 8.5 14.5 1.3 8.2 14.5 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 GBG90233.1 - 1.7 7.3 3.5 2.1 7.0 3.5 1.0 1 0 0 1 1 1 0 Presenilin PTPRCAP PF15713.5 GBG90233.1 - 3.8 7.8 20.6 6.4 7.1 20.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PP2C PF00481.21 GBG90234.1 - 1.1e-72 244.7 0.2 2.3e-57 194.6 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GBG90234.1 - 5.2e-05 23.0 0.1 0.0096 15.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Peptidase_C1 PF00112.23 GBG90235.1 - 1e-43 150.0 0.1 1.1e-43 149.8 0.1 1.0 1 0 0 1 1 1 1 Papain family cysteine protease PRIMA1 PF16101.5 GBG90236.1 - 0.4 10.7 14.1 1.7 8.7 14.1 2.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF659 PF04937.15 GBG90237.1 - 9.7e-15 54.7 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG90238.1 - 3.8e-22 78.8 0.0 6.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG90239.1 - 5.3e-05 23.1 0.9 9.9e-05 22.3 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Apelin PF15360.6 GBG90239.1 - 0.95 10.1 0.0 0.95 10.1 0.0 3.3 3 1 1 4 4 4 0 APJ endogenous ligand DDE_Tnp_4 PF13359.6 GBG90240.1 - 1.1e-30 106.4 0.0 2e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90240.1 - 7.3e-16 58.4 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90240.1 - 4.9e-05 23.1 0.2 0.043 13.5 0.0 2.4 2 0 0 2 2 2 2 Transposase DDE domain zf-CCHC PF00098.23 GBG90242.1 - 7.6e-08 32.1 4.0 2e-07 30.8 4.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG90242.1 - 0.031 14.3 3.3 0.074 13.0 3.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG90242.1 - 0.061 13.2 6.1 0.13 12.2 2.9 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF1682 PF07946.14 GBG90242.1 - 0.34 10.1 20.6 0.57 9.3 20.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) XRN_M PF17846.1 GBG90242.1 - 0.76 8.7 8.6 1.1 8.1 8.6 1.3 1 0 0 1 1 1 0 Xrn1 helical domain AAA_23 PF13476.6 GBG90242.1 - 0.85 10.1 9.7 0.27 11.7 6.7 1.7 2 0 0 2 2 2 0 AAA domain Zip PF02535.22 GBG90242.1 - 5.3 6.2 4.6 7.9 5.6 4.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Mem_trans PF03547.18 GBG90244.1 - 1.7e-22 79.4 15.9 9.8e-09 34.1 8.3 3.1 2 1 1 3 3 3 3 Membrane transport protein SelP_N PF04592.14 GBG90244.1 - 0.13 11.6 10.7 0.26 10.7 10.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Mem_trans PF03547.18 GBG90245.1 - 4.3e-28 97.8 20.1 2.7e-13 49.1 0.2 3.1 2 1 1 3 3 3 3 Membrane transport protein SelP_N PF04592.14 GBG90245.1 - 0.13 11.6 10.7 0.26 10.7 10.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RVT_1 PF00078.27 GBG90246.1 - 2.4e-13 50.1 0.1 3.1e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lin-8 PF03353.15 GBG90246.1 - 0.089 12.3 3.2 0.12 11.9 3.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2201_N PF13203.6 GBG90246.1 - 3.4 7.2 8.5 5.2 6.6 8.5 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.14 GBG90246.1 - 5.3 5.2 11.9 7.1 4.8 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG90246.1 - 7.6 5.9 20.1 9.3 5.6 20.1 1.1 1 0 0 1 1 1 0 SDA1 Mem_trans PF03547.18 GBG90247.1 - 1.1e-42 145.9 0.5 2.5e-26 92.0 2.9 2.1 2 0 0 2 2 2 2 Membrane transport protein DUF4618 PF15397.6 GBG90247.1 - 0.022 14.2 0.7 0.022 14.2 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Trimer_CC PF08954.11 GBG90247.1 - 0.16 11.6 6.2 0.14 11.8 1.2 3.1 2 1 1 3 3 3 0 Trimerisation motif UPF0242 PF06785.11 GBG90247.1 - 0.29 11.2 5.0 2.5 8.2 5.0 2.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MnmE_helical PF12631.7 GBG90247.1 - 1.7 8.8 6.5 2.5 8.2 5.2 1.8 2 1 0 2 2 2 0 MnmE helical domain Arm PF00514.23 GBG90248.1 - 6.1e-15 54.7 20.3 0.017 15.2 0.1 10.3 11 0 0 11 11 11 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GBG90248.1 - 0.013 15.9 18.8 0.14 12.5 4.8 4.8 5 1 0 5 5 5 0 HEAT repeats Aconitase_B_N PF11791.8 GBG90248.1 - 0.13 12.4 4.7 0.39 10.8 0.3 3.0 2 1 1 3 3 3 0 Aconitate B N-terminal domain BAF250_C PF12031.8 GBG90248.1 - 2.2 7.5 4.1 9.3 5.5 0.1 3.3 3 1 1 4 4 4 0 SWI/SNF-like complex subunit BAF250/Osa RT_RNaseH_2 PF17919.1 GBG90249.1 - 3.9e-35 119.9 0.1 7.7e-35 118.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90249.1 - 4.1e-32 111.5 0.2 6.1e-32 110.9 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG90249.1 - 3.3e-30 104.5 0.1 6.5e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FancD2 PF14631.6 GBG90250.1 - 6.3 4.0 8.6 9.7 3.4 8.6 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease FancD2 PF14631.6 GBG90251.1 - 4.1 4.7 8.4 6.3 4.1 8.4 1.3 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease zf-CCHC PF00098.23 GBG90253.1 - 7.8e-09 35.2 3.3 1.9e-08 34.0 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle GCV_H PF01597.19 GBG90254.1 - 0.028 14.3 0.0 0.039 13.9 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF5470 PF17564.2 GBG90254.1 - 0.03 14.5 2.6 0.036 14.3 1.4 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5470) TRAM_LAG1_CLN8 PF03798.16 GBG90257.1 - 3.1e-34 118.4 27.8 3.1e-34 118.4 27.8 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 GBG90257.1 - 0.0071 16.0 1.9 0.017 14.8 1.9 1.6 1 0 0 1 1 1 1 TRAM1-like protein Usp PF00582.26 GBG90257.1 - 0.42 11.1 2.1 0.85 10.1 2.1 1.4 1 0 0 1 1 1 0 Universal stress protein family ParA PF10609.9 GBG90258.1 - 2.5e-91 305.5 0.2 3.6e-82 275.5 0.2 2.1 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GBG90258.1 - 2.2e-12 47.1 0.0 4.5e-10 39.7 0.0 2.3 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GBG90258.1 - 2.9e-08 33.8 0.0 8e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 GBG90258.1 - 7.3e-08 31.9 0.2 1.1e-06 28.0 0.0 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 GBG90258.1 - 1.4e-05 24.6 0.2 0.0022 17.5 0.1 2.7 3 0 0 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 GBG90258.1 - 0.00013 21.4 0.0 0.00029 20.2 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 GBG90258.1 - 0.0038 16.7 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Glyco_hydro_3 PF00933.21 GBG90258.1 - 0.0052 16.2 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain AAA_25 PF13481.6 GBG90258.1 - 0.012 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.6 GBG90258.1 - 0.014 15.2 0.2 5.9 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 GBG90258.1 - 0.016 15.1 0.3 0.065 13.1 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 GBG90258.1 - 0.043 12.8 0.1 0.07 12.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 GBG90258.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CLP1_P PF16575.5 GBG90258.1 - 0.064 13.0 0.1 0.2 11.5 0.0 1.7 1 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 GBG90258.1 - 0.091 11.9 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain SIS_2 PF13580.6 GBG90258.1 - 0.12 12.4 0.0 23 5.0 0.0 2.8 3 0 0 3 3 3 0 SIS domain SRP54 PF00448.22 GBG90258.1 - 0.16 11.6 0.1 0.83 9.3 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ist1 PF03398.14 GBG90260.1 - 7.2e-22 78.1 0.0 1.5e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Macoilin PF09726.9 GBG90260.1 - 0.49 8.9 8.4 0.66 8.5 8.4 1.2 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 GBG90260.1 - 3.2 6.0 9.0 4.3 5.6 9.0 1.1 1 0 0 1 1 1 0 Menin Pex2_Pex12 PF04757.14 GBG90261.1 - 0.7 9.4 2.6 1.2 8.6 2.6 1.4 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Nop25 PF09805.9 GBG90261.1 - 1.5 9.3 5.2 2.2 8.7 5.2 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Presenilin PF01080.17 GBG90261.1 - 6.5 5.4 4.7 8.1 5.1 4.7 1.1 1 0 0 1 1 1 0 Presenilin zf-CCHC_6 PF15288.6 GBG90262.1 - 0.12 12.2 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 Zinc knuckle Choline_transpo PF04515.12 GBG90263.1 - 1.6e-95 320.1 34.9 1.6e-95 320.1 34.9 2.2 3 0 0 3 3 3 1 Plasma-membrane choline transporter CbtB PF09489.10 GBG90263.1 - 1.2 9.3 8.8 4.7 7.4 0.1 4.0 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtB) ThiF PF00899.21 GBG90264.1 - 2.6e-25 89.2 0.0 4.8e-25 88.3 0.0 1.4 1 1 0 1 1 1 1 ThiF family RVT_1 PF00078.27 GBG90265.1 - 1.4e-11 44.4 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) G-patch_2 PF12656.7 GBG90266.1 - 7.7e-19 67.6 0.1 7.7e-19 67.6 0.1 2.4 2 0 0 2 2 2 1 G-patch domain KN17_SH3 PF18131.1 GBG90266.1 - 5.9e-07 29.5 0.1 1.8e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain KOW PF00467.29 GBG90266.1 - 2.6e-05 24.0 0.1 0.038 14.0 0.0 3.0 2 0 0 2 2 2 2 KOW motif G-patch PF01585.23 GBG90266.1 - 0.00016 21.5 0.1 0.00016 21.5 0.1 2.2 2 0 0 2 2 2 1 G-patch domain REGB_T4 PF10715.9 GBG90266.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB RVT_1 PF00078.27 GBG90267.1 - 3.3e-28 98.7 0.1 1e-27 97.1 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90267.1 - 2.7e-18 65.8 0.2 5.5e-18 64.8 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90267.1 - 3.5e-10 40.1 0.0 1e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90267.1 - 1e-06 28.7 0.0 0.00027 20.9 0.0 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG90267.1 - 0.00095 19.4 0.0 0.0059 16.9 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein TolA_bind_tri PF16331.5 GBG90267.1 - 0.031 14.4 4.0 0.12 12.5 4.0 2.1 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF1664 PF07889.12 GBG90267.1 - 0.045 13.8 0.7 0.15 12.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) WTX PF09422.10 GBG90267.1 - 0.26 10.3 5.8 0.04 13.0 0.7 1.9 2 0 0 2 2 2 0 WTX protein MCM PF00493.23 GBG90268.1 - 3.9e-72 242.0 0.0 6.7e-72 241.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain RVT_1 PF00078.27 GBG90268.1 - 3.3e-27 95.4 0.2 6e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MCM_OB PF17207.3 GBG90268.1 - 4.3e-23 81.5 1.2 1.2e-22 80.1 1.2 1.8 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GBG90268.1 - 2.8e-16 59.7 1.8 2.8e-16 59.7 1.8 1.9 2 0 0 2 2 1 1 MCM AAA-lid domain AAA_5 PF07728.14 GBG90268.1 - 3e-07 30.5 0.0 5.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RVP_2 PF08284.11 GBG90268.1 - 2e-05 24.4 0.0 5.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Mg_chelatase PF01078.21 GBG90268.1 - 0.00015 21.2 1.0 0.27 10.6 0.0 3.3 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 GBG90268.1 - 0.051 14.2 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 MCM N-terminal domain gag-asp_proteas PF13975.6 GBG90268.1 - 0.08 13.5 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90268.1 - 0.08 13.6 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease AAA_3 PF07726.11 GBG90268.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Chromo PF00385.24 GBG90268.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain AAA_16 PF13191.6 GBG90268.1 - 0.41 11.0 4.7 0.6 10.5 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain TFIIF_alpha PF05793.12 GBG90268.1 - 0.62 8.6 4.8 1.4 7.4 4.8 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SR-25 PF10500.9 GBG90268.1 - 1.1 8.9 6.8 3.6 7.2 6.8 1.9 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 GBG90269.1 - 6.7e-27 94.5 0.1 1.2e-26 93.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG90269.1 - 2.1e-06 28.3 0.0 4.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG90269.1 - 7.1e-06 25.8 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG90269.1 - 1.2e-05 25.8 0.0 2.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG90269.1 - 2.5e-05 24.4 1.6 6.2e-05 23.2 0.1 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG90269.1 - 0.0031 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG90270.1 - 1.5e-22 80.2 0.1 3.6e-22 79.0 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG90270.1 - 1e-07 32.4 0.0 3.4e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90270.1 - 3.4e-06 27.6 0.0 8.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG90270.1 - 7e-06 25.9 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG90270.1 - 9.8e-05 22.1 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG90270.1 - 0.012 15.9 2.7 0.015 15.6 0.2 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Ntox1 PF15500.6 GBG90270.1 - 1.5 9.2 4.2 13 6.2 4.2 2.6 1 1 0 1 1 1 0 Putative RNase-like toxin, toxin_1 RVT_1 PF00078.27 GBG90271.1 - 3.3e-31 108.5 0.0 6.1e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG90271.1 - 0.0035 18.0 0.0 0.014 16.0 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Kinesin PF00225.23 GBG90272.1 - 1.6e-28 99.6 0.0 7e-28 97.5 0.0 1.9 1 1 0 1 1 1 1 Kinesin motor domain Integrase_H2C2 PF17921.1 GBG90274.1 - 1.2e-09 38.1 0.1 4.5e-09 36.3 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG90274.1 - 2.2e-09 37.2 0.0 4.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90274.1 - 1.2e-06 28.7 0.0 4e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG90274.1 - 0.076 13.2 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG90275.1 - 3.4e-15 56.1 0.0 6.7e-15 55.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90275.1 - 4.8e-06 26.3 0.0 7.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DUF659 PF04937.15 GBG90276.1 - 1.5e-06 28.2 0.0 2.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CENP-S PF15630.6 GBG90277.1 - 0.044 14.2 0.1 0.057 13.8 0.1 1.1 1 0 0 1 1 1 0 CENP-S protein Collectrin PF16959.5 GBG90277.1 - 0.072 12.9 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Renal amino acid transporter Vasculin PF15337.6 GBG90278.1 - 0.024 15.5 0.3 0.081 13.8 0.1 1.9 1 1 1 2 2 2 0 Vascular protein family Vasculin-like 1 WAP PF00095.21 GBG90279.1 - 1.1 9.7 27.7 0.51 10.8 19.1 2.3 1 1 1 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' RVT_1 PF00078.27 GBG90281.1 - 4.5e-28 98.3 0.1 8e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Endotoxin_N PF03945.14 GBG90281.1 - 0.016 14.9 4.6 2.4 7.8 0.1 3.5 2 1 0 3 3 3 0 delta endotoxin, N-terminal domain Baculo_PEP_C PF04513.12 GBG90281.1 - 0.27 11.3 2.9 0.73 9.9 2.9 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SDA1 PF05285.12 GBG90284.1 - 0.003 17.0 0.7 0.003 17.0 0.7 1.1 1 0 0 1 1 1 1 SDA1 DUF4637 PF15470.6 GBG90284.1 - 0.24 11.1 6.1 0.37 10.5 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TRAP_alpha PF03896.16 GBG90284.1 - 0.82 8.8 3.3 6.6 5.9 4.3 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 GBG90284.1 - 1.2 8.5 8.1 1.5 8.2 8.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 GBG90284.1 - 1.2 7.2 7.0 1.4 7.0 7.0 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG90284.1 - 1.4 7.1 4.1 1.7 6.9 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG90284.1 - 1.6 6.8 9.2 2 6.4 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi peroxidase PF00141.23 GBG90285.1 - 1.2e-38 133.0 0.1 2e-37 129.1 0.1 2.0 1 1 0 1 1 1 1 Peroxidase peroxidase PF00141.23 GBG90286.1 - 2e-41 142.2 0.1 2.5e-41 141.8 0.1 1.1 1 0 0 1 1 1 1 Peroxidase peroxidase PF00141.23 GBG90287.1 - 1.2e-38 133.0 0.1 2e-37 129.1 0.1 2.0 1 1 0 1 1 1 1 Peroxidase zf-CCHC PF00098.23 GBG90288.1 - 1.8e-08 34.1 1.3 3e-08 33.4 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG90288.1 - 2.9e-05 23.8 0.8 4.9e-05 23.1 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle peroxidase PF00141.23 GBG90290.1 - 1.5e-41 142.6 0.0 1.9e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase SMAP PF15477.6 GBG90292.1 - 5.3e-13 49.7 1.3 5.3e-13 49.7 1.3 3.8 4 0 0 4 4 4 1 Small acidic protein family RT_RNaseH_2 PF17919.1 GBG90293.1 - 6.3e-31 106.4 0.0 2.4e-29 101.3 0.0 3.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90293.1 - 2.2e-30 105.0 0.1 4e-29 101.0 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90293.1 - 1.3e-19 70.0 0.4 3.1e-19 68.8 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90293.1 - 2.8e-15 56.5 0.0 9.2e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90293.1 - 0.0017 18.5 0.1 0.0053 17.0 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG90293.1 - 0.06 13.0 0.0 0.06 13.0 0.0 3.1 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Presenilin PF01080.17 GBG90293.1 - 0.23 10.2 3.2 0.4 9.4 3.2 1.3 1 0 0 1 1 1 0 Presenilin GYF_2 PF14237.6 GBG90294.1 - 1.1e-14 53.9 1.9 3.3e-14 52.4 1.9 1.9 1 0 0 1 1 1 1 GYF domain 2 RRM_1 PF00076.22 GBG90294.1 - 1.9e-14 53.2 0.0 3.5e-06 26.7 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GYF PF02213.16 GBG90294.1 - 8e-07 28.6 1.3 1.6e-06 27.6 1.3 1.6 1 0 0 1 1 1 1 GYF domain RRM_7 PF16367.5 GBG90294.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RVT_1 PF00078.27 GBG90295.1 - 5e-22 78.5 0.0 7.7e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RecO_C PF02565.15 GBG90295.1 - 0.034 13.9 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 Recombination protein O C terminal APG5 PF04106.12 GBG90296.1 - 1.1e-21 77.5 0.0 2.9e-11 43.4 0.1 3.0 3 0 0 3 3 3 2 Autophagy protein Apg5 DDE_1 PF03184.19 GBG90296.1 - 1.2e-10 41.3 0.2 2.8e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-UBR PF02207.20 GBG90297.1 - 2.6e-12 46.7 7.0 2.6e-12 46.7 7.0 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 GBG90297.1 - 2.9e-06 27.1 4.0 2.9e-06 27.1 4.0 3.7 3 1 1 4 4 4 1 PHD-finger Antifungal_pept PF11410.8 GBG90297.1 - 3.8 7.5 11.9 0.12 12.3 0.5 3.7 3 0 0 3 3 3 0 Antifungal peptide Ribosomal_S5_C PF03719.15 GBG90298.1 - 3.7e-25 87.2 0.3 2.7e-24 84.4 0.1 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 GBG90298.1 - 1.3e-23 82.7 1.1 3.1e-23 81.5 1.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain NatB_MDM20 PF09797.9 GBG90299.1 - 2e-53 181.7 0.0 2e-53 181.7 0.0 1.9 3 0 0 3 3 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 GBG90299.1 - 5e-11 42.5 6.1 0.0028 18.3 0.1 7.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG90299.1 - 3.2e-09 36.2 0.5 0.001 19.0 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG90299.1 - 7e-09 35.1 1.9 0.11 12.6 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG90299.1 - 9.2e-09 35.7 3.6 0.00047 20.6 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG90299.1 - 1.4e-08 34.3 0.2 0.052 13.8 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GBG90299.1 - 5.1e-08 33.1 1.8 0.0061 16.8 0.0 5.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG90299.1 - 1.3e-07 31.2 0.2 0.0064 16.3 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG90299.1 - 2.4e-05 24.5 0.3 0.0048 17.1 0.1 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GBG90299.1 - 2.6e-05 23.6 2.5 2.6e-05 23.6 2.5 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 GBG90299.1 - 9.2e-05 21.5 0.5 0.0037 16.3 0.0 3.4 3 0 0 3 3 2 2 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 GBG90299.1 - 0.00019 21.2 0.1 0.097 12.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_5 PF12688.7 GBG90299.1 - 0.025 14.8 0.4 0.23 11.7 0.1 2.9 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_16 PF13432.6 GBG90299.1 - 0.025 15.2 9.8 8.4 7.1 0.0 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GBG90299.1 - 0.09 12.2 0.5 0.24 10.7 0.5 1.7 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_6 PF13174.6 GBG90299.1 - 0.097 13.4 1.3 96 4.0 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GBG90299.1 - 0.15 11.8 0.1 23 4.8 0.0 3.6 4 0 0 4 4 4 0 TPR repeat EphA2_TM PF14575.6 GBG90299.1 - 0.28 12.1 0.6 1.6 9.7 0.6 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain V_ATPase_I PF01496.19 GBG90299.1 - 0.91 7.4 4.5 1.8 6.3 4.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2615 PF11027.8 GBG90299.1 - 2 8.6 5.0 0.23 11.6 0.3 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2615) Presenilin PF01080.17 GBG90299.1 - 5.1 5.8 11.3 8.4 5.0 11.3 1.3 1 0 0 1 1 1 0 Presenilin E3_UbLigase_RBR PF18091.1 GBG90300.1 - 0.26 11.5 2.3 0.29 11.3 0.1 2.1 2 0 0 2 2 2 0 E3 Ubiquitin Ligase RBR C-terminal domain DUF4913 PF16259.5 GBG90301.1 - 0.0066 16.5 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4913) CEP63 PF17045.5 GBG90301.1 - 0.017 15.0 0.5 0.024 14.6 0.5 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa betaPIX_CC PF16523.5 GBG90302.1 - 0.048 13.5 1.0 0.048 13.5 1.0 2.6 2 0 0 2 2 2 0 betaPIX coiled coil YscO-like PF16789.5 GBG90302.1 - 1.2 9.2 18.8 0.05 13.6 1.3 2.2 2 0 0 2 2 2 0 YscO-like protein DUF4164 PF13747.6 GBG90302.1 - 1.7 8.9 14.4 1.9 8.8 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DEK_C PF08766.11 GBG90304.1 - 0.028 14.3 0.1 0.079 12.9 0.1 1.8 1 0 0 1 1 1 0 DEK C terminal domain zf-nanos PF05741.13 GBG90304.1 - 1.4 9.3 4.1 1.4e+02 2.8 0.0 4.4 4 0 0 4 4 4 0 Nanos RNA binding domain Pkinase PF00069.25 GBG90307.1 - 4.6e-21 75.4 0.0 7.3e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG90307.1 - 1.4e-18 67.1 0.0 2.4e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GBG90307.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.15 GBG90307.1 - 0.037 13.8 4.3 0.066 13.0 4.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.6 GBG90307.1 - 0.042 14.1 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Trypan_PARP PF05887.11 GBG90307.1 - 0.052 13.5 10.0 0.082 12.9 10.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Herpes_gE PF02480.16 GBG90307.1 - 0.11 11.3 0.2 0.15 10.8 0.2 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_15_3 PF03307.14 GBG90308.1 - 0.23 11.4 3.0 5.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region GIT_CC PF16559.5 GBG90308.1 - 3.7 7.5 8.9 3.7 7.5 0.8 3.2 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Pkinase_Tyr PF07714.17 GBG90309.1 - 4.4e-55 186.7 0.0 1e-34 120.0 0.0 3.5 2 2 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 GBG90309.1 - 1e-53 182.4 0.0 1.9e-33 116.0 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain RT_RNaseH PF17917.1 GBG90309.1 - 6.3e-31 106.8 0.0 2.8e-24 85.4 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90309.1 - 4.4e-27 94.0 0.0 3.1e-25 88.1 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90309.1 - 1.8e-11 44.0 0.1 3.7e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.23 GBG90309.1 - 0.0038 17.2 0.0 1.5 8.7 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Myb_DNA-bind_4 PF13837.6 GBG90309.1 - 0.0083 16.5 0.3 0.022 15.1 0.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain EphA2_TM PF14575.6 GBG90309.1 - 0.04 14.8 0.1 11 7.0 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 GBG90309.1 - 0.12 12.6 0.0 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator LapA_dom PF06305.11 GBG90309.1 - 4.1 7.3 6.5 11 6.0 0.4 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pkinase_Tyr PF07714.17 GBG90311.1 - 2.5e-36 125.3 0.0 1.1e-35 123.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90311.1 - 6.2e-32 111.0 0.0 9e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Trypan_PARP PF05887.11 GBG90311.1 - 0.00052 20.0 1.4 0.001 19.1 1.4 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) APH PF01636.23 GBG90311.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CEND1 PF15677.5 GBG90311.1 - 0.087 13.4 1.5 0.14 12.7 1.5 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 SKG6 PF08693.10 GBG90311.1 - 0.54 9.7 9.3 0.96 8.9 9.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LapA_dom PF06305.11 GBG90311.1 - 0.78 9.6 2.1 1.5 8.7 2.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase_Tyr PF07714.17 GBG90312.1 - 2.1e-27 96.1 0.0 2.8e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90312.1 - 3.1e-22 79.2 0.0 4.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RXLR PF16810.5 GBG90314.1 - 0.18 12.2 4.2 0.98 9.8 1.8 2.4 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity GOLD_2 PF13897.6 GBG90314.1 - 0.86 10.1 3.8 1.9 9.0 3.8 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FAM176 PF14851.6 GBG90314.1 - 4.6 6.9 6.3 12 5.6 6.3 1.6 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 GBG90314.1 - 4.9 6.9 10.0 12 5.6 10.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 GBG90314.1 - 6.7 4.9 6.4 9.5 4.4 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG90315.1 - 7.8e-30 102.9 0.0 1.1e-14 54.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90315.1 - 1.3e-27 96.1 0.0 3.1e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90315.1 - 1.8e-26 93.0 0.1 3e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90315.1 - 1.1e-10 41.4 0.7 4.1e-10 39.6 0.7 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90315.1 - 9.4e-10 38.7 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG90315.1 - 2.5e-08 33.6 1.5 8e-08 32.0 1.5 2.0 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG90315.1 - 6.1e-07 29.9 0.0 3.6e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90315.1 - 1.4e-06 28.8 0.0 0.0014 19.3 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG90315.1 - 7.2e-05 22.6 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GBG90315.1 - 0.00062 19.5 2.0 0.0024 17.7 2.0 2.1 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 GBG90315.1 - 0.0087 15.9 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF659 PF04937.15 GBG90316.1 - 0.046 13.6 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG90317.1 - 2.8e-36 125.1 0.1 5.7e-36 124.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG90317.1 - 2.1e-27 95.5 0.1 5.6e-27 94.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90317.1 - 2.5e-26 91.6 0.0 6.6e-26 90.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Es2 PF09751.9 GBG90317.1 - 0.0099 15.7 15.2 0.016 15.0 15.2 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 Integrase_H2C2 PF17921.1 GBG90318.1 - 8.7e-13 48.2 0.3 2.1e-12 47.0 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90318.1 - 1.9e-11 44.2 0.0 5.7e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG90318.1 - 3.8e-09 36.4 0.0 7.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PriC PF07445.12 GBG90318.1 - 0.62 10.0 3.3 0.54 10.2 1.2 1.9 2 0 0 2 2 2 0 Primosomal replication protein priC RVT_1 PF00078.27 GBG90319.1 - 5.3e-28 98.0 0.0 8.7e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1995 PF09353.10 GBG90319.1 - 2.5e-08 34.2 0.0 2.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1995) RT_RNaseH PF17917.1 GBG90321.1 - 6.1e-29 100.4 0.0 1.4e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90321.1 - 1.8e-22 79.3 0.0 4.4e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90321.1 - 1.5e-19 69.8 0.3 3.2e-19 68.8 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG90321.1 - 0.00022 21.4 0.0 0.00053 20.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG90321.1 - 0.19 11.3 2.7 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG90322.1 - 6.3e-29 101.1 0.1 1e-28 100.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90322.1 - 3.1e-27 94.5 0.0 1.3e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90322.1 - 7.3e-26 90.5 0.0 2.2e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG90322.1 - 3.9e-07 30.6 0.0 1e-06 29.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90322.1 - 2.7e-06 27.9 0.0 6.4e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG90322.1 - 9e-06 25.5 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG90322.1 - 0.00043 20.1 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1995 PF09353.10 GBG90323.1 - 9.7e-22 78.0 0.4 8e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1995) Chromo PF00385.24 GBG90323.1 - 0.00019 21.2 0.2 0.00046 20.0 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 GBG90323.1 - 0.0046 17.2 2.3 0.0064 16.7 0.3 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG90323.1 - 0.0084 15.9 0.9 0.022 14.5 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RVT_1 PF00078.27 GBG90325.1 - 4.8e-20 72.0 0.1 8.6e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG90325.1 - 4.7e-08 32.9 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90325.1 - 5.3e-07 30.2 0.0 1.6e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90325.1 - 3.5e-05 24.3 0.0 0.00026 21.5 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG90325.1 - 0.0062 16.8 0.2 0.021 15.1 0.2 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG90325.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 GBG90326.1 - 3.5e-31 107.6 0.0 8.6e-31 106.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90326.1 - 9.9e-31 105.7 0.0 2.2e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90326.1 - 2.8e-09 36.9 0.0 8.5e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG90326.1 - 0.00044 20.5 0.1 0.0024 18.1 0.1 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG90326.1 - 0.0032 17.0 0.1 0.0068 15.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG90326.1 - 0.1 12.2 0.0 0.1 12.2 0.0 2.9 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Tubulin_3 PF14881.6 GBG90326.1 - 1.9 8.1 5.2 0.34 10.6 0.1 2.4 3 0 0 3 3 3 0 Tubulin domain RVT_1 PF00078.27 GBG90327.1 - 3e-21 76.0 0.1 5.2e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90327.1 - 1.7e-18 66.4 0.7 5.9e-18 64.7 0.2 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG90327.1 - 1.1e-13 51.0 0.0 2.8e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90327.1 - 9.5e-10 38.7 0.3 4.3e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG90327.1 - 9.9e-09 35.4 0.0 0.00011 22.4 0.0 2.9 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG90327.1 - 0.0069 17.0 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90327.1 - 0.032 14.8 0.0 0.061 13.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG90327.1 - 0.044 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-HC2 PF13490.6 GBG90327.1 - 0.1 12.8 0.6 0.61 10.4 0.6 2.5 1 0 0 1 1 1 0 Putative zinc-finger Asp_protease PF09668.10 GBG90327.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Snapin_Pallidin PF14712.6 GBG90327.1 - 1.5 9.3 10.9 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 Snapin/Pallidin DUF659 PF04937.15 GBG90328.1 - 1.8e-18 66.9 0.0 2.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90328.1 - 0.001 18.8 0.1 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH_2 PF17919.1 GBG90330.1 - 2.6e-28 98.0 0.0 6.2e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90330.1 - 2.2e-25 89.0 0.0 3.9e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90330.1 - 1.1e-14 54.3 0.0 3.1e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG90330.1 - 3.1e-11 43.2 0.2 5.5e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90330.1 - 1.8e-10 41.1 0.0 4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90330.1 - 0.014 15.6 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Rhamno_transf PF11316.8 GBG90330.1 - 0.093 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative rhamnosyl transferase Integrase_H2C2 PF17921.1 GBG90331.1 - 5.8e-20 71.2 0.0 1.1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90331.1 - 3.1e-18 66.0 0.2 7.8e-18 64.7 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90331.1 - 4.6e-10 39.4 0.0 1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG90331.1 - 0.00026 21.1 0.0 0.00067 19.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG90331.1 - 0.0083 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG90331.1 - 0.0089 15.7 1.6 0.023 14.4 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) Integrase_H2C2 PF17921.1 GBG90332.1 - 9e-17 60.9 0.6 1.7e-16 60.0 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90332.1 - 3.4e-08 33.7 0.0 9.6e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG90332.1 - 1.7e-07 31.0 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG90332.1 - 2e-07 30.8 0.2 4.1e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG90332.1 - 1.6e-06 28.7 0.0 3.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90332.1 - 5.4e-05 23.7 0.0 0.00012 22.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG90332.1 - 0.043 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG90332.1 - 0.067 13.4 0.1 0.39 11.0 0.2 2.2 2 0 0 2 2 2 0 H2C2 zinc finger RT_RNaseH PF17917.1 GBG90333.1 - 6.5e-27 93.9 0.5 1.2e-26 93.1 0.5 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90333.1 - 1.7e-21 76.1 0.1 3e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90333.1 - 8.6e-16 57.8 0.1 2.2e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG90333.1 - 1.2e-15 57.7 0.1 2.7e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DUF2862 PF11061.8 GBG90333.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) RT_RNaseH_2 PF17919.1 GBG90336.1 - 4.4e-53 177.5 0.0 2.4e-29 101.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90336.1 - 2.4e-48 162.8 0.0 1.1e-26 93.2 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90336.1 - 2.2e-18 66.1 0.1 6.5e-18 64.6 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG90336.1 - 1.6e-17 63.8 0.0 3.2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90336.1 - 4.4e-06 26.9 0.0 2.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG90336.1 - 0.00048 20.6 0.0 0.0015 19.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG90336.1 - 0.0038 17.4 0.0 0.0091 16.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 GBG90336.1 - 0.015 15.1 0.2 0.069 13.0 0.1 2.1 2 0 0 2 2 2 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG90336.1 - 0.035 14.7 0.0 0.094 13.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG90336.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1664 PF07889.12 GBG90336.1 - 1.3 9.1 3.9 8.1 6.5 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) RT_RNaseH PF17917.1 GBG90337.1 - 3.4e-29 101.2 0.0 7.3e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90337.1 - 2.1e-27 95.1 0.0 4.5e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90337.1 - 5.3e-19 68.1 0.8 1.7e-18 66.5 0.8 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG90337.1 - 1.1e-14 54.6 0.0 3.4e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90337.1 - 0.0032 17.7 0.1 0.0085 16.3 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG90337.1 - 0.35 10.5 0.0 0.35 10.5 0.0 2.8 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG90338.1 - 6e-28 96.8 0.0 1.6e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90338.1 - 4.4e-17 62.3 0.0 1.1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MULE PF10551.9 GBG90338.1 - 2.3e-14 53.6 0.0 8.2e-14 51.8 0.0 2.1 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG90338.1 - 2.8e-14 52.8 0.0 1.7e-13 50.3 0.0 2.4 2 0 0 2 2 2 1 MuDR family transposase RVT_1 PF00078.27 GBG90338.1 - 3.6e-12 46.3 0.1 6.4e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_mut PF00872.18 GBG90338.1 - 1e-05 24.6 0.0 2.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.17 GBG90338.1 - 0.00016 21.3 2.8 0.00038 20.0 2.8 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-CCHC_2 PF13696.6 GBG90338.1 - 0.6 10.0 3.9 0.27 11.1 0.7 2.1 2 0 0 2 2 2 0 Zinc knuckle AT_hook PF02178.19 GBG90338.1 - 0.79 9.8 4.0 2 8.6 4.0 1.7 1 0 0 1 1 1 0 AT hook motif Peptidase_C1 PF00112.23 GBG90340.1 - 3.5e-21 76.3 0.1 6.3e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GBG90340.1 - 4.5e-09 36.6 0.5 8.1e-09 35.8 0.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Apolipoprotein PF01442.18 GBG90341.1 - 0.0018 18.1 19.4 0.12 12.3 13.0 2.0 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GBG90341.1 - 0.024 15.2 18.6 0.73 10.5 7.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GBG90341.1 - 0.061 13.9 23.1 0.96 10.0 4.8 3.3 1 1 2 3 3 3 0 YtxH-like protein Mitofilin PF09731.9 GBG90341.1 - 0.28 10.0 21.0 0.32 9.8 21.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein rRNA_processing PF08524.11 GBG90341.1 - 0.63 10.1 22.6 0.85 9.6 22.6 1.2 1 0 0 1 1 1 0 rRNA processing His_Phos_1 PF00300.22 GBG90341.1 - 0.67 9.6 7.0 0.94 9.1 7.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) BshC PF10079.9 GBG90341.1 - 1.3 7.7 9.2 1.4 7.5 9.2 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DHR10 PF18595.1 GBG90341.1 - 1.6 8.8 31.8 0.33 11.0 9.1 3.5 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain MAJIN PF15077.6 GBG90341.1 - 3 7.6 10.8 3.4 7.4 10.8 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF3584 PF12128.8 GBG90341.1 - 4.9 4.5 17.3 5.2 4.5 17.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 GBG90341.1 - 5.4 7.1 12.9 6.8 6.7 12.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 GBG90341.1 - 8 5.4 8.9 9.4 5.2 8.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Podoplanin PF05808.11 GBG90341.1 - 8.9 6.4 8.2 11 6.1 8.2 1.1 1 0 0 1 1 1 0 Podoplanin BAF1_ABF1 PF04684.13 GBG90341.1 - 9.1 5.2 13.5 10 5.0 13.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Apolipoprotein PF01442.18 GBG90342.1 - 0.00025 21.0 10.7 0.00041 20.3 10.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GBG90342.1 - 0.035 14.7 12.5 0.38 11.4 6.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GBG90342.1 - 0.09 13.3 11.9 97 3.6 11.9 2.2 1 1 0 1 1 1 0 YtxH-like protein Mitofilin PF09731.9 GBG90342.1 - 0.25 10.2 11.9 0.27 10.0 11.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein rRNA_processing PF08524.11 GBG90342.1 - 1 9.4 14.1 1.2 9.2 14.1 1.1 1 0 0 1 1 1 0 rRNA processing DUF3584 PF12128.8 GBG90342.1 - 2.6 5.4 9.9 2.8 5.3 9.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HisKA_3 PF07730.13 GBG90342.1 - 5.2 7.7 7.8 23 5.6 2.9 2.5 1 1 2 3 3 3 0 Histidine kinase DUF4230 PF14014.6 GBG90342.1 - 5.6 7.2 8.1 6.3 7.1 7.9 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) XRN_M PF17846.1 GBG90342.1 - 9.5 5.0 6.4 9.8 5.0 6.4 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DBD_Tnp_Mut PF03108.15 GBG90343.1 - 0.0037 17.2 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 MuDR family transposase REV PF00424.18 GBG90344.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.5 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF3138 PF11336.8 GBG90344.1 - 0.26 9.9 2.9 0.29 9.7 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) Apolipoprotein PF01442.18 GBG90345.1 - 0.0033 17.3 7.9 0.0042 17.0 7.9 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mitofilin PF09731.9 GBG90345.1 - 0.028 13.3 8.4 0.032 13.1 8.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF883 PF05957.13 GBG90345.1 - 0.063 13.9 8.5 0.44 11.2 6.5 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GBG90345.1 - 0.2 12.2 9.9 19 5.8 9.9 2.1 1 1 0 1 1 1 0 YtxH-like protein LEA_1 PF03760.15 GBG90345.1 - 0.31 11.7 24.0 0.98 10.1 18.3 2.2 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 Ax_dynein_light PF10211.9 GBG90345.1 - 0.5 10.3 7.9 0.52 10.2 7.9 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain EMC3_TMCO1 PF01956.16 GBG90345.1 - 7.6 6.2 6.7 8.2 6.1 6.7 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RT_RNaseH_2 PF17919.1 GBG90346.1 - 3.2e-32 110.5 0.0 5.9e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90346.1 - 2.3e-31 108.2 0.0 4.3e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90346.1 - 1.4e-13 50.9 0.1 2.8e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG90346.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Pkinase_Tyr PF07714.17 GBG90347.1 - 3.5e-37 128.1 0.0 8e-37 126.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90347.1 - 4.8e-36 124.5 0.0 7.7e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG90347.1 - 0.0075 16.2 0.1 0.017 15.0 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG90347.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RT_RNaseH_2 PF17919.1 GBG90348.1 - 2.3e-33 114.2 0.0 4.5e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90348.1 - 1.1e-27 96.4 0.0 2e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90348.1 - 4.5e-10 39.4 0.0 7.7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG90348.1 - 0.12 12.7 0.0 0.38 11.1 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein DUF5095 PF17016.5 GBG90348.1 - 0.17 11.5 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) DUF454 PF04304.13 GBG90348.1 - 0.19 11.7 0.1 5.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF454) TPPK_C PF12555.8 GBG90349.1 - 0.011 15.7 5.1 0.021 14.8 5.1 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal EphA2_TM PF14575.6 GBG90349.1 - 3.2 8.7 4.1 2 9.4 1.3 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 GBG90349.1 - 4.1 8.4 4.4 3.2 8.8 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 GBG90350.1 - 4.3e-36 124.6 0.0 6.9e-36 124.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG90350.1 - 4.9e-36 124.3 2.6 7.7e-26 90.9 0.0 2.5 1 1 0 2 2 2 2 Protein tyrosine kinase LysM PF01476.20 GBG90350.1 - 1.1e-09 38.2 0.1 3.8e-06 26.8 0.1 3.2 3 0 0 3 3 3 2 LysM domain PIP49_C PF12260.8 GBG90350.1 - 0.011 15.4 0.2 0.022 14.4 0.0 1.5 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 APH PF01636.23 GBG90350.1 - 0.044 13.7 0.2 7 6.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family GRP PF07172.11 GBG90350.1 - 6.5 7.5 27.6 0.69 10.6 7.3 2.6 2 0 0 2 2 2 0 Glycine rich protein family SKG6 PF08693.10 GBG90350.1 - 9.8 5.7 14.7 6.6 6.2 12.2 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Fasciclin PF02469.22 GBG90351.1 - 8.8e-10 38.9 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 GBG90352.1 - 2.7e-10 40.5 0.0 3.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 GBG90353.1 - 4.1e-09 36.7 0.0 6.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain EPO_TPO PF00758.18 GBG90353.1 - 0.059 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin DUF4179 PF13786.6 GBG90353.1 - 0.12 12.8 0.1 0.27 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Fasciclin PF02469.22 GBG90354.1 - 2.8e-08 34.0 0.0 4.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain zf-CCHC PF00098.23 GBG90355.1 - 4.9e-06 26.4 1.6 8.4e-06 25.6 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle LAP1C PF05609.12 GBG90355.1 - 0.049 12.7 12.7 0.029 13.5 10.9 1.4 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) zf-CCHC_4 PF14392.6 GBG90355.1 - 0.73 9.6 3.3 0.55 10.0 1.1 1.9 2 0 0 2 2 2 0 Zinc knuckle MtmB PF05369.12 GBG90356.1 - 0.17 10.7 5.3 0.21 10.4 5.3 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB DUF659 PF04937.15 GBG90357.1 - 1.2e-28 99.9 0.0 2.3e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) FYDLN_acid PF09538.10 GBG90357.1 - 0.0029 18.3 17.9 0.0067 17.1 17.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 GBG90357.1 - 0.011 14.0 28.1 0.015 13.6 28.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG90357.1 - 0.041 12.2 18.0 0.053 11.8 18.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG90357.1 - 0.089 11.5 4.6 0.12 11.2 4.6 1.1 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 GBG90357.1 - 0.17 11.2 29.0 0.25 10.8 29.0 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 GBG90357.1 - 0.19 10.5 6.8 0.25 10.1 6.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5523 PF17661.1 GBG90357.1 - 0.32 10.7 20.7 0.48 10.1 20.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Vfa1 PF08432.10 GBG90357.1 - 1.1 9.5 12.1 1.8 8.9 12.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.12 GBG90357.1 - 1.2 7.5 29.2 1.7 7.0 29.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Autophagy_N PF03986.13 GBG90357.1 - 1.4 8.9 14.1 3.1 7.8 14.1 1.5 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF2151 PF10221.9 GBG90357.1 - 1.9 7.0 7.7 2.6 6.5 7.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator TRAP_alpha PF03896.16 GBG90357.1 - 2.6 7.2 16.7 4.9 6.3 16.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF913 PF06025.12 GBG90357.1 - 2.7 6.9 7.0 3.8 6.4 7.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 GBG90357.1 - 2.8 8.3 7.6 4.9 7.6 7.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 GBG90357.1 - 3.1 7.2 10.5 4.7 6.6 10.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pes-10 PF07149.11 GBG90357.1 - 5.8 5.9 24.3 9.8 5.1 24.3 1.3 1 0 0 1 1 1 0 Pes-10 RR_TM4-6 PF06459.12 GBG90357.1 - 7.2 6.4 15.8 10 5.8 15.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MDM10 PF12519.8 GBG90357.1 - 7.5 5.3 5.1 10 4.8 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4746 PF15928.5 GBG90357.1 - 7.8 5.8 22.3 13 5.1 22.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) zf-CCHC PF00098.23 GBG90358.1 - 2.6e-07 30.4 4.6 4.8e-07 29.6 4.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG90358.1 - 0.084 12.7 1.5 0.28 11.1 1.5 1.9 1 0 0 1 1 1 0 Zinc knuckle MCM3AP_GANP PF16769.5 GBG90358.1 - 1.7 6.8 11.0 2.1 6.5 11.0 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP RVT_1 PF00078.27 GBG90359.1 - 2.7e-16 59.8 0.0 5.5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90359.1 - 1.3e-09 37.9 0.0 3.6e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG90359.1 - 0.00081 19.6 4.0 0.0013 19.0 0.0 3.2 4 0 0 4 4 4 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG90359.1 - 0.015 15.6 0.2 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Seryl_tRNA_N PF02403.22 GBG90359.1 - 0.086 13.1 0.3 0.086 13.1 0.3 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Matrilin_ccoil PF10393.9 GBG90359.1 - 0.35 10.8 3.6 2.1 8.3 0.5 3.1 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin SlyX PF04102.12 GBG90359.1 - 0.67 10.6 4.2 1.1 10.0 1.2 2.8 3 0 0 3 3 3 0 SlyX MFAP1 PF06991.11 GBG90359.1 - 1.6 8.5 8.5 3 7.6 8.5 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DDE_Tnp_4 PF13359.6 GBG90360.1 - 4.4e-11 42.7 0.4 7.1e-10 38.8 0.0 2.4 2 1 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90360.1 - 0.00071 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Pkinase PF00069.25 GBG90361.1 - 4.9e-27 94.9 0.0 8e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG90361.1 - 2.8e-16 59.6 0.0 3.9e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG90361.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TMEM208_SND2 PF05620.11 GBG90361.1 - 0.068 12.9 1.4 0.12 12.1 1.4 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Pkinase_Tyr PF07714.17 GBG90363.1 - 8.3e-26 90.8 0.0 7e-18 64.8 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG90363.1 - 1.1e-18 67.6 0.0 7.7e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain TMEM154 PF15102.6 GBG90363.1 - 0.091 12.7 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Pkinase_Tyr PF07714.17 GBG90365.1 - 4.2e-33 114.7 0.0 1.7e-32 112.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90365.1 - 2.9e-31 108.8 0.0 7.6e-31 107.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain GRP PF07172.11 GBG90365.1 - 0.00069 20.2 12.7 0.00069 20.2 12.7 3.5 3 0 0 3 3 3 1 Glycine rich protein family RRN3 PF05327.11 GBG90365.1 - 0.19 10.3 0.9 0.39 9.2 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spem1 PF15670.5 GBG90365.1 - 6.5 6.3 7.5 13 5.3 7.5 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 Adeno_terminal PF02459.15 GBG90365.1 - 9.4 4.5 11.7 18 3.6 11.7 1.4 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Pkinase_Tyr PF07714.17 GBG90366.1 - 1.9e-34 119.2 0.0 2.6e-33 115.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90366.1 - 6.9e-33 114.1 0.0 1.3e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG90366.1 - 8.7e-22 77.0 0.0 1.7e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90366.1 - 1.8e-21 76.3 0.0 3.8e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90366.1 - 2.8e-10 40.1 0.1 5.2e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SMN PF06003.12 GBG90373.1 - 0.042 13.1 0.1 0.079 12.2 0.1 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) WD40 PF00400.32 GBG90375.1 - 1.4e-05 25.8 18.1 0.091 13.7 0.2 6.8 6 1 0 6 6 6 2 WD domain, G-beta repeat PQQ_3 PF13570.6 GBG90375.1 - 0.18 12.3 9.9 1.3 9.6 0.1 5.2 3 2 2 5 5 5 0 PQQ-like domain SNARE PF05739.19 GBG90376.1 - 5e-06 26.4 1.4 1.3e-05 25.1 1.4 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 GBG90376.1 - 0.0019 17.9 8.2 0.079 12.6 2.0 2.3 2 0 0 2 2 2 2 Syntaxin MCPsignal PF00015.21 GBG90376.1 - 0.059 13.2 0.8 0.12 12.1 0.2 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2203 PF09969.9 GBG90376.1 - 0.15 12.7 1.8 1.5 9.5 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Exo_endo_phos PF03372.23 GBG90376.1 - 0.19 11.2 1.2 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Syntaxin_2 PF14523.6 GBG90376.1 - 0.26 11.7 4.5 0.16 12.3 0.5 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Apocytochr_F_C PF01333.19 GBG90376.1 - 7.1 6.7 6.0 1.6 8.8 1.7 2.1 2 0 0 2 2 2 0 Apocytochrome F, C-terminal Glycos_transf_2 PF00535.26 GBG90377.1 - 1.9e-33 115.6 0.0 2.3e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG90377.1 - 2.5e-16 60.3 0.0 2.9e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GBG90377.1 - 1.5e-05 24.6 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GBG90377.1 - 5.1e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF4471 PF14740.6 GBG90377.1 - 0.067 12.4 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) CwfJ_C_1 PF04677.15 GBG90377.1 - 0.084 12.7 0.1 1.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 Glyco_tranf_2_4 PF13704.6 GBG90377.1 - 0.16 12.5 0.0 0.54 10.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 DDE_Tnp_4 PF13359.6 GBG90378.1 - 9.6e-30 103.3 0.0 2.3e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90378.1 - 2.1e-11 43.8 0.0 3.4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90378.1 - 0.063 12.9 0.1 5.1 6.7 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain TPR_12 PF13424.6 GBG90379.1 - 9.7e-09 35.4 2.7 2.4e-06 27.7 1.3 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GBG90379.1 - 4.3e-07 29.5 0.7 0.14 12.0 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 GBG90379.1 - 0.00031 20.5 4.0 0.075 12.9 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG90379.1 - 0.00035 20.5 0.6 6.2 7.2 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 GBG90379.1 - 0.031 14.9 1.9 2 9.3 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GBG90379.1 - 0.11 12.8 0.0 5.4 7.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Hydrolase_6 PF13344.6 GBG90380.1 - 5.2e-26 90.7 0.0 9.9e-26 89.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG90380.1 - 1.3e-09 37.9 0.0 3e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GBG90380.1 - 2e-05 25.0 0.0 3.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GBG90380.1 - 0.00031 20.9 0.0 0.0075 16.4 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 GBG90380.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) HEM4 PF02602.15 GBG90380.1 - 0.081 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Macoilin PF09726.9 GBG90381.1 - 2.4 6.6 7.9 5.9 5.3 7.9 1.6 1 0 0 1 1 1 0 Macoilin family Ank_4 PF13637.6 GBG90382.1 - 2.9e-20 72.4 1.1 5e-09 36.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GBG90382.1 - 3.4e-18 66.0 0.0 6.3e-11 42.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GBG90382.1 - 6e-16 58.1 0.1 0.00029 21.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 GBG90382.1 - 9.5e-15 54.5 0.6 3.6e-08 33.5 0.2 2.9 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG90382.1 - 8.4e-13 47.3 0.0 0.032 14.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat TTL PF03133.15 GBG90383.1 - 3.5e-47 160.9 0.0 7.8e-36 123.7 0.1 2.7 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GBG90383.1 - 0.00079 18.7 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 GBG90383.1 - 0.033 13.5 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF1488 PF07369.11 GBG90384.1 - 0.28 11.2 5.2 2.4 8.2 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) RT_RNaseH_2 PF17919.1 GBG90385.1 - 1e-26 92.8 0.0 2.2e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90385.1 - 2.9e-24 85.4 0.0 6.2e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG90385.1 - 0.00015 22.0 0.1 0.00067 19.9 0.1 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG90385.1 - 0.00015 21.3 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90385.1 - 0.00018 21.5 0.1 0.00041 20.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Senescence_reg PF04520.13 GBG90385.1 - 0.028 15.3 1.5 0.054 14.3 1.0 1.7 2 0 0 2 2 2 0 Senescence regulator Ribosomal_L30_N PF08079.12 GBG90386.1 - 2.8e-25 88.4 7.5 5.6e-25 87.4 7.5 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 GBG90386.1 - 1.5e-20 72.8 2.3 1.5e-20 72.8 2.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF659 PF04937.15 GBG90388.1 - 4.3e-06 26.7 0.0 7.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF1726 PF08351.11 GBG90389.1 - 0.1 12.5 0.4 4 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) CDC45 PF02724.14 GBG90389.1 - 2.1 6.5 5.5 2.9 6.1 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Radial_spoke PF04712.12 GBG90390.1 - 0.00023 20.3 1.5 0.0003 19.9 1.5 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein TRAP_alpha PF03896.16 GBG90390.1 - 0.13 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 GBG90390.1 - 0.7 9.1 3.8 0.97 8.7 3.8 1.1 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 GBG90390.1 - 0.77 8.8 2.4 1 8.4 2.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAM176 PF14851.6 GBG90390.1 - 1.2 8.8 5.3 0.31 10.7 1.9 1.8 2 0 0 2 2 2 0 FAM176 family Trypan_PARP PF05887.11 GBG90390.1 - 1.5 8.8 13.2 3.8 7.5 13.2 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.12 GBG90390.1 - 4.8 5.3 9.0 6.4 4.9 9.0 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 GBG90390.1 - 6.7 7.2 9.7 12 6.3 9.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 GBG90391.1 - 5.2 6.3 21.7 0.022 14.1 10.0 2.1 2 0 0 2 2 2 0 NOA36 protein PAE PF03283.13 GBG90392.1 - 3.6e-32 111.9 0.0 3.5e-31 108.6 0.0 2.0 1 1 0 1 1 1 1 Pectinacetylesterase ABC_tran PF00005.27 GBG90392.1 - 9.5e-28 97.4 0.0 1.5e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GBG90392.1 - 2.4e-10 40.2 24.9 5e-10 39.1 24.9 1.5 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 GBG90392.1 - 0.0016 18.3 0.1 0.5 10.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GBG90392.1 - 0.0034 17.3 0.1 0.0065 16.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 GBG90392.1 - 0.0035 17.7 0.0 0.0077 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 GBG90392.1 - 0.0042 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 GBG90392.1 - 0.0063 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 GBG90392.1 - 0.0068 15.9 0.0 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 GBG90392.1 - 0.016 14.3 16.1 0.013 14.7 14.6 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 GBG90392.1 - 0.017 15.6 0.2 0.028 14.9 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GBG90392.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GBG90392.1 - 0.048 13.4 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 GBG90392.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GBG90392.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GBG90392.1 - 0.18 12.4 0.3 0.45 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain SDA1 PF05285.12 GBG90393.1 - 2.6 7.4 37.0 4 6.8 37.0 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG90393.1 - 8.2 5.7 40.9 9.6 5.4 40.9 1.0 1 0 0 1 1 1 0 BUD22 Pkinase_Tyr PF07714.17 GBG90395.1 - 1.6e-38 132.5 0.0 2.4e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90395.1 - 2.6e-36 125.3 0.0 4.1e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Asp_protease_2 PF13650.6 GBG90395.1 - 0.013 16.1 0.0 0.031 14.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease APH PF01636.23 GBG90395.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF659 PF04937.15 GBG90396.1 - 7.6e-19 68.1 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pkinase_Tyr PF07714.17 GBG90397.1 - 1.6e-33 116.1 0.0 4.6e-33 114.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90397.1 - 1.3e-32 113.2 0.0 1.7e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4448 PF14610.6 GBG90397.1 - 0.0075 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GRA6 PF05084.13 GBG90397.1 - 0.057 13.4 0.1 0.057 13.4 0.1 1.7 2 0 0 2 2 2 0 Granule antigen protein (GRA6) Pkinase_fungal PF17667.1 GBG90397.1 - 0.058 12.2 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GBG90397.1 - 0.096 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-bind_4 PF13837.6 GBG90399.1 - 1.9e-07 31.3 1.1 3.5e-07 30.5 1.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG90399.1 - 0.0021 18.2 2.9 0.01 16.0 2.9 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG90399.1 - 0.024 14.9 0.4 0.056 13.8 0.4 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 GBG90399.1 - 0.078 13.2 0.4 0.21 11.9 0.4 1.8 1 1 1 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG90399.1 - 0.14 12.3 1.6 0.26 11.4 1.6 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG90400.1 - 2e-06 28.1 1.4 3.7e-06 27.2 0.5 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG90400.1 - 0.00028 21.1 0.1 0.00066 19.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG90400.1 - 0.00052 20.3 0.9 0.0098 16.2 0.2 2.7 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG90400.1 - 0.0011 19.1 0.1 0.003 17.7 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG90400.1 - 0.11 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ubiquitin PF00240.23 GBG90402.1 - 7.7e-34 115.3 0.6 2.1e-33 113.9 0.4 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 GBG90402.1 - 4.1e-23 81.3 0.2 1e-22 80.0 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 GBG90402.1 - 2.8e-16 59.1 0.8 2.8e-16 59.1 0.8 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GBG90402.1 - 2.7e-05 24.6 0.2 0.00026 21.4 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GBG90402.1 - 0.00041 20.4 0.7 0.001 19.2 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GBG90402.1 - 0.0062 17.1 0.8 0.0091 16.6 0.8 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 GBG90402.1 - 0.0073 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GBG90402.1 - 0.008 16.5 0.8 0.012 15.9 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 GBG90402.1 - 0.044 13.8 1.1 9.2 6.4 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Plexin_cytopl PF08337.12 GBG90402.1 - 0.13 10.9 2.2 19 3.8 0.1 2.6 2 1 1 3 3 3 0 Plexin cytoplasmic RasGAP domain AlcCBM31 PF11606.8 GBG90402.1 - 0.13 12.4 0.2 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 Family 31 carbohydrate binding protein Myb_DNA-bind_4 PF13837.6 GBG90403.1 - 0.081 13.3 2.7 1.8 9.0 1.5 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain PTEN_C2 PF10409.9 GBG90404.1 - 4.8e-12 45.8 0.0 7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DUF4407 PF14362.6 GBG90406.1 - 0.29 10.5 21.1 5.2 6.3 7.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF2680 PF10925.8 GBG90406.1 - 2 8.5 11.2 0.11 12.5 1.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) LPP PF04728.13 GBG90406.1 - 3.3 8.2 9.5 4.1 7.9 0.0 3.8 5 0 0 5 5 5 0 Lipoprotein leucine-zipper ADIP PF11559.8 GBG90406.1 - 7.7 6.6 31.0 0.067 13.3 10.0 4.0 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DDE_Tnp_4 PF13359.6 GBG90408.1 - 8.8e-23 80.7 0.0 1.5e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90408.1 - 1.3e-09 38.0 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90408.1 - 0.063 12.9 0.3 2.1 7.9 0.1 2.6 3 0 0 3 3 3 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG90408.1 - 0.1 13.0 0.2 1.4 9.3 0.0 2.4 2 1 0 2 2 2 0 Transposase DDE domain HI0933_like PF03486.14 GBG90409.1 - 5.3e-68 229.6 0.0 5.9e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 GBG90409.1 - 0.0058 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 GBG90410.1 - 6.2e-69 232.7 0.0 6.8e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 GBG90410.1 - 0.0058 15.8 0.0 0.0099 15.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAP PF00956.18 GBG90411.1 - 7.6e-33 113.8 7.2 4.7e-28 98.1 0.5 2.5 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 GBG90411.1 - 0.022 14.7 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF1462 PF07315.11 GBG90411.1 - 0.026 14.8 0.1 0.067 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) DUF1195 PF06708.11 GBG90411.1 - 0.035 13.9 0.2 0.057 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) KaiA PF07688.12 GBG90411.1 - 0.14 12.3 0.8 0.28 11.3 0.3 1.7 2 0 0 2 2 2 0 KaiA C-terminal domain Myb_DNA-binding PF00249.31 GBG90413.1 - 1.8e-27 95.3 0.1 2.2e-14 53.3 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG90413.1 - 3.3e-21 75.3 0.1 4.5e-13 49.2 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 GBG90413.1 - 0.00044 20.3 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 2 SLIDE RVT_1 PF00078.27 GBG90415.1 - 5.1e-34 117.7 0.1 8.4e-34 117.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90415.1 - 9.6e-30 102.6 0.0 2.3e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90415.1 - 2e-28 98.7 0.0 4.7e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90415.1 - 3.3e-19 68.8 0.3 6.8e-19 67.7 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90415.1 - 1.3e-11 44.7 0.0 3.5e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG90415.1 - 6e-06 26.1 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90415.1 - 2.3e-05 24.9 0.0 5.7e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG90415.1 - 0.00019 21.6 0.1 0.00051 20.2 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG90415.1 - 0.013 16.1 0.0 0.034 14.7 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG90415.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG90415.1 - 0.2 11.5 0.0 13 5.6 0.0 2.6 2 1 0 2 2 2 0 Aspartyl protease CDC45 PF02724.14 GBG90416.1 - 0.58 8.4 21.5 0.79 7.9 21.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GBG90416.1 - 0.63 8.6 25.9 0.93 8.0 25.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 GBG90416.1 - 1.4 8.2 31.3 2.2 7.5 31.3 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG90416.1 - 1.7 8.0 32.2 2.2 7.6 32.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG90416.1 - 1.8 6.7 29.9 2.4 6.3 29.9 1.1 1 0 0 1 1 1 0 Nop14-like family CFIA_Pcf11 PF11526.8 GBG90416.1 - 2.6 8.6 8.3 70 4.0 8.3 2.7 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 PPP4R2 PF09184.11 GBG90416.1 - 6 6.4 21.7 8.2 5.9 21.7 1.3 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 GBG90416.1 - 6.6 6.4 25.9 9.7 5.8 25.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SURF2 PF05477.11 GBG90416.1 - 7.5 6.2 16.9 13 5.4 16.9 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Crp PF00325.20 GBG90417.1 - 4e-07 29.6 37.4 0.8 9.4 0.0 19.1 17 6 5 22 22 22 5 Bacterial regulatory proteins, crp family Zip PF02535.22 GBG90420.1 - 0.00063 19.1 0.1 0.0013 18.0 0.1 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter UVR PF02151.19 GBG90420.1 - 0.0038 16.9 3.9 0.0086 15.8 3.9 1.6 1 0 0 1 1 1 1 UvrB/uvrC motif CDC45 PF02724.14 GBG90420.1 - 0.9 7.8 3.2 1.3 7.3 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP_sp32 PF07222.12 GBG90420.1 - 7.6 5.9 8.5 13 5.1 8.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Glyco_transf_5 PF08323.11 GBG90421.1 - 1.5e-67 227.9 0.0 2.1e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG90421.1 - 2e-18 66.5 0.0 3.5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG90421.1 - 9.6e-14 52.0 0.0 2.5e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG90421.1 - 0.0053 16.8 0.0 5.1 7.1 0.2 2.6 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Carb_kinase PF01256.17 GBG90421.1 - 0.089 12.3 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate kinase DDE_Tnp_4 PF13359.6 GBG90422.1 - 5.9e-33 113.8 0.0 1.9e-32 112.1 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90422.1 - 9.8e-11 41.6 0.0 1.8e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90422.1 - 0.00015 21.5 0.4 0.33 10.6 0.7 2.6 2 1 0 2 2 2 2 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG90424.1 - 6.3e-32 110.4 0.0 1.2e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90424.1 - 1.7e-15 57.2 0.0 2.7e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90424.1 - 0.00068 19.3 0.4 1.3 8.6 0.0 2.8 3 1 0 3 3 3 2 Transposase DDE domain Glyco_transf_5 PF08323.11 GBG90425.1 - 1.1e-67 228.3 0.0 1.5e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG90425.1 - 0.00016 21.3 0.1 0.0003 20.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG90425.1 - 0.0024 18.3 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG90425.1 - 0.0044 17.0 0.0 4.1 7.4 0.2 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Carb_kinase PF01256.17 GBG90425.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase Glyco_transf_5 PF08323.11 GBG90426.1 - 3.9e-67 226.5 0.0 6e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG90426.1 - 9.6e-18 64.3 0.0 1.8e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG90426.1 - 1.2e-13 51.6 0.0 3.1e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG90426.1 - 0.016 15.3 0.0 5.1 7.1 0.2 2.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Carb_kinase PF01256.17 GBG90426.1 - 0.094 12.2 0.1 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate kinase Glyco_transf_5 PF08323.11 GBG90427.1 - 1.8e-48 165.4 0.0 2.8e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG90427.1 - 5.8e-19 68.3 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG90427.1 - 2e-14 54.2 0.0 4.4e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 FMN_red PF03358.15 GBG90427.1 - 0.16 11.7 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 NADPH-dependent FMN reductase DUF659 PF04937.15 GBG90428.1 - 2.9e-20 72.7 0.0 3.3e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CCSAP PF15748.5 GBG90429.1 - 0.79 9.9 22.2 0.89 9.7 22.2 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SLC12 PF03522.15 GBG90429.1 - 2.5 7.0 14.5 2.5 7.0 14.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Nop14 PF04147.12 GBG90429.1 - 4.1 5.5 53.4 4.7 5.3 53.4 1.1 1 0 0 1 1 1 0 Nop14-like family BORG_CEP PF14957.6 GBG90429.1 - 4.3 8.5 12.5 5.7 8.1 12.5 1.3 1 0 0 1 1 1 0 Cdc42 effector NPR3 PF03666.13 GBG90429.1 - 7.2 5.3 25.1 7.8 5.2 25.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CENP-N PF05238.13 GBG90429.1 - 9.7 5.4 13.2 12 5.1 13.2 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Glyco_transf_5 PF08323.11 GBG90430.1 - 1.2e-67 228.1 0.0 1.8e-67 227.6 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG90430.1 - 1.4e-18 67.0 0.0 2.5e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG90430.1 - 5.6e-14 52.7 0.0 1.2e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG90430.1 - 0.0045 17.0 0.0 4.7 7.2 0.2 2.5 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Carb_kinase PF01256.17 GBG90430.1 - 0.074 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Carbohydrate kinase FMN_red PF03358.15 GBG90430.1 - 0.098 12.4 0.0 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Myb_DNA-bind_4 PF13837.6 GBG90431.1 - 7.9e-10 39.0 1.5 1.9e-09 37.8 1.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG90431.1 - 0.0013 18.9 0.2 0.0042 17.2 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG90431.1 - 0.0047 17.2 0.8 0.012 16.0 0.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 GBG90431.1 - 0.013 16.5 0.5 0.032 15.2 0.5 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG90431.1 - 0.03 14.6 0.1 0.071 13.4 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Glyco_transf_5 PF08323.11 GBG90432.1 - 1.7e-64 217.9 0.0 2.6e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG90432.1 - 4.8e-17 62.0 0.0 8.3e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG90432.1 - 1.2e-15 58.1 0.0 3.9e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG90432.1 - 0.011 15.7 0.4 0.37 10.8 0.2 3.0 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 GBG90433.1 - 9.7e-36 123.7 0.4 4.5e-18 65.8 0.1 2.3 1 1 1 2 2 2 2 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG90433.1 - 1e-14 54.4 0.0 2.4e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG90433.1 - 4.9e-11 43.2 0.1 1.9e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Myb_DNA-bind_4 PF13837.6 GBG90433.1 - 6.1e-07 29.7 0.1 2.5e-06 27.7 0.1 2.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Astro_capsid_p PF12226.8 GBG90433.1 - 0.22 10.7 9.5 0.47 9.6 9.5 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 GBG90433.1 - 2.8 6.0 16.7 4.9 5.2 16.7 1.2 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG90434.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG90434.1 - 0.032 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Glyco_transf_5 PF08323.11 GBG90437.1 - 1.9e-64 217.7 0.0 2.7e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG90437.1 - 5e-16 58.7 0.0 8.3e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG90437.1 - 2.7e-14 53.7 0.0 1.3e-13 51.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG90437.1 - 0.0027 17.7 0.2 0.77 9.7 0.2 3.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 YL1 PF05764.13 GBG90438.1 - 3.8e-06 27.2 58.0 5e-06 26.8 58.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Nop53 PF07767.11 GBG90438.1 - 0.035 13.5 75.0 0.076 12.4 75.0 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GBG90438.1 - 0.92 7.7 58.1 1.2 7.3 58.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 GBG90438.1 - 1.1 8.0 26.3 1.2 7.9 26.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop14 PF04147.12 GBG90438.1 - 1.3 7.2 63.2 1.7 6.7 63.2 1.3 1 0 0 1 1 1 0 Nop14-like family NAM-associated PF14303.6 GBG90438.1 - 3.3 8.4 53.5 5.1 7.8 53.5 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain AF-4 PF05110.13 GBG90438.1 - 3.8 5.5 41.9 4.2 5.3 41.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2722 PF10846.8 GBG90439.1 - 0.025 13.5 4.0 0.032 13.2 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.12 GBG90439.1 - 0.091 12.2 8.1 0.12 11.8 8.1 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 GBG90439.1 - 1.3 8.3 14.1 1.8 7.8 14.1 1.1 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 GBG90439.1 - 2.3 7.3 10.7 2.7 7.0 10.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Radial_spoke PF04712.12 GBG90439.1 - 2.9 6.7 8.5 4.2 6.2 8.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Sporozoite_P67 PF05642.11 GBG90439.1 - 6.3 4.7 8.5 8.3 4.4 8.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 GBG90439.1 - 8.2 6.1 9.6 14 5.3 9.6 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 GBG90439.1 - 8.5 4.5 11.9 11 4.2 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein COPI_C PF06957.11 GBG90440.1 - 2.2e-160 533.9 0.0 2.9e-160 533.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 GBG90440.1 - 3.5e-132 441.6 0.0 5.1e-132 441.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 GBG90440.1 - 1.2e-40 136.8 15.6 3.1e-08 34.1 0.1 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG90440.1 - 3.5e-09 36.8 3.3 0.0013 19.0 0.2 5.5 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 GBG90440.1 - 0.0036 17.1 0.0 4.7 7.2 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat zinc_ribbon_9 PF14369.6 GBG90440.1 - 0.0079 16.4 0.7 0.02 15.1 0.7 1.8 1 0 0 1 1 1 1 zinc-ribbon Fis1_TPR_C PF14853.6 GBG90440.1 - 0.04 14.0 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Prok-RING_1 PF14446.6 GBG90440.1 - 0.13 12.2 0.8 0.39 10.7 0.8 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TPR_2 PF07719.17 GBG90440.1 - 0.17 12.1 0.3 16 5.9 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Nup160 PF11715.8 GBG90440.1 - 0.37 9.4 8.7 1.7 7.2 0.1 3.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Rubrerythrin PF02915.17 GBG90441.1 - 2.5e-37 128.3 0.0 4.6e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Rubrerythrin FA_desaturase_2 PF03405.14 GBG90441.1 - 0.035 12.9 0.0 4.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Fatty acid desaturase RVT_1 PF00078.27 GBG90443.1 - 2.4e-16 59.9 0.0 5.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90443.1 - 3.2e-13 49.5 0.0 6.7e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90443.1 - 5.5e-07 29.8 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90443.1 - 0.0095 16.1 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain PWI PF01480.17 GBG90444.1 - 3.6e-28 97.7 0.5 6.4e-28 96.9 0.5 1.4 1 0 0 1 1 1 1 PWI domain PWI PF01480.17 GBG90445.1 - 3.5e-28 97.7 0.5 6.3e-28 96.9 0.5 1.4 1 0 0 1 1 1 1 PWI domain zf-CCHC PF00098.23 GBG90447.1 - 0.0095 16.0 0.9 0.016 15.3 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle HEXIM PF15313.6 GBG90448.1 - 0.053 13.7 0.9 0.084 13.1 0.9 1.2 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein RVT_1 PF00078.27 GBG90450.1 - 2.8e-22 79.3 0.0 4.4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L38e PF01781.18 GBG90451.1 - 1.4e-34 118.0 2.0 1.5e-34 117.9 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF659 PF04937.15 GBG90452.1 - 5.5e-31 107.5 0.2 1.1e-30 106.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90452.1 - 0.095 12.5 0.1 1 9.2 0.0 2.6 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Retrotrans_gag PF03732.17 GBG90453.1 - 0.018 15.3 1.9 0.041 14.2 0.1 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein ArsR PF09824.9 GBG90453.1 - 0.31 10.6 2.9 16 5.1 0.1 2.9 3 0 0 3 3 3 0 ArsR transcriptional regulator Exo_endo_phos PF03372.23 GBG90454.1 - 5e-12 45.8 0.0 1e-05 25.2 0.0 3.5 3 1 0 3 3 3 2 Endonuclease/Exonuclease/phosphatase family BUD22 PF09073.10 GBG90454.1 - 0.00074 19.0 25.8 0.00074 19.0 25.8 1.8 2 0 0 2 2 2 1 BUD22 CDC45 PF02724.14 GBG90454.1 - 0.037 12.3 17.8 0.075 11.3 17.2 1.7 2 0 0 2 2 2 0 CDC45-like protein PapD-like PF14874.6 GBG90454.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like T_cell_tran_alt PF15128.6 GBG90454.1 - 0.15 11.9 1.3 2.4 8.0 0.2 2.7 2 0 0 2 2 2 0 T-cell leukemia translocation-altered SAPS PF04499.15 GBG90454.1 - 0.41 9.4 5.1 0.73 8.5 5.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Eapp_C PF10238.9 GBG90454.1 - 0.68 10.0 6.5 0.036 14.2 0.4 2.1 2 0 0 2 2 1 0 E2F-associated phosphoprotein NPR3 PF03666.13 GBG90454.1 - 0.75 8.5 7.2 1.3 7.7 7.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 GBG90454.1 - 2.2 8.0 5.3 4.4 7.0 5.3 1.4 1 0 0 1 1 1 0 AAA domain DUF2052 PF09747.9 GBG90454.1 - 2.7 8.1 26.4 11 6.1 26.4 2.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 GBG90454.1 - 5 7.2 4.8 1.7 8.7 1.0 2.0 2 0 0 2 2 2 0 DDHD domain DUF5523 PF17661.1 GBG90454.1 - 5 6.7 23.8 13 5.4 23.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF913 PF06025.12 GBG90454.1 - 5.3 5.9 6.1 12 4.8 6.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) KxDL PF10241.9 GBG90455.1 - 0.23 11.7 3.3 0.74 10.1 0.4 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein PIF1 PF05970.14 GBG90456.1 - 2.1e-63 214.7 0.0 3.8e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase ATG7_N PF16420.5 GBG90457.1 - 1.6e-79 267.7 0.0 2.4e-78 263.8 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 GBG90457.1 - 3.7e-43 147.6 0.0 1.3e-42 145.9 0.0 1.7 1 1 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 GBG90457.1 - 0.015 15.3 0.2 0.04 14.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F-box-like PF12937.7 GBG90457.1 - 0.028 14.3 0.0 2.4 8.1 0.1 2.6 2 0 0 2 2 2 0 F-box-like Asp_protease_2 PF13650.6 GBG90459.1 - 7e-05 23.4 0.0 0.00045 20.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90459.1 - 0.00018 22.0 0.0 0.00054 20.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG90459.1 - 0.0013 18.8 2.9 0.0029 17.6 2.9 1.6 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG90460.1 - 6e-29 101.1 0.1 9.9e-29 100.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG90460.1 - 2.3e-12 46.6 0.0 5.6e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG90460.1 - 0.0023 18.1 0.0 0.0074 16.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG90460.1 - 0.13 12.9 0.0 0.34 11.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease IFT57 PF10498.9 GBG90461.1 - 0.6 9.0 3.0 0.91 8.4 3.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RVP_2 PF08284.11 GBG90462.1 - 3.3e-07 30.1 0.0 9.9e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90462.1 - 1.2e-05 25.9 0.0 2.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90462.1 - 0.00019 21.9 0.0 0.00073 20.0 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG90462.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG90462.1 - 0.029 14.2 0.0 0.06 13.1 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease REV PF00424.18 GBG90462.1 - 0.32 11.1 0.1 0.32 11.1 0.1 2.9 3 1 0 3 3 3 0 REV protein (anti-repression trans-activator protein) Mrr_N PF14338.6 GBG90462.1 - 4.2 7.6 9.3 1.5 9.0 2.7 3.1 3 0 0 3 3 3 0 Mrr N-terminal domain Es2 PF09751.9 GBG90463.1 - 0.0032 17.3 13.4 0.0058 16.4 13.4 1.3 1 1 0 1 1 1 1 Nuclear protein Es2 TadF PF16964.5 GBG90463.1 - 0.12 12.1 1.9 0.16 11.7 1.9 1.1 1 0 0 1 1 1 0 Putative tight adherence pilin protein F V_ATPase_I PF01496.19 GBG90463.1 - 7.9 4.3 9.1 8.6 4.1 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Clp_N PF02861.20 GBG90464.1 - 9e-18 64.1 0.1 1.9e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 Clp amino terminal domain, pathogenicity island component SIMPL PF04402.14 GBG90464.1 - 1.3 9.4 7.7 5.3 7.4 7.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF541) TIM PF00121.18 GBG90465.1 - 3.1e-11 43.1 0.0 1.7e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Triosephosphate isomerase HSP70 PF00012.20 GBG90467.1 - 4.8e-81 272.7 0.0 6.2e-58 196.4 0.0 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG90467.1 - 1e-10 41.0 0.0 1.8e-07 30.3 0.1 3.3 3 1 0 3 3 3 2 MreB/Mbl protein TIM PF00121.18 GBG90467.1 - 2.1e-09 37.1 0.0 3.6e-07 29.8 0.0 2.8 2 0 0 2 2 2 2 Triosephosphate isomerase Myb_DNA-bind_4 PF13837.6 GBG90468.1 - 1.2e-09 38.4 6.6 6.4e-08 32.9 4.4 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG90468.1 - 0.044 14.1 4.5 0.036 14.4 2.6 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AChE_tetra PF08674.10 GBG90468.1 - 0.15 11.8 2.2 0.32 10.7 2.2 1.5 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Rrn6 PF10214.9 GBG90469.1 - 0.07 11.6 1.3 0.1 11.1 1.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DDE_Tnp_4 PF13359.6 GBG90470.1 - 8.7e-24 84.0 0.0 1.2e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90470.1 - 2.6e-12 46.8 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90470.1 - 0.002 17.8 0.2 0.0072 16.0 0.0 1.9 2 0 0 2 2 2 1 Transposase DDE domain HSP70 PF00012.20 GBG90471.1 - 2.2e-80 270.6 0.0 9.9e-57 192.4 0.1 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG90471.1 - 3.6e-11 42.5 0.1 7.1e-08 31.6 0.3 2.7 2 1 0 2 2 2 2 MreB/Mbl protein TIM PF00121.18 GBG90471.1 - 0.00085 18.8 0.0 0.088 12.2 0.0 2.7 2 0 0 2 2 2 2 Triosephosphate isomerase RVT_1 PF00078.27 GBG90473.1 - 1.5e-59 201.2 0.6 9.7e-29 100.5 0.0 3.0 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) HSP70 PF00012.20 GBG90473.1 - 7e-55 186.3 0.0 4.4e-53 180.4 0.0 2.5 1 1 0 1 1 1 1 Hsp70 protein TIM PF00121.18 GBG90473.1 - 9e-41 139.8 0.0 2.1e-13 50.2 0.0 6.4 6 0 0 6 6 6 5 Triosephosphate isomerase RT_RNaseH_2 PF17919.1 GBG90473.1 - 2.1e-14 53.4 0.2 1e-13 51.1 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase MreB_Mbl PF06723.13 GBG90473.1 - 5.3e-06 25.5 1.2 0.096 11.5 0.0 2.8 2 1 0 2 2 2 2 MreB/Mbl protein RT_RNaseH PF17917.1 GBG90473.1 - 0.00013 22.2 0.0 0.0012 19.1 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RNA_pol_3_Rpc31 PF11705.8 GBG90474.1 - 0.042 14.1 5.5 0.062 13.5 5.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.19 GBG90474.1 - 0.2 12.3 15.4 0.36 11.4 15.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein HSP70 PF00012.20 GBG90475.1 - 5e-88 295.8 0.0 1.6e-62 211.6 0.0 2.3 1 1 1 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG90475.1 - 8.6e-25 87.5 0.0 0.0002 20.8 0.0 6.4 5 1 1 6 6 6 6 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG90475.1 - 3.9e-08 32.5 0.2 0.029 13.2 0.0 4.1 4 0 0 4 4 4 3 MreB/Mbl protein Fer4_12 PF13353.6 GBG90475.1 - 0.12 12.7 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain HSP70 PF00012.20 GBG90476.1 - 1.7e-88 297.3 0.0 4e-62 210.3 0.0 2.4 1 1 1 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG90476.1 - 3e-26 92.3 0.0 2.9e-10 39.9 0.0 5.7 5 1 0 5 5 5 5 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG90476.1 - 7.1e-10 38.2 0.1 2.2e-07 30.0 0.0 3.9 3 1 0 3 3 3 1 MreB/Mbl protein DUF4226 PF10774.9 GBG90476.1 - 0.37 11.1 3.0 1.3 9.4 3.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) DUF4600 PF15372.6 GBG90476.1 - 5.9 7.3 6.3 33 4.9 1.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) DDE_Tnp_4 PF13359.6 GBG90477.1 - 4e-27 94.8 0.0 1.4e-26 93.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90477.1 - 6.3e-13 48.8 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90477.1 - 2.5e-05 24.0 0.4 0.014 15.1 0.0 3.1 3 0 0 3 3 3 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG90477.1 - 0.0091 16.4 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Transposase DDE domain Sec16_N PF12935.7 GBG90478.1 - 0.0083 16.3 1.7 0.017 15.3 1.7 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 N-terminus MAP17 PF15807.5 GBG90478.1 - 0.043 14.0 0.9 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RT_RNaseH_2 PF17919.1 GBG90479.1 - 3.2e-26 91.3 0.0 7.5e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90479.1 - 3.1e-24 85.3 0.0 6.5e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90479.1 - 9.4e-21 73.7 0.3 4.7e-20 71.5 0.3 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG90479.1 - 8.8e-12 45.0 0.1 1.6e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90479.1 - 7.2e-10 39.1 0.0 2.2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG90479.1 - 0.0022 17.9 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG90479.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger HSP70 PF00012.20 GBG90480.1 - 1.1e-103 347.5 2.2 6.4e-82 275.6 0.1 2.2 2 0 0 2 2 2 2 Hsp70 protein zf-CCHC PF00098.23 GBG90480.1 - 2.4e-09 36.8 9.1 0.00026 20.9 1.9 2.6 2 0 0 2 2 2 2 Zinc knuckle MreB_Mbl PF06723.13 GBG90480.1 - 1.5e-07 30.5 0.9 7.6e-05 21.7 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG90480.1 - 0.0028 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain CbiJ PF02571.14 GBG90480.1 - 0.037 13.5 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK zf-CCHC_6 PF15288.6 GBG90480.1 - 0.91 9.4 5.4 6.5 6.7 0.2 2.6 1 1 1 2 2 2 0 Zinc knuckle LRR_11 PF18831.1 GBG90480.1 - 4.5 6.9 5.1 20 4.9 0.5 2.4 2 0 0 2 2 2 0 Leucine-rich repeat Integrase_H2C2 PF17921.1 GBG90481.1 - 6.5e-15 55.0 0.4 2.2e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90481.1 - 1e-13 51.5 0.0 2.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90481.1 - 1.7e-10 40.9 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90481.1 - 2.1e-06 27.4 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 GBG90481.1 - 0.69 8.1 8.1 1.2 7.3 8.1 1.3 1 0 0 1 1 1 0 CDC45-like protein HSP70 PF00012.20 GBG90482.1 - 1e-110 370.8 0.0 1.6e-110 370.1 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG90482.1 - 2.4e-06 26.6 0.0 0.00023 20.1 0.0 2.8 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GBG90482.1 - 0.029 14.1 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Ank_4 PF13637.6 GBG90485.1 - 2.1e-38 130.2 3.3 4.5e-12 46.2 0.0 5.2 3 2 3 6 6 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 GBG90485.1 - 3.7e-36 123.6 0.3 9.6e-13 48.5 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GBG90485.1 - 5.8e-29 96.9 4.2 4.9e-05 23.4 0.0 7.8 8 0 0 8 8 7 6 Ankyrin repeat Ank_5 PF13857.6 GBG90485.1 - 6.5e-25 86.9 6.2 7.8e-08 32.4 0.0 6.8 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 GBG90485.1 - 2.4e-21 75.2 6.7 0.00038 20.8 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat TPR_2 PF07719.17 GBG90485.1 - 7.4e-08 31.9 5.4 0.0011 18.9 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG90485.1 - 1.8e-06 27.5 2.8 0.0025 17.5 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG90485.1 - 0.00021 21.3 1.0 0.045 14.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat CS PF04969.16 GBG90485.1 - 0.0027 18.7 0.0 0.0053 17.7 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_16 PF13432.6 GBG90485.1 - 0.0028 18.3 8.7 0.018 15.7 4.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG90485.1 - 0.017 14.8 0.4 0.55 10.0 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 GBG90485.1 - 0.2 12.5 0.1 0.2 12.5 0.1 4.1 4 1 1 5 5 2 0 Tetratricopeptide repeat DUF1707 PF08044.11 GBG90485.1 - 1.9 8.6 6.1 2.6 8.2 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1707) UQ_con PF00179.26 GBG90487.1 - 2.6e-49 166.5 0.0 2.9e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GBG90487.1 - 5.6e-05 22.9 0.0 6.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B HTH_29 PF13551.6 GBG90487.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix RWD PF05773.22 GBG90487.1 - 0.067 13.5 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain PCRF PF03462.18 GBG90488.1 - 1.4e-60 204.5 0.5 3.1e-60 203.4 0.5 1.6 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 GBG90488.1 - 1.5e-39 134.5 3.7 1.5e-39 134.5 3.7 2.0 2 0 0 2 2 2 1 RF-1 domain SURF1 PF02104.15 GBG90488.1 - 1.8e-35 122.7 0.0 8e-33 114.1 0.0 2.6 1 1 0 1 1 1 1 SURF1 family RVT_1 PF00078.27 GBG90490.1 - 8.6e-26 90.8 0.1 1.5e-25 90.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90490.1 - 1.2e-24 86.2 0.0 3.9e-24 84.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90490.1 - 9e-23 80.6 0.0 3e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG90490.1 - 1.8e-05 24.5 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG90490.1 - 2.5e-05 24.8 0.0 4.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90490.1 - 4e-05 24.2 0.0 8.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG90490.1 - 0.0032 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90491.1 - 8.3e-05 23.1 0.0 0.00019 21.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90491.1 - 0.0001 22.9 0.0 0.00022 21.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG90491.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease APG6_N PF17675.1 GBG90492.1 - 0.0075 16.8 16.1 0.0075 16.8 16.1 2.5 1 1 1 2 2 2 1 Apg6 coiled-coil region TolA_bind_tri PF16331.5 GBG90492.1 - 0.01 15.9 11.1 0.44 10.7 1.1 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation ATG16 PF08614.11 GBG90492.1 - 0.15 12.2 21.5 0.052 13.8 17.8 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 GBG90492.1 - 0.23 11.8 11.2 0.87 9.9 6.2 3.2 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAUS-augmin3 PF14932.6 GBG90492.1 - 0.36 10.4 18.6 0.45 10.0 18.0 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 LRS4 PF10422.9 GBG90492.1 - 0.42 10.1 13.6 0.63 9.6 13.6 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TPR_MLP1_2 PF07926.12 GBG90492.1 - 0.43 10.7 27.2 0.14 12.2 15.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 GBG90492.1 - 0.47 10.5 32.9 0.64 10.0 32.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Allexi_40kDa PF05549.11 GBG90492.1 - 0.48 9.9 4.3 0.52 9.8 3.2 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein Snapin_Pallidin PF14712.6 GBG90492.1 - 0.53 10.7 15.1 0.1 13.1 8.2 2.8 1 1 2 3 3 3 0 Snapin/Pallidin HALZ PF02183.18 GBG90492.1 - 0.57 10.5 11.3 0.6 10.4 1.8 3.9 3 1 0 4 4 4 0 Homeobox associated leucine zipper Fez1 PF06818.15 GBG90492.1 - 0.6 10.5 27.3 0.41 11.1 23.4 1.9 1 1 1 2 2 2 0 Fez1 FlxA PF14282.6 GBG90492.1 - 0.7 9.9 16.0 0.79 9.7 14.3 1.8 1 1 0 1 1 1 0 FlxA-like protein DUF2730 PF10805.8 GBG90492.1 - 0.87 9.7 15.2 0.22 11.6 2.7 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 GBG90492.1 - 1.7 9.1 20.2 0.17 12.3 3.8 3.5 3 2 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF737 PF05300.11 GBG90492.1 - 1.8 8.9 22.6 2.3 8.5 22.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) YabA PF06156.13 GBG90492.1 - 1.8 9.2 19.6 0.44 11.2 9.5 3.2 1 1 3 4 4 4 0 Initiation control protein YabA ADIP PF11559.8 GBG90492.1 - 1.9 8.6 20.1 1 9.4 8.1 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 GBG90492.1 - 1.9 6.3 11.8 2.7 5.8 11.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AATF-Che1 PF13339.6 GBG90492.1 - 2.2 9.0 14.6 5.6 7.6 14.3 1.8 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor bZIP_1 PF00170.21 GBG90492.1 - 3.2 7.9 33.4 0.23 11.6 8.8 3.8 3 1 1 4 4 3 0 bZIP transcription factor ExsD PF16806.5 GBG90492.1 - 3.8 7.4 9.2 3.3 7.6 8.0 1.4 1 1 0 1 1 1 0 Antiactivator protein ExsD DUF1664 PF07889.12 GBG90492.1 - 4 7.5 14.2 0.7 9.9 5.7 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) GBP_C PF02841.14 GBG90492.1 - 4.1 6.7 27.7 0.39 10.1 17.4 2.1 1 1 1 2 2 2 0 Guanylate-binding protein, C-terminal domain AAA_13 PF13166.6 GBG90492.1 - 4.5 5.8 19.6 8.8 4.8 19.7 1.3 1 1 0 1 1 1 0 AAA domain Jnk-SapK_ap_N PF09744.9 GBG90492.1 - 5 7.3 29.0 1.6 9.0 25.2 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Sipho_Gp157 PF05565.11 GBG90492.1 - 5.3 7.0 24.8 0.97 9.4 5.8 2.5 1 1 1 2 2 2 0 Siphovirus Gp157 Macoilin PF09726.9 GBG90492.1 - 5.7 5.4 17.4 6.2 5.3 17.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4776 PF16003.5 GBG90492.1 - 6.2 5.7 14.6 6 5.7 14.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4776) Hid1 PF12722.7 GBG90492.1 - 6.9 4.7 9.3 8.1 4.4 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Fib_alpha PF08702.10 GBG90492.1 - 6.9 6.9 12.7 5.9 7.1 10.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 GBG90492.1 - 7.5 5.7 19.0 2.7 7.1 15.5 1.8 1 1 1 2 2 2 0 TMPIT-like protein DUF2855 PF11017.8 GBG90492.1 - 8.3 6.1 6.2 11 5.6 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) zf-TAZ PF02135.16 GBG90493.1 - 4.3e-12 46.3 13.1 4.3e-12 46.3 13.1 2.8 4 0 0 4 4 4 1 TAZ zinc finger DUF308 PF03729.13 GBG90494.1 - 0.00035 20.8 41.6 0.016 15.5 19.0 3.3 2 1 1 3 3 3 3 Short repeat of unknown function (DUF308) F1F0-ATPsyn_F PF10791.9 GBG90495.1 - 0.00021 21.7 0.1 0.00026 21.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi D123 PF07065.14 GBG90497.1 - 8.6e-77 258.3 0.0 1.3e-76 257.7 0.0 1.3 1 1 0 1 1 1 1 D123 R2K_2 PF18299.1 GBG90497.1 - 0.0054 16.6 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 GBG90497.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Macoilin PF09726.9 GBG90498.1 - 5.4 5.4 10.3 7.3 5.0 10.3 1.2 1 0 0 1 1 1 0 Macoilin family Mobilization_B PF17511.2 GBG90499.1 - 0.0078 16.6 0.7 0.015 15.6 0.7 1.4 1 0 0 1 1 1 1 Mobilization protein B DUF2207 PF09972.9 GBG90499.1 - 0.05 12.4 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Biotin_lipoyl PF00364.22 GBG90500.1 - 2.4e-24 84.9 0.2 3.9e-24 84.3 0.2 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GBG90500.1 - 4.6e-07 29.6 1.1 0.016 15.0 0.1 2.5 2 1 1 3 3 3 2 Biotin-lipoyl like DUF2028 PF09667.10 GBG90500.1 - 0.033 14.2 0.3 0.052 13.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2028) RnfC_N PF13375.6 GBG90500.1 - 0.033 14.1 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 GBG90500.1 - 0.12 12.2 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 GBG90500.1 - 0.22 10.7 0.0 12 5.1 0.0 2.1 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion YqfD PF06898.11 GBG90500.1 - 0.46 9.3 1.8 6.2 5.6 0.1 2.1 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD PRMT5_TIM PF17285.2 GBG90501.1 - 5e-75 252.0 0.0 6.8e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 GBG90501.1 - 1.7e-71 239.6 0.0 2.5e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 GBG90501.1 - 3.2e-52 177.0 1.0 5.8e-52 176.1 1.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 GBG90501.1 - 0.0025 17.6 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5_TIM PF17285.2 GBG90502.1 - 2.5e-75 253.0 0.0 3.4e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 GBG90502.1 - 1.7e-71 239.6 0.0 2.5e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 GBG90502.1 - 3.2e-52 177.0 1.0 5.8e-52 176.1 1.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 GBG90502.1 - 0.0025 17.6 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5_TIM PF17285.2 GBG90503.1 - 1.6e-75 253.6 0.0 2.2e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 GBG90503.1 - 1.7e-71 239.6 0.0 2.5e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 GBG90503.1 - 3.2e-52 177.0 1.0 5.8e-52 176.1 1.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 GBG90503.1 - 0.0025 17.6 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein IFT46_B_C PF12317.8 GBG90504.1 - 1.2e-44 152.6 0.2 1.4e-44 152.4 0.2 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Thymidylate_kin PF02223.17 GBG90506.1 - 1.1e-43 149.1 0.9 1.9e-43 148.3 0.0 1.8 2 0 0 2 2 2 1 Thymidylate kinase WDCP PF15390.6 GBG90506.1 - 0.3 9.4 1.2 0.42 8.9 1.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DARPP-32 PF05395.12 GBG90506.1 - 3.7 7.8 12.6 6.1 7.0 12.6 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 AP1AR PF15745.5 GBG90507.1 - 0.00091 18.9 14.0 0.0017 18.0 14.0 1.4 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein Peptidase_M90 PF06167.12 GBG90507.1 - 0.042 13.4 0.3 0.042 13.4 0.3 1.6 2 0 0 2 2 2 0 Glucose-regulated metallo-peptidase M90 HAUS-augmin3 PF14932.6 GBG90507.1 - 0.18 11.3 12.4 0.29 10.7 12.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Proteasome PF00227.26 GBG90508.1 - 9.5e-33 113.3 2.0 6.6e-29 100.8 0.5 2.1 1 1 1 2 2 2 2 Proteasome subunit Pr_beta_C PF12465.8 GBG90508.1 - 0.0061 15.9 0.3 0.0061 15.9 0.3 2.1 2 0 0 2 2 2 1 Proteasome beta subunits C terminal PDEase_I_N PF08499.12 GBG90508.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Proteasome PF00227.26 GBG90509.1 - 3.3e-41 140.9 0.8 4.5e-41 140.4 0.8 1.1 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.29 GBG90510.1 - 5.3e-48 163.1 0.0 8.8e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG90510.1 - 2.7e-29 101.8 0.0 9.2e-29 100.0 0.0 1.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG90510.1 - 4.5e-05 23.5 0.0 7.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GBG90510.1 - 0.15 11.8 0.0 1.1 9.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GBG90510.1 - 0.2 11.9 0.1 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Histone PF00125.24 GBG90511.1 - 5.9e-26 91.4 0.1 5.9e-26 91.4 0.1 3.3 3 2 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GBG90511.1 - 0.0032 17.7 1.6 0.017 15.4 0.0 3.0 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RT_RNaseH PF17917.1 GBG90512.1 - 4.4e-22 78.3 0.0 9.2e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90512.1 - 2.6e-20 72.3 0.0 5.6e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG90512.1 - 3e-07 30.9 0.0 1e-06 29.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG90512.1 - 2.7e-06 27.1 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG90512.1 - 0.00016 22.3 0.0 0.00042 20.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG90512.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 GBG90513.1 - 5.3e-14 52.4 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG90513.1 - 7.4e-14 51.6 0.0 1.6e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG90513.1 - 8.7e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90513.1 - 0.00021 20.9 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG90513.1 - 0.00032 21.2 0.0 0.00073 20.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90513.1 - 0.003 18.2 0.0 0.0066 17.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 GBG90513.1 - 0.0076 16.5 0.0 0.049 13.9 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG90513.1 - 0.011 16.0 0.1 0.058 13.7 0.0 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG90513.1 - 0.013 15.3 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.6 GBG90513.1 - 0.02 14.7 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RVP PF00077.20 GBG90513.1 - 0.029 14.7 0.1 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease rve PF00665.26 GBG90514.1 - 1.3e-14 54.4 0.0 2.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG90514.1 - 5.9e-14 51.9 0.0 1.5e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GBG90514.1 - 0.0098 15.7 0.0 0.035 13.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG90514.1 - 0.017 15.4 0.3 0.054 13.8 0.3 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein DUF659 PF04937.15 GBG90515.1 - 2.1e-24 86.1 1.5 2.4e-24 86.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90515.1 - 0.0036 17.0 0.1 0.0088 15.8 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 GBG90515.1 - 0.096 12.7 0.7 0.22 11.6 0.7 1.6 1 0 0 1 1 1 0 BED zinc finger RT_RNaseH_2 PF17919.1 GBG90516.1 - 6.1e-31 106.4 0.0 1.8e-30 104.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90516.1 - 6.6e-31 106.7 0.2 2.1e-30 105.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90516.1 - 3.6e-18 65.4 0.5 3.6e-18 65.4 0.5 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG90516.1 - 6.2e-15 55.3 0.1 1.3e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90516.1 - 8.3e-06 26.0 0.0 1.9e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90516.1 - 0.00059 20.0 0.1 0.0023 18.1 0.1 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG90516.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.5 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 GBG90517.1 - 2.8e-28 98.9 0.0 4.3e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) U-box PF04564.15 GBG90517.1 - 2.7e-20 72.3 0.1 6.6e-20 71.1 0.1 1.7 1 0 0 1 1 1 1 U-box domain RVP_2 PF08284.11 GBG90517.1 - 0.0022 17.8 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-Nse PF11789.8 GBG90517.1 - 0.0036 17.1 0.1 0.0073 16.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 GBG90517.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 GBG90517.1 - 0.039 14.1 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein HAGH_C PF16123.5 GBG90518.1 - 0.21 12.1 1.4 0.41 11.2 0.6 1.9 2 0 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus MSP1_C PF07462.11 GBG90518.1 - 0.35 9.5 4.3 0.064 11.9 0.8 1.6 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_60s PF00428.19 GBG90520.1 - 4e-06 27.3 0.0 4e-06 27.3 0.0 9.0 1 1 4 5 5 5 1 60s Acidic ribosomal protein RVT_1 PF00078.27 GBG90521.1 - 6.9e-29 100.9 0.4 1.3e-28 100.1 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90521.1 - 2.3e-18 66.1 0.1 4.6e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90521.1 - 3.3e-15 56.2 0.2 1.5e-09 38.0 0.2 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90521.1 - 1.3e-14 54.0 0.0 4.2e-10 39.5 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90521.1 - 2.1e-09 37.6 0.1 7.7e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG90521.1 - 0.0016 18.3 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RVP_2 PF08284.11 GBG90521.1 - 0.0044 16.8 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.24 GBG90521.1 - 0.033 14.1 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ERM PF00769.19 GBG90522.1 - 0.018 14.9 11.6 0.026 14.4 11.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2514 PF10721.9 GBG90522.1 - 0.25 11.3 2.1 0.54 10.3 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RT_RNaseH PF17917.1 GBG90523.1 - 6.1e-29 100.4 0.1 1.3e-27 96.1 0.0 2.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90523.1 - 2.2e-28 98.2 0.0 1.8e-27 95.3 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90523.1 - 7.5e-19 67.6 0.8 2e-18 66.2 0.8 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90523.1 - 3.7e-17 62.6 0.1 2.1e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG90523.1 - 0.0016 18.6 0.3 0.0045 17.2 0.3 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF659 PF04937.15 GBG90524.1 - 1.5e-06 28.1 0.2 7.7e-06 25.8 0.0 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90524.1 - 0.0014 18.3 0.1 0.0036 17.0 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF966 PF06136.13 GBG90524.1 - 5.4 6.6 13.4 8.5 6.0 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Dynein_C PF18199.1 GBG90525.1 - 2.5e-33 115.6 0.2 5.5e-33 114.5 0.0 1.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain rve PF00665.26 GBG90525.1 - 2.3e-11 43.9 0.2 3.9e-11 43.2 0.2 1.3 1 0 0 1 1 1 1 Integrase core domain Cas_Cas2CT1978 PF09707.10 GBG90525.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Pectinesterase PF01095.19 GBG90526.1 - 2.7e-63 213.5 0.1 3.4e-63 213.1 0.1 1.0 1 0 0 1 1 1 1 Pectinesterase Pectinesterase PF01095.19 GBG90527.1 - 1.5e-75 253.7 0.3 1.9e-75 253.4 0.3 1.1 1 0 0 1 1 1 1 Pectinesterase DUF563 PF04577.14 GBG90528.1 - 7.8e-18 65.4 0.0 1.2e-17 64.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) LisH PF08513.11 GBG90528.1 - 0.032 14.2 0.1 0.078 13.0 0.1 1.6 1 0 0 1 1 1 0 LisH CofC PF01983.16 GBG90528.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Guanylyl transferase CofC like RVT_1 PF00078.27 GBG90529.1 - 5.9e-31 107.7 0.1 8.5e-31 107.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bestrophin PF01062.21 GBG90530.1 - 5.2e-23 81.9 6.7 7.3e-23 81.4 6.7 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel gag-asp_proteas PF13975.6 GBG90531.1 - 3.2e-05 24.4 0.1 6.9e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG90531.1 - 3.8e-05 23.3 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG90531.1 - 0.0041 17.7 0.1 0.0095 16.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG90531.1 - 0.035 13.8 0.3 0.12 12.1 0.3 1.9 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RVP_2 PF08284.11 GBG90531.1 - 0.045 13.5 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG90531.1 - 0.099 12.8 1.9 0.19 11.8 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 GBG90531.1 - 0.2 11.5 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease CPP1-like PF11833.8 GBG90533.1 - 3.7e-36 124.6 0.9 5e-36 124.2 0.9 1.1 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DnaJ PF00226.31 GBG90533.1 - 0.025 14.7 0.4 0.041 14.0 0.4 1.4 1 0 0 1 1 1 0 DnaJ domain Osmo_CC PF08946.10 GBG90533.1 - 0.075 13.3 2.3 0.13 12.5 2.3 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil gag-asp_proteas PF13975.6 GBG90536.1 - 1.4e-06 28.8 0.0 2.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90536.1 - 7.1e-05 23.4 0.0 0.00024 21.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG90536.1 - 0.00048 19.9 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG90536.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG90536.1 - 0.39 10.9 1.9 0.77 10.0 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4381 PF14316.6 GBG90537.1 - 0.071 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PepSY_TM PF03929.16 GBG90537.1 - 0.23 11.1 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Serglycin PF04360.12 GBG90539.1 - 3.3 7.7 6.2 6.8 6.6 1.6 3.1 2 0 0 2 2 2 0 Serglycin DDE_Tnp_4 PF13359.6 GBG90541.1 - 2.1e-30 105.5 0.0 5e-30 104.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90541.1 - 1.4e-15 57.5 0.0 2.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90541.1 - 0.00044 20.0 0.3 0.44 10.2 0.0 3.0 3 0 0 3 3 3 2 Transposase DDE domain Retrotrans_gag PF03732.17 GBG90543.1 - 0.099 12.9 1.5 0.35 11.2 0.1 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein RasGEF_N PF00618.20 GBG90543.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 RasGEF N-terminal motif Cob_adeno_trans PF01923.18 GBG90543.1 - 3.3 7.8 6.9 8.7 6.5 2.7 2.8 2 1 1 3 3 3 0 Cobalamin adenosyltransferase DUF1690 PF07956.11 GBG90543.1 - 5.9 7.3 9.5 2.2 8.7 5.7 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Arginase PF00491.21 GBG90544.1 - 5.2e-69 232.9 0.0 6.6e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 GBG90544.1 - 0.012 15.9 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Nop14 PF04147.12 GBG90545.1 - 0.59 8.3 6.0 0.58 8.3 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG90545.1 - 0.86 7.8 7.2 1 7.5 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein KH_1 PF00013.29 GBG90546.1 - 2.4e-36 123.3 7.6 2.4e-13 49.7 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GBG90546.1 - 4.6e-08 32.8 1.9 0.0096 15.7 0.1 3.2 3 0 0 3 3 3 2 KH domain KH_4 PF13083.6 GBG90546.1 - 0.00016 21.5 0.9 0.053 13.4 0.1 2.5 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 GBG90546.1 - 0.0052 16.8 0.5 2.8 8.1 0.1 2.9 3 0 0 3 3 3 2 NusA-like KH domain ANAPC4 PF12896.7 GBG90547.1 - 4.1e-36 124.4 2.5 4.3e-36 124.3 0.7 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 GBG90547.1 - 6.5e-27 93.7 0.4 1.3e-26 92.7 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain GDPD PF03009.17 GBG90547.1 - 1.8e-06 27.9 0.0 0.0055 16.5 0.0 3.4 4 1 0 4 4 4 2 Glycerophosphoryl diester phosphodiesterase family WD40 PF00400.32 GBG90547.1 - 0.00041 21.1 2.5 0.0047 17.7 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Retrotrans_gag PF03732.17 GBG90547.1 - 0.0033 17.7 0.1 0.3 11.4 0.0 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein Coatomer_WDAD PF04053.14 GBG90547.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Senescence_reg PF04520.13 GBG90547.1 - 0.16 12.8 2.3 0.61 10.9 2.3 1.9 1 0 0 1 1 1 0 Senescence regulator COX6A PF02046.15 GBG90548.1 - 6.1e-07 29.9 0.1 8.1e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa rve PF00665.26 GBG90550.1 - 0.036 14.2 0.1 0.094 12.9 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 GBG90550.1 - 0.047 14.0 0.2 0.12 12.7 0.2 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG90551.1 - 1.9e-23 83.2 0.4 1.4e-22 80.4 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG90551.1 - 5e-21 74.9 0.0 1.4e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90551.1 - 2.4e-20 72.4 0.0 6.6e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG90551.1 - 0.0048 17.2 0.2 0.099 12.9 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG90551.1 - 0.054 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90552.1 - 6.1e-25 87.5 0.0 1.3e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90552.1 - 2.8e-24 85.9 0.4 7.2e-24 84.5 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90552.1 - 3.8e-24 84.6 0.0 7.8e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90552.1 - 1.3e-18 66.8 0.6 2.9e-18 65.7 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90552.1 - 6.9e-10 39.2 0.0 4.4e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG90552.1 - 0.0013 19.0 1.2 0.013 15.8 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein Tudor-knot PF11717.8 GBG90552.1 - 0.0018 18.1 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GBG90552.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG90552.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG90553.1 - 2.3e-59 200.6 0.4 7.8e-30 104.0 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90553.1 - 6.9e-42 141.4 2.3 7.7e-20 70.8 0.2 3.0 2 0 0 2 2 2 2 Integrase zinc binding domain Pkinase PF00069.25 GBG90553.1 - 1.3e-33 116.5 0.0 2.1e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH PF17917.1 GBG90553.1 - 2.8e-26 91.9 0.3 1.9e-13 50.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Pkinase_Tyr PF07714.17 GBG90553.1 - 7.5e-25 87.7 0.0 1.3e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase rve PF00665.26 GBG90553.1 - 5.7e-15 55.5 0.0 6.2e-06 26.4 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG90553.1 - 1.5e-14 53.8 0.2 1.9e-06 27.8 0.0 4.0 2 2 1 4 4 4 3 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG90553.1 - 7.4e-06 26.1 0.1 0.089 13.0 0.0 2.9 2 0 0 2 2 2 2 H2C2 zinc finger Chromo PF00385.24 GBG90553.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Integrin_b_cyt PF08725.11 GBG90553.1 - 0.049 13.3 0.0 4 7.2 0.0 2.6 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Retrotrans_gag PF03732.17 GBG90553.1 - 0.058 13.7 0.2 0.49 10.7 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein CLZ PF16526.5 GBG90553.1 - 1.3 9.5 4.7 5.2 7.5 0.3 3.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 GBG90553.1 - 1.6 8.0 5.8 15 4.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RT_RNaseH_2 PF17919.1 GBG90554.1 - 1.7e-26 92.2 0.0 3.9e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90554.1 - 4.3e-22 78.4 0.0 1.3e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90554.1 - 1.1e-11 44.7 0.6 2.2e-07 30.6 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ZapB PF06005.12 GBG90555.1 - 0.0013 19.1 0.3 0.0013 19.1 0.3 3.4 2 2 0 2 2 1 1 Cell division protein ZapB BRE1 PF08647.11 GBG90555.1 - 0.074 13.1 0.6 0.074 13.1 0.6 3.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.8 GBG90555.1 - 0.097 12.7 0.3 0.097 12.7 0.3 3.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CsgE PF10627.9 GBG90555.1 - 0.28 11.4 5.0 0.86 9.8 5.0 1.8 1 0 0 1 1 1 0 Curli assembly protein CsgE TMF_TATA_bd PF12325.8 GBG90555.1 - 0.33 11.2 19.5 2.5 8.3 10.2 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 GBG90555.1 - 0.45 11.0 2.4 5.7 7.4 0.0 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 GBG90555.1 - 0.93 9.6 0.0 0.93 9.6 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Beta_protein PF14350.6 GBG90555.1 - 1.2 8.5 7.1 0.74 9.2 0.3 2.1 2 0 0 2 2 2 0 Beta protein NPV_P10 PF05531.12 GBG90555.1 - 1.6 9.2 11.5 0.55 10.7 1.9 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ERM PF00769.19 GBG90555.1 - 2 8.2 28.0 2.4 7.9 26.6 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Borrelia_P83 PF05262.11 GBG90555.1 - 2.9 6.3 12.7 3.3 6.1 12.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DivIC PF04977.15 GBG90555.1 - 3.4 7.5 21.7 0.14 11.9 0.4 3.6 3 1 0 3 3 3 0 Septum formation initiator FliD_N PF02465.18 GBG90555.1 - 6.8 7.5 15.4 1.8 9.3 3.8 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus COG2 PF06148.11 GBG90555.1 - 9.5 6.3 9.4 22 5.1 2.8 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-CCHC PF00098.23 GBG90556.1 - 7.4e-08 32.1 2.7 1.7e-07 31.0 2.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG90556.1 - 0.00055 19.7 5.7 0.35 10.7 0.4 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 GBG90556.1 - 0.059 13.1 1.7 0.22 11.3 1.7 1.9 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 GBG90556.1 - 0.86 9.4 5.0 1.2 8.9 1.1 2.5 2 0 0 2 2 2 0 Zinc knuckle SDA1 PF05285.12 GBG90557.1 - 0.56 9.6 23.5 0.76 9.1 23.5 1.1 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.11 GBG90557.1 - 0.93 8.8 21.7 1.3 8.4 21.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) JAB PF01398.21 GBG90557.1 - 1.3 9.0 3.5 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Nop14 PF04147.12 GBG90557.1 - 2.6 6.2 25.8 3.7 5.6 25.8 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 GBG90557.1 - 4.5 5.3 5.3 5.5 5.0 5.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mpp10 PF04006.12 GBG90557.1 - 4.9 5.5 24.5 7 5.0 24.5 1.1 1 0 0 1 1 1 0 Mpp10 protein RRN3 PF05327.11 GBG90557.1 - 8.6 4.8 12.4 12 4.2 12.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Apt1 PF10351.9 GBG90557.1 - 8.9 5.0 11.1 13 4.4 11.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sensor PF13796.6 GBG90558.1 - 0.27 11.3 3.1 12 5.9 0.0 2.5 3 0 0 3 3 3 0 Putative sensor RVT_1 PF00078.27 GBG90559.1 - 3.7e-28 98.6 0.0 6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90559.1 - 5e-25 87.4 0.0 9.4e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90559.1 - 8e-23 80.7 0.0 1.6e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG90559.1 - 1.4 7.1 8.8 1.7 6.7 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG90559.1 - 4.1 6.6 12.4 5.6 6.2 12.4 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG90559.1 - 4.8 5.4 9.3 6.5 4.9 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase_Tyr PF07714.17 GBG90560.1 - 7.8e-40 136.8 0.0 6.7e-20 71.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG90560.1 - 1.7e-33 116.1 0.0 1.2e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Macoilin PF09726.9 GBG90560.1 - 0.0017 17.0 36.5 0.083 11.4 13.1 2.3 2 0 0 2 2 2 2 Macoilin family Cep57_CLD PF14073.6 GBG90560.1 - 0.0026 17.8 10.6 0.0026 17.8 10.6 3.9 3 2 1 4 4 3 2 Centrosome localisation domain of Cep57 MscS_porin PF12795.7 GBG90560.1 - 0.003 17.1 13.4 0.003 17.1 13.4 2.4 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain Dynein_attach_N PF15867.5 GBG90560.1 - 0.006 16.5 3.4 1.6 8.7 0.6 2.9 2 0 0 2 2 2 2 Dynein attachment factor N-terminus WD40 PF00400.32 GBG90560.1 - 0.008 17.0 0.7 1.6 9.7 0.0 4.0 4 0 0 4 4 2 1 WD domain, G-beta repeat Exonuc_VII_L PF02601.15 GBG90560.1 - 0.026 14.1 23.2 0.39 10.2 9.1 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Asp_decarbox PF02261.16 GBG90560.1 - 0.038 13.9 0.0 13 5.7 0.0 2.7 2 0 0 2 2 2 0 Aspartate decarboxylase DUF948 PF06103.11 GBG90560.1 - 0.12 12.6 9.4 1.8 8.9 1.0 2.9 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) PIN_12 PF16289.5 GBG90560.1 - 0.18 12.3 13.1 0.37 11.3 1.3 2.6 2 0 0 2 2 2 0 PIN domain Fib_alpha PF08702.10 GBG90560.1 - 0.18 12.0 24.7 1.9 8.7 11.8 3.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 GBG90560.1 - 0.51 9.4 30.7 0.29 10.2 11.2 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 GBG90560.1 - 0.65 9.2 27.2 6.7 5.9 9.0 4.5 4 0 0 4 4 4 0 TMPIT-like protein V_ATPase_I PF01496.19 GBG90560.1 - 2 6.2 16.8 0.56 8.0 4.0 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 GBG90560.1 - 3.5 6.4 19.3 1.4 7.8 2.9 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein HOOK PF05622.12 GBG90560.1 - 4 5.5 39.7 0.28 9.3 17.4 2.3 2 0 0 2 2 2 0 HOOK protein DUF3810 PF12725.7 GBG90560.1 - 4 6.7 7.2 20 4.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) FlgN PF05130.12 GBG90560.1 - 5.3 7.6 42.4 0.2 12.2 16.5 3.2 2 1 0 2 2 2 0 FlgN protein DUF5339 PF17274.2 GBG90560.1 - 5.9 7.8 18.3 7.6 7.5 3.3 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5339) DUF812 PF05667.11 GBG90560.1 - 6.2 5.6 30.0 0.97 8.2 7.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DASH_Spc34 PF08657.10 GBG90560.1 - 6.2 6.5 15.2 1.7 8.3 4.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Spc34 HMMR_N PF15905.5 GBG90560.1 - 6.5 6.1 36.3 2 7.8 16.9 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 GBG90560.1 - 9 6.3 26.6 1.4 9.0 2.9 3.8 2 2 2 4 4 4 0 Laminin Domain II DBD_Tnp_Mut PF03108.15 GBG90561.1 - 1.4e-11 44.2 0.2 2.6e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 MuDR family transposase Pkinase_Tyr PF07714.17 GBG90562.1 - 3.8e-22 78.8 0.0 6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90562.1 - 2.7e-19 69.5 0.0 3.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Rab_bind PF16704.5 GBG90562.1 - 0.032 14.3 0.3 0.077 13.0 0.3 1.6 1 0 0 1 1 1 0 Rab binding domain Pkinase_Tyr PF07714.17 GBG90563.1 - 3.4e-21 75.7 0.0 5.1e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90563.1 - 9.3e-19 67.8 0.0 1.5e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG90564.1 - 1.9e-26 92.0 0.0 3.8e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 GBG90564.1 - 2.8e-25 88.8 0.0 9.2e-25 87.1 0.0 1.9 1 0 0 1 1 1 1 DDE superfamily endonuclease RT_RNaseH PF17917.1 GBG90564.1 - 2.3e-23 82.5 0.0 4.8e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Plant_tran PF04827.14 GBG90564.1 - 1.5e-10 41.0 0.0 3.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90564.1 - 0.0016 18.2 0.2 3.7 7.1 0.1 3.5 3 0 0 3 3 3 2 Transposase DDE domain Pkinase_Tyr PF07714.17 GBG90566.1 - 4.5e-19 68.7 0.0 6.4e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90566.1 - 1.2e-15 57.6 0.0 1.7e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Sin_N PF04801.13 GBG90568.1 - 2.3e-102 343.4 0.1 4.4e-102 342.5 0.0 1.5 2 0 0 2 2 2 1 Sin-like protein conserved region MaoC_dehydratas PF01575.19 GBG90569.1 - 4.6e-21 74.6 0.0 6.5e-20 70.9 0.0 2.1 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GBG90569.1 - 4e-09 36.7 0.0 8.3e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Sin_N PF04801.13 GBG90570.1 - 1.2e-102 344.4 0.1 2.1e-102 343.6 0.0 1.4 2 0 0 2 2 2 1 Sin-like protein conserved region RT_RNaseH PF17917.1 GBG90571.1 - 4.8e-25 87.9 0.5 1.6e-24 86.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90571.1 - 8.4e-24 83.5 0.0 4.8e-23 81.1 0.0 2.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90571.1 - 3e-14 53.1 0.2 2.6e-11 43.5 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG90571.1 - 2.2e-05 24.2 0.0 4.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90571.1 - 0.00011 22.7 0.0 0.00029 21.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90571.1 - 0.0027 18.3 0.1 0.023 15.2 0.0 2.5 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF4392 PF14336.6 GBG90571.1 - 0.017 14.6 0.8 0.027 13.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Asp_protease PF09668.10 GBG90571.1 - 0.045 13.5 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG90571.1 - 0.046 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Peptidase_M50 PF02163.22 GBG90572.1 - 2.2e-56 190.9 0.0 2.8e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 GBG90572.1 - 5e-05 23.5 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GBG90572.1 - 0.00019 21.2 0.1 0.00045 20.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GBG90572.1 - 0.0015 18.8 1.8 0.0027 18.0 0.1 2.3 2 1 1 3 3 3 1 PDZ domain SPX PF03105.19 GBG90572.1 - 0.19 11.6 5.1 0.27 11.1 5.1 1.2 1 0 0 1 1 1 0 SPX domain AAA PF00004.29 GBG90573.1 - 1.1e-53 181.2 0.0 2.5e-37 128.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG90573.1 - 2.2e-06 28.2 5.3 0.011 16.1 0.0 4.1 2 2 1 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.17 GBG90573.1 - 7.4e-05 22.5 0.1 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 GBG90573.1 - 7.6e-05 22.9 0.0 0.099 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GBG90573.1 - 9.5e-05 22.1 5.5 0.35 10.4 0.1 4.2 2 2 1 4 4 4 1 AAA domain AAA_18 PF13238.6 GBG90573.1 - 0.00011 22.8 0.0 0.87 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GBG90573.1 - 0.0011 19.3 0.0 1.3 9.5 0.0 2.8 2 1 0 2 2 2 2 RNA helicase AAA_22 PF13401.6 GBG90573.1 - 0.0014 18.9 0.6 7.5 6.8 0.1 4.2 2 2 1 4 4 4 0 AAA domain NACHT PF05729.12 GBG90573.1 - 0.0026 17.7 0.0 0.086 12.8 0.0 2.7 2 1 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 GBG90573.1 - 0.0035 17.3 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 GBG90573.1 - 0.0055 16.6 0.0 0.34 10.8 0.0 2.8 4 0 0 4 4 3 1 Rad17 P-loop domain AAA_2 PF07724.14 GBG90573.1 - 0.014 15.6 0.0 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 GBG90573.1 - 0.023 14.7 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GBG90573.1 - 0.027 13.8 0.2 0.82 9.0 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 GBG90573.1 - 0.047 13.4 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 GBG90573.1 - 0.052 13.5 0.0 9 6.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 GBG90573.1 - 0.054 12.8 0.0 4 6.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Bac_DnaA PF00308.18 GBG90573.1 - 0.065 13.1 0.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein ABC_tran PF00005.27 GBG90573.1 - 0.075 13.6 0.0 0.52 10.8 0.0 2.3 3 0 0 3 3 2 0 ABC transporter RuvB_N PF05496.12 GBG90573.1 - 0.087 12.6 0.0 15 5.3 0.0 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain CobU PF02283.16 GBG90573.1 - 0.088 12.4 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TniB PF05621.11 GBG90573.1 - 0.09 12.2 0.0 1.8 7.9 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 GBG90573.1 - 0.095 12.2 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 GBG90573.1 - 0.14 12.2 0.2 19 5.3 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE WD40 PF00400.32 GBG90574.1 - 1.7e-07 31.8 7.1 2.6 9.1 0.0 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat FAM184 PF15665.5 GBG90574.1 - 0.085 12.6 14.8 0.16 11.8 14.8 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Apolipoprotein PF01442.18 GBG90574.1 - 0.16 11.8 10.4 0.27 11.1 10.4 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1319 PF07028.11 GBG90574.1 - 0.51 10.6 4.6 10 6.4 4.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) RRF PF01765.19 GBG90574.1 - 0.6 10.1 9.6 0.8 9.6 8.7 1.6 1 1 0 1 1 1 0 Ribosome recycling factor TcpS PF17456.2 GBG90576.1 - 0.047 13.8 9.6 0.31 11.1 0.5 2.3 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S LCD1 PF09798.9 GBG90576.1 - 0.11 11.0 3.4 0.11 11.0 3.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Takusan PF04822.13 GBG90576.1 - 0.28 11.1 10.1 0.19 11.6 1.7 2.4 2 0 0 2 2 2 0 Takusan Selenoprotein_S PF06936.11 GBG90576.1 - 8.4 6.2 19.1 6 6.6 4.3 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) gag-asp_proteas PF13975.6 GBG90577.1 - 7.9e-08 32.8 0.2 2.7e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90577.1 - 3.2e-05 24.5 0.2 0.00012 22.7 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG90577.1 - 0.00058 19.7 0.6 0.0012 18.7 0.6 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG90577.1 - 0.0052 17.0 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein RVP PF00077.20 GBG90577.1 - 0.0072 16.6 0.0 0.03 14.6 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Presenilin PF01080.17 GBG90577.1 - 0.38 9.5 1.1 0.61 8.8 1.1 1.3 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 GBG90577.1 - 2.9 7.6 5.7 1 9.0 2.5 1.9 2 0 0 2 2 2 0 FAM176 family RXLR PF16810.5 GBG90577.1 - 3.9 7.9 5.2 53 4.2 1.5 2.9 3 0 0 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity GCV_T_C PF08669.11 GBG90578.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain TMF_DNA_bd PF12329.8 GBG90579.1 - 0.13 12.3 7.4 0.28 11.2 6.9 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 GBG90579.1 - 0.15 12.3 1.6 0.24 11.6 1.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.8 GBG90579.1 - 0.16 12.1 2.1 0.31 11.2 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3287 PF11690.8 GBG90579.1 - 0.27 11.0 7.2 0.52 10.0 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Tn7_Tnp_TnsA_N PF08722.11 GBG90579.1 - 4.4 7.6 5.9 4.2e+02 1.2 5.9 2.5 1 1 0 1 1 1 0 TnsA endonuclease N terminal RVT_1 PF00078.27 GBG90580.1 - 1.6e-17 63.8 0.1 2.7e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG90580.1 - 0.015 15.9 0.0 0.038 14.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Tup_N PF08581.10 GBG90581.1 - 0.0003 21.0 7.7 0.057 13.7 0.8 2.4 1 1 1 2 2 2 2 Tup N-terminal DUF4515 PF14988.6 GBG90581.1 - 0.0043 16.9 9.5 0.0077 16.1 9.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) DUF1843 PF08898.10 GBG90581.1 - 0.0059 17.1 3.5 0.015 15.8 2.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF1843) Metal_resist PF13801.6 GBG90581.1 - 0.032 14.4 4.9 0.09 13.0 4.9 1.8 1 0 0 1 1 1 0 Heavy-metal resistance DUF16 PF01519.16 GBG90581.1 - 0.47 11.0 7.7 0.16 12.5 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Prominin PF05478.11 GBG90581.1 - 0.7 7.8 4.2 0.84 7.5 4.2 1.1 1 0 0 1 1 1 0 Prominin FAM184 PF15665.5 GBG90581.1 - 1 9.1 20.1 3.7 7.3 19.8 1.9 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF1515 PF07439.11 GBG90581.1 - 2.7 8.0 7.8 0.95 9.5 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Med26 PF08711.11 GBG90581.1 - 3.6 7.7 8.1 4.4 7.4 1.4 3.1 2 1 1 3 3 3 0 TFIIS helical bundle-like domain Phasin PF05597.11 GBG90581.1 - 6 6.9 15.4 0.33 11.0 8.7 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) zf-RING_11 PF17123.5 GBG90582.1 - 8e-10 38.3 0.7 1.9e-09 37.1 0.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GBG90582.1 - 1.2e-08 35.1 5.2 1.2e-08 35.1 5.2 2.1 2 0 0 2 2 1 1 Ring finger domain VWA PF00092.28 GBG90582.1 - 1.6e-06 28.5 0.0 8.5e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-C3HC4_2 PF13923.6 GBG90582.1 - 4.7e-05 23.1 6.1 0.00014 21.6 6.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) VWA_3 PF13768.6 GBG90582.1 - 6.2e-05 23.0 0.4 0.00017 21.5 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_UBOX PF13445.6 GBG90582.1 - 0.00081 19.4 5.6 0.0036 17.3 5.6 2.2 1 0 0 1 1 1 1 RING-type zinc-finger PRCC PF10253.9 GBG90582.1 - 0.00089 20.1 0.1 0.00089 20.1 0.1 5.3 4 1 2 6 6 2 1 Mitotic checkpoint regulator, MAD2B-interacting zf-C3HC4 PF00097.25 GBG90582.1 - 0.0012 18.7 4.4 0.0012 18.7 4.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) BUD22 PF09073.10 GBG90582.1 - 0.0013 18.2 48.8 0.0013 18.2 48.8 6.7 5 2 0 5 5 2 1 BUD22 zf-rbx1 PF12678.7 GBG90582.1 - 0.0025 18.1 8.3 0.01 16.1 8.3 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GBG90582.1 - 0.034 14.0 8.4 0.11 12.4 8.4 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 GBG90582.1 - 0.066 13.1 4.3 0.2 11.6 4.3 1.9 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 GBG90582.1 - 0.18 11.8 11.4 0.013 15.4 5.9 2.1 2 0 0 2 2 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GBG90582.1 - 0.29 10.8 6.4 0.93 9.2 6.4 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GBG90582.1 - 1.7 8.5 11.2 0.56 10.1 7.8 2.1 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 GBG90582.1 - 2.4 8.2 4.5 7.8 6.6 4.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1690 PF07956.11 GBG90583.1 - 0.013 15.9 2.5 0.014 15.8 1.0 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Cmc1 PF08583.10 GBG90583.1 - 0.13 12.3 0.4 0.13 12.3 0.4 2.3 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 GBG90583.1 - 0.72 10.2 4.2 1.4 9.4 4.2 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) WD40 PF00400.32 GBG90584.1 - 1.6e-18 66.7 14.3 0.0021 18.9 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG90584.1 - 1.1e-05 25.7 0.0 0.75 10.1 0.0 3.7 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DctP PF03480.13 GBG90584.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 AICARFT_IMPCHas PF01808.18 GBG90585.1 - 1.2e-108 363.1 0.0 1.5e-108 362.7 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 GBG90585.1 - 3.8e-24 84.7 0.0 9.3e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain DNA_processg_A PF02481.15 GBG90585.1 - 0.13 11.5 0.2 0.24 10.6 0.2 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A NDK PF00334.19 GBG90586.1 - 9.6e-22 77.4 0.0 1.8e-11 44.2 0.0 2.4 1 1 1 2 2 2 2 Nucleoside diphosphate kinase Ish1 PF10281.9 GBG90587.1 - 0.0037 17.5 0.7 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein PIN_6 PF17146.4 GBG90588.1 - 1.6e-24 86.2 0.2 2.8e-24 85.4 0.2 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 GBG90588.1 - 5.5e-21 74.5 0.2 9.7e-21 73.7 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L37e PF01907.19 GBG90588.1 - 0.21 11.8 1.4 0.46 10.7 1.4 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e zf-NADH-PPase PF09297.11 GBG90588.1 - 0.25 11.0 4.1 1.3 8.7 0.1 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RVT_1 PF00078.27 GBG90589.1 - 8e-35 120.4 0.0 1.6e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG90589.1 - 4.3e-06 26.4 0.1 9.5e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 GBG90589.1 - 5e-05 23.9 2.6 5e-05 23.9 2.6 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase NgoMIV_restric PF09015.10 GBG90589.1 - 0.056 12.6 0.2 0.099 11.7 0.2 1.3 1 0 0 1 1 1 0 NgoMIV restriction enzyme Phi-29_GP4 PF05464.11 GBG90589.1 - 0.082 13.2 0.2 0.25 11.6 0.2 1.8 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) DUF3309 PF11752.8 GBG90589.1 - 0.093 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) CHAT PF12770.7 GBG90590.1 - 0.15 11.5 6.2 0.067 12.6 4.3 1.3 1 1 0 1 1 1 0 CHAT domain Caldesmon PF02029.15 GBG90590.1 - 0.45 9.2 59.2 0.48 9.1 59.2 1.0 1 0 0 1 1 1 0 Caldesmon PNISR PF15996.5 GBG90590.1 - 2 8.7 54.6 2.7 8.2 54.6 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR BAF1_ABF1 PF04684.13 GBG90590.1 - 5.4 6.0 41.0 5.9 5.8 41.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF5523 PF17661.1 GBG90590.1 - 5.8 6.5 48.0 6.3 6.4 48.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Ndc1_Nup PF09531.10 GBG90590.1 - 5.9 5.4 25.3 6.1 5.4 25.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 GBG90590.1 - 7.1 5.3 30.8 7.1 5.3 30.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PAT1 PF09770.9 GBG90590.1 - 9.7 4.3 41.5 10 4.2 41.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FGGY_C PF02782.16 GBG90594.1 - 3.4e-16 59.6 0.0 4.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pyr_redox_2 PF07992.14 GBG90596.1 - 8.3e-49 166.4 0.8 1.3e-48 165.8 0.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SufE PF02657.15 GBG90596.1 - 1.2e-34 118.8 0.0 5.5e-34 116.6 0.0 2.2 2 0 0 2 2 2 1 Fe-S metabolism associated domain NadA PF02445.16 GBG90596.1 - 3.3e-31 108.6 2.8 8.7e-31 107.2 0.8 2.1 2 0 0 2 2 2 1 Quinolinate synthetase A protein Pyr_redox_dim PF02852.22 GBG90596.1 - 1.7e-20 73.3 4.0 1.3e-14 54.4 0.1 3.8 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GBG90596.1 - 9.8e-16 58.1 2.5 7.3e-13 48.9 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG90596.1 - 1.7e-07 30.8 0.1 0.0003 20.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GBG90596.1 - 2.7e-05 23.4 1.5 6.2e-05 22.3 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GBG90596.1 - 0.0013 17.6 0.2 0.0032 16.2 0.2 1.7 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 GBG90596.1 - 0.002 18.3 1.2 0.03 14.6 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG90596.1 - 0.012 15.2 1.4 0.12 11.9 0.3 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 GBG90596.1 - 0.023 13.9 0.2 0.052 12.8 0.2 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 GBG90596.1 - 0.038 13.3 0.4 0.062 12.6 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 GBG90596.1 - 0.091 11.8 0.6 0.17 10.9 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A RVT_connect PF06815.13 GBG90596.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase connection domain SHIPPO-rpt PF07004.12 GBG90597.1 - 6.3e-23 80.6 81.7 0.0016 19.3 0.1 12.6 12 1 0 12 12 12 9 Sperm-tail PG-rich repeat ECR1_N PF14382.6 GBG90597.1 - 2.1 8.2 17.0 25 4.8 0.0 7.2 9 0 0 9 9 9 0 Exosome complex exonuclease RRP4 N-terminal region RT_RNaseH PF17917.1 GBG90598.1 - 4e-28 97.8 0.3 9.7e-28 96.5 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90598.1 - 9.7e-21 73.7 0.0 2e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90598.1 - 7.2e-20 70.9 0.0 1.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90598.1 - 7.8e-09 35.8 0.0 2e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90598.1 - 0.00019 21.6 0.0 0.00054 20.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG90598.1 - 0.015 15.6 0.1 0.06 13.6 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein SANT_DAMP1_like PF16282.5 GBG90598.1 - 0.1 12.8 2.4 30 4.9 0.1 3.7 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 PIH1_CS PF18201.1 GBG90599.1 - 1.1e-13 51.4 0.2 1.9e-13 50.6 0.2 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain SPT6_acidic PF14632.6 GBG90599.1 - 0.066 13.8 14.2 0.11 13.1 14.2 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 BLM10_N PF16547.5 GBG90599.1 - 0.21 11.9 2.3 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, N-terminal Nop25 PF09805.9 GBG90599.1 - 0.39 11.2 16.3 0.076 13.5 12.4 1.7 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) YqfQ PF14181.6 GBG90599.1 - 4.3 7.5 5.3 6 7.0 5.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein Rrn6 PF10214.9 GBG90599.1 - 7.1 5.0 5.5 9 4.6 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Nop PF01798.18 GBG90601.1 - 2.1e-78 262.9 0.1 6e-78 261.5 0.0 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 GBG90601.1 - 6.6e-43 146.5 1.2 1.2e-42 145.6 1.2 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain zf-C3HC4_2 PF13923.6 GBG90603.1 - 0.00075 19.3 1.5 0.002 17.9 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG90603.1 - 0.00079 19.3 0.5 0.0069 16.3 0.5 2.2 1 1 0 1 1 1 1 zinc-RING finger domain Clathrin PF00637.20 GBG90603.1 - 0.0014 18.5 0.5 0.0029 17.5 0.1 1.7 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.6 GBG90603.1 - 0.0015 18.8 0.4 0.0071 16.7 0.1 2.2 2 0 0 2 2 2 1 Ring finger domain Pox_A_type_inc PF04508.12 GBG90603.1 - 0.0015 18.2 2.1 0.49 10.3 0.3 2.7 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat zf-RING_UBOX PF13445.6 GBG90603.1 - 0.0037 17.3 1.8 0.0039 17.2 0.1 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG90603.1 - 0.0075 16.1 0.2 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GBG90603.1 - 0.0093 16.2 0.0 0.035 14.4 0.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain Vps39_2 PF10367.9 GBG90603.1 - 0.011 16.2 1.8 0.016 15.6 0.0 2.2 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Occludin_ELL PF07303.13 GBG90603.1 - 0.014 16.1 0.2 0.17 12.6 0.0 2.2 2 0 0 2 2 2 0 Occludin homology domain Nup54_57_C PF18570.1 GBG90603.1 - 0.019 14.6 0.5 0.045 13.3 0.1 1.9 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain SlyX PF04102.12 GBG90603.1 - 0.02 15.5 0.5 7.1 7.3 0.1 2.4 2 0 0 2 2 2 0 SlyX zf-RING_11 PF17123.5 GBG90603.1 - 0.038 13.7 2.3 0.038 13.7 2.3 2.3 2 0 0 2 2 2 0 RING-like zinc finger DUF4140 PF13600.6 GBG90603.1 - 0.047 14.1 1.3 9.8 6.7 0.0 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 GBG90603.1 - 0.063 13.6 1.0 3.6 8.0 0.1 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain CENP-H PF05837.12 GBG90603.1 - 0.26 11.7 4.3 12 6.3 0.1 3.1 3 0 0 3 3 3 0 Centromere protein H (CENP-H) SpoOE-like PF09388.10 GBG90603.1 - 0.5 10.3 3.5 0.51 10.3 0.3 2.3 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein zf-C3H2C3 PF17122.5 GBG90603.1 - 4.3 7.5 8.0 0.53 10.4 3.5 1.8 2 0 0 2 2 2 0 Zinc-finger XhlA PF10779.9 GBG90603.1 - 7.7 6.8 7.3 2.4 8.4 0.4 2.6 3 0 0 3 3 3 0 Haemolysin XhlA DNA_pol_A PF00476.20 GBG90604.1 - 1.4e-13 50.6 0.0 3.6e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 GBG90604.1 - 1.5e-11 44.3 0.0 4.5e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 3'-5' exonuclease CPL PF08144.11 GBG90606.1 - 1.1e-14 55.0 3.7 9.7e-06 26.0 0.0 6.1 5 2 1 6 6 6 3 CPL (NUC119) domain PUF PF00806.19 GBG90606.1 - 6.4e-08 31.9 0.1 0.016 14.8 0.0 4.5 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat TFIIF_alpha PF05793.12 GBG90606.1 - 5.2 5.5 23.0 9.6 4.7 23.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.25 GBG90607.1 - 1.3e-64 218.1 0.0 2.6e-64 217.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG90607.1 - 4e-30 105.0 0.0 4.8e-28 98.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG90607.1 - 0.00014 21.3 0.7 0.0018 17.7 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 GBG90607.1 - 0.0021 18.1 0.5 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GBG90607.1 - 0.0038 16.2 0.7 0.0062 15.5 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 GBG90607.1 - 0.0067 16.1 0.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GBG90607.1 - 0.0088 15.7 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 GBG90607.1 - 0.011 14.6 0.7 0.03 13.1 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 GBG90607.1 - 0.054 12.8 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4795 PF16043.5 GBG90607.1 - 0.078 12.6 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DDE_Tnp_4 PF13359.6 GBG90609.1 - 0.034 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.6 GBG90610.1 - 8.3e-05 22.9 0.2 0.00019 21.8 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG90610.1 - 0.074 13.2 0.3 0.16 12.2 0.3 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain RT_RNaseH PF17917.1 GBG90611.1 - 2.8e-11 43.6 0.0 7.6e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90611.1 - 1.1e-08 35.0 0.0 2.8e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG90611.1 - 0.014 15.7 1.7 0.054 13.8 0.0 2.8 3 1 0 3 3 3 0 Retrotransposon gag protein DUF3752 PF12572.8 GBG90611.1 - 7.2 7.1 11.1 0.35 11.4 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) zf-CCHC PF00098.23 GBG90612.1 - 0.00039 20.4 0.1 0.00073 19.5 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle DivIC PF04977.15 GBG90612.1 - 0.015 15.0 1.4 0.015 15.0 1.4 5.8 6 2 0 6 6 6 0 Septum formation initiator PikAIV_N PF18605.1 GBG90612.1 - 1 9.0 19.6 4 7.1 0.3 4.6 4 0 0 4 4 4 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain CCDC92 PF14916.6 GBG90612.1 - 1.4 8.8 14.9 19 5.1 0.1 5.6 5 1 1 6 6 6 0 Coiled-coil domain of unknown function C2 PF00168.30 GBG90613.1 - 6.6e-08 32.8 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF659 PF04937.15 GBG90615.1 - 2.1e-11 43.9 0.0 3.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) S-AdoMet_synt_C PF02773.16 GBG90618.1 - 3.3e-43 147.0 0.0 4.3e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 GBG90618.1 - 2.6e-26 92.2 0.1 5.8e-26 91.1 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_N PF00438.20 GBG90619.1 - 6.5e-43 145.5 0.2 1.3e-42 144.5 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 GBG90619.1 - 7.6e-30 103.6 0.0 1.3e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_C PF02773.16 GBG90619.1 - 7.3e-23 81.1 0.0 1.1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain Chitin_bind_4 PF00379.23 GBG90619.1 - 0.073 13.6 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Insect cuticle protein DnaJ_CXXCXGXG PF00684.19 GBG90619.1 - 0.15 12.5 2.2 0.32 11.4 2.2 1.5 1 0 0 1 1 1 0 DnaJ central domain C1_1 PF00130.22 GBG90619.1 - 0.18 11.7 0.5 0.7 9.8 0.1 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) S-AdoMet_synt_M PF02772.16 GBG90620.1 - 1.1e-42 145.1 0.0 1.9e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG90620.1 - 1.1e-42 144.7 0.2 1.9e-42 144.0 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Chitin_bind_4 PF00379.23 GBG90620.1 - 0.062 13.8 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Insect cuticle protein DnaJ_CXXCXGXG PF00684.19 GBG90620.1 - 0.09 13.1 1.8 0.18 12.2 1.8 1.4 1 0 0 1 1 1 0 DnaJ central domain C1_1 PF00130.22 GBG90620.1 - 0.16 11.9 0.4 0.75 9.7 0.1 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 GBG90620.1 - 0.47 10.0 2.0 0.68 9.5 0.2 2.1 2 0 0 2 2 2 0 PHD-finger SDA1 PF05285.12 GBG90621.1 - 0.039 13.4 13.7 0.046 13.1 13.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG90621.1 - 0.25 9.5 17.7 0.29 9.3 17.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG90621.1 - 0.48 8.7 11.9 0.59 8.4 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GBG90621.1 - 1.7 8.0 11.1 2.1 7.7 11.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Astro_capsid_p PF12226.8 GBG90621.1 - 3.6 6.7 12.7 4.5 6.3 12.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein LAP1C PF05609.12 GBG90621.1 - 3.6 6.6 9.6 4.4 6.3 9.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RR_TM4-6 PF06459.12 GBG90621.1 - 5.2 6.8 11.3 7.8 6.2 11.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 GBG90621.1 - 7 4.6 21.9 8.8 4.3 21.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 GBG90621.1 - 8.9 5.0 7.1 11 4.7 7.1 1.1 1 0 0 1 1 1 0 Presenilin DUF659 PF04937.15 GBG90622.1 - 0.094 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) SKG6 PF08693.10 GBG90623.1 - 6.9e-05 22.2 0.3 0.00017 20.9 0.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Lactonase PF10282.9 GBG90623.1 - 0.0005 19.4 0.0 0.035 13.3 0.0 3.0 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 GBG90623.1 - 0.01 16.0 0.0 3.2 8.0 0.0 3.0 3 0 0 3 3 3 1 Arylesterase NHL PF01436.21 GBG90623.1 - 0.02 14.9 0.1 4.1 7.6 0.0 3.8 4 0 0 4 4 4 0 NHL repeat SGL PF08450.12 GBG90623.1 - 0.021 14.4 0.0 4.1 6.9 0.0 3.1 1 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 GBG90623.1 - 0.14 12.3 0.0 18 5.6 0.0 3.1 3 0 0 3 3 3 0 Strictosidine synthase PQQ_3 PF13570.6 GBG90623.1 - 0.97 10.0 2.9 8.4 7.0 0.1 3.4 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.32 GBG90623.1 - 3.3 8.7 4.5 3.3 8.7 0.1 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Myb_DNA-bind_4 PF13837.6 GBG90625.1 - 0.14 12.6 0.5 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Spo7 PF03907.13 GBG90626.1 - 0.057 12.9 0.6 9.7 5.6 0.2 2.7 2 1 1 3 3 3 0 Spo7-like protein TMEM51 PF15345.6 GBG90626.1 - 0.074 12.9 0.4 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 SGL PF08450.12 GBG90626.1 - 0.084 12.4 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region EIF_2_alpha PF07541.12 GBG90627.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Asp_protease_2 PF13650.6 GBG90628.1 - 0.034 14.8 0.0 0.12 13.0 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG90628.1 - 0.085 12.5 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG90628.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease 2OG-FeII_Oxy_2 PF13532.6 GBG90629.1 - 0.037 14.2 2.7 0.11 12.7 2.7 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 GBG90630.1 - 2.3e-28 99.1 0.0 6.5e-28 97.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.10 GBG90630.1 - 5.7e-26 91.1 1.1 2.6e-25 89.0 0.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) CDT1 PF08839.11 GBG90630.1 - 1.9e-11 44.6 0.0 5.6e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 DNA replication factor CDT1 like Helicase_C PF00271.31 GBG90630.1 - 3.8e-09 36.9 0.0 8.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ubiquitin PF00240.23 GBG90630.1 - 6.7e-05 22.6 0.1 0.00016 21.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family ResIII PF04851.15 GBG90630.1 - 0.00059 19.9 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rad60-SLD PF11976.8 GBG90630.1 - 0.00098 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Bestrophin PF01062.21 GBG90631.1 - 1.5e-19 70.5 1.6 2e-19 70.1 1.6 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PTP_N PF12453.8 GBG90631.1 - 0.1 12.3 1.8 0.4 10.4 1.8 2.0 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal RT_RNaseH PF17917.1 GBG90632.1 - 4.1e-21 75.2 0.0 7.2e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90632.1 - 1.9e-18 66.3 0.0 3.7e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90632.1 - 2.2e-14 53.3 0.1 7.1e-14 51.7 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90632.1 - 6.7e-14 52.1 0.0 1.6e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90632.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger SlyX PF04102.12 GBG90632.1 - 0.082 13.5 0.1 3.1 8.5 0.0 3.7 2 0 0 2 2 2 0 SlyX WD40 PF00400.32 GBG90633.1 - 1.2e-29 101.8 15.5 9.4e-06 26.3 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG90633.1 - 5.4e-07 29.8 0.1 0.26 11.6 0.0 4.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG90633.1 - 0.0005 18.9 3.9 0.8 8.3 0.1 3.6 1 1 1 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 GBG90633.1 - 0.027 13.8 0.0 4.4 6.5 0.0 2.3 1 1 0 2 2 2 0 WD40-like domain CDC27 PF09507.10 GBG90633.1 - 1.2 8.4 10.0 1.6 8.0 10.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Bestrophin PF01062.21 GBG90634.1 - 1.2e-19 70.8 1.4 1.6e-19 70.4 1.4 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF1011 PF06237.12 GBG90634.1 - 0.77 10.1 6.0 0.78 10.1 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) DUF659 PF04937.15 GBG90635.1 - 1.3e-16 60.9 0.0 1.9e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG90636.1 - 0.00016 21.6 1.8 0.00026 20.9 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle XRN_M PF17846.1 GBG90636.1 - 0.41 9.6 6.6 0.57 9.1 6.6 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Atg14 PF10186.9 GBG90636.1 - 2.5 7.1 9.8 3.3 6.7 9.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Dimer_Tnp_hAT PF05699.14 GBG90637.1 - 2.3e-08 33.7 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Med13_N PF11597.8 GBG90637.1 - 0.084 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal RT_RNaseH_2 PF17919.1 GBG90638.1 - 4.1e-24 84.5 0.0 8.6e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90638.1 - 1.7e-18 66.8 0.0 3.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90638.1 - 5.1e-12 45.8 0.0 8.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF966 PF06136.13 GBG90639.1 - 4.1 7.0 17.4 6.1 6.5 17.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Pkinase PF00069.25 GBG90641.1 - 1.2e-19 70.7 0.0 1.7e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG90641.1 - 4.6e-15 55.6 0.0 7.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CDC45 PF02724.14 GBG90642.1 - 0.032 12.6 15.3 0.04 12.2 15.3 1.0 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG90642.1 - 0.15 11.3 24.1 0.2 11.0 24.1 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG90642.1 - 0.53 8.4 23.4 0.61 8.2 23.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 GBG90642.1 - 0.64 9.4 3.2 0.95 8.8 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Vfa1 PF08432.10 GBG90642.1 - 0.75 10.1 9.5 1.1 9.5 9.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 GBG90642.1 - 0.88 8.9 22.8 1 8.7 22.8 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GBG90642.1 - 1.5 7.5 9.2 1.8 7.2 9.2 1.2 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 GBG90642.1 - 4.9 6.6 14.1 6.8 6.2 14.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF659 PF04937.15 GBG90643.1 - 0.0032 17.3 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Trypan_PARP PF05887.11 GBG90643.1 - 0.22 11.5 8.9 0.68 9.9 8.9 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.12 GBG90643.1 - 2.6 6.2 9.7 3.9 5.5 9.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG90643.1 - 7 4.8 14.0 10 4.3 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG90644.1 - 4.5e-17 62.3 0.0 7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90644.1 - 3.5e-06 26.7 0.1 7e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase_Tyr PF07714.17 GBG90645.1 - 1.2e-36 126.4 0.0 1.7e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90645.1 - 1.2e-34 119.9 0.0 1.8e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG90645.1 - 0.15 12.0 0.0 0.87 9.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family ADP_ribosyl_GH PF03747.14 GBG90646.1 - 6.3 6.4 6.0 35 4.0 6.0 2.4 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase CSRNP_N PF16019.5 GBG90646.1 - 7 6.5 9.9 0.35 10.8 2.0 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus RVT_1 PF00078.27 GBG90647.1 - 3.1e-31 108.6 0.1 5e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90647.1 - 1.4e-27 95.7 0.1 2.7e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90647.1 - 3.7e-17 62.2 0.1 7.5e-17 61.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90647.1 - 9.2e-14 51.6 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90647.1 - 0.003 17.7 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DUF5095 PF17016.5 GBG90647.1 - 0.045 13.4 0.3 0.076 12.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) PKcGMP_CC PF16808.5 GBG90650.1 - 0.023 14.6 1.7 0.074 12.9 0.4 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Nsp1_C PF05064.13 GBG90650.1 - 0.052 13.4 0.6 0.093 12.5 0.4 1.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region LMBR1 PF04791.16 GBG90650.1 - 0.076 11.9 0.1 0.088 11.7 0.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5593 PF18007.1 GBG90650.1 - 0.18 12.5 1.2 0.23 12.2 0.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5593) APG6_N PF17675.1 GBG90650.1 - 0.57 10.7 6.5 7.2 7.1 6.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Gon7 PF08738.10 GBG90651.1 - 0.028 14.5 0.0 0.028 14.5 0.0 2.9 2 1 1 3 3 3 0 Gon7 family Adaptin_binding PF10199.9 GBG90651.1 - 0.033 14.8 4.8 0.1 13.2 4.7 1.8 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SlyX PF04102.12 GBG90651.1 - 0.051 14.2 21.9 0.083 13.5 2.3 3.9 3 1 1 4 4 4 0 SlyX AP_endonuc_2 PF01261.24 GBG90651.1 - 0.051 13.0 2.7 2.5 7.5 1.4 2.2 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel DUF3332 PF11810.8 GBG90651.1 - 0.29 10.8 4.0 0.5 10.0 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) HAP1_N PF04849.13 GBG90651.1 - 0.52 9.5 24.8 0.81 8.8 21.4 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region FUSC PF04632.12 GBG90651.1 - 0.61 8.6 7.3 0.86 8.1 7.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AHSP PF09236.10 GBG90651.1 - 0.91 10.0 6.4 16 6.0 0.8 2.7 1 1 1 2 2 2 0 Alpha-haemoglobin stabilising protein LPP PF04728.13 GBG90651.1 - 1.6 9.2 8.7 0.54 10.7 1.6 3.2 3 1 1 4 4 3 0 Lipoprotein leucine-zipper DUF5082 PF16888.5 GBG90651.1 - 2.8 8.2 17.7 5.9 7.2 12.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Fez1 PF06818.15 GBG90651.1 - 3 8.2 26.3 43 4.5 26.3 2.0 1 1 0 1 1 1 0 Fez1 Baculo_PEP_C PF04513.12 GBG90651.1 - 5.3 7.1 6.5 57 3.7 3.0 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF730 PF05325.11 GBG90651.1 - 9.9 6.2 10.1 3.1 7.8 2.6 3.3 1 1 2 4 4 4 0 Protein of unknown function (DUF730) RVT_1 PF00078.27 GBG90653.1 - 4.1e-34 118.0 0.2 8.2e-34 117.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90653.1 - 1.4e-31 108.5 0.0 8.4e-31 106.0 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90653.1 - 2.1e-30 105.1 0.0 5.4e-30 103.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG90653.1 - 6e-07 29.3 0.0 1.5e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90653.1 - 2.4e-06 28.1 0.1 8.5e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90653.1 - 0.00044 20.8 0.1 0.0015 19.1 0.1 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG90653.1 - 0.00062 19.6 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG90653.1 - 0.0099 15.7 0.0 0.026 14.3 0.0 1.7 1 1 0 1 1 1 1 Aspartyl protease Phage_GPO PF05929.11 GBG90653.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RskA PF10099.9 GBG90654.1 - 0.0032 17.8 0.4 0.0081 16.5 0.4 1.7 1 0 0 1 1 1 1 Anti-sigma-K factor rskA KELK PF15796.5 GBG90655.1 - 0.028 14.9 3.0 0.028 14.9 3.0 5.8 5 1 0 5 5 5 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase S_layer_N PF05123.12 GBG90655.1 - 0.035 14.0 1.0 0.056 13.3 1.0 1.4 1 0 0 1 1 1 0 S-layer like family, N-terminal region DNA_primase_S PF01896.19 GBG90656.1 - 1.4e-57 194.6 0.6 2.7e-57 193.7 0.6 1.5 1 0 0 1 1 1 1 DNA primase small subunit G_glu_transpept PF01019.21 GBG90657.1 - 8.7e-173 575.8 0.0 1e-172 575.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HAGH_C PF16123.5 GBG90658.1 - 2.6e-26 91.9 0.1 4.3e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 GBG90658.1 - 6.7e-21 75.2 3.8 9.6e-21 74.7 3.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GBG90658.1 - 0.046 13.2 0.4 0.1 12.1 0.4 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain WD40 PF00400.32 GBG90659.1 - 3.6e-42 141.5 14.6 1.3e-08 35.3 0.0 10.3 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.12 GBG90659.1 - 4.5e-26 91.2 0.6 6.9e-26 90.7 0.6 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 GBG90659.1 - 9e-20 70.8 0.0 0.067 13.5 0.0 8.7 4 2 5 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG90659.1 - 0.00048 19.2 0.0 3.6 6.5 0.0 4.1 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GBG90659.1 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 GBG90659.1 - 0.01 14.5 1.9 4 6.0 0.1 3.0 1 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40_3 PF15911.5 GBG90659.1 - 0.025 14.6 0.0 9 6.4 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat BBS2_Mid PF14783.6 GBG90659.1 - 0.083 12.9 0.0 10 6.2 0.0 3.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region rve PF00665.26 GBG90660.1 - 1.2e-13 51.3 0.1 3e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG90660.1 - 0.0022 18.2 0.7 0.013 15.7 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF1564 PF07600.11 GBG90660.1 - 0.0066 16.1 0.1 0.029 14.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1564) AA_permease_2 PF13520.6 GBG90661.1 - 4.6e-66 223.4 45.1 6e-66 223.0 45.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GBG90661.1 - 1.8e-45 155.5 40.2 2.2e-45 155.1 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GBG90661.1 - 2.2e-05 24.5 3.8 2.2e-05 24.5 3.8 3.5 4 0 0 4 4 4 1 C-terminus of AA_permease Rad17 PF03215.15 GBG90662.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF659 PF04937.15 GBG90663.1 - 0.00018 21.4 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Miff PF05644.11 GBG90663.1 - 0.22 11.1 7.3 0.35 10.5 7.3 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff mTERF PF02536.14 GBG90665.1 - 1.2e-76 257.7 0.0 1.3e-63 214.8 0.0 2.5 1 1 1 2 2 2 2 mTERF Herpes_UL47 PF03362.13 GBG90665.1 - 0.2 10.4 0.1 0.32 9.7 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL47 protein CDC45 PF02724.14 GBG90665.1 - 4.5 5.4 12.3 8.1 4.6 12.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG90666.1 - 3.1e-09 36.9 0.1 7.7e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90666.1 - 0.00013 21.7 0.2 0.0003 20.5 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region dsrm PF00035.26 GBG90666.1 - 0.0049 17.5 1.2 0.016 15.9 0.5 2.3 2 1 0 2 2 2 1 Double-stranded RNA binding motif Cwf_Cwc_15 PF04889.12 GBG90666.1 - 0.016 14.9 6.5 0.033 13.9 6.5 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PHM7_cyt PF14703.6 GBG90667.1 - 3.3e-10 40.5 0.0 5.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 GBG90667.1 - 0.016 14.6 8.3 0.012 15.0 6.3 1.8 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate SNARE_assoc PF09335.11 GBG90667.1 - 0.37 11.3 7.8 0.18 12.3 3.2 2.6 3 0 0 3 3 3 0 SNARE associated Golgi protein CCT PF06203.14 GBG90669.1 - 5.2e-17 61.6 16.0 1.1e-16 60.5 16.0 1.6 1 0 0 1 1 1 1 CCT motif Nop14 PF04147.12 GBG90669.1 - 0.00014 20.2 21.6 0.00014 20.2 21.6 2.2 2 0 0 2 2 2 2 Nop14-like family YL1 PF05764.13 GBG90669.1 - 0.00076 19.7 39.8 0.0011 19.1 21.9 3.0 3 0 0 3 3 3 2 YL1 nuclear protein Mpp10 PF04006.12 GBG90669.1 - 0.0015 17.1 16.7 0.0015 17.1 16.7 2.5 2 0 0 2 2 2 2 Mpp10 protein PPP4R2 PF09184.11 GBG90669.1 - 0.036 13.7 42.4 0.019 14.6 26.3 2.9 3 0 0 3 3 3 0 PPP4R2 Sigma70_ner PF04546.13 GBG90669.1 - 1 9.2 37.1 0.7 9.7 7.8 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 GBG90669.1 - 1.2 7.1 58.4 2 6.4 13.4 2.4 3 0 0 3 3 3 0 DNA polymerase phi CCT_2 PF09425.10 GBG90669.1 - 1.4 8.8 4.7 3.6 7.6 4.7 1.7 1 0 0 1 1 1 0 Divergent CCT motif NOA36 PF06524.12 GBG90669.1 - 1.7 7.9 51.0 3.4 6.9 31.3 2.6 2 0 0 2 2 2 0 NOA36 protein Roughex PF06020.11 GBG90669.1 - 6.8 5.7 25.1 0.78 8.8 14.2 2.5 2 0 0 2 2 2 0 Drosophila roughex protein DUF659 PF04937.15 GBG90670.1 - 2.5e-34 118.3 0.2 4.4e-34 117.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SAPS PF04499.15 GBG90670.1 - 0.14 11.0 1.2 0.21 10.3 1.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop53 PF07767.11 GBG90670.1 - 0.14 11.5 15.9 0.25 10.7 15.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GBG90670.1 - 1.4 7.1 19.3 3.5 5.7 19.5 1.5 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 GBG90670.1 - 2.1 7.7 17.8 3.8 6.8 17.8 1.3 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 GBG90670.1 - 3.9 5.9 16.7 6.3 5.3 16.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF659 PF04937.15 GBG90671.1 - 4.4e-10 39.6 0.1 8e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90671.1 - 3.4e-05 23.5 0.2 8.6e-05 22.3 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DPBB_1 PF03330.18 GBG90673.1 - 8.8e-15 54.8 1.3 2e-14 53.6 0.1 2.1 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GBG90673.1 - 2.3e-09 37.2 0.0 4.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Pollen allergen DUF5348 PF17295.2 GBG90673.1 - 0.2 11.6 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) Gly_rich PF12810.7 GBG90674.1 - 0.018 14.9 10.6 0.019 14.9 10.6 1.1 1 0 0 1 1 1 0 Glycine rich protein Apt1 PF10351.9 GBG90674.1 - 0.12 11.2 3.1 0.14 11.0 3.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 GBG90674.1 - 0.2 10.4 12.2 0.23 10.2 12.2 1.0 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 GBG90674.1 - 0.24 11.5 25.9 0.33 11.1 25.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2828 PF11443.8 GBG90674.1 - 0.98 7.4 10.5 1.2 7.1 10.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Rrn6 PF10214.9 GBG90674.1 - 2.2 6.7 6.3 2.4 6.5 6.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4407 PF14362.6 GBG90674.1 - 4.7 6.5 7.5 5.6 6.2 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 GBG90675.1 - 0.0011 17.8 8.5 0.0013 17.6 8.5 1.0 1 0 0 1 1 1 1 Presenilin Apt1 PF10351.9 GBG90675.1 - 0.13 11.1 3.1 0.14 11.0 3.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CAF1 PF04857.20 GBG90675.1 - 1.8 7.6 4.2 2.6 7.2 4.2 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease SDA1 PF05285.12 GBG90675.1 - 7.5 5.9 39.4 10 5.4 39.4 1.0 1 0 0 1 1 1 0 SDA1 RT_RNaseH_2 PF17919.1 GBG90678.1 - 4.4e-112 366.8 0.1 4.4e-33 113.3 0.1 5.7 5 0 0 5 5 5 5 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90678.1 - 5e-108 354.6 3.9 2.2e-30 105.0 0.1 5.7 5 0 0 5 5 5 5 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90678.1 - 1.8e-91 305.6 6.4 9e-29 100.6 0.1 4.9 4 0 0 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90678.1 - 4.6e-21 75.2 0.0 2.4e-13 50.3 0.0 3.2 2 0 0 2 2 2 2 Integrase core domain Retrotrans_gag PF03732.17 GBG90678.1 - 2.6e-11 43.7 3.9 0.0076 16.5 0.0 6.3 6 0 0 6 6 5 2 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG90678.1 - 6.8e-07 29.8 0.0 2.5e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG90678.1 - 1.1e-06 28.5 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG90678.1 - 6.1e-05 23.5 0.1 0.00027 21.5 0.0 2.3 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG90678.1 - 0.0033 17.5 0.1 1.3 9.1 0.0 2.9 2 0 0 2 2 2 1 Integrase zinc binding domain Nif11 PF07862.11 GBG90678.1 - 0.021 15.1 0.3 3.5 8.0 0.0 4.1 4 0 0 4 4 4 0 Nif11 domain Asp_protease PF09668.10 GBG90678.1 - 0.2 11.5 0.0 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF2730 PF10805.8 GBG90678.1 - 2.5 8.3 6.6 5.2 7.2 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF4187 PF13821.6 GBG90678.1 - 5.6 6.8 10.6 0.065 13.0 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) TTL PF03133.15 GBG90679.1 - 8.1e-80 268.1 0.2 1.2e-79 267.6 0.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GBG90679.1 - 5.5e-07 29.1 0.4 0.0059 15.9 0.0 3.6 3 2 1 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 GBG90679.1 - 0.0033 16.7 0.0 0.32 10.2 0.0 2.5 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp Ish1 PF10281.9 GBG90679.1 - 0.0097 16.2 0.0 0.041 14.2 0.0 2.2 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein DUF3824 PF12868.7 GBG90681.1 - 1.7 9.3 7.6 0.22 12.1 3.2 1.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Retrotrans_gag PF03732.17 GBG90682.1 - 0.00096 19.4 0.1 0.0067 16.7 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein CLZ PF16526.5 GBG90682.1 - 0.077 13.4 1.5 0.28 11.6 0.2 2.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 GBG90682.1 - 0.078 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 GBG90682.1 - 0.87 10.1 4.6 0.66 10.5 0.4 2.8 3 1 0 3 3 3 0 Cell division protein ZapB FUSC PF04632.12 GBG90682.1 - 1.2 7.6 3.5 1.8 7.0 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family OKR_DC_1_C PF03711.15 GBG90683.1 - 0.15 12.4 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain OKR_DC_1_C PF03711.15 GBG90684.1 - 0.21 11.9 0.0 0.31 11.3 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain Glyco_tranf_2_3 PF13641.6 GBG90685.1 - 2.4e-25 89.8 0.0 3.5e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG90685.1 - 7.1e-22 78.3 2.5 7.1e-22 78.3 2.5 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG90685.1 - 1.1e-21 77.4 0.0 1.6e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 GBG90685.1 - 1.8e-18 66.5 9.4 1.6e-08 33.6 0.1 3.1 1 1 2 3 3 3 3 Cellulose synthase Glyco_transf_21 PF13506.6 GBG90685.1 - 4.3e-15 55.6 0.0 7.1e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 GBG90685.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF659 PF04937.15 GBG90686.1 - 8.5e-19 67.9 0.1 1.6e-18 67.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90686.1 - 1.7e-08 34.1 0.1 3.8e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Glyco_tran_WbsX PF14307.6 GBG90686.1 - 0.019 14.4 0.9 0.036 13.5 0.9 1.4 1 0 0 1 1 1 0 Glycosyltransferase WbsX Tir_receptor_C PF07489.11 GBG90687.1 - 2.2 8.2 10.3 5.9 6.8 10.3 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Mucin PF01456.17 GBG90687.1 - 3.8 7.5 10.0 11 6.0 10.0 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Asp_protease_2 PF13650.6 GBG90689.1 - 0.0022 18.6 0.0 0.0042 17.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG90689.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Nop53 PF07767.11 GBG90690.1 - 4.6 6.5 30.5 6.6 6.0 30.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cwf_Cwc_15 PF04889.12 GBG90690.1 - 6.9 6.3 23.4 9.7 5.8 23.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG90690.1 - 7.3 4.7 28.9 9.6 4.3 28.9 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG90691.1 - 2.5e-30 105.6 0.1 4e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90691.1 - 3.6e-30 103.9 0.0 1.1e-15 57.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90691.1 - 1.9e-26 92.4 0.0 3.7e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LAP1C PF05609.12 GBG90692.1 - 1.1 8.2 9.3 1.5 7.8 9.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Myb_DNA-bind_4 PF13837.6 GBG90693.1 - 6.3e-10 39.3 2.1 1.4e-08 35.0 0.5 2.4 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG90693.1 - 0.048 14.0 0.3 0.79 10.1 0.1 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_M10 PF00413.24 GBG90694.1 - 5.4e-42 143.3 0.0 9e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 GBG90694.1 - 4.2e-11 42.9 0.0 2e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Putative peptidoglycan binding domain Peptidase_M54 PF07998.11 GBG90694.1 - 0.0082 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M54 Metallopep PF12044.8 GBG90694.1 - 0.027 13.1 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 GBG90694.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 GBG90694.1 - 0.069 12.8 0.0 1 8.9 0.1 2.1 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 GBG90694.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 GBG90694.1 - 0.17 10.8 0.0 0.17 10.8 0.0 2.2 2 0 0 2 2 2 0 Peptidase M66 MrpF_PhaF PF04066.13 GBG90694.1 - 0.88 10.0 3.6 1.3 9.5 1.6 2.1 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) RVT_1 PF00078.27 GBG90695.1 - 3.8e-26 92.0 0.0 5.8e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90695.1 - 5.7e-23 80.8 0.0 9e-23 80.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90695.1 - 7.1e-14 52.0 0.0 1.5e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Metallophos PF00149.28 GBG90696.1 - 1.5e-19 71.3 0.8 2.3e-19 70.7 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GBG90696.1 - 0.0031 17.7 0.0 0.056 13.6 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SPX PF03105.19 GBG90696.1 - 0.0076 16.2 2.1 0.0096 15.9 2.1 1.1 1 0 0 1 1 1 1 SPX domain Med15 PF09606.10 GBG90696.1 - 7.7 5.1 10.1 9.8 4.7 10.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PCEMA1 PF07418.11 GBG90697.1 - 4.7 6.7 14.9 5.9 6.3 14.9 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 PCEMA1 PF07418.11 GBG90698.1 - 4.7 6.7 14.9 5.9 6.3 14.9 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Myb_DNA-bind_4 PF13837.6 GBG90700.1 - 7.9e-06 26.2 0.2 1.2e-05 25.6 0.2 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 GBG90700.1 - 0.045 14.0 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 F-box-like PF12937.7 GBG90701.1 - 0.0085 16.0 0.3 0.0085 16.0 0.3 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 GBG90701.1 - 0.019 14.8 0.6 0.019 14.8 0.6 3.0 2 0 0 2 2 2 0 F-box domain TSC22 PF01166.18 GBG90702.1 - 0.0034 17.7 9.0 0.034 14.4 0.4 3.7 3 0 0 3 3 3 2 TSC-22/dip/bun family Radical_SAM PF04055.21 GBG90702.1 - 0.058 13.8 0.4 0.12 12.8 0.4 1.5 1 0 0 1 1 1 0 Radical SAM superfamily DUF4407 PF14362.6 GBG90702.1 - 1.5 8.1 16.0 0.076 12.4 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 GBG90702.1 - 3.9 7.0 13.7 0.57 9.7 0.5 2.7 2 1 1 3 3 3 0 fzo-like conserved region DDE_Tnp_4 PF13359.6 GBG90704.1 - 2.3e-32 111.9 0.0 8.6e-30 103.5 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90704.1 - 1.8e-15 57.1 0.0 2.8e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90704.1 - 0.012 15.3 0.0 1.9 8.0 0.0 2.7 2 1 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG90705.1 - 5.2e-06 26.7 1.2 5.2e-06 26.7 1.2 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Tim54 PF11711.8 GBG90705.1 - 0.025 13.4 0.5 0.051 12.4 0.5 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM154 PF15102.6 GBG90705.1 - 0.14 12.1 0.6 0.47 10.3 0.6 1.9 1 0 0 1 1 1 0 TMEM154 protein family RVT_1 PF00078.27 GBG90706.1 - 3.8e-29 101.8 0.1 5.8e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90706.1 - 1.2e-10 41.3 0.0 3.2e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG90706.1 - 0.049 14.3 0.0 0.12 13.0 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease Myb_DNA-bind_4 PF13837.6 GBG90709.1 - 2.8e-11 43.7 2.8 8.9e-10 38.8 0.5 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain UPF0184 PF03670.13 GBG90709.1 - 0.048 14.0 0.1 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) MADF_DNA_bdg PF10545.9 GBG90709.1 - 0.39 11.1 1.4 0.61 10.4 0.2 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 GBG90710.1 - 1.9e-08 34.5 1.0 7.7e-07 29.4 0.3 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain TPT PF03151.16 GBG90712.1 - 2.7e-15 56.5 10.6 3.1e-15 56.3 10.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GBG90712.1 - 0.0012 18.1 10.9 0.0016 17.7 10.9 1.2 1 0 0 1 1 1 1 UAA transporter family TMEM174 PF15029.6 GBG90712.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 174 Myb_DNA-bind_4 PF13837.6 GBG90713.1 - 5.7e-11 42.6 0.8 3.8e-09 36.8 0.1 2.4 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Topo_Zn_Ribbon PF08272.11 GBG90714.1 - 0.015 15.0 0.3 0.027 14.1 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG90714.1 - 0.049 13.7 1.1 0.084 13.0 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG90715.1 - 3.9e-14 52.5 0.0 6.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90715.1 - 1.4e-07 31.8 0.0 2.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Na_trans_assoc PF06512.13 GBG90715.1 - 0.41 10.9 18.2 0.58 10.4 18.2 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 GBG90715.1 - 1.4 8.3 30.2 1.6 8.1 30.2 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 GBG90715.1 - 2.1 7.8 23.0 2.8 7.4 23.0 1.2 1 0 0 1 1 1 0 PPP4R2 VIR_N PF15912.5 GBG90715.1 - 2.6 7.5 17.1 3.6 7.1 17.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Serinc PF03348.15 GBG90715.1 - 3.5 6.4 4.4 4.6 6.1 4.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.7 GBG90715.1 - 4.1 5.4 11.0 4.9 5.2 11.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_pol_Rpc4 PF05132.14 GBG90715.1 - 7.7 6.9 10.2 13 6.2 10.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 GBG90715.1 - 8.8 5.0 11.2 10 4.7 11.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 GBG90715.1 - 9.4 5.1 7.9 14 4.5 7.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mid2 PF04478.12 GBG90716.1 - 0.11 12.3 0.2 0.19 11.5 0.2 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor RT_RNaseH_2 PF17919.1 GBG90717.1 - 2.4e-24 85.3 0.0 8.2e-23 80.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90717.1 - 4.2e-23 81.6 0.3 2.1e-22 79.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG90717.1 - 3e-08 34.2 0.0 7.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG90717.1 - 1.4e-07 31.4 0.0 3.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG90717.1 - 2e-06 28.2 0.0 6.2e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG90717.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG90717.1 - 0.0021 18.3 0.0 0.007 16.6 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG90717.1 - 0.0047 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain 4HBT_3 PF13622.6 GBG90717.1 - 0.011 16.0 0.1 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Thioesterase-like superfamily Mid2 PF04478.12 GBG90718.1 - 0.21 11.4 1.2 0.72 9.7 0.0 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor RT_RNaseH_2 PF17919.1 GBG90719.1 - 2.9e-27 94.6 0.0 8.3e-27 93.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90719.1 - 3.7e-23 81.8 0.2 1.3e-22 80.0 0.2 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TTc_toxin_rep PF18807.1 GBG90720.1 - 0.1 12.4 0.4 13 5.7 0.0 2.7 3 0 0 3 3 3 0 Tripartite Tc toxins repeat zf-C2H2_3 PF13878.6 GBG90722.1 - 5.5e-14 51.7 0.1 1.1e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zf-C2H2_3 PF13878.6 GBG90723.1 - 5e-14 51.8 0.1 1.1e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DUF659 PF04937.15 GBG90725.1 - 2.9e-30 105.1 0.0 3.9e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PIG-S PF10510.9 GBG90726.1 - 1.4 7.7 9.7 2.1 7.1 9.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein PAT1 PF09770.9 GBG90726.1 - 8.7 4.5 21.2 11 4.2 21.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TraB PF01963.17 GBG90727.1 - 1.8e-26 93.6 0.0 2.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 TraB family GREB1 PF15782.5 GBG90727.1 - 0.39 7.8 0.6 0.6 7.2 0.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer THUMP PF02926.17 GBG90728.1 - 0.0061 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 THUMP domain THUMP PF02926.17 GBG90729.1 - 0.0049 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 THUMP domain THOC7 PF05615.13 GBG90730.1 - 4.5e-22 78.8 8.2 7.1e-22 78.1 8.2 1.3 1 0 0 1 1 1 1 Tho complex subunit 7 FIBP PF05427.11 GBG90730.1 - 0.062 12.6 0.2 0.094 12.0 0.2 1.2 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) LysM PF01476.20 GBG90731.1 - 0.00026 21.0 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 LysM domain Peptidase_M20 PF01546.28 GBG90733.1 - 6.2e-23 81.6 0.0 8.9e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GBG90733.1 - 1.4e-13 50.7 0.0 3.2e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GBG90733.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 EzrA PF06160.12 GBG90734.1 - 0.011 13.9 10.9 0.14 10.3 1.1 3.2 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Bcr-Abl_Oligo PF09036.10 GBG90734.1 - 0.04 13.9 1.0 9.7 6.3 0.5 3.0 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF2730 PF10805.8 GBG90734.1 - 0.16 12.1 3.4 14 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) ING PF12998.7 GBG90734.1 - 0.68 10.5 7.7 0.44 11.2 1.2 3.1 3 2 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF5595 PF18077.1 GBG90734.1 - 1 9.5 6.7 4.2 7.5 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) CAP_N PF01213.19 GBG90734.1 - 1.2 8.6 9.0 79 2.6 9.0 2.2 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Laminin_II PF06009.12 GBG90734.1 - 1.2 9.1 10.5 5.9 6.9 0.8 3.8 3 2 0 3 3 3 0 Laminin Domain II DivIC PF04977.15 GBG90734.1 - 2.1 8.2 0.0 2.1 8.2 0.0 4.0 2 1 2 5 5 5 0 Septum formation initiator V_ATPase_I PF01496.19 GBG90734.1 - 3.4 5.5 8.6 3 5.7 5.6 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family WSD PF15613.6 GBG90734.1 - 4.6 7.8 8.5 14 6.3 8.0 2.2 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif FlaC_arch PF05377.11 GBG90734.1 - 6.3 7.3 8.8 0.51 10.8 0.3 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2939 PF11159.8 GBG90734.1 - 7.2 7.1 7.3 4.5 7.7 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) ING PF12998.7 GBG90735.1 - 1.3e-19 70.6 0.0 1.8e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GBG90735.1 - 4.7e-08 32.8 6.8 7.7e-08 32.1 6.8 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GBG90735.1 - 0.022 15.0 1.1 0.054 13.8 1.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 GBG90735.1 - 0.022 14.3 1.4 0.036 13.6 1.4 1.4 1 0 0 1 1 1 0 PHD-finger Aminotran_5 PF00266.19 GBG90737.1 - 1.8e-28 99.6 0.0 4.2e-18 65.5 0.0 2.3 1 1 1 2 2 2 2 Aminotransferase class-V DUF1664 PF07889.12 GBG90737.1 - 0.058 13.4 5.2 0.16 12.0 5.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5069 PF16798.5 GBG90737.1 - 0.7 10.1 4.5 0.43 10.8 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) PEP-utilisers_N PF05524.13 GBG90737.1 - 4.2 7.6 13.0 0.2 11.8 5.7 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Fasciclin PF02469.22 GBG90738.1 - 7.6e-06 26.2 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain RT_RNaseH PF17917.1 GBG90739.1 - 4.7e-22 78.3 0.1 1e-21 77.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90739.1 - 9.1e-22 77.0 0.0 2.2e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90739.1 - 2.7e-15 56.2 0.5 5.5e-15 55.2 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90739.1 - 3.6e-09 36.8 0.0 1.1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG90739.1 - 1.3e-08 34.7 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG90739.1 - 4.2e-07 29.7 0.1 0.018 14.5 0.0 2.8 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG90739.1 - 2e-06 28.4 0.0 3.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90739.1 - 2.3e-05 24.9 0.0 4.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG90739.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG90740.1 - 3.1e-18 66.1 0.0 4.5e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Integrase_H2C2 PF17921.1 GBG90741.1 - 2.6e-12 46.7 0.6 7.1e-12 45.2 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90741.1 - 2.9e-12 46.8 0.4 7.8e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG90741.1 - 2.3e-08 34.5 0.0 6.3e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG90741.1 - 1.5e-07 31.2 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG90741.1 - 2.2e-05 25.0 0.0 6.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG90741.1 - 0.0019 18.0 0.2 0.0039 17.0 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG90741.1 - 0.0052 17.0 0.1 0.39 11.0 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG90741.1 - 0.0056 16.9 0.7 0.014 15.6 0.7 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVP PF00077.20 GBG90741.1 - 0.17 12.2 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease CCP_MauG PF03150.14 GBG90743.1 - 0.091 13.4 1.1 0.19 12.4 1.1 1.5 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Histone_HNS PF00816.21 GBG90743.1 - 0.13 13.1 6.4 0.56 11.1 6.2 2.1 2 0 0 2 2 2 0 H-NS histone family DUF2781 PF10914.8 GBG90743.1 - 0.13 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) SNAD4 PF18750.1 GBG90743.1 - 1 9.5 4.9 0.46 10.6 2.0 1.9 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 RNA_pol_Rpc4 PF05132.14 GBG90744.1 - 0.16 12.4 0.7 2.7 8.4 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Zip PF02535.22 GBG90744.1 - 2.7 7.1 5.2 23 4.1 4.2 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Nop14 PF04147.12 GBG90744.1 - 5.7 5.0 18.6 8.6 4.4 18.6 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG90744.1 - 7.7 4.5 21.0 11 4.0 21.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-CCHC_3 PF13917.6 GBG90745.1 - 0.025 14.6 2.2 0.054 13.5 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle FtsK_4TM PF13491.6 GBG90745.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE RVT_1 PF00078.27 GBG90746.1 - 2.6e-28 99.1 0.2 5.1e-28 98.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90746.1 - 9.4e-27 93.0 0.1 1.8e-26 92.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90746.1 - 6.3e-25 87.5 0.1 1.3e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90746.1 - 1e-18 67.2 0.3 2.3e-18 66.0 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90746.1 - 7.4e-06 26.2 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90746.1 - 0.0073 16.5 0.1 0.086 13.1 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger Myb_DNA-bind_4 PF13837.6 GBG90747.1 - 9.8e-07 29.1 2.9 1.5e-06 28.5 2.9 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG90747.1 - 0.0021 18.2 0.7 0.0039 17.4 0.7 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG90747.1 - 0.0085 16.4 0.3 0.015 15.6 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG90747.1 - 0.0089 16.1 0.6 0.015 15.4 0.6 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HSP70 PF00012.20 GBG90749.1 - 1.2e-160 535.7 2.2 2.1e-151 505.1 0.0 2.9 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 GBG90749.1 - 8.2e-08 31.4 0.0 5.5e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein CCDC-167 PF15188.6 GBG90749.1 - 0.0063 16.8 4.7 0.0063 16.8 4.7 2.2 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 FtsA PF14450.6 GBG90749.1 - 0.0073 16.7 0.5 12 6.4 0.0 3.5 3 0 0 3 3 3 1 Cell division protein FtsA DDR PF08841.10 GBG90749.1 - 0.024 13.6 1.0 0.083 11.9 0.3 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF2457 PF10446.9 GBG90749.1 - 0.45 9.6 12.0 1 8.4 12.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2052 PF09747.9 GBG90749.1 - 4.5 7.4 16.4 0.1 12.7 6.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.14 GBG90749.1 - 8.7 6.1 9.2 18 5.0 9.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein UPF0242 PF06785.11 GBG90750.1 - 2.5 8.1 20.1 5.3 7.1 20.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UCMA PF17085.5 GBG90751.1 - 0.031 14.3 7.0 0.075 13.1 7.0 1.7 1 0 0 1 1 1 0 Unique cartilage matrix associated protein HALZ PF02183.18 GBG90753.1 - 0.23 11.7 3.4 0.42 10.9 2.1 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GBG90753.1 - 0.44 10.7 9.9 0.68 10.1 3.5 2.7 2 1 0 2 2 2 0 bZIP transcription factor Bap31_Bap29_C PF18035.1 GBG90753.1 - 0.64 10.1 6.4 0.12 12.4 1.1 2.4 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Cnn_1N PF07989.11 GBG90753.1 - 0.9 9.7 6.4 0.24 11.6 1.9 2.1 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 GBG90753.1 - 1.8 8.4 5.8 0.52 10.1 1.8 2.2 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 GBG90753.1 - 6.3 7.3 8.7 0.56 10.7 3.2 2.2 2 1 0 2 2 2 0 Cell division protein ZapB Myb_DNA-bind_4 PF13837.6 GBG90755.1 - 7.3e-06 26.3 4.9 1.9e-05 24.9 3.1 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG90755.1 - 0.093 13.1 1.3 3.2 8.2 0.9 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF659 PF04937.15 GBG90756.1 - 2.7e-12 46.8 0.0 5.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90756.1 - 0.00039 20.2 0.0 0.00096 18.9 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG90757.1 - 5.8e-39 133.9 0.0 1.2e-38 132.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG90757.1 - 0.00029 20.5 0.2 0.00075 19.1 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ADK PF00406.22 GBG90758.1 - 1.4e-15 57.7 0.0 1.5e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GBG90758.1 - 1.2e-10 42.0 0.1 1.2e-10 42.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 GBG90758.1 - 0.013 15.2 0.1 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_33 PF13671.6 GBG90758.1 - 0.044 14.0 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rhodanese PF00581.20 GBG90759.1 - 8.9e-08 32.6 0.0 3.9e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Rhodanese-like domain PARM PF17061.5 GBG90759.1 - 0.1 12.7 5.8 0.14 12.2 5.8 1.1 1 0 0 1 1 1 0 PARM RVT_1 PF00078.27 GBG90761.1 - 1.8e-19 70.1 0.1 7e-18 64.9 0.0 2.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90761.1 - 7.7e-17 61.2 0.0 1.7e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90761.1 - 2.4e-15 56.7 0.0 1e-14 54.8 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG90761.1 - 8.7e-05 22.8 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1564 PF07600.11 GBG90761.1 - 0.035 13.8 0.0 0.098 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) rve_3 PF13683.6 GBG90761.1 - 0.087 12.6 0.2 1.8 8.4 0.0 3.0 3 0 0 3 3 3 0 Integrase core domain HTH_5 PF01022.20 GBG90761.1 - 0.17 11.8 0.4 2.9 7.8 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Integrase_H2C2 PF17921.1 GBG90762.1 - 8.6e-15 54.6 0.3 2.5e-14 53.1 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90762.1 - 1.4e-12 47.9 0.0 2.8e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90762.1 - 2e-09 37.6 0.0 4.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG90762.1 - 6.7e-09 35.6 0.1 1.1e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90762.1 - 4e-07 30.0 0.0 7.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG90762.1 - 0.00025 20.9 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG90762.1 - 0.0078 16.4 0.2 0.022 15.0 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF659 PF04937.15 GBG90763.1 - 1.1e-32 113.0 0.1 1.8e-32 112.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2120 PF09893.9 GBG90764.1 - 1.1 9.4 8.8 0.098 12.8 3.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF469 PF04320.14 GBG90764.1 - 1.7 9.5 5.9 0.24 12.2 0.9 2.2 2 1 0 2 2 2 0 Protein with unknown function (DUF469) DUF702 PF05142.12 GBG90764.1 - 2.8 8.4 6.5 0.78 10.2 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF702) DDE_Tnp_4 PF13359.6 GBG90765.1 - 7.8e-31 106.9 0.0 1.3e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90765.1 - 1.6e-15 57.2 0.0 2.4e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90765.1 - 8.7e-05 22.3 0.2 0.049 13.3 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain DUF1645 PF07816.11 GBG90766.1 - 0.19 12.3 2.0 0.18 12.4 0.2 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1645) RVT_1 PF00078.27 GBG90767.1 - 4.8e-18 65.5 0.0 7.8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GATA PF00320.27 GBG90767.1 - 8.9e-17 60.4 3.2 2.6e-16 58.9 3.2 1.9 1 0 0 1 1 1 1 GATA zinc finger RT_RNaseH_2 PF17919.1 GBG90767.1 - 2.1e-06 27.7 0.0 7.1e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SlyX PF04102.12 GBG90767.1 - 0.049 14.3 0.2 0.049 14.3 0.2 3.4 3 0 0 3 3 3 0 SlyX DNA_pol_phi PF04931.13 GBG90767.1 - 5.8 4.9 31.7 13 3.8 31.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi FUSC PF04632.12 GBG90767.1 - 7.7 4.9 14.9 17 3.8 14.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF659 PF04937.15 GBG90768.1 - 7.7e-35 120.0 0.1 1.4e-34 119.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG90768.1 - 4e-05 23.5 1.4 0.00011 22.1 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG90768.1 - 0.022 14.6 2.5 0.045 13.6 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Toprim_N PF08275.11 GBG90769.1 - 7.9e-07 29.2 5.2 25 4.9 0.0 8.1 4 1 5 9 9 9 2 DNA primase catalytic core, N-terminal domain PapC_C PF13953.6 GBG90769.1 - 7.3e-05 22.5 31.2 2 8.3 0.3 8.8 3 2 8 11 11 11 7 PapC C-terminal domain DUF5419 PF17441.2 GBG90769.1 - 0.092 12.9 1.1 10 6.3 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5419) RTA1 PF04479.13 GBG90769.1 - 0.31 10.6 16.9 26 4.3 0.1 7.8 4 1 6 10 10 10 0 RTA1 like protein SH3_19 PF18597.1 GBG90769.1 - 0.45 10.4 35.6 21 5.1 0.2 9.8 10 0 0 10 10 10 0 Myosin X N-terminal SH3 domain FBA_3 PF08268.12 GBG90769.1 - 2 8.4 18.3 0.26 11.2 0.7 4.7 2 1 2 5 5 5 0 F-box associated domain BUD22 PF09073.10 GBG90770.1 - 0.0027 17.1 23.4 0.0039 16.6 23.4 1.2 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 GBG90770.1 - 0.029 12.7 16.4 0.037 12.3 16.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG90770.1 - 0.03 14.1 20.4 0.036 13.8 20.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG90770.1 - 0.079 12.4 23.5 0.088 12.2 23.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG90770.1 - 0.081 11.1 25.2 0.089 11.0 25.2 1.0 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 GBG90770.1 - 0.9 9.0 12.4 1.1 8.7 12.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NOA36 PF06524.12 GBG90770.1 - 1.5 8.1 15.0 2.1 7.6 15.0 1.3 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 GBG90770.1 - 1.8 7.3 11.0 1.9 7.1 11.0 1.1 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 GBG90770.1 - 2.8 6.9 11.0 3.3 6.7 11.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC27 PF09507.10 GBG90770.1 - 4.3 6.6 21.8 6.3 6.1 21.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vfa1 PF08432.10 GBG90770.1 - 5.7 7.2 12.7 9.1 6.6 12.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 GBG90770.1 - 6.5 5.9 4.9 7.8 5.6 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 GBG90770.1 - 8.4 6.1 17.3 14 5.4 17.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 GBG90771.1 - 0.15 11.6 13.2 0.092 12.3 10.8 1.8 2 0 0 2 2 2 0 PPP4R2 Nop14 PF04147.12 GBG90771.1 - 0.33 9.1 17.8 0.48 8.6 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG90771.1 - 1.4 8.2 14.4 2.1 7.6 14.4 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG90771.1 - 2.4 7.5 17.6 3.9 6.8 17.6 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG90771.1 - 2.7 6.2 12.4 3.9 5.6 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 GBG90771.1 - 8 6.1 8.1 19 4.9 8.1 1.7 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 GBG90771.1 - 8 4.4 22.3 11 3.9 22.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi USP8_interact PF08941.10 GBG90772.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 USP8 interacting RT_RNaseH_2 PF17919.1 GBG90775.1 - 9.9e-26 89.7 0.0 3.2e-25 88.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90775.1 - 7.5e-23 80.8 0.0 2e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG90775.1 - 4.4e-08 33.7 0.0 1.2e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90775.1 - 3.2e-07 30.8 0.0 9.9e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG90775.1 - 4.1e-06 26.6 0.0 8.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG90775.1 - 6e-06 25.9 0.4 1e-05 25.2 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG90775.1 - 0.00035 20.4 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG90778.1 - 2.4e-16 59.9 0.0 4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_5 PF13873.6 GBG90779.1 - 6.7e-05 22.9 1.1 0.00015 21.7 1.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG90779.1 - 0.00028 21.2 0.9 0.00028 21.2 0.9 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG90780.1 - 6.5e-31 107.1 0.0 8.8e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90780.1 - 1.6e-12 47.5 0.0 3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90780.1 - 0.0031 17.2 0.0 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain Pkinase PF00069.25 GBG90781.1 - 1.8e-35 122.6 0.0 1.8e-35 122.6 0.0 1.9 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG90781.1 - 4.4e-33 114.7 0.0 1.4e-24 86.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2052 PF09747.9 GBG90781.1 - 0.00012 22.3 30.6 0.013 15.6 17.3 2.6 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) APH PF01636.23 GBG90781.1 - 0.00034 20.6 0.0 0.0013 18.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG90781.1 - 0.0005 19.0 9.7 0.0047 15.8 0.0 2.9 3 0 0 3 3 3 1 Fungal protein kinase gag-asp_proteas PF13975.6 GBG90781.1 - 0.0035 17.9 0.0 0.088 13.4 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DDHD PF02862.17 GBG90781.1 - 0.0064 16.7 11.5 0.95 9.6 0.1 2.4 2 0 0 2 2 2 2 DDHD domain Coilin_N PF15862.5 GBG90781.1 - 0.011 15.5 42.1 0.057 13.2 28.1 2.5 2 0 0 2 2 2 0 Coilin N-terminus SpoIIIAH PF12685.7 GBG90781.1 - 0.012 15.4 22.6 0.21 11.4 1.3 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF1758 PF05585.12 GBG90781.1 - 0.04 13.7 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) CDC45 PF02724.14 GBG90781.1 - 0.12 10.6 39.9 0.12 10.6 23.4 2.2 2 0 0 2 2 2 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 GBG90781.1 - 0.14 12.6 27.4 0.58 10.6 1.8 2.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 Zip PF02535.22 GBG90781.1 - 0.21 10.8 17.1 0.48 9.6 0.2 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter SpoIIP PF07454.11 GBG90781.1 - 0.6 9.5 31.2 0.11 11.9 2.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF5308 PF17233.2 GBG90781.1 - 0.75 10.0 7.5 38 4.4 5.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Adaptin_binding PF10199.9 GBG90781.1 - 0.79 10.3 27.8 0.48 11.0 2.5 3.1 3 0 0 3 3 2 0 Alpha and gamma adaptin binding protein p34 AAR2 PF05282.11 GBG90781.1 - 0.92 8.8 16.9 0.15 11.5 6.6 2.3 2 0 0 2 2 2 0 AAR2 protein Ribosomal_60s PF00428.19 GBG90781.1 - 1.2 9.7 0.0 1.2 9.7 0.0 6.8 6 2 0 6 6 2 0 60s Acidic ribosomal protein Insulin_TMD PF17870.1 GBG90781.1 - 1.3 9.2 4.0 1 9.5 1.6 2.1 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment GAGA_bind PF06217.12 GBG90781.1 - 1.4 9.1 23.3 0.72 10.1 16.1 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Mpp10 PF04006.12 GBG90781.1 - 1.5 7.2 53.4 0.19 10.1 28.4 2.1 2 0 0 2 2 2 0 Mpp10 protein Connexin PF00029.19 GBG90781.1 - 2.2 8.0 26.6 0.49 10.1 0.3 2.4 2 0 0 2 2 2 0 Connexin Paf1 PF03985.13 GBG90781.1 - 4.3 6.2 55.0 0.11 11.5 27.2 2.2 2 0 0 2 2 2 0 Paf1 SAPS PF04499.15 GBG90781.1 - 5.1 5.8 21.4 1.4 7.6 1.3 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 GBG90781.1 - 6.4 6.5 49.6 1.4 8.7 29.6 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 YL1 PF05764.13 GBG90781.1 - 6.4 6.8 54.6 0.011 15.8 29.0 2.9 3 0 0 3 3 2 0 YL1 nuclear protein Nop14 PF04147.12 GBG90781.1 - 7 4.7 44.5 2.7 6.1 24.4 2.2 2 0 0 2 2 2 0 Nop14-like family DDE_Tnp_4 PF13359.6 GBG90782.1 - 2.2e-26 92.4 0.0 4.2e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90782.1 - 1.5e-12 47.5 0.0 3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90782.1 - 2.4e-05 24.1 0.8 0.014 15.1 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain Pkinase_Tyr PF07714.17 GBG90784.1 - 3.2e-32 111.8 0.0 4.1e-31 108.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 GBG90784.1 - 8.2e-31 107.2 0.1 1.4e-30 106.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GBG90784.1 - 1.1e-30 106.9 0.0 2e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG90784.1 - 1.1e-16 60.7 0.0 4.6e-14 52.3 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Peptidase_C48 PF02902.19 GBG90784.1 - 7.1e-10 39.1 0.0 1.7e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RT_RNaseH PF17917.1 GBG90784.1 - 4.6e-06 26.9 0.0 1.3e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APH PF01636.23 GBG90784.1 - 4.6e-05 23.4 1.9 0.00012 22.1 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family AT_hook PF02178.19 GBG90786.1 - 0.012 15.4 5.7 0.033 14.0 5.7 1.8 1 0 0 1 1 1 0 AT hook motif HYLS1_C PF15311.6 GBG90786.1 - 0.038 14.7 0.4 0.14 13.0 0.0 2.0 1 1 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus DUF4692 PF15763.5 GBG90786.1 - 4.7 7.7 6.6 7.8 6.9 6.4 1.4 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SDA1 PF05285.12 GBG90787.1 - 0.018 14.5 26.0 0.021 14.2 26.0 1.1 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 GBG90787.1 - 0.083 12.0 15.2 0.11 11.6 15.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG90787.1 - 0.093 10.9 26.2 0.11 10.7 26.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG90787.1 - 0.12 10.7 17.5 0.15 10.3 17.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG90787.1 - 0.38 10.3 11.1 0.49 9.9 11.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 GBG90787.1 - 0.4 9.4 9.7 0.45 9.2 9.7 1.1 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GBG90787.1 - 0.7 9.2 26.2 0.96 8.7 26.2 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GBG90787.1 - 1.6 7.4 9.7 1.9 7.2 9.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 GBG90787.1 - 1.7 7.8 9.0 2.2 7.4 9.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CCSAP PF15748.5 GBG90787.1 - 2.2 8.4 14.0 3.4 7.8 14.0 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TFIIF_alpha PF05793.12 GBG90787.1 - 3.2 6.2 24.3 5.2 5.5 24.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 GBG90787.1 - 6.8 5.4 6.8 8.5 5.1 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF928 PF06051.12 GBG90789.1 - 0.047 13.6 1.8 0.47 10.3 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) RVT_1 PF00078.27 GBG90790.1 - 1.9e-29 102.8 0.1 3.5e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90790.1 - 2.5e-23 82.0 0.0 4.8e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90790.1 - 2.9e-22 78.9 0.0 5.1e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90790.1 - 3.5e-18 65.5 0.5 7.3e-18 64.4 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90790.1 - 9.9e-09 35.4 0.0 2.7e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Serglycin PF04360.12 GBG90791.1 - 0.063 13.2 2.0 0.083 12.8 2.0 1.3 1 0 0 1 1 1 0 Serglycin Romo1 PF10247.9 GBG90791.1 - 0.17 12.2 1.0 0.17 12.2 1.0 2.7 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 GBG90791.1 - 1.2 9.5 10.5 0.52 10.7 0.3 2.4 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family KRTAP PF11759.8 GBG90791.1 - 3.5 8.2 20.7 5.4 7.6 20.7 1.4 1 1 0 1 1 1 0 Keratin-associated matrix Nop14 PF04147.12 GBG90792.1 - 0.07 11.3 20.5 0.075 11.2 20.5 1.0 1 0 0 1 1 1 0 Nop14-like family TFB6 PF17110.5 GBG90792.1 - 0.11 12.3 8.1 0.12 12.1 8.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 GBG90792.1 - 0.68 8.2 17.5 0.78 8.0 17.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG90792.1 - 1.9 7.8 22.6 2.1 7.7 22.6 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GBG90792.1 - 2.2 6.3 35.3 2.6 6.1 35.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 GBG90792.1 - 8.6 5.6 20.8 8.9 5.5 20.8 1.0 1 0 0 1 1 1 0 BUD22 ATG16 PF08614.11 GBG90793.1 - 0.069 13.4 0.5 0.46 10.7 0.1 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 GBG90793.1 - 0.22 11.3 0.0 0.5 10.2 0.0 1.5 1 0 0 1 1 1 0 Septum formation initiator RVT_1 PF00078.27 GBG90794.1 - 4.3e-22 78.7 1.2 9.6e-22 77.6 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90794.1 - 2e-13 50.2 0.0 8.1e-13 48.3 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90794.1 - 9.8e-12 45.1 0.0 4.1e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase TMF_DNA_bd PF12329.8 GBG90794.1 - 0.061 13.3 1.2 0.15 12.1 1.2 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.8 GBG90794.1 - 0.071 13.2 0.4 0.22 11.6 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Integrin_b_cyt PF08725.11 GBG90794.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Retrotrans_gag PF03732.17 GBG90794.1 - 0.19 12.0 1.5 2.3 8.6 0.0 3.2 3 0 0 3 3 3 0 Retrotransposon gag protein DUF1664 PF07889.12 GBG90794.1 - 0.33 11.0 3.7 0.54 10.3 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GBG90794.1 - 1.4 9.0 6.5 0.7 9.9 3.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 GBG90794.1 - 2.1 9.0 11.6 0.29 11.8 4.1 2.9 1 1 0 2 2 2 0 SlyX TolA_bind_tri PF16331.5 GBG90794.1 - 2.7 8.1 10.2 2.8 8.1 7.8 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation RVT_1 PF00078.27 GBG90795.1 - 4e-27 95.2 0.0 8.3e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90795.1 - 1.1e-16 60.7 0.4 2.3e-16 59.6 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG90795.1 - 4.6e-16 59.2 0.0 8.7e-07 29.5 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG90795.1 - 3.2e-15 56.4 0.0 1.5e-06 28.7 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG90795.1 - 6.6e-12 45.3 0.0 2.1e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.11 GBG90795.1 - 2e-11 43.8 0.0 6.9e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG90795.1 - 4e-07 30.2 3.2 0.0042 17.3 0.0 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein DUF4187 PF13821.6 GBG90795.1 - 0.014 15.2 0.9 0.047 13.5 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-H2C2 PF09337.10 GBG90795.1 - 0.029 14.6 0.3 0.07 13.4 0.3 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve PF00665.26 GBG90795.1 - 0.07 13.3 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain SMP_LBD PF17047.5 GBG90796.1 - 0.17 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain RT_RNaseH_2 PF17919.1 GBG90797.1 - 2.1e-23 82.3 0.0 5.3e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90797.1 - 3.5e-21 75.5 0.0 7.9e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90797.1 - 8.7e-21 74.5 0.0 1.9e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG90797.1 - 2.5e-05 24.5 1.8 0.01 16.1 0.0 3.6 3 0 0 3 3 3 2 Retrotransposon gag protein CLZ PF16526.5 GBG90797.1 - 2.5 8.5 8.3 0.11 12.8 0.7 2.8 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CLZ PF16526.5 GBG90798.1 - 0.029 14.7 0.7 0.029 14.7 0.7 3.2 3 2 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RT_RNaseH_2 PF17919.1 GBG90800.1 - 1.1e-24 86.3 0.0 2.6e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90800.1 - 5.9e-22 77.9 0.0 2.5e-21 75.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90800.1 - 3.8e-11 43.2 0.0 8.4e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG90800.1 - 0.0038 17.0 0.0 0.012 15.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG90800.1 - 0.022 15.0 0.1 0.096 13.0 0.1 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein Uds1 PF15456.6 GBG90800.1 - 0.11 12.6 2.4 0.94 9.6 0.6 2.7 2 0 0 2 2 2 0 Up-regulated During Septation SbmA_BacA PF05992.12 GBG90801.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 SbmA/BacA-like family Nop14 PF04147.12 GBG90803.1 - 0.051 11.8 7.2 0.056 11.7 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG90803.1 - 6 5.0 7.8 6.5 4.9 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG90806.1 - 1.3e-18 67.3 0.0 2.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SlyX PF04102.12 GBG90806.1 - 0.039 14.6 0.6 0.68 10.6 0.0 2.8 2 0 0 2 2 2 0 SlyX Peptidase_C48 PF02902.19 GBG90809.1 - 3.3e-22 79.4 0.0 5.3e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-CCHC PF00098.23 GBG90811.1 - 1.4 9.1 3.2 2.3 8.5 3.2 1.3 1 0 0 1 1 1 0 Zinc knuckle HSP70 PF00012.20 GBG90812.1 - 2.9e-130 435.3 1.0 3e-81 273.4 0.8 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG90812.1 - 4.8e-13 48.6 0.9 8.4e-13 47.8 0.4 1.6 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 GBG90812.1 - 0.00056 19.0 0.6 0.062 12.3 0.2 2.2 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain DNA_primase_lrg PF04104.14 GBG90812.1 - 0.0065 15.9 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit StbA PF06406.11 GBG90812.1 - 0.015 14.6 0.4 0.031 13.5 0.4 1.7 1 1 0 1 1 1 0 StbA protein BcrAD_BadFG PF01869.20 GBG90812.1 - 0.021 14.3 0.2 2.2 7.7 0.1 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family YmaF PF12788.7 GBG90813.1 - 1.1 9.8 6.4 0.16 12.5 1.8 1.8 2 0 0 2 2 2 0 YmaF family DUF572 PF04502.13 GBG90815.1 - 0.092 12.3 13.6 0.12 11.9 13.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) EIIC-GAT PF03611.14 GBG90815.1 - 0.25 10.4 3.2 0.32 10.1 3.2 1.1 1 0 0 1 1 1 0 PTS system sugar-specific permease component EIIC-GAT PF03611.14 GBG90816.1 - 0.16 11.0 3.3 0.2 10.7 3.3 1.1 1 0 0 1 1 1 0 PTS system sugar-specific permease component HhH-GPD PF00730.25 GBG90817.1 - 1.2e-06 28.9 0.0 3.8e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NARP1 PF12569.8 GBG90818.1 - 3.1e-190 633.5 17.4 9.2e-131 437.3 13.1 3.0 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 GBG90818.1 - 1.9e-17 61.9 13.1 0.0017 18.3 0.0 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 GBG90818.1 - 6.8e-14 51.4 27.1 0.0062 17.3 0.1 9.8 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 GBG90818.1 - 9.8e-11 40.9 1.9 0.0012 18.8 0.0 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG90818.1 - 1.9e-10 40.1 11.4 0.0016 18.2 0.0 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GBG90818.1 - 1.1e-09 37.7 3.6 0.014 15.5 0.1 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GBG90818.1 - 1.8e-09 38.1 38.7 0.00038 21.0 0.8 8.5 10 0 0 10 10 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 GBG90818.1 - 7.9e-09 35.1 1.4 0.00048 19.8 0.0 4.8 6 0 0 6 6 6 2 TPR repeat TPR_19 PF14559.6 GBG90818.1 - 3.7e-06 27.4 16.1 0.6 10.7 0.0 6.8 5 2 1 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 GBG90818.1 - 7.3e-06 26.0 0.1 4.2 8.0 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GBG90818.1 - 6.3e-05 23.1 6.5 3.3 8.0 0.2 4.7 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 GBG90818.1 - 0.0001 22.4 16.7 0.067 13.4 0.6 6.6 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 GBG90818.1 - 0.0001 22.7 15.6 12 6.7 0.0 7.4 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG90818.1 - 0.00057 20.1 12.3 0.43 10.9 0.3 6.3 5 2 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GBG90818.1 - 0.0017 18.4 4.5 1.9 8.6 0.1 4.7 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat BAF1_ABF1 PF04684.13 GBG90818.1 - 0.0034 16.5 0.1 1 8.4 0.7 2.4 2 1 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor Myc_N PF01056.18 GBG90818.1 - 0.75 9.6 6.7 1.2 9.0 1.9 2.4 2 0 0 2 2 2 0 Myc amino-terminal region PBP1_TM PF14812.6 GBG90818.1 - 3.5 8.1 11.0 0.4 11.1 4.8 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Utp14 PF04615.13 GBG90818.1 - 4 5.9 15.5 1.9 6.9 5.3 2.1 2 0 0 2 2 2 0 Utp14 protein GEMIN8 PF15348.6 GBG90818.1 - 4.9 7.4 8.7 0.72 10.1 0.9 2.3 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 TPR_10 PF13374.6 GBG90818.1 - 6.4 6.8 9.7 1e+02 3.0 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DnaJ_C PF01556.18 GBG90819.1 - 1.2e-37 129.3 0.0 1.6e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 GBG90819.1 - 7.9e-12 45.4 14.7 7.9e-12 45.4 14.7 2.3 2 0 0 2 2 2 1 DnaJ central domain DnaJ PF00226.31 GBG90819.1 - 1.3e-05 25.3 0.3 2.1e-05 24.5 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Chorion_3 PF05387.11 GBG90819.1 - 0.17 11.5 1.7 0.27 10.9 1.7 1.2 1 0 0 1 1 1 0 Chorion family 3 Anti-TRAP PF15777.5 GBG90819.1 - 2.7 8.0 18.3 0.22 11.5 2.4 3.7 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein RPOL_N PF14700.6 GBG90820.1 - 0.019 14.4 4.9 0.038 13.4 4.9 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF3492 PF11997.8 GBG90820.1 - 0.12 12.1 0.6 0.19 11.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) RE_TdeIII PF09520.10 GBG90820.1 - 0.12 12.0 6.3 0.17 11.5 5.4 1.6 1 1 0 1 1 1 0 Type II restriction endonuclease, TdeIII DDRGK PF09756.9 GBG90820.1 - 1.4 8.5 20.7 0.085 12.4 14.9 1.9 2 0 0 2 2 2 0 DDRGK domain Pkinase PF00069.25 GBG90821.1 - 2.5e-22 79.5 0.0 7.5e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG90821.1 - 1e-18 67.6 0.0 2.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3584 PF12128.8 GBG90821.1 - 0.0036 14.9 2.8 0.0045 14.6 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) GAS PF13851.6 GBG90821.1 - 0.0048 16.3 10.1 0.008 15.6 10.1 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Focal_AT PF03623.13 GBG90821.1 - 0.0067 16.4 3.0 0.0088 16.0 2.2 1.6 2 0 0 2 2 1 1 Focal adhesion targeting region GOLGA2L5 PF15070.6 GBG90821.1 - 0.0096 14.6 5.4 0.013 14.2 5.4 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Cep57_CLD_2 PF14197.6 GBG90821.1 - 0.017 15.2 12.2 0.03 14.4 4.0 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 GBG90821.1 - 0.026 14.4 13.1 0.034 14.0 12.5 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 GBG90821.1 - 0.027 13.8 5.6 0.037 13.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 GBG90821.1 - 0.043 13.8 15.1 0.087 12.8 15.1 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LUC7 PF03194.15 GBG90821.1 - 0.058 13.0 4.7 5.1 6.7 4.7 2.1 1 1 0 1 1 1 0 LUC7 N_terminus Viral_DNA_bp PF00747.17 GBG90821.1 - 0.075 10.2 2.1 0.095 9.8 2.1 1.0 1 0 0 1 1 1 0 ssDNA binding protein ERM PF00769.19 GBG90821.1 - 0.13 12.1 9.9 0.16 11.8 9.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CLZ PF16526.5 GBG90821.1 - 0.13 12.6 8.5 2.3 8.7 3.8 3.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF724 PF05266.14 GBG90821.1 - 0.14 11.9 7.4 0.23 11.3 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Lectin_N PF03954.14 GBG90821.1 - 0.14 11.9 2.0 0.13 12.0 0.4 1.8 2 0 0 2 2 1 0 Hepatic lectin, N-terminal domain Tektin PF03148.14 GBG90821.1 - 0.21 10.3 9.9 1.4 7.6 9.9 1.9 1 1 0 1 1 1 0 Tektin family Spc7 PF08317.11 GBG90821.1 - 0.25 10.2 9.4 0.44 9.4 9.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 GBG90821.1 - 0.25 11.4 9.8 0.4 10.7 9.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 GBG90821.1 - 0.37 11.3 3.3 7.7 7.1 1.8 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4515 PF14988.6 GBG90821.1 - 0.39 10.5 11.7 1.2 8.9 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) Spc24 PF08286.11 GBG90821.1 - 0.45 10.8 10.7 0.47 10.7 6.6 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fez1 PF06818.15 GBG90821.1 - 0.46 10.9 10.3 15 5.9 12.0 1.9 1 1 1 2 2 2 0 Fez1 Syntaxin-6_N PF09177.11 GBG90821.1 - 0.51 10.9 7.8 0.94 10.1 4.8 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CALCOCO1 PF07888.11 GBG90821.1 - 0.76 8.6 13.3 1.4 7.7 13.3 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like APG6_N PF17675.1 GBG90821.1 - 1.4 9.4 14.6 0.76 10.3 10.4 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 GBG90821.1 - 1.8 8.6 7.1 2.1 8.4 4.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 GBG90821.1 - 1.9 8.9 12.7 16 6.0 9.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4472 PF14739.6 GBG90821.1 - 1.9 9.2 10.6 1.1 10.0 6.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Fzo_mitofusin PF04799.13 GBG90821.1 - 2.2 7.8 6.5 3.4 7.2 4.9 2.0 1 1 1 2 2 2 0 fzo-like conserved region Atg14 PF10186.9 GBG90821.1 - 2.7 7.0 7.5 3.7 6.5 7.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KELK PF15796.5 GBG90821.1 - 3.9 8.0 12.0 2.8 8.4 8.4 2.2 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ZapB PF06005.12 GBG90821.1 - 4.2 7.9 16.2 0.41 11.1 8.9 2.4 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 GBG90821.1 - 4.3 8.0 10.4 8.5 7.1 5.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF848 PF05852.11 GBG90821.1 - 5.3 7.2 9.2 23 5.1 6.3 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) bZIP_1 PF00170.21 GBG90821.1 - 8.6 6.6 15.3 5.5 7.2 3.9 3.4 2 1 1 3 3 3 0 bZIP transcription factor Paralemmin PF03285.15 GBG90821.1 - 9.1 5.8 8.8 9.8 5.7 6.3 1.9 1 1 1 2 2 2 0 Paralemmin CG-1 PF03859.16 GBG90823.1 - 1.5e-45 153.8 2.2 1.5e-45 153.8 2.2 2.3 2 0 0 2 2 2 1 CG-1 domain IQ PF00612.27 GBG90823.1 - 9.7e-09 34.3 20.1 0.0012 18.4 0.3 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif Ank_2 PF12796.7 GBG90823.1 - 0.00016 22.2 0.0 0.00054 20.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GBG90823.1 - 0.009 16.6 0.1 0.052 14.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GBG90823.1 - 0.071 13.7 0.0 0.33 11.7 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat PXA PF02194.15 GBG90823.1 - 0.35 10.8 1.9 1.3 9.0 1.9 2.0 1 0 0 1 1 1 0 PXA domain PPR_2 PF13041.6 GBG90825.1 - 2.3e-28 98.1 0.3 7e-07 29.3 0.0 6.1 4 1 2 6 6 6 5 PPR repeat family PPR_3 PF13812.6 GBG90825.1 - 3.7e-19 68.6 9.9 4.4e-06 26.7 0.1 6.1 4 1 2 6 6 5 3 Pentatricopeptide repeat domain PPR PF01535.20 GBG90825.1 - 6e-18 63.8 7.9 0.0085 16.3 0.1 8.0 8 1 0 8 8 8 5 PPR repeat PPR_1 PF12854.7 GBG90825.1 - 1.2e-11 44.1 0.0 0.059 13.1 0.0 6.6 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 GBG90825.1 - 8.3e-09 35.1 6.9 2.1e-06 27.3 0.1 3.6 2 1 1 4 4 3 2 Pentacotripeptide-repeat region of PRORP DUF1664 PF07889.12 GBG90825.1 - 0.0094 16.0 3.7 0.0094 16.0 3.7 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) LMBR1 PF04791.16 GBG90825.1 - 0.26 10.2 12.2 0.74 8.7 12.2 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF5069 PF16798.5 GBG90825.1 - 0.69 10.1 9.5 1.6 8.9 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) DNA_pack_N PF02500.15 GBG90825.1 - 2 8.1 4.5 0.71 9.7 0.1 2.2 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus DUF2408 PF10303.9 GBG90825.1 - 2.5 8.7 17.9 5.7 7.5 7.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) FKS1_dom1 PF14288.6 GBG90825.1 - 7.2 7.0 0.0 7.2 7.0 0.0 3.6 5 0 0 5 5 4 0 1,3-beta-glucan synthase subunit FKS1, domain-1 CDC45 PF02724.14 GBG90826.1 - 0.65 8.2 14.9 0.85 7.8 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG90826.1 - 0.78 9.0 18.4 0.98 8.7 18.4 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG90826.1 - 2.1 6.5 20.4 2.8 6.1 20.4 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG90826.1 - 2.3 7.5 10.8 3.3 6.9 10.8 1.1 1 0 0 1 1 1 0 NOA36 protein Coilin_N PF15862.5 GBG90826.1 - 2.4 8.0 8.7 7.2 6.4 8.5 2.0 2 0 0 2 2 2 0 Coilin N-terminus TFIIF_alpha PF05793.12 GBG90826.1 - 2.5 6.6 19.5 3.1 6.3 19.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRN3 PF05327.11 GBG90826.1 - 7.9 4.9 9.1 10 4.5 9.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RVT_1 PF00078.27 GBG90827.1 - 6.4e-32 110.9 0.1 9.6e-32 110.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90827.1 - 2.7e-17 62.6 0.0 6.3e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90827.1 - 6.8e-05 23.1 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90828.1 - 2.2e-18 66.1 0.2 5.4e-18 64.9 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG90828.1 - 1.5e-12 47.5 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90828.1 - 2.8e-08 34.0 0.0 6.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG90828.1 - 5.1e-08 32.8 0.0 9.8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90828.1 - 6.5e-06 26.7 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90828.1 - 4.7e-05 23.9 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG90828.1 - 0.0092 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF1997 PF09366.10 GBG90829.1 - 9.9e-28 97.2 0.0 1.6e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) DDE_Tnp_4 PF13359.6 GBG90830.1 - 6.3e-17 61.7 0.0 2.5e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90830.1 - 1.1e-07 31.6 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90830.1 - 0.011 15.3 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain Na_trans_assoc PF06512.13 GBG90832.1 - 0.025 14.9 7.4 0.036 14.4 7.4 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated RT_RNaseH PF17917.1 GBG90833.1 - 4.4e-20 71.9 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90833.1 - 8.8e-12 44.9 0.0 2.3e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG90833.1 - 4.8e-06 27.1 0.0 9.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90833.1 - 0.00016 22.3 0.0 0.00033 21.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 GBG90834.1 - 2.2e-21 75.3 1.6 1.5e-20 72.7 1.6 1.9 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GBG90834.1 - 2.6e-08 33.6 0.4 1.7e-07 30.9 0.4 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GBG90834.1 - 0.018 15.5 0.3 0.79 10.2 0.1 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 GBG90834.1 - 0.037 14.1 1.0 0.88 9.7 0.3 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Ribosomal_L40e PF01020.17 GBG90834.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L40e family YL1 PF05764.13 GBG90836.1 - 0.0061 16.7 31.9 0.011 15.8 31.9 1.3 1 0 0 1 1 1 1 YL1 nuclear protein RNA_pol_Rpc4 PF05132.14 GBG90836.1 - 0.0073 16.8 13.9 0.014 15.8 13.9 1.5 1 0 0 1 1 1 1 RNA polymerase III RPC4 PTPRCAP PF15713.5 GBG90836.1 - 0.051 13.9 15.6 0.16 12.3 15.6 1.8 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Neur_chan_memb PF02932.16 GBG90836.1 - 0.074 13.1 2.5 0.1 12.6 2.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RPOL_N PF14700.6 GBG90836.1 - 0.083 12.3 13.0 0.11 11.9 13.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal SAPS PF04499.15 GBG90836.1 - 0.12 11.2 5.1 0.16 10.7 5.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SRP-alpha_N PF04086.13 GBG90836.1 - 0.13 12.2 22.8 0.21 11.5 22.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF5308 PF17233.2 GBG90836.1 - 0.39 10.9 2.6 0.7 10.1 2.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DDHD PF02862.17 GBG90836.1 - 0.61 10.2 7.4 0.96 9.6 7.4 1.2 1 0 0 1 1 1 0 DDHD domain DUF2052 PF09747.9 GBG90836.1 - 0.83 9.7 21.0 1.6 8.8 21.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF1764 PF08576.10 GBG90836.1 - 1.1 10.2 34.6 2.2 9.2 34.6 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3807 PF12720.7 GBG90836.1 - 1.2 9.4 29.2 2.1 8.6 29.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) AAA_11 PF13086.6 GBG90836.1 - 1.8 8.3 15.4 2.9 7.6 15.4 1.2 1 0 0 1 1 1 0 AAA domain Tim54 PF11711.8 GBG90836.1 - 2.3 6.9 19.0 3.5 6.3 19.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 VIR_N PF15912.5 GBG90836.1 - 4.7 6.7 11.3 8.5 5.9 11.3 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal PPL5 PF18168.1 GBG90836.1 - 5.3 6.2 18.5 7.9 5.7 18.5 1.2 1 0 0 1 1 1 0 Prim-pol family 5 CENP-N PF05238.13 GBG90836.1 - 8.5 5.6 15.4 12 5.0 15.4 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Nop53 PF07767.11 GBG90836.1 - 9.9 5.4 40.2 15 4.8 40.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RVT_1 PF00078.27 GBG90843.1 - 6.2e-20 71.7 0.0 9.1e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IGF2_C PF08365.11 GBG90844.1 - 3 7.9 5.9 22 5.1 3.0 2.7 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide Flagellin_C PF00700.21 GBG90846.1 - 0.047 14.1 1.3 0.3 11.5 0.2 2.7 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region eIF3g PF12353.8 GBG90846.1 - 0.09 13.2 0.3 0.49 10.8 0.2 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Snapin_Pallidin PF14712.6 GBG90846.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.8 1 1 0 2 2 2 0 Snapin/Pallidin Phycobilisome PF00502.19 GBG90846.1 - 0.51 10.3 3.3 23 4.9 0.0 2.7 2 1 0 2 2 2 0 Phycobilisome protein AAA_16 PF13191.6 GBG90846.1 - 7.3 6.9 8.9 0.57 10.6 0.4 2.5 2 1 0 2 2 2 0 AAA ATPase domain Mito_fiss_reg PF05308.11 GBG90846.1 - 8 6.5 18.8 4 7.5 9.9 2.4 1 1 1 2 2 2 0 Mitochondrial fission regulator RVT_1 PF00078.27 GBG90847.1 - 5.1e-06 26.2 0.0 9.7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LZ3wCH PF18517.1 GBG90847.1 - 0.054 13.6 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 Leucine zipper with capping helix domain RVT_1 PF00078.27 GBG90848.1 - 5.3e-21 75.2 0.2 1.2e-20 74.0 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG90848.1 - 9e-05 23.0 0.0 0.00026 21.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90848.1 - 0.0034 17.9 0.0 0.0078 16.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG90848.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 GBG90849.1 - 2.4e-39 133.4 0.2 6.4e-23 80.7 0.1 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90849.1 - 1.1e-34 118.9 1.3 7.8e-30 103.3 0.5 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90849.1 - 2.2e-30 105.9 0.1 3.4e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90849.1 - 9.1e-21 73.7 0.2 1.9e-20 72.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90849.1 - 3.6e-06 27.2 0.0 1e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG90849.1 - 0.0012 19.1 0.0 0.0057 16.8 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG90851.1 - 1.6e-28 99.1 0.2 3.5e-28 97.9 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90851.1 - 4.4e-21 74.8 0.0 8.8e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90851.1 - 2.1e-19 69.4 0.1 4.8e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG90851.1 - 0.0032 17.7 0.0 0.0079 16.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG90851.1 - 0.0034 17.5 0.0 0.0085 16.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG90852.1 - 0.0009 19.5 1.6 0.0094 16.2 0.1 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4407 PF14362.6 GBG90852.1 - 0.2 11.0 11.6 0.28 10.5 9.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AIF-MLS PF14962.6 GBG90852.1 - 1 9.3 8.1 2.4 8.1 8.1 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence rve PF00665.26 GBG90856.1 - 0.051 13.8 0.0 0.23 11.7 0.0 2.2 1 0 0 1 1 1 0 Integrase core domain Chromo PF00385.24 GBG90856.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2339 PF10101.9 GBG90856.1 - 0.13 10.8 71.1 0.0022 16.7 24.5 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2339) DUF659 PF04937.15 GBG90858.1 - 8e-22 77.7 0.0 1.8e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pkinase_Tyr PF07714.17 GBG90859.1 - 1.6e-39 135.7 0.0 1.4e-38 132.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90859.1 - 6.7e-39 133.8 0.0 9.5e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG90859.1 - 0.069 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GBG90860.1 - 1.6e-37 129.2 0.0 4.2e-37 127.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG90860.1 - 1e-35 123.4 0.0 1.5e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG90860.1 - 0.0093 15.9 0.0 0.047 13.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG90860.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RVT_1 PF00078.27 GBG90861.1 - 3e-26 92.3 0.1 5.4e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90861.1 - 6.6e-26 90.3 0.0 4.8e-25 87.5 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90861.1 - 1.4e-23 83.1 0.0 3.3e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90861.1 - 1.1e-13 51.1 0.1 3.4e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG90861.1 - 8.6e-07 29.5 0.0 1.2e-05 25.8 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90861.1 - 1.4e-06 28.8 0.2 1.3e-05 25.7 0.0 2.6 3 0 0 3 3 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG90861.1 - 7.3e-05 22.6 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Plexin_cytopl PF08337.12 GBG90861.1 - 0.0089 14.8 0.5 0.026 13.2 0.5 1.7 1 1 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Asp_protease PF09668.10 GBG90861.1 - 0.041 13.7 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 GBG90861.1 - 0.059 13.6 0.0 0.33 11.2 0.0 2.3 1 0 0 1 1 1 0 Integrase core domain DUF4407 PF14362.6 GBG90861.1 - 3.6 6.8 13.9 2.7 7.3 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DHC_N2 PF08393.13 GBG90862.1 - 3.2e-110 369.0 3.2 3.9e-110 368.7 3.2 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Ribosomal_S7e PF01251.18 GBG90863.1 - 1.1e-82 276.2 2.4 1.3e-82 276.0 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Herpes_BLRF2 PF05812.12 GBG90863.1 - 0.084 13.0 0.4 0.21 11.7 0.3 1.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein WcbI PF18588.1 GBG90863.1 - 0.1 12.2 0.6 0.37 10.4 0.1 1.8 1 1 1 2 2 2 0 Polysaccharide biosynthesis enzyme WcbI RT_RNaseH PF17917.1 GBG90864.1 - 6e-22 77.9 0.0 1.3e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90864.1 - 6.2e-22 77.5 0.0 1.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG90864.1 - 2.6e-05 24.1 1.2 5.1e-05 23.2 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG90864.1 - 0.38 10.6 1.9 0.76 9.7 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Nop14 PF04147.12 GBG90864.1 - 0.71 8.0 6.2 1.1 7.4 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG90864.1 - 6.4 4.9 7.7 9.3 4.4 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 GBG90865.1 - 5.6 7.0 21.4 1.7 8.7 1.6 3.4 2 1 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) DHC_N2 PF08393.13 GBG90866.1 - 1.2e-17 64.1 2.0 1.8e-16 60.3 0.2 2.2 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 RVP_2 PF08284.11 GBG90866.1 - 6.4e-06 26.0 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG90866.1 - 1.2e-05 25.8 0.0 2.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90866.1 - 0.00014 22.5 0.0 0.00032 21.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG90866.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease LMP PF04778.12 GBG90866.1 - 0.061 13.2 0.4 0.32 10.9 0.4 2.0 1 1 1 2 2 2 0 LMP repeated region Integrase_H2C2 PF17921.1 GBG90868.1 - 2e-42 143.1 2.2 8.2e-21 73.9 0.2 2.5 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90868.1 - 1.3e-29 102.6 0.1 2.5e-29 101.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90868.1 - 2.6e-23 82.4 0.0 4.2e-15 56.0 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain RT_RNaseH_2 PF17919.1 GBG90868.1 - 8.4e-23 80.3 0.0 1.5e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG90868.1 - 1.3e-08 34.9 0.0 0.00056 20.1 0.0 2.7 2 0 0 2 2 2 2 H2C2 zinc finger DUF2862 PF11061.8 GBG90868.1 - 0.085 12.7 0.1 0.41 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) Synaptobrevin PF00957.21 GBG90868.1 - 0.15 11.9 0.5 23 4.8 0.1 2.4 2 0 0 2 2 2 0 Synaptobrevin Cys_rich_CPXG PF14255.6 GBG90868.1 - 0.54 10.2 4.1 13 5.8 0.6 2.5 2 0 0 2 2 2 0 Cysteine-rich CPXCG N6_N4_Mtase PF01555.18 GBG90869.1 - 3.1e-07 30.3 0.0 6.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 DNA methylase SpvD PF05563.12 GBG90870.1 - 0.055 13.1 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD DUF3148 PF11347.8 GBG90872.1 - 1.6e-27 95.0 0.1 2.8e-27 94.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3148) DUF659 PF04937.15 GBG90873.1 - 6.2e-34 117.0 0.3 1.1e-33 116.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90873.1 - 5e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ribosomal_L19 PF01245.20 GBG90874.1 - 2.8e-15 56.2 0.1 5.9e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Nop14 PF04147.12 GBG90874.1 - 1.2 7.3 10.6 1.6 6.8 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family Isochorismatase PF00857.20 GBG90875.1 - 1.8e-18 67.3 0.0 4.1e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family DUF1943 PF09172.11 GBG90875.1 - 0.027 13.7 4.0 0.049 12.9 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) RVT_1 PF00078.27 GBG90877.1 - 5e-30 104.7 0.0 7.3e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG90877.1 - 0.0051 17.4 0.0 0.017 15.7 0.0 1.9 2 1 0 2 2 2 1 Aspartyl protease PTCB-BRCT PF12738.7 GBG90878.1 - 0.083 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain OrfB_IS605 PF01385.19 GBG90878.1 - 0.16 12.2 2.8 6 7.1 0.1 2.7 2 0 0 2 2 2 0 Probable transposase CheY-binding PF09078.11 GBG90878.1 - 4.3 7.5 13.7 0.54 10.4 0.3 4.1 4 1 1 5 5 5 0 CheY binding DivIC PF04977.15 GBG90878.1 - 9.3 6.1 19.9 7.5 6.4 0.4 5.3 4 1 1 5 5 5 0 Septum formation initiator DUF1805 PF08827.11 GBG90879.1 - 0.083 13.2 0.1 0.58 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Cwf_Cwc_15 PF04889.12 GBG90884.1 - 0.11 12.2 4.5 0.17 11.6 0.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mito_fiss_reg PF05308.11 GBG90884.1 - 1.2 9.2 4.4 1.5 8.8 0.2 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF659 PF04937.15 GBG90886.1 - 3.5e-15 56.2 0.0 5.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Peptidase_C48 PF02902.19 GBG90888.1 - 5.4e-22 78.7 0.0 1.1e-21 77.7 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF659 PF04937.15 GBG90889.1 - 4.7e-07 29.8 0.0 8.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90889.1 - 0.007 16.1 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Asp_protease_2 PF13650.6 GBG90889.1 - 0.0078 16.8 0.0 0.02 15.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Ala_racemase_N PF01168.20 GBG90890.1 - 1.3e-20 74.0 0.0 1.7e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Thiolase_N PF00108.23 GBG90890.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF1263 PF06882.12 GBG90890.1 - 0.098 12.7 1.1 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) RVT_1 PF00078.27 GBG90891.1 - 3e-32 111.9 0.0 5e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90891.1 - 6.8e-15 54.9 0.0 4e-14 52.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG90891.1 - 5.4e-09 36.5 0.0 9.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90891.1 - 1.1e-06 29.2 0.0 2.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG90891.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG90891.1 - 0.0004 20.6 0.0 0.0012 19.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG90891.1 - 0.012 15.4 0.6 0.025 14.3 0.1 1.8 2 1 0 2 2 2 0 Aspartyl protease DUF1758 PF05585.12 GBG90891.1 - 0.043 13.6 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 GBG90892.1 - 3.7e-30 103.9 0.0 1.4e-29 102.0 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90892.1 - 9.9e-30 102.9 0.1 4.6e-29 100.8 0.1 2.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APC_N_CC PF16689.5 GBG90892.1 - 0.14 12.3 8.1 1.7 8.8 0.2 4.9 3 1 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain PCEMA1 PF07418.11 GBG90893.1 - 1.7 8.1 17.8 2.5 7.5 17.8 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 RVT_1 PF00078.27 GBG90894.1 - 2.8e-29 102.2 0.0 5.4e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90894.1 - 1.2e-17 63.7 0.1 2.7e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90894.1 - 1.6e-08 34.8 1.2 4.2e-08 33.4 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG90894.1 - 1.4e-07 31.5 0.0 6.5e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG90894.1 - 2.2e-07 31.4 0.0 7.1e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90894.1 - 1.9e-05 25.2 0.0 7.5e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG90894.1 - 2.9e-05 23.9 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG90894.1 - 0.0089 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease WTX PF09422.10 GBG90894.1 - 0.014 14.5 2.0 0.023 13.8 2.0 1.2 1 0 0 1 1 1 0 WTX protein NPV_P10 PF05531.12 GBG90896.1 - 1.8 9.1 5.0 1.2e+02 3.3 5.0 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RVT_1 PF00078.27 GBG90897.1 - 2.5e-28 99.1 0.0 3.7e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90897.1 - 2.1e-10 40.8 0.0 5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG90897.1 - 2e-07 30.8 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90897.1 - 1.6e-06 28.6 0.0 3.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90897.1 - 1.5e-05 25.5 0.0 2.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG90897.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease CENP-K PF11802.8 GBG90898.1 - 0.0023 17.6 3.8 0.0033 17.1 3.8 1.2 1 0 0 1 1 1 1 Centromere-associated protein K TMEM247 PF15444.6 GBG90898.1 - 0.0036 17.4 0.1 0.0036 17.4 0.1 2.0 2 1 0 2 2 2 1 Transmembrane protein 247 TFIIA PF03153.13 GBG90898.1 - 0.16 12.0 15.4 0.2 11.6 15.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MCU PF04678.13 GBG90898.1 - 0.73 9.9 6.1 0.35 11.0 1.0 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Beta_helix PF13229.6 GBG90899.1 - 5.5e-06 26.3 19.3 0.0065 16.3 6.0 3.4 1 1 2 3 3 3 3 Right handed beta helix region Chondroitinas_B PF14592.6 GBG90899.1 - 0.018 13.9 0.0 0.044 12.7 0.0 1.6 2 0 0 2 2 2 0 Chondroitinase B Lactamase_B_2 PF12706.7 GBG90899.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain WD40 PF00400.32 GBG90901.1 - 2.8e-42 141.9 11.3 9.3e-06 26.3 0.1 9.7 9 0 0 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG90901.1 - 8e-13 48.5 1.4 0.013 15.8 0.1 6.3 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GBG90901.1 - 4e-07 29.8 0.2 2 8.4 0.0 5.2 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 GBG90901.1 - 2.9e-05 24.0 0.0 0.033 14.1 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GBG90901.1 - 4.2e-05 22.7 0.2 0.023 13.6 0.0 3.4 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 GBG90901.1 - 0.00021 19.8 0.0 0.86 7.8 0.0 3.0 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz AAA PF00004.29 GBG90902.1 - 2.9e-33 115.1 0.0 6.4e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG90902.1 - 4.1e-10 39.3 0.0 8.6e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GBG90902.1 - 5.4e-06 26.5 0.3 4.1e-05 23.6 0.3 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG90902.1 - 0.00054 19.7 0.0 0.0041 16.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GBG90902.1 - 0.0019 18.6 0.1 0.049 14.0 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG90902.1 - 0.0022 18.3 0.3 0.065 13.5 0.2 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GBG90902.1 - 0.0023 17.7 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 GBG90902.1 - 0.0063 16.7 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GBG90902.1 - 0.0065 17.0 0.0 0.017 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GBG90902.1 - 0.017 15.2 0.0 0.057 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 GBG90902.1 - 0.036 13.6 0.2 0.65 9.5 0.0 2.3 1 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GBG90902.1 - 0.061 13.7 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Sigma54_activ_2 PF14532.6 GBG90902.1 - 0.065 13.4 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 GBG90902.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GBG90902.1 - 0.14 11.5 0.1 0.49 9.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 GBG90903.1 - 2.5e-33 115.3 0.0 5.6e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GBG90903.1 - 3.6e-10 39.5 0.0 7.8e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GBG90903.1 - 4.3e-06 26.8 0.3 3.6e-05 23.8 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GBG90903.1 - 0.00045 20.0 0.0 0.0037 17.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GBG90903.1 - 0.0015 18.9 0.1 0.054 13.9 0.0 2.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GBG90903.1 - 0.0018 18.6 0.3 0.059 13.7 0.2 2.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GBG90903.1 - 0.0021 17.8 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 GBG90903.1 - 0.0054 16.9 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GBG90903.1 - 0.0056 17.2 0.0 0.015 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GBG90903.1 - 0.015 15.5 0.0 0.051 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 GBG90903.1 - 0.03 13.9 0.2 0.51 9.9 0.1 2.3 1 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 GBG90903.1 - 0.051 13.7 0.0 0.99 9.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 GBG90903.1 - 0.053 13.9 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 GBG90903.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GBG90903.1 - 0.12 11.7 0.1 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 GBG90903.1 - 0.22 10.9 0.1 2.8 7.2 0.0 2.2 1 1 1 2 2 2 0 KaiC RVT_1 PF00078.27 GBG90904.1 - 4.3e-27 95.1 0.0 8.7e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG90904.1 - 5.4e-09 35.9 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90904.1 - 5.3e-08 33.4 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90904.1 - 1.6e-06 28.6 0.0 3.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG90904.1 - 0.0028 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF659 PF04937.15 GBG90906.1 - 2.4e-19 69.7 0.0 3.5e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Arf PF00025.21 GBG90908.1 - 1.4e-43 148.4 0.0 1.6e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GBG90908.1 - 2.6e-09 37.3 0.0 3.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GBG90908.1 - 1e-08 34.8 0.1 2e-08 33.8 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 GBG90908.1 - 9.8e-08 31.6 0.0 1.1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 GBG90908.1 - 4.7e-05 23.0 0.0 5.9e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GBG90908.1 - 0.00014 21.3 0.0 0.00017 21.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MPM1 PF17234.2 GBG90908.1 - 0.16 12.2 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Tau95 PF09734.9 GBG90909.1 - 0.033 15.0 2.1 0.063 14.1 2.1 1.4 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Apolipo_F PF15148.6 GBG90909.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein F DUF2681 PF10883.8 GBG90909.1 - 0.28 11.6 3.4 0.61 10.5 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) zf-CCHC PF00098.23 GBG90909.1 - 0.3 11.2 5.7 0.7 10.1 5.7 1.7 1 0 0 1 1 1 0 Zinc knuckle DIOX_N PF14226.6 GBG90909.1 - 0.35 11.6 2.4 0.85 10.4 2.4 1.6 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Ribosomal_L27e PF01777.18 GBG90910.1 - 1.1e-33 115.4 10.0 1.1e-33 115.4 10.0 1.4 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 GBG90910.1 - 0.0034 17.3 0.2 0.0098 15.8 0.2 1.9 1 0 0 1 1 1 1 KOW motif DUF1713 PF08213.11 GBG90911.1 - 6.7e-09 35.5 16.4 1.2e-08 34.7 16.4 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) zf-CCHC PF00098.23 GBG90912.1 - 1.5e-05 24.9 3.9 1.5e-05 24.9 3.9 2.2 2 0 0 2 2 2 1 Zinc knuckle NBD_C PF17042.5 GBG90912.1 - 7.3 7.1 8.4 8.4 6.9 7.0 1.8 1 1 0 1 1 1 0 Nucleotide-binding C-terminal domain Mut7-C PF01927.16 GBG90913.1 - 4.9e-21 75.4 0.1 1.4e-20 73.9 0.1 1.8 1 0 0 1 1 1 1 Mut7-C RNAse domain DNA_pol_A_exo1 PF01612.20 GBG90913.1 - 9.3e-12 45.0 0.0 1.8e-08 34.3 0.0 3.1 3 0 0 3 3 3 2 3'-5' exonuclease Mut7-C PF01927.16 GBG90914.1 - 5.1e-34 117.5 0.3 1.3e-33 116.2 0.3 1.7 1 0 0 1 1 1 1 Mut7-C RNAse domain DNA_pol_A_exo1 PF01612.20 GBG90914.1 - 9.8e-12 44.9 0.0 1.8e-08 34.3 0.0 3.1 3 0 0 3 3 3 2 3'-5' exonuclease RT_RNaseH_2 PF17919.1 GBG90915.1 - 1e-21 76.8 0.0 2.5e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90915.1 - 2.7e-21 75.8 0.0 7.6e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90915.1 - 1.2e-08 34.8 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG90915.1 - 0.0032 18.0 0.0 0.0093 16.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG90915.1 - 0.0048 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG90915.1 - 0.044 13.6 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4373 PF14297.6 GBG90915.1 - 0.19 12.5 0.7 0.61 10.9 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) BORG_CEP PF14957.6 GBG90915.1 - 3.5 8.8 6.9 2.3 9.4 0.4 2.5 2 0 0 2 2 2 0 Cdc42 effector INTS5_C PF14838.6 GBG90917.1 - 1.3e-06 27.4 0.8 1.1e-05 24.3 1.7 2.0 2 0 0 2 2 2 1 Integrator complex subunit 5 C-terminus DUF2722 PF10846.8 GBG90917.1 - 0.029 13.3 8.9 0.046 12.7 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 GBG90917.1 - 0.059 13.4 11.5 0.11 12.5 11.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAT1 PF06391.13 GBG90917.1 - 0.11 12.3 4.5 0.18 11.6 4.5 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Roughex PF06020.11 GBG90917.1 - 0.13 11.3 6.2 0.24 10.5 6.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Perilipin PF03036.16 GBG90917.1 - 0.14 11.2 7.8 0.22 10.5 7.8 1.2 1 0 0 1 1 1 0 Perilipin family Activator_LAG-3 PF11498.8 GBG90917.1 - 0.17 10.8 16.7 0.28 10.1 16.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.14 GBG90917.1 - 0.41 10.6 5.5 0.68 9.9 5.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 GBG90917.1 - 2.3 8.8 12.3 0.39 11.4 6.7 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 GBG90917.1 - 7.2 6.2 20.5 12 5.5 20.5 1.2 1 0 0 1 1 1 0 Spt20 family MMS1_N PF10433.9 GBG90918.1 - 2.3e-56 191.4 0.0 4.8e-44 150.8 0.0 2.1 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GBG90918.1 - 2.2e-23 83.1 0.0 1.6e-11 44.1 0.0 3.3 3 0 0 3 3 3 3 CPSF A subunit region RT_RNaseH PF17917.1 GBG90918.1 - 5.5e-21 74.8 0.0 2.4e-20 72.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90918.1 - 2.1e-20 72.6 0.0 1.4e-19 69.9 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90918.1 - 6.2e-19 68.4 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90918.1 - 1.3e-13 50.8 0.0 3.1e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain TolA_bind_tri PF16331.5 GBG90918.1 - 0.22 11.6 6.6 0.52 10.4 6.6 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Fez1 PF06818.15 GBG90918.1 - 3 8.2 5.8 0.69 10.3 0.4 2.1 2 0 0 2 2 2 0 Fez1 Myb_DNA-bind_4 PF13837.6 GBG90919.1 - 5.2e-09 36.4 2.4 5.2e-09 36.4 2.4 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain PcfJ PF14284.6 GBG90919.1 - 0.071 13.0 0.2 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 PcfJ-like protein Pex19 PF04614.12 GBG90919.1 - 0.13 12.0 2.2 0.078 12.7 0.2 1.5 2 0 0 2 2 2 0 Pex19 protein family Gln-synt_C PF00120.24 GBG90920.1 - 6.4e-39 133.9 0.0 1.6e-38 132.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain RVT_1 PF00078.27 GBG90920.1 - 3.7e-08 33.1 0.0 5.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 GBG90920.1 - 0.019 14.8 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG90920.1 - 0.021 15.4 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG90920.1 - 0.043 14.5 0.0 0.096 13.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG90921.1 - 3.4e-27 95.4 0.1 1.1e-26 93.7 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG90921.1 - 4.8e-19 68.2 0.3 1.2e-18 66.9 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90921.1 - 8.2e-14 51.8 0.0 1.7e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90921.1 - 1.4e-08 34.7 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Gln-synt_C PF00120.24 GBG90921.1 - 7.4e-07 28.5 0.0 1.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain gag-asp_proteas PF13975.6 GBG90921.1 - 1e-06 29.2 0.0 1.9e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG90921.1 - 2.9e-05 23.8 0.0 5.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG90921.1 - 4.7e-05 24.0 0.0 8.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG90921.1 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG90921.1 - 0.054 13.7 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger Pep1_7 PF17232.2 GBG90922.1 - 0.0078 16.7 0.4 0.2 12.1 0.0 2.5 2 0 0 2 2 2 1 Elicitor peptide 1-7 Retrotrans_gag PF03732.17 GBG90922.1 - 3.6 7.9 10.8 0.11 12.8 2.8 2.7 2 1 0 2 2 2 0 Retrotransposon gag protein dsrm PF00035.26 GBG90924.1 - 0.00052 20.7 0.0 0.0019 18.8 0.0 2.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Retrotrans_gag PF03732.17 GBG90925.1 - 1.8e-05 24.9 4.6 0.00026 21.2 0.1 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein ADIP PF11559.8 GBG90925.1 - 0.019 15.0 1.7 0.019 15.0 1.7 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 GBG90925.1 - 0.32 11.5 2.7 2.8 8.5 0.4 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 GBG90925.1 - 2.7 8.7 12.5 0.45 11.2 0.2 3.5 3 0 0 3 3 3 0 SlyX HIP1_clath_bdg PF16515.5 GBG90925.1 - 3 8.5 17.5 0.082 13.5 1.8 3.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Amidohydro_2 PF04909.14 GBG90926.1 - 2.4e-11 44.0 0.0 3.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M16 PF00675.20 GBG90927.1 - 0.21 11.6 4.2 0.38 10.7 4.2 1.4 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) Complex1_LYR PF05347.15 GBG90928.1 - 6.6e-13 48.5 0.7 1.1e-12 47.8 0.7 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GBG90928.1 - 5.2e-05 23.9 0.5 0.0001 23.0 0.5 1.4 1 0 0 1 1 1 1 Complex1_LYR-like HpaP PF09483.10 GBG90928.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Complex1_LYR PF05347.15 GBG90929.1 - 3.6e-06 26.9 0.2 5.8e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GBG90929.1 - 0.035 14.9 0.7 0.049 14.4 0.7 1.3 1 0 0 1 1 1 0 Complex1_LYR-like HpaP PF09483.10 GBG90929.1 - 0.063 13.5 0.4 0.12 12.7 0.0 1.5 2 0 0 2 2 2 0 Type III secretion protein (HpaP) RVT_3 PF13456.6 GBG90929.1 - 0.089 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like zf-CCHC PF00098.23 GBG90930.1 - 9.3e-08 31.8 1.0 1.8e-07 30.9 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG90930.1 - 0.0035 17.2 0.1 0.0085 15.9 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG90930.1 - 0.0084 16.1 1.9 0.016 15.2 1.0 2.1 2 0 0 2 2 2 1 Zinc knuckle AAA_23 PF13476.6 GBG90930.1 - 0.0098 16.4 6.4 0.014 15.9 6.4 1.2 1 0 0 1 1 1 1 AAA domain zf-CCHC_4 PF14392.6 GBG90930.1 - 0.024 14.4 0.3 0.057 13.1 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG90930.1 - 0.048 13.5 3.5 0.54 10.1 1.2 2.3 2 0 0 2 2 2 0 Zinc knuckle DDRGK PF09756.9 GBG90930.1 - 1.7 8.2 24.3 0.041 13.5 18.0 1.5 2 0 0 2 2 2 0 DDRGK domain SID-1_RNA_chan PF13965.6 GBG90930.1 - 6.2 5.1 4.6 8 4.7 4.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Dimer_Tnp_hAT PF05699.14 GBG90931.1 - 6.9e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG90934.1 - 3.9e-30 104.7 0.0 5.6e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90934.1 - 6e-05 22.8 0.1 0.00011 22.0 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG90935.1 - 3.7e-12 46.3 0.3 7.6e-12 45.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG90936.1 - 0.34 11.1 2.4 0.6 10.3 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG90937.1 - 0.02 14.6 0.1 0.049 13.3 0.1 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG90937.1 - 0.32 11.2 1.9 0.55 10.4 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG90941.1 - 1.9e-14 53.5 0.1 4.7e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG90941.1 - 0.03 14.5 0.6 0.072 13.3 0.6 1.6 1 0 0 1 1 1 0 H2C2 zinc finger TFIIF_beta PF02270.15 GBG90943.1 - 2.9e-25 88.2 0.3 6.2e-25 87.1 0.3 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 GBG90943.1 - 2.9e-08 34.5 0.0 6.8e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Glyco_hydro_38C PF07748.13 GBG90943.1 - 0.068 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain Paz_1 PF18349.1 GBG90943.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 PAZ domain DUF659 PF04937.15 GBG90944.1 - 3.2e-11 43.3 0.5 6.8e-11 42.3 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG90944.1 - 0.015 15.0 0.1 0.038 13.8 0.1 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF2267 PF10025.9 GBG90945.1 - 0.019 15.2 0.1 1.7 8.9 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Roughex PF06020.11 GBG90946.1 - 0.44 9.6 6.8 0.52 9.4 6.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Paf1 PF03985.13 GBG90946.1 - 2.4 7.1 12.4 3.6 6.5 12.4 1.2 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 GBG90946.1 - 7.3 4.6 10.6 9.2 4.2 10.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG90946.1 - 8.2 4.6 8.6 9.5 4.4 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG90947.1 - 1.3e-35 121.5 0.0 2.6e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90947.1 - 2.2e-31 108.2 0.0 5.7e-31 106.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG90947.1 - 2.9e-05 23.9 0.9 5.3e-05 23.1 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-Dof PF02701.15 GBG90947.1 - 0.047 13.9 0.5 0.099 12.8 0.5 1.4 1 0 0 1 1 1 0 Dof domain, zinc finger DUF5617 PF18493.1 GBG90949.1 - 6.4e-05 23.0 2.0 0.00014 21.9 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF5617) DUF2203 PF09969.9 GBG90949.1 - 0.058 14.1 3.6 0.3 11.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) MFAP1 PF06991.11 GBG90949.1 - 0.14 12.0 4.9 0.22 11.3 4.9 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Phage_GPA PF05840.13 GBG90949.1 - 0.63 9.1 4.5 0.89 8.6 4.5 1.1 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) DUF659 PF04937.15 GBG90952.1 - 9.3e-37 126.2 0.2 1.5e-36 125.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Mak16 PF04874.14 GBG90952.1 - 0.0048 17.5 0.1 0.0048 17.5 0.1 3.7 3 1 0 3 3 3 1 Mak16 protein C-terminal region MAP17 PF15807.5 GBG90953.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 GTP1_OBG PF01018.22 GBG90955.1 - 0.07 12.7 2.7 5.5 6.6 2.0 2.5 2 0 0 2 2 2 0 GTP1/OBG DDE_Tnp_4 PF13359.6 GBG90956.1 - 1.4e-15 57.3 0.0 6.4e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90956.1 - 7.1e-07 29.0 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein CTP_transf_1 PF01148.20 GBG90956.1 - 5.1e-05 23.2 9.8 8.4e-05 22.5 9.8 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family DDE_Tnp_1 PF01609.21 GBG90956.1 - 0.02 14.5 0.1 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Transposase DDE domain DEK_C PF08766.11 GBG90957.1 - 0.083 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain Acetyltransf_1 PF00583.25 GBG90958.1 - 1.1e-16 61.1 0.1 1.3e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GBG90958.1 - 4.8e-12 46.1 0.1 6.4e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GBG90958.1 - 4e-11 43.0 0.0 5.3e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GBG90958.1 - 1.7e-07 31.5 0.0 1.9e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GBG90958.1 - 3.3e-05 23.7 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GBG90958.1 - 0.0004 20.5 0.0 0.00049 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GBG90958.1 - 0.00096 18.9 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GBG90958.1 - 0.0052 17.5 0.0 0.006 17.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GBG90958.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF659 PF04937.15 GBG90959.1 - 3.1e-14 53.1 0.0 4.4e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG90962.1 - 1.1e-29 103.6 0.1 1.8e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CHD5 PF04420.14 GBG90963.1 - 0.64 9.9 4.0 1.3 8.9 4.0 1.4 1 0 0 1 1 1 0 CHD5-like protein Histone_H2A_C PF16211.5 GBG90964.1 - 0.14 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 C-terminus of histone H2A APC_N_CC PF16689.5 GBG90964.1 - 0.32 11.1 3.4 0.56 10.3 0.1 2.5 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DDE_Tnp_4 PF13359.6 GBG90965.1 - 2.3e-17 63.1 0.0 2.3e-16 59.8 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG90965.1 - 3.7e-07 29.9 0.0 6.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG90965.1 - 8.7e-05 22.3 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain zf-CCHC PF00098.23 GBG90967.1 - 6.9e-07 29.1 1.9 6.9e-07 29.1 1.9 2.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG90967.1 - 0.0064 16.3 1.1 0.022 14.6 1.1 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG90967.1 - 0.014 15.1 2.0 0.043 13.5 2.0 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RVT_1 PF00078.27 GBG90967.1 - 0.026 14.0 0.0 3.7 7.0 0.0 2.4 1 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF572 PF04502.13 GBG90967.1 - 0.3 10.7 21.2 0.46 10.1 21.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RVT_1 PF00078.27 GBG90968.1 - 3.2e-19 69.3 0.1 1.9e-17 63.5 0.1 2.7 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG90968.1 - 2.2e-06 27.5 0.0 5.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG90968.1 - 2.6e-05 24.4 2.3 3.4e-05 24.0 0.0 2.5 2 1 0 2 2 2 1 Integrase core domain Spt20 PF12090.8 GBG90968.1 - 9.3 5.8 33.6 9.1 5.8 18.5 2.3 2 0 0 2 2 2 0 Spt20 family RT_RNaseH_2 PF17919.1 GBG90969.1 - 4.2e-29 100.5 0.0 8.5e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90969.1 - 2e-25 89.6 0.1 4.9e-25 88.3 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG90969.1 - 3.5e-22 78.7 0.0 1e-21 77.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG90969.1 - 5e-07 29.6 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90969.1 - 3e-05 24.6 0.0 0.00046 20.8 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG90969.1 - 8.3e-05 22.4 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90969.1 - 0.00013 22.5 0.0 0.00062 20.3 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease eIF-1a PF01176.19 GBG90969.1 - 0.017 14.9 0.2 0.041 13.7 0.2 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 rve PF00665.26 GBG90969.1 - 0.018 15.3 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Chromo PF00385.24 GBG90969.1 - 0.055 13.4 1.1 0.4 10.6 0.1 2.7 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC_2 PF13696.6 GBG90969.1 - 0.91 9.4 3.2 1.7 8.5 3.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Med9 PF07544.13 GBG90970.1 - 0.61 10.2 14.6 0.58 10.3 7.7 3.3 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 RT_RNaseH_2 PF17919.1 GBG90971.1 - 1.9e-23 82.4 0.0 4.1e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG90971.1 - 1.1e-21 77.1 0.0 2.3e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90971.1 - 1.3e-18 66.9 0.1 3.5e-18 65.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90971.1 - 2.3e-07 31.0 0.0 1e-06 28.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG90971.1 - 0.0026 17.3 0.0 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG90971.1 - 0.0079 16.4 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG90972.1 - 2.5e-07 31.2 0.0 1.1e-06 29.2 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90972.1 - 1.8e-05 25.2 0.0 6e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG90972.1 - 3.5e-05 23.6 0.0 7.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG90972.1 - 0.0048 17.1 8.2 0.0068 16.7 0.2 3.6 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG90972.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease Use1 PF09753.9 GBG90972.1 - 1.9 8.2 10.9 1 9.0 6.9 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 RT_RNaseH PF17917.1 GBG90973.1 - 5.8e-30 103.7 0.1 1.4e-29 102.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90973.1 - 6.3e-30 103.2 0.0 2.8e-29 101.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG90973.1 - 8.1e-25 87.6 0.6 4.4e-23 82.0 0.2 2.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG90973.1 - 0.0072 16.0 3.8 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Phage capsid scaffolding protein (GPO) serine peptidase FlxA PF14282.6 GBG90973.1 - 0.35 10.9 3.5 1.6 8.8 2.6 2.5 2 0 0 2 2 2 0 FlxA-like protein SICA_beta PF12878.7 GBG90973.1 - 0.56 10.4 2.0 1.2 9.3 2.0 1.4 1 0 0 1 1 1 0 SICA extracellular beta domain TolA_bind_tri PF16331.5 GBG90973.1 - 3.6 7.7 5.4 0.58 10.3 0.4 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Spc7 PF08317.11 GBG90973.1 - 6.2 5.6 9.5 37 3.1 0.0 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DnaB_bind PF10410.9 GBG90975.1 - 0.06 13.5 0.6 1 9.6 0.1 2.3 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase PIF1 PF05970.14 GBG90976.1 - 4.5e-22 78.7 0.0 1e-21 77.5 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase OFCC1 PF15680.5 GBG90976.1 - 0.075 13.6 0.6 0.36 11.4 0.6 2.2 1 0 0 1 1 1 0 Orofacial cleft 1 candidate gene 1 protein DUF4776 PF16003.5 GBG90976.1 - 4.7 6.1 9.6 1.1 8.1 5.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) RVT_1 PF00078.27 GBG90978.1 - 7e-32 110.7 0.0 9.8e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG90979.1 - 5.1e-13 49.3 0.0 9.3e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG90980.1 - 2.9e-08 33.4 0.3 8.5e-08 31.9 0.3 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG90980.1 - 0.0065 16.2 0.5 0.02 14.6 0.5 1.9 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG90980.1 - 0.016 14.8 0.0 0.98 8.9 0.0 2.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG90980.1 - 4.6 7.2 5.5 0.6 10.0 1.0 2.0 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH PF17917.1 GBG90981.1 - 3.4e-26 91.6 0.5 6.8e-26 90.6 0.5 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90981.1 - 1.9e-21 76.0 0.0 3.5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90981.1 - 5.7e-19 68.0 0.7 1.2e-18 66.9 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG90981.1 - 1.1e-15 57.9 0.0 2.7e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG90981.1 - 0.004 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG90982.1 - 3e-24 85.3 0.0 6.7e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90982.1 - 8.1e-17 61.1 0.0 8.7e-10 38.5 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG90982.1 - 4.7e-12 45.6 0.0 1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG90982.1 - 0.002 17.7 0.0 0.074 12.6 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_7 PF12775.7 GBG90983.1 - 4.7e-77 257.6 0.0 7.1e-77 257.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 GBG90983.1 - 5.3e-36 123.5 0.1 6.6e-35 120.0 0.1 2.3 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 GBG90983.1 - 7.6e-08 32.5 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 GBG90983.1 - 0.0016 18.8 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 GBG90983.1 - 0.073 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RPA43_OB PF17875.1 GBG90984.1 - 5.2 7.7 8.6 1.5 9.4 5.5 1.7 1 1 1 2 2 2 0 RPA43 OB domain in RNA Pol I RVT_1 PF00078.27 GBG90985.1 - 1.2e-21 77.3 0.1 1.7e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG90986.1 - 0.0037 16.8 0.1 0.12 11.8 0.0 2.8 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fungal_KA1 PF16797.5 GBG90986.1 - 0.043 13.5 0.1 0.043 13.5 0.1 2.3 2 0 0 2 2 2 0 Fungal kinase associated-1 domain JmjC PF02373.22 GBG90986.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase WD40 PF00400.32 GBG90987.1 - 2.6e-10 40.7 1.2 4.5e-05 24.1 0.2 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat DMPK_coil PF08826.10 GBG90987.1 - 0.0013 18.8 22.9 0.0046 17.1 8.6 5.6 3 2 3 6 6 6 2 DMPK coiled coil domain like ApoC-I PF04691.12 GBG90987.1 - 0.0025 17.7 12.0 0.34 10.9 1.5 3.0 2 0 0 2 2 2 2 Apolipoprotein C-I (ApoC-1) Cep57_CLD_2 PF14197.6 GBG90987.1 - 0.008 16.2 2.6 0.008 16.2 2.6 6.3 4 3 0 5 5 4 2 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 GBG90987.1 - 0.011 15.8 58.5 0.052 13.7 3.8 7.2 2 2 7 9 9 9 0 bZIP transcription factor CCDC92 PF14916.6 GBG90987.1 - 0.032 14.0 9.7 0.86 9.4 0.2 4.3 3 0 0 3 3 3 0 Coiled-coil domain of unknown function RNA_pol_Rpb6 PF01192.22 GBG90987.1 - 0.055 13.4 6.8 10 6.1 2.2 3.7 2 1 0 2 2 2 0 RNA polymerase Rpb6 DUF3802 PF12290.8 GBG90987.1 - 0.11 13.0 13.1 1 9.9 1.5 3.2 1 1 2 4 4 4 0 Protein of unknown function (DUF3802) Golgin_A5 PF09787.9 GBG90987.1 - 0.12 11.8 58.9 1.6 8.2 32.6 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4618 PF15397.6 GBG90987.1 - 2.3 7.6 51.4 1.1e+02 2.1 12.5 5.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) GAS PF13851.6 GBG90987.1 - 2.6 7.3 66.4 0.12 11.7 25.5 3.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lectin_N PF03954.14 GBG90987.1 - 4.5 7.0 24.9 41 3.9 13.0 3.8 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain HALZ PF02183.18 GBG90987.1 - 5.5 7.3 24.3 9.9 6.5 0.4 5.8 5 1 1 6 6 5 0 Homeobox associated leucine zipper ATG16 PF08614.11 GBG90987.1 - 8.6 6.5 64.5 2.9 8.1 12.2 4.4 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) WD40_alt PF14077.6 GBG90987.1 - 8.9 6.3 29.7 10 6.1 0.1 7.3 7 0 0 7 7 7 0 Alternative WD40 repeat motif Pkinase PF00069.25 GBG90988.1 - 3.2e-24 85.7 0.0 4.2e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG90988.1 - 6.2e-22 78.1 0.0 7.9e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_6 PF12913.7 GBG90988.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) RVT_1 PF00078.27 GBG90989.1 - 2.5e-22 79.5 0.1 5e-20 72.0 0.1 2.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG90989.1 - 0.034 13.9 0.0 0.098 12.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease CENP-K PF11802.8 GBG90989.1 - 0.1 12.1 2.3 0.26 10.8 2.3 1.6 1 1 0 1 1 1 0 Centromere-associated protein K TMEM247 PF15444.6 GBG90989.1 - 0.5 10.4 0.1 0.5 10.4 0.1 1.8 1 1 1 2 2 2 0 Transmembrane protein 247 Integrase_H2C2 PF17921.1 GBG90990.1 - 2.7e-07 30.6 0.0 6.7e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG90990.1 - 0.0011 19.5 0.0 0.004 17.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90990.1 - 0.0012 19.3 1.9 0.003 18.1 0.2 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG90990.1 - 0.096 12.9 12.3 0.013 15.7 2.9 2.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 PriC PF07445.12 GBG90990.1 - 0.15 12.0 5.4 1.1 9.2 0.8 2.7 3 0 0 3 3 3 0 Primosomal replication protein priC Pkinase PF00069.25 GBG90991.1 - 7.1e-25 87.9 0.0 7.1e-25 87.9 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG90991.1 - 5.1e-21 75.1 0.0 1.2e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG90991.1 - 3.4e-17 62.5 7.6 2.9e-06 27.9 0.2 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG90991.1 - 0.00056 20.1 0.6 0.22 11.9 0.1 3.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Lectin_N PF03954.14 GBG90991.1 - 0.21 11.4 3.2 0.21 11.3 2.0 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain CLZ PF16526.5 GBG90991.1 - 4 7.9 23.3 0.4 11.1 5.0 3.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RVT_1 PF00078.27 GBG90992.1 - 9.9e-28 97.2 0.1 1.5e-27 96.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90992.1 - 2.5e-23 82.0 0.0 5.4e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90992.1 - 7e-17 61.3 0.1 2e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90992.1 - 9.7e-16 58.0 0.0 2.2e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG90992.1 - 3.4e-09 36.9 0.0 9.2e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG90992.1 - 5.5e-08 32.7 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90992.1 - 7.8e-06 26.4 0.0 2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90992.1 - 7.7e-05 23.2 0.0 0.00018 22.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG90992.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CENP-F_leu_zip PF10473.9 GBG90992.1 - 0.2 11.7 2.5 0.66 10.0 1.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 2OG-FeII_Oxy_2 PF13532.6 GBG90993.1 - 0.006 16.8 0.3 0.018 15.2 0.3 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3987 PF13148.6 GBG90993.1 - 0.009 15.1 5.2 0.009 15.1 5.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) DUF4790 PF16037.5 GBG90993.1 - 0.1 13.1 2.3 0.37 11.3 2.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4790) Phage_lysozyme PF00959.19 GBG90993.1 - 0.43 11.1 0.0 0.43 11.1 0.0 2.9 5 0 0 5 5 5 0 Phage lysozyme RT_RNaseH PF17917.1 GBG90995.1 - 1.4e-28 99.2 0.4 1.4e-27 96.0 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG90995.1 - 1.3e-27 95.7 0.1 1e-26 92.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90995.1 - 5.3e-19 68.1 0.6 1.2e-18 67.0 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG90995.1 - 3.7e-16 59.4 0.0 1e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG90995.1 - 1.8e-11 44.0 0.0 4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG90995.1 - 4.6e-08 32.9 0.0 9.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG90995.1 - 1.2e-06 29.1 0.0 2.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG90995.1 - 0.00023 21.6 0.0 0.00076 20.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG90995.1 - 0.0011 19.1 0.1 0.0034 17.6 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger NdhM PF10664.9 GBG90995.1 - 0.038 14.3 0.2 0.25 11.6 0.0 2.5 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M DUF1758 PF05585.12 GBG90995.1 - 0.046 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) FAM60A PF15396.6 GBG90995.1 - 1.3 9.0 4.4 3.1 7.8 4.4 1.5 1 0 0 1 1 1 0 Protein Family FAM60A RVT_1 PF00078.27 GBG90996.1 - 8.5e-29 100.7 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG90996.1 - 7.5e-26 90.1 0.0 2.3e-25 88.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG90996.1 - 4.9e-17 61.8 0.3 9.8e-17 60.8 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG90996.1 - 5.4e-13 49.1 0.0 1.5e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG90996.1 - 1.5e-10 41.0 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.26 GBG90996.1 - 6.6e-10 39.2 0.2 1.8e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG90996.1 - 0.0012 19.5 0.0 0.0036 17.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG90996.1 - 0.021 15.1 0.9 1.7 9.0 0.0 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 GBG90996.1 - 0.023 15.2 0.0 0.098 13.2 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF4407 PF14362.6 GBG90996.1 - 1.1 8.5 6.7 2.7 7.3 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EzrA PF06160.12 GBG90996.1 - 1.2 7.2 9.5 2.2 6.4 9.5 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 GBG90996.1 - 2.2 7.8 8.2 4.9 6.6 8.2 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Retrotrans_gag PF03732.17 GBG90997.1 - 0.0027 17.9 1.6 0.017 15.3 0.0 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein Presenilin PF01080.17 GBG90997.1 - 0.025 13.3 2.6 0.045 12.5 2.6 1.3 1 0 0 1 1 1 0 Presenilin gpUL132 PF11359.8 GBG90997.1 - 0.097 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 p450 PF00067.22 GBG90998.1 - 0.00046 19.0 0.2 0.0063 15.3 0.1 2.2 2 1 0 2 2 2 2 Cytochrome P450 DUF287 PF03384.14 GBG90999.1 - 0.12 12.8 0.9 0.28 11.6 0.9 1.6 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 zf-CCHC PF00098.23 GBG91000.1 - 0.00013 21.9 2.8 0.0002 21.3 2.8 1.3 1 0 0 1 1 1 1 Zinc knuckle VIR_N PF15912.5 GBG91000.1 - 0.25 10.9 3.9 0.55 9.8 3.9 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal PRIMA1 PF16101.5 GBG91000.1 - 0.51 10.4 10.3 1.1 9.4 10.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 UPF1_Zn_bind PF09416.10 GBG91000.1 - 1.1 9.2 3.7 1.7 8.6 0.1 2.4 2 1 0 2 2 2 0 RNA helicase (UPF2 interacting domain) BST2 PF16716.5 GBG91000.1 - 6.6 7.4 17.0 19 5.9 0.5 3.5 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 ANF_receptor PF01094.28 GBG91001.1 - 0.0091 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region NCA2 PF08637.10 GBG91003.1 - 8.4e-55 186.0 0.1 1.2e-54 185.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 SpoVAB PF13782.6 GBG91003.1 - 0.022 15.0 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 Stage V sporulation protein AB ELFV_dehydrog_N PF02812.18 GBG91003.1 - 0.073 13.0 0.0 0.073 13.0 0.0 2.2 3 0 0 3 3 3 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain zf-CCHC PF00098.23 GBG91006.1 - 4.9e-05 23.2 3.2 9.3e-05 22.3 3.2 1.5 1 0 0 1 1 1 1 Zinc knuckle CAP_N PF01213.19 GBG91006.1 - 0.045 13.2 12.6 0.12 11.9 12.6 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-CCHC_4 PF14392.6 GBG91006.1 - 0.072 12.8 2.0 0.15 11.8 2.0 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG91006.1 - 0.095 12.6 0.3 0.38 10.6 0.3 2.0 1 0 0 1 1 1 0 Zinc knuckle Fzo_mitofusin PF04799.13 GBG91006.1 - 5.3 6.6 21.4 0.82 9.2 1.1 3.4 2 1 1 3 3 3 0 fzo-like conserved region zf-CCHC PF00098.23 GBG91008.1 - 0.021 14.9 1.9 0.032 14.3 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG91008.1 - 0.054 13.2 0.2 0.096 12.4 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like gag-asp_proteas PF13975.6 GBG91009.1 - 2.9e-06 27.8 0.1 5.5e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG91009.1 - 9.8e-05 22.2 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG91009.1 - 0.0005 20.7 0.1 0.0011 19.6 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG91009.1 - 0.00076 19.4 11.0 0.16 12.1 1.9 2.5 2 0 0 2 2 2 2 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG91009.1 - 0.0026 17.4 0.5 3.1 7.6 0.1 2.5 2 0 0 2 2 2 2 Topoisomerase I zinc-ribbon-like PBP_sp32 PF07222.12 GBG91009.1 - 0.0027 17.2 0.0 3.3 7.1 0.0 2.5 3 0 0 3 3 3 2 Proacrosin binding protein sp32 RVP_2 PF08284.11 GBG91009.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease HemN_C PF06969.16 GBG91009.1 - 0.06 13.4 0.0 19 5.4 0.0 2.4 2 0 0 2 2 2 0 HemN C-terminal domain Molybdopterin_N PF18364.1 GBG91009.1 - 0.12 12.4 0.2 30 4.7 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain RBR PF17208.3 GBG91009.1 - 0.21 12.3 1.1 34 5.2 0.1 2.5 2 0 0 2 2 2 0 RNA binding Region ATE_N PF04376.13 GBG91009.1 - 1 9.8 0.0 1 9.8 0.0 3.5 4 0 0 4 4 4 0 Arginine-tRNA-protein transferase, N terminus MAP17 PF15807.5 GBG91010.1 - 0.61 10.3 3.5 0.8 9.9 0.0 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 gag-asp_proteas PF13975.6 GBG91012.1 - 1.6e-05 25.3 0.0 6.4e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG91012.1 - 0.00026 20.7 0.1 0.00051 19.8 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG91012.1 - 0.00077 19.2 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91012.1 - 0.018 15.7 0.0 0.099 13.3 0.0 2.3 1 0 0 1 1 1 0 Aspartyl protease Serglycin PF04360.12 GBG91013.1 - 0.0013 18.7 0.0 0.0042 17.0 0.0 1.8 1 0 0 1 1 1 1 Serglycin Paramecium_SA PF01508.16 GBG91013.1 - 0.051 14.0 8.2 1.2 9.6 0.5 2.7 2 0 0 2 2 2 0 Paramecium surface antigen domain Glyco_transf_5 PF08323.11 GBG91014.1 - 4.8e-30 105.0 0.0 8.6e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG91014.1 - 7.8e-09 35.3 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 FMN_red PF03358.15 GBG91014.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Glyco_transf_5 PF08323.11 GBG91015.1 - 4e-17 62.7 0.4 3.6e-08 33.4 0.4 2.2 1 1 1 2 2 2 2 Starch synthase catalytic domain RT_RNaseH_2 PF17919.1 GBG91016.1 - 1.2e-25 89.4 0.0 2.3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91016.1 - 2.1e-23 82.6 0.0 3.8e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91016.1 - 1.4e-14 54.2 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VPS13_C PF16909.5 GBG91017.1 - 8.7e-09 35.4 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal RVT_1 PF00078.27 GBG91018.1 - 1.7e-30 106.2 0.1 2.3e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91018.1 - 7.5e-20 70.8 0.0 2.9e-19 69.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91018.1 - 7e-10 39.1 0.0 3.1e-09 37.1 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG91018.1 - 6.4e-08 33.1 0.0 1.3e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91018.1 - 6.1e-07 29.9 0.0 1.3e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG91018.1 - 5.9e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG91018.1 - 0.00051 19.8 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG91019.1 - 2.5e-28 99.1 0.1 3.9e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91019.1 - 8.2e-20 70.7 0.0 2.2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91019.1 - 8.9e-08 32.4 0.0 3.6e-07 30.4 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG91019.1 - 8.9e-07 28.8 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91019.1 - 1.1e-05 25.9 0.0 6e-05 23.6 0.0 2.3 1 0 0 1 1 1 1 Aspartyl protease HALZ PF02183.18 GBG91019.1 - 8.4e-05 22.7 8.7 0.088 13.1 1.2 2.7 2 0 0 2 2 2 2 Homeobox associated leucine zipper Asp_protease PF09668.10 GBG91019.1 - 8.9e-05 22.3 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91019.1 - 0.00013 22.5 0.0 0.00054 20.5 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RP-C_C PF11800.8 GBG91019.1 - 0.00019 21.6 0.1 1.1 9.4 0.0 2.8 2 0 0 2 2 2 2 Replication protein C C-terminal region CCD48 PF15799.5 GBG91019.1 - 0.00048 18.6 8.7 0.079 11.3 1.2 2.2 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 48 YabA PF06156.13 GBG91019.1 - 0.0012 19.5 1.3 4.7 7.9 0.0 3.3 3 0 0 3 3 3 2 Initiation control protein YabA DUF4988 PF16378.5 GBG91019.1 - 0.0014 18.3 1.8 1.4 8.5 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function bZIP_1 PF00170.21 GBG91019.1 - 0.01 15.9 16.5 0.17 12.0 1.6 3.5 3 0 0 3 3 3 0 bZIP transcription factor DivIC PF04977.15 GBG91019.1 - 0.011 15.5 10.3 0.74 9.6 1.7 2.7 2 0 0 2 2 2 0 Septum formation initiator Pil1 PF13805.6 GBG91019.1 - 0.016 14.8 0.1 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Eisosome component PIL1 Filament PF00038.21 GBG91019.1 - 0.018 14.6 2.0 5.4 6.5 0.1 2.8 3 0 0 3 3 2 0 Intermediate filament protein ZapB PF06005.12 GBG91019.1 - 0.019 15.4 13.9 1.2 9.6 3.1 3.0 2 0 0 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 GBG91019.1 - 0.037 14.4 1.4 12 6.3 0.1 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF1515 PF07439.11 GBG91019.1 - 0.041 13.9 0.6 17 5.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) TSC22 PF01166.18 GBG91019.1 - 0.068 13.5 10.6 3.4 8.1 1.2 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family Wtap PF17098.5 GBG91019.1 - 0.096 12.6 7.6 2 8.3 0.2 2.8 3 0 0 3 3 2 0 WTAP/Mum2p family DUF4543 PF15076.6 GBG91019.1 - 0.11 12.6 0.1 42 4.4 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) DUF5481 PF17578.2 GBG91019.1 - 0.12 12.8 1.8 19 5.7 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5481) DMPK_coil PF08826.10 GBG91019.1 - 0.13 12.4 13.7 0.47 10.6 0.7 2.9 3 0 0 3 3 2 0 DMPK coiled coil domain like XhlA PF10779.9 GBG91019.1 - 0.19 11.9 8.3 3.4 7.9 0.2 3.1 3 0 0 3 3 2 0 Haemolysin XhlA bZIP_2 PF07716.15 GBG91019.1 - 0.25 11.4 23.5 0.34 11.0 3.3 3.9 3 0 0 3 3 3 0 Basic region leucine zipper BST2 PF16716.5 GBG91019.1 - 0.71 10.5 5.4 21 5.8 0.5 2.8 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 FlaC_arch PF05377.11 GBG91019.1 - 0.91 10.0 13.7 2.6 8.5 0.9 3.4 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF5595 PF18077.1 GBG91019.1 - 1.1 9.4 4.6 29 4.8 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) YscO PF07321.12 GBG91019.1 - 1.5 8.8 19.9 5.9 6.8 6.0 2.7 2 0 0 2 2 2 0 Type III secretion protein YscO BRE1 PF08647.11 GBG91019.1 - 1.6 8.9 7.0 12 6.0 0.1 3.0 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase Spc24 PF08286.11 GBG91019.1 - 1.6 9.0 5.3 22 5.3 0.1 2.9 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 ADIP PF11559.8 GBG91019.1 - 1.9 8.5 6.1 25 4.9 0.6 3.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 GBG91019.1 - 2.6 8.4 18.6 0.79 10.0 1.2 3.6 4 0 0 4 4 2 0 ABC transporter C-terminal domain GIT_CC PF16559.5 GBG91019.1 - 3.2 7.7 18.6 2.3 8.1 2.4 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4618 PF15397.6 GBG91019.1 - 5.7 6.3 9.4 6.9 6.0 0.4 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4618) Herpes_capsid PF06112.11 GBG91019.1 - 7.1 6.7 24.7 2.3 8.3 2.8 3.4 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein HAP1_N PF04849.13 GBG91019.1 - 7.7 5.6 12.5 5.7 6.1 0.5 3.1 3 0 0 3 3 3 0 HAP1 N-terminal conserved region RVT_1 PF00078.27 GBG91020.1 - 2.1e-33 115.7 0.1 3.3e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91020.1 - 8.7e-30 103.1 0.1 1.7e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91020.1 - 1.1e-27 96.0 0.0 2.4e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91020.1 - 5.3e-17 61.7 1.6 1.2e-16 60.6 1.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_GPO PF05929.11 GBG91020.1 - 0.085 12.5 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-H2C2 PF09337.10 GBG91020.1 - 0.14 12.4 0.4 0.4 10.9 0.4 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG91021.1 - 3.2e-27 95.5 0.0 6.8e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91021.1 - 3.8e-26 91.0 0.0 8.6e-26 89.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91021.1 - 4.9e-25 87.8 0.0 1e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91021.1 - 1.6e-16 60.1 0.4 3.7e-16 59.0 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91021.1 - 2.4e-09 37.4 0.0 6.6e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG91021.1 - 0.00061 20.0 0.0 0.0034 17.6 0.0 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein PCEMA1 PF07418.11 GBG91022.1 - 4.1 6.8 12.8 7 6.1 12.8 1.3 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 RT_RNaseH_2 PF17919.1 GBG91023.1 - 3.8e-28 97.4 0.1 7.6e-28 96.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91023.1 - 1.1e-27 97.0 0.1 2.7e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91023.1 - 3.3e-24 85.2 0.1 6e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91023.1 - 0.091 12.9 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG91024.1 - 6e-21 74.7 0.1 2.1e-20 73.0 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91024.1 - 1.8e-19 69.6 0.6 4.6e-19 68.3 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG91024.1 - 3.1e-11 43.2 0.0 8.6e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG91024.1 - 1.5e-06 28.0 0.0 3.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91024.1 - 1.3e-05 25.7 0.0 3.3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG91024.1 - 6.6e-05 23.1 0.2 0.00033 20.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG91024.1 - 0.00052 20.5 0.0 0.0022 18.5 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG91024.1 - 0.001 19.2 0.1 0.0024 18.1 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG91024.1 - 0.025 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG91024.1 - 0.032 14.0 0.0 0.86 9.4 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease 2OG-FeII_Oxy_2 PF13532.6 GBG91024.1 - 0.063 13.5 0.5 0.24 11.6 0.5 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Es2 PF09751.9 GBG91024.1 - 2.1 8.0 16.7 3.3 7.4 16.7 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 RVT_1 PF00078.27 GBG91025.1 - 1.2e-28 100.2 0.2 2e-28 99.4 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91025.1 - 2.9e-22 78.6 0.0 6.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91025.1 - 8.7e-19 67.4 0.5 2.5e-18 65.9 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91025.1 - 6e-12 45.8 0.1 2.6e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG91025.1 - 1.7e-10 41.1 0.0 5.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG91025.1 - 0.0042 17.3 0.1 0.021 15.0 0.1 2.3 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 GBG91026.1 - 0.0002 21.3 1.1 0.00041 20.3 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle HflK_N PF12221.8 GBG91026.1 - 0.096 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial membrane protein N terminal TbpB_B_D PF01298.18 GBG91027.1 - 0.067 13.6 0.8 0.16 12.3 0.4 1.9 2 0 0 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Nop14 PF04147.12 GBG91027.1 - 0.14 10.4 17.7 0.19 9.9 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG91027.1 - 0.66 9.3 13.5 1 8.6 13.5 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG91027.1 - 2 7.7 18.6 3.3 7.0 18.6 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG91027.1 - 4.8 5.3 15.7 7.8 4.6 15.7 1.2 1 0 0 1 1 1 0 CDC45-like protein N6_N4_Mtase PF01555.18 GBG91028.1 - 1.8e-07 31.2 0.7 2.8e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 DNA methylase SDA1 PF05285.12 GBG91028.1 - 0.00079 19.0 13.4 0.0019 17.7 13.4 1.6 1 0 0 1 1 1 1 SDA1 DDE_Tnp_4 PF13359.6 GBG91030.1 - 8.8e-27 93.7 0.0 1.3e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91030.1 - 5.9e-12 45.6 0.0 8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91030.1 - 0.071 12.8 0.0 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain DUF4242 PF14026.6 GBG91031.1 - 0.057 13.6 0.6 0.14 12.4 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4242) Myb_DNA-bind_4 PF13837.6 GBG91032.1 - 7.2e-07 29.5 4.4 1.3e-06 28.7 4.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91032.1 - 0.011 16.1 1.4 0.028 14.7 1.4 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG91032.1 - 0.15 12.2 0.6 0.28 11.3 0.6 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG91032.1 - 1.1 9.6 7.5 0.042 14.0 1.1 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG91033.1 - 4.6e-24 84.9 0.0 6.4e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91033.1 - 1.4e-11 44.4 0.0 2.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91033.1 - 0.00086 19.0 0.7 0.0092 15.6 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain Integrase_H2C2 PF17921.1 GBG91034.1 - 4e-13 49.2 0.1 9.1e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91034.1 - 2.6e-06 27.6 0.0 4.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91034.1 - 0.00012 22.2 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger PA26 PF04636.13 GBG91035.1 - 0.01 14.8 7.3 0.012 14.6 7.3 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF5401 PF17380.2 GBG91035.1 - 1.5 6.8 23.4 2 6.4 23.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Presenilin PF01080.17 GBG91035.1 - 1.5 7.5 6.5 1.7 7.3 6.5 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 GBG91035.1 - 3.6 5.6 6.9 4.1 5.4 6.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPAT_C PF15712.5 GBG91035.1 - 4 6.0 11.1 5.1 5.6 11.1 1.1 1 0 0 1 1 1 0 NPAT C terminus FAM60A PF15396.6 GBG91035.1 - 5.8 6.8 8.6 7.7 6.5 8.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 GBG91035.1 - 6.6 5.4 8.5 8.7 5.1 8.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter ABC_tran PF00005.27 GBG91036.1 - 3.4e-26 92.4 0.1 6.3e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG91036.1 - 1.3e-06 28.5 0.6 0.018 14.9 0.0 2.7 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GBG91036.1 - 7.3e-05 22.7 0.5 0.00014 21.8 0.5 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 GBG91036.1 - 0.00018 21.2 0.1 0.00039 20.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 GBG91036.1 - 0.001 18.6 0.1 0.01 15.3 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GBG91036.1 - 0.0019 18.5 0.1 0.0047 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG91036.1 - 0.0031 17.9 0.0 0.0062 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GBG91036.1 - 0.0043 16.8 0.2 0.0083 15.9 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 GBG91036.1 - 0.0081 16.7 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 GBG91036.1 - 0.0089 15.4 0.2 0.15 11.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain cobW PF02492.19 GBG91036.1 - 0.0094 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GBG91036.1 - 0.011 15.5 1.6 0.023 14.4 1.6 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GBG91036.1 - 0.021 15.0 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GBG91036.1 - 0.038 13.7 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 GBG91036.1 - 0.042 13.3 0.2 0.068 12.6 0.2 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_18 PF13238.6 GBG91036.1 - 0.075 13.6 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GBG91036.1 - 0.1 13.0 0.5 0.2 12.1 0.5 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GBG91036.1 - 0.12 12.3 0.2 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 GBG91036.1 - 0.13 12.4 0.8 0.3 11.2 0.8 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3037 PF11236.8 GBG91036.1 - 0.13 12.7 0.4 10 6.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) TsaE PF02367.17 GBG91036.1 - 0.17 11.9 0.3 0.63 10.0 0.2 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GBG91036.1 - 0.83 9.9 3.1 0.82 9.9 0.6 2.0 2 0 0 2 2 2 0 AAA domain RVT_1 PF00078.27 GBG91038.1 - 1.4e-29 103.2 0.1 2.2e-29 102.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91038.1 - 2.5e-25 88.8 0.2 5e-25 87.8 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91038.1 - 3.1e-18 65.7 0.0 6.8e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91038.1 - 1.7e-11 44.0 0.0 4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC_3 PF13917.6 GBG91038.1 - 0.026 14.5 1.6 0.055 13.4 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3863 PF12979.7 GBG91038.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) CpXC PF14353.6 GBG91038.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 CpXC protein Retrotrans_gag PF03732.17 GBG91039.1 - 0.017 15.4 3.6 1.6 9.0 0.0 3.3 3 0 0 3 3 3 0 Retrotransposon gag protein BRD4_CDT PF17105.5 GBG91039.1 - 0.035 13.7 3.7 0.36 10.5 0.2 3.0 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 DUF4798 PF16055.5 GBG91039.1 - 0.17 12.1 3.9 0.34 11.2 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) Nop53 PF07767.11 GBG91039.1 - 0.3 10.4 10.6 0.6 9.4 10.6 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF659 PF04937.15 GBG91041.1 - 7.1e-21 74.7 0.2 1.1e-20 74.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CDC45 PF02724.14 GBG91041.1 - 1.1 7.5 3.2 2.1 6.6 3.2 1.4 1 0 0 1 1 1 0 CDC45-like protein ubiquitin PF00240.23 GBG91045.1 - 1.1e-12 47.5 0.2 1.7e-12 46.9 0.2 1.3 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GBG91045.1 - 0.00057 19.7 0.1 0.00092 19.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GBG91045.1 - 0.0077 16.7 0.1 0.014 15.9 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain Hep_59 PF07052.11 GBG91046.1 - 0.044 14.5 11.5 0.064 14.0 10.6 1.8 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 zf-CCHC PF00098.23 GBG91046.1 - 0.062 13.4 1.0 0.13 12.4 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG91046.1 - 0.14 12.0 1.2 0.26 11.2 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2058 PF09831.9 GBG91046.1 - 0.34 11.0 17.4 0.7 10.0 17.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Borrelia_P83 PF05262.11 GBG91046.1 - 0.8 8.1 15.1 1.1 7.6 15.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1943 PF09172.11 GBG91046.1 - 1.9 7.7 4.5 2.9 7.1 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Prominin PF05478.11 GBG91046.1 - 2 6.3 4.1 2.6 5.9 4.1 1.1 1 0 0 1 1 1 0 Prominin HAP2-GCS1 PF10699.9 GBG91047.1 - 0.033 14.2 1.8 0.6 10.1 0.3 3.0 2 0 0 2 2 2 0 Male gamete fusion factor Nop14 PF04147.12 GBG91048.1 - 0.011 14.0 7.2 0.011 14.0 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG91048.1 - 0.1 12.9 11.3 0.13 12.5 11.3 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 GBG91048.1 - 0.17 11.3 11.1 0.2 11.0 11.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG91048.1 - 0.28 9.4 10.1 0.33 9.2 10.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-bind_4 PF13837.6 GBG91049.1 - 7.3e-05 23.1 2.6 0.00012 22.4 2.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain VPS9 PF02204.18 GBG91050.1 - 1.6e-14 54.0 0.0 3.7e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 GBG91050.1 - 4.9e-05 23.8 0.1 0.002 18.6 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 GBG91050.1 - 0.026 14.9 0.0 0.074 13.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Serglycin PF04360.12 GBG91050.1 - 0.092 12.7 0.7 0.19 11.7 0.7 1.4 1 0 0 1 1 1 0 Serglycin DUF2076 PF09849.9 GBG91051.1 - 3 7.8 11.4 4.5 7.2 11.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) HisKA_4TM PF16926.5 GBG91052.1 - 0.05 13.2 0.2 0.081 12.5 0.2 1.3 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase Glycolytic PF00274.19 GBG91053.1 - 4.6e-172 571.5 0.1 5.2e-172 571.4 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Caldesmon PF02029.15 GBG91054.1 - 0.2 10.4 50.4 0.22 10.2 50.4 1.0 1 0 0 1 1 1 0 Caldesmon Pox_Ag35 PF03286.14 GBG91054.1 - 0.46 10.3 40.5 0.86 9.4 10.7 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RPN2_C PF18004.1 GBG91054.1 - 9.5 6.1 46.8 2.9 7.8 14.2 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CobT PF06213.12 GBG91055.1 - 0.016 14.6 15.3 0.017 14.6 15.3 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 GBG91055.1 - 0.025 13.8 8.7 0.025 13.8 8.7 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CPSF100_C PF13299.6 GBG91055.1 - 0.029 14.5 3.1 0.032 14.4 3.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Afi1 PF07792.12 GBG91055.1 - 0.031 14.7 5.5 0.032 14.7 5.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SpoIIP PF07454.11 GBG91055.1 - 0.032 13.7 3.8 0.031 13.7 3.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.12 GBG91055.1 - 0.06 12.3 2.5 0.059 12.3 2.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4366 PF14283.6 GBG91055.1 - 0.064 13.3 4.3 0.085 12.9 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RAB3GAP2_C PF14656.6 GBG91055.1 - 0.071 11.3 4.2 0.075 11.2 4.2 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Nop14 PF04147.12 GBG91055.1 - 0.078 11.2 20.0 0.083 11.1 20.0 1.0 1 0 0 1 1 1 0 Nop14-like family ORC_WH_C PF18137.1 GBG91055.1 - 0.084 12.9 7.6 0.093 12.8 7.6 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal AIF_C PF14721.6 GBG91055.1 - 0.097 13.0 1.1 0.097 13.0 1.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DARPP-32 PF05395.12 GBG91055.1 - 0.1 12.8 12.2 0.12 12.6 12.2 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Tim54 PF11711.8 GBG91055.1 - 0.11 11.2 7.3 0.12 11.1 7.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PTPRCAP PF15713.5 GBG91055.1 - 0.12 12.7 19.7 0.16 12.3 19.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Connexin PF00029.19 GBG91055.1 - 0.13 12.0 3.1 0.14 11.9 3.1 1.1 1 0 0 1 1 1 0 Connexin Sigma70_ner PF04546.13 GBG91055.1 - 0.14 12.1 13.2 0.16 11.9 13.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region BSP_II PF05432.11 GBG91055.1 - 0.14 11.9 19.5 0.19 11.4 19.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4820 PF16091.5 GBG91055.1 - 0.23 10.8 3.9 0.24 10.7 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NPR3 PF03666.13 GBG91055.1 - 0.24 10.2 4.3 0.28 9.9 4.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MIF4G_like_2 PF09090.11 GBG91055.1 - 0.3 10.5 4.4 0.31 10.5 4.4 1.0 1 0 0 1 1 1 0 MIF4G like DUF2428 PF10350.9 GBG91055.1 - 0.32 10.2 2.9 0.32 10.2 2.9 1.1 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) SDA1 PF05285.12 GBG91055.1 - 0.46 9.9 23.1 0.51 9.7 23.1 1.0 1 0 0 1 1 1 0 SDA1 V_ATPase_I PF01496.19 GBG91055.1 - 0.46 8.3 5.6 0.46 8.3 5.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 GBG91055.1 - 0.61 8.8 3.3 0.64 8.7 3.3 1.0 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 GBG91055.1 - 0.62 10.5 6.2 0.73 10.2 6.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 PPL5 PF18168.1 GBG91055.1 - 0.65 9.2 4.6 0.65 9.2 4.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SURF2 PF05477.11 GBG91055.1 - 0.66 9.6 9.9 0.81 9.3 9.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RR_TM4-6 PF06459.12 GBG91055.1 - 0.8 9.5 11.1 0.88 9.3 11.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5523 PF17661.1 GBG91055.1 - 0.81 9.3 15.8 0.91 9.2 15.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Zip PF02535.22 GBG91055.1 - 0.84 8.8 6.2 0.9 8.7 6.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RRN3 PF05327.11 GBG91055.1 - 0.84 8.1 11.5 0.8 8.2 11.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4746 PF15928.5 GBG91055.1 - 0.98 8.8 16.1 1.1 8.7 16.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2722 PF10846.8 GBG91055.1 - 0.98 8.3 5.8 0.99 8.3 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Mpp10 PF04006.12 GBG91055.1 - 1.1 7.7 21.2 1.2 7.5 21.2 1.0 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.12 GBG91055.1 - 1.6 8.0 21.9 1.9 7.8 21.9 1.1 1 0 0 1 1 1 0 NOA36 protein TSA PF03249.13 GBG91055.1 - 2.1 7.1 4.2 2 7.1 4.2 1.0 1 0 0 1 1 1 0 Type specific antigen MAP17 PF15807.5 GBG91055.1 - 2.1 8.6 9.0 2.5 8.4 9.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RPA43_OB PF17875.1 GBG91055.1 - 2.8 8.6 9.4 3.8 8.1 9.4 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I SspB PF04386.13 GBG91055.1 - 3.7 7.4 9.1 4.1 7.3 9.1 1.1 1 0 0 1 1 1 0 Stringent starvation protein B DUF4637 PF15470.6 GBG91055.1 - 3.8 7.2 25.3 5.2 6.8 25.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.14 GBG91055.1 - 5.8 6.7 16.0 7.7 6.2 16.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Vfa1 PF08432.10 GBG91055.1 - 6.6 7.0 15.6 8 6.7 15.6 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 GBG91055.1 - 7.2 6.5 17.8 8.9 6.2 17.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 GBG91055.1 - 7.5 4.7 18.6 8.5 4.5 18.6 1.0 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.18 GBG91055.1 - 7.6 5.3 17.7 8.6 5.1 17.7 1.0 1 0 0 1 1 1 0 Hsp90 protein LINES_C PF14695.6 GBG91056.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.7 1 0 0 1 1 1 0 Lines C-terminus CAP_N PF01213.19 GBG91057.1 - 0.023 14.2 4.4 0.034 13.6 4.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal R3H PF01424.22 GBG91057.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 R3H domain Mito_fiss_reg PF05308.11 GBG91057.1 - 0.35 10.9 1.5 0.54 10.3 1.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 GBG91057.1 - 0.67 10.0 6.9 1.3 9.1 6.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Myb_DNA-bind_4 PF13837.6 GBG91058.1 - 1.7e-07 31.5 0.4 2.6e-07 30.9 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91058.1 - 1.9e-05 24.9 0.8 3.1e-05 24.2 0.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG91058.1 - 0.0075 16.4 1.0 0.017 15.3 0.7 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG91058.1 - 0.24 11.5 2.7 0.74 9.9 1.9 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG91059.1 - 5.6e-28 96.9 0.0 9.5e-28 96.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91059.1 - 1.1e-24 86.7 0.0 3.1e-24 85.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91059.1 - 9.8e-06 25.2 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG91059.1 - 4.2 5.4 13.0 5.4 5.1 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG91059.1 - 5.3 6.4 12.5 7.3 5.9 12.5 1.1 1 0 0 1 1 1 0 SDA1 Arm PF00514.23 GBG91060.1 - 0.0029 17.6 1.6 1.8 8.7 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF2569 PF10754.9 GBG91061.1 - 0.0022 18.4 6.1 0.0051 17.2 6.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2569) CAP_N PF01213.19 GBG91061.1 - 0.15 11.5 6.1 0.3 10.5 6.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GBG91061.1 - 0.66 10.0 19.4 0.064 13.3 8.8 2.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 GBG91061.1 - 1.2 9.2 3.2 2.3 8.2 3.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator RVT_1 PF00078.27 GBG91063.1 - 9.7e-25 87.4 0.0 1.5e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SGL PF08450.12 GBG91064.1 - 0.031 13.8 0.0 2.6 7.6 0.0 2.5 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region CCDC53 PF10152.9 GBG91064.1 - 0.78 10.2 2.8 3.1 8.2 0.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex VPS28 PF03997.12 GBG91065.1 - 1.8e-68 229.9 0.0 2.1e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein DUF4969 PF16339.5 GBG91066.1 - 0.38 11.1 1.0 0.98 9.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) RT_RNaseH_2 PF17919.1 GBG91067.1 - 2.4e-22 78.8 0.0 5.3e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91067.1 - 1.6e-21 76.6 0.0 6.1e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG91067.1 - 0.044 14.1 0.0 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease Asparaginase_2 PF01112.18 GBG91068.1 - 3.1e-68 230.1 2.9 3.1e-68 230.1 2.9 1.7 2 0 0 2 2 2 1 Asparaginase RT_RNaseH_2 PF17919.1 GBG91068.1 - 8.9e-18 64.2 0.0 1.5e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91068.1 - 2.2e-09 37.2 0.1 3.1e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91068.1 - 2.4e-06 27.8 0.0 4.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Fz PF01392.22 GBG91068.1 - 0.031 14.9 1.3 0.054 14.1 0.2 1.9 2 0 0 2 2 2 0 Fz domain DUF2116 PF09889.9 GBG91068.1 - 2.1 8.4 5.7 0.28 11.2 1.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) LAP1C PF05609.12 GBG91068.1 - 4.2 6.3 15.6 6.1 5.8 15.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cwf_Cwc_15 PF04889.12 GBG91068.1 - 5.6 6.6 26.1 9.7 5.8 26.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop53 PF07767.11 GBG91068.1 - 8.1 5.7 29.2 14 5.0 29.2 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Myb_DNA-bind_4 PF13837.6 GBG91069.1 - 7.7e-09 35.8 5.0 1.4e-08 35.0 5.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG91069.1 - 0.00054 20.2 1.6 0.0011 19.2 1.6 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91069.1 - 0.00087 19.6 2.3 0.0019 18.5 2.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG91069.1 - 0.0012 18.9 0.9 0.0023 18.0 0.9 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG91069.1 - 0.046 13.9 0.3 0.15 12.2 0.3 2.0 2 1 0 2 2 2 0 Myb-like DNA-binding domain TraI_2_C PF07515.11 GBG91069.1 - 0.079 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term zf-C3HC4 PF00097.25 GBG91071.1 - 1.9e-07 30.9 16.6 1.9e-07 30.9 16.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG91071.1 - 6.3e-06 25.9 15.4 6.3e-06 25.9 15.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG91071.1 - 0.0013 18.6 13.6 0.0013 18.6 13.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GBG91071.1 - 0.0037 17.3 15.9 0.0037 17.3 15.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Shisa PF13908.6 GBG91072.1 - 0.2 11.9 2.0 0.42 10.8 2.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SAPS PF04499.15 GBG91073.1 - 0.17 10.7 9.3 0.19 10.5 9.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FXR_C1 PF16096.5 GBG91073.1 - 2.8 8.2 18.6 7.4 6.9 0.2 4.3 4 0 0 4 4 4 0 Fragile X-related 1 protein C-terminal region 2 DUF659 PF04937.15 GBG91074.1 - 1.8e-30 105.8 0.3 2.8e-30 105.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pkinase_Tyr PF07714.17 GBG91077.1 - 6.6e-35 120.6 0.0 2.5e-34 118.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG91077.1 - 4.8e-32 111.4 0.0 6.8e-23 81.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain SKG6 PF08693.10 GBG91077.1 - 1.8 8.1 7.0 0.12 11.8 1.0 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TadF PF16964.5 GBG91078.1 - 3.8 7.2 5.7 7.6 6.3 5.7 1.5 1 0 0 1 1 1 0 Putative tight adherence pilin protein F TAXi_N PF14543.6 GBG91082.1 - 1.5e-17 64.4 6.2 2.1e-17 64.0 6.2 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GBG91082.1 - 2.3e-08 34.0 0.0 1.3e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 GBG91082.1 - 6.9e-08 32.3 0.6 2.4e-07 30.5 0.6 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Penaeidin PF05927.11 GBG91082.1 - 0.34 11.7 4.4 6.4 7.6 0.1 2.7 2 0 0 2 2 2 0 Penaeidin zf_CopZ PF18423.1 GBG91082.1 - 0.45 10.5 1.7 6.5 6.8 1.7 2.3 1 1 0 1 1 1 0 Zinc binding domain DDE_Tnp_4 PF13359.6 GBG91083.1 - 0.00016 21.4 0.3 0.00049 19.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease SURF2 PF05477.11 GBG91086.1 - 3.1 7.4 7.2 0.5 10.0 3.1 1.7 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Adeno_E3_15_3 PF03307.14 GBG91087.1 - 0.18 11.8 0.0 1 9.3 0.0 1.9 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region DUF2996 PF11210.8 GBG91089.1 - 2.9e-18 66.5 0.0 3.2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2996) Mito_carr PF00153.27 GBG91090.1 - 7.4e-26 89.9 7.0 2.6e-14 52.9 0.5 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Integrase_H2C2 PF17921.1 GBG91091.1 - 3.9e-14 52.5 0.1 7.1e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain SICA_C PF12879.7 GBG91091.1 - 0.00029 20.9 10.1 0.1 12.6 1.6 2.5 1 1 1 2 2 2 2 SICA C-terminal inner membrane domain zf-H2C2 PF09337.10 GBG91091.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 H2C2 zinc finger Tfb5 PF06331.12 GBG91092.1 - 9.6e-29 99.2 0.2 1.1e-28 99.0 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Mito_carr PF00153.27 GBG91093.1 - 5.8e-63 208.9 0.9 1.2e-20 73.2 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_61 PF03443.14 GBG91093.1 - 3e-44 151.4 0.1 4.4e-44 150.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CAP_N PF01213.19 GBG91093.1 - 1.3 8.4 5.3 2.7 7.4 5.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ank_2 PF12796.7 GBG91094.1 - 8.5e-51 170.5 6.3 4.2e-13 49.7 0.1 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GBG91094.1 - 2.1e-42 138.2 7.1 0.0013 19.1 0.0 10.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 GBG91094.1 - 2.1e-42 142.9 7.2 4.1e-12 46.4 0.1 7.2 4 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GBG91094.1 - 3.3e-38 129.2 14.2 9.9e-08 32.1 0.1 8.1 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 GBG91094.1 - 1.9e-37 126.0 26.8 4.9e-06 26.7 0.1 9.7 9 0 0 9 9 9 9 Ankyrin repeat DUF2052 PF09747.9 GBG91094.1 - 0.76 9.9 32.0 0.062 13.4 3.7 4.0 4 0 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 GBG91095.1 - 6.1e-05 22.6 27.7 7.1e-05 22.4 27.7 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GBG91095.1 - 0.89 8.8 39.7 1.2 8.4 39.7 1.1 1 0 0 1 1 1 0 BUD22 MA3 PF02847.17 GBG91097.1 - 3e-25 88.4 0.6 7.7e-25 87.1 0.6 1.8 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 GBG91097.1 - 2.9e-16 59.7 0.1 5.4e-15 55.6 0.0 2.7 3 0 0 3 3 3 1 MIF4G domain Myb_DNA-bind_4 PF13837.6 GBG91098.1 - 5.5e-07 29.9 0.1 1e-06 29.0 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG91098.1 - 0.098 12.9 1.2 0.34 11.2 1.2 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG91098.1 - 0.11 12.5 1.9 0.22 11.6 1.8 1.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Pex2_Pex12 PF04757.14 GBG91099.1 - 1.9e-35 122.5 0.0 5.2e-35 121.1 0.0 1.7 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region CDC45 PF02724.14 GBG91099.1 - 1e-05 24.1 0.1 1.4e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 CDC45-like protein zf-C3HC4_3 PF13920.6 GBG91099.1 - 4.4e-05 23.3 4.9 8.7e-05 22.3 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG91099.1 - 4.7e-05 23.1 6.3 4.7e-05 23.1 6.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SDA1 PF05285.12 GBG91099.1 - 5e-05 22.9 0.3 6.5e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 SDA1 DUF2722 PF10846.8 GBG91099.1 - 0.0089 15.0 6.5 0.018 14.0 6.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) PPP4R2 PF09184.11 GBG91099.1 - 0.019 14.6 2.0 0.027 14.1 2.0 1.3 1 0 0 1 1 1 0 PPP4R2 zf-RING_2 PF13639.6 GBG91099.1 - 0.02 15.2 5.7 0.05 13.9 5.7 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 GBG91099.1 - 0.51 10.3 5.3 1.2 9.1 5.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pox_Ag35 PF03286.14 GBG91099.1 - 0.98 9.2 6.3 1.6 8.5 6.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 GBG91099.1 - 1.1 9.0 15.0 1.9 8.1 15.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PRIMA1 PF16101.5 GBG91099.1 - 1.3 9.1 5.1 3.2 7.8 5.1 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-C3HC4_4 PF15227.6 GBG91099.1 - 1.4 9.2 9.2 3.3 7.9 9.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING BUD22 PF09073.10 GBG91099.1 - 2.4 7.4 10.5 4.1 6.6 10.5 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG91099.1 - 2.5 6.2 16.5 3.6 5.7 16.5 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 GBG91099.1 - 2.7 7.6 10.2 7.5 6.2 10.2 1.7 1 0 0 1 1 1 0 FAM176 family Utp14 PF04615.13 GBG91099.1 - 2.9 6.3 8.6 4.3 5.8 8.6 1.2 1 0 0 1 1 1 0 Utp14 protein RXT2_N PF08595.11 GBG91099.1 - 3.5 7.6 7.5 6 6.9 7.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 GBG91099.1 - 6.2 6.1 13.5 12 5.2 13.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT zf-RING_UBOX PF13445.6 GBG91099.1 - 9.7 6.3 14.7 0.53 10.3 9.3 1.7 2 0 0 2 2 1 0 RING-type zinc-finger DUF4360 PF14273.6 GBG91102.1 - 3.7e-15 56.3 0.0 4.9e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF659 PF04937.15 GBG91104.1 - 0.00013 21.9 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) EutK_C PF16365.5 GBG91106.1 - 3.6 7.7 7.4 7 6.8 0.2 3.4 3 0 0 3 3 3 0 Ethanolamine utilization protein EutK C-terminus CDC45 PF02724.14 GBG91107.1 - 0.054 11.8 8.3 0.06 11.6 8.3 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GBG91107.1 - 1.4 8.1 4.7 1.8 7.8 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein Trypan_PARP PF05887.11 GBG91107.1 - 2.3 8.2 9.9 3.2 7.7 9.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_phi PF04931.13 GBG91107.1 - 8.6 4.3 9.4 9.8 4.1 9.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Dimer_Tnp_hAT PF05699.14 GBG91108.1 - 0.0031 17.3 0.1 0.0061 16.3 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG91111.1 - 5.6e-28 98.0 0.1 9.1e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91111.1 - 0.0032 18.1 0.0 0.012 16.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease DUF4399 PF14347.6 GBG91111.1 - 0.076 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Lipase_3 PF01764.25 GBG91113.1 - 1.9e-19 69.9 0.0 3.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GBG91113.1 - 0.00034 21.3 0.1 0.0012 19.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GBG91113.1 - 0.047 12.9 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 GBG91113.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) WD40 PF00400.32 GBG91114.1 - 1.2e-26 92.4 7.7 9e-07 29.5 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF3337 PF11816.8 GBG91114.1 - 2.8e-08 33.8 0.0 2.3e-07 30.8 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3337) ANAPC4_WD40 PF12894.7 GBG91114.1 - 7.4e-05 23.0 0.0 0.17 12.2 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GBG91115.1 - 3e-17 62.7 1.9 9.8e-05 23.1 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF3337 PF11816.8 GBG91115.1 - 2.8e-08 33.8 0.0 2.3e-07 30.9 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3337) ANAPC4_WD40 PF12894.7 GBG91115.1 - 0.034 14.4 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF659 PF04937.15 GBG91116.1 - 1.5e-32 112.6 0.0 2.3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91116.1 - 1.4e-06 27.9 0.1 3.1e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UPF0561 PF10573.9 GBG91116.1 - 0.03 14.5 3.4 0.2 11.8 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 S6PP PF05116.13 GBG91117.1 - 4.1e-87 291.8 0.0 5.2e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase S6PP_C PF08472.10 GBG91117.1 - 3.4e-18 65.8 0.0 6.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Sucrose-6-phosphate phosphohydrolase C-terminal Hydrolase_3 PF08282.12 GBG91117.1 - 3.4e-11 43.4 0.0 3.4e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase NAD_binding_10 PF13460.6 GBG91117.1 - 0.085 12.7 0.3 0.36 10.7 0.2 2.1 2 0 0 2 2 2 0 NAD(P)H-binding RNA_pol_A_bac PF01000.26 GBG91118.1 - 5.2e-28 97.7 0.0 9.9e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GBG91118.1 - 1.5e-21 75.6 0.0 2.3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.7 GBG91118.1 - 0.036 14.7 2.4 0.088 13.4 2.4 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain GAT PF03127.14 GBG91119.1 - 2.6e-14 53.3 0.1 5.1e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 GAT domain GAT PF03127.14 GBG91120.1 - 3.1e-14 53.0 0.1 5.1e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 GAT domain RT_RNaseH_2 PF17919.1 GBG91121.1 - 1.6e-16 60.1 0.0 6.3e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91121.1 - 2.4e-14 53.4 0.0 3.7e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91121.1 - 4.1e-07 30.2 0.0 9.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 GBG91121.1 - 1.6 8.1 19.6 2.4 7.5 19.6 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG91121.1 - 9.2 5.7 8.0 13 5.2 8.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RVT_1 PF00078.27 GBG91122.1 - 6.2e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 GBG91122.1 - 0.12 11.8 27.3 0.15 11.4 27.3 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 GBG91122.1 - 0.49 10.5 29.2 0.71 9.9 29.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG91122.1 - 0.58 9.4 27.8 0.88 8.8 27.8 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG91122.1 - 1.1 7.5 22.4 1.7 6.9 22.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG91122.1 - 1.3 7.2 31.3 1.6 6.8 31.3 1.1 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 GBG91122.1 - 2 7.4 15.0 2.4 7.2 15.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cwf_Cwc_15 PF04889.12 GBG91122.1 - 2.2 8.0 21.8 2.9 7.5 21.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 GBG91122.1 - 6.3 5.5 9.2 7.3 5.2 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 GBG91122.1 - 6.3 3.8 7.1 7.1 3.6 7.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPR3 PF03666.13 GBG91122.1 - 8.8 5.0 8.6 11 4.7 8.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GBG91122.1 - 8.9 4.9 13.9 11 4.7 13.9 1.1 1 0 0 1 1 1 0 Presenilin LysM PF01476.20 GBG91123.1 - 5.9e-14 51.9 0.0 2.6e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 LysM domain DUF3042 PF11240.8 GBG91124.1 - 0.034 14.2 0.3 0.074 13.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Iso_dh PF00180.20 GBG91125.1 - 8.2e-77 258.7 0.0 2.1e-51 175.1 0.0 2.3 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase rve PF00665.26 GBG91125.1 - 0.029 14.6 0.2 0.068 13.4 0.2 1.5 1 0 0 1 1 1 0 Integrase core domain CARD_2 PF16739.5 GBG91125.1 - 0.063 13.3 0.2 18 5.4 0.0 3.0 3 0 0 3 3 3 0 Caspase recruitment domain Lar_restr_allev PF14354.6 GBG91125.1 - 0.087 13.2 0.2 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar CENP-K PF11802.8 GBG91125.1 - 0.25 10.9 2.8 0.37 10.3 2.8 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF4407 PF14362.6 GBG91125.1 - 2.1 7.6 12.1 3.2 7.0 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 GBG91125.1 - 5.3 6.9 14.0 8.5 6.3 14.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 GBG91126.1 - 1.5e-66 224.5 0.0 2e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91126.1 - 2e-32 112.5 0.0 3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG91126.1 - 0.00012 21.5 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GBG91126.1 - 0.00056 19.3 0.0 0.00092 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GBG91126.1 - 0.036 13.7 0.1 0.056 13.0 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Integrase_H2C2 PF17921.1 GBG91127.1 - 8.3e-16 57.9 0.1 2.1e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG91127.1 - 1.6e-09 37.6 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG91127.1 - 1.3e-05 25.4 0.0 2.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91127.1 - 3.6e-05 23.9 0.0 9.9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG91127.1 - 0.0053 17.4 0.0 0.015 15.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91127.1 - 0.0063 17.0 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Clp_N PF02861.20 GBG91128.1 - 3.2e-18 65.6 0.5 3e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component PNP_UDP_1 PF01048.20 GBG91128.1 - 0.029 13.6 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphorylase superfamily DUF2470 PF10615.9 GBG91129.1 - 0.00011 22.8 0.0 0.00022 21.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) RT_RNaseH_2 PF17919.1 GBG91130.1 - 2.7e-21 75.5 0.0 6.8e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91130.1 - 2.8e-21 75.8 0.0 6.2e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91130.1 - 4.3e-11 42.8 0.1 4.3e-11 42.8 0.1 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG91130.1 - 0.055 13.8 0.7 0.25 11.6 0.2 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein Suf PF05843.14 GBG91130.1 - 0.059 13.4 2.2 0.1 12.6 2.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ta0938 PF11494.8 GBG91130.1 - 0.59 10.4 4.7 3.4 8.0 0.1 3.3 3 0 0 3 3 3 0 Ta0938 Presenilin PF01080.17 GBG91130.1 - 1.6 7.4 5.7 2.4 6.9 5.7 1.1 1 0 0 1 1 1 0 Presenilin ADP_ribosyl_GH PF03747.14 GBG91131.1 - 0.016 15.0 0.1 0.035 13.9 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase Retrotrans_gag PF03732.17 GBG91131.1 - 0.053 13.8 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein SNARE PF05739.19 GBG91132.1 - 6.3e-09 35.7 0.1 1.5e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Gp-FAR-1 PF05823.12 GBG91132.1 - 0.0011 19.3 2.1 0.0041 17.5 0.1 2.2 2 0 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ran-binding PF05508.11 GBG91132.1 - 0.0054 15.8 1.3 0.0054 15.8 1.3 1.9 2 0 0 2 2 2 1 RanGTP-binding protein DUF5089 PF17002.5 GBG91132.1 - 0.0093 15.9 7.3 0.0093 15.9 7.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5089) DUF2046 PF09755.9 GBG91132.1 - 0.011 15.0 7.5 0.029 13.6 3.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Spc7 PF08317.11 GBG91132.1 - 0.013 14.4 12.1 0.13 11.1 5.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FliJ PF02050.16 GBG91132.1 - 0.019 15.2 11.2 0.16 12.2 5.2 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Laminin_II PF06009.12 GBG91132.1 - 0.025 14.6 3.4 0.24 11.4 0.9 2.4 2 0 0 2 2 2 0 Laminin Domain II APG17 PF04108.12 GBG91132.1 - 0.034 13.3 6.9 0.054 12.6 3.9 2.0 2 0 0 2 2 2 0 Autophagy protein Apg17 TMPIT PF07851.13 GBG91132.1 - 0.051 12.8 5.7 0.12 11.6 1.5 2.0 2 0 0 2 2 2 0 TMPIT-like protein HAUS-augmin3 PF14932.6 GBG91132.1 - 0.059 12.9 7.7 0.031 13.9 2.8 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 HisKA_3 PF07730.13 GBG91132.1 - 0.12 12.9 2.9 0.6 10.7 0.2 2.6 3 0 0 3 3 2 0 Histidine kinase ERM PF00769.19 GBG91132.1 - 0.16 11.8 10.8 0.055 13.3 4.6 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family T3SSipB PF16535.5 GBG91132.1 - 0.16 12.5 5.6 0.22 12.0 2.2 2.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB ApoO PF09769.9 GBG91132.1 - 0.17 11.9 0.6 0.85 9.6 0.2 2.3 2 1 0 2 2 2 0 Apolipoprotein O DUF2203 PF09969.9 GBG91132.1 - 0.53 11.0 8.3 2.2 9.0 0.3 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Latarcin PF10279.9 GBG91132.1 - 0.57 10.6 7.4 0.56 10.7 1.0 2.5 2 1 0 2 2 2 0 Latarcin precursor Fzo_mitofusin PF04799.13 GBG91132.1 - 0.69 9.5 5.9 2 8.0 1.7 2.8 2 1 1 3 3 3 0 fzo-like conserved region UPF0242 PF06785.11 GBG91132.1 - 0.69 10.0 11.4 0.23 11.6 6.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 GBG91132.1 - 0.74 10.5 13.7 4.6 7.9 6.9 2.6 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF16 PF01519.16 GBG91132.1 - 0.84 10.1 9.6 0.69 10.4 4.5 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 GrpE PF01025.19 GBG91132.1 - 0.85 9.3 12.2 0.13 11.9 1.7 2.9 2 1 1 3 3 3 0 GrpE Tropomyosin_1 PF12718.7 GBG91132.1 - 1.1 9.5 15.2 0.53 10.4 8.2 2.3 2 0 0 2 2 2 0 Tropomyosin like XhlA PF10779.9 GBG91132.1 - 1.2 9.4 8.3 0.2 11.9 0.4 2.9 3 1 0 3 3 2 0 Haemolysin XhlA DUF745 PF05335.13 GBG91132.1 - 1.6 8.4 10.0 0.093 12.5 3.4 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF4140 PF13600.6 GBG91132.1 - 2.3 8.7 9.5 2.6 8.5 0.3 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 GBG91132.1 - 3.9 7.9 9.1 0.91 9.9 2.1 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF641 PF04859.12 GBG91132.1 - 4.6 7.6 9.6 4.2 7.7 3.9 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 GBG91132.1 - 6.1 7.3 9.5 9.1 6.8 1.3 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) CdvA PF18822.1 GBG91132.1 - 7.8 6.4 11.9 1.5 8.7 1.9 3.3 2 2 1 3 3 3 0 CdvA-like coiled-coil domain YabA PF06156.13 GBG91132.1 - 10 6.9 8.2 11 6.8 2.7 2.5 2 1 0 2 2 2 0 Initiation control protein YabA Gpr1_Fun34_YaaH PF01184.19 GBG91134.1 - 7.5e-39 133.5 20.1 1.3e-38 132.7 20.1 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family RVT_1 PF00078.27 GBG91134.1 - 1.6e-22 80.1 0.0 2.5e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91134.1 - 1.4e-10 41.4 0.0 2.4e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91134.1 - 4.3e-07 29.9 0.0 0.039 14.0 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Tetraspanin PF00335.20 GBG91134.1 - 0.43 10.3 5.4 0.75 9.5 5.4 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF202 PF02656.15 GBG91134.1 - 1.7 9.2 11.5 4.6 7.8 0.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF202) Gpr1_Fun34_YaaH PF01184.19 GBG91135.1 - 4e-38 131.1 22.5 5.1e-38 130.8 22.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 GBG91135.1 - 0.055 13.9 14.5 0.53 10.8 0.7 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 GBG91135.1 - 1.8 8.2 9.9 1.8 8.2 8.9 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF883 PF05957.13 GBG91136.1 - 0.044 14.4 1.0 3.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Gpr1_Fun34_YaaH PF01184.19 GBG91137.1 - 3.8e-40 137.7 21.3 4.9e-40 137.4 21.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 GBG91137.1 - 0.047 14.1 15.3 0.51 10.8 0.8 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 GBG91137.1 - 1.3 8.7 8.5 1.3 8.7 7.3 1.6 1 1 0 1 1 1 0 Tetraspanin family Gpr1_Fun34_YaaH PF01184.19 GBG91138.1 - 1.1e-40 139.4 21.5 1.5e-40 139.1 21.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 GBG91138.1 - 0.21 12.1 15.1 1.2 9.6 1.1 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 GBG91138.1 - 5.8 6.6 9.6 6.6 6.4 8.6 1.6 1 1 0 1 1 1 0 Tetraspanin family zf-CCHC PF00098.23 GBG91139.1 - 6.1e-05 22.9 4.4 0.0001 22.2 4.4 1.4 1 0 0 1 1 1 1 Zinc knuckle GBP_repeat PF02526.14 GBG91139.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycophorin-binding protein zf-CCHC_2 PF13696.6 GBG91139.1 - 0.32 10.9 6.5 0.49 10.3 6.5 1.3 1 0 0 1 1 1 0 Zinc knuckle PAF-AH_p_II PF03403.13 GBG91139.1 - 3.2 6.2 5.2 4.6 5.7 5.2 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II RGS_DHEX PF18148.1 GBG91139.1 - 4.7 7.4 10.1 0.48 10.6 3.7 2.3 1 1 1 2 2 2 0 Regulator of G-protein signalling DHEX domain ALMT PF11744.8 GBG91139.1 - 4.8 5.9 5.8 8.6 5.1 5.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2681 PF10883.8 GBG91139.1 - 9.4 6.7 12.0 34 4.9 12.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Gpr1_Fun34_YaaH PF01184.19 GBG91140.1 - 1.6e-41 142.2 17.8 2.1e-41 141.8 17.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 GBG91140.1 - 0.11 13.0 13.7 0.59 10.6 0.4 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 GBG91140.1 - 0.15 11.7 4.9 0.28 10.8 4.9 1.5 1 0 0 1 1 1 0 Tetraspanin family RT_RNaseH_2 PF17919.1 GBG91141.1 - 1.5e-27 95.6 0.0 3e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91141.1 - 8.2e-25 87.1 0.0 1.9e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG91141.1 - 0.00015 22.2 0.1 0.00041 20.8 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG91141.1 - 0.00016 21.5 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91141.1 - 0.00046 20.8 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG91141.1 - 0.0023 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF4746 PF15928.5 GBG91141.1 - 1.8 7.9 16.1 9.3 5.6 14.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) FRQ PF09421.10 GBG91141.1 - 2.1 6.3 6.3 2.9 5.8 6.3 1.1 1 0 0 1 1 1 0 Frequency clock protein Gpr1_Fun34_YaaH PF01184.19 GBG91142.1 - 1.6e-39 135.6 23.0 2e-39 135.3 23.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 GBG91142.1 - 0.036 14.5 14.4 0.45 11.0 0.4 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 GBG91142.1 - 0.59 9.8 9.5 0.62 9.7 8.5 1.6 1 1 0 1 1 1 0 Tetraspanin family Gpr1_Fun34_YaaH PF01184.19 GBG91143.1 - 1e-38 133.1 23.1 1.3e-38 132.7 23.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 GBG91143.1 - 0.044 14.2 14.5 0.48 10.9 0.4 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 GBG91143.1 - 0.34 10.6 9.2 0.35 10.5 8.1 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF659 PF04937.15 GBG91144.1 - 3e-18 66.1 0.0 4.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91144.1 - 0.00024 20.8 0.1 0.00046 19.9 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG91145.1 - 8.7e-41 139.9 0.1 1.3e-40 139.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91146.1 - 4.4e-30 103.7 0.0 3.6e-15 55.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91146.1 - 8.2e-30 103.2 0.0 1.8e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91146.1 - 5.2e-28 98.1 0.1 9.5e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG91146.1 - 1.5e-11 44.0 1.6 1.6e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain IQ PF00612.27 GBG91147.1 - 2.5e-12 45.4 12.2 4.8e-05 22.8 0.4 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Mucin PF01456.17 GBG91147.1 - 0.09 12.8 22.0 0.14 12.2 22.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Tim17 PF02466.19 GBG91148.1 - 4.1e-06 27.2 7.0 2.4e-05 24.7 7.0 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.6 GBG91148.1 - 0.022 14.5 4.8 0.022 14.5 4.8 3.2 3 0 0 3 3 3 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 GBG91148.1 - 0.03 14.0 11.9 0.033 13.9 1.8 2.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 GBG91148.1 - 0.59 10.2 14.1 0.56 10.2 2.9 2.7 2 0 0 2 2 2 0 Glycine zipper zf-CCCH PF00642.24 GBG91149.1 - 1.7e-22 78.7 43.8 2.2e-08 33.8 6.7 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GBG91149.1 - 1.8e-14 53.2 39.4 0.00026 20.9 4.6 4.4 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 GBG91149.1 - 2.3e-14 52.8 46.8 0.0007 19.3 6.4 4.3 4 0 0 4 4 4 4 CCCH-type zinc finger KH_1 PF00013.29 GBG91149.1 - 5.1e-14 51.9 1.1 9.5e-14 51.0 1.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCCH_2 PF14608.6 GBG91149.1 - 1.9e-09 37.7 37.7 0.014 15.9 1.1 4.5 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger oligo_HPY PF08352.12 GBG91149.1 - 1.9e-06 28.3 15.3 0.059 13.9 0.6 4.3 4 0 0 4 4 4 3 Oligopeptide/dipeptide transporter, C-terminal region Torus PF16131.5 GBG91149.1 - 1.8e-05 25.4 18.8 0.022 15.4 1.4 4.2 2 1 1 4 4 4 2 Torus domain KH_2 PF07650.17 GBG91149.1 - 0.0041 16.9 0.3 0.0081 16.0 0.3 1.5 1 0 0 1 1 1 1 KH domain KH_5 PF13184.6 GBG91149.1 - 0.026 14.6 0.0 0.1 12.7 0.2 1.9 2 0 0 2 2 2 0 NusA-like KH domain ATX_III PF08098.11 GBG91149.1 - 0.14 12.2 0.3 0.14 12.2 0.3 4.3 4 0 0 4 4 4 0 Anemonia sulcata toxin III family zf-CCCH_3 PF15663.5 GBG91149.1 - 2.7 8.3 19.3 8.5 6.6 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger containing family Phage_holin_3_6 PF07332.11 GBG91150.1 - 1.1 9.3 19.0 2.4 8.2 19.0 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2892 PF11127.8 GBG91150.1 - 8.8 6.4 9.6 18 5.5 9.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Retrotrans_gag PF03732.17 GBG91151.1 - 0.077 13.3 0.2 0.22 11.8 0.1 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG91152.1 - 1.7e-06 27.7 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG91153.1 - 0.00046 20.1 3.9 0.0012 18.9 3.9 1.7 1 0 0 1 1 1 1 Zinc knuckle AAA_23 PF13476.6 GBG91153.1 - 0.047 14.2 9.9 0.11 13.0 9.9 1.6 1 0 0 1 1 1 0 AAA domain zf-CCHC_3 PF13917.6 GBG91153.1 - 0.048 13.6 1.7 0.17 11.9 1.7 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG91153.1 - 0.12 12.3 1.7 0.27 11.1 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle AAA_15 PF13175.6 GBG91153.1 - 0.18 11.5 3.9 0.27 10.9 3.9 1.2 1 0 0 1 1 1 0 AAA ATPase domain zf-CCHC_5 PF14787.6 GBG91153.1 - 0.33 10.7 2.9 0.7 9.7 2.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger ALMT PF11744.8 GBG91153.1 - 0.35 9.6 8.6 0.69 8.7 8.6 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 GBG91153.1 - 1.8 6.4 6.8 2.5 5.9 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PV-1 PF06637.11 GBG91153.1 - 2.9 6.6 17.2 4.6 6.0 17.2 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Tho2 PF11262.8 GBG91153.1 - 5.8 6.0 10.8 9.5 5.3 10.8 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Presenilin PF01080.17 GBG91153.1 - 6.4 5.4 9.2 8.7 5.0 9.2 1.3 1 0 0 1 1 1 0 Presenilin DUF659 PF04937.15 GBG91154.1 - 6e-12 45.7 0.0 1.2e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cwf_Cwc_15 PF04889.12 GBG91154.1 - 0.01 15.6 11.5 0.017 14.9 11.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GBG91154.1 - 0.071 12.5 11.5 0.11 11.9 11.5 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GBG91154.1 - 1.3 7.0 17.1 1.8 6.5 17.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG91154.1 - 2.1 6.5 11.1 2.9 6.0 11.1 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 GBG91154.1 - 5 7.0 15.7 10 6.0 15.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit alpha-hel2 PF14456.6 GBG91155.1 - 0.014 14.8 0.3 0.029 13.7 0.3 1.5 1 0 0 1 1 1 0 Alpha-helical domain 2 Retrotrans_gag PF03732.17 GBG91155.1 - 0.018 15.3 0.1 0.093 13.0 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein DUF659 PF04937.15 GBG91156.1 - 2.7e-22 79.2 0.0 4.2e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91156.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region rve PF00665.26 GBG91157.1 - 9.9e-10 38.6 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG91157.1 - 0.0063 16.3 0.2 0.03 14.1 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain gag-asp_proteas PF13975.6 GBG91157.1 - 0.037 14.6 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG91157.1 - 0.12 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Sel1 PF08238.12 GBG91158.1 - 3.7e-23 81.4 21.6 1.6e-06 28.6 0.3 7.8 7 1 0 7 7 7 5 Sel1 repeat FlgN PF05130.12 GBG91158.1 - 0.0052 17.3 3.8 0.0052 17.3 3.8 2.5 3 0 0 3 3 3 1 FlgN protein DUF3450 PF11932.8 GBG91158.1 - 0.076 12.3 2.6 0.18 11.1 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF812 PF05667.11 GBG91158.1 - 0.14 11.0 6.7 0.27 10.1 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PhoU_div PF01865.16 GBG91158.1 - 0.4 10.0 4.6 0.13 11.5 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function DUF47 Mod_r PF07200.13 GBG91158.1 - 0.4 10.8 13.7 0.099 12.7 3.2 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein EAP30 PF04157.16 GBG91158.1 - 0.71 9.1 5.3 0.14 11.4 0.2 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family ATG16 PF08614.11 GBG91158.1 - 0.75 10.0 16.9 0.022 15.0 5.2 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 GBG91158.1 - 1.6 8.8 6.8 4.2 7.4 6.8 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 GBG91159.1 - 0.0077 16.4 1.0 0.026 14.7 1.0 1.9 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF2385 PF09539.10 GBG91159.1 - 0.014 15.9 0.2 0.4 11.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) CCDC85 PF10226.9 GBG91159.1 - 0.014 15.0 0.2 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 CCDC85 family bZIP_1 PF00170.21 GBG91159.1 - 0.021 14.9 0.8 0.084 13.0 0.8 2.1 1 0 0 1 1 1 0 bZIP transcription factor Hepcidin PF06446.12 GBG91159.1 - 0.19 12.2 0.2 0.54 10.7 0.2 1.8 1 0 0 1 1 1 0 Hepcidin DivIC PF04977.15 GBG91159.1 - 0.45 10.3 3.5 0.76 9.6 2.4 1.9 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 GBG91159.1 - 2.2 8.4 9.5 0.13 12.4 3.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 GBG91159.1 - 2.3 8.6 8.4 0.38 11.1 1.0 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain ZapB PF06005.12 GBG91159.1 - 3.1 8.3 8.8 0.86 10.1 2.8 2.7 2 0 0 2 2 2 0 Cell division protein ZapB RT_RNaseH PF17917.1 GBG91160.1 - 2.7e-16 59.7 0.2 6.5e-16 58.5 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91160.1 - 1.9e-14 53.5 0.2 7.3e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG91160.1 - 8.9e-13 48.5 0.0 2.2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG91160.1 - 1.3e-09 38.0 0.0 3.5e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91160.1 - 1.9e-07 30.8 0.0 4.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG91160.1 - 0.0042 17.3 0.0 0.0096 16.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger CENP-Q PF13094.6 GBG91160.1 - 0.071 13.3 4.2 0.057 13.6 1.5 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RVT_1 PF00078.27 GBG91161.1 - 7.2e-18 64.9 0.1 1.1e-17 64.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ER-remodelling PF14755.6 GBG91162.1 - 0.023 15.0 2.8 0.05 13.9 2.8 1.5 1 0 0 1 1 1 0 Intracellular membrane remodeller Mito_carr PF00153.27 GBG91163.1 - 1.4e-45 153.1 4.1 9.3e-17 60.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HTH_21 PF13276.6 GBG91163.1 - 0.0018 18.4 0.1 1.3 9.2 0.0 3.2 3 0 0 3 3 3 2 HTH-like domain DNA_pol_phi PF04931.13 GBG91164.1 - 9e-130 434.1 2.6 9e-130 434.1 2.6 2.2 2 1 1 3 3 3 1 DNA polymerase phi Ribosomal_S2 PF00318.20 GBG91165.1 - 2.9e-25 88.8 0.0 1.1e-11 44.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Phage_sheath_1 PF04984.14 GBG91165.1 - 0.27 11.1 4.2 0.54 10.1 4.2 1.4 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain DUF659 PF04937.15 GBG91166.1 - 2.6e-28 98.8 0.2 3.8e-28 98.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG91166.1 - 7.3e-08 32.2 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91166.1 - 4.9e-05 23.3 0.1 0.00011 22.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG91167.1 - 2e-19 69.8 0.0 4.2e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91167.1 - 3.3e-18 65.6 0.0 8e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GRP PF07172.11 GBG91167.1 - 0.43 11.3 5.6 1.3 9.8 5.6 1.8 1 0 0 1 1 1 0 Glycine rich protein family Asp_protease_2 PF13650.6 GBG91168.1 - 0.015 15.9 0.5 0.091 13.4 0.1 2.5 3 0 0 3 3 3 0 Aspartyl protease cNMP_binding PF00027.29 GBG91168.1 - 0.087 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Topo_Zn_Ribbon PF08272.11 GBG91168.1 - 0.099 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Rubredoxin_2 PF18073.1 GBG91170.1 - 0.00019 21.1 1.5 0.00075 19.2 1.5 1.9 1 1 0 1 1 1 1 Rubredoxin metal binding domain XAF1_C PF18608.1 GBG91170.1 - 0.0018 17.8 4.1 0.0058 16.2 4.1 1.7 1 1 0 1 1 1 1 XIAP-associated factor 1 C-terminal domain zf-RanBP PF00641.18 GBG91170.1 - 0.004 16.5 1.6 0.004 16.5 1.6 2.1 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Zn_Tnp_IS1595 PF12760.7 GBG91170.1 - 0.011 15.7 1.3 0.015 15.2 1.3 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 GBG91170.1 - 0.063 13.3 1.6 0.1 12.7 1.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn_ribbon_SprT PF17283.2 GBG91170.1 - 0.1 12.5 1.4 0.17 11.8 1.4 1.3 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DAGK_acc PF00609.19 GBG91171.1 - 2.8e-37 128.5 0.0 4.7e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 GBG91171.1 - 4.4e-23 81.3 0.0 9.5e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RT_RNaseH PF17917.1 GBG91172.1 - 1.2e-30 105.9 0.1 3.8e-30 104.3 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91172.1 - 1.6e-30 105.1 0.0 5.1e-30 103.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase_Tyr PF07714.17 GBG91172.1 - 3.2e-22 79.1 0.0 6.5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG91172.1 - 1.7e-21 76.8 0.0 3.6e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CENP-F_leu_zip PF10473.9 GBG91172.1 - 0.00014 21.9 32.9 0.08 13.0 9.9 3.8 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.6 GBG91172.1 - 0.0078 16.5 25.4 0.56 10.5 3.1 4.2 3 1 2 5 5 4 3 Domain of unknown function (DUF4164) Spc24 PF08286.11 GBG91172.1 - 0.016 15.4 17.8 0.15 12.3 2.2 3.6 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 GBG91172.1 - 0.16 12.3 20.7 3.9 7.9 2.4 5.4 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.6 GBG91172.1 - 0.23 11.9 24.8 1.6 9.1 4.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) L1R_F9L PF02442.17 GBG91172.1 - 0.25 11.2 2.5 1.1 9.1 1.8 2.1 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Phage_GPO PF05929.11 GBG91172.1 - 0.41 10.2 0.0 0.41 10.2 0.0 3.6 2 1 2 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase BLOC1_2 PF10046.9 GBG91172.1 - 0.43 10.9 12.9 2.6 8.4 2.7 3.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CM_2 PF01817.21 GBG91172.1 - 0.57 10.6 5.3 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Chorismate mutase type II Sipho_Gp157 PF05565.11 GBG91172.1 - 0.81 9.7 14.7 1.3 9.1 1.1 2.6 2 1 0 2 2 2 0 Siphovirus Gp157 Med9 PF07544.13 GBG91172.1 - 1 9.5 15.3 4 7.6 3.3 3.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.21 GBG91172.1 - 1.1 9.4 23.7 5.4 7.2 1.2 4.4 3 2 1 4 4 4 0 bZIP transcription factor DUF2968 PF11180.8 GBG91172.1 - 1.9 8.1 19.2 3.4 7.3 8.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) Filament PF00038.21 GBG91172.1 - 3.2 7.2 26.2 0.34 10.4 4.4 3.1 1 1 2 3 3 3 0 Intermediate filament protein AAA_lid_9 PF17871.1 GBG91172.1 - 7.5 6.5 0.0 7.5 6.5 0.0 4.1 4 0 0 4 4 4 0 AAA lid domain Pkinase PF00069.25 GBG91173.1 - 2.1e-24 86.3 0.0 7.2e-24 84.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91173.1 - 2.3e-22 79.5 0.0 5.2e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG91173.1 - 7.8e-07 29.7 1.2 1.2 10.1 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG91173.1 - 0.00065 19.9 0.1 0.35 11.2 0.0 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zf-CCHC PF00098.23 GBG91173.1 - 0.001 19.1 2.1 0.0031 17.5 2.1 1.9 1 0 0 1 1 1 1 Zinc knuckle eIF2A PF08662.11 GBG91173.1 - 0.041 13.8 0.1 0.16 11.9 0.1 1.9 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DUF262 PF03235.14 GBG91174.1 - 0.84 9.8 7.6 3.5 7.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF262 DUF2721 PF11026.8 GBG91175.1 - 0.081 12.8 16.0 1.5 8.7 0.2 5.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2721) DUF948 PF06103.11 GBG91175.1 - 0.2 11.9 11.4 3.2 8.1 0.1 4.4 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 GBG91175.1 - 0.42 10.6 10.4 9.9 6.2 0.1 4.1 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.16 GBG91175.1 - 4.9 6.9 16.8 6.4 6.5 0.4 4.4 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 DUF713 PF05218.14 GBG91175.1 - 5.7 6.6 35.0 0.14 11.9 2.3 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF713) LptF_LptG PF03739.14 GBG91175.1 - 9 5.0 13.2 67 2.2 13.2 2.3 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Presenilin PF01080.17 GBG91176.1 - 0.0025 16.7 8.8 0.0028 16.5 8.8 1.1 1 0 0 1 1 1 1 Presenilin SLC12 PF03522.15 GBG91176.1 - 0.046 12.7 2.1 0.061 12.3 2.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PBP1_TM PF14812.6 GBG91176.1 - 0.048 14.0 1.0 0.048 14.0 1.0 2.9 2 1 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Apt1 PF10351.9 GBG91176.1 - 0.082 11.7 1.9 0.097 11.5 1.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 GBG91176.1 - 0.14 11.0 10.1 0.17 10.7 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Caldesmon PF02029.15 GBG91176.1 - 0.35 9.6 33.1 0.52 9.0 33.1 1.2 1 0 0 1 1 1 0 Caldesmon BUD22 PF09073.10 GBG91176.1 - 0.73 9.1 35.5 0.89 8.8 35.5 1.1 1 0 0 1 1 1 0 BUD22 SpoIIIAH PF12685.7 GBG91176.1 - 0.94 9.3 17.4 0.1 12.4 0.5 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein CDC45 PF02724.14 GBG91176.1 - 2.3 6.4 33.8 0.057 11.7 3.7 2.0 2 0 0 2 2 2 0 CDC45-like protein RPA43_OB PF17875.1 GBG91176.1 - 2.8 8.6 21.7 0.19 12.4 2.4 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF3408 PF11888.8 GBG91176.1 - 7.8 6.6 31.0 0.99 9.5 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Pkinase_Tyr PF07714.17 GBG91177.1 - 1.5e-22 80.2 0.0 2.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG91177.1 - 1.6e-22 80.2 0.0 3.1e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Atg14 PF10186.9 GBG91177.1 - 0.0048 16.0 12.6 0.0092 15.1 12.6 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 GBG91177.1 - 0.15 12.2 5.2 0.4 10.9 5.2 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CEND1 PF15677.5 GBG91177.1 - 3.9 8.0 7.8 7.5 7.1 7.8 1.4 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 TMF_DNA_bd PF12329.8 GBG91177.1 - 4.3 7.4 14.0 4.5 7.4 9.3 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.11 GBG91177.1 - 5.8 7.2 8.4 72 3.7 8.4 2.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF659 PF04937.15 GBG91178.1 - 1.3e-34 119.2 0.4 2.1e-34 118.6 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91178.1 - 0.00022 20.9 0.1 0.00045 20.0 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RdRP PF05183.12 GBG91179.1 - 4.1e-89 299.8 0.0 5.7e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RT_RNaseH_2 PF17919.1 GBG91180.1 - 3.2e-24 84.9 0.0 6.2e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91180.1 - 7.6e-22 77.6 0.0 2.1e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91180.1 - 2.4e-09 37.0 0.0 4.3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG91180.1 - 0.00021 21.8 0.1 0.00049 20.6 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91180.1 - 0.0051 17.4 0.1 0.011 16.3 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG91180.1 - 0.0079 16.0 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG91181.1 - 0.0044 17.3 2.4 0.026 14.8 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein Exo_endo_phos PF03372.23 GBG91182.1 - 1.5e-19 70.5 0.0 1.3e-13 51.1 0.0 3.1 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family zf_CCCH_4 PF18345.1 GBG91182.1 - 0.011 15.7 1.0 0.093 12.8 0.1 2.7 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 GBG91182.1 - 0.022 14.7 0.2 0.022 14.7 0.2 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Chromo PF00385.24 GBG91183.1 - 0.00032 20.5 0.6 0.00066 19.5 0.1 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Vac7 PF12751.7 GBG91183.1 - 0.034 13.6 3.1 0.061 12.8 3.1 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF2052 PF09747.9 GBG91183.1 - 1.8 8.6 18.2 11 6.1 18.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CDC27 PF09507.10 GBG91183.1 - 2.3 7.5 17.8 3.8 6.8 17.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDRGK PF09756.9 GBG91183.1 - 5.5 6.5 24.9 11 5.5 24.9 1.4 1 0 0 1 1 1 0 DDRGK domain zf-MYND PF01753.18 GBG91184.1 - 5.5e-08 32.8 16.1 5.5e-08 32.8 16.1 2.9 2 1 0 2 2 2 1 MYND finger DUF2457 PF10446.9 GBG91184.1 - 0.02 14.0 12.8 0.038 13.2 12.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 GBG91184.1 - 0.058 13.1 12.9 0.018 14.8 7.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C6H2 PF15801.5 GBG91184.1 - 2.4 8.5 26.0 63 4.0 18.8 3.4 2 2 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Arm PF00514.23 GBG91185.1 - 0.0033 17.4 0.7 0.012 15.6 0.1 2.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat BUD22 PF09073.10 GBG91185.1 - 0.027 13.8 35.9 0.0078 15.6 27.3 2.6 2 0 0 2 2 2 0 BUD22 BSP_II PF05432.11 GBG91185.1 - 4.3 7.0 39.4 3.8 7.1 27.8 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) XRN_M PF17846.1 GBG91185.1 - 5.1 5.9 8.9 8.4 5.2 8.9 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Serglycin PF04360.12 GBG91185.1 - 8.8 6.3 17.8 0.021 14.8 2.8 3.3 3 0 0 3 3 3 0 Serglycin ARS2 PF04959.13 GBG91187.1 - 0.0046 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Integrase_H2C2 PF17921.1 GBG91188.1 - 1.8e-31 108.0 0.1 6.2e-14 51.8 0.1 3.8 3 0 0 3 3 3 2 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG91188.1 - 4.4e-30 104.1 3.9 3.5e-16 59.4 0.1 3.6 2 1 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91188.1 - 1e-21 76.8 0.2 3.7e-12 46.2 0.0 3.1 2 1 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91188.1 - 2.4e-16 60.0 0.0 4.8e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG91188.1 - 4.5e-15 55.9 0.0 2.2e-11 44.0 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG91188.1 - 1.4e-07 31.6 0.0 0.035 14.3 0.0 3.0 2 0 0 2 2 2 2 H2C2 zinc finger STI1 PF17830.1 GBG91188.1 - 0.0029 17.5 1.0 0.48 10.4 0.1 2.9 2 0 0 2 2 2 1 STI1 domain DUF659 PF04937.15 GBG91189.1 - 1.2e-26 93.4 0.0 2.5e-25 89.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Nop16 PF09420.10 GBG91190.1 - 0.33 11.0 12.5 0.4 10.7 12.4 1.3 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 PAP1 PF08601.10 GBG91190.1 - 0.71 9.5 14.1 0.82 9.3 14.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 RVT_1 PF00078.27 GBG91191.1 - 4.9e-20 72.0 0.3 2.6e-10 40.2 0.2 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91191.1 - 1.7e-17 63.2 0.1 4.2e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG91191.1 - 1.2e-12 48.0 0.1 2.6e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG91191.1 - 3.2e-12 46.7 0.0 9e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG91191.1 - 2e-06 27.8 0.2 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG91191.1 - 9.8e-05 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG91191.1 - 0.0029 17.8 0.0 0.0077 16.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG91191.1 - 0.0079 16.0 0.0 0.028 14.2 0.0 1.9 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 GBG91191.1 - 0.017 15.7 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG91191.1 - 0.037 14.6 0.0 0.088 13.4 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG91192.1 - 1.6e-15 57.3 0.3 5e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91192.1 - 1.1e-06 29.1 0.0 3.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91192.1 - 1.5e-05 25.5 0.0 5.9e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG91192.1 - 2.9e-05 23.8 0.0 6.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG91192.1 - 0.00028 21.1 4.1 0.00092 19.4 0.0 3.5 4 1 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG91192.1 - 0.00043 20.1 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease NPV_P10 PF05531.12 GBG91192.1 - 0.12 12.8 1.2 3.5 8.1 0.2 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RT_RNaseH PF17917.1 GBG91193.1 - 2.7e-30 104.7 0.1 1e-29 102.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91193.1 - 3.3e-30 104.1 0.0 8.4e-30 102.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91193.1 - 0.042 13.4 0.1 0.084 12.4 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG91193.1 - 0.07 12.7 0.0 0.07 12.7 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Integrase_H2C2 PF17921.1 GBG91194.1 - 1.7e-21 76.0 0.1 3.2e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91194.1 - 1.3e-15 57.6 0.0 2.9e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91194.1 - 0.0016 18.6 0.0 0.0037 17.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG91194.1 - 0.069 12.9 0.1 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain VAPB_antitox PF02697.14 GBG91194.1 - 0.083 13.7 0.8 0.24 12.2 0.8 1.7 1 0 0 1 1 1 0 Putative antitoxin RT_RNaseH_2 PF17919.1 GBG91195.1 - 1.5e-12 47.4 0.0 3.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG91195.1 - 1.9e-10 41.0 0.0 5.8e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG91195.1 - 5.6e-10 39.4 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG91195.1 - 4.3e-05 24.0 0.0 0.00015 22.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91195.1 - 0.0046 17.6 0.0 0.015 15.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG91195.1 - 0.0053 16.5 1.1 0.01 15.6 1.1 1.4 1 0 0 1 1 1 1 Aspartyl protease THOC7 PF05615.13 GBG91195.1 - 0.045 14.0 2.8 0.13 12.5 2.8 1.8 1 0 0 1 1 1 0 Tho complex subunit 7 RVP PF00077.20 GBG91195.1 - 0.069 13.5 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG91196.1 - 0.0003 20.5 0.0 0.00095 18.9 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region SAPS PF04499.15 GBG91196.1 - 0.43 9.3 1.0 0.65 8.7 1.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 GBG91196.1 - 0.64 9.4 22.2 1.2 8.5 22.2 1.3 1 0 0 1 1 1 0 SDA1 Connexin PF00029.19 GBG91196.1 - 0.76 9.5 4.5 2.4 7.8 4.5 1.7 1 1 0 1 1 1 0 Connexin Presenilin PF01080.17 GBG91196.1 - 3.9 6.1 5.6 5.7 5.6 5.6 1.1 1 0 0 1 1 1 0 Presenilin DUF659 PF04937.15 GBG91197.1 - 9.9e-33 113.2 0.0 1.7e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91197.1 - 1.1e-07 31.5 0.6 3.1e-07 30.1 0.2 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region SDA1 PF05285.12 GBG91199.1 - 2.4e-05 23.9 25.8 2.4e-05 23.9 25.8 1.1 1 0 0 1 1 1 1 SDA1 Caldesmon PF02029.15 GBG91199.1 - 3.2e-05 22.9 18.3 3.2e-05 22.9 18.3 1.2 1 0 0 1 1 1 1 Caldesmon CDC45 PF02724.14 GBG91199.1 - 0.00021 19.8 17.3 0.00021 19.8 17.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Lin-8 PF03353.15 GBG91199.1 - 0.0016 18.1 8.2 0.0016 18.1 8.2 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 GBG91199.1 - 0.0021 17.5 22.9 0.0021 17.5 22.9 1.1 1 0 0 1 1 1 1 BUD22 SpoIIP PF07454.11 GBG91199.1 - 0.0026 17.3 8.0 0.0028 17.2 8.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 GBG91199.1 - 0.01 14.7 9.7 0.0087 14.9 9.7 1.2 1 0 0 1 1 1 0 Presenilin SpoIIIAH PF12685.7 GBG91199.1 - 0.015 15.1 12.3 0.016 15.1 12.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2151 PF10221.9 GBG91199.1 - 0.02 13.5 5.5 0.017 13.8 5.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SLC12 PF03522.15 GBG91199.1 - 0.037 13.1 2.3 0.03 13.3 2.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Nop14 PF04147.12 GBG91199.1 - 0.072 11.3 36.6 0.079 11.2 36.6 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 GBG91199.1 - 0.072 11.2 5.4 0.059 11.5 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDM10 PF12519.8 GBG91199.1 - 0.084 11.7 1.8 0.07 12.0 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Zip PF02535.22 GBG91199.1 - 0.087 12.0 7.0 0.092 12.0 7.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S64 PF08192.11 GBG91199.1 - 0.11 10.9 2.9 0.095 11.2 2.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Plasmodium_Vir PF05795.11 GBG91199.1 - 0.17 11.3 8.7 0.2 11.0 8.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Apt1 PF10351.9 GBG91199.1 - 0.43 9.4 5.9 0.48 9.2 5.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RP-C_C PF11800.8 GBG91199.1 - 0.59 10.2 5.6 0.57 10.3 5.6 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region RNA_pol_Rpc4 PF05132.14 GBG91199.1 - 8.9 6.7 18.5 2.9 8.3 15.7 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF5427 PF10310.9 GBG91199.1 - 9.1 5.1 19.9 13 4.6 19.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Myb_DNA-bind_4 PF13837.6 GBG91200.1 - 7.6e-09 35.8 0.2 1.7e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG91201.1 - 3.5e-33 114.5 0.0 2e-32 112.1 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91201.1 - 1.9e-17 63.6 0.0 3.1e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91201.1 - 1.2e-06 28.3 1.5 0.0052 16.5 0.1 3.2 2 1 0 2 2 2 2 Transposase DDE domain Gln-synt_N PF03951.19 GBG91202.1 - 3.4e-12 45.9 0.0 5.3e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Myb_DNA-bind_4 PF13837.6 GBG91203.1 - 9.8e-05 22.7 0.1 0.00053 20.3 0.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Zein-binding PF04576.15 GBG91204.1 - 2.9e-18 65.9 10.2 2.9e-18 65.9 10.2 2.2 2 0 0 2 2 2 1 Zein-binding SUIM_assoc PF16619.5 GBG91204.1 - 0.00045 20.2 5.5 0.0018 18.3 5.5 2.0 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 TMEM171 PF15471.6 GBG91204.1 - 0.1 11.6 1.0 0.2 10.6 1.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Dimer_Tnp_hAT PF05699.14 GBG91205.1 - 0.003 17.3 0.3 0.0099 15.6 0.3 1.9 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_Tnp_4 PF13359.6 GBG91207.1 - 3.7e-24 85.2 0.0 1.2e-23 83.5 0.0 1.9 2 1 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91207.1 - 3.4e-13 49.6 0.0 6.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91207.1 - 0.012 15.2 0.2 0.44 10.1 0.2 2.3 2 0 0 2 2 2 0 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG91208.1 - 1.8e-31 108.2 0.1 3.3e-31 107.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91208.1 - 5.2e-26 91.5 0.1 7.8e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91208.1 - 7.4e-24 84.1 0.0 1.3e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop53 PF07767.11 GBG91209.1 - 0.0083 15.6 5.2 0.01 15.3 5.2 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4604 PF15377.6 GBG91209.1 - 0.0089 16.5 5.4 0.01 16.3 5.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) F_actin_bund_C PF18060.1 GBG91209.1 - 0.036 14.2 1.6 0.052 13.7 1.6 1.3 1 0 0 1 1 1 0 F actin bundling C terminal Myc_N PF01056.18 GBG91209.1 - 0.055 13.4 1.8 0.057 13.3 1.8 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Gln-synt_C PF00120.24 GBG91209.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain Gln-synt_C PF00120.24 GBG91211.1 - 1.7e-15 56.9 0.0 1.7e-12 47.0 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GBG91211.1 - 5.8e-11 42.0 0.0 1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DDE_Tnp_4 PF13359.6 GBG91212.1 - 2.8e-25 88.8 0.0 1e-24 87.0 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91212.1 - 9.3e-12 45.0 0.1 9e-10 38.5 0.1 2.1 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91212.1 - 0.0013 18.4 0.1 1.2 8.7 0.0 2.3 1 1 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG91212.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG91213.1 - 1.2e-31 109.6 0.0 4.9e-31 107.5 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91213.1 - 1.5e-15 57.3 0.0 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91213.1 - 0.0085 15.8 0.1 0.51 9.9 0.0 2.5 2 1 0 2 2 2 1 Transposase DDE domain DUF983 PF06170.12 GBG91214.1 - 0.94 9.9 13.8 2.5 8.6 13.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF983) HSP70 PF00012.20 GBG91217.1 - 1.1e-170 568.8 0.0 1.3e-170 568.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG91217.1 - 9.1e-14 51.0 0.0 1.7e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 GBG91217.1 - 0.00034 21.0 0.5 0.25 11.8 0.0 3.1 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 GBG91217.1 - 0.011 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 GBG91217.1 - 0.044 13.1 0.1 0.39 9.9 0.0 2.5 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase HSP70 PF00012.20 GBG91218.1 - 5.2e-165 550.0 0.0 6.3e-165 549.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG91218.1 - 1.4e-16 60.2 0.3 9.2e-13 47.7 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 GBG91218.1 - 0.0012 19.2 0.2 0.18 12.2 0.0 3.1 2 2 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.16 GBG91218.1 - 0.0031 17.3 0.1 0.0066 16.2 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Ppx-GppA PF02541.16 GBG91218.1 - 0.057 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Hydantoinase_A PF01968.18 GBG91218.1 - 0.25 10.6 1.5 0.44 9.8 0.1 2.1 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase HSP70 PF00012.20 GBG91219.1 - 8e-164 546.1 0.0 9.9e-164 545.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG91219.1 - 1.5e-14 53.6 0.1 1.1e-10 40.9 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG91219.1 - 0.00041 20.1 0.3 0.0011 18.7 0.3 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG91219.1 - 0.0014 19.0 0.0 0.55 10.7 0.0 2.9 2 2 0 2 2 2 2 Cell division protein FtsA HSP70 PF00012.20 GBG91221.1 - 1.7e-159 531.8 0.0 2.1e-159 531.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG91221.1 - 4.7e-09 35.5 0.0 3.7e-08 32.5 0.0 2.4 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG91221.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain CAP_N PF01213.19 GBG91221.1 - 3.4 7.1 3.9 5.3 6.4 3.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RT_RNaseH PF17917.1 GBG91222.1 - 3.7e-22 78.6 0.0 8.7e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91222.1 - 3.3e-21 75.2 0.0 8.4e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG91222.1 - 0.11 13.1 0.0 0.29 11.7 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF659 PF04937.15 GBG91223.1 - 0.00012 22.0 0.0 0.0003 20.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) CDC45 PF02724.14 GBG91223.1 - 5.4 5.2 8.3 7.3 4.7 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 GBG91224.1 - 2.2e-34 118.5 0.0 4.6e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91224.1 - 0.02 14.7 0.7 0.051 13.4 0.7 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region MGAT2 PF05060.14 GBG91225.1 - 9.2e-89 297.9 0.0 1.4e-88 297.3 0.0 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) RVT_1 PF00078.27 GBG91225.1 - 4.2e-28 98.4 0.0 6.7e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91225.1 - 3.1e-21 75.3 0.0 5.5e-16 58.4 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91225.1 - 9.6e-10 38.7 0.0 2.7e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HSP70 PF00012.20 GBG91226.1 - 1.5e-266 885.3 0.0 1.6e-124 416.3 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 GBG91226.1 - 5.2e-26 91.2 0.1 1.4e-13 50.4 0.0 3.3 4 0 0 4 4 4 2 MreB/Mbl protein FGGY_C PF02782.16 GBG91226.1 - 3.8e-05 23.5 0.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG91226.1 - 0.00042 20.7 1.4 14 6.1 0.5 5.2 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 GBG91226.1 - 0.00042 19.7 0.1 0.058 12.7 0.0 3.5 3 1 0 4 4 4 1 Hydantoinase/oxoprolinase StbA PF06406.11 GBG91226.1 - 0.046 12.9 2.2 1.6 7.9 0.2 3.3 2 2 1 3 3 3 0 StbA protein DUF963 PF06131.11 GBG91227.1 - 0.82 9.1 4.7 2.1 7.9 4.7 1.6 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) RVT_1 PF00078.27 GBG91228.1 - 1.3e-24 86.9 0.0 2.3e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG91228.1 - 2.1e-05 24.7 0.0 4.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Peptidase_S64 PF08192.11 GBG91230.1 - 2.1 6.8 7.3 2.8 6.3 7.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 RT_RNaseH_2 PF17919.1 GBG91232.1 - 3.6e-40 136.0 0.0 8.2e-26 90.0 0.0 3.7 2 1 1 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91232.1 - 3.5e-28 97.9 0.0 3.2e-21 75.6 0.0 3.8 2 1 1 3 3 3 3 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91232.1 - 1.9e-13 50.4 1.2 4.1e-07 29.7 0.0 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG91232.1 - 0.00088 19.5 10.6 0.028 14.7 0.0 5.4 4 0 0 4 4 4 1 Retrotransposon gag protein HXXSHH PF07586.11 GBG91232.1 - 0.016 14.8 7.1 0.06 12.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1552) Helo_like_N PF17111.5 GBG91232.1 - 0.028 13.8 4.4 1.5 8.1 0.1 3.7 3 1 0 3 3 3 0 Fungal N-terminal domain of STAND proteins CLZ PF16526.5 GBG91232.1 - 0.37 11.2 9.8 0.21 12.0 0.5 4.0 5 0 0 5 5 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tup_N PF08581.10 GBG91232.1 - 0.41 11.0 4.7 1.4 9.3 0.1 3.4 3 0 0 3 3 3 0 Tup N-terminal Syntaxin-6_N PF09177.11 GBG91232.1 - 0.59 10.7 7.2 35 5.0 0.0 4.4 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Leader_Trp PF08255.11 GBG91232.1 - 1.2 9.2 5.2 0.82 9.8 0.8 2.7 2 0 0 2 2 2 0 Trp-operon Leader Peptide PIEZO PF15917.5 GBG91232.1 - 1.8 8.0 8.3 20 4.5 6.0 2.3 2 0 0 2 2 2 0 Piezo Hemerythrin PF01814.23 GBG91233.1 - 0.018 15.7 1.0 0.063 13.9 0.2 2.4 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain Speriolin_N PF15058.6 GBG91233.1 - 0.065 13.3 0.2 0.099 12.7 0.2 1.3 1 0 0 1 1 1 0 Speriolin N terminus Mis14 PF08641.12 GBG91233.1 - 0.11 12.8 0.5 0.11 12.8 0.5 3.6 3 2 0 3 3 3 0 Kinetochore protein Mis14 like DUF5320 PF17253.2 GBG91233.1 - 0.23 12.6 1.9 4.3 8.5 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5320) DUF3987 PF13148.6 GBG91233.1 - 2 7.3 9.7 0.35 9.8 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3987) gag-asp_proteas PF13975.6 GBG91234.1 - 1.6e-06 28.6 0.0 5.9e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91234.1 - 1.8e-06 28.5 0.0 4.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG91234.1 - 1.2e-05 25.6 0.0 3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG91234.1 - 0.043 13.6 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease UPF0242 PF06785.11 GBG91236.1 - 0.076 13.1 12.3 0.14 12.2 12.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus VPS38 PF17649.1 GBG91236.1 - 6.5 5.5 9.1 11 4.8 9.1 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 rve PF00665.26 GBG91237.1 - 7.7e-11 42.2 0.1 1.3e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG91237.1 - 1e-05 25.3 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG91238.1 - 2.7e-34 117.2 0.0 5.1e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91238.1 - 3.5e-30 104.4 0.1 6.7e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91238.1 - 2.1e-27 96.1 0.0 3.7e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91238.1 - 8.2e-18 64.3 0.3 2e-17 63.1 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91238.1 - 1.3e-13 51.1 0.1 7e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Arfaptin PF06456.13 GBG91239.1 - 0.11 12.1 0.9 0.22 11.1 0.9 1.4 1 0 0 1 1 1 0 Arfaptin-like domain Retrotrans_gag PF03732.17 GBG91239.1 - 0.11 12.7 1.2 0.51 10.7 0.0 2.5 2 1 1 3 3 3 0 Retrotransposon gag protein Pkinase PF00069.25 GBG91240.1 - 1.8e-36 125.9 0.0 3.3e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91240.1 - 1.5e-33 116.2 0.0 2.2e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG91240.1 - 0.0079 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 GBG91240.1 - 0.2 11.2 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RT_RNaseH_2 PF17919.1 GBG91241.1 - 1e-32 112.1 0.0 2e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91241.1 - 2.8e-29 101.5 0.1 6.2e-29 100.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG91241.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein DUF1478 PF07349.11 GBG91241.1 - 0.091 12.7 0.0 19 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1478) ALS_ss_C PF10369.9 GBG91241.1 - 0.13 12.5 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Small subunit of acetolactate synthase DUF3306 PF11748.8 GBG91242.1 - 0.089 13.7 15.7 0.11 13.3 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) PTPRCAP PF15713.5 GBG91242.1 - 0.76 10.1 24.8 0.94 9.8 24.8 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RNA_pol_Rpc4 PF05132.14 GBG91242.1 - 0.88 10.0 7.1 1 9.8 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 GBG91242.1 - 1 8.1 7.4 1.1 8.0 7.4 1.0 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 GBG91242.1 - 2.7 8.1 23.3 4.1 7.5 23.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RPN2_C PF18004.1 GBG91242.1 - 3.2 7.7 18.9 4.4 7.2 18.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FYDLN_acid PF09538.10 GBG91242.1 - 3.3 8.4 17.5 4.9 7.9 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CobT PF06213.12 GBG91242.1 - 3.6 6.9 23.9 3.8 6.8 23.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 GBG91242.1 - 3.7 6.9 11.1 4.1 6.8 11.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nop14 PF04147.12 GBG91242.1 - 4.7 5.3 26.2 5.3 5.1 26.2 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 GBG91242.1 - 4.7 5.5 25.8 5.6 5.3 25.8 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF4366 PF14283.6 GBG91242.1 - 5.7 7.0 11.9 6.7 6.7 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Paf1 PF03985.13 GBG91242.1 - 5.8 5.8 27.5 6.4 5.7 27.5 1.1 1 0 0 1 1 1 0 Paf1 Pkinase PF00069.25 GBG91243.1 - 1.1e-37 129.8 0.0 2.1e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91243.1 - 9.6e-33 113.5 0.0 1.4e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG91243.1 - 0.0022 17.4 0.1 0.007 15.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Capsule_synth PF05159.14 GBG91243.1 - 0.013 14.9 0.0 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 Capsule polysaccharide biosynthesis protein RPW8 PF05659.11 GBG91243.1 - 0.023 14.4 0.3 0.023 14.4 0.3 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Beta-lactamase PF00144.24 GBG91244.1 - 2.2e-26 92.9 0.0 3.5e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase UPF0242 PF06785.11 GBG91245.1 - 0.014 15.5 15.6 0.014 15.5 15.6 3.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus zf-CCHC_2 PF13696.6 GBG91245.1 - 0.054 13.3 2.0 0.082 12.8 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle ARTD15_N PF18084.1 GBG91245.1 - 7.6 6.9 6.1 32 4.9 0.5 3.5 2 1 1 3 3 3 0 ARTD15 N-terminal domain Trypsin PF00089.26 GBG91246.1 - 3.3e-35 121.9 0.1 6.7e-35 120.9 0.1 1.5 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GBG91246.1 - 8.8e-05 23.4 0.9 0.00021 22.2 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain CPBP PF02517.16 GBG91247.1 - 1.1e-17 64.2 3.5 1.1e-17 64.2 3.5 2.3 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease ZapB PF06005.12 GBG91248.1 - 0.076 13.5 0.2 0.076 13.5 0.2 3.1 2 1 1 3 3 3 0 Cell division protein ZapB S-antigen PF05756.11 GBG91248.1 - 0.4 11.1 1.7 0.53 10.7 0.3 1.9 2 0 0 2 2 2 0 S-antigen protein Ribosomal_L31 PF01197.18 GBG91249.1 - 2.2e-17 63.0 0.2 3.3e-17 62.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L31 ID PF18543.1 GBG91249.1 - 0.0014 18.6 0.0 0.031 14.3 0.0 2.3 2 0 0 2 2 2 1 Intracellular delivery domain RT_RNaseH_2 PF17919.1 GBG91253.1 - 2.7e-32 110.8 0.0 5.6e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91253.1 - 4.9e-29 100.7 0.1 1.1e-28 99.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91253.1 - 2.4e-16 59.6 0.0 5.6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91253.1 - 1.7e-15 57.2 0.0 6.7e-15 55.3 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain DUF1564 PF07600.11 GBG91253.1 - 0.0024 17.6 0.0 0.0065 16.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) RGS12_us2 PF16611.5 GBG91253.1 - 0.11 13.0 1.0 0.41 11.1 1.0 2.1 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco Pkinase PF00069.25 GBG91254.1 - 1.6e-66 224.4 0.0 1.9e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91254.1 - 1e-30 106.9 0.0 1.9e-30 106.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG91254.1 - 5.3e-06 25.9 0.0 8.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 GBG91254.1 - 0.0012 18.5 0.3 0.0038 16.9 0.1 1.8 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GBG91254.1 - 0.0014 18.3 0.4 0.0025 17.4 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GBG91254.1 - 0.0015 18.0 0.2 0.0027 17.1 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GBG91254.1 - 0.093 11.5 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 GBG91255.1 - 1.3e-55 188.6 0.1 1.5e-55 188.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91255.1 - 5.8e-31 107.7 0.0 6.9e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG91255.1 - 2.4e-06 27.1 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 GBG91255.1 - 0.00032 20.4 0.4 0.0011 18.6 0.2 1.9 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GBG91255.1 - 0.00041 20.0 0.5 0.00063 19.4 0.5 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GBG91255.1 - 0.00067 19.1 0.8 0.0013 18.1 0.8 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GBG91255.1 - 0.039 12.7 0.1 0.065 12.0 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase RT_RNaseH PF17917.1 GBG91256.1 - 3e-30 104.6 0.0 8.5e-30 103.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91256.1 - 3.2e-30 104.1 0.0 8.7e-30 102.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91256.1 - 9.7e-20 70.4 0.4 2.5e-19 69.1 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91256.1 - 3.5e-16 59.5 0.0 9.7e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG91256.1 - 2.8e-07 30.3 0.3 0.00014 21.5 0.1 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG91256.1 - 0.00016 21.4 0.0 0.00036 20.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91256.1 - 0.00026 21.5 0.0 0.00058 20.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG91256.1 - 0.00029 21.0 0.1 0.0011 19.1 0.1 2.1 1 0 0 1 1 1 1 H2C2 zinc finger DUF1758 PF05585.12 GBG91256.1 - 0.0014 18.4 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 GBG91256.1 - 0.004 17.7 0.0 0.0093 16.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG91256.1 - 0.15 11.8 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Arc_PepC_II PF06847.11 GBG91256.1 - 1.8 9.2 4.1 37 4.9 1.3 3.9 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II FAM60A PF15396.6 GBG91256.1 - 3.2 7.7 7.7 6.8 6.6 7.7 1.5 1 0 0 1 1 1 0 Protein Family FAM60A CSRNP_N PF16019.5 GBG91256.1 - 4.3 7.2 6.7 9.5 6.1 6.7 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Retrotrans_gag PF03732.17 GBG91257.1 - 1.8e-07 31.3 5.9 0.044 14.1 0.1 4.5 3 2 1 4 4 4 3 Retrotransposon gag protein SlyX PF04102.12 GBG91257.1 - 0.3 11.7 9.0 8.2 7.1 0.0 3.7 3 0 0 3 3 3 0 SlyX PIEZO PF15917.5 GBG91257.1 - 0.38 10.2 5.1 0.66 9.4 5.1 1.3 1 0 0 1 1 1 0 Piezo RT_RNaseH_2 PF17919.1 GBG91258.1 - 4.2e-30 103.7 0.0 1.2e-29 102.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91258.1 - 2.7e-27 95.1 0.0 5.3e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91258.1 - 3.9e-14 52.7 0.1 5.7e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG91258.1 - 0.054 13.4 0.0 0.94 9.4 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Na_trans_assoc PF06512.13 GBG91258.1 - 0.67 10.2 14.9 1.1 9.5 14.9 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 GBG91258.1 - 1.7 7.9 18.6 2.3 7.5 18.6 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GBG91258.1 - 2.6 7.5 8.6 4.3 6.8 7.6 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 GBG91258.1 - 2.6 7.4 23.0 3.8 6.9 23.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG91258.1 - 2.6 6.1 20.0 3.4 5.8 20.0 1.1 1 0 0 1 1 1 0 Nop14-like family F-box_5 PF18511.1 GBG91259.1 - 4.9e-05 22.8 0.1 0.00013 21.4 0.1 1.7 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 GBG91259.1 - 0.0089 15.9 0.1 0.0089 15.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like DDE_Tnp_4 PF13359.6 GBG91260.1 - 7.8e-27 93.9 0.0 1.5e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91260.1 - 8.1e-14 51.7 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91260.1 - 0.0015 18.2 0.2 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG91260.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain LapA_dom PF06305.11 GBG91261.1 - 0.0057 16.4 0.5 0.0091 15.8 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Myb_DNA-bind_4 PF13837.6 GBG91261.1 - 0.007 16.7 1.1 0.012 16.0 1.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain T2SSM PF04612.12 GBG91261.1 - 0.0095 16.0 0.2 0.019 15.1 0.2 1.4 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M YajC PF02699.15 GBG91261.1 - 0.09 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit TAS2R PF05296.13 GBG91261.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) DUF1461 PF07314.11 GBG91261.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Comm PF15957.5 GBG91261.1 - 0.22 11.8 0.0 0.4 11.0 0.0 1.3 1 0 0 1 1 1 0 Commissureless Prominin PF05478.11 GBG91261.1 - 0.35 8.8 0.0 0.45 8.4 0.0 1.0 1 0 0 1 1 1 0 Prominin Myb_DNA-bind_4 PF13837.6 GBG91264.1 - 9e-08 32.4 1.3 9e-08 32.4 1.3 2.7 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG91265.1 - 5.7e-30 104.1 0.0 4e-29 101.3 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91265.1 - 1.2e-12 47.9 0.0 1.9e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91265.1 - 0.0052 16.4 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 1 Transposase DDE domain DUF4235 PF14019.6 GBG91267.1 - 0.039 14.0 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) RVT_1 PF00078.27 GBG91271.1 - 4.1e-29 101.7 0.0 8.1e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91271.1 - 3.7e-26 91.1 0.3 8.3e-26 90.0 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91271.1 - 1.1e-23 83.5 0.3 2.6e-23 82.3 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG91271.1 - 6.7e-12 45.6 0.1 3.9e-11 43.2 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain DUF5095 PF17016.5 GBG91271.1 - 0.056 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) EAP30 PF04157.16 GBG91271.1 - 0.18 11.1 0.4 0.37 10.0 0.4 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family DUF1751 PF08551.10 GBG91272.1 - 2.7e-22 79.2 1.5 2.7e-22 79.2 1.5 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 GBG91272.1 - 1.2e-05 25.4 2.8 2e-05 24.6 2.8 1.4 1 0 0 1 1 1 1 Rhomboid family Integrase_H2C2 PF17921.1 GBG91274.1 - 4.7e-19 68.2 1.1 1.2e-18 67.0 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91274.1 - 3.7e-16 59.4 0.0 8.1e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91274.1 - 0.028 14.6 0.3 0.057 13.6 0.3 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Arm PF00514.23 GBG91275.1 - 0.094 12.8 4.0 0.58 10.3 0.3 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat BSP_II PF05432.11 GBG91276.1 - 0.18 11.4 22.0 1.4 8.5 17.3 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.10 GBG91276.1 - 5.5 7.4 26.9 10 6.5 0.3 3.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Spc7 PF08317.11 GBG91278.1 - 0.0036 16.2 1.0 0.0036 16.2 1.0 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Filament PF00038.21 GBG91278.1 - 0.022 14.4 5.7 0.7 9.4 1.9 2.2 2 0 0 2 2 2 0 Intermediate filament protein Taxilin PF09728.9 GBG91278.1 - 0.028 13.6 6.2 0.87 8.7 1.4 2.2 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DASH_Dad4 PF08650.10 GBG91278.1 - 0.034 14.1 0.5 0.11 12.5 0.2 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad4 FPP PF05911.11 GBG91278.1 - 0.069 11.3 2.0 0.099 10.8 2.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 GBG91278.1 - 0.071 13.3 8.5 0.17 12.1 8.5 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 GBG91278.1 - 0.094 12.1 7.7 0.17 11.2 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 GBG91278.1 - 0.11 13.2 1.9 0.94 10.1 0.2 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Prefoldin PF02996.17 GBG91278.1 - 0.21 11.5 2.8 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.8 GBG91278.1 - 0.3 11.3 10.6 0.17 12.1 4.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HAUS-augmin3 PF14932.6 GBG91278.1 - 0.35 10.4 4.8 0.046 13.3 0.6 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 GBG91278.1 - 0.44 10.6 10.6 0.53 10.3 2.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 GBG91278.1 - 0.65 10.3 5.9 1.3 9.3 1.4 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.11 GBG91278.1 - 0.68 10.0 6.8 2.2 8.4 0.7 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase YlqD PF11068.8 GBG91278.1 - 0.69 10.3 3.0 1.3 9.4 0.3 2.2 2 0 0 2 2 2 0 YlqD protein APG6_N PF17675.1 GBG91278.1 - 0.87 10.1 10.6 2.6 8.6 10.6 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 GBG91278.1 - 1.4 9.3 7.5 0.34 11.3 1.2 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.12 GBG91278.1 - 1.5 9.3 12.7 8.4 6.9 0.3 2.6 2 0 0 2 2 2 0 Cell division protein ZapB DUF2968 PF11180.8 GBG91278.1 - 1.7 8.2 7.1 2.2 7.9 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) ADIP PF11559.8 GBG91278.1 - 2.3 8.3 10.4 0.91 9.6 2.2 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Trimer_CC PF08954.11 GBG91278.1 - 2.6 7.7 10.3 0.4 10.3 1.2 2.7 2 0 0 2 2 2 0 Trimerisation motif GAS PF13851.6 GBG91278.1 - 2.7 7.3 6.8 6.6 6.0 1.7 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FlxA PF14282.6 GBG91278.1 - 3 7.9 5.7 2.5 8.1 0.5 2.4 2 1 1 3 3 3 0 FlxA-like protein HALZ PF02183.18 GBG91278.1 - 3.3 8.0 10.8 10 6.5 0.4 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper SlyX PF04102.12 GBG91278.1 - 4.4 8.0 9.7 16 6.2 0.4 2.7 2 0 0 2 2 2 0 SlyX Golgin_A5 PF09787.9 GBG91278.1 - 4.5 6.6 13.4 1.1 8.6 5.9 2.2 1 1 0 2 2 2 0 Golgin subfamily A member 5 TSC22 PF01166.18 GBG91278.1 - 6.9 7.1 7.0 20 5.6 0.9 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4140 PF13600.6 GBG91278.1 - 9.9 6.7 11.6 29 5.2 5.7 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4360 PF14273.6 GBG91280.1 - 1.5e-35 122.7 0.0 1.7e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF659 PF04937.15 GBG91281.1 - 1.4e-33 115.9 0.2 3.9e-33 114.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DUF755 PF05501.11 GBG91281.1 - 2.7 8.3 7.6 5.4 7.3 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4360 PF14273.6 GBG91282.1 - 9.9e-33 113.5 0.0 1.1e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) REV PF00424.18 GBG91283.1 - 0.028 14.4 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DDRGK PF09756.9 GBG91283.1 - 0.16 11.5 21.3 0.2 11.2 21.3 1.1 1 0 0 1 1 1 0 DDRGK domain DUF1943 PF09172.11 GBG91283.1 - 0.41 9.8 6.3 0.47 9.7 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) PA26 PF04636.13 GBG91283.1 - 0.67 8.8 11.3 0.74 8.7 11.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TP53IP5 PF15331.6 GBG91283.1 - 0.91 9.6 12.9 0.96 9.6 12.9 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF2201_N PF13203.6 GBG91283.1 - 3.3 7.2 11.5 3.9 7.0 11.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3810 PF12725.7 GBG91283.1 - 4.2 6.6 5.5 4.7 6.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Hid1 PF12722.7 GBG91283.1 - 6.3 4.8 10.8 7.2 4.6 10.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4360 PF14273.6 GBG91284.1 - 2.5e-35 122.0 0.0 2.9e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DIM PF08194.12 GBG91284.1 - 0.019 15.2 3.8 0.048 13.9 3.8 1.7 1 1 0 1 1 1 0 DIM protein DUF4360 PF14273.6 GBG91285.1 - 1.1e-38 132.9 0.0 1.3e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MscS_TM PF12794.7 GBG91287.1 - 0.26 10.1 0.1 0.26 10.1 0.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Macoilin PF09726.9 GBG91287.1 - 0.86 8.1 6.7 0.039 12.5 0.5 1.7 2 0 0 2 2 2 0 Macoilin family ABATE PF07336.11 GBG91287.1 - 8.2 7.1 18.0 1.2 9.8 0.7 2.3 1 1 1 2 2 2 0 Putative stress-induced transcription regulator Cellulose_synt PF03552.14 GBG91288.1 - 0 1153.5 0.3 0 1153.0 0.3 1.1 1 0 0 1 1 1 1 Cellulose synthase zf-UDP PF14569.6 GBG91288.1 - 4.2e-17 62.0 4.9 1.3e-16 60.5 4.9 1.8 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 GBG91288.1 - 4.9e-10 39.0 10.1 4.9e-10 39.0 10.1 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Glyco_trans_2_3 PF13632.6 GBG91288.1 - 2.3e-06 27.7 0.4 2.3e-06 27.7 0.4 3.1 3 0 0 3 3 3 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GBG91288.1 - 0.00021 21.2 0.0 0.00059 19.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 RVT_1 PF00078.27 GBG91289.1 - 2.2e-36 125.5 0.0 4.1e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91289.1 - 3.3e-29 101.2 0.1 6.4e-29 100.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91289.1 - 2.7e-28 97.9 0.0 5.8e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91289.1 - 1.4e-18 66.7 1.0 2.8e-18 65.8 1.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91289.1 - 8.5e-05 22.7 0.0 0.00022 21.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91289.1 - 0.002 18.3 0.0 0.0074 16.5 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Phage_GPO PF05929.11 GBG91289.1 - 0.18 11.4 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_int_SAM_1 PF02899.17 GBG91291.1 - 0.014 15.7 0.3 0.031 14.6 0.3 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain gag-asp_proteas PF13975.6 GBG91291.1 - 0.02 15.5 0.0 0.054 14.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91291.1 - 0.12 13.0 0.0 0.36 11.5 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DDE_Tnp_4 PF13359.6 GBG91292.1 - 1.8e-29 102.4 0.0 3.3e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF659 PF04937.15 GBG91292.1 - 7.4e-27 94.1 0.8 1e-26 93.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Plant_tran PF04827.14 GBG91292.1 - 4.7e-11 42.7 0.0 8.8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91292.1 - 0.021 14.4 0.2 1.4 8.5 0.2 2.9 3 0 0 3 3 3 0 Transposase DDE domain PGI PF00342.19 GBG91293.1 - 6e-210 697.9 0.0 6.8e-210 697.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DnaJ_CXXCXGXG PF00684.19 GBG91295.1 - 3e-05 24.3 0.2 6.9e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 DnaJ central domain zinc_ribbon_9 PF14369.6 GBG91295.1 - 0.0023 18.1 0.4 0.25 11.7 0.1 2.6 2 0 0 2 2 2 1 zinc-ribbon Anti-TRAP PF15777.5 GBG91295.1 - 0.2 11.6 1.4 8.6 6.4 0.1 2.4 1 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TFR_dimer PF04253.15 GBG91296.1 - 1.8e-17 63.5 0.0 2e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Myb_DNA-binding PF00249.31 GBG91296.1 - 0.14 12.4 0.2 0.28 11.4 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain RVP_2 PF08284.11 GBG91297.1 - 1.3e-09 37.9 0.0 3.2e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91297.1 - 3.1e-08 34.1 0.0 8.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91297.1 - 2.2e-06 28.2 0.0 7e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG91297.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG91297.1 - 0.52 10.6 6.7 0.088 13.1 0.4 3.0 4 0 0 4 4 4 0 Retrotransposon gag protein FAM76 PF16046.5 GBG91297.1 - 0.67 9.2 8.9 1.2 8.5 8.9 1.3 1 0 0 1 1 1 0 FAM76 protein RT_RNaseH_2 PF17919.1 GBG91298.1 - 2.8e-27 94.7 0.0 5.7e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91298.1 - 2e-24 85.8 0.0 5.1e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91298.1 - 1.9e-17 63.1 0.1 4.9e-17 61.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG91298.1 - 2.2e-14 53.5 0.0 4.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG91298.1 - 1e-09 38.6 0.0 3.7e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG91298.1 - 3.9e-08 33.8 0.0 9.1e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91298.1 - 2.2e-07 31.4 0.0 5.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG91298.1 - 2.3e-06 27.4 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG91298.1 - 1.5e-05 24.7 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG91298.1 - 0.0023 18.1 0.1 0.0073 16.5 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG91299.1 - 3.5e-47 158.5 0.0 6.7e-23 80.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91299.1 - 9.6e-46 154.4 0.0 8.9e-22 77.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91299.1 - 6.7e-34 115.8 7.1 5.3e-17 61.7 0.3 3.1 3 0 0 3 3 3 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG91299.1 - 1.3e-32 113.2 0.0 5.9e-20 71.7 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M28 PF04389.17 GBG91299.1 - 6.7e-21 74.9 0.0 3.9e-20 72.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M28 rve PF00665.26 GBG91299.1 - 1.1e-10 41.7 0.0 1.5e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain PA PF02225.22 GBG91299.1 - 6.3e-08 32.5 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-H2C2 PF09337.10 GBG91299.1 - 4e-06 27.0 2.6 0.01 16.0 0.1 2.8 2 0 0 2 2 2 2 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG91299.1 - 9.9e-05 22.9 0.0 0.00022 21.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91299.1 - 0.00054 20.5 0.0 0.0014 19.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Nicastrin PF05450.15 GBG91299.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.28 GBG91299.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 zf-CCHC PF00098.23 GBG91299.1 - 0.026 14.6 2.5 0.069 13.3 2.5 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG91300.1 - 1.2e-29 103.4 0.1 4.9e-29 101.4 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DnaJ PF00226.31 GBG91300.1 - 1.1e-09 38.3 0.2 3.2e-09 36.8 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain Asp_protease_2 PF13650.6 GBG91300.1 - 9.3e-08 32.6 0.0 3.1e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91300.1 - 5.9e-07 30.0 0.0 1.8e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG91300.1 - 6.7e-06 25.9 0.0 3e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG91300.1 - 0.00079 19.2 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG91300.1 - 0.002 18.3 0.1 0.002 18.3 0.1 3.5 4 0 0 4 4 3 1 Retrotransposon gag protein SPACA9 PF15120.6 GBG91300.1 - 0.0083 15.9 1.0 0.023 14.5 1.0 1.8 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 BLOC1_2 PF10046.9 GBG91300.1 - 0.25 11.7 6.4 0.24 11.7 2.4 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1068 PF06364.12 GBG91300.1 - 0.37 10.6 5.8 0.33 10.8 4.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) Syntaxin-6_N PF09177.11 GBG91300.1 - 1.4 9.5 4.7 1.2 9.7 0.8 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 GBG91300.1 - 4.1 7.9 6.5 36 4.9 0.9 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 GBG91300.1 - 7.4 6.6 5.7 0.93 9.5 1.1 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 GBG91300.1 - 8.3 7.1 22.5 0.047 14.3 6.6 3.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RVT_1 PF00078.27 GBG91302.1 - 3.3e-31 108.5 0.1 6.1e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91302.1 - 1.4e-30 105.3 0.0 4.6e-30 103.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91302.1 - 5.5e-18 65.2 0.0 1.5e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG91304.1 - 6.6e-34 117.0 0.0 1.3e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG91304.1 - 2.6e-19 69.4 0.0 5.8e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91304.1 - 1.3e-15 57.3 0.0 1.3e-15 57.3 0.0 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG91304.1 - 2.9e-13 49.7 0.0 5.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG91304.1 - 4.7e-06 26.8 0.0 2.4e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG91304.1 - 2.4e-05 24.4 0.0 6.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-BED PF02892.15 GBG91304.1 - 0.05 13.6 1.1 0.21 11.7 0.5 2.3 2 0 0 2 2 2 0 BED zinc finger RRM_1 PF00076.22 GBG91306.1 - 3.3e-48 161.4 0.0 2.9e-15 55.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG91306.1 - 7.9e-07 29.1 0.1 0.026 14.6 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 GBG91306.1 - 1.8e-05 24.3 0.0 0.024 14.3 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GBG91306.1 - 8e-05 22.6 0.0 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 GBG91306.1 - 0.0036 17.3 0.0 0.018 15.0 0.0 2.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 GBG91306.1 - 0.14 11.8 0.5 22 4.8 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain Myb_DNA-bind_4 PF13837.6 GBG91307.1 - 1.5e-07 31.7 2.9 3.2e-07 30.6 1.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91307.1 - 0.00011 22.4 2.0 0.0013 19.0 0.3 2.6 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG91307.1 - 0.12 12.5 0.4 0.28 11.3 0.4 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG91308.1 - 2.9e-07 30.3 1.5 3.5e-06 26.8 0.0 2.7 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91308.1 - 1.7e-05 24.5 0.0 0.005 16.5 0.0 2.2 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG91308.1 - 0.011 16.1 0.1 0.028 14.8 0.1 1.7 1 0 0 1 1 1 0 Transposase DDE domain PI_PP_C PF18365.1 GBG91310.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain Glyco_trans_2_3 PF13632.6 GBG91311.1 - 3.4e-20 72.8 4.9 3.4e-20 72.8 4.9 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GBG91311.1 - 5.2e-20 72.3 0.0 7.5e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GBG91311.1 - 3.6e-13 49.7 0.0 6.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 LT-IIB PF06453.11 GBG91311.1 - 0.19 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) DBD_Tnp_Hermes PF10683.9 GBG91313.1 - 1.8e-05 24.3 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain RT_RNaseH_2 PF17919.1 GBG91314.1 - 4.1e-15 55.6 0.0 8.2e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91314.1 - 2.5e-11 43.8 0.0 7.2e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91314.1 - 1.2e-10 41.3 0.7 3.2e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG91314.1 - 0.0017 18.8 0.0 0.0044 17.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG91314.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG91315.1 - 0.0016 18.9 0.1 0.0048 17.4 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91315.1 - 0.018 15.7 0.0 0.062 14.0 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG91315.1 - 0.047 14.0 0.2 0.25 11.6 0.1 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 GBG91315.1 - 0.098 13.0 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG91317.1 - 2.3e-08 34.0 0.0 4.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91317.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 GBG91318.1 - 1e-05 26.0 0.1 5.6e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91318.1 - 0.0027 18.3 0.1 0.014 16.1 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Nucleo_P87 PF07267.11 GBG91318.1 - 2.5 6.8 3.4 5.9 5.6 3.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 rve PF00665.26 GBG91319.1 - 5e-15 55.7 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG91319.1 - 7.8e-14 51.5 0.1 2.9e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG91319.1 - 1.3e-05 25.4 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91319.1 - 7.3e-05 22.7 0.1 0.00014 21.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 GBG91319.1 - 0.034 13.9 0.3 0.17 11.7 0.0 2.3 3 0 0 3 3 3 0 Integrase core domain SAM_KSR1 PF13543.6 GBG91320.1 - 0.075 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 RT_RNaseH PF17917.1 GBG91321.1 - 6.1e-24 84.3 0.1 1.1e-22 80.2 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91321.1 - 7.1e-17 61.3 0.0 2.4e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG91321.1 - 1.4e-08 34.9 10.6 0.0008 19.6 0.1 4.4 4 0 0 4 4 4 2 Retrotransposon gag protein rve PF00665.26 GBG91321.1 - 1.6e-08 34.8 0.1 8.7e-08 32.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain CAMP_factor PF07373.11 GBG91321.1 - 0.0092 15.6 1.5 0.025 14.2 0.4 2.4 2 0 0 2 2 2 1 CAMP factor (Cfa) HIP1_clath_bdg PF16515.5 GBG91321.1 - 0.0097 16.5 1.8 0.0097 16.5 1.8 5.2 6 0 0 6 6 6 1 Clathrin-binding domain of Huntingtin-interacting protein 1 BLOC1_2 PF10046.9 GBG91321.1 - 2.8 8.3 16.3 0.35 11.2 1.6 4.0 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GIT_CC PF16559.5 GBG91321.1 - 3 7.8 5.9 16 5.5 0.1 3.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF16 PF01519.16 GBG91321.1 - 3.4 8.2 6.5 4.5 7.8 0.7 3.4 3 0 0 3 3 3 0 Protein of unknown function DUF16 COG5 PF10392.9 GBG91321.1 - 9.6 6.4 8.4 9.3 6.4 0.6 3.3 2 1 1 3 3 3 0 Golgi transport complex subunit 5 NPDC1 PF06809.11 GBG91322.1 - 2.1 7.3 3.5 3.1 6.8 3.5 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) DDE_Tnp_4 PF13359.6 GBG91323.1 - 1.3e-31 109.4 0.0 2.2e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91323.1 - 2.5e-14 53.4 0.0 4.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91323.1 - 0.00013 21.7 0.1 0.33 10.6 0.0 3.1 3 0 0 3 3 3 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG91324.1 - 3.1e-07 30.7 0.4 4.7e-06 26.9 0.3 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG91324.1 - 0.0015 18.6 0.2 0.0042 17.1 0.2 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Mucin-like PF16058.5 GBG91326.1 - 7.8e-06 25.9 12.5 1.4e-05 25.1 12.1 1.5 1 1 0 1 1 1 1 Mucin-like PHD_Oberon PF07227.11 GBG91327.1 - 8.2e-16 58.1 28.6 8.2e-16 58.1 28.6 1.5 2 0 0 2 2 2 1 PHD - plant homeodomain finger protein RT_RNaseH_2 PF17919.1 GBG91328.1 - 2.4e-31 107.7 0.1 8e-31 106.0 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91328.1 - 5.4e-27 94.1 0.7 1.6e-26 92.6 0.4 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91328.1 - 5.5e-25 88.2 0.1 9.6e-25 87.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91328.1 - 2.9e-10 40.1 0.0 9.5e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain DUF2584 PF10763.9 GBG91328.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) Fzo_mitofusin PF04799.13 GBG91329.1 - 0.0016 18.0 9.0 0.14 11.7 1.0 2.1 1 1 1 2 2 2 2 fzo-like conserved region Prefoldin_2 PF01920.20 GBG91329.1 - 0.049 13.6 2.5 0.049 13.6 2.5 3.1 2 1 0 3 3 3 0 Prefoldin subunit MerR-DNA-bind PF09278.11 GBG91329.1 - 0.095 13.2 2.7 3 8.5 0.3 2.4 2 0 0 2 2 2 0 MerR, DNA binding CLZ PF16526.5 GBG91329.1 - 0.2 12.0 0.4 0.2 12.0 0.4 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3080 PF11279.8 GBG91329.1 - 0.21 10.8 6.8 0.24 10.6 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) DUF5595 PF18077.1 GBG91329.1 - 0.62 10.2 10.6 1.6 8.8 2.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) CRR7 PF12095.8 GBG91329.1 - 2.5 8.6 5.5 11 6.5 0.3 2.3 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 CENP-Q PF13094.6 GBG91329.1 - 3.1 8.0 19.1 0.24 11.6 4.9 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GDA1_CD39 PF01150.17 GBG91332.1 - 1.2e-96 324.0 0.0 1.6e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 GBG91332.1 - 0.024 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF913 PF06025.12 GBG91333.1 - 0.32 9.9 1.1 0.37 9.7 1.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RT_RNaseH_2 PF17919.1 GBG91334.1 - 4.9e-27 93.9 0.0 8.1e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91334.1 - 1.2e-23 83.4 0.0 2e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91334.1 - 6.8e-10 38.8 0.0 1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTPRCAP PF15713.5 GBG91334.1 - 0.17 12.2 11.9 0.31 11.3 11.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG91334.1 - 0.23 9.7 11.4 0.34 9.2 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG91334.1 - 0.57 8.3 9.6 0.72 8.0 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG91334.1 - 0.74 9.2 10.6 0.98 8.8 10.6 1.1 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 GBG91335.1 - 2.2 7.9 9.3 9.2 5.9 2.0 3.0 2 0 0 2 2 2 0 FAM176 family TPR_2 PF07719.17 GBG91336.1 - 4.4e-11 42.0 0.0 0.0054 16.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GBG91336.1 - 6.3e-07 29.0 0.0 0.0041 16.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG91336.1 - 5.2e-06 26.9 0.3 0.0021 18.5 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG91336.1 - 8.7e-05 23.0 7.4 0.0027 18.4 0.4 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GBG91336.1 - 9.2e-05 22.4 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GBG91336.1 - 0.0017 18.3 0.0 0.065 13.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG91336.1 - 0.0052 16.4 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 GBG91336.1 - 0.023 15.3 13.9 0.33 11.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG91336.1 - 0.025 14.9 0.0 6.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 GBG91336.1 - 0.12 12.8 0.1 21 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 GBG91336.1 - 0.5 10.6 5.7 5.6 7.2 0.0 3.5 3 0 0 3 3 3 0 HemY protein N-terminus 2Fe-2S_thioredx PF01257.19 GBG91336.1 - 1.3 8.8 2.7 3.7 7.4 2.7 1.7 1 1 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin RVT_1 PF00078.27 GBG91337.1 - 8e-39 133.4 0.0 1.2e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.6 GBG91338.1 - 0.00016 22.0 2.2 0.00016 22.0 0.9 1.8 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG91338.1 - 0.022 14.8 1.4 0.024 14.7 0.4 1.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Choline_kinase PF01633.20 GBG91340.1 - 5.1e-54 183.1 0.0 1.1e-53 182.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GBG91340.1 - 1.1e-07 32.1 2.5 2.2e-05 24.5 0.1 2.5 2 1 0 2 2 2 2 Phosphotransferase enzyme family Secretin_N_2 PF07655.13 GBG91340.1 - 0.15 12.6 4.8 0.38 11.3 4.8 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Mlh1_C PF16413.5 GBG91340.1 - 0.86 8.9 3.2 0.49 9.7 0.4 1.8 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus BRF1 PF07741.13 GBG91340.1 - 1.5 9.2 11.9 2.6 8.5 7.5 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF4366 PF14283.6 GBG91341.1 - 0.78 9.8 12.5 0.23 11.5 7.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) RNA_pol_3_Rpc31 PF11705.8 GBG91341.1 - 1 9.5 32.6 0.53 10.5 19.5 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 GBG91341.1 - 1.7 7.9 19.9 2.1 7.6 12.1 2.1 2 0 0 2 2 2 0 NOA36 protein TRAP_alpha PF03896.16 GBG91341.1 - 2.4 7.3 18.0 0.36 10.0 9.9 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 GBG91341.1 - 2.6 7.3 22.6 3.7 6.8 22.6 1.2 1 0 0 1 1 1 0 BUD22 Prothymosin PF03247.14 GBG91341.1 - 4.2 7.9 47.0 3.7 8.1 29.0 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family TFIIF_alpha PF05793.12 GBG91341.1 - 5.9 5.4 39.4 7.2 5.1 39.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3306 PF11748.8 GBG91341.1 - 7 7.5 12.2 1.5 9.7 6.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Pox_Ag35 PF03286.14 GBG91341.1 - 7.3 6.3 18.9 1.3 8.8 10.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Zip PF02535.22 GBG91341.1 - 7.7 5.6 6.9 0.43 9.7 1.9 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3292 PF11696.8 GBG91341.1 - 8.4 4.6 8.0 4.1 5.6 6.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) CDC27 PF09507.10 GBG91341.1 - 9.5 5.5 24.5 13 5.1 24.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDE_Tnp_4 PF13359.6 GBG91344.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease SDA1 PF05285.12 GBG91344.1 - 0.37 10.2 13.7 0.51 9.7 13.7 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG91344.1 - 0.45 8.7 10.6 0.63 8.3 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG91344.1 - 0.48 10.5 16.5 0.76 9.8 16.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GBG91344.1 - 1.3 7.2 15.1 1.7 6.8 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GBG91344.1 - 4.3 7.0 13.5 6.6 6.4 13.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RVT_1 PF00078.27 GBG91345.1 - 1.1e-18 67.6 0.1 1.6e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91345.1 - 0.0019 18.8 0.0 0.0043 17.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG91348.1 - 9.9e-06 25.4 1.4 1.6e-05 24.8 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG91348.1 - 0.021 14.6 1.1 0.043 13.6 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 GBG91348.1 - 0.036 13.9 0.5 0.15 12.0 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG91348.1 - 0.041 13.9 0.1 0.092 12.7 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Pox_A11 PF05061.13 GBG91348.1 - 2.5 7.3 7.7 5.5 6.2 1.1 2.9 2 1 0 3 3 3 0 Poxvirus A11 Protein CDC45 PF02724.14 GBG91349.1 - 0.37 9.0 3.9 0.37 9.0 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH PF17917.1 GBG91350.1 - 5.1e-26 91.0 0.0 1.2e-25 89.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91350.1 - 4.9e-21 74.6 0.0 1e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91350.1 - 2.8e-14 52.9 0.1 2.5e-13 49.9 0.1 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG91350.1 - 4.4e-08 33.3 0.0 9.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain CCDC85 PF10226.9 GBG91350.1 - 0.0072 16.0 0.4 0.016 14.9 0.4 1.5 1 0 0 1 1 1 1 CCDC85 family eIF-1a PF01176.19 GBG91350.1 - 0.023 14.5 0.2 0.076 12.8 0.1 1.9 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 DUF2385 PF09539.10 GBG91350.1 - 0.07 13.7 0.1 1.5 9.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) zf-H2C2 PF09337.10 GBG91350.1 - 0.13 12.5 0.0 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger tRNA_lig_CPD PF08302.11 GBG91350.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Chromo PF00385.24 GBG91350.1 - 0.14 12.0 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ABC_tran_CTD PF16326.5 GBG91350.1 - 0.49 10.7 4.6 0.25 11.6 1.0 2.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain bZIP_2 PF07716.15 GBG91350.1 - 0.76 9.9 3.6 1.9 8.7 3.6 1.7 1 0 0 1 1 1 0 Basic region leucine zipper GIT_CC PF16559.5 GBG91350.1 - 0.87 9.5 3.0 2.6 8.0 3.0 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ARGLU PF15346.6 GBG91351.1 - 0.00014 21.7 16.7 0.035 14.0 9.4 2.3 2 0 0 2 2 2 2 Arginine and glutamate-rich 1 CTU2 PF10288.9 GBG91351.1 - 5.6 7.2 15.9 0.7 10.1 3.4 2.6 2 2 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 A_thal_3526 PF09713.10 GBG91353.1 - 5.3e-25 87.4 0.5 8.4e-25 86.8 0.5 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) betaPIX_CC PF16523.5 GBG91354.1 - 0.028 14.2 1.0 0.063 13.1 0.2 2.0 2 0 0 2 2 2 0 betaPIX coiled coil Vps5 PF09325.10 GBG91354.1 - 0.074 12.6 2.8 0.25 10.9 0.2 2.2 1 1 1 2 2 2 0 Vps5 C terminal like MRP-S26 PF14943.6 GBG91354.1 - 0.079 12.9 0.1 0.079 12.9 0.1 2.2 2 1 0 2 2 2 0 Mitochondrial ribosome subunit S26 DMPK_coil PF08826.10 GBG91354.1 - 0.19 11.8 3.9 0.19 11.9 1.0 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Serpin PF00079.20 GBG91355.1 - 2e-97 326.9 0.0 2.2e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 GBG91356.1 - 1.1e-94 317.8 0.0 1.2e-94 317.7 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF659 PF04937.15 GBG91357.1 - 2.2e-05 24.4 0.0 3.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SDH_beta PF03315.15 GBG91357.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Serine dehydratase beta chain Dimer_Tnp_hAT PF05699.14 GBG91357.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region GTP_cyclohydroI PF01227.22 GBG91358.1 - 0.12 11.8 1.1 0.28 10.6 0.5 1.9 2 0 0 2 2 2 0 GTP cyclohydrolase I Serpin PF00079.20 GBG91360.1 - 7.5e-96 321.7 0.0 8.9e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) RT_RNaseH_2 PF17919.1 GBG91361.1 - 1.6e-29 101.8 0.0 7.8e-16 58.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91361.1 - 2.4e-27 95.3 0.0 4.9e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91361.1 - 5.8e-17 61.5 0.1 2.8e-16 59.4 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG91361.1 - 2.5e-13 50.3 0.1 1.4e-12 47.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG91361.1 - 3.3e-11 43.1 0.3 5.4e-11 42.4 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG91361.1 - 0.0003 20.9 0.0 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Serpin PF00079.20 GBG91362.1 - 1.3e-95 320.8 0.0 1.8e-95 320.4 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Abhydrolase_1 PF00561.20 GBG91363.1 - 1.3e-20 74.2 0.8 2.3e-19 70.0 0.1 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG91363.1 - 4.4e-16 58.9 0.1 2.7e-15 56.3 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG91363.1 - 2.9e-11 44.4 0.9 4.9e-11 43.7 0.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 GBG91363.1 - 1.4e-05 25.3 0.3 0.0055 16.8 0.2 2.3 2 0 0 2 2 2 2 Thioesterase domain Esterase PF00756.20 GBG91363.1 - 0.0056 16.4 0.2 0.013 15.2 0.2 1.6 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 GBG91363.1 - 0.039 13.7 0.3 0.43 10.3 0.6 2.3 2 1 1 3 3 3 0 PGAP1-like protein Ndr PF03096.14 GBG91363.1 - 0.16 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Ammonium_transp PF00909.21 GBG91364.1 - 1e-62 212.2 27.2 1.2e-62 211.9 27.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RVT_1 PF00078.27 GBG91365.1 - 3e-12 46.5 0.0 3.7e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG91366.1 - 6.1e-24 84.8 0.0 1e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG91366.1 - 2.1e-07 30.8 0.0 5.1e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91366.1 - 3.2e-07 30.9 0.0 7.8e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91366.1 - 7.1e-05 23.3 0.0 0.00016 22.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG91366.1 - 0.00072 19.8 0.1 0.003 17.8 0.1 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG91366.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG91366.1 - 0.034 14.8 0.3 0.034 14.8 0.3 3.3 5 1 0 5 5 5 0 SlyX CENP-F_leu_zip PF10473.9 GBG91366.1 - 0.7 9.9 2.9 4.3 7.4 2.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 GBG91366.1 - 1.2 9.3 4.3 1.8 8.7 3.1 1.9 1 1 1 2 2 2 0 TolA binding protein trimerisation JIP_LZII PF16471.5 GBG91366.1 - 10 6.4 6.3 8 6.7 1.9 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II RVT_1 PF00078.27 GBG91367.1 - 1.3e-26 93.5 0.2 2.9e-26 92.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91367.1 - 1.6e-22 79.4 0.0 2.9e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91367.1 - 2.7e-22 79.0 0.0 4.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91367.1 - 3.8e-17 62.1 0.0 8.2e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG91367.1 - 1.6e-07 31.8 0.0 3.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91367.1 - 9.3e-06 26.1 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG91367.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG91367.1 - 4e-05 23.8 0.0 0.00022 21.4 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG91367.1 - 0.00089 19.0 0.0 0.0027 17.5 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG91367.1 - 0.085 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Retrotrans_gag PF03732.17 GBG91368.1 - 5.1e-05 23.5 0.1 5.1e-05 23.5 0.1 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein T4SS PF07996.11 GBG91368.1 - 0.029 14.8 2.7 0.054 13.9 2.7 1.4 1 0 0 1 1 1 0 Type IV secretion system proteins HSBP1 PF06825.12 GBG91368.1 - 0.041 13.7 1.5 0.093 12.6 0.1 2.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 CAMP_factor PF07373.11 GBG91368.1 - 0.089 12.4 0.2 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 CAMP factor (Cfa) PP2C PF00481.21 GBG91369.1 - 2.7e-34 119.0 0.0 4.1e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C ACTH_assoc PF16102.5 GBG91370.1 - 0.16 12.8 0.7 0.61 11.0 0.7 2.1 1 0 0 1 1 1 0 ACTH-associated domain DUF3678 PF12435.8 GBG91370.1 - 0.41 10.0 2.6 5.8 6.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) PHY PF00360.20 GBG91371.1 - 6.6e-58 195.0 0.0 1.3e-57 194.1 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region PAS PF00989.25 GBG91371.1 - 1.1e-42 144.6 0.1 8.2e-22 77.3 0.1 2.7 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 GBG91371.1 - 7.7e-34 116.6 0.0 3e-33 114.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold GAF PF01590.26 GBG91371.1 - 3e-32 112.0 0.1 9.4e-32 110.4 0.1 1.9 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 GBG91371.1 - 9.5e-16 58.3 0.0 2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 GBG91371.1 - 1.9e-11 44.2 0.0 1.9e-07 31.3 0.0 2.8 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 GBG91371.1 - 4e-08 33.2 0.6 1.5e-07 31.4 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 GBG91371.1 - 6.1e-07 29.6 0.1 0.016 15.5 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS_8 PF13188.7 GBG91371.1 - 2.7e-05 24.1 0.0 0.31 11.1 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 GBG91371.1 - 0.00037 20.7 0.0 0.076 13.3 0.0 3.1 2 0 0 2 2 2 1 PAS fold Spot_14 PF07084.12 GBG91371.1 - 0.64 10.2 2.8 7.1 6.8 2.8 2.3 1 1 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 DUF3807 PF12720.7 GBG91374.1 - 0.22 11.8 16.6 0.065 13.5 13.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF2201_N PF13203.6 GBG91374.1 - 2 7.9 8.0 3.7 7.1 8.0 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.12 GBG91374.1 - 5.8 5.0 24.8 9.3 4.3 24.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG91374.1 - 8.3 5.7 15.2 14 5.0 15.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AP1AR PF15745.5 GBG91376.1 - 0.0017 18.1 16.0 0.002 17.8 16.0 1.1 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein DUF5401 PF17380.2 GBG91376.1 - 0.079 11.0 20.4 0.087 10.9 20.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SRP-alpha_N PF04086.13 GBG91376.1 - 0.14 12.0 9.3 0.17 11.8 9.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FlgH PF02107.16 GBG91376.1 - 0.23 11.0 2.1 0.54 9.9 2.1 1.6 1 1 0 1 1 1 0 Flagellar L-ring protein SmAKAP PF15127.6 GBG91376.1 - 0.36 12.1 10.7 0.14 13.4 8.3 1.5 2 0 0 2 2 1 0 Small membrane A-kinase anchor protein NPAT_C PF15712.5 GBG91376.1 - 0.46 9.1 7.4 0.52 8.9 7.4 1.1 1 0 0 1 1 1 0 NPAT C terminus CDRT4 PF15213.6 GBG91376.1 - 0.54 10.9 6.4 0.7 10.5 6.4 1.2 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein YjbH PF06082.11 GBG91376.1 - 0.98 8.2 3.4 1.1 8.0 3.4 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF1488 PF07369.11 GBG91376.1 - 1.6 8.8 5.8 0.29 11.1 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1488) RR_TM4-6 PF06459.12 GBG91376.1 - 2.5 7.9 11.2 3 7.6 11.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 GBG91376.1 - 3.1 5.8 5.7 2.9 5.9 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BT1 PF03092.16 GBG91376.1 - 6.2 4.9 5.4 7.6 4.6 5.4 1.0 1 0 0 1 1 1 0 BT1 family Presenilin PF01080.17 GBG91376.1 - 6.5 5.4 5.1 6.4 5.4 5.1 1.1 1 0 0 1 1 1 0 Presenilin DUF1682 PF07946.14 GBG91376.1 - 9.9 5.3 26.4 12 5.0 26.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PNMA PF14893.6 GBG91378.1 - 0.099 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 PNMA DDE_Tnp_4 PF13359.6 GBG91379.1 - 9.9e-29 100.0 0.0 1.4e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91379.1 - 5.4e-15 55.5 0.0 7.9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91379.1 - 9.4e-07 28.7 0.1 0.00029 20.5 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG91379.1 - 0.016 15.5 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Lipase_GDSL_2 PF13472.6 GBG91380.1 - 0.022 15.2 0.7 0.2 12.1 0.2 2.2 1 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family RXLR PF16810.5 GBG91381.1 - 0.034 14.6 0.3 0.09 13.2 0.3 1.7 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity RVT_1 PF00078.27 GBG91381.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Terminase_2 PF03592.16 GBG91383.1 - 0.00058 20.3 4.3 0.19 12.2 0.3 2.4 2 0 0 2 2 2 2 Terminase small subunit HTH_18 PF12833.7 GBG91383.1 - 0.00092 19.4 0.3 2.4 8.5 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain T4_Rnl2_C PF18043.1 GBG91383.1 - 0.01 16.0 3.8 2.5 8.3 0.2 3.0 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal MgtE_N PF03448.17 GBG91383.1 - 0.029 15.0 11.0 1.3 9.7 1.9 2.6 2 0 0 2 2 2 0 MgtE intracellular N domain EnY2 PF10163.9 GBG91383.1 - 0.55 10.6 10.0 1.6 9.2 1.9 2.5 2 0 0 2 2 2 0 Transcription factor e(y)2 YtxH PF12732.7 GBG91383.1 - 5 7.7 11.5 18 6.0 2.0 2.7 2 0 0 2 2 2 0 YtxH-like protein H_PPase PF03030.16 GBG91384.1 - 1.6e-250 833.3 36.4 1.9e-250 833.0 36.4 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF659 PF04937.15 GBG91385.1 - 7.5e-14 51.8 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91385.1 - 0.00076 19.2 0.0 0.0024 17.6 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Dimer_Tnp_hAT PF05699.14 GBG91388.1 - 0.0011 18.7 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CENP-B_dimeris PF09026.10 GBG91392.1 - 0.0062 16.9 4.9 0.0062 16.9 4.9 5.3 3 1 1 4 4 4 1 Centromere protein B dimerisation domain Presenilin PF01080.17 GBG91392.1 - 0.33 9.7 13.9 0.55 8.9 13.9 1.3 1 0 0 1 1 1 0 Presenilin DDE_Tnp_4 PF13359.6 GBG91393.1 - 8.5e-29 100.3 0.0 9.4e-27 93.6 0.0 2.6 2 1 1 3 3 3 2 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91393.1 - 3.2e-15 56.3 0.0 7.3e-15 55.1 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein SKG6 PF08693.10 GBG91396.1 - 0.016 14.6 8.3 0.52 9.8 3.9 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain NYD-SP28_assoc PF14775.6 GBG91396.1 - 0.054 13.6 2.0 6.4 7.0 0.6 2.3 1 1 1 2 2 2 0 Sperm tail C-terminal domain ZapB PF06005.12 GBG91396.1 - 0.06 13.8 0.9 0.13 12.7 0.9 1.6 1 0 0 1 1 1 0 Cell division protein ZapB SIKE PF05769.11 GBG91396.1 - 1.5 8.7 4.3 6.3 6.7 0.7 2.6 2 1 1 3 3 3 0 SIKE family ORC3_N PF07034.11 GBG91397.1 - 1.9e-41 142.3 10.1 1.4e-31 109.8 1.2 3.9 2 1 1 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 GBG91397.1 - 7.1e-27 94.2 7.8 8.6e-27 93.9 0.1 2.7 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal Spt20 PF12090.8 GBG91397.1 - 5e-05 23.0 3.5 0.00012 21.7 3.5 1.7 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 GBG91397.1 - 1.1 8.2 12.3 0.015 14.3 4.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Het-C PF07217.11 GBG91397.1 - 1.6 7.1 3.0 2.5 6.5 3.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C LMBR1 PF04791.16 GBG91398.1 - 0.0062 15.5 7.7 0.009 15.0 7.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF262 PF03235.14 GBG91398.1 - 0.2 11.8 5.9 0.43 10.7 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF262 O-antigen_lig PF13425.6 GBG91398.1 - 0.21 10.3 7.9 0.35 9.6 7.9 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF5069 PF16798.5 GBG91398.1 - 2.8 8.1 10.0 1.3 9.2 0.3 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5069) DNA_pack_N PF02500.15 GBG91398.1 - 4.1 7.1 13.7 0.087 12.6 1.7 2.3 1 1 1 2 2 2 0 Probable DNA packing protein, N-terminus FliP PF00813.20 GBG91398.1 - 8.2 6.3 8.0 21 4.9 1.8 2.3 2 0 0 2 2 2 0 FliP family TBCA PF02970.16 GBG91399.1 - 3e-27 94.8 6.3 3.7e-27 94.5 6.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF1163 PF06651.11 GBG91399.1 - 0.0035 17.4 0.1 0.0069 16.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1163) HrpB7 PF09486.10 GBG91399.1 - 0.079 13.3 5.2 4 7.8 1.6 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF3391 PF11871.8 GBG91399.1 - 0.17 12.4 3.8 0.21 12.1 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Ku_C PF03730.14 GBG91399.1 - 0.48 11.2 6.5 12 6.6 3.2 2.1 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm CC2-LZ PF16516.5 GBG91399.1 - 0.57 10.6 7.9 0.39 11.1 4.1 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 GBG91399.1 - 0.81 8.5 8.6 1.6 7.5 8.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Ndufs5 PF10200.9 GBG91400.1 - 5.2e-05 23.4 1.9 0.00015 22.0 1.9 1.6 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.17 GBG91400.1 - 0.013 15.7 3.4 0.013 15.7 3.4 1.9 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 GBG91400.1 - 0.054 13.8 3.5 0.077 13.3 3.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.8 GBG91400.1 - 0.47 10.9 6.5 18 5.7 6.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) rve PF00665.26 GBG91402.1 - 4.8e-12 46.1 0.1 2e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG91402.1 - 7.2e-09 35.4 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SPX PF03105.19 GBG91403.1 - 5.2e-28 99.0 13.8 5.3e-10 39.8 0.0 3.7 2 2 2 4 4 4 3 SPX domain adh_short PF00106.25 GBG91404.1 - 5.3e-39 133.7 2.6 4.2e-37 127.5 2.6 3.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GBG91404.1 - 1.6e-28 99.9 4.1 3.3e-25 89.0 4.1 3.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG91404.1 - 8.6e-07 29.0 1.1 1.6e-06 28.2 1.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GBG91404.1 - 0.0083 15.6 0.1 0.027 13.9 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 GBG91404.1 - 0.047 13.6 0.4 0.073 12.9 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GBG91404.1 - 0.17 11.3 0.2 0.28 10.5 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SPRY PF00622.28 GBG91406.1 - 1.7e-05 24.9 0.0 0.0003 20.9 0.0 2.3 2 0 0 2 2 2 1 SPRY domain Plasmodium_Vir PF05795.11 GBG91406.1 - 0.49 9.8 2.3 0.7 9.2 2.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CC190 PF15768.5 GBG91406.1 - 0.57 10.2 5.6 0.85 9.6 5.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Sporozoite_P67 PF05642.11 GBG91407.1 - 0.0019 16.4 8.8 0.0026 15.9 8.8 1.3 1 1 0 1 1 1 1 Sporozoite P67 surface antigen BUD22 PF09073.10 GBG91408.1 - 0.1 11.9 12.6 0.18 11.1 12.6 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG91408.1 - 1.1 7.5 10.0 1.6 6.9 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GBG91408.1 - 2.2 8.0 11.1 3.9 7.1 11.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4360 PF14273.6 GBG91410.1 - 7.4e-27 94.4 0.6 8.9e-27 94.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG91413.1 - 9.4e-27 93.0 0.0 1.8e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91413.1 - 3.8e-24 85.4 0.1 6.8e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91413.1 - 4.8e-23 81.4 0.0 1.1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91415.1 - 4.7e-16 59.0 0.0 1.2e-15 57.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG91415.1 - 4.1e-08 33.1 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91415.1 - 5.4e-08 33.4 0.0 1.9e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91415.1 - 7.7e-06 26.4 0.0 4.2e-05 24.0 0.0 2.3 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG91415.1 - 0.00042 20.5 0.7 0.0016 18.6 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 GBG91415.1 - 0.0024 17.7 0.0 0.0072 16.2 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Retrotrans_gag PF03732.17 GBG91415.1 - 0.0025 18.0 0.3 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG91415.1 - 0.0046 16.7 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease WTX PF09422.10 GBG91415.1 - 0.18 10.9 7.7 0.019 14.1 2.2 1.9 2 0 0 2 2 2 0 WTX protein Fib_alpha PF08702.10 GBG91415.1 - 2.3 8.4 4.7 6 7.0 0.1 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family RT_RNaseH_2 PF17919.1 GBG91416.1 - 6e-30 103.2 0.0 1.5e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91416.1 - 7e-18 64.9 0.0 1.3e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91416.1 - 7.4e-18 64.8 0.0 2e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG91416.1 - 2.4e-08 34.2 0.0 5.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain SpecificRecomb PF10136.9 GBG91416.1 - 1.4 7.1 4.9 2.5 6.3 4.9 1.3 1 0 0 1 1 1 0 Site-specific recombinase PolyA_pol PF01743.20 GBG91416.1 - 4.8 7.6 5.7 1.3 9.5 1.5 2.1 1 1 1 2 2 2 0 Poly A polymerase head domain RT_RNaseH_2 PF17919.1 GBG91417.1 - 1.4e-23 82.8 0.0 2e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91417.1 - 7.9e-13 48.6 0.0 1.9e-12 47.4 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_lysozyme PF00959.19 GBG91418.1 - 0.12 12.9 0.0 0.42 11.1 0.0 1.9 1 0 0 1 1 1 0 Phage lysozyme RVT_1 PF00078.27 GBG91420.1 - 6.7e-31 107.5 0.1 9.8e-31 107.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91420.1 - 1e-25 89.6 0.0 2.3e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91420.1 - 2.2e-24 85.8 0.0 4.6e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91420.1 - 5.6e-19 68.0 0.3 1.6e-18 66.5 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain ADK PF00406.22 GBG91420.1 - 0.00013 22.1 0.0 0.0024 18.0 0.0 2.4 2 0 0 2 2 2 1 Adenylate kinase rve PF00665.26 GBG91420.1 - 0.058 13.6 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 GBG91420.1 - 0.1 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Longin PF13774.6 GBG91420.1 - 0.27 11.3 1.9 1.8 8.7 0.2 2.7 2 1 0 2 2 2 0 Regulated-SNARE-like domain HAGH_C PF16123.5 GBG91421.1 - 0.027 15.0 0.1 0.22 12.1 0.1 2.6 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Telomere_reg-2 PF10193.9 GBG91422.1 - 2.2e-16 60.3 0.0 7.1e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein Dicty_REP PF05086.12 GBG91422.1 - 3.7 5.4 16.5 7.1 4.5 16.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Plavaka PF18759.1 GBG91424.1 - 4.4e-24 85.3 0.3 8.6e-24 84.4 0.3 1.4 1 0 0 1 1 1 1 Plavaka transposase Histone PF00125.24 GBG91424.1 - 2e-19 70.3 0.0 2e-19 70.3 0.0 3.4 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 FancD2 PF14631.6 GBG91424.1 - 0.25 8.7 0.6 0.47 7.8 0.6 1.3 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF659 PF04937.15 GBG91425.1 - 1.6e-23 83.3 0.0 3.1e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVP_2 PF08284.11 GBG91425.1 - 0.04 13.7 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG91425.1 - 0.096 12.4 0.3 0.26 11.0 0.3 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like FYVE PF01363.21 GBG91425.1 - 9.2 6.5 7.2 0.59 10.3 0.8 2.2 2 0 0 2 2 2 0 FYVE zinc finger DUF2719 PF10891.8 GBG91428.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) zf-CCHC PF00098.23 GBG91429.1 - 7.9e-06 25.7 4.3 1.4e-05 24.9 4.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG91429.1 - 0.016 15.0 4.9 0.026 14.3 4.9 1.3 1 0 0 1 1 1 0 Zinc knuckle VSG_B PF13206.6 GBG91429.1 - 0.5 9.6 8.8 0.76 9.0 8.8 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain BUD22 PF09073.10 GBG91429.1 - 1.4 8.2 24.6 0.023 14.0 16.8 1.7 2 0 0 2 2 2 0 BUD22 Pkinase_Tyr PF07714.17 GBG91430.1 - 1.4e-50 172.0 0.0 1.7e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG91430.1 - 1e-49 169.3 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG91430.1 - 0.0022 18.0 0.3 1.7 8.5 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG91430.1 - 0.011 14.6 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Rab3-GTPase_cat PF13890.6 GBG91431.1 - 1.1e-44 152.0 0.2 1.1e-43 148.7 0.0 2.7 3 1 0 3 3 3 1 Rab3 GTPase-activating protein catalytic subunit BSD PF03909.17 GBG91431.1 - 4.5e-10 39.4 0.0 9.3e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 BSD domain Rab3-GTPase_cat PF13890.6 GBG91432.1 - 3.5e-48 163.3 0.1 3.7e-47 160.0 0.0 2.7 3 1 0 3 3 3 1 Rab3 GTPase-activating protein catalytic subunit BSD PF03909.17 GBG91432.1 - 4.4e-10 39.4 0.0 9.2e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 BSD domain HisKA PF00512.25 GBG91434.1 - 0.0061 16.6 0.7 0.015 15.3 0.7 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain RVT_1 PF00078.27 GBG91435.1 - 3.5e-29 101.9 0.1 5.3e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91435.1 - 6e-17 61.5 0.3 1.6e-16 60.1 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG91435.1 - 5.7e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91435.1 - 0.0047 17.1 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF2862 PF11061.8 GBG91435.1 - 0.023 14.5 0.1 0.054 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) TOBE_2 PF08402.10 GBG91435.1 - 0.038 14.1 0.3 2.4 8.4 0.0 2.9 3 0 0 3 3 3 0 TOBE domain Chromo PF00385.24 GBG91435.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain HATPase_c PF02518.26 GBG91436.1 - 1.4e-11 44.9 0.0 3.7e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GBG91436.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Exo_endo_phos PF03372.23 GBG91437.1 - 0.002 17.7 0.1 0.0041 16.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 GBG91438.1 - 1.6e-38 132.5 0.0 2.6e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91438.1 - 9e-13 48.1 0.4 2.5e-12 46.7 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91438.1 - 1.2e-12 48.0 0.0 2.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Jnk-SapK_ap_N PF09744.9 GBG91438.1 - 0.0031 17.8 4.8 0.0082 16.4 4.8 1.6 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Csm1_N PF18504.1 GBG91438.1 - 0.9 9.9 2.9 2.9 8.3 2.9 1.9 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF3347 PF11827.8 GBG91438.1 - 2.4 8.3 4.2 5.2 7.2 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Atg14 PF10186.9 GBG91438.1 - 4.1 6.4 6.3 7.1 5.6 6.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 gag-asp_proteas PF13975.6 GBG91439.1 - 1.2e-05 25.7 0.3 0.00041 20.9 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91439.1 - 0.0016 19.0 0.1 0.0093 16.6 0.0 2.3 3 0 0 3 3 3 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG91440.1 - 2.6e-28 98.0 0.0 4.8e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91440.1 - 1e-23 83.6 0.0 2.1e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91440.1 - 5.6e-16 58.7 0.0 9.7e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG91440.1 - 0.0001 22.2 4.5 0.00019 21.3 4.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG91440.1 - 0.0024 17.6 6.4 0.0057 16.4 6.4 1.7 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.9 GBG91441.1 - 0.0062 16.2 31.3 0.0085 15.7 31.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Exonuc_VII_L PF02601.15 GBG91441.1 - 0.3 10.6 11.2 0.4 10.2 11.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SRP-alpha_N PF04086.13 GBG91441.1 - 1.8 8.4 23.0 2.2 8.1 23.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CRT10 PF08728.10 GBG91441.1 - 4.3 5.4 13.3 4.9 5.2 13.3 1.0 1 0 0 1 1 1 0 CRT10 CytB6-F_Fe-S PF08802.10 GBG91442.1 - 3.5e-14 52.5 0.9 1.2e-13 50.8 0.9 2.0 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit Rieske PF00355.26 GBG91442.1 - 6.9e-13 48.4 0.1 1.1e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain WHAMM-JMY_N PF15920.5 GBG91442.1 - 0.018 14.9 0.4 0.029 14.2 0.4 1.3 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated RT_RNaseH_2 PF17919.1 GBG91443.1 - 1.1e-32 112.0 0.0 2.4e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91443.1 - 6.1e-30 104.4 0.1 9.6e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91443.1 - 4.1e-29 100.9 0.0 1.1e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ChpA-C PF03777.13 GBG91443.1 - 5.6 6.9 7.6 0.22 11.4 1.1 2.0 2 0 0 2 2 2 0 ChpA-C HrpB7 PF09486.10 GBG91444.1 - 0.04 14.3 0.0 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) RE_XamI PF09572.10 GBG91444.1 - 0.065 12.9 0.0 6.3 6.4 0.0 2.4 2 1 0 2 2 2 0 XamI restriction endonuclease PapC_N PF13954.6 GBG91444.1 - 0.15 12.0 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 PapC N-terminal domain Jnk-SapK_ap_N PF09744.9 GBG91445.1 - 0.011 16.0 1.7 0.011 16.0 1.7 3.0 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF5476 PF17570.2 GBG91445.1 - 0.12 12.8 1.4 0.63 10.5 1.4 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5476) gag-asp_proteas PF13975.6 GBG91445.1 - 0.18 12.4 0.8 1 10.0 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG91447.1 - 8.9e-29 100.6 0.0 1.6e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91447.1 - 2.5e-28 98.0 0.2 4.4e-26 90.8 0.0 3.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91447.1 - 5.9e-25 87.6 0.1 3.7e-24 85.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG91447.1 - 0.0013 19.0 2.8 0.0052 17.0 0.3 3.3 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4292 PF14125.6 GBG91447.1 - 0.064 12.9 0.1 7.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4292) Acetyltransf_6 PF13480.7 GBG91448.1 - 8 6.6 7.5 0.79 9.9 1.6 2.2 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain RVT_1 PF00078.27 GBG91449.1 - 4.2e-07 29.7 0.0 5.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG91451.1 - 0.12 10.6 12.9 0.17 10.0 12.9 1.3 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 GBG91451.1 - 5.2 6.0 8.6 8.9 5.2 8.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DIM1 PF02966.16 GBG91452.1 - 2.9e-30 104.8 0.5 3.4e-30 104.5 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 GBG91452.1 - 0.0011 18.9 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Ribosomal_L13e PF01294.18 GBG91453.1 - 3.9e-77 258.2 1.2 4.7e-77 257.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_60s PF00428.19 GBG91454.1 - 0.052 14.1 0.9 0.052 14.1 0.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2407_C PF13373.6 GBG91454.1 - 0.12 12.6 1.6 0.32 11.2 1.6 1.8 1 0 0 1 1 1 0 DUF2407 C-terminal domain CCDC53 PF10152.9 GBG91454.1 - 0.76 10.2 17.1 0.2 12.1 3.2 2.3 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Macoilin PF09726.9 GBG91454.1 - 1.3 7.5 22.0 1.7 7.1 22.0 1.1 1 0 0 1 1 1 0 Macoilin family Leucyl-specific PF14795.6 GBG91455.1 - 0.36 10.9 7.1 6.9 6.8 0.7 3.7 3 0 0 3 3 3 0 Leucine-tRNA synthetase-specific domain Golgin_A5 PF09787.9 GBG91456.1 - 0.0081 15.7 4.2 0.015 14.8 4.2 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 ADIP PF11559.8 GBG91456.1 - 0.15 12.1 5.5 0.27 11.3 5.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DMPK_coil PF08826.10 GBG91456.1 - 0.32 11.1 11.3 0.12 12.5 7.9 2.1 2 1 0 2 2 2 0 DMPK coiled coil domain like NINJA_B PF16136.5 GBG91456.1 - 1.6 9.1 7.8 4.1 7.8 7.8 1.7 1 0 0 1 1 1 0 Putative nuclear localisation signal Med9 PF07544.13 GBG91457.1 - 4.5 7.4 20.2 0.59 10.3 0.4 4.1 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HSP70 PF00012.20 GBG91458.1 - 1.2e-121 406.8 0.0 1.5e-121 406.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG91458.1 - 1.2e-07 30.8 0.5 2.5e-07 29.8 0.5 1.5 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 GBG91458.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain AF0941-like PF14591.6 GBG91458.1 - 0.11 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 AF0941-like RVT_1 PF00078.27 GBG91459.1 - 2.3e-28 99.2 0.2 5e-28 98.1 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91459.1 - 0.00055 20.5 0.0 0.0024 18.5 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease WTX PF09422.10 GBG91459.1 - 0.0011 18.1 0.7 0.0022 17.2 0.7 1.4 1 0 0 1 1 1 1 WTX protein gag-asp_proteas PF13975.6 GBG91459.1 - 0.0051 17.3 0.3 0.024 15.2 0.0 2.3 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG91459.1 - 0.017 15.4 0.1 0.28 11.5 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein IL28A PF15177.6 GBG91459.1 - 0.1 12.5 3.2 0.47 10.3 3.3 2.0 2 0 0 2 2 2 0 Interleukin-28A TolA_bind_tri PF16331.5 GBG91459.1 - 1 9.5 5.8 1.2 9.3 3.9 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation HSP70 PF00012.20 GBG91460.1 - 4.9e-99 332.2 0.0 3.1e-72 243.6 0.1 2.2 2 0 0 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG91460.1 - 1.2e-11 44.4 0.0 8.6e-07 28.6 0.0 4.4 3 1 1 4 4 4 2 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG91460.1 - 2.5e-06 26.6 0.2 0.0037 16.1 0.7 3.0 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG91460.1 - 0.016 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF2663 PF10864.8 GBG91460.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Mitofilin PF09731.9 GBG91463.1 - 0.74 8.6 36.9 1.1 8.0 36.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Presenilin PF01080.17 GBG91463.1 - 1.1 8.0 31.7 1.5 7.5 31.7 1.1 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 GBG91463.1 - 1.4 8.3 61.0 2.3 7.5 61.0 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG91463.1 - 2.8 6.1 58.8 4.3 5.4 58.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG91463.1 - 3.4 5.9 42.9 7 4.8 42.9 1.4 1 0 0 1 1 1 0 CDC45-like protein gag-asp_proteas PF13975.6 GBG91464.1 - 6e-07 29.9 0.1 1.1e-06 29.1 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91464.1 - 2.6e-06 28.0 0.0 4.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG91464.1 - 0.00015 21.5 0.4 0.00032 20.5 0.4 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG91464.1 - 0.0073 16.6 0.1 0.038 14.3 0.1 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease PTPRCAP PF15713.5 GBG91464.1 - 0.12 12.7 7.5 0.21 11.9 7.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 GBG91464.1 - 2.3 7.8 5.6 4.2 7.0 5.6 1.4 1 0 0 1 1 1 0 FAM176 family BNIP3 PF06553.12 GBG91464.1 - 5.2 6.7 5.5 8.2 6.0 5.5 1.2 1 0 0 1 1 1 0 BNIP3 CAC1F_C PF16885.5 GBG91465.1 - 7.1 6.2 13.6 9.5 5.8 13.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF4778 PF16008.5 GBG91465.1 - 9.1 6.2 13.1 12 5.8 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) RVT_1 PF00078.27 GBG91466.1 - 3.1e-30 105.4 0.1 5.1e-30 104.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91466.1 - 1.7e-15 56.9 0.0 6.8e-15 54.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91466.1 - 0.00026 21.2 0.0 0.0008 19.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3863 PF12979.7 GBG91466.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) BLOC1S3 PF15753.5 GBG91467.1 - 0.4 10.8 0.1 0.4 10.8 0.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 FAM60A PF15396.6 GBG91467.1 - 0.77 9.7 5.2 13 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Presenilin PF01080.17 GBG91467.1 - 1.3 7.7 5.6 2.2 6.9 5.6 1.2 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG91468.1 - 5.1e-53 177.3 0.0 4.7e-31 106.8 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91468.1 - 3.1e-42 143.1 0.2 1.3e-20 73.6 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91468.1 - 2.8e-33 115.3 0.1 8.9e-18 64.6 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1664 PF07889.12 GBG91468.1 - 0.0025 17.8 1.3 0.0079 16.2 1.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) rve PF00665.26 GBG91468.1 - 0.011 15.9 0.1 0.043 14.0 0.1 2.1 1 0 0 1 1 1 0 Integrase core domain Spc29 PF17082.5 GBG91468.1 - 0.018 14.9 0.1 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 ATG16 PF08614.11 GBG91468.1 - 0.19 11.9 17.2 0.59 10.3 17.2 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 GBG91468.1 - 0.82 9.8 8.6 0.15 12.2 2.7 2.8 3 0 0 3 3 3 0 TolA binding protein trimerisation CorA PF01544.18 GBG91468.1 - 4 6.7 5.5 24 4.1 0.1 2.8 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Asp_protease PF09668.10 GBG91469.1 - 1.5e-08 34.4 0.0 3.6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91469.1 - 1.9e-08 34.8 0.0 6.8e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91469.1 - 1.5e-06 28.8 0.0 3.8e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease MmoB_DmpM PF02406.17 GBG91469.1 - 0.049 13.9 0.2 0.16 12.2 0.2 1.8 1 0 0 1 1 1 0 MmoB/DmpM family RVP PF00077.20 GBG91469.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DDHD PF02862.17 GBG91469.1 - 3.6 7.7 7.0 1.7 8.7 4.4 1.7 1 1 0 1 1 1 0 DDHD domain RVT_1 PF00078.27 GBG91470.1 - 1.9e-34 119.1 0.0 3.5e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91470.1 - 7.8e-16 57.9 0.0 2.1e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91470.1 - 1e-06 28.9 0.0 2.6e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91471.1 - 4.2e-26 91.8 0.1 8.3e-26 90.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91471.1 - 2.4e-23 82.1 0.0 5.8e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91471.1 - 3e-21 75.7 0.0 1.1e-20 73.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91471.1 - 1.4e-15 57.1 0.7 4.5e-15 55.5 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 GBG91471.1 - 4.1e-07 30.5 0.0 1.2e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91471.1 - 6.4e-07 29.9 0.0 2.2e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG91471.1 - 2.5e-06 27.3 0.0 5.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG91471.1 - 0.004 17.3 0.1 0.0096 16.1 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Herpes_BLRF2 PF05812.12 GBG91471.1 - 0.051 13.7 0.6 13 6.0 0.2 3.2 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein TSC22 PF01166.18 GBG91471.1 - 0.11 12.8 1.4 5.1 7.5 0.1 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family HALZ PF02183.18 GBG91471.1 - 0.88 9.8 3.3 0.41 10.9 0.2 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Retrotrans_gag PF03732.17 GBG91471.1 - 1.1 9.6 5.8 13 6.2 0.1 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein DUF4187 PF13821.6 GBG91472.1 - 0.0015 18.3 0.9 0.0015 18.3 0.9 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG91472.1 - 0.0029 17.8 0.1 0.0029 17.8 0.1 3.1 2 1 1 3 3 3 1 Retrotransposon gag protein HMMR_N PF15905.5 GBG91472.1 - 1.2 8.5 6.5 0.43 10.0 2.6 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FUSC PF04632.12 GBG91472.1 - 2.4 6.6 7.3 2.9 6.3 5.5 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Presenilin PF01080.17 GBG91473.1 - 0.16 10.7 3.6 0.23 10.2 3.6 1.1 1 0 0 1 1 1 0 Presenilin N6_N4_Mtase PF01555.18 GBG91474.1 - 6.2e-06 26.1 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 DNA methylase CobT PF06213.12 GBG91474.1 - 1.8 7.9 10.3 3.9 6.8 10.3 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 GBG91474.1 - 2.2 7.9 5.6 6 6.5 5.6 1.7 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 GBG91474.1 - 3.2 8.2 10.7 15 6.1 10.7 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 GBG91474.1 - 7.1 4.6 13.8 11 4.0 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG91474.1 - 8.5 4.4 13.0 13 3.9 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 GBG91474.1 - 9.2 5.3 16.3 15 4.6 16.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MRP-S35 PF10246.9 GBG91476.1 - 0.039 13.9 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 RVT_1 PF00078.27 GBG91477.1 - 8.3e-35 120.3 0.0 1.4e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91477.1 - 9.1e-21 73.8 0.0 2.3e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91477.1 - 2.9e-09 37.2 0.0 7.1e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4790 PF16037.5 GBG91477.1 - 0.12 12.9 1.4 0.31 11.5 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4790) Phage_lysozyme PF00959.19 GBG91477.1 - 0.18 12.2 0.2 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Phage lysozyme DDE_Tnp_4 PF13359.6 GBG91478.1 - 2.3e-06 27.4 0.6 8.2e-06 25.6 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 GBG91478.1 - 0.027 14.8 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain Plant_tran PF04827.14 GBG91478.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG91479.1 - 1.4e-07 31.8 0.6 3.6e-07 30.5 0.5 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91479.1 - 0.0023 18.2 0.1 0.0059 16.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 GBG91479.1 - 0.0024 18.0 0.0 0.21 11.8 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Sporozoite_P67 PF05642.11 GBG91480.1 - 0.071 11.2 2.4 0.085 10.9 2.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HSP70 PF00012.20 GBG91483.1 - 4.2e-167 557.0 0.0 5.1e-167 556.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG91483.1 - 2.9e-10 39.5 3.1 7.8e-08 31.5 1.6 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG91483.1 - 7e-05 22.6 0.4 0.0002 21.1 0.4 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG91483.1 - 0.081 13.4 0.8 22 5.5 0.0 2.9 2 1 0 2 2 2 0 Cell division protein FtsA GNAT_acetyltr_2 PF13718.6 GBG91483.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 gag-asp_proteas PF13975.6 GBG91484.1 - 3.4e-07 30.7 0.1 8.1e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91484.1 - 8e-05 23.2 0.1 0.00018 22.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG91484.1 - 0.0012 18.6 0.1 0.0021 17.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG91484.1 - 0.0081 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG91484.1 - 0.072 12.8 0.7 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Herpes_DNAp_acc PF04929.12 GBG91485.1 - 3.4 6.5 4.3 4.9 6.0 4.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MAP17 PF15807.5 GBG91486.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF659 PF04937.15 GBG91487.1 - 1.5e-34 119.0 0.3 2.4e-34 118.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RNA_pol_3_Rpc31 PF11705.8 GBG91487.1 - 0.19 12.0 8.6 0.041 14.1 4.5 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Trypan_PARP PF05887.11 GBG91487.1 - 5.5 7.0 8.4 11 6.0 1.4 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Bacteriocin_IIc PF10439.9 GBG91488.1 - 0.56 10.4 8.4 0.76 9.9 7.5 1.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Tetraspanin PF00335.20 GBG91489.1 - 2.4e-05 24.2 7.7 8.6e-05 22.4 7.7 1.7 1 1 0 1 1 1 1 Tetraspanin family DUF2339 PF10101.9 GBG91489.1 - 0.096 11.3 7.0 0.14 10.7 7.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) ABC2_membrane_3 PF12698.7 GBG91489.1 - 0.82 8.7 9.4 1.2 8.2 9.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Pox_A14 PF05767.12 GBG91493.1 - 0.057 13.6 0.1 0.057 13.6 0.1 2.9 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 SirB PF04247.12 GBG91493.1 - 0.19 11.8 5.4 0.19 11.8 2.1 2.1 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB ABC2_membrane_3 PF12698.7 GBG91493.1 - 0.31 10.1 3.0 0.59 9.2 3.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1218 PF06749.12 GBG91493.1 - 1.1 9.8 12.1 9.1 6.9 0.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) YiaAB PF05360.14 GBG91493.1 - 1.6 9.0 10.3 4.1 7.7 0.0 3.2 2 1 1 3 3 3 0 yiaA/B two helix domain NPV_P10 PF05531.12 GBG91494.1 - 0.029 14.8 0.5 0.52 10.8 0.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4559 PF15112.6 GBG91494.1 - 0.96 9.1 9.2 1.9 8.1 6.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) BLOC1_2 PF10046.9 GBG91494.1 - 2.8 8.3 7.8 0.2 12.0 1.4 2.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LRR_8 PF13855.6 GBG91496.1 - 4e-09 36.1 0.8 5.7e-09 35.6 0.8 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GBG91496.1 - 0.00011 22.4 3.5 0.00051 20.4 1.0 2.2 1 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GBG91496.1 - 0.0021 18.4 0.8 0.8 10.5 0.2 3.1 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_9 PF14580.6 GBG91496.1 - 0.036 13.6 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat LRR_5 PF13306.6 GBG91496.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) RT_RNaseH_2 PF17919.1 GBG91497.1 - 7.5e-32 109.3 0.0 1.5e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91497.1 - 4.9e-30 104.7 0.0 8.4e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91497.1 - 1.9e-28 98.8 0.0 3.7e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91497.1 - 8.2e-16 57.9 0.0 2e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91497.1 - 2.5e-15 56.7 0.1 9.9e-15 54.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DUF5095 PF17016.5 GBG91497.1 - 0.1 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Cobl PF09469.10 GBG91497.1 - 0.14 12.4 0.1 0.54 10.6 0.0 1.9 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain SET PF00856.28 GBG91499.1 - 5.2e-17 62.7 0.1 5.2e-17 62.7 0.1 2.9 3 0 0 3 3 3 1 SET domain AWS PF17907.1 GBG91499.1 - 1.3e-11 44.4 12.0 5.1e-11 42.4 12.0 2.1 1 0 0 1 1 1 1 AWS domain Presenilin PF01080.17 GBG91500.1 - 1.3 7.7 3.8 1.7 7.3 3.8 1.1 1 0 0 1 1 1 0 Presenilin Complex1_LYR PF05347.15 GBG91501.1 - 3.4e-05 23.8 0.0 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GBG91501.1 - 0.0092 16.7 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like DDE_Tnp_4 PF13359.6 GBG91502.1 - 3.3e-27 95.1 0.0 1.8e-26 92.7 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91502.1 - 1.6e-13 50.7 0.0 3.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91502.1 - 0.00019 21.2 0.6 1.9 8.1 0.0 3.3 3 0 0 3 3 3 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG91502.1 - 0.025 14.9 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain Nop14 PF04147.12 GBG91503.1 - 5.6 5.0 4.3 6.9 4.7 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family FAM76 PF16046.5 GBG91505.1 - 0.39 10.0 8.3 0.81 9.0 8.3 1.4 1 0 0 1 1 1 0 FAM76 protein PRTP PF01366.18 GBG91505.1 - 3.9 5.4 6.9 7.6 4.4 6.9 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein zf-C2H2 PF00096.26 GBG91506.1 - 4.3e-21 74.1 29.7 0.00012 22.3 0.3 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GBG91506.1 - 1.2e-12 47.5 29.6 0.012 16.4 3.2 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GBG91506.1 - 1.6e-09 37.8 11.7 2.2e-06 27.8 2.6 6.6 7 0 0 7 7 7 3 Zinc-finger double domain zf-Di19 PF05605.12 GBG91506.1 - 0.025 14.9 21.6 0.77 10.1 0.1 4.3 2 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 GBG91506.1 - 0.27 11.3 22.4 4 7.6 2.5 4.6 2 2 3 5 5 5 0 Aberrant zinc-finger CCAP PF11105.8 GBG91506.1 - 0.38 10.7 2.7 19 5.2 0.0 3.1 2 1 1 3 3 3 0 Arthropod cardioacceleratory peptide 2a DUF4729 PF15866.5 GBG91506.1 - 0.51 9.6 0.0 0.51 9.6 0.0 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4729) FOXP-CC PF16159.5 GBG91506.1 - 1.7 9.4 15.3 6.3 7.5 0.1 5.1 3 1 3 6 6 6 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 GBG91506.1 - 3.6 8.0 11.2 7.4 7.0 0.9 4.9 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-CGNR PF11706.8 GBG91506.1 - 5.9 6.8 7.3 3.7 7.5 0.1 3.5 4 0 0 4 4 4 0 CGNR zinc finger zf-C2H2_11 PF16622.5 GBG91506.1 - 6.2 6.7 9.8 37 4.2 0.0 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 GBG91506.1 - 6.6 7.1 10.3 3 8.2 1.4 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon Mpp10 PF04006.12 GBG91507.1 - 9.4e-05 21.1 11.5 9.4e-05 21.1 11.5 1.1 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.14 GBG91507.1 - 0.00024 19.6 14.0 0.00025 19.5 14.0 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG91507.1 - 0.0016 16.8 26.2 0.0018 16.6 26.2 1.1 1 0 0 1 1 1 1 Nop14-like family DNA_pol_phi PF04931.13 GBG91507.1 - 0.0084 14.3 42.3 0.012 13.8 42.3 1.2 1 0 0 1 1 1 1 DNA polymerase phi RRN3 PF05327.11 GBG91507.1 - 0.02 13.5 23.5 0.021 13.4 23.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.12 GBG91507.1 - 0.58 9.1 3.0 0.71 8.8 3.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 GBG91507.1 - 0.91 8.2 10.2 1.1 7.9 10.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 GBG91508.1 - 0.0023 17.5 25.0 0.0027 17.2 25.0 1.1 1 0 0 1 1 1 1 SDA1 Na_trans_assoc PF06512.13 GBG91508.1 - 0.0023 18.3 11.8 0.0025 18.2 11.8 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated BUD22 PF09073.10 GBG91508.1 - 0.0065 15.9 21.0 0.0084 15.5 21.0 1.1 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 GBG91508.1 - 0.0094 14.3 17.6 0.011 14.1 17.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG91508.1 - 0.015 13.5 28.1 0.019 13.2 28.1 1.1 1 0 0 1 1 1 0 Nop14-like family SpoIIP PF07454.11 GBG91508.1 - 0.016 14.7 5.9 0.02 14.3 5.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 GBG91508.1 - 0.019 14.2 2.0 0.017 14.3 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 GBG91508.1 - 0.14 10.6 30.4 0.19 10.2 30.4 1.1 1 0 0 1 1 1 0 Mpp10 protein Presenilin PF01080.17 GBG91508.1 - 0.15 10.8 7.3 0.21 10.3 7.3 1.1 1 0 0 1 1 1 0 Presenilin SpoIIIAH PF12685.7 GBG91508.1 - 0.38 10.6 12.3 0.49 10.2 12.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 GBG91508.1 - 1.1 9.7 10.3 2.4 8.6 10.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 GBG91508.1 - 1.3 7.0 36.6 1.7 6.7 36.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2151 PF10221.9 GBG91508.1 - 1.4 7.4 5.0 1.6 7.2 5.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Hid1 PF12722.7 GBG91508.1 - 2.4 6.2 5.1 2.9 5.9 5.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 GBG91508.1 - 3.1 7.5 20.6 4.6 7.0 20.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 GBG91508.1 - 8.1 4.2 12.2 9.8 3.9 12.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RVT_1 PF00078.27 GBG91509.1 - 6.9e-30 104.2 0.1 1.5e-29 103.1 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91509.1 - 3.1e-17 62.5 0.0 2.8e-16 59.4 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91509.1 - 3.9e-09 36.8 0.0 1.2e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4392 PF14336.6 GBG91509.1 - 0.045 13.2 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Herpes_BLRF2 PF05812.12 GBG91510.1 - 0.012 15.8 0.5 0.012 15.8 0.5 2.0 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein FAM76 PF16046.5 GBG91510.1 - 3.8 6.8 5.9 12 5.1 5.9 1.8 1 1 0 1 1 1 0 FAM76 protein Troponin PF00992.20 GBG91510.1 - 5.1 7.4 9.6 9 6.6 7.8 2.1 2 0 0 2 2 2 0 Troponin RVT_1 PF00078.27 GBG91511.1 - 4.8e-29 101.4 0.1 7.9e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91511.1 - 2.6e-08 34.4 0.0 5.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease TPH PF13868.6 GBG91511.1 - 4.1e-08 32.1 78.4 5.7e-08 31.7 78.4 1.1 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain gag-asp_proteas PF13975.6 GBG91511.1 - 1.7e-07 31.7 0.0 3.5e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG91511.1 - 3.9e-06 26.7 0.0 9.6e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG91511.1 - 2.3e-05 24.2 0.0 4.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Phage_RpbA PF10789.9 GBG91511.1 - 1.8 8.7 16.2 0.081 13.0 5.7 3.1 2 1 1 3 3 3 0 Phage RNA polymerase binding, RpbA SNN_linker PF09050.10 GBG91513.1 - 0.00033 20.4 7.8 0.8 9.5 0.1 3.5 3 0 0 3 3 3 3 Stannin unstructured linker zf-CCHC PF00098.23 GBG91514.1 - 1e-05 25.3 2.1 2.1e-05 24.4 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG91514.1 - 0.026 14.2 1.5 0.058 13.1 1.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF572 PF04502.13 GBG91514.1 - 0.041 13.5 21.7 0.074 12.7 21.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2894 PF11445.8 GBG91514.1 - 2 8.9 9.9 5.7 7.4 9.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) CemA PF03040.14 GBG91514.1 - 3.9 7.3 4.0 7.1 6.5 4.0 1.4 1 0 0 1 1 1 0 CemA family Caldesmon PF02029.15 GBG91514.1 - 4.3 6.0 37.3 0.016 14.0 18.0 2.0 1 1 1 2 2 2 0 Caldesmon Auxin_inducible PF02519.14 GBG91515.1 - 5.9e-11 42.4 0.0 8.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Auxin responsive protein DUF659 PF04937.15 GBG91516.1 - 5.4e-14 52.3 0.0 8.5e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) AAA_lid_7 PF17867.1 GBG91516.1 - 0.093 12.9 1.5 0.2 11.9 1.5 1.5 1 0 0 1 1 1 0 Midasin AAA lid domain CDC45 PF02724.14 GBG91516.1 - 8.7 4.5 5.5 14 3.8 5.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Beta_helix PF13229.6 GBG91517.1 - 0.0015 18.4 4.4 0.01 15.7 3.9 2.1 1 1 1 2 2 2 2 Right handed beta helix region Beta_helix PF13229.6 GBG91518.1 - 0.0094 15.8 3.2 0.014 15.2 3.2 1.3 1 0 0 1 1 1 1 Right handed beta helix region DUF4957 PF16318.5 GBG91518.1 - 0.084 12.8 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4957) RT_RNaseH PF17917.1 GBG91519.1 - 1.9e-23 82.8 0.0 5.8e-23 81.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91519.1 - 5.2e-21 74.6 0.0 1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91519.1 - 2.6e-20 72.3 1.1 5.1e-20 71.3 1.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91519.1 - 1.6e-15 57.3 0.0 5.8e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG91519.1 - 0.0062 16.7 0.3 0.013 15.7 0.3 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DDE_Tnp_4 PF13359.6 GBG91520.1 - 4e-14 52.6 0.0 6.5e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91520.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Beta_helix PF13229.6 GBG91521.1 - 0.00012 21.9 0.2 0.00021 21.2 0.2 1.5 1 0 0 1 1 1 1 Right handed beta helix region ArnB_C PF18677.1 GBG91522.1 - 0.047 13.8 0.1 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain RVT_1 PF00078.27 GBG91523.1 - 3.8e-37 128.0 0.0 5.7e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4957 PF16318.5 GBG91524.1 - 0.036 14.0 0.3 0.081 12.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4957) DUF5123 PF17161.4 GBG91524.1 - 0.79 10.8 4.3 1.4 10.0 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5123) UreF PF01730.16 GBG91525.1 - 1.3 9.7 6.0 5.1 7.7 2.6 2.6 2 0 0 2 2 2 0 UreF HSP20 PF00011.21 GBG91526.1 - 1.6e-26 92.4 0.6 4.3e-26 91.0 0.6 1.7 1 0 0 1 1 1 1 Hsp20/alpha crystallin family RT_RNaseH_2 PF17919.1 GBG91526.1 - 5.2e-25 87.4 0.0 1.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91526.1 - 9.3e-25 87.0 0.0 1.8e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91526.1 - 3.8e-22 78.9 0.1 6.2e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArsA_HSP20 PF17886.1 GBG91526.1 - 2e-06 27.2 0.0 4.8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 HSP20-like domain found in ArsA SDA1 PF05285.12 GBG91526.1 - 2.5 7.4 22.8 4.1 6.7 22.8 1.2 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 GBG91526.1 - 2.9 8.1 13.3 4.9 7.4 13.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated RVT_1 PF00078.27 GBG91527.1 - 1.3e-24 87.0 0.0 2.1e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91528.1 - 9.8e-22 76.9 0.1 3.4e-21 75.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91528.1 - 6.5e-20 71.4 0.0 1.6e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91528.1 - 6.8e-20 70.9 0.1 1.3e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG91528.1 - 2.6e-11 43.5 0.2 2.9e-10 40.0 0.0 2.5 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG91528.1 - 4.2e-08 33.4 0.0 1.7e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG91528.1 - 5.4e-06 27.0 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG91528.1 - 1.3e-05 25.0 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Tudor-knot PF11717.8 GBG91528.1 - 0.00014 21.6 0.0 0.00045 20.1 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain gag-asp_proteas PF13975.6 GBG91528.1 - 0.0054 17.3 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG91528.1 - 0.031 14.5 0.0 0.15 12.4 0.0 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG91528.1 - 0.032 14.0 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Chromo PF00385.24 GBG91528.1 - 0.045 13.7 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG91528.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG91529.1 - 7.2e-32 110.7 0.1 1.3e-31 109.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91530.1 - 1.7e-11 44.0 1.0 4.6e-11 42.7 1.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG91530.1 - 3.1e-07 30.6 0.4 6.3e-07 29.6 0.4 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG91530.1 - 0.00011 22.3 0.0 0.00028 21.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG91530.1 - 0.00041 20.1 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG91530.1 - 0.018 14.6 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) EMP70 PF02990.16 GBG91531.1 - 1.3e-76 258.3 24.5 1.9e-76 257.9 24.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Retrotrans_gag PF03732.17 GBG91531.1 - 0.021 15.1 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein DUF659 PF04937.15 GBG91533.1 - 3.9e-08 33.3 0.0 6.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Fib_alpha PF08702.10 GBG91535.1 - 2 8.6 10.4 0.31 11.2 2.9 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LPP PF04728.13 GBG91535.1 - 4 7.9 14.5 6.6 7.2 0.0 5.1 5 1 0 5 5 5 0 Lipoprotein leucine-zipper SKG6 PF08693.10 GBG91537.1 - 0.037 13.5 0.0 0.12 11.8 0.0 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PRIMA1 PF16101.5 GBG91538.1 - 0.5 10.4 5.2 0.33 11.0 0.6 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SGL PF08450.12 GBG91539.1 - 0.11 12.0 0.0 10 5.6 0.0 2.7 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region DUF1180 PF06679.12 GBG91539.1 - 1.3 9.4 8.0 14 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Pkinase_Tyr PF07714.17 GBG91540.1 - 7.3e-40 136.9 0.0 1.2e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG91540.1 - 2.8e-37 128.5 0.0 4.7e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG91540.1 - 0.00019 21.4 0.0 0.0011 19.0 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG91540.1 - 0.0097 14.7 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PHC2_SAM_assoc PF16616.5 GBG91540.1 - 1.1 10.0 4.1 2.1 9.1 4.1 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Rrn6 PF10214.9 GBG91540.1 - 2.8 6.3 5.4 4.3 5.7 5.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF659 PF04937.15 GBG91541.1 - 1.7e-05 24.7 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91541.1 - 1.9e-05 24.4 1.5 4.6e-05 23.1 0.9 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AT_hook PF02178.19 GBG91541.1 - 0.64 10.1 7.6 2.9 8.1 7.6 2.3 1 0 0 1 1 1 0 AT hook motif Asp_protease_2 PF13650.6 GBG91544.1 - 0.055 14.1 0.1 0.2 12.3 0.1 2.0 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG91544.1 - 0.079 13.5 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG91544.1 - 0.084 13.0 2.3 0.15 12.2 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG91544.1 - 0.12 12.1 0.3 0.3 10.8 0.3 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DUF659 PF04937.15 GBG91545.1 - 4.7e-13 49.3 0.2 9.1e-13 48.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SURF2 PF05477.11 GBG91547.1 - 5 6.8 4.9 4.5 6.9 3.2 1.8 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SGL PF08450.12 GBG91550.1 - 0.036 13.6 0.0 0.58 9.7 0.0 2.4 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Shisa PF13908.6 GBG91550.1 - 0.078 13.2 0.0 0.078 13.2 0.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SKG6 PF08693.10 GBG91550.1 - 0.61 9.5 4.7 1.3 8.5 4.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 GBG91550.1 - 1.7 8.5 6.1 2.8 7.8 6.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PRIMA1 PF16101.5 GBG91550.1 - 2.3 8.3 18.8 1.6e+02 2.4 19.5 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 GBG91551.1 - 2.6e-18 66.3 0.0 2.1e-17 63.3 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain WD40 PF00400.32 GBG91551.1 - 3e-10 40.5 4.1 0.0016 19.2 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF4748 PF15932.5 GBG91551.1 - 0.00093 18.9 3.1 0.0018 18.0 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4748) Nup160 PF11715.8 GBG91551.1 - 0.029 13.0 3.3 3.2 6.3 0.0 3.3 3 1 0 4 4 4 0 Nucleoporin Nup120/160 Saccharop_dh_N PF04455.12 GBG91551.1 - 0.049 14.0 0.5 0.2 12.1 0.5 2.1 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region Sec20 PF03908.13 GBG91551.1 - 0.31 11.0 8.8 0.06 13.3 2.0 3.0 2 1 1 3 3 3 0 Sec20 Glyco_hydro_67N PF03648.14 GBG91551.1 - 1.5 9.1 4.0 1.4 9.2 1.2 2.4 1 1 1 2 2 2 0 Glycosyl hydrolase family 67 N-terminus DUF2730 PF10805.8 GBG91551.1 - 7.3 6.7 11.2 13 5.9 2.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Pkinase PF00069.25 GBG91552.1 - 1.7e-19 70.2 0.0 1.7e-19 70.2 0.0 2.4 2 1 1 3 3 3 1 Protein kinase domain WD40 PF00400.32 GBG91552.1 - 7.9e-09 36.0 3.4 0.014 16.3 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG91552.1 - 7.8e-06 26.1 0.3 0.19 12.1 0.1 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GBG91552.1 - 0.0022 16.7 1.3 1.5 7.4 0.0 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Sec20 PF03908.13 GBG91552.1 - 0.012 15.6 9.0 0.041 13.8 4.9 2.5 1 1 1 2 2 2 0 Sec20 FAM101 PF15068.6 GBG91552.1 - 0.084 12.8 0.4 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 FAM101 family V_ATPase_I PF01496.19 GBG91552.1 - 1.3 6.9 17.6 3.1 5.6 17.3 1.6 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family WD40_alt PF14077.6 GBG91552.1 - 6.8 6.6 6.0 20 5.1 0.5 3.2 1 1 2 3 3 3 0 Alternative WD40 repeat motif GIY-YIG PF01541.24 GBG91554.1 - 0.0012 19.1 0.0 0.004 17.4 0.0 1.9 1 0 0 1 1 1 1 GIY-YIG catalytic domain YojJ PF10372.9 GBG91554.1 - 0.14 12.3 1.3 0.35 11.0 0.2 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus ARA70 PF12489.8 GBG91554.1 - 1.2 9.3 4.9 0.21 11.8 0.3 2.1 3 0 0 3 3 3 0 Nuclear coactivator CP12 PF02672.15 GBG91554.1 - 5.8 7.7 6.8 40 5.1 0.1 2.8 2 0 0 2 2 2 0 CP12 domain CheY-binding PF09078.11 GBG91555.1 - 0.0062 16.6 0.5 0.019 15.1 0.1 2.0 2 0 0 2 2 2 1 CheY binding F-112 PF09645.10 GBG91555.1 - 0.065 13.4 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 F-112 protein PIEZO PF15917.5 GBG91555.1 - 0.33 10.4 7.7 0.064 12.7 3.3 1.9 2 0 0 2 2 2 0 Piezo DUF4164 PF13747.6 GBG91555.1 - 3.8 7.8 14.6 1.4 9.3 6.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) TraP PF07296.11 GBG91556.1 - 0.037 13.2 0.0 0.1 11.8 0.0 1.7 1 0 0 1 1 1 0 TraP protein DDE_Tnp_4 PF13359.6 GBG91558.1 - 1.1e-31 109.7 0.0 3.4e-31 108.1 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91558.1 - 4.3e-16 59.1 0.0 7.9e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91558.1 - 0.00066 19.4 0.9 0.31 10.6 0.0 3.3 4 0 0 4 4 4 2 Transposase DDE domain DDE_Tnp_4 PF13359.6 GBG91559.1 - 7.8e-28 97.1 0.0 2.5e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91559.1 - 2.4e-11 43.6 0.0 7.2e-11 42.1 0.0 1.7 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91559.1 - 0.00057 19.6 0.1 4.6 6.8 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain IL4_i_Ig PF18258.1 GBG91560.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain Nucleotid_trans PF03407.16 GBG91561.1 - 1.3e-19 71.0 0.0 1.7e-18 67.4 0.0 2.2 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase TilS PF09179.11 GBG91561.1 - 0.011 16.2 0.4 0.41 11.2 0.0 2.8 3 0 0 3 3 3 0 TilS substrate binding domain Myb_DNA-bind_4 PF13837.6 GBG91562.1 - 1.8e-06 28.3 0.9 6.4e-06 26.5 0.9 2.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG91562.1 - 0.0032 17.5 0.2 0.009 16.1 0.2 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG91562.1 - 0.034 14.4 0.9 2.5 8.4 0.1 2.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GBG91563.1 - 2.7e-08 34.1 2.0 2.7e-08 34.1 2.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG91563.1 - 0.0013 18.8 0.6 0.0028 17.7 0.6 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91563.1 - 0.0022 18.3 1.7 0.011 16.0 0.4 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Defensin_big PF14862.6 GBG91563.1 - 0.72 10.2 2.9 1.9 8.9 0.0 3.1 3 0 0 3 3 3 0 Big defensin zf-CCHC PF00098.23 GBG91564.1 - 0.0016 18.5 2.2 0.0032 17.5 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG91564.1 - 0.007 16.2 6.1 0.013 15.3 6.1 1.3 1 0 0 1 1 1 1 Zinc knuckle E7 PF00527.18 GBG91564.1 - 3.9 7.7 8.3 9.9 6.4 2.4 2.9 2 0 0 2 2 2 0 E7 protein, Early protein Nucleotid_trans PF03407.16 GBG91566.1 - 2.1e-21 76.9 0.0 3.2e-20 73.0 0.0 2.1 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase RVP_2 PF08284.11 GBG91567.1 - 6.7e-09 35.6 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG91567.1 - 4.5e-08 32.9 0.0 8.8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91567.1 - 8.5e-08 32.7 0.0 2.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91567.1 - 4.2e-06 27.2 0.0 1.1e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG91567.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG91567.1 - 0.043 14.1 1.6 0.77 10.1 0.1 3.6 3 0 0 3 3 3 0 Retrotransposon gag protein TAF4 PF05236.14 GBG91567.1 - 0.28 10.9 7.7 0.6 9.8 7.7 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4187 PF13821.6 GBG91567.1 - 0.39 10.5 2.1 1.4 8.8 2.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DUF4360 PF14273.6 GBG91569.1 - 7.5e-31 107.4 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Sec1 PF00995.23 GBG91570.1 - 7.6e-32 111.3 0.0 1.1e-31 110.7 0.0 1.2 1 0 0 1 1 1 1 Sec1 family RVT_1 PF00078.27 GBG91570.1 - 4e-25 88.6 0.1 8.3e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91570.1 - 9e-17 60.9 0.2 2.3e-16 59.6 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG91570.1 - 1e-10 41.9 0.0 2.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG91570.1 - 7.7e-05 22.9 0.0 0.00023 21.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG91570.1 - 0.002 18.1 0.0 0.0049 16.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG91570.1 - 0.034 14.4 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG91571.1 - 3e-34 117.0 0.0 6.7e-34 115.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91571.1 - 1.1e-31 109.2 0.1 2.5e-31 108.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91571.1 - 2.3e-11 43.6 0.0 6.1e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG91571.1 - 4.2e-11 42.8 0.2 8.4e-11 41.8 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG91571.1 - 0.012 15.8 0.1 0.048 13.8 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain Sec1 PF00995.23 GBG91572.1 - 7.9e-24 84.8 0.0 1.2e-23 84.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family RVT_1 PF00078.27 GBG91573.1 - 9.5e-13 48.2 0.4 4.8e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG91573.1 - 6.9e-07 29.1 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG91573.1 - 1.7e-05 24.8 0.0 0.00019 21.4 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG91573.1 - 2.1e-05 25.1 0.0 5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91573.1 - 0.00015 22.2 0.4 0.00065 20.2 0.0 2.3 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG91573.1 - 0.0038 17.0 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG91573.1 - 0.016 15.0 0.0 0.078 12.8 0.0 2.0 2 1 0 2 2 2 0 Aspartyl protease HemY_N PF07219.13 GBG91574.1 - 0.23 11.7 1.9 0.19 11.9 0.4 1.5 2 0 0 2 2 2 0 HemY protein N-terminus Myb_DNA-bind_4 PF13837.6 GBG91575.1 - 5.2e-07 30.0 1.3 1.3e-06 28.7 0.5 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91575.1 - 0.1 12.9 0.2 0.22 11.8 0.2 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase PF00069.25 GBG91576.1 - 1.4e-30 106.6 0.0 2.3e-30 105.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91576.1 - 1.9e-30 106.0 0.0 1.2e-29 103.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG91576.1 - 0.0021 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG91576.1 - 0.048 13.6 0.0 0.094 12.6 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2510 PF10708.9 GBG91578.1 - 2.7 7.8 7.1 2.4 8.0 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2510) RVT_1 PF00078.27 GBG91579.1 - 2.1e-22 79.7 0.0 4.1e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG91579.1 - 2.2e-05 24.3 3.9 2.2e-05 24.3 3.9 2.2 2 0 0 2 2 2 1 Zinc knuckle ArAE_2_N PF10337.9 GBG91579.1 - 1.6 7.7 3.5 2.4 7.1 3.5 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal SpoVR PF04293.13 GBG91579.1 - 2.6 6.6 7.9 4.1 6.0 7.9 1.2 1 0 0 1 1 1 0 SpoVR like protein zf-CCHC_2 PF13696.6 GBG91579.1 - 4.5 7.2 7.0 2.6 7.9 4.2 2.2 2 0 0 2 2 2 0 Zinc knuckle Vfa1 PF08432.10 GBG91579.1 - 8.1 6.7 16.9 22 5.3 16.9 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pkinase_Tyr PF07714.17 GBG91580.1 - 2.1e-40 138.7 0.0 1.2e-27 96.9 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG91580.1 - 3.2e-39 134.9 0.0 1.3e-28 100.1 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain RVP_2 PF08284.11 GBG91580.1 - 2.8e-08 33.6 0.0 6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91580.1 - 1.9e-07 31.6 0.0 1.1e-06 29.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91580.1 - 6.3e-06 26.7 0.0 2.7e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease APH PF01636.23 GBG91580.1 - 0.0012 18.8 0.0 0.03 14.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG91580.1 - 0.0077 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Asp_protease PF09668.10 GBG91580.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF4653 PF15546.6 GBG91580.1 - 0.053 13.2 1.1 9.5 5.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) MscS_porin PF12795.7 GBG91580.1 - 1.2 8.6 7.4 2.4 7.7 7.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TolA_bind_tri PF16331.5 GBG91580.1 - 2.5 8.3 4.7 5.7 7.1 4.7 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation PRA1 PF03208.19 GBG91581.1 - 0.42 10.2 12.0 0.5 10.0 12.0 1.1 1 0 0 1 1 1 0 PRA1 family protein S-AdoMet_synt_C PF02773.16 GBG91583.1 - 9.4e-64 213.5 0.4 2.4e-63 212.2 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GBG91583.1 - 2.5e-46 156.8 0.0 4.1e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GBG91583.1 - 9.6e-42 141.7 0.2 1.8e-41 140.8 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain DUF659 PF04937.15 GBG91584.1 - 5.6e-13 49.0 0.1 6.7e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Rhodanese PF00581.20 GBG91585.1 - 3.8e-11 43.4 0.0 5.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain PRTP PF01366.18 GBG91585.1 - 0.13 10.3 0.0 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein CemA PF03040.14 GBG91587.1 - 2.3 8.1 7.9 4.5 7.2 7.9 1.4 1 0 0 1 1 1 0 CemA family Exonuc_VII_L PF02601.15 GBG91587.1 - 2.5 7.6 18.3 4.6 6.7 13.0 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit TFIIA PF03153.13 GBG91587.1 - 8.5 6.3 69.3 0.016 15.2 29.5 3.3 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit DDE_Tnp_4 PF13359.6 GBG91588.1 - 9.7e-21 74.1 0.0 1.3e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91588.1 - 2.6e-12 46.8 0.0 3.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Glutaredoxin2_C PF04399.13 GBG91588.1 - 0.053 13.4 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DDE_Tnp_1 PF01609.21 GBG91588.1 - 0.19 11.4 0.6 0.37 10.4 0.2 1.6 2 0 0 2 2 2 0 Transposase DDE domain DUF4681 PF15732.5 GBG91590.1 - 0.053 13.8 2.0 0.055 13.7 1.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4681) Sua5_yciO_yrdC PF01300.18 GBG91590.1 - 0.16 11.5 1.0 0.2 11.2 1.0 1.1 1 0 0 1 1 1 0 Telomere recombination FHIPEP PF00771.20 GBG91590.1 - 0.56 8.6 4.7 0.64 8.4 4.7 1.0 1 0 0 1 1 1 0 FHIPEP family DUF572 PF04502.13 GBG91590.1 - 4 7.0 12.5 4 7.0 12.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Integrase_H2C2 PF17921.1 GBG91591.1 - 7.7e-12 45.2 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain HOIP-UBA PF16678.5 GBG91591.1 - 0.074 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair TPR_14 PF13428.6 GBG91592.1 - 0.01 16.6 0.4 0.064 14.1 0.4 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Glyco_transf_34 PF05637.12 GBG91593.1 - 4e-27 95.5 0.0 2.7e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 GBG91593.1 - 3.4e-05 23.5 0.0 0.33 10.5 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 GBG91593.1 - 0.058 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_tranf_2_4 PF13704.6 GBG91593.1 - 0.088 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 AP2 PF00847.20 GBG91596.1 - 7.6e-16 58.1 8.3 1.1e-08 35.1 1.3 3.0 2 0 0 2 2 2 2 AP2 domain AP2 PF00847.20 GBG91597.1 - 6.7e-16 58.3 8.3 1.1e-08 35.2 1.3 3.0 2 0 0 2 2 2 2 AP2 domain AP2 PF00847.20 GBG91598.1 - 7.6e-16 58.1 8.3 1.1e-08 35.1 1.3 3.0 2 0 0 2 2 2 2 AP2 domain Reticulon PF02453.17 GBG91599.1 - 1.5e-44 151.8 7.1 2.4e-44 151.1 7.1 1.3 1 0 0 1 1 1 1 Reticulon ER_lumen_recept PF00810.18 GBG91599.1 - 0.026 15.3 0.3 0.026 15.3 0.3 1.8 2 0 0 2 2 2 0 ER lumen protein retaining receptor ubiquitin PF00240.23 GBG91600.1 - 0.00039 20.1 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 GBG91600.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GBG91601.1 - 0.00046 19.9 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 GBG91601.1 - 0.0017 18.5 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Lipoxygenase PF00305.19 GBG91602.1 - 0.056 11.9 0.1 0.084 11.3 0.1 1.2 1 0 0 1 1 1 0 Lipoxygenase Acyl-ACP_TE PF01643.17 GBG91603.1 - 1.1e-70 237.7 0.0 5.6e-69 232.2 0.0 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 GBG91603.1 - 0.013 16.0 0.3 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Thioesterase-like superfamily EMI PF07546.13 GBG91603.1 - 0.5 11.2 3.1 0.53 11.1 0.9 2.1 2 0 0 2 2 2 0 EMI domain RVT_1 PF00078.27 GBG91605.1 - 2.9e-34 118.6 0.1 4.9e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91605.1 - 1.1e-30 105.6 0.0 2.4e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91605.1 - 8.5e-30 103.1 0.1 1.6e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG91605.1 - 1.2e-06 28.3 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91605.1 - 4.2e-06 27.3 0.0 9.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91605.1 - 0.00016 22.2 0.0 0.00043 20.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG91605.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) FAM220 PF15487.6 GBG91605.1 - 9 5.8 7.5 14 5.3 0.0 3.1 3 0 0 3 3 3 0 FAM220 family Ribonuc_red_lgC PF02867.15 GBG91608.1 - 2e-186 620.6 0.0 2.4e-186 620.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GBG91608.1 - 6.3e-24 83.8 0.0 2.2e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ING PF12998.7 GBG91608.1 - 0.0053 17.3 0.1 0.015 15.8 0.1 1.8 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Peptidase_M24 PF00557.24 GBG91609.1 - 4.9e-39 134.2 0.0 6.2e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3377 PF11857.8 GBG91610.1 - 0.079 12.9 0.0 0.079 12.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Flp1_like PF16982.5 GBG91610.1 - 7.7 6.0 7.8 22 4.5 7.8 1.7 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain rve PF00665.26 GBG91611.1 - 4.7e-09 36.5 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Jnk-SapK_ap_N PF09744.9 GBG91611.1 - 0.00061 20.0 6.3 0.0017 18.6 6.3 1.7 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 GBG91611.1 - 0.076 13.1 9.2 0.18 11.8 9.2 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PriC PF07445.12 GBG91611.1 - 0.13 12.1 3.3 0.26 11.2 3.3 1.4 1 0 0 1 1 1 0 Primosomal replication protein priC Muted PF14942.6 GBG91611.1 - 0.25 11.7 3.1 0.56 10.6 3.1 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Dimer_Tnp_hAT PF05699.14 GBG91613.1 - 0.0037 17.0 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region KxDL PF10241.9 GBG91615.1 - 4.8e-23 81.2 0.0 6e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein NAGLU_C PF12972.7 GBG91615.1 - 0.22 11.0 0.0 0.29 10.6 0.0 1.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain zf-CCHC_4 PF14392.6 GBG91616.1 - 0.09 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG91616.1 - 0.12 12.5 0.5 0.24 11.5 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle NifQ PF04891.12 GBG91616.1 - 0.78 10.1 3.6 2.1 8.7 0.7 2.7 1 1 1 2 2 2 0 NifQ RT_RNaseH_2 PF17919.1 GBG91618.1 - 1.9e-24 85.6 0.0 7.2e-24 83.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91618.1 - 2e-21 76.3 0.0 4.6e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG91618.1 - 0.00016 21.9 6.5 0.0033 17.7 0.3 3.7 4 0 0 4 4 4 2 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG91620.1 - 7.3e-35 119.0 0.1 3.4e-34 116.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91620.1 - 5.2e-31 107.9 0.0 8.7e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91620.1 - 1.1e-28 99.5 0.1 3.4e-28 98.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase MarR_2 PF12802.7 GBG91620.1 - 0.051 13.5 0.0 6.3 6.8 0.0 2.6 2 0 0 2 2 2 0 MarR family MarR PF01047.22 GBG91620.1 - 0.073 13.0 0.2 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 MarR family Retrotrans_gag PF03732.17 GBG91620.1 - 0.11 12.7 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein HTH_24 PF13412.6 GBG91620.1 - 0.39 10.3 2.5 4.6 6.9 0.4 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding RVT_1 PF00078.27 GBG91621.1 - 2.7e-32 112.1 0.1 4.8e-32 111.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91621.1 - 2.4e-30 104.5 0.0 4.7e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91621.1 - 8.9e-27 93.4 0.0 2.4e-26 92.1 0.1 1.8 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91621.1 - 1.8e-15 56.8 0.1 9e-15 54.5 0.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG91621.1 - 2e-14 53.8 0.0 4.3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Root_cap PF06830.11 GBG91621.1 - 2.1e-09 37.4 0.1 1.2e-08 35.0 0.1 2.2 1 1 0 1 1 1 1 Root cap RVP_2 PF08284.11 GBG91621.1 - 1.4e-07 31.3 0.0 2.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91621.1 - 0.00045 20.8 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG91621.1 - 0.00067 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91621.1 - 0.00085 19.8 0.0 0.0059 17.1 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG91621.1 - 0.0064 16.7 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger Rhamno_transf PF11316.8 GBG91621.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase RVT_1 PF00078.27 GBG91622.1 - 2.4e-27 95.9 0.0 7.7e-27 94.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA PF00004.29 GBG91623.1 - 6.2e-13 49.3 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Myb_DNA-bind_4 PF13837.6 GBG91623.1 - 7.8e-10 39.0 1.2 4.3e-09 36.6 1.0 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Torsin PF06309.11 GBG91623.1 - 0.016 15.3 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Torsin DUF1654 PF07867.11 GBG91623.1 - 0.11 12.3 0.9 19 5.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) MADF_DNA_bdg PF10545.9 GBG91623.1 - 0.15 12.4 0.1 0.41 11.0 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Histone PF00125.24 GBG91624.1 - 5.1e-23 81.9 0.3 1.6e-22 80.3 0.1 1.9 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GBG91624.1 - 0.82 9.8 3.6 1.3 9.1 0.3 2.3 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit RAP1 PF07218.11 GBG91627.1 - 0.016 13.5 4.3 0.026 12.8 4.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pex14_N PF04695.13 GBG91627.1 - 0.054 14.1 11.2 0.046 14.4 1.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S64 PF08192.11 GBG91627.1 - 0.055 12.0 1.1 0.074 11.5 1.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Tmemb_cc2 PF10267.9 GBG91627.1 - 0.055 12.6 2.1 0.08 12.1 2.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Miga PF10265.9 GBG91627.1 - 0.2 10.6 4.3 0.29 10.1 4.3 1.2 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 GBG91627.1 - 7.4 5.3 9.5 11 4.7 9.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain F-box-like PF12937.7 GBG91628.1 - 3.2e-08 33.3 0.1 2e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GBG91628.1 - 2.5e-05 24.5 0.8 0.027 14.9 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG91628.1 - 3.8e-05 23.4 0.1 9.4e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain RVT_1 PF00078.27 GBG91629.1 - 2.4e-23 82.8 0.0 4e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91629.1 - 3.8e-23 81.4 0.0 8e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91629.1 - 2.6e-11 43.8 0.0 5.4e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Casc1_N PF15927.5 GBG91631.1 - 0.059 13.0 14.7 0.046 13.4 13.1 1.6 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus MREG PF15812.5 GBG91631.1 - 0.44 10.8 4.2 0.83 10.0 4.2 1.4 1 0 0 1 1 1 0 Melanoregulin RT_RNaseH_2 PF17919.1 GBG91633.1 - 1.7e-26 92.2 0.0 4.7e-26 90.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91633.1 - 2.3e-25 89.4 0.1 3.8e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91633.1 - 3.7e-25 88.2 0.0 8e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ST7 PF04184.12 GBG91633.1 - 0.14 10.6 0.1 0.2 10.1 0.1 1.1 1 0 0 1 1 1 0 ST7 protein zf-CCHC_2 PF13696.6 GBG91634.1 - 0.047 13.5 0.2 0.047 13.5 0.2 2.1 2 0 0 2 2 2 0 Zinc knuckle ABC1 PF03109.16 GBG91635.1 - 3.2e-23 82.2 0.0 7.9e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GBG91635.1 - 0.00029 20.8 0.2 0.0015 18.5 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 GBG91635.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RVT_1 PF00078.27 GBG91638.1 - 5.1e-34 117.7 0.1 9e-34 116.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91638.1 - 2.1e-28 98.7 0.1 5.9e-28 97.2 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91638.1 - 1.3e-27 95.7 0.0 3.5e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG91639.1 - 4e-05 24.1 0.0 8.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91639.1 - 0.00051 20.6 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG91639.1 - 0.022 14.5 0.4 0.039 13.7 0.4 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF1844 PF08899.11 GBG91639.1 - 0.17 12.2 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) Pkinase PF00069.25 GBG91640.1 - 5.1e-27 94.9 0.0 8.6e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91640.1 - 1.8e-15 56.9 0.0 2.6e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG91640.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF659 PF04937.15 GBG91641.1 - 1.6e-18 67.0 0.0 3.9e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG91643.1 - 2.8e-10 40.1 0.0 4.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG91643.1 - 6.6e-07 29.8 0.1 1.5e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91643.1 - 4.8e-05 23.9 0.1 0.0001 22.9 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG91643.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG91643.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Peptidase_C48 PF02902.19 GBG91644.1 - 1.7e-26 93.5 0.0 2.6e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Period_C PF12114.8 GBG91644.1 - 5.9 6.4 7.4 13 5.3 7.4 1.6 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF659 PF04937.15 GBG91645.1 - 2.8e-22 79.2 0.0 4.6e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) UPF0561 PF10573.9 GBG91645.1 - 0.14 12.3 6.4 1.4 9.1 0.2 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0561 DUF659 PF04937.15 GBG91646.1 - 1.1e-33 116.2 0.0 1.7e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Myb_DNA-bind_4 PF13837.6 GBG91647.1 - 1.1e-14 54.6 1.0 1.8e-14 53.8 1.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG91647.1 - 4.5e-05 23.6 0.3 8.7e-05 22.6 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GBG91647.1 - 0.035 14.4 0.2 0.069 13.4 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 GBG91647.1 - 0.039 14.9 0.2 0.071 14.1 0.2 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG91647.1 - 0.053 13.6 0.2 0.096 12.8 0.2 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91647.1 - 0.058 13.7 0.2 0.14 12.5 0.2 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase_Tyr PF07714.17 GBG91648.1 - 1.3e-32 113.1 0.0 3.1e-32 111.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG91648.1 - 3.9e-29 101.8 0.0 5e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG91648.1 - 7.9e-05 22.7 0.0 0.00028 20.9 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG91648.1 - 0.00075 18.4 0.0 0.001 17.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF5316 PF17247.2 GBG91649.1 - 0.44 10.6 0.1 0.44 10.6 0.1 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF5316) Sec23_trunk PF04811.15 GBG91650.1 - 9.6e-76 254.5 0.0 1.4e-75 254.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GBG91650.1 - 6.6e-24 83.7 0.0 1.4e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GBG91650.1 - 2.6e-19 69.0 5.5 1.1e-17 63.8 3.2 2.6 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger DUF659 PF04937.15 GBG91650.1 - 1.7e-16 60.5 0.0 3.5e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Sec23_BS PF08033.12 GBG91650.1 - 1.5e-12 48.1 0.0 5e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 GBG91650.1 - 6.8e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Root_cap PF06830.11 GBG91651.1 - 1e-08 35.1 0.1 0.00016 21.7 0.0 2.5 2 0 0 2 2 2 2 Root cap PAN_4 PF14295.6 GBG91651.1 - 0.0001 22.1 2.8 0.0001 22.1 2.8 2.2 2 1 0 2 2 2 1 PAN domain zf-CCHC PF00098.23 GBG91652.1 - 0.00017 21.5 2.4 0.0003 20.7 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG91652.1 - 0.009 15.7 1.2 0.019 14.6 1.2 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger DUF4724 PF15852.5 GBG91652.1 - 0.89 10.1 2.9 0.89 10.1 1.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4724) YqfQ PF14181.6 GBG91652.1 - 2 8.6 9.8 4.2 7.6 9.8 1.5 1 0 0 1 1 1 0 YqfQ-like protein GTP-bdg_N PF13167.6 GBG91653.1 - 5.8e-32 110.2 0.0 1.3e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal RVT_1 PF00078.27 GBG91653.1 - 6.9e-28 97.7 0.1 9.8e-28 97.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG91653.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG91654.1 - 0.0046 17.2 0.3 0.0046 17.2 0.3 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein TcdB_toxin_midC PF12255.8 GBG91654.1 - 0.05 13.7 0.9 1.4 9.0 0.5 2.4 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/C-terminal region DUF4187 PF13821.6 GBG91654.1 - 0.42 10.4 2.5 1.2 8.9 2.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) MMR_HSR1 PF01926.23 GBG91655.1 - 1.9e-14 53.7 0.0 2.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG91655.1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 GBG91655.1 - 0.0018 18.3 0.1 0.0028 17.8 0.0 1.4 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 GBG91655.1 - 0.0019 17.7 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP-bdg_M PF16360.5 GBG91655.1 - 0.013 16.1 0.5 0.025 15.2 0.5 1.5 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region Ploopntkinase3 PF18751.1 GBG91655.1 - 0.033 14.1 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Roc PF08477.13 GBG91655.1 - 0.048 13.9 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Nup54_57_C PF18570.1 GBG91655.1 - 0.09 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain GTP_EFTU PF00009.27 GBG91655.1 - 0.099 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MobB PF03205.14 GBG91655.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 GBG91655.1 - 0.14 12.5 0.1 0.51 10.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 GBG91655.1 - 0.14 12.3 0.3 0.2 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 GBG91655.1 - 0.18 11.2 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family SRPRB PF09439.10 GBG91655.1 - 0.2 11.1 0.9 0.46 9.9 0.1 2.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit BPL_C PF02237.17 GBG91656.1 - 0.03 14.2 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain RRP7 PF12923.7 GBG91657.1 - 1.6e-18 66.9 13.6 2.6e-16 59.8 7.7 2.9 2 1 1 3 3 3 2 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RNR_inhib PF08591.10 GBG91657.1 - 0.048 15.0 0.2 0.064 14.6 0.2 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase inhibitor Pkinase PF00069.25 GBG91659.1 - 4.1e-33 114.9 0.0 1e-24 87.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91659.1 - 1.8e-30 106.1 0.0 9.9e-30 103.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG91659.1 - 0.0051 16.8 0.0 0.068 13.1 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Piezo_RRas_bdg PF12166.8 GBG91660.1 - 4.3 6.5 5.6 7.1 5.8 5.6 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain IBR PF01485.21 GBG91661.1 - 4.2e-21 74.9 35.6 8.1e-12 45.2 5.6 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain DDE_Tnp_4 PF13359.6 GBG91661.1 - 8.6e-21 74.3 0.0 3.7e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91661.1 - 4.5e-09 36.2 0.0 8.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein zf-RING_5 PF14634.6 GBG91661.1 - 0.0004 20.3 35.2 0.0066 16.4 6.4 3.7 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 GBG91661.1 - 0.0013 18.7 31.1 0.0069 16.4 4.4 3.8 3 1 0 3 3 3 3 RING-type zinc-finger zf-RING_2 PF13639.6 GBG91661.1 - 0.0078 16.5 37.6 0.021 15.1 6.9 4.0 3 2 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 GBG91661.1 - 0.0093 15.8 33.1 0.021 14.7 7.0 4.2 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 GBG91661.1 - 0.073 12.9 31.3 0.05 13.4 8.8 3.8 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain DDE_Tnp_1 PF01609.21 GBG91661.1 - 0.15 11.7 0.2 48 3.5 0.0 3.2 3 0 0 3 3 3 0 Transposase DDE domain zf-C3HC4_2 PF13923.6 GBG91661.1 - 1 9.3 34.6 0.24 11.2 6.8 4.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GBG91661.1 - 5.6 7.2 24.8 0.41 10.8 2.3 3.7 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GBG91661.1 - 8.2 6.4 33.0 2.2 8.2 3.6 4.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 Ribosomal_S6 PF01250.17 GBG91662.1 - 0.12 12.6 0.3 24 5.3 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S6 Myb_DNA-bind_4 PF13837.6 GBG91663.1 - 3.6e-10 40.1 1.5 2.4e-08 34.2 0.2 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91663.1 - 0.23 11.8 0.5 0.57 10.5 0.1 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RT_RNaseH_2 PF17919.1 GBG91664.1 - 3.1e-28 97.7 0.0 5.7e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91664.1 - 2.2e-26 92.2 0.0 3.5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91664.1 - 9.3e-14 51.5 0.1 1.3e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG91664.1 - 0.071 13.0 0.1 0.64 9.9 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) STIL_N PF15253.6 GBG91667.1 - 2.2e-26 92.7 0.0 3.6e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus AAA_25 PF13481.6 GBG91668.1 - 6.9e-15 55.1 0.0 1.6e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GBG91668.1 - 2.3e-10 40.2 1.1 0.00037 19.9 0.0 3.0 1 1 1 2 2 2 2 KaiC ChlI PF13541.6 GBG91668.1 - 7.3e-09 35.5 0.0 3.4e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 GBG91668.1 - 4.9e-08 32.8 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain Rubredoxin_2 PF18073.1 GBG91668.1 - 2.6e-07 30.2 2.9 7.3e-07 28.8 2.9 1.8 1 0 0 1 1 1 1 Rubredoxin metal binding domain DnaB_C PF03796.15 GBG91668.1 - 1.1e-05 24.9 0.0 5.7e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 GBG91668.1 - 0.0011 19.3 0.0 0.0028 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GBG91668.1 - 0.0059 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GBG91668.1 - 0.0075 16.5 0.0 0.019 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 GBG91668.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 GBG91668.1 - 0.016 15.7 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 GBG91668.1 - 0.026 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 NTPase Hpr_kinase_C PF07475.12 GBG91668.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 GBG91668.1 - 0.084 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Isochorismatase PF00857.20 GBG91668.1 - 0.16 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Isochorismatase family Slu7 PF11708.8 GBG91669.1 - 1.1e-89 300.8 5.5 1.1e-89 300.8 5.5 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 GBG91669.1 - 0.11 12.2 0.3 0.26 11.1 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG91670.1 - 1.5e-25 89.1 0.0 2.6e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91670.1 - 1.4e-22 80.0 0.0 2.4e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91670.1 - 1.9e-10 40.7 0.0 4.6e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF2851 PF11013.8 GBG91670.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) Baculo_PEP_C PF04513.12 GBG91671.1 - 0.0029 17.6 0.3 1.6 8.8 0.0 2.3 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus ANAPC15 PF15243.6 GBG91671.1 - 3.2 8.2 16.5 14 6.2 12.1 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 NOA36 PF06524.12 GBG91671.1 - 4.6 6.5 10.1 9.3 5.5 10.1 1.5 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG91672.1 - 0.058 11.5 7.0 0.089 10.9 7.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi DUF4820 PF16091.5 GBG91672.1 - 0.65 9.3 8.4 0.051 12.9 3.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) NOA36 PF06524.12 GBG91672.1 - 3.5 6.9 10.1 6.4 6.0 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein STAC2_u1 PF16664.5 GBG91672.1 - 5.4 7.5 11.2 0.19 12.2 3.5 2.2 2 1 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 HSP70 PF00012.20 GBG91673.1 - 1.4e-144 482.6 0.0 1.8e-123 412.9 0.0 2.5 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 GBG91673.1 - 1.6e-10 40.3 0.1 4.9e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein HTH_AsnC-type PF13404.6 GBG91673.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PTPRCAP PF15713.5 GBG91673.1 - 0.47 10.7 12.5 0.99 9.7 12.5 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG91673.1 - 8.2 4.6 8.6 12 4.0 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG91674.1 - 0.018 14.6 0.2 0.066 12.7 0.2 1.8 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91675.1 - 1.2e-22 80.2 0.0 2.2e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91675.1 - 5.8e-22 77.6 0.0 9.4e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PTPRCAP PF15713.5 GBG91675.1 - 5.2 7.4 45.6 0.65 10.3 12.5 3.5 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated HSP70 PF00012.20 GBG91677.1 - 1.6e-127 426.2 0.0 2.2e-59 201.2 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 GBG91677.1 - 7.1e-10 38.2 3.1 9.6e-06 24.6 0.2 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GBG91677.1 - 0.00015 21.6 0.1 0.00038 20.2 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG91677.1 - 0.042 14.3 0.5 0.77 10.2 0.0 2.9 3 0 0 3 3 3 0 Cell division protein FtsA YL1 PF05764.13 GBG91678.1 - 0.21 11.7 29.6 0.35 10.9 29.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GBG91678.1 - 5.8 6.2 34.0 8.1 5.8 34.0 1.1 1 0 0 1 1 1 0 SDA1 Acyltransferase PF01553.21 GBG91679.1 - 8.1e-16 57.9 0.0 1.5e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase RT_RNaseH_2 PF17919.1 GBG91679.1 - 1.2e-15 57.4 0.0 2.2e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase EF-hand_1 PF00036.32 GBG91679.1 - 1.3e-15 55.6 5.8 9.8e-05 21.6 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 GBG91679.1 - 7.3e-15 55.2 2.1 1.5e-12 47.8 0.2 2.8 1 1 2 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 GBG91679.1 - 5.4e-14 50.9 2.7 0.00067 19.4 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 GBG91679.1 - 5.2e-12 44.7 5.2 1.3e-05 24.5 0.2 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GBG91679.1 - 1.3e-11 44.1 3.7 4.1e-07 29.7 0.6 3.5 2 1 1 3 3 3 3 EF-hand domain pair RVT_1 PF00078.27 GBG91679.1 - 4.2e-08 33.0 0.1 6.6e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91679.1 - 2.8e-06 27.6 0.0 5.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SPARC_Ca_bdg PF10591.9 GBG91679.1 - 0.02 15.2 0.0 0.02 15.2 0.0 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CDC45 PF02724.14 GBG91679.1 - 0.027 12.8 8.1 0.037 12.3 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein MRNIP PF15749.5 GBG91679.1 - 0.92 10.3 6.3 2.3 9.0 6.3 1.7 1 0 0 1 1 1 0 MRN-interacting protein TFIIF_alpha PF05793.12 GBG91679.1 - 2.4 6.6 23.2 3.8 6.0 23.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 GBG91679.1 - 2.8 6.1 21.6 4 5.5 21.6 1.1 1 0 0 1 1 1 0 Nop14-like family AAA_12 PF13087.6 GBG91680.1 - 1e-60 204.8 0.0 1.8e-60 204.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG91680.1 - 1.1e-46 159.7 2.2 1.1e-46 159.7 2.2 5.7 3 2 0 4 4 4 1 AAA domain zf-CCHC_3 PF13917.6 GBG91680.1 - 5.2e-18 64.7 1.4 1.4e-17 63.4 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle AAA_30 PF13604.6 GBG91680.1 - 2.3e-13 50.3 2.4 1.4e-10 41.3 2.3 2.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG91680.1 - 4.8e-10 39.9 1.5 4.2e-09 36.9 1.5 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GBG91680.1 - 2.3e-07 30.8 0.2 0.033 13.9 0.0 3.6 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase Myc_N PF01056.18 GBG91680.1 - 0.0072 16.3 0.6 0.0072 16.3 0.6 5.5 3 1 2 5 5 5 1 Myc amino-terminal region UvrD_C_2 PF13538.6 GBG91680.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PPR_2 PF13041.6 GBG91681.1 - 2e-77 255.2 8.2 6.3e-12 45.5 0.7 9.4 2 2 7 9 9 9 9 PPR repeat family PPR PF01535.20 GBG91681.1 - 1.1e-71 232.2 15.3 9.9e-09 34.9 0.1 10.6 10 0 0 10 10 10 10 PPR repeat PPR_1 PF12854.7 GBG91681.1 - 1.5e-68 226.1 0.1 4e-08 32.8 0.0 10.3 10 0 0 10 10 10 9 PPR repeat PPR_3 PF13812.6 GBG91681.1 - 3e-48 161.7 0.0 2.9e-11 43.2 0.0 7.2 6 1 3 9 9 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GBG91681.1 - 6.1e-28 97.6 0.2 1.9e-09 37.2 0.0 4.0 2 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GBG91681.1 - 3.8e-09 36.6 10.5 9.2 7.4 0.0 9.6 4 3 6 10 10 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG91681.1 - 4.4e-08 32.6 7.5 0.1 12.7 0.1 7.1 7 1 1 8 8 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 GBG91681.1 - 7.5e-07 29.6 6.8 2.1 8.9 0.0 7.1 7 1 1 8 8 7 2 Tetratricopeptide repeat Clathrin PF00637.20 GBG91681.1 - 4.6e-06 26.5 0.1 0.03 14.2 0.0 4.1 3 1 1 4 4 4 1 Region in Clathrin and VPS TPR_12 PF13424.6 GBG91681.1 - 1.2e-05 25.5 0.2 7.4 6.9 0.0 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GBG91681.1 - 1.3e-05 24.7 2.4 2 8.4 0.1 5.5 7 0 0 7 7 6 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GBG91681.1 - 0.00019 21.4 0.4 19 5.1 0.0 4.9 3 1 2 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.7 GBG91681.1 - 0.0014 18.8 0.0 13 6.1 0.1 3.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ECSIT PF06239.11 GBG91681.1 - 0.0034 16.5 0.3 4.7 6.3 0.6 4.3 3 2 2 5 5 5 1 Evolutionarily conserved signalling intermediate in Toll pathway HrcA_DNA-bdg PF03444.15 GBG91681.1 - 0.0084 15.7 0.0 1.8 8.3 0.0 3.2 3 0 0 3 3 3 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding TPR_2 PF07719.17 GBG91681.1 - 0.02 15.0 15.2 6.2 7.2 0.4 6.9 9 0 0 9 9 8 0 Tetratricopeptide repeat BTAD PF03704.17 GBG91681.1 - 0.028 14.9 6.1 15 6.0 0.1 5.7 4 2 1 6 6 6 0 Bacterial transcriptional activator domain SPOB_a PF14689.6 GBG91681.1 - 0.085 12.6 1.6 24 4.7 0.0 3.7 5 0 0 5 5 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain MRP-S27 PF10037.9 GBG91681.1 - 0.09 11.6 0.0 17 4.1 0.0 2.7 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S27 2_5_RNA_ligase2 PF13563.6 GBG91681.1 - 0.093 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Vps39_1 PF10366.9 GBG91681.1 - 0.17 12.2 0.0 31 4.9 0.0 2.9 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_8 PF13181.6 GBG91681.1 - 5.1 7.6 7.9 1.1e+02 3.4 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 GBG91682.1 - 4.6e-30 104.8 0.0 1.6e-29 103.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG91682.1 - 7.5e-30 104.2 0.0 1.2e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-CCHC_3 PF13917.6 GBG91682.1 - 4.1e-07 29.9 0.1 1.4e-06 28.1 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle LRR_8 PF13855.6 GBG91682.1 - 0.021 14.6 0.4 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat PIP49_C PF12260.8 GBG91682.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 LRRNT_2 PF08263.12 GBG91682.1 - 0.065 13.5 0.1 0.19 12.1 0.1 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain zf-CCHC PF00098.23 GBG91682.1 - 1.6 9.0 7.6 0.19 11.9 1.9 2.4 2 0 0 2 2 2 0 Zinc knuckle Acetyltransf_13 PF13880.6 GBG91684.1 - 5.2e-28 96.8 0.2 1.2e-27 95.7 0.2 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 GBG91684.1 - 0.019 15.4 0.1 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Nop14 PF04147.12 GBG91685.1 - 0.13 10.5 18.1 0.12 10.5 18.1 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG91685.1 - 0.29 10.5 17.4 0.27 10.6 17.4 1.1 1 0 0 1 1 1 0 SDA1 MRNIP PF15749.5 GBG91685.1 - 0.52 11.1 5.4 0.76 10.5 5.4 1.3 1 0 0 1 1 1 0 MRN-interacting protein RR_TM4-6 PF06459.12 GBG91685.1 - 0.56 10.0 8.9 0.58 9.9 8.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.10 GBG91685.1 - 0.68 9.2 14.8 0.68 9.2 14.8 1.2 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 GBG91685.1 - 2.7 7.5 13.9 2.9 7.4 13.9 1.3 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 GBG91685.1 - 4.1 6.1 6.0 4.4 6.0 6.0 1.1 1 0 0 1 1 1 0 Presenilin Mpp10 PF04006.12 GBG91685.1 - 5.4 5.3 22.3 6.7 5.0 22.3 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF659 PF04937.15 GBG91686.1 - 2e-21 76.5 0.0 2.6e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CoA_binding_2 PF13380.6 GBG91687.1 - 0.041 14.4 0.7 0.4 11.2 0.2 2.3 2 0 0 2 2 2 0 CoA binding domain GIY-YIG PF01541.24 GBG91687.1 - 0.23 11.8 1.3 0.99 9.7 0.0 2.4 2 0 0 2 2 2 0 GIY-YIG catalytic domain DDHD PF02862.17 GBG91687.1 - 0.76 9.9 2.9 1.5 8.9 2.9 1.4 1 0 0 1 1 1 0 DDHD domain rve PF00665.26 GBG91688.1 - 0.00058 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Telethonin PF09470.10 GBG91688.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Telethonin protein AAA_6 PF12774.7 GBG91689.1 - 8.2e-155 514.7 0.0 3.1e-154 512.8 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 GBG91689.1 - 1.5e-77 259.2 0.0 6.9e-74 247.3 0.0 3.3 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 GBG91689.1 - 3.5e-27 95.0 0.4 1.6e-26 92.9 0.1 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 GBG91689.1 - 3.6e-21 75.6 0.0 1.3e-06 28.5 0.0 4.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 GBG91689.1 - 5.4e-07 30.1 0.0 0.1 13.0 0.0 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GBG91689.1 - 1.5e-05 25.4 0.2 0.84 10.0 0.0 4.4 4 0 0 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.22 GBG91689.1 - 0.00027 21.3 0.2 0.48 10.8 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 GBG91689.1 - 0.00062 20.1 0.2 1.5 9.1 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 GBG91689.1 - 0.0011 19.5 0.0 0.42 11.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_lid_1 PF17857.1 GBG91689.1 - 0.002 18.3 0.0 0.0055 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsK_SpoIIIE PF01580.18 GBG91689.1 - 0.0037 16.7 0.1 2.2 7.5 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_33 PF13671.6 GBG91689.1 - 0.0084 16.3 0.7 17 5.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 GBG91689.1 - 0.015 15.0 1.6 1.1 8.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 GBG91689.1 - 0.079 12.3 0.5 17 4.7 0.1 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 GBG91689.1 - 0.13 12.0 0.0 7.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 GBG91689.1 - 0.48 9.9 1.9 6.1 6.2 0.1 2.6 3 0 0 3 3 3 0 PhoH-like protein RVT_1 PF00078.27 GBG91691.1 - 9.8e-30 103.7 0.0 1.7e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91691.1 - 7.5e-21 74.0 0.0 2.5e-20 72.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91691.1 - 1.8e-09 37.9 0.0 1.2e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG91691.1 - 2.7e-05 24.0 0.0 6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91691.1 - 3.6e-05 24.3 0.0 8.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91691.1 - 0.00079 19.9 0.2 0.0033 17.9 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG91691.1 - 0.13 12.1 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Cytochrom_C552 PF02335.15 GBG91693.1 - 0.002 17.1 6.6 0.0036 16.3 6.6 1.3 1 0 0 1 1 1 1 Cytochrome c552 DUF4407 PF14362.6 GBG91693.1 - 3.8 6.8 9.7 6.8 5.9 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_transf_5 PF08323.11 GBG91694.1 - 1.1e-65 221.7 0.0 2e-65 220.9 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG91694.1 - 2.1e-10 40.4 0.0 5.7e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG91694.1 - 1.1e-08 35.6 0.0 3.1e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG91694.1 - 3.9e-08 33.5 0.1 1.7e-07 31.4 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GBG91694.1 - 9.6e-06 26.1 1.4 0.00022 21.7 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain HALZ PF02183.18 GBG91694.1 - 0.006 16.8 0.3 0.006 16.8 0.3 5.6 6 0 0 6 6 6 2 Homeobox associated leucine zipper FlaC_arch PF05377.11 GBG91694.1 - 0.095 13.1 18.3 0.81 10.1 0.3 5.4 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) Glyco_trans_4_2 PF13477.6 GBG91694.1 - 0.19 11.8 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase 4-like NPV_P10 PF05531.12 GBG91694.1 - 3.6 8.1 28.0 1.3 9.6 0.1 5.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 GBG91694.1 - 4.7 6.0 47.4 11 4.8 25.1 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF659 PF04937.15 GBG91695.1 - 3.2e-24 85.5 0.0 5.5e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SDA1 PF05285.12 GBG91697.1 - 0.043 13.2 25.4 0.051 13.0 25.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG91697.1 - 0.62 8.2 30.0 0.79 7.9 30.0 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GBG91697.1 - 9.1 4.9 8.6 9.9 4.8 8.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RT_RNaseH PF17917.1 GBG91698.1 - 1.1e-13 51.4 0.0 2.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91698.1 - 1.1e-13 51.1 0.0 2.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG91698.1 - 0.0077 16.3 11.6 0.24 11.6 2.1 2.7 2 0 0 2 2 2 2 Zinc knuckle HemN_C PF06969.16 GBG91698.1 - 0.086 12.9 0.0 23 5.2 0.0 2.5 2 0 0 2 2 2 0 HemN C-terminal domain Corona_nucleoca PF00937.18 GBG91700.1 - 0.021 13.9 0.4 0.036 13.1 0.4 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4900 PF16241.5 GBG91700.1 - 5.7 7.3 12.7 8.5 6.8 0.3 4.3 4 2 1 5 5 5 0 Domain of unknown function (DUF4900) zf-CCHC PF00098.23 GBG91701.1 - 2.1e-08 33.8 3.8 3.5e-08 33.1 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG91701.1 - 0.0051 16.6 0.7 0.0077 16.0 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GBG91701.1 - 0.064 13.1 1.9 0.15 11.9 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG91701.1 - 0.33 10.7 1.3 0.8 9.5 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG91702.1 - 0.00054 19.9 0.2 0.001 19.0 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.8 GBG91704.1 - 0.09 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AAA_8 PF12780.7 GBG91706.1 - 1.1e-87 293.7 0.0 1.1e-87 293.7 0.0 1.5 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 BUD22 PF09073.10 GBG91706.1 - 5e-07 29.4 9.6 6.6e-07 29.0 9.6 1.1 1 0 0 1 1 1 1 BUD22 DUF4746 PF15928.5 GBG91706.1 - 7.4e-05 22.3 6.3 9.6e-05 21.9 6.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) SR-25 PF10500.9 GBG91706.1 - 0.00029 20.5 19.2 0.00044 19.9 19.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Myc_N PF01056.18 GBG91706.1 - 0.00032 20.7 3.9 0.00049 20.1 3.9 1.2 1 0 0 1 1 1 1 Myc amino-terminal region BSP_II PF05432.11 GBG91706.1 - 0.00062 19.6 22.9 0.0009 19.0 22.9 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) PBP_sp32 PF07222.12 GBG91706.1 - 0.00086 18.8 9.8 0.0013 18.2 9.8 1.2 1 0 0 1 1 1 1 Proacrosin binding protein sp32 Eapp_C PF10238.9 GBG91706.1 - 0.0039 17.3 5.2 0.0076 16.3 5.2 1.4 1 0 0 1 1 1 1 E2F-associated phosphoprotein DUF4471 PF14740.6 GBG91706.1 - 0.0041 16.4 0.1 0.0058 15.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) Gti1_Pac2 PF09729.9 GBG91706.1 - 0.0053 16.9 0.2 0.0071 16.5 0.2 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family Presenilin PF01080.17 GBG91706.1 - 0.0061 15.4 1.1 0.0085 14.9 1.1 1.1 1 0 0 1 1 1 1 Presenilin CENP-N PF05238.13 GBG91706.1 - 0.0081 15.5 1.0 0.011 15.1 1.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DDHD PF02862.17 GBG91706.1 - 0.011 15.9 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 DDHD domain FancD2 PF14631.6 GBG91706.1 - 0.019 12.4 6.9 0.026 11.9 6.9 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease STAC2_u1 PF16664.5 GBG91706.1 - 0.032 14.7 1.2 0.055 13.9 1.2 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF2052 PF09747.9 GBG91706.1 - 0.032 14.4 13.2 0.054 13.6 13.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) YqfQ PF14181.6 GBG91706.1 - 0.032 14.4 4.1 0.057 13.6 4.1 1.5 1 0 0 1 1 1 0 YqfQ-like protein Zip PF02535.22 GBG91706.1 - 0.036 13.3 0.7 0.048 12.9 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RAB3GAP2_C PF14656.6 GBG91706.1 - 0.044 12.0 4.1 0.084 11.1 4.1 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus FYDLN_acid PF09538.10 GBG91706.1 - 0.061 14.0 12.3 0.12 13.1 12.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1168 PF06658.12 GBG91706.1 - 0.098 12.5 27.1 0.16 11.7 27.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SAPS PF04499.15 GBG91706.1 - 0.1 11.3 2.0 0.14 10.9 2.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4820 PF16091.5 GBG91706.1 - 0.14 11.5 9.0 0.25 10.7 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) AP3D1 PF06375.11 GBG91706.1 - 0.16 12.2 27.0 0.28 11.4 27.0 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 CDC45 PF02724.14 GBG91706.1 - 0.19 10.0 8.9 0.13 10.5 7.3 1.5 2 0 0 2 2 2 0 CDC45-like protein Pox_Ag35 PF03286.14 GBG91706.1 - 0.27 11.0 22.4 0.53 10.1 22.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF5427 PF10310.9 GBG91706.1 - 0.28 10.1 9.4 0.41 9.5 9.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FAM176 PF14851.6 GBG91706.1 - 0.32 10.6 13.6 0.58 9.8 13.6 1.3 1 0 0 1 1 1 0 FAM176 family DUF4834 PF16118.5 GBG91706.1 - 0.34 11.9 8.2 0.12 13.3 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RXT2_N PF08595.11 GBG91706.1 - 0.65 10.0 11.6 1.1 9.3 11.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF913 PF06025.12 GBG91706.1 - 0.89 8.5 6.9 1.3 7.9 6.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC27 PF09507.10 GBG91706.1 - 1.1 8.6 22.2 1.5 8.1 22.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3987 PF13148.6 GBG91706.1 - 1.2 8.1 6.6 1.7 7.6 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MAP17 PF15807.5 GBG91706.1 - 1.2 9.4 15.2 2.1 8.6 15.2 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RPOL_N PF14700.6 GBG91706.1 - 1.3 8.4 12.1 1.9 7.8 12.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal RPN2_C PF18004.1 GBG91706.1 - 1.8 8.5 26.2 2.9 7.8 26.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNApol_Exo PF18136.1 GBG91706.1 - 1.9 7.5 12.0 3 6.9 12.0 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain V_ATPase_I PF01496.19 GBG91706.1 - 2.6 5.9 11.4 3.7 5.4 11.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SpoIIP PF07454.11 GBG91706.1 - 3.1 7.2 13.6 4.8 6.6 13.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RNA_pol_Rpc4 PF05132.14 GBG91706.1 - 3.4 8.1 11.7 5.6 7.4 11.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Afi1 PF07792.12 GBG91706.1 - 4 7.9 13.0 9 6.8 13.0 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Vfa1 PF08432.10 GBG91706.1 - 4.1 7.7 23.4 6.6 7.0 23.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.12 GBG91706.1 - 4.5 6.5 20.3 7.8 5.8 20.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Protocadherin PF08374.11 GBG91706.1 - 4.7 7.1 6.8 7.3 6.5 6.8 1.3 1 0 0 1 1 1 0 Protocadherin Nop14 PF04147.12 GBG91706.1 - 6.5 4.8 20.8 9.7 4.3 20.8 1.1 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 GBG91706.1 - 8.8 5.0 16.5 14 4.3 16.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2151 PF10221.9 GBG91706.1 - 9.5 4.7 11.6 15 4.0 11.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator PPP4R2 PF09184.11 GBG91706.1 - 9.9 5.6 19.3 16 5.0 19.3 1.2 1 0 0 1 1 1 0 PPP4R2 Dimer_Tnp_hAT PF05699.14 GBG91709.1 - 8.8e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG91710.1 - 1.1e-29 103.6 0.0 1.7e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91710.1 - 5.5e-22 77.7 0.0 1.8e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91710.1 - 6.2e-15 55.0 0.0 1.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF659 PF04937.15 GBG91710.1 - 5.9e-12 45.7 0.0 9.6e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) rve PF00665.26 GBG91710.1 - 1.9e-10 40.9 0.1 2e-09 37.6 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG91710.1 - 3.3e-10 40.2 0.0 6.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG91710.1 - 0.00037 20.6 0.0 0.00084 19.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger NB-ARC PF00931.22 GBG91711.1 - 6.5e-38 130.3 0.0 1.1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 GBG91711.1 - 1.2e-06 28.8 0.0 5.2e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GBG91711.1 - 4.6e-05 23.9 0.1 0.00039 20.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GBG91711.1 - 0.0016 18.4 0.5 0.0073 16.2 0.5 2.2 1 1 0 1 1 1 1 NACHT domain RPW8 PF05659.11 GBG91711.1 - 0.0052 16.5 0.2 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 AAA_18 PF13238.6 GBG91711.1 - 0.021 15.3 0.0 0.076 13.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 GBG91711.1 - 0.026 14.7 0.0 0.084 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GBG91711.1 - 0.027 14.5 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GBG91711.1 - 0.035 14.5 0.2 0.11 12.9 0.1 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 GBG91711.1 - 0.039 14.5 0.2 3.7 8.0 0.2 2.3 2 0 0 2 2 2 0 AAA domain HflK_N PF12221.8 GBG91711.1 - 0.085 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Sigma54_activat PF00158.26 GBG91711.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 GBG91711.1 - 0.1 12.5 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Torsin PF06309.11 GBG91711.1 - 0.14 12.3 0.0 0.84 9.8 0.0 2.3 3 0 0 3 3 3 0 Torsin TsaE PF02367.17 GBG91711.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Nup54 PF13874.6 GBG91711.1 - 0.16 12.0 0.9 3.6 7.7 0.6 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 RT_RNaseH_2 PF17919.1 GBG91712.1 - 1.1e-23 83.1 0.0 7.6e-23 80.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91712.1 - 1.6e-22 79.7 0.0 3.7e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG91712.1 - 4.7e-07 29.7 0.0 9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG91712.1 - 0.0004 20.4 0.0 0.00084 19.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG91712.1 - 0.00055 19.5 0.4 0.02 14.4 0.0 2.5 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91712.1 - 0.0028 18.3 0.0 0.0072 16.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91712.1 - 0.0037 17.8 0.0 0.0082 16.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SlyX PF04102.12 GBG91712.1 - 0.0053 17.4 1.3 0.0053 17.4 1.3 4.2 3 1 1 4 4 4 1 SlyX Integrin_b_cyt PF08725.11 GBG91712.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RNA_polI_A34 PF08208.11 GBG91714.1 - 0.8 9.8 20.1 1 9.4 20.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4662 PF15578.6 GBG91714.1 - 3.6 7.3 8.0 1.2 8.8 5.8 1.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4662) VIR_N PF15912.5 GBG91714.1 - 8.1 6.0 9.9 9.2 5.8 9.9 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal CDC45 PF02724.14 GBG91715.1 - 0.01 14.2 12.1 0.011 14.1 12.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 GBG91715.1 - 0.026 12.7 6.3 0.031 12.4 6.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SDA1 PF05285.12 GBG91715.1 - 0.042 13.3 13.9 0.043 13.2 13.9 1.1 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 GBG91715.1 - 0.091 13.0 14.7 0.14 12.4 14.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 GBG91715.1 - 0.11 11.2 4.3 0.12 11.1 4.3 1.0 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 GBG91715.1 - 0.2 11.0 19.6 0.25 10.7 19.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2052 PF09747.9 GBG91715.1 - 0.92 9.6 18.4 1.5 8.9 18.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Peptidase_C37 PF05416.12 GBG91715.1 - 1.2 7.6 7.0 1.4 7.3 7.0 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DNA_pol_phi PF04931.13 GBG91715.1 - 1.9 6.5 17.5 2.3 6.2 17.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Raftlin PF15250.6 GBG91715.1 - 3.1 6.5 7.5 3.6 6.2 7.5 1.1 1 0 0 1 1 1 0 Raftlin RR_TM4-6 PF06459.12 GBG91715.1 - 3.5 7.4 13.3 4.6 7.0 13.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 GBG91715.1 - 5 6.0 4.4 5.9 5.8 4.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sporozoite_P67 PF05642.11 GBG91715.1 - 5 5.1 11.0 6.2 4.8 11.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DivIVA PF05103.13 GBG91716.1 - 7.5e-05 22.8 0.1 0.11 12.6 0.0 2.3 2 0 0 2 2 2 2 DivIVA protein CRISPR_Cse1 PF09481.10 GBG91716.1 - 0.0042 16.2 0.0 0.091 11.8 0.0 1.9 2 0 0 2 2 2 2 CRISPR-associated protein Cse1 (CRISPR_cse1) BTB PF00651.31 GBG91717.1 - 5e-11 42.8 0.0 1.9e-10 40.9 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain CDC45 PF02724.14 GBG91717.1 - 0.00029 19.3 5.4 0.00029 19.3 5.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Ribosomal_L6e PF01159.19 GBG91717.1 - 0.0019 18.7 1.3 0.0033 17.9 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e SDA1 PF05285.12 GBG91717.1 - 0.0019 17.7 14.6 0.0025 17.3 14.6 1.1 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 GBG91717.1 - 0.002 16.7 13.8 0.0024 16.4 13.8 1.1 1 0 0 1 1 1 1 Mpp10 protein SpoIIP PF07454.11 GBG91717.1 - 0.0024 17.4 1.2 0.0025 17.3 1.2 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) BUD22 PF09073.10 GBG91717.1 - 0.0043 16.5 9.4 0.0052 16.2 9.4 1.1 1 0 0 1 1 1 1 BUD22 PTPRCAP PF15713.5 GBG91717.1 - 0.0056 17.0 15.1 0.01 16.1 15.1 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated DUF2052 PF09747.9 GBG91717.1 - 0.0072 16.5 14.9 0.01 16.0 14.1 1.6 2 0 0 2 2 1 1 Coiled-coil domain containing protein (DUF2052) Sigma70_ner PF04546.13 GBG91717.1 - 0.0079 16.1 10.7 0.014 15.3 10.7 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region RPA43_OB PF17875.1 GBG91717.1 - 0.008 16.8 3.9 0.013 16.1 3.9 1.3 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I DUF913 PF06025.12 GBG91717.1 - 0.011 14.8 2.3 0.013 14.5 1.3 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Sporozoite_P67 PF05642.11 GBG91717.1 - 0.012 13.7 2.6 0.015 13.5 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med17 PF10156.9 GBG91717.1 - 0.013 14.2 5.4 0.016 13.9 5.4 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Nop14 PF04147.12 GBG91717.1 - 0.025 12.8 17.7 0.031 12.5 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF5523 PF17661.1 GBG91717.1 - 0.04 13.6 14.6 0.054 13.2 14.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) FYDLN_acid PF09538.10 GBG91717.1 - 0.045 14.4 11.6 0.071 13.8 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Paf1 PF03985.13 GBG91717.1 - 0.047 12.7 20.7 0.063 12.3 20.7 1.1 1 0 0 1 1 1 0 Paf1 Nop53 PF07767.11 GBG91717.1 - 0.071 12.5 15.9 0.089 12.2 15.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Zip PF02535.22 GBG91717.1 - 0.084 12.1 0.7 0.08 12.1 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 GBG91717.1 - 0.093 12.9 6.1 0.14 12.4 6.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 GBG91717.1 - 0.12 11.5 9.9 0.17 11.1 9.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 GBG91717.1 - 0.15 10.8 3.4 0.18 10.5 3.4 1.1 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 GBG91717.1 - 0.16 11.7 13.9 0.23 11.2 13.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Connexin PF00029.19 GBG91717.1 - 0.21 11.3 4.3 0.31 10.8 4.3 1.2 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 GBG91717.1 - 0.22 11.3 11.6 0.29 10.9 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_3_Rpc31 PF11705.8 GBG91717.1 - 0.23 11.7 21.4 0.32 11.2 21.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Vfa1 PF08432.10 GBG91717.1 - 0.25 11.7 8.3 0.36 11.1 8.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4746 PF15928.5 GBG91717.1 - 0.3 10.5 14.6 0.42 10.0 14.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 GBG91717.1 - 0.36 9.6 4.5 0.4 9.4 4.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_Rpc4 PF05132.14 GBG91717.1 - 0.39 11.1 5.1 0.55 10.7 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 XAP5 PF04921.14 GBG91717.1 - 0.43 10.4 9.4 0.64 9.8 9.4 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator RPN2_C PF18004.1 GBG91717.1 - 0.44 10.4 12.2 0.64 9.9 12.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RXT2_N PF08595.11 GBG91717.1 - 0.54 10.3 10.9 0.87 9.6 10.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PI3K_1B_p101 PF10486.9 GBG91717.1 - 0.6 7.8 8.2 0.76 7.5 8.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1676 PF07898.13 GBG91717.1 - 0.61 10.1 2.8 1.4 8.9 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) RAB3GAP2_C PF14656.6 GBG91717.1 - 0.66 8.1 4.9 0.89 7.7 4.9 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus MCM_bind PF09739.9 GBG91717.1 - 0.76 8.2 6.9 0.97 7.8 6.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor VIT1 PF01988.19 GBG91717.1 - 0.8 9.5 3.6 1.1 9.0 3.6 1.2 1 0 0 1 1 1 0 VIT family DUF4637 PF15470.6 GBG91717.1 - 0.81 9.4 21.5 1.3 8.7 21.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RNA_polI_A34 PF08208.11 GBG91717.1 - 0.83 9.7 12.5 1.2 9.2 12.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4820 PF16091.5 GBG91717.1 - 1.1 8.6 8.7 1.6 8.0 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) BSP_II PF05432.11 GBG91717.1 - 1.2 8.8 26.8 1.8 8.2 26.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) V_ATPase_I PF01496.19 GBG91717.1 - 1.2 6.9 5.8 1.5 6.7 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Auts2 PF15336.6 GBG91717.1 - 1.4 9.0 10.2 2 8.5 10.2 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Tim54 PF11711.8 GBG91717.1 - 1.5 7.5 10.4 2.1 7.1 10.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPP4R2 PF09184.11 GBG91717.1 - 1.6 8.3 20.0 2.3 7.7 20.0 1.2 1 0 0 1 1 1 0 PPP4R2 CobT PF06213.12 GBG91717.1 - 1.7 8.0 20.9 2.5 7.4 20.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 GBG91717.1 - 1.7 6.6 30.2 2.4 6.1 30.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF719 PF05334.13 GBG91717.1 - 2 8.5 9.0 3.1 8.0 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) ORC_WH_C PF18137.1 GBG91717.1 - 2.2 8.3 9.7 3.6 7.7 9.7 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal EIIBC-GUT_N PF03612.14 GBG91717.1 - 3.2 7.5 6.1 5.3 6.7 6.1 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3306 PF11748.8 GBG91717.1 - 3.6 8.5 12.6 6.1 7.7 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) NOA36 PF06524.12 GBG91717.1 - 3.9 6.7 19.9 7.2 5.8 19.9 1.4 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 GBG91717.1 - 7.2 6.3 12.2 12 5.5 11.5 1.7 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH RVT_1 PF00078.27 GBG91718.1 - 2.4e-06 27.3 0.0 4.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91718.1 - 3.1e-06 27.7 0.0 2.6e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91718.1 - 1.8e-05 25.2 0.0 8e-05 23.1 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG91718.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG91718.1 - 0.92 9.7 4.0 0.88 9.8 2.0 2.0 2 0 0 2 2 2 0 Zinc knuckle RVP_2 PF08284.11 GBG91719.1 - 1.5e-09 37.8 0.0 3.7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91719.1 - 2.4e-08 34.5 0.0 5.9e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91719.1 - 6.9e-07 29.7 0.0 1.7e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG91719.1 - 1.4e-06 28.0 0.1 2.5e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG91719.1 - 0.003 17.3 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease WD40 PF00400.32 GBG91720.1 - 3.1e-08 34.1 1.3 8e-05 23.3 0.1 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 GBG91720.1 - 0.0038 16.0 0.0 2.1 6.9 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GBG91720.1 - 0.004 17.4 0.3 0.55 10.6 0.0 3.0 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3137 PF11335.8 GBG91720.1 - 0.1 12.6 0.0 15 5.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) TGT_C1 PF14809.6 GBG91721.1 - 0.042 14.2 1.5 0.14 12.5 0.4 2.4 2 0 0 2 2 2 0 C1 domain of tRNA-guanine transglycosylase dimerisation FUSC PF04632.12 GBG91721.1 - 1.2 7.6 5.2 2.2 6.7 5.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_C48 PF02902.19 GBG91723.1 - 2.2e-05 24.4 0.0 3.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FMO-like PF00743.19 GBG91724.1 - 3e-17 62.3 0.0 1.1e-06 27.4 0.0 3.3 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GBG91724.1 - 3.7e-07 30.3 0.0 1.2e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GBG91724.1 - 4.8e-07 29.3 0.0 0.013 14.8 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GBG91724.1 - 0.00045 19.6 0.0 0.85 8.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GBG91724.1 - 0.0013 18.0 0.2 0.0032 16.8 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 GBG91724.1 - 0.0015 18.5 0.2 0.012 15.7 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 GBG91724.1 - 0.0023 16.7 0.3 0.004 15.9 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 GBG91724.1 - 0.003 18.1 0.6 0.031 14.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GBG91724.1 - 0.016 14.4 0.1 0.059 12.6 0.1 1.9 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 GBG91724.1 - 0.025 13.9 0.2 0.045 13.0 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GBG91724.1 - 0.029 14.2 0.4 0.051 13.5 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DHO_dh PF01180.21 GBG91727.1 - 2.2e-92 309.4 0.0 2.5e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 GBG91727.1 - 0.0005 19.5 0.0 0.0005 19.5 0.0 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 GBG91727.1 - 0.12 11.4 0.1 0.37 9.8 0.1 1.7 2 1 0 2 2 2 0 FMN-dependent dehydrogenase RT_RNaseH_2 PF17919.1 GBG91728.1 - 4.1e-27 94.1 0.0 8.3e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91728.1 - 3.4e-24 85.1 0.0 7.7e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91728.1 - 2.2e-10 40.4 0.0 3.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG91728.1 - 0.00013 22.4 0.0 0.00031 21.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG91728.1 - 0.0032 17.2 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91728.1 - 0.0035 17.9 0.0 0.012 16.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG91728.1 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Cwf_Cwc_15 PF04889.12 GBG91728.1 - 5 6.8 8.2 8.1 6.1 8.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG91728.1 - 6.9 4.8 6.7 10 4.3 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG91729.1 - 3.5e-10 39.8 0.0 7.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91729.1 - 1.7e-05 25.4 0.2 3.5e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91729.1 - 0.00048 20.6 0.1 0.0011 19.5 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-FCS PF06467.14 GBG91729.1 - 0.15 12.0 0.6 0.41 10.6 0.6 1.7 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CCHC PF00098.23 GBG91729.1 - 1.3 9.2 3.4 3.3 7.9 3.4 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG91730.1 - 1.5e-29 103.1 0.0 2.2e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hormone_3 PF00159.18 GBG91730.1 - 5.2 7.2 7.2 0.34 11.0 0.8 2.5 2 0 0 2 2 2 0 Pancreatic hormone peptide YL1 PF05764.13 GBG91731.1 - 0.0019 18.4 23.1 0.0019 18.4 23.1 2.2 2 0 0 2 2 2 1 YL1 nuclear protein Peptidase_M16_C PF05193.21 GBG91731.1 - 0.0026 17.8 0.0 0.0026 17.8 0.0 2.4 2 0 0 2 2 1 1 Peptidase M16 inactive domain AAA_23 PF13476.6 GBG91731.1 - 0.0046 17.5 12.4 0.0046 17.5 12.4 2.0 2 0 0 2 2 2 1 AAA domain RR_TM4-6 PF06459.12 GBG91731.1 - 0.0048 16.8 20.8 0.0048 16.8 20.8 1.7 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 GBG91731.1 - 0.0075 16.2 18.8 0.0075 16.2 18.8 2.1 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal GAGA_bind PF06217.12 GBG91731.1 - 0.091 13.0 20.4 0.017 15.4 13.0 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family DDHD PF02862.17 GBG91731.1 - 0.48 10.5 9.7 0.16 12.1 6.1 2.0 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.16 GBG91731.1 - 0.51 10.4 5.4 0.16 12.0 2.6 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Red1 PF07964.11 GBG91731.1 - 0.66 8.1 24.5 1.2 7.3 24.5 1.3 1 0 0 1 1 1 0 Rec10 / Red1 DUF4604 PF15377.6 GBG91731.1 - 1.1 9.6 38.1 0.019 15.4 28.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF913 PF06025.12 GBG91731.1 - 1.4 7.8 9.3 2.2 7.2 9.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2052 PF09747.9 GBG91731.1 - 1.6 8.8 19.5 0.32 11.1 14.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AAA_11 PF13086.6 GBG91731.1 - 1.6 8.4 17.4 0.26 11.1 12.2 2.0 2 0 0 2 2 2 0 AAA domain CLN3 PF02487.17 GBG91731.1 - 1.8 7.5 9.2 2.9 6.8 9.2 1.2 1 0 0 1 1 1 0 CLN3 protein BSMAP PF12280.8 GBG91731.1 - 1.9 8.7 5.9 4.7 7.4 5.9 1.7 1 0 0 1 1 1 0 Brain specific membrane anchored protein CobT PF06213.12 GBG91731.1 - 1.9 7.8 13.2 3.4 7.0 13.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF5308 PF17233.2 GBG91731.1 - 2 8.6 5.6 0.59 10.3 2.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5308) RNA_pol_Rpc4 PF05132.14 GBG91731.1 - 2.7 8.4 27.4 0.065 13.7 20.6 1.7 2 0 0 2 2 1 0 RNA polymerase III RPC4 V_ATPase_I PF01496.19 GBG91731.1 - 4.1 5.2 15.3 6.2 4.6 15.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SpoIIP PF07454.11 GBG91731.1 - 4.1 6.8 20.7 8.2 5.8 20.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Membralin PF09746.9 GBG91731.1 - 4.7 6.1 6.5 8.3 5.3 6.5 1.4 1 0 0 1 1 1 0 Tumour-associated protein NARP1 PF12569.8 GBG91731.1 - 7 5.4 34.5 3.7 6.3 30.1 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Peptidase_C37 PF05416.12 GBG91731.1 - 7.5 4.9 16.5 4.9 5.5 9.2 2.3 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Oleosin PF01277.17 GBG91732.1 - 1.9e-08 34.1 11.6 1.9e-08 34.1 11.6 2.5 2 1 0 2 2 2 1 Oleosin ABC2_membrane_3 PF12698.7 GBG91732.1 - 0.0004 19.6 4.9 0.00065 18.9 4.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein LEA_4 PF02987.16 GBG91732.1 - 0.052 13.6 4.1 0.1 12.7 4.1 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF2207 PF09972.9 GBG91732.1 - 0.12 11.1 2.7 0.35 9.6 2.6 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FtsX PF02687.21 GBG91732.1 - 6.8 7.2 12.0 13 6.3 12.1 1.4 1 1 0 1 1 1 0 FtsX-like permease family Aconitase PF00330.20 GBG91734.1 - 1.4e-79 268.3 0.0 3.1e-77 260.5 0.0 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) SAC3_GANP PF03399.16 GBG91736.1 - 3.4e-19 69.3 2.8 3.4e-19 69.3 2.8 3.5 3 1 0 3 3 3 1 SAC3/GANP family PRP38_assoc PF12871.7 GBG91736.1 - 0.0056 17.3 41.0 0.0056 17.3 41.0 4.5 4 2 1 5 5 5 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Mem_trans PF03547.18 GBG91736.1 - 0.32 9.4 0.8 0.36 9.2 0.0 1.5 2 0 0 2 2 2 0 Membrane transport protein Pkinase_Tyr PF07714.17 GBG91737.1 - 4.3e-46 157.3 0.0 2.8e-30 105.5 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG91737.1 - 3.5e-34 118.4 0.2 1.8e-26 93.1 0.0 2.7 2 1 1 3 3 3 2 Protein kinase domain PB1 PF00564.24 GBG91737.1 - 2.3e-13 49.9 0.1 4.3e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Pkinase_Tyr PF07714.17 GBG91738.1 - 4e-46 157.4 0.0 2.6e-30 105.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG91738.1 - 3.2e-34 118.5 0.2 1.7e-26 93.2 0.0 2.7 2 1 1 3 3 3 2 Protein kinase domain PB1 PF00564.24 GBG91738.1 - 2.2e-13 49.9 0.1 4.1e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Pkinase_Tyr PF07714.17 GBG91739.1 - 5.4e-43 147.1 0.0 9.1e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG91739.1 - 4.4e-35 121.3 0.0 8.3e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PB1 PF00564.24 GBG91739.1 - 7.9e-14 51.4 0.0 2.2e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 PB1 domain NDUF_B5 PF09781.9 GBG91739.1 - 0.24 10.9 0.5 0.63 9.6 0.5 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit zf-CCHC PF00098.23 GBG91740.1 - 0.054 13.6 0.9 0.054 13.6 0.9 2.1 2 0 0 2 2 2 0 Zinc knuckle GTP_EFTU PF00009.27 GBG91742.1 - 1.5e-52 178.0 0.0 2.4e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GBG91742.1 - 1.3e-17 63.5 0.0 4.1e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GBG91742.1 - 5.6e-07 29.6 0.4 3e-06 27.2 0.0 2.3 3 0 0 3 3 3 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 GBG91742.1 - 6.6e-07 29.6 0.0 3e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 GBG91742.1 - 0.0019 17.9 0.0 0.0075 16.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV RT_RNaseH_2 PF17919.1 GBG91744.1 - 6.8e-27 93.4 0.0 1.2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91744.1 - 8.6e-22 77.4 0.0 1.6e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91744.1 - 1.1e-10 41.5 0.1 1.6e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG91744.1 - 0.54 8.4 8.1 0.69 8.1 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG91744.1 - 0.68 9.3 9.5 1 8.7 9.5 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GBG91744.1 - 1.6 8.4 8.3 2.6 7.7 8.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG91744.1 - 1.7 6.8 9.1 2.4 6.4 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG91745.1 - 1.8e-27 96.3 0.0 2.4e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG91745.1 - 0.029 13.5 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Myb_DNA-bind_4 PF13837.6 GBG91746.1 - 1.6e-07 31.6 0.9 1.6e-06 28.4 0.6 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Nop14 PF04147.12 GBG91746.1 - 0.055 11.7 26.0 0.081 11.1 26.0 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG91746.1 - 0.12 10.4 29.1 0.22 9.6 29.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi RR_TM4-6 PF06459.12 GBG91746.1 - 0.27 11.1 12.9 0.42 10.4 12.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 GBG91746.1 - 0.28 10.7 16.8 0.54 9.8 16.8 1.6 1 0 0 1 1 1 0 PPP4R2 Mpp10 PF04006.12 GBG91746.1 - 0.33 9.3 25.3 0.53 8.7 25.3 1.2 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 GBG91746.1 - 0.46 8.7 21.0 0.72 8.1 21.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 GBG91746.1 - 1.6 8.5 12.9 3.7 7.3 12.9 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTPRCAP PF15713.5 GBG91746.1 - 2.1 8.6 25.3 0.56 10.5 21.3 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Vfa1 PF08432.10 GBG91746.1 - 2.2 8.6 10.9 4.9 7.4 10.9 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 GBG91746.1 - 4.5 7.2 13.0 10 6.0 13.0 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Merozoite_SPAM PF07133.11 GBG91746.1 - 5.9 6.8 33.7 14 5.6 33.7 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RVT_1 PF00078.27 GBG91747.1 - 1.8e-16 60.4 0.6 5.3e-10 39.2 0.0 2.5 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91747.1 - 6.1e-13 48.7 0.0 1.2e-11 44.5 0.0 2.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG91747.1 - 0.00043 20.5 1.1 0.0025 18.1 0.1 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH PF17917.1 GBG91747.1 - 0.00064 20.0 0.0 0.0051 17.1 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Vps62 PF06101.11 GBG91749.1 - 2e-23 82.5 0.0 4.8e-16 58.2 0.0 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 62 Toxin_10 PF05431.11 GBG91749.1 - 1.1e-06 28.3 0.2 1.7e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 Insecticidal Crystal Toxin, P42 Myb_DNA-bind_4 PF13837.6 GBG91750.1 - 1.9e-07 31.3 3.5 2.9e-07 30.8 1.3 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91750.1 - 0.00026 21.2 2.2 0.0055 17.0 0.7 2.7 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG91750.1 - 0.024 14.7 1.0 0.065 13.3 1.0 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Defensin_big PF14862.6 GBG91750.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Big defensin DDE_Tnp_4 PF13359.6 GBG91751.1 - 4.3e-26 91.5 0.0 6.6e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91751.1 - 1e-10 41.6 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG91751.1 - 0.051 13.2 1.7 0.079 12.6 0.0 2.2 3 0 0 3 3 3 0 Transposase DDE domain Vps62 PF06101.11 GBG91752.1 - 4.5e-29 101.2 0.0 9.4e-17 60.5 0.0 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 Toxin_10 PF05431.11 GBG91752.1 - 1.6e-07 31.0 0.1 3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Insecticidal Crystal Toxin, P42 Vps62 PF06101.11 GBG91753.1 - 6e-16 57.9 0.0 7.8e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DUF659 PF04937.15 GBG91754.1 - 2.6e-08 33.9 0.0 4.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Pkinase_Tyr PF07714.17 GBG91757.1 - 9.9e-36 123.3 0.0 2.4e-35 122.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG91757.1 - 3.8e-35 121.5 0.0 5.8e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG91757.1 - 1.4e-25 89.2 0.0 3.2e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91757.1 - 7.4e-24 84.1 0.0 1.9e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG91757.1 - 5.9 5.1 9.1 8.7 4.5 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Topo_Zn_Ribbon PF08272.11 GBG91760.1 - 0.02 14.5 0.3 0.047 13.3 0.3 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG91760.1 - 0.036 14.1 2.3 0.057 13.5 2.3 1.3 1 0 0 1 1 1 0 Zinc knuckle MBOAT_2 PF13813.6 GBG91763.1 - 1.4e-05 25.3 1.4 5.4e-05 23.4 0.1 2.4 2 1 1 3 3 3 1 Membrane bound O-acyl transferase family Plasmodium_Vir PF05795.11 GBG91763.1 - 0.062 12.7 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MBOAT_2 PF13813.6 GBG91765.1 - 1.1e-10 41.7 2.8 2.7e-05 24.4 0.4 2.8 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family Y_phosphatase PF00102.27 GBG91766.1 - 3.5e-54 183.9 0.0 1.4e-28 100.1 0.0 3.0 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GBG91766.1 - 7.9e-05 22.7 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GBG91766.1 - 0.061 13.1 0.1 0.18 11.6 0.1 1.8 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Malate_synthase PF01274.22 GBG91766.1 - 0.17 10.1 0.2 0.35 9.1 0.0 1.4 2 0 0 2 2 2 0 Malate synthase SOG2 PF10428.9 GBG91766.1 - 5.5 6.1 8.3 9.1 5.4 8.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF659 PF04937.15 GBG91767.1 - 1.7e-12 47.4 0.0 4.1e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DUF659 PF04937.15 GBG91768.1 - 2.3e-25 89.2 0.0 4.2e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91768.1 - 1.4e-06 28.0 0.7 4.5e-06 26.4 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-CCHC PF00098.23 GBG91768.1 - 0.00033 20.6 2.3 0.00071 19.5 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Mo-co_dimer PF03404.16 GBG91768.1 - 0.44 10.6 6.1 0.38 10.8 0.1 3.0 3 0 0 3 3 3 0 Mo-co oxidoreductase dimerisation domain Y_phosphatase PF00102.27 GBG91770.1 - 2.6e-51 174.5 0.4 5.9e-26 91.5 0.0 3.7 4 0 0 4 4 4 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GBG91770.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 GBG91770.1 - 0.39 10.5 0.8 1.3 8.9 0.5 2.0 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain RT_RNaseH_2 PF17919.1 GBG91771.1 - 1.2e-49 166.4 0.0 1.3e-24 86.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91771.1 - 3.3e-49 165.5 0.3 3.3e-24 85.2 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91771.1 - 1.7e-29 102.9 0.1 5.4e-28 98.0 0.0 2.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91771.1 - 2.3e-28 98.1 0.2 4.8e-15 55.4 0.1 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain Integrin_b_cyt PF08725.11 GBG91771.1 - 0.0029 17.3 0.2 3.2 7.5 0.0 2.5 2 0 0 2 2 2 2 Integrin beta cytoplasmic domain Nif11 PF07862.11 GBG91771.1 - 0.047 14.0 0.0 1.5 9.2 0.0 3.0 2 0 0 2 2 2 0 Nif11 domain rve PF00665.26 GBG91771.1 - 0.081 13.1 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain AbrB_C PF18277.1 GBG91771.1 - 0.12 12.1 0.0 17 5.1 0.0 2.4 2 0 0 2 2 2 0 AbrB C-terminal domain HTH_54 PF18607.1 GBG91771.1 - 0.16 12.1 0.0 19 5.4 0.0 2.6 2 0 0 2 2 2 0 ParA helix turn helix domain P4Ha_N PF08336.11 GBG91771.1 - 0.2 11.7 0.4 7 6.7 0.1 2.6 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Matrilin_ccoil PF10393.9 GBG91771.1 - 0.73 9.7 2.8 0.77 9.7 1.3 1.8 2 0 0 2 2 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Lzipper-MIP1 PF14389.6 GBG91771.1 - 1.7 9.0 4.0 0.79 10.1 0.1 2.4 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 SlyX PF04102.12 GBG91771.1 - 9.5 6.9 6.8 5 7.8 0.3 3.2 3 0 0 3 3 3 0 SlyX A_thal_3526 PF09713.10 GBG91774.1 - 5.9e-25 87.3 0.5 8.6e-25 86.8 0.5 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) Peptidase_M41 PF01434.18 GBG91775.1 - 0.00078 19.3 1.1 0.0085 16.0 0.3 2.5 2 1 0 2 2 2 1 Peptidase family M41 UL45 PF05473.12 GBG91776.1 - 0.0055 16.4 0.0 0.0059 16.3 0.0 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like CTD PF12815.7 GBG91777.1 - 0.019 15.5 4.2 0.044 14.3 4.0 1.9 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 HC2 PF07382.11 GBG91777.1 - 1.1 9.2 27.3 0.73 9.9 23.7 2.0 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 DUF5384 PF17358.2 GBG91780.1 - 0.15 12.1 5.7 0.26 11.3 5.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5384) zf-BED PF02892.15 GBG91781.1 - 0.002 18.1 0.1 0.0055 16.7 0.1 1.7 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_4 PF13894.6 GBG91781.1 - 0.14 13.1 0.3 0.63 11.0 0.3 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger UCH PF00443.29 GBG91782.1 - 2.1e-39 135.6 0.0 2.7e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GBG91782.1 - 6.1e-14 52.1 1.8 1.3e-13 51.1 1.8 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 GBG91782.1 - 0.5 10.2 4.6 0.26 11.1 1.5 2.0 2 0 0 2 2 2 0 Variant UBP zinc finger RVT_1 PF00078.27 GBG91783.1 - 1.7e-29 102.9 0.0 3.7e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91783.1 - 8.2e-27 93.2 0.0 3.3e-26 91.2 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91783.1 - 9.5e-15 54.8 0.1 3.3e-14 53.0 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG91783.1 - 3e-07 30.6 2.0 0.15 12.4 0.0 4.3 3 0 0 3 3 3 2 Retrotransposon gag protein DUF4939 PF16297.5 GBG91783.1 - 2.7e-05 24.0 0.0 0.45 10.4 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4939) Phycobilisome PF00502.19 GBG91783.1 - 0.02 14.8 3.6 51 3.7 0.0 4.6 4 0 0 4 4 4 0 Phycobilisome protein Arm PF00514.23 GBG91783.1 - 0.12 12.4 1.0 34 4.6 0.1 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ToxS PF17323.2 GBG91783.1 - 0.44 10.2 2.1 22 4.7 0.2 2.4 2 0 0 2 2 2 0 Trans-membrane regulatory protein ToxS DNA_pack_N PF02500.15 GBG91783.1 - 0.48 10.2 2.2 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Snapin_Pallidin PF14712.6 GBG91783.1 - 0.76 10.2 14.3 4.6 7.7 0.1 4.2 3 0 0 3 3 3 0 Snapin/Pallidin SpoIIIAH PF12685.7 GBG91784.1 - 0.099 12.5 2.7 0.11 12.3 2.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein OAD_gamma PF04277.13 GBG91784.1 - 1.2 9.8 3.8 1.9 9.1 3.8 1.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AP3D1 PF06375.11 GBG91784.1 - 2 8.6 19.4 3.2 8.0 19.4 1.4 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 Med19 PF10278.9 GBG91784.1 - 7.2 6.5 15.8 11 5.9 15.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SDA1 PF05285.12 GBG91785.1 - 1.2 8.4 38.4 1.7 8.0 38.4 1.1 1 0 0 1 1 1 0 SDA1 Oleosin PF01277.17 GBG91786.1 - 4e-05 23.3 35.9 0.0045 16.7 5.5 3.8 3 1 0 3 3 3 2 Oleosin PrgI PF12666.7 GBG91786.1 - 0.039 14.7 4.7 0.039 14.7 4.7 2.8 2 1 0 2 2 2 0 PrgI family protein DUF2207 PF09972.9 GBG91786.1 - 1.5 7.5 7.6 1.7 7.3 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RT_RNaseH PF17917.1 GBG91787.1 - 3.6e-23 81.9 0.0 7.8e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91787.1 - 6.3e-22 77.5 0.0 1.3e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91787.1 - 2e-12 47.0 0.6 4.7e-12 45.8 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG91787.1 - 6.9e-11 42.1 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG91787.1 - 3.1e-10 40.3 0.0 9.2e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG91787.1 - 8.9e-07 29.4 0.0 2.8e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91787.1 - 0.0011 19.6 0.0 0.0028 18.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG91787.1 - 0.0015 18.3 0.3 0.0043 16.8 0.3 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG91787.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease MIS13 PF08202.11 GBG91787.1 - 0.18 11.0 1.0 0.4 9.9 1.0 1.5 1 0 0 1 1 1 0 Mis12-Mtw1 protein family EMP24_GP25L PF01105.24 GBG91788.1 - 1.3e-53 181.6 0.5 2.8e-53 180.6 0.0 1.6 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 GBG91788.1 - 0.0033 17.6 0.1 0.0046 17.2 0.1 1.2 1 0 0 1 1 1 1 SdrD B-like domain COX8 PF02285.15 GBG91788.1 - 0.015 15.2 0.3 0.015 15.2 0.3 1.6 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII RlmM_FDX PF18125.1 GBG91788.1 - 0.047 14.2 0.0 0.09 13.3 0.0 1.4 1 0 0 1 1 1 0 RlmM ferredoxin-like domain Hum_adeno_E3A PF05393.11 GBG91788.1 - 0.14 12.2 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF4235 PF14019.6 GBG91789.1 - 0.11 12.6 1.5 0.27 11.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) 5-FTHF_cyc-lig PF01812.20 GBG91790.1 - 3.1e-38 131.5 0.0 4.4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.22 GBG91790.1 - 4.9e-07 29.5 0.0 8.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Inhibitor_Mig-6 PF11555.8 GBG91792.1 - 1.7 8.8 6.1 4.7 7.4 6.1 1.7 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 RVT_1 PF00078.27 GBG91793.1 - 5.6e-12 45.7 0.0 8.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG91794.1 - 0.0009 17.6 42.6 0.0012 17.2 42.6 1.2 1 0 0 1 1 1 1 Nop14-like family DEPP PF15343.6 GBG91796.1 - 3.9e-07 30.3 1.6 0.024 14.7 0.2 2.4 2 0 0 2 2 2 2 Decidual protein induced by progesterone family RVT_1 PF00078.27 GBG91796.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3545 PF12065.8 GBG91796.1 - 2.1 8.4 8.7 16 5.6 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Exo_endo_phos PF03372.23 GBG91797.1 - 2e-06 27.5 0.0 4.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 GBG91797.1 - 0.00037 20.1 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GBG91797.1 - 0.00093 19.9 5.9 0.00093 19.9 5.9 3.3 4 0 0 4 4 4 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 GBG91797.1 - 0.0016 18.2 0.0 0.005 16.7 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Integrase_H2C2 PF17921.1 GBG91798.1 - 4.4e-07 29.9 1.5 6.4e-07 29.4 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG91799.1 - 8.5e-07 29.2 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG91800.1 - 0.00087 19.5 2.0 0.0022 18.3 0.2 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG91800.1 - 0.00092 18.9 0.8 0.0025 17.6 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) SR-25 PF10500.9 GBG91801.1 - 1 8.9 28.1 0.059 13.0 22.7 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 GBG91801.1 - 7.5 4.7 11.3 13 3.9 11.3 1.3 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH PF17917.1 GBG91803.1 - 5e-27 94.2 0.0 1.1e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91803.1 - 2.2e-26 92.8 0.0 4.7e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91803.1 - 3.4e-22 78.4 0.0 4.4e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91803.1 - 1.9e-13 50.3 0.1 8.6e-13 48.2 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG91803.1 - 1.2e-08 35.1 0.3 9e-08 32.3 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG91803.1 - 0.0022 18.2 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG91803.1 - 0.039 14.6 0.0 0.11 13.2 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease Virulence_RhuM PF13310.6 GBG91804.1 - 0.026 13.8 0.1 0.038 13.2 0.1 1.3 1 0 0 1 1 1 0 Virulence protein RhuM family DUF4611 PF15387.6 GBG91804.1 - 1.2 9.4 7.0 0.62 10.3 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAM76 PF16046.5 GBG91805.1 - 0.013 14.9 9.4 0.015 14.7 9.4 1.1 1 0 0 1 1 1 0 FAM76 protein PspB PF06667.12 GBG91805.1 - 0.56 10.3 9.6 9 6.4 0.2 3.3 3 1 0 3 3 3 0 Phage shock protein B DUF4666 PF15697.5 GBG91805.1 - 2.7 8.7 7.3 1.7 9.4 4.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) APG6_N PF17675.1 GBG91805.1 - 2.9 8.4 26.6 0.93 10.0 2.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Presenilin PF01080.17 GBG91805.1 - 6.6 5.4 6.2 7 5.3 6.2 1.2 1 0 0 1 1 1 0 Presenilin AAA_12 PF13087.6 GBG91806.1 - 2.7e-55 187.1 0.0 5.9e-55 186.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RT_RNaseH_2 PF17919.1 GBG91806.1 - 1.4e-30 105.3 0.0 5e-30 103.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91806.1 - 1.8e-19 70.0 0.0 4.9e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Viral_helicase1 PF01443.18 GBG91806.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase gpUL132 PF11359.8 GBG91806.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 RVT_1 PF00078.27 GBG91806.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) UvrD_C_2 PF13538.6 GBG91806.1 - 0.16 11.9 0.0 0.49 10.3 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Pkinase PF00069.25 GBG91807.1 - 1.1e-18 67.6 0.1 3.3e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91807.1 - 1.2e-14 54.3 0.0 2.9e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GBG91807.1 - 4.2e-11 43.2 8.4 1.6e-06 28.7 0.6 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4670 PF15709.5 GBG91807.1 - 6 6.1 16.3 8.2 5.6 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Pkinase PF00069.25 GBG91808.1 - 2.4e-18 66.5 0.0 4e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG91808.1 - 8e-16 58.1 0.0 1.3e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HALZ PF02183.18 GBG91810.1 - 8.3 6.7 17.7 19 5.5 0.2 5.6 5 1 0 5 5 5 0 Homeobox associated leucine zipper Ribosomal_60s PF00428.19 GBG91811.1 - 3.3e-21 75.6 10.7 5.6e-21 74.9 10.7 1.3 1 1 0 1 1 1 1 60s Acidic ribosomal protein TTc_toxin_rep PF18807.1 GBG91812.1 - 0.29 11.0 1.3 28 4.6 0.0 2.7 3 0 0 3 3 3 0 Tripartite Tc toxins repeat Myb_DNA-bind_4 PF13837.6 GBG91813.1 - 2.7e-10 40.5 1.3 1e-08 35.4 0.3 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain COG5 PF10392.9 GBG91815.1 - 5.4e-27 94.6 2.8 5.4e-27 94.6 2.8 3.1 4 0 0 4 4 4 1 Golgi transport complex subunit 5 COG2 PF06148.11 GBG91815.1 - 8.1e-06 26.0 1.2 8.1e-06 26.0 1.2 2.5 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 GBG91815.1 - 0.0004 20.3 2.6 0.041 13.8 0.3 3.2 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 GBG91815.1 - 0.03 13.6 7.9 0.015 14.6 3.4 2.3 2 1 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 GBG91815.1 - 0.036 12.6 1.1 0.069 11.7 1.1 1.5 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Vps51 PF08700.11 GBG91815.1 - 0.071 13.2 0.6 0.28 11.3 0.1 2.4 2 0 0 2 2 2 0 Vps51/Vps67 Sec5 PF15469.6 GBG91815.1 - 0.13 12.1 2.3 42 3.9 0.1 4.0 4 1 0 4 4 4 0 Exocyst complex component Sec5 Spc7 PF08317.11 GBG91815.1 - 0.56 9.0 7.3 0.053 12.4 2.0 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein MnmE_helical PF12631.7 GBG91815.1 - 1 9.5 8.0 0.14 12.3 1.5 2.6 3 1 0 3 3 3 0 MnmE helical domain Fez1 PF06818.15 GBG91815.1 - 6.3 7.2 6.6 5.5 7.4 3.2 2.3 2 0 0 2 2 2 0 Fez1 Chlorophyllase2 PF12740.7 GBG91816.1 - 7.5e-10 38.1 0.3 0.0034 16.3 0.0 3.3 2 1 1 3 3 3 3 Chlorophyllase enzyme Chlorophyllase PF07224.11 GBG91816.1 - 1e-09 37.9 0.4 0.0091 15.0 0.0 3.2 2 1 1 3 3 3 3 Chlorophyllase Myb_DNA-bind_4 PF13837.6 GBG91816.1 - 2.7e-08 34.1 0.4 4.8e-08 33.3 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PAF-AH_p_II PF03403.13 GBG91816.1 - 0.00059 18.5 0.5 0.0061 15.1 0.1 2.0 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Myb_DNA-bind_5 PF13873.6 GBG91816.1 - 0.007 16.4 0.7 0.014 15.5 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 GBG91817.1 - 2.2e-26 92.8 0.1 3.4e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91817.1 - 7e-18 64.5 0.0 2.8e-17 62.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91817.1 - 2.9e-06 27.5 0.0 8.1e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DDHD PF02862.17 GBG91817.1 - 0.37 10.9 3.0 0.66 10.1 3.0 1.4 1 0 0 1 1 1 0 DDHD domain TFIIF_alpha PF05793.12 GBG91817.1 - 1 7.8 27.0 1.4 7.4 27.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 GBG91817.1 - 1.3 8.3 31.6 1.9 7.8 31.6 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG91817.1 - 1.9 7.8 34.8 3 7.1 34.8 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GBG91817.1 - 3 6.0 23.1 4.5 5.4 23.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG91817.1 - 5.5 5.1 34.2 8.5 4.5 34.2 1.2 1 0 0 1 1 1 0 Nop14-like family Plasmodium_Vir PF05795.11 GBG91817.1 - 8.4 5.7 8.9 13 5.1 8.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Dimer_Tnp_hAT PF05699.14 GBG91818.1 - 9.4e-09 35.0 0.1 1.6e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Spc7 PF08317.11 GBG91820.1 - 0.046 12.6 112.9 0.047 12.6 22.2 5.4 1 1 4 5 5 5 0 Spc7 kinetochore protein HTH_54 PF18607.1 GBG91820.1 - 0.079 13.0 0.2 0.079 13.0 0.2 4.2 4 1 0 4 4 4 0 ParA helix turn helix domain RT_RNaseH_2 PF17919.1 GBG91821.1 - 5.5e-19 68.1 0.0 1.9e-18 66.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91821.1 - 3.7e-09 36.8 0.0 1.4e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91821.1 - 1.4e-08 34.6 0.0 2.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PA26 PF04636.13 GBG91821.1 - 0.17 10.7 9.0 0.23 10.3 9.0 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Radial_spoke_3 PF06098.11 GBG91821.1 - 5.2 6.2 20.3 11 5.2 20.3 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 zf-RanBP PF00641.18 GBG91822.1 - 6.3e-22 76.6 25.9 2.3e-08 33.2 2.9 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others zf-RRN7 PF11781.8 GBG91822.1 - 8.7e-05 22.1 3.1 1.3 8.7 0.0 3.8 3 0 0 3 3 3 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PHD PF00628.29 GBG91822.1 - 0.0015 18.4 2.3 14 5.7 0.1 3.4 3 0 0 3 3 3 0 PHD-finger PsaX PF08078.12 GBG91822.1 - 0.0017 18.3 0.3 5.6 7.0 0.0 3.2 3 0 0 3 3 3 1 PsaX family Prim_Zn_Ribbon PF08273.12 GBG91822.1 - 0.0042 17.3 9.4 1.4 9.3 0.8 3.8 3 0 0 3 3 3 1 Zinc-binding domain of primase-helicase DUF3725 PF12523.8 GBG91822.1 - 0.0053 17.0 3.3 0.49 10.7 0.2 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3725) TF_Zn_Ribbon PF08271.12 GBG91822.1 - 0.0091 15.5 8.6 4.4 6.9 1.5 3.6 4 0 0 4 4 3 1 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 GBG91822.1 - 0.015 15.0 1.4 16 5.3 0.0 3.5 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Sec23_Sec24 PF04810.15 GBG91822.1 - 0.016 15.2 5.1 8.6 6.5 0.0 3.7 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Zf_RING PF16744.5 GBG91822.1 - 0.22 11.6 3.2 36 4.6 0.1 3.2 3 0 0 3 3 3 0 KIAA1045 RING finger Rubredoxin PF00301.20 GBG91822.1 - 0.35 10.9 9.3 0.47 10.5 0.4 3.6 3 0 0 3 3 3 0 Rubredoxin zf-4CXXC_R1 PF10497.9 GBG91822.1 - 0.42 10.8 15.4 3.5 7.9 0.7 2.5 2 1 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 TackOD1 PF18551.1 GBG91822.1 - 0.52 10.0 11.9 0.73 9.5 0.1 3.0 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 RNA_POL_M_15KD PF02150.16 GBG91822.1 - 0.69 9.8 20.1 0.68 9.9 1.0 4.4 4 1 0 4 4 4 0 RNA polymerases M/15 Kd subunit zf-ACC PF17848.1 GBG91822.1 - 1 9.5 11.9 1.7 8.8 0.1 3.8 4 0 0 4 4 3 0 Acetyl-coA carboxylase zinc finger domain Rubredoxin_2 PF18073.1 GBG91822.1 - 2.1 8.2 17.0 5.4 6.8 0.3 4.3 5 0 0 5 5 5 0 Rubredoxin metal binding domain zf-C4pol PF14260.6 GBG91822.1 - 2.7 8.5 9.4 16 6.0 0.2 3.1 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta C1_2 PF03107.16 GBG91822.1 - 2.9 8.3 12.2 27 5.2 0.7 3.2 3 0 0 3 3 3 0 C1 domain DUF4379 PF14311.6 GBG91822.1 - 3.6 8.0 10.5 19 5.7 0.1 3.3 3 0 0 3 3 3 0 Probable Zinc-ribbon domain DUF35_N PF12172.8 GBG91822.1 - 7.3 6.6 20.1 0.57 10.1 3.2 3.5 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_ribbon_SprT PF17283.2 GBG91822.1 - 9.5 6.2 9.9 6.8 6.7 0.2 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-C2H2_3 PF13878.6 GBG91823.1 - 1.3e-13 50.6 0.3 4.1e-13 48.9 0.3 2.0 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_13 PF13880.6 GBG91823.1 - 8.1e-08 32.1 1.3 1.7e-07 31.1 1.3 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 GBG91823.1 - 0.075 13.5 0.0 0.38 11.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DSPc PF00782.20 GBG91824.1 - 2.9e-25 88.6 0.0 4.4e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 GBG91824.1 - 1.6e-06 27.9 0.0 0.028 14.3 0.0 3.3 2 1 0 2 2 2 2 Gelsolin repeat Y_phosphatase PF00102.27 GBG91824.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LEA_6 PF10714.9 GBG91824.1 - 1.7 8.7 4.5 1.3 9.1 1.8 2.2 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 RT_RNaseH_2 PF17919.1 GBG91825.1 - 5.5e-24 84.1 0.0 9.4e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91825.1 - 8.4e-24 83.9 0.0 1.6e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91825.1 - 4.8e-11 42.6 0.1 8.4e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG91825.1 - 0.04 12.2 4.5 0.05 11.8 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 GBG91825.1 - 0.14 12.4 10.1 0.3 11.4 10.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG91825.1 - 0.4 8.9 8.7 0.58 8.4 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG91825.1 - 2 7.8 10.7 2.9 7.2 10.7 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GBG91825.1 - 4.2 5.4 9.9 6.2 4.8 9.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop53 PF07767.11 GBG91825.1 - 6.1 6.1 12.0 9.6 5.5 12.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) zf-CCHC PF00098.23 GBG91826.1 - 5.8e-06 26.1 1.8 1.2e-05 25.1 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG91826.1 - 0.013 15.3 1.3 0.019 14.8 0.5 1.7 2 0 0 2 2 2 0 Zinc knuckle RPOL_N PF14700.6 GBG91826.1 - 0.08 12.3 8.4 0.14 11.5 8.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal zf-CCHC_3 PF13917.6 GBG91826.1 - 1.3 9.0 4.1 0.57 10.2 0.9 2.0 2 0 0 2 2 2 0 Zinc knuckle Mitofilin PF09731.9 GBG91826.1 - 1.5 7.6 26.5 0.34 9.7 23.0 1.6 1 1 1 2 2 2 0 Mitochondrial inner membrane protein DUF4407 PF14362.6 GBG91826.1 - 4 6.7 9.4 7.5 5.8 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 GBG91827.1 - 2.4e-25 89.4 0.1 3.3e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91827.1 - 3.3e-06 27.7 0.0 6.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91827.1 - 2.6e-05 24.7 0.0 4.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG91827.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG91827.1 - 0.024 14.4 0.0 0.058 13.2 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG91828.1 - 1.1e-05 25.2 2.6 1.1e-05 25.2 2.6 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG91828.1 - 0.031 14.0 2.1 0.12 12.1 2.1 2.0 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RVT_1 PF00078.27 GBG91828.1 - 0.051 13.1 0.0 2.1 7.8 0.0 2.4 1 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tae4 PF14113.6 GBG91828.1 - 3.4 7.9 6.7 1.7 8.9 0.0 3.4 3 0 0 3 3 3 0 Type VI secretion system (T6SS), amidase effector protein 4 DUF4366 PF14283.6 GBG91829.1 - 0.48 10.5 7.1 0.038 14.0 1.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) SLC12 PF03522.15 GBG91829.1 - 1.9 7.4 5.8 2 7.3 5.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 YabA PF06156.13 GBG91830.1 - 0.36 11.5 13.7 6.1 7.5 2.9 4.0 4 0 0 4 4 4 0 Initiation control protein YabA Flagellin_N PF00669.20 GBG91830.1 - 2.4 8.2 6.3 24 5.0 3.8 2.4 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region RVT_1 PF00078.27 GBG91831.1 - 1.4e-24 86.9 0.0 2.1e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRN3 PF05327.11 GBG91833.1 - 0.0015 17.2 16.5 0.0024 16.5 16.5 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 EutK_C PF16365.5 GBG91833.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus DNA_pol_phi PF04931.13 GBG91833.1 - 0.31 9.1 40.9 0.48 8.5 40.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG91833.1 - 3.1 5.9 28.7 4.9 5.2 28.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG91833.1 - 6.1 5.0 25.4 11 4.2 25.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 GBG91833.1 - 7.5 5.2 7.0 3.5 6.3 0.8 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DDE_Tnp_4 PF13359.6 GBG91834.1 - 5e-28 97.7 0.0 8.8e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91834.1 - 2.2e-14 53.5 0.0 3.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Angiomotin_C PF12240.8 GBG91835.1 - 0.0045 16.6 0.7 0.014 15.0 0.7 1.8 1 0 0 1 1 1 1 Angiomotin C terminal GrpE PF01025.19 GBG91835.1 - 0.027 14.1 0.8 0.067 12.8 0.8 1.6 1 0 0 1 1 1 0 GrpE Spectrin PF00435.21 GBG91836.1 - 0.075 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Spectrin repeat zf-RING_2 PF13639.6 GBG91837.1 - 1.2e-07 31.9 10.5 2.2e-07 31.1 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GBG91837.1 - 0.0001 21.9 10.2 0.0002 21.0 10.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GBG91837.1 - 0.00045 20.4 7.1 0.0011 19.2 7.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain ISG65-75 PF11727.8 GBG91837.1 - 0.004 16.4 7.3 0.004 16.4 7.3 2.9 3 0 0 3 3 3 1 Invariant surface glycoprotein zf-C3HC4_2 PF13923.6 GBG91837.1 - 0.0073 16.1 11.6 0.013 15.3 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG91837.1 - 0.012 15.6 10.0 0.021 14.8 10.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 GBG91837.1 - 0.055 13.4 10.4 0.093 12.6 10.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GBG91837.1 - 0.085 12.7 9.4 0.14 12.0 9.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Reprolysin_3 PF13582.6 GBG91837.1 - 0.17 12.4 1.6 0.34 11.5 0.4 2.2 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like zf-ANAPC11 PF12861.7 GBG91837.1 - 0.7 10.0 5.6 1.5 8.9 5.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GBG91837.1 - 0.85 9.7 9.3 1.6 8.8 9.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger LMBR1 PF04791.16 GBG91838.1 - 3.5e-68 230.8 19.3 1.2e-43 149.9 3.9 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein CCSMST1 PF15013.6 GBG91838.1 - 0.087 13.0 0.2 0.087 13.0 0.2 4.0 4 1 1 5 5 5 0 CCSMST1 family DUF659 PF04937.15 GBG91840.1 - 0.00094 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4618 PF15397.6 GBG91842.1 - 0.0018 17.8 0.2 0.0036 16.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) HIP1_clath_bdg PF16515.5 GBG91842.1 - 0.018 15.7 3.5 0.018 15.7 3.5 3.2 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 GBG91842.1 - 0.097 12.8 0.5 0.097 12.8 0.5 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 GBG91842.1 - 0.15 12.5 0.8 1.8 9.1 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SPARC_Ca_bdg PF10591.9 GBG91842.1 - 0.3 11.4 2.6 0.97 9.8 2.6 2.0 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Scaffolding_pro PF11418.8 GBG91842.1 - 2 9.0 4.9 14 6.3 0.1 2.7 3 0 0 3 3 3 0 Phi29 scaffolding protein BLOC1_2 PF10046.9 GBG91842.1 - 4.7 7.6 7.5 1 9.7 1.2 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myb_DNA-bind_4 PF13837.6 GBG91843.1 - 1.1e-08 35.3 2.9 2.2e-08 34.3 2.9 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91843.1 - 0.011 16.1 0.8 0.024 14.9 0.8 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LapA_dom PF06305.11 GBG91843.1 - 0.028 14.2 0.3 0.046 13.5 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MAP17 PF15807.5 GBG91843.1 - 0.15 12.3 0.1 0.39 10.9 0.1 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Myb_DNA-bind_5 PF13873.6 GBG91843.1 - 3.5 7.8 5.5 0.43 10.7 0.4 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Integrase_H2C2 PF17921.1 GBG91846.1 - 2.8e-14 52.9 2.8 4.8e-14 52.2 0.1 2.8 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG91846.1 - 5e-13 49.3 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91846.1 - 2.3e-05 24.5 0.0 5.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 GBG91846.1 - 0.025 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG91846.1 - 0.028 15.0 0.0 0.062 13.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Pectinesterase PF01095.19 GBG91847.1 - 7.4e-64 215.3 0.0 1e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 Pectinesterase SYS1 PF09801.9 GBG91849.1 - 1.9e-42 144.8 10.8 2.7e-42 144.3 10.8 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Methyltransf_12 PF08242.12 GBG91850.1 - 0.14 13.0 0.0 0.34 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Fes1 PF08609.10 GBG91850.1 - 2.4 9.1 4.9 19 6.2 2.5 2.4 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 RRM_1 PF00076.22 GBG91851.1 - 1.2e-85 281.4 5.7 1.8e-22 78.9 0.2 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GBG91851.1 - 1.6e-08 34.2 0.1 0.0049 16.5 0.0 3.9 2 1 2 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GBG91851.1 - 4.1e-08 33.3 0.0 1.5e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 GBG91851.1 - 1.8e-06 27.9 0.1 1.6 8.9 0.0 5.1 4 3 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GBG91851.1 - 0.00022 21.2 0.6 9.3 6.3 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.8 GBG91851.1 - 0.0074 16.4 0.0 4.2 7.6 0.0 2.6 2 1 0 2 2 2 1 Cobalamin biosynthesis central region SET_assoc PF11767.8 GBG91851.1 - 0.012 15.3 0.2 15 5.3 0.0 4.1 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated RRM_2 PF04059.12 GBG91851.1 - 0.027 14.7 0.6 0.31 11.3 0.2 2.8 4 0 0 4 4 4 0 RNA recognition motif 2 Cas_Cas2CT1978 PF09707.10 GBG91851.1 - 0.049 13.7 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) TC1 PF15063.6 GBG91851.1 - 0.051 13.5 0.0 1.5 8.8 0.0 2.9 2 0 0 2 2 2 0 Thyroid cancer protein 1 PHM7_cyt PF14703.6 GBG91851.1 - 0.051 13.8 0.3 27 4.9 0.0 3.7 2 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 GBG91851.1 - 0.094 12.4 3.7 11 5.8 0.1 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Ldh_1_C PF02866.18 GBG91852.1 - 8e-24 84.5 0.0 1.3e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GBG91852.1 - 3.9e-08 33.5 0.1 7e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain BTB PF00651.31 GBG91853.1 - 8.6e-12 45.3 0.1 2.8e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 GBG91854.1 - 9.7e-13 48.3 0.0 1.4e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GBG91856.1 - 3.7e-10 40.0 0.0 6.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Rieske PF00355.26 GBG91857.1 - 7.2e-18 64.3 0.0 7.9e-17 61.0 0.0 2.2 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 GBG91857.1 - 4.1e-09 36.5 0.0 9.6e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Pheophorbide a oxygenase SLX9 PF15341.6 GBG91858.1 - 0.014 15.8 2.5 0.031 14.7 2.5 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF3987 PF13148.6 GBG91858.1 - 0.44 9.5 5.9 0.6 9.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RRN3 PF05327.11 GBG91858.1 - 1.4 7.4 5.2 2 6.9 5.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RT_RNaseH_2 PF17919.1 GBG91862.1 - 5e-33 113.1 0.0 7.7e-33 112.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91862.1 - 4.2e-23 81.6 0.0 8e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91862.1 - 2.5e-18 66.4 0.0 3.6e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5095 PF17016.5 GBG91862.1 - 0.15 11.8 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) eIF2A PF08662.11 GBG91863.1 - 4.6e-73 245.2 0.0 7.9e-73 244.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 GBG91863.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain WD40 PF00400.32 GBG91863.1 - 0.16 12.9 4.2 64 4.7 0.0 5.5 6 1 1 7 7 7 0 WD domain, G-beta repeat CHD5 PF04420.14 GBG91864.1 - 0.15 11.9 2.7 0.29 11.0 2.7 1.4 1 0 0 1 1 1 0 CHD5-like protein ACC_epsilon PF13822.6 GBG91864.1 - 0.62 10.8 3.2 0.69 10.6 0.4 2.6 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit BAF1_ABF1 PF04684.13 GBG91864.1 - 3.8 6.5 7.1 5.8 5.8 7.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF659 PF04937.15 GBG91866.1 - 1e-16 61.2 0.0 1.5e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG91867.1 - 2.2e-31 109.1 0.1 3.4e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91867.1 - 1.8e-23 82.5 0.0 3.2e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91867.1 - 3.3e-22 78.8 0.0 6e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91867.1 - 1.4e-16 60.3 1.8 6.1e-16 58.3 0.2 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG91867.1 - 4.4e-05 23.6 0.0 8.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91867.1 - 0.00038 20.6 0.2 0.00099 19.3 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG91868.1 - 0.00042 20.5 4.2 0.0011 19.1 0.0 3.0 2 1 1 3 3 3 1 Retrotransposon gag protein SbmA_BacA PF05992.12 GBG91869.1 - 0.037 13.5 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 SbmA/BacA-like family Nup54 PF13874.6 GBG91870.1 - 0.28 11.3 1.7 0.56 10.3 1.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RT_RNaseH_2 PF17919.1 GBG91872.1 - 2.8e-31 107.5 0.0 1.2e-15 57.4 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91872.1 - 4.1e-31 107.4 0.0 8.2e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91872.1 - 4.3e-31 108.2 0.0 6.7e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91872.1 - 2.5e-14 53.1 0.2 8.7e-14 51.4 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG91872.1 - 1.6e-05 25.1 0.0 5.3e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger SDA1 PF05285.12 GBG91874.1 - 1.3 8.4 18.8 1.7 8.0 18.8 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 GBG91874.1 - 5.9 6.5 10.4 8.3 6.0 10.4 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 GBG91874.1 - 8.2 4.6 17.2 11 4.2 17.2 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC PF00098.23 GBG91875.1 - 0.0001 22.2 4.1 0.00016 21.6 4.1 1.3 1 0 0 1 1 1 1 Zinc knuckle AAA_23 PF13476.6 GBG91875.1 - 0.0013 19.2 8.6 0.0018 18.8 8.6 1.2 1 0 0 1 1 1 1 AAA domain zf-CCHC_3 PF13917.6 GBG91875.1 - 0.0018 18.2 0.7 0.0047 16.9 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG91875.1 - 0.014 15.1 1.0 0.025 14.3 1.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger UPF0242 PF06785.11 GBG91875.1 - 0.023 14.8 8.0 0.034 14.2 8.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 GBG91875.1 - 0.026 13.2 9.3 0.031 12.9 9.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-CCHC_4 PF14392.6 GBG91875.1 - 0.17 11.7 0.5 0.35 10.6 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG91875.1 - 0.52 10.2 2.0 1.2 9.1 2.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4407 PF14362.6 GBG91875.1 - 1.1 8.6 9.1 1.7 7.9 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 GBG91875.1 - 1.1 10.1 19.2 2.3 9.1 19.2 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain AAA_11 PF13086.6 GBG91875.1 - 1.2 8.8 11.0 1.8 8.3 11.0 1.2 1 0 0 1 1 1 0 AAA domain KIP1 PF07765.12 GBG91875.1 - 2.9 8.1 9.3 2 8.6 5.3 2.3 1 1 1 2 2 2 0 KIP1-like protein Tho2 PF11262.8 GBG91875.1 - 3 7.0 11.8 4.2 6.5 11.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 V_ATPase_I PF01496.19 GBG91875.1 - 3.4 5.5 7.5 4.1 5.2 7.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 GBG91875.1 - 3.9 6.2 8.9 4.7 5.9 8.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4337 PF14235.6 GBG91875.1 - 4.2 7.5 7.7 6 7.0 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) NAC PF01849.18 GBG91876.1 - 2.9e-21 75.2 0.1 6e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 NAC domain DHR10 PF18595.1 GBG91877.1 - 0.083 12.9 0.7 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Abhydrolase_1 PF00561.20 GBG91878.1 - 7e-27 94.7 0.0 1.4e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG91878.1 - 5.7e-18 65.1 0.0 7.5e-17 61.4 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG91878.1 - 3.8e-14 53.8 0.5 3.8e-14 53.8 0.5 1.9 3 0 0 3 3 2 1 Alpha/beta hydrolase family Esterase PF00756.20 GBG91878.1 - 0.00023 20.9 0.1 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 Putative esterase Ser_hydrolase PF06821.13 GBG91878.1 - 0.0021 17.9 0.0 0.0064 16.4 0.0 1.8 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.14 GBG91878.1 - 0.0041 15.9 0.0 0.0074 15.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF2920 PF11144.8 GBG91878.1 - 0.0049 16.1 0.0 2.1 7.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2920) Thioesterase PF00975.20 GBG91878.1 - 0.018 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 GBG91878.1 - 0.022 14.1 0.0 0.05 12.9 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 GBG91878.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 GBG91878.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 GBG91878.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 GBG91879.1 - 5.4e-27 95.1 0.0 9.5e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GBG91879.1 - 3.7e-18 65.7 0.0 5.1e-17 61.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GBG91879.1 - 2.6e-14 54.4 0.5 2.6e-14 54.4 0.5 1.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family Esterase PF00756.20 GBG91879.1 - 0.00017 21.3 0.1 0.0009 19.0 0.0 2.2 3 0 0 3 3 3 1 Putative esterase Ser_hydrolase PF06821.13 GBG91879.1 - 0.0017 18.2 0.0 0.0052 16.7 0.0 1.8 1 0 0 1 1 1 1 Serine hydrolase DUF2920 PF11144.8 GBG91879.1 - 0.0033 16.7 0.0 1.7 7.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2920) Ndr PF03096.14 GBG91879.1 - 0.0033 16.2 0.0 0.006 15.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 GBG91879.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 GBG91879.1 - 0.017 14.4 0.0 0.041 13.2 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 GBG91879.1 - 0.062 13.0 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 GBG91879.1 - 0.089 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 GBG91879.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Myb_DNA-bind_4 PF13837.6 GBG91880.1 - 7e-09 35.9 2.0 1.6e-08 34.8 2.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG91880.1 - 5.4e-05 23.3 4.9 0.0018 18.4 0.6 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91880.1 - 0.0088 16.3 0.9 0.018 15.3 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG91880.1 - 0.1 12.7 0.8 0.2 11.8 0.8 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG91881.1 - 1.2e-22 80.2 0.2 4e-22 78.6 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG91881.1 - 8.6e-12 45.1 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG91881.1 - 0.023 15.1 0.1 0.073 13.5 0.1 1.9 1 0 0 1 1 1 0 Transposase DDE domain SdpA PF17418.2 GBG91882.1 - 0.2 11.5 1.0 5 7.0 0.0 2.5 2 0 0 2 2 2 0 Sporulation delaying protein SdpA LMWPc PF01451.21 GBG91883.1 - 9.1e-16 58.5 0.0 1e-15 58.4 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MarR_2 PF12802.7 GBG91883.1 - 0.071 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 MarR family RVT_1 PF00078.27 GBG91884.1 - 7e-29 100.9 0.0 1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L34 PF00468.17 GBG91884.1 - 0.17 11.9 0.0 16 5.6 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L34 Integrase_H2C2 PF17921.1 GBG91885.1 - 2.3e-09 37.2 0.0 6.5e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG91885.1 - 4.4e-08 32.9 0.0 7.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG91885.1 - 1.3e-06 28.8 0.0 3.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91885.1 - 0.00019 22.0 0.0 0.0004 21.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG91885.1 - 0.015 15.4 2.0 0.041 14.0 2.0 1.8 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.20 GBG91885.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease F-box-like PF12937.7 GBG91886.1 - 4.8e-09 36.0 0.3 9.1e-09 35.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GBG91886.1 - 2.2e-06 27.4 0.3 5.3e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 GBG91886.1 - 0.034 14.6 0.6 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box_5 PF18511.1 GBG91886.1 - 0.04 13.5 0.5 0.074 12.6 0.5 1.4 1 0 0 1 1 1 0 F-box Cys_Met_Meta_PP PF01053.20 GBG91888.1 - 2.6e-129 431.1 0.0 3e-129 430.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GBG91888.1 - 8.2e-08 31.6 0.2 1.2e-07 31.1 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GBG91888.1 - 3.4e-06 26.6 0.3 6.6e-06 25.6 0.3 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GBG91888.1 - 8.7e-06 25.3 3.0 9.2e-06 25.2 1.8 1.6 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 GBG91888.1 - 2.8e-05 23.5 0.0 3.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 GBG91888.1 - 0.0012 17.5 0.0 0.002 16.7 0.0 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GBG91888.1 - 0.0019 17.1 0.1 0.0026 16.6 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein HCV_NS4a PF01006.20 GBG91888.1 - 0.79 9.5 2.6 1.9 8.3 0.1 2.7 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a DUF898 PF05987.13 GBG91889.1 - 0.013 14.6 0.4 0.013 14.6 0.4 4.3 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF898) BDV_G PF06208.11 GBG91889.1 - 0.046 12.9 6.6 7.8 5.5 0.0 5.0 5 2 2 7 7 7 0 Borna disease virus G protein MIG-14_Wnt-bd PF06664.12 GBG91889.1 - 8.7 5.5 21.4 0.095 11.9 0.4 3.1 2 1 1 3 3 3 0 Wnt-binding factor required for Wnt secretion RT_RNaseH_2 PF17919.1 GBG91890.1 - 1.2e-31 108.7 0.1 6.1e-30 103.2 0.0 4.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91890.1 - 1.1e-30 106.0 1.3 6.7e-30 103.5 0.0 3.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase KRTAP PF11759.8 GBG91890.1 - 2.5e-08 34.3 15.9 0.88 10.2 0.0 9.9 5 4 0 5 5 5 2 Keratin-associated matrix Integrase_H2C2 PF17921.1 GBG91890.1 - 0.00044 20.3 0.0 0.00074 19.6 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain HEAT PF02985.22 GBG91891.1 - 4.7e-08 32.6 23.5 0.33 11.3 0.1 11.1 12 0 0 12 12 12 3 HEAT repeat Cnd1 PF12717.7 GBG91891.1 - 1.2e-05 25.4 1.7 0.005 16.9 0.0 4.7 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 GBG91891.1 - 1.6 8.9 4.0 32 4.8 0.0 4.6 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 GBG91891.1 - 4.4 7.7 8.1 10 6.5 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion RVT_1 PF00078.27 GBG91892.1 - 3.2e-11 43.2 0.2 6e-11 42.3 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91892.1 - 3.4e-10 39.9 0.0 6.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91892.1 - 0.016 15.5 0.0 0.51 10.7 0.0 2.6 1 1 1 2 2 2 0 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG91892.1 - 5.4 5.2 10.2 7.5 4.7 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein gag-asp_proteas PF13975.6 GBG91896.1 - 4.6e-07 30.3 0.0 1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91896.1 - 6.2e-05 23.6 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG91896.1 - 0.0048 16.7 0.1 0.0082 15.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG91896.1 - 0.041 13.7 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG91896.1 - 0.065 13.3 1.9 0.14 12.3 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG91896.1 - 0.15 11.7 0.3 0.47 10.2 0.3 1.8 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Pkinase_Tyr PF07714.17 GBG91897.1 - 9e-35 120.2 0.0 1.7e-34 119.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG91897.1 - 1.7e-31 109.6 0.0 2.5e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG91901.1 - 5e-29 100.3 0.0 1.1e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91901.1 - 2.7e-27 95.1 0.1 7.2e-27 93.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chlam_PMP PF02415.17 GBG91901.1 - 0.00013 22.2 10.4 2.6 8.7 0.0 5.4 5 0 0 5 5 5 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RVT_1 PF00078.27 GBG91901.1 - 0.0095 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C_GCAxxG_C_C PF09719.10 GBG91901.1 - 0.023 15.0 1.4 0.067 13.5 1.4 1.7 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) FAM60A PF15396.6 GBG91901.1 - 1.4 8.9 13.0 3.7 7.5 13.0 1.8 1 1 0 1 1 1 0 Protein Family FAM60A RVT_1 PF00078.27 GBG91902.1 - 1e-37 129.8 0.0 1.5e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91903.1 - 2e-20 72.7 0.2 6.1e-20 71.1 0.2 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91903.1 - 1.2e-10 41.6 0.1 2.6e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG91903.1 - 7.4e-09 35.8 0.0 2.2e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG91903.1 - 2.8e-07 30.3 0.1 4.2e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG91903.1 - 9.1e-07 28.9 0.0 9.1e-07 28.9 0.0 2.9 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG91903.1 - 8.1e-05 22.8 1.9 9.6e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger zf-4CXXC_R1 PF10497.9 GBG91903.1 - 0.0076 16.5 2.9 0.025 14.8 2.9 1.8 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Tubulin PF00091.25 GBG91904.1 - 2.8e-67 226.8 0.0 3.8e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GBG91904.1 - 6.4e-52 175.0 0.1 9.9e-52 174.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GBG91904.1 - 0.013 15.1 0.0 0.04 13.6 0.0 1.9 2 0 0 2 2 2 0 Tubulin domain DUF659 PF04937.15 GBG91907.1 - 6.3e-19 68.3 0.0 9.2e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG91908.1 - 7.8e-24 84.0 0.0 1.3e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91908.1 - 1.7e-22 79.4 0.0 3.4e-22 78.4 0.0 1.5 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Drf_GBD PF06371.13 GBG91908.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain RVT_1 PF00078.27 GBG91908.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91909.1 - 3.5e-23 81.9 0.0 7.4e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91909.1 - 6.8e-22 77.4 0.0 1.9e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CNRIP1 PF15043.6 GBG91909.1 - 0.024 14.2 3.1 4 7.0 0.2 2.5 2 0 0 2 2 2 0 CB1 cannabinoid receptor-interacting protein 1 OCRL_clath_bd PF16726.5 GBG91909.1 - 0.035 14.3 1.3 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Inositol polyphosphate 5-phosphatase clathrin binding domain Drf_GBD PF06371.13 GBG91909.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.2 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain UPF0561 PF10573.9 GBG91909.1 - 0.66 10.1 7.3 10 6.2 0.8 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 DUF4449 PF14613.6 GBG91909.1 - 4.7 7.3 11.3 14 5.7 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Gag_p17 PF00540.18 GBG91909.1 - 6 6.8 6.1 36 4.3 0.6 2.7 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) RVT_1 PF00078.27 GBG91910.1 - 1.4e-15 57.5 0.0 2.4e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lin-8 PF03353.15 GBG91911.1 - 0.03 13.9 5.0 0.038 13.5 5.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 GBG91911.1 - 0.059 12.8 5.7 0.066 12.6 5.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG91911.1 - 0.15 10.3 6.3 0.15 10.3 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG91911.1 - 0.46 8.7 7.9 0.53 8.5 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NPV_P10 PF05531.12 GBG91912.1 - 0.075 13.5 3.9 0.67 10.5 4.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 GBG91912.1 - 0.22 11.5 11.5 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding MRP-S31 PF15433.6 GBG91912.1 - 0.88 9.2 13.1 1 9.0 13.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF4407 PF14362.6 GBG91912.1 - 5.8 6.2 22.6 17 4.7 22.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CsgE PF10627.9 GBG91912.1 - 6.9 6.9 8.9 4 7.7 6.5 2.0 2 1 0 2 2 2 0 Curli assembly protein CsgE Presenilin PF01080.17 GBG91912.1 - 7.1 5.3 9.1 8.1 5.1 9.1 1.2 1 0 0 1 1 1 0 Presenilin FAM76 PF16046.5 GBG91912.1 - 8.5 5.6 9.8 12 5.1 9.8 1.2 1 0 0 1 1 1 0 FAM76 protein Topo_Zn_Ribbon PF08272.11 GBG91914.1 - 0.077 12.7 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG91914.1 - 0.14 12.3 2.1 0.22 11.6 2.1 1.3 1 0 0 1 1 1 0 Zinc knuckle PFOR_II PF17147.4 GBG91915.1 - 0.18 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II CwfJ_C_1 PF04677.15 GBG91917.1 - 7.3e-19 67.8 0.2 9.3e-17 61.0 0.0 2.3 1 1 1 2 2 2 2 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 GBG91917.1 - 2.2e-13 50.9 0.1 6.1e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf_CCCH_4 PF18345.1 GBG91917.1 - 3.8e-10 39.5 26.4 0.00011 22.2 5.0 3.6 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 GBG91917.1 - 8e-09 36.2 13.3 0.0035 18.0 2.2 3.7 1 1 2 3 3 3 3 Torus domain zf-CCCH PF00642.24 GBG91917.1 - 3.5e-06 26.8 21.9 0.0024 17.7 1.7 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GBG91917.1 - 0.0029 17.4 20.9 0.0056 16.4 3.6 3.6 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 GBG91917.1 - 0.45 10.8 8.2 0.74 10.1 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger containing family AAA_12 PF13087.6 GBG91919.1 - 3.6e-36 124.7 0.0 6.4e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GBG91919.1 - 8.1e-26 91.4 1.0 9.2e-12 45.3 0.6 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GBG91919.1 - 5.7e-09 36.4 0.0 9.1e-07 29.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GBG91919.1 - 1.1e-08 35.0 1.6 4.5e-05 23.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.9 GBG91919.1 - 0.00036 19.9 0.2 0.072 12.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 GBG91919.1 - 0.026 14.0 0.2 0.078 12.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Enolase_N PF03952.16 GBG91919.1 - 0.033 14.4 0.5 0.087 13.0 0.5 1.6 1 0 0 1 1 1 0 Enolase, N-terminal domain ResIII PF04851.15 GBG91919.1 - 0.083 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GBG91919.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Cupin_1 PF00190.22 GBG91920.1 - 2e-38 131.3 0.0 1.1e-22 80.3 0.0 2.7 3 0 0 3 3 3 2 Cupin PDT PF00800.18 GBG91921.1 - 7.8e-56 188.8 0.0 1.1e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 GBG91921.1 - 6.8e-06 25.8 0.0 2.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 ACT domain PDT PF00800.18 GBG91923.1 - 8.6e-55 185.4 0.0 1.4e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase RT_RNaseH PF17917.1 GBG91923.1 - 2.3e-22 79.3 0.0 3.9e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91923.1 - 2.1e-18 66.2 0.0 3.9e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ACT PF01842.25 GBG91923.1 - 2.3e-05 24.1 0.0 6.3e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 ACT domain UTP25 PF06862.12 GBG91924.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PDT PF00800.18 GBG91925.1 - 5.8e-58 195.7 0.0 8.2e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 GBG91925.1 - 2.8e-06 27.0 0.0 1.1e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 ACT domain zf-CCHC_6 PF15288.6 GBG91926.1 - 0.00083 19.1 0.4 0.0043 16.9 0.4 2.2 1 0 0 1 1 1 1 Zinc knuckle Glycos_transf_1 PF00534.20 GBG91926.1 - 0.14 11.6 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 RVT_1 PF00078.27 GBG91927.1 - 6.1e-26 91.3 0.0 2e-25 89.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91927.1 - 3.6e-24 84.7 0.0 1.7e-23 82.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91927.1 - 1e-14 54.7 0.0 5.6e-14 52.3 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG91927.1 - 1.1e-06 29.1 0.0 2.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91927.1 - 1.6e-06 28.6 0.0 3.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG91927.1 - 2e-06 27.6 0.0 4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG91927.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease HIP1_clath_bdg PF16515.5 GBG91927.1 - 0.0081 16.7 2.4 0.0081 16.7 2.4 2.3 3 0 0 3 3 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Laminin_II PF06009.12 GBG91927.1 - 0.17 11.9 0.2 0.57 10.2 0.2 1.9 1 1 0 1 1 1 0 Laminin Domain II FlxA PF14282.6 GBG91927.1 - 0.23 11.5 2.8 18 5.4 1.3 2.5 2 0 0 2 2 2 0 FlxA-like protein DivIC PF04977.15 GBG91927.1 - 2 8.2 3.9 4.9 7.0 1.4 2.6 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 GBG91927.1 - 2 9.1 5.5 6.9 7.4 1.2 3.5 3 0 0 3 3 3 0 SlyX LPP PF04728.13 GBG91927.1 - 3.6 8.1 4.7 10 6.6 0.2 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper TMF_TATA_bd PF12325.8 GBG91927.1 - 7.8 6.8 6.9 1.9 8.7 0.4 2.7 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding RT_RNaseH_2 PF17919.1 GBG91928.1 - 2.4e-33 114.2 0.0 5.4e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91928.1 - 6.2e-30 103.6 0.1 1.4e-29 102.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91928.1 - 7.8e-18 64.3 0.3 1.7e-17 63.3 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91928.1 - 1.1e-14 54.7 0.0 3e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91928.1 - 0.0002 21.5 0.0 0.00051 20.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Tmemb_cc2 PF10267.9 GBG91928.1 - 0.011 15.0 3.0 0.023 13.9 3.0 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FAM199X PF15814.5 GBG91928.1 - 9.6 5.2 7.9 25 3.8 7.9 1.7 1 0 0 1 1 1 0 Protein family FAM199X FokI_N PF02981.15 GBG91929.1 - 0.056 13.6 0.9 2 8.6 0.4 2.3 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain DUF4139 PF13598.6 GBG91929.1 - 0.2 11.4 5.5 1.3 8.7 4.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4139) Cytadhesin_P30 PF07271.11 GBG91929.1 - 2.4 7.7 7.3 4.6 6.7 7.3 1.5 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF3500 PF12006.8 GBG91929.1 - 5.9 6.3 6.9 4.1 6.8 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3500) PCEMA1 PF07418.11 GBG91930.1 - 0.42 10.1 16.3 0.53 9.8 16.3 1.0 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 PIEZO PF15917.5 GBG91930.1 - 3.4 7.1 14.2 4 6.9 14.2 1.2 1 0 0 1 1 1 0 Piezo Mem_trans PF03547.18 GBG91932.1 - 0.083 11.3 0.1 0.13 10.6 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF659 PF04937.15 GBG91933.1 - 3.6e-31 108.1 0.0 6.1e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) gag-asp_proteas PF13975.6 GBG91934.1 - 9e-05 23.0 0.1 0.00038 20.9 0.1 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91934.1 - 0.0002 21.9 0.1 0.00057 20.5 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_4 PF14392.6 GBG91934.1 - 2.8 7.8 7.3 6.7 6.5 7.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Dimer_Tnp_hAT PF05699.14 GBG91935.1 - 0.006 16.3 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RT_RNaseH PF17917.1 GBG91936.1 - 5.7e-24 84.4 0.0 1.6e-23 83.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91936.1 - 1.8e-22 79.2 0.0 4.4e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91936.1 - 3.1e-09 36.7 0.0 5.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG91938.1 - 1.5e-16 60.7 0.1 3e-16 59.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91938.1 - 4e-07 29.7 0.2 2.3e-06 27.3 0.1 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Clat_adaptor_s PF01217.20 GBG91939.1 - 9.3e-24 84.0 0.4 1.1e-23 83.7 0.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TDP43_N PF18694.1 GBG91939.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain RT_RNaseH PF17917.1 GBG91940.1 - 2.5e-22 79.2 0.0 5.7e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91940.1 - 4.8e-22 77.9 0.0 9.1e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91940.1 - 4.8e-09 36.1 0.0 8.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAS_3 PF08447.12 GBG91940.1 - 0.14 12.4 0.2 15 5.9 0.0 2.9 2 0 0 2 2 2 0 PAS fold Integrase_H2C2 PF17921.1 GBG91941.1 - 2.9e-17 62.5 0.3 7.1e-17 61.3 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91941.1 - 2.9e-08 33.9 0.0 8.1e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG91941.1 - 7.7e-06 26.1 0.4 1.6e-05 25.1 0.4 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG91941.1 - 0.032 14.1 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Na_H_Exchanger PF00999.21 GBG91942.1 - 6e-39 133.9 42.3 8.8e-39 133.4 42.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 GBG91942.1 - 0.0001 22.8 0.2 0.014 15.9 0.0 3.2 2 1 0 2 2 2 1 Universal stress protein family Acylphosphatase PF00708.18 GBG91943.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase Presenilin PF01080.17 GBG91943.1 - 7 5.3 13.3 8.8 5.0 13.3 1.1 1 0 0 1 1 1 0 Presenilin 4HBT PF03061.22 GBG91944.1 - 7.8e-10 39.0 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily RVP_2 PF08284.11 GBG91945.1 - 0.00024 20.9 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91945.1 - 0.0064 17.1 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ADP_ribosyl_GH PF03747.14 GBG91945.1 - 0.01 15.6 0.2 0.54 9.9 0.3 2.3 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase RVP_2 PF08284.11 GBG91946.1 - 2.4e-07 30.6 0.0 6.9e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1664 PF07889.12 GBG91946.1 - 0.00052 20.0 3.1 0.00073 19.6 1.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 GBG91946.1 - 0.00082 19.4 1.7 0.0023 18.0 1.7 1.8 1 0 0 1 1 1 1 TolA binding protein trimerisation gag-asp_proteas PF13975.6 GBG91946.1 - 0.0022 18.5 0.0 0.006 17.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91946.1 - 0.0023 18.5 0.0 0.0083 16.7 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG91946.1 - 0.0024 18.1 1.5 0.021 15.1 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein APG17 PF04108.12 GBG91946.1 - 0.031 13.4 0.5 0.062 12.4 0.1 1.6 2 0 0 2 2 2 0 Autophagy protein Apg17 Jnk-SapK_ap_N PF09744.9 GBG91946.1 - 0.066 13.4 1.1 0.13 12.5 1.1 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TRPM_tetra PF16519.5 GBG91946.1 - 0.14 12.3 0.5 38 4.5 0.0 3.2 3 0 0 3 3 3 0 Tetramerisation domain of TRPM Asp_protease PF09668.10 GBG91946.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Trimer_CC PF08954.11 GBG91946.1 - 9.9 5.8 8.3 0.42 10.2 1.2 2.5 2 1 0 2 2 2 0 Trimerisation motif CooT PF10133.9 GBG91947.1 - 0.029 14.6 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT Rxt3 PF08642.10 GBG91947.1 - 0.52 11.1 4.5 0.25 12.1 1.4 2.0 1 1 1 2 2 2 0 Histone deacetylation protein Rxt3 RVT_1 PF00078.27 GBG91948.1 - 9.9e-30 103.7 0.1 1.3e-29 103.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTRD1 PF17660.1 GBG91948.1 - 0.12 12.2 0.0 4.1 7.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 Actin PF00022.19 GBG91949.1 - 4.8e-22 78.1 0.0 5.3e-13 48.4 0.0 3.1 1 1 1 2 2 2 2 Actin CCDC24 PF15669.5 GBG91949.1 - 0.12 12.3 0.3 0.19 11.6 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Exonuc_VII_L PF02601.15 GBG91950.1 - 0.031 13.9 5.5 0.049 13.2 5.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 GBG91950.1 - 0.69 10.0 17.6 0.8 9.8 16.7 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Myb_DNA-bind_4 PF13837.6 GBG91951.1 - 1.4e-08 35.0 3.9 2.1e-08 34.4 2.0 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG91951.1 - 0.13 12.6 2.4 0.18 12.1 0.5 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Nop53 PF07767.11 GBG91951.1 - 0.75 9.1 7.3 0.74 9.1 5.4 1.8 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) zf-CCHC PF00098.23 GBG91952.1 - 6e-05 22.9 2.3 0.00013 21.8 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG91952.1 - 0.023 14.5 6.5 0.024 14.5 4.5 2.0 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG91953.1 - 1e-25 89.7 0.0 3.2e-25 88.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91953.1 - 9.4e-24 83.7 0.0 2.8e-23 82.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG91953.1 - 5.3e-07 30.2 0.0 1.3e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 GBG91953.1 - 3.1e-06 27.2 0.1 6.7e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG91953.1 - 5.6e-06 26.2 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG91953.1 - 3.5e-05 24.3 0.0 0.00011 22.7 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 GBG91953.1 - 0.00035 20.2 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG91953.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Senescence_reg PF04520.13 GBG91953.1 - 0.25 12.2 2.0 0.58 11.0 2.0 1.6 1 0 0 1 1 1 0 Senescence regulator DUF4366 PF14283.6 GBG91954.1 - 0.055 13.5 2.1 0.086 12.9 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 GBG91954.1 - 0.063 12.0 7.6 0.074 11.8 7.6 1.0 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 GBG91954.1 - 0.14 11.6 3.2 0.18 11.2 3.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 GBG91954.1 - 0.22 11.3 12.9 0.29 10.9 12.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RT_RNaseH_2 PF17919.1 GBG91956.1 - 1e-32 112.1 0.1 4.4e-32 110.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91956.1 - 1.1e-30 106.9 0.0 2.1e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91956.1 - 4.9e-26 91.1 0.4 2.6e-25 88.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91956.1 - 3.6e-19 68.6 0.2 7.8e-19 67.5 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91956.1 - 4e-16 59.3 0.0 1.4e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG91956.1 - 5.3e-05 23.7 0.0 0.00023 21.7 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG91956.1 - 0.00012 22.6 0.0 0.00028 21.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG91956.1 - 0.0003 20.9 0.2 0.0015 18.7 0.0 2.4 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease PF09668.10 GBG91956.1 - 0.086 12.6 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease DUF1758 PF05585.12 GBG91956.1 - 0.12 12.1 0.1 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative peptidase (DUF1758) TMEM117 PF15113.6 GBG91957.1 - 0.025 13.5 0.1 0.034 13.1 0.1 1.2 1 0 0 1 1 1 0 TMEM117 protein family EOS1 PF12326.8 GBG91957.1 - 0.26 11.2 4.3 0.08 12.9 1.6 1.4 2 0 0 2 2 2 0 N-glycosylation protein Phage_TAC_4 PF08748.11 GBG91958.1 - 1.6 9.1 5.8 1.8 8.9 4.1 2.1 2 1 0 2 2 2 0 Phage tail assembly chaperone EF-hand_5 PF13202.6 GBG91961.1 - 0.00071 19.0 0.0 0.0047 16.4 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 GBG91961.1 - 0.0024 17.3 0.0 0.031 13.8 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GBG91961.1 - 0.055 13.4 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 GBG91961.1 - 0.072 13.6 0.0 0.58 10.7 0.0 2.6 1 0 0 1 1 1 0 EF-hand domain pair Presenilin PF01080.17 GBG91961.1 - 5.3 5.7 7.5 11 4.6 7.5 1.6 1 0 0 1 1 1 0 Presenilin Pyridoxal_deC PF00282.19 GBG91963.1 - 1.3e-92 310.4 0.2 1.3e-61 208.4 0.0 2.3 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain RVT_1 PF00078.27 GBG91963.1 - 1.7e-24 86.6 0.1 3.2e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91963.1 - 2.6e-24 85.1 0.0 6.7e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91963.1 - 2.6e-20 72.6 0.0 7.5e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG91963.1 - 6.1e-14 51.9 0.2 1.5e-13 50.6 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG91963.1 - 4.5e-06 26.5 0.0 9.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91963.1 - 9.2e-06 26.2 0.0 1.9e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG91963.1 - 1.3e-05 25.3 0.0 4.1e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG91963.1 - 8.1e-05 23.1 0.0 0.00019 21.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG91963.1 - 0.0046 16.8 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HIP1_clath_bdg PF16515.5 GBG91963.1 - 0.0096 16.5 2.0 0.0096 16.5 2.0 2.3 2 0 0 2 2 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Asp_protease PF09668.10 GBG91963.1 - 0.03 14.1 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 GBG91964.1 - 2.4e-16 59.6 0.3 9e-16 57.7 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG91964.1 - 5.6e-15 55.5 0.1 1.2e-14 54.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG91964.1 - 3.2e-10 40.3 0.1 1e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GBG91964.1 - 1.2e-08 34.7 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG91964.1 - 5.3e-07 29.6 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG91964.1 - 0.00021 21.4 0.0 0.00046 20.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger GMC_oxred_C PF05199.13 GBG91964.1 - 0.026 15.0 1.1 0.57 10.7 0.0 2.6 3 0 0 3 3 3 0 GMC oxidoreductase DUF4588 PF15251.6 GBG91964.1 - 0.14 11.9 0.4 0.22 11.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) RVT_1 PF00078.27 GBG91965.1 - 1.8e-27 96.3 0.0 2.6e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Apc13p PF05839.11 GBG91967.1 - 0.0012 19.0 0.3 0.0025 18.0 0.3 1.5 1 0 0 1 1 1 1 Apc13p protein FtsK_4TM PF13491.6 GBG91967.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE DUF659 PF04937.15 GBG91968.1 - 1.7e-29 102.7 0.1 2.2e-29 102.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) NIF PF03031.18 GBG91969.1 - 2.8e-15 56.4 0.0 3.8e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NTP_transferase PF00483.23 GBG91971.1 - 9.7e-12 45.0 0.0 2.3e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 GBG91971.1 - 2.3e-07 30.3 16.7 0.00054 19.6 4.1 4.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GBG91971.1 - 2.5e-06 27.9 0.1 4e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 GBG91971.1 - 7.9e-05 21.0 9.0 0.00018 19.8 9.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 GBG91971.1 - 0.00015 21.5 12.2 0.38 10.6 0.3 4.5 2 1 2 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 GBG91971.1 - 0.0091 15.0 6.7 0.024 13.6 1.2 2.2 1 1 1 2 2 2 2 L-fucokinase TTL PF03133.15 GBG91972.1 - 6.7e-95 317.6 0.0 9.9e-95 317.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GBG91972.1 - 6.8e-06 25.5 0.1 0.00018 20.9 0.0 2.6 4 0 0 4 4 4 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 GBG91972.1 - 0.0017 17.7 0.0 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Integrase_H2C2 PF17921.1 GBG91974.1 - 1.6e-18 66.6 0.3 3.1e-18 65.6 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91974.1 - 2.1e-14 53.7 0.1 4.4e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91974.1 - 8.8e-05 22.7 0.2 0.00039 20.6 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger UPF0242 PF06785.11 GBG91974.1 - 0.51 10.4 3.2 12 5.9 3.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CCD48 PF15799.5 GBG91976.1 - 0.0027 16.1 1.5 0.0035 15.7 1.5 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 bZIP_2 PF07716.15 GBG91976.1 - 0.048 13.7 2.9 0.048 13.7 2.9 1.8 2 0 0 2 2 2 0 Basic region leucine zipper CCDC85 PF10226.9 GBG91976.1 - 0.051 13.3 0.6 0.12 12.0 0.1 1.7 1 1 1 2 2 2 0 CCDC85 family bZIP_1 PF00170.21 GBG91976.1 - 0.1 12.7 1.1 0.2 11.8 1.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.18 GBG91976.1 - 0.17 12.2 1.6 0.32 11.2 1.6 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper GvpL_GvpF PF06386.11 GBG91976.1 - 1.2 9.0 5.6 1.8 8.4 5.6 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF RT_RNaseH_2 PF17919.1 GBG91977.1 - 4.9e-31 106.7 0.0 2.4e-30 104.5 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91977.1 - 4.7e-30 104.0 2.1 1.4e-29 102.4 0.0 2.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase MT PF12777.7 GBG91977.1 - 3e-26 92.3 6.3 3e-26 92.3 6.3 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Integrase_H2C2 PF17921.1 GBG91977.1 - 8.5e-20 70.6 0.5 1.9e-19 69.5 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91977.1 - 0.0002 21.5 0.1 0.00067 19.8 0.1 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG91977.1 - 0.00065 19.9 0.1 0.0021 18.3 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger IncFII_repA PF02387.15 GBG91977.1 - 0.099 11.9 3.7 0.22 10.7 3.7 1.5 1 0 0 1 1 1 0 IncFII RepA protein family Phage_GPO PF05929.11 GBG91977.1 - 0.27 10.8 0.0 0.27 10.8 0.0 3.9 4 0 0 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase Z1 PF10593.9 GBG91977.1 - 6.6 6.2 8.1 1.7 8.1 3.6 2.3 2 0 0 2 2 2 0 Z1 domain DUF659 PF04937.15 GBG91978.1 - 0.00028 20.8 0.0 0.00055 19.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) API5 PF05918.11 GBG91978.1 - 0.00073 18.5 3.0 0.0012 17.7 3.0 1.3 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) DUF29 PF01724.16 GBG91978.1 - 0.92 9.7 4.0 1.3 9.2 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF29 rve PF00665.26 GBG91979.1 - 2.1e-07 31.2 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG91980.1 - 1.1e-35 123.2 1.4 5.1e-22 78.5 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91980.1 - 2.3e-16 60.0 1.1 5.5e-16 58.8 1.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG91980.1 - 5.5e-09 36.0 2.2 1.1e-08 35.1 0.2 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG91980.1 - 3.1e-07 30.2 0.0 7.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG91980.1 - 7e-05 23.4 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG91980.1 - 0.0001 22.8 0.0 0.00031 21.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG91980.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Hemocyanin_N PF03722.14 GBG91980.1 - 0.15 12.6 1.6 0.59 10.7 0.2 2.5 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain RT_RNaseH_2 PF17919.1 GBG91981.1 - 2e-31 108.0 0.0 4.5e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91981.1 - 3.3e-29 102.0 0.1 5.5e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG91981.1 - 2.7e-27 95.1 0.0 5.3e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG91981.1 - 1.5e-05 24.8 3.8 3.9e-05 23.5 3.8 1.7 1 0 0 1 1 1 1 Zinc knuckle Shugoshin_N PF07558.11 GBG91981.1 - 0.099 12.5 2.8 3.4 7.6 0.1 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF3464 PF11947.8 GBG91981.1 - 0.11 12.2 2.7 0.24 11.1 2.7 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 zf-CCHC_3 PF13917.6 GBG91981.1 - 0.12 12.4 0.7 0.32 11.0 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG91981.1 - 1.1 9.2 5.0 2 8.3 5.0 1.5 1 0 0 1 1 1 0 Zinc knuckle BSP_II PF05432.11 GBG91982.1 - 0.25 11.0 40.6 0.32 10.6 40.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.6 GBG91982.1 - 0.68 10.3 8.7 26 5.3 0.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KH_5 PF13184.6 GBG91983.1 - 0.097 12.8 0.2 1.3 9.1 0.0 2.9 3 0 0 3 3 3 0 NusA-like KH domain KH_5 PF13184.6 GBG91984.1 - 0.094 12.8 0.2 1.3 9.1 0.0 2.9 3 0 0 3 3 3 0 NusA-like KH domain DUF2935 PF11155.8 GBG91984.1 - 7.2 7.0 9.1 1.4 9.3 0.4 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) TctB PF07331.11 GBG91987.1 - 0.16 12.3 9.4 0.9 9.8 0.9 2.4 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family LAP1C PF05609.12 GBG91987.1 - 1.4 8.0 7.8 3.6 6.6 7.8 1.6 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2345 PF10106.9 GBG91987.1 - 2.3 8.1 9.0 0.75 9.6 2.9 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) RVT_1 PF00078.27 GBG91988.1 - 1.2e-28 100.2 0.1 1.7e-28 99.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG91988.1 - 2.9e-20 72.2 0.0 1.9e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG91988.1 - 7.4e-12 45.0 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG91988.1 - 4.2e-09 36.6 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG91989.1 - 2.3e-07 30.6 0.1 3.8e-06 26.6 0.0 2.6 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bap31_Bap29_C PF18035.1 GBG91989.1 - 0.18 11.8 2.7 0.52 10.4 2.7 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain YabA PF06156.13 GBG91989.1 - 0.4 11.4 5.4 1.3 9.7 5.4 2.0 1 1 0 1 1 1 0 Initiation control protein YabA zf-CCHC_5 PF14787.6 GBG91989.1 - 0.69 9.7 2.6 1.6 8.5 2.6 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF1043 PF06295.12 GBG91989.1 - 3.8 7.5 8.3 7.4 6.6 5.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) RT_RNaseH_2 PF17919.1 GBG91990.1 - 1.3e-61 204.8 2.4 3e-31 107.4 0.0 3.4 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG91990.1 - 1.3e-57 192.5 4.4 4.1e-28 97.7 0.1 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase DUF1223 PF06764.11 GBG91990.1 - 1.1e-37 130.1 0.0 2.1e-35 122.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1223) Integrase_H2C2 PF17921.1 GBG91990.1 - 2.2e-14 53.3 0.6 5.3e-14 52.1 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG91990.1 - 2.8e-12 46.9 0.1 9.4e-09 35.5 0.1 2.7 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 GBG91990.1 - 0.0016 18.6 0.3 0.0046 17.2 0.3 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF2862 PF11061.8 GBG91990.1 - 0.02 14.7 0.5 4.9 7.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) Rab3-GTPase_cat PF13890.6 GBG91990.1 - 0.031 13.9 0.6 2.3 7.8 0.0 2.8 3 0 0 3 3 3 0 Rab3 GTPase-activating protein catalytic subunit DUF1904 PF08921.11 GBG91990.1 - 0.13 12.5 0.0 10 6.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) Mcp5_PH PF12814.7 GBG91990.1 - 0.16 12.1 3.1 2.3 8.3 0.2 2.6 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology zf-CCHC PF00098.23 GBG91990.1 - 0.86 9.8 2.8 2 8.7 2.8 1.7 1 0 0 1 1 1 0 Zinc knuckle Ras PF00071.22 GBG91991.1 - 1e-16 61.0 0.2 1.2e-16 60.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG91991.1 - 0.00098 19.3 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF2443 PF10398.9 GBG91991.1 - 0.0041 17.1 0.4 0.013 15.6 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2443) Acyl-ACP_TE PF01643.17 GBG91992.1 - 3e-67 226.5 0.0 7.5e-67 225.2 0.0 1.6 2 0 0 2 2 2 1 Acyl-ACP thioesterase DUF659 PF04937.15 GBG91994.1 - 2.4e-16 60.0 0.0 4.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG91994.1 - 1.8e-07 30.9 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Carb_anhydrase PF00194.21 GBG91996.1 - 2e-30 106.2 0.0 2.4e-29 102.7 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase TSC22 PF01166.18 GBG91997.1 - 0.0051 17.1 1.2 0.5 10.7 0.1 3.0 2 0 0 2 2 2 1 TSC-22/dip/bun family TRAF_BIRC3_bd PF16673.5 GBG91997.1 - 0.018 14.8 4.0 0.064 13.1 0.0 3.0 3 1 1 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain HsbA PF12296.8 GBG91997.1 - 0.032 14.6 0.2 0.057 13.9 0.2 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Tup_N PF08581.10 GBG91997.1 - 0.064 13.6 6.4 0.1 12.9 0.6 2.8 3 0 0 3 3 3 0 Tup N-terminal Trimer_CC PF08954.11 GBG91997.1 - 0.072 12.7 0.0 0.072 12.7 0.0 4.4 4 1 0 4 4 4 0 Trimerisation motif LPP PF04728.13 GBG91997.1 - 0.078 13.4 3.7 7.3 7.1 0.4 3.3 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF4404 PF14357.6 GBG91997.1 - 0.21 12.2 0.2 0.21 12.2 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Spc7 PF08317.11 GBG91997.1 - 0.25 10.2 11.1 0.53 9.1 0.4 2.4 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF3138 PF11336.8 GBG91997.1 - 0.3 9.6 1.3 1.4 7.4 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) CSN5_C PF18323.1 GBG91997.1 - 0.98 10.4 8.3 48 5.0 7.8 2.5 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF4140 PF13600.6 GBG91997.1 - 4.1 7.9 13.1 6.3 7.3 1.6 3.6 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.20 GBG91997.1 - 7 6.7 14.5 9 6.3 0.5 3.7 3 1 0 3 3 3 0 Prefoldin subunit FAM176 PF14851.6 GBG91998.1 - 0.054 13.2 0.0 0.054 13.2 0.0 3.3 4 0 0 4 4 4 0 FAM176 family PMSR PF01625.21 GBG91999.1 - 4.8e-62 208.7 0.1 6.5e-62 208.2 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase RVT_1 PF00078.27 GBG92000.1 - 1.9e-29 102.8 0.1 2.8e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG92001.1 - 2.4e-38 131.4 0.0 4.5e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Mpp10 PF04006.12 GBG92001.1 - 0.0066 14.9 16.8 0.0094 14.5 16.8 1.1 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.14 GBG92001.1 - 0.87 7.8 13.4 1.3 7.2 13.4 1.3 1 0 0 1 1 1 0 CDC45-like protein PMSR PF01625.21 GBG92002.1 - 1.1e-62 210.7 0.0 1.4e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CRCB PF02537.15 GBG92003.1 - 4.7e-28 97.3 3.6 2.2e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) WGG PF10273.9 GBG92003.1 - 9.7e-26 90.2 0.1 1.8e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 TOM6p PF15184.6 GBG92003.1 - 0.3 10.9 3.6 0.48 10.2 0.2 2.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog RNase_H2_suC PF08615.11 GBG92003.1 - 1.2 9.3 4.3 21 5.3 0.2 2.3 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_M76 PF09768.9 GBG92006.1 - 2.5e-24 86.0 0.1 2.8e-24 85.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase M76 family GCH_III PF05165.12 GBG92006.1 - 0.027 13.7 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase III Band_7 PF01145.25 GBG92007.1 - 6.2e-06 26.3 0.6 7.4e-06 26.1 0.6 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 GBG92007.1 - 0.024 13.7 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial RETICULATA-like PF11891.8 GBG92008.1 - 7.6e-63 211.5 0.1 2.1e-62 210.1 0.0 1.7 2 0 0 2 2 2 1 Protein RETICULATA-related PCRF PF03462.18 GBG92009.1 - 1e-50 172.3 0.6 2.5e-50 171.0 0.1 1.8 1 1 1 2 2 2 1 PCRF domain RF-1 PF00472.20 GBG92009.1 - 3e-33 114.2 0.0 6.5e-33 113.1 0.0 1.6 1 0 0 1 1 1 1 RF-1 domain PyrBI_leader PF08052.11 GBG92009.1 - 0.075 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 PyrBI operon leader peptide DUF4746 PF15928.5 GBG92010.1 - 3 7.2 6.0 7.8 5.8 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3223 PF11523.8 GBG92012.1 - 1.7e-23 83.3 0.3 5.4e-23 81.6 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) ORC6 PF05460.13 GBG92012.1 - 0.003 16.9 0.3 0.0047 16.3 0.1 1.3 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) OTU PF02338.19 GBG92013.1 - 0.00011 22.7 0.0 0.00028 21.4 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease GDP_Man_Dehyd PF16363.5 GBG92014.1 - 8.8e-138 459.2 0.0 1e-137 459.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GBG92014.1 - 2.4e-71 240.0 0.2 3e-71 239.7 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GBG92014.1 - 1.9e-05 23.9 0.0 3.1e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GBG92014.1 - 3.2e-05 23.2 0.0 4.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 GBG92014.1 - 0.0079 15.8 0.0 0.027 14.0 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 GBG92014.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Glyco_trans_4_2 PF13477.6 GBG92014.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like RVT_1 PF00078.27 GBG92017.1 - 7.1e-15 55.1 0.8 2.3e-14 53.4 0.1 2.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG92017.1 - 2.3e-05 24.5 5.6 0.002 18.4 0.0 3.7 4 0 0 4 4 4 2 Retrotransposon gag protein AIF-MLS PF14962.6 GBG92017.1 - 3.2 7.7 7.2 6.7 6.6 7.2 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence RVT_1 PF00078.27 GBG92018.1 - 9.9e-41 139.7 0.0 3.8e-26 92.0 0.0 3.3 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Snapin_Pallidin PF14712.6 GBG92018.1 - 0.039 14.4 0.0 0.039 14.4 0.0 2.8 2 0 0 2 2 2 0 Snapin/Pallidin AAA_lid_11 PF18198.1 GBG92019.1 - 4.9e-47 159.8 0.0 9.7e-47 158.8 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GBG92019.1 - 7.6e-35 119.6 0.0 1.7e-22 79.7 0.0 2.6 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain RT_RNaseH_2 PF17919.1 GBG92019.1 - 2.2e-33 114.2 0.0 4.6e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92019.1 - 7.5e-30 103.3 0.1 1.5e-29 102.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92019.1 - 4.1e-20 71.6 0.3 2.2e-19 69.3 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG92019.1 - 1.2e-15 57.8 0.5 3.6e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG92019.1 - 0.00021 21.4 0.0 0.0005 20.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Nop14 PF04147.12 GBG92019.1 - 0.068 11.4 14.3 0.12 10.6 14.3 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GBG92019.1 - 0.27 10.5 11.0 0.53 9.6 11.0 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GBG92019.1 - 1.2 7.2 19.2 1.9 6.5 19.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GBG92019.1 - 2.1 7.7 14.0 0.22 10.9 9.4 1.6 2 0 0 2 2 2 0 SDA1 YL1 PF05764.13 GBG92019.1 - 2.8 8.0 18.7 1.3 9.1 12.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein PPP4R2 PF09184.11 GBG92019.1 - 4.9 6.7 10.0 8.2 5.9 10.0 1.3 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.14 GBG92019.1 - 9.3 6.0 7.9 19 5.0 7.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RT_RNaseH PF17917.1 GBG92020.1 - 5.2e-10 39.6 0.1 1.7e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG92020.1 - 1.9e-06 28.4 0.0 3.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG92020.1 - 0.00036 20.3 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92020.1 - 0.0071 17.0 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92020.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF659 PF04937.15 GBG92023.1 - 5.9e-18 65.2 0.0 1.5e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG92023.1 - 0.00024 21.0 2.7 0.00055 19.9 2.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG92023.1 - 0.049 13.6 1.6 0.12 12.3 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle PLDc PF00614.22 GBG92024.1 - 0.00037 20.6 0.0 0.00092 19.3 0.0 1.7 1 0 0 1 1 1 1 Phospholipase D Active site motif Pkinase_Tyr PF07714.17 GBG92025.1 - 4.2e-61 206.5 0.0 2e-38 132.2 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG92025.1 - 1e-55 189.0 0.0 1.2e-36 126.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain ABC1 PF03109.16 GBG92025.1 - 0.0024 18.0 0.1 2.4 8.3 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 GBG92025.1 - 0.0047 16.9 0.0 2.2 8.1 0.0 3.9 3 1 1 4 4 4 1 Phosphotransferase enzyme family DUF1576 PF07613.11 GBG92025.1 - 0.018 14.5 0.0 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) Oleosin PF01277.17 GBG92025.1 - 0.023 14.4 0.3 0.045 13.5 0.3 1.4 1 0 0 1 1 1 0 Oleosin Retrotrans_gag PF03732.17 GBG92027.1 - 1e-05 25.7 2.1 0.00079 19.7 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 GBG92027.1 - 0.0015 18.4 0.7 0.0096 15.8 0.0 2.7 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain HIP1_clath_bdg PF16515.5 GBG92027.1 - 0.0084 16.7 1.9 0.0084 16.7 1.9 3.2 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 GBG92027.1 - 1.9 8.0 7.5 3.3 7.2 7.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit SET PF00856.28 GBG92028.1 - 3.6e-13 50.3 0.6 1e-11 45.6 0.0 2.8 2 0 0 2 2 2 1 SET domain GYF PF02213.16 GBG92028.1 - 8.4e-10 38.2 0.3 1.8e-09 37.1 0.3 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 GBG92028.1 - 6.4e-06 25.9 0.3 1.7e-05 24.5 0.3 1.8 1 0 0 1 1 1 1 GYF domain 2 TFIIA PF03153.13 GBG92028.1 - 0.096 12.7 30.9 0.011 15.8 16.0 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PRIMA1 PF16101.5 GBG92028.1 - 0.18 11.8 3.8 0.69 10.0 3.8 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Myb_DNA-bind_4 PF13837.6 GBG92030.1 - 3.2e-10 40.3 4.1 6e-10 39.4 4.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG92030.1 - 0.25 11.6 1.5 0.65 10.2 1.5 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG92031.1 - 9.1e-20 70.9 0.0 1.4e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92031.1 - 3e-12 46.6 0.0 5.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Pkinase_Tyr PF07714.17 GBG92034.1 - 3e-36 125.0 0.0 4.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG92034.1 - 3.3e-35 121.7 0.0 4.6e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG92034.1 - 0.01 14.7 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Nop14 PF04147.12 GBG92035.1 - 6.1 4.9 10.8 8.8 4.4 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2HC_2 PF13913.6 GBG92038.1 - 3.5 7.6 6.9 0.89 9.5 1.6 2.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Peptidase_C48 PF02902.19 GBG92039.1 - 8.5e-08 32.3 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain YjbH PF06082.11 GBG92040.1 - 0.1 11.4 1.8 0.14 11.0 1.8 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Sec8_exocyst PF04048.14 GBG92040.1 - 0.17 11.7 2.5 0.096 12.6 0.4 1.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain AAA_13 PF13166.6 GBG92040.1 - 0.26 9.9 4.5 0.36 9.4 4.5 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 GBG92040.1 - 1.7 6.5 4.5 2.3 6.0 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 GBG92040.1 - 3.3 8.2 6.4 5.6 7.4 6.4 1.3 1 0 0 1 1 1 0 AAA domain RT_RNaseH PF17917.1 GBG92041.1 - 7.6e-08 32.6 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92041.1 - 4.5e-07 29.8 0.0 9.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Choline_kin_N PF04428.14 GBG92041.1 - 0.14 11.9 0.2 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Choline kinase N terminus Ammonium_transp PF00909.21 GBG92042.1 - 8.4e-126 419.9 28.8 1.1e-125 419.5 28.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Toxin_10 PF05431.11 GBG92043.1 - 0.0072 15.8 0.4 0.021 14.3 0.4 1.8 1 0 0 1 1 1 1 Insecticidal Crystal Toxin, P42 LRR_3 PF07725.12 GBG92046.1 - 0.17 11.8 0.2 0.84 9.6 0.3 2.1 2 0 0 2 2 2 0 Leucine Rich Repeat Retrotrans_gag PF03732.17 GBG92048.1 - 0.0079 16.4 0.1 0.02 15.2 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Pkinase_Tyr PF07714.17 GBG92049.1 - 2.4e-37 128.7 0.0 5.6e-36 124.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG92049.1 - 4.7e-37 127.8 0.0 4.8e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG92049.1 - 0.0064 16.4 0.0 0.053 13.4 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG92049.1 - 0.052 12.3 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RT_RNaseH PF17917.1 GBG92050.1 - 7.2e-23 80.9 0.0 2.3e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92050.1 - 6.4e-22 77.5 0.0 1.4e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92050.1 - 1.6e-15 56.9 0.4 4.5e-15 55.5 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 GBG92050.1 - 0.043 13.9 2.3 0.11 12.6 2.3 1.8 1 0 0 1 1 1 0 Zinc knuckle KdpD PF02702.17 GBG92050.1 - 0.086 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Topo_Zn_Ribbon PF08272.11 GBG92050.1 - 0.16 11.6 0.2 0.51 10.0 0.2 1.9 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DMPK_coil PF08826.10 GBG92051.1 - 1.9 8.6 9.9 0.71 10.0 6.3 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like IQ PF00612.27 GBG92053.1 - 4.7e-05 22.8 10.8 0.022 14.5 5.4 3.3 2 0 0 2 2 2 2 IQ calmodulin-binding motif EF-hand_7 PF13499.6 GBG92054.1 - 7.8e-20 71.1 14.1 1.4e-14 54.3 2.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG92054.1 - 7.9e-19 65.7 9.1 5.8e-07 28.6 0.7 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GBG92054.1 - 2.4e-17 61.3 3.3 0.00023 20.8 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 GBG92054.1 - 8e-13 48.0 8.3 1.9e-10 40.4 0.8 4.3 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 GBG92054.1 - 1.9e-10 40.9 0.3 1.2e-05 25.6 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GBG92054.1 - 2.5e-07 29.9 4.8 0.00015 21.1 0.5 3.9 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 GBG92054.1 - 0.0081 16.1 0.0 7.1 6.6 0.0 2.9 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand BST2 PF16716.5 GBG92054.1 - 0.013 16.1 4.7 0.013 16.1 4.7 9.8 5 2 6 12 12 12 0 Bone marrow stromal antigen 2 Caleosin PF05042.13 GBG92054.1 - 0.19 11.7 0.0 47 3.9 0.0 3.1 2 1 1 3 3 3 0 Caleosin related protein CARD_2 PF16739.5 GBG92055.1 - 0.09 12.8 0.3 0.33 10.9 0.1 2.0 2 0 0 2 2 2 0 Caspase recruitment domain ATP-synt_E_2 PF08112.11 GBG92055.1 - 0.32 11.3 1.1 0.86 9.9 1.1 1.6 1 0 0 1 1 1 0 ATP synthase epsilon subunit DUF4404 PF14357.6 GBG92055.1 - 2.2 9.0 6.0 2.3 8.9 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Cyt-b5 PF00173.28 GBG92056.1 - 4.5e-05 23.5 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RVT_1 PF00078.27 GBG92057.1 - 4e-29 101.7 0.0 6.2e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG92057.1 - 5.7e-18 64.8 0.3 1.4e-17 63.6 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92057.1 - 1.1e-11 44.9 0.0 2.7e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain EzrA PF06160.12 GBG92057.1 - 0.22 9.6 2.7 0.41 8.8 2.7 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GSH-S_ATP PF02955.16 GBG92057.1 - 0.24 10.8 0.0 0.43 10.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain RCDG1 PF15725.5 GBG92057.1 - 1.9 9.0 11.5 6.3 7.3 11.5 1.9 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein SNAPc_SNAP43 PF09808.9 GBG92058.1 - 5.6e-30 104.7 0.0 9e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 WD40 PF00400.32 GBG92059.1 - 3.7e-34 116.2 12.4 1.4e-05 25.8 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG92059.1 - 1.2e-14 54.3 0.0 0.00061 20.0 0.0 5.3 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG92059.1 - 1.7e-06 27.2 0.0 0.021 13.8 0.0 3.5 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GBG92059.1 - 2.1e-05 23.4 0.1 0.24 10.0 0.0 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 GBG92059.1 - 0.00074 18.5 0.1 3.6 6.4 0.0 3.0 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 GBG92059.1 - 0.0026 18.2 1.0 2.7 8.6 0.0 3.7 3 0 0 3 3 3 1 PQQ-like domain Phage_Mu_Gp45 PF06890.12 GBG92059.1 - 0.0065 16.2 0.0 0.062 13.0 0.0 2.2 2 0 0 2 2 2 1 Bacteriophage Mu Gp45 protein PD40 PF07676.12 GBG92059.1 - 0.0071 16.3 0.1 9.7 6.3 0.1 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 GBG92059.1 - 0.023 13.2 0.0 0.14 10.7 0.0 1.9 1 1 1 2 2 2 0 Cytochrome D1 heme domain Lactonase PF10282.9 GBG92059.1 - 0.14 11.4 0.0 0.42 9.8 0.0 1.8 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller TruB_C PF09142.11 GBG92059.1 - 3 7.7 5.3 27 4.6 0.0 3.7 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal ANAPC4_WD40 PF12894.7 GBG92060.1 - 0.00042 20.6 0.3 6.4 7.2 0.1 4.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GBG92060.1 - 0.24 11.2 0.0 0.71 9.7 0.1 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 GBG92060.1 - 0.58 11.1 3.6 6.6 7.8 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat DnaJ_CXXCXGXG PF00684.19 GBG92061.1 - 0.0044 17.4 6.3 0.0044 17.4 6.3 2.9 1 1 1 2 2 2 1 DnaJ central domain Ribosomal_60s PF00428.19 GBG92063.1 - 0.0051 17.4 4.6 0.0051 17.4 4.6 4.1 1 1 2 3 3 3 1 60s Acidic ribosomal protein Mpp10 PF04006.12 GBG92063.1 - 0.029 12.8 37.2 0.035 12.6 37.2 1.2 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 GBG92063.1 - 0.13 10.6 32.2 0.16 10.2 32.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG92063.1 - 0.27 9.4 42.7 0.34 9.1 42.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG92063.1 - 0.45 9.9 45.2 0.57 9.6 45.2 1.1 1 0 0 1 1 1 0 SDA1 CCSAP PF15748.5 GBG92063.1 - 0.55 10.4 16.8 0.6 10.2 16.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Hid1 PF12722.7 GBG92063.1 - 1.4 6.9 12.9 1.5 6.8 12.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_11 PF13086.6 GBG92063.1 - 3.8 7.2 9.5 4.9 6.9 9.5 1.3 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 GBG92063.1 - 5 6.2 14.3 6.2 5.9 14.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 GBG92063.1 - 6.6 6.7 10.9 9.1 6.2 10.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A gag-asp_proteas PF13975.6 GBG92064.1 - 4.5e-07 30.3 0.0 9.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92064.1 - 7e-07 29.8 0.0 1.9e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92064.1 - 1.5e-05 24.8 0.0 4.4e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG92064.1 - 4.1e-05 23.2 0.1 7.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG92064.1 - 5.2e-05 23.0 0.0 8.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG92065.1 - 0.0053 17.3 13.0 0.19 12.4 0.0 3.6 3 0 0 3 3 3 2 SlyX Retrotrans_gag PF03732.17 GBG92065.1 - 0.0073 16.6 5.8 2.7 8.4 0.0 3.8 4 0 0 4 4 4 2 Retrotransposon gag protein CLZ PF16526.5 GBG92065.1 - 0.15 12.4 5.1 3.6 8.0 0.5 3.7 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FAM76 PF16046.5 GBG92065.1 - 0.39 10.0 5.9 0.57 9.5 5.9 1.2 1 0 0 1 1 1 0 FAM76 protein ABC_tran_Xtn PF12848.7 GBG92065.1 - 1.7 8.7 9.6 5 7.2 7.8 2.3 2 0 0 2 2 2 0 ABC transporter DivIC PF04977.15 GBG92065.1 - 6.8 6.5 9.6 5.3 6.9 0.1 3.3 3 0 0 3 3 3 0 Septum formation initiator DsrH PF04077.12 GBG92066.1 - 0.0011 19.0 1.4 7.3 6.8 0.0 5.1 1 1 5 7 7 7 1 DsrH like protein CstA PF02554.14 GBG92066.1 - 0.0031 16.5 5.5 4 6.3 0.1 4.2 3 1 2 5 5 5 4 Carbon starvation protein CstA HTH_Tnp_1 PF01527.20 GBG92066.1 - 0.18 12.2 7.4 2.3 8.6 0.1 3.6 2 2 2 4 4 4 0 Transposase Sec62 PF03839.16 GBG92067.1 - 2.4e-21 76.2 0.1 4.4e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 Translocation protein Sec62 CrgA PF06781.12 GBG92067.1 - 0.013 15.5 0.7 0.044 13.8 0.0 2.1 2 0 0 2 2 2 0 Cell division protein CrgA Glycos_transf_2 PF00535.26 GBG92068.1 - 1.1e-11 44.8 0.0 5.6e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG92068.1 - 1.4e-09 38.2 0.1 6.5e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GBG92068.1 - 9.1e-07 28.6 0.0 3.3e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GBG92068.1 - 0.00027 20.9 0.1 0.0006 19.8 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF659 PF04937.15 GBG92069.1 - 1.6e-36 125.5 0.8 2.5e-36 124.8 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) WRC PF08879.10 GBG92070.1 - 2.7e-11 43.0 12.2 1.1e-08 34.6 4.4 3.0 2 0 0 2 2 2 2 WRC JmjC PF02373.22 GBG92070.1 - 5.8e-11 42.8 2.1 6.6e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 GBG92070.1 - 1.6e-06 28.3 15.0 1.6e-06 28.3 15.0 3.1 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 GBG92070.1 - 0.12 12.1 0.0 0.43 10.3 0.0 1.9 1 0 0 1 1 1 0 Cupin domain gag-asp_proteas PF13975.6 GBG92071.1 - 9.7e-08 32.5 0.1 2.7e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92071.1 - 6.3e-06 26.8 0.1 1.7e-05 25.4 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92071.1 - 0.00022 21.0 0.1 0.00035 20.3 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92071.1 - 0.004 16.9 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG92071.1 - 0.014 15.0 0.3 0.03 14.0 0.3 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like gag-asp_proteas PF13975.6 GBG92072.1 - 0.00011 22.6 0.1 0.00027 21.4 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92072.1 - 0.00049 20.7 0.1 0.00096 19.8 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92072.1 - 0.045 13.5 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease cNMP_binding PF00027.29 GBG92072.1 - 0.073 13.1 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain RVP_2 PF08284.11 GBG92072.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Nop53 PF07767.11 GBG92074.1 - 4.7 6.5 23.8 5.2 6.3 23.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Dimer_Tnp_hAT PF05699.14 GBG92076.1 - 0.00034 20.3 0.2 0.00058 19.6 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVP_2 PF08284.11 GBG92077.1 - 3e-07 30.3 0.0 1e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG92077.1 - 0.0006 20.3 0.0 0.0016 18.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92077.1 - 0.0034 18.0 0.1 0.012 16.2 0.1 2.0 1 1 0 1 1 1 1 Aspartyl protease SlyX PF04102.12 GBG92077.1 - 0.0087 16.7 0.3 0.0087 16.7 0.3 3.5 4 0 0 4 4 4 1 SlyX Retrotrans_gag PF03732.17 GBG92077.1 - 0.026 14.8 0.0 0.086 13.1 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG92077.1 - 0.038 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF2730 PF10805.8 GBG92077.1 - 0.1 12.7 0.2 0.28 11.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) PTS_IIA PF02255.16 GBG92077.1 - 0.59 10.2 5.1 3.7 7.6 1.7 3.0 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DivIC PF04977.15 GBG92077.1 - 6.3 6.6 7.6 4.1 7.3 0.1 3.0 2 0 0 2 2 2 0 Septum formation initiator PHD PF00628.29 GBG92079.1 - 3.2e-12 46.2 29.2 5.2e-10 39.1 8.3 3.1 2 1 1 3 3 3 2 PHD-finger GGACT PF06094.12 GBG92079.1 - 3.1e-07 31.0 0.1 3.9e-06 27.5 0.1 2.5 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like SET PF00856.28 GBG92079.1 - 0.0085 16.5 0.0 0.11 12.9 0.0 2.7 2 1 0 2 2 2 1 SET domain PHF5 PF03660.14 GBG92079.1 - 0.049 13.8 15.9 0.028 14.6 6.0 2.7 2 0 0 2 2 2 0 PHF5-like protein Mito_fiss_reg PF05308.11 GBG92079.1 - 0.82 9.7 22.0 1.9 8.5 4.2 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 GBG92079.1 - 7.9 5.9 28.9 0.48 9.9 6.2 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DSPc PF00782.20 GBG92080.1 - 8e-11 41.9 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GBG92080.1 - 4.1e-08 33.1 0.1 6.7e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 GBG92080.1 - 1.1e-05 25.2 0.1 2.3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 GBG92080.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3750 PF12570.8 GBG92080.1 - 0.31 11.7 1.4 1.1e+02 3.5 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3750) Plasmodium_HRP PF05403.11 GBG92080.1 - 3 7.6 45.8 0.75 9.5 4.2 4.6 1 1 1 3 3 3 0 Plasmodium histidine-rich protein (HRPII/III) AA_permease_2 PF13520.6 GBG92081.1 - 2.2e-37 128.9 31.6 3.3e-37 128.4 31.6 1.2 1 0 0 1 1 1 1 Amino acid permease Ins134_P3_kin PF05770.11 GBG92082.1 - 5.4e-50 169.7 0.0 7.1e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 GBG92082.1 - 1.4e-19 70.2 0.0 2.6e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain DUF4783 PF16022.5 GBG92083.1 - 0.054 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) Glyco_transf_5 PF08323.11 GBG92084.1 - 1.2e-67 228.2 0.0 2.4e-67 227.2 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GBG92084.1 - 2.3e-18 66.3 0.0 3.8e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG92084.1 - 3.6e-14 53.4 0.1 9.4e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 TOH_N PF12549.8 GBG92084.1 - 0.086 12.7 3.7 4.1 7.4 0.3 2.9 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal Glyco_transf_4 PF13439.6 GBG92084.1 - 0.11 12.5 0.1 17 5.3 0.2 2.6 2 0 0 2 2 2 0 Glycosyltransferase Family 4 DUF2284 PF10050.9 GBG92084.1 - 1.2 8.8 6.9 8.1 6.2 1.6 2.4 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) Glycos_transf_2 PF00535.26 GBG92085.1 - 4.9e-27 94.8 0.1 6.6e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GBG92085.1 - 3.5e-12 46.7 0.1 4.4e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GBG92085.1 - 7e-09 35.5 0.0 8.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 GBG92085.1 - 0.0031 18.0 0.0 0.0048 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PEP-utilisers_N PF05524.13 GBG92086.1 - 0.097 12.8 3.8 0.32 11.2 2.8 2.2 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal TBCC_N PF16752.5 GBG92086.1 - 0.48 10.9 7.2 1.1 9.8 7.2 1.6 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Sulfotransfer_3 PF13469.6 GBG92087.1 - 3.8e-06 27.5 0.0 1.7e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 GBG92087.1 - 0.0075 15.8 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_2 PF03567.14 GBG92087.1 - 0.012 15.5 0.0 0.3 10.9 0.0 2.6 2 1 0 2 2 2 0 Sulfotransferase family RVT_1 PF00078.27 GBG92088.1 - 3.8e-10 39.7 0.1 6.6e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG92088.1 - 7.5e-05 23.3 0.0 0.00016 22.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92088.1 - 8.4e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG92088.1 - 0.0075 16.8 0.0 0.028 15.0 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92088.1 - 0.21 11.4 0.0 0.76 9.6 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG92089.1 - 1.2e-18 67.0 0.0 3e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92089.1 - 5.9e-11 42.3 0.0 1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92089.1 - 9.2e-09 35.5 0.0 2.6e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BRCT PF00533.26 GBG92089.1 - 0.00029 21.2 0.1 0.27 11.7 0.0 3.2 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GBG92089.1 - 0.0024 17.8 0.5 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain zf-RING_6 PF14835.6 GBG92089.1 - 0.022 14.6 0.2 0.051 13.4 0.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF659 PF04937.15 GBG92093.1 - 4.7e-21 75.2 0.0 8.6e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92093.1 - 0.0003 20.5 0.2 0.00088 19.0 0.2 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pentapeptide_2 PF01469.18 GBG92094.1 - 0.16 11.9 7.8 0.33 10.9 7.8 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) RT_RNaseH_2 PF17919.1 GBG92095.1 - 3.2e-25 88.1 0.0 9.9e-25 86.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92095.1 - 3e-24 85.3 0.0 6.6e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HEPN_AbiU2 PF18734.1 GBG92095.1 - 0.72 9.3 16.3 0.91 9.0 1.7 4.0 4 0 0 4 4 4 0 AbiU2 RVT_1 PF00078.27 GBG92096.1 - 1.9e-31 109.3 0.0 3.6e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92096.1 - 5.3e-28 97.4 1.4 1.2e-27 96.2 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92096.1 - 7.1e-28 96.6 0.0 2e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DNA_pack_N PF02500.15 GBG92096.1 - 0.068 13.0 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Phage_GPO PF05929.11 GBG92096.1 - 0.091 12.4 0.1 0.091 12.4 0.1 3.8 4 0 0 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4392 PF14336.6 GBG92096.1 - 0.18 11.2 1.1 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) LMBR1 PF04791.16 GBG92096.1 - 0.31 9.9 3.8 0.092 11.6 0.6 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein RVT_1 PF00078.27 GBG92097.1 - 1.8e-59 201.0 1.7 4e-32 111.5 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92097.1 - 1.1e-32 112.0 0.0 2.4e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 GBG92097.1 - 3.4e-30 104.9 0.1 8.5e-30 103.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG92097.1 - 4.7e-28 97.6 0.2 1e-27 96.5 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Dimer_Tnp_hAT PF05699.14 GBG92097.1 - 6e-05 22.8 0.1 0.00015 21.5 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Integrase_H2C2 PF17921.1 GBG92098.1 - 2.7e-19 69.0 0.2 7.3e-19 67.6 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG92098.1 - 7.1e-17 61.6 0.0 1.8e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92098.1 - 9.5e-12 44.9 0.1 1.8e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92098.1 - 3e-10 40.0 0.0 7.8e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92098.1 - 1.9e-07 31.3 0.0 4.9e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG92098.1 - 8e-05 23.2 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92098.1 - 0.00035 21.1 0.0 0.00066 20.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG92098.1 - 0.00044 20.0 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG92098.1 - 0.0043 16.8 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG92098.1 - 0.09 13.0 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger COX_ARM PF06481.14 GBG92098.1 - 0.25 11.3 0.6 30 4.6 0.1 3.2 3 0 0 3 3 3 0 COX Aromatic Rich Motif RVT_1 PF00078.27 GBG92099.1 - 1.7e-28 99.7 0.1 2.8e-28 99.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG92099.1 - 2e-06 28.3 0.0 4.8e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92099.1 - 2.1e-06 27.5 0.0 4.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease LysM PF01476.20 GBG92099.1 - 1.8e-05 24.7 0.4 7.5e-05 22.7 0.0 2.3 3 0 0 3 3 3 1 LysM domain gag-asp_proteas PF13975.6 GBG92099.1 - 5.3e-05 23.7 0.0 0.00013 22.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92099.1 - 0.0023 17.7 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF4939 PF16297.5 GBG92100.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) EzrA PF06160.12 GBG92100.1 - 0.36 8.9 4.6 0.54 8.4 4.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 GBG92100.1 - 0.5 9.9 3.7 1 8.8 3.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran PF00005.27 GBG92101.1 - 8.2e-32 110.6 0.0 1.6e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GBG92101.1 - 1.9e-08 34.3 0.2 2.7e-08 33.8 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 GBG92101.1 - 1.8e-05 24.7 0.0 0.027 14.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GBG92101.1 - 0.00031 21.2 0.0 0.0006 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GBG92101.1 - 0.00059 19.5 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 GBG92101.1 - 0.0039 16.8 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GBG92101.1 - 0.004 16.5 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 GBG92101.1 - 0.0045 17.2 0.0 0.0093 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GBG92101.1 - 0.0055 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GBG92101.1 - 0.0071 16.6 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 GBG92101.1 - 0.018 15.1 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_7 PF12775.7 GBG92101.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 GBG92101.1 - 0.022 14.7 0.0 0.059 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 GBG92101.1 - 0.069 13.2 0.0 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 GBG92101.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 GBG92101.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase T2SSE PF00437.20 GBG92101.1 - 0.12 11.4 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 GBG92101.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 GBG92101.1 - 0.3 9.9 1.1 0.31 9.8 0.0 1.4 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) RVT_1 PF00078.27 GBG92102.1 - 7e-30 104.2 0.1 1.2e-29 103.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG92102.1 - 8.1e-06 26.0 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG92102.1 - 7e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain EzrA PF06160.12 GBG92102.1 - 0.029 12.6 0.0 0.05 11.8 0.0 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF484 PF04340.12 GBG92102.1 - 4 7.1 10.7 1.5 8.4 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF484 RVT_1 PF00078.27 GBG92103.1 - 7.1e-27 94.4 0.1 1.3e-26 93.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92103.1 - 5e-24 84.2 0.0 1.4e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92103.1 - 3e-22 78.9 0.0 8.8e-22 77.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92103.1 - 5.7e-17 61.6 1.0 3.3e-16 59.1 0.3 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG92103.1 - 0.0017 18.1 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG92103.1 - 0.0057 16.8 0.1 0.016 15.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger CENP-K PF11802.8 GBG92103.1 - 0.023 14.3 3.6 0.049 13.2 3.6 1.5 1 0 0 1 1 1 0 Centromere-associated protein K TFIIA PF03153.13 GBG92103.1 - 2.4 8.1 16.2 3.5 7.5 16.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Caudo_TAP PF02413.17 GBG92103.1 - 4.9 7.3 10.2 0.84 9.8 1.0 2.9 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK ABC_tran PF00005.27 GBG92104.1 - 2.3e-12 47.6 0.0 3.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GBG92104.1 - 0.00032 20.5 0.0 0.00051 19.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region cobW PF02492.19 GBG92104.1 - 0.0034 17.0 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 GBG92104.1 - 0.0093 15.9 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GBG92104.1 - 0.011 16.2 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GBG92104.1 - 0.039 14.2 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GBG92104.1 - 0.052 12.6 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 GBG92104.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GBG92104.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 GBG92104.1 - 0.21 11.6 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RT_RNaseH PF17917.1 GBG92105.1 - 1.4e-17 63.9 0.0 2.7e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92105.1 - 3.6e-14 52.6 0.0 7.2e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92105.1 - 4.4e-14 52.3 0.7 8e-14 51.5 0.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Nif11 PF07862.11 GBG92105.1 - 0.031 14.6 0.0 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Nif11 domain rve PF00665.26 GBG92105.1 - 0.1 12.8 0.0 0.64 10.2 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain RVT_1 PF00078.27 GBG92106.1 - 1.7e-25 89.9 0.0 4.3e-25 88.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG92106.1 - 1.2e-06 28.7 0.3 1.4e-05 25.3 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG92106.1 - 0.028 14.7 0.5 0.19 12.0 0.0 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein AP1AR PF15745.5 GBG92107.1 - 0.052 13.2 5.6 0.083 12.5 5.6 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF4407 PF14362.6 GBG92107.1 - 0.47 9.7 8.2 0.67 9.2 5.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 GBG92107.1 - 6 6.8 11.3 10 6.0 0.1 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain Retrotrans_gag PF03732.17 GBG92108.1 - 0.00093 19.4 1.5 0.005 17.1 0.2 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG92108.1 - 0.0036 17.1 1.0 0.012 15.4 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) AIP3 PF03915.13 GBG92108.1 - 0.041 13.0 2.7 0.067 12.3 2.7 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Lipin_mid PF16876.5 GBG92108.1 - 0.043 14.0 1.2 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain RT_RNaseH_2 PF17919.1 GBG92109.1 - 4.6e-33 113.2 0.0 9.4e-33 112.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92109.1 - 4.3e-29 100.9 0.2 1.9e-28 98.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92109.1 - 1.9e-28 99.5 0.0 3.3e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Casc1_N PF15927.5 GBG92109.1 - 0.72 9.5 11.2 1.6 8.4 11.2 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Phage_GPO PF05929.11 GBG92109.1 - 4.7 6.8 5.9 0.63 9.6 0.0 2.1 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase YL1 PF05764.13 GBG92111.1 - 0.2 11.7 22.9 0.27 11.3 22.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG92111.1 - 1.9 7.8 21.5 2.6 7.3 21.5 1.1 1 0 0 1 1 1 0 BUD22 Menin PF05053.13 GBG92111.1 - 2.8 6.2 6.0 4.4 5.5 6.0 1.2 1 0 0 1 1 1 0 Menin DUF1387 PF07139.11 GBG92111.1 - 4.5 6.9 12.0 5.8 6.6 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SDA1 PF05285.12 GBG92111.1 - 5.2 6.4 19.3 7 6.0 19.3 1.1 1 0 0 1 1 1 0 SDA1 DUF659 PF04937.15 GBG92112.1 - 8.8e-35 119.8 0.0 1.9e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92112.1 - 3.6e-07 29.9 2.5 6.9e-07 29.0 1.6 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 GBG92113.1 - 8.9e-26 90.8 0.1 1.6e-25 89.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2730 PF10805.8 GBG92113.1 - 0.0067 16.5 0.5 0.016 15.3 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) SlyX PF04102.12 GBG92113.1 - 0.01 16.4 1.3 0.01 16.4 1.3 3.4 2 1 1 3 3 3 0 SlyX P4Ha_N PF08336.11 GBG92113.1 - 0.066 13.2 0.4 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Matrilin_ccoil PF10393.9 GBG92113.1 - 0.084 12.7 0.5 0.084 12.7 0.5 2.6 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin PEP-utilisers_N PF05524.13 GBG92113.1 - 0.099 12.8 0.5 0.23 11.7 0.5 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal SLX9 PF15341.6 GBG92113.1 - 0.12 12.7 2.8 0.11 12.8 1.3 1.6 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 TolA_bind_tri PF16331.5 GBG92113.1 - 0.18 11.9 6.2 0.29 11.2 5.1 1.9 1 1 1 2 2 2 0 TolA binding protein trimerisation Fez1 PF06818.15 GBG92113.1 - 0.59 10.6 4.5 0.48 10.8 1.0 2.0 2 0 0 2 2 2 0 Fez1 Retrotrans_gag PF03732.17 GBG92114.1 - 0.00016 21.9 0.3 0.00036 20.8 0.1 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein FAT PF02259.23 GBG92114.1 - 0.012 14.9 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 FAT domain zf-CCHC PF00098.23 GBG92115.1 - 1.9e-05 24.5 0.9 4.9e-05 23.2 0.9 1.8 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 GBG92115.1 - 0.052 13.0 0.0 0.36 10.3 0.0 2.1 1 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG92115.1 - 0.47 10.3 2.5 0.46 10.4 0.2 2.1 2 0 0 2 2 2 0 Zinc knuckle RHSP PF07999.11 GBG92119.1 - 0.28 9.9 0.8 1.6 7.5 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon hot spot protein Integrase_H2C2 PF17921.1 GBG92120.1 - 8.8e-12 45.0 1.9 1.5e-11 44.2 0.1 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG92120.1 - 2.2e-06 27.8 0.0 6.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG92120.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG92120.1 - 0.053 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger DUF4139 PF13598.6 GBG92120.1 - 2.7 7.6 4.6 0.78 9.4 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4139) zf-C2H2_10 PF16588.5 GBG92121.1 - 0.014 15.2 2.8 0.014 15.2 2.8 1.8 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC PF00098.23 GBG92121.1 - 0.28 11.3 2.1 0.65 10.2 2.1 1.7 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG92122.1 - 4e-11 43.1 0.0 8.5e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92122.1 - 2.7e-09 36.9 0.0 6.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 GBG92122.1 - 0.073 13.4 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG92122.1 - 0.083 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG92123.1 - 3.7e-34 116.7 0.0 9.8e-34 115.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92123.1 - 1.7e-30 105.4 0.0 3.7e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92123.1 - 3.6e-30 105.1 0.9 5.8e-30 104.5 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG92123.1 - 1e-19 70.3 0.1 2.4e-19 69.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92123.1 - 1.6e-12 47.6 0.0 7.7e-12 45.5 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG92124.1 - 1.8e-20 72.8 0.0 4.1e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92124.1 - 5.9e-15 55.5 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG92124.1 - 4.7e-11 42.6 0.0 8.6e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92124.1 - 3e-07 30.7 0.0 6.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RNA_pol_3_Rpc31 PF11705.8 GBG92124.1 - 0.0072 16.6 3.0 0.0072 16.6 3.0 4.2 3 1 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 GBG92124.1 - 0.011 15.5 7.0 0.011 15.5 7.0 4.3 3 1 1 4 4 4 0 Cwf15/Cwc15 cell cycle control protein DUF2385 PF09539.10 GBG92124.1 - 0.054 14.0 0.2 1 10.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) gag-asp_proteas PF13975.6 GBG92125.1 - 1.6e-06 28.6 0.0 5.8e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92125.1 - 0.00044 20.8 0.1 0.0012 19.5 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92125.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease EF-hand_1 PF00036.32 GBG92126.1 - 1.7e-06 27.1 5.7 0.0069 15.9 0.8 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GBG92126.1 - 4.7e-06 26.1 7.8 0.0049 16.7 1.0 2.6 2 0 0 2 2 2 2 EF-hand domain Ion_trans PF00520.31 GBG92126.1 - 1.4e-05 24.4 22.8 1.4e-05 24.4 22.8 2.4 2 1 0 2 2 2 1 Ion transport protein EF-hand_7 PF13499.6 GBG92126.1 - 0.00011 22.6 5.8 0.00034 21.0 5.8 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GBG92126.1 - 0.00095 19.0 0.9 0.0022 17.8 0.9 1.7 1 0 0 1 1 1 1 EF-hand domain pair PKD_channel PF08016.12 GBG92126.1 - 0.012 14.3 14.3 0.04 12.6 7.8 2.2 2 0 0 2 2 2 0 Polycystin cation channel SPARC_Ca_bdg PF10591.9 GBG92126.1 - 0.12 12.7 1.0 0.3 11.4 0.3 1.8 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 GBG92126.1 - 0.62 9.7 6.5 3.4 7.3 0.8 2.4 2 0 0 2 2 2 0 EF hand RVP_2 PF08284.11 GBG92127.1 - 3e-10 40.0 0.0 1e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92127.1 - 3.3e-08 34.1 0.0 9.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92127.1 - 1.2e-06 29.0 0.0 6e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92127.1 - 0.0011 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG92127.1 - 0.0034 17.6 1.2 0.0099 16.1 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4187 PF13821.6 GBG92127.1 - 0.017 14.9 0.7 0.046 13.5 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) SlyX PF04102.12 GBG92127.1 - 0.068 13.8 3.2 0.12 13.0 0.7 2.6 2 0 0 2 2 2 0 SlyX RVP PF00077.20 GBG92127.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease PRAS PF15798.5 GBG92129.1 - 0.05 14.2 0.5 0.064 13.9 0.5 1.2 1 0 0 1 1 1 0 Proline-rich AKT1 substrate 1 FCP1_C PF09309.10 GBG92130.1 - 0.063 13.2 3.9 0.13 12.1 3.9 1.5 1 0 0 1 1 1 0 FCP1, C-terminal HSP70 PF00012.20 GBG92132.1 - 5.5e-143 477.3 0.0 6.6e-143 477.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG92132.1 - 3.2e-13 49.2 0.7 3.6e-12 45.8 0.0 2.3 3 0 0 3 3 3 1 MreB/Mbl protein StbA PF06406.11 GBG92132.1 - 0.0045 16.3 0.0 0.011 14.9 0.0 1.6 2 0 0 2 2 2 1 StbA protein AA_permease_2 PF13520.6 GBG92135.1 - 0.08 11.8 21.8 0.1 11.4 21.8 1.1 1 0 0 1 1 1 0 Amino acid permease Tetraspanin PF00335.20 GBG92135.1 - 0.31 10.7 9.3 0.44 10.2 9.3 1.4 1 0 0 1 1 1 0 Tetraspanin family Ribosomal_60s PF00428.19 GBG92136.1 - 0.031 14.9 1.0 0.031 14.9 1.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2407_C PF13373.6 GBG92136.1 - 0.12 12.5 1.3 0.36 11.0 1.3 1.8 1 0 0 1 1 1 0 DUF2407 C-terminal domain CCDC53 PF10152.9 GBG92136.1 - 0.43 11.0 16.8 0.14 12.6 3.3 2.3 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Macoilin PF09726.9 GBG92136.1 - 0.54 8.8 21.6 0.75 8.3 21.6 1.2 1 0 0 1 1 1 0 Macoilin family FAM76 PF16046.5 GBG92136.1 - 0.65 9.3 12.6 1.6 8.1 12.6 1.7 1 0 0 1 1 1 0 FAM76 protein HSP70 PF00012.20 GBG92137.1 - 2.2e-89 300.3 0.0 7.3e-64 216.0 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG92137.1 - 1.5e-19 70.4 0.0 3.7e-07 29.8 0.0 4.8 4 1 0 4 4 4 4 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG92137.1 - 4.2e-11 42.3 0.0 6.7e-08 31.7 0.0 3.2 3 0 0 3 3 3 2 MreB/Mbl protein RVP_2 PF08284.11 GBG92138.1 - 6.3e-06 26.0 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92138.1 - 0.00032 21.3 0.0 0.00061 20.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92138.1 - 0.0022 18.5 0.0 0.0039 17.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92138.1 - 0.077 12.8 0.0 0.29 10.9 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease HSP70 PF00012.20 GBG92139.1 - 2.6e-112 376.0 0.0 1.1e-97 327.7 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GBG92139.1 - 3.1e-08 32.8 0.1 2.1e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Myb_DNA-bind_4 PF13837.6 GBG92139.1 - 0.00086 19.6 1.7 0.0011 19.3 0.5 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain HSP70 PF00012.20 GBG92140.1 - 8.8e-81 271.9 0.3 1e-80 271.6 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG92140.1 - 1.2e-13 50.7 0.2 1.8e-13 50.0 0.2 1.3 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 GBG92140.1 - 0.00089 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MutL PF13941.6 GBG92140.1 - 0.054 12.1 0.1 0.12 11.0 0.1 1.5 1 1 0 2 2 2 0 MutL protein CPSF73-100_C PF11718.8 GBG92140.1 - 0.076 12.6 0.1 5.5 6.5 0.0 2.4 2 1 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term StbA PF06406.11 GBG92140.1 - 0.093 12.0 0.2 0.18 11.0 0.1 1.4 1 1 0 1 1 1 0 StbA protein RT_RNaseH_2 PF17919.1 GBG92141.1 - 1e-23 83.2 0.0 6.9e-23 80.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92141.1 - 8.5e-23 80.6 0.0 1.7e-21 76.5 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92141.1 - 6.4e-14 51.8 0.7 6.4e-14 51.8 0.7 3.1 4 0 0 4 4 3 1 Integrase zinc binding domain Kelch_5 PF13854.6 GBG92141.1 - 1e-11 44.5 0.8 4e-05 23.5 0.0 2.9 3 0 0 3 3 3 2 Kelch motif RVT_1 PF00078.27 GBG92141.1 - 1.2e-07 31.5 0.1 2.5e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_4 PF13418.6 GBG92141.1 - 1.7e-07 31.2 0.2 0.015 15.3 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GBG92141.1 - 2.2e-07 30.6 0.2 0.002 18.0 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 GBG92141.1 - 5.4e-06 25.9 0.2 0.01 15.4 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 GBG92141.1 - 0.00033 20.8 3.9 0.0045 17.2 0.3 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Chromo PF00385.24 GBG92141.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG92141.1 - 0.031 14.5 0.2 0.13 12.5 0.2 2.2 1 0 0 1 1 1 0 H2C2 zinc finger FAM27 PF15832.5 GBG92141.1 - 0.038 14.5 0.1 0.038 14.5 0.1 3.1 3 0 0 3 3 2 0 FAM27 D and E protein family DUF167 PF02594.16 GBG92141.1 - 0.069 13.3 0.3 0.18 11.9 0.3 1.7 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 DUF3037 PF11236.8 GBG92141.1 - 2.7 8.4 7.3 4.7 7.7 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3037) RT_RNaseH_2 PF17919.1 GBG92142.1 - 1.3e-30 105.4 0.0 3.5e-30 104.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92142.1 - 3.5e-28 98.0 0.4 8.5e-28 96.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92142.1 - 2.5e-16 59.5 0.5 5.7e-16 58.4 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92142.1 - 4.2e-15 56.0 0.0 1.1e-14 54.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Kelch_1 PF01344.25 GBG92143.1 - 1.2e-16 60.0 1.2 1.4e-07 30.9 0.1 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 GBG92143.1 - 2.7e-14 53.0 2.9 1.6e-06 28.3 0.0 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GBG92143.1 - 2.5e-13 49.7 5.5 6.9e-07 29.1 0.1 2.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 GBG92143.1 - 7.2e-13 48.3 0.7 1.2e-05 25.4 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 GBG92143.1 - 3.4e-08 33.2 0.6 0.0041 17.0 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 GBG92143.1 - 2.3e-07 30.7 2.3 5.2e-06 26.4 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Gly_acyl_tr_N PF06021.11 GBG92143.1 - 0.012 15.7 0.2 0.012 15.7 0.2 3.1 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase APH PF01636.23 GBG92144.1 - 6.5e-42 144.1 0.0 1.7e-41 142.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 GBG92144.1 - 2.4e-37 128.4 4.2 5e-37 127.4 4.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GBG92144.1 - 2.5e-18 66.0 0.0 4.5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GBG92144.1 - 7.6e-12 45.7 3.9 1.6e-11 44.6 3.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GBG92144.1 - 1.7e-07 31.8 0.2 2.4e-06 28.2 0.2 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain RIO1 PF01163.22 GBG92144.1 - 0.0052 16.4 0.0 0.39 10.3 0.0 2.3 2 0 0 2 2 2 1 RIO1 family EcKinase PF02958.20 GBG92144.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase SpoIIIAH PF12685.7 GBG92145.1 - 0.0013 18.6 3.2 0.0014 18.5 3.2 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein Mpp10 PF04006.12 GBG92145.1 - 0.0025 16.3 15.1 0.0032 16.0 15.1 1.0 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 GBG92145.1 - 0.0046 16.4 12.0 0.0052 16.2 12.0 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 GBG92145.1 - 0.0052 15.1 15.8 0.0055 15.0 15.8 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 GBG92145.1 - 0.0061 14.9 8.3 0.0061 14.9 8.3 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GBG92145.1 - 0.0062 16.0 14.9 0.0069 15.9 14.9 1.1 1 0 0 1 1 1 1 SDA1 NPR3 PF03666.13 GBG92145.1 - 0.027 13.3 3.6 0.032 13.0 3.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spore_coat_CotO PF14153.6 GBG92145.1 - 0.034 14.1 4.6 0.041 13.8 4.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 GBG92145.1 - 0.11 11.2 0.8 0.13 11.1 0.8 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 GBG92145.1 - 0.18 10.6 5.2 0.23 10.2 5.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 GBG92145.1 - 0.21 10.8 2.1 0.23 10.7 2.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_3_Rpc31 PF11705.8 GBG92145.1 - 0.22 11.7 23.6 0.31 11.2 23.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RNA_polI_A34 PF08208.11 GBG92145.1 - 0.31 11.1 12.5 0.35 10.9 12.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DNA_pol_phi PF04931.13 GBG92145.1 - 1 7.4 19.7 1.1 7.3 19.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC27 PF09507.10 GBG92145.1 - 1.4 8.2 14.0 1.7 8.0 14.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2201_N PF13203.6 GBG92145.1 - 1.7 8.2 6.0 2.4 7.7 6.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4746 PF15928.5 GBG92145.1 - 1.8 7.9 14.5 2.3 7.5 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDRGK PF09756.9 GBG92145.1 - 1.8 8.1 16.9 2.9 7.4 16.9 1.3 1 0 0 1 1 1 0 DDRGK domain Vfa1 PF08432.10 GBG92145.1 - 1.8 8.9 8.8 2.8 8.2 8.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.14 GBG92145.1 - 1.9 8.9 6.0 3.2 8.2 6.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4337 PF14235.6 GBG92145.1 - 2 8.5 3.7 2.9 8.0 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) NOA36 PF06524.12 GBG92145.1 - 2.1 7.6 20.3 3.1 7.0 20.3 1.2 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 GBG92145.1 - 2.5 8.0 14.5 4.2 7.3 14.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain V_ATPase_I PF01496.19 GBG92145.1 - 2.8 5.7 5.2 3.5 5.4 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAF PF15715.5 GBG92145.1 - 2.9 8.5 13.9 5.2 7.7 13.9 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain RRN3 PF05327.11 GBG92145.1 - 4.1 5.8 8.1 4 5.9 8.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 GBG92145.1 - 4.7 6.3 13.8 5.9 5.9 13.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein AAA_11 PF13086.6 GBG92146.1 - 3.3e-10 40.2 0.1 4.9e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG92146.1 - 0.00015 22.1 0.1 0.00024 21.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GBG92146.1 - 0.00028 20.7 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GBG92146.1 - 0.028 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 GBG92146.1 - 0.035 14.5 0.1 0.074 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 GBG92146.1 - 0.11 12.9 0.3 0.21 12.0 0.3 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GBG92146.1 - 0.14 12.2 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GBG92146.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 GBG92146.1 - 0.18 11.0 0.1 0.26 10.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RVT_1 PF00078.27 GBG92147.1 - 1.1e-28 100.3 0.2 2.5e-28 99.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92147.1 - 2e-26 91.9 0.0 7e-26 90.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92147.1 - 1.7e-24 86.1 0.0 3.6e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92147.1 - 1.3e-19 70.0 0.2 2.6e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92147.1 - 1.3e-08 35.0 0.1 9.2e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG92147.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG92148.1 - 0.11 12.7 0.3 0.18 12.0 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle CDH1_2_SANT_HL1 PF18375.1 GBG92148.1 - 0.98 10.1 4.7 4.2 8.1 0.1 2.7 2 1 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 ANAPC15 PF15243.6 GBG92149.1 - 0.034 14.5 4.1 0.05 14.0 4.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 AAA_12 PF13087.6 GBG92149.1 - 0.088 12.4 0.3 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 AAA domain NOA36 PF06524.12 GBG92149.1 - 0.17 11.2 7.0 0.21 10.9 7.0 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 GBG92149.1 - 0.18 11.8 2.9 0.25 11.4 2.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_repr_REX1B PF14966.6 GBG92150.1 - 5.1e-27 94.4 0.9 6.5e-18 65.2 0.1 3.5 3 0 0 3 3 3 2 DNA repair REX1-B GCIP PF13324.6 GBG92150.1 - 0.34 10.5 2.0 0.68 9.5 0.1 2.0 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting AF-4 PF05110.13 GBG92150.1 - 4.8 5.1 10.8 6.9 4.6 10.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pkinase_Tyr PF07714.17 GBG92151.1 - 9.4e-33 113.6 0.0 5.5e-25 88.1 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 GBG92151.1 - 7e-32 110.8 0.0 2e-10 40.5 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Insulin_TMD PF17870.1 GBG92151.1 - 0.045 13.8 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment APH PF01636.23 GBG92151.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family TraG-D_C PF12696.7 GBG92151.1 - 0.68 9.9 12.9 0.42 10.6 2.9 2.8 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG PRIMA1 PF16101.5 GBG92151.1 - 3.1 7.8 9.0 6.2 6.9 2.0 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RT_RNaseH_2 PF17919.1 GBG92154.1 - 2.7e-18 65.8 0.0 5.9e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92154.1 - 9.5e-16 58.0 0.0 2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92154.1 - 1.3e-13 50.8 0.2 3.6e-13 49.4 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG92154.1 - 6.6e-08 32.3 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG92154.1 - 2.7e-07 30.8 0.0 6.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG92154.1 - 0.0062 16.7 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Pkinase_Tyr PF07714.17 GBG92155.1 - 9.5e-38 129.9 0.0 2.3e-37 128.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG92155.1 - 1.9e-34 119.3 0.0 2.7e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG92155.1 - 0.0092 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF659 PF04937.15 GBG92157.1 - 7.8e-16 58.3 0.0 1.6e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4096 PF13340.6 GBG92157.1 - 0.33 11.2 1.5 0.73 10.1 0.2 2.2 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) Macoilin PF09726.9 GBG92157.1 - 0.69 8.4 15.4 0.88 8.1 15.4 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 GBG92157.1 - 4.2 6.1 19.1 5.8 5.6 19.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.25 GBG92158.1 - 5.2e-18 65.4 0.0 2e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG92158.1 - 5.1e-13 48.9 0.0 3.4e-12 46.2 0.0 1.8 1 1 1 2 2 2 2 Protein tyrosine kinase TBCA PF02970.16 GBG92159.1 - 0.014 15.7 2.3 0.014 15.7 2.3 2.9 3 1 0 3 3 3 0 Tubulin binding cofactor A Pkinase PF00069.25 GBG92161.1 - 1.3e-21 77.2 0.0 1.9e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG92161.1 - 6.3e-19 68.3 0.0 9.6e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG92161.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DNA_pol_phi PF04931.13 GBG92162.1 - 1.4 7.0 15.2 1.6 6.7 15.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 GBG92163.1 - 4.4e-38 131.2 0.0 6.5e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG92163.1 - 1.7e-37 129.1 0.0 4.5e-37 127.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GBG92163.1 - 0.015 15.2 0.0 0.045 13.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family PIF1 PF05970.14 GBG92165.1 - 4.2e-24 85.4 0.0 6.7e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase DTHCT PF08070.11 GBG92165.1 - 0.083 13.6 3.5 1 10.1 0.8 2.3 2 0 0 2 2 2 0 DTHCT (NUC029) region RVT_1 PF00078.27 GBG92168.1 - 2.9e-35 121.8 0.0 5.2e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92168.1 - 2.1e-27 95.1 0.0 5.6e-27 93.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92168.1 - 6.7e-19 68.1 0.0 1.9e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase IL11 PF07400.11 GBG92168.1 - 0.021 14.5 0.3 0.058 13.0 0.3 1.7 1 0 0 1 1 1 0 Interleukin 11 MREG PF15812.5 GBG92168.1 - 0.032 14.6 1.0 0.088 13.1 1.0 1.7 1 0 0 1 1 1 0 Melanoregulin Nup54_57_C PF18570.1 GBG92168.1 - 0.1 12.2 1.5 0.36 10.5 1.5 1.9 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain NPV_P10 PF05531.12 GBG92168.1 - 1 9.9 3.4 1.4 9.4 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Retrotrans_gag PF03732.17 GBG92169.1 - 0.018 15.3 0.0 0.051 13.9 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG92170.1 - 1.5e-32 111.6 0.0 1.2e-16 60.6 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92170.1 - 3.8e-31 108.3 0.1 6.7e-31 107.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92170.1 - 1.6e-25 89.4 0.0 5.1e-25 87.8 0.0 1.9 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase FAA_hydrolase PF01557.18 GBG92171.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family YL1 PF05764.13 GBG92172.1 - 0.022 14.9 23.9 0.035 14.2 23.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GBG92172.1 - 0.14 11.5 27.5 0.19 11.1 27.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG92172.1 - 0.2 11.1 24.8 0.27 10.6 24.8 1.2 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 GBG92172.1 - 0.75 9.7 11.0 1.9 8.4 11.0 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 GBG92172.1 - 2.4 6.3 19.5 3.4 5.8 19.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG92172.1 - 2.5 7.6 13.7 3.5 7.1 13.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Vfa1 PF08432.10 GBG92172.1 - 2.5 8.4 12.0 4.3 7.6 12.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 GBG92172.1 - 2.7 6.1 28.6 3.6 5.7 28.6 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GBG92172.1 - 5.4 5.5 24.5 1.4 7.5 20.9 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.15 GBG92172.1 - 6.4 5.4 7.3 7.1 5.3 7.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 GBG92172.1 - 8.3 5.3 6.2 13 4.7 6.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RVT_1 PF00078.27 GBG92173.1 - 8.1e-31 107.3 0.0 1.4e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92173.1 - 4.3e-14 52.4 0.0 1.1e-13 51.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92173.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-CCHC_5 PF14787.6 GBG92176.1 - 0.0019 17.9 1.5 0.0036 17.0 1.5 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger EspA PF03433.13 GBG92176.1 - 0.0038 17.1 0.5 0.013 15.3 0.4 1.8 1 1 0 1 1 1 1 EspA-like secreted protein SPOUT_MTase_2 PF14419.6 GBG92176.1 - 0.0099 15.3 0.1 0.021 14.2 0.1 1.5 1 0 0 1 1 1 1 AF2226-like SPOUT RNA Methylase fused to THUMP PriC PF07445.12 GBG92176.1 - 0.46 10.4 6.5 0.052 13.5 1.5 1.9 1 1 1 2 2 2 0 Primosomal replication protein priC E2F_CC-MB PF16421.5 GBG92177.1 - 9.1e-32 109.3 0.1 1.5e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain Co_AT_N PF12557.8 GBG92178.1 - 0.02 14.8 4.7 0.073 13.0 4.7 2.1 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal DUF2052 PF09747.9 GBG92181.1 - 0.025 14.7 5.0 0.025 14.7 5.0 4.6 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SPRY PF00622.28 GBG92182.1 - 2.9e-09 37.1 0.1 6.6e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 SPRY domain FAM53 PF15242.6 GBG92182.1 - 0.062 13.1 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Family of FAM53 HsdM_N PF12161.8 GBG92182.1 - 0.31 11.7 0.8 55 4.4 0.0 2.5 2 0 0 2 2 2 0 HsdM N-terminal domain SGP PF17228.2 GBG92182.1 - 7.4 7.5 7.9 0.5 11.3 0.9 2.5 2 1 0 2 2 2 0 Sulphur globule protein DBD_Tnp_Hermes PF10683.9 GBG92184.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain SPRY PF00622.28 GBG92185.1 - 1.1e-10 41.7 6.6 6.6e-09 35.9 0.1 3.0 3 0 0 3 3 3 2 SPRY domain FAM53 PF15242.6 GBG92185.1 - 0.35 10.6 2.3 0.22 11.3 0.2 1.7 2 0 0 2 2 2 0 Family of FAM53 SRP-alpha_N PF04086.13 GBG92186.1 - 0.19 11.6 11.5 0.31 10.9 11.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 GBG92186.1 - 0.85 8.3 3.4 1.2 7.9 3.4 1.1 1 0 0 1 1 1 0 Presenilin zf-CCHC_2 PF13696.6 GBG92186.1 - 1.6 8.6 4.2 2.7 7.9 4.2 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG92188.1 - 5.5e-19 68.0 0.0 1.8e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92188.1 - 3.1e-17 62.8 0.0 3.9e-16 59.2 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92188.1 - 1.2e-07 31.4 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG92189.1 - 9.8e-24 84.1 0.1 2e-23 83.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92189.1 - 9.9e-12 44.8 0.0 2.7e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG92189.1 - 5.3e-10 39.0 0.0 1.4e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 GBG92189.1 - 0.0012 19.2 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG92189.1 - 0.0063 16.8 0.0 0.048 13.9 0.0 2.5 1 0 0 1 1 1 1 Retrotransposon gag protein Laminin_II PF06009.12 GBG92189.1 - 0.0084 16.1 0.8 0.03 14.4 0.9 1.8 2 0 0 2 2 2 1 Laminin Domain II Lys-AminoMut_A PF09043.11 GBG92189.1 - 0.071 11.6 2.9 0.028 12.9 0.3 1.5 2 0 0 2 2 2 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit HEAT PF02985.22 GBG92191.1 - 0.17 12.2 1.0 5.6 7.5 0.1 3.2 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 GBG92191.1 - 0.31 11.6 2.7 5.1 7.7 0.0 4.0 3 0 0 3 3 3 0 HEAT-like repeat DUF659 PF04937.15 GBG92192.1 - 8.9e-36 123.0 0.0 1.9e-35 121.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GREB1 PF15782.5 GBG92192.1 - 0.18 8.9 31.9 0.29 8.2 31.9 1.4 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RT_RNaseH_2 PF17919.1 GBG92193.1 - 6.9e-20 71.0 0.0 1.2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92193.1 - 4e-19 68.8 0.0 8.6e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92193.1 - 2.5e-05 24.4 0.0 8.1e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GBG92193.1 - 0.064 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain rve PF00665.26 GBG92194.1 - 3.3e-14 53.1 0.0 7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GBG92194.1 - 0.00067 19.4 0.0 0.0022 17.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG92194.1 - 0.14 12.8 0.0 0.42 11.2 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Trp_syntA PF00290.20 GBG92196.1 - 0.0045 15.9 0.1 0.014 14.3 0.0 1.7 2 0 0 2 2 2 1 Tryptophan synthase alpha chain Lipin_mid PF16876.5 GBG92196.1 - 0.012 15.7 1.5 0.041 14.0 0.0 2.3 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain APP_E2 PF12925.7 GBG92197.1 - 0.013 15.3 1.0 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein DUF1090 PF06476.12 GBG92197.1 - 0.064 13.4 2.0 7.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF3192 PF11399.8 GBG92197.1 - 0.068 13.1 0.2 2.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) TOBE_2 PF08402.10 GBG92197.1 - 0.094 12.9 0.1 16 5.7 0.0 2.8 2 0 0 2 2 2 0 TOBE domain Yos9_DD PF17880.1 GBG92197.1 - 0.18 12.0 0.0 23 5.1 0.0 2.2 2 0 0 2 2 2 0 Yos9 dimerzation domain DDE_Tnp_4 PF13359.6 GBG92200.1 - 5.1e-21 75.0 0.0 7.6e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92200.1 - 2.2e-08 34.0 0.0 5.1e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein Myb_DNA-bind_4 PF13837.6 GBG92200.1 - 1.9e-05 25.0 0.2 3e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Flp1_like PF16982.5 GBG92201.1 - 0.087 12.2 3.2 0.24 10.8 3.2 1.7 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain BUD22 PF09073.10 GBG92203.1 - 0.13 11.6 10.0 0.15 11.4 10.0 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG92203.1 - 0.19 9.9 17.0 0.29 9.3 17.0 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GBG92203.1 - 0.2 9.7 21.1 0.26 9.4 21.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi UPF0181 PF03701.14 GBG92203.1 - 0.23 11.1 0.3 29 4.4 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0181) CDC45 PF02724.14 GBG92203.1 - 0.26 9.5 10.8 0.32 9.2 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GBG92203.1 - 0.45 9.9 15.0 0.67 9.3 15.0 1.2 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 GBG92203.1 - 3.3 6.8 9.4 5 6.2 9.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit N6_N4_Mtase PF01555.18 GBG92204.1 - 7.4e-10 38.9 0.0 1.2e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 DNA methylase zf-LITAF-like PF10601.9 GBG92207.1 - 0.11 12.7 2.2 41 4.5 0.0 4.8 6 0 0 6 6 6 0 LITAF-like zinc ribbon domain DUF2157 PF09925.9 GBG92207.1 - 0.43 10.4 4.0 1.3 8.8 0.4 3.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF898 PF05987.13 GBG92207.1 - 1.4 7.9 25.0 1 8.3 4.4 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF898) MIG-14_Wnt-bd PF06664.12 GBG92207.1 - 4.9 6.3 13.2 7.2 5.7 5.9 2.7 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion DHHC PF01529.20 GBG92207.1 - 9.3 6.4 12.2 1.6 8.8 0.8 3.3 2 1 1 3 3 3 0 DHHC palmitoyltransferase HIP1_clath_bdg PF16515.5 GBG92209.1 - 0.0029 18.2 4.0 0.0029 18.2 4.0 3.5 3 1 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 LMBR1 PF04791.16 GBG92209.1 - 0.25 10.2 2.9 0.27 10.1 2.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 GBG92209.1 - 0.45 9.0 14.9 0.55 8.7 14.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 GBG92209.1 - 1.4 9.0 5.4 5.2 7.1 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HAD_2 PF13419.6 GBG92210.1 - 2.9e-06 27.5 0.0 4.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GBG92210.1 - 0.00013 21.9 0.0 0.00099 19.1 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GBG92210.1 - 0.064 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase bZIP_Maf PF03131.17 GBG92210.1 - 0.4 11.2 4.4 0.53 10.8 0.3 2.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Fasciclin PF02469.22 GBG92211.1 - 3.5e-14 53.1 0.0 6.2e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain Branch PF02485.21 GBG92212.1 - 1.2e-51 175.6 0.3 1.5e-51 175.3 0.3 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Sulphotransf PF09037.10 GBG92214.1 - 0.027 14.0 0.0 0.82 9.2 0.0 2.2 1 1 1 2 2 2 0 Stf0 sulphotransferase DUF812 PF05667.11 GBG92215.1 - 1.5 7.6 34.8 2.8 6.7 34.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) EMP24_GP25L PF01105.24 GBG92215.1 - 6.1 6.7 13.2 0.82 9.6 2.9 2.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD rve PF00665.26 GBG92217.1 - 5.2e-09 36.3 0.0 8.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG92218.1 - 1.9e-22 79.2 0.0 5.9e-22 77.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92218.1 - 1.2e-21 77.0 0.1 3.1e-20 72.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92218.1 - 1.9e-18 66.3 0.2 3.6e-18 65.4 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92218.1 - 1.5e-08 34.9 0.2 7.8e-08 32.5 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain Retrotrans_gag PF03732.17 GBG92218.1 - 0.00098 19.4 0.8 0.005 17.1 0.2 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG92218.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DUF659 PF04937.15 GBG92219.1 - 2.3e-11 43.8 0.0 3.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92219.1 - 5.3e-06 26.1 0.2 1e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Plavaka PF18759.1 GBG92220.1 - 5.2e-18 65.4 0.1 1.2e-17 64.2 0.1 1.5 1 0 0 1 1 1 1 Plavaka transposase TFIIA PF03153.13 GBG92220.1 - 0.0044 17.1 14.6 0.0085 16.1 14.6 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RVT_1 PF00078.27 GBG92221.1 - 2.1e-29 102.6 0.1 3.1e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92221.1 - 5.5e-17 61.6 0.0 1.8e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92221.1 - 9.9e-05 22.6 0.0 0.00025 21.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase CorA PF01544.18 GBG92222.1 - 0.0076 15.6 1.1 0.016 14.5 1.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Herpes_BLRF2 PF05812.12 GBG92222.1 - 0.033 14.3 5.9 0.097 12.8 0.4 3.3 1 1 2 3 3 3 0 Herpesvirus BLRF2 protein DUF2205 PF10224.9 GBG92222.1 - 0.035 14.1 0.3 0.035 14.1 0.3 3.5 2 1 1 3 3 3 0 Short coiled-coil protein DUF4407 PF14362.6 GBG92222.1 - 0.043 13.2 13.8 0.74 9.1 10.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF484 PF04340.12 GBG92222.1 - 0.051 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF484 LMBR1 PF04791.16 GBG92222.1 - 0.27 10.1 1.1 5.1 5.9 0.0 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein PAC1 PF16094.5 GBG92222.1 - 0.3 10.2 2.7 0.48 9.5 2.7 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Laminin_II PF06009.12 GBG92222.1 - 0.52 10.3 0.1 0.52 10.3 0.1 2.9 3 1 1 4 4 4 0 Laminin Domain II FlxA PF14282.6 GBG92222.1 - 2.6 8.1 12.9 12 6.0 0.0 4.3 3 2 0 4 4 4 0 FlxA-like protein PriCT_1 PF08708.11 GBG92223.1 - 0.084 12.6 0.3 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) RVT_1 PF00078.27 GBG92224.1 - 6.8e-22 78.1 0.1 9.1e-22 77.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Slu7 PF11708.8 GBG92225.1 - 6.1e-93 311.5 14.0 6.1e-93 311.5 14.0 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 GBG92225.1 - 0.096 12.4 0.5 0.23 11.2 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Microtub_bind PF13931.6 GBG92225.1 - 1.2 9.5 8.8 0.17 12.3 2.1 2.6 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding DEAD PF00270.29 GBG92226.1 - 3.2e-47 160.6 0.1 8.6e-47 159.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.6 GBG92226.1 - 1.8e-20 72.9 0.9 3.3e-20 72.1 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 GBG92226.1 - 1.1e-10 41.9 1.9 2.8e-09 37.3 1.2 3.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GBG92226.1 - 1.3e-05 25.3 0.1 5.2e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 GBG92227.1 - 6e-08 32.4 4.0 9.9e-08 31.7 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92227.1 - 0.00039 20.2 1.1 0.00063 19.5 1.1 1.3 1 0 0 1 1 1 1 Zinc knuckle MRP-S31 PF15433.6 GBG92227.1 - 0.52 9.9 14.3 0.86 9.2 14.3 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Ferlin_C PF16165.5 GBG92227.1 - 0.95 9.4 5.9 2.3 8.2 5.6 1.7 2 0 0 2 2 2 0 Ferlin C-terminus Atg14 PF10186.9 GBG92227.1 - 3.9 6.5 9.4 6.1 5.8 9.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-CCHC PF00098.23 GBG92228.1 - 1.8e-08 34.0 4.0 3.1e-08 33.3 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92228.1 - 0.00012 21.8 1.1 0.0002 21.1 1.1 1.3 1 0 0 1 1 1 1 Zinc knuckle MRP-S31 PF15433.6 GBG92228.1 - 0.078 12.6 14.4 0.098 12.3 14.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PA26 PF04636.13 GBG92228.1 - 0.14 11.0 5.0 0.16 10.9 5.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) zf-CCHC_4 PF14392.6 GBG92228.1 - 0.17 11.7 1.0 0.34 10.7 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Perilipin PF03036.16 GBG92228.1 - 0.89 8.5 8.6 1 8.3 8.6 1.2 1 0 0 1 1 1 0 Perilipin family Atg14 PF10186.9 GBG92228.1 - 1 8.4 10.1 1.3 8.0 10.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RVT_1 PF00078.27 GBG92229.1 - 7.3e-05 22.4 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 GBG92230.1 - 1.9e-21 76.4 0.0 4.2e-21 75.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92230.1 - 9e-10 38.5 0.0 2.2e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92230.1 - 0.00024 20.8 0.1 0.0053 16.4 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG92230.1 - 0.0043 17.4 0.1 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain MccV PF17508.2 GBG92230.1 - 0.18 12.4 0.1 0.35 11.4 0.1 1.4 1 0 0 1 1 1 0 Microcin V bacteriocin SPT2 PF08243.11 GBG92232.1 - 0.19 12.3 5.5 0.28 11.7 2.0 2.6 2 0 0 2 2 2 0 SPT2 chromatin protein zinc_ribbon_10 PF10058.9 GBG92235.1 - 2.1e-17 62.6 1.1 3.6e-17 61.8 1.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 GBG92235.1 - 0.02 14.3 0.2 0.04 13.4 0.2 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com DUF2663 PF10864.8 GBG92235.1 - 0.23 11.9 1.5 0.4 11.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) MCU PF04678.13 GBG92236.1 - 6.7e-42 143.6 0.3 1.1e-41 142.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter COR PF16095.5 GBG92236.1 - 0.045 13.6 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain RVT_1 PF00078.27 GBG92238.1 - 5.5e-35 120.9 0.1 1e-34 120.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92238.1 - 5.9e-29 100.0 0.0 2.6e-28 98.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92238.1 - 1.6e-28 99.0 0.0 3.5e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2950 PF11453.8 GBG92239.1 - 0.0072 15.6 5.5 0.009 15.3 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2950) DUF3629 PF12302.8 GBG92239.1 - 0.074 12.5 9.2 0.1 12.0 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) PA26 PF04636.13 GBG92239.1 - 0.22 10.4 10.5 0.24 10.3 10.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3138 PF11336.8 GBG92239.1 - 0.45 9.1 2.2 0.54 8.8 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF87 PF01935.17 GBG92239.1 - 2.5 8.1 6.3 3.2 7.8 6.3 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain Chromo PF00385.24 GBG92240.1 - 1.4e-05 24.9 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG92241.1 - 3.1e-16 59.2 0.0 7.7e-14 51.6 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG92241.1 - 2.3e-10 40.2 0.0 4.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG92241.1 - 3.7e-10 40.0 0.0 1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG92241.1 - 2.7e-09 36.9 0.1 5.5e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92241.1 - 1.8e-06 28.2 0.0 6.9e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Hormone_3 PF00159.18 GBG92241.1 - 0.014 15.5 0.2 0.014 15.5 0.2 3.3 3 0 0 3 3 3 0 Pancreatic hormone peptide Na_H_Exchanger PF00999.21 GBG92242.1 - 1.1e-64 218.6 38.4 1.4e-64 218.3 38.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pro_CA PF00484.19 GBG92246.1 - 0.23 11.8 4.8 0.061 13.6 0.6 2.2 2 0 0 2 2 2 0 Carbonic anhydrase zf-CCHC PF00098.23 GBG92246.1 - 0.61 10.3 8.6 0.21 11.7 5.2 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92246.1 - 2.2 8.2 5.6 4.4 7.2 5.6 1.5 1 0 0 1 1 1 0 Zinc knuckle NTP_transf_2 PF01909.23 GBG92247.1 - 0.00055 20.2 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 GBG92247.1 - 0.0028 17.8 0.3 0.025 14.8 0.3 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase Nrap_D5 PF17406.2 GBG92247.1 - 0.069 12.9 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 RT_RNaseH_2 PF17919.1 GBG92248.1 - 7.2e-34 115.8 0.0 1.4e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92248.1 - 6.2e-30 103.6 0.4 1.5e-29 102.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92248.1 - 2.5e-22 79.5 0.0 4.8e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG92248.1 - 0.025 14.7 0.0 0.074 13.2 0.0 1.8 2 0 0 2 2 2 0 Integrase zinc binding domain SpvB PF03534.13 GBG92248.1 - 0.1 11.8 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein Phage_GPO PF05929.11 GBG92248.1 - 0.81 9.2 6.4 0.66 9.6 0.0 2.7 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4140 PF13600.6 GBG92248.1 - 2.5 8.6 6.2 36 4.9 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) RT_RNaseH_2 PF17919.1 GBG92249.1 - 3.3e-11 43.1 0.6 1.3e-10 41.2 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92249.1 - 0.00029 20.4 0.1 0.0005 19.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PNMA PF14893.6 GBG92249.1 - 0.061 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 PNMA RT_RNaseH PF17917.1 GBG92249.1 - 0.089 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RasGEF_N PF00618.20 GBG92249.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 RasGEF N-terminal motif Retrotrans_gag PF03732.17 GBG92250.1 - 0.0053 17.0 0.4 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 GBG92251.1 - 1.1e-55 185.9 0.0 9.1e-32 109.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92251.1 - 1.5e-54 184.9 0.7 1.7e-28 99.6 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92251.1 - 2.5e-44 149.9 0.0 3.5e-21 75.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92251.1 - 2.8e-38 129.8 1.4 1e-18 67.2 0.1 2.5 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 GBG92251.1 - 1.4e-15 57.5 0.3 8e-15 55.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG92251.1 - 9e-05 22.6 0.5 0.03 14.5 0.0 2.9 2 0 0 2 2 2 2 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG92251.1 - 0.12 12.6 0.0 0.51 10.6 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein Astro_capsid_p PF12226.8 GBG92253.1 - 0.011 14.9 6.9 0.014 14.6 6.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Myc_N PF01056.18 GBG92253.1 - 0.27 11.1 7.1 0.43 10.4 7.1 1.3 1 1 0 1 1 1 0 Myc amino-terminal region Iron_permease PF04120.12 GBG92253.1 - 0.71 9.7 2.7 6.4 6.6 0.1 2.3 1 1 1 2 2 2 0 Low affinity iron permease LAT PF15234.6 GBG92253.1 - 4.1 7.1 7.7 6.9 6.3 7.7 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells RT_RNaseH_2 PF17919.1 GBG92254.1 - 4.1e-33 113.4 0.0 7.4e-33 112.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92254.1 - 3.9e-30 104.2 0.1 7.5e-30 103.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92254.1 - 2.3e-19 69.2 0.3 6.3e-19 67.8 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG92254.1 - 4.1e-15 56.0 0.0 1.3e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Rap_GAP PF02145.15 GBG92254.1 - 0.12 12.0 0.1 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Rap/ran-GAP RVT_1 PF00078.27 GBG92254.1 - 0.15 11.6 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2408 PF10303.9 GBG92255.1 - 0.04 14.5 1.0 0.68 10.5 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Retrotrans_gag PF03732.17 GBG92255.1 - 0.13 12.6 3.0 0.94 9.8 1.7 2.8 2 1 0 2 2 2 0 Retrotransposon gag protein Ribosomal_60s PF00428.19 GBG92255.1 - 1.5 9.5 4.9 1 10.0 0.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF659 PF04937.15 GBG92256.1 - 3.8e-24 85.3 0.0 7e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4604 PF15377.6 GBG92257.1 - 0.0066 16.9 27.1 0.0066 16.9 27.1 3.5 1 1 2 3 3 3 1 Domain of unknown function (DUF4604) ETRAMP PF09716.10 GBG92257.1 - 0.04 14.0 0.7 0.04 14.0 0.7 3.4 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) BSP_II PF05432.11 GBG92257.1 - 1.2 8.8 53.1 0.066 12.9 24.5 3.3 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) Mitofilin PF09731.9 GBG92257.1 - 6.4 5.5 52.2 0.14 11.0 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein zf-CCHC PF00098.23 GBG92259.1 - 2.8e-05 24.0 1.7 7.2e-05 22.7 1.7 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF3138 PF11336.8 GBG92259.1 - 0.2 10.2 0.1 0.31 9.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Pkinase_Tyr PF07714.17 GBG92260.1 - 2.6e-38 131.8 0.0 4.1e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG92260.1 - 3.8e-36 124.8 0.0 6.3e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG92260.1 - 0.0077 16.2 3.0 0.38 10.6 0.4 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Na_trans_assoc PF06512.13 GBG92260.1 - 0.016 15.5 9.5 0.031 14.6 9.5 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 GBG92260.1 - 0.048 11.9 19.3 0.066 11.4 19.3 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG92260.1 - 0.1 11.9 15.0 0.17 11.2 15.0 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG92260.1 - 0.16 11.4 16.2 0.23 10.8 16.2 1.2 1 0 0 1 1 1 0 SDA1 GEMIN8 PF15348.6 GBG92260.1 - 0.86 9.9 7.0 1.7 8.9 7.0 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Pox_Ag35 PF03286.14 GBG92260.1 - 1.5 8.6 14.4 2.7 7.7 14.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.13 GBG92260.1 - 2.5 6.8 8.0 3.5 6.3 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TRAP_alpha PF03896.16 GBG92260.1 - 7.9 5.6 8.8 14 4.8 8.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 GBG92260.1 - 9.8 4.8 7.0 16 4.2 7.0 1.2 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 GBG92261.1 - 1.1e-17 64.3 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92261.1 - 4.4e-14 52.3 0.0 8.7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92261.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG92261.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG92261.1 - 0.033 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Na_trans_assoc PF06512.13 GBG92261.1 - 2.7 8.2 12.5 5.3 7.3 12.5 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Pkinase_Tyr PF07714.17 GBG92262.1 - 3e-40 138.1 0.0 9.7e-40 136.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG92262.1 - 1.1e-38 133.2 0.0 1.6e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PBP_N PF17093.5 GBG92262.1 - 0.0072 16.6 0.0 6.4 7.0 0.0 2.4 2 0 0 2 2 2 2 Penicillin-binding protein N-terminus APH PF01636.23 GBG92262.1 - 0.035 14.0 1.3 0.14 12.0 0.3 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 GBG92262.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RVT_1 PF00078.27 GBG92263.1 - 1.4e-22 80.3 0.0 2.4e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92263.1 - 7e-20 71.3 0.0 1.4e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92263.1 - 3.3e-14 52.7 0.1 1.5e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG92263.1 - 1.3e-10 41.2 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92263.1 - 2e-05 24.7 0.1 7.7e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG92263.1 - 0.016 15.4 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger WD40 PF00400.32 GBG92264.1 - 5.9e-26 90.2 12.5 5.9e-06 26.9 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG92264.1 - 1.8e-09 37.8 0.0 0.0044 17.3 0.0 5.0 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4934 PF16288.5 GBG92264.1 - 0.011 15.7 0.0 4.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4934) RRM_1 PF00076.22 GBG92265.1 - 4.9e-49 164.0 0.1 8.1e-16 57.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG92265.1 - 1.3e-12 47.6 0.0 0.0013 18.8 0.0 3.6 3 2 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 GBG92265.1 - 9.2e-10 38.4 0.1 0.0014 18.6 0.0 3.3 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 GBG92265.1 - 1.6e-05 25.2 0.1 8.4 6.6 0.0 4.3 3 2 2 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter RL PF17797.1 GBG92265.1 - 0.002 18.0 0.0 10 6.2 0.0 3.3 3 0 0 3 3 3 1 RL domain DUF4140 PF13600.6 GBG92265.1 - 0.0084 16.5 0.0 0.15 12.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF4651 PF15513.6 GBG92265.1 - 0.015 15.1 0.0 0.45 10.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4651) Coprogen_oxidas PF01218.18 GBG92265.1 - 0.3 9.8 1.4 0.56 8.9 0.0 2.0 3 0 0 3 3 3 0 Coproporphyrinogen III oxidase Dimer_Tnp_hAT PF05699.14 GBG92266.1 - 0.15 11.9 1.0 0.26 11.1 1.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Syja_N PF02383.18 GBG92268.1 - 7.7e-38 130.6 0.0 1.4e-37 129.8 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain WW PF00397.26 GBG92268.1 - 2.6e-12 46.6 0.3 4.9e-12 45.7 0.3 1.5 1 0 0 1 1 1 1 WW domain Presenilin PF01080.17 GBG92269.1 - 0.31 9.8 5.8 0.44 9.3 5.8 1.3 1 0 0 1 1 1 0 Presenilin CBM_4_9 PF02018.17 GBG92270.1 - 0.00014 22.1 0.0 0.0033 17.7 0.0 2.4 1 1 0 1 1 1 1 Carbohydrate binding domain HemeBinding_Shp PF11545.8 GBG92270.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp SUKH-4 PF14435.6 GBG92271.1 - 0.074 13.1 1.0 0.18 11.8 0.5 1.8 2 0 0 2 2 2 0 SUKH-4 immunity protein DDE_Tnp_4 PF13359.6 GBG92272.1 - 5.9e-30 104.0 0.0 1.3e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92272.1 - 3.6e-15 56.1 0.0 7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92272.1 - 2.5e-06 27.3 0.1 0.15 11.7 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain IBR PF01485.21 GBG92273.1 - 7.5e-12 45.3 2.9 7.5e-12 45.3 2.9 3.2 2 2 1 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 GBG92273.1 - 0.00054 19.9 5.6 0.00054 19.9 5.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG92273.1 - 0.0026 17.6 4.2 0.0026 17.6 4.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GBG92273.1 - 0.0027 17.5 4.1 0.0027 17.5 4.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GBG92273.1 - 0.0047 16.9 7.0 0.0047 16.9 7.0 2.8 3 0 0 3 3 3 1 zinc-RING finger domain Helo_like_N PF17111.5 GBG92273.1 - 0.53 9.6 3.4 0.49 9.7 1.4 1.9 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins zf-RING_2 PF13639.6 GBG92273.1 - 1.8 9.0 18.9 0.22 11.9 8.3 2.7 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 GBG92273.1 - 5.9 7.1 16.1 0.71 10.1 4.9 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING IBR PF01485.21 GBG92275.1 - 9.5e-08 32.2 13.7 9.5e-08 32.2 13.7 2.8 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain HIP1_clath_bdg PF16515.5 GBG92275.1 - 0.014 16.0 2.6 0.014 16.0 2.6 4.6 6 0 0 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Retrotrans_gag PF03732.17 GBG92275.1 - 0.02 15.2 1.8 0.18 12.1 0.0 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein USP8_interact PF08941.10 GBG92275.1 - 0.16 11.7 1.8 3.5 7.4 0.0 3.1 3 0 0 3 3 3 0 USP8 interacting zf-C3HC4 PF00097.25 GBG92275.1 - 0.68 9.8 15.2 3.7 7.5 15.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GRP PF07172.11 GBG92275.1 - 0.77 10.5 7.5 2.3 9.0 7.5 1.8 1 0 0 1 1 1 0 Glycine rich protein family zf-RING_4 PF14570.6 GBG92275.1 - 3 7.7 12.2 13 5.6 12.2 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RT_RNaseH_2 PF17919.1 GBG92276.1 - 8e-91 298.6 0.8 2.7e-33 114.0 0.0 4.6 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92276.1 - 2.1e-71 236.9 0.6 4.3e-29 100.9 0.0 4.2 4 0 0 4 4 4 3 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92276.1 - 8.9e-34 116.2 0.4 4.6e-15 55.9 0.0 4.2 3 0 0 3 3 3 3 Integrase core domain Integrase_H2C2 PF17921.1 GBG92276.1 - 6.1e-25 87.1 4.4 2e-13 50.2 0.3 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 GBG92276.1 - 4.6e-13 49.2 0.2 5.6e-12 45.6 0.0 2.8 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1564 PF07600.11 GBG92276.1 - 0.0014 18.3 0.0 0.6 9.8 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1564) SlyX PF04102.12 GBG92276.1 - 0.0094 16.6 1.1 0.0094 16.6 1.1 4.3 3 1 1 4 4 4 1 SlyX RVP_2 PF08284.11 GBG92276.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease rve_3 PF13683.6 GBG92276.1 - 0.044 13.6 0.2 4.9 7.0 0.0 3.0 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 GBG92276.1 - 0.059 13.6 0.0 0.44 10.8 0.0 2.5 2 0 0 2 2 2 0 H2C2 zinc finger DUF16 PF01519.16 GBG92276.1 - 0.06 13.8 0.1 0.27 11.8 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 BTB PF00651.31 GBG92278.1 - 6e-13 49.0 0.0 1.4e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF5446 PF17522.2 GBG92279.1 - 0.1 12.8 0.2 0.1 12.8 0.2 3.4 2 2 1 3 3 3 0 Family of unknown function (DUF5446) HALZ PF02183.18 GBG92279.1 - 0.34 11.2 24.0 1.9 8.8 0.1 5.6 6 1 0 6 6 6 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 GBG92279.1 - 0.35 11.3 0.1 0.35 11.3 0.1 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 GBG92279.1 - 0.42 10.4 8.7 1.6 8.5 0.3 3.2 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain ADIP PF11559.8 GBG92279.1 - 1.3 9.1 27.8 0.16 12.0 11.3 3.9 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding REV PF00424.18 GBG92280.1 - 0.043 13.8 3.7 0.33 11.0 0.2 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) MMR_HSR1 PF01926.23 GBG92281.1 - 2.1e-07 31.0 0.0 5.8e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GBG92281.1 - 0.00024 20.5 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 2 AIG1 family Septin PF00735.18 GBG92281.1 - 0.00034 20.0 0.0 0.00066 19.0 0.0 1.4 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 GBG92281.1 - 0.0006 19.8 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 GBG92281.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG92281.1 - 0.0038 17.6 0.0 0.021 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 GBG92281.1 - 0.004 16.7 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MCM PF00493.23 GBG92281.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain IIGP PF05049.13 GBG92281.1 - 0.014 14.5 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) G-alpha PF00503.20 GBG92281.1 - 0.014 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 GBG92281.1 - 0.025 15.1 0.0 0.1 13.1 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_7 PF12775.7 GBG92281.1 - 0.028 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 GBG92281.1 - 0.051 13.0 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 GBG92281.1 - 0.068 13.2 0.1 18 5.4 0.0 2.6 2 0 0 2 2 2 0 Dynamin family T2SSE PF00437.20 GBG92281.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 GBG92281.1 - 0.081 13.2 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GBG92281.1 - 0.13 11.4 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GBG92281.1 - 0.14 12.6 0.0 0.41 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GBG92281.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GBG92281.1 - 0.17 12.4 0.3 0.64 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GBG92281.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Med4 PF10018.9 GBG92281.1 - 0.23 11.1 0.8 0.5 10.0 0.8 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 SDA1 PF05285.12 GBG92282.1 - 0.92 8.9 23.7 1.2 8.5 23.7 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 GBG92282.1 - 1.1 9.4 24.2 1.5 8.8 24.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF4746 PF15928.5 GBG92282.1 - 1.1 8.6 16.5 1.4 8.3 16.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 GBG92282.1 - 1.7 6.8 17.6 2.2 6.5 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GBG92282.1 - 7.5 5.8 23.8 11 5.2 23.8 1.2 1 0 0 1 1 1 0 BUD22 Nop53 PF07767.11 GBG92283.1 - 0.23 10.8 22.6 0.37 10.1 22.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.12 GBG92283.1 - 0.44 9.9 27.4 0.62 9.4 27.4 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 GBG92283.1 - 0.99 8.9 16.5 1.7 8.1 16.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Na_trans_assoc PF06512.13 GBG92283.1 - 1.3 9.2 20.5 2.5 8.3 20.4 1.6 1 1 0 1 1 1 0 Sodium ion transport-associated DUF966 PF06136.13 GBG92283.1 - 1.5 8.5 11.4 2.6 7.7 11.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4683 PF15735.5 GBG92283.1 - 2.7 7.5 8.7 4.2 6.9 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) LAP1C PF05609.12 GBG92283.1 - 3.8 6.5 12.3 5.2 6.1 12.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 GBG92283.1 - 4.2 5.6 21.8 7.3 4.8 21.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG92283.1 - 4.2 5.5 30.3 5.8 5.0 30.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 GBG92283.1 - 5.9 6.2 21.9 12 5.2 21.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BUD22 PF09073.10 GBG92283.1 - 7 5.9 30.1 11 5.3 30.1 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GBG92283.1 - 8.5 6.0 24.5 12 5.5 24.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG92284.1 - 3.6 5.8 7.4 4.8 5.4 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase_Tyr PF07714.17 GBG92285.1 - 1.5e-31 109.7 0.0 5.6e-30 104.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG92285.1 - 5.2e-29 101.4 0.0 9.7e-29 100.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG92285.1 - 0.0035 16.2 0.0 0.0047 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GBG92285.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 GBG92286.1 - 5.7e-20 71.2 0.1 3.4e-19 68.7 0.0 2.3 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92286.1 - 5.3e-12 45.9 0.0 3.4e-11 43.3 0.0 2.5 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92286.1 - 2e-09 37.4 0.0 5.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG92286.1 - 0.0019 18.4 0.0 0.0078 16.5 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.26 GBG92287.1 - 3.2e-12 46.7 0.0 8.1e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 GBG92287.1 - 2.6e-07 30.4 0.5 2.6e-07 30.4 0.5 1.8 2 0 0 2 2 2 1 Zinc knuckle RVT_1 PF00078.27 GBG92287.1 - 5.6e-05 22.8 0.0 0.032 13.8 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 GBG92287.1 - 0.037 13.9 0.5 0.081 12.8 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle AAA_23 PF13476.6 GBG92287.1 - 0.081 13.4 2.9 5.2 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain zf-CCHC_4 PF14392.6 GBG92287.1 - 0.13 12.0 0.8 0.38 10.5 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle Anti-TRAP PF15777.5 GBG92287.1 - 0.18 11.8 0.7 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein RVT_1 PF00078.27 GBG92288.1 - 2.1e-33 115.7 0.0 3.6e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92288.1 - 3.9e-30 104.2 0.1 8.8e-30 103.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92288.1 - 4.9e-30 103.5 0.0 1.5e-29 102.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG92288.1 - 0.00025 21.3 0.1 0.0058 16.9 0.0 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein ZU5 PF00791.20 GBG92288.1 - 0.018 15.4 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 ZU5 domain CutA1 PF03091.15 GBG92288.1 - 0.027 14.3 0.3 0.13 12.1 0.3 2.2 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein RT_RNaseH PF17917.1 GBG92290.1 - 1.1e-29 102.7 0.1 2.2e-29 101.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92290.1 - 1.7e-25 89.0 0.0 3e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92290.1 - 5.2e-20 71.3 0.1 1.1e-19 70.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92290.1 - 6.4e-10 39.3 0.0 1.9e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG92290.1 - 0.00013 22.1 0.0 0.00039 20.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger SANT_DAMP1_like PF16282.5 GBG92290.1 - 0.28 11.4 5.2 3.2 8.0 0.1 2.9 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 RVT_1 PF00078.27 GBG92291.1 - 5.8e-53 179.7 0.9 1.1e-31 110.1 0.2 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92291.1 - 2.5e-50 168.6 0.0 1.6e-28 98.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92291.1 - 1.5e-32 112.0 0.0 1.6e-22 79.7 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92291.1 - 6e-16 58.3 0.1 5.1e-15 55.3 0.1 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG92291.1 - 2e-15 57.1 0.0 4.8e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG92291.1 - 8.6e-05 22.3 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG92291.1 - 0.00037 20.7 0.0 0.0017 18.5 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger CCD48 PF15799.5 GBG92291.1 - 0.012 14.0 0.7 0.018 13.4 0.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Asp_protease_2 PF13650.6 GBG92291.1 - 0.017 15.8 0.2 0.58 10.8 0.0 3.2 3 0 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG92291.1 - 0.078 13.5 0.0 1.4 9.5 0.0 3.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease eIF-1a PF01176.19 GBG92291.1 - 0.08 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Asp_protease PF09668.10 GBG92291.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease ABC_tran_CTD PF16326.5 GBG92291.1 - 0.16 12.3 1.1 1.1 9.5 1.1 2.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain RT_RNaseH_2 PF17919.1 GBG92292.1 - 7.6e-56 186.3 0.1 3.1e-31 107.4 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92292.1 - 4e-41 139.6 0.2 8.3e-29 100.0 0.3 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92292.1 - 2.4e-14 53.2 0.2 1.2e-13 51.0 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG92292.1 - 8.6e-07 29.2 0.0 2.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG92292.1 - 0.00036 20.3 0.0 0.00076 19.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92292.1 - 0.0017 18.9 0.0 0.0058 17.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease CCD48 PF15799.5 GBG92292.1 - 0.0093 14.3 3.1 0.016 13.5 3.1 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 gag-asp_proteas PF13975.6 GBG92292.1 - 0.013 16.1 0.0 0.064 13.8 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease HALZ PF02183.18 GBG92292.1 - 0.028 14.7 1.3 0.19 12.0 1.3 2.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF1687 PF07955.11 GBG92292.1 - 0.066 13.7 0.6 0.45 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) zf-H2C2 PF09337.10 GBG92292.1 - 0.07 13.4 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 H2C2 zinc finger DivIC PF04977.15 GBG92292.1 - 0.11 12.3 9.2 0.29 10.9 2.1 2.8 2 0 0 2 2 2 0 Septum formation initiator GvpL_GvpF PF06386.11 GBG92292.1 - 0.57 10.1 7.0 1.6 8.6 7.0 1.7 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Spc24 PF08286.11 GBG92292.1 - 1.8 8.9 4.2 17 5.7 0.1 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_1 PF00170.21 GBG92292.1 - 2.5 8.3 6.2 0.38 10.9 1.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor LRR_8 PF13855.6 GBG92293.1 - 0.00014 21.5 2.3 0.2 11.5 0.2 2.5 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GBG92293.1 - 0.0011 19.3 2.4 0.58 10.7 0.1 2.3 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GBG92293.1 - 0.091 12.9 1.0 0.9 9.8 0.1 2.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 GBG92293.1 - 0.099 13.3 0.7 0.56 11.0 0.3 2.3 3 0 0 3 3 3 0 Leucine Rich Repeat RT_RNaseH_2 PF17919.1 GBG92294.1 - 1.3e-34 118.2 0.1 3.8e-34 116.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92294.1 - 9.3e-31 106.2 0.0 3.4e-30 104.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92294.1 - 3e-17 62.5 0.1 6.2e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92294.1 - 1.9e-11 44.2 0.0 4.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG92294.1 - 5.9e-10 39.0 0.1 1.2e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NIF PF03031.18 GBG92294.1 - 0.043 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Presenilin PF01080.17 GBG92294.1 - 0.18 10.5 2.4 0.3 9.8 2.4 1.2 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 GBG92294.1 - 1.8 8.1 5.6 4.7 6.7 5.6 1.7 1 0 0 1 1 1 0 Virilizer, N-terminal CSRNP_N PF16019.5 GBG92294.1 - 4.4 7.2 11.1 0.27 11.1 2.6 2.7 3 0 0 3 3 3 0 Cysteine/serine-rich nuclear protein N-terminus DDE_Tnp_4 PF13359.6 GBG92297.1 - 4.7e-20 71.8 0.0 7.5e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92297.1 - 1.7e-08 34.3 0.0 3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92297.1 - 1.7e-06 27.8 1.7 1.1e-05 25.2 0.3 2.4 2 1 0 2 2 2 1 Transposase DDE domain TPT PF03151.16 GBG92298.1 - 1.1e-16 61.0 17.2 1.7e-16 60.4 17.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF659 PF04937.15 GBG92299.1 - 2.4e-06 27.5 0.0 4.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) HSP70 PF00012.20 GBG92301.1 - 1.1e-163 545.6 0.0 1.6e-163 545.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG92301.1 - 1.1e-09 37.6 0.3 2.4e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 GBG92301.1 - 0.00051 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 GBG92301.1 - 0.044 12.8 0.2 2.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain BORCS8 PF10167.9 GBG92301.1 - 0.053 13.5 0.0 0.35 10.8 0.0 2.4 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 8 HSP70 PF00012.20 GBG92302.1 - 2.7e-172 574.1 0.0 3.3e-172 573.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG92302.1 - 4.4e-12 45.5 1.3 1.7e-08 33.7 0.6 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG92302.1 - 3.5e-05 23.6 0.1 6.9e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GBG92302.1 - 0.00076 19.9 0.9 1.1 9.7 0.0 3.3 2 1 0 2 2 2 2 Cell division protein FtsA DDR PF08841.10 GBG92302.1 - 0.034 13.1 0.4 2.2 7.2 0.2 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF4879 PF16219.5 GBG92302.1 - 0.18 12.0 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4879) zf-RRN7 PF11781.8 GBG92303.1 - 0.1 12.3 1.3 0.18 11.5 1.3 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Retrotrans_gag PF03732.17 GBG92306.1 - 0.00063 20.0 0.2 0.00063 20.0 0.2 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein Herpes_BLRF2 PF05812.12 GBG92306.1 - 0.028 14.6 0.8 0.065 13.4 0.3 2.0 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Unstab_antitox PF09720.10 GBG92306.1 - 0.36 10.9 4.7 0.63 10.1 0.0 3.0 3 0 0 3 3 3 0 Putative addiction module component MscS_TM PF12794.7 GBG92306.1 - 2.8 6.7 5.3 4.9 5.9 5.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 zf-CCHC PF00098.23 GBG92308.1 - 6.4e-09 35.5 1.7 1e-08 34.9 1.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92308.1 - 0.0057 16.5 1.3 0.0085 15.9 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle Synaphin PF05835.12 GBG92308.1 - 0.011 16.0 10.3 0.011 16.0 10.3 3.3 2 1 1 3 3 3 0 Synaphin protein Mo-co_dimer PF03404.16 GBG92308.1 - 0.012 15.6 0.2 0.034 14.2 0.2 1.7 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain zf-CCHC_6 PF15288.6 GBG92308.1 - 0.05 13.5 0.2 0.15 11.9 0.2 1.9 1 0 0 1 1 1 0 Zinc knuckle Synaptonemal_3 PF15191.6 GBG92308.1 - 0.099 12.4 0.2 0.099 12.4 0.2 2.4 3 0 0 3 3 3 0 Synaptonemal complex central element protein 3 DUF3584 PF12128.8 GBG92308.1 - 0.13 9.8 36.3 0.054 11.0 24.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Rgp1 PF08737.10 GBG92308.1 - 0.28 10.3 9.4 0.025 13.8 4.6 1.5 2 0 0 2 2 2 0 Rgp1 LMBR1 PF04791.16 GBG92308.1 - 0.98 8.2 5.7 3.5 6.4 2.5 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein gag-asp_proteas PF13975.6 GBG92309.1 - 2.3e-08 34.5 0.0 4.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92309.1 - 2.5e-06 28.0 0.0 5.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92309.1 - 0.00063 19.5 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease ATE_N PF04376.13 GBG92309.1 - 0.037 14.4 0.1 0.38 11.2 0.0 2.4 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus TetR_C_9 PF14514.6 GBG92309.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-CCHC PF00098.23 GBG92309.1 - 0.43 10.7 1.9 0.97 9.6 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG92309.1 - 0.58 9.9 3.2 0.41 10.3 0.2 2.4 3 0 0 3 3 3 0 Topoisomerase I zinc-ribbon-like SPX PF03105.19 GBG92310.1 - 1.7e-13 51.3 18.0 4.4e-09 36.7 0.0 3.1 2 1 1 3 3 3 2 SPX domain HIP1_clath_bdg PF16515.5 GBG92311.1 - 6.8e-05 23.4 2.3 6.8e-05 23.4 2.3 3.2 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 GBG92311.1 - 0.073 12.4 12.7 0.94 8.8 7.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 GBG92311.1 - 0.24 11.4 1.7 19 5.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 GBG92311.1 - 0.32 11.5 4.9 0.52 10.8 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Scaffolding_pro PF11418.8 GBG92311.1 - 0.4 11.3 4.2 5.7 7.6 0.1 3.1 3 0 0 3 3 3 0 Phi29 scaffolding protein SPARC_Ca_bdg PF10591.9 GBG92311.1 - 0.74 10.2 4.6 0.37 11.1 1.7 1.9 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ADIP PF11559.8 GBG92311.1 - 0.76 9.8 18.1 0.18 11.9 2.8 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding zf-MYND PF01753.18 GBG92312.1 - 1.2e-09 38.1 8.0 1.2e-09 38.1 8.0 2.0 2 0 0 2 2 2 1 MYND finger Myb_DNA-binding PF00249.31 GBG92312.1 - 0.23 11.7 0.0 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain zf-MYND PF01753.18 GBG92313.1 - 3.1e-08 33.5 10.9 8.5e-08 32.2 10.9 1.8 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 GBG92314.1 - 9.3e-10 38.4 6.7 1.8e-09 37.5 6.7 1.5 1 0 0 1 1 1 1 MYND finger DUF3446 PF11928.8 GBG92314.1 - 0.05 13.9 21.5 0.048 14.0 6.8 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Chorion_2 PF03964.15 GBG92314.1 - 3.6 8.5 8.7 21 6.0 3.0 2.3 2 0 0 2 2 2 0 Chorion family 2 DIL PF01843.19 GBG92315.1 - 1.8e-24 86.0 0.8 3.5e-24 85.1 0.8 1.5 1 0 0 1 1 1 1 DIL domain Glyco_hydro_38N PF01074.22 GBG92316.1 - 1.1e-88 297.4 5.7 1.7e-88 296.8 5.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 GBG92316.1 - 1.4e-17 63.6 1.0 2.6e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 GBG92316.1 - 1.7e-17 64.2 0.0 3.3e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Oleosin PF01277.17 GBG92317.1 - 1.5e-14 53.7 4.6 1.5e-14 53.7 4.6 2.2 2 0 0 2 2 2 1 Oleosin REF PF05755.12 GBG92317.1 - 0.0013 18.6 1.4 0.0023 17.8 1.4 1.4 1 0 0 1 1 1 1 Rubber elongation factor protein (REF) DUF2207 PF09972.9 GBG92317.1 - 0.017 13.9 4.0 0.055 12.2 4.0 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FUSC PF04632.12 GBG92317.1 - 0.049 12.2 5.4 0.072 11.6 5.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family LEA_4 PF02987.16 GBG92317.1 - 1.5 9.0 14.2 0.86 9.7 7.8 2.3 2 1 0 2 2 2 0 Late embryogenesis abundant protein MIP PF00230.20 GBG92319.1 - 9.6e-71 238.1 16.8 9.6e-71 238.1 16.8 2.1 1 1 1 2 2 2 2 Major intrinsic protein Proteasome PF00227.26 GBG92320.1 - 9.7e-62 207.8 0.1 1.2e-61 207.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GBG92320.1 - 3.2e-14 52.3 0.1 6.7e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1011 PF06237.12 GBG92321.1 - 0.03 14.6 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1011) Defensin_int PF17858.1 GBG92322.1 - 0.12 12.4 1.0 17 5.5 0.4 2.3 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide EBP PF05241.12 GBG92323.1 - 2.2e-29 102.2 0.6 2.7e-29 101.9 0.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein MatE PF01554.18 GBG92324.1 - 2.8e-49 166.9 31.6 2.3e-30 105.4 11.6 2.2 2 0 0 2 2 2 2 MatE Spc7 PF08317.11 GBG92325.1 - 0.03 13.2 8.4 0.065 12.1 8.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 GBG92325.1 - 0.041 13.6 8.3 0.22 11.3 0.7 2.9 1 1 1 2 2 2 0 Septum formation initiator Phage_GPO PF05929.11 GBG92325.1 - 0.062 12.9 2.3 0.12 12.0 2.3 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase YscK PF06578.12 GBG92325.1 - 0.075 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Med9 PF07544.13 GBG92325.1 - 0.12 12.5 5.4 0.18 11.9 0.5 3.2 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.11 GBG92325.1 - 0.13 12.7 6.5 0.54 10.7 0.2 3.1 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Barstar PF01337.18 GBG92325.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Barstar (barnase inhibitor) HALZ PF02183.18 GBG92325.1 - 0.21 11.8 15.7 1.8 8.9 0.4 4.8 3 1 1 4 4 4 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 GBG92325.1 - 0.7 10.0 10.6 1.8 8.6 8.3 2.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1640 PF07798.11 GBG92325.1 - 5.1 7.1 10.2 27 4.7 8.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) MatE PF01554.18 GBG92326.1 - 7.1e-56 188.3 28.8 1.8e-33 115.5 8.8 2.2 2 0 0 2 2 2 2 MatE Sporozoite_P67 PF05642.11 GBG92326.1 - 4.1 5.4 4.3 6.2 4.8 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen rve PF00665.26 GBG92327.1 - 9.2e-10 38.7 0.0 2.2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG92327.1 - 7.6e-06 26.2 0.0 0.00018 21.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG92327.1 - 5.4e-05 23.7 0.0 0.00015 22.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 GBG92327.1 - 0.00014 21.8 0.1 0.00033 20.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG92327.1 - 0.00039 21.0 0.0 0.0011 19.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92327.1 - 0.0022 17.8 0.2 0.0092 15.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG92327.1 - 0.033 14.5 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG92327.1 - 0.04 14.2 0.1 0.37 11.1 0.0 2.6 1 1 1 2 2 2 0 Retrotransposon gag protein DDHD PF02862.17 GBG92328.1 - 0.64 10.1 5.1 0.83 9.8 0.5 2.3 2 0 0 2 2 2 0 DDHD domain Nup160 PF11715.8 GBG92329.1 - 3.1e-08 32.8 0.0 4.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Retrotrans_gag PF03732.17 GBG92329.1 - 0.0097 16.2 1.0 0.043 14.1 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG92330.1 - 1.2e-29 103.4 0.1 2e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92330.1 - 5.2e-18 64.9 0.0 1.5e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5311 PF17238.2 GBG92330.1 - 6.1e-12 45.9 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5311) Nup160 PF11715.8 GBG92330.1 - 2.3e-11 43.1 2.2 3.6e-11 42.4 2.2 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 RT_RNaseH PF17917.1 GBG92330.1 - 2.3e-09 37.5 0.0 7.2e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG92330.1 - 6.4e-08 33.1 0.0 1.5e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92330.1 - 4.8e-07 30.3 0.0 1.4e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92330.1 - 1.6e-06 27.9 0.0 3.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92330.1 - 4.3e-06 26.5 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease V-SNARE_C PF12352.8 GBG92330.1 - 0.081 13.2 0.3 0.2 11.9 0.3 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus DUF4916 PF16262.5 GBG92330.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) RVT_1 PF00078.27 GBG92331.1 - 1.3e-29 103.4 0.1 2e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92331.1 - 5.2e-18 64.9 0.0 1.5e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5311 PF17238.2 GBG92331.1 - 6.1e-12 45.9 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5311) Nup160 PF11715.8 GBG92331.1 - 2.2e-11 43.1 2.2 3.6e-11 42.4 2.2 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 RT_RNaseH PF17917.1 GBG92331.1 - 2.3e-09 37.5 0.0 7.2e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG92331.1 - 6.5e-08 33.0 0.0 1.5e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92331.1 - 4.9e-07 30.3 0.0 1.4e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92331.1 - 1.6e-06 27.9 0.0 3.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92331.1 - 4.3e-06 26.5 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease V-SNARE_C PF12352.8 GBG92331.1 - 0.081 13.2 0.3 0.2 11.9 0.3 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus DUF4916 PF16262.5 GBG92331.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) DUF659 PF04937.15 GBG92332.1 - 4.5e-32 111.0 0.0 8.5e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92332.1 - 3.4e-10 39.6 0.2 8e-10 38.4 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Methyltransf_34 PF11312.8 GBG92333.1 - 0.015 14.6 4.6 0.21 10.8 0.2 2.1 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase DUF1676 PF07898.13 GBG92333.1 - 0.29 11.2 15.5 0.13 12.3 4.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) Presenilin PF01080.17 GBG92333.1 - 0.75 8.5 10.4 1.1 7.9 10.4 1.3 1 0 0 1 1 1 0 Presenilin Orf78 PF06024.12 GBG92333.1 - 1.4 9.2 5.1 2.5 8.4 2.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) DUF4604 PF15377.6 GBG92333.1 - 2.2 8.6 29.7 0.52 10.7 26.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) EIIBC-GUT_N PF03612.14 GBG92333.1 - 2.7 7.7 13.9 6.5 6.5 5.8 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus OAD_gamma PF04277.13 GBG92333.1 - 2.9 8.5 8.6 15 6.3 0.7 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Nop14 PF04147.12 GBG92333.1 - 3.5 5.7 23.2 6.5 4.8 23.2 1.3 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 GBG92333.1 - 5.2 7.1 38.4 0.11 12.6 5.8 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3899 PF13038.6 GBG92333.1 - 7.3 7.2 7.5 5.1 7.7 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF2889 PF11136.8 GBG92334.1 - 0.19 12.1 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) DTC PF18102.1 GBG92335.1 - 1.1e-05 25.6 0.0 1.4e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Deltex C-terminal domain SDA1 PF05285.12 GBG92335.1 - 0.019 14.4 22.3 0.019 14.4 22.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG92335.1 - 0.022 13.0 22.6 0.021 13.1 22.6 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 GBG92335.1 - 0.039 13.4 19.2 0.044 13.2 19.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 GBG92335.1 - 0.35 11.3 1.8 0.41 11.1 1.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 GBG92335.1 - 0.58 9.1 3.1 0.55 9.2 3.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mpp10 PF04006.12 GBG92335.1 - 0.93 7.9 22.4 1 7.7 22.4 1.0 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 GBG92335.1 - 1.9 7.2 8.8 1.7 7.3 8.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein IFT57 PF10498.9 GBG92335.1 - 2.4 7.1 12.5 3 6.7 12.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Tim54 PF11711.8 GBG92335.1 - 2.6 6.7 6.1 2.9 6.6 6.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2076 PF09849.9 GBG92335.1 - 3.4 7.6 15.7 3.9 7.5 15.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) BUD22 PF09073.10 GBG92335.1 - 3.8 6.8 24.1 3.8 6.7 24.1 1.1 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 GBG92335.1 - 4.1 7.2 13.5 4.7 7.0 13.5 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 GBG92336.1 - 0.42 8.8 4.6 0.54 8.4 4.6 1.0 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG92337.1 - 7.8e-26 91.0 0.1 1.5e-25 90.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92337.1 - 6.3e-14 51.8 0.1 1.8e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG92337.1 - 0.001 19.1 3.5 0.0028 17.7 3.5 1.8 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG92337.1 - 0.0029 17.4 0.0 0.0074 16.1 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 GBG92337.1 - 0.0048 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG92337.1 - 0.01 16.4 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92337.1 - 0.049 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG92337.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG92337.1 - 0.19 11.5 4.9 0.5 10.2 4.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Cwf_Cwc_15 PF04889.12 GBG92337.1 - 2.2 7.9 17.3 23 4.6 15.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG92337.1 - 8.3 4.5 21.6 22 3.1 21.6 1.6 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG92338.1 - 2.2 6.4 6.2 2.9 6.1 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG92338.1 - 2.6 6.2 6.9 3.2 5.8 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family Chromo PF00385.24 GBG92339.1 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SGL PF08450.12 GBG92340.1 - 0.00027 20.6 0.4 0.0077 15.8 0.0 2.8 2 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region N6_N4_Mtase PF01555.18 GBG92342.1 - 9.6e-05 22.2 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 DNA methylase DUF4736 PF15883.5 GBG92342.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) DUF3381 PF11861.8 GBG92343.1 - 0.1 12.4 9.1 0.17 11.7 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Nop14 PF04147.12 GBG92343.1 - 2.2 6.4 14.5 2.9 6.0 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH_2 PF17919.1 GBG92344.1 - 1.2e-29 102.3 0.0 2.7e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92344.1 - 7.4e-28 96.9 0.0 2.7e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RNA_pol_3_Rpc31 PF11705.8 GBG92344.1 - 0.022 15.0 14.6 0.022 15.0 14.6 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CSRNP_N PF16019.5 GBG92344.1 - 2.3 8.1 14.0 0.18 11.7 4.7 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus 2OG-FeII_Oxy_2 PF13532.6 GBG92344.1 - 4 7.6 5.5 18 5.4 2.6 2.7 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily LAP1C PF05609.12 GBG92344.1 - 4.2 6.4 21.2 5.7 5.9 21.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Pkinase_Tyr PF07714.17 GBG92345.1 - 1.6e-37 129.2 0.0 3.1e-37 128.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG92345.1 - 1.8e-33 116.0 0.0 3.2e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG92345.1 - 0.016 14.0 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GBG92345.1 - 0.023 14.6 0.0 0.086 12.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family CAP_N PF01213.19 GBG92345.1 - 4.2 6.8 4.3 12 5.3 4.3 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Dimer_Tnp_hAT PF05699.14 GBG92346.1 - 0.026 14.3 0.0 0.075 12.8 0.0 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Radical_SAM PF04055.21 GBG92347.1 - 2.5e-23 83.3 0.0 3.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GBG92347.1 - 1e-13 51.8 0.0 1.7e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 GBG92347.1 - 2.7e-06 27.5 0.0 7.1e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain MPM1 PF17234.2 GBG92347.1 - 0.35 11.1 1.3 0.6 10.3 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Exo70 PF03081.15 GBG92348.1 - 3.1e-99 332.6 3.2 5.4e-99 331.8 0.2 2.2 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Mis12 PF05859.12 GBG92348.1 - 0.051 13.6 0.0 0.19 11.8 0.0 2.1 1 1 0 1 1 1 0 Mis12 protein DUF2935 PF11155.8 GBG92348.1 - 0.17 12.2 2.7 0.38 11.1 0.4 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) Sec34 PF04136.15 GBG92348.1 - 0.64 9.9 3.9 1.9 8.4 2.0 2.7 2 1 0 2 2 2 0 Sec34-like family Ribosomal_L5_C PF00673.21 GBG92349.1 - 6e-21 74.4 0.0 9.8e-21 73.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GBG92349.1 - 5.1e-20 71.6 0.0 7.9e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Nop14 PF04147.12 GBG92350.1 - 1.9 6.6 29.1 2.7 6.1 29.1 1.1 1 0 0 1 1 1 0 Nop14-like family Plasmodium_Vir PF05795.11 GBG92350.1 - 2 7.7 6.5 2.6 7.4 6.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Vfa1 PF08432.10 GBG92350.1 - 4.3 7.6 14.4 6.8 7.0 14.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.10 GBG92350.1 - 5.6 6.2 33.4 7.8 5.7 33.4 1.1 1 0 0 1 1 1 0 BUD22 DUF4091 PF13320.6 GBG92352.1 - 6.6e-17 61.4 0.2 2.2e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4091) Kinesin PF00225.23 GBG92353.1 - 1.3e-103 346.5 0.0 1.9e-103 345.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GBG92353.1 - 6.1e-19 68.4 0.0 2.4e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Rootletin PF15035.6 GBG92353.1 - 0.033 14.2 1.6 0.062 13.3 1.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ABC_membrane PF00664.23 GBG92354.1 - 3e-36 125.5 10.5 3.9e-36 125.1 10.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GBG92354.1 - 1.6e-33 116.1 0.0 3.2e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GBG92354.1 - 8.2e-10 38.5 0.1 5.3e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GBG92354.1 - 7.3e-05 23.2 0.1 0.00016 22.1 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GBG92354.1 - 0.00026 20.7 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 GBG92354.1 - 0.0022 17.7 0.1 0.009 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 GBG92354.1 - 0.0031 17.3 0.0 0.0053 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 GBG92354.1 - 0.0038 17.1 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GBG92354.1 - 0.005 17.1 0.2 0.045 14.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GBG92354.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 GBG92354.1 - 0.012 15.7 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 GBG92354.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 GBG92354.1 - 0.015 14.2 0.0 0.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 GBG92354.1 - 0.017 15.6 0.1 0.21 12.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 GBG92354.1 - 0.019 15.5 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 GBG92354.1 - 0.019 14.7 0.0 0.057 13.2 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF3088 PF11287.8 GBG92354.1 - 0.034 13.9 0.0 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3088) Zeta_toxin PF06414.12 GBG92354.1 - 0.061 12.6 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin G-alpha PF00503.20 GBG92354.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Rad17 PF03215.15 GBG92354.1 - 0.22 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain PRIMA1 PF16101.5 GBG92354.1 - 4.8 7.2 10.3 13 5.8 10.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 P_proprotein PF01483.20 GBG92355.1 - 1.1e-16 60.6 0.0 8.1e-08 32.2 0.0 2.7 2 0 0 2 2 2 2 Proprotein convertase P-domain GLTT PF01744.20 GBG92355.1 - 9.8e-07 28.4 0.7 0.0047 16.6 0.2 2.7 1 1 1 2 2 2 2 GLTT repeat (6 copies) Myb_DNA-bind_4 PF13837.6 GBG92355.1 - 1.9e-05 24.9 2.2 1.9e-05 24.9 2.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG92355.1 - 0.0074 16.3 1.2 0.02 14.9 1.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MDM1 PF15501.6 GBG92355.1 - 1.1 8.4 13.7 2.2 7.3 13.7 1.4 1 0 0 1 1 1 0 Nuclear protein MDM1 Hid1 PF12722.7 GBG92355.1 - 1.8 6.6 2.9 3 5.8 2.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein p450 PF00067.22 GBG92357.1 - 8.9e-81 272.0 0.0 1.9e-79 267.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 CAP_N PF01213.19 GBG92357.1 - 8.1 5.8 8.7 1.9 7.9 5.1 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pribosyltran_N PF13793.6 GBG92359.1 - 3.6e-08 33.4 0.0 1.4e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 GBG92359.1 - 7.2e-07 28.9 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 GBG92359.1 - 0.00032 20.8 0.0 0.00056 20.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Myb_DNA-bind_4 PF13837.6 GBG92360.1 - 1.9e-06 28.2 1.2 5.2e-06 26.7 0.5 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG92360.1 - 0.0013 18.7 2.5 0.0022 18.0 0.5 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain HemY_N PF07219.13 GBG92360.1 - 0.059 13.6 0.7 4.8 7.4 0.0 2.7 3 0 0 3 3 3 0 HemY protein N-terminus MADF_DNA_bdg PF10545.9 GBG92360.1 - 0.15 12.4 0.2 0.15 12.4 0.2 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GRP PF07172.11 GBG92360.1 - 1.5 9.5 13.9 1.3e+02 3.4 14.1 2.7 2 0 0 2 2 2 0 Glycine rich protein family DDE_Tnp_4 PF13359.6 GBG92362.1 - 1.6e-31 109.1 0.0 7.4e-31 107.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92362.1 - 1.7e-12 47.4 0.0 2.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92362.1 - 0.017 14.7 1.0 4.8 6.8 0.0 3.4 3 0 0 3 3 3 0 Transposase DDE domain DUF659 PF04937.15 GBG92364.1 - 5.3e-39 133.5 0.0 9.8e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92364.1 - 2e-05 24.3 0.0 4.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 GBG92364.1 - 0.015 15.3 0.6 0.032 14.3 0.6 1.6 1 0 0 1 1 1 0 BED zinc finger Utp14 PF04615.13 GBG92364.1 - 0.059 12.0 18.3 0.09 11.3 18.3 1.2 1 0 0 1 1 1 0 Utp14 protein AT_hook PF02178.19 GBG92364.1 - 0.83 9.7 14.9 1.1 9.4 2.1 3.2 2 0 0 2 2 2 0 AT hook motif Menin PF05053.13 GBG92364.1 - 6.6 5.0 8.8 11 4.2 8.8 1.3 1 0 0 1 1 1 0 Menin Glyco_hydro_14 PF01373.17 GBG92366.1 - 7.4e-139 463.1 0.0 9e-139 462.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Integrase_H2C2 PF17921.1 GBG92368.1 - 9.4e-13 48.1 0.2 2.2e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92368.1 - 9.7e-05 22.5 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG92368.1 - 0.00026 21.1 0.0 0.00058 20.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Angiomotin_C PF12240.8 GBG92368.1 - 0.0014 18.2 2.2 0.0018 17.9 0.2 2.1 2 0 0 2 2 2 1 Angiomotin C terminal zf-CCHC PF00098.23 GBG92368.1 - 0.08 13.0 0.7 0.29 11.3 0.7 2.0 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG92369.1 - 2.2e-14 53.6 0.0 3.9e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92369.1 - 0.18 11.6 0.1 0.66 9.8 0.0 2.0 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region CDC45 PF02724.14 GBG92369.1 - 2.1 6.6 12.4 3.9 5.6 12.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Integrase_H2C2 PF17921.1 GBG92370.1 - 2.8e-20 72.2 0.4 6.2e-20 71.1 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG92370.1 - 1e-15 57.9 0.1 2.5e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92370.1 - 1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG92370.1 - 3e-08 33.5 0.0 6.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92370.1 - 4.5e-07 30.4 0.0 9.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92370.1 - 0.0004 20.9 0.0 0.00082 19.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease IL28A PF15177.6 GBG92370.1 - 0.0022 17.9 5.6 0.0043 16.9 5.6 1.4 1 0 0 1 1 1 1 Interleukin-28A DUF446 PF04287.12 GBG92372.1 - 0.11 12.6 0.1 1 9.5 0.0 2.3 2 1 0 2 2 2 0 tRNA pseudouridine synthase C RVT_1 PF00078.27 GBG92374.1 - 6.4e-23 81.4 0.0 1.9e-22 79.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92374.1 - 1.5e-21 76.3 0.0 3.3e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92374.1 - 1.3e-15 57.2 0.3 3.6e-15 55.8 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG92374.1 - 1.9e-14 53.8 0.0 4.9e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG92374.1 - 7e-08 32.3 0.0 6.9e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92374.1 - 2.7e-07 31.1 0.0 8e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG92374.1 - 1e-06 28.9 0.0 3.7e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG92374.1 - 2.9e-05 24.5 0.0 9.5e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92374.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.12 GBG92374.1 - 0.28 11.8 1.0 1.5 9.5 0.2 2.7 1 1 1 2 2 2 0 SlyX RVT_1 PF00078.27 GBG92376.1 - 6.8e-30 104.2 0.1 1.1e-29 103.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG92376.1 - 6.7e-15 54.9 0.1 6.7e-15 54.9 0.1 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG92376.1 - 6.9e-12 45.6 0.0 1.9e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG92376.1 - 3.9e-06 27.0 0.0 1.4e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger SAPS PF04499.15 GBG92377.1 - 0.014 14.2 7.6 0.017 13.9 7.6 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4569 PF15133.6 GBG92377.1 - 9.8 5.8 11.9 15 5.2 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) LRR_6 PF13516.6 GBG92378.1 - 6.1e-08 32.1 1.4 0.0005 19.9 0.1 5.4 5 0 0 5 5 5 1 Leucine Rich repeat F-box_5 PF18511.1 GBG92378.1 - 6.7e-06 25.6 0.2 1.5e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 GBG92378.1 - 5.3e-05 23.0 0.3 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GBG92378.1 - 0.00034 20.9 0.2 4.8 7.7 0.0 5.2 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GBG92378.1 - 0.0029 17.4 0.1 0.0029 17.4 0.1 2.2 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 GBG92378.1 - 0.012 16.0 0.2 83 4.4 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat DUF1223 PF06764.11 GBG92379.1 - 0.3 11.1 9.1 0.12 12.3 6.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1223) DUF3138 PF11336.8 GBG92379.1 - 0.84 8.2 1.9 1.6 7.3 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RVT_1 PF00078.27 GBG92380.1 - 5.3e-17 62.1 0.0 8.4e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92380.1 - 4.3e-12 45.9 0.0 8.9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG92380.1 - 2.5e-11 43.5 0.0 1.1e-10 41.5 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92380.1 - 9.2e-10 39.0 0.0 1.8e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92380.1 - 9.1e-07 29.4 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG92380.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 GBG92380.1 - 0.035 13.9 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG92380.1 - 0.11 12.9 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease SlyX PF04102.12 GBG92380.1 - 1.2 9.8 7.5 0.11 13.1 0.5 2.7 2 0 0 2 2 2 0 SlyX RT_RNaseH PF17917.1 GBG92381.1 - 7.1e-24 84.1 0.0 1.4e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92381.1 - 5e-23 81.0 0.0 8.8e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92381.1 - 4.3e-18 65.2 0.1 1e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG92381.1 - 4.2e-10 39.5 0.4 1.3e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG92381.1 - 1.3e-08 35.1 0.0 4e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Macoilin PF09726.9 GBG92384.1 - 0.084 11.4 3.8 0.099 11.2 3.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF2312 PF10073.9 GBG92384.1 - 0.18 11.4 2.6 0.35 10.5 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) SVIP PF15811.5 GBG92384.1 - 0.29 11.6 6.0 9.5 6.8 0.1 3.2 2 1 0 2 2 2 0 Small VCP/p97-interacting protein DivIC PF04977.15 GBG92384.1 - 0.46 10.3 4.8 1.5 8.6 0.3 2.8 3 0 0 3 3 3 0 Septum formation initiator KELK PF15796.5 GBG92384.1 - 4.7 7.7 10.8 7 7.2 0.3 3.2 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PQQ_3 PF13570.6 GBG92385.1 - 0.065 13.7 3.8 2.1 9.0 0.2 4.1 4 0 0 4 4 4 0 PQQ-like domain BAT PF15915.5 GBG92385.1 - 0.1 12.5 0.0 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 GAF and HTH_10 associated domain SGL PF08450.12 GBG92385.1 - 0.19 11.3 0.0 8.4 5.9 0.0 2.6 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Pkinase_Tyr PF07714.17 GBG92390.1 - 4.6e-41 140.8 0.0 1.2e-40 139.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG92390.1 - 3.3e-39 134.9 0.0 4.4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG92390.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GBG92390.1 - 0.038 13.9 0.0 7.2 6.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RVT_1 PF00078.27 GBG92391.1 - 3.6e-26 92.0 0.0 6.3e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92391.1 - 5.5e-22 78.0 0.1 1.2e-21 77.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92391.1 - 7.8e-13 48.3 0.2 2.6e-12 46.7 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG92391.1 - 8.3e-13 48.2 0.0 2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92391.1 - 1.5e-12 47.7 0.1 6.3e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG92391.1 - 0.0036 17.5 0.0 0.01 16.0 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger ATP_bind_3 PF01171.20 GBG92392.1 - 1.3e-16 60.9 0.0 1.9e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 GBG92392.1 - 3.4e-15 55.3 2.9 3.4e-15 55.3 2.9 3.0 3 0 0 3 3 3 1 Zinc-ribbon PAPS_reduct PF01507.19 GBG92392.1 - 0.001 19.2 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 GBG92392.1 - 0.0022 17.6 0.1 0.034 13.7 0.0 2.2 1 1 1 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 GBG92392.1 - 0.0085 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase CTU2 PF10288.9 GBG92392.1 - 0.021 15.1 2.0 0.14 12.4 0.6 2.5 2 2 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 RecR PF02132.15 GBG92392.1 - 4.6 6.9 9.1 0.22 11.1 1.3 2.6 3 0 0 3 3 3 0 RecR protein RRM_1 PF00076.22 GBG92393.1 - 2e-17 62.7 0.1 3.4e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Inhibitor_I71 PF12628.7 GBG92393.1 - 0.17 11.7 0.1 0.49 10.2 0.1 1.7 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor UvrD_C PF13361.6 GBG92397.1 - 9.5e-33 114.0 0.0 9.2e-32 110.8 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 GBG92397.1 - 4.7e-12 45.5 0.5 3.7e-11 42.7 0.5 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 GBG92397.1 - 0.0013 18.4 0.1 0.0042 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GBG92397.1 - 0.013 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF3072 PF11272.8 GBG92398.1 - 0.046 13.6 0.2 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3072) VBS PF08913.10 GBG92398.1 - 0.06 13.8 0.1 0.11 13.0 0.1 1.4 1 1 0 1 1 1 0 Vinculin Binding Site DNA_topoisoIV PF00521.20 GBG92399.1 - 8.3e-133 443.4 0.0 1.4e-132 442.7 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GBG92399.1 - 2.4e-50 170.1 1.0 5.7e-50 168.9 1.0 1.7 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GBG92399.1 - 9.9e-24 83.7 0.4 2.1e-23 82.7 0.4 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 GBG92399.1 - 2.3e-11 44.2 0.0 7.7e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GBG92399.1 - 7.9e-08 32.5 0.0 2.4e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Toprim domain tRNA-synt_1g PF09334.11 GBG92400.1 - 4.7e-133 443.7 0.0 8.1e-93 311.3 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA_bind PF01588.20 GBG92400.1 - 3.9e-31 107.0 0.1 7.4e-31 106.1 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 GBG92400.1 - 3e-06 25.8 0.0 0.0023 16.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GBG92400.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA C1_1 PF00130.22 GBG92400.1 - 1.1 9.2 5.2 2.7 7.9 0.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1272 PF06906.11 GBG92400.1 - 1.1 9.4 5.7 0.23 11.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 GBG92400.1 - 2.5 8.2 13.3 0.52 10.4 6.2 2.8 2 1 1 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 GBG92400.1 - 3.7 7.6 6.7 14 5.8 6.5 2.0 1 1 0 1 1 1 0 zinc-ribbons HypA PF01155.19 GBG92400.1 - 6.7 6.8 6.3 4e+02 1.1 6.3 2.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HC5 PF06221.13 GBG92400.1 - 8.8 6.4 6.7 4.7 7.3 0.6 2.5 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type tRNA-synt_1_2 PF13603.6 GBG92402.1 - 0.077 12.5 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 RT_RNaseH_2 PF17919.1 GBG92403.1 - 8e-35 118.9 0.0 2e-34 117.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92403.1 - 1e-30 106.1 0.0 2.6e-30 104.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92403.1 - 4.7e-16 58.6 0.1 1e-15 57.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92403.1 - 3.8e-15 56.1 0.0 9.8e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain LMBR1 PF04791.16 GBG92403.1 - 0.029 13.3 4.1 0.055 12.4 4.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein CD99L2 PF12301.8 GBG92404.1 - 0.45 10.8 5.5 0.9 9.8 0.8 2.7 2 0 0 2 2 2 0 CD99 antigen like protein 2 RT_RNaseH PF17917.1 GBG92405.1 - 3.1e-30 104.5 0.1 8.7e-30 103.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92405.1 - 1.3e-29 102.2 0.0 3.2e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92405.1 - 2.9e-11 43.3 0.1 2.5e-07 30.5 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GPO PF05929.11 GBG92405.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Nop14 PF04147.12 GBG92405.1 - 1.5 6.9 23.1 2.4 6.3 23.1 1.2 1 0 0 1 1 1 0 Nop14-like family ADP_ribosyl_GH PF03747.14 GBG92405.1 - 1.6 8.4 3.9 36 3.9 3.3 3.2 3 1 0 3 3 3 0 ADP-ribosylglycohydrolase V_ATPase_I PF01496.19 GBG92405.1 - 4.5 5.1 5.6 60 1.3 6.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pet100 PF09803.9 GBG92405.1 - 8.9 6.9 8.0 8 7.1 0.0 3.3 1 1 1 2 2 2 0 Pet100 RT_RNaseH_2 PF17919.1 GBG92406.1 - 1.3e-22 79.7 0.0 2.3e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92406.1 - 4.7e-20 71.8 0.0 1.3e-19 70.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92406.1 - 2.7e-14 53.4 0.0 6.1e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG92406.1 - 3.6e-11 43.0 0.1 9.8e-11 41.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG92406.1 - 0.00028 21.4 0.0 0.00065 20.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG92406.1 - 0.0013 19.0 0.1 0.0033 17.7 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92406.1 - 0.0039 17.8 0.0 0.0093 16.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG92406.1 - 0.006 16.1 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG92406.1 - 0.15 12.2 0.8 0.55 10.4 0.8 2.1 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92406.1 - 0.34 10.8 4.6 0.078 12.8 0.7 2.1 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG92407.1 - 0.00086 19.8 0.0 0.0022 18.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92407.1 - 0.0072 16.9 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92407.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG92407.1 - 0.028 14.7 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease alpha-hel2 PF14456.6 GBG92407.1 - 0.14 11.4 0.5 0.27 10.5 0.5 1.4 1 0 0 1 1 1 0 Alpha-helical domain 2 JmjC PF02373.22 GBG92408.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase XRN_N PF03159.18 GBG92408.1 - 0.063 12.7 2.8 0.14 11.5 2.8 1.5 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus FBPase_glpX PF03320.13 GBG92408.1 - 0.12 11.2 1.0 0.22 10.3 1.0 1.3 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded RVT_1 PF00078.27 GBG92410.1 - 1.5e-28 99.8 0.1 2.5e-28 99.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG92410.1 - 2.1e-11 43.5 0.0 4.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG92411.1 - 9.8e-33 112.2 0.2 3e-32 110.6 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92411.1 - 1.3e-28 99.3 0.2 2.7e-28 98.3 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG92411.1 - 7.3e-07 29.0 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG92411.1 - 1.5e-06 28.7 0.0 4.2e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92411.1 - 2.6e-06 28.0 0.0 6.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92411.1 - 2e-05 24.4 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF4596 PF15363.6 GBG92411.1 - 0.4 11.0 2.6 1.4 9.2 2.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Herpes_heli_pri PF05774.11 GBG92412.1 - 0.049 13.9 0.6 0.23 11.7 0.0 2.4 3 0 0 3 3 3 0 Herpesvirus helicase-primase complex component XRN_M PF17846.1 GBG92412.1 - 0.086 11.8 0.1 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 Xrn1 helical domain RVT_1 PF00078.27 GBG92413.1 - 2.8e-36 125.1 0.1 5e-36 124.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_lysozyme PF00959.19 GBG92413.1 - 0.025 15.0 0.1 0.33 11.4 0.0 2.6 2 0 0 2 2 2 0 Phage lysozyme gpUL132 PF11359.8 GBG92413.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 RVT_1 PF00078.27 GBG92414.1 - 4.4e-13 49.2 0.7 1e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG92414.1 - 2.4e-09 37.1 0.0 7.8e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92414.1 - 2.5e-07 31.2 0.0 7e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92414.1 - 4.7e-06 27.1 0.0 1.2e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG92414.1 - 0.0012 19.1 0.6 0.0034 17.6 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG92414.1 - 0.0036 17.1 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG92414.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG92415.1 - 5.1e-33 113.1 0.1 9.9e-33 112.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92415.1 - 6.1e-29 100.4 0.1 1.5e-28 99.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92415.1 - 1.2e-18 66.9 0.1 2.3e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92415.1 - 7.2e-16 58.5 0.1 5.6e-15 55.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG92415.1 - 0.02 15.1 0.0 0.064 13.5 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger LPD11 PF18824.1 GBG92416.1 - 0.021 14.9 0.1 0.078 13.1 0.1 1.9 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 MatE PF01554.18 GBG92417.1 - 3.6e-58 195.8 27.3 6.3e-31 107.2 6.7 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GBG92417.1 - 2.2e-05 24.6 15.1 2.2e-05 24.6 15.1 3.7 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Lebercilin PF15619.6 GBG92418.1 - 0.01 15.5 17.9 0.019 14.6 17.9 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Macoilin PF09726.9 GBG92418.1 - 0.032 12.8 17.5 0.037 12.6 17.5 1.0 1 0 0 1 1 1 0 Macoilin family DUF1840 PF08895.11 GBG92418.1 - 0.076 13.4 11.2 0.048 14.0 8.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) PIN_12 PF16289.5 GBG92418.1 - 0.097 13.2 7.6 0.16 12.4 7.6 1.4 1 0 0 1 1 1 0 PIN domain DUF4471 PF14740.6 GBG92418.1 - 0.13 11.5 5.4 0.21 10.7 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF2407_C PF13373.6 GBG92418.1 - 0.25 11.5 2.5 0.47 10.6 2.5 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain DASH_Dad2 PF08654.10 GBG92418.1 - 0.27 11.7 0.2 0.27 11.7 0.2 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad2 Baculo_PEP_C PF04513.12 GBG92418.1 - 1.6 8.7 8.2 2.4e+02 1.7 8.1 2.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Plasmid_RAQPRD PF09686.10 GBG92418.1 - 3.3 8.0 10.8 0.16 12.2 0.4 3.2 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) UPF0242 PF06785.11 GBG92418.1 - 3.4 7.7 15.2 5.5 7.0 15.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ArgoN PF16486.5 GBG92418.1 - 3.7 8.2 6.1 3.4 8.3 4.0 2.2 1 1 1 2 2 2 0 N-terminal domain of argonaute CCDC53 PF10152.9 GBG92418.1 - 4.5 7.7 12.6 1.3 9.4 1.3 2.2 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex FAM76 PF16046.5 GBG92418.1 - 5.4 6.3 12.8 7.9 5.7 12.8 1.2 1 0 0 1 1 1 0 FAM76 protein HAUS6_N PF14661.6 GBG92418.1 - 7.4 6.1 13.8 6.4 6.3 12.6 1.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus RVT_1 PF00078.27 GBG92422.1 - 7.2e-29 100.9 0.0 1.3e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LPD25 PF18840.1 GBG92423.1 - 1.2 9.7 7.4 3.6 8.2 7.4 1.9 1 1 0 1 1 1 0 Large polyvalent protein associated domain 25 Chromo PF00385.24 GBG92424.1 - 3.2e-05 23.7 0.2 7.5e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG92424.1 - 0.0011 18.7 0.4 0.0027 17.4 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG92424.1 - 0.02 15.1 1.6 0.2 12.0 0.0 3.1 3 0 0 3 3 3 0 Retrotransposon gag protein Lipin_mid PF16876.5 GBG92424.1 - 0.089 13.0 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Ndc1_Nup PF09531.10 GBG92424.1 - 0.52 8.9 3.0 0.16 10.6 0.2 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup RVT_1 PF00078.27 GBG92425.1 - 1.3e-38 132.7 0.0 1.9e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_1 PF00515.28 GBG92426.1 - 4.4e-08 32.6 0.4 1.6e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GBG92426.1 - 4.7e-05 23.0 0.0 0.18 11.5 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 GBG92426.1 - 4.8e-05 23.2 0.3 0.00092 19.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GBG92426.1 - 8.3e-05 23.1 0.1 0.00064 20.3 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GBG92426.1 - 0.0017 18.4 0.5 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 GBG92426.1 - 0.0024 17.1 0.0 0.0027 17.0 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 GBG92426.1 - 0.013 15.5 0.1 0.054 13.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GBG92426.1 - 0.019 15.3 0.1 0.047 14.0 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GBG92426.1 - 0.047 13.8 0.3 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TAF4 PF05236.14 GBG92427.1 - 0.0025 17.6 2.5 0.0025 17.6 2.5 6.6 2 2 3 6 6 6 1 Transcription initiation factor TFIID component TAF4 family RVT_1 PF00078.27 GBG92428.1 - 1.8e-24 86.5 0.0 2.7e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5321 PF17254.2 GBG92428.1 - 0.0094 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5321) RVT_1 PF00078.27 GBG92429.1 - 2.4e-26 92.6 0.1 9.7e-26 90.6 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92429.1 - 6.2e-24 83.9 0.0 2e-23 82.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92429.1 - 5.1e-22 78.1 0.0 2.1e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92429.1 - 4.1e-16 58.8 0.0 1e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG92429.1 - 0.037 14.3 0.1 0.95 9.8 0.0 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein DUF3006 PF11213.8 GBG92430.1 - 1.8 8.9 4.8 2 8.7 2.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) ERM PF00769.19 GBG92430.1 - 2 8.1 22.6 15 5.3 22.6 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ZapB PF06005.12 GBG92430.1 - 4.6 7.7 12.7 11 6.6 0.1 3.9 3 1 1 4 4 4 0 Cell division protein ZapB RVT_1 PF00078.27 GBG92431.1 - 5e-26 91.6 0.1 7e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG92431.1 - 1.9e-05 24.4 0.0 0.0002 21.1 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92431.1 - 2.5e-05 24.8 0.0 0.00013 22.5 0.0 2.0 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92431.1 - 4e-05 24.1 0.0 0.00018 22.0 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92431.1 - 0.0017 18.2 0.1 0.0076 16.0 0.1 2.0 1 1 0 1 1 1 1 Aspartyl protease Copper-fist PF00649.18 GBG92433.1 - 0.0088 15.5 1.3 0.013 15.0 1.3 1.2 1 0 0 1 1 1 1 Copper fist DNA binding domain COBRA PF04833.15 GBG92434.1 - 5.9e-20 71.8 2.9 5.9e-20 71.8 2.9 2.5 2 1 0 2 2 2 1 COBRA-like protein CBM_2 PF00553.19 GBG92434.1 - 0.022 15.0 4.3 0.8 10.0 0.0 3.2 3 0 0 3 3 3 0 Cellulose binding domain REPA_OB_2 PF16900.5 GBG92435.1 - 5.6e-16 58.3 0.0 1.1e-15 57.3 0.0 1.5 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 GBG92435.1 - 4.4e-06 26.6 0.4 1.9e-05 24.6 0.1 2.2 2 1 1 3 3 3 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 GBG92435.1 - 0.055 13.2 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 zf-CCHC PF00098.23 GBG92436.1 - 1.1e-16 60.1 14.3 3.5e-09 36.3 2.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92436.1 - 7.3e-07 28.9 11.7 0.00019 21.1 1.3 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 GBG92436.1 - 1.2e-05 24.9 13.3 0.012 15.3 4.3 2.4 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 GBG92436.1 - 4e-05 23.5 8.6 0.0077 16.2 1.1 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-GRF PF06839.12 GBG92436.1 - 0.014 15.4 0.9 0.035 14.2 0.9 1.7 1 0 0 1 1 1 0 GRF zinc finger eIF3g PF12353.8 GBG92436.1 - 0.026 14.9 6.0 1.2 9.5 0.3 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.6 GBG92436.1 - 0.04 13.7 5.0 0.79 9.5 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Rubredoxin PF00301.20 GBG92437.1 - 9.7e-16 57.5 3.3 1.9e-15 56.6 3.3 1.5 1 0 0 1 1 1 1 Rubredoxin TF_Zn_Ribbon PF08271.12 GBG92437.1 - 0.019 14.5 1.5 0.69 9.5 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Rubredoxin_2 PF18073.1 GBG92437.1 - 0.042 13.6 4.2 0.07 12.9 0.2 2.6 2 0 0 2 2 2 0 Rubredoxin metal binding domain RNA_POL_M_15KD PF02150.16 GBG92437.1 - 0.06 13.2 0.7 0.06 13.2 0.7 1.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Vps36-NZF-N PF16988.5 GBG92437.1 - 8.2 5.9 7.9 1.8 8.1 0.1 2.6 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-CCHC PF00098.23 GBG92438.1 - 7.5e-05 22.6 3.5 0.00019 21.4 3.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92438.1 - 0.00011 22.0 3.7 0.00024 20.8 3.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GBG92438.1 - 0.034 14.1 2.8 0.11 12.5 2.8 1.8 1 0 0 1 1 1 0 Zinc knuckle Tox-ODYAM1 PF15642.6 GBG92438.1 - 0.19 10.6 7.0 0.3 10.0 7.0 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Rubrerythrin PF02915.17 GBG92439.1 - 7.1e-13 49.1 0.1 1.5e-12 48.1 0.0 1.5 2 0 0 2 2 2 1 Rubrerythrin DEAD PF00270.29 GBG92442.1 - 5.9e-44 149.9 0.1 1.1e-43 149.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG92442.1 - 1.9e-21 76.5 0.0 9e-21 74.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GBG92442.1 - 1.1e-19 70.3 0.0 3.4e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GBG92442.1 - 0.0012 18.8 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dynein_light PF01221.18 GBG92443.1 - 9.5e-33 112.4 0.3 1.1e-32 112.2 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RP853 PF17542.2 GBG92443.1 - 0.048 12.8 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 Ectatomin PF06457.11 GBG92443.1 - 0.1 12.5 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Ectatomin KNOX2 PF03791.13 GBG92444.1 - 0.056 12.9 0.3 0.1 12.1 0.3 1.4 1 0 0 1 1 1 0 KNOX2 domain Secretin_N_2 PF07655.13 GBG92444.1 - 0.88 10.2 9.3 1.8 9.2 9.3 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain UPF0242 PF06785.11 GBG92446.1 - 0.058 13.5 0.4 0.058 13.5 0.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Pectinesterase PF01095.19 GBG92447.1 - 1.5e-79 266.8 0.2 2.1e-79 266.3 0.2 1.1 1 0 0 1 1 1 1 Pectinesterase IHABP4_N PF16174.5 GBG92448.1 - 0.4 11.3 4.7 1.3 9.6 4.7 1.9 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal NAC PF01849.18 GBG92449.1 - 7.3e-26 89.9 0.6 1.6e-25 88.8 0.6 1.6 1 0 0 1 1 1 1 NAC domain DUF3110 PF11360.8 GBG92449.1 - 0.49 10.6 3.7 0.79 10.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) DUF4763 PF15960.5 GBG92449.1 - 0.72 9.1 4.1 4.6 6.5 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF2203 PF09969.9 GBG92449.1 - 4.4 8.0 6.1 0.39 11.4 0.3 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) zf-CCHC PF00098.23 GBG92450.1 - 0.0011 18.9 2.3 0.0011 18.9 2.3 1.8 2 0 0 2 2 2 1 Zinc knuckle AAA_23 PF13476.6 GBG92450.1 - 0.011 16.2 9.8 0.011 16.2 9.8 2.1 2 1 0 2 2 2 0 AAA domain DUF4192 PF13830.6 GBG92450.1 - 0.15 12.1 4.8 0.38 10.8 4.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CHD5 PF04420.14 GBG92450.1 - 1.1 9.2 9.6 2 8.2 9.6 1.4 1 0 0 1 1 1 0 CHD5-like protein DUF5352 PF17303.2 GBG92450.1 - 5.6 6.8 9.2 0.53 10.1 3.6 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5352) zf-CCHC PF00098.23 GBG92451.1 - 0.00047 20.1 1.1 0.00047 20.1 1.1 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92451.1 - 0.13 12.1 2.0 0.26 11.2 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Nop14 PF04147.12 GBG92451.1 - 1.3 7.2 7.4 1.7 6.7 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG92451.1 - 1.7 8.0 8.4 2.6 7.4 8.4 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG92451.1 - 1.7 6.8 5.7 2.4 6.4 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG92451.1 - 2.8 8.0 12.0 1.2 9.2 9.0 1.7 2 0 0 2 2 2 0 YL1 nuclear protein BUD22 PF09073.10 GBG92452.1 - 0.39 10.0 15.8 0.52 9.6 15.8 1.1 1 0 0 1 1 1 0 BUD22 MSA-2c PF12238.8 GBG92452.1 - 0.63 10.0 8.0 0.95 9.4 8.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Nop14 PF04147.12 GBG92452.1 - 2.5 6.2 14.2 3.1 5.9 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG92452.1 - 2.9 7.3 13.8 3.6 6.9 13.8 1.1 1 0 0 1 1 1 0 SDA1 DUF659 PF04937.15 GBG92453.1 - 2.4e-05 24.2 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Co_AT_N PF12557.8 GBG92455.1 - 0.028 14.3 4.7 0.075 13.0 4.7 1.8 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal HSP70 PF00012.20 GBG92457.1 - 1.1e-90 304.6 2.0 1.2e-82 278.0 0.1 2.1 2 0 0 2 2 2 2 Hsp70 protein zf-CCHC PF00098.23 GBG92457.1 - 2.8e-06 27.1 8.5 0.00025 21.0 1.9 2.6 2 0 0 2 2 2 2 Zinc knuckle MreB_Mbl PF06723.13 GBG92457.1 - 0.00026 19.9 1.5 0.00028 19.8 0.1 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GBG92457.1 - 0.00094 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain CbiJ PF02571.14 GBG92457.1 - 0.048 13.1 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Rdx PF10262.9 GBG92459.1 - 4.6e-05 23.5 0.0 5.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Rdx family AAT PF03417.16 GBG92460.1 - 4.7e-26 91.9 0.0 1.4e-25 90.4 0.0 1.6 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Actin PF00022.19 GBG92461.1 - 1.1e-81 274.6 0.0 6.5e-81 272.0 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GBG92461.1 - 0.015 14.1 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein HisKA PF00512.25 GBG92463.1 - 6.2e-06 26.2 0.0 1.8e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 GBG92463.1 - 0.014 15.9 0.1 0.09 13.3 0.0 2.3 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GBG92464.1 - 5.4e-06 26.4 0.0 1.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 GBG92464.1 - 0.013 16.0 0.2 0.071 13.6 0.0 2.3 2 1 1 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zip PF02535.22 GBG92465.1 - 0.31 10.2 0.9 0.39 9.9 0.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RVT_1 PF00078.27 GBG92467.1 - 4.8e-20 72.0 0.0 9.4e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92467.1 - 1.2e-10 41.3 0.0 3.3e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92467.1 - 0.0011 19.3 0.1 0.0048 17.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG92467.1 - 3.1 8.1 5.6 0.56 10.5 0.1 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG92468.1 - 4.5e-31 108.1 0.1 8.8e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92468.1 - 2.1e-30 104.7 0.0 5.1e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92468.1 - 2.9e-26 91.8 0.1 8.4e-26 90.3 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92468.1 - 1e-14 54.4 0.1 6.7e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG92468.1 - 1.1e-10 41.7 0.0 2.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG92468.1 - 1.9e-06 27.7 0.0 4.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92468.1 - 7.4e-06 26.5 0.0 0.0001 22.9 0.0 2.9 3 0 0 3 3 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92468.1 - 0.00067 20.2 0.0 0.0047 17.5 0.0 2.6 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease cNMP_binding PF00027.29 GBG92468.1 - 0.0011 19.0 0.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Asp_protease PF09668.10 GBG92468.1 - 0.0047 16.7 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG92468.1 - 0.0071 16.5 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger Rhamno_transf PF11316.8 GBG92468.1 - 0.08 12.3 0.0 0.25 10.7 0.0 1.9 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF2385 PF09539.10 GBG92468.1 - 0.14 12.7 0.3 0.98 10.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) RVT_1 PF00078.27 GBG92470.1 - 5.8e-27 94.6 0.0 1.2e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92470.1 - 1.2e-20 73.4 0.1 4.2e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92470.1 - 1.9e-20 73.1 0.0 4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92470.1 - 1.8e-10 41.0 0.0 6.9e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 GBG92470.1 - 5.7e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92470.1 - 3.6e-08 33.9 0.0 8.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92470.1 - 6.9e-06 26.5 0.0 2.1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92470.1 - 0.0047 16.7 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG92470.1 - 0.082 13.2 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain HrpB7 PF09486.10 GBG92470.1 - 1.7 9.1 6.0 0.94 9.8 3.2 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DDE_Tnp_4 PF13359.6 GBG92472.1 - 3.4e-25 88.5 0.0 6.5e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92472.1 - 2.2e-08 34.0 0.0 3.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92472.1 - 0.00011 21.9 1.3 0.00013 21.7 0.0 1.8 2 1 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG92474.1 - 0.00011 22.5 1.8 0.0002 21.7 1.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG92474.1 - 0.0048 16.9 0.1 0.0076 16.3 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RT_RNaseH PF17917.1 GBG92476.1 - 2.5e-22 79.2 0.0 6.8e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92476.1 - 3.8e-21 75.0 0.0 8.6e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92476.1 - 2.3e-18 66.0 0.4 5.5e-18 64.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG92476.1 - 3.2e-08 33.4 0.0 5.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG92476.1 - 7.7e-07 29.6 0.1 1.7e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92476.1 - 3.5e-05 24.4 0.1 7.2e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92476.1 - 0.00067 19.4 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92476.1 - 0.022 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG92477.1 - 2.7e-34 117.2 0.0 5.6e-34 116.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92477.1 - 1e-30 106.1 0.0 1.9e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92477.1 - 4.6e-17 61.9 0.1 8.6e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92477.1 - 7.2e-15 55.2 0.2 3.6e-14 53.0 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain DDE_Tnp_4 PF13359.6 GBG92478.1 - 2.7e-20 72.6 0.0 5.2e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92478.1 - 1.2e-09 38.1 0.0 2.9e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 Plant transposon protein ZapB PF06005.12 GBG92478.1 - 0.0096 16.3 1.7 0.052 14.0 1.1 2.2 2 0 0 2 2 2 1 Cell division protein ZapB ADIP PF11559.8 GBG92478.1 - 0.012 15.6 2.1 0.024 14.7 2.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 GBG92478.1 - 0.027 13.3 1.1 0.042 12.7 1.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF745 PF05335.13 GBG92478.1 - 0.084 12.6 1.1 0.12 12.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) NEMO PF11577.8 GBG92478.1 - 0.096 12.7 0.4 0.21 11.6 0.4 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO ATP-synt_B PF00430.18 GBG92478.1 - 0.13 12.4 3.4 0.21 11.7 3.4 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TPR_MLP1_2 PF07926.12 GBG92478.1 - 0.19 11.8 4.2 0.083 13.0 1.7 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PQQ_2 PF13360.6 GBG92479.1 - 5.2e-15 55.7 0.2 6e-08 32.5 0.4 2.2 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 GBG92479.1 - 7e-14 51.0 1.7 0.0062 16.4 0.7 4.4 4 0 0 4 4 4 4 PQQ enzyme repeat PQQ_3 PF13570.6 GBG92479.1 - 9.1e-10 38.7 19.1 6.7e-05 23.2 0.9 6.7 7 1 0 7 7 7 3 PQQ-like domain XRN_M PF17846.1 GBG92479.1 - 0.28 10.1 0.0 0.39 9.6 0.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Phi29_Phage_SSB PF17427.2 GBG92480.1 - 4.6 7.5 8.2 11 6.2 1.3 2.5 1 1 1 2 2 2 0 Phage Single-stranded DNA-binding protein RT_RNaseH PF17917.1 GBG92484.1 - 6.1e-22 77.9 0.2 1.7e-21 76.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92484.1 - 5.1e-17 61.7 0.2 1e-16 60.7 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG92484.1 - 5.2e-16 58.5 0.2 3.6e-15 55.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG92484.1 - 6.5e-07 29.2 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG92484.1 - 1.6e-06 27.8 0.1 3.7e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG92484.1 - 3.6e-05 24.3 0.0 8.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG92484.1 - 0.0066 16.6 0.0 0.033 14.4 0.0 2.3 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG92484.1 - 0.0097 16.5 0.0 0.027 15.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG92484.1 - 0.066 13.5 0.0 0.3 11.4 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein PRIMA1 PF16101.5 GBG92486.1 - 0.24 11.4 11.1 0.12 12.4 8.0 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG92486.1 - 0.58 9.6 5.3 1 8.8 5.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RVT_1 PF00078.27 GBG92488.1 - 1.7e-05 24.4 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG92488.1 - 5.3 5.1 13.4 6.9 4.8 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 GBG92491.1 - 0.0019 18.4 6.3 0.0019 18.4 6.3 3.5 3 0 0 3 3 3 2 YL1 nuclear protein Na_trans_assoc PF06512.13 GBG92491.1 - 0.2 11.9 28.7 0.028 14.7 12.8 3.4 3 0 0 3 3 3 0 Sodium ion transport-associated RT_RNaseH PF17917.1 GBG92493.1 - 3.3e-21 75.5 0.0 5.8e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92493.1 - 7.7e-21 74.0 0.0 1.7e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HSP70 PF00012.20 GBG92494.1 - 1e-160 535.9 1.1 2.6e-160 534.5 1.1 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG92494.1 - 1.1e-13 50.7 1.3 0.00012 21.0 0.1 3.2 3 0 0 3 3 3 3 MreB/Mbl protein DDR PF08841.10 GBG92494.1 - 0.02 13.9 0.3 0.25 10.3 0.0 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 GBG92494.1 - 0.1 13.1 2.8 15 6.1 0.0 4.0 3 2 0 3 3 3 0 Cell division protein FtsA TAD2 PF18521.1 GBG92495.1 - 0.065 13.2 1.9 1.5 8.9 0.0 3.4 3 0 0 3 3 3 0 Transactivation domain 2 CENP-F_leu_zip PF10473.9 GBG92495.1 - 0.1 12.6 4.8 0.05 13.6 0.8 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.9 GBG92495.1 - 9.8 4.6 10.2 34 2.8 10.0 1.9 1 1 0 1 1 1 0 Macoilin family HSP70 PF00012.20 GBG92496.1 - 5.9e-110 368.2 0.0 9e-110 367.6 0.0 1.2 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG92496.1 - 1.8e-07 30.3 0.8 0.011 14.5 0.3 3.1 2 1 0 2 2 2 2 MreB/Mbl protein StbA PF06406.11 GBG92496.1 - 0.014 14.6 0.3 0.13 11.5 0.3 2.2 1 1 0 1 1 1 0 StbA protein DUF2201_N PF13203.6 GBG92497.1 - 0.15 11.6 3.7 0.19 11.3 3.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.12 GBG92497.1 - 0.39 8.9 16.2 0.46 8.6 16.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG92497.1 - 0.67 9.3 19.5 0.81 9.1 19.5 1.1 1 0 0 1 1 1 0 SDA1 DUF4746 PF15928.5 GBG92497.1 - 1 8.8 8.8 1.3 8.4 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Lin-8 PF03353.15 GBG92497.1 - 1.2 8.6 7.7 1.5 8.3 7.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF-3c_N PF05470.12 GBG92497.1 - 5.3 5.2 9.8 6.8 4.9 9.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CobT PF06213.12 GBG92497.1 - 5.7 6.2 17.6 8.8 5.6 17.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GBG92497.1 - 6.2 5.0 13.2 7.1 4.8 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Integrase_H2C2 PF17921.1 GBG92498.1 - 1.5e-19 69.8 1.3 4.4e-19 68.3 1.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92498.1 - 2.8e-16 59.8 0.0 4.7e-15 55.8 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain DUF659 PF04937.15 GBG92498.1 - 4.8e-15 55.7 0.0 1.6e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG92498.1 - 4.4e-06 26.9 0.0 1.8e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92498.1 - 0.00025 21.0 0.0 0.00065 19.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG92498.1 - 0.014 15.6 0.2 0.039 14.2 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger DUF659 PF04937.15 GBG92499.1 - 1.2e-15 57.6 0.0 1.8e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) HSP70 PF00012.20 GBG92500.1 - 2.6e-159 531.2 0.0 3.8e-159 530.7 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG92500.1 - 5.9e-09 35.2 1.2 0.0079 15.1 0.2 3.9 3 1 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 GBG92500.1 - 0.003 18.0 0.3 39 4.7 0.0 4.1 3 1 0 3 3 3 2 Cell division protein FtsA StbA PF06406.11 GBG92500.1 - 0.0048 16.2 0.5 0.14 11.4 0.5 2.3 1 1 0 1 1 1 1 StbA protein gag-asp_proteas PF13975.6 GBG92501.1 - 4.2e-07 30.4 0.1 4.2e-07 30.4 0.1 3.0 4 1 1 5 5 5 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92501.1 - 5.7e-06 26.9 0.4 2.8e-05 24.7 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG92501.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92501.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease HSP70 PF00012.20 GBG92502.1 - 1.9e-156 521.7 0.0 3.2e-156 521.0 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG92502.1 - 8.5e-08 31.4 0.7 0.048 12.5 0.0 3.9 2 1 1 3 3 3 3 MreB/Mbl protein StbA PF06406.11 GBG92502.1 - 0.0064 15.8 0.0 0.012 14.8 0.0 1.4 1 1 0 1 1 1 1 StbA protein FGGY_C PF02782.16 GBG92502.1 - 0.021 14.5 0.0 0.077 12.7 0.0 1.9 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BNR_4 PF15892.5 GBG92502.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-containing family member DUF2057 PF09829.9 GBG92503.1 - 0.079 13.1 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Integrase_H2C2 PF17921.1 GBG92505.1 - 4.2e-08 33.2 0.1 1.1e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG92505.1 - 1.4e-06 27.9 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92506.1 - 4.6e-21 74.7 0.0 1.1e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92506.1 - 4.8e-20 71.8 0.0 1.4e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92506.1 - 6e-10 39.4 0.0 1.4e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG92506.1 - 2.4e-06 27.2 0.0 5.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG92506.1 - 2.4e-05 24.3 0.0 7.7e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG92508.1 - 0.00015 21.9 9.6 0.0062 16.8 0.0 4.6 3 2 2 5 5 5 2 Retrotransposon gag protein Use1 PF09753.9 GBG92508.1 - 1.3 8.7 13.5 0.47 10.1 10.3 1.7 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF4407 PF14362.6 GBG92508.1 - 2.1 7.6 15.8 9.8 5.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4288 PF14119.6 GBG92508.1 - 2.2 8.7 5.2 5.6 7.4 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) RVT_1 PF00078.27 GBG92509.1 - 7.5e-28 97.6 0.0 1.2e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG92509.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain APG17 PF04108.12 GBG92509.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg17 Plavaka PF18759.1 GBG92510.1 - 1.7e-19 70.2 0.1 3.4e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Plavaka transposase Peptidase_C48 PF02902.19 GBG92510.1 - 9.4e-13 48.5 2.1 1.9e-12 47.5 0.1 2.3 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain gag-asp_proteas PF13975.6 GBG92510.1 - 1.5e-07 31.9 0.1 7.6e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92510.1 - 1.3e-06 29.0 0.0 3.5e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92510.1 - 0.0013 18.5 0.2 0.0027 17.5 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92510.1 - 0.097 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4543 PF15076.6 GBG92511.1 - 0.034 14.3 0.1 0.097 12.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) zf-C2H2_6 PF13912.6 GBG92511.1 - 0.13 12.3 5.1 0.32 11.0 5.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GBG92511.1 - 0.35 11.8 4.8 1.4 10.0 4.8 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 GBG92511.1 - 4.7 7.6 10.6 1 9.7 4.0 3.1 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Iso_dh PF00180.20 GBG92513.1 - 1.4e-68 231.6 0.0 1.9e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_tail_T PF06223.12 GBG92513.1 - 0.012 16.1 0.0 0.065 13.8 0.0 2.1 1 1 1 2 2 2 0 Minor tail protein T VID27_N PF17748.1 GBG92513.1 - 0.075 12.9 4.6 0.12 12.2 4.6 1.2 1 0 0 1 1 1 0 VID27 N-terminal region DUF4746 PF15928.5 GBG92513.1 - 2 7.7 9.9 3.1 7.2 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CENP-B_dimeris PF09026.10 GBG92513.1 - 7.4 7.0 10.5 13 6.2 10.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Radial_spoke PF04712.12 GBG92513.1 - 7.7 5.3 14.1 11 4.8 14.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Proteasome PF00227.26 GBG92514.1 - 1.3e-45 155.2 0.3 1.5e-45 155.0 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit BUD22 PF09073.10 GBG92515.1 - 2.6 7.3 50.0 2.9 7.1 50.0 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG92515.1 - 4.4 5.4 50.4 6 4.9 50.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 GBG92515.1 - 5.8 6.2 47.9 6.9 5.9 47.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vfa1 PF08432.10 GBG92515.1 - 5.8 7.2 34.4 7.6 6.8 34.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 GBG92515.1 - 6.8 6.0 58.0 7.8 5.8 58.0 1.1 1 0 0 1 1 1 0 SDA1 NIF PF03031.18 GBG92516.1 - 2.1e-36 125.1 0.0 3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PPR_2 PF13041.6 GBG92517.1 - 6.3e-33 112.7 3.8 1.1e-09 38.3 0.0 6.8 5 2 2 7 7 7 4 PPR repeat family PPR_3 PF13812.6 GBG92517.1 - 1e-26 92.8 0.0 3.1e-09 36.8 0.0 6.0 4 2 3 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.20 GBG92517.1 - 1.9e-22 77.8 0.1 3.8e-05 23.7 0.0 9.7 9 0 0 9 9 9 5 PPR repeat PPR_long PF17177.4 GBG92517.1 - 4.8e-16 58.8 1.8 1.8e-06 27.5 0.0 4.1 2 1 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GBG92517.1 - 2.9e-11 42.9 0.0 0.00022 20.8 0.0 6.7 7 0 0 7 7 7 2 PPR repeat ATP13 PF12921.7 GBG92517.1 - 0.039 13.8 0.0 16 5.4 0.0 3.3 3 1 0 3 3 3 0 Mitochondrial ATPase expression TPR_14 PF13428.6 GBG92517.1 - 0.68 10.9 11.5 1.4 10.0 0.2 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 GBG92517.1 - 1.2 9.9 8.5 1.7e+02 3.0 6.3 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat RVT_1 PF00078.27 GBG92518.1 - 2.1e-26 92.8 0.1 3.5e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG92518.1 - 5.8e-09 35.8 0.0 1.3e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92518.1 - 6e-07 30.0 0.0 1.4e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92518.1 - 1.4e-05 25.5 0.0 4.2e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92518.1 - 0.023 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TAF4 PF05236.14 GBG92518.1 - 0.066 13.0 8.2 0.13 12.0 8.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RVP PF00077.20 GBG92518.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase_Tyr PF07714.17 GBG92519.1 - 9.7e-84 280.7 0.0 6.5e-34 117.4 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 GBG92519.1 - 4.1e-83 278.8 0.0 2.6e-22 79.4 0.0 6.4 6 0 0 6 6 6 6 Protein kinase domain Pkinase_fungal PF17667.1 GBG92519.1 - 3.3e-08 32.7 0.0 0.0065 15.3 0.0 3.3 3 0 0 3 3 3 3 Fungal protein kinase APH PF01636.23 GBG92519.1 - 4.3e-06 26.8 0.7 0.83 9.5 0.0 5.0 5 1 0 5 5 5 2 Phosphotransferase enzyme family Arylesterase PF01731.20 GBG92519.1 - 0.061 13.5 0.0 8.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Arylesterase Kdo PF06293.14 GBG92519.1 - 0.89 8.9 4.7 36 3.6 0.0 3.9 5 0 0 5 5 5 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 GBG92520.1 - 5.9e-96 320.7 0.0 2.7e-32 112.1 0.0 5.4 4 1 1 5 5 5 5 Protein tyrosine kinase Pkinase PF00069.25 GBG92520.1 - 5.7e-94 314.4 0.0 1.4e-28 100.0 0.0 6.6 5 2 1 6 6 6 6 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG92520.1 - 1.2e-20 73.4 0.0 1e-14 54.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92520.1 - 9.2e-16 57.7 0.0 1.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Pkinase_fungal PF17667.1 GBG92520.1 - 2.2e-12 46.5 0.0 0.013 14.3 0.0 4.0 3 1 1 4 4 4 3 Fungal protein kinase rve PF00665.26 GBG92520.1 - 5.1e-11 42.8 0.0 2.6e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GBG92520.1 - 3.8e-09 36.8 0.0 1.1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APH PF01636.23 GBG92520.1 - 7.4e-07 29.3 1.2 1 9.2 0.0 4.9 5 1 0 5 5 5 3 Phosphotransferase enzyme family zf-H2C2 PF09337.10 GBG92520.1 - 6.9e-05 23.0 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Kdo PF06293.14 GBG92520.1 - 0.036 13.4 0.2 19 4.6 0.0 3.1 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arylesterase PF01731.20 GBG92520.1 - 0.066 13.4 0.0 9.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Arylesterase YrbL-PhoP_reg PF10707.9 GBG92520.1 - 0.14 11.7 0.0 13 5.2 0.0 3.1 3 1 0 3 3 3 0 PhoP regulatory network protein YrbL Mito_fiss_reg PF05308.11 GBG92520.1 - 2.1 8.4 6.9 5.2 7.1 6.9 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2057 PF09829.9 GBG92520.1 - 4.2 7.5 6.3 9 6.4 6.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) HIP1_clath_bdg PF16515.5 GBG92522.1 - 0.00033 21.2 3.6 0.00033 21.2 3.6 2.5 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 HemX PF04375.14 GBG92522.1 - 0.012 14.9 3.5 0.012 14.9 3.5 2.3 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF489 PF04356.12 GBG92522.1 - 0.013 15.5 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF489) GNAT_acetyltr_2 PF13718.6 GBG92522.1 - 0.025 14.0 4.8 1.5 8.2 0.3 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase 2 BLOC1_2 PF10046.9 GBG92522.1 - 0.049 13.9 0.6 0.049 13.9 0.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CPG4 PF15481.6 GBG92522.1 - 0.061 14.0 0.1 0.12 13.0 0.1 1.7 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 DUF1465 PF07323.12 GBG92522.1 - 0.08 12.8 11.4 0.035 14.0 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) MDH PF02315.16 GBG92522.1 - 0.084 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit FliD_N PF02465.18 GBG92522.1 - 0.1 13.3 4.7 0.14 12.9 0.3 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ERM PF00769.19 GBG92522.1 - 0.11 12.3 18.9 0.21 11.4 3.3 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.6 GBG92522.1 - 0.12 11.0 10.0 0.15 10.7 10.0 1.0 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 GBG92522.1 - 0.19 11.2 8.9 0.25 10.9 8.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 GBG92522.1 - 0.25 11.7 17.9 0.29 11.5 0.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 GBG92522.1 - 0.31 11.2 4.3 0.072 13.3 0.8 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 GBG92522.1 - 0.42 10.7 11.3 0.092 12.8 1.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3958 PF13125.6 GBG92522.1 - 0.62 10.3 16.7 2.4 8.4 2.3 2.9 3 1 0 3 3 2 0 Protein of unknown function (DUF3958) DUF572 PF04502.13 GBG92522.1 - 0.65 9.6 9.7 0.82 9.2 9.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Gp58 PF07902.11 GBG92522.1 - 1.1 7.5 4.1 1.9 6.7 4.1 1.5 1 1 0 1 1 1 0 gp58-like protein USP8_interact PF08941.10 GBG92522.1 - 1.7 8.4 5.5 0.14 11.9 0.4 1.7 2 0 0 2 2 2 0 USP8 interacting DUF1664 PF07889.12 GBG92522.1 - 1.8 8.6 5.3 0.48 10.5 0.4 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 GBG92522.1 - 2.5 8.6 7.5 1.5 9.3 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 DivIVA PF05103.13 GBG92522.1 - 3 7.9 18.2 4.4 7.4 10.9 2.3 2 0 0 2 2 2 0 DivIVA protein Seryl_tRNA_N PF02403.22 GBG92522.1 - 3.2 8.0 10.8 5.2 7.3 0.3 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-H PF05837.12 GBG92522.1 - 3.5 8.1 15.5 0.15 12.5 3.4 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TMPIT PF07851.13 GBG92522.1 - 6.5 5.9 9.9 0.7 9.1 3.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein RVT_1 PF00078.27 GBG92523.1 - 1.1e-26 93.7 0.1 1.9e-26 92.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92523.1 - 3.4e-22 78.4 0.0 3.6e-21 75.1 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92523.1 - 7.1e-19 68.0 0.0 3.1e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG92523.1 - 5.5e-05 23.7 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92523.1 - 0.0002 21.1 0.0 0.00056 19.7 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG92523.1 - 0.00023 21.7 0.0 0.00043 20.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92523.1 - 0.0003 20.6 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG92524.1 - 1.5e-30 105.1 0.0 6.5e-16 58.2 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92524.1 - 8.4e-30 103.2 0.0 2.3e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92524.1 - 4.9e-26 91.6 0.0 8.2e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG92524.1 - 8.5e-12 44.8 0.0 2.2e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG92524.1 - 7.4e-11 42.3 0.0 3.8e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG92524.1 - 0.051 14.2 0.0 0.22 12.2 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC PF00098.23 GBG92526.1 - 5.5e-05 23.1 2.3 5.5e-05 23.1 2.3 1.8 2 0 0 2 2 2 1 Zinc knuckle NUMOD3 PF07460.11 GBG92526.1 - 0.027 14.7 0.2 0.087 13.1 0.2 1.9 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) zf-CCHC_2 PF13696.6 GBG92526.1 - 0.2 11.5 5.1 0.09 12.6 1.8 1.9 2 0 0 2 2 2 0 Zinc knuckle ThiF PF00899.21 GBG92527.1 - 6.1e-26 91.3 0.0 1.3e-25 90.2 0.0 1.5 1 1 0 1 1 1 1 ThiF family O-FucT PF10250.9 GBG92528.1 - 5.1e-13 49.4 0.0 5e-08 33.0 0.0 2.7 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase RNase_PH PF01138.21 GBG92529.1 - 1.3e-46 158.3 0.0 4.2e-23 82.3 0.0 3.5 4 0 0 4 4 4 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GBG92529.1 - 4.5e-14 52.2 0.0 1.3e-09 37.9 0.0 2.8 2 1 1 3 3 3 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 GBG92529.1 - 1.6e-11 43.8 0.0 1.4e-10 40.8 0.1 2.5 2 0 0 2 2 2 1 KH domain S1 PF00575.23 GBG92529.1 - 3.8e-11 43.2 0.2 2e-10 40.9 0.1 2.3 2 0 0 2 2 2 1 S1 RNA binding domain PNPase PF03726.14 GBG92529.1 - 7e-08 32.9 0.0 1.6e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain NPV_P10 PF05531.12 GBG92530.1 - 0.26 11.8 6.2 1.8 9.1 0.2 3.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sucrose_synth PF00862.19 GBG92531.1 - 2.7e-251 834.7 0.0 3.3e-251 834.4 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG92531.1 - 1.7e-28 99.3 0.0 2.8e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG92531.1 - 3e-10 40.6 0.0 6.9e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG92531.1 - 6.5e-05 23.2 0.0 0.00029 21.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG92531.1 - 0.00079 19.5 0.4 0.12 12.4 0.1 3.5 3 1 0 3 3 3 1 Glycosyltransferase Family 4 Pox_D5 PF03288.16 GBG92531.1 - 0.052 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like Myb_DNA-bind_4 PF13837.6 GBG92533.1 - 9.4e-11 42.0 2.5 1.3e-10 41.5 0.9 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG92533.1 - 0.0031 17.6 2.8 0.0038 17.3 1.5 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG92533.1 - 0.0052 17.1 0.5 0.011 16.0 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Sucrose_synth PF00862.19 GBG92534.1 - 1.1e-249 829.4 0.0 1.4e-249 829.0 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG92534.1 - 4.3e-28 98.0 0.2 2.1e-27 95.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG92534.1 - 5.3e-10 39.8 0.0 1.3e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG92534.1 - 0.00036 20.9 0.0 0.00036 20.9 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG92534.1 - 0.0029 17.6 0.1 0.13 12.3 0.1 2.8 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Pox_D5 PF03288.16 GBG92534.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 Poxvirus D5 protein-like RVT_1 PF00078.27 GBG92535.1 - 1.3e-05 24.8 0.0 0.00057 19.5 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG92535.1 - 0.0027 17.9 0.1 0.027 14.7 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein ANAPC_CDC26 PF10471.9 GBG92535.1 - 1.5 9.7 5.4 8 7.4 1.9 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Sucrose_synth PF00862.19 GBG92536.1 - 1.8e-251 835.2 0.0 2.2e-251 835.0 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 GBG92536.1 - 1.7e-28 99.3 0.0 2.8e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG92536.1 - 3e-10 40.6 0.0 6.9e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GBG92536.1 - 6.6e-05 23.2 0.0 0.00029 21.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GBG92536.1 - 0.00079 19.5 0.4 0.12 12.4 0.1 3.5 3 1 0 3 3 3 1 Glycosyltransferase Family 4 Pox_D5 PF03288.16 GBG92536.1 - 0.051 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like SDA1 PF05285.12 GBG92537.1 - 0.17 11.3 14.5 0.23 10.9 14.5 1.1 1 0 0 1 1 1 0 SDA1 rve PF00665.26 GBG92540.1 - 3.8e-12 46.5 0.0 7.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG92540.1 - 5.4e-06 26.1 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG92540.1 - 0.003 17.3 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Ndc80_HEC PF03801.13 GBG92541.1 - 4.7e-40 136.7 0.0 1.3e-39 135.3 0.0 1.7 2 0 0 2 2 2 1 HEC/Ndc80p family DUF2508 PF10704.9 GBG92541.1 - 0.0068 16.6 0.9 0.0068 16.6 0.9 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2508) DUF5343 PF17278.2 GBG92541.1 - 0.067 13.3 0.3 0.28 11.3 0.3 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5343) Tox-REase-5 PF15648.6 GBG92541.1 - 0.13 12.8 2.7 0.87 10.1 0.2 2.7 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 Integrase_H2C2 PF17921.1 GBG92542.1 - 9.6e-14 51.2 0.6 2.1e-13 50.1 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92542.1 - 1.8e-11 44.3 0.0 5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG92542.1 - 3.7e-06 26.6 0.0 6.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG92542.1 - 4.5e-06 27.1 0.1 2.6e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92542.1 - 3.6e-05 24.3 0.1 0.00023 21.7 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG92542.1 - 0.025 14.4 0.1 0.065 13.0 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG92542.1 - 0.039 14.2 0.7 0.094 13.0 0.7 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Ribosomal_60s PF00428.19 GBG92542.1 - 0.47 11.1 2.5 4.3 8.0 2.5 2.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein RT_RNaseH_2 PF17919.1 GBG92543.1 - 6.9e-23 80.6 0.0 1.6e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92543.1 - 3e-21 75.7 0.0 3.4e-20 72.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92543.1 - 3.1e-13 49.6 0.1 1.8e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG92543.1 - 1.6e-10 41.2 0.0 3.8e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG92543.1 - 0.00059 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF563 PF04577.14 GBG92544.1 - 1.3e-18 67.9 0.0 2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) LisH PF08513.11 GBG92544.1 - 0.017 15.1 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 LisH CofC PF01983.16 GBG92544.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Guanylyl transferase CofC like RVT_1 PF00078.27 GBG92545.1 - 2.9e-36 125.0 0.1 5.4e-36 124.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92545.1 - 1.2e-28 99.5 0.3 5.2e-28 97.4 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92545.1 - 4.7e-28 97.2 0.0 3e-27 94.6 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4392 PF14336.6 GBG92545.1 - 0.17 11.3 1.2 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Phage_GPO PF05929.11 GBG92545.1 - 0.32 10.6 0.0 0.32 10.6 0.0 3.2 2 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase REV PF00424.18 GBG92545.1 - 2.4 8.2 4.8 5.1 7.2 0.5 3.0 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) RT_RNaseH_2 PF17919.1 GBG92546.1 - 6.5e-30 103.1 0.0 1e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92546.1 - 1.5e-28 99.1 0.0 2.3e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92546.1 - 6.9e-15 55.2 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG92546.1 - 0.013 15.3 0.1 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Lipocalin_2 PF08212.12 GBG92548.1 - 0.0012 18.8 0.0 0.28 11.1 0.0 3.0 3 0 0 3 3 3 2 Lipocalin-like domain Cnn_1N PF07989.11 GBG92549.1 - 0.35 11.0 4.3 1.1 9.4 0.8 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Zip PF02535.22 GBG92549.1 - 3.4 6.8 5.0 3.2 6.9 3.5 1.6 1 1 1 2 2 2 0 ZIP Zinc transporter GIY-YIG PF01541.24 GBG92550.1 - 6.7e-07 29.5 0.0 3.3e-06 27.3 0.0 2.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain RVT_1 PF00078.27 GBG92550.1 - 0.0046 16.5 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_1c PF00749.21 GBG92550.1 - 0.14 11.0 5.8 0.33 9.8 5.8 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain SAP PF02037.27 GBG92550.1 - 0.15 11.8 0.6 0.58 10.0 0.0 2.4 2 0 0 2 2 2 0 SAP domain FemAB_like PF04339.12 GBG92550.1 - 1.7 7.7 4.8 3.3 6.8 4.8 1.3 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition FlxA PF14282.6 GBG92550.1 - 6.7 6.8 11.6 13 5.8 11.6 1.5 1 0 0 1 1 1 0 FlxA-like protein RVT_1 PF00078.27 GBG92551.1 - 9.8e-29 100.4 0.0 1.7e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG92551.1 - 4.6e-10 39.3 0.0 1.2e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG92551.1 - 8.8e-08 32.4 0.0 2.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG92551.1 - 0.001 19.6 0.0 0.0033 18.0 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Connexin PF00029.19 GBG92552.1 - 4.2 7.1 12.2 1.2 8.9 4.0 2.3 2 0 0 2 2 2 0 Connexin Med19 PF10278.9 GBG92552.1 - 8.4 6.3 45.6 1.9 8.4 11.2 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Presenilin PF01080.17 GBG92553.1 - 0.7 8.6 25.5 0.77 8.5 25.5 1.1 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 GBG92553.1 - 1.1 8.0 17.1 1.1 8.0 17.1 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Membralin PF09746.9 GBG92553.1 - 2.9 6.8 9.5 3.2 6.7 9.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein NPR3 PF03666.13 GBG92553.1 - 3 6.6 20.8 4.3 6.0 20.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5427 PF10310.9 GBG92553.1 - 4.8 6.0 27.6 5.9 5.7 27.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) AAA_11 PF13086.6 GBG92553.1 - 5.5 6.7 18.0 6.7 6.4 18.0 1.3 1 0 0 1 1 1 0 AAA domain Apt1 PF10351.9 GBG92553.1 - 6.1 5.6 15.2 6.7 5.5 15.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4045 PF13254.6 GBG92553.1 - 8.3 5.9 21.7 9.3 5.8 21.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM216B PF15107.6 GBG92554.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 FAM216B protein family FlaC_arch PF05377.11 GBG92554.1 - 0.64 10.5 5.6 1 9.8 0.2 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4156 PF13698.6 GBG92554.1 - 4.4 7.7 6.3 10 6.6 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4156) SPT2 PF08243.11 GBG92555.1 - 1.5e-12 48.0 36.2 1.5e-12 48.0 36.2 3.5 3 2 1 4 4 4 1 SPT2 chromatin protein DNA_pol_phi PF04931.13 GBG92555.1 - 0.83 7.7 19.0 1.5 6.9 19.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pectinesterase PF01095.19 GBG92557.1 - 1.5e-75 253.7 0.3 1.9e-75 253.4 0.3 1.1 1 0 0 1 1 1 1 Pectinesterase DUF659 PF04937.15 GBG92559.1 - 5e-20 71.9 0.0 9.9e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf_C2H2_6 PF18450.1 GBG92559.1 - 0.096 12.4 0.5 0.26 11.0 0.5 1.7 1 0 0 1 1 1 0 Zinc Finger domain Sirohm_synth_C PF14823.6 GBG92559.1 - 0.17 11.5 0.9 1 9.0 0.1 2.2 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Retrotrans_gag PF03732.17 GBG92560.1 - 0.0016 18.6 0.2 0.0016 18.6 0.2 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein Lipin_mid PF16876.5 GBG92560.1 - 0.0035 17.4 0.4 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain PDEase_II PF02112.15 GBG92560.1 - 0.054 12.6 0.3 0.084 12.0 0.3 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II LD_cluster2 PF18163.1 GBG92560.1 - 0.12 11.9 0.3 0.23 10.9 0.3 1.4 1 0 0 1 1 1 0 SLOG cluster2 RVT_1 PF00078.27 GBG92561.1 - 7.8e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG92561.1 - 0.0002 21.3 3.1 0.00042 20.3 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92561.1 - 0.014 15.2 4.3 0.03 14.1 4.3 1.6 1 0 0 1 1 1 0 Zinc knuckle WD40 PF00400.32 GBG92562.1 - 2.4e-07 31.3 11.6 0.0065 17.3 0.4 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG92562.1 - 8.7e-07 29.2 0.4 1.4 9.2 0.0 5.1 3 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain tify PF06200.14 GBG92562.1 - 1.7 8.0 3.1 32 4.0 1.2 2.4 2 0 0 2 2 2 0 tify domain Integrase_H2C2 PF17921.1 GBG92563.1 - 1.3e-13 50.9 0.1 2.8e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG92563.1 - 1.4e-06 28.8 0.0 2.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG92563.1 - 2.3e-05 24.6 0.0 5.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG92563.1 - 0.0015 19.1 0.0 0.003 18.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG92563.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG92563.1 - 0.042 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 GBG92563.1 - 0.18 11.6 0.4 0.34 10.7 0.4 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG92564.1 - 1.1e-28 100.2 0.1 1.8e-28 99.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92564.1 - 3.7e-19 69.0 0.0 7.9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92564.1 - 9.2e-16 57.7 0.6 3.3e-15 55.9 0.1 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 GBG92564.1 - 1.7e-12 47.0 0.0 3.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 GBG92564.1 - 1.7e-10 40.8 0.0 3.7e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG92564.1 - 0.00024 21.2 0.1 0.00066 19.8 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger TFIIF_alpha PF05793.12 GBG92565.1 - 1.2e-05 24.2 65.8 1.2e-05 24.2 65.8 3.0 3 0 0 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SURF2 PF05477.11 GBG92566.1 - 0.25 11.0 4.2 0.44 10.2 4.2 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 GBG92567.1 - 0.28 9.4 6.7 0.48 8.7 6.7 1.3 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 GBG92568.1 - 0.33 10.6 7.4 0.29 10.8 5.3 1.9 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 GBG92569.1 - 0.69 8.1 6.3 1.1 7.4 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 GBG92569.1 - 1.5 8.7 7.0 0.53 10.2 0.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TelA PF05816.11 GBG92571.1 - 0.0076 15.4 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) SURF2 PF05477.11 GBG92571.1 - 0.015 15.0 0.5 0.015 15.0 0.5 3.5 2 1 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 GBG92571.1 - 1.3 7.1 55.0 0.088 11.0 44.0 2.2 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 GBG92572.1 - 0.046 12.0 7.7 0.075 11.3 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein gag-asp_proteas PF13975.6 GBG92573.1 - 0.00013 22.4 0.1 0.00041 20.9 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92573.1 - 0.006 16.4 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG92573.1 - 0.0062 17.2 0.1 0.02 15.5 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A3 PF02160.15 GBG92573.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) zf-CCHC PF00098.23 GBG92573.1 - 0.49 10.6 1.9 1 9.6 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG92574.1 - 3.2e-05 24.4 0.1 7.4e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92574.1 - 0.0015 19.1 0.1 0.0035 17.9 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92574.1 - 0.11 12.3 0.2 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 Aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG92574.1 - 0.13 11.9 0.2 0.26 11.0 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG92574.1 - 0.47 10.6 1.7 0.79 9.9 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF659 PF04937.15 GBG92576.1 - 3.3e-21 75.7 0.0 5.7e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG92577.1 - 3.5e-22 78.3 0.0 5.8e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92577.1 - 1.3e-16 60.8 0.0 2.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92577.1 - 3.7e-08 33.2 0.1 6e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG92578.1 - 1.1e-27 96.7 0.1 1.8e-27 96.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92578.1 - 0.00057 19.6 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ASFV_J13L PF05568.11 GBG92578.1 - 0.23 11.2 3.9 0.39 10.5 3.9 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein RAP1 PF07218.11 GBG92578.1 - 7.2 4.8 13.8 10 4.3 13.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ceramidase PF05875.12 GBG92579.1 - 0.55 9.6 2.7 0.41 10.0 0.3 1.8 2 0 0 2 2 2 0 Ceramidase Nop25 PF09805.9 GBG92579.1 - 1.3 9.5 13.0 14 6.1 0.2 3.5 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) SRP54_N PF02881.19 GBG92580.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain H_PPase PF03030.16 GBG92581.1 - 1.6e-250 833.3 37.2 1.8e-250 833.1 37.2 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Topo_Zn_Ribbon PF08272.11 GBG92582.1 - 0.07 12.8 0.3 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Arm PF00514.23 GBG92583.1 - 1.8e-12 46.8 15.0 0.04 14.0 0.4 7.9 6 1 1 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GBG92583.1 - 1.1e-07 31.5 15.5 0.2 12.0 0.2 7.0 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 GBG92583.1 - 2.9e-07 30.7 6.6 0.0012 18.9 0.8 3.0 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GBG92583.1 - 1.7e-06 28.3 8.3 0.0013 19.0 0.2 5.1 3 2 2 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 GBG92583.1 - 0.0043 17.6 0.5 1.2 9.8 0.3 2.8 3 0 0 3 3 2 1 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 GBG92583.1 - 0.0053 16.9 2.3 1.9 8.6 0.2 3.3 3 1 0 3 3 3 1 V-ATPase subunit H Adaptin_N PF01602.20 GBG92583.1 - 0.0065 15.1 4.5 0.57 8.7 0.2 3.0 2 1 1 3 3 3 3 Adaptin N terminal region Proteasom_PSMB PF10508.9 GBG92583.1 - 0.046 12.2 8.7 0.69 8.3 1.3 2.7 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Atx10homo_assoc PF09759.9 GBG92583.1 - 0.057 13.5 0.6 0.79 9.8 0.1 3.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 GBG92583.1 - 0.057 13.4 4.0 0.21 11.5 0.5 2.8 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central E3_UbLigase_R4 PF13764.6 GBG92583.1 - 0.076 11.2 2.1 0.11 10.6 0.1 2.0 2 1 1 3 3 3 0 E3 ubiquitin-protein ligase UBR4 RIX1 PF08167.12 GBG92583.1 - 0.093 12.5 0.6 0.4 10.4 0.1 2.3 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 GBG92583.1 - 0.11 13.0 10.9 1.9 9.1 0.4 5.1 5 1 0 5 5 5 0 HEAT-like repeat HTH_18 PF12833.7 GBG92583.1 - 0.11 12.8 0.5 5.8 7.3 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain WAPL PF07814.13 GBG92583.1 - 0.42 9.4 7.2 0.051 12.4 1.7 2.1 2 1 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin RasGEF_N_2 PF14663.6 GBG92583.1 - 0.42 11.0 7.5 12 6.3 0.4 4.1 2 2 2 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SPACA9 PF15120.6 GBG92583.1 - 3.7 7.3 6.5 7.5 6.3 0.3 3.0 2 2 0 3 3 3 0 Sperm acrosome-associated protein 9 rve PF00665.26 GBG92584.1 - 1.2e-06 28.7 0.0 2.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 GBG92584.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain 5_3_exonuc_N PF02739.16 GBG92585.1 - 3.4e-09 36.8 0.0 6.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 GBG92585.1 - 2.1e-08 34.6 0.0 4.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Vps54_N PF10475.9 GBG92586.1 - 1.5e-10 40.8 0.0 2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex rve PF00665.26 GBG92587.1 - 2e-16 60.3 0.1 8.1e-14 51.8 0.0 2.9 3 0 0 3 3 3 2 Integrase core domain GvpL_GvpF PF06386.11 GBG92587.1 - 0.19 11.6 5.6 0.054 13.4 1.6 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF5523 PF17661.1 GBG92589.1 - 0.0036 17.0 17.2 0.0041 16.8 17.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5523) Na_trans_assoc PF06512.13 GBG92589.1 - 0.0092 16.3 8.3 0.012 15.9 8.3 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated PTPRCAP PF15713.5 GBG92589.1 - 0.0096 16.2 21.6 0.013 15.8 21.6 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Paf1 PF03985.13 GBG92589.1 - 0.02 13.9 23.3 0.023 13.7 23.3 1.0 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.14 GBG92589.1 - 0.031 14.1 21.1 0.047 13.5 21.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.10 GBG92589.1 - 0.031 13.6 17.0 0.036 13.4 17.0 1.2 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 GBG92589.1 - 0.068 13.2 16.5 0.075 13.0 16.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 GBG92589.1 - 0.28 9.3 22.9 0.33 9.1 22.9 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 GBG92589.1 - 0.49 9.9 24.4 0.56 9.7 24.4 1.0 1 0 0 1 1 1 0 PPP4R2 Drc1-Sld2 PF11719.8 GBG92589.1 - 0.61 9.6 22.7 0.77 9.2 22.7 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF5427 PF10310.9 GBG92589.1 - 0.65 8.9 13.1 0.75 8.7 13.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CDC27 PF09507.10 GBG92589.1 - 0.74 9.1 18.1 0.84 9.0 18.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Neur_chan_memb PF02932.16 GBG92589.1 - 0.76 9.8 2.6 0.84 9.7 2.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spem1 PF15670.5 GBG92589.1 - 1.8 8.1 9.0 2.1 7.9 9.0 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 MDM1 PF15501.6 GBG92589.1 - 2.7 7.1 19.2 3.1 6.9 19.2 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Presenilin PF01080.17 GBG92589.1 - 2.7 6.6 13.0 3 6.5 13.0 1.0 1 0 0 1 1 1 0 Presenilin TFB6 PF17110.5 GBG92589.1 - 2.9 7.6 12.4 3.7 7.3 12.4 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Zip PF02535.22 GBG92589.1 - 3.2 6.9 7.8 3.4 6.8 7.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 GBG92589.1 - 3.5 6.3 18.6 4.4 6.0 18.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 GBG92589.1 - 4.2 6.7 22.8 5.2 6.4 22.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT LAP1C PF05609.12 GBG92589.1 - 4.2 6.3 10.9 5 6.1 10.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Sec62 PF03839.16 GBG92589.1 - 5.1 6.5 9.7 6.4 6.2 9.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 MRNIP PF15749.5 GBG92589.1 - 5.7 7.7 12.1 7.8 7.3 12.1 1.3 1 0 0 1 1 1 0 MRN-interacting protein DUF913 PF06025.12 GBG92589.1 - 6.2 5.7 10.3 6.4 5.6 10.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Usp PF00582.26 GBG92589.1 - 6.4 7.3 7.5 9.1 6.8 7.5 1.4 1 0 0 1 1 1 0 Universal stress protein family Vfa1 PF08432.10 GBG92589.1 - 7 6.9 18.6 9.1 6.6 18.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.6 GBG92589.1 - 7.9 6.4 12.1 9.5 6.2 12.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 GBG92589.1 - 8.4 6.1 18.8 10 5.8 18.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.16 GBG92589.1 - 9.1 5.4 15.5 12 5.0 15.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-CCHC PF00098.23 GBG92590.1 - 6.8e-05 22.8 2.0 6.8e-05 22.8 2.0 2.5 3 0 0 3 3 3 1 Zinc knuckle Atx10homo_assoc PF09759.9 GBG92590.1 - 0.12 12.4 0.1 0.43 10.6 0.1 1.9 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain SDA1 PF05285.12 GBG92592.1 - 0.12 11.8 13.1 0.2 11.0 13.1 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG92592.1 - 0.46 8.7 15.7 0.66 8.1 15.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG92592.1 - 4.6 5.4 12.6 7.4 4.7 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein BCNT PF07572.12 GBG92593.1 - 1.4e-23 82.7 4.7 1.4e-23 82.7 4.7 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development RVT_1 PF00078.27 GBG92595.1 - 2.3e-15 56.7 0.0 4e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 GBG92595.1 - 2.6e-11 43.3 0.0 6.2e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG92595.1 - 1.6e-07 31.5 0.0 4.3e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF4399 PF14347.6 GBG92595.1 - 0.084 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) PTPRCAP PF15713.5 GBG92597.1 - 0.014 15.6 11.1 0.021 15.1 11.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 GBG92597.1 - 0.022 13.6 2.9 0.027 13.3 2.9 1.1 1 0 0 1 1 1 0 Presenilin Sporozoite_P67 PF05642.11 GBG92597.1 - 0.056 11.5 3.4 0.065 11.3 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC27 PF09507.10 GBG92597.1 - 0.076 12.4 16.5 0.1 12.0 16.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 GBG92597.1 - 0.63 8.3 16.0 0.84 7.8 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C37 PF05416.12 GBG92597.1 - 1.3 7.5 6.1 1.7 7.1 6.1 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Raftlin PF15250.6 GBG92597.1 - 2 7.1 5.6 2.6 6.7 5.6 1.1 1 0 0 1 1 1 0 Raftlin Menin PF05053.13 GBG92597.1 - 2 6.7 3.7 2.6 6.3 3.7 1.1 1 0 0 1 1 1 0 Menin Hid1 PF12722.7 GBG92597.1 - 2.6 6.1 8.8 3.5 5.6 8.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2052 PF09747.9 GBG92597.1 - 3.6 7.7 18.7 6 6.9 18.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) HSP90 PF00183.18 GBG92597.1 - 4.3 6.1 14.1 5.6 5.7 14.1 1.1 1 0 0 1 1 1 0 Hsp90 protein RRN3 PF05327.11 GBG92597.1 - 4.6 5.7 5.8 5.6 5.4 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GBG92597.1 - 6 4.8 17.2 7.9 4.4 17.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GBG92597.1 - 6.3 4.9 18.5 11 4.0 18.5 1.3 1 0 0 1 1 1 0 Nop14-like family DUF3138 PF11336.8 GBG92598.1 - 0.41 9.2 5.2 0.61 8.6 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CDC45 PF02724.14 GBG92600.1 - 0.049 11.9 9.3 0.049 11.9 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG92600.1 - 0.081 11.1 13.9 0.084 11.1 13.9 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 GBG92600.1 - 0.18 11.1 11.0 0.24 10.8 11.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 GBG92600.1 - 0.23 9.5 17.9 0.27 9.3 17.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4637 PF15470.6 GBG92600.1 - 1.7 8.3 12.2 2.6 7.7 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2457 PF10446.9 GBG92600.1 - 2.7 7.1 21.5 3.7 6.6 21.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Oleosin PF01277.17 GBG92601.1 - 0.051 13.3 13.7 0.11 12.2 13.7 1.6 1 1 0 1 1 1 0 Oleosin RVP_2 PF08284.11 GBG92602.1 - 7.2e-08 32.3 0.0 1.8e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 GBG92602.1 - 6.5e-07 29.1 0.2 1e-05 25.2 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG92602.1 - 7.1e-07 29.8 0.0 1.7e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92602.1 - 3.6e-06 27.5 0.0 8.9e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG92602.1 - 0.00016 21.9 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein SbmA_BacA PF05992.12 GBG92603.1 - 0.042 13.3 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 SbmA/BacA-like family Oleosin PF01277.17 GBG92604.1 - 6.6e-06 25.9 7.3 1.4e-05 24.8 7.3 1.5 1 1 0 1 1 1 1 Oleosin DUF4381 PF14316.6 GBG92604.1 - 0.47 10.7 0.0 0.47 10.7 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) RT_RNaseH PF17917.1 GBG92605.1 - 3.4e-24 85.1 0.0 7.9e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92605.1 - 8e-23 80.4 0.0 1.8e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92605.1 - 4.3e-18 65.2 0.3 9.4e-18 64.1 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DEAD PF00270.29 GBG92605.1 - 4.9e-18 65.5 0.4 9.4e-18 64.6 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase rve PF00665.26 GBG92605.1 - 5.3e-12 46.0 0.0 1.3e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG92605.1 - 8.3e-08 32.0 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRCF PF03461.15 GBG92605.1 - 2.2e-06 27.9 0.0 8e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 TRCF domain ResIII PF04851.15 GBG92605.1 - 5.6e-06 26.5 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-H2C2 PF09337.10 GBG92605.1 - 0.0018 18.5 0.1 0.004 17.3 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger 2OG-FeII_Oxy PF03171.20 GBG92606.1 - 0.0014 19.1 0.0 0.0042 17.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5368 PF17336.2 GBG92607.1 - 0.097 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5368) BUD22 PF09073.10 GBG92608.1 - 0.5 9.7 19.8 0.56 9.5 19.8 1.0 1 0 0 1 1 1 0 BUD22 Myb_DNA-bind_4 PF13837.6 GBG92610.1 - 2.5e-05 24.6 5.8 5.3e-05 23.5 3.4 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG92610.1 - 0.14 12.4 2.8 0.19 12.0 0.7 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like T2SSM PF04612.12 GBG92610.1 - 0.79 9.8 3.8 0.32 11.1 0.3 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DDE_Tnp_4 PF13359.6 GBG92611.1 - 1.2e-08 34.8 0.0 6e-08 32.5 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92611.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein WD40 PF00400.32 GBG92612.1 - 4.7e-17 62.1 1.3 0.00034 21.4 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG92612.1 - 0.00047 20.4 0.0 1.8 8.9 0.1 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 GBG92613.1 - 3.2e-47 160.9 0.0 3.2e-24 85.7 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92613.1 - 2e-24 85.5 0.0 7.2e-24 83.7 0.0 2.0 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92613.1 - 3.7e-22 78.6 0.0 7.7e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92613.1 - 2.5e-09 37.1 0.7 1.3e-08 34.8 0.2 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG92613.1 - 2.1e-08 34.6 0.0 4.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92613.1 - 3e-08 34.2 0.0 7.7e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92613.1 - 2.5e-07 30.6 0.0 5.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG92613.1 - 9e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Trans_reg_C PF00486.28 GBG92613.1 - 0.0039 17.2 1.2 3.9 7.6 0.1 2.7 2 0 0 2 2 2 2 Transcriptional regulatory protein, C terminal APG17 PF04108.12 GBG92613.1 - 0.004 16.3 0.2 3.6 6.6 0.0 2.8 2 1 1 3 3 3 2 Autophagy protein Apg17 DUF5491 PF17595.2 GBG92613.1 - 0.028 14.7 0.0 5 7.5 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5491) SLIDE PF09111.10 GBG92613.1 - 0.13 12.3 0.1 27 4.8 0.0 2.6 2 0 0 2 2 2 0 SLIDE His_kinase PF06580.13 GBG92613.1 - 0.17 12.2 1.5 27 5.2 0.1 2.8 3 0 0 3 3 2 0 Histidine kinase DUF659 PF04937.15 GBG92615.1 - 1.8e-33 115.5 0.0 1.5e-23 83.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) DSS1_SEM1 PF05160.13 GBG92615.1 - 0.012 15.6 7.4 2.2 8.4 3.9 3.2 2 0 0 2 2 2 0 DSS1/SEM1 family RT_RNaseH PF17917.1 GBG92617.1 - 5.2e-24 84.6 0.0 1e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92617.1 - 2.4e-23 82.1 0.0 4.2e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92617.1 - 1.6e-09 37.7 0.6 6.2e-09 35.7 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG92617.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 gag-asp_proteas PF13975.6 GBG92617.1 - 0.024 15.2 0.0 0.055 14.0 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92617.1 - 0.095 13.4 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Troponin PF00992.20 GBG92618.1 - 0.79 10.0 11.9 5.8 7.2 12.0 2.1 1 1 0 1 1 1 0 Troponin DUF3138 PF11336.8 GBG92620.1 - 0.11 11.0 2.8 0.2 10.2 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) REV PF00424.18 GBG92620.1 - 0.82 9.7 6.1 0.64 10.1 1.0 2.5 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF3500 PF12006.8 GBG92620.1 - 0.99 8.8 4.2 1.7 8.1 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) DUF659 PF04937.15 GBG92621.1 - 8.4e-15 54.9 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CMD PF02627.20 GBG92622.1 - 0.24 11.5 2.2 0.55 10.3 2.1 1.6 1 1 0 1 1 1 0 Carboxymuconolactone decarboxylase family RVT_1 PF00078.27 GBG92625.1 - 2.3e-25 89.4 0.0 3.6e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92625.1 - 6.8e-19 67.8 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92625.1 - 2.1e-09 37.6 0.0 4.8e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG92625.1 - 4.2e-06 27.2 0.0 7.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92625.1 - 9.2e-06 26.2 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92625.1 - 1.2e-05 25.1 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG92625.1 - 0.00071 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF659 PF04937.15 GBG92627.1 - 2.5e-18 66.4 0.0 3.5e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Asp_protease_2 PF13650.6 GBG92631.1 - 6.1e-07 30.0 0.1 1.4e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92631.1 - 3.8e-05 24.2 0.1 8.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Pkinase_Tyr PF07714.17 GBG92634.1 - 5.7e-75 251.9 0.0 1.9e-36 125.7 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GBG92634.1 - 7.5e-69 232.0 0.0 5.9e-33 114.4 0.0 3.0 2 2 0 2 2 2 2 Protein kinase domain APH PF01636.23 GBG92634.1 - 1.2e-06 28.6 0.0 0.067 13.1 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family PRIMA1 PF16101.5 GBG92634.1 - 0.0013 18.7 4.1 0.11 12.5 0.6 2.5 2 0 0 2 2 2 2 Proline-rich membrane anchor 1 Pkinase_fungal PF17667.1 GBG92634.1 - 0.0044 15.8 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase eIF-3c_N PF05470.12 GBG92634.1 - 2.9 6.1 6.4 4.9 5.3 6.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3519 PF12033.8 GBG92634.1 - 7.3 7.0 12.4 2.7 8.4 3.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) Myb_DNA-bind_4 PF13837.6 GBG92636.1 - 0.0001 22.6 2.5 0.00012 22.4 0.5 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF1635 PF07795.11 GBG92636.1 - 0.014 15.3 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) MADF_DNA_bdg PF10545.9 GBG92636.1 - 0.16 12.3 1.0 0.44 10.9 0.1 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PIEZO PF15917.5 GBG92636.1 - 0.24 10.9 2.4 0.35 10.3 0.2 2.0 2 0 0 2 2 2 0 Piezo LSM PF01423.22 GBG92637.1 - 4.5e-10 39.1 0.1 5.5e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain RVP_2 PF08284.11 GBG92638.1 - 6.2e-10 39.0 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92638.1 - 1.9e-08 34.8 0.0 4.8e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG92638.1 - 7.4e-07 28.9 0.1 1.2e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG92638.1 - 1e-06 29.2 0.0 2.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92638.1 - 0.0018 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG92639.1 - 2.8e-40 136.4 0.0 2.6e-22 78.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92639.1 - 2.5e-32 112.2 0.0 4.5e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92639.1 - 2.2e-26 92.2 0.0 1.8e-19 70.0 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG92640.1 - 1.1e-07 31.7 0.0 4.3e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92640.1 - 8.3e-05 23.2 0.0 0.00036 21.1 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92640.1 - 0.0063 17.0 0.1 0.022 15.3 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Spc29 PF17082.5 GBG92640.1 - 0.023 14.6 0.3 0.039 13.8 0.3 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Asp_protease PF09668.10 GBG92640.1 - 0.038 13.8 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Thg1 PF04446.12 GBG92640.1 - 0.04 13.9 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 tRNAHis guanylyltransferase DUF1664 PF07889.12 GBG92640.1 - 0.14 12.2 1.0 0.33 11.0 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 GBG92640.1 - 0.21 11.7 5.6 0.28 11.3 3.7 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation Baculo_PEP_C PF04513.12 GBG92640.1 - 0.36 10.9 5.2 0.71 9.9 5.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RT_RNaseH_2 PF17919.1 GBG92641.1 - 1.3e-33 115.0 0.0 4.5e-33 113.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92641.1 - 9.8e-29 99.7 0.1 2.3e-28 98.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC_3 PF13917.6 GBG92641.1 - 0.00034 20.5 1.2 0.00089 19.2 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 GBG92641.1 - 0.03 14.6 0.1 0.083 13.2 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF3863 PF12979.7 GBG92641.1 - 0.13 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Beta_helix PF13229.6 GBG92642.1 - 8.8e-09 35.4 0.0 4.6e-07 29.8 0.0 2.1 1 1 1 2 2 2 2 Right handed beta helix region ATP-synt_F PF01990.17 GBG92643.1 - 0.039 14.3 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit tRNA-synt_1 PF00133.22 GBG92644.1 - 3.8e-49 167.5 0.1 2.6e-32 111.8 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GBG92644.1 - 2.3e-06 26.6 0.1 6.2e-05 21.9 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) Aminoglyc_resit PF10706.9 GBG92645.1 - 0.074 12.8 1.1 0.23 11.2 0.1 2.2 3 0 0 3 3 3 0 Aminoglycoside-2''-adenylyltransferase TCTP PF00838.17 GBG92646.1 - 0.14 12.5 0.2 0.27 11.5 0.2 1.5 1 0 0 1 1 1 0 Translationally controlled tumour protein RT_RNaseH_2 PF17919.1 GBG92647.1 - 5.6e-33 113.0 0.0 1.4e-32 111.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92647.1 - 3.3e-29 101.2 0.0 1.3e-28 99.3 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92647.1 - 3e-25 89.0 0.0 5.1e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG92647.1 - 1.7e-16 60.0 0.3 3.6e-16 59.0 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG92647.1 - 5.7e-14 52.1 0.0 1.2e-05 25.1 0.0 3.3 3 0 0 3 3 3 2 Retroviral aspartyl protease Asp_protease PF09668.10 GBG92647.1 - 1.8e-10 40.7 0.1 0.00043 20.1 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease Asp_protease_2 PF13650.6 GBG92647.1 - 6.8e-09 36.2 0.0 0.00043 20.9 0.0 3.2 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GBG92647.1 - 1.8e-08 34.8 0.0 0.0015 19.1 0.0 3.1 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG92647.1 - 0.00027 21.1 0.0 0.0017 18.6 0.0 2.4 2 1 0 2 2 2 1 Integrase core domain CCD48 PF15799.5 GBG92647.1 - 0.0052 15.2 7.9 0.17 10.1 0.8 2.5 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 48 XhlA PF10779.9 GBG92647.1 - 0.0064 16.7 5.5 5 7.4 0.1 3.6 3 0 0 3 3 3 1 Haemolysin XhlA Fascin PF06268.13 GBG92647.1 - 0.018 15.2 0.1 6.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Fascin domain bZIP_1 PF00170.21 GBG92647.1 - 0.02 15.0 10.2 4.7 7.4 0.4 3.8 3 0 0 3 3 3 0 bZIP transcription factor DUF2385 PF09539.10 GBG92647.1 - 0.022 15.3 1.6 6.8 7.3 0.0 4.6 5 0 0 5 5 4 0 Protein of unknown function (DUF2385) Retrotrans_gag PF03732.17 GBG92647.1 - 0.049 13.9 0.1 0.33 11.3 0.0 2.6 2 0 0 2 2 1 0 Retrotransposon gag protein DMPK_coil PF08826.10 GBG92647.1 - 0.068 13.3 6.1 0.56 10.4 0.5 3.2 2 0 0 2 2 2 0 DMPK coiled coil domain like Snapin_Pallidin PF14712.6 GBG92647.1 - 0.1 13.1 0.1 0.1 13.1 0.1 3.6 3 0 0 3 3 3 0 Snapin/Pallidin DUF4939 PF16297.5 GBG92647.1 - 0.12 12.2 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) SlyX PF04102.12 GBG92647.1 - 0.49 11.1 7.6 24 5.7 0.0 4.5 4 0 0 4 4 3 0 SlyX DUF4988 PF16378.5 GBG92647.1 - 1.1 8.8 5.7 12 5.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function bZIP_2 PF07716.15 GBG92647.1 - 1.5 8.9 17.3 3.9 7.6 1.2 4.2 3 0 0 3 3 3 0 Basic region leucine zipper FlaC_arch PF05377.11 GBG92647.1 - 1.6 9.2 8.0 35 4.9 0.1 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 GBG92647.1 - 4.2 7.7 9.9 7.5 6.9 0.4 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF5069 PF16798.5 GBG92648.1 - 0.00031 20.9 0.4 0.19 11.9 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5069) DUF1664 PF07889.12 GBG92648.1 - 0.0098 15.9 2.1 0.0098 15.9 2.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) APOBEC_C PF05240.14 GBG92648.1 - 0.038 13.9 0.2 0.13 12.2 0.2 2.0 1 0 0 1 1 1 0 APOBEC-like C-terminal domain NRDE-2 PF08424.10 GBG92648.1 - 0.11 11.7 2.1 0.17 10.9 2.1 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference ThiS PF02597.20 GBG92648.1 - 0.6 10.8 2.2 1.7 9.4 0.8 2.2 2 0 0 2 2 2 0 ThiS family PEP-utilisers_N PF05524.13 GBG92648.1 - 0.9 9.7 5.0 1.4 9.2 3.7 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal HrpJ PF07201.11 GBG92648.1 - 2 8.7 8.7 0.97 9.7 5.8 1.9 2 0 0 2 2 2 0 HrpJ-like domain Myb_DNA-bind_4 PF13837.6 GBG92649.1 - 0.02 15.2 2.1 0.28 11.6 0.6 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 GBG92650.1 - 3.6e-23 82.0 0.0 7.5e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92650.1 - 4.1e-15 55.9 0.0 6.6e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein NIR_SIR_ferr PF03460.17 GBG92650.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain RT_RNaseH_2 PF17919.1 GBG92652.1 - 5.3e-25 87.4 0.0 2.1e-24 85.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92652.1 - 2.4e-21 76.0 0.0 8e-21 74.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92652.1 - 8.6e-10 38.5 0.9 6e-09 35.7 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG92652.1 - 5.8e-06 26.9 0.0 1.4e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG92652.1 - 1.7e-05 25.0 0.0 9.2e-05 22.6 0.0 2.3 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG92652.1 - 2.7e-05 24.6 0.0 8.9e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 GBG92652.1 - 0.0033 17.3 0.1 0.009 15.9 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG92652.1 - 0.0036 17.1 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG92652.1 - 0.015 15.6 4.0 0.16 12.3 0.0 4.0 3 0 0 3 3 3 0 Retrotransposon gag protein Asp_protease PF09668.10 GBG92652.1 - 0.046 13.5 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease FA_desaturase PF00487.24 GBG92654.1 - 5.1e-35 121.5 24.9 8e-35 120.9 24.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase gag-asp_proteas PF13975.6 GBG92655.1 - 6.5e-06 26.6 0.1 0.00012 22.6 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92655.1 - 0.00021 21.8 0.0 0.00076 20.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 GBG92655.1 - 0.13 12.4 0.7 0.3 11.2 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Hexapep PF00132.24 GBG92656.1 - 0.015 15.0 0.4 0.083 12.7 0.3 2.3 1 1 1 2 2 2 0 Bacterial transferase hexapeptide (six repeats) HSP20 PF00011.21 GBG92657.1 - 6.4e-27 93.7 0.1 1.3e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG92657.1 - 8e-08 31.7 0.0 1.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Glyco_transf_64 PF09258.10 GBG92658.1 - 1.3e-42 145.7 0.0 2.1e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 GBG92658.1 - 8e-07 28.9 0.3 0.0011 18.6 0.3 3.3 2 1 0 2 2 2 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 GBG92658.1 - 0.0074 16.3 0.2 0.016 15.2 0.2 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CdiI_N PF18228.1 GBG92658.1 - 0.02 14.7 0.1 6 6.8 0.0 2.5 2 0 0 2 2 2 0 CdiI N-terminal domain Mannosyl_trans3 PF11051.8 GBG92658.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative zf-CCHC PF00098.23 GBG92659.1 - 5.3e-06 26.3 2.6 9.7e-06 25.4 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92659.1 - 0.038 13.8 4.0 0.047 13.5 1.1 2.2 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 GBG92660.1 - 1.3e-24 87.0 0.1 2.6e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG92660.1 - 3.7e-07 30.6 0.3 1.6e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92660.1 - 1.8e-06 28.5 0.0 6.7e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG92660.1 - 4.8e-05 23.2 0.0 9.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92660.1 - 5e-05 23.1 0.0 9.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease ZapB PF06005.12 GBG92660.1 - 0.029 14.8 0.2 0.029 14.8 0.2 3.4 3 0 0 3 3 3 0 Cell division protein ZapB Retrotrans_gag PF03732.17 GBG92660.1 - 0.4 11.0 5.8 0.14 12.5 1.4 2.6 2 1 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 GBG92662.1 - 2.5e-14 53.3 0.1 4.1e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG92662.1 - 2.1e-06 28.2 0.0 3.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG92662.1 - 1e-05 25.3 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92662.1 - 8e-05 23.2 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92662.1 - 0.00071 19.4 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease HIP1_clath_bdg PF16515.5 GBG92663.1 - 0.0028 18.2 3.4 0.0028 18.2 3.4 3.6 4 1 0 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Retrotrans_gag PF03732.17 GBG92663.1 - 0.017 15.4 0.1 0.017 15.4 0.1 2.8 2 1 0 2 2 2 0 Retrotransposon gag protein DUF4781 PF16013.5 GBG92663.1 - 0.047 12.5 1.9 0.085 11.6 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Oleosin PF01277.17 GBG92664.1 - 7.1e-05 22.5 9.4 0.00014 21.6 9.4 1.5 1 1 0 1 1 1 1 Oleosin TIM PF00121.18 GBG92665.1 - 1.8e-86 289.5 0.2 2.8e-86 288.9 0.2 1.3 1 0 0 1 1 1 1 Triosephosphate isomerase DUF659 PF04937.15 GBG92665.1 - 2.1e-19 69.9 0.0 4.8e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG92665.1 - 2.7e-17 62.6 0.0 5.8e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92665.1 - 4.1e-07 29.7 0.0 7.9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92665.1 - 2.1e-05 24.7 0.0 5.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG92665.1 - 7.5 4.6 9.1 11 4.0 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG92665.1 - 8.5 4.5 5.7 13 3.9 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Oleosin PF01277.17 GBG92667.1 - 3e-05 23.7 6.0 7.4e-05 22.5 6.0 1.7 1 1 0 1 1 1 1 Oleosin Oleosin PF01277.17 GBG92668.1 - 0.00014 21.6 8.2 0.00038 20.2 8.2 1.8 1 1 0 1 1 1 1 Oleosin DUF659 PF04937.15 GBG92669.1 - 4.2e-18 65.7 0.0 7.5e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-RVT PF13966.6 GBG92669.1 - 0.0047 17.6 1.5 0.036 14.8 0.2 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Oleosin PF01277.17 GBG92670.1 - 3.4e-05 23.6 10.1 0.00011 22.0 10.1 1.8 1 1 0 1 1 1 1 Oleosin DUF4381 PF14316.6 GBG92670.1 - 0.35 11.1 0.0 0.35 11.1 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) gag-asp_proteas PF13975.6 GBG92671.1 - 3.5e-07 30.7 0.2 4.1e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92671.1 - 0.00055 20.5 0.0 0.0019 18.8 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92671.1 - 0.0083 15.9 0.4 0.015 15.1 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG92671.1 - 0.012 15.9 0.0 0.054 13.8 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease MPM1 PF17234.2 GBG92676.1 - 3.7 7.8 13.7 0.45 10.8 3.0 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 TENA_THI-4 PF03070.16 GBG92678.1 - 6.1e-09 36.0 0.2 0.00017 21.5 0.1 2.6 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Retrotrans_gag PF03732.17 GBG92678.1 - 0.75 10.1 7.3 1.6 9.1 0.5 3.5 3 0 0 3 3 3 0 Retrotransposon gag protein Angiomotin_C PF12240.8 GBG92679.1 - 0.044 13.3 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 Angiomotin C terminal DUF5005 PF16396.5 GBG92681.1 - 0.26 9.9 0.0 0.36 9.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) DUF4187 PF13821.6 GBG92683.1 - 0.00048 19.9 0.5 0.0011 18.6 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG92683.1 - 0.0058 16.9 0.1 0.0058 16.9 0.1 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein GerPC PF10737.9 GBG92683.1 - 0.037 14.1 0.2 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Spore germination protein GerPC DUF3280 PF11684.8 GBG92683.1 - 4.5 7.7 7.4 0.2 12.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2380) RVT_1 PF00078.27 GBG92684.1 - 1.7e-25 89.9 0.1 2.4e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG92684.1 - 2.6e-07 31.2 0.0 5.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92684.1 - 7.5e-07 29.6 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG92684.1 - 1.5e-05 24.7 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG92684.1 - 8.3e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease CCDC53 PF10152.9 GBG92686.1 - 0.04 14.4 1.0 0.063 13.7 1.0 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PAN_4 PF14295.6 GBG92687.1 - 0.0027 17.6 2.7 0.0027 17.6 2.7 1.6 2 0 0 2 2 2 1 PAN domain Nucleotid_trans PF03407.16 GBG92688.1 - 2e-28 99.8 0.0 3.3e-27 95.8 0.0 2.3 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 GBG92689.1 - 2.4e-34 119.2 0.0 4.3e-32 111.8 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 GBG92690.1 - 1.4e-35 123.2 0.0 3.2e-33 115.5 0.0 2.4 3 0 0 3 3 2 1 Nucleotide-diphospho-sugar transferase Nop14 PF04147.12 GBG92690.1 - 8e-06 24.4 12.4 1.1e-05 24.0 12.4 1.0 1 0 0 1 1 1 1 Nop14-like family RR_TM4-6 PF06459.12 GBG92690.1 - 0.0055 16.6 19.2 0.0085 15.9 19.2 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 PTPRCAP PF15713.5 GBG92690.1 - 0.01 16.1 24.7 0.018 15.3 24.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GBG92690.1 - 0.024 13.0 26.8 0.037 12.3 26.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 GBG92690.1 - 0.042 14.0 24.8 0.069 13.3 24.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Sporozoite_P67 PF05642.11 GBG92690.1 - 0.058 11.5 3.0 0.076 11.1 3.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4637 PF15470.6 GBG92690.1 - 0.069 12.9 19.1 0.12 12.1 19.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4746 PF15928.5 GBG92690.1 - 0.082 12.3 15.8 0.14 11.5 15.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Vfa1 PF08432.10 GBG92690.1 - 0.088 13.1 12.8 0.14 12.5 12.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SpoIIP PF07454.11 GBG92690.1 - 0.13 11.7 8.5 0.24 10.8 8.5 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RNA_pol_3_Rpc31 PF11705.8 GBG92690.1 - 0.15 12.3 22.0 0.3 11.3 22.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 GBG92690.1 - 0.25 10.7 27.9 0.36 10.2 27.9 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 GBG92690.1 - 0.25 11.8 7.5 0.5 10.8 7.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Neur_chan_memb PF02932.16 GBG92690.1 - 0.32 11.0 3.6 0.53 10.3 3.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.12 GBG92690.1 - 0.41 9.6 5.6 0.6 9.0 5.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) eIF-3c_N PF05470.12 GBG92690.1 - 0.41 8.9 11.5 0.56 8.4 11.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pox_Ag35 PF03286.14 GBG92690.1 - 0.42 10.4 14.7 0.72 9.6 14.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein LAP1C PF05609.12 GBG92690.1 - 0.43 9.6 7.0 0.59 9.2 7.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DDHD PF02862.17 GBG92690.1 - 0.48 10.5 3.6 0.74 9.9 3.6 1.2 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.7 GBG92690.1 - 0.59 8.2 8.9 0.79 7.8 8.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mpp10 PF04006.12 GBG92690.1 - 0.76 8.2 28.6 1.1 7.6 28.6 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop53 PF07767.11 GBG92690.1 - 0.93 8.8 39.5 1.3 8.3 39.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Drc1-Sld2 PF11719.8 GBG92690.1 - 1.4 8.3 20.2 2 7.8 20.2 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein IFT57 PF10498.9 GBG92690.1 - 1.7 7.6 18.3 2.3 7.1 18.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Presenilin PF01080.17 GBG92690.1 - 1.8 7.2 13.8 2.7 6.7 13.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4614 PF15391.6 GBG92690.1 - 2.3 8.2 11.0 3.7 7.5 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1676 PF07898.13 GBG92690.1 - 2.6 8.0 7.3 5.9 6.9 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) AAA_11 PF13086.6 GBG92690.1 - 2.9 7.6 15.0 4.5 7.0 15.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2151 PF10221.9 GBG92690.1 - 3.4 6.1 9.0 4.6 5.7 9.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Merozoite_SPAM PF07133.11 GBG92690.1 - 3.8 7.5 41.4 5.7 6.9 41.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SLC12 PF03522.15 GBG92690.1 - 4.1 6.3 7.7 6.4 5.7 7.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PI3K_1B_p101 PF10486.9 GBG92690.1 - 4.6 4.9 10.2 6.5 4.4 10.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CLN3 PF02487.17 GBG92690.1 - 6.4 5.7 5.3 9.4 5.2 5.3 1.2 1 0 0 1 1 1 0 CLN3 protein RPN2_C PF18004.1 GBG92690.1 - 6.7 6.6 20.3 13 5.7 20.3 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM60A PF15396.6 GBG92690.1 - 7.4 6.5 9.7 12 5.9 9.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Rrn6 PF10214.9 GBG92690.1 - 7.9 4.8 14.0 11 4.3 14.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DNA_pol_phi PF04931.13 GBG92690.1 - 9 4.3 31.0 13 3.8 31.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3381 PF11861.8 GBG92690.1 - 9.7 6.0 38.3 15 5.3 38.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RPA43_OB PF17875.1 GBG92690.1 - 9.8 6.8 9.6 19 5.9 9.6 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RT_RNaseH PF17917.1 GBG92692.1 - 6.4e-20 71.4 0.0 1.2e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92692.1 - 2.6e-18 65.9 0.3 7.3e-18 64.4 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG92692.1 - 4.9e-15 55.4 0.0 9.6e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92692.1 - 8.1e-06 26.0 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG92692.1 - 0.0026 17.7 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG92692.1 - 0.0028 17.9 0.1 0.0059 16.8 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger pKID PF02173.17 GBG92692.1 - 0.15 11.6 0.2 5.6 6.5 0.1 2.7 2 0 0 2 2 2 0 pKID domain DUF2052 PF09747.9 GBG92693.1 - 8.1 6.5 25.0 9.5 6.3 25.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDE_1 PF03184.19 GBG92695.1 - 5.1e-09 36.0 0.1 7.3e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF659 PF04937.15 GBG92696.1 - 5.2e-18 65.4 0.0 9.1e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DDE_Tnp_4 PF13359.6 GBG92698.1 - 3.8e-31 107.9 0.0 1.5e-30 106.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92698.1 - 7.9e-15 55.0 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92698.1 - 0.00026 20.7 0.4 2.1 7.9 0.0 3.2 3 0 0 3 3 3 2 Transposase DDE domain RT_RNaseH_2 PF17919.1 GBG92701.1 - 8.6e-20 70.6 0.0 1.7e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92701.1 - 4.3e-16 59.1 0.0 9.3e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92701.1 - 4.7e-10 39.4 0.0 7.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5387 PF17361.2 GBG92701.1 - 0.25 11.0 0.4 0.46 10.1 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5387) rve PF00665.26 GBG92702.1 - 3.1e-12 46.7 0.0 9.4e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain MAGE_N PF12440.8 GBG92702.1 - 2.1 9.1 5.9 93 3.8 4.8 2.5 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Rhodanese PF00581.20 GBG92703.1 - 3.8e-16 59.5 0.0 6.3e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain DDE_Tnp_4 PF13359.6 GBG92704.1 - 3.2e-23 82.2 0.0 5.7e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92704.1 - 2.7e-10 40.2 0.0 4.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein KH_7 PF17214.3 GBG92704.1 - 0.025 14.5 0.3 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 KH domain Myb_DNA-bind_4 PF13837.6 GBG92705.1 - 2.2e-06 27.9 3.8 8.2e-06 26.1 1.1 2.7 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG92706.1 - 1.5e-26 92.3 0.0 2.8e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92706.1 - 1.7e-22 79.7 0.0 3.3e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92706.1 - 8.1e-10 38.6 0.1 1.5e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG92706.1 - 0.0018 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG92706.1 - 0.0028 17.7 1.6 0.0028 17.7 1.6 2.1 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.6 GBG92706.1 - 0.013 16.0 0.1 0.029 14.9 0.1 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92706.1 - 0.078 13.6 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 GBG92706.1 - 0.09 12.6 1.9 0.19 11.6 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 GBG92706.1 - 0.16 11.8 0.2 0.29 10.9 0.2 1.4 1 0 0 1 1 1 0 Aspartyl protease CDC45 PF02724.14 GBG92706.1 - 0.42 8.9 35.4 0.15 10.3 9.0 2.2 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 GBG92706.1 - 0.72 8.0 49.5 0.35 9.0 18.8 2.2 2 0 0 2 2 2 0 Nop14-like family Zip PF02535.22 GBG92707.1 - 1.2e-40 139.7 54.3 2.2e-36 125.7 37.7 4.2 2 1 0 2 2 2 2 ZIP Zinc transporter TMEM132D_C PF15706.5 GBG92707.1 - 0.0034 17.1 0.1 1.3 8.8 0.0 3.8 3 0 0 3 3 3 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term RVT_1 PF00078.27 GBG92708.1 - 1.1e-14 54.5 0.1 1.6e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCDC106 PF15794.5 GBG92708.1 - 0.019 14.7 2.7 0.033 13.9 2.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 GBG92708.1 - 0.21 9.8 7.9 0.29 9.4 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Dynamin_M PF01031.20 GBG92710.1 - 1.3e-101 339.6 0.0 2.2e-101 338.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 GBG92710.1 - 1.7e-54 184.4 0.0 2.8e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GBG92710.1 - 2.8e-10 40.2 0.6 9.2e-10 38.6 0.6 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GBG92710.1 - 1.4e-05 25.1 0.1 8.7e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GBG92710.1 - 0.086 12.4 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Integrase_H2C2 PF17921.1 GBG92711.1 - 7.9e-14 51.5 0.1 2e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92711.1 - 2e-06 28.0 0.0 6.4e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GBG92711.1 - 0.00012 22.2 0.0 0.00035 20.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 GBG92711.1 - 0.00028 21.4 0.5 0.00095 19.7 0.0 2.2 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92711.1 - 0.0016 19.0 0.0 0.0054 17.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease PTPRCAP PF15713.5 GBG92711.1 - 0.075 13.3 7.2 0.37 11.1 7.2 2.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 GBG92711.1 - 5.2 6.7 6.3 14 5.4 6.3 1.7 1 0 0 1 1 1 0 FAM176 family Myb_DNA-bind_4 PF13837.6 GBG92712.1 - 4.2e-11 43.1 2.7 4.5e-11 43.0 0.4 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG92712.1 - 0.0078 16.5 1.0 0.025 14.9 0.2 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4187 PF13821.6 GBG92713.1 - 0.001 18.8 1.2 0.0034 17.1 1.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG92713.1 - 0.0028 17.9 0.2 0.0028 17.9 0.2 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein Lipin_mid PF16876.5 GBG92713.1 - 0.039 14.1 0.3 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF3947 PF13135.6 GBG92713.1 - 0.05 13.8 3.5 2.6 8.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) CHASE3 PF05227.13 GBG92714.1 - 0.13 12.2 0.2 0.3 11.0 0.1 1.6 1 1 1 2 2 2 0 CHASE3 domain Integrase_H2C2 PF17921.1 GBG92716.1 - 1.3e-19 70.1 0.3 2.4e-19 69.2 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92716.1 - 3.6e-15 56.2 0.0 9e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG92716.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 GBG92717.1 - 1.3e-08 35.3 0.0 3.4e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92717.1 - 1.1e-07 32.3 0.0 4.5e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG92717.1 - 3.4e-06 26.9 0.0 8.5e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG92717.1 - 0.0032 17.3 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Aldo_ket_red PF00248.21 GBG92719.1 - 5.4e-61 206.4 0.0 6.1e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HSP70 PF00012.20 GBG92720.1 - 3.3e-52 177.5 11.8 5e-44 150.5 0.1 4.0 2 1 2 4 4 4 4 Hsp70 protein FGGY_C PF02782.16 GBG92720.1 - 0.0023 17.7 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 GBG92720.1 - 0.011 15.0 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase zf-CCHC PF00098.23 GBG92720.1 - 0.016 15.2 1.8 0.033 14.3 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle TIM PF00121.18 GBG92721.1 - 2.3e-23 82.8 0.0 1.1e-07 31.4 0.0 4.0 3 1 0 3 3 3 3 Triosephosphate isomerase HSP70 PF00012.20 GBG92721.1 - 1.1e-21 76.7 0.0 1.7e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein FliG_C PF01706.16 GBG92721.1 - 0.015 15.5 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 FliG C-terminal domain DUF3775 PF12616.8 GBG92721.1 - 0.052 13.6 0.3 4.7 7.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3775) Ribosomal_L37 PF08561.10 GBG92721.1 - 1.9 9.0 4.8 20 5.8 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 HSP70 PF00012.20 GBG92722.1 - 5.6e-22 77.7 0.0 8.9e-22 77.0 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein NAC PF01849.18 GBG92722.1 - 6.5e-05 22.8 0.1 0.00013 21.8 0.1 1.5 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 GBG92722.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF1943 PF09172.11 GBG92723.1 - 1.3 8.2 7.1 1.8 7.7 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) V_ATPase_I PF01496.19 GBG92723.1 - 1.6 6.6 7.9 1.7 6.5 7.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIF_alpha PF05793.12 GBG92723.1 - 2.2 6.8 26.4 6 5.3 26.3 1.5 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ALMT PF11744.8 GBG92723.1 - 2.3 7.0 8.5 3.1 6.5 8.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter RRN3 PF05327.11 GBG92723.1 - 7.3 5.0 9.6 10 4.5 9.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Retrotrans_gag PF03732.17 GBG92725.1 - 0.0021 18.3 4.8 0.0039 17.4 0.0 3.3 4 0 0 4 4 4 1 Retrotransposon gag protein DivIC PF04977.15 GBG92725.1 - 0.3 10.9 0.0 0.3 10.9 0.0 2.7 3 0 0 3 3 3 0 Septum formation initiator ADIP PF11559.8 GBG92725.1 - 2.3 8.3 12.6 0.3 11.2 0.8 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding RVT_1 PF00078.27 GBG92726.1 - 2e-25 89.6 0.1 3.6e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG92726.1 - 5.8e-18 64.8 0.2 1.2e-17 63.8 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 GBG92726.1 - 9.1e-13 48.4 0.0 2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG92726.1 - 9.2e-10 38.4 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92726.1 - 2.7e-08 34.4 0.0 8.1e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG92726.1 - 1e-06 28.7 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92726.1 - 5e-06 26.7 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG92726.1 - 1.5e-05 25.4 0.0 5.4e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease 4HBT_3 PF13622.6 GBG92726.1 - 0.0023 18.2 0.1 0.17 12.2 0.1 2.5 2 0 0 2 2 2 1 Thioesterase-like superfamily Retrotrans_gag PF03732.17 GBG92726.1 - 0.0028 17.9 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG92726.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Es2 PF09751.9 GBG92727.1 - 0.93 9.2 14.9 1.2 8.8 14.9 1.1 1 0 0 1 1 1 0 Nuclear protein Es2 Exonuc_VII_L PF02601.15 GBG92727.1 - 5.6 6.4 9.7 8.7 5.8 9.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Crystall_3 PF08964.10 GBG92730.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin zf-CCHC PF00098.23 GBG92731.1 - 0.045 13.8 1.9 0.071 13.2 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 GBG92731.1 - 0.046 14.3 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92731.1 - 0.089 13.4 0.3 0.4 11.3 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease MatE PF01554.18 GBG92734.1 - 3.1e-55 186.2 28.7 4.6e-34 117.4 8.8 2.4 2 0 0 2 2 2 2 MatE DUF3262 PF11660.8 GBG92734.1 - 0.0098 16.3 0.3 0.058 13.8 0.3 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3262) VirB3 PF05101.13 GBG92734.1 - 0.038 14.2 1.2 0.038 14.2 1.2 3.1 3 1 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein Myb_DNA-bind_4 PF13837.6 GBG92735.1 - 1.5e-09 38.1 2.4 1.1e-07 32.1 0.9 2.4 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG92735.1 - 0.052 13.9 0.5 0.18 12.1 0.1 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG92735.1 - 0.12 12.5 2.3 0.14 12.2 0.6 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain YopD PF05844.12 GBG92736.1 - 0.16 10.9 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 YopD protein DUF659 PF04937.15 GBG92738.1 - 8.5e-23 80.9 0.0 1.5e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG92739.1 - 1.6e-25 89.1 0.0 3.1e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92739.1 - 2.2e-22 79.3 0.0 4.8e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92739.1 - 1.9e-18 66.8 0.4 3.5e-17 62.7 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG92739.1 - 8.1e-07 29.5 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92739.1 - 0.00015 22.3 0.0 0.00042 20.9 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease BUD22 PF09073.10 GBG92739.1 - 0.21 10.9 18.7 0.88 8.8 0.6 2.3 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 GBG92739.1 - 0.26 10.7 10.3 0.44 9.9 10.3 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG92739.1 - 0.52 8.5 13.7 0.84 7.8 13.7 1.2 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 GBG92739.1 - 1.2 7.4 6.6 1.9 6.7 6.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pox_Ag35 PF03286.14 GBG92739.1 - 2.1 8.1 5.5 5.4 6.8 5.5 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 GBG92739.1 - 3.2 5.9 9.3 4.9 5.3 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG92742.1 - 1.3e-34 119.6 0.0 2.4e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG92742.1 - 2.9e-06 27.1 0.0 6.7e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92742.1 - 4.2e-06 27.3 0.0 9.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92742.1 - 0.00035 21.1 0.0 0.0012 19.4 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92742.1 - 0.037 13.8 0.0 3.7 7.4 0.0 2.6 2 1 0 2 2 2 0 Aspartyl protease DUF659 PF04937.15 GBG92743.1 - 1.4e-07 31.5 0.1 2.6e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92743.1 - 0.012 15.4 0.1 0.038 13.8 0.1 1.9 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region CPBP PF02517.16 GBG92745.1 - 0.0029 17.9 0.0 0.004 17.5 0.0 1.2 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease Rdx PF10262.9 GBG92745.1 - 0.13 12.5 0.2 0.19 12.0 0.2 1.3 1 1 0 1 1 1 0 Rdx family CDC45 PF02724.14 GBG92746.1 - 1.1 7.5 7.6 1.6 7.0 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein LRS4 PF10422.9 GBG92746.1 - 6.5 6.2 6.9 17 4.9 0.4 2.2 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 CDC27 PF09507.10 GBG92746.1 - 8.9 5.6 12.0 0.12 11.8 4.2 1.7 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 RVT_1 PF00078.27 GBG92747.1 - 0.085 12.4 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Shugoshin_N PF07558.11 GBG92748.1 - 0.013 15.3 2.1 2.9 7.8 0.1 2.7 3 0 0 3 3 2 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 GBG92748.1 - 0.019 15.2 12.2 0.044 14.0 12.2 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BST2 PF16716.5 GBG92748.1 - 0.14 12.8 6.5 0.32 11.6 6.5 1.6 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 HSP70 PF00012.20 GBG92748.1 - 0.16 10.1 4.6 0.24 9.6 4.6 1.2 1 0 0 1 1 1 0 Hsp70 protein Spc7 PF08317.11 GBG92748.1 - 0.23 10.3 9.7 0.38 9.6 9.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 GBG92748.1 - 0.76 10.3 12.8 6.5 7.3 5.7 2.8 1 1 2 3 3 3 0 Cell division protein ZapB Atg14 PF10186.9 GBG92748.1 - 1.8 7.6 7.7 2.7 7.0 7.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC106 PF15794.5 GBG92748.1 - 1.8 8.2 11.1 5.6 6.6 11.1 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 Cep57_MT_bd PF06657.13 GBG92748.1 - 2 8.9 11.0 0.75 10.3 3.7 2.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CLZ PF16526.5 GBG92748.1 - 2.4 8.6 7.3 3.5 8.0 1.9 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 GBG92748.1 - 3.7 7.7 10.9 2.6 8.2 0.9 3.0 2 1 1 3 3 3 0 bZIP transcription factor V_ATPase_I PF01496.19 GBG92748.1 - 9.3 4.0 6.1 13 3.5 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DAO PF01266.24 GBG92749.1 - 4.3e-38 131.8 0.1 7e-38 131.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 GBG92749.1 - 6.6e-31 106.8 0.0 2e-30 105.2 0.0 1.8 1 1 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 GBG92749.1 - 7.8e-07 28.8 0.4 1.3e-06 28.0 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG92749.1 - 3.9e-05 22.9 2.5 4.1e-05 22.8 1.5 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GBG92749.1 - 0.00019 20.8 0.5 0.00051 19.4 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GBG92749.1 - 0.0002 20.6 0.6 0.0056 15.8 0.8 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 GBG92749.1 - 0.0054 15.5 0.6 0.0079 14.9 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 GBG92749.1 - 0.016 15.8 0.8 0.048 14.2 0.8 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GBG92749.1 - 0.033 14.1 0.5 0.081 12.8 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 GBG92749.1 - 0.12 12.7 1.9 0.64 10.3 1.4 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GBG92749.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RVT_1 PF00078.27 GBG92750.1 - 8e-30 104.0 0.1 1.4e-29 103.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG92750.1 - 5.4e-15 55.6 0.0 1.1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG92750.1 - 7.7e-14 51.5 0.0 1.9e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92750.1 - 5.7e-05 23.4 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG92750.1 - 9.5e-05 22.2 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG92750.1 - 0.00029 21.3 0.0 0.00089 19.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92750.1 - 0.012 16.2 0.0 0.035 14.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG92750.1 - 0.028 14.2 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Zip PF02535.22 GBG92750.1 - 0.28 10.4 7.0 0.52 9.5 7.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.17 GBG92750.1 - 0.29 11.3 5.2 0.18 11.9 0.6 2.4 2 0 0 2 2 2 0 DDHD domain RNA_pol_Rpc4 PF05132.14 GBG92750.1 - 0.76 10.2 12.6 0.2 12.1 6.2 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 SRP-alpha_N PF04086.13 GBG92750.1 - 1.4 8.7 14.4 0.014 15.3 3.0 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF4366 PF14283.6 GBG92750.1 - 5.3 7.1 6.0 1.8 8.6 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) RT_RNaseH PF17917.1 GBG92753.1 - 1.2e-19 70.5 0.0 2.2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92753.1 - 1.6e-12 47.3 0.0 2.8e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 GBG92753.1 - 0.06 11.6 6.7 0.073 11.3 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG92753.1 - 0.99 8.8 9.2 1.4 8.3 9.2 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG92753.1 - 2.7 6.2 8.1 3.5 5.8 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Drc1-Sld2 PF11719.8 GBG92754.1 - 8.8 5.7 17.4 12 5.4 17.4 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein N6_N4_Mtase PF01555.18 GBG92755.1 - 3.6e-09 36.7 0.0 1.5e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 DNA methylase Cons_hypoth95 PF03602.15 GBG92755.1 - 0.025 14.2 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 BUD22 PF09073.10 GBG92759.1 - 0.16 11.3 40.0 0.23 10.7 40.0 1.3 1 0 0 1 1 1 0 BUD22 YABBY PF04690.13 GBG92759.1 - 1.7 9.2 4.0 3.3 8.2 4.0 1.6 1 1 0 1 1 1 0 YABBY protein SDA1 PF05285.12 GBG92759.1 - 6.7 6.0 55.4 9.5 5.5 55.4 1.3 1 0 0 1 1 1 0 SDA1 rve PF00665.26 GBG92760.1 - 1.4e-15 57.5 0.0 3.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG92760.1 - 5.9e-15 55.1 0.2 1.4e-14 53.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG92760.1 - 0.0025 18.0 0.3 0.006 16.8 0.3 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 GBG92760.1 - 0.028 14.2 0.0 0.11 12.3 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 GBG92761.1 - 3.1e-26 92.3 0.0 4.2e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92761.1 - 3e-06 27.2 0.0 1.3e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG92761.1 - 0.053 12.6 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF3138 PF11336.8 GBG92762.1 - 0.58 8.7 1.0 0.92 8.0 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Poty_PP PF08440.10 GBG92763.1 - 0.029 13.5 0.7 0.057 12.5 0.7 1.4 1 0 0 1 1 1 0 Potyviridae polyprotein eRF1_3 PF03465.15 GBG92766.1 - 0.024 15.1 1.0 0.18 12.3 0.2 2.0 2 0 0 2 2 2 0 eRF1 domain 3 PWI PF01480.17 GBG92767.1 - 9.8e-06 25.8 0.0 1.6e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 GBG92767.1 - 0.016 15.1 0.9 0.016 15.1 0.9 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RXLR PF16810.5 GBG92768.1 - 0.097 13.1 9.6 0.26 11.7 9.6 1.6 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity FtsJ PF01728.19 GBG92770.1 - 3.3e-66 222.7 0.0 4.1e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Asp_protease_2 PF13650.6 GBG92771.1 - 0.068 13.8 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Dimer_Tnp_hAT PF05699.14 GBG92772.1 - 7.3e-13 48.1 1.3 1e-11 44.4 1.3 2.6 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region DBD_Tnp_Hermes PF10683.9 GBG92772.1 - 1.2e-06 28.1 0.2 2.8e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 Hermes transposase DNA-binding domain Tet_JBP PF12851.7 GBG92772.1 - 0.17 11.2 0.7 1.3 8.3 0.7 2.0 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DUF659 PF04937.15 GBG92773.1 - 4.9e-33 114.1 2.4 1.2e-32 112.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DDE_Tnp_4 PF13359.6 GBG92773.1 - 1.3e-11 44.4 0.0 2.4e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.14 GBG92773.1 - 0.00042 20.0 1.7 0.0012 18.6 1.7 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_Tnp_1 PF01609.21 GBG92773.1 - 0.085 12.5 0.6 0.57 9.8 0.0 2.5 3 0 0 3 3 3 0 Transposase DDE domain Augurin PF15187.6 GBG92773.1 - 0.12 12.6 0.3 0.47 10.6 0.3 2.0 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 Myb_DNA-bind_4 PF13837.6 GBG92774.1 - 0.017 15.5 0.9 0.032 14.6 0.5 1.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain HisKA PF00512.25 GBG92775.1 - 7.5e-15 54.7 0.0 1.5e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Aft1_HRR PF11787.8 GBG92775.1 - 0.1 13.8 0.5 0.49 11.6 0.1 2.2 2 0 0 2 2 2 0 Aft1 HRR domain zf-RVT PF13966.6 GBG92776.1 - 2.1e-11 44.4 0.5 6.1e-11 42.9 0.5 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase ParD_like PF11903.8 GBG92776.1 - 0.015 15.3 0.1 0.24 11.5 0.0 2.4 2 0 0 2 2 2 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system Ank_4 PF13637.6 GBG92776.1 - 0.056 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Thioredoxin PF00085.20 GBG92777.1 - 3.4e-17 62.3 0.0 5.9e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin ERp29 PF07749.12 GBG92777.1 - 1.2e-14 55.0 0.1 1.9e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 GBG92777.1 - 1.1e-05 24.9 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GBG92777.1 - 0.031 14.7 1.1 0.15 12.5 0.1 2.6 3 1 0 3 3 3 0 Thioredoxin-like domain DUF4558 PF15104.6 GBG92778.1 - 4.3e-07 29.9 2.2 9.6e-07 28.8 2.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4558) Phage_term_sma PF07141.11 GBG92778.1 - 0.017 14.9 0.0 0.023 14.5 0.0 1.3 1 1 0 1 1 1 0 Putative bacteriophage terminase small subunit AIF-MLS PF14962.6 GBG92780.1 - 0.48 10.4 6.2 0.9 9.5 6.2 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence RT_RNaseH_2 PF17919.1 GBG92781.1 - 9.2e-33 112.3 0.0 1.8e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92781.1 - 1.2e-31 110.0 0.1 2.2e-31 109.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92781.1 - 6.6e-29 100.3 0.0 1.4e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92781.1 - 0.0011 19.2 0.2 0.0093 16.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain DUF1604 PF07713.13 GBG92782.1 - 1.7e-33 114.3 3.0 1.7e-33 114.3 3.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 GBG92782.1 - 0.00049 19.9 1.4 0.00049 19.9 1.4 3.5 4 0 0 4 4 4 2 G-patch domain Surp PF01805.20 GBG92782.1 - 0.0005 20.0 0.0 0.00097 19.1 0.0 1.5 1 0 0 1 1 1 1 Surp module RT_RNaseH PF17917.1 GBG92784.1 - 1.1e-22 80.3 0.0 2.9e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92784.1 - 3.3e-22 78.4 0.0 1.7e-21 76.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92784.1 - 1.6e-10 40.9 0.3 1.8e-09 37.5 0.0 2.5 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 GBG92784.1 - 2.8e-08 34.3 0.0 7.3e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92784.1 - 1.2e-07 31.6 0.0 7.2e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG92784.1 - 3.1e-06 27.6 0.0 9.4e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG92784.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease AMP-binding_C_2 PF14535.6 GBG92784.1 - 0.16 12.3 0.0 0.82 10.0 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Topo_Zn_Ribbon PF08272.11 GBG92785.1 - 0.13 12.0 0.2 0.25 11.0 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG92785.1 - 0.43 10.7 1.9 0.66 10.2 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle DDE_Tnp_4 PF13359.6 GBG92788.1 - 1.4e-32 112.6 0.0 1.9e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92788.1 - 1.3e-17 64.1 0.0 2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92788.1 - 0.0039 16.9 0.1 2.1 7.9 0.0 2.3 2 0 0 2 2 2 2 Transposase DDE domain Coilin_N PF15862.5 GBG92790.1 - 6.8 6.5 9.6 14 5.4 9.6 1.5 1 0 0 1 1 1 0 Coilin N-terminus DDE_Tnp_4 PF13359.6 GBG92791.1 - 1.7e-13 50.6 1.0 2.8e-13 49.8 0.0 1.9 3 0 0 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92791.1 - 1.3e-08 34.8 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92791.1 - 0.00077 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Spore_coat_CotO PF14153.6 GBG92792.1 - 0.00087 19.3 2.6 0.0011 18.9 2.6 1.2 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.15 GBG92792.1 - 0.16 10.7 1.2 0.2 10.4 1.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 GBG92792.1 - 0.71 9.0 5.1 1.2 8.3 5.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NB-ARC PF00931.22 GBG92793.1 - 2.5e-30 105.5 0.0 3.8e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain LRR_8 PF13855.6 GBG92793.1 - 1.1e-10 41.1 20.7 2.1e-06 27.4 0.1 8.6 8 1 0 9 9 9 3 Leucine rich repeat LRR_4 PF12799.7 GBG92793.1 - 6.2e-10 39.2 29.4 0.0026 18.1 1.4 12.2 8 3 6 15 15 15 5 Leucine Rich repeats (2 copies) AAA_22 PF13401.6 GBG92793.1 - 0.0016 18.7 0.0 0.0093 16.2 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GBG92793.1 - 0.0029 18.0 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 GBG92793.1 - 0.048 14.2 0.0 0.22 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GBG92793.1 - 0.17 12.0 0.8 0.76 9.9 0.1 2.4 3 0 0 3 3 3 0 AAA domain Cwf_Cwc_15 PF04889.12 GBG92794.1 - 0.0027 17.5 12.5 0.0034 17.2 12.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 GBG92794.1 - 0.78 9.7 10.5 0.84 9.6 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.13 GBG92794.1 - 0.94 8.2 3.3 1.2 7.9 3.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FYDLN_acid PF09538.10 GBG92794.1 - 2.4 8.9 17.4 4.9 7.9 17.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BTB PF00651.31 GBG92795.1 - 4.4e-14 52.7 0.0 1.4e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Porin_3 PF01459.22 GBG92796.1 - 1.6e-45 155.7 0.0 1.8e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin MDM10 PF12519.8 GBG92796.1 - 0.0002 20.4 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 BTB PF00651.31 GBG92797.1 - 1.4e-12 47.8 0.0 3.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 GBG92797.1 - 0.0077 16.3 0.0 0.66 10.1 0.0 2.3 2 0 0 2 2 2 2 SPRY domain DDE_Tnp_4 PF13359.6 GBG92799.1 - 3e-13 49.7 0.0 9.5e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92799.1 - 7.2e-09 35.5 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92799.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain Bd3614-deam PF14439.6 GBG92799.1 - 0.033 14.3 2.2 0.073 13.1 2.2 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase Trypan_PARP PF05887.11 GBG92799.1 - 0.37 10.8 6.0 0.6 10.1 6.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PARP PF00644.20 GBG92800.1 - 4.5e-45 153.6 0.0 5.5e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Anoctamin PF04547.12 GBG92801.1 - 1.5e-89 300.9 16.1 1.9e-89 300.6 16.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 GBG92801.1 - 0.002 17.9 0.0 0.068 12.9 0.0 2.7 2 1 1 3 3 3 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin CitMHS PF03600.16 GBG92801.1 - 0.016 14.4 0.3 0.035 13.3 0.3 1.6 1 1 0 1 1 1 0 Citrate transporter Rhomboid_SP PF12595.8 GBG92802.1 - 0.13 11.6 2.0 0.22 10.8 0.1 2.1 1 1 1 2 2 2 0 Rhomboid serine protease DD_K PF12121.8 GBG92802.1 - 1.4 9.1 7.0 4.2 7.6 7.0 1.8 1 0 0 1 1 1 0 Dermaseptin MFMR_assoc PF16596.5 GBG92803.1 - 6.3 7.3 20.6 0.7 10.4 14.8 2.2 2 0 0 2 2 2 0 Disordered region downstream of MFMR Dimer_Tnp_hAT PF05699.14 GBG92807.1 - 2.2e-06 27.4 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Gp_dh_C PF02800.20 GBG92808.1 - 6e-11 42.2 0.0 9.4e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_C PF02800.20 GBG92809.1 - 2.2e-69 232.0 0.0 3e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG92809.1 - 5.5e-38 129.4 0.0 1.9e-37 127.6 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG92809.1 - 0.0045 17.1 0.1 0.016 15.4 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Radical_SAM PF04055.21 GBG92809.1 - 0.083 13.3 0.0 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 Radical SAM superfamily Gp_dh_C PF02800.20 GBG92811.1 - 5.7e-70 234.0 0.0 7.7e-70 233.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG92811.1 - 5e-38 129.5 0.0 1.9e-37 127.6 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG92811.1 - 0.0041 17.2 0.3 0.016 15.4 0.0 2.2 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Radical_SAM PF04055.21 GBG92811.1 - 0.034 14.5 0.0 0.43 10.9 0.0 2.1 2 0 0 2 2 2 0 Radical SAM superfamily RT_RNaseH_2 PF17919.1 GBG92812.1 - 1.6e-24 85.8 0.0 2.8e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92812.1 - 7.9e-22 77.5 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92812.1 - 2.6e-15 56.2 0.9 9e-15 54.5 0.2 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG92812.1 - 0.015 15.5 0.2 0.031 14.5 0.2 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Mucin-like PF16058.5 GBG92816.1 - 2.6e-18 66.0 1.6 1.2 9.3 0.0 10.3 10 1 1 11 11 11 8 Mucin-like CLIP1_ZNF PF16641.5 GBG92821.1 - 0.025 14.5 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 CLIP1 zinc knuckle zf-RVT PF13966.6 GBG92823.1 - 4.3e-06 27.3 2.0 1.7e-05 25.4 2.0 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92824.1 - 2.6e-20 72.3 0.0 5.6e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92824.1 - 1.7e-16 60.1 0.4 3.3e-16 59.1 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92824.1 - 1.4e-12 47.8 0.0 3.7e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG92824.1 - 3.7e-11 43.2 0.0 8.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG92824.1 - 0.00058 20.1 0.9 0.0032 17.7 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG92824.1 - 0.024 14.8 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG92824.1 - 0.034 13.7 0.4 0.075 12.5 0.1 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG92824.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 U1snRNP70_N PF12220.8 GBG92824.1 - 0.13 12.9 0.9 1.1 10.0 0.1 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Trimer_CC PF08954.11 GBG92825.1 - 1.2 8.7 12.8 0.53 9.9 0.3 4.1 3 1 1 4 4 4 0 Trimerisation motif SpoOE-like PF09388.10 GBG92825.1 - 2.9 7.8 9.7 0.43 10.5 2.1 3.0 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein RVT_1 PF00078.27 GBG92827.1 - 1.1e-33 116.6 0.0 1.6e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG92828.1 - 4.8e-30 104.7 0.0 7.6e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG92831.1 - 0.084 13.0 4.2 0.18 11.9 4.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-C4pol PF14260.6 GBG92831.1 - 1.1 9.8 6.4 0.2 12.1 1.3 2.3 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Allexi_40kDa PF05549.11 GBG92831.1 - 3.1 7.2 8.0 9.6 5.6 0.3 2.1 1 1 2 3 3 3 0 Allexivirus 40kDa protein RPW8 PF05659.11 GBG92833.1 - 0.0034 17.1 8.3 0.0073 16.0 8.3 1.5 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DivIC PF04977.15 GBG92833.1 - 3.5 7.5 6.3 2.1 8.2 0.9 2.7 2 0 0 2 2 2 0 Septum formation initiator DUF5427 PF10310.9 GBG92834.1 - 0.0036 16.3 15.7 0.0044 16.1 15.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) SDA1 PF05285.12 GBG92834.1 - 0.007 15.8 34.2 0.0081 15.6 34.2 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GBG92834.1 - 0.01 14.1 30.4 0.012 13.9 30.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG92834.1 - 0.068 12.5 27.7 0.076 12.4 27.7 1.1 1 0 0 1 1 1 0 BUD22 DUF4045 PF13254.6 GBG92834.1 - 0.27 10.8 14.3 0.32 10.6 14.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FRQ PF09421.10 GBG92834.1 - 0.42 8.6 11.7 0.48 8.4 11.7 1.0 1 0 0 1 1 1 0 Frequency clock protein SpoIIIAH PF12685.7 GBG92834.1 - 0.64 9.8 15.2 0.87 9.4 15.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Vfa1 PF08432.10 GBG92834.1 - 0.92 9.8 16.8 1.3 9.4 16.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_polI_A34 PF08208.11 GBG92834.1 - 1 9.4 22.3 1.4 9.0 22.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SAPS PF04499.15 GBG92834.1 - 1.6 7.4 11.9 1.7 7.4 11.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GBG92834.1 - 1.9 7.2 16.8 2.2 7.0 16.8 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 GBG92834.1 - 2.9 6.8 10.5 3.6 6.5 10.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4407 PF14362.6 GBG92834.1 - 3.6 6.9 6.2 4.1 6.7 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lin-8 PF03353.15 GBG92834.1 - 5.8 6.4 18.8 6.5 6.2 18.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist VIR_N PF15912.5 GBG92834.1 - 6.5 6.3 22.2 12 5.4 22.2 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal LAP1C PF05609.12 GBG92834.1 - 6.9 5.6 16.6 8.1 5.4 16.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 GBG92834.1 - 7 4.7 14.4 8 4.4 14.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4746 PF15928.5 GBG92834.1 - 7.9 5.8 33.6 15 4.9 33.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SLC12 PF03522.15 GBG92834.1 - 8.8 5.2 8.5 10 5.0 8.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 GBG92834.1 - 9.1 5.4 11.5 10 5.2 11.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.6 GBG92834.1 - 9.3 4.9 15.1 11 4.6 15.1 1.1 1 0 0 1 1 1 0 Raftlin Beta_helix PF13229.6 GBG92835.1 - 9.8e-10 38.5 3.3 1.8e-09 37.6 3.3 1.4 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG92835.1 - 0.004 16.5 1.4 0.014 14.7 1.4 1.7 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 GBG92835.1 - 0.028 14.9 1.3 0.028 14.9 1.3 4.8 5 1 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Metal_resist PF13801.6 GBG92835.1 - 0.074 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Heavy-metal resistance DUF5123 PF17161.4 GBG92835.1 - 0.2 12.8 0.9 1.2 10.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) DUF659 PF04937.15 GBG92836.1 - 4.6e-09 36.3 0.0 0.00087 19.2 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92836.1 - 0.0057 16.4 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rap1a PF18602.1 GBG92837.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Rap1a immunity proteins DUF287 PF03384.14 GBG92838.1 - 0.01 16.2 1.3 0.024 15.0 1.3 1.6 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 N6_N4_Mtase PF01555.18 GBG92839.1 - 1e-06 28.6 0.6 2.4e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 DNA methylase SpoIIP PF07454.11 GBG92839.1 - 0.082 12.3 1.8 0.18 11.2 1.8 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NTP_transf_2 PF01909.23 GBG92839.1 - 0.25 11.7 1.0 19 5.6 0.0 3.1 2 1 0 2 2 2 0 Nucleotidyltransferase domain RPA43_OB PF17875.1 GBG92839.1 - 0.71 10.5 6.1 1.9 9.1 6.1 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I SDA1 PF05285.12 GBG92839.1 - 0.92 8.9 19.9 2 7.7 19.9 1.5 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 GBG92839.1 - 3.5 6.7 10.4 6.5 5.9 10.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PRIMA1 PF16101.5 GBG92840.1 - 0.15 12.1 2.0 0.45 10.6 2.0 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CDC45 PF02724.14 GBG92840.1 - 5.1 5.3 11.9 6.8 4.8 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG92841.1 - 6.7e-10 38.8 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92843.1 - 4.5e-27 94.0 0.0 1e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92843.1 - 3.6e-25 88.3 0.0 8.2e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92843.1 - 2.5e-19 69.1 0.5 7.6e-19 67.6 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG92843.1 - 1.8e-09 37.8 0.0 1.2e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG92843.1 - 0.0051 17.0 0.0 0.0051 17.0 0.0 4.1 4 1 0 4 4 4 1 Retrotransposon gag protein Chromo PF00385.24 GBG92843.1 - 0.011 15.6 0.1 0.029 14.3 0.1 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG92843.1 - 0.032 14.4 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG92844.1 - 4.5e-27 94.0 0.0 1e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92844.1 - 3.6e-25 88.3 0.0 8.2e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92844.1 - 2.5e-19 69.1 0.5 7.6e-19 67.6 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG92844.1 - 1.8e-09 37.8 0.0 1.2e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 GBG92844.1 - 0.0051 17.1 0.0 0.0051 17.1 0.0 4.1 4 1 0 4 4 4 1 Retrotransposon gag protein Chromo PF00385.24 GBG92844.1 - 0.011 15.6 0.1 0.029 14.3 0.1 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG92844.1 - 0.032 14.4 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger SPG48 PF14764.6 GBG92845.1 - 3.2e-27 95.4 0.1 5.2e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 AP-5 complex subunit, vesicle trafficking ABC_tran PF00005.27 GBG92846.1 - 1.6e-18 67.6 0.0 5.4e-18 65.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GBG92846.1 - 9.1e-15 55.2 0.5 7.1e-09 35.9 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GBG92846.1 - 0.00049 19.6 0.1 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GBG92846.1 - 0.0033 17.1 0.3 0.0072 16.0 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 GBG92846.1 - 0.012 16.2 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GBG92846.1 - 0.026 14.3 0.9 0.23 11.2 0.5 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GBG92846.1 - 0.027 14.1 0.1 0.058 13.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GBG92846.1 - 0.032 14.6 0.2 0.12 12.7 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GBG92846.1 - 0.063 13.6 1.6 0.1 12.8 0.3 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GBG92846.1 - 0.13 12.1 0.8 0.32 10.9 0.8 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 GBG92846.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 GBG92846.1 - 0.29 9.7 0.7 0.42 9.2 0.7 1.1 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 GBG92847.1 - 2.6e-21 75.2 0.0 4.2e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GBG92847.1 - 0.00067 19.7 0.0 0.002 18.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif OB_RNB PF08206.11 GBG92847.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 GBG92847.1 - 0.22 11.8 0.0 0.34 11.1 0.0 1.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter CDC45 PF02724.14 GBG92848.1 - 1.1 7.5 2.8 1.5 7.0 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DDE_Tnp_4 PF13359.6 GBG92849.1 - 7.2e-31 107.0 0.0 1.3e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92849.1 - 1.2e-14 54.4 0.0 1.9e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92849.1 - 4e-05 23.4 0.8 0.051 13.2 0.0 2.7 3 1 0 3 3 3 2 Transposase DDE domain Glyco_tranf_2_3 PF13641.6 GBG92850.1 - 2.2e-28 99.7 0.0 3.3e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GBG92850.1 - 2e-22 79.8 0.0 3.1e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 GBG92850.1 - 4.1e-21 75.8 4.5 4.1e-21 75.8 4.5 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 GBG92850.1 - 4.5e-16 58.5 8.2 1.2e-08 34.0 1.7 3.1 1 1 2 3 3 3 3 Cellulose synthase Glyco_transf_21 PF13506.6 GBG92850.1 - 1.3e-14 54.0 0.0 2.9e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 GBG92850.1 - 0.027 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_49 PF13896.6 GBG92850.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan IU_nuc_hydro PF01156.19 GBG92851.1 - 9.1e-21 74.7 0.0 1e-20 74.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase O-FucT PF10250.9 GBG92853.1 - 0.0018 18.0 0.0 0.01 15.5 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase K_channel_TID PF07941.11 GBG92853.1 - 0.44 11.0 8.2 0.97 9.9 8.2 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF659 PF04937.15 GBG92855.1 - 3.8e-23 82.0 0.1 7.3e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92855.1 - 6.1e-09 35.6 1.8 0.00028 20.6 0.2 2.6 2 0 0 2 2 2 2 hAT family C-terminal dimerisation region DUF659 PF04937.15 GBG92856.1 - 0.00014 21.8 0.0 0.00038 20.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) APC_N_CC PF16689.5 GBG92856.1 - 0.024 14.7 0.6 0.053 13.6 0.6 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain FlaC_arch PF05377.11 GBG92856.1 - 0.086 13.3 0.3 0.27 11.6 0.3 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Herpes_BLRF2 PF05812.12 GBG92856.1 - 0.3 11.2 2.4 0.6 10.2 2.4 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DDE_Tnp_4 PF13359.6 GBG92857.1 - 3.9e-32 111.1 0.0 6.5e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92857.1 - 1.3e-15 57.6 0.0 2.2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92857.1 - 3.6e-05 23.5 0.7 0.04 13.6 0.1 3.3 3 1 0 3 3 3 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG92857.1 - 0.048 14.0 0.3 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 GBG92858.1 - 4.8e-07 30.1 0.6 2.8e-06 27.6 0.4 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG92858.1 - 0.0013 18.8 0.6 0.0028 17.7 0.6 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF5634_N PF18672.1 GBG92859.1 - 0.069 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5634) RVT_1 PF00078.27 GBG92860.1 - 4.8e-26 91.7 0.0 7.1e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92860.1 - 2.6e-22 78.7 0.0 6e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92860.1 - 9.2e-13 48.4 0.0 1.9e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG92860.1 - 0.022 14.7 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG92860.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Co_AT_N PF12557.8 GBG92861.1 - 0.025 14.5 4.7 0.072 13.0 4.7 1.9 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal gag-asp_proteas PF13975.6 GBG92862.1 - 1.1e-07 32.3 0.1 3.1e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92862.1 - 3.2e-06 27.7 0.1 1.3e-05 25.7 0.1 2.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92862.1 - 8.9e-05 22.3 0.1 0.0002 21.2 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92862.1 - 0.0049 16.6 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG92862.1 - 0.15 11.8 0.2 0.28 10.9 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Peptidase_C48 PF02902.19 GBG92863.1 - 1.6e-16 60.9 0.9 3.2e-15 56.5 0.9 2.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Nbl1_Borealin_N PF10444.9 GBG92863.1 - 0.081 12.6 0.3 0.25 11.0 0.3 1.8 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal WxL PF13731.6 GBG92863.1 - 0.18 11.8 0.2 0.38 10.7 0.2 1.5 1 0 0 1 1 1 0 WxL domain surface cell wall-binding Pkinase_Tyr PF07714.17 GBG92864.1 - 8.3e-36 123.6 0.0 1.4e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG92864.1 - 1e-31 110.3 0.0 1.6e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GBG92864.1 - 0.033 13.0 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GBG92864.1 - 0.063 13.2 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RVT_1 PF00078.27 GBG92865.1 - 1.8e-05 24.4 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG92865.1 - 6.6e-05 23.4 0.0 0.00015 22.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92865.1 - 0.0012 19.5 0.0 0.0033 18.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92865.1 - 0.023 14.5 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG92865.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF4349 PF14257.6 GBG92866.1 - 0.32 10.4 2.3 0.71 9.3 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DDE_Tnp_4 PF13359.6 GBG92867.1 - 2.7e-32 111.6 0.0 4.6e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92867.1 - 1.2e-12 47.9 0.0 1.9e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG92867.1 - 0.006 16.3 0.4 3.3 7.3 0.1 2.4 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 GBG92867.1 - 0.082 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain Lipoxygenase PF00305.19 GBG92868.1 - 2e-123 413.2 0.0 1.2e-118 397.4 0.0 2.5 1 1 1 2 2 2 2 Lipoxygenase HSP70 PF00012.20 GBG92869.1 - 5.7e-138 460.7 0.0 6.9e-138 460.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG92869.1 - 4.7e-09 35.5 0.0 1.1e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GBG92869.1 - 0.0019 18.6 0.0 1.3 9.5 0.0 2.5 2 1 0 2 2 2 2 Cell division protein FtsA StbA PF06406.11 GBG92869.1 - 0.054 12.7 0.1 0.13 11.4 0.1 1.6 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.16 GBG92869.1 - 0.12 12.1 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain AAA_9 PF12781.7 GBG92869.1 - 0.23 10.6 0.9 0.56 9.3 0.2 1.8 2 0 0 2 2 2 0 ATP-binding dynein motor region HSP70 PF00012.20 GBG92870.1 - 3.6e-169 563.8 0.0 1.6e-87 294.1 0.0 3.5 2 2 0 2 2 2 2 Hsp70 protein TIM PF00121.18 GBG92870.1 - 3.8e-15 55.9 0.0 8.9e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Triosephosphate isomerase MreB_Mbl PF06723.13 GBG92870.1 - 1.9e-12 46.7 1.8 2.5e-05 23.3 0.9 2.9 2 1 0 2 2 2 2 MreB/Mbl protein Integrin_b_cyt PF08725.11 GBG92870.1 - 7.1 6.4 5.3 18 5.1 0.2 2.5 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain RVT_1 PF00078.27 GBG92871.1 - 8.1e-29 100.7 0.0 1.4e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92871.1 - 1e-28 99.3 0.0 2.3e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92871.1 - 8.3e-25 87.1 0.1 1.7e-24 86.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92871.1 - 6.2e-14 51.8 0.4 2e-13 50.2 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG92871.1 - 2.3e-10 40.7 0.0 5.2e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG92871.1 - 0.0093 16.2 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF2385 PF09539.10 GBG92871.1 - 0.11 13.0 0.2 1.5 9.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Rhamno_transf PF11316.8 GBG92871.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase Nop14 PF04147.12 GBG92872.1 - 0.12 10.6 28.4 0.14 10.4 28.4 1.0 1 0 0 1 1 1 0 Nop14-like family Serinc PF03348.15 GBG92872.1 - 0.18 10.7 0.9 0.21 10.5 0.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DNA_pol_phi PF04931.13 GBG92872.1 - 0.52 8.4 30.6 0.62 8.1 30.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Plasmodium_Vir PF05795.11 GBG92872.1 - 0.66 9.3 6.4 0.69 9.3 6.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDHD PF02862.17 GBG92872.1 - 1.6 8.8 4.0 1.8 8.7 4.0 1.2 1 0 0 1 1 1 0 DDHD domain BUD22 PF09073.10 GBG92872.1 - 4.6 6.5 34.0 5.8 6.1 34.0 1.0 1 0 0 1 1 1 0 BUD22 Connexin PF00029.19 GBG92872.1 - 7.6 6.2 7.3 10 5.8 7.3 1.4 1 0 0 1 1 1 0 Connexin DUF659 PF04937.15 GBG92873.1 - 1.1e-13 51.3 0.0 2.1e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) cwf21 PF08312.12 GBG92873.1 - 8.4e-05 22.6 0.7 0.58 10.4 0.1 2.4 2 0 0 2 2 2 2 cwf21 domain Mito_fiss_reg PF05308.11 GBG92874.1 - 1.1 9.3 4.2 9.6 6.2 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator N6_N4_Mtase PF01555.18 GBG92875.1 - 4.2e-06 26.6 0.0 5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 DNA methylase Neisseria_TspB PF05616.13 GBG92875.1 - 1.4 7.3 3.7 2 6.8 3.7 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Spc7 PF08317.11 GBG92877.1 - 0.025 13.4 31.8 0.069 12.0 12.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein HrpB7 PF09486.10 GBG92877.1 - 0.085 13.2 15.5 0.36 11.2 5.5 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) GAS PF13851.6 GBG92877.1 - 0.11 11.8 26.9 0.16 11.3 26.2 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sec34 PF04136.15 GBG92877.1 - 0.9 9.4 7.5 0.22 11.4 2.9 2.0 1 1 0 1 1 1 0 Sec34-like family HOOK PF05622.12 GBG92877.1 - 1.3 7.0 30.1 1.6 6.8 29.1 1.4 1 1 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.12 GBG92877.1 - 1.8 8.6 25.0 1.5 8.9 16.1 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 GBG92877.1 - 2.1 7.7 22.0 7.6 5.9 22.0 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 Cep57_MT_bd PF06657.13 GBG92877.1 - 5.5 7.5 21.6 0.53 10.8 5.6 3.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Lebercilin PF15619.6 GBG92877.1 - 7.5 6.2 37.0 2.1 7.9 16.0 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease EIN3 PF04873.13 GBG92878.1 - 6.9e-120 399.0 10.3 9.6e-120 398.6 10.3 1.2 1 0 0 1 1 1 1 Ethylene insensitive 3 DUF2841 PF11001.8 GBG92878.1 - 8.4e-06 25.9 3.4 9.7e-06 25.7 0.5 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2841) RVT_1 PF00078.27 GBG92879.1 - 1.5e-25 90.1 0.0 2.3e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92879.1 - 3.7e-22 78.3 0.0 7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92879.1 - 1.2e-18 67.3 0.0 2.6e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RepB-RCR_reg PF10723.9 GBG92880.1 - 0.013 15.4 0.0 0.037 14.0 0.0 1.8 1 0 0 1 1 1 0 Replication regulatory protein RepB PRKG1_interact PF15898.5 GBG92880.1 - 0.019 15.9 9.4 0.019 15.9 9.4 3.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain VIGSSK PF14773.6 GBG92880.1 - 0.028 14.5 0.2 0.16 12.1 0.0 2.4 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal FUSC PF04632.12 GBG92880.1 - 0.18 10.3 1.2 0.33 9.4 1.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family MMTV_SAg PF01054.17 GBG92880.1 - 0.34 10.4 6.1 1.2 8.6 1.8 2.5 1 1 1 2 2 2 0 Mouse mammary tumour virus superantigen Beta_helix PF13229.6 GBG92883.1 - 1.9e-07 31.0 7.7 5.1e-07 29.7 7.7 1.7 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GBG92883.1 - 0.0068 15.7 1.3 0.01 15.1 1.3 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) zinc_ribbon_10 PF10058.9 GBG92883.1 - 0.038 13.7 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Metal_resist PF13801.6 GBG92883.1 - 0.08 13.1 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Heavy-metal resistance Pentapeptide_3 PF13576.6 GBG92883.1 - 2.1 8.5 5.6 10 6.4 0.2 3.4 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Chlam_PMP PF02415.17 GBG92883.1 - 8 7.2 16.3 0.14 12.7 1.0 4.5 4 2 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Mito_fiss_reg PF05308.11 GBG92885.1 - 0.34 10.9 4.6 0.6 10.1 4.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 GBG92885.1 - 0.48 9.9 6.5 0.85 9.0 6.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 GBG92886.1 - 2.1e-24 86.3 0.0 2.7e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG92886.1 - 4e-07 29.6 0.0 5.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GBG92886.1 - 0.25 10.6 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Lyase_aromatic PF00221.19 GBG92888.1 - 3.5e-158 527.1 0.4 4e-158 526.9 0.4 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase zf-CCHC PF00098.23 GBG92889.1 - 2.6e-06 27.2 7.0 6.4e-06 26.0 7.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG92889.1 - 0.00045 19.9 4.8 0.0011 18.6 4.8 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 GBG92889.1 - 0.031 14.3 1.4 0.11 12.4 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92889.1 - 2.3 8.1 8.1 0.33 10.8 3.3 2.0 2 0 0 2 2 2 0 Zinc knuckle CDC45 PF02724.14 GBG92889.1 - 8.1 4.6 10.3 9.4 4.4 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG92889.1 - 9.4 4.9 4.9 11 4.7 4.9 1.2 1 0 0 1 1 1 0 Presenilin RT_RNaseH_2 PF17919.1 GBG92891.1 - 5.1e-26 90.6 0.0 1e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92891.1 - 2e-25 89.1 0.0 3.9e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92891.1 - 1.3e-19 70.0 0.2 4.6e-19 68.3 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GBG92891.1 - 0.0045 16.9 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GBG92891.1 - 0.067 13.4 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 GBG92892.1 - 2.5e-32 110.9 0.1 4e-32 110.2 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92892.1 - 4.9e-28 97.5 0.1 9.8e-28 96.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92892.1 - 1e-18 67.2 0.2 1.8e-18 66.4 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GBG92892.1 - 0.38 11.0 0.1 0.38 11.0 0.1 2.1 2 0 0 2 2 2 0 H2C2 zinc finger Exo_endo_phos PF03372.23 GBG92893.1 - 7.6e-06 25.6 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPP_enzyme_M_2 PF16582.5 GBG92893.1 - 0.00079 19.2 0.4 0.00079 19.2 0.4 2.1 3 0 0 3 3 3 1 Middle domain of thiamine pyrophosphate Exo_endo_phos_2 PF14529.6 GBG92893.1 - 0.03 14.2 0.0 0.091 12.6 0.0 1.9 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase CCT PF06203.14 GBG92894.1 - 5.6e-17 61.5 16.5 9.8e-17 60.7 16.5 1.4 1 0 0 1 1 1 1 CCT motif zf-B_box PF00643.24 GBG92894.1 - 3.8e-13 49.4 5.0 3.6e-06 27.0 0.1 2.2 1 1 1 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.5 GBG92894.1 - 0.0026 17.9 10.2 0.0038 17.4 2.0 2.5 1 1 1 2 2 2 2 Cytoplasmic polyadenylation element-binding protein ZZ domain SRF-TF PF00319.18 GBG92894.1 - 0.31 10.6 4.0 8.8 5.9 0.2 2.6 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) CBFB_NFYA PF02045.15 GBG92894.1 - 1.5 9.5 7.1 3.4 8.4 7.1 1.6 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B RT_RNaseH_2 PF17919.1 GBG92896.1 - 4.5e-31 106.8 0.0 1.9e-16 59.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92896.1 - 5.3e-31 107.9 0.0 8.5e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92896.1 - 1e-20 73.9 0.0 2.6e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SAPS PF04499.15 GBG92899.1 - 0.45 9.3 5.4 0.71 8.6 5.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LAP1C PF05609.12 GBG92899.1 - 1.1 8.3 16.4 2.7 7.0 0.1 2.3 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) DEAD PF00270.29 GBG92900.1 - 2.3e-31 108.9 0.0 7.7e-31 107.2 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GBG92900.1 - 3.4e-17 62.8 0.0 1.5e-16 60.7 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rve PF00665.26 GBG92900.1 - 2.2e-14 53.7 0.0 4.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain ResIII PF04851.15 GBG92900.1 - 1.8e-06 28.1 0.0 4.9e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 GBG92900.1 - 0.01 15.2 0.0 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_22 PF13401.6 GBG92900.1 - 0.032 14.5 0.1 20 5.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain RVT_1 PF00078.27 GBG92901.1 - 5.9e-17 61.9 0.1 1.1e-16 61.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG92901.1 - 3.8e-05 23.9 4.5 0.0026 18.0 0.0 4.1 4 0 0 4 4 4 1 Retrotransposon gag protein RVP_2 PF08284.11 GBG92901.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Endonuc_Holl PF10107.9 GBG92901.1 - 7.6 6.4 7.6 3.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Ldl_recept_a PF00057.18 GBG92902.1 - 1.4e-06 28.4 10.9 2.4e-06 27.6 10.9 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CbtA PF09490.10 GBG92902.1 - 0.0046 16.8 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) RT_RNaseH PF17917.1 GBG92903.1 - 1e-29 102.9 0.1 2.3e-29 101.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92903.1 - 4.4e-28 97.3 0.0 8.7e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92903.1 - 1.7e-17 63.2 0.3 4.5e-17 61.9 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92903.1 - 0.0028 17.9 0.0 0.0068 16.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG92903.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG92903.1 - 0.04 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Phage_GPO PF05929.11 GBG92903.1 - 0.057 13.0 0.1 0.057 13.0 0.1 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RT_RNaseH_2 PF17919.1 GBG92904.1 - 1.3e-23 82.9 0.0 2.3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92904.1 - 5.9e-23 81.2 0.0 1.1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92904.1 - 3.1e-11 43.2 0.1 4.9e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG92904.1 - 0.017 13.4 9.1 0.022 13.0 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG92904.1 - 0.17 10.1 12.3 0.23 9.7 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GBG92904.1 - 0.31 11.1 14.9 0.49 10.5 14.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GBG92904.1 - 0.38 10.1 12.8 0.52 9.7 12.8 1.1 1 0 0 1 1 1 0 SDA1 EF-hand_1 PF00036.32 GBG92905.1 - 1.5e-23 80.5 13.1 7.4e-08 31.4 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 GBG92905.1 - 2.7e-20 72.6 4.8 1.6e-13 50.9 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GBG92905.1 - 1.1e-19 68.6 8.6 1e-07 31.3 0.1 4.1 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 GBG92905.1 - 4.7e-17 61.6 11.4 2.4e-09 36.9 0.2 4.0 1 1 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 GBG92905.1 - 1.8e-14 53.8 0.3 4.4e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GBG92905.1 - 9.5e-11 40.7 5.7 0.00019 20.8 0.1 3.3 3 1 0 3 3 3 2 EF hand Caleosin PF05042.13 GBG92905.1 - 3.9e-05 23.6 0.5 0.13 12.2 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein UPF0154 PF03672.13 GBG92905.1 - 0.00083 19.3 0.5 1.3 9.1 0.0 3.0 5 0 0 5 5 4 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 GBG92905.1 - 0.0018 18.6 0.1 0.049 13.9 0.1 2.1 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 GBG92905.1 - 0.0028 18.5 0.0 0.0077 17.1 0.0 1.7 1 1 1 2 2 2 1 EF-hand domain FlgD PF03963.14 GBG92905.1 - 0.022 15.1 0.1 0.23 11.8 0.1 2.1 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF5580 PF17743.1 GBG92905.1 - 0.035 12.7 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Uteroglobin PF01099.17 GBG92905.1 - 0.041 14.2 0.2 0.11 12.9 0.1 1.7 1 1 0 1 1 1 0 Uteroglobin family RVT_1 PF00078.27 GBG92906.1 - 5.5e-27 94.7 0.1 8.2e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG92906.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG92907.1 - 0.0051 17.1 2.0 0.038 14.3 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein HsbA PF12296.8 GBG92907.1 - 4.5 7.7 9.3 2.7 8.4 3.5 2.7 2 1 1 3 3 3 0 Hydrophobic surface binding protein A Cys_Met_Meta_PP PF01053.20 GBG92908.1 - 1.2e-71 241.2 0.4 1.5e-71 241.0 0.4 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GBG92908.1 - 5.6e-06 25.6 0.1 7e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 GBG92908.1 - 0.00028 19.5 0.0 0.00034 19.3 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GBG92908.1 - 0.0019 17.1 0.1 0.0025 16.7 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein DUF3572 PF12096.8 GBG92908.1 - 0.061 13.5 0.3 0.31 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) Dabb PF07876.12 GBG92909.1 - 0.00017 22.1 0.7 0.3 11.7 0.2 2.4 1 1 1 2 2 2 2 Stress responsive A/B Barrel Domain VIT_2 PF13757.6 GBG92909.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Nop14 PF04147.12 GBG92909.1 - 0.12 10.5 8.4 0.13 10.5 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 GBG92909.1 - 1.4 6.9 4.4 1.7 6.6 4.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 GBG92909.1 - 5.3 6.3 11.0 9.1 5.5 11.0 1.4 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 GBG92909.1 - 9.1 6.2 9.6 15 5.5 9.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF659 PF04937.15 GBG92916.1 - 1.5e-16 60.6 0.0 2.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH PF17917.1 GBG92917.1 - 8.9e-23 80.6 0.0 2.8e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92917.1 - 2.1e-21 75.8 0.0 4.6e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92917.1 - 4.5e-19 68.3 1.7 1.1e-18 67.1 1.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG92917.1 - 1.4e-05 24.7 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG92917.1 - 0.00013 22.5 0.1 0.00028 21.4 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 GBG92917.1 - 0.0024 18.0 0.5 0.02 15.1 0.2 2.4 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease PF09668.10 GBG92917.1 - 0.0047 16.7 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG92917.1 - 0.0065 17.1 0.1 0.013 16.2 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92917.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DIOX_N PF14226.6 GBG92918.1 - 2.1e-05 25.3 0.0 3.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Nop14 PF04147.12 GBG92919.1 - 0.13 10.5 16.3 0.13 10.4 16.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG92919.1 - 1.4 8.3 26.6 1.8 7.9 26.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG92919.1 - 5.2 5.2 17.5 7.3 4.7 17.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GBG92919.1 - 9.7 4.8 6.5 12 4.6 6.5 1.1 1 0 0 1 1 1 0 Presenilin Integrase_H2C2 PF17921.1 GBG92922.1 - 1e-16 60.8 0.7 3.6e-16 59.0 0.7 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG92922.1 - 1.7e-16 60.1 0.0 3.5e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92922.1 - 3.9e-16 59.2 0.0 1e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG92922.1 - 2.5e-15 56.7 0.0 5.5e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG92922.1 - 0.00052 20.5 0.1 0.0011 19.4 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92922.1 - 0.014 16.0 0.0 0.032 14.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG92922.1 - 0.41 10.8 2.3 1 9.6 2.3 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG92923.1 - 3.4e-29 102.0 0.0 5e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92923.1 - 5.7e-19 68.0 0.0 1.4e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92923.1 - 3.4e-08 33.7 0.0 6.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG92923.1 - 0.026 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GBG92924.1 - 9.8e-07 28.6 1.2 1.8e-06 27.8 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG92924.1 - 0.007 16.2 1.8 0.029 14.2 0.2 2.3 2 0 0 2 2 2 1 Zinc knuckle YebO PF13974.6 GBG92924.1 - 0.81 9.8 5.8 1.9 8.6 5.8 1.6 1 0 0 1 1 1 0 YebO-like protein COR PF16095.5 GBG92925.1 - 4.4e-10 39.7 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 GBG92925.1 - 5.6e-08 33.0 0.0 5.3e-07 29.9 0.0 2.6 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GBG92925.1 - 0.0068 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 GBG92925.1 - 0.058 13.0 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Ras family Arf PF00025.21 GBG92925.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family RT_RNaseH_2 PF17919.1 GBG92926.1 - 2.1e-26 91.9 0.0 4.4e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92926.1 - 4.1e-26 91.3 0.0 8.1e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92926.1 - 1.9e-23 83.2 0.1 3e-23 82.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG92927.1 - 4.2e-22 78.4 0.0 1.1e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG92927.1 - 7.8e-22 77.2 0.0 1.7e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92927.1 - 3.7e-19 68.6 0.9 1e-18 67.1 0.9 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG92927.1 - 3.5e-09 36.5 0.0 6.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GBG92927.1 - 0.085 13.0 1.9 0.2 11.8 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG92928.1 - 4.3e-24 85.3 0.1 7.4e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92928.1 - 4.4e-17 62.0 0.0 1.2e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG92928.1 - 2.7e-06 27.2 1.4 5.3e-06 26.3 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GBG92928.1 - 2.3e-05 24.2 0.0 5.8e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG92928.1 - 5.7e-05 23.6 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG92928.1 - 0.00015 22.0 0.0 0.00047 20.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG92928.1 - 0.00034 21.2 0.0 0.0007 20.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92928.1 - 0.00083 19.1 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease CDC45 PF02724.14 GBG92928.1 - 0.67 8.2 14.7 1 7.6 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GBG92928.1 - 2 7.1 5.7 3.8 6.2 5.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 GBG92928.1 - 6.3 6.1 22.3 12 5.3 22.3 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG92928.1 - 9.8 5.4 26.1 19 4.4 26.1 1.4 1 0 0 1 1 1 0 BUD22 Apolipoprotein PF01442.18 GBG92931.1 - 0.0027 17.6 9.2 0.0042 17.0 9.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GBG92931.1 - 0.11 13.1 11.2 0.64 10.7 7.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mitofilin PF09731.9 GBG92931.1 - 0.16 10.8 10.0 0.19 10.6 10.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Podoplanin PF05808.11 GBG92931.1 - 0.16 12.0 2.4 0.19 11.9 2.4 1.1 1 0 0 1 1 1 0 Podoplanin Ax_dynein_light PF10211.9 GBG92931.1 - 0.36 10.8 6.5 0.38 10.7 6.5 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain YtxH PF12732.7 GBG92931.1 - 0.62 10.6 12.7 8.3 7.0 5.9 2.3 1 1 1 2 2 2 0 YtxH-like protein UPF0242 PF06785.11 GBG92931.1 - 0.83 9.7 5.1 0.9 9.6 5.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LEA_1 PF03760.15 GBG92931.1 - 2.1 9.0 25.4 6.8 7.4 19.7 2.4 2 1 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 EMC3_TMCO1 PF01956.16 GBG92931.1 - 4 7.1 5.5 4.1 7.1 5.5 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like HisKA_3 PF07730.13 GBG92931.1 - 7 7.3 7.4 11 6.6 2.3 2.4 1 1 2 3 3 3 0 Histidine kinase LEA_4 PF02987.16 GBG92932.1 - 5.4e-19 68.0 112.8 1.1e-05 25.5 15.7 8.3 3 2 4 8 8 8 7 Late embryogenesis abundant protein YtxH PF12732.7 GBG92932.1 - 1.2e-06 28.9 90.4 0.018 15.5 11.3 7.1 1 1 4 5 5 5 3 YtxH-like protein Apolipoprotein PF01442.18 GBG92932.1 - 1.5e-06 28.2 88.5 1.3e-05 25.1 32.1 3.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GBG92932.1 - 0.028 15.0 87.7 0.95 10.1 9.8 6.7 1 1 6 8 8 8 0 Bacterial protein of unknown function (DUF883) PMC2NT PF08066.12 GBG92932.1 - 2.5 8.9 6.6 2.1 9.1 0.6 3.2 2 2 0 2 2 2 0 PMC2NT (NUC016) domain DUF3584 PF12128.8 GBG92932.1 - 4.7 4.6 75.8 2.4 5.6 17.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Asp_protease PF09668.10 GBG92933.1 - 0.0023 17.7 0.3 0.004 16.9 0.3 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG92933.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG92933.1 - 0.063 13.0 0.2 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Hex_IIIa PF02455.16 GBG92933.1 - 0.22 10.3 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Mito_carr PF00153.27 GBG92934.1 - 1.6e-10 40.7 0.0 9.4e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial carrier protein EF-hand_7 PF13499.6 GBG92934.1 - 1e-05 25.9 0.1 1.8e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GBG92934.1 - 0.043 13.4 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 GBG92934.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 GBG92934.1 - 0.14 12.0 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair DUF659 PF04937.15 GBG92935.1 - 2.9e-23 82.4 0.0 4.7e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92935.1 - 0.00058 19.6 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF674 PF05056.12 GBG92936.1 - 9e-27 94.0 0.0 7.1e-14 51.5 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF674) rve PF00665.26 GBG92937.1 - 0.0083 16.3 0.7 0.022 15.0 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain zf-CCHC_3 PF13917.6 GBG92937.1 - 0.01 15.8 0.6 0.021 14.8 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG92937.1 - 0.014 15.7 0.8 0.1 12.9 0.0 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein SAM_KSR1 PF13543.6 GBG92937.1 - 0.12 12.5 0.0 1.4 9.0 0.0 2.5 2 1 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 zf-CCHC PF00098.23 GBG92937.1 - 0.75 10.0 4.7 1.7 8.9 4.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 GBG92937.1 - 1.5 8.6 3.5 3.8 7.3 3.5 1.7 1 0 0 1 1 1 0 Zinc knuckle AMP-binding PF00501.28 GBG92939.1 - 0.19 10.3 0.0 0.19 10.3 0.0 1.0 1 0 0 1 1 1 0 AMP-binding enzyme Integrase_H2C2 PF17921.1 GBG92942.1 - 2.7e-18 65.8 0.2 6.5e-18 64.6 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG92942.1 - 2.5e-11 43.8 0.0 3.1e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG92942.1 - 9.6e-08 31.8 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG92942.1 - 0.2 11.4 0.0 0.52 10.1 0.0 1.6 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF4201 PF13870.6 GBG92943.1 - 3.2 7.4 20.8 0.83 9.4 16.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Myb_DNA-bind_4 PF13837.6 GBG92944.1 - 0.00015 22.0 0.8 0.00024 21.4 0.8 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG92944.1 - 0.14 12.4 2.0 0.17 12.1 0.5 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain Peptidase_S10 PF00450.22 GBG92945.1 - 1.3e-123 413.5 0.0 4.5e-97 326.1 0.0 2.3 1 1 1 2 2 2 2 Serine carboxypeptidase Say1_Mug180 PF10340.9 GBG92945.1 - 0.24 10.2 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Ceramidase PF05875.12 GBG92946.1 - 0.081 12.3 0.3 0.11 11.8 0.3 1.1 1 0 0 1 1 1 0 Ceramidase DDE_Tnp_4 PF13359.6 GBG92947.1 - 1.4e-26 93.0 0.0 2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG92947.1 - 2.2e-11 43.7 0.0 3.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Peptidase_S10 PF00450.22 GBG92948.1 - 6.1e-92 309.2 0.0 9.9e-92 308.5 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase RVT_1 PF00078.27 GBG92949.1 - 7.5e-34 117.2 0.1 9e-34 116.9 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dabb PF07876.12 GBG92950.1 - 1.2e-10 41.8 0.0 1.4e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain RVT_1 PF00078.27 GBG92951.1 - 2.2e-29 102.6 0.0 2.9e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG92952.1 - 2.9e-33 115.3 0.0 4.3e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GBG92953.1 - 3.7e-11 43.0 0.0 1.6e-08 34.3 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG92954.1 - 0.00062 20.3 0.0 0.002 18.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92954.1 - 0.0022 18.6 0.0 0.0057 17.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RXLR PF16810.5 GBG92954.1 - 3.4 8.1 4.3 9.6 6.6 0.1 2.3 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity gag-asp_proteas PF13975.6 GBG92955.1 - 0.0006 20.3 0.0 0.0017 18.9 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG92955.1 - 0.0022 18.6 0.0 0.0049 17.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG92957.1 - 0.031 14.1 0.2 0.053 13.3 0.2 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG92957.1 - 0.036 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG92958.1 - 1.1e-18 67.0 0.2 2.3e-18 66.0 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG92958.1 - 3.4e-08 33.3 0.0 5.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG92958.1 - 4.3e-08 33.4 0.0 9.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain CBP_GIL PF10995.8 GBG92959.1 - 0.012 14.3 1.6 0.018 13.8 1.6 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis GIL Rota_NSP4 PF01452.16 GBG92959.1 - 1.3 8.7 7.4 1.9 8.1 7.4 1.2 1 0 0 1 1 1 0 Rotavirus non structural protein TSP_NTD PF17804.1 GBG92959.1 - 1.5 9.1 8.4 2.2 8.5 8.4 1.3 1 0 0 1 1 1 0 Tail specific protease N-terminal domain DUF5071 PF16804.5 GBG92959.1 - 7.3 6.9 10.0 0.7 10.2 5.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) Flavi_M PF01004.19 GBG92960.1 - 0.16 11.8 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M DUF4083 PF13314.6 GBG92962.1 - 0.24 11.4 0.5 0.74 9.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) AAA_2 PF07724.14 GBG92963.1 - 3.7e-53 180.2 0.0 3.5e-51 173.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GBG92963.1 - 1e-26 92.8 0.4 2.2e-26 91.8 0.4 1.5 1 0 0 1 1 1 1 AAA lid domain ClpB_D2-small PF10431.9 GBG92963.1 - 3e-24 84.9 0.2 8.8e-24 83.4 0.2 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GBG92963.1 - 6.4e-18 65.5 0.0 1.8e-08 34.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GBG92963.1 - 5.3e-15 55.6 0.2 6.7e-10 39.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 GBG92963.1 - 5.9e-13 48.7 4.3 2.9e-08 33.7 0.4 2.9 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 GBG92963.1 - 1.8e-10 41.5 6.8 0.00031 21.2 0.1 5.2 5 1 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 GBG92963.1 - 2.1e-07 31.3 0.8 0.34 11.2 0.1 4.6 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 GBG92963.1 - 6.5e-07 29.2 0.1 0.00067 19.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 GBG92963.1 - 2.3e-06 27.4 0.1 0.022 14.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 GBG92963.1 - 7.4e-05 23.3 0.6 0.24 11.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 GBG92963.1 - 0.00044 20.3 0.1 0.58 10.2 0.0 2.7 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 GBG92963.1 - 0.00051 19.8 0.3 1.8 8.3 0.0 4.0 4 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 GBG92963.1 - 0.00064 19.7 0.0 1.4 8.7 0.1 3.6 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 GBG92963.1 - 0.00068 19.3 0.1 0.38 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GBG92963.1 - 0.00079 18.8 0.0 0.03 13.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 GBG92963.1 - 0.001 18.5 0.2 0.82 9.0 0.0 3.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GBG92963.1 - 0.0019 17.7 0.1 0.46 10.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 GBG92963.1 - 0.0025 18.2 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 GBG92963.1 - 0.0031 17.4 0.2 0.39 10.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 GBG92963.1 - 0.0046 16.9 0.0 3 7.7 0.0 2.8 2 1 0 3 3 3 1 RsgA GTPase AAA_14 PF13173.6 GBG92963.1 - 0.0096 16.0 0.0 0.71 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GBG92963.1 - 0.0096 16.2 0.2 0.85 9.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 GBG92963.1 - 0.011 15.9 0.1 0.99 9.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 GBG92963.1 - 0.013 15.4 0.1 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 GBG92963.1 - 0.013 16.0 0.2 0.39 11.2 0.0 2.8 3 0 0 3 3 2 0 ABC transporter NB-ARC PF00931.22 GBG92963.1 - 0.021 14.0 0.0 4.6 6.3 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 GBG92963.1 - 0.021 15.1 0.5 10 6.4 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Torsin PF06309.11 GBG92963.1 - 0.021 14.9 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.6 GBG92963.1 - 0.068 12.9 0.5 9.7 5.9 0.0 3.5 2 1 1 3 3 3 0 AAA domain PhoH PF02562.16 GBG92963.1 - 0.091 12.2 0.0 15 4.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 GBG92963.1 - 0.14 12.1 0.0 4.5 7.2 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 GBG92963.1 - 0.25 10.9 0.7 1.4 8.5 0.0 2.4 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain DUF659 PF04937.15 GBG92964.1 - 3.9e-33 114.5 0.1 5.9e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92964.1 - 9.8e-05 22.1 0.3 0.00018 21.2 0.3 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4360 PF14273.6 GBG92967.1 - 3.7e-23 82.3 0.8 9.5e-23 81.0 0.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) BUD22 PF09073.10 GBG92968.1 - 0.011 15.2 19.2 0.013 14.9 19.2 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GBG92968.1 - 0.021 13.1 26.3 0.03 12.6 26.3 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG92968.1 - 0.052 13.0 24.3 0.074 12.5 24.3 1.2 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 GBG92968.1 - 0.45 9.8 20.6 0.68 9.3 20.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GBG92968.1 - 0.92 7.7 21.5 1.3 7.3 21.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG92968.1 - 0.99 7.4 30.4 1.4 6.9 30.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 GBG92968.1 - 1.3 9.0 21.1 1.9 8.4 21.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2201_N PF13203.6 GBG92968.1 - 1.4 8.5 8.6 2.4 7.7 8.6 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF913 PF06025.12 GBG92968.1 - 1.6 7.7 7.1 2.4 7.0 7.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFB6 PF17110.5 GBG92968.1 - 4.2 7.1 9.9 8.4 6.1 9.9 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Zip PF02535.22 GBG92968.1 - 4.7 6.3 6.1 7 5.8 6.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 GBG92968.1 - 9.5 5.3 13.0 15 4.7 13.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4045 PF13254.6 GBG92969.1 - 0.031 13.9 12.7 0.041 13.5 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Retrotrans_gag PF03732.17 GBG92969.1 - 0.095 13.0 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Presenilin PF01080.17 GBG92969.1 - 0.19 10.5 7.4 0.23 10.2 7.4 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GBG92969.1 - 5.1 5.3 15.9 6.4 4.9 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 GBG92970.1 - 2.3e-28 99.2 0.1 5e-28 98.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG92970.1 - 0.011 16.0 0.1 0.082 13.2 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein SlyX PF04102.12 GBG92970.1 - 1.1 9.9 7.5 0.94 10.1 0.5 3.6 4 0 0 4 4 4 0 SlyX ATG16 PF08614.11 GBG92970.1 - 5.6 7.1 12.1 5.8 7.1 4.6 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 GBG92971.1 - 0.016 15.3 12.0 0.016 15.3 12.0 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cellulose_synt PF03552.14 GBG92971.1 - 0.39 9.2 1.2 0.7 8.3 1.2 1.3 1 0 0 1 1 1 0 Cellulose synthase LMBR1 PF04791.16 GBG92971.1 - 0.58 9.0 6.5 0.98 8.2 6.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein RVT_1 PF00078.27 GBG92972.1 - 1.7e-09 37.5 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lipocalin PF00061.23 GBG92973.1 - 1.2e-07 32.1 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 GBG92973.1 - 1.9e-05 24.6 0.0 3e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Lipocalin-like domain Prok_Ub PF14454.6 GBG92973.1 - 0.02 14.5 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin Mitofilin PF09731.9 GBG92975.1 - 3 6.6 27.7 3.5 6.4 27.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein XRN_M PF17846.1 GBG92975.1 - 9.9 5.0 17.5 11 4.8 17.5 1.0 1 0 0 1 1 1 0 Xrn1 helical domain MULE PF10551.9 GBG92976.1 - 3.3e-17 62.7 0.0 5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 GBG92976.1 - 0.0067 15.3 0.0 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DUF659 PF04937.15 GBG92977.1 - 1.5e-22 80.1 0.0 3.1e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 GBG92977.1 - 0.00059 20.1 0.2 0.00059 20.1 0.2 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein MULE PF10551.9 GBG92978.1 - 3.9e-16 59.2 0.0 7.9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 GBG92978.1 - 9.3e-08 32.0 0.5 6.1e-07 29.3 0.2 2.4 2 0 0 2 2 2 1 MuDR family transposase Transposase_mut PF00872.18 GBG92978.1 - 0.0089 14.9 0.1 0.015 14.2 0.1 1.4 1 0 0 1 1 1 1 Transposase, Mutator family PTPS PF01242.19 GBG92978.1 - 0.042 13.8 0.1 5.2 7.1 0.0 2.6 2 1 1 3 3 3 0 6-pyruvoyl tetrahydropterin synthase Ribosomal_S17e PF00833.18 GBG92978.1 - 0.85 9.6 4.6 3.2 7.7 0.6 3.2 3 1 1 4 4 4 0 Ribosomal S17 SCAB-Ig PF16709.5 GBG92980.1 - 0.00055 19.9 0.3 0.026 14.6 0.0 3.0 3 0 0 3 3 3 1 Ig domain of plant-specific actin-binding protein RVT_1 PF00078.27 GBG92982.1 - 6.7e-28 97.7 0.1 1e-27 97.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92982.1 - 5.6e-19 68.0 0.0 4.1e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92982.1 - 1.9e-07 31.3 0.0 4.2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG92983.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 GBG92984.1 - 3.2e-30 105.3 0.1 7.3e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92984.1 - 1e-27 96.1 0.0 2.9e-27 94.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92984.1 - 2.3e-25 88.9 0.0 6.8e-25 87.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG92984.1 - 0.00049 20.3 1.7 0.0024 18.1 0.2 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein LPP PF04728.13 GBG92984.1 - 0.11 13.0 2.5 4.8 7.6 0.1 3.3 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF659 PF04937.15 GBG92985.1 - 8.3e-19 67.9 0.0 1.5e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG92985.1 - 0.004 16.9 0.1 0.0089 15.8 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TrkA_C PF02080.21 GBG92985.1 - 0.076 12.9 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 TrkA-C domain Pkinase PF00069.25 GBG92987.1 - 6.2e-37 127.4 0.0 1e-36 126.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG92987.1 - 1.1e-36 126.5 0.0 1.4e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 GBG92987.1 - 5.1e-27 94.8 0.0 9.3e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92987.1 - 1.1e-09 38.3 0.0 8.9e-05 22.5 0.0 2.9 2 1 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG92987.1 - 1.2e-09 38.1 0.0 1.2e-09 38.1 0.0 2.8 4 0 0 4 4 4 1 Integrase zinc binding domain rve PF00665.26 GBG92987.1 - 8.6e-08 32.4 0.0 2.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG92987.1 - 2.2e-05 24.6 0.0 5.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG92987.1 - 0.00013 22.2 0.0 0.00034 20.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase_fungal PF17667.1 GBG92987.1 - 0.0031 16.3 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PQQ_3 PF13570.6 GBG92987.1 - 0.006 17.0 0.5 0.92 10.1 0.0 3.7 3 0 0 3 3 3 1 PQQ-like domain Pkinase_Tyr PF07714.17 GBG92988.1 - 1.3e-31 109.8 0.0 2.4e-31 108.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG92988.1 - 7.2e-31 107.5 0.0 9.9e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 GBG92988.1 - 0.00025 21.0 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Cadherin_C_2 PF16492.5 GBG92988.1 - 0.097 13.4 0.0 0.27 12.0 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Pkinase PF00069.25 GBG92990.1 - 8.4e-18 64.7 0.0 2.6e-11 43.4 0.0 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG92990.1 - 3.8e-15 55.9 0.0 5.5e-06 25.9 0.0 3.2 1 1 2 3 3 3 3 Protein tyrosine kinase 2OG-FeII_Oxy_2 PF13532.6 GBG92992.1 - 3.8e-08 33.8 0.0 1.3e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RVT_1 PF00078.27 GBG92993.1 - 1.4e-28 99.9 0.0 2.4e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG92993.1 - 5.5e-27 93.7 0.0 1.9e-26 92.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92993.1 - 5.3e-23 81.3 0.0 1.6e-22 79.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG92993.1 - 6.4e-08 33.1 0.0 2.5e-07 31.2 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG92993.1 - 3.6e-07 30.6 0.0 1.2e-06 29.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG92993.1 - 2.2e-05 24.2 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG92993.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG92994.1 - 1.1e-24 86.4 0.0 3e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG92994.1 - 8.8e-22 77.4 0.0 2e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG92994.1 - 6.2e-19 68.4 0.2 3.8e-18 65.8 0.0 2.4 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG92994.1 - 3.1e-06 27.7 0.0 9.9e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG92994.1 - 4.7e-06 26.4 0.0 9.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG92994.1 - 6.9e-06 26.6 0.0 3.8e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG92994.1 - 3.6e-05 24.0 14.7 0.0001 22.5 0.1 4.9 4 0 0 4 4 4 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 GBG92994.1 - 5.4e-05 23.2 0.1 0.00014 21.9 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG92994.1 - 0.0029 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Gp58 PF07902.11 GBG92994.1 - 0.65 8.2 4.2 0.99 7.6 4.2 1.1 1 0 0 1 1 1 0 gp58-like protein NPV_P10 PF05531.12 GBG92994.1 - 2.7 8.5 7.5 17 6.0 1.0 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 GBG92994.1 - 8.4 6.8 15.8 0.081 13.2 3.7 3.3 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RVT_1 PF00078.27 GBG92995.1 - 1.6e-29 103.1 0.0 2.8e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG92995.1 - 0.0012 19.1 0.5 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein ALIX_LYPXL_bnd PF13949.6 GBG92995.1 - 0.21 10.9 1.6 0.57 9.4 1.6 1.7 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Phycobilisome PF00502.19 GBG92995.1 - 0.21 11.5 0.6 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Phycobilisome protein SepSecS PF05889.13 GBG92996.1 - 0.82 8.3 3.3 0.99 8.0 3.3 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Mem_trans PF03547.18 GBG92996.1 - 1.4 7.3 4.1 1.8 6.9 4.1 1.1 1 0 0 1 1 1 0 Membrane transport protein IncFII_repA PF02387.15 GBG92996.1 - 1.7 7.8 10.5 0.46 9.7 7.2 1.6 2 0 0 2 2 2 0 IncFII RepA protein family FapA PF03961.13 GBG92996.1 - 3.1 6.3 12.1 3.2 6.3 12.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A NPAT_C PF15712.5 GBG92996.1 - 5.8 5.4 12.5 6.3 5.3 12.5 1.1 1 0 0 1 1 1 0 NPAT C terminus zf-FCS PF06467.14 GBG92998.1 - 0.37 10.8 1.7 0.75 9.8 1.7 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Cwf_Cwc_15 PF04889.12 GBG93000.1 - 0.0044 16.8 1.5 0.0066 16.2 1.5 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG93000.1 - 0.026 12.9 5.9 0.03 12.6 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG93000.1 - 0.74 7.9 5.4 0.86 7.7 5.4 1.0 1 0 0 1 1 1 0 Nop14-like family N6_N4_Mtase PF01555.18 GBG93001.1 - 0.13 12.0 0.1 0.35 10.6 0.1 1.8 1 0 0 1 1 1 0 DNA methylase RT_RNaseH PF17917.1 GBG93002.1 - 6.2e-30 103.6 0.0 1.5e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93002.1 - 8.5e-22 77.1 0.0 2.7e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG93002.1 - 2.7e-06 27.2 0.0 7.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG93002.1 - 1.5e-05 25.5 0.0 3.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 GBG93002.1 - 0.0017 17.9 0.4 0.028 13.9 0.1 2.3 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG93002.1 - 0.0022 18.5 0.0 0.0067 17.0 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 GBG93002.1 - 0.0029 17.4 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG93002.1 - 0.0048 16.7 0.0 0.07 12.9 0.1 2.5 2 1 0 2 2 2 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG93003.1 - 1.7e-35 121.0 0.1 3.1e-35 120.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93003.1 - 4.9e-32 110.3 0.1 9.6e-32 109.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93003.1 - 2.2e-12 47.0 0.2 4e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cutinase PF01083.22 GBG93005.1 - 0.047 13.6 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Cutinase Retrotrans_gag PF03732.17 GBG93008.1 - 0.34 11.2 0.0 0.34 11.2 0.0 2.7 4 0 0 4 4 4 0 Retrotransposon gag protein IclR PF01614.18 GBG93008.1 - 2.5 7.9 9.2 0.69 9.8 3.3 2.4 2 0 0 2 2 2 0 Bacterial transcriptional regulator RVP_2 PF08284.11 GBG93010.1 - 4.3e-09 36.2 0.0 1.6e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG93010.1 - 1.4e-08 35.3 0.0 3.6e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93010.1 - 2.6e-06 27.9 0.0 7.9e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2730 PF10805.8 GBG93010.1 - 0.017 15.2 0.7 0.16 12.1 0.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) SlyX PF04102.12 GBG93010.1 - 0.02 15.5 10.0 0.049 14.3 0.1 3.4 4 0 0 4 4 4 0 SlyX Asp_protease PF09668.10 GBG93010.1 - 0.023 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TRPM_tetra PF16519.5 GBG93010.1 - 0.43 10.7 5.2 2.2 8.5 0.5 3.2 3 1 0 3 3 3 0 Tetramerisation domain of TRPM DUF1664 PF07889.12 GBG93010.1 - 0.79 9.8 2.6 7.4 6.6 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RT_RNaseH PF17917.1 GBG93011.1 - 3e-20 72.4 0.0 5.3e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93011.1 - 2.3e-19 69.3 0.0 4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG93011.1 - 3.5e-05 24.3 0.0 6.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 GBG93011.1 - 0.0029 17.8 0.0 0.0085 16.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 GBG93011.1 - 0.013 16.1 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG93011.1 - 0.059 13.2 0.6 0.1 12.4 0.6 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 GBG93011.1 - 0.19 12.0 0.0 0.57 10.5 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease TEX19 PF15553.6 GBG93011.1 - 1.3 9.0 4.0 0.49 10.4 0.1 2.3 2 0 0 2 2 2 0 Testis-expressed protein 19 Complex1_49kDa PF00346.19 GBG93012.1 - 0.037 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF659 PF04937.15 GBG93013.1 - 1.7e-34 118.9 0.0 2.8e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2828 PF11443.8 GBG93014.1 - 0.54 8.3 8.1 0.64 8.0 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EIIBC-GUT_N PF03612.14 GBG93014.1 - 1.9 8.2 10.3 4.6 6.9 5.3 2.8 3 1 1 4 4 4 0 Sorbitol phosphotransferase enzyme II N-terminus DDE_Tnp_4 PF13359.6 GBG93015.1 - 4.1e-19 68.8 0.0 5.9e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG93015.1 - 0.00012 21.8 0.1 0.0004 20.0 0.1 1.7 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 GBG93015.1 - 0.033 14.5 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 GBG93015.1 - 0.055 13.1 0.0 2.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Transposase DDE domain Metallophos PF00149.28 GBG93016.1 - 4.5e-30 105.7 0.1 9e-30 104.7 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GBG93016.1 - 0.017 15.3 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Borrelia_P83 PF05262.11 GBG93017.1 - 0.011 14.3 33.0 0.07 11.6 33.7 1.8 2 0 0 2 2 2 0 Borrelia P83/100 protein AF-4 PF05110.13 GBG93017.1 - 4.8 5.1 39.1 6.2 4.8 39.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Amino_oxidase PF01593.24 GBG93018.1 - 2.8e-63 214.8 0.0 3.4e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase RVT_1 PF00078.27 GBG93019.1 - 8.7e-38 130.0 0.1 1.5e-37 129.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG93019.1 - 2.1e-29 101.9 0.0 4.5e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93019.1 - 2.2e-29 101.4 0.0 6.8e-29 99.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG93019.1 - 2.7e-07 30.4 0.0 6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG93019.1 - 1.4e-06 28.8 0.0 3.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93019.1 - 0.00015 22.2 0.0 0.00053 20.5 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG93019.1 - 0.00049 20.2 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1758 PF05585.12 GBG93019.1 - 0.0018 18.1 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 GBG93019.1 - 0.0052 16.6 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease Mrr_N PF14338.6 GBG93019.1 - 0.88 9.7 5.7 23 5.2 2.5 3.1 3 0 0 3 3 3 0 Mrr N-terminal domain BUD22 PF09073.10 GBG93020.1 - 0.0021 17.5 12.2 0.0021 17.5 12.2 1.1 1 0 0 1 1 1 1 BUD22 RNA12 PF10443.9 GBG93020.1 - 0.0066 15.2 0.5 0.009 14.8 0.5 1.1 1 0 0 1 1 1 1 RNA12 protein PPP4R2 PF09184.11 GBG93020.1 - 0.034 13.7 15.5 0.043 13.4 15.5 1.1 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 GBG93020.1 - 0.038 14.0 11.6 0.037 14.0 11.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 GBG93020.1 - 0.047 12.6 8.4 0.057 12.3 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 GBG93020.1 - 0.49 8.6 14.2 0.54 8.5 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 GBG93020.1 - 4.6 6.1 6.6 6 5.7 6.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 GBG93020.1 - 4.7 5.3 26.2 5.6 5.0 26.2 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 GBG93020.1 - 5.6 6.3 22.2 7.6 5.8 22.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pkinase PF00069.25 GBG93021.1 - 9.6e-46 156.3 0.0 1.6e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG93021.1 - 2.2e-24 86.2 0.0 5.5e-22 78.3 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GBG93021.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GBG93021.1 - 0.11 11.8 0.1 3 7.1 0.4 2.5 2 1 0 2 2 2 0 Kinase-like Pkinase PF00069.25 GBG93022.1 - 2.7e-34 118.8 0.0 4.3e-34 118.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG93022.1 - 2.4e-17 63.1 0.1 6.9e-14 51.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GBG93022.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 GBG93022.1 - 0.14 11.5 0.4 2.1 7.6 0.4 2.1 1 1 0 1 1 1 0 Kinase-like Asp_protease_2 PF13650.6 GBG93023.1 - 0.012 16.2 0.1 0.023 15.3 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG93023.1 - 0.11 13.0 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 GBG93025.1 - 4.9e-17 62.1 0.0 1.2e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93025.1 - 7.9e-11 41.9 0.1 1.7e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG93025.1 - 4.6e-10 39.4 0.0 1.2e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG93025.1 - 0.074 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain MAM33 PF02330.16 GBG93026.1 - 5.7e-26 91.8 0.0 5.8e-17 62.3 0.0 3.9 2 1 2 4 4 4 2 Mitochondrial glycoprotein Ribosomal_60s PF00428.19 GBG93026.1 - 0.0015 19.1 22.0 0.0063 17.1 5.2 3.2 3 0 0 3 3 3 2 60s Acidic ribosomal protein WRNPLPNID PF15017.6 GBG93026.1 - 0.02 15.8 12.2 0.54 11.2 1.5 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Myc_N PF01056.18 GBG93026.1 - 0.045 13.7 3.8 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Spt5_N PF11942.8 GBG93026.1 - 0.34 11.9 16.1 1.5 9.8 1.7 2.5 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal FYDLN_acid PF09538.10 GBG93026.1 - 0.36 11.5 3.1 2.4 8.9 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF4746 PF15928.5 GBG93026.1 - 0.43 10.0 2.1 2 7.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) BSP_II PF05432.11 GBG93026.1 - 0.97 9.1 13.6 1.2 8.8 2.1 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Radial_spoke PF04712.12 GBG93026.1 - 3.9 6.3 7.1 2.8 6.8 0.9 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein CompInhib_SCIN PF11546.8 GBG93027.1 - 0.0026 17.8 0.1 0.003 17.6 0.1 1.0 1 0 0 1 1 1 1 Staphylococcal complement inhibitor SCIN RT_RNaseH_2 PF17919.1 GBG93029.1 - 3.4e-15 55.9 0.0 9.7e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93029.1 - 9.5e-13 48.3 0.0 3.4e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93029.1 - 1e-07 31.7 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG93029.1 - 5.8e-06 26.8 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93029.1 - 2.7e-05 24.7 0.0 5.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG93029.1 - 0.047 13.5 0.7 0.093 12.5 0.7 1.4 1 0 0 1 1 1 0 Aspartyl protease PGA2 PF07543.12 GBG93029.1 - 1 9.4 9.4 4.1 7.4 9.4 2.0 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF4360 PF14273.6 GBG93030.1 - 8.4e-38 130.0 0.2 9.7e-38 129.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RT_RNaseH_2 PF17919.1 GBG93031.1 - 1.6e-21 76.2 0.0 2.8e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93031.1 - 3.7e-17 62.5 0.0 6.8e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93031.1 - 8.5e-10 38.5 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG93034.1 - 1e-16 61.2 0.0 1.7e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG93035.1 - 1.7e-32 111.4 0.0 3.7e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93035.1 - 4.8e-30 104.7 0.1 9e-30 103.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG93035.1 - 2.3e-28 98.6 0.1 4.9e-28 97.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93035.1 - 1.1e-17 63.9 0.4 2.6e-17 62.6 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG93035.1 - 7.9e-07 29.3 0.0 2.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG93035.1 - 0.0036 17.5 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger TBCA PF02970.16 GBG93036.1 - 0.027 14.8 0.6 0.051 13.9 0.6 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A EPO_TPO PF00758.18 GBG93036.1 - 0.18 11.8 1.6 0.19 11.7 0.1 1.7 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin DUF2630 PF10944.8 GBG93036.1 - 0.72 10.4 0.1 0.72 10.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2630) DUF3527 PF12043.8 GBG93037.1 - 0.029 14.0 1.3 0.042 13.4 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) L27_2 PF09045.10 GBG93037.1 - 0.12 12.4 2.3 0.34 10.9 2.2 1.9 1 1 0 1 1 1 0 L27_2 Nsp1_C PF05064.13 GBG93037.1 - 0.12 12.1 8.9 0.081 12.7 0.6 3.5 2 2 1 3 3 3 0 Nsp1-like C-terminal region DUF1664 PF07889.12 GBG93037.1 - 1.8 8.6 6.7 1.2 9.2 4.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RT_RNaseH_2 PF17919.1 GBG93038.1 - 6.4e-21 74.3 0.0 1.3e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG93038.1 - 5.2e-15 55.7 0.1 1.1e-14 54.6 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 GBG93038.1 - 7.5e-10 39.0 0.0 1.6e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5066 PF16728.5 GBG93039.1 - 0.025 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) Dynamin_N PF00350.23 GBG93039.1 - 0.09 12.8 1.3 0.14 12.2 0.1 1.9 2 1 0 2 2 2 0 Dynamin family ApoO PF09769.9 GBG93039.1 - 0.3 11.1 1.4 13 5.7 0.2 3.2 4 1 1 5 5 5 0 Apolipoprotein O GAS PF13851.6 GBG93039.1 - 5.4 6.3 12.2 0.19 11.1 2.9 2.9 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding Myb_DNA-bind_4 PF13837.6 GBG93040.1 - 1.7e-07 31.5 0.2 3.2e-07 30.6 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4360 PF14273.6 GBG93041.1 - 1.9e-38 132.1 1.2 2.2e-38 131.9 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG93042.1 - 2.6e-45 154.5 0.3 3.5e-45 154.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 GBG93043.1 - 5.7e-38 130.5 0.3 6.5e-38 130.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF3752 PF12572.8 GBG93045.1 - 5.8e-23 82.1 11.5 5.8e-23 82.1 11.5 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3752) DnaJ PF00226.31 GBG93045.1 - 5.9e-16 58.3 0.2 1.8e-15 56.8 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Macoilin PF09726.9 GBG93045.1 - 0.094 11.3 15.0 0.0087 14.7 7.8 2.4 2 0 0 2 2 2 0 Macoilin family CDRT4 PF15213.6 GBG93045.1 - 6.6 7.3 13.4 25 5.5 13.4 1.9 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein WD40 PF00400.32 GBG93046.1 - 8e-14 51.8 17.7 0.031 15.2 0.1 10.1 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG93046.1 - 8.4e-05 22.8 0.0 6.1 7.2 0.0 5.3 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain FN3_7 PF18447.1 GBG93047.1 - 0.05 13.9 0.0 0.19 12.0 0.1 1.9 2 0 0 2 2 2 0 Fibronectin type III domain RVT_1 PF00078.27 GBG93048.1 - 2.2e-12 47.0 0.0 3.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Protocadherin PF08374.11 GBG93049.1 - 0.81 9.6 2.5 1.9 8.4 2.5 1.6 1 0 0 1 1 1 0 Protocadherin RVT_1 PF00078.27 GBG93050.1 - 1.4e-12 47.6 0.0 2.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1441 PF07278.11 GBG93050.1 - 0.091 12.7 0.6 9.3 6.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1441) RT_RNaseH_2 PF17919.1 GBG93051.1 - 3e-27 94.6 0.0 8.3e-27 93.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93051.1 - 3e-25 88.5 0.0 6e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93051.1 - 1.2e-17 64.1 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 GBG93051.1 - 0.22 11.8 10.7 0.41 10.9 10.7 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Cwf_Cwc_15 PF04889.12 GBG93051.1 - 0.69 9.6 21.6 9.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3807 PF12720.7 GBG93051.1 - 3.2 8.0 14.3 6.7 7.0 14.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF659 PF04937.15 GBG93052.1 - 3e-14 53.2 0.0 4.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG93052.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Pkinase_Tyr PF07714.17 GBG93053.1 - 5.2e-13 48.9 0.0 8.2e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG93053.1 - 4.7e-09 36.0 0.0 7.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain BPL_LplA_LipB PF03099.19 GBG93054.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 1 0 1 1 1 0 Biotin/lipoate A/B protein ligase family CemA PF03040.14 GBG93054.1 - 6.1 6.7 7.2 11 5.9 7.2 1.5 1 0 0 1 1 1 0 CemA family DUF3629 PF12302.8 GBG93054.1 - 6.9 6.0 8.4 13 5.2 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) RVT_1 PF00078.27 GBG93055.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG93055.1 - 0.00037 20.7 0.4 0.0011 19.2 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG93056.1 - 6.6e-28 97.7 0.1 1.7e-27 96.4 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93056.1 - 1.5e-24 85.9 0.0 8.7e-24 83.5 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93056.1 - 7.6e-23 80.8 0.0 1.9e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93056.1 - 1.6e-07 31.3 0.1 6.3e-07 29.4 0.1 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 GBG93057.1 - 1.8e-25 88.8 0.0 1.1e-24 86.3 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93057.1 - 6.5e-25 87.4 0.0 2e-24 85.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93057.1 - 7.2e-18 64.5 0.6 1.8e-17 63.2 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG93057.1 - 0.00066 19.5 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 GBG93057.1 - 0.00089 19.5 0.1 0.0031 17.8 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GBG93057.1 - 0.0039 17.8 0.0 0.011 16.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93057.1 - 0.0051 17.3 0.0 0.02 15.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG93057.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Cwf_Cwc_15 PF04889.12 GBG93058.1 - 0.0043 16.8 0.6 0.0053 16.5 0.6 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG93058.1 - 0.069 11.4 5.9 0.076 11.3 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG93058.1 - 0.89 7.7 6.0 1 7.5 6.0 1.0 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG93060.1 - 5.9e-35 120.8 0.2 1.4e-34 119.6 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93060.1 - 1.4e-15 57.2 0.2 6.3e-15 55.0 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93060.1 - 2.8e-05 24.3 0.1 0.00031 21.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 GBG93060.1 - 0.044 13.7 0.3 0.044 13.7 0.3 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain CCDC85 PF10226.9 GBG93060.1 - 0.15 11.7 0.1 0.38 10.4 0.1 1.6 1 0 0 1 1 1 0 CCDC85 family Aldo_ket_red PF00248.21 GBG93061.1 - 2.6e-53 181.1 0.0 4.3e-53 180.4 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family RVT_1 PF00078.27 GBG93062.1 - 4.5e-59 199.6 0.5 4.9e-29 101.4 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93062.1 - 2.6e-26 91.6 0.0 5.9e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93062.1 - 2.5e-25 88.8 0.0 5.5e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93062.1 - 2.1e-18 66.2 0.1 4.7e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain APG17 PF04108.12 GBG93062.1 - 0.0033 16.6 0.1 1.6 7.8 0.0 3.0 2 1 1 3 3 3 2 Autophagy protein Apg17 CDH1_2_SANT_HL1 PF18375.1 GBG93062.1 - 0.069 13.8 1.0 12 6.7 0.0 3.0 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 zf-H2C2 PF09337.10 GBG93062.1 - 0.097 12.9 0.0 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger CLIP1_ZNF PF16641.5 GBG93062.1 - 0.5 10.3 2.6 1.3 9.0 2.6 1.7 1 0 0 1 1 1 0 CLIP1 zinc knuckle GNAT_acetyltran PF12746.7 GBG93064.1 - 0.069 12.7 0.7 0.58 9.7 0.1 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase DUF659 PF04937.15 GBG93065.1 - 2.2e-30 105.5 0.1 3.5e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG93067.1 - 1.6e-35 122.7 0.2 2.9e-35 121.8 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93067.1 - 2e-29 101.6 0.0 8.9e-29 99.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93067.1 - 5.2e-26 91.0 0.0 1.1e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Zw10 PF06248.13 GBG93068.1 - 0.1 11.1 0.0 0.47 9.0 0.0 1.9 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 F-box PF00646.33 GBG93068.1 - 0.77 9.7 5.6 3.6 7.6 0.0 3.6 4 0 0 4 4 4 0 F-box domain DUF1479 PF07350.12 GBG93069.1 - 0.22 10.2 6.6 0.25 10.0 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) DUF4569 PF15133.6 GBG93069.1 - 0.35 10.6 9.2 0.41 10.3 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Prothymosin PF03247.14 GBG93069.1 - 0.59 10.6 23.2 0.79 10.2 23.2 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family SepSecS PF05889.13 GBG93069.1 - 0.77 8.4 3.6 0.89 8.2 3.6 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS IncFII_repA PF02387.15 GBG93069.1 - 1.4 8.1 7.3 1.7 7.8 7.3 1.1 1 0 0 1 1 1 0 IncFII RepA protein family PepSY_TM_like_2 PF16357.5 GBG93069.1 - 3.8 7.5 4.3 4.2 7.3 4.3 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like FapA PF03961.13 GBG93069.1 - 5.5 5.5 11.7 5.8 5.4 11.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A PA26 PF04636.13 GBG93069.1 - 6 5.7 9.3 6.6 5.5 9.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CemA PF03040.14 GBG93069.1 - 9 6.2 10.5 11 5.8 10.5 1.2 1 0 0 1 1 1 0 CemA family IU_nuc_hydro PF01156.19 GBG93070.1 - 9.3e-43 146.9 0.0 1.1e-42 146.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ECH_1 PF00378.20 GBG93071.1 - 2e-52 178.0 0.4 2.5e-52 177.7 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GBG93071.1 - 1.1e-27 97.5 0.1 2e-27 96.6 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ABC1 PF03109.16 GBG93072.1 - 1.2e-34 119.1 0.0 1.8e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Thioredoxin PF00085.20 GBG93073.1 - 1.7e-16 60.1 0.0 2.4e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GBG93073.1 - 0.00028 20.4 0.0 0.00037 19.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GBG93073.1 - 0.0027 18.0 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GBG93073.1 - 0.0038 17.7 0.0 0.0064 16.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GBG93073.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 GBG93073.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 GBG93073.1 - 0.22 11.7 0.1 0.35 11.0 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin Evr1_Alr PF04777.13 GBG93074.1 - 8.8e-21 74.3 0.3 5.5e-20 71.7 0.5 2.1 2 0 0 2 2 2 1 Erv1 / Alr family S4_2 PF13275.6 GBG93075.1 - 7.6 6.4 6.3 2.1 8.2 0.3 3.2 3 1 0 3 3 3 0 S4 domain DUF2407_C PF13373.6 GBG93076.1 - 0.028 14.6 4.7 0.079 13.1 4.7 1.8 1 0 0 1 1 1 0 DUF2407 C-terminal domain zf-CCHC PF00098.23 GBG93076.1 - 0.032 14.3 0.6 0.077 13.1 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1682 PF07946.14 GBG93076.1 - 0.57 9.3 18.3 1.2 8.2 18.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) BT1 PF03092.16 GBG93076.1 - 1.7 6.8 7.5 2.6 6.2 7.5 1.2 1 0 0 1 1 1 0 BT1 family DUF4801 PF16059.5 GBG93077.1 - 0.052 13.5 1.2 0.13 12.3 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4801) DUF3381 PF11861.8 GBG93077.1 - 0.13 12.1 10.2 0.19 11.5 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Nop14 PF04147.12 GBG93077.1 - 0.82 7.8 15.9 1.1 7.4 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG93077.1 - 1.1 8.6 16.6 1.4 8.2 16.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG93077.1 - 1.4 7.1 14.1 1.9 6.7 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0242 PF06785.11 GBG93077.1 - 3.2 7.8 5.3 6.4 6.8 5.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 GBG93078.1 - 0.11 12.6 0.3 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 GBG93082.1 - 6.1 7.4 25.2 0.61 10.6 1.7 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region RT_RNaseH_2 PF17919.1 GBG93083.1 - 1.1e-32 112.1 0.2 3.2e-32 110.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93083.1 - 9.1e-29 100.6 0.1 1.5e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG93083.1 - 1.4e-27 96.0 0.0 4e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93083.1 - 6.1e-15 55.1 0.4 1.3e-14 54.0 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG93083.1 - 1.8e-11 44.3 0.0 1.6e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 GBG93083.1 - 1.2e-07 31.6 0.0 2.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG93083.1 - 0.022 15.4 0.0 0.052 14.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GBG93083.1 - 0.028 15.0 0.0 0.073 13.6 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Snapin_Pallidin PF14712.6 GBG93083.1 - 0.15 12.5 0.1 0.15 12.5 0.1 3.0 2 0 0 2 2 2 0 Snapin/Pallidin CR6_interact PF10147.9 GBG93083.1 - 0.43 10.3 5.2 0.91 9.2 5.2 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 eIF3_subunit PF08597.10 GBG93083.1 - 0.45 10.4 4.5 0.79 9.6 4.5 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RVT_1 PF00078.27 GBG93085.1 - 1.1e-26 93.8 0.1 1.5e-26 93.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93085.1 - 2.7e-25 88.3 0.0 1.3e-24 86.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93085.1 - 5e-22 78.2 0.0 2e-21 76.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 GBG93085.1 - 1.3e-05 25.0 0.0 3.7e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG93085.1 - 2e-05 25.1 0.0 5.6e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93085.1 - 4.4e-05 24.0 0.0 0.00012 22.6 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG93085.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG93086.1 - 0.03 14.6 0.3 0.03 14.6 0.3 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Nop14 PF04147.12 GBG93087.1 - 0.07 11.4 7.8 0.069 11.4 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG93087.1 - 0.33 10.3 8.5 0.35 10.2 8.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GBG93087.1 - 1.4 7.2 8.1 1.6 6.9 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG93088.1 - 1.4 7.1 11.4 1.7 6.8 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG93088.1 - 2 6.6 9.1 2.5 6.3 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 GBG93088.1 - 3.1 8.1 15.6 0.52 10.6 11.8 1.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated BTB PF00651.31 GBG93089.1 - 2.8e-13 50.0 0.0 7.1e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 GBG93089.1 - 0.023 14.8 0.0 0.88 9.7 0.0 2.6 3 0 0 3 3 3 0 SPRY domain TIM PF00121.18 GBG93090.1 - 8e-18 64.7 0.0 1.3e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Triosephosphate isomerase HSP70 PF00012.20 GBG93090.1 - 9.8e-07 27.3 0.0 1.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein HCV_NS5a PF01506.19 GBG93090.1 - 0.14 12.1 0.4 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor Myb_DNA-bind_4 PF13837.6 GBG93091.1 - 0.00089 19.6 0.3 0.0022 18.3 0.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-RVT PF13966.6 GBG93091.1 - 0.0036 18.0 1.8 0.0036 18.0 1.8 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase HSP70 PF00012.20 GBG93094.1 - 2.3e-147 491.8 0.0 2.9e-147 491.4 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GBG93094.1 - 8.3e-08 31.4 0.0 1.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GBG93094.1 - 0.0041 16.9 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 GBG93094.1 - 0.0069 15.4 0.1 0.13 11.2 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain DUF3391 PF11871.8 GBG93095.1 - 4.7 7.8 15.6 0.19 12.2 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) RVT_1 PF00078.27 GBG93096.1 - 3.1e-30 105.3 0.1 6.3e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93096.1 - 1.8e-23 82.5 0.0 4.5e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93096.1 - 1.5e-19 70.3 0.0 3.8e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG93096.1 - 1.2e-08 35.4 0.0 2.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG93096.1 - 3.7e-08 33.2 0.0 7.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG93096.1 - 2.1e-06 28.2 0.0 5.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 GBG93096.1 - 0.0019 18.5 0.1 0.058 13.7 0.0 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease PF09668.10 GBG93096.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease WTX PF09422.10 GBG93096.1 - 0.15 11.1 0.8 0.25 10.4 0.8 1.2 1 0 0 1 1 1 0 WTX protein FAM76 PF16046.5 GBG93096.1 - 0.16 11.3 4.0 0.27 10.6 4.0 1.2 1 0 0 1 1 1 0 FAM76 protein Baculo_PEP_C PF04513.12 GBG93096.1 - 0.45 10.5 4.6 0.99 9.4 4.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RT_RNaseH PF17917.1 GBG93097.1 - 2.4e-26 92.0 0.5 6e-26 90.8 0.5 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93097.1 - 2.3e-18 66.0 0.0 5.4e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93097.1 - 1.1e-17 63.8 0.0 2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain IHABP4_N PF16174.5 GBG93097.1 - 2 9.0 6.7 4.6 7.8 6.7 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RT_RNaseH PF17917.1 GBG93098.1 - 9.1e-17 61.3 0.1 1.8e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93098.1 - 1.1e-15 57.4 0.2 6.3e-15 55.0 0.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG93098.1 - 6.2e-14 52.2 0.0 1.3e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 GBG93098.1 - 1.1e-11 44.6 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 GBG93098.1 - 0.00079 19.6 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Arch_fla_DE PF04659.13 GBG93098.1 - 0.02 14.7 0.2 4.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Archaeal flagella protein rve_3 PF13683.6 GBG93098.1 - 0.089 12.6 0.0 0.44 10.4 0.0 2.3 1 0 0 1 1 1 0 Integrase core domain DUF2950 PF11453.8 GBG93099.1 - 0.36 10.0 10.3 0.46 9.6 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) DUF3138 PF11336.8 GBG93099.1 - 0.42 9.2 2.9 0.72 8.4 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TssO PF17561.2 GBG93099.1 - 1.1 9.4 10.8 0.13 12.4 6.6 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssO REV PF00424.18 GBG93099.1 - 5.2 7.2 8.3 0.78 9.8 0.5 2.6 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF4361 PF14274.6 GBG93100.1 - 0.066 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) NRBF2 PF08961.10 GBG93100.1 - 0.1 12.2 4.2 0.15 11.6 4.2 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DivIC PF04977.15 GBG93100.1 - 0.21 11.4 6.4 0.16 11.8 4.6 1.8 1 1 0 1 1 1 0 Septum formation initiator CDC45 PF02724.14 GBG93101.1 - 0.2 9.9 7.4 0.25 9.6 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG93101.1 - 0.24 9.6 5.6 0.25 9.5 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG93101.1 - 0.47 9.8 7.9 0.54 9.6 7.9 1.1 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 GBG93102.1 - 4.1e-30 105.0 0.0 7.9e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG93102.1 - 2.5e-07 30.6 0.0 6.9e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG93102.1 - 7.9e-07 29.6 0.0 2.6e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93102.1 - 5.3e-05 23.7 0.0 0.00018 22.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG93102.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG93102.1 - 0.85 9.9 7.4 0.38 11.0 1.7 3.4 3 1 0 3 3 3 0 Retrotransposon gag protein DUF4360 PF14273.6 GBG93103.1 - 8.4e-38 130.0 0.2 9.7e-38 129.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Peptidase_S21 PF00716.17 GBG93105.1 - 0.12 12.0 0.3 0.17 11.5 0.3 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) RT_RNaseH_2 PF17919.1 GBG93107.1 - 6.4e-28 96.7 0.0 1e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93107.1 - 1.7e-24 86.1 0.0 2.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Cwf_Cwc_15 PF04889.12 GBG93107.1 - 0.28 10.9 6.6 0.47 10.2 6.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GBG93107.1 - 0.94 7.7 6.4 1.4 7.1 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GBG93107.1 - 2.2 6.4 11.7 2.9 6.0 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG93108.1 - 4.2e-28 98.4 0.1 7e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-rbx1 PF12678.7 GBG93108.1 - 4.8e-11 42.8 6.1 1.2e-10 41.5 6.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GBG93108.1 - 2.7e-09 37.2 6.3 6.7e-09 36.0 6.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 GBG93108.1 - 3.1e-09 36.7 0.7 7.9e-09 35.5 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Asp_protease_2 PF13650.6 GBG93108.1 - 4.6e-08 33.6 0.1 4.7e-07 30.4 0.0 2.8 3 0 0 3 3 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93108.1 - 1.3e-07 32.1 0.0 6.8e-07 29.8 0.0 2.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-RING_UBOX PF13445.6 GBG93108.1 - 6.4e-07 29.3 1.5 5.9e-06 26.2 0.3 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GBG93108.1 - 7.7e-07 28.9 4.7 1.8e-06 27.7 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WWE PF02825.20 GBG93108.1 - 1.7e-06 28.5 4.0 4.5e-06 27.2 0.5 2.8 2 0 0 2 2 2 1 WWE domain RVP_2 PF08284.11 GBG93108.1 - 9.4e-06 25.4 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG93108.1 - 1.8e-05 24.5 0.0 3.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-RING_5 PF14634.6 GBG93108.1 - 0.00039 20.3 5.0 0.00082 19.3 5.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GBG93108.1 - 0.0018 18.0 11.1 0.005 16.6 11.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_16 PF17034.5 GBG93108.1 - 0.0047 17.1 2.0 0.21 11.8 1.1 2.7 2 0 0 2 2 2 1 Zinc-ribbon like family FANCL_C PF11793.8 GBG93108.1 - 0.0074 16.4 3.9 0.022 14.9 3.8 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GBG93108.1 - 0.031 13.9 6.1 0.082 12.5 4.6 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GBG93108.1 - 0.52 10.5 5.8 1.3 9.2 5.8 1.7 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 GBG93108.1 - 0.57 10.1 12.2 0.035 14.0 6.1 2.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GBG93108.1 - 0.8 9.6 14.4 0.0089 15.9 5.8 2.3 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GBG93108.1 - 0.92 9.3 13.9 0.17 11.7 8.3 2.5 2 1 0 2 2 2 0 RING-like zinc finger DUF4187 PF13821.6 GBG93108.1 - 1.2 9.0 5.2 0.45 10.3 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf-Nse PF11789.8 GBG93108.1 - 2 8.3 3.7 5.2 7.0 3.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 GBG93108.1 - 2.8 8.3 6.5 7.8 6.9 6.5 1.7 1 0 0 1 1 1 0 RING-like domain DUF659 PF04937.15 GBG93109.1 - 4.8e-21 75.2 0.1 1.6e-20 73.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG93109.1 - 1.7e-10 40.6 0.1 3.8e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Caldesmon PF02029.15 GBG93109.1 - 0.0025 16.7 28.5 0.0049 15.7 28.5 1.5 1 0 0 1 1 1 1 Caldesmon BUD22 PF09073.10 GBG93109.1 - 1.1 8.6 24.5 2.3 7.5 24.5 1.5 1 0 0 1 1 1 0 BUD22 zf-CCHC PF00098.23 GBG93110.1 - 1.5e-06 28.0 0.5 2.9e-06 27.1 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG93110.1 - 0.072 12.9 0.6 0.13 12.1 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle UPF0242 PF06785.11 GBG93110.1 - 0.093 12.8 12.6 0.11 12.6 12.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-CCHC_4 PF14392.6 GBG93110.1 - 0.12 12.1 0.1 0.37 10.6 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle PSII PF00421.19 GBG93110.1 - 0.33 9.6 0.5 0.38 9.4 0.5 1.0 1 0 0 1 1 1 0 Photosystem II protein Presenilin PF01080.17 GBG93110.1 - 4.7 5.9 8.3 5.4 5.7 8.3 1.1 1 0 0 1 1 1 0 Presenilin Sugar_tr PF00083.24 GBG93110.1 - 5 5.9 4.3 6 5.6 4.3 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter ALMT PF11744.8 GBG93110.1 - 8.2 5.1 9.7 10 4.9 9.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MDM10 PF12519.8 GBG93110.1 - 9.8 4.9 8.3 11 4.7 8.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Amino_oxidase PF01593.24 GBG93113.1 - 1.1e-18 67.7 0.0 1.3e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GBG93113.1 - 1.5e-16 60.4 0.0 7.4e-16 58.1 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GBG93113.1 - 4.5e-05 23.2 0.0 6.6e-05 22.6 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GBG93113.1 - 5.1e-05 22.5 0.1 6.6e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GBG93113.1 - 0.00038 19.8 0.0 0.00051 19.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GBG93113.1 - 0.001 18.3 0.1 0.0014 18.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GBG93113.1 - 0.0011 17.8 0.2 0.0014 17.4 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 GBG93113.1 - 0.0042 17.6 0.1 0.0063 17.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.11 GBG93113.1 - 0.0069 16.0 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) Pyr_redox_3 PF13738.6 GBG93113.1 - 0.044 13.0 0.3 0.061 12.6 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GBG93113.1 - 0.12 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GBG93113.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain RVT_1 PF00078.27 GBG93114.1 - 2.5e-25 89.3 0.1 1.4e-24 86.9 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG93114.1 - 1.2e-07 31.6 0.0 3.4e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG93114.1 - 2.6e-06 28.0 0.0 8.5e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93114.1 - 0.0007 20.1 0.0 0.0048 17.4 0.0 2.5 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease TolA_bind_tri PF16331.5 GBG93114.1 - 0.041 14.0 5.4 0.12 12.5 5.4 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation Retrotrans_gag PF03732.17 GBG93114.1 - 0.043 14.1 0.0 0.24 11.7 0.0 2.3 1 0 0 1 1 1 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 GBG93116.1 - 0.0053 17.0 0.6 0.17 12.2 0.0 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein SlyX PF04102.12 GBG93116.1 - 0.021 15.4 3.2 0.021 15.4 3.2 2.4 2 0 0 2 2 2 0 SlyX DASH_Spc34 PF08657.10 GBG93116.1 - 0.2 11.4 3.1 0.28 11.0 3.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF16 PF01519.16 GBG93116.1 - 3.7 8.1 7.5 8.6 6.9 7.5 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 ADIP PF11559.8 GBG93116.1 - 4 7.5 17.0 0.075 13.1 7.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding RT_RNaseH_2 PF17919.1 GBG93117.1 - 4.7e-23 81.1 0.1 1.6e-22 79.4 0.0 1.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93117.1 - 1.3e-12 47.7 0.7 4.1e-07 29.7 0.1 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG93117.1 - 2e-12 47.3 0.0 5.8e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase APG17 PF04108.12 GBG93117.1 - 0.062 12.4 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 gag-asp_proteas PF13975.6 GBG93118.1 - 5.9e-07 30.0 0.1 1.3e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG93118.1 - 8e-05 22.4 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG93118.1 - 0.00044 20.8 0.1 0.0011 19.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG93118.1 - 0.019 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease SnoaL PF07366.12 GBG93118.1 - 0.027 14.3 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Myb_DNA-bind_4 PF13837.6 GBG93120.1 - 2.2e-06 27.9 2.5 1.6e-05 25.2 0.5 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF659 PF04937.15 GBG93121.1 - 6.1e-11 42.4 0.0 1.4e-10 41.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) DDE_Tnp_4 PF13359.6 GBG93121.1 - 1.4e-10 41.1 0.0 3.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG93121.1 - 0.002 17.8 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Alanine_zipper PF11839.8 GBG93123.1 - 0.04 14.3 17.9 0.11 12.8 17.9 1.7 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein HI0933_like PF03486.14 GBG93124.1 - 6.6e-33 114.0 0.0 8.6e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 GBG93124.1 - 0.0005 19.3 0.8 0.0011 18.1 0.8 1.6 1 1 0 1 1 1 1 FAD binding domain Astro_capsid_p PF12226.8 GBG93125.1 - 0.013 14.7 9.6 0.018 14.2 9.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 GBG93125.1 - 0.079 11.2 14.7 0.086 11.0 14.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GBG93125.1 - 0.079 12.3 19.2 0.11 11.8 19.2 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GBG93125.1 - 1.2 8.5 18.0 1.5 8.2 18.0 1.1 1 0 0 1 1 1 0 SDA1 ORC_WH_C PF18137.1 GBG93125.1 - 1.6 8.8 7.4 2.8 8.0 7.4 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DNA_pol_phi PF04931.13 GBG93125.1 - 3.1 5.8 24.3 4.3 5.3 24.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GBG93125.1 - 5.3 5.2 14.7 6.8 4.9 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Memo PF01875.17 GBG93126.1 - 5.1e-83 278.3 0.0 5.9e-83 278.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Peptidase_M50 PF02163.22 GBG93129.1 - 0.019 14.2 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M50 DUF1639 PF07797.14 GBG93129.1 - 0.081 12.9 0.1 0.34 10.9 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) RNA_pol_Rpb2_6 PF00562.28 GBG93130.1 - 4.2e-90 302.6 0.0 5.2e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_5 PF04567.17 GBG93130.1 - 4.1e-20 72.1 0.2 1.1e-19 70.8 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 GBG93130.1 - 1.5e-18 66.8 0.0 2.6e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 Integrase_H2C2 PF17921.1 GBG93131.1 - 2.8e-14 52.9 0.1 6.3e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG93131.1 - 0.0079 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG93131.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 GBG93132.1 - 5.6e-05 22.8 0.0 9.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93132.1 - 0.0003 20.8 0.0 0.00059 19.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93132.1 - 0.013 15.8 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase CDC45 PF02724.14 GBG93133.1 - 0.71 8.1 12.5 0.92 7.7 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GBG93133.1 - 0.75 9.3 7.5 0.95 9.0 7.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 GBG93133.1 - 1.1 8.6 21.2 1.3 8.4 21.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GBG93133.1 - 1.2 7.2 20.1 1.4 7.1 20.1 1.0 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 GBG93133.1 - 2.1 7.4 8.5 2.4 7.2 8.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 GBG93133.1 - 5.3 6.3 21.0 8.5 5.6 21.0 1.3 1 0 0 1 1 1 0 BUD22 Ribosomal_L27 PF01016.19 GBG93134.1 - 4e-37 126.1 3.6 6e-37 125.5 3.6 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein FAD-oxidase_C PF02913.19 GBG93135.1 - 1.2e-26 93.8 0.1 3.7e-26 92.3 0.1 1.9 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain DUF659 PF04937.15 GBG93135.1 - 1.3e-25 90.0 0.0 3.3e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG93135.1 - 2.5e-08 33.6 1.0 7.1e-08 32.1 1.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCHC PF00098.23 GBG93135.1 - 0.0011 19.0 2.7 0.0032 17.5 2.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG93135.1 - 0.043 13.7 3.6 0.12 12.2 3.6 1.8 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GBG93136.1 - 3.1e-21 75.2 0.6 2.5e-19 69.1 0.1 2.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG93136.1 - 2e-09 37.6 0.0 5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG93136.1 - 0.003 17.8 3.1 1 9.7 0.4 3.1 2 0 0 2 2 2 2 Retrotransposon gag protein zf-H2C2 PF09337.10 GBG93136.1 - 0.026 14.7 0.0 0.084 13.1 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF4373 PF14297.6 GBG93136.1 - 0.16 12.8 0.7 0.42 11.4 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) DUF4852 PF16144.5 GBG93136.1 - 0.44 10.7 1.9 1.3 9.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4852) RT_RNaseH_2 PF17919.1 GBG93137.1 - 1.2e-23 83.0 0.0 5.2e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93137.1 - 3.4e-12 46.6 0.0 1.6e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93137.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_lysozyme PF00959.19 GBG93137.1 - 0.11 13.0 0.2 0.85 10.1 0.0 2.4 2 0 0 2 2 2 0 Phage lysozyme CENP-Q PF13094.6 GBG93138.1 - 0.00099 19.3 4.5 0.0017 18.6 4.5 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Myb_DNA-bind_4 PF13837.6 GBG93140.1 - 3.9e-09 36.8 3.3 6.2e-09 36.1 3.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain LapA_dom PF06305.11 GBG93140.1 - 0.0015 18.3 0.8 0.0025 17.6 0.8 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain MADF_DNA_bdg PF10545.9 GBG93140.1 - 0.0033 17.7 1.8 0.0071 16.6 1.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like MAP17 PF15807.5 GBG93140.1 - 0.012 15.9 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF3413 PF11893.8 GBG93140.1 - 0.031 13.4 0.3 0.043 13.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Myb_DNA-bind_5 PF13873.6 GBG93140.1 - 0.076 13.1 0.8 0.15 12.2 0.8 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG93143.1 - 6.9e-24 83.8 0.0 1.1e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93143.1 - 1.3e-22 80.0 0.0 2.2e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93143.1 - 3.2e-08 33.3 0.3 5.2e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 GBG93144.1 - 0.0023 16.3 6.4 0.0026 16.1 6.4 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.9 GBG93144.1 - 0.0024 17.1 14.3 0.0028 16.9 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) BSP_II PF05432.11 GBG93144.1 - 0.0028 17.4 22.7 0.0035 17.1 22.7 1.0 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) NUT PF12881.7 GBG93144.1 - 0.0044 15.5 1.3 0.0053 15.3 1.3 1.0 1 0 0 1 1 1 1 NUT protein CDC45 PF02724.14 GBG93144.1 - 0.029 12.7 7.2 0.033 12.5 7.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop25 PF09805.9 GBG93144.1 - 0.043 14.3 7.7 0.055 13.9 7.7 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) RRN3 PF05327.11 GBG93144.1 - 0.073 11.6 4.4 0.071 11.7 4.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Macoilin PF09726.9 GBG93144.1 - 0.14 10.7 6.2 0.15 10.6 6.2 1.1 1 0 0 1 1 1 0 Macoilin family SDA1 PF05285.12 GBG93144.1 - 0.15 11.5 13.8 0.18 11.2 13.8 1.1 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 GBG93144.1 - 0.17 11.0 3.6 0.17 11.0 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mucin PF01456.17 GBG93144.1 - 0.71 9.9 35.1 0.89 9.5 35.1 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein Striatin PF08232.12 GBG93144.1 - 1 9.9 5.3 1.5 9.4 5.3 1.4 1 1 0 1 1 1 0 Striatin family Menin PF05053.13 GBG93144.1 - 2.9 6.2 7.1 3.7 5.8 7.1 1.3 1 0 0 1 1 1 0 Menin CobT PF06213.12 GBG93144.1 - 3.4 7.0 10.4 4.2 6.7 10.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 GBG93144.1 - 3.5 6.3 8.1 3.9 6.2 8.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF659 PF04937.15 GBG93145.1 - 1.3e-07 31.6 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Topo_Zn_Ribbon PF08272.11 GBG93146.1 - 0.019 14.6 0.3 0.092 12.4 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG93146.1 - 0.025 14.7 1.9 0.041 14.0 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 GBG93147.1 - 5e-12 45.8 0.0 4.2e-09 36.3 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Ole-e-6 PF09253.10 GBG93148.1 - 0.077 13.0 4.2 4.1 7.4 0.2 2.2 2 0 0 2 2 2 0 Pollen allergen ole e 6 zf-CCHC PF00098.23 GBG93149.1 - 6.6e-07 29.1 4.1 1e-06 28.5 4.1 1.3 1 0 0 1 1 1 1 Zinc knuckle RF-1 PF00472.20 GBG93151.1 - 1.1e-21 77.0 4.2 1.8e-21 76.2 4.2 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 GBG93151.1 - 0.0026 18.2 0.7 0.0041 17.6 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF460 PF04312.13 GBG93151.1 - 0.13 12.0 1.7 0.21 11.3 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Apolipoprotein PF01442.18 GBG93153.1 - 0.00021 21.2 9.7 0.00033 20.6 9.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GBG93153.1 - 0.029 14.9 11.1 0.42 11.2 5.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GBG93153.1 - 0.086 13.4 11.8 50 4.5 11.8 2.3 1 1 0 1 1 1 0 YtxH-like protein Mitofilin PF09731.9 GBG93153.1 - 0.15 10.9 10.8 0.16 10.8 10.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ax_dynein_light PF10211.9 GBG93153.1 - 0.38 10.7 7.3 0.4 10.6 7.3 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4230 PF14014.6 GBG93153.1 - 0.66 10.2 4.7 0.77 10.0 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) LEA_1 PF03760.15 GBG93153.1 - 0.82 10.4 26.4 2.8 8.6 20.7 2.5 2 1 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 DUF3584 PF12128.8 GBG93153.1 - 3.1 5.2 9.7 3.5 5.0 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HisKA_3 PF07730.13 GBG93153.1 - 3.5 8.2 7.6 16 6.1 2.2 2.7 1 1 2 3 3 3 0 Histidine kinase Mito_carr PF00153.27 GBG93154.1 - 5.5e-38 128.8 0.2 5.8e-13 48.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GBG93154.1 - 3.2e-12 46.7 0.1 2e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GBG93154.1 - 3.7e-07 29.2 0.0 0.069 12.7 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GBG93154.1 - 5.4e-06 25.9 0.0 0.17 11.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GBG93154.1 - 0.0025 17.6 0.2 4 7.4 0.2 2.9 2 1 0 2 2 2 2 EF-hand domain pair RT_RNaseH_2 PF17919.1 GBG93156.1 - 2.3e-23 82.1 0.0 4.3e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93156.1 - 1.8e-20 73.2 0.0 3.6e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG93158.1 - 5.6e-09 36.4 0.0 1.2e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93158.1 - 2e-08 34.8 0.0 4.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG93158.1 - 0.00019 21.2 1.3 0.00037 20.3 1.3 1.4 1 0 0 1 1 1 1 Aspartyl protease eIF3g PF12353.8 GBG93158.1 - 0.0036 17.7 0.3 0.012 16.0 0.3 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RVP PF00077.20 GBG93158.1 - 0.019 15.3 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Cwf_Cwc_15 PF04889.12 GBG93158.1 - 7.2 6.3 13.4 28 4.3 13.4 2.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myb_DNA-bind_4 PF13837.6 GBG93160.1 - 1.7e-05 25.1 1.7 2.3e-05 24.7 1.7 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG93160.1 - 0.00073 19.6 0.3 0.0011 18.9 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 GBG93160.1 - 0.0023 18.1 0.1 0.0048 17.1 0.1 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain RT_RNaseH_2 PF17919.1 GBG93161.1 - 1.9e-17 63.1 0.0 4.1e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93161.1 - 7.5e-07 29.4 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG93161.1 - 9.4e-06 25.5 3.2 1.6e-05 24.8 3.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG93161.1 - 0.019 14.8 4.1 0.031 14.1 4.1 1.3 1 0 0 1 1 1 0 Zinc knuckle Pkinase_Tyr PF07714.17 GBG93162.1 - 1.3e-37 129.5 0.0 3.3e-37 128.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GBG93162.1 - 2.8e-34 118.7 0.0 6e-34 117.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 GBG93162.1 - 5e-34 116.3 0.0 8.5e-34 115.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93162.1 - 6.1e-29 100.4 0.2 1.1e-28 99.6 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase APH PF01636.23 GBG93162.1 - 0.011 15.6 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Creatinase_N PF01321.18 GBG93162.1 - 0.11 13.2 0.0 27 5.4 0.0 2.6 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain Pkinase_fungal PF17667.1 GBG93162.1 - 0.14 10.9 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4699 PF15770.5 GBG93163.1 - 8 6.1 7.7 12 5.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) RVT_1 PF00078.27 GBG93164.1 - 1.3e-27 96.7 0.0 2.1e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93164.1 - 2.8e-15 56.2 0.0 6.4e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93164.1 - 5.1e-15 55.3 1.7 1.4e-14 53.9 0.0 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 GBG93164.1 - 1.6e-11 44.5 0.0 4.8e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG93164.1 - 0.00031 20.9 0.0 0.00077 19.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 GBG93164.1 - 0.003 17.8 0.0 0.0074 16.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG93164.1 - 0.016 15.8 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Ribosomal_L10 PF00466.20 GBG93166.1 - 2.9e-20 72.2 2.0 4.5e-20 71.7 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 GBG93166.1 - 5.6e-20 71.1 0.3 1.4e-19 69.9 0.1 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 GBG93166.1 - 7.5e-20 71.3 7.1 1.9e-19 70.0 7.1 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 GBG93166.1 - 0.35 9.3 3.3 0.52 8.7 3.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein VID27_N PF17748.1 GBG93166.1 - 0.63 9.9 0.0 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 VID27 N-terminal region RT_RNaseH PF17917.1 GBG93167.1 - 1.3e-20 73.7 0.0 2.8e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93167.1 - 1.4e-19 70.0 0.0 2.9e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93167.1 - 1e-14 54.4 0.2 2.2e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG93167.1 - 1.7e-14 54.0 0.0 4.9e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain SlyX PF04102.12 GBG93167.1 - 0.015 15.9 2.6 0.6 10.8 0.0 4.1 3 0 0 3 3 3 0 SlyX zf-H2C2 PF09337.10 GBG93167.1 - 0.092 13.0 0.4 0.27 11.5 0.2 2.0 2 0 0 2 2 2 0 H2C2 zinc finger zf-CCHC PF00098.23 GBG93167.1 - 1.1 9.4 11.6 5.5 7.2 4.5 2.9 2 0 0 2 2 2 0 Zinc knuckle DUF1840 PF08895.11 GBG93168.1 - 0.07 13.5 20.4 0.019 15.3 3.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) zf-CCHC PF00098.23 GBG93168.1 - 0.16 12.1 2.1 0.33 11.1 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DAG_kinase_N PF14513.6 GBG93168.1 - 1.8 8.8 9.3 0.61 10.3 0.6 2.6 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus PP_M1 PF03012.14 GBG93169.1 - 0.23 11.0 2.5 0.39 10.2 2.5 1.4 1 0 0 1 1 1 0 Phosphoprotein FAM176 PF14851.6 GBG93171.1 - 0.011 15.4 4.8 0.017 14.8 4.8 1.3 1 0 0 1 1 1 0 FAM176 family CobT PF06213.12 GBG93171.1 - 0.018 14.5 9.0 0.019 14.4 9.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 GBG93171.1 - 0.021 14.3 10.3 0.022 14.2 10.3 1.0 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 GBG93171.1 - 0.029 14.3 4.5 0.032 14.2 4.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CENP-B_dimeris PF09026.10 GBG93171.1 - 0.056 13.8 10.2 0.079 13.4 10.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cnd2 PF05786.14 GBG93171.1 - 0.058 12.1 4.8 0.062 12.0 4.8 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 PTPRCAP PF15713.5 GBG93171.1 - 0.066 13.5 11.3 0.079 13.2 11.3 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated YL1 PF05764.13 GBG93171.1 - 0.083 13.0 13.6 0.094 12.8 13.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DDHD PF02862.17 GBG93171.1 - 0.089 12.9 1.2 0.1 12.7 1.2 1.1 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.6 GBG93171.1 - 0.11 12.7 2.1 0.12 12.6 2.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 GBG93171.1 - 0.12 10.6 11.8 0.12 10.5 11.8 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GBG93171.1 - 0.23 9.7 10.3 0.24 9.7 10.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 GBG93171.1 - 0.34 10.7 7.1 0.41 10.4 7.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.13 GBG93171.1 - 0.56 9.2 13.6 0.74 8.8 13.6 1.1 1 0 0 1 1 1 0 Paf1 Connexin PF00029.19 GBG93171.1 - 0.61 9.8 2.1 0.7 9.6 2.1 1.1 1 0 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 GBG93171.1 - 0.67 8.0 16.0 0.7 7.9 16.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4746 PF15928.5 GBG93171.1 - 0.72 9.2 8.4 1 8.7 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GEN1_C PF18380.1 GBG93171.1 - 0.92 10.4 7.5 1.3 10.0 7.5 1.2 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain PBP1_TM PF14812.6 GBG93171.1 - 0.97 9.8 7.0 1.7 9.1 7.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 GBG93171.1 - 1 9.4 9.6 1.3 9.0 9.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 GBG93171.1 - 1.1 7.8 8.5 1 7.8 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4637 PF15470.6 GBG93171.1 - 1.1 8.9 11.6 1.4 8.6 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TFIIF_alpha PF05793.12 GBG93171.1 - 1.2 7.7 15.6 1.2 7.6 15.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.12 GBG93171.1 - 1.5 8.1 16.2 1.8 7.8 16.2 1.1 1 0 0 1 1 1 0 NOA36 protein HSP90 PF00183.18 GBG93171.1 - 1.8 7.4 10.5 2.2 7.1 10.5 1.0 1 0 0 1 1 1 0 Hsp90 protein PI3K_1B_p101 PF10486.9 GBG93171.1 - 1.8 6.2 4.2 1.9 6.2 4.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop53 PF07767.11 GBG93171.1 - 2.3 7.5 12.6 2.8 7.2 12.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sigma70_ner PF04546.13 GBG93171.1 - 2.9 7.7 13.9 1 9.2 11.5 1.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Pes-10 PF07149.11 GBG93171.1 - 3.3 6.7 11.1 3.4 6.6 11.1 1.1 1 0 0 1 1 1 0 Pes-10 DUF2457 PF10446.9 GBG93171.1 - 4.8 6.2 19.5 5.6 6.0 19.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF659 PF04937.15 GBG93174.1 - 8.4e-08 32.2 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RVT_1 PF00078.27 GBG93176.1 - 1.4e-31 109.8 0.1 1.9e-31 109.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF898 PF05987.13 GBG93176.1 - 0.43 9.6 24.2 0.25 10.4 4.7 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) Chromo PF00385.24 GBG93177.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF898 PF05987.13 GBG93178.1 - 0.018 14.1 62.8 0.63 9.0 8.4 5.0 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF898) EI24 PF07264.11 GBG93178.1 - 0.54 10.5 56.3 1.1 9.4 14.6 3.4 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) DHHC PF01529.20 GBG93178.1 - 6.9 6.8 36.6 2.5 8.2 3.4 5.1 3 2 2 6 6 6 0 DHHC palmitoyltransferase Amnionless PF14828.6 GBG93179.1 - 0.073 11.9 4.2 0.09 11.6 4.2 1.2 1 0 0 1 1 1 0 Amnionless DUF1700 PF08006.11 GBG93179.1 - 0.078 12.5 6.3 0.096 12.2 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) PRA1 PF03208.19 GBG93179.1 - 0.097 12.3 9.5 0.1 12.2 9.5 1.1 1 0 0 1 1 1 0 PRA1 family protein Ac81 PF05820.11 GBG93179.1 - 0.16 11.6 2.6 0.19 11.3 2.6 1.1 1 0 0 1 1 1 0 Baculoviridae AC81 CBP_BcsG PF11658.8 GBG93179.1 - 0.25 9.7 3.0 0.23 9.8 3.0 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG FA_desaturase PF00487.24 GBG93179.1 - 0.58 9.9 6.4 0.64 9.8 6.4 1.2 1 1 0 1 1 1 0 Fatty acid desaturase DUF3742 PF12553.8 GBG93179.1 - 1.2 9.2 8.7 1.5 9.0 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) DUF4231 PF14015.6 GBG93179.1 - 3.4 8.2 5.3 4.6 7.8 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) HSP20 PF00011.21 GBG93180.1 - 3e-29 101.2 0.1 4.4e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG93180.1 - 2.5e-09 36.5 0.4 5.1e-09 35.5 0.4 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 GBG93180.1 - 0.064 13.4 0.0 2 8.6 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal RT_RNaseH PF17917.1 GBG93181.1 - 1.5e-08 34.9 0.0 2.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93181.1 - 1.7e-05 24.8 0.1 8.6e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG93181.1 - 2.2e-05 24.9 0.4 6.4e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93181.1 - 0.00055 20.5 0.0 0.0017 18.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG93181.1 - 0.0067 16.2 0.6 0.013 15.3 0.6 1.4 1 0 0 1 1 1 1 Aspartyl protease HSP20 PF00011.21 GBG93182.1 - 3e-29 101.2 0.1 4.4e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG93182.1 - 2.5e-09 36.5 0.4 5.1e-09 35.5 0.4 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 GBG93182.1 - 0.064 13.4 0.0 2 8.6 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal DUF659 PF04937.15 GBG93183.1 - 1.7e-25 89.7 2.0 2.7e-25 89.0 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG93183.1 - 0.00078 19.2 0.1 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 GBG93185.1 - 0.00015 22.3 0.1 0.0004 20.9 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93185.1 - 0.0033 18.0 0.1 0.012 16.2 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG93185.1 - 0.013 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG93185.1 - 0.041 13.7 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 GBG93186.1 - 4.5e-25 88.5 0.0 7.7e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GBG93186.1 - 1.3e-09 38.0 0.1 3e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glycos_transf_1 PF00534.20 GBG93188.1 - 2.4e-16 59.7 0.0 3.8e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GBG93188.1 - 5.1e-11 43.1 0.0 9.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 RT_RNaseH PF17917.1 GBG93191.1 - 3.4e-24 85.2 0.0 6.3e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93191.1 - 1.1e-23 83.1 0.0 2.3e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93191.1 - 6.2e-10 39.0 0.4 1.7e-09 37.7 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GBG93191.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain CLZ PF16526.5 GBG93192.1 - 0.071 13.5 0.4 0.071 13.5 0.4 3.1 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Retrotrans_gag PF03732.17 GBG93192.1 - 0.2 12.0 3.4 1.7 9.0 0.2 2.5 2 1 0 2 2 2 0 Retrotransposon gag protein STAG PF08514.11 GBG93192.1 - 0.59 10.1 0.1 0.59 10.1 0.1 2.4 2 1 0 2 2 2 0 STAG domain WDCP PF15390.6 GBG93192.1 - 0.68 8.3 3.8 0.84 7.9 3.8 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Siah-Interact_N PF09032.11 GBG93192.1 - 2.2 8.6 8.6 56 4.1 6.5 3.0 2 1 0 2 2 2 0 Siah interacting protein, N terminal adh_short PF00106.25 GBG93193.1 - 5.6e-29 101.0 0.2 6.9e-14 51.7 0.0 3.8 3 1 1 4 4 4 3 short chain dehydrogenase adh_short_C2 PF13561.6 GBG93193.1 - 3.1e-23 82.6 0.9 2.6e-09 37.0 0.0 3.6 3 1 1 4 4 4 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GBG93193.1 - 0.012 15.5 0.0 0.057 13.3 0.1 1.9 2 0 0 2 2 2 0 KR domain zf-CCHC_3 PF13917.6 GBG93194.1 - 0.058 13.4 0.6 0.1 12.6 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 GBG93194.1 - 0.083 13.2 0.3 0.2 11.9 0.0 1.8 2 1 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_6 PF15288.6 GBG93194.1 - 0.088 12.7 1.3 0.19 11.6 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG93194.1 - 0.55 10.4 3.3 0.84 9.8 3.3 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG93195.1 - 1.7e-17 63.3 0.0 3.9e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93195.1 - 5.8e-08 33.0 0.2 2.2e-07 31.1 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RE_AlwI PF09491.10 GBG93195.1 - 0.084 11.7 2.3 0.1 11.4 2.3 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease PA26 PF04636.13 GBG93195.1 - 0.09 11.7 6.0 0.11 11.4 6.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TssO PF17561.2 GBG93195.1 - 0.092 12.9 6.5 0.045 13.9 3.3 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssO PRTP PF01366.18 GBG93195.1 - 0.28 9.2 4.2 0.32 9.0 4.2 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF3138 PF11336.8 GBG93195.1 - 0.33 9.5 0.7 0.43 9.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) T2SSM PF04612.12 GBG93195.1 - 0.39 10.7 8.4 2.5 8.1 8.1 2.1 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein M Herpes_UL25 PF01499.16 GBG93195.1 - 1.7 7.1 4.4 1.8 7.0 4.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3629 PF12302.8 GBG93195.1 - 2.7 7.4 7.4 4.2 6.7 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DUF5401 PF17380.2 GBG93195.1 - 2.9 5.8 19.6 3.4 5.6 19.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4407 PF14362.6 GBG93195.1 - 3.1 7.1 11.4 4 6.7 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 GBG93197.1 - 0.0087 16.6 3.2 0.0087 16.6 3.2 3.5 3 1 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3006 PF11213.8 GBG93197.1 - 0.13 12.5 1.5 0.31 11.3 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Retrotrans_gag PF03732.17 GBG93197.1 - 6.1 7.2 9.8 2 8.7 0.2 3.4 3 1 0 3 3 3 0 Retrotransposon gag protein KN17_SH3 PF18131.1 GBG93200.1 - 0.0019 18.2 0.2 46 4.2 0.0 5.7 6 0 0 6 6 6 1 KN17 SH3-like C-terminal domain Microvir_J PF04726.13 GBG93202.1 - 9.9 6.2 14.0 6.7 6.8 0.2 3.8 3 1 0 3 3 3 0 Microvirus J protein zf-CCHC PF00098.23 GBG93204.1 - 4e-05 23.5 3.2 9.4e-05 22.3 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG93204.1 - 0.2 11.5 3.8 0.48 10.3 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 GBG93205.1 - 1.4e-25 89.2 0.0 9e-25 86.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93205.1 - 3.2e-20 72.4 0.0 1.3e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93205.1 - 1e-18 67.7 0.1 6.9e-18 65.0 0.1 1.9 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG93205.1 - 0.0077 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease SGL PF08450.12 GBG93206.1 - 0.044 13.4 0.1 4 7.0 0.0 2.8 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region MSA-2c PF12238.8 GBG93206.1 - 6.5 6.7 6.2 9.9 6.1 6.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pkinase PF00069.25 GBG93207.1 - 1.1e-11 44.6 0.3 4.8e-10 39.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GBG93207.1 - 5.5e-10 39.0 0.1 4.6e-08 32.7 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GBG93207.1 - 0.0031 17.5 0.1 0.0075 16.2 0.0 1.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG93207.1 - 0.057 12.2 0.0 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase SURF2 PF05477.11 GBG93208.1 - 0.58 9.8 5.6 0.18 11.5 2.9 1.5 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) RVT_1 PF00078.27 GBG93209.1 - 1.3e-29 103.3 0.1 1.9e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG93209.1 - 4.2e-08 33.7 0.0 8.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93209.1 - 5.8e-08 33.3 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG93209.1 - 8.2e-07 28.9 0.0 2.1e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG93209.1 - 1.1e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease TPT PF03151.16 GBG93210.1 - 2.9e-18 66.2 18.7 3.7e-18 65.9 18.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GBG93210.1 - 7.8e-09 35.2 22.8 9.9e-09 34.8 22.8 1.1 1 0 0 1 1 1 1 UAA transporter family NARG2_C PF10505.9 GBG93211.1 - 2.6e-17 63.1 0.0 8.4e-16 58.1 0.0 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated gene protein 2 C-terminus API5 PF05918.11 GBG93211.1 - 3.7 6.2 4.8 5.6 5.7 4.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RT_RNaseH_2 PF17919.1 GBG93212.1 - 5.1e-24 84.2 0.0 1.3e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93212.1 - 5.1e-21 74.9 0.0 1.5e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DivIC PF04977.15 GBG93212.1 - 0.015 15.0 2.1 0.041 13.6 2.1 1.7 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 GBG93212.1 - 0.027 14.7 1.5 0.059 13.6 1.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GBG93212.1 - 0.063 13.4 2.0 0.14 12.3 2.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 GBG93212.1 - 0.073 13.2 3.6 0.21 11.7 3.6 1.8 1 0 0 1 1 1 0 Basic region leucine zipper CCD48 PF15799.5 GBG93212.1 - 0.14 10.5 4.8 0.19 10.0 4.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF1515 PF07439.11 GBG93212.1 - 0.14 12.2 0.2 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) ZapB PF06005.12 GBG93212.1 - 0.15 12.5 5.0 0.45 11.0 3.9 1.9 1 1 0 1 1 1 0 Cell division protein ZapB DUF4988 PF16378.5 GBG93212.1 - 0.18 11.5 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF386 PF04074.12 GBG93212.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 YhcH/YjgK/YiaL NYD-SP28_assoc PF14775.6 GBG93212.1 - 0.28 11.3 3.4 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain ABC_tran_CTD PF16326.5 GBG93212.1 - 0.6 10.4 7.0 0.25 11.6 1.8 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain GIT_CC PF16559.5 GBG93212.1 - 2.3 8.1 5.7 0.81 9.6 1.9 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor RVT_1 PF00078.27 GBG93213.1 - 6.3e-05 22.6 0.2 0.00042 19.9 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRP21_like_P PF12230.8 GBG93213.1 - 0.082 12.8 0.3 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein FtsJ PF01728.19 GBG93215.1 - 2.6e-18 66.8 0.0 3.9e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 GBG93215.1 - 1.4e-08 34.3 0.1 4.4e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 S4 domain Methyltransf_25 PF13649.6 GBG93215.1 - 0.016 15.9 0.0 0.039 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GBG93215.1 - 0.11 13.2 0.0 0.34 11.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GBG93215.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LRRNT_2 PF08263.12 GBG93216.1 - 0.0017 18.6 4.8 0.0017 18.6 4.8 1.9 2 1 0 2 2 2 1 Leucine rich repeat N-terminal domain FragX_IP PF05994.11 GBG93217.1 - 0.38 8.7 0.0 0.51 8.3 0.0 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family DDE_Tnp_4 PF13359.6 GBG93218.1 - 5.7e-34 117.1 0.0 8.5e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG93218.1 - 2.7e-15 56.5 0.0 4.4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GBG93218.1 - 0.00074 19.2 0.1 1.2 8.7 0.0 2.4 2 1 0 2 2 2 2 Transposase DDE domain AIP3 PF03915.13 GBG93220.1 - 0.11 11.5 8.2 0.17 10.9 8.2 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Phage_GPO PF05929.11 GBG93220.1 - 1.3 8.6 8.1 2.6 7.6 8.1 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ABC_tran_Xtn PF12848.7 GBG93220.1 - 1.5 8.9 11.9 1.4 9.0 0.6 2.6 1 1 1 2 2 2 0 ABC transporter MFAP1 PF06991.11 GBG93220.1 - 1.7 8.4 13.6 2.6 7.8 13.6 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Exonuc_VII_L PF02601.15 GBG93220.1 - 2.1 7.8 10.4 3.2 7.3 10.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SKA2 PF16740.5 GBG93220.1 - 3.8 7.3 13.8 0.42 10.4 7.0 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF2203 PF09969.9 GBG93220.1 - 8 7.2 10.3 0.51 11.1 0.4 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) RT_RNaseH PF17917.1 GBG93223.1 - 2.4e-26 92.1 0.0 3.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93223.1 - 5.3e-26 90.6 0.0 8.2e-26 90.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93223.1 - 6e-14 52.1 0.0 9.2e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG93223.1 - 0.042 13.7 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) DUF3545 PF12065.8 GBG93224.1 - 0.79 9.8 3.6 1.5 8.9 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) Retrotrans_gag PF03732.17 GBG93225.1 - 0.0002 21.6 4.6 0.00073 19.8 0.1 3.5 3 1 0 3 3 3 1 Retrotransposon gag protein Mt_ATP-synt_B PF05405.14 GBG93225.1 - 3.7 7.2 8.7 4.9 6.7 7.5 1.8 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Caudo_TAP PF02413.17 GBG93225.1 - 8.6 6.5 11.9 3.7 7.7 3.4 2.7 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK CDC45 PF02724.14 GBG93226.1 - 0.019 13.3 8.1 0.022 13.1 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4366 PF14283.6 GBG93226.1 - 0.16 12.0 2.4 0.4 10.7 2.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 GBG93226.1 - 0.27 9.9 5.1 0.34 9.6 5.1 1.0 1 0 0 1 1 1 0 Presenilin KH_6 PF15985.5 GBG93227.1 - 2.2e-15 56.7 0.0 4.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 GBG93227.1 - 0.00076 19.4 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Pkinase_Tyr PF07714.17 GBG93229.1 - 1.3e-39 136.1 0.0 5.8e-39 133.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GBG93229.1 - 1.1e-35 123.3 0.0 1.6e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GBG93229.1 - 0.016 15.2 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DarA_N PF18788.1 GBG93229.1 - 0.12 12.4 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Defence against restriction A N-terminal Myb_DNA-bind_4 PF13837.6 GBG93230.1 - 9e-06 26.0 3.6 0.00021 21.6 1.0 2.4 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG93230.1 - 0.069 13.5 1.5 0.26 11.6 0.4 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AA_permease_2 PF13520.6 GBG93231.1 - 4.5e-54 183.9 25.4 4.5e-54 183.9 25.4 2.2 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 GBG93231.1 - 3.1e-43 148.1 24.7 4.6e-43 147.5 24.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GBG93231.1 - 2.5e-20 72.3 4.9 5.8e-20 71.1 2.4 2.8 2 0 0 2 2 2 1 C-terminus of AA_permease Rho_N PF07498.12 GBG93232.1 - 0.0005 19.9 0.2 0.0014 18.5 0.2 1.8 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 GBG93232.1 - 0.0077 16.0 1.6 0.012 15.3 0.1 2.3 2 0 0 2 2 2 1 SAP domain RT_RNaseH_2 PF17919.1 GBG93233.1 - 4e-53 177.6 0.0 1.2e-30 105.5 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93233.1 - 9.8e-44 147.9 0.0 1.9e-21 76.3 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93233.1 - 6.7e-28 97.7 0.0 1.2e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG93233.1 - 3.4e-18 65.5 0.9 6.9e-18 64.5 0.9 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC_3 PF13917.6 GBG93233.1 - 0.0063 16.5 1.0 0.015 15.3 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF898 PF05987.13 GBG93233.1 - 0.12 11.4 18.0 0.14 11.2 10.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) MgtE PF01769.16 GBG93233.1 - 0.99 9.8 21.1 0.33 11.3 9.7 2.4 2 0 0 2 2 2 0 Divalent cation transporter zf-CCHC PF00098.23 GBG93233.1 - 2.3 8.4 4.7 4.6 7.5 4.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 GBG93234.1 - 3.9e-08 33.8 0.0 1.4e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93234.1 - 2.7e-07 31.1 0.0 1.1e-06 29.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG93234.1 - 2.1e-06 27.6 0.0 5.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG93234.1 - 0.00037 20.3 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GBG93234.1 - 0.00079 19.7 0.5 0.002 18.3 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Senescence_reg PF04520.13 GBG93234.1 - 0.15 12.9 4.9 0.16 12.8 2.5 2.2 3 0 0 3 3 3 0 Senescence regulator UPF0565 PF10561.9 GBG93235.1 - 1.4e-14 54.0 0.0 5.9e-13 48.7 0.0 2.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0565 Ccdc124 PF06244.12 GBG93236.1 - 3.9e-37 127.7 5.3 3.9e-37 127.7 5.3 2.6 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF659 PF04937.15 GBG93238.1 - 1.3e-07 31.6 0.1 2.3e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 GBG93238.1 - 3e-05 23.7 0.2 0.00038 20.2 0.2 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Integrase_H2C2 PF17921.1 GBG93239.1 - 1.4e-14 53.9 0.1 3.4e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG93239.1 - 0.00063 20.2 0.0 0.0019 18.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93239.1 - 0.0014 19.3 0.0 0.0033 18.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG93239.1 - 0.0031 17.7 4.9 0.0031 17.7 4.9 2.9 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 zf-H2C2 PF09337.10 GBG93239.1 - 0.088 13.0 1.4 0.2 11.9 0.3 2.2 2 0 0 2 2 2 0 H2C2 zinc finger CENP-N PF05238.13 GBG93239.1 - 3.3 6.9 7.5 5.6 6.2 7.5 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like TPH PF13868.6 GBG93240.1 - 5e-23 81.2 46.5 6.4e-23 80.8 46.5 1.1 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Integrase_H2C2 PF17921.1 GBG93241.1 - 5.8e-15 55.1 0.0 1.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG93241.1 - 2.1e-09 37.6 0.0 5.1e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG93242.1 - 4.8e-05 23.9 0.0 0.00018 22.1 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93242.1 - 0.00039 20.9 0.0 0.00099 19.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG93242.1 - 0.0084 15.9 0.0 0.024 14.4 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG93242.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease SoPB_HTH PF18090.1 GBG93242.1 - 0.071 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Centromere-binding protein HTH domain Senescence_reg PF04520.13 GBG93242.1 - 0.14 13.0 3.5 0.11 13.4 1.3 2.0 2 0 0 2 2 2 0 Senescence regulator KRTAP7 PF15034.6 GBG93243.1 - 0.026 15.5 0.3 2.5 9.1 0.1 2.5 1 1 2 3 3 3 0 KRTAP type 7 family Microvir_J PF04726.13 GBG93243.1 - 0.23 11.4 9.1 6.2 6.9 0.1 3.5 3 0 0 3 3 3 0 Microvirus J protein LRR_6 PF13516.6 GBG93245.1 - 6e-50 163.1 38.1 0.00058 19.7 0.0 15.6 16 0 0 16 16 16 13 Leucine Rich repeat LRR_1 PF00560.33 GBG93245.1 - 3.6e-11 42.0 0.0 25 5.9 0.1 10.9 14 0 0 14 14 14 1 Leucine Rich Repeat LRR_4 PF12799.7 GBG93245.1 - 4.5e-09 36.5 22.9 0.14 12.6 0.0 8.0 5 3 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GBG93245.1 - 0.00043 20.0 25.1 0.65 9.8 0.2 8.9 5 3 1 7 7 7 3 Leucine rich repeat RVT_1 PF00078.27 GBG93247.1 - 4.7e-28 98.2 0.1 8.8e-28 97.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93247.1 - 1.6e-21 76.2 0.0 3.3e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93247.1 - 5.2e-21 74.9 0.0 1e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG93247.1 - 2.9e-08 34.2 0.0 5.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG93247.1 - 4.4e-08 33.0 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GBG93247.1 - 1.3e-06 28.8 0.0 2.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG93247.1 - 9.4e-05 22.5 0.1 0.00021 21.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 GBG93247.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DNTTIP1_dimer PF18192.1 GBG93248.1 - 0.0034 17.7 0.0 0.0079 16.5 0.0 1.6 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain LMBR1 PF04791.16 GBG93248.1 - 0.0064 15.5 1.8 0.0094 14.9 1.8 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Pex24p PF06398.11 GBG93248.1 - 0.36 9.8 3.9 0.61 9.0 3.9 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin RVT_1 PF00078.27 GBG93249.1 - 2.1e-09 37.3 0.0 3.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4487 PF14868.6 GBG93250.1 - 1.3e-31 110.1 9.6 6.2e-19 68.2 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4487) Knl1_RWD_C PF18210.1 GBG93250.1 - 0.0033 17.9 0.1 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 Knl1 RWD C-terminal domain DUF4487 PF14868.6 GBG93251.1 - 1.3e-31 110.1 9.6 6.2e-19 68.2 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4487) Knl1_RWD_C PF18210.1 GBG93251.1 - 0.0033 17.9 0.1 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 Knl1 RWD C-terminal domain SlyX PF04102.12 GBG93252.1 - 0.13 12.9 0.0 0.6 10.8 0.1 2.1 2 0 0 2 2 2 0 SlyX Integrase_H2C2 PF17921.1 GBG93253.1 - 1.1e-10 41.4 0.2 2.8e-10 40.1 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG93253.1 - 1.5e-10 41.0 0.0 3.6e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG93253.1 - 2.1e-10 40.8 0.0 4.8e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG93253.1 - 9.3e-05 22.9 0.0 0.00021 21.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93253.1 - 0.004 17.8 0.0 0.0087 16.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Jnk-SapK_ap_N PF09744.9 GBG93253.1 - 0.0046 17.2 4.9 0.0046 17.2 4.9 2.8 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 PriC PF07445.12 GBG93253.1 - 0.012 15.6 2.8 0.027 14.4 2.8 1.5 1 0 0 1 1 1 0 Primosomal replication protein priC Asp_protease PF09668.10 GBG93253.1 - 0.058 13.2 1.2 0.11 12.3 1.2 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 GBG93254.1 - 0.0018 18.5 1.3 0.034 14.4 0.0 3.1 3 1 0 3 3 3 1 Retrotransposon gag protein FUSC PF04632.12 GBG93254.1 - 0.032 12.8 2.5 0.041 12.4 2.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Laminin_II PF06009.12 GBG93254.1 - 0.037 14.0 0.2 0.057 13.4 0.2 1.3 1 0 0 1 1 1 0 Laminin Domain II ZapB PF06005.12 GBG93254.1 - 0.057 13.9 3.0 0.13 12.7 0.3 2.7 2 1 0 2 2 2 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 GBG93254.1 - 0.088 13.0 0.1 0.088 13.0 0.1 1.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 GBG93254.1 - 0.23 11.5 0.5 12 6.0 0.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5593 PF18007.1 GBG93254.1 - 0.28 11.9 1.2 63 4.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5593) CLZ PF16526.5 GBG93254.1 - 0.62 10.5 3.0 7.1 7.1 0.5 2.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels T4bSS_IcmS PF12608.8 GBG93255.1 - 0.081 13.2 4.7 0.24 11.7 4.0 2.3 1 1 1 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment UPF0225 PF17775.1 GBG93255.1 - 0.73 10.7 0.0 0.73 10.7 0.0 3.0 3 1 0 3 3 3 0 UPF0225 domain Noelin-1 PF12308.8 GBG93255.1 - 0.84 9.6 7.3 0.064 13.2 0.9 2.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein Myco_haema PF05692.12 GBG93255.1 - 3 6.7 5.2 0.43 9.5 0.8 1.7 2 0 0 2 2 2 0 Mycoplasma haemagglutinin RT_RNaseH_2 PF17919.1 GBG93256.1 - 3.6e-45 152.1 0.0 5e-25 87.4 0.0 3.2 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93256.1 - 3.3e-32 110.9 0.0 1.4e-21 76.7 0.0 3.1 4 0 0 4 4 4 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93256.1 - 1.9e-25 89.7 0.1 1.1e-23 83.9 0.1 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG93256.1 - 0.00027 21.1 0.0 0.001 19.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG93256.1 - 0.0028 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GBG93256.1 - 0.03 14.1 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease PIEZO PF15917.5 GBG93256.1 - 1.4 8.3 7.0 3.3 7.1 7.0 1.6 1 0 0 1 1 1 0 Piezo RVT_1 PF00078.27 GBG93257.1 - 4e-42 144.2 0.4 5.2e-30 104.6 0.1 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93257.1 - 4.6e-23 81.1 0.0 1e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93257.1 - 2.4e-22 79.2 0.0 4.7e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 GBG93257.1 - 6.6e-08 33.1 0.0 1.9e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93257.1 - 2.8e-07 31.0 0.0 5.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GBG93257.1 - 4.7e-06 26.4 0.0 1.2e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG93257.1 - 2.2e-05 24.3 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF659 PF04937.15 GBG93259.1 - 5.2e-11 42.6 0.0 5.4e-06 26.4 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF 659) WVELL PF14043.6 GBG93259.1 - 0.058 13.2 0.0 7.5 6.4 0.0 2.5 2 0 0 2 2 2 0 WVELL protein tify PF06200.14 GBG93259.1 - 0.09 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 tify domain Co_AT_N PF12557.8 GBG93260.1 - 0.46 10.5 4.9 1.3 9.0 4.9 1.9 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal XG_FTase PF03254.13 GBG93261.1 - 5e-13 48.5 0.2 1.6e-07 30.3 0.1 3.0 2 1 0 2 2 2 2 Xyloglucan fucosyltransferase Glyco_transf_11 PF01531.16 GBG93261.1 - 0.051 12.8 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 11 Cwf_Cwc_15 PF04889.12 GBG93262.1 - 0.95 9.1 16.2 1.4 8.6 16.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC27 PF09507.10 GBG93262.1 - 1.3 8.3 16.1 1.8 7.9 16.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop53 PF07767.11 GBG93262.1 - 4.5 6.6 20.9 8.8 5.6 20.9 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) LAP1C PF05609.12 GBG93262.1 - 6 5.9 10.0 7.5 5.5 10.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG93262.1 - 9.7 4.3 17.7 12 3.9 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_M6 PF05547.11 GBG93264.1 - 4.1e-16 58.5 4.0 4.8e-15 55.0 4.0 2.0 2 0 0 2 2 2 1 Immune inhibitor A peptidase M6 Ig_Tie2_1 PF10430.9 GBG93264.1 - 0.026 14.9 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 gag-asp_proteas PF13975.6 GBG93266.1 - 0.00022 21.7 0.6 0.00052 20.5 0.1 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Topo_Zn_Ribbon PF08272.11 GBG93266.1 - 0.019 14.6 0.2 0.041 13.6 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Asp_protease PF09668.10 GBG93266.1 - 0.02 14.7 0.2 0.034 13.9 0.2 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 GBG93266.1 - 0.025 15.2 0.1 0.07 13.8 0.1 1.8 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 GBG93266.1 - 0.066 13.3 2.1 0.12 12.5 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 GBG93266.1 - 0.17 11.6 0.1 0.32 10.8 0.1 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 GBG93267.1 - 5.9e-13 48.7 0.1 1.5e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG93267.1 - 1.1e-11 45.0 0.0 3.2e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG93267.1 - 6.3e-09 36.3 0.0 1.6e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93267.1 - 1.1e-06 29.2 0.0 2.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 GBG93267.1 - 5.1e-06 26.4 0.0 2e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93267.1 - 2e-05 24.8 0.0 5.6e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93267.1 - 2.7e-05 23.8 0.0 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 GBG93267.1 - 0.00048 19.9 0.1 0.00096 18.9 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG93267.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 GBG93268.1 - 3.8e-23 82.2 0.1 5.7e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hormone_3 PF00159.18 GBG93268.1 - 0.0064 16.5 0.2 0.3 11.2 0.1 3.2 2 0 0 2 2 2 1 Pancreatic hormone peptide MAP7 PF05672.11 GBG93275.1 - 0.17 11.6 25.8 0.21 11.3 25.8 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family VIR_N PF15912.5 GBG93275.1 - 0.21 11.1 8.5 0.27 10.8 8.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Chlam_PMP PF02415.17 GBG93277.1 - 0.00029 21.1 10.6 4.4 8.0 0.0 6.4 6 0 0 6 6 6 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Myb_DNA-bind_4 PF13837.6 GBG93277.1 - 0.02 15.2 0.3 0.14 12.6 0.1 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain C_GCAxxG_C_C PF09719.10 GBG93277.1 - 2.8 8.2 7.9 0.11 12.7 1.4 2.0 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) DUF659 PF04937.15 GBG93278.1 - 1.7e-11 44.2 0.0 2.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 GBG93279.1 - 1.6e-34 117.9 0.1 2.8e-34 117.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93279.1 - 2.1e-30 105.1 0.1 3.7e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Fasciclin PF02469.22 GBG93280.1 - 0.002 18.3 0.1 0.0032 17.7 0.1 1.3 1 0 0 1 1 1 1 Fasciclin domain RVT_1 PF00078.27 GBG93281.1 - 2.5e-21 76.2 0.1 3.3e-15 56.2 0.0 3.4 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG93281.1 - 0.00079 19.7 0.1 0.003 17.8 0.1 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein DUF2457 PF10446.9 GBG93284.1 - 0.094 11.8 6.9 0.097 11.8 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4900 PF16241.5 GBG93284.1 - 0.23 11.8 8.5 6.7 7.1 0.5 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4900) Apt1 PF10351.9 GBG93284.1 - 0.54 9.1 4.8 0.56 9.0 4.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain MMR1 PF08505.10 GBG93287.1 - 0.0031 17.8 4.5 0.0036 17.7 4.5 1.0 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein RRN3 PF05327.11 GBG93287.1 - 0.04 12.5 6.0 0.045 12.3 6.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 XRN_M PF17846.1 GBG93287.1 - 0.089 11.7 3.1 0.095 11.6 3.1 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Dala_Dala_lig_N PF01820.21 GBG93287.1 - 0.31 11.5 1.8 0.4 11.2 1.8 1.3 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus GvpL_GvpF PF06386.11 GBG93287.1 - 0.39 10.6 12.2 0.52 10.2 12.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF EIIBC-GUT_N PF03612.14 GBG93287.1 - 0.39 10.4 6.1 0.52 10.0 6.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus VIR_N PF15912.5 GBG93287.1 - 0.41 10.2 4.6 0.46 10.0 4.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DDHD PF02862.17 GBG93287.1 - 0.43 10.7 4.2 0.47 10.6 4.2 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 GBG93287.1 - 0.6 9.9 11.4 0.66 9.8 11.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPL5 PF18168.1 GBG93287.1 - 0.65 9.2 9.6 0.79 9.0 9.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 FAM176 PF14851.6 GBG93287.1 - 1.1 8.9 8.7 1.4 8.5 8.7 1.1 1 0 0 1 1 1 0 FAM176 family Holin_BhlA PF10960.8 GBG93287.1 - 1.7 8.7 9.3 4.2 7.4 9.2 1.8 1 1 0 1 1 1 0 BhlA holin family Tho2 PF11262.8 GBG93287.1 - 1.7 7.8 7.6 1.9 7.6 7.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PDCD7 PF16021.5 GBG93287.1 - 2.5 7.1 20.4 3.1 6.8 20.4 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 DUF1943 PF09172.11 GBG93287.1 - 2.7 7.1 7.3 3.4 6.8 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF4407 PF14362.6 GBG93287.1 - 3.3 7.0 9.7 4.3 6.6 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Paf1 PF03985.13 GBG93287.1 - 3.4 6.6 18.6 4.1 6.3 18.6 1.0 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 GBG93287.1 - 3.8 6.2 8.4 4.2 6.0 8.4 1.0 1 0 0 1 1 1 0 Presenilin Casc1_N PF15927.5 GBG93287.1 - 9.9 5.8 22.2 16 5.1 22.2 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus RVT_1 PF00078.27 GBG93288.1 - 4.3e-31 108.2 0.0 6.2e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_4 PF14392.6 GBG93288.1 - 0.049 13.4 0.6 0.14 11.9 0.6 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 GBG93288.1 - 0.16 11.9 4.1 0.33 11.0 4.1 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 GBG93289.1 - 2.2e-27 95.4 0.0 3e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93289.1 - 2.7e-25 88.3 0.0 3.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5387 PF17361.2 GBG93289.1 - 0.025 14.2 2.6 0.043 13.5 2.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5387) zf-CCHC PF00098.23 GBG93290.1 - 2.8e-16 58.8 13.9 7.6e-08 32.1 3.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 GBG93290.1 - 9.9e-06 25.3 6.1 0.033 14.0 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 GBG93290.1 - 0.00018 21.4 2.9 0.38 10.8 0.2 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 GBG93290.1 - 0.0016 18.3 9.9 0.15 11.9 1.0 2.7 2 0 0 2 2 2 2 Zinc knuckle Coagulin PF02035.15 GBG93290.1 - 0.009 15.9 0.3 1.5 8.6 0.1 2.4 2 0 0 2 2 2 1 Coagulin zf-CCHC_4 PF14392.6 GBG93290.1 - 0.014 15.1 7.0 0.81 9.5 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 GBG93290.1 - 0.043 13.5 4.9 2.5 7.9 0.4 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger IPP-2 PF04979.14 GBG93290.1 - 0.086 13.6 15.0 0.76 10.5 2.8 3.2 3 0 0 3 3 3 0 Protein phosphatase inhibitor 2 (IPP-2) DUF4193 PF13834.6 GBG93290.1 - 1.3 9.5 7.4 7.8 7.1 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4193) RT_RNaseH_2 PF17919.1 GBG93291.1 - 3.7e-24 84.7 0.0 1.2e-23 83.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93291.1 - 1.2e-20 73.8 0.0 3.2e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GBG93291.1 - 0.00011 22.4 0.3 0.00046 20.4 0.3 2.1 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 GBG93291.1 - 0.0097 16.2 0.1 0.27 11.5 0.0 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG93292.1 - 6.9e-28 97.7 0.1 1.2e-27 96.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93292.1 - 4.6e-21 74.7 0.0 8.8e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93292.1 - 5.1e-20 71.7 0.0 9.3e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93292.1 - 4.1e-18 65.2 0.2 8.3e-18 64.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 GBG93292.1 - 5.9e-10 39.0 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG93292.1 - 8e-07 29.6 0.0 1.6e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 GBG93292.1 - 1.9e-06 28.1 0.0 4.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 GBG93292.1 - 4.9e-05 23.8 0.0 0.00013 22.5 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG93292.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Aspartyl protease Histone PF00125.24 GBG93297.1 - 2.5e-14 53.7 0.2 6.5e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CDC45 PF02724.14 GBG93298.1 - 1.9 6.7 6.2 2.4 6.3 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RT_RNaseH_2 PF17919.1 GBG93299.1 - 4.4e-26 90.8 0.0 1e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93299.1 - 1.2e-22 80.2 0.0 2.8e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93299.1 - 0.00049 19.7 0.1 0.00087 18.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG93299.1 - 0.0062 15.7 0.1 0.028 13.5 0.0 1.9 2 0 0 2 2 2 1 Autophagy protein Apg17 NOA36 PF06524.12 GBG93300.1 - 0.11 11.8 10.1 0.12 11.6 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein PGA2 PF07543.12 GBG93300.1 - 0.94 9.5 15.6 1.6 8.7 15.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2201_N PF13203.6 GBG93300.1 - 0.95 9.0 11.8 1.4 8.5 11.8 1.4 1 1 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.12 GBG93300.1 - 3.4 7.4 7.7 3.3 7.4 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 GBG93300.1 - 3.8 7.1 9.2 7.3 6.2 9.2 1.6 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 GBG93300.1 - 5.7 4.9 13.7 6.5 4.7 13.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop53 PF07767.11 GBG93300.1 - 6.2 6.1 17.0 9 5.6 17.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 GBG93300.1 - 7.2 4.7 15.8 7.4 4.7 15.8 1.0 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 GBG93301.1 - 5.6e-25 88.2 0.0 1.1e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93301.1 - 6.8e-17 61.3 0.1 9.9e-15 54.4 0.0 2.9 2 1 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93301.1 - 8e-10 38.9 0.0 6.9e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase TolA_bind_tri PF16331.5 GBG93301.1 - 0.0016 18.5 3.3 0.0053 16.8 3.3 1.9 1 0 0 1 1 1 1 TolA binding protein trimerisation Retrotrans_gag PF03732.17 GBG93301.1 - 0.0067 16.7 1.1 0.049 13.9 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein YusW PF14039.6 GBG93301.1 - 0.015 15.8 0.4 0.096 13.2 0.2 2.5 2 0 0 2 2 2 0 YusW-like protein DUF1664 PF07889.12 GBG93301.1 - 0.098 12.7 1.1 0.31 11.1 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.18 GBG93301.1 - 0.92 8.8 3.6 3.3 6.9 0.4 2.7 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein ADIP PF11559.8 GBG93301.1 - 3.8 7.6 8.8 0.3 11.2 3.2 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Nop14 PF04147.12 GBG93302.1 - 0.00031 19.1 29.3 0.00036 18.9 29.3 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GBG93302.1 - 0.0084 15.6 33.7 0.013 15.0 33.7 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG93302.1 - 0.0094 14.3 23.3 0.013 13.8 23.3 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF5427 PF10310.9 GBG93302.1 - 0.11 11.4 16.1 0.15 11.0 16.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PPP4R2 PF09184.11 GBG93302.1 - 0.14 11.7 24.4 0.27 10.8 24.4 1.4 1 0 0 1 1 1 0 PPP4R2 DDHD PF02862.17 GBG93302.1 - 0.35 11.0 2.5 0.5 10.5 2.5 1.4 1 0 0 1 1 1 0 DDHD domain NOA36 PF06524.12 GBG93302.1 - 0.48 9.7 23.4 0.8 9.0 23.4 1.3 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 GBG93302.1 - 0.72 8.8 8.3 1 8.3 8.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 GBG93302.1 - 1 8.7 34.8 1.5 8.1 34.8 1.2 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 GBG93302.1 - 1 7.7 32.9 1.6 7.1 32.9 1.2 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 GBG93302.1 - 1.6 7.4 11.8 1.9 7.2 11.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.6 GBG93302.1 - 2.3 8.1 28.0 38 4.1 28.5 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Lin-8 PF03353.15 GBG93302.1 - 2.9 7.4 18.8 4.3 6.8 18.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Plasmodium_Vir PF05795.11 GBG93302.1 - 3.4 7.0 12.6 4.4 6.6 12.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Zip PF02535.22 GBG93302.1 - 3.9 6.6 9.9 5.3 6.2 9.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter LAP1C PF05609.12 GBG93302.1 - 4.3 6.3 16.8 5.7 5.9 16.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Serinc PF03348.15 GBG93302.1 - 4.7 6.0 5.5 9.6 5.0 5.5 1.5 1 1 0 1 1 1 0 Serine incorporator (Serinc) NARP1 PF12569.8 GBG93302.1 - 6.3 5.6 17.4 9 5.1 17.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SURF2 PF05477.11 GBG93302.1 - 7.4 6.2 18.6 12 5.5 18.6 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Presenilin PF01080.17 GBG93302.1 - 8.5 5.0 19.4 11 4.6 19.4 1.1 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 GBG93303.1 - 4.2 7.1 10.4 5.4 6.7 10.4 1.1 1 0 0 1 1 1 0 AAA domain N6_N4_Mtase PF01555.18 GBG93304.1 - 6.1e-10 39.2 0.0 1.5e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 DNA methylase CDC45 PF02724.14 GBG93304.1 - 0.0018 16.7 14.4 0.0022 16.4 14.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GBG93304.1 - 0.011 14.0 25.9 0.015 13.5 25.9 1.1 1 0 0 1 1 1 0 Nop14-like family Cons_hypoth95 PF03602.15 GBG93304.1 - 0.016 14.8 0.0 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 RRN3 PF05327.11 GBG93304.1 - 0.045 12.3 12.4 0.062 11.9 12.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BSP_II PF05432.11 GBG93304.1 - 0.13 11.9 30.7 0.21 11.2 30.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SDA1 PF05285.12 GBG93304.1 - 0.22 10.9 26.6 0.3 10.5 26.6 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG93304.1 - 0.31 10.3 22.1 0.44 9.8 22.1 1.2 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 GBG93304.1 - 0.39 10.5 17.0 0.57 10.0 17.0 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Mpp10 PF04006.12 GBG93304.1 - 1.3 7.4 30.9 1.8 6.9 30.9 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 GBG93304.1 - 1.4 7.8 9.5 2.5 7.0 9.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) eIF3_subunit PF08597.10 GBG93304.1 - 1.8 8.4 25.6 2.7 7.8 25.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 GBG93304.1 - 2.2 7.0 13.7 3.4 6.3 13.7 1.3 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 GBG93304.1 - 2.4 6.0 7.7 3.1 5.6 7.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Raftlin PF15250.6 GBG93304.1 - 2.5 6.8 11.0 3.4 6.3 11.0 1.1 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 GBG93304.1 - 3.2 6.7 8.1 4.4 6.2 8.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 GBG93304.1 - 3.2 6.4 9.8 4.4 6.0 9.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 GBG93304.1 - 3.5 6.3 12.4 6.1 5.5 12.4 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4746 PF15928.5 GBG93304.1 - 4.3 6.7 26.2 6.5 6.1 26.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RPN2_C PF18004.1 GBG93304.1 - 7.2 6.5 20.2 16 5.4 20.2 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPL5 PF18168.1 GBG93304.1 - 7.4 5.8 6.9 11 5.2 6.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 GREB1 PF15782.5 GBG93304.1 - 9.9 3.1 11.5 13 2.7 11.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SDA1 PF05285.12 GBG93306.1 - 0.00019 21.0 18.9 0.053 12.9 16.4 2.0 2 0 0 2 2 2 2 SDA1 DUF1980 PF09323.10 GBG93306.1 - 0.23 11.4 8.4 0.29 11.0 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 GBG93306.1 - 0.24 10.1 4.1 0.29 9.8 4.1 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GBG93306.1 - 0.33 9.7 4.9 0.42 9.3 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CPSF100_C PF13299.6 GBG93306.1 - 0.38 10.9 9.3 0.4 10.8 6.6 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EIIBC-GUT_N PF03612.14 GBG93306.1 - 1.6 8.4 5.9 1.5 8.5 3.1 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Sigma70_ner PF04546.13 GBG93306.1 - 1.7 8.5 21.5 3.1 7.6 13.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region RR_TM4-6 PF06459.12 GBG93306.1 - 2.4 7.9 17.1 4.8 6.9 13.3 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RXT2_N PF08595.11 GBG93306.1 - 9.3 6.3 16.2 1 9.4 7.4 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Glyco_hydro_17 PF00332.18 GBG93307.1 - 6e-50 170.6 0.0 8e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.13 GBG93307.1 - 1.3e-34 118.7 1.9 2.1e-19 70.0 0.1 2.6 2 0 0 2 2 2 2 X8 domain Glyco_hydro_17 PF00332.18 GBG93308.1 - 1.8e-43 149.3 0.0 2.6e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 X8 PF07983.13 GBG93308.1 - 1.2e-34 118.9 1.9 2e-19 70.0 0.1 2.6 2 0 0 2 2 2 2 X8 domain RT_RNaseH_2 PF17919.1 GBG93309.1 - 2.8e-24 85.1 0.0 6.2e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93309.1 - 3.1e-15 56.3 0.0 9e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93309.1 - 2.1e-13 50.3 0.0 1.7e-11 44.1 0.0 2.4 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 GBG93309.1 - 8.5e-09 35.3 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GBG93309.1 - 8.1e-07 29.6 0.0 2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93309.1 - 9.6e-06 26.1 0.0 2.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 GBG93309.1 - 2.1e-05 24.5 4.3 4.4e-05 23.5 4.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GBG93309.1 - 2.3e-05 24.6 3.6 0.033 14.4 0.0 3.3 3 0 0 3 3 3 2 Retrotransposon gag protein rve PF00665.26 GBG93309.1 - 0.00036 20.7 0.0 0.0013 18.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 GBG93309.1 - 0.024 14.4 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.12 GBG93309.1 - 1.4 9.6 3.9 1.1 9.9 0.4 2.6 2 0 0 2 2 2 0 SlyX SOUL PF04832.12 GBG93310.1 - 9.5e-11 42.1 0.0 1.1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein Muskelin_N PF06588.11 GBG93310.1 - 0.0045 16.9 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus RVT_1 PF00078.27 GBG93311.1 - 4e-32 111.5 0.0 7.6e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 GBG93312.1 - 0.0044 16.9 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-CCHC PF00098.23 GBG93313.1 - 9.6e-20 69.7 21.3 9.1e-08 31.9 3.1 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 GBG93313.1 - 3.9e-06 26.6 12.0 0.012 15.5 1.3 3.4 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 GBG93313.1 - 0.00015 21.6 7.4 0.28 11.2 0.1 3.9 4 0 0 4 4 3 2 Zinc knuckle Coagulin PF02035.15 GBG93313.1 - 0.00052 20.0 2.7 3.2 7.6 0.1 3.6 3 0 0 3 3 3 2 Coagulin IPP-2 PF04979.14 GBG93313.1 - 0.0027 18.5 27.1 0.026 15.3 0.6 4.9 4 0 0 4 4 4 2 Protein phosphatase inhibitor 2 (IPP-2) GvpL_GvpF PF06386.11 GBG93313.1 - 0.014 15.4 42.8 0.22 11.4 6.5 4.3 4 0 0 4 4 4 0 Gas vesicle synthesis protein GvpL/GvpF zf-CCHC_6 PF15288.6 GBG93313.1 - 0.025 14.4 19.6 0.18 11.7 1.0 4.1 4 0 0 4 4 4 0 Zinc knuckle TetR_C_27 PF17935.1 GBG93313.1 - 0.052 13.6 0.4 0.052 13.6 0.4 3.7 4 1 1 5 5 5 0 Tetracyclin repressor-like, C-terminal domain Palm_thioest PF02089.15 GBG93313.1 - 0.24 11.2 5.5 4.9 6.9 0.0 3.9 4 0 0 4 4 4 0 Palmitoyl protein thioesterase STPPase_N PF16891.5 GBG93313.1 - 0.25 11.8 2.1 36 4.9 0.1 3.4 3 0 0 3 3 3 0 Serine-threonine protein phosphatase N-terminal domain zf-CCHC_5 PF14787.6 GBG93313.1 - 0.43 10.3 11.4 5 6.9 1.2 3.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger DUF4193 PF13834.6 GBG93313.1 - 1.1 9.8 14.7 4.8 7.7 0.5 4.1 4 0 0 4 4 3 0 Domain of unknown function (DUF4193) Stevor PF17410.2 GBG93313.1 - 1.3 8.5 30.8 0.92 9.0 2.5 4.1 4 0 0 4 4 4 0 Subtelomeric Variable Open Reading frame zf-CCHC_4 PF14392.6 GBG93313.1 - 2.9 7.7 18.2 1 9.1 1.0 3.9 4 0 0 4 4 4 0 Zinc knuckle Pyrophosphatase PF00719.19 GBG93314.1 - 9e-55 184.9 0.1 1e-54 184.6 0.1 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pilus_CpaD PF09476.10 GBG93314.1 - 0.0075 16.0 0.0 0.0088 15.8 0.0 1.2 1 0 0 1 1 1 1 Pilus biogenesis CpaD protein (pilus_cpaD) AIG1 PF04548.16 GBG93315.1 - 1.1e-07 31.4 0.3 1.4e-07 31.0 0.3 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 GBG93315.1 - 1.9e-06 27.9 0.0 2.2e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 GBG93315.1 - 3.3e-05 24.3 0.1 4e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GBG93315.1 - 0.00038 20.5 0.6 0.00055 20.0 0.2 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Sigma54_activat PF00158.26 GBG93315.1 - 0.00084 19.1 0.0 0.00098 18.9 0.0 1.1 1 0 0 1 1 1 1 Sigma-54 interaction domain NB-ARC PF00931.22 GBG93315.1 - 0.0017 17.6 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain Septin PF00735.18 GBG93315.1 - 0.0068 15.7 0.1 0.0084 15.4 0.1 1.1 1 0 0 1 1 1 1 Septin DUF815 PF05673.13 GBG93315.1 - 0.0076 15.4 0.0 0.0079 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 GBG93315.1 - 0.013 16.1 0.4 1.6 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GBG93315.1 - 0.015 15.8 0.6 0.023 15.2 0.6 1.3 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 GBG93315.1 - 0.016 14.9 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 GBG93315.1 - 0.021 14.0 0.1 0.025 13.7 0.1 1.0 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 GBG93315.1 - 0.022 14.5 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 GBG93315.1 - 0.035 13.6 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 GBG93315.1 - 0.043 13.9 0.7 0.07 13.2 0.7 1.3 1 0 0 1 1 1 0 Dynamin family TniB PF05621.11 GBG93315.1 - 0.074 12.5 0.0 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein IIGP PF05049.13 GBG93315.1 - 0.084 11.9 0.0 0.098 11.7 0.0 1.0 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 GBG93315.1 - 0.099 12.9 0.2 0.16 12.2 0.2 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 GBG93315.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Hpr_kinase_C PF07475.12 GBG93315.1 - 0.12 11.9 0.5 0.17 11.4 0.5 1.3 1 1 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA PF00004.29 GBG93315.1 - 0.13 12.7 0.1 0.32 11.4 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GBG93315.1 - 0.13 12.2 0.3 0.83 9.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.12 GBG93315.1 - 0.14 11.5 0.2 0.24 10.7 0.2 1.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PPO1_KFDV PF12143.8 GBG93315.1 - 0.15 12.1 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) DUF87 PF01935.17 GBG93315.1 - 0.16 12.0 1.1 0.22 11.6 0.9 1.3 1 1 0 1 1 1 0 Helicase HerA, central domain Myb_DNA-bind_4 PF13837.6 GBG93316.1 - 2.3e-08 34.3 0.4 4.2e-08 33.4 0.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF973 PF06157.11 GBG93317.1 - 0.02 13.9 33.4 0.0075 15.4 18.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF973) EpsG PF14897.6 GBG93317.1 - 0.13 11.5 5.0 0.76 9.0 0.5 2.4 2 0 0 2 2 2 0 EpsG family DUF4133 PF13571.6 GBG93317.1 - 0.52 10.7 35.9 1.5 9.2 0.5 6.1 5 1 1 6 6 6 0 Domain of unknown function (DUF4133) MIG-14_Wnt-bd PF06664.12 GBG93317.1 - 0.66 9.1 17.0 0.045 13.0 4.3 2.2 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF3671 PF12420.8 GBG93317.1 - 1.9 8.6 20.7 2.9e+02 1.6 9.0 3.5 1 1 1 2 2 2 0 Protein of unknown function Catalase-rel PF06628.12 GBG93317.1 - 9.5 6.5 13.6 17 5.7 0.2 5.3 5 2 1 6 6 6 0 Catalase-related immune-responsive Metallophos PF00149.28 GBG93318.1 - 5.5e-06 27.0 0.2 7.3e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GBG93318.1 - 0.0015 18.9 0.2 0.003 18.0 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Put_Phosphatase PF06888.12 GBG93319.1 - 0.083 12.3 0.0 0.89 8.9 0.0 2.4 3 0 0 3 3 3 0 Putative Phosphatase RVT_1 PF00078.27 GBG93321.1 - 1.3e-08 34.7 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG93321.1 - 6.1e-08 32.9 0.0 4.7e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93321.1 - 0.00017 21.5 0.0 0.00047 20.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Lamprin PF06403.11 GBG93321.1 - 0.4 10.7 5.1 0.8 9.7 5.1 1.4 1 0 0 1 1 1 0 Lamprin TPR_14 PF13428.6 GBG93323.1 - 1.8e-07 31.4 0.0 0.0028 18.4 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GBG93323.1 - 1.8e-06 27.6 0.0 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GBG93323.1 - 8.4e-05 23.0 0.0 0.00011 22.7 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 GBG93323.1 - 0.023 15.3 0.1 0.46 11.2 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 GBG93323.1 - 0.04 13.7 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_1 PF12854.7 GBG93323.1 - 0.047 13.4 0.2 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 PPR repeat PPR PF01535.20 GBG93323.1 - 0.065 13.5 0.1 2.2 8.7 0.0 2.2 2 0 0 2 2 2 0 PPR repeat Suf PF05843.14 GBG93323.1 - 0.071 13.1 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TPR_15 PF13429.6 GBG93323.1 - 0.074 12.2 0.0 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GBG93323.1 - 0.086 12.8 0.1 0.32 11.0 0.0 1.7 1 1 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 GBG93323.1 - 0.1 13.1 0.0 8.6 7.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 GBG93323.1 - 0.12 12.6 0.0 0.75 10.0 0.0 1.9 1 1 1 2 2 2 0 HemY protein N-terminus TPR_8 PF13181.6 GBG93323.1 - 0.13 12.5 0.0 0.68 10.3 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GBG93323.1 - 0.15 12.1 0.0 24 5.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 GBG93324.1 - 6.5e-15 55.3 5.1 0.00013 22.7 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG93324.1 - 3.5e-09 36.9 0.0 0.0068 16.7 0.0 3.0 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GBG93324.1 - 1.2e-05 24.5 0.2 0.00039 19.5 0.0 2.0 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RT_RNaseH_2 PF17919.1 GBG93325.1 - 4.6e-31 106.8 0.0 8.2e-31 106.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93325.1 - 5e-29 100.7 0.0 9.3e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93325.1 - 7.9e-20 70.7 0.1 1.7e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG93325.1 - 3.6e-12 46.5 0.0 8.5e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG93325.1 - 1.6e-10 40.9 0.0 3.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GBG93325.1 - 0.00043 20.4 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 GBG93329.1 - 2.4e-16 60.0 0.0 4.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 GBG93329.1 - 2.5e-08 33.7 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GBG93329.1 - 0.083 12.7 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Toprim_N PF08275.11 GBG93332.1 - 1.8e-05 24.8 7.9 31 4.6 0.0 7.3 2 2 7 9 9 9 0 DNA primase catalytic core, N-terminal domain RTA1 PF04479.13 GBG93332.1 - 0.00016 21.4 12.4 17 4.9 0.1 7.2 1 1 8 9 9 9 0 RTA1 like protein PapC_C PF13953.6 GBG93332.1 - 0.00067 19.4 26.7 2.7 7.9 1.3 7.7 1 1 9 10 10 10 5 PapC C-terminal domain SH3_19 PF18597.1 GBG93332.1 - 0.00079 19.2 26.1 12 5.8 0.2 7.8 8 0 0 8 8 8 2 Myosin X N-terminal SH3 domain DCR PF14047.6 GBG93332.1 - 0.0045 17.2 9.6 16 5.8 0.1 6.2 1 1 8 9 9 9 0 Dppa2/4 conserved region Pirin_C PF05726.13 GBG93332.1 - 0.028 14.8 1.1 21 5.5 0.7 3.4 1 1 1 2 2 2 0 Pirin C-terminal cupin domain ImpE PF07024.13 GBG93332.1 - 0.19 11.8 16.3 34 4.6 0.1 6.5 1 1 8 9 9 9 0 ImpE protein DdrB PF12747.7 GBG93332.1 - 0.65 9.8 17.9 11 5.8 1.3 5.1 1 1 6 7 7 7 0 DdrB-like protein DUF2917 PF11142.8 GBG93332.1 - 2.2 7.8 26.7 0.55 9.7 1.1 6.0 2 2 5 7 7 7 0 Protein of unknown function (DUF2917) ATP_transf PF09830.9 GBG93332.1 - 2.2 8.5 13.9 1.1e+02 3.1 0.1 6.4 2 2 5 7 7 7 0 ATP adenylyltransferase KH_6 PF15985.5 GBG93332.1 - 4.4 7.7 21.4 66 4.0 0.1 6.9 8 0 0 8 8 8 0 KH domain Pro_isomerase PF00160.21 GBG93334.1 - 1.7e-48 164.9 0.1 1.9e-48 164.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RR_TM4-6 PF06459.12 GBG93335.1 - 0.63 9.8 15.2 1.5 8.6 3.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 GBG93335.1 - 3.8 7.9 10.4 14 6.1 1.3 2.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF2052 PF09747.9 GBG93335.1 - 4.4 7.4 28.7 2.7 8.1 7.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) NDK PF00334.19 GBG93336.1 - 8.4e-06 25.8 0.0 9.2e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.19 GBG93337.1 - 7.8e-06 25.9 0.0 8.5e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NiFe_hyd_3_EhaA PF17367.2 GBG93338.1 - 0.058 13.5 0.4 0.1 12.7 0.1 1.5 1 1 1 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A Tho2 PF11262.8 GBG93340.1 - 1.6 7.8 11.5 2.5 7.2 11.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ATG16 PF08614.11 GBG93344.1 - 0.015 15.5 19.9 0.015 15.5 19.9 2.7 3 1 1 4 4 3 0 Autophagy protein 16 (ATG16) LRS4 PF10422.9 GBG93344.1 - 0.042 13.4 9.8 0.093 12.3 9.8 1.6 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Fib_alpha PF08702.10 GBG93344.1 - 1.1 9.4 13.9 2.6 8.2 10.7 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 GBG93344.1 - 1.5 6.7 3.9 2.3 6.1 3.9 1.3 1 0 0 1 1 1 0 Prominin AAA_13 PF13166.6 GBG93344.1 - 1.6 7.3 11.1 2.4 6.7 11.1 1.2 1 0 0 1 1 1 0 AAA domain Bap31_Bap29_C PF18035.1 GBG93344.1 - 1.6 8.8 15.1 5.3 7.1 1.2 3.2 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain FlaC_arch PF05377.11 GBG93344.1 - 2.2 8.7 21.4 1 9.8 3.9 3.5 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) DAP_B PF07930.12 GBG93344.1 - 2.7 7.9 5.9 3.8 7.4 3.4 2.2 2 0 0 2 2 2 0 D-aminopeptidase, domain B V_ATPase_I PF01496.19 GBG93344.1 - 2.8 5.7 9.7 4.4 5.1 9.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.11 GBG93344.1 - 3.1 7.3 7.6 6.2 6.4 7.6 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CK2S PF15011.6 GBG93344.1 - 3.7 7.4 12.5 35 4.2 8.7 3.3 2 1 0 2 2 2 0 Casein Kinase 2 substrate IFT57 PF10498.9 GBG93344.1 - 5.5 5.8 21.3 13 4.6 21.3 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Allexi_40kDa PF05549.11 GBG93344.1 - 5.8 6.4 8.5 5.9 6.3 4.3 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4061 PF13270.6 GBG93344.1 - 6.3 7.2 11.7 1.2 9.5 6.2 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4061) RT_RNaseH_2 PF17919.1 GBG93345.1 - 5.3e-28 97.0 0.0 1e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93345.1 - 1.3e-27 96.1 0.0 2.2e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93345.1 - 2.9e-14 53.1 0.0 4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2249 PF10006.9 GBG93345.1 - 0.007 16.2 0.1 0.37 10.7 0.0 2.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2249) RNA_pol_Rpc4 PF05132.14 GBG93345.1 - 3.2 8.2 6.2 6.8 7.1 6.2 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 PPP4R2 PF09184.11 GBG93345.1 - 4 7.0 20.1 5.8 6.4 20.1 1.2 1 0 0 1 1 1 0 PPP4R2 BNR PF02012.20 GBG93346.1 - 2.1 8.7 3.7 1.7 8.9 0.2 2.9 3 0 0 3 3 3 0 BNR/Asp-box repeat IHABP4_N PF16174.5 GBG93346.1 - 7.4 7.1 12.0 0.45 11.1 6.1 1.9 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal RT_RNaseH_2 PF17919.1 GBG93348.1 - 8.2e-12 45.0 0.0 2.3e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93348.1 - 1.5e-10 41.0 0.0 3.1e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GBG93348.1 - 4.5e-10 39.7 0.0 1.9e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93349.1 - 6.1e-25 88.0 0.1 1.3e-24 86.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lipin_mid PF16876.5 GBG93349.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Vps54 PF07928.12 GBG93353.1 - 8.4e-21 74.8 0.1 1.6e-20 73.9 0.1 1.4 1 0 0 1 1 1 1 Vps54-like protein Serpin PF00079.20 GBG93355.1 - 3.2e-68 230.8 0.0 4e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Dapper PF15268.6 GBG93357.1 - 0.67 8.8 12.9 0.72 8.6 12.9 1.1 1 0 0 1 1 1 0 Dapper FAM76 PF16046.5 GBG93357.1 - 2.7 7.3 16.4 4.1 6.7 16.4 1.4 1 0 0 1 1 1 0 FAM76 protein Zip PF02535.22 GBG93357.1 - 8.3 5.5 17.7 9 5.4 12.8 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Chromo PF00385.24 GBG93360.1 - 4.9e-11 42.4 0.0 9.4e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GBG93361.1 - 2.8e-10 40.4 0.0 7.8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 GBG93361.1 - 8.5e-08 32.7 0.0 2.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GBG93361.1 - 1.5e-06 28.7 0.1 3.5e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GBG93361.1 - 0.02 15.2 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG93361.1 - 0.13 12.1 0.3 0.25 11.1 0.3 1.4 1 0 0 1 1 1 0 Aspartyl protease RNA_polI_A34 PF08208.11 GBG93361.1 - 1 9.4 14.0 1.7 8.7 14.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Sec6 PF06046.13 GBG93361.1 - 1 7.6 6.0 2 6.7 6.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec6 NARP1 PF12569.8 GBG93361.1 - 3.2 6.6 8.4 4.8 6.0 8.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 F-box-like PF12937.7 GBG93363.1 - 0.00094 19.0 1.9 0.0014 18.5 0.8 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GBG93363.1 - 0.074 13.0 2.7 0.25 11.2 2.7 1.9 1 0 0 1 1 1 0 F-box domain LegC3_N PF18654.1 GBG93363.1 - 0.19 11.0 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain DAZAP2 PF11029.8 GBG93363.1 - 0.77 10.7 6.4 0.11 13.5 1.0 2.2 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) SPX PF03105.19 GBG93363.1 - 1.4 8.7 14.6 2.5 7.9 14.6 1.2 1 0 0 1 1 1 0 SPX domain PTPRCAP PF15713.5 GBG93364.1 - 0.099 12.9 5.7 0.12 12.7 5.7 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CUE PF02845.16 GBG93364.1 - 0.11 12.2 0.0 0.58 9.9 0.0 2.1 1 1 1 2 2 2 0 CUE domain BNIP3 PF06553.12 GBG93364.1 - 0.39 10.4 3.4 0.47 10.1 3.4 1.1 1 0 0 1 1 1 0 BNIP3 GOLD_2 PF13897.6 GBG93364.1 - 0.7 10.4 2.6 0.91 10.0 2.6 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FAM176 PF14851.6 GBG93364.1 - 0.76 9.4 6.3 1 9.0 6.3 1.2 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 GBG93364.1 - 2.4 6.4 5.9 2.3 6.4 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG93364.1 - 3.8 5.5 6.7 4.2 5.3 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PAC1 PF16094.5 GBG93364.1 - 5.2 6.1 7.0 7.1 5.7 7.0 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 RPN2_C PF18004.1 GBG93367.1 - 0.00052 20.0 2.9 0.00067 19.6 2.9 1.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain Myc_N PF01056.18 GBG93367.1 - 0.086 12.7 4.0 0.095 12.6 4.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 GBG93367.1 - 0.1 11.9 0.9 0.11 11.8 0.9 1.1 1 0 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.12 GBG93367.1 - 0.36 10.6 4.2 0.43 10.4 4.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.6 GBG93367.1 - 0.91 9.9 6.9 0.22 11.9 3.2 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2119 PF09892.9 GBG93369.1 - 0.14 11.6 0.2 0.22 10.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) SDA1 PF05285.12 GBG93370.1 - 10 5.5 19.2 13 5.1 19.2 1.1 1 0 0 1 1 1 0 SDA1 DUF1264 PF06884.11 GBG93371.1 - 4.2e-33 114.4 2.3 5e-33 114.1 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Thioredoxin_7 PF13899.6 GBG93371.1 - 0.021 15.0 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like rve PF00665.26 GBG93372.1 - 2.6e-12 47.0 0.0 1.2e-11 44.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GBG93372.1 - 1.7e-05 24.4 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG93372.1 - 0.042 14.4 0.2 0.18 12.4 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease zf-CCHC_5 PF14787.6 GBG93373.1 - 0.052 13.3 0.6 0.052 13.3 0.6 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RT_RNaseH PF17917.1 GBG93374.1 - 2.1e-22 79.4 0.0 5.5e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93374.1 - 8e-21 74.0 0.0 1.9e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93374.1 - 2.9e-10 40.1 0.0 5.1e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GBG93374.1 - 1.7e-08 34.9 0.3 5.2e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93374.1 - 3.6e-05 24.3 0.3 0.00012 22.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 GBG93374.1 - 0.0013 18.6 0.8 0.0024 17.7 0.8 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG93374.1 - 0.015 15.6 0.0 0.052 13.9 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Lamprin PF06403.11 GBG93374.1 - 3.5 7.6 8.8 7.2 6.6 8.8 1.4 1 0 0 1 1 1 0 Lamprin zf-CCHC PF00098.23 GBG93375.1 - 1.7e-06 27.8 1.6 3.6e-06 26.8 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GBG93375.1 - 0.0069 16.1 2.0 0.016 14.9 2.0 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CpXC PF14353.6 GBG93375.1 - 0.4 10.7 8.0 3.4 7.7 0.0 3.3 2 1 0 2 2 2 0 CpXC protein DDE_Tnp_4 PF13359.6 GBG93376.1 - 1.8e-26 92.7 0.0 2.9e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GBG93376.1 - 4.3e-11 42.8 0.0 6.2e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein HSP20 PF00011.21 GBG93377.1 - 5.7e-28 97.1 0.1 8.2e-28 96.6 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG93377.1 - 2.7e-08 33.2 0.1 6.3e-08 32.1 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 GBG93378.1 - 5.5e-27 93.9 0.1 9.3e-27 93.2 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG93378.1 - 7.4e-07 28.6 0.1 2.5e-06 27.0 0.1 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 GBG93378.1 - 0.017 15.4 1.1 0.032 14.5 0.1 1.9 2 0 0 2 2 2 0 BON domain HSP20 PF00011.21 GBG93379.1 - 3.8e-28 97.6 0.2 4.9e-28 97.3 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GBG93379.1 - 7.8e-08 31.8 0.1 1.9e-07 30.6 0.1 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA MG4 PF17789.1 GBG93382.1 - 0.14 12.3 0.0 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 Macroglobulin domain MG4 DUF1240 PF06836.12 GBG93384.1 - 0.059 13.9 0.1 0.075 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) bZIP_1 PF00170.21 GBG93385.1 - 2.2e-12 46.9 11.6 2.9e-12 46.5 11.0 1.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GBG93385.1 - 2e-06 27.8 12.0 2e-06 27.8 12.0 2.1 1 1 1 2 2 2 1 Basic region leucine zipper Nucleo_P87 PF07267.11 GBG93385.1 - 0.04 12.8 4.9 0.047 12.5 4.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIA PF03153.13 GBG93385.1 - 0.95 9.4 7.7 1.1 9.2 7.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.12 GBG93385.1 - 1.7 6.5 4.0 1.8 6.4 4.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein bZIP_Maf PF03131.17 GBG93385.1 - 2.3 8.8 12.8 1.8 9.1 9.9 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor H_PPase PF03030.16 GBG93387.1 - 5e-26 91.5 0.2 5.5e-26 91.4 0.2 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Phage_TAC_12 PF12363.8 GBG93388.1 - 0.25 11.8 10.2 45 4.5 0.0 6.5 3 2 5 8 8 8 0 Phage tail assembly chaperone protein, TAC Aa_trans PF01490.18 GBG93389.1 - 8.8e-13 47.7 6.5 1e-12 47.5 6.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 GBG93389.1 - 0.0057 15.5 3.4 0.0071 15.2 3.4 1.2 1 0 0 1 1 1 1 Spore germination protein Nop14 PF04147.12 GBG93391.1 - 0.077 11.2 39.6 0.087 11.0 39.6 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GBG93391.1 - 0.11 11.9 39.5 0.12 11.7 39.5 1.0 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 GBG93391.1 - 0.16 12.0 53.5 0.18 11.8 53.5 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2201_N PF13203.6 GBG93391.1 - 0.18 11.4 21.4 0.2 11.2 21.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.12 GBG93391.1 - 1.2 9.0 35.5 1.4 8.7 35.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 GBG93391.1 - 1.2 7.5 42.1 1.5 7.2 42.1 1.0 1 0 0 1 1 1 0 Mpp10 protein RRN3 PF05327.11 GBG93391.1 - 1.6 7.2 26.4 1.8 7.0 26.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GBG93391.1 - 1.8 6.7 37.2 2.1 6.6 37.2 1.0 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 GBG93391.1 - 2.5 7.8 24.2 3 7.5 24.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF913 PF06025.12 GBG93391.1 - 3.3 6.6 18.9 4.3 6.2 18.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CCSAP PF15748.5 GBG93391.1 - 3.5 7.7 29.9 4.2 7.5 29.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Sigma70_ner PF04546.13 GBG93391.1 - 3.6 7.4 32.9 4.4 7.1 32.9 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Peptidase_S30 PF01577.16 GBG93391.1 - 3.9 7.0 18.0 4.9 6.7 18.0 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease Ctr PF04145.15 GBG93391.1 - 4.7 7.8 8.6 6.9 7.3 8.6 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Nop53 PF07767.11 GBG93391.1 - 5 6.4 44.4 6 6.2 44.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM60A PF15396.6 GBG93391.1 - 6 6.8 18.7 7.1 6.6 18.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RNA_polI_A34 PF08208.11 GBG93391.1 - 7.2 6.7 42.4 8.4 6.4 42.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Dsh_C PF12316.8 GBG93391.1 - 7.9 6.8 10.9 9 6.6 10.9 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Gp_dh_C PF02800.20 GBG93392.1 - 3.2e-69 231.6 0.0 4.2e-69 231.2 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GBG93392.1 - 9.5e-39 131.8 0.0 4.5e-38 129.7 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GBG93392.1 - 0.0071 16.5 0.3 0.021 14.9 0.0 2.0 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Radical_SAM PF04055.21 GBG93392.1 - 0.2 12.0 0.0 1.9 8.8 0.0 2.0 2 0 0 2 2 2 0 Radical SAM superfamily Pkinase PF00069.25 GBG93393.1 - 1.7e-40 139.1 0.0 9.3e-40 136.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG93393.1 - 1.8e-35 122.5 0.0 1e-34 120.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GBG93393.1 - 0.00037 20.5 0.1 0.0014 18.6 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GBG93393.1 - 0.02 13.7 0.1 0.048 12.4 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase EphA2_TM PF14575.6 GBG93393.1 - 0.19 12.6 0.2 2.2 9.2 0.0 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 GBG93393.1 - 0.63 10.1 3.9 1.5 9.0 3.9 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DsrH PF04077.12 GBG93394.1 - 0.0077 16.3 0.1 26 5.0 0.0 5.1 1 1 7 8 8 8 1 DsrH like protein SeleniumBinding PF11524.8 GBG93394.1 - 7.2 7.1 15.6 71 3.9 1.5 5.8 1 1 4 6 6 6 0 Selenium binding protein PDZ PF00595.24 GBG93396.1 - 2.5e-05 24.6 11.7 2.4 8.6 0.1 6.5 4 2 2 6 6 6 5 PDZ domain Mucin-like PF16058.5 GBG93396.1 - 0.017 15.2 2.2 6.4 6.9 0.0 4.1 3 2 1 4 4 4 0 Mucin-like Pkinase_Tyr PF07714.17 GBG93398.1 - 3.9e-31 108.3 0.0 5.7e-10 38.9 0.0 4.5 4 1 0 4 4 4 4 Protein tyrosine kinase Pkinase PF00069.25 GBG93398.1 - 3.9e-26 92.0 0.0 4.6e-08 32.8 0.0 4.7 4 2 0 4 4 4 4 Protein kinase domain TctB PF07331.11 GBG93398.1 - 0.0024 18.2 0.2 3.8 7.8 0.0 2.4 2 0 0 2 2 2 2 Tripartite tricarboxylate transporter TctB family DUF3956 PF13104.6 GBG93398.1 - 0.0047 17.1 0.4 5.4 7.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3956) CcmD PF04995.14 GBG93398.1 - 1.2 9.3 3.5 39 4.4 0.3 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SPX PF03105.19 GBG93398.1 - 1.6 8.5 42.3 4.4 7.1 17.1 2.2 2 0 0 2 2 2 0 SPX domain Cupin_8 PF13621.6 GBG93401.1 - 3.1e-49 168.0 0.0 6e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GBG93401.1 - 1.8e-12 47.4 0.1 5e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 GBG93401.1 - 0.0057 17.1 0.0 0.024 15.1 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-TRAF_2 PF15965.5 GBG93401.1 - 0.04 14.4 0.1 0.04 14.4 0.1 2.4 2 0 0 2 2 2 0 TRAF-like zinc-finger PGA2 PF07543.12 GBG93401.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 MMR_HSR1 PF01926.23 GBG93402.1 - 2.5e-06 27.5 0.1 2.1e-05 24.6 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GBG93402.1 - 0.00017 21.6 0.0 0.00079 19.4 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 GBG93402.1 - 0.00019 20.8 0.0 0.74 9.1 0.0 2.8 2 0 0 2 2 2 2 AIG1 family Septin PF00735.18 GBG93402.1 - 0.00033 20.0 0.0 0.0011 18.4 0.0 1.8 1 1 0 1 1 1 1 Septin AAA_29 PF13555.6 GBG93402.1 - 0.00035 20.3 0.0 0.002 17.8 0.0 2.3 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GBG93402.1 - 0.00079 19.9 0.3 0.012 16.0 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 GBG93402.1 - 0.00097 19.7 5.0 0.25 11.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 GBG93402.1 - 0.0032 17.0 0.0 0.0068 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Med4 PF10018.9 GBG93402.1 - 0.0035 17.0 2.5 0.01 15.5 2.5 1.8 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 G-alpha PF00503.20 GBG93402.1 - 0.0036 16.5 1.8 0.0088 15.2 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit T2SSE PF00437.20 GBG93402.1 - 0.0036 16.4 2.1 0.093 11.8 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein ABC_tran PF00005.27 GBG93402.1 - 0.011 16.3 0.2 0.062 13.8 0.0 2.4 2 0 0 2 2 1 0 ABC transporter GTP_EFTU PF00009.27 GBG93402.1 - 0.017 14.7 0.0 0.049 13.2 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain IIGP PF05049.13 GBG93402.1 - 0.022 13.8 0.0 0.08 12.0 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MCM PF00493.23 GBG93402.1 - 0.024 13.7 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_10 PF12846.7 GBG93402.1 - 0.049 12.6 0.4 2.1 7.2 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain Sigma54_activat PF00158.26 GBG93402.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain XhlA PF10779.9 GBG93402.1 - 0.058 13.6 4.3 0.16 12.2 4.3 1.7 1 0 0 1 1 1 0 Haemolysin XhlA TsaE PF02367.17 GBG93402.1 - 0.06 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 GBG93402.1 - 0.062 13.4 2.3 20 5.2 0.0 3.5 3 0 0 3 3 3 0 Dynamin family DUF815 PF05673.13 GBG93402.1 - 0.07 12.3 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 GBG93402.1 - 0.074 13.0 0.0 2.3 8.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 GBG93402.1 - 0.084 12.1 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain AAA_24 PF13479.6 GBG93402.1 - 0.091 12.5 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 GBG93402.1 - 0.11 12.8 0.2 1 9.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 GBG93402.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 GBG93402.1 - 0.19 11.5 0.6 5.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF4200 PF13863.6 GBG93402.1 - 0.2 12.0 8.5 0.017 15.5 2.8 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) DUF2385 PF09539.10 GBG93402.1 - 0.33 11.5 1.4 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) DUF16 PF01519.16 GBG93402.1 - 0.67 10.5 3.3 0.86 10.1 1.7 2.0 2 0 0 2 2 1 0 Protein of unknown function DUF16 BORCS7 PF16088.5 GBG93402.1 - 1.9 8.8 6.3 15 5.9 0.7 3.1 3 0 0 3 3 2 0 BLOC-1-related complex sub-unit 7 APG6_N PF17675.1 GBG93402.1 - 7.1 7.2 10.3 1.9 9.0 4.6 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4517 PF15006.6 GBG93402.1 - 7.3 6.7 7.0 0.27 11.3 0.3 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4517) gag-asp_proteas PF13975.6 GBG93404.1 - 0.0042 17.6 0.1 0.013 16.0 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93404.1 - 0.0065 17.1 0.1 0.019 15.6 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 GBG93404.1 - 0.031 14.4 1.9 0.048 13.7 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Topo_Zn_Ribbon PF08272.11 GBG93404.1 - 0.078 12.7 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Retrotrans_gag PF03732.17 GBG93405.1 - 0.02 15.2 0.1 0.14 12.5 0.0 2.5 1 1 1 2 2 2 0 Retrotransposon gag protein zf-CCHC_5 PF14787.6 GBG93405.1 - 0.039 13.7 3.6 0.081 12.6 3.6 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Pep_deformylase PF01327.21 GBG93405.1 - 0.11 12.1 2.3 0.24 11.0 2.3 1.5 1 0 0 1 1 1 0 Polypeptide deformylase Linker_histone PF00538.19 GBG93405.1 - 0.35 11.3 1.4 8.5 6.8 0.0 3.3 3 0 0 3 3 3 0 linker histone H1 and H5 family SDA1 PF05285.12 GBG93406.1 - 6.3 6.1 23.0 0.63 9.4 17.0 2.1 2 0 0 2 2 2 0 SDA1 SDA1 PF05285.12 GBG93407.1 - 0.00015 21.3 8.0 0.00015 21.3 8.0 1.0 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GBG93407.1 - 0.00017 20.1 6.2 0.00017 20.1 6.2 1.0 1 0 0 1 1 1 1 CDC45-like protein SpoIIP PF07454.11 GBG93407.1 - 0.0014 18.1 2.5 0.0014 18.1 2.5 1.0 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF4366 PF14283.6 GBG93407.1 - 0.0053 16.8 3.1 0.0068 16.4 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Eapp_C PF10238.9 GBG93407.1 - 0.015 15.3 2.8 0.016 15.3 2.8 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein U79_P34 PF03064.16 GBG93407.1 - 0.029 13.7 6.2 0.026 13.9 6.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDHD PF02862.17 GBG93407.1 - 0.073 13.2 0.5 0.065 13.4 0.5 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 GBG93407.1 - 0.087 12.0 2.4 0.082 12.1 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PTPRCAP PF15713.5 GBG93407.1 - 0.29 11.4 18.1 0.34 11.2 18.1 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 GBG93407.1 - 1.4 7.6 11.3 1.6 7.4 11.3 1.0 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 GBG93407.1 - 1.9 7.8 3.7 2 7.7 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EIIBC-GUT_N PF03612.14 GBG93407.1 - 1.9 8.2 6.1 3 7.5 6.1 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF5427 PF10310.9 GBG93407.1 - 2.1 7.2 11.5 2.3 7.1 11.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RNA_pol_Rpc4 PF05132.14 GBG93407.1 - 7.6 6.9 11.7 9.6 6.6 11.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 PIF1 PF05970.14 GBG93408.1 - 4.8e-51 174.0 0.0 6.4e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 GBG93408.1 - 6e-08 32.6 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GBG93408.1 - 0.0038 17.6 0.0 0.019 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GBG93408.1 - 0.06 13.6 0.1 0.27 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF4201 PF13870.6 GBG93409.1 - 8.1e-11 42.0 7.7 8.9e-09 35.3 2.6 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) MT PF12777.7 GBG93409.1 - 0.04 13.0 0.5 0.058 12.4 0.4 1.4 1 1 0 1 1 1 0 Microtubule-binding stalk of dynein motor ParB PF08775.10 GBG93409.1 - 0.057 13.9 3.1 0.086 13.3 2.3 1.7 1 1 1 2 2 2 0 ParB family SPATA24 PF15175.6 GBG93409.1 - 0.077 12.9 7.7 0.4 10.6 7.7 1.8 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF334 PF03904.13 GBG93409.1 - 0.094 12.2 2.9 0.099 12.2 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Sec34 PF04136.15 GBG93409.1 - 0.27 11.1 4.3 1.1 9.1 4.3 1.9 1 1 0 1 1 1 0 Sec34-like family KxDL PF10241.9 GBG93409.1 - 1.2 9.5 6.9 5 7.5 1.3 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein DUF1676 PF07898.13 GBG93410.1 - 0.00097 19.2 0.1 0.0013 18.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) ABC2_membrane_2 PF12679.7 GBG93410.1 - 0.0019 17.5 0.0 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3844 PF12955.7 GBG93410.1 - 0.0039 17.3 0.1 0.056 13.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) Glypican PF01153.19 GBG93410.1 - 0.081 11.7 2.8 0.096 11.5 2.8 1.1 1 0 0 1 1 1 0 Glypican DUF35_N PF12172.8 GBG93410.1 - 0.17 11.8 1.6 8.7 6.3 0.5 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Spt5_N PF11942.8 GBG93410.1 - 0.21 12.6 7.2 0.31 12.0 7.2 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Glyco_transf_5 PF08323.11 GBG93411.1 - 2.5e-16 60.1 0.0 3.6e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Presenilin PF01080.17 GBG93412.1 - 0.0025 16.6 0.6 0.0033 16.3 0.6 1.1 1 0 0 1 1 1 1 Presenilin DUF5427 PF10310.9 GBG93412.1 - 0.26 10.2 11.5 0.32 9.9 11.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Neur_chan_memb PF02932.16 GBG93412.1 - 0.72 9.9 7.0 0.92 9.5 7.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3987 PF13148.6 GBG93412.1 - 1.7 7.6 11.7 3.5 6.6 8.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Rtf2 PF04641.12 GBG93412.1 - 2 7.7 14.3 2.9 7.2 14.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger COX16 PF14138.6 GBG93412.1 - 9.6 6.8 9.7 11 6.6 8.6 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 PALP PF00291.25 GBG93413.1 - 0.2 11.0 0.0 0.25 10.7 0.0 1.4 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme GRP PF07172.11 GBG93414.1 - 0.029 15.0 13.5 0.029 15.0 13.5 3.4 2 1 1 3 3 3 0 Glycine rich protein family PdaC PF13739.6 GBG93414.1 - 0.052 14.5 1.4 0.077 14.0 1.4 1.1 1 0 0 1 1 1 0 Deacetylase PdaC Peptidase_S28 PF05577.12 GBG93417.1 - 1.6e-18 66.7 0.0 1.9e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 AP3D1 PF06375.11 GBG93417.1 - 0.042 14.1 2.7 0.65 10.2 0.4 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF2201_N PF13203.6 GBG93417.1 - 0.14 11.7 3.2 5.5 6.5 3.2 2.1 1 1 0 1 1 1 0 Putative metallopeptidase domain FAM176 PF14851.6 GBG93417.1 - 0.27 10.9 4.7 2.1 8.0 1.4 2.2 2 0 0 2 2 2 0 FAM176 family Ras PF00071.22 GBG93418.1 - 7.8e-47 158.9 0.4 1e-46 158.5 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GBG93418.1 - 3.8e-22 78.7 0.1 6.7e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GBG93418.1 - 1.1e-10 41.2 0.2 1.1e-10 41.2 0.2 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GBG93418.1 - 0.00016 21.3 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GBG93418.1 - 0.087 12.2 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GRP PF07172.11 GBG93418.1 - 6.3 7.6 29.3 9.4 7.0 3.9 2.4 2 0 0 2 2 2 0 Glycine rich protein family zf-CCHC PF00098.23 GBG93419.1 - 0.00014 21.7 1.8 0.0003 20.7 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle CDC27 PF09507.10 GBG93419.1 - 0.022 14.1 20.7 0.033 13.6 20.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Rgp1 PF08737.10 GBG93419.1 - 0.077 12.2 7.9 0.12 11.5 7.9 1.3 1 0 0 1 1 1 0 Rgp1 DUF572 PF04502.13 GBG93419.1 - 0.11 12.0 20.9 0.15 11.7 20.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CWC25 PF12542.8 GBG93420.1 - 0.26 12.2 2.1 0.38 11.7 0.1 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor TPPII_N PF12583.8 GBG93421.1 - 0.28 11.7 15.1 0.32 11.6 15.1 1.0 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal EVI2A PF05399.11 GBG93421.1 - 0.53 9.8 4.3 0.55 9.8 4.3 1.0 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF3583 PF12126.8 GBG93421.1 - 1.7 8.0 5.3 2.2 7.7 5.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3583) Glyco_transf_64 PF09258.10 GBG93423.1 - 2.4e-66 223.5 0.0 4.3e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 GBG93423.1 - 0.00051 19.7 7.1 0.85 9.1 7.1 3.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GBG93423.1 - 0.016 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.16 GBG93423.1 - 0.026 14.5 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF4604 PF15377.6 GBG93424.1 - 0.1 13.0 11.9 0.19 12.1 11.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Pkinase PF00069.25 GBG93426.1 - 5.7e-70 235.7 0.0 6.8e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG93426.1 - 6.6e-33 114.1 0.0 1.1e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GBG93426.1 - 0.0017 17.4 0.1 0.0024 16.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain GIY-YIG PF01541.24 GBG93429.1 - 3.1e-06 27.4 0.6 1.5e-05 25.1 0.1 2.5 2 0 0 2 2 2 1 GIY-YIG catalytic domain zf-CCHC PF00098.23 GBG93429.1 - 8e-05 22.5 2.9 0.00021 21.2 2.9 1.7 1 0 0 1 1 1 1 Zinc knuckle eIF-3c_N PF05470.12 GBG93429.1 - 0.082 11.2 10.2 0.49 8.7 10.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DDHD PF02862.17 GBG93429.1 - 0.094 12.9 4.1 0.21 11.7 4.1 1.6 1 0 0 1 1 1 0 DDHD domain zf-CCHC_4 PF14392.6 GBG93429.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle AP3D1 PF06375.11 GBG93429.1 - 0.65 10.2 21.9 2.2 8.5 1.8 2.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 LAP1C PF05609.12 GBG93429.1 - 0.67 9.0 12.0 1.1 8.3 12.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Borrelia_P83 PF05262.11 GBG93429.1 - 3.3 6.1 14.6 6.3 5.2 14.6 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Ank_2 PF12796.7 GBG93430.1 - 5.2e-12 46.2 0.0 1.6e-10 41.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GBG93430.1 - 8.7e-12 45.0 0.2 1.2e-06 28.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GBG93430.1 - 1.6e-10 41.0 0.0 1.7e-05 25.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GBG93430.1 - 2.7e-10 40.6 0.1 1.4e-05 25.6 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 GBG93430.1 - 1.4e-09 37.9 19.6 1.4e-09 37.9 19.6 2.5 2 0 0 2 2 2 1 MYND finger Ank_3 PF13606.6 GBG93430.1 - 2.9e-06 27.2 0.2 0.026 15.0 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat PolC_DP2 PF03833.13 GBG93430.1 - 0.00042 18.3 5.1 0.00065 17.7 5.1 1.2 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 DUF588 PF04535.12 GBG93433.1 - 3.9e-08 33.2 1.5 4.8e-08 32.9 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF588) Git3 PF11710.8 GBG93433.1 - 0.072 12.9 0.1 0.095 12.5 0.1 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 CarD_CdnL_TRCF PF02559.16 GBG93434.1 - 5.2e-11 43.1 1.5 1.7e-09 38.3 0.0 2.4 2 0 0 2 2 2 2 CarD-like/TRCF domain RT_RNaseH_2 PF17919.1 GBG93435.1 - 1.5e-32 111.6 0.1 3e-32 110.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93435.1 - 1.3e-28 99.4 0.1 2.8e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93435.1 - 2.3e-19 69.3 0.2 4.4e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG93435.1 - 5.8e-16 58.8 0.1 5.1e-15 55.7 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 GBG93435.1 - 0.048 13.9 1.6 0.058 13.6 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger rve_3 PF13683.6 GBG93435.1 - 0.093 12.5 0.1 0.38 10.6 0.1 2.2 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH_2 PF17919.1 GBG93436.1 - 5.4e-35 119.4 0.0 1.3e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93436.1 - 3.4e-30 104.4 0.0 7.6e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93436.1 - 2.9e-17 62.9 0.0 5.2e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG93436.1 - 1.6e-14 53.7 0.0 3.9e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC_3 PF13917.6 GBG93436.1 - 0.019 14.9 1.3 0.019 14.9 1.3 2.0 2 0 0 2 2 2 0 Zinc knuckle DUF5095 PF17016.5 GBG93436.1 - 0.074 12.7 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) IceA2 PF05862.11 GBG93436.1 - 0.2 11.6 0.1 0.42 10.6 0.1 1.5 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein zf-CCHC PF00098.23 GBG93436.1 - 1.5 9.0 3.2 3.6 7.8 3.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 GBG93437.1 - 0.084 11.6 1.9 0.1 11.3 1.9 1.1 1 0 0 1 1 1 0 Presenilin PTPRCAP PF15713.5 GBG93437.1 - 0.26 11.5 14.4 0.44 10.8 14.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC27 PF09507.10 GBG93437.1 - 0.34 10.2 14.5 0.44 9.9 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 GBG93437.1 - 0.59 8.4 11.5 0.76 8.0 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.13 GBG93437.1 - 1.9 6.8 3.0 2.4 6.4 3.0 1.0 1 0 0 1 1 1 0 Menin Sporozoite_P67 PF05642.11 GBG93437.1 - 1.9 6.5 8.5 2.5 6.1 8.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_C37 PF05416.12 GBG93437.1 - 2.4 6.6 5.0 3.2 6.1 5.0 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DNA_pol_phi PF04931.13 GBG93437.1 - 5 5.1 15.0 6.3 4.8 15.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 GBG93437.1 - 6.7 4.7 7.4 9.3 4.2 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HSP90 PF00183.18 GBG93437.1 - 6.8 5.5 13.0 8.7 5.1 13.0 1.1 1 0 0 1 1 1 0 Hsp90 protein RT_RNaseH_2 PF17919.1 GBG93438.1 - 2.2e-06 27.6 0.0 5.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93438.1 - 0.00048 20.4 0.0 0.0013 19.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HSCB_C PF07743.13 GBG93439.1 - 1.7e-16 60.5 5.9 3.6e-16 59.4 5.9 1.6 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 GBG93439.1 - 4.1e-06 26.8 0.4 7.6e-06 26.0 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain HscB_4_cys PF18256.1 GBG93439.1 - 0.0017 18.2 5.2 0.0059 16.4 5.2 2.0 1 0 0 1 1 1 1 Co-chaperone HscB tetracysteine metal binding motif DUF2353 PF09789.9 GBG93439.1 - 0.028 13.8 1.0 0.04 13.3 1.0 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) OrfB_Zn_ribbon PF07282.11 GBG93439.1 - 0.052 13.5 2.1 0.06 13.3 0.2 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Ank_2 PF12796.7 GBG93441.1 - 5.2e-12 46.2 0.0 1.6e-10 41.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GBG93441.1 - 8.7e-12 45.0 0.2 1.2e-06 28.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GBG93441.1 - 1.6e-10 41.0 0.0 1.7e-05 25.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GBG93441.1 - 2.7e-10 40.6 0.1 1.4e-05 25.6 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 GBG93441.1 - 1.4e-09 37.9 19.6 1.4e-09 37.9 19.6 2.5 2 0 0 2 2 2 1 MYND finger Ank_3 PF13606.6 GBG93441.1 - 2.9e-06 27.2 0.2 0.026 15.0 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat PolC_DP2 PF03833.13 GBG93441.1 - 0.00042 18.3 5.1 0.00065 17.7 5.1 1.2 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 YabA PF06156.13 GBG93442.1 - 0.04 14.5 3.9 0.04 14.5 3.9 3.3 2 1 0 2 2 2 0 Initiation control protein YabA Prominin PF05478.11 GBG93442.1 - 0.59 8.0 3.1 0.94 7.4 3.1 1.2 1 0 0 1 1 1 0 Prominin Integrase_H2C2 PF17921.1 GBG93445.1 - 6.7e-16 58.1 0.2 1.9e-15 56.7 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG93445.1 - 5.9e-14 52.3 0.0 2.9e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 GBG93445.1 - 9.3e-08 32.5 0.4 4.2e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 GBG93445.1 - 0.00011 22.0 0.5 0.00021 21.0 0.5 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 GBG93445.1 - 0.00022 21.8 0.7 0.0015 19.1 0.0 2.7 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GBG93445.1 - 0.0077 16.5 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GBG93445.1 - 0.017 15.3 0.0 0.045 14.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF659 PF04937.15 GBG93446.1 - 1.5e-31 109.3 0.0 2.6e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SDA1 PF05285.12 GBG93446.1 - 0.93 8.9 23.7 1.4 8.3 23.7 1.2 1 0 0 1 1 1 0 SDA1 DUF4820 PF16091.5 GBG93446.1 - 4.7 6.5 6.6 9.9 5.5 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RRN3 PF05327.11 GBG93446.1 - 4.8 5.6 7.4 7.9 4.9 7.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MPP6 PF10175.9 GBG93446.1 - 6.2 7.3 11.0 0.064 13.8 2.2 2.1 2 0 0 2 2 2 0 M-phase phosphoprotein 6 zf-CCHC PF00098.23 GBG93447.1 - 0.16 12.1 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle CAP_N PF01213.19 GBG93448.1 - 0.026 14.0 2.6 0.026 14.0 2.6 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF1180 PF06679.12 GBG93448.1 - 2.3 8.6 5.5 1.2 9.5 1.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) RVT_1 PF00078.27 GBG93449.1 - 9e-18 64.6 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG17 PF04108.12 GBG93449.1 - 0.086 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Cytochrom_C1 PF02167.15 GBG93451.1 - 1.3e-33 116.6 0.0 1.4e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C1 PF02167.15 GBG93452.1 - 2.4e-44 151.7 0.0 2.6e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 GBG93452.1 - 2.1e-05 24.7 0.1 3.1e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 GBG93452.1 - 0.00064 20.8 0.4 0.00095 20.3 0.4 1.5 1 1 0 1 1 1 1 Cytochrome c gag-asp_proteas PF13975.6 GBG93453.1 - 4.6e-07 30.3 0.0 1.2e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GBG93453.1 - 5.7e-07 29.3 2.4 1.4e-06 28.1 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 GBG93453.1 - 0.0001 22.8 0.0 0.00026 21.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GBG93453.1 - 0.00095 18.9 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GBG93453.1 - 0.0037 17.1 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Na_trans_assoc PF06512.13 GBG93453.1 - 0.04 14.2 12.2 0.98 9.7 9.8 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated zf-CCHC_2 PF13696.6 GBG93453.1 - 0.11 12.3 2.5 0.26 11.1 2.5 1.7 1 0 0 1 1 1 0 Zinc knuckle cNMP_binding PF00027.29 GBG93454.1 - 6.5e-09 35.7 0.0 8.3e-05 22.6 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PABP PF00658.18 GBG93455.1 - 9.6e-17 60.9 1.2 1.3e-16 60.5 1.2 1.2 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain CdiI_3 PF18616.1 GBG93455.1 - 0.043 13.7 0.0 0.045 13.6 0.0 1.0 1 0 0 1 1 1 0 CDI immunity proteins DUF659 PF04937.15 GBG93456.1 - 1.3e-26 93.3 0.0 2e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) XRCC4 PF06632.12 GBG93456.1 - 0.0011 17.9 7.6 0.0018 17.2 7.6 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PAP1 PF08601.10 GBG93456.1 - 5.1 6.7 13.2 7.6 6.2 13.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 APG17 PF04108.12 GBG93457.1 - 0.0094 15.1 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF2076 PF09849.9 GBG93457.1 - 0.27 11.2 6.8 0.38 10.8 6.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PEX11 PF05648.14 GBG93459.1 - 3.8e-08 33.1 0.0 5.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Asp_protease_2 PF13650.6 GBG93460.1 - 0.013 16.2 0.1 0.027 15.1 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 GBG93460.1 - 0.063 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 GBG93460.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4992 PF16383.5 GBG93460.1 - 0.19 11.3 0.1 0.49 9.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function Topo_Zn_Ribbon PF08272.11 GBG93460.1 - 0.2 11.3 3.8 0.091 12.4 0.3 2.3 3 0 0 3 3 3 0 Topoisomerase I zinc-ribbon-like zf-CCHC PF00098.23 GBG93460.1 - 0.65 10.2 2.0 1.4 9.2 2.0 1.6 1 0 0 1 1 1 0 Zinc knuckle LPMO_10 PF03067.15 GBG93461.1 - 0.00055 20.6 0.0 0.4 11.3 0.0 3.2 2 1 1 3 3 3 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DOMON PF03351.17 GBG93461.1 - 0.0077 16.4 0.0 0.023 14.9 0.0 1.8 2 0 0 2 2 2 1 DOMON domain CDC45 PF02724.14 GBG93463.1 - 0.018 13.3 10.4 0.025 12.9 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 GBG93463.1 - 0.092 11.8 12.0 0.13 11.3 12.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein LAP1C PF05609.12 GBG93463.1 - 0.37 9.8 7.0 0.51 9.4 7.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 GBG93463.1 - 0.43 8.7 15.1 0.55 8.4 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF167 PF02594.16 GBG93464.1 - 1e-14 54.4 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 zf-CCHC PF00098.23 GBG93465.1 - 0.14 12.3 3.9 0.075 13.1 1.9 1.6 2 0 0 2 2 2 0 Zinc knuckle ATE_N PF04376.13 GBG93465.1 - 0.94 9.9 4.5 1 9.8 0.0 2.8 3 0 0 3 3 3 0 Arginine-tRNA-protein transferase, N terminus Myb_DNA-bind_4 PF13837.6 GBG93466.1 - 1.6e-10 41.2 1.7 3.7e-10 40.0 0.6 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG93466.1 - 0.0069 16.7 1.6 0.012 15.9 0.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG93466.1 - 0.02 14.9 1.3 0.044 13.8 0.5 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF5427 PF10310.9 GBG93467.1 - 0.52 9.2 20.3 0.62 9.0 20.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Nop14 PF04147.12 GBG93467.1 - 0.57 8.3 47.7 0.71 8.0 47.7 1.1 1 0 0 1 1 1 0 Nop14-like family ORC6 PF05460.13 GBG93467.1 - 1.3 8.2 12.4 1.6 7.9 12.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RRN3 PF05327.11 GBG93467.1 - 2.6 6.5 20.4 2.9 6.3 20.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hid1 PF12722.7 GBG93467.1 - 2.7 6.0 14.4 2.7 6.0 14.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AF-4 PF05110.13 GBG93467.1 - 4.6 5.2 18.9 5.6 4.9 18.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SLC12 PF03522.15 GBG93467.1 - 6.3 5.7 11.9 7.2 5.5 11.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RT_RNaseH PF17917.1 GBG93469.1 - 2.9e-25 88.6 0.0 7.1e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93469.1 - 5.1e-24 84.2 0.0 1.7e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93469.1 - 5.8e-11 42.3 0.0 1.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GBG93469.1 - 0.032 14.5 0.9 0.16 12.3 0.1 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Complex1_LYR PF05347.15 GBG93469.1 - 0.093 12.8 0.8 22 5.2 0.0 2.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) SAP PF02037.27 GBG93472.1 - 3.6e-07 29.8 0.1 6.3e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 SAP domain Ish1 PF10281.9 GBG93472.1 - 0.038 14.3 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein RNA_pol_Rpc4 PF05132.14 GBG93472.1 - 0.46 10.9 8.2 0.26 11.7 0.6 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 rve PF00665.26 GBG93473.1 - 1.2e-14 54.5 0.0 2.5e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GBG93473.1 - 2.1e-14 53.4 0.1 4.5e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG93473.1 - 3.9e-06 27.3 0.0 7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93473.1 - 0.00036 21.1 0.0 0.00071 20.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GBG93473.1 - 0.012 15.9 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GBG93473.1 - 0.012 15.4 0.4 0.024 14.4 0.4 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 GBG93473.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG93474.1 - 0.00096 19.4 0.1 0.0046 17.2 0.1 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein NPV_P10 PF05531.12 GBG93474.1 - 0.22 12.0 0.6 3 8.4 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GBG93474.1 - 0.52 9.6 13.8 2 7.7 8.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Glyco_hydro_1 PF00232.18 GBG93475.1 - 2e-164 547.3 0.0 3.5e-164 546.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 GBG93475.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) RCDG1 PF15725.5 GBG93475.1 - 0.38 11.2 8.1 0.89 10.0 8.1 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein PRIMA1 PF16101.5 GBG93475.1 - 0.77 9.8 7.6 1.5 8.9 7.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GBG93475.1 - 0.84 9.1 5.2 1.3 8.4 5.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CobT PF06213.12 GBG93476.1 - 5.2 6.4 49.9 5.8 6.2 49.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT zf-CCHC PF00098.23 GBG93478.1 - 0.0034 17.4 1.5 0.0071 16.4 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Chromo PF00385.24 GBG93479.1 - 8.9e-05 22.3 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4187 PF13821.6 GBG93479.1 - 0.001 18.8 0.5 0.0024 17.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Retrotrans_gag PF03732.17 GBG93479.1 - 0.019 15.2 0.2 0.019 15.2 0.2 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC PF00098.23 GBG93480.1 - 9.6e-07 28.6 2.0 1.5e-06 28.0 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG93480.1 - 0.39 10.6 4.5 0.59 10.0 4.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GBG93481.1 - 1.1e-06 28.4 2.0 2e-06 27.6 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GBG93481.1 - 0.47 10.3 4.5 0.75 9.7 4.5 1.3 1 0 0 1 1 1 0 Zinc knuckle CDC37_N PF03234.14 GBG93481.1 - 8.8 7.3 20.6 3.5 8.5 13.8 2.8 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding Integrase_H2C2 PF17921.1 GBG93482.1 - 9.8e-20 70.4 0.2 1.8e-19 69.6 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GBG93482.1 - 2.8e-15 56.5 0.0 6.5e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG93482.1 - 0.00021 21.4 0.0 0.00057 20.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 GBG93482.1 - 0.012 15.9 0.0 0.043 14.1 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein Trypan_PARP PF05887.11 GBG93484.1 - 0.35 10.9 8.9 0.29 11.1 7.5 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Myb_DNA-bind_4 PF13837.6 GBG93485.1 - 3.6e-10 40.1 4.4 7.4e-09 35.9 0.3 3.2 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GBG93485.1 - 0.0034 17.7 0.2 0.013 15.8 0.2 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GBG93485.1 - 0.21 11.7 2.2 0.2 11.7 0.5 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain FTSW_RODA_SPOVE PF01098.19 GBG93486.1 - 0.034 13.1 2.3 0.036 13.1 2.3 1.0 1 0 0 1 1 1 0 Cell cycle protein LigD_N PF13298.6 GBG93486.1 - 0.043 14.1 0.0 0.054 13.8 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) DUF2244 PF10003.9 GBG93486.1 - 0.045 13.4 5.3 0.06 13.0 5.3 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Poxvirus_B22R_C PF13168.6 GBG93486.1 - 0.13 11.7 2.9 0.14 11.6 2.9 1.1 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal VirB3 PF05101.13 GBG93486.1 - 0.2 11.9 8.2 0.32 11.3 8.2 1.4 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein RRM_1 PF00076.22 GBG93487.1 - 5.6e-07 29.3 0.1 1.5e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) T3SSipB PF16535.5 GBG93487.1 - 0.11 13.0 10.1 0.061 13.8 7.4 1.8 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF4651 PF15513.6 GBG93487.1 - 0.16 11.8 0.0 0.49 10.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) LytR_C PF13399.6 GBG93487.1 - 0.54 11.3 3.6 1.4 10.0 2.1 2.4 1 1 1 2 2 2 0 LytR cell envelope-related transcriptional attenuator ApoC-I PF04691.12 GBG93487.1 - 5.5 7.0 7.1 2.6 8.1 3.3 2.4 2 1 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) eIF-3c_N PF05470.12 GBG93488.1 - 0.068 11.5 2.4 0.09 11.1 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.12 GBG93488.1 - 0.63 9.4 19.1 1.1 8.7 9.8 2.1 2 0 0 2 2 2 0 SDA1 DUF4637 PF15470.6 GBG93488.1 - 1.2 8.8 20.1 3.5 7.3 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) YL1 PF05764.13 GBG93488.1 - 3.1 7.9 21.3 2.6 8.1 11.4 2.1 2 0 0 2 2 2 0 YL1 nuclear protein PBP1_TM PF14812.6 GBG93488.1 - 4 7.9 13.9 17 5.9 9.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KIND PF16474.5 GBG93488.1 - 4.3 7.2 15.1 1.2 9.0 0.7 2.2 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain PI3K_1B_p101 PF10486.9 GBG93488.1 - 4.6 4.9 8.0 3.5 5.3 2.8 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Vfa1 PF08432.10 GBG93488.1 - 4.7 7.5 8.0 7.6 6.8 1.2 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GEN1_C PF18380.1 GBG93488.1 - 4.7 8.1 10.9 2.4 9.1 3.8 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain RPN2_C PF18004.1 GBG93488.1 - 7.6 6.4 14.3 4.5 7.2 5.6 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Myc_N PF01056.18 GBG93488.1 - 8.1 6.2 16.9 4.2 7.2 7.7 2.2 2 0 0 2 2 2 0 Myc amino-terminal region FAM176 PF14851.6 GBG93488.1 - 8.6 6.0 17.9 5.7 6.6 6.9 2.3 2 0 0 2 2 2 0 FAM176 family F-box-like PF12937.7 GBG93490.1 - 0.28 11.1 1.5 0.36 10.8 0.3 1.9 2 0 0 2 2 2 0 F-box-like Tim54 PF11711.8 GBG93493.1 - 0.23 10.2 9.2 0.013 14.3 2.6 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2151 PF10221.9 GBG93493.1 - 2.2 6.8 4.6 0.29 9.7 0.5 1.5 2 0 0 2 2 2 0 Cell cycle and development regulator NPR3 PF03666.13 GBG93493.1 - 2.3 6.9 8.2 5.7 5.6 8.2 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 WD40 PF00400.32 GBG93494.1 - 2.5e-10 40.7 0.0 6.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GBG93494.1 - 0.0033 17.7 0.0 0.02 15.2 0.0 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Cyanate_lyase PF02560.14 GBG93495.1 - 1.4e-30 104.9 0.2 1e-29 102.2 0.1 2.0 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HHH_9 PF17674.1 GBG93495.1 - 0.061 14.2 0.0 0.15 13.0 0.0 1.6 1 0 0 1 1 1 0 HHH domain ubiquitin PF00240.23 GBG93496.1 - 1.4e-13 50.4 0.0 1.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GBG93496.1 - 0.018 14.9 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 GBG93496.1 - 0.12 13.1 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD RT_RNaseH_2 PF17919.1 GBG93497.1 - 2.2e-22 79.0 0.0 3e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93497.1 - 1.4e-08 35.0 0.0 2.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4746 PF15928.5 GBG93501.1 - 5.4 6.3 17.2 8.1 5.8 17.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 GBG93501.1 - 9.6 5.5 28.2 12 5.2 28.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GBG93501.1 - 9.8 5.4 26.1 12 5.0 26.1 1.1 1 0 0 1 1 1 0 BUD22 Integrase_H2C2 PF17921.1 GBG93505.1 - 5.1e-15 55.3 0.1 1.1e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 GBG93505.1 - 0.00057 20.4 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93505.1 - 0.0006 20.4 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 GBG93505.1 - 0.0015 18.7 0.0 0.0056 16.9 0.0 2.0 2 0 0 2 2 2 1 H2C2 zinc finger PTPRCAP PF15713.5 GBG93505.1 - 0.012 15.9 1.9 0.012 15.9 1.9 3.1 3 1 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated Pkinase PF00069.25 GBG93506.1 - 2.1e-24 86.3 0.0 7.5e-24 84.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GBG93506.1 - 5.6e-20 71.7 0.0 1e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CCDC85 PF10226.9 GBG93506.1 - 0.0055 16.4 1.5 0.0094 15.6 1.5 1.4 1 0 0 1 1 1 1 CCDC85 family Focal_AT PF03623.13 GBG93506.1 - 0.023 14.7 3.5 0.044 13.8 3.5 1.4 1 0 0 1 1 1 0 Focal adhesion targeting region SHE3 PF17078.5 GBG93506.1 - 0.037 13.7 2.7 0.06 13.0 2.7 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CASP_C PF08172.12 GBG93506.1 - 0.046 13.0 2.7 0.073 12.4 2.7 1.2 1 0 0 1 1 1 0 CASP C terminal CENP-F_leu_zip PF10473.9 GBG93506.1 - 0.049 13.7 10.1 0.074 13.1 10.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 GBG93506.1 - 0.079 13.2 2.9 0.14 12.4 2.9 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 GBG93506.1 - 0.38 9.6 8.5 0.49 9.2 8.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MitMem_reg PF13012.6 GBG93506.1 - 0.67 10.4 2.8 1.6 9.2 2.6 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function UPF0242 PF06785.11 GBG93506.1 - 1.1 9.3 6.9 1.7 8.7 6.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 GBG93506.1 - 5.1 7.6 11.3 0.87 10.1 6.4 2.1 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_Maf PF03131.17 GBG93506.1 - 6 7.5 7.6 2.9 8.5 1.8 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor bZIP_1 PF00170.21 GBG93506.1 - 8.3 6.6 10.4 1.3 9.1 2.8 2.8 2 1 0 2 2 2 0 bZIP transcription factor ENTH PF01417.20 GBG93509.1 - 3.1e-40 137.1 0.0 4.4e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GBG93509.1 - 6.5e-05 22.1 0.0 9.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain RVT_1 PF00078.27 GBG93512.1 - 5.9e-30 104.4 0.2 8.9e-30 103.9 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GBG93512.1 - 3e-21 75.3 0.0 8.4e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93512.1 - 6.5e-09 36.0 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 GBG93512.1 - 3.6e-06 27.5 0.0 6.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GBG93512.1 - 0.0001 22.9 0.0 0.00023 21.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GBG93512.1 - 0.021 14.6 0.0 0.051 13.4 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 GBG93512.1 - 0.05 13.4 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Myb_DNA-bind_4 PF13837.6 GBG93513.1 - 2.7e-08 34.1 1.8 4.7e-08 33.3 1.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GBG93513.1 - 0.014 15.5 1.9 0.026 14.6 1.9 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Band_7 PF01145.25 GBG93514.1 - 0.00037 20.5 0.0 0.00041 20.4 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Chloroa_b-bind PF00504.21 GBG93515.1 - 3.6e-47 160.9 0.0 4.8e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2457 PF10446.9 GBG93516.1 - 0.0015 17.8 9.7 0.0016 17.7 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RXT2_N PF08595.11 GBG93516.1 - 0.043 13.8 1.9 0.059 13.4 1.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 GBG93516.1 - 0.12 12.1 1.2 0.16 11.7 1.2 1.2 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 GBG93516.1 - 0.13 11.6 14.2 0.16 11.2 14.2 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GBG93516.1 - 0.59 8.4 4.4 0.71 8.1 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GBG93516.1 - 1 7.4 12.6 1.2 7.1 12.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 GBG93516.1 - 2.3 8.7 17.6 3.7 8.0 17.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.13 GBG93516.1 - 2.3 8.0 5.0 3 7.7 5.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 GBG93516.1 - 2.4 6.6 5.7 3 6.3 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 GBG93516.1 - 2.7 8.5 22.4 6.5 7.2 22.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SGT1 PF07093.11 GBG93516.1 - 3.2 6.1 5.1 3.8 5.8 5.1 1.0 1 0 0 1 1 1 0 SGT1 protein Pericardin_rpt PF07054.11 GBG93516.1 - 4.6 7.5 5.4 26 5.0 0.6 3.4 2 1 1 3 3 3 0 Pericardin like repeat PPP4R2 PF09184.11 GBG93516.1 - 5.9 6.4 7.1 7.9 6.0 7.1 1.1 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 GBG93516.1 - 6.8 6.3 17.2 10 5.8 17.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GBG93516.1 - 6.9 4.8 8.0 8.3 4.5 8.0 1.0 1 0 0 1 1 1 0 Nop14-like family GCIP PF13324.6 GBG93516.1 - 7.6 6.1 7.9 10 5.6 7.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Astro_capsid_p PF12226.8 GBG93516.1 - 7.6 5.6 7.1 9.9 5.2 7.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RT_RNaseH_2 PF17919.1 GBG93517.1 - 3.2e-25 88.1 0.0 8.4e-25 86.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93517.1 - 2.3e-23 82.5 0.0 5.3e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GBG93517.1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG93517.1 - 3.9e-10 40.0 0.0 1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GBG93517.1 - 0.04 13.8 0.1 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Lipase_GDSL_2 PF13472.6 GBG93518.1 - 7.8e-21 75.3 0.1 1.9e-20 74.0 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GBG93518.1 - 2.1e-10 40.9 0.0 1.4e-09 38.3 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 GBG93518.1 - 1.2e-05 24.6 0.0 1.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 OSK domain MBOAT PF03062.19 GBG93519.1 - 1.6e-25 90.2 7.5 3.6e-25 89.1 7.1 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF459 PF04311.13 GBG93519.1 - 1.8e-11 43.7 0.0 2.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF459) Lipase_GDSL_2 PF13472.6 GBG93519.1 - 4.4e-07 30.5 0.0 1.2e-06 29.0 0.1 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family MBOAT_2 PF13813.6 GBG93519.1 - 6.2e-05 23.2 4.7 0.00021 21.5 4.7 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Lipase_GDSL PF00657.22 GBG93519.1 - 0.035 14.1 0.0 0.077 13.0 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Fzo_mitofusin PF04799.13 GBG93519.1 - 0.58 9.7 2.1 1.6 8.2 2.1 1.7 1 0 0 1 1 1 0 fzo-like conserved region RRM_1 PF00076.22 GBG93520.1 - 1.5e-19 69.5 0.0 1.7e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GBG93520.1 - 3.1e-05 23.7 0.0 4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 GBG93520.1 - 9.6e-05 22.4 0.0 0.00025 21.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 GBG93520.1 - 0.085 13.1 0.0 6.8 6.9 0.0 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 GBG93520.1 - 0.12 12.3 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif LNP1 PF15419.6 GBG93521.1 - 0.073 13.3 3.2 4.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 Cullin PF00888.22 GBG93522.1 - 1.4e-30 106.6 1.7 1.6e-30 106.3 1.7 1.0 1 0 0 1 1 1 1 Cullin family RVT_1 PF00078.27 GBG93523.1 - 2.8e-43 148.0 0.0 4.2e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SurA_N_2 PF13623.6 GBG93523.1 - 0.12 12.3 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 SurA N-terminal domain Beta_helix PF13229.6 GBG93524.1 - 2.4e-05 24.2 3.7 8.9e-05 22.4 3.7 1.9 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 GBG93524.1 - 0.3 11.7 14.5 69 4.2 0.1 6.8 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat EFF-AFF PF14884.6 GBG93526.1 - 0.04 12.1 0.0 0.057 11.5 0.0 1.1 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen RVT_1 PF00078.27 GBG93527.1 - 3.6e-09 36.5 0.0 1e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 GBG93529.1 - 5e-11 42.3 0.0 1.4e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.27 GBG93530.1 - 6.7e-29 101.0 0.0 1e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GBG93530.1 - 2.2e-19 69.3 0.4 4.6e-18 65.1 0.1 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GBG93530.1 - 1.3e-07 31.8 0.0 2.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GBG93530.1 - 0.0017 18.5 0.1 0.005 17.0 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 GBG93530.1 - 0.0045 16.7 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 GBG93530.1 - 0.0081 16.2 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 GBG93532.1 - 0.0018 18.2 2.0 0.0018 18.2 2.0 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 GBG93532.1 - 0.018 14.8 1.0 0.038 13.7 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2681 PF10883.8 GBG93532.1 - 7 7.1 13.3 3.9 7.9 3.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF3987 PF13148.6 GBG93532.1 - 9.4 5.1 14.8 0.24 10.3 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3987) RT_RNaseH_2 PF17919.1 GBG93533.1 - 8.4e-33 112.4 0.1 1.5e-32 111.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GBG93533.1 - 1.9e-21 76.3 0.4 5.3e-21 74.9 0.4 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GBG93533.1 - 1.7e-17 63.2 0.1 4.5e-17 61.9 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GBG93533.1 - 1e-10 41.5 0.1 1.8e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GBG93533.1 - 2.8e-09 37.2 0.0 7.9e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain EGF_MSP1_1 PF12946.7 GBG93534.1 - 0.14 12.2 0.4 0.14 12.2 0.4 1.8 2 0 0 2 2 2 0 MSP1 EGF domain 1 HEAT_2 PF13646.6 GBG93535.1 - 0.051 14.0 0.0 0.22 11.9 0.0 2.1 1 0 0 1 1 1 0 HEAT repeats RT_RNaseH PF17917.1 GBG93537.1 - 1.9e-22 79.5 0.0 3.8e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GBG93537.1 - 8.9e-20 70.6 0.0 2.1e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GBG93537.1 - 0.0098 16.1 0.1 0.047 14.0 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 GBG93538.1 - 2.6e-34 118.7 0.0 1.7e-33 116.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CLIP1_ZNF PF16641.5 GBG93538.1 - 0.0015 18.4 0.1 0.0025 17.6 0.1 1.4 1 0 0 1 1 1 1 CLIP1 zinc knuckle GHMP_kinases_C PF08544.13 GBG93539.1 - 0.029 14.7 0.2 4.2 7.8 0.1 2.9 2 2 0 2 2 2 0 GHMP kinases C terminal Casc1_N PF15927.5 GBG93539.1 - 0.1 12.3 15.3 0.21 11.2 15.3 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus LRR_8 PF13855.6 GBG93541.1 - 4.2e-12 45.6 16.8 1.6e-05 24.6 0.2 5.1 2 2 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 GBG93541.1 - 0.0015 18.9 14.4 1.2 9.6 0.1 5.4 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GBG93541.1 - 0.013 15.7 0.0 0.043 14.1 0.0 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Lectin_C PF00059.21 GBG93541.1 - 0.021 15.6 0.1 0.021 15.6 0.1 2.4 2 1 0 2 2 2 0 Lectin C-type domain LRR_9 PF14580.6 GBG93541.1 - 0.41 10.1 1.7 5.2 6.5 0.3 2.3 2 0 0 2 2 2 0 Leucine-rich repeat EGF_3 PF12947.7 GBG93541.1 - 0.71 10.1 16.1 1.7 8.9 6.5 3.3 2 0 0 2 2 2 0 EGF domain LRR_1 PF00560.33 GBG93541.1 - 4.6 8.2 12.9 1.3e+02 3.8 0.0 7.9 9 1 0 9 9 9 0 Leucine Rich Repeat # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Charophyta/Chara_braunii-Cbr_1.0/GCA_003427395.1_Cbr_1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Charophyta/Chara_braunii-Cbr_1.0/GCA_003427395.1_Cbr_1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Charophyta/Chara_braunii-Cbr_1.0/GCA_003427395.1_Cbr_1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Charophyta/Chara_braunii-Cbr_1.0/GCA_003427395.1_Cbr_1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 08:48:34 2019 # [ok]